TermID	Term	Enrichment	logP	Genes in Term	Target Genes in Term	Fraction of Targets in Term	Total Target Genes	Total Genes	Entrez Gene IDs	Gene Symbols
hsa04360	Axon guidance	4.88730394793709e-07	-14.5314548394054	127	85	0.0280343007915567	3032	6715	5365,2042,10154,29984,5362,6586,8482,5361,57556,5881,5364,56924,1020,1808,5998,54437,2051,2050,56920,4233,55558,10500,1072,7869,285220,4690,1630,4773,6405,9037,2534,1969,1945,3984,3688,2932,1946,5533,10512,6093,90249,8829,219699,10509,1948,10501,57689,84628,54910,6092,6091,80031,9723,2047,10298,1947,25,5880,4775,2048,10505,57522,22885,9423,2771,2046,2242,2049,5058,23380,1949,1944,23365,3845,5747,23654,64221,84448,9901,64218,10507,4776,1942,3265,3897	PLXNB3,EPHA3,PLXNC1,RHOD,PLXNA2,SLIT3,SEMA7A,PLXNA1,SEMA6A,RAC3,PLXNB1,PAK6,CDK5,DPYSL2,RGS3,SEMA5B,EPHB6,EPHB4,SEMA3G,MET,PLXNA3,SEMA6C,CFL1,SEMA3B,EPHA6,NCK1,DCC,NFATC2,SEMA3F,SEMA5A,FYN,EPHA2,EFNA4,LIMK1,ITGB1,GSK3B,EFNA5,PPP3CC,SEMA3C,ROCK1,UNC5A,NRP1,UNC5B,SEMA4B,EFNB2,SEMA6B,LRRC4C,NTNG2,SEMA4C,ROBO2,ROBO1,SEMA6D,SEMA3E,EPHB1,PAK4,EFNB1,ABL1,RAC2,NFATC3,EPHB2,SEMA4F,SRGAP1,ABLIM3,NTN1,GNAI2,EPHA8,FES,EPHB3,PAK1,SRGAP2,EFNB3,EFNA3,ARHGEF12,KRAS,PTK2,PLXNB2,ROBO3,ABLIM2,SRGAP3,SEMA4A,SEMA4D,NFATC4,EFNA1,HRAS,L1CAM
ko04360	Axon guidance	4.88730394793709e-07	-14.5314548394054	127	85	0.0280343007915567	3032	6715	5365,2042,10154,29984,5362,6586,8482,5361,57556,5881,5364,56924,1020,1808,5998,54437,2051,2050,56920,4233,55558,10500,1072,7869,285220,4690,1630,4773,6405,9037,2534,1969,1945,3984,3688,2932,1946,5533,10512,6093,90249,8829,219699,10509,1948,10501,57689,84628,54910,6092,6091,80031,9723,2047,10298,1947,25,5880,4775,2048,10505,57522,22885,9423,2771,2046,2242,2049,5058,23380,1949,1944,23365,3845,5747,23654,64221,84448,9901,64218,10507,4776,1942,3265,3897	PLXNB3,EPHA3,PLXNC1,RHOD,PLXNA2,SLIT3,SEMA7A,PLXNA1,SEMA6A,RAC3,PLXNB1,PAK6,CDK5,DPYSL2,RGS3,SEMA5B,EPHB6,EPHB4,SEMA3G,MET,PLXNA3,SEMA6C,CFL1,SEMA3B,EPHA6,NCK1,DCC,NFATC2,SEMA3F,SEMA5A,FYN,EPHA2,EFNA4,LIMK1,ITGB1,GSK3B,EFNA5,PPP3CC,SEMA3C,ROCK1,UNC5A,NRP1,UNC5B,SEMA4B,EFNB2,SEMA6B,LRRC4C,NTNG2,SEMA4C,ROBO2,ROBO1,SEMA6D,SEMA3E,EPHB1,PAK4,EFNB1,ABL1,RAC2,NFATC3,EPHB2,SEMA4F,SRGAP1,ABLIM3,NTN1,GNAI2,EPHA8,FES,EPHB3,PAK1,SRGAP2,EFNB3,EFNA3,ARHGEF12,KRAS,PTK2,PLXNB2,ROBO3,ABLIM2,SRGAP3,SEMA4A,SEMA4D,NFATC4,EFNA1,HRAS,L1CAM
ko04144	Endocytosis	5.20932334139567e-06	-12.1650605875252	203	123	0.0405672823218997	3032	6715	7189,26052,10015,84552,9230,3949,5979,2870,28964,89853,80230,3303,8411,84612,30011,9727,161,23527,8853,10193,5867,1785,5662,1212,4233,3815,3306,84249,116988,131890,7879,4914,3312,868,9525,5868,857,867,51028,5869,2348,3310,6455,4088,22905,51160,29082,4087,64145,2321,56904,80223,5590,7251,128866,27183,6011,56288,60682,64411,23550,2869,440073,6457,11311,4092,29924,7046,5338,859,7042,7048,8766,6714,7037,84364,3105,23396,26056,2261,1601,50807,30846,116983,9922,11059,3107,2065,4091,2264,116984,390243,79643,55616,154,3560,51652,55048,8394,116987,1956,3304,55040,55738,155382,9146,10254,160,11031,116985,408,26286,1211,5337,30844,23096,91782,3265,5878,9135,1234,1436,10938	TRAF6,DNM3,PDCD6IP,PARD6G,RAB11B,LDLR,RET,GRK6,GIT1,MVB12B,RUFY1,HSPA1A,EEA1,PARD6B,SH3KBP1,RAB11FIP3,AP2A2,ACAP2,ASAP2,RNF41,RAB4A,DNM2,PSD,CLTB,MET,KIT,HSPA2,PSD2,AGAP3,GRK7,RAB7A,NTRK1,HSPA8,CBLB,VPS4B,RAB5A,CAV1,CBL,VPS36,RAB5B,FOLR1,HSPA6,SH3GL1,SMAD3,EPN2,VPS28,CHMP4A,SMAD2,ZFYVE20,FLT1,SH3GLB2,RAB11FIP1,PRKCZ,TSG101,CHMP4B,VPS4A,GRK1,PARD3,SMAP1,ARAP3,PSD4,GRK5,IQSEC3,SH3GL3,VPS45,SMAD7,EPN1,TGFBR1,PLD2,CAV3,TGFB2,TGFBR2,RAB11A,SRC,TFRC,ARFGAP2,HLA-A,PIP5K1C,RAB11FIP5,FGFR3,DAB2,ASAP1,EHD2,ACAP3,IQSEC1,WWP1,HLA-C,ERBB3,SMAD6,FGFR4,ARAP2,FOLR4,CHMP6,ASAP3,ADRB2,IL2RB,CHMP3,VPS37C,PIP5K1A,AGAP1,EGFR,HSPA1B,EPN3,ARFGAP1,VPS37D,HGS,STAM2,AP2A1,RAB31,ARAP1,ARRB1,ARFGAP3,CLTA,PLD1,EHD4,IQSEC2,CHMP7,HRAS,RAB5C,RABEP1,CCR5,CSF1R,EHD1
hsa04144	Endocytosis	5.20932334139567e-06	-12.1650605875252	203	123	0.0405672823218997	3032	6715	7189,26052,10015,84552,9230,3949,5979,2870,28964,89853,80230,3303,8411,84612,30011,9727,161,23527,8853,10193,5867,1785,5662,1212,4233,3815,3306,84249,116988,131890,7879,4914,3312,868,9525,5868,857,867,51028,5869,2348,3310,6455,4088,22905,51160,29082,4087,64145,2321,56904,80223,5590,7251,128866,27183,6011,56288,60682,64411,23550,2869,440073,6457,11311,4092,29924,7046,5338,859,7042,7048,8766,6714,7037,84364,3105,23396,26056,2261,1601,50807,30846,116983,9922,11059,3107,2065,4091,2264,116984,390243,79643,55616,154,3560,51652,55048,8394,116987,1956,3304,55040,55738,155382,9146,10254,160,11031,116985,408,26286,1211,5337,30844,23096,91782,3265,5878,9135,1234,1436,10938	TRAF6,DNM3,PDCD6IP,PARD6G,RAB11B,LDLR,RET,GRK6,GIT1,MVB12B,RUFY1,HSPA1A,EEA1,PARD6B,SH3KBP1,RAB11FIP3,AP2A2,ACAP2,ASAP2,RNF41,RAB4A,DNM2,PSD,CLTB,MET,KIT,HSPA2,PSD2,AGAP3,GRK7,RAB7A,NTRK1,HSPA8,CBLB,VPS4B,RAB5A,CAV1,CBL,VPS36,RAB5B,FOLR1,HSPA6,SH3GL1,SMAD3,EPN2,VPS28,CHMP4A,SMAD2,ZFYVE20,FLT1,SH3GLB2,RAB11FIP1,PRKCZ,TSG101,CHMP4B,VPS4A,GRK1,PARD3,SMAP1,ARAP3,PSD4,GRK5,IQSEC3,SH3GL3,VPS45,SMAD7,EPN1,TGFBR1,PLD2,CAV3,TGFB2,TGFBR2,RAB11A,SRC,TFRC,ARFGAP2,HLA-A,PIP5K1C,RAB11FIP5,FGFR3,DAB2,ASAP1,EHD2,ACAP3,IQSEC1,WWP1,HLA-C,ERBB3,SMAD6,FGFR4,ARAP2,FOLR4,CHMP6,ASAP3,ADRB2,IL2RB,CHMP3,VPS37C,PIP5K1A,AGAP1,EGFR,HSPA1B,EPN3,ARFGAP1,VPS37D,HGS,STAM2,AP2A1,RAB31,ARAP1,ARRB1,ARFGAP3,CLTA,PLD1,EHD4,IQSEC2,CHMP7,HRAS,RAB5C,RABEP1,CCR5,CSF1R,EHD1
ko04666	Fc gamma R-mediated phagocytosis	1.87066127866358e-05	-10.8866334716605	91	61	0.0201187335092348	3032	6715	10163,5321,10810,81873,3636,3635,5894,7410,8877,5338,5578,4067,1794,100137049,23396,7409,1399,8611,5880,8853,2209,50807,23533,10092,5580,5336,653361,5296,5290,1785,8503,4082,6850,8398,1072,6199,123745,5058,27040,10451,2213,207,5295,55616,8612,65108,8394,10552,2214,5788,283748,2934,5335,7454,255189,10000,3984,2212,6198,5337,56848	WASF2,PLA2G4A,WASF3,ARPC5L,INPPL1,INPP5D,RAF1,VAV2,SPHK1,PLD2,PRKCA,LYN,DOCK2,PLA2G4B,PIP5K1C,VAV1,CRKL,PPAP2A,RAC2,ASAP2,FCGR1A,ASAP1,PIK3R5,ARPC5,PRKCD,PLCG2,NCF1,PIK3R2,PIK3CA,DNM2,PIK3R3,MARCKS,SYK,PLA2G6,CFL1,RPS6KB2,PLA2G4E,PAK1,LAT,VAV3,FCGR2B,AKT1,PIK3R1,ASAP3,PPAP2C,MARCKSL1,PIP5K1A,ARPC1A,FCGR3A,PTPRC,PLA2G4D,GSN,PLCG1,WAS,PLA2G4F,AKT3,LIMK1,FCGR2A,RPS6KB1,PLD1,SPHK2
hsa04666	Fc gamma R-mediated phagocytosis	1.87066127866358e-05	-10.8866334716605	91	61	0.0201187335092348	3032	6715	10163,5321,10810,81873,3636,3635,5894,7410,8877,5338,5578,4067,1794,100137049,23396,7409,1399,8611,5880,8853,2209,50807,23533,10092,5580,5336,653361,5296,5290,1785,8503,4082,6850,8398,1072,6199,123745,5058,27040,10451,2213,207,5295,55616,8612,65108,8394,10552,2214,5788,283748,2934,5335,7454,255189,10000,3984,2212,6198,5337,56848	WASF2,PLA2G4A,WASF3,ARPC5L,INPPL1,INPP5D,RAF1,VAV2,SPHK1,PLD2,PRKCA,LYN,DOCK2,PLA2G4B,PIP5K1C,VAV1,CRKL,PPAP2A,RAC2,ASAP2,FCGR1A,ASAP1,PIK3R5,ARPC5,PRKCD,PLCG2,NCF1,PIK3R2,PIK3CA,DNM2,PIK3R3,MARCKS,SYK,PLA2G6,CFL1,RPS6KB2,PLA2G4E,PAK1,LAT,VAV3,FCGR2B,AKT1,PIK3R1,ASAP3,PPAP2C,MARCKSL1,PIP5K1A,ARPC1A,FCGR3A,PTPRC,PLA2G4D,GSN,PLCG1,WAS,PLA2G4F,AKT3,LIMK1,FCGR2A,RPS6KB1,PLD1,SPHK2
hsa04010	MAPK signaling pathway	5.21265636136856e-05	-9.86183588091037	259	148	0.0488126649076517	3032	6715	4149,1850,8912,9254,51701,5578,1432,5881,5606,6196,4790,5971,11221,779,994,5159,5567,1849,2318,468,4914,4909,3312,8550,5613,2316,4772,93589,23542,3310,8605,7132,5778,5533,3315,4208,84867,5922,23162,7048,1847,100137049,2122,3725,5880,4775,6788,4609,5601,2872,8911,123745,2264,5058,5871,6237,7867,27006,51295,100506012,1852,3845,5605,1956,2248,355,9261,3554,255189,4217,4915,5321,2005,7189,5607,6195,5894,22808,5566,5495,3925,56940,3303,2317,1399,5154,786,3551,8986,4791,1386,3306,10369,4215,27092,207,2249,2257,929,1846,9064,2260,2246,8517,23118,1616,80824,4616,6722,784,5536,774,6300,1844,9344,7186,1326,7046,7042,9252,2261,5600,6885,9020,22800,1843,51347,2254,5923,5609,3164,9693,777,773,2353,9479,3304,283748,2768,1647,10000,8817,26281,356,408,3265,51776,1649	MAX,DUSP8,CACNA1H,CACNA2D2,NLK,PRKCA,MAPK14,RAC3,MAP2K3,RPS6KA2,NFKB1,RELB,DUSP10,CACNA1S,CDC25B,PDGFRB,PRKACB,DUSP7,FLNC,ATF4,NTRK1,NTF4,HSPA8,MAPKAPK5,PRKX,FLNA,NFATC1,CACNA2D4,MAPK8IP2,HSPA6,PLA2G4C,TNFRSF1A,PTPN7,PPP3CC,HSPB1,MEF2C,PTPN5,RASA2,MAPK8IP3,TGFBR2,DUSP5,PLA2G4B,MECOM,JUN,RAC2,NFATC3,STK3,MYC,MAPK9,MKNK2,CACNA1I,PLA2G4E,FGFR4,PAK1,MAP4K2,RRAS,MAPKAPK3,FGF22,ECSIT,PPP5D1,DUSP9,KRAS,MAP2K2,EGFR,FGF3,FAS,MAPKAPK2,IL1R1,PLA2G4F,MAP3K5,NTRK2,PLA2G4A,ELK4,TRAF6,MAP2K5,RPS6KA1,RAF1,MRAS,PRKACA,PPM1B,STMN1,DUSP22,HSPA1A,FLNB,CRKL,PDGFA,CACNG1,IKBKB,RPS6KA4,NFKB2,ATF2,HSPA2,CACNG2,MAP3K3,CACNG4,AKT1,FGF4,FGF12,CD14,DUSP4,MAP3K6,FGFR1,FGF1,IKBKG,TAB2,DAXX,DUSP16,GADD45B,SRF,CACNB3,PPP5C,CACNA1B,MAPK12,DUSP2,TAOK2,TRAF2,MAP3K8,TGFBR1,TGFB2,RPS6KA5,FGFR3,MAPK11,MAP3K7,MAP3K14,RRAS2,DUSP1,TAOK3,FGF9,RASGRF1,MAP2K7,NR4A1,RAPGEF2,CACNA1E,CACNA1A,FOS,MAPK8IP1,HSPA1B,PLA2G4D,GNA12,GADD45A,AKT3,FGF18,FGF20,FASLG,ARRB1,HRAS,ZAK,DDIT3
ko04010	MAPK signaling pathway	5.21265636136856e-05	-9.86183588091037	259	148	0.0488126649076517	3032	6715	4149,1850,8912,9254,51701,5578,1432,5881,5606,6196,4790,11221,5971,779,994,5567,5159,1849,2318,468,4914,4909,3312,8550,5613,2316,4772,93589,23542,3310,8605,7132,5778,5533,3315,4208,84867,5922,23162,7048,1847,100137049,2122,3725,5880,4775,6788,4609,5601,2872,8911,123745,5058,2264,5871,6237,7867,27006,51295,100506012,1852,3845,5605,1956,2248,355,9261,3554,255189,4217,4915,5321,2005,7189,5607,6195,5894,22808,5566,5495,3925,56940,3303,2317,1399,5154,786,3551,8986,4791,1386,3306,10369,4215,27092,207,2249,2257,929,1846,9064,2260,2246,8517,1616,23118,80824,4616,6722,784,5536,774,6300,1844,9344,7186,1326,7046,7042,9252,2261,5600,6885,9020,22800,1843,51347,2254,5923,5609,3164,9693,777,773,2353,9479,3304,283748,2768,1647,10000,26281,8817,408,356,51776,3265,1649	MAX,DUSP8,CACNA1H,CACNA2D2,NLK,PRKCA,MAPK14,RAC3,MAP2K3,RPS6KA2,NFKB1,DUSP10,RELB,CACNA1S,CDC25B,PRKACB,PDGFRB,DUSP7,FLNC,ATF4,NTRK1,NTF4,HSPA8,MAPKAPK5,PRKX,FLNA,NFATC1,CACNA2D4,MAPK8IP2,HSPA6,PLA2G4C,TNFRSF1A,PTPN7,PPP3CC,HSPB1,MEF2C,PTPN5,RASA2,MAPK8IP3,TGFBR2,DUSP5,PLA2G4B,MECOM,JUN,RAC2,NFATC3,STK3,MYC,MAPK9,MKNK2,CACNA1I,PLA2G4E,PAK1,FGFR4,MAP4K2,RRAS,MAPKAPK3,FGF22,ECSIT,PPP5D1,DUSP9,KRAS,MAP2K2,EGFR,FGF3,FAS,MAPKAPK2,IL1R1,PLA2G4F,MAP3K5,NTRK2,PLA2G4A,ELK4,TRAF6,MAP2K5,RPS6KA1,RAF1,MRAS,PRKACA,PPM1B,STMN1,DUSP22,HSPA1A,FLNB,CRKL,PDGFA,CACNG1,IKBKB,RPS6KA4,NFKB2,ATF2,HSPA2,CACNG2,MAP3K3,CACNG4,AKT1,FGF4,FGF12,CD14,DUSP4,MAP3K6,FGFR1,FGF1,IKBKG,DAXX,TAB2,DUSP16,GADD45B,SRF,CACNB3,PPP5C,CACNA1B,MAPK12,DUSP2,TAOK2,TRAF2,MAP3K8,TGFBR1,TGFB2,RPS6KA5,FGFR3,MAPK11,MAP3K7,MAP3K14,RRAS2,DUSP1,TAOK3,FGF9,RASGRF1,MAP2K7,NR4A1,RAPGEF2,CACNA1E,CACNA1A,FOS,MAPK8IP1,HSPA1B,PLA2G4D,GNA12,GADD45A,AKT3,FGF20,FGF18,ARRB1,FASLG,ZAK,HRAS,DDIT3
hsa05200	Pathways in cancer	6.00149687477503e-05	-9.72091654772774	327	182	0.0600263852242744	3032	6715	2736,4149,2034,6256,5979,1488,1026,5578,329,5881,898,23604,3909,1499,4286,4790,5296,5290,9915,10342,5159,7704,9978,1630,1019,7039,4914,7476,868,2271,83593,7422,7478,5898,5228,83439,5335,4087,8312,3576,3688,4254,2932,1855,861,9618,7188,1870,3918,3066,2335,3728,1495,3655,5900,54205,7048,2122,650,3725,5880,3675,23533,80326,4609,5601,4313,3913,89780,613,7483,3915,27006,3845,6921,6932,7477,5605,1613,1956,6934,2248,355,54361,3091,4792,5337,1487,4843,54583,9134,7189,1284,2475,10928,5894,6513,11211,2064,324,637,1441,5154,1399,595,999,5899,3551,5336,8503,4233,4791,6688,3815,1856,1164,8321,5914,207,330,6923,7170,2249,3326,2257,1871,5727,7481,867,2260,2246,4088,5743,8517,7185,7475,112398,3082,7187,4089,3911,405,4318,8325,7186,7472,11186,7046,7042,284217,2950,2113,8323,3914,25,2261,1163,3320,6774,7484,6258,2254,5295,5747,2323,2353,8772,7175,7849,8030,81029,10000,8453,8817,26281,6469,356,6776,3685,7855,3265,1436	GLI2,MAX,EPAS1,RXRA,RET,CTBP2,CDKN1A,PRKCA,BIRC2,RAC3,CCNE1,DAPK2,LAMA3,CTNNB1,MITF,NFKB1,PIK3R2,PIK3CA,ARNT2,TFG,PDGFRB,ZBTB16,RBX1,DCC,CDK4,TGFA,NTRK1,WNT7A,CBLB,FH,RASSF5,VEGFA,WNT8A,RALA,PGF,TCF7L1,PLCG1,SMAD2,AXIN1,IL8,ITGB1,KITLG,GSK3B,DVL1,RUNX1,TRAF4,TRAF5,E2F2,LAMC2,HDAC2,FN1,JUP,CTNNA1,ITGA6,RALGDS,CYCS,TGFBR2,MECOM,BMP2,JUN,RAC2,ITGA3,PIK3R5,WNT10A,MYC,MAPK9,MMP2,LAMB2,WNT3A,BCR,WNT9A,LAMC1,FGF22,KRAS,TCEB1,TCF7,WNT7B,MAP2K2,DAPK3,EGFR,TCF7L2,FGF3,FAS,WNT4,HIF1A,NFKBIA,PLD1,CTBP1,NOS2,EGLN1,CCNE2,TRAF6,COL4A2,MTOR,RALBP1,RAF1,SLC2A1,FZD10,ERBB2,APC,BID,CSF3R,PDGFA,CRKL,CCND1,CDH1,RALB,IKBKB,PLCG2,PIK3R3,MET,NFKB2,SPI1,KIT,DVL2,CKS2,FZD1,RARA,AKT1,BIRC3,TCEB2,TPM3,FGF4,HSP90AB1,FGF12,E2F3,PTCH1,WNT11,CBL,FGFR1,FGF1,SMAD3,PTGS2,IKBKG,TRAF1,WNT6,EGLN2,HGF,TRAF3,SMAD4,LAMA5,ARNT,MMP9,FZD8,TRAF2,WNT2,RASSF1,TGFBR1,TGFB2,LAMA1,GSTP1,ETS1,FZD6,LAMB3,ABL1,FGFR3,CKS1B,HSP90AA1,STAT3,WNT9B,RXRG,FGF9,PIK3R1,PTK2,FLT3LG,FOS,FADD,TPR,PAX8,CCDC6,WNT5B,AKT3,CUL2,FGF18,FGF20,SHH,FASLG,STAT5A,ITGAV,FZD5,HRAS,CSF1R
hsa04390	Hippo signaling pathway	0.000165133612642937	-8.70875563815988	154	92	0.0303430079155673	3032	6715	23291,3397,2736,84552,4771,71,11211,64398,324,7531,329,84612,595,7161,1499,999,5518,1739,7004,7159,5499,5521,1856,6591,8321,23418,1454,7476,10971,7481,60485,79981,7478,2246,4088,3689,5515,83439,353500,4087,7475,374,8312,85407,5590,2932,27113,60,5054,1855,657,126374,5522,4089,55844,56288,1453,8994,122786,8325,1495,7472,4092,11186,3398,7046,7042,7048,8323,650,6788,3993,80326,4609,3996,896,268,89780,7484,7483,286204,23286,6932,7477,23513,6934,54361,81029,1740,7534,7855,8945	FBXW11,ID1,GLI2,PARD6G,NF2,ACTG1,FZD10,MPP5,APC,YWHAE,BIRC2,PARD6B,CCND1,TP73,CTNNB1,CDH1,PPP2R1A,DLG1,TEAD4,TP53BP2,PPP1CA,PPP2R2B,DVL2,SNAI2,FZD1,CRB1,CSNK1E,WNT7A,YWHAQ,WNT11,SAV1,FRMD1,WNT8A,FGF1,SMAD3,ITGB2,PPP2CA,TCF7L1,BMP8A,SMAD2,WNT6,AREG,AXIN1,NKD1,PRKCZ,GSK3B,BBC3,ACTB,SERPINE1,DVL1,BMPR1A,WTIP,PPP2R2C,SMAD4,PPP2R2D,PARD3,CSNK1D,LIMD1,FRMD6,FZD8,CTNNA1,WNT2,SMAD7,RASSF1,ID2,TGFBR1,TGFB2,TGFBR2,FZD6,BMP2,STK3,LLGL2,WNT10A,MYC,LLGL1,CCND3,AMH,WNT3A,WNT9B,WNT9A,CRB2,WWC1,TCF7,WNT7B,SCRIB,TCF7L2,WNT4,WNT5B,DLG2,YWHAZ,FZD5,BTRC
ko04390	Hippo signaling pathway	0.000165133612642937	-8.70875563815988	154	92	0.0303430079155673	3032	6715	23291,3397,2736,84552,4771,71,11211,64398,324,7531,329,84612,595,7161,1499,999,5518,1739,7004,7159,5499,5521,1856,6591,8321,23418,1454,7476,10971,7481,60485,79981,7478,2246,4088,3689,5515,83439,353500,4087,7475,374,8312,85407,5590,2932,27113,60,5054,1855,657,126374,5522,4089,55844,56288,1453,8994,122786,8325,1495,7472,4092,11186,3398,7046,7042,7048,8323,650,6788,3993,80326,4609,3996,896,268,89780,7484,7483,286204,23286,6932,7477,23513,6934,54361,81029,1740,7534,7855,8945	FBXW11,ID1,GLI2,PARD6G,NF2,ACTG1,FZD10,MPP5,APC,YWHAE,BIRC2,PARD6B,CCND1,TP73,CTNNB1,CDH1,PPP2R1A,DLG1,TEAD4,TP53BP2,PPP1CA,PPP2R2B,DVL2,SNAI2,FZD1,CRB1,CSNK1E,WNT7A,YWHAQ,WNT11,SAV1,FRMD1,WNT8A,FGF1,SMAD3,ITGB2,PPP2CA,TCF7L1,BMP8A,SMAD2,WNT6,AREG,AXIN1,NKD1,PRKCZ,GSK3B,BBC3,ACTB,SERPINE1,DVL1,BMPR1A,WTIP,PPP2R2C,SMAD4,PPP2R2D,PARD3,CSNK1D,LIMD1,FRMD6,FZD8,CTNNA1,WNT2,SMAD7,RASSF1,ID2,TGFBR1,TGFB2,TGFBR2,FZD6,BMP2,STK3,LLGL2,WNT10A,MYC,LLGL1,CCND3,AMH,WNT3A,WNT9B,WNT9A,CRB2,WWC1,TCF7,WNT7B,SCRIB,TCF7L2,WNT4,WNT5B,DLG2,YWHAZ,FZD5,BTRC
hsa04911	Insulin secretion	0.000219576646622371	-8.42380919905511	87	56	0.0184696569920844	3032	6715	64764,3779,1388,6513,9586,5578,5566,5331,6833,3651,3781,3783,5864,112,109,779,1385,5330,1386,477,818,815,5567,1131,9699,113,148327,468,2740,157855,11069,480,3778,107,90993,5613,6262,481,3710,2767,3630,817,476,2645,486,6804,111,8773,114,816,3782,5332,3780,3767,117,478	CREB3L2,KCNMB1,ATF6B,SLC2A1,CREB5,PRKCA,PRKACA,PLCB3,ABCC8,PDX1,KCNN2,KCNN4,RAB3A,ADCY6,ADCY3,CACNA1S,CREB1,PLCB2,ATF2,ATP1A2,CAMK2G,CAMK2A,PRKACB,CHRM3,RIMS2,ADCY7,CREB3L4,ATF4,GLP1R,KCNU1,RAPGEF4,ATP1A4,KCNMA1,ADCY1,CREB3L1,PRKX,RYR2,ATP1B1,ITPR3,GNA11,INS,CAMK2D,ATP1A1,GCK,FXYD2,STX1A,ADCY5,SNAP23,ADCY8,CAMK2B,KCNN3,PLCB4,KCNN1,KCNJ11,ADCYAP1R1,ATP1A3
ko04915	Estrogen signaling pathway	0.000225324524847561	-8.39796886226668	100	63	0.020778364116095	3032	6715	4318,64764,1839,399694,1388,5894,3763,9586,5566,6714,3303,25759,5331,3725,51806,6464,53358,23533,5580,5296,4313,5290,8503,112,109,3320,1385,5330,1386,2771,3306,5567,6667,113,148327,468,207,3326,9568,3312,5295,107,90993,5613,3845,3710,2353,5605,1956,3304,3310,3762,3765,111,10000,114,3708,163688,5332,2289,2852,3265,810	MMP9,CREB3L2,HBEGF,SHC4,ATF6B,RAF1,KCNJ6,CREB5,PRKACA,SRC,HSPA1A,SHC2,PLCB3,JUN,CALML5,SHC1,SHC3,PIK3R5,PRKCD,PIK3R2,MMP2,PIK3CA,PIK3R3,ADCY6,ADCY3,HSP90AA1,CREB1,PLCB2,ATF2,GNAI2,HSPA2,PRKACB,SP1,ADCY7,CREB3L4,ATF4,AKT1,HSP90AB1,GABBR2,HSPA8,PIK3R1,ADCY1,CREB3L1,PRKX,KRAS,ITPR3,FOS,MAP2K2,EGFR,HSPA1B,HSPA6,KCNJ5,KCNJ9,ADCY5,AKT3,ADCY8,ITPR1,CALML6,PLCB4,FKBP5,GPER1,HRAS,CALML3
hsa04915	Estrogen signaling pathway	0.000225324524847561	-8.39796886226668	100	63	0.020778364116095	3032	6715	4318,64764,1839,399694,1388,5894,3763,9586,5566,6714,3303,25759,5331,3725,51806,6464,53358,23533,5580,5296,4313,5290,8503,112,109,3320,1385,5330,1386,2771,3306,5567,6667,113,148327,468,207,3326,9568,3312,5295,107,90993,5613,3845,3710,2353,5605,1956,3304,3310,3762,3765,111,10000,114,3708,163688,5332,2289,2852,3265,810	MMP9,CREB3L2,HBEGF,SHC4,ATF6B,RAF1,KCNJ6,CREB5,PRKACA,SRC,HSPA1A,SHC2,PLCB3,JUN,CALML5,SHC1,SHC3,PIK3R5,PRKCD,PIK3R2,MMP2,PIK3CA,PIK3R3,ADCY6,ADCY3,HSP90AA1,CREB1,PLCB2,ATF2,GNAI2,HSPA2,PRKACB,SP1,ADCY7,CREB3L4,ATF4,AKT1,HSP90AB1,GABBR2,HSPA8,PIK3R1,ADCY1,CREB3L1,PRKX,KRAS,ITPR3,FOS,MAP2K2,EGFR,HSPA1B,HSPA6,KCNJ5,KCNJ9,ADCY5,AKT3,ADCY8,ITPR1,CALML6,PLCB4,FKBP5,GPER1,HRAS,CALML3
hsa05166	HTLV-I infection	0.000234336238433227	-8.35875355760172	263	147	0.0484828496042216	3032	6715	3601,1026,3113,64682,5111,1499,4790,5296,1739,10393,5290,109,5971,4603,5159,5567,468,1019,7476,5613,4772,1959,7478,3689,4087,291,114,7132,2932,5533,1855,8829,8061,1870,23373,51433,8850,1958,7094,1111,7048,4055,811,3725,4775,23533,80326,4609,5902,706,112,545,3107,89780,57804,7483,6237,9184,4605,3845,7477,55697,3554,54361,996,2114,2224,4792,387332,5425,2005,3600,11211,6513,324,22808,821,8498,5566,5424,595,5154,3551,7419,8503,51434,4791,6688,1386,1856,8321,113,4215,207,115650,991,1871,107,4773,7481,701,467,7416,8697,4088,8517,4488,8881,7514,7475,6722,4089,6908,8325,6929,7472,7046,7042,2113,8323,3105,3383,3123,896,1385,9020,22800,7484,4487,2648,5295,1437,3560,2353,200186,5426,7015,2874,111,81029,10000,472,6776,4776,7855,3265,29945	IL15RA,CDKN1A,HLA-DPA1,ANAPC1,PCNA,CTNNB1,NFKB1,PIK3R2,DLG1,ANAPC10,PIK3CA,ADCY3,RELB,MYBL1,PDGFRB,PRKACB,ATF4,CDK4,WNT7A,PRKX,NFATC1,EGR2,WNT8A,ITGB2,SMAD2,SLC25A4,ADCY8,TNFRSF1A,GSK3B,PPP3CC,DVL1,NRP1,FOSL1,E2F2,CRTC1,ANAPC5,KAT2B,EGR1,TLN1,CHEK1,TGFBR2,LTBR,CALR,JUN,NFATC3,PIK3R5,WNT10A,MYC,RANBP1,TSPO,ADCY6,ATR,HLA-C,WNT3A,POLD4,WNT9A,RRAS,BUB3,MYBL2,KRAS,WNT7B,VAC14,IL1R1,WNT4,CDC27,ETS2,FDPS,NFKBIA,TBPL2,POLD2,ELK4,IL15,FZD10,SLC2A1,APC,MRAS,CANX,RANBP3,PRKACA,POLD1,CCND1,PDGFA,IKBKB,VDAC3,PIK3R3,ANAPC7,NFKB2,SPI1,ATF2,DVL2,FZD1,ADCY7,MAP3K3,AKT1,TNFRSF13C,CDC20,E2F3,ADCY1,NFATC2,WNT11,BUB1B,ATF3,VDAC1,CDC23,SMAD3,IKBKG,MSX2,CDC16,XPO1,WNT6,SRF,SMAD4,TBP,FZD8,TCF3,WNT2,TGFBR1,TGFB2,ETS1,FZD6,HLA-A,ICAM1,HLA-DRB1,CCND3,CREB1,MAP3K14,RRAS2,WNT9B,MSX1,KAT2A,PIK3R1,CSF2,IL2RB,FOS,CRTC2,POLE,TERT,GPS2,ADCY5,WNT5B,AKT3,ATM,STAT5A,NFATC4,FZD5,HRAS,ANAPC4
ko05166	HTLV-I infection	0.000234336238433227	-8.35875355760172	263	147	0.0484828496042216	3032	6715	3601,1026,3113,64682,5111,1499,4790,5296,1739,10393,5290,109,5971,4603,5159,5567,468,1019,7476,5613,4772,1959,7478,3689,4087,291,114,7132,2932,5533,1855,8829,8061,1870,23373,51433,8850,1958,7094,1111,7048,4055,811,3725,4775,23533,80326,4609,5902,706,112,545,3107,89780,57804,7483,6237,9184,4605,3845,7477,55697,3554,54361,996,2114,2224,4792,387332,5425,2005,3600,11211,6513,324,22808,821,8498,5566,5424,595,5154,3551,7419,8503,51434,4791,6688,1386,1856,8321,113,4215,207,115650,991,1871,107,4773,7481,701,467,7416,8697,4088,8517,4488,8881,7514,7475,6722,4089,6908,8325,6929,7472,7046,7042,2113,8323,3105,3383,3123,896,1385,9020,22800,7484,4487,2648,5295,1437,3560,2353,200186,5426,7015,2874,111,81029,10000,472,6776,4776,7855,3265,29945	IL15RA,CDKN1A,HLA-DPA1,ANAPC1,PCNA,CTNNB1,NFKB1,PIK3R2,DLG1,ANAPC10,PIK3CA,ADCY3,RELB,MYBL1,PDGFRB,PRKACB,ATF4,CDK4,WNT7A,PRKX,NFATC1,EGR2,WNT8A,ITGB2,SMAD2,SLC25A4,ADCY8,TNFRSF1A,GSK3B,PPP3CC,DVL1,NRP1,FOSL1,E2F2,CRTC1,ANAPC5,KAT2B,EGR1,TLN1,CHEK1,TGFBR2,LTBR,CALR,JUN,NFATC3,PIK3R5,WNT10A,MYC,RANBP1,TSPO,ADCY6,ATR,HLA-C,WNT3A,POLD4,WNT9A,RRAS,BUB3,MYBL2,KRAS,WNT7B,VAC14,IL1R1,WNT4,CDC27,ETS2,FDPS,NFKBIA,TBPL2,POLD2,ELK4,IL15,FZD10,SLC2A1,APC,MRAS,CANX,RANBP3,PRKACA,POLD1,CCND1,PDGFA,IKBKB,VDAC3,PIK3R3,ANAPC7,NFKB2,SPI1,ATF2,DVL2,FZD1,ADCY7,MAP3K3,AKT1,TNFRSF13C,CDC20,E2F3,ADCY1,NFATC2,WNT11,BUB1B,ATF3,VDAC1,CDC23,SMAD3,IKBKG,MSX2,CDC16,XPO1,WNT6,SRF,SMAD4,TBP,FZD8,TCF3,WNT2,TGFBR1,TGFB2,ETS1,FZD6,HLA-A,ICAM1,HLA-DRB1,CCND3,CREB1,MAP3K14,RRAS2,WNT9B,MSX1,KAT2A,PIK3R1,CSF2,IL2RB,FOS,CRTC2,POLE,TERT,GPS2,ADCY5,WNT5B,AKT3,ATM,STAT5A,NFATC4,FZD5,HRAS,ANAPC4
hsa05205	Proteoglycans in cancer	0.000356233715226597	-7.93992353907086	225	127	0.0418865435356201	3032	6715	1839,71,3339,2475,5894,11211,288,2064,22808,1026,5578,1432,6382,5566,2317,595,1499,7448,5336,5296,54776,5290,8503,2017,5499,4233,7074,2817,815,5567,8321,2318,207,84309,2249,5777,7476,2257,868,406991,5727,5613,7481,857,2316,7422,867,3710,2260,117581,7478,2246,817,5335,4087,7475,10855,3688,3082,60,6198,6093,27250,6300,4318,2335,4659,8325,7410,7472,6385,859,7042,6714,8323,7023,286,23533,4609,80326,4313,9138,5781,6548,5962,5600,2065,960,89780,6774,22800,818,7484,6199,5058,5170,2254,7483,5829,6237,1975,5329,27006,5295,23365,3845,7477,5747,5605,1956,2248,355,54361,3091,81029,10000,816,8817,26281,3708,356,4660,1655,3685,7855,4478,3265	HBEGF,ACTG1,HSPG2,MTOR,RAF1,FZD10,ANK3,ERBB2,MRAS,CDKN1A,PRKCA,MAPK14,SDC1,PRKACA,FLNB,CCND1,CTNNB1,VTN,PLCG2,PIK3R2,PPP1R12C,PIK3CA,PIK3R3,CTTN,PPP1CA,MET,TIAM1,GPC1,CAMK2A,PRKACB,FZD1,FLNC,AKT1,NUDT16L1,FGF4,PTPN6,WNT7A,FGF12,CBLB,MIR21,PTCH1,PRKX,WNT11,CAV1,FLNA,VEGFA,CBL,ITPR3,FGFR1,TWIST2,WNT8A,FGF1,CAMK2D,PLCG1,SMAD2,WNT6,HPSE,ITGB1,HGF,ACTB,RPS6KB1,ROCK1,PDCD4,MAPK12,MMP9,FN1,PPP1R12A,FZD8,VAV2,WNT2,SDC4,CAV3,TGFB2,SRC,FZD6,TFAP4,ANK1,PIK3R5,MYC,WNT10A,MMP2,ARHGEF1,PTPN11,SLC9A1,RDX,MAPK11,ERBB3,CD44,WNT3A,STAT3,RRAS2,CAMK2G,WNT9B,RPS6KB2,PAK1,PDPK1,FGF9,WNT9A,PXN,RRAS,EIF4B,PLAUR,FGF22,PIK3R1,ARHGEF12,KRAS,WNT7B,PTK2,MAP2K2,EGFR,FGF3,FAS,WNT4,HIF1A,WNT5B,AKT3,CAMK2B,FGF18,FGF20,ITPR1,FASLG,PPP1R12B,DDX5,ITGAV,FZD5,MSN,HRAS
ko05205	Proteoglycans in cancer	0.000356233715226597	-7.93992353907086	225	127	0.0418865435356201	3032	6715	1839,71,3339,2475,5894,11211,288,2064,22808,1026,5578,1432,6382,5566,2317,595,1499,7448,5336,5296,54776,5290,8503,2017,5499,4233,7074,2817,815,5567,8321,2318,207,84309,2249,5777,7476,2257,868,406991,5727,5613,7481,857,2316,7422,867,3710,2260,117581,7478,2246,817,5335,4087,7475,10855,3688,3082,60,6198,6093,27250,6300,4318,2335,4659,8325,7410,7472,6385,859,7042,6714,8323,7023,286,23533,4609,80326,4313,9138,5781,6548,5962,5600,2065,960,89780,6774,22800,818,7484,6199,5058,5170,2254,7483,5829,6237,1975,5329,27006,5295,23365,3845,7477,5747,5605,1956,2248,355,54361,3091,81029,10000,816,8817,26281,3708,356,4660,1655,3685,7855,4478,3265	HBEGF,ACTG1,HSPG2,MTOR,RAF1,FZD10,ANK3,ERBB2,MRAS,CDKN1A,PRKCA,MAPK14,SDC1,PRKACA,FLNB,CCND1,CTNNB1,VTN,PLCG2,PIK3R2,PPP1R12C,PIK3CA,PIK3R3,CTTN,PPP1CA,MET,TIAM1,GPC1,CAMK2A,PRKACB,FZD1,FLNC,AKT1,NUDT16L1,FGF4,PTPN6,WNT7A,FGF12,CBLB,MIR21,PTCH1,PRKX,WNT11,CAV1,FLNA,VEGFA,CBL,ITPR3,FGFR1,TWIST2,WNT8A,FGF1,CAMK2D,PLCG1,SMAD2,WNT6,HPSE,ITGB1,HGF,ACTB,RPS6KB1,ROCK1,PDCD4,MAPK12,MMP9,FN1,PPP1R12A,FZD8,VAV2,WNT2,SDC4,CAV3,TGFB2,SRC,FZD6,TFAP4,ANK1,PIK3R5,MYC,WNT10A,MMP2,ARHGEF1,PTPN11,SLC9A1,RDX,MAPK11,ERBB3,CD44,WNT3A,STAT3,RRAS2,CAMK2G,WNT9B,RPS6KB2,PAK1,PDPK1,FGF9,WNT9A,PXN,RRAS,EIF4B,PLAUR,FGF22,PIK3R1,ARHGEF12,KRAS,WNT7B,PTK2,MAP2K2,EGFR,FGF3,FAS,WNT4,HIF1A,WNT5B,AKT3,CAMK2B,FGF18,FGF20,ITPR1,FASLG,PPP1R12B,DDX5,ITGAV,FZD5,MSN,HRAS
hsa04664	Fc epsilon RI signaling pathway	0.000396021384307916	-7.83404234739022	70	46	0.0151715039577836	3032	6715	5321,2207,3635,5894,7410,3596,3565,3937,5578,4067,1432,5881,100137049,5606,7409,5880,23533,5580,5336,5296,5601,5290,8503,5600,2205,6850,123745,5170,3562,27040,10451,207,5609,5295,3845,1437,5605,283748,5335,8605,2534,255189,10000,3265,3567,6300	PLA2G4A,FCER1G,INPP5D,RAF1,VAV2,IL13,IL4,LCP2,PRKCA,LYN,MAPK14,RAC3,PLA2G4B,MAP2K3,VAV1,RAC2,PIK3R5,PRKCD,PLCG2,PIK3R2,MAPK9,PIK3CA,PIK3R3,MAPK11,FCER1A,SYK,PLA2G4E,PDPK1,IL3,LAT,VAV3,AKT1,MAP2K7,PIK3R1,KRAS,CSF2,MAP2K2,PLA2G4D,PLCG1,PLA2G4C,FYN,PLA2G4F,AKT3,HRAS,IL5,MAPK12
ko04664	Fc epsilon RI signaling pathway	0.000396021384307916	-7.83404234739022	70	46	0.0151715039577836	3032	6715	5321,2207,3635,5894,7410,3596,3565,3937,5578,4067,1432,5881,100137049,5606,7409,5880,23533,5580,5336,5296,5601,5290,8503,5600,2205,6850,123745,5170,3562,27040,10451,207,5609,5295,3845,1437,5605,283748,5335,8605,2534,255189,10000,3265,3567,6300	PLA2G4A,FCER1G,INPP5D,RAF1,VAV2,IL13,IL4,LCP2,PRKCA,LYN,MAPK14,RAC3,PLA2G4B,MAP2K3,VAV1,RAC2,PIK3R5,PRKCD,PLCG2,PIK3R2,MAPK9,PIK3CA,PIK3R3,MAPK11,FCER1A,SYK,PLA2G4E,PDPK1,IL3,LAT,VAV3,AKT1,MAP2K7,PIK3R1,KRAS,CSF2,MAP2K2,PLA2G4D,PLCG1,PLA2G4C,FYN,PLA2G4F,AKT3,HRAS,IL5,MAPK12
hsa04710	Circadian rhythm	0.000438324238857102	-7.73255165009028	30	23	0.00758575197889182	3032	6715	5563,6097,5564,23291,9978,1454,5565,5562,8553,6095,8864,53632,51422,5187,79365,406,6500,1408,8863,1385,9572,1453,8945	PRKAA2,RORC,PRKAB1,FBXW11,RBX1,CSNK1E,PRKAB2,PRKAA1,BHLHE40,RORA,PER2,PRKAG3,PRKAG2,PER1,BHLHE41,ARNTL,SKP1,CRY2,PER3,CREB1,NR1D1,CSNK1D,BTRC
ko04710	Circadian rhythm	0.000438324238857102	-7.73255165009028	30	23	0.00758575197889182	3032	6715	5563,6097,5564,23291,9978,1454,5565,5562,8553,6095,8864,53632,51422,5187,79365,406,6500,1408,8863,1385,9572,1453,8945	PRKAA2,RORC,PRKAB1,FBXW11,RBX1,CSNK1E,PRKAB2,PRKAA1,BHLHE40,RORA,PER2,PRKAG3,PRKAG2,PER1,BHLHE41,ARNTL,SKP1,CRY2,PER3,CREB1,NR1D1,CSNK1D,BTRC
hsa04066	HIF-1 signaling pathway	0.000542113547603258	-7.52003508104316	106	65	0.0214379947229551	3032	6715	2475,6513,2064,1026,5578,3162,5336,4790,5296,5290,8503,1977,2023,815,5160,2597,207,6923,9978,5208,5209,80201,7422,3630,817,5335,112398,1978,2321,226,5054,6198,284,405,253314,7037,4055,23533,5211,2872,6774,3101,818,6199,5210,3460,5295,1906,3939,5161,6921,3570,5605,1956,3643,5230,3091,816,10000,8453,3099,51378,3098,4843,54583	MTOR,SLC2A1,ERBB2,CDKN1A,PRKCA,HMOX1,PLCG2,NFKB1,PIK3R2,PIK3CA,PIK3R3,EIF4E,ENO1,CAMK2A,PDHA1,GAPDH,AKT1,TCEB2,RBX1,PFKFB2,PFKFB3,HKDC1,VEGFA,INS,CAMK2D,PLCG1,EGLN2,EIF4EBP1,FLT1,ALDOA,SERPINE1,RPS6KB1,ANGPT1,ARNT,EIF4E1B,TFRC,LTBR,PIK3R5,PFKL,MKNK2,STAT3,HK3,CAMK2G,RPS6KB2,PFKFB4,IFNGR2,PIK3R1,EDN1,LDHA,PDHA2,TCEB1,IL6R,MAP2K2,EGFR,INSR,PGK1,HIF1A,CAMK2B,AKT3,CUL2,HK2,ANGPT4,HK1,NOS2,EGLN1
ko04520	Adherens junction	0.000686532493879738	-7.28385700120381	73	47	0.0155013192612137	3032	6715	4008,10163,10810,10580,71,1495,2064,51701,7046,7082,88,7048,6714,5881,5880,5770,1499,999,5818,4233,6885,7414,6591,9855,81607,2241,5777,5797,87,6932,2260,10458,6934,1956,4088,5792,83439,5795,2534,4087,7454,3643,52,81,60,4089,56288	LMO7,WASF2,WASF3,SORBS1,ACTG1,CTNNA1,ERBB2,NLK,TGFBR1,TJP1,ACTN2,TGFBR2,SRC,RAC3,RAC2,PTPN1,CTNNB1,CDH1,PVRL1,MET,MAP3K7,VCL,SNAI2,FARP2,PVRL4,FER,PTPN6,PTPRM,ACTN1,TCF7,FGFR1,BAIAP2,TCF7L2,EGFR,SMAD3,PTPRF,TCF7L1,PTPRJ,FYN,SMAD2,WAS,INSR,ACP1,ACTN4,ACTB,SMAD4,PARD3
hsa04520	Adherens junction	0.000686532493879738	-7.28385700120381	73	47	0.0155013192612137	3032	6715	4008,10163,10810,10580,71,1495,2064,51701,7046,7082,88,7048,6714,5881,5880,5770,1499,999,5818,4233,6885,7414,6591,9855,81607,2241,5777,5797,87,6932,2260,10458,6934,1956,4088,5792,83439,5795,2534,4087,7454,3643,52,81,60,4089,56288	LMO7,WASF2,WASF3,SORBS1,ACTG1,CTNNA1,ERBB2,NLK,TGFBR1,TJP1,ACTN2,TGFBR2,SRC,RAC3,RAC2,PTPN1,CTNNB1,CDH1,PVRL1,MET,MAP3K7,VCL,SNAI2,FARP2,PVRL4,FER,PTPN6,PTPRM,ACTN1,TCF7,FGFR1,BAIAP2,TCF7L2,EGFR,SMAD3,PTPRF,TCF7L1,PTPRJ,FYN,SMAD2,WAS,INSR,ACP1,ACTN4,ACTB,SMAD4,PARD3
hsa04115	p53 signaling pathway	0.000864262495699448	-7.05363402083553	68	44	0.0145118733509235	3032	6715	9134,63970,7249,3732,8493,4194,1111,54205,575,1026,891,637,898,7161,595,143686,6477,5366,896,51512,55240,545,64065,3486,901,1643,83667,1019,6241,51246,900,27244,9540,983,355,64326,1647,50484,4616,27113,472,5054,317,2810	CCNE2,TP53AIP1,TSC2,CD82,PPM1D,MDM4,CHEK1,CYCS,BAI1,CDKN1A,CCNB1,BID,CCNE1,TP73,CCND1,SESN3,SIAH1,PMAIP1,CCND3,GTSE1,STEAP3,ATR,PERP,IGFBP3,CCNG2,DDB2,SESN2,CDK4,RRM2,SHISA5,CCNG1,SESN1,TP53I3,CDK1,FAS,RFWD2,GADD45A,RRM2B,GADD45B,BBC3,ATM,SERPINE1,APAF1,SFN
ko04115	p53 signaling pathway	0.000864262495699448	-7.05363402083553	68	44	0.0145118733509235	3032	6715	9134,63970,7249,3732,8493,4194,1111,54205,575,1026,891,637,898,7161,595,143686,6477,5366,896,51512,55240,545,64065,3486,901,1643,83667,1019,6241,51246,900,27244,9540,983,355,64326,1647,50484,4616,27113,472,5054,317,2810	CCNE2,TP53AIP1,TSC2,CD82,PPM1D,MDM4,CHEK1,CYCS,BAI1,CDKN1A,CCNB1,BID,CCNE1,TP73,CCND1,SESN3,SIAH1,PMAIP1,CCND3,GTSE1,STEAP3,ATR,PERP,IGFBP3,CCNG2,DDB2,SESN2,CDK4,RRM2,SHISA5,CCNG1,SESN1,TP53I3,CDK1,FAS,RFWD2,GADD45A,RRM2B,GADD45B,BBC3,ATM,SERPINE1,APAF1,SFN
hsa04070	Phosphatidylinositol signaling system	0.000889341702567787	-7.02502902895773	81	51	0.016820580474934	3032	6715	3707,4534,8760,3636,8525,89869,3635,1609,1606,8527,113026,10423,5578,8867,5305,23396,1040,5331,56623,51763,64768,51806,3631,5298,23533,3632,54928,5336,5296,5290,8503,8871,5330,3613,3612,5333,5295,79837,8394,3710,5286,55361,55300,5335,9162,3708,163688,8821,5332,5287,810	ITPKB,MTM1,CDS2,INPPL1,DGKZ,PLCZ1,INPP5D,DGKQ,DGKA,DGKD,PLCD3,CDIPT,PRKCA,SYNJ1,PIP4K2A,PIP5K1C,CDS1,PLCB3,INPP5E,INPP5K,IPPK,CALML5,INPP4A,PI4KB,PIK3R5,INPP5A,IMPAD1,PLCG2,PIK3R2,PIK3CA,PIK3R3,SYNJ2,PLCB2,IMPA2,IMPA1,PLCD1,PIK3R1,PIP4K2C,PIP5K1A,ITPR3,PIK3C2A,PI4K2A,PI4K2B,PLCG1,DGKI,ITPR1,CALML6,INPP4B,PLCB4,PIK3C2B,CALML3
ko04070	Phosphatidylinositol signaling system	0.000889341702567787	-7.02502902895773	81	51	0.016820580474934	3032	6715	3707,4534,8760,3636,8525,89869,3635,1609,1606,8527,113026,10423,5578,8867,5305,23396,1040,5331,56623,51763,64768,51806,3631,5298,23533,3632,54928,5336,5296,5290,8503,8871,5330,3613,3612,5333,5295,79837,8394,3710,5286,55361,55300,5335,9162,3708,163688,8821,5332,5287,810	ITPKB,MTM1,CDS2,INPPL1,DGKZ,PLCZ1,INPP5D,DGKQ,DGKA,DGKD,PLCD3,CDIPT,PRKCA,SYNJ1,PIP4K2A,PIP5K1C,CDS1,PLCB3,INPP5E,INPP5K,IPPK,CALML5,INPP4A,PI4KB,PIK3R5,INPP5A,IMPAD1,PLCG2,PIK3R2,PIK3CA,PIK3R3,SYNJ2,PLCB2,IMPA2,IMPA1,PLCD1,PIK3R1,PIP4K2C,PIP5K1A,ITPR3,PIK3C2A,PI4K2A,PI4K2B,PLCG1,DGKI,ITPR1,CALML6,INPP4B,PLCB4,PIK3C2B,CALML3
ko04810	Regulation of actin cytoskeleton	0.000920561637155448	-6.99052659901639	215	120	0.0395778364116095	3032	6715	10163,71,54434,1793,5894,4627,22808,324,55740,28964,81624,4628,5881,5154,7409,1399,56924,55845,5216,5296,89846,54776,5290,8503,22801,5499,3687,8515,3694,7414,7074,4636,5159,1072,345456,2147,54961,91807,2249,2257,93408,1132,87,929,10627,2260,3630,2246,3689,2934,7454,3984,3645,4638,3681,3688,81,60,6093,103910,2245,81873,2335,4659,8874,3655,7410,1128,88,5305,10298,6714,10788,23396,2261,5880,3675,3696,23533,10092,9138,6548,5962,128239,3672,623,22800,1131,2264,5058,23191,56034,10451,2254,5829,6237,27006,5295,79837,23365,3845,5747,8394,26999,9564,10552,1729,5605,1956,10458,2248,2768,8817,26281,4660,3685,3691,4478,3265,50649	WASF2,ACTG1,SSH1,DOCK1,RAF1,MYH9,MRAS,APC,ENAH,GIT1,DIAPH3,MYH10,RAC3,PDGFA,VAV1,CRKL,PAK6,BRK1,PFN1,PIK3R2,FGD3,PPP1R12C,PIK3CA,PIK3R3,ITGA11,PPP1CA,ITGAX,ITGA10,ITGB6,VCL,TIAM1,MYL5,PDGFRB,CFL1,PFN3,F2,SSH3,MYLK3,FGF4,FGF12,MYL10,CHRM4,ACTN1,CD14,MYL12A,FGFR1,INS,FGF1,ITGB2,GSN,WAS,LIMK1,INSRR,MYLK,ITGAD,ITGB1,ACTN4,ACTB,ROCK1,MYL12B,FGD1,ARPC5L,FN1,PPP1R12A,ARHGEF7,ITGA6,VAV2,CHRM1,ACTN2,PIP4K2A,PAK4,SRC,IQGAP2,PIP5K1C,FGFR3,RAC2,ITGA3,ITGB8,PIK3R5,ARPC5,ARHGEF1,SLC9A1,RDX,IQGAP3,ITGA1,BDKRB1,RRAS2,CHRM3,FGFR4,PAK1,CYFIP1,PDGFC,VAV3,FGF9,PXN,RRAS,FGF22,PIK3R1,PIP4K2C,ARHGEF12,KRAS,PTK2,PIP5K1A,CYFIP2,BCAR1,ARPC1A,DIAPH1,MAP2K2,EGFR,BAIAP2,FGF3,GNA12,FGF18,FGF20,PPP1R12B,ITGAV,ITGB4,MSN,HRAS,ARHGEF4
hsa04810	Regulation of actin cytoskeleton	0.000920561637155448	-6.99052659901639	215	120	0.0395778364116095	3032	6715	10163,71,54434,1793,5894,4627,22808,324,55740,28964,81624,4628,5881,5154,7409,1399,56924,55845,5216,5296,89846,54776,5290,8503,22801,5499,3687,8515,3694,7414,7074,4636,5159,1072,345456,2147,54961,91807,2249,2257,93408,1132,87,929,10627,2260,3630,2246,3689,2934,7454,3984,3645,4638,3681,3688,81,60,6093,103910,2245,81873,2335,4659,8874,3655,7410,1128,88,5305,10298,6714,10788,23396,2261,5880,3675,3696,23533,10092,9138,6548,5962,128239,3672,623,22800,1131,2264,5058,23191,56034,10451,2254,5829,6237,27006,5295,79837,23365,3845,5747,8394,26999,9564,10552,1729,5605,1956,10458,2248,2768,8817,26281,4660,3685,3691,4478,3265,50649	WASF2,ACTG1,SSH1,DOCK1,RAF1,MYH9,MRAS,APC,ENAH,GIT1,DIAPH3,MYH10,RAC3,PDGFA,VAV1,CRKL,PAK6,BRK1,PFN1,PIK3R2,FGD3,PPP1R12C,PIK3CA,PIK3R3,ITGA11,PPP1CA,ITGAX,ITGA10,ITGB6,VCL,TIAM1,MYL5,PDGFRB,CFL1,PFN3,F2,SSH3,MYLK3,FGF4,FGF12,MYL10,CHRM4,ACTN1,CD14,MYL12A,FGFR1,INS,FGF1,ITGB2,GSN,WAS,LIMK1,INSRR,MYLK,ITGAD,ITGB1,ACTN4,ACTB,ROCK1,MYL12B,FGD1,ARPC5L,FN1,PPP1R12A,ARHGEF7,ITGA6,VAV2,CHRM1,ACTN2,PIP4K2A,PAK4,SRC,IQGAP2,PIP5K1C,FGFR3,RAC2,ITGA3,ITGB8,PIK3R5,ARPC5,ARHGEF1,SLC9A1,RDX,IQGAP3,ITGA1,BDKRB1,RRAS2,CHRM3,FGFR4,PAK1,CYFIP1,PDGFC,VAV3,FGF9,PXN,RRAS,FGF22,PIK3R1,PIP4K2C,ARHGEF12,KRAS,PTK2,PIP5K1A,CYFIP2,BCAR1,ARPC1A,DIAPH1,MAP2K2,EGFR,BAIAP2,FGF3,GNA12,FGF18,FGF20,PPP1R12B,ITGAV,ITGB4,MSN,HRAS,ARHGEF4
hsa04141	Protein processing in endoplasmic reticulum	0.00135462846245555	-6.60422805969925	167	95	0.0313324538258575	3032	6715	5071,79748,7325,5589,5611,9451,55757,821,10961,10134,3303,6745,56605,56681,5034,9695,5887,55968,7326,10130,3306,54788,91445,55176,10802,578,56893,91319,468,9978,3326,3309,3312,118424,10299,7415,3310,29927,1650,3703,7466,1409,6400,6500,22926,10477,22824,8720,7323,10808,6396,80331,1388,23480,7186,3300,26270,9532,6748,10483,10956,9601,811,824,6184,85479,5601,10960,3320,201595,6048,7327,51360,10113,5609,267,11253,80267,6746,27102,10277,84447,7324,9709,3304,22872,79139,51128,23645,7322,64374,4217,10294,4780,1649	PARK2,LMAN1L,UBE2E2,PRKCSH,DNAJC3,EIF2AK3,UGGT2,CANX,ERP29,BCAP31,HSPA1A,SSR1,ERO1LB,SAR1A,P4HB,EDEM1,RAD23B,NSFL1C,UBE2G1,PDIA6,HSPA2,DNAJB12,RNF185,SEC61A2,SEC24A,BAK1,UBQLN4,DERL3,ATF4,RBX1,HSP90AB1,HSPA5,HSPA8,UBE2J2,MARCH6,VCP,HSPA6,SEC61A1,DDOST,STT3A,WFS1,CRYAA,SEL1L,SKP1,ATF6,UBE2E3,HSPA4L,MBTPS1,UBE2D3,HSPH1,SEC13,DNAJC5,ATF6B,SEC61G,TRAF2,DNAJB2,FBXO6,BAG2,SSR4,SEC23B,OS9,PDIA4,CALR,CAPN2,RPN1,DNAJC5B,MAPK9,LMAN2,HSP90AA1,STT3B,RNF5,UBE2G2,MBTPS2,PREB,MAP2K7,AMFR,MAN1B1,EDEM3,SSR2,EIF2AK1,UBE4B,SYVN1,UBE2E1,HERPUD1,HSPA1B,SEC31A,DERL1,SAR1B,PPP1R15A,UBE2D2,SIL1,MAP3K5,DNAJA2,NFE2L2,DDIT3
ko04141	Protein processing in endoplasmic reticulum	0.00135462846245555	-6.60422805969925	167	95	0.0313324538258575	3032	6715	5071,79748,7325,5589,5611,9451,55757,821,10961,10134,3303,6745,56605,56681,5034,9695,5887,55968,7326,10130,3306,54788,91445,55176,10802,578,56893,91319,468,9978,3326,3309,3312,118424,10299,7415,3310,29927,1650,3703,7466,1409,6400,6500,22926,10477,22824,8720,7323,10808,6396,80331,1388,23480,7186,3300,26270,9532,6748,10483,10956,9601,811,824,6184,85479,5601,10960,3320,201595,6048,7327,51360,10113,5609,267,11253,80267,6746,27102,10277,84447,7324,9709,3304,22872,79139,51128,23645,7322,64374,4217,10294,4780,1649	PARK2,LMAN1L,UBE2E2,PRKCSH,DNAJC3,EIF2AK3,UGGT2,CANX,ERP29,BCAP31,HSPA1A,SSR1,ERO1LB,SAR1A,P4HB,EDEM1,RAD23B,NSFL1C,UBE2G1,PDIA6,HSPA2,DNAJB12,RNF185,SEC61A2,SEC24A,BAK1,UBQLN4,DERL3,ATF4,RBX1,HSP90AB1,HSPA5,HSPA8,UBE2J2,MARCH6,VCP,HSPA6,SEC61A1,DDOST,STT3A,WFS1,CRYAA,SEL1L,SKP1,ATF6,UBE2E3,HSPA4L,MBTPS1,UBE2D3,HSPH1,SEC13,DNAJC5,ATF6B,SEC61G,TRAF2,DNAJB2,FBXO6,BAG2,SSR4,SEC23B,OS9,PDIA4,CALR,CAPN2,RPN1,DNAJC5B,MAPK9,LMAN2,HSP90AA1,STT3B,RNF5,UBE2G2,MBTPS2,PREB,MAP2K7,AMFR,MAN1B1,EDEM3,SSR2,EIF2AK1,UBE4B,SYVN1,UBE2E1,HERPUD1,HSPA1B,SEC31A,DERL1,SAR1B,PPP1R15A,UBE2D2,SIL1,MAP3K5,DNAJA2,NFE2L2,DDIT3
hsa04012	ErbB signaling pathway	0.00152233092156725	-6.48751261770488	88	54	0.0178100263852243	3032	6715	685,1839,399694,2475,5894,2064,9542,1026,5578,6714,10298,25759,27,25,1399,56924,3725,6464,53358,23533,4609,5336,5296,5601,5290,8503,2065,818,815,6199,5058,207,5609,4690,7039,5295,868,3845,5747,867,5605,1956,5335,817,10718,374,1978,10000,816,2932,6776,6198,3084,3265	BTC,HBEGF,SHC4,MTOR,RAF1,ERBB2,NRG2,CDKN1A,PRKCA,SRC,PAK4,SHC2,ABL2,ABL1,CRKL,PAK6,JUN,SHC1,SHC3,PIK3R5,MYC,PLCG2,PIK3R2,MAPK9,PIK3CA,PIK3R3,ERBB3,CAMK2G,CAMK2A,RPS6KB2,PAK1,AKT1,MAP2K7,NCK1,TGFA,PIK3R1,CBLB,KRAS,PTK2,CBL,MAP2K2,EGFR,PLCG1,CAMK2D,NRG3,AREG,EIF4EBP1,AKT3,CAMK2B,GSK3B,STAT5A,RPS6KB1,NRG1,HRAS
ko04012	ErbB signaling pathway	0.00152233092156725	-6.48751261770488	88	54	0.0178100263852243	3032	6715	685,1839,399694,2475,5894,2064,9542,1026,5578,6714,10298,25759,27,25,1399,56924,3725,6464,53358,23533,4609,5336,5296,5601,5290,8503,2065,818,815,6199,5058,207,5609,4690,7039,5295,868,3845,5747,867,5605,1956,5335,817,10718,374,1978,10000,816,2932,6776,6198,3084,3265	BTC,HBEGF,SHC4,MTOR,RAF1,ERBB2,NRG2,CDKN1A,PRKCA,SRC,PAK4,SHC2,ABL2,ABL1,CRKL,PAK6,JUN,SHC1,SHC3,PIK3R5,MYC,PLCG2,PIK3R2,MAPK9,PIK3CA,PIK3R3,ERBB3,CAMK2G,CAMK2A,RPS6KB2,PAK1,AKT1,MAP2K7,NCK1,TGFA,PIK3R1,CBLB,KRAS,PTK2,CBL,MAP2K2,EGFR,PLCG1,CAMK2D,NRG3,AREG,EIF4EBP1,AKT3,CAMK2B,GSK3B,STAT5A,RPS6KB1,NRG1,HRAS
hsa04310	Wnt signaling pathway	0.00201722014571022	-6.20603488084438	139	80	0.0263852242744063	3032	6715	23291,81839,11211,51701,324,1488,5578,5566,23002,5881,5331,595,1499,6477,57680,815,1856,5567,8321,9978,1454,7476,5613,4773,7481,57216,4772,7478,4088,83439,817,7475,8607,25805,8312,85407,2932,6500,5533,1855,8061,4089,8325,7472,85409,1452,8323,3725,56998,5880,4775,4609,80326,5601,896,6422,6885,89780,64321,5330,818,7484,7483,79718,144165,7477,6932,59343,6934,22943,54361,81029,816,5332,4776,27101,6907,7855,1487,8945	FBXW11,VANGL1,FZD10,NLK,APC,CTBP2,PRKCA,PRKACA,DAAM1,RAC3,PLCB3,CCND1,CTNNB1,SIAH1,CHD8,CAMK2A,DVL2,PRKACB,FZD1,RBX1,CSNK1E,WNT7A,PRKX,NFATC2,WNT11,VANGL2,NFATC1,WNT8A,SMAD3,TCF7L1,CAMK2D,WNT6,RUVBL1,BAMBI,AXIN1,NKD1,GSK3B,SKP1,PPP3CC,DVL1,FOSL1,SMAD4,FZD8,WNT2,NKD2,CSNK1A1,FZD6,JUN,CTNNBIP1,RAC2,NFATC3,MYC,WNT10A,MAPK9,CCND3,SFRP1,MAP3K7,WNT3A,SOX17,PLCB2,CAMK2G,WNT9B,WNT9A,TBL1XR1,PRICKLE1,WNT7B,TCF7,SENP2,TCF7L2,DKK1,WNT4,WNT5B,CAMK2B,PLCB4,NFATC4,CACYBP,TBL1X,FZD5,CTBP1,BTRC
ko04310	Wnt signaling pathway	0.00201722014571022	-6.20603488084438	139	80	0.0263852242744063	3032	6715	23291,81839,11211,51701,324,1488,5578,5566,23002,5881,5331,595,1499,6477,57680,815,1856,5567,8321,9978,1454,7476,5613,4773,7481,57216,4772,7478,4088,83439,817,7475,8607,25805,8312,85407,2932,6500,5533,1855,8061,4089,8325,7472,85409,1452,8323,3725,56998,5880,4775,4609,80326,5601,896,6422,6885,89780,64321,5330,818,7484,7483,79718,144165,7477,6932,59343,6934,22943,54361,81029,816,5332,4776,27101,6907,7855,1487,8945	FBXW11,VANGL1,FZD10,NLK,APC,CTBP2,PRKCA,PRKACA,DAAM1,RAC3,PLCB3,CCND1,CTNNB1,SIAH1,CHD8,CAMK2A,DVL2,PRKACB,FZD1,RBX1,CSNK1E,WNT7A,PRKX,NFATC2,WNT11,VANGL2,NFATC1,WNT8A,SMAD3,TCF7L1,CAMK2D,WNT6,RUVBL1,BAMBI,AXIN1,NKD1,GSK3B,SKP1,PPP3CC,DVL1,FOSL1,SMAD4,FZD8,WNT2,NKD2,CSNK1A1,FZD6,JUN,CTNNBIP1,RAC2,NFATC3,MYC,WNT10A,MAPK9,CCND3,SFRP1,MAP3K7,WNT3A,SOX17,PLCB2,CAMK2G,WNT9B,WNT9A,TBL1XR1,PRICKLE1,WNT7B,TCF7,SENP2,TCF7L2,DKK1,WNT4,WNT5B,CAMK2B,PLCB4,NFATC4,CACYBP,TBL1X,FZD5,CTBP1,BTRC
ko04370	VEGF signaling pathway	0.00232800142741018	-6.06274513596443	61	39	0.0128627968337731	3032	6715	5321,5894,8877,5578,1432,6714,5881,100137049,25759,5880,23533,5336,5296,5290,8503,5600,123745,5829,207,7867,9047,5295,4773,3845,5747,7422,5605,283748,9261,5743,5335,8605,255189,10000,5533,56848,3315,3265,6300	PLA2G4A,RAF1,SPHK1,PRKCA,MAPK14,SRC,RAC3,PLA2G4B,SHC2,RAC2,PIK3R5,PLCG2,PIK3R2,PIK3CA,PIK3R3,MAPK11,PLA2G4E,PXN,AKT1,MAPKAPK3,SH2D2A,PIK3R1,NFATC2,KRAS,PTK2,VEGFA,MAP2K2,PLA2G4D,MAPKAPK2,PTGS2,PLCG1,PLA2G4C,PLA2G4F,AKT3,PPP3CC,SPHK2,HSPB1,HRAS,MAPK12
hsa04370	VEGF signaling pathway	0.00232800142741018	-6.06274513596443	61	39	0.0128627968337731	3032	6715	5321,5894,8877,5578,1432,6714,5881,100137049,25759,5880,23533,5336,5296,5290,8503,5600,123745,5829,207,7867,9047,5295,4773,3845,5747,7422,5605,283748,9261,5743,5335,8605,255189,10000,5533,56848,3315,3265,6300	PLA2G4A,RAF1,SPHK1,PRKCA,MAPK14,SRC,RAC3,PLA2G4B,SHC2,RAC2,PIK3R5,PLCG2,PIK3R2,PIK3CA,PIK3R3,MAPK11,PLA2G4E,PXN,AKT1,MAPKAPK3,SH2D2A,PIK3R1,NFATC2,KRAS,PTK2,VEGFA,MAP2K2,PLA2G4D,MAPKAPK2,PTGS2,PLCG1,PLA2G4C,PLA2G4F,AKT3,PPP3CC,SPHK2,HSPB1,HRAS,MAPK12
hsa04916	Melanogenesis	0.0026081363851709	-5.94911934135757	101	60	0.0197889182058048	3032	6715	64764,8325,5894,11211,7472,7299,5578,5566,8323,5331,51806,1499,4157,80326,4286,112,109,89780,1385,5330,2771,3815,818,815,1856,5567,7484,7306,113,8321,148327,7483,7476,107,1906,90993,5613,3845,6932,7477,7481,5605,6934,7478,83439,817,54361,7475,111,114,81029,816,163688,5332,4254,2932,1855,7855,3265,810	CREB3L2,FZD8,RAF1,FZD10,WNT2,TYR,PRKCA,PRKACA,FZD6,PLCB3,CALML5,CTNNB1,MC1R,WNT10A,MITF,ADCY6,ADCY3,WNT3A,CREB1,PLCB2,GNAI2,KIT,CAMK2G,CAMK2A,DVL2,PRKACB,WNT9B,TYRP1,ADCY7,FZD1,CREB3L4,WNT9A,WNT7A,ADCY1,EDN1,CREB3L1,PRKX,KRAS,TCF7,WNT7B,WNT11,MAP2K2,TCF7L2,WNT8A,TCF7L1,CAMK2D,WNT4,WNT6,ADCY5,ADCY8,WNT5B,CAMK2B,CALML6,PLCB4,KITLG,GSK3B,DVL1,FZD5,HRAS,CALML3
ko04916	Melanogenesis	0.0026081363851709	-5.94911934135757	101	60	0.0197889182058048	3032	6715	64764,8325,5894,11211,7472,7299,5578,5566,8323,5331,51806,1499,4157,80326,4286,112,109,89780,1385,5330,2771,3815,818,815,1856,5567,7484,7306,113,8321,148327,7483,7476,107,1906,90993,5613,3845,6932,7477,7481,5605,6934,7478,83439,817,54361,7475,111,114,81029,816,163688,5332,4254,2932,1855,7855,3265,810	CREB3L2,FZD8,RAF1,FZD10,WNT2,TYR,PRKCA,PRKACA,FZD6,PLCB3,CALML5,CTNNB1,MC1R,WNT10A,MITF,ADCY6,ADCY3,WNT3A,CREB1,PLCB2,GNAI2,KIT,CAMK2G,CAMK2A,DVL2,PRKACB,WNT9B,TYRP1,ADCY7,FZD1,CREB3L4,WNT9A,WNT7A,ADCY1,EDN1,CREB3L1,PRKX,KRAS,TCF7,WNT7B,WNT11,MAP2K2,TCF7L2,WNT8A,TCF7L1,CAMK2D,WNT4,WNT6,ADCY5,ADCY8,WNT5B,CAMK2B,CALML6,PLCB4,KITLG,GSK3B,DVL1,FZD5,HRAS,CALML3
hsa04510	Focal adhesion	0.00285831096866183	-5.85752439900372	206	113	0.0372691292875989	3032	6715	1284,71,1793,5894,7148,2064,5578,329,5881,25759,2317,5154,7409,595,1399,56924,7791,3909,1499,6464,7448,53358,1280,5296,1289,54776,5290,8503,22801,5499,4233,8515,3694,7414,1311,4636,5159,2318,1292,91807,207,330,1277,93408,87,857,2316,7422,10627,5228,2534,2321,4638,3688,81,2932,3082,60,6093,64098,3918,103910,3911,399694,2335,4659,7094,3655,7410,88,7059,859,284217,10298,6714,1293,3914,23396,3725,824,5880,3675,3696,23533,2324,1291,5601,896,3913,63923,3672,5058,5170,56034,10451,5923,2889,5829,3915,7143,7058,5295,5747,9564,1729,1956,29780,10000,4660,7450,3685,3691,3265	COL4A2,ACTG1,DOCK1,RAF1,TNXB,ERBB2,PRKCA,BIRC2,RAC3,SHC2,FLNB,PDGFA,VAV1,CCND1,CRKL,PAK6,ZYX,LAMA3,CTNNB1,SHC1,VTN,SHC3,COL2A1,PIK3R2,COL5A1,PPP1R12C,PIK3CA,PIK3R3,ITGA11,PPP1CA,MET,ITGA10,ITGB6,VCL,COMP,MYL5,PDGFRB,FLNC,COL6A2,MYLK3,AKT1,BIRC3,COL1A1,MYL10,ACTN1,CAV1,FLNA,VEGFA,MYL12A,PGF,FYN,FLT1,MYLK,ITGB1,ACTN4,GSK3B,HGF,ACTB,ROCK1,PARVG,LAMC2,MYL12B,LAMA5,SHC4,FN1,PPP1R12A,TLN1,ITGA6,VAV2,ACTN2,THBS3,CAV3,LAMA1,PAK4,SRC,COL6A3,LAMB3,PIP5K1C,JUN,CAPN2,RAC2,ITGA3,ITGB8,PIK3R5,FLT4,COL6A1,MAPK9,CCND3,LAMB2,TNN,ITGA1,PAK1,PDPK1,PDGFC,VAV3,RASGRF1,RAPGEF1,PXN,LAMC1,TNR,THBS2,PIK3R1,PTK2,BCAR1,DIAPH1,EGFR,PARVB,AKT3,PPP1R12B,VWF,ITGAV,ITGB4,HRAS
ko04510	Focal adhesion	0.00285831096866183	-5.85752439900372	206	113	0.0372691292875989	3032	6715	1284,71,1793,5894,7148,2064,5578,329,5881,25759,2317,5154,7409,595,1399,56924,7791,3909,1499,6464,7448,53358,1280,5296,1289,54776,5290,8503,22801,5499,4233,8515,3694,7414,1311,4636,5159,2318,1292,91807,207,330,1277,93408,87,857,2316,7422,10627,5228,2534,2321,4638,3688,81,2932,3082,60,6093,64098,3918,103910,3911,399694,2335,4659,7094,3655,7410,88,7059,859,284217,10298,6714,1293,3914,23396,3725,824,5880,3675,3696,23533,2324,1291,5601,896,3913,63923,3672,5058,5170,56034,10451,5923,2889,5829,3915,7143,7058,5295,5747,9564,1729,1956,29780,10000,4660,7450,3685,3691,3265	COL4A2,ACTG1,DOCK1,RAF1,TNXB,ERBB2,PRKCA,BIRC2,RAC3,SHC2,FLNB,PDGFA,VAV1,CCND1,CRKL,PAK6,ZYX,LAMA3,CTNNB1,SHC1,VTN,SHC3,COL2A1,PIK3R2,COL5A1,PPP1R12C,PIK3CA,PIK3R3,ITGA11,PPP1CA,MET,ITGA10,ITGB6,VCL,COMP,MYL5,PDGFRB,FLNC,COL6A2,MYLK3,AKT1,BIRC3,COL1A1,MYL10,ACTN1,CAV1,FLNA,VEGFA,MYL12A,PGF,FYN,FLT1,MYLK,ITGB1,ACTN4,GSK3B,HGF,ACTB,ROCK1,PARVG,LAMC2,MYL12B,LAMA5,SHC4,FN1,PPP1R12A,TLN1,ITGA6,VAV2,ACTN2,THBS3,CAV3,LAMA1,PAK4,SRC,COL6A3,LAMB3,PIP5K1C,JUN,CAPN2,RAC2,ITGA3,ITGB8,PIK3R5,FLT4,COL6A1,MAPK9,CCND3,LAMB2,TNN,ITGA1,PAK1,PDPK1,PDGFC,VAV3,RASGRF1,RAPGEF1,PXN,LAMC1,TNR,THBS2,PIK3R1,PTK2,BCAR1,DIAPH1,EGFR,PARVB,AKT3,PPP1R12B,VWF,ITGAV,ITGB4,HRAS
hsa04910	Insulin signaling pathway	0.00345394789826544	-5.66823738383424	141	80	0.0263852242744063	3032	6715	5564,10580,7249,2475,5313,5894,5565,5506,8835,5566,25759,5139,1399,57521,8651,6464,53358,3551,5296,5290,2997,8503,5499,1977,5567,207,868,5257,5613,80201,5577,867,6009,3630,9021,53632,2645,1978,5590,2932,6198,5563,253314,399694,3636,5562,23265,79660,51763,5770,51806,23533,5601,6720,5105,2872,3101,5261,6199,5170,2889,5295,5575,2194,3845,92579,5605,8471,5834,90673,5792,51422,3643,10603,10000,163688,3099,3098,3265,810	PRKAB1,SORBS1,TSC2,MTOR,PKLR,RAF1,PRKAB2,PPP1R3A,SOCS2,PRKACA,SHC2,PDE3A,CRKL,RPTOR,SOCS1,SHC1,SHC3,IKBKB,PIK3R2,PIK3CA,GYS1,PIK3R3,PPP1CA,EIF4E,PRKACB,AKT1,CBLB,PHKB,PRKX,HKDC1,PRKAR2B,CBL,RHEB,INS,SOCS3,PRKAG3,GCK,EIF4EBP1,PRKCZ,GSK3B,RPS6KB1,PRKAA2,EIF4E1B,SHC4,INPPL1,PRKAA1,EXOC7,PPP1R3B,INPP5K,PTPN1,CALML5,PIK3R5,MAPK9,SREBF1,PCK1,MKNK2,HK3,PHKG2,RPS6KB2,PDPK1,RAPGEF1,PIK3R1,PRKAR1B,FASN,KRAS,G6PC3,MAP2K2,IRS4,PYGB,PPP1R3E,PTPRF,PRKAG2,INSR,SH2B2,AKT3,CALML6,HK2,HK1,HRAS,CALML3
ko04910	Insulin signaling pathway	0.00345394789826544	-5.66823738383424	141	80	0.0263852242744063	3032	6715	5564,10580,7249,2475,5313,5894,5565,5506,8835,5566,25759,5139,1399,57521,8651,6464,53358,3551,5296,5290,2997,8503,5499,1977,5567,207,868,5257,5613,80201,5577,867,6009,3630,9021,53632,2645,1978,5590,2932,6198,5563,253314,399694,3636,5562,23265,79660,51763,5770,51806,23533,5601,6720,5105,2872,3101,5261,6199,5170,2889,5295,5575,2194,3845,92579,5605,8471,5834,90673,5792,51422,3643,10603,10000,163688,3099,3098,3265,810	PRKAB1,SORBS1,TSC2,MTOR,PKLR,RAF1,PRKAB2,PPP1R3A,SOCS2,PRKACA,SHC2,PDE3A,CRKL,RPTOR,SOCS1,SHC1,SHC3,IKBKB,PIK3R2,PIK3CA,GYS1,PIK3R3,PPP1CA,EIF4E,PRKACB,AKT1,CBLB,PHKB,PRKX,HKDC1,PRKAR2B,CBL,RHEB,INS,SOCS3,PRKAG3,GCK,EIF4EBP1,PRKCZ,GSK3B,RPS6KB1,PRKAA2,EIF4E1B,SHC4,INPPL1,PRKAA1,EXOC7,PPP1R3B,INPP5K,PTPN1,CALML5,PIK3R5,MAPK9,SREBF1,PCK1,MKNK2,HK3,PHKG2,RPS6KB2,PDPK1,RAPGEF1,PIK3R1,PRKAR1B,FASN,KRAS,G6PC3,MAP2K2,IRS4,PYGB,PPP1R3E,PTPRF,PRKAG2,INSR,SH2B2,AKT3,CALML6,HK2,HK1,HRAS,CALML3
hsa04662	B cell receptor signaling pathway	0.00449988117146609	-5.40370428889538	72	44	0.0145118733509235	3032	6715	3636,4794,3635,5894,7410,4067,5881,8519,7409,3725,973,5880,4775,23533,933,3551,5336,4790,5296,5290,27071,8503,6850,10451,2213,207,5777,5295,974,10892,1380,4773,3845,2353,4772,5605,29760,8517,10000,4792,2932,5533,975,3265	INPPL1,NFKBIE,INPP5D,RAF1,VAV2,LYN,RAC3,IFITM1,VAV1,JUN,CD79A,RAC2,NFATC3,PIK3R5,CD22,IKBKB,PLCG2,NFKB1,PIK3R2,PIK3CA,DAPP1,PIK3R3,SYK,VAV3,FCGR2B,AKT1,PTPN6,PIK3R1,CD79B,MALT1,CR2,NFATC2,KRAS,FOS,NFATC1,MAP2K2,BLNK,IKBKG,AKT3,NFKBIA,GSK3B,PPP3CC,CD81,HRAS
ko04662	B cell receptor signaling pathway	0.00449988117146609	-5.40370428889538	72	44	0.0145118733509235	3032	6715	3636,4794,3635,5894,7410,4067,5881,8519,7409,3725,973,5880,4775,23533,933,3551,5336,4790,5296,5290,27071,8503,6850,10451,2213,207,5777,5295,974,10892,1380,4773,3845,2353,4772,5605,29760,8517,10000,4792,2932,5533,975,3265	INPPL1,NFKBIE,INPP5D,RAF1,VAV2,LYN,RAC3,IFITM1,VAV1,JUN,CD79A,RAC2,NFATC3,PIK3R5,CD22,IKBKB,PLCG2,NFKB1,PIK3R2,PIK3CA,DAPP1,PIK3R3,SYK,VAV3,FCGR2B,AKT1,PTPN6,PIK3R1,CD79B,MALT1,CR2,NFATC2,KRAS,FOS,NFATC1,MAP2K2,BLNK,IKBKG,AKT3,NFKBIA,GSK3B,PPP3CC,CD81,HRAS
hsa04918	Thyroid hormone synthesis	0.00449988117146609	-5.40370428889538	72	44	0.0145118733509235	3032	6715	64764,2878,1388,6528,9586,7173,821,5578,5566,433,9601,5331,389434,8458,112,109,1385,5330,1386,477,5567,113,148327,468,480,3309,107,90993,5613,481,405753,3710,476,486,7849,111,114,3708,5332,7038,50506,432,2876,478	CREB3L2,GPX3,ATF6B,SLC5A5,CREB5,TPO,CANX,PRKCA,PRKACA,ASGR2,PDIA4,PLCB3,IYD,TTF2,ADCY6,ADCY3,CREB1,PLCB2,ATF2,ATP1A2,PRKACB,ADCY7,CREB3L4,ATF4,ATP1A4,HSPA5,ADCY1,CREB3L1,PRKX,ATP1B1,DUOXA2,ITPR3,ATP1A1,FXYD2,PAX8,ADCY5,ADCY8,ITPR1,PLCB4,TG,DUOX2,ASGR1,GPX1,ATP1A3
ko04918	Thyroid hormone synthesis	0.00449988117146609	-5.40370428889538	72	44	0.0145118733509235	3032	6715	64764,2878,1388,6528,9586,7173,821,5578,5566,433,9601,5331,389434,8458,112,109,1385,5330,1386,477,5567,113,148327,468,480,3309,107,90993,5613,481,405753,3710,476,486,7849,111,114,3708,5332,7038,50506,432,2876,478	CREB3L2,GPX3,ATF6B,SLC5A5,CREB5,TPO,CANX,PRKCA,PRKACA,ASGR2,PDIA4,PLCB3,IYD,TTF2,ADCY6,ADCY3,CREB1,PLCB2,ATF2,ATP1A2,PRKACB,ADCY7,CREB3L4,ATF4,ATP1A4,HSPA5,ADCY1,CREB3L1,PRKX,ATP1B1,DUOXA2,ITPR3,ATP1A1,FXYD2,PAX8,ADCY5,ADCY8,ITPR1,PLCB4,TG,DUOX2,ASGR1,GPX1,ATP1A3
ko04261	Adrenergic signaling in cardiomyocytes	0.00574079509284815	-5.16015756032559	149	83	0.0273746701846966	3032	6715	64764,9254,5578,1432,5566,5331,786,5518,5296,5290,8503,109,779,5499,5521,10411,1386,477,148,815,5567,10369,113,3753,468,207,7170,492,27092,480,107,90993,5613,481,93589,5515,817,5529,476,5525,114,784,5522,7168,55844,5528,6300,7134,1388,9586,9252,147,51806,23533,6548,112,5600,1385,2771,5330,818,4634,148327,28227,7169,11069,5295,491,7171,6262,154,3784,5350,486,111,10000,816,163688,5332,7139,810,493,478	CREB3L2,CACNA2D2,PRKCA,MAPK14,PRKACA,PLCB3,CACNG1,PPP2R1A,PIK3R2,PIK3CA,PIK3R3,ADCY3,CACNA1S,PPP1CA,PPP2R2B,RAPGEF3,ATF2,ATP1A2,ADRA1A,CAMK2A,PRKACB,CACNG2,ADCY7,KCNE1,ATF4,AKT1,TPM3,ATP2B3,CACNG4,ATP1A4,ADCY1,CREB3L1,PRKX,ATP1B1,CACNA2D4,PPP2CA,CAMK2D,PPP2R5E,ATP1A1,PPP2R5A,ADCY8,CACNB3,PPP2R2C,TPM1,PPP2R2D,PPP2R5D,MAPK12,TNNC1,ATF6B,CREB5,RPS6KA5,ADRA1B,CALML5,PIK3R5,SLC9A1,ADCY6,MAPK11,CREB1,GNAI2,PLCB2,CAMK2G,MYL3,CREB3L4,PPP2R3B,TPM2,RAPGEF4,PIK3R1,ATP2B2,TPM4,RYR2,ADRB2,KCNQ1,PLN,FXYD2,ADCY5,AKT3,CAMK2B,CALML6,PLCB4,TNNT2,CALML3,ATP2B4,ATP1A3
hsa04261	Adrenergic signaling in cardiomyocytes	0.00574079509284815	-5.16015756032559	149	83	0.0273746701846966	3032	6715	64764,9254,5578,1432,5566,5331,786,5518,5296,5290,8503,109,779,5499,5521,10411,1386,477,148,815,5567,10369,113,3753,468,207,7170,492,27092,480,107,90993,5613,481,93589,5515,817,5529,476,5525,114,784,5522,7168,55844,5528,6300,7134,1388,9586,9252,147,51806,23533,6548,112,5600,1385,2771,5330,818,4634,148327,28227,7169,11069,5295,491,7171,6262,154,3784,5350,486,111,10000,816,163688,5332,7139,810,493,478	CREB3L2,CACNA2D2,PRKCA,MAPK14,PRKACA,PLCB3,CACNG1,PPP2R1A,PIK3R2,PIK3CA,PIK3R3,ADCY3,CACNA1S,PPP1CA,PPP2R2B,RAPGEF3,ATF2,ATP1A2,ADRA1A,CAMK2A,PRKACB,CACNG2,ADCY7,KCNE1,ATF4,AKT1,TPM3,ATP2B3,CACNG4,ATP1A4,ADCY1,CREB3L1,PRKX,ATP1B1,CACNA2D4,PPP2CA,CAMK2D,PPP2R5E,ATP1A1,PPP2R5A,ADCY8,CACNB3,PPP2R2C,TPM1,PPP2R2D,PPP2R5D,MAPK12,TNNC1,ATF6B,CREB5,RPS6KA5,ADRA1B,CALML5,PIK3R5,SLC9A1,ADCY6,MAPK11,CREB1,GNAI2,PLCB2,CAMK2G,MYL3,CREB3L4,PPP2R3B,TPM2,RAPGEF4,PIK3R1,ATP2B2,TPM4,RYR2,ADRB2,KCNQ1,PLN,FXYD2,ADCY5,AKT3,CAMK2B,CALML6,PLCB4,TNNT2,CALML3,ATP2B4,ATP1A3
ko04660	T cell receptor signaling pathway	0.00648739332881208	-5.03789447319763	104	60	0.0197889182058048	3032	6715	920,4794,5894,1326,7410,3565,3937,1432,29851,10298,7409,56924,3725,5133,4775,23533,919,3551,4790,5296,5601,1739,5290,8503,5600,6885,9020,5058,5170,27040,10451,207,5609,4690,5777,1019,5295,10892,868,4773,3845,3586,1437,867,4772,2353,5605,5788,925,5335,8517,2534,10000,4792,2932,5533,3265,940,3567,6300	CD4,NFKBIE,RAF1,MAP3K8,VAV2,IL4,LCP2,MAPK14,ICOS,PAK4,VAV1,PAK6,JUN,PDCD1,NFATC3,PIK3R5,CD247,IKBKB,NFKB1,PIK3R2,MAPK9,DLG1,PIK3CA,PIK3R3,MAPK11,MAP3K7,MAP3K14,PAK1,PDPK1,LAT,VAV3,AKT1,MAP2K7,NCK1,PTPN6,CDK4,PIK3R1,MALT1,CBLB,NFATC2,KRAS,IL10,CSF2,CBL,NFATC1,FOS,MAP2K2,PTPRC,CD8A,PLCG1,IKBKG,FYN,AKT3,NFKBIA,GSK3B,PPP3CC,HRAS,CD28,IL5,MAPK12
hsa04660	T cell receptor signaling pathway	0.00648739332881208	-5.03789447319763	104	60	0.0197889182058048	3032	6715	920,4794,5894,1326,7410,3565,3937,1432,29851,10298,7409,56924,3725,5133,4775,23533,919,3551,4790,5296,5601,1739,5290,8503,5600,6885,9020,5058,5170,27040,10451,207,5609,4690,5777,1019,5295,10892,868,4773,3845,3586,1437,867,4772,2353,5605,5788,925,5335,8517,2534,10000,4792,2932,5533,3265,940,3567,6300	CD4,NFKBIE,RAF1,MAP3K8,VAV2,IL4,LCP2,MAPK14,ICOS,PAK4,VAV1,PAK6,JUN,PDCD1,NFATC3,PIK3R5,CD247,IKBKB,NFKB1,PIK3R2,MAPK9,DLG1,PIK3CA,PIK3R3,MAPK11,MAP3K7,MAP3K14,PAK1,PDPK1,LAT,VAV3,AKT1,MAP2K7,NCK1,PTPN6,CDK4,PIK3R1,MALT1,CBLB,NFATC2,KRAS,IL10,CSF2,CBL,NFATC1,FOS,MAP2K2,PTPRC,CD8A,PLCG1,IKBKG,FYN,AKT3,NFKBIA,GSK3B,PPP3CC,HRAS,CD28,IL5,MAPK12
ko04668	TNF signaling pathway	0.00670296505149348	-5.00520530548035	110	63	0.020778364116095	3032	6715	4318,64764,1388,3600,7186,1326,8737,9586,1432,9252,329,5606,3383,8837,3725,182,23533,3726,3551,4790,5296,5601,5290,4323,8503,8986,5600,1385,6885,9020,1386,3976,148327,468,207,330,7128,5609,6364,5295,1906,90993,1437,2353,8772,9021,355,1051,5743,8517,7185,23118,10059,1435,10000,4792,7132,64127,7187,4217,192111,7188,6300	MMP9,CREB3L2,ATF6B,IL15,TRAF2,MAP3K8,RIPK1,CREB5,MAPK14,RPS6KA5,BIRC2,MAP2K3,ICAM1,CFLAR,JUN,JAG1,PIK3R5,JUNB,IKBKB,NFKB1,PIK3R2,MAPK9,PIK3CA,MMP14,PIK3R3,RPS6KA4,MAPK11,CREB1,MAP3K7,MAP3K14,ATF2,LIF,CREB3L4,ATF4,AKT1,BIRC3,TNFAIP3,MAP2K7,CCL20,PIK3R1,EDN1,CREB3L1,CSF2,FOS,FADD,SOCS3,FAS,CEBPB,PTGS2,IKBKG,TRAF1,TAB2,DNM1L,CSF1,AKT3,NFKBIA,TNFRSF1A,NOD2,TRAF3,MAP3K5,PGAM5,TRAF5,MAPK12
hsa04668	TNF signaling pathway	0.00670296505149348	-5.00520530548035	110	63	0.020778364116095	3032	6715	4318,64764,1388,3600,7186,1326,8737,9586,1432,9252,329,5606,3383,8837,3725,182,23533,3726,3551,4790,5296,5601,5290,4323,8503,8986,5600,1385,6885,9020,1386,3976,148327,468,207,330,7128,5609,6364,5295,1906,90993,1437,2353,8772,9021,355,1051,5743,8517,7185,23118,10059,1435,10000,4792,7132,64127,7187,4217,192111,7188,6300	MMP9,CREB3L2,ATF6B,IL15,TRAF2,MAP3K8,RIPK1,CREB5,MAPK14,RPS6KA5,BIRC2,MAP2K3,ICAM1,CFLAR,JUN,JAG1,PIK3R5,JUNB,IKBKB,NFKB1,PIK3R2,MAPK9,PIK3CA,MMP14,PIK3R3,RPS6KA4,MAPK11,CREB1,MAP3K7,MAP3K14,ATF2,LIF,CREB3L4,ATF4,AKT1,BIRC3,TNFAIP3,MAP2K7,CCL20,PIK3R1,EDN1,CREB3L1,CSF2,FOS,FADD,SOCS3,FAS,CEBPB,PTGS2,IKBKG,TRAF1,TAB2,DNM1L,CSF1,AKT3,NFKBIA,TNFRSF1A,NOD2,TRAF3,MAP3K5,PGAM5,TRAF5,MAPK12
ko00520	Amino sugar and nucleotide sugar metabolism	0.00748941250193892	-4.89426492218776	47	30	0.00989445910290238	3032	6715	5236,2584,55907,9945,197258,7360,7264,10007,7358,5973,80201,80896,2585,5373,29926,80146,5372,2645,6675,3099,29925,3098,51706,2821,2762,140838,1118,3101,1727,2582	PGM1,GALK1,CMAS,GFPT2,FUK,UGP2,TSTA3,GNPDA1,UGDH,RENBP,HKDC1,NPL,GALK2,PMM2,GMPPA,UXS1,PMM1,GCK,UAP1,HK2,GMPPB,HK1,CYB5R1,GPI,GMDS,NANP,CHIT1,HK3,CYB5R3,GALE
hsa00520	Amino sugar and nucleotide sugar metabolism	0.00748941250193892	-4.89426492218776	47	30	0.00989445910290238	3032	6715	5236,55907,9945,2584,197258,7360,7264,10007,7358,5973,80201,80896,2585,5373,29926,80146,5372,2645,6675,3099,29925,51706,3098,2821,1118,140838,2762,3101,1727,2582	PGM1,CMAS,GFPT2,GALK1,FUK,UGP2,TSTA3,GNPDA1,UGDH,RENBP,HKDC1,NPL,GALK2,PMM2,GMPPA,UXS1,PMM1,GCK,UAP1,HK2,GMPPB,CYB5R1,HK1,GPI,CHIT1,NANP,GMDS,HK3,CYB5R3,GALE
hsa00564	Glycerophospholipid metabolism	0.007878431587029	-4.84362643210194	91	53	0.0174802110817942	3032	6715	5321,8760,8525,1609,1606,55500,8527,10162,55224,5338,56894,81579,1120,64900,10423,151056,100137049,23761,23175,1040,2819,8611,375775,122618,23171,79888,8398,123745,85465,150763,9926,9489,56895,8612,8399,79143,3931,283748,8605,10555,255189,10400,9162,8443,1103,254531,154141,5337,57678,129642,56994,43,56985	PLA2G4A,CDS2,DGKZ,DGKQ,DGKA,ETNK1,DGKD,LPCAT3,ETNK2,PLD2,AGPAT3,PLA2G12A,CHKB,LPIN3,CDIPT,PLB1,PLA2G4B,PISD,LPIN1,CDS1,GPD1,PPAP2A,PNPLA7,PLD4,GPD1L,LPCAT1,PLA2G6,PLA2G4E,EPT1,GPAT2,LPGAT1,PGS1,AGPAT4,PPAP2C,PLA2G10,MBOAT7,LCAT,PLA2G4D,PLA2G4C,AGPAT2,PLA2G4F,PEMT,DGKI,GNPAT,CHAT,LPCAT4,MBOAT1,PLD1,GPAM,MBOAT2,CHPT1,ACHE,ADPRM
ko00564	Glycerophospholipid metabolism	0.007878431587029	-4.84362643210194	91	53	0.0174802110817942	3032	6715	5321,8760,8525,1609,1606,55500,5338,56894,8527,10162,55224,81579,1120,64900,10423,151056,100137049,23761,23175,1040,2819,8611,375775,122618,23171,79888,8398,123745,85465,56895,150763,9926,9489,8612,8399,79143,283748,3931,8605,10555,255189,10400,1103,9162,8443,254531,154141,57678,5337,129642,56994,56985,43	PLA2G4A,CDS2,DGKZ,DGKQ,DGKA,ETNK1,PLD2,AGPAT3,DGKD,LPCAT3,ETNK2,PLA2G12A,CHKB,LPIN3,CDIPT,PLB1,PLA2G4B,PISD,LPIN1,CDS1,GPD1,PPAP2A,PNPLA7,PLD4,GPD1L,LPCAT1,PLA2G6,PLA2G4E,EPT1,AGPAT4,GPAT2,LPGAT1,PGS1,PPAP2C,PLA2G10,MBOAT7,PLA2G4D,LCAT,PLA2G4C,AGPAT2,PLA2G4F,PEMT,CHAT,DGKI,GNPAT,LPCAT4,MBOAT1,GPAM,PLD1,MBOAT2,CHPT1,ADPRM,ACHE
hsa04725	Cholinergic synapse	0.00882580605971993	-4.73007534212197	113	64	0.0211081794195251	3032	6715	64764,3763,2782,5578,5566,2783,5331,5296,5290,8503,109,779,815,5567,113,1139,468,207,2788,107,8973,90993,5613,1132,3710,3785,817,2534,59345,114,774,1141,1128,9586,23533,2793,112,51764,3717,1385,2771,5330,1131,818,3768,148327,3786,3759,773,5295,2786,3845,3784,2353,2767,1137,10000,816,111,3708,1103,5332,43,3265	CREB3L2,KCNJ6,GNB1,PRKCA,PRKACA,GNB2,PLCB3,PIK3R2,PIK3CA,PIK3R3,ADCY3,CACNA1S,CAMK2A,PRKACB,ADCY7,CHRNA7,ATF4,AKT1,GNG7,ADCY1,CHRNA6,CREB3L1,PRKX,CHRM4,ITPR3,KCNQ2,CAMK2D,FYN,GNB4,ADCY8,CACNA1B,CHRNB2,CHRM1,CREB5,PIK3R5,GNGT2,ADCY6,GNG13,JAK2,CREB1,GNAI2,PLCB2,CHRM3,CAMK2G,KCNJ12,CREB3L4,KCNQ3,KCNJ2,CACNA1A,PIK3R1,GNG4,KRAS,KCNQ1,FOS,GNA11,CHRNA4,AKT3,CAMK2B,ADCY5,ITPR1,CHAT,PLCB4,ACHE,HRAS
hsa05222	Small cell lung cancer	0.010135902953981	-4.59167141039933	86	50	0.016490765171504	3032	6715	9134,7189,4149,1284,2335,7186,3655,6256,54205,284217,329,898,3914,595,3909,3675,23533,4609,3551,4790,5296,5290,1163,8503,3913,2272,1164,6258,207,330,3915,1019,5295,1871,5747,5743,8517,7185,10000,4792,3688,7187,3685,317,7188,1870,9618,4843,3918,3911	CCNE2,TRAF6,MAX,COL4A2,FN1,TRAF2,ITGA6,RXRA,CYCS,LAMA1,BIRC2,CCNE1,LAMB3,CCND1,LAMA3,ITGA3,PIK3R5,MYC,IKBKB,NFKB1,PIK3R2,PIK3CA,CKS1B,PIK3R3,LAMB2,FHIT,CKS2,RXRG,AKT1,BIRC3,LAMC1,CDK4,PIK3R1,E2F3,PTK2,PTGS2,IKBKG,TRAF1,AKT3,NFKBIA,ITGB1,TRAF3,ITGAV,APAF1,TRAF5,E2F2,TRAF4,NOS2,LAMC2,LAMA5
ko05222	Small cell lung cancer	0.010135902953981	-4.59167141039933	86	50	0.016490765171504	3032	6715	9134,7189,4149,1284,2335,7186,3655,6256,54205,284217,329,898,3914,595,3909,3675,23533,4609,3551,4790,5296,5290,1163,8503,3913,2272,1164,6258,207,330,3915,1019,5295,1871,5747,5743,8517,7185,10000,4792,3688,7187,3685,317,7188,1870,9618,4843,3918,3911	CCNE2,TRAF6,MAX,COL4A2,FN1,TRAF2,ITGA6,RXRA,CYCS,LAMA1,BIRC2,CCNE1,LAMB3,CCND1,LAMA3,ITGA3,PIK3R5,MYC,IKBKB,NFKB1,PIK3R2,PIK3CA,CKS1B,PIK3R3,LAMB2,FHIT,CKS2,RXRG,AKT1,BIRC3,LAMC1,CDK4,PIK3R1,E2F3,PTK2,PTGS2,IKBKG,TRAF1,AKT3,NFKBIA,ITGB1,TRAF3,ITGAV,APAF1,TRAF5,E2F2,TRAF4,NOS2,LAMC2,LAMA5
hsa00562	Inositol phosphate metabolism	0.0104250912485136	-4.56353975848056	61	37	0.0122031662269129	3032	6715	3707,4534,3636,89869,4329,3635,113026,51477,10423,8867,5305,23396,5331,56623,51763,64768,3631,5298,3632,54928,5336,5290,8871,5330,3613,3612,5333,79837,8394,5286,55361,5335,55300,55586,8821,5332,5287	ITPKB,MTM1,INPPL1,PLCZ1,ALDH6A1,INPP5D,PLCD3,ISYNA1,CDIPT,SYNJ1,PIP4K2A,PIP5K1C,PLCB3,INPP5E,INPP5K,IPPK,INPP4A,PI4KB,INPP5A,IMPAD1,PLCG2,PIK3CA,SYNJ2,PLCB2,IMPA2,IMPA1,PLCD1,PIP4K2C,PIP5K1A,PIK3C2A,PI4K2A,PLCG1,PI4K2B,MIOX,INPP4B,PLCB4,PIK3C2B
ko00562	Inositol phosphate metabolism	0.0104250912485136	-4.56353975848056	61	37	0.0122031662269129	3032	6715	3707,4534,3636,89869,4329,3635,51477,113026,10423,8867,5305,23396,5331,56623,51763,64768,3631,5298,3632,54928,5336,5290,8871,5330,3613,3612,5333,79837,8394,5286,55361,5335,55300,55586,8821,5332,5287	ITPKB,MTM1,INPPL1,PLCZ1,ALDH6A1,INPP5D,ISYNA1,PLCD3,CDIPT,SYNJ1,PIP4K2A,PIP5K1C,PLCB3,INPP5E,INPP5K,IPPK,INPP4A,PI4KB,INPP5A,IMPAD1,PLCG2,PIK3CA,SYNJ2,PLCB2,IMPA2,IMPA1,PLCD1,PIP4K2C,PIP5K1A,PIK3C2A,PI4K2A,PLCG1,PI4K2B,MIOX,INPP4B,PLCB4,PIK3C2B
ko04912	GnRH signaling pathway	0.0105439390920591	-4.55220407778846	92	53	0.0174802110817942	3032	6715	5321,1839,5894,5338,5578,1432,5566,6714,100137049,5606,5331,3725,51806,5580,5601,4313,4323,112,109,5600,779,5330,818,815,5567,123745,113,4215,468,5609,107,5613,3845,3710,5605,2767,1956,283748,817,8605,255189,111,114,816,3708,3972,163688,2185,5332,5337,3265,810,6300	PLA2G4A,HBEGF,RAF1,PLD2,PRKCA,MAPK14,PRKACA,SRC,PLA2G4B,MAP2K3,PLCB3,JUN,CALML5,PRKCD,MAPK9,MMP2,MMP14,ADCY6,ADCY3,MAPK11,CACNA1S,PLCB2,CAMK2G,CAMK2A,PRKACB,PLA2G4E,ADCY7,MAP3K3,ATF4,MAP2K7,ADCY1,PRKX,KRAS,ITPR3,MAP2K2,GNA11,EGFR,PLA2G4D,CAMK2D,PLA2G4C,PLA2G4F,ADCY5,ADCY8,CAMK2B,ITPR1,LHB,CALML6,PTK2B,PLCB4,PLD1,HRAS,CALML3,MAPK12
hsa04912	GnRH signaling pathway	0.0105439390920591	-4.55220407778846	92	53	0.0174802110817942	3032	6715	5321,1839,5894,5338,5578,1432,5566,6714,100137049,5606,5331,3725,51806,5580,5601,4313,4323,112,109,5600,779,5330,818,815,5567,123745,113,4215,468,5609,107,5613,3845,3710,5605,2767,1956,283748,817,8605,255189,111,114,816,3708,3972,163688,2185,5332,5337,3265,810,6300	PLA2G4A,HBEGF,RAF1,PLD2,PRKCA,MAPK14,PRKACA,SRC,PLA2G4B,MAP2K3,PLCB3,JUN,CALML5,PRKCD,MAPK9,MMP2,MMP14,ADCY6,ADCY3,MAPK11,CACNA1S,PLCB2,CAMK2G,CAMK2A,PRKACB,PLA2G4E,ADCY7,MAP3K3,ATF4,MAP2K7,ADCY1,PRKX,KRAS,ITPR3,MAP2K2,GNA11,EGFR,PLA2G4D,CAMK2D,PLA2G4C,PLA2G4F,ADCY5,ADCY8,CAMK2B,ITPR1,LHB,CALML6,PTK2B,PLCB4,PLD1,HRAS,CALML3,MAPK12
hsa04015	Rap1 signaling pathway	0.0113373722159263	-4.479650734526	213	113	0.0372691292875989	3032	6715	3397,84552,71,5894,22808,9002,3937,5578,1432,23566,5881,84612,5606,5331,5154,1399,57568,1499,57121,999,5899,5216,5296,5290,8503,109,10411,4233,3815,7074,5159,345456,113,27040,207,2249,2257,107,83593,7422,2260,3630,2246,3689,5898,5228,5335,1969,1945,114,2321,5590,3688,4254,1946,3082,60,10636,5909,284,56288,6300,9170,64411,7094,7410,5900,5028,136,51735,6714,2261,5880,51806,23533,2324,112,5600,5330,2771,9855,2264,56034,2254,2889,116984,6237,27006,9693,11069,5295,1944,2902,3845,9564,4804,5605,1956,2248,3643,111,1435,10000,8817,26281,116985,163688,5332,51378,1942,3265,810,1436	ID1,PARD6G,ACTG1,RAF1,MRAS,F2RL3,LCP2,PRKCA,MAPK14,LPAR3,RAC3,PARD6B,MAP2K3,PLCB3,PDGFA,CRKL,SIPA1L2,CTNNB1,LPAR5,CDH1,RALB,PFN1,PIK3R2,PIK3CA,PIK3R3,ADCY3,RAPGEF3,MET,KIT,TIAM1,PDGFRB,PFN3,ADCY7,LAT,AKT1,FGF4,FGF12,ADCY1,RASSF5,VEGFA,FGFR1,INS,FGF1,ITGB2,RALA,PGF,PLCG1,EPHA2,EFNA4,ADCY8,FLT1,PRKCZ,ITGB1,KITLG,EFNA5,HGF,ACTB,RGS14,RAP1GAP,ANGPT1,PARD3,MAPK12,LPAR2,ARAP3,TLN1,VAV2,RALGDS,P2RY1,ADORA2B,RAPGEF6,SRC,FGFR3,RAC2,CALML5,PIK3R5,FLT4,ADCY6,MAPK11,PLCB2,GNAI2,FARP2,FGFR4,PDGFC,FGF9,RAPGEF1,ARAP2,RRAS,FGF22,RAPGEF2,RAPGEF4,PIK3R1,EFNA3,GRIN1,KRAS,BCAR1,NGFR,MAP2K2,EGFR,FGF3,INSR,ADCY5,CSF1,AKT3,FGF18,FGF20,ARAP1,CALML6,PLCB4,ANGPT4,EFNA1,HRAS,CALML3,CSF1R
ko04015	Rap1 signaling pathway	0.0113373722159263	-4.479650734526	213	113	0.0372691292875989	3032	6715	3397,84552,71,5894,22808,9002,3937,5578,1432,23566,5881,84612,5606,5331,5154,1399,57568,1499,57121,999,5899,5216,5296,5290,8503,109,10411,4233,3815,7074,5159,345456,113,27040,207,2249,2257,107,83593,7422,2260,3630,2246,3689,5898,5228,5335,1969,1945,114,2321,5590,3688,4254,1946,3082,60,10636,5909,284,56288,6300,9170,64411,7094,7410,5900,5028,136,51735,6714,2261,5880,51806,23533,2324,112,5600,5330,2771,9855,2264,56034,2254,2889,116984,6237,27006,9693,11069,5295,1944,2902,3845,9564,4804,5605,1956,2248,3643,111,1435,10000,8817,26281,116985,163688,5332,51378,1942,3265,810,1436	ID1,PARD6G,ACTG1,RAF1,MRAS,F2RL3,LCP2,PRKCA,MAPK14,LPAR3,RAC3,PARD6B,MAP2K3,PLCB3,PDGFA,CRKL,SIPA1L2,CTNNB1,LPAR5,CDH1,RALB,PFN1,PIK3R2,PIK3CA,PIK3R3,ADCY3,RAPGEF3,MET,KIT,TIAM1,PDGFRB,PFN3,ADCY7,LAT,AKT1,FGF4,FGF12,ADCY1,RASSF5,VEGFA,FGFR1,INS,FGF1,ITGB2,RALA,PGF,PLCG1,EPHA2,EFNA4,ADCY8,FLT1,PRKCZ,ITGB1,KITLG,EFNA5,HGF,ACTB,RGS14,RAP1GAP,ANGPT1,PARD3,MAPK12,LPAR2,ARAP3,TLN1,VAV2,RALGDS,P2RY1,ADORA2B,RAPGEF6,SRC,FGFR3,RAC2,CALML5,PIK3R5,FLT4,ADCY6,MAPK11,PLCB2,GNAI2,FARP2,FGFR4,PDGFC,FGF9,RAPGEF1,ARAP2,RRAS,FGF22,RAPGEF2,RAPGEF4,PIK3R1,EFNA3,GRIN1,KRAS,BCAR1,NGFR,MAP2K2,EGFR,FGF3,INSR,ADCY5,CSF1,AKT3,FGF18,FGF20,ARAP1,CALML6,PLCB4,ANGPT4,EFNA1,HRAS,CALML3,CSF1R
ko04930	Type II diabetes mellitus	0.0114488248851298	-4.46986818436839	48	30	0.00989445910290238	3032	6715	2475,5313,777,773,5295,8835,80201,5315,8471,3630,9021,6833,3643,2645,3651,8651,23533,5580,3551,5601,5296,3099,5290,5590,8503,389692,3767,3098,774,3101	MTOR,PKLR,CACNA1E,CACNA1A,PIK3R1,SOCS2,HKDC1,PKM,IRS4,INS,SOCS3,ABCC8,INSR,GCK,PDX1,SOCS1,PIK3R5,PRKCD,IKBKB,MAPK9,PIK3R2,HK2,PIK3CA,PRKCZ,PIK3R3,MAFA,KCNJ11,HK1,CACNA1B,HK3
hsa04930	Type II diabetes mellitus	0.0114488248851298	-4.46986818436839	48	30	0.00989445910290238	3032	6715	2475,5313,777,773,5295,8835,80201,5315,8471,3630,9021,6833,3643,2645,3651,8651,23533,5580,3551,5601,5296,3099,5290,5590,8503,389692,3767,3098,774,3101	MTOR,PKLR,CACNA1E,CACNA1A,PIK3R1,SOCS2,HKDC1,PKM,IRS4,INS,SOCS3,ABCC8,INSR,GCK,PDX1,SOCS1,PIK3R5,PRKCD,IKBKB,MAPK9,PIK3R2,HK2,PIK3CA,PRKCZ,PIK3R3,MAFA,KCNJ11,HK1,CACNA1B,HK3
hsa04142	Lysosome	0.0114963781923387	-4.46572323301352	122	68	0.0224274406332454	3032	6715	3916,2548,8722,537,10947,23457,8120,410,533,8763,10053,20,8907,3373,1212,5641,9741,4668,175,2760,27074,8905,1510,10717,6609,26503,3988,26985,4864,10312,79158,4669,7805,527,1201,26088,768239,4126,1508,8943,285362,4125,4074,1520,130340,1509,51606,3425,1512,9114,3482,11154,2581,2629,10577,9179,138050,1203,1513,4758,3423,84572,6448,1497,1515,1211,5660,411	LAMP1,GAA,CTSF,ATP6AP1,AP3M2,ABCB9,AP3B2,ARSA,ATP6V0B,CD164,AP1M2,ABCA2,AP1M1,HYAL1,CLTB,LGMN,LAPTM4A,NAGA,AGA,GM2A,LAMP3,AP1S2,CTSE,AP4B1,SMPD1,SLC17A5,LIPA,AP3M1,NPC1,TCIRG1,GNPTAB,NAGLU,LAPTM5,ATP6V0C,CLN3,GGA1,PSAPL1,MANBA,CTSB,AP3D1,SUMF1,MAN2B1,M6PR,CTSS,AP1S3,CTSD,ATP6V1H,IDUA,CTSH,ATP6V0D1,IGF2R,AP4S1,GALC,GBA,NPC2,AP4M1,HGSNAT,CLN5,CTSK,NEU1,IDS,GNPTG,SGSH,CTNS,CTSV,CLTA,PSAP,ARSB
ko04142	Lysosome	0.0114963781923387	-4.46572323301352	122	68	0.0224274406332454	3032	6715	3916,2548,8722,537,10947,23457,8120,410,533,8763,10053,20,8907,3373,1212,5641,9741,4668,175,2760,27074,8905,1510,10717,6609,26503,3988,26985,4864,10312,79158,4669,7805,527,1201,26088,768239,4126,1508,8943,285362,4125,4074,1520,130340,1509,51606,3425,1512,9114,3482,11154,2581,2629,10577,9179,138050,1203,1513,4758,3423,84572,6448,1497,1515,1211,5660,411	LAMP1,GAA,CTSF,ATP6AP1,AP3M2,ABCB9,AP3B2,ARSA,ATP6V0B,CD164,AP1M2,ABCA2,AP1M1,HYAL1,CLTB,LGMN,LAPTM4A,NAGA,AGA,GM2A,LAMP3,AP1S2,CTSE,AP4B1,SMPD1,SLC17A5,LIPA,AP3M1,NPC1,TCIRG1,GNPTAB,NAGLU,LAPTM5,ATP6V0C,CLN3,GGA1,PSAPL1,MANBA,CTSB,AP3D1,SUMF1,MAN2B1,M6PR,CTSS,AP1S3,CTSD,ATP6V1H,IDUA,CTSH,ATP6V0D1,IGF2R,AP4S1,GALC,GBA,NPC2,AP4M1,HGSNAT,CLN5,CTSK,NEU1,IDS,GNPTG,SGSH,CTNS,CTSV,CLTA,PSAP,ARSB
hsa04380	Osteoclast differentiation	0.0115187874742473	-4.46377588322557	132	73	0.0240765171503958	3032	6715	7189,1540,2355,3937,1432,4688,353514,8651,2209,3551,5336,4286,4790,5296,2354,5290,8503,5971,9103,4791,6688,55423,4689,207,4773,4772,7297,9021,8517,2534,23118,7132,5533,4982,79168,8061,6300,7186,7046,7042,7048,140885,3725,8878,23533,3726,5601,653361,10379,5600,9020,6885,1385,6850,8792,2213,3460,5609,5295,2274,3454,23547,1513,2353,29760,2214,3554,10000,1435,4792,10990,2212,1436	TRAF6,CYLD,FOSL2,LCP2,MAPK14,NCF2,LILRA5,SOCS1,FCGR1A,IKBKB,PLCG2,MITF,NFKB1,PIK3R2,FOSB,PIK3CA,PIK3R3,RELB,FCGR2C,NFKB2,SPI1,SIRPG,NCF4,AKT1,NFATC2,NFATC1,TYK2,SOCS3,IKBKG,FYN,TAB2,TNFRSF1A,PPP3CC,TNFRSF11B,LILRA6,FOSL1,MAPK12,TRAF2,TGFBR1,TGFB2,TGFBR2,SIRPA,JUN,SQSTM1,PIK3R5,JUNB,MAPK9,NCF1,IRF9,MAPK11,MAP3K14,MAP3K7,CREB1,SYK,TNFRSF11A,FCGR2B,IFNGR2,MAP2K7,PIK3R1,FHL2,IFNAR1,LILRA4,CTSK,FOS,BLNK,FCGR3A,IL1R1,AKT3,CSF1,NFKBIA,LILRB5,FCGR2A,CSF1R
ko04380	Osteoclast differentiation	0.0115187874742473	-4.46377588322557	132	73	0.0240765171503958	3032	6715	7189,1540,2355,3937,1432,4688,353514,8651,2209,3551,5336,4286,4790,5296,2354,5290,8503,5971,9103,4791,6688,55423,4689,207,4773,4772,7297,9021,8517,2534,23118,7132,5533,4982,79168,8061,6300,7186,7046,7042,7048,140885,3725,8878,23533,3726,5601,653361,10379,5600,9020,6885,1385,6850,8792,2213,3460,5609,5295,2274,3454,23547,1513,2353,29760,2214,3554,10000,1435,4792,10990,2212,1436	TRAF6,CYLD,FOSL2,LCP2,MAPK14,NCF2,LILRA5,SOCS1,FCGR1A,IKBKB,PLCG2,MITF,NFKB1,PIK3R2,FOSB,PIK3CA,PIK3R3,RELB,FCGR2C,NFKB2,SPI1,SIRPG,NCF4,AKT1,NFATC2,NFATC1,TYK2,SOCS3,IKBKG,FYN,TAB2,TNFRSF1A,PPP3CC,TNFRSF11B,LILRA6,FOSL1,MAPK12,TRAF2,TGFBR1,TGFB2,TGFBR2,SIRPA,JUN,SQSTM1,PIK3R5,JUNB,MAPK9,NCF1,IRF9,MAPK11,MAP3K14,MAP3K7,CREB1,SYK,TNFRSF11A,FCGR2B,IFNGR2,MAP2K7,PIK3R1,FHL2,IFNAR1,LILRA4,CTSK,FOS,BLNK,FCGR3A,IL1R1,AKT3,CSF1,NFKBIA,LILRB5,FCGR2A,CSF1R
ko04020	Calcium signaling pathway	0.0128185694951429	-4.35686041755776	181	97	0.0319920844327177	3032	6715	5724,5023,2769,552,4923,5137,8912,2064,57105,5578,5566,5331,5136,5336,3362,109,7419,779,148,815,5159,5567,113,10105,1139,7125,80228,91807,492,5333,107,5257,5613,3973,7416,3710,9630,93129,3363,817,5335,291,114,4638,2185,5533,774,56848,7134,3707,89869,3358,489,2774,1128,8877,113026,136,3274,147,1816,51806,84876,57620,2065,623,5330,8911,5261,818,1131,777,773,491,2902,6262,952,154,3360,2767,1956,553,5350,6865,816,3708,163688,5332,7201,810,4843,5026,493,3269,1812,6870,5731	PTAFR,P2RX1,GNA15,AVPR1A,NTSR1,PDE1C,CACNA1H,ERBB2,CYSLTR2,PRKCA,PRKACA,PLCB3,PDE1A,PLCG2,HTR6,ADCY3,VDAC3,CACNA1S,ADRA1A,CAMK2A,PDGFRB,PRKACB,ADCY7,PPIF,CHRNA7,TNNC2,ORAI2,MYLK3,ATP2B3,PLCD1,ADCY1,PHKB,PRKX,LHCGR,VDAC1,ITPR3,GNA14,ORAI3,HTR7,CAMK2D,PLCG1,SLC25A4,ADCY8,MYLK,PTK2B,PPP3CC,CACNA1B,SPHK2,TNNC1,ITPKB,PLCZ1,HTR2C,ATP2A3,GNAL,CHRM1,SPHK1,PLCD3,ADORA2B,HRH2,ADRA1B,DRD5,CALML5,ORAI1,STIM2,ERBB3,BDKRB1,PLCB2,CACNA1I,PHKG2,CAMK2G,CHRM3,CACNA1E,CACNA1A,ATP2B2,GRIN1,RYR2,CD38,ADRB2,HTR4,GNA11,EGFR,AVPR1B,PLN,TACR2,CAMK2B,ITPR1,CALML6,PLCB4,TRHR,CALML3,NOS2,P2RX5,ATP2B4,HRH1,DRD1,TACR3,PTGER1
hsa04020	Calcium signaling pathway	0.0128185694951429	-4.35686041755776	181	97	0.0319920844327177	3032	6715	5724,5023,2769,552,4923,5137,8912,2064,57105,5578,5566,5331,5136,5336,3362,109,7419,779,148,815,5159,5567,113,10105,1139,7125,80228,91807,492,5333,107,5257,5613,3973,7416,3710,9630,93129,3363,817,5335,291,114,4638,2185,5533,774,56848,7134,3707,89869,3358,489,2774,1128,8877,113026,136,3274,147,1816,51806,84876,57620,2065,623,5330,8911,5261,818,1131,777,773,491,2902,6262,952,154,3360,2767,1956,553,5350,6865,816,3708,163688,5332,7201,810,4843,5026,493,3269,1812,6870,5731	PTAFR,P2RX1,GNA15,AVPR1A,NTSR1,PDE1C,CACNA1H,ERBB2,CYSLTR2,PRKCA,PRKACA,PLCB3,PDE1A,PLCG2,HTR6,ADCY3,VDAC3,CACNA1S,ADRA1A,CAMK2A,PDGFRB,PRKACB,ADCY7,PPIF,CHRNA7,TNNC2,ORAI2,MYLK3,ATP2B3,PLCD1,ADCY1,PHKB,PRKX,LHCGR,VDAC1,ITPR3,GNA14,ORAI3,HTR7,CAMK2D,PLCG1,SLC25A4,ADCY8,MYLK,PTK2B,PPP3CC,CACNA1B,SPHK2,TNNC1,ITPKB,PLCZ1,HTR2C,ATP2A3,GNAL,CHRM1,SPHK1,PLCD3,ADORA2B,HRH2,ADRA1B,DRD5,CALML5,ORAI1,STIM2,ERBB3,BDKRB1,PLCB2,CACNA1I,PHKG2,CAMK2G,CHRM3,CACNA1E,CACNA1A,ATP2B2,GRIN1,RYR2,CD38,ADRB2,HTR4,GNA11,EGFR,AVPR1B,PLN,TACR2,CAMK2B,ITPR1,CALML6,PLCB4,TRHR,CALML3,NOS2,P2RX5,ATP2B4,HRH1,DRD1,TACR3,PTGER1
hsa04014	Ras signaling pathway	0.0151305713043697	-4.19103799218757	227	119	0.0392480211081794	3032	6715	5321,9462,5894,10928,10156,2782,22808,5578,5566,2783,5881,25759,5154,27,56924,6464,53358,5899,3551,5336,4790,5296,5290,8503,55770,4233,3815,7074,5159,5567,27040,207,2249,2788,2257,83593,5613,5868,7422,5869,8399,2260,3630,2246,5898,3363,5228,8517,5335,8605,1969,1945,59345,2321,4254,1946,3082,5863,284,399694,5922,11186,5900,81579,5338,2113,100137049,10298,25,2261,5880,51806,23533,2324,2793,5601,5781,100271927,51764,22800,8398,9610,123745,2264,5058,56034,5923,2254,29110,6237,27006,5295,1944,8437,2902,22821,2786,3845,4804,5605,1956,2248,283748,3643,2114,255189,1435,10000,8817,26281,163688,356,51378,5337,1942,3265,810,5878,1436	PLA2G4A,RASAL2,RAF1,RALBP1,RASA4,GNB1,MRAS,PRKCA,PRKACA,GNB2,RAC3,SHC2,PDGFA,ABL2,PAK6,SHC1,SHC3,RALB,IKBKB,PLCG2,NFKB1,PIK3R2,PIK3CA,PIK3R3,EXOC2,MET,KIT,TIAM1,PDGFRB,PRKACB,LAT,AKT1,FGF4,GNG7,FGF12,RASSF5,PRKX,RAB5A,VEGFA,RAB5B,PLA2G10,FGFR1,INS,FGF1,RALA,HTR7,PGF,IKBKG,PLCG1,PLA2G4C,EPHA2,EFNA4,GNB4,FLT1,KITLG,EFNA5,HGF,RGL2,ANGPT1,SHC4,RASA2,RASSF1,RALGDS,PLA2G12A,PLD2,ETS1,PLA2G4B,PAK4,ABL1,FGFR3,RAC2,CALML5,PIK3R5,FLT4,GNGT2,MAPK9,PTPN11,RASA4B,GNG13,RRAS2,PLA2G6,RIN1,PLA2G4E,FGFR4,PAK1,PDGFC,RASGRF1,FGF9,TBK1,RRAS,FGF22,PIK3R1,EFNA3,RASAL1,GRIN1,RASA3,GNG4,KRAS,NGFR,MAP2K2,EGFR,FGF3,PLA2G4D,INSR,ETS2,PLA2G4F,CSF1,AKT3,FGF18,FGF20,CALML6,FASLG,ANGPT4,PLD1,EFNA1,HRAS,CALML3,RAB5C,CSF1R
hsa05100	Bacterial invasion of epithelial cells	0.0168288093080002	-4.08466302146994	76	44	0.0145118733509235	3032	6715	10163,391,81873,26052,399694,2335,71,1793,1495,859,6714,25759,1399,1499,6464,999,53358,23533,10092,5296,5290,1785,8503,2017,1212,4233,7414,55964,5829,10801,23157,5295,868,23176,5747,857,867,9564,10552,26084,7454,3688,1211,60	WASF2,RHOG,ARPC5L,DNM3,SHC4,FN1,ACTG1,DOCK1,CTNNA1,CAV3,SRC,SHC2,CRKL,CTNNB1,SHC1,CDH1,SHC3,PIK3R5,ARPC5,PIK3R2,PIK3CA,DNM2,PIK3R3,CTTN,CLTB,MET,VCL,SEPT3,PXN,SEPT9,SEPT6,PIK3R1,CBLB,SEPT8,PTK2,CAV1,CBL,BCAR1,ARPC1A,ARHGEF26,WAS,ITGB1,CLTA,ACTB
ko05100	Bacterial invasion of epithelial cells	0.0168288093080002	-4.08466302146994	76	44	0.0145118733509235	3032	6715	10163,391,81873,26052,399694,2335,71,1793,1495,859,6714,25759,1399,1499,6464,999,53358,23533,10092,5296,5290,1785,8503,2017,1212,4233,7414,55964,5829,10801,23157,5295,868,23176,5747,857,867,9564,10552,26084,7454,3688,1211,60	WASF2,RHOG,ARPC5L,DNM3,SHC4,FN1,ACTG1,DOCK1,CTNNA1,CAV3,SRC,SHC2,CRKL,CTNNB1,SHC1,CDH1,SHC3,PIK3R5,ARPC5,PIK3R2,PIK3CA,DNM2,PIK3R3,CTTN,CLTB,MET,VCL,SEPT3,PXN,SEPT9,SEPT6,PIK3R1,CBLB,SEPT8,PTK2,CAV1,CBL,BCAR1,ARPC1A,ARHGEF26,WAS,ITGB1,CLTA,ACTB
M00549	Nucleotide sugar biosynthesis, glucose => UDP-glucose	0.0184617999645269	-3.9920515484568	8	7	0.00230870712401055	3032	6715	5236,80201,3098,2645,7360,3101,3099	PGM1,HKDC1,HK1,GCK,UGP2,HK3,HK2
hsa_M00549	Nucleotide sugar biosynthesis, glucose => UDP-glucose	0.0184617999645269	-3.9920515484568	8	7	0.00230870712401055	3032	6715	5236,80201,3098,2645,7360,3101,3099	PGM1,HKDC1,HK1,GCK,UGP2,HK3,HK2
hsa00524	Butirosin and neomycin biosynthesis	0.0187339655922635	-3.97741706084344	5	5	0.0016490765171504	3032	6715	80201,3098,2645,3101,3099	HKDC1,HK1,GCK,HK3,HK2
ko00524	Butirosin and neomycin biosynthesis	0.0187339655922635	-3.97741706084344	5	5	0.0016490765171504	3032	6715	80201,3098,2645,3101,3099	HKDC1,HK1,GCK,HK3,HK2
hsa05203	Viral carcinogenesis	0.0199161195385879	-3.91622584808184	206	108	0.0356200527704486	3032	6715	7874,9134,64764,79885,8349,3661,1026,27044,1960,10013,7531,4067,5566,898,440689,595,6672,2968,5366,3572,4790,5296,1739,8379,5290,8503,7419,4791,1386,3017,5567,718,578,468,8370,1019,991,85236,10971,90993,5613,87,23352,983,1959,2934,8517,7185,9759,1233,5933,9093,6722,81,3665,7187,128312,7188,286436,3066,1388,8850,6908,5922,7186,1111,88,83933,8970,9586,6714,3105,9734,4055,3725,2961,7337,23533,51564,5902,896,10379,3107,1385,6774,6850,9114,2967,148327,5829,2648,8841,5295,3845,23513,5315,55697,9261,158983,2957,4792,7534,6776,3516,387332,3265,1642,1234	USP7,CCNE2,CREB3L2,HDAC11,HIST2H2BE,IRF3,CDKN1A,SND1,EGR3,HDAC6,YWHAE,LYN,PRKACA,CCNE1,HIST2H2BF,CCND1,SP100,GTF2H4,PMAIP1,IL6ST,NFKB1,PIK3R2,DLG1,MAD1L1,PIK3CA,PIK3R3,VDAC3,NFKB2,ATF2,HIST1H2BD,PRKACB,C3,BAK1,ATF4,HIST2H4A,CDK4,CDC20,HIST1H2BK,YWHAQ,CREB3L1,PRKX,ACTN1,UBR4,CDK1,EGR2,GSN,IKBKG,TRAF1,HDAC4,CCR4,RBL1,DNAJA3,SRF,ACTN4,IRF7,TRAF3,HIST3H2BB,TRAF5,H2BFM,HDAC2,ATF6B,KAT2B,TBP,RASA2,TRAF2,CHEK1,ACTN2,HDAC10,HIST1H2BJ,CREB5,SRC,HLA-A,HDAC9,LTBR,JUN,GTF2E2,UBE3A,PIK3R5,HDAC7,RANBP1,CCND3,IRF9,HLA-C,CREB1,STAT3,SYK,ATP6V0D1,GTF2H3,CREB3L4,PXN,KAT2A,HDAC3,PIK3R1,KRAS,SCRIB,PKM,VAC14,MAPKAPK2,H2BFWT,GTF2A1,NFKBIA,YWHAZ,STAT5A,RBPJ,TBPL2,HRAS,DDB1,CCR5
ko05203	Viral carcinogenesis	0.0199161195385879	-3.91622584808184	206	108	0.0356200527704486	3032	6715	7874,9134,64764,79885,8349,3661,1026,27044,1960,10013,7531,4067,5566,898,440689,595,6672,2968,5366,3572,4790,5296,1739,8379,5290,8503,7419,4791,1386,3017,5567,718,578,468,8370,1019,991,85236,10971,90993,5613,87,23352,983,1959,2934,8517,7185,9759,1233,5933,9093,6722,81,3665,7187,128312,7188,286436,3066,1388,8850,6908,5922,7186,1111,88,83933,8970,9586,6714,3105,9734,4055,3725,2961,7337,23533,51564,5902,896,10379,3107,1385,6774,6850,9114,2967,148327,5829,2648,8841,5295,3845,23513,5315,55697,9261,158983,2957,4792,7534,6776,3516,387332,3265,1642,1234	USP7,CCNE2,CREB3L2,HDAC11,HIST2H2BE,IRF3,CDKN1A,SND1,EGR3,HDAC6,YWHAE,LYN,PRKACA,CCNE1,HIST2H2BF,CCND1,SP100,GTF2H4,PMAIP1,IL6ST,NFKB1,PIK3R2,DLG1,MAD1L1,PIK3CA,PIK3R3,VDAC3,NFKB2,ATF2,HIST1H2BD,PRKACB,C3,BAK1,ATF4,HIST2H4A,CDK4,CDC20,HIST1H2BK,YWHAQ,CREB3L1,PRKX,ACTN1,UBR4,CDK1,EGR2,GSN,IKBKG,TRAF1,HDAC4,CCR4,RBL1,DNAJA3,SRF,ACTN4,IRF7,TRAF3,HIST3H2BB,TRAF5,H2BFM,HDAC2,ATF6B,KAT2B,TBP,RASA2,TRAF2,CHEK1,ACTN2,HDAC10,HIST1H2BJ,CREB5,SRC,HLA-A,HDAC9,LTBR,JUN,GTF2E2,UBE3A,PIK3R5,HDAC7,RANBP1,CCND3,IRF9,HLA-C,CREB1,STAT3,SYK,ATP6V0D1,GTF2H3,CREB3L4,PXN,KAT2A,HDAC3,PIK3R1,KRAS,SCRIB,PKM,VAC14,MAPKAPK2,H2BFWT,GTF2A1,NFKBIA,YWHAZ,STAT5A,RBPJ,TBPL2,HRAS,DDB1,CCR5
ko05216	Thyroid cancer	0.021654778871462	-3.83252911579867	29	19	0.0062664907651715	3032	6715	6258,7170,4914,6256,5979,3845,6932,5605,6934,595,7175,83439,999,1499,7849,8030,4609,10342,3265	RXRG,TPM3,NTRK1,RXRA,RET,KRAS,TCF7,MAP2K2,TCF7L2,CCND1,TPR,TCF7L1,CDH1,CTNNB1,PAX8,CCDC6,MYC,TFG,HRAS
hsa05216	Thyroid cancer	0.021654778871462	-3.83252911579867	29	19	0.0062664907651715	3032	6715	6258,7170,4914,6256,5979,3845,6932,5605,6934,595,7175,83439,999,1499,7849,8030,4609,10342,3265	RXRG,TPM3,NTRK1,RXRA,RET,KRAS,TCF7,MAP2K2,TCF7L2,CCND1,TPR,TCF7L1,CDH1,CTNNB1,PAX8,CCDC6,MYC,TFG,HRAS
hsa05220	Chronic myeloid leukemia	0.021970988398064	-3.81803240506485	73	42	0.0138522427440633	3032	6715	399694,5894,7046,1488,1026,7042,7048,25759,2122,25,1399,595,6464,53358,23533,4609,3551,4790,5296,5781,5290,8503,613,207,1019,5295,1871,868,3845,867,5605,4088,8517,10000,4792,6776,861,1870,3265,4089,1487,3066	SHC4,RAF1,TGFBR1,CTBP2,CDKN1A,TGFB2,TGFBR2,SHC2,MECOM,ABL1,CRKL,CCND1,SHC1,SHC3,PIK3R5,MYC,IKBKB,NFKB1,PIK3R2,PTPN11,PIK3CA,PIK3R3,BCR,AKT1,CDK4,PIK3R1,E2F3,CBLB,KRAS,CBL,MAP2K2,SMAD3,IKBKG,AKT3,NFKBIA,STAT5A,RUNX1,E2F2,HRAS,SMAD4,CTBP1,HDAC2
ko05220	Chronic myeloid leukemia	0.021970988398064	-3.81803240506485	73	42	0.0138522427440633	3032	6715	399694,5894,7046,1488,1026,7042,7048,25759,2122,25,1399,595,6464,53358,23533,4609,3551,4790,5296,5781,5290,8503,613,207,1019,5295,1871,868,3845,867,5605,4088,8517,10000,4792,6776,861,1870,3265,4089,1487,3066	SHC4,RAF1,TGFBR1,CTBP2,CDKN1A,TGFB2,TGFBR2,SHC2,MECOM,ABL1,CRKL,CCND1,SHC1,SHC3,PIK3R5,MYC,IKBKB,NFKB1,PIK3R2,PTPN11,PIK3CA,PIK3R3,BCR,AKT1,CDK4,PIK3R1,E2F3,CBLB,KRAS,CBL,MAP2K2,SMAD3,IKBKG,AKT3,NFKBIA,STAT5A,RUNX1,E2F2,HRAS,SMAD4,CTBP1,HDAC2
ko00532	Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate	0.0219780424168105	-3.81771139599246	20	14	0.00461741424802111	3032	6715	126792,337876,10090,50515,51363,55790,26229,9469,113189,22856,166012,11285,55454,79586	B3GALT6,CHSY3,UST,CHST11,CHST15,CSGALNACT1,B3GAT3,CHST3,CHST14,CHSY1,CHST13,B4GALT7,CSGALNACT2,CHPF
hsa00532	Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate	0.0219780424168105	-3.81771139599246	20	14	0.00461741424802111	3032	6715	126792,337876,10090,50515,51363,55790,26229,9469,113189,22856,166012,55454,11285,79586	B3GALT6,CHSY3,UST,CHST11,CHST15,CSGALNACT1,B3GAT3,CHST3,CHST14,CHSY1,CHST13,CSGALNACT2,B4GALT7,CHPF
ko05110	Vibrio cholerae infection	0.0255730998747213	-3.66621426610313	54	32	0.0105540897097625	3032	6715	71,23480,537,90423,7082,375,5578,5566,525,9601,9414,533,5336,109,51606,6558,9114,5567,55176,9550,5613,4583,3784,11014,5335,29927,10312,127124,527,60,528,8992	ACTG1,SEC61G,ATP6AP1,ATP6V1E2,TJP1,ARF1,PRKCA,PRKACA,ATP6V1B1,PDIA4,TJP2,ATP6V0B,PLCG2,ADCY3,ATP6V1H,SLC12A2,ATP6V0D1,PRKACB,SEC61A2,ATP6V1G1,PRKX,MUC2,KCNQ1,KDELR2,PLCG1,SEC61A1,TCIRG1,ATP6V1G3,ATP6V0C,ACTB,ATP6V1C1,ATP6V0E1
hsa05110	Vibrio cholerae infection	0.0255730998747213	-3.66621426610313	54	32	0.0105540897097625	3032	6715	71,23480,537,90423,7082,375,5578,5566,525,9601,9414,533,5336,109,51606,6558,9114,5567,55176,9550,5613,4583,3784,11014,5335,29927,10312,127124,527,60,528,8992	ACTG1,SEC61G,ATP6AP1,ATP6V1E2,TJP1,ARF1,PRKCA,PRKACA,ATP6V1B1,PDIA4,TJP2,ATP6V0B,PLCG2,ADCY3,ATP6V1H,SLC12A2,ATP6V0D1,PRKACB,SEC61A2,ATP6V1G1,PRKX,MUC2,KCNQ1,KDELR2,PLCG1,SEC61A1,TCIRG1,ATP6V1G3,ATP6V0C,ACTB,ATP6V1C1,ATP6V0E1
M00413	FA core complex	0.0279280799968403	-3.5781226447879	10	8	0.00263852242744063	3032	6715	2187,2176,91442,80233,2189,2175,2178,2188	FANCB,FANCC,C19orf40,C17orf70,FANCG,FANCA,FANCE,FANCF
hsa_M00413	FA core complex	0.0279280799968403	-3.5781226447879	10	8	0.00263852242744063	3032	6715	2187,2176,91442,80233,2189,2175,2178,2188	FANCB,FANCC,C19orf40,C17orf70,FANCG,FANCA,FANCE,FANCF
hsa04110	Cell cycle	0.0280503449778623	-3.57375434841304	124	67	0.0220976253298153	3032	6715	9134,1026,7531,891,898,4173,595,64682,7465,5111,51343,10393,8379,51434,994,1032,7709,902,9978,1019,991,1871,10971,990,701,9088,4171,8697,995,983,4088,4087,8881,5933,4616,8243,2932,6500,7029,1870,4089,3066,4172,51433,1028,10926,1111,7042,25,4174,4609,896,545,699,993,4999,10274,9184,5591,1647,996,7027,472,7534,29945,2810,5885	CCNE2,CDKN1A,YWHAE,CCNB1,CCNE1,MCM4,CCND1,ANAPC1,WEE1,PCNA,FZR1,ANAPC10,MAD1L1,ANAPC7,CDC25B,CDKN2D,ZBTB17,CCNH,RBX1,CDK4,CDC20,E2F3,YWHAQ,CDC6,BUB1B,PKMYT1,MCM2,CDC23,CDC25C,CDK1,SMAD3,SMAD2,CDC16,RBL1,GADD45B,SMC1A,GSK3B,SKP1,TFDP2,E2F2,SMAD4,HDAC2,MCM3,ANAPC5,CDKN1C,DBF4,CHEK1,TGFB2,ABL1,MCM5,MYC,CCND3,ATR,BUB1,CDC25A,ORC2,STAG1,BUB3,PRKDC,GADD45A,CDC27,TFDP1,ATM,YWHAZ,ANAPC4,SFN,RAD21
ko04110	Cell cycle	0.0280503449778623	-3.57375434841304	124	67	0.0220976253298153	3032	6715	9134,1026,7531,891,898,4173,595,64682,7465,5111,51343,10393,8379,51434,994,1032,7709,902,9978,1019,991,1871,10971,990,701,9088,4171,8697,995,983,4088,4087,8881,5933,4616,8243,2932,6500,7029,1870,4089,3066,4172,51433,1028,10926,1111,7042,25,4174,4609,896,545,699,993,4999,10274,9184,5591,1647,996,7027,472,7534,29945,2810,5885	CCNE2,CDKN1A,YWHAE,CCNB1,CCNE1,MCM4,CCND1,ANAPC1,WEE1,PCNA,FZR1,ANAPC10,MAD1L1,ANAPC7,CDC25B,CDKN2D,ZBTB17,CCNH,RBX1,CDK4,CDC20,E2F3,YWHAQ,CDC6,BUB1B,PKMYT1,MCM2,CDC23,CDC25C,CDK1,SMAD3,SMAD2,CDC16,RBL1,GADD45B,SMC1A,GSK3B,SKP1,TFDP2,E2F2,SMAD4,HDAC2,MCM3,ANAPC5,CDKN1C,DBF4,CHEK1,TGFB2,ABL1,MCM5,MYC,CCND3,ATR,BUB1,CDC25A,ORC2,STAG1,BUB3,PRKDC,GADD45A,CDC27,TFDP1,ATM,YWHAZ,ANAPC4,SFN,RAD21
ko04960	Aldosterone-regulated sodium reabsorption	0.028855303259601	-3.54546148109793	39	24	0.0079155672823219	3032	6715	5170,5295,480,3845,53828,481,5578,9351,3630,476,3643,6337,486,23533,3291,5296,5290,6446,8503,6338,477,4306,2810,478	PDPK1,PIK3R1,ATP1A4,KRAS,FXYD4,ATP1B1,PRKCA,SLC9A3R2,INS,ATP1A1,INSR,SCNN1A,FXYD2,PIK3R5,HSD11B2,PIK3R2,PIK3CA,SGK1,PIK3R3,SCNN1B,ATP1A2,NR3C2,SFN,ATP1A3
hsa04960	Aldosterone-regulated sodium reabsorption	0.028855303259601	-3.54546148109793	39	24	0.0079155672823219	3032	6715	5170,5295,480,3845,53828,481,5578,9351,3630,476,3643,6337,486,23533,3291,5296,5290,6446,8503,6338,477,4306,2810,478	PDPK1,PIK3R1,ATP1A4,KRAS,FXYD4,ATP1B1,PRKCA,SLC9A3R2,INS,ATP1A1,INSR,SCNN1A,FXYD2,PIK3R5,HSD11B2,PIK3R2,PIK3CA,SGK1,PIK3R3,SCNN1B,ATP1A2,NR3C2,SFN,ATP1A3
M00089	Triacylglycerol biosynthesis	0.030817159608886	-3.47968361398336	17	12	0.00395778364116095	3032	6715	8611,10555,346606,150763,56895,8612,84649,154141,56894,57678,8694,129642	PPAP2A,AGPAT2,MOGAT3,GPAT2,AGPAT4,PPAP2C,DGAT2,MBOAT1,AGPAT3,GPAM,DGAT1,MBOAT2
hsa_M00089	Triacylglycerol biosynthesis	0.030817159608886	-3.47968361398336	17	12	0.00395778364116095	3032	6715	8611,10555,346606,150763,56895,8612,84649,154141,56894,57678,8694,129642	PPAP2A,AGPAT2,MOGAT3,GPAT2,AGPAT4,PPAP2C,DGAT2,MBOAT1,AGPAT3,GPAM,DGAT1,MBOAT2
ko05169	Epstein-Barr virus infection	0.0332173174011781	-3.40468393058089	203	105	0.0346306068601583	3032	6715	7874,7189,9451,8737,377841,3661,1026,27044,7531,4067,1432,5566,3303,51728,5606,3113,3551,5336,4790,5296,5701,10213,5290,8503,5971,4791,1386,6688,3588,3306,5567,207,26993,5441,3312,10971,1380,5613,7431,3586,8021,983,7297,3310,8517,5335,7514,7185,9759,23118,5709,5714,5757,55718,2932,7187,5437,3315,7188,3066,6300,548644,9612,4794,5440,6908,7186,3383,3105,965,3123,3725,661,2961,3654,23533,4609,5601,5600,3107,960,9020,6885,6774,6850,29110,5438,7128,5609,5295,84265,27102,952,5710,3304,5704,2268,5439,10000,4792,5434,7534,3516,387332,246721	USP7,TRAF6,EIF2AK3,RIPK1,ENTPD8,IRF3,CDKN1A,SND1,YWHAE,LYN,MAPK14,PRKACA,HSPA1A,POLR3K,MAP2K3,HLA-DPA1,IKBKB,PLCG2,NFKB1,PIK3R2,PSMC2,PSMD14,PIK3CA,PIK3R3,RELB,NFKB2,ATF2,SPI1,IL10RB,HSPA2,PRKACB,AKT1,AKAP8L,POLR2L,HSPA8,YWHAQ,CR2,PRKX,VIM,IL10,NUP214,CDK1,TYK2,HSPA6,IKBKG,PLCG1,XPO1,TRAF1,HDAC4,TAB2,PSMD3,PSMD8,PTMA,POLR3E,GSK3B,TRAF3,POLR2H,HSPB1,TRAF5,HDAC2,MAPK12,POLR2J3,NCOR2,NFKBIE,POLR2K,TBP,TRAF2,ICAM1,HLA-A,CD58,HLA-DRB1,JUN,POLR3D,GTF2E2,IRAK1,PIK3R5,MYC,MAPK9,MAPK11,HLA-C,CD44,MAP3K14,MAP3K7,STAT3,SYK,TBK1,POLR2I,TNFAIP3,MAP2K7,PIK3R1,POLR3GL,EIF2AK1,CD38,PSMD4,HSPA1B,PSMC4,FGR,POLR2J,AKT3,NFKBIA,POLR2E,YWHAZ,RBPJ,TBPL2,POLR2J2
hsa05169	Epstein-Barr virus infection	0.0332173174011781	-3.40468393058089	203	105	0.0346306068601583	3032	6715	7874,7189,9451,8737,377841,3661,1026,27044,7531,4067,1432,5566,3303,51728,5606,3113,3551,5336,4790,5296,5701,10213,5290,8503,5971,4791,1386,6688,3588,3306,5567,207,26993,5441,3312,10971,1380,5613,7431,3586,8021,983,7297,3310,8517,5335,7514,7185,9759,23118,5709,5714,5757,55718,2932,7187,5437,3315,7188,3066,6300,548644,9612,4794,5440,6908,7186,3383,3105,965,3123,3725,661,2961,3654,23533,4609,5601,5600,3107,960,9020,6885,6774,6850,29110,5438,7128,5609,5295,84265,27102,952,5710,3304,5704,2268,5439,10000,4792,5434,7534,3516,387332,246721	USP7,TRAF6,EIF2AK3,RIPK1,ENTPD8,IRF3,CDKN1A,SND1,YWHAE,LYN,MAPK14,PRKACA,HSPA1A,POLR3K,MAP2K3,HLA-DPA1,IKBKB,PLCG2,NFKB1,PIK3R2,PSMC2,PSMD14,PIK3CA,PIK3R3,RELB,NFKB2,ATF2,SPI1,IL10RB,HSPA2,PRKACB,AKT1,AKAP8L,POLR2L,HSPA8,YWHAQ,CR2,PRKX,VIM,IL10,NUP214,CDK1,TYK2,HSPA6,IKBKG,PLCG1,XPO1,TRAF1,HDAC4,TAB2,PSMD3,PSMD8,PTMA,POLR3E,GSK3B,TRAF3,POLR2H,HSPB1,TRAF5,HDAC2,MAPK12,POLR2J3,NCOR2,NFKBIE,POLR2K,TBP,TRAF2,ICAM1,HLA-A,CD58,HLA-DRB1,JUN,POLR3D,GTF2E2,IRAK1,PIK3R5,MYC,MAPK9,MAPK11,HLA-C,CD44,MAP3K14,MAP3K7,STAT3,SYK,TBK1,POLR2I,TNFAIP3,MAP2K7,PIK3R1,POLR3GL,EIF2AK1,CD38,PSMD4,HSPA1B,PSMC4,FGR,POLR2J,AKT3,NFKBIA,POLR2E,YWHAZ,RBPJ,TBPL2,POLR2J2
ko04728	Dopaminergic synapse	0.0335287802133166	-3.39535109813034	131	70	0.0230870712401055	3032	6715	64764,3763,2782,5578,1432,5566,2783,5331,5518,1312,5499,5521,1386,815,5567,468,207,2931,6531,2788,90993,5613,3710,5515,3762,5529,817,3765,5525,59345,406,4128,2932,5533,5522,774,55844,5528,6300,1388,2774,3800,9586,1815,2890,1816,51806,2793,5601,5600,51764,1385,2771,5330,818,1644,148327,28227,773,2786,2353,111,10000,816,3708,163688,5332,6571,810,1812	CREB3L2,KCNJ6,GNB1,PRKCA,MAPK14,PRKACA,GNB2,PLCB3,PPP2R1A,COMT,PPP1CA,PPP2R2B,ATF2,CAMK2A,PRKACB,ATF4,AKT1,GSK3A,SLC6A3,GNG7,CREB3L1,PRKX,ITPR3,PPP2CA,KCNJ5,PPP2R5E,CAMK2D,KCNJ9,PPP2R5A,GNB4,ARNTL,MAOA,GSK3B,PPP3CC,PPP2R2C,CACNA1B,PPP2R2D,PPP2R5D,MAPK12,ATF6B,GNAL,KIF5C,CREB5,DRD4,GRIA1,DRD5,CALML5,GNGT2,MAPK9,MAPK11,GNG13,CREB1,GNAI2,PLCB2,CAMK2G,DDC,CREB3L4,PPP2R3B,CACNA1A,GNG4,FOS,ADCY5,AKT3,CAMK2B,ITPR1,CALML6,PLCB4,SLC18A2,CALML3,DRD1
hsa04728	Dopaminergic synapse	0.0335287802133166	-3.39535109813034	131	70	0.0230870712401055	3032	6715	64764,3763,2782,5578,1432,5566,2783,5331,5518,1312,5499,5521,1386,815,5567,468,207,2931,6531,2788,90993,5613,3710,5515,3762,5529,817,3765,5525,59345,406,4128,2932,5533,5522,774,55844,5528,6300,1388,2774,3800,9586,1815,2890,1816,51806,2793,5601,5600,51764,1385,2771,5330,818,1644,148327,28227,773,2786,2353,111,10000,816,3708,163688,5332,6571,810,1812	CREB3L2,KCNJ6,GNB1,PRKCA,MAPK14,PRKACA,GNB2,PLCB3,PPP2R1A,COMT,PPP1CA,PPP2R2B,ATF2,CAMK2A,PRKACB,ATF4,AKT1,GSK3A,SLC6A3,GNG7,CREB3L1,PRKX,ITPR3,PPP2CA,KCNJ5,PPP2R5E,CAMK2D,KCNJ9,PPP2R5A,GNB4,ARNTL,MAOA,GSK3B,PPP3CC,PPP2R2C,CACNA1B,PPP2R2D,PPP2R5D,MAPK12,ATF6B,GNAL,KIF5C,CREB5,DRD4,GRIA1,DRD5,CALML5,GNGT2,MAPK9,MAPK11,GNG13,CREB1,GNAI2,PLCB2,CAMK2G,DDC,CREB3L4,PPP2R3B,CACNA1A,GNG4,FOS,ADCY5,AKT3,CAMK2B,ITPR1,CALML6,PLCB4,SLC18A2,CALML3,DRD1
hsa04913	Ovarian steroidogenesis	0.0340420251998831	-3.38015948233804	51	30	0.00989445910290238	3032	6715	3292,5321,1588,3949,107,3294,5613,51478,3973,2492,5566,100137049,3630,240,283748,5743,3643,8605,1583,255189,111,114,3972,112,109,949,5567,123745,2661,113	HSD17B1,PLA2G4A,CYP19A1,LDLR,ADCY1,HSD17B2,PRKX,HSD17B7,LHCGR,FSHR,PRKACA,PLA2G4B,INS,ALOX5,PLA2G4D,PTGS2,INSR,PLA2G4C,CYP11A1,PLA2G4F,ADCY5,ADCY8,LHB,ADCY6,ADCY3,SCARB1,PRKACB,PLA2G4E,GDF9,ADCY7
ko04913	Ovarian steroidogenesis	0.0340420251998831	-3.38015948233804	51	30	0.00989445910290238	3032	6715	3292,5321,1588,3949,107,3294,5613,51478,3973,2492,5566,100137049,3630,240,283748,5743,3643,8605,1583,255189,111,114,3972,112,109,949,5567,123745,2661,113	HSD17B1,PLA2G4A,CYP19A1,LDLR,ADCY1,HSD17B2,PRKX,HSD17B7,LHCGR,FSHR,PRKACA,PLA2G4B,INS,ALOX5,PLA2G4D,PTGS2,INSR,PLA2G4C,CYP11A1,PLA2G4F,ADCY5,ADCY8,LHB,ADCY6,ADCY3,SCARB1,PRKACB,PLA2G4E,GDF9,ADCY7
M00094	Ceramide biosynthesis	0.0363009203867264	-3.31591218302653	12	9	0.00296833773087071	3032	6715	2531,204219,8560,91012,123099,79603,10715,9517,29956	KDSR,CERS3,DEGS1,CERS5,DEGS2,CERS4,CERS1,SPTLC2,CERS2
hsa_M00094	Ceramide biosynthesis	0.0363009203867264	-3.31591218302653	12	9	0.00296833773087071	3032	6715	2531,204219,8560,91012,123099,79603,10715,9517,29956	KDSR,CERS3,DEGS1,CERS5,DEGS2,CERS4,CERS1,SPTLC2,CERS2
hsa04971	Gastric acid secretion	0.0377117568034188	-3.27778338159419	75	42	0.0138522427440633	3032	6715	2520,6522,495,5578,3766,5566,3274,5331,51806,112,6548,109,3776,5330,2771,477,496,818,815,5567,1131,113,91807,3759,480,107,5613,481,3784,3710,817,476,111,114,816,3708,4638,163688,5332,60,810,478	GAST,SLC4A2,ATP4A,PRKCA,KCNJ10,PRKACA,HRH2,PLCB3,CALML5,ADCY6,SLC9A1,ADCY3,KCNK2,PLCB2,GNAI2,ATP1A2,ATP4B,CAMK2G,CAMK2A,PRKACB,CHRM3,ADCY7,MYLK3,KCNJ2,ATP1A4,ADCY1,PRKX,ATP1B1,KCNQ1,ITPR3,CAMK2D,ATP1A1,ADCY5,ADCY8,CAMK2B,ITPR1,MYLK,CALML6,PLCB4,ACTB,CALML3,ATP1A3
ko04971	Gastric acid secretion	0.0377117568034188	-3.27778338159419	75	42	0.0138522427440633	3032	6715	2520,6522,495,5578,3766,5566,3274,5331,51806,112,6548,109,3776,5330,2771,477,496,818,815,5567,1131,113,91807,3759,480,107,5613,481,3784,3710,817,476,111,114,816,3708,4638,163688,5332,60,810,478	GAST,SLC4A2,ATP4A,PRKCA,KCNJ10,PRKACA,HRH2,PLCB3,CALML5,ADCY6,SLC9A1,ADCY3,KCNK2,PLCB2,GNAI2,ATP1A2,ATP4B,CAMK2G,CAMK2A,PRKACB,CHRM3,ADCY7,MYLK3,KCNJ2,ATP1A4,ADCY1,PRKX,ATP1B1,KCNQ1,ITPR3,CAMK2D,ATP1A1,ADCY5,ADCY8,CAMK2B,ITPR1,MYLK,CALML6,PLCB4,ACTB,CALML3,ATP1A3
ko05219	Bladder cancer	0.0406380887560092	-3.2030495054593	38	23	0.00758575197889182	3032	6715	4318,1019,5894,1871,11186,2064,3845,1026,7422,9252,5605,1613,1956,23604,595,2261,1890,999,4609,4313,3576,1870,3265	MMP9,CDK4,RAF1,E2F3,RASSF1,ERBB2,KRAS,CDKN1A,VEGFA,RPS6KA5,MAP2K2,DAPK3,EGFR,DAPK2,CCND1,FGFR3,TYMP,CDH1,MYC,MMP2,IL8,E2F2,HRAS
hsa05219	Bladder cancer	0.0406380887560092	-3.2030495054593	38	23	0.00758575197889182	3032	6715	4318,1019,5894,1871,11186,2064,3845,1026,7422,9252,5605,1613,1956,23604,595,2261,1890,999,4609,4313,3576,1870,3265	MMP9,CDK4,RAF1,E2F3,RASSF1,ERBB2,KRAS,CDKN1A,VEGFA,RPS6KA5,MAP2K2,DAPK3,EGFR,DAPK2,CCND1,FGFR3,TYMP,CDH1,MYC,MMP2,IL8,E2F2,HRAS
hsa_M00286	GINS complex	0.0415203576913656	-3.18157142524433	4	4	0.00131926121372032	3032	6715	9837,64785,51659,84296	GINS1,GINS3,GINS2,GINS4
M00286	GINS complex	0.0415203576913656	-3.18157142524433	4	4	0.00131926121372032	3032	6715	9837,64785,51659,84296	GINS1,GINS3,GINS2,GINS4
ko04722	Neurotrophin signaling pathway	0.0426114688398632	-3.15563184034741	120	64	0.0211081794195251	3032	6715	398,7189,5607,5894,6195,7531,1432,25759,1399,7161,6196,6464,53358,3551,5336,4790,5296,5664,5290,8503,815,4215,468,207,4914,4909,5335,817,396,2932,6300,399694,4794,9252,3725,10019,25,3654,51806,23533,5601,11108,5580,5781,5600,818,5170,2889,5609,5295,3845,4804,5605,9261,10603,10000,816,4792,163688,356,4217,4915,810,3265	ARHGDIG,TRAF6,MAP2K5,RAF1,RPS6KA1,YWHAE,MAPK14,SHC2,CRKL,TP73,RPS6KA2,SHC1,SHC3,IKBKB,PLCG2,NFKB1,PIK3R2,PSEN2,PIK3CA,PIK3R3,CAMK2A,MAP3K3,ATF4,AKT1,NTRK1,NTF4,PLCG1,CAMK2D,ARHGDIA,GSK3B,MAPK12,SHC4,NFKBIE,RPS6KA5,JUN,SH2B3,ABL1,IRAK1,CALML5,PIK3R5,MAPK9,PRDM4,PRKCD,PTPN11,MAPK11,CAMK2G,PDPK1,RAPGEF1,MAP2K7,PIK3R1,KRAS,NGFR,MAP2K2,MAPKAPK2,SH2B2,AKT3,CAMK2B,NFKBIA,CALML6,FASLG,MAP3K5,NTRK2,CALML3,HRAS
hsa04722	Neurotrophin signaling pathway	0.0426114688398632	-3.15563184034741	120	64	0.0211081794195251	3032	6715	398,7189,5607,5894,6195,7531,1432,25759,1399,7161,6196,6464,53358,3551,5336,4790,5296,5664,5290,8503,815,4215,468,207,4914,4909,5335,817,396,2932,6300,399694,4794,9252,3725,10019,25,3654,51806,23533,5601,11108,5580,5781,5600,818,5170,2889,5609,5295,3845,4804,5605,9261,10603,10000,816,4792,163688,356,4217,4915,810,3265	ARHGDIG,TRAF6,MAP2K5,RAF1,RPS6KA1,YWHAE,MAPK14,SHC2,CRKL,TP73,RPS6KA2,SHC1,SHC3,IKBKB,PLCG2,NFKB1,PIK3R2,PSEN2,PIK3CA,PIK3R3,CAMK2A,MAP3K3,ATF4,AKT1,NTRK1,NTF4,PLCG1,CAMK2D,ARHGDIA,GSK3B,MAPK12,SHC4,NFKBIE,RPS6KA5,JUN,SH2B3,ABL1,IRAK1,CALML5,PIK3R5,MAPK9,PRDM4,PRKCD,PTPN11,MAPK11,CAMK2G,PDPK1,RAPGEF1,MAP2K7,PIK3R1,KRAS,NGFR,MAP2K2,MAPKAPK2,SH2B2,AKT3,CAMK2B,NFKBIA,CALML6,FASLG,MAP3K5,NTRK2,CALML3,HRAS
M00389	APC/C complex	0.0435237207898873	-3.13444918399787	14	10	0.00329815303430079	3032	6715	64682,51433,8881,996,991,51343,10393,51434,8697,29945	ANAPC1,ANAPC5,CDC16,CDC27,CDC20,FZR1,ANAPC10,ANAPC7,CDC23,ANAPC4
hsa_M00389	APC/C complex	0.0435237207898873	-3.13444918399787	14	10	0.00329815303430079	3032	6715	64682,51433,8881,996,991,51343,10393,51434,8697,29945	ANAPC1,ANAPC5,CDC16,CDC27,CDC20,FZR1,ANAPC10,ANAPC7,CDC23,ANAPC4
hsa05142	Chagas disease (American trypanosomiasis)	0.0452419292757616	-3.09573098329068	104	56	0.0184696569920844	3032	6715	7189,2769,1636,2774,7046,7042,1432,7048,5331,8837,713,3725,811,3654,5518,23533,919,3551,714,4790,5296,5601,5290,8503,5600,54106,5521,5330,2771,718,207,3460,5295,107,3586,2353,2767,9630,8772,355,4088,5515,8517,4087,712,10000,4792,3576,7132,356,5332,5054,5522,55844,4843,6300	TRAF6,GNA15,ACE,GNAL,TGFBR1,TGFB2,MAPK14,TGFBR2,PLCB3,CFLAR,C1QB,JUN,CALR,IRAK1,PPP2R1A,PIK3R5,CD247,IKBKB,C1QC,NFKB1,PIK3R2,MAPK9,PIK3CA,PIK3R3,MAPK11,TLR9,PPP2R2B,PLCB2,GNAI2,C3,AKT1,IFNGR2,PIK3R1,ADCY1,IL10,FOS,GNA11,GNA14,FADD,FAS,SMAD3,PPP2CA,IKBKG,SMAD2,C1QA,AKT3,NFKBIA,IL8,TNFRSF1A,FASLG,PLCB4,SERPINE1,PPP2R2C,PPP2R2D,NOS2,MAPK12
ko05142	Chagas disease (American trypanosomiasis)	0.0452419292757616	-3.09573098329068	104	56	0.0184696569920844	3032	6715	7189,2769,1636,2774,7046,7042,1432,7048,5331,8837,713,3725,811,3654,5518,23533,919,3551,714,4790,5296,5601,5290,8503,5600,54106,5521,5330,2771,718,207,3460,5295,107,3586,2353,2767,9630,8772,355,4088,5515,8517,4087,712,10000,4792,3576,7132,356,5332,5054,5522,55844,4843,6300	TRAF6,GNA15,ACE,GNAL,TGFBR1,TGFB2,MAPK14,TGFBR2,PLCB3,CFLAR,C1QB,JUN,CALR,IRAK1,PPP2R1A,PIK3R5,CD247,IKBKB,C1QC,NFKB1,PIK3R2,MAPK9,PIK3CA,PIK3R3,MAPK11,TLR9,PPP2R2B,PLCB2,GNAI2,C3,AKT1,IFNGR2,PIK3R1,ADCY1,IL10,FOS,GNA11,GNA14,FADD,FAS,SMAD3,PPP2CA,IKBKG,SMAD2,C1QA,AKT3,NFKBIA,IL8,TNFRSF1A,FASLG,PLCB4,SERPINE1,PPP2R2C,PPP2R2D,NOS2,MAPK12
ko04330	Notch signaling pathway	0.0452470076198209	-3.09561874097159	48	28	0.00923482849604222	3032	6715	3280,4851,9612,6868,54567,2648,8850,51107,3955,4242,1488,3714,4853,9253,182,28514,5986,1840,5664,388585,113878,3516,1855,9794,1487,1856,3066,8650	HES1,NOTCH1,NCOR2,ADAM17,DLL4,KAT2A,KAT2B,APH1A,LFNG,MFNG,CTBP2,JAG2,NOTCH2,NUMBL,JAG1,DLL1,RFNG,DTX1,PSEN2,HES5,DTX2,RBPJ,DVL1,MAML1,CTBP1,DVL2,HDAC2,NUMB
hsa04330	Notch signaling pathway	0.0452470076198209	-3.09561874097159	48	28	0.00923482849604222	3032	6715	3280,4851,9612,6868,54567,2648,8850,51107,3955,4242,1488,3714,4853,9253,182,28514,5986,1840,5664,388585,113878,3516,1855,9794,1487,1856,3066,8650	HES1,NOTCH1,NCOR2,ADAM17,DLL4,KAT2A,KAT2B,APH1A,LFNG,MFNG,CTBP2,JAG2,NOTCH2,NUMBL,JAG1,DLL1,RFNG,DTX1,PSEN2,HES5,DTX2,RBPJ,DVL1,MAML1,CTBP1,DVL2,HDAC2,NUMB
hsa05030	Cocaine addiction	0.0458579745204912	-3.08220616911102	50	29	0.0095646437994723	3032	6715	64764,148327,468,1388,6531,26086,2902,90993,5613,9586,2913,5566,8851,1020,3725,8787,111,2354,4790,4128,1385,6571,2771,1386,116444,1644,5567,1812,2912	CREB3L2,CREB3L4,ATF4,ATF6B,SLC6A3,GPSM1,GRIN1,CREB3L1,PRKX,CREB5,GRM3,PRKACA,CDK5R1,CDK5,JUN,RGS9,ADCY5,FOSB,NFKB1,MAOA,CREB1,SLC18A2,GNAI2,ATF2,GRIN3B,DDC,PRKACB,DRD1,GRM2
ko05030	Cocaine addiction	0.0458579745204912	-3.08220616911102	50	29	0.0095646437994723	3032	6715	64764,148327,468,1388,6531,26086,2902,90993,5613,9586,2913,5566,8851,1020,3725,8787,111,2354,4790,4128,1385,6571,2771,1386,116444,1644,5567,1812,2912	CREB3L2,CREB3L4,ATF4,ATF6B,SLC6A3,GPSM1,GRIN1,CREB3L1,PRKX,CREB5,GRM3,PRKACA,CDK5R1,CDK5,JUN,RGS9,ADCY5,FOSB,NFKB1,MAOA,CREB1,SLC18A2,GNAI2,ATF2,GRIN3B,DDC,PRKACB,DRD1,GRM2
ko00330	Arginine and proline metabolism	0.0475349176011029	-3.046290730609	58	33	0.0108839050131926	3032	6715	384,6723,2593,435,445,4942,2752,8659,1159,95,65263,548596,54498,501,2805,1610,29920,1152,224,113451,5625,51056,2747,262,6303,57571,84735,219,4953,8974,4128,55748,4843	ARG2,SRM,GAMT,ASL,ASS1,OAT,GLUL,ALDH4A1,CKMT1B,ACY1,PYCRL,CKMT1A,SMOX,ALDH7A1,GOT1,DAO,PYCR2,CKB,ALDH3A2,ADC,PRODH,LAP3,GLUD2,AMD1,SAT1,CARNS1,CNDP1,ALDH1B1,ODC1,P4HA2,MAOA,CNDP2,NOS2
hsa00330	Arginine and proline metabolism	0.0475349176011029	-3.046290730609	58	33	0.0108839050131926	3032	6715	384,6723,2593,435,445,4942,2752,8659,1159,95,548596,54498,65263,501,2805,1610,29920,1152,224,113451,5625,51056,2747,6303,262,57571,84735,219,4953,8974,4128,55748,4843	ARG2,SRM,GAMT,ASL,ASS1,OAT,GLUL,ALDH4A1,CKMT1B,ACY1,CKMT1A,SMOX,PYCRL,ALDH7A1,GOT1,DAO,PYCR2,CKB,ALDH3A2,ADC,PRODH,LAP3,GLUD2,SAT1,AMD1,CARNS1,CNDP1,ALDH1B1,ODC1,P4HA2,MAOA,CNDP2,NOS2
hsa04914	Progesterone-mediated oocyte maturation	0.0475448618105576	-3.04608155449285	86	47	0.0155013192612137	3032	6715	51433,5894,6195,891,1432,5566,5139,64682,6196,23533,5296,51343,5601,10393,8379,5290,8503,112,109,699,5600,51434,3320,994,2771,5567,113,993,207,3326,5295,107,5613,3845,9088,8697,995,983,64506,3630,8881,996,111,114,10000,29945,6300	ANAPC5,RAF1,RPS6KA1,CCNB1,MAPK14,PRKACA,PDE3A,ANAPC1,RPS6KA2,PIK3R5,PIK3R2,FZR1,MAPK9,ANAPC10,MAD1L1,PIK3CA,PIK3R3,ADCY6,ADCY3,BUB1,MAPK11,ANAPC7,HSP90AA1,CDC25B,GNAI2,PRKACB,ADCY7,CDC25A,AKT1,HSP90AB1,PIK3R1,ADCY1,PRKX,KRAS,PKMYT1,CDC23,CDC25C,CDK1,CPEB1,INS,CDC16,CDC27,ADCY5,ADCY8,AKT3,ANAPC4,MAPK12
ko04914	Progesterone-mediated oocyte maturation	0.0475448618105576	-3.04608155449285	86	47	0.0155013192612137	3032	6715	51433,5894,6195,891,1432,5566,5139,64682,6196,23533,5296,51343,5601,10393,8379,5290,8503,112,109,699,5600,51434,3320,994,2771,5567,113,993,207,3326,5295,107,5613,3845,9088,8697,995,983,64506,3630,8881,996,111,114,10000,29945,6300	ANAPC5,RAF1,RPS6KA1,CCNB1,MAPK14,PRKACA,PDE3A,ANAPC1,RPS6KA2,PIK3R5,PIK3R2,FZR1,MAPK9,ANAPC10,MAD1L1,PIK3CA,PIK3R3,ADCY6,ADCY3,BUB1,MAPK11,ANAPC7,HSP90AA1,CDC25B,GNAI2,PRKACB,ADCY7,CDC25A,AKT1,HSP90AB1,PIK3R1,ADCY1,PRKX,KRAS,PKMYT1,CDC23,CDC25C,CDK1,CPEB1,INS,CDC16,CDC27,ADCY5,ADCY8,AKT3,ANAPC4,MAPK12
hsa04917	Prolactin signaling pathway	0.048355329593029	-3.02917883372582	72	40	0.0131926121372032	3032	6715	399694,5894,8835,1432,6714,25759,595,1154,8651,6464,53358,23533,5618,2001,4790,5296,5601,5290,9306,8503,3717,5600,6774,8792,207,5295,3845,3973,2353,5605,3630,9021,2645,10000,3972,2932,6776,3265,6300,3659	SHC4,RAF1,SOCS2,MAPK14,SRC,SHC2,CCND1,CISH,SOCS1,SHC1,SHC3,PIK3R5,PRLR,ELF5,NFKB1,PIK3R2,MAPK9,PIK3CA,SOCS6,PIK3R3,JAK2,MAPK11,STAT3,TNFRSF11A,AKT1,PIK3R1,KRAS,LHCGR,FOS,MAP2K2,INS,SOCS3,GCK,AKT3,LHB,GSK3B,STAT5A,HRAS,MAPK12,IRF1
ko04917	Prolactin signaling pathway	0.048355329593029	-3.02917883372582	72	40	0.0131926121372032	3032	6715	399694,5894,8835,1432,6714,25759,595,1154,8651,6464,53358,23533,5618,2001,4790,5296,5601,5290,9306,8503,3717,5600,6774,8792,207,5295,3845,3973,2353,5605,3630,9021,2645,10000,3972,2932,6776,3265,6300,3659	SHC4,RAF1,SOCS2,MAPK14,SRC,SHC2,CCND1,CISH,SOCS1,SHC1,SHC3,PIK3R5,PRLR,ELF5,NFKB1,PIK3R2,MAPK9,PIK3CA,SOCS6,PIK3R3,JAK2,MAPK11,STAT3,TNFRSF11A,AKT1,PIK3R1,KRAS,LHCGR,FOS,MAP2K2,INS,SOCS3,GCK,AKT3,LHB,GSK3B,STAT5A,HRAS,MAPK12,IRF1
M00131	Inositol phosphate metabolism, Ins(1,3,4,5)P4 => Ins(1,3,4)P3 => myo-inositol	0.0506319380418818	-2.98317271520474	9	7	0.00230870712401055	3032	6715	3612,51763,3631,3632,54928,3613,8821	IMPA1,INPP5K,INPP4A,INPP5A,IMPAD1,IMPA2,INPP4B
hsa_M00361	Nucleotide sugar biosynthesis, eukaryotes	0.0506319380418818	-2.98317271520474	9	7	0.00230870712401055	3032	6715	29925,80146,7360,6675,29926,7358,2582	GMPPB,UXS1,UGP2,UAP1,GMPPA,UGDH,GALE
hsa_M00131	Inositol phosphate metabolism, Ins(1,3,4,5)P4 => Ins(1,3,4)P3 => myo-inositol	0.0506319380418818	-2.98317271520474	9	7	0.00230870712401055	3032	6715	3612,51763,3631,3632,54928,3613,8821	IMPA1,INPP5K,INPP4A,INPP5A,IMPAD1,IMPA2,INPP4B
M00361	Nucleotide sugar biosynthesis, eukaryotes	0.0506319380418818	-2.98317271520474	9	7	0.00230870712401055	3032	6715	29925,80146,7360,6675,29926,7358,2582	GMPPB,UXS1,UGP2,UAP1,GMPPA,UGDH,GALE
hsa04151	PI3K-Akt signaling pathway	0.056914345962243	-2.86620784375402	346	171	0.0563984168865435	3032	6715	7249,6256,2782,1026,7531,5578,23566,898,57521,3909,57121,7448,1280,4790,5296,5290,3566,5521,1977,5159,64223,3562,468,1019,2788,4170,672,7422,6009,5228,1969,59345,3688,4254,2932,5522,284,3918,5528,5563,253314,1388,2335,3655,5562,7059,23239,2688,1293,54541,3675,23533,2324,4609,1291,5105,3913,2264,28227,3915,2057,27006,1944,3845,4804,5605,1956,2248,3643,29941,1435,10161,7450,9180,7534,1942,64764,9134,1284,2475,5894,7148,2783,1441,595,5154,5518,3551,1289,2997,8503,22801,4233,8515,3694,3815,1386,1311,1292,207,2249,3326,1277,2257,10971,90993,3630,2260,2246,5515,8517,5529,5525,1945,1978,2321,5590,1946,3082,8115,6198,55844,3911,9170,1128,3565,9586,5585,284217,3914,2261,1440,3696,2793,5618,896,117145,6446,3717,51764,3320,63923,3672,1385,6850,6199,5170,56034,2254,148327,7143,1975,7058,3164,5295,2786,5747,3570,3454,3560,92579,200186,10000,8817,26281,356,51378,3685,3691,3265,1436	TSC2,RXRA,GNB1,CDKN1A,YWHAE,PRKCA,LPAR3,CCNE1,RPTOR,LAMA3,LPAR5,VTN,COL2A1,NFKB1,PIK3R2,PIK3CA,IL4R,PPP2R2B,EIF4E,PDGFRB,MLST8,IL3,ATF4,CDK4,GNG7,MCL1,BRCA1,VEGFA,RHEB,PGF,EPHA2,GNB4,ITGB1,KITLG,GSK3B,PPP2R2C,ANGPT1,LAMC2,PPP2R5D,PRKAA2,EIF4E1B,ATF6B,FN1,ITGA6,PRKAA1,THBS3,PHLPP1,GH1,COL6A3,DDIT4,ITGA3,PIK3R5,FLT4,MYC,COL6A1,PCK1,LAMB2,FGFR4,PPP2R3B,LAMC1,EPOR,FGF22,EFNA3,KRAS,NGFR,MAP2K2,EGFR,FGF3,INSR,PKN3,CSF1,LPAR6,VWF,OSMR,YWHAZ,EFNA1,CREB3L2,CCNE2,COL4A2,MTOR,RAF1,TNXB,GNB2,CSF3R,CCND1,PDGFA,PPP2R1A,IKBKB,COL5A1,GYS1,PIK3R3,ITGA11,MET,ITGA10,ITGB6,KIT,ATF2,COMP,COL6A2,AKT1,FGF4,HSP90AB1,COL1A1,FGF12,YWHAQ,CREB3L1,INS,FGFR1,FGF1,PPP2CA,IKBKG,PPP2R5E,PPP2R5A,EFNA4,EIF4EBP1,FLT1,PRKCZ,EFNA5,HGF,TCL1A,RPS6KB1,PPP2R2D,LAMA5,LPAR2,CHRM1,IL4,CREB5,PKN1,LAMA1,LAMB3,FGFR3,CSF3,ITGB8,GNGT2,PRLR,CCND3,THEM4,SGK1,JAK2,GNG13,HSP90AA1,TNN,ITGA1,CREB1,SYK,RPS6KB2,PDPK1,PDGFC,FGF9,CREB3L4,TNR,EIF4B,THBS2,NR4A1,PIK3R1,GNG4,PTK2,IL6R,IFNAR1,IL2RB,G6PC3,CRTC2,AKT3,FGF18,FGF20,FASLG,ANGPT4,ITGAV,ITGB4,HRAS,CSF1R
ko04151	PI3K-Akt signaling pathway	0.056914345962243	-2.86620784375402	346	171	0.0563984168865435	3032	6715	7249,6256,2782,1026,7531,5578,23566,898,57521,3909,57121,7448,1280,4790,5296,5290,3566,5521,1977,5159,64223,3562,468,1019,2788,4170,672,7422,6009,5228,1969,59345,3688,4254,2932,5522,284,3918,5528,5563,253314,1388,2335,3655,5562,7059,23239,2688,1293,54541,3675,23533,2324,4609,1291,5105,3913,2264,28227,3915,2057,27006,1944,3845,4804,5605,1956,2248,3643,29941,1435,10161,7450,9180,7534,1942,64764,9134,1284,2475,5894,7148,2783,1441,595,5154,5518,3551,1289,2997,8503,22801,4233,8515,3694,3815,1386,1311,1292,207,2249,3326,1277,2257,10971,90993,3630,2260,2246,5515,8517,5529,5525,1945,1978,2321,5590,1946,3082,8115,6198,55844,3911,9170,1128,3565,9586,5585,284217,3914,2261,1440,3696,2793,5618,896,117145,6446,3717,51764,3320,63923,3672,1385,6850,6199,5170,56034,2254,148327,7143,1975,7058,3164,5295,2786,5747,3570,3454,3560,92579,200186,10000,8817,26281,356,51378,3685,3691,3265,1436	TSC2,RXRA,GNB1,CDKN1A,YWHAE,PRKCA,LPAR3,CCNE1,RPTOR,LAMA3,LPAR5,VTN,COL2A1,NFKB1,PIK3R2,PIK3CA,IL4R,PPP2R2B,EIF4E,PDGFRB,MLST8,IL3,ATF4,CDK4,GNG7,MCL1,BRCA1,VEGFA,RHEB,PGF,EPHA2,GNB4,ITGB1,KITLG,GSK3B,PPP2R2C,ANGPT1,LAMC2,PPP2R5D,PRKAA2,EIF4E1B,ATF6B,FN1,ITGA6,PRKAA1,THBS3,PHLPP1,GH1,COL6A3,DDIT4,ITGA3,PIK3R5,FLT4,MYC,COL6A1,PCK1,LAMB2,FGFR4,PPP2R3B,LAMC1,EPOR,FGF22,EFNA3,KRAS,NGFR,MAP2K2,EGFR,FGF3,INSR,PKN3,CSF1,LPAR6,VWF,OSMR,YWHAZ,EFNA1,CREB3L2,CCNE2,COL4A2,MTOR,RAF1,TNXB,GNB2,CSF3R,CCND1,PDGFA,PPP2R1A,IKBKB,COL5A1,GYS1,PIK3R3,ITGA11,MET,ITGA10,ITGB6,KIT,ATF2,COMP,COL6A2,AKT1,FGF4,HSP90AB1,COL1A1,FGF12,YWHAQ,CREB3L1,INS,FGFR1,FGF1,PPP2CA,IKBKG,PPP2R5E,PPP2R5A,EFNA4,EIF4EBP1,FLT1,PRKCZ,EFNA5,HGF,TCL1A,RPS6KB1,PPP2R2D,LAMA5,LPAR2,CHRM1,IL4,CREB5,PKN1,LAMA1,LAMB3,FGFR3,CSF3,ITGB8,GNGT2,PRLR,CCND3,THEM4,SGK1,JAK2,GNG13,HSP90AA1,TNN,ITGA1,CREB1,SYK,RPS6KB2,PDPK1,PDGFC,FGF9,CREB3L4,TNR,EIF4B,THBS2,NR4A1,PIK3R1,GNG4,PTK2,IL6R,IFNAR1,IL2RB,G6PC3,CRTC2,AKT3,FGF18,FGF20,FASLG,ANGPT4,ITGAV,ITGB4,HRAS,CSF1R
ko04713	Circadian entrainment	0.0570468919097388	-2.8638816842679	97	52	0.0171503957783641	3032	6715	4544,3763,8912,2782,51655,5578,9252,5566,2783,9722,8864,5331,2890,51806,2793,112,109,5593,51764,1385,5330,4543,2771,8911,818,815,5567,113,2788,107,2902,5613,6262,2786,3710,2353,3762,817,3765,111,5187,59345,816,114,2983,3708,163688,5332,8863,55811,117,810	MTNR1B,KCNJ6,CACNA1H,GNB1,RASD1,PRKCA,RPS6KA5,PRKACA,GNB2,NOS1AP,PER2,PLCB3,GRIA1,CALML5,GNGT2,ADCY6,ADCY3,PRKG2,GNG13,CREB1,PLCB2,MTNR1A,GNAI2,CACNA1I,CAMK2G,CAMK2A,PRKACB,ADCY7,GNG7,ADCY1,GRIN1,PRKX,RYR2,GNG4,ITPR3,FOS,KCNJ5,CAMK2D,KCNJ9,ADCY5,PER1,GNB4,CAMK2B,ADCY8,GUCY1B3,ITPR1,CALML6,PLCB4,PER3,ADCY10,ADCYAP1R1,CALML3
hsa04713	Circadian entrainment	0.0570468919097388	-2.8638816842679	97	52	0.0171503957783641	3032	6715	4544,3763,8912,2782,51655,5578,9252,5566,2783,9722,8864,5331,2890,51806,2793,112,109,5593,51764,1385,5330,4543,2771,8911,818,815,5567,113,2788,107,2902,5613,6262,2786,3710,2353,3762,817,3765,111,5187,59345,816,114,2983,3708,163688,5332,8863,55811,117,810	MTNR1B,KCNJ6,CACNA1H,GNB1,RASD1,PRKCA,RPS6KA5,PRKACA,GNB2,NOS1AP,PER2,PLCB3,GRIA1,CALML5,GNGT2,ADCY6,ADCY3,PRKG2,GNG13,CREB1,PLCB2,MTNR1A,GNAI2,CACNA1I,CAMK2G,CAMK2A,PRKACB,ADCY7,GNG7,ADCY1,GRIN1,PRKX,RYR2,GNG4,ITPR3,FOS,KCNJ5,CAMK2D,KCNJ9,ADCY5,PER1,GNB4,CAMK2B,ADCY8,GUCY1B3,ITPR1,CALML6,PLCB4,PER3,ADCY10,ADCYAP1R1,CALML3
hsa00100	Steroid biosynthesis	0.0593907907239815	-2.82361610295003	20	13	0.00428759894459103	3032	6715	6646,1591,4047,10826,6307,120227,7108,6713,1056,51478,3988,1717,2222	SOAT1,CYP24A1,LSS,FAXDC2,MSMO1,CYP2R1,TM7SF2,SQLE,CEL,HSD17B7,LIPA,DHCR7,FDFT1
ko00100	Steroid biosynthesis	0.0593907907239815	-2.82361610295003	20	13	0.00428759894459103	3032	6715	6646,1591,4047,10826,6307,120227,6713,7108,1056,51478,1717,3988,2222	SOAT1,CYP24A1,LSS,FAXDC2,MSMO1,CYP2R1,SQLE,TM7SF2,CEL,HSD17B7,DHCR7,LIPA,FDFT1
hsa00310	Lysine degradation	0.0610633391311206	-2.79584360710577	49	28	0.00923482849604222	3032	6715	55870,8085,79813,55753,5351,23127,79709,54904,4967,219,58508,2639,80854,1743,84444,64324,51111,83852,84787,10919,79723,3033,5352,387893,9757,501,224,9869	ASH1L,KMT2D,EHMT1,OGDHL,PLOD1,COLGALT2,COLGALT1,WHSC1L1,OGDH,ALDH1B1,KMT2C,GCDH,SETD7,DLST,DOT1L,NSD1,SUV420H1,SETDB2,SUV420H2,EHMT2,SUV39H2,HADH,PLOD2,SETD8,KMT2B,ALDH7A1,ALDH3A2,SETDB1
ko00310	Lysine degradation	0.0610633391311206	-2.79584360710577	49	28	0.00923482849604222	3032	6715	8085,55870,79813,55753,79709,5351,23127,54904,4967,219,80854,2639,58508,1743,84444,64324,51111,3033,79723,10919,84787,83852,5352,387893,9757,501,224,9869	KMT2D,ASH1L,EHMT1,OGDHL,COLGALT1,PLOD1,COLGALT2,WHSC1L1,OGDH,ALDH1B1,SETD7,GCDH,KMT2C,DLST,DOT1L,NSD1,SUV420H1,HADH,SUV39H2,EHMT2,SUV420H2,SETDB2,PLOD2,SETD8,KMT2B,ALDH7A1,ALDH3A2,SETDB1
hsa04340	Hedgehog signaling pathway	0.0614335440802012	-2.78979927248332	51	29	0.0095646437994723	3032	6715	1455,23291,7483,2736,1454,7476,7472,5727,5613,7477,7481,1452,5566,2619,7478,650,54361,7475,80326,53944,81029,6469,2932,89780,1456,1453,7484,8945,5567	CSNK1G2,FBXW11,WNT9A,GLI2,CSNK1E,WNT7A,WNT2,PTCH1,PRKX,WNT7B,WNT11,CSNK1A1,PRKACA,GAS1,WNT8A,BMP2,WNT4,WNT6,WNT10A,CSNK1G1,WNT5B,SHH,GSK3B,WNT3A,CSNK1G3,CSNK1D,WNT9B,BTRC,PRKACB
ko04340	Hedgehog signaling pathway	0.0614335440802012	-2.78979927248332	51	29	0.0095646437994723	3032	6715	1455,23291,7483,2736,1454,7476,7472,5727,5613,7477,7481,1452,5566,2619,7478,650,54361,7475,80326,53944,81029,6469,2932,89780,1456,1453,7484,8945,5567	CSNK1G2,FBXW11,WNT9A,GLI2,CSNK1E,WNT7A,WNT2,PTCH1,PRKX,WNT7B,WNT11,CSNK1A1,PRKACA,GAS1,WNT8A,BMP2,WNT4,WNT6,WNT10A,CSNK1G1,WNT5B,SHH,GSK3B,WNT3A,CSNK1G3,CSNK1D,WNT9B,BTRC,PRKACB
ko05130	Pathogenic Escherichia coli infection	0.0619278961093364	-2.78178453668518	55	31	0.0102242744063325	3032	6715	7280,81873,71,4690,10383,10971,4691,929,84617,112714,5578,10552,10376,25,7454,7278,2534,999,1499,10092,51807,3688,9181,7534,60,6093,2017,347688,7100,10381,7277	TUBB2A,ARPC5L,ACTG1,NCK1,TUBB4B,YWHAQ,NCL,CD14,TUBB6,TUBA3E,PRKCA,ARPC1A,TUBA1B,ABL1,WAS,TUBA3C,FYN,CDH1,CTNNB1,ARPC5,TUBA8,ITGB1,ARHGEF2,YWHAZ,ACTB,ROCK1,CTTN,TUBB8,TLR5,TUBB3,TUBA4A
hsa05130	Pathogenic Escherichia coli infection	0.0619278961093364	-2.78178453668518	55	31	0.0102242744063325	3032	6715	7280,81873,71,4690,10383,10971,4691,929,84617,112714,5578,10552,10376,25,7454,7278,2534,999,1499,10092,51807,3688,9181,7534,60,6093,2017,347688,7100,10381,7277	TUBB2A,ARPC5L,ACTG1,NCK1,TUBB4B,YWHAQ,NCL,CD14,TUBB6,TUBA3E,PRKCA,ARPC1A,TUBA1B,ABL1,WAS,TUBA3C,FYN,CDH1,CTNNB1,ARPC5,TUBA8,ITGB1,ARHGEF2,YWHAZ,ACTB,ROCK1,CTTN,TUBB8,TLR5,TUBB3,TUBA4A
hsa05221	Acute myeloid leukemia	0.0620675968632422	-2.77953121586412	57	32	0.0105540897097625	3032	6715	5914,207,3728,7704,2475,5894,5295,3845,6932,5605,6934,595,83439,8517,23533,1978,4609,10000,3551,4790,5296,5290,8503,6198,6776,5292,861,6774,6688,3815,3265,6199	RARA,AKT1,JUP,ZBTB16,MTOR,RAF1,PIK3R1,KRAS,TCF7,MAP2K2,TCF7L2,CCND1,TCF7L1,IKBKG,PIK3R5,EIF4EBP1,MYC,AKT3,IKBKB,NFKB1,PIK3R2,PIK3CA,PIK3R3,RPS6KB1,STAT5A,PIM1,RUNX1,STAT3,SPI1,KIT,HRAS,RPS6KB2
ko05221	Acute myeloid leukemia	0.0620675968632422	-2.77953121586412	57	32	0.0105540897097625	3032	6715	5914,207,3728,7704,2475,5894,5295,3845,6932,5605,6934,595,83439,8517,23533,1978,4609,10000,3551,4790,5296,5290,8503,6198,6776,5292,861,6774,6688,3815,3265,6199	RARA,AKT1,JUP,ZBTB16,MTOR,RAF1,PIK3R1,KRAS,TCF7,MAP2K2,TCF7L2,CCND1,TCF7L1,IKBKG,PIK3R5,EIF4EBP1,MYC,AKT3,IKBKB,NFKB1,PIK3R2,PIK3CA,PIK3R3,RPS6KB1,STAT5A,PIM1,RUNX1,STAT3,SPI1,KIT,HRAS,RPS6KB2
hsa05131	Shigellosis	0.0621650426530612	-2.77796245245085	61	34	0.0112137203166227	3032	6715	10163,391,23291,81873,71,1793,1432,6714,1399,25,10092,5216,3551,4790,5601,5600,2017,960,7414,345456,10552,1729,8517,7454,3576,4792,7322,3688,64127,60,6093,9474,8945,6300	WASF2,RHOG,FBXW11,ARPC5L,ACTG1,DOCK1,MAPK14,SRC,CRKL,ABL1,ARPC5,PFN1,IKBKB,NFKB1,MAPK9,MAPK11,CTTN,CD44,VCL,PFN3,ARPC1A,DIAPH1,IKBKG,WAS,IL8,NFKBIA,UBE2D2,ITGB1,NOD2,ACTB,ROCK1,ATG5,BTRC,MAPK12
hsa_M00130	Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4	0.0631680150381328	-2.76195719710547	22	14	0.00461741424802111	3032	6715	55300,3707,5335,89869,5298,5333,5336,5332,113026,8394,5330,23396,55361,5331	PI4K2B,ITPKB,PLCG1,PLCZ1,PI4KB,PLCD1,PLCG2,PLCB4,PLCD3,PIP5K1A,PLCB2,PIP5K1C,PI4K2A,PLCB3
M00130	Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4	0.0631680150381328	-2.76195719710547	22	14	0.00461741424802111	3032	6715	55300,3707,5335,89869,5298,5333,5336,5332,113026,8394,5330,23396,55361,5331	PI4K2B,ITPKB,PLCG1,PLCZ1,PI4KB,PLCD1,PLCG2,PLCB4,PLCD3,PIP5K1A,PLCB2,PIP5K1C,PI4K2A,PLCB3
M00109	C21-Steroid hormone biosynthesis, progesterone => cortisol/cortisone	0.0701476729520989	-2.65715264544149	6	5	0.0016490765171504	3032	6715	1584,1589,3290,3291,1585	CYP11B1,CYP21A2,HSD11B1,HSD11B2,CYP11B2
hsa_M00109	C21-Steroid hormone biosynthesis, progesterone => cortisol/cortisone	0.0701476729520989	-2.65715264544149	6	5	0.0016490765171504	3032	6715	1584,1589,3290,3291,1585	CYP11B1,CYP21A2,HSD11B1,HSD11B2,CYP11B2
M00058	Glycosaminoglycan biosynthesis, chondroitin sulfate backbone	0.0701476729520989	-2.65715264544149	6	5	0.0016490765171504	3032	6715	337876,22856,55454,55790,79586	CHSY3,CHSY1,CSGALNACT2,CSGALNACT1,CHPF
hsa_M00058	Glycosaminoglycan biosynthesis, chondroitin sulfate backbone	0.0701476729520989	-2.65715264544149	6	5	0.0016490765171504	3032	6715	337876,22856,55454,55790,79586	CHSY3,CHSY1,CSGALNACT2,CSGALNACT1,CHPF
ko04640	Hematopoietic cell lineage	0.0726172404985245	-2.62255291291204	88	47	0.0155013192612137	3032	6715	920,3655,911,3565,2812,7173,912,924,909,7037,1441,921,3123,913,1440,3675,2209,933,928,3566,960,3672,3815,3562,1604,3590,2057,7066,2815,1380,929,3570,952,1437,2323,948,290,3554,925,1378,1435,4254,947,3581,3567,4311,1436	CD4,ITGA6,CD1C,IL4,GP1BB,TPO,CD1D,CD7,CD1A,TFRC,CSF3R,CD5,HLA-DRB1,CD1E,CSF3,ITGA3,FCGR1A,CD22,CD9,IL4R,CD44,ITGA1,KIT,IL3,CD55,IL11RA,EPOR,THPO,GP9,CR2,CD14,IL6R,CD38,CSF2,FLT3LG,CD36,ANPEP,IL1R1,CD8A,CR1,CSF1,KITLG,CD34,IL9R,IL5,MME,CSF1R
hsa04640	Hematopoietic cell lineage	0.0726172404985245	-2.62255291291204	88	47	0.0155013192612137	3032	6715	920,3655,911,3565,2812,7173,912,924,909,7037,1441,921,3123,913,1440,3675,2209,933,928,3566,960,3672,3815,3562,1604,3590,2057,7066,2815,1380,929,3570,952,1437,2323,948,290,3554,925,1378,1435,4254,947,3581,3567,4311,1436	CD4,ITGA6,CD1C,IL4,GP1BB,TPO,CD1D,CD7,CD1A,TFRC,CSF3R,CD5,HLA-DRB1,CD1E,CSF3,ITGA3,FCGR1A,CD22,CD9,IL4R,CD44,ITGA1,KIT,IL3,CD55,IL11RA,EPOR,THPO,GP9,CR2,CD14,IL6R,CD38,CSF2,FLT3LG,CD36,ANPEP,IL1R1,CD8A,CR1,CSF1,KITLG,CD34,IL9R,IL5,MME,CSF1R
ko00051	Fructose and mannose metabolism	0.0773204841385288	-2.55979636317003	36	21	0.00692612137203166	3032	6715	5210,197258,7264,5208,57016,5209,80201,5373,29926,5372,57103,5211,226,3099,29925,3098,2762,8776,3101,29085,3795	PFKFB4,FUK,TSTA3,PFKFB2,AKR1B10,PFKFB3,HKDC1,PMM2,GMPPA,PMM1,C12orf5,PFKL,ALDOA,HK2,GMPPB,HK1,GMDS,MTMR1,HK3,PHPT1,KHK
hsa00051	Fructose and mannose metabolism	0.0773204841385288	-2.55979636317003	36	21	0.00692612137203166	3032	6715	5210,197258,7264,5208,57016,5209,80201,5373,29926,5372,57103,5211,226,3099,29925,3098,2762,3101,8776,29085,3795	PFKFB4,FUK,TSTA3,PFKFB2,AKR1B10,PFKFB3,HKDC1,PMM2,GMPPA,PMM1,C12orf5,PFKL,ALDOA,HK2,GMPPB,HK1,GMDS,HK3,MTMR1,PHPT1,KHK
hsa05120	Epithelial cell signaling in Helicobacter pylori infection	0.0781754180162582	-2.54880002846662	68	37	0.0122031662269129	3032	6715	1839,537,90423,50848,7082,28964,4067,1432,6714,525,3725,533,3551,5336,4790,5601,5781,5600,4233,51606,9020,9114,9550,5058,6868,83700,1956,8517,5335,10312,3576,4792,127124,527,528,8992,6300	HBEGF,ATP6AP1,ATP6V1E2,F11R,TJP1,GIT1,LYN,MAPK14,SRC,ATP6V1B1,JUN,ATP6V0B,IKBKB,PLCG2,NFKB1,MAPK9,PTPN11,MAPK11,MET,ATP6V1H,MAP3K14,ATP6V0D1,ATP6V1G1,PAK1,ADAM17,JAM3,EGFR,IKBKG,PLCG1,TCIRG1,IL8,NFKBIA,ATP6V1G3,ATP6V0C,ATP6V1C1,ATP6V0E1,MAPK12
ko05120	Epithelial cell signaling in Helicobacter pylori infection	0.0781754180162582	-2.54880002846662	68	37	0.0122031662269129	3032	6715	1839,537,90423,50848,7082,28964,4067,1432,6714,525,3725,533,3551,5336,4790,5601,5781,5600,4233,51606,9020,9114,9550,5058,6868,83700,1956,8517,5335,10312,3576,4792,127124,527,528,8992,6300	HBEGF,ATP6AP1,ATP6V1E2,F11R,TJP1,GIT1,LYN,MAPK14,SRC,ATP6V1B1,JUN,ATP6V0B,IKBKB,PLCG2,NFKB1,MAPK9,PTPN11,MAPK11,MET,ATP6V1H,MAP3K14,ATP6V0D1,ATP6V1G1,PAK1,ADAM17,JAM3,EGFR,IKBKG,PLCG1,TCIRG1,IL8,NFKBIA,ATP6V1G3,ATP6V0C,ATP6V1C1,ATP6V0E1,MAPK12
ko05211	Renal cell carcinoma	0.0786087111113273	-2.5432727572996	66	36	0.0118733509234828	3032	6715	2034,5894,6513,7042,2113,10298,56924,3725,1399,23533,5296,5781,5290,8503,9915,4233,5058,2889,207,6923,9978,7039,5295,2271,6921,3845,7422,5605,112398,3091,10000,8453,3082,3265,405,54583	EPAS1,RAF1,SLC2A1,TGFB2,ETS1,PAK4,PAK6,JUN,CRKL,PIK3R5,PIK3R2,PTPN11,PIK3CA,PIK3R3,ARNT2,MET,PAK1,RAPGEF1,AKT1,TCEB2,RBX1,TGFA,PIK3R1,FH,TCEB1,KRAS,VEGFA,MAP2K2,EGLN2,HIF1A,AKT3,CUL2,HGF,HRAS,ARNT,EGLN1
hsa05211	Renal cell carcinoma	0.0786087111113273	-2.5432727572996	66	36	0.0118733509234828	3032	6715	2034,5894,6513,7042,2113,10298,56924,3725,1399,23533,5296,5781,5290,8503,9915,4233,5058,2889,207,6923,9978,7039,5295,2271,6921,3845,7422,5605,112398,3091,10000,8453,3082,3265,405,54583	EPAS1,RAF1,SLC2A1,TGFB2,ETS1,PAK4,PAK6,JUN,CRKL,PIK3R5,PIK3R2,PTPN11,PIK3CA,PIK3R3,ARNT2,MET,PAK1,RAPGEF1,AKT1,TCEB2,RBX1,TGFA,PIK3R1,FH,TCEB1,KRAS,VEGFA,MAP2K2,EGLN2,HIF1A,AKT3,CUL2,HGF,HRAS,ARNT,EGLN1
hsa04150	mTOR signaling pathway	0.0796852146095813	-2.52967122344983	60	33	0.0108839050131926	3032	6715	5563,253314,7249,2475,92335,6195,5562,8408,5578,54541,57521,6196,23533,3551,5296,5290,8503,1977,6199,64223,5170,25989,1975,207,5295,7422,9706,3630,6009,3091,10000,1978,6198	PRKAA2,EIF4E1B,TSC2,MTOR,STRADA,RPS6KA1,PRKAA1,ULK1,PRKCA,DDIT4,RPTOR,RPS6KA2,PIK3R5,IKBKB,PIK3R2,PIK3CA,PIK3R3,EIF4E,RPS6KB2,MLST8,PDPK1,ULK3,EIF4B,AKT1,PIK3R1,VEGFA,ULK2,INS,RHEB,HIF1A,AKT3,EIF4EBP1,RPS6KB1
ko04150	mTOR signaling pathway	0.0796852146095813	-2.52967122344983	60	33	0.0108839050131926	3032	6715	5563,253314,7249,2475,92335,6195,5562,8408,5578,54541,57521,6196,23533,3551,5296,5290,8503,1977,6199,64223,5170,25989,1975,207,5295,7422,9706,3630,6009,3091,10000,1978,6198	PRKAA2,EIF4E1B,TSC2,MTOR,STRADA,RPS6KA1,PRKAA1,ULK1,PRKCA,DDIT4,RPTOR,RPS6KA2,PIK3R5,IKBKB,PIK3R2,PIK3CA,PIK3R3,EIF4E,RPS6KB2,MLST8,PDPK1,ULK3,EIF4B,AKT1,PIK3R1,VEGFA,ULK2,INS,RHEB,HIF1A,AKT3,EIF4EBP1,RPS6KB1
hsa05215	Prostate cancer	0.0881605821903905	-2.42859532980634	89	47	0.0155013192612137	3032	6715	9134,64764,2475,5894,6716,2064,1026,9586,2950,898,5154,595,1499,23533,3551,4790,5296,5290,8503,3320,1385,5159,5170,56034,148327,468,207,7039,3326,5295,1871,90993,6932,3845,5605,1956,3630,2260,6934,8517,83439,10000,4792,3645,2932,1870,3265	CCNE2,CREB3L2,MTOR,RAF1,SRD5A2,ERBB2,CDKN1A,CREB5,GSTP1,CCNE1,PDGFA,CCND1,CTNNB1,PIK3R5,IKBKB,NFKB1,PIK3R2,PIK3CA,PIK3R3,HSP90AA1,CREB1,PDGFRB,PDPK1,PDGFC,CREB3L4,ATF4,AKT1,TGFA,HSP90AB1,PIK3R1,E2F3,CREB3L1,TCF7,KRAS,MAP2K2,EGFR,INS,FGFR1,TCF7L2,IKBKG,TCF7L1,AKT3,NFKBIA,INSRR,GSK3B,E2F2,HRAS
ko05215	Prostate cancer	0.0881605821903905	-2.42859532980634	89	47	0.0155013192612137	3032	6715	9134,64764,2475,5894,6716,2064,1026,9586,2950,898,5154,595,1499,23533,3551,4790,5296,5290,8503,3320,1385,5159,5170,56034,148327,468,207,7039,3326,5295,1871,90993,6932,3845,5605,1956,3630,2260,6934,8517,83439,10000,4792,3645,2932,1870,3265	CCNE2,CREB3L2,MTOR,RAF1,SRD5A2,ERBB2,CDKN1A,CREB5,GSTP1,CCNE1,PDGFA,CCND1,CTNNB1,PIK3R5,IKBKB,NFKB1,PIK3R2,PIK3CA,PIK3R3,HSP90AA1,CREB1,PDGFRB,PDPK1,PDGFC,CREB3L4,ATF4,AKT1,TGFA,HSP90AB1,PIK3R1,E2F3,CREB3L1,TCF7,KRAS,MAP2K2,EGFR,INS,FGFR1,TCF7L2,IKBKG,TCF7L1,AKT3,NFKBIA,INSRR,GSK3B,E2F2,HRAS
M00428	eIF4F complex	0.0897655395835145	-2.41055412360946	8	6	0.00197889182058048	3032	6715	8672,1981,1973,253314,1982,1977	EIF4G3,EIF4G1,EIF4A1,EIF4E1B,EIF4G2,EIF4E
hsa_M00428	eIF4F complex	0.0897655395835145	-2.41055412360946	8	6	0.00197889182058048	3032	6715	8672,1981,1973,253314,1982,1977	EIF4G3,EIF4G1,EIF4A1,EIF4E1B,EIF4G2,EIF4E
hsa_M00108	C21-Steroid hormone biosynthesis, progesterone => corticosterone/aldosterone	0.092005493834661	-2.38590698812186	3	3	0.000989445910290238	3032	6715	1584,1589,1585	CYP11B1,CYP21A2,CYP11B2
M00108	C21-Steroid hormone biosynthesis, progesterone => corticosterone/aldosterone	0.092005493834661	-2.38590698812186	3	3	0.000989445910290238	3032	6715	1584,1589,1585	CYP11B1,CYP21A2,CYP11B2
ko04120	Ubiquitin mediated proteolysis	0.0927606949842982	-2.3777322743385	137	70	0.0230870712401055	3032	6715	5071,23291,7189,7325,7317,57448,55585,7329,329,51366,64682,8554,389898,8651,6477,51343,10393,7326,55294,26091,51434,140739,330,6923,9978,991,868,8452,118424,672,8697,867,9021,10401,8881,7320,6500,10477,8924,51588,7323,51433,26272,63893,8916,7337,55070,11059,89910,7327,1643,9616,7328,6921,84447,10277,4591,7324,64326,9817,996,326,8453,7322,23221,27338,11065,1642,8945,29945	PARK2,FBXW11,TRAF6,UBE2E2,UBA1,BIRC6,UBE2Q1,UBE2I,BIRC2,UBR5,ANAPC1,PIAS1,UBE2NL,SOCS1,SIAH1,FZR1,ANAPC10,UBE2G1,FBXW7,HERC4,ANAPC7,UBE2F,BIRC3,TCEB2,RBX1,CDC20,CBLB,CUL3,UBE2J2,BRCA1,CDC23,CBL,SOCS3,PIAS3,CDC16,UBE2B,SKP1,UBE2E3,HERC2,PIAS4,UBE2D3,ANAPC5,FBXO4,UBE2O,HERC3,UBE3A,DET1,WWP1,UBE3B,UBE2G2,DDB2,RNF7,UBE2H,TCEB1,SYVN1,UBE4B,TRIM37,UBE2E1,RFWD2,KEAP1,CDC27,AIRE,CUL2,UBE2D2,RHOBTB2,UBE2S,UBE2C,DDB1,BTRC,ANAPC4
hsa04120	Ubiquitin mediated proteolysis	0.0927606949842982	-2.3777322743385	137	70	0.0230870712401055	3032	6715	5071,23291,7189,7325,7317,57448,55585,7329,329,51366,64682,8554,389898,8651,6477,51343,10393,7326,55294,26091,51434,140739,330,6923,9978,991,868,8452,118424,672,8697,867,9021,10401,8881,7320,6500,10477,8924,51588,7323,51433,26272,63893,8916,7337,55070,11059,89910,7327,1643,9616,7328,6921,84447,10277,4591,7324,64326,9817,996,326,8453,7322,23221,27338,11065,1642,8945,29945	PARK2,FBXW11,TRAF6,UBE2E2,UBA1,BIRC6,UBE2Q1,UBE2I,BIRC2,UBR5,ANAPC1,PIAS1,UBE2NL,SOCS1,SIAH1,FZR1,ANAPC10,UBE2G1,FBXW7,HERC4,ANAPC7,UBE2F,BIRC3,TCEB2,RBX1,CDC20,CBLB,CUL3,UBE2J2,BRCA1,CDC23,CBL,SOCS3,PIAS3,CDC16,UBE2B,SKP1,UBE2E3,HERC2,PIAS4,UBE2D3,ANAPC5,FBXO4,UBE2O,HERC3,UBE3A,DET1,WWP1,UBE3B,UBE2G2,DDB2,RNF7,UBE2H,TCEB1,SYVN1,UBE4B,TRIM37,UBE2E1,RFWD2,KEAP1,CDC27,AIRE,CUL2,UBE2D2,RHOBTB2,UBE2S,UBE2C,DDB1,BTRC,ANAPC4
hsa04114	Oocyte meiosis	0.0936942523381468	-2.36771843272756	110	57	0.0187994722955145	3032	6715	9134,23291,51433,89869,6195,7531,891,5566,898,26271,64682,6196,51806,5518,10393,112,109,699,51434,5499,818,815,5567,113,9978,991,107,10971,5613,9088,8697,3710,995,983,64506,3630,5515,5529,817,8881,996,5525,111,114,816,3708,163688,8243,6500,7534,5533,151648,810,5528,29945,8945,6300	CCNE2,FBXW11,ANAPC5,PLCZ1,RPS6KA1,YWHAE,CCNB1,PRKACA,CCNE1,FBXO5,ANAPC1,RPS6KA2,CALML5,PPP2R1A,ANAPC10,ADCY6,ADCY3,BUB1,ANAPC7,PPP1CA,CAMK2G,CAMK2A,PRKACB,ADCY7,RBX1,CDC20,ADCY1,YWHAQ,PRKX,PKMYT1,CDC23,ITPR3,CDC25C,CDK1,CPEB1,INS,PPP2CA,PPP2R5E,CAMK2D,CDC16,CDC27,PPP2R5A,ADCY5,ADCY8,CAMK2B,ITPR1,CALML6,SMC1A,SKP1,YWHAZ,PPP3CC,SGOL1,CALML3,PPP2R5D,ANAPC4,BTRC,MAPK12
ko04114	Oocyte meiosis	0.0936942523381468	-2.36771843272756	110	57	0.0187994722955145	3032	6715	9134,23291,51433,89869,6195,7531,891,5566,898,26271,64682,6196,51806,5518,10393,112,109,699,51434,5499,818,815,5567,113,9978,991,107,10971,5613,9088,8697,3710,995,983,64506,3630,5515,5529,817,8881,996,5525,111,114,816,3708,163688,8243,6500,7534,5533,151648,810,5528,29945,8945,6300	CCNE2,FBXW11,ANAPC5,PLCZ1,RPS6KA1,YWHAE,CCNB1,PRKACA,CCNE1,FBXO5,ANAPC1,RPS6KA2,CALML5,PPP2R1A,ANAPC10,ADCY6,ADCY3,BUB1,ANAPC7,PPP1CA,CAMK2G,CAMK2A,PRKACB,ADCY7,RBX1,CDC20,ADCY1,YWHAQ,PRKX,PKMYT1,CDC23,ITPR3,CDC25C,CDK1,CPEB1,INS,PPP2CA,PPP2R5E,CAMK2D,CDC16,CDC27,PPP2R5A,ADCY5,ADCY8,CAMK2B,ITPR1,CALML6,SMC1A,SKP1,YWHAZ,PPP3CC,SGOL1,CALML3,PPP2R5D,ANAPC4,BTRC,MAPK12
hsa04068	FoxO signaling pathway	0.0952249792274643	-2.35151298475911	133	68	0.0224274406332454	3032	6715	7874,5564,5897,5894,5565,51701,1026,891,1432,595,114907,3551,5296,10733,5290,8503,1032,901,1263,207,1454,9140,8743,11345,3586,80854,3630,53632,23710,4088,4087,4616,4089,6300,5563,10365,5562,3276,7046,7042,7048,9456,23533,5601,5105,6446,5600,664,26260,6774,5170,5295,9455,8698,3845,92579,5605,8471,1956,9454,847,51422,3643,1647,10000,356,472,3265	USP7,PRKAB1,RAG2,RAF1,PRKAB2,NLK,CDKN1A,CCNB1,MAPK14,CCND1,FBXO32,IKBKB,PIK3R2,PLK4,PIK3CA,PIK3R3,CDKN2D,CCNG2,PLK3,AKT1,CSNK1E,ATG12,TNFSF10,GABARAPL2,IL10,SETD7,INS,PRKAG3,GABARAPL1,SMAD3,SMAD2,GADD45B,SMAD4,MAPK12,PRKAA2,KLF2,PRKAA1,PRMT1,TGFBR1,TGFB2,TGFBR2,HOMER1,PIK3R5,MAPK9,PCK1,SGK1,MAPK11,BNIP3,FBXO25,STAT3,PDPK1,PIK3R1,HOMER2,S1PR4,KRAS,G6PC3,MAP2K2,IRS4,EGFR,HOMER3,CAT,PRKAG2,INSR,GADD45A,AKT3,FASLG,ATM,HRAS
hsa_M00001	Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate	0.0982390723626004	-2.32035125719099	25	15	0.00494722955145119	3032	6715	2597,2645,5211,5230,5313,226,3099,80201,5224,3098,2821,83440,5315,3101,2023	GAPDH,GCK,PFKL,PGK1,PKLR,ALDOA,HK2,HKDC1,PGAM2,HK1,GPI,ADPGK,PKM,HK3,ENO1
M00001	Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate	0.0982390723626004	-2.32035125719099	25	15	0.00494722955145119	3032	6715	2597,2645,5211,5230,5313,226,3099,80201,5224,3098,2821,83440,5315,3101,2023	GAPDH,GCK,PFKL,PGK1,PKLR,ALDOA,HK2,HKDC1,PGAM2,HK1,GPI,ADPGK,PKM,HK3,ENO1
hsa05214	Glioma	0.0987841067850266	-2.31481854966781	65	35	0.0115435356200528	3032	6715	399694,2475,5894,1026,5578,25759,5154,595,51806,6464,53358,23533,5336,5296,5290,8503,818,815,5159,207,7039,1019,5295,1871,3845,5605,1956,817,5335,10000,816,163688,1870,3265,810	SHC4,MTOR,RAF1,CDKN1A,PRKCA,SHC2,PDGFA,CCND1,CALML5,SHC1,SHC3,PIK3R5,PLCG2,PIK3R2,PIK3CA,PIK3R3,CAMK2G,CAMK2A,PDGFRB,AKT1,TGFA,CDK4,PIK3R1,E2F3,KRAS,MAP2K2,EGFR,CAMK2D,PLCG1,AKT3,CAMK2B,CALML6,E2F2,HRAS,CALML3
ko05214	Glioma	0.0987841067850266	-2.31481854966781	65	35	0.0115435356200528	3032	6715	399694,2475,5894,1026,5578,25759,5154,595,51806,6464,53358,23533,5336,5296,5290,8503,818,815,5159,207,7039,1019,5295,1871,3845,5605,1956,817,5335,10000,816,163688,1870,3265,810	SHC4,MTOR,RAF1,CDKN1A,PRKCA,SHC2,PDGFA,CCND1,CALML5,SHC1,SHC3,PIK3R5,PLCG2,PIK3R2,PIK3CA,PIK3R3,CAMK2G,CAMK2A,PDGFRB,AKT1,TGFA,CDK4,PIK3R1,E2F3,KRAS,MAP2K2,EGFR,CAMK2D,PLCG1,AKT3,CAMK2B,CALML6,E2F2,HRAS,CALML3
ko05217	Basal cell carcinoma	0.102394907216588	-2.27891830182653	55	30	0.00989445910290238	3032	6715	7483,2736,8325,11211,7476,7472,5727,6932,7477,324,7481,8323,6934,7478,650,83439,54361,7475,1499,8312,80326,81029,6469,2932,1855,7855,89780,1856,7484,8321	WNT9A,GLI2,FZD8,FZD10,WNT7A,WNT2,PTCH1,TCF7,WNT7B,APC,WNT11,FZD6,TCF7L2,WNT8A,BMP2,TCF7L1,WNT4,WNT6,CTNNB1,AXIN1,WNT10A,WNT5B,SHH,GSK3B,DVL1,FZD5,WNT3A,DVL2,WNT9B,FZD1
hsa05217	Basal cell carcinoma	0.102394907216588	-2.27891830182653	55	30	0.00989445910290238	3032	6715	7483,2736,8325,11211,7476,7472,5727,6932,7477,324,7481,8323,6934,7478,650,83439,54361,7475,1499,8312,80326,81029,6469,2932,1855,7855,89780,1856,7484,8321	WNT9A,GLI2,FZD8,FZD10,WNT7A,WNT2,PTCH1,TCF7,WNT7B,APC,WNT11,FZD6,TCF7L2,WNT8A,BMP2,TCF7L1,WNT4,WNT6,CTNNB1,AXIN1,WNT10A,WNT5B,SHH,GSK3B,DVL1,FZD5,WNT3A,DVL2,WNT9B,FZD1
ko04973	Carbohydrate digestion and absorption	0.104686138301089	-2.25678856432052	45	25	0.00824538258575198	3032	6715	207,5295,480,6476,80201,481,92579,80834,6523,476,2542,486,23533,10000,5296,346562,5290,83756,3099,8503,3098,3101,5330,477,478	AKT1,PIK3R1,ATP1A4,SI,HKDC1,ATP1B1,G6PC3,TAS1R2,SLC5A1,ATP1A1,SLC37A4,FXYD2,PIK3R5,AKT3,PIK3R2,GNAT3,PIK3CA,TAS1R3,HK2,PIK3R3,HK1,HK3,PLCB2,ATP1A2,ATP1A3
hsa04973	Carbohydrate digestion and absorption	0.104686138301089	-2.25678856432052	45	25	0.00824538258575198	3032	6715	207,5295,480,6476,80201,481,92579,80834,6523,476,2542,486,23533,10000,5296,346562,5290,83756,3099,8503,3098,3101,5330,477,478	AKT1,PIK3R1,ATP1A4,SI,HKDC1,ATP1B1,G6PC3,TAS1R2,SLC5A1,ATP1A1,SLC37A4,FXYD2,PIK3R5,AKT3,PIK3R2,GNAT3,PIK3CA,TAS1R3,HK2,PIK3R3,HK1,HK3,PLCB2,ATP1A2,ATP1A3
hsa04512	ECM-receptor interaction	0.108397651679517	-2.22194885368434	86	45	0.0148416886543536	3032	6715	1284,2335,375790,3339,3655,6385,7148,2812,7059,284217,6382,1293,3914,3909,3696,3675,7448,1291,1280,1289,3913,22801,63923,960,3672,8515,3694,1311,3161,1292,3915,7143,7058,9900,1277,2815,948,1605,3688,7450,51206,3685,3691,3911,3918	COL4A2,FN1,AGRN,HSPG2,ITGA6,SDC4,TNXB,GP1BB,THBS3,LAMA1,SDC1,COL6A3,LAMB3,LAMA3,ITGB8,ITGA3,VTN,COL6A1,COL2A1,COL5A1,LAMB2,ITGA11,TNN,CD44,ITGA1,ITGA10,ITGB6,COMP,HMMR,COL6A2,LAMC1,TNR,THBS2,SV2A,COL1A1,GP9,CD36,DAG1,ITGB1,VWF,GP6,ITGAV,ITGB4,LAMA5,LAMC2
ko04512	ECM-receptor interaction	0.108397651679517	-2.22194885368434	86	45	0.0148416886543536	3032	6715	1284,2335,375790,3339,3655,6385,7148,2812,7059,284217,6382,1293,3914,3909,3696,3675,7448,1291,1280,1289,3913,22801,63923,960,3672,8515,3694,1311,3161,1292,3915,7143,7058,9900,1277,2815,948,1605,3688,7450,51206,3685,3691,3911,3918	COL4A2,FN1,AGRN,HSPG2,ITGA6,SDC4,TNXB,GP1BB,THBS3,LAMA1,SDC1,COL6A3,LAMB3,LAMA3,ITGB8,ITGA3,VTN,COL6A1,COL2A1,COL5A1,LAMB2,ITGA11,TNN,CD44,ITGA1,ITGA10,ITGB6,COMP,HMMR,COL6A2,LAMC1,TNR,THBS2,SV2A,COL1A1,GP9,CD36,DAG1,ITGB1,VWF,GP6,ITGAV,ITGB4,LAMA5,LAMC2
M00388	ECS complex	0.113612183838439	-2.17496452634724	12	8	0.00263852242744063	3032	6715	1154,6923,8651,9616,8835,9306,6921,9021	CISH,TCEB2,SOCS1,RNF7,SOCS2,SOCS6,TCEB1,SOCS3
ko00740	Riboflavin metabolism	0.113612183838439	-2.17496452634724	12	8	0.00263852242744063	3032	6715	80308,5167,55312,51205,645,7299,52,55	FLAD1,ENPP1,RFK,ACP6,BLVRB,TYR,ACP1,ACPP
hsa00740	Riboflavin metabolism	0.113612183838439	-2.17496452634724	12	8	0.00263852242744063	3032	6715	80308,5167,55312,51205,645,52,7299,55	FLAD1,ENPP1,RFK,ACP6,BLVRB,ACP1,TYR,ACPP
M00004	Pentose phosphate pathway (Pentose phosphate cycle)	0.113612183838439	-2.17496452634724	12	8	0.00263852242744063	3032	6715	25796,7086,2821,6888,6120,9563,5226,22934	PGLS,TKT,GPI,TALDO1,RPE,H6PD,PGD,RPIA
hsa_M00388	ECS complex	0.113612183838439	-2.17496452634724	12	8	0.00263852242744063	3032	6715	1154,6923,8651,9616,8835,9306,6921,9021	CISH,TCEB2,SOCS1,RNF7,SOCS2,SOCS6,TCEB1,SOCS3
hsa_M00004	Pentose phosphate pathway (Pentose phosphate cycle)	0.113612183838439	-2.17496452634724	12	8	0.00263852242744063	3032	6715	25796,7086,2821,6888,6120,9563,5226,22934	PGLS,TKT,GPI,TALDO1,RPE,H6PD,PGD,RPIA
hsa04976	Bile secretion	0.117584695753215	-2.14059639013925	72	38	0.012532981530343	3032	6715	7363,6513,6256,3949,6344,358,6522,366,6523,5566,57835,3781,112,6548,109,57552,477,5567,343,2052,3156,113,200931,10257,9971,480,107,5613,1244,481,476,486,111,114,6550,8714,949,478	UGT2B4,SLC2A1,RXRA,LDLR,SCTR,AQP1,SLC4A2,AQP9,SLC5A1,PRKACA,SLC4A5,KCNN2,ADCY6,SLC9A1,ADCY3,NCEH1,ATP1A2,PRKACB,AQP8,EPHX1,HMGCR,ADCY7,SLC51A,ABCC4,NR1H4,ATP1A4,ADCY1,PRKX,ABCC2,ATP1B1,ATP1A1,FXYD2,ADCY5,ADCY8,SLC9A3,ABCC3,SCARB1,ATP1A3
ko04976	Bile secretion	0.117584695753215	-2.14059639013925	72	38	0.012532981530343	3032	6715	7363,6513,6256,3949,6344,358,6522,366,6523,5566,57835,3781,112,6548,109,57552,477,5567,343,2052,3156,113,200931,10257,9971,480,107,5613,1244,481,476,486,111,114,6550,8714,949,478	UGT2B4,SLC2A1,RXRA,LDLR,SCTR,AQP1,SLC4A2,AQP9,SLC5A1,PRKACA,SLC4A5,KCNN2,ADCY6,SLC9A1,ADCY3,NCEH1,ATP1A2,PRKACB,AQP8,EPHX1,HMGCR,ADCY7,SLC51A,ABCC4,NR1H4,ATP1A4,ADCY1,PRKX,ABCC2,ATP1B1,ATP1A1,FXYD2,ADCY5,ADCY8,SLC9A3,ABCC3,SCARB1,ATP1A3
hsa05202	Transcriptional misregulation in cancer	0.121395789659639	-2.10869908250973	179	89	0.029353562005277	3032	6715	126961,2005,4149,942,6256,5087,8358,1026,8938,25942,8290,4353,5218,8864,5154,6760,79058,2209,4790,51274,6935,9915,4233,2115,4094,6688,3486,3562,7709,5914,330,7704,4914,3021,929,84444,3087,7185,904,2321,3576,3248,861,2521,3020,30012,3066,4208,4318,8091,860,55204,3728,1236,6929,2119,5090,3398,5081,7048,4609,653604,2313,4299,5079,85414,6667,6258,221037,8861,4298,5747,1437,3560,4221,6692,4804,8148,1051,8842,7849,1025,4066,472,5546,1655,1649,333932,1436	HIST2H3C,ELK4,MAX,CD86,RXRA,PBX1,HIST1H3B,CDKN1A,BAIAP3,SIN3A,HIST3H3,MPO,CDK14,PER2,PDGFA,SS18,ASPSCR1,FCGR1A,NFKB1,KLF3,ZEB1,ARNT2,MET,ETV1,MAF,SPI1,IGFBP3,IL3,ZBTB17,RARA,BIRC3,ZBTB16,NTRK1,H3F3B,CD14,DOT1L,HHEX,TRAF1,CCNT1,FLT1,IL8,HPGD,RUNX1,FUS,H3F3A,TLX3,HDAC2,MEF2C,MMP9,HMGA2,RUNX2,GOLPH3L,JUP,CCR7,TCF3,ETV5,PBX3,ID2,PAX7,TGFBR2,MYC,HIST2H3D,FLI1,AFF1,PAX5,SLC45A3,SP1,RXRG,JMJD1C,LDB1,MLLT1,PTK2,CSF2,IL2RB,MEN1,SPINT1,NGFR,TAF15,CEBPB,PROM1,PAX8,CDK9,LYL1,ATM,PRCC,DDX5,DDIT3,HIST2H3A,CSF1R
ko05202	Transcriptional misregulation in cancer	0.121395789659639	-2.10869908250973	179	89	0.029353562005277	3032	6715	126961,2005,4149,942,6256,5087,8358,1026,8938,25942,8290,4353,5218,8864,5154,6760,79058,2209,4790,51274,6935,9915,4233,2115,4094,6688,3486,3562,7709,5914,330,7704,4914,3021,929,84444,3087,7185,904,2321,3576,3248,861,2521,3020,30012,3066,4208,4318,8091,860,55204,3728,1236,6929,2119,5090,3398,5081,7048,4609,653604,2313,4299,5079,85414,6667,6258,221037,8861,4298,5747,1437,3560,4221,6692,4804,8148,1051,8842,7849,1025,4066,472,5546,1655,1649,333932,1436	HIST2H3C,ELK4,MAX,CD86,RXRA,PBX1,HIST1H3B,CDKN1A,BAIAP3,SIN3A,HIST3H3,MPO,CDK14,PER2,PDGFA,SS18,ASPSCR1,FCGR1A,NFKB1,KLF3,ZEB1,ARNT2,MET,ETV1,MAF,SPI1,IGFBP3,IL3,ZBTB17,RARA,BIRC3,ZBTB16,NTRK1,H3F3B,CD14,DOT1L,HHEX,TRAF1,CCNT1,FLT1,IL8,HPGD,RUNX1,FUS,H3F3A,TLX3,HDAC2,MEF2C,MMP9,HMGA2,RUNX2,GOLPH3L,JUP,CCR7,TCF3,ETV5,PBX3,ID2,PAX7,TGFBR2,MYC,HIST2H3D,FLI1,AFF1,PAX5,SLC45A3,SP1,RXRG,JMJD1C,LDB1,MLLT1,PTK2,CSF2,IL2RB,MEN1,SPINT1,NGFR,TAF15,CEBPB,PROM1,PAX8,CDK9,LYL1,ATM,PRCC,DDX5,DDIT3,HIST2H3A,CSF1R
ko05212	Pancreatic cancer	0.121562779319137	-2.10732444743104	66	35	0.0115435356200528	3032	6715	5894,10928,2064,5900,7046,7042,7048,5881,595,5880,23533,5899,3551,4790,5296,5601,5290,8503,6774,207,7039,1019,5295,1871,3845,7422,1956,5898,4088,8517,4087,10000,5337,1870,4089	RAF1,RALBP1,ERBB2,RALGDS,TGFBR1,TGFB2,TGFBR2,RAC3,CCND1,RAC2,PIK3R5,RALB,IKBKB,NFKB1,PIK3R2,MAPK9,PIK3CA,PIK3R3,STAT3,AKT1,TGFA,CDK4,PIK3R1,E2F3,KRAS,VEGFA,EGFR,RALA,SMAD3,IKBKG,SMAD2,AKT3,PLD1,E2F2,SMAD4
hsa05212	Pancreatic cancer	0.121562779319137	-2.10732444743104	66	35	0.0115435356200528	3032	6715	5894,10928,2064,5900,7046,7042,7048,5881,595,5880,23533,5899,3551,4790,5296,5601,5290,8503,6774,207,7039,1019,5295,1871,3845,7422,1956,5898,4088,8517,4087,10000,5337,1870,4089	RAF1,RALBP1,ERBB2,RALGDS,TGFBR1,TGFB2,TGFBR2,RAC3,CCND1,RAC2,PIK3R5,RALB,IKBKB,NFKB1,PIK3R2,MAPK9,PIK3CA,PIK3R3,STAT3,AKT1,TGFA,CDK4,PIK3R1,E2F3,KRAS,VEGFA,EGFR,RALA,SMAD3,IKBKG,SMAD2,AKT3,PLD1,E2F2,SMAD4
M00383	ECV complex	0.132665926087408	-2.01992114463711	5	4	0.00131926121372032	3032	6715	6921,6923,9978,8453	TCEB1,TCEB2,RBX1,CUL2
M00380	SCF-BTRC complex	0.132665926087408	-2.01992114463711	5	4	0.00131926121372032	3032	6715	6500,23291,9978,8945	SKP1,FBXW11,RBX1,BTRC
hsa_M00380	SCF-BTRC complex	0.132665926087408	-2.01992114463711	5	4	0.00131926121372032	3032	6715	6500,23291,9978,8945	SKP1,FBXW11,RBX1,BTRC
hsa_M00383	ECV complex	0.132665926087408	-2.01992114463711	5	4	0.00131926121372032	3032	6715	6921,6923,9978,8453	TCEB1,TCEB2,RBX1,CUL2
ko04961	Endocrine and other factor-regulated calcium reabsorption	0.132801778812498	-2.01889764735709	48	26	0.00857519788918206	3032	6715	26052,5745,480,793,5613,481,5578,5566,8766,3817,5331,7421,161,476,486,56302,160,1785,112,5332,1211,1212,5330,477,5567,478	DNM3,PTH1R,ATP1A4,CALB1,PRKX,ATP1B1,PRKCA,PRKACA,RAB11A,KLK2,PLCB3,VDR,AP2A2,ATP1A1,FXYD2,TRPV5,AP2A1,DNM2,ADCY6,PLCB4,CLTA,CLTB,PLCB2,ATP1A2,PRKACB,ATP1A3
hsa04961	Endocrine and other factor-regulated calcium reabsorption	0.132801778812498	-2.01889764735709	48	26	0.00857519788918206	3032	6715	26052,5745,480,793,5613,481,5578,5566,8766,3817,5331,7421,161,476,486,56302,160,1785,112,5332,1211,1212,5330,477,5567,478	DNM3,PTH1R,ATP1A4,CALB1,PRKX,ATP1B1,PRKCA,PRKACA,RAB11A,KLK2,PLCB3,VDR,AP2A2,ATP1A1,FXYD2,TRPV5,AP2A1,DNM2,ADCY6,PLCB4,CLTA,CLTB,PLCB2,ATP1A2,PRKACB,ATP1A3
M00359	Aminoacyl-tRNA biosynthesis, eukaryotes	0.137427398704579	-1.98465951074282	38	21	0.00692612137203166	3032	6715	79731,833,51520,10352,4677,57505,10667,7407,80222,6897,51067,54938,2058,5917,1615,55157,55699,23438,10056,123283,79587	NARS2,CARS,LARS,WARS2,NARS,AARS2,FARS2,VARS,TARS2,TARS,YARS2,SARS2,EPRS,RARS,DARS,DARS2,IARS2,HARS2,FARSB,TARSL2,CARS2
hsa_M00359	Aminoacyl-tRNA biosynthesis, eukaryotes	0.137427398704579	-1.98465951074282	38	21	0.00692612137203166	3032	6715	79731,833,51520,10352,4677,57505,10667,7407,80222,6897,51067,54938,2058,5917,1615,55157,55699,23438,10056,123283,79587	NARS2,CARS,LARS,WARS2,NARS,AARS2,FARS2,VARS,TARS2,TARS,YARS2,SARS2,EPRS,RARS,DARS,DARS2,IARS2,HARS2,FARSB,TARSL2,CARS2
hsa00340	Histidine metabolism	0.138574171774026	-1.97634956042856	28	16	0.00527704485488127	3032	6715	51409,131669,84735,57571,219,222,10841,221,220,218,4128,501,55748,55798,224,1644	HEMK1,UROC1,CNDP1,CARNS1,ALDH1B1,ALDH3B2,FTCD,ALDH3B1,ALDH1A3,ALDH3A1,MAOA,ALDH7A1,CNDP2,METTL2B,ALDH3A2,DDC
ko00760	Nicotinate and nicotinamide metabolism	0.138574171774026	-1.97634956042856	28	16	0.00527704485488127	3032	6715	55191,349565,4837,4860,64802,952,51251,83594,93100,10135,5167,23057,30833,56953,65220,4907	NADSYN1,NMNAT3,NNMT,PNP,NMNAT1,CD38,NT5C3A,NUDT12,NAPRT1,NAMPT,ENPP1,NMNAT2,NT5C,NT5M,NADK,NT5E
hsa00760	Nicotinate and nicotinamide metabolism	0.138574171774026	-1.97634956042856	28	16	0.00527704485488127	3032	6715	55191,349565,4837,64802,4860,952,51251,93100,83594,10135,5167,23057,30833,56953,65220,4907	NADSYN1,NMNAT3,NNMT,NMNAT1,PNP,CD38,NT5C3A,NAPRT1,NUDT12,NAMPT,ENPP1,NMNAT2,NT5C,NT5M,NADK,NT5E
ko00340	Histidine metabolism	0.138574171774026	-1.97634956042856	28	16	0.00527704485488127	3032	6715	51409,131669,84735,57571,219,222,10841,221,220,218,4128,501,55748,224,55798,1644	HEMK1,UROC1,CNDP1,CARNS1,ALDH1B1,ALDH3B2,FTCD,ALDH3B1,ALDH1A3,ALDH3A1,MAOA,ALDH7A1,CNDP2,ALDH3A2,METTL2B,DDC
hsa05134	Legionellosis	0.159272001903065	-1.83714183455612	55	29	0.0095646437994723	3032	6715	718,1195,3312,3297,3606,54205,375,929,23786,5861,3303,1915,7415,3304,3310,51128,3689,56681,1378,4792,3576,81876,4790,9554,664,317,4791,3306,7100	C3,CLK1,HSPA8,HSF1,IL18,CYCS,ARF1,CD14,BCL2L13,RAB1A,HSPA1A,EEF1A1,VCP,HSPA1B,HSPA6,SAR1B,ITGB2,SAR1A,CR1,NFKBIA,IL8,RAB1B,NFKB1,SEC22B,BNIP3,APAF1,NFKB2,HSPA2,TLR5
ko05134	Legionellosis	0.159272001903065	-1.83714183455612	55	29	0.0095646437994723	3032	6715	718,1195,3312,3297,3606,54205,375,929,23786,5861,3303,1915,7415,3304,3310,51128,3689,56681,1378,4792,3576,81876,4790,9554,664,317,4791,3306,7100	C3,CLK1,HSPA8,HSF1,IL18,CYCS,ARF1,CD14,BCL2L13,RAB1A,HSPA1A,EEF1A1,VCP,HSPA1B,HSPA6,SAR1B,ITGB2,SAR1A,CR1,NFKBIA,IL8,RAB1B,NFKB1,SEC22B,BNIP3,APAF1,NFKB2,HSPA2,TLR5
ko04670	Leukocyte transendothelial migration	0.164946828713071	-1.80213210723913	118	59	0.0194591029023747	3032	6715	4318,7122,71,1495,7410,50848,88,5578,1432,23562,4688,3383,7409,5880,1499,23533,5336,653361,5296,4313,5781,5290,8503,1364,5600,10411,1365,7414,2771,4636,1366,10451,5829,4689,9080,11069,5295,83593,93408,87,5747,9074,9564,10627,83700,3689,7070,5335,1003,3688,81,2185,60,6093,4478,103910,9071,149461,6300	MMP9,CLDN5,ACTG1,CTNNA1,VAV2,F11R,ACTN2,PRKCA,MAPK14,CLDN14,NCF2,ICAM1,VAV1,RAC2,CTNNB1,PIK3R5,PLCG2,NCF1,PIK3R2,MMP2,PTPN11,PIK3CA,PIK3R3,CLDN4,MAPK11,RAPGEF3,CLDN3,VCL,GNAI2,MYL5,CLDN7,VAV3,PXN,NCF4,CLDN9,RAPGEF4,PIK3R1,RASSF5,MYL10,ACTN1,PTK2,CLDN6,BCAR1,MYL12A,JAM3,ITGB2,THY1,PLCG1,CDH5,ITGB1,ACTN4,PTK2B,ACTB,ROCK1,MSN,MYL12B,CLDN10,CLDN19,MAPK12
hsa04670	Leukocyte transendothelial migration	0.164946828713071	-1.80213210723913	118	59	0.0194591029023747	3032	6715	4318,7122,71,1495,7410,50848,88,5578,1432,23562,4688,3383,7409,5880,1499,23533,5336,653361,5296,4313,5781,5290,8503,1364,5600,10411,1365,7414,2771,4636,1366,10451,5829,4689,9080,11069,5295,83593,93408,87,5747,9074,9564,10627,83700,3689,7070,5335,1003,3688,81,2185,60,6093,4478,103910,9071,149461,6300	MMP9,CLDN5,ACTG1,CTNNA1,VAV2,F11R,ACTN2,PRKCA,MAPK14,CLDN14,NCF2,ICAM1,VAV1,RAC2,CTNNB1,PIK3R5,PLCG2,NCF1,PIK3R2,MMP2,PTPN11,PIK3CA,PIK3R3,CLDN4,MAPK11,RAPGEF3,CLDN3,VCL,GNAI2,MYL5,CLDN7,VAV3,PXN,NCF4,CLDN9,RAPGEF4,PIK3R1,RASSF5,MYL10,ACTN1,PTK2,CLDN6,BCAR1,MYL12A,JAM3,ITGB2,THY1,PLCG1,CDH5,ITGB1,ACTN4,PTK2B,ACTB,ROCK1,MSN,MYL12B,CLDN10,CLDN19,MAPK12
M00076	Dermatan sulfate degradation	0.16803274266478	-1.78359642175463	9	6	0.00197889182058048	3032	6715	3423,3373,8372,411,3425,8692	IDS,HYAL1,HYAL3,ARSB,IDUA,HYAL2
hsa_M00076	Dermatan sulfate degradation	0.16803274266478	-1.78359642175463	9	6	0.00197889182058048	3032	6715	3423,3373,8372,411,3425,8692	IDS,HYAL1,HYAL3,ARSB,IDUA,HYAL2
M00078	Heparan sulfate degradation	0.16803274266478	-1.78359642175463	9	6	0.00197889182058048	3032	6715	3423,6448,10855,138050,3425,4669	IDS,SGSH,HPSE,HGSNAT,IDUA,NAGLU
hsa_M00078	Heparan sulfate degradation	0.16803274266478	-1.78359642175463	9	6	0.00197889182058048	3032	6715	3423,6448,10855,138050,3425,4669	IDS,SGSH,HPSE,HGSNAT,IDUA,NAGLU
ko00620	Pyruvate metabolism	0.173412134990829	-1.75208423443829	41	22	0.00725593667546174	3032	6715	5160,5313,3939,57016,5161,2739,219,5315,3029,197257,92483,9380,5091,55902,84264,5105,98,501,4200,84532,224,3945	PDHA1,PKLR,LDHA,AKR1B10,PDHA2,GLO1,ALDH1B1,PKM,HAGH,LDHD,LDHAL6B,GRHPR,PC,ACSS2,HAGHL,PCK1,ACYP2,ALDH7A1,ME2,ACSS1,ALDH3A2,LDHB
hsa00620	Pyruvate metabolism	0.173412134990829	-1.75208423443829	41	22	0.00725593667546174	3032	6715	5160,5313,57016,3939,5161,2739,219,5315,3029,197257,92483,9380,5091,55902,84264,5105,501,98,4200,84532,224,3945	PDHA1,PKLR,AKR1B10,LDHA,PDHA2,GLO1,ALDH1B1,PKM,HAGH,LDHD,LDHAL6B,GRHPR,PC,ACSS2,HAGHL,PCK1,ALDH7A1,ACYP2,ME2,ACSS1,ALDH3A2,LDHB
ko04920	Adipocytokine signaling pathway	0.17353561262373	-1.75137244057905	70	36	0.0118733509234828	3032	6715	5563,5564,2180,4794,2475,84254,7186,5565,6513,6256,5562,3551,4790,5601,5105,5781,3717,3952,6774,51703,6258,10645,207,2181,92579,948,8471,9021,53632,8517,51422,10000,23305,4792,7132,51094	PRKAA2,PRKAB1,ACSL1,NFKBIE,MTOR,CAMKK1,TRAF2,PRKAB2,SLC2A1,RXRA,PRKAA1,IKBKB,NFKB1,MAPK9,PCK1,PTPN11,JAK2,LEP,STAT3,ACSL5,RXRG,CAMKK2,AKT1,ACSL3,G6PC3,CD36,IRS4,SOCS3,PRKAG3,IKBKG,PRKAG2,AKT3,ACSL6,NFKBIA,TNFRSF1A,ADIPOR1
hsa04920	Adipocytokine signaling pathway	0.17353561262373	-1.75137244057905	70	36	0.0118733509234828	3032	6715	5563,5564,2180,4794,2475,84254,7186,5565,6513,6256,5562,3551,4790,5601,5105,5781,3717,3952,6774,51703,6258,10645,207,2181,92579,948,8471,9021,53632,8517,51422,10000,23305,4792,7132,51094	PRKAA2,PRKAB1,ACSL1,NFKBIE,MTOR,CAMKK1,TRAF2,PRKAB2,SLC2A1,RXRA,PRKAA1,IKBKB,NFKB1,MAPK9,PCK1,PTPN11,JAK2,LEP,STAT3,ACSL5,RXRG,CAMKK2,AKT1,ACSL3,G6PC3,CD36,IRS4,SOCS3,PRKAG3,IKBKG,PRKAG2,AKT3,ACSL6,NFKBIA,TNFRSF1A,ADIPOR1
hsa05161	Hepatitis B	0.17411861663182	-1.74801850724219	146	72	0.0237467018469657	3032	6715	9134,64764,3339,5894,537,3661,1026,1960,5578,898,595,5111,3551,4790,5296,5290,8503,7419,57506,1386,468,207,1019,1871,10971,90993,4773,4772,1959,4088,8517,6778,3576,2185,3665,1870,4089,4318,1388,54205,7046,9586,7042,6714,3725,4775,23533,4609,5601,1385,6774,1643,29110,148327,6775,5295,3845,3454,2353,5605,8772,355,9641,10000,4792,356,6776,7534,4776,317,3265,1642	CCNE2,CREB3L2,HSPG2,RAF1,ATP6AP1,IRF3,CDKN1A,EGR3,PRKCA,CCNE1,CCND1,PCNA,IKBKB,NFKB1,PIK3R2,PIK3CA,PIK3R3,VDAC3,MAVS,ATF2,ATF4,AKT1,CDK4,E2F3,YWHAQ,CREB3L1,NFATC2,NFATC1,EGR2,SMAD3,IKBKG,STAT6,IL8,PTK2B,IRF7,E2F2,SMAD4,MMP9,ATF6B,CYCS,TGFBR1,CREB5,TGFB2,SRC,JUN,NFATC3,PIK3R5,MYC,MAPK9,CREB1,STAT3,DDB2,TBK1,CREB3L4,STAT4,PIK3R1,KRAS,IFNAR1,FOS,MAP2K2,FADD,FAS,IKBKE,AKT3,NFKBIA,FASLG,STAT5A,YWHAZ,NFATC4,APAF1,HRAS,DDB1
hsa05031	Amphetamine addiction	0.176139918895358	-1.73647660606049	68	35	0.0115435356200528	3032	6715	64764,1388,9586,5578,5566,3725,2890,51806,2354,5499,1385,1386,116444,818,815,5567,1644,148327,468,6531,2902,5613,90993,2353,817,6804,111,816,163688,4128,5533,23237,6571,810,1812	CREB3L2,ATF6B,CREB5,PRKCA,PRKACA,JUN,GRIA1,CALML5,FOSB,PPP1CA,CREB1,ATF2,GRIN3B,CAMK2G,CAMK2A,PRKACB,DDC,CREB3L4,ATF4,SLC6A3,GRIN1,PRKX,CREB3L1,FOS,CAMK2D,STX1A,ADCY5,CAMK2B,CALML6,MAOA,PPP3CC,ARC,SLC18A2,CALML3,DRD1
ko05031	Amphetamine addiction	0.176139918895358	-1.73647660606049	68	35	0.0115435356200528	3032	6715	64764,1388,9586,5578,5566,3725,2890,51806,2354,5499,1385,1386,116444,818,815,5567,1644,148327,468,6531,2902,5613,90993,2353,817,6804,111,816,163688,4128,5533,23237,6571,810,1812	CREB3L2,ATF6B,CREB5,PRKCA,PRKACA,JUN,GRIA1,CALML5,FOSB,PPP1CA,CREB1,ATF2,GRIN3B,CAMK2G,CAMK2A,PRKACB,DDC,CREB3L4,ATF4,SLC6A3,GRIN1,PRKX,CREB3L1,FOS,CAMK2D,STX1A,ADCY5,CAMK2B,CALML6,MAOA,PPP3CC,ARC,SLC18A2,CALML3,DRD1
ko00512	Mucin type O-Glycan biosynthesis	0.182486325211957	-1.70108003911245	31	17	0.00560686015831135	3032	6715	79695,9245,64409,114805,51809,79623,56913,2590,50614,442117,55808,6483,55568,117248,374378,6482,2650	GALNT12,GCNT3,WBSCR17,GALNT13,GALNT7,GALNT14,C1GALT1,GALNT2,GALNT9,GALNTL6,ST6GALNAC1,ST3GAL2,GALNT10,GALNT15,GALNT18,ST3GAL1,GCNT1
hsa00512	Mucin type O-Glycan biosynthesis	0.182486325211957	-1.70108003911245	31	17	0.00560686015831135	3032	6715	79695,9245,64409,114805,51809,79623,56913,2590,50614,442117,6483,55808,55568,117248,374378,6482,2650	GALNT12,GCNT3,WBSCR17,GALNT13,GALNT7,GALNT14,C1GALT1,GALNT2,GALNT9,GALNTL6,ST3GAL2,ST6GALNAC1,GALNT10,GALNT15,GALNT18,ST3GAL1,GCNT1
ko05210	Colorectal cancer	0.184246701057193	-1.69147965278292	62	32	0.0105540897097625	3032	6715	5894,5900,7046,324,54205,7042,7048,5881,3725,595,5880,1499,23533,4609,5296,5601,5290,8503,207,1630,5295,6932,3845,2353,6934,4088,83439,4087,8312,10000,2932,4089	RAF1,RALGDS,TGFBR1,APC,CYCS,TGFB2,TGFBR2,RAC3,JUN,CCND1,RAC2,CTNNB1,PIK3R5,MYC,PIK3R2,MAPK9,PIK3CA,PIK3R3,AKT1,DCC,PIK3R1,TCF7,KRAS,FOS,TCF7L2,SMAD3,TCF7L1,SMAD2,AXIN1,AKT3,GSK3B,SMAD4
hsa05210	Colorectal cancer	0.184246701057193	-1.69147965278292	62	32	0.0105540897097625	3032	6715	5894,5900,7046,324,54205,7042,7048,5881,3725,595,5880,1499,23533,4609,5296,5601,5290,8503,207,1630,5295,6932,3845,2353,6934,4088,83439,4087,8312,10000,2932,4089	RAF1,RALGDS,TGFBR1,APC,CYCS,TGFB2,TGFBR2,RAC3,JUN,CCND1,RAC2,CTNNB1,PIK3R5,MYC,PIK3R2,MAPK9,PIK3CA,PIK3R3,AKT1,DCC,PIK3R1,TCF7,KRAS,FOS,TCF7L2,SMAD3,TCF7L1,SMAD2,AXIN1,AKT3,GSK3B,SMAD4
ko00533	Glycosaminoglycan biosynthesis - keratan sulfate	0.184712466342418	-1.68895489896845	15	9	0.00296833773087071	3032	6715	2683,4166,93010,6483,8534,8703,8702,6482,6487	B4GALT1,CHST6,B3GNT7,ST3GAL2,CHST1,B4GALT3,B4GALT4,ST3GAL1,ST3GAL3
hsa00533	Glycosaminoglycan biosynthesis - keratan sulfate	0.184712466342418	-1.68895489896845	15	9	0.00296833773087071	3032	6715	2683,4166,93010,6483,8534,8702,8703,6482,6487	B4GALT1,CHST6,B3GNT7,ST3GAL2,CHST1,B4GALT4,B4GALT3,ST3GAL1,ST3GAL3
hsa04270	Vascular smooth muscle contraction	0.184763981405609	-1.68867604458497	121	60	0.0197889182058048	3032	6715	3779,5321,4659,9826,552,5894,81579,136,10267,5578,5566,100137049,5331,5583,147,10268,51806,800,5580,9138,94274,54776,112,109,779,5499,5330,8398,148,5567,123745,113,91807,5739,157855,3778,107,5613,4881,23365,10335,3710,8399,5605,2767,283748,553,2768,8605,255189,111,114,2983,3708,4638,163688,4660,5332,6093,810	KCNMB1,PLA2G4A,PPP1R12A,ARHGEF11,AVPR1A,RAF1,PLA2G12A,ADORA2B,RAMP1,PRKCA,PRKACA,PLA2G4B,PLCB3,PRKCH,ADRA1B,RAMP3,CALML5,CALD1,PRKCD,ARHGEF1,PPP1R14A,PPP1R12C,ADCY6,ADCY3,CACNA1S,PPP1CA,PLCB2,PLA2G6,ADRA1A,PRKACB,PLA2G4E,ADCY7,MYLK3,PTGIR,KCNU1,KCNMA1,ADCY1,PRKX,NPR1,ARHGEF12,MRVI1,ITPR3,PLA2G10,MAP2K2,GNA11,PLA2G4D,AVPR1B,GNA12,PLA2G4C,PLA2G4F,ADCY5,ADCY8,GUCY1B3,ITPR1,MYLK,CALML6,PPP1R12B,PLCB4,ROCK1,CALML3
ko04270	Vascular smooth muscle contraction	0.184763981405609	-1.68867604458497	121	60	0.0197889182058048	3032	6715	3779,5321,4659,9826,552,5894,81579,136,10267,5578,5566,100137049,5331,5583,147,10268,51806,800,5580,9138,94274,54776,112,109,779,5499,5330,8398,148,5567,123745,113,91807,5739,157855,3778,107,5613,4881,23365,10335,3710,8399,5605,2767,283748,553,2768,8605,255189,111,114,2983,3708,4638,163688,4660,5332,6093,810	KCNMB1,PLA2G4A,PPP1R12A,ARHGEF11,AVPR1A,RAF1,PLA2G12A,ADORA2B,RAMP1,PRKCA,PRKACA,PLA2G4B,PLCB3,PRKCH,ADRA1B,RAMP3,CALML5,CALD1,PRKCD,ARHGEF1,PPP1R14A,PPP1R12C,ADCY6,ADCY3,CACNA1S,PPP1CA,PLCB2,PLA2G6,ADRA1A,PRKACB,PLA2G4E,ADCY7,MYLK3,PTGIR,KCNU1,KCNMA1,ADCY1,PRKX,NPR1,ARHGEF12,MRVI1,ITPR3,PLA2G10,MAP2K2,GNA11,PLA2G4D,AVPR1B,GNA12,PLA2G4C,PLA2G4F,ADCY5,ADCY8,GUCY1B3,ITPR1,MYLK,CALML6,PPP1R12B,PLCB4,ROCK1,CALML3
hsa04950	Maturity onset diabetes of the young	0.186392543925266	-1.67990037793162	25	14	0.00461741424802111	3032	6715	3280,3175,3087,3170,2645,3651,3174,5313,168620,3110,389692,2494,3172,3630	HES1,ONECUT1,HHEX,FOXA2,GCK,PDX1,HNF4G,PKLR,BHLHA15,MNX1,MAFA,NR5A2,HNF4A,INS
ko04950	Maturity onset diabetes of the young	0.186392543925266	-1.67990037793162	25	14	0.00461741424802111	3032	6715	3280,3175,3087,3170,2645,3651,3174,5313,168620,3110,389692,2494,3172,3630	HES1,ONECUT1,HHEX,FOXA2,GCK,PDX1,HNF4G,PKLR,BHLHA15,MNX1,MAFA,NR5A2,HNF4A,INS
hsa04964	Proximal tubule bicarbonate reclamation	0.187172658835658	-1.67572377883378	23	13	0.00428759894459103	3032	6715	476,486,2747,762,480,6550,5105,1468,358,481,10991,477,478	ATP1A1,FXYD2,GLUD2,CA4,ATP1A4,SLC9A3,PCK1,SLC25A10,AQP1,ATP1B1,SLC38A3,ATP1A2,ATP1A3
ko04964	Proximal tubule bicarbonate reclamation	0.187172658835658	-1.67572377883378	23	13	0.00428759894459103	3032	6715	476,486,2747,762,480,6550,5105,1468,358,481,10991,477,478	ATP1A1,FXYD2,GLUD2,CA4,ATP1A4,SLC9A3,PCK1,SLC25A10,AQP1,ATP1B1,SLC38A3,ATP1A2,ATP1A3
hsa05146	Amoebiasis	0.202702779438207	-1.59601451354021	109	54	0.0178100263852243	3032	6715	384,1284,2335,2769,2774,88,912,7042,5578,284217,5566,5055,3914,5331,3909,23533,1280,4790,5296,1289,5290,8503,3913,7414,5330,5567,3915,7879,1277,5295,107,5613,5868,87,4583,929,3586,5747,1437,5869,2767,9630,3689,3554,733,3576,81,5332,1992,3315,4843,3918,5878,3911	ARG2,COL4A2,FN1,GNA15,GNAL,ACTN2,CD1D,TGFB2,PRKCA,LAMA1,PRKACA,SERPINB2,LAMB3,PLCB3,LAMA3,PIK3R5,COL2A1,NFKB1,PIK3R2,COL5A1,PIK3CA,PIK3R3,LAMB2,VCL,PLCB2,PRKACB,LAMC1,RAB7A,COL1A1,PIK3R1,ADCY1,PRKX,RAB5A,ACTN1,MUC2,CD14,IL10,PTK2,CSF2,RAB5B,GNA11,GNA14,ITGB2,IL1R1,C8G,IL8,ACTN4,PLCB4,SERPINB1,HSPB1,NOS2,LAMC2,RAB5C,LAMA5
ko05146	Amoebiasis	0.202702779438207	-1.59601451354021	109	54	0.0178100263852243	3032	6715	384,1284,2335,2769,2774,88,912,7042,5578,284217,5566,5055,3914,5331,3909,23533,1280,4790,5296,1289,5290,8503,3913,7414,5330,5567,3915,7879,1277,5295,107,5613,5868,87,4583,929,3586,5747,1437,5869,2767,9630,3689,3554,733,3576,81,5332,1992,3315,4843,3918,5878,3911	ARG2,COL4A2,FN1,GNA15,GNAL,ACTN2,CD1D,TGFB2,PRKCA,LAMA1,PRKACA,SERPINB2,LAMB3,PLCB3,LAMA3,PIK3R5,COL2A1,NFKB1,PIK3R2,COL5A1,PIK3CA,PIK3R3,LAMB2,VCL,PLCB2,PRKACB,LAMC1,RAB7A,COL1A1,PIK3R1,ADCY1,PRKX,RAB5A,ACTN1,MUC2,CD14,IL10,PTK2,CSF2,RAB5B,GNA11,GNA14,ITGB2,IL1R1,C8G,IL8,ACTN4,PLCB4,SERPINB1,HSPB1,NOS2,LAMC2,RAB5C,LAMA5
M00338	Cysteine biosynthesis, homocysteine + serine => cysteine	0.20383923436078	-1.59042366268477	2	2	0.000659630606860158	3032	6715	875,1491	CBS,CTH
hsa_M00338	Cysteine biosynthesis, homocysteine + serine => cysteine	0.20383923436078	-1.59042366268477	2	2	0.000659630606860158	3032	6715	875,1491	CBS,CTH
hsa_M00294	DNA polymerase gamma complex	0.20383923436078	-1.59042366268477	2	2	0.000659630606860158	3032	6715	11232,5428	POLG2,POLG
M00294	DNA polymerase gamma complex	0.20383923436078	-1.59042366268477	2	2	0.000659630606860158	3032	6715	11232,5428	POLG2,POLG
ko00565	Ether lipid metabolism	0.214744899743998	-1.53830446813671	42	22	0.00725593667546174	3032	6715	5321,85465,8612,5338,81579,151056,8399,100137049,283748,8611,8605,5050,255189,254531,5049,5337,5168,122618,79888,56994,8398,123745	PLA2G4A,EPT1,PPAP2C,PLD2,PLA2G12A,PLB1,PLA2G10,PLA2G4B,PLA2G4D,PPAP2A,PLA2G4C,PAFAH1B3,PLA2G4F,LPCAT4,PAFAH1B2,PLD1,ENPP2,PLD4,LPCAT1,CHPT1,PLA2G6,PLA2G4E
hsa00565	Ether lipid metabolism	0.214744899743998	-1.53830446813671	42	22	0.00725593667546174	3032	6715	5321,85465,8612,5338,81579,151056,8399,100137049,283748,8611,8605,5050,255189,254531,5049,5337,122618,79888,5168,56994,8398,123745	PLA2G4A,EPT1,PPAP2C,PLD2,PLA2G12A,PLB1,PLA2G10,PLA2G4B,PLA2G4D,PPAP2A,PLA2G4C,PAFAH1B3,PLA2G4F,LPCAT4,PAFAH1B2,PLD1,PLD4,LPCAT1,ENPP2,CHPT1,PLA2G6,PLA2G4E
ko00561	Glycerolipid metabolism	0.233641811573297	-1.4539660561451	55	28	0.00923482849604222	3032	6715	8525,346606,56895,150763,57104,1609,57016,1606,8612,1056,56894,8527,9388,219,64900,3990,23175,8611,10555,9162,84649,501,154141,57678,8694,129642,224,132158	DGKZ,MOGAT3,AGPAT4,GPAT2,PNPLA2,DGKQ,AKR1B10,DGKA,PPAP2C,CEL,AGPAT3,DGKD,LIPG,ALDH1B1,LPIN3,LIPC,LPIN1,PPAP2A,AGPAT2,DGKI,DGAT2,ALDH7A1,MBOAT1,GPAM,DGAT1,MBOAT2,ALDH3A2,GLYCTK
hsa00561	Glycerolipid metabolism	0.233641811573297	-1.4539660561451	55	28	0.00923482849604222	3032	6715	8525,346606,150763,56895,57104,1609,57016,1606,8612,1056,8527,9388,56894,219,64900,3990,23175,8611,10555,9162,84649,501,154141,57678,8694,129642,224,132158	DGKZ,MOGAT3,GPAT2,AGPAT4,PNPLA2,DGKQ,AKR1B10,DGKA,PPAP2C,CEL,DGKD,LIPG,AGPAT3,ALDH1B1,LPIN3,LIPC,LPIN1,PPAP2A,AGPAT2,DGKI,DGAT2,ALDH7A1,MBOAT1,GPAM,DGAT1,MBOAT2,ALDH3A2,GLYCTK
hsa05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	0.233760795652071	-1.45345692727203	74	37	0.0122031662269129	3032	6715	3728,71,1495,3655,6444,9254,5318,88,4000,786,1499,3696,3675,2010,1829,22801,779,3672,8515,3694,10369,27092,6262,87,6932,93589,1832,1605,6934,83439,3688,81,60,784,3685,3691,1000	JUP,ACTG1,CTNNA1,ITGA6,SGCD,CACNA2D2,PKP2,ACTN2,LMNA,CACNG1,CTNNB1,ITGB8,ITGA3,EMD,DSG2,ITGA11,CACNA1S,ITGA1,ITGA10,ITGB6,CACNG2,CACNG4,RYR2,ACTN1,TCF7,CACNA2D4,DSP,DAG1,TCF7L2,TCF7L1,ITGB1,ACTN4,ACTB,CACNB3,ITGAV,ITGB4,CDH2
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	0.233760795652071	-1.45345692727203	74	37	0.0122031662269129	3032	6715	3728,71,1495,3655,6444,9254,5318,88,4000,786,1499,3696,3675,2010,1829,22801,779,3672,8515,3694,10369,27092,6262,87,6932,93589,1832,1605,6934,83439,3688,81,60,784,3685,3691,1000	JUP,ACTG1,CTNNA1,ITGA6,SGCD,CACNA2D2,PKP2,ACTN2,LMNA,CACNG1,CTNNB1,ITGB8,ITGA3,EMD,DSG2,ITGA11,CACNA1S,ITGA1,ITGA10,ITGB6,CACNG2,CACNG4,RYR2,ACTN1,TCF7,CACNA2D4,DSP,DAG1,TCF7L2,TCF7L1,ITGB1,ACTN4,ACTB,CACNB3,ITGAV,ITGB4,CDH2
ko00052	Galactose metabolism	0.235624010664827	-1.44551791955864	30	16	0.00527704485488127	3032	6715	5236,2584,2548,2645,7360,5211,3099,57016,6476,2683,80201,3098,2585,92579,3101,2582	PGM1,GALK1,GAA,GCK,UGP2,PFKL,HK2,AKR1B10,SI,B4GALT1,HKDC1,HK1,GALK2,G6PC3,HK3,GALE
ko00410	beta-Alanine metabolism	0.235624010664827	-1.44551791955864	30	16	0.00527704485488127	3032	6715	6723,4329,1807,84735,57571,219,222,221,54498,220,218,23417,26275,501,55748,224	SRM,ALDH6A1,DPYS,CNDP1,CARNS1,ALDH1B1,ALDH3B2,ALDH3B1,SMOX,ALDH1A3,ALDH3A1,MLYCD,HIBCH,ALDH7A1,CNDP2,ALDH3A2
hsa00052	Galactose metabolism	0.235624010664827	-1.44551791955864	30	16	0.00527704485488127	3032	6715	5236,2584,2548,2645,7360,5211,57016,3099,6476,2683,80201,2585,3098,92579,3101,2582	PGM1,GALK1,GAA,GCK,UGP2,PFKL,AKR1B10,HK2,SI,B4GALT1,HKDC1,GALK2,HK1,G6PC3,HK3,GALE
hsa00410	beta-Alanine metabolism	0.235624010664827	-1.44551791955864	30	16	0.00527704485488127	3032	6715	6723,4329,1807,84735,57571,219,222,221,54498,220,218,23417,26275,501,55748,224	SRM,ALDH6A1,DPYS,CNDP1,CARNS1,ALDH1B1,ALDH3B2,ALDH3B1,SMOX,ALDH1A3,ALDH3A1,MLYCD,HIBCH,ALDH7A1,CNDP2,ALDH3A2
hsa03460	Fanconi anemia pathway	0.237742894289362	-1.43656546532457	53	27	0.00890501319261214	3032	6715	3280,9894,2067,8940,2176,22909,201254,116028,79008,2072,672,641,2189,2178,2175,2188,6118,2187,29089,80198,91442,80233,11201,29935,545,7398,51455	HES1,TELO2,ERCC1,TOP3B,FANCC,FAN1,STRA13,RMI2,SLX1B,ERCC4,BRCA1,BLM,FANCG,FANCE,FANCA,FANCF,RPA2,FANCB,UBE2T,MUS81,C19orf40,C17orf70,POLI,RPA4,ATR,USP1,REV1
ko03460	Fanconi anemia pathway	0.237742894289362	-1.43656546532457	53	27	0.00890501319261214	3032	6715	3280,9894,2067,8940,2176,22909,201254,116028,79008,2072,672,641,2189,2178,2175,2188,6118,2187,29089,80198,91442,80233,11201,29935,545,7398,51455	HES1,TELO2,ERCC1,TOP3B,FANCC,FAN1,STRA13,RMI2,SLX1B,ERCC4,BRCA1,BLM,FANCG,FANCE,FANCA,FANCF,RPA2,FANCB,UBE2T,MUS81,C19orf40,C17orf70,POLI,RPA4,ATR,USP1,REV1
hsa04540	Gap junction	0.238230682411955	-1.43451582090211	89	44	0.0145118733509235	3032	6715	7280,5607,3358,10383,5894,7082,84617,5578,5566,6714,5331,5154,112,109,5593,347688,5330,2771,5159,5567,10381,113,7277,56034,107,5613,3845,112714,3710,5605,2767,983,1956,10376,7278,111,114,2983,3708,51807,5332,3265,1453,1812	TUBB2A,MAP2K5,HTR2C,TUBB4B,RAF1,TJP1,TUBB6,PRKCA,PRKACA,SRC,PLCB3,PDGFA,ADCY6,ADCY3,PRKG2,TUBB8,PLCB2,GNAI2,PDGFRB,PRKACB,TUBB3,ADCY7,TUBA4A,PDGFC,ADCY1,PRKX,KRAS,TUBA3E,ITPR3,MAP2K2,GNA11,CDK1,EGFR,TUBA1B,TUBA3C,ADCY5,ADCY8,GUCY1B3,ITPR1,TUBA8,PLCB4,HRAS,CSNK1D,DRD1
ko04540	Gap junction	0.238230682411955	-1.43451582090211	89	44	0.0145118733509235	3032	6715	7280,5607,3358,10383,5894,7082,84617,5578,5566,6714,5331,5154,112,109,5593,347688,5330,2771,5159,5567,10381,113,7277,56034,107,5613,3845,112714,3710,5605,2767,983,1956,10376,7278,111,114,2983,3708,51807,5332,3265,1453,1812	TUBB2A,MAP2K5,HTR2C,TUBB4B,RAF1,TJP1,TUBB6,PRKCA,PRKACA,SRC,PLCB3,PDGFA,ADCY6,ADCY3,PRKG2,TUBB8,PLCB2,GNAI2,PDGFRB,PRKACB,TUBB3,ADCY7,TUBA4A,PDGFC,ADCY1,PRKX,KRAS,TUBA3E,ITPR3,MAP2K2,GNA11,CDK1,EGFR,TUBA1B,TUBA3C,ADCY5,ADCY8,GUCY1B3,ITPR1,TUBA8,PLCB4,HRAS,CSNK1D,DRD1
hsa_M00262	DNA polymerase delta complex	0.243460902262131	-1.41279891501014	4	3	0.000989445910290238	3032	6715	5424,57804,5425	POLD1,POLD4,POLD2
hsa_M00006	Pentose phosphate pathway, oxidative phase, glucose 6P => ribulose 5P	0.243460902262131	-1.41279891501014	4	3	0.000989445910290238	3032	6715	25796,5226,9563	PGLS,PGD,H6PD
M00402	Translocon-associated protein (TRAP) complex	0.243460902262131	-1.41279891501014	4	3	0.000989445910290238	3032	6715	6746,6748,6745	SSR2,SSR4,SSR1
M00006	Pentose phosphate pathway, oxidative phase, glucose 6P => ribulose 5P	0.243460902262131	-1.41279891501014	4	3	0.000989445910290238	3032	6715	25796,5226,9563	PGLS,PGD,H6PD
M00401	Sec61 complex	0.243460902262131	-1.41279891501014	4	3	0.000989445910290238	3032	6715	29927,23480,55176	SEC61A1,SEC61G,SEC61A2
hsa_M00387	SCF-FBW7 complex	0.243460902262131	-1.41279891501014	4	3	0.000989445910290238	3032	6715	6500,55294,9978	SKP1,FBXW7,RBX1
hsa_M00133	Polyamine biosynthesis, arginine => agmatine => putrescine => spermidine	0.243460902262131	-1.41279891501014	4	3	0.000989445910290238	3032	6715	6723,262,113451	SRM,AMD1,ADC
M00384	Cul3-SPOP complex	0.243460902262131	-1.41279891501014	4	3	0.000989445910290238	3032	6715	339745,9978,8452	SPOPL,RBX1,CUL3
hsa_M00401	Sec61 complex	0.243460902262131	-1.41279891501014	4	3	0.000989445910290238	3032	6715	29927,23480,55176	SEC61A1,SEC61G,SEC61A2
M00387	SCF-FBW7 complex	0.243460902262131	-1.41279891501014	4	3	0.000989445910290238	3032	6715	6500,55294,9978	SKP1,FBXW7,RBX1
hsa00730	Thiamine metabolism	0.243460902262131	-1.41279891501014	4	3	0.000989445910290238	3032	6715	84284,79178,27010	NTPCR,THTPA,TPK1
M00133	Polyamine biosynthesis, arginine => agmatine => putrescine => spermidine	0.243460902262131	-1.41279891501014	4	3	0.000989445910290238	3032	6715	6723,262,113451	SRM,AMD1,ADC
M00262	DNA polymerase delta complex	0.243460902262131	-1.41279891501014	4	3	0.000989445910290238	3032	6715	5424,57804,5425	POLD1,POLD4,POLD2
hsa_M00402	Translocon-associated protein (TRAP) complex	0.243460902262131	-1.41279891501014	4	3	0.000989445910290238	3032	6715	6746,6748,6745	SSR2,SSR4,SSR1
ko00730	Thiamine metabolism	0.243460902262131	-1.41279891501014	4	3	0.000989445910290238	3032	6715	84284,79178,27010	NTPCR,THTPA,TPK1
hsa_M00384	Cul3-SPOP complex	0.243460902262131	-1.41279891501014	4	3	0.000989445910290238	3032	6715	339745,9978,8452	SPOPL,RBX1,CUL3
hsa00630	Glyoxylate and dicarboxylate metabolism	0.246436183092098	-1.40065221113905	24	13	0.00428759894459103	3032	6715	847,5096,9380,189,6470,283871,4594,48,81888,125061,2752,2653,132158	CAT,PCCB,GRHPR,AGXT,SHMT1,PGP,MUT,ACO1,HYI,AFMID,GLUL,GCSH,GLYCTK
ko00630	Glyoxylate and dicarboxylate metabolism	0.246436183092098	-1.40065221113905	24	13	0.00428759894459103	3032	6715	847,5096,9380,189,6470,283871,4594,48,81888,125061,2752,2653,132158	CAT,PCCB,GRHPR,AGXT,SHMT1,PGP,MUT,ACO1,HYI,AFMID,GLUL,GCSH,GLYCTK
ko00010	Glycolysis / Gluconeogenesis	0.250575525592824	-1.38399490452647	66	33	0.0108839050131926	3032	6715	5313,83440,222,55902,5211,220,218,5105,501,3101,2023,224,3945,5160,5236,2597,669,3939,5161,80201,219,5315,92579,92483,221,2645,5230,226,3099,5224,3098,2821,84532	PKLR,ADPGK,ALDH3B2,ACSS2,PFKL,ALDH1A3,ALDH3A1,PCK1,ALDH7A1,HK3,ENO1,ALDH3A2,LDHB,PDHA1,PGM1,GAPDH,BPGM,LDHA,PDHA2,HKDC1,ALDH1B1,PKM,G6PC3,LDHAL6B,ALDH3B1,GCK,PGK1,ALDOA,HK2,PGAM2,HK1,GPI,ACSS1
hsa00010	Glycolysis / Gluconeogenesis	0.250575525592824	-1.38399490452647	66	33	0.0108839050131926	3032	6715	5313,83440,222,5211,55902,220,218,5105,501,3101,2023,224,3945,5160,5236,2597,669,3939,5161,80201,219,5315,92579,92483,221,2645,5230,226,3099,5224,2821,3098,84532	PKLR,ADPGK,ALDH3B2,PFKL,ACSS2,ALDH1A3,ALDH3A1,PCK1,ALDH7A1,HK3,ENO1,ALDH3A2,LDHB,PDHA1,PGM1,GAPDH,BPGM,LDHA,PDHA2,HKDC1,ALDH1B1,PKM,G6PC3,LDHAL6B,ALDH3B1,GCK,PGK1,ALDOA,HK2,PGAM2,GPI,HK1,ACSS1
ko00230	Purine metabolism	0.251815010787473	-1.37906054521913	171	82	0.0270448548812665	3032	6715	5313,955,8382,5137,377841,51251,5424,5143,51728,5139,272,5136,5145,9061,109,30833,2272,5144,55821,113,5441,107,6241,4832,5167,2983,114,55718,5437,5158,1716,548644,204,5440,353,122622,100,661,2618,957,3000,10606,10846,471,8833,112,56953,57804,64425,4907,271,5236,84284,5438,2987,954,4860,5558,5471,84265,4881,5151,5138,5315,318,159,131870,5426,29922,5439,50484,111,1633,5434,3614,246721,132,55811,56985,87178,5152,5425	PKLR,ENTPD6,NME5,PDE1C,ENTPD8,NT5C3A,POLD1,PDE4C,POLR3K,PDE3A,AMPD3,PDE1A,PDE6A,PAPSS1,ADCY3,NT5C,FHIT,PDE4D,ALLC,ADCY7,POLR2L,ADCY1,RRM2,NME3,ENPP1,GUCY1B3,ADCY8,POLR3E,POLR2H,PDE6B,DGUOK,POLR2J3,AK2,POLR2K,APRT,ADSSL1,ADA,POLR3D,GART,ENTPD5,GUCY2D,PAICS,PDE10A,ATIC,GMPS,ADCY6,NT5M,POLD4,POLR1E,NT5E,AMPD2,PGM1,NTPCR,POLR2I,GUK1,ENTPD2,PNP,PRIM2,PPAT,POLR3GL,NPR1,PDE8A,PDE2A,PKM,NUDT2,ADSS,NUDT16,POLE,NME7,POLR2J,RRM2B,ADCY5,DCK,POLR2E,IMPDH1,POLR2J2,ADK,ADCY10,ADPRM,PNPT1,PDE9A,POLD2
hsa00230	Purine metabolism	0.251815010787473	-1.37906054521913	171	82	0.0270448548812665	3032	6715	955,5313,8382,5137,377841,51251,5424,5143,51728,5139,272,5136,5145,9061,109,30833,2272,5144,55821,113,5441,107,6241,4832,5167,114,2983,55718,5437,5158,1716,548644,204,5440,353,122622,100,661,2618,957,3000,471,10606,10846,8833,112,57804,56953,64425,4907,271,5236,84284,5438,954,4860,5558,2987,5471,84265,4881,5151,5138,5315,318,159,131870,5439,29922,5426,50484,111,1633,5434,3614,246721,55811,132,5152,56985,87178,5425	ENTPD6,PKLR,NME5,PDE1C,ENTPD8,NT5C3A,POLD1,PDE4C,POLR3K,PDE3A,AMPD3,PDE1A,PDE6A,PAPSS1,ADCY3,NT5C,FHIT,PDE4D,ALLC,ADCY7,POLR2L,ADCY1,RRM2,NME3,ENPP1,ADCY8,GUCY1B3,POLR3E,POLR2H,PDE6B,DGUOK,POLR2J3,AK2,POLR2K,APRT,ADSSL1,ADA,POLR3D,GART,ENTPD5,GUCY2D,ATIC,PAICS,PDE10A,GMPS,ADCY6,POLD4,NT5M,POLR1E,NT5E,AMPD2,PGM1,NTPCR,POLR2I,ENTPD2,PNP,PRIM2,GUK1,PPAT,POLR3GL,NPR1,PDE8A,PDE2A,PKM,NUDT2,ADSS,NUDT16,POLR2J,NME7,POLE,RRM2B,ADCY5,DCK,POLR2E,IMPDH1,POLR2J2,ADCY10,ADK,PDE9A,ADPRM,PNPT1,POLD2
hsa_M00285	MCM complex	0.257702432365559	-1.35594972261959	6	4	0.00131926121372032	3032	6715	4173,4171,4174,4172	MCM4,MCM2,MCM5,MCM3
hsa_M00424	Shelterin complex	0.257702432365559	-1.35594972261959	6	4	0.00131926121372032	3032	6715	54386,7013,25913,26277	TERF2IP,TERF1,POT1,TINF2
hsa00750	Vitamin B6 metabolism	0.257702432365559	-1.35594972261959	6	4	0.00131926121372032	3032	6715	55163,57026,8566,29968	PNPO,PDXP,PDXK,PSAT1
hsa_M00048	Inosine monophosphate biosynthesis, PRPP + glutamine => IMP	0.257702432365559	-1.35594972261959	6	4	0.00131926121372032	3032	6715	2618,5471,10606,471	GART,PPAT,PAICS,ATIC
hsa_M00141	C1-unit interconversion, eukaryotes	0.257702432365559	-1.35594972261959	6	4	0.00131926121372032	3032	6715	25902,6470,10797,441024	MTHFD1L,SHMT1,MTHFD2,MTHFD2L
M00141	C1-unit interconversion, eukaryotes	0.257702432365559	-1.35594972261959	6	4	0.00131926121372032	3032	6715	25902,6470,10797,441024	MTHFD1L,SHMT1,MTHFD2,MTHFD2L
M00048	Inosine monophosphate biosynthesis, PRPP + glutamine => IMP	0.257702432365559	-1.35594972261959	6	4	0.00131926121372032	3032	6715	2618,5471,10606,471	GART,PPAT,PAICS,ATIC
M00285	MCM complex	0.257702432365559	-1.35594972261959	6	4	0.00131926121372032	3032	6715	4173,4171,4174,4172	MCM4,MCM2,MCM5,MCM3
ko00750	Vitamin B6 metabolism	0.257702432365559	-1.35594972261959	6	4	0.00131926121372032	3032	6715	55163,57026,8566,29968	PNPO,PDXP,PDXK,PSAT1
M00424	Shelterin complex	0.257702432365559	-1.35594972261959	6	4	0.00131926121372032	3032	6715	54386,7013,25913,26277	TERF2IP,TERF1,POT1,TINF2
M00099	Sphingosine biosynthesis	0.259687209896482	-1.34827741105846	16	9	0.00296833773087071	3032	6715	2531,204219,8560,91012,123099,79603,10715,9517,29956	KDSR,CERS3,DEGS1,CERS5,DEGS2,CERS4,CERS1,SPTLC2,CERS2
hsa_M00099	Sphingosine biosynthesis	0.259687209896482	-1.34827741105846	16	9	0.00296833773087071	3032	6715	2531,204219,8560,91012,123099,79603,10715,9517,29956	KDSR,CERS3,DEGS1,CERS5,DEGS2,CERS4,CERS1,SPTLC2,CERS2
M00180	RNA polymerase II, eukaryotes	0.26223264872107	-1.33852319701731	14	8	0.00263852242744063	3032	6715	548644,5438,5441,5439,5440,5434,5437,246721	POLR2J3,POLR2I,POLR2L,POLR2J,POLR2K,POLR2E,POLR2H,POLR2J2
hsa_M00180	RNA polymerase II, eukaryotes	0.26223264872107	-1.33852319701731	14	8	0.00263852242744063	3032	6715	548644,5438,5441,5439,5440,5434,5437,246721	POLR2J3,POLR2I,POLR2L,POLR2J,POLR2K,POLR2E,POLR2H,POLR2J2
hsa_M00050	Guanine ribonucleotide biosynthesis IMP => GDP,GTP	0.26223264872107	-1.33852319701731	14	8	0.00263852242744063	3032	6715	2987,29922,5313,8382,8833,3614,5315,4832	GUK1,NME7,PKLR,NME5,GMPS,IMPDH1,PKM,NME3
M00050	Guanine ribonucleotide biosynthesis IMP => GDP,GTP	0.26223264872107	-1.33852319701731	14	8	0.00263852242744063	3032	6715	2987,29922,5313,8382,8833,3614,5315,4832	GUK1,NME7,PKLR,NME5,GMPS,IMPDH1,PKM,NME3
hsa_M00409	ESCRT-I complex	0.263184149123901	-1.33490130503788	8	5	0.0016490765171504	3032	6715	7251,51160,155382,55048,89853	TSG101,VPS28,VPS37D,VPS37C,MVB12B
M00409	ESCRT-I complex	0.263184149123901	-1.33490130503788	8	5	0.0016490765171504	3032	6715	7251,51160,155382,55048,89853	TSG101,VPS28,VPS37D,VPS37C,MVB12B
M00403	HRD1/SEL1 ERAD complex	0.264053513155766	-1.33160349502937	12	7	0.00230870712401055	3032	6715	79139,91319,84447,9709,7415,10956,6400	DERL1,DERL3,SYVN1,HERPUD1,VCP,OS9,SEL1L
hsa_M00403	HRD1/SEL1 ERAD complex	0.264053513155766	-1.33160349502937	12	7	0.00230870712401055	3032	6715	79139,91319,84447,9709,7415,10956,6400	DERL1,DERL3,SYVN1,HERPUD1,VCP,OS9,SEL1L
ko00920	Sulfur metabolism	0.264670446443366	-1.32926982523292	10	6	0.00197889182058048	3032	6715	54205,10380,58472,6821,54928,9061	CYCS,BPNT1,SQRDL,SUOX,IMPAD1,PAPSS1
hsa_M00035	Methionine degradation	0.264670446443366	-1.32926982523292	10	6	0.00197889182058048	3032	6715	27430,875,191,1788,10768,23382	MAT2B,CBS,AHCY,DNMT3A,AHCYL1,AHCYL2
M00035	Methionine degradation	0.264670446443366	-1.32926982523292	10	6	0.00197889182058048	3032	6715	27430,875,191,1788,10768,23382	MAT2B,CBS,AHCY,DNMT3A,AHCYL1,AHCYL2
hsa00920	Sulfur metabolism	0.264670446443366	-1.32926982523292	10	6	0.00197889182058048	3032	6715	54205,10380,58472,6821,54928,9061	CYCS,BPNT1,SQRDL,SUOX,IMPAD1,PAPSS1
hsa04974	Protein digestion and absorption	0.274854958492902	-1.29151174411453	88	43	0.0141820580474934	3032	6715	1299,10136,1284,80781,7373,5222,5645,1293,1504,169044,3783,8645,1291,1280,1357,1289,477,1298,1292,206358,1277,480,643847,1294,481,3784,1303,10008,476,486,1305,4225,5547,1306,11136,6550,643834,340024,2006,23428,1506,4311,478	COL9A3,CELA3A,COL4A2,COL18A1,COL14A1,PGA5,PRSS2,COL6A3,CTRB1,COL22A1,KCNN4,KCNK5,COL6A1,COL2A1,CPA1,COL5A1,ATP1A2,COL9A2,COL6A2,SLC36A1,COL1A1,ATP1A4,PGA4,COL7A1,ATP1B1,KCNQ1,COL12A1,KCNE3,ATP1A1,FXYD2,COL13A1,MEP1B,PRCP,COL15A1,SLC7A9,SLC9A3,PGA3,SLC6A19,ELN,SLC7A8,CTRL,MME,ATP1A3
ko04974	Protein digestion and absorption	0.274854958492902	-1.29151174411453	88	43	0.0141820580474934	3032	6715	1299,10136,1284,80781,7373,5222,5645,1293,1504,169044,3783,8645,1291,1280,1357,1289,477,1298,1292,206358,1277,480,643847,1294,481,3784,1303,10008,476,486,1305,4225,5547,1306,11136,6550,643834,340024,2006,23428,1506,4311,478	COL9A3,CELA3A,COL4A2,COL18A1,COL14A1,PGA5,PRSS2,COL6A3,CTRB1,COL22A1,KCNN4,KCNK5,COL6A1,COL2A1,CPA1,COL5A1,ATP1A2,COL9A2,COL6A2,SLC36A1,COL1A1,ATP1A4,PGA4,COL7A1,ATP1B1,KCNQ1,COL12A1,KCNE3,ATP1A1,FXYD2,COL13A1,MEP1B,PRCP,COL15A1,SLC7A9,SLC9A3,PGA3,SLC6A19,ELN,SLC7A8,CTRL,MME,ATP1A3
hsa04210	Apoptosis	0.279633391177245	-1.27427585094174	86	42	0.0138522427440633	3032	6715	1677,839,7186,2021,8737,54205,637,5566,329,8837,824,3654,23533,3551,4790,5296,5290,8503,9020,3556,5567,3562,207,330,5295,4914,5575,5613,8743,5577,8772,355,3554,8517,10000,4792,7132,356,472,5533,317,8793	DFFB,CASP6,TRAF2,ENDOG,RIPK1,CYCS,BID,PRKACA,BIRC2,CFLAR,CAPN2,IRAK1,PIK3R5,IKBKB,NFKB1,PIK3R2,PIK3CA,PIK3R3,MAP3K14,IL1RAP,PRKACB,IL3,AKT1,BIRC3,PIK3R1,NTRK1,PRKAR1B,PRKX,TNFSF10,PRKAR2B,FADD,FAS,IL1R1,IKBKG,AKT3,NFKBIA,TNFRSF1A,FASLG,ATM,PPP3CC,APAF1,TNFRSF10D
ko04210	Apoptosis	0.279633391177245	-1.27427585094174	86	42	0.0138522427440633	3032	6715	1677,839,7186,2021,8737,54205,637,5566,329,8837,824,3654,23533,3551,4790,5296,5290,8503,9020,3556,5567,3562,207,330,5295,4914,5575,5613,8743,5577,8772,355,3554,8517,10000,4792,7132,356,472,5533,317,8793	DFFB,CASP6,TRAF2,ENDOG,RIPK1,CYCS,BID,PRKACA,BIRC2,CFLAR,CAPN2,IRAK1,PIK3R5,IKBKB,NFKB1,PIK3R2,PIK3CA,PIK3R3,MAP3K14,IL1RAP,PRKACB,IL3,AKT1,BIRC3,PIK3R1,NTRK1,PRKAR1B,PRKX,TNFSF10,PRKAR2B,FADD,FAS,IL1R1,IKBKG,AKT3,NFKBIA,TNFRSF1A,FASLG,ATM,PPP3CC,APAF1,TNFRSF10D
ko03410	Base excision repair	0.286433703213	-1.25024817200291	33	17	0.00560686015831135	3032	6715	3146,142,4913,143,3978,3980,4350,5424,252969,8930,5111,5426,55247,27343,57804,4595,5425	HMGB1,PARP1,NTHL1,PARP4,LIG1,LIG3,MPG,POLD1,NEIL2,MBD4,PCNA,POLE,NEIL3,POLL,POLD4,MUTYH,POLD2
hsa03410	Base excision repair	0.286433703213	-1.25024817200291	33	17	0.00560686015831135	3032	6715	3146,5111,142,5426,4913,55247,143,27343,3978,3980,4350,5424,57804,4595,5425,252969,8930	HMGB1,PCNA,PARP1,POLE,NTHL1,NEIL3,PARP4,POLL,LIG1,LIG3,MPG,POLD1,POLD4,MUTYH,POLD2,NEIL2,MBD4
hsa04530	Tight junction	0.299096632447632	-1.20698857236103	134	64	0.0211081794195251	3032	6715	7122,57530,55870,154810,84552,71,4627,22808,50848,64398,5578,23562,4628,84612,1499,5518,4621,1364,2017,5521,4636,207,9080,2036,1019,93408,87,9074,10627,83700,57644,93643,5515,5590,81,60,5522,55844,103910,9071,56288,149461,1495,7082,88,6714,9414,5583,3993,3996,5580,1365,2771,22800,1366,6237,5872,3845,8189,27134,10000,9218,51776,3265	CLDN5,CGN,ASH1L,AMOTL1,PARD6G,ACTG1,MYH9,MRAS,F11R,MPP5,PRKCA,CLDN14,MYH10,PARD6B,CTNNB1,PPP2R1A,MYH3,CLDN4,CTTN,PPP2R2B,MYL5,AKT1,CLDN9,EPB41L1,CDK4,MYL10,ACTN1,CLDN6,MYL12A,JAM3,MYH7B,TJAP1,PPP2CA,PRKCZ,ACTN4,ACTB,PPP2R2C,PPP2R2D,MYL12B,CLDN10,PARD3,CLDN19,CTNNA1,TJP1,ACTN2,SRC,TJP2,PRKCH,LLGL2,LLGL1,PRKCD,CLDN3,GNAI2,RRAS2,CLDN7,RRAS,RAB13,KRAS,SYMPK,TJP3,AKT3,VAPA,ZAK,HRAS
ko04530	Tight junction	0.299096632447632	-1.20698857236103	134	64	0.0211081794195251	3032	6715	7122,57530,55870,154810,84552,71,4627,22808,50848,64398,5578,23562,4628,84612,1499,5518,4621,1364,2017,5521,4636,207,9080,2036,1019,93408,87,9074,10627,83700,57644,93643,5515,5590,81,60,5522,55844,103910,9071,56288,149461,1495,7082,88,6714,9414,5583,3993,3996,5580,1365,2771,22800,1366,6237,5872,3845,8189,27134,10000,9218,51776,3265	CLDN5,CGN,ASH1L,AMOTL1,PARD6G,ACTG1,MYH9,MRAS,F11R,MPP5,PRKCA,CLDN14,MYH10,PARD6B,CTNNB1,PPP2R1A,MYH3,CLDN4,CTTN,PPP2R2B,MYL5,AKT1,CLDN9,EPB41L1,CDK4,MYL10,ACTN1,CLDN6,MYL12A,JAM3,MYH7B,TJAP1,PPP2CA,PRKCZ,ACTN4,ACTB,PPP2R2C,PPP2R2D,MYL12B,CLDN10,PARD3,CLDN19,CTNNA1,TJP1,ACTN2,SRC,TJP2,PRKCH,LLGL2,LLGL1,PRKCD,CLDN3,GNAI2,RRAS2,CLDN7,RRAS,RAB13,KRAS,SYMPK,TJP3,AKT3,VAPA,ZAK,HRAS
M00056	O-glycan biosynthesis, mucin type core	0.304803037921444	-1.18808948828544	27	14	0.00461741424802111	3032	6715	56913,2590,50614,79695,442117,9245,64409,114805,117248,51809,55568,79623,374378,2650	C1GALT1,GALNT2,GALNT9,GALNT12,GALNTL6,GCNT3,WBSCR17,GALNT13,GALNT15,GALNT7,GALNT10,GALNT14,GALNT18,GCNT1
ko04966	Collecting duct acid secretion	0.304803037921444	-1.18808948828544	27	14	0.00461741424802111	3032	6715	10723,1188,10312,127124,6521,90423,527,495,528,9114,496,8992,525,9550	SLC12A7,CLCNKB,TCIRG1,ATP6V1G3,SLC4A1,ATP6V1E2,ATP6V0C,ATP4A,ATP6V1C1,ATP6V0D1,ATP4B,ATP6V0E1,ATP6V1B1,ATP6V1G1
hsa04966	Collecting duct acid secretion	0.304803037921444	-1.18808948828544	27	14	0.00461741424802111	3032	6715	10723,1188,10312,127124,6521,90423,527,495,528,9114,496,8992,525,9550	SLC12A7,CLCNKB,TCIRG1,ATP6V1G3,SLC4A1,ATP6V1E2,ATP6V0C,ATP4A,ATP6V1C1,ATP6V0D1,ATP4B,ATP6V0E1,ATP6V1B1,ATP6V1G1
hsa_M00056	O-glycan biosynthesis, mucin type core	0.304803037921444	-1.18808948828544	27	14	0.00461741424802111	3032	6715	56913,2590,50614,79695,442117,9245,64409,114805,117248,51809,55568,79623,374378,2650	C1GALT1,GALNT2,GALNT9,GALNT12,GALNTL6,GCNT3,WBSCR17,GALNT13,GALNT15,GALNT7,GALNT10,GALNT14,GALNT18,GCNT1
ko00592	alpha-Linolenic acid metabolism	0.311483458855311	-1.16640904375265	25	13	0.00428759894459103	3032	6715	283748,5321,9415,8605,255189,81579,30,151056,8310,8398,8399,100137049,123745	PLA2G4D,PLA2G4A,FADS2,PLA2G4C,PLA2G4F,PLA2G12A,ACAA1,PLB1,ACOX3,PLA2G6,PLA2G10,PLA2G4B,PLA2G4E
hsa00592	alpha-Linolenic acid metabolism	0.311483458855311	-1.16640904375265	25	13	0.00428759894459103	3032	6715	283748,5321,9415,8605,255189,81579,30,151056,8310,8398,8399,100137049,123745	PLA2G4D,PLA2G4A,FADS2,PLA2G4C,PLA2G4F,PLA2G12A,ACAA1,PLB1,ACOX3,PLA2G6,PLA2G10,PLA2G4B,PLA2G4E
ko05410	Hypertrophic cardiomyopathy (HCM)	0.325810933128803	-1.12143802558472	83	40	0.0131926121372032	3032	6715	5563,7134,5564,71,1636,3655,5565,5562,6444,9254,7042,4000,786,3696,3675,2010,22801,779,3672,8515,3694,10369,4634,7169,7170,27092,7171,6262,93589,1605,4607,53632,51422,3688,7139,60,784,3685,3691,7168	PRKAA2,TNNC1,PRKAB1,ACTG1,ACE,ITGA6,PRKAB2,PRKAA1,SGCD,CACNA2D2,TGFB2,LMNA,CACNG1,ITGB8,ITGA3,EMD,ITGA11,CACNA1S,ITGA1,ITGA10,ITGB6,CACNG2,MYL3,TPM2,TPM3,CACNG4,TPM4,RYR2,CACNA2D4,DAG1,MYBPC3,PRKAG3,PRKAG2,ITGB1,TNNT2,ACTB,CACNB3,ITGAV,ITGB4,TPM1
hsa05410	Hypertrophic cardiomyopathy (HCM)	0.325810933128803	-1.12143802558472	83	40	0.0131926121372032	3032	6715	5563,7134,5564,71,1636,3655,5565,5562,6444,9254,7042,4000,786,3696,3675,2010,22801,779,3672,8515,3694,10369,4634,7169,7170,27092,7171,6262,93589,1605,4607,53632,51422,3688,7139,60,784,3685,3691,7168	PRKAA2,TNNC1,PRKAB1,ACTG1,ACE,ITGA6,PRKAB2,PRKAA1,SGCD,CACNA2D2,TGFB2,LMNA,CACNG1,ITGB8,ITGA3,EMD,ITGA11,CACNA1S,ITGA1,ITGA10,ITGB6,CACNG2,MYL3,TPM2,TPM3,CACNG4,TPM4,RYR2,CACNA2D4,DAG1,MYBPC3,PRKAG3,PRKAG2,ITGB1,TNNT2,ACTB,CACNB3,ITGAV,ITGB4,TPM1
ko00260	Glycine, serine and threonine metabolism	0.329180795334172	-1.11114814926192	38	19	0.0062664907651715	3032	6715	189,6470,29968,23464,669,2593,875,275,1757,9380,10993,4128,501,5224,1610,132158,5723,1491,2731	AGXT,SHMT1,PSAT1,GCAT,BPGM,GAMT,CBS,AMT,SARDH,GRHPR,SDS,MAOA,ALDH7A1,PGAM2,DAO,GLYCTK,PSPH,CTH,GLDC
hsa00260	Glycine, serine and threonine metabolism	0.329180795334172	-1.11114814926192	38	19	0.0062664907651715	3032	6715	189,6470,29968,669,23464,2593,875,275,1757,9380,10993,4128,501,1610,5224,5723,132158,2731,1491	AGXT,SHMT1,PSAT1,BPGM,GCAT,GAMT,CBS,AMT,SARDH,GRHPR,SDS,MAOA,ALDH7A1,DAO,PGAM2,PSPH,GLYCTK,GLDC,CTH
ko05160	Hepatitis C	0.332625784873885	-1.10073719005119	133	63	0.020778364116095	3032	6715	7122,7189,7186,5894,6256,3949,9451,8737,3646,3661,1026,1432,23562,8554,5518,23533,3551,4790,5296,5601,10379,5290,8503,1364,5600,5521,57506,1365,6774,1366,5170,29110,207,9080,5295,3845,27102,3454,9074,7297,1956,9021,5515,8517,9641,10000,4792,3576,7132,2932,3665,7187,949,6041,5522,10197,975,3265,55844,9071,149461,3659,6300	CLDN5,TRAF6,TRAF2,RAF1,RXRA,LDLR,EIF2AK3,RIPK1,EIF3E,IRF3,CDKN1A,MAPK14,CLDN14,PIAS1,PPP2R1A,PIK3R5,IKBKB,NFKB1,PIK3R2,MAPK9,IRF9,PIK3CA,PIK3R3,CLDN4,MAPK11,PPP2R2B,MAVS,CLDN3,STAT3,CLDN7,PDPK1,TBK1,AKT1,CLDN9,PIK3R1,KRAS,EIF2AK1,IFNAR1,CLDN6,TYK2,EGFR,SOCS3,PPP2CA,IKBKG,IKBKE,AKT3,NFKBIA,IL8,TNFRSF1A,GSK3B,IRF7,TRAF3,SCARB1,RNASEL,PPP2R2C,PSME3,CD81,HRAS,PPP2R2D,CLDN10,CLDN19,IRF1,MAPK12
hsa05160	Hepatitis C	0.332625784873885	-1.10073719005119	133	63	0.020778364116095	3032	6715	7122,7189,7186,5894,6256,3949,9451,8737,3646,3661,1026,1432,23562,8554,5518,23533,3551,4790,5296,5601,10379,5290,8503,1364,5600,5521,57506,1365,6774,1366,5170,29110,207,9080,5295,3845,27102,3454,9074,7297,1956,9021,5515,8517,9641,10000,4792,3576,7132,2932,3665,7187,949,6041,5522,10197,975,3265,55844,9071,149461,3659,6300	CLDN5,TRAF6,TRAF2,RAF1,RXRA,LDLR,EIF2AK3,RIPK1,EIF3E,IRF3,CDKN1A,MAPK14,CLDN14,PIAS1,PPP2R1A,PIK3R5,IKBKB,NFKB1,PIK3R2,MAPK9,IRF9,PIK3CA,PIK3R3,CLDN4,MAPK11,PPP2R2B,MAVS,CLDN3,STAT3,CLDN7,PDPK1,TBK1,AKT1,CLDN9,PIK3R1,KRAS,EIF2AK1,IFNAR1,CLDN6,TYK2,EGFR,SOCS3,PPP2CA,IKBKG,IKBKE,AKT3,NFKBIA,IL8,TNFRSF1A,GSK3B,IRF7,TRAF3,SCARB1,RNASEL,PPP2R2C,PSME3,CD81,HRAS,PPP2R2D,CLDN10,CLDN19,IRF1,MAPK12
hsa00531	Glycosaminoglycan degradation	0.333680756017309	-1.09757056340041	19	10	0.00329815303430079	3032	6715	3423,6448,8372,10855,4669,3373,138050,411,3425,8692	IDS,SGSH,HYAL3,HPSE,NAGLU,HYAL1,HGSNAT,ARSB,IDUA,HYAL2
ko00531	Glycosaminoglycan degradation	0.333680756017309	-1.09757056340041	19	10	0.00329815303430079	3032	6715	3423,6448,8372,10855,4669,3373,138050,411,3425,8692	IDS,SGSH,HYAL3,HPSE,NAGLU,HYAL1,HGSNAT,ARSB,IDUA,HYAL2
ko04130	SNARE interactions in vesicular transport	0.336597474199879	-1.0888675011161	36	18	0.00593667546174142	3032	6715	2054,55850,9482,9341,10652,112755,8675,10228,662,6843,6804,10791,8773,116841,9554,51272,8676,6811	STX2,USE1,STX8,VAMP3,YKT6,STX1B,STX16,STX6,BNIP1,VAMP1,STX1A,VAMP5,SNAP23,SNAP47,SEC22B,BET1L,STX11,STX5
hsa04130	SNARE interactions in vesicular transport	0.336597474199879	-1.0888675011161	36	18	0.00593667546174142	3032	6715	2054,55850,9482,9341,10652,112755,8675,10228,662,6843,6804,10791,8773,116841,9554,51272,8676,6811	STX2,USE1,STX8,VAMP3,YKT6,STX1B,STX16,STX6,BNIP1,VAMP1,STX1A,VAMP5,SNAP23,SNAP47,SEC22B,BET1L,STX11,STX5
M00337	Immunoproteasome	0.341970284181149	-1.07303143405376	17	9	0.00296833773087071	3032	6715	5699,5689,5687,5696,5684,5692,5721,5685,5686	PSMB10,PSMB1,PSMA6,PSMB8,PSMA3,PSMB4,PSME2,PSMA4,PSMA5
hsa_M00337	Immunoproteasome	0.341970284181149	-1.07303143405376	17	9	0.00296833773087071	3032	6715	5699,5689,5687,5696,5684,5692,5721,5685,5686	PSMB10,PSMB1,PSMA6,PSMB8,PSMA3,PSMB4,PSME2,PSMA4,PSMA5
ko04970	Salivary secretion	0.344675426159846	-1.06515209851454	90	43	0.0141820580474934	3032	6715	6522,5578,5566,5331,147,51806,3783,1471,5555,112,6548,109,5593,5330,6558,477,148,5567,1131,113,492,480,3778,491,107,5613,952,154,820,481,3710,476,486,111,114,2983,3708,163688,5332,727897,810,493,478	SLC4A2,PRKCA,PRKACA,PLCB3,ADRA1B,CALML5,KCNN4,CST3,PRH2,ADCY6,SLC9A1,ADCY3,PRKG2,PLCB2,SLC12A2,ATP1A2,ADRA1A,PRKACB,CHRM3,ADCY7,ATP2B3,ATP1A4,KCNMA1,ATP2B2,ADCY1,PRKX,CD38,ADRB2,CAMP,ATP1B1,ITPR3,ATP1A1,FXYD2,ADCY5,ADCY8,GUCY1B3,ITPR1,CALML6,PLCB4,MUC5B,CALML3,ATP2B4,ATP1A3
ko05414	Dilated cardiomyopathy	0.344675426159846	-1.06515209851454	90	43	0.0141820580474934	3032	6715	7134,71,3655,6444,9254,7042,5566,4000,786,3696,3675,2010,112,109,22801,779,3672,8515,3694,5567,10369,4634,113,7169,7170,27092,7171,107,5613,6262,93589,1605,4607,5350,111,114,3688,7139,60,784,3685,3691,7168	TNNC1,ACTG1,ITGA6,SGCD,CACNA2D2,TGFB2,PRKACA,LMNA,CACNG1,ITGB8,ITGA3,EMD,ADCY6,ADCY3,ITGA11,CACNA1S,ITGA1,ITGA10,ITGB6,PRKACB,CACNG2,MYL3,ADCY7,TPM2,TPM3,CACNG4,TPM4,ADCY1,PRKX,RYR2,CACNA2D4,DAG1,MYBPC3,PLN,ADCY5,ADCY8,ITGB1,TNNT2,ACTB,CACNB3,ITGAV,ITGB4,TPM1
hsa05414	Dilated cardiomyopathy	0.344675426159846	-1.06515209851454	90	43	0.0141820580474934	3032	6715	7134,71,3655,6444,9254,7042,5566,4000,786,3696,3675,2010,112,109,22801,779,3672,8515,3694,5567,10369,4634,113,7169,7170,27092,7171,107,5613,6262,93589,1605,4607,5350,111,114,3688,7139,60,784,3685,3691,7168	TNNC1,ACTG1,ITGA6,SGCD,CACNA2D2,TGFB2,PRKACA,LMNA,CACNG1,ITGB8,ITGA3,EMD,ADCY6,ADCY3,ITGA11,CACNA1S,ITGA1,ITGA10,ITGB6,PRKACB,CACNG2,MYL3,ADCY7,TPM2,TPM3,CACNG4,TPM4,ADCY1,PRKX,RYR2,CACNA2D4,DAG1,MYBPC3,PLN,ADCY5,ADCY8,ITGB1,TNNT2,ACTB,CACNB3,ITGAV,ITGB4,TPM1
hsa04970	Salivary secretion	0.344675426159846	-1.06515209851454	90	43	0.0141820580474934	3032	6715	6522,5578,5566,5331,147,51806,3783,1471,5555,112,6548,109,5593,5330,6558,477,148,5567,1131,113,492,480,3778,491,107,5613,952,154,820,481,3710,476,486,111,114,2983,3708,163688,5332,727897,810,493,478	SLC4A2,PRKCA,PRKACA,PLCB3,ADRA1B,CALML5,KCNN4,CST3,PRH2,ADCY6,SLC9A1,ADCY3,PRKG2,PLCB2,SLC12A2,ATP1A2,ADRA1A,PRKACB,CHRM3,ADCY7,ATP2B3,ATP1A4,KCNMA1,ATP2B2,ADCY1,PRKX,CD38,ADRB2,CAMP,ATP1B1,ITPR3,ATP1A1,FXYD2,ADCY5,ADCY8,GUCY1B3,ITPR1,CALML6,PLCB4,MUC5B,CALML3,ATP2B4,ATP1A3
ko00600	Sphingolipid metabolism	0.352169522370859	-1.04364262167048	47	23	0.00758575197889182	3032	6715	2581,6609,2629,64781,8612,91012,8877,9517,4758,130367,410,2531,129807,8611,8560,204219,166929,123099,79603,55627,10715,56848,29956	GALC,SMPD1,GBA,CERK,PPAP2C,CERS5,SPHK1,SPTLC2,NEU1,SGPP2,ARSA,KDSR,NEU4,PPAP2A,DEGS1,CERS3,SGMS2,DEGS2,CERS4,SMPD4,CERS1,SPHK2,CERS2
hsa00600	Sphingolipid metabolism	0.352169522370859	-1.04364262167048	47	23	0.00758575197889182	3032	6715	2581,6609,2629,8612,91012,64781,8877,9517,4758,130367,410,129807,2531,8611,204219,8560,166929,123099,55627,79603,10715,56848,29956	GALC,SMPD1,GBA,PPAP2C,CERS5,CERK,SPHK1,SPTLC2,NEU1,SGPP2,ARSA,NEU4,KDSR,PPAP2A,CERS3,DEGS1,SGMS2,DEGS2,SMPD4,CERS4,CERS1,SPHK2,CERS2
ko04962	Vasopressin-regulated water reabsorption	0.359909298442312	-1.02190322804776	45	22	0.00725593667546174	3032	6715	64764,398,1781,148327,9230,90993,5613,360,5868,84516,9586,5869,5566,8766,1778,51164,396,109,112,1385,5878,5567	CREB3L2,ARHGDIG,DYNC1I2,CREB3L4,RAB11B,CREB3L1,PRKX,AQP3,RAB5A,DCTN5,CREB5,RAB5B,PRKACA,RAB11A,DYNC1H1,DCTN4,ARHGDIA,ADCY3,ADCY6,CREB1,RAB5C,PRKACB
hsa04962	Vasopressin-regulated water reabsorption	0.359909298442312	-1.02190322804776	45	22	0.00725593667546174	3032	6715	64764,398,1781,148327,9230,90993,5613,360,5868,84516,9586,5869,5566,8766,1778,51164,396,109,112,1385,5878,5567	CREB3L2,ARHGDIG,DYNC1I2,CREB3L4,RAB11B,CREB3L1,PRKX,AQP3,RAB5A,DCTN5,CREB5,RAB5B,PRKACA,RAB11A,DYNC1H1,DCTN4,ARHGDIA,ADCY3,ADCY6,CREB1,RAB5C,PRKACB
ko04514	Cell adhesion molecules (CAMs)	0.360054832759641	-1.02149894590924	147	69	0.0227572559366755	3032	6715	7122,920,942,50848,9378,6382,23562,3113,1013,999,923,5818,1364,6900,9080,6404,5797,4099,9074,214,83700,9379,3689,9369,3688,23114,6614,9071,149461,1002,57689,84628,9019,6403,3655,6385,6402,26047,29851,10666,4897,3383,3105,965,3123,5133,57555,3696,933,79679,3107,1365,1366,9672,22871,5792,8506,5788,925,4359,1462,1003,2734,3685,23308,947,1000,3897,940	CLDN5,CD4,CD86,F11R,NRXN1,SDC1,CLDN14,HLA-DPA1,CDH15,CDH1,CD6,PVRL1,CLDN4,CNTN2,CLDN9,SELPLG,PTPRM,MAG,CLDN6,ALCAM,JAM3,NRXN2,ITGB2,NRXN3,ITGB1,NFASC,SIGLEC1,CLDN10,CLDN19,CDH4,LRRC4C,NTNG2,MPZL1,SELP,ITGA6,SDC4,SELL,CNTNAP2,ICOS,CD226,NRCAM,ICAM1,HLA-A,CD58,HLA-DRB1,PDCD1,NLGN2,ITGB8,CD22,VTCN1,HLA-C,CLDN3,CLDN7,SDC3,NLGN1,PTPRF,CNTNAP1,PTPRC,CD8A,MPZ,VCAN,CDH5,GLG1,ITGAV,ICOSLG,CD34,CDH2,L1CAM,CD28
hsa04514	Cell adhesion molecules (CAMs)	0.360054832759641	-1.02149894590924	147	69	0.0227572559366755	3032	6715	7122,920,942,50848,9378,6382,23562,3113,1013,999,923,5818,1364,6900,9080,6404,5797,4099,9074,214,83700,9379,3689,9369,3688,23114,6614,9071,149461,1002,57689,84628,9019,6403,3655,6385,6402,26047,29851,10666,4897,3383,3105,965,3123,5133,57555,3696,933,79679,3107,1365,1366,9672,22871,5792,8506,5788,925,4359,1462,1003,2734,3685,23308,947,1000,3897,940	CLDN5,CD4,CD86,F11R,NRXN1,SDC1,CLDN14,HLA-DPA1,CDH15,CDH1,CD6,PVRL1,CLDN4,CNTN2,CLDN9,SELPLG,PTPRM,MAG,CLDN6,ALCAM,JAM3,NRXN2,ITGB2,NRXN3,ITGB1,NFASC,SIGLEC1,CLDN10,CLDN19,CDH4,LRRC4C,NTNG2,MPZL1,SELP,ITGA6,SDC4,SELL,CNTNAP2,ICOS,CD226,NRCAM,ICAM1,HLA-A,CD58,HLA-DRB1,PDCD1,NLGN2,ITGB8,CD22,VTCN1,HLA-C,CLDN3,CLDN7,SDC3,NLGN1,PTPRF,CNTNAP1,PTPRC,CD8A,MPZ,VCAN,CDH5,GLG1,ITGAV,ICOSLG,CD34,CDH2,L1CAM,CD28
ko00514	Other types of O-glycan biosynthesis	0.361214704201632	-1.01828274896106	30	15	0.00494722955145119	3032	6715	10690,8705,3955,5986,4242,2683,23127,79709,29954,8703,6487,23275,2526,27087,2529	FUT9,B3GALT4,LFNG,RFNG,MFNG,B4GALT1,COLGALT2,COLGALT1,POMT2,B4GALT3,ST3GAL3,POFUT2,FUT4,B3GAT1,FUT7
hsa00514	Other types of O-glycan biosynthesis	0.361214704201632	-1.01828274896106	30	15	0.00494722955145119	3032	6715	10690,8705,3955,5986,4242,2683,23127,79709,29954,8703,6487,23275,2526,27087,2529	FUT9,B3GALT4,LFNG,RFNG,MFNG,B4GALT1,COLGALT2,COLGALT1,POMT2,B4GALT3,ST3GAL3,POFUT2,FUT4,B3GAT1,FUT7
hsa05223	Non-small cell lung cancer	0.370354444651418	-0.993294773375957	56	27	0.00890501319261214	3032	6715	5170,6258,207,1019,5894,7039,6256,5295,1871,11186,2064,83593,3845,5578,5605,1956,595,5335,23533,10000,5336,5296,5290,8503,2272,1870,3265	PDPK1,RXRG,AKT1,CDK4,RAF1,TGFA,RXRA,PIK3R1,E2F3,RASSF1,ERBB2,RASSF5,KRAS,PRKCA,MAP2K2,EGFR,CCND1,PLCG1,PIK3R5,AKT3,PLCG2,PIK3R2,PIK3CA,PIK3R3,FHIT,E2F2,HRAS
ko05223	Non-small cell lung cancer	0.370354444651418	-0.993294773375957	56	27	0.00890501319261214	3032	6715	5170,6258,207,1019,5894,7039,6256,5295,1871,11186,2064,83593,3845,5578,5605,1956,595,5335,23533,10000,5336,5296,5290,8503,2272,1870,3265	PDPK1,RXRG,AKT1,CDK4,RAF1,TGFA,RXRA,PIK3R1,E2F3,RASSF1,ERBB2,RASSF5,KRAS,PRKCA,MAP2K2,EGFR,CCND1,PLCG1,PIK3R5,AKT3,PLCG2,PIK3R2,PIK3CA,PIK3R3,FHIT,E2F2,HRAS
ko04610	Complement and coagulation cascades	0.37066887280265	-0.992446141051721	69	33	0.0108839050131926	3032	6715	3075,729,3053,2153,713,4153,4179,714,5627,5345,623,462,722,2165,718,2147,1604,5329,2162,1380,725,733,5104,2159,5265,712,1378,1675,5624,7450,5054,2155,10747	CFH,C6,SERPIND1,F5,C1QB,MBL2,CD46,C1QC,PROS1,SERPINF2,BDKRB1,SERPINC1,C4BPA,F13B,C3,F2,CD55,PLAUR,F13A1,CR2,C4BPB,C8G,SERPINA5,F10,SERPINA1,C1QA,CR1,CFD,PROC,VWF,SERPINE1,F7,MASP2
hsa04610	Complement and coagulation cascades	0.37066887280265	-0.992446141051721	69	33	0.0108839050131926	3032	6715	3075,729,3053,2153,713,4153,4179,714,5627,5345,623,462,722,2165,718,2147,1604,5329,2162,1380,725,733,5104,2159,5265,712,1378,1675,5624,7450,5054,2155,10747	CFH,C6,SERPIND1,F5,C1QB,MBL2,CD46,C1QC,PROS1,SERPINF2,BDKRB1,SERPINC1,C4BPA,F13B,C3,F2,CD55,PLAUR,F13A1,CR2,C4BPB,C8G,SERPINA5,F10,SERPINA1,C1QA,CR1,CFD,PROC,VWF,SERPINE1,F7,MASP2
M00143	NADH dehydrogenase (ubiquinone) Fe-S protein/flavoprotein complex, mitochondria	0.370719696911236	-0.992309035866284	11	6	0.00197889182058048	3032	6715	4728,4731,4729,4720,4726,374291	NDUFS8,NDUFV3,NDUFV2,NDUFS2,NDUFS6,NDUFS7
M00101	Cholesterol biosynthesis, squalene 2,3-epoxide => cholesterol	0.370719696911236	-0.992309035866284	11	6	0.00197889182058048	3032	6715	7108,4047,51478,10826,1717,6307	TM7SF2,LSS,HSD17B7,FAXDC2,DHCR7,MSMO1
hsa_M00143	NADH dehydrogenase (ubiquinone) Fe-S protein/flavoprotein complex, mitochondria	0.370719696911236	-0.992309035866284	11	6	0.00197889182058048	3032	6715	4728,4731,4729,4720,4726,374291	NDUFS8,NDUFV3,NDUFV2,NDUFS2,NDUFS6,NDUFS7
M00404	COPII complex	0.370719696911236	-0.992309035866284	11	6	0.00197889182058048	3032	6715	10802,51128,22872,6396,56681,10483	SEC24A,SAR1B,SEC31A,SEC13,SAR1A,SEC23B
hsa_M00404	COPII complex	0.370719696911236	-0.992309035866284	11	6	0.00197889182058048	3032	6715	10802,51128,22872,6396,56681,10483	SEC24A,SAR1B,SEC31A,SEC13,SAR1A,SEC23B
hsa_M00032	Lysine degradation, lysine => saccharopine => acetoacetyl-CoA	0.370719696911236	-0.992309035866284	11	6	0.00197889182058048	3032	6715	501,4967,3033,2639,1743,55753	ALDH7A1,OGDH,HADH,GCDH,DLST,OGDHL
hsa_M00101	Cholesterol biosynthesis, squalene 2,3-epoxide => cholesterol	0.370719696911236	-0.992309035866284	11	6	0.00197889182058048	3032	6715	7108,4047,51478,10826,1717,6307	TM7SF2,LSS,HSD17B7,FAXDC2,DHCR7,MSMO1
M00032	Lysine degradation, lysine => saccharopine => acetoacetyl-CoA	0.370719696911236	-0.992309035866284	11	6	0.00197889182058048	3032	6715	501,4967,3033,2639,1743,55753	ALDH7A1,OGDH,HADH,GCDH,DLST,OGDHL
ko01200	Carbon metabolism	0.37878049944283	-0.97079839881892	104	49	0.0161609498680739	3032	6715	84706,4329,4594,6391,5313,7086,3418,6120,5211,55902,2805,26275,4200,6888,3101,2023,2731,5160,35,189,5096,2597,6470,25796,29968,55753,48,2271,5161,80201,4967,5315,1743,275,5226,6390,2645,2875,5091,10993,5230,226,3099,5224,2821,3098,84532,5723,22934	GPT2,ALDH6A1,MUT,SDHC,PKLR,TKT,IDH2,RPE,PFKL,ACSS2,GOT1,HIBCH,ME2,TALDO1,HK3,ENO1,GLDC,PDHA1,ACADS,AGXT,PCCB,GAPDH,SHMT1,PGLS,PSAT1,OGDHL,ACO1,FH,PDHA2,HKDC1,OGDH,PKM,DLST,AMT,PGD,SDHB,GCK,GPT,PC,SDS,PGK1,ALDOA,HK2,PGAM2,GPI,HK1,ACSS1,PSPH,RPIA
hsa01200	Carbon metabolism	0.37878049944283	-0.97079839881892	104	49	0.0161609498680739	3032	6715	84706,4329,4594,6391,5313,7086,3418,6120,5211,55902,2805,26275,4200,6888,3101,2023,2731,5160,35,189,5096,2597,6470,25796,29968,55753,48,2271,5161,80201,4967,5315,1743,275,5226,6390,2645,2875,5091,10993,5230,226,3099,5224,2821,3098,84532,5723,22934	GPT2,ALDH6A1,MUT,SDHC,PKLR,TKT,IDH2,RPE,PFKL,ACSS2,GOT1,HIBCH,ME2,TALDO1,HK3,ENO1,GLDC,PDHA1,ACADS,AGXT,PCCB,GAPDH,SHMT1,PGLS,PSAT1,OGDHL,ACO1,FH,PDHA2,HKDC1,OGDH,PKM,DLST,AMT,PGD,SDHB,GCK,GPT,PC,SDS,PGK1,ALDOA,HK2,PGAM2,GPI,HK1,ACSS1,PSPH,RPIA
hsa00601	Glycosphingolipid biosynthesis - lacto and neolacto series	0.380124527425899	-0.967256376192487	26	13	0.00428759894459103	3032	6715	6484,10690,8707,2523,2683,6489,8702,10402,8703,6487,2526,2529,10331	ST3GAL4,FUT9,B3GALT2,FUT1,B4GALT1,ST8SIA1,B4GALT4,ST3GAL6,B4GALT3,ST3GAL3,FUT4,FUT7,B3GNT3
ko00601	Glycosphingolipid biosynthesis - lacto and neolacto series	0.380124527425899	-0.967256376192487	26	13	0.00428759894459103	3032	6715	6484,10690,8707,2523,2683,6489,8703,8702,10402,6487,2526,2529,10331	ST3GAL4,FUT9,B3GALT2,FUT1,B4GALT1,ST8SIA1,B4GALT3,B4GALT4,ST3GAL6,ST3GAL3,FUT4,FUT7,B3GNT3
hsa04064	NF-kappa B signaling pathway	0.381294128932628	-0.964184209738792	91	43	0.0141820580474934	3032	6715	51588,7189,7186,8737,7329,4067,329,3383,8837,4055,3654,7706,3551,5336,4790,6351,5971,4791,6885,9020,6850,8792,27040,142,330,7128,115650,10892,929,29760,3554,5743,8517,5335,7185,23118,4616,3576,4792,7132,472,7187,7188	PIAS4,TRAF6,TRAF2,RIPK1,UBE2I,LYN,BIRC2,ICAM1,CFLAR,LTBR,IRAK1,TRIM25,IKBKB,PLCG2,NFKB1,CCL4,RELB,NFKB2,MAP3K7,MAP3K14,SYK,TNFRSF11A,LAT,PARP1,BIRC3,TNFAIP3,TNFRSF13C,MALT1,CD14,BLNK,IL1R1,PTGS2,IKBKG,PLCG1,TRAF1,TAB2,GADD45B,IL8,NFKBIA,TNFRSF1A,ATM,TRAF3,TRAF5
hsa_M00135	GABA biosynthesis, eukaryotes, putrescine => GABA	0.382123407191964	-0.9620116670704	9	5	0.0016490765171504	3032	6715	4128,501,219,224,6303	MAOA,ALDH7A1,ALDH1B1,ALDH3A2,SAT1
M00135	GABA biosynthesis, eukaryotes, putrescine => GABA	0.382123407191964	-0.9620116670704	9	5	0.0016490765171504	3032	6715	4128,501,219,224,6303	MAOA,ALDH7A1,ALDH1B1,ALDH3A2,SAT1
hsa05213	Endometrial cancer	0.386208729234942	-0.95137730635621	52	25	0.00824538258575198	3032	6715	5170,207,1495,5894,5295,2064,3845,6932,324,5605,1956,6934,595,83439,999,1499,23533,8312,4609,10000,5296,5290,8503,2932,3265	PDPK1,AKT1,CTNNA1,RAF1,PIK3R1,ERBB2,KRAS,TCF7,APC,MAP2K2,EGFR,TCF7L2,CCND1,TCF7L1,CDH1,CTNNB1,PIK3R5,AXIN1,MYC,AKT3,PIK3R2,PIK3CA,PIK3R3,GSK3B,HRAS
ko05213	Endometrial cancer	0.386208729234942	-0.95137730635621	52	25	0.00824538258575198	3032	6715	5170,207,1495,5894,5295,2064,3845,6932,324,5605,1956,6934,595,83439,999,1499,23533,8312,4609,10000,5296,5290,8503,2932,3265	PDPK1,AKT1,CTNNA1,RAF1,PIK3R1,ERBB2,KRAS,TCF7,APC,MAP2K2,EGFR,TCF7L2,CCND1,TCF7L1,CDH1,CTNNB1,PIK3R5,AXIN1,MYC,AKT3,PIK3R2,PIK3CA,PIK3R3,GSK3B,HRAS
hsa_M00160	V-type ATPase, eukaryotes	0.390552514925146	-0.940192837501816	24	12	0.00395778364116095	3032	6715	533,10312,127124,537,90423,527,528,51606,8992,9114,525,9550	ATP6V0B,TCIRG1,ATP6V1G3,ATP6AP1,ATP6V1E2,ATP6V0C,ATP6V1C1,ATP6V1H,ATP6V0E1,ATP6V0D1,ATP6V1B1,ATP6V1G1
ko00534	Glycosaminoglycan biosynthesis - heparan sulfate / heparin	0.390552514925146	-0.940192837501816	24	12	0.00395778364116095	3032	6715	126792,9394,8509,2134,9957,26229,2131,9953,11285,3340,9955,266722	B3GALT6,HS6ST1,NDST2,EXTL1,HS3ST1,B3GAT3,EXT1,HS3ST3B1,B4GALT7,NDST1,HS3ST3A1,HS6ST3
hsa00534	Glycosaminoglycan biosynthesis - heparan sulfate / heparin	0.390552514925146	-0.940192837501816	24	12	0.00395778364116095	3032	6715	126792,9394,8509,2134,9957,26229,9953,2131,3340,11285,9955,266722	B3GALT6,HS6ST1,NDST2,EXTL1,HS3ST1,B3GAT3,HS3ST3B1,EXT1,NDST1,B4GALT7,HS3ST3A1,HS6ST3
M00160	V-type ATPase, eukaryotes	0.390552514925146	-0.940192837501816	24	12	0.00395778364116095	3032	6715	533,10312,127124,537,90423,527,528,51606,8992,9114,525,9550	ATP6V0B,TCIRG1,ATP6V1G3,ATP6AP1,ATP6V1E2,ATP6V0C,ATP6V1C1,ATP6V1H,ATP6V0E1,ATP6V0D1,ATP6V1B1,ATP6V1G1
M00072	Oligosaccharyltransferase	0.394908984637107	-0.929099959271703	7	4	0.00131926121372032	3032	6715	6184,201595,1650,3703	RPN1,STT3B,DDOST,STT3A
hsa_M00007	Pentose phosphate pathway, non-oxidative phase, fructose 6P => ribose 5P	0.394908984637107	-0.929099959271703	7	4	0.00131926121372032	3032	6715	6120,6888,22934,7086	RPE,TALDO1,RPIA,TKT
M00092	Phosphatidylethanolamine (PE) biosynthesis, ethanolamine => PE	0.394908984637107	-0.929099959271703	7	4	0.00131926121372032	3032	6715	85465,55224,1120,55500	EPT1,ETNK2,CHKB,ETNK1
hsa_M00120	Coenzyme A biosynthesis, pantothenate => CoA	0.394908984637107	-0.929099959271703	7	4	0.00131926121372032	3032	6715	55229,79646,53354,60490	PANK4,PANK3,PANK1,PPCDC
hsa_M00047	Creatine pathway	0.394908984637107	-0.929099959271703	7	4	0.00131926121372032	3032	6715	1159,1152,2593,548596	CKMT1B,CKB,GAMT,CKMT1A
hsa_M00072	Oligosaccharyltransferase	0.394908984637107	-0.929099959271703	7	4	0.00131926121372032	3032	6715	6184,201595,1650,3703	RPN1,STT3B,DDOST,STT3A
M00007	Pentose phosphate pathway, non-oxidative phase, fructose 6P => ribose 5P	0.394908984637107	-0.929099959271703	7	4	0.00131926121372032	3032	6715	6120,6888,22934,7086	RPE,TALDO1,RPIA,TKT
M00047	Creatine pathway	0.394908984637107	-0.929099959271703	7	4	0.00131926121372032	3032	6715	1159,1152,2593,548596	CKMT1B,CKB,GAMT,CKMT1A
M00086	beta-Oxidation, acyl-CoA synthesis	0.394908984637107	-0.929099959271703	7	4	0.00131926121372032	3032	6715	51703,2180,2181,23305	ACSL5,ACSL1,ACSL3,ACSL6
M00120	Coenzyme A biosynthesis, pantothenate => CoA	0.394908984637107	-0.929099959271703	7	4	0.00131926121372032	3032	6715	55229,79646,53354,60490	PANK4,PANK3,PANK1,PPCDC
hsa_M00092	Phosphatidylethanolamine (PE) biosynthesis, ethanolamine => PE	0.394908984637107	-0.929099959271703	7	4	0.00131926121372032	3032	6715	85465,55224,1120,55500	EPT1,ETNK2,CHKB,ETNK1
hsa_M00086	beta-Oxidation, acyl-CoA synthesis	0.394908984637107	-0.929099959271703	7	4	0.00131926121372032	3032	6715	51703,2180,2181,23305	ACSL5,ACSL1,ACSL3,ACSL6
ko04145	Phagosome	0.396067285293476	-0.926171169803862	157	73	0.0240765171503958	3032	6715	3916,71,10383,537,6890,84617,821,6441,4353,4688,8411,525,3113,533,2209,9103,347688,1311,55176,9550,7277,718,4689,7879,5868,929,5869,948,78989,10376,3689,7278,10312,29927,51807,3688,60,527,949,8992,1781,9902,7280,23480,90423,7059,7037,3105,4074,3123,811,4153,1520,653361,3107,51606,9114,10381,2213,83547,7058,9341,112714,2214,8685,1778,9146,127124,2212,9554,3685,528,5878	LAMP1,ACTG1,TUBB4B,ATP6AP1,TAP1,TUBB6,CANX,SFTPD,MPO,NCF2,EEA1,ATP6V1B1,HLA-DPA1,ATP6V0B,FCGR1A,FCGR2C,TUBB8,COMP,SEC61A2,ATP6V1G1,TUBA4A,C3,NCF4,RAB7A,RAB5A,CD14,RAB5B,CD36,COLEC11,TUBA1B,ITGB2,TUBA3C,TCIRG1,SEC61A1,TUBA8,ITGB1,ACTB,ATP6V0C,SCARB1,ATP6V0E1,DYNC1I2,MRC2,TUBB2A,SEC61G,ATP6V1E2,THBS3,TFRC,HLA-A,M6PR,HLA-DRB1,CALR,MBL2,CTSS,NCF1,HLA-C,ATP6V1H,ATP6V0D1,TUBB3,FCGR2B,RILP,THBS2,VAMP3,TUBA3E,FCGR3A,MARCO,DYNC1H1,HGS,ATP6V1G3,FCGR2A,SEC22B,ITGAV,ATP6V1C1,RAB5C
hsa04145	Phagosome	0.396067285293476	-0.926171169803862	157	73	0.0240765171503958	3032	6715	3916,71,10383,537,6890,84617,821,6441,4353,4688,8411,525,3113,533,2209,9103,347688,1311,55176,9550,7277,718,4689,7879,5868,929,5869,948,78989,10376,3689,7278,10312,29927,51807,3688,60,527,949,8992,1781,9902,7280,23480,90423,7059,7037,3105,4074,3123,811,4153,1520,653361,3107,51606,9114,10381,2213,83547,7058,9341,112714,2214,8685,1778,9146,127124,2212,9554,3685,528,5878	LAMP1,ACTG1,TUBB4B,ATP6AP1,TAP1,TUBB6,CANX,SFTPD,MPO,NCF2,EEA1,ATP6V1B1,HLA-DPA1,ATP6V0B,FCGR1A,FCGR2C,TUBB8,COMP,SEC61A2,ATP6V1G1,TUBA4A,C3,NCF4,RAB7A,RAB5A,CD14,RAB5B,CD36,COLEC11,TUBA1B,ITGB2,TUBA3C,TCIRG1,SEC61A1,TUBA8,ITGB1,ACTB,ATP6V0C,SCARB1,ATP6V0E1,DYNC1I2,MRC2,TUBB2A,SEC61G,ATP6V1E2,THBS3,TFRC,HLA-A,M6PR,HLA-DRB1,CALR,MBL2,CTSS,NCF1,HLA-C,ATP6V1H,ATP6V0D1,TUBB3,FCGR2B,RILP,THBS2,VAMP3,TUBA3E,FCGR3A,MARCO,DYNC1H1,HGS,ATP6V1G3,FCGR2A,SEC22B,ITGAV,ATP6V1C1,RAB5C
hsa05145	Toxoplasmosis	0.396626543401488	-0.924760137749474	122	57	0.0187994722955145	3032	6715	7189,3655,3949,54205,7042,345611,284217,1432,329,3303,5606,3914,3123,3113,240,3909,8651,3654,23533,3551,4790,5296,5601,5290,8503,3913,3717,5600,6885,6774,3588,2771,3306,10105,5170,207,330,3915,3460,3312,5295,3586,7297,4261,3304,3310,8517,23118,10000,4792,7132,3688,4843,3918,3911,1234,6300	TRAF6,ITGA6,LDLR,CYCS,TGFB2,IRGM,LAMA1,MAPK14,BIRC2,HSPA1A,MAP2K3,LAMB3,HLA-DRB1,HLA-DPA1,ALOX5,LAMA3,SOCS1,IRAK1,PIK3R5,IKBKB,NFKB1,PIK3R2,MAPK9,PIK3CA,PIK3R3,LAMB2,JAK2,MAPK11,MAP3K7,STAT3,IL10RB,GNAI2,HSPA2,PPIF,PDPK1,AKT1,BIRC3,LAMC1,IFNGR2,HSPA8,PIK3R1,IL10,TYK2,CIITA,HSPA1B,HSPA6,IKBKG,TAB2,AKT3,NFKBIA,TNFRSF1A,ITGB1,NOS2,LAMC2,LAMA5,CCR5,MAPK12
ko05145	Toxoplasmosis	0.396626543401488	-0.924760137749474	122	57	0.0187994722955145	3032	6715	7189,3655,3949,54205,7042,345611,284217,1432,329,3303,5606,3914,3123,3113,240,3909,8651,3654,23533,3551,4790,5296,5601,5290,8503,3913,3717,5600,6885,6774,3588,2771,3306,10105,5170,207,330,3915,3460,3312,5295,3586,7297,4261,3304,3310,8517,23118,10000,4792,7132,3688,4843,3918,3911,1234,6300	TRAF6,ITGA6,LDLR,CYCS,TGFB2,IRGM,LAMA1,MAPK14,BIRC2,HSPA1A,MAP2K3,LAMB3,HLA-DRB1,HLA-DPA1,ALOX5,LAMA3,SOCS1,IRAK1,PIK3R5,IKBKB,NFKB1,PIK3R2,MAPK9,PIK3CA,PIK3R3,LAMB2,JAK2,MAPK11,MAP3K7,STAT3,IL10RB,GNAI2,HSPA2,PPIF,PDPK1,AKT1,BIRC3,LAMC1,IFNGR2,HSPA8,PIK3R1,IL10,TYK2,CIITA,HSPA1B,HSPA6,IKBKG,TAB2,AKT3,NFKBIA,TNFRSF1A,ITGB1,NOS2,LAMC2,LAMA5,CCR5,MAPK12
hsa_M00414	Bloom's syndrome complex	0.409653366529158	-0.892443924365935	5	3	0.000989445910290238	3032	6715	8940,641,116028	TOP3B,BLM,RMI2
hsa_M00385	Cul4-DDB1-DDB2 complex	0.409653366529158	-0.892443924365935	5	3	0.000989445910290238	3032	6715	1643,9978,1642	DDB2,RBX1,DDB1
M00057	Glycosaminoglycan biosynthesis, linkage tetrasaccharide	0.409653366529158	-0.892443924365935	5	3	0.000989445910290238	3032	6715	126792,11285,26229	B3GALT6,B4GALT7,B3GAT3
M00071	Glycosphingolipid biosynthesis, neolacto-series, LacCer => nLc4Cer	0.409653366529158	-0.892443924365935	5	3	0.000989445910290238	3032	6715	2683,8702,8703	B4GALT1,B4GALT4,B4GALT3
hsa_M00382	SCF-FBS complex	0.409653366529158	-0.892443924365935	5	3	0.000989445910290238	3032	6715	6500,26270,9978	SKP1,FBXO6,RBX1
M00385	Cul4-DDB1-DDB2 complex	0.409653366529158	-0.892443924365935	5	3	0.000989445910290238	3032	6715	1643,9978,1642	DDB2,RBX1,DDB1
hsa_M00071	Glycosphingolipid biosynthesis, neolacto-series, LacCer => nLc4Cer	0.409653366529158	-0.892443924365935	5	3	0.000989445910290238	3032	6715	2683,8702,8703	B4GALT1,B4GALT4,B4GALT3
M00414	Bloom's syndrome complex	0.409653366529158	-0.892443924365935	5	3	0.000989445910290238	3032	6715	8940,641,116028	TOP3B,BLM,RMI2
hsa_M00057	Glycosaminoglycan biosynthesis, linkage tetrasaccharide	0.409653366529158	-0.892443924365935	5	3	0.000989445910290238	3032	6715	126792,11285,26229	B3GALT6,B4GALT7,B3GAT3
M00382	SCF-FBS complex	0.409653366529158	-0.892443924365935	5	3	0.000989445910290238	3032	6715	6500,26270,9978	SKP1,FBXO6,RBX1
ko04932	Non-alcoholic fatty liver disease (NAFLD)	0.412713272717676	-0.885002182048533	151	70	0.0230870712401055	3032	6715	5564,4712,5313,29796,1346,5565,6256,9451,51079,637,3551,4790,5296,7385,5290,8503,4715,4731,4700,4720,468,1350,207,2931,27089,3630,9021,53632,125965,126328,3576,7132,9377,2932,51094,4713,1340,5563,4729,6391,7186,5562,4726,54205,4697,1327,1345,374291,3725,6945,4695,23533,5601,6720,4728,3952,1537,5295,3570,355,6390,51422,3643,10000,440567,9167,1351,356,4217,1649	PRKAB1,NDUFB6,PKLR,UQCR10,COX7A1,PRKAB2,RXRA,EIF2AK3,NDUFA13,BID,IKBKB,NFKB1,PIK3R2,UQCRC2,PIK3CA,PIK3R3,NDUFB9,NDUFV3,NDUFA6,NDUFS2,ATF4,COX7C,AKT1,GSK3A,UQCRQ,INS,SOCS3,PRKAG3,COX6B2,NDUFA11,IL8,TNFRSF1A,COX5A,GSK3B,ADIPOR1,NDUFB7,COX6B1,PRKAA2,NDUFV2,SDHC,TRAF2,PRKAA1,NDUFS6,CYCS,NDUFA4,COX4I1,COX6C,NDUFS7,JUN,MLX,NDUFA2,PIK3R5,MAPK9,SREBF1,NDUFS8,LEP,CYC1,PIK3R1,IL6R,FAS,SDHB,PRKAG2,INSR,AKT3,UQCRHL,COX7A2L,COX8A,FASLG,MAP3K5,DDIT3
hsa04932	Non-alcoholic fatty liver disease (NAFLD)	0.412713272717676	-0.885002182048533	151	70	0.0230870712401055	3032	6715	5564,4712,5313,29796,1346,5565,6256,9451,51079,637,3551,4790,5296,7385,5290,8503,4715,4731,4700,4720,468,1350,207,2931,27089,3630,9021,53632,125965,126328,3576,7132,9377,2932,51094,4713,1340,5563,4729,6391,7186,5562,4726,54205,4697,1327,1345,374291,3725,6945,4695,23533,5601,6720,4728,3952,1537,5295,3570,355,6390,51422,3643,10000,440567,9167,1351,356,4217,1649	PRKAB1,NDUFB6,PKLR,UQCR10,COX7A1,PRKAB2,RXRA,EIF2AK3,NDUFA13,BID,IKBKB,NFKB1,PIK3R2,UQCRC2,PIK3CA,PIK3R3,NDUFB9,NDUFV3,NDUFA6,NDUFS2,ATF4,COX7C,AKT1,GSK3A,UQCRQ,INS,SOCS3,PRKAG3,COX6B2,NDUFA11,IL8,TNFRSF1A,COX5A,GSK3B,ADIPOR1,NDUFB7,COX6B1,PRKAA2,NDUFV2,SDHC,TRAF2,PRKAA1,NDUFS6,CYCS,NDUFA4,COX4I1,COX6C,NDUFS7,JUN,MLX,NDUFA2,PIK3R5,MAPK9,SREBF1,NDUFS8,LEP,CYC1,PIK3R1,IL6R,FAS,SDHB,PRKAG2,INSR,AKT3,UQCRHL,COX7A2L,COX8A,FASLG,MAP3K5,DDIT3
hsa00240	Pyrimidine metabolism	0.413639956607458	-0.882759353569492	105	49	0.0161609498680739	3032	6715	548644,955,5440,8382,7371,83549,1723,377841,51251,5424,51728,7084,790,79077,661,1890,957,1503,30833,50808,56953,57804,64425,4907,7296,5438,1841,5558,4860,5441,54963,7378,1807,84265,6241,1635,318,4832,5439,29922,5426,50484,1633,55718,5434,5437,246721,87178,5425	POLR2J3,ENTPD6,POLR2K,NME5,UCK2,UCK1,DHODH,ENTPD8,NT5C3A,POLD1,POLR3K,TK2,CAD,DCTPP1,POLR3D,TYMP,ENTPD5,CTPS1,NT5C,AK3,NT5M,POLD4,POLR1E,NT5E,TXNRD1,POLR2I,DTYMK,PRIM2,PNP,POLR2L,UCKL1,UPP1,DPYS,POLR3GL,RRM2,DCTD,NUDT2,NME3,POLR2J,NME7,POLE,RRM2B,DCK,POLR3E,POLR2E,POLR2H,POLR2J2,PNPT1,POLD2
ko00240	Pyrimidine metabolism	0.413639956607458	-0.882759353569492	105	49	0.0161609498680739	3032	6715	548644,5440,955,8382,7371,1723,83549,377841,51251,5424,51728,7084,79077,790,661,1890,957,1503,30833,50808,56953,57804,64425,4907,7296,1841,5438,5441,5558,4860,54963,7378,1807,84265,6241,1635,318,4832,5426,29922,5439,50484,1633,55718,5434,5437,246721,87178,5425	POLR2J3,POLR2K,ENTPD6,NME5,UCK2,DHODH,UCK1,ENTPD8,NT5C3A,POLD1,POLR3K,TK2,DCTPP1,CAD,POLR3D,TYMP,ENTPD5,CTPS1,NT5C,AK3,NT5M,POLD4,POLR1E,NT5E,TXNRD1,DTYMK,POLR2I,POLR2L,PRIM2,PNP,UCKL1,UPP1,DPYS,POLR3GL,RRM2,DCTD,NUDT2,NME3,POLE,NME7,POLR2J,RRM2B,DCK,POLR3E,POLR2E,POLR2H,POLR2J2,PNPT1,POLD2
hsa00670	One carbon pool by folate	0.413939853829008	-0.882034596317333	20	10	0.00329815303430079	3032	6715	10841,2618,6470,10797,10588,471,25902,441024,4548,275	FTCD,GART,SHMT1,MTHFD2,MTHFS,ATIC,MTHFD1L,MTHFD2L,MTR,AMT
hsa_M00352	Spliceosome, U2-snRNP	0.413939853829008	-0.882034596317333	20	10	0.00329815303430079	3032	6715	6627,6632,10262,84844,6628,51639,6635,8175,83443,10992	SNRPA1,SNRPD1,SF3B4,PHF5A,SNRPB,SF3B14,SNRPE,SF3A2,SF3B5,SF3B2
M00352	Spliceosome, U2-snRNP	0.413939853829008	-0.882034596317333	20	10	0.00329815303430079	3032	6715	6627,6632,10262,84844,6628,51639,6635,8175,83443,10992	SNRPA1,SNRPD1,SF3B4,PHF5A,SNRPB,SF3B14,SNRPE,SF3A2,SF3B5,SF3B2
ko00670	One carbon pool by folate	0.413939853829008	-0.882034596317333	20	10	0.00329815303430079	3032	6715	10841,6470,2618,10797,10588,471,25902,441024,275,4548	FTCD,SHMT1,GART,MTHFD2,MTHFS,ATIC,MTHFD1L,MTHFD2L,AMT,MTR
hsa00511	Other glycan degradation	0.427246735952965	-0.850393596681003	18	9	0.00296833773087071	3032	6715	23324,129807,4123,4126,2629,4125,175,64772,4758	MAN2B2,NEU4,MAN2C1,MANBA,GBA,MAN2B1,AGA,ENGASE,NEU1
ko00511	Other glycan degradation	0.427246735952965	-0.850393596681003	18	9	0.00296833773087071	3032	6715	23324,129807,4123,4126,2629,4125,175,64772,4758	MAN2B2,NEU4,MAN2C1,MANBA,GBA,MAN2B1,AGA,ENGASE,NEU1
M00297	DNA-PK complex	0.427506715410069	-0.849785282167135	3	2	0.000659630606860158	3032	6715	5591,7520	PRKDC,XRCC5
hsa_M00408	ESCRT-0 complex	0.427506715410069	-0.849785282167135	3	2	0.000659630606860158	3032	6715	9146,10254	HGS,STAM2
hsa_M00554	Nucleotide sugar biosynthesis, galactose => UDP-galactose	0.427506715410069	-0.849785282167135	3	2	0.000659630606860158	3032	6715	2584,2585	GALK1,GALK2
hsa_M00134	Polyamine biosynthesis, arginine => ornithine => putrescine	0.427506715410069	-0.849785282167135	3	2	0.000659630606860158	3032	6715	384,4953	ARG2,ODC1
M00408	ESCRT-0 complex	0.427506715410069	-0.849785282167135	3	2	0.000659630606860158	3032	6715	9146,10254	HGS,STAM2
hsa_M00051	Uridine monophosphate biosynthesis, glutamine (+ PRPP) => UMP	0.427506715410069	-0.849785282167135	3	2	0.000659630606860158	3032	6715	790,1723	CAD,DHODH
M00100	Sphingosine degradation	0.427506715410069	-0.849785282167135	3	2	0.000659630606860158	3032	6715	8877,56848	SPHK1,SPHK2
M00554	Nucleotide sugar biosynthesis, galactose => UDP-galactose	0.427506715410069	-0.849785282167135	3	2	0.000659630606860158	3032	6715	2584,2585	GALK1,GALK2
M00051	Uridine monophosphate biosynthesis, glutamine (+ PRPP) => UMP	0.427506715410069	-0.849785282167135	3	2	0.000659630606860158	3032	6715	790,1723	CAD,DHODH
M00134	Polyamine biosynthesis, arginine => ornithine => putrescine	0.427506715410069	-0.849785282167135	3	2	0.000659630606860158	3032	6715	384,4953	ARG2,ODC1
hsa_M00100	Sphingosine degradation	0.427506715410069	-0.849785282167135	3	2	0.000659630606860158	3032	6715	8877,56848	SPHK1,SPHK2
hsa_M00297	DNA-PK complex	0.427506715410069	-0.849785282167135	3	2	0.000659630606860158	3032	6715	5591,7520	PRKDC,XRCC5
ko04744	Phototransduction	0.437534562364577	-0.826599576614317	29	14	0.00461741424802111	3032	6715	8787,51806,3000,5145,346562,163688,408,2782,2779,5158,2978,6011,810,131890	RGS9,CALML5,GUCY2D,PDE6A,GNAT3,CALML6,ARRB1,GNB1,GNAT1,PDE6B,GUCA1A,GRK1,CALML3,GRK7
hsa04744	Phototransduction	0.437534562364577	-0.826599576614317	29	14	0.00461741424802111	3032	6715	8787,51806,3000,5145,346562,163688,408,2782,2779,5158,2978,6011,810,131890	RGS9,CALML5,GUCY2D,PDE6A,GNAT3,CALML6,ARRB1,GNB1,GNAT1,PDE6B,GUCA1A,GRK1,CALML3,GRK7
hsa01230	Biosynthesis of amino acids	0.447920586938576	-0.803139323577614	73	34	0.0112137203166227	3032	6715	84706,384,5313,435,7086,445,875,3418,6120,2752,27430,95,5211,65263,501,2805,29920,6888,2023,1491,2597,6470,29968,48,5315,4548,5091,2875,5230,10993,226,5224,5723,22934	GPT2,ARG2,PKLR,ASL,TKT,ASS1,CBS,IDH2,RPE,GLUL,MAT2B,ACY1,PFKL,PYCRL,ALDH7A1,GOT1,PYCR2,TALDO1,ENO1,CTH,GAPDH,SHMT1,PSAT1,ACO1,PKM,MTR,PC,GPT,PGK1,SDS,ALDOA,PGAM2,PSPH,RPIA
ko01230	Biosynthesis of amino acids	0.447920586938576	-0.803139323577614	73	34	0.0112137203166227	3032	6715	84706,384,5313,435,7086,445,875,3418,6120,2752,27430,95,5211,65263,501,2805,29920,6888,2023,1491,2597,6470,29968,48,5315,4548,5091,2875,5230,10993,226,5224,5723,22934	GPT2,ARG2,PKLR,ASL,TKT,ASS1,CBS,IDH2,RPE,GLUL,MAT2B,ACY1,PFKL,PYCRL,ALDH7A1,GOT1,PYCR2,TALDO1,ENO1,CTH,GAPDH,SHMT1,PSAT1,ACO1,PKM,MTR,PC,GPT,PGK1,SDS,ALDOA,PGAM2,PSPH,RPIA
M00091	Phosphatidylcholine (PC) biosynthesis, PE => PC	0.451526433350999	-0.795121362210921	1	1	0.000329815303430079	3032	6715	10400	PEMT
hsa00472	D-Arginine and D-ornithine metabolism	0.451526433350999	-0.795121362210921	1	1	0.000329815303430079	3032	6715	1610	DAO
ko00472	D-Arginine and D-ornithine metabolism	0.451526433350999	-0.795121362210921	1	1	0.000329815303430079	3032	6715	1610	DAO
hsa_M00043	Thyroid hormone biosynthesis, tyrosine => triiodothyronine/thyroxine	0.451526433350999	-0.795121362210921	1	1	0.000329815303430079	3032	6715	7173	TPO
M00043	Thyroid hormone biosynthesis, tyrosine => triiodothyronine/thyroxine	0.451526433350999	-0.795121362210921	1	1	0.000329815303430079	3032	6715	7173	TPO
hsa_M00091	Phosphatidylcholine (PC) biosynthesis, PE => PC	0.451526433350999	-0.795121362210921	1	1	0.000329815303430079	3032	6715	10400	PEMT
hsa04730	Long-term depression	0.456046658028729	-0.785160154463669	60	28	0.00923482849604222	3032	6715	5321,5894,773,3845,3710,5578,4067,100137049,5605,2767,5331,283748,5515,2768,2890,8605,2781,5518,255189,2895,2983,3708,5332,5593,5330,2771,3265,123745	PLA2G4A,RAF1,CACNA1A,KRAS,ITPR3,PRKCA,LYN,PLA2G4B,MAP2K2,GNA11,PLCB3,PLA2G4D,PPP2CA,GNA12,GRIA1,PLA2G4C,GNAZ,PPP2R1A,PLA2G4F,GRID2,GUCY1B3,ITPR1,PLCB4,PRKG2,PLCB2,GNAI2,HRAS,PLA2G4E
ko04730	Long-term depression	0.456046658028729	-0.785160154463669	60	28	0.00923482849604222	3032	6715	5321,5894,773,3845,3710,5578,4067,100137049,5605,2767,5331,283748,5515,2768,2890,8605,2781,5518,255189,2895,2983,3708,5332,5593,5330,2771,3265,123745	PLA2G4A,RAF1,CACNA1A,KRAS,ITPR3,PRKCA,LYN,PLA2G4B,MAP2K2,GNA11,PLCB3,PLA2G4D,PPP2CA,GNA12,GRIA1,PLA2G4C,GNAZ,PPP2R1A,PLA2G4F,GRID2,GUCY1B3,ITPR1,PLCB4,PRKG2,PLCB2,GNAI2,HRAS,PLA2G4E
hsa05032	Morphine addiction	0.456290681852874	-0.784625212355532	93	43	0.0141820580474934	3032	6715	2869,3763,5137,2566,2565,2782,2570,2870,5578,5566,5143,2783,5139,5136,134,2793,10846,2568,112,109,51764,5144,2771,5567,113,2567,9568,2788,773,107,5613,2786,5151,5138,2554,3762,3765,111,114,59345,408,774,1812	GRK5,KCNJ6,PDE1C,GABRG2,GABRG1,GNB1,GABRR2,GRK6,PRKCA,PRKACA,PDE4C,GNB2,PDE3A,PDE1A,ADORA1,GNGT2,PDE10A,GABRP,ADCY6,ADCY3,GNG13,PDE4D,GNAI2,PRKACB,ADCY7,GABRG3,GABBR2,GNG7,CACNA1A,ADCY1,PRKX,GNG4,PDE8A,PDE2A,GABRA1,KCNJ5,KCNJ9,ADCY5,ADCY8,GNB4,ARRB1,CACNA1B,DRD1
ko05032	Morphine addiction	0.456290681852874	-0.784625212355532	93	43	0.0141820580474934	3032	6715	2869,3763,5137,2566,2565,2782,2570,2870,5578,5566,5143,2783,5139,5136,134,2793,10846,2568,112,109,51764,5144,2771,5567,113,2567,9568,2788,773,107,5613,2786,5151,5138,2554,3762,3765,111,114,59345,408,774,1812	GRK5,KCNJ6,PDE1C,GABRG2,GABRG1,GNB1,GABRR2,GRK6,PRKCA,PRKACA,PDE4C,GNB2,PDE3A,PDE1A,ADORA1,GNGT2,PDE10A,GABRP,ADCY6,ADCY3,GNG13,PDE4D,GNAI2,PRKACB,ADCY7,GABRG3,GABBR2,GNG7,CACNA1A,ADCY1,PRKX,GNG4,PDE8A,PDE2A,GABRA1,KCNJ5,KCNJ9,ADCY5,ADCY8,GNB4,ARRB1,CACNA1B,DRD1
hsa05218	Melanoma	0.456391528590353	-0.784404222537311	71	33	0.0108839050131926	3032	6715	5894,1026,5154,595,999,23533,5296,4286,5290,8503,4233,5159,56034,2254,207,2249,1019,27006,5295,1871,2257,3845,5605,2260,1956,2248,2246,10000,26281,8817,3082,1870,3265	RAF1,CDKN1A,PDGFA,CCND1,CDH1,PIK3R5,PIK3R2,MITF,PIK3CA,PIK3R3,MET,PDGFRB,PDGFC,FGF9,AKT1,FGF4,CDK4,FGF22,PIK3R1,E2F3,FGF12,KRAS,MAP2K2,FGFR1,EGFR,FGF3,FGF1,AKT3,FGF20,FGF18,HGF,E2F2,HRAS
ko05218	Melanoma	0.456391528590353	-0.784404222537311	71	33	0.0108839050131926	3032	6715	5894,1026,5154,595,999,23533,5296,4286,5290,8503,4233,5159,56034,2254,207,2249,1019,27006,5295,1871,2257,3845,5605,2260,1956,2248,2246,10000,26281,8817,3082,1870,3265	RAF1,CDKN1A,PDGFA,CCND1,CDH1,PIK3R5,PIK3R2,MITF,PIK3CA,PIK3R3,MET,PDGFRB,PDGFC,FGF9,AKT1,FGF4,CDK4,FGF22,PIK3R1,E2F3,FGF12,KRAS,MAP2K2,FGFR1,EGFR,FGF3,FGF1,AKT3,FGF20,FGF18,HGF,E2F2,HRAS
hsa00603	Glycosphingolipid biosynthesis - globo series	0.458487757902762	-0.779821687963208	14	7	0.00230870712401055	3032	6715	6483,6489,10690,6482,53947,4668,2523	ST3GAL2,ST8SIA1,FUT9,ST3GAL1,A4GALT,NAGA,FUT1
ko00603	Glycosphingolipid biosynthesis - globo series	0.458487757902762	-0.779821687963208	14	7	0.00230870712401055	3032	6715	6483,6489,10690,6482,53947,4668,2523	ST3GAL2,ST8SIA1,FUT9,ST3GAL1,A4GALT,NAGA,FUT1
ko04350	TGF-beta signaling pathway	0.464589353408118	-0.766601374517268	80	37	0.0122031662269129	3032	6715	4052,3397,90,10637,4092,3398,8646,7046,4090,3400,7042,7048,650,3625,5518,4609,268,9241,4091,6199,6667,7044,9978,5515,5308,4088,3399,353500,4087,25805,5933,7027,6500,6198,657,6093,4089	LTBP1,ID1,ACVR1,LEFTY1,SMAD7,ID2,CHRD,TGFBR1,SMAD5,ID4,TGFB2,TGFBR2,BMP2,INHBB,PPP2R1A,MYC,AMH,NOG,SMAD6,RPS6KB2,SP1,LEFTY2,RBX1,PPP2CA,PITX2,SMAD3,ID3,BMP8A,SMAD2,BAMBI,RBL1,TFDP1,SKP1,RPS6KB1,BMPR1A,ROCK1,SMAD4
hsa04350	TGF-beta signaling pathway	0.464589353408118	-0.766601374517268	80	37	0.0122031662269129	3032	6715	4052,3397,90,10637,4092,3398,8646,7046,4090,3400,7042,7048,650,3625,5518,4609,268,9241,4091,6199,6667,7044,9978,5515,5308,4088,3399,353500,4087,25805,5933,7027,6500,6198,657,6093,4089	LTBP1,ID1,ACVR1,LEFTY1,SMAD7,ID2,CHRD,TGFBR1,SMAD5,ID4,TGFB2,TGFBR2,BMP2,INHBB,PPP2R1A,MYC,AMH,NOG,SMAD6,RPS6KB2,SP1,LEFTY2,RBX1,PPP2CA,PITX2,SMAD3,ID3,BMP8A,SMAD2,BAMBI,RBL1,TFDP1,SKP1,RPS6KB1,BMPR1A,ROCK1,SMAD4
hsa00270	Cysteine and methionine metabolism	0.465140412564345	-0.765415956472313	36	17	0.00560686015831135	3032	6715	6723,58478,1788,262,3939,875,4548,23382,92483,27430,55256,10993,191,2805,10768,3945,1491	SRM,ENOPH1,DNMT3A,AMD1,LDHA,CBS,MTR,AHCYL2,LDHAL6B,MAT2B,ADI1,SDS,AHCY,GOT1,AHCYL1,LDHB,CTH
ko05020	Prion diseases	0.465140412564345	-0.765415956472313	36	17	0.00560686015831135	3032	6715	4851,10963,6647,3915,1958,729,3309,5613,5566,5605,3303,733,713,2534,712,714,5567	NOTCH1,STIP1,SOD1,LAMC1,EGR1,C6,HSPA5,PRKX,PRKACA,MAP2K2,HSPA1A,C8G,C1QB,FYN,C1QA,C1QC,PRKACB
hsa03030	DNA replication	0.465140412564345	-0.765415956472313	36	17	0.00560686015831135	3032	6715	5983,5558,84153,3978,4171,5424,246243,6118,4173,5111,5426,4174,29935,5981,57804,4172,5425	RFC3,PRIM2,RNASEH2C,LIG1,MCM2,POLD1,RNASEH1,RPA2,MCM4,PCNA,POLE,MCM5,RPA4,RFC1,POLD4,MCM3,POLD2
ko03030	DNA replication	0.465140412564345	-0.765415956472313	36	17	0.00560686015831135	3032	6715	5983,5558,84153,3978,4171,5424,246243,4173,6118,5111,5426,4174,29935,5981,57804,5425,4172	RFC3,PRIM2,RNASEH2C,LIG1,MCM2,POLD1,RNASEH1,MCM4,RPA2,PCNA,POLE,MCM5,RPA4,RFC1,POLD4,POLD2,MCM3
ko00270	Cysteine and methionine metabolism	0.465140412564345	-0.765415956472313	36	17	0.00560686015831135	3032	6715	6723,58478,1788,262,3939,875,4548,23382,92483,27430,55256,10993,191,2805,10768,3945,1491	SRM,ENOPH1,DNMT3A,AMD1,LDHA,CBS,MTR,AHCYL2,LDHAL6B,MAT2B,ADI1,SDS,AHCY,GOT1,AHCYL1,LDHB,CTH
hsa05340	Primary immunodeficiency	0.465140412564345	-0.765415956472313	36	17	0.00560686015831135	3032	6715	920,115650,5897,6890,29851,29760,23495,4261,100,5788,925,8517,973,326,84876,5993,3543	CD4,TNFRSF13C,RAG2,TAP1,ICOS,BLNK,TNFRSF13B,CIITA,ADA,PTPRC,CD8A,IKBKG,CD79A,AIRE,ORAI1,RFX5,IGLL1
hsa05020	Prion diseases	0.465140412564345	-0.765415956472313	36	17	0.00560686015831135	3032	6715	4851,10963,6647,3915,1958,729,3309,5613,5566,5605,3303,733,713,2534,712,714,5567	NOTCH1,STIP1,SOD1,LAMC1,EGR1,C6,HSPA5,PRKX,PRKACA,MAP2K2,HSPA1A,C8G,C1QB,FYN,C1QA,C1QC,PRKACB
ko05340	Primary immunodeficiency	0.465140412564345	-0.765415956472313	36	17	0.00560686015831135	3032	6715	920,115650,5897,6890,29851,29760,23495,4261,100,5788,925,8517,973,326,84876,5993,3543	CD4,TNFRSF13C,RAG2,TAP1,ICOS,BLNK,TNFRSF13B,CIITA,ADA,PTPRC,CD8A,IKBKG,CD79A,AIRE,ORAI1,RFX5,IGLL1
ko04260	Cardiac muscle contraction	0.472954612888325	-0.748755850932897	78	36	0.0118733509234828	3032	6715	7134,29796,1346,9254,1327,1345,786,7385,6548,779,1537,477,10369,4634,1350,7169,27092,7170,27089,480,7171,6262,481,93589,125965,476,486,440567,9167,1351,9377,7139,784,7168,478,1340	TNNC1,UQCR10,COX7A1,CACNA2D2,COX4I1,COX6C,CACNG1,UQCRC2,SLC9A1,CACNA1S,CYC1,ATP1A2,CACNG2,MYL3,COX7C,TPM2,CACNG4,TPM3,UQCRQ,ATP1A4,TPM4,RYR2,ATP1B1,CACNA2D4,COX6B2,ATP1A1,FXYD2,UQCRHL,COX7A2L,COX8A,COX5A,TNNT2,CACNB3,TPM1,ATP1A3,COX6B1
hsa04260	Cardiac muscle contraction	0.472954612888325	-0.748755850932897	78	36	0.0118733509234828	3032	6715	7134,29796,1346,9254,1327,1345,786,7385,6548,779,1537,477,10369,4634,1350,7169,27092,7170,27089,480,7171,6262,481,93589,125965,476,486,440567,9167,1351,9377,7139,784,7168,478,1340	TNNC1,UQCR10,COX7A1,CACNA2D2,COX4I1,COX6C,CACNG1,UQCRC2,SLC9A1,CACNA1S,CYC1,ATP1A2,CACNG2,MYL3,COX7C,TPM2,CACNG4,TPM3,UQCRQ,ATP1A4,TPM4,RYR2,ATP1B1,CACNA2D4,COX6B2,ATP1A1,FXYD2,UQCRHL,COX7A2L,COX8A,COX5A,TNNT2,CACNB3,TPM1,ATP1A3,COX6B1
hsa_M00002	Glycolysis, core module involving three-carbon compounds	0.477385880669922	-0.739430140986235	12	6	0.00197889182058048	3032	6715	5224,2597,5315,2023,5230,5313	PGAM2,GAPDH,PKM,ENO1,PGK1,PKLR
M00002	Glycolysis, core module involving three-carbon compounds	0.477385880669922	-0.739430140986235	12	6	0.00197889182058048	3032	6715	5224,2597,5315,2023,5230,5313	PGAM2,GAPDH,PKM,ENO1,PGK1,PKLR
ko04724	Glutamatergic synapse	0.489602160538215	-0.714162134929756	116	53	0.0174802110817942	3032	6715	5321,2782,5338,5578,85358,5566,2752,2783,100137049,5331,9456,2890,2793,2899,112,109,51764,5330,2771,116444,6512,5567,123745,113,2912,9229,81539,9455,2788,22941,773,107,2902,5613,2786,2913,3710,9454,283748,2916,2900,8605,255189,111,2917,114,59345,3708,5332,2914,5533,5337,10991	PLA2G4A,GNB1,PLD2,PRKCA,SHANK3,PRKACA,GLUL,GNB2,PLA2G4B,PLCB3,HOMER1,GRIA1,GNGT2,GRIK3,ADCY6,ADCY3,GNG13,PLCB2,GNAI2,GRIN3B,SLC1A7,PRKACB,PLA2G4E,ADCY7,GRM2,DLGAP1,SLC38A1,HOMER2,GNG7,SHANK2,CACNA1A,ADCY1,GRIN1,PRKX,GNG4,GRM3,ITPR3,HOMER3,PLA2G4D,GRM6,GRIK4,PLA2G4C,PLA2G4F,ADCY5,GRM7,ADCY8,GNB4,ITPR1,PLCB4,GRM4,PPP3CC,PLD1,SLC38A3
hsa04724	Glutamatergic synapse	0.489602160538215	-0.714162134929756	116	53	0.0174802110817942	3032	6715	5321,2782,5338,5578,85358,5566,2752,2783,100137049,5331,9456,2890,2793,2899,112,109,51764,5330,2771,116444,6512,5567,123745,113,2912,9229,81539,9455,2788,22941,773,107,2902,5613,2786,2913,3710,9454,283748,2916,2900,8605,255189,111,2917,114,59345,3708,5332,2914,5533,5337,10991	PLA2G4A,GNB1,PLD2,PRKCA,SHANK3,PRKACA,GLUL,GNB2,PLA2G4B,PLCB3,HOMER1,GRIA1,GNGT2,GRIK3,ADCY6,ADCY3,GNG13,PLCB2,GNAI2,GRIN3B,SLC1A7,PRKACB,PLA2G4E,ADCY7,GRM2,DLGAP1,SLC38A1,HOMER2,GNG7,SHANK2,CACNA1A,ADCY1,GRIN1,PRKX,GNG4,GRM3,ITPR3,HOMER3,PLA2G4D,GRM6,GRIK4,PLA2G4C,PLA2G4F,ADCY5,GRM7,ADCY8,GNB4,ITPR1,PLCB4,GRM4,PPP3CC,PLD1,SLC38A3
hsa00250	Alanine, aspartate and glutamate metabolism	0.490449742791355	-0.712432466405929	32	15	0.00494722955145119	3032	6715	790,8659,84706,159,9945,189,440,2875,2747,5471,435,445,2805,122622,2752	CAD,ALDH4A1,GPT2,ADSS,GFPT2,AGXT,ASNS,GPT,GLUD2,PPAT,ASL,ASS1,GOT1,ADSSL1,GLUL
ko00250	Alanine, aspartate and glutamate metabolism	0.490449742791355	-0.712432466405929	32	15	0.00494722955145119	3032	6715	790,8659,84706,159,9945,189,440,2875,2747,5471,435,445,2805,122622,2752	CAD,ALDH4A1,GPT2,ADSS,GFPT2,AGXT,ASNS,GPT,GLUD2,PPAT,ASL,ASS1,GOT1,ADSSL1,GLUL
ko04721	Synaptic vesicle cycle	0.492924602141657	-0.707399053467817	63	29	0.0095646437994723	3032	6715	2054,26052,773,90423,112755,525,533,161,10312,6804,160,23025,127124,1785,10814,5864,10815,527,1211,528,1212,51606,774,6571,8775,594855,9114,8992,9550	STX2,DNM3,CACNA1A,ATP6V1E2,STX1B,ATP6V1B1,ATP6V0B,AP2A2,TCIRG1,STX1A,AP2A1,UNC13A,ATP6V1G3,DNM2,CPLX2,RAB3A,CPLX1,ATP6V0C,CLTA,ATP6V1C1,CLTB,ATP6V1H,CACNA1B,SLC18A2,NAPA,CPLX3,ATP6V0D1,ATP6V0E1,ATP6V1G1
hsa04721	Synaptic vesicle cycle	0.492924602141657	-0.707399053467817	63	29	0.0095646437994723	3032	6715	2054,26052,773,90423,112755,525,533,161,10312,6804,160,23025,127124,1785,10814,5864,10815,527,1211,528,1212,51606,774,6571,8775,594855,9114,8992,9550	STX2,DNM3,CACNA1A,ATP6V1E2,STX1B,ATP6V1B1,ATP6V0B,AP2A2,TCIRG1,STX1A,AP2A1,UNC13A,ATP6V1G3,DNM2,CPLX2,RAB3A,CPLX1,ATP6V0C,CLTA,ATP6V1C1,CLTB,ATP6V1H,CACNA1B,SLC18A2,NAPA,CPLX3,ATP6V0D1,ATP6V0E1,ATP6V1G1
ko00900	Terpenoid backbone biosynthesis	0.493997336693632	-0.705225153117185	21	10	0.00329815303430079	3032	6715	79947,3157,3422,4598,2224,9453,10654,57107,3156,10269	DHDDS,HMGCS1,IDI1,MVK,FDPS,GGPS1,PMVK,PDSS2,HMGCR,ZMPSTE24
hsa00900	Terpenoid backbone biosynthesis	0.493997336693632	-0.705225153117185	21	10	0.00329815303430079	3032	6715	79947,3422,4598,3157,2224,10654,9453,57107,3156,10269	DHDDS,IDI1,MVK,HMGCS1,FDPS,PMVK,GGPS1,PDSS2,HMGCR,ZMPSTE24
hsa_M00095	C5 isoprenoid biosynthesis, mevalonate pathway	0.499576367948323	-0.693994803794397	10	5	0.0016490765171504	3032	6715	3422,4598,3157,10654,3156	IDI1,MVK,HMGCS1,PMVK,HMGCR
M00095	C5 isoprenoid biosynthesis, mevalonate pathway	0.499576367948323	-0.693994803794397	10	5	0.0016490765171504	3032	6715	3422,4598,3157,10654,3156	IDI1,MVK,HMGCS1,PMVK,HMGCR
hsa03440	Homologous recombination	0.519130934806053	-0.655599144770918	28	13	0.00428759894459103	3032	6715	6118,8940,80198,10111,7516,29935,7517,5893,8438,641,5424,57804,5425	RPA2,TOP3B,MUS81,RAD50,XRCC2,RPA4,XRCC3,RAD52,RAD54L,BLM,POLD1,POLD4,POLD2
ko03440	Homologous recombination	0.519130934806053	-0.655599144770918	28	13	0.00428759894459103	3032	6715	6118,8940,80198,10111,7516,29935,7517,5893,8438,641,57804,5424,5425	RPA2,TOP3B,MUS81,RAD50,XRCC2,RPA4,XRCC3,RAD52,RAD54L,BLM,POLD4,POLD1,POLD2
hsa_M00406	TREX complex	0.526633820156062	-0.641249810366412	8	4	0.00131926121372032	3032	6715	79228,10189,57187,84321	THOC6,ALYREF,THOC2,THOC3
hsa_M00077	Chondroitin sulfate degradation	0.526633820156062	-0.641249810366412	8	4	0.00131926121372032	3032	6715	3373,8372,411,8692	HYAL1,HYAL3,ARSB,HYAL2
M00077	Chondroitin sulfate degradation	0.526633820156062	-0.641249810366412	8	4	0.00131926121372032	3032	6715	3373,8372,411,8692	HYAL1,HYAL3,ARSB,HYAL2
M00406	TREX complex	0.526633820156062	-0.641249810366412	8	4	0.00131926121372032	3032	6715	79228,10189,57187,84321	THOC6,ALYREF,THOC2,THOC3
M00065	GPI-anchor biosynthesis, core oligosaccharide	0.526633820156062	-0.641249810366412	8	4	0.00131926121372032	3032	6715	93183,5277,5281,55650	PIGM,PIGA,PIGF,PIGV
hsa_M00065	GPI-anchor biosynthesis, core oligosaccharide	0.526633820156062	-0.641249810366412	8	4	0.00131926121372032	3032	6715	93183,5277,5281,55650	PIGM,PIGA,PIGF,PIGV
ko05132	Salmonella infection	0.527402780724574	-0.639790732561541	86	39	0.0128627968337731	3032	6715	10163,391,1781,81873,71,4627,3606,7082,5585,1432,4628,2317,3725,10092,5216,4790,6351,5601,147700,5600,7100,345456,2318,83547,3460,7879,929,2316,1437,2353,10552,1778,7454,29941,3576,60,6093,4843,6300	WASF2,RHOG,DYNC1I2,ARPC5L,ACTG1,MYH9,IL18,TJP1,PKN1,MAPK14,MYH10,FLNB,JUN,ARPC5,PFN1,NFKB1,CCL4,MAPK9,KLC3,MAPK11,TLR5,PFN3,FLNC,RILP,IFNGR2,RAB7A,CD14,FLNA,CSF2,FOS,ARPC1A,DYNC1H1,WAS,PKN3,IL8,ACTB,ROCK1,NOS2,MAPK12
hsa05132	Salmonella infection	0.527402780724574	-0.639790732561541	86	39	0.0128627968337731	3032	6715	10163,391,1781,81873,71,4627,3606,7082,5585,1432,4628,2317,3725,10092,5216,4790,6351,5601,147700,5600,7100,345456,2318,83547,3460,7879,929,2316,1437,2353,10552,1778,7454,29941,3576,60,6093,4843,6300	WASF2,RHOG,DYNC1I2,ARPC5L,ACTG1,MYH9,IL18,TJP1,PKN1,MAPK14,MYH10,FLNB,JUN,ARPC5,PFN1,NFKB1,CCL4,MAPK9,KLC3,MAPK11,TLR5,PFN3,FLNC,RILP,IFNGR2,RAB7A,CD14,FLNA,CSF2,FOS,ARPC1A,DYNC1H1,WAS,PKN3,IL8,ACTB,ROCK1,NOS2,MAPK12
hsa00910	Nitrogen metabolism	0.530853112873693	-0.633269919597592	17	8	0.00263852242744063	3032	6715	763,766,23632,2747,767,2752,762,771	CA5A,CA7,CA14,GLUD2,CA8,GLUL,CA4,CA12
hsa00450	Selenocompound metabolism	0.530853112873693	-0.633269919597592	17	8	0.00263852242744063	3032	6715	7296,883,9061,56267,4548,51540,22929,1491	TXNRD1,CCBL1,PAPSS1,CCBL2,MTR,SCLY,SEPHS1,CTH
ko00910	Nitrogen metabolism	0.530853112873693	-0.633269919597592	17	8	0.00263852242744063	3032	6715	763,2747,762,771,23632,766,767,2752	CA5A,GLUD2,CA4,CA12,CA14,CA7,CA8,GLUL
ko00450	Selenocompound metabolism	0.530853112873693	-0.633269919597592	17	8	0.00263852242744063	3032	6715	7296,883,9061,56267,4548,51540,22929,1491	TXNRD1,CCBL1,PAPSS1,CCBL2,MTR,SCLY,SEPHS1,CTH
hsa00604	Glycosphingolipid biosynthesis - ganglio series	0.552690796055355	-0.592956572976791	15	7	0.00230870712401055	3032	6715	6483,6489,6482,8705,81849,27090,9197	ST3GAL2,ST8SIA1,ST3GAL1,B3GALT4,ST6GALNAC5,ST6GALNAC4,SLC33A1
ko00604	Glycosphingolipid biosynthesis - ganglio series	0.552690796055355	-0.592956572976791	15	7	0.00230870712401055	3032	6715	6483,6489,6482,8705,81849,27090,9197	ST3GAL2,ST8SIA1,ST3GAL1,B3GALT4,ST6GALNAC5,ST6GALNAC4,SLC33A1
M00395	Decapping complex	0.56160430070467	-0.576957768349946	6	3	0.000989445910290238	3032	6715	55802,219988,167227	DCP1A,PATL1,DCP2
M00029	Urea cycle	0.56160430070467	-0.576957768349946	6	3	0.000989445910290238	3032	6715	445,384,435	ASS1,ARG2,ASL
hsa00061	Fatty acid biosynthesis	0.56160430070467	-0.576957768349946	6	3	0.000989445910290238	3032	6715	27349,55301,2194	MCAT,OLAH,FASN
ko00061	Fatty acid biosynthesis	0.56160430070467	-0.576957768349946	6	3	0.000989445910290238	3032	6715	27349,55301,2194	MCAT,OLAH,FASN
hsa_M00395	Decapping complex	0.56160430070467	-0.576957768349946	6	3	0.000989445910290238	3032	6715	55802,219988,167227	DCP1A,PATL1,DCP2
hsa_M00029	Urea cycle	0.56160430070467	-0.576957768349946	6	3	0.000989445910290238	3032	6715	445,384,435	ASS1,ARG2,ASL
ko04972	Pancreatic secretion	0.56811029967338	-0.565439689547529	96	43	0.0141820580474934	3032	6715	10136,489,6344,81579,6522,5578,8766,5645,5331,1504,4218,1357,112,6548,109,5874,5330,6558,477,1131,113,492,480,219931,3778,491,107,6262,1056,952,481,3784,3710,8399,476,486,111,114,3708,5332,1506,493,478	CELA3A,ATP2A3,SCTR,PLA2G12A,SLC4A2,PRKCA,RAB11A,PRSS2,PLCB3,CTRB1,RAB8A,CPA1,ADCY6,SLC9A1,ADCY3,RAB27B,PLCB2,SLC12A2,ATP1A2,CHRM3,ADCY7,ATP2B3,ATP1A4,TPCN2,KCNMA1,ATP2B2,ADCY1,RYR2,CEL,CD38,ATP1B1,KCNQ1,ITPR3,PLA2G10,ATP1A1,FXYD2,ADCY5,ADCY8,ITPR1,PLCB4,CTRL,ATP2B4,ATP1A3
hsa04972	Pancreatic secretion	0.56811029967338	-0.565439689547529	96	43	0.0141820580474934	3032	6715	10136,489,6344,81579,6522,5578,8766,5645,5331,1504,4218,1357,112,6548,109,5874,5330,6558,477,1131,113,492,480,219931,3778,491,107,6262,1056,952,481,3784,3710,8399,476,486,111,114,3708,5332,1506,493,478	CELA3A,ATP2A3,SCTR,PLA2G12A,SLC4A2,PRKCA,RAB11A,PRSS2,PLCB3,CTRB1,RAB8A,CPA1,ADCY6,SLC9A1,ADCY3,RAB27B,PLCB2,SLC12A2,ATP1A2,CHRM3,ADCY7,ATP2B3,ATP1A4,TPCN2,KCNMA1,ATP2B2,ADCY1,RYR2,CEL,CD38,ATP1B1,KCNQ1,ITPR3,PLA2G10,ATP1A1,FXYD2,ADCY5,ADCY8,ITPR1,PLCB4,CTRL,ATP2B4,ATP1A3
ko05162	Measles	0.568830121645118	-0.564173445416491	134	60	0.0197889182058048	3032	6715	9134,7189,3596,3565,9451,3661,3303,898,595,4179,7161,3654,23533,4790,5296,896,10379,5290,8503,6504,3717,103,54106,57506,6885,6774,3306,4599,2213,29110,207,3460,7128,1019,3312,5295,868,8743,27102,10399,3454,3560,7297,8667,3304,3310,355,2534,9641,23118,10000,4792,356,27113,2932,3665,6776,8793,4478,940	CCNE2,TRAF6,IL13,IL4,EIF2AK3,IRF3,HSPA1A,CCNE1,CCND1,CD46,TP73,IRAK1,PIK3R5,NFKB1,PIK3R2,CCND3,IRF9,PIK3CA,PIK3R3,SLAMF1,JAK2,ADAR,TLR9,MAVS,MAP3K7,STAT3,HSPA2,MX1,FCGR2B,TBK1,AKT1,IFNGR2,TNFAIP3,CDK4,HSPA8,PIK3R1,CBLB,TNFSF10,EIF2AK1,GNB2L1,IFNAR1,IL2RB,TYK2,EIF3H,HSPA1B,HSPA6,FAS,FYN,IKBKE,TAB2,AKT3,NFKBIA,FASLG,BBC3,GSK3B,IRF7,STAT5A,TNFRSF10D,MSN,CD28
hsa05162	Measles	0.568830121645118	-0.564173445416491	134	60	0.0197889182058048	3032	6715	9134,7189,3596,3565,9451,3661,3303,898,595,4179,7161,3654,23533,4790,5296,896,10379,5290,8503,6504,3717,103,54106,57506,6885,6774,3306,4599,2213,29110,207,3460,7128,1019,3312,5295,868,8743,27102,10399,3454,3560,7297,8667,3304,3310,355,2534,9641,23118,10000,4792,356,27113,2932,3665,6776,8793,4478,940	CCNE2,TRAF6,IL13,IL4,EIF2AK3,IRF3,HSPA1A,CCNE1,CCND1,CD46,TP73,IRAK1,PIK3R5,NFKB1,PIK3R2,CCND3,IRF9,PIK3CA,PIK3R3,SLAMF1,JAK2,ADAR,TLR9,MAVS,MAP3K7,STAT3,HSPA2,MX1,FCGR2B,TBK1,AKT1,IFNGR2,TNFAIP3,CDK4,HSPA8,PIK3R1,CBLB,TNFSF10,EIF2AK1,GNB2L1,IFNAR1,IL2RB,TYK2,EIF3H,HSPA1B,HSPA6,FAS,FYN,IKBKE,TAB2,AKT3,NFKBIA,FASLG,BBC3,GSK3B,IRF7,STAT5A,TNFRSF10D,MSN,CD28
ko00380	Tryptophan metabolism	0.568846128135087	-0.564145306497404	40	18	0.00593667546174142	3032	6715	130013,55753,56267,4967,219,2639,847,883,3033,8564,8942,23498,15,4128,501,125061,224,1644	ACMSD,OGDHL,CCBL2,OGDH,ALDH1B1,GCDH,CAT,CCBL1,HADH,KMO,KYNU,HAAO,AANAT,MAOA,ALDH7A1,AFMID,ALDH3A2,DDC
hsa00380	Tryptophan metabolism	0.568846128135087	-0.564145306497404	40	18	0.00593667546174142	3032	6715	130013,55753,56267,4967,219,2639,847,883,3033,8564,8942,23498,15,4128,501,125061,224,1644	ACMSD,OGDHL,CCBL2,OGDH,ALDH1B1,GCDH,CAT,CCBL1,HADH,KMO,KYNU,HAAO,AANAT,MAOA,ALDH7A1,AFMID,ALDH3A2,DDC
hsa04720	Long-term potentiation	0.572044464344986	-0.558538555754681	67	30	0.00989445910290238	3032	6715	468,5894,6195,2902,107,5613,3845,3710,5578,5566,5605,5331,817,2890,6196,51806,816,114,3708,163688,5332,5533,5499,10411,5330,3265,810,818,815,5567	ATF4,RAF1,RPS6KA1,GRIN1,ADCY1,PRKX,KRAS,ITPR3,PRKCA,PRKACA,MAP2K2,PLCB3,CAMK2D,GRIA1,RPS6KA2,CALML5,CAMK2B,ADCY8,ITPR1,CALML6,PLCB4,PPP3CC,PPP1CA,RAPGEF3,PLCB2,HRAS,CALML3,CAMK2G,CAMK2A,PRKACB
ko04720	Long-term potentiation	0.572044464344986	-0.558538555754681	67	30	0.00989445910290238	3032	6715	468,5894,6195,2902,107,5613,3845,3710,5578,5566,5605,5331,817,2890,6196,51806,816,114,3708,163688,5332,5533,5499,10411,5330,3265,810,818,815,5567	ATF4,RAF1,RPS6KA1,GRIN1,ADCY1,PRKX,KRAS,ITPR3,PRKCA,PRKACA,MAP2K2,PLCB3,CAMK2D,GRIA1,RPS6KA2,CALML5,CAMK2B,ADCY8,ITPR1,CALML6,PLCB4,PPP3CC,PPP1CA,RAPGEF3,PLCB2,HRAS,CALML3,CAMK2G,CAMK2A,PRKACB
hsa04726	Serotonergic synapse	0.572163826654393	-0.558329918374968	114	51	0.016820580474934	3032	6715	5321,3358,5894,3763,2782,5578,5566,351,2783,100137049,3352,5331,240,3781,2793,3362,51764,5742,779,10411,5330,2771,5567,1644,1843,123745,1565,3354,2788,773,5613,2786,3845,3710,3360,283748,3363,5743,3762,8605,285242,3765,255189,111,59345,3708,4128,5332,774,6571,3265	PLA2G4A,HTR2C,RAF1,KCNJ6,GNB1,PRKCA,PRKACA,APP,GNB2,PLA2G4B,HTR1D,PLCB3,ALOX5,KCNN2,GNGT2,HTR6,GNG13,PTGS1,CACNA1S,RAPGEF3,PLCB2,GNAI2,PRKACB,DDC,DUSP1,PLA2G4E,CYP2D6,HTR1E,GNG7,CACNA1A,PRKX,GNG4,KRAS,ITPR3,HTR4,PLA2G4D,HTR7,PTGS2,KCNJ5,PLA2G4C,HTR3E,KCNJ9,PLA2G4F,ADCY5,GNB4,ITPR1,MAOA,PLCB4,CACNA1B,SLC18A2,HRAS
hsa03420	Nucleotide excision repair	0.582152464252621	-0.541022899488023	47	21	0.00692612137203166	3032	6715	1643,2967,2067,5983,902,9978,3978,2072,5424,6118,1069,5111,5426,2968,5887,7507,29935,5981,57804,5425,1642	DDB2,GTF2H3,ERCC1,RFC3,CCNH,RBX1,LIG1,ERCC4,POLD1,RPA2,CETN2,PCNA,POLE,GTF2H4,RAD23B,XPA,RPA4,RFC1,POLD4,POLD2,DDB1
ko03420	Nucleotide excision repair	0.582152464252621	-0.541022899488023	47	21	0.00692612137203166	3032	6715	1643,2967,2067,5983,902,9978,3978,2072,5424,6118,1069,5111,5426,2968,5887,7507,29935,5981,57804,1642,5425	DDB2,GTF2H3,ERCC1,RFC3,CCNH,RBX1,LIG1,ERCC4,POLD1,RPA2,CETN2,PCNA,POLE,GTF2H4,RAD23B,XPA,RPA4,RFC1,POLD4,DDB1,POLD2
hsa04622	RIG-I-like receptor signaling pathway	0.603865187818643	-0.504404304935678	70	31	0.0102242744063325	3032	6715	7189,9755,29110,1540,79671,7186,54941,8737,9140,3661,1432,8772,8517,79132,9641,7706,5300,10010,3551,4792,3576,4790,5601,3665,7187,5600,57506,9474,6885,340061,6300	TRAF6,TBKBP1,TBK1,CYLD,NLRX1,TRAF2,RNF125,RIPK1,ATG12,IRF3,MAPK14,FADD,IKBKG,DHX58,IKBKE,TRIM25,PIN1,TANK,IKBKB,NFKBIA,IL8,NFKB1,MAPK9,IRF7,TRAF3,MAPK11,MAVS,ATG5,MAP3K7,TMEM173,MAPK12
ko04622	RIG-I-like receptor signaling pathway	0.603865187818643	-0.504404304935678	70	31	0.0102242744063325	3032	6715	7189,9755,29110,1540,79671,7186,54941,8737,9140,3661,1432,8772,8517,79132,9641,7706,5300,10010,3551,4792,3576,4790,5601,3665,7187,5600,57506,9474,6885,340061,6300	TRAF6,TBKBP1,TBK1,CYLD,NLRX1,TRAF2,RNF125,RIPK1,ATG12,IRF3,MAPK14,FADD,IKBKG,DHX58,IKBKE,TRIM25,PIN1,TANK,IKBKB,NFKBIA,IL8,NFKB1,MAPK9,IRF7,TRAF3,MAPK11,MAVS,ATG5,MAP3K7,TMEM173,MAPK12
M00152	Cytochrome bc1 complex	0.606956927141968	-0.499297450667834	11	5	0.0016490765171504	3032	6715	1537,27089,29796,440567,7385	CYC1,UQCRQ,UQCR10,UQCRHL,UQCRC2
hsa_M00415	Fatty acid biosynthesis, elongation, endoplasmic reticulum	0.606956927141968	-0.499297450667834	11	5	0.0016490765171504	3032	6715	60481,6785,64834,79071,51144	ELOVL5,ELOVL4,ELOVL1,ELOVL6,HSD17B12
hsa_M00152	Cytochrome bc1 complex	0.606956927141968	-0.499297450667834	11	5	0.0016490765171504	3032	6715	1537,27089,29796,440567,7385	CYC1,UQCRQ,UQCR10,UQCRHL,UQCRC2
hsa_M00034	Methionine salvage pathway	0.606956927141968	-0.499297450667834	11	5	0.0016490765171504	3032	6715	6723,58478,27430,55256,262	SRM,ENOPH1,MAT2B,ADI1,AMD1
M00412	ESCRT-III complex	0.606956927141968	-0.499297450667834	11	5	0.0016490765171504	3032	6715	128866,29082,51652,91782,79643	CHMP4B,CHMP4A,CHMP3,CHMP7,CHMP6
M00415	Fatty acid biosynthesis, elongation, endoplasmic reticulum	0.606956927141968	-0.499297450667834	11	5	0.0016490765171504	3032	6715	60481,6785,64834,79071,51144	ELOVL5,ELOVL4,ELOVL1,ELOVL6,HSD17B12
M00034	Methionine salvage pathway	0.606956927141968	-0.499297450667834	11	5	0.0016490765171504	3032	6715	6723,58478,27430,55256,262	SRM,ENOPH1,MAT2B,ADI1,AMD1
hsa_M00412	ESCRT-III complex	0.606956927141968	-0.499297450667834	11	5	0.0016490765171504	3032	6715	128866,29082,51652,91782,79643	CHMP4B,CHMP4A,CHMP3,CHMP7,CHMP6
hsa_M00288	RPA complex	0.611552528559737	-0.491754426383554	4	2	0.000659630606860158	3032	6715	6118,29935	RPA2,RPA4
M00288	RPA complex	0.611552528559737	-0.491754426383554	4	2	0.000659630606860158	3032	6715	6118,29935	RPA2,RPA4
hsa_M00082	Fatty acid biosynthesis, initiation	0.611552528559737	-0.491754426383554	4	2	0.000659630606860158	3032	6715	27349,2194	MCAT,FASN
M00381	SCF-SKP2 complex	0.611552528559737	-0.491754426383554	4	2	0.000659630606860158	3032	6715	6500,9978	SKP1,RBX1
M00020	Serine biosynthesis, glycerate-3P => serine	0.611552528559737	-0.491754426383554	4	2	0.000659630606860158	3032	6715	29968,5723	PSAT1,PSPH
M00015	Proline biosynthesis, glutamate => proline	0.611552528559737	-0.491754426383554	4	2	0.000659630606860158	3032	6715	29920,65263	PYCR2,PYCRL
hsa_M00020	Serine biosynthesis, glycerate-3P => serine	0.611552528559737	-0.491754426383554	4	2	0.000659630606860158	3032	6715	29968,5723	PSAT1,PSPH
hsa_M00381	SCF-SKP2 complex	0.611552528559737	-0.491754426383554	4	2	0.000659630606860158	3032	6715	6500,9978	SKP1,RBX1
M00082	Fatty acid biosynthesis, initiation	0.611552528559737	-0.491754426383554	4	2	0.000659630606860158	3032	6715	27349,2194	MCAT,FASN
hsa_M00425	H/ACA ribonucleoprotein complex	0.611552528559737	-0.491754426383554	4	2	0.000659630606860158	3032	6715	1736,55651	DKC1,NHP2
hsa_M00015	Proline biosynthesis, glutamate => proline	0.611552528559737	-0.491754426383554	4	2	0.000659630606860158	3032	6715	29920,65263	PYCR2,PYCRL
hsa_M00148	Succinate dehydrogenase (ubiquinone)	0.611552528559737	-0.491754426383554	4	2	0.000659630606860158	3032	6715	6390,6391	SDHB,SDHC
M00148	Succinate dehydrogenase (ubiquinone)	0.611552528559737	-0.491754426383554	4	2	0.000659630606860158	3032	6715	6390,6391	SDHB,SDHC
M00425	H/ACA ribonucleoprotein complex	0.611552528559737	-0.491754426383554	4	2	0.000659630606860158	3032	6715	1736,55651	DKC1,NHP2
hsa00360	Phenylalanine metabolism	0.613738214411418	-0.4881868026461	18	8	0.00263852242744063	3032	6715	4128,2805,221,9588,1644,218,220,222	MAOA,GOT1,ALDH3B1,PRDX6,DDC,ALDH3A1,ALDH1A3,ALDH3B2
M00181	RNA polymerase III, eukaryotes	0.613738214411418	-0.4881868026461	18	8	0.00263852242744063	3032	6715	84265,661,5437,5441,5440,51728,55718,5434	POLR3GL,POLR3D,POLR2H,POLR2L,POLR2K,POLR3K,POLR3E,POLR2E
ko00360	Phenylalanine metabolism	0.613738214411418	-0.4881868026461	18	8	0.00263852242744063	3032	6715	221,9588,218,220,4128,2805,1644,222	ALDH3B1,PRDX6,ALDH3A1,ALDH1A3,MAOA,GOT1,DDC,ALDH3B2
hsa_M00181	RNA polymerase III, eukaryotes	0.613738214411418	-0.4881868026461	18	8	0.00263852242744063	3032	6715	84265,661,5437,5441,5440,51728,55718,5434	POLR3GL,POLR3D,POLR2H,POLR2L,POLR2K,POLR3K,POLR3E,POLR2E
hsa04621	NOD-like receptor signaling pathway	0.627935681654275	-0.465317535506963	57	25	0.00824538258575198	3032	6715	7189,330,7128,7205,22861,114548,3326,64170,3606,1432,329,10910,8517,23118,3551,4792,3576,5601,4790,64127,5600,3320,6885,9051,6300	TRAF6,BIRC3,TNFAIP3,TRIP6,NLRP1,NLRP3,HSP90AB1,CARD9,IL18,MAPK14,BIRC2,SUGT1,IKBKG,TAB2,IKBKB,NFKBIA,IL8,MAPK9,NFKB1,NOD2,MAPK11,HSP90AA1,MAP3K7,PSTPIP1,MAPK12
ko04621	NOD-like receptor signaling pathway	0.627935681654275	-0.465317535506963	57	25	0.00824538258575198	3032	6715	7189,330,7128,7205,22861,114548,3326,64170,3606,1432,329,10910,8517,23118,3551,4792,3576,5601,4790,64127,5600,3320,6885,9051,6300	TRAF6,BIRC3,TNFAIP3,TRIP6,NLRP1,NLRP3,HSP90AB1,CARD9,IL18,MAPK14,BIRC2,SUGT1,IKBKG,TAB2,IKBKB,NFKBIA,IL8,MAPK9,NFKB1,NOD2,MAPK11,HSP90AA1,MAP3K7,PSTPIP1,MAPK12
M00295	BRCA1-associated genome surveillance complex (BASC)	0.638809245116209	-0.44814939011575	16	7	0.00230870712401055	3032	6715	472,5981,672,5111,5983,641,10111	ATM,RFC1,BRCA1,PCNA,RFC3,BLM,RAD50
hsa_M00295	BRCA1-associated genome surveillance complex (BASC)	0.638809245116209	-0.44814939011575	16	7	0.00230870712401055	3032	6715	472,5981,672,5111,5983,641,10111	ATM,RFC1,BRCA1,PCNA,RFC3,BLM,RAD50
ko03430	Mismatch repair	0.642184184550675	-0.442880124614284	23	10	0.00329815303430079	3032	6715	6118,9156,5983,5111,29935,3978,5981,57804,5424,5425	RPA2,EXO1,RFC3,PCNA,RPA4,LIG1,RFC1,POLD4,POLD1,POLD2
hsa03430	Mismatch repair	0.642184184550675	-0.442880124614284	23	10	0.00329815303430079	3032	6715	9156,6118,5111,5983,29935,3978,5981,57804,5424,5425	EXO1,RPA2,PCNA,RFC3,RPA4,LIG1,RFC1,POLD4,POLD1,POLD2
ko00020	Citrate cycle (TCA cycle)	0.647455995602259	-0.434704448177692	30	13	0.00428759894459103	3032	6715	6390,5160,5091,6391,47,55753,5105,48,2271,5161,3418,4967,1743	SDHB,PDHA1,PC,SDHC,ACLY,OGDHL,PCK1,ACO1,FH,PDHA2,IDH2,OGDH,DLST
hsa00020	Citrate cycle (TCA cycle)	0.647455995602259	-0.434704448177692	30	13	0.00428759894459103	3032	6715	6390,5160,5091,6391,55753,48,5105,47,2271,5161,3418,4967,1743	SDHB,PDHA1,PC,SDHC,OGDHL,ACO1,PCK1,ACLY,FH,PDHA2,IDH2,OGDH,DLST
ko03013	RNA transport	0.656505037877307	-0.420824911426679	164	72	0.0237467018469657	3032	6715	55706,79228,8663,9939,8664,1964,3646,51367,7329,10289,23225,55520,55746,1983,1977,10460,81929,54913,29107,10557,10921,6612,60528,5411,8021,8666,11260,8667,25929,1981,7514,1978,8662,8891,96764,8086,84321,253314,6396,10250,8672,10775,1915,129401,11097,10189,10209,10419,26986,79902,3837,23191,1975,91181,5905,1973,9513,8890,26999,728689,1982,59343,10940,7175,5042,5976,1968,57187,9688,8892,22916,51808	NDC1,THOC6,EIF3C,RBM8A,EIF3D,EIF1AX,EIF3E,POP5,UBE2I,EIF1B,NUP210,ELAC1,NUP133,EIF5,EIF4E,TACC3,SEH1L,RPP25,NXT1,RPP38,RNPS1,SUMO3,ELAC2,PNN,NUP214,EIF3G,XPOT,EIF3H,GEMIN5,EIF4G1,XPO1,EIF4EBP1,EIF3B,EIF2B3,TGS1,AAAS,THOC3,EIF4E1B,SEC13,SRRM1,EIF4G3,POP4,EEF1A1,NUP35,NUPL2,ALYREF,EIF1,PRMT5,PABPC1,NUP85,KPNB1,CYFIP1,EIF4B,NUP210L,RANGAP1,EIF4A1,FXR2,EIF2B4,CYFIP2,EIF3CL,EIF4G2,SENP2,POP1,TPR,PABPC3,UPF1,EIF2S3,THOC2,NUP93,EIF2B2,NCBP2,PHAX
hsa03013	RNA transport	0.656505037877307	-0.420824911426679	164	72	0.0237467018469657	3032	6715	55706,79228,8663,9939,8664,1964,3646,51367,7329,10289,23225,55520,55746,1983,1977,10460,81929,54913,29107,10557,10921,6612,60528,5411,8021,8666,11260,8667,25929,1981,7514,1978,8662,8891,96764,8086,84321,253314,6396,10250,8672,10775,1915,129401,11097,10189,10209,10419,26986,79902,3837,23191,1975,91181,5905,1973,9513,8890,26999,728689,1982,59343,10940,7175,5042,5976,1968,57187,9688,8892,22916,51808	NDC1,THOC6,EIF3C,RBM8A,EIF3D,EIF1AX,EIF3E,POP5,UBE2I,EIF1B,NUP210,ELAC1,NUP133,EIF5,EIF4E,TACC3,SEH1L,RPP25,NXT1,RPP38,RNPS1,SUMO3,ELAC2,PNN,NUP214,EIF3G,XPOT,EIF3H,GEMIN5,EIF4G1,XPO1,EIF4EBP1,EIF3B,EIF2B3,TGS1,AAAS,THOC3,EIF4E1B,SEC13,SRRM1,EIF4G3,POP4,EEF1A1,NUP35,NUPL2,ALYREF,EIF1,PRMT5,PABPC1,NUP85,KPNB1,CYFIP1,EIF4B,NUP210L,RANGAP1,EIF4A1,FXR2,EIF2B4,CYFIP2,EIF3CL,EIF4G2,SENP2,POP1,TPR,PABPC3,UPF1,EIF2S3,THOC2,NUP93,EIF2B2,NCBP2,PHAX
hsa03008	Ribosome biogenesis in eukaryotes	0.658766105641027	-0.417386730634499	85	37	0.0122031662269129	3032	6715	84128,27341,28987,10813,55226,10885,10775,29889,51367,79631,55651,51119,3692,4931,51096,2091,23160,92856,54913,29107,10557,23560,25996,5822,9790,166378,1736,55272,254958,10940,7514,10607,57455,54552,6949,55127,10171	WDR75,RRP7A,NOB1,UTP14A,NAT10,WDR3,POP4,GNL2,POP5,EFTUD1,NHP2,SBDS,EIF6,NVL,UTP18,FBL,WDR43,IMP4,RPP25,NXT1,RPP38,GTPBP4,REXO2,PWP2,BMS1,SPATA5,DKC1,IMP3,REXO1L1P,POP1,XPO1,TBL3,REXO1,GNL3L,TCOF1,HEATR1,RCL1
ko03008	Ribosome biogenesis in eukaryotes	0.658766105641027	-0.417386730634499	85	37	0.0122031662269129	3032	6715	84128,27341,28987,10813,55226,10885,10775,29889,51367,79631,55651,51119,3692,4931,51096,2091,23160,92856,54913,29107,10557,23560,25996,5822,9790,166378,1736,55272,254958,10940,7514,10607,57455,54552,6949,55127,10171	WDR75,RRP7A,NOB1,UTP14A,NAT10,WDR3,POP4,GNL2,POP5,EFTUD1,NHP2,SBDS,EIF6,NVL,UTP18,FBL,WDR43,IMP4,RPP25,NXT1,RPP38,GTPBP4,REXO2,PWP2,BMS1,SPATA5,DKC1,IMP3,REXO1L1P,POP1,XPO1,TBL3,REXO1,GNL3L,TCOF1,HEATR1,RCL1
hsa02010	ABC transporters	0.659387201269103	-0.416444358194533	44	19	0.0062664907651715	3032	6715	10058,94160,340273,10257,6890,23456,1244,23457,10347,10351,6833,368,5825,23461,20,215,8714,11194,9619	ABCB6,ABCC12,ABCB5,ABCC4,TAP1,ABCB10,ABCC2,ABCB9,ABCA7,ABCA8,ABCC8,ABCC6,ABCD3,ABCA5,ABCA2,ABCD1,ABCC3,ABCB8,ABCG1
ko02010	ABC transporters	0.659387201269103	-0.416444358194533	44	19	0.0062664907651715	3032	6715	10058,94160,340273,10257,6890,23456,1244,23457,10351,10347,6833,368,23461,5825,20,215,8714,11194,9619	ABCB6,ABCC12,ABCB5,ABCC4,TAP1,ABCB10,ABCC2,ABCB9,ABCA8,ABCA7,ABCC8,ABCC6,ABCA5,ABCD3,ABCA2,ABCD1,ABCC3,ABCB8,ABCG1
hsa05140	Leishmaniasis	0.66186652865153	-0.412691361724004	76	33	0.0108839050131926	3032	6715	7189,3565,7042,1432,4688,3123,3113,3725,3654,2209,653361,4790,3717,5600,9103,6885,718,4689,3460,5777,65108,3586,2353,2214,3689,5743,23118,1378,4792,2212,3688,4843,6300	TRAF6,IL4,TGFB2,MAPK14,NCF2,HLA-DRB1,HLA-DPA1,JUN,IRAK1,FCGR1A,NCF1,NFKB1,JAK2,MAPK11,FCGR2C,MAP3K7,C3,NCF4,IFNGR2,PTPN6,MARCKSL1,IL10,FOS,FCGR3A,ITGB2,PTGS2,TAB2,CR1,NFKBIA,FCGR2A,ITGB1,NOS2,MAPK12
ko05140	Leishmaniasis	0.66186652865153	-0.412691361724004	76	33	0.0108839050131926	3032	6715	7189,3565,7042,1432,4688,3123,3113,3725,3654,2209,653361,4790,3717,5600,9103,6885,718,4689,3460,5777,65108,3586,2353,2214,3689,5743,23118,1378,4792,2212,3688,4843,6300	TRAF6,IL4,TGFB2,MAPK14,NCF2,HLA-DRB1,HLA-DPA1,JUN,IRAK1,FCGR1A,NCF1,NFKB1,JAK2,MAPK11,FCGR2C,MAP3K7,C3,NCF4,IFNGR2,PTPN6,MARCKSL1,IL10,FOS,FCGR3A,ITGB2,PTGS2,TAB2,CR1,NFKBIA,FCGR2A,ITGB1,NOS2,MAPK12
ko00030	Pentose phosphate pathway	0.665928415204244	-0.406573098896953	28	12	0.00395778364116095	3032	6715	5236,25796,5211,226,7086,51071,2821,6888,6120,5226,22934,9563	PGM1,PGLS,PFKL,ALDOA,TKT,DERA,GPI,TALDO1,RPE,PGD,RPIA,H6PD
hsa00030	Pentose phosphate pathway	0.665928415204244	-0.406573098896953	28	12	0.00395778364116095	3032	6715	5236,25796,5211,226,7086,51071,2821,6888,6120,22934,9563,5226	PGM1,PGLS,PFKL,ALDOA,TKT,DERA,GPI,TALDO1,RPE,RPIA,H6PD,PGD
hsa_M00353	Spliceosome, Prp19/CDC5L complex	0.667097988795982	-0.404818334117588	14	6	0.00197889182058048	3032	6715	56259,3306,3303,3312,3304,3310	CTNNBL1,HSPA2,HSPA1A,HSPA8,HSPA1B,HSPA6
M00011	Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate	0.667097988795982	-0.404818334117588	14	6	0.00197889182058048	3032	6715	6390,4967,1743,6391,55753,2271	SDHB,OGDH,DLST,SDHC,OGDHL,FH
M00353	Spliceosome, Prp19/CDC5L complex	0.667097988795982	-0.404818334117588	14	6	0.00197889182058048	3032	6715	56259,3306,3303,3312,3304,3310	CTNNBL1,HSPA2,HSPA1A,HSPA8,HSPA1B,HSPA6
hsa_M00011	Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate	0.667097988795982	-0.404818334117588	14	6	0.00197889182058048	3032	6715	6390,4967,1743,6391,55753,2271	SDHB,OGDH,DLST,SDHC,OGDHL,FH
hsa04727	GABAergic synapse	0.674648682329129	-0.39356319422497	90	39	0.0128627968337731	3032	6715	3763,2566,2565,2782,6538,2570,5578,5566,2752,6714,2783,2793,2568,112,109,51764,779,57468,2771,5567,2567,113,10243,81539,9568,2788,773,107,5613,11345,2786,9001,23710,2554,111,114,59345,774,10991	KCNJ6,GABRG2,GABRG1,GNB1,SLC6A11,GABRR2,PRKCA,PRKACA,GLUL,SRC,GNB2,GNGT2,GABRP,ADCY6,ADCY3,GNG13,CACNA1S,SLC12A5,GNAI2,PRKACB,GABRG3,ADCY7,GPHN,SLC38A1,GABBR2,GNG7,CACNA1A,ADCY1,PRKX,GABARAPL2,GNG4,HAP1,GABARAPL1,GABRA1,ADCY5,ADCY8,GNB4,CACNA1B,SLC38A3
ko04727	GABAergic synapse	0.674648682329129	-0.39356319422497	90	39	0.0128627968337731	3032	6715	3763,2566,2565,2782,6538,2570,5578,5566,2752,6714,2783,2793,2568,112,109,51764,779,57468,2771,5567,2567,113,10243,81539,9568,2788,773,107,5613,11345,2786,9001,23710,2554,111,114,59345,774,10991	KCNJ6,GABRG2,GABRG1,GNB1,SLC6A11,GABRR2,PRKCA,PRKACA,GLUL,SRC,GNB2,GNGT2,GABRP,ADCY6,ADCY3,GNG13,CACNA1S,SLC12A5,GNAI2,PRKACB,GABRG3,ADCY7,GPHN,SLC38A1,GABBR2,GNG7,CACNA1A,ADCY1,PRKX,GABARAPL2,GNG4,HAP1,GABARAPL1,GABRA1,ADCY5,ADCY8,GNB4,CACNA1B,SLC38A3
hsa05144	Malaria	0.678627986274299	-0.387682186288328	49	21	0.00692612137203166	3032	6715	7058,6403,3606,7059,3586,7042,6382,948,2532,3383,3689,1440,2995,1378,3576,3082,54106,4233,1311,975,22914	THBS2,SELP,IL18,THBS3,IL10,TGFB2,SDC1,CD36,DARC,ICAM1,ITGB2,CSF3,GYPC,CR1,IL8,HGF,TLR9,MET,COMP,CD81,KLRK1
ko05144	Malaria	0.678627986274299	-0.387682186288328	49	21	0.00692612137203166	3032	6715	7058,6403,3606,7059,3586,7042,6382,948,2532,3383,3689,1440,2995,1378,3576,3082,54106,4233,1311,975,22914	THBS2,SELP,IL18,THBS3,IL10,TGFB2,SDC1,CD36,DARC,ICAM1,ITGB2,CSF3,GYPC,CR1,IL8,HGF,TLR9,MET,COMP,CD81,KLRK1
ko04630	Jak-STAT signaling pathway	0.683018769003455	-0.381232939549602	156	68	0.0224274406332454	3032	6715	200734,3601,3600,1270,8835,3596,29949,53833,7173,1441,595,8554,8651,3572,5296,11009,5290,8503,3566,3588,3562,3976,207,5777,23529,868,3578,3586,867,7297,9021,10401,6778,81848,51588,3565,50615,2688,4352,1440,1154,23533,4609,896,5618,5781,10379,3952,3717,5292,6774,10253,2057,3460,3590,6775,5295,3570,1437,3454,3560,10254,10000,9180,50604,6776,3581,3567	SPRED2,IL15RA,IL15,CNTF,SOCS2,IL13,IL19,IL20RB,TPO,CSF3R,CCND1,PIAS1,SOCS1,IL6ST,PIK3R2,IL24,PIK3CA,PIK3R3,IL4R,IL10RB,IL3,LIF,AKT1,PTPN6,CLCF1,CBLB,IL9,IL10,CBL,TYK2,SOCS3,PIAS3,STAT6,SPRY4,PIAS4,IL4,IL21R,GH1,MPL,CSF3,CISH,PIK3R5,MYC,CCND3,PRLR,PTPN11,IRF9,LEP,JAK2,PIM1,STAT3,SPRY2,EPOR,IFNGR2,IL11RA,STAT4,PIK3R1,IL6R,CSF2,IFNAR1,IL2RB,STAM2,AKT3,OSMR,IL20,STAT5A,IL9R,IL5
hsa04630	Jak-STAT signaling pathway	0.683018769003455	-0.381232939549602	156	68	0.0224274406332454	3032	6715	200734,3601,3600,1270,8835,3596,29949,53833,7173,1441,595,8554,8651,3572,5296,11009,5290,8503,3566,3588,3562,3976,207,5777,23529,868,3578,3586,867,7297,9021,10401,6778,81848,51588,3565,50615,2688,4352,1440,1154,23533,4609,896,5618,5781,10379,3952,3717,5292,6774,10253,2057,3460,3590,6775,5295,3570,1437,3454,3560,10254,10000,9180,50604,6776,3581,3567	SPRED2,IL15RA,IL15,CNTF,SOCS2,IL13,IL19,IL20RB,TPO,CSF3R,CCND1,PIAS1,SOCS1,IL6ST,PIK3R2,IL24,PIK3CA,PIK3R3,IL4R,IL10RB,IL3,LIF,AKT1,PTPN6,CLCF1,CBLB,IL9,IL10,CBL,TYK2,SOCS3,PIAS3,STAT6,SPRY4,PIAS4,IL4,IL21R,GH1,MPL,CSF3,CISH,PIK3R5,MYC,CCND3,PRLR,PTPN11,IRF9,LEP,JAK2,PIM1,STAT3,SPRY2,EPOR,IFNGR2,IL11RA,STAT4,PIK3R1,IL6R,CSF2,IFNAR1,IL2RB,STAM2,AKT3,OSMR,IL20,STAT5A,IL9R,IL5
hsa00460	Cyanoamino acid metabolism	0.686625787751633	-0.375965840039278	7	3	0.000989445910290238	3032	6715	2678,6470,2687	GGT1,SHMT1,GGT5
M00398	Sm core complex	0.686625787751633	-0.375965840039278	7	3	0.000989445910290238	3032	6715	6635,6632,6628	SNRPE,SNRPD1,SNRPB
M00397	Lsm 1-7 complex	0.686625787751633	-0.375965840039278	7	3	0.000989445910290238	3032	6715	25804,27257,11157	LSM4,LSM1,LSM6
hsa_M00398	Sm core complex	0.686625787751633	-0.375965840039278	7	3	0.000989445910290238	3032	6715	6635,6632,6628	SNRPE,SNRPD1,SNRPB
hsa_M00397	Lsm 1-7 complex	0.686625787751633	-0.375965840039278	7	3	0.000989445910290238	3032	6715	25804,27257,11157	LSM4,LSM1,LSM6
ko00460	Cyanoamino acid metabolism	0.686625787751633	-0.375965840039278	7	3	0.000989445910290238	3032	6715	2678,6470,2687	GGT1,SHMT1,GGT5
ko05152	Tuberculosis	0.686722179628552	-0.37582546501508	181	79	0.0260554089709763	3032	6715	3916,7189,2207,5894,537,3606,1432,637,8411,3113,533,2209,4790,9103,54106,3687,3588,815,718,1263,207,7879,5868,929,3586,820,5869,3689,7421,817,4800,10312,7132,64127,5533,527,56848,6300,9902,64170,8877,54205,7042,6714,3123,1520,51806,3654,5601,3717,5600,4046,5993,1509,1385,51606,6850,9114,818,2213,3460,10892,23365,972,4261,8772,2214,1051,3313,1378,10000,816,1054,163688,2212,317,5878,4843,810	LAMP1,TRAF6,FCER1G,RAF1,ATP6AP1,IL18,MAPK14,BID,EEA1,HLA-DPA1,ATP6V0B,FCGR1A,NFKB1,FCGR2C,TLR9,ITGAX,IL10RB,CAMK2A,C3,PLK3,AKT1,RAB7A,RAB5A,CD14,IL10,CAMP,RAB5B,ITGB2,VDR,CAMK2D,NFYA,TCIRG1,TNFRSF1A,NOD2,PPP3CC,ATP6V0C,SPHK2,MAPK12,MRC2,CARD9,SPHK1,CYCS,TGFB2,SRC,HLA-DRB1,CTSS,CALML5,IRAK1,MAPK9,JAK2,MAPK11,LSP1,RFX5,CTSD,CREB1,ATP6V1H,SYK,ATP6V0D1,CAMK2G,FCGR2B,IFNGR2,MALT1,ARHGEF12,CD74,CIITA,FADD,FCGR3A,CEBPB,HSPA9,CR1,AKT3,CAMK2B,CEBPG,CALML6,FCGR2A,APAF1,RAB5C,NOS2,CALML3
hsa05152	Tuberculosis	0.686722179628552	-0.37582546501508	181	79	0.0260554089709763	3032	6715	3916,7189,2207,5894,537,3606,1432,637,8411,3113,533,2209,4790,9103,54106,3687,3588,815,718,1263,207,7879,5868,929,3586,820,5869,3689,7421,817,4800,10312,7132,64127,5533,527,56848,6300,9902,64170,8877,54205,7042,6714,3123,1520,51806,3654,5601,3717,5600,4046,5993,1509,1385,51606,6850,9114,818,2213,3460,10892,23365,972,4261,8772,2214,1051,3313,1378,10000,816,1054,163688,2212,317,5878,4843,810	LAMP1,TRAF6,FCER1G,RAF1,ATP6AP1,IL18,MAPK14,BID,EEA1,HLA-DPA1,ATP6V0B,FCGR1A,NFKB1,FCGR2C,TLR9,ITGAX,IL10RB,CAMK2A,C3,PLK3,AKT1,RAB7A,RAB5A,CD14,IL10,CAMP,RAB5B,ITGB2,VDR,CAMK2D,NFYA,TCIRG1,TNFRSF1A,NOD2,PPP3CC,ATP6V0C,SPHK2,MAPK12,MRC2,CARD9,SPHK1,CYCS,TGFB2,SRC,HLA-DRB1,CTSS,CALML5,IRAK1,MAPK9,JAK2,MAPK11,LSP1,RFX5,CTSD,CREB1,ATP6V1H,SYK,ATP6V0D1,CAMK2G,FCGR2B,IFNGR2,MALT1,ARHGEF12,CD74,CIITA,FADD,FCGR3A,CEBPB,HSPA9,CR1,AKT3,CAMK2B,CEBPG,CALML6,FCGR2A,APAF1,RAB5C,NOS2,CALML3
M00427	Nuclear pore complex	0.688910243441596	-0.372644287221366	40	17	0.00560686015831135	3032	6715	6396,55706,91181,6612,5905,7329,8021,129401,59343,11097,7175,23225,55746,9688,79902,8086,81929	SEC13,NDC1,NUP210L,SUMO3,RANGAP1,UBE2I,NUP214,NUP35,SENP2,NUPL2,TPR,NUP210,NUP133,NUP93,NUP85,AAAS,SEH1L
hsa_M00427	Nuclear pore complex	0.688910243441596	-0.372644287221366	40	17	0.00560686015831135	3032	6715	6396,55706,91181,6612,5905,7329,8021,129401,59343,11097,7175,23225,55746,9688,79902,8086,81929	SEC13,NDC1,NUP210L,SUMO3,RANGAP1,UBE2I,NUP214,NUP35,SENP2,NUPL2,TPR,NUP210,NUP133,NUP93,NUP85,AAAS,SEH1L
hsa_M00399	Cap binding complex	0.699213632336889	-0.35779895778155	2	1	0.000329815303430079	3032	6715	22916	NCBP2
hsa00300	Lysine biosynthesis	0.699213632336889	-0.35779895778155	2	1	0.000329815303430079	3032	6715	501	ALDH7A1
M00103	Cholecalciferol biosynthesis	0.699213632336889	-0.35779895778155	2	1	0.000329815303430079	3032	6715	120227	CYP2R1
hsa_M00083	Fatty acid biosynthesis, elongation	0.699213632336889	-0.35779895778155	2	1	0.000329815303430079	3032	6715	2194	FASN
hsa_M00103	Cholecalciferol biosynthesis	0.699213632336889	-0.35779895778155	2	1	0.000329815303430079	3032	6715	120227	CYP2R1
M00083	Fatty acid biosynthesis, elongation	0.699213632336889	-0.35779895778155	2	1	0.000329815303430079	3032	6715	2194	FASN
M00399	Cap binding complex	0.699213632336889	-0.35779895778155	2	1	0.000329815303430079	3032	6715	22916	NCBP2
ko00300	Lysine biosynthesis	0.699213632336889	-0.35779895778155	2	1	0.000329815303430079	3032	6715	501	ALDH7A1
M00068	Glycosphingolipid biosynthesis, globo-series, LacCer => Gb4Cer	0.699213632336889	-0.35779895778155	2	1	0.000329815303430079	3032	6715	53947	A4GALT
hsa_M00068	Glycosphingolipid biosynthesis, globo-series, LacCer => Gb4Cer	0.699213632336889	-0.35779895778155	2	1	0.000329815303430079	3032	6715	53947	A4GALT
hsa_M00182	RNA polymerase I, eukaryotes	0.699507674626458	-0.357378513347856	12	5	0.0016490765171504	3032	6715	5437,5441,5440,64425,5434	POLR2H,POLR2L,POLR2K,POLR1E,POLR2E
M00182	RNA polymerase I, eukaryotes	0.699507674626458	-0.357378513347856	12	5	0.0016490765171504	3032	6715	5437,5441,5440,64425,5434	POLR2H,POLR2L,POLR2K,POLR1E,POLR2E
M00154	Cytochrome c oxidase	0.706454401302109	-0.347496620621834	24	10	0.00329815303430079	3032	6715	1350,125965,1346,9167,1351,9377,1327,1345,1352,1340	COX7C,COX6B2,COX7A1,COX7A2L,COX8A,COX5A,COX4I1,COX6C,COX10,COX6B1
hsa_M00154	Cytochrome c oxidase	0.706454401302109	-0.347496620621834	24	10	0.00329815303430079	3032	6715	1350,125965,1346,9167,1351,9377,1327,1345,1352,1340	COX7C,COX6B2,COX7A1,COX7A2L,COX8A,COX5A,COX4I1,COX6C,COX10,COX6B1
ko03015	mRNA surveillance pathway	0.70759946730513	-0.345877069515995	91	39	0.0128627968337731	3032	6715	10250,9939,10978,9887,10914,29894,23381,10189,5518,2107,5499,5521,10898,26986,1477,124540,28227,29107,10921,5411,51585,8189,390748,5515,5529,5042,5976,5525,29101,1478,22916,2935,55339,5522,55844,5528,23049,8106,79869	SRRM1,RBM8A,CLP1,SMG7,PAPOLA,CPSF1,SMG5,ALYREF,PPP2R1A,ETF1,PPP1CA,PPP2R2B,CPSF4,PABPC1,CSTF1,MSI2,PPP2R3B,NXT1,RNPS1,PNN,PCF11,SYMPK,PABPN1L,PPP2CA,PPP2R5E,PABPC3,UPF1,PPP2R5A,SSU72,CSTF2,NCBP2,GSPT1,WDR33,PPP2R2C,PPP2R2D,PPP2R5D,SMG1,PABPN1,CPSF7
hsa03015	mRNA surveillance pathway	0.70759946730513	-0.345877069515995	91	39	0.0128627968337731	3032	6715	10250,9939,10978,9887,10914,29894,23381,10189,5518,2107,5499,5521,10898,26986,1477,124540,28227,29107,10921,5411,51585,8189,390748,5515,5529,5042,5976,5525,29101,1478,22916,2935,55339,5522,55844,5528,23049,8106,79869	SRRM1,RBM8A,CLP1,SMG7,PAPOLA,CPSF1,SMG5,ALYREF,PPP2R1A,ETF1,PPP1CA,PPP2R2B,CPSF4,PABPC1,CSTF1,MSI2,PPP2R3B,NXT1,RNPS1,PNN,PCF11,SYMPK,PABPN1L,PPP2CA,PPP2R5E,PABPC3,UPF1,PPP2R5A,SSU72,CSTF2,NCBP2,GSPT1,WDR33,PPP2R2C,PPP2R2D,PPP2R5D,SMG1,PABPN1,CPSF7
hsa00770	Pantothenate and CoA biosynthesis	0.714378537698887	-0.336342292285901	17	7	0.00230870712401055	3032	6715	5167,60496,55229,79646,1807,53354,60490	ENPP1,AASDHPPT,PANK4,PANK3,DPYS,PANK1,PPCDC
hsa04614	Renin-angiotensin system	0.714378537698887	-0.336342292285901	17	7	0.00230870712401055	3032	6715	183,1636,5972,4311,7064,4012,290	AGT,ACE,REN,MME,THOP1,LNPEP,ANPEP
ko04614	Renin-angiotensin system	0.714378537698887	-0.336342292285901	17	7	0.00230870712401055	3032	6715	183,1636,5972,4311,7064,4012,290	AGT,ACE,REN,MME,THOP1,LNPEP,ANPEP
ko00770	Pantothenate and CoA biosynthesis	0.714378537698887	-0.336342292285901	17	7	0.00230870712401055	3032	6715	5167,60496,55229,79646,1807,53354,60490	ENPP1,AASDHPPT,PANK4,PANK3,DPYS,PANK1,PPCDC
ko04723	Retrograde endocannabinoid signaling	0.72498710357441	-0.321601412458902	103	44	0.0145118733509235	3032	6715	3763,2566,2565,2782,2570,5578,1432,5566,2783,5331,2890,2793,2568,5601,112,109,51764,5600,779,5330,2771,5567,113,2567,2788,773,107,5613,2786,3710,2554,747,5743,3762,221955,3765,2166,111,114,59345,3708,5332,774,6300	KCNJ6,GABRG2,GABRG1,GNB1,GABRR2,PRKCA,MAPK14,PRKACA,GNB2,PLCB3,GRIA1,GNGT2,GABRP,MAPK9,ADCY6,ADCY3,GNG13,MAPK11,CACNA1S,PLCB2,GNAI2,PRKACB,ADCY7,GABRG3,GNG7,CACNA1A,ADCY1,PRKX,GNG4,ITPR3,GABRA1,DAGLA,PTGS2,KCNJ5,DAGLB,KCNJ9,FAAH,ADCY5,ADCY8,GNB4,ITPR1,PLCB4,CACNA1B,MAPK12
hsa04723	Retrograde endocannabinoid signaling	0.72498710357441	-0.321601412458902	103	44	0.0145118733509235	3032	6715	3763,2566,2565,2782,2570,5578,1432,5566,2783,5331,2890,2793,2568,5601,112,109,51764,5600,779,5330,2771,5567,113,2567,2788,773,107,5613,2786,3710,2554,747,5743,3762,221955,3765,2166,111,114,59345,3708,5332,774,6300	KCNJ6,GABRG2,GABRG1,GNB1,GABRR2,PRKCA,MAPK14,PRKACA,GNB2,PLCB3,GRIA1,GNGT2,GABRP,MAPK9,ADCY6,ADCY3,GNG13,MAPK11,CACNA1S,PLCB2,GNAI2,PRKACB,ADCY7,GABRG3,GNG7,CACNA1A,ADCY1,PRKX,GNG4,ITPR3,GABRA1,DAGLA,PTGS2,KCNJ5,DAGLB,KCNJ9,FAAH,ADCY5,ADCY8,GNB4,ITPR1,PLCB4,CACNA1B,MAPK12
hsa04975	Fat digestion and absorption	0.735541886725257	-0.307147790561885	41	17	0.00560686015831135	3032	6715	4547,8611,10555,346606,1208,29881,8612,84649,10999,1056,80168,81579,949,8694,948,8399,2168	MTTP,PPAP2A,AGPAT2,MOGAT3,CLPS,NPC1L1,PPAP2C,DGAT2,SLC27A4,CEL,MOGAT2,PLA2G12A,SCARB1,DGAT1,CD36,PLA2G10,FABP1
ko04975	Fat digestion and absorption	0.735541886725257	-0.307147790561885	41	17	0.00560686015831135	3032	6715	4547,8611,10555,346606,1208,29881,8612,84649,10999,1056,80168,81579,949,8694,948,8399,2168	MTTP,PPAP2A,AGPAT2,MOGAT3,CLPS,NPC1L1,PPAP2C,DGAT2,SLC27A4,CEL,MOGAT2,PLA2G12A,SCARB1,DGAT1,CD36,PLA2G10,FABP1
hsa_M00351	Spliceosome, U1-snRNP	0.737352672244173	-0.304688977172716	10	4	0.00131926121372032	3032	6715	6635,6632,6625,6628	SNRPE,SNRPD1,SNRNP70,SNRPB
M00351	Spliceosome, U1-snRNP	0.737352672244173	-0.304688977172716	10	4	0.00131926121372032	3032	6715	6635,6632,6625,6628	SNRPE,SNRPD1,SNRNP70,SNRPB
M00296	BER complex	0.737352672244173	-0.304688977172716	10	4	0.00131926121372032	3032	6715	142,3980,143,27343	PARP1,LIG3,PARP4,POLL
M00059	Glycosaminoglycan biosynthesis, heparan sulfate backbone	0.737352672244173	-0.304688977172716	10	4	0.00131926121372032	3032	6715	2131,8509,2134,3340	EXT1,NDST2,EXTL1,NDST1
hsa_M00296	BER complex	0.737352672244173	-0.304688977172716	10	4	0.00131926121372032	3032	6715	142,3980,143,27343	PARP1,LIG3,PARP4,POLL
hsa_M00059	Glycosaminoglycan biosynthesis, heparan sulfate backbone	0.737352672244173	-0.304688977172716	10	4	0.00131926121372032	3032	6715	2131,8509,2134,3340	EXT1,NDST2,EXTL1,NDST1
hsa05416	Viral myocarditis	0.737821354107541	-0.304053551289714	62	26	0.00857519788918206	3032	6715	1604,71,942,6444,8672,54205,857,1982,637,1605,5881,3105,3383,3123,3689,595,25,3113,27,1981,5880,2534,60,3107,5551,940	CD55,ACTG1,CD86,SGCD,EIF4G3,CYCS,CAV1,EIF4G2,BID,DAG1,RAC3,HLA-A,ICAM1,HLA-DRB1,ITGB2,CCND1,ABL1,HLA-DPA1,ABL2,EIF4G1,RAC2,FYN,ACTB,HLA-C,PRF1,CD28
M00340	Proteasome, 20S core particle	0.743369450615319	-0.296562116104725	15	6	0.00197889182058048	3032	6715	5689,5687,5684,5692,5685,5686	PSMB1,PSMA6,PSMA3,PSMB4,PSMA4,PSMA5
hsa_M00340	Proteasome, 20S core particle	0.743369450615319	-0.296562116104725	15	6	0.00197889182058048	3032	6715	5689,5687,5684,5692,5685,5686	PSMB1,PSMA6,PSMA3,PSMB4,PSMA4,PSMA5
M00037	Melatonin biosynthesis, tryptophan => serotonin => melatonin	0.746151969917051	-0.29282598649952	5	2	0.000659630606860158	3032	6715	1644,15	DDC,AANAT
M00405	THC complex	0.746151969917051	-0.29282598649952	5	2	0.000659630606860158	3032	6715	79228,57187	THOC6,THOC2
hsa_M00042	Catecholamine biosynthesis, tyrosine => dopamine => noradrenaline => adrenaline	0.746151969917051	-0.29282598649952	5	2	0.000659630606860158	3032	6715	7299,1644	TYR,DDC
M00289	RF-C complex	0.746151969917051	-0.29282598649952	5	2	0.000659630606860158	3032	6715	5981,5983	RFC1,RFC3
hsa_M00405	THC complex	0.746151969917051	-0.29282598649952	5	2	0.000659630606860158	3032	6715	79228,57187	THOC6,THOC2
hsa_M00386	Cul4-DDB1-CSA complex	0.746151969917051	-0.29282598649952	5	2	0.000659630606860158	3032	6715	9978,1642	RBX1,DDB1
M00386	Cul4-DDB1-CSA complex	0.746151969917051	-0.29282598649952	5	2	0.000659630606860158	3032	6715	9978,1642	RBX1,DDB1
M00042	Catecholamine biosynthesis, tyrosine => dopamine => noradrenaline => adrenaline	0.746151969917051	-0.29282598649952	5	2	0.000659630606860158	3032	6715	7299,1644	TYR,DDC
M00307	Pyruvate oxidation, pyruvate => acetyl-CoA	0.746151969917051	-0.29282598649952	5	2	0.000659630606860158	3032	6715	5161,5160	PDHA2,PDHA1
hsa_M00289	RF-C complex	0.746151969917051	-0.29282598649952	5	2	0.000659630606860158	3032	6715	5981,5983	RFC1,RFC3
hsa_M00037	Melatonin biosynthesis, tryptophan => serotonin => melatonin	0.746151969917051	-0.29282598649952	5	2	0.000659630606860158	3032	6715	1644,15	DDC,AANAT
hsa_M00307	Pyruvate oxidation, pyruvate => acetyl-CoA	0.746151969917051	-0.29282598649952	5	2	0.000659630606860158	3032	6715	5161,5160	PDHA2,PDHA1
hsa_M00049	Adenine ribonucleotide biosynthesis, IMP => ADP,ATP	0.752713888074475	-0.284070086102867	20	8	0.00263852242744063	3032	6715	159,204,29922,5313,8382,5315,122622,4832	ADSS,AK2,NME7,PKLR,NME5,PKM,ADSSL1,NME3
M00049	Adenine ribonucleotide biosynthesis, IMP => ADP,ATP	0.752713888074475	-0.284070086102867	20	8	0.00263852242744063	3032	6715	159,204,29922,5313,8382,5315,122622,4832	ADSS,AK2,NME7,PKLR,NME5,PKM,ADSSL1,NME3
hsa04146	Peroxisome	0.754334102588139	-0.281919902236223	81	34	0.0112137203166227	3032	6715	2180,4598,3418,30,10654,83594,5192,728635,5825,1384,9409,10455,215,1610,5195,11264,84188,51703,5824,189,6647,2181,3295,84769,5052,847,5830,8443,23305,4358,23417,5194,8310,4843	ACSL1,MVK,IDH2,ACAA1,PMVK,NUDT12,PEX10,DHRS4L1,ABCD3,CRAT,PEX16,ECI2,ABCD1,DAO,PEX14,PXMP4,FAR1,ACSL5,PEX19,AGXT,SOD1,ACSL3,HSD17B4,MPV17L2,PRDX1,CAT,PEX5,GNPAT,ACSL6,MPV17,MLYCD,PEX13,ACOX3,NOS2
ko04146	Peroxisome	0.754334102588139	-0.281919902236223	81	34	0.0112137203166227	3032	6715	2180,4598,3418,30,10654,83594,5192,728635,5825,1384,9409,10455,215,1610,5195,11264,84188,51703,5824,189,6647,2181,3295,84769,5052,847,5830,8443,23305,4358,23417,5194,8310,4843	ACSL1,MVK,IDH2,ACAA1,PMVK,NUDT12,PEX10,DHRS4L1,ABCD3,CRAT,PEX16,ECI2,ABCD1,DAO,PEX14,PXMP4,FAR1,ACSL5,PEX19,AGXT,SOD1,ACSL3,HSD17B4,MPV17L2,PRDX1,CAT,PEX5,GNPAT,ACSL6,MPV17,MLYCD,PEX13,ACOX3,NOS2
ko00640	Propanoate metabolism	0.754868061595712	-0.281212297857533	32	13	0.00428759894459103	3032	6715	5096,4329,4594,55902,3939,23417,26275,501,219,84532,224,3945,92483	PCCB,ALDH6A1,MUT,ACSS2,LDHA,MLYCD,HIBCH,ALDH7A1,ALDH1B1,ACSS1,ALDH3A2,LDHB,LDHAL6B
ko03020	RNA polymerase	0.754868061595712	-0.281212297857533	32	13	0.00428759894459103	3032	6715	661,548644,5438,5441,5439,5440,55718,5434,84265,5437,246721,51728,64425	POLR3D,POLR2J3,POLR2I,POLR2L,POLR2J,POLR2K,POLR3E,POLR2E,POLR3GL,POLR2H,POLR2J2,POLR3K,POLR1E
hsa00640	Propanoate metabolism	0.754868061595712	-0.281212297857533	32	13	0.00428759894459103	3032	6715	5096,4329,4594,55902,3939,23417,501,26275,219,84532,224,92483,3945	PCCB,ALDH6A1,MUT,ACSS2,LDHA,MLYCD,ALDH7A1,HIBCH,ALDH1B1,ACSS1,ALDH3A2,LDHAL6B,LDHB
hsa03020	RNA polymerase	0.754868061595712	-0.281212297857533	32	13	0.00428759894459103	3032	6715	661,548644,5438,5441,5439,5440,55718,5434,84265,5437,246721,64425,51728	POLR3D,POLR2J3,POLR2I,POLR2L,POLR2J,POLR2K,POLR3E,POLR2E,POLR3GL,POLR2H,POLR2J2,POLR1E,POLR3K
hsa04978	Mineral absorption	0.761509895512214	-0.272452111968102	51	21	0.00692612137203166	3032	6715	54822,538,4502,795,475,480,94033,65010,115019,481,3162,6523,7421,55630,476,486,6550,340024,7779,477,478	TRPM7,ATP7A,MT2A,S100G,ATOX1,ATP1A4,FTMT,SLC26A6,SLC26A9,ATP1B1,HMOX1,SLC5A1,VDR,SLC39A4,ATP1A1,FXYD2,SLC9A3,SLC6A19,SLC30A1,ATP1A2,ATP1A3
hsa05014	Amyotrophic lateral sclerosis (ALS)	0.761509895512214	-0.272452111968102	51	21	0.00692612137203166	3032	6715	6647,2902,84134,54205,5868,10452,1432,637,5606,79139,847,2890,1616,7132,5533,5600,317,4217,2876,5630,6300	SOD1,GRIN1,TOMM40L,CYCS,RAB5A,TOMM40,MAPK14,BID,MAP2K3,DERL1,CAT,GRIA1,DAXX,TNFRSF1A,PPP3CC,MAPK11,APAF1,MAP3K5,GPX1,PRPH,MAPK12
ko04978	Mineral absorption	0.761509895512214	-0.272452111968102	51	21	0.00692612137203166	3032	6715	54822,538,4502,795,475,480,94033,65010,115019,481,3162,6523,7421,55630,476,486,6550,340024,7779,477,478	TRPM7,ATP7A,MT2A,S100G,ATOX1,ATP1A4,FTMT,SLC26A6,SLC26A9,ATP1B1,HMOX1,SLC5A1,VDR,SLC39A4,ATP1A1,FXYD2,SLC9A3,SLC6A19,SLC30A1,ATP1A2,ATP1A3
ko05014	Amyotrophic lateral sclerosis (ALS)	0.761509895512214	-0.272452111968102	51	21	0.00692612137203166	3032	6715	6647,2902,84134,54205,5868,10452,1432,637,5606,79139,847,2890,1616,7132,5533,5600,317,4217,2876,5630,6300	SOD1,GRIN1,TOMM40L,CYCS,RAB5A,TOMM40,MAPK14,BID,MAP2K3,DERL1,CAT,GRIA1,DAXX,TNFRSF1A,PPP3CC,MAPK11,APAF1,MAP3K5,GPX1,PRPH,MAPK12
hsa00563	Glycosylphosphatidylinositol(GPI)-anchor biosynthesis	0.762842367286319	-0.270703864996585	25	10	0.00329815303430079	3032	6715	5279,93183,51604,9091,54872,8733,5277,94005,5281,55650	PIGC,PIGM,PIGT,PIGQ,PIGG,GPAA1,PIGA,PIGS,PIGF,PIGV
ko00563	Glycosylphosphatidylinositol(GPI)-anchor biosynthesis	0.762842367286319	-0.270703864996585	25	10	0.00329815303430079	3032	6715	5279,93183,51604,9091,54872,8733,5277,94005,5281,55650	PIGC,PIGM,PIGT,PIGQ,PIGG,GPAA1,PIGA,PIGS,PIGF,PIGV
ko04062	Chemokine signaling pathway	0.763049838856418	-0.270431930228791	189	81	0.0267150395778364	3032	6715	5894,6375,2782,2870,6361,4067,5566,1794,2783,25759,5331,7409,1399,6464,53358,3551,4790,5296,5290,8503,109,7074,5567,131890,113,56477,207,2931,2788,57580,107,5613,8517,7454,1233,59345,114,3576,5590,9547,2185,2932,6093,6011,56288,399694,2869,1236,7410,6714,5880,23533,6846,2793,5580,6351,653361,112,3717,51764,6774,2771,5330,5058,10451,5829,6364,5295,2786,3845,5747,9564,2268,111,10000,4792,408,5332,3265,1234,6370	RAF1,XCL1,GNB1,GRK6,CCL17,LYN,PRKACA,DOCK2,GNB2,SHC2,PLCB3,VAV1,CRKL,SHC1,SHC3,IKBKB,NFKB1,PIK3R2,PIK3CA,PIK3R3,ADCY3,TIAM1,PRKACB,GRK7,ADCY7,CCL28,AKT1,GSK3A,GNG7,PREX1,ADCY1,PRKX,IKBKG,WAS,CCR4,GNB4,ADCY8,IL8,PRKCZ,CXCL14,PTK2B,GSK3B,ROCK1,GRK1,PARD3,SHC4,GRK5,CCR7,VAV2,SRC,RAC2,PIK3R5,XCL2,GNGT2,PRKCD,CCL4,NCF1,ADCY6,JAK2,GNG13,STAT3,GNAI2,PLCB2,PAK1,VAV3,PXN,CCL20,PIK3R1,GNG4,KRAS,PTK2,BCAR1,FGR,ADCY5,AKT3,NFKBIA,ARRB1,PLCB4,HRAS,CCR5,CCL25
hsa04062	Chemokine signaling pathway	0.763049838856418	-0.270431930228791	189	81	0.0267150395778364	3032	6715	5894,6375,2782,2870,6361,4067,5566,1794,2783,25759,5331,7409,1399,6464,53358,3551,4790,5296,5290,8503,109,7074,5567,131890,113,56477,207,2931,2788,57580,107,5613,8517,7454,1233,59345,114,3576,5590,9547,2185,2932,6093,6011,56288,399694,2869,1236,7410,6714,5880,23533,6846,2793,5580,6351,653361,112,3717,51764,6774,2771,5330,5058,10451,5829,6364,5295,2786,3845,5747,9564,2268,111,10000,4792,408,5332,3265,1234,6370	RAF1,XCL1,GNB1,GRK6,CCL17,LYN,PRKACA,DOCK2,GNB2,SHC2,PLCB3,VAV1,CRKL,SHC1,SHC3,IKBKB,NFKB1,PIK3R2,PIK3CA,PIK3R3,ADCY3,TIAM1,PRKACB,GRK7,ADCY7,CCL28,AKT1,GSK3A,GNG7,PREX1,ADCY1,PRKX,IKBKG,WAS,CCR4,GNB4,ADCY8,IL8,PRKCZ,CXCL14,PTK2B,GSK3B,ROCK1,GRK1,PARD3,SHC4,GRK5,CCR7,VAV2,SRC,RAC2,PIK3R5,XCL2,GNGT2,PRKCD,CCL4,NCF1,ADCY6,JAK2,GNG13,STAT3,GNAI2,PLCB2,PAK1,VAV3,PXN,CCL20,PIK3R1,GNG4,KRAS,PTK2,BCAR1,FGR,ADCY5,AKT3,NFKBIA,ARRB1,PLCB4,HRAS,CCR5,CCL25
hsa03050	Proteasome	0.763123387738391	-0.270335546829125	44	18	0.00593667546174142	3032	6715	5689,5684,5692,5721,5710,5685,9491,5704,5699,122706,5696,5687,5709,5714,5701,10213,10197,5686	PSMB1,PSMA3,PSMB4,PSME2,PSMD4,PSMA4,PSMF1,PSMC4,PSMB10,PSMB11,PSMB8,PSMA6,PSMD3,PSMD8,PSMC2,PSMD14,PSME3,PSMA5
ko03050	Proteasome	0.763123387738391	-0.270335546829125	44	18	0.00593667546174142	3032	6715	5689,5684,5692,5721,5710,9491,5685,5704,5699,5696,5687,122706,5714,5709,5701,10213,10197,5686	PSMB1,PSMA3,PSMB4,PSME2,PSMD4,PSMF1,PSMA4,PSMC4,PSMB10,PSMB8,PSMA6,PSMB11,PSMD8,PSMD3,PSMC2,PSMD14,PSME3,PSMA5
hsa03450	Non-homologous end-joining	0.775641468688326	-0.254064890451482	13	5	0.0016490765171504	3032	6715	5591,79840,10111,7520,27343	PRKDC,NHEJ1,RAD50,XRCC5,POLL
ko03450	Non-homologous end-joining	0.775641468688326	-0.254064890451482	13	5	0.0016490765171504	3032	6715	79840,5591,10111,7520,27343	NHEJ1,PRKDC,RAD50,XRCC5,POLL
M00430	Exon junction complex (EJC)	0.778422379791628	-0.250485997506651	18	7	0.00230870712401055	3032	6715	5976,29107,5411,10189,10250,9939,10921	UPF1,NXT1,PNN,ALYREF,SRRM1,RBM8A,RNPS1
hsa_M00430	Exon junction complex (EJC)	0.778422379791628	-0.250485997506651	18	7	0.00230870712401055	3032	6715	5976,29107,5411,10189,10250,9939,10921	UPF1,NXT1,PNN,ALYREF,SRRM1,RBM8A,RNPS1
ko05016	Huntington's disease	0.77978372942538	-0.248738667712386	183	78	0.0257255936675462	3032	6715	64764,4712,29796,1346,25942,51079,5331,161,517,7385,7419,4715,4731,7052,1212,4700,4720,10105,6647,1350,5441,27089,90993,514,7416,125965,291,126328,27113,9377,5437,4713,3066,1340,4729,548644,5440,6908,6391,4726,54205,4697,1327,9586,1345,55567,25981,374291,4695,10476,51164,4728,1537,1385,5330,6667,516,148327,5438,2902,23186,9001,6390,5439,160,6874,440567,3708,9167,1351,5434,5332,1211,387332,317,498,246721,2876	CREB3L2,NDUFB6,UQCR10,COX7A1,SIN3A,NDUFA13,PLCB3,AP2A2,ATP5G2,UQCRC2,VDAC3,NDUFB9,NDUFV3,TGM2,CLTB,NDUFA6,NDUFS2,PPIF,SOD1,COX7C,POLR2L,UQCRQ,CREB3L1,ATP5E,VDAC1,COX6B2,SLC25A4,NDUFA11,BBC3,COX5A,POLR2H,NDUFB7,HDAC2,COX6B1,NDUFV2,POLR2J3,POLR2K,TBP,SDHC,NDUFS6,CYCS,NDUFA4,COX4I1,CREB5,COX6C,DNAH3,DNAH1,NDUFS7,NDUFA2,ATP5H,DCTN4,NDUFS8,CYC1,CREB1,PLCB2,SP1,ATP5G1,CREB3L4,POLR2I,GRIN1,RCOR1,HAP1,SDHB,POLR2J,AP2A1,TAF4,UQCRHL,ITPR1,COX7A2L,COX8A,POLR2E,PLCB4,CLTA,TBPL2,APAF1,ATP5A1,POLR2J2,GPX1
hsa05016	Huntington's disease	0.77978372942538	-0.248738667712386	183	78	0.0257255936675462	3032	6715	64764,4712,29796,1346,25942,51079,5331,161,517,7385,7419,4715,4731,7052,1212,4700,4720,10105,6647,1350,5441,27089,90993,514,7416,125965,291,126328,27113,9377,5437,4713,3066,1340,4729,548644,5440,6908,6391,4726,54205,4697,1327,9586,1345,55567,25981,374291,4695,10476,51164,4728,1537,1385,5330,6667,516,148327,5438,2902,23186,9001,6390,5439,160,6874,440567,3708,9167,1351,5434,5332,1211,387332,317,498,246721,2876	CREB3L2,NDUFB6,UQCR10,COX7A1,SIN3A,NDUFA13,PLCB3,AP2A2,ATP5G2,UQCRC2,VDAC3,NDUFB9,NDUFV3,TGM2,CLTB,NDUFA6,NDUFS2,PPIF,SOD1,COX7C,POLR2L,UQCRQ,CREB3L1,ATP5E,VDAC1,COX6B2,SLC25A4,NDUFA11,BBC3,COX5A,POLR2H,NDUFB7,HDAC2,COX6B1,NDUFV2,POLR2J3,POLR2K,TBP,SDHC,NDUFS6,CYCS,NDUFA4,COX4I1,CREB5,COX6C,DNAH3,DNAH1,NDUFS7,NDUFA2,ATP5H,DCTN4,NDUFS8,CYC1,CREB1,PLCB2,SP1,ATP5G1,CREB3L4,POLR2I,GRIN1,RCOR1,HAP1,SDHB,POLR2J,AP2A1,TAF4,UQCRHL,ITPR1,COX7A2L,COX8A,POLR2E,PLCB4,CLTA,TBPL2,APAF1,ATP5A1,POLR2J2,GPX1
hsa03060	Protein export	0.784458842337501	-0.242761171744902	23	9	0.00296833773087071	3032	6715	23478,58477,83943,6726,29927,5018,23480,3309,55176	SEC11A,SRPRB,IMMP2L,SRP9,SEC61A1,OXA1L,SEC61G,HSPA5,SEC61A2
ko03060	Protein export	0.784458842337501	-0.242761171744902	23	9	0.00296833773087071	3032	6715	23478,6726,58477,83943,29927,5018,23480,3309,55176	SEC11A,SRP9,SRPRB,IMMP2L,SEC61A1,OXA1L,SEC61G,HSPA5,SEC61A2
hsa_M00098	Acylglycerol degradation	0.811864526585155	-0.208421791920507	11	4	0.00131926121372032	3032	6715	1056,9388,3990,57104	CEL,LIPG,LIPC,PNPLA2
M00098	Acylglycerol degradation	0.811864526585155	-0.208421791920507	11	4	0.00131926121372032	3032	6715	1056,9388,3990,57104	CEL,LIPG,LIPC,PNPLA2
ko04742	Taste transduction	0.828983559854737	-0.187554955340546	53	21	0.00692612137203166	3032	6715	773,2782,5613,3710,80834,5566,6337,5136,40,114,259287,346562,83756,112,2914,51764,774,6338,5330,29850,5567	CACNA1A,GNB1,PRKX,ITPR3,TAS1R2,PRKACA,SCNN1A,PDE1A,ASIC2,ADCY8,TAS2R41,GNAT3,TAS1R3,ADCY6,GRM4,GNG13,CACNA1B,SCNN1B,PLCB2,TRPM5,PRKACB
hsa04742	Taste transduction	0.828983559854737	-0.187554955340546	53	21	0.00692612137203166	3032	6715	773,2782,5613,3710,80834,5566,6337,5136,40,114,259287,346562,83756,112,2914,51764,774,6338,5330,29850,5567	CACNA1A,GNB1,PRKX,ITPR3,TAS1R2,PRKACA,SCNN1A,PDE1A,ASIC2,ADCY8,TAS2R41,GNAT3,TAS1R3,ADCY6,GRM4,GNG13,CACNA1B,SCNN1B,PLCB2,TRPM5,PRKACB
hsa04650	Natural killer cell mediated cytotoxicity	0.829689984586484	-0.186703160511084	135	56	0.0184696569920844	3032	6715	399694,2207,5894,7410,3937,5578,637,5881,25759,3105,3383,51744,7409,5880,6464,53358,23533,919,9436,5336,5296,5781,5290,8503,3107,5551,80328,6850,22914,3802,80329,5058,27040,10451,79465,6452,3460,5777,5295,8743,4773,3845,1437,3454,4772,5605,2214,355,3689,5335,2534,356,2185,5533,8793,3265	SHC4,FCER1G,RAF1,VAV2,LCP2,PRKCA,BID,RAC3,SHC2,HLA-A,ICAM1,CD244,VAV1,RAC2,SHC1,SHC3,PIK3R5,CD247,NCR2,PLCG2,PIK3R2,PTPN11,PIK3CA,PIK3R3,HLA-C,PRF1,ULBP2,SYK,KLRK1,KIR2DL1,ULBP1,PAK1,LAT,VAV3,ULBP3,SH3BP2,IFNGR2,PTPN6,PIK3R1,TNFSF10,NFATC2,KRAS,CSF2,IFNAR1,NFATC1,MAP2K2,FCGR3A,FAS,ITGB2,PLCG1,FYN,FASLG,PTK2B,PPP3CC,TNFRSF10D,HRAS
ko04650	Natural killer cell mediated cytotoxicity	0.829689984586484	-0.186703160511084	135	56	0.0184696569920844	3032	6715	399694,2207,5894,7410,3937,5578,637,5881,25759,3105,3383,51744,7409,5880,6464,53358,23533,919,9436,5336,5296,5781,5290,8503,3107,5551,80328,6850,22914,3802,80329,5058,27040,10451,79465,6452,3460,5777,5295,8743,4773,3845,1437,3454,4772,5605,2214,355,3689,5335,2534,356,2185,5533,8793,3265	SHC4,FCER1G,RAF1,VAV2,LCP2,PRKCA,BID,RAC3,SHC2,HLA-A,ICAM1,CD244,VAV1,RAC2,SHC1,SHC3,PIK3R5,CD247,NCR2,PLCG2,PIK3R2,PTPN11,PIK3CA,PIK3R3,HLA-C,PRF1,ULBP2,SYK,KLRK1,KIR2DL1,ULBP1,PAK1,LAT,VAV3,ULBP3,SH3BP2,IFNGR2,PTPN6,PIK3R1,TNFSF10,NFATC2,KRAS,CSF2,IFNAR1,NFATC1,MAP2K2,FCGR3A,FAS,ITGB2,PLCG1,FYN,FASLG,PTK2B,PPP3CC,TNFRSF10D,HRAS
ko04320	Dorso-ventral axis formation	0.831261506961653	-0.184810844146499	24	9	0.00296833773087071	3032	6715	4851,2114,9271,3845,4853,2113,56776,64506,1956	NOTCH1,ETS2,PIWIL1,KRAS,NOTCH2,ETS1,FMN2,CPEB1,EGFR
hsa04320	Dorso-ventral axis formation	0.831261506961653	-0.184810844146499	24	9	0.00296833773087071	3032	6715	4851,2114,9271,3845,4853,2113,56776,64506,1956	NOTCH1,ETS2,PIWIL1,KRAS,NOTCH2,ETS1,FMN2,CPEB1,EGFR
M00400	p97-Ufd1-Npl4 complex	0.835067090810033	-0.180243209083542	3	1	0.000329815303430079	3032	6715	7415	VCP
hsa_M00400	p97-Ufd1-Npl4 complex	0.835067090810033	-0.180243209083542	3	1	0.000329815303430079	3032	6715	7415	VCP
hsa_M00069	Glycosphingolipid biosynthesis, ganglio series, LacCer => GT3	0.835067090810033	-0.180243209083542	3	1	0.000329815303430079	3032	6715	6489	ST8SIA1
hsa_M00392	Ski complex	0.835067090810033	-0.180243209083542	3	1	0.000329815303430079	3032	6715	80349	WDR61
M00393	TRAMP complex	0.835067090810033	-0.180243209083542	3	1	0.000329815303430079	3032	6715	11044	PAPD7
M00046	Pyrimidine degradation, uracil => beta-alanine, thymine => 3-aminoisobutanoate	0.835067090810033	-0.180243209083542	3	1	0.000329815303430079	3032	6715	1807	DPYS
M00151	Cytochrome bc1 complex respiratory unit	0.835067090810033	-0.180243209083542	3	1	0.000329815303430079	3032	6715	1537	CYC1
M00392	Ski complex	0.835067090810033	-0.180243209083542	3	1	0.000329815303430079	3032	6715	80349	WDR61
hsa_M00410	ESCRT-II complex	0.835067090810033	-0.180243209083542	3	1	0.000329815303430079	3032	6715	51028	VPS36
hsa_M00151	Cytochrome bc1 complex respiratory unit	0.835067090810033	-0.180243209083542	3	1	0.000329815303430079	3032	6715	1537	CYC1
hsa_M00291	MRN complex	0.835067090810033	-0.180243209083542	3	1	0.000329815303430079	3032	6715	10111	RAD50
hsa_M00393	TRAMP complex	0.835067090810033	-0.180243209083542	3	1	0.000329815303430079	3032	6715	11044	PAPD7
hsa_M00046	Pyrimidine degradation, uracil => beta-alanine, thymine => 3-aminoisobutanoate	0.835067090810033	-0.180243209083542	3	1	0.000329815303430079	3032	6715	1807	DPYS
M00291	MRN complex	0.835067090810033	-0.180243209083542	3	1	0.000329815303430079	3032	6715	10111	RAD50
M00107	Steroid hormone biosynthesis, cholesterol => prognenolone => progesterone	0.835067090810033	-0.180243209083542	3	1	0.000329815303430079	3032	6715	1583	CYP11A1
M00410	ESCRT-II complex	0.835067090810033	-0.180243209083542	3	1	0.000329815303430079	3032	6715	51028	VPS36
hsa_M00107	Steroid hormone biosynthesis, cholesterol => prognenolone => progesterone	0.835067090810033	-0.180243209083542	3	1	0.000329815303430079	3032	6715	1583	CYP11A1
M00069	Glycosphingolipid biosynthesis, ganglio series, LacCer => GT3	0.835067090810033	-0.180243209083542	3	1	0.000329815303430079	3032	6715	6489	ST8SIA1
M00055	N-glycan precursor biosynthesis	0.835943401973691	-0.179194369177659	14	5	0.0016490765171504	3032	6715	85365,29929,79087,144245,84920	ALG2,ALG6,ALG12,ALG10B,ALG10
hsa_M00055	N-glycan precursor biosynthesis	0.835943401973691	-0.179194369177659	14	5	0.0016490765171504	3032	6715	85365,29929,79087,144245,84920	ALG2,ALG6,ALG12,ALG10B,ALG10
hsa_M00090	Phosphatidylcholine (PC) biosynthesis, choline => PC	0.838425804538426	-0.17622918757504	6	2	0.000659630606860158	3032	6715	1120,56994	CHKB,CHPT1
M00013	Malonate semialdehyde pathway, propanoyl-CoA => Acetyl-CoA	0.838425804538426	-0.17622918757504	6	2	0.000659630606860158	3032	6715	26275,4329	HIBCH,ALDH6A1
M00090	Phosphatidylcholine (PC) biosynthesis, choline => PC	0.838425804538426	-0.17622918757504	6	2	0.000659630606860158	3032	6715	1120,56994	CHKB,CHPT1
hsa_M00013	Malonate semialdehyde pathway, propanoyl-CoA => Acetyl-CoA	0.838425804538426	-0.17622918757504	6	2	0.000659630606860158	3032	6715	26275,4329	HIBCH,ALDH6A1
hsa00480	Glutathione metabolism	0.840468554427704	-0.173795739768858	51	20	0.00659630606860158	3032	6715	6723,2678,26873,2878,51056,4259,6241,3418,2687,4953,2950,290,5226,653689,79017,119391,50484,2941,2876,2879	SRM,GGT1,OPLAH,GPX3,LAP3,MGST3,RRM2,IDH2,GGT5,ODC1,GSTP1,ANPEP,PGD,GSTT2B,GGCT,GSTO2,RRM2B,GSTA4,GPX1,GPX4
ko00480	Glutathione metabolism	0.840468554427704	-0.173795739768858	51	20	0.00659630606860158	3032	6715	2678,6723,26873,2878,51056,4259,6241,3418,2687,2950,4953,290,5226,653689,79017,119391,50484,2941,2876,2879	GGT1,SRM,OPLAH,GPX3,LAP3,MGST3,RRM2,IDH2,GGT5,GSTP1,ODC1,ANPEP,PGD,GSTT2B,GGCT,GSTO2,RRM2B,GSTA4,GPX1,GPX4
ko00350	Tyrosine metabolism	0.842181782149201	-0.171759394752575	39	15	0.00494722955145119	3032	6715	221,2954,51409,218,220,4128,7299,1312,2805,7173,81889,55798,1644,222,7306	ALDH3B1,GSTZ1,HEMK1,ALDH3A1,ALDH1A3,MAOA,TYR,COMT,GOT1,TPO,FAHD1,METTL2B,DDC,ALDH3B2,TYRP1
hsa00350	Tyrosine metabolism	0.842181782149201	-0.171759394752575	39	15	0.00494722955145119	3032	6715	221,2954,51409,218,220,4128,7299,2805,1312,7173,81889,55798,1644,7306,222	ALDH3B1,GSTZ1,HEMK1,ALDH3A1,ALDH1A3,MAOA,TYR,GOT1,COMT,TPO,FAHD1,METTL2B,DDC,TYRP1,ALDH3B2
ko05133	Pertussis	0.845798397701581	-0.167474248363158	75	30	0.00989445910290238	3032	6715	718,7189,114548,929,3661,3586,1432,2353,725,713,3689,3725,51806,712,3654,3576,714,4790,5601,3688,163688,5600,3394,2771,722,810,4843,1072,3659,6300	C3,TRAF6,NLRP3,CD14,IRF3,IL10,MAPK14,FOS,C4BPB,C1QB,ITGB2,JUN,CALML5,C1QA,IRAK1,IL8,C1QC,NFKB1,MAPK9,ITGB1,CALML6,MAPK11,IRF8,GNAI2,C4BPA,CALML3,NOS2,CFL1,IRF1,MAPK12
hsa05133	Pertussis	0.845798397701581	-0.167474248363158	75	30	0.00989445910290238	3032	6715	718,7189,114548,929,3661,3586,1432,2353,725,713,3689,3725,51806,712,3654,3576,714,4790,5601,3688,163688,5600,3394,2771,722,810,4843,1072,3659,6300	C3,TRAF6,NLRP3,CD14,IRF3,IL10,MAPK14,FOS,C4BPB,C1QB,ITGB2,JUN,CALML5,C1QA,IRAK1,IL8,C1QC,NFKB1,MAPK9,ITGB1,CALML6,MAPK11,IRF8,GNAI2,C4BPA,CALML3,NOS2,CFL1,IRF1,MAPK12
ko00510	N-Glycan biosynthesis	0.85197144411567	-0.160202269010667	49	19	0.0062664907651715	3032	6715	4248,29929,79087,11253,11282,2683,54344,91869,84920,4122,6184,1650,4245,3703,57171,201595,85365,8703,144245	MGAT3,ALG6,ALG12,MAN1B1,MGAT4B,B4GALT1,DPM3,RFT1,ALG10,MAN2A2,RPN1,DDOST,MGAT1,STT3A,DOLPP1,STT3B,ALG2,B4GALT3,ALG10B
hsa00510	N-Glycan biosynthesis	0.85197144411567	-0.160202269010667	49	19	0.0062664907651715	3032	6715	4248,29929,79087,11282,11253,2683,54344,91869,84920,4122,6184,1650,3703,4245,57171,85365,201595,8703,144245	MGAT3,ALG6,ALG12,MGAT4B,MAN1B1,B4GALT1,DPM3,RFT1,ALG10,MAN2A2,RPN1,DDOST,STT3A,MGAT1,DOLPP1,ALG2,STT3B,B4GALT3,ALG10B
M00009	Citrate cycle (TCA cycle, Krebs cycle)	0.852006166282747	-0.160161514757947	22	8	0.00263852242744063	3032	6715	6390,6391,55753,48,2271,3418,4967,1743	SDHB,SDHC,OGDHL,ACO1,FH,IDH2,OGDH,DLST
hsa_M00009	Citrate cycle (TCA cycle, Krebs cycle)	0.852006166282747	-0.160161514757947	22	8	0.00263852242744063	3032	6715	6390,6391,55753,48,2271,3418,4967,1743	SDHB,SDHC,OGDHL,ACO1,FH,IDH2,OGDH,DLST
hsa00072	Synthesis and degradation of ketone bodies	0.852810377206517	-0.159218057250458	9	3	0.000989445910290238	3032	6715	3157,64064,622	HMGCS1,OXCT2,BDH1
ko00072	Synthesis and degradation of ketone bodies	0.852810377206517	-0.159218057250458	9	3	0.000989445910290238	3032	6715	3157,64064,622	HMGCS1,OXCT2,BDH1
M00158	F-type ATPase, eukaryotes	0.856138502779392	-0.155323113616604	17	6	0.00197889182058048	3032	6715	516,521,514,498,517,10476	ATP5G1,ATP5I,ATP5E,ATP5A1,ATP5G2,ATP5H
ko01210	2-Oxocarboxylic acid metabolism	0.856138502779392	-0.155323113616604	17	6	0.00197889182058048	3032	6715	84706,2805,3418,2875,95,48	GPT2,GOT1,IDH2,GPT,ACY1,ACO1
hsa01210	2-Oxocarboxylic acid metabolism	0.856138502779392	-0.155323113616604	17	6	0.00197889182058048	3032	6715	84706,2805,3418,2875,95,48	GPT2,GOT1,IDH2,GPT,ACY1,ACO1
hsa_M00158	F-type ATPase, eukaryotes	0.856138502779392	-0.155323113616604	17	6	0.00197889182058048	3032	6715	516,521,514,498,517,10476	ATP5G1,ATP5I,ATP5E,ATP5A1,ATP5G2,ATP5H
hsa_M00003	Gluconeogenesis, oxaloacetate => fructose-6P	0.856138502779392	-0.155323113616604	17	6	0.00197889182058048	3032	6715	5224,2597,2023,5230,226,5105	PGAM2,GAPDH,ENO1,PGK1,ALDOA,PCK1
M00003	Gluconeogenesis, oxaloacetate => fructose-6P	0.856138502779392	-0.155323113616604	17	6	0.00197889182058048	3032	6715	5224,2597,2023,5230,226,5105	PGAM2,GAPDH,ENO1,PGK1,ALDOA,PCK1
ko04080	Neuroactive ligand-receptor interaction	0.858383442219865	-0.152704376971134	275	116	0.0382585751978892	3032	6715	5724,5023,4544,5745,552,7067,4923,6344,57105,5732,9002,1241,23566,5645,3352,2859,9340,56923,4157,2642,2899,3362,6754,1146,148,2741,152,1139,2147,53637,2740,8973,1132,3973,2554,3363,2916,59350,5540,3972,1145,56288,5032,7433,9170,55584,11255,4887,3358,2743,1128,1141,2566,2565,2832,23620,5028,2570,136,64106,2492,2688,1815,3274,147,2890,1816,1395,134,1142,2568,5618,706,3952,2587,623,4543,116444,1131,150,5029,2912,2567,6755,3354,2908,5739,9568,2894,1903,2902,10316,8698,154,1135,2913,3360,553,2900,1137,6865,2895,2917,10161,2914,4987,7442,7201,7434,117,5026,2847,3269,1812,6870,5731	PTAFR,P2RX1,MTNR1B,PTH1R,AVPR1A,THRA,NTSR1,SCTR,CYSLTR2,PTGER2,F2RL3,LTB4R,LPAR3,PRSS2,HTR1D,GPR35,GLP2R,NMUR2,MC1R,GCGR,GRIK3,HTR6,SSTR4,CHRNG,ADRA1A,GLRA1,ADRA2C,CHRNA7,F2,S1PR5,GLP1R,CHRNA6,CHRM4,LHCGR,GABRA1,HTR7,GRM6,RXFP1,NPY4R,LHB,CHRNE,PARD3,P2RY11,VIPR1,LPAR2,CHRNA9,HRH3,NPY2R,HTR2C,GLRB,CHRM1,CHRNB2,GABRG2,GABRG1,NPBWR2,NTSR2,P2RY1,GABRR2,ADORA2B,NPFFR1,FSHR,GH1,DRD4,HRH2,ADRA1B,GRIA1,DRD5,CRHR2,ADORA1,CHRNB3,GABRP,PRLR,TSPO,LEP,GALR1,BDKRB1,MTNR1A,GRIN3B,CHRM3,ADRA2A,P2RY2,GRM2,GABRG3,SSTR5,HTR1E,NR3C1,PTGIR,GABBR2,GRID1,S1PR3,GRIN1,NMUR1,S1PR4,ADRB2,CHRNA2,GRM3,HTR4,AVPR1B,GRIK4,CHRNA4,TACR2,GRID2,GRM7,LPAR6,GRM4,OPRL1,TRPV1,TRHR,VIPR2,ADCYAP1R1,P2RX5,MCHR1,HRH1,DRD1,TACR3,PTGER1
hsa04080	Neuroactive ligand-receptor interaction	0.858383442219865	-0.152704376971134	275	116	0.0382585751978892	3032	6715	5724,5023,4544,5745,552,7067,4923,6344,57105,5732,9002,1241,23566,5645,3352,2859,9340,56923,4157,2642,2899,3362,6754,1146,148,2741,152,1139,2147,53637,2740,8973,1132,3973,2554,3363,2916,59350,5540,3972,1145,56288,5032,7433,9170,55584,11255,4887,3358,2743,1128,1141,2566,2565,2832,23620,5028,2570,136,64106,2492,2688,1815,3274,147,2890,1816,1395,134,1142,2568,5618,706,3952,2587,623,4543,116444,1131,150,5029,2912,2567,6755,3354,2908,5739,9568,2894,1903,2902,10316,8698,154,1135,2913,3360,553,2900,1137,6865,2895,2917,10161,2914,4987,7442,7201,7434,117,5026,2847,3269,1812,6870,5731	PTAFR,P2RX1,MTNR1B,PTH1R,AVPR1A,THRA,NTSR1,SCTR,CYSLTR2,PTGER2,F2RL3,LTB4R,LPAR3,PRSS2,HTR1D,GPR35,GLP2R,NMUR2,MC1R,GCGR,GRIK3,HTR6,SSTR4,CHRNG,ADRA1A,GLRA1,ADRA2C,CHRNA7,F2,S1PR5,GLP1R,CHRNA6,CHRM4,LHCGR,GABRA1,HTR7,GRM6,RXFP1,NPY4R,LHB,CHRNE,PARD3,P2RY11,VIPR1,LPAR2,CHRNA9,HRH3,NPY2R,HTR2C,GLRB,CHRM1,CHRNB2,GABRG2,GABRG1,NPBWR2,NTSR2,P2RY1,GABRR2,ADORA2B,NPFFR1,FSHR,GH1,DRD4,HRH2,ADRA1B,GRIA1,DRD5,CRHR2,ADORA1,CHRNB3,GABRP,PRLR,TSPO,LEP,GALR1,BDKRB1,MTNR1A,GRIN3B,CHRM3,ADRA2A,P2RY2,GRM2,GABRG3,SSTR5,HTR1E,NR3C1,PTGIR,GABBR2,GRID1,S1PR3,GRIN1,NMUR1,S1PR4,ADRB2,CHRNA2,GRM3,HTR4,AVPR1B,GRIK4,CHRNA4,TACR2,GRID2,GRM7,LPAR6,GRM4,OPRL1,TRPV1,TRHR,VIPR2,ADCYAP1R1,P2RX5,MCHR1,HRH1,DRD1,TACR3,PTGER1
hsa00590	Arachidonic acid metabolism	0.866757478988124	-0.14299606568224	64	25	0.00824538258575198	3032	6715	5321,2678,127281,2878,6916,81579,2687,151056,8399,100137049,240,283748,5743,8605,873,4056,255189,5740,5730,5742,4048,2876,9536,8398,123745	PLA2G4A,GGT1,FAM213B,GPX3,TBXAS1,PLA2G12A,GGT5,PLB1,PLA2G10,PLA2G4B,ALOX5,PLA2G4D,PTGS2,PLA2G4C,CBR1,LTC4S,PLA2G4F,PTGIS,PTGDS,PTGS1,LTA4H,GPX1,PTGES,PLA2G6,PLA2G4E
hsa04623	Cytosolic DNA-sensing pathway	0.866757478988124	-0.14299606568224	64	25	0.00824538258575198	3032	6715	29110,5441,5440,84265,8737,11277,3606,3661,51728,8517,661,9641,9447,3551,6351,55718,4790,4792,5434,3665,103,5437,57506,81030,340061	TBK1,POLR2L,POLR2K,POLR3GL,RIPK1,TREX1,IL18,IRF3,POLR3K,IKBKG,POLR3D,IKBKE,AIM2,IKBKB,CCL4,POLR3E,NFKB1,NFKBIA,POLR2E,IRF7,ADAR,POLR2H,MAVS,ZBP1,TMEM173
ko04623	Cytosolic DNA-sensing pathway	0.866757478988124	-0.14299606568224	64	25	0.00824538258575198	3032	6715	29110,5441,5440,84265,8737,11277,3606,3661,51728,8517,661,9641,9447,3551,6351,55718,4790,4792,5434,3665,103,5437,57506,81030,340061	TBK1,POLR2L,POLR2K,POLR3GL,RIPK1,TREX1,IL18,IRF3,POLR3K,IKBKG,POLR3D,IKBKE,AIM2,IKBKB,CCL4,POLR3E,NFKB1,NFKBIA,POLR2E,IRF7,ADAR,POLR2H,MAVS,ZBP1,TMEM173
ko00590	Arachidonic acid metabolism	0.866757478988124	-0.14299606568224	64	25	0.00824538258575198	3032	6715	5321,2678,127281,2878,6916,81579,2687,151056,8399,100137049,283748,240,5743,8605,873,4056,255189,5730,5740,5742,4048,2876,9536,8398,123745	PLA2G4A,GGT1,FAM213B,GPX3,TBXAS1,PLA2G12A,GGT5,PLB1,PLA2G10,PLA2G4B,PLA2G4D,ALOX5,PTGS2,PLA2G4C,CBR1,LTC4S,PLA2G4F,PTGDS,PTGIS,PTGS1,LTA4H,GPX1,PTGES,PLA2G6,PLA2G4E
M00087	beta-Oxidation	0.868042952570282	-0.141514081018131	12	4	0.00131926121372032	3032	6715	3033,30,37,8310	HADH,ACAA1,ACADVL,ACOX3
hsa_M00052	Pyrimidine ribonucleotide biosynthesis, UMP => UDP/UTP,CDP/CTP	0.868042952570282	-0.141514081018131	12	4	0.00131926121372032	3032	6715	29922,4832,8382,1503	NME7,NME3,NME5,CTPS1
M00052	Pyrimidine ribonucleotide biosynthesis, UMP => UDP/UTP,CDP/CTP	0.868042952570282	-0.141514081018131	12	4	0.00131926121372032	3032	6715	29922,4832,8382,1503	NME7,NME3,NME5,CTPS1
hsa_M00087	beta-Oxidation	0.868042952570282	-0.141514081018131	12	4	0.00131926121372032	3032	6715	3033,30,37,8310	HADH,ACAA1,ACADVL,ACOX3
ko05033	Nicotine addiction	0.872221717520533	-0.136711624180949	40	15	0.00494722955145119	3032	6715	2554,1139,2890,1137,2568,773,1141,2902,2566,8973,2565,2570,774,116444,2567	GABRA1,CHRNA7,GRIA1,CHRNA4,GABRP,CACNA1A,CHRNB2,GRIN1,GABRG2,CHRNA6,GABRG1,GABRR2,CACNA1B,GRIN3B,GABRG3
hsa05033	Nicotine addiction	0.872221717520533	-0.136711624180949	40	15	0.00494722955145119	3032	6715	2554,1139,2890,1137,2568,773,1141,2902,2566,8973,2565,2570,774,116444,2567	GABRA1,CHRNA7,GRIA1,CHRNA4,GABRP,CACNA1A,CHRNB2,GRIN1,GABRG2,CHRNA6,GABRG1,GABRR2,CACNA1B,GRIN3B,GABRG3
ko03040	Spliceosome	0.881089794768415	-0.126595734552633	131	53	0.0174802110817942	3032	6715	3178,6627,25949,10523,26121,56949,6431,9939,1659,25804,6635,139804,3303,220988,83443,10992,151903,6427,6632,56259,84844,10189,55696,6434,9716,3192,3306,55660,6628,3312,51639,3183,9129,10907,10915,8175,3304,6426,22827,3310,9879,10262,11157,10569,57187,22916,9128,1655,6625,494115,9785,10285,84321	HNRNPA1,SNRPA1,SYF2,CHERP,PRPF31,XAB2,SRSF6,RBM8A,DHX8,LSM4,SNRPE,RBMXL3,HSPA1A,HNRNPA3,SF3B5,SF3B2,CCDC12,SRSF2,SNRPD1,CTNNBL1,PHF5A,ALYREF,RBM22,TRA2B,AQR,HNRNPU,HSPA2,PRPF40A,SNRPB,HSPA8,SF3B14,HNRNPC,PRPF3,TXNL4A,TCERG1,SF3A2,HSPA1B,SRSF1,PUF60,HSPA6,DDX46,SF3B4,LSM6,SLU7,THOC2,NCBP2,PRPF4,DDX5,SNRNP70,RBMXL1,DHX38,SMNDC1,THOC3
hsa03040	Spliceosome	0.881089794768415	-0.126595734552633	131	53	0.0174802110817942	3032	6715	3178,6627,25949,10523,26121,56949,6431,9939,1659,25804,6635,139804,3303,220988,83443,10992,151903,6427,6632,56259,84844,10189,55696,6434,9716,3192,3306,55660,6628,3312,51639,3183,9129,10907,10915,8175,3304,6426,22827,3310,9879,10262,11157,10569,57187,22916,9128,1655,6625,494115,9785,10285,84321	HNRNPA1,SNRPA1,SYF2,CHERP,PRPF31,XAB2,SRSF6,RBM8A,DHX8,LSM4,SNRPE,RBMXL3,HSPA1A,HNRNPA3,SF3B5,SF3B2,CCDC12,SRSF2,SNRPD1,CTNNBL1,PHF5A,ALYREF,RBM22,TRA2B,AQR,HNRNPU,HSPA2,PRPF40A,SNRPB,HSPA8,SF3B14,HNRNPC,PRPF3,TXNL4A,TCERG1,SF3A2,HSPA1B,SRSF1,PUF60,HSPA6,DDX46,SF3B4,LSM6,SLU7,THOC2,NCBP2,PRPF4,DDX5,SNRNP70,RBMXL1,DHX38,SMNDC1,THOC3
hsa_M00146	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex	0.882230377643992	-0.125302057939054	15	5	0.0016490765171504	3032	6715	4697,4700,4695,51079,126328	NDUFA4,NDUFA6,NDUFA2,NDUFA13,NDUFA11
M00146	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex	0.882230377643992	-0.125302057939054	15	5	0.0016490765171504	3032	6715	4697,4700,4695,51079,126328	NDUFA4,NDUFA6,NDUFA2,NDUFA13,NDUFA11
M00075	N-glycan biosynthesis, complex type	0.882230377643992	-0.125302057939054	15	5	0.0016490765171504	3032	6715	4122,4248,2683,8703,11282	MAN2A2,MGAT3,B4GALT1,B4GALT3,MGAT4B
hsa_M00075	N-glycan biosynthesis, complex type	0.882230377643992	-0.125302057939054	15	5	0.0016490765171504	3032	6715	4122,4248,2683,8703,11282	MAN2A2,MGAT3,B4GALT1,B4GALT3,MGAT4B
ko05206	MicroRNAs in cancer	0.8875740102727	-0.119263369252911	296	124	0.0408970976253298	3032	6715	9134,1591,407010,406970,1788,2475,6768,406969,5894,407026,7148,4194,2064,324,1026,406957,7329,5578,3162,3925,407006,898,406938,5154,595,1399,57521,8651,6464,3551,5336,4790,5296,406971,407046,5290,6935,4082,994,4233,5159,407017,406881,578,442891,100500809,406997,406909,406991,1871,7431,4170,672,693187,7422,995,406984,406992,5743,5335,9759,6093,7168,1870,27250,9839,4318,8091,90427,399694,407033,406917,11186,9493,4853,7042,27086,9252,10298,407025,54541,25,2261,406923,406935,4609,406985,5962,63923,5292,2065,960,89780,6774,85414,406911,10253,407015,993,4851,7143,1944,406925,3845,900,406913,23414,407007,5605,406937,1956,406976,442910,6624,113130,23405,406986,472,406884,406988,442900,3265,406883,406955	CCNE2,CYP24A1,MIR23A,MIR194-2,DNMT3A,MTOR,ST14,MIR194-1,RAF1,MIR29C,TNXB,MDM4,ERBB2,APC,CDKN1A,MIR181C,UBE2I,PRKCA,HMOX1,STMN1,MIR221,CCNE1,MIR146A,PDGFA,CCND1,CRKL,RPTOR,SOCS1,SHC1,IKBKB,PLCG2,NFKB1,PIK3R2,MIR195,MIR9-1,PIK3CA,ZEB1,MARCKS,CDC25B,MET,PDGFRB,MIR26B,MIRLET7A1,BAK1,MIR135B,MIR23C,MIR215,MIR124-3,MIR21,E2F3,VIM,MCL1,BRCA1,MIR602,VEGFA,CDC25C,MIR200B,MIR210,PTGS2,PLCG1,HDAC4,ROCK1,TPM1,E2F2,PDCD4,ZEB2,MMP9,HMGA2,BMF,SHC4,MIR30D,MIR129-1,RASSF1,KIF23,NOTCH2,TGFB2,FOXP1,RPS6KA5,PAK4,MIR29B2,DDIT4,ABL1,FGFR3,MIR133A2,MIR143,MYC,MIR200C,RDX,TNN,PIM1,ERBB3,CD44,WNT3A,STAT3,SLC45A3,MIR125B1,SPRY2,MIR26A1,CDC25A,NOTCH1,TNR,EFNA3,MIR135A1,KRAS,CCNG1,MIR126,ZFPM2,MIR222,MAP2K2,MIR145,EGFR,MIR199A1,MIR345,FSCN1,CDCA5,DICER1,MIR203,ATM,MIRLET7B,MIR205,MIR326,HRAS,MIRLET7A3,MIR181B1
hsa05206	MicroRNAs in cancer	0.8875740102727	-0.119263369252911	296	124	0.0408970976253298	3032	6715	9134,1591,407010,406970,1788,2475,6768,406969,5894,407026,7148,4194,2064,324,1026,406957,7329,5578,3162,3925,407006,898,406938,5154,595,1399,57521,8651,6464,3551,5336,4790,5296,406971,407046,5290,6935,4082,994,4233,5159,407017,406881,578,442891,100500809,406997,406909,406991,1871,7431,4170,672,693187,7422,995,406984,406992,5743,5335,9759,6093,7168,1870,27250,9839,4318,8091,90427,399694,407033,406917,11186,9493,4853,7042,27086,9252,10298,407025,54541,25,2261,406923,406935,4609,406985,5962,63923,5292,2065,960,89780,6774,85414,406911,10253,407015,993,4851,7143,1944,406925,3845,900,406913,23414,407007,5605,406937,1956,406976,442910,6624,113130,23405,406986,472,406884,406988,442900,3265,406883,406955	CCNE2,CYP24A1,MIR23A,MIR194-2,DNMT3A,MTOR,ST14,MIR194-1,RAF1,MIR29C,TNXB,MDM4,ERBB2,APC,CDKN1A,MIR181C,UBE2I,PRKCA,HMOX1,STMN1,MIR221,CCNE1,MIR146A,PDGFA,CCND1,CRKL,RPTOR,SOCS1,SHC1,IKBKB,PLCG2,NFKB1,PIK3R2,MIR195,MIR9-1,PIK3CA,ZEB1,MARCKS,CDC25B,MET,PDGFRB,MIR26B,MIRLET7A1,BAK1,MIR135B,MIR23C,MIR215,MIR124-3,MIR21,E2F3,VIM,MCL1,BRCA1,MIR602,VEGFA,CDC25C,MIR200B,MIR210,PTGS2,PLCG1,HDAC4,ROCK1,TPM1,E2F2,PDCD4,ZEB2,MMP9,HMGA2,BMF,SHC4,MIR30D,MIR129-1,RASSF1,KIF23,NOTCH2,TGFB2,FOXP1,RPS6KA5,PAK4,MIR29B2,DDIT4,ABL1,FGFR3,MIR133A2,MIR143,MYC,MIR200C,RDX,TNN,PIM1,ERBB3,CD44,WNT3A,STAT3,SLC45A3,MIR125B1,SPRY2,MIR26A1,CDC25A,NOTCH1,TNR,EFNA3,MIR135A1,KRAS,CCNG1,MIR126,ZFPM2,MIR222,MAP2K2,MIR145,EGFR,MIR199A1,MIR345,FSCN1,CDCA5,DICER1,MIR203,ATM,MIRLET7B,MIR205,MIR326,HRAS,MIRLET7A3,MIR181B1
M00341	Proteasome, 19S regulatory particle (PA700)	0.894996564273901	-0.110935399514761	18	6	0.00197889182058048	3032	6715	5710,5709,5714,5701,5704,10213	PSMD4,PSMD3,PSMD8,PSMC2,PSMC4,PSMD14
hsa_M00341	Proteasome, 19S regulatory particle (PA700)	0.894996564273901	-0.110935399514761	18	6	0.00197889182058048	3032	6715	5710,5709,5714,5701,5704,10213	PSMD4,PSMD3,PSMD8,PSMC2,PSMC4,PSMD14
hsa05164	Influenza A	0.89775777043126	-0.107854990462264	179	73	0.0240765171503958	3032	6715	71,114548,10625,79671,5894,5611,9451,3606,3661,5578,1432,3303,5645,5606,3113,7706,3551,4790,5296,5290,8503,103,57506,1386,3306,84000,4599,29107,207,3312,8743,11100,7416,7297,9021,3310,7514,3576,7132,2932,3665,60,6041,8793,8106,6300,54205,3383,3123,3725,23533,5601,10379,3717,5600,10898,29110,3460,5609,5295,5045,27102,3454,5605,390748,4261,3304,355,9641,10000,4792,2224,356	ACTG1,NLRP3,IVNS1ABP,NLRX1,RAF1,DNAJC3,EIF2AK3,IL18,IRF3,PRKCA,MAPK14,HSPA1A,PRSS2,MAP2K3,HLA-DPA1,TRIM25,IKBKB,NFKB1,PIK3R2,PIK3CA,PIK3R3,ADAR,MAVS,ATF2,HSPA2,TMPRSS13,MX1,NXT1,AKT1,HSPA8,TNFSF10,HNRNPUL1,VDAC1,TYK2,SOCS3,HSPA6,XPO1,IL8,TNFRSF1A,GSK3B,IRF7,ACTB,RNASEL,TNFRSF10D,PABPN1,MAPK12,CYCS,ICAM1,HLA-DRB1,JUN,PIK3R5,MAPK9,IRF9,JAK2,MAPK11,CPSF4,TBK1,IFNGR2,MAP2K7,PIK3R1,FURIN,EIF2AK1,IFNAR1,MAP2K2,PABPN1L,CIITA,HSPA1B,FAS,IKBKE,AKT3,NFKBIA,FDPS,FASLG
ko05164	Influenza A	0.89775777043126	-0.107854990462264	179	73	0.0240765171503958	3032	6715	71,114548,10625,79671,5894,5611,9451,3606,3661,5578,1432,3303,5645,5606,3113,7706,3551,4790,5296,5290,8503,103,57506,1386,3306,84000,4599,29107,207,3312,8743,11100,7416,7297,9021,3310,7514,3576,7132,2932,3665,60,6041,8793,8106,6300,54205,3383,3123,3725,23533,5601,10379,3717,5600,10898,29110,3460,5609,5295,5045,27102,3454,5605,390748,4261,3304,355,9641,10000,4792,2224,356	ACTG1,NLRP3,IVNS1ABP,NLRX1,RAF1,DNAJC3,EIF2AK3,IL18,IRF3,PRKCA,MAPK14,HSPA1A,PRSS2,MAP2K3,HLA-DPA1,TRIM25,IKBKB,NFKB1,PIK3R2,PIK3CA,PIK3R3,ADAR,MAVS,ATF2,HSPA2,TMPRSS13,MX1,NXT1,AKT1,HSPA8,TNFSF10,HNRNPUL1,VDAC1,TYK2,SOCS3,HSPA6,XPO1,IL8,TNFRSF1A,GSK3B,IRF7,ACTB,RNASEL,TNFRSF10D,PABPN1,MAPK12,CYCS,ICAM1,HLA-DRB1,JUN,PIK3R5,MAPK9,IRF9,JAK2,MAPK11,CPSF4,TBK1,IFNGR2,MAP2K7,PIK3R1,FURIN,EIF2AK1,IFNAR1,MAP2K2,PABPN1L,CIITA,HSPA1B,FAS,IKBKE,AKT3,NFKBIA,FDPS,FASLG
hsa_M00396	Lsm 2-8 complex	0.899145811248679	-0.106310064949676	7	2	0.000659630606860158	3032	6715	25804,11157	LSM4,LSM6
M00396	Lsm 2-8 complex	0.899145811248679	-0.106310064949676	7	2	0.000659630606860158	3032	6715	25804,11157	LSM4,LSM6
hsa00430	Taurine and hypotaurine metabolism	0.902292250774843	-0.102816808320853	10	3	0.000989445910290238	3032	6715	51380,2678,2687	CSAD,GGT1,GGT5
ko00430	Taurine and hypotaurine metabolism	0.902292250774843	-0.102816808320853	10	3	0.000989445910290238	3032	6715	51380,2678,2687	CSAD,GGT1,GGT5
ko03018	RNA degradation	0.902347129709565	-0.102755988485785	73	28	0.00923482849604222	3032	6715	80349,23019,11044,7832,9337,25804,5073,219988,9924,4849,167227,5042,131870,10950,694,3313,25904,11157,10766,56915,55802,57472,54512,27257,2023,10140,87178,26986	WDR61,CNOT1,PAPD7,BTG2,CNOT8,LSM4,PARN,PATL1,PAN2,CNOT3,DCP2,PABPC3,NUDT16,BTG3,BTG1,HSPA9,CNOT10,LSM6,TOB2,EXOSC5,DCP1A,CNOT6,EXOSC4,LSM1,ENO1,TOB1,PNPT1,PABPC1
hsa03018	RNA degradation	0.902347129709565	-0.102755988485785	73	28	0.00923482849604222	3032	6715	80349,23019,11044,7832,9337,25804,5073,219988,9924,4849,167227,5042,131870,10950,694,3313,25904,11157,10766,56915,55802,57472,54512,27257,2023,10140,87178,26986	WDR61,CNOT1,PAPD7,BTG2,CNOT8,LSM4,PARN,PATL1,PAN2,CNOT3,DCP2,PABPC3,NUDT16,BTG3,BTG1,HSPA9,CNOT10,LSM6,TOB2,EXOSC5,DCP1A,CNOT6,EXOSC4,LSM1,ENO1,TOB1,PNPT1,PABPC1
ko01040	Biosynthesis of unsaturated fatty acids	0.90635258120577	-0.0983268861644597	21	7	0.00230870712401055	3032	6715	60481,9415,30,8310,79071,11332,51144	ELOVL5,FADS2,ACAA1,ACOX3,ELOVL6,ACOT7,HSD17B12
hsa01040	Biosynthesis of unsaturated fatty acids	0.90635258120577	-0.0983268861644597	21	7	0.00230870712401055	3032	6715	60481,9415,30,8310,79071,51144,11332	ELOVL5,FADS2,ACAA1,ACOX3,ELOVL6,HSD17B12,ACOT7
hsa00190	Oxidative phosphorylation	0.908576531817689	-0.0958761549385816	133	53	0.0174802110817942	3032	6715	4729,4712,6391,29796,1346,4726,537,90423,1327,521,495,4697,1345,51079,1352,525,374291,533,4695,517,10476,7385,4728,4715,4731,1537,51606,4700,9114,4720,496,9550,516,1350,27089,514,64077,6390,125965,10312,440567,126328,9167,1351,127124,27068,9377,527,498,528,4713,8992,1340	NDUFV2,NDUFB6,SDHC,UQCR10,COX7A1,NDUFS6,ATP6AP1,ATP6V1E2,COX4I1,ATP5I,ATP4A,NDUFA4,COX6C,NDUFA13,COX10,ATP6V1B1,NDUFS7,ATP6V0B,NDUFA2,ATP5G2,ATP5H,UQCRC2,NDUFS8,NDUFB9,NDUFV3,CYC1,ATP6V1H,NDUFA6,ATP6V0D1,NDUFS2,ATP4B,ATP6V1G1,ATP5G1,COX7C,UQCRQ,ATP5E,LHPP,SDHB,COX6B2,TCIRG1,UQCRHL,NDUFA11,COX7A2L,COX8A,ATP6V1G3,PPA2,COX5A,ATP6V0C,ATP5A1,ATP6V1C1,NDUFB7,ATP6V0E1,COX6B1
ko00190	Oxidative phosphorylation	0.908576531817689	-0.0958761549385816	133	53	0.0174802110817942	3032	6715	4729,4712,6391,1346,29796,4726,537,90423,521,495,1327,4697,1345,51079,1352,374291,525,533,4695,517,10476,7385,4728,4731,4715,1537,51606,4700,496,9114,4720,9550,516,1350,27089,514,64077,6390,125965,10312,440567,126328,9167,127124,1351,27068,9377,527,498,528,4713,8992,1340	NDUFV2,NDUFB6,SDHC,COX7A1,UQCR10,NDUFS6,ATP6AP1,ATP6V1E2,ATP5I,ATP4A,COX4I1,NDUFA4,COX6C,NDUFA13,COX10,NDUFS7,ATP6V1B1,ATP6V0B,NDUFA2,ATP5G2,ATP5H,UQCRC2,NDUFS8,NDUFV3,NDUFB9,CYC1,ATP6V1H,NDUFA6,ATP4B,ATP6V0D1,NDUFS2,ATP6V1G1,ATP5G1,COX7C,UQCRQ,ATP5E,LHPP,SDHB,COX6B2,TCIRG1,UQCRHL,NDUFA11,COX7A2L,ATP6V1G3,COX8A,PPA2,COX5A,ATP6V0C,ATP5A1,ATP6V1C1,NDUFB7,ATP6V0E1,COX6B1
hsa00280	Valine, leucine and isoleucine degradation	0.908743467657731	-0.0956924384323413	44	16	0.00527704485488127	3032	6715	35,5096,3157,3033,4329,4594,64064,594,56922,501,26275,219,30,224,64087,11112	ACADS,PCCB,HMGCS1,HADH,ALDH6A1,MUT,OXCT2,BCKDHB,MCCC1,ALDH7A1,HIBCH,ALDH1B1,ACAA1,ALDH3A2,MCCC2,HIBADH
ko00280	Valine, leucine and isoleucine degradation	0.908743467657731	-0.0956924384323413	44	16	0.00527704485488127	3032	6715	35,5096,4329,4594,594,56922,219,30,3157,3033,64064,26275,501,224,64087,11112	ACADS,PCCB,ALDH6A1,MUT,BCKDHB,MCCC1,ALDH1B1,ACAA1,HMGCS1,HADH,OXCT2,HIBCH,ALDH7A1,ALDH3A2,MCCC2,HIBADH
hsa_M00263	DNA polymerase epsilon complex	0.909571944896618	-0.094781180362925	4	1	0.000329815303430079	3032	6715	5426	POLE
M00261	DNA polymerase alpha / primase complex	0.909571944896618	-0.094781180362925	4	1	0.000329815303430079	3032	6715	5558	PRIM2
M00110	C19/C18-Steroid hormone biosynthesis, pregnenolone => androstenedione => estrone	0.909571944896618	-0.094781180362925	4	1	0.000329815303430079	3032	6715	1588	CYP19A1
ko00471	D-Glutamine and D-glutamate metabolism	0.909571944896618	-0.094781180362925	4	1	0.000329815303430079	3032	6715	2747	GLUD2
hsa_M00261	DNA polymerase alpha / primase complex	0.909571944896618	-0.094781180362925	4	1	0.000329815303430079	3032	6715	5558	PRIM2
M00070	Glycosphingolipid biosynthesis, lacto-series, LacCer => Lc4Cer	0.909571944896618	-0.094781180362925	4	1	0.000329815303430079	3032	6715	8707	B3GALT2
hsa00471	D-Glutamine and D-glutamate metabolism	0.909571944896618	-0.094781180362925	4	1	0.000329815303430079	3032	6715	2747	GLUD2
hsa_M00070	Glycosphingolipid biosynthesis, lacto-series, LacCer => Lc4Cer	0.909571944896618	-0.094781180362925	4	1	0.000329815303430079	3032	6715	8707	B3GALT2
M00263	DNA polymerase epsilon complex	0.909571944896618	-0.094781180362925	4	1	0.000329815303430079	3032	6715	5426	POLE
hsa_M00390	Exosome, archaea	0.909571944896618	-0.094781180362925	4	1	0.000329815303430079	3032	6715	54512	EXOSC4
hsa_M00110	C19/C18-Steroid hormone biosynthesis, pregnenolone => androstenedione => estrone	0.909571944896618	-0.094781180362925	4	1	0.000329815303430079	3032	6715	1588	CYP19A1
M00390	Exosome, archaea	0.909571944896618	-0.094781180362925	4	1	0.000329815303430079	3032	6715	54512	EXOSC4
hsa00591	Linoleic acid metabolism	0.911851977194185	-0.0922776077889326	29	10	0.00329815303430079	3032	6715	283748,5321,8605,255189,81579,151056,8398,8399,100137049,123745	PLA2G4D,PLA2G4A,PLA2G4C,PLA2G4F,PLA2G12A,PLB1,PLA2G6,PLA2G10,PLA2G4B,PLA2G4E
ko00591	Linoleic acid metabolism	0.911851977194185	-0.0922776077889326	29	10	0.00329815303430079	3032	6715	283748,5321,8605,255189,81579,151056,8398,8399,100137049,123745	PLA2G4D,PLA2G4A,PLA2G4C,PLA2G4F,PLA2G12A,PLB1,PLA2G6,PLA2G10,PLA2G4B,PLA2G4E
ko05321	Inflammatory bowel disease (IBD)	0.916231366161634	-0.0874863630558701	69	26	0.00857519788918206	3032	6715	6097,3460,6775,3596,3565,2625,3606,3586,7042,4772,50615,6095,3123,4088,3113,3725,4087,6778,4790,64127,30009,3566,6774,4094,7100,3567	RORC,IFNGR2,STAT4,IL13,IL4,GATA3,IL18,IL10,TGFB2,NFATC1,IL21R,RORA,HLA-DRB1,SMAD3,HLA-DPA1,JUN,SMAD2,STAT6,NFKB1,NOD2,TBX21,IL4R,STAT3,MAF,TLR5,IL5
hsa05321	Inflammatory bowel disease (IBD)	0.916231366161634	-0.0874863630558701	69	26	0.00857519788918206	3032	6715	6097,3460,6775,3596,3565,2625,3606,3586,7042,4772,50615,6095,3123,4088,3113,3725,4087,6778,4790,64127,30009,3566,6774,4094,7100,3567	RORC,IFNGR2,STAT4,IL13,IL4,GATA3,IL18,IL10,TGFB2,NFATC1,IL21R,RORA,HLA-DRB1,SMAD3,HLA-DPA1,JUN,SMAD2,STAT6,NFKB1,NOD2,TBX21,IL4R,STAT3,MAF,TLR5,IL5
hsa_M00355	Spliceosome, 35S U5-snRNP	0.919486411770091	-0.0839400128935118	37	13	0.00428759894459103	3032	6715	151903,6632,25949,56949,6628,55696,3312,6635,9716,3306,3303,3304,3310	CCDC12,SNRPD1,SYF2,XAB2,SNRPB,RBM22,HSPA8,SNRPE,AQR,HSPA2,HSPA1A,HSPA1B,HSPA6
M00355	Spliceosome, 35S U5-snRNP	0.919486411770091	-0.0839400128935118	37	13	0.00428759894459103	3032	6715	151903,6632,25949,56949,6628,55696,3312,6635,9716,3306,3303,3304,3310	CCDC12,SNRPD1,SYF2,XAB2,SNRPB,RBM22,HSPA8,SNRPE,AQR,HSPA2,HSPA1A,HSPA1B,HSPA6
ko04620	Toll-like receptor signaling pathway	0.926889441533013	-0.0759209853260749	106	41	0.0135224274406332	3032	6715	7189,942,1326,8737,3661,1432,5606,3725,3654,23533,3551,4790,5296,6351,5601,5290,8503,5600,54106,6885,7100,29110,5609,207,5295,929,3454,54472,1513,2353,5605,8772,8517,9641,23118,10000,3576,4792,3665,7187,6300	TRAF6,CD86,MAP3K8,RIPK1,IRF3,MAPK14,MAP2K3,JUN,IRAK1,PIK3R5,IKBKB,NFKB1,PIK3R2,CCL4,MAPK9,PIK3CA,PIK3R3,MAPK11,TLR9,MAP3K7,TLR5,TBK1,MAP2K7,AKT1,PIK3R1,CD14,IFNAR1,TOLLIP,CTSK,FOS,MAP2K2,FADD,IKBKG,IKBKE,TAB2,AKT3,IL8,NFKBIA,IRF7,TRAF3,MAPK12
hsa04620	Toll-like receptor signaling pathway	0.926889441533013	-0.0759209853260749	106	41	0.0135224274406332	3032	6715	7189,942,1326,8737,3661,1432,5606,3725,3654,23533,3551,4790,5296,6351,5601,5290,8503,5600,54106,6885,7100,29110,5609,207,5295,929,3454,54472,1513,2353,5605,8772,8517,9641,23118,10000,3576,4792,3665,7187,6300	TRAF6,CD86,MAP3K8,RIPK1,IRF3,MAPK14,MAP2K3,JUN,IRAK1,PIK3R5,IKBKB,NFKB1,PIK3R2,CCL4,MAPK9,PIK3CA,PIK3R3,MAPK11,TLR9,MAP3K7,TLR5,TBK1,MAP2K7,AKT1,PIK3R1,CD14,IFNAR1,TOLLIP,CTSK,FOS,MAP2K2,FADD,IKBKG,IKBKE,TAB2,AKT3,IL8,NFKBIA,IRF7,TRAF3,MAPK12
hsa04612	Antigen processing and presentation	0.928213518355124	-0.0744934882268998	82	31	0.0102242744063325	3032	6715	920,1508,5721,3326,3309,3312,6890,567,821,3303,972,4261,3105,3304,3310,3123,811,3113,925,1520,4800,3308,10437,3320,3107,5993,5641,1385,10197,3306,3802	CD4,CTSB,PSME2,HSP90AB1,HSPA5,HSPA8,TAP1,B2M,CANX,HSPA1A,CD74,CIITA,HLA-A,HSPA1B,HSPA6,HLA-DRB1,CALR,HLA-DPA1,CD8A,CTSS,NFYA,HSPA4,IFI30,HSP90AA1,HLA-C,RFX5,LGMN,CREB1,PSME3,HSPA2,KIR2DL1
ko04612	Antigen processing and presentation	0.928213518355124	-0.0744934882268998	82	31	0.0102242744063325	3032	6715	920,1508,5721,3326,3309,3312,6890,567,821,3303,972,4261,3105,3304,3310,3123,811,3113,925,1520,4800,3308,10437,3320,3107,5993,5641,1385,10197,3306,3802	CD4,CTSB,PSME2,HSP90AB1,HSPA5,HSPA8,TAP1,B2M,CANX,HSPA1A,CD74,CIITA,HLA-A,HSPA1B,HSPA6,HLA-DRB1,CALR,HLA-DPA1,CD8A,CTSS,NFYA,HSPA4,IFI30,HSP90AA1,HLA-C,RFX5,LGMN,CREB1,PSME3,HSPA2,KIR2DL1
hsa_M00354	Spliceosome, U4/U6.U5 tri-snRNP	0.933225467152695	-0.06910844907361	30	10	0.00329815303430079	3032	6715	6632,11157,26121,6628,25804,9128,9129,6635,10907,10421	SNRPD1,LSM6,PRPF31,SNRPB,LSM4,PRPF4,PRPF3,SNRPE,TXNL4A,CD2BP2
M00354	Spliceosome, U4/U6.U5 tri-snRNP	0.933225467152695	-0.06910844907361	30	10	0.00329815303430079	3032	6715	6632,11157,26121,6628,25804,9128,9129,6635,10907,10421	SNRPD1,LSM6,PRPF31,SNRPB,LSM4,PRPF4,PRPF3,SNRPE,TXNL4A,CD2BP2
hsa_M00010	Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate	0.937987425567544	-0.0640187356440793	8	2	0.000659630606860158	3032	6715	3418,48	IDH2,ACO1
M00010	Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate	0.937987425567544	-0.0640187356440793	8	2	0.000659630606860158	3032	6715	3418,48	IDH2,ACO1
ko00790	Folate biosynthesis	0.938377029453059	-0.063603460359929	14	4	0.00131926121372032	3032	6715	5805,2356,248,250	PTS,FPGS,ALPI,ALPP
hsa00790	Folate biosynthesis	0.938377029453059	-0.063603460359929	14	4	0.00131926121372032	3032	6715	5805,2356,248,250	PTS,FPGS,ALPI,ALPP
ko00500	Starch and sucrose metabolism	0.941768565595206	-0.0599957186725743	56	20	0.00659630606860158	3032	6715	2632,5236,2548,7363,7360,7358,6476,80201,92579,5834,80146,5167,2645,3099,2997,54578,11181,3098,2821,3101	GBE1,PGM1,GAA,UGT2B4,UGP2,UGDH,SI,HKDC1,G6PC3,PYGB,UXS1,ENPP1,GCK,HK2,GYS1,UGT1A6,TREH,HK1,GPI,HK3
hsa00500	Starch and sucrose metabolism	0.941768565595206	-0.0599957186725743	56	20	0.00659630606860158	3032	6715	2632,5236,2548,7363,7360,7358,6476,80201,92579,5834,80146,5167,2645,3099,54578,2997,11181,3098,2821,3101	GBE1,PGM1,GAA,UGT2B4,UGP2,UGDH,SI,HKDC1,G6PC3,PYGB,UXS1,ENPP1,GCK,HK2,UGT1A6,GYS1,TREH,HK1,GPI,HK3
ko04672	Intestinal immune network for IgA production	0.942001368429548	-0.0597485517215338	51	18	0.00593667546174142	3032	6715	56477,3601,115650,3600,942,3565,3586,5284,29851,23495,3113,4055,3123,23308,9020,940,3567,6370	CCL28,IL15RA,TNFRSF13C,IL15,CD86,IL4,IL10,PIGR,ICOS,TNFRSF13B,HLA-DPA1,LTBR,HLA-DRB1,ICOSLG,MAP3K14,CD28,IL5,CCL25
hsa04672	Intestinal immune network for IgA production	0.942001368429548	-0.0597485517215338	51	18	0.00593667546174142	3032	6715	56477,3601,115650,3600,942,3565,3586,5284,29851,23495,3113,4055,3123,23308,9020,940,3567,6370	CCL28,IL15RA,TNFRSF13C,IL15,CD86,IL4,IL10,PIGR,ICOS,TNFRSF13B,HLA-DPA1,LTBR,HLA-DRB1,ICOSLG,MAP3K14,CD28,IL5,CCL25
hsa05150	Staphylococcus aureus infection	0.947814822174554	-0.0535961310664406	59	21	0.00692612137203166	3032	6715	718,5724,2213,3075,6403,6404,3586,2214,3383,3123,4153,3113,3689,713,712,2209,1675,714,2212,9103,10747	C3,PTAFR,FCGR2B,CFH,SELP,SELPLG,IL10,FCGR3A,ICAM1,HLA-DRB1,MBL2,HLA-DPA1,ITGB2,C1QB,C1QA,FCGR1A,CFD,C1QC,FCGR2A,FCGR2C,MASP2
ko05150	Staphylococcus aureus infection	0.947814822174554	-0.0535961310664406	59	21	0.00692612137203166	3032	6715	718,5724,2213,3075,6403,6404,3586,2214,3383,3123,4153,3113,3689,713,712,2209,1675,714,2212,9103,10747	C3,PTAFR,FCGR2B,CFH,SELP,SELPLG,IL10,FCGR3A,ICAM1,HLA-DRB1,MBL2,HLA-DPA1,ITGB2,C1QB,C1QA,FCGR1A,CFD,C1QC,FCGR2A,FCGR2C,MASP2
hsa05010	Alzheimer's disease	0.948594991872046	-0.0527733450465348	168	66	0.0217678100263852	3032	6715	4712,29796,1346,9451,51079,637,351,5331,1020,517,5664,7385,4715,4731,779,4700,4720,2597,1350,51107,27089,514,3710,125965,126328,7132,9377,2932,5533,22926,4713,1340,4729,6391,489,4726,322,54205,4697,1327,1345,374291,824,4695,51806,10476,4728,1537,5330,516,6868,2902,8772,8851,355,6390,440567,3708,9167,1351,163688,5332,317,498,810,4311	NDUFB6,UQCR10,COX7A1,EIF2AK3,NDUFA13,BID,APP,PLCB3,CDK5,ATP5G2,PSEN2,UQCRC2,NDUFB9,NDUFV3,CACNA1S,NDUFA6,NDUFS2,GAPDH,COX7C,APH1A,UQCRQ,ATP5E,ITPR3,COX6B2,NDUFA11,TNFRSF1A,COX5A,GSK3B,PPP3CC,ATF6,NDUFB7,COX6B1,NDUFV2,SDHC,ATP2A3,NDUFS6,APBB1,CYCS,NDUFA4,COX4I1,COX6C,NDUFS7,CAPN2,NDUFA2,CALML5,ATP5H,NDUFS8,CYC1,PLCB2,ATP5G1,ADAM17,GRIN1,FADD,CDK5R1,FAS,SDHB,UQCRHL,ITPR1,COX7A2L,COX8A,CALML6,PLCB4,APAF1,ATP5A1,CALML3,MME
ko05010	Alzheimer's disease	0.948594991872046	-0.0527733450465348	168	66	0.0217678100263852	3032	6715	4712,29796,1346,9451,51079,637,351,5331,1020,517,5664,7385,4715,4731,779,4700,4720,2597,1350,51107,27089,514,3710,125965,126328,7132,9377,2932,5533,22926,4713,1340,4729,6391,489,4726,322,54205,4697,1327,1345,374291,824,4695,51806,10476,4728,1537,5330,516,6868,2902,8772,8851,355,6390,440567,3708,9167,1351,163688,5332,317,498,810,4311	NDUFB6,UQCR10,COX7A1,EIF2AK3,NDUFA13,BID,APP,PLCB3,CDK5,ATP5G2,PSEN2,UQCRC2,NDUFB9,NDUFV3,CACNA1S,NDUFA6,NDUFS2,GAPDH,COX7C,APH1A,UQCRQ,ATP5E,ITPR3,COX6B2,NDUFA11,TNFRSF1A,COX5A,GSK3B,PPP3CC,ATF6,NDUFB7,COX6B1,NDUFV2,SDHC,ATP2A3,NDUFS6,APBB1,CYCS,NDUFA4,COX4I1,COX6C,NDUFS7,CAPN2,NDUFA2,CALML5,ATP5H,NDUFS8,CYC1,PLCB2,ATP5G1,ADAM17,GRIN1,FADD,CDK5R1,FAS,SDHB,UQCRHL,ITPR1,COX7A2L,COX8A,CALML6,PLCB4,APAF1,ATP5A1,CALML3,MME
ko05034	Alcoholism	0.949607712976323	-0.0517063133772859	180	71	0.0234168865435356	3032	6715	64764,126961,84254,5894,79885,8349,2782,8358,10013,8290,5566,2783,25759,440689,6464,53358,2354,5499,1386,3017,468,8370,6531,2788,85236,90993,3021,9759,59345,4128,8337,3020,8338,128312,3066,286436,399694,1388,8970,9586,136,83933,317772,9734,51806,51564,2793,653604,9555,51764,1385,2771,116444,92815,1644,8336,148327,10645,8841,2902,2786,3845,158983,111,163688,6571,4915,3265,810,333932,1812	CREB3L2,HIST2H3C,CAMKK1,RAF1,HDAC11,HIST2H2BE,GNB1,HIST1H3B,HDAC6,HIST3H3,PRKACA,GNB2,SHC2,HIST2H2BF,SHC1,SHC3,FOSB,PPP1CA,ATF2,HIST1H2BD,ATF4,HIST2H4A,SLC6A3,GNG7,HIST1H2BK,CREB3L1,H3F3B,HDAC4,GNB4,MAOA,HIST2H2AA3,H3F3A,HIST2H2AC,HIST3H2BB,HDAC2,H2BFM,SHC4,ATF6B,HIST1H2BJ,CREB5,ADORA2B,HDAC10,HIST2H2AB,HDAC9,CALML5,HDAC7,GNGT2,HIST2H3D,H2AFY,GNG13,CREB1,GNAI2,GRIN3B,HIST3H2A,DDC,HIST1H2AM,CREB3L4,CAMKK2,HDAC3,GRIN1,GNG4,KRAS,H2BFWT,ADCY5,CALML6,SLC18A2,NTRK2,HRAS,CALML3,HIST2H3A,DRD1
hsa05034	Alcoholism	0.949607712976323	-0.0517063133772859	180	71	0.0234168865435356	3032	6715	64764,126961,84254,5894,79885,8349,2782,8358,10013,8290,5566,2783,25759,440689,6464,53358,2354,5499,1386,3017,468,8370,6531,2788,85236,90993,3021,9759,59345,4128,8337,3020,8338,128312,3066,286436,399694,1388,8970,9586,136,83933,317772,9734,51806,51564,2793,653604,9555,51764,1385,2771,116444,92815,1644,8336,148327,10645,8841,2902,2786,3845,158983,111,163688,6571,4915,3265,810,333932,1812	CREB3L2,HIST2H3C,CAMKK1,RAF1,HDAC11,HIST2H2BE,GNB1,HIST1H3B,HDAC6,HIST3H3,PRKACA,GNB2,SHC2,HIST2H2BF,SHC1,SHC3,FOSB,PPP1CA,ATF2,HIST1H2BD,ATF4,HIST2H4A,SLC6A3,GNG7,HIST1H2BK,CREB3L1,H3F3B,HDAC4,GNB4,MAOA,HIST2H2AA3,H3F3A,HIST2H2AC,HIST3H2BB,HDAC2,H2BFM,SHC4,ATF6B,HIST1H2BJ,CREB5,ADORA2B,HDAC10,HIST2H2AB,HDAC9,CALML5,HDAC7,GNGT2,HIST2H3D,H2AFY,GNG13,CREB1,GNAI2,GRIN3B,HIST3H2A,DDC,HIST1H2AM,CREB3L4,CAMKK2,HDAC3,GRIN1,GNG4,KRAS,H2BFWT,ADCY5,CALML6,SLC18A2,NTRK2,HRAS,CALML3,HIST2H3A,DRD1
ko00232	Caffeine metabolism	0.950426938647707	-0.0508439862387271	5	1	0.000329815303430079	3032	6715	1548	CYP2A6
hsa00400	Phenylalanine, tyrosine and tryptophan biosynthesis	0.950426938647707	-0.0508439862387271	5	1	0.000329815303430079	3032	6715	2805	GOT1
hsa_M00044	Tyrosine degradation, tyrosine => homogentisate	0.950426938647707	-0.0508439862387271	5	1	0.000329815303430079	3032	6715	2954	GSTZ1
ko00400	Phenylalanine, tyrosine and tryptophan biosynthesis	0.950426938647707	-0.0508439862387271	5	1	0.000329815303430079	3032	6715	2805	GOT1
M00044	Tyrosine degradation, tyrosine => homogentisate	0.950426938647707	-0.0508439862387271	5	1	0.000329815303430079	3032	6715	2954	GSTZ1
hsa00232	Caffeine metabolism	0.950426938647707	-0.0508439862387271	5	1	0.000329815303430079	3032	6715	1548	CYP2A6
hsa00062	Fatty acid elongation	0.950825482154095	-0.0504247431041859	23	7	0.00230870712401055	3032	6715	60481,3033,6785,64834,79071,51144,11332	ELOVL5,HADH,ELOVL4,ELOVL1,ELOVL6,HSD17B12,ACOT7
ko00062	Fatty acid elongation	0.950825482154095	-0.0504247431041859	23	7	0.00230870712401055	3032	6715	60481,3033,6785,64834,79071,11332,51144	ELOVL5,HADH,ELOVL4,ELOVL1,ELOVL6,ACOT7,HSD17B12
hsa03010	Ribosome	0.951402008121103	-0.0498185842850031	135	52	0.0171503957783641	3032	6715	6202,6181,51116,6235,23521,64963,6135,6137,51187,6234,6141,6205,6170,64981,65003,219927,29088,6159,6154,7311,6160,79590,6169,6132,6229,55173,6142,6232,55168,4736,63931,64928,6203,3921,6189,25873,55052,6191,54460,10573,6161,9553,6208,6223,6176,6206,65008,6146,6188,51021,28998,6150	RPS8,RPLP2,MRPS2,RPS29,RPL13A,MRPS11,RPL11,RPL13,RSL24D1,RPS28,RPL18,RPS11,RPL39,MRPL34,MRPL11,MRPL21,MRPL15,RPL29,RPL26,UBA52,RPL31,MRPL24,RPL38,RPL8,RPS24,MRPS10,RPL18A,RPS27,MRPS18A,RPL10A,MRPS14,MRPL14,RPS9,RPSA,RPS3A,RPL36,MRPL20,RPS4X,MRPS21,MRPL28,RPL32,MRPL33,RPS14,RPS19,RPLP1,RPS12,MRPL1,RPL22,RPS3,MRPS16,MRPL13,MRPL23
ko03010	Ribosome	0.951402008121103	-0.0498185842850031	135	52	0.0171503957783641	3032	6715	6202,6181,51116,6235,23521,64963,6135,6137,51187,6234,6141,6170,6205,64981,65003,219927,29088,6154,6159,7311,6160,6132,79590,6169,55173,6229,6232,6142,55168,4736,63931,64928,6203,3921,6189,55052,25873,6191,54460,10573,6161,6208,9553,6176,6223,6206,65008,6146,6188,51021,28998,6150	RPS8,RPLP2,MRPS2,RPS29,RPL13A,MRPS11,RPL11,RPL13,RSL24D1,RPS28,RPL18,RPL39,RPS11,MRPL34,MRPL11,MRPL21,MRPL15,RPL26,RPL29,UBA52,RPL31,RPL8,MRPL24,RPL38,MRPS10,RPS24,RPS27,RPL18A,MRPS18A,RPL10A,MRPS14,MRPL14,RPS9,RPSA,RPS3A,MRPL20,RPL36,RPS4X,MRPS21,MRPL28,RPL32,RPS14,MRPL33,RPLP1,RPS19,RPS12,MRPL1,RPL22,RPS3,MRPS16,MRPL13,MRPL23
ko04140	Regulation of autophagy	0.954922611825547	-0.046124976522546	34	11	0.00362796833773087	3032	6715	5563,25989,5562,11345,9140,8408,9474,23192,9706,3630,23710	PRKAA2,ULK3,PRKAA1,GABARAPL2,ATG12,ULK1,ATG5,ATG4B,ULK2,INS,GABARAPL1
ko05143	African trypanosomiasis	0.954922611825547	-0.046124976522546	34	11	0.00362796833773087	3032	6715	356,5332,3606,54106,3586,5578,5330,3383,7064,355,5331	FASLG,PLCB4,IL18,TLR9,IL10,PRKCA,PLCB2,ICAM1,THOP1,FAS,PLCB3
hsa05143	African trypanosomiasis	0.954922611825547	-0.046124976522546	34	11	0.00362796833773087	3032	6715	356,5332,3606,54106,3586,5578,5330,3383,7064,355,5331	FASLG,PLCB4,IL18,TLR9,IL10,PRKCA,PLCB2,ICAM1,THOP1,FAS,PLCB3
hsa04140	Regulation of autophagy	0.954922611825547	-0.046124976522546	34	11	0.00362796833773087	3032	6715	5563,25989,5562,11345,9140,8408,9474,23192,9706,3630,23710	PRKAA2,ULK3,PRKAA1,GABARAPL2,ATG12,ULK1,ATG5,ATG4B,ULK2,INS,GABARAPL1
ko00040	Pentose and glucuronate interconversions	0.954922611825547	-0.046124976522546	34	11	0.00362796833773087	3032	6715	27294,7363,7360,51181,7358,57016,54578,219,6120,224,51084	DHDH,UGT2B4,UGP2,DCXR,UGDH,AKR1B10,UGT1A6,ALDH1B1,RPE,ALDH3A2,CRYL1
hsa00040	Pentose and glucuronate interconversions	0.954922611825547	-0.046124976522546	34	11	0.00362796833773087	3032	6715	27294,7363,7360,51181,7358,57016,54578,219,6120,224,51084	DHDH,UGT2B4,UGP2,DCXR,UGDH,AKR1B10,UGT1A6,ALDH1B1,RPE,ALDH3A2,CRYL1
hsa05012	Parkinson's disease	0.957145229768686	-0.0438001437986587	131	50	0.016490765171504	3032	6715	5071,4729,7317,4712,6391,29796,1346,4726,1327,4697,54205,1345,51079,11315,374291,4695,517,10476,7385,7419,4728,7326,4715,4731,1537,4700,4720,7327,10105,516,1350,27089,6531,514,118424,7416,6390,125965,291,440567,126328,9167,1351,9377,317,498,6571,4713,9627,1340	PARK2,NDUFV2,UBA1,NDUFB6,SDHC,UQCR10,COX7A1,NDUFS6,COX4I1,NDUFA4,CYCS,COX6C,NDUFA13,PARK7,NDUFS7,NDUFA2,ATP5G2,ATP5H,UQCRC2,VDAC3,NDUFS8,UBE2G1,NDUFB9,NDUFV3,CYC1,NDUFA6,NDUFS2,UBE2G2,PPIF,ATP5G1,COX7C,UQCRQ,SLC6A3,ATP5E,UBE2J2,VDAC1,SDHB,COX6B2,SLC25A4,UQCRHL,NDUFA11,COX7A2L,COX8A,COX5A,APAF1,ATP5A1,SLC18A2,NDUFB7,SNCAIP,COX6B1
hsa_M00290	Holo-TFIIH complex	0.958922545606245	-0.0419449731516246	12	3	0.000989445910290238	3032	6715	2967,902,2968	GTF2H3,CCNH,GTF2H4
M00036	Leucine degradation, leucine => acetoacetate + acetyl-CoA	0.958922545606245	-0.0419449731516246	12	3	0.000989445910290238	3032	6715	594,64087,56922	BCKDHB,MCCC2,MCCC1
hsa_M00036	Leucine degradation, leucine => acetoacetate + acetyl-CoA	0.958922545606245	-0.0419449731516246	12	3	0.000989445910290238	3032	6715	594,64087,56922	BCKDHB,MCCC2,MCCC1
M00290	Holo-TFIIH complex	0.958922545606245	-0.0419449731516246	12	3	0.000989445910290238	3032	6715	2967,902,2968	GTF2H3,CCNH,GTF2H4
hsa_M00177	Ribosome, eukaryotes	0.959548325603506	-0.0412925994003772	90	33	0.0108839050131926	3032	6715	6202,6181,6235,23521,6135,6137,51187,6234,6141,6205,6170,6154,6159,7311,6160,6169,6132,6229,6232,6142,4736,6203,3921,25873,6189,6191,6161,6208,6176,6223,6206,6188,6146	RPS8,RPLP2,RPS29,RPL13A,RPL11,RPL13,RSL24D1,RPS28,RPL18,RPS11,RPL39,RPL26,RPL29,UBA52,RPL31,RPL38,RPL8,RPS24,RPS27,RPL18A,RPL10A,RPS9,RPSA,RPL36,RPS3A,RPS4X,RPL32,RPS14,RPLP1,RPS19,RPS12,RPS3,RPL22
M00177	Ribosome, eukaryotes	0.959548325603506	-0.0412925994003772	90	33	0.0108839050131926	3032	6715	6202,6181,6235,23521,6135,6137,51187,6234,6141,6205,6170,6154,6159,7311,6160,6169,6132,6229,6232,6142,4736,6203,3921,25873,6189,6191,6161,6208,6176,6223,6206,6188,6146	RPS8,RPLP2,RPS29,RPL13A,RPL11,RPL13,RSL24D1,RPS28,RPL18,RPS11,RPL39,RPL26,RPL29,UBA52,RPL31,RPL38,RPL8,RPS24,RPS27,RPL18A,RPL10A,RPS9,RPSA,RPL36,RPS3A,RPS4X,RPL32,RPS14,RPLP1,RPS19,RPS12,RPS3,RPL22
hsa03022	Basal transcription factors	0.961309142624723	-0.0394592332672305	45	15	0.00494722955145119	3032	6715	8148,6873,6881,2967,2961,902,2957,2968,6908,6874,9569,27097,10629,387332,2969	TAF15,TAF2,TAF10,GTF2H3,GTF2E2,CCNH,GTF2A1,GTF2H4,TBP,TAF4,GTF2IRD1,TAF5L,TAF6L,TBPL2,GTF2I
ko03022	Basal transcription factors	0.961309142624723	-0.0394592332672305	45	15	0.00494722955145119	3032	6715	8148,6873,6881,2967,2961,902,2957,6908,2968,6874,9569,27097,10629,387332,2969	TAF15,TAF2,TAF10,GTF2H3,GTF2E2,CCNH,GTF2A1,TBP,GTF2H4,TAF4,GTF2IRD1,TAF5L,TAF6L,TBPL2,GTF2I
hsa04977	Vitamin digestion and absorption	0.964993946241361	-0.0356334509878434	24	7	0.00230870712401055	3032	6715	5948,6573,949,151056,9963,9227,10560	RBP2,SLC19A1,SCARB1,PLB1,SLC23A1,LRAT,SLC19A2
ko04977	Vitamin digestion and absorption	0.964993946241361	-0.0356334509878434	24	7	0.00230870712401055	3032	6715	5948,6573,949,151056,9963,9227,10560	RBP2,SLC19A1,SCARB1,PLB1,SLC23A1,LRAT,SLC19A2
hsa01212	Fatty acid metabolism	0.965232428277309	-0.0353863483264046	48	16	0.00527704485488127	3032	6715	51703,35,60481,9415,2180,3033,79071,2181,23305,55301,2194,27349,30,37,8310,51144	ACSL5,ACADS,ELOVL5,FADS2,ACSL1,HADH,ELOVL6,ACSL3,ACSL6,OLAH,FASN,MCAT,ACAA1,ACADVL,ACOX3,HSD17B12
ko01212	Fatty acid metabolism	0.965232428277309	-0.0353863483264046	48	16	0.00527704485488127	3032	6715	51703,35,60481,9415,2180,3033,79071,2181,23305,55301,2194,27349,30,37,8310,51144	ACSL5,ACADS,ELOVL5,FADS2,ACSL1,HADH,ELOVL6,ACSL3,ACSL6,OLAH,FASN,MCAT,ACAA1,ACADVL,ACOX3,HSD17B12
M00073	N-glycan precursor trimming	0.97282716548694	-0.0275488431118786	6	1	0.000329815303430079	3032	6715	11253	MAN1B1
hsa_M00085	Fatty acid biosynthesis, elongation, mitochondria	0.97282716548694	-0.0275488431118786	6	1	0.000329815303430079	3032	6715	3033	HADH
hsa_M00073	N-glycan precursor trimming	0.97282716548694	-0.0275488431118786	6	1	0.000329815303430079	3032	6715	11253	MAN1B1
M00284	Origin recognition complex	0.97282716548694	-0.0275488431118786	6	1	0.000329815303430079	3032	6715	4999	ORC2
hsa_M00284	Origin recognition complex	0.97282716548694	-0.0275488431118786	6	1	0.000329815303430079	3032	6715	4999	ORC2
M00085	Fatty acid biosynthesis, elongation, mitochondria	0.97282716548694	-0.0275488431118786	6	1	0.000329815303430079	3032	6715	3033	HADH
ko00140	Steroid hormone biosynthesis	0.974684432353562	-0.025641519497761	57	19	0.0062664907651715	3032	6715	3292,1588,7363,1589,3294,8630,6716,51478,1585,1646,1584,1583,3291,3290,79644,54578,1312,6820,51144	HSD17B1,CYP19A1,UGT2B4,CYP21A2,HSD17B2,HSD17B6,SRD5A2,HSD17B7,CYP11B2,AKR1C2,CYP11B1,CYP11A1,HSD11B2,HSD11B1,SRD5A3,UGT1A6,COMT,SULT2B1,HSD17B12
hsa00140	Steroid hormone biosynthesis	0.974684432353562	-0.025641519497761	57	19	0.0062664907651715	3032	6715	3292,1588,7363,1589,3294,6716,8630,51478,1585,1584,1646,1583,3291,3290,79644,54578,1312,6820,51144	HSD17B1,CYP19A1,UGT2B4,CYP21A2,HSD17B2,SRD5A2,HSD17B6,HSD17B7,CYP11B2,CYP11B1,AKR1C2,CYP11A1,HSD11B2,HSD11B1,SRD5A3,UGT1A6,COMT,SULT2B1,HSD17B12
ko00071	Fatty acid degradation	0.974988147426311	-0.0253299645440155	44	14	0.00461741424802111	3032	6715	35,51703,2180,3033,2181,23305,10455,501,219,2639,37,30,8310,224	ACADS,ACSL5,ACSL1,HADH,ACSL3,ACSL6,ECI2,ALDH7A1,ALDH1B1,GCDH,ACADVL,ACAA1,ACOX3,ALDH3A2
hsa00071	Fatty acid degradation	0.974988147426311	-0.0253299645440155	44	14	0.00461741424802111	3032	6715	51703,35,2180,3033,2181,23305,10455,501,219,2639,30,37,8310,224	ACSL5,ACADS,ACSL1,HADH,ACSL3,ACSL6,ECI2,ALDH7A1,ALDH1B1,GCDH,ACAA1,ACADVL,ACOX3,ALDH3A2
hsa04122	Sulfur relay system	0.977331593680511	-0.0229292846447655	10	2	0.000659630606860158	3032	6715	27304,90353	MOCS3,CTU1
ko00130	Ubiquinone and other terpenoid-quinone biosynthesis	0.977331593680511	-0.0229292846447655	10	2	0.000659630606860158	3032	6715	10229,1728	COQ7,NQO1
hsa00130	Ubiquinone and other terpenoid-quinone biosynthesis	0.977331593680511	-0.0229292846447655	10	2	0.000659630606860158	3032	6715	1728,10229	NQO1,COQ7
ko04122	Sulfur relay system	0.977331593680511	-0.0229292846447655	10	2	0.000659630606860158	3032	6715	27304,90353	MOCS3,CTU1
hsa05310	Asthma	0.980130731937432	-0.0200693162783444	34	10	0.00329815303430079	3032	6715	3123,3562,3113,2207,3596,3565,3578,3586,2205,3567	HLA-DRB1,IL3,HLA-DPA1,FCER1G,IL13,IL4,IL9,IL10,FCER1A,IL5
ko05310	Asthma	0.980130731937432	-0.0200693162783444	34	10	0.00329815303430079	3032	6715	3123,3562,3113,2207,3596,3565,3578,3586,2205,3567	HLA-DRB1,IL3,HLA-DPA1,FCER1G,IL13,IL4,IL9,IL10,FCER1A,IL5
ko03320	PPAR signaling pathway	0.983306590051859	-0.0168343152436461	69	23	0.00758575197889182	3032	6715	5170,51703,2170,6258,9415,10580,2180,2181,6256,336,30,948,51129,7316,364,28965,1622,23305,2172,5105,10999,8310,2168	PDPK1,ACSL5,FABP3,RXRG,FADS2,SORBS1,ACSL1,ACSL3,RXRA,APOA2,ACAA1,CD36,ANGPTL4,UBC,AQP7,SLC27A6,DBI,ACSL6,FABP6,PCK1,SLC27A4,ACOX3,FABP1
hsa03320	PPAR signaling pathway	0.983306590051859	-0.0168343152436461	69	23	0.00758575197889182	3032	6715	51703,2170,5170,6258,9415,10580,2180,2181,6256,336,30,948,51129,7316,364,28965,2172,1622,23305,5105,10999,8310,2168	ACSL5,FABP3,PDPK1,RXRG,FADS2,SORBS1,ACSL1,ACSL3,RXRA,APOA2,ACAA1,CD36,ANGPTL4,UBC,AQP7,SLC27A6,FABP6,DBI,ACSL6,PCK1,SLC27A4,ACOX3,FABP1
hsa_M00147	NADH dehydrogenase (ubiquinone) 1 beta subcomplex	0.983545097369829	-0.0165917882441124	14	3	0.000989445910290238	3032	6715	4715,4712,4713	NDUFB9,NDUFB6,NDUFB7
M00147	NADH dehydrogenase (ubiquinone) 1 beta subcomplex	0.983545097369829	-0.0165917882441124	14	3	0.000989445910290238	3032	6715	4715,4712,4713	NDUFB9,NDUFB6,NDUFB7
ko05168	Herpes simplex infection	0.98423015201332	-0.0158955149564165	188	71	0.0234168865435356	3032	6715	7874,7189,3600,9451,6890,3661,10629,8864,3113,6427,6672,3551,4790,5818,27097,54106,57506,5499,2969,3054,718,6881,29997,983,7297,6426,9021,8517,7185,1616,23118,5187,406,7132,6500,3665,7187,6041,7188,6908,7186,6431,9569,54205,3105,3725,3123,10189,5601,5781,10379,3717,3107,6885,1936,3150,29110,10445,3460,27102,3454,2353,972,8772,355,9641,6874,4792,356,387332,8863	USP7,TRAF6,IL15,EIF2AK3,TAP1,IRF3,TAF6L,PER2,HLA-DPA1,SRSF2,SP100,IKBKB,NFKB1,PVRL1,TAF5L,TLR9,MAVS,PPP1CA,GTF2I,HCFC1,C3,TAF10,GLTSCR2,CDK1,TYK2,SRSF1,SOCS3,IKBKG,TRAF1,DAXX,TAB2,PER1,ARNTL,TNFRSF1A,SKP1,IRF7,TRAF3,RNASEL,TRAF5,TBP,TRAF2,SRSF6,GTF2IRD1,CYCS,HLA-A,JUN,HLA-DRB1,ALYREF,MAPK9,PTPN11,IRF9,JAK2,HLA-C,MAP3K7,EEF1D,HMGN1,TBK1,MCRS1,IFNGR2,EIF2AK1,IFNAR1,FOS,CD74,FADD,FAS,IKBKE,TAF4,NFKBIA,FASLG,TBPL2,PER3
hsa05168	Herpes simplex infection	0.98423015201332	-0.0158955149564165	188	71	0.0234168865435356	3032	6715	7874,7189,3600,9451,6890,3661,10629,8864,3113,6427,6672,3551,4790,5818,27097,54106,57506,5499,2969,3054,718,6881,29997,983,7297,6426,9021,8517,7185,1616,23118,5187,406,7132,6500,3665,7187,6041,7188,6908,7186,6431,9569,54205,3105,3725,3123,10189,5601,5781,10379,3717,3107,6885,1936,3150,29110,10445,3460,27102,3454,2353,972,8772,355,9641,6874,4792,356,387332,8863	USP7,TRAF6,IL15,EIF2AK3,TAP1,IRF3,TAF6L,PER2,HLA-DPA1,SRSF2,SP100,IKBKB,NFKB1,PVRL1,TAF5L,TLR9,MAVS,PPP1CA,GTF2I,HCFC1,C3,TAF10,GLTSCR2,CDK1,TYK2,SRSF1,SOCS3,IKBKG,TRAF1,DAXX,TAB2,PER1,ARNTL,TNFRSF1A,SKP1,IRF7,TRAF3,RNASEL,TRAF5,TBP,TRAF2,SRSF6,GTF2IRD1,CYCS,HLA-A,JUN,HLA-DRB1,ALYREF,MAPK9,PTPN11,IRF9,JAK2,HLA-C,MAP3K7,EEF1D,HMGN1,TBK1,MCRS1,IFNGR2,EIF2AK1,IFNAR1,FOS,CD74,FADD,FAS,IKBKE,TAF4,NFKBIA,FASLG,TBPL2,PER3
hsa_M00391	Exosome, eukaryotes	0.986471359530189	-0.0136209863482247	11	2	0.000659630606860158	3032	6715	54512,56915	EXOSC4,EXOSC5
M00391	Exosome, eukaryotes	0.986471359530189	-0.0136209863482247	11	2	0.000659630606860158	3032	6715	54512,56915	EXOSC4,EXOSC5
hsa05323	Rheumatoid arthritis	0.986871034244518	-0.0132159124785767	93	32	0.0105540897097625	3032	6715	3600,942,537,90423,3606,7042,525,3383,3123,3725,3113,533,51606,8792,9114,9550,6364,7422,1437,2353,1513,3689,10312,1435,3576,2321,127124,527,528,8992,940,284	IL15,CD86,ATP6AP1,ATP6V1E2,IL18,TGFB2,ATP6V1B1,ICAM1,HLA-DRB1,JUN,HLA-DPA1,ATP6V0B,ATP6V1H,TNFRSF11A,ATP6V0D1,ATP6V1G1,CCL20,VEGFA,CSF2,FOS,CTSK,ITGB2,TCIRG1,CSF1,IL8,FLT1,ATP6V1G3,ATP6V0C,ATP6V1C1,ATP6V0E1,CD28,ANGPT1
ko05323	Rheumatoid arthritis	0.986871034244518	-0.0132159124785767	93	32	0.0105540897097625	3032	6715	3600,942,537,90423,3606,7042,525,3383,3123,3725,3113,533,51606,8792,9114,9550,6364,7422,1437,2353,1513,3689,10312,1435,3576,2321,127124,527,528,8992,940,284	IL15,CD86,ATP6AP1,ATP6V1E2,IL18,TGFB2,ATP6V1B1,ICAM1,HLA-DRB1,JUN,HLA-DPA1,ATP6V0B,ATP6V1H,TNFRSF11A,ATP6V0D1,ATP6V1G1,CCL20,VEGFA,CSF2,FOS,CTSK,ITGB2,TCIRG1,CSF1,IL8,FLT1,ATP6V1G3,ATP6V0C,ATP6V1C1,ATP6V0E1,CD28,ANGPT1
hsa05330	Allograft rejection	0.987676569014403	-0.0123999941251835	41	12	0.00395778364116095	3032	6715	3123,3113,942,3565,356,3586,3107,5551,940,3567,3105,355	HLA-DRB1,HLA-DPA1,CD86,IL4,FASLG,IL10,HLA-C,PRF1,CD28,IL5,HLA-A,FAS
ko05330	Allograft rejection	0.987676569014403	-0.0123999941251835	41	12	0.00395778364116095	3032	6715	3123,3113,942,3565,356,3586,3107,5551,940,3567,3105,355	HLA-DRB1,HLA-DPA1,CD86,IL4,FASLG,IL10,HLA-C,PRF1,CD28,IL5,HLA-A,FAS
hsa00053	Ascorbate and aldarate metabolism	0.988118426586485	-0.0119527234514221	27	7	0.00230870712401055	3032	6715	54578,501,7363,219,55586,224,7358	UGT1A6,ALDH7A1,UGT2B4,ALDH1B1,MIOX,ALDH3A2,UGDH
ko00053	Ascorbate and aldarate metabolism	0.988118426586485	-0.0119527234514221	27	7	0.00230870712401055	3032	6715	54578,501,7363,219,55586,224,7358	UGT1A6,ALDH7A1,UGT2B4,ALDH1B1,MIOX,ALDH3A2,UGDH
hsa00970	Aminoacyl-tRNA biosynthesis	0.9904377491312	-0.00960826274262341	66	21	0.00692612137203166	3032	6715	79731,833,51520,10352,4677,57505,10667,7407,80222,6897,51067,54938,2058,5917,1615,55157,55699,23438,10056,123283,79587	NARS2,CARS,LARS,WARS2,NARS,AARS2,FARS2,VARS,TARS2,TARS,YARS2,SARS2,EPRS,RARS,DARS,DARS2,IARS2,HARS2,FARSB,TARSL2,CARS2
ko00970	Aminoacyl-tRNA biosynthesis	0.9904377491312	-0.00960826274262341	66	21	0.00692612137203166	3032	6715	79731,833,51520,10352,4677,57505,10667,7407,80222,6897,51067,54938,5917,2058,1615,55699,55157,23438,10056,123283,79587	NARS2,CARS,LARS,WARS2,NARS,AARS2,FARS2,VARS,TARS2,TARS,YARS2,SARS2,RARS,EPRS,DARS,IARS2,DARS2,HARS2,FARSB,TARSL2,CARS2
M00104	Bile acid biosynthesis, cholesterol => cholate	0.991981122320553	-0.00805120179713326	12	2	0.000659630606860158	3032	6715	3295,80270	HSD17B4,HSD3B7
hsa_M00104	Bile acid biosynthesis, cholesterol => cholate	0.991981122320553	-0.00805120179713326	12	2	0.000659630606860158	3032	6715	3295,80270	HSD17B4,HSD3B7
ko00860	Porphyrin and chlorophyll metabolism	0.99351576797975	-0.00650534597403615	43	12	0.00395778364116095	3032	6715	2058,7363,210,7390,645,94033,54578,3145,5498,1352,3162,326625	EPRS,UGT2B4,ALAD,UROS,BLVRB,FTMT,UGT1A6,HMBS,PPOX,COX10,HMOX1,MMAB
hsa00860	Porphyrin and chlorophyll metabolism	0.99351576797975	-0.00650534597403615	43	12	0.00395778364116095	3032	6715	2058,7363,210,7390,645,94033,54578,3145,5498,3162,1352,326625	EPRS,UGT2B4,ALAD,UROS,BLVRB,FTMT,UGT1A6,HMBS,PPOX,HMOX1,COX10,MMAB
hsa00983	Drug metabolism - other enzymes	0.993940546056343	-0.00607788693500202	46	13	0.00428759894459103	3032	6715	1890,7363,54963,1548,7378,1807,7371,1066,3614,54578,83549,8833,7084	TYMP,UGT2B4,UCKL1,CYP2A6,UPP1,DPYS,UCK2,CES1,IMPDH1,UGT1A6,UCK1,GMPS,TK2
ko00983	Drug metabolism - other enzymes	0.993940546056343	-0.00607788693500202	46	13	0.00428759894459103	3032	6715	1890,7363,54963,1548,7378,1807,7371,1066,3614,54578,8833,83549,7084	TYMP,UGT2B4,UCKL1,CYP2A6,UPP1,DPYS,UCK2,CES1,IMPDH1,UGT1A6,GMPS,UCK1,TK2
hsa00650	Butanoate metabolism	0.994549786682112	-0.00546511991793126	26	6	0.00197889182058048	3032	6715	79944,35,3157,3033,64064,622	L2HGDH,ACADS,HMGCS1,HADH,OXCT2,BDH1
ko00650	Butanoate metabolism	0.994549786682112	-0.00546511991793126	26	6	0.00197889182058048	3032	6715	35,79944,3157,3033,64064,622	ACADS,L2HGDH,HMGCS1,HADH,OXCT2,BDH1
hsa04940	Type I diabetes mellitus	0.995618490228556	-0.00439113671604183	47	13	0.00428759894459103	3032	6715	3123,3113,3382,942,356,5799,3107,1363,5551,940,3630,3105,355	HLA-DRB1,HLA-DPA1,ICA1,CD86,FASLG,PTPRN2,HLA-C,CPE,PRF1,CD28,INS,HLA-A,FAS
ko04940	Type I diabetes mellitus	0.995618490228556	-0.00439113671604183	47	13	0.00428759894459103	3032	6715	3123,3113,3382,942,356,5799,3107,1363,5551,940,3630,3105,355	HLA-DRB1,HLA-DPA1,ICA1,CD86,FASLG,PTPRN2,HLA-C,CPE,PRF1,CD28,INS,HLA-A,FAS
ko00120	Primary bile acid biosynthesis	0.996094101584638	-0.00391354635779762	17	3	0.000989445910290238	3032	6715	3295,10858,80270	HSD17B4,CYP46A1,HSD3B7
hsa00120	Primary bile acid biosynthesis	0.996094101584638	-0.00391354635779762	17	3	0.000989445910290238	3032	6715	3295,10858,80270	HSD17B4,CYP46A1,HSD3B7
hsa04060	Cytokine-cytokine receptor interaction	0.997515573977742	-0.00248751732973234	265	98	0.0323218997361478	3032	6715	90,3601,3600,6375,27242,943,1270,3596,29949,53833,3606,7173,6361,1441,5154,3572,11009,3566,4233,7293,3815,3588,3556,5159,3562,3976,56477,115650,84957,23529,8743,3578,3586,7422,80301,10913,1233,2321,3576,7132,9547,4254,3082,4982,657,7292,8793,8995,1236,57007,3565,7046,8718,944,7042,4352,55504,7048,50615,2688,23495,650,4055,8771,1440,3625,6846,2324,5618,268,6351,51330,3952,8792,56034,3590,2057,3460,6364,27190,3570,1437,3454,3560,2323,4804,1956,355,3554,1435,356,9180,50604,3581,3567,1234,6370,1436	ACVR1,IL15RA,IL15,XCL1,TNFRSF21,TNFRSF8,CNTF,IL13,IL19,IL20RB,IL18,TPO,CCL17,CSF3R,PDGFA,IL6ST,IL24,IL4R,MET,TNFRSF4,KIT,IL10RB,IL1RAP,PDGFRB,IL3,LIF,CCL28,TNFRSF13C,RELT,CLCF1,TNFSF10,IL9,IL10,VEGFA,PLEKHO2,EDAR,CCR4,FLT1,IL8,TNFRSF1A,CXCL14,KITLG,HGF,TNFRSF11B,BMPR1A,TNFSF4,TNFRSF10D,TNFSF18,CCR7,ACKR3,IL4,TGFBR1,TNFRSF25,TNFSF8,TGFB2,MPL,TNFRSF19,TGFBR2,IL21R,GH1,TNFRSF13B,BMP2,LTBR,TNFRSF6B,CSF3,INHBB,XCL2,FLT4,PRLR,AMH,CCL4,TNFRSF12A,LEP,TNFRSF11A,PDGFC,IL11RA,EPOR,IFNGR2,CCL20,IL17B,IL6R,CSF2,IFNAR1,IL2RB,FLT3LG,NGFR,EGFR,FAS,IL1R1,CSF1,FASLG,OSMR,IL20,IL9R,IL5,CCR5,CCL25,CSF1R
ko04060	Cytokine-cytokine receptor interaction	0.997515573977742	-0.00248751732973234	265	98	0.0323218997361478	3032	6715	90,3601,3600,6375,27242,943,1270,3596,29949,53833,3606,7173,6361,1441,5154,3572,11009,3566,4233,7293,3815,3588,3556,5159,3562,3976,56477,115650,84957,23529,8743,3578,3586,7422,80301,10913,1233,2321,3576,7132,9547,4254,3082,4982,657,7292,8793,8995,1236,57007,3565,7046,8718,944,7042,4352,55504,7048,50615,2688,23495,650,4055,8771,1440,3625,6846,2324,5618,268,6351,51330,3952,8792,56034,3590,2057,3460,6364,27190,3570,1437,3454,3560,2323,4804,1956,355,3554,1435,356,9180,50604,3581,3567,1234,6370,1436	ACVR1,IL15RA,IL15,XCL1,TNFRSF21,TNFRSF8,CNTF,IL13,IL19,IL20RB,IL18,TPO,CCL17,CSF3R,PDGFA,IL6ST,IL24,IL4R,MET,TNFRSF4,KIT,IL10RB,IL1RAP,PDGFRB,IL3,LIF,CCL28,TNFRSF13C,RELT,CLCF1,TNFSF10,IL9,IL10,VEGFA,PLEKHO2,EDAR,CCR4,FLT1,IL8,TNFRSF1A,CXCL14,KITLG,HGF,TNFRSF11B,BMPR1A,TNFSF4,TNFRSF10D,TNFSF18,CCR7,ACKR3,IL4,TGFBR1,TNFRSF25,TNFSF8,TGFB2,MPL,TNFRSF19,TGFBR2,IL21R,GH1,TNFRSF13B,BMP2,LTBR,TNFRSF6B,CSF3,INHBB,XCL2,FLT4,PRLR,AMH,CCL4,TNFRSF12A,LEP,TNFRSF11A,PDGFC,IL11RA,EPOR,IFNGR2,CCL20,IL17B,IL6R,CSF2,IFNAR1,IL2RB,FLT3LG,NGFR,EGFR,FAS,IL1R1,CSF1,FASLG,OSMR,IL20,IL9R,IL5,CCR5,CCL25,CSF1R
M00426	Survival motor neuron (SMN) complex	0.997550046348965	-0.00245295969826884	10	1	0.000329815303430079	3032	6715	25929	GEMIN5
hsa_M00426	Survival motor neuron (SMN) complex	0.997550046348965	-0.00245295969826884	10	1	0.000329815303430079	3032	6715	25929	GEMIN5
hsa05204	Chemical carcinogenesis	0.99915501143032	-0.000845345773757903	80	23	0.00758575197889182	3032	6715	1139,7363,4259,56267,2950,6818,222,653689,5743,221,883,873,119391,1646,3290,1548,220,218,54578,2941,445329,405,2052	CHRNA7,UGT2B4,MGST3,CCBL2,GSTP1,SULT1A3,ALDH3B2,GSTT2B,PTGS2,ALDH3B1,CCBL1,CBR1,GSTO2,AKR1C2,HSD11B1,CYP2A6,ALDH1A3,ALDH3A1,UGT1A6,GSTA4,SULT1A4,ARNT,EPHX1
ko05204	Chemical carcinogenesis	0.99915501143032	-0.000845345773757903	80	23	0.00758575197889182	3032	6715	1139,7363,4259,56267,2950,6818,222,653689,5743,221,883,873,119391,1646,3290,1548,220,218,54578,2941,445329,405,2052	CHRNA7,UGT2B4,MGST3,CCBL2,GSTP1,SULT1A3,ALDH3B2,GSTT2B,PTGS2,ALDH3B1,CCBL1,CBR1,GSTO2,AKR1C2,HSD11B1,CYP2A6,ALDH1A3,ALDH3A1,UGT1A6,GSTA4,SULT1A4,ARNT,EPHX1
hsa05320	Autoimmune thyroid disease	0.999459248173117	-0.00054089808588132	56	14	0.00461741424802111	3032	6715	3123,3113,942,3565,356,7038,7173,3586,3107,5551,940,3567,3105,355	HLA-DRB1,HLA-DPA1,CD86,IL4,FASLG,TG,TPO,IL10,HLA-C,PRF1,CD28,IL5,HLA-A,FAS
ko05320	Autoimmune thyroid disease	0.999459248173117	-0.00054089808588132	56	14	0.00461741424802111	3032	6715	3123,3113,942,3565,356,7038,7173,3586,3107,5551,940,3567,3105,355	HLA-DRB1,HLA-DPA1,CD86,IL4,FASLG,TG,TPO,IL10,HLA-C,PRF1,CD28,IL5,HLA-A,FAS
ko00982	Drug metabolism - cytochrome P450	0.999540881736541	-0.000459223690519332	68	18	0.00593667546174142	3032	6715	7363,1565,2326,4259,2950,222,653689,221,119391,2327,2329,1548,220,218,4128,54578,2941,2328	UGT2B4,CYP2D6,FMO1,MGST3,GSTP1,ALDH3B2,GSTT2B,ALDH3B1,GSTO2,FMO2,FMO4,CYP2A6,ALDH1A3,ALDH3A1,MAOA,UGT1A6,GSTA4,FMO3
hsa00982	Drug metabolism - cytochrome P450	0.999540881736541	-0.000459223690519332	68	18	0.00593667546174142	3032	6715	7363,1565,2326,4259,2950,222,653689,221,119391,2327,2329,1548,220,218,4128,54578,2941,2328	UGT2B4,CYP2D6,FMO1,MGST3,GSTP1,ALDH3B2,GSTT2B,ALDH3B1,GSTO2,FMO2,FMO4,CYP2A6,ALDH1A3,ALDH3A1,MAOA,UGT1A6,GSTA4,FMO3
hsa00980	Metabolism of xenobiotics by cytochrome P450	0.999588991166174	-0.00041109332110751	74	20	0.00659630606860158	3032	6715	7363,1565,4259,2950,222,653689,27294,221,873,119391,1646,22977,3290,1548,220,218,54578,2941,8574,2052	UGT2B4,CYP2D6,MGST3,GSTP1,ALDH3B2,GSTT2B,DHDH,ALDH3B1,CBR1,GSTO2,AKR1C2,AKR7A3,HSD11B1,CYP2A6,ALDH1A3,ALDH3A1,UGT1A6,GSTA4,AKR7A2,EPHX1
ko00980	Metabolism of xenobiotics by cytochrome P450	0.999588991166174	-0.00041109332110751	74	20	0.00659630606860158	3032	6715	7363,1565,4259,2950,222,653689,27294,221,873,1646,119391,22977,3290,1548,220,218,54578,2941,8574,2052	UGT2B4,CYP2D6,MGST3,GSTP1,ALDH3B2,GSTT2B,DHDH,ALDH3B1,CBR1,AKR1C2,GSTO2,AKR7A3,HSD11B1,CYP2A6,ALDH1A3,ALDH3A1,UGT1A6,GSTA4,AKR7A2,EPHX1
ko05332	Graft-versus-host disease	0.999623374400555	-0.000376696540678785	45	10	0.00329815303430079	3032	6715	3123,3113,942,356,3107,5551,940,3105,355,3802	HLA-DRB1,HLA-DPA1,CD86,FASLG,HLA-C,PRF1,CD28,HLA-A,FAS,KIR2DL1
hsa05332	Graft-versus-host disease	0.999623374400555	-0.000376696540678785	45	10	0.00329815303430079	3032	6715	3123,3113,942,356,3107,5551,940,3105,355,3802	HLA-DRB1,HLA-DPA1,CD86,FASLG,HLA-C,PRF1,CD28,HLA-A,FAS,KIR2DL1
hsa05322	Systemic lupus erythematosus	0.999872559901383	-0.000127448219796094	138	42	0.0138522427440633	3032	6715	126961,942,729,8349,8358,88,8970,8290,317772,440689,3123,713,3113,6632,2209,714,9555,653604,3017,92815,718,8336,8370,6628,85236,3021,87,3586,2214,733,158983,712,2212,81,8337,3020,8338,128312,6738,940,286436,333932	HIST2H3C,CD86,C6,HIST2H2BE,HIST1H3B,ACTN2,HIST1H2BJ,HIST3H3,HIST2H2AB,HIST2H2BF,HLA-DRB1,C1QB,HLA-DPA1,SNRPD1,FCGR1A,C1QC,H2AFY,HIST2H3D,HIST1H2BD,HIST3H2A,C3,HIST1H2AM,HIST2H4A,SNRPB,HIST1H2BK,H3F3B,ACTN1,IL10,FCGR3A,C8G,H2BFWT,C1QA,FCGR2A,ACTN4,HIST2H2AA3,H3F3A,HIST2H2AC,HIST3H2BB,TROVE2,CD28,H2BFM,HIST2H3A
ko05322	Systemic lupus erythematosus	0.999872559901383	-0.000127448219796094	138	42	0.0138522427440633	3032	6715	126961,942,729,8349,8358,88,8970,8290,317772,440689,3123,713,3113,6632,2209,714,9555,653604,3017,92815,718,8336,8370,6628,85236,3021,87,3586,2214,733,158983,712,2212,81,8337,3020,8338,128312,6738,940,286436,333932	HIST2H3C,CD86,C6,HIST2H2BE,HIST1H3B,ACTN2,HIST1H2BJ,HIST3H3,HIST2H2AB,HIST2H2BF,HLA-DRB1,C1QB,HLA-DPA1,SNRPD1,FCGR1A,C1QC,H2AFY,HIST2H3D,HIST1H2BD,HIST3H2A,C3,HIST1H2AM,HIST2H4A,SNRPB,HIST1H2BK,H3F3B,ACTN1,IL10,FCGR3A,C8G,H2BFWT,C1QA,FCGR2A,ACTN4,HIST2H2AA3,H3F3A,HIST2H2AC,HIST3H2BB,TROVE2,CD28,H2BFM,HIST2H3A
hsa00830	Retinol metabolism	0.999991957033329	-8.04299901626788e-06	64	13	0.00428759894459103	3032	6715	56603,728635,54884,7363,1548,5959,157506,54578,8630,8694,9249,9227,1592	CYP26B1,DHRS4L1,RETSAT,UGT2B4,CYP2A6,RDH5,RDH10,UGT1A6,HSD17B6,DGAT1,DHRS3,LRAT,CYP26A1
ko00830	Retinol metabolism	0.999991957033329	-8.04299901626788e-06	64	13	0.00428759894459103	3032	6715	728635,56603,54884,7363,1548,157506,5959,54578,8630,8694,9249,9227,1592	DHRS4L1,CYP26B1,RETSAT,UGT2B4,CYP2A6,RDH10,RDH5,UGT1A6,HSD17B6,DGAT1,DHRS3,LRAT,CYP26A1
hsa04740	Olfactory transduction	0.999999999880569	-1.19431454394043e-10	405	82	0.0270448548812665	3032	6715	343406,343563,26693,5137,338662,440153,5566,26683,283694,4992,391196,403239,127064,401993,26476,26245,127062,109,283092,343171,815,5567,391192,391194,343169,285659,8386,26682,5613,81399,127074,343173,817,284532,26188,391114,402317,144124,81466,119749,403257,401427,127059,441308,2774,284383,284521,343172,504191,391211,81469,79541,390199,51806,3000,127068,81061,441933,5593,254879,504189,2978,127066,81472,818,401992,256144,81470,391189,26696,127623,127385,441911,391191,81448,391195,816,163688,346528,401994,810,143496	OR10R2,OR2T29,OR2V1,PDE1C,OR8D4,OR11H12,PRKACA,OR4F3,OR4N4,OR1F1,OR2M7,OR2T27,OR2T12,OR2T5,OR10J1,OR2M4,OR2M3,ADCY3,OR4C13,OR2W3,CAMK2A,PRKACB,OR2L3,OR2M2,OR6F1,OR2V2,OR1D5,OR4F4,PRKX,OR4F16,OR2T4,OR2T3,CAMK2D,OR14A16,OR1C1,OR6K3,OR2A42,OR10A5,OR2L5,OR4C46,OR4C45,OR2A7,OR2M5,OR4F21,GNAL,OR2Z1,OR2L13,OR2T8,OR9G9,OR2G6,OR2G3,OR2A4,OR4D9,CALML5,GUCY2D,OR2T34,OR11H1,OR13G1,PRKG2,OR2T6,OR8U8,GUCA1A,OR14C36,OR2C3,CAMK2G,OR2T2,OR4C3,OR2G2,OR11L1,OR2T1,OR2B11,OR10J5,OR10J3,OR2AK2,OR6K2,OR2T33,CAMK2B,CALML6,OR2A1,OR14I1,CALML3,OR52B4
ko04740	Olfactory transduction	0.999999999880569	-1.19431454394043e-10	405	82	0.0270448548812665	3032	6715	343406,343563,26693,5137,338662,440153,5566,26683,283694,4992,391196,403239,127064,401993,26476,26245,127062,109,283092,343171,815,5567,391192,391194,343169,285659,8386,26682,5613,81399,127074,343173,817,284532,26188,391114,402317,144124,81466,119749,403257,401427,127059,441308,2774,284383,284521,343172,504191,391211,81469,79541,390199,51806,3000,127068,81061,441933,5593,254879,504189,2978,127066,81472,818,401992,256144,81470,391189,26696,127623,127385,441911,391191,81448,391195,816,163688,346528,401994,810,143496	OR10R2,OR2T29,OR2V1,PDE1C,OR8D4,OR11H12,PRKACA,OR4F3,OR4N4,OR1F1,OR2M7,OR2T27,OR2T12,OR2T5,OR10J1,OR2M4,OR2M3,ADCY3,OR4C13,OR2W3,CAMK2A,PRKACB,OR2L3,OR2M2,OR6F1,OR2V2,OR1D5,OR4F4,PRKX,OR4F16,OR2T4,OR2T3,CAMK2D,OR14A16,OR1C1,OR6K3,OR2A42,OR10A5,OR2L5,OR4C46,OR4C45,OR2A7,OR2M5,OR4F21,GNAL,OR2Z1,OR2L13,OR2T8,OR9G9,OR2G6,OR2G3,OR2A4,OR4D9,CALML5,GUCY2D,OR2T34,OR11H1,OR13G1,PRKG2,OR2T6,OR8U8,GUCA1A,OR14C36,OR2C3,CAMK2G,OR2T2,OR4C3,OR2G2,OR11L1,OR2T1,OR2B11,OR10J5,OR10J3,OR2AK2,OR6K2,OR2T33,CAMK2B,CALML6,OR2A1,OR14I1,CALML3,OR52B4
hsa00290	Valine, leucine and isoleucine biosynthesis	0.999999999980693	-1.93065285980509e-11	2	0	0	3032	6715
ko00290	Valine, leucine and isoleucine biosynthesis	0.999999999980693	-1.93065285980509e-11	2	0	0	3032	6715
M00293	DNA polymerase zeta  complex	0.999999999980693	-1.93065285980509e-11	2	0	0	3032	6715
hsa_M00066	Lactosylceramide biosynthesis	0.999999999980693	-1.93065285980509e-11	2	0	0	3032	6715
M00106	Conjugated bile acid biosynthesis, cholate => taurocholate/glycocholate	0.999999999980693	-1.93065285980509e-11	2	0	0	3032	6715
M00066	Lactosylceramide biosynthesis	0.999999999980693	-1.93065285980509e-11	2	0	0	3032	6715
M00067	Cerebroside and sulfatide biosynthesis	0.999999999980693	-1.93065285980509e-11	2	0	0	3032	6715
hsa_M00067	Cerebroside and sulfatide biosynthesis	0.999999999980693	-1.93065285980509e-11	2	0	0	3032	6715
hsa_M00293	DNA polymerase zeta  complex	0.999999999980693	-1.93065285980509e-11	2	0	0	3032	6715
hsa_M00106	Conjugated bile acid biosynthesis, cholate => taurocholate/glycocholate	0.999999999980693	-1.93065285980509e-11	2	0	0	3032	6715
ko00785	Lipoic acid metabolism	0.999999999985375	-1.46251344368409e-11	3	0	0	3032	6715
hsa00780	Biotin metabolism	0.999999999985375	-1.46251344368409e-11	3	0	0	3032	6715
ko01220	Degradation of aromatic compounds	0.999999999985375	-1.46251344368409e-11	3	0	0	3032	6715
hsa01220	Degradation of aromatic compounds	0.999999999985375	-1.46251344368409e-11	3	0	0	3032	6715
hsa00785	Lipoic acid metabolism	0.999999999985375	-1.46251344368409e-11	3	0	0	3032	6715
M00005	PRPP biosynthesis, ribose 5P => PRPP	0.999999999985375	-1.46251344368409e-11	3	0	0	3032	6715
ko00780	Biotin metabolism	0.999999999985375	-1.46251344368409e-11	3	0	0	3032	6715
hsa_M00118	Glutathione biosynthesis, glutamate => glutathione	0.999999999985375	-1.46251344368409e-11	3	0	0	3032	6715
M00118	Glutathione biosynthesis, glutamate => glutathione	0.999999999985375	-1.46251344368409e-11	3	0	0	3032	6715
hsa_M00005	PRPP biosynthesis, ribose 5P => PRPP	0.999999999985375	-1.46251344368409e-11	3	0	0	3032	6715
hsa_M00027	GABA (gamma-Aminobutyrate) shunt	0.999999999986451	-1.35488009700424e-11	4	0	0	3032	6715
M00027	GABA (gamma-Aminobutyrate) shunt	0.999999999986451	-1.35488009700424e-11	4	0	0	3032	6715
M00079	Keratan sulfate degradation	0.999999999991222	-8.77752731609505e-12	5	0	0	3032	6715
hsa_M00079	Keratan sulfate degradation	0.999999999991222	-8.77752731609505e-12	5	0	0	3032	6715
M00142	NADH:ubiquinone oxidoreductase, mitochondria	1.00000000000261	2.61069204449127e-12	7	0	0	3032	6715
hsa_M00142	NADH:ubiquinone oxidoreductase, mitochondria	1.00000000000261	2.61069204449127e-12	7	0	0	3032	6715