TermID	Term	Enrichment	logP	Genes in Term	Target Genes in Term	Fraction of Targets in Term	Total Target Genes	Total Genes	Entrez Gene IDs	Gene Symbols
p38alphabetadownstreampathway	Signaling mediated by p38-alpha and p38-beta	0.000160404468739328	-8.73781200294907	35	29	0.0246598639455782	1176	2242	2005,5321,3856,7867,8550,5868,4205,9252,1432,1051,3725,9261,26959,5743,7391,1978,4286,6548,5600,22926,8986,3880,1385,1386,3315,1977,4843,1649,4208	ELK4,PLA2G4A,KRT8,MAPKAPK3,MAPKAPK5,RAB5A,MEF2A,RPS6KA5,MAPK14,CEBPB,JUN,MAPKAPK2,HBP1,PTGS2,USF1,EIF4EBP1,MITF,SLC9A1,MAPK11,ATF6,RPS6KA4,KRT19,CREB1,ATF2,HSPB1,EIF4E,NOS2,DDIT3,MEF2C
hif1_tfpathway	HIF-1-alpha transcription factor network	0.000734604451717518	-7.21617836454055	65	47	0.0399659863945578	1176	2242	7033,10397,6513,3398,4869,8553,2113,3162,7037,2022,3725,5211,79365,51564,3952,664,1385,2023,10499,6667,4907,5236,207,3484,1906,3939,5045,5209,4170,7422,5315,2353,3689,4088,2645,5230,7015,3091,226,3099,5054,3098,3172,4843,4089,405,54583	TFF3,NDRG1,SLC2A1,ID2,NPM1,BHLHE40,ETS1,HMOX1,TFRC,ENG,JUN,PFKL,BHLHE41,HDAC7,LEP,BNIP3,CREB1,ENO1,NCOA2,SP1,NT5E,PGM1,AKT1,IGFBP1,EDN1,LDHA,FURIN,PFKFB3,MCL1,VEGFA,PKM,FOS,ITGB2,SMAD3,GCK,PGK1,TERT,HIF1A,ALDOA,HK2,SERPINE1,HK1,HNF4A,NOS2,SMAD4,ARNT,EGLN1
wnt_canonical_pathway	Canonical Wnt signaling pathway	0.00546680123008478	-5.20906161786363	30	23	0.0195578231292517	1176	2242	23291,1454,8452,85409,324,857,1452,8498,55361,5515,1499,5518,8312,53944,6500,2932,1855,7855,89780,59349,8945,1453,1856	FBXW11,CSNK1E,CUL3,NKD2,APC,CAV1,CSNK1A1,RANBP3,PI4K2A,PPP2CA,CTNNB1,PPP2R1A,AXIN1,CSNK1G1,SKP1,GSK3B,DVL1,FZD5,WNT3A,KLHL12,BTRC,CSNK1D,DVL2
p38_mk2pathway	p38 signaling mediated by MAPKAP kinases	0.0103997233005164	-4.56597607890833	20	16	0.0136054421768707	1176	2242	7249,7867,5894,6929,10971,7531,1432,9261,6722,7534,4046,994,1385,3315,2115,2810	TSC2,MAPKAPK3,RAF1,TCF3,YWHAQ,YWHAE,MAPK14,MAPKAPK2,SRF,YWHAZ,LSP1,CDC25B,CREB1,HSPB1,ETV1,SFN
rhoa_reg_pathway	Regulation of RhoA activity	0.013078516459308	-4.33678435992788	46	32	0.0272108843537415	1176	2242	398,10160,64411,9826,7204,7410,10395,4650,55160,7409,23263,9138,7984,57522,9181,23779,613,23370,10451,64283,9639,1894,84033,23365,11214,29,55200,64333,116985,396,393,50619	ARHGDIG,FARP1,ARAP3,ARHGEF11,TRIO,VAV2,DLC1,MYO9B,ARHGEF10L,VAV1,MCF2L,ARHGEF1,ARHGEF5,SRGAP1,ARHGEF2,ARHGAP8,BCR,ARHGEF18,VAV3,ARHGEF28,ARHGEF10,ECT2,OBSCN,ARHGEF12,AKAP13,ABR,PLEKHG6,ARHGAP9,ARAP1,ARHGDIA,ARHGAP4,DEF6
lysophospholipid_pathway	LPA receptor mediated events	0.0163874907353556	-4.11123699524073	65	43	0.0365646258503401	1176	2242	4318,9170,1839,7205,2769,2782,5338,4067,6714,23566,9351,5331,147,3725,2781,4313,5580,9138,4790,112,109,2771,7074,113,5829,207,5295,107,5747,2353,9564,2767,1956,9630,2768,5335,111,114,4792,3576,2932,2185,3265	MMP9,LPAR2,HBEGF,TRIP6,GNA15,GNB1,PLD2,LYN,SRC,LPAR3,SLC9A3R2,PLCB3,ADRA1B,JUN,GNAZ,MMP2,PRKCD,ARHGEF1,NFKB1,ADCY6,ADCY3,GNAI2,TIAM1,ADCY7,PXN,AKT1,PIK3R1,ADCY1,PTK2,FOS,BCAR1,GNA11,EGFR,GNA14,GNA12,PLCG1,ADCY5,ADCY8,NFKBIA,IL8,GSK3B,PTK2B,HRAS
wnt_beta_catenin_pathway	Regulation of Wnt-mediated beta catenin signaling and target gene transcription	0.0182447657187951	-4.00387705002051	79	51	0.0433673469387755	1176	2242	4318,4656,3398,6597,166,324,7531,56998,595,3725,26959,6862,999,1499,57680,170261,3491,4609,4286,4313,29969,1044,10499,4762,6591,113,7089,7091,79718,2249,607,10971,6932,6934,22943,5308,83439,7514,7015,9314,1462,3576,6500,7088,7534,6907,3619,1487,8945,3066,2810	MMP9,MYOG,ID2,SMARCA4,AES,APC,YWHAE,CTNNBIP1,CCND1,JUN,HBP1,T,CDH1,CTNNB1,CHD8,ZCCHC12,CYR61,MYC,MITF,MMP2,MDFIC,CDX1,NCOA2,NEUROG1,SNAI2,ADCY7,TLE2,TLE4,TBL1XR1,FGF4,BCL9,YWHAQ,TCF7,TCF7L2,DKK1,PITX2,TCF7L1,XPO1,TERT,KLF4,VCAN,IL8,SKP1,TLE1,YWHAZ,TBL1X,INCENP,CTBP1,BTRC,HDAC2,SFN
ephrinb_ephbpathway	EphrinB-EPHB pathway	0.0207009445062579	-3.87757595143012	6	6	0.00510204081632653	1176	2242	1948,2050,2048,2047,1947,2049	EFNB2,EPHB4,EPHB2,EPHB1,EFNB1,EPHB3
pdgfrbpathway	PDGFR-beta signaling pathway	0.0230506649415258	-3.77006066216703	54	36	0.0306122448979592	1176	2242	6461,7410,29907,8877,6503,4067,6714,9351,25,640,5770,6464,4609,5580,5781,5290,1785,6774,5159,2241,207,4690,5295,867,9564,5335,2268,5795,2534,3091,10603,2886,52,6776,2887,3265	SHB,VAV2,SNX15,SPHK1,SLA,LYN,SRC,SLC9A3R2,ABL1,BLK,PTPN1,SHC1,MYC,PRKCD,PTPN11,PIK3CA,DNM2,STAT3,PDGFRB,FER,AKT1,NCK1,PIK3R1,CBL,BCAR1,PLCG1,FGR,PTPRJ,FYN,HIF1A,SH2B2,GRB7,ACP1,STAT5A,GRB10,HRAS
a6b1_a6b4_integrin_pathway	a6b1 and a6b4 Integrin signaling	0.0274954146514583	-3.59373602815923	31	22	0.0187074829931973	1176	2242	207,3655,5295,10971,2064,7531,5578,4485,1956,6464,999,4486,928,5290,3688,6198,7534,2065,3691,4233,3265,2810	AKT1,ITGA6,PIK3R1,YWHAQ,ERBB2,YWHAE,PRKCA,MST1,EGFR,SHC1,CDH1,MST1R,CD9,PIK3CA,ITGB1,RPS6KB1,YWHAZ,ERBB3,ITGB4,MET,HRAS,SFN
p53regulationpathway	p53 pathway	0.0288788397498178	-3.54464614063235	58	38	0.032312925170068	1176	2242	7874,63970,8850,8493,4194,11186,1111,1452,1432,1877,6135,25,387893,5300,5580,5601,545,10419,1456,84148,1455,207,1454,900,80854,56950,10155,64326,80204,5515,1616,53944,28996,472,2932,10848,7528,1453	USP7,TP53AIP1,KAT2B,PPM1D,MDM4,RASSF1,CHEK1,CSNK1A1,MAPK14,E4F1,RPL11,ABL1,SETD8,PIN1,PRKCD,MAPK9,ATR,PRMT5,CSNK1G3,KAT8,CSNK1G2,AKT1,CSNK1E,CCNG1,SETD7,SMYD2,TRIM28,RFWD2,FBXO11,PPP2CA,DAXX,CSNK1G1,HIPK2,ATM,GSK3B,PPP1R13L,YY1,CSNK1D
epha2_fwdpathway	EPHA2 forward signaling	0.0380543893761585	-3.26873884321576	17	13	0.0110544217687075	1176	2242	5058,10451,3636,1969,5295,7410,5290,52,1942,867,9564,7074,6714	PAK1,VAV3,INPPL1,EPHA2,PIK3R1,VAV2,PIK3CA,ACP1,EFNA1,CBL,BCAR1,TIAM1,SRC
cd40_pathway	CD40/CD40L signaling	0.0383613132031917	-3.26070579589301	30	21	0.0178571428571429	1176	2242	7189,7128,207,330,7186,3565,868,1432,329,3725,7185,4609,4790,5601,4792,6776,5600,7187,83953,9020,722	TRAF6,TNFAIP3,AKT1,BIRC3,TRAF2,IL4,CBLB,MAPK14,BIRC2,JUN,TRAF1,MYC,NFKB1,MAPK9,NFKBIA,STAT5A,MAPK11,TRAF3,FCAMR,MAP3K14,C4BPA
mtor_4pathway	mTOR signaling pathway	0.0447047496524631	-3.10767552680018	61	39	0.0331632653061225	1176	2242	23291,7249,2475,5894,6195,79109,5338,54205,7531,5578,898,54541,29904,57521,3551,6720,6446,664,55615,1977,64223,5170,5829,1975,207,9821,64798,10971,1973,5605,6009,1978,7534,6198,5337,7528,8945,27250,2810	FBXW11,TSC2,MTOR,RAF1,RPS6KA1,MAPKAP1,PLD2,CYCS,YWHAE,PRKCA,CCNE1,DDIT4,EEF2K,RPTOR,IKBKB,SREBF1,SGK1,BNIP3,PRR5,EIF4E,MLST8,PDPK1,PXN,EIF4B,AKT1,RB1CC1,DEPTOR,YWHAQ,EIF4A1,MAP2K2,RHEB,EIF4EBP1,YWHAZ,RPS6KB1,PLD1,YY1,BTRC,PDCD4,SFN
plk1_pathway	PLK1 signaling events	0.0482327330836145	-3.03171737879762	44	29	0.0246598639455782	1176	2242	5058,23291,10112,4659,63967,991,1894,22974,701,5861,891,995,983,79682,26271,3796,5515,7465,2801,22981,5518,51343,147841,699,994,151648,3619,8945,10726	PAK1,FBXW11,KIF20A,PPP1R12A,CLSPN,CDC20,ECT2,TPX2,BUB1B,RAB1A,CCNB1,CDC25C,CDK1,CENPU,FBXO5,KIF2A,PPP2CA,WEE1,GOLGA2,NINL,PPP2R1A,FZR1,SPC24,BUB1,CDC25B,SGOL1,INCENP,BTRC,NUDC
vegfr1_2_pathway	Signaling events mediated by VEGFR1 and VEGFR2	0.0485748150064177	-3.02465009213726	63	40	0.0340136054421769	1176	2242	6461,2034,5578,5566,6714,8828,25759,5606,6464,1499,2324,5781,5290,5600,3320,7414,2242,5170,5058,5829,207,4690,9047,5777,5295,857,7422,5335,2534,3091,1003,2321,2185,2887,3685,6093,8829,3315,3265,405	SHB,EPAS1,PRKCA,PRKACA,SRC,NRP2,SHC2,MAP2K3,SHC1,CTNNB1,FLT4,PTPN11,PIK3CA,MAPK11,HSP90AA1,VCL,FES,PDPK1,PAK1,PXN,AKT1,NCK1,SH2D2A,PTPN6,PIK3R1,CAV1,VEGFA,PLCG1,FYN,HIF1A,CDH5,FLT1,PTK2B,GRB10,ITGAV,ROCK1,NRP1,HSPB1,HRAS,ARNT
p53downstreampathway	Direct p53 effectors	0.0497505606282991	-3.00073354653049	134	80	0.0680272108843537	1176	2242	5564,7249,10397,3732,6890,80781,6597,324,1026,891,637,3303,7161,5111,5366,55240,7159,4233,64065,6591,5458,10498,3486,7306,3976,1263,578,255488,7832,7039,467,4170,857,27244,9540,7421,1907,4800,1969,54487,27113,3082,5054,8793,3066,839,3276,9518,6273,1847,133746,54541,3725,8812,57103,2232,4313,1509,25946,6667,1843,1643,28984,3090,900,1820,1956,22943,3304,355,64326,1647,50484,1462,7027,1655,317,55800,2876,2810	PRKAB1,TSC2,NDRG1,CD82,TAP1,COL18A1,SMARCA4,APC,CDKN1A,CCNB1,BID,HSPA1A,TP73,PCNA,PMAIP1,STEAP3,TP53BP2,MET,PERP,SNAI2,POU4F2,CARM1,IGFBP3,TYRP1,LIF,PLK3,BAK1,RNF144B,BTG2,TGFA,ATF3,MCL1,CAV1,SESN1,TP53I3,VDR,EDN2,NFYA,EPHA2,DGCR8,BBC3,HGF,SERPINE1,TNFRSF10D,HDAC2,CASP6,PRMT1,GDF15,S100A2,DUSP5,JMY,DDIT4,JUN,CCNK,C12orf5,FDXR,MMP2,CTSD,ZNF385A,SP1,DUSP1,DDB2,RGCC,HIC1,CCNG1,ARID3A,EGFR,DKK1,HSPA1B,FAS,RFWD2,GADD45A,RRM2B,VCAN,TFDP1,DDX5,APAF1,SCN3B,GPX1,SFN
met_pathway	Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)	0.0525000651039556	-2.94694086930998	72	45	0.038265306122449	1176	2242	3636,1958,2475,1495,5894,324,2113,6714,10298,200958,30011,3725,57521,1399,5770,1499,999,5781,5290,4233,1977,3837,64223,5058,5170,54453,2889,5829,57610,207,4690,5295,64798,5868,867,9564,5605,5335,9146,5795,1978,3082,3265,8650,50649	INPPL1,EGR1,MTOR,CTNNA1,RAF1,APC,ETS1,SRC,PAK4,MUC20,SH3KBP1,JUN,RPTOR,CRKL,PTPN1,CTNNB1,CDH1,PTPN11,PIK3CA,MET,EIF4E,KPNB1,MLST8,PAK1,PDPK1,RIN2,RAPGEF1,PXN,RANBP10,AKT1,NCK1,PIK3R1,DEPTOR,RAB5A,CBL,BCAR1,MAP2K2,PLCG1,HGS,PTPRJ,EIF4EBP1,HGF,HRAS,NUMB,ARHGEF4
smad2_3nuclearpathway	Regulation of nuclear SMAD2/3 signaling	0.0637083089467366	-2.75344028618613	78	48	0.0408163265306122	1176	2242	51588,860,4149,8850,6929,4092,2625,1026,25942,1482,6497,3725,145258,4609,55802,1385,1386,10499,6667,7709,7050,2648,3915,207,2908,1019,3312,8928,467,3586,2353,1051,10401,7421,4088,4087,5933,7027,51586,4654,3665,5054,4089,3172,1487,3567,3066,4208	PIAS4,RUNX2,MAX,KAT2B,TCF3,SMAD7,GATA3,CDKN1A,SIN3A,NKX2-5,SKI,JUN,GSC,MYC,DCP1A,CREB1,ATF2,NCOA2,SP1,ZBTB17,TGIF1,KAT2A,LAMC1,AKT1,NR3C1,CDK4,HSPA8,FOXH1,ATF3,IL10,FOS,CEBPB,PIAS3,VDR,SMAD3,SMAD2,RBL1,TFDP1,MED15,MYOD1,IRF7,SERPINE1,SMAD4,HNF4A,CTBP1,IL5,HDAC2,MEF2C
arf_3pathway	Arf1 pathway	0.0720104833034553	-2.63094356912806	18	13	0.0110544217687075	1176	2242	55738,8615,920,1314,50807,160,1211,5338,375,8394,1212,9266,8729	ARFGAP1,USO1,CD4,COPA,ASAP1,AP2A1,CLTA,PLD2,ARF1,PIP5K1A,CLTB,CYTH2,GBF1
igf1_pathway	IGF1 pathway	0.072114266392811	-2.62950338473901	28	19	0.016156462585034	1176	2242	5170,5829,207,5894,5295,10399,7531,9564,1399,5770,6464,5580,5290,5590,5781,7534,6198,2887,3265	PDPK1,PXN,AKT1,RAF1,PIK3R1,GNB2L1,YWHAE,BCAR1,CRKL,PTPN1,SHC1,PRKCD,PIK3CA,PRKCZ,PTPN11,YWHAZ,RPS6KB1,GRB10,HRAS
prlsignalingeventspathway	Signaling events mediated by PRL	0.0733546565780566	-2.61244929204478	23	16	0.0136054421768707	1176	2242	7803,1958,183,389,3688,11156,5876,1026,6093,3672,9564,6714,22809,898,5875,10376	PTP4A1,EGR1,AGT,RHOC,ITGB1,PTP4A3,RABGGTB,CDKN1A,ROCK1,ITGA1,BCAR1,SRC,ATF5,CCNE1,RABGGTA,TUBA1B
nfkappabcanonicalpathway	Canonical NF-kappaB pathway	0.0733546565780566	-2.61244929204478	23	16	0.0136054421768707	1176	2242	7323,8517,7189,7514,1540,7128,3551,4792,4790,10892,7132,64127,472,5578,329,8945	UBE2D3,IKBKG,TRAF6,XPO1,CYLD,TNFAIP3,IKBKB,NFKBIA,NFKB1,MALT1,TNFRSF1A,NOD2,ATM,PRKCA,BIRC2,BTRC
faspathway	FAS (CD95) signaling pathway	0.0779766171631556	-2.55134627719508	35	23	0.0195578231292517	1176	2242	5170,23017,5609,207,330,5295,6609,8737,1432,637,6714,329,8772,8837,355,8517,5601,3551,5290,356,5600,5981,6850	PDPK1,FAIM2,MAP2K7,AKT1,BIRC3,PIK3R1,SMPD1,RIPK1,MAPK14,BID,SRC,BIRC2,FADD,CFLAR,FAS,IKBKG,MAPK9,IKBKB,PIK3CA,FASLG,MAPK11,RFC1,SYK
cxcr4_pathway	CXCR4-mediated signaling events	0.0935382400414061	-2.36938494189875	76	46	0.0391156462585034	1176	2242	4318,920,54434,2475,3655,79109,2782,2870,4067,6714,5996,5331,3123,640,7409,3675,5899,919,5781,5290,3717,3672,6774,5330,1072,64223,5170,5058,5829,207,5777,5295,9525,5747,10399,9564,5788,9146,2268,2534,3984,5590,3688,2185,6776,27183	MMP9,CD4,SSH1,MTOR,ITGA6,MAPKAP1,GNB1,GRK6,LYN,SRC,RGS1,PLCB3,HLA-DRB1,BLK,VAV1,ITGA3,RALB,CD247,PTPN11,PIK3CA,JAK2,ITGA1,STAT3,PLCB2,CFL1,MLST8,PDPK1,PAK1,PXN,AKT1,PTPN6,PIK3R1,VPS4B,PTK2,GNB2L1,BCAR1,PTPRC,HGS,FGR,FYN,LIMK1,PRKCZ,ITGB1,PTK2B,STAT5A,VPS4A
cmyb_pathway	C-MYB transcription factor network	0.0983048639318959	-2.31968177256589	78	47	0.0399659863945578	1176	2242	920,1314,839,5897,51701,5250,2625,136,161882,27044,1026,891,25942,7329,2113,4353,100,6497,3950,595,4173,4609,8379,5292,6885,3815,4094,6688,5079,1052,6667,3280,6595,330,3312,10155,290,1051,10401,5743,2114,28996,4654,4254,1211,947,1436	CD4,COPA,CASP6,RAG2,NLK,SLC25A3,GATA3,ADORA2B,ZFPM1,SND1,CDKN1A,CCNB1,SIN3A,UBE2I,ETS1,MPO,ADA,SKI,LECT2,CCND1,MCM4,MYC,MAD1L1,PIM1,MAP3K7,KIT,MAF,SPI1,PAX5,CEBPD,SP1,HES1,SMARCA2,BIRC3,HSPA8,TRIM28,ANPEP,CEBPB,PIAS3,PTGS2,ETS2,HIPK2,MYOD1,KITLG,CLTA,CD34,CSF1R
vegfr1_pathway	VEGFR1 specific signals	0.108591729612771	-2.22016002896075	29	19	0.016156462585034	1176	2242	5170,207,4690,5295,857,867,5578,7422,5566,8828,25759,5228,5335,3091,2321,5290,5781,3320,8829	PDPK1,AKT1,NCK1,PIK3R1,CAV1,CBL,PRKCA,VEGFA,PRKACA,NRP2,SHC2,PGF,PLCG1,HIF1A,FLT1,PIK3CA,PTPN11,HSP90AA1,NRP1
mapktrkpathway	Trk receptor signaling mediated by the MAPK pathway	0.108591729612771	-2.22016002896075	29	19	0.016156462585034	1176	2242	5607,1958,5894,6195,6016,2353,9252,1432,5606,8851,1020,9261,5580,6722,1385,30844,7442,23623,4208	MAP2K5,EGR1,RAF1,RPS6KA1,RIT1,FOS,RPS6KA5,MAPK14,MAP2K3,CDK5R1,CDK5,MAPKAPK2,PRKCD,SRF,CREB1,EHD4,TRPV1,RUSC1,MEF2C
fcer1pathway	Fc-epsilon receptor I signaling in mast cells	0.114219746286525	-2.16963108701802	59	36	0.0306122448979592	1176	2242	5321,2207,5894,8877,5338,3937,4067,3725,7409,8611,6464,4790,3551,5781,5290,2205,6850,1843,27040,2241,2213,5829,207,5609,5783,5295,868,7456,4773,867,2353,5605,5335,8517,2534,3265	PLA2G4A,FCER1G,RAF1,SPHK1,PLD2,LCP2,LYN,JUN,VAV1,PPAP2A,SHC1,NFKB1,IKBKB,PTPN11,PIK3CA,FCER1A,SYK,DUSP1,LAT,FER,FCGR2B,PXN,AKT1,MAP2K7,PTPN13,PIK3R1,CBLB,WIPF1,NFATC2,CBL,FOS,MAP2K2,PLCG1,IKBKG,FYN,HRAS
ptp1bpathway	Signaling events mediated by PTP1B	0.11731807581797	-2.14286643614982	52	32	0.0272108843537415	1176	2242	2241,27040,207,54741,5295,857,9564,4067,6714,7297,3630,1956,9021,640,2268,5770,2534,3643,6464,1435,5618,5290,2212,6776,3717,3952,4904,6774,1000,10253,5159,1436	FER,LAT,AKT1,LEPROT,PIK3R1,CAV1,BCAR1,LYN,SRC,TYK2,INS,EGFR,SOCS3,BLK,FGR,PTPN1,FYN,INSR,SHC1,CSF1,PRLR,PIK3CA,FCGR2A,STAT5A,JAK2,LEP,YBX1,STAT3,CDH2,SPRY2,PDGFRB,CSF1R
erbb_network_pathway	ErbB receptor signaling network	0.122820021286185	-2.09703523676886	14	10	0.00850340136054422	1176	2242	685,10718,1839,374,7039,9542,2064,2065,3320,1956	BTC,NRG3,HBEGF,AREG,TGFA,NRG2,ERBB2,ERBB3,HSP90AA1,EGFR
fgf_pathway	FGF signaling pathway	0.127810640132896	-2.05720548437836	47	29	0.0246598639455782	1176	2242	5170,4318,2264,860,207,54434,5329,632,6195,5295,867,2353,6714,10298,2260,2246,3725,5335,6464,999,5781,5290,2185,3082,2017,4233,1000,10253,815	PDPK1,MMP9,FGFR4,RUNX2,AKT1,SSH1,PLAUR,BGLAP,RPS6KA1,PIK3R1,CBL,FOS,SRC,PAK4,FGFR1,FGF1,JUN,PLCG1,SHC1,CDH1,PTPN11,PIK3CA,PTK2B,HGF,CTTN,MET,CDH2,SPRY2,CAMK2A
ephbfwdpathway	EPHB forward signaling	0.130991502266252	-2.03262282608157	33	21	0.0178571428571429	1176	2242	5058,1948,1949,5829,6237,4690,5295,2047,8867,1947,6714,2890,2048,2886,5290,1946,6093,2050,3265,6453,2049	PAK1,EFNB2,EFNB3,PXN,RRAS,NCK1,PIK3R1,EPHB1,SYNJ1,EFNB1,SRC,GRIA1,EPHB2,GRB7,PIK3CA,EFNA5,ROCK1,EPHB4,HRAS,ITSN1,EPHB3
ecadherin_nascentaj_pathway	E-cadherin signaling in the nascent adherens junction	0.130991502266252	-2.03262282608157	33	21	0.0178571428571429	1176	2242	10163,2889,207,3728,1495,5295,7410,7082,55740,26999,6714,23396,595,27252,1499,999,8907,5290,1739,2017,7074	WASF2,RAPGEF1,AKT1,JUP,CTNNA1,PIK3R1,VAV2,TJP1,ENAH,CYFIP2,SRC,PIP5K1C,CCND1,KLHL20,CTNNB1,CDH1,AP1M1,PIK3CA,DLG1,CTTN,TIAM1
nfkappabalternativepathway	Alternative NF-kappaB pathway	0.133769468043355	-2.01163734833385	6	5	0.00425170068027211	1176	2242	5971,9020,4791,8945,4790	RELB,MAP3K14,NFKB2,BTRC,NFKB1
erbb2erbb3pathway	ErbB2/ErbB3 signaling events	0.14178260353937	-1.95346035548949	35	22	0.0187074829931973	1176	2242	207,4771,2475,5894,5295,2064,9542,2353,5566,6714,5605,3725,6464,10193,5601,5290,5781,3717,4776,2065,1145,6774	AKT1,NF2,MTOR,RAF1,PIK3R1,ERBB2,NRG2,FOS,PRKACA,SRC,MAP2K2,JUN,SHC1,RNF41,MAPK9,PIK3CA,PTPN11,JAK2,NFATC4,ERBB3,CHRNE,STAT3
alk1_2pathway	ALK1 pathway	0.144141090081349	-1.93696266685765	3	3	0.00255102040816327	1176	2242	2280,90,94	FKBP1A,ACVR1,ACVRL1
cdc42_pathway	CDC42 signaling events	0.151855902774978	-1.88482321583905	71	42	0.0357142857142857	1176	2242	2475,8874,5894,1495,10096,7410,324,55740,23265,81624,1432,6714,10298,5606,3725,999,1499,10092,5601,5290,1739,128239,1386,7074,1072,5058,5923,10188,5609,5295,8476,867,9564,10458,3984,5590,396,2932,388585,6198,5337,3265	MTOR,ARHGEF7,RAF1,CTNNA1,ACTR3,VAV2,APC,ENAH,EXOC7,DIAPH3,MAPK14,SRC,PAK4,MAP2K3,JUN,CDH1,CTNNB1,ARPC5,MAPK9,PIK3CA,DLG1,IQGAP3,ATF2,TIAM1,CFL1,PAK1,RASGRF1,TNK2,MAP2K7,PIK3R1,CDC42BPA,CBL,BCAR1,BAIAP2,LIMK1,PRKCZ,ARHGDIA,GSK3B,HES5,RPS6KB1,PLD1,HRAS
myc_represspathway	Validated targets of C-MYC transcriptional repression	0.152368040339748	-1.88145636677838	62	37	0.0314625850340136	1176	2242	1788,4149,7249,6908,10397,3655,3398,2064,677,10608,1026,81855,8837,595,9414,4609,6422,1385,6688,5159,1052,6667,7709,8841,3956,672,22943,6278,4800,1647,5933,3688,3394,1191,3691,4089,1649	DNMT3A,MAX,TSC2,TBP,NDRG1,ITGA6,ID2,ERBB2,ZFP36L1,MXD4,CDKN1A,SFXN3,CFLAR,CCND1,TJP2,MYC,SFRP1,CREB1,SPI1,PDGFRB,CEBPD,SP1,ZBTB17,HDAC3,LGALS1,BRCA1,DKK1,S100A7,NFYA,GADD45A,RBL1,ITGB1,IRF8,CLU,ITGB4,SMAD4,DDIT3
avb3_integrin_pathway	Integrins in angiogenesis	0.157261593074919	-1.84984466227219	46	28	0.0238095238095238	1176	2242	10451,5829,207,2335,7094,5295,4240,50848,867,7422,9564,7048,6382,6714,5286,5298,25960,7448,1435,5781,5290,2185,6198,3685,3320,6093,7414,1436	VAV3,PXN,AKT1,FN1,TLN1,PIK3R1,MFGE8,F11R,CBL,VEGFA,BCAR1,TGFBR2,SDC1,SRC,PIK3C2A,PI4KB,GPR124,VTN,CSF1,PTPN11,PIK3CA,PTK2B,RPS6KB1,ITGAV,HSP90AA1,ROCK1,VCL,CSF1R
pi3kplctrkpathway	Trk receptor signaling mediated by PI3K and PLC-gamma	0.166639966105856	-1.79191968542685	32	20	0.0170068027210884	1176	2242	5170,207,1958,2036,5295,10971,7531,6714,595,5335,6464,5580,5290,2932,6776,7534,7442,1385,2810,815	PDPK1,AKT1,EGR1,EPB41L1,PIK3R1,YWHAQ,YWHAE,SRC,CCND1,PLCG1,SHC1,PRKCD,PIK3CA,GSK3B,STAT5A,YWHAZ,TRPV1,CREB1,SFN,CAMK2A
nectin_pathway	Nectin adhesion pathway	0.168395743832677	-1.78143845164606	25	16	0.0136054421768707	1176	2242	2889,999,1499,7094,1495,5797,5295,7410,5818,5290,50848,3685,6714,5159,9855,23396	RAPGEF1,CDH1,CTNNB1,TLN1,CTNNA1,PTPRM,PIK3R1,VAV2,PVRL1,PIK3CA,F11R,ITGAV,SRC,PDGFRB,FARP2,PIP5K1C
rhoa_pathway	RhoA signaling pathway	0.172456910074708	-1.75760787038347	41	25	0.0212585034013605	1176	2242	4659,7094,57591,5338,5585,8394,2353,1729,5606,23396,3725,3491,3984,58,6550,5590,6548,6722,5962,6093,4478,7414,1386,1072,6300	PPP1R12A,TLN1,MKL1,PLD2,PKN1,PIP5K1A,FOS,DIAPH1,MAP2K3,PIP5K1C,JUN,CYR61,LIMK1,ACTA1,SLC9A3,PRKCZ,SLC9A1,SRF,RDX,ROCK1,MSN,VCL,ATF2,CFL1,MAPK12
pi3kcipathway	Class I PI3K signaling events	0.172456910074708	-1.75760787038347	41	25	0.0212585034013605	1176	2242	5170,9267,3636,64411,8874,5295,57580,375,59338,4067,6714,640,7409,5335,2268,11033,2534,5336,27071,5290,6446,3320,9266,59339,7074	PDPK1,CYTH1,INPPL1,ARAP3,ARHGEF7,PIK3R1,PREX1,ARF1,PLEKHA1,LYN,SRC,BLK,VAV1,PLCG1,FGR,ADAP1,FYN,PLCG2,DAPP1,PIK3CA,SGK1,HSP90AA1,CYTH2,PLEKHA2,TIAM1
il6_7pathway	IL6-mediated signaling events	0.182124278934424	-1.70306597365416	43	26	0.022108843537415	1176	2242	207,5295,4170,3570,2353,1432,7297,9021,1051,7409,10401,3725,8554,8543,3572,4609,4286,5580,3726,5781,5290,3717,5600,6774,1052,3659	AKT1,PIK3R1,MCL1,IL6R,FOS,MAPK14,TYK2,SOCS3,CEBPB,VAV1,PIAS3,JUN,PIAS1,LMO4,IL6ST,MYC,MITF,PRKCD,JUNB,PTPN11,PIK3CA,JAK2,MAPK11,STAT3,CEBPD,IRF1
kitpathway	Signaling events mediated by Stem cell factor receptor (c-Kit)	0.182671718050265	-1.70006462752474	52	31	0.0263605442176871	1176	2242	5170,2241,200734,207,2057,5777,5894,5295,867,4067,5605,10019,7409,1399,8651,6464,10603,4286,5781,5290,2932,4254,6776,3717,2887,6198,5287,6774,3815,3265,6591	PDPK1,FER,SPRED2,AKT1,EPOR,PTPN6,RAF1,PIK3R1,CBL,LYN,MAP2K2,SH2B3,VAV1,CRKL,SOCS1,SHC1,SH2B2,MITF,PTPN11,PIK3CA,GSK3B,KITLG,STAT5A,JAK2,GRB10,RPS6KB1,PIK3C2B,STAT3,KIT,HRAS,SNAI2
p38alphabetapathway	Regulation of p38-alpha and p38-beta	0.18270583039242	-1.69987790372412	27	17	0.0144557823129252	1176	2242	4215,5058,7189,1850,83605,8737,1432,4067,6714,5606,640,2534,2268,80824,11221,5600,1843	MAP3K3,PAK1,TRAF6,DUSP8,CCM2,RIPK1,MAPK14,LYN,SRC,MAP2K3,BLK,FYN,FGR,DUSP16,DUSP10,MAPK11,DUSP1
tcptp_pathway	Signaling events mediated by TCPTP	0.189621605429422	-1.6627247429665	36	22	0.0187074829931973	1176	2242	5295,7422,6714,3630,1956,8554,3643,5770,1435,6778,5867,5290,3688,6776,545,3082,3672,4233,6774,3837,5159,1436	PIK3R1,VEGFA,SRC,INS,EGFR,PIAS1,INSR,PTPN1,CSF1,STAT6,RAB4A,PIK3CA,ITGB1,STAT5A,ATR,HGF,ITGA1,MET,STAT3,KPNB1,PDGFRB,CSF1R
fak_pathway	Signaling events mediated by focal adhesion kinase	0.190783581043521	-1.65661557690176	54	32	0.0272108843537415	1176	2242	5058,23092,5829,64283,2889,6237,9826,1793,7094,8874,5894,5295,23162,87,9564,2113,6714,6455,824,595,3725,5335,2534,50807,58,5601,2886,4323,5290,3688,3685,7414	PAK1,ARHGAP26,PXN,ARHGEF28,RAPGEF1,RRAS,ARHGEF11,DOCK1,TLN1,ARHGEF7,RAF1,PIK3R1,MAPK8IP3,ACTN1,BCAR1,ETS1,SRC,SH3GL1,CAPN2,CCND1,JUN,PLCG1,FYN,ASAP1,ACTA1,MAPK9,GRB7,MMP14,PIK3CA,ITGB1,ITGAV,VCL
p38_mkk3_6pathway	p38 MAPK signaling pathway	0.196288843260692	-1.62816801446165	29	18	0.0153061224489796	1176	2242	4215,7189,9344,7186,83605,1432,9064,5606,1647,23118,816,4616,472,5600,4217,6885,4294,51347	MAP3K3,TRAF6,TAOK2,TRAF2,CCM2,MAPK14,MAP3K6,MAP2K3,GADD45A,TAB2,CAMK2B,GADD45B,ATM,MAPK11,MAP3K5,MAP3K7,MAP3K10,TAOK3
rb_1pathway	Regulation of retinoblastoma protein	0.198721381359994	-1.61585152897297	56	33	0.0280612244897959	1176	2242	860,6908,5894,11016,5948,6597,1026,7042,6441,1432,898,6598,25,3725,145258,5601,4286,5600,4233,6688,1386,1052,28227,632,8841,1437,5515,1051,6046,7027,4654,1487,4208	RUNX2,TBP,RAF1,ATF7,RBP2,SMARCA4,CDKN1A,TGFB2,SFTPD,MAPK14,CCNE1,SMARCB1,ABL1,JUN,GSC,MAPK9,MITF,MAPK11,MET,SPI1,ATF2,CEBPD,PPP2R3B,BGLAP,HDAC3,CSF2,PPP2CA,CEBPB,BRD2,TFDP1,MYOD1,CTBP1,MEF2C
lpa4_pathway	LPA4-mediated signaling events	0.199455421647672	-1.61216451800859	15	10	0.00850340136054422	1176	2242	111,114,2774,107,109,112,1385,5566,9252,113	ADCY5,ADCY8,GNAL,ADCY1,ADCY3,ADCY6,CREB1,PRKACA,RPS6KA5,ADCY7
pdgfrapathway	PDGFR-alpha signaling pathway	0.20078116645119	-1.60553968813712	22	14	0.0119047619047619	1176	2242	1399,3725,6461,5335,2889,6464,5295,5290,6722,90525,3685,857,859,2353	CRKL,JUN,SHB,PLCG1,RAPGEF1,SHC1,PIK3R1,PIK3CA,SRF,SHF,ITGAV,CAV1,CAV3,FOS
epha_fwdpathway	EPHA forward signaling	0.20919782321941	-1.56447495210645	31	19	0.016156462585034	1176	2242	2042,10451,285220,7410,1944,867,4067,6714,1020,1399,640,5335,2268,2534,1969,1946,1942,6093,2046	EPHA3,VAV3,EPHA6,VAV2,EFNA3,CBL,LYN,SRC,CDK5,CRKL,BLK,PLCG1,FGR,FYN,EPHA2,EFNA5,EFNA1,ROCK1,EPHA8
lkb1_pathway	LKB1 signaling events	0.221049972340519	-1.50936648383761	42	25	0.0212585034013605	1176	2242	23235,7249,2475,92335,10971,55437,7531,5566,2011,200186,57521,114790,4133,4609,5664,2932,7534,3320,1385,150094,1509,9024,4089,2810,64223	SIK2,TSC2,MTOR,STRADA,YWHAQ,STRADB,YWHAE,PRKACA,MARK2,CRTC2,RPTOR,STK11IP,MAP2,MYC,PSEN2,GSK3B,YWHAZ,HSP90AA1,CREB1,SIK1,CTSD,BRSK2,SMAD4,SFN,MLST8
endothelinpathway	Endothelins	0.226613835943669	-1.4845078733658	53	31	0.0263605442176871	1176	2242	5321,5058,207,1908,5894,1906,107,57105,5578,2353,9564,1432,6714,5605,5331,5583,3725,2768,1907,111,114,5580,6550,6548,2185,109,112,3717,5330,3265,113	PLA2G4A,PAK1,AKT1,EDN3,RAF1,EDN1,ADCY1,CYSLTR2,PRKCA,FOS,BCAR1,MAPK14,SRC,MAP2K2,PLCB3,PRKCH,JUN,GNA12,EDN2,ADCY5,ADCY8,PRKCD,SLC9A3,SLC9A1,PTK2B,ADCY3,ADCY6,JAK2,PLCB2,HRAS,ADCY7
tnfpathway	TNF receptor signaling pathway	0.230796638687784	-1.46621830819868	44	26	0.022108843537415	1176	2242	4215,5871,6868,1540,5609,7128,330,7186,6609,8737,10399,857,8439,329,8772,5606,8517,7185,11183,8878,4790,3551,5590,7132,6885,4217	MAP3K3,MAP4K2,ADAM17,CYLD,MAP2K7,TNFAIP3,BIRC3,TRAF2,SMPD1,RIPK1,GNB2L1,CAV1,NSMAF,BIRC2,FADD,MAP2K3,IKBKG,TRAF1,MAP4K5,SQSTM1,NFKB1,IKBKB,PRKCZ,TNFRSF1A,MAP3K7,MAP3K5
glypican_1pathway	Glypican 1 network	0.231818047465367	-1.46180249318936	26	16	0.0136054421768707	1176	2242	7046,7422,284217,7048,4067,6714,351,2260,640,4087,2534,2268,2321,3084,462,2817	TGFBR1,VEGFA,LAMA1,TGFBR2,LYN,SRC,APP,FGFR1,BLK,SMAD2,FYN,FGR,FLT1,NRG1,SERPINC1,GPC1
hivnefpathway	HIV-1 Nef: Negative effector of Fas and TNF-alpha	0.233194445245786	-1.45588264449024	35	21	0.0178571428571429	1176	2242	1677,5609,330,839,7186,8737,54205,637,8772,8837,355,7185,1616,919,4790,4792,7132,356,317,9020,4217	DFFB,MAP2K7,BIRC3,CASP6,TRAF2,RIPK1,CYCS,BID,FADD,CFLAR,FAS,TRAF1,DAXX,CD247,NFKB1,NFKBIA,TNFRSF1A,FASLG,APAF1,MAP3K14,MAP3K5
ps1pathway	Presenilin action in Notch and Wnt signaling	0.240211535563408	-1.42623534566256	46	27	0.0229591836734694	1176	2242	4851,23291,79412,51107,51701,166,324,2353,1452,22943,3725,595,28514,1499,4609,8312,1840,85407,7088,2932,3516,1855,6885,1487,5528,8945,8321	NOTCH1,FBXW11,KREMEN2,APH1A,NLK,AES,APC,FOS,CSNK1A1,DKK1,JUN,CCND1,DLL1,CTNNB1,MYC,AXIN1,DTX1,NKD1,TLE1,GSK3B,RBPJ,DVL1,MAP3K7,CTBP1,PPP2R5D,BTRC,FZD1
a4b1_paxdep_pathway	Paxillin-dependent events mediated by a4b1	0.240732129826358	-1.42407045815603	19	12	0.0102040816326531	1176	2242	1399,3689,5829,1793,7094,5295,3688,5290,28964,867,9564,5566	CRKL,ITGB2,PXN,DOCK1,TLN1,PIK3R1,ITGB1,PIK3CA,GIT1,CBL,BCAR1,PRKACA
ecadherin_keratinocyte_pathway	E-cadherin signaling in keratinocytes	0.240732129826358	-1.42407045815603	19	12	0.0102040816326531	1176	2242	5335,7791,2534,207,999,1495,5295,5290,8394,846,6714,1956	PLCG1,ZYX,FYN,AKT1,CDH1,CTNNA1,PIK3R1,PIK3CA,PIP5K1A,CASR,SRC,EGFR
tcrcalciumpathway	Calcium signaling in the CD4+ TCR pathway	0.245837151498152	-1.40308594803898	28	17	0.0144557823129252	1176	2242	3562,3565,5451,4773,1437,2353,4772,5566,55509,3725,2280,5743,4775,3726,356,23523,8061	IL3,IL4,POU2F1,NFATC2,CSF2,FOS,NFATC1,PRKACA,BATF3,JUN,FKBP1A,PTGS2,NFATC3,JUNB,FASLG,CABIN1,FOSL1
nfat_tfpathway	Calcineurin-regulated NFAT-dependent transcription in lymphocytes	0.249313104605205	-1.38904572422964	48	28	0.0238095238095238	1176	2242	3562,1958,1019,3565,1606,868,5451,2625,4773,1960,1437,2353,4772,1959,55509,3725,3662,5743,5770,4775,3726,3576,356,30009,8061,4094,3567,5796	IL3,EGR1,CDK4,IL4,DGKA,CBLB,POU2F1,GATA3,NFATC2,EGR3,CSF2,FOS,NFATC1,EGR2,BATF3,JUN,IRF4,PTGS2,PTPN1,NFATC3,JUNB,IL8,FASLG,TBX21,FOSL1,MAF,IL5,PTPRK
nfkappabatypicalpathway	Atypical NF-kappaB pathway	0.269129937313622	-1.31256097766516	14	9	0.0076530612244898	1176	2242	5295,3551,4792,4790,5290,1432,6714,6850,8945	PIK3R1,IKBKB,NFKBIA,NFKB1,PIK3CA,MAPK14,SRC,SYK,BTRC
ecadherin_1_pathway	E-cadherin signaling events	0.27502218209731	-1.29090352239655	2	2	0.00170068027210884	1176	2242	999,1499	CDH1,CTNNB1
hdac_classii_pathway	Signaling events mediated by HDAC Class II	0.283107208641948	-1.26192962395304	34	20	0.0170068027210884	1176	2242	9612,7280,2908,79885,8841,2782,5905,54880,83933,10013,7531,7329,9734,10376,7514,9759,51564,6722,3320,4208	NCOR2,TUBB2A,NR3C1,HDAC11,HDAC3,GNB1,RANGAP1,BCOR,HDAC10,HDAC6,YWHAE,UBE2I,HDAC9,TUBA1B,XPO1,HDAC4,HDAC7,SRF,HSP90AA1,MEF2C
fra_pathway	Validated transcriptional targets of AP1 family members Fra1 and Fra2	0.283107208641948	-1.26192962395304	34	20	0.0170068027210884	1176	2242	4318,3976,55787,5329,632,4773,3162,4772,3713,3725,595,3909,4775,3726,3576,4313,3691,8061,9988,6667	MMP9,LIF,TXLNG,PLAUR,BGLAP,NFATC2,HMOX1,NFATC1,IVL,JUN,CCND1,LAMA3,NFATC3,JUNB,IL8,MMP2,ITGB4,FOSL1,DMTF1,SP1
arf6_pathway	Arf6 signaling events	0.283107208641948	-1.26192962395304	34	20	0.0170068027210884	1176	2242	5829,116984,4690,2769,28964,154,3973,6714,2767,9630,1956,23527,11033,1969,9922,3082,26034,1942,9266,4233	PXN,ARAP2,NCK1,GNA15,GIT1,ADRB2,LHCGR,SRC,GNA11,GNA14,EGFR,ACAP2,ADAP1,EPHA2,IQSEC1,HGF,IPCEF1,EFNA1,CYTH2,MET
erbb1_internalization_pathway	Internalization of ErbB1	0.283107208641948	-1.26192962395304	34	20	0.0170068027210884	1176	2242	7323,8874,5894,5295,868,29924,5868,51652,867,8867,6714,1956,30011,9146,57732,7322,5290,7251,10253,6453	UBE2D3,ARHGEF7,RAF1,PIK3R1,CBLB,EPN1,RAB5A,CHMP3,CBL,SYNJ1,SRC,EGFR,SH3KBP1,HGS,ZFYVE28,UBE2D2,PIK3CA,TSG101,SPRY2,ITSN1
pi3kciaktpathway	Class I PI3K signaling events mediated by Akt	0.283107208641948	-1.26192962395304	34	20	0.0170068027210884	1176	2242	5170,207,2931,2475,5591,5894,79109,10971,1026,7531,5566,6714,10000,2932,7534,3320,4217,9882,2810,64223	PDPK1,AKT1,GSK3A,MTOR,PRKDC,RAF1,MAPKAP1,YWHAQ,CDKN1A,YWHAE,PRKACA,SRC,AKT3,GSK3B,YWHAZ,HSP90AA1,MAP3K5,TBC1D4,SFN,MLST8
reg_gr_pathway	Glucocorticoid receptor regulatory network	0.28806308922737	-1.24457576301903	82	46	0.0391156462585034	1176	2242	7433,1958,6908,3596,3565,5087,6597,2625,1026,5566,1432,3383,1020,3725,51111,4790,5601,6446,30009,5600,3320,1385,6688,10499,5567,3852,207,2908,3164,632,5451,1437,2353,4772,8851,3576,2932,7251,9970,6776,2289,5536,3567,3066,2810,3659	VIPR1,EGR1,TBP,IL13,IL4,PBX1,SMARCA4,GATA3,CDKN1A,PRKACA,MAPK14,ICAM1,CDK5,JUN,SUV420H1,NFKB1,MAPK9,SGK1,TBX21,MAPK11,HSP90AA1,CREB1,SPI1,NCOA2,PRKACB,KRT5,AKT1,NR3C1,NR4A1,BGLAP,POU2F1,CSF2,FOS,NFATC1,CDK5R1,IL8,GSK3B,TSG101,NR1I3,STAT5A,FKBP5,PPP5C,IL5,HDAC2,SFN,IRF1
retinoic_acid_pathway	Retinoic acid receptors-mediated signaling	0.289504483844198	-1.23958449385346	25	15	0.0127551020408163	1176	2242	7421,6258,9612,5914,207,902,8850,8841,6256,5578,1432,8204,5566,983,10499	VDR,RXRG,NCOR2,RARA,AKT1,CCNH,KAT2B,HDAC3,RXRA,PRKCA,MAPK14,NRIP1,PRKACA,CDK1,NCOA2
notch_pathway	Notch signaling pathway	0.290694445825642	-1.23548257780677	58	33	0.0280612244897959	1176	2242	9612,54567,3565,84708,2625,3714,1026,4853,92737,8766,595,182,28514,4609,55294,4237,9794,2023,8788,4851,51107,5045,8038,867,2011,9148,1840,6500,3516,7528,1487,8945,8650	NCOR2,DLL4,IL4,LNX1,GATA3,JAG2,CDKN1A,NOTCH2,DNER,RAB11A,CCND1,JAG1,DLL1,MYC,FBXW7,MFAP2,MAML1,ENO1,DLK1,NOTCH1,APH1A,FURIN,ADAM12,CBL,MARK2,NEURL1,DTX1,SKP1,RBPJ,YY1,CTBP1,BTRC,NUMB
ephrinbrevpathway	Ephrin B reverse signaling	0.303253999571548	-1.19318454222089	27	16	0.0136054421768707	1176	2242	1948,5783,5295,2047,4067,1947,6714,640,2534,2268,2048,5998,5290,2050,6885,7074	EFNB2,PTPN13,PIK3R1,EPHB1,LYN,EFNB1,SRC,BLK,FYN,FGR,EPHB2,RGS3,PIK3CA,EPHB4,MAP3K7,TIAM1
il12_2pathway	IL12-mediated signaling events	0.305585450641629	-1.1855258319801	62	35	0.0297619047619048	1176	2242	920,2475,3565,567,3606,1432,3105,5606,3123,8651,8320,3142,919,6351,4790,30009,5971,3717,4791,6774,1386,7879,6775,3560,2353,7297,3554,925,6778,4616,356,6776,56848,4843,1234	CD4,MTOR,IL4,B2M,IL18,MAPK14,HLA-A,MAP2K3,HLA-DRB1,SOCS1,EOMES,HLX,CD247,CCL4,NFKB1,TBX21,RELB,JAK2,NFKB2,STAT3,ATF2,RAB7A,STAT4,IL2RB,FOS,TYK2,IL1R1,CD8A,STAT6,GADD45B,FASLG,STAT5A,SPHK2,NOS2,CCR5
reelinpathway	Reelin signaling pathway	0.316030588168416	-1.15191627207853	29	17	0.0144557823129252	1176	2242	4043,2889,5609,207,5295,867,9479,8851,1020,1399,2534,3675,5290,3688,2932,9181,7804	LRPAP1,RAPGEF1,MAP2K7,AKT1,PIK3R1,CBL,MAPK8IP1,CDK5R1,CDK5,CRKL,FYN,ITGA3,PIK3CA,ITGB1,GSK3B,ARHGEF2,LRP8
bard1pathway	BARD1 signaling events	0.316030588168416	-1.15191627207853	29	17	0.0144557823129252	1176	2242	7323,2176,5591,4869,672,2189,2178,580,2175,2188,898,7520,5111,10111,472,545,1477	UBE2D3,FANCC,PRKDC,NPM1,BRCA1,FANCG,FANCE,BARD1,FANCA,FANCF,CCNE1,XRCC5,PCNA,RAD50,ATM,ATR,CSTF1
telomerasepathway	Regulation of Telomerase	0.31967010681812	-1.14046573114134	66	37	0.0314625850340136	1176	2242	54984,4149,2475,641,25942,7531,8658,4084,25,595,54386,3725,7337,23381,4609,26277,4790,3320,6667,207,3183,4691,1736,2353,3364,1956,7520,4088,7015,10111,472,6198,7026,7013,25913,3066,3659	PINX1,MAX,MTOR,BLM,SIN3A,YWHAE,TNKS,MXD1,ABL1,CCND1,TERF2IP,JUN,UBE3A,SMG5,MYC,TINF2,NFKB1,HSP90AA1,SP1,AKT1,HNRNPC,NCL,DKC1,FOS,HUS1,EGFR,XRCC5,SMAD3,TERT,RAD50,ATM,RPS6KB1,NR2F2,TERF1,POT1,HDAC2,IRF1
syndecan_4_pathway	Syndecan-4-mediated signaling events	0.327957821854246	-1.11487027077443	31	18	0.0153061224489796	1176	2242	4318,2147,2335,84309,6385,87,10755,8038,5578,284217,23495,2260,4192,3909,5580,1785,3688,6386	MMP9,F2,FN1,NUDT16L1,SDC4,ACTN1,GIPC1,ADAM12,PRKCA,LAMA1,TNFRSF13B,FGFR1,MDK,LAMA3,PRKCD,DNM2,ITGB1,SDCBP
aurora_a_pathway	Aurora A signaling	0.327957821854246	-1.11487027077443	31	18	0.0153061224489796	1176	2242	5058,1058,207,6867,8874,22974,28964,672,5566,64506,1647,4792,51343,2932,994,5528,10460,54998	PAK1,CENPA,AKT1,TACC1,ARHGEF7,TPX2,GIT1,BRCA1,PRKACA,CPEB1,GADD45A,NFKBIA,FZR1,GSK3B,CDC25B,PPP2R5D,TACC3,AURKAIP1
p38gammadeltapathway	Signaling mediated by p38-gamma and p38-delta	0.331907903875644	-1.10289774651251	11	7	0.00595238095238095	1176	2242	595,5585,3925,51776,5606,6300,29904	CCND1,PKN1,STMN1,ZAK,MAP2K3,MAPK12,EEF2K
arf6_traffickingpathway	Arf6 trafficking events	0.333425010032826	-1.09833729638348	44	25	0.0212585034013605	1176	2242	274,3728,1495,3655,9341,23162,5338,10066,23265,154,6382,3630,23396,5898,8853,9043,999,1499,3675,1785,3688,55770,5337,3672,1363	BIN1,JUP,CTNNA1,ITGA6,VAMP3,MAPK8IP3,PLD2,SCAMP2,EXOC7,ADRB2,SDC1,INS,PIP5K1C,RALA,ASAP2,SPAG9,CDH1,CTNNB1,ITGA3,DNM2,ITGB1,EXOC2,PLD1,ITGA1,CPE
epopathway	EPO signaling pathway	0.339138212544983	-1.08134754806908	33	19	0.016156462585034	1176	2242	2889,2057,5777,5295,7410,867,1432,4067,9021,10019,1399,5335,6464,4790,5336,5781,6776,3717,3265	RAPGEF1,EPOR,PTPN6,PIK3R1,VAV2,CBL,MAPK14,LYN,SOCS3,SH2B3,CRKL,PLCG1,SHC1,NFKB1,PLCG2,PTPN11,STAT5A,JAK2,HRAS
ncadherinpathway	N-cadherin signaling events	0.339138212544983	-1.08134754806908	33	19	0.016156462585034	1176	2242	2241,22919,1495,5295,2260,23396,747,5335,2934,5770,221955,1499,8312,2596,5290,6093,2017,1000,818	FER,MAPRE1,CTNNA1,PIK3R1,FGFR1,PIP5K1C,DAGLA,PLCG1,GSN,PTPN1,DAGLB,CTNNB1,AXIN1,GAP43,PIK3CA,ROCK1,CTTN,CDH2,CAMK2G
myc_pathway	C-MYC pathway	0.341751160882768	-1.07367240650669	22	13	0.0110544217687075	1176	2242	5515,7709,26959,6881,4149,2648,5525,8607,5300,4609,8312,2932,86	PPP2CA,ZBTB17,HBP1,TAF10,MAX,KAT2A,PPP2R5A,RUVBL1,PIN1,MYC,AXIN1,GSK3B,ACTL6A
a4b1_paxindep_pathway	Paxillin-independent events mediated by a4b1 and a4b7	0.341751160882768	-1.07367240650669	22	13	0.0110544217687075	1176	2242	1399,5829,2057,1793,5295,3688,5290,3717,28964,867,960,9564,6714	CRKL,PXN,EPOR,DOCK1,PIK3R1,ITGB1,PIK3CA,JAK2,GIT1,CBL,CD44,BCAR1,SRC
syndecan_pathway	Proteogylcan syndecan-mediated signaling events	0.350020145945213	-1.04976456631172	4	3	0.00255102040816327	1176	2242	9672,6382,6385	SDC3,SDC1,SDC4
angiopoietinreceptor_pathway	Angiopoietin receptor Tie2-mediated signaling	0.350545007381835	-1.04826617167324	48	27	0.0229591836734694	1176	2242	5058,2147,5829,2335,207,2888,4690,5295,5338,1026,2113,1432,2534,6464,2886,4313,4790,5781,5290,3688,6776,51378,6198,1998,9046,284,2242	PAK1,F2,PXN,FN1,AKT1,GRB14,NCK1,PIK3R1,PLD2,CDKN1A,ETS1,MAPK14,FYN,SHC1,GRB7,MMP2,NFKB1,PTPN11,PIK3CA,ITGB1,STAT5A,ANGPT4,RPS6KB1,ELF2,DOK2,ANGPT1,FES
amb2_neutrophils_pathway	amb2 Integrin signaling	0.350545007381835	-1.04826617167324	48	27	0.0229591836734694	1176	2242	4318,3146,207,2335,6403,7094,5329,6404,4067,4353,4485,6714,83700,3383,640,3689,7070,2268,2534,4486,7448,4018,3491,4790,4313,5590,6093	MMP9,HMGB1,AKT1,FN1,SELP,TLN1,PLAUR,SELPLG,LYN,MPO,MST1,SRC,JAM3,ICAM1,BLK,ITGB2,THY1,FGR,FYN,MST1R,VTN,LPA,CYR61,NFKB1,MMP2,PRKCZ,ROCK1
circadianpathway	Circadian rhythm pathway	0.354569846080112	-1.03684992539294	13	8	0.00680272108843537	1176	2242	5187,1454,406,1111,545,11091,8553,9572	PER1,CSNK1E,ARNTL,CHEK1,ATR,WDR5,BHLHE40,NR1D1
hif1apathway	Hypoxic and oxygen homeostasis regulation of HIF-1-alpha	0.373641710814667	-0.984457933209825	15	9	0.0076530612244898	1176	2242	6923,3091,9978,8453,6921,3320,10399,405,10956	TCEB2,HIF1A,RBX1,CUL2,TCEB1,HSP90AA1,GNB2L1,ARNT,OS9
wnt_signaling_pathway	Wnt signaling network	0.379809797004713	-0.968084685768886	28	16	0.0136054421768707	1176	2242	115908,79412,284654,8325,7472,11211,7476,7477,83999,8323,22943,89780,7855,3487,10159,8321	CTHRC1,KREMEN2,RSPO1,FZD8,WNT2,FZD10,WNT7A,WNT7B,KREMEN1,FZD6,DKK1,WNT3A,FZD5,IGFBP4,ATP6AP2,FZD1
insulin_pathway	Insulin Pathway	0.386421727598081	-0.950825947380774	43	24	0.0204081632653061	1176	2242	5170,10580,2889,207,2888,4690,5295,23265,857,867,3630,5770,3643,6464,10603,1978,5781,5290,5590,6446,55770,6198,2887,3265	PDPK1,SORBS1,RAPGEF1,AKT1,GRB14,NCK1,PIK3R1,EXOC7,CAV1,CBL,INS,PTPN1,INSR,SHC1,SH2B2,EIF4EBP1,PTPN11,PIK3CA,PRKCZ,SGK1,EXOC2,RPS6KB1,GRB10,HRAS
hedgehog_glipathway	Hedgehog signaling events mediated by Gli proteins	0.386421727598081	-0.950825947380774	43	24	0.0204081632653061	1176	2242	1455,23291,2736,207,1454,5727,26160,2782,25942,1452,5566,8554,7514,3170,53944,5580,6469,11127,2932,8945,1456,9788,3066,1453	CSNK1G2,FBXW11,GLI2,AKT1,CSNK1E,PTCH1,IFT172,GNB1,SIN3A,CSNK1A1,PRKACA,PIAS1,XPO1,FOXA2,CSNK1G1,PRKCD,SHH,KIF3A,GSK3B,BTRC,CSNK1G3,MTSS1,HDAC2,CSNK1D
syndecan_1_pathway	Syndecan-1-mediated signaling events	0.390082963150687	-0.941395836454016	17	10	0.00850340136054422	1176	2242	4318,5479,10855,682,3082,6386,4233,6382,5566,3911	MMP9,PPIB,HPSE,BSG,HGF,SDCBP,MET,SDC1,PRKACA,LAMA5
cdc42_reg_pathway	Regulation of CDC42 activity	0.390608522238139	-0.940049442451567	30	17	0.0144557823129252	1176	2242	10451,8874,10928,7410,324,28964,50618,8412,5335,23263,396,392,57572,6453,23348,2245,9855	VAV3,ARHGEF7,RALBP1,VAV2,APC,GIT1,ITSN2,BCAR3,PLCG1,MCF2L,ARHGDIA,ARHGAP1,DOCK6,ITSN1,DOCK9,FGD1,FARP2
avb3_opn_pathway	Osteopontin-mediated events	0.400677890797587	-0.914597439309564	32	18	0.0153061224489796	1176	2242	4318,5058,10451,5295,8394,2353,9564,3725,2934,4790,4313,4792,5290,2185,3685,9020,960,6850	MMP9,PAK1,VAV3,PIK3R1,PIP5K1A,FOS,BCAR1,JUN,GSN,NFKB1,MMP2,NFKBIA,PIK3CA,PTK2B,ITGAV,MAP3K14,CD44,SYK
alphasynuclein_pathway	Alpha-synuclein signaling	0.400677890797587	-0.914597439309564	32	18	0.0153061224489796	1176	2242	5071,2869,1861,6531,5338,4067,6714,11315,2280,640,2268,2534,5580,2185,5337,5330,5528,6850	PARK2,GRK5,TOR1A,SLC6A3,PLD2,LYN,SRC,PARK7,FKBP1A,BLK,FGR,FYN,PRKCD,PTK2B,PLD1,PLCB2,PPP2R5D,SYK
myc_activpathway	Validated targets of C-MYC transcriptional activation	0.409939116963367	-0.891746625521589	81	44	0.0374149659863946	1176	2242	4318,4149,8886,6513,3398,4869,891,7037,6135,790,661,11235,5366,9112,4609,3320,5292,23089,1977,2023,993,6881,6470,2597,2648,1019,3939,1871,1973,4691,83879,4953,4088,1981,3308,8607,7015,1104,5757,3159,57678,8061,86,4089	MMP9,MAX,DDX18,SLC2A1,ID2,NPM1,CCNB1,TFRC,RPL11,CAD,POLR3D,PDCD10,PMAIP1,MTA1,MYC,HSP90AA1,PIM1,PEG10,EIF4E,ENO1,CDC25A,TAF10,SHMT1,GAPDH,KAT2A,CDK4,LDHA,E2F3,EIF4A1,NCL,CDCA7,ODC1,SMAD3,EIF4G1,HSPA4,RUVBL1,TERT,RCC1,PTMA,HMGA1,GPAM,FOSL1,ACTL6A,SMAD4
ephrina_ephapathway	EphrinA-EPHA pathway	0.417959776143843	-0.872370080408668	8	5	0.00425170068027211	1176	2242	2042,1946,285220,1969,2046	EPHA3,EFNA5,EPHA6,EPHA2,EPHA8
atf2_pathway	ATF-2 transcription factor network	0.430315387088435	-0.843236880798453	55	30	0.0255102040816327	1176	2242	3280,1850,1019,8452,5451,467,672,7042,5578,2353,1432,1847,3630,9021,3725,595,1647,3726,3576,5601,4313,9555,11221,5600,1385,1386,4843,43,1649,1843	HES1,DUSP8,CDK4,CUL3,POU2F1,ATF3,BRCA1,TGFB2,PRKCA,FOS,MAPK14,DUSP5,INS,SOCS3,JUN,CCND1,GADD45A,JUNB,IL8,MAPK9,MMP2,H2AFY,DUSP10,MAPK11,CREB1,ATF2,NOS2,ACHE,DDIT3,DUSP1
ifngpathway	IFN-gamma pathway	0.435296716608314	-0.831727373277249	40	22	0.0187074829931973	1176	2242	51588,2889,207,2475,5295,4092,867,1051,1399,8554,817,8651,816,5580,5290,10379,5781,3717,6774,818,815,3659	PIAS4,RAPGEF1,AKT1,MTOR,PIK3R1,SMAD7,CBL,CEBPB,CRKL,PIAS1,CAMK2D,SOCS1,CAMK2B,PRKCD,PIK3CA,IRF9,PTPN11,JAK2,STAT3,CAMK2G,CAMK2A,IRF1
ar_pathway	Coregulation of Androgen receptor activity	0.436684567450805	-0.828544158133138	57	31	0.0263605442176871	1176	2242	51588,3178,7050,10451,207,23598,4117,5591,2274,672,7329,5052,3817,7520,595,10401,8554,5036,2934,7337,1499,896,6840,6722,2185,57178,8204,23081,10499,10498,58190	PIAS4,HNRNPA1,TGIF1,VAV3,AKT1,PATZ1,MAK,PRKDC,FHL2,BRCA1,UBE2I,PRDX1,KLK2,XRCC5,CCND1,PIAS3,PIAS1,PA2G4,GSN,UBE3A,CTNNB1,CCND3,SVIL,SRF,PTK2B,ZMIZ1,NRIP1,KDM4C,NCOA2,CARM1,CTDSP1
il4_2pathway	IL4-mediated signaling events	0.454540247518921	-0.788468815888258	63	34	0.0289115646258503	1176	2242	7033,6403,2475,3565,6361,5284,2113,1432,3662,8651,6464,5290,3717,3566,6688,4603,2242,6667,207,5777,1277,5295,3586,867,1959,9021,1051,7070,6778,6198,6776,3159,9046,3567	TFF3,SELP,MTOR,IL4,CCL17,PIGR,ETS1,MAPK14,IRF4,SOCS1,SHC1,PIK3CA,JAK2,IL4R,SPI1,MYBL1,FES,SP1,AKT1,PTPN6,COL1A1,PIK3R1,IL10,CBL,EGR2,SOCS3,CEBPB,THY1,STAT6,RPS6KB1,STAT5A,HMGA1,DOK2,IL5
erbb1_downstream_pathway	ErbB1 downstream signaling	0.46254304220061	-0.771015662142327	103	55	0.0467687074829932	1176	2242	10163,5607,1958,2475,5894,10096,7410,79109,5900,5338,9712,81624,7531,5578,9252,6714,824,3725,1124,55845,5518,10092,4609,5580,5601,5290,6548,8986,1385,6774,1386,9610,1843,64223,5170,207,9047,5295,10971,5868,26999,2353,5605,378,10458,1956,5515,5898,5590,6722,7534,5337,5536,2810,4208	WASF2,MAP2K5,EGR1,MTOR,RAF1,ACTR3,VAV2,MAPKAP1,RALGDS,PLD2,USP6NL,DIAPH3,YWHAE,PRKCA,RPS6KA5,SRC,CAPN2,JUN,CHN2,BRK1,PPP2R1A,ARPC5,MYC,PRKCD,MAPK9,PIK3CA,SLC9A1,RPS6KA4,CREB1,STAT3,ATF2,RIN1,DUSP1,MLST8,PDPK1,AKT1,SH2D2A,PIK3R1,YWHAQ,RAB5A,CYFIP2,FOS,MAP2K2,ARF4,BAIAP2,EGFR,PPP2CA,RALA,PRKCZ,SRF,YWHAZ,PLD1,PPP5C,SFN,MEF2C
rxr_vdr_pathway	RXR and RAR heterodimerization with other nuclear receptor	0.468489724434998	-0.758241110447076	14	8	0.00680272108843537	1176	2242	84498,7421,6258,9612,3164,9971,6256,6198	FAM120B,VDR,RXRG,NCOR2,NR4A1,NR1H4,RXRA,RPS6KB1
ar_nongenomic_pathway	Nongenotropic Androgen signaling	0.490565856818524	-0.712195744323717	18	10	0.00850340136054422	1176	2242	207,5894,5295,5290,2782,1385,2353,5605,6714,3265	AKT1,RAF1,PIK3R1,PIK3CA,GNB1,CREB1,FOS,MAP2K2,SRC,HRAS
foxm1pathway	FOXM1 transcription factor network	0.495458987741836	-0.702270698078973	39	21	0.0178571428571429	1176	2242	1058,2931,1019,7039,1063,2119,891,2353,983,3303,2619,3304,595,3175,4775,4609,4313,4751,1163,994,6667	CENPA,GSK3A,CDK4,TGFA,CENPF,ETV5,CCNB1,FOS,CDK1,HSPA1A,GAS1,HSPA1B,CCND1,ONECUT1,NFATC3,MYC,MMP2,NEK2,CKS1B,CDC25B,SP1
hedgehog_2pathway	Signaling events mediated by the Hedgehog family	0.508165997092635	-0.67694711884963	22	12	0.0102040816326531	1176	2242	4043,2736,207,5295,55733,6469,5290,5727,7042,50937,6491,2619	LRPAP1,GLI2,AKT1,PIK3R1,HHAT,SHH,PIK3CA,PTCH1,TGFB2,CDON,STIL,GAS1
txa2pathway	Thromboxane A2 receptor signaling	0.513429225807607	-0.666643086166865	45	24	0.0204081632653061	1176	2242	207,5739,2782,5578,4067,1432,5566,6714,8766,3383,1956,640,5583,2268,2534,5580,9138,5590,5600,6093,7052,2771,5330,6850	AKT1,PTGIR,GNB1,PRKCA,LYN,MAPK14,PRKACA,SRC,RAB11A,ICAM1,EGFR,BLK,PRKCH,FGR,FYN,PRKCD,ARHGEF1,PRKCZ,MAPK11,ROCK1,TGM2,GNAI2,PLCB2,SYK
foxopathway	FoxO family signaling	0.51890752740622	-0.65602958624571	47	25	0.0212585034013605	1176	2242	7874,1455,207,8850,1454,10971,7531,891,1452,7763,4485,847,7514,114907,1647,1499,53944,5601,3551,356,6446,7534,1453,1456,2810	USP7,CSNK1G2,AKT1,KAT2B,CSNK1E,YWHAQ,YWHAE,CCNB1,CSNK1A1,ZFAND5,MST1,CAT,XPO1,FBXO32,GADD45A,CTNNB1,CSNK1G1,MAPK9,IKBKB,FASLG,SGK1,YWHAZ,CSNK1D,CSNK1G3,SFN
er_nongenomic_pathway	Plasma membrane estrogen receptor signaling	0.522910701450253	-0.648344572420394	26	14	0.0119047619047619	1176	2242	4318,6801,1839,207,5295,4313,5290,2782,5600,9564,5330,4478,6714,5331	MMP9,STRN,HBEGF,AKT1,PIK3R1,MMP2,PIK3CA,GNB1,MAPK11,BCAR1,PLCB2,MSN,SRC,PLCB3
cd8tcrpathway	TCR signaling in naive CD8+ T cells	0.524168214298997	-0.645942626522305	49	26	0.022108843537415	1176	2242	5170,7189,27040,207,942,5777,1326,10892,83593,567,867,3937,5578,3105,5788,7409,925,8517,5335,2534,919,3551,84876,9020,5551,940	PDPK1,TRAF6,LAT,AKT1,CD86,PTPN6,MAP3K8,MALT1,RASSF5,B2M,CBL,LCP2,PRKCA,HLA-A,PTPRC,VAV1,CD8A,IKBKG,PLCG1,FYN,CD247,IKBKB,ORAI1,MAP3K14,PRF1,CD28
s1p_s1p3_pathway	S1P3 pathway	0.52950268071365	-0.635817051227052	28	15	0.0127551020408163	1176	2242	2768,207,2781,2769,10000,2321,1903,3717,3685,7422,2771,6714,2767,5159,9630	GNA12,AKT1,GNAZ,GNA15,AKT3,FLT1,S1PR3,JAK2,ITGAV,VEGFA,GNAI2,SRC,GNA11,PDGFRB,GNA14
il12_stat4pathway	IL12 signaling mediated by STAT4	0.52950268071365	-0.635817051227052	28	15	0.0127551020408163	1176	2242	3123,3725,920,6775,919,5601,2119,3596,30009,3606,2353,5551,6774,940,3659	HLA-DRB1,JUN,CD4,STAT4,CD247,MAPK9,ETV5,IL13,TBX21,IL18,FOS,PRF1,STAT3,CD28,IRF1
wnt_noncanonical_pathway	Noncanonical Wnt signaling pathway	0.535677299163746	-0.624223353017481	30	16	0.0136054421768707	1176	2242	55636,115908,23118,5601,5590,51701,4773,2316,6093,1855,6885,1452,23002,815,1856,9869	CHD7,CTHRC1,TAB2,MAPK9,PRKCZ,NLK,NFATC2,FLNA,ROCK1,DVL1,MAP3K7,CSNK1A1,DAAM1,CAMK2A,DVL2,SETDB1
ephrinarevpathway	Ephrin A  reverse signaling	0.536784366127511	-0.622158817952376	3	2	0.00170068027210884	1176	2242	1946,2534	EFNA5,FYN
rac1_pathway	RAC1 signaling pathway	0.538819016391113	-0.618375541098602	55	29	0.0246598639455782	1176	2242	10163,5058,5609,1495,10096,8394,26999,9564,1432,4688,10458,5606,23396,3725,999,55845,1499,10811,10092,3984,653361,5601,396,6776,128239,6774,1386,5330,1072	WASF2,PAK1,MAP2K7,CTNNA1,ACTR3,PIP5K1A,CYFIP2,BCAR1,MAPK14,NCF2,BAIAP2,MAP2K3,PIP5K1C,JUN,CDH1,BRK1,CTNNB1,NOXA1,ARPC5,LIMK1,NCF1,MAPK9,ARHGDIA,STAT5A,IQGAP3,STAT3,ATF2,PLCB2,CFL1
plk3_pathway	PLK3 signaling events	0.545964019495077	-0.605202203769289	5	3	0.00255102040816327	1176	2242	1263,995,898	PLK3,CDC25C,CCNE1
bmppathway	BMP receptor signaling	0.552215912341523	-0.593816163636282	36	19	0.016156462585034	1176	2242	285704,10217,4092,8646,4090,8021,6497,197,148738,25805,23645,9241,2932,5499,6885,4091,4089,56963,58190	RGMB,CTDSPL,SMAD7,CHRD,SMAD5,NUP214,SKI,AHSG,HFE2,BAMBI,PPP1R15A,NOG,GSK3B,PPP1CA,MAP3K7,SMAD6,SMAD4,RGMA,CTDSP1
rapid_gr_pathway	Rapid glucocorticoid signaling	0.553605490486606	-0.59130295694136	7	4	0.00340136054421769	1176	2242	2782,5600,1432,5601	GNB1,MAPK11,MAPK14,MAPK9
ecadherin_stabilization_pathway	Stabilization and expansion of the E-cadherin adherens junction	0.561954129518093	-0.576335052494113	40	21	0.0178571428571429	1176	2242	4248,4690,1495,144100,87,360,55740,28964,26999,1729,1956,23396,7791,1499,999,1969,3082,1942,6093,4233,7414	MGAT3,NCK1,CTNNA1,PLEKHA7,ACTN1,AQP3,ENAH,GIT1,CYFIP2,DIAPH1,EGFR,PIP5K1C,ZYX,CTNNB1,CDH1,EPHA2,HGF,EFNA1,ROCK1,MET,VCL
hdac_classi_pathway	Signaling events mediated by HDAC Class I	0.564167934436933	-0.572403315710774	67	35	0.0297619047619048	1176	2242	9612,4149,8850,79885,4092,161882,83933,22933,25942,10013,7329,5566,4084,9734,54815,23381,23408,51564,8932,4790,10419,6774,57459,9219,8841,5905,53615,2287,7514,9759,4792,7132,7528,3066,8945	NCOR2,MAX,KAT2B,HDAC11,SMAD7,ZFPM1,HDAC10,SIRT2,SIN3A,HDAC6,UBE2I,PRKACA,MXD1,HDAC9,GATAD2A,SMG5,SIRT5,HDAC7,MBD2,NFKB1,PRMT5,STAT3,GATAD2B,MTA2,HDAC3,RANGAP1,MBD3,FKBP3,XPO1,HDAC4,NFKBIA,TNFRSF1A,YY1,HDAC2,BTRC
hnf3bpathway	FOXA2 and FOXA3 transcription factor networks	0.570900996667503	-0.560539470230468	44	23	0.0195578231292517	1176	2242	2147,207,2908,3484,5313,7037,3630,1051,6833,3170,3157,3033,3651,2645,622,5105,3767,1385,37,3172,1052,6667,8788	F2,AKT1,NR3C1,IGFBP1,PKLR,TFRC,INS,CEBPB,ABCC8,FOXA2,HMGCS1,HADH,PDX1,GCK,BDH1,PCK1,KCNJ11,CREB1,ACADVL,HNF4A,CEBPD,SP1,DLK1
arf6downstreampathway	Arf6 downstream pathway	0.576887454289938	-0.550108084723069	15	8	0.00680272108843537	1176	2242	9727,5329,5338,5337,375,8394,7074,8766	RAB11FIP3,PLAUR,PLD2,PLD1,ARF1,PIP5K1A,TIAM1,RAB11A
s1p_meta_pathway	Sphingosine 1-phosphate (S1P) pathway	0.590444920401614	-0.526878923899087	21	11	0.00935374149659864	1176	2242	2768,53637,2781,2769,1903,8877,8698,56848,2771,2767,9630	GNA12,S1PR5,GNAZ,GNA15,S1PR3,SPHK1,S1PR4,SPHK2,GNAI2,GNA11,GNA14
trkrpathway	Neurotrophic factor-mediated Trk receptor signaling	0.594238574041677	-0.520474400454363	56	29	0.0246598639455782	1176	2242	391,5058,5923,2889,1793,10287,5295,4909,4914,10755,6016,4804,25759,25,595,1399,5335,6464,8878,53358,23263,9093,5781,5590,5290,30844,6774,7074,4915	RHOG,PAK1,RASGRF1,RAPGEF1,DOCK1,RGS19,PIK3R1,NTF4,NTRK1,GIPC1,RIT1,NGFR,SHC2,ABL1,CCND1,CRKL,PLCG1,SHC1,SQSTM1,SHC3,MCF2L,DNAJA3,PTPN11,PRKCZ,PIK3CA,EHD4,STAT3,TIAM1,NTRK2
lymphangiogenesis_pathway	VEGFR3 signaling in lymphatic endothelium	0.594521803991985	-0.519997887338852	23	12	0.0102040816326531	1176	2242	207,2335,2324,1277,6195,5295,3688,5290,5600,1385,3672,1432	AKT1,FN1,FLT4,COL1A1,RPS6KA1,PIK3R1,ITGB1,PIK3CA,MAPK11,CREB1,ITGA1,MAPK14
erbb1_receptor_proximal_pathway	EGF receptor (ErbB1) signaling pathway	0.598424497422337	-0.513454914954037	25	13	0.0110544217687075	1176	2242	5058,2934,5335,5770,7094,5777,5295,5781,5290,6774,6714,1956,23396	PAK1,GSN,PLCG1,PTPN1,TLN1,PTPN6,PIK3R1,PTPN11,PIK3CA,STAT3,SRC,EGFR,PIP5K1C
bcr_5pathway	BCR signaling pathway	0.610820397129526	-0.492952312073545	66	34	0.0289115646258503	1176	2242	7189,5894,7410,2113,4067,1432,3725,973,6464,933,3551,5336,4790,27071,5290,6885,6850,818,5170,2213,207,5777,974,5295,10892,4772,2353,29760,5788,9467,8517,4792,5533,3265	TRAF6,RAF1,VAV2,ETS1,LYN,MAPK14,JUN,CD79A,SHC1,CD22,IKBKB,PLCG2,NFKB1,DAPP1,PIK3CA,MAP3K7,SYK,CAMK2G,PDPK1,FCGR2B,AKT1,PTPN6,CD79B,PIK3R1,MALT1,NFATC1,FOS,BLNK,PTPRC,SH3BP5,IKBKG,NFKBIA,PPP3CC,HRAS
il1pathway	IL1-mediated signaling events	0.615913992744616	-0.48464794736453	35	18	0.0153061224489796	1176	2242	4215,7189,387522,5295,54472,3725,3554,8517,8878,3654,23118,4790,3551,5290,5590,3557,6885,100302736	MAP3K3,TRAF6,TMEM189-UBE2V1,PIK3R1,TOLLIP,JUN,IL1R1,IKBKG,SQSTM1,IRAK1,TAB2,NFKB1,IKBKB,PIK3CA,PRKCZ,IL1RN,MAP3K7,TMED7-TICAM2
rac1_reg_pathway	Regulation of RAC1 activity	0.622179400662922	-0.474526802326506	39	20	0.0170068027210884	1176	2242	613,5923,10451,1793,8874,10928,7204,7410,57580,1794,29,7409,1124,64333,396,9181,392,7074,57572,50619	BCR,RASGRF1,VAV3,DOCK1,ARHGEF7,RALBP1,TRIO,VAV2,PREX1,DOCK2,ABR,VAV1,CHN2,ARHGAP9,ARHGDIA,ARHGEF2,ARHGAP1,TIAM1,DOCK6,DEF6
hnf3apathway	FOXA1 transcription factor network	0.628121492650811	-0.465021671589791	43	22	0.0187074829931973	1176	2242	6647,5451,80781,7356,672,6441,2353,725,3630,23761,1051,3725,7031,3170,5265,7448,6469,4782,4731,7026,8204,6667	SOD1,POU2F1,COL18A1,SCGB1A1,BRCA1,SFTPD,FOS,C4BPB,INS,PISD,CEBPB,JUN,TFF1,FOXA2,SERPINA1,VTN,SHH,NFIC,NDUFV3,NR2F2,NRIP1,SP1
tgfbrpathway	TGF-beta receptor signaling	0.639198972567609	-0.44753949190369	51	26	0.022108843537415	1176	2242	5170,83658,4092,7046,857,168002,7531,7048,4088,2280,5515,7049,4087,1601,1499,6464,1616,25805,8312,23645,11059,6198,5499,6885,4089,815	PDPK1,DYNLRB1,SMAD7,TGFBR1,CAV1,DACT2,YWHAE,TGFBR2,SMAD3,FKBP1A,PPP2CA,TGFBR3,SMAD2,DAB2,CTNNB1,SHC1,DAXX,BAMBI,AXIN1,PPP1R15A,WWP1,RPS6KB1,PPP1CA,MAP3K7,SMAD4,CAMK2A
tcr_pathway	TCR signaling in naive CD4+ T cells	0.651831067148364	-0.42796985009325	61	31	0.0263605442176871	1176	2242	5170,7189,6452,920,207,4690,942,5777,1326,10892,83593,2316,867,3937,5578,5788,3123,7409,8517,5335,2534,7454,6464,84174,919,3551,5781,84876,27347,9020,940	PDPK1,TRAF6,SH3BP2,CD4,AKT1,NCK1,CD86,PTPN6,MAP3K8,MALT1,RASSF5,FLNA,CBL,LCP2,PRKCA,PTPRC,HLA-DRB1,VAV1,IKBKG,PLCG1,FYN,WAS,SHC1,SLA2,CD247,IKBKB,PTPN11,ORAI1,STK39,MAP3K14,CD28
alk1pathway	ALK1 signaling events	0.673214295144321	-0.395691582273705	24	12	0.0102040816326531	1176	2242	2280,3397,90,94,4092,7046,4090,2658,5499,857,7048,4089	FKBP1A,ID1,ACVR1,ACVRL1,SMAD7,TGFBR1,SMAD5,GDF2,PPP1CA,CAV1,TGFBR2,SMAD4
erbb4_pathway	ErbB4 signaling events	0.677047789236842	-0.390013418846513	32	16	0.0136054421768707	1176	2242	685,6868,1839,5295,2064,10718,2534,6464,863,23118,51741,5618,5290,11059,3717,6776	BTC,ADAM17,HBEGF,PIK3R1,ERBB2,NRG3,FYN,SHC1,CBFA2T3,TAB2,WWOX,PRLR,PIK3CA,WWP1,JAK2,STAT5A
hif2pathway	HIF-2-alpha transcription factor network	0.67829461500948	-0.388173550012701	34	17	0.0144557823129252	1176	2242	6923,2034,6513,3646,6921,8553,7422,2113,112398,5230,2321,4323,5054,1942,405,54583,6667	TCEB2,EPAS1,SLC2A1,EIF3E,TCEB1,BHLHE40,VEGFA,ETS1,EGLN2,PGK1,FLT1,MMP14,SERPINE1,EFNA1,ARNT,EGLN1,SP1
cxcr3pathway	CXCR3-mediated signaling events	0.67829461500948	-0.388173550012701	34	17	0.0144557823129252	1176	2242	5170,207,2475,5894,5295,79109,2782,1432,6714,5605,5606,3689,5290,408,5600,2771,64223	PDPK1,AKT1,MTOR,RAF1,PIK3R1,MAPKAP1,GNB1,MAPK14,SRC,MAP2K2,MAP2K3,ITGB2,PIK3CA,ARRB1,MAPK11,GNAI2,MLST8
ret_pathway	Signaling events regulated by Ret tyrosine kinase	0.680985895056138	-0.384213685152648	38	19	0.016156462585034	1176	2242	9260,5829,4690,5295,5979,5578,85358,9564,5566,6714,3725,6464,2886,5290,5781,2668,2887,1385,3265	PDLIM7,PXN,NCK1,PIK3R1,RET,PRKCA,SHANK3,BCAR1,PRKACA,SRC,JUN,SHC1,GRB7,PIK3CA,PTPN11,GDNF,GRB10,CREB1,HRAS
hes_heypathway	Notch-mediated HES/HEY network	0.688368914557132	-0.373430371740536	48	24	0.0204081632653061	1176	2242	3280,4851,9612,2548,920,3397,860,142,2626,632,6929,55502,817,2627,3091,4654,7088,3717,3516,7528,9794,6774,1487,405	HES1,NOTCH1,NCOR2,GAA,CD4,ID1,RUNX2,PARP1,GATA4,BGLAP,TCF3,HES6,CAMK2D,GATA6,HIF1A,MYOD1,TLE1,JAK2,RBPJ,YY1,MAML1,STAT3,CTBP1,ARNT
s1p_s1p5_pathway	S1P5 pathway	0.689251204829266	-0.372149481050356	8	4	0.00340136054421769	1176	2242	2768,53637,2781,2771	GNA12,S1PR5,GNAZ,GNAI2
et_egfrpathway	EGFR-dependent Endothelin signaling events	0.689251204829266	-0.372149481050356	8	4	0.00340136054421769	1176	2242	2475,3265,1956,1906	MTOR,HRAS,EGFR,EDN1
glypican_3pathway	Glypican 3 network	0.689251204829266	-0.372149481050356	8	4	0.00340136054421769	1176	2242	5727,5601,6469,5045	PTCH1,MAPK9,SHH,FURIN
il2_1pathway	IL2-mediated signaling events	0.691448116689635	-0.368967160786749	52	26	0.022108843537415	1176	2242	5894,5295,8835,3560,2353,1432,5605,9021,3725,9261,1154,2534,8651,6464,10254,4609,5601,5290,5781,2185,6776,5600,9046,6774,6850,5528	RAF1,PIK3R1,SOCS2,IL2RB,FOS,MAPK14,MAP2K2,SOCS3,JUN,MAPKAPK2,CISH,FYN,SOCS1,SHC1,STAM2,MYC,MAPK9,PIK3CA,PTPN11,PTK2B,STAT5A,MAPK11,DOK2,STAT3,SYK,PPP2R5D
plk_pathway	Polo-like kinase signaling events in the cell cycle	0.723548586316626	-0.323587580615778	4	2	0.00170068027210884	1176	2242	1263,10733	PLK3,PLK4
aurora_b_pathway	Aurora B signaling	0.736852064732262	-0.305368133220173	39	19	0.016156462585034	1176	2242	1058,5684,10112,6867,8452,4869,9493,4691,7431,11004,10592,3925,7813,4638,699,151648,23468,3619,5528	CENPA,PSMA3,KIF20A,TACC1,CUL3,NPM1,KIF23,NCL,VIM,KIF2C,SMC2,STMN1,EVI5,MYLK,BUB1,SGOL1,CBX5,INCENP,PPP2R5D
nfat_3pathway	Role of Calcineurin-dependent NFAT signaling in lymphocytes	0.738658464114238	-0.302919624383215	51	25	0.0212585034013605	1176	2242	3164,1326,10971,4773,4209,7531,5578,1452,8021,5566,1432,4772,5583,2280,7514,4775,5580,5601,5590,2932,23523,7534,5292,3837,2810	NR4A1,MAP3K8,YWHAQ,NFATC2,MEF2D,YWHAE,PRKCA,CSNK1A1,NUP214,PRKACA,MAPK14,NFATC1,PRKCH,FKBP1A,XPO1,NFATC3,PRKCD,MAPK9,PRKCZ,GSK3B,CABIN1,YWHAZ,PIM1,KPNB1,SFN
trail_pathway	TRAIL signaling pathway	0.742251031503513	-0.298067775641001	25	12	0.0102040816326531	1176	2242	8517,7818,7186,5295,6609,3551,5290,8737,8743,8793,8772,8837	IKBKG,DAP3,TRAF2,PIK3R1,SMPD1,IKBKB,PIK3CA,RIPK1,TNFSF10,TNFRSF10D,FADD,CFLAR
rhodopsin_pathway	Visual signal transduction: Rods	0.744409046795124	-0.295164601150969	23	11	0.00935374149659864	1176	2242	8787,3000,5145,5959,2782,2779,388531,2978,5158,6011,9227	RGS9,GUCY2D,PDE6A,RDH5,GNB1,GNAT1,RGS9BP,GUCA1A,PDE6B,GRK1,LRAT
smad2_3pathway	Regulation of cytoplasmic and nuclear SMAD2/3 signaling	0.750693748496073	-0.286757502004029	19	9	0.0076530612244898	1176	2242	51588,4088,4087,10217,7329,8021,4089,3837,58190	PIAS4,SMAD3,SMAD2,CTDSPL,UBE2I,NUP214,SMAD4,KPNB1,CTDSP1
glypican_2pathway	Glypican 2 network	0.774041154201498	-0.256130236002958	2	1	0.000850340136054422	1176	2242	4192	MDK
plk2_4pathway	PLK2 and PLK4 events	0.774041154201498	-0.256130236002958	2	1	0.000850340136054422	1176	2242	10733	PLK4
tcrraspathway	Ras signaling in the CD4+ TCR pathway	0.778653463714124	-0.250189179692468	11	5	0.00425170068027211	1176	2242	5578,2353,5894,1326,5778	PRKCA,FOS,RAF1,MAP3K8,PTPN7
ranbp2pathway	Sumoylation by RanBP2 regulates transcriptional repression	0.778653463714124	-0.250189179692468	11	5	0.00425170068027211	1176	2242	5905,8554,7514,9759,7329	RANGAP1,PIAS1,XPO1,HDAC4,UBE2I
alk2pathway	ALK2 signaling events	0.778653463714124	-0.250189179692468	11	5	0.00425170068027211	1176	2242	2280,4090,90,4089,268	FKBP1A,SMAD5,ACVR1,SMAD4,AMH
caspase_pathway	Caspase cascade in apoptosis	0.782673081154185	-0.245040191053325	50	24	0.0204081632653061	1176	2242	1677,142,330,839,7186,8737,7431,54205,637,6304,351,329,4000,4926,2934,4001,3984,58,7020,7132,6720,317,5551,7150	DFFB,PARP1,BIRC3,CASP6,TRAF2,RIPK1,VIM,CYCS,BID,SATB1,APP,BIRC2,LMNA,NUMA1,GSN,LMNB1,LIMK1,ACTA1,TFAP2A,TNFRSF1A,SREBF1,APAF1,PRF1,TOP1
cd8tcrdownstreampathway	Downstream signaling in naive CD8+ T cells	0.782673081154185	-0.245040191053325	50	24	0.0204081632653061	1176	2242	1958,5894,6775,567,4773,3454,3560,5578,2353,4772,5605,3105,3725,925,4775,8320,919,3726,5601,5778,356,7293,8061,5551	EGR1,RAF1,STAT4,B2M,NFATC2,IFNAR1,IL2RB,PRKCA,FOS,NFATC1,MAP2K2,HLA-A,JUN,CD8A,NFATC3,EOMES,CD247,JUNB,MAPK9,PTPN7,FASLG,TNFRSF4,FOSL1,PRF1
s1p_s1p2_pathway	S1P2 pathway	0.804650759731481	-0.217346934541753	24	11	0.00935374149659864	1176	2242	5058,3725,2768,2781,2769,1003,2353,1432,2771,2767,9630	PAK1,JUN,GNA12,GNAZ,GNA15,CDH5,FOS,MAPK14,GNAI2,GNA11,GNA14
s1p_s1p1_pathway	S1P1 pathway	0.81463851791868	-0.20501080042869	20	9	0.0076530612244898	1176	2242	5335,5743,2781,8877,3685,7422,5330,2771,5159	PLCG1,PTGS2,GNAZ,SPHK1,ITGAV,VEGFA,PLCB2,GNAI2,PDGFRB
e2f_pathway	E2F transcription factor network	0.816845553335969	-0.202305243197119	73	35	0.0297619047619048	1176	2242	9134,8850,1026,898,7161,26959,4609,896,5902,10419,6667,23429,6595,993,2648,1871,4605,1066,6241,4170,990,3090,672,10155,983,5933,7027,472,5054,317,7029,7528,23468,1870,4172	CCNE2,KAT2B,CDKN1A,CCNE1,TP73,HBP1,MYC,CCND3,RANBP1,PRMT5,SP1,RYBP,SMARCA2,CDC25A,KAT2A,E2F3,MYBL2,CES1,RRM2,MCL1,CDC6,HIC1,BRCA1,TRIM28,CDK1,RBL1,TFDP1,ATM,SERPINE1,APAF1,TFDP2,YY1,CBX5,E2F2,MCM3
il23pathway	IL23-mediated signaling events	0.83277072018337	-0.182996920580701	37	17	0.0144557823129252	1176	2242	920,6775,5295,3606,29949,4353,7297,9021,3675,4790,4792,11009,5290,6776,3717,6774,4843	CD4,STAT4,PIK3R1,IL18,IL19,MPO,TYK2,SOCS3,ITGA3,NFKB1,NFKBIA,IL24,PIK3CA,STAT5A,JAK2,STAT3,NOS2
syndecan_2_pathway	Syndecan-2-mediated signaling events	0.838072555189221	-0.176650600876619	33	15	0.0127551020408163	1176	2242	3909,2048,2335,5580,4313,3576,3688,10399,6386,1437,5566,284217,3265,6714,23495	LAMA3,EPHB2,FN1,PRKCD,MMP2,IL8,ITGB1,GNB2L1,SDCBP,CSF2,PRKACA,LAMA1,HRAS,SRC,TNFRSF13B
s1p_s1p4_pathway	S1P4 pathway	0.838706215780343	-0.175894793811004	14	6	0.00510204081632653	1176	2242	2768,8698,5335,53637,2781,2771	GNA12,S1PR4,PLCG1,S1PR5,GNAZ,GNAI2
insulin_glucose_pathway	Insulin-mediated glucose transport	0.844874251535785	-0.168567477449527	29	13	0.0110544217687075	1176	2242	3643,207,4012,5506,5590,10971,2932,2997,7534,7531,9882,3630,2810	INSR,AKT1,LNPEP,PPP1R3A,PRKCZ,YWHAQ,GSK3B,GYS1,YWHAZ,YWHAE,TBC1D4,INS,SFN
cone_pathway	Visual signal transduction: Cones	0.859054296370007	-0.151923150182894	23	10	0.00850340136054422	1176	2242	8787,3000,2793,5959,388531,2978,6011,54714,9227,131890	RGS9,GUCY2D,GNGT2,RDH5,RGS9BP,GUCA1A,GRK1,CNGB3,LRAT,GRK7
ceramide_pathway	Ceramide signaling pathway	0.862401355821851	-0.148034506678998	44	20	0.0170068027210884	1176	2242	207,330,7186,5894,6609,8737,54205,8575,637,5605,8772,5154,4609,5580,4790,4792,7132,5590,1509,56848	AKT1,BIRC3,TRAF2,RAF1,SMPD1,RIPK1,CYCS,PRKRA,BID,MAP2K2,FADD,PDGFA,MYC,PRKCD,NFKB1,NFKBIA,TNFRSF1A,PRKCZ,CTSD,SPHK2
syndecan_3_pathway	Syndecan-3-mediated signaling events	0.880730418595475	-0.127003694655711	17	7	0.00595238095238095	1176	2242	9672,2534,2017,51107,6714,1956,3576	SDC3,FYN,CTTN,APH1A,SRC,EGFR,IL8
nephrin_neph1_pathway	Nephrin/Neph1 signaling in the kidney podocyte	0.892453612066368	-0.113780741954882	26	11	0.00935374149659864	1176	2242	3725,5335,2534,207,4690,5295,5601,5290,7827,7082,55243	JUN,PLCG1,FYN,AKT1,NCK1,PIK3R1,MAPK9,PIK3CA,NPHS2,TJP1,KIRREL
glypicanpathway	Glypican pathway	0.892669548246603	-0.113538813346157	3	1	0.000850340136054422	1176	2242	2817	GPC1
aurora_c_pathway	Aurora C signaling	0.892669548246603	-0.113538813346157	3	1	0.000850340136054422	1176	2242	3619	INCENP
a4b1_a4b7_pathway	a4b1 and a4b7 Integrin signaling	0.892669548246603	-0.113538813346157	3	1	0.000850340136054422	1176	2242	3688	ITGB1
hnf3pathway	FOXA transcription factor networks	0.892669548246603	-0.113538813346157	3	1	0.000850340136054422	1176	2242	3170	FOXA2
tcrjnkpathway	JNK signaling in the CD4+ TCR pathway	0.902062690031904	-0.103071260190589	13	5	0.00425170068027211	1176	2242	1399,3725,6885,3937,1326	CRKL,JUN,MAP3K7,LCP2,MAP3K8
ar_tf_pathway	Regulation of Androgen receptor activity	0.912062173504819	-0.0920471185288066	50	22	0.0187074829931973	1176	2242	6595,1958,8850,8805,2908,11143,5451,10399,5585,1432,6714,3817,3725,10919,51564,2932,3320,25803,5152,10499,10498,83637	SMARCA2,EGR1,KAT2B,TRIM24,NR3C1,KAT7,POU2F1,GNB2L1,PKN1,MAPK14,SRC,KLK2,JUN,EHMT2,HDAC7,GSK3B,HSP90AA1,SPDEF,PDE9A,NCOA2,CARM1,ZMIZ2
p75ntrpathway	p75(NTR)-mediated signaling	0.923435072036299	-0.0796547882180282	61	27	0.0229591836734694	1176	2242	7189,6868,207,839,51107,5295,4909,5045,57142,54205,4099,7531,4804,351,56160,8517,3654,8878,6464,11108,5601,3551,396,5590,5290,317,65078	TRAF6,ADAM17,AKT1,CASP6,APH1A,PIK3R1,NTF4,FURIN,RTN4,CYCS,MAG,YWHAE,NGFR,APP,NDNL2,IKBKG,IRAK1,SQSTM1,SHC1,PRDM4,MAPK9,IKBKB,ARHGDIA,PRKCZ,PIK3CA,APAF1,RTN4R
il2_stat5pathway	IL2 signaling events mediated by STAT5	0.940715608602656	-0.0611144076015907	30	12	0.0102040816326531	1176	2242	6464,4609,5295,896,5781,3565,5290,356,6776,3560,5551,6667	SHC1,MYC,PIK3R1,CCND3,PTPN11,IL4,PIK3CA,FASLG,STAT5A,IL2RB,PRF1,SP1
il27pathway	IL27-mediated signaling events	0.949247771321781	-0.0520854277036049	26	10	0.00850340136054422	1176	2242	246778,6775,3572,2625,30009,6776,3606,3717,6774,7297	IL27,STAT4,IL6ST,GATA3,TBX21,STAT5A,IL18,JAK2,STAT3,TYK2
anthraxpathway	Cellular roles of Anthrax toxin	0.958986202246646	-0.0418785918490775	22	8	0.00680272108843537	1176	2242	728358,118429,1667,5609,22861,3606,5605,5606	DEFA1B,ANTXR2,DEFA1,MAP2K7,NLRP1,IL18,MAP2K2,MAP2K3
il2_pi3kpathway	IL2 signaling events mediated by PI3K	0.975334898880377	-0.0249743809309556	37	14	0.0119047619047619	1176	2242	207,6464,7015,2475,4609,5295,6609,4790,5781,5590,5290,6198,3320,3560	AKT1,SHC1,TERT,MTOR,MYC,PIK3R1,SMPD1,NFKB1,PTPN11,PRKCZ,PIK3CA,RPS6KB1,HSP90AA1,IL2RB
lis1pathway	Lissencephaly gene (LIS1) in neuronal migration and development	0.981914297371705	-0.0182512479884644	31	11	0.00935374149659864	1176	2242	25,1778,1020,4043,5050,5049,7531,7804,5528,8851,10726	ABL1,DYNC1H1,CDK5,LRPAP1,PAFAH1B3,PAFAH1B2,YWHAE,LRP8,PPP2R5D,CDK5R1,NUDC
botulinumtoxinpathway	Effects of Botulinum toxin	0.986575043507742	-0.01351588595374	9	2	0.00170068027210884	1176	2242	25782,6804	RAB3GAP2,STX1A
hdac_classiii_pathway	Signaling events mediated by HDAC Class III	0.998273078792818	-0.00172841405454361	39	12	0.0102040816326531	1176	2242	7280,9759,8370,8850,55902,2274,4654,4209,22933,1026,84532,10376	TUBB2A,HDAC4,HIST2H4A,KAT2B,ACSS2,FHL2,MYOD1,MEF2D,SIRT2,CDKN1A,ACSS1,TUBA1B
aurora_kinase_pathway	Signaling by Aurora kinases	0.999999999996965	-3.03498892684217e-12	3	0	0	1176	2242
pi3kcibpathway	Class IB PI3K non-lipid kinase events	0.999999999996965	-3.03498892684217e-12	3	0	0	1176	2242