TermID	Term	Enrichment	logP	Genes in Term	Target Genes in Term	Fraction of Targets in Term	Total Target Genes	Total Genes	Entrez Gene IDs	Gene Symbols
R-HSA-112043	PLC beta mediated events	0.000543213571383211	-7.5180079978949	47	5	0.0337837837837838	148	10287	3709,5578,2775,5580,107	ITPR2,PRKCA,GNAO1,PRKCD,ADCY1
R-HSA-8849471	PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases	0.000558005897707999	-7.49114102626964	27	4	0.027027027027027	148	10287	153090,5829,9462,1793	DAB2IP,PXN,RASAL2,DOCK1
R-HSA-112040	G-protein mediated events	0.000599430181123762	-7.41953105212418	48	5	0.0337837837837838	148	10287	3709,5578,2775,5580,107	ITPR2,PRKCA,GNAO1,PRKCD,ADCY1
R-HSA-1489509	DAG and IP3 signaling	0.00136386252076439	-6.5974345158691	34	4	0.027027027027027	148	10287	3709,5578,5580,107	ITPR2,PRKCA,PRKCD,ADCY1
R-HSA-111885	Opioid Signalling	0.00137736902214932	-6.5875801051971	85	6	0.0405405405405405	148	10287	3709,5144,5578,2775,5580,107	ITPR2,PDE4D,PRKCA,GNAO1,PRKCD,ADCY1
R-HSA-167021	PLC-gamma1 signalling	0.00169420980538709	-6.38053883836281	36	4	0.027027027027027	148	10287	3709,5578,5580,107	ITPR2,PRKCA,PRKCD,ADCY1
R-HSA-212718	EGFR interacts with phospholipase C-gamma	0.00169420980538709	-6.38053883836281	36	4	0.027027027027027	148	10287	3709,5578,5580,107	ITPR2,PRKCA,PRKCD,ADCY1
R-HSA-4086398	Ca2+ pathway	0.00179344258791374	-6.32361827270378	61	5	0.0337837837837838	148	10287	83439,7481,3709,5578,2775	TCF7L1,WNT11,ITPR2,PRKCA,GNAO1
R-HSA-4420097	VEGFA-VEGFR2 Pathway	0.00285695359597386	-5.85799939808667	330	12	0.0810810810810811	148	10287	54756,57761,5829,9462,1850,1793,5924,5580,153090,5603,3709,5578	IL17RD,TRIB3,PXN,RASAL2,DUSP8,DOCK1,RASGRF2,PRKCD,DAB2IP,MAPK13,ITPR2,PRKCA
R-HSA-2028269	Signaling by Hippo	0.00320919927925673	-5.74173381867138	21	3	0.0202702702702703	148	10287	23286,60485,25937	WWC1,SAV1,WWTR1
R-HSA-194138	Signaling by VEGF	0.00346967148417701	-5.66369536265299	338	12	0.0810810810810811	148	10287	54756,57761,5829,9462,1850,1793,5924,5580,153090,5603,3709,5578	IL17RD,TRIB3,PXN,RASAL2,DUSP8,DOCK1,RASGRF2,PRKCD,DAB2IP,MAPK13,ITPR2,PRKCA
R-HSA-4411364	Binding of TCF/LEF:CTNNB1 to target gene promoters	0.00411776814216476	-5.49244397546704	7	2	0.0135135135135135	148	10287	83439,4609	TCF7L1,MYC
R-HSA-418597	G alpha (z) signalling events	0.00489914905833806	-5.31869375051013	48	4	0.027027027027027	148	10287	26575,5578,5580,107	RGS17,PRKCA,PRKCD,ADCY1
R-HSA-450520	HuR (ELAVL1) binds and stabilizes mRNA	0.00543869164772513	-5.21421675297336	8	2	0.0135135135135135	148	10287	5578,5580	PRKCA,PRKCD
R-HSA-422475	Axon guidance	0.00550587961501675	-5.20193873682753	549	16	0.108108108108108	148	10287	54756,6331,9462,1850,9826,1793,5362,1944,5578,5217,785,4756,5924,57522,153090,2051	IL17RD,SCN5A,RASAL2,DUSP8,ARHGEF11,DOCK1,PLXNA2,EFNA3,PRKCA,PFN2,CACNB4,NEO1,RASGRF2,SRGAP1,DAB2IP,EPHB6
R-HSA-114508	Effects of PIP2 hydrolysis	0.0066273896589632	-5.0165442689079	27	3	0.0202702702702703	148	10287	3709,57406,5580	ITPR2,ABHD6,PRKCD
R-HSA-111933	Calmodulin induced events	0.00734542260323736	-4.91367793483208	28	3	0.0202702702702703	148	10287	5578,5580,107	PRKCA,PRKCD,ADCY1
R-HSA-111997	CaM pathway	0.00734542260323736	-4.91367793483208	28	3	0.0202702702702703	148	10287	5578,5580,107	PRKCA,PRKCD,ADCY1
R-HSA-8866904	Negative regulation of activity of TFAP2 (AP-2) family transcription factors	0.00857730153709007	-4.75863592111636	10	2	0.0135135135135135	148	10287	79047,284252	KCTD15,KCTD1
R-HSA-111996	Ca-dependent events	0.0089149918381841	-4.72002094318242	30	3	0.0202702702702703	148	10287	5578,5580,107	PRKCA,PRKCD,ADCY1
R-HSA-6794361	Interactions of neurexins and neuroligins at synapses	0.00956637846606037	-4.64950057083737	58	4	0.027027027027027	148	10287	57502,57669,321,6812	NLGN4X,EPB41L5,APBA2,STXBP1
R-HSA-70171	Glycolysis	0.0106662399546008	-4.54067166990689	32	3	0.0202702702702703	148	10287	2597,226,3099	GAPDH,ALDOA,HK2
R-HSA-8848021	Signaling by PTK6	0.0156558216453894	-4.15691244104642	67	4	0.027027027027027	148	10287	153090,5829,9462,1793	DAB2IP,PXN,RASAL2,DOCK1
R-HSA-177929	Signaling by EGFR	0.0159005347475817	-4.14140253839811	364	11	0.0743243243243243	148	10287	54756,57761,5829,9462,1850,5924,5580,107,153090,3709,5578	IL17RD,TRIB3,PXN,RASAL2,DUSP8,RASGRF2,PRKCD,ADCY1,DAB2IP,ITPR2,PRKCA
R-HSA-194840	Rho GTPase cycle	0.0171147703845741	-4.06781342312422	143	6	0.0405405405405405	148	10287	79822,23092,9826,5924,26230,57522	ARHGAP28,ARHGAP26,ARHGEF11,RASGRF2,TIAM2,SRGAP1
R-HSA-8864260	Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors	0.0195503461517258	-3.93476228673688	40	3	0.0202702702702703	148	10287	79047,4609,284252	KCTD15,MYC,KCTD1
R-HSA-6794362	Protein-protein interactions at synapses	0.0198945264535693	-3.91731063767005	72	4	0.027027027027027	148	10287	57502,57669,321,6812	NLGN4X,EPB41L5,APBA2,STXBP1
R-HSA-166520	Signalling by NGF	0.019921136485106	-3.91597397598796	477	13	0.0878378378378378	148	10287	54756,57761,9462,1850,9826,5924,5580,107,153090,5603,3709,5578,26230	IL17RD,TRIB3,RASAL2,DUSP8,ARHGEF11,RASGRF2,PRKCD,ADCY1,DAB2IP,MAPK13,ITPR2,PRKCA,TIAM2
R-HSA-76002	Platelet activation, signaling and aggregation	0.0205641924139992	-3.8842039479955	282	9	0.0608108108108108	148	10287	5768,5777,226,5580,2621,3709,5578,5874,57406	QSOX1,PTPN6,ALDOA,PRKCD,GAS6,ITPR2,PRKCA,RAB27B,ABHD6
R-HSA-1433559	Regulation of KIT signaling	0.0216191473125954	-3.83417590729929	16	2	0.0135135135135135	148	10287	5578,5777	PRKCA,PTPN6
R-HSA-163685	Integration of energy metabolism	0.0218698008365796	-3.82264855102996	111	5	0.0337837837837838	148	10287	402,3709,5578,6812,107	ARL2,ITPR2,PRKCA,STXBP1,ADCY1
R-HSA-6802957	Oncogenic MAPK signaling	0.022746346665412	-3.78335073261625	75	4	0.027027027027027	148	10287	80853,153090,9462,57670	KDM7A,DAB2IP,RASAL2,KIAA1549
R-HSA-187037	NGF signalling via TRKA from the plasma membrane	0.0238232402489624	-3.73709369370335	387	11	0.0743243243243243	148	10287	54756,57761,9462,1850,5924,5580,107,153090,5603,3709,5578	IL17RD,TRIB3,RASAL2,DUSP8,RASGRF2,PRKCD,ADCY1,DAB2IP,MAPK13,ITPR2,PRKCA
R-HSA-189445	Metabolism of porphyrins	0.0242735222794739	-3.71836914082969	17	2	0.0135135135135135	148	10287	7390,645	UROS,BLVRB
R-HSA-264642	Acetylcholine Neurotransmitter Release Cycle	0.0242735222794739	-3.71836914082969	17	2	0.0135135135135135	148	10287	8497,6812	PPFIA4,STXBP1
R-HSA-432142	Platelet sensitization by LDL	0.0242735222794739	-3.71836914082969	17	2	0.0135135135135135	148	10287	2268,5777	FGR,PTPN6
R-HSA-5633008	TP53 Regulates Transcription of Cell Death Genes	0.0266626577859981	-3.62449127730258	45	3	0.0202702702702703	148	10287	8794,5366,665	TNFRSF10C,PMAIP1,BNIP3L
R-HSA-181430	Norepinephrine Neurotransmitter Release Cycle	0.0270537022128359	-3.60993141751566	18	2	0.0135135135135135	148	10287	8497,6812	PPFIA4,STXBP1
R-HSA-181429	Serotonin Neurotransmitter Release Cycle	0.0270537022128359	-3.60993141751566	18	2	0.0135135135135135	148	10287	8497,6812	PPFIA4,STXBP1
R-HSA-397014	Muscle contraction	0.0278845718368725	-3.57968172386232	204	7	0.0472972972972973	148	10287	59,6331,29767,3709,5829,785,25937	ACTA2,SCN5A,TMOD2,ITPR2,PXN,CACNB4,WWTR1
R-HSA-422356	Regulation of insulin secretion	0.0280280871128604	-3.57454816041316	80	4	0.027027027027027	148	10287	402,3709,5578,6812	ARL2,ITPR2,PRKCA,STXBP1
R-HSA-916853	Degradation of GABA	0.0285685712141311	-3.55544807399591	2	1	0.00675675675675676	148	10287	18	ABAT
R-HSA-6804754	Regulation of TP53 Expression	0.0285685712141311	-3.55544807399591	2	1	0.00675675675675676	148	10287	639	PRDM1
R-HSA-112316	Neuronal System	0.0290921465596157	-3.53728701890466	349	10	0.0675675675675676	148	10287	57669,5924,107,57502,8497,18,5578,321,6812,785	EPB41L5,RASGRF2,ADCY1,NLGN4X,PPFIA4,ABAT,PRKCA,APBA2,STXBP1,CACNB4
R-HSA-888590	GABA synthesis, release, reuptake and degradation	0.0299555696629064	-3.5080400063376	19	2	0.0135135135135135	148	10287	18,6812	ABAT,STXBP1
R-HSA-186763	Downstream signal transduction	0.0306036586619505	-3.48663571305499	352	10	0.0675675675675676	148	10287	54756,57761,9462,1850,5924,5580,107,153090,3709,5578	IL17RD,TRIB3,RASAL2,DUSP8,RASGRF2,PRKCD,ADCY1,DAB2IP,ITPR2,PRKCA
R-HSA-2424491	DAP12 signaling	0.0327047133994519	-3.42023607081017	356	10	0.0675675675675676	148	10287	54756,57761,9462,1850,5924,5580,107,153090,3709,5578	IL17RD,TRIB3,RASAL2,DUSP8,RASGRF2,PRKCD,ADCY1,DAB2IP,ITPR2,PRKCA
R-HSA-5218921	VEGFR2 mediated cell proliferation	0.0327632528264114	-3.41844773230096	258	8	0.0540540540540541	148	10287	54756,9462,1850,5924,5580,153090,3709,5578	IL17RD,RASAL2,DUSP8,RASGRF2,PRKCD,DAB2IP,ITPR2,PRKCA
R-HSA-2029480	Fcgamma receptor (FCGR) dependent phagocytosis	0.035256553111644	-3.34510386312542	86	4	0.027027027027027	148	10287	2268,3709,1793,5580	FGR,ITPR2,DOCK1,PRKCD
R-HSA-6803204	TP53 Regulates Transcription of Genes Involved in Cytochrome C Release	0.0361083507304212	-3.32123111822182	21	2	0.0135135135135135	148	10287	5366,665	PMAIP1,BNIP3L
R-HSA-112310	Neurotransmitter Release Cycle	0.0367827317798883	-3.30272678904892	51	3	0.0202702702702703	148	10287	8497,18,6812	PPFIA4,ABAT,STXBP1
R-HSA-112315	Transmission across Chemical Synapses	0.0371550944179992	-3.29265438618365	217	7	0.0472972972972973	148	10287	8497,18,5578,785,6812,5924,107	PPFIA4,ABAT,PRKCA,CACNB4,STXBP1,RASGRF2,ADCY1
R-HSA-109582	Hemostasis	0.0382218196713703	-3.2643487308541	632	15	0.101351351351351	148	10287	4072,5768,2268,1793,5777,30845,226,5580,2621,3709,23046,5578,5874,57406,83700	EPCAM,QSOX1,FGR,DOCK1,PTPN6,EHD3,ALDOA,PRKCD,GAS6,ITPR2,KIF21B,PRKCA,RAB27B,ABHD6,JAM3
R-HSA-166663	Initial triggering of complement	0.0393514776799866	-3.2352217526005	22	2	0.0135135135135135	148	10287	10584,720	COLEC10,C4A
R-HSA-1250196	SHC1 events in ERBB2 signaling	0.0393514776799866	-3.2352217526005	22	2	0.0135135135135135	148	10287	5578,5580	PRKCA,PRKCD
R-HSA-2172127	DAP12 interactions	0.041489680486366	-3.18231054564638	371	10	0.0675675675675676	148	10287	54756,57761,9462,1850,5924,5580,107,153090,3709,5578	IL17RD,TRIB3,RASAL2,DUSP8,RASGRF2,PRKCD,ADCY1,DAB2IP,ITPR2,PRKCA
R-HSA-212676	Dopamine Neurotransmitter Release Cycle	0.0427007154297565	-3.15353960409268	23	2	0.0135135135135135	148	10287	8497,6812	PPFIA4,STXBP1
R-HSA-186797	Signaling by PDGF	0.044747838131881	-3.10671214533033	376	10	0.0675675675675676	148	10287	54756,57761,9462,1850,5924,5580,107,153090,3709,5578	IL17RD,TRIB3,RASAL2,DUSP8,RASGRF2,PRKCD,ADCY1,DAB2IP,ITPR2,PRKCA
R-HSA-210500	Glutamate Neurotransmitter Release Cycle	0.0461523846061388	-3.07580664859593	24	2	0.0135135135135135	148	10287	8497,6812	PPFIA4,STXBP1
R-HSA-162582	Signal Transduction	0.0474230464089184	-3.04864695728484	2548	46	0.310810810810811	148	10287	23092,6004,9462,1850,55366,9826,1793,50865,285440,90423,85415,3709,5578,57406,5217,26230,26575,51339,4609,5580,2963,57522,153090,5144,7253,343171,23432,54756,5829,5163,5777,107,55437,23286,7481,93,60485,390442,157,57761,83439,2775,5924,25937,79822,5603	ARHGAP26,RGS16,RASAL2,DUSP8,LGR4,ARHGEF11,DOCK1,HEBP1,CYP4V2,ATP6V1E2,RHPN2,ITPR2,PRKCA,ABHD6,PFN2,TIAM2,RGS17,DACT1,MYC,PRKCD,GTF2F2,SRGAP1,DAB2IP,PDE4D,TSHR,OR2W3,GPR161,IL17RD,PXN,PDK1,PTPN6,ADCY1,STRADB,WWC1,WNT11,ACVR2B,SAV1,OR11H4,GRK3,TRIB3,TCF7L1,GNAO1,RASGRF2,WWTR1,ARHGAP28,MAPK13
R-HSA-76005	Response to elevated platelet cytosolic Ca2+	0.0476089950076997	-3.04473356484749	137	5	0.0337837837837838	148	10287	5768,2621,5874,5578,226	QSOX1,GAS6,RAB27B,PRKCA,ALDOA
R-HSA-425410	Metal ion SLC transporters	0.0497028884821202	-3.00169222921584	25	2	0.0135135135135135	148	10287	30061,64116	SLC40A1,SLC39A8
R-HSA-2029485	Role of phospholipids in phagocytosis	0.0533487113821715	-2.93090545556224	26	2	0.0135135135135135	148	10287	3709,5580	ITPR2,PRKCD
R-HSA-193648	NRAGE signals death through JNK	0.055115572806978	-2.89832297467923	60	3	0.0202702702702703	148	10287	9826,5924,26230	ARHGEF11,RASGRF2,TIAM2
R-HSA-446343	Localization of the PINCH-ILK-PARVIN complex to focal adhesions	0.0563263369920462	-2.87659305584753	4	1	0.00675675675675676	148	10287	5829	PXN
R-HSA-6803544	Ion influx/efflux at host-pathogen interface	0.0563263369920462	-2.87659305584753	4	1	0.00675675675675676	148	10287	475	ATOX1
R-HSA-165158	Activation of AKT2	0.0563263369920462	-2.87659305584753	4	1	0.00675675675675676	148	10287	57761	TRIB3
R-HSA-3858494	Beta-catenin independent WNT signaling	0.0637630382325315	-2.75258159456062	149	5	0.0337837837837838	148	10287	83439,7481,3709,5578,2775	TCF7L1,WNT11,ITPR2,PRKCA,GNAO1
R-HSA-391251	Protein folding	0.064643498992229	-2.73886773578521	105	4	0.027027027027027	148	10287	402,11328,2775,26272	ARL2,FKBP9,GNAO1,FBXO4
R-HSA-2032785	YAP1- and WWTR1 (TAZ)-stimulated gene expression	0.0648241206453251	-2.73607751270418	29	2	0.0135135135135135	148	10287	860,25937	RUNX2,WWTR1
R-HSA-375170	CDO in myogenesis	0.0648241206453251	-2.73607751270418	29	2	0.0135135135135135	148	10287	5608,4756	MAP2K6,NEO1
R-HSA-525793	Myogenesis	0.0648241206453251	-2.73607751270418	29	2	0.0135135135135135	148	10287	5608,4756	MAP2K6,NEO1
R-HSA-5669034	TNFs bind their physiological receptors	0.0688176298453623	-2.67629531911633	30	2	0.0135135135135135	148	10287	9966,608	TNFSF15,TNFRSF17
R-HSA-111448	Activation of NOXA and translocation to mitochondria	0.0699083366152076	-2.6605703719725	5	1	0.00675675675675676	148	10287	5366	PMAIP1
R-HSA-114516	Disinhibition of SNARE formation	0.0699083366152076	-2.6605703719725	5	1	0.00675675675675676	148	10287	5578	PRKCA
R-HSA-8866911	TFAP2 (AP-2) family regulates transcription of cell cycle factors	0.0699083366152076	-2.6605703719725	5	1	0.00675675675675676	148	10287	4609	MYC
R-HSA-426048	Arachidonate production from DAG	0.0699083366152076	-2.6605703719725	5	1	0.00675675675675676	148	10287	57406	ABHD6
R-HSA-70263	Gluconeogenesis	0.077038295230128	-2.56345264011031	32	2	0.0135135135135135	148	10287	2597,226	GAPDH,ALDOA
R-HSA-168638	NOD1/2 Signaling Pathway	0.077038295230128	-2.56345264011031	32	2	0.0135135135135135	148	10287	5603,5608	MAPK13,MAP2K6
R-HSA-376176	Signaling by Robo receptor	0.077038295230128	-2.56345264011031	32	2	0.0135135135135135	148	10287	5217,57522	PFN2,SRGAP1
R-HSA-5690714	CD22 mediated BCR regulation	0.0832961567075684	-2.48535286883809	6	1	0.00675675675675676	148	10287	5777	PTPN6
R-HSA-189483	Heme degradation	0.0832961567075684	-2.48535286883809	6	1	0.00675675675675676	148	10287	645	BLVRB
R-HSA-2173796	SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription	0.085550433946087	-2.4586492062303	34	2	0.0135135135135135	148	10287	4609,25937	MYC,WWTR1
R-HSA-1266738	Developmental Biology	0.0903563376089025	-2.40399411931372	1075	21	0.141891891891892	148	10287	54756,6331,9462,1850,9826,6768,1793,5362,1944,9935,1050,93,5578,785,5217,4756,5924,5608,57522,153090,2051	IL17RD,SCN5A,RASAL2,DUSP8,ARHGEF11,ST14,DOCK1,PLXNA2,EFNA3,MAFB,CEBPA,ACVR2B,PRKCA,CACNB4,PFN2,NEO1,RASGRF2,MAP2K6,SRGAP1,DAB2IP,EPHB6
R-HSA-74752	Signaling by Insulin receptor	0.0930557919713573	-2.37455605203464	322	8	0.0540540540540541	148	10287	54756,57761,9462,1850,5924,55437,90423,153090	IL17RD,TRIB3,RASAL2,DUSP8,RASGRF2,STRADB,ATP6V1E2,DAB2IP
R-HSA-445355	Smooth Muscle Contraction	0.0943309454506498	-2.36094598357139	36	2	0.0135135135135135	148	10287	59,5829	ACTA2,PXN
R-HSA-6806003	Regulation of TP53 Expression and Degradation	0.0943309454506498	-2.36094598357139	36	2	0.0135135135135135	148	10287	6446,639	SGK1,PRDM1
R-HSA-204998	Cell death signalling via NRAGE, NRIF and NADE	0.0962541148923441	-2.34076355459984	76	3	0.0202702702702703	148	10287	9826,5924,26230	ARHGEF11,RASGRF2,TIAM2
R-HSA-442720	CREB phosphorylation through the activation of Adenylate Cyclase	0.0964925548021181	-2.33828942592325	7	1	0.00675675675675676	148	10287	107	ADCY1
R-HSA-174577	Activation of C3 and C5	0.0964925548021181	-2.33828942592325	7	1	0.00675675675675676	148	10287	720	C4A
R-HSA-429593	Inositol transporters	0.0964925548021181	-2.33828942592325	7	1	0.00675675675675676	148	10287	114134	SLC2A13
R-HSA-438064	Post NMDA receptor activation events	0.0988149147603776	-2.31450672650836	37	2	0.0135135135135135	148	10287	5924,107	RASGRF2,ADCY1
R-HSA-1989781	PPARA activates gene expression	0.103558442503107	-2.26761916377247	124	4	0.027027027027027	148	10287	57761,2180,25937,26230	TRIB3,ACSL1,WWTR1,TIAM2
R-HSA-983695	Antigen activates B Cell Receptor (BCR) leading to generation of second messengers	0.107956992906058	-2.2260223449989	39	2	0.0135135135135135	148	10287	3709,5777	ITPR2,PTPN6
R-HSA-111465	Apoptotic cleavage of cellular proteins	0.107956992906058	-2.2260223449989	39	2	0.0135135135135135	148	10287	6304,5580	SATB1,PRKCD
R-HSA-5173214	O-glycosylation of TSR domain-containing proteins	0.107956992906058	-2.2260223449989	39	2	0.0135135135135135	148	10287	145173,9508	B3GLCT,ADAMTS3
R-HSA-444473	Formyl peptide receptors bind formyl peptides and many other ligands	0.109500249534118	-2.21182845087778	8	1	0.00675675675675676	148	10287	50865	HEBP1
R-HSA-2142670	Synthesis of epoxy (EET) and dihydroxyeicosatrienoic acids (DHET)	0.109500249534118	-2.21182845087778	8	1	0.00675675675675676	148	10287	1573	CYP2J2
R-HSA-446388	Regulation of cytoskeletal remodeling and cell spreading by IPP complex components	0.109500249534118	-2.21182845087778	8	1	0.00675675675675676	148	10287	5829	PXN
R-HSA-400206	Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)	0.110507295432305	-2.20267373819188	127	4	0.027027027027027	148	10287	57761,2180,25937,26230	TRIB3,ACSL1,WWTR1,TIAM2
R-HSA-70326	Glucose metabolism	0.1110865454937	-2.19744569233704	81	3	0.0202702702702703	148	10287	2597,226,3099	GAPDH,ALDOA,HK2
R-HSA-195721	Signaling by Wnt	0.111563559687451	-2.19316080845429	336	8	0.0540540540540541	148	10287	83439,55366,51339,2775,4609,7481,3709,5578	TCF7L1,LGR4,DACT1,GNAO1,MYC,WNT11,ITPR2,PRKCA
R-HSA-390471	Association of TriC/CCT with target proteins during biosynthesis	0.112609974315195	-2.18382498535959	40	2	0.0135135135135135	148	10287	11328,26272	FKBP9,FBXO4
R-HSA-1433557	Signaling by SCF-KIT	0.112957978519293	-2.18073940094183	337	8	0.0540540540540541	148	10287	54756,57761,9462,1850,5924,5777,153090,5578	IL17RD,TRIB3,RASAL2,DUSP8,RASGRF2,PTPN6,DAB2IP,PRKCA
R-HSA-442755	Activation of NMDA receptor upon glutamate binding and postsynaptic events	0.117314267021622	-2.14289890223103	41	2	0.0135135135135135	148	10287	5924,107	RASGRF2,ADCY1
R-HSA-373752	Netrin-1 signaling	0.122067457563399	-2.10318145621129	42	2	0.0135135135135135	148	10287	1793,4756	DOCK1,NEO1
R-HSA-5666185	RHO GTPases Activate Rhotekin and Rhophilins	0.122321921205249	-2.10109901109775	9	1	0.00675675675675676	148	10287	85415	RHPN2
R-HSA-1362409	Mitochondrial iron-sulfur cluster biogenesis	0.122321921205249	-2.10109901109775	9	1	0.00675675675675676	148	10287	81894	SLC25A28
R-HSA-159763	Transport of gamma-carboxylated protein precursors from the endoplasmic reticulum to the Golgi apparatus	0.122321921205249	-2.10109901109775	9	1	0.00675675675675676	148	10287	2621	GAS6
R-HSA-111453	BH3-only proteins associate with and inactivate anti-apoptotic BCL-2 members	0.122321921205249	-2.10109901109775	9	1	0.00675675675675676	148	10287	5366	PMAIP1
R-HSA-428543	Inactivation of Cdc42 and Rac	0.122321921205249	-2.10109901109775	9	1	0.00675675675675676	148	10287	57522	SRGAP1
R-HSA-2179392	EGFR Transactivation by Gastrin	0.122321921205249	-2.10109901109775	9	1	0.00675675675675676	148	10287	5578	PRKCA
R-HSA-114608	Platelet degranulation	0.122538252162604	-2.09933203518929	132	4	0.027027027027027	148	10287	5768,2621,5874,226	QSOX1,GAS6,RAB27B,ALDOA
R-HSA-112399	IRS-mediated signalling	0.131464346024678	-2.02901959701967	294	7	0.0472972972972973	148	10287	55437,54756,57761,153090,9462,1850,5924	STRADB,IL17RD,TRIB3,DAB2IP,RASAL2,DUSP8,RASGRF2
R-HSA-917937	Iron uptake and transport	0.13171116694691	-2.02714388303844	44	2	0.0135135135135135	148	10287	90423,30061	ATP6V1E2,SLC40A1
R-HSA-202733	Cell surface interactions at the vascular wall	0.132550120500443	-2.02079443715326	136	4	0.027027027027027	148	10287	4072,2621,83700,5777	EPCAM,GAS6,JAM3,PTPN6
R-HSA-416482	G alpha (12/13) signalling events	0.133204358120582	-2.0158708027881	88	3	0.0202702702702703	148	10287	9826,5924,26230	ARHGEF11,RASGRF2,TIAM2
R-HSA-111367	SLBP independent Processing of Histone Pre-mRNAs	0.134960212278461	-2.00277526784657	10	1	0.00675675675675676	148	10287	134353	LSM11
R-HSA-442380	Zinc influx into cells by the SLC39 gene family	0.134960212278461	-2.00277526784657	10	1	0.00675675675675676	148	10287	64116	SLC39A8
R-HSA-399997	Acetylcholine regulates insulin secretion	0.134960212278461	-2.00277526784657	10	1	0.00675675675675676	148	10287	5578	PRKCA
R-HSA-170660	Adenylate cyclase activating pathway	0.134960212278461	-2.00277526784657	10	1	0.00675675675675676	148	10287	107	ADCY1
R-HSA-2046105	Linoleic acid (LA) metabolism	0.134960212278461	-2.00277526784657	10	1	0.00675675675675676	148	10287	2180	ACSL1
R-HSA-6811555	PI5P Regulates TP53 Acetylation	0.134960212278461	-2.00277526784657	10	1	0.00675675675675676	148	10287	5608	MAP2K6
R-HSA-159740	Gamma-carboxylation of protein precursors	0.134960212278461	-2.00277526784657	10	1	0.00675675675675676	148	10287	2621	GAS6
R-HSA-159782	Removal of aminoterminal propeptides from gamma-carboxylated proteins	0.134960212278461	-2.00277526784657	10	1	0.00675675675675676	148	10287	2621	GAS6
R-HSA-74751	Insulin receptor signalling cascade	0.136502916249626	-1.99140930011922	297	7	0.0472972972972973	148	10287	55437,54756,57761,153090,9462,1850,5924	STRADB,IL17RD,TRIB3,DAB2IP,RASAL2,DUSP8,RASGRF2
R-HSA-166658	Complement cascade	0.136597144119155	-1.99071923895159	45	2	0.0135135135135135	148	10287	10584,720	COLEC10,C4A
R-HSA-2428924	IGF1R signaling cascade	0.138203514660099	-1.97902793627804	298	7	0.0472972972972973	148	10287	55437,54756,57761,153090,9462,1850,5924	STRADB,IL17RD,TRIB3,DAB2IP,RASAL2,DUSP8,RASGRF2
R-HSA-2428928	IRS-related events triggered by IGF1R	0.138203514660099	-1.97902793627804	298	7	0.0472972972972973	148	10287	55437,54756,57761,153090,9462,1850,5924	STRADB,IL17RD,TRIB3,DAB2IP,RASAL2,DUSP8,RASGRF2
R-HSA-2404192	Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R)	0.139914558779426	-1.96672333711096	299	7	0.0472972972972973	148	10287	55437,54756,57761,153090,9462,1850,5924	STRADB,IL17RD,TRIB3,DAB2IP,RASAL2,DUSP8,RASGRF2
R-HSA-2173793	Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer	0.141522933528845	-1.95529350062268	46	2	0.0135135135135135	148	10287	4609,25937	MYC,WWTR1
R-HSA-418346	Platelet homeostasis	0.143120269555153	-1.94406995636287	91	3	0.0202702702702703	148	10287	2268,3709,5777	FGR,ITPR2,PTPN6
R-HSA-381119	Unfolded Protein Response (UPR)	0.146479264633217	-1.92087139888232	92	3	0.0202702702702703	148	10287	7466,1649,2081	WFS1,DDIT3,ERN1
R-HSA-163125	Post-translational modification: synthesis of GPI-anchored proteins	0.146479264633217	-1.92087139888232	92	3	0.0202702702702703	148	10287	51299,8434,2822	NRN1,RECK,GPLD1
R-HSA-5576892	Phase 0 - rapid depolarisation	0.146486400273441	-1.92082268573208	47	2	0.0135135135135135	148	10287	6331,785	SCN5A,CACNB4
R-HSA-381183	ATF6 (ATF6-alpha) activates chaperone genes	0.147417727952786	-1.91448503540878	11	1	0.00675675675675676	148	10287	1649	DDIT3
R-HSA-376172	DSCAM interactions	0.147417727952786	-1.91448503540878	11	1	0.00675675675675676	148	10287	5603	MAPK13
R-HSA-5602498	MyD88 deficiency (TLR2/4)	0.147417727952786	-1.91448503540878	11	1	0.00675675675675676	148	10287	10333	TLR6
R-HSA-5603041	IRAK4 deficiency (TLR2/4)	0.147417727952786	-1.91448503540878	11	1	0.00675675675675676	148	10287	10333	TLR6
R-HSA-189451	Heme biosynthesis	0.147417727952786	-1.91448503540878	11	1	0.00675675675675676	148	10287	7390	UROS
R-HSA-77588	SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs	0.147417727952786	-1.91448503540878	11	1	0.00675675675675676	148	10287	134353	LSM11
R-HSA-159854	Gamma-carboxylation, transport, and amino-terminal cleavage of proteins	0.147417727952786	-1.91448503540878	11	1	0.00675675675675676	148	10287	2621	GAS6
R-HSA-5576891	Cardiac conduction	0.148174570247388	-1.9093641716169	142	4	0.027027027027027	148	10287	6331,3709,785,25937	SCN5A,ITPR2,CACNB4,WWTR1
R-HSA-3928665	EPH-ephrin mediated repulsion of cells	0.151485461848928	-1.88726562003051	48	2	0.0135135135135135	148	10287	2051,1944	EPHB6,EFNA3
R-HSA-168643	Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways	0.151485461848928	-1.88726562003051	48	2	0.0135135135135135	148	10287	5603,5608	MAPK13,MAP2K6
R-HSA-877300	Interferon gamma signaling	0.153274060017163	-1.87552771800811	94	3	0.0202702702702703	148	10287	10612,5777,5580	TRIM3,PTPN6,PRKCD
R-HSA-168249	Innate Immune System	0.157215760689572	-1.8501361451731	1285	23	0.155405405405405	148	10287	54756,5768,9522,9462,1850,1793,720,5777,475,107,90423,3709,10584,5578,10333,57761,2268,5924,5608,5580,226,153090,5603	IL17RD,QSOX1,SCAMP1,RASAL2,DUSP8,DOCK1,C4A,PTPN6,ATOX1,ADCY1,ATP6V1E2,ITPR2,COLEC10,PRKCA,TLR6,TRIB3,FGR,RASGRF2,MAP2K6,PRKCD,ALDOA,DAB2IP,MAPK13
R-HSA-418555	G alpha (s) signalling events	0.158970185129754	-1.83903860925223	146	4	0.027027027027027	148	10287	5144,7253,157,107	PDE4D,TSHR,GRK3,ADCY1
R-HSA-3700989	Transcriptional Regulation by TP53	0.159087155163249	-1.83830308125806	367	8	0.0540540540540541	148	10287	5366,5608,10769,2963,665,6446,8794,639	PMAIP1,MAP2K6,PLK2,GTF2F2,BNIP3L,SGK1,TNFRSF10C,PRDM1
R-HSA-73817	Purine ribonucleoside monophosphate biosynthesis	0.159697036661185	-1.83447677959279	12	1	0.00675675675675676	148	10287	64077	LHPP
R-HSA-6803211	TP53 Regulates Transcription of Death Receptors and Ligands	0.159697036661185	-1.83447677959279	12	1	0.00675675675675676	148	10287	8794	TNFRSF10C
R-HSA-5578768	Physiological factors	0.159697036661185	-1.83447677959279	12	1	0.00675675675675676	148	10287	25937	WWTR1
R-HSA-210990	PECAM1 interactions	0.159697036661185	-1.83447677959279	12	1	0.00675675675675676	148	10287	5777	PTPN6
R-HSA-1433617	Regulation of signaling by NODAL	0.159697036661185	-1.83447677959279	12	1	0.00675675675675676	148	10287	93	ACVR2B
R-HSA-4641265	Repression of WNT target genes	0.159697036661185	-1.83447677959279	12	1	0.00675675675675676	148	10287	83439	TCF7L1
R-HSA-6802949	Signaling by RAS mutants	0.161582295373841	-1.82274069722729	50	2	0.0135135135135135	148	10287	153090,9462	DAB2IP,RASAL2
R-HSA-912526	Interleukin receptor SHC signaling	0.161688874542096	-1.8220813178453	255	6	0.0405405405405405	148	10287	54756,153090,9462,1850,5924,5777	IL17RD,DAB2IP,RASAL2,DUSP8,RASGRF2,PTPN6
R-HSA-193704	p75 NTR receptor-mediated signalling	0.163648960779271	-1.81003162831927	97	3	0.0202702702702703	148	10287	9826,5924,26230	ARHGEF11,RASGRF2,TIAM2
R-HSA-167044	Signalling to RAS	0.163737714490206	-1.80948943329538	256	6	0.0405405405405405	148	10287	54756,5603,153090,9462,1850,5924	IL17RD,MAPK13,DAB2IP,RASAL2,DUSP8,RASGRF2
R-HSA-1227986	Signaling by ERBB2	0.166676155116067	-1.79170254015214	51	2	0.0135135135135135	148	10287	5578,5580	PRKCA,PRKCD
R-HSA-390466	Chaperonin-mediated protein folding	0.170680158871428	-1.76796388984822	99	3	0.0202702702702703	148	10287	11328,2775,26272	FKBP9,GNAO1,FBXO4
R-HSA-1502540	Signaling by Activin	0.171800670581201	-1.761420366173	13	1	0.00675675675675676	148	10287	93	ACVR2B
R-HSA-2029481	FCGR activation	0.171800670581201	-1.761420366173	13	1	0.00675675675675676	148	10287	2268	FGR
R-HSA-5210891	Uptake and function of anthrax toxins	0.171800670581201	-1.761420366173	13	1	0.00675675675675676	148	10287	5608	MAP2K6
R-HSA-171007	p38MAPK events	0.171800670581201	-1.761420366173	13	1	0.00675675675675676	148	10287	5603	MAPK13
R-HSA-112308	Depolarization of the Presynaptic Terminal Triggers the Opening of Calcium Channels	0.171800670581201	-1.761420366173	13	1	0.00675675675675676	148	10287	785	CACNB4
R-HSA-1480926	O2/CO2 exchange in erythrocytes	0.171800670581201	-1.761420366173	13	1	0.00675675675675676	148	10287	51700	CYB5R2
R-HSA-375281	Hormone ligand-binding receptors	0.171800670581201	-1.761420366173	13	1	0.00675675675675676	148	10287	7253	TSHR
R-HSA-71240	Tryptophan catabolism	0.171800670581201	-1.761420366173	13	1	0.00675675675675676	148	10287	8564	KMO
R-HSA-381033	ATF6 (ATF6-alpha) activates chaperones	0.171800670581201	-1.761420366173	13	1	0.00675675675675676	148	10287	1649	DDIT3
R-HSA-1237044	Erythrocytes take up carbon dioxide and release oxygen	0.171800670581201	-1.761420366173	13	1	0.00675675675675676	148	10287	51700	CYB5R2
R-HSA-391160	Signal regulatory protein (SIRP) family interactions	0.171800670581201	-1.761420366173	13	1	0.00675675675675676	148	10287	5777	PTPN6
R-HSA-5607763	CLEC7A (Dectin-1) induces NFAT activation	0.171800670581201	-1.761420366173	13	1	0.00675675675675676	148	10287	3709	ITPR2
R-HSA-451927	Interleukin-2 signaling	0.176263025938791	-1.73577793398498	262	6	0.0405405405405405	148	10287	54756,153090,9462,1850,5924,5777	IL17RD,DAB2IP,RASAL2,DUSP8,RASGRF2,PTPN6
R-HSA-75153	Apoptotic execution  phase	0.176945344064116	-1.73191438469216	53	2	0.0135135135135135	148	10287	6304,5580	SATB1,PRKCD
R-HSA-187687	Signalling to ERKs	0.178388314641293	-1.72379256187112	263	6	0.0405405405405405	148	10287	54756,5603,153090,9462,1850,5924	IL17RD,MAPK13,DAB2IP,RASAL2,DUSP8,RASGRF2
R-HSA-204174	Regulation of pyruvate dehydrogenase (PDH) complex	0.183731126171778	-1.69428186087612	14	1	0.00675675675675676	148	10287	5163	PDK1
R-HSA-418885	DCC mediated attractive signaling	0.183731126171778	-1.69428186087612	14	1	0.00675675675675676	148	10287	1793	DOCK1
R-HSA-877312	Regulation of IFNG signaling	0.183731126171778	-1.69428186087612	14	1	0.00675675675675676	148	10287	5777	PTPN6
R-HSA-881907	Gastrin-CREB signalling pathway via PKC and MAPK	0.188032218588377	-1.6711419553652	443	9	0.0608108108108108	148	10287	54756,9462,1850,5924,5580,153090,3709,5578,57406	IL17RD,RASAL2,DUSP8,RASGRF2,PRKCD,DAB2IP,ITPR2,PRKCA,ABHD6
R-HSA-2672351	Stimuli-sensing channels	0.18862354099305	-1.66800209688467	104	3	0.0202702702702703	148	10287	6446,10110,285335	SGK1,SGK2,SLC9C1
R-HSA-8853659	RET signaling	0.193553112558102	-1.6422033206716	270	6	0.0405405405405405	148	10287	54756,153090,9462,1850,5578,5924	IL17RD,DAB2IP,RASAL2,DUSP8,PRKCA,RASGRF2
R-HSA-2046104	alpha-linolenic (omega3) and linoleic (omega6) acid metabolism	0.195490864648448	-1.63224162878944	15	1	0.00675675675675676	148	10287	2180	ACSL1
R-HSA-2046106	alpha-linolenic acid (ALA) metabolism	0.195490864648448	-1.63224162878944	15	1	0.00675675675675676	148	10287	2180	ACSL1
R-HSA-4419969	Depolymerisation of the Nuclear Lamina	0.195490864648448	-1.63224162878944	15	1	0.00675675675675676	148	10287	5578	PRKCA
R-HSA-3371568	Attenuation phase	0.195490864648448	-1.63224162878944	15	1	0.00675675675675676	148	10287	3306	HSPA2
R-HSA-211935	Fatty acids	0.195490864648448	-1.63224162878944	15	1	0.00675675675675676	148	10287	1573	CYP2J2
R-HSA-170670	Adenylate cyclase inhibitory pathway	0.195490864648448	-1.63224162878944	15	1	0.00675675675675676	148	10287	107	ADCY1
R-HSA-399955	SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion	0.195490864648448	-1.63224162878944	15	1	0.00675675675675676	148	10287	5362	PLXNA2
R-HSA-997269	Inhibition of adenylate cyclase pathway	0.195490864648448	-1.63224162878944	15	1	0.00675675675675676	148	10287	107	ADCY1
R-HSA-5099900	WNT5A-dependent internalization of FZD4	0.195490864648448	-1.63224162878944	15	1	0.00675675675675676	148	10287	5578	PRKCA
R-HSA-512988	Interleukin-3, 5 and GM-CSF signaling	0.195759287488895	-1.63086949957188	271	6	0.0405405405405405	148	10287	54756,153090,9462,1850,5924,5777	IL17RD,DAB2IP,RASAL2,DUSP8,RASGRF2,PTPN6
R-HSA-425366	Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds	0.19593435285618	-1.62997561026192	106	3	0.0202702702702703	148	10287	30061,114134,64116	SLC40A1,SLC2A13,SLC39A8
R-HSA-381070	IRE1alpha activates chaperones	0.203011083664741	-1.59449470209714	58	2	0.0135135135135135	148	10287	7466,2081	WFS1,ERN1
R-HSA-375165	NCAM signaling for neurite out-growth	0.206931906825895	-1.57536549236543	276	6	0.0405405405405405	148	10287	54756,153090,9462,1850,785,5924	IL17RD,DAB2IP,RASAL2,DUSP8,CACNB4,RASGRF2
R-HSA-399956	CRMPs in Sema3A signaling	0.207082312468491	-1.57463891998118	16	1	0.00675675675675676	148	10287	5362	PLXNA2
R-HSA-5686938	Regulation of TLR by endogenous ligand	0.207082312468491	-1.57463891998118	16	1	0.00675675675675676	148	10287	10333	TLR6
R-HSA-163615	PKA activation	0.207082312468491	-1.57463891998118	16	1	0.00675675675675676	148	10287	107	ADCY1
R-HSA-446353	Cell-extracellular matrix interactions	0.207082312468491	-1.57463891998118	16	1	0.00675675675675676	148	10287	5829	PXN
R-HSA-399954	Sema3A PAK dependent Axon repulsion	0.207082312468491	-1.57463891998118	16	1	0.00675675675675676	148	10287	5362	PLXNA2
R-HSA-111931	PKA-mediated phosphorylation of CREB	0.218507861860467	-1.52093328403903	17	1	0.00675675675675676	148	10287	107	ADCY1
R-HSA-435354	Zinc transporters	0.218507861860467	-1.52093328403903	17	1	0.00675675675675676	148	10287	64116	SLC39A8
R-HSA-164378	PKA activation in glucagon signalling	0.218507861860467	-1.52093328403903	17	1	0.00675675675675676	148	10287	107	ADCY1
R-HSA-139853	Elevation of cytosolic Ca2+ levels	0.218507861860467	-1.52093328403903	17	1	0.00675675675675676	148	10287	3709	ITPR2
R-HSA-416993	Trafficking of GluR2-containing AMPA receptors	0.218507861860467	-1.52093328403903	17	1	0.00675675675675676	148	10287	5578	PRKCA
R-HSA-6802952	Signaling by BRAF and RAF fusions	0.218854005985207	-1.5193504108054	61	2	0.0135135135135135	148	10287	80853,57670	KDM7A,KIAA1549
R-HSA-197264	Nicotinamide salvaging	0.229769871248731	-1.47067703074116	18	1	0.00675675675675676	148	10287	83666	PARP9
R-HSA-8873719	RAB geranylgeranylation	0.234799670185008	-1.44902259569269	64	2	0.0135135135135135	148	10287	23682,5874	RAB38,RAB27B
R-HSA-372790	Signaling by GPCR	0.236938905957695	-1.4399529518474	1299	22	0.148648648648649	148	10287	54756,6004,9462,1850,9826,50865,107,7481,3709,5578,390442,57406,157,26230,26575,2775,5924,5580,153090,5144,7253,343171	IL17RD,RGS16,RASAL2,DUSP8,ARHGEF11,HEBP1,ADCY1,WNT11,ITPR2,PRKCA,OR11H4,ABHD6,GRK3,TIAM2,RGS17,GNAO1,RASGRF2,PRKCD,DAB2IP,PDE4D,TSHR,OR2W3
R-HSA-5683057	MAPK family signaling cascades	0.239367054238385	-1.42975711338036	290	6	0.0405405405405405	148	10287	54756,153090,9462,1850,5924,4609	IL17RD,DAB2IP,RASAL2,DUSP8,RASGRF2,MYC
R-HSA-416700	Other semaphorin interactions	0.240870665778696	-1.42349514606307	19	1	0.00675675675675676	148	10287	5362	PLXNA2
R-HSA-8851708	Signaling by FGFR2 IIIa TM	0.240870665778696	-1.42349514606307	19	1	0.00675675675675676	148	10287	2963	GTF2F2
R-HSA-442982	Ras activation uopn Ca2+ infux through NMDA receptor	0.240870665778696	-1.42349514606307	19	1	0.00675675675675676	148	10287	5924	RASGRF2
R-HSA-3928664	Ephrin signaling	0.240870665778696	-1.42349514606307	19	1	0.00675675675675676	148	10287	2051	EPHB6
R-HSA-168256	Immune System	0.247356048051435	-1.39692649021687	2101	34	0.22972972972973	148	10287	91694,9522,9462,1850,1793,720,26272,90423,3709,10584,55008,5578,1780,4609,5580,8139,10612,153090,64219,5768,54756,26249,5777,475,107,10333,57761,2268,5608,5924,226,5603,9966,608	LONRF1,SCAMP1,RASAL2,DUSP8,DOCK1,C4A,FBXO4,ATP6V1E2,ITPR2,COLEC10,HERC6,PRKCA,DYNC1I1,MYC,PRKCD,GAN,TRIM3,DAB2IP,PJA1,QSOX1,IL17RD,KLHL3,PTPN6,ATOX1,ADCY1,TLR6,TRIB3,FGR,MAP2K6,RASGRF2,ALDOA,MAPK13,TNFSF15,TNFRSF17
R-HSA-450302	activated TAK1 mediates p38 MAPK activation	0.251812537761357	-1.37907036607235	20	1	0.00675675675675676	148	10287	5608	MAP2K6
R-HSA-3000170	Syndecan interactions	0.251812537761357	-1.37907036607235	20	1	0.00675675675675676	148	10287	5578	PRKCA
R-HSA-373755	Semaphorin interactions	0.25615663528857	-1.36196616501453	68	2	0.0135135135135135	148	10287	9826,5362	ARHGEF11,PLXNA2
R-HSA-211897	Cytochrome P450 - arranged by substrate type	0.25615663528857	-1.36196616501453	68	2	0.0135135135135135	148	10287	1573,285440	CYP2J2,CYP4V2
R-HSA-388841	Costimulation by the CD28 family	0.261504591639872	-1.34130343677903	69	2	0.0135135135135135	148	10287	57761,5777	TRIB3,PTPN6
R-HSA-212436	Generic Transcription Pathway	0.261651530096143	-1.34074169830736	865	15	0.101351351351351	148	10287	79047,860,90874,5366,5608,10769,4609,25937,2963,665,6446,639,8794,148156,284252	KCTD15,RUNX2,ZNF697,PMAIP1,MAP2K6,PLK2,MYC,WWTR1,GTF2F2,BNIP3L,SGK1,PRDM1,TNFRSF10C,ZNF558,KCTD1
R-HSA-6804115	TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain	0.262597747111541	-1.33713189631422	21	1	0.00675675675675676	148	10287	10769	PLK2
R-HSA-1181150	Signaling by NODAL	0.262597747111541	-1.33713189631422	21	1	0.00675675675675676	148	10287	93	ACVR2B
R-HSA-5658442	Regulation of RAS by GAPs	0.266853656345288	-1.32105487442126	70	2	0.0135135135135135	148	10287	153090,9462	DAB2IP,RASAL2
R-HSA-1650814	Collagen biosynthesis and modifying enzymes	0.266853656345288	-1.32105487442126	70	2	0.0135135135135135	148	10287	5033,9508	P4HA1,ADAMTS3
R-HSA-194315	Signaling by Rho GTPases	0.272431078544568	-1.30036961964142	427	8	0.0540540540540541	148	10287	23092,9826,5924,57522,85415,79822,5217,26230	ARHGAP26,ARHGEF11,RASGRF2,SRGAP1,RHPN2,ARHGAP28,PFN2,TIAM2
R-HSA-389357	CD28 dependent PI3K/Akt signaling	0.273228521844277	-1.29744675759754	22	1	0.00675675675675676	148	10287	57761	TRIB3
R-HSA-4641263	Regulation of FZD by ubiquitination	0.273228521844277	-1.29744675759754	22	1	0.00675675675675676	148	10287	55366	LGR4
R-HSA-180336	SHC1 events in EGFR signaling	0.277453234920952	-1.28210288280459	245	5	0.0337837837837838	148	10287	54756,153090,9462,1850,5924	IL17RD,DAB2IP,RASAL2,DUSP8,RASGRF2
R-HSA-5673001	RAF/MAP kinase cascade	0.277453234920952	-1.28210288280459	245	5	0.0337837837837838	148	10287	54756,153090,9462,1850,5924	IL17RD,DAB2IP,RASAL2,DUSP8,RASGRF2
R-HSA-179812	GRB2 events in EGFR signaling	0.277453234920952	-1.28210288280459	245	5	0.0337837837837838	148	10287	54756,153090,9462,1850,5924	IL17RD,DAB2IP,RASAL2,DUSP8,RASGRF2
R-HSA-112412	SOS-mediated signalling	0.277453234920952	-1.28210288280459	245	5	0.0337837837837838	148	10287	54756,153090,9462,1850,5924	IL17RD,DAB2IP,RASAL2,DUSP8,RASGRF2
R-HSA-389948	PD-1 signaling	0.283707058501659	-1.25981305731589	23	1	0.00675675675675676	148	10287	5777	PTPN6
R-HSA-389977	Post-chaperonin tubulin folding pathway	0.283707058501659	-1.25981305731589	23	1	0.00675675675675676	148	10287	402	ARL2
R-HSA-2453902	The canonical retinoid cycle in rods (twilight vision)	0.283707058501659	-1.25981305731589	23	1	0.00675675675675676	148	10287	285440	CYP4V2
R-HSA-3371571	HSF1-dependent transactivation	0.283707058501659	-1.25981305731589	23	1	0.00675675675675676	148	10287	3306	HSPA2
R-HSA-112409	RAF-independent MAPK1/3 activation	0.283707058501659	-1.25981305731589	23	1	0.00675675675675676	148	10287	1850	DUSP8
R-HSA-2454202	Fc epsilon receptor (FCERI) signaling	0.288217418393121	-1.2440401586826	372	7	0.0472972972972973	148	10287	54756,57761,153090,3709,9462,1850,5924	IL17RD,TRIB3,DAB2IP,ITPR2,RASAL2,DUSP8,RASGRF2
R-HSA-170984	ARMS-mediated activation	0.288580625332386	-1.24278076818632	249	5	0.0337837837837838	148	10287	54756,153090,9462,1850,5924	IL17RD,DAB2IP,RASAL2,DUSP8,RASGRF2
R-HSA-187706	Signalling to p38 via RIT and RIN	0.288580625332386	-1.24278076818632	249	5	0.0337837837837838	148	10287	54756,153090,9462,1850,5924	IL17RD,DAB2IP,RASAL2,DUSP8,RASGRF2
R-HSA-983169	Class I MHC mediated antigen processing & presentation	0.29049256039631	-1.23617731266936	373	7	0.0472972972972973	148	10287	91694,64219,55008,26249,10333,26272,8139	LONRF1,PJA1,HERC6,KLHL3,TLR6,FBXO4,GAN
R-HSA-983168	Antigen processing: Ubiquitination & Proteasome degradation	0.290600457481236	-1.23580595358279	311	6	0.0405405405405405	148	10287	91694,64219,55008,26249,26272,8139	LONRF1,PJA1,HERC6,KLHL3,FBXO4,GAN
R-HSA-170968	Frs2-mediated activation	0.291375808538916	-1.23314140672173	250	5	0.0337837837837838	148	10287	54756,153090,9462,1850,5924	IL17RD,DAB2IP,RASAL2,DUSP8,RASGRF2
R-HSA-5602358	Diseases associated with the TLR signaling cascade	0.294035522579549	-1.22405469384171	24	1	0.00675675675675676	148	10287	10333	TLR6
R-HSA-416572	Sema4D induced cell migration and growth-cone collapse	0.294035522579549	-1.22405469384171	24	1	0.00675675675675676	148	10287	9826	ARHGEF11
R-HSA-171052	LDL-mediated lipid transport	0.294035522579549	-1.22405469384171	24	1	0.00675675675675676	148	10287	57552	NCEH1
R-HSA-5260271	Diseases of Immune System	0.294035522579549	-1.22405469384171	24	1	0.00675675675675676	148	10287	10333	TLR6
R-HSA-201451	Signaling by BMP	0.294035522579549	-1.22405469384171	24	1	0.00675675675675676	148	10287	93	ACVR2B
R-HSA-5684996	MAPK1/MAPK3 signaling	0.294175970564236	-1.22357715136254	251	5	0.0337837837837838	148	10287	54756,153090,9462,1850,5924	IL17RD,DAB2IP,RASAL2,DUSP8,RASGRF2
R-HSA-169893	Prolonged ERK activation events	0.296980934529473	-1.21408733574339	252	5	0.0337837837837838	148	10287	54756,153090,9462,1850,5924	IL17RD,DAB2IP,RASAL2,DUSP8,RASGRF2
R-HSA-1500931	Cell-Cell communication	0.299562924991054	-1.2054307833575	133	3	0.0202702702702703	148	10287	5603,5829,5777	MAPK13,PXN,PTPN6
R-HSA-2586552	Signaling by Leptin	0.299790524062091	-1.20467130134455	253	5	0.0337837837837838	148	10287	54756,153090,9462,1850,5924	IL17RD,DAB2IP,RASAL2,DUSP8,RASGRF2
R-HSA-211981	Xenobiotics	0.304216049002956	-1.19001714248497	25	1	0.00675675675675676	148	10287	1573	CYP2J2
R-HSA-167242	Abortive elongation of HIV-1 transcript in the absence of Tat	0.304216049002956	-1.19001714248497	25	1	0.00675675675675676	148	10287	2963	GTF2F2
R-HSA-982772	Growth hormone receptor signaling	0.304216049002956	-1.19001714248497	25	1	0.00675675675675676	148	10287	5777	PTPN6
R-HSA-170834	Signaling by TGF-beta Receptor Complex	0.304237063449951	-1.18994806749276	77	2	0.0135135135135135	148	10287	4609,25937	MYC,WWTR1
R-HSA-912694	Regulation of IFNA signaling	0.314250742505381	-1.15756406872895	26	1	0.00675675675675676	148	10287	5777	PTPN6
R-HSA-1971475	A tetrasaccharide linker sequence is required for GAG synthesis	0.314250742505381	-1.15756406872895	26	1	0.00675675675675676	148	10287	11285	B4GALT7
R-HSA-3238698	WNT ligand biogenesis and trafficking	0.314250742505381	-1.15756406872895	26	1	0.00675675675675676	148	10287	7481	WNT11
R-HSA-109704	PI3K Cascade	0.314868697878451	-1.15559955918707	79	2	0.0135135135135135	148	10287	55437,57761	STRADB,TRIB3
R-HSA-180024	DARPP-32 events	0.32414167809896	-1.1265745806848	27	1	0.00675675675675676	148	10287	5144	PDE4D
R-HSA-977606	Regulation of Complement cascade	0.32414167809896	-1.1265745806848	27	1	0.00675675675675676	148	10287	720	C4A
R-HSA-77075	RNA Pol II CTD phosphorylation and interaction with CE	0.32414167809896	-1.1265745806848	27	1	0.00675675675675676	148	10287	2963	GTF2F2
R-HSA-400685	Sema4D in semaphorin signaling	0.32414167809896	-1.1265745806848	27	1	0.00675675675675676	148	10287	9826	ARHGEF11
R-HSA-380994	ATF4 activates genes	0.32414167809896	-1.1265745806848	27	1	0.00675675675675676	148	10287	1649	DDIT3
R-HSA-77387	Insulin receptor recycling	0.32414167809896	-1.1265745806848	27	1	0.00675675675675676	148	10287	90423	ATP6V1E2
R-HSA-167160	RNA Pol II CTD phosphorylation and interaction with CE during HIV infection	0.32414167809896	-1.1265745806848	27	1	0.00675675675675676	148	10287	2963	GTF2F2
R-HSA-388396	GPCR downstream signaling	0.326050632875621	-1.12070259410625	974	16	0.108108108108108	148	10287	6004,9826,50865,107,3709,5578,390442,57406,157,26230,26575,5924,5580,5144,343171,7253	RGS16,ARHGEF11,HEBP1,ADCY1,ITPR2,PRKCA,OR11H4,ABHD6,GRK3,TIAM2,RGS17,RASGRF2,PRKCD,PDE4D,OR2W3,TSHR
R-HSA-2871796	FCERI mediated MAPK activation	0.333803007554894	-1.09720425774438	265	5	0.0337837837837838	148	10287	54756,153090,9462,1850,5924	IL17RD,DAB2IP,RASAL2,DUSP8,RASGRF2
R-HSA-5576893	Phase 2 - plateau phase	0.333890901458417	-1.09694098170474	28	1	0.00675675675675676	148	10287	785	CACNB4
R-HSA-70268	Pyruvate metabolism	0.333890901458417	-1.09694098170474	28	1	0.00675675675675676	148	10287	5163	PDK1
R-HSA-264876	Insulin processing	0.333890901458417	-1.09694098170474	28	1	0.00675675675675676	148	10287	3800	KIF5C
R-HSA-6803529	FGFR2 alternative splicing	0.333890901458417	-1.09694098170474	28	1	0.00675675675675676	148	10287	2963	GTF2F2
R-HSA-211976	Endogenous sterols	0.333890901458417	-1.09694098170474	28	1	0.00675675675675676	148	10287	285440	CYP4V2
R-HSA-380972	Energy dependent regulation of mTOR by LKB1-AMPK	0.333890901458417	-1.09694098170474	28	1	0.00675675675675676	148	10287	55437	STRADB
R-HSA-6811436	COPI-independent Golgi-to-ER retrograde traffic	0.333890901458417	-1.09694098170474	28	1	0.00675675675675676	148	10287	1780	DYNC1I1
R-HSA-75876	Synthesis of very long-chain fatty acyl-CoAs	0.333890901458417	-1.09694098170474	28	1	0.00675675675675676	148	10287	2180	ACSL1
R-HSA-1482839	Acyl chain remodelling of PE	0.343500429336808	-1.0685669174317	29	1	0.00675675675675676	148	10287	63874	ABHD4
R-HSA-5218920	VEGFR2 mediated vascular permeability	0.343500429336808	-1.0685669174317	29	1	0.00675675675675676	148	10287	57761	TRIB3
R-HSA-72086	mRNA Capping	0.343500429336808	-1.0685669174317	29	1	0.00675675675675676	148	10287	2963	GTF2F2
R-HSA-196807	Nicotinate metabolism	0.343500429336808	-1.0685669174317	29	1	0.00675675675675676	148	10287	83666	PARP9
R-HSA-442742	CREB phosphorylation through the activation of Ras	0.343500429336808	-1.0685669174317	29	1	0.00675675675675676	148	10287	5924	RASGRF2
R-HSA-202040	G-protein activation	0.343500429336808	-1.0685669174317	29	1	0.00675675675675676	148	10287	2775	GNAO1
R-HSA-112314	Neurotransmitter Receptor Binding And Downstream Transmission In The  Postsynaptic Cell	0.350864387042677	-1.04735549187496	146	3	0.0202702702702703	148	10287	5578,5924,107	PRKCA,RASGRF2,ADCY1
R-HSA-2871809	FCERI mediated Ca+2 mobilization	0.352972250008772	-1.04136583701208	30	1	0.00675675675675676	148	10287	3709	ITPR2
R-HSA-917977	Transferrin endocytosis and recycling	0.352972250008772	-1.04136583701208	30	1	0.00675675675675676	148	10287	90423	ATP6V1E2
R-HSA-381042	PERK regulates gene expression	0.352972250008772	-1.04136583701208	30	1	0.00675675675675676	148	10287	1649	DDIT3
R-HSA-445095	Interaction between L1 and Ankyrins	0.352972250008772	-1.04136583701208	30	1	0.00675675675675676	148	10287	6331	SCN5A
R-HSA-983712	Ion channel transport	0.354296655641115	-1.0376207064973	209	4	0.027027027027027	148	10287	90423,6446,10110,285335	ATP6V1E2,SGK1,SGK2,SLC9C1
R-HSA-6804758	Regulation of TP53 Activity through Acetylation	0.362308323614604	-1.01525970697404	31	1	0.00675675675675676	148	10287	5608	MAP2K6
R-HSA-5339562	Uptake and actions of bacterial toxins	0.362308323614604	-1.01525970697404	31	1	0.00675675675675676	148	10287	5608	MAP2K6
R-HSA-75067	Processing of Capped Intronless Pre-mRNA	0.362308323614604	-1.01525970697404	31	1	0.00675675675675676	148	10287	134353	LSM11
R-HSA-418360	Platelet calcium homeostasis	0.362308323614604	-1.01525970697404	31	1	0.00675675675675676	148	10287	3709	ITPR2
R-HSA-114452	Activation of BH3-only proteins	0.362308323614604	-1.01525970697404	31	1	0.00675675675675676	148	10287	5366	PMAIP1
R-HSA-8876198	RAB GEFs exchange GTP for GDP on RABs	0.367369889826348	-1.00138606430551	89	2	0.0135135135135135	148	10287	23682,5874	RAB38,RAB27B
R-HSA-399719	Trafficking of AMPA receptors	0.371510582601053	-0.990177929089929	32	1	0.00675675675675676	148	10287	5578	PRKCA
R-HSA-399721	Glutamate Binding, Activation of AMPA Receptors and Synaptic Plasticity	0.371510582601053	-0.990177929089929	32	1	0.00675675675675676	148	10287	5578	PRKCA
R-HSA-201722	Formation of the beta-catenin:TCF transactivating complex	0.377697761476872	-0.973660976003894	91	2	0.0135135135135135	148	10287	83439,4609	TCF7L1,MYC
R-HSA-450531	Regulation of mRNA stability by proteins that bind AU-rich elements	0.377697761476872	-0.973660976003894	91	2	0.0135135135135135	148	10287	5578,5580	PRKCA,PRKCD
R-HSA-1839126	FGFR2 mutant receptor activation	0.380580932071039	-0.966056425030821	33	1	0.00675675675675676	148	10287	2963	GTF2F2
R-HSA-1222556	ROS, RNS production in phagocytes	0.380580932071039	-0.966056425030821	33	1	0.00675675675675676	148	10287	90423	ATP6V1E2
R-HSA-163359	Glucagon signaling in metabolic regulation	0.380580932071039	-0.966056425030821	33	1	0.00675675675675676	148	10287	107	ADCY1
R-HSA-389356	CD28 co-stimulation	0.380580932071039	-0.966056425030821	33	1	0.00675675675675676	148	10287	57761	TRIB3
R-HSA-1474290	Collagen formation	0.387956211427967	-0.946862802872126	93	2	0.0135135135135135	148	10287	5033,9508	P4HA1,ADAMTS3
R-HSA-73847	Purine metabolism	0.389521250191143	-0.942836857544288	34	1	0.00675675675675676	148	10287	64077	LHPP
R-HSA-390522	Striated Muscle Contraction	0.389521250191143	-0.942836857544288	34	1	0.00675675675675676	148	10287	29767	TMOD2
R-HSA-3928663	EPHA-mediated growth cone collapse	0.389521250191143	-0.942836857544288	34	1	0.00675675675675676	148	10287	1944	EFNA3
R-HSA-5693568	Resolution of D-loop Structures through Holliday Junction Intermediates	0.389521250191143	-0.942836857544288	34	1	0.00675675675675676	148	10287	79008	SLX1B
R-HSA-983231	Factors involved in megakaryocyte development and platelet production	0.390102673664094	-0.941345308701438	156	3	0.0202702702702703	148	10287	23046,1793,30845	KIF21B,DOCK1,EHD3
R-HSA-166058	MyD88:Mal cascade initiated on plasma membrane	0.398140779669805	-0.920949618477751	95	2	0.0135135135135135	148	10287	10333,5608	TLR6,MAP2K6
R-HSA-168188	Toll Like Receptor TLR6:TLR2 Cascade	0.398140779669805	-0.920949618477751	95	2	0.0135135135135135	148	10287	10333,5608	TLR6,MAP2K6
R-HSA-181438	Toll Like Receptor 2 (TLR2) Cascade	0.398140779669805	-0.920949618477751	95	2	0.0135135135135135	148	10287	10333,5608	TLR6,MAP2K6
R-HSA-2682334	EPH-Ephrin signaling	0.398140779669805	-0.920949618477751	95	2	0.0135135135135135	148	10287	2051,1944	EPHB6,EFNA3
R-HSA-168179	Toll Like Receptor TLR1:TLR2 Cascade	0.398140779669805	-0.920949618477751	95	2	0.0135135135135135	148	10287	10333,5608	TLR6,MAP2K6
R-HSA-113418	Formation of the Early Elongation Complex	0.398333388590449	-0.920465964563852	35	1	0.00675675675675676	148	10287	2963	GTF2F2
R-HSA-6804757	Regulation of TP53 Degradation	0.398333388590449	-0.920465964563852	35	1	0.00675675675675676	148	10287	6446	SGK1
R-HSA-5693537	Resolution of D-Loop Structures	0.398333388590449	-0.920465964563852	35	1	0.00675675675675676	148	10287	79008	SLX1B
R-HSA-2514859	Inactivation, recovery and regulation of the phototransduction cascade	0.398333388590449	-0.920465964563852	35	1	0.00675675675675676	148	10287	5578	PRKCA
R-HSA-167158	Formation of the HIV-1 Early Elongation Complex	0.398333388590449	-0.920465964563852	35	1	0.00675675675675676	148	10287	2963	GTF2F2
R-HSA-4086400	PCP/CE pathway	0.403204048915608	-0.908312520322006	96	2	0.0135135135135135	148	10287	7481,5578	WNT11,PRKCA
R-HSA-1280215	Cytokine Signaling in Immune system	0.405199895700981	-0.903374764008971	756	12	0.0810810810810811	148	10287	54756,9462,1850,5608,5924,5777,4609,5580,10612,9966,153090,608	IL17RD,RASAL2,DUSP8,MAP2K6,RASGRF2,PTPN6,MYC,PRKCD,TRIM3,TNFSF15,DAB2IP,TNFRSF17
R-HSA-2514856	The phototransduction cascade	0.407019172679485	-0.898894987328455	36	1	0.00675675675675676	148	10287	5578	PRKCA
R-HSA-5633007	Regulation of TP53 Activity	0.413384790074157	-0.883376424684768	162	3	0.0202702702702703	148	10287	6446,639,5608	SGK1,PRDM1,MAP2K6
R-HSA-419037	NCAM1 interactions	0.415580402066186	-0.878079176628833	37	1	0.00675675675675676	148	10287	785	CACNB4
R-HSA-5083635	Defective B3GALTL causes Peters-plus syndrome (PpS)	0.415580402066186	-0.878079176628833	37	1	0.00675675675675676	148	10287	9508	ADAMTS3
R-HSA-1474244	Extracellular matrix organization	0.422594341666833	-0.861342563225283	296	5	0.0337837837837838	148	10287	5033,5578,9508,83700,726	P4HA1,PRKCA,ADAMTS3,JAM3,CAPN5
R-HSA-167238	Pausing and recovery of Tat-mediated HIV elongation	0.424018850902445	-0.857977365062904	38	1	0.00675675675675676	148	10287	2963	GTF2F2
R-HSA-3299685	Detoxification of Reactive Oxygen Species	0.424018850902445	-0.857977365062904	38	1	0.00675675675675676	148	10287	475	ATOX1
R-HSA-167243	Tat-mediated HIV elongation arrest and recovery	0.424018850902445	-0.857977365062904	38	1	0.00675675675675676	148	10287	2963	GTF2F2
R-HSA-2187338	Visual phototransduction	0.4282111284496	-0.848138914258141	101	2	0.0135135135135135	148	10287	5578,285440	PRKCA,CYP4V2
R-HSA-5607764	CLEC7A (Dectin-1) signaling	0.4282111284496	-0.848138914258141	101	2	0.0135135135135135	148	10287	3709,5580	ITPR2,PRKCD
R-HSA-5610787	Hedgehog 'off' state	0.4282111284496	-0.848138914258141	101	2	0.0135135135135135	148	10287	23432,107	GPR161,ADCY1
R-HSA-6783310	Fanconi Anemia Pathway	0.432336268210727	-0.838551594897183	39	1	0.00675675675675676	148	10287	79008	SLX1B
R-HSA-5674135	MAP2K and MAPK activation	0.432336268210727	-0.838551594897183	39	1	0.00675675675675676	148	10287	54756	IL17RD
R-HSA-163841	Gamma carboxylation, hypusine formation and arylsulfatase activation	0.432336268210727	-0.838551594897183	39	1	0.00675675675675676	148	10287	2621	GAS6
R-HSA-165159	mTOR signalling	0.432336268210727	-0.838551594897183	39	1	0.00675675675675676	148	10287	55437	STRADB
R-HSA-167287	HIV elongation arrest and recovery	0.440534378309753	-0.819766792815176	40	1	0.00675675675675676	148	10287	2963	GTF2F2
R-HSA-5675221	Negative regulation of MAPK pathway	0.440534378309753	-0.819766792815176	40	1	0.00675675675675676	148	10287	1850	DUSP8
R-HSA-977444	GABA B receptor activation	0.440534378309753	-0.819766792815176	40	1	0.00675675675675676	148	10287	107	ADCY1
R-HSA-167290	Pausing and recovery of HIV elongation	0.440534378309753	-0.819766792815176	40	1	0.00675675675675676	148	10287	2963	GTF2F2
R-HSA-991365	Activation of GABAB receptors	0.440534378309753	-0.819766792815176	40	1	0.00675675675675676	148	10287	107	ADCY1
R-HSA-109703	PKB-mediated events	0.440534378309753	-0.819766792815176	40	1	0.00675675675675676	148	10287	55437	STRADB
R-HSA-5663202	Diseases of signal transduction	0.44195011744865	-0.816558259724224	370	6	0.0405405405405405	148	10287	80853,153090,9462,4609,57670,2963	KDM7A,DAB2IP,RASAL2,MYC,KIAA1549,GTF2F2
R-HSA-5668541	TNFR2 non-canonical NF-kB pathway	0.442952462768881	-0.814292822214322	104	2	0.0135135135135135	148	10287	9966,608	TNFSF15,TNFRSF17
R-HSA-5620924	Intraflagellar transport	0.44861488108901	-0.80159048515685	41	1	0.00675675675675676	148	10287	28981	IFT81
R-HSA-201681	TCF dependent signaling in response to WNT	0.448629336686471	-0.801558262943152	238	4	0.027027027027027	148	10287	83439,55366,51339,4609	TCF7L1,LGR4,DACT1,MYC
R-HSA-109581	Apoptosis	0.451542291559149	-0.795086241499252	172	3	0.0202702702702703	148	10287	5366,6304,5580	PMAIP1,SATB1,PRKCD
R-HSA-983189	Kinesins	0.456579452398719	-0.783992547215897	42	1	0.00675675675675676	148	10287	23046	KIF21B
R-HSA-3928662	EPHB-mediated forward signaling	0.456579452398719	-0.783992547215897	42	1	0.00675675675675676	148	10287	2051	EPHB6
R-HSA-381676	Glucagon-like Peptide-1 (GLP1) regulates insulin secretion	0.456579452398719	-0.783992547215897	42	1	0.00675675675675676	148	10287	3709	ITPR2
R-HSA-5357801	Programmed Cell Death	0.462799340643465	-0.770461708375244	175	3	0.0202702702702703	148	10287	5366,6304,5580	PMAIP1,SATB1,PRKCD
R-HSA-168325	Viral Messenger RNA Synthesis	0.464429744346816	-0.766944982228363	43	1	0.00675675675675676	148	10287	2963	GTF2F2
R-HSA-6814122	Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding	0.464429744346816	-0.766944982228363	43	1	0.00675675675675676	148	10287	2775	GNAO1
R-HSA-3769402	Deactivation of the beta-catenin transactivating complex	0.464429744346816	-0.766944982228363	43	1	0.00675675675675676	148	10287	83439	TCF7L1
R-HSA-5655253	Signaling by FGFR2 in disease	0.464429744346816	-0.766944982228363	43	1	0.00675675675675676	148	10287	2963	GTF2F2
R-HSA-5362517	Signaling by Retinoic Acid	0.464429744346816	-0.766944982228363	43	1	0.00675675675675676	148	10287	5163	PDK1
R-HSA-432040	Vasopressin regulates renal water homeostasis via Aquaporins	0.464429744346816	-0.766944982228363	43	1	0.00675675675675676	148	10287	107	ADCY1
R-HSA-211945	Phase 1 - Functionalization of compounds	0.467050704363853	-0.761317452552109	109	2	0.0135135135135135	148	10287	1573,285440	CYP2J2,CYP4V2
R-HSA-8856688	Golgi-to-ER retrograde transport	0.471796854286961	-0.751206779502258	110	2	0.0135135135135135	148	10287	23046,1780	KIF21B,DYNC1I1
R-HSA-6788656	Histidine, lysine, phenylalanine, tyrosine, proline and tryptophan catabolism	0.472167385690072	-0.750421725563881	44	1	0.00675675675675676	148	10287	8564	KMO
R-HSA-109606	Intrinsic Pathway for Apoptosis	0.472167385690072	-0.750421725563881	44	1	0.00675675675675676	148	10287	5366	PMAIP1
R-HSA-3000171	Non-integrin membrane-ECM interactions	0.479793982077955	-0.734398471218863	45	1	0.00675675675675676	148	10287	5578	PRKCA
R-HSA-8854214	TBC/RABGAPs	0.479793982077955	-0.734398471218863	45	1	0.00675675675675676	148	10287	125058	TBC1D16
R-HSA-449147	Signaling by Interleukins	0.485798577710041	-0.721961190145726	525	8	0.0540540540540541	148	10287	54756,9462,1850,5608,5924,5777,4609,153090	IL17RD,RASAL2,DUSP8,MAP2K6,RASGRF2,PTPN6,MYC,DAB2IP
R-HSA-70153	Glucose transport	0.487311116491929	-0.718852516973568	46	1	0.00675675675675676	148	10287	3099	HK2
R-HSA-446652	Interleukin-1 signaling	0.487311116491929	-0.718852516973568	46	1	0.00675675675675676	148	10287	5608	MAP2K6
R-HSA-5173105	O-linked glycosylation	0.490527197176114	-0.712274553652296	114	2	0.0135135135135135	148	10287	145173,9508	B3GLCT,ADAMTS3
R-HSA-73779	RNA Polymerase II Transcription Pre-Initiation And Promoter Opening	0.494720349457007	-0.703762626650068	47	1	0.00675675675675676	148	10287	2963	GTF2F2
R-HSA-73776	RNA Polymerase II Promoter Escape	0.494720349457007	-0.703762626650068	47	1	0.00675675675675676	148	10287	2963	GTF2F2
R-HSA-167161	HIV Transcription Initiation	0.494720349457007	-0.703762626650068	47	1	0.00675675675675676	148	10287	2963	GTF2F2
R-HSA-76042	RNA Polymerase II Transcription Initiation And Promoter Clearance	0.494720349457007	-0.703762626650068	47	1	0.00675675675675676	148	10287	2963	GTF2F2
R-HSA-75953	RNA Polymerase II Transcription Initiation	0.494720349457007	-0.703762626650068	47	1	0.00675675675675676	148	10287	2963	GTF2F2
R-HSA-167162	RNA Polymerase II HIV Promoter Escape	0.494720349457007	-0.703762626650068	47	1	0.00675675675675676	148	10287	2963	GTF2F2
R-HSA-166054	Activated TLR4 signalling	0.495145005191045	-0.702904619532037	115	2	0.0135135135135135	148	10287	10333,5608	TLR6,MAP2K6
R-HSA-535734	Fatty acid, triacylglycerol, and ketone body metabolism	0.495874344880415	-0.701432721287078	253	4	0.027027027027027	148	10287	57761,2180,25937,26230	TRIB3,ACSL1,WWTR1,TIAM2
R-HSA-4570464	SUMOylation of RNA binding proteins	0.502023219407681	-0.68910890655992	48	1	0.00675675675675676	148	10287	1911	PHC1
R-HSA-2122947	NOTCH1 Intracellular Domain Regulates Transcription	0.502023219407681	-0.68910890655992	48	1	0.00675675675675676	148	10287	4609	MYC
R-HSA-1368108	BMAL1:CLOCK,NPAS2 activates circadian gene expression	0.502023219407681	-0.68910890655992	48	1	0.00675675675675676	148	10287	1628	DBP
R-HSA-6791312	TP53 Regulates Transcription of Cell Cycle Genes	0.509221242999894	-0.674872694787507	49	1	0.00675675675675676	148	10287	10769	PLK2
R-HSA-71406	Pyruvate metabolism and Citric Acid (TCA) cycle	0.509221242999894	-0.674872694787507	49	1	0.00675675675675676	148	10287	5163	PDK1
R-HSA-382551	Transmembrane transport of small molecules	0.513034539375601	-0.667412107860265	677	10	0.0675675675675676	148	10287	30061,285335,64116,107,3099,6446,90423,1244,114134,10110	SLC40A1,SLC9C1,SLC39A8,ADCY1,HK2,SGK1,ATP6V1E2,ABCC2,SLC2A13,SGK2
R-HSA-167246	Tat-mediated elongation of the HIV-1 transcript	0.51631591539575	-0.661036461703444	50	1	0.00675675675675676	148	10287	2963	GTF2F2
R-HSA-167200	Formation of HIV-1 elongation complex containing HIV-1 Tat	0.51631591539575	-0.661036461703444	50	1	0.00675675675675676	148	10287	2963	GTF2F2
R-HSA-1660499	Synthesis of PIPs at the plasma membrane	0.51631591539575	-0.661036461703444	50	1	0.00675675675675676	148	10287	59338	PLEKHA1
R-HSA-167169	HIV Transcription Elongation	0.51631591539575	-0.661036461703444	50	1	0.00675675675675676	148	10287	2963	GTF2F2
R-HSA-1793185	Chondroitin sulfate/dermatan sulfate metabolism	0.523308710598443	-0.647583720226663	51	1	0.00675675675675676	148	10287	11285	B4GALT7
R-HSA-416476	G alpha (q) signalling events	0.524558864693239	-0.645197627332075	192	3	0.0202702702702703	148	10287	3709,57406,5580	ITPR2,ABHD6,PRKCD
R-HSA-167152	Formation of HIV elongation complex in the absence of HIV Tat	0.530201081721192	-0.634498944915803	52	1	0.00675675675675676	148	10287	2963	GTF2F2
R-HSA-2980766	Nuclear Envelope Breakdown	0.530201081721192	-0.634498944915803	52	1	0.00675675675675676	148	10287	5578	PRKCA
R-HSA-445717	Aquaporin-mediated transport	0.530201081721192	-0.634498944915803	52	1	0.00675675675675676	148	10287	107	ADCY1
R-HSA-3214842	HDMs demethylate histones	0.530201081721192	-0.634498944915803	52	1	0.00675675675675676	148	10287	80853	KDM7A
R-HSA-72165	mRNA Splicing - Minor Pathway	0.536994461301305	-0.621767498676733	53	1	0.00675675675675676	148	10287	2963	GTF2F2
R-HSA-114604	GPVI-mediated activation cascade	0.543690261548961	-0.609375566432716	54	1	0.00675675675675676	148	10287	5777	PTPN6
R-HSA-1638091	Heparan sulfate/heparin (HS-GAG) metabolism	0.543690261548961	-0.609375566432716	54	1	0.00675675675675676	148	10287	11285	B4GALT7
R-HSA-189200	Hexose transport	0.543690261548961	-0.609375566432716	54	1	0.00675675675675676	148	10287	3099	HK2
R-HSA-2559580	Oxidative Stress Induced Senescence	0.544162516728363	-0.608507332755333	126	2	0.0135135135135135	148	10287	5608,1911	MAP2K6,PHC1
R-HSA-166016	Toll Like Receptor 4 (TLR4) Cascade	0.544162516728363	-0.608507332755333	126	2	0.0135135135135135	148	10287	10333,5608	TLR6,MAP2K6
R-HSA-75105	Fatty Acyl-CoA Biosynthesis	0.550289874696176	-0.597310094692866	55	1	0.00675675675675676	148	10287	2180	ACSL1
R-HSA-180292	GAB1 signalosome	0.552715597096469	-0.592911700717554	128	2	0.0135135135135135	148	10287	57761,5829	TRIB3,PXN
R-HSA-913531	Interferon Signaling	0.555662069611436	-0.587594957978481	201	3	0.0202702702702703	148	10287	10612,5777,5580	TRIM3,PTPN6,PRKCD
R-HSA-977443	GABA receptor activation	0.556794673220052	-0.58555873678202	56	1	0.00675675675675676	148	10287	107	ADCY1
R-HSA-5578775	Ion homeostasis	0.556794673220052	-0.58555873678202	56	1	0.00675675675675676	148	10287	3709	ITPR2
R-HSA-381038	XBP1(S) activates chaperone genes	0.556794673220052	-0.58555873678202	56	1	0.00675675675675676	148	10287	7466	WFS1
R-HSA-2894858	Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer	0.569525219415144	-0.562952213642295	58	1	0.00675675675675676	148	10287	4609	MYC
R-HSA-2644602	Signaling by NOTCH1 PEST Domain Mutants in Cancer	0.569525219415144	-0.562952213642295	58	1	0.00675675675675676	148	10287	4609	MYC
R-HSA-2644606	Constitutive Signaling by NOTCH1 PEST Domain Mutants	0.569525219415144	-0.562952213642295	58	1	0.00675675675675676	148	10287	4609	MYC
R-HSA-2894862	Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants	0.569525219415144	-0.562952213642295	58	1	0.00675675675675676	148	10287	4609	MYC
R-HSA-2644603	Signaling by NOTCH1 in Cancer	0.569525219415144	-0.562952213642295	58	1	0.00675675675675676	148	10287	4609	MYC
R-HSA-2142753	Arachidonic acid metabolism	0.575753615872753	-0.552075460018383	59	1	0.00675675675675676	148	10287	1573	CYP2J2
R-HSA-4641258	Degradation of DVL	0.575753615872753	-0.552075460018383	59	1	0.00675675675675676	148	10287	51339	DACT1
R-HSA-3906995	Diseases associated with O-glycosylation of proteins	0.575753615872753	-0.552075460018383	59	1	0.00675675675675676	148	10287	9508	ADAMTS3
R-HSA-2029482	Regulation of actin dynamics for phagocytic cup formation	0.587943137394221	-0.53112504087162	61	1	0.00675675675675676	148	10287	1793	DOCK1
R-HSA-5358351	Signaling by Hedgehog	0.593780665247139	-0.52124527823491	138	2	0.0135135135135135	148	10287	23432,107	GPR161,ADCY1
R-HSA-1445148	Translocation of GLUT4 to the plasma membrane	0.593906800192127	-0.52103287396336	62	1	0.00675675675675676	148	10287	22989	MYH15
R-HSA-425407	SLC-mediated transmembrane transport	0.595885037942311	-0.517707519880871	287	4	0.027027027027027	148	10287	30061,114134,64116,3099	SLC40A1,SLC2A13,SLC39A8,HK2
R-HSA-1226099	Signaling by FGFR in disease	0.599784726207587	-0.511184477800421	63	1	0.00675675675675676	148	10287	2963	GTF2F2
R-HSA-450294	MAP kinase activation in TLR cascade	0.605578139791872	-0.501571674287365	64	1	0.00675675675675676	148	10287	5608	MAP2K6
R-HSA-75955	RNA Polymerase II Transcription Elongation	0.611288247922289	-0.492186666862684	65	1	0.00675675675675676	148	10287	2963	GTF2F2
R-HSA-112382	Formation of RNA Pol II elongation complex	0.611288247922289	-0.492186666862684	65	1	0.00675675675675676	148	10287	2963	GTF2F2
R-HSA-5621481	C-type lectin receptors (CLRs)	0.617049003559143	-0.482806835930464	144	2	0.0135135135135135	148	10287	3709,5580	ITPR2,PRKCD
R-HSA-71387	Metabolism of carbohydrates	0.620345636422499	-0.477478478175385	296	4	0.027027027027027	148	10287	2597,226,11285,3099	GAPDH,ALDOA,B4GALT7,HK2
R-HSA-1280218	Adaptive Immune System	0.624301880600173	-0.471121244584884	810	11	0.0743243243243243	148	10287	91694,57761,26249,26272,5777,8139,64219,3709,55008,10333,1780	LONRF1,TRIB3,KLHL3,FBXO4,PTPN6,GAN,PJA1,ITPR2,HERC6,TLR6,DYNC1I1
R-HSA-216083	Integrin cell surface interactions	0.627930553773489	-0.465325701791941	68	1	0.00675675675675676	148	10287	83700	JAM3
R-HSA-5685942	HDR through Homologous Recombination (HRR)	0.627930553773489	-0.465325701791941	68	1	0.00675675675675676	148	10287	79008	SLX1B
R-HSA-909733	Interferon alpha/beta signaling	0.633319170847822	-0.456780764564973	69	1	0.00675675675675676	148	10287	5777	PTPN6
R-HSA-6796648	TP53 Regulates Transcription of DNA Repair Genes	0.633319170847822	-0.456780764564973	69	1	0.00675675675675676	148	10287	2963	GTF2F2
R-HSA-3371453	Regulation of HSF1-mediated heat shock response	0.638630265265794	-0.448429606674155	70	1	0.00675675675675676	148	10287	3306	HSPA2
R-HSA-6809371	Formation of the cornified envelope	0.643864944797007	-0.440266287918765	71	1	0.00675675675675676	148	10287	6768	ST14
R-HSA-73856	RNA Polymerase II Transcription Termination	0.643864944797007	-0.440266287918765	71	1	0.00675675675675676	148	10287	134353	LSM11
R-HSA-69656	Cyclin A:Cdk2-associated events at S phase entry	0.643864944797007	-0.440266287918765	71	1	0.00675675675675676	148	10287	4609	MYC
R-HSA-400253	Circadian Clock	0.643864944797007	-0.440266287918765	71	1	0.00675675675675676	148	10287	1628	DBP
R-HSA-109688	Cleavage of Growing Transcript in the Termination Region	0.643864944797007	-0.440266287918765	71	1	0.00675675675675676	148	10287	134353	LSM11
R-HSA-983705	Signaling by the B Cell Receptor (BCR)	0.644304642243504	-0.439583617767261	229	3	0.0202702702702703	148	10287	57761,3709,5777	TRIB3,ITPR2,PTPN6
R-HSA-69202	Cyclin E associated events during G1/S transition	0.649024301505914	-0.432285118439918	72	1	0.00675675675675676	148	10287	4609	MYC
R-HSA-168898	Toll-Like Receptors Cascades	0.650027452316902	-0.430740682650603	153	2	0.0135135135135135	148	10287	10333,5608	TLR6,MAP2K6
R-HSA-1980143	Signaling by NOTCH1	0.654109411970669	-0.424480644926215	73	1	0.00675675675675676	148	10287	4609	MYC
R-HSA-6807505	RNA polymerase II transcribes snRNA genes	0.654109411970669	-0.424480644926215	73	1	0.00675675675675676	148	10287	2963	GTF2F2
R-HSA-3214841	PKMTs methylate histone lysines	0.654109411970669	-0.424480644926215	73	1	0.00675675675675676	148	10287	64754	SMYD3
R-HSA-174824	Lipoprotein metabolism	0.659121337464671	-0.416847637809681	74	1	0.00675675675675676	148	10287	57552	NCEH1
R-HSA-5654738	Signaling by FGFR2	0.664061124216442	-0.409381079199628	75	1	0.00675675675675676	148	10287	2963	GTF2F2
R-HSA-73857	RNA Polymerase II Transcription	0.670745032037719	-0.399366196281963	159	2	0.0135135135135135	148	10287	134353,2963	LSM11,GTF2F2
R-HSA-167172	Transcription of the HIV genome	0.673728392252866	-0.394928228140942	77	1	0.00675675675675676	148	10287	2963	GTF2F2
R-HSA-3108214	SUMOylation of DNA damage response and repair proteins	0.678457892532555	-0.387932861275505	78	1	0.00675675675675676	148	10287	1911	PHC1
R-HSA-418594	G alpha (i) signalling events	0.681025283409956	-0.384155846634944	242	3	0.0202702702702703	148	10287	6004,50865,107	RGS16,HEBP1,ADCY1
R-HSA-1483255	PI Metabolism	0.683119292491041	-0.381085775085628	79	1	0.00675675675675676	148	10287	59338	PLEKHA1
R-HSA-6807878	COPI-mediated anterograde transport	0.683119292491041	-0.381085775085628	79	1	0.00675675675675676	148	10287	1780	DYNC1I1
R-HSA-1221632	Meiotic synapsis	0.683119292491041	-0.381085775085628	79	1	0.00675675675675676	148	10287	3306	HSPA2
R-HSA-75109	Triglyceride Biosynthesis	0.696704561191435	-0.361393830116002	82	1	0.00675675675675676	148	10287	2180	ACSL1
R-HSA-6811434	COPI-dependent Golgi-to-ER retrograde traffic	0.696704561191435	-0.361393830116002	82	1	0.00675675675675676	148	10287	23046	KIF21B
R-HSA-195253	Degradation of beta-catenin by the destruction complex	0.701103162375671	-0.355100238187929	83	1	0.00675675675675676	148	10287	83439	TCF7L1
R-HSA-975871	MyD88 cascade initiated on plasma membrane	0.705438396799353	-0.348935830000186	84	1	0.00675675675675676	148	10287	5608	MAP2K6
R-HSA-168176	Toll Like Receptor 5 (TLR5) Cascade	0.705438396799353	-0.348935830000186	84	1	0.00675675675675676	148	10287	5608	MAP2K6
R-HSA-168142	Toll Like Receptor 10 (TLR10) Cascade	0.705438396799353	-0.348935830000186	84	1	0.00675675675675676	148	10287	5608	MAP2K6
R-HSA-6798695	Neutrophil degranulation	0.70817365423807	-0.345065941015696	487	6	0.0405405405405405	148	10287	5768,2268,9522,5777,226,5580	QSOX1,FGR,SCAMP1,PTPN6,ALDOA,PRKCD
R-HSA-3781865	Diseases of glycosylation	0.709711171195811	-0.342897192845465	85	1	0.00675675675675676	148	10287	9508	ADAMTS3
R-HSA-1236974	ER-Phagosome pathway	0.709711171195811	-0.342897192845465	85	1	0.00675675675675676	148	10287	10333	TLR6
R-HSA-5632684	Hedgehog 'on' state	0.71392237943916	-0.336981034822243	86	1	0.00675675675675676	148	10287	23432	GPR161
R-HSA-446728	Cell junction organization	0.722163609620109	-0.325503559638565	88	1	0.00675675675675676	148	10287	5829	PXN
R-HSA-674695	RNA Polymerase II Pre-transcription Events	0.722163609620109	-0.325503559638565	88	1	0.00675675675675676	148	10287	2963	GTF2F2
R-HSA-381340	Transcriptional regulation of white adipocyte differentiation	0.722163609620109	-0.325503559638565	88	1	0.00675675675675676	148	10287	1050	CEBPA
R-HSA-3371556	Cellular response to heat stress	0.726195356439312	-0.319936214349925	89	1	0.00675675675675676	148	10287	3306	HSPA2
R-HSA-190236	Signaling by FGFR	0.726195356439312	-0.319936214349925	89	1	0.00675675675675676	148	10287	2963	GTF2F2
R-HSA-5687128	MAPK6/MAPK4 signaling	0.730168987275708	-0.314479282210463	90	1	0.00675675675675676	148	10287	4609	MYC
R-HSA-6811442	Intra-Golgi and retrograde Golgi-to-ER traffic	0.732736645506416	-0.31096892472758	179	2	0.0135135135135135	148	10287	23046,1780	KIF21B,DYNC1I1
R-HSA-975138	TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation	0.734085334227387	-0.309129997959818	91	1	0.00675675675675676	148	10287	5608	MAP2K6
R-HSA-2980736	Peptide hormone metabolism	0.734085334227387	-0.309129997959818	91	1	0.00675675675675676	148	10287	3800	KIF5C
R-HSA-373080	Class B/2 (Secretin family receptors)	0.737945217563988	-0.303885688080023	92	1	0.00675675675675676	148	10287	7481	WNT11
R-HSA-975155	MyD88 dependent cascade initiated on endosome	0.741749445894896	-0.298743766835556	93	1	0.00675675675675676	148	10287	5608	MAP2K6
R-HSA-168181	Toll Like Receptor 7/8 (TLR7/8) Cascade	0.741749445894896	-0.298743766835556	93	1	0.00675675675675676	148	10287	5608	MAP2K6
R-HSA-199418	Negative regulation of the PI3K/AKT network	0.745498816305911	-0.293701732564103	94	1	0.00675675675675676	148	10287	57761	TRIB3
R-HSA-15869	Metabolism of nucleotides	0.756425581941711	-0.279151122117029	97	1	0.00675675675675676	148	10287	64077	LHPP
R-HSA-6803157	Antimicrobial peptides	0.756425581941711	-0.279151122117029	97	1	0.00675675675675676	148	10287	475	ATOX1
R-HSA-168138	Toll Like Receptor 9 (TLR9) Cascade	0.756425581941711	-0.279151122117029	97	1	0.00675675675675676	148	10287	5608	MAP2K6
R-HSA-8856825	Cargo recognition for clathrin-mediated endocytosis	0.763449913338466	-0.269907757865667	99	1	0.00675675675675676	148	10287	157	GRK3
R-HSA-937061	TRIF-mediated TLR3/TLR4 signaling	0.763449913338466	-0.269907757865667	99	1	0.00675675675675676	148	10287	5608	MAP2K6
R-HSA-166166	MyD88-independent TLR3/TLR4 cascade	0.763449913338466	-0.269907757865667	99	1	0.00675675675675676	148	10287	5608	MAP2K6
R-HSA-168164	Toll Like Receptor 3 (TLR3) Cascade	0.763449913338466	-0.269907757865667	99	1	0.00675675675675676	148	10287	5608	MAP2K6
R-HSA-5620912	Anchoring of the basal body to the plasma membrane	0.76688625146301	-0.265416791790186	100	1	0.00675675675675676	148	10287	27077	B9D1
R-HSA-5617833	Cilium Assembly	0.767527967489167	-0.264580360459396	192	2	0.0135135135135135	148	10287	27077,28981	B9D1,IFT81
R-HSA-977225	Amyloid fiber formation	0.770273002706658	-0.261010278002355	101	1	0.00675675675675676	148	10287	23621	BACE1
R-HSA-373760	L1CAM interactions	0.770273002706658	-0.261010278002355	101	1	0.00675675675675676	148	10287	6331	SCN5A
R-HSA-1236975	Antigen processing-Cross presentation	0.770273002706658	-0.261010278002355	101	1	0.00675675675675676	148	10287	10333	TLR6
R-HSA-2132295	MHC class II antigen presentation	0.776900577349623	-0.252442893880687	103	1	0.00675675675675676	148	10287	1780	DYNC1I1
R-HSA-2559583	Cellular Senescence	0.777417718314097	-0.251777469063906	196	2	0.0135135135135135	148	10287	5608,1911	MAP2K6,PHC1
R-HSA-3108232	SUMO E3 ligases SUMOylate target proteins	0.78014279204703	-0.248278309326207	104	1	0.00675675675675676	148	10287	1911	PHC1
R-HSA-199991	Membrane Trafficking	0.782304081819593	-0.245511762588246	610	7	0.0472972972972973	148	10287	22989,23682,23046,5874,125058,1780,157	MYH15,RAB38,KIF21B,RAB27B,TBC1D16,DYNC1I1,GRK3
R-HSA-382556	ABC-family proteins mediated transport	0.78959128684829	-0.236239825817	107	1	0.00675675675675676	148	10287	1244	ABCC2
R-HSA-2990846	SUMOylation	0.798636353032427	-0.224849564436863	110	1	0.00675675675675676	148	10287	1911	PHC1
R-HSA-6785807	Interleukin-4 and 13 signaling	0.801564703227587	-0.22118958252073	111	1	0.00675675675675676	148	10287	4609	MYC
R-HSA-1474228	Degradation of the extracellular matrix	0.801564703227587	-0.22118958252073	111	1	0.00675675675675676	148	10287	726	CAPN5
R-HSA-1483257	Phospholipid metabolism	0.802750405619266	-0.219711440725483	207	2	0.0135135135135135	148	10287	59338,63874	PLEKHA1,ABHD4
R-HSA-392499	Metabolism of proteins	0.804022104901162	-0.218128516522952	1619	20	0.135135135135135	148	10287	145173,8434,26272,23621,402,3800,51299,23682,2621,1780,2822,11328,9508,7466,4609,2775,2081,5874,1649,1911	B3GLCT,RECK,FBXO4,BACE1,ARL2,KIF5C,NRN1,RAB38,GAS6,DYNC1I1,GPLD1,FKBP9,ADAMTS3,WFS1,MYC,GNAO1,ERN1,RAB27B,DDIT3,PHC1
R-HSA-157118	Signaling by NOTCH	0.804450751170957	-0.217595531115926	112	1	0.00675675675675676	148	10287	4609	MYC
R-HSA-73923	Lipid digestion, mobilization, and transport	0.812861108412518	-0.207195022389847	115	1	0.00675675675675676	148	10287	57552	NCEH1
R-HSA-5663220	RHO GTPases Activate Formins	0.818267401929724	-0.200566098574045	117	1	0.00675675675675676	148	10287	5217	PFN2
R-HSA-69206	G1/S Transition	0.823518536872726	-0.194169219754123	119	1	0.00675675675675676	148	10287	4609	MYC
R-HSA-1500620	Meiosis	0.828618936812808	-0.187994895613974	121	1	0.00675675675675676	148	10287	3306	HSPA2
R-HSA-196849	Metabolism of water-soluble vitamins and cofactors	0.831113959177269	-0.184988358538135	122	1	0.00675675675675676	148	10287	83666	PARP9
R-HSA-211859	Biological oxidations	0.833185723211698	-0.182498704629669	222	2	0.0135135135135135	148	10287	1573,285440	CYP2J2,CYP4V2
R-HSA-5653656	Vesicle-mediated transport	0.834080015954889	-0.181425938833614	650	7	0.0472972972972973	148	10287	22989,23682,23046,5874,125058,1780,157	MYH15,RAB38,KIF21B,RAB27B,TBC1D16,DYNC1I1,GRK3
R-HSA-1630316	Glycosaminoglycan metabolism	0.83599627774566	-0.179131118364692	124	1	0.00675675675675676	148	10287	11285	B4GALT7
R-HSA-1257604	PIP3 activates AKT signaling	0.838384603146318	-0.176278330151836	125	1	0.00675675675675676	148	10287	57761	TRIB3
R-HSA-5617472	Activation of anterior HOX genes in hindbrain development during early embryogenesis	0.840738379813049	-0.173474749672795	126	1	0.00675675675675676	148	10287	9935	MAFB
R-HSA-5619507	Activation of HOX genes during differentiation	0.840738379813049	-0.173474749672795	126	1	0.00675675675675676	148	10287	9935	MAFB
R-HSA-198203	PI3K/AKT activation	0.845344265732239	-0.168011319528208	128	1	0.00675675675675676	148	10287	57761	TRIB3
R-HSA-1483206	Glycerophospholipid biosynthesis	0.847597346605519	-0.16534958307246	129	1	0.00675675675675676	148	10287	63874	ABHD4
R-HSA-69242	S Phase	0.849817822363534	-0.162733279100146	130	1	0.00675675675675676	148	10287	4609	MYC
R-HSA-2730905	Role of LAT2/NTAL/LAB on calcium mobilization	0.852006161647606	-0.160161520198214	131	1	0.00675675675675676	148	10287	57761	TRIB3
R-HSA-5693567	HDR through Homologous Recombination (HR) or Single Strand Annealing (SSA)	0.854162826502815	-0.157633440015272	132	1	0.00675675675675676	148	10287	79008	SLX1B
R-HSA-199977	ER to Golgi Anterograde Transport	0.856288272227707	-0.155148192912392	133	1	0.00675675675675676	148	10287	1780	DYNC1I1
R-HSA-8856828	Clathrin-mediated endocytosis	0.864486746597498	-0.145619304690596	137	1	0.00675675675675676	148	10287	157	GRK3
R-HSA-168273	Influenza Viral RNA Transcription and Replication	0.864486746597498	-0.145619304690596	137	1	0.00675675675675676	148	10287	2963	GTF2F2
R-HSA-5693538	Homology Directed Repair	0.866462703408994	-0.143336213558391	138	1	0.00675675675675676	148	10287	79008	SLX1B
R-HSA-162599	Late Phase of HIV Life Cycle	0.868410040085488	-0.141091279453991	139	1	0.00675675675675676	148	10287	2963	GTF2F2
R-HSA-1430728	Metabolism	0.871688289998931	-0.137323384576771	2158	26	0.175675675675676	148	10287	2597,2180,5163,7390,1573,51700,645,107,285440,402,81894,64077,3709,59338,5578,63874,26230,57761,8564,226,25937,3099,57552,6812,11285,83666	GAPDH,ACSL1,PDK1,UROS,CYP2J2,CYB5R2,BLVRB,ADCY1,CYP4V2,ARL2,SLC25A28,LHPP,ITPR2,PLEKHA1,PRKCA,ABHD4,TIAM2,TRIB3,KMO,ALDOA,WWTR1,HK2,NCEH1,STXBP1,B4GALT7,PARP9
R-HSA-68875	Mitotic Prophase	0.872220494204829	-0.136713026710303	141	1	0.00675675675675676	148	10287	5578	PRKCA
R-HSA-453279	Mitotic G1-G1/S phases	0.875921332963753	-0.132478994631029	143	1	0.00675675675675676	148	10287	4609	MYC
R-HSA-1643685	Disease	0.879683393525218	-0.128193216331247	859	9	0.0608108108108108	148	10287	80853,9462,9508,5608,4609,2963,153090,10333,57670	KDM7A,RASAL2,ADAMTS3,MAP2K6,MYC,GTF2F2,DAB2IP,TLR6,KIAA1549
R-HSA-168255	Influenza Life Cycle	0.881273890140009	-0.126386815844377	146	1	0.00675675675675676	148	10287	2963	GTF2F2
R-HSA-597592	Post-translational protein modification	0.88990322036084	-0.116642563336297	1034	11	0.0743243243243243	148	10287	145173,9508,8434,4609,51299,2621,23682,5874,1780,2822,1911	B3GLCT,ADAMTS3,RECK,MYC,NRN1,GAS6,RAB38,RAB27B,DYNC1I1,GPLD1,PHC1
R-HSA-162587	HIV Life Cycle	0.891300549463445	-0.115073591371466	152	1	0.00675675675675676	148	10287	2963	GTF2F2
R-HSA-2262752	Cellular responses to stress	0.894413443110957	-0.111587146382363	451	4	0.027027027027027	148	10287	3306,5608,475,1911	HSPA2,MAP2K6,ATOX1,PHC1
R-HSA-168254	Influenza Infection	0.899010207246388	-0.106460890574541	157	1	0.00675675675675676	148	10287	2963	GTF2F2
R-HSA-1428517	The citric acid (TCA) cycle and respiratory electron transport	0.900485675093056	-0.104821022218302	158	1	0.00675675675675676	148	10287	5163	PDK1
R-HSA-556833	Metabolism of lipids and lipoproteins	0.907336106070151	-0.0972423285248958	813	8	0.0540540540540541	148	10287	57761,59338,2180,57552,63874,1573,25937,26230	TRIB3,PLEKHA1,ACSL1,NCEH1,ABHD4,CYP2J2,WWTR1,TIAM2
R-HSA-948021	Transport to the Golgi and subsequent modification	0.908899456559097	-0.0955207997681456	164	1	0.00675675675675676	148	10287	1780	DYNC1I1
R-HSA-5693532	DNA Double-Strand Break Repair	0.912837423320248	-0.0911974828957949	167	1	0.00675675675675676	148	10287	79008	SLX1B
R-HSA-4839726	Chromatin organization	0.913962375791892	-0.0899658727167365	279	2	0.0135135135135135	148	10287	80853,64754	KDM7A,SMYD3
R-HSA-3247509	Chromatin modifying enzymes	0.913962375791892	-0.0899658727167365	279	2	0.0135135135135135	148	10287	80853,64754	KDM7A,SMYD3
R-HSA-196854	Metabolism of vitamins and cofactors	0.921380734790868	-0.0818819353261412	174	1	0.00675675675675676	148	10287	83666	PARP9
R-HSA-195258	RHO GTPase Effectors	0.928128983934114	-0.0745845645460209	294	2	0.0135135135135135	148	10287	85415,5217	RHPN2,PFN2
R-HSA-72163	mRNA Splicing - Major Pathway	0.935100098811077	-0.0671016978717463	187	1	0.00675675675675676	148	10287	2963	GTF2F2
R-HSA-375276	Peptide ligand-binding receptors	0.936051107254429	-0.0660852022276152	188	1	0.00675675675675676	148	10287	50865	HEBP1
R-HSA-72172	mRNA Splicing	0.942331577669892	-0.0593980730607354	195	1	0.00675675675675676	148	10287	2963	GTF2F2
R-HSA-1168372	Downstream signaling events of B Cell Receptor (BCR)	0.944010682014422	-0.0576177972074144	197	1	0.00675675675675676	148	10287	57761	TRIB3
R-HSA-373076	Class A/1 (Rhodopsin-like receptors)	0.948905944214001	-0.0524455957012519	322	2	0.0135135135135135	148	10287	7253,50865	TSHR,HEBP1
R-HSA-6805567	Keratinization	0.956456632326934	-0.044519831091103	214	1	0.00675675675675676	148	10287	6768	ST14
R-HSA-1852241	Organelle biogenesis and maintenance	0.959107749175531	-0.0417518546483714	340	2	0.0135135135135135	148	10287	27077,28981	B9D1,IFT81
R-HSA-500792	GPCR ligand binding	0.961593146661912	-0.0391638422420734	453	3	0.0202702702702703	148	10287	7481,7253,50865	WNT11,TSHR,HEBP1
R-HSA-5689880	Ub-specific processing proteases	0.961889557646684	-0.0388556398480988	223	1	0.00675675675675676	148	10287	4609	MYC
R-HSA-162906	HIV Infection	0.968569573109982	-0.0319349627730038	236	1	0.00675675675675676	148	10287	2963	GTF2F2
R-HSA-72203	Processing of Capped Intron-Containing Pre-mRNA	0.973303931698865	-0.0270588800028647	247	1	0.00675675675675676	148	10287	2963	GTF2F2
R-HSA-74160	Gene Expression	0.974877776533833	-0.0254431732433829	1821	18	0.121621621621622	148	10287	860,134353,665,639,8794,5578,148156,79047,5366,90874,4609,10769,5608,25937,5580,2963,6446,284252	RUNX2,LSM11,BNIP3L,PRDM1,TNFRSF10C,PRKCA,ZNF558,KCTD15,PMAIP1,ZNF697,MYC,PLK2,MAP2K6,WWTR1,PRKCD,GTF2F2,SGK1,KCTD1
R-HSA-5663205	Infectious disease	0.977678414639774	-0.0225744824070023	388	2	0.0135135135135135	148	10287	5608,2963	MAP2K6,GTF2F2
R-HSA-381753	Olfactory Signaling Pathway	0.97851813834293	-0.0217159554318337	391	2	0.0135135135135135	148	10287	390442,343171	OR11H4,OR2W3
R-HSA-446203	Asparagine N-linked glycosylation	0.984604994977498	-0.015514738567616	284	1	0.00675675675675676	148	10287	1780	DYNC1I1
R-HSA-5688426	Deubiquitination	0.988053541520053	-0.0120183908806768	301	1	0.00675675675675676	148	10287	4609	MYC
R-HSA-68886	M Phase	0.98923950553308	-0.0108188072812587	308	1	0.00675675675675676	148	10287	5578	PRKCA
R-HSA-73894	DNA Repair	0.990452289066502	-0.00959358253824857	316	1	0.00675675675675676	148	10287	79008	SLX1B
R-HSA-1640170	Cell Cycle	0.994716829442671	-0.00529717585292032	621	3	0.0202702702702703	148	10287	5578,3306,4609	PRKCA,HSPA2,MYC
R-HSA-71291	Metabolism of amino acids and derivatives	0.995136018899896	-0.00487584875451161	361	1	0.00675675675675676	148	10287	8564	KMO
R-HSA-69278	Cell Cycle, Mitotic	0.995729022721116	-0.00428012395513011	514	2	0.0135135135135135	148	10287	5578,4609	PRKCA,MYC
R-HSA-110314	Recognition of DNA damage by PCNA-containing replication complex	0.999999999966363	-3.36366093410418e-11	30	0	0	148	10287
R-HSA-157858	Gap junction trafficking and regulation	0.999999999966363	-3.36366093410418e-11	30	0	0	148	10287
R-HSA-2122948	Activated NOTCH1 Transmits Signal to the Nucleus	0.999999999966363	-3.36366093410418e-11	30	0	0	148	10287
R-HSA-420092	Glucagon-type ligand receptors	0.999999999966363	-3.36366093410418e-11	30	0	0	148	10287
R-HSA-8866652	Synthesis of active ubiquitin: roles of E1 and E2 enzymes	0.999999999966363	-3.36366093410418e-11	30	0	0	148	10287
R-HSA-1912408	Pre-NOTCH Transcription and Translation	0.999999999966363	-3.36366093410418e-11	30	0	0	148	10287
R-HSA-8863795	Downregulation of ERBB2 signaling	0.999999999966363	-3.36366093410418e-11	30	0	0	148	10287
R-HSA-5654696	Downstream signaling of activated FGFR2	0.999999999966363	-3.36366093410418e-11	30	0	0	148	10287
R-HSA-420029	Tight junction interactions	0.999999999966363	-3.36366093410418e-11	30	0	0	148	10287
R-HSA-5683826	Surfactant metabolism	0.999999999966363	-3.36366093410418e-11	30	0	0	148	10287
R-HSA-1482883	Acyl chain remodeling of DAG and TAG	0.999999999966797	-3.32028514208219e-11	8	0	0	148	10287
R-HSA-68952	DNA replication initiation	0.999999999966797	-3.32028514208219e-11	8	0	0	148	10287
R-HSA-70921	Histidine catabolism	0.999999999966797	-3.32028514208219e-11	8	0	0	148	10287
R-HSA-196836	Vitamin C (ascorbate) metabolism	0.999999999966797	-3.32028514208219e-11	8	0	0	148	10287
R-HSA-164944	Nef and signal transduction	0.999999999966797	-3.32028514208219e-11	8	0	0	148	10287
R-HSA-3656534	Loss of Function of TGFBR1 in Cancer	0.999999999966797	-3.32028514208219e-11	8	0	0	148	10287
R-HSA-1253288	Downregulation of ERBB4 signaling	0.999999999966797	-3.32028514208219e-11	8	0	0	148	10287
R-HSA-416550	Sema4D mediated inhibition of cell attachment and migration	0.999999999966797	-3.32028514208219e-11	8	0	0	148	10287
R-HSA-6787450	tRNA modification in the mitochondrion	0.999999999966797	-3.32028514208219e-11	8	0	0	148	10287
R-HSA-977347	Serine biosynthesis	0.999999999966797	-3.32028514208219e-11	8	0	0	148	10287
R-HSA-1483115	Hydrolysis of LPC	0.999999999966797	-3.32028514208219e-11	8	0	0	148	10287
R-HSA-195399	VEGF binds to VEGFR leading to receptor dimerization	0.999999999966797	-3.32028514208219e-11	8	0	0	148	10287
R-HSA-400451	Free fatty acids regulate insulin secretion	0.999999999966797	-3.32028514208219e-11	8	0	0	148	10287
R-HSA-434316	Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion	0.999999999966797	-3.32028514208219e-11	8	0	0	148	10287
R-HSA-8850843	Phosphate bond hydrolysis by NTPDase proteins	0.999999999966797	-3.32028514208219e-11	8	0	0	148	10287
R-HSA-5688849	Defective CSF2RB causes pulmonary surfactant metabolism dysfunction 5 (SMDP5)	0.999999999966797	-3.32028514208219e-11	8	0	0	148	10287
R-HSA-2408508	Metabolism of ingested SeMet, Sec, MeSec into H2Se	0.999999999966797	-3.32028514208219e-11	8	0	0	148	10287
R-HSA-73928	Depyrimidination	0.999999999966797	-3.32028514208219e-11	8	0	0	148	10287
R-HSA-110329	Cleavage of the damaged pyrimidine	0.999999999966797	-3.32028514208219e-11	8	0	0	148	10287
R-HSA-804914	Transport of fatty acids	0.999999999966797	-3.32028514208219e-11	8	0	0	148	10287
R-HSA-77111	Synthesis of Ketone Bodies	0.999999999966797	-3.32028514208219e-11	8	0	0	148	10287
R-HSA-5688890	Defective CSF2RA causes pulmonary surfactant metabolism dysfunction 4 (SMDP4)	0.999999999966797	-3.32028514208219e-11	8	0	0	148	10287
R-HSA-5576890	Phase 3 - rapid repolarisation	0.999999999966797	-3.32028514208219e-11	8	0	0	148	10287
R-HSA-8937144	Aryl hydrocarbon receptor signalling	0.999999999966797	-3.32028514208219e-11	8	0	0	148	10287
R-HSA-5603027	IKBKG deficiency causes anhidrotic ectodermal dysplasia with immunodeficiency (EDA-ID) (via TLR)	0.999999999966797	-3.32028514208219e-11	8	0	0	148	10287
R-HSA-196783	Coenzyme A biosynthesis	0.999999999966797	-3.32028514208219e-11	8	0	0	148	10287
R-HSA-444821	Relaxin receptors	0.999999999966797	-3.32028514208219e-11	8	0	0	148	10287
R-HSA-5358493	Synthesis of diphthamide-EEF2	0.999999999966797	-3.32028514208219e-11	8	0	0	148	10287
R-HSA-448424	Interleukin-17 signaling	0.999999999966797	-3.32028514208219e-11	8	0	0	148	10287
R-HSA-174430	Telomere C-strand synthesis initiation	0.999999999966797	-3.32028514208219e-11	8	0	0	148	10287
R-HSA-177128	Conjugation of salicylate with glycine	0.999999999966797	-3.32028514208219e-11	8	0	0	148	10287
R-HSA-389397	Orexin and neuropeptides FF and QRFP bind to their respective receptors	0.999999999966797	-3.32028514208219e-11	8	0	0	148	10287
R-HSA-5362798	Release of Hh-Np from the secreting cell	0.999999999966797	-3.32028514208219e-11	8	0	0	148	10287
R-HSA-194313	VEGF ligand-receptor interactions	0.999999999966797	-3.32028514208219e-11	8	0	0	148	10287
R-HSA-72731	Recycling of eIF2:GDP	0.999999999966797	-3.32028514208219e-11	8	0	0	148	10287
R-HSA-163680	AMPK inhibits chREBP transcriptional activation activity	0.999999999966797	-3.32028514208219e-11	8	0	0	148	10287
R-HSA-73942	DNA Damage Reversal	0.999999999966797	-3.32028514208219e-11	8	0	0	148	10287
R-HSA-5632681	Ligand-receptor interactions	0.999999999966797	-3.32028514208219e-11	8	0	0	148	10287
R-HSA-3656532	TGFBR1 KD Mutants in Cancer	0.999999999966797	-3.32028514208219e-11	8	0	0	148	10287
R-HSA-210747	Regulation of gene expression in early pancreatic precursor cells	0.999999999966797	-3.32028514208219e-11	8	0	0	148	10287
R-HSA-1236973	Cross-presentation of particulate exogenous antigens (phagosomes)	0.999999999966797	-3.32028514208219e-11	8	0	0	148	10287
R-HSA-1483148	Synthesis of PG	0.999999999966797	-3.32028514208219e-11	8	0	0	148	10287
R-HSA-2142789	Ubiquinol biosynthesis	0.999999999966797	-3.32028514208219e-11	8	0	0	148	10287
R-HSA-193634	Axonal growth inhibition (RHOA activation)	0.999999999966797	-3.32028514208219e-11	8	0	0	148	10287
R-HSA-110328	Recognition and association of DNA glycosylase with site containing an affected pyrimidine	0.999999999966797	-3.32028514208219e-11	8	0	0	148	10287
R-HSA-446210	Synthesis of UDP-N-acetyl-glucosamine	0.999999999966797	-3.32028514208219e-11	8	0	0	148	10287
R-HSA-425561	Sodium/Calcium exchangers	0.99999999996926	-3.07396573444124e-11	13	0	0	148	10287
R-HSA-264870	Caspase-mediated cleavage of cytoskeletal proteins	0.99999999996926	-3.07396573444124e-11	13	0	0	148	10287
R-HSA-211227	Activation of DNA fragmentation factor	0.99999999996926	-3.07396573444124e-11	13	0	0	148	10287
R-HSA-8866907	Activation of the TFAP2 (AP-2) family of transcription factors	0.99999999996926	-3.07396573444124e-11	13	0	0	148	10287
R-HSA-933543	NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10	0.99999999996926	-3.07396573444124e-11	13	0	0	148	10287
R-HSA-400511	Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)	0.99999999996926	-3.07396573444124e-11	13	0	0	148	10287
R-HSA-350054	Notch-HLH transcription pathway	0.99999999996926	-3.07396573444124e-11	13	0	0	148	10287
R-HSA-5357786	TNFR1-induced proapoptotic signaling	0.99999999996926	-3.07396573444124e-11	13	0	0	148	10287
R-HSA-75205	Dissolution of Fibrin Clot	0.99999999996926	-3.07396573444124e-11	13	0	0	148	10287
R-HSA-3270619	IRF3-mediated induction of type I IFN	0.99999999996926	-3.07396573444124e-11	13	0	0	148	10287
R-HSA-879415	Advanced glycosylation endproduct receptor signaling	0.99999999996926	-3.07396573444124e-11	13	0	0	148	10287
R-HSA-2197563	NOTCH2 intracellular domain regulates transcription	0.99999999996926	-3.07396573444124e-11	13	0	0	148	10287
R-HSA-977441	GABA A receptor activation	0.99999999996926	-3.07396573444124e-11	13	0	0	148	10287
R-HSA-5654227	Phospholipase C-mediated cascade; FGFR3	0.99999999996926	-3.07396573444124e-11	13	0	0	148	10287
R-HSA-198323	AKT phosphorylates targets in the cytosol	0.99999999996926	-3.07396573444124e-11	13	0	0	148	10287
R-HSA-3134963	DEx/H-box helicases activate type I IFN and inflammatory cytokines production	0.99999999996926	-3.07396573444124e-11	13	0	0	148	10287
R-HSA-2168880	Scavenging of heme from plasma	0.99999999996926	-3.07396573444124e-11	13	0	0	148	10287
R-HSA-2995383	Initiation of Nuclear Envelope Reformation	0.99999999996926	-3.07396573444124e-11	13	0	0	148	10287
R-HSA-74217	Purine salvage	0.99999999996926	-3.07396573444124e-11	13	0	0	148	10287
R-HSA-2892247	POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation	0.99999999996926	-3.07396573444124e-11	13	0	0	148	10287
R-HSA-140342	Apoptosis induced DNA fragmentation	0.99999999996926	-3.07396573444124e-11	13	0	0	148	10287
R-HSA-190239	FGFR3 ligand binding and activation	0.99999999996926	-3.07396573444124e-11	13	0	0	148	10287
R-HSA-5140745	WNT5A-dependent internalization of FZD2, FZD5 and ROR2	0.99999999996926	-3.07396573444124e-11	13	0	0	148	10287
R-HSA-1358803	Downregulation of ERBB2:ERBB3 signaling	0.99999999996926	-3.07396573444124e-11	13	0	0	148	10287
R-HSA-2995410	Nuclear Envelope Reassembly	0.99999999996926	-3.07396573444124e-11	13	0	0	148	10287
R-HSA-202670	ERKs are inactivated	0.99999999996926	-3.07396573444124e-11	13	0	0	148	10287
R-HSA-5626467	RHO GTPases activate IQGAPs	0.99999999996926	-3.07396573444124e-11	13	0	0	148	10287
R-HSA-5658623	FGFRL1 modulation of FGFR1 signaling	0.99999999996926	-3.07396573444124e-11	13	0	0	148	10287
R-HSA-2408517	SeMet incorporation into proteins	0.99999999996926	-3.07396573444124e-11	13	0	0	148	10287
R-HSA-6804116	TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest	0.99999999996926	-3.07396573444124e-11	13	0	0	148	10287
R-HSA-113501	Inhibition of replication initiation of damaged DNA by RB1/E2F1	0.99999999996926	-3.07396573444124e-11	13	0	0	148	10287
R-HSA-2564830	Cytosolic iron-sulfur cluster assembly	0.99999999996926	-3.07396573444124e-11	13	0	0	148	10287
R-HSA-75892	Platelet Adhesion to exposed collagen	0.99999999996926	-3.07396573444124e-11	13	0	0	148	10287
R-HSA-5668599	RHO GTPases Activate NADPH Oxidases	0.99999999996926	-3.07396573444124e-11	13	0	0	148	10287
R-HSA-190375	FGFR2c ligand binding and activation	0.99999999996926	-3.07396573444124e-11	13	0	0	148	10287
R-HSA-1663150	The activation of arylsulfatases	0.99999999996926	-3.07396573444124e-11	13	0	0	148	10287
R-HSA-8847993	ERBB2 Activates PTK6 Signaling	0.99999999996926	-3.07396573444124e-11	13	0	0	148	10287
R-HSA-175474	Assembly Of The HIV Virion	0.99999999996926	-3.07396573444124e-11	13	0	0	148	10287
R-HSA-190372	FGFR3c ligand binding and activation	0.99999999996926	-3.07396573444124e-11	13	0	0	148	10287
R-HSA-432047	Passive transport by Aquaporins	0.99999999996926	-3.07396573444124e-11	13	0	0	148	10287
R-HSA-68827	CDT1 association with the CDC6:ORC:origin complex	0.999999999972049	-2.79510661241277e-11	60	0	0	148	10287
R-HSA-2022090	Assembly of collagen fibrils and other multimeric structures	0.999999999972049	-2.79510661241277e-11	60	0	0	148	10287
R-HSA-5676590	NIK-->noncanonical NF-kB signaling	0.999999999972049	-2.79510661241277e-11	60	0	0	148	10287
R-HSA-6784531	tRNA processing in the nucleus	0.999999999972049	-2.79510661241277e-11	60	0	0	148	10287
R-HSA-5387390	Hh mutants abrogate ligand secretion	0.999999999972049	-2.79510661241277e-11	60	0	0	148	10287
R-HSA-389957	Prefoldin mediated transfer of substrate  to CCT/TriC	0.999999999972952	-2.70476575705687e-11	29	0	0	148	10287
R-HSA-445989	TAK1 activates NFkB by phosphorylation and activation of IKKs complex	0.999999999972952	-2.70476575705687e-11	29	0	0	148	10287
R-HSA-164952	The role of Nef in HIV-1 replication and disease pathogenesis	0.999999999972952	-2.70476575705687e-11	29	0	0	148	10287
R-HSA-5654732	Negative regulation of FGFR3 signaling	0.999999999972952	-2.70476575705687e-11	29	0	0	148	10287
R-HSA-5601884	PIWI-interacting RNA (piRNA) biogenesis	0.999999999972952	-2.70476575705687e-11	29	0	0	148	10287
R-HSA-390918	Peroxisomal lipid metabolism	0.999999999972952	-2.70476575705687e-11	29	0	0	148	10287
R-HSA-5654733	Negative regulation of FGFR4 signaling	0.999999999974111	-2.58893670352254e-11	31	0	0	148	10287
R-HSA-70614	Amino acid synthesis and interconversion (transamination)	0.999999999974111	-2.58893670352254e-11	31	0	0	148	10287
R-HSA-1296065	Inwardly rectifying K+ channels	0.999999999974111	-2.58893670352254e-11	31	0	0	148	10287
R-HSA-352230	Amino acid transport across the plasma membrane	0.999999999974111	-2.58893670352254e-11	31	0	0	148	10287
R-HSA-168333	NEP/NS2 Interacts with the Cellular Export Machinery	0.999999999974111	-2.58893670352254e-11	31	0	0	148	10287
R-HSA-450282	MAPK targets/ Nuclear events mediated by MAP kinases	0.999999999974111	-2.58893670352254e-11	31	0	0	148	10287
R-HSA-2129379	Molecules associated with elastic fibres	0.999999999974111	-2.58893670352254e-11	31	0	0	148	10287
R-HSA-73772	RNA Polymerase I Promoter Escape	0.999999999974111	-2.58893670352254e-11	31	0	0	148	10287
R-HSA-170822	Regulation of Glucokinase by Glucokinase Regulatory Protein	0.999999999974111	-2.58893670352254e-11	31	0	0	148	10287
R-HSA-418990	Adherens junctions interactions	0.999999999974111	-2.58893670352254e-11	31	0	0	148	10287
R-HSA-5654687	Downstream signaling of activated FGFR1	0.999999999974111	-2.58893670352254e-11	31	0	0	148	10287
R-HSA-8875878	MET promotes cell motility	0.999999999974111	-2.58893670352254e-11	31	0	0	148	10287
R-HSA-2022928	HS-GAG biosynthesis	0.999999999974111	-2.58893670352254e-11	31	0	0	148	10287
R-HSA-180786	Extension of Telomeres	0.999999999974111	-2.58893670352254e-11	31	0	0	148	10287
R-HSA-168271	Transport of Ribonucleoproteins into the Host Nucleus	0.999999999974111	-2.58893670352254e-11	31	0	0	148	10287
R-HSA-1839124	FGFR1 mutant receptor activation	0.999999999974111	-2.58893670352254e-11	31	0	0	148	10287
R-HSA-68874	M/G1 Transition	0.999999999975611	-2.43892978774505e-11	86	0	0	148	10287
R-HSA-69002	DNA Replication Pre-Initiation	0.999999999975611	-2.43892978774505e-11	86	0	0	148	10287
R-HSA-5654736	Signaling by FGFR1	0.999999999977666	-2.23342462875746e-11	50	0	0	148	10287
R-HSA-73893	DNA Damage Bypass	0.999999999977666	-2.23342462875746e-11	50	0	0	148	10287
R-HSA-73887	Death Receptor Signalling	0.999999999977666	-2.23342462875746e-11	50	0	0	148	10287
R-HSA-5602680	MyD88 deficiency (TLR5)	0.999999999979945	-2.00544777881048e-11	3	0	0	148	10287
R-HSA-265473	Trafficking of dietary sterols	0.999999999979945	-2.00544777881048e-11	3	0	0	148	10287
R-HSA-5653890	Lactose synthesis	0.999999999979945	-2.00544777881048e-11	3	0	0	148	10287
R-HSA-5627083	RHO GTPases regulate CFTR trafficking	0.999999999979945	-2.00544777881048e-11	3	0	0	148	10287
R-HSA-110330	Recognition and association of DNA glycosylase with site containing an affected purine	0.999999999979945	-2.00544777881048e-11	3	0	0	148	10287
R-HSA-8849472	PTK6 Down-Regulation	0.999999999979945	-2.00544777881048e-11	3	0	0	148	10287
R-HSA-3359463	Defective CUBN causes hereditary megaloblastic anemia 1	0.999999999979945	-2.00544777881048e-11	3	0	0	148	10287
R-HSA-5624958	ARL13B-mediated ciliary trafficking of INPP5E	0.999999999979945	-2.00544777881048e-11	3	0	0	148	10287
R-HSA-1368071	NR1D1 (REV-ERBA) represses gene expression	0.999999999979945	-2.00544777881048e-11	3	0	0	148	10287
R-HSA-964827	Progressive trimming of alpha-1,2-linked mannose residues from Man9/8/7GlcNAc2 to produce Man5GlcNAc2	0.999999999979945	-2.00544777881048e-11	3	0	0	148	10287
R-HSA-77108	Utilization of Ketone Bodies	0.999999999979945	-2.00544777881048e-11	3	0	0	148	10287
R-HSA-191650	Regulation of gap junction activity	0.999999999979945	-2.00544777881048e-11	3	0	0	148	10287
R-HSA-77285	Beta oxidation of myristoyl-CoA to lauroyl-CoA	0.999999999979945	-2.00544777881048e-11	3	0	0	148	10287
R-HSA-191647	c-src mediated regulation of Cx43 function and closure of gap junctions	0.999999999979945	-2.00544777881048e-11	3	0	0	148	10287
R-HSA-111458	Formation of apoptosome	0.999999999979945	-2.00544777881048e-11	3	0	0	148	10287
R-HSA-1299308	Tandem of pore domain in a weak inwardly rectifying K+ channels (TWIK)	0.999999999979945	-2.00544777881048e-11	3	0	0	148	10287
R-HSA-8853336	Signaling by plasma membrane FGFR1 fusions	0.999999999979945	-2.00544777881048e-11	3	0	0	148	10287
R-HSA-379397	Enzymatic degradation of dopamine by COMT	0.999999999979945	-2.00544777881048e-11	3	0	0	148	10287
R-HSA-73843	5-Phosphoribose 1-diphosphate biosynthesis	0.999999999979945	-2.00544777881048e-11	3	0	0	148	10287
R-HSA-163282	Mitochondrial transcription initiation	0.999999999979945	-2.00544777881048e-11	3	0	0	148	10287
R-HSA-5658034	HHAT G278V abrogates palmitoylation of Hh-Np	0.999999999979945	-2.00544777881048e-11	3	0	0	148	10287
R-HSA-193681	Ceramide signalling	0.999999999979945	-2.00544777881048e-11	3	0	0	148	10287
R-HSA-428359	Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA	0.999999999979945	-2.00544777881048e-11	3	0	0	148	10287
R-HSA-3304347	Loss of Function of SMAD4 in Cancer	0.999999999979945	-2.00544777881048e-11	3	0	0	148	10287
R-HSA-198745	Signalling to STAT3	0.999999999979945	-2.00544777881048e-11	3	0	0	148	10287
R-HSA-2395516	Electron transport from NADPH to Ferredoxin	0.999999999979945	-2.00544777881048e-11	3	0	0	148	10287
R-HSA-844455	The NLRP1 inflammasome	0.999999999979945	-2.00544777881048e-11	3	0	0	148	10287
R-HSA-177539	Autointegration results in viral DNA circles	0.999999999979945	-2.00544777881048e-11	3	0	0	148	10287
R-HSA-77305	Beta oxidation of palmitoyl-CoA to myristoyl-CoA	0.999999999979945	-2.00544777881048e-11	3	0	0	148	10287
R-HSA-8875791	MET activates STAT3	0.999999999979945	-2.00544777881048e-11	3	0	0	148	10287
R-HSA-111446	Activation of BIM and translocation to mitochondria	0.999999999979945	-2.00544777881048e-11	3	0	0	148	10287
R-HSA-5357572	Lysosomal glycogen catabolism	0.999999999979945	-2.00544777881048e-11	3	0	0	148	10287
R-HSA-190704	Oligomerization of connexins into connexons	0.999999999979945	-2.00544777881048e-11	3	0	0	148	10287
R-HSA-3359462	Defective AMN causes hereditary megaloblastic anemia 1	0.999999999979945	-2.00544777881048e-11	3	0	0	148	10287
R-HSA-350864	Regulation of thyroid hormone activity	0.999999999979945	-2.00544777881048e-11	3	0	0	148	10287
R-HSA-110331	Cleavage of the damaged purine	0.999999999979945	-2.00544777881048e-11	3	0	0	148	10287
R-HSA-1299503	TWIK related potassium channel (TREK)	0.999999999979945	-2.00544777881048e-11	3	0	0	148	10287
R-HSA-3249367	STAT6-mediated induction of chemokines	0.999999999979945	-2.00544777881048e-11	3	0	0	148	10287
R-HSA-352238	Breakdown of the nuclear lamina	0.999999999979945	-2.00544777881048e-11	3	0	0	148	10287
R-HSA-173599	Formation of the active cofactor, UDP-glucuronate	0.999999999979945	-2.00544777881048e-11	3	0	0	148	10287
R-HSA-5339700	TCF7L2 mutants don't bind CTBP	0.999999999979945	-2.00544777881048e-11	3	0	0	148	10287
R-HSA-1296067	Potassium transport channels	0.999999999979945	-2.00544777881048e-11	3	0	0	148	10287
R-HSA-392023	Adrenaline signalling through Alpha-2 adrenergic receptor	0.999999999979945	-2.00544777881048e-11	3	0	0	148	10287
R-HSA-6806664	Metabolism of vitamin K	0.999999999979945	-2.00544777881048e-11	3	0	0	148	10287
R-HSA-2892245	POU5F1 (OCT4), SOX2, NANOG repress genes related to differentiation	0.999999999979945	-2.00544777881048e-11	3	0	0	148	10287
R-HSA-351200	Interconversion of polyamines	0.999999999979945	-2.00544777881048e-11	3	0	0	148	10287
R-HSA-977442	GABA A (rho) receptor activation	0.999999999979945	-2.00544777881048e-11	3	0	0	148	10287
R-HSA-180897	Vpr-mediated induction of apoptosis by mitochondrial outer membrane permeabilization	0.999999999979945	-2.00544777881048e-11	3	0	0	148	10287
R-HSA-175567	Integration of viral DNA into host genomic DNA	0.999999999979945	-2.00544777881048e-11	3	0	0	148	10287
R-HSA-190374	FGFR1c and Klotho ligand binding and activation	0.999999999979945	-2.00544777881048e-11	3	0	0	148	10287
R-HSA-380615	Serotonin clearance from the synaptic cleft	0.999999999979945	-2.00544777881048e-11	3	0	0	148	10287
R-HSA-5250958	Toxicity of botulinum toxin type B (BoNT/B)	0.999999999979945	-2.00544777881048e-11	3	0	0	148	10287
R-HSA-5688031	Defective pro-SFTPB causes pulmonary surfactant metabolism dysfunction 1 (SMDP1) and respiratory distress syndrome (RDS)	0.999999999979945	-2.00544777881048e-11	3	0	0	148	10287
R-HSA-3296197	Hydroxycarboxylic acid-binding receptors	0.999999999979945	-2.00544777881048e-11	3	0	0	148	10287
R-HSA-217271	FMO oxidises nucleophiles	0.999999999979945	-2.00544777881048e-11	3	0	0	148	10287
R-HSA-379398	Enzymatic degradation of Dopamine by monoamine oxidase	0.999999999979945	-2.00544777881048e-11	3	0	0	148	10287
R-HSA-5602571	TRAF3 deficiency - HSE	0.999999999979945	-2.00544777881048e-11	3	0	0	148	10287
R-HSA-964975	Vitamins B6 activation to pyridoxal phosphate	0.999999999979945	-2.00544777881048e-11	3	0	0	148	10287
R-HSA-139910	Activation of BMF and translocation to mitochondria	0.999999999979945	-2.00544777881048e-11	3	0	0	148	10287
R-HSA-1483248	Synthesis of PIPs at the ER membrane	0.999999999979945	-2.00544777881048e-11	3	0	0	148	10287
R-HSA-427589	Type II Na+/Pi cotransporters	0.999999999979945	-2.00544777881048e-11	3	0	0	148	10287
R-HSA-3311021	SMAD4 MH2 Domain Mutants in Cancer	0.999999999979945	-2.00544777881048e-11	3	0	0	148	10287
R-HSA-5250992	Toxicity of botulinum toxin type E (BoNT/E)	0.999999999979945	-2.00544777881048e-11	3	0	0	148	10287
R-HSA-73927	Depurination	0.999999999979945	-2.00544777881048e-11	3	0	0	148	10287
R-HSA-170145	Phosphorylation of proteins involved in the G2/M transition by Cyclin A:Cdc2 complexes	0.999999999979945	-2.00544777881048e-11	3	0	0	148	10287
R-HSA-444411	Rhesus glycoproteins mediate ammonium transport.	0.999999999979945	-2.00544777881048e-11	3	0	0	148	10287
R-HSA-190827	Transport of connexins along the secretory pathway	0.999999999979945	-2.00544777881048e-11	3	0	0	148	10287
R-HSA-5635851	GLI proteins bind promoters of Hh responsive genes to promote transcription	0.999999999979945	-2.00544777881048e-11	3	0	0	148	10287
R-HSA-844615	The AIM2 inflammasome	0.999999999979945	-2.00544777881048e-11	3	0	0	148	10287
R-HSA-1234162	Oxygen-dependent asparagine hydroxylation of Hypoxia-inducible Factor Alpha	0.999999999979945	-2.00544777881048e-11	3	0	0	148	10287
R-HSA-5250989	Toxicity of botulinum toxin type G (BoNT/G)	0.999999999979945	-2.00544777881048e-11	3	0	0	148	10287
R-HSA-880009	Interconversion of 2-oxoglutarate and 2-hydroxyglutarate	0.999999999979945	-2.00544777881048e-11	3	0	0	148	10287
R-HSA-5250971	Toxicity of botulinum toxin type C (BoNT/C)	0.999999999979945	-2.00544777881048e-11	3	0	0	148	10287
R-HSA-165181	Inhibition of TSC complex formation by PKB	0.999999999979945	-2.00544777881048e-11	3	0	0	148	10287
R-HSA-1307965	betaKlotho-mediated ligand binding	0.999999999979945	-2.00544777881048e-11	3	0	0	148	10287
R-HSA-162699	Synthesis of dolichyl-phosphate mannose	0.999999999979945	-2.00544777881048e-11	3	0	0	148	10287
R-HSA-446193	Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein	0.999999999980433	-1.95665444375252e-11	78	0	0	148	10287
R-HSA-380287	Centrosome maturation	0.999999999980475	-1.9525331775395e-11	82	0	0	148	10287
R-HSA-380270	Recruitment of mitotic centrosome proteins and complexes	0.999999999980475	-1.9525331775395e-11	82	0	0	148	10287
R-HSA-157579	Telomere Maintenance	0.999999999980475	-1.9525331775395e-11	82	0	0	148	10287
R-HSA-5628897	TP53 Regulates Metabolic Genes	0.999999999980475	-1.9525331775395e-11	82	0	0	148	10287
R-HSA-69190	DNA strand elongation	0.999999999980484	-1.95162823805343e-11	32	0	0	148	10287
R-HSA-451326	Activation of Kainate Receptors upon glutamate binding	0.999999999980484	-1.95162823805343e-11	32	0	0	148	10287
R-HSA-4641262	Disassembly of the destruction complex and recruitment of AXIN to the membrane	0.999999999980484	-1.95162823805343e-11	32	0	0	148	10287
R-HSA-196071	Metabolism of steroid hormones	0.999999999980484	-1.95162823805343e-11	32	0	0	148	10287
R-HSA-68962	Activation of the pre-replicative complex	0.999999999980484	-1.95162823805343e-11	32	0	0	148	10287
R-HSA-168274	Export of Viral Ribonucleoproteins from Nucleus	0.999999999980484	-1.95162823805343e-11	32	0	0	148	10287
R-HSA-456926	Thrombin signalling through proteinase activated receptors (PARs)	0.999999999980484	-1.95162823805343e-11	32	0	0	148	10287
R-HSA-1592389	Activation of Matrix Metalloproteinases	0.999999999980484	-1.95162823805343e-11	32	0	0	148	10287
R-HSA-2559585	Oncogene Induced Senescence	0.999999999980484	-1.95162823805343e-11	32	0	0	148	10287
R-HSA-73863	RNA Polymerase I Transcription Termination	0.999999999980484	-1.95162823805343e-11	32	0	0	148	10287
R-HSA-165054	Rev-mediated nuclear export of HIV RNA	0.999999999980703	-1.92974119497471e-11	34	0	0	148	10287
R-HSA-113510	E2F mediated regulation of DNA replication	0.999999999980703	-1.92974119497471e-11	34	0	0	148	10287
R-HSA-5654727	Negative regulation of FGFR2 signaling	0.999999999980703	-1.92974119497471e-11	34	0	0	148	10287
R-HSA-5656169	Termination of translesion DNA synthesis	0.999999999980703	-1.92974119497471e-11	34	0	0	148	10287
R-HSA-192105	Synthesis of bile acids and bile salts	0.999999999980703	-1.92974119497471e-11	34	0	0	148	10287
R-HSA-5694530	Cargo concentration in the ER	0.999999999980703	-1.92974119497471e-11	34	0	0	148	10287
R-HSA-389958	Cooperation of Prefoldin and TriC/CCT  in actin and tubulin folding	0.999999999980703	-1.92974119497471e-11	34	0	0	148	10287
R-HSA-2173789	TGF-beta receptor signaling activates SMADs	0.999999999980703	-1.92974119497471e-11	34	0	0	148	10287
R-HSA-1483166	Synthesis of PA	0.999999999980703	-1.92974119497471e-11	34	0	0	148	10287
R-HSA-159227	Transport of the SLBP independent Mature mRNA	0.999999999980703	-1.92974119497471e-11	34	0	0	148	10287
R-HSA-2559584	Formation of Senescence-Associated Heterochromatin Foci (SAHF)	0.999999999981501	-1.84993961363748e-11	16	0	0	148	10287
R-HSA-110312	Translesion synthesis by REV1	0.999999999981501	-1.84993961363748e-11	16	0	0	148	10287
R-HSA-1963640	GRB2 events in ERBB2 signaling	0.999999999981501	-1.84993961363748e-11	16	0	0	148	10287
R-HSA-5684264	MAP3K8 (TPL2)-dependent MAPK1/3 activation	0.999999999981501	-1.84993961363748e-11	16	0	0	148	10287
R-HSA-1170546	Prolactin receptor signaling	0.999999999981501	-1.84993961363748e-11	16	0	0	148	10287
R-HSA-354194	GRB2:SOS provides linkage to MAPK signaling for Integrins	0.999999999981501	-1.84993961363748e-11	16	0	0	148	10287
R-HSA-8866910	TFAP2 (AP-2) family regulates transcription of growth factors and their receptors	0.999999999981501	-1.84993961363748e-11	16	0	0	148	10287
R-HSA-1295596	Spry regulation of FGF signaling	0.999999999981501	-1.84993961363748e-11	16	0	0	148	10287
R-HSA-162710	Synthesis of glycosylphosphatidylinositol (GPI)	0.999999999981501	-1.84993961363748e-11	16	0	0	148	10287
R-HSA-5218859	Regulated Necrosis	0.999999999981501	-1.84993961363748e-11	16	0	0	148	10287
R-HSA-392517	Rap1 signalling	0.999999999981501	-1.84993961363748e-11	16	0	0	148	10287
R-HSA-418038	Nucleotide-like (purinergic) receptors	0.999999999981501	-1.84993961363748e-11	16	0	0	148	10287
R-HSA-159418	Recycling of bile acids and salts	0.999999999981501	-1.84993961363748e-11	16	0	0	148	10287
R-HSA-549132	Organic cation/anion/zwitterion transport	0.999999999981501	-1.84993961363748e-11	16	0	0	148	10287
R-HSA-5637812	Signaling by EGFRvIII in Cancer	0.999999999981501	-1.84993961363748e-11	16	0	0	148	10287
R-HSA-163210	Formation of ATP by chemiosmotic coupling	0.999999999981501	-1.84993961363748e-11	16	0	0	148	10287
R-HSA-918233	TRAF3-dependent IRF activation pathway	0.999999999981501	-1.84993961363748e-11	16	0	0	148	10287
R-HSA-372708	p130Cas linkage to MAPK signaling for integrins	0.999999999981501	-1.84993961363748e-11	16	0	0	148	10287
R-HSA-1834941	STING mediated induction of host immune responses	0.999999999981501	-1.84993961363748e-11	16	0	0	148	10287
R-HSA-5637810	Constitutive Signaling by EGFRvIII	0.999999999981501	-1.84993961363748e-11	16	0	0	148	10287
R-HSA-5213460	RIPK1-mediated regulated necrosis	0.999999999981501	-1.84993961363748e-11	16	0	0	148	10287
R-HSA-190242	FGFR1 ligand binding and activation	0.999999999981501	-1.84993961363748e-11	16	0	0	148	10287
R-HSA-975163	IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation	0.999999999981501	-1.84993961363748e-11	16	0	0	148	10287
R-HSA-5654219	Phospholipase C-mediated cascade: FGFR1	0.999999999981501	-1.84993961363748e-11	16	0	0	148	10287
R-HSA-1963642	PI3K events in ERBB2 signaling	0.999999999981501	-1.84993961363748e-11	16	0	0	148	10287
R-HSA-4615885	SUMOylation of DNA replication proteins	0.999999999981501	-1.84986846786079e-11	46	0	0	148	10287
R-HSA-1660662	Glycosphingolipid metabolism	0.999999999981501	-1.84986846786079e-11	46	0	0	148	10287
R-HSA-749476	RNA Polymerase III Abortive And Retractive Initiation	0.999999999982077	-1.79232386435946e-11	41	0	0	148	10287
R-HSA-5696400	Dual Incision in GG-NER	0.999999999982077	-1.79232386435946e-11	41	0	0	148	10287
R-HSA-74158	RNA Polymerase III Transcription	0.999999999982077	-1.79232386435946e-11	41	0	0	148	10287
R-HSA-110313	Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template	0.999999999982077	-1.79232386435946e-11	41	0	0	148	10287
R-HSA-5654743	Signaling by FGFR4	0.999999999982077	-1.79232386435946e-11	41	0	0	148	10287
R-HSA-3560782	Diseases associated with glycosaminoglycan metabolism	0.999999999983594	-1.64061882508983e-11	26	0	0	148	10287
R-HSA-379716	Cytosolic tRNA aminoacylation	0.999999999983594	-1.64061882508983e-11	26	0	0	148	10287
R-HSA-1474165	Reproduction	0.999999999983594	-1.64061882508983e-11	26	0	0	148	10287
R-HSA-73848	Pyrimidine metabolism	0.999999999983594	-1.64061882508983e-11	26	0	0	148	10287
R-HSA-975298	Ligand-gated ion channel transport	0.999999999983594	-1.64061882508983e-11	26	0	0	148	10287
R-HSA-975576	N-glycan antennae elongation in the medial/trans-Golgi	0.999999999983594	-1.64061882508983e-11	26	0	0	148	10287
R-HSA-389960	Formation of tubulin folding intermediates by CCT/TriC	0.999999999983594	-1.64061882508983e-11	26	0	0	148	10287
R-HSA-210991	Basigin interactions	0.999999999983594	-1.64061882508983e-11	26	0	0	148	10287
R-HSA-5357956	TNFR1-induced NFkappaB signaling pathway	0.999999999983594	-1.64061882508983e-11	26	0	0	148	10287
R-HSA-1187000	Fertilization	0.999999999983594	-1.64061882508983e-11	26	0	0	148	10287
R-HSA-5358565	Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)	0.99999999998411	-1.58900115497653e-11	14	0	0	148	10287
R-HSA-162594	Early Phase of HIV Life Cycle	0.99999999998411	-1.58900115497653e-11	14	0	0	148	10287
R-HSA-1679131	Trafficking and processing of endosomal TLR	0.99999999998411	-1.58900115497653e-11	14	0	0	148	10287
R-HSA-1250347	SHC1 events in ERBB4 signaling	0.99999999998411	-1.58900115497653e-11	14	0	0	148	10287
R-HSA-209560	NF-kB is activated and signals survival	0.99999999998411	-1.58900115497653e-11	14	0	0	148	10287
R-HSA-162658	Golgi Cisternae Pericentriolar Stack Reorganization	0.99999999998411	-1.58900115497653e-11	14	0	0	148	10287
R-HSA-181431	Acetylcholine Binding And Downstream Events	0.99999999998411	-1.58900115497653e-11	14	0	0	148	10287
R-HSA-5467340	AXIN missense mutants destabilize the destruction complex	0.99999999998411	-1.58900115497653e-11	14	0	0	148	10287
R-HSA-428790	Facilitative Na+-independent glucose transporters	0.99999999998411	-1.58900115497653e-11	14	0	0	148	10287
R-HSA-629602	Activation of Nicotinic Acetylcholine Receptors	0.99999999998411	-1.58900115497653e-11	14	0	0	148	10287
R-HSA-174403	Glutathione synthesis and recycling	0.99999999998411	-1.58900115497653e-11	14	0	0	148	10287
R-HSA-428540	Activation of Rac	0.99999999998411	-1.58900115497653e-11	14	0	0	148	10287
R-HSA-209952	Peptide hormone biosynthesis	0.99999999998411	-1.58900115497653e-11	14	0	0	148	10287
R-HSA-2024101	CS/DS degradation	0.99999999998411	-1.58900115497653e-11	14	0	0	148	10287
R-HSA-6803205	TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain	0.99999999998411	-1.58900115497653e-11	14	0	0	148	10287
R-HSA-418359	Reduction of cytosolic Ca++ levels	0.99999999998411	-1.58900115497653e-11	14	0	0	148	10287
R-HSA-4839744	truncated APC mutants destabilize the destruction complex	0.99999999998411	-1.58900115497653e-11	14	0	0	148	10287
R-HSA-69166	Removal of the Flap Intermediate	0.99999999998411	-1.58900115497653e-11	14	0	0	148	10287
R-HSA-5358606	Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)	0.99999999998411	-1.58900115497653e-11	14	0	0	148	10287
R-HSA-5467348	Truncations of AMER1 destabilize the destruction complex	0.99999999998411	-1.58900115497653e-11	14	0	0	148	10287
R-HSA-193775	Synthesis of bile acids and bile salts via 24-hydroxycholesterol	0.99999999998411	-1.58900115497653e-11	14	0	0	148	10287
R-HSA-209543	p75NTR recruits signalling complexes	0.99999999998411	-1.58900115497653e-11	14	0	0	148	10287
R-HSA-4839735	AXIN mutants destabilize the destruction complex, activating WNT signaling	0.99999999998411	-1.58900115497653e-11	14	0	0	148	10287
R-HSA-622327	Postsynaptic nicotinic acetylcholine receptors	0.99999999998411	-1.58900115497653e-11	14	0	0	148	10287
R-HSA-190322	FGFR4 ligand binding and activation	0.99999999998411	-1.58900115497653e-11	14	0	0	148	10287
R-HSA-1660516	Synthesis of PIPs at the early endosome membrane	0.99999999998411	-1.58900115497653e-11	14	0	0	148	10287
R-HSA-5467337	APC truncation mutants have impaired AXIN binding	0.99999999998411	-1.58900115497653e-11	14	0	0	148	10287
R-HSA-174411	Polymerase switching on the C-strand of the telomere	0.99999999998411	-1.58900115497653e-11	14	0	0	148	10287
R-HSA-419408	Lysosphingolipid and LPA receptors	0.99999999998411	-1.58900115497653e-11	14	0	0	148	10287
R-HSA-6804759	Regulation of TP53 Activity through Association with Co-factors	0.99999999998411	-1.58900115497653e-11	14	0	0	148	10287
R-HSA-5675482	Regulation of necroptotic cell death	0.99999999998411	-1.58900115497653e-11	14	0	0	148	10287
R-HSA-1483213	Synthesis of PE	0.99999999998411	-1.58900115497653e-11	14	0	0	148	10287
R-HSA-69091	Polymerase switching	0.99999999998411	-1.58900115497653e-11	14	0	0	148	10287
R-HSA-177504	Retrograde neurotrophin signalling	0.99999999998411	-1.58900115497653e-11	14	0	0	148	10287
R-HSA-4839748	AMER1 mutants destabilize the destruction complex	0.99999999998411	-1.58900115497653e-11	14	0	0	148	10287
R-HSA-69109	Leading Strand Synthesis	0.99999999998411	-1.58900115497653e-11	14	0	0	148	10287
R-HSA-72764	Eukaryotic Translation Termination	0.999999999984759	-1.52411367210292e-11	96	0	0	148	10287
R-HSA-156842	Eukaryotic Translation Elongation	0.999999999984759	-1.52411367210292e-11	96	0	0	148	10287
R-HSA-176407	Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase	0.999999999984836	-1.51643955864772e-11	19	0	0	148	10287
R-HSA-202430	Translocation of ZAP-70 to Immunological synapse	0.999999999984836	-1.51643955864772e-11	19	0	0	148	10287
R-HSA-3560801	Defective B3GAT3 causes JDSSDHD	0.999999999984836	-1.51643955864772e-11	19	0	0	148	10287
R-HSA-176412	Phosphorylation of the APC/C	0.999999999984836	-1.51643955864772e-11	19	0	0	148	10287
R-HSA-450321	JNK (c-Jun kinases) phosphorylation and  activation mediated by activated human TAK1	0.999999999984836	-1.51643955864772e-11	19	0	0	148	10287
R-HSA-5576886	Phase 4 - resting membrane potential	0.999999999984836	-1.51643955864772e-11	19	0	0	148	10287
R-HSA-392851	Prostacyclin signalling through prostacyclin receptor	0.999999999984836	-1.51643955864772e-11	19	0	0	148	10287
R-HSA-110320	Translesion Synthesis by POLH	0.999999999984836	-1.51643955864772e-11	19	0	0	148	10287
R-HSA-3560783	Defective B4GALT7 causes EDS, progeroid type	0.999999999984836	-1.51643955864772e-11	19	0	0	148	10287
R-HSA-190861	Gap junction assembly	0.999999999984836	-1.51643955864772e-11	19	0	0	148	10287
R-HSA-4420332	Defective B3GALT6 causes EDSP2 and SEMDJL1	0.999999999984836	-1.51643955864772e-11	19	0	0	148	10287
R-HSA-422085	Synthesis, secretion, and deacylation of Ghrelin	0.999999999984836	-1.51643955864772e-11	19	0	0	148	10287
R-HSA-1660514	Synthesis of PIPs at the Golgi membrane	0.999999999984836	-1.51643955864772e-11	19	0	0	148	10287
R-HSA-71403	Citric acid cycle (TCA cycle)	0.999999999984836	-1.51643955864772e-11	19	0	0	148	10287
R-HSA-6804114	TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest	0.999999999984836	-1.51643955864772e-11	19	0	0	148	10287
R-HSA-156584	Cytosolic sulfonation of small molecules	0.999999999984836	-1.51643955864772e-11	19	0	0	148	10287
R-HSA-442660	Na+/Cl- dependent neurotransmitter transporters	0.999999999984836	-1.51643955864772e-11	19	0	0	148	10287
R-HSA-450604	KSRP (KHSRP) binds and destabilizes mRNA	0.999999999984836	-1.51643955864772e-11	19	0	0	148	10287
R-HSA-5223345	Miscellaneous transport and binding events	0.999999999984836	-1.51643955864772e-11	19	0	0	148	10287
R-HSA-8876725	Protein methylation	0.999999999984836	-1.51643955864772e-11	19	0	0	148	10287
R-HSA-5250968	Toxicity of botulinum toxin type A (BoNT/A)	0.999999999985284	-1.47157376838084e-11	4	0	0	148	10287
R-HSA-69560	Transcriptional activation of p53 responsive genes	0.999999999985284	-1.47157376838084e-11	4	0	0	148	10287
R-HSA-5083630	Defective LFNG causes SCDO3	0.999999999985284	-1.47157376838084e-11	4	0	0	148	10287
R-HSA-5221030	TET1,2,3 and TDG demethylate DNA	0.999999999985284	-1.47157376838084e-11	4	0	0	148	10287
R-HSA-447115	Interleukin-12 signaling	0.999999999985284	-1.47157376838084e-11	4	0	0	148	10287
R-HSA-8847453	Synthesis of PIPs in the nucleus	0.999999999985284	-1.47157376838084e-11	4	0	0	148	10287
R-HSA-8849474	PTK6 Activates STAT3	0.999999999985284	-1.47157376838084e-11	4	0	0	148	10287
R-HSA-428542	Regulation of Commissural axon pathfinding by Slit and Robo	0.999999999985284	-1.47157376838084e-11	4	0	0	148	10287
R-HSA-173736	Alternative complement activation	0.999999999985284	-1.47157376838084e-11	4	0	0	148	10287
R-HSA-2408550	Metabolism of ingested H2SeO4 and H2SeO3 into H2Se	0.999999999985284	-1.47157376838084e-11	4	0	0	148	10287
R-HSA-204626	Hypusine synthesis from eIF5A-lysine	0.999999999985284	-1.47157376838084e-11	4	0	0	148	10287
R-HSA-176034	Interactions of Tat with host cellular proteins	0.999999999985284	-1.47157376838084e-11	4	0	0	148	10287
R-HSA-4551638	SUMOylation of chromatin organization proteins	0.999999999985284	-1.47157376838084e-11	4	0	0	148	10287
R-HSA-1296061	HCN channels	0.999999999985284	-1.47157376838084e-11	4	0	0	148	10287
R-HSA-210455	Astrocytic Glutamate-Glutamine Uptake And Metabolism	0.999999999985284	-1.47157376838084e-11	4	0	0	148	10287
R-HSA-379401	Dopamine clearance from the synaptic cleft	0.999999999985284	-1.47157376838084e-11	4	0	0	148	10287
R-HSA-1296053	Classical Kir channels	0.999999999985284	-1.47157376838084e-11	4	0	0	148	10287
R-HSA-8848584	Wax biosynthesis	0.999999999985284	-1.47157376838084e-11	4	0	0	148	10287
R-HSA-69200	Phosphorylation of proteins involved in G1/S transition by active Cyclin E:Cdk2 complexes	0.999999999985284	-1.47157376838084e-11	4	0	0	148	10287
R-HSA-194306	Neurophilin interactions with VEGF and VEGFR	0.999999999985284	-1.47157376838084e-11	4	0	0	148	10287
R-HSA-6783984	Glycine degradation	0.999999999985284	-1.47157376838084e-11	4	0	0	148	10287
R-HSA-69895	Transcriptional  activation of  cell cycle inhibitor p21	0.999999999985284	-1.47157376838084e-11	4	0	0	148	10287
R-HSA-2473224	Antagonism of Activin by Follistatin	0.999999999985284	-1.47157376838084e-11	4	0	0	148	10287
R-HSA-5603037	IRAK4 deficiency (TLR5)	0.999999999985284	-1.47157376838084e-11	4	0	0	148	10287
R-HSA-888593	Reuptake of GABA	0.999999999985284	-1.47157376838084e-11	4	0	0	148	10287
R-HSA-211163	AKT-mediated inactivation of FOXO1A	0.999999999985284	-1.47157376838084e-11	4	0	0	148	10287
R-HSA-427975	Proton/oligopeptide cotransporters	0.999999999985284	-1.47157376838084e-11	4	0	0	148	10287
R-HSA-6807062	Cholesterol biosynthesis via lathosterol	0.999999999985284	-1.47157376838084e-11	4	0	0	148	10287
R-HSA-5579026	Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)	0.999999999985284	-1.47157376838084e-11	4	0	0	148	10287
R-HSA-1855191	Synthesis of IPs in the nucleus	0.999999999985284	-1.47157376838084e-11	4	0	0	148	10287
R-HSA-1369007	Mitochondrial ABC transporters	0.999999999985284	-1.47157376838084e-11	4	0	0	148	10287
R-HSA-3000497	Scavenging by Class H Receptors	0.999999999985284	-1.47157376838084e-11	4	0	0	148	10287
R-HSA-399710	Activation of AMPA receptors	0.999999999985284	-1.47157376838084e-11	4	0	0	148	10287
R-HSA-110381	Resolution of AP sites via the single-nucleotide replacement pathway	0.999999999985284	-1.47157376838084e-11	4	0	0	148	10287
R-HSA-209905	Catecholamine biosynthesis	0.999999999985284	-1.47157376838084e-11	4	0	0	148	10287
R-HSA-209563	Axonal growth stimulation	0.999999999985284	-1.47157376838084e-11	4	0	0	148	10287
R-HSA-417973	Adenosine P1 receptors	0.999999999985284	-1.47157376838084e-11	4	0	0	148	10287
R-HSA-6802953	RAS signaling downstream of NF1 loss-of-function variants	0.999999999985284	-1.47157376838084e-11	4	0	0	148	10287
R-HSA-6807047	Cholesterol biosynthesis via desmosterol	0.999999999985284	-1.47157376838084e-11	4	0	0	148	10287
R-HSA-112126	ALKBH3 mediated reversal of alkylation damage	0.999999999985284	-1.47157376838084e-11	4	0	0	148	10287
R-HSA-3878781	Glycogen storage disease type IV (GBE1)	0.999999999985284	-1.47157376838084e-11	4	0	0	148	10287
R-HSA-140179	Amine Oxidase reactions	0.999999999985284	-1.47157376838084e-11	4	0	0	148	10287
R-HSA-428776	Class II GLUTs	0.999999999985284	-1.47157376838084e-11	4	0	0	148	10287
R-HSA-5619099	Defective AVP causes neurohypophyseal diabetes insipidus (NDI)	0.999999999985284	-1.47157376838084e-11	4	0	0	148	10287
R-HSA-75108	Activation, myristolyation of BID and translocation to mitochondria	0.999999999985284	-1.47157376838084e-11	4	0	0	148	10287
R-HSA-173107	Binding and entry of HIV virion	0.999999999985284	-1.47157376838084e-11	4	0	0	148	10287
R-HSA-75944	Transcription from mitochondrial promoters	0.999999999985284	-1.47157376838084e-11	4	0	0	148	10287
R-HSA-1251932	PLCG1 events in ERBB2 signaling	0.999999999985284	-1.47157376838084e-11	4	0	0	148	10287
R-HSA-442745	Activation of CaMK IV	0.999999999985284	-1.47157376838084e-11	4	0	0	148	10287
R-HSA-8935690	Miscellaneous digestion events	0.999999999985284	-1.47157376838084e-11	4	0	0	148	10287
R-HSA-1296025	ATP sensitive Potassium channels	0.999999999985284	-1.47157376838084e-11	4	0	0	148	10287
R-HSA-8866906	TFAP2 (AP-2) family regulates transcription of other transcription factors	0.999999999985284	-1.47157376838084e-11	4	0	0	148	10287
R-HSA-390650	Histamine receptors	0.999999999985284	-1.47157376838084e-11	4	0	0	148	10287
R-HSA-167060	NGF processing	0.999999999985284	-1.47157376838084e-11	4	0	0	148	10287
R-HSA-112313	Neurotransmitter uptake and Metabolism In Glial Cells	0.999999999985284	-1.47157376838084e-11	4	0	0	148	10287
R-HSA-202427	Phosphorylation of CD3 and TCR zeta chains	0.999999999985295	-1.47047033359847e-11	22	0	0	148	10287
R-HSA-140837	Intrinsic Pathway of Fibrin Clot Formation	0.999999999985295	-1.47047033359847e-11	22	0	0	148	10287
R-HSA-164938	Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters	0.999999999985295	-1.47047033359847e-11	22	0	0	148	10287
R-HSA-203765	eNOS activation and regulation	0.999999999985295	-1.47047033359847e-11	22	0	0	148	10287
R-HSA-77595	Processing of Intronless Pre-mRNAs	0.999999999985295	-1.47047033359847e-11	22	0	0	148	10287
R-HSA-901032	ER Quality Control Compartment (ERQC)	0.999999999985295	-1.47047033359847e-11	22	0	0	148	10287
R-HSA-8853338	Signaling by FGFR3 point mutants in cancer	0.999999999985295	-1.47047033359847e-11	22	0	0	148	10287
R-HSA-69273	Cyclin A/B1 associated events during G2/M transition	0.999999999985295	-1.47047033359847e-11	22	0	0	148	10287
R-HSA-5655332	Signaling by FGFR3 in disease	0.999999999985295	-1.47047033359847e-11	22	0	0	148	10287
R-HSA-373753	Nephrin interactions	0.999999999985295	-1.47047033359847e-11	22	0	0	148	10287
R-HSA-5621575	CD209 (DC-SIGN) signaling	0.999999999985295	-1.47047033359847e-11	22	0	0	148	10287
R-HSA-166208	mTORC1-mediated signalling	0.999999999985295	-1.47047033359847e-11	22	0	0	148	10287
R-HSA-5654712	FRS-mediated FGFR4 signaling	0.999999999985295	-1.47047033359847e-11	22	0	0	148	10287
R-HSA-1482801	Acyl chain remodelling of PS	0.999999999985295	-1.47047033359847e-11	22	0	0	148	10287
R-HSA-389513	CTLA4 inhibitory signaling	0.999999999985295	-1.47047033359847e-11	22	0	0	148	10287
R-HSA-2142691	Synthesis of Leukotrienes (LT) and Eoxins (EX)	0.999999999985295	-1.47047033359847e-11	22	0	0	148	10287
R-HSA-198753	ERK/MAPK targets	0.999999999985295	-1.47047033359847e-11	22	0	0	148	10287
R-HSA-77289	Mitochondrial Fatty Acid Beta-Oxidation	0.999999999985295	-1.47047033359847e-11	22	0	0	148	10287
R-HSA-140875	Common Pathway of Fibrin Clot Formation	0.999999999985295	-1.47047033359847e-11	22	0	0	148	10287
R-HSA-5620916	VxPx cargo-targeting to cilium	0.999999999985295	-1.47047033359847e-11	22	0	0	148	10287
R-HSA-202131	Metabolism of nitric oxide	0.999999999985295	-1.47047033359847e-11	22	0	0	148	10287
R-HSA-5673000	RAF activation	0.999999999986087	-1.39134241840056e-11	25	0	0	148	10287
R-HSA-5674400	Constitutive Signaling by AKT1 E17K in Cancer	0.999999999986087	-1.39134241840056e-11	25	0	0	148	10287
R-HSA-997272	Inhibition  of voltage gated Ca2+ channels via Gbeta/gamma subunits	0.999999999986087	-1.39134241840056e-11	25	0	0	148	10287
R-HSA-1251985	Nuclear signaling by ERBB4	0.999999999986087	-1.39134241840056e-11	25	0	0	148	10287
R-HSA-429947	Deadenylation of mRNA	0.999999999986087	-1.39134241840056e-11	25	0	0	148	10287
R-HSA-1614635	Sulfur amino acid metabolism	0.999999999986087	-1.39134241840056e-11	25	0	0	148	10287
R-HSA-5654700	FRS-mediated FGFR2 signaling	0.999999999986087	-1.39134241840056e-11	25	0	0	148	10287
R-HSA-983170	Antigen Presentation: Folding, assembly and peptide loading of class I MHC	0.999999999986087	-1.39134241840056e-11	25	0	0	148	10287
R-HSA-182971	EGFR downregulation	0.999999999986087	-1.39134241840056e-11	25	0	0	148	10287
R-HSA-977068	Termination of O-glycan biosynthesis	0.999999999986087	-1.39134241840056e-11	25	0	0	148	10287
R-HSA-5696397	Gap-filling DNA repair synthesis and ligation in GG-NER	0.999999999986087	-1.39134241840056e-11	25	0	0	148	10287
R-HSA-198725	Nuclear Events (kinase and transcription factor activation)	0.999999999986087	-1.39134241840056e-11	25	0	0	148	10287
R-HSA-179409	APC-Cdc20 mediated degradation of Nek2A	0.999999999986087	-1.39134241840056e-11	25	0	0	148	10287
R-HSA-1606322	ZBP1(DAI) mediated induction of type I IFNs	0.999999999986087	-1.39134241840056e-11	25	0	0	148	10287
R-HSA-389661	Glyoxylate metabolism and glycine degradation	0.999999999986087	-1.39134241840056e-11	25	0	0	148	10287
R-HSA-1296059	G protein gated Potassium channels	0.999999999986087	-1.39134241840056e-11	25	0	0	148	10287
R-HSA-162588	Budding and maturation of HIV virion	0.999999999986087	-1.39134241840056e-11	25	0	0	148	10287
R-HSA-203927	MicroRNA (miRNA) biogenesis	0.999999999986087	-1.39134241840056e-11	25	0	0	148	10287
R-HSA-3000157	Laminin interactions	0.999999999986087	-1.39134241840056e-11	25	0	0	148	10287
R-HSA-933542	TRAF6 mediated NF-kB activation	0.999999999986087	-1.39134241840056e-11	25	0	0	148	10287
R-HSA-1538133	G0 and Early G1	0.999999999986087	-1.39134241840056e-11	25	0	0	148	10287
R-HSA-3295583	TRP channels	0.999999999986087	-1.39134241840056e-11	25	0	0	148	10287
R-HSA-5654708	Downstream signaling of activated FGFR3	0.999999999986087	-1.39134241840056e-11	25	0	0	148	10287
R-HSA-418592	ADP signalling through P2Y purinoceptor 1	0.999999999986087	-1.39134241840056e-11	25	0	0	148	10287
R-HSA-499943	Synthesis and interconversion of nucleotide di- and triphosphates	0.999999999986087	-1.39134241840056e-11	25	0	0	148	10287
R-HSA-1296041	Activation of G protein gated Potassium channels	0.999999999986087	-1.39134241840056e-11	25	0	0	148	10287
R-HSA-420499	Class C/3 (Metabotropic glutamate/pheromone receptors)	0.99999999998614	-1.38596628351815e-11	39	0	0	148	10287
R-HSA-140877	Formation of Fibrin Clot (Clotting Cascade)	0.99999999998614	-1.38596628351815e-11	39	0	0	148	10287
R-HSA-5696394	DNA Damage Recognition in GG-NER	0.99999999998614	-1.38596628351815e-11	39	0	0	148	10287
R-HSA-69236	G1 Phase	0.99999999998614	-1.38596628351815e-11	39	0	0	148	10287
R-HSA-6802955	Paradoxical activation of RAF signaling by kinase inactive BRAF	0.99999999998614	-1.38596628351815e-11	39	0	0	148	10287
R-HSA-69231	Cyclin D associated events in G1	0.99999999998614	-1.38596628351815e-11	39	0	0	148	10287
R-HSA-6802946	Signaling by moderate kinase activity BRAF mutants	0.99999999998614	-1.38596628351815e-11	39	0	0	148	10287
R-HSA-1296072	Voltage gated Potassium channels	0.999999999986915	-1.3085299141122e-11	44	0	0	148	10287
R-HSA-5668914	Diseases of metabolism	0.999999999986915	-1.3085299141122e-11	44	0	0	148	10287
R-HSA-975634	Retinoid metabolism and transport	0.999999999986915	-1.3085299141122e-11	44	0	0	148	10287
R-HSA-1660661	Sphingolipid de novo biosynthesis	0.999999999986915	-1.3085299141122e-11	44	0	0	148	10287
R-HSA-159231	Transport of Mature mRNA Derived from an Intronless Transcript	0.999999999986915	-1.3085299141122e-11	44	0	0	148	10287
R-HSA-176814	Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins	0.999999999987047	-1.29531046212753e-11	77	0	0	148	10287
R-HSA-69304	Regulation of DNA replication	0.999999999987047	-1.29531046212753e-11	77	0	0	148	10287
R-HSA-2262749	Cellular response to hypoxia	0.999999999987047	-1.29531046212753e-11	77	0	0	148	10287
R-HSA-1234174	Regulation of Hypoxia-inducible Factor (HIF) by oxygen	0.999999999987047	-1.29531046212753e-11	77	0	0	148	10287
R-HSA-427413	NoRC negatively regulates rRNA expression	0.999999999987052	-1.29479599202325e-11	107	0	0	148	10287
R-HSA-425393	Transport of inorganic cations/anions and amino acids/oligopeptides	0.999999999987052	-1.29479599202325e-11	107	0	0	148	10287
R-HSA-1461973	Defensins	0.999999999987599	-1.24011981267025e-11	51	0	0	148	10287
R-HSA-383280	Nuclear Receptor transcription pathway	0.999999999987599	-1.24011981267025e-11	51	0	0	148	10287
R-HSA-211733	Regulation of activated PAK-2p34 by proteasome mediated degradation	0.999999999987599	-1.24011981267025e-11	51	0	0	148	10287
R-HSA-1236978	Cross-presentation of soluble exogenous antigens (endosomes)	0.999999999987599	-1.24011981267025e-11	51	0	0	148	10287
R-HSA-397795	G-protein beta:gamma signalling	0.999999999987599	-1.24011981267025e-11	51	0	0	148	10287
R-HSA-6799198	Complex I biogenesis	0.999999999987599	-1.24011981267025e-11	51	0	0	148	10287
R-HSA-171306	Packaging Of Telomere Ends	0.999999999987599	-1.24011981267025e-11	51	0	0	148	10287
R-HSA-69481	G2/M Checkpoints	0.999999999987626	-1.23738010002376e-11	169	0	0	148	10287
R-HSA-379724	tRNA Aminoacylation	0.9999999999879	-1.21003780338754e-11	45	0	0	148	10287
R-HSA-2151201	Transcriptional activation of mitochondrial biogenesis	0.9999999999879	-1.21003780338754e-11	45	0	0	148	10287
R-HSA-159234	Transport of Mature mRNAs Derived from Intronless Transcripts	0.9999999999879	-1.21003780338754e-11	45	0	0	148	10287
R-HSA-6811438	Intra-Golgi traffic	0.9999999999879	-1.21003780338754e-11	45	0	0	148	10287
R-HSA-380108	Chemokine receptors bind chemokines	0.999999999988099	-1.19006178420092e-11	48	0	0	148	10287
R-HSA-392451	G beta:gamma signalling through PI3Kgamma	0.999999999988099	-1.19006178420092e-11	48	0	0	148	10287
R-HSA-73762	RNA Polymerase I Transcription Initiation	0.999999999988099	-1.19006178420092e-11	48	0	0	148	10287
R-HSA-69017	CDK-mediated phosphorylation and removal of Cdc6	0.999999999988167	-1.18326796139636e-11	52	0	0	148	10287
R-HSA-69229	Ubiquitin-dependent degradation of Cyclin D1	0.999999999988167	-1.18326796139636e-11	52	0	0	148	10287
R-HSA-75815	Ubiquitin-dependent degradation of Cyclin D	0.999999999988167	-1.18326796139636e-11	52	0	0	148	10287
R-HSA-350562	Regulation of ornithine decarboxylase (ODC)	0.999999999988167	-1.18326796139636e-11	52	0	0	148	10287
R-HSA-72662	Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S	0.999999999988275	-1.17245321690775e-11	63	0	0	148	10287
R-HSA-446219	Synthesis of substrates in N-glycan biosythesis	0.999999999988275	-1.17245321690775e-11	63	0	0	148	10287
R-HSA-73728	RNA Polymerase I Promoter Opening	0.999999999988275	-1.17245321690775e-11	63	0	0	148	10287
R-HSA-73933	Resolution of Abasic Sites (AP sites)	0.999999999988314	-1.16863449711136e-11	37	0	0	148	10287
R-HSA-73884	Base Excision Repair	0.999999999988314	-1.16863449711136e-11	37	0	0	148	10287
R-HSA-5689896	Ovarian tumor domain proteases	0.999999999988314	-1.16863449711136e-11	37	0	0	148	10287
R-HSA-176187	Activation of ATR in response to replication stress	0.999999999988314	-1.16863449711136e-11	37	0	0	148	10287
R-HSA-70895	Branched-chain amino acid catabolism	0.999999999988464	-1.1535873666148e-11	24	0	0	148	10287
R-HSA-937041	IKK complex recruitment mediated by RIP1	0.999999999988464	-1.1535873666148e-11	24	0	0	148	10287
R-HSA-110373	Resolution of AP sites via the multiple-nucleotide patch replacement pathway	0.999999999988464	-1.1535873666148e-11	24	0	0	148	10287
R-HSA-191273	Cholesterol biosynthesis	0.999999999988464	-1.1535873666148e-11	24	0	0	148	10287
R-HSA-193368	Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol	0.999999999988464	-1.1535873666148e-11	24	0	0	148	10287
R-HSA-156588	Glucuronidation	0.999999999988464	-1.1535873666148e-11	24	0	0	148	10287
R-HSA-174417	Telomere C-strand (Lagging Strand) Synthesis	0.999999999988464	-1.1535873666148e-11	24	0	0	148	10287
R-HSA-392154	Nitric oxide stimulates guanylate cyclase	0.999999999988464	-1.1535873666148e-11	24	0	0	148	10287
R-HSA-8868773	rRNA processing in the nucleus and cytosol	0.999999999988986	-1.10139668783666e-11	191	0	0	148	10287
R-HSA-8948216	Collagen chain trimerization	0.999999999989518	-1.04823411877263e-11	47	0	0	148	10287
R-HSA-1912422	Pre-NOTCH Expression and Processing	0.999999999989518	-1.04823411877263e-11	47	0	0	148	10287
R-HSA-1483249	Inositol phosphate metabolism	0.999999999989518	-1.04823411877263e-11	47	0	0	148	10287
R-HSA-421270	Cell-cell junction organization	0.999999999989781	-1.02187178912361e-11	61	0	0	148	10287
R-HSA-72702	Ribosomal scanning and start codon recognition	0.999999999989781	-1.02187178912361e-11	61	0	0	148	10287
R-HSA-5610785	GLI3 is processed to GLI3R by the proteasome	0.999999999989781	-1.02187178912361e-11	61	0	0	148	10287
R-HSA-187577	SCF(Skp2)-mediated degradation of p27/p21	0.999999999989781	-1.02187178912361e-11	61	0	0	148	10287
R-HSA-5610780	Degradation of GLI1 by the proteasome	0.999999999989781	-1.02187178912361e-11	61	0	0	148	10287
R-HSA-5610783	Degradation of GLI2 by the proteasome	0.999999999989781	-1.02187178912361e-11	61	0	0	148	10287
R-HSA-8852276	The role of GTSE1 in G2/M progression after G2 checkpoint	0.999999999989781	-1.02187178912361e-11	61	0	0	148	10287
R-HSA-5607761	Dectin-1 mediated noncanonical NF-kB signaling	0.999999999989781	-1.02187178912361e-11	61	0	0	148	10287
R-HSA-3301854	Nuclear Pore Complex (NPC) Disassembly	0.999999999989997	-1.00029584172353e-11	35	0	0	148	10287
R-HSA-6802948	Signaling by high-kinase activity BRAF mutants	0.999999999989997	-1.00029584172353e-11	35	0	0	148	10287
R-HSA-933541	TRAF6 mediated IRF7 activation	0.999999999989997	-1.00029584172353e-11	35	0	0	148	10287
R-HSA-4791275	Signaling by WNT in cancer	0.999999999989997	-1.00029584172353e-11	35	0	0	148	10287
R-HSA-159230	Transport of the SLBP Dependant Mature mRNA	0.999999999989997	-1.00029584172353e-11	35	0	0	148	10287
R-HSA-73980	RNA Polymerase III Transcription Termination	0.999999999990126	-9.87406892425695e-12	23	0	0	148	10287
R-HSA-5205685	Pink/Parkin Mediated Mitophagy	0.999999999990126	-9.87406892425695e-12	23	0	0	148	10287
R-HSA-400508	Incretin synthesis, secretion, and inactivation	0.999999999990126	-9.87406892425695e-12	23	0	0	148	10287
R-HSA-5627123	RHO GTPases activate PAKs	0.999999999990126	-9.87406892425695e-12	23	0	0	148	10287
R-HSA-2173795	Downregulation of SMAD2/3:SMAD4 transcriptional activity	0.999999999990126	-9.87406892425695e-12	23	0	0	148	10287
R-HSA-392170	ADP signalling through P2Y purinoceptor 12	0.999999999990126	-9.87406892425695e-12	23	0	0	148	10287
R-HSA-8863678	Neurodegenerative Diseases	0.999999999990126	-9.87406892425695e-12	23	0	0	148	10287
R-HSA-428930	Thromboxane signalling through TP receptor	0.999999999990126	-9.87406892425695e-12	23	0	0	148	10287
R-HSA-5654693	FRS-mediated FGFR1 signaling	0.999999999990126	-9.87406892425695e-12	23	0	0	148	10287
R-HSA-379726	Mitochondrial tRNA aminoacylation	0.999999999990126	-9.87406892425695e-12	23	0	0	148	10287
R-HSA-5205647	Mitophagy	0.999999999990126	-9.87406892425695e-12	23	0	0	148	10287
R-HSA-8855121	VLDL interactions	0.999999999990126	-9.87406892425695e-12	23	0	0	148	10287
R-HSA-5654695	PI-3K cascade:FGFR2	0.999999999990126	-9.87406892425695e-12	23	0	0	148	10287
R-HSA-5654699	SHC-mediated cascade:FGFR2	0.999999999990126	-9.87406892425695e-12	23	0	0	148	10287
R-HSA-8862803	Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models	0.999999999990126	-9.87406892425695e-12	23	0	0	148	10287
R-HSA-5365859	RA biosynthesis pathway	0.999999999990126	-9.87406892425695e-12	23	0	0	148	10287
R-HSA-174048	APC/C:Cdc20 mediated degradation of Cyclin B	0.999999999990126	-9.87406892425695e-12	23	0	0	148	10287
R-HSA-5620922	BBSome-mediated cargo-targeting to cilium	0.999999999990126	-9.87406892425695e-12	23	0	0	148	10287
R-HSA-211000	Gene Silencing by RNA	0.999999999990593	-9.40684087760734e-12	137	0	0	148	10287
R-HSA-5336415	Uptake and function of diphtheria toxin	0.999999999990648	-9.35213556567091e-12	6	0	0	148	10287
R-HSA-193670	p75NTR negatively regulates cell cycle via SC1	0.999999999990648	-9.35213556567091e-12	6	0	0	148	10287
R-HSA-3134973	LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production	0.999999999990648	-9.35213556567091e-12	6	0	0	148	10287
R-HSA-388479	Vasopressin-like receptors	0.999999999990648	-9.35213556567091e-12	6	0	0	148	10287
R-HSA-6782861	Synthesis of wybutosine at G37 of tRNA(Phe)	0.999999999990648	-9.35213556567091e-12	6	0	0	148	10287
R-HSA-500753	Pyrimidine biosynthesis	0.999999999990648	-9.35213556567091e-12	6	0	0	148	10287
R-HSA-6787639	GDP-fucose biosynthesis	0.999999999990648	-9.35213556567091e-12	6	0	0	148	10287
R-HSA-6793080	rRNA modification in the mitochondrion	0.999999999990648	-9.35213556567091e-12	6	0	0	148	10287
R-HSA-190370	FGFR1b ligand binding and activation	0.999999999990648	-9.35213556567091e-12	6	0	0	148	10287
R-HSA-193144	Estrogen biosynthesis	0.999999999990648	-9.35213556567091e-12	6	0	0	148	10287
R-HSA-3323169	Defects in biotin (Btn) metabolism	0.999999999990648	-9.35213556567091e-12	6	0	0	148	10287
R-HSA-8851907	MET activates PI3K/AKT signaling	0.999999999990648	-9.35213556567091e-12	6	0	0	148	10287
R-HSA-5660668	CLEC7A/inflammasome pathway	0.999999999990648	-9.35213556567091e-12	6	0	0	148	10287
R-HSA-390247	Beta-oxidation of very long chain fatty acids	0.999999999990648	-9.35213556567091e-12	6	0	0	148	10287
R-HSA-176417	Phosphorylation of Emi1	0.999999999990648	-9.35213556567091e-12	6	0	0	148	10287
R-HSA-1482798	Acyl chain remodeling of CL	0.999999999990648	-9.35213556567091e-12	6	0	0	148	10287
R-HSA-1237112	Methionine salvage pathway	0.999999999990648	-9.35213556567091e-12	6	0	0	148	10287
R-HSA-5676934	Protein repair	0.999999999990648	-9.35213556567091e-12	6	0	0	148	10287
R-HSA-1566977	Fibronectin matrix formation	0.999999999990648	-9.35213556567091e-12	6	0	0	148	10287
R-HSA-2142700	Synthesis of Lipoxins (LX)	0.999999999990648	-9.35213556567091e-12	6	0	0	148	10287
R-HSA-193993	Mineralocorticoid biosynthesis	0.999999999990648	-9.35213556567091e-12	6	0	0	148	10287
R-HSA-5693548	Sensing of DNA Double Strand Breaks	0.999999999990648	-9.35213556567091e-12	6	0	0	148	10287
R-HSA-947581	Molybdenum cofactor biosynthesis	0.999999999990648	-9.35213556567091e-12	6	0	0	148	10287
R-HSA-5626978	TNFR1-mediated ceramide production	0.999999999990648	-9.35213556567091e-12	6	0	0	148	10287
R-HSA-2142712	Synthesis of 12-eicosatetraenoic acid derivatives	0.999999999990648	-9.35213556567091e-12	6	0	0	148	10287
R-HSA-173623	Classical antibody-mediated complement activation	0.999999999990648	-9.35213556567091e-12	6	0	0	148	10287
R-HSA-5579029	Metabolic disorders of biological oxidation enzymes	0.999999999990648	-9.35213556567091e-12	6	0	0	148	10287
R-HSA-68616	Assembly of the ORC complex at the origin of replication	0.999999999990648	-9.35213556567091e-12	6	0	0	148	10287
R-HSA-205025	NADE modulates death signalling	0.999999999990648	-9.35213556567091e-12	6	0	0	148	10287
R-HSA-8849470	PTK6 Regulates Cell Cycle	0.999999999990648	-9.35213556567091e-12	6	0	0	148	10287
R-HSA-3371599	Defective HLCS causes multiple carboxylase deficiency	0.999999999990648	-9.35213556567091e-12	6	0	0	148	10287
R-HSA-111957	Cam-PDE 1 activation	0.999999999990648	-9.35213556567091e-12	6	0	0	148	10287
R-HSA-8857538	PTK6 promotes HIF1A stabilization	0.999999999990648	-9.35213556567091e-12	6	0	0	148	10287
R-HSA-187015	Activation of TRKA receptors	0.999999999990648	-9.35213556567091e-12	6	0	0	148	10287
R-HSA-3065679	SUMO is proteolytically processed	0.999999999990648	-9.35213556567091e-12	6	0	0	148	10287
R-HSA-77288	mitochondrial fatty acid beta-oxidation of unsaturated fatty acids	0.999999999990648	-9.35213556567091e-12	6	0	0	148	10287
R-HSA-2187335	The retinoid cycle in cones (daylight vision)	0.999999999990648	-9.35213556567091e-12	6	0	0	148	10287
R-HSA-211916	Vitamins	0.999999999990648	-9.35213556567091e-12	6	0	0	148	10287
R-HSA-2142770	Synthesis of 15-eicosatetraenoic acid derivatives	0.999999999990648	-9.35213556567091e-12	6	0	0	148	10287
R-HSA-442717	CREB phosphorylation through the activation of CaMKK	0.999999999990648	-9.35213556567091e-12	6	0	0	148	10287
R-HSA-177135	Conjugation of benzoate with glycine	0.999999999990648	-9.35213556567091e-12	6	0	0	148	10287
R-HSA-428808	Na+-dependent glucose transporters	0.999999999990648	-9.35213556567091e-12	6	0	0	148	10287
R-HSA-444257	RSK activation	0.999999999990648	-9.35213556567091e-12	6	0	0	148	10287
R-HSA-3304356	SMAD2/3 Phosphorylation Motif Mutants in Cancer	0.999999999990648	-9.35213556567091e-12	6	0	0	148	10287
R-HSA-6806942	MET Receptor Activation	0.999999999990648	-9.35213556567091e-12	6	0	0	148	10287
R-HSA-166662	Lectin pathway of complement activation	0.999999999990648	-9.35213556567091e-12	6	0	0	148	10287
R-HSA-5624138	Trafficking of myristoylated proteins to the cilium	0.999999999990648	-9.35213556567091e-12	6	0	0	148	10287
R-HSA-6798163	Choline catabolism	0.999999999990648	-9.35213556567091e-12	6	0	0	148	10287
R-HSA-5368598	Negative regulation of TCF-dependent signaling by DVL-interacting proteins	0.999999999990648	-9.35213556567091e-12	6	0	0	148	10287
R-HSA-5674499	Negative feedback regulation of MAPK pathway	0.999999999990648	-9.35213556567091e-12	6	0	0	148	10287
R-HSA-446199	Synthesis of Dolichyl-phosphate	0.999999999990648	-9.35213556567091e-12	6	0	0	148	10287
R-HSA-5339717	Misspliced LRP5 mutants have enhanced beta-catenin-dependent signaling	0.999999999990648	-9.35213556567091e-12	6	0	0	148	10287
R-HSA-6799990	Metal sequestration by antimicrobial proteins	0.999999999990648	-9.35213556567091e-12	6	0	0	148	10287
R-HSA-3000484	Scavenging by Class F Receptors	0.999999999990648	-9.35213556567091e-12	6	0	0	148	10287
R-HSA-69615	G1/S DNA Damage Checkpoints	0.999999999990776	-9.22380224530453e-12	67	0	0	148	10287
R-HSA-5358346	Hedgehog ligand biogenesis	0.999999999990776	-9.22380224530453e-12	67	0	0	148	10287
R-HSA-5625886	Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3	0.999999999990776	-9.22380224530453e-12	67	0	0	148	10287
R-HSA-4608870	Asymmetric localization of PCP proteins	0.999999999990776	-9.22380224530453e-12	67	0	0	148	10287
R-HSA-1234176	Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha	0.999999999990776	-9.22380224530453e-12	67	0	0	148	10287
R-HSA-1632852	Macroautophagy	0.999999999990776	-9.22380224530453e-12	67	0	0	148	10287
R-HSA-912446	Meiotic recombination	0.999999999990812	-9.18837013015418e-12	88	0	0	148	10287
R-HSA-5389840	Mitochondrial translation elongation	0.999999999990812	-9.18837013015418e-12	88	0	0	148	10287
R-HSA-174084	Autodegradation of Cdh1 by Cdh1:APC/C	0.999999999990922	-9.07809796163139e-12	64	0	0	148	10287
R-HSA-1296071	Potassium Channels	0.999999999991062	-8.93829999670208e-12	100	0	0	148	10287
R-HSA-5663084	Diseases of carbohydrate metabolism	0.99999999999124	-8.76016246204904e-12	10	0	0	148	10287
R-HSA-74259	Purine catabolism	0.99999999999124	-8.76016246204904e-12	10	0	0	148	10287
R-HSA-428643	Organic anion transporters	0.99999999999124	-8.76016246204904e-12	10	0	0	148	10287
R-HSA-8875656	MET receptor recycling	0.99999999999124	-8.76016246204904e-12	10	0	0	148	10287
R-HSA-2151209	Activation of PPARGC1A (PGC-1alpha) by phosphorylation	0.99999999999124	-8.76016246204904e-12	10	0	0	148	10287
R-HSA-8868766	rRNA processing in the mitochondrion	0.99999999999124	-8.76016246204904e-12	10	0	0	148	10287
R-HSA-168799	Neurotoxicity of clostridium toxins	0.99999999999124	-8.76016246204904e-12	10	0	0	148	10287
R-HSA-1250342	PI3K events in ERBB4 signaling	0.99999999999124	-8.76016246204904e-12	10	0	0	148	10287
R-HSA-196108	Pregnenolone biosynthesis	0.99999999999124	-8.76016246204904e-12	10	0	0	148	10287
R-HSA-209968	Thyroxine biosynthesis	0.99999999999124	-8.76016246204904e-12	10	0	0	148	10287
R-HSA-1660517	Synthesis of PIPs at the late endosome membrane	0.99999999999124	-8.76016246204904e-12	10	0	0	148	10287
R-HSA-73929	Base-Excision Repair, AP Site Formation	0.99999999999124	-8.76016246204904e-12	10	0	0	148	10287
R-HSA-193692	Regulated proteolysis of p75NTR	0.99999999999124	-8.76016246204904e-12	10	0	0	148	10287
R-HSA-975578	Reactions specific to the complex N-glycan synthesis pathway	0.99999999999124	-8.76016246204904e-12	10	0	0	148	10287
R-HSA-167590	Nef Mediated CD4 Down-regulation	0.99999999999124	-8.76016246204904e-12	10	0	0	148	10287
R-HSA-3229121	Glycogen storage diseases	0.99999999999124	-8.76016246204904e-12	10	0	0	148	10287
R-HSA-113507	E2F-enabled inhibition of pre-replication complex formation	0.99999999999124	-8.76016246204904e-12	10	0	0	148	10287
R-HSA-425381	Bicarbonate transporters	0.99999999999124	-8.76016246204904e-12	10	0	0	148	10287
R-HSA-389887	Beta-oxidation of pristanoyl-CoA	0.99999999999124	-8.76016246204904e-12	10	0	0	148	10287
R-HSA-74749	Signal attenuation	0.99999999999124	-8.76016246204904e-12	10	0	0	148	10287
R-HSA-418886	Netrin mediated repulsion signals	0.99999999999124	-8.76016246204904e-12	10	0	0	148	10287
R-HSA-112311	Neurotransmitter Clearance In The Synaptic Cleft	0.99999999999124	-8.76016246204904e-12	10	0	0	148	10287
R-HSA-70635	Urea cycle	0.99999999999124	-8.76016246204904e-12	10	0	0	148	10287
R-HSA-430116	GP1b-IX-V activation signalling	0.99999999999124	-8.76016246204904e-12	10	0	0	148	10287
R-HSA-110056	MAPK3 (ERK1) activation	0.99999999999124	-8.76016246204904e-12	10	0	0	148	10287
R-HSA-3785653	Myoclonic epilepsy of Lafora	0.99999999999124	-8.76016246204904e-12	10	0	0	148	10287
R-HSA-419812	Calcitonin-like ligand receptors	0.99999999999124	-8.76016246204904e-12	10	0	0	148	10287
R-HSA-2562578	TRIF-mediated programmed cell death	0.99999999999124	-8.76016246204904e-12	10	0	0	148	10287
R-HSA-1300644	Interaction With The Zona Pellucida	0.99999999999124	-8.76016246204904e-12	10	0	0	148	10287
R-HSA-450341	Activation of the AP-1 family of transcription factors	0.99999999999124	-8.76016246204904e-12	10	0	0	148	10287
R-HSA-427601	Multifunctional anion exchangers	0.99999999999124	-8.76016246204904e-12	10	0	0	148	10287
R-HSA-727802	Transport of nucleotide sugars	0.99999999999124	-8.76016246204904e-12	10	0	0	148	10287
R-HSA-77286	mitochondrial fatty acid beta-oxidation of saturated fatty acids	0.99999999999124	-8.76016246204904e-12	10	0	0	148	10287
R-HSA-190377	FGFR2b ligand binding and activation	0.99999999999124	-8.76016246204904e-12	10	0	0	148	10287
R-HSA-937042	IRAK2 mediated activation of TAK1 complex	0.99999999999124	-8.76016246204904e-12	10	0	0	148	10287
R-HSA-139915	Activation of PUMA and translocation to mitochondria	0.99999999999124	-8.76016246204904e-12	10	0	0	148	10287
R-HSA-174437	Removal of the Flap Intermediate from the C-strand	0.99999999999124	-8.76016246204904e-12	10	0	0	148	10287
R-HSA-2465910	MASTL Facilitates Mitotic Progression	0.99999999999124	-8.76016246204904e-12	10	0	0	148	10287
R-HSA-190873	Gap junction degradation	0.99999999999124	-8.76016246204904e-12	10	0	0	148	10287
R-HSA-2161522	Abacavir transport and metabolism	0.99999999999124	-8.76016246204904e-12	10	0	0	148	10287
R-HSA-164940	Nef mediated downregulation of MHC class I complex cell surface expression	0.99999999999124	-8.76016246204904e-12	10	0	0	148	10287
R-HSA-418890	Role of second messengers in netrin-1 signaling	0.99999999999124	-8.76016246204904e-12	10	0	0	148	10287
R-HSA-1855167	Synthesis of pyrophosphates in the cytosol	0.99999999999124	-8.76016246204904e-12	10	0	0	148	10287
R-HSA-201688	WNT mediated activation of DVL	0.99999999999124	-8.76016246204904e-12	10	0	0	148	10287
R-HSA-8853334	Signaling by FGFR3 fusions in cancer	0.99999999999124	-8.76016246204904e-12	10	0	0	148	10287
R-HSA-3215018	Processing and activation of SUMO	0.99999999999124	-8.76016246204904e-12	10	0	0	148	10287
R-HSA-390450	Folding of actin by CCT/TriC	0.99999999999124	-8.76016246204904e-12	10	0	0	148	10287
R-HSA-5687613	Diseases associated with surfactant metabolism	0.99999999999124	-8.76016246204904e-12	10	0	0	148	10287
R-HSA-2408522	Selenoamino acid metabolism	0.999999999991286	-8.71450678399824e-12	121	0	0	148	10287
R-HSA-2022854	Keratan sulfate biosynthesis	0.999999999991561	-8.4389557425232e-12	28	0	0	148	10287
R-HSA-354192	Integrin alphaIIb beta3 signaling	0.999999999991561	-8.4389557425232e-12	28	0	0	148	10287
R-HSA-76061	RNA Polymerase III Transcription Initiation From Type 1 Promoter	0.999999999991561	-8.4389557425232e-12	28	0	0	148	10287
R-HSA-1483191	Synthesis of PC	0.999999999991561	-8.4389557425232e-12	28	0	0	148	10287
R-HSA-76071	RNA Polymerase III Transcription Initiation From Type 3 Promoter	0.999999999991561	-8.4389557425232e-12	28	0	0	148	10287
R-HSA-5357769	Caspase activation via extrinsic apoptotic signalling pathway	0.999999999991561	-8.4389557425232e-12	28	0	0	148	10287
R-HSA-400042	Adrenaline,noradrenaline inhibits insulin secretion	0.999999999991561	-8.4389557425232e-12	28	0	0	148	10287
R-HSA-917729	Endosomal Sorting Complex Required For Transport (ESCRT)	0.999999999991561	-8.4389557425232e-12	28	0	0	148	10287
R-HSA-190828	Gap junction trafficking	0.999999999991561	-8.4389557425232e-12	28	0	0	148	10287
R-HSA-437239	Recycling pathway of L1	0.999999999991561	-8.4389557425232e-12	28	0	0	148	10287
R-HSA-1266695	Interleukin-7 signaling	0.999999999991561	-8.4389557425232e-12	28	0	0	148	10287
R-HSA-5621480	Dectin-2 family	0.999999999991561	-8.4389557425232e-12	28	0	0	148	10287
R-HSA-174800	Chylomicron-mediated lipid transport	0.999999999991561	-8.4389557425232e-12	28	0	0	148	10287
R-HSA-1855204	Synthesis of IP3 and IP4 in the cytosol	0.999999999991561	-8.4389557425232e-12	28	0	0	148	10287
R-HSA-1368082	RORA activates gene expression	0.999999999991561	-8.4389557425232e-12	28	0	0	148	10287
R-HSA-194002	Glucocorticoid biosynthesis	0.99999999999157	-8.42995274838699e-12	9	0	0	148	10287
R-HSA-5340588	RNF mutants show enhanced WNT signaling and proliferation	0.99999999999157	-8.42995274838699e-12	9	0	0	148	10287
R-HSA-2142816	Synthesis of (16-20)-hydroxyeicosatetraenoic acids (HETE)	0.99999999999157	-8.42995274838699e-12	9	0	0	148	10287
R-HSA-156587	Amino Acid conjugation	0.99999999999157	-8.42995274838699e-12	9	0	0	148	10287
R-HSA-391908	Prostanoid ligand receptors	0.99999999999157	-8.42995274838699e-12	9	0	0	148	10287
R-HSA-110357	Displacement of DNA glycosylase by APEX1	0.99999999999157	-8.42995274838699e-12	9	0	0	148	10287
R-HSA-162592	Integration of provirus	0.99999999999157	-8.42995274838699e-12	9	0	0	148	10287
R-HSA-2243919	Crosslinking of collagen fibrils	0.99999999999157	-8.42995274838699e-12	9	0	0	148	10287
R-HSA-419771	Opsins	0.99999999999157	-8.42995274838699e-12	9	0	0	148	10287
R-HSA-8854691	Interleukin-19, 20, 22, 24	0.99999999999157	-8.42995274838699e-12	9	0	0	148	10287
R-HSA-1300642	Sperm Motility And Taxes	0.99999999999157	-8.42995274838699e-12	9	0	0	148	10287
R-HSA-1247673	Erythrocytes take up oxygen and release carbon dioxide	0.99999999999157	-8.42995274838699e-12	9	0	0	148	10287
R-HSA-425986	Sodium/Proton exchangers	0.99999999999157	-8.42995274838699e-12	9	0	0	148	10287
R-HSA-166665	Terminal pathway of complement	0.99999999999157	-8.42995274838699e-12	9	0	0	148	10287
R-HSA-428890	Role of Abl in Robo-Slit signaling	0.99999999999157	-8.42995274838699e-12	9	0	0	148	10287
R-HSA-2474795	Diseases associated with visual transduction	0.99999999999157	-8.42995274838699e-12	9	0	0	148	10287
R-HSA-426486	Small interfering RNA (siRNA) biogenesis	0.99999999999157	-8.42995274838699e-12	9	0	0	148	10287
R-HSA-2142688	Synthesis of 5-eicosatetraenoic acids	0.99999999999157	-8.42995274838699e-12	9	0	0	148	10287
R-HSA-74182	Ketone body metabolism	0.99999999999157	-8.42995274838699e-12	9	0	0	148	10287
R-HSA-3304351	Signaling by TGF-beta Receptor Complex in Cancer	0.99999999999157	-8.42995274838699e-12	9	0	0	148	10287
R-HSA-112411	MAPK1 (ERK2) activation	0.99999999999157	-8.42995274838699e-12	9	0	0	148	10287
R-HSA-189085	Digestion of dietary carbohydrate	0.99999999999157	-8.42995274838699e-12	9	0	0	148	10287
R-HSA-2453864	Retinoid cycle disease events	0.99999999999157	-8.42995274838699e-12	9	0	0	148	10287
R-HSA-8849469	PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1	0.99999999999157	-8.42995274838699e-12	9	0	0	148	10287
R-HSA-390696	Adrenoceptors	0.99999999999157	-8.42995274838699e-12	9	0	0	148	10287
R-HSA-8876493	InlA-mediated entry of Listeria monocytogenes into host cells	0.99999999999157	-8.42995274838699e-12	9	0	0	148	10287
R-HSA-1614558	Degradation of cysteine and homocysteine	0.99999999999157	-8.42995274838699e-12	9	0	0	148	10287
R-HSA-75094	Formation of the Editosome	0.99999999999157	-8.42995274838699e-12	9	0	0	148	10287
R-HSA-629597	Highly calcium permeable nicotinic acetylcholine receptors	0.99999999999157	-8.42995274838699e-12	9	0	0	148	10287
R-HSA-193697	p75NTR regulates axonogenesis	0.99999999999157	-8.42995274838699e-12	9	0	0	148	10287
R-HSA-159424	Conjugation of carboxylic acids	0.99999999999157	-8.42995274838699e-12	9	0	0	148	10287
R-HSA-196025	Formation of annular gap junctions	0.99999999999157	-8.42995274838699e-12	9	0	0	148	10287
R-HSA-71336	Pentose phosphate pathway (hexose monophosphate shunt)	0.99999999999157	-8.42995274838699e-12	9	0	0	148	10287
R-HSA-2214320	Anchoring fibril formation	0.99999999999157	-8.42995274838699e-12	9	0	0	148	10287
R-HSA-447041	CHL1 interactions	0.99999999999157	-8.42995274838699e-12	9	0	0	148	10287
R-HSA-2428933	SHC-related events triggered by IGF1R	0.99999999999157	-8.42995274838699e-12	9	0	0	148	10287
R-HSA-198693	AKT phosphorylates targets in the nucleus	0.99999999999157	-8.42995274838699e-12	9	0	0	148	10287
R-HSA-1296052	Ca2+ activated K+ channels	0.99999999999157	-8.42995274838699e-12	9	0	0	148	10287
R-HSA-163765	ChREBP activates metabolic gene expression	0.99999999999157	-8.42995274838699e-12	9	0	0	148	10287
R-HSA-72200	mRNA Editing: C to U Conversion	0.99999999999157	-8.42995274838699e-12	9	0	0	148	10287
R-HSA-1462054	Alpha-defensins	0.99999999999157	-8.42995274838699e-12	9	0	0	148	10287
R-HSA-6806834	Signaling by MET	0.999999999991626	-8.37439099067136e-12	69	0	0	148	10287
R-HSA-5693571	Nonhomologous End-Joining (NHEJ)	0.999999999991626	-8.37439099067136e-12	69	0	0	148	10287
R-HSA-204005	COPII (Coat Protein 2) Mediated Vesicle Transport	0.999999999991626	-8.37439099067136e-12	69	0	0	148	10287
R-HSA-427359	SIRT1 negatively regulates rRNA Expression	0.999999999991626	-8.37439099067136e-12	69	0	0	148	10287
R-HSA-68867	Assembly of the pre-replicative complex	0.999999999991626	-8.37439099067136e-12	69	0	0	148	10287
R-HSA-5619084	ABC transporter disorders	0.999999999991626	-8.37439099067136e-12	69	0	0	148	10287
R-HSA-2559582	Senescence-Associated Secretory Phenotype (SASP)	0.999999999991953	-8.04680394482972e-12	110	0	0	148	10287
R-HSA-5250941	Negative epigenetic regulation of rRNA expression	0.999999999991953	-8.04680394482972e-12	110	0	0	148	10287
R-HSA-73854	RNA Polymerase I Promoter Clearance	0.999999999991953	-8.04680394482972e-12	110	0	0	148	10287
R-HSA-2426168	Activation of gene expression by SREBF (SREBP)	0.999999999992179	-7.82081415283333e-12	42	0	0	148	10287
R-HSA-8866654	E3 ubiquitin ligases ubiquitinate target proteins	0.999999999992179	-7.82081415283333e-12	42	0	0	148	10287
R-HSA-168253	Host Interactions with Influenza Factors	0.999999999992179	-7.82081415283333e-12	42	0	0	148	10287
R-HSA-6782315	tRNA modification in the nucleus and cytosol	0.999999999992179	-7.82081415283333e-12	42	0	0	148	10287
R-HSA-1566948	Elastic fibre formation	0.999999999992179	-7.82081415283333e-12	42	0	0	148	10287
R-HSA-1461957	Beta defensins	0.999999999992179	-7.82081415283333e-12	42	0	0	148	10287
R-HSA-5368287	Mitochondrial translation	0.999999999992416	-7.58450673361751e-12	94	0	0	148	10287
R-HSA-3214815	HDACs deacetylate histones	0.999999999992416	-7.58450673361751e-12	94	0	0	148	10287
R-HSA-5419276	Mitochondrial translation termination	0.999999999992843	-7.15746208208609e-12	87	0	0	148	10287
R-HSA-453276	Regulation of mitotic cell cycle	0.999999999992843	-7.15746208208609e-12	87	0	0	148	10287
R-HSA-6811558	PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling	0.999999999992843	-7.15746208208609e-12	87	0	0	148	10287
R-HSA-351202	Metabolism of polyamines	0.999999999992843	-7.15746208208609e-12	87	0	0	148	10287
R-HSA-72202	Transport of Mature Transcript to Cytoplasm	0.999999999992843	-7.15746208208609e-12	87	0	0	148	10287
R-HSA-174143	APC/C-mediated degradation of cell cycle proteins	0.999999999992843	-7.15746208208609e-12	87	0	0	148	10287
R-HSA-5368286	Mitochondrial translation initiation	0.999999999992843	-7.15746208208609e-12	87	0	0	148	10287
R-HSA-182218	Nef Mediated CD8 Down-regulation	0.999999999992936	-7.06363609085345e-12	7	0	0	148	10287
R-HSA-3304349	Loss of Function of SMAD2/3 in Cancer	0.999999999992936	-7.06363609085345e-12	7	0	0	148	10287
R-HSA-447043	Neurofascin interactions	0.999999999992936	-7.06363609085345e-12	7	0	0	148	10287
R-HSA-73943	Reversal of alkylation damage by DNA dioxygenases	0.999999999992936	-7.06363609085345e-12	7	0	0	148	10287
R-HSA-2993913	Clearance of Nuclear Envelope Membranes from Chromatin	0.999999999992936	-7.06363609085345e-12	7	0	0	148	10287
R-HSA-3656225	Defective CHST6 causes MCDC1	0.999999999992936	-7.06363609085345e-12	7	0	0	148	10287
R-HSA-199920	CREB phosphorylation	0.999999999992936	-7.06363609085345e-12	7	0	0	148	10287
R-HSA-435368	Zinc efflux and compartmentalization by the SLC30 family	0.999999999992936	-7.06363609085345e-12	7	0	0	148	10287
R-HSA-5652084	Fructose metabolism	0.999999999992936	-7.06363609085345e-12	7	0	0	148	10287
R-HSA-447038	NrCAM interactions	0.999999999992936	-7.06363609085345e-12	7	0	0	148	10287
R-HSA-83936	Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane	0.999999999992936	-7.06363609085345e-12	7	0	0	148	10287
R-HSA-111471	Apoptotic factor-mediated response	0.999999999992936	-7.06363609085345e-12	7	0	0	148	10287
R-HSA-75158	TRAIL  signaling	0.999999999992936	-7.06363609085345e-12	7	0	0	148	10287
R-HSA-196791	Vitamin D (calciferol) metabolism	0.999999999992936	-7.06363609085345e-12	7	0	0	148	10287
R-HSA-629587	Highly sodium permeable acetylcholine nicotinic receptors	0.999999999992936	-7.06363609085345e-12	7	0	0	148	10287
R-HSA-3595177	Defective CHSY1 causes TPBS	0.999999999992936	-7.06363609085345e-12	7	0	0	148	10287
R-HSA-171319	Telomere Extension By Telomerase	0.999999999992936	-7.06363609085345e-12	7	0	0	148	10287
R-HSA-110362	POLB-Dependent Long Patch Base Excision Repair	0.999999999992936	-7.06363609085345e-12	7	0	0	148	10287
R-HSA-174362	Transport and synthesis of PAPS	0.999999999992936	-7.06363609085345e-12	7	0	0	148	10287
R-HSA-3315487	SMAD2/3 MH2 Domain Mutants in Cancer	0.999999999992936	-7.06363609085345e-12	7	0	0	148	10287
R-HSA-162791	Attachment of GPI anchor to uPAR	0.999999999992936	-7.06363609085345e-12	7	0	0	148	10287
R-HSA-426117	Cation-coupled Chloride cotransporters	0.999999999992936	-7.06363609085345e-12	7	0	0	148	10287
R-HSA-190371	FGFR3b ligand binding and activation	0.999999999992936	-7.06363609085345e-12	7	0	0	148	10287
R-HSA-210744	Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells	0.999999999992936	-7.06363609085345e-12	7	0	0	148	10287
R-HSA-2660826	Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant	0.999999999992936	-7.06363609085345e-12	7	0	0	148	10287
R-HSA-3065678	SUMO is transferred from E1 to E2 (UBE2I, UBC9)	0.999999999992936	-7.06363609085345e-12	7	0	0	148	10287
R-HSA-3656244	Defective B4GALT1 causes B4GALT1-CDG (CDG-2d)	0.999999999992936	-7.06363609085345e-12	7	0	0	148	10287
R-HSA-3595174	Defective CHST14 causes EDS, musculocontractural type	0.999999999992936	-7.06363609085345e-12	7	0	0	148	10287
R-HSA-163767	PP2A-mediated dephosphorylation of key metabolic factors	0.999999999992936	-7.06363609085345e-12	7	0	0	148	10287
R-HSA-6814848	Glycerophospholipid catabolism	0.999999999992936	-7.06363609085345e-12	7	0	0	148	10287
R-HSA-5619102	SLC transporter disorders	0.999999999992936	-7.06363609085345e-12	7	0	0	148	10287
R-HSA-5576894	Phase 1 - inactivation of fast Na+ channels	0.999999999992936	-7.06363609085345e-12	7	0	0	148	10287
R-HSA-196843	Vitamin B2 (riboflavin) metabolism	0.999999999992936	-7.06363609085345e-12	7	0	0	148	10287
R-HSA-420597	Nectin/Necl  trans heterodimerization	0.999999999992936	-7.06363609085345e-12	7	0	0	148	10287
R-HSA-5603029	IkBA variant leads to EDA-ID	0.999999999992936	-7.06363609085345e-12	7	0	0	148	10287
R-HSA-5649702	APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway	0.999999999992936	-7.06363609085345e-12	7	0	0	148	10287
R-HSA-3595172	Defective CHST3 causes SEDCJD	0.999999999992936	-7.06363609085345e-12	7	0	0	148	10287
R-HSA-2660825	Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant	0.999999999992936	-7.06363609085345e-12	7	0	0	148	10287
R-HSA-448706	Interleukin-1 processing	0.999999999992936	-7.06363609085345e-12	7	0	0	148	10287
R-HSA-433692	Proton-coupled monocarboxylate transport	0.999999999992936	-7.06363609085345e-12	7	0	0	148	10287
R-HSA-3656243	Defective ST3GAL3 causes MCT12 and EIEE15	0.999999999992936	-7.06363609085345e-12	7	0	0	148	10287
R-HSA-2980767	Activation of NIMA Kinases NEK9, NEK6, NEK7	0.999999999992936	-7.06363609085345e-12	7	0	0	148	10287
R-HSA-1912399	Pre-NOTCH Processing in the Endoplasmic Reticulum	0.999999999992936	-7.06363609085345e-12	7	0	0	148	10287
R-HSA-164843	2-LTR circle formation	0.999999999992936	-7.06363609085345e-12	7	0	0	148	10287
R-HSA-426496	Post-transcriptional silencing by small RNAs	0.999999999992936	-7.06363609085345e-12	7	0	0	148	10287
R-HSA-2393930	Phosphate bond hydrolysis by NUDT proteins	0.999999999992936	-7.06363609085345e-12	7	0	0	148	10287
R-HSA-975956	Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)	0.9999999999931	-6.89994680928511e-12	99	0	0	148	10287
R-HSA-176408	Regulation of APC/C activators between G1/S and early anaphase	0.999999999993274	-6.72643361767789e-12	81	0	0	148	10287
R-HSA-174184	Cdc20:Phospho-APC/C mediated degradation of Cyclin A	0.999999999993766	-6.23375991875551e-12	73	0	0	148	10287
R-HSA-174178	APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1	0.999999999993766	-6.23375991875551e-12	73	0	0	148	10287
R-HSA-421837	Clathrin derived vesicle budding	0.999999999993766	-6.23375991875551e-12	73	0	0	148	10287
R-HSA-199992	trans-Golgi Network Vesicle Budding	0.999999999993766	-6.23375991875551e-12	73	0	0	148	10287
R-HSA-879518	Transport of organic anions	0.999999999994353	-5.64698471550593e-12	12	0	0	148	10287
R-HSA-1475029	Reversible hydration of carbon dioxide	0.999999999994353	-5.64698471550593e-12	12	0	0	148	10287
R-HSA-2160916	Hyaluronan uptake and degradation	0.999999999994353	-5.64698471550593e-12	12	0	0	148	10287
R-HSA-203615	eNOS activation	0.999999999994353	-5.64698471550593e-12	12	0	0	148	10287
R-HSA-1839130	Signaling by activated point mutants of FGFR3	0.999999999994353	-5.64698471550593e-12	12	0	0	148	10287
R-HSA-75035	Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex	0.999999999994353	-5.64698471550593e-12	12	0	0	148	10287
R-HSA-3371511	HSF1 activation	0.999999999994353	-5.64698471550593e-12	12	0	0	148	10287
R-HSA-2022857	Keratan sulfate degradation	0.999999999994353	-5.64698471550593e-12	12	0	0	148	10287
R-HSA-190373	FGFR1c ligand binding and activation	0.999999999994353	-5.64698471550593e-12	12	0	0	148	10287
R-HSA-8851680	Butyrophilin (BTN) family interactions	0.999999999994353	-5.64698471550593e-12	12	0	0	148	10287
R-HSA-451308	Activation of Ca-permeable Kainate Receptor	0.999999999994353	-5.64698471550593e-12	12	0	0	148	10287
R-HSA-3656237	Defective EXT2 causes exostoses 2	0.999999999994353	-5.64698471550593e-12	12	0	0	148	10287
R-HSA-451306	Ionotropic activity of Kainate Receptors	0.999999999994353	-5.64698471550593e-12	12	0	0	148	10287
R-HSA-390666	Serotonin receptors	0.999999999994353	-5.64698471550593e-12	12	0	0	148	10287
R-HSA-73621	Pyrimidine catabolism	0.999999999994353	-5.64698471550593e-12	12	0	0	148	10287
R-HSA-71384	Ethanol oxidation	0.999999999994353	-5.64698471550593e-12	12	0	0	148	10287
R-HSA-2468052	Establishment of Sister Chromatid Cohesion	0.999999999994353	-5.64698471550593e-12	12	0	0	148	10287
R-HSA-211958	Miscellaneous substrates	0.999999999994353	-5.64698471550593e-12	12	0	0	148	10287
R-HSA-1296346	Tandem pore domain potassium channels	0.999999999994353	-5.64698471550593e-12	12	0	0	148	10287
R-HSA-176974	Unwinding of DNA	0.999999999994353	-5.64698471550593e-12	12	0	0	148	10287
R-HSA-71064	Lysine catabolism	0.999999999994353	-5.64698471550593e-12	12	0	0	148	10287
R-HSA-209822	Glycoprotein hormones	0.999999999994353	-5.64698471550593e-12	12	0	0	148	10287
R-HSA-975110	TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling	0.999999999994353	-5.64698471550593e-12	12	0	0	148	10287
R-HSA-3656253	Defective EXT1 causes exostoses 1, TRPS2 and CHDS	0.999999999994353	-5.64698471550593e-12	12	0	0	148	10287
R-HSA-8866427	VLDLR internalisation and degradation	0.999999999994353	-5.64698471550593e-12	12	0	0	148	10287
R-HSA-417957	P2Y receptors	0.999999999994353	-5.64698471550593e-12	12	0	0	148	10287
R-HSA-2033514	FGFR3 mutant receptor activation	0.999999999994353	-5.64698471550593e-12	12	0	0	148	10287
R-HSA-166786	Creation of C4 and C2 activators	0.999999999994353	-5.64698471550593e-12	12	0	0	148	10287
R-HSA-1236977	Endosomal/Vacuolar pathway	0.999999999994353	-5.64698471550593e-12	12	0	0	148	10287
R-HSA-622323	Presynaptic nicotinic acetylcholine receptors	0.999999999994353	-5.64698471550593e-12	12	0	0	148	10287
R-HSA-1234158	Regulation of gene expression by Hypoxia-inducible Factor	0.999999999994353	-5.64698471550593e-12	12	0	0	148	10287
R-HSA-844456	The NLRP3 inflammasome	0.999999999994353	-5.64698471550593e-12	12	0	0	148	10287
R-HSA-211979	Eicosanoids	0.999999999994353	-5.64698471550593e-12	12	0	0	148	10287
R-HSA-1474151	Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation	0.999999999994353	-5.64698471550593e-12	12	0	0	148	10287
R-HSA-5689877	Josephin domain DUBs	0.999999999994353	-5.64698471550593e-12	12	0	0	148	10287
R-HSA-389359	CD28 dependent Vav1 pathway	0.999999999994353	-5.64698471550593e-12	12	0	0	148	10287
R-HSA-6803207	TP53 Regulates Transcription of Caspase Activators and Caspases	0.999999999994353	-5.64698471550593e-12	12	0	0	148	10287
R-HSA-5250924	B-WICH complex positively regulates rRNA expression	0.999999999994359	-5.64094701924409e-12	93	0	0	148	10287
R-HSA-6804756	Regulation of TP53 Activity through Phosphorylation	0.999999999994359	-5.64094701924409e-12	93	0	0	148	10287
R-HSA-5625740	RHO GTPases activate PKNs	0.999999999994359	-5.64094701924409e-12	93	0	0	148	10287
R-HSA-5696399	Global Genome Nucleotide Excision Repair (GG-NER)	0.999999999994384	-5.61551896414353e-12	85	0	0	148	10287
R-HSA-5689603	UCH proteinases	0.999999999994707	-5.29290942759982e-12	105	0	0	148	10287
R-HSA-72689	Formation of a pool of free 40S subunits	0.999999999994707	-5.29290942759982e-12	105	0	0	148	10287
R-HSA-5693616	Presynaptic phase of homologous DNA pairing and strand exchange	0.99999999999476	-5.24004217481053e-12	40	0	0	148	10287
R-HSA-425397	Transport of vitamins, nucleosides, and related molecules	0.99999999999476	-5.24004217481053e-12	40	0	0	148	10287
R-HSA-1442490	Collagen degradation	0.99999999999476	-5.24004217481053e-12	40	0	0	148	10287
R-HSA-168276	NS1 Mediated Effects on Host Pathways	0.99999999999476	-5.24004217481053e-12	40	0	0	148	10287
R-HSA-5654741	Signaling by FGFR3	0.99999999999476	-5.24004217481053e-12	40	0	0	148	10287
R-HSA-2022377	Metabolism of Angiotensinogen to Angiotensins	0.999999999994784	-5.21592476442151e-12	18	0	0	148	10287
R-HSA-1839117	Signaling by cytosolic FGFR1 fusion mutants	0.999999999994784	-5.21592476442151e-12	18	0	0	148	10287
R-HSA-936964	Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon	0.999999999994784	-5.21592476442151e-12	18	0	0	148	10287
R-HSA-450385	Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA	0.999999999994784	-5.21592476442151e-12	18	0	0	148	10287
R-HSA-5654704	SHC-mediated cascade:FGFR3	0.999999999994784	-5.21592476442151e-12	18	0	0	148	10287
R-HSA-209776	Amine-derived hormones	0.999999999994784	-5.21592476442151e-12	18	0	0	148	10287
R-HSA-912631	Regulation of signaling by CBL	0.999999999994784	-5.21592476442151e-12	18	0	0	148	10287
R-HSA-196757	Metabolism of folate and pterines	0.999999999994784	-5.21592476442151e-12	18	0	0	148	10287
R-HSA-5635838	Activation of SMO	0.999999999994784	-5.21592476442151e-12	18	0	0	148	10287
R-HSA-5654710	PI-3K cascade:FGFR3	0.999999999994784	-5.21592476442151e-12	18	0	0	148	10287
R-HSA-418457	cGMP effects	0.999999999994784	-5.21592476442151e-12	18	0	0	148	10287
R-HSA-1912420	Pre-NOTCH Processing in Golgi	0.999999999994784	-5.21592476442151e-12	18	0	0	148	10287
R-HSA-69205	G1/S-Specific Transcription	0.999999999994784	-5.21592476442151e-12	18	0	0	148	10287
R-HSA-1482925	Acyl chain remodelling of PG	0.999999999994784	-5.21592476442151e-12	18	0	0	148	10287
R-HSA-73780	RNA Polymerase III Chain Elongation	0.999999999994784	-5.21592476442151e-12	18	0	0	148	10287
R-HSA-210993	Tie2 Signaling	0.999999999994784	-5.21592476442151e-12	18	0	0	148	10287
R-HSA-5654221	Phospholipase C-mediated cascade; FGFR2	0.999999999994784	-5.21592476442151e-12	18	0	0	148	10287
R-HSA-5676594	TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway	0.999999999994784	-5.21592476442151e-12	18	0	0	148	10287
R-HSA-450513	Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA	0.999999999994784	-5.21592476442151e-12	18	0	0	148	10287
R-HSA-1369062	ABC transporters in lipid homeostasis	0.999999999994784	-5.21592476442151e-12	18	0	0	148	10287
R-HSA-156581	Methylation	0.999999999995459	-4.5412535664237e-12	15	0	0	148	10287
R-HSA-2162123	Synthesis of Prostaglandins (PG) and Thromboxanes (TX)	0.999999999995459	-4.5412535664237e-12	15	0	0	148	10287
R-HSA-3322077	Glycogen synthesis	0.999999999995459	-4.5412535664237e-12	15	0	0	148	10287
R-HSA-430039	mRNA decay by 5' to 3' exoribonuclease	0.999999999995459	-4.5412535664237e-12	15	0	0	148	10287
R-HSA-2691232	Constitutive Signaling by NOTCH1 HD Domain Mutants	0.999999999995459	-4.5412535664237e-12	15	0	0	148	10287
R-HSA-8875360	InlB-mediated entry of Listeria monocytogenes into host cell	0.999999999995459	-4.5412535664237e-12	15	0	0	148	10287
R-HSA-68884	Mitotic Telophase/Cytokinesis	0.999999999995459	-4.5412535664237e-12	15	0	0	148	10287
R-HSA-5358751	S45 mutants of beta-catenin aren't phosphorylated	0.999999999995459	-4.5412535664237e-12	15	0	0	148	10287
R-HSA-193807	Synthesis of bile acids and bile salts via 27-hydroxycholesterol	0.999999999995459	-4.5412535664237e-12	15	0	0	148	10287
R-HSA-3134975	Regulation of innate immune responses to cytosolic DNA	0.999999999995459	-4.5412535664237e-12	15	0	0	148	10287
R-HSA-391903	Eicosanoid ligand-binding receptors	0.999999999995459	-4.5412535664237e-12	15	0	0	148	10287
R-HSA-5358747	S33 mutants of beta-catenin aren't phosphorylated	0.999999999995459	-4.5412535664237e-12	15	0	0	148	10287
R-HSA-111447	Activation of BAD and translocation to mitochondria	0.999999999995459	-4.5412535664237e-12	15	0	0	148	10287
R-HSA-4839743	phosphorylation site mutants of CTNNB1 are not targeted to the proteasome by the destruction complex	0.999999999995459	-4.5412535664237e-12	15	0	0	148	10287
R-HSA-205043	NRIF signals cell death from the nucleus	0.999999999995459	-4.5412535664237e-12	15	0	0	148	10287
R-HSA-5358752	T41 mutants of beta-catenin aren't phosphorylated	0.999999999995459	-4.5412535664237e-12	15	0	0	148	10287
R-HSA-6785631	ERBB2 Regulates Cell Motility	0.999999999995459	-4.5412535664237e-12	15	0	0	148	10287
R-HSA-975577	N-Glycan antennae elongation	0.999999999995459	-4.5412535664237e-12	15	0	0	148	10287
R-HSA-2691230	Signaling by NOTCH1 HD Domain Mutants in Cancer	0.999999999995459	-4.5412535664237e-12	15	0	0	148	10287
R-HSA-5358749	S37 mutants of beta-catenin aren't phosphorylated	0.999999999995459	-4.5412535664237e-12	15	0	0	148	10287
R-HSA-5654228	Phospholipase C-mediated cascade; FGFR4	0.999999999995459	-4.5412535664237e-12	15	0	0	148	10287
R-HSA-69298	Association of licensing factors with the pre-replicative complex	0.999999999995459	-4.5412535664237e-12	15	0	0	148	10287
R-HSA-5682910	LGI-ADAM interactions	0.999999999995459	-4.5412535664237e-12	15	0	0	148	10287
R-HSA-5339716	Misspliced GSK3beta mutants stabilize beta-catenin	0.999999999995459	-4.5412535664237e-12	15	0	0	148	10287
R-HSA-3772470	Negative regulation of TCF-dependent signaling by WNT ligand antagonists	0.999999999995459	-4.5412535664237e-12	15	0	0	148	10287
R-HSA-5358508	Mismatch Repair	0.999999999995459	-4.5412535664237e-12	15	0	0	148	10287
R-HSA-69183	Processive synthesis on the lagging strand	0.999999999995459	-4.5412535664237e-12	15	0	0	148	10287
R-HSA-192823	Viral mRNA Translation	0.99999999999556	-4.43982043616729e-12	92	0	0	148	10287
R-HSA-156902	Peptide chain elongation	0.99999999999556	-4.43982043616729e-12	92	0	0	148	10287
R-HSA-611105	Respiratory electron transport	0.99999999999556	-4.43982043616729e-12	92	0	0	148	10287
R-HSA-168330	Viral RNP Complexes in the Host Cell Nucleus	0.999999999995607	-4.39269627616756e-12	1	0	0	148	10287
R-HSA-6809583	Retinoid metabolism disease events	0.999999999995607	-4.39269627616756e-12	1	0	0	148	10287
R-HSA-1222499	Response of Mtb to phagocytosis	0.999999999995607	-4.39269627616756e-12	1	0	0	148	10287
R-HSA-5340573	WNT ligand secretion is abrogated by the PORCN inhibitor LGK974	0.999999999995607	-4.39269627616756e-12	1	0	0	148	10287
R-HSA-3359454	Defective TCN2 causes hereditary megaloblastic anemia	0.999999999995607	-4.39269627616756e-12	1	0	0	148	10287
R-HSA-5602410	TLR3 deficiency - HSE	0.999999999995607	-4.39269627616756e-12	1	0	0	148	10287
R-HSA-5083629	Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2	0.999999999995607	-4.39269627616756e-12	1	0	0	148	10287
R-HSA-389542	NADPH regeneration	0.999999999995607	-4.39269627616756e-12	1	0	0	148	10287
R-HSA-190840	Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane	0.999999999995607	-4.39269627616756e-12	1	0	0	148	10287
R-HSA-112122	ALKBH2 mediated reversal of alkylation damage	0.999999999995607	-4.39269627616756e-12	1	0	0	148	10287
R-HSA-1299344	TWIK-related spinal cord K+ channel (TRESK)	0.999999999995607	-4.39269627616756e-12	1	0	0	148	10287
R-HSA-1839128	FGFR4 mutant receptor activation	0.999999999995607	-4.39269627616756e-12	1	0	0	148	10287
R-HSA-163316	Mitochondrial transcription termination	0.999999999995607	-4.39269627616756e-12	1	0	0	148	10287
R-HSA-2534343	Interaction With Cumulus Cells	0.999999999995607	-4.39269627616756e-12	1	0	0	148	10287
R-HSA-3248023	Regulation by TREX1	0.999999999995607	-4.39269627616756e-12	1	0	0	148	10287
R-HSA-1222352	Latent infection of Homo sapiens with Mycobacterium tuberculosis	0.999999999995607	-4.39269627616756e-12	1	0	0	148	10287
R-HSA-169131	Inhibition of PKR	0.999999999995607	-4.39269627616756e-12	1	0	0	148	10287
R-HSA-1855231	Synthesis of IPs in the ER lumen	0.999999999995607	-4.39269627616756e-12	1	0	0	148	10287
R-HSA-5657655	MGMT-mediated DNA damage reversal	0.999999999995607	-4.39269627616756e-12	1	0	0	148	10287
R-HSA-162589	Reverse Transcription of HIV RNA	0.999999999995607	-4.39269627616756e-12	1	0	0	148	10287
R-HSA-211957	Aromatic amines can be N-hydroxylated or N-dealkylated by CYP1A2	0.999999999995607	-4.39269627616756e-12	1	0	0	148	10287
R-HSA-1299287	Tandem pore domain halothane-inhibited K+ channel (THIK)	0.999999999995607	-4.39269627616756e-12	1	0	0	148	10287
R-HSA-1483076	Synthesis of CL	0.999999999995607	-4.39269627616756e-12	1	0	0	148	10287
R-HSA-171286	Synthesis and processing of ENV and VPU	0.999999999995607	-4.39269627616756e-12	1	0	0	148	10287
R-HSA-3359474	Defective MMACHC causes methylmalonic aciduria and homocystinuria type cblC	0.999999999995607	-4.39269627616756e-12	1	0	0	148	10287
R-HSA-140180	COX reactions	0.999999999995607	-4.39269627616756e-12	1	0	0	148	10287
R-HSA-5083628	Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3	0.999999999995607	-4.39269627616756e-12	1	0	0	148	10287
R-HSA-5619058	Defective SLCO1B3 causes hyperbilirubinemia, Rotor type (HBLRR)	0.999999999995607	-4.39269627616756e-12	1	0	0	148	10287
R-HSA-8853333	Signaling by FGFR2 fusions	0.999999999995607	-4.39269627616756e-12	1	0	0	148	10287
R-HSA-162585	Uncoating of the HIV Virion	0.999999999995607	-4.39269627616756e-12	1	0	0	148	10287
R-HSA-164525	Plus-strand DNA synthesis	0.999999999995607	-4.39269627616756e-12	1	0	0	148	10287
R-HSA-5263617	Metabolism of ingested MeSeO2H into MeSeH	0.999999999995607	-4.39269627616756e-12	1	0	0	148	10287
R-HSA-5619110	Defective SLCO1B1 causes hyperbilirubinemia, Rotor type (HBLRR)	0.999999999995607	-4.39269627616756e-12	1	0	0	148	10287
R-HSA-1839120	Signaling by FGFR1 amplification mutants	0.999999999995607	-4.39269627616756e-12	1	0	0	148	10287
R-HSA-164516	Minus-strand DNA synthesis	0.999999999995607	-4.39269627616756e-12	1	0	0	148	10287
R-HSA-5250982	Toxicity of tetanus toxin (TeNT)	0.999999999995607	-4.39269627616756e-12	1	0	0	148	10287
R-HSA-5083633	Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1	0.999999999995607	-4.39269627616756e-12	1	0	0	148	10287
R-HSA-2023837	Signaling by FGFR2 amplification mutants	0.999999999995607	-4.39269627616756e-12	1	0	0	148	10287
R-HSA-2466712	Biosynthesis of A2E, implicated in retinal degradation	0.999999999995607	-4.39269627616756e-12	1	0	0	148	10287
R-HSA-1222449	Mtb iron assimilation by chelation	0.999999999995607	-4.39269627616756e-12	1	0	0	148	10287
R-HSA-1300645	Acrosome Reaction	0.999999999995607	-4.39269627616756e-12	1	0	0	148	10287
R-HSA-5467333	APC truncation mutants are not K63 polyubiquitinated	0.999999999995607	-4.39269627616756e-12	1	0	0	148	10287
R-HSA-2408552	Methylation of MeSeH for excretion	0.999999999995607	-4.39269627616756e-12	1	0	0	148	10287
R-HSA-3359457	Defective GIF causes intrinsic factor deficiency	0.999999999995607	-4.39269627616756e-12	1	0	0	148	10287
R-HSA-975574	Reactions specific to the hybrid N-glycan synthesis pathway	0.999999999995607	-4.39269627616756e-12	1	0	0	148	10287
R-HSA-2978092	Abnormal conversion of 2-oxoglutarate to 2-hydroxyglutarate	0.999999999995607	-4.39269627616756e-12	1	0	0	148	10287
R-HSA-2142696	Synthesis of Hepoxilins (HX) and Trioxilins (TrX)	0.999999999995607	-4.39269627616756e-12	1	0	0	148	10287
R-HSA-1483196	PI and PC transport between ER and Golgi membranes	0.999999999995607	-4.39269627616756e-12	1	0	0	148	10287
R-HSA-5602415	UNC93B1 deficiency - HSE	0.999999999995607	-4.39269627616756e-12	1	0	0	148	10287
R-HSA-2033515	t(4;14) translocations of FGFR3	0.999999999995607	-4.39269627616756e-12	1	0	0	148	10287
R-HSA-432720	Lysosome Vesicle Biogenesis	0.999999999995681	-4.31866233369414e-12	36	0	0	148	10287
R-HSA-452723	Transcriptional regulation of pluripotent stem cells	0.999999999995681	-4.31866233369414e-12	36	0	0	148	10287
R-HSA-532668	N-glycan trimming in the ER and Calnexin/Calreticulin cycle	0.999999999995681	-4.31866233369414e-12	36	0	0	148	10287
R-HSA-5663213	RHO GTPases Activate WASPs and WAVEs	0.999999999995681	-4.31866233369414e-12	36	0	0	148	10287
R-HSA-76046	RNA Polymerase III Transcription Initiation	0.999999999995681	-4.31866233369414e-12	36	0	0	148	10287
R-HSA-177243	Interactions of Rev with host cellular proteins	0.999999999995681	-4.31866233369414e-12	36	0	0	148	10287
R-HSA-176033	Interactions of Vpr with host cellular proteins	0.999999999995681	-4.31866233369414e-12	36	0	0	148	10287
R-HSA-936440	Negative regulators of RIG-I/MDA5 signaling	0.999999999995681	-4.31866233369414e-12	36	0	0	148	10287
R-HSA-69300	Removal of licensing factors from origins	0.999999999995799	-4.20083628854223e-12	74	0	0	148	10287
R-HSA-212300	PRC2 methylates histones and DNA	0.999999999995799	-4.20083628854223e-12	74	0	0	148	10287
R-HSA-2299718	Condensation of Prophase Chromosomes	0.999999999995799	-4.20083628854223e-12	74	0	0	148	10287
R-HSA-179419	APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint	0.999999999995799	-4.20083628854223e-12	74	0	0	148	10287
R-HSA-73777	RNA Polymerase I Chain Elongation	0.999999999995929	-4.07085221596288e-12	91	0	0	148	10287
R-HSA-2565942	Regulation of PLK1 Activity at G2/M Transition	0.999999999996143	-3.85678205806903e-12	90	0	0	148	10287
R-HSA-2219528	PI3K/AKT Signaling in Cancer	0.999999999996143	-3.85678205806903e-12	90	0	0	148	10287
R-HSA-428157	Sphingolipid metabolism	0.999999999996143	-3.85678205806903e-12	90	0	0	148	10287
R-HSA-5696395	Formation of Incision Complex in GG-NER	0.999999999996744	-3.25611654033179e-12	43	0	0	148	10287
R-HSA-75893	TNF signaling	0.999999999996744	-3.25611654033179e-12	43	0	0	148	10287
R-HSA-5693579	Homologous DNA Pairing and Strand Exchange	0.999999999996744	-3.25611654033179e-12	43	0	0	148	10287
R-HSA-375280	Amine ligand-binding receptors	0.999999999996744	-3.25611654033179e-12	43	0	0	148	10287
R-HSA-194068	Bile acid and bile salt metabolism	0.999999999996744	-3.25611654033179e-12	43	0	0	148	10287
R-HSA-1236394	Signaling by ERBB4	0.999999999996744	-3.25611654033179e-12	43	0	0	148	10287
R-HSA-2173782	Binding and Uptake of Ligands by Scavenger Receptors	0.999999999996744	-3.25611654033179e-12	43	0	0	148	10287
R-HSA-198933	Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell	0.99999999999676	-3.2402441297686e-12	124	0	0	148	10287
R-HSA-2500257	Resolution of Sister Chromatid Cohesion	0.999999999997022	-2.97754570045934e-12	103	0	0	148	10287
R-HSA-72306	tRNA processing	0.999999999997116	-2.88410925887034e-12	109	0	0	148	10287
R-HSA-73886	Chromosome Maintenance	0.999999999997116	-2.88410925887034e-12	109	0	0	148	10287
R-HSA-69306	DNA Replication	0.999999999997116	-2.88410925887034e-12	109	0	0	148	10287
R-HSA-68881	Mitotic Metaphase/Anaphase Transition	0.999999999997384	-2.6155998211503e-12	2	0	0	148	10287
R-HSA-205017	NFG and proNGF binds to p75NTR	0.999999999997384	-2.6155998211503e-12	2	0	0	148	10287
R-HSA-1483152	Hydrolysis of LPE	0.999999999997384	-2.6155998211503e-12	2	0	0	148	10287
R-HSA-5683177	Defective ABCC8 can cause hypoglycemias and hyperglycemias	0.999999999997384	-2.6155998211503e-12	2	0	0	148	10287
R-HSA-168277	Influenza Virus Induced Apoptosis	0.999999999997384	-2.6155998211503e-12	2	0	0	148	10287
R-HSA-168268	Virus Assembly and Release	0.999999999997384	-2.6155998211503e-12	2	0	0	148	10287
R-HSA-1483101	Synthesis of PS	0.999999999997384	-2.6155998211503e-12	2	0	0	148	10287
R-HSA-192905	vRNP Assembly	0.999999999997384	-2.6155998211503e-12	2	0	0	148	10287
R-HSA-211728	Regulation of PAK-2p34 activity by PS-GAP/RHG10	0.999999999997384	-2.6155998211503e-12	2	0	0	148	10287
R-HSA-1299361	TWIK-related alkaline pH activated K+ channel (TALK)	0.999999999997384	-2.6155998211503e-12	2	0	0	148	10287
R-HSA-177162	Conjugation of phenylacetate with glutamine	0.999999999997384	-2.6155998211503e-12	2	0	0	148	10287
R-HSA-5652227	Fructose biosynthesis	0.999999999997384	-2.6155998211503e-12	2	0	0	148	10287
R-HSA-3359469	Defective MTR causes methylmalonic aciduria and homocystinuria type cblG	0.999999999997384	-2.6155998211503e-12	2	0	0	148	10287
R-HSA-5579031	Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD)	0.999999999997384	-2.6155998211503e-12	2	0	0	148	10287
R-HSA-141334	PAOs oxidise polyamines to amines	0.999999999997384	-2.6155998211503e-12	2	0	0	148	10287
R-HSA-3828062	Glycogen storage disease type 0 (muscle GYS1)	0.999999999997384	-2.6155998211503e-12	2	0	0	148	10287
R-HSA-75102	C6 deamination of adenosine	0.999999999997384	-2.6155998211503e-12	2	0	0	148	10287
R-HSA-844623	The IPAF inflammasome	0.999999999997384	-2.6155998211503e-12	2	0	0	148	10287
R-HSA-71737	Pyrophosphate hydrolysis	0.999999999997384	-2.6155998211503e-12	2	0	0	148	10287
R-HSA-5545619	XAV939 inhibits tankyrase, stabilizing AXIN	0.999999999997384	-2.6155998211503e-12	2	0	0	148	10287
R-HSA-480985	Synthesis of dolichyl-phosphate-glucose	0.999999999997384	-2.6155998211503e-12	2	0	0	148	10287
R-HSA-1614603	Cysteine formation from homocysteine	0.999999999997384	-2.6155998211503e-12	2	0	0	148	10287
R-HSA-5638303	Inhibition of Signaling by Overexpressed EGFR	0.999999999997384	-2.6155998211503e-12	2	0	0	148	10287
R-HSA-380612	Metabolism of serotonin	0.999999999997384	-2.6155998211503e-12	2	0	0	148	10287
R-HSA-75064	mRNA Editing: A to I Conversion	0.999999999997384	-2.6155998211503e-12	2	0	0	148	10287
R-HSA-164939	Nef mediated downregulation of CD28 cell surface expression	0.999999999997384	-2.6155998211503e-12	2	0	0	148	10287
R-HSA-168275	Entry of Influenza Virion into Host Cell via Endocytosis	0.999999999997384	-2.6155998211503e-12	2	0	0	148	10287
R-HSA-156582	Acetylation	0.999999999997384	-2.6155998211503e-12	2	0	0	148	10287
R-HSA-1299316	TWIK-releated acid-sensitive K+ channel (TASK)	0.999999999997384	-2.6155998211503e-12	2	0	0	148	10287
R-HSA-141424	Amplification of signal from the kinetochores	0.999999999997384	-2.6155998211503e-12	2	0	0	148	10287
R-HSA-3642279	TGFBR2 MSI Frameshift Mutants in Cancer	0.999999999997384	-2.6155998211503e-12	2	0	0	148	10287
R-HSA-141444	Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal	0.999999999997384	-2.6155998211503e-12	2	0	0	148	10287
R-HSA-888568	GABA synthesis	0.999999999997384	-2.6155998211503e-12	2	0	0	148	10287
R-HSA-75896	Plasmalogen biosynthesis	0.999999999997384	-2.6155998211503e-12	2	0	0	148	10287
R-HSA-190872	Transport of connexons to the plasma membrane	0.999999999997384	-2.6155998211503e-12	2	0	0	148	10287
R-HSA-5687868	Defective SFTPA2 causes idiopathic pulmonary fibrosis (IPF)	0.999999999997384	-2.6155998211503e-12	2	0	0	148	10287
R-HSA-111457	Release of apoptotic factors from the mitochondria	0.999999999997384	-2.6155998211503e-12	2	0	0	148	10287
R-HSA-168316	Assembly of Viral Components at the Budding Site	0.999999999997384	-2.6155998211503e-12	2	0	0	148	10287
R-HSA-428559	Proton-coupled neutral amino acid transporters	0.999999999997384	-2.6155998211503e-12	2	0	0	148	10287
R-HSA-211994	Sterols are 12-hydroxylated by CYP8B1	0.999999999997384	-2.6155998211503e-12	2	0	0	148	10287
R-HSA-165160	PDE3B signalling	0.999999999997384	-2.6155998211503e-12	2	0	0	148	10287
R-HSA-5688354	Defective pro-SFTPC causes pulmonary surfactant metabolism dysfunction 2 (SMDP2) and respiratory distress syndrome (RDS)	0.999999999997384	-2.6155998211503e-12	2	0	0	148	10287
R-HSA-3359467	Defective MTRR causes methylmalonic aciduria and homocystinuria type cblE	0.999999999997384	-2.6155998211503e-12	2	0	0	148	10287
R-HSA-203754	NOSIP mediated eNOS trafficking	0.999999999997384	-2.6155998211503e-12	2	0	0	148	10287
R-HSA-3359478	Defective MUT causes methylmalonic aciduria mut type	0.999999999997384	-2.6155998211503e-12	2	0	0	148	10287
R-HSA-5357609	Glycogen storage disease type II (GAA)	0.999999999997384	-2.6155998211503e-12	2	0	0	148	10287
R-HSA-198765	Signalling to ERK5	0.999999999997384	-2.6155998211503e-12	2	0	0	148	10287
R-HSA-351143	Agmatine biosynthesis	0.999999999997384	-2.6155998211503e-12	2	0	0	148	10287
R-HSA-70688	Proline catabolism	0.999999999997384	-2.6155998211503e-12	2	0	0	148	10287
R-HSA-3359475	Defective MMAA causes methylmalonic aciduria type cblA	0.999999999997384	-2.6155998211503e-12	2	0	0	148	10287
R-HSA-8942233	Intestinal infectious diseases	0.999999999997384	-2.6155998211503e-12	2	0	0	148	10287
R-HSA-114294	Activation, translocation and oligomerization of BAX	0.999999999997384	-2.6155998211503e-12	2	0	0	148	10287
R-HSA-211736	Stimulation of the cell death response by PAK-2p34	0.999999999997384	-2.6155998211503e-12	2	0	0	148	10287
R-HSA-187042	TRKA activation by NGF	0.999999999997384	-2.6155998211503e-12	2	0	0	148	10287
R-HSA-166020	Transfer of LPS from LBP carrier to CD14	0.999999999997384	-2.6155998211503e-12	2	0	0	148	10287
R-HSA-3814836	Glycogen storage disease type XV (GYG1)	0.999999999997384	-2.6155998211503e-12	2	0	0	148	10287
R-HSA-141333	Biogenic amines are oxidatively deaminated to aldehydes by MAOA and MAOB	0.999999999997384	-2.6155998211503e-12	2	0	0	148	10287
R-HSA-168315	Inhibition of Host mRNA Processing and RNA Silencing	0.999999999997384	-2.6155998211503e-12	2	0	0	148	10287
R-HSA-5602566	TICAM1 deficiency - HSE	0.999999999997384	-2.6155998211503e-12	2	0	0	148	10287
R-HSA-5602636	IKBKB deficiency causes SCID	0.999999999997384	-2.6155998211503e-12	2	0	0	148	10287
R-HSA-73930	Abasic sugar-phosphate removal via the single-nucleotide replacement pathway	0.999999999997384	-2.6155998211503e-12	2	0	0	148	10287
R-HSA-3359485	Defective CD320 causes methylmalonic aciduria	0.999999999997384	-2.6155998211503e-12	2	0	0	148	10287
R-HSA-8854521	Interaction between PHLDA1 and AURKA	0.999999999997384	-2.6155998211503e-12	2	0	0	148	10287
R-HSA-3359473	Defective MMADHC causes methylmalonic aciduria and homocystinuria type cblD	0.999999999997384	-2.6155998211503e-12	2	0	0	148	10287
R-HSA-8849175	Threonine catabolism	0.999999999997384	-2.6155998211503e-12	2	0	0	148	10287
R-HSA-5619107	Defective TRP may confer susceptibility towards thyroid papillary carcinoma (TPC)	0.999999999997384	-2.6155998211503e-12	2	0	0	148	10287
R-HSA-111995	phospho-PLA2 pathway	0.999999999997384	-2.6155998211503e-12	2	0	0	148	10287
R-HSA-451307	Activation of Na-permeable Kainate Receptors	0.999999999997384	-2.6155998211503e-12	2	0	0	148	10287
R-HSA-77042	Formation of editosomes by ADAR proteins	0.999999999997384	-2.6155998211503e-12	2	0	0	148	10287
R-HSA-3858516	Glycogen storage disease type 0 (liver GYS2)	0.999999999997384	-2.6155998211503e-12	2	0	0	148	10287
R-HSA-432030	Transport of glycerol from adipocytes to the liver by Aquaporins	0.999999999997384	-2.6155998211503e-12	2	0	0	148	10287
R-HSA-163754	Insulin effects increased synthesis of Xylulose-5-Phosphate	0.999999999997384	-2.6155998211503e-12	2	0	0	148	10287
R-HSA-111452	Activation and oligomerization of BAK protein	0.999999999997384	-2.6155998211503e-12	2	0	0	148	10287
R-HSA-5638302	Signaling by Overexpressed Wild-Type EGFR in Cancer	0.999999999997384	-2.6155998211503e-12	2	0	0	148	10287
R-HSA-162909	Host Interactions of HIV factors	0.999999999997696	-2.30452874407591e-12	134	0	0	148	10287
R-HSA-202424	Downstream TCR signaling	0.999999999997996	-2.00438410377302e-12	98	0	0	148	10287
R-HSA-5693607	Processing of DNA double-strand break ends	0.999999999997996	-2.00438410377302e-12	98	0	0	148	10287
R-HSA-68949	Orc1 removal from chromatin	0.999999999998159	-1.84144549700524e-12	72	0	0	148	10287
R-HSA-606279	Deposition of new CENPA-containing nucleosomes at the centromere	0.999999999998159	-1.84144549700524e-12	72	0	0	148	10287
R-HSA-69052	Switching of origins to a post-replicative state	0.999999999998159	-1.84144549700524e-12	72	0	0	148	10287
R-HSA-380259	Loss of Nlp from mitotic centrosomes	0.999999999998159	-1.84144549700524e-12	72	0	0	148	10287
R-HSA-380284	Loss of proteins required for interphase microtubule organization from the centrosome	0.999999999998159	-1.84144549700524e-12	72	0	0	148	10287
R-HSA-774815	Nucleosome assembly	0.999999999998159	-1.84144549700524e-12	72	0	0	148	10287
R-HSA-5578749	Transcriptional regulation by small RNAs	0.999999999998445	-1.55525142491213e-12	106	0	0	148	10287
R-HSA-156580	Phase II conjugation	0.999999999998445	-1.55525142491213e-12	106	0	0	148	10287
R-HSA-2408557	Selenocysteine synthesis	0.999999999998612	-1.38758603498342e-12	95	0	0	148	10287
R-HSA-69473	G2/M DNA damage checkpoint	0.999999999998612	-1.38758603498342e-12	95	0	0	148	10287
R-HSA-8854050	FBXL7 down-regulates AURKA during mitotic entry and in early mitosis	0.99999999999881	-1.19013749480922e-12	56	0	0	148	10287
R-HSA-174113	SCF-beta-TrCP mediated degradation of Emi1	0.99999999999881	-1.19013749480922e-12	56	0	0	148	10287
R-HSA-4641257	Degradation of AXIN	0.99999999999881	-1.19013749480922e-12	56	0	0	148	10287
R-HSA-69541	Stabilization of p53	0.99999999999881	-1.19013749480922e-12	56	0	0	148	10287
R-HSA-163200	Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.	0.999999999998977	-1.02322125171205e-12	113	0	0	148	10287
R-HSA-5693565	Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks	0.999999999999134	-8.66463734534399e-13	75	0	0	148	10287
R-HSA-8854518	AURKA Activation by TPX2	0.999999999999134	-8.66463734534399e-13	75	0	0	148	10287
R-HSA-159236	Transport of Mature mRNA derived from an Intron-Containing Transcript	0.999999999999134	-8.66463734534399e-13	75	0	0	148	10287
R-HSA-191859	snRNP Assembly	0.999999999999267	-7.32808584924535e-13	53	0	0	148	10287
R-HSA-194441	Metabolism of non-coding RNA	0.999999999999267	-7.32808584924535e-13	53	0	0	148	10287
R-HSA-6806667	Metabolism of fat-soluble vitamins	0.999999999999267	-7.32808584924535e-13	53	0	0	148	10287
R-HSA-180534	Vpu mediated degradation of CD4	0.999999999999267	-7.32808584924535e-13	53	0	0	148	10287
R-HSA-72695	Formation of the ternary complex, and subsequently, the 43S complex	0.999999999999267	-7.32808584924535e-13	53	0	0	148	10287
R-HSA-5620920	Cargo trafficking to the periciliary membrane	0.999999999999267	-7.32808584924535e-13	53	0	0	148	10287
R-HSA-349425	Autodegradation of the E3 ubiquitin ligase COP1	0.999999999999267	-7.32808584924535e-13	53	0	0	148	10287
R-HSA-5661231	Metallothioneins bind metals	0.99999999999952	-4.79949675343838e-13	11	0	0	148	10287
R-HSA-2022923	Dermatan sulfate biosynthesis	0.99999999999952	-4.79949675343838e-13	11	0	0	148	10287
R-HSA-71182	Phenylalanine and tyrosine catabolism	0.99999999999952	-4.79949675343838e-13	11	0	0	148	10287
R-HSA-380320	Recruitment of NuMA to mitotic centrosomes	0.99999999999952	-4.79949675343838e-13	11	0	0	148	10287
R-HSA-5625970	RHO GTPases activate KTN1	0.99999999999952	-4.79949675343838e-13	11	0	0	148	10287
R-HSA-975144	IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation	0.99999999999952	-4.79949675343838e-13	11	0	0	148	10287
R-HSA-196780	Biotin transport and metabolism	0.99999999999952	-4.79949675343838e-13	11	0	0	148	10287
R-HSA-75072	mRNA Editing	0.99999999999952	-4.79949675343838e-13	11	0	0	148	10287
R-HSA-71288	Creatine metabolism	0.99999999999952	-4.79949675343838e-13	11	0	0	148	10287
R-HSA-2485179	Activation of the phototransduction cascade	0.99999999999952	-4.79949675343838e-13	11	0	0	148	10287
R-HSA-68689	CDC6 association with the ORC:origin complex	0.99999999999952	-4.79949675343838e-13	11	0	0	148	10287
R-HSA-5685939	HDR through MMEJ (alt-NHEJ)	0.99999999999952	-4.79949675343838e-13	11	0	0	148	10287
R-HSA-3371378	Regulation by c-FLIP	0.99999999999952	-4.79949675343838e-13	11	0	0	148	10287
R-HSA-1980148	Signaling by NOTCH3	0.99999999999952	-4.79949675343838e-13	11	0	0	148	10287
R-HSA-351906	Apoptotic cleavage of cell adhesion  proteins	0.99999999999952	-4.79949675343838e-13	11	0	0	148	10287
R-HSA-937039	IRAK1 recruits IKK complex	0.99999999999952	-4.79949675343838e-13	11	0	0	148	10287
R-HSA-5218900	CASP8 activity is inhibited	0.99999999999952	-4.79949675343838e-13	11	0	0	148	10287
R-HSA-2470946	Cohesin Loading onto Chromatin	0.99999999999952	-4.79949675343838e-13	11	0	0	148	10287
R-HSA-174414	Processive synthesis on the C-strand of the telomere	0.99999999999952	-4.79949675343838e-13	11	0	0	148	10287
R-HSA-549127	Organic cation transport	0.99999999999952	-4.79949675343838e-13	11	0	0	148	10287
R-HSA-73614	Pyrimidine salvage reactions	0.99999999999952	-4.79949675343838e-13	11	0	0	148	10287
R-HSA-1059683	Interleukin-6 signaling	0.99999999999952	-4.79949675343838e-13	11	0	0	148	10287
R-HSA-5660526	Response to metal ions	0.99999999999952	-4.79949675343838e-13	11	0	0	148	10287
R-HSA-8851805	MET activates RAS signaling	0.99999999999952	-4.79949675343838e-13	11	0	0	148	10287
R-HSA-174490	Membrane binding and targetting of GAG proteins	0.99999999999952	-4.79949675343838e-13	11	0	0	148	10287
R-HSA-200425	Import of palmitoyl-CoA into the mitochondrial matrix	0.99999999999952	-4.79949675343838e-13	11	0	0	148	10287
R-HSA-3296469	Defects in cobalamin (B12) metabolism	0.99999999999952	-4.79949675343838e-13	11	0	0	148	10287
R-HSA-211999	CYP2E1 reactions	0.99999999999952	-4.79949675343838e-13	11	0	0	148	10287
R-HSA-174495	Synthesis And Processing Of GAG, GAGPOL Polyproteins	0.99999999999952	-4.79949675343838e-13	11	0	0	148	10287
R-HSA-629594	Highly calcium permeable postsynaptic nicotinic acetylcholine receptors	0.99999999999952	-4.79949675343838e-13	11	0	0	148	10287
R-HSA-446107	Type I hemidesmosome assembly	0.99999999999952	-4.79949675343838e-13	11	0	0	148	10287
R-HSA-193048	Androgen biosynthesis	0.99999999999952	-4.79949675343838e-13	11	0	0	148	10287
R-HSA-5655291	Signaling by FGFR4 in disease	0.99999999999952	-4.79949675343838e-13	11	0	0	148	10287
R-HSA-69416	Dimerization of procaspase-8	0.99999999999952	-4.79949675343838e-13	11	0	0	148	10287
R-HSA-1855183	Synthesis of IP2, IP, and Ins in the cytosol	0.99999999999952	-4.79949675343838e-13	11	0	0	148	10287
R-HSA-2514853	Condensation of Prometaphase Chromosomes	0.99999999999952	-4.79949675343838e-13	11	0	0	148	10287
R-HSA-1839122	Signaling by activated point mutants of FGFR1	0.99999999999952	-4.79949675343838e-13	11	0	0	148	10287
R-HSA-418889	Ligand-independent caspase activation via DCC	0.99999999999952	-4.79949675343838e-13	11	0	0	148	10287
R-HSA-8875555	MET activates RAP1 and RAC1	0.99999999999952	-4.79949675343838e-13	11	0	0	148	10287
R-HSA-1980150	Signaling by NOTCH4	0.99999999999952	-4.79949675343838e-13	11	0	0	148	10287
R-HSA-69620	Cell Cycle Checkpoints	0.999999999999649	-3.51267794224349e-13	201	0	0	148	10287
R-HSA-72312	rRNA processing	0.999999999999649	-3.51267794224349e-13	201	0	0	148	10287
R-HSA-936837	Ion transport by P-type ATPases	1.00000000000011	1.06509420909177e-13	58	0	0	148	10287
R-HSA-5362768	Hh mutants that don't undergo autocatalytic processing are degraded by ERAD	1.00000000000011	1.06509420909177e-13	58	0	0	148	10287
R-HSA-1799339	SRP-dependent cotranslational protein targeting to membrane	1.00000000000012	1.16191630215189e-13	115	0	0	148	10287
R-HSA-927802	Nonsense-Mediated Decay (NMD)	1.00000000000088	8.76596726345899e-13	120	0	0	148	10287
R-HSA-975957	Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)	1.00000000000088	8.76596726345899e-13	120	0	0	148	10287
R-HSA-5696398	Nucleotide Excision Repair	1.00000000000103	1.02789760905165e-12	112	0	0	148	10287
R-HSA-73864	RNA Polymerase I Transcription	1.00000000000103	1.02789760905165e-12	112	0	0	148	10287
R-HSA-70350	Fructose catabolism	1.00000000000171	1.71126322345834e-12	5	0	0	148	10287
R-HSA-390648	Muscarinic acetylcholine receptors	1.00000000000171	1.71126322345834e-12	5	0	0	148	10287
R-HSA-77310	Beta oxidation of lauroyl-CoA to decanoyl-CoA-CoA	1.00000000000171	1.71126322345834e-12	5	0	0	148	10287
R-HSA-5683678	Defective ABCA3 causes pulmonary surfactant metabolism dysfunction type 3 (SMDP3)	1.00000000000171	1.71126322345834e-12	5	0	0	148	10287
R-HSA-71262	Carnitine synthesis	1.00000000000171	1.71126322345834e-12	5	0	0	148	10287
R-HSA-111932	CaMK IV-mediated phosphorylation of CREB	1.00000000000171	1.71126322345834e-12	5	0	0	148	10287
R-HSA-3642278	Loss of Function of TGFBR2 in Cancer	1.00000000000171	1.71126322345834e-12	5	0	0	148	10287
R-HSA-3645790	TGFBR2 Kinase Domain Mutants in Cancer	1.00000000000171	1.71126322345834e-12	5	0	0	148	10287
R-HSA-140834	Extrinsic Pathway of Fibrin Clot Formation	1.00000000000171	1.71126322345834e-12	5	0	0	148	10287
R-HSA-8849468	PTK6 Regulates Proteins Involved in RNA Processing	1.00000000000171	1.71126322345834e-12	5	0	0	148	10287
R-HSA-75157	FasL/ CD95L signaling	1.00000000000171	1.71126322345834e-12	5	0	0	148	10287
R-HSA-2161541	Abacavir metabolism	1.00000000000171	1.71126322345834e-12	5	0	0	148	10287
R-HSA-3000471	Scavenging by Class B Receptors	1.00000000000171	1.71126322345834e-12	5	0	0	148	10287
R-HSA-3656535	TGFBR1 LBD Mutants in Cancer	1.00000000000171	1.71126322345834e-12	5	0	0	148	10287
R-HSA-77346	Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA	1.00000000000171	1.71126322345834e-12	5	0	0	148	10287
R-HSA-446205	Synthesis of GDP-mannose	1.00000000000171	1.71126322345834e-12	5	0	0	148	10287
R-HSA-74713	IRS activation	1.00000000000171	1.71126322345834e-12	5	0	0	148	10287
R-HSA-167827	The proton buffering model	1.00000000000171	1.71126322345834e-12	5	0	0	148	10287
R-HSA-1300652	Sperm:Oocyte Membrane Binding	1.00000000000171	1.71126322345834e-12	5	0	0	148	10287
R-HSA-2161517	Abacavir transmembrane transport	1.00000000000171	1.71126322345834e-12	5	0	0	148	10287
R-HSA-111464	SMAC-mediated dissociation of IAP:caspase complexes	1.00000000000171	1.71126322345834e-12	5	0	0	148	10287
R-HSA-163358	PKA-mediated phosphorylation of key metabolic factors	1.00000000000171	1.71126322345834e-12	5	0	0	148	10287
R-HSA-444209	Free fatty acid receptors	1.00000000000171	1.71126322345834e-12	5	0	0	148	10287
R-HSA-1614517	Sulfide oxidation to sulfate	1.00000000000171	1.71126322345834e-12	5	0	0	148	10287
R-HSA-2142850	Hyaluronan biosynthesis and export	1.00000000000171	1.71126322345834e-12	5	0	0	148	10287
R-HSA-5250981	Toxicity of botulinum toxin type F (BoNT/F)	1.00000000000171	1.71126322345834e-12	5	0	0	148	10287
R-HSA-77348	Beta oxidation of octanoyl-CoA to hexanoyl-CoA	1.00000000000171	1.71126322345834e-12	5	0	0	148	10287
R-HSA-210746	Regulation of gene expression in endocrine-committed (NEUROG3+) progenitor cells	1.00000000000171	1.71126322345834e-12	5	0	0	148	10287
R-HSA-70370	Galactose catabolism	1.00000000000171	1.71126322345834e-12	5	0	0	148	10287
R-HSA-8852405	Signaling by MST1	1.00000000000171	1.71126322345834e-12	5	0	0	148	10287
R-HSA-77352	Beta oxidation of butanoyl-CoA to acetyl-CoA	1.00000000000171	1.71126322345834e-12	5	0	0	148	10287
R-HSA-166187	Mitochondrial Uncoupling Proteins	1.00000000000171	1.71126322345834e-12	5	0	0	148	10287
R-HSA-427652	Sodium-coupled phosphate cotransporters	1.00000000000171	1.71126322345834e-12	5	0	0	148	10287
R-HSA-390651	Dopamine receptors	1.00000000000171	1.71126322345834e-12	5	0	0	148	10287
R-HSA-1606341	IRF3 mediated activation of type 1 IFN	1.00000000000171	1.71126322345834e-12	5	0	0	148	10287
R-HSA-1306955	GRB7 events in ERBB2 signaling	1.00000000000171	1.71126322345834e-12	5	0	0	148	10287
R-HSA-77350	Beta oxidation of hexanoyl-CoA to butanoyl-CoA	1.00000000000171	1.71126322345834e-12	5	0	0	148	10287
R-HSA-71032	Propionyl-CoA catabolism	1.00000000000171	1.71126322345834e-12	5	0	0	148	10287
R-HSA-187024	NGF-independant TRKA activation	1.00000000000171	1.71126322345834e-12	5	0	0	148	10287
R-HSA-180689	APOBEC3G mediated resistance to HIV-1 infection	1.00000000000171	1.71126322345834e-12	5	0	0	148	10287
R-HSA-111461	Cytochrome c-mediated apoptotic response	1.00000000000171	1.71126322345834e-12	5	0	0	148	10287
R-HSA-5250955	Toxicity of botulinum toxin type D (BoNT/D)	1.00000000000171	1.71126322345834e-12	5	0	0	148	10287
R-HSA-964739	N-glycan trimming and elongation in the cis-Golgi	1.00000000000171	1.71126322345834e-12	5	0	0	148	10287
R-HSA-8869496	TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation	1.00000000000171	1.71126322345834e-12	5	0	0	148	10287
R-HSA-2855086	Ficolins bind to repetitive carbohydrate structures on the target cell surface	1.00000000000171	1.71126322345834e-12	5	0	0	148	10287
R-HSA-380095	Tachykinin receptors bind tachykinins	1.00000000000171	1.71126322345834e-12	5	0	0	148	10287
R-HSA-8853383	Lysosomal oligosaccharide catabolism	1.00000000000171	1.71126322345834e-12	5	0	0	148	10287
R-HSA-2644607	Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling	1.00000000000171	1.71126322345834e-12	5	0	0	148	10287
R-HSA-389599	Alpha-oxidation of phytanate	1.00000000000171	1.71126322345834e-12	5	0	0	148	10287
R-HSA-157881	Cyclin B2 mediated events	1.00000000000171	1.71126322345834e-12	5	0	0	148	10287
R-HSA-6785470	tRNA processing in the mitochondrion	1.00000000000171	1.71126322345834e-12	5	0	0	148	10287
R-HSA-111463	SMAC binds to IAPs	1.00000000000171	1.71126322345834e-12	5	0	0	148	10287
R-HSA-112303	Electric Transmission Across Gap Junctions	1.00000000000171	1.71126322345834e-12	5	0	0	148	10287
R-HSA-561048	Organic anion transport	1.00000000000171	1.71126322345834e-12	5	0	0	148	10287
R-HSA-69478	G2/M DNA replication checkpoint	1.00000000000171	1.71126322345834e-12	5	0	0	148	10287
R-HSA-433137	Sodium-coupled sulphate, di- and tri-carboxylate transporters	1.00000000000171	1.71126322345834e-12	5	0	0	148	10287
R-HSA-111459	Activation of caspases through apoptosome-mediated cleavage	1.00000000000171	1.71126322345834e-12	5	0	0	148	10287
R-HSA-2644605	FBXW7 Mutants and NOTCH1 in Cancer	1.00000000000171	1.71126322345834e-12	5	0	0	148	10287
R-HSA-8866423	VLDL biosynthesis	1.00000000000171	1.71126322345834e-12	5	0	0	148	10287
R-HSA-391906	Leukotriene receptors	1.00000000000171	1.71126322345834e-12	5	0	0	148	10287
R-HSA-196819	Vitamin B1 (thiamin) metabolism	1.00000000000171	1.71126322345834e-12	5	0	0	148	10287
R-HSA-203641	NOSTRIN mediated eNOS trafficking	1.00000000000171	1.71126322345834e-12	5	0	0	148	10287
R-HSA-68911	G2 Phase	1.00000000000171	1.71126322345834e-12	5	0	0	148	10287
R-HSA-8866376	Reelin signalling pathway	1.00000000000171	1.71126322345834e-12	5	0	0	148	10287
R-HSA-8849473	PTK6 Expression	1.00000000000171	1.71126322345834e-12	5	0	0	148	10287
R-HSA-8875513	MET interacts with TNS proteins	1.00000000000171	1.71126322345834e-12	5	0	0	148	10287
R-HSA-1169092	Activation of RAS in B cells	1.00000000000171	1.71126322345834e-12	5	0	0	148	10287
R-HSA-8865999	MET activates PTPN11	1.00000000000171	1.71126322345834e-12	5	0	0	148	10287
R-HSA-112307	Transmission across Electrical Synapses	1.00000000000171	1.71126322345834e-12	5	0	0	148	10287
R-HSA-167826	The fatty acid cycling model	1.00000000000171	1.71126322345834e-12	5	0	0	148	10287
R-HSA-209931	Serotonin and melatonin biosynthesis	1.00000000000171	1.71126322345834e-12	5	0	0	148	10287
R-HSA-5661270	Catabolism of glucuronate to xylulose-5-phosphate	1.00000000000171	1.71126322345834e-12	5	0	0	148	10287
R-HSA-111469	SMAC-mediated apoptotic response	1.00000000000171	1.71126322345834e-12	5	0	0	148	10287
R-HSA-1483226	Synthesis of PI	1.00000000000171	1.71126322345834e-12	5	0	0	148	10287
R-HSA-3065676	SUMO is conjugated to E1 (UBA2:SAE1)	1.00000000000171	1.71126322345834e-12	5	0	0	148	10287
R-HSA-5662702	Melanin biosynthesis	1.00000000000171	1.71126322345834e-12	5	0	0	148	10287
R-HSA-5250913	Positive epigenetic regulation of rRNA expression	1.00000000000185	1.85347613054991e-12	108	0	0	148	10287
R-HSA-202403	TCR signaling	1.00000000000198	1.98318083943119e-12	119	0	0	148	10287
R-HSA-5693554	Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)	1.00000000000209	2.0907064225155e-12	27	0	0	148	10287
R-HSA-5654716	Downstream signaling of activated FGFR4	1.00000000000209	2.0907064225155e-12	27	0	0	148	10287
R-HSA-901042	Calnexin/calreticulin cycle	1.00000000000209	2.0907064225155e-12	27	0	0	148	10287
R-HSA-6783589	Interleukin-6 family signaling	1.00000000000209	2.0907064225155e-12	27	0	0	148	10287
R-HSA-1482788	Acyl chain remodelling of PC	1.00000000000209	2.0907064225155e-12	27	0	0	148	10287
R-HSA-2173788	Downregulation of TGF-beta receptor signaling	1.00000000000209	2.0907064225155e-12	27	0	0	148	10287
R-HSA-76066	RNA Polymerase III Transcription Initiation From Type 2 Promoter	1.00000000000209	2.0907064225155e-12	27	0	0	148	10287
R-HSA-69275	G2/M Transition	1.00000000000218	2.17739930310472e-12	182	0	0	148	10287
R-HSA-504046	RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription	1.00000000000219	2.1940101144255e-12	149	0	0	148	10287
R-HSA-168928	RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways	1.00000000000274	2.74259640178916e-12	84	0	0	148	10287
R-HSA-8852135	Protein ubiquitination	1.00000000000308	3.07959122596201e-12	62	0	0	148	10287
R-HSA-1268020	Mitochondrial protein import	1.00000000000308	3.07959122596201e-12	62	0	0	148	10287
R-HSA-72649	Translation initiation complex formation	1.00000000000308	3.07959122596201e-12	62	0	0	148	10287
R-HSA-6790901	rRNA modification in the nucleus and cytosol	1.00000000000308	3.07959122596201e-12	62	0	0	148	10287
R-HSA-5678895	Defective CFTR causes cystic fibrosis	1.00000000000308	3.07959122596201e-12	62	0	0	148	10287
R-HSA-72187	mRNA 3'-end processing	1.00000000000308	3.07959122596201e-12	62	0	0	148	10287
R-HSA-169911	Regulation of Apoptosis	1.00000000000322	3.2191278489662e-12	54	0	0	148	10287
R-HSA-69613	p53-Independent G1/S DNA damage checkpoint	1.00000000000322	3.2191278489662e-12	54	0	0	148	10287
R-HSA-69601	Ubiquitin Mediated Degradation of Phosphorylated Cdc25A	1.00000000000322	3.2191278489662e-12	54	0	0	148	10287
R-HSA-6781823	Formation of TC-NER Pre-Incision Complex	1.00000000000322	3.2191278489662e-12	54	0	0	148	10287
R-HSA-1592230	Mitochondrial biogenesis	1.00000000000322	3.2191278489662e-12	54	0	0	148	10287
R-HSA-69610	p53-Independent DNA Damage Response	1.00000000000322	3.2191278489662e-12	54	0	0	148	10287
R-HSA-429914	Deadenylation-dependent mRNA decay	1.00000000000325	3.25227288769007e-12	57	0	0	148	10287
R-HSA-450408	AUF1 (hnRNP D0) binds and destabilizes mRNA	1.00000000000325	3.25227288769007e-12	57	0	0	148	10287
R-HSA-3000178	ECM proteoglycans	1.00000000000325	3.25227288769007e-12	57	0	0	148	10287
R-HSA-432722	Golgi Associated Vesicle Biogenesis	1.00000000000325	3.25227288769007e-12	57	0	0	148	10287
R-HSA-5619115	Disorders of transmembrane transporters	1.00000000000335	3.35146585843714e-12	76	0	0	148	10287
R-HSA-1169410	Antiviral mechanism by IFN-stimulated genes	1.00000000000335	3.35146585843714e-12	76	0	0	148	10287
R-HSA-427389	ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression	1.00000000000335	3.35146585843714e-12	76	0	0	148	10287
R-HSA-5693606	DNA Double Strand Break Response	1.00000000000335	3.35146585843714e-12	76	0	0	148	10287
R-HSA-176409	APC/C:Cdc20 mediated degradation of mitotic proteins	1.00000000000335	3.35146585843714e-12	76	0	0	148	10287
R-HSA-1169408	ISG15 antiviral mechanism	1.00000000000335	3.35146585843714e-12	76	0	0	148	10287
R-HSA-5423646	Aflatoxin activation and detoxification	1.0000000000038	3.79930905382942e-12	21	0	0	148	10287
R-HSA-2024096	HS-GAG degradation	1.0000000000038	3.79930905382942e-12	21	0	0	148	10287
R-HSA-3000480	Scavenging by Class A Receptors	1.0000000000038	3.79930905382942e-12	21	0	0	148	10287
R-HSA-2022870	Chondroitin sulfate biosynthesis	1.0000000000038	3.79930905382942e-12	21	0	0	148	10287
R-HSA-69618	Mitotic Spindle Checkpoint	1.0000000000038	3.79930905382942e-12	21	0	0	148	10287
R-HSA-500657	Presynaptic function of Kainate receptors	1.0000000000038	3.79930905382942e-12	21	0	0	148	10287
R-HSA-5654688	SHC-mediated cascade:FGFR1	1.0000000000038	3.79930905382942e-12	21	0	0	148	10287
R-HSA-5651801	PCNA-Dependent Long Patch Base Excision Repair	1.0000000000038	3.79930905382942e-12	21	0	0	148	10287
R-HSA-2979096	NOTCH2 Activation and Transmission of Signal to the Nucleus	1.0000000000038	3.79930905382942e-12	21	0	0	148	10287
R-HSA-5654689	PI-3K cascade:FGFR1	1.0000000000038	3.79930905382942e-12	21	0	0	148	10287
R-HSA-6807004	Negative regulation of MET activity	1.0000000000038	3.79930905382942e-12	21	0	0	148	10287
R-HSA-8849932	SALM protein interactions at the synapses	1.0000000000038	3.79930905382942e-12	21	0	0	148	10287
R-HSA-1810476	RIP-mediated NFkB activation via ZBP1	1.0000000000038	3.79930905382942e-12	21	0	0	148	10287
R-HSA-210745	Regulation of gene expression in beta cells	1.0000000000038	3.79930905382942e-12	21	0	0	148	10287
R-HSA-381426	Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)	1.0000000000038	3.79930905382942e-12	21	0	0	148	10287
R-HSA-445144	Signal transduction by L1	1.0000000000038	3.79930905382942e-12	21	0	0	148	10287
R-HSA-196741	Cobalamin (Cbl, vitamin B12) transport and metabolism	1.0000000000038	3.79930905382942e-12	21	0	0	148	10287
R-HSA-2033519	Activated point mutants of FGFR2	1.00000000000467	4.6653564980595e-12	17	0	0	148	10287
R-HSA-1482922	Acyl chain remodelling of PI	1.00000000000467	4.6653564980595e-12	17	0	0	148	10287
R-HSA-937072	TRAF6 mediated induction of TAK1 complex	1.00000000000467	4.6653564980595e-12	17	0	0	148	10287
R-HSA-5656121	Translesion synthesis by POLI	1.00000000000467	4.6653564980595e-12	17	0	0	148	10287
R-HSA-193639	p75NTR signals via NF-kB	1.00000000000467	4.6653564980595e-12	17	0	0	148	10287
R-HSA-5655862	Translesion synthesis by POLK	1.00000000000467	4.6653564980595e-12	17	0	0	148	10287
R-HSA-5083632	Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)	1.00000000000467	4.6653564980595e-12	17	0	0	148	10287
R-HSA-156711	Polo-like kinase mediated events	1.00000000000467	4.6653564980595e-12	17	0	0	148	10287
R-HSA-442729	CREB phosphorylation through the activation of CaMKII	1.00000000000467	4.6653564980595e-12	17	0	0	148	10287
R-HSA-438066	Unblocking of NMDA receptor, glutamate binding and activation	1.00000000000467	4.6653564980595e-12	17	0	0	148	10287
R-HSA-622312	Inflammasomes	1.00000000000467	4.6653564980595e-12	17	0	0	148	10287
R-HSA-199220	Vitamin B5 (pantothenate) metabolism	1.00000000000467	4.6653564980595e-12	17	0	0	148	10287
R-HSA-140534	Ligand-dependent caspase activation	1.00000000000467	4.6653564980595e-12	17	0	0	148	10287
R-HSA-5627117	RHO GTPases Activate ROCKs	1.00000000000467	4.6653564980595e-12	17	0	0	148	10287
R-HSA-5083636	Defective GALNT12 causes colorectal cancer 1 (CRCS1)	1.00000000000467	4.6653564980595e-12	17	0	0	148	10287
R-HSA-5625900	RHO GTPases activate CIT	1.00000000000467	4.6653564980595e-12	17	0	0	148	10287
R-HSA-196299	Beta-catenin phosphorylation cascade	1.00000000000467	4.6653564980595e-12	17	0	0	148	10287
R-HSA-429958	mRNA decay by 3' to 5' exoribonuclease	1.00000000000467	4.6653564980595e-12	17	0	0	148	10287
R-HSA-2142845	Hyaluronan metabolism	1.00000000000467	4.6653564980595e-12	17	0	0	148	10287
R-HSA-192456	Digestion of dietary lipid	1.00000000000467	4.6653564980595e-12	17	0	0	148	10287
R-HSA-5083625	Defective GALNT3 causes familial hyperphosphatemic tumoral calcinosis (HFTC)	1.00000000000467	4.6653564980595e-12	17	0	0	148	10287
R-HSA-3232118	SUMOylation of transcription factors	1.00000000000467	4.6653564980595e-12	17	0	0	148	10287
R-HSA-2173791	TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)	1.00000000000467	4.6653564980595e-12	17	0	0	148	10287
R-HSA-3296482	Defects in vitamin and cofactor metabolism	1.00000000000467	4.6653564980595e-12	17	0	0	148	10287
R-HSA-70221	Glycogen breakdown (glycogenolysis)	1.00000000000467	4.6653564980595e-12	17	0	0	148	10287
R-HSA-392518	Signal amplification	1.00000000000512	5.12391024669761e-12	33	0	0	148	10287
R-HSA-202433	Generation of second messenger molecules	1.00000000000512	5.12391024669761e-12	33	0	0	148	10287
R-HSA-1638074	Keratan sulfate/keratin metabolism	1.00000000000512	5.12391024669761e-12	33	0	0	148	10287
R-HSA-1980145	Signaling by NOTCH2	1.00000000000512	5.12391024669761e-12	33	0	0	148	10287
R-HSA-186712	Regulation of beta-cell development	1.00000000000512	5.12391024669761e-12	33	0	0	148	10287
R-HSA-4085001	Sialic acid metabolism	1.00000000000512	5.12391024669761e-12	33	0	0	148	10287
R-HSA-5357905	Regulation of TNFR1 signaling	1.00000000000512	5.12391024669761e-12	33	0	0	148	10287
R-HSA-5654726	Negative regulation of FGFR1 signaling	1.00000000000512	5.12391024669761e-12	33	0	0	148	10287
R-HSA-180746	Nuclear import of Rev protein	1.00000000000512	5.12391024669761e-12	33	0	0	148	10287
R-HSA-180910	Vpr-mediated nuclear import of PICs	1.00000000000512	5.12391024669761e-12	33	0	0	148	10287
R-HSA-6783783	Interleukin-10 signaling	1.00000000000552	5.52152693722412e-12	49	0	0	148	10287
R-HSA-6811440	Retrograde transport at the Trans-Golgi-Network	1.00000000000552	5.52152693722412e-12	49	0	0	148	10287
R-HSA-72766	Translation	1.00000000000582	5.82402487640051e-12	162	0	0	148	10287
R-HSA-5637815	Signaling by Ligand-Responsive EGFR Variants in Cancer	1.00000000000655	6.55164445713161e-12	20	0	0	148	10287
R-HSA-8874081	MET activates PTK2 signaling	1.00000000000655	6.55164445713161e-12	20	0	0	148	10287
R-HSA-6804760	Regulation of TP53 Activity through Methylation	1.00000000000655	6.55164445713161e-12	20	0	0	148	10287
R-HSA-5654720	PI-3K cascade:FGFR4	1.00000000000655	6.55164445713161e-12	20	0	0	148	10287
R-HSA-141430	Inactivation of APC/C via direct inhibition of the APC/C complex	1.00000000000655	6.55164445713161e-12	20	0	0	148	10287
R-HSA-5654719	SHC-mediated cascade:FGFR4	1.00000000000655	6.55164445713161e-12	20	0	0	148	10287
R-HSA-194223	HDL-mediated lipid transport	1.00000000000655	6.55164445713161e-12	20	0	0	148	10287
R-HSA-190241	FGFR2 ligand binding and activation	1.00000000000655	6.55164445713161e-12	20	0	0	148	10287
R-HSA-5654706	FRS-mediated FGFR3 signaling	1.00000000000655	6.55164445713161e-12	20	0	0	148	10287
R-HSA-69186	Lagging Strand Synthesis	1.00000000000655	6.55164445713161e-12	20	0	0	148	10287
R-HSA-1236382	Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants	1.00000000000655	6.55164445713161e-12	20	0	0	148	10287
R-HSA-141405	Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components	1.00000000000655	6.55164445713161e-12	20	0	0	148	10287
R-HSA-8876384	Listeria monocytogenes entry into host cells	1.00000000000655	6.55164445713161e-12	20	0	0	148	10287
R-HSA-163560	Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis	1.00000000000655	6.55164445713161e-12	20	0	0	148	10287
R-HSA-381771	Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)	1.00000000000655	6.55164445713161e-12	20	0	0	148	10287
R-HSA-1643713	Signaling by EGFR in Cancer	1.00000000000655	6.55164445713161e-12	20	0	0	148	10287
R-HSA-418217	G beta:gamma signalling through PLC beta	1.00000000000655	6.55164445713161e-12	20	0	0	148	10287
R-HSA-6788467	IL-6-type cytokine receptor ligand interactions	1.00000000000655	6.55164445713161e-12	20	0	0	148	10287
R-HSA-212165	Epigenetic regulation of gene expression	1.00000000000679	6.78806363769502e-12	151	0	0	148	10287
R-HSA-2467813	Separation of Sister Chromatids	1.00000000000702	7.01766989941958e-12	168	0	0	148	10287
R-HSA-69580	p53-Dependent G1/S DNA damage checkpoint	1.0000000000071	7.10448563366605e-12	65	0	0	148	10287
R-HSA-913709	O-linked glycosylation of mucins	1.0000000000071	7.10448563366605e-12	65	0	0	148	10287
R-HSA-2219530	Constitutive Signaling by Aberrant PI3K in Cancer	1.0000000000071	7.10448563366605e-12	65	0	0	148	10287
R-HSA-5334118	DNA methylation	1.0000000000071	7.10448563366605e-12	65	0	0	148	10287
R-HSA-6782210	Gap-filling DNA repair synthesis and ligation in TC-NER	1.0000000000071	7.10448563366605e-12	65	0	0	148	10287
R-HSA-69563	p53-Dependent G1 DNA Damage Response	1.0000000000071	7.10448563366605e-12	65	0	0	148	10287
R-HSA-6782135	Dual incision in TC-NER	1.00000000000733	7.32952802195344e-12	66	0	0	148	10287
R-HSA-156827	L13a-mediated translational silencing of Ceruloplasmin expression	1.00000000000739	7.3947609874524e-12	117	0	0	148	10287
R-HSA-72706	GTP hydrolysis and joining of the 60S ribosomal subunit	1.00000000000739	7.3947609874524e-12	117	0	0	148	10287
R-HSA-69239	Synthesis of DNA	1.00000000000756	7.56421166126959e-12	101	0	0	148	10287
R-HSA-1655829	Regulation of cholesterol biosynthesis by SREBP (SREBF)	1.0000000000086	8.60223173871596e-12	55	0	0	148	10287
R-HSA-180585	Vif-mediated degradation of APOBEC3G	1.0000000000086	8.60223173871596e-12	55	0	0	148	10287
R-HSA-453274	Mitotic G2-G2/M phases	1.00000000000983	9.83335496693665e-12	184	0	0	148	10287
R-HSA-3214847	HATs acetylate histones	1.00000000001017	1.01655274465163e-11	143	0	0	148	10287
R-HSA-68877	Mitotic Prometaphase	1.00000000001127	1.12729429375014e-11	111	0	0	148	10287
R-HSA-76009	Platelet Aggregation (Plug Formation)	1.00000000001138	1.13826901855277e-11	38	0	0	148	10287
R-HSA-5689901	Metalloprotease DUBs	1.00000000001138	1.13826901855277e-11	38	0	0	148	10287
R-HSA-5655302	Signaling by FGFR1 in disease	1.00000000001138	1.13826901855277e-11	38	0	0	148	10287
R-HSA-156590	Glutathione conjugation	1.00000000001138	1.13826901855277e-11	38	0	0	148	10287
R-HSA-5685938	HDR through Single Strand Annealing (SSA)	1.00000000001138	1.13826901855277e-11	38	0	0	148	10287
R-HSA-72737	Cap-dependent Translation Initiation	1.00000000001206	1.20568261018913e-11	125	0	0	148	10287
R-HSA-72613	Eukaryotic Translation Initiation	1.00000000001206	1.20568261018913e-11	125	0	0	148	10287
R-HSA-2555396	Mitotic Metaphase and Anaphase	1.00000000001255	1.25464294993772e-11	180	0	0	148	10287
R-HSA-1834949	Cytosolic sensors of pathogen-associated DNA	1.00000000001543	1.54290504212074e-11	68	0	0	148	10287
R-HSA-174154	APC/C:Cdc20 mediated degradation of Securin	1.00000000001543	1.54290504212074e-11	68	0	0	148	10287
R-HSA-1169091	Activation of NF-kappaB in B cells	1.00000000001543	1.54290504212074e-11	68	0	0	148	10287
R-HSA-2559586	DNA Damage/Telomere Stress Induced Senescence	1.00000000001823	1.8225875024373e-11	79	0	0	148	10287
R-HSA-2871837	FCERI mediated NF-kB activation	1.00000000001823	1.8225875024373e-11	79	0	0	148	10287
R-HSA-6781827	Transcription-Coupled Nucleotide Excision Repair (TC-NER)	1.00000000001823	1.8225875024373e-11	79	0	0	148	10287
R-HSA-3214858	RMTs methylate histone arginines	1.00000000001823	1.8225875024373e-11	79	0	0	148	10287
R-HSA-6791226	Major pathway of rRNA processing in the nucleolus and cytosol	1.00000000001921	1.92149552012398e-11	179	0	0	148	10287
R-HSA-68882	Mitotic Anaphase	1.00000000001921	1.92149552012398e-11	179	0	0	148	10287