TermID Term Enrichment logP Genes in Term Target Genes in Term Fraction of Targets in Term Total Target Genes Total Genes Entrez Gene IDs Gene Symbols HUMAN_PWY66-5 superpathway of cholesterol biosynthesis 0.000218940547772174 -8.42671033636273 25 10 0.0952380952380952 105 902 1595,3157,3422,4598,6307,4597,1718,6713,1717,3156 CYP51A1,HMGCS1,IDI1,MVK,MSMO1,MVD,DHCR24,SQLE,DHCR7,HMGCR META_PWY66-5 superpathway of cholesterol biosynthesis 0.00056554256125041 -7.47772500219794 23 9 0.0857142857142857 105 902 1595,3157,3422,4598,6307,4597,6713,1717,3156 CYP51A1,HMGCS1,IDI1,MVK,MSMO1,MVD,SQLE,DHCR7,HMGCR META_PWY-922 mevalonate pathway I 0.00304340177047752 -5.79477938573514 10 5 0.0476190476190476 105 902 3157,3422,4598,4597,3156 HMGCS1,IDI1,MVK,MVD,HMGCR HUMAN_PWY-922 mevalonate pathway 0.00304340177047752 -5.79477938573514 10 5 0.0476190476190476 105 902 3157,3422,4598,4597,3156 HMGCS1,IDI1,MVK,MVD,HMGCR HUMAN_PWY-5910 superpathway of geranylgeranyldiphosphate biosynthesis I (via mevalonate) 0.00788944871709767 -4.84222901765574 12 5 0.0476190476190476 105 902 3157,3422,4598,4597,3156 HMGCS1,IDI1,MVK,MVD,HMGCR META_PWY-5910 superpathway of geranylgeranyldiphosphate biosynthesis I (via mevalonate) 0.00788944871709767 -4.84222901765574 12 5 0.0476190476190476 105 902 3157,3422,4598,4597,3156 HMGCS1,IDI1,MVK,MVD,HMGCR HUMAN_PWY66-4 cholesterol biosynthesis III (via desmosterol) 0.0116477593645568 -4.45264144669066 13 5 0.0476190476190476 105 902 6713,1595,1717,6307,1718 SQLE,CYP51A1,DHCR7,MSMO1,DHCR24 HUMAN_PWY66-341 cholesterol biosynthesis I 0.0116477593645568 -4.45264144669066 13 5 0.0476190476190476 105 902 6713,1595,1717,6307,1718 SQLE,CYP51A1,DHCR7,MSMO1,DHCR24 HUMAN_PWY66-3 cholesterol biosynthesis II (via 24,25-dihydrolanosterol) 0.0116477593645568 -4.45264144669066 13 5 0.0476190476190476 105 902 6713,1595,1717,6307,1718 SQLE,CYP51A1,DHCR7,MSMO1,DHCR24 META_NADSYN-PWY NAD biosynthesis II (from tryptophan) 0.0137651507952143 -4.28561518547378 9 4 0.0380952380952381 105 902 349565,6999,8564,23475 NMNAT3,TDO2,KMO,QPRT META_PWY-6571 dermatan sulfate biosynthesis 0.022451413621951 -3.79640169920605 15 5 0.0476190476190476 105 902 337876,10090,22856,11285,64131 CHSY3,UST,CHSY1,B4GALT7,XYLT1 HUMAN_PWY66-401 superpathway of tryptophan utilization 0.0248257134435439 -3.6958753305497 32 8 0.0761904761904762 105 902 349565,217,6999,8564,4128,113612,23475,1545 NMNAT3,ALDH2,TDO2,KMO,MAOA,CYP2U1,QPRT,CYP1B1 META_PWY66-341 cholesterol biosynthesis I 0.0299679733124821 -3.50762602381463 11 4 0.0380952380952381 105 902 6713,1595,1717,6307 SQLE,CYP51A1,DHCR7,MSMO1 META_PWY66-4 cholesterol biosynthesis III (via desmosterol) 0.0299679733124821 -3.50762602381463 11 4 0.0380952380952381 105 902 6713,1595,1717,6307 SQLE,CYP51A1,DHCR7,MSMO1 META_PWY66-3 cholesterol biosynthesis II (via 24,25-dihydrolanosterol) 0.0299679733124821 -3.50762602381463 11 4 0.0380952380952381 105 902 6713,1595,1717,6307 SQLE,CYP51A1,DHCR7,MSMO1 HUMAN_NADSYN-PWY NAD de novo biosynthesis 0.0299679733124821 -3.50762602381463 11 4 0.0380952380952381 105 902 349565,6999,8564,23475 NMNAT3,TDO2,KMO,QPRT META_PWY-6000 gamma-linolenate biosynthesis II (animals) 0.0372344762696309 -3.2905201654581 3 2 0.019047619047619 105 902 2180,11001 ACSL1,SLC27A2 HUMAN_PWY-4202 arsenate detoxification I (glutaredoxin) 0.0372344762696309 -3.2905201654581 3 2 0.019047619047619 105 902 9446,4860 GSTO1,PNP META_PWY-4202 arsenate detoxification I (glutaredoxin) 0.0372344762696309 -3.2905201654581 3 2 0.019047619047619 105 902 9446,4860 GSTO1,PNP META_PWY-6569 chondroitin sulfate biosynthesis 0.0481957911762038 -3.03248358173397 18 5 0.0476190476190476 105 902 337876,10090,22856,11285,64131 CHSY3,UST,CHSY1,B4GALT7,XYLT1 HUMAN_PWY-6564 heparan sulfate biosynthesis 0.0601349634773959 -2.81116385156329 25 6 0.0571428571428571 105 902 9953,11285,64131,266722,26035,222537 HS3ST3B1,B4GALT7,XYLT1,HS6ST3,GLCE,HS3ST5 HUMAN_PWY-7433 mucin core 1 and core 2 O-glycosylation 0.0601349634773959 -2.81116385156329 25 6 0.0571428571428571 105 902 2591,2589,114805,374378,11226,79695 GALNT3,GALNT1,GALNT13,GALNT18,GALNT6,GALNT12 META_PWY66-423 fructose 2,6-bisphosphate biosynthesis 0.0688413653639685 -2.67595047396029 4 2 0.019047619047619 105 902 5210,5208 PFKFB4,PFKFB2 META_PWY-7434 terminal O-glycans residues modification 0.0688413653639685 -2.67595047396029 4 2 0.019047619047619 105 902 2651,10690 GCNT2,FUT9 META_PWY66-373 sucrose degradation V (sucrose alpha-glucosidase) 0.0688413653639685 -2.67595047396029 4 2 0.019047619047619 105 902 230,226 ALDOC,ALDOA META_PWY-6313 serotonin degradation 0.0688413653639685 -2.67595047396029 4 2 0.019047619047619 105 902 4128,217 MAOA,ALDH2 META_PWY-7592 arachidonate biosynthesis III (6-desaturase, mammals) 0.0688413653639685 -2.67595047396029 4 2 0.019047619047619 105 902 2180,11001 ACSL1,SLC27A2 META_PWY-5653 NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde 0.0688413653639685 -2.67595047396029 4 2 0.019047619047619 105 902 349565,23475 NMNAT3,QPRT HUMAN_PWY66-423 fructose 2,6-bisphosphate synthesis 0.0688413653639685 -2.67595047396029 4 2 0.019047619047619 105 902 5210,5208 PFKFB4,PFKFB2 HUMAN_PWY-5653 NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde 0.0688413653639685 -2.67595047396029 4 2 0.019047619047619 105 902 349565,23475 NMNAT3,QPRT META_ANAEROFRUCAT-PWY homolactic fermentation 0.0860521258837884 -2.45280205141432 15 4 0.0380952380952381 105 902 3098,2026,230,226 HK1,ENO2,ALDOC,ALDOA HUMAN_PWY66-400 glycolysis 0.0860521258837884 -2.45280205141432 15 4 0.0380952380952381 105 902 3098,2026,230,226 HK1,ENO2,ALDOC,ALDOA META_ANAGLYCOLYSIS-PWY glycolysis III (from glucose) 0.0860521258837884 -2.45280205141432 15 4 0.0380952380952381 105 902 3098,2026,230,226 HK1,ENO2,ALDOC,ALDOA HUMAN_PWY-4983 citrulline-nitric oxide cycle 0.106150165408206 -2.24290053258438 5 2 0.019047619047619 105 902 445,4846 ASS1,NOS3 META_PWY-6566 chondroitin biosynthesis 0.106150165408206 -2.24290053258438 5 2 0.019047619047619 105 902 337876,22856 CHSY3,CHSY1 HUMAN_COA-PWY-1 coenzyme A biosynthesis 0.106150165408206 -2.24290053258438 5 2 0.019047619047619 105 902 79646,53354 PANK3,PANK1 META_PWY-6074 zymosterol biosynthesis 0.106150165408206 -2.24290053258438 5 2 0.019047619047619 105 902 1595,6307 CYP51A1,MSMO1 META_PWY-4983 L-citrulline-nitric oxide cycle 0.106150165408206 -2.24290053258438 5 2 0.019047619047619 105 902 445,4846 ASS1,NOS3 META_PWY-5651 L-tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde 0.106150165408206 -2.24290053258438 5 2 0.019047619047619 105 902 6999,8564 TDO2,KMO META_COA-PWY-1 coenzyme A biosynthesis II (mammalian) 0.106150165408206 -2.24290053258438 5 2 0.019047619047619 105 902 79646,53354 PANK3,PANK1 META_PWY-6292 superpathway of L-cysteine biosynthesis (mammalian) 0.116407982261737 -2.15065416990427 1 1 0.00952380952380952 105 902 875 CBS HUMAN_PWY-6399 melatonin degradation II 0.116407982261737 -2.15065416990427 1 1 0.00952380952380952 105 902 4128 MAOA META_PWY-5966 fatty acid biosynthesis initiation II 0.116407982261737 -2.15065416990427 1 1 0.00952380952380952 105 902 2194 FASN HUMAN_PWY-6898 thiamin salvage III 0.116407982261737 -2.15065416990427 1 1 0.00952380952380952 105 902 27010 TPK1 HUMAN_HOMOCYSDEGR-PWY cysteine biosynthesis/homocysteine degradation (trans-sulfuration) 0.116407982261737 -2.15065416990427 1 1 0.00952380952380952 105 902 875 CBS HUMAN_PWY66-426 hydrogen sulfide biosynthesis (trans-sulfuration) 0.116407982261737 -2.15065416990427 1 1 0.00952380952380952 105 902 875 CBS HUMAN_PWY-6535 4-aminobutyrate degradation 0.116407982261737 -2.15065416990427 1 1 0.00952380952380952 105 902 18 ABAT META_MGLDLCTANA-PWY methylglyoxal degradation VI 0.116407982261737 -2.15065416990427 1 1 0.00952380952380952 105 902 197257 LDHD HUMAN_PWY-5963 thio-molybdenum cofactor biosynthesis 0.116407982261737 -2.15065416990427 1 1 0.00952380952380952 105 902 55034 MOCOS META_PWY-7435 mucin core 3 and core 4 O-glycosylation 0.116407982261737 -2.15065416990427 1 1 0.00952380952380952 105 902 2589 GALNT1 META_PWY-6535 4-aminobutanoate degradation I 0.116407982261737 -2.15065416990427 1 1 0.00952380952380952 105 902 18 ABAT HUMAN_MGLDLCTANA-PWY methylglyoxal degradation VI 0.116407982261737 -2.15065416990427 1 1 0.00952380952380952 105 902 197257 LDHD META_PWY-6564 heparan sulfate biosynthesis 0.118532433016114 -2.13256865951644 23 5 0.0476190476190476 105 902 9953,11285,64131,266722,26035 HS3ST3B1,B4GALT7,XYLT1,HS6ST3,GLCE HUMAN_PWY-6402 superpathway of melatonin degradation 0.126399176324544 -2.06831031371036 11 3 0.0285714285714286 105 902 4128,113612,1545 MAOA,CYP2U1,CYP1B1 META_PWY-5972 stearate biosynthesis I (animals and fungi) 0.147431084074557 -1.9143944389998 6 2 0.019047619047619 105 902 2180,11001 ACSL1,SLC27A2 HUMAN_PWY-5143 fatty acid activation 0.147431084074557 -1.9143944389998 6 2 0.019047619047619 105 902 2180,11001 ACSL1,SLC27A2 HUMAN_PWY-6557 glycoaminoglycan-protein linkage region biosynthesis 0.147431084074557 -1.9143944389998 6 2 0.019047619047619 105 902 11285,64131 B4GALT7,XYLT1 HUMAN_PWY-6074 zymosterol biosynthesis 0.147431084074557 -1.9143944389998 6 2 0.019047619047619 105 902 1595,6307 CYP51A1,MSMO1 HUMAN_PWY66-373 sucrose degradation 0.147431084074557 -1.9143944389998 6 2 0.019047619047619 105 902 230,226 ALDOC,ALDOA HUMAN_PWY-6313 serotonin degradation 0.147431084074557 -1.9143944389998 6 2 0.019047619047619 105 902 4128,217 MAOA,ALDH2 META_PWY-6557 glycoaminoglycan-protein linkage region biosynthesis 0.147431084074557 -1.9143944389998 6 2 0.019047619047619 105 902 11285,64131 B4GALT7,XYLT1 META_PWY66-391 fatty acid beta-oxidation VI (peroxisome) 0.154863156562858 -1.86521341289888 12 3 0.0285714285714286 105 902 2180,1962,11001 ACSL1,EHHADH,SLC27A2 HUMAN_PWY-6571 dermatan sulfate biosynthesis 0.154863156562858 -1.86521341289888 12 3 0.0285714285714286 105 902 10090,11285,64131 UST,B4GALT7,XYLT1 HUMAN_PWY-6000 gamma-linolenate biosynthesis 0.154863156562858 -1.86521341289888 12 3 0.0285714285714286 105 902 2180,11001,6296 ACSL1,SLC27A2,ACSM3 HUMAN_TRIGLSYN-PWY triacylglycerol biosynthesis 0.155569562205719 -1.86066230201756 25 5 0.0476190476190476 105 902 8611,129642,64748,56895,8612 PLPP1,MBOAT2,PLPPR2,AGPAT4,PLPP2 HUMAN_PWY-6558 heparan sulfate biosynthesis (late stages) 0.170783471968249 -1.7673587706458 19 4 0.0380952380952381 105 902 9953,266722,26035,222537 HS3ST3B1,HS6ST3,GLCE,HS3ST5 HUMAN_PWY66-391 fatty acid beta-oxidation (peroxisome) 0.185105336016215 -1.68683023206987 13 3 0.0285714285714286 105 902 2180,1962,11001 ACSL1,EHHADH,SLC27A2 HUMAN_PWY-6363 D-myo-inositol (1,4,5)-trisphosphate degradation 0.185105336016215 -1.68683023206987 13 3 0.0285714285714286 105 902 22876,3636,3628 INPP5F,INPPL1,INPP1 HUMAN_PWY-5651 tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde 0.191273631176322 -1.65405025220235 7 2 0.019047619047619 105 902 6999,8564 TDO2,KMO META_FAO-PWY fatty acid beta-oxidation I 0.216745354217166 -1.52903209738203 14 3 0.0285714285714286 105 902 2180,1962,11001 ACSL1,EHHADH,SLC27A2 META_PWY-6620 guanine and guanosine salvage 0.219379305080205 -1.51695306065733 2 1 0.00952380952380952 105 902 4860 PNP HUMAN_PWY-6129 dolichol and dolichyl phosphate biosynthesis 0.219379305080205 -1.51695306065733 2 1 0.00952380952380952 105 902 79644 SRD5A3 HUMAN_PWY-7179-1 purine deoxyribonucleosides degradation 0.219379305080205 -1.51695306065733 2 1 0.00952380952380952 105 902 4860 PNP META_PWY6666-2 dopamine degradation 0.219379305080205 -1.51695306065733 2 1 0.00952380952380952 105 902 4128 MAOA HUMAN_PROSYN-PWY proline biosynthesis 0.219379305080205 -1.51695306065733 2 1 0.00952380952380952 105 902 5831 PYCR1 HUMAN_BETA-ALA-DEGRADATION-I-PWY beta-alanine degradation 0.219379305080205 -1.51695306065733 2 1 0.00952380952380952 105 902 18 ABAT HUMAN_PWY-4821 UDP-D-xylose and UDP-D-glucuronate biosynthesis 0.219379305080205 -1.51695306065733 2 1 0.00952380952380952 105 902 7358 UGDH HUMAN_PWY6666-1 anandamide degradation 0.219379305080205 -1.51695306065733 2 1 0.00952380952380952 105 902 158584 FAAH2 META_PWY3O-4106 NAD salvage pathway III 0.219379305080205 -1.51695306065733 2 1 0.00952380952380952 105 902 349565 NMNAT3 HUMAN_PWY-6620 guanine and guanosine salvage 0.219379305080205 -1.51695306065733 2 1 0.00952380952380952 105 902 4860 PNP HUMAN_PWY-6370 ascorbate recycling (cytosolic) 0.219379305080205 -1.51695306065733 2 1 0.00952380952380952 105 902 9446 GSTO1 HUMAN_PWY-5525 D-glucuronate degradation 0.219379305080205 -1.51695306065733 2 1 0.00952380952380952 105 902 51084 CRYL1 META_PWY-0 putrescine degradation III 0.219379305080205 -1.51695306065733 2 1 0.00952380952380952 105 902 217 ALDH2 HUMAN_PWY-5386 methylglyoxal degradation I 0.219379305080205 -1.51695306065733 2 1 0.00952380952380952 105 902 197257 LDHD HUMAN_FASYN-ELONG-PWY fatty acid elongation -- saturated 0.219379305080205 -1.51695306065733 2 1 0.00952380952380952 105 902 2194 FASN HUMAN_PWY-4041 gamma-glutamyl cycle 0.219379305080205 -1.51695306065733 2 1 0.00952380952380952 105 902 26873 OPLAH META_LYSINE-DEG1-PWY L-lysine degradation XI (mammalian) 0.219379305080205 -1.51695306065733 2 1 0.00952380952380952 105 902 10157 AASS HUMAN_PWY-5670 epoxysqualene biosynthesis 0.219379305080205 -1.51695306065733 2 1 0.00952380952380952 105 902 6713 SQLE META_PROSYN-PWY L-proline biosynthesis I 0.219379305080205 -1.51695306065733 2 1 0.00952380952380952 105 902 5831 PYCR1 HUMAN_LYSINE-DEG1-PWY lysine degradation I (saccharopine pathway) 0.219379305080205 -1.51695306065733 2 1 0.00952380952380952 105 902 10157 AASS META_GLUDEG-I-PWY GABA shunt 0.219379305080205 -1.51695306065733 2 1 0.00952380952380952 105 902 18 ABAT META_PWY-5670 epoxysqualene biosynthesis 0.219379305080205 -1.51695306065733 2 1 0.00952380952380952 105 902 6713 SQLE META_PWY-7179-1 purine deoxyribonucleosides degradation II 0.219379305080205 -1.51695306065733 2 1 0.00952380952380952 105 902 4860 PNP HUMAN_PWY-1801 formaldehyde oxidation 0.219379305080205 -1.51695306065733 2 1 0.00952380952380952 105 902 2098 ESD HUMAN_PWY-5137 fatty acid beta-oxidation (unsaturated, odd number) 0.219379305080205 -1.51695306065733 2 1 0.00952380952380952 105 902 1962 EHHADH HUMAN_ASPARAGINE-BIOSYNTHESIS asparagine biosynthesis 0.219379305080205 -1.51695306065733 2 1 0.00952380952380952 105 902 440 ASNS META_PWY-6370 ascorbate recycling (cytosolic) 0.219379305080205 -1.51695306065733 2 1 0.00952380952380952 105 902 9446 GSTO1 HUMAN_TRYPTOPHAN-DEGRADATION-1 tryptophan degradation 0.236536774776311 -1.44165158725546 8 2 0.019047619047619 105 902 6999,8564 TDO2,KMO META_PWY-7426 mannosyl-glycoprotein N-acetylglucosaminyltransferases 0.236536774776311 -1.44165158725546 8 2 0.019047619047619 105 902 4245,11282 MGAT1,MGAT4B HUMAN_PWY-0 putrescine degradation III 0.236536774776311 -1.44165158725546 8 2 0.019047619047619 105 902 4128,217 MAOA,ALDH2 META_TRYPTOPHAN-DEGRADATION-1 L-tryptophan degradation III (eukaryotic) 0.236536774776311 -1.44165158725546 8 2 0.019047619047619 105 902 6999,8564 TDO2,KMO HUMAN_PWY-7434 terminal O-glycans residues modification 0.236536774776311 -1.44165158725546 8 2 0.019047619047619 105 902 2651,10690 GCNT2,FUT9 HUMAN_PWY-2201 folate transformations I 0.236536774776311 -1.44165158725546 8 2 0.019047619047619 105 902 160428,10840 ALDH1L2,ALDH1L1 HUMAN_PWY66-399 gluconeogenesis 0.249418661300664 -1.3886224237533 15 3 0.0285714285714286 105 902 2026,230,226 ENO2,ALDOC,ALDOA META_PWY66-399 gluconeogenesis III 0.249418661300664 -1.3886224237533 15 3 0.0285714285714286 105 902 2026,230,226 ENO2,ALDOC,ALDOA HUMAN_PWY-6342 noradrenaline and adrenaline degradation 0.282306217521793 -1.26476291944595 9 2 0.019047619047619 105 902 4128,217 MAOA,ALDH2 META_PWY-6309 L-tryptophan degradation XI (mammalian, via kynurenine) 0.282306217521793 -1.26476291944595 9 2 0.019047619047619 105 902 6999,8564 TDO2,KMO HUMAN_PWY-6569 chondroitin sulfate biosynthesis 0.282783347009366 -1.26307423279907 16 3 0.0285714285714286 105 902 10090,11285,64131 UST,B4GALT7,XYLT1 HUMAN_PWY6666-2 dopamine degradation 0.310451719489736 -1.16972688248554 3 1 0.00952380952380952 105 902 4128 MAOA META_PWY-6609 adenine and adenosine salvage III 0.310451719489736 -1.16972688248554 3 1 0.00952380952380952 105 902 4860 PNP HUMAN_2PHENDEG-PWY phenylethylamine degradation I 0.310451719489736 -1.16972688248554 3 1 0.00952380952380952 105 902 217 ALDH2 META_GLYCLEAV-PWY glycine cleavage 0.310451719489736 -1.16972688248554 3 1 0.00952380952380952 105 902 2731 GLDC META_PWY66-21 ethanol degradation II 0.310451719489736 -1.16972688248554 3 1 0.00952380952380952 105 902 217 ALDH2 META_PWY0-1296 purine ribonucleosides degradation 0.310451719489736 -1.16972688248554 3 1 0.00952380952380952 105 902 4860 PNP HUMAN_NAD-BIOSYNTHESIS-III NAD salvage 0.310451719489736 -1.16972688248554 3 1 0.00952380952380952 105 902 349565 NMNAT3 META_PWY66-162 ethanol degradation IV 0.310451719489736 -1.16972688248554 3 1 0.00952380952380952 105 902 217 ALDH2 META_PWY-6318 L-phenylalanine degradation IV (mammalian, via side chain) 0.310451719489736 -1.16972688248554 3 1 0.00952380952380952 105 902 217 ALDH2 META_PWY-7177 UTP and CTP dephosphorylation II 0.310451719489736 -1.16972688248554 3 1 0.00952380952380952 105 902 953 ENTPD1 META_PWY-7049 icosapentaenoate biosynthesis II (6-desaturase, mammals) 0.310451719489736 -1.16972688248554 3 1 0.00952380952380952 105 902 2180 ACSL1 META_PWY66-425 L-lysine degradation II (L-pipecolate pathway) 0.310451719489736 -1.16972688248554 3 1 0.00952380952380952 105 902 5831 PYCR1 HUMAN_PWY-6609 adenine and adenosine salvage III 0.310451719489736 -1.16972688248554 3 1 0.00952380952380952 105 902 4860 PNP META_PWY66-161 oxidative ethanol degradation III 0.310451719489736 -1.16972688248554 3 1 0.00952380952380952 105 902 217 ALDH2 META_PWY-5661 GDP-glucose biosynthesis 0.310451719489736 -1.16972688248554 3 1 0.00952380952380952 105 902 3098 HK1 HUMAN_PWY0-1296 purine ribonucleosides degradation to ribose-1-phosphate 0.310451719489736 -1.16972688248554 3 1 0.00952380952380952 105 902 4860 PNP HUMAN_PWY66-387 fatty acid alpha-oxidation 0.310451719489736 -1.16972688248554 3 1 0.00952380952380952 105 902 11001 SLC27A2 HUMAN_GLYCLEAV-PWY glycine cleavage 0.310451719489736 -1.16972688248554 3 1 0.00952380952380952 105 902 2731 GLDC META_PWY-7724 icosapentaenoate biosynthesis III (8-desaturase, mammals) 0.310451719489736 -1.16972688248554 3 1 0.00952380952380952 105 902 2180 ACSL1 HUMAN_GLUDEG-I-PWY GABA shunt 0.310451719489736 -1.16972688248554 3 1 0.00952380952380952 105 902 18 ABAT HUMAN_PWY-5661-1 GDP-glucose biosynthesis II 0.310451719489736 -1.16972688248554 3 1 0.00952380952380952 105 902 3098 HK1 META_GLYCINE-SYN2-PWY glycine biosynthesis II 0.310451719489736 -1.16972688248554 3 1 0.00952380952380952 105 902 2731 GLDC META_PWY-7185 UTP and CTP dephosphorylation I 0.310451719489736 -1.16972688248554 3 1 0.00952380952380952 105 902 953 ENTPD1 META_PWY66-387 fatty acid alpha-oxidation II 0.310451719489736 -1.16972688248554 3 1 0.00952380952380952 105 902 11001 SLC27A2 HUMAN_PWY-6608 guanosine nucleotides degradation 0.310451719489736 -1.16972688248554 3 1 0.00952380952380952 105 902 4860 PNP META_PWY-6558 heparan sulfate biosynthesis (late stages) 0.316524609306636 -1.1503542858973 17 3 0.0285714285714286 105 902 9953,266722,26035 HS3ST3B1,HS6ST3,GLCE HUMAN_PWY-6398 melatonin degradation I 0.327857832572445 -1.11517520183821 10 2 0.019047619047619 105 902 113612,1545 CYP2U1,CYP1B1 HUMAN_PWY-7049 icosapentaenoate biosynthesis II (metazoa) 0.327857832572445 -1.11517520183821 10 2 0.019047619047619 105 902 2180,6296 ACSL1,ACSM3 META_PWY-5004 superpathway of L-citrulline metabolism 0.372626422849405 -0.987178908542603 11 2 0.019047619047619 105 902 445,4846 ASS1,NOS3 HUMAN_PWY-6309 L-kynurenine degradation 0.372626422849405 -0.987178908542603 11 2 0.019047619047619 105 902 6999,8564 TDO2,KMO HUMAN_PWY-5972 stearate biosynthesis 0.372626422849405 -0.987178908542603 11 2 0.019047619047619 105 902 2180,11001 ACSL1,SLC27A2 HUMAN_PWY-4061 glutathione-mediated detoxification 0.384027479838218 -0.95704116687616 19 3 0.0285714285714286 105 902 2947,2948,4259 GSTM3,GSTM4,MGST3 META_PWY-6368 3-phosphoinositide degradation 0.384027479838218 -0.95704116687616 19 3 0.0285714285714286 105 902 22876,3636,8821 INPP5F,INPPL1,INPP4B HUMAN_PWY-5667 CDP-diacylglycerol biosynthesis 0.384027479838218 -0.95704116687616 19 3 0.0285714285714286 105 902 129642,56895,1040 MBOAT2,AGPAT4,CDS1 HUMAN_PWY-7219 adenosine ribonucleotides de novo biosynthesis 0.384027479838218 -0.95704116687616 19 3 0.0285714285714286 105 902 205,203,122622 AK4,AK1,ADSSL1 META_PWY66-368 ketolysis 0.390988504200318 -0.939077120451193 4 1 0.00952380952380952 105 902 56898 BDH2 HUMAN_PWY-5123 trans, trans-farnesyl diphosphate biosynthesis 0.390988504200318 -0.939077120451193 4 1 0.00952380952380952 105 902 3422 IDI1 HUMAN_PWY66-368 ketolysis 0.390988504200318 -0.939077120451193 4 1 0.00952380952380952 105 902 56898 BDH2 HUMAN_PWY-6568 dermatan sulfate biosynthesis (late stages) 0.390988504200318 -0.939077120451193 4 1 0.00952380952380952 105 902 10090 UST META_PWY-5123 trans, trans-farnesyl diphosphate biosynthesis 0.390988504200318 -0.939077120451193 4 1 0.00952380952380952 105 902 3422 IDI1 HUMAN_PWY-7177 UTP and CTP dephosphorylation II 0.390988504200318 -0.939077120451193 4 1 0.00952380952380952 105 902 953 ENTPD1 HUMAN_PWY-6292 cysteine biosynthesis 0.390988504200318 -0.939077120451193 4 1 0.00952380952380952 105 902 875 CBS META_PWY-7181 pyrimidine deoxyribonucleosides degradation 0.390988504200318 -0.939077120451193 4 1 0.00952380952380952 105 902 1890 TYMP META_PWY-6608 guanosine nucleotides degradation III 0.390988504200318 -0.939077120451193 4 1 0.00952380952380952 105 902 4860 PNP HUMAN_PWY66-21 ethanol degradation II 0.390988504200318 -0.939077120451193 4 1 0.00952380952380952 105 902 217 ALDH2 HUMAN_PWY66-162 ethanol degradation IV 0.390988504200318 -0.939077120451193 4 1 0.00952380952380952 105 902 217 ALDH2 HUMAN_PWY-5874 heme degradation 0.390988504200318 -0.939077120451193 4 1 0.00952380952380952 105 902 645 BLVRB META_PWY-6061 bile acid biosynthesis, neutral pathway 0.390988504200318 -0.939077120451193 4 1 0.00952380952380952 105 902 11001 SLC27A2 HUMAN_PWY-4984 urea cycle 0.390988504200318 -0.939077120451193 4 1 0.00952380952380952 105 902 445 ASS1 META_PWY-6568 dermatan sulfate biosynthesis (late stages) 0.390988504200318 -0.939077120451193 4 1 0.00952380952380952 105 902 10090 UST HUMAN_PWY66-425 lysine degradation II (pipecolate pathway) 0.390988504200318 -0.939077120451193 4 1 0.00952380952380952 105 902 5831 PYCR1 HUMAN_THIOREDOX-PWY thioredoxin pathway 0.390988504200318 -0.939077120451193 4 1 0.00952380952380952 105 902 114112 TXNRD3 META_PWY-5994 palmitate biosynthesis I (animals and fungi) 0.390988504200318 -0.939077120451193 4 1 0.00952380952380952 105 902 2194 FASN HUMAN_PWY-6358 superpathway of D-myo-inositol (1,4,5)-trisphosphate metabolism 0.417311785376913 -0.873921649806641 20 3 0.0285714285714286 105 902 22876,3636,3628 INPP5F,INPPL1,INPP1 HUMAN_PWY-6368 3-phosphoinositide degradation 0.417311785376913 -0.873921649806641 20 3 0.0285714285714286 105 902 22876,3636,8821 INPP5F,INPPL1,INPP4B META_PWY-5189 tetrapyrrole biosynthesis II (from glycine) 0.462198088899492 -0.771761715941639 5 1 0.00952380952380952 105 902 7390 UROS META_PWY-5667 CDP-diacylglycerol biosynthesis I 0.462198088899492 -0.771761715941639 5 1 0.00952380952380952 105 902 56895 AGPAT4 META_PWY-7433 mucin core 1 and core 2 O-glycosylation 0.462198088899492 -0.771761715941639 5 1 0.00952380952380952 105 902 2589 GALNT1 HUMAN_PWY-7181 pyrimidine deoxyribonucleosides degradation 0.462198088899492 -0.771761715941639 5 1 0.00952380952380952 105 902 1890 TYMP META_PWY-7606 docosahexaenoate biosynthesis III (6-desaturase, mammals) 0.462198088899492 -0.771761715941639 5 1 0.00952380952380952 105 902 1962 EHHADH META_SALVADEHYPOX-PWY adenosine nucleotides degradation II 0.462198088899492 -0.771761715941639 5 1 0.00952380952380952 105 902 4860 PNP HUMAN_PWY66-367 ketogenesis 0.462198088899492 -0.771761715941639 5 1 0.00952380952380952 105 902 56898 BDH2 META_PWY-6342 noradrenaline and adrenaline degradation 0.462198088899492 -0.771761715941639 5 1 0.00952380952380952 105 902 217 ALDH2 META_PWY-6398 melatonin degradation I 0.462198088899492 -0.771761715941639 5 1 0.00952380952380952 105 902 1545 CYP1B1 META_VALDEG-PWY L-valine degradation I 0.462198088899492 -0.771761715941639 5 1 0.00952380952380952 105 902 18 ABAT META_PWY-6402 superpathway of melatonin degradation 0.462198088899492 -0.771761715941639 5 1 0.00952380952380952 105 902 1545 CYP1B1 HUMAN_PWY66-161 oxidative ethanol degradation III 0.462198088899492 -0.771761715941639 5 1 0.00952380952380952 105 902 217 ALDH2 META_PWY-7726 (4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis (6-desaturase) 0.462198088899492 -0.771761715941639 5 1 0.00952380952380952 105 902 1962 EHHADH HUMAN_PLPSAL-PWY pyridoxal 5'-phosphate salvage 0.462198088899492 -0.771761715941639 5 1 0.00952380952380952 105 902 151230 KLHL23 HUMAN_PWY66-241 bupropion degradation 0.462198088899492 -0.771761715941639 5 1 0.00952380952380952 105 902 113612 CYP2U1 HUMAN_PWY-5189 tetrapyrrole biosynthesis 0.462198088899492 -0.771761715941639 5 1 0.00952380952380952 105 902 7390 UROS HUMAN_PWY-5030 histidine degradation 0.462198088899492 -0.771761715941639 5 1 0.00952380952380952 105 902 144193 AMDHD1 META_PWY-4984 urea cycle 0.462198088899492 -0.771761715941639 5 1 0.00952380952380952 105 902 445 ASS1 HUMAN_PWY-5966-1 fatty acid biosynthesis initiation 0.462198088899492 -0.771761715941639 5 1 0.00952380952380952 105 902 2194 FASN HUMAN_FAO-PWY fatty acid beta-oxidation 0.49843367159483 -0.696284754411251 14 2 0.019047619047619 105 902 2180,11001 ACSL1,SLC27A2 HUMAN_PWY3DJ-12 ceramide de novo biosynthesis 0.525151489865482 -0.644068505888944 6 1 0.00952380952380952 105 902 10715 CERS1 META_PWY66-367 ketogenesis 0.525151489865482 -0.644068505888944 6 1 0.00952380952380952 105 902 3157 HMGCS1 META_PWY3DJ-12 ceramide de novo biosynthesis 0.525151489865482 -0.644068505888944 6 1 0.00952380952380952 105 902 10715 CERS1 HUMAN_PWY-5996 oleate biosynthesis 0.525151489865482 -0.644068505888944 6 1 0.00952380952380952 105 902 6319 SCD META_PWY-5695 urate biosynthesis/inosine 5'-phosphate degradation 0.525151489865482 -0.644068505888944 6 1 0.00952380952380952 105 902 4860 PNP META_PWY-7277 sphingolipid biosynthesis (mammals) 0.525151489865482 -0.644068505888944 6 1 0.00952380952380952 105 902 10715 CERS1 META_PWY-5327 superpathway of L-lysine degradation 0.525151489865482 -0.644068505888944 6 1 0.00952380952380952 105 902 10157 AASS HUMAN_PWY-5695 urate biosynthesis/inosine 5'-phosphate degradation 0.525151489865482 -0.644068505888944 6 1 0.00952380952380952 105 902 4860 PNP HUMAN_PWY66-221 nicotine degradation III 0.58079779964855 -0.543352603962629 7 1 0.00952380952380952 105 902 113612 CYP2U1 HUMAN_PWY-5994 palmitate biosynthesis 0.58079779964855 -0.543352603962629 7 1 0.00952380952380952 105 902 2194 FASN META_PWY-6567 chondroitin sulfate biosynthesis (late stages) 0.58079779964855 -0.543352603962629 7 1 0.00952380952380952 105 902 10090 UST HUMAN_PWY66-407 superpathway of conversion of glucose to acetyl CoA and entry into the TCA cycle 0.620935620986813 -0.476527872331269 36 4 0.0380952380952381 105 902 3098,2026,230,226 HK1,ENO2,ALDOC,ALDOA HUMAN_PWY-6352 3-phosphoinositide biosynthesis 0.626723471788746 -0.467249869462991 27 3 0.0285714285714286 105 902 5287,138429,9896 PIK3C2B,PIP5KL1,FIG4 HUMAN_PWY-6567 chondroitin sulfate biosynthesis (late stages) 0.629977946059863 -0.462070466463478 8 1 0.00952380952380952 105 902 10090 UST META_PWY-5920 superpathway of heme biosynthesis from glycine 0.629977946059863 -0.462070466463478 8 1 0.00952380952380952 105 902 7390 UROS HUMAN_SALVADEHYPOX-PWY adenosine nucleotides degradation 0.629977946059863 -0.462070466463478 8 1 0.00952380952380952 105 902 4860 PNP HUMAN_PWY-5451 acetone degradation I (to methylglyoxal) 0.629977946059863 -0.462070466463478 8 1 0.00952380952380952 105 902 113612 CYP2U1 HUMAN_PWY-5920 heme biosynthesis 0.629977946059863 -0.462070466463478 8 1 0.00952380952380952 105 902 7390 UROS HUMAN_PWY66-409 superpathway of purine nucleotide salvage 0.66506528884722 -0.407870064427874 38 4 0.0380952380952381 105 902 205,203,4860,122622 AK4,AK1,PNP,ADSSL1 META_PWY-6358 superpathway of D-myo-inositol (1,4,5)-trisphosphate metabolism 0.669367691395568 -0.40142175638977 19 2 0.019047619047619 105 902 3636,3628 INPPL1,INPP1 HUMAN_PWY-7205 CMP phosphorylation 0.673436912128645 -0.395360959191573 9 1 0.00952380952380952 105 902 129607 CMPK2 HUMAN_PWY3DJ-11470 sphingosine and sphingosine-1-phosphate metabolism 0.673436912128645 -0.395360959191573 9 1 0.00952380952380952 105 902 340485 ACER2 META_PWY-6353 purine nucleotides degradation II (aerobic) 0.673436912128645 -0.395360959191573 9 1 0.00952380952380952 105 902 4860 PNP HUMAN_PWY-6353 purine nucleotides degradation 0.711834587636166 -0.339909715296526 10 1 0.00952380952380952 105 902 4860 PNP HUMAN_PWY66-201 nicotine degradation IV 0.711834587636166 -0.339909715296526 10 1 0.00952380952380952 105 902 113612 CYP2U1 HUMAN_PWY-7197 pyrimidine deoxyribonucleotide phosphorylation 0.711834587636166 -0.339909715296526 10 1 0.00952380952380952 105 902 129607 CMPK2 META_PWY-6363 D-myo-inositol (1,4,5)-trisphosphate degradation 0.745755404115137 -0.293357609062899 11 1 0.00952380952380952 105 902 3628 INPP1 HUMAN_LIPAS-PWY triacylglycerol degradation 0.745755404115137 -0.293357609062899 11 1 0.00952380952380952 105 902 57406 ABHD6 HUMAN_PWY-7176 UTP and CTP de novo biosynthesis 0.745755404115137 -0.293357609062899 11 1 0.00952380952380952 105 902 129607 CMPK2 HUMAN_VALDEG-PWY valine degradation 0.775716888481941 -0.253967659797679 12 1 0.00952380952380952 105 902 18 ABAT META_PWY-6857 retinol biosynthesis 0.775716888481941 -0.253967659797679 12 1 0.00952380952380952 105 902 9227 LRAT HUMAN_PWY-6061 bile acid biosynthesis, neutral pathway 0.775716888481941 -0.253967659797679 12 1 0.00952380952380952 105 902 11001 SLC27A2 HUMAN_PWY0-162 superpathway of pyrimidine ribonucleotides de novo biosynthesis 0.802177255574029 -0.220425678611042 13 1 0.00952380952380952 105 902 129607 CMPK2 META_PWY66-409 superpathway of purine nucleotide salvage 0.802177255574029 -0.220425678611042 13 1 0.00952380952380952 105 902 4860 PNP META_PWY-6861 the visual cycle I (vertebrates) 0.802177255574029 -0.220425678611042 13 1 0.00952380952380952 105 902 9227 LRAT HUMAN_PWY-5328 superpathway of methionine degradation 0.802177255574029 -0.220425678611042 13 1 0.00952380952380952 105 902 875 CBS META_PWY-5328 superpathway of L-methionine salvage and degradation 0.802177255574029 -0.220425678611042 13 1 0.00952380952380952 105 902 875 CBS META_PWY-6352 3-phosphoinositide biosynthesis 0.809483144441366 -0.211359328266079 25 2 0.019047619047619 105 902 5287,9896 PIK3C2B,FIG4 HUMAN_PWY-841 purine nucleotides de novo biosynthesis 0.826850907854039 -0.190130880919504 37 3 0.0285714285714286 105 902 205,203,122622 AK4,AK1,ADSSL1 HUMAN_PWY-6861 the visual cycle I (vertebrates) 0.84617060904233 -0.167034274173006 15 1 0.00952380952380952 105 902 9227 LRAT HUMAN_PWY-6362 1D-myo-inositol hexakisphosphate biosynthesis II (mammalian) 0.84617060904233 -0.167034274173006 15 1 0.00952380952380952 105 902 3636 INPPL1 META_PWY-6362 1D-myo-inositol hexakisphosphate biosynthesis II (mammalian) 0.84617060904233 -0.167034274173006 15 1 0.00952380952380952 105 902 3636 INPPL1 HUMAN_PWY-6364 D-myo-inositol (1,3,4)-trisphosphate biosynthesis 0.84617060904233 -0.167034274173006 15 1 0.00952380952380952 105 902 3636 INPPL1 META_PWY-6364 D-myo-inositol (1,3,4)-trisphosphate biosynthesis 0.84617060904233 -0.167034274173006 15 1 0.00952380952380952 105 902 3636 INPPL1 HUMAN_PWY-7200 superpathway of pyrimidine deoxyribonucleoside salvage 0.84617060904233 -0.167034274173006 15 1 0.00952380952380952 105 902 129607 CMPK2 HUMAN_PWY-6857 retinol biosynthesis 0.880452701693271 -0.127319070043207 17 1 0.00952380952380952 105 902 9227 LRAT HUMAN_PWY-7211 superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis 0.918192111435565 -0.0853486385396163 20 1 0.00952380952380952 105 902 129607 CMPK2 HUMAN_PWY-6351 D-myo-inositol (1,4,5)-trisphosphate biosynthesis 0.944094767161565 -0.0575287289329327 23 1 0.00952380952380952 105 902 138429 PIP5KL1 HUMAN_PWY-6371 superpathway of inositol phosphate compounds 0.962344745367955 -0.0383825293448218 66 4 0.0380952380952381 105 902 138429,5287,9896,3636 PIP5KL1,PIK3C2B,FIG4,INPPL1 HUMAN_LIPASYN-PWY phospholipases 0.974001093503996 -0.0263428526461907 29 1 0.00952380952380952 105 902 5337 PLD1 HUMAN_PWY0-1313 acetate conversion to acetyl-CoA 0.99999999999684 -3.15971554476491e-12 2 0 0 105 902 HUMAN_PWY-6365 D-myo-inositol (3,4,5,6)-tetrakisphosphate biosynthesis 0.99999999999684 -3.15971554476491e-12 2 0 0 105 902 HUMAN_PROPIONMET-PWY propionyl-CoA degradation 0.99999999999684 -3.15971554476491e-12 2 0 0 105 902 META_PWY-6076 vitamin D3 biosynthesis 0.99999999999684 -3.15971554476491e-12 2 0 0 105 902 META_CHOLINE-BETAINE-ANA-PWY choline degradation I 0.99999999999684 -3.15971554476491e-12 2 0 0 105 902 HUMAN_PWY0-662 PRPP biosynthesis 0.99999999999684 -3.15971554476491e-12 2 0 0 105 902 HUMAN_PWY-6076 vitamin D3 biosynthesis 0.99999999999684 -3.15971554476491e-12 2 0 0 105 902 META_PWY-6117 spermine and spermidine degradation I 0.99999999999684 -3.15971554476491e-12 2 0 0 105 902 HUMAN_GLYSYN-ALA-PWY glycine biosynthesis 0.99999999999684 -3.15971554476491e-12 2 0 0 105 902 META_PWY-4041 gamma-glutamyl cycle 0.99999999999684 -3.15971554476491e-12 2 0 0 105 902 META_PROPIONMET-PWY propanoyl CoA degradation I 0.99999999999684 -3.15971554476491e-12 2 0 0 105 902 META_PWY66-394 aspirin triggered resolvin E biosynthesis 0.99999999999684 -3.15971554476491e-12 2 0 0 105 902 META_PWY66-397 resolvin D biosynthesis 0.99999999999684 -3.15971554476491e-12 2 0 0 105 902 META_PWY-5340 sulfate activation for sulfonation 0.99999999999684 -3.15971554476491e-12 2 0 0 105 902 HUMAN_PWY-6121 5-aminoimidazole ribonucleotide biosynthesis 0.99999999999684 -3.15971554476491e-12 2 0 0 105 902 META_PWY-6613 tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate 0.99999999999684 -3.15971554476491e-12 2 0 0 105 902 HUMAN_PWY66-388 fatty acid alpha-oxidation III 0.99999999999684 -3.15971554476491e-12 2 0 0 105 902 META_PWY-7437 protein O-[N-acetyl]-glucosylation 0.99999999999684 -3.15971554476491e-12 2 0 0 105 902 HUMAN_PWY-6118 glycerol-3-phosphate shuttle 0.99999999999684 -3.15971554476491e-12 2 0 0 105 902 META_PWY0-1295 pyrimidine ribonucleosides degradation 0.99999999999684 -3.15971554476491e-12 2 0 0 105 902 META_PWY-6688 thyronamine and iodothyronamine metabolism 0.99999999999684 -3.15971554476491e-12 2 0 0 105 902 HUMAN_PWY66-301 catecholamine biosynthesis 0.99999999999684 -3.15971554476491e-12 2 0 0 105 902 META_PWY66-366 flavin biosynthesis IV (mammalian) 0.99999999999684 -3.15971554476491e-12 2 0 0 105 902 META_PWY-6138 CMP-N-acetylneuraminate biosynthesis I (eukaryotes) 0.99999999999684 -3.15971554476491e-12 2 0 0 105 902 HUMAN_PWY-6566 chondroitin biosynthesis 0.99999999999684 -3.15971554476491e-12 2 0 0 105 902 META_PWY-5874 heme degradation 0.99999999999684 -3.15971554476491e-12 2 0 0 105 902 HUMAN_PWY-7286 7-(3-amino-3-carboxypropyl)-wyosine biosynthesis 0.99999999999684 -3.15971554476491e-12 2 0 0 105 902 META_PWY-6121 5-aminoimidazole ribonucleotide biosynthesis I 0.99999999999684 -3.15971554476491e-12 2 0 0 105 902 META_PWY-6365 D-myo-inositol (3,4,5,6)-tetrakisphosphate biosynthesis 0.99999999999684 -3.15971554476491e-12 2 0 0 105 902 HUMAN_PWY-5905 hypusine biosynthesis 0.99999999999684 -3.15971554476491e-12 2 0 0 105 902 META_PWY-6118 glycerol-3-phosphate shuttle 0.99999999999684 -3.15971554476491e-12 2 0 0 105 902 HUMAN_PWY-5686 UMP biosynthesis 0.99999999999684 -3.15971554476491e-12 2 0 0 105 902 HUMAN_PWY66-397 resolvin D biosynthesis 0.99999999999684 -3.15971554476491e-12 2 0 0 105 902 HUMAN_PWY-6241 thyroid hormone biosynthesis 0.99999999999684 -3.15971554476491e-12 2 0 0 105 902 HUMAN_PWY-5481 lactate fermentation (reoxidation of cytosolic NADH) 0.99999999999684 -3.15971554476491e-12 2 0 0 105 902 HUMAN_PWY66-14 MAP kinase cascade 0.99999999999684 -3.15971554476491e-12 2 0 0 105 902 HUMAN_PWY-5340 sulfate activation for sulfonation 0.99999999999684 -3.15971554476491e-12 2 0 0 105 902 META_PLPSAL-PWY pyridoxal 5'-phosphate salvage I 0.99999999999684 -3.15971554476491e-12 2 0 0 105 902 HUMAN_PWY-7437 protein O-[N-acetyl]-glucosylation 0.99999999999684 -3.15971554476491e-12 2 0 0 105 902 HUMAN_ASPARTATESYN-PWY aspartate biosynthesis 0.99999999999684 -3.15971554476491e-12 2 0 0 105 902 HUMAN_PWY0-1182 trehalose degradation 0.99999999999684 -3.15971554476491e-12 2 0 0 105 902 HUMAN_PWY0-1275 lipoate biosynthesis and incorporation 0.99999999999684 -3.15971554476491e-12 2 0 0 105 902 HUMAN_GLUTAMINDEG-PWY glutamine degradation/glutamate biosynthesis 0.99999999999684 -3.15971554476491e-12 2 0 0 105 902 META_PWY-5030 L-histidine degradation III 0.99999999999684 -3.15971554476491e-12 2 0 0 105 902 HUMAN_PWY-6688 thyronamine and iodothyronamine metabolism 0.99999999999684 -3.15971554476491e-12 2 0 0 105 902 META_PWY-5806 all-trans-decaprenyl diphosphate biosynthesis 0.99999999999684 -3.15971554476491e-12 2 0 0 105 902 META_PWY-6124 inosine-5'-phosphate biosynthesis II 0.99999999999684 -3.15971554476491e-12 2 0 0 105 902 META_PWY66-395 aspirin triggered resolvin D biosynthesis 0.99999999999684 -3.15971554476491e-12 2 0 0 105 902 HUMAN_PWY66-393 aspirin-triggered lipoxin biosynthesis 0.99999999999684 -3.15971554476491e-12 2 0 0 105 902 META_SER-GLYSYN-PWY superpathway of L-serine and glycine biosynthesis I 0.99999999999684 -3.15971554476491e-12 2 0 0 105 902 HUMAN_PWY-6124 inosine-5'-phosphate biosynthesis 0.99999999999684 -3.15971554476491e-12 2 0 0 105 902 HUMAN_PWY-6613 tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate 0.99999999999684 -3.15971554476491e-12 2 0 0 105 902 HUMAN_PWY66-394 aspirin triggered resolvin E biosynthesis 0.99999999999684 -3.15971554476491e-12 2 0 0 105 902 HUMAN_PWY-6138 CMP-N-acetylneuraminate biosynthesis I (eukaryotes) 0.99999999999684 -3.15971554476491e-12 2 0 0 105 902 HUMAN_PWY66-395 aspirin triggered resolvin D biosynthesis 0.99999999999684 -3.15971554476491e-12 2 0 0 105 902 HUMAN_PWY-6012-1 acyl carrier protein metabolism 0.99999999999684 -3.15971554476491e-12 2 0 0 105 902 HUMAN_PWY-6482 diphthamide biosynthesis 0.99999999999684 -3.15971554476491e-12 2 0 0 105 902 HUMAN_CYSTEINE-DEG-PWY L-cysteine degradation I 0.99999999999684 -3.15971554476491e-12 2 0 0 105 902 HUMAN_PWY-5269 cardiolipin biosynthesis 0.99999999999684 -3.15971554476491e-12 2 0 0 105 902 HUMAN_PWY-6181 histamine degradation 0.99999999999684 -3.15971554476491e-12 2 0 0 105 902 META_PWY0-662 PRPP biosynthesis I 0.99999999999684 -3.15971554476491e-12 2 0 0 105 902 META_PWY66-393 aspirin-triggered lipoxin biosynthesis 0.99999999999684 -3.15971554476491e-12 2 0 0 105 902 META_PWY-5177 glutaryl-CoA degradation 0.99999999999684 -3.15971554476491e-12 2 0 0 105 902 META_SERDEG-PWY L-serine degradation 0.99999999999684 -3.15971554476491e-12 2 0 0 105 902 META_PWY-6145 superpathway of CMP-sialic acids biosynthesis 0.99999999999684 -3.15971554476491e-12 2 0 0 105 902 HUMAN_PWY-6260 thyroid hormone metabolism I (via deiodination) 0.99999999999684 -3.15971554476491e-12 2 0 0 105 902 META_PWY-5453 methylglyoxal degradation III 0.99999999999684 -3.15971554476491e-12 2 0 0 105 902 META_PWY-5505 L-glutamate and L-glutamine biosynthesis 0.99999999999684 -3.15971554476491e-12 2 0 0 105 902 META_PROUT-PWY L-proline degradation 0.99999999999684 -3.15971554476491e-12 2 0 0 105 902 HUMAN_GLYSYN-PWY glycine/serine biosynthesis 0.99999999999684 -3.15971554476491e-12 2 0 0 105 902 HUMAN_PWY-6 GDP-L-fucose biosynthesis II (from L-fucose) 0.99999999999684 -3.15971554476491e-12 2 0 0 105 902 META_PWY-7343 UDP-glucose biosynthesis 0.99999999999684 -3.15971554476491e-12 2 0 0 105 902 HUMAN_PWY-2301 myo-inositol de novo biosynthesis 0.99999999999684 -3.15971554476491e-12 2 0 0 105 902 HUMAN_CHOLINE-BETAINE-ANA-PWY choline degradation 0.99999999999684 -3.15971554476491e-12 2 0 0 105 902 META_UDPNACETYLGALSYN-PWY UDP-N-acetyl-D-glucosamine biosynthesis II 0.99999999999684 -3.15971554476491e-12 2 0 0 105 902 META_PWY-6260 thyroid hormone metabolism I (via deiodination) 0.99999999999684 -3.15971554476491e-12 2 0 0 105 902 META_PWY-6181 histamine degradation 0.99999999999684 -3.15971554476491e-12 2 0 0 105 902 META_PWY66-382 mineralocorticoid biosynthesis 0.999999999999463 -5.36924888230872e-13 3 0 0 105 902 META_ADENOSYLHOMOCYSCAT-PWY L-methionine salvage from L-homocysteine 0.999999999999463 -5.36924888230872e-13 3 0 0 105 902 META_PWY-5996 oleate biosynthesis II (animals and fungi) 0.999999999999463 -5.36924888230872e-13 3 0 0 105 902 HUMAN_PWY-5331 taurine biosynthesis 0.999999999999463 -5.36924888230872e-13 3 0 0 105 902 META_PWY-5664 tetrahydrobiopterin biosynthesis II 0.999999999999463 -5.36924888230872e-13 3 0 0 105 902 HUMAN_PWY-7193 pyrimidine ribonucleosides salvage I 0.999999999999463 -5.36924888230872e-13 3 0 0 105 902 HUMAN_PWY66-381 glucocorticoid biosynthesis 0.999999999999463 -5.36924888230872e-13 3 0 0 105 902 META_PWY-5084 2-oxoglutarate decarboxylation to succinyl-CoA 0.999999999999463 -5.36924888230872e-13 3 0 0 105 902 META_PWY-5331 taurine biosynthesis 0.999999999999463 -5.36924888230872e-13 3 0 0 105 902 META_ARGININE-SYN4-PWY L-ornithine biosynthesis II 0.999999999999463 -5.36924888230872e-13 3 0 0 105 902 HUMAN_PWY-6366 D-myo-inositol (1,4,5,6)-tetrakisphosphate biosynthesis 0.999999999999463 -5.36924888230872e-13 3 0 0 105 902 META_PWY-6405 Rapoport-Luebering glycolytic shunt 0.999999999999463 -5.36924888230872e-13 3 0 0 105 902 HUMAN_PWY0-1295 pyrimidine ribonucleosides degradation 0.999999999999463 -5.36924888230872e-13 3 0 0 105 902 META_ASPARAGINE-DEG1-PWY-1 L-asparagine degradation III (mammalian) 0.999999999999463 -5.36924888230872e-13 3 0 0 105 902 HUMAN_PWY-6158 creatine-phosphate biosynthesis 0.999999999999463 -5.36924888230872e-13 3 0 0 105 902 META_MALATE-ASPARTATE-SHUTTLE-PWY L-aspartate degradation II 0.999999999999463 -5.36924888230872e-13 3 0 0 105 902 META_PWY66-392 lipoxin biosynthesis 0.999999999999463 -5.36924888230872e-13 3 0 0 105 902 HUMAN_PWY66-382 mineralocorticoid biosynthesis 0.999999999999463 -5.36924888230872e-13 3 0 0 105 902 HUMAN_ADENOSYLHOMOCYSCAT-PWY methionine salvage 0.999999999999463 -5.36924888230872e-13 3 0 0 105 902 META_PWY-7728 (4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase) 0.999999999999463 -5.36924888230872e-13 3 0 0 105 902 HUMAN_PWY-6430 thymine degradation 0.999999999999463 -5.36924888230872e-13 3 0 0 105 902 HUMAN_OXIDATIVEPENT-PWY-1 pentose phosphate pathway (oxidative branch) 0.999999999999463 -5.36924888230872e-13 3 0 0 105 902 META_PWY66-381 glucocorticoid biosynthesis 0.999999999999463 -5.36924888230872e-13 3 0 0 105 902 META_PWY66-301 catecholamine biosynthesis 0.999999999999463 -5.36924888230872e-13 3 0 0 105 902 META_PWY-7511 protein ubiquitylation 0.999999999999463 -5.36924888230872e-13 3 0 0 105 902 HUMAN_PWY-6100 L-carnitine biosynthesis 0.999999999999463 -5.36924888230872e-13 3 0 0 105 902 META_PWY-6875 retinoate biosynthesis II 0.999999999999463 -5.36924888230872e-13 3 0 0 105 902 HUMAN_PWY-5084 2-oxoglutarate decarboxylation to succinyl-CoA 0.999999999999463 -5.36924888230872e-13 3 0 0 105 902 HUMAN_PWY-7185 UTP and CTP dephosphorylation I 0.999999999999463 -5.36924888230872e-13 3 0 0 105 902 META_PWY-6366 D-myo-inositol (1,4,5,6)-tetrakisphosphate biosynthesis 0.999999999999463 -5.36924888230872e-13 3 0 0 105 902 META_ARGASEDEG-PWY L-arginine degradation I (arginase pathway) 0.999999999999463 -5.36924888230872e-13 3 0 0 105 902 HUMAN_PWY-3982 uracil degradation 0.999999999999463 -5.36924888230872e-13 3 0 0 105 902 HUMAN_METHIONINE-DEG1-PWY methionine degradation 0.999999999999463 -5.36924888230872e-13 3 0 0 105 902 HUMAN_PWY-6554 1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3) 0.999999999999463 -5.36924888230872e-13 3 0 0 105 902 META_PWY-6100 L-carnitine biosynthesis 0.999999999999463 -5.36924888230872e-13 3 0 0 105 902 META_PWY-5451 acetone degradation I (to methylglyoxal) 0.999999999999463 -5.36924888230872e-13 3 0 0 105 902 META_PWY-5663 tetrahydrobiopterin biosynthesis I 0.999999999999463 -5.36924888230872e-13 3 0 0 105 902 HUMAN_PWY66-385 dTMP de novo biosynthesis (mitochondrial) 0.999999999999463 -5.36924888230872e-13 3 0 0 105 902 HUMAN_PWY-5663 tetrahydrobiopterin de novo biosynthesis 0.999999999999463 -5.36924888230872e-13 3 0 0 105 902 META_PWY-2301 myo-inositol biosynthesis 0.999999999999463 -5.36924888230872e-13 3 0 0 105 902 META_PHENYLALANINE-DEG1-PWY L-phenylalanine degradation I (aerobic) 0.999999999999463 -5.36924888230872e-13 3 0 0 105 902 META_PWY-7193 pyrimidine ribonucleosides salvage I 0.999999999999463 -5.36924888230872e-13 3 0 0 105 902 META_PWY-7727 docosahexaenoate biosynthesis IV (4-desaturase, mammals) 0.999999999999463 -5.36924888230872e-13 3 0 0 105 902 META_PWY-7527 L-methionine salvage cycle III 0.999999999999463 -5.36924888230872e-13 3 0 0 105 902 META_HEME-BIOSYNTHESIS-II heme biosynthesis I (aerobic) 0.999999999999463 -5.36924888230872e-13 3 0 0 105 902 META_OXIDATIVEPENT-PWY pentose phosphate pathway (oxidative branch) 0.999999999999463 -5.36924888230872e-13 3 0 0 105 902 HUMAN_NONOXIPENT-PWY pentose phosphate pathway (non-oxidative branch) 0.999999999999463 -5.36924888230872e-13 3 0 0 105 902 HUMAN_GLUAMCAT-PWY N-acetylglucosamine degradation I 0.999999999999463 -5.36924888230872e-13 3 0 0 105 902 HUMAN_ARGININE-SYN4-PWY ornithine de novo biosynthesis 0.999999999999463 -5.36924888230872e-13 3 0 0 105 902 META_PWY-3982 uracil degradation I (reductive) 0.999999999999463 -5.36924888230872e-13 3 0 0 105 902 META_PWY-7466 acetone degradation III (to propane-1,2-diol) 0.999999999999463 -5.36924888230872e-13 3 0 0 105 902 HUMAN_HEME-BIOSYNTHESIS-II heme biosynthesis from uroporphyrinogen-III I 0.999999999999463 -5.36924888230872e-13 3 0 0 105 902 HUMAN_PHENYLALANINE-DEG1-PWY phenylalanine degradation/tyrosine biosynthesis 0.999999999999463 -5.36924888230872e-13 3 0 0 105 902 HUMAN_SAM-PWY S-adenosyl-L-methionine biosynthesis 0.999999999999463 -5.36924888230872e-13 3 0 0 105 902 HUMAN_PWY-5453 methylglyoxal degradation III 0.999999999999463 -5.36924888230872e-13 3 0 0 105 902 HUMAN_PWY0-1264 biotin-carboxyl carrier protein assembly 0.999999999999463 -5.36924888230872e-13 3 0 0 105 902 META_PWY66-221 nicotine degradation V 0.999999999999463 -5.36924888230872e-13 3 0 0 105 902 HUMAN_PWY-6307 tryptophan degradation via tryptamine 0.999999999999463 -5.36924888230872e-13 3 0 0 105 902 HUMAN_PWY66-392 lipoxin biosynthesis 0.999999999999463 -5.36924888230872e-13 3 0 0 105 902 HUMAN_PWY-7283 wybutosine biosynthesis 0.999999999999463 -5.36924888230872e-13 3 0 0 105 902 HUMAN_PWY-7606 docosahexaenoate biosynthesis III (mammals) 0.999999999999463 -5.36924888230872e-13 3 0 0 105 902 META_PWY66-422 D-galactose degradation V (Leloir pathway) 0.999999999999463 -5.36924888230872e-13 3 0 0 105 902 META_PWY-6756 S-methyl-5'-thioadenosine degradation II 0.999999999999876 -1.24289467606786e-13 1 0 0 105 902 META_PWY-7625 phosphatidylinositol biosynthesis II (eukaryotes) 0.999999999999876 -1.24289467606786e-13 1 0 0 105 902 HUMAN_PWY-6133 (S)-reticuline biosynthesis 0.999999999999876 -1.24289467606786e-13 1 0 0 105 902 META_PWY66-421 homocarnosine biosynthesis 0.999999999999876 -1.24289467606786e-13 1 0 0 105 902 HUMAN_PWY-6405 Rapoport-Luebering glycolytic shunt 0.999999999999876 -1.24289467606786e-13 1 0 0 105 902 META_PWY-5329 L-cysteine degradation III 0.999999999999876 -1.24289467606786e-13 1 0 0 105 902 HUMAN_P121-PWY adenine and adenosine salvage I 0.999999999999876 -1.24289467606786e-13 1 0 0 105 902 META_ASPARTATESYN-PWY L-aspartate biosynthesis 0.999999999999876 -1.24289467606786e-13 1 0 0 105 902 META_PWY-6273 phosphatidylethanolamine biosynthesis III 0.999999999999876 -1.24289467606786e-13 1 0 0 105 902 META_PWY-5686 UMP biosynthesis 0.999999999999876 -1.24289467606786e-13 1 0 0 105 902 META_ALANINE-SYN2-PWY L-alanine biosynthesis II 0.999999999999876 -1.24289467606786e-13 1 0 0 105 902 HUMAN_PWY-5148 acyl-CoA hydrolysis 0.999999999999876 -1.24289467606786e-13 1 0 0 105 902 HUMAN_GLYCGREAT-PWY creatine biosynthesis 0.999999999999876 -1.24289467606786e-13 1 0 0 105 902 META_PWY-7250 [2Fe-2S] iron-sulfur cluster biosynthesis 0.999999999999876 -1.24289467606786e-13 1 0 0 105 902 META_PWY-5905 hypusine biosynthesis 0.999999999999876 -1.24289467606786e-13 1 0 0 105 902 HUMAN_PWY-7506 phosphatidylserine biosynthesis II 0.999999999999876 -1.24289467606786e-13 1 0 0 105 902 META_PWY-46 putrescine biosynthesis III 0.999999999999876 -1.24289467606786e-13 1 0 0 105 902 META_PWY-5512 UDP-N-acetyl-D-galactosamine biosynthesis I 0.999999999999876 -1.24289467606786e-13 1 0 0 105 902 HUMAN_PWY-5652 2-amino-3-carboxymuconate semialdehyde degradation to glutaryl-CoA 0.999999999999876 -1.24289467606786e-13 1 0 0 105 902 HUMAN_PWY-6132 lanosterol biosynthesis 0.999999999999876 -1.24289467606786e-13 1 0 0 105 902 HUMAN_PWY0-522 lipoate salvage 0.999999999999876 -1.24289467606786e-13 1 0 0 105 902 HUMAN_PWY-5120 geranylgeranyldiphosphate biosynthesis 0.999999999999876 -1.24289467606786e-13 1 0 0 105 902 META_PWY-6377 alpha-tocopherol degradation 0.999999999999876 -1.24289467606786e-13 1 0 0 105 902 META_GLYCGREAT-PWY creatine biosynthesis 0.999999999999876 -1.24289467606786e-13 1 0 0 105 902 META_PWY-5326 sulfite oxidation IV 0.999999999999876 -1.24289467606786e-13 1 0 0 105 902 META_GLUT-REDOX-PWY glutathione-glutaredoxin redox reactions 0.999999999999876 -1.24289467606786e-13 1 0 0 105 902 HUMAN_PWY-5754 4-hydroxybenzoate biosynthesis 0.999999999999876 -1.24289467606786e-13 1 0 0 105 902 HUMAN_BGALACT-PWY lactose degradation III 0.999999999999876 -1.24289467606786e-13 1 0 0 105 902 HUMAN_PWY-40 putrescine biosynthesis II 0.999999999999876 -1.24289467606786e-13 1 0 0 105 902 HUMAN_PWY-5512 UDP-N-acetyl-D-galactosamine biosynthesis I 0.999999999999876 -1.24289467606786e-13 1 0 0 105 902 META_PWY-7506 phosphatidylserine biosynthesis II 0.999999999999876 -1.24289467606786e-13 1 0 0 105 902 META_PWY-6012-1 acyl carrier protein activation 0.999999999999876 -1.24289467606786e-13 1 0 0 105 902 META_PWY-6938 NADH repair 0.999999999999876 -1.24289467606786e-13 1 0 0 105 902 HUMAN_PROUT-PWY proline degradation 0.999999999999876 -1.24289467606786e-13 1 0 0 105 902 META_PWY-6502 oxidized GTP and dGTP detoxification 0.999999999999876 -1.24289467606786e-13 1 0 0 105 902 HUMAN_ARGSPECAT-PWY spermine biosynthesis 0.999999999999876 -1.24289467606786e-13 1 0 0 105 902 META_PWY-7219 adenosine ribonucleotides de novo biosynthesis 0.999999999999876 -1.24289467606786e-13 1 0 0 105 902 META_PWY-5120 geranylgeranyl diphosphate biosynthesis 0.999999999999876 -1.24289467606786e-13 1 0 0 105 902 HUMAN_PWY-7592 arachidonate biosynthesis III (metazoa) 0.999999999999876 -1.24289467606786e-13 1 0 0 105 902 META_PWY-5754 4-hydroxybenzoate biosynthesis I (eukaryotes) 0.999999999999876 -1.24289467606786e-13 1 0 0 105 902 HUMAN_PWY-5326 sulfite oxidation 0.999999999999876 -1.24289467606786e-13 1 0 0 105 902 HUMAN_PWY0-1305 glutamate dependent acid resistance 0.999999999999876 -1.24289467606786e-13 1 0 0 105 902 META_GLNSYN-PWY L-glutamine biosynthesis I 0.999999999999876 -1.24289467606786e-13 1 0 0 105 902 HUMAN_PWY-4101 sorbitol degradation I 0.999999999999876 -1.24289467606786e-13 1 0 0 105 902 HUMAN_SERDEG-PWY L-serine degradation 0.999999999999876 -1.24289467606786e-13 1 0 0 105 902 META_PWY-7112 4-hydroxy-2-nonenal detoxification 0.999999999999876 -1.24289467606786e-13 1 0 0 105 902 META_PWY-1722 formate assimilation into 5,10-methylenetetrahydrofolate 0.999999999999876 -1.24289467606786e-13 1 0 0 105 902 META_PWY-40 putrescine biosynthesis I 0.999999999999876 -1.24289467606786e-13 1 0 0 105 902 META_PWY-6619 adenine and adenosine salvage VI 0.999999999999876 -1.24289467606786e-13 1 0 0 105 902 HUMAN_PWY66-421 homocarnosine biosynthesis 0.999999999999876 -1.24289467606786e-13 1 0 0 105 902 META_PWY-5766 L-glutamate degradation X 0.999999999999876 -1.24289467606786e-13 1 0 0 105 902 HUMAN_PWY-6173 histamine biosynthesis 0.999999999999876 -1.24289467606786e-13 1 0 0 105 902 HUMAN_PWY-6756 S-methyl-5'-thioadenosine degradation 0.999999999999876 -1.24289467606786e-13 1 0 0 105 902 META_PWY66-241 bupropion degradation 0.999999999999876 -1.24289467606786e-13 1 0 0 105 902 HUMAN_GLUTAMATE-SYN2-PWY glutamate biosynthesis/degradation 0.999999999999876 -1.24289467606786e-13 1 0 0 105 902 HUMAN_PWY66-366 flavin biosynthesis 0.999999999999876 -1.24289467606786e-13 1 0 0 105 902 HUMAN_PWY66-420 carnosine biosynthesis 0.999999999999876 -1.24289467606786e-13 1 0 0 105 902 META_PWY-7344 UDP-D-galactose biosynthesis 0.999999999999876 -1.24289467606786e-13 1 0 0 105 902 META_GLUTAMATE-SYN2-PWY L-glutamate biosynthesis II 0.999999999999876 -1.24289467606786e-13 1 0 0 105 902 META_HISHP-PWY L-histidine degradation VI 0.999999999999876 -1.24289467606786e-13 1 0 0 105 902 META_ARGSPECAT-PWY spermine biosynthesis 0.999999999999876 -1.24289467606786e-13 1 0 0 105 902 META_ALANINE-DEG3-PWY L-alanine degradation III 0.999999999999876 -1.24289467606786e-13 1 0 0 105 902 HUMAN_PWY-6938 NADH repair 0.999999999999876 -1.24289467606786e-13 1 0 0 105 902 HUMAN_NADPHOS-DEPHOS-PWY-1 NAD phosphorylation and dephosphorylation 0.999999999999876 -1.24289467606786e-13 1 0 0 105 902 HUMAN_BSUBPOLYAMSYN-PWY spermidine biosynthesis 0.999999999999876 -1.24289467606786e-13 1 0 0 105 902 META_PWY-7501 phosphatidylserine biosynthesis I 0.999999999999876 -1.24289467606786e-13 1 0 0 105 902 META_PWY-6132 lanosterol biosynthesis 0.999999999999876 -1.24289467606786e-13 1 0 0 105 902 META_PWY6666-1 anandamide degradation 0.999999999999876 -1.24289467606786e-13 1 0 0 105 902 META_PWY66-420 carnosine biosynthesis 0.999999999999876 -1.24289467606786e-13 1 0 0 105 902 HUMAN_PWY-46 putrescine biosynthesis I 0.999999999999876 -1.24289467606786e-13 1 0 0 105 902 META_PWY-5652 2-amino-3-carboxymuconate semialdehyde degradation to glutaryl-CoA 0.999999999999876 -1.24289467606786e-13 1 0 0 105 902 HUMAN_MANNCAT-PWY D-mannose degradation 0.999999999999876 -1.24289467606786e-13 1 0 0 105 902 META_PWY66-380 estradiol biosynthesis I (via estrone) 0.999999999999876 -1.24289467606786e-13 1 0 0 105 902 HUMAN_PWY-66 GDP-L-fucose biosynthesis I (from GDP-D-mannose) 0.999999999999876 -1.24289467606786e-13 1 0 0 105 902 META_PWY-5172 acetyl-CoA biosynthesis III (from citrate) 0.999999999999876 -1.24289467606786e-13 1 0 0 105 902 META_PWY-6173 histamine biosynthesis 0.999999999999876 -1.24289467606786e-13 1 0 0 105 902 HUMAN_PWY-7250 [2Fe-2S] iron-sulfur cluster biosynthesis 0.999999999999876 -1.24289467606786e-13 1 0 0 105 902 META_PWY-6481 L-dopachrome biosynthesis 0.999999999999876 -1.24289467606786e-13 1 0 0 105 902 HUMAN_PWY-7501 phosphatidylserine biosynthesis I 0.999999999999876 -1.24289467606786e-13 1 0 0 105 902 HUMAN_PWY-5329 L-cysteine degradation II 0.999999999999876 -1.24289467606786e-13 1 0 0 105 902 HUMAN_GLUT-REDOX-PWY glutathione redox reactions II 0.999999999999876 -1.24289467606786e-13 1 0 0 105 902 HUMAN_PWY-6502 oxidized GTP and dGTP detoxification 0.999999999999876 -1.24289467606786e-13 1 0 0 105 902 META_PWY-5886 4-hydroxyphenylpyruvate biosynthesis 0.999999999999876 -1.24289467606786e-13 1 0 0 105 902 META_PWY0-1313 acetate conversion to acetyl-CoA 0.999999999999876 -1.24289467606786e-13 1 0 0 105 902 HUMAN_PWY-6377 alpha-tocopherol degradation 0.999999999999876 -1.24289467606786e-13 1 0 0 105 902 META_PWY-7725 arachidonate biosynthesis V (8-detaturase, mammals) 0.999999999999876 -1.24289467606786e-13 1 0 0 105 902 META_PWY0-1021 L-alanine biosynthesis III 0.999999999999876 -1.24289467606786e-13 1 0 0 105 902 HUMAN_ALANINE-DEG3-PWY alanine biosynthesis/degradation 0.999999999999876 -1.24289467606786e-13 1 0 0 105 902 HUMAN_SERSYN-PWY serine biosynthesis (phosphorylated route) 0.999999999999876 -1.24289467606786e-13 1 0 0 105 902 META_PWY-6134 L-tyrosine biosynthesis IV 0.999999999999876 -1.24289467606786e-13 1 0 0 105 902 META_NADPHOS-DEPHOS-PWY-1 NAD phosphorylation and transhydrogenation 0.999999999999876 -1.24289467606786e-13 1 0 0 105 902 HUMAN_GLNSYN-PWY glutamine biosynthesis 0.999999999999876 -1.24289467606786e-13 1 0 0 105 902 META_PWY-6307 L-tryptophan degradation X (mammalian, via tryptamine) 0.999999999999876 -1.24289467606786e-13 1 0 0 105 902 META_PWY-5269 cardiolipin biosynthesis II 0.999999999999876 -1.24289467606786e-13 1 0 0 105 902 META_PWY66-388 fatty acid alpha-oxidation III 0.999999999999876 -1.24289467606786e-13 1 0 0 105 902 HUMAN_PWY-5172 acetyl-CoA biosynthesis from citrate 0.999999999999876 -1.24289467606786e-13 1 0 0 105 902 HUMAN_PWY-6481 L-dopachrome biosynthesis 0.999999999999876 -1.24289467606786e-13 1 0 0 105 902 META_PWY-6241 thyroid hormone biosynthesis 0.999999999999876 -1.24289467606786e-13 1 0 0 105 902 META_PWY-4361 S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation 0.999999999999876 -1.24289467606786e-13 1 0 0 105 902 HUMAN_PWY-7306 estradiol biosynthesis II 0.999999999999876 -1.24289467606786e-13 1 0 0 105 902 HUMAN_PWY-6619 adenine and adenosine salvage II 0.999999999999876 -1.24289467606786e-13 1 0 0 105 902 HUMAN_PWY-6334 L-dopa degradation 0.999999999999876 -1.24289467606786e-13 1 0 0 105 902 HUMAN_PWY66-11 BMP Signalling Pathway 0.999999999999876 -1.24289467606786e-13 1 0 0 105 902 META_BSUBPOLYAMSYN-PWY spermidine biosynthesis I 0.999999999999876 -1.24289467606786e-13 1 0 0 105 902 HUMAN_PWY-2161B glutamate removal from folates 0.999999999999876 -1.24289467606786e-13 1 0 0 105 902 META_PWY-6133 (S)-reticuline biosynthesis II 0.999999999999876 -1.24289467606786e-13 1 0 0 105 902 META_PWY-6823 molybdenum cofactor biosynthesis 1.00000000000098 9.76704828126174e-13 4 0 0 105 902 HUMAN_PWY66-380 estradiol biosynthesis I 1.00000000000098 9.76704828126174e-13 4 0 0 105 902 META_PWY-6030 serotonin and melatonin biosynthesis 1.00000000000098 9.76704828126174e-13 4 0 0 105 902 HUMAN_PWY-5046 2-oxoisovalerate decarboxylation to isobutanoyl-CoA 1.00000000000098 9.76704828126174e-13 4 0 0 105 902 HUMAN_HYDROXYPRODEG-PWY 4-hydroxyproline degradation 1.00000000000098 9.76704828126174e-13 4 0 0 105 902 META_PWY-7205 CMP phosphorylation 1.00000000000098 9.76704828126174e-13 4 0 0 105 902 HUMAN_PWY-6117 spermine and spermidine degradation I 1.00000000000098 9.76704828126174e-13 4 0 0 105 902 HUMAN_PWY-4361 S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation 1.00000000000098 9.76704828126174e-13 4 0 0 105 902 HUMAN_PWY-2161 folate polyglutamylation 1.00000000000098 9.76704828126174e-13 4 0 0 105 902 HUMAN_PWY-6875 retinoate biosynthesis II 1.00000000000098 9.76704828126174e-13 4 0 0 105 902 META_PWY-3781 aerobic respiration I (cytochrome c) 1.00000000000098 9.76704828126174e-13 4 0 0 105 902 META_PWY-5046 2-oxoisovalerate decarboxylation to isobutanoyl-CoA 1.00000000000098 9.76704828126174e-13 4 0 0 105 902 META_PYRUVDEHYD-PWY pyruvate decarboxylation to acetyl CoA 1.00000000000098 9.76704828126174e-13 4 0 0 105 902 HUMAN_PWY-5177 glutaryl-CoA degradation 1.00000000000098 9.76704828126174e-13 4 0 0 105 902 HUMAN_PWY-6030 serotonin and melatonin biosynthesis 1.00000000000098 9.76704828126174e-13 4 0 0 105 902 HUMAN_PWY-5659 GDP-mannose biosynthesis 1.00000000000098 9.76704828126174e-13 4 0 0 105 902 META_PWY-6158 creatine-phosphate biosynthesis 1.00000000000098 9.76704828126174e-13 4 0 0 105 902 HUMAN_ASPARAGINE-DEG1-PWY-1 asparagine degradation 1.00000000000098 9.76704828126174e-13 4 0 0 105 902 META_PWY-5067 glycogen biosynthesis II (from UDP-D-Glucose) 1.00000000000098 9.76704828126174e-13 4 0 0 105 902 META_HYDROXYPRODEG-PWY trans-4-hydroxy-L-proline degradation I 1.00000000000098 9.76704828126174e-13 4 0 0 105 902 HUMAN_PWY-6755 S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation 1.00000000000098 9.76704828126174e-13 4 0 0 105 902 META_POLYAMINSYN3-PWY superpathway of polyamine biosynthesis II 1.00000000000098 9.76704828126174e-13 4 0 0 105 902 HUMAN_PWY-4921 protein citrullination 1.00000000000098 9.76704828126174e-13 4 0 0 105 902 HUMAN_SER-GLYSYN-PWY serine and glycine biosynthesis 1.00000000000098 9.76704828126174e-13 4 0 0 105 902 HUMAN_MALATE-ASPARTATE-SHUTTLE-PWY malate-aspartate shuttle 1.00000000000098 9.76704828126174e-13 4 0 0 105 902 HUMAN_PWY-5872 ubiquinol-10 biosynthesis 1.00000000000098 9.76704828126174e-13 4 0 0 105 902 HUMAN_PWY-7112 4-hydroxy-2-nonenal detoxification 1.00000000000098 9.76704828126174e-13 4 0 0 105 902 HUMAN_PWY-6823 molybdenum cofactor biosynthesis 1.00000000000098 9.76704828126174e-13 4 0 0 105 902 META_PWY-5872 ubiquinol-10 biosynthesis (eukaryotic) 1.00000000000098 9.76704828126174e-13 4 0 0 105 902 HUMAN_PWY-6517 N-acetylglucosamine degradation II 1.00000000000098 9.76704828126174e-13 4 0 0 105 902 HUMAN_PWY-4261 glycerol degradation 1.00000000000098 9.76704828126174e-13 4 0 0 105 902 HUMAN_PWY-6261 thyroid hormone metabolism II (via conjugation and/or degradation) 1.00000000000098 9.76704828126174e-13 4 0 0 105 902 META_PWY-7226 guanosine deoxyribonucleotides de novo biosynthesis I 1.00000000000236 2.35995798640934e-12 5 0 0 105 902 META_PWY-7199 pyrimidine deoxyribonucleosides salvage 1.00000000000236 2.35995798640934e-12 5 0 0 105 902 HUMAN_PWY66-375 leukotriene biosynthesis 1.00000000000236 2.35995798640934e-12 5 0 0 105 902 HUMAN_PWY-3661-1 glycine betaine degradation 1.00000000000236 2.35995798640934e-12 5 0 0 105 902 META_CITRULBIO-PWY L-citrulline biosynthesis 1.00000000000236 2.35995798640934e-12 5 0 0 105 902 META_PWY66-375 leukotriene biosynthesis 1.00000000000236 2.35995798640934e-12 5 0 0 105 902 HUMAN_PWY-7180 2'-deoxy-alpha-D-ribose 1-phosphate degradation 1.00000000000236 2.35995798640934e-12 5 0 0 105 902 META_PWY-3661-1 glycine betaine degradation II (mammalian) 1.00000000000236 2.35995798640934e-12 5 0 0 105 902 META_PWY-6111 mitochondrial L-carnitine shuttle 1.00000000000236 2.35995798640934e-12 5 0 0 105 902 META_TYRFUMCAT-PWY L-tyrosine degradation I 1.00000000000236 2.35995798640934e-12 5 0 0 105 902 HUMAN_PWY4FS-6 phosphatidylethanolamine biosynthesis II 1.00000000000236 2.35995798640934e-12 5 0 0 105 902 HUMAN_TYRFUMCAT-PWY tyrosine degradation 1.00000000000236 2.35995798640934e-12 5 0 0 105 902 HUMAN_PYRUVDEHYD-PWY pyruvate decarboxylation to acetyl CoA 1.00000000000236 2.35995798640934e-12 5 0 0 105 902 META_PWY66-378 androgen biosynthesis 1.00000000000236 2.35995798640934e-12 5 0 0 105 902 HUMAN_PWY66-378 androgen biosynthesis 1.00000000000236 2.35995798640934e-12 5 0 0 105 902 META_PWY66-201 nicotine degradation IV 1.00000000000236 2.35995798640934e-12 5 0 0 105 902 META_PWY-4061 glutathione-mediated detoxification I 1.00000000000236 2.35995798640934e-12 5 0 0 105 902 HUMAN_PWY66-422 D-galactose degradation V (Leloir pathway) 1.00000000000236 2.35995798640934e-12 5 0 0 105 902 HUMAN_UDPNACETYLGALSYN-PWY UDP-N-acetyl-D-glucosamine biosynthesis II 1.00000000000236 2.35995798640934e-12 5 0 0 105 902 META_PWY-6261 thyroid hormone metabolism II (via conjugation and/or degradation) 1.00000000000236 2.35995798640934e-12 5 0 0 105 902 META_PWY-7227 adenosine deoxyribonucleotides de novo biosynthesis 1.00000000000236 2.35995798640934e-12 5 0 0 105 902 HUMAN_PWY-7199 pyrimidine deoxyribonucleosides salvage 1.00000000000236 2.35995798640934e-12 5 0 0 105 902 META_PWY-4921 protein citrullination 1.00000000000236 2.35995798640934e-12 5 0 0 105 902 HUMAN_PWY-6111 mitochondrial L-carnitine shuttle 1.00000000000236 2.35995798640934e-12 5 0 0 105 902 META_PWY-7209 superpathway of pyrimidine ribonucleosides degradation 1.00000000000236 2.35995798640934e-12 5 0 0 105 902 META_PWY-7197 pyrimidine deoxyribonucleotide phosphorylation 1.00000000000236 2.35995798640934e-12 5 0 0 105 902 META_PWY-4081 glutathione-peroxide redox reactions 1.00000000000236 2.35995798640934e-12 5 0 0 105 902 META_PWY66-428 L-threonine degradation V 1.00000000000291 2.91457621680311e-12 6 0 0 105 902 META_PWY-7221 guanosine ribonucleotides de novo biosynthesis 1.00000000000291 2.91457621680311e-12 6 0 0 105 902 HUMAN_PWY3O-450 phosphatidylcholine biosynthesis 1.00000000000291 2.91457621680311e-12 6 0 0 105 902 META_PWY-7229 superpathway of adenosine nucleotides de novo biosynthesis I 1.00000000000291 2.91457621680311e-12 6 0 0 105 902 META_ILEUDEG-PWY L-isoleucine degradation I 1.00000000000291 2.91457621680311e-12 6 0 0 105 902 META_PWY-5130 2-oxobutanoate degradation I 1.00000000000291 2.91457621680311e-12 6 0 0 105 902 META_PWY-7176 UTP and CTP de novo biosynthesis 1.00000000000291 2.91457621680311e-12 6 0 0 105 902 HUMAN_PWY-7455 allopregnanolone biosynthesis 1.00000000000291 2.91457621680311e-12 6 0 0 105 902 HUMAN_PENTOSE-P-PWY pentose phosphate pathway 1.00000000000291 2.91457621680311e-12 6 0 0 105 902 META_PWY-7455 allopregnanolone biosynthesis 1.00000000000291 2.91457621680311e-12 6 0 0 105 902 HUMAN_PWY-4081 glutathione redox reactions I 1.00000000000291 2.91457621680311e-12 6 0 0 105 902 HUMAN_PWY-7209 pyrimidine ribonucleosides degradation 1.00000000000291 2.91457621680311e-12 6 0 0 105 902 HUMAN_PWY66-428 threonine degradation 1.00000000000291 2.91457621680311e-12 6 0 0 105 902 HUMAN_PWY-5130 2-oxobutanoate degradation 1.00000000000291 2.91457621680311e-12 6 0 0 105 902 HUMAN_PWY3DJ-11281 sphingomyelin metabolism/ceramide salvage 1.00000000000419 4.18891272792096e-12 7 0 0 105 902 HUMAN_PWY66-374 C20 prostanoid biosynthesis 1.00000000000419 4.18891272792096e-12 7 0 0 105 902 META_PWY-6872 retinoate biosynthesis I 1.00000000000419 4.18891272792096e-12 7 0 0 105 902 META_PWY0-162 superpathway of pyrimidine ribonucleotides de novo biosynthesis 1.00000000000419 4.18891272792096e-12 7 0 0 105 902 META_PWY-7224 purine deoxyribonucleosides salvage 1.00000000000419 4.18891272792096e-12 7 0 0 105 902 META_PWY66-374 C20 prostanoid biosynthesis 1.00000000000419 4.18891272792096e-12 7 0 0 105 902 HUMAN_PWY-6369 inositol pyrophosphates biosynthesis 1.00000000000419 4.18891272792096e-12 7 0 0 105 902 HUMAN_PWY66-414 superpathway of choline degradation to L-serine 1.00000000000419 4.18891272792096e-12 7 0 0 105 902 HUMAN_PWY-5067 glycogen biosynthesis 1.00000000000419 4.18891272792096e-12 7 0 0 105 902 META_PWY-6369 inositol pyrophosphates biosynthesis 1.00000000000419 4.18891272792096e-12 7 0 0 105 902 HUMAN_PWY-5514 UDP-N-acetyl-D-galactosamine biosynthesis II 1.00000000000419 4.18891272792096e-12 7 0 0 105 902 META_DETOX1-PWY-1 reactive oxygen species degradation 1.00000000000419 4.18891272792096e-12 7 0 0 105 902 META_LEU-DEG2-PWY L-leucine degradation I 1.00000000000503 5.03438608085656e-12 8 0 0 105 902 HUMAN_PWY-6872 retinoate biosynthesis I 1.00000000000503 5.03438608085656e-12 8 0 0 105 902 META_PWY-7228 superpathway of guanosine nucleotides de novo biosynthesis I 1.00000000000503 5.03438608085656e-12 8 0 0 105 902 HUMAN_MANNOSYL-CHITO-DOLICHOL-BIOSYNTHESIS dolichyl-diphosphooligosaccharide biosynthesis 1.0000000000062 6.20203896117885e-12 9 0 0 105 902 META_PWY-7210 pyrimidine deoxyribonucleotides biosynthesis from CTP 1.0000000000062 6.20203896117885e-12 9 0 0 105 902 META_PWY-7305 superpathway of steroid hormone biosynthesis 1.0000000000062 6.20203896117885e-12 9 0 0 105 902 META_PWY-6367 D-myo-inositol-5-phosphate metabolism 1.0000000000062 6.20203896117885e-12 9 0 0 105 902 HUMAN_PWY-7527 methionine salvage cycle III 1.0000000000062 6.20203896117885e-12 9 0 0 105 902 META_PWY-7184 pyrimidine deoxyribonucleotides de novo biosynthesis I 1.0000000000062 6.20203896117885e-12 9 0 0 105 902 HUMAN_DETOX1-PWY-1 reactive oxygen species degradation 1.00000000000765 7.64620128098911e-12 10 0 0 105 902 HUMAN_PWY-7227 adenosine deoxyribonucleotides de novo biosynthesis 1.00000000000765 7.64620128098911e-12 10 0 0 105 902 META_PWY-7200 superpathway of pyrimidine deoxyribonucleoside salvage 1.00000000000765 7.64620128098911e-12 10 0 0 105 902 HUMAN_PWY-7226 guanosine deoxyribonucleotides de novo biosynthesis 1.00000000000765 7.64620128098911e-12 10 0 0 105 902 HUMAN_PWY-7221 guanosine ribonucleotides de novo biosynthesis 1.00000000000788 7.87657544084049e-12 11 0 0 105 902 HUMAN_PWY-7224 purine deoxyribonucleosides salvage 1.00000000000788 7.87657544084049e-12 11 0 0 105 902 HUMAN_PWY-7305 superpathway of steroid hormone biosynthesis 1.00000000001013 1.01295105124335e-11 12 0 0 105 902 HUMAN_LEU-DEG2-PWY leucine degradation 1.00000000001013 1.01295105124335e-11 12 0 0 105 902 HUMAN_ILEUDEG-PWY isoleucine degradation 1.00000000001013 1.01295105124335e-11 12 0 0 105 902 META_PWY-7211 superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis 1.0000000000119 1.18955525929063e-11 13 0 0 105 902 META_PWY-6351 D-myo-inositol (1,4,5)-trisphosphate biosynthesis 1.0000000000119 1.18955525929063e-11 13 0 0 105 902 META_PWY-841 superpathway of purine nucleotides de novo biosynthesis I 1.0000000000119 1.18955525929063e-11 13 0 0 105 902 HUMAN_PWY-7184 pyrimidine deoxyribonucleotides de novo biosynthesis 1.00000000001262 1.26247952664332e-11 14 0 0 105 902 HUMAN_PWY-7228 guanosine nucleotides de novo biosynthesis 1.00000000001262 1.26247952664332e-11 14 0 0 105 902 HUMAN_PWY-7210 pyrimidine deoxyribonucleotides biosynthesis from CTP 1.00000000001262 1.26247952664332e-11 14 0 0 105 902 META_PWY66-398 TCA cycle III (animals) 1.00000000001512 1.51155286313553e-11 16 0 0 105 902 HUMAN_PWY66-398 TCA cycle 1.00000000001512 1.51155286313553e-11 16 0 0 105 902 HUMAN_PWY-6367 D-myo-inositol-5-phosphate metabolism 1.00000000001649 1.64911860569961e-11 17 0 0 105 902 HUMAN_PWY-7511 protein ubiquitylation 1.00000000002832 2.83219718814681e-11 29 0 0 105 902