TermID	Term	Enrichment	logP	Genes in Term	Target Genes in Term	Fraction of Targets in Term	Total Target Genes	Total Genes	Entrez Gene IDs	Gene Symbols
hsa04360	Axon guidance	2.36450680382416e-05	-10.652356004383	174	36	0.0493150684931507	730	7161	2042,1948,10501,659,6092,57144,29984,5362,55740,2047,5578,57556,5881,3983,10505,57522,7220,2051,4233,22854,9353,10500,2242,56896,5058,54961,8633,5163,1630,1944,2770,10512,219699,8829,7222,10371	EPHA3,EFNB2,SEMA6B,BMPR2,ROBO2,PAK5,RHOD,PLXNA2,ENAH,EPHB1,PRKCA,SEMA6A,RAC3,ABLIM1,SEMA4F,SRGAP1,TRPC1,EPHB6,MET,NTNG1,SLIT2,SEMA6C,FES,DPYSL5,PAK1,SSH3,UNC5C,PDK1,DCC,EFNA3,GNAI1,SEMA3C,UNC5B,NRP1,TRPC3,SEMA3A
ko04360	Axon guidance	2.36450680382416e-05	-10.652356004383	174	36	0.0493150684931507	730	7161	2042,1948,10501,659,6092,57144,29984,5362,55740,2047,5578,57556,5881,3983,10505,57522,7220,2051,4233,22854,9353,10500,2242,56896,5058,54961,8633,5163,1630,1944,2770,10512,219699,8829,7222,10371	EPHA3,EFNB2,SEMA6B,BMPR2,ROBO2,PAK5,RHOD,PLXNA2,ENAH,EPHB1,PRKCA,SEMA6A,RAC3,ABLIM1,SEMA4F,SRGAP1,TRPC1,EPHB6,MET,NTNG1,SLIT2,SEMA6C,FES,DPYSL5,PAK1,SSH3,UNC5C,PDK1,DCC,EFNA3,GNAI1,SEMA3C,UNC5B,NRP1,TRPC3,SEMA3A
hsa04911	Insulin secretion	8.79401727726822e-05	-9.33885382954806	85	21	0.0287671232876712	730	7161	64764,54795,468,11069,107,6262,9586,6616,481,5578,23236,27445,27345,3781,5579,27094,112,5567,1131,9699,478	CREB3L2,TRPM4,ATF4,RAPGEF4,ADCY1,RYR2,CREB5,SNAP25,ATP1B1,PRKCA,PLCB1,PCLO,KCNMB4,KCNN2,PRKCB,KCNMB3,ADCY6,PRKACB,CHRM3,RIMS2,ATP1A3
ko04666	Fc gamma R-mediated phagocytosis	0.000210224879492766	-8.46733274547527	90	21	0.0287671232876712	730	7161	5058,5321,10451,10810,3636,4651,55616,8612,5578,1794,85477,5788,8611,2934,5579,10000,5580,4082,5337,6850,9846	PAK1,PLA2G4A,VAV3,WASF3,INPPL1,MYO10,ASAP3,PLPP2,PRKCA,DOCK2,SCIN,PTPRC,PLPP1,GSN,PRKCB,AKT3,PRKCD,MARCKS,PLD1,SYK,GAB2
hsa04666	Fc gamma R-mediated phagocytosis	0.000210224879492766	-8.46733274547527	90	21	0.0287671232876712	730	7161	5058,5321,10451,10810,3636,4651,55616,8612,5578,1794,85477,5788,8611,2934,5579,10000,5580,4082,5337,6850,9846	PAK1,PLA2G4A,VAV3,WASF3,INPPL1,MYO10,ASAP3,PLPP2,PRKCA,DOCK2,SCIN,PTPRC,PLPP1,GSN,PRKCB,AKT3,PRKCD,MARCKS,PLD1,SYK,GAB2
hsa04550	Signaling pathways regulating pluripotency of stem cells	0.000300381659591657	-8.11045669322821	139	28	0.0383561643835616	730	7161	2264,90,3397,4093,659,8322,130399,8325,5013,1852,7481,93,2260,4088,3626,3399,3480,5462,4609,10000,7703,83729,92,5603,652,657,3977,8321	FGFR4,ACVR1,ID1,SMAD9,BMPR2,FZD4,ACVR1C,FZD8,OTX1,DUSP9,WNT11,ACVR2B,FGFR1,SMAD3,INHBC,ID3,IGF1R,POU5F1B,MYC,AKT3,PCGF2,INHBE,ACVR2A,MAPK13,BMP4,BMPR1A,LIFR,FZD1
ko04550	Signaling pathways regulating pluripotency of stem cells	0.000300381659591657	-8.11045669322821	139	28	0.0383561643835616	730	7161	2264,90,3397,4093,659,8322,130399,8325,5013,1852,7481,93,2260,4088,3626,3399,3480,5462,4609,10000,7703,83729,92,5603,652,657,3977,8321	FGFR4,ACVR1,ID1,SMAD9,BMPR2,FZD4,ACVR1C,FZD8,OTX1,DUSP9,WNT11,ACVR2B,FGFR1,SMAD3,INHBC,ID3,IGF1R,POU5F1B,MYC,AKT3,PCGF2,INHBE,ACVR2A,MAPK13,BMP4,BMPR1A,LIFR,FZD1
hsa_M00679	BMP signaling	0.00046286947346994	-7.67806545837522	20	8	0.010958904109589	730	7161	90,4093,659,92,652,657,93,654	ACVR1,SMAD9,BMPR2,ACVR2A,BMP4,BMPR1A,ACVR2B,BMP6
M00679	BMP signaling	0.00046286947346994	-7.67806545837522	20	8	0.010958904109589	730	7161	90,4093,659,92,652,657,93,654	ACVR1,SMAD9,BMPR2,ACVR2A,BMP4,BMPR1A,ACVR2B,BMP6
hsa04015	Rap1 signaling pathway	0.000586771166003108	-7.44087565059342	210	37	0.0506849315068493	730	7161	9170,3397,2258,5028,3937,5578,5217,5881,57568,3480,3690,112,4233,83660,9771,5159,7424,2264,9693,11069,107,1944,2257,8822,8631,23236,260425,2260,2770,5579,5608,10000,2775,1435,5603,3082,9863	LPAR2,ID1,FGF13,P2RY1,LCP2,PRKCA,PFN2,RAC3,SIPA1L2,IGF1R,ITGB3,ADCY6,MET,TLN2,RAPGEF5,PDGFRB,VEGFC,FGFR4,RAPGEF2,RAPGEF4,ADCY1,EFNA3,FGF12,FGF17,SKAP1,PLCB1,MAGI3,FGFR1,GNAI1,PRKCB,MAP2K6,AKT3,GNAO1,CSF1,MAPK13,HGF,MAGI2
ko04015	Rap1 signaling pathway	0.000586771166003108	-7.44087565059342	210	37	0.0506849315068493	730	7161	9170,3397,2258,5028,3937,5578,5217,5881,57568,3480,3690,112,4233,83660,9771,5159,7424,2264,9693,11069,107,1944,2257,8822,8631,23236,260425,2260,2770,5579,5608,10000,2775,1435,5603,3082,9863	LPAR2,ID1,FGF13,P2RY1,LCP2,PRKCA,PFN2,RAC3,SIPA1L2,IGF1R,ITGB3,ADCY6,MET,TLN2,RAPGEF5,PDGFRB,VEGFC,FGFR4,RAPGEF2,RAPGEF4,ADCY1,EFNA3,FGF12,FGF17,SKAP1,PLCB1,MAGI3,FGFR1,GNAI1,PRKCB,MAP2K6,AKT3,GNAO1,CSF1,MAPK13,HGF,MAGI2
ko04724	Glutamatergic synapse	0.000990513022790123	-6.91728754421889	114	23	0.0315068493150685	730	7161	5321,9229,55970,2898,9455,22941,107,6507,3709,5578,23236,157,9454,2770,2900,5579,2775,59345,112,7220,2906,5337,5567	PLA2G4A,DLGAP1,GNG12,GRIK2,HOMER2,SHANK2,ADCY1,SLC1A3,ITPR2,PRKCA,PLCB1,GRK3,HOMER3,GNAI1,GRIK4,PRKCB,GNAO1,GNB4,ADCY6,TRPC1,GRIN2D,PLD1,PRKACB
hsa04724	Glutamatergic synapse	0.000990513022790123	-6.91728754421889	114	23	0.0315068493150685	730	7161	5321,9229,55970,2898,9455,22941,107,6507,3709,5578,23236,157,9454,2770,2900,5579,2775,59345,112,7220,2906,5337,5567	PLA2G4A,DLGAP1,GNG12,GRIK2,HOMER2,SHANK2,ADCY1,SLC1A3,ITPR2,PRKCA,PLCB1,GRK3,HOMER3,GNAI1,GRIK4,PRKCB,GNAO1,GNB4,ADCY6,TRPC1,GRIN2D,PLD1,PRKACB
hsa04151	PI3K-Akt signaling pathway	0.00103161768683656	-6.87662713905117	341	53	0.0726027397260274	730	7161	64764,5563,1299,55970,9170,2335,2258,3655,10319,1147,1287,9586,5585,5578,5523,54541,3480,118788,4609,2690,3690,23678,6446,5521,4233,5106,7099,1298,6850,5159,4846,2264,7424,3695,1292,468,1285,3164,1286,2257,1944,8822,10110,2260,29941,1435,7060,1978,10000,59345,3673,3912,3082	CREB3L2,PRKAA2,COL9A3,GNG12,LPAR2,FN1,FGF13,ITGA6,LAMC3,CHUK,COL4A5,CREB5,PKN1,PRKCA,PPP2R3A,DDIT4,IGF1R,PIK3AP1,MYC,GHR,ITGB3,SGK3,SGK1,PPP2R2B,MET,PCK2,TLR4,COL9A2,SYK,PDGFRB,NOS3,FGFR4,VEGFC,ITGB7,COL6A2,ATF4,COL4A3,NR4A1,COL4A4,FGF12,EFNA3,FGF17,SGK2,FGFR1,PKN3,CSF1,THBS4,EIF4EBP1,AKT3,GNB4,ITGA2,LAMB1,HGF
ko04151	PI3K-Akt signaling pathway	0.00103161768683656	-6.87662713905117	341	53	0.0726027397260274	730	7161	64764,5563,1299,55970,9170,2335,2258,3655,10319,1147,1287,9586,5585,5578,5523,54541,3480,118788,4609,2690,3690,23678,6446,5521,4233,5106,7099,1298,6850,5159,4846,2264,7424,3695,1292,468,1285,3164,1286,2257,1944,8822,10110,2260,29941,1435,7060,1978,10000,59345,3673,3912,3082	CREB3L2,PRKAA2,COL9A3,GNG12,LPAR2,FN1,FGF13,ITGA6,LAMC3,CHUK,COL4A5,CREB5,PKN1,PRKCA,PPP2R3A,DDIT4,IGF1R,PIK3AP1,MYC,GHR,ITGB3,SGK3,SGK1,PPP2R2B,MET,PCK2,TLR4,COL9A2,SYK,PDGFRB,NOS3,FGFR4,VEGFC,ITGB7,COL6A2,ATF4,COL4A3,NR4A1,COL4A4,FGF12,EFNA3,FGF17,SGK2,FGFR1,PKN3,CSF1,THBS4,EIF4EBP1,AKT3,GNB4,ITGA2,LAMB1,HGF
hsa04010	MAPK signaling pathway	0.00107574629460706	-6.83474063072553	255	42	0.0575342465753425	730	7161	5321,55970,10368,2258,1850,1147,5578,785,5881,2122,6196,4609,783,22800,3306,5159,5567,10125,1843,5058,2264,627,468,3164,9693,777,2257,1852,8822,2260,9261,5579,5608,5924,10000,7132,5603,5602,51776,781,1649,4208	PLA2G4A,GNG12,CACNG3,FGF13,DUSP8,CHUK,PRKCA,CACNB4,RAC3,MECOM,RPS6KA2,MYC,CACNB2,RRAS2,HSPA2,PDGFRB,PRKACB,RASGRP1,DUSP1,PAK1,FGFR4,BDNF,ATF4,NR4A1,RAPGEF2,CACNA1E,FGF12,DUSP9,FGF17,FGFR1,MAPKAPK2,PRKCB,MAP2K6,RASGRF2,AKT3,TNFRSF1A,MAPK13,MAPK10,MAP3K20,CACNA2D1,DDIT3,MEF2C
ko04010	MAPK signaling pathway	0.00107574629460706	-6.83474063072553	255	42	0.0575342465753425	730	7161	5321,55970,10368,1850,2258,1147,5578,785,5881,2122,6196,783,4609,22800,3306,5567,10125,5159,1843,5058,2264,627,468,777,3164,9693,2257,1852,8822,2260,9261,5579,5608,10000,5924,7132,5603,5602,51776,781,1649,4208	PLA2G4A,GNG12,CACNG3,DUSP8,FGF13,CHUK,PRKCA,CACNB4,RAC3,MECOM,RPS6KA2,CACNB2,MYC,RRAS2,HSPA2,PRKACB,RASGRP1,PDGFRB,DUSP1,PAK1,FGFR4,BDNF,ATF4,CACNA1E,NR4A1,RAPGEF2,FGF12,DUSP9,FGF17,FGFR1,MAPKAPK2,PRKCB,MAP2K6,AKT3,RASGRF2,TNFRSF1A,MAPK13,MAPK10,MAP3K20,CACNA2D1,DDIT3,MEF2C
ko04261	Adrenergic signaling in cardiomyocytes	0.00122010619730258	-6.70881737705601	144	27	0.036986301369863	730	7161	64764,6331,468,10368,11069,107,6262,9586,481,5578,785,23236,5523,2770,6324,10000,783,153,112,5603,5521,7168,5567,493,490,781,478	CREB3L2,SCN5A,ATF4,CACNG3,RAPGEF4,ADCY1,RYR2,CREB5,ATP1B1,PRKCA,CACNB4,PLCB1,PPP2R3A,GNAI1,SCN1B,AKT3,CACNB2,ADRB1,ADCY6,MAPK13,PPP2R2B,TPM1,PRKACB,ATP2B4,ATP2B1,CACNA2D1,ATP1A3
hsa04261	Adrenergic signaling in cardiomyocytes	0.00122010619730258	-6.70881737705601	144	27	0.036986301369863	730	7161	64764,6331,468,10368,11069,107,6262,9586,481,5578,785,23236,5523,2770,6324,10000,783,153,112,5603,5521,7168,5567,493,490,781,478	CREB3L2,SCN5A,ATF4,CACNG3,RAPGEF4,ADCY1,RYR2,CREB5,ATP1B1,PRKCA,CACNB4,PLCB1,PPP2R3A,GNAI1,SCN1B,AKT3,CACNB2,ADRB1,ADCY6,MAPK13,PPP2R2B,TPM1,PRKACB,ATP2B4,ATP2B1,CACNA2D1,ATP1A3
ko04350	TGF-beta signaling pathway	0.00168097332605094	-6.388382292587	84	18	0.0246575342465753	730	7161	4681,3397,90,659,4093,130399,93,654,9372,4088,3399,3626,4609,83729,92,657,652,4091	NBL1,ID1,ACVR1,BMPR2,SMAD9,ACVR1C,ACVR2B,BMP6,ZFYVE9,SMAD3,ID3,INHBC,MYC,INHBE,ACVR2A,BMPR1A,BMP4,SMAD6
hsa04350	TGF-beta signaling pathway	0.00168097332605094	-6.388382292587	84	18	0.0246575342465753	730	7161	4681,3397,90,659,4093,130399,93,654,9372,4088,3399,3626,4609,83729,92,657,652,4091	NBL1,ID1,ACVR1,BMPR2,SMAD9,ACVR1C,ACVR2B,BMP6,ZFYVE9,SMAD3,ID3,INHBC,MYC,INHBE,ACVR2A,BMPR1A,BMP4,SMAD6
hsa04392	Hippo signaling pathway -multiple species	0.00173146454098992	-6.35878767311294	29	9	0.0123287671232877	730	7161	92597,5058,26524,79633,25937,8642,23286,10413,60485	MOB1B,PAK1,LATS2,FAT4,WWTR1,DCHS1,WWC1,YAP1,SAV1
ko04392	Hippo signaling pathway -multiple species	0.00173146454098992	-6.35878767311294	29	9	0.0123287671232877	730	7161	92597,5058,26524,79633,25937,8642,23286,10413,60485	MOB1B,PAK1,LATS2,FAT4,WWTR1,DCHS1,WWC1,YAP1,SAV1
hsa_M00681	Activin signaling	0.00176718312467326	-6.33836845509293	10	5	0.00684931506849315	730	7161	4088,92,3626,93,83729	SMAD3,ACVR2A,INHBC,ACVR2B,INHBE
hsa_M00095	C5 isoprenoid biosynthesis, mevalonate pathway	0.00176718312467326	-6.33836845509293	10	5	0.00684931506849315	730	7161	4598,3422,3157,4597,3156	MVK,IDI1,HMGCS1,MVD,HMGCR
M00681	Activin signaling	0.00176718312467326	-6.33836845509293	10	5	0.00684931506849315	730	7161	4088,92,3626,93,83729	SMAD3,ACVR2A,INHBC,ACVR2B,INHBE
M00095	C5 isoprenoid biosynthesis, mevalonate pathway	0.00176718312467326	-6.33836845509293	10	5	0.00684931506849315	730	7161	4598,3422,3157,4597,3156	MVK,IDI1,HMGCS1,MVD,HMGCR
hsa04152	AMPK signaling pathway	0.00203072576680918	-6.19936202922805	120	23	0.0315068493150685	730	7161	64764,5210,5563,23216,5208,2194,55437,6319,9586,3953,5523,8660,3480,1938,10000,1978,8900,6720,81617,5521,5106,10891,3156	CREB3L2,PFKFB4,PRKAA2,TBC1D1,PFKFB2,FASN,STRADB,SCD,CREB5,LEPR,PPP2R3A,IRS2,IGF1R,EEF2,AKT3,EIF4EBP1,CCNA1,SREBF1,CAB39L,PPP2R2B,PCK2,PPARGC1A,HMGCR
ko04152	AMPK signaling pathway	0.00203072576680918	-6.19936202922805	120	23	0.0315068493150685	730	7161	64764,5210,5563,23216,5208,2194,55437,6319,9586,3953,5523,8660,3480,1938,10000,1978,8900,6720,81617,5521,5106,10891,3156	CREB3L2,PFKFB4,PRKAA2,TBC1D1,PFKFB2,FASN,STRADB,SCD,CREB5,LEPR,PPP2R3A,IRS2,IGF1R,EEF2,AKT3,EIF4EBP1,CCNA1,SREBF1,CAB39L,PPP2R2B,PCK2,PPARGC1A,HMGCR
hsa04974	Protein digestion and absorption	0.00329728544932053	-5.71465574013842	89	18	0.0246575342465753	730	7161	1299,6520,1292,1285,206358,1286,80781,1287,481,7373,85301,169044,5547,6510,1298,117247,4311,478	COL9A3,SLC3A2,COL6A2,COL4A3,SLC36A1,COL4A4,COL18A1,COL4A5,ATP1B1,COL14A1,COL27A1,COL22A1,PRCP,SLC1A5,COL9A2,SLC16A10,MME,ATP1A3
ko04974	Protein digestion and absorption	0.00329728544932053	-5.71465574013842	89	18	0.0246575342465753	730	7161	1299,6520,1292,1285,206358,1286,80781,1287,481,7373,85301,169044,5547,6510,1298,117247,4311,478	COL9A3,SLC3A2,COL6A2,COL4A3,SLC36A1,COL4A4,COL18A1,COL4A5,ATP1B1,COL14A1,COL27A1,COL22A1,PRCP,SLC1A5,COL9A2,SLC16A10,MME,ATP1A3
M00683	Hippo signaling	0.00359078428852812	-5.62938463557084	16	6	0.00821917808219178	730	7161	23286,92597,10413,26524,60485,25937	WWC1,MOB1B,YAP1,LATS2,SAV1,WWTR1
hsa_M00683	Hippo signaling	0.00359078428852812	-5.62938463557084	16	6	0.00821917808219178	730	7161	23286,92597,10413,26524,60485,25937	WWC1,MOB1B,YAP1,LATS2,SAV1,WWTR1
hsa05032	Morphine addiction	0.00423222063418287	-5.46502845105381	91	18	0.0246575342465753	730	7161	55970,5153,2561,107,2566,5151,2570,2870,5578,157,2770,5579,2775,59345,10846,112,5144,5567	GNG12,PDE1B,GABRB2,ADCY1,GABRG2,PDE8A,GABRR2,GRK6,PRKCA,GRK3,GNAI1,PRKCB,GNAO1,GNB4,PDE10A,ADCY6,PDE4D,PRKACB
ko05032	Morphine addiction	0.00423222063418287	-5.46502845105381	91	18	0.0246575342465753	730	7161	55970,5153,2561,107,2566,5151,2570,2870,5578,157,2770,5579,2775,59345,10846,112,5144,5567	GNG12,PDE1B,GABRB2,ADCY1,GABRG2,PDE8A,GABRR2,GRK6,PRKCA,GRK3,GNAI1,PRKCB,GNAO1,GNB4,PDE10A,ADCY6,PDE4D,PRKACB
M00056	O-glycan biosynthesis, mucin type core	0.00427998434963135	-5.45380592602331	27	8	0.010958904109589	730	7161	2591,2589,11226,79695,114805,64409,79623,374378	GALNT3,GALNT1,GALNT6,GALNT12,GALNT13,GALNT17,GALNT14,GALNT18
hsa_M00056	O-glycan biosynthesis, mucin type core	0.00427998434963135	-5.45380592602331	27	8	0.010958904109589	730	7161	2591,2589,11226,79695,114805,64409,79623,374378	GALNT3,GALNT1,GALNT6,GALNT12,GALNT13,GALNT17,GALNT14,GALNT18
ko05418	Fluid shear stress and atherosclerosis	0.00439154192894735	-5.42807487690195	142	25	0.0342465753424658	730	7161	5563,90,2946,659,4259,2948,445,1147,9446,93,5881,119391,5608,10000,3690,7132,2947,92,5603,657,652,5602,4846,1843,4208	PRKAA2,ACVR1,GSTM2,BMPR2,MGST3,GSTM4,ASS1,CHUK,GSTO1,ACVR2B,RAC3,GSTO2,MAP2K6,AKT3,ITGB3,TNFRSF1A,GSTM3,ACVR2A,MAPK13,BMPR1A,BMP4,MAPK10,NOS3,DUSP1,MEF2C
hsa05418	Fluid shear stress and atherosclerosis	0.00439154192894735	-5.42807487690195	142	25	0.0342465753424658	730	7161	5563,90,2946,659,4259,2948,445,1147,9446,93,5881,119391,5608,10000,3690,7132,2947,92,5603,657,652,5602,4846,1843,4208	PRKAA2,ACVR1,GSTM2,BMPR2,MGST3,GSTM4,ASS1,CHUK,GSTO1,ACVR2B,RAC3,GSTO2,MAP2K6,AKT3,ITGB3,TNFRSF1A,GSTM3,ACVR2A,MAPK13,BMPR1A,BMP4,MAPK10,NOS3,DUSP1,MEF2C
hsa04150	mTOR signaling pathway	0.00460841579357355	-5.37987112667893	150	26	0.0356164383561644	730	7161	5563,6520,83667,8322,8325,64798,55437,90423,1147,7481,5578,54541,6196,3480,5579,1978,10000,8140,7132,6446,4040,81617,2887,58528,8321,220441	PRKAA2,SLC3A2,SESN2,FZD4,FZD8,DEPTOR,STRADB,ATP6V1E2,CHUK,WNT11,PRKCA,DDIT4,RPS6KA2,IGF1R,PRKCB,EIF4EBP1,AKT3,SLC7A5,TNFRSF1A,SGK1,LRP6,CAB39L,GRB10,RRAGD,FZD1,RNF152
ko04150	mTOR signaling pathway	0.00460841579357355	-5.37987112667893	150	26	0.0356164383561644	730	7161	5563,6520,83667,8322,8325,64798,55437,90423,1147,7481,5578,54541,6196,3480,5579,1978,10000,8140,7132,6446,4040,81617,2887,58528,8321,220441	PRKAA2,SLC3A2,SESN2,FZD4,FZD8,DEPTOR,STRADB,ATP6V1E2,CHUK,WNT11,PRKCA,DDIT4,RPS6KA2,IGF1R,PRKCB,EIF4EBP1,AKT3,SLC7A5,TNFRSF1A,SGK1,LRP6,CAB39L,GRB10,RRAGD,FZD1,RNF152
hsa_M00003	Gluconeogenesis, oxaloacetate => fructose-6P	0.00507782444439942	-5.2828723680973	17	6	0.00821917808219178	730	7161	2597,5106,2026,2023,230,226	GAPDH,PCK2,ENO2,ENO1,ALDOC,ALDOA
M00003	Gluconeogenesis, oxaloacetate => fructose-6P	0.00507782444439942	-5.2828723680973	17	6	0.00821917808219178	730	7161	2597,5106,2026,2023,230,226	GAPDH,PCK2,ENO2,ENO1,ALDOC,ALDOA
hsa05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	0.00525244460496123	-5.24906167171459	72	15	0.0205479452054795	730	7161	83439,3695,10368,783,3655,1829,3673,3690,6262,5318,1000,1832,785,781,1496	TCF7L1,ITGB7,CACNG3,CACNB2,ITGA6,DSG2,ITGA2,ITGB3,RYR2,PKP2,CDH2,DSP,CACNB4,CACNA2D1,CTNNA2
ko04520	Adherens junction	0.00525244460496123	-5.24906167171459	72	15	0.0205479452054795	730	7161	4088,2241,83439,10810,5795,10580,3480,5777,7082,4233,5881,6591,2260,10458,1496	SMAD3,FER,TCF7L1,WASF3,PTPRJ,SORBS1,IGF1R,PTPN6,TJP1,MET,RAC3,SNAI2,FGFR1,BAIAP2,CTNNA2
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	0.00525244460496123	-5.24906167171459	72	15	0.0205479452054795	730	7161	83439,3695,10368,783,3655,1829,3673,3690,6262,5318,1000,1832,785,781,1496	TCF7L1,ITGB7,CACNG3,CACNB2,ITGA6,DSG2,ITGA2,ITGB3,RYR2,PKP2,CDH2,DSP,CACNB4,CACNA2D1,CTNNA2
hsa04520	Adherens junction	0.00525244460496123	-5.24906167171459	72	15	0.0205479452054795	730	7161	4088,2241,83439,10810,5795,10580,3480,5777,7082,4233,5881,6591,2260,10458,1496	SMAD3,FER,TCF7L1,WASF3,PTPRJ,SORBS1,IGF1R,PTPN6,TJP1,MET,RAC3,SNAI2,FGFR1,BAIAP2,CTNNA2
hsa04611	Platelet activation	0.00601475228195496	-5.11354011378594	123	22	0.0301369863013699	730	7161	5321,91807,8673,107,5028,3709,2977,3937,23236,2770,10000,3690,3673,5592,112,5593,5603,83660,6850,5567,10125,4846	PLA2G4A,MYLK3,VAMP8,ADCY1,P2RY1,ITPR2,GUCY1A2,LCP2,PLCB1,GNAI1,AKT3,ITGB3,ITGA2,PRKG1,ADCY6,PRKG2,MAPK13,TLN2,SYK,PRKACB,RASGRP1,NOS3
hsa01230	Biosynthesis of amino acids	0.00684538401449833	-4.98418072035468	74	15	0.0205479452054795	730	7161	84706,2597,2026,51166,230,226,48,445,875,100526760,26227,2023,5723,1491,5831	GPT2,GAPDH,ENO2,AADAT,ALDOC,ALDOA,ACO1,ASS1,CBS,ABHD14A-ACY1,PHGDH,ENO1,PSPH,CTH,PYCR1
ko01230	Biosynthesis of amino acids	0.00684538401449833	-4.98418072035468	74	15	0.0205479452054795	730	7161	84706,2597,2026,51166,230,226,48,445,875,100526760,26227,2023,5723,1491,5831	GPT2,GAPDH,ENO2,AADAT,ALDOC,ALDOA,ACO1,ASS1,CBS,ABHD14A-ACY1,PHGDH,ENO1,PSPH,CTH,PYCR1
hsa04510	Focal adhesion	0.00975722855959506	-4.62974687793903	198	31	0.0424657534246575	730	7161	5058,7424,1299,3695,10451,5829,1292,91807,2335,1285,57144,1793,1286,3655,10319,1287,5578,5881,3480,5579,7060,10000,3673,3912,3690,3082,4233,83660,5602,1298,5159	PAK1,VEGFC,COL9A3,ITGB7,VAV3,PXN,COL6A2,MYLK3,FN1,COL4A3,PAK5,DOCK1,COL4A4,ITGA6,LAMC3,COL4A5,PRKCA,RAC3,IGF1R,PRKCB,THBS4,AKT3,ITGA2,LAMB1,ITGB3,HGF,MET,TLN2,MAPK10,COL9A2,PDGFRB
ko04510	Focal adhesion	0.00975722855959506	-4.62974687793903	198	31	0.0424657534246575	730	7161	5058,7424,1299,3695,10451,5829,1292,91807,2335,1285,57144,1793,1286,3655,10319,1287,5578,5881,3480,5579,7060,10000,3673,3912,3690,3082,4233,83660,5602,1298,5159	PAK1,VEGFC,COL9A3,ITGB7,VAV3,PXN,COL6A2,MYLK3,FN1,COL4A3,PAK5,DOCK1,COL4A4,ITGA6,LAMC3,COL4A5,PRKCA,RAC3,IGF1R,PRKCB,THBS4,AKT3,ITGA2,LAMB1,ITGB3,HGF,MET,TLN2,MAPK10,COL9A2,PDGFRB
hsa_M00001	Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate	0.0103603124631585	-4.56977288206908	25	7	0.00958904109589041	730	7161	3098,2597,2026,2023,230,226,3099	HK1,GAPDH,ENO2,ENO1,ALDOC,ALDOA,HK2
M00001	Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate	0.0103603124631585	-4.56977288206908	25	7	0.00958904109589041	730	7161	3098,2597,2026,2023,230,226,3099	HK1,GAPDH,ENO2,ENO1,ALDOC,ALDOA,HK2
M00338	Cysteine biosynthesis, homocysteine + serine => cysteine	0.0103791955025256	-4.56795190882167	2	2	0.00273972602739726	730	7161	875,1491	CBS,CTH
hsa_M00338	Cysteine biosynthesis, homocysteine + serine => cysteine	0.0103791955025256	-4.56795190882167	2	2	0.00273972602739726	730	7161	875,1491	CBS,CTH
ko00512	Mucin type O-glycan biosynthesis	0.0105540871118869	-4.55124209011129	31	8	0.010958904109589	730	7161	2591,64409,2589,114805,79623,374378,11226,79695	GALNT3,GALNT17,GALNT1,GALNT13,GALNT14,GALNT18,GALNT6,GALNT12
hsa00512	Mucin type O-glycan biosynthesis	0.0105540871118869	-4.55124209011129	31	8	0.010958904109589	730	7161	2591,2589,11226,79695,114805,64409,374378,79623	GALNT3,GALNT1,GALNT6,GALNT12,GALNT13,GALNT17,GALNT18,GALNT14
hsa04931	Insulin resistance	0.0110672925177481	-4.50376114051829	107	19	0.026027397260274	730	7161	64764,5563,5509,11001,5588,9586,8660,57761,6196,5579,10000,5580,6720,7132,10891,5106,5602,9882,4846	CREB3L2,PRKAA2,PPP1R3D,SLC27A2,PRKCQ,CREB5,IRS2,TRIB3,RPS6KA2,PRKCB,AKT3,PRKCD,SREBF1,TNFRSF1A,PPARGC1A,PCK2,MAPK10,TBC1D4,NOS3
hsa00100	Steroid biosynthesis	0.0121993596327945	-4.40637181773573	20	6	0.00821917808219178	730	7161	1595,6713,8435,1717,6307,1718	CYP51A1,SQLE,SOAT2,DHCR7,MSMO1,DHCR24
ko00100	Steroid biosynthesis	0.0121993596327945	-4.40637181773573	20	6	0.00821917808219178	730	7161	6713,1595,8435,1717,6307,1718	SQLE,CYP51A1,SOAT2,DHCR7,MSMO1,DHCR24
hsa04390	Hippo signaling pathway	0.012397939919182	-4.39022495572303	154	25	0.0342465753424658	730	7161	92597,26524,3397,659,8322,8325,23286,10413,7481,60485,654,1496,10207,4088,83439,4609,25937,27113,1740,652,5521,657,8945,6591,8321	MOB1B,LATS2,ID1,BMPR2,FZD4,FZD8,WWC1,YAP1,WNT11,SAV1,BMP6,CTNNA2,PATJ,SMAD3,TCF7L1,MYC,WWTR1,BBC3,DLG2,BMP4,PPP2R2B,BMPR1A,BTRC,SNAI2,FZD1
ko04390	Hippo signaling pathway	0.012397939919182	-4.39022495572303	154	25	0.0342465753424658	730	7161	92597,26524,3397,659,8322,8325,23286,10413,7481,60485,654,1496,10207,4088,83439,4609,25937,27113,1740,652,5521,657,8945,6591,8321	MOB1B,LATS2,ID1,BMPR2,FZD4,FZD8,WWC1,YAP1,WNT11,SAV1,BMP6,CTNNA2,PATJ,SMAD3,TCF7L1,MYC,WWTR1,BBC3,DLG2,BMP4,PPP2R2B,BMPR1A,BTRC,SNAI2,FZD1
hsa04014	Ras signaling pathway	0.0127078129867008	-4.36553827886974	226	34	0.0465753424657534	730	7161	5321,55970,9462,2258,57144,5966,1147,5578,5881,3480,4233,22800,9771,5567,10125,5159,9846,7424,5058,2264,1944,2257,22821,8822,2260,3363,5579,59345,10000,1435,5924,3082,5337,5602	PLA2G4A,GNG12,RASAL2,FGF13,PAK5,REL,CHUK,PRKCA,RAC3,IGF1R,MET,RRAS2,RAPGEF5,PRKACB,RASGRP1,PDGFRB,GAB2,VEGFC,PAK1,FGFR4,EFNA3,FGF12,RASA3,FGF17,FGFR1,HTR7,PRKCB,GNB4,AKT3,CSF1,RASGRF2,HGF,PLD1,MAPK10
ko04723	Retrograde endocannabinoid signaling	0.0127196037898417	-4.36461087015264	101	18	0.0246575342465753	730	7161	55970,2561,107,2566,2570,3709,5578,23236,57406,2770,747,5579,2775,59345,112,5603,5602,5567	GNG12,GABRB2,ADCY1,GABRG2,GABRR2,ITPR2,PRKCA,PLCB1,ABHD6,GNAI1,DAGLA,PRKCB,GNAO1,GNB4,ADCY6,MAPK13,MAPK10,PRKACB
hsa04723	Retrograde endocannabinoid signaling	0.0127196037898417	-4.36461087015264	101	18	0.0246575342465753	730	7161	55970,2561,107,2566,2570,3709,5578,23236,57406,2770,747,5579,2775,59345,112,5603,5602,5567	GNG12,GABRB2,ADCY1,GABRG2,GABRR2,ITPR2,PRKCA,PLCB1,ABHD6,GNAI1,DAGLA,PRKCB,GNAO1,GNB4,ADCY6,MAPK13,MAPK10,PRKACB
hsa00310	Lysine degradation	0.014377837958656	-4.24206728857327	59	12	0.0164383561643836	730	7161	64324,217,83852,51166,123688,1962,5352,10157,55753,23127,7468,85007	NSD1,ALDH2,SETDB2,AADAT,HYKK,EHHADH,PLOD2,AASS,OGDHL,COLGALT2,NSD2,PHYKPL
ko00310	Lysine degradation	0.014377837958656	-4.24206728857327	59	12	0.0164383561643836	730	7161	64324,217,123688,83852,1962,51166,5352,10157,55753,23127,7468,85007	NSD1,ALDH2,HYKK,SETDB2,EHHADH,AADAT,PLOD2,AASS,OGDHL,COLGALT2,NSD2,PHYKPL
hsa04540	Gap junction	0.0151758877522921	-4.18804744277292	88	16	0.0219178082191781	730	7161	10382,7846,5579,107,5592,153,112,5593,7082,3709,2977,5578,23236,5159,5567,2770	TUBB4A,TUBA1A,PRKCB,ADCY1,PRKG1,ADRB1,ADCY6,PRKG2,TJP1,ITPR2,GUCY1A2,PRKCA,PLCB1,PDGFRB,PRKACB,GNAI1
ko04540	Gap junction	0.0151758877522921	-4.18804744277292	88	16	0.0219178082191781	730	7161	10382,7846,5579,107,5592,153,112,5593,7082,3709,2977,5578,23236,5159,5567,2770	TUBB4A,TUBA1A,PRKCB,ADCY1,PRKG1,ADRB1,ADCY6,PRKG2,TJP1,ITPR2,GUCY1A2,PRKCA,PLCB1,PDGFRB,PRKACB,GNAI1
hsa04918	Thyroid hormone synthesis	0.0160528798458569	-4.13186701585328	74	14	0.0191780821917808	730	7161	64764,468,5579,107,112,3709,481,9586,5578,821,23236,7253,5567,478	CREB3L2,ATF4,PRKCB,ADCY1,ADCY6,ITPR2,ATP1B1,CREB5,PRKCA,CANX,PLCB1,TSHR,PRKACB,ATP1A3
ko04918	Thyroid hormone synthesis	0.0160528798458569	-4.13186701585328	74	14	0.0191780821917808	730	7161	64764,468,5579,107,112,3709,481,9586,5578,821,23236,7253,5567,478	CREB3L2,ATF4,PRKCB,ADCY1,ADCY6,ITPR2,ATP1B1,CREB5,PRKCA,CANX,PLCB1,TSHR,PRKACB,ATP1A3
ko04713	Circadian entrainment	0.0161439605839694	-4.12620925690202	96	17	0.0232876712328767	730	7161	55970,107,6262,51655,2977,5578,23236,9722,2770,5579,2775,59345,5592,112,5593,2906,5567	GNG12,ADCY1,RYR2,RASD1,GUCY1A2,PRKCA,PLCB1,NOS1AP,GNAI1,PRKCB,GNAO1,GNB4,PRKG1,ADCY6,PRKG2,GRIN2D,PRKACB
hsa04713	Circadian entrainment	0.0161439605839694	-4.12620925690202	96	17	0.0232876712328767	730	7161	55970,107,6262,51655,2977,5578,23236,9722,2770,5579,2775,59345,5592,112,5593,2906,5567	GNG12,ADCY1,RYR2,RASD1,GUCY1A2,PRKCA,PLCB1,NOS1AP,GNAI1,PRKCB,GNAO1,GNB4,PRKG1,ADCY6,PRKG2,GRIN2D,PRKACB
hsa04512	ECM-receptor interaction	0.0174289993900331	-4.04961982843984	82	15	0.0205479452054795	730	7161	1299,9899,3695,1292,2335,1285,7060,1286,3655,3673,3690,3912,10319,1287,1298	COL9A3,SV2B,ITGB7,COL6A2,FN1,COL4A3,THBS4,COL4A4,ITGA6,ITGA2,ITGB3,LAMB1,LAMC3,COL4A5,COL9A2
ko04512	ECM-receptor interaction	0.0174289993900331	-4.04961982843984	82	15	0.0205479452054795	730	7161	1299,9899,3695,1292,2335,1285,7060,1286,3655,3673,3690,3912,10319,1287,1298	COL9A3,SV2B,ITGB7,COL6A2,FN1,COL4A3,THBS4,COL4A4,ITGA6,ITGA2,ITGB3,LAMB1,LAMC3,COL4A5,COL9A2
hsa04725	Cholinergic synapse	0.0176301225504573	-4.03814633135107	112	19	0.026027397260274	730	7161	64764,55970,468,3786,107,8973,9586,3709,5578,23236,2770,3761,5579,10000,2775,59345,112,1131,5567	CREB3L2,GNG12,ATF4,KCNQ3,ADCY1,CHRNA6,CREB5,ITPR2,PRKCA,PLCB1,GNAI1,KCNJ4,PRKCB,AKT3,GNAO1,GNB4,ADCY6,CHRM3,PRKACB
ko04970	Salivary secretion	0.0185885130607987	-3.98521146641886	90	16	0.0219178082191781	730	7161	107,481,3709,2977,5578,23236,5579,153,5592,112,5593,490,493,1131,5567,478	ADCY1,ATP1B1,ITPR2,GUCY1A2,PRKCA,PLCB1,PRKCB,ADRB1,PRKG1,ADCY6,PRKG2,ATP2B1,ATP2B4,CHRM3,PRKACB,ATP1A3
hsa04970	Salivary secretion	0.0185885130607987	-3.98521146641886	90	16	0.0219178082191781	730	7161	107,481,3709,2977,5578,23236,5579,153,5592,112,5593,490,493,1131,5567,478	ADCY1,ATP1B1,ITPR2,GUCY1A2,PRKCA,PLCB1,PRKCB,ADRB1,PRKG1,ADCY6,PRKG2,ATP2B1,ATP2B4,CHRM3,PRKACB,ATP1A3
M00101	Cholesterol biosynthesis, squalene 2,3-epoxide => cholesterol	0.0196957185869698	-3.92735399746858	11	4	0.00547945205479452	730	7161	1595,6307,1717,1718	CYP51A1,MSMO1,DHCR7,DHCR24
hsa_M00032	Lysine degradation, lysine => saccharopine => acetoacetyl-CoA	0.0196957185869698	-3.92735399746858	11	4	0.00547945205479452	730	7161	1962,51166,10157,55753	EHHADH,AADAT,AASS,OGDHL
hsa_M00101	Cholesterol biosynthesis, squalene 2,3-epoxide => cholesterol	0.0196957185869698	-3.92735399746858	11	4	0.00547945205479452	730	7161	1595,6307,1717,1718	CYP51A1,MSMO1,DHCR7,DHCR24
M00032	Lysine degradation, lysine => saccharopine => acetoacetyl-CoA	0.0196957185869698	-3.92735399746858	11	4	0.00547945205479452	730	7161	1962,51166,10157,55753	EHHADH,AADAT,AASS,OGDHL
hsa04022	cGMP-PKG signaling pathway	0.0240326253542665	-3.72834298200684	163	25	0.0342465753424658	730	7161	64764,468,91807,107,9569,100271849,9586,481,3709,2977,23236,2770,8660,27345,10000,153,27094,5592,5593,112,493,490,4846,478,4208	CREB3L2,ATF4,MYLK3,ADCY1,GTF2IRD1,MEF2B,CREB5,ATP1B1,ITPR2,GUCY1A2,PLCB1,GNAI1,IRS2,KCNMB4,AKT3,ADRB1,KCNMB3,PRKG1,PRKG2,ADCY6,ATP2B4,ATP2B1,NOS3,ATP1A3,MEF2C
ko04022	cGMP-PKG signaling pathway	0.0240326253542665	-3.72834298200684	163	25	0.0342465753424658	730	7161	64764,468,91807,107,9569,100271849,9586,481,3709,2977,23236,2770,8660,27345,10000,153,27094,5592,5593,112,493,490,4846,478,4208	CREB3L2,ATF4,MYLK3,ADCY1,GTF2IRD1,MEF2B,CREB5,ATP1B1,ITPR2,GUCY1A2,PLCB1,GNAI1,IRS2,KCNMB4,AKT3,ADRB1,KCNMB3,PRKG1,PRKG2,ADCY6,ATP2B4,ATP2B1,NOS3,ATP1A3,MEF2C
hsa04068	FoxO signaling pathway	0.025505708816729	-3.66885297670822	132	21	0.0287671232876712	730	7161	5563,9455,116986,1147,10110,2290,23710,9454,8660,4088,114907,3480,10769,10000,23678,604,6446,5603,664,5106,5602	PRKAA2,HOMER2,AGAP2,CHUK,SGK2,FOXG1,GABARAPL1,HOMER3,IRS2,SMAD3,FBXO32,IGF1R,PLK2,AKT3,SGK3,BCL6,SGK1,MAPK13,BNIP3,PCK2,MAPK10
M00020	Serine biosynthesis, glycerate-3P => serine	0.0290266619855431	-3.53954049255367	3	2	0.00273972602739726	730	7161	26227,5723	PHGDH,PSPH
hsa_M00020	Serine biosynthesis, glycerate-3P => serine	0.0290266619855431	-3.53954049255367	3	2	0.00273972602739726	730	7161	26227,5723	PHGDH,PSPH
ko00534	Glycosaminoglycan biosynthesis - heparan sulfate / heparin	0.0298420989055167	-3.5118351674635	24	6	0.00821917808219178	730	7161	9953,11285,64131,26035,222537,266722	HS3ST3B1,B4GALT7,XYLT1,GLCE,HS3ST5,HS6ST3
hsa00534	Glycosaminoglycan biosynthesis - heparan sulfate / heparin	0.0298420989055167	-3.5118351674635	24	6	0.00821917808219178	730	7161	9953,64131,11285,26035,222537,266722	HS3ST3B1,XYLT1,B4GALT7,GLCE,HS3ST5,HS6ST3
hsa05200	Pathways in cancer	0.0304513871136069	-3.49162373205074	395	52	0.0712328767123288	730	7161	55970,9170,2335,2258,9826,8325,3655,10319,1287,1147,6777,1488,1050,5578,5881,1496,2122,3480,4609,112,4233,5159,5567,10125,2735,8321,8643,7424,1285,1630,8322,7039,1286,2257,107,7481,8822,23236,2260,2770,4088,83439,5579,59345,10000,3673,8900,3912,3082,5337,652,5602	GNG12,LPAR2,FN1,FGF13,ARHGEF11,FZD8,ITGA6,LAMC3,COL4A5,CHUK,STAT5B,CTBP2,CEBPA,PRKCA,RAC3,CTNNA2,MECOM,IGF1R,MYC,ADCY6,MET,PDGFRB,PRKACB,RASGRP1,GLI1,FZD1,PTCH2,VEGFC,COL4A3,DCC,FZD4,TGFA,COL4A4,FGF12,ADCY1,WNT11,FGF17,PLCB1,FGFR1,GNAI1,SMAD3,TCF7L1,PRKCB,GNB4,AKT3,ITGA2,CCNA1,LAMB1,HGF,PLD1,BMP4,MAPK10
ko04921	Oxytocin signaling pathway	0.0339700596798436	-3.38227573997152	152	23	0.0315068493150685	730	7161	5321,5563,10368,91807,107,6262,3709,2977,5578,785,23236,2770,3761,1938,5579,783,2775,112,5021,5567,781,4846,4208	PLA2G4A,PRKAA2,CACNG3,MYLK3,ADCY1,RYR2,ITPR2,GUCY1A2,PRKCA,CACNB4,PLCB1,GNAI1,KCNJ4,EEF2,PRKCB,CACNB2,GNAO1,ADCY6,OXTR,PRKACB,CACNA2D1,NOS3,MEF2C
hsa04921	Oxytocin signaling pathway	0.0339700596798436	-3.38227573997152	152	23	0.0315068493150685	730	7161	5321,5563,10368,91807,107,6262,3709,2977,5578,785,23236,2770,3761,1938,5579,783,2775,112,5021,5567,781,4846,4208	PLA2G4A,PRKAA2,CACNG3,MYLK3,ADCY1,RYR2,ITPR2,GUCY1A2,PRKCA,CACNB4,PLCB1,GNAI1,KCNJ4,EEF2,PRKCB,CACNB2,GNAO1,ADCY6,OXTR,PRKACB,CACNA2D1,NOS3,MEF2C
hsa04211	Longevity regulating pathway	0.0343516141871404	-3.37110626907028	89	15	0.0205479452054795	730	7161	64764,5563,8660,83667,468,3480,10000,1978,107,112,9586,9474,10891,27244,5567	CREB3L2,PRKAA2,IRS2,SESN2,ATF4,IGF1R,AKT3,EIF4EBP1,ADCY1,ADCY6,CREB5,ATG5,PPARGC1A,SESN1,PRKACB
hsa04750	Inflammatory mediator regulation of TRP channels	0.0352682961717457	-3.34477084404549	97	16	0.0219178082191781	730	7161	5321,1573,107,5588,3709,5578,23236,5579,5608,5580,41,112,5603,5602,3556,5567	PLA2G4A,CYP2J2,ADCY1,PRKCQ,ITPR2,PRKCA,PLCB1,PRKCB,MAP2K6,PRKCD,ASIC1,ADCY6,MAPK13,MAPK10,IL1RAP,PRKACB
ko04750	Inflammatory mediator regulation of TRP channels	0.0352682961717457	-3.34477084404549	97	16	0.0219178082191781	730	7161	5321,1573,107,5588,3709,5578,23236,5579,5608,5580,41,112,5603,5602,3556,5567	PLA2G4A,CYP2J2,ADCY1,PRKCQ,ITPR2,PRKCA,PLCB1,PRKCB,MAP2K6,PRKCD,ASIC1,ADCY6,MAPK13,MAPK10,IL1RAP,PRKACB
hsa_M00415	Fatty acid biosynthesis, elongation, endoplasmic reticulum	0.0362104369522494	-3.31840788810674	13	4	0.00547945205479452	730	7161	6785,79993,83401,9200	ELOVL4,ELOVL7,ELOVL3,HACD1
M00415	Fatty acid biosynthesis, elongation, endoplasmic reticulum	0.0362104369522494	-3.31840788810674	13	4	0.00547945205479452	730	7161	6785,79993,83401,9200	ELOVL4,ELOVL7,ELOVL3,HACD1
hsa04664	Fc epsilon RI signaling pathway	0.0364577598846896	-3.31160095197325	67	12	0.0164383561643836	730	7161	5321,10451,241,5608,10000,5603,5578,3937,5602,6850,5881,9846	PLA2G4A,VAV3,ALOX5AP,MAP2K6,AKT3,MAPK13,PRKCA,LCP2,MAPK10,SYK,RAC3,GAB2
ko04664	Fc epsilon RI signaling pathway	0.0364577598846896	-3.31160095197325	67	12	0.0164383561643836	730	7161	5321,10451,241,5608,10000,5603,5578,3937,5602,6850,5881,9846	PLA2G4A,VAV3,ALOX5AP,MAP2K6,AKT3,MAPK13,PRKCA,LCP2,MAPK10,SYK,RAC3,GAB2
ko04810	Regulation of actin cytoskeleton	0.0369401876744028	-3.29845522370411	211	30	0.0410958904109589	730	7161	2264,5058,3695,10451,54961,55970,5829,91807,2335,2258,57144,1793,3655,2257,221178,55740,8822,5217,5881,10458,2260,85477,2934,3071,3673,3690,128239,22800,1131,5159	FGFR4,PAK1,ITGB7,VAV3,SSH3,GNG12,PXN,MYLK3,FN1,FGF13,PAK5,DOCK1,ITGA6,FGF12,SPATA13,ENAH,FGF17,PFN2,RAC3,BAIAP2,FGFR1,SCIN,GSN,NCKAP1L,ITGA2,ITGB3,IQGAP3,RRAS2,CHRM3,PDGFRB
hsa04810	Regulation of actin cytoskeleton	0.0369401876744028	-3.29845522370411	211	30	0.0410958904109589	730	7161	2264,5058,3695,10451,54961,55970,5829,91807,2335,2258,57144,1793,3655,2257,221178,55740,8822,5217,5881,10458,2260,85477,2934,3071,3673,3690,128239,22800,1131,5159	FGFR4,PAK1,ITGB7,VAV3,SSH3,GNG12,PXN,MYLK3,FN1,FGF13,PAK5,DOCK1,ITGA6,FGF12,SPATA13,ENAH,FGF17,PFN2,RAC3,BAIAP2,FGFR1,SCIN,GSN,NCKAP1L,ITGA2,ITGB3,IQGAP3,RRAS2,CHRM3,PDGFRB
hsa04730	Long-term depression	0.0379315587769805	-3.27197182797546	60	11	0.0150684931506849	730	7161	5321,3480,5579,2775,5592,5593,3709,5578,2977,23236,2770	PLA2G4A,IGF1R,PRKCB,GNAO1,PRKG1,PRKG2,ITPR2,PRKCA,GUCY1A2,PLCB1,GNAI1
ko04730	Long-term depression	0.0379315587769805	-3.27197182797546	60	11	0.0150684931506849	730	7161	5321,3480,5579,2775,5592,5593,3709,5578,2977,23236,2770	PLA2G4A,IGF1R,PRKCB,GNAO1,PRKG1,PRKG2,ITPR2,PRKCA,GUCY1A2,PLCB1,GNAI1
hsa04971	Gastric acid secretion	0.0383687719439648	-3.26051138086578	75	13	0.0178082191780822	730	7161	91807,760,5579,107,112,3709,481,5578,23236,5567,1131,478,2770	MYLK3,CA2,PRKCB,ADCY1,ADCY6,ITPR2,ATP1B1,PRKCA,PLCB1,PRKACB,CHRM3,ATP1A3,GNAI1
ko04971	Gastric acid secretion	0.0383687719439648	-3.26051138086578	75	13	0.0178082191780822	730	7161	91807,760,5579,107,112,3709,481,5578,23236,5567,1131,478,2770	MYLK3,CA2,PRKCB,ADCY1,ADCY6,ITPR2,ATP1B1,PRKCA,PLCB1,PRKACB,CHRM3,ATP1A3,GNAI1
ko04728	Dopaminergic synapse	0.0394120212289775	-3.23368440187957	130	20	0.0273972602739726	730	7161	64764,55970,468,3798,3800,9586,3709,5578,23236,5523,2770,5579,10000,2775,59345,4128,5603,5521,5602,5567	CREB3L2,GNG12,ATF4,KIF5A,KIF5C,CREB5,ITPR2,PRKCA,PLCB1,PPP2R3A,GNAI1,PRKCB,AKT3,GNAO1,GNB4,MAOA,MAPK13,PPP2R2B,MAPK10,PRKACB
hsa04728	Dopaminergic synapse	0.0394120212289775	-3.23368440187957	130	20	0.0273972602739726	730	7161	64764,55970,468,3798,3800,9586,3709,5578,23236,5523,2770,5579,10000,2775,59345,4128,5603,5521,5602,5567	CREB3L2,GNG12,ATF4,KIF5A,KIF5C,CREB5,ITPR2,PRKCA,PLCB1,PPP2R3A,GNAI1,PRKCB,AKT3,GNAO1,GNB4,MAOA,MAPK13,PPP2R2B,MAPK10,PRKACB
ko00260	Glycine, serine and threonine metabolism	0.0399535035920964	-3.22003891118853	39	8	0.010958904109589	730	7161	23464,4128,875,26227,2628,5723,2731,1491	GCAT,MAOA,CBS,PHGDH,GATM,PSPH,GLDC,CTH
hsa00260	Glycine, serine and threonine metabolism	0.0399535035920964	-3.22003891118853	39	8	0.010958904109589	730	7161	4128,875,26227,23464,2628,5723,1491,2731	MAOA,CBS,PHGDH,GCAT,GATM,PSPH,CTH,GLDC
ko04933	AGE-RAGE signaling pathway in diabetic complications	0.0415895134045515	-3.17990722511419	99	16	0.0219178082191781	730	7161	7424,2335,1285,1286,1287,6777,5578,23236,2152,4088,5579,10000,5580,5603,5602,4846	VEGFC,FN1,COL4A3,COL4A4,COL4A5,STAT5B,PRKCA,PLCB1,F3,SMAD3,PRKCB,AKT3,PRKCD,MAPK13,MAPK10,NOS3
hsa04933	AGE-RAGE signaling pathway in diabetic complications	0.0415895134045515	-3.17990722511419	99	16	0.0219178082191781	730	7161	7424,2335,1285,1286,1287,6777,5578,23236,2152,4088,5579,10000,5580,5603,5602,4846	VEGFC,FN1,COL4A3,COL4A4,COL4A5,STAT5B,PRKCA,PLCB1,F3,SMAD3,PRKCB,AKT3,PRKCD,MAPK13,MAPK10,NOS3
hsa04923	Regulation of lipolysis in adipocytes	0.0438306224808909	-3.12742256248729	54	10	0.0136986301369863	730	7161	8660,10000,5592,107,153,112,5593,7253,5567,2770	IRS2,AKT3,PRKG1,ADCY1,ADRB1,ADCY6,PRKG2,TSHR,PRKACB,GNAI1
ko04961	Endocrine and other factor-regulated calcium reabsorption	0.0450741232361581	-3.09944696130416	47	9	0.0123287671232877	730	7161	26052,5579,112,481,5578,23236,490,5567,478	DNM3,PRKCB,ADCY6,ATP1B1,PRKCA,PLCB1,ATP2B1,PRKACB,ATP1A3
hsa04961	Endocrine and other factor-regulated calcium reabsorption	0.0450741232361581	-3.09944696130416	47	9	0.0123287671232877	730	7161	26052,5579,112,481,5578,23236,490,5567,478	DNM3,PRKCB,ADCY6,ATP1B1,PRKCA,PLCB1,ATP2B1,PRKACB,ATP1A3
ko04216	Ferroptosis	0.0456637840708928	-3.08644976634963	40	8	0.010958904109589	730	7161	23516,55240,30061,6520,2180,9474,23657,64116	SLC39A14,STEAP3,SLC40A1,SLC3A2,ACSL1,ATG5,SLC7A11,SLC39A8
ko00380	Tryptophan metabolism	0.0456637840708928	-3.08644976634963	40	8	0.010958904109589	730	7161	217,1962,51166,6999,8564,55753,4128,1545	ALDH2,EHHADH,AADAT,TDO2,KMO,OGDHL,MAOA,CYP1B1
hsa04216	Ferroptosis	0.0456637840708928	-3.08644976634963	40	8	0.010958904109589	730	7161	23516,55240,30061,6520,2180,9474,23657,64116	SLC39A14,STEAP3,SLC40A1,SLC3A2,ACSL1,ATG5,SLC7A11,SLC39A8
hsa00380	Tryptophan metabolism	0.0456637840708928	-3.08644976634963	40	8	0.010958904109589	730	7161	217,51166,1962,6999,8564,55753,4128,1545	ALDH2,AADAT,EHHADH,TDO2,KMO,OGDHL,MAOA,CYP1B1
ko00532	Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate	0.0461023521424912	-3.07689130766745	20	5	0.00684931506849315	730	7161	337876,10090,22856,11285,64131	CHSY3,UST,CHSY1,B4GALT7,XYLT1
hsa00532	Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate	0.0461023521424912	-3.07689130766745	20	5	0.00684931506849315	730	7161	337876,10090,22856,64131,11285	CHSY3,UST,CHSY1,XYLT1,B4GALT7
hsa04976	Bile secretion	0.0536960955861573	-2.92441498800345	71	12	0.0164383561643836	730	7161	760,10257,3781,3949,107,112,1244,481,57552,5567,478,3156	CA2,ABCC4,KCNN2,LDLR,ADCY1,ADCY6,ABCC2,ATP1B1,NCEH1,PRKACB,ATP1A3,HMGCR
ko04976	Bile secretion	0.0536960955861573	-2.92441498800345	71	12	0.0164383561643836	730	7161	760,10257,3781,3949,107,112,1244,481,57552,5567,478,3156	CA2,ABCC4,KCNN2,LDLR,ADCY1,ADCY6,ABCC2,ATP1B1,NCEH1,PRKACB,ATP1A3,HMGCR
M00070	Glycosphingolipid biosynthesis, lacto-series, LacCer => Lc4Cer	0.0541530679975669	-2.91594064975198	4	2	0.00273972602739726	730	7161	8708,8707	B3GALT1,B3GALT2
hsa_M00070	Glycosphingolipid biosynthesis, lacto-series, LacCer => Lc4Cer	0.0541530679975669	-2.91594064975198	4	2	0.00273972602739726	730	7161	8708,8707	B3GALT1,B3GALT2
ko04972	Pancreatic secretion	0.0564273013689557	-2.87480217077522	95	15	0.0205479452054795	730	7161	760,5579,107,6262,112,7220,3709,481,5874,5578,23236,1131,493,490,478	CA2,PRKCB,ADCY1,RYR2,ADCY6,TRPC1,ITPR2,ATP1B1,RAB27B,PRKCA,PLCB1,CHRM3,ATP2B4,ATP2B1,ATP1A3
hsa04972	Pancreatic secretion	0.0564273013689557	-2.87480217077522	95	15	0.0205479452054795	730	7161	760,5579,107,6262,112,7220,3709,481,5874,5578,23236,1131,493,490,478	CA2,PRKCB,ADCY1,RYR2,ADCY6,TRPC1,ITPR2,ATP1B1,RAB27B,PRKCA,PLCB1,CHRM3,ATP2B4,ATP2B1,ATP1A3
hsa05030	Cocaine addiction	0.0567216770294004	-2.86959883038646	49	9	0.0123287671232877	730	7161	64764,627,468,26086,4128,2906,9586,5567,2770	CREB3L2,BDNF,ATF4,GPSM1,MAOA,GRIN2D,CREB5,PRKACB,GNAI1
ko05030	Cocaine addiction	0.0567216770294004	-2.86959883038646	49	9	0.0123287671232877	730	7161	64764,627,468,26086,4128,2906,9586,5567,2770	CREB3L2,BDNF,ATF4,GPSM1,MAOA,GRIN2D,CREB5,PRKACB,GNAI1
hsa00250	Alanine, aspartate and glutamate metabolism	0.0596379727158432	-2.81946278168475	35	7	0.00958904109589041	730	7161	84706,445,18,440,57494,122622,284716	GPT2,ASS1,ABAT,ASNS,RIMKLB,ADSSL1,RIMKLA
ko00250	Alanine, aspartate and glutamate metabolism	0.0596379727158432	-2.81946278168475	35	7	0.00958904109589041	730	7161	84706,445,18,440,57494,122622,284716	GPT2,ASS1,ABAT,ASNS,RIMKLB,ADSSL1,RIMKLA
hsa04726	Serotonergic synapse	0.0605876596570918	-2.80366404266508	112	17	0.0232876712328767	730	7161	3363,5321,55970,3781,5579,2561,59345,2775,1573,4128,7220,3709,5578,23236,5567,1843,2770	HTR7,PLA2G4A,GNG12,KCNN2,PRKCB,GABRB2,GNB4,GNAO1,CYP2J2,MAOA,TRPC1,ITPR2,PRKCA,PLCB1,PRKACB,DUSP1,GNAI1
hsa04727	GABAergic synapse	0.0605921164693922	-2.80359048563363	88	14	0.0191780821917808	730	7161	55970,5579,2561,59345,2775,107,2566,112,18,2570,5578,5567,23710,2770	GNG12,PRKCB,GABRB2,GNB4,GNAO1,ADCY1,GABRG2,ADCY6,ABAT,GABRR2,PRKCA,PRKACB,GABARAPL1,GNAI1
ko04727	GABAergic synapse	0.0605921164693922	-2.80359048563363	88	14	0.0191780821917808	730	7161	55970,5579,2561,59345,2775,107,2566,112,18,2570,5578,5567,23710,2770	GNG12,PRKCB,GABRB2,GNB4,GNAO1,ADCY1,GABRG2,ADCY6,ABAT,GABRR2,PRKCA,PRKACB,GABARAPL1,GNAI1
ko05230	Central carbon metabolism in cancer	0.062530802360613	-2.77209600587462	65	11	0.0150684931506849	730	7161	5163,10000,4609,8140,3099,4916,3098,4233,6510,5159,2260	PDK1,AKT3,MYC,SLC7A5,HK2,NTRK3,HK1,MET,SLC1A5,PDGFRB,FGFR1
hsa05230	Central carbon metabolism in cancer	0.062530802360613	-2.77209600587462	65	11	0.0150684931506849	730	7161	5163,10000,4609,8140,3099,4916,3098,4233,6510,5159,2260	PDK1,AKT3,MYC,SLC7A5,HK2,NTRK3,HK1,MET,SLC1A5,PDGFRB,FGFR1
hsa04913	Ovarian steroidogenesis	0.0632120208250136	-2.76126079298818	50	9	0.0123287671232877	730	7161	5321,3480,1573,3949,107,112,654,5567,1545	PLA2G4A,IGF1R,CYP2J2,LDLR,ADCY1,ADCY6,BMP6,PRKACB,CYP1B1
ko04913	Ovarian steroidogenesis	0.0632120208250136	-2.76126079298818	50	9	0.0123287671232877	730	7161	5321,3480,1573,3949,107,112,654,5567,1545	PLA2G4A,IGF1R,CYP2J2,LDLR,ADCY1,ADCY6,BMP6,PRKACB,CYP1B1
hsa04270	Vascular smooth muscle contraction	0.0642286990157157	-2.74530514300529	121	18	0.0246575342465753	730	7161	5321,91807,9826,107,10203,5588,3709,2977,5578,23236,27345,5579,5580,5592,27094,59,112,5567	PLA2G4A,MYLK3,ARHGEF11,ADCY1,CALCRL,PRKCQ,ITPR2,GUCY1A2,PRKCA,PLCB1,KCNMB4,PRKCB,PRKCD,PRKG1,KCNMB3,ACTA2,ADCY6,PRKACB
ko04270	Vascular smooth muscle contraction	0.0642286990157157	-2.74530514300529	121	18	0.0246575342465753	730	7161	5321,91807,9826,107,10203,5588,3709,2977,5578,23236,27345,5579,5580,5592,27094,59,112,5567	PLA2G4A,MYLK3,ARHGEF11,ADCY1,CALCRL,PRKCQ,ITPR2,GUCY1A2,PRKCA,PLCB1,KCNMB4,PRKCB,PRKCD,PRKG1,KCNMB3,ACTA2,ADCY6,PRKACB
ko05414	Dilated cardiomyopathy	0.0654903435625079	-2.72585257373589	89	14	0.0191780821917808	730	7161	3695,10368,783,3655,3673,3690,107,153,112,6262,7168,785,781,5567	ITGB7,CACNG3,CACNB2,ITGA6,ITGA2,ITGB3,ADCY1,ADRB1,ADCY6,RYR2,TPM1,CACNB4,CACNA2D1,PRKACB
hsa05414	Dilated cardiomyopathy	0.0654903435625079	-2.72585257373589	89	14	0.0191780821917808	730	7161	3695,10368,783,3655,3673,3690,107,153,112,6262,7168,785,781,5567	ITGB7,CACNG3,CACNB2,ITGA6,ITGA2,ITGB3,ADCY1,ADRB1,ADCY6,RYR2,TPM1,CACNB4,CACNA2D1,PRKACB
ko00900	Terpenoid backbone biosynthesis	0.0661862194706721	-2.71528300280412	22	5	0.00684931506849315	730	7161	3157,3422,4598,4597,3156	HMGCS1,IDI1,MVK,MVD,HMGCR
hsa00900	Terpenoid backbone biosynthesis	0.0661862194706721	-2.71528300280412	22	5	0.00684931506849315	730	7161	3422,4598,3157,4597,3156	IDI1,MVK,HMGCS1,MVD,HMGCR
hsa04371	Apelin signaling pathway	0.066455051434769	-2.71122947813022	138	20	0.0273972602739726	730	7161	5563,55970,91807,107,100271849,6262,3709,23236,23710,2770,4088,10000,59345,59,112,10891,22800,5567,4846,4208	PRKAA2,GNG12,MYLK3,ADCY1,MEF2B,RYR2,ITPR2,PLCB1,GABARAPL1,GNAI1,SMAD3,AKT3,GNB4,ACTA2,ADCY6,PPARGC1A,RRAS2,PRKACB,NOS3,MEF2C
ko04024	cAMP signaling pathway	0.0704001110159834	-2.6535604388878	198	27	0.036986301369863	730	7161	64764,5058,627,10451,10257,11069,107,6262,9586,481,5881,2770,10000,153,112,2906,5337,5144,5021,22800,5602,7253,5567,490,493,478,2735	CREB3L2,PAK1,BDNF,VAV3,ABCC4,RAPGEF4,ADCY1,RYR2,CREB5,ATP1B1,RAC3,GNAI1,AKT3,ADRB1,ADCY6,GRIN2D,PLD1,PDE4D,OXTR,RRAS2,MAPK10,TSHR,PRKACB,ATP2B1,ATP2B4,ATP1A3,GLI1
hsa04024	cAMP signaling pathway	0.0704001110159834	-2.6535604388878	198	27	0.036986301369863	730	7161	64764,5058,627,10451,10257,11069,107,6262,9586,481,5881,2770,10000,153,112,2906,5337,5144,5021,22800,5602,7253,5567,490,493,478,2735	CREB3L2,PAK1,BDNF,VAV3,ABCC4,RAPGEF4,ADCY1,RYR2,CREB5,ATP1B1,RAC3,GNAI1,AKT3,ADRB1,ADCY6,GRIN2D,PLD1,PDE4D,OXTR,RRAS2,MAPK10,TSHR,PRKACB,ATP2B1,ATP2B4,ATP1A3,GLI1
hsa04925	Aldosterone synthesis and secretion	0.0704388969170736	-2.65300965537065	82	13	0.0178082191780822	730	7161	64764,747,468,5579,3164,3949,107,112,3709,9586,5578,23236,5567	CREB3L2,DAGLA,ATF4,PRKCB,NR4A1,LDLR,ADCY1,ADCY6,ITPR2,CREB5,PRKCA,PLCB1,PRKACB
ko04925	Aldosterone synthesis and secretion	0.0704388969170736	-2.65300965537065	82	13	0.0178082191780822	730	7161	64764,747,468,5579,3164,3949,107,112,3709,9586,5578,23236,5567	CREB3L2,DAGLA,ATF4,PRKCB,NR4A1,LDLR,ADCY1,ADCY6,ITPR2,CREB5,PRKCA,PLCB1,PRKACB
M00695	cAMP signaling	0.0722433755441504	-2.62771464416343	16	4	0.00547945205479452	730	7161	112,5567,2770,107	ADCY6,PRKACB,GNAI1,ADCY1
hsa_M00695	cAMP signaling	0.0722433755441504	-2.62771464416343	16	4	0.00547945205479452	730	7161	112,5567,2770,107	ADCY6,PRKACB,GNAI1,ADCY1
ko04370	VEGF signaling pathway	0.0729830019934251	-2.61752871435251	59	10	0.0136986301369863	730	7161	9261,5321,5829,9047,5579,10000,5603,5578,5881,4846	MAPKAPK2,PLA2G4A,PXN,SH2D2A,PRKCB,AKT3,MAPK13,PRKCA,RAC3,NOS3
hsa04370	VEGF signaling pathway	0.0729830019934251	-2.61752871435251	59	10	0.0136986301369863	730	7161	9261,5321,5829,9047,5579,10000,5603,5578,5881,4846	MAPKAPK2,PLA2G4A,PXN,SH2D2A,PRKCB,AKT3,MAPK13,PRKCA,RAC3,NOS3
hsa_M00177	Ribosome, eukaryotes	0.0760612406693677	-2.57621646489579	91	14	0.0191780821917808	730	7161	6224,51187,6154,6136,6158,6205,6144,6124,6206,51121,23521,6228,6164,6207	RPS20,RSL24D1,RPL26,RPL12,RPL28,RPS11,RPL21,RPL4,RPS12,RPL26L1,RPL13A,RPS23,RPL34,RPS13
M00177	Ribosome, eukaryotes	0.0760612406693677	-2.57621646489579	91	14	0.0191780821917808	730	7161	6224,51187,6154,6136,6158,6205,6144,6124,6206,51121,23521,6228,6164,6207	RPS20,RSL24D1,RPL26,RPL12,RPL28,RPS11,RPL21,RPL4,RPS12,RPL26L1,RPL13A,RPS23,RPL34,RPS13
ko04960	Aldosterone-regulated sodium reabsorption	0.0766447429175005	-2.56857426156761	37	7	0.00958904109589041	730	7161	6446,481,5578,5579,4306,2810,478	SGK1,ATP1B1,PRKCA,PRKCB,NR3C2,SFN,ATP1A3
hsa04960	Aldosterone-regulated sodium reabsorption	0.0766447429175005	-2.56857426156761	37	7	0.00958904109589041	730	7161	6446,481,5578,5579,4306,2810,478	SGK1,ATP1B1,PRKCA,PRKCB,NR3C2,SFN,ATP1A3
ko04668	TNF signaling pathway	0.0801044245820716	-2.52442418820529	108	16	0.0219178082191781	730	7161	64764,7424,468,3600,1147,9586,8809,1051,3627,10000,1435,5608,7132,5603,153090,5602	CREB3L2,VEGFC,ATF4,IL15,CHUK,CREB5,IL18R1,CEBPB,CXCL10,AKT3,CSF1,MAP2K6,TNFRSF1A,MAPK13,DAB2IP,MAPK10
hsa04668	TNF signaling pathway	0.0801044245820716	-2.52442418820529	108	16	0.0219178082191781	730	7161	64764,7424,468,3600,1147,9586,8809,1051,3627,10000,1435,5608,7132,5603,153090,5602	CREB3L2,VEGFC,ATF4,IL15,CHUK,CREB5,IL18R1,CEBPB,CXCL10,AKT3,CSF1,MAP2K6,TNFRSF1A,MAPK13,DAB2IP,MAPK10
ko04912	GnRH signaling pathway	0.0817395370276709	-2.50421746482497	92	14	0.0191780821917808	730	7161	5321,468,5579,5608,5580,107,112,5603,5337,3709,5578,23236,5602,5567	PLA2G4A,ATF4,PRKCB,MAP2K6,PRKCD,ADCY1,ADCY6,MAPK13,PLD1,ITPR2,PRKCA,PLCB1,MAPK10,PRKACB
hsa04912	GnRH signaling pathway	0.0817395370276709	-2.50421746482497	92	14	0.0191780821917808	730	7161	5321,468,5579,5608,5580,107,112,5603,5337,3709,5578,23236,5602,5567	PLA2G4A,ATF4,PRKCB,MAP2K6,PRKCD,ADCY1,ADCY6,MAPK13,PLD1,ITPR2,PRKCA,PLCB1,MAPK10,PRKACB
M00057	Glycosaminoglycan biosynthesis, linkage tetrasaccharide	0.0842471789843001	-2.47400019417614	5	2	0.00273972602739726	730	7161	11285,64131	B4GALT7,XYLT1
hsa00524	Neomycin, kanamycin and gentamicin biosynthesis	0.0842471789843001	-2.47400019417614	5	2	0.00273972602739726	730	7161	3098,3099	HK1,HK2
hsa_M00057	Glycosaminoglycan biosynthesis, linkage tetrasaccharide	0.0842471789843001	-2.47400019417614	5	2	0.00273972602739726	730	7161	11285,64131	B4GALT7,XYLT1
ko00524	Neomycin, kanamycin and gentamicin biosynthesis	0.0842471789843001	-2.47400019417614	5	2	0.00273972602739726	730	7161	3098,3099	HK1,HK2
M00089	Triacylglycerol biosynthesis	0.0871698028470449	-2.4398973056677	17	4	0.00547945205479452	730	7161	8611,129642,56895,8612	PLPP1,MBOAT2,AGPAT4,PLPP2
hsa_M00089	Triacylglycerol biosynthesis	0.0871698028470449	-2.4398973056677	17	4	0.00547945205479452	730	7161	8611,129642,56895,8612	PLPP1,MBOAT2,AGPAT4,PLPP2
ko04920	Adipocytokine signaling pathway	0.08839393680423	-2.42595189987826	69	11	0.0150684931506849	730	7161	5563,8660,2180,10000,7132,1147,5588,5106,10891,5602,3953	PRKAA2,IRS2,ACSL1,AKT3,TNFRSF1A,CHUK,PRKCQ,PCK2,PPARGC1A,MAPK10,LEPR
hsa04920	Adipocytokine signaling pathway	0.08839393680423	-2.42595189987826	69	11	0.0150684931506849	730	7161	5563,8660,2180,10000,7132,1147,5588,5106,10891,5602,3953	PRKAA2,IRS2,ACSL1,AKT3,TNFRSF1A,CHUK,PRKCQ,PCK2,PPARGC1A,MAPK10,LEPR
hsa04310	Wnt signaling pathway	0.0886856133226548	-2.42265759760565	143	20	0.0273972602739726	730	7161	8322,8325,144165,1488,7481,147111,5578,23236,5881,22943,4088,83439,5579,4609,4040,166336,5602,8945,5567,8321	FZD4,FZD8,PRICKLE1,CTBP2,WNT11,NOTUM,PRKCA,PLCB1,RAC3,DKK1,SMAD3,TCF7L1,PRKCB,MYC,LRP6,PRICKLE2,MAPK10,BTRC,PRKACB,FZD1
ko04310	Wnt signaling pathway	0.0886856133226548	-2.42265759760565	143	20	0.0273972602739726	730	7161	8322,8325,144165,1488,7481,147111,5578,23236,5881,22943,4088,83439,5579,4609,4040,166336,5602,8945,5567,8321	FZD4,FZD8,PRICKLE1,CTBP2,WNT11,NOTUM,PRKCA,PLCB1,RAC3,DKK1,SMAD3,TCF7L1,PRKCB,MYC,LRP6,PRICKLE2,MAPK10,BTRC,PRKACB,FZD1
ko04071	Sphingolipid signaling pathway	0.0894063845376715	-2.41456318394243	118	17	0.0232876712328767	730	7161	5578,23236,5881,5523,2770,5579,340485,10000,7132,5603,79603,5337,5521,10715,5602,4846,9846	PRKCA,PLCB1,RAC3,PPP2R3A,GNAI1,PRKCB,ACER2,AKT3,TNFRSF1A,MAPK13,CERS4,PLD1,PPP2R2B,CERS1,MAPK10,NOS3,GAB2
hsa04071	Sphingolipid signaling pathway	0.0894063845376715	-2.41456318394243	118	17	0.0232876712328767	730	7161	5578,23236,5881,5523,2770,5579,340485,10000,7132,5603,79603,5337,5521,10715,5602,4846,9846	PRKCA,PLCB1,RAC3,PPP2R3A,GNAI1,PRKCB,ACER2,AKT3,TNFRSF1A,MAPK13,CERS4,PLD1,PPP2R2B,CERS1,MAPK10,NOS3,GAB2
M00091	Phosphatidylcholine (PC) biosynthesis, PE => PC	0.101941069682454	-2.28336038086991	1	1	0.00136986301369863	730	7161	10400	PEMT
hsa_M00091	Phosphatidylcholine (PC) biosynthesis, PE => PC	0.101941069682454	-2.28336038086991	1	1	0.00136986301369863	730	7161	10400	PEMT
hsa00770	Pantothenate and CoA biosynthesis	0.103452825335919	-2.26863956403816	18	4	0.00547945205479452	730	7161	8875,5167,79646,53354	VNN2,ENPP1,PANK3,PANK1
ko01210	2-Oxocarboxylic acid metabolism	0.103452825335919	-2.26863956403816	18	4	0.00547945205479452	730	7161	84706,100526760,51166,48	GPT2,ABHD14A-ACY1,AADAT,ACO1
hsa01210	2-Oxocarboxylic acid metabolism	0.103452825335919	-2.26863956403816	18	4	0.00547945205479452	730	7161	84706,100526760,51166,48	GPT2,ABHD14A-ACY1,AADAT,ACO1
ko00770	Pantothenate and CoA biosynthesis	0.103452825335919	-2.26863956403816	18	4	0.00547945205479452	730	7161	8875,5167,79646,53354	VNN2,ENPP1,PANK3,PANK1
hsa04060	Cytokine-cytokine receptor interaction	0.112210568209304	-2.18737809951545	270	34	0.0465753424657534	730	7161	643,90,659,60401,3600,10673,3597,8794,55504,8809,53342,2690,92,4233,8792,3556,5159,7424,93,958,3953,3626,3627,1896,1435,83729,7132,9966,3082,657,608,7292,3581,3977	CXCR5,ACVR1,BMPR2,EDA2R,IL15,TNFSF13B,IL13RA1,TNFRSF10C,TNFRSF19,IL18R1,IL17D,GHR,ACVR2A,MET,TNFRSF11A,IL1RAP,PDGFRB,VEGFC,ACVR2B,CD40,LEPR,INHBC,CXCL10,EDA,CSF1,INHBE,TNFRSF1A,TNFSF15,HGF,BMPR1A,TNFRSF17,TNFSF4,IL9R,LIFR
ko04060	Cytokine-cytokine receptor interaction	0.112210568209304	-2.18737809951545	270	34	0.0465753424657534	730	7161	643,90,659,60401,3600,10673,3597,8794,55504,8809,53342,2690,92,4233,8792,3556,5159,7424,93,958,3953,3626,3627,1896,1435,83729,7132,9966,3082,657,608,7292,3581,3977	CXCR5,ACVR1,BMPR2,EDA2R,IL15,TNFSF13B,IL13RA1,TNFRSF10C,TNFRSF19,IL18R1,IL17D,GHR,ACVR2A,MET,TNFRSF11A,IL1RAP,PDGFRB,VEGFC,ACVR2B,CD40,LEPR,INHBC,CXCL10,EDA,CSF1,INHBE,TNFRSF1A,TNFSF15,HGF,BMPR1A,TNFRSF17,TNFSF4,IL9R,LIFR
ko00051	Fructose and mannose metabolism	0.113265998868057	-2.17801625423859	33	6	0.00821917808219178	730	7161	5210,3098,5208,230,226,3099	PFKFB4,HK1,PFKFB2,ALDOC,ALDOA,HK2
hsa00051	Fructose and mannose metabolism	0.113265998868057	-2.17801625423859	33	6	0.00821917808219178	730	7161	5210,3098,5208,230,226,3099	PFKFB4,HK1,PFKFB2,ALDOC,ALDOA,HK2
hsa_M00002	Glycolysis, core module involving three-carbon compounds	0.11572095998446	-2.15657350315628	12	3	0.00410958904109589	730	7161	2597,2026,2023	GAPDH,ENO2,ENO1
M00002	Glycolysis, core module involving three-carbon compounds	0.11572095998446	-2.15657350315628	12	3	0.00410958904109589	730	7161	2597,2026,2023	GAPDH,ENO2,ENO1
M00058	Glycosaminoglycan biosynthesis, chondroitin sulfate backbone	0.118037869563587	-2.13674977749803	6	2	0.00273972602739726	730	7161	337876,22856	CHSY3,CHSY1
hsa_M00058	Glycosaminoglycan biosynthesis, chondroitin sulfate backbone	0.118037869563587	-2.13674977749803	6	2	0.00273972602739726	730	7161	337876,22856	CHSY3,CHSY1
hsa01524	Platinum drug resistance	0.119934586547278	-2.12080879693373	73	11	0.0150684931506849	730	7161	2946,119391,5366,10000,4259,2948,540,2947,27113,9446,1244	GSTM2,GSTO2,PMAIP1,AKT3,MGST3,GSTM4,ATP7B,GSTM3,BBC3,GSTO1,ABCC2
ko01524	Platinum drug resistance	0.119934586547278	-2.12080879693373	73	11	0.0150684931506849	730	7161	2946,119391,5366,10000,4259,2948,540,2947,27113,9446,1244	GSTM2,GSTO2,PMAIP1,AKT3,MGST3,GSTM4,ATP7B,GSTM3,BBC3,GSTO1,ABCC2
ko04915	Estrogen signaling pathway	0.121387089326613	-2.10877075422782	98	14	0.0191780821917808	730	7161	64764,468,2775,10000,5580,107,112,3709,9586,23236,3306,5567,4846,2770	CREB3L2,ATF4,GNAO1,AKT3,PRKCD,ADCY1,ADCY6,ITPR2,CREB5,PLCB1,HSPA2,PRKACB,NOS3,GNAI1
hsa04915	Estrogen signaling pathway	0.121387089326613	-2.10877075422782	98	14	0.0191780821917808	730	7161	64764,468,2775,10000,5580,107,112,3709,9586,23236,3306,5567,4846,2770	CREB3L2,ATF4,GNAO1,AKT3,PRKCD,ADCY1,ADCY6,ITPR2,CREB5,PLCB1,HSPA2,PRKACB,NOS3,GNAI1
hsa05205	Proteoglycans in cancer	0.130317467682719	-2.03778174640938	203	26	0.0356164383561644	730	7161	5058,5829,2335,8322,5777,287,8325,7481,3709,5578,2260,3480,10855,5579,4609,10000,3673,3690,5603,3082,2017,4233,22800,7099,5567,8321	PAK1,PXN,FN1,FZD4,PTPN6,ANK2,FZD8,WNT11,ITPR2,PRKCA,FGFR1,IGF1R,HPSE,PRKCB,MYC,AKT3,ITGA2,ITGB3,MAPK13,HGF,CTTN,MET,RRAS2,TLR4,PRKACB,FZD1
ko05205	Proteoglycans in cancer	0.130317467682719	-2.03778174640938	203	26	0.0356164383561644	730	7161	5058,5829,2335,8322,5777,287,8325,7481,3709,5578,2260,3480,10855,5579,4609,10000,3673,3690,5603,3082,2017,4233,22800,7099,5567,8321	PAK1,PXN,FN1,FZD4,PTPN6,ANK2,FZD8,WNT11,ITPR2,PRKCA,FGFR1,IGF1R,HPSE,PRKCB,MYC,AKT3,ITGA2,ITGB3,MAPK13,HGF,CTTN,MET,RRAS2,TLR4,PRKACB,FZD1
hsa00601	Glycosphingolipid biosynthesis - lacto and neolacto series	0.134002026405345	-2.00990035671762	27	5	0.00684931506849315	730	7161	2651,8708,6489,10690,8707	GCNT2,B3GALT1,ST8SIA1,FUT9,B3GALT2
ko00601	Glycosphingolipid biosynthesis - lacto and neolacto series	0.134002026405345	-2.00990035671762	27	5	0.00684931506849315	730	7161	8708,6489,2651,10690,8707	B3GALT1,ST8SIA1,GCNT2,FUT9,B3GALT2
ko04514	Cell adhesion molecules (CAMs)	0.137706139704444	-1.98263328670017	143	19	0.026027397260274	730	7161	3695,80381,3655,6402,9672,57502,958,9378,83700,257194,4756,5788,4685,4684,1000,58494,22854,100506658,1272	ITGB7,CD276,ITGA6,SELL,SDC3,NLGN4X,CD40,NRXN1,JAM3,NEGR1,NEO1,PTPRC,NCAM2,NCAM1,CDH2,JAM2,NTNG1,OCLN,CNTN1
hsa04514	Cell adhesion molecules (CAMs)	0.137706139704444	-1.98263328670017	143	19	0.026027397260274	730	7161	3695,80381,3655,6402,9672,57502,958,9378,83700,257194,4756,5788,4685,4684,1000,58494,22854,100506658,1272	ITGB7,CD276,ITGA6,SELL,SDC3,NLGN4X,CD40,NRXN1,JAM3,NEGR1,NEO1,PTPRC,NCAM2,NCAM1,CDH2,JAM2,NTNG1,OCLN,CNTN1
hsa00061	Fatty acid biosynthesis	0.139574116893244	-1.96915951491844	13	3	0.00410958904109589	730	7161	2180,55301,2194	ACSL1,OLAH,FASN
ko00061	Fatty acid biosynthesis	0.139574116893244	-1.96915951491844	13	3	0.00410958904109589	730	7161	2180,55301,2194	ACSL1,OLAH,FASN
hsa05222	Small cell lung cancer	0.143863328162795	-1.9388915400768	84	12	0.0164383561643836	730	7161	2335,1285,10000,1286,4609,3655,3673,3912,10319,1287,1147,2272	FN1,COL4A3,AKT3,COL4A4,MYC,ITGA6,ITGA2,LAMB1,LAMC3,COL4A5,CHUK,FHIT
ko05222	Small cell lung cancer	0.143863328162795	-1.9388915400768	84	12	0.0164383561643836	730	7161	2335,1285,10000,1286,4609,3655,3673,3912,10319,1287,1147,2272	FN1,COL4A3,AKT3,COL4A4,MYC,ITGA6,ITGA2,LAMB1,LAMC3,COL4A5,CHUK,FHIT
hsa04916	Melanogenesis	0.144763923904323	-1.93265097437928	101	14	0.0191780821917808	730	7161	64764,83439,5579,8322,2775,8325,107,112,7481,5578,23236,5567,2770,8321	CREB3L2,TCF7L1,PRKCB,FZD4,GNAO1,FZD8,ADCY1,ADCY6,WNT11,PRKCA,PLCB1,PRKACB,GNAI1,FZD1
hsa04066	HIF-1 signaling pathway	0.144763923904323	-1.93265097437928	101	14	0.0191780821917808	730	7161	2597,5163,3480,2026,5579,10000,1978,226,3099,3098,5578,7099,2023,4846	GAPDH,PDK1,IGF1R,ENO2,PRKCB,AKT3,EIF4EBP1,ALDOA,HK2,HK1,PRKCA,TLR4,ENO1,NOS3
ko04916	Melanogenesis	0.144763923904323	-1.93265097437928	101	14	0.0191780821917808	730	7161	64764,83439,5579,8322,2775,8325,107,112,7481,5578,23236,5567,2770,8321	CREB3L2,TCF7L1,PRKCB,FZD4,GNAO1,FZD8,ADCY1,ADCY6,WNT11,PRKCA,PLCB1,PRKACB,GNAI1,FZD1
ko04140	Autophagy - animal	0.146838548655912	-1.91842160424931	127	17	0.0232876712328767	730	7161	5563,8673,64798,5588,54541,23710,8660,3480,10000,2081,5580,664,9474,22800,5602,5567,58528	PRKAA2,VAMP8,DEPTOR,PRKCQ,DDIT4,GABARAPL1,IRS2,IGF1R,AKT3,ERN1,PRKCD,BNIP3,ATG5,RRAS2,MAPK10,PRKACB,RRAGD
hsa04140	Autophagy - animal	0.146838548655912	-1.91842160424931	127	17	0.0232876712328767	730	7161	5563,8673,64798,5588,54541,23710,8660,3480,10000,2081,5580,664,9474,22800,5602,5567,58528	PRKAA2,VAMP8,DEPTOR,PRKCQ,DDIT4,GABARAPL1,IRS2,IGF1R,AKT3,ERN1,PRKCD,BNIP3,ATG5,RRAS2,MAPK10,PRKACB,RRAGD
hsa00650	Butanoate metabolism	0.150292038506536	-1.89517495430793	28	5	0.00684931506849315	730	7161	18,3157,1962,6296,56898	ABAT,HMGCS1,EHHADH,ACSM3,BDH2
ko00650	Butanoate metabolism	0.150292038506536	-1.89517495430793	28	5	0.00684931506849315	730	7161	3157,18,1962,6296,56898	HMGCS1,ABAT,EHHADH,ACSM3,BDH2
hsa04012	ErbB signaling pathway	0.152985617502655	-1.8774113652589	85	12	0.0164383561643836	730	7161	5058,685,10718,57144,5579,1978,10000,4609,7039,6777,5578,5602	PAK1,BTC,NRG3,PAK5,PRKCB,EIF4EBP1,AKT3,MYC,TGFA,STAT5B,PRKCA,MAPK10
ko04012	ErbB signaling pathway	0.152985617502655	-1.8774113652589	85	12	0.0164383561643836	730	7161	5058,685,10718,57144,5579,10000,1978,4609,7039,6777,5578,5602	PAK1,BTC,NRG3,PAK5,PRKCB,AKT3,EIF4EBP1,MYC,TGFA,STAT5B,PRKCA,MAPK10
M00549	Nucleotide sugar biosynthesis, glucose => UDP-glucose	0.154460975364671	-1.86781380118615	7	2	0.00273972602739726	730	7161	3098,3099	HK1,HK2
hsa_M00120	Coenzyme A biosynthesis, pantothenate => CoA	0.154460975364671	-1.86781380118615	7	2	0.00273972602739726	730	7161	79646,53354	PANK3,PANK1
M00120	Coenzyme A biosynthesis, pantothenate => CoA	0.154460975364671	-1.86781380118615	7	2	0.00273972602739726	730	7161	79646,53354	PANK3,PANK1
hsa_M00549	Nucleotide sugar biosynthesis, glucose => UDP-glucose	0.154460975364671	-1.86781380118615	7	2	0.00273972602739726	730	7161	3098,3099	HK1,HK2
ko04962	Vasopressin-regulated water reabsorption	0.155735823671326	-1.85959414522389	44	7	0.00958904109589041	730	7161	64764,112,9586,79659,1780,5567,51626	CREB3L2,ADCY6,CREB5,DYNC2H1,DYNC1I1,PRKACB,DYNC2LI1
hsa04962	Vasopressin-regulated water reabsorption	0.155735823671326	-1.85959414522389	44	7	0.00958904109589041	730	7161	64764,112,9586,79659,1780,5567,51626	CREB3L2,ADCY6,CREB5,DYNC2H1,DYNC1I1,PRKACB,DYNC2LI1
ko00220	Arginine biosynthesis	0.159523369246237	-1.83556485183922	21	4	0.00547945205479452	730	7161	84706,445,100526760,4846	GPT2,ASS1,ABHD14A-ACY1,NOS3
hsa00220	Arginine biosynthesis	0.159523369246237	-1.83556485183922	21	4	0.00547945205479452	730	7161	84706,445,100526760,4846	GPT2,ASS1,ABHD14A-ACY1,NOS3
ko00760	Nicotinate and nicotinamide metabolism	0.167365377982916	-1.78757596440273	29	5	0.00684931506849315	730	7161	5167,349565,4860,83594,23475	ENPP1,NMNAT3,PNP,NUDT12,QPRT
hsa00760	Nicotinate and nicotinamide metabolism	0.167365377982916	-1.78757596440273	29	5	0.00684931506849315	730	7161	349565,5167,4860,83594,23475	NMNAT3,ENPP1,PNP,NUDT12,QPRT
ko00565	Ether lipid metabolism	0.169314021807189	-1.77600017102106	45	7	0.00958904109589041	730	7161	5321,8611,5337,7368,133121,54947,8612	PLA2G4A,PLPP1,PLD1,UGT8,ENPP6,LPCAT2,PLPP2
hsa00565	Ether lipid metabolism	0.169314021807189	-1.77600017102106	45	7	0.00958904109589041	730	7161	5321,8611,5337,7368,133121,54947,8612	PLA2G4A,PLPP1,PLD1,UGT8,ENPP6,LPCAT2,PLPP2
hsa04662	B cell receptor signaling pathway	0.171675140677626	-1.7621513050342	70	10	0.0136986301369863	730	7161	10451,3636,5579,118788,5777,10000,1380,1147,6850,5881	VAV3,INPPL1,PRKCB,PIK3AP1,PTPN6,AKT3,CR2,CHUK,SYK,RAC3
ko04662	B cell receptor signaling pathway	0.171675140677626	-1.7621513050342	70	10	0.0136986301369863	730	7161	10451,3636,5579,118788,5777,10000,1380,1147,6850,5881	VAV3,INPPL1,PRKCB,PIK3AP1,PTPN6,AKT3,CR2,CHUK,SYK,RAC3
hsa05145	Toxoplasmosis	0.173353805151318	-1.75242065640659	113	15	0.0205479452054795	730	7161	5608,2775,10000,3655,3949,3912,7132,10319,1147,5603,958,5602,7099,3306,2770	MAP2K6,GNAO1,AKT3,ITGA6,LDLR,LAMB1,TNFRSF1A,LAMC3,CHUK,MAPK13,CD40,MAPK10,TLR4,HSPA2,GNAI1
ko05145	Toxoplasmosis	0.173353805151318	-1.75242065640659	113	15	0.0205479452054795	730	7161	5608,2775,10000,3655,3949,3912,7132,10319,1147,5603,958,5602,7099,3306,2770	MAP2K6,GNAO1,AKT3,ITGA6,LDLR,LAMB1,TNFRSF1A,LAMC3,CHUK,MAPK13,CD40,MAPK10,TLR4,HSPA2,GNAI1
ko04213	Longevity regulating pathway - multiple species	0.176071923746826	-1.73686270976936	62	9	0.0123287671232877	730	7161	5563,8660,3480,10000,107,112,9474,3306,5567	PRKAA2,IRS2,IGF1R,AKT3,ADCY1,ADCY6,ATG5,HSPA2,PRKACB
hsa04213	Longevity regulating pathway - multiple species	0.176071923746826	-1.73686270976936	62	9	0.0123287671232877	730	7161	5563,8660,3480,10000,107,112,9474,3306,5567	PRKAA2,IRS2,IGF1R,AKT3,ADCY1,ADCY6,ATG5,HSPA2,PRKACB
ko00514	Other types of O-glycan biosynthesis	0.180264958084927	-1.71332752104559	22	4	0.00547945205479452	730	7161	23127,727936,145173,6480	COLGALT2,GXYLT2,B3GLCT,ST6GAL1
hsa00514	Other types of O-glycan biosynthesis	0.180264958084927	-1.71332752104559	22	4	0.00547945205479452	730	7161	23127,727936,145173,6480	COLGALT2,GXYLT2,B3GLCT,ST6GAL1
ko01200	Carbon metabolism	0.18208523487281	-1.70328037805757	114	15	0.0205479452054795	730	7161	84706,2597,1962,2026,230,226,55753,3099,48,3098,26227,2098,2023,5723,2731	GPT2,GAPDH,EHHADH,ENO2,ALDOC,ALDOA,OGDHL,HK2,ACO1,HK1,PHGDH,ESD,ENO1,PSPH,GLDC
hsa01200	Carbon metabolism	0.18208523487281	-1.70328037805757	114	15	0.0205479452054795	730	7161	84706,2597,1962,2026,230,226,55753,3099,48,3098,26227,2098,2023,5723,2731	GPT2,GAPDH,EHHADH,ENO2,ALDOC,ALDOA,OGDHL,HK2,ACO1,HK1,PHGDH,ESD,ENO1,PSPH,GLDC
hsa00603	Glycosphingolipid biosynthesis - globo and isoglobo series	0.191435363160114	-1.65320505652724	15	3	0.00410958904109589	730	7161	26301,6489,10690	GBGT1,ST8SIA1,FUT9
hsa00730	Thiamine metabolism	0.191435363160114	-1.65320505652724	15	3	0.00410958904109589	730	7161	205,203,27010	AK4,AK1,TPK1
ko00730	Thiamine metabolism	0.191435363160114	-1.65320505652724	15	3	0.00410958904109589	730	7161	205,203,27010	AK4,AK1,TPK1
hsa_M00406	TREX complex	0.192630394459861	-1.64698198075093	8	2	0.00273972602739726	730	7161	8563,84321	THOC5,THOC3
ko00740	Riboflavin metabolism	0.192630394459861	-1.64698198075093	8	2	0.00273972602739726	730	7161	5167,645	ENPP1,BLVRB
M00406	TREX complex	0.192630394459861	-1.64698198075093	8	2	0.00273972602739726	730	7161	8563,84321	THOC5,THOC3
hsa00740	Riboflavin metabolism	0.192630394459861	-1.64698198075093	8	2	0.00273972602739726	730	7161	5167,645	ENPP1,BLVRB
hsa05221	Acute myeloid leukemia	0.193286696083916	-1.64358072036189	55	8	0.010958904109589	730	7161	83439,1978,10000,4609,8900,6777,1050,1147	TCF7L1,EIF4EBP1,AKT3,MYC,CCNA1,STAT5B,CEBPA,CHUK
ko05217	Basal cell carcinoma	0.193286696083916	-1.64358072036189	55	8	0.010958904109589	730	7161	8643,83439,8322,8325,7481,652,8321,2735	PTCH2,TCF7L1,FZD4,FZD8,WNT11,BMP4,FZD1,GLI1
ko05221	Acute myeloid leukemia	0.193286696083916	-1.64358072036189	55	8	0.010958904109589	730	7161	83439,1978,10000,4609,8900,6777,1050,1147	TCF7L1,EIF4EBP1,AKT3,MYC,CCNA1,STAT5B,CEBPA,CHUK
hsa05217	Basal cell carcinoma	0.193286696083916	-1.64358072036189	55	8	0.010958904109589	730	7161	8643,83439,8322,8325,7481,652,8321,2735	PTCH2,TCF7L1,FZD4,FZD8,WNT11,BMP4,FZD1,GLI1
hsa00300	Lysine biosynthesis	0.193502943856752	-1.64246255289804	2	1	0.00136986301369863	730	7161	51166	AADAT
hsa_M00083	Fatty acid biosynthesis, elongation	0.193502943856752	-1.64246255289804	2	1	0.00136986301369863	730	7161	2194	FASN
M00083	Fatty acid biosynthesis, elongation	0.193502943856752	-1.64246255289804	2	1	0.00136986301369863	730	7161	2194	FASN
hsa_M00066	Lactosylceramide biosynthesis	0.193502943856752	-1.64246255289804	2	1	0.00136986301369863	730	7161	9331	B4GALT6
M00066	Lactosylceramide biosynthesis	0.193502943856752	-1.64246255289804	2	1	0.00136986301369863	730	7161	9331	B4GALT6
ko00300	Lysine biosynthesis	0.193502943856752	-1.64246255289804	2	1	0.00136986301369863	730	7161	51166	AADAT
M00067	Sulfoglycolipids biosynthesis, ceramide/1-alkyl-2-acylglycerol => sulfatide/seminolipid	0.193502943856752	-1.64246255289804	2	1	0.00136986301369863	730	7161	7368	UGT8
hsa_M00067	Sulfoglycolipids biosynthesis, ceramide/1-alkyl-2-acylglycerol => sulfatide/seminolipid	0.193502943856752	-1.64246255289804	2	1	0.00136986301369863	730	7161	7368	UGT8
hsa04340	Hedgehog signaling pathway	0.197931170846003	-1.61983593071202	47	7	0.00958904109589041	730	7161	8643,157,5567,8945,23432,2619,2735	PTCH2,GRK3,PRKACB,BTRC,GPR161,GAS1,GLI1
ko04340	Hedgehog signaling pathway	0.197931170846003	-1.61983593071202	47	7	0.00958904109589041	730	7161	8643,157,5567,8945,23432,2619,2735	PTCH2,GRK3,PRKACB,BTRC,GPR161,GAS1,GLI1
ko00600	Sphingolipid metabolism	0.197931170846003	-1.61983593071202	47	7	0.00958904109589041	730	7161	8611,79603,7368,10715,340485,9331,8612	PLPP1,CERS4,UGT8,CERS1,ACER2,B4GALT6,PLPP2
hsa00600	Sphingolipid metabolism	0.197931170846003	-1.61983593071202	47	7	0.00958904109589041	730	7161	8611,7368,79603,10715,340485,8612,9331	PLPP1,UGT8,CERS4,CERS1,ACER2,PLPP2,B4GALT6
ko04144	Endocytosis	0.199785359809091	-1.61051168968115	260	31	0.0424657534246575	730	7161	2264,116984,26052,3798,9265,9829,3949,55616,3800,23362,116986,2870,157,4734,9372,26056,4088,155382,6456,3480,644150,30845,11031,153,138429,5337,4233,23096,23111,3306,92421	FGFR4,ARAP2,DNM3,KIF5A,CYTH3,DNAJC6,LDLR,ASAP3,KIF5C,PSD3,AGAP2,GRK6,GRK3,NEDD4,ZFYVE9,RAB11FIP5,SMAD3,VPS37D,SH3GL2,IGF1R,WIPF3,EHD3,RAB31,ADRB1,PIP5KL1,PLD1,MET,IQSEC2,SPART,HSPA2,CHMP4C
hsa04144	Endocytosis	0.199785359809091	-1.61051168968115	260	31	0.0424657534246575	730	7161	2264,116984,26052,3798,9265,9829,3949,55616,3800,23362,116986,2870,157,4734,9372,26056,4088,155382,6456,3480,644150,30845,11031,153,138429,5337,4233,23096,23111,3306,92421	FGFR4,ARAP2,DNM3,KIF5A,CYTH3,DNAJC6,LDLR,ASAP3,KIF5C,PSD3,AGAP2,GRK6,GRK3,NEDD4,ZFYVE9,RAB11FIP5,SMAD3,VPS37D,SH3GL2,IGF1R,WIPF3,EHD3,RAB31,ADRB1,PIP5KL1,PLD1,MET,IQSEC2,SPART,HSPA2,CHMP4C
hsa04919	Thyroid hormone signaling pathway	0.200179383731555	-1.60854139576751	116	15	0.0205479452054795	730	7161	5579,5208,6567,10000,4609,3690,652,481,5578,23236,9882,117247,5567,116931,478	PRKCB,PFKFB2,SLC16A2,AKT3,MYC,ITGB3,BMP4,ATP1B1,PRKCA,PLCB1,TBC1D4,SLC16A10,PRKACB,MED12L,ATP1A3
ko04137	Mitophagy - animal	0.200638694952589	-1.60624952598164	64	9	0.0123287671232877	730	7161	5071,468,665,664,84749,9474,5602,22800,23710	PRKN,ATF4,BNIP3L,BNIP3,USP30,ATG5,MAPK10,RRAS2,GABARAPL1
hsa04137	Mitophagy - animal	0.200638694952589	-1.60624952598164	64	9	0.0123287671232877	730	7161	5071,468,665,664,84749,9474,5602,22800,23710	PRKN,ATF4,BNIP3L,BNIP3,USP30,ATG5,MAPK10,RRAS2,GABARAPL1
hsa04964	Proximal tubule bicarbonate reclamation	0.201839170917064	-1.6002840822823	23	4	0.00547945205479452	730	7161	481,760,5106,478	ATP1B1,CA2,PCK2,ATP1A3
ko04964	Proximal tubule bicarbonate reclamation	0.201839170917064	-1.6002840822823	23	4	0.00547945205479452	730	7161	481,760,5106,478	ATP1B1,CA2,PCK2,ATP1A3
hsa04530	Tight junction	0.204750589704111	-1.58596267613535	170	21	0.0287671232876712	730	7161	5563,57530,154810,7846,11149,9693,7082,83700,4734,10207,153562,1740,8777,22989,5521,2017,8531,5602,58494,100506658,5567	PRKAA2,CGN,AMOTL1,TUBA1A,BVES,RAPGEF2,TJP1,JAM3,NEDD4,PATJ,MARVELD2,DLG2,MPDZ,MYH15,PPP2R2B,CTTN,YBX3,MAPK10,JAM2,OCLN,PRKACB
ko04530	Tight junction	0.204750589704111	-1.58596267613535	170	21	0.0287671232876712	730	7161	5563,57530,154810,7846,11149,9693,7082,83700,4734,10207,153562,1740,8777,22989,5521,2017,8531,5602,58494,100506658,5567	PRKAA2,CGN,AMOTL1,TUBA1A,BVES,RAPGEF2,TJP1,JAM3,NEDD4,PATJ,MARVELD2,DLG2,MPDZ,MYH15,PPP2R2B,CTTN,YBX3,MAPK10,JAM2,OCLN,PRKACB
hsa04924	Renin secretion	0.213431565504705	-1.54443903397392	65	9	0.0123287671232877	730	7161	5153,153,112,5593,3709,2977,23236,5567,2770	PDE1B,ADRB1,ADCY6,PRKG2,ITPR2,GUCY1A2,PLCB1,PRKACB,GNAI1
ko04924	Renin secretion	0.213431565504705	-1.54443903397392	65	9	0.0123287671232877	730	7161	5153,153,112,5593,3709,2977,23236,5567,2770	PDE1B,ADRB1,ADCY6,PRKG2,ITPR2,GUCY1A2,PLCB1,PRKACB,GNAI1
M00099	Sphingosine biosynthesis	0.218941206455083	-1.51895204888388	16	3	0.00410958904109589	730	7161	79603,10715,340485	CERS4,CERS1,ACER2
M00075	N-glycan biosynthesis, complex type	0.218941206455083	-1.51895204888388	16	3	0.00410958904109589	730	7161	146664,6480,11282	MGAT5B,ST6GAL1,MGAT4B
hsa_M00075	N-glycan biosynthesis, complex type	0.218941206455083	-1.51895204888388	16	3	0.00410958904109589	730	7161	146664,6480,11282	MGAT5B,ST6GAL1,MGAT4B
hsa_M00099	Sphingosine biosynthesis	0.218941206455083	-1.51895204888388	16	3	0.00410958904109589	730	7161	79603,10715,340485	CERS4,CERS1,ACER2
ko04072	Phospholipase D signaling pathway	0.220813418745277	-1.51043719312293	145	18	0.0246575342465753	730	7161	5321,9170,26052,56895,9265,11069,8612,107,5578,23236,8611,10000,112,5337,22800,6850,5159,9846	PLA2G4A,LPAR2,DNM3,AGPAT4,CYTH3,RAPGEF4,PLPP2,ADCY1,PRKCA,PLCB1,PLPP1,AKT3,ADCY6,PLD1,RRAS2,SYK,PDGFRB,GAB2
hsa04072	Phospholipase D signaling pathway	0.220813418745277	-1.51043719312293	145	18	0.0246575342465753	730	7161	5321,9170,26052,56895,9265,11069,8612,107,5578,23236,8611,10000,112,5337,22800,6850,5159,9846	PLA2G4A,LPAR2,DNM3,AGPAT4,CYTH3,RAPGEF4,PLPP2,ADCY1,PRKCA,PLCB1,PLPP1,AKT3,ADCY6,PLD1,RRAS2,SYK,PDGFRB,GAB2
ko05410	Hypertrophic cardiomyopathy (HCM)	0.221894426914936	-1.50555356465896	83	11	0.0150684931506849	730	7161	5563,3695,10368,783,3655,3673,3690,6262,7168,785,781	PRKAA2,ITGB7,CACNG3,CACNB2,ITGA6,ITGA2,ITGB3,RYR2,TPM1,CACNB4,CACNA2D1
hsa05410	Hypertrophic cardiomyopathy (HCM)	0.221894426914936	-1.50555356465896	83	11	0.0150684931506849	730	7161	5563,3695,10368,783,3655,3673,3690,6262,7168,785,781	PRKAA2,ITGB7,CACNG3,CACNB2,ITGA6,ITGA2,ITGB3,RYR2,TPM1,CACNB4,CACNA2D1
ko04062	Chemokine signaling pathway	0.227829991500898	-1.47915557947576	182	22	0.0301369863013699	730	7161	643,5058,10451,55970,5829,107,57580,6777,1147,2870,23236,1794,157,2770,3627,2268,5579,10000,59345,5580,112,5567	CXCR5,PAK1,VAV3,GNG12,PXN,ADCY1,PREX1,STAT5B,CHUK,GRK6,PLCB1,DOCK2,GRK3,GNAI1,CXCL10,FGR,PRKCB,AKT3,GNB4,PRKCD,ADCY6,PRKACB
hsa04062	Chemokine signaling pathway	0.227829991500898	-1.47915557947576	182	22	0.0301369863013699	730	7161	643,5058,10451,55970,5829,107,57580,6777,1147,2870,23236,1794,157,2770,3627,2268,5579,10000,59345,5580,112,5567	CXCR5,PAK1,VAV3,GNG12,PXN,ADCY1,PREX1,STAT5B,CHUK,GRK6,PLCB1,DOCK2,GRK3,GNAI1,CXCL10,FGR,PRKCB,AKT3,GNB4,PRKCD,ADCY6,PRKACB
ko00330	Arginine and proline metabolism	0.228282319711649	-1.47717217167063	49	7	0.00958904109589041	730	7161	4128,5033,217,2628,8974,4846,5831	MAOA,P4HA1,ALDH2,GATM,P4HA2,NOS3,PYCR1
hsa00330	Arginine and proline metabolism	0.228282319711649	-1.47717217167063	49	7	0.00958904109589041	730	7161	4128,5033,217,8974,2628,4846,5831	MAOA,P4HA1,ALDH2,P4HA2,GATM,NOS3,PYCR1
M00694	cGMP signaling	0.231812918107466	-1.46182462008892	9	2	0.00273972602739726	730	7161	2977,5592	GUCY1A2,PRKG1
M00131	Inositol phosphate metabolism, Ins(1,3,4,5)P4 => Ins(1,3,4)P3 => myo-inositol	0.231812918107466	-1.46182462008892	9	2	0.00273972602739726	730	7161	3628,8821	INPP1,INPP4B
hsa_M00135	GABA biosynthesis, eukaryotes, putrescine => GABA	0.231812918107466	-1.46182462008892	9	2	0.00273972602739726	730	7161	4128,217	MAOA,ALDH2
hsa_M00694	cGMP signaling	0.231812918107466	-1.46182462008892	9	2	0.00273972602739726	730	7161	2977,5592	GUCY1A2,PRKG1
hsa_M00131	Inositol phosphate metabolism, Ins(1,3,4,5)P4 => Ins(1,3,4)P3 => myo-inositol	0.231812918107466	-1.46182462008892	9	2	0.00273972602739726	730	7161	3628,8821	INPP1,INPP4B
M00135	GABA biosynthesis, eukaryotes, putrescine => GABA	0.231812918107466	-1.46182462008892	9	2	0.00273972602739726	730	7161	4128,217	MAOA,ALDH2
hsa05142	Chagas disease (American trypanosomiasis)	0.237235397102154	-1.43870239406227	102	13	0.0178082191780822	730	7161	4088,2775,10000,7132,107,1147,5603,5521,5602,23236,10333,7099,2770	SMAD3,GNAO1,AKT3,TNFRSF1A,ADCY1,CHUK,MAPK13,PPP2R2B,MAPK10,PLCB1,TLR6,TLR4,GNAI1
ko05142	Chagas disease (American trypanosomiasis)	0.237235397102154	-1.43870239406227	102	13	0.0178082191780822	730	7161	4088,2775,10000,7132,107,1147,5603,5521,5602,23236,10333,7099,2770	SMAD3,GNAO1,AKT3,TNFRSF1A,ADCY1,CHUK,MAPK13,PPP2R2B,MAPK10,PLCB1,TLR6,TLR4,GNAI1
hsa04910	Insulin signaling pathway	0.238829842278574	-1.43200393760578	138	17	0.0232876712328767	730	7161	5563,5509,10580,23433,3636,2194,5577,8660,10000,1978,6720,3099,3098,10891,5106,5602,5567	PRKAA2,PPP1R3D,SORBS1,RHOQ,INPPL1,FASN,PRKAR2B,IRS2,AKT3,EIF4EBP1,SREBF1,HK2,HK1,PPARGC1A,PCK2,MAPK10,PRKACB
ko04910	Insulin signaling pathway	0.238829842278574	-1.43200393760578	138	17	0.0232876712328767	730	7161	5563,5509,10580,23433,3636,2194,5577,8660,10000,1978,6720,3099,3098,10891,5106,5602,5567	PRKAA2,PPP1R3D,SORBS1,RHOQ,INPPL1,FASN,PRKAR2B,IRS2,AKT3,EIF4EBP1,SREBF1,HK2,HK1,PPARGC1A,PCK2,MAPK10,PRKACB
ko00010	Glycolysis / Gluconeogenesis	0.239935922687274	-1.42738338009102	67	9	0.0123287671232877	730	7161	217,2597,2026,230,226,3099,3098,5106,2023	ALDH2,GAPDH,ENO2,ALDOC,ALDOA,HK2,HK1,PCK2,ENO1
hsa00010	Glycolysis / Gluconeogenesis	0.239935922687274	-1.42738338009102	67	9	0.0123287671232877	730	7161	217,2597,2026,230,226,3099,3098,5106,2023	ALDH2,GAPDH,ENO2,ALDOC,ALDOA,HK2,HK1,PCK2,ENO1
hsa04720	Long-term potentiation	0.239935922687274	-1.42738338009102	67	9	0.0123287671232877	730	7161	468,6196,5579,107,2906,3709,5578,23236,5567	ATF4,RPS6KA2,PRKCB,ADCY1,GRIN2D,ITPR2,PRKCA,PLCB1,PRKACB
ko04720	Long-term potentiation	0.239935922687274	-1.42738338009102	67	9	0.0123287671232877	730	7161	468,6196,5579,107,2906,3709,5578,23236,5567	ATF4,RPS6KA2,PRKCB,ADCY1,GRIN2D,ITPR2,PRKCA,PLCB1,PRKACB
hsa00062	Fatty acid elongation	0.247005853776666	-1.39834324313432	25	4	0.00547945205479452	730	7161	6785,79993,83401,9200	ELOVL4,ELOVL7,ELOVL3,HACD1
ko00062	Fatty acid elongation	0.247005853776666	-1.39834324313432	25	4	0.00547945205479452	730	7161	6785,83401,79993,9200	ELOVL4,ELOVL3,ELOVL7,HACD1
hsa00910	Nitrogen metabolism	0.247177935801134	-1.3976468138501	17	3	0.00410958904109589	730	7161	760,767,377677	CA2,CA8,CA13
hsa00450	Selenocompound metabolism	0.247177935801134	-1.3976468138501	17	3	0.00410958904109589	730	7161	4141,1491,114112	MARS,CTH,TXNRD3
ko00910	Nitrogen metabolism	0.247177935801134	-1.3976468138501	17	3	0.00410958904109589	730	7161	760,767,377677	CA2,CA8,CA13
ko00450	Selenocompound metabolism	0.247177935801134	-1.3976468138501	17	3	0.00410958904109589	730	7161	4141,1491,114112	MARS,CTH,TXNRD3
hsa05146	Amoebiasis	0.247198712573565	-1.39756276144791	94	12	0.0164383561643836	730	7161	2335,1285,5579,1286,3912,107,10319,1287,5578,7099,23236,5567	FN1,COL4A3,PRKCB,COL4A4,LAMB1,ADCY1,LAMC3,COL4A5,PRKCA,TLR4,PLCB1,PRKACB
ko05146	Amoebiasis	0.247198712573565	-1.39756276144791	94	12	0.0164383561643836	730	7161	2335,1285,5579,1286,3912,107,10319,1287,5578,7099,23236,5567	FN1,COL4A3,PRKCB,COL4A4,LAMB1,ADCY1,LAMC3,COL4A5,PRKCA,TLR4,PLCB1,PRKACB
hsa05120	Epithelial cell signaling in Helicobacter pylori infection	0.253604528384129	-1.3719792001742	68	9	0.0123287671232877	730	7161	5058,90423,1147,7082,5603,4233,5602,58494,83700	PAK1,ATP6V1E2,CHUK,TJP1,MAPK13,MET,MAPK10,JAM2,JAM3
ko05120	Epithelial cell signaling in Helicobacter pylori infection	0.253604528384129	-1.3719792001742	68	9	0.0123287671232877	730	7161	5058,90423,1147,7082,5603,4233,5602,58494,83700	PAK1,ATP6V1E2,CHUK,TJP1,MAPK13,MET,MAPK10,JAM2,JAM3
hsa05218	Melanoma	0.267520953440735	-1.31855738509419	69	9	0.0123287671232877	730	7161	3082,8822,4233,3480,2258,10000,5159,2260,2257	HGF,FGF17,MET,IGF1R,FGF13,AKT3,PDGFRB,FGFR1,FGF12
hsa04115	p53 signaling pathway	0.267520953440735	-1.31855738509419	69	9	0.0123287671232877	730	7161	83667,5366,27113,55240,900,27244,64065,2810,3486	SESN2,PMAIP1,BBC3,STEAP3,CCNG1,SESN1,PERP,SFN,IGFBP3
ko05218	Melanoma	0.267520953440735	-1.31855738509419	69	9	0.0123287671232877	730	7161	3082,8822,4233,3480,2258,10000,5159,2260,2257	HGF,FGF17,MET,IGF1R,FGF13,AKT3,PDGFRB,FGFR1,FGF12
ko04115	p53 signaling pathway	0.267520953440735	-1.31855738509419	69	9	0.0123287671232877	730	7161	83667,5366,27113,55240,900,27244,64065,2810,3486	SESN2,PMAIP1,BBC3,STEAP3,CCNG1,SESN1,PERP,SFN,IGFBP3
hsa00072	Synthesis and degradation of ketone bodies	0.271406332311593	-1.30413819982853	10	2	0.00273972602739726	730	7161	3157,56898	HMGCS1,BDH2
ko00072	Synthesis and degradation of ketone bodies	0.271406332311593	-1.30413819982853	10	2	0.00273972602739726	730	7161	3157,56898	HMGCS1,BDH2
hsa_M00069	Glycosphingolipid biosynthesis, ganglio series, LacCer => GT3	0.275741084796401	-1.28829295211859	3	1	0.00136986301369863	730	7161	6489	ST8SIA1
hsa_M00082	Fatty acid biosynthesis, initiation	0.275741084796401	-1.28829295211859	3	1	0.00136986301369863	730	7161	2194	FASN
M00082	Fatty acid biosynthesis, initiation	0.275741084796401	-1.28829295211859	3	1	0.00136986301369863	730	7161	2194	FASN
M00069	Glycosphingolipid biosynthesis, ganglio series, LacCer => GT3	0.275741084796401	-1.28829295211859	3	1	0.00136986301369863	730	7161	6489	ST8SIA1
hsa05202	Transcriptional misregulation in cancer	0.279295968168122	-1.27548324162348	179	21	0.0287671232876712	730	7161	3695,860,5966,4291,6756,7468,1050,958,1051,3480,4609,8900,604,3248,4233,2115,4300,85414,1649,3486,4208	ITGB7,RUNX2,REL,MLF1,SSX1,NSD2,CEBPA,CD40,CEBPB,IGF1R,MYC,CCNA1,BCL6,HPGD,MET,ETV1,MLLT3,SLC45A3,DDIT3,IGFBP3,MEF2C
ko05202	Transcriptional misregulation in cancer	0.279295968168122	-1.27548324162348	179	21	0.0287671232876712	730	7161	3695,860,5966,4291,6756,7468,1050,958,1051,3480,4609,8900,604,3248,4233,2115,4300,85414,1649,3486,4208	ITGB7,RUNX2,REL,MLF1,SSX1,NSD2,CEBPA,CD40,CEBPB,IGF1R,MYC,CCNA1,BCL6,HPGD,MET,ETV1,MLLT3,SLC45A3,DDIT3,IGFBP3,MEF2C
hsa01521	EGFR tyrosine kinase inhibitor resistance	0.282605841865217	-1.26370213709393	79	10	0.0136986301369863	730	7161	3480,5579,10000,7039,1978,3082,2621,4233,5578,5159	IGF1R,PRKCB,AKT3,TGFA,EIF4EBP1,HGF,GAS6,MET,PRKCA,PDGFRB
ko01521	EGFR tyrosine kinase inhibitor resistance	0.282605841865217	-1.26370213709393	79	10	0.0136986301369863	730	7161	3480,5579,10000,7039,1978,3082,2621,4233,5578,5159	IGF1R,PRKCB,AKT3,TGFA,EIF4EBP1,HGF,GAS6,MET,PRKCA,PDGFRB
ko04973	Carbohydrate digestion and absorption	0.289211011684785	-1.24059871305732	44	6	0.00821917808219178	730	7161	3098,481,5579,10000,3099,478	HK1,ATP1B1,PRKCB,AKT3,HK2,ATP1A3
hsa04973	Carbohydrate digestion and absorption	0.289211011684785	-1.24059871305732	44	6	0.00821917808219178	730	7161	3098,481,5579,10000,3099,478	HK1,ATP1B1,PRKCB,AKT3,HK2,ATP1A3
ko00500	Starch and sucrose metabolism	0.30303805822703	-1.19389687665071	36	5	0.00684931506849315	730	7161	283209,5167,3098,178,3099	PGM2L1,ENPP1,HK1,AGL,HK2
hsa00500	Starch and sucrose metabolism	0.30303805822703	-1.19389687665071	36	5	0.00684931506849315	730	7161	283209,5167,3098,178,3099	PGM2L1,ENPP1,HK1,AGL,HK2
ko05231	Choline metabolism in cancer	0.307041027254088	-1.18077390105974	99	12	0.0164383561643836	730	7161	5321,10810,8611,5579,10000,1978,8612,5337,5578,5602,5881,5159	PLA2G4A,WASF3,PLPP1,PRKCB,AKT3,EIF4EBP1,PLPP2,PLD1,PRKCA,MAPK10,RAC3,PDGFRB
hsa05231	Choline metabolism in cancer	0.307041027254088	-1.18077390105974	99	12	0.0164383561643836	730	7161	5321,10810,8611,5579,10000,1978,8612,5337,5578,5602,5881,5159	PLA2G4A,WASF3,PLPP1,PRKCB,AKT3,EIF4EBP1,PLPP2,PLD1,PRKCA,MAPK10,RAC3,PDGFRB
hsa00480	Glutathione metabolism	0.309885060346586	-1.17155382333181	54	7	0.00958904109589041	730	7161	2947,9446,26873,2946,119391,2948,4259	GSTM3,GSTO1,OPLAH,GSTM2,GSTO2,GSTM4,MGST3
ko00480	Glutathione metabolism	0.309885060346586	-1.17155382333181	54	7	0.00958904109589041	730	7161	2947,26873,9446,2946,119391,2948,4259	GSTM3,OPLAH,GSTO1,GSTM2,GSTO2,GSTM4,MGST3
ko04930	Type II diabetes mellitus	0.32629680392477	-1.11994787032887	46	6	0.00821917808219178	730	7161	8660,3098,5602,777,5580,3099	IRS2,HK1,MAPK10,CACNA1E,PRKCD,HK2
hsa04930	Type II diabetes mellitus	0.32629680392477	-1.11994787032887	46	6	0.00821917808219178	730	7161	8660,3098,5602,777,5580,3099	IRS2,HK1,MAPK10,CACNA1E,PRKCD,HK2
hsa05131	Shigellosis	0.326388005651824	-1.11966840395763	64	8	0.010958904109589	730	7161	1793,5603,1147,2017,9474,5602,5217,8945	DOCK1,MAPK13,CHUK,CTTN,ATG5,MAPK10,PFN2,BTRC
hsa04210	Apoptosis	0.331101503128067	-1.10533029463837	138	16	0.0219178082191781	730	7161	468,7846,5783,1147,3709,8794,5366,10000,2081,1515,7132,27113,153090,8739,5602,1649	ATF4,TUBA1A,PTPN13,CHUK,ITPR2,TNFRSF10C,PMAIP1,AKT3,ERN1,CTSV,TNFRSF1A,BBC3,DAB2IP,HRK,MAPK10,DDIT3
ko04210	Apoptosis	0.331101503128067	-1.10533029463837	138	16	0.0219178082191781	730	7161	468,7846,5783,1147,3709,8794,5366,10000,2081,1515,7132,27113,153090,8739,5602,1649	ATF4,TUBA1A,PTPN13,CHUK,ITPR2,TNFRSF10C,PMAIP1,AKT3,ERN1,CTSV,TNFRSF1A,BBC3,DAB2IP,HRK,MAPK10,DDIT3
hsa04914	Progesterone-mediated oocyte maturation	0.334790551156726	-1.09425016311655	92	11	0.0150684931506849	730	7161	6196,3480,10000,8900,107,112,5603,5602,64506,5567,2770	RPS6KA2,IGF1R,AKT3,CCNA1,ADCY1,ADCY6,MAPK13,MAPK10,CPEB1,PRKACB,GNAI1
ko04914	Progesterone-mediated oocyte maturation	0.334790551156726	-1.09425016311655	92	11	0.0150684931506849	730	7161	6196,3480,10000,8900,107,112,5603,5602,64506,5567,2770	RPS6KA2,IGF1R,AKT3,CCNA1,ADCY1,ADCY6,MAPK13,MAPK10,CPEB1,PRKACB,GNAI1
M00359	Aminoacyl-tRNA biosynthesis, eukaryotes	0.344837595361505	-1.06468171086533	38	5	0.00684931506849315	730	7161	833,4141,2617,16,7453	CARS,MARS,GARS,AARS,WARS
hsa_M00677	Wnt signaling	0.344837595361505	-1.06468171086533	38	5	0.00684931506849315	730	7161	83439,7481,8322,8325,8321	TCF7L1,WNT11,FZD4,FZD8,FZD1
M00677	Wnt signaling	0.344837595361505	-1.06468171086533	38	5	0.00684931506849315	730	7161	83439,7481,8322,8325,8321	TCF7L1,WNT11,FZD4,FZD8,FZD1
hsa_M00359	Aminoacyl-tRNA biosynthesis, eukaryotes	0.344837595361505	-1.06468171086533	38	5	0.00684931506849315	730	7161	833,4141,2617,16,7453	CARS,MARS,GARS,AARS,WARS
hsa_M00027	GABA (gamma-Aminobutyrate) shunt	0.34960375706301	-1.05095488851076	4	1	0.00136986301369863	730	7161	18	ABAT
M00015	Proline biosynthesis, glutamate => proline	0.34960375706301	-1.05095488851076	4	1	0.00136986301369863	730	7161	5831	PYCR1
hsa_M00425	H/ACA ribonucleoprotein complex	0.34960375706301	-1.05095488851076	4	1	0.00136986301369863	730	7161	55651	NHP2
hsa_M00015	Proline biosynthesis, glutamate => proline	0.34960375706301	-1.05095488851076	4	1	0.00136986301369863	730	7161	5831	PYCR1
M00027	GABA (gamma-Aminobutyrate) shunt	0.34960375706301	-1.05095488851076	4	1	0.00136986301369863	730	7161	18	ABAT
M00425	H/ACA ribonucleoprotein complex	0.34960375706301	-1.05095488851076	4	1	0.00136986301369863	730	7161	55651	NHP2
M00094	Ceramide biosynthesis	0.34996027144993	-1.0499356410845	12	2	0.00273972602739726	730	7161	79603,10715	CERS4,CERS1
hsa_M00094	Ceramide biosynthesis	0.34996027144993	-1.0499356410845	12	2	0.00273972602739726	730	7161	79603,10715	CERS4,CERS1
hsa_M00049	Adenine ribonucleotide biosynthesis, IMP => ADP,ATP	0.36323030777401	-1.01271818922212	21	3	0.00410958904109589	730	7161	205,203,122622	AK4,AK1,ADSSL1
M00049	Adenine ribonucleotide biosynthesis, IMP => ADP,ATP	0.36323030777401	-1.01271818922212	21	3	0.00410958904109589	730	7161	205,203,122622	AK4,AK1,ADSSL1
hsa01212	Fatty acid metabolism	0.363964180785193	-1.01069982062371	48	6	0.00821917808219178	730	7161	3992,6319,2180,1962,9200,2194	FADS1,SCD,ACSL1,EHHADH,HACD1,FASN
ko01212	Fatty acid metabolism	0.363964180785193	-1.01069982062371	48	6	0.00821917808219178	730	7161	3992,6319,2180,1962,9200,2194	FADS1,SCD,ACSL1,EHHADH,HACD1,FASN
hsa05100	Bacterial invasion of epithelial cells	0.369901710870561	-0.994517954929875	76	9	0.0123287671232877	730	7161	26052,5829,2335,1793,2017,4233,55964,1496,26084	DNM3,PXN,FN1,DOCK1,CTTN,MET,SEPT3,CTNNA2,ARHGEF26
ko05100	Bacterial invasion of epithelial cells	0.369901710870561	-0.994517954929875	76	9	0.0123287671232877	730	7161	26052,5829,2335,1793,2017,4233,55964,1496,26084	DNM3,PXN,FN1,DOCK1,CTTN,MET,SEPT3,CTNNA2,ARHGEF26
hsa00564	Glycerophospholipid metabolism	0.374880362733533	-0.981148336624068	95	11	0.0150684931506849	730	7161	5321,8611,54947,56895,10400,8612,5337,64900,129642,64850,1040	PLA2G4A,PLPP1,LPCAT2,AGPAT4,PEMT,PLPP2,PLD1,LPIN3,MBOAT2,ETNPPL,CDS1
ko00564	Glycerophospholipid metabolism	0.374880362733533	-0.981148336624068	95	11	0.0150684931506849	730	7161	5321,8611,56895,10400,54947,8612,5337,64900,129642,64850,1040	PLA2G4A,PLPP1,AGPAT4,PEMT,LPCAT2,PLPP2,PLD1,LPIN3,MBOAT2,ETNPPL,CDS1
hsa05144	Malaria	0.38289653349854	-0.959990473821302	49	6	0.00821917808219178	730	7161	3082,4233,2995,958,7099,7060	HGF,MET,GYPC,CD40,TLR4,THBS4
ko00510	N-Glycan biosynthesis	0.38289653349854	-0.959990473821302	49	6	0.00821917808219178	730	7161	440138,146664,4245,6480,11282,144245	ALG11,MGAT5B,MGAT1,ST6GAL1,MGAT4B,ALG10B
hsa00510	N-Glycan biosynthesis	0.38289653349854	-0.959990473821302	49	6	0.00821917808219178	730	7161	440138,146664,4245,6480,11282,144245	ALG11,MGAT5B,MGAT1,ST6GAL1,MGAT4B,ALG10B
ko05144	Malaria	0.38289653349854	-0.959990473821302	49	6	0.00821917808219178	730	7161	3082,4233,2995,958,7099,7060	HGF,MET,GYPC,CD40,TLR4,THBS4
ko04020	Calcium signaling pathway	0.385900174612485	-0.952176557957493	181	20	0.0273972602739726	730	7161	91807,5153,777,107,6262,3709,5578,23236,90550,3363,5579,153,2906,5021,493,490,1131,5159,5567,4846	MYLK3,PDE1B,CACNA1E,ADCY1,RYR2,ITPR2,PRKCA,PLCB1,MCU,HTR7,PRKCB,ADRB1,GRIN2D,OXTR,ATP2B4,ATP2B1,CHRM3,PDGFRB,PRKACB,NOS3
hsa04020	Calcium signaling pathway	0.385900174612485	-0.952176557957493	181	20	0.0273972602739726	730	7161	91807,5153,777,107,6262,3709,5578,23236,90550,3363,5579,153,2906,5021,490,1131,493,5567,5159,4846	MYLK3,PDE1B,CACNA1E,ADCY1,RYR2,ITPR2,PRKCA,PLCB1,MCU,HTR7,PRKCB,ADRB1,GRIN2D,OXTR,ATP2B1,CHRM3,ATP2B4,PRKACB,PDGFRB,NOS3
ko05033	Nicotine addiction	0.386966311452345	-0.949417640252206	40	5	0.00684931506849315	730	7161	2566,8973,2906,2570,2561	GABRG2,CHRNA6,GRIN2D,GABRR2,GABRB2
hsa05033	Nicotine addiction	0.386966311452345	-0.949417640252206	40	5	0.00684931506849315	730	7161	2566,8973,2906,2570,2561	GABRG2,CHRNA6,GRIN2D,GABRR2,GABRB2
hsa05031	Amphetamine addiction	0.390320875892384	-0.940786119440426	68	8	0.010958904109589	730	7161	64764,468,5579,4128,2906,9586,5578,5567	CREB3L2,ATF4,PRKCB,MAOA,GRIN2D,CREB5,PRKCA,PRKACB
ko05031	Amphetamine addiction	0.390320875892384	-0.940786119440426	68	8	0.010958904109589	730	7161	64764,468,5579,4128,2906,9586,5578,5567	CREB3L2,ATF4,PRKCB,MAOA,GRIN2D,CREB5,PRKCA,PRKACB
hsa03010	Ribosome	0.391033573650026	-0.938961856570456	134	15	0.0205479452054795	730	7161	6224,6154,51187,6136,6158,6205,6144,29093,6124,6206,51121,23521,6228,6164,6207	RPS20,RPL26,RSL24D1,RPL12,RPL28,RPS11,RPL21,MRPL22,RPL4,RPS12,RPL26L1,RPL13A,RPS23,RPL34,RPS13
ko03010	Ribosome	0.391033573650026	-0.938961856570456	134	15	0.0205479452054795	730	7161	6224,6154,51187,6136,6158,6205,6144,29093,6124,6206,51121,23521,6228,6164,6207	RPS20,RPL26,RSL24D1,RPL12,RPL28,RPS11,RPL21,MRPL22,RPL4,RPS12,RPL26L1,RPL13A,RPS23,RPL34,RPS13
M00689	MAPK (p38) signaling	0.392119573514637	-0.936188451229118	22	3	0.00410958904109589	730	7161	5603,5608,84451	MAPK13,MAP2K6,MAP3K21
hsa_M00689	MAPK (p38) signaling	0.392119573514637	-0.936188451229118	22	3	0.00410958904109589	730	7161	5603,5608,84451	MAPK13,MAP2K6,MAP3K21
hsa05215	Prostate cancer	0.394038763839757	-0.931305989143633	87	10	0.0136986301369863	730	7161	64764,83439,468,3480,10000,7039,1147,9586,2260,5159	CREB3L2,TCF7L1,ATF4,IGF1R,AKT3,TGFA,CHUK,CREB5,FGFR1,PDGFRB
ko05215	Prostate cancer	0.394038763839757	-0.931305989143633	87	10	0.0136986301369863	730	7161	64764,83439,468,3480,10000,7039,1147,9586,2260,5159	CREB3L2,TCF7L1,ATF4,IGF1R,AKT3,TGFA,CHUK,CREB5,FGFR1,PDGFRB
ko00982	Drug metabolism - cytochrome P450	0.406425783759633	-0.900353940439934	69	8	0.010958904109589	730	7161	2946,119391,2329,2948,4259,2947,4128,9446	GSTM2,GSTO2,FMO4,GSTM4,MGST3,GSTM3,MAOA,GSTO1
hsa00982	Drug metabolism - cytochrome P450	0.406425783759633	-0.900353940439934	69	8	0.010958904109589	730	7161	2946,119391,2329,2948,4259,2947,4128,9446	GSTM2,GSTO2,FMO4,GSTM4,MGST3,GSTM3,MAOA,GSTO1
ko05210	Colorectal cancer	0.413286989860847	-0.88361303664163	60	7	0.00958904109589041	730	7161	4088,83439,5602,1630,10000,4609,5881	SMAD3,TCF7L1,MAPK10,DCC,AKT3,MYC,RAC3
hsa05210	Colorectal cancer	0.413286989860847	-0.88361303664163	60	7	0.00958904109589041	730	7161	4088,83439,5602,1630,10000,4609,5881	SMAD3,TCF7L1,MAPK10,DCC,AKT3,MYC,RAC3
ko04610	Complement and coagulation cascades	0.415135003193414	-0.879151502753113	79	9	0.0123287671232877	730	7161	1604,3075,720,1380,715,2161,5627,725,2152	CD55,CFH,C4A,CR2,C1R,F12,PROS1,C4BPB,F3
hsa04610	Complement and coagulation cascades	0.415135003193414	-0.879151502753113	79	9	0.0123287671232877	730	7161	1604,3075,720,1380,715,2161,5627,725,2152	CD55,CFH,C4A,CR2,C1R,F12,PROS1,C4BPB,F3
M00405	THC complex	0.415942901582367	-0.877207283952932	5	1	0.00136986301369863	730	7161	8563	THOC5
M00380	SCF-BTRC complex	0.415942901582367	-0.877207283952932	5	1	0.00136986301369863	730	7161	8945	BTRC
hsa_M00380	SCF-BTRC complex	0.415942901582367	-0.877207283952932	5	1	0.00136986301369863	730	7161	8945	BTRC
hsa_M00405	THC complex	0.415942901582367	-0.877207283952932	5	1	0.00136986301369863	730	7161	8563	THOC5
ko00515	Mannose type O-glycan biosynthesis	0.420661633904986	-0.86592648839644	23	3	0.00410958904109589	730	7161	146664,10690,9486	MGAT5B,FUT9,CHST10
hsa00515	Mannose type O-glycan biosynthesis	0.420661633904986	-0.86592648839644	23	3	0.00410958904109589	730	7161	146664,10690,9486	MGAT5B,FUT9,CHST10
ko01040	Biosynthesis of unsaturated fatty acids	0.420661633904986	-0.86592648839644	23	3	0.00410958904109589	730	7161	3992,6319,9200	FADS1,SCD,HACD1
hsa01040	Biosynthesis of unsaturated fatty acids	0.420661633904986	-0.86592648839644	23	3	0.00410958904109589	730	7161	3992,6319,9200	FADS1,SCD,HACD1
hsa04978	Mineral absorption	0.420733231659682	-0.865756300158317	51	6	0.00821917808219178	730	7161	30061,481,26872,490,475,478	SLC40A1,ATP1B1,STEAP1,ATP2B1,ATOX1,ATP1A3
ko04978	Mineral absorption	0.420733231659682	-0.865756300158317	51	6	0.00821917808219178	730	7161	30061,481,26872,490,475,478	SLC40A1,ATP1B1,STEAP1,ATP2B1,ATOX1,ATP1A3
M00055	N-glycan precursor biosynthesis	0.425431501482877	-0.854651327516966	14	2	0.00273972602739726	730	7161	440138,144245	ALG11,ALG10B
hsa_M00055	N-glycan precursor biosynthesis	0.425431501482877	-0.854651327516966	14	2	0.00273972602739726	730	7161	440138,144245	ALG11,ALG10B
hsa01100	Metabolic pathways	0.436924431649446	-0.827995024127158	1256	130	0.178082191780822	730	7161	349565,4598,2180,7368,10157,7358,445,18,146664,9486,23475,1595,1890,51166,4714,374378,2023,2731,2651,8612,5831,203,5167,10855,8974,226,8707,56898,5287,51084,84706,1962,6480,1573,284716,55301,1718,90423,114805,100526760,51477,22856,26227,122622,80055,26301,2589,6307,6489,178,4846,3156,337876,56901,4860,11282,2194,64409,256435,283358,23236,144193,26035,57494,3099,6713,5337,1717,79646,270,6296,5321,79695,11226,54947,64131,64900,83594,1592,1040,8611,3422,440,8564,230,2628,144245,1491,2597,8708,7390,4597,53354,48,64850,27010,6999,10400,8821,4128,440138,5033,113612,129642,5723,2026,645,875,3628,3157,10690,4245,85007,79603,5106,9331,217,123688,56895,55753,205,79623,2591,340485,138429,3098,10715,129607,9536,11285	NMNAT3,MVK,ACSL1,UGT8,AASS,UGDH,ASS1,ABAT,MGAT5B,CHST10,QPRT,CYP51A1,TYMP,AADAT,NDUFB8,GALNT18,ENO1,GLDC,GCNT2,PLPP2,PYCR1,AK1,ENPP1,HPSE,P4HA2,ALDOA,B3GALT2,BDH2,PIK3C2B,CRYL1,GPT2,EHHADH,ST6GAL1,CYP2J2,RIMKLA,OLAH,DHCR24,ATP6V1E2,GALNT13,ABHD14A-ACY1,ISYNA1,CHSY1,PHGDH,ADSSL1,PGAP1,GBGT1,GALNT1,MSMO1,ST8SIA1,AGL,NOS3,HMGCR,CHSY3,NDUFA4L2,PNP,MGAT4B,FASN,GALNT17,ST6GALNAC3,B4GALNT3,PLCB1,AMDHD1,GLCE,RIMKLB,HK2,SQLE,PLD1,DHCR7,PANK3,AMPD1,ACSM3,PLA2G4A,GALNT12,GALNT6,LPCAT2,XYLT1,LPIN3,NUDT12,CYP26A1,CDS1,PLPP1,IDI1,ASNS,KMO,ALDOC,GATM,ALG10B,CTH,GAPDH,B3GALT1,UROS,MVD,PANK1,ACO1,ETNPPL,TPK1,TDO2,PEMT,INPP4B,MAOA,ALG11,P4HA1,CYP2U1,MBOAT2,PSPH,ENO2,BLVRB,CBS,INPP1,HMGCS1,FUT9,MGAT1,PHYKPL,CERS4,PCK2,B4GALT6,ALDH2,HYKK,AGPAT4,OGDHL,AK4,GALNT14,GALNT3,ACER2,PIP5KL1,HK1,CERS1,CMPK2,PTGES,B4GALT7
ko04215	Apoptosis - multiple species	0.438126320136434	-0.825248008047616	33	4	0.00547945205479452	730	7161	27113,5602,5366,7132	BBC3,MAPK10,PMAIP1,TNFRSF1A
hsa04215	Apoptosis - multiple species	0.438126320136434	-0.825248008047616	33	4	0.00547945205479452	730	7161	27113,5602,5366,7132	BBC3,MAPK10,PMAIP1,TNFRSF1A
hsa05220	Chronic myeloid leukemia	0.438590312752335	-0.824189529990247	71	8	0.010958904109589	730	7161	4088,1147,1488,6777,10000,4609,9846,2122	SMAD3,CHUK,CTBP2,STAT5B,AKT3,MYC,GAB2,MECOM
ko05220	Chronic myeloid leukemia	0.438590312752335	-0.824189529990247	71	8	0.010958904109589	730	7161	4088,1147,1488,6777,10000,4609,9846,2122	SMAD3,CHUK,CTBP2,STAT5B,AKT3,MYC,GAB2,MECOM
hsa04380	Osteoclast differentiation	0.444341930744589	-0.81116089864615	129	14	0.0191780821917808	730	7161	5608,1435,10000,3690,7132,2274,10859,1147,5603,3937,5602,8792,6850,9846	MAP2K6,CSF1,AKT3,ITGB3,TNFRSF1A,FHL2,LILRB1,CHUK,MAPK13,LCP2,MAPK10,TNFRSF11A,SYK,GAB2
ko04380	Osteoclast differentiation	0.444341930744589	-0.81116089864615	129	14	0.0191780821917808	730	7161	5608,1435,10000,3690,7132,2274,10859,1147,5603,3937,5602,8792,6850,9846	MAP2K6,CSF1,AKT3,ITGB3,TNFRSF1A,FHL2,LILRB1,CHUK,MAPK13,LCP2,MAPK10,TNFRSF11A,SYK,GAB2
hsa00340	Histidine metabolism	0.448738142135233	-0.801315763739955	24	3	0.00410958904109589	730	7161	4128,217,144193	MAOA,ALDH2,AMDHD1
ko00340	Histidine metabolism	0.448738142135233	-0.801315763739955	24	3	0.00410958904109589	730	7161	4128,217,144193	MAOA,ALDH2,AMDHD1
ko03320	PPAR signaling pathway	0.454598523729449	-0.788340614974491	72	8	0.010958904109589	730	7161	10580,2180,1962,11001,2172,6319,5106,5360	SORBS1,ACSL1,EHHADH,SLC27A2,FABP6,SCD,PCK2,PLTP
hsa03320	PPAR signaling pathway	0.454598523729449	-0.788340614974491	72	8	0.010958904109589	730	7161	10580,2180,1962,11001,2172,6319,5106,5360	SORBS1,ACSL1,EHHADH,SLC27A2,FABP6,SCD,PCK2,PLTP
hsa00604	Glycosphingolipid biosynthesis - ganglio series	0.461430907380519	-0.773422949399	15	2	0.00273972602739726	730	7161	256435,6489	ST6GALNAC3,ST8SIA1
hsa_M00686	Toll-like receptor signaling	0.461430907380519	-0.773422949399	15	2	0.00273972602739726	730	7161	1147,7099	CHUK,TLR4
M00686	Toll-like receptor signaling	0.461430907380519	-0.773422949399	15	2	0.00273972602739726	730	7161	1147,7099	CHUK,TLR4
ko00604	Glycosphingolipid biosynthesis - ganglio series	0.461430907380519	-0.773422949399	15	2	0.00273972602739726	730	7161	256435,6489	ST6GALNAC3,ST8SIA1
ko04660	T cell receptor signaling pathway	0.469513940485451	-0.756057288579839	102	11	0.0150684931506849	730	7161	5058,5788,10451,57144,5777,10000,5603,1147,5588,3937,10125	PAK1,PTPRC,VAV3,PAK5,PTPN6,AKT3,MAPK13,CHUK,PRKCQ,LCP2,RASGRP1
hsa04660	T cell receptor signaling pathway	0.469513940485451	-0.756057288579839	102	11	0.0150684931506849	730	7161	5058,5788,10451,57144,5777,10000,5603,1147,5588,3937,10125	PAK1,PTPRC,VAV3,PAK5,PTPN6,AKT3,MAPK13,CHUK,PRKCQ,LCP2,RASGRP1
hsa00970	Aminoacyl-tRNA biosynthesis	0.470284089024211	-0.754418322148808	44	5	0.00684931506849315	730	7161	833,4141,2617,16,7453	CARS,MARS,GARS,AARS,WARS
ko00970	Aminoacyl-tRNA biosynthesis	0.470284089024211	-0.754418322148808	44	5	0.00684931506849315	730	7161	833,4141,2617,16,7453	CARS,MARS,GARS,AARS,WARS
M00013	Malonate semialdehyde pathway, propanoyl-CoA => acetyl-CoA	0.475523907991567	-0.743338118572836	6	1	0.00136986301369863	730	7161	1962	EHHADH
M00029	Urea cycle	0.475523907991567	-0.743338118572836	6	1	0.00136986301369863	730	7161	445	ASS1
hsa_M00013	Malonate semialdehyde pathway, propanoyl-CoA => acetyl-CoA	0.475523907991567	-0.743338118572836	6	1	0.00136986301369863	730	7161	1962	EHHADH
hsa_M00029	Urea cycle	0.475523907991567	-0.743338118572836	6	1	0.00136986301369863	730	7161	445	ASS1
ko05212	Pancreatic cancer	0.482007011393833	-0.729796618577101	64	7	0.00958904109589041	730	7161	4088,1147,5337,5602,10000,7039,5881	SMAD3,CHUK,PLD1,MAPK10,AKT3,TGFA,RAC3
hsa05212	Pancreatic cancer	0.482007011393833	-0.729796618577101	64	7	0.00958904109589041	730	7161	4088,1147,5337,5602,10000,7039,5881	SMAD3,CHUK,PLD1,MAPK10,AKT3,TGFA,RAC3
ko04260	Cardiac muscle contraction	0.486345701061403	-0.720835588892753	74	8	0.010958904109589	730	7161	6262,10368,481,7168,785,783,781,478	RYR2,CACNG3,ATP1B1,TPM1,CACNB4,CACNB2,CACNA2D1,ATP1A3
hsa04260	Cardiac muscle contraction	0.486345701061403	-0.720835588892753	74	8	0.010958904109589	730	7161	6262,10368,481,7168,785,783,781,478	RYR2,CACNG3,ATP1B1,TPM1,CACNB4,CACNB2,CACNA2D1,ATP1A3
ko05130	Pathogenic Escherichia coli infection	0.495157226877959	-0.70287993679071	55	6	0.00821917808219178	730	7161	10382,2017,7846,5578,7099,100506658	TUBB4A,CTTN,TUBA1A,PRKCA,TLR4,OCLN
hsa05130	Pathogenic Escherichia coli infection	0.495157226877959	-0.70287993679071	55	6	0.00821917808219178	730	7161	10382,2017,7846,5578,7099,100506658	TUBB4A,CTTN,TUBA1A,PRKCA,TLR4,OCLN
hsa04950	Maturity onset diabetes of the young	0.503101870109098	-0.686962604320042	26	3	0.00410958904109589	730	7161	4825,3174,168620	NKX6-1,HNF4G,BHLHA15
ko04950	Maturity onset diabetes of the young	0.503101870109098	-0.686962604320042	26	3	0.00410958904109589	730	7161	4825,3174,168620	NKX6-1,HNF4G,BHLHA15
ko05132	Salmonella infection	0.504807904555104	-0.683577309091868	85	9	0.0123287671232877	730	7161	29941,7082,5603,79659,5585,5602,5217,7099,1780	PKN3,TJP1,MAPK13,DYNC2H1,PKN1,MAPK10,PFN2,TLR4,DYNC1I1
hsa05132	Salmonella infection	0.504807904555104	-0.683577309091868	85	9	0.0123287671232877	730	7161	29941,7082,5603,79659,5585,5602,5217,7099,1780	PKN3,TJP1,MAPK13,DYNC2H1,PKN1,MAPK10,PFN2,TLR4,DYNC1I1
hsa05224	Breast cancer	0.505660278518814	-0.681890221501854	144	15	0.0205479452054795	730	7161	83439,3480,2258,8322,26508,10000,4609,8325,2257,4040,7481,8822,2260,8321,23462	TCF7L1,IGF1R,FGF13,FZD4,HEYL,AKT3,MYC,FZD8,FGF12,LRP6,WNT11,FGF17,FGFR1,FZD1,HEY1
ko05224	Breast cancer	0.505660278518814	-0.681890221501854	144	15	0.0205479452054795	730	7161	83439,3480,2258,8322,26508,10000,4609,8325,2257,4040,7481,8822,2260,8321,23462	TCF7L1,IGF1R,FGF13,FZD4,HEYL,AKT3,MYC,FZD8,FGF12,LRP6,WNT11,FGF17,FGFR1,FZD1,HEY1
hsa05161	Hepatitis B	0.505660278518814	-0.681890221501854	144	15	0.0205479452054795	730	7161	64764,4088,468,7098,5579,10000,6775,4609,8900,1147,6777,9586,5578,5602,7099	CREB3L2,SMAD3,ATF4,TLR3,PRKCB,AKT3,STAT4,MYC,CCNA1,CHUK,STAT5B,CREB5,PRKCA,MAPK10,TLR4
hsa04141	Protein processing in endoplasmic reticulum	0.520039934460416	-0.653849673316144	165	17	0.0232876712328767	730	7161	5071,468,9871,56605,5611,7466,7494,2081,80267,10960,821,5602,3306,10970,1649,9709,81567	PRKN,ATF4,SEC24D,ERO1B,DNAJC3,WFS1,XBP1,ERN1,EDEM3,LMAN2,CANX,MAPK10,HSPA2,CKAP4,DDIT3,HERPUD1,TXNDC5
ko04141	Protein processing in endoplasmic reticulum	0.520039934460416	-0.653849673316144	165	17	0.0232876712328767	730	7161	5071,468,9871,56605,5611,7466,7494,2081,80267,10960,821,5602,3306,10970,1649,9709,81567	PRKN,ATF4,SEC24D,ERO1B,DNAJC3,WFS1,XBP1,ERN1,EDEM3,LMAN2,CANX,MAPK10,HSPA2,CKAP4,DDIT3,HERPUD1,TXNDC5
ko04640	Hematopoietic cell lineage	0.521106529850075	-0.651800786249155	96	10	0.0136986301369863	730	7161	951,1604,1435,3655,3673,3690,1380,924,3581,4311	CD37,CD55,CSF1,ITGA6,ITGA2,ITGB3,CR2,CD7,IL9R,MME
hsa04640	Hematopoietic cell lineage	0.521106529850075	-0.651800786249155	96	10	0.0136986301369863	730	7161	951,1604,1435,3655,3673,3690,1380,924,3581,4311	CD37,CD55,CSF1,ITGA6,ITGA2,ITGB3,CR2,CD7,IL9R,MME
hsa_M00047	Creatine pathway	0.529034396757914	-0.636701827011011	7	1	0.00136986301369863	730	7161	2628	GATM
M00047	Creatine pathway	0.529034396757914	-0.636701827011011	7	1	0.00136986301369863	730	7161	2628	GATM
M00086	beta-Oxidation, acyl-CoA synthesis	0.529034396757914	-0.636701827011011	7	1	0.00136986301369863	730	7161	2180	ACSL1
hsa_M00086	beta-Oxidation, acyl-CoA synthesis	0.529034396757914	-0.636701827011011	7	1	0.00136986301369863	730	7161	2180	ACSL1
ko04672	Intestinal immune network for IgA production	0.530361607999455	-0.634196225838385	47	5	0.00684931506849315	730	7161	3695,958,608,3600,10673	ITGB7,CD40,TNFRSF17,IL15,TNFSF13B
hsa04672	Intestinal immune network for IgA production	0.530361607999455	-0.634196225838385	47	5	0.00684931506849315	730	7161	3695,958,608,3600,10673	ITGB7,CD40,TNFRSF17,IL15,TNFSF13B
hsa05223	Non-small cell lung cancer	0.548781259164465	-0.60005535190634	58	6	0.00821917808219178	730	7161	6777,2272,5578,5579,10000,7039	STAT5B,FHIT,PRKCA,PRKCB,AKT3,TGFA
ko05223	Non-small cell lung cancer	0.548781259164465	-0.60005535190634	58	6	0.00821917808219178	730	7161	6777,2272,5578,5579,10000,7039	STAT5B,FHIT,PRKCA,PRKCB,AKT3,TGFA
ko00561	Glycerolipid metabolism	0.5660837908591	-0.569013171348748	59	6	0.00821917808219178	730	7161	8611,217,64900,129642,56895,8612	PLPP1,ALDH2,LPIN3,MBOAT2,AGPAT4,PLPP2
hsa00561	Glycerolipid metabolism	0.5660837908591	-0.569013171348748	59	6	0.00821917808219178	730	7161	8611,217,64900,129642,56895,8612	PLPP1,ALDH2,LPIN3,MBOAT2,AGPAT4,PLPP2
hsa_M00680	TGF-beta signaling	0.577092111380592	-0.549753386773664	8	1	0.00136986301369863	730	7161	4088	SMAD3
hsa_M00010	Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate	0.577092111380592	-0.549753386773664	8	1	0.00136986301369863	730	7161	48	ACO1
hsa_M00409	ESCRT-I complex	0.577092111380592	-0.549753386773664	8	1	0.00136986301369863	730	7161	155382	VPS37D
M00680	TGF-beta signaling	0.577092111380592	-0.549753386773664	8	1	0.00136986301369863	730	7161	4088	SMAD3
M00409	ESCRT-I complex	0.577092111380592	-0.549753386773664	8	1	0.00136986301369863	730	7161	155382	VPS37D
M00010	Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate	0.577092111380592	-0.549753386773664	8	1	0.00136986301369863	730	7161	48	ACO1
hsa04622	RIG-I-like receptor signaling pathway	0.580095500752784	-0.544562532525744	70	7	0.00958904109589041	730	7161	54941,3627,1147,9755,5603,9474,5602	RNF125,CXCL10,CHUK,TBKBP1,MAPK13,ATG5,MAPK10
ko04622	RIG-I-like receptor signaling pathway	0.580095500752784	-0.544562532525744	70	7	0.00958904109589041	730	7161	54941,3627,1147,9755,5603,9474,5602	RNF125,CXCL10,CHUK,TBKBP1,MAPK13,ATG5,MAPK10
M00684	JAK-STAT signaling	0.591037503999108	-0.525875805046116	19	2	0.00273972602739726	730	7161	6777,6775	STAT5B,STAT4
hsa_M00684	JAK-STAT signaling	0.591037503999108	-0.525875805046116	19	2	0.00273972602739726	730	7161	6777,6775	STAT5B,STAT4
hsa00562	Inositol phosphate metabolism	0.595572630694758	-0.518231931721822	71	7	0.00958904109589041	730	7161	5287,138429,51477,3636,3628,23236,8821	PIK3C2B,PIP5KL1,ISYNA1,INPPL1,INPP1,PLCB1,INPP4B
ko00562	Inositol phosphate metabolism	0.595572630694758	-0.518231931721822	71	7	0.00958904109589041	730	7161	138429,5287,51477,3636,3628,23236,8821	PIP5KL1,PIK3C2B,ISYNA1,INPPL1,INPP1,PLCB1,INPP4B
ko04922	Glucagon signaling pathway	0.601002759203937	-0.509155753435943	102	10	0.0136986301369863	730	7161	64764,5563,468,10000,3709,9586,10891,5106,23236,5567	CREB3L2,PRKAA2,ATF4,AKT3,ITPR2,CREB5,PPARGC1A,PCK2,PLCB1,PRKACB
hsa04922	Glucagon signaling pathway	0.601002759203937	-0.509155753435943	102	10	0.0136986301369863	730	7161	64764,5563,468,10000,3709,9586,10891,5106,23236,5567	CREB3L2,PRKAA2,ATF4,AKT3,ITPR2,CREB5,PPARGC1A,PCK2,PLCB1,PRKACB
ko00020	Citrate cycle (TCA cycle)	0.602726788083862	-0.506291272685013	30	3	0.00410958904109589	730	7161	5106,55753,48	PCK2,OGDHL,ACO1
hsa00020	Citrate cycle (TCA cycle)	0.602726788083862	-0.506291272685013	30	3	0.00410958904109589	730	7161	5106,55753,48	PCK2,OGDHL,ACO1
hsa00670	One carbon pool by folate	0.619582858158593	-0.478708836802455	20	2	0.00273972602739726	730	7161	160428,10840	ALDH1L2,ALDH1L1
ko00670	One carbon pool by folate	0.619582858158593	-0.478708836802455	20	2	0.00273972602739726	730	7161	160428,10840	ALDH1L2,ALDH1L1
hsa_M00361	Nucleotide sugar biosynthesis, eukaryotes	0.620252010540344	-0.47762941491553	9	1	0.00136986301369863	730	7161	7358	UGDH
M00078	Heparan sulfate degradation	0.620252010540344	-0.47762941491553	9	1	0.00136986301369863	730	7161	10855	HPSE
hsa_M00078	Heparan sulfate degradation	0.620252010540344	-0.47762941491553	9	1	0.00136986301369863	730	7161	10855	HPSE
M00361	Nucleotide sugar biosynthesis, eukaryotes	0.620252010540344	-0.47762941491553	9	1	0.00136986301369863	730	7161	7358	UGDH
hsa05166	HTLV-I infection	0.622671836637608	-0.473735645944737	256	25	0.0342465753424658	730	7161	4487,468,3600,8322,8325,107,1147,6777,467,7481,958,821,4088,7015,4609,10000,7494,7132,112,83660,8829,22800,5567,5159,8321	MSX1,ATF4,IL15,FZD4,FZD8,ADCY1,CHUK,STAT5B,ATF3,WNT11,CD40,CANX,SMAD3,TERT,MYC,AKT3,XBP1,TNFRSF1A,ADCY6,TLN2,NRP1,RRAS2,PRKACB,PDGFRB,FZD1
ko05166	HTLV-I infection	0.622671836637608	-0.473735645944737	256	25	0.0342465753424658	730	7161	4487,468,3600,8322,8325,107,1147,6777,467,7481,958,821,4088,7015,4609,10000,7494,7132,112,83660,8829,22800,5567,5159,8321	MSX1,ATF4,IL15,FZD4,FZD8,ADCY1,CHUK,STAT5B,ATF3,WNT11,CD40,CANX,SMAD3,TERT,MYC,AKT3,XBP1,TNFRSF1A,ADCY6,TLN2,NRP1,RRAS2,PRKACB,PDGFRB,FZD1
ko04670	Leukocyte transendothelial migration	0.623063935115334	-0.473106140877026	114	11	0.0150684931506849	730	7161	10451,5829,5579,11069,5603,5578,58494,83700,1496,100506658,2770	VAV3,PXN,PRKCB,RAPGEF4,MAPK13,PRKCA,JAM2,JAM3,CTNNA2,OCLN,GNAI1
hsa04670	Leukocyte transendothelial migration	0.623063935115334	-0.473106140877026	114	11	0.0150684931506849	730	7161	10451,5829,5579,11069,5603,5578,58494,83700,1496,100506658,2770	VAV3,PXN,PRKCB,RAPGEF4,MAPK13,PRKCA,JAM2,JAM3,CTNNA2,OCLN,GNAI1
ko01523	Antifolate resistance	0.625475831276156	-0.469242588868592	31	3	0.00410958904109589	730	7161	1147,1244,10257	CHUK,ABCC2,ABCC4
ko00410	beta-Alanine metabolism	0.625475831276156	-0.469242588868592	31	3	0.00410958904109589	730	7161	217,18,1962	ALDH2,ABAT,EHHADH
hsa01523	Antifolate resistance	0.625475831276156	-0.469242588868592	31	3	0.00410958904109589	730	7161	1147,1244,10257	CHUK,ABCC2,ABCC4
hsa00410	beta-Alanine metabolism	0.625475831276156	-0.469242588868592	31	3	0.00410958904109589	730	7161	18,217,1962	ABAT,ALDH2,EHHADH
hsa00980	Metabolism of xenobiotics by cytochrome P450	0.625627309533053	-0.469000437358143	73	7	0.00958904109589041	730	7161	2947,9446,2946,119391,2948,4259,1545	GSTM3,GSTO1,GSTM2,GSTO2,GSTM4,MGST3,CYP1B1
ko00980	Metabolism of xenobiotics by cytochrome P450	0.625627309533053	-0.469000437358143	73	7	0.00958904109589041	730	7161	2947,9446,2946,119391,2948,4259,1545	GSTM3,GSTO1,GSTM2,GSTO2,GSTM4,MGST3,CYP1B1
ko04620	Toll-like receptor signaling pathway	0.626192146318661	-0.468098011978348	104	10	0.0136986301369863	730	7161	3627,7098,5608,10000,5603,1147,958,5602,7099,10333	CXCL10,TLR3,MAP2K6,AKT3,MAPK13,CHUK,CD40,MAPK10,TLR4,TLR6
hsa04620	Toll-like receptor signaling pathway	0.626192146318661	-0.468098011978348	104	10	0.0136986301369863	730	7161	3627,7098,5608,10000,5603,1147,958,5602,7099,10333	CXCL10,TLR3,MAP2K6,AKT3,MAPK13,CHUK,CD40,MAPK10,TLR4,TLR6
ko04932	Non-alcoholic fatty liver disease (NAFLD)	0.626887431270566	-0.466988289921278	145	14	0.0191780821917808	730	7161	5563,8660,56901,468,10000,7494,2081,7132,6720,4714,1050,5602,3953,1649	PRKAA2,IRS2,NDUFA4L2,ATF4,AKT3,XBP1,ERN1,TNFRSF1A,SREBF1,NDUFB8,CEBPA,MAPK10,LEPR,DDIT3
hsa04932	Non-alcoholic fatty liver disease (NAFLD)	0.626887431270566	-0.466988289921278	145	14	0.0191780821917808	730	7161	5563,8660,56901,468,10000,7494,2081,7132,6720,4714,1050,5602,3953,1649	PRKAA2,IRS2,NDUFA4L2,ATF4,AKT3,XBP1,ERN1,TNFRSF1A,SREBF1,NDUFB8,CEBPA,MAPK10,LEPR,DDIT3
hsa04064	NF-kappa B signaling pathway	0.629946982393262	-0.462119618069113	94	9	0.0123287671232877	730	7161	5579,7132,10673,1147,5588,958,7099,8792,6850	PRKCB,TNFRSF1A,TNFSF13B,CHUK,PRKCQ,CD40,TLR4,TNFRSF11A,SYK
ko04064	NF-kappa B signaling pathway	0.629946982393262	-0.462119618069113	94	9	0.0123287671232877	730	7161	5579,7132,10673,1147,5588,958,7099,8792,6850	PRKCB,TNFRSF1A,TNFSF13B,CHUK,PRKCQ,CD40,TLR4,TNFRSF11A,SYK
hsa_M00688	MAPK (JNK) signaling	0.646567337149979	-0.436077929736314	21	2	0.00273972602739726	730	7161	5602,84451	MAPK10,MAP3K21
M00688	MAPK (JNK) signaling	0.646567337149979	-0.436077929736314	21	2	0.00273972602739726	730	7161	5602,84451	MAPK10,MAP3K21
ko05211	Renal cell carcinoma	0.647357763874525	-0.434856179231218	64	6	0.00821917808219178	730	7161	5058,3082,4233,57144,10000,7039	PAK1,HGF,MET,PAK5,AKT3,TGFA
hsa05214	Glioma	0.647357763874525	-0.434856179231218	64	6	0.00821917808219178	730	7161	3480,5578,5579,10000,7039,5159	IGF1R,PRKCA,PRKCB,AKT3,TGFA,PDGFRB
ko05214	Glioma	0.647357763874525	-0.434856179231218	64	6	0.00821917808219178	730	7161	3480,5578,5579,10000,7039,5159	IGF1R,PRKCA,PRKCB,AKT3,TGFA,PDGFRB
hsa05211	Renal cell carcinoma	0.647357763874525	-0.434856179231218	64	6	0.00821917808219178	730	7161	5058,3082,4233,57144,10000,7039	PAK1,HGF,MET,PAK5,AKT3,TGFA
hsa_M00693	Cell cycle - G2/M transition	0.659012641452276	-0.417012561883229	10	1	0.00136986301369863	730	7161	8900	CCNA1
hsa_M00035	Methionine degradation	0.659012641452276	-0.417012561883229	10	1	0.00136986301369863	730	7161	875	CBS
M00059	Glycosaminoglycan biosynthesis, heparan sulfate backbone	0.659012641452276	-0.417012561883229	10	1	0.00136986301369863	730	7161	26035	GLCE
hsa_M00059	Glycosaminoglycan biosynthesis, heparan sulfate backbone	0.659012641452276	-0.417012561883229	10	1	0.00136986301369863	730	7161	26035	GLCE
M00693	Cell cycle - G2/M transition	0.659012641452276	-0.417012561883229	10	1	0.00136986301369863	730	7161	8900	CCNA1
M00035	Methionine degradation	0.659012641452276	-0.417012561883229	10	1	0.00136986301369863	730	7161	875	CBS
hsa04070	Phosphatidylinositol signaling system	0.667701882672317	-0.403913488484252	97	9	0.0123287671232877	730	7161	3636,5579,8821,5287,3709,5578,23236,3628,1040	INPPL1,PRKCB,INPP4B,PIK3C2B,ITPR2,PRKCA,PLCB1,INPP1,CDS1
ko04070	Phosphatidylinositol signaling system	0.667701882672317	-0.403913488484252	97	9	0.0123287671232877	730	7161	3636,5579,8821,5287,3709,5578,23236,3628,1040	INPPL1,PRKCB,INPP4B,PIK3C2B,ITPR2,PRKCA,PLCB1,INPP1,CDS1
ko05133	Pertussis	0.668279093555976	-0.403049387977066	76	7	0.00958904109589041	730	7161	715,5603,5602,7099,720,725,2770	C1R,MAPK13,MAPK10,TLR4,C4A,C4BPB,GNAI1
hsa05133	Pertussis	0.668279093555976	-0.403049387977066	76	7	0.00958904109589041	730	7161	715,5603,5602,7099,720,725,2770	C1R,MAPK13,MAPK10,TLR4,C4A,C4BPB,GNAI1
hsa02010	ABC transporters	0.669564238878718	-0.401128167925536	44	4	0.00547945205479452	730	7161	1244,10257,23461,9619	ABCC2,ABCC4,ABCA5,ABCG1
ko02010	ABC transporters	0.669564238878718	-0.401128167925536	44	4	0.00547945205479452	730	7161	1244,10257,23461,9619	ABCC2,ABCC4,ABCA5,ABCG1
hsa_M00130	Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4	0.672012113518583	-0.397478912552135	22	2	0.00273972602739726	730	7161	138429,23236	PIP5KL1,PLCB1
M00009	Citrate cycle (TCA cycle, Krebs cycle)	0.672012113518583	-0.397478912552135	22	2	0.00273972602739726	730	7161	55753,48	OGDHL,ACO1
M00130	Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4	0.672012113518583	-0.397478912552135	22	2	0.00273972602739726	730	7161	138429,23236	PIP5KL1,PLCB1
hsa_M00009	Citrate cycle (TCA cycle, Krebs cycle)	0.672012113518583	-0.397478912552135	22	2	0.00273972602739726	730	7161	55753,48	OGDHL,ACO1
ko05143	African trypanosomiasis	0.688230211248392	-0.373631887645362	34	3	0.00410958904109589	730	7161	5578,5579,23236	PRKCA,PRKCB,PLCB1
hsa05143	African trypanosomiasis	0.688230211248392	-0.373631887645362	34	3	0.00410958904109589	730	7161	5578,5579,23236	PRKCA,PRKCB,PLCB1
hsa_M00678	Hedgehog signaling	0.693821866983563	-0.365540027238399	11	1	0.00136986301369863	730	7161	2735	GLI1
M00404	COPII complex	0.693821866983563	-0.365540027238399	11	1	0.00136986301369863	730	7161	9871	SEC24D
hsa_M00404	COPII complex	0.693821866983563	-0.365540027238399	11	1	0.00136986301369863	730	7161	9871	SEC24D
M00678	Hedgehog signaling	0.693821866983563	-0.365540027238399	11	1	0.00136986301369863	730	7161	2735	GLI1
hsa04614	Renin-angiotensin system	0.695950254430044	-0.362477094722124	23	2	0.00273972602739726	730	7161	5547,4311	PRCP,MME
ko04614	Renin-angiotensin system	0.695950254430044	-0.362477094722124	23	2	0.00273972602739726	730	7161	5547,4311	PRCP,MME
ko04145	Phagosome	0.696881695621397	-0.361139616313232	152	14	0.0191780821917808	730	7161	10382,9902,7846,7060,3673,3690,4481,90423,715,79659,821,1780,10333,7099	TUBB4A,MRC2,TUBA1A,THBS4,ITGA2,ITGB3,MSR1,ATP6V1E2,C1R,DYNC2H1,CANX,DYNC1I1,TLR6,TLR4
hsa04145	Phagosome	0.696881695621397	-0.361139616313232	152	14	0.0191780821917808	730	7161	10382,9902,7846,7060,3673,3690,4481,90423,715,79659,821,1780,10333,7099	TUBB4A,MRC2,TUBA1A,THBS4,ITGA2,ITGB3,MSR1,ATP6V1E2,C1R,DYNC2H1,CANX,DYNC1I1,TLR6,TLR4
ko05020	Prion diseases	0.707309892630199	-0.346286388568048	35	3	0.00410958904109589	730	7161	4684,4685,5567	NCAM1,NCAM2,PRKACB
hsa05020	Prion diseases	0.707309892630199	-0.346286388568048	35	3	0.00410958904109589	730	7161	4684,4685,5567	NCAM1,NCAM2,PRKACB
hsa04977	Vitamin digestion and absorption	0.71842408281977	-0.330695239699998	24	2	0.00273972602739726	730	7161	9227,10560	LRAT,SLC19A2
ko04977	Vitamin digestion and absorption	0.71842408281977	-0.330695239699998	24	2	0.00273972602739726	730	7161	9227,10560	LRAT,SLC19A2
M00087	beta-Oxidation	0.725082012038024	-0.321470510472606	12	1	0.00136986301369863	730	7161	1962	EHHADH
hsa_M00052	Pyrimidine ribonucleotide biosynthesis, UMP => UDP/UTP,CDP/CTP	0.725082012038024	-0.321470510472606	12	1	0.00136986301369863	730	7161	129607	CMPK2
M00412	ESCRT-III complex	0.725082012038024	-0.321470510472606	12	1	0.00136986301369863	730	7161	92421	CHMP4C
M00052	Pyrimidine ribonucleotide biosynthesis, UMP => UDP/UTP,CDP/CTP	0.725082012038024	-0.321470510472606	12	1	0.00136986301369863	730	7161	129607	CMPK2
hsa_M00087	beta-Oxidation	0.725082012038024	-0.321470510472606	12	1	0.00136986301369863	730	7161	1962	EHHADH
hsa_M00412	ESCRT-III complex	0.725082012038024	-0.321470510472606	12	1	0.00136986301369863	730	7161	92421	CHMP4C
hsa04917	Prolactin signaling pathway	0.731681589687996	-0.312409846420046	70	6	0.00821917808219178	730	7161	6777,5603,1447,5602,8792,10000	STAT5B,MAPK13,CSN2,MAPK10,TNFRSF11A,AKT3
ko04917	Prolactin signaling pathway	0.731681589687996	-0.312409846420046	70	6	0.00821917808219178	730	7161	6777,5603,1447,5602,8792,10000	STAT5B,MAPK13,CSN2,MAPK10,TNFRSF11A,AKT3
hsa00280	Valine, leucine and isoleucine degradation	0.735432852356578	-0.307296038340697	48	4	0.00547945205479452	730	7161	18,217,3157,1962	ABAT,ALDH2,HMGCS1,EHHADH
ko00520	Amino sugar and nucleotide sugar metabolism	0.735432852356578	-0.307296038340697	48	4	0.00547945205479452	730	7161	3098,51700,7358,3099	HK1,CYB5R2,UGDH,HK2
hsa00520	Amino sugar and nucleotide sugar metabolism	0.735432852356578	-0.307296038340697	48	4	0.00547945205479452	730	7161	3098,51700,7358,3099	HK1,CYB5R2,UGDH,HK2
ko00280	Valine, leucine and isoleucine degradation	0.735432852356578	-0.307296038340697	48	4	0.00547945205479452	730	7161	217,3157,18,1962	ALDH2,HMGCS1,ABAT,EHHADH
hsa00563	Glycosylphosphatidylinositol (GPI)-anchor biosynthesis	0.739482951712515	-0.30180405090025	25	2	0.00273972602739726	730	7161	80055,2822	PGAP1,GPLD1
ko00563	Glycosylphosphatidylinositol (GPI)-anchor biosynthesis	0.739482951712515	-0.30180405090025	25	2	0.00273972602739726	730	7161	80055,2822	PGAP1,GPLD1
ko04742	Taste transduction	0.744077364161265	-0.295610265467294	82	7	0.00958904109589041	730	7161	112,5028,6326,5153,5567,6328,1131	ADCY6,P2RY1,SCN2A,PDE1B,PRKACB,SCN3A,CHRM3
hsa05204	Chemical carcinogenesis	0.744077364161265	-0.295610265467294	82	7	0.00958904109589041	730	7161	2947,9446,2946,119391,4259,2948,1545	GSTM3,GSTO1,GSTM2,GSTO2,MGST3,GSTM4,CYP1B1
hsa04742	Taste transduction	0.744077364161265	-0.295610265467294	82	7	0.00958904109589041	730	7161	112,5028,6326,5153,5567,6328,1131	ADCY6,P2RY1,SCN2A,PDE1B,PRKACB,SCN3A,CHRM3
ko05204	Chemical carcinogenesis	0.744077364161265	-0.295610265467294	82	7	0.00958904109589041	730	7161	2947,9446,2946,119391,4259,2948,1545	GSTM3,GSTO1,GSTM2,GSTO2,MGST3,GSTM4,CYP1B1
M00403	HRD1/SEL1 ERAD complex	0.753154488071058	-0.283484908784404	13	1	0.00136986301369863	730	7161	9709	HERPUD1
hsa_M00403	HRD1/SEL1 ERAD complex	0.753154488071058	-0.283484908784404	13	1	0.00136986301369863	730	7161	9709	HERPUD1
hsa_M00676	PI3K-Akt signaling	0.753154488071058	-0.283484908784404	13	1	0.00136986301369863	730	7161	10000	AKT3
M00676	PI3K-Akt signaling	0.753154488071058	-0.283484908784404	13	1	0.00136986301369863	730	7161	10000	AKT3
hsa04146	Peroxisome	0.755435507414144	-0.28046086502406	83	7	0.00958904109589041	730	7161	51555,2180,4598,55711,1962,11001,83594	PEX5L,ACSL1,MVK,FAR2,EHHADH,SLC27A2,NUDT12
ko04146	Peroxisome	0.755435507414144	-0.28046086502406	83	7	0.00958904109589041	730	7161	51555,2180,4598,55711,1962,11001,83594	PEX5L,ACSL1,MVK,FAR2,EHHADH,SLC27A2,NUDT12
hsa05213	Endometrial cancer	0.764435107385168	-0.26861813964194	50	4	0.00547945205479452	730	7161	83439,10000,4609,1496	TCF7L1,AKT3,MYC,CTNNA2
ko05213	Endometrial cancer	0.764435107385168	-0.26861813964194	50	4	0.00547945205479452	730	7161	83439,10000,4609,1496	TCF7L1,AKT3,MYC,CTNNA2
hsa01522	Endocrine resistance	0.765972875861534	-0.266608519970934	95	8	0.010958904109589	730	7161	3480,10000,638,107,112,5603,5602,5567	IGF1R,AKT3,BIK,ADCY1,ADCY6,MAPK13,MAPK10,PRKACB
ko01522	Endocrine resistance	0.765972875861534	-0.266608519970934	95	8	0.010958904109589	730	7161	3480,10000,638,107,112,5603,5602,5567	IGF1R,AKT3,BIK,ADCY1,ADCY6,MAPK13,MAPK10,PRKACB
ko00620	Pyruvate metabolism	0.774704172906519	-0.25527403487819	39	3	0.00410958904109589	730	7161	217,5106,197257	ALDH2,PCK2,LDHD
hsa00620	Pyruvate metabolism	0.774704172906519	-0.25527403487819	39	3	0.00410958904109589	730	7161	217,5106,197257	ALDH2,PCK2,LDHD
ko04659	Th17 cell differentiation	0.775896814117921	-0.253735739137936	107	9	0.0123287671232877	730	7161	4088,53342,2625,5603,6777,1147,5588,5602,3556	SMAD3,IL17D,GATA3,MAPK13,STAT5B,CHUK,PRKCQ,MAPK10,IL1RAP
hsa04659	Th17 cell differentiation	0.775896814117921	-0.253735739137936	107	9	0.0123287671232877	730	7161	4088,53342,2625,5603,6777,1147,5588,5602,3556	SMAD3,IL17D,GATA3,MAPK13,STAT5B,CHUK,PRKCQ,MAPK10,IL1RAP
hsa_M00014	Glucuronate pathway (uronate pathway)	0.777577466445347	-0.251572004592533	27	2	0.00273972602739726	730	7161	7358,51084	UGDH,CRYL1
hsa00053	Ascorbate and aldarate metabolism	0.777577466445347	-0.251572004592533	27	2	0.00273972602739726	730	7161	217,7358	ALDH2,UGDH
ko00053	Ascorbate and aldarate metabolism	0.777577466445347	-0.251572004592533	27	2	0.00273972602739726	730	7161	217,7358	ALDH2,UGDH
ko04966	Collecting duct acid secretion	0.777577466445347	-0.251572004592533	27	2	0.00273972602739726	730	7161	90423,760	ATP6V1E2,CA2
M00014	Glucuronate pathway (uronate pathway)	0.777577466445347	-0.251572004592533	27	2	0.00273972602739726	730	7161	7358,51084	UGDH,CRYL1
hsa04966	Collecting duct acid secretion	0.777577466445347	-0.251572004592533	27	2	0.00273972602739726	730	7161	90423,760	ATP6V1E2,CA2
hsa05014	Amyotrophic lateral sclerosis (ALS)	0.777978715302161	-0.251056113401432	51	4	0.00547945205479452	730	7161	2906,5603,5608,7132	GRIN2D,MAPK13,MAP2K6,TNFRSF1A
ko05110	Vibrio cholerae infection	0.777978715302161	-0.251056113401432	51	4	0.00547945205479452	730	7161	90423,7082,5578,5567	ATP6V1E2,TJP1,PRKCA,PRKACB
ko05014	Amyotrophic lateral sclerosis (ALS)	0.777978715302161	-0.251056113401432	51	4	0.00547945205479452	730	7161	2906,5603,5608,7132	GRIN2D,MAPK13,MAP2K6,TNFRSF1A
hsa05110	Vibrio cholerae infection	0.777978715302161	-0.251056113401432	51	4	0.00547945205479452	730	7161	90423,7082,5578,5567	ATP6V1E2,TJP1,PRKCA,PRKACB
hsa_M00147	NADH dehydrogenase (ubiquinone) 1 beta subcomplex	0.778363948580328	-0.250561063956378	14	1	0.00136986301369863	730	7161	4714	NDUFB8
hsa_M00353	Spliceosome, Prp19/CDC5L complex	0.778363948580328	-0.250561063956378	14	1	0.00136986301369863	730	7161	3306	HSPA2
M00011	Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate	0.778363948580328	-0.250561063956378	14	1	0.00136986301369863	730	7161	55753	OGDHL
M00353	Spliceosome, Prp19/CDC5L complex	0.778363948580328	-0.250561063956378	14	1	0.00136986301369863	730	7161	3306	HSPA2
M00147	NADH dehydrogenase (ubiquinone) 1 beta subcomplex	0.778363948580328	-0.250561063956378	14	1	0.00136986301369863	730	7161	4714	NDUFB8
hsa_M00011	Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate	0.778363948580328	-0.250561063956378	14	1	0.00136986301369863	730	7161	55753	OGDHL
ko04721	Synaptic vesicle cycle	0.783622463726556	-0.243827925984014	63	5	0.00684931506849315	730	7161	90423,26052,6616,10497,6812	ATP6V1E2,DNM3,SNAP25,UNC13B,STXBP1
hsa04721	Synaptic vesicle cycle	0.783622463726556	-0.243827925984014	63	5	0.00684931506849315	730	7161	90423,26052,6616,10497,6812	ATP6V1E2,DNM3,SNAP25,UNC13B,STXBP1
ko00230	Purine metabolism	0.784082244714527	-0.243241360161155	173	15	0.0205479452054795	730	7161	953,203,5167,4860,5153,10846,107,205,112,5151,2272,5144,2977,122622,270	ENTPD1,AK1,ENPP1,PNP,PDE1B,PDE10A,ADCY1,AK4,ADCY6,PDE8A,FHIT,PDE4D,GUCY1A2,ADSSL1,AMPD1
hsa00230	Purine metabolism	0.784082244714527	-0.243241360161155	173	15	0.0205479452054795	730	7161	953,203,5167,4860,5153,10846,107,112,205,5151,2272,5144,2977,122622,270	ENTPD1,AK1,ENPP1,PNP,PDE1B,PDE10A,ADCY1,ADCY6,AK4,PDE8A,FHIT,PDE4D,GUCY1A2,ADSSL1,AMPD1
ko04722	Neurotrophin signaling pathway	0.785253758520628	-0.2417483541748	119	10	0.0136986301369863	730	7161	9261,627,468,6196,27018,10000,5580,5603,4916,5602	MAPKAPK2,BDNF,ATF4,RPS6KA2,BEX3,AKT3,PRKCD,MAPK13,NTRK3,MAPK10
hsa04722	Neurotrophin signaling pathway	0.785253758520628	-0.2417483541748	119	10	0.0136986301369863	730	7161	9261,627,468,6196,27018,10000,5580,5603,4916,5602	MAPKAPK2,BDNF,ATF4,RPS6KA2,BEX3,AKT3,PRKCD,MAPK13,NTRK3,MAPK10
ko04320	Dorso-ventral axis formation	0.794731640043103	-0.229750781008113	28	2	0.00273972602739726	730	7161	56907,64506	SPIRE1,CPEB1
hsa04320	Dorso-ventral axis formation	0.794731640043103	-0.229750781008113	28	2	0.00273972602739726	730	7161	56907,64506	SPIRE1,CPEB1
hsa00630	Glyoxylate and dicarboxylate metabolism	0.794731640043103	-0.229750781008113	28	2	0.00273972602739726	730	7161	48,2731	ACO1,GLDC
ko00630	Glyoxylate and dicarboxylate metabolism	0.794731640043103	-0.229750781008113	28	2	0.00273972602739726	730	7161	48,2731	ACO1,GLDC
hsa_M00146	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex	0.801002022952493	-0.221891806383268	15	1	0.00136986301369863	730	7161	56901	NDUFA4L2
M00146	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex	0.801002022952493	-0.221891806383268	15	1	0.00136986301369863	730	7161	56901	NDUFA4L2
hsa04650	Natural killer cell mediated cytotoxicity	0.802089675548917	-0.220534862467543	132	11	0.0150684931506849	730	7161	5058,10451,6452,5579,5777,8794,5578,3937,6850,5881,80329	PAK1,VAV3,SH3BP2,PRKCB,PTPN6,TNFRSF10C,PRKCA,LCP2,SYK,RAC3,ULBP1
ko04650	Natural killer cell mediated cytotoxicity	0.802089675548917	-0.220534862467543	132	11	0.0150684931506849	730	7161	5058,10451,6452,5579,5777,8794,5578,3937,6850,5881,80329	PAK1,VAV3,SH3BP2,PRKCB,PTPN6,TNFRSF10C,PRKCA,LCP2,SYK,RAC3,ULBP1
ko05321	Inflammatory bowel disease (IBD)	0.806229706301121	-0.215386581668166	65	5	0.00684931506849315	730	7161	2625,4088,7099,8809,6775	GATA3,SMAD3,TLR4,IL18R1,STAT4
hsa05321	Inflammatory bowel disease (IBD)	0.806229706301121	-0.215386581668166	65	5	0.00684931506849315	730	7161	2625,4088,7099,8809,6775	GATA3,SMAD3,TLR4,IL18R1,STAT4
hsa00591	Linoleic acid metabolism	0.810705540663986	-0.20985037259221	29	2	0.00273972602739726	730	7161	5321,1573	PLA2G4A,CYP2J2
ko05216	Thyroid cancer	0.810705540663986	-0.20985037259221	29	2	0.00273972602739726	730	7161	83439,4609	TCF7L1,MYC
ko00591	Linoleic acid metabolism	0.810705540663986	-0.20985037259221	29	2	0.00273972602739726	730	7161	5321,1573	PLA2G4A,CYP2J2
hsa05216	Thyroid cancer	0.810705540663986	-0.20985037259221	29	2	0.00273972602739726	730	7161	83439,4609	TCF7L1,MYC
ko00030	Pentose phosphate pathway	0.825561165843951	-0.191691922856351	30	2	0.00273972602739726	730	7161	230,226	ALDOC,ALDOA
hsa00030	Pentose phosphate pathway	0.825561165843951	-0.191691922856351	30	2	0.00273972602739726	730	7161	230,226	ALDOC,ALDOA
hsa04940	Type I diabetes mellitus	0.828823890962812	-0.187747581923735	43	3	0.00410958904109589	730	7161	5799,3382,1363	PTPRN2,ICA1,CPE
ko04940	Type I diabetes mellitus	0.828823890962812	-0.187747581923735	43	3	0.00410958904109589	730	7161	5799,3382,1363	PTPRN2,ICA1,CPE
hsa04621	NOD-like receptor signaling pathway	0.830903483685037	-0.185241635655366	169	14	0.0191780821917808	730	7161	10910,84674,118429,2633,5580,5603,1147,3709,9474,23236,5602,7099,90550,23710	SUGT1,CARD6,ANTXR2,GBP1,PRKCD,MAPK13,CHUK,ITPR2,ATG5,PLCB1,MAPK10,TLR4,MCU,GABARAPL1
ko04621	NOD-like receptor signaling pathway	0.830903483685037	-0.185241635655366	169	14	0.0191780821917808	730	7161	10910,84674,118429,2633,5580,5603,1147,3709,9474,23236,5602,7099,90550,23710	SUGT1,CARD6,ANTXR2,GBP1,PRKCD,MAPK13,CHUK,ITPR2,ATG5,PLCB1,MAPK10,TLR4,MCU,GABARAPL1
hsa04710	Circadian rhythm	0.839360154434617	-0.175115398312727	31	2	0.00273972602739726	730	7161	5563,8945	PRKAA2,BTRC
ko00052	Galactose metabolism	0.839360154434617	-0.175115398312727	31	2	0.00273972602739726	730	7161	3098,3099	HK1,HK2
ko04710	Circadian rhythm	0.839360154434617	-0.175115398312727	31	2	0.00273972602739726	730	7161	5563,8945	PRKAA2,BTRC
hsa00052	Galactose metabolism	0.839360154434617	-0.175115398312727	31	2	0.00273972602739726	730	7161	3098,3099	HK1,HK2
hsa00360	Phenylalanine metabolism	0.839585200602764	-0.174847317914733	17	1	0.00136986301369863	730	7161	4128	MAOA
ko00360	Phenylalanine metabolism	0.839585200602764	-0.174847317914733	17	1	0.00136986301369863	730	7161	4128	MAOA
ko00071	Fatty acid degradation	0.840477036237438	-0.173785648056454	44	3	0.00410958904109589	730	7161	217,2180,1962	ALDH2,ACSL1,EHHADH
hsa00071	Fatty acid degradation	0.840477036237438	-0.173785648056454	44	3	0.00410958904109589	730	7161	2180,217,1962	ACSL1,ALDH2,EHHADH
ko04658	Th1 and Th2 cell differentiation	0.841578404889779	-0.172476096917045	92	7	0.00958904109589041	730	7161	2625,5588,1147,6777,5603,5602,6775	GATA3,PRKCQ,CHUK,STAT5B,MAPK13,MAPK10,STAT4
hsa04658	Th1 and Th2 cell differentiation	0.841578404889779	-0.172476096917045	92	7	0.00958904109589041	730	7161	2625,5588,1147,6777,5603,5602,6775	GATA3,PRKCQ,CHUK,STAT5B,MAPK13,MAPK10,STAT4
hsa04657	IL-17 signaling pathway	0.849447146125911	-0.163169557432691	93	7	0.00958904109589041	730	7161	1051,53342,1147,5603,3627,5596,5602	CEBPB,IL17D,CHUK,MAPK13,CXCL10,MAPK4,MAPK10
ko04657	IL-17 signaling pathway	0.849447146125911	-0.163169557432691	93	7	0.00958904109589041	730	7161	1051,53342,1147,5603,3627,5596,5602	CEBPB,IL17D,CHUK,MAPK13,CXCL10,MAPK4,MAPK10
hsa03022	Basal transcription factors	0.851438042839894	-0.160828543899113	45	3	0.00410958904109589	730	7161	9569,6875,2963	GTF2IRD1,TAF4B,GTF2F2
ko03022	Basal transcription factors	0.851438042839894	-0.160828543899113	45	3	0.00410958904109589	730	7161	9569,6875,2963	GTF2IRD1,TAF4B,GTF2F2
ko00640	Propanoate metabolism	0.852163216025231	-0.159977202394917	32	2	0.00273972602739726	730	7161	18,1962	ABAT,EHHADH
ko04136	Autophagy - other	0.852163216025231	-0.159977202394917	32	2	0.00273972602739726	730	7161	9474,23710	ATG5,GABARAPL1
hsa04136	Autophagy - other	0.852163216025231	-0.159977202394917	32	2	0.00273972602739726	730	7161	9474,23710	ATG5,GABARAPL1
hsa00640	Propanoate metabolism	0.852163216025231	-0.159977202394917	32	2	0.00273972602739726	730	7161	18,1962	ABAT,EHHADH
hsa00511	Other glycan degradation	0.855976970422985	-0.155511806913772	18	1	0.00136986301369863	730	7161	23324	MAN2B2
ko00511	Other glycan degradation	0.855976970422985	-0.155511806913772	18	1	0.00136986301369863	730	7161	23324	MAN2B2
hsa00531	Glycosaminoglycan degradation	0.870695829664201	-0.138462582794731	19	1	0.00136986301369863	730	7161	10855	HPSE
ko00531	Glycosaminoglycan degradation	0.870695829664201	-0.138462582794731	19	1	0.00136986301369863	730	7161	10855	HPSE
hsa05010	Alzheimer's disease	0.872091384840141	-0.136861061435601	165	13	0.0178082191780822	730	7161	56901,2597,25825,23621,322,2081,7132,4714,2906,3709,23236,4311,6622	NDUFA4L2,GAPDH,BACE2,BACE1,APBB1,ERN1,TNFRSF1A,NDUFB8,GRIN2D,ITPR2,PLCB1,MME,SNCA
ko05010	Alzheimer's disease	0.872091384840141	-0.136861061435601	165	13	0.0178082191780822	730	7161	56901,2597,25825,23621,322,2081,7132,4714,2906,3709,23236,4311,6622	NDUFA4L2,GAPDH,BACE2,BACE1,APBB1,ERN1,TNFRSF1A,NDUFB8,GRIN2D,ITPR2,PLCB1,MME,SNCA
ko05169	Epstein-Barr virus infection	0.874634901177246	-0.133948735497379	199	16	0.0219178082191781	730	7161	1380,1147,7431,958,4734,953,2268,4609,10000,5608,8900,5603,5602,6850,3306,5567	CR2,CHUK,VIM,CD40,NEDD4,ENTPD1,FGR,MYC,AKT3,MAP2K6,CCNA1,MAPK13,MAPK10,SYK,HSPA2,PRKACB
hsa05169	Epstein-Barr virus infection	0.874634901177246	-0.133948735497379	199	16	0.0219178082191781	730	7161	1380,1147,7431,958,4734,953,2268,4609,10000,5608,8900,5603,5602,6850,3306,5567	CR2,CHUK,VIM,CD40,NEDD4,ENTPD1,FGR,MYC,AKT3,MAP2K6,CCNA1,MAPK13,MAPK10,SYK,HSPA2,PRKACB
ko00040	Pentose and glucuronate interconversions	0.875017146981276	-0.133511796266503	34	2	0.00273972602739726	730	7161	7358,51084	UGDH,CRYL1
hsa00040	Pentose and glucuronate interconversions	0.875017146981276	-0.133511796266503	34	2	0.00273972602739726	730	7161	7358,51084	UGDH,CRYL1
ko04130	SNARE interactions in vesicular transport	0.875017146981276	-0.133511796266503	34	2	0.00273972602739726	730	7161	662,8673	BNIP1,VAMP8
hsa04130	SNARE interactions in vesicular transport	0.875017146981276	-0.133511796266503	34	2	0.00273972602739726	730	7161	662,8673	BNIP1,VAMP8
hsa04114	Oocyte meiosis	0.875249104287592	-0.133246742526815	120	9	0.0123287671232877	730	7161	112,6196,3709,3480,9748,5567,8945,64506,107	ADCY6,RPS6KA2,ITPR2,IGF1R,SLK,PRKACB,BTRC,CPEB1,ADCY1
ko04114	Oocyte meiosis	0.875249104287592	-0.133246742526815	120	9	0.0123287671232877	730	7161	112,6196,3709,3480,9748,5567,8945,64506,107	ADCY6,RPS6KA2,ITPR2,IGF1R,SLK,PRKACB,BTRC,CPEB1,ADCY1
ko04630	Jak-STAT signaling pathway	0.883971246062012	-0.123330743952682	156	12	0.0164383561643836	730	7161	53342,3600,5777,10000,6775,4609,2690,6777,3597,3581,3953,3977	IL17D,IL15,PTPN6,AKT3,STAT4,MYC,GHR,STAT5B,IL13RA1,IL9R,LEPR,LIFR
hsa04630	Jak-STAT signaling pathway	0.883971246062012	-0.123330743952682	156	12	0.0164383561643836	730	7161	53342,3600,5777,10000,6775,4609,2690,6777,3597,3581,3953,3977	IL17D,IL15,PTPN6,AKT3,STAT4,MYC,GHR,STAT5B,IL13RA1,IL9R,LEPR,LIFR
hsa00590	Arachidonic acid metabolism	0.88935586260408	-0.117257828172393	62	4	0.00547945205479452	730	7161	5321,113612,9536,1573	PLA2G4A,CYP2U1,PTGES,CYP2J2
ko00590	Arachidonic acid metabolism	0.88935586260408	-0.117257828172393	62	4	0.00547945205479452	730	7161	5321,113612,9536,1573	PLA2G4A,CYP2U1,PTGES,CYP2J2
hsa05340	Primary immunodeficiency	0.894575328860451	-0.111406166208008	36	2	0.00273972602739726	730	7161	5788,958	PTPRC,CD40
ko05340	Primary immunodeficiency	0.894575328860451	-0.111406166208008	36	2	0.00273972602739726	730	7161	5788,958	PTPRC,CD40
hsa05323	Rheumatoid arthritis	0.902570453960773	-0.102508526491544	89	6	0.00821917808219178	730	7161	90423,3600,7099,8792,1435,10673	ATP6V1E2,IL15,TLR4,TNFRSF11A,CSF1,TNFSF13B
ko05323	Rheumatoid arthritis	0.902570453960773	-0.102508526491544	89	6	0.00821917808219178	730	7161	90423,3600,7099,8792,1435,10673	ATP6V1E2,IL15,TLR4,TNFRSF11A,CSF1,TNFSF13B
hsa05164	Influenza A	0.904940498640464	-0.0998860848022663	172	13	0.0178082191780822	730	7161	3627,7098,5579,5608,10000,5611,7132,5603,8794,5578,5602,7099,3306	CXCL10,TLR3,PRKCB,MAP2K6,AKT3,DNAJC3,TNFRSF1A,MAPK13,TNFRSF10C,PRKCA,MAPK10,TLR4,HSPA2
ko05164	Influenza A	0.904940498640464	-0.0998860848022663	172	13	0.0178082191780822	730	7161	3627,7098,5579,5608,10000,5611,7132,5603,8794,5578,5602,7099,3306	CXCL10,TLR3,PRKCB,MAP2K6,AKT3,DNAJC3,TNFRSF1A,MAPK13,TNFRSF10C,PRKCA,MAPK10,TLR4,HSPA2
hsa05012	Parkinson's disease	0.920360509561652	-0.0829898274762447	129	9	0.0123287671232877	730	7161	2861,56901,5071,120892,4714,5413,5567,2770,6622	GPR37,NDUFA4L2,PRKN,LRRK2,NDUFB8,SEPT5,PRKACB,GNAI1,SNCA
hsa_M00160	V-type ATPase, eukaryotes	0.924593009140847	-0.0784016284117692	24	1	0.00136986301369863	730	7161	90423	ATP6V1E2
M00160	V-type ATPase, eukaryotes	0.924593009140847	-0.0784016284117692	24	1	0.00136986301369863	730	7161	90423	ATP6V1E2
ko05160	Hepatitis C	0.928235755306554	-0.0744695317937814	131	9	0.0123287671232877	730	7161	7098,10000,3949,7132,5603,1147,5521,5602,100506658	TLR3,AKT3,LDLR,TNFRSF1A,MAPK13,CHUK,PPP2R2B,MAPK10,OCLN
hsa05160	Hepatitis C	0.928235755306554	-0.0744695317937814	131	9	0.0123287671232877	730	7161	7098,10000,3949,7132,5603,1147,5521,5602,100506658	TLR3,AKT3,LDLR,TNFRSF1A,MAPK13,CHUK,PPP2R2B,MAPK10,OCLN
hsa05134	Legionellosis	0.929461695361593	-0.0731496826089057	55	3	0.00410958904109589	730	7161	664,7099,3306	BNIP3,TLR4,HSPA2
hsa05150	Staphylococcus aureus infection	0.929461695361593	-0.0731496826089057	55	3	0.00410958904109589	730	7161	715,3075,720	C1R,CFH,C4A
ko05150	Staphylococcus aureus infection	0.929461695361593	-0.0731496826089057	55	3	0.00410958904109589	730	7161	715,3075,720	C1R,CFH,C4A
ko05134	Legionellosis	0.929461695361593	-0.0731496826089057	55	3	0.00410958904109589	730	7161	664,7099,3306	BNIP3,TLR4,HSPA2
hsa04975	Fat digestion and absorption	0.931700174782904	-0.0707442169300857	41	2	0.00273972602739726	730	7161	8611,8612	PLPP1,PLPP2
ko05219	Bladder cancer	0.931700174782904	-0.0707442169300857	41	2	0.00273972602739726	730	7161	1890,4609	TYMP,MYC
ko04975	Fat digestion and absorption	0.931700174782904	-0.0707442169300857	41	2	0.00273972602739726	730	7161	8611,8612	PLPP1,PLPP2
hsa05219	Bladder cancer	0.931700174782904	-0.0707442169300857	41	2	0.00273972602739726	730	7161	1890,4609	TYMP,MYC
ko00592	alpha-Linolenic acid metabolism	0.932305928201746	-0.0700942690150049	25	1	0.00136986301369863	730	7161	5321	PLA2G4A
hsa00592	alpha-Linolenic acid metabolism	0.932305928201746	-0.0700942690150049	25	1	0.00136986301369863	730	7161	5321	PLA2G4A
ko05162	Measles	0.935430470698772	-0.0667484591741112	133	9	0.0123287671232877	730	7161	10000,27113,6777,1147,5588,10399,8794,7099,3306	AKT3,BBC3,STAT5B,CHUK,PRKCQ,RACK1,TNFRSF10C,TLR4,HSPA2
hsa05162	Measles	0.935430470698772	-0.0667484591741112	133	9	0.0123287671232877	730	7161	10000,27113,6777,1147,5588,10399,8794,7099,3306	AKT3,BBC3,STAT5B,CHUK,PRKCQ,RACK1,TNFRSF10C,TLR4,HSPA2
ko00860	Porphyrin and chlorophyll metabolism	0.937462742566141	-0.0645782631900588	42	2	0.00273972602739726	730	7161	7390,645	UROS,BLVRB
hsa00860	Porphyrin and chlorophyll metabolism	0.937462742566141	-0.0645782631900588	42	2	0.00273972602739726	730	7161	7390,645	UROS,BLVRB
hsa05416	Viral myocarditis	0.944156290007539	-0.0574635650917568	58	3	0.00410958904109589	730	7161	1604,958,5881	CD55,CD40,RAC3
hsa05140	Leishmaniasis	0.94466955426592	-0.0569200906654926	72	4	0.00547945205479452	730	7161	5603,5579,7099,5777	MAPK13,PRKCB,TLR4,PTPN6
ko05140	Leishmaniasis	0.94466955426592	-0.0569200906654926	72	4	0.00547945205479452	730	7161	5603,5579,7099,5777	MAPK13,PRKCB,TLR4,PTPN6
hsa00270	Cysteine and methionine metabolism	0.947632920766294	-0.0537880660955084	44	2	0.00273972602739726	730	7161	875,1491	CBS,CTH
ko00270	Cysteine and methionine metabolism	0.947632920766294	-0.0537880660955084	44	2	0.00273972602739726	730	7161	875,1491	CBS,CTH
hsa05310	Asthma	0.960541395802419	-0.0402581995216743	30	1	0.00136986301369863	730	7161	958	CD40
ko05310	Asthma	0.960541395802419	-0.0402581995216743	30	1	0.00136986301369863	730	7161	958	CD40
hsa00240	Pyrimidine metabolism	0.961415723842809	-0.0393483685043577	104	6	0.00821917808219178	730	7161	953,5167,1890,129607,4860,114112	ENTPD1,ENPP1,TYMP,CMPK2,PNP,TXNRD3
ko00240	Pyrimidine metabolism	0.961415723842809	-0.0393483685043577	104	6	0.00821917808219178	730	7161	953,5167,1890,129607,4860,114112	ENTPD1,ENPP1,TYMP,CMPK2,PNP,TXNRD3
ko04330	Notch signaling pathway	0.963441413926761	-0.0372435984494477	48	2	0.00273972602739726	730	7161	9253,1488	NUMBL,CTBP2
hsa04330	Notch signaling pathway	0.963441413926761	-0.0372435984494477	48	2	0.00273972602739726	730	7161	9253,1488	NUMBL,CTBP2
ko05206	MicroRNAs in cancer	0.965010687720024	-0.0356161023469443	299	22	0.0301369863013699	730	7161	659,6768,8434,1944,7431,900,23414,5578,54541,6541,8660,5579,4609,3690,4082,4233,7168,4325,10253,85414,5159,1545	BMPR2,ST14,RECK,EFNA3,VIM,CCNG1,ZFPM2,PRKCA,DDIT4,SLC7A1,IRS2,PRKCB,MYC,ITGB3,MARCKS,MET,TPM1,MMP16,SPRY2,SLC45A3,PDGFRB,CYP1B1
hsa05206	MicroRNAs in cancer	0.965010687720024	-0.0356161023469443	299	22	0.0301369863013699	730	7161	659,6768,8434,1944,7431,900,23414,5578,54541,6541,8660,5579,4609,3690,4082,4233,7168,4325,10253,85414,5159,1545	BMPR2,ST14,RECK,EFNA3,VIM,CCNG1,ZFPM2,PRKCA,DDIT4,SLC7A1,IRS2,PRKCB,MYC,ITGB3,MARCKS,MET,TPM1,MMP16,SPRY2,SLC45A3,PDGFRB,CYP1B1
ko05016	Huntington's disease	0.974238539521707	-0.026099098217976	187	12	0.0164383561643836	730	7161	64764,56901,627,1768,4714,27113,3092,9586,10891,6875,23236,1767	CREB3L2,NDUFA4L2,BDNF,DNAH6,NDUFB8,BBC3,HIP1,CREB5,PPARGC1A,TAF4B,PLCB1,DNAH5
hsa05016	Huntington's disease	0.974238539521707	-0.026099098217976	187	12	0.0164383561643836	730	7161	64764,56901,627,1768,4714,27113,3092,9586,10891,6875,23236,1767	CREB3L2,NDUFA4L2,BDNF,DNAH6,NDUFB8,BBC3,HIP1,CREB5,PPARGC1A,TAF4B,PLCB1,DNAH5
hsa05320	Autoimmune thyroid disease	0.974610656138615	-0.0257172147738818	52	2	0.00273972602739726	730	7161	958,7253	CD40,TSHR
ko05320	Autoimmune thyroid disease	0.974610656138615	-0.0257172147738818	52	2	0.00273972602739726	730	7161	958,7253	CD40,TSHR
hsa05203	Viral carcinogenesis	0.976438496041787	-0.0238435147331761	201	13	0.0178082191780822	730	7161	64764,9261,2934,5829,468,5366,5966,8900,6777,9586,6850,5567,85477	CREB3L2,MAPKAPK2,GSN,PXN,ATF4,PMAIP1,REL,CCNA1,STAT5B,CREB5,SYK,PRKACB,SCIN
ko05203	Viral carcinogenesis	0.976438496041787	-0.0238435147331761	201	13	0.0178082191780822	730	7161	64764,9261,2934,5829,468,5366,5966,8900,6777,9586,6850,5567,85477	CREB3L2,MAPKAPK2,GSN,PXN,ATF4,PMAIP1,REL,CCNA1,STAT5B,CREB5,SYK,PRKACB,SCIN
ko00350	Tyrosine metabolism	0.977008929906912	-0.0232594868512253	35	1	0.00136986301369863	730	7161	4128	MAOA
hsa00350	Tyrosine metabolism	0.977008929906912	-0.0232594868512253	35	1	0.00136986301369863	730	7161	4128	MAOA
ko04080	Neuroactive ligand-receptor interaction	0.979340503458822	-0.0208758895080776	276	19	0.026027397260274	730	7161	9170,2898,2561,2894,2566,8973,10203,2570,5028,3953,3363,2900,1138,2690,153,2906,5021,7253,1131	LPAR2,GRIK2,GABRB2,GRID1,GABRG2,CHRNA6,CALCRL,GABRR2,P2RY1,LEPR,HTR7,GRIK4,CHRNA5,GHR,ADRB1,GRIN2D,OXTR,TSHR,CHRM3
hsa04080	Neuroactive ligand-receptor interaction	0.979340503458822	-0.0208758895080776	276	19	0.026027397260274	730	7161	9170,2898,2561,2894,2566,8973,10203,2570,5028,3953,3363,2900,1138,2690,153,2906,5021,7253,1131	LPAR2,GRIK2,GABRB2,GRID1,GABRG2,CHRNA6,CALCRL,GABRR2,P2RY1,LEPR,HTR7,GRIK4,CHRNA5,GHR,ADRB1,GRIN2D,OXTR,TSHR,CHRM3
ko05034	Alcoholism	0.980928419049948	-0.019255789408328	180	11	0.0150684931506849	730	7161	64764,627,55970,468,59345,2775,4128,2906,9586,5569,2770	CREB3L2,BDNF,GNG12,ATF4,GNB4,GNAO1,MAOA,GRIN2D,CREB5,PKIA,GNAI1
hsa05034	Alcoholism	0.980928419049948	-0.019255789408328	180	11	0.0150684931506849	730	7161	64764,627,55970,468,59345,2775,4128,2906,9586,5569,2770	CREB3L2,BDNF,GNG12,ATF4,GNB4,GNAO1,MAOA,GRIN2D,CREB5,PKIA,GNAI1
hsa_M00355	Spliceosome, 35S U5-snRNP	0.981478442569123	-0.0186952292672735	37	1	0.00136986301369863	730	7161	3306	HSPA2
hsa05330	Allograft rejection	0.981478442569123	-0.0186952292672735	37	1	0.00136986301369863	730	7161	958	CD40
M00355	Spliceosome, 35S U5-snRNP	0.981478442569123	-0.0186952292672735	37	1	0.00136986301369863	730	7161	3306	HSPA2
ko05330	Allograft rejection	0.981478442569123	-0.0186952292672735	37	1	0.00136986301369863	730	7161	958	CD40
ko00140	Steroid hormone biosynthesis	0.985429387675103	-0.0146778062247239	58	2	0.00273972602739726	730	7161	79644,1545	SRD5A3,CYP1B1
hsa00140	Steroid hormone biosynthesis	0.985429387675103	-0.0146778062247239	58	2	0.00273972602739726	730	7161	79644,1545	SRD5A3,CYP1B1
hsa04142	Lysosome	0.989425179491847	-0.0106311312584172	123	6	0.00821917808219178	730	7161	55353,10577,1203,1515,9516,27074	LAPTM4B,NPC2,CLN5,CTSV,LITAF,LAMP3
ko04142	Lysosome	0.989425179491847	-0.0106311312584172	123	6	0.00821917808219178	730	7161	55353,10577,1203,1515,9516,27074	LAPTM4B,NPC2,CLN5,CTSV,LITAF,LAMP3
ko04120	Ubiquitin mediated proteolysis	0.989459130201057	-0.0105968182780704	137	7	0.00958904109589041	730	7161	5071,90293,9886,26272,4281,8945,4734	PRKN,KLHL13,RHOBTB1,FBXO4,MID1,BTRC,NEDD4
hsa04120	Ubiquitin mediated proteolysis	0.989459130201057	-0.0105968182780704	137	7	0.00958904109589041	730	7161	5071,90293,9886,26272,4281,8945,4734	PRKN,KLHL13,RHOBTB1,FBXO4,MID1,BTRC,NEDD4
hsa04623	Cytosolic DNA-sensing pathway	0.990888358653477	-0.00915340624194392	63	2	0.00273972602739726	730	7161	3627,1147	CXCL10,CHUK
ko04623	Cytosolic DNA-sensing pathway	0.990888358653477	-0.00915340624194392	63	2	0.00273972602739726	730	7161	3627,1147	CXCL10,CHUK
M00427	Nuclear pore complex	0.992203992552612	-0.00782655518394596	45	1	0.00136986301369863	730	7161	5903	RANBP2
hsa_M00427	Nuclear pore complex	0.992203992552612	-0.00782655518394596	45	1	0.00136986301369863	730	7161	5903	RANBP2
hsa00830	Retinol metabolism	0.992459706316521	-0.00756886541467156	65	2	0.00273972602739726	730	7161	9227,1592	LRAT,CYP26A1
ko00830	Retinol metabolism	0.992459706316521	-0.00756886541467156	65	2	0.00273972602739726	730	7161	9227,1592	LRAT,CYP26A1
hsa00983	Drug metabolism - other enzymes	0.99300375160831	-0.00702083688940795	46	1	0.00136986301369863	730	7161	1890	TYMP
ko00983	Drug metabolism - other enzymes	0.99300375160831	-0.00702083688940795	46	1	0.00136986301369863	730	7161	1890	TYMP
hsa03420	Nucleotide excision repair	0.993721567667077	-0.00629822457552938	47	1	0.00136986301369863	730	7161	2073	ERCC5
ko03420	Nucleotide excision repair	0.993721567667077	-0.00629822457552938	47	1	0.00136986301369863	730	7161	2073	ERCC5
ko05152	Tuberculosis	0.995733025065649	-0.00427610445143212	178	9	0.0123287671232877	730	7161	1051,9902,10000,7132,5603,10333,7099,5602,6850	CEBPB,MRC2,AKT3,TNFRSF1A,MAPK13,TLR6,TLR4,MAPK10,SYK
hsa05152	Tuberculosis	0.995733025065649	-0.00427610445143212	178	9	0.0123287671232877	730	7161	1051,9902,10000,7132,5603,10333,7099,5602,6850	CEBPB,MRC2,AKT3,TNFRSF1A,MAPK13,TLR6,TLR4,MAPK10,SYK
hsa04110	Cell cycle	0.996754060442583	-0.00325121904692025	124	5	0.00684931506849315	730	7161	4088,8555,4609,2810,8900	SMAD3,CDC14B,MYC,SFN,CCNA1
ko04110	Cell cycle	0.996754060442583	-0.00325121904692025	124	5	0.00684931506849315	730	7161	4088,8555,4609,2810,8900	SMAD3,CDC14B,MYC,SFN,CCNA1
hsa03460	Fanconi anemia pathway	0.99705857587736	-0.0029457586123761	54	1	0.00136986301369863	730	7161	79008	SLX1B
ko03460	Fanconi anemia pathway	0.99705857587736	-0.0029457586123761	54	1	0.00136986301369863	730	7161	79008	SLX1B
hsa04612	Antigen processing and presentation	0.997615528615356	-0.00238731876376592	77	2	0.00273972602739726	730	7161	821,3306	CANX,HSPA2
ko03018	RNA degradation	0.997615528615356	-0.00238731876376592	77	2	0.00273972602739726	730	7161	2026,2023	ENO2,ENO1
ko04612	Antigen processing and presentation	0.997615528615356	-0.00238731876376592	77	2	0.00273972602739726	730	7161	821,3306	CANX,HSPA2
hsa03018	RNA degradation	0.997615528615356	-0.00238731876376592	77	2	0.00273972602739726	730	7161	2026,2023	ENO2,ENO1
hsa00190	Oxidative phosphorylation	0.998793892036375	-0.00120683589720459	120	4	0.00547945205479452	730	7161	56901,90423,64077,4714	NDUFA4L2,ATP6V1E2,LHPP,NDUFB8
ko00190	Oxidative phosphorylation	0.998793892036375	-0.00120683589720459	120	4	0.00547945205479452	730	7161	56901,90423,64077,4714	NDUFA4L2,ATP6V1E2,LHPP,NDUFB8
ko05168	Herpes simplex infection	0.999034521632679	-0.000965944741767282	185	8	0.010958904109589	730	7161	7098,3600,29997,7132,9569,1147,6875,5602	TLR3,IL15,NOP53,TNFRSF1A,GTF2IRD1,CHUK,TAF4B,MAPK10
hsa05168	Herpes simplex infection	0.999034521632679	-0.000965944741767282	185	8	0.010958904109589	730	7161	7098,3600,29997,7132,9569,1147,6875,5602	TLR3,IL15,NOP53,TNFRSF1A,GTF2IRD1,CHUK,TAF4B,MAPK10
ko03015	mRNA surveillance pathway	0.999394525020857	-0.000605658353140671	91	2	0.00273972602739726	730	7161	5521,5523	PPP2R2B,PPP2R3A
hsa03015	mRNA surveillance pathway	0.999394525020857	-0.000605658353140671	91	2	0.00273972602739726	730	7161	5521,5523	PPP2R2B,PPP2R3A
hsa03008	Ribosome biogenesis in eukaryotes	0.99980514728788	-0.000194871698376336	79	1	0.00136986301369863	730	7161	55651	NHP2
ko03008	Ribosome biogenesis in eukaryotes	0.99980514728788	-0.000194871698376336	79	1	0.00136986301369863	730	7161	55651	NHP2
ko03013	RNA transport	0.999901160476076	-9.88444088713956e-05	166	5	0.00684931506849315	730	7161	5903,8563,1978,84321,10209	RANBP2,THOC5,EIF4EBP1,THOC3,EIF1
hsa03013	RNA transport	0.999901160476076	-9.88444088713956e-05	166	5	0.00684931506849315	730	7161	5903,8563,1978,84321,10209	RANBP2,THOC5,EIF4EBP1,THOC3,EIF1
hsa05322	Systemic lupus erythematosus	0.999921081316935	-7.89217973080203e-05	132	3	0.00410958904109589	730	7161	715,958,720	C1R,CD40,C4A
ko05322	Systemic lupus erythematosus	0.999921081316935	-7.89217973080203e-05	132	3	0.00410958904109589	730	7161	715,958,720	C1R,CD40,C4A
ko03040	Spliceosome	0.999990272618714	-9.72742859740803e-06	132	2	0.00273972602739726	730	7161	3306,84321	HSPA2,THOC3
hsa03040	Spliceosome	0.999990272618714	-9.72742859740803e-06	132	2	0.00273972602739726	730	7161	3306,84321	HSPA2,THOC3
hsa04740	Olfactory transduction	0.999999999897382	-1.02617800269948e-10	415	10	0.0136986301369863	730	7161	282763,391195,5153,5592,5593,79339,390442,343171,157,5567	OR51B5,OR2T33,PDE1B,PRKG1,PRKG2,OR51B4,OR11H4,OR2W3,GRK3,PRKACB
ko04740	Olfactory transduction	0.999999999897382	-1.02617800269948e-10	415	10	0.0136986301369863	730	7161	282763,391195,5153,5592,5593,79339,390442,343171,157,5567	OR51B5,OR2T33,PDE1B,PRKG1,PRKG2,OR51B4,OR11H4,OR2W3,GRK3,PRKACB
M00037	Melatonin biosynthesis, tryptophan => serotonin => melatonin	0.999999999977046	-2.29543235547719e-11	5	0	0	730	7161
hsa_M00414	Bloom's syndrome complex	0.999999999977046	-2.29543235547719e-11	5	0	0	730	7161
ko00232	Caffeine metabolism	0.999999999977046	-2.29543235547719e-11	5	0	0	730	7161
hsa_M00385	Cul4-DDB1-DDB2 complex	0.999999999977046	-2.29543235547719e-11	5	0	0	730	7161
M00383	ECV complex	0.999999999977046	-2.29543235547719e-11	5	0	0	730	7161
hsa00400	Phenylalanine, tyrosine and tryptophan biosynthesis	0.999999999977046	-2.29543235547719e-11	5	0	0	730	7161
M00079	Keratan sulfate degradation	0.999999999977046	-2.29543235547719e-11	5	0	0	730	7161
hsa_M00042	Catecholamine biosynthesis, tyrosine => dopamine => noradrenaline => adrenaline	0.999999999977046	-2.29543235547719e-11	5	0	0	730	7161
M00289	RF-C complex	0.999999999977046	-2.29543235547719e-11	5	0	0	730	7161
M00071	Glycosphingolipid biosynthesis, neolacto-series, LacCer => nLc4Cer	0.999999999977046	-2.29543235547719e-11	5	0	0	730	7161
hsa_M00386	Cul4-DDB1-CSA complex	0.999999999977046	-2.29543235547719e-11	5	0	0	730	7161
hsa_M00128	Ubiquinone biosynthesis, eukaryotes, 4-hydroxybenzoate => ubiquinone	0.999999999977046	-2.29543235547719e-11	5	0	0	730	7161
hsa_M00079	Keratan sulfate degradation	0.999999999977046	-2.29543235547719e-11	5	0	0	730	7161
M00386	Cul4-DDB1-CSA complex	0.999999999977046	-2.29543235547719e-11	5	0	0	730	7161
hsa_M00382	SCF-FBS complex	0.999999999977046	-2.29543235547719e-11	5	0	0	730	7161
M00042	Catecholamine biosynthesis, tyrosine => dopamine => noradrenaline => adrenaline	0.999999999977046	-2.29543235547719e-11	5	0	0	730	7161
M00307	Pyruvate oxidation, pyruvate => acetyl-CoA	0.999999999977046	-2.29543235547719e-11	5	0	0	730	7161
M00385	Cul4-DDB1-DDB2 complex	0.999999999977046	-2.29543235547719e-11	5	0	0	730	7161
hsa_M00071	Glycosphingolipid biosynthesis, neolacto-series, LacCer => nLc4Cer	0.999999999977046	-2.29543235547719e-11	5	0	0	730	7161
M00414	Bloom's syndrome complex	0.999999999977046	-2.29543235547719e-11	5	0	0	730	7161
hsa_M00289	RF-C complex	0.999999999977046	-2.29543235547719e-11	5	0	0	730	7161
hsa_M00383	ECV complex	0.999999999977046	-2.29543235547719e-11	5	0	0	730	7161
hsa_M00044	Tyrosine degradation, tyrosine => homogentisate	0.999999999977046	-2.29543235547719e-11	5	0	0	730	7161
hsa_M00037	Melatonin biosynthesis, tryptophan => serotonin => melatonin	0.999999999977046	-2.29543235547719e-11	5	0	0	730	7161
M00128	Ubiquinone biosynthesis, eukaryotes, 4-hydroxybenzoate => ubiquinone	0.999999999977046	-2.29543235547719e-11	5	0	0	730	7161
ko00400	Phenylalanine, tyrosine and tryptophan biosynthesis	0.999999999977046	-2.29543235547719e-11	5	0	0	730	7161
M00044	Tyrosine degradation, tyrosine => homogentisate	0.999999999977046	-2.29543235547719e-11	5	0	0	730	7161
hsa00232	Caffeine metabolism	0.999999999977046	-2.29543235547719e-11	5	0	0	730	7161
M00382	SCF-FBS complex	0.999999999977046	-2.29543235547719e-11	5	0	0	730	7161
hsa_M00307	Pyruvate oxidation, pyruvate => acetyl-CoA	0.999999999977046	-2.29543235547719e-11	5	0	0	730	7161
hsa_M00399	Cap binding complex	0.99999999997765	-2.23500662421827e-11	2	0	0	730	7161
M00103	Cholecalciferol biosynthesis	0.99999999997765	-2.23500662421827e-11	2	0	0	730	7161
M00151	Cytochrome bc1 complex respiratory unit	0.99999999997765	-2.23500662421827e-11	2	0	0	730	7161
hsa_M00103	Cholecalciferol biosynthesis	0.99999999997765	-2.23500662421827e-11	2	0	0	730	7161
hsa_M00554	Nucleotide sugar biosynthesis, galactose => UDP-galactose	0.99999999997765	-2.23500662421827e-11	2	0	0	730	7161
M00293	DNA polymerase zeta  complex	0.99999999997765	-2.23500662421827e-11	2	0	0	730	7161
M00106	Conjugated bile acid biosynthesis, cholate => taurocholate/glycocholate	0.99999999997765	-2.23500662421827e-11	2	0	0	730	7161
hsa_M00151	Cytochrome bc1 complex respiratory unit	0.99999999997765	-2.23500662421827e-11	2	0	0	730	7161
M00399	Cap binding complex	0.99999999997765	-2.23500662421827e-11	2	0	0	730	7161
M00068	Glycosphingolipid biosynthesis, globo-series, LacCer => Gb4Cer	0.99999999997765	-2.23500662421827e-11	2	0	0	730	7161
M00554	Nucleotide sugar biosynthesis, galactose => UDP-galactose	0.99999999997765	-2.23500662421827e-11	2	0	0	730	7161
hsa_M00294	DNA polymerase gamma complex	0.99999999997765	-2.23500662421827e-11	2	0	0	730	7161
hsa_M00068	Glycosphingolipid biosynthesis, globo-series, LacCer => Gb4Cer	0.99999999997765	-2.23500662421827e-11	2	0	0	730	7161
hsa_M00293	DNA polymerase zeta  complex	0.99999999997765	-2.23500662421827e-11	2	0	0	730	7161
M00294	DNA polymerase gamma complex	0.99999999997765	-2.23500662421827e-11	2	0	0	730	7161
hsa_M00106	Conjugated bile acid biosynthesis, cholate => taurocholate/glycocholate	0.99999999997765	-2.23500662421827e-11	2	0	0	730	7161
hsa_M00685	Apoptotic machinery	0.999999999977826	-2.21740053618982e-11	4	0	0	730	7161
M00632	Galactose degradation, Leloir pathway, galactose => alpha-D-glucose-1P	0.999999999977826	-2.21740053618982e-11	4	0	0	730	7161
hsa_M00262	DNA polymerase delta complex	0.999999999977826	-2.21740053618982e-11	4	0	0	730	7161
hsa_M00288	RPA complex	0.999999999977826	-2.21740053618982e-11	4	0	0	730	7161
hsa_M00006	Pentose phosphate pathway, oxidative phase, glucose 6P => ribulose 5P	0.999999999977826	-2.21740053618982e-11	4	0	0	730	7161
M00288	RPA complex	0.999999999977826	-2.21740053618982e-11	4	0	0	730	7161
M00402	Translocon-associated protein (TRAP) complex	0.999999999977826	-2.21740053618982e-11	4	0	0	730	7161
M00006	Pentose phosphate pathway, oxidative phase, glucose 6P => ribulose 5P	0.999999999977826	-2.21740053618982e-11	4	0	0	730	7161
M00393	TRAMP complex	0.999999999977826	-2.21740053618982e-11	4	0	0	730	7161
hsa_M00263	DNA polymerase epsilon complex	0.999999999977826	-2.21740053618982e-11	4	0	0	730	7161
M00401	Sec61 complex	0.999999999977826	-2.21740053618982e-11	4	0	0	730	7161
hsa00290	Valine, leucine and isoleucine biosynthesis	0.999999999977826	-2.21740053618982e-11	4	0	0	730	7161
hsa_M00741	Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA	0.999999999977826	-2.21740053618982e-11	4	0	0	730	7161
hsa_M00387	SCF-FBW7 complex	0.999999999977826	-2.21740053618982e-11	4	0	0	730	7161
hsa_M00286	GINS complex	0.999999999977826	-2.21740053618982e-11	4	0	0	730	7161
M00381	SCF-SKP2 complex	0.999999999977826	-2.21740053618982e-11	4	0	0	730	7161
hsa_M00381	SCF-SKP2 complex	0.999999999977826	-2.21740053618982e-11	4	0	0	730	7161
M00261	DNA polymerase alpha / primase complex	0.999999999977826	-2.21740053618982e-11	4	0	0	730	7161
M00110	C19/C18-Steroid hormone biosynthesis, pregnenolone => androstenedione => estrone	0.999999999977826	-2.21740053618982e-11	4	0	0	730	7161
ko00471	D-Glutamine and D-glutamate metabolism	0.999999999977826	-2.21740053618982e-11	4	0	0	730	7161
hsa_M00261	DNA polymerase alpha / primase complex	0.999999999977826	-2.21740053618982e-11	4	0	0	730	7161
hsa_M00133	Polyamine biosynthesis, arginine => agmatine => putrescine => spermidine	0.999999999977826	-2.21740053618982e-11	4	0	0	730	7161
hsa00471	D-Glutamine and D-glutamate metabolism	0.999999999977826	-2.21740053618982e-11	4	0	0	730	7161
M00384	Cul3-SPOP complex	0.999999999977826	-2.21740053618982e-11	4	0	0	730	7161
ko00290	Valine, leucine and isoleucine biosynthesis	0.999999999977826	-2.21740053618982e-11	4	0	0	730	7161
hsa_M00401	Sec61 complex	0.999999999977826	-2.21740053618982e-11	4	0	0	730	7161
hsa_M00632	Galactose degradation, Leloir pathway, galactose => alpha-D-glucose-1P	0.999999999977826	-2.21740053618982e-11	4	0	0	730	7161
M00690	MAPK (ERK5) signaling	0.999999999977826	-2.21740053618982e-11	4	0	0	730	7161
M00263	DNA polymerase epsilon complex	0.999999999977826	-2.21740053618982e-11	4	0	0	730	7161
M00741	Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA	0.999999999977826	-2.21740053618982e-11	4	0	0	730	7161
hsa_M00393	TRAMP complex	0.999999999977826	-2.21740053618982e-11	4	0	0	730	7161
M00387	SCF-FBW7 complex	0.999999999977826	-2.21740053618982e-11	4	0	0	730	7161
hsa_M00148	Succinate dehydrogenase (ubiquinone)	0.999999999977826	-2.21740053618982e-11	4	0	0	730	7161
M00133	Polyamine biosynthesis, arginine => agmatine => putrescine => spermidine	0.999999999977826	-2.21740053618982e-11	4	0	0	730	7161
M00262	DNA polymerase delta complex	0.999999999977826	-2.21740053618982e-11	4	0	0	730	7161
hsa_M00402	Translocon-associated protein (TRAP) complex	0.999999999977826	-2.21740053618982e-11	4	0	0	730	7161
M00148	Succinate dehydrogenase (ubiquinone)	0.999999999977826	-2.21740053618982e-11	4	0	0	730	7161
hsa_M00690	MAPK (ERK5) signaling	0.999999999977826	-2.21740053618982e-11	4	0	0	730	7161
hsa_M00390	Exosome, archaea	0.999999999977826	-2.21740053618982e-11	4	0	0	730	7161
hsa_M00110	C19/C18-Steroid hormone biosynthesis, pregnenolone => androstenedione => estrone	0.999999999977826	-2.21740053618982e-11	4	0	0	730	7161
M00286	GINS complex	0.999999999977826	-2.21740053618982e-11	4	0	0	730	7161
M00685	Apoptotic machinery	0.999999999977826	-2.21740053618982e-11	4	0	0	730	7161
hsa_M00384	Cul3-SPOP complex	0.999999999977826	-2.21740053618982e-11	4	0	0	730	7161
M00390	Exosome, archaea	0.999999999977826	-2.21740053618982e-11	4	0	0	730	7161
M00400	p97-Ufd1-Npl4 complex	0.999999999980103	-1.98967311810377e-11	3	0	0	730	7161
ko00785	Lipoic acid metabolism	0.999999999980103	-1.98967311810377e-11	3	0	0	730	7161
hsa_M00400	p97-Ufd1-Npl4 complex	0.999999999980103	-1.98967311810377e-11	3	0	0	730	7161
hsa_M00392	Ski complex	0.999999999980103	-1.98967311810377e-11	3	0	0	730	7161
M00046	Pyrimidine degradation, uracil => beta-alanine, thymine => 3-aminoisobutanoate	0.999999999980103	-1.98967311810377e-11	3	0	0	730	7161
hsa00780	Biotin metabolism	0.999999999980103	-1.98967311810377e-11	3	0	0	730	7161
hsa_M00108	C21-Steroid hormone biosynthesis, progesterone => corticosterone/aldosterone	0.999999999980103	-1.98967311810377e-11	3	0	0	730	7161
M00392	Ski complex	0.999999999980103	-1.98967311810377e-11	3	0	0	730	7161
M00108	C21-Steroid hormone biosynthesis, progesterone => corticosterone/aldosterone	0.999999999980103	-1.98967311810377e-11	3	0	0	730	7161
hsa_M00410	ESCRT-II complex	0.999999999980103	-1.98967311810377e-11	3	0	0	730	7161
M00297	DNA-PK complex	0.999999999980103	-1.98967311810377e-11	3	0	0	730	7161
hsa_M00132	Inositol phosphate metabolism, Ins(1,3,4)P3 => phytate	0.999999999980103	-1.98967311810377e-11	3	0	0	730	7161
hsa_M00408	ESCRT-0 complex	0.999999999980103	-1.98967311810377e-11	3	0	0	730	7161
hsa_M00134	Polyamine biosynthesis, arginine => ornithine => putrescine	0.999999999980103	-1.98967311810377e-11	3	0	0	730	7161
hsa_M00291	MRN complex	0.999999999980103	-1.98967311810377e-11	3	0	0	730	7161
hsa00785	Lipoic acid metabolism	0.999999999980103	-1.98967311810377e-11	3	0	0	730	7161
hsa_M00046	Pyrimidine degradation, uracil => beta-alanine, thymine => 3-aminoisobutanoate	0.999999999980103	-1.98967311810377e-11	3	0	0	730	7161
M00408	ESCRT-0 complex	0.999999999980103	-1.98967311810377e-11	3	0	0	730	7161
hsa_M00051	Uridine monophosphate biosynthesis, glutamine (+ PRPP) => UMP	0.999999999980103	-1.98967311810377e-11	3	0	0	730	7161
M00291	MRN complex	0.999999999980103	-1.98967311810377e-11	3	0	0	730	7161
M00107	Steroid hormone biosynthesis, cholesterol => prognenolone => progesterone	0.999999999980103	-1.98967311810377e-11	3	0	0	730	7161
M00100	Sphingosine degradation	0.999999999980103	-1.98967311810377e-11	3	0	0	730	7161
M00005	PRPP biosynthesis, ribose 5P => PRPP	0.999999999980103	-1.98967311810377e-11	3	0	0	730	7161
M00410	ESCRT-II complex	0.999999999980103	-1.98967311810377e-11	3	0	0	730	7161
ko00780	Biotin metabolism	0.999999999980103	-1.98967311810377e-11	3	0	0	730	7161
M00051	Uridine monophosphate biosynthesis, glutamine (+ PRPP) => UMP	0.999999999980103	-1.98967311810377e-11	3	0	0	730	7161
M00134	Polyamine biosynthesis, arginine => ornithine => putrescine	0.999999999980103	-1.98967311810377e-11	3	0	0	730	7161
hsa_M00107	Steroid hormone biosynthesis, cholesterol => prognenolone => progesterone	0.999999999980103	-1.98967311810377e-11	3	0	0	730	7161
hsa_M00100	Sphingosine degradation	0.999999999980103	-1.98967311810377e-11	3	0	0	730	7161
M00132	Inositol phosphate metabolism, Ins(1,3,4)P3 => phytate	0.999999999980103	-1.98967311810377e-11	3	0	0	730	7161
hsa_M00118	Glutathione biosynthesis, glutamate => glutathione	0.999999999980103	-1.98967311810377e-11	3	0	0	730	7161
M00118	Glutathione biosynthesis, glutamate => glutathione	0.999999999980103	-1.98967311810377e-11	3	0	0	730	7161
hsa_M00005	PRPP biosynthesis, ribose 5P => PRPP	0.999999999980103	-1.98967311810377e-11	3	0	0	730	7161
hsa_M00297	DNA-PK complex	0.999999999980103	-1.98967311810377e-11	3	0	0	730	7161
M00072	N-glycosylation by oligosaccharyltransferase	0.999999999984294	-1.57059614681111e-11	7	0	0	730	7161
hsa_M00007	Pentose phosphate pathway, non-oxidative phase, fructose 6P => ribose 5P	0.999999999984294	-1.57059614681111e-11	7	0	0	730	7161
M00092	Phosphatidylethanolamine (PE) biosynthesis, ethanolamine => PE	0.999999999984294	-1.57059614681111e-11	7	0	0	730	7161
hsa_M00691	DNA damage-induced cell cycle checkpoints	0.999999999984294	-1.57059614681111e-11	7	0	0	730	7161
M00691	DNA damage-induced cell cycle checkpoints	0.999999999984294	-1.57059614681111e-11	7	0	0	730	7161
hsa_M00396	Lsm 2-8 complex	0.999999999984294	-1.57059614681111e-11	7	0	0	730	7161
M00398	Sm core complex	0.999999999984294	-1.57059614681111e-11	7	0	0	730	7161
hsa_M00072	N-glycosylation by oligosaccharyltransferase	0.999999999984294	-1.57059614681111e-11	7	0	0	730	7161
M00397	Lsm 1-7 complex	0.999999999984294	-1.57059614681111e-11	7	0	0	730	7161
hsa_M00398	Sm core complex	0.999999999984294	-1.57059614681111e-11	7	0	0	730	7161
M00396	Lsm 2-8 complex	0.999999999984294	-1.57059614681111e-11	7	0	0	730	7161
M00007	Pentose phosphate pathway, non-oxidative phase, fructose 6P => ribose 5P	0.999999999984294	-1.57059614681111e-11	7	0	0	730	7161
hsa_M00397	Lsm 1-7 complex	0.999999999984294	-1.57059614681111e-11	7	0	0	730	7161
hsa_M00092	Phosphatidylethanolamine (PE) biosynthesis, ethanolamine => PE	0.999999999984294	-1.57059614681111e-11	7	0	0	730	7161
M00295	BRCA1-associated genome surveillance complex (BASC)	0.999999999986784	-1.32157812586386e-11	16	0	0	730	7161
M00682	Notch signaling	0.999999999986784	-1.32157812586386e-11	16	0	0	730	7161
hsa_M00295	BRCA1-associated genome surveillance complex (BASC)	0.999999999986784	-1.32157812586386e-11	16	0	0	730	7161
hsa_M00682	Notch signaling	0.999999999986784	-1.32157812586386e-11	16	0	0	730	7161
M00073	N-glycan precursor trimming	0.999999999987614	-1.23864737072365e-11	6	0	0	730	7161
M00109	C21-Steroid hormone biosynthesis, progesterone => cortisol/cortisone	0.999999999987614	-1.23864737072365e-11	6	0	0	730	7161
hsa00440	Phosphonate and phosphinate metabolism	0.999999999987614	-1.23864737072365e-11	6	0	0	730	7161
hsa_M00085	Fatty acid biosynthesis, elongation, mitochondria	0.999999999987614	-1.23864737072365e-11	6	0	0	730	7161
hsa_M00090	Phosphatidylcholine (PC) biosynthesis, choline => PC	0.999999999987614	-1.23864737072365e-11	6	0	0	730	7161
hsa_M00285	MCM complex	0.999999999987614	-1.23864737072365e-11	6	0	0	730	7161
hsa_M00424	Shelterin complex	0.999999999987614	-1.23864737072365e-11	6	0	0	730	7161
hsa00750	Vitamin B6 metabolism	0.999999999987614	-1.23864737072365e-11	6	0	0	730	7161
hsa_M00048	Inosine monophosphate biosynthesis, PRPP + glutamine => IMP	0.999999999987614	-1.23864737072365e-11	6	0	0	730	7161
M00395	Decapping complex	0.999999999987614	-1.23864737072365e-11	6	0	0	730	7161
hsa_M00073	N-glycan precursor trimming	0.999999999987614	-1.23864737072365e-11	6	0	0	730	7161
hsa_M00141	C1-unit interconversion, eukaryotes	0.999999999987614	-1.23864737072365e-11	6	0	0	730	7161
M00090	Phosphatidylcholine (PC) biosynthesis, choline => PC	0.999999999987614	-1.23864737072365e-11	6	0	0	730	7161
M00141	C1-unit interconversion, eukaryotes	0.999999999987614	-1.23864737072365e-11	6	0	0	730	7161
hsa_M00109	C21-Steroid hormone biosynthesis, progesterone => cortisol/cortisone	0.999999999987614	-1.23864737072365e-11	6	0	0	730	7161
M00284	Origin recognition complex	0.999999999987614	-1.23864737072365e-11	6	0	0	730	7161
M00048	Inosine monophosphate biosynthesis, PRPP + glutamine => IMP	0.999999999987614	-1.23864737072365e-11	6	0	0	730	7161
ko00440	Phosphonate and phosphinate metabolism	0.999999999987614	-1.23864737072365e-11	6	0	0	730	7161
hsa_M00284	Origin recognition complex	0.999999999987614	-1.23864737072365e-11	6	0	0	730	7161
M00085	Fatty acid biosynthesis, elongation, mitochondria	0.999999999987614	-1.23864737072365e-11	6	0	0	730	7161
M00285	MCM complex	0.999999999987614	-1.23864737072365e-11	6	0	0	730	7161
hsa_M00395	Decapping complex	0.999999999987614	-1.23864737072365e-11	6	0	0	730	7161
ko00750	Vitamin B6 metabolism	0.999999999987614	-1.23864737072365e-11	6	0	0	730	7161
M00424	Shelterin complex	0.999999999987614	-1.23864737072365e-11	6	0	0	730	7161
hsa00472	D-Arginine and D-ornithine metabolism	0.999999999988458	-1.15421561197593e-11	1	0	0	730	7161
ko00472	D-Arginine and D-ornithine metabolism	0.999999999988458	-1.15421561197593e-11	1	0	0	730	7161
hsa_M00043	Thyroid hormone biosynthesis, tyrosine => triiodothyronine/thyroxine	0.999999999988458	-1.15421561197593e-11	1	0	0	730	7161
M00043	Thyroid hormone biosynthesis, tyrosine => triiodothyronine/thyroxine	0.999999999988458	-1.15421561197593e-11	1	0	0	730	7161
M00426	Survival motor neuron (SMN) complex	0.999999999989036	-1.09638125140855e-11	10	0	0	730	7161
M00152	Cytochrome bc1 complex	0.999999999989036	-1.09638125140855e-11	10	0	0	730	7161
hsa_M00351	Spliceosome, U1-snRNP	0.999999999989036	-1.09638125140855e-11	10	0	0	730	7161
M00351	Spliceosome, U1-snRNP	0.999999999989036	-1.09638125140855e-11	10	0	0	730	7161
M00296	BER complex	0.999999999989036	-1.09638125140855e-11	10	0	0	730	7161
ko00920	Sulfur metabolism	0.999999999989036	-1.09638125140855e-11	10	0	0	730	7161
hsa_M00391	Exosome, eukaryotes	0.999999999989036	-1.09638125140855e-11	10	0	0	730	7161
hsa_M00152	Cytochrome bc1 complex	0.999999999989036	-1.09638125140855e-11	10	0	0	730	7161
hsa_M00426	Survival motor neuron (SMN) complex	0.999999999989036	-1.09638125140855e-11	10	0	0	730	7161
M00413	FA core complex	0.999999999989036	-1.09638125140855e-11	10	0	0	730	7161
hsa_M00296	BER complex	0.999999999989036	-1.09638125140855e-11	10	0	0	730	7161
M00391	Exosome, eukaryotes	0.999999999989036	-1.09638125140855e-11	10	0	0	730	7161
hsa00920	Sulfur metabolism	0.999999999989036	-1.09638125140855e-11	10	0	0	730	7161
hsa_M00413	FA core complex	0.999999999989036	-1.09638125140855e-11	10	0	0	730	7161
M00076	Dermatan sulfate degradation	0.999999999989384	-1.06157630812034e-11	9	0	0	730	7161
hsa_M00076	Dermatan sulfate degradation	0.999999999989384	-1.06157630812034e-11	9	0	0	730	7161
hsa_M00687	MAPK (ERK1/2) signaling	0.999999999992328	-7.67232940991093e-12	8	0	0	730	7161
hsa04122	Sulfur relay system	0.999999999992328	-7.67232940991093e-12	8	0	0	730	7161
hsa_M00077	Chondroitin sulfate degradation	0.999999999992328	-7.67232940991093e-12	8	0	0	730	7161
M00077	Chondroitin sulfate degradation	0.999999999992328	-7.67232940991093e-12	8	0	0	730	7161
M00065	GPI-anchor biosynthesis, core oligosaccharide	0.999999999992328	-7.67232940991093e-12	8	0	0	730	7161
M00428	eIF4F complex	0.999999999992328	-7.67232940991093e-12	8	0	0	730	7161
hsa_M00065	GPI-anchor biosynthesis, core oligosaccharide	0.999999999992328	-7.67232940991093e-12	8	0	0	730	7161
hsa_M00428	eIF4F complex	0.999999999992328	-7.67232940991093e-12	8	0	0	730	7161
ko04122	Sulfur relay system	0.999999999992328	-7.67232940991093e-12	8	0	0	730	7161
M00687	MAPK (ERK1/2) signaling	0.999999999992328	-7.67232940991093e-12	8	0	0	730	7161
hsa_M00692	Cell cycle - G1/S transition	0.999999999993684	-6.31641091998983e-12	13	0	0	730	7161
hsa03450	Non-homologous end-joining	0.999999999993684	-6.31641091998983e-12	13	0	0	730	7161
M00036	Leucine degradation, leucine => acetoacetate + acetyl-CoA	0.999999999993684	-6.31641091998983e-12	13	0	0	730	7161
ko03450	Non-homologous end-joining	0.999999999993684	-6.31641091998983e-12	13	0	0	730	7161
hsa_M00036	Leucine degradation, leucine => acetoacetate + acetyl-CoA	0.999999999993684	-6.31641091998983e-12	13	0	0	730	7161
M00692	Cell cycle - G1/S transition	0.999999999993684	-6.31641091998983e-12	13	0	0	730	7161
hsa_M00050	Guanine ribonucleotide biosynthesis IMP => GDP,GTP	0.999999999993684	-6.31641091998983e-12	13	0	0	730	7161
M00050	Guanine ribonucleotide biosynthesis IMP => GDP,GTP	0.999999999993684	-6.31641091998983e-12	13	0	0	730	7161
M00337	Immunoproteasome	0.999999999994241	-5.75919274798978e-12	17	0	0	730	7161
ko00120	Primary bile acid biosynthesis	0.999999999994241	-5.75919274798978e-12	17	0	0	730	7161
hsa_M00337	Immunoproteasome	0.999999999994241	-5.75919274798978e-12	17	0	0	730	7161
M00181	RNA polymerase III, eukaryotes	0.999999999994241	-5.75919274798978e-12	17	0	0	730	7161
hsa_M00181	RNA polymerase III, eukaryotes	0.999999999994241	-5.75919274798978e-12	17	0	0	730	7161
hsa00120	Primary bile acid biosynthesis	0.999999999994241	-5.75919274798978e-12	17	0	0	730	7161
M00389	APC/C complex	0.999999999994735	-5.26491599874474e-12	14	0	0	730	7161
ko00533	Glycosaminoglycan biosynthesis - keratan sulfate	0.999999999994735	-5.26491599874474e-12	14	0	0	730	7161
hsa_M00389	APC/C complex	0.999999999994735	-5.26491599874474e-12	14	0	0	730	7161
M00180	RNA polymerase II, eukaryotes	0.999999999994735	-5.26491599874474e-12	14	0	0	730	7161
hsa_M00180	RNA polymerase II, eukaryotes	0.999999999994735	-5.26491599874474e-12	14	0	0	730	7161
hsa00533	Glycosaminoglycan biosynthesis - keratan sulfate	0.999999999994735	-5.26491599874474e-12	14	0	0	730	7161
M00341	Proteasome, 19S regulatory particle (PA700)	0.999999999995278	-4.72192353446591e-12	19	0	0	730	7161
hsa_M00341	Proteasome, 19S regulatory particle (PA700)	0.999999999995278	-4.72192353446591e-12	19	0	0	730	7161
ko00790	Folate biosynthesis	0.999999999995331	-4.66881234467658e-12	15	0	0	730	7161
hsa00790	Folate biosynthesis	0.999999999995331	-4.66881234467658e-12	15	0	0	730	7161
M00158	F-type ATPase, eukaryotes	0.999999999995331	-4.66881234467658e-12	15	0	0	730	7161
M00340	Proteasome, 20S core particle	0.999999999995331	-4.66881234467658e-12	15	0	0	730	7161
hsa_M00158	F-type ATPase, eukaryotes	0.999999999995331	-4.66881234467658e-12	15	0	0	730	7161
hsa_M00340	Proteasome, 20S core particle	0.999999999995331	-4.66881234467658e-12	15	0	0	730	7161
M00143	NADH dehydrogenase (ubiquinone) Fe-S protein/flavoprotein complex, mitochondria	0.999999999995593	-4.40713255115472e-12	11	0	0	730	7161
ko00130	Ubiquinone and other terpenoid-quinone biosynthesis	0.999999999995593	-4.40713255115472e-12	11	0	0	730	7161
hsa_M00143	NADH dehydrogenase (ubiquinone) Fe-S protein/flavoprotein complex, mitochondria	0.999999999995593	-4.40713255115472e-12	11	0	0	730	7161
hsa00430	Taurine and hypotaurine metabolism	0.999999999995593	-4.40713255115472e-12	11	0	0	730	7161
hsa_M00034	Methionine salvage pathway	0.999999999995593	-4.40713255115472e-12	11	0	0	730	7161
hsa_M00098	Acylglycerol degradation	0.999999999995593	-4.40713255115472e-12	11	0	0	730	7161
M00098	Acylglycerol degradation	0.999999999995593	-4.40713255115472e-12	11	0	0	730	7161
hsa00130	Ubiquinone and other terpenoid-quinone biosynthesis	0.999999999995593	-4.40713255115472e-12	11	0	0	730	7161
M00034	Methionine salvage pathway	0.999999999995593	-4.40713255115472e-12	11	0	0	730	7161
ko00430	Taurine and hypotaurine metabolism	0.999999999995593	-4.40713255115472e-12	11	0	0	730	7161
hsa_M00352	Spliceosome, U2-snRNP	0.999999999997188	-2.81233984124075e-12	20	0	0	730	7161
M00352	Spliceosome, U2-snRNP	0.999999999997188	-2.81233984124075e-12	20	0	0	730	7161
M00430	Exon junction complex (EJC)	1	4.32445744465436e-15	18	0	0	730	7161
hsa_M00430	Exon junction complex (EJC)	1	4.32445744465436e-15	18	0	0	730	7161
hsa03060	Protein export	1.00000000000073	7.28580807081479e-13	23	0	0	730	7161
ko03430	Mismatch repair	1.00000000000073	7.28580807081479e-13	23	0	0	730	7161
ko03060	Protein export	1.00000000000073	7.28580807081479e-13	23	0	0	730	7161
hsa03430	Mismatch repair	1.00000000000073	7.28580807081479e-13	23	0	0	730	7161
M00388	ECS complex	1.00000000000263	2.63210867739505e-12	12	0	0	730	7161
hsa_M00182	RNA polymerase I, eukaryotes	1.00000000000263	2.63210867739505e-12	12	0	0	730	7161
hsa_M00290	Holo-TFIIH complex	1.00000000000263	2.63210867739505e-12	12	0	0	730	7161
M00004	Pentose phosphate pathway (Pentose phosphate cycle)	1.00000000000263	2.63210867739505e-12	12	0	0	730	7161
hsa_M00388	ECS complex	1.00000000000263	2.63210867739505e-12	12	0	0	730	7161
M00104	Bile acid biosynthesis, cholesterol => cholate/chenodeoxycholate	1.00000000000263	2.63210867739505e-12	12	0	0	730	7161
M00290	Holo-TFIIH complex	1.00000000000263	2.63210867739505e-12	12	0	0	730	7161
M00182	RNA polymerase I, eukaryotes	1.00000000000263	2.63210867739505e-12	12	0	0	730	7161
hsa_M00104	Bile acid biosynthesis, cholesterol => cholate/chenodeoxycholate	1.00000000000263	2.63210867739505e-12	12	0	0	730	7161
hsa_M00004	Pentose phosphate pathway (Pentose phosphate cycle)	1.00000000000263	2.63210867739505e-12	12	0	0	730	7161
M00154	Cytochrome c oxidase	1.00000000000566	5.66418991006348e-12	21	0	0	730	7161
hsa_M00154	Cytochrome c oxidase	1.00000000000566	5.66418991006348e-12	21	0	0	730	7161
ko04744	Phototransduction	1.00000000000974	9.73642966586253e-12	28	0	0	730	7161
hsa04744	Phototransduction	1.00000000000974	9.73642966586253e-12	28	0	0	730	7161
ko03020	RNA polymerase	1.00000000001092	1.09193967635277e-11	31	0	0	730	7161
hsa03020	RNA polymerase	1.00000000001092	1.09193967635277e-11	31	0	0	730	7161
hsa03030	DNA replication	1.00000000001143	1.14346473488692e-11	36	0	0	730	7161
ko03030	DNA replication	1.00000000001143	1.14346473488692e-11	36	0	0	730	7161
hsa_M00354	Spliceosome, U4/U6.U5 tri-snRNP	1.00000000001187	1.1875034685697e-11	30	0	0	730	7161
M00354	Spliceosome, U4/U6.U5 tri-snRNP	1.00000000001187	1.1875034685697e-11	30	0	0	730	7161
ko05332	Graft-versus-host disease	1.00000000001384	1.38360836883223e-11	41	0	0	730	7161
hsa05332	Graft-versus-host disease	1.00000000001384	1.38360836883223e-11	41	0	0	730	7161
hsa03440	Homologous recombination	1.00000000001384	1.38360836883223e-11	41	0	0	730	7161
ko03440	Homologous recombination	1.00000000001384	1.38360836883223e-11	41	0	0	730	7161
ko03410	Base excision repair	1.0000000000158	1.57975065596441e-11	33	0	0	730	7161
hsa03410	Base excision repair	1.0000000000158	1.57975065596441e-11	33	0	0	730	7161
hsa03050	Proteasome	1.00000000002392	2.39237167549049e-11	45	0	0	730	7161
ko03050	Proteasome	1.00000000002392	2.39237167549049e-11	45	0	0	730	7161