TermID Term Enrichment logP Genes in Term Target Genes in Term Fraction of Targets in Term Total Target Genes Total Genes Entrez Gene IDs Gene Symbols GO:0008092 cytoskeletal protein binding 3.01892527581694e-08 -17.3157798448368 897 138 0.0821428571428571 1680 17224 116154,57530,2258,3798,50810,55740,5358,3781,79983,9832,29993,83660,11123,25924,4703,1627,400954,341019,26249,10486,287,56062,11034,120892,9638,114327,7145,23406,2009,2934,644150,4133,57821,79884,226,29767,7168,10891,11178,84978,6331,3636,4983,10174,122622,1780,5217,80206,56907,57509,3983,1938,783,6525,22998,114793,4846,57669,56896,11043,60437,4651,54558,9455,29763,3092,84033,5357,10458,56271,130271,79789,1000,57698,270,5071,161436,10580,26052,11013,9050,4430,22837,119,23046,55607,1496,85477,23136,230,65055,140469,22989,4082,5874,282973,3306,2735,54961,2597,51466,91147,79739,6622,23710,28981,2633,4281,23242,10810,4642,10160,2059,3800,79187,26056,4130,283431,128239,4646,2242,9645,171024,5865,5829,51560,55638,9749,23022,6641,4131,54627,257144,6840,9172,55605,23095,7178 PHACTR3,CGN,FGF13,KIF5A,HDGFL3,ENAH,PLS3,KCNN2,POF1B,JAKMIP2,PACSIN1,TLN2,RCAN3,MYRIP,NEB,DBN1,EML6,DCDC1,KLHL3,CAP2,ANK2,KLHL4,DSTN,LRRK2,FEZ1,EFHC1,TNS1,COTL1,EML1,GSN,WIPF3,MAP2,CCDC181,MAP9,ALDOA,TMOD2,TPM1,PPARGC1A,LZTS1,FRMD5,SCN5A,INPPL1,OPHN1,SORBS3,ADSSL1,DYNC1I1,PFN2,FHOD3,SPIRE1,MTUS1,ABLIM1,EEF2,CACNB2,SMTN,LIMCH1,FMNL2,NOS3,EPB41L5,DPYSL5,MID2,CDH26,MYO10,SPATA6,HOMER2,PACSIN3,HIP1,OBSCN,PLS1,BAIAP2,BEX4,PLEKHH2,CLMN,CDH2,SHTN1,AMPD1,PRKN,EML5,SORBS1,DNM3,TMSB15A,PSTPIP2,MYO1B,COBLL1,ADD2,KIF21B,PPP1R9A,CTNNA2,SCIN,EPB41L3,ALDOC,REEP1,MYO3B,MYH15,MARCKS,RAB27B,JAKMIP3,HSPA2,GLI1,SSH3,GAPDH,EVL,TMEM67,TTLL7,SNCA,GABARAPL1,IFT81,GBP1,MID1,COBL,WASF3,MYO1D,FARP1,EPS8,KIF5C,FSD1,RAB11FIP5,MAP1A,GAS2L3,IQGAP3,MYO6,FES,MICAL2,SYNPO2,RAB3B,PXN,RAB6B,SYBU,PHACTR2,PALLD,SNTB1,MAP1B,MAP10,GCSAM,SVIL,MYOM2,KIF21A,KIF1B,TPT1 GO:0030695 GTPase regulator activity 6.40488424407271e-08 -16.5636198815113 316 62 0.0369047619047619 1680 17224 23092,6004,9515,9462,23216,9826,1793,58504,3843,4983,8601,402,29899,10144,6000,23329,1794,26230,9912,84144,55296,1123,113622,57568,26575,1124,57522,57186,153090,23158,54206,9353,10125,11138,10451,54453,10188,116984,83667,54885,9693,120892,55531,55616,26086,57580,22821,116986,7481,9743,23236,125058,55357,5903,57584,577,3071,23677,6001,79822,8829,9882 ARHGAP26,RGS16,STXBP5L,RASAL2,TBC1D1,ARHGEF11,DOCK1,ARHGAP22,IPO5,OPHN1,RGS20,ARL2,GPSM2,FAM13A,RGS7,TBC1D30,DOCK2,TIAM2,ARHGAP44,SYDE2,TBC1D19,CHN1,ADPRHL1,SIPA1L2,RGS17,CHN2,SRGAP1,RALGAPA2,DAB2IP,TBC1D9,ERRFI1,SLIT2,RASGRP1,TBC1D8,VAV3,RIN2,TNK2,ARAP2,SESN2,TBC1D8B,RAPGEF2,LRRK2,ELMOD1,ASAP3,GPSM1,PREX1,RASA3,AGAP2,WNT11,ARHGAP32,PLCB1,TBC1D16,TBC1D2,RANBP2,ARHGAP21,ADGRB3,NCKAP1L,SH3BP4,RGS10,ARHGAP28,NRP1,TBC1D4 GO:0003779 actin binding 1.43015431728576e-07 -15.760313298323 411 74 0.0440476190476191 1680 17224 116154,57530,5071,10580,11013,9050,4430,119,22837,55740,55607,1496,5358,85477,23136,140469,79983,22989,4082,83660,25924,4703,1627,54961,51466,26249,10486,11034,56062,120892,7145,23406,2934,644150,2633,226,29767,7168,23242,10810,4642,3636,2059,4983,122622,5217,56907,80206,3983,4130,1938,783,283431,6525,22998,4646,114793,4846,9645,171024,4651,9455,3092,9749,5357,23022,6641,4131,130271,257144,6840,79789,9172,57698 PHACTR3,CGN,PRKN,SORBS1,TMSB15A,PSTPIP2,MYO1B,ADD2,COBLL1,ENAH,PPP1R9A,CTNNA2,PLS3,SCIN,EPB41L3,MYO3B,POF1B,MYH15,MARCKS,TLN2,MYRIP,NEB,DBN1,SSH3,EVL,KLHL3,CAP2,DSTN,KLHL4,LRRK2,TNS1,COTL1,GSN,WIPF3,GBP1,ALDOA,TMOD2,TPM1,COBL,WASF3,MYO1D,INPPL1,EPS8,OPHN1,ADSSL1,PFN2,SPIRE1,FHOD3,ABLIM1,MAP1A,EEF2,CACNB2,GAS2L3,SMTN,LIMCH1,MYO6,FMNL2,NOS3,MICAL2,SYNPO2,MYO10,HOMER2,HIP1,PHACTR2,PLS1,PALLD,SNTB1,MAP1B,PLEKHH2,GCSAM,SVIL,CLMN,MYOM2,SHTN1 GO:0060589 nucleoside-triphosphatase regulator activity 3.42377253783612e-07 -14.8873526265922 360 66 0.0392857142857143 1680 17224 23092,9462,1793,58504,8601,10144,23329,1794,26230,55296,113622,9531,57568,153090,9353,10125,11138,10188,83667,120892,55531,57580,7481,481,125058,5903,57584,3071,6001,79822,8829,6004,9515,9826,23216,3843,4983,402,29899,6000,134266,9912,84144,1123,26575,1124,57522,57186,54206,23158,93974,54453,10451,116984,54885,9693,26086,55616,22821,116986,9743,23236,55357,577,23677,9882 ARHGAP26,RASAL2,DOCK1,ARHGAP22,RGS20,FAM13A,TBC1D30,DOCK2,TIAM2,TBC1D19,ADPRHL1,BAG3,SIPA1L2,DAB2IP,SLIT2,RASGRP1,TBC1D8,TNK2,SESN2,LRRK2,ELMOD1,PREX1,WNT11,ATP1B1,TBC1D16,RANBP2,ARHGAP21,NCKAP1L,RGS10,ARHGAP28,NRP1,RGS16,STXBP5L,ARHGEF11,TBC1D1,IPO5,OPHN1,ARL2,GPSM2,RGS7,GRPEL2,ARHGAP44,SYDE2,CHN1,RGS17,CHN2,SRGAP1,RALGAPA2,ERRFI1,TBC1D9,ATP5IF1,RIN2,VAV3,ARAP2,TBC1D8B,RAPGEF2,GPSM1,ASAP3,RASA3,AGAP2,ARHGAP32,PLCB1,TBC1D2,ADGRB3,SH3BP4,TBC1D4 GO:0019199 transmembrane receptor protein kinase activity 7.27830218890766e-07 -14.1331980317581 83 24 0.0142857142857143 1680 17224 2042,2264,7301,90,659,51232,130399,1944,4916,4919,93,2047,780,2260,2202,7049,3480,84451,92,2051,657,4233,8829,5159 EPHA3,FGFR4,TYRO3,ACVR1,BMPR2,CRIM1,ACVR1C,EFNA3,NTRK3,ROR1,ACVR2B,EPHB1,DDR1,FGFR1,EFEMP1,TGFBR3,IGF1R,MAP3K21,ACVR2A,EPHB6,BMPR1A,MET,NRP1,PDGFRB GO:0043168 anion binding 7.34045466117419e-07 -14.124694867311 2747 339 0.201785714285714 1680 17224 23092,8448,90,10396,51175,63827,5578,51429,5881,16,8428,5891,7049,57732,1768,5911,25837,2947,29993,5360,2731,130399,8838,120892,5577,1244,93,10082,2770,5167,10769,540,5603,148252,8829,144132,51084,833,55970,26524,241,6334,9748,1718,4983,6507,122622,26038,57143,154661,5592,80216,79958,55137,375449,3156,4860,4651,84725,11069,2194,29763,6262,3092,8476,23236,55760,57494,29941,9508,7060,6713,55353,162394,7222,387751,6296,5321,2042,92170,26052,29984,4430,1147,5596,2870,780,9372,114112,10290,440,8564,84570,153090,5144,379,5874,1767,29887,9846,91807,2617,5163,5208,51700,53354,57580,107,57502,5588,481,23682,57205,2260,260425,6622,953,3627,64208,5579,6999,10400,84451,5066,3248,5033,657,5602,27314,4642,23464,10079,402,3800,875,2621,5028,5585,2047,348751,8435,23263,23678,5593,85007,79659,4646,55964,2242,83666,5210,54795,26873,116984,2946,51560,9693,205,23250,2977,57761,3399,2268,5352,2775,10000,114879,79858,138429,3098,652,79705,129607,493,478,349565,2180,4598,3798,91683,3512,445,3709,18,255928,54830,1687,2152,8153,10382,6196,7881,51166,25890,7220,54805,26577,2051,9353,5159,10125,5567,51062,10188,4139,83667,10257,23670,59338,4919,10110,27244,157,9149,203,8974,2081,5287,221749,123036,58528,5563,84706,7301,55034,860,2335,11149,9886,29091,284716,65997,5217,116835,1938,3480,23461,10846,222537,112,51375,4846,5058,2264,23433,2660,11001,2948,117583,84033,55437,197257,9261,115548,11031,3099,5337,79646,152110,3075,54477,4916,23046,27445,91351,1592,85477,10247,10497,83694,2172,140469,92,22989,4233,134829,3306,1491,2241,7846,4597,2444,79739,64850,7453,27010,5754,2633,3673,5802,5413,22983,10178,23043,8444,659,57144,54622,55784,338323,6402,51655,9912,25851,5580,30845,23551,2963,59,6446,285590,5106,22800,6850,490,5046,9645,5865,389643,9265,55753,81788,10979,4141,116986,9743,79834,9227,23576,390,2200,5608,2329,55605,2669,51776,23095,9536,9619 ARHGAP26,DOC2A,ACVR1,ATP8A1,TUBE1,BCAN,PRKCA,SNX9,RAC3,AARS,STK24,MOK,TGFBR3,ZFYVE28,DNAH6,RAP2A,RAB26,GSTM3,PACSIN1,PLTP,GLDC,ACVR1C,WISP3,LRRK2,PRKAR2B,ABCC2,ACVR2B,GPC6,GNAI1,ENPP1,PLK2,ATP7B,MAPK13,DIRAS1,NRP1,DNHD1,CRYL1,CARS,GNG12,LATS2,ALOX5AP,SCN8A,SLK,DHCR24,OPHN1,SLC1A3,ADSSL1,CHD5,ADCK1,RUNDC3B,PRKG1,ALPK1,DENND1C,FIGN,MAST4,HMGCR,PNP,MYO10,PLEKHA8,RAPGEF4,FASN,PACSIN3,RYR2,HIP1,CDC42BPA,PLCB1,DHX32,RIMKLB,PKN3,ADAMTS3,THBS4,SQLE,LAPTM4B,SLFN5,TRPC3,GVINP1,ACSM3,PLA2G4A,EPHA3,MTG1,DNM3,RHOD,MYO1B,CHUK,MAPK4,GRK6,DDR1,ZFYVE9,TXNRD3,SPEG,ASNS,KMO,COL25A1,DAB2IP,PDE4D,ARL4D,RAB27B,DNAH5,SNX10,GAB2,MYLK3,GARS,PDK1,PFKFB2,CYB5R2,PANK1,PREX1,ADCY1,NLGN4X,PRKCQ,ATP1B1,RAB38,ATP10D,FGFR1,MAGI3,SNCA,ENTPD1,CXCL10,POPDC3,PRKCB,TDO2,PEMT,MAP3K21,PAM,HPGD,P4HA1,BMPR1A,MAPK10,RAB30,MYO1D,GCAT,ATP9A,ARL2,KIF5C,CBS,GAS6,P2RY1,PKN1,EPHB1,FTCDNL1,SOAT2,MCF2L,SGK3,PRKG2,PHYKPL,DYNC2H1,MYO6,SEPT3,FES,PARP9,PFKFB4,TRPM4,OPLAH,ARAP2,GSTM2,RAB6B,RAPGEF2,AK4,ATP11A,GUCY1A2,TRIB3,ID3,FGR,PLOD2,GNAO1,AKT3,OSBPL5,NEK11,PIP5KL1,HK1,BMP4,LRRK1,CMPK2,ATP2B4,ATP1A3,NMNAT3,ACSL1,MVK,KIF5A,SYT12,JCHAIN,ASS1,ITPR2,ABAT,SYT14,NUP62CL,GSDME,F3,RND2,TUBB4A,RPS6KA2,KCNAB1,AADAT,ABI3BP,TRPC1,CNNM2,PCOLCE2,EPHB6,SLIT2,PDGFRB,RASGRP1,PRKACB,ATL1,TNK2,MARK1,SESN2,ABCC4,CEMIP2,PLEKHA1,ROR1,SGK2,SESN1,GRK3,DYRK1B,AK1,P4HA2,ERN1,PIK3C2B,PXDC1,TC2N,RRAGD,PRKAA2,GPT2,TYRO3,MOCOS,RUNX2,FN1,BVES,RHOBTB1,STXBP6,RIMKLA,RASL11B,PFN2,HSPA12B,EEF2,IGF1R,ABCA5,PDE10A,HS3ST5,ADCY6,SNX7,NOS3,PAK1,FGFR4,RHOQ,MSTN,SLC27A2,GSTM4,PARD3B,OBSCN,STRADB,LDHD,MAPKAPK2,FCHO2,RAB31,HK2,PLD1,PANK3,NEK10,CFH,PLEKHA5,NTRK3,KIF21B,PCLO,DDX60L,CYP26A1,SCIN,RIDA,UNC13B,RPS6KL1,FABP6,MYO3B,ACVR2A,MYH15,MET,CLVS2,HSPA2,CTH,FER,TUBA1A,MVD,FRK,TTLL7,ETNPPL,WARS,TPK1,PTK7,GBP1,ITGA2,PTPRS,SEPT5,MAST1,TENM1,TNIK,DYRK3,BMPR2,PAK5,ARL15,MCTP2,NLRP14,SELL,RASD1,ARHGAP44,TECPR1,PRKCD,EHD3,RASD2,GTF2F2,ACTA2,SGK1,SH3PXD2B,PCK2,RRAS2,SYK,ATP2B1,PCSK6,MICAL2,RAB3B,NUGGC,CYTH3,OGDHL,NUAK2,FERMT2,MARS,AGAP2,ARHGAP32,PEAK1,LRAT,DDAH1,RND3,FBN1,MAP2K6,FMO4,KIF21A,GEM,MAP3K20,KIF1B,PTGES,ABCG1 GO:0005096 GTPase activator activity 1.73705552885112e-06 -13.2633191029658 287 54 0.0321428571428571 1680 17224 23092,6004,9515,9462,23216,9826,1793,58504,4983,8601,10144,6000,23329,1794,26230,9912,84144,55296,1123,113622,57568,26575,1124,57522,57186,153090,23158,54206,10125,11138,10451,54453,116984,54885,9693,120892,55531,55616,57580,22821,116986,7481,9743,23236,125058,55357,5903,57584,577,3071,6001,79822,8829,9882 ARHGAP26,RGS16,STXBP5L,RASAL2,TBC1D1,ARHGEF11,DOCK1,ARHGAP22,OPHN1,RGS20,FAM13A,RGS7,TBC1D30,DOCK2,TIAM2,ARHGAP44,SYDE2,TBC1D19,CHN1,ADPRHL1,SIPA1L2,RGS17,CHN2,SRGAP1,RALGAPA2,DAB2IP,TBC1D9,ERRFI1,RASGRP1,TBC1D8,VAV3,RIN2,ARAP2,TBC1D8B,RAPGEF2,LRRK2,ELMOD1,ASAP3,PREX1,RASA3,AGAP2,WNT11,ARHGAP32,PLCB1,TBC1D16,TBC1D2,RANBP2,ARHGAP21,ADGRB3,NCKAP1L,RGS10,ARHGAP28,NRP1,TBC1D4 GO:0042803 protein homodimerization activity 1.50089044031074e-05 -11.106866906115 829 118 0.0702380952380952 1680 17224 4681,3397,90,2898,10859,3512,119,4869,1050,5596,1488,1147,253559,18,51429,54033,22807,869,55607,84679,23475,10247,1890,440,3781,51166,29841,3078,2947,153090,2023,9353,10125,2731,25801,2649,8322,4597,120892,665,1380,57502,25776,467,83700,2260,7453,4088,114088,5167,22806,2995,348093,2633,2081,25937,84451,3248,54937,2073,22876,657,7168,4281,5723,92421,51084,10178,833,23051,2888,9748,26272,4038,875,122622,7164,134266,53342,93986,79187,253461,3157,56952,79955,23767,168620,8614,2690,7020,4040,5593,664,3156,11043,93974,60437,2946,2660,2948,9455,2194,3092,9935,64077,10399,23236,1051,6456,7015,138151,1435,26508,1000,54997,1649,9619,2040 NBL1,ID1,ACVR1,GRIK2,LILRB1,JCHAIN,ADD2,NPM1,CEBPA,MAPK4,CTBP2,CHUK,CADM2,ABAT,SNX9,RBM11,IKZF2,CBLN1,PPP1R9A,SLC9A7,QPRT,RIDA,TYMP,ASNS,KCNN2,AADAT,GRHL1,CFHR1,GSTM3,DAB2IP,ENO1,SLIT2,RASGRP1,GLDC,GCA,NR6A1,FZD4,MVD,LRRK2,BNIP3L,CR2,NLGN4X,CBY1,ATF3,JAM3,FGFR1,WARS,SMAD3,TRIM9,ENPP1,IKZF3,GYPC,RBPMS2,GBP1,ERN1,WWTR1,MAP3K21,HPGD,SOHLH2,ERCC5,INPP5F,BMPR1A,TPM1,MID1,PSPH,CHMP4C,CRYL1,TENM1,CARS,ZHX3,GRB14,SLK,FBXO4,LRP4,CBS,ADSSL1,TPD52L1,GRPEL2,IL17D,FOXP2,FSD1,ZBTB38,HMGCS1,PRTFDC1,PDZD7,FLRT3,BHLHA15,STC2,GHR,TFAP2A,LRP6,PRKG2,BNIP3,HMGCR,MID2,ATP5IF1,CDH26,GSTM2,MSTN,GSTM4,HOMER2,FASN,HIP1,MAFB,LHPP,RACK1,PLCB1,CEBPB,SH3GL2,TERT,NACC2,CSF1,HEYL,CDH2,TESC,DDIT3,ABCG1,STOM GO:0043167 ion binding 1.8855399479686e-05 -10.878711240542 6112 674 0.401190476190476 1680 17224 23092,8448,161823,5153,51175,63827,51429,767,2070,5099,6497,54749,7049,64376,1768,5911,25837,1363,4093,120892,253827,5577,1244,3752,2161,377677,5167,10781,540,26137,2073,148252,144132,4026,51084,833,55970,26524,1573,3655,9748,219749,51440,1123,200558,85416,10960,93664,84171,80216,79958,26002,55137,85460,148979,1131,25946,3156,4860,4651,80258,100289635,2274,2194,6262,3092,5357,715,79740,10150,64506,55760,57494,9508,54814,1015,55353,1000,7222,387751,1466,92170,170685,26052,9658,79695,11226,4430,5596,2870,9378,114112,57484,1138,8564,84570,64219,379,5874,22891,1767,4661,29887,55184,91807,2617,64168,153830,5208,107,23682,444,114991,254042,2260,260425,953,3627,27295,90874,10400,5066,57333,5033,27314,23464,5324,875,2621,5028,9586,5585,2047,51222,85301,23263,4646,23467,678,2242,83666,54795,9260,26873,171425,51560,9693,22821,205,23250,57493,2591,57761,3399,64324,56129,5352,10000,2775,114879,79858,138429,3098,652,129607,493,7178,1911,7093,349565,23321,10626,91683,29995,445,3709,146664,255928,54830,56884,5358,8153,11328,285180,6196,7881,51166,744,2023,346157,3695,30818,4139,10257,475,284161,59338,27244,64943,9149,114088,11278,8974,2081,5287,221749,123036,58528,5563,91694,7301,860,219654,65997,7762,7546,5217,116835,2202,285671,2589,253461,56952,3480,23461,590,126070,2624,80144,10846,222537,112,5058,337876,2264,11043,11001,81790,11282,6920,55437,84033,5151,197257,9261,5337,79845,54997,79646,4311,5071,3075,54947,55769,11237,4916,23046,27445,91351,1592,10247,149076,3422,26468,140469,604,22989,134829,118738,6591,2735,3486,1491,7846,1447,59336,48,54941,8973,2444,64850,4088,5903,154214,2633,5754,3673,5802,5413,55762,23324,10178,54510,8444,54550,659,57144,338323,55784,6402,51655,56978,3046,9912,5523,93986,25851,23551,2963,6446,166336,285590,687,5106,6850,490,5046,92597,9645,389643,1397,9516,81788,10979,144165,9941,4255,27293,1879,23576,79633,91133,2200,2329,7761,133923,388558,56906,9536,23095,781,9310,23077,90,10396,3949,2625,11174,5578,5881,16,8428,23413,7227,5891,57732,2947,11262,29993,5360,2731,8838,2649,130399,114327,93,10082,2770,57630,147372,10769,57089,649,5603,8829,50859,11279,241,9620,23051,6334,1718,4983,6507,122622,26038,79056,2122,3983,26301,57143,6307,5592,154661,119587,375449,9699,220441,84725,54885,8642,11069,7436,29763,7468,8476,23236,148156,4324,747,29941,7060,4147,6713,162394,64754,270,6296,5321,2042,9781,29984,282890,1147,83594,780,9372,4753,152485,10290,440,220929,153090,5144,9846,5163,51700,53354,57580,57502,5588,481,26108,57205,3669,6622,7552,3363,252884,22806,64208,6999,27018,5579,84451,619279,3248,688,657,5602,4306,4281,4642,57088,10079,402,3800,3628,80853,348751,8435,4245,23678,5593,85007,79659,23158,55964,4091,2672,10924,9331,5210,10451,5829,2946,64283,116984,777,2977,148206,7545,643836,2268,7015,7703,283209,79705,11285,478,200035,2180,4598,3798,3512,18,92737,22807,83872,1687,2152,113622,10382,1595,22843,25890,7220,54805,2051,26577,25924,374378,9353,10125,5159,5567,1545,51062,10188,83667,23670,147929,4919,10110,22838,157,2009,203,2934,64919,84706,55034,2335,55893,11149,9871,9886,29091,284716,285440,388403,114805,6319,22856,56122,50862,1938,6940,760,57593,22998,378925,51375,23361,4846,57575,60437,3048,23433,2660,117583,2948,80267,64409,639,64077,26872,144193,5325,115548,2195,11031,3099,51162,152110,57643,1951,54477,80781,79710,255877,144811,821,221833,85477,79149,83852,118987,10497,83694,2172,25925,92,55240,5627,4233,10794,3306,93349,25801,118429,2241,26136,4597,79825,79739,7453,27010,53335,148266,81931,89782,53840,199990,55819,113612,5723,22983,23043,2026,1047,54622,4038,64084,79008,58495,1124,121355,5580,30845,1829,59,10612,115123,22800,8792,55033,9099,5865,10765,3174,2104,3164,9265,55753,55616,5638,4141,116986,9743,23414,79623,79834,9227,473,170691,390,5608,55605,2669,114804,4325,51776,9619 ARHGAP26,DOC2A,ADAL,PDE1B,TUBE1,BCAN,SNX9,CA8,EYA4,PCDH7,SKI,EPDR1,TGFBR3,IKZF5,DNAH6,RAP2A,RAB26,CPE,SMAD9,LRRK2,MSRB3,PRKAR2B,ABCC2,KCND3,F12,CA13,ENPP1,ZNF266,ATP7B,ZBTB20,ERCC5,DIRAS1,DNHD1,LPP,CRYL1,CARS,GNG12,LATS2,CYP2J2,ITGA6,SLK,ZNF25,HPCAL4,CHN1,APLF,ZIC5,LMAN2,CADPS2,LOXL4,ALPK1,DENND1C,MOXD1,FIGN,ZNF518B,GLIS1,CHRM3,ZNF385A,HMGCR,PNP,MYO10,EFHC2,ZNF605,FHL2,FASN,RYR2,HIP1,PLS1,C1R,ZBBX,MBNL2,CPEB1,DHX32,RIMKLB,ADAMTS3,QPCTL,CDH17,LAPTM4B,CDH2,TRPC3,GVINP1,CSRP2,MTG1,NUDT10,DNM3,ZNF516,GALNT12,GALNT6,MYO1B,MAPK4,GRK6,NRXN1,TXNRD3,RNF150,CHRNA5,KMO,COL25A1,PJA1,ARL4D,RAB27B,ZNF365,DNAH5,MYT1,SNX10,DZANK1,MYLK3,GARS,NECAB1,RNF145,PFKFB2,ADCY1,RAB38,ASPH,ZNF618,METAP1D,FGFR1,MAGI3,ENTPD1,CXCL10,PDLIM3,ZNF697,PEMT,PAM,RCN3,P4HA1,RAB30,GCAT,PLAG1,CBS,GAS6,P2RY1,CREB5,PKN1,EPHB1,ZNF219,COL27A1,MCF2L,MYO6,NPTXR,ZFP36L2,FES,PARP9,TRPM4,PDLIM7,OPLAH,CLYBL,RAB6B,RAPGEF2,RASA3,AK4,ATP11A,HEG1,GALNT3,TRIB3,ID3,NSD1,PCDHB7,PLOD2,AKT3,GNAO1,OSBPL5,NEK11,PIP5KL1,HK1,BMP4,CMPK2,ATP2B4,TPT1,PHC1,TLL2,NMNAT3,TRIM2,TRIM16,SYT12,LMCD1,ASS1,ITPR2,MGAT5B,SYT14,NUP62CL,FSTL5,PLS3,RND2,FKBP9,RUFY4,RPS6KA2,KCNAB1,AADAT,MPPED2,ENO1,ZNF391,ITGB7,KCNIP3,MARK1,ABCC4,ATOX1,GDPD1,PLEKHA1,SESN1,NT5DC2,DYRK1B,TRIM9,KLF12,P4HA2,ERN1,PIK3C2B,PXDC1,TC2N,RRAGD,PRKAA2,LONRF1,TYRO3,RUNX2,ZCCHC24,RASL11B,ZNF215,ZIC2,PFN2,HSPA12B,EFEMP1,RNF180,GALNT1,ZBTB38,PRTFDC1,IGF1R,ABCA5,BCHE,ZNF440,GATA2,FRAS1,PDE10A,HS3ST5,ADCY6,PAK1,CHSY3,FGFR4,MID2,SLC27A2,RNF170,MGAT4B,TCEA3,STRADB,OBSCN,PDE8A,LDHD,MAPKAPK2,PLD1,RNF122,TESC,PANK3,MME,PRKN,CFH,LPCAT2,ZNF83,RNF24,NTRK3,KIF21B,PCLO,DDX60L,CYP26A1,RIDA,ZNF362,IDI1,LHX6,MYO3B,BCL6,MYH15,CLVS2,ZNF488,SNAI2,GLI1,IGFBP3,CTH,TUBA1A,CSN2,PRDM13,ACO1,RNF125,CHRNA6,FRK,ETNPPL,SMAD3,RANBP2,RNF217,GBP1,PTK7,ITGA2,PTPRS,SEPT5,ZNF701,MAN2B2,TENM1,PCDH18,DYRK3,NECAB2,BMPR2,PAK5,NLRP14,MCTP2,SELL,RASD1,PRDM8,HBE1,ARHGAP44,PPP2R3A,FOXP2,TECPR1,RASD2,GTF2F2,SGK1,PRICKLE2,SH3PXD2B,KLF9,PCK2,SYK,ATP2B1,PCSK6,MOB1B,MICAL2,NUGGC,CRIP2,LITAF,NUAK2,FERMT2,PRICKLE1,EXOG,MGMT,SMPDL3B,EBF1,DDAH1,FAT4,L3MBTL4,FBN1,FMO4,ZNF214,ZNF474,ZNF808,THAP10,PTGES,KIF1B,CACNA2D1,ZNF235,MYCBP2,ACVR1,ATP8A1,LDLR,GATA3,ADAMTS6,PRKCA,RAC3,AARS,STK24,NCS1,TRPS1,MOK,ZFYVE28,GSTM3,SP140,PACSIN1,PLTP,GLDC,WISP3,NR6A1,ACVR1C,EFHC1,ACVR2B,GPC6,GNAI1,SH3RF1,CCBE1,PLK2,ENTPD7,BMP1,MAPK13,NRP1,SPOCK3,KLF8,ALOX5AP,CELSR1,ZHX3,SCN8A,DHCR24,OPHN1,SLC1A3,ADSSL1,CHD5,PRRG4,MECOM,ABLIM1,GBGT1,ADCK1,MSMO1,PRKG1,RUNDC3B,CPXM2,MAST4,RIMS2,RNF152,PLEKHA8,TBC1D8B,DCHS1,RAPGEF4,VLDLR,PACSIN3,NSD2,CDC42BPA,PLCB1,ZNF558,MMP15,DAGLA,PKN3,THBS4,MATN2,SQLE,SLFN5,SMYD3,AMPD1,ACSM3,PLA2G4A,EPHA3,RNF144A,RHOD,ZNF311,CHUK,NUDT12,DDR1,ZFYVE9,NELL2,ZNF827,SPEG,ASNS,ZNF438,DAB2IP,PDE4D,GAB2,PDK1,CYB5R2,PANK1,PREX1,NLGN4X,PRKCQ,ATP1B1,PYGO1,ATP10D,ISG20,SNCA,ZNF711,HTR7,ZNF396,IKZF3,POPDC3,TDO2,BEX3,PRKCB,MAP3K21,ZNF704,HPGD,KLF5,BMPR1A,MAPK10,NR3C2,MID1,MYO1D,PLSCR4,ATP9A,ARL2,KIF5C,INPP1,KDM7A,FTCDNL1,SOAT2,MGAT1,SGK3,PRKG2,PHYKPL,DYNC2H1,TBC1D9,SEPT3,SMAD6,GFI1,SMPDL3A,B4GALT6,PFKFB4,VAV3,PXN,GSTM2,ARHGEF28,ARAP2,CACNA1E,GUCY1A2,ZNF714,ZIC1,ZFP62,FGR,TERT,PCGF2,PGM2L1,LRRK1,B4GALT7,ATP1A3,NUDT17,ACSL1,MVK,KIF5A,JCHAIN,ABAT,DNER,IKZF2,HMCN1,GSDME,F3,ADPRHL1,TUBB4A,CYP51A1,PPM1E,ABI3BP,TRPC1,CNNM2,EPHB6,PCOLCE2,MYRIP,GALNT18,SLIT2,RASGRP1,PDGFRB,PRKACB,CYP1B1,ATL1,TNK2,SESN2,CEMIP2,ZNF565,ROR1,SGK2,RNF44,GRK3,EML1,AK1,GSN,BCL11B,GPT2,MOCOS,FN1,ZNF395,BVES,SEC24D,RHOBTB1,STXBP6,RIMKLA,CYP4V2,YPEL2,GALNT13,SCD,CHSY1,PCDHB14,RNF141,EEF2,ZNF354A,CA2,EBF4,LIMCH1,RNF148,SNX7,ZNF629,NOS3,PCDH10,CDH26,HBG2,RHOQ,MSTN,PARD3B,GSTM4,EDEM3,GALNT17,PRDM1,LHPP,STEAP1,AMDHD1,PLAGL1,FCHO2,FAT1,RAB31,HK2,EGFL7,NEK10,ZSWIM5,CELSR3,PLEKHA5,COL18A1,MORC4,BCL6B,LACC1,CANX,SP8,SCIN,ZSCAN5A,SETDB2,PDZD8,UNC13B,RPS6KL1,FABP6,ZNF521,ACVR2A,STEAP3,PROS1,MET,ZNF460,HSPA2,SP140L,GCA,ANTXR2,FER,TES,MVD,EFCC1,TTLL7,WARS,TPK1,BCL11A,ZNF569,ZNF93,LMLN,TRIM34,FAAP20,RNF130,CYP2U1,PSPH,MAST1,TNIK,ENO2,CLGN,ARL15,LRP4,CLSTN2,SLX1B,OVOL2,CHN2,GTSF1,PRKCD,EHD3,DSG2,ACTA2,TRIM3,MARCH3,RRAS2,TNFRSF11A,FKBP14,USP2,RAB3B,KDM5B,HNF4G,ESRRG,NR4A1,CYTH3,OGDHL,ASAP3,PRRG1,MARS,AGAP2,ARHGAP32,ZFPM2,GALNT14,PEAK1,LRAT,RERE,ADAMTS17,RND3,MAP2K6,KIF21A,GEM,RNF157,MMP16,MAP3K20,ABCG1 GO:0019904 protein domain specific binding 5.42415929802077e-05 -9.82206254565927 648 94 0.055952380952381 1680 17224 5071,10626,1793,2898,9495,10859,2625,55740,1795,85456,55607,9372,7227,6497,7049,3781,7881,64376,25925,92,8825,153090,5452,9143,5874,3306,5455,8321,10188,51466,468,2597,7846,8322,5777,22941,9829,4779,85012,7431,5577,59338,958,7453,114088,644150,153,4208,4642,55970,6331,3636,57088,860,2335,4291,8325,29899,54602,4734,3761,2624,84632,285590,54206,6812,6850,490,57669,9229,23433,6452,9047,51232,2104,9693,9455,9516,10399,8631,202559,10458,9454,3399,3382,143098,56937,26508,83699,3169,1649,493,100506658,2810 PRKN,TRIM16,DOCK1,GRIK2,AKAP5,LILRB1,GATA3,ENAH,DOCK3,TNKS1BP1,PPP1R9A,ZFYVE9,TRPS1,SKI,TGFBR3,KCNN2,KCNAB1,IKZF5,ZNF521,ACVR2A,LIN7A,DAB2IP,POU2F2,SYNGR3,RAB27B,HSPA2,POU3F3,FZD1,TNK2,EVL,ATF4,GAPDH,TUBA1A,FZD4,PTPN6,SHANK2,DNAJC6,NFE2L1,TCEAL3,VIM,PRKAR2B,PLEKHA1,CD40,WARS,TRIM9,WIPF3,ADRB1,MEF2C,MYO1D,GNG12,SCN5A,INPPL1,PLSCR4,RUNX2,FN1,MLF1,FZD8,GPSM2,NDFIP2,NEDD4,KCNJ4,GATA2,AFAP1L2,SH3PXD2B,ERRFI1,STXBP1,SYK,ATP2B1,EPB41L5,DLGAP1,RHOQ,SH3BP2,SH2D2A,CRIM1,ESRRG,RAPGEF2,HOMER2,LITAF,RACK1,SKAP1,KHDRBS2,BAIAP2,HOMER3,ID3,ICA1,MPP7,PMEPA1,HEYL,SH3BGRL2,FOXA1,DDIT3,ATP2B4,OCLN,SFN GO:0005515 protein binding 7.93034569254561e-05 -9.44222883726661 11470 1188 0.707142857142857 1680 17224 23092,8563,2898,8434,4869,1488,1050,51429,54855,6497,81567,64376,5911,54732,5521,83548,1363,5455,389203,151230,1630,23233,11034,120892,4774,9638,5577,1244,3752,8822,26512,5831,6541,5167,644150,540,79884,56898,153,27113,81617,29767,2073,22876,148252,7168,144132,6331,3655,7082,114781,29899,27241,2290,51440,1123,400961,200558,23767,57522,10960,157638,79958,55137,26002,58494,25946,3786,54558,84159,80258,2274,2194,3092,51390,6616,91947,1203,55812,119391,6158,140606,79789,55353,1000,57698,23348,9522,119,5596,2870,10560,7098,4102,286499,22891,1767,29887,9312,8321,1292,2597,125144,5208,79924,107,7481,1832,444,260425,23710,953,3627,57584,27295,7466,100506013,3912,114336,130940,23621,8325,54845,80381,638,337867,23362,875,2621,2047,51222,84707,3157,2690,678,116931,83666,54795,9260,27077,7424,51560,23250,64324,6136,79858,652,493,1911,116154,2258,10626,57447,3709,146664,5358,8153,221184,285180,6196,51166,3690,744,9832,2023,9771,1627,30818,468,10957,1285,287,475,4779,1380,27244,131544,83985,9149,114088,83439,27345,3638,11278,2081,113146,148523,63973,123036,143384,58528,91694,7301,860,9515,3958,283987,10174,5217,80206,56907,285671,9253,253461,126070,6525,8139,222537,4040,112,9443,9686,56896,153579,1944,26086,9935,55437,84033,221935,202559,10458,257194,55357,5337,10371,56935,3397,1793,4916,23046,22898,85456,55698,55607,57556,10579,604,22989,6591,3486,6207,27152,23507,81550,48,54941,8973,7431,28981,5795,154214,5802,3082,1501,54463,57221,23462,10178,55857,54550,659,57144,56978,51655,7265,93986,2963,8848,7020,6446,9729,6850,490,5046,1843,1112,1397,144165,10979,23022,9454,22943,1879,951,85440,2200,83699,6510,23095,5569,55366,3949,8673,5578,84679,7227,1890,57732,27143,2731,57222,130399,8838,26249,665,114327,2770,57630,649,5603,81848,8829,10501,9902,220108,23216,4291,6480,1718,320,2619,57509,53342,3983,23657,55103,4609,338761,91179,6720,5592,23426,51334,91272,8643,6154,27185,7436,11069,29763,7468,51555,10577,8476,157753,4324,130271,57161,7060,57728,81563,127255,4147,4355,51626,51460,64754,4681,79867,29984,256309,5362,4481,100113407,7373,780,26230,9372,90060,10290,440,11161,230,90525,5144,9846,51700,22941,57580,57502,467,23314,25776,481,26108,474,57205,138162,6622,10207,7552,22806,27018,6999,8900,3248,657,4281,23242,85439,57531,4642,57088,3489,2059,3800,51191,54602,7164,3628,576,54103,222255,11228,219527,151393,79659,23158,54206,4091,30061,10451,6452,5829,64283,2946,5783,56895,6144,7347,3198,7015,84898,4163,6840,79705,1649,23367,81569,11099,25943,2152,113622,4072,22843,7220,2017,25924,3556,5159,10188,83667,8935,23670,10413,23406,2934,51704,10855,10891,7292,9863,84978,5125,9899,55034,9886,11149,26272,29091,56122,100131997,1938,7782,55765,22998,64115,23066,1052,51375,60437,3048,93974,50512,23433,2948,9672,9709,9750,2195,374383,23677,11247,54874,114880,23312,10580,9050,58504,57520,22837,821,10464,85477,963,8555,56605,23254,8496,65055,92,2272,144404,22854,23532,118429,10076,5777,4597,79669,85012,958,148266,55509,55450,4111,3839,1978,348093,6001,142679,22983,2026,23555,9826,152189,6756,10673,79008,10644,150864,654,90550,79187,26056,3761,6324,5580,8614,59,84632,9840,10687,84674,9099,10765,51232,55638,55616,387856,79834,10333,254827,3953,9811,10910,3382,1896,390,1515,55075,3581,256302,4867,9619,8448,5153,134353,5611,253559,6777,79094,55651,1795,767,9722,2070,9531,30850,7049,9858,114907,5366,1768,8499,25837,87769,7253,7080,4212,4093,2706,7039,10486,79971,253827,2161,10781,226,51084,4026,4208,833,26524,55970,9748,150737,134266,10388,51187,662,783,84171,4684,6812,178,114793,2674,1131,29967,6228,3156,627,10117,4651,4259,6775,10203,6604,6262,5357,715,6875,55760,56271,6456,9508,84034,83729,1015,126433,7222,1466,685,170685,26052,9658,11013,348487,720,4430,57596,8601,5318,3597,3937,9378,10584,2838,23136,1138,154043,51339,219790,64219,5874,9143,282973,379,81704,55184,54961,2617,8322,27133,10360,92370,23682,23331,2260,8660,2995,25937,57480,8821,5066,5033,57333,9966,3219,84281,10160,6092,60401,3843,9586,5028,5585,26262,4756,168620,23263,283431,729967,4646,2242,80329,605,167691,9693,23101,83401,64762,10399,6641,57493,5788,57761,3399,2775,10000,7494,3098,57572,8945,3169,7178,23321,91683,50810,445,10859,255928,54830,56884,8320,285966,3781,7881,3257,153562,8825,1310,83660,7099,2115,4703,3695,1604,6520,8612,59338,256536,10538,58473,284618,3626,4133,9895,7132,5287,1746,4300,92421,5563,6004,85450,84959,65997,26040,23209,8809,116835,2202,158405,56952,10505,3480,2624,590,664,25827,2264,5058,11043,11001,81790,9455,221178,79446,8497,5151,374618,197257,9261,91647,1435,26508,54997,2810,4311,10736,5071,60370,3075,9495,23543,55769,11237,27445,869,1496,55296,9715,10247,64429,26468,22859,140469,118738,1491,2735,91147,51466,7846,29997,2257,9446,5919,90737,2444,83700,64850,725,4088,5903,10718,5754,2633,51225,3673,5413,157773,1272,9170,9235,2888,9853,322,6402,2566,3046,9912,5523,25851,4130,23551,10209,285590,5106,2098,92597,9229,9645,5509,81788,9516,56654,54627,65062,79633,91133,1740,5083,6124,56906,9882,57530,23077,90,57718,8712,10396,8495,2625,55740,5881,23413,8428,23201,3078,5002,2947,11262,29993,4105,11123,11138,400954,341019,2649,56062,9829,64798,27351,100271849,7145,192670,93,60485,10082,26084,57491,3071,147372,57821,5924,10769,10512,219699,23111,63920,11178,1948,3636,241,9620,1962,23051,5789,2561,6334,4983,9569,8794,51477,122622,1780,26038,2122,118788,79955,27166,23554,8777,220963,9699,220441,57669,54885,100129654,23127,92104,94015,10567,23236,55286,26355,29941,56937,23096,270,2042,9755,27344,154810,9462,6785,9781,5013,115207,1147,83594,23329,4753,152485,55603,26960,9805,153090,4082,871,5163,79188,84968,5588,125058,131566,5579,41,84451,2887,688,9474,5602,4306,284252,160518,6224,10810,4601,122616,402,6000,81544,4734,84525,80853,26575,23678,57186,5593,85007,9896,8531,55964,2672,10253,10924,171024,116984,123688,4354,55917,2977,8631,1051,2268,9069,7703,7286,9172,2906,11285,100506658,478,196264,23086,4598,3798,79626,3512,18,785,54033,92737,22807,83999,23475,55160,6252,10382,23639,29841,9465,79983,8739,2051,5791,92565,9353,10125,5567,51062,2823,4919,26297,2009,4685,100127983,135112,321,64919,2335,9871,122953,79993,90423,6304,57211,54541,760,6205,57593,118812,4846,2660,9047,117583,23286,1852,639,64077,577,115548,3099,26064,51162,643,161436,1951,3600,54477,79710,144811,1794,92181,79047,83852,10497,25925,9053,55240,4233,80014,5452,10794,3306,57628,25801,90102,2241,26136,55333,80005,79739,339448,7453,9242,199990,54937,84976,3977,5723,23043,1047,5966,4038,79004,6164,1124,30845,1829,9856,10612,128239,22800,8792,54453,5865,4487,2104,3164,9265,55753,4141,9749,116986,9743,900,23414,473,4131,2861,92610,257144,54967,143098,138151,5608,5547,8140,55605,2669,51776,9751,2040 ARHGAP26,THOC5,GRIK2,RECK,NPM1,CTBP2,CEBPA,SNX9,TENT5C,SKI,TXNDC5,IKZF5,RAP2A,TMED9,PPP2R2B,COG3,CPE,POU3F3,SMIM20,KLHL23,DCC,EXOC6B,DSTN,LRRK2,NFIA,FEZ1,PRKAR2B,ABCC2,KCND3,FGF17,INTS6,PYCR1,SLC7A1,ENPP1,WIPF3,ATP7B,MAP9,BDH2,ADRB1,BBC3,CAB39L,TMOD2,ERCC5,INPP5F,DIRAS1,TPM1,DNHD1,SCN5A,ITGA6,TJP1,BTBD9,GPSM2,BBS9,FOXG1,HPCAL4,CHN1,PAIP2B,APLF,FLRT3,SRGAP1,LMAN2,FAM84B,DENND1C,FIGN,MOXD1,JAM2,ZNF385A,KCNQ3,SPATA6,ARID5B,EFHC2,FHL2,FASN,HIP1,AIG1,SNAP25,ARRDC4,CLN5,SPATA7,GSTO2,RPL28,SELENOM,CLMN,LAPTM4B,CDH2,SHTN1,DOCK9,SCAMP1,ADD2,MAPK4,GRK6,SLC19A2,TLR3,MAGEA3,FAM133A,ZNF365,DNAH5,SNX10,KCNB2,FZD1,COL6A2,GAPDH,LRRC75A-AS1,PFKFB2,ADM2,ADCY1,WNT11,DSP,ASPH,MAGI3,GABARAPL1,ENTPD1,CXCL10,ARHGAP21,PDLIM3,WFS1,APELA,LAMB1,CGB2,CCDC148,BACE1,FZD8,ESRP1,CD276,BIK,UBAC2,PSD3,CBS,GAS6,EPHB1,ZNF219,BEX2,HMGCS1,GHR,ZFP36L2,MED12L,PARP9,TRPM4,PDLIM7,B9D1,VEGFC,RAB6B,ATP11A,NSD1,RPL12,NEK11,BMP4,ATP2B4,PHC1,PHACTR3,FGF13,TRIM16,NDRG2,ITPR2,MGAT5B,PLS3,RND2,CPNE2,RUFY4,RPS6KA2,AADAT,ITGB3,MPPED2,JAKMIP2,ENO1,RAPGEF5,DBN1,KCNIP3,ATF4,PNRC1,COL4A3,ANK2,ATOX1,NFE2L1,CR2,SESN1,CRYBG3,SPNS1,DYRK1B,TRIM9,TCF7L1,KCNMB4,INSIG1,KLF12,ERN1,AHNAK2,CIART,NEUROG2,TC2N,CACUL1,RRAGD,LONRF1,TYRO3,RUNX2,STXBP5L,LGALS3,HID1,SORBS3,PFN2,FHOD3,SPIRE1,RNF180,NUMBL,ZBTB38,ZNF440,SMTN,GAN,HS3ST5,LRP6,ADCY6,MED7,VGLL4,DPYSL5,BTNL9,EFNA3,GPSM1,MAFB,STRADB,OBSCN,SDK1,KHDRBS2,BAIAP2,NEGR1,TBC1D2,PLD1,SEMA3A,SMCO4,ID1,DOCK1,NTRK3,KIF21B,DENND3,TNKS1BP1,RADIL,PPP1R9A,SEMA6A,TACC2,BCL6,MYH15,SNAI2,IGFBP3,RPS13,INTU,LRRC8B,TDRD3,ACO1,RNF125,CHRNA6,VIM,IFT81,PTPRJ,RNF217,PTPRS,HGF,CTNND2,RETREG1,ARFGEF3,HEY1,TENM1,KIZ,NECAB2,BMPR2,PAK5,PRDM8,RASD1,TTC1,FOXP2,GTF2F2,TSC22D1,TFAP2A,SGK1,KIAA0408,SYK,ATP2B1,PCSK6,DUSP1,FOXN3,CRIP2,PRICKLE1,FERMT2,PALLD,HOMER3,DKK1,EBF1,CD37,DOCK7,FBN1,SH3BGRL2,SLC1A5,KIF1B,PKIA,LGR4,LDLR,VAMP8,PRKCA,SLC9A7,TRPS1,TYMP,ZFYVE28,PALD1,GLDC,ERGIC1,ACVR1C,WISP3,KLHL3,BNIP3L,EFHC1,GNAI1,SH3RF1,BMP1,MAPK13,SPRY4,NRP1,SEMA6B,MRC2,FAM124A,TBC1D1,MLF1,ST6GAL1,DHCR24,APBA1,GAS1,MTUS1,IL17D,ABLIM1,SLC7A11,RALGPS2,MYC,C1QL4,SCARF2,SREBF1,PRKG1,GRIP1,PRR16,BOD1,PTCH2,RPL26,DISC1,VLDLR,RAPGEF4,PACSIN3,NSD2,PEX5L,NPC2,CDC42BPA,TMEM74,MMP15,PLEKHH2,PELI2,THBS4,WDR19,C1orf21,LRRIQ3,MATN2,MPP2,DYNC2LI1,SFMBT1,SMYD3,NBL1,TCTN2,RHOD,CCDC110,PLXNA2,MSR1,TMEM170B,COL14A1,DDR1,TIAM2,ZFYVE9,CCDC120,SPEG,ASNS,ERG28,ALDOC,SHF,PDE4D,GAB2,CYB5R2,SHANK2,PREX1,NLGN4X,ATF3,SATB2,CBY1,ATP1B1,PYGO1,ATOH1,ATP10D,C9orf116,SNCA,PATJ,ZNF711,IKZF3,BEX3,TDO2,CCNA1,HPGD,BMPR1A,MID1,COBL,STON2,HACE1,MYO1D,PLSCR4,IGFBP6,EPS8,KIF5C,HERC5,NDFIP2,TPD52L1,INPP1,ADGRB2,GSAP,ATXN7L1,RASSF8,LRRC55,RMDN2,DYNC2H1,TBC1D9,ERRFI1,SMAD6,SLC40A1,VAV3,SH3BP2,PXN,ARHGEF28,GSTM2,PTPN13,AGPAT4,RPL21,UCHL3,HOXA1,TERT,PLXDC2,MCC,SVIL,LRRK1,DDIT3,LARP1,ACTL8,PTPN21,C20orf194,F3,ADPRHL1,EPCAM,PPM1E,TRPC1,CTTN,MYRIP,IL1RAP,PDGFRB,TNK2,SESN2,SKAP2,CEMIP2,YAP1,COTL1,GSN,GPRC5B,HPSE,PPARGC1A,TNFSF4,MAGI2,FRMD5,PCSK5,SV2B,MOCOS,RHOBTB1,BVES,FBXO4,STXBP6,PCDHB14,FAM27E3,EEF2,SLC30A4,INAVA,LIMCH1,VSIR,CAND2,CEBPD,SNX7,CDH26,HBG2,ATP5IF1,PODXL2,RHOQ,GSTM4,SDC3,HERPUD1,RIPOR2,FAT1,NCR3LG1,SH3BP4,NXPH4,FNBP1L,OSBPL6,DMXL2,SORBS1,PSTPIP2,ARHGAP22,HECW2,COBLL1,CANX,PIBF1,SCIN,CD53,CDC14B,ERO1B,KAZN,PPFIBP1,REEP1,ACVR2A,FHIT,TMEM120B,NTNG1,PRAME,ANTXR2,PTPRU,PTPN6,MVD,C3orf52,TCEAL3,CD40,ZNF569,BATF3,CAMK2N1,MAGEA12,KPNA3,EIF4EBP1,RBPMS2,RGS10,DUSP19,MAST1,ENO2,TSPAN15,ARHGEF11,CMTM8,SSX1,TNFSF13B,SLX1B,IGF2BP2,FAM117B,BMP6,MCU,FSD1,RAB11FIP5,KCNJ4,SCN1B,PRKCD,STC2,ACTA2,AFAP1L2,TESPA1,PNMA2,CARD6,USP2,KDM5B,CRIM1,SYBU,ASAP3,CCDC184,PEAK1,TLR6,NAALADL2,LEPR,CTIF,SUGT1,ICA1,EDA,RND3,CTSV,UACA,IL9R,NATD1,NPHP1,ABCG1,DOC2A,PDE1B,LSM11,DNAJC3,CADM2,STAT5B,CHAC1,NHP2,DOCK3,CA8,NOS1AP,EYA4,BAG3,CDR2L,TGFBR3,PPP1R26,FBXO32,PMAIP1,DNAH6,PPFIA2,RAB26,GGACT,TSHR,NKX2-1,MEIS2,SMAD9,GJB2,TGFA,CAP2,WLS,MSRB3,F12,ZNF266,ALDOA,CRYL1,LPP,MEF2C,CARS,LATS2,GNG12,SLK,TTC30B,GRPEL2,SYCP2,RSL24D1,BNIP1,CACNB2,LOXL4,NCAM1,STXBP1,AGL,FMNL2,GFRA1,CHRM3,LRP12,RPS23,HMGCR,BDNF,ENAM,MYO10,MGST3,STAT4,CALCRL,SMARCD3,RYR2,PLS1,C1R,TAF4B,DHX32,BEX4,SH3GL2,ADAMTS3,EMILIN2,INHBE,CDH17,FBXO27,TRPC3,CSRP2,BTC,NUDT10,DNM3,ZNF516,TMSB15A,FAM131C,C4A,MYO1B,BEGAIN,RGS20,PKP2,IL13RA1,LCP2,NRXN1,COLEC10,GPR15,EPB41L3,CHRNA5,CNKSR3,DACT1,RTKN2,PJA1,RAB27B,SYNGR3,JAKMIP3,ARL4D,DOCK8,DZANK1,SSH3,GARS,FZD4,KCNH5,NPM3,PXYLP1,RAB38,TTC28,FGFR1,IRS2,GYPC,WWTR1,PLEKHG1,INPP4B,PAM,P4HA1,RCN3,TNFSF15,HOXB9,C2orf88,FARP1,ROBO2,EDA2R,IPO5,CREB5,P2RY1,PKN1,TSPAN17,NEO1,BHLHA15,MCF2L,GAS2L3,MORN2,MYO6,FES,ULBP1,BCL7A,LCA5,RAPGEF2,MCF2L2,ELOVL3,GAREM1,RACK1,SNTB1,HEG1,PTPRC,TRIB3,ID3,GNAO1,AKT3,XBP1,HK1,DOCK6,BTRC,FOXA1,TPT1,TRIM2,SYT12,HDGFL3,ASS1,LILRB1,SYT14,NUP62CL,FSTL5,EOMES,TCAF2,KCNN2,KCNAB1,HPS1,MARVELD2,LIN7A,COL19A1,TLN2,TLR4,ETV1,NEB,ITGB7,CD55,SLC3A2,PLPP2,PLEKHA1,TCERG1L,BATF,PLEKHB1,RUSC1-AS1,INHBC,MAP2,TECPR2,TNFRSF1A,PIK3C2B,DLX2,MLLT3,CHMP4C,PRKAA2,RGS16,ITPRIP,UBASH3B,RASL11B,SETBP1,MLC1,IL18R1,HSPA12B,EFEMP1,KIAA1958,PRTFDC1,SEMA4F,IGF1R,GATA2,BCHE,BNIP3,FBXL2,FGFR4,PAK1,MID2,SLC27A2,RNF170,HOMER2,SPATA13,WDR25,PPFIA4,PDE8A,TEX9,LDHD,MAPKAPK2,ATPAF2,CSF1,HEYL,TESC,SFN,MME,SIX2,PRKN,AVPI1,CFH,AKAP5,RBFOX2,ZNF83,RNF24,PCLO,CBLN1,CTNNA2,TBC1D19,FAM131B,RIDA,ZDHHC6,LHX6,ADGRL1,MYO3B,ZNF488,CTH,GLI1,TMEM67,EVL,TUBA1A,NOP53,FGF12,GSTO1,RARRES2,PAGE5,FRK,JAM3,ETNPPL,C4BPB,SMAD3,RANBP2,NRG3,PTK7,GBP1,ABI3,ITGA2,SEPT5,C8orf48,CNTN1,LPAR2,IL32,GRB14,RUSC2,APBB1,SELL,GABRG2,HBE1,ARHGAP44,PPP2R3A,TECPR1,MAP1A,RASD2,EIF1,SH3PXD2B,PCK2,ESD,MOB1B,DLGAP1,MICAL2,PPP1R3D,NUAK2,LITAF,NPDC1,MAP10,TMEM237,FAT4,L3MBTL4,DLG2,PAX9,RPL4,THAP10,TBC1D4,CGN,MYCBP2,ACVR1,PPP4R4,PAGE1,ATP8A1,PPFIBP2,GATA3,ENAH,RAC3,NCS1,STK24,FAM168A,CFHR1,SLC22A18,GSTM3,SP140,PACSIN1,MAGEA6,RCAN3,TBC1D8,EML6,DCDC1,NR6A1,KLHL4,DNAJC6,DEPTOR,DESI1,MEF2B,TNS1,AGO4,ACVR2B,SAV1,GPC6,ARHGEF26,AHRR,NCKAP1L,CCBE1,CCDC181,RASGRF2,PLK2,SEMA3C,UNC5B,SPART,ZBED8,LZTS1,EFNB2,INPPL1,ALOX5AP,CELSR1,EHHADH,ZHX3,PTPRD,GABRB2,SCN8A,OPHN1,GTF2IRD1,TNFRSF10C,ISYNA1,ADSSL1,DYNC1I1,CHD5,MECOM,PIK3AP1,PDZD7,PRELID1,TSPAN12,MPDZ,SLC16A9,RIMS2,RNF152,EPB41L5,TBC1D8B,TCF24,COLGALT2,TTC30A,TTYH2,RABAC1,PLCB1,C4orf19,FAM162A,PKN3,PMEPA1,IQSEC2,AMPD1,EPHA3,TBKBP1,PCSK1N,AMOTL1,RASAL2,ELOVL4,RNF144A,OTX1,KCTD12,CHUK,NUDT12,TBC1D30,NELL2,ZNF827,TENT5A,NBEA,SCRN1,DAB2IP,MARCKS,SERPINH1,PDK1,TMEM43,PNMA6A,PRKCQ,TBC1D16,DCBLD2,PRKCB,ASIC1,MAP3K21,GRB10,KLF5,ATG5,MAPK10,NR3C2,KCTD1,DENND5B,RPS20,WASF3,MXI1,CLBA1,ARL2,RGS7,GDPD5,NEDD4,HOPX,KDM7A,RGS17,SGK3,RALGAPA2,PRKG2,PHYKPL,FIG4,YBX3,SEPT3,GFI1,SPRY2,SMPDL3A,SYNPO2,ARAP2,HYKK,MPP1,CTTNBP2NL,GUCY1A2,SKAP1,CEBPB,FGR,CLDN12,PCGF2,TUFT1,MYOM2,GRIN2D,B4GALT7,OCLN,ATP1A3,MPZL3,EXPH5,MVK,KIF5A,TNFAIP8L2,JCHAIN,ABAT,CACNB4,RBM11,DNER,IKZF2,KREMEN1,QPRT,ARHGEF10L,RTN1,TUBB4A,LRRC6,GRHL1,AKAP7,POF1B,HRK,EPHB6,PTPRE,FANK1,SLIT2,RASGRP1,PRKACB,ATL1,GPM6A,ROR1,SERGEF,EML1,NCAM2,C8orf88,NCOA7,APBA2,BCL11B,FN1,SEC24D,JDP2,ELOVL7,ATP6V1E2,SATB1,ADGRG6,DDIT4,CA2,RPS11,EBF4,MORN4,NOS3,MSTN,SH2D2A,PARD3B,WWC1,DUSP9,PRDM1,LHPP,ADGRB3,FCHO2,HK2,RAI14,EGFL7,CXCR5,EML5,CELSR3,IL15,PLEKHA5,MORC4,LACC1,DOCK2,UBTD2,KCTD15,SETDB2,UNC13B,ZNF521,MAP7,STEAP3,MET,WWC2,POU2F2,ZNF460,HSPA2,DPP10,GCA,PHLDB2,FER,TES,SYNJ2BP,DOCK5,TTLL7,C1orf174,WARS,MSC,FAAP20,SOHLH2,DISP1,LIFR,PSPH,TNIK,CLGN,REL,LRP4,CUEDC2,RPL34,CHN2,EHD3,DSG2,KIAA0319,TRIM3,IQGAP3,RRAS2,TNFRSF11A,RIN2,RAB3B,MSX1,ESRRG,NR4A1,CYTH3,OGDHL,MARS,PHACTR2,AGAP2,ARHGAP32,CCNG1,ZFPM2,RERE,MAP1B,GPR37,TIFA,GCSAM,CT55,MPP7,NACC2,MAP2K6,PRCP,SLC7A5,KIF21A,GEM,MAP3K20,SNPH,STOM GO:0005057 signal transducer activity, downstream of receptor 8.09755790546643e-05 -9.42136294190233 169 33 0.0196428571428571 1680 17224 2042,7301,23043,90,659,4916,5596,2047,780,55816,26230,8428,3480,23767,92,2051,4233,4091,6850,5159,2264,4093,130399,4919,93,2260,4088,153,84451,5603,657,5602,51776 EPHA3,TYRO3,TNIK,ACVR1,BMPR2,NTRK3,MAPK4,EPHB1,DDR1,DOK5,TIAM2,STK24,IGF1R,FLRT3,ACVR2A,EPHB6,MET,SMAD6,SYK,PDGFRB,FGFR4,SMAD9,ACVR1C,ROR1,ACVR2B,FGFR1,SMAD3,ADRB1,MAP3K21,MAPK13,BMPR1A,MAPK10,MAP3K20 GO:0005261 cation channel activity 0.000140035753879802 -8.8736127831044 318 52 0.030952380952381 1680 17224 27012,55129,6331,57156,10368,2898,6334,55283,3709,2621,3749,785,23413,90550,255231,219527,3761,7881,1138,3781,6324,783,27094,3790,7220,140738,6326,27112,728215,9312,6328,54795,30061,2823,30818,3786,27133,777,56704,8973,22821,6262,3752,2900,60598,27345,3755,41,2906,7222,781,160518 KCNV1,ANO10,SCN5A,TMEM63C,CACNG3,GRIK2,SCN8A,MCOLN3,ITPR2,GAS6,KCNC4,CACNB4,NCS1,MCU,MCOLN2,LRRC55,KCNJ4,KCNAB1,CHRNA5,KCNN2,SCN1B,CACNB2,KCNMB3,KCNS3,TRPC1,TMEM37,SCN2A,FAM155B,FAM155A,KCNB2,SCN3A,TRPM4,SLC40A1,GPM6A,KCNIP3,KCNQ3,KCNH5,CACNA1E,JPH1,CHRNA6,RASA3,RYR2,KCND3,GRIK4,KCNK15,KCNMB4,KCNG1,ASIC1,GRIN2D,TRPC3,CACNA2D1,DENND5B GO:0004674 protein serine/threonine kinase activity 0.000143868019965327 -8.84661420667545 505 75 0.0446428571428571 1680 17224 2042,152110,90,1147,4916,5596,2870,5578,780,8428,5891,10290,7049,6196,83694,140469,92,2051,4233,5159,5567,10188,91807,4139,130399,120892,5588,4919,93,10110,157,2260,9149,5579,10769,2081,84451,5603,657,5602,22983,7301,5563,23043,26524,8444,659,57144,9748,5585,2047,3480,57143,5580,5592,23678,6446,5593,80216,375449,6850,2264,5058,81788,55437,84033,8476,9261,29941,5608,10000,57161,79858,79705,51776 EPHA3,NEK10,ACVR1,CHUK,NTRK3,MAPK4,GRK6,PRKCA,DDR1,STK24,MOK,SPEG,TGFBR3,RPS6KA2,RPS6KL1,MYO3B,ACVR2A,EPHB6,MET,PDGFRB,PRKACB,TNK2,MYLK3,MARK1,ACVR1C,LRRK2,PRKCQ,ROR1,ACVR2B,SGK2,GRK3,FGFR1,DYRK1B,PRKCB,PLK2,ERN1,MAP3K21,MAPK13,BMPR1A,MAPK10,MAST1,TYRO3,PRKAA2,TNIK,LATS2,DYRK3,BMPR2,PAK5,SLK,PKN1,EPHB1,IGF1R,ADCK1,PRKCD,PRKG1,SGK3,SGK1,PRKG2,ALPK1,MAST4,SYK,FGFR4,PAK1,NUAK2,STRADB,OBSCN,CDC42BPA,MAPKAPK2,PKN3,MAP2K6,AKT3,PELI2,NEK11,LRRK1,MAP3K20 GO:0004714 transmembrane receptor protein tyrosine kinase activity 0.000145859798366425 -8.83286468278659 66 17 0.0101190476190476 1680 17224 2042,2264,7301,51232,1944,4916,4919,2047,780,2260,2202,3480,84451,2051,8829,4233,5159 EPHA3,FGFR4,TYRO3,CRIM1,EFNA3,NTRK3,ROR1,EPHB1,DDR1,FGFR1,EFEMP1,IGF1R,MAP3K21,EPHB6,NRP1,MET,PDGFRB GO:0051020 GTPase binding 0.000146244617870105 -8.83022987341765 657 93 0.0553571428571429 1680 17224 23086,23312,685,1793,1795,22898,1794,23329,55607,26230,55160,113622,10497,3257,219790,4233,25924,2023,9771,81704,10125,5159,11138,120892,57580,8822,80005,125058,26297,2260,26084,8660,5903,5924,57480,153,3082,58528,57221,57531,160518,10160,9515,9826,57144,23216,9853,29091,3843,2059,23362,5585,9912,26056,55103,23263,57522,664,128239,23158,79958,8531,4684,114793,2674,9699,220441,2264,5058,54453,10451,64283,116984,54885,9693,23101,9265,11069,55616,221178,84033,116986,51555,55357,85440,29941,23677,2906,23096,54874,9882,57572,23348 EXPH5,DMXL2,BTC,DOCK1,DOCK3,DENND3,DOCK2,TBC1D30,PPP1R9A,TIAM2,ARHGEF10L,ADPRHL1,UNC13B,HPS1,RTKN2,MET,MYRIP,ENO1,RAPGEF5,DOCK8,RASGRP1,PDGFRB,TBC1D8,LRRK2,PREX1,FGF17,DOCK5,TBC1D16,SERGEF,FGFR1,ARHGEF26,IRS2,RANBP2,RASGRF2,PLEKHG1,ADRB1,HGF,RRAGD,ARFGEF3,HACE1,DENND5B,FARP1,STXBP5L,ARHGEF11,PAK5,TBC1D1,RUSC2,STXBP6,IPO5,EPS8,PSD3,PKN1,ARHGAP44,RAB11FIP5,RALGPS2,MCF2L,SRGAP1,BNIP3,IQGAP3,TBC1D9,DENND1C,YBX3,NCAM1,FMNL2,GFRA1,RIMS2,RNF152,FGFR4,PAK1,RIN2,VAV3,ARHGEF28,ARAP2,TBC1D8B,RAPGEF2,MCF2L2,CYTH3,RAPGEF4,ASAP3,SPATA13,OBSCN,AGAP2,PEX5L,TBC1D2,DOCK7,PKN3,SH3BP4,GRIN2D,IQSEC2,FNBP1L,TBC1D4,DOCK6,DOCK9 GO:0017002 activin-activated receptor activity 0.000155749269315596 -8.76726309170036 7 5 0.00297619047619048 1680 17224 92,93,90,659,130399 ACVR2A,ACVR2B,ACVR1,BMPR2,ACVR1C GO:0016247 channel regulator activity 0.000156704378424085 -8.76114946754987 132 27 0.0160714285714286 1680 17224 57628,27012,30818,10368,2258,8673,2257,29763,5318,57463,10399,10110,9378,51440,4734,2822,219527,27345,7881,6324,27094,3790,5592,23678,6446,27075,493 DPP10,KCNV1,KCNIP3,CACNG3,FGF13,VAMP8,FGF12,PACSIN3,PKP2,AMIGO1,RACK1,SGK2,NRXN1,HPCAL4,NEDD4,GPLD1,LRRC55,KCNMB4,KCNAB1,SCN1B,KCNMB3,KCNS3,PRKG1,SGK3,SGK1,TSPAN13,ATP2B4 GO:0005543 phospholipid binding 0.000161140712688165 -8.73323258283634 408 63 0.0375 1680 17224 23092,5321,8448,91683,29091,54477,4430,55784,4983,3512,3709,2621,255928,51429,54830,5217,27445,9372,9912,2152,85477,1687,25851,10497,57732,23263,154661,23678,153090,285590,134829,79958,29993,29887,5360,10125,2242,51375,9846,116984,4139,4651,84725,9693,117583,9265,29763,57580,10979,3092,9743,59338,23236,6622,115548,10400,114879,55353,5287,5337,221749,123036,9619 ARHGAP26,PLA2G4A,DOC2A,SYT12,STXBP6,PLEKHA5,MYO1B,MCTP2,OPHN1,JCHAIN,ITPR2,GAS6,SYT14,SNX9,NUP62CL,PFN2,PCLO,ZFYVE9,ARHGAP44,F3,SCIN,GSDME,TECPR1,UNC13B,ZFYVE28,MCF2L,RUNDC3B,SGK3,DAB2IP,SH3PXD2B,CLVS2,DENND1C,PACSIN1,SNX10,PLTP,RASGRP1,FES,SNX7,GAB2,ARAP2,MARK1,MYO10,PLEKHA8,RAPGEF2,PARD3B,CYTH3,PACSIN3,PREX1,FERMT2,HIP1,ARHGAP32,PLEKHA1,PLCB1,SNCA,FCHO2,PEMT,OSBPL5,LAPTM4B,PIK3C2B,PLD1,PXDC1,TC2N,ABCG1 GO:0008376 acetylgalactosaminyltransferase activity 0.000169340086848032 -8.68360151688839 49 14 0.00833333333333333 1680 17224 337876,2591,26301,2589,8708,11226,79695,8707,114805,64409,22856,283358,374378,79623 CHSY3,GALNT3,GBGT1,GALNT1,B3GALT1,GALNT6,GALNT12,B3GALT2,GALNT13,GALNT17,CHSY1,B4GALNT3,GALNT18,GALNT14 GO:0099106 ion channel regulator activity 0.00023086909995924 -8.37365967490194 94 21 0.0125 1680 17224 57628,27012,30818,8673,29763,57463,10399,10110,9378,51440,4734,219527,27345,7881,6324,27094,5592,23678,3790,6446,27075 DPP10,KCNV1,KCNIP3,VAMP8,PACSIN3,AMIGO1,RACK1,SGK2,NRXN1,HPCAL4,NEDD4,LRRC55,KCNMB4,KCNAB1,SCN1B,KCNMB3,PRKG1,SGK3,KCNS3,SGK1,TSPAN13 GO:0046873 metal ion transmembrane transporter activity 0.000272919009294273 -8.20633547604609 457 68 0.0404761904761905 1680 17224 10368,2898,55283,3709,785,84679,23413,7881,3781,3790,7220,54805,140738,6326,27112,6328,9312,2823,30818,6520,285335,64116,27133,475,56704,81894,3752,481,23516,27345,540,3755,41,150159,160518,27012,6331,6536,6334,6507,9990,2621,3749,90550,255231,3761,219527,7782,6324,783,27094,55117,79815,728215,490,54795,30061,3786,777,22821,6262,2900,60598,2906,7222,781,493,478 CACNG3,GRIK2,MCOLN3,ITPR2,CACNB4,SLC9A7,NCS1,KCNAB1,KCNN2,KCNS3,TRPC1,CNNM2,TMEM37,SCN2A,FAM155B,SCN3A,KCNB2,GPM6A,KCNIP3,SLC3A2,SLC9C1,SLC39A8,KCNH5,ATOX1,JPH1,SLC25A28,KCND3,ATP1B1,SLC39A14,KCNMB4,ATP7B,KCNG1,ASIC1,SLC9B1,DENND5B,KCNV1,SCN5A,SLC6A9,SCN8A,SLC1A3,SLC12A6,GAS6,KCNC4,MCU,MCOLN2,KCNJ4,LRRC55,SLC30A4,SCN1B,CACNB2,KCNMB3,SLC6A15,NIPAL2,FAM155A,ATP2B1,TRPM4,SLC40A1,KCNQ3,CACNA1E,RASA3,RYR2,GRIK4,KCNK15,GRIN2D,TRPC3,CACNA2D1,ATP2B4,ATP1A3 GO:0019899 enzyme binding 0.000278765305365419 -8.18514032955677 2219 263 0.156547619047619 1680 17224 5611,3949,4869,1050,1488,1795,5578,51429,5881,9722,6497,9858,5002,2947,11123,7080,11138,10486,120892,100271849,5577,8822,26084,147372,5924,153,27113,148252,8829,23111,4208,6331,1962,23216,1718,114781,55103,6720,57522,79958,4684,6812,114793,2674,9699,220441,91272,54885,11069,6262,51555,10577,23236,56271,29941,55353,23096,1000,64754,23348,2042,685,26052,29984,9781,5318,119,5596,780,23329,26230,51339,4102,26960,153090,219790,4082,5144,282973,29887,81704,9846,8322,5208,57580,481,1832,23331,125058,2260,23710,8660,5579,7466,57480,84451,4281,57531,160518,57088,10160,8325,23621,2059,3843,875,23362,2621,5585,2047,26262,4734,23263,2690,23158,8531,54206,4091,10253,83666,10451,64283,2946,116984,23101,9693,10399,55917,8631,5788,1051,57761,2268,9172,2906,57572,493,116154,23086,10859,18,2152,8153,113622,55160,3257,9465,3690,9832,2051,2023,25924,9771,3556,5159,5567,10125,10188,468,287,4919,23406,256536,26297,51704,2081,10891,9863,143384,84978,58528,91694,7301,2335,9515,9886,29091,285671,3480,1938,590,112,664,25827,2264,5058,93974,23433,11001,2948,221178,23286,84033,5151,639,55357,9261,23677,54874,2810,23312,5071,9495,1793,4916,22898,85456,1794,55607,10497,2272,80014,4233,3306,2241,5777,54941,958,80005,7453,55450,4088,5903,5795,10718,154214,2633,142679,3082,57221,55857,23555,57144,2888,9826,9853,4038,6402,9912,26056,8614,5580,23551,59,128239,6850,92597,5509,54453,9099,9265,55616,116986,2861,85440,138151,257144,390,5608,1740,9882,5569,2040 DNAJC3,LDLR,NPM1,CEBPA,CTBP2,DOCK3,PRKCA,SNX9,RAC3,NOS1AP,SKI,PPP1R26,SLC22A18,GSTM3,RCAN3,NKX2-1,TBC1D8,CAP2,LRRK2,MEF2B,PRKAR2B,FGF17,ARHGEF26,CCBE1,RASGRF2,ADRB1,BBC3,DIRAS1,NRP1,SPART,MEF2C,SCN5A,EHHADH,TBC1D1,DHCR24,BTBD9,RALGPS2,SREBF1,SRGAP1,DENND1C,NCAM1,STXBP1,FMNL2,GFRA1,RIMS2,RNF152,BOD1,TBC1D8B,RAPGEF4,RYR2,PEX5L,NPC2,PLCB1,BEX4,PKN3,LAPTM4B,IQSEC2,CDH2,SMYD3,DOCK9,EPHA3,BTC,DNM3,RHOD,RNF144A,PKP2,ADD2,MAPK4,DDR1,TBC1D30,TIAM2,DACT1,MAGEA3,NBEA,DAB2IP,RTKN2,MARCKS,PDE4D,JAKMIP3,SNX10,DOCK8,GAB2,FZD4,PFKFB2,PREX1,ATP1B1,DSP,TTC28,TBC1D16,FGFR1,GABARAPL1,IRS2,PRKCB,WFS1,PLEKHG1,MAP3K21,MID1,HACE1,DENND5B,PLSCR4,FARP1,FZD8,BACE1,EPS8,IPO5,CBS,PSD3,GAS6,PKN1,EPHB1,TSPAN17,NEDD4,MCF2L,GHR,TBC1D9,YBX3,ERRFI1,SMAD6,SPRY2,PARP9,VAV3,ARHGEF28,GSTM2,ARAP2,MCF2L2,RAPGEF2,RACK1,CTTNBP2NL,SKAP1,PTPRC,CEBPB,TRIB3,FGR,MYOM2,GRIN2D,DOCK6,ATP2B4,PHACTR3,EXPH5,LILRB1,ABAT,F3,RND2,ADPRHL1,ARHGEF10L,HPS1,AKAP7,ITGB3,JAKMIP2,EPHB6,ENO1,MYRIP,RAPGEF5,IL1RAP,PDGFRB,PRKACB,RASGRP1,TNK2,ATF4,ANK2,ROR1,COTL1,TCERG1L,SERGEF,GPRC5B,ERN1,PPARGC1A,MAGI2,CACUL1,FRMD5,RRAGD,LONRF1,TYRO3,FN1,STXBP5L,RHOBTB1,STXBP6,RNF180,IGF1R,EEF2,BCHE,ADCY6,BNIP3,FBXL2,FGFR4,PAK1,ATP5IF1,RHOQ,SLC27A2,GSTM4,SPATA13,WWC1,OBSCN,PDE8A,PRDM1,TBC1D2,MAPKAPK2,SH3BP4,FNBP1L,SFN,DMXL2,PRKN,AKAP5,DOCK1,NTRK3,DENND3,TNKS1BP1,DOCK2,PPP1R9A,UNC13B,FHIT,WWC2,MET,HSPA2,FER,PTPN6,RNF125,CD40,DOCK5,WARS,CAMK2N1,SMAD3,RANBP2,PTPRJ,NRG3,RNF217,GBP1,DUSP19,HGF,ARFGEF3,KIZ,TSPAN15,PAK5,GRB14,ARHGEF11,RUSC2,LRP4,SELL,ARHGAP44,RAB11FIP5,STC2,PRKCD,RASD2,ACTA2,IQGAP3,SYK,MOB1B,PPP1R3D,RIN2,USP2,CYTH3,ASAP3,AGAP2,GPR37,DOCK7,NACC2,GCSAM,RND3,MAP2K6,DLG2,TBC1D4,PKIA,STOM GO:0004672 protein kinase activity 0.000280148630691943 -8.1801902717324 652 91 0.0541666666666667 1680 17224 2042,685,152110,90,1147,4916,5596,6777,2870,5578,780,8428,5891,10290,6196,7049,83694,140469,92,2051,4233,5159,5567,2241,10188,91807,4139,5163,130399,27133,120892,5588,4919,93,8822,10110,2444,157,2260,9149,5579,10769,5754,2081,84451,5603,3082,657,8829,5602,22983,7301,5563,23043,26524,8444,659,57144,9748,5585,2047,2202,3480,57143,5580,23678,5592,5593,6446,80216,375449,6850,2242,2264,5058,51232,1944,81788,55437,84033,8476,79834,9261,2268,29941,5608,10000,57161,79858,79705,51776 EPHA3,BTC,NEK10,ACVR1,CHUK,NTRK3,MAPK4,STAT5B,GRK6,PRKCA,DDR1,STK24,MOK,SPEG,RPS6KA2,TGFBR3,RPS6KL1,MYO3B,ACVR2A,EPHB6,MET,PDGFRB,PRKACB,FER,TNK2,MYLK3,MARK1,PDK1,ACVR1C,KCNH5,LRRK2,PRKCQ,ROR1,ACVR2B,FGF17,SGK2,FRK,GRK3,FGFR1,DYRK1B,PRKCB,PLK2,PTK7,ERN1,MAP3K21,MAPK13,HGF,BMPR1A,NRP1,MAPK10,MAST1,TYRO3,PRKAA2,TNIK,LATS2,DYRK3,BMPR2,PAK5,SLK,PKN1,EPHB1,EFEMP1,IGF1R,ADCK1,PRKCD,SGK3,PRKG1,PRKG2,SGK1,ALPK1,MAST4,SYK,FES,FGFR4,PAK1,CRIM1,EFNA3,NUAK2,STRADB,OBSCN,CDC42BPA,PEAK1,MAPKAPK2,FGR,PKN3,MAP2K6,AKT3,PELI2,NEK11,LRRK1,MAP3K20 GO:0004702 signal transducer, downstream of receptor, with serine/threonine kinase activity 0.000299125067917132 -8.11464878468309 123 25 0.0148809523809524 1680 17224 2042,2264,7301,23043,90,659,130399,5596,4916,4919,93,2047,780,8428,2260,3480,84451,92,5603,2051,657,4233,5602,51776,5159 EPHA3,FGFR4,TYRO3,TNIK,ACVR1,BMPR2,ACVR1C,MAPK4,NTRK3,ROR1,ACVR2B,EPHB1,DDR1,STK24,FGFR1,IGF1R,MAP3K21,ACVR2A,MAPK13,EPHB6,BMPR1A,MET,MAPK10,MAP3K20,PDGFRB GO:0098772 molecular function regulator 0.000300738292351547 -8.10927013204161 1837 222 0.132142857142857 1680 17224 23092,116154,10368,57718,2258,8434,5611,8673,50810,4869,1795,10144,6497,55160,113622,9531,57568,1890,9858,7881,3257,3790,5521,26577,11123,9771,9353,10125,5159,11138,10188,30818,83667,1285,8838,7039,120892,55531,5577,8822,10110,26297,26084,3626,27345,51704,3071,5924,153,649,79822,10512,5274,8829,7292,50859,27012,6004,241,2335,9515,3958,23216,4983,29899,11005,51440,134266,2202,53342,1123,55103,10129,10505,23767,57522,5592,4040,4684,79958,2674,91272,2264,627,93974,2660,54885,11069,26086,221178,29763,84033,23236,55357,4324,577,7060,1435,23677,83729,23096,10371,54997,2810,23348,4681,685,27344,9462,1793,3600,720,58504,8601,5318,9378,10584,22898,23329,1794,26230,55296,154043,153090,5627,871,4233,81704,3486,57628,2597,1447,79924,57580,2257,7481,481,57463,125058,80005,2260,6622,7453,55450,8660,5903,57584,3627,10718,27018,100506013,57480,6001,142679,9966,3082,160518,57221,114336,10160,9235,9826,2059,3843,152189,10673,402,23362,2621,6000,654,4734,5523,9912,84144,26575,219527,1124,6324,23263,5580,8614,27094,23678,6446,57186,84632,27075,26034,285590,54206,23158,10253,83666,92597,7424,10451,54453,116984,64283,51232,9693,23101,9265,55616,22821,116986,9749,9743,10399,22943,2822,57761,85440,2200,2906,652,9882,57572,4325,493,5569 ARHGAP26,PHACTR3,CACNG3,PPP4R4,FGF13,RECK,DNAJC3,VAMP8,HDGFL3,NPM1,DOCK3,FAM13A,SKI,ARHGEF10L,ADPRHL1,BAG3,SIPA1L2,TYMP,PPP1R26,KCNAB1,HPS1,KCNS3,PPP2R2B,PCOLCE2,RCAN3,RAPGEF5,SLIT2,RASGRP1,PDGFRB,TBC1D8,TNK2,KCNIP3,SESN2,COL4A3,WISP3,TGFA,LRRK2,ELMOD1,PRKAR2B,FGF17,SGK2,SERGEF,ARHGEF26,INHBC,KCNMB4,GPRC5B,NCKAP1L,RASGRF2,ADRB1,BMP1,ARHGAP28,SEMA3C,SERPINI1,NRP1,TNFSF4,SPOCK3,KCNV1,RGS16,ALOX5AP,FN1,STXBP5L,LGALS3,TBC1D1,OPHN1,GPSM2,SPINK5,HPCAL4,GRPEL2,EFEMP1,IL17D,CHN1,RALGPS2,FRY,SEMA4F,FLRT3,SRGAP1,PRKG1,LRP6,NCAM1,DENND1C,GFRA1,BOD1,FGFR4,BDNF,ATP5IF1,MSTN,TBC1D8B,RAPGEF4,GPSM1,SPATA13,PACSIN3,OBSCN,PLCB1,TBC1D2,MMP15,ADGRB3,THBS4,CSF1,SH3BP4,INHBE,IQSEC2,SEMA3A,TESC,SFN,DOCK9,NBL1,BTC,PCSK1N,RASAL2,DOCK1,IL15,C4A,ARHGAP22,RGS20,PKP2,NRXN1,COLEC10,DENND3,TBC1D30,DOCK2,TIAM2,TBC1D19,CNKSR3,DAB2IP,PROS1,SERPINH1,MET,DOCK8,IGFBP3,DPP10,GAPDH,CSN2,ADM2,PREX1,FGF12,WNT11,ATP1B1,AMIGO1,TBC1D16,DOCK5,FGFR1,SNCA,WARS,CAMK2N1,IRS2,RANBP2,ARHGAP21,CXCL10,NRG3,BEX3,APELA,PLEKHG1,RGS10,DUSP19,TNFSF15,HGF,DENND5B,ARFGEF3,CGB2,FARP1,IL32,ARHGEF11,EPS8,IPO5,CMTM8,TNFSF13B,ARL2,PSD3,GAS6,RGS7,BMP6,NEDD4,PPP2R3A,ARHGAP44,SYDE2,RGS17,LRRC55,CHN2,SCN1B,MCF2L,PRKCD,STC2,KCNMB3,SGK3,SGK1,RALGAPA2,AFAP1L2,TSPAN13,IPCEF1,SH3PXD2B,ERRFI1,TBC1D9,SPRY2,PARP9,MOB1B,VEGFC,VAV3,RIN2,ARAP2,ARHGEF28,CRIM1,RAPGEF2,MCF2L2,CYTH3,ASAP3,RASA3,AGAP2,PHACTR2,ARHGAP32,RACK1,DKK1,GPLD1,TRIB3,DOCK7,FBN1,GRIN2D,BMP4,TBC1D4,DOCK6,MMP16,ATP2B4,PKIA GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity 0.00034660488872675 -7.96732507597338 20 8 0.00476190476190476 1680 17224 2591,2589,11226,79695,114805,64409,374378,79623 GALNT3,GALNT1,GALNT6,GALNT12,GALNT13,GALNT17,GALNT18,GALNT14 GO:0017048 Rho GTPase binding 0.000417523376861014 -7.78117002275941 169 31 0.018452380952381 1680 17224 5058,10451,10160,64283,9826,1793,57144,23101,29091,120892,2059,57580,221178,84033,5585,1794,9912,26230,26084,55160,85440,29941,5924,23263,57480,57522,219790,128239,8531,114793,57531 PAK1,VAV3,FARP1,ARHGEF28,ARHGEF11,DOCK1,PAK5,MCF2L2,STXBP6,LRRK2,EPS8,PREX1,SPATA13,OBSCN,PKN1,DOCK2,ARHGAP44,TIAM2,ARHGEF26,ARHGEF10L,DOCK7,PKN3,RASGRF2,MCF2L,PLEKHG1,SRGAP1,RTKN2,IQGAP3,YBX3,FMNL2,HACE1 GO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding 0.000444716550345319 -7.71807344426289 661 91 0.0541666666666667 1680 17224 64764,29842,5013,2625,6777,255877,1050,7227,64376,8320,29841,604,5452,2115,2023,2735,7080,30818,468,4212,2649,11166,579,4774,4779,10413,100271849,467,23314,474,10538,53335,55509,4088,9242,22806,3131,60468,148523,688,1628,1746,63973,3219,29942,4208,64919,11279,860,4601,55893,23051,5966,122953,5324,51222,6304,4825,93986,2624,168620,4609,6720,7020,8531,148979,4091,56033,1052,30062,4487,3174,2104,3164,84159,9516,9935,639,7545,1051,64324,5325,138151,26508,7494,3239,5083,26257,64754,10736,1649 CREB3L2,TFCP2L1,OTX1,GATA3,STAT5B,BCL6B,CEBPA,TRPS1,IKZF5,EOMES,GRHL1,BCL6,POU2F2,ETV1,ENO1,GLI1,NKX2-1,KCNIP3,ATF4,MEIS2,NR6A1,SOX21,NKX3-2,NFIA,NFE2L1,YAP1,MEF2B,ATF3,SATB2,ATOH1,BATF,BCL11A,BATF3,SMAD3,MSC,IKZF3,HLF,BACH2,CIART,KLF5,DBP,DLX2,NEUROG2,HOXB9,PURG,MEF2C,BCL11B,KLF8,RUNX2,MXI1,ZNF395,ZHX3,REL,JDP2,PLAG1,ZNF219,SATB1,NKX6-1,FOXP2,GATA2,BHLHA15,MYC,SREBF1,TFAP2A,YBX3,GLIS1,SMAD6,BARX1,CEBPD,RAX,MSX1,HNF4G,ESRRG,NR4A1,ARID5B,LITAF,MAFB,PRDM1,ZIC1,CEBPB,NSD1,PLAGL1,NACC2,HEYL,XBP1,HOXD13,PAX9,NKX2-8,SMYD3,SIX2,DDIT3 GO:0016301 kinase activity 0.000471112406942073 -7.66041383649368 855 113 0.0672619047619048 1680 17224 2042,685,152110,4598,90,1147,6777,4916,5596,2870,5578,780,8428,5891,10290,7049,6196,83694,140469,92,2051,4233,5567,5159,10188,2241,91807,4139,5163,130399,5208,27133,120892,53354,5588,93,8822,4919,10110,2444,157,2260,260425,27010,8660,9149,203,5579,5754,10769,2081,84451,5603,5287,3082,657,8829,5602,22983,7301,5563,26524,23043,8444,659,57144,9748,5585,2047,2202,3480,118788,57143,5580,5592,23678,6446,5593,80216,375449,6850,2242,5210,2264,5058,123688,51232,4354,1944,81788,84033,205,55437,8476,79834,9261,57761,2268,29941,57161,10000,5608,4355,3099,79858,283209,138429,1740,3098,79705,129607,51776,79646 EPHA3,BTC,NEK10,MVK,ACVR1,CHUK,STAT5B,NTRK3,MAPK4,GRK6,PRKCA,DDR1,STK24,MOK,SPEG,TGFBR3,RPS6KA2,RPS6KL1,MYO3B,ACVR2A,EPHB6,MET,PRKACB,PDGFRB,TNK2,FER,MYLK3,MARK1,PDK1,ACVR1C,PFKFB2,KCNH5,LRRK2,PANK1,PRKCQ,ACVR2B,FGF17,ROR1,SGK2,FRK,GRK3,FGFR1,MAGI3,TPK1,IRS2,DYRK1B,AK1,PRKCB,PTK7,PLK2,ERN1,MAP3K21,MAPK13,PIK3C2B,HGF,BMPR1A,NRP1,MAPK10,MAST1,TYRO3,PRKAA2,LATS2,TNIK,DYRK3,BMPR2,PAK5,SLK,PKN1,EPHB1,EFEMP1,IGF1R,PIK3AP1,ADCK1,PRKCD,PRKG1,SGK3,SGK1,PRKG2,ALPK1,MAST4,SYK,FES,PFKFB4,FGFR4,PAK1,HYKK,CRIM1,MPP1,EFNA3,NUAK2,OBSCN,AK4,STRADB,CDC42BPA,PEAK1,MAPKAPK2,TRIB3,FGR,PKN3,PELI2,AKT3,MAP2K6,MPP2,HK2,NEK11,PGM2L1,PIP5KL1,DLG2,HK1,LRRK1,CMPK2,MAP3K20,PANK3 GO:0000982 transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding 0.000476614170250715 -7.6488032617846 416 62 0.0369047619047619 1680 17224 64764,64919,11279,860,5324,122953,5013,2625,6777,1050,51222,4825,93986,29841,2624,4609,6720,57593,7020,5452,2672,2115,2023,6591,1052,30062,30818,468,4212,4487,3174,2649,11166,579,3164,4774,9516,9935,100271849,467,23314,639,474,23414,10538,7545,53335,55509,1879,1051,3131,138151,26508,26137,688,3239,1628,26257,10736,1649,3169,4208 CREB3L2,BCL11B,KLF8,RUNX2,PLAG1,JDP2,OTX1,GATA3,STAT5B,CEBPA,ZNF219,NKX6-1,FOXP2,GRHL1,GATA2,MYC,SREBF1,EBF4,TFAP2A,POU2F2,GFI1,ETV1,ENO1,SNAI2,CEBPD,RAX,KCNIP3,ATF4,MEIS2,MSX1,HNF4G,NR6A1,SOX21,NKX3-2,NR4A1,NFIA,LITAF,MAFB,MEF2B,ATF3,SATB2,PRDM1,ATOH1,ZFPM2,BATF,ZIC1,BCL11A,BATF3,EBF1,CEBPB,HLF,NACC2,HEYL,ZBTB20,KLF5,HOXD13,DBP,NKX2-8,SIX2,DDIT3,FOXA1,MEF2C GO:0005509 calcium ion binding 0.000497068796118356 -7.60678211867384 698 95 0.056547619047619 1680 17224 5321,8448,1951,54947,91683,3949,3709,821,255928,9378,92737,27445,83872,56884,23413,5099,54749,5358,85477,10382,11328,4753,10497,5627,9353,10125,25801,30818,64168,1447,23670,114327,79825,2161,444,2009,6622,2934,5167,147372,5066,649,57333,123036,50859,5723,54510,54550,57088,9620,1047,55784,4038,6402,64084,2621,51440,79056,5523,56122,2202,30845,1829,23158,55033,54795,60437,57575,54885,9693,777,80258,8642,7436,80267,5638,6262,5357,715,23236,4255,57493,2591,56129,79633,2200,7060,2195,4147,1015,51162,1000,54997,7178,7093 PLA2G4A,DOC2A,CELSR3,LPCAT2,SYT12,LDLR,ITPR2,CANX,SYT14,NRXN1,DNER,PCLO,HMCN1,FSTL5,NCS1,PCDH7,EPDR1,PLS3,SCIN,TUBB4A,FKBP9,NELL2,UNC13B,PROS1,SLIT2,RASGRP1,GCA,KCNIP3,NECAB1,CSN2,CEMIP2,EFHC1,EFCC1,F12,ASPH,EML1,SNCA,GSN,ENPP1,CCBE1,PAM,BMP1,RCN3,TC2N,SPOCK3,PSPH,PCDH18,NECAB2,PLSCR4,CELSR1,CLGN,MCTP2,LRP4,SELL,CLSTN2,GAS6,HPCAL4,PRRG4,PPP2R3A,PCDHB14,EFEMP1,EHD3,DSG2,TBC1D9,FKBP14,TRPM4,CDH26,PCDH10,TBC1D8B,RAPGEF2,CACNA1E,EFHC2,DCHS1,VLDLR,EDEM3,PRRG1,RYR2,PLS1,C1R,PLCB1,MGMT,HEG1,GALNT3,PCDHB7,FAT4,FBN1,THBS4,FAT1,MATN2,CDH17,EGFL7,CDH2,TESC,TPT1,TLL2 GO:0046983 protein dimerization activity 0.000503715319095153 -7.59349929254202 1280 160 0.0952380952380952 1680 17224 90,2898,10859,3512,2625,4869,1050,1488,6777,253559,18,51429,54033,22807,84679,23475,1890,3781,51166,29841,3257,3078,2947,7099,2023,9353,10125,2731,468,2649,120892,665,100271849,10413,1380,57491,114088,5167,10855,2081,153,2073,22876,7168,63973,58528,92421,51084,4208,7301,833,9620,23051,122953,9748,26272,122622,134266,53342,10388,253461,56952,79955,4609,23767,6720,57593,4040,664,58494,3156,11043,60437,93974,2660,100129654,2948,9455,2194,3092,9935,64077,6875,23236,202559,6456,1435,26508,1000,54997,4681,3397,119,1147,5596,55607,869,10247,440,153090,9312,25801,2617,8322,4597,57502,467,25776,474,83700,2260,7453,4088,9242,22806,2995,2633,348093,3673,25937,84451,3248,54937,3082,657,4281,5723,23462,10178,4601,2888,4038,875,5028,7164,654,79187,93986,3157,168620,2690,8614,7020,5593,57186,2946,3164,10399,10333,1879,1051,3399,7015,143098,138151,7494,1649,8945,9619,2040 ACVR1,GRIK2,LILRB1,JCHAIN,GATA3,NPM1,CEBPA,CTBP2,STAT5B,CADM2,ABAT,SNX9,RBM11,IKZF2,SLC9A7,QPRT,TYMP,KCNN2,AADAT,GRHL1,HPS1,CFHR1,GSTM3,TLR4,ENO1,SLIT2,RASGRP1,GLDC,ATF4,NR6A1,LRRK2,BNIP3L,MEF2B,YAP1,CR2,AHRR,TRIM9,ENPP1,HPSE,ERN1,ADRB1,ERCC5,INPP5F,TPM1,NEUROG2,RRAGD,CHMP4C,CRYL1,MEF2C,TYRO3,CARS,CELSR1,ZHX3,JDP2,SLK,FBXO4,ADSSL1,GRPEL2,IL17D,SYCP2,ZBTB38,PRTFDC1,PDZD7,MYC,FLRT3,SREBF1,EBF4,LRP6,BNIP3,JAM2,HMGCR,MID2,CDH26,ATP5IF1,MSTN,TCF24,GSTM4,HOMER2,FASN,HIP1,MAFB,LHPP,TAF4B,PLCB1,KHDRBS2,SH3GL2,CSF1,HEYL,CDH2,TESC,NBL1,ID1,ADD2,CHUK,MAPK4,PPP1R9A,CBLN1,RIDA,ASNS,DAB2IP,KCNB2,GCA,GARS,FZD4,MVD,NLGN4X,ATF3,CBY1,ATOH1,JAM3,FGFR1,WARS,SMAD3,MSC,IKZF3,GYPC,GBP1,RBPMS2,ITGA2,WWTR1,MAP3K21,HPGD,SOHLH2,HGF,BMPR1A,MID1,PSPH,HEY1,TENM1,MXI1,GRB14,LRP4,CBS,P2RY1,TPD52L1,BMP6,FSD1,FOXP2,HMGCS1,BHLHA15,GHR,STC2,TFAP2A,PRKG2,RALGAPA2,GSTM2,NR4A1,RACK1,TLR6,EBF1,CEBPB,ID3,TERT,MPP7,NACC2,XBP1,DDIT3,BTRC,ABCG1,STOM GO:0001012 RNA polymerase II regulatory region DNA binding 0.000516537440017289 -7.56836278409891 664 91 0.0541666666666667 1680 17224 64764,29842,5013,2625,6777,255877,1050,7227,64376,8320,29841,604,5452,2115,2023,2735,7080,30818,468,4212,2649,11166,579,4774,4779,10413,100271849,467,23314,474,10538,53335,55509,4088,9242,22806,3131,60468,148523,688,1628,1746,63973,3219,29942,4208,64919,11279,860,4601,55893,23051,5966,122953,5324,51222,6304,4825,93986,2624,168620,4609,6720,7020,8531,148979,4091,56033,1052,30062,4487,3174,2104,3164,84159,9516,9935,639,7545,1051,64324,5325,138151,26508,7494,3239,5083,26257,64754,10736,1649 CREB3L2,TFCP2L1,OTX1,GATA3,STAT5B,BCL6B,CEBPA,TRPS1,IKZF5,EOMES,GRHL1,BCL6,POU2F2,ETV1,ENO1,GLI1,NKX2-1,KCNIP3,ATF4,MEIS2,NR6A1,SOX21,NKX3-2,NFIA,NFE2L1,YAP1,MEF2B,ATF3,SATB2,ATOH1,BATF,BCL11A,BATF3,SMAD3,MSC,IKZF3,HLF,BACH2,CIART,KLF5,DBP,DLX2,NEUROG2,HOXB9,PURG,MEF2C,BCL11B,KLF8,RUNX2,MXI1,ZNF395,ZHX3,REL,JDP2,PLAG1,ZNF219,SATB1,NKX6-1,FOXP2,GATA2,BHLHA15,MYC,SREBF1,TFAP2A,YBX3,GLIS1,SMAD6,BARX1,CEBPD,RAX,MSX1,HNF4G,ESRRG,NR4A1,ARID5B,LITAF,MAFB,PRDM1,ZIC1,CEBPB,NSD1,PLAGL1,NACC2,HEYL,XBP1,HOXD13,PAX9,NKX2-8,SMYD3,SIX2,DDIT3 GO:0022890 inorganic cation transmembrane transporter activity 0.000547188860840526 -7.51071654851422 596 83 0.0494047619047619 1680 17224 10368,2898,10396,55283,3709,114134,785,84679,23413,7881,1138,3781,5002,3790,7220,54805,154091,140738,6326,27112,92270,6328,9312,2823,30818,6520,285335,64116,27133,475,56704,8973,81894,3752,481,23516,27345,540,3755,41,150159,160518,27012,55129,57156,6331,6536,6334,90423,2621,6507,9990,3749,90550,255231,3761,219527,7782,6324,783,27094,55117,79815,728215,85414,490,56901,54795,30061,3786,206358,777,22821,6262,2900,55002,60598,11182,2906,7222,781,493,478 CACNG3,GRIK2,ATP8A1,MCOLN3,ITPR2,SLC2A13,CACNB4,SLC9A7,NCS1,KCNAB1,CHRNA5,KCNN2,SLC22A18,KCNS3,TRPC1,CNNM2,SLC2A12,TMEM37,SCN2A,FAM155B,ATP6AP1L,SCN3A,KCNB2,GPM6A,KCNIP3,SLC3A2,SLC9C1,SLC39A8,KCNH5,ATOX1,JPH1,CHRNA6,SLC25A28,KCND3,ATP1B1,SLC39A14,KCNMB4,ATP7B,KCNG1,ASIC1,SLC9B1,DENND5B,KCNV1,ANO10,TMEM63C,SCN5A,SLC6A9,SCN8A,ATP6V1E2,GAS6,SLC1A3,SLC12A6,KCNC4,MCU,MCOLN2,KCNJ4,LRRC55,SLC30A4,SCN1B,CACNB2,KCNMB3,SLC6A15,NIPAL2,FAM155A,SLC45A3,ATP2B1,NDUFA4L2,TRPM4,SLC40A1,KCNQ3,SLC36A1,CACNA1E,RASA3,RYR2,GRIK4,TMCO3,KCNK15,SLC2A6,GRIN2D,TRPC3,CACNA2D1,ATP2B4,ATP1A3 GO:0036094 small molecule binding 0.000627902284547142 -7.37312600145755 2448 284 0.169047619047619 1680 17224 90,10396,51175,1488,63827,5578,5881,16,8428,5891,9531,1768,5911,25837,2731,130399,120892,5577,1244,93,2770,5167,10769,540,226,56898,5603,148252,144132,51084,833,26524,241,6334,9748,1718,29899,6507,122622,26038,134266,57143,200558,5592,10960,80216,55137,375449,3156,4860,4651,11069,2194,6262,10577,8476,1203,55760,57494,29941,6713,1717,162394,7222,387751,6296,2042,92170,26052,29984,4430,1147,5596,2870,10584,780,114112,10290,440,8564,134429,5144,5874,379,1767,91807,2597,2617,5163,5208,51700,53354,107,5588,481,23682,57205,260425,2260,6622,953,64208,5579,6999,84451,5066,3248,5033,657,5602,27314,4642,23464,10079,402,875,3800,5028,5585,2047,348751,10265,3157,8435,23678,5593,85007,79659,4646,55964,2242,83666,5210,54795,26873,217,51560,9693,205,23250,2977,57761,3399,2268,5352,2775,10000,114879,79858,138429,3098,79705,129607,493,478,349565,2180,4598,3798,7358,445,18,3709,8153,10382,6196,51166,7881,9465,54805,7220,2051,5159,5567,51062,10188,4139,83667,10257,23670,4919,10110,27244,157,9149,203,10827,8974,2081,5287,58528,84706,7301,5563,55034,860,11149,9886,284716,65997,26227,116835,56952,253461,1938,3480,23461,10846,222537,112,4846,2264,5058,23433,11001,84033,55437,197257,9261,3099,11031,79646,152110,4916,23046,91351,1592,10247,83694,2172,140469,92,22989,2272,4233,3306,1491,2241,7846,4597,2444,79739,64850,7453,27010,5754,2633,5413,22983,23043,8444,659,57144,54622,338323,51655,5580,30845,23551,2963,59,6446,5106,22800,6850,490,9645,5865,389643,55753,81788,116986,4141,79834,9227,23576,390,5608,2329,55605,2669,51776,23095,9619 ACVR1,ATP8A1,TUBE1,CTBP2,BCAN,PRKCA,RAC3,AARS,STK24,MOK,BAG3,DNAH6,RAP2A,RAB26,GLDC,ACVR1C,LRRK2,PRKAR2B,ABCC2,ACVR2B,GNAI1,ENPP1,PLK2,ATP7B,ALDOA,BDH2,MAPK13,DIRAS1,DNHD1,CRYL1,CARS,LATS2,ALOX5AP,SCN8A,SLK,DHCR24,GPSM2,SLC1A3,ADSSL1,CHD5,GRPEL2,ADCK1,APLF,PRKG1,LMAN2,ALPK1,FIGN,MAST4,HMGCR,PNP,MYO10,RAPGEF4,FASN,RYR2,NPC2,CDC42BPA,CLN5,DHX32,RIMKLB,PKN3,SQLE,DHCR7,SLFN5,TRPC3,GVINP1,ACSM3,EPHA3,MTG1,DNM3,RHOD,MYO1B,CHUK,MAPK4,GRK6,COLEC10,DDR1,TXNRD3,SPEG,ASNS,KMO,STARD4,PDE4D,RAB27B,ARL4D,DNAH5,MYLK3,GAPDH,GARS,PDK1,PFKFB2,CYB5R2,PANK1,ADCY1,PRKCQ,ATP1B1,RAB38,ATP10D,MAGI3,FGFR1,SNCA,ENTPD1,POPDC3,PRKCB,TDO2,MAP3K21,PAM,HPGD,P4HA1,BMPR1A,MAPK10,RAB30,MYO1D,GCAT,ATP9A,ARL2,CBS,KIF5C,P2RY1,PKN1,EPHB1,FTCDNL1,IRX5,HMGCS1,SOAT2,SGK3,PRKG2,PHYKPL,DYNC2H1,MYO6,SEPT3,FES,PARP9,PFKFB4,TRPM4,OPLAH,ALDH2,RAB6B,RAPGEF2,AK4,ATP11A,GUCY1A2,TRIB3,ID3,FGR,PLOD2,GNAO1,AKT3,OSBPL5,NEK11,PIP5KL1,HK1,LRRK1,CMPK2,ATP2B4,ATP1A3,NMNAT3,ACSL1,MVK,KIF5A,UGDH,ASS1,ABAT,ITPR2,RND2,TUBB4A,RPS6KA2,AADAT,KCNAB1,AKAP7,CNNM2,TRPC1,EPHB6,PDGFRB,PRKACB,ATL1,TNK2,MARK1,SESN2,ABCC4,CEMIP2,ROR1,SGK2,SESN1,GRK3,DYRK1B,AK1,FAM114A2,P4HA2,ERN1,PIK3C2B,RRAGD,GPT2,TYRO3,PRKAA2,MOCOS,RUNX2,BVES,RHOBTB1,RIMKLA,RASL11B,PHGDH,HSPA12B,PRTFDC1,ZBTB38,EEF2,IGF1R,ABCA5,PDE10A,HS3ST5,ADCY6,NOS3,FGFR4,PAK1,RHOQ,SLC27A2,OBSCN,STRADB,LDHD,MAPKAPK2,HK2,RAB31,PANK3,NEK10,NTRK3,KIF21B,DDX60L,CYP26A1,RIDA,RPS6KL1,FABP6,MYO3B,ACVR2A,MYH15,FHIT,MET,HSPA2,CTH,FER,TUBA1A,MVD,FRK,TTLL7,ETNPPL,WARS,TPK1,PTK7,GBP1,SEPT5,MAST1,TNIK,DYRK3,BMPR2,PAK5,ARL15,NLRP14,RASD1,PRKCD,EHD3,RASD2,GTF2F2,ACTA2,SGK1,PCK2,RRAS2,SYK,ATP2B1,MICAL2,RAB3B,NUGGC,OGDHL,NUAK2,AGAP2,MARS,PEAK1,LRAT,DDAH1,RND3,MAP2K6,FMO4,KIF21A,GEM,MAP3K20,KIF1B,ABCG1 GO:0004675 transmembrane receptor protein serine/threonine kinase activity 0.000668328938080822 -7.31073008335101 17 7 0.00416666666666667 1680 17224 92,657,93,90,7049,659,130399 ACVR2A,BMPR1A,ACVR2B,ACVR1,TGFBR3,BMPR2,ACVR1C GO:0005085 guanyl-nucleotide exchange factor activity 0.000689244159713323 -7.27991498149007 323 50 0.0297619047619048 1680 17224 685,10160,9826,1793,2059,23362,1795,22898,1794,26230,55160,55103,3257,23263,79958,4233,4684,2674,9771,81704,10125,5159,2264,54453,10451,64283,9693,23101,9265,11069,57580,221178,84033,8822,80005,26297,2260,26084,8660,85440,5924,57480,153,2906,3082,23096,57572,23348,160518,57221 BTC,FARP1,ARHGEF11,DOCK1,EPS8,PSD3,DOCK3,DENND3,DOCK2,TIAM2,ARHGEF10L,RALGPS2,HPS1,MCF2L,DENND1C,MET,NCAM1,GFRA1,RAPGEF5,DOCK8,RASGRP1,PDGFRB,FGFR4,RIN2,VAV3,ARHGEF28,RAPGEF2,MCF2L2,CYTH3,RAPGEF4,PREX1,SPATA13,OBSCN,FGF17,DOCK5,SERGEF,FGFR1,ARHGEF26,IRS2,DOCK7,RASGRF2,PLEKHG1,ADRB1,GRIN2D,HGF,IQSEC2,DOCK6,DOCK9,DENND5B,ARFGEF3 GO:0019900 kinase binding 0.000710444555238216 -7.24961964973077 688 93 0.0553571428571429 1680 17224 2042,5071,29984,5611,5318,119,4869,1050,4916,5596,1488,780,5881,6497,8153,9465,51339,26960,153090,9832,4082,2051,4233,282973,80014,3556,5159,9846,468,5208,287,5777,5577,481,4919,1832,23331,2260,7453,4088,55450,8660,10718,5795,51704,5579,84451,142679,148252,8829,143384,84978,7301,6331,55857,2888,9886,4038,2621,5585,2047,1938,3480,5580,2690,6720,59,112,54206,10253,6850,92597,2264,23433,6262,23286,5151,10399,8631,5788,9261,1051,57761,2268,390,257144,5608,55353,1740,9172,1000,2810,5569 EPHA3,PRKN,RHOD,DNAJC3,PKP2,ADD2,NPM1,CEBPA,NTRK3,MAPK4,CTBP2,DDR1,RAC3,SKI,RND2,AKAP7,DACT1,NBEA,DAB2IP,JAKMIP2,MARCKS,EPHB6,MET,JAKMIP3,WWC2,IL1RAP,PDGFRB,GAB2,ATF4,PFKFB2,ANK2,PTPN6,PRKAR2B,ATP1B1,ROR1,DSP,TTC28,FGFR1,WARS,SMAD3,CAMK2N1,IRS2,NRG3,PTPRJ,GPRC5B,PRKCB,MAP3K21,DUSP19,DIRAS1,NRP1,CACUL1,FRMD5,TYRO3,SCN5A,KIZ,GRB14,RHOBTB1,LRP4,GAS6,PKN1,EPHB1,EEF2,IGF1R,PRKCD,GHR,SREBF1,ACTA2,ADCY6,ERRFI1,SPRY2,SYK,MOB1B,FGFR4,RHOQ,RYR2,WWC1,PDE8A,RACK1,SKAP1,PTPRC,MAPKAPK2,CEBPB,TRIB3,FGR,RND3,GCSAM,MAP2K6,LAPTM4B,DLG2,MYOM2,CDH2,SFN,PKIA GO:0016773 phosphotransferase activity, alcohol group as acceptor 0.000719790578221924 -7.23655025184385 785 104 0.0619047619047619 1680 17224 2042,685,152110,4598,90,1147,6777,4916,5596,2870,5578,780,8428,5891,10290,7049,6196,83694,140469,92,2051,4233,5567,5159,10188,2241,91807,4139,5163,130399,5208,27133,120892,53354,5588,93,8822,4919,10110,2444,157,2260,8660,9149,5579,5754,10769,2081,84451,5603,5287,3082,657,8829,5602,22983,7301,5563,26524,23043,8444,659,57144,9748,5585,2047,2202,3480,118788,57143,5580,5592,23678,6446,5593,80216,375449,6850,2242,5210,2264,5058,123688,51232,1944,81788,84033,55437,8476,79834,9261,2268,29941,57161,10000,5608,3099,79858,283209,138429,3098,79705,51776,79646 EPHA3,BTC,NEK10,MVK,ACVR1,CHUK,STAT5B,NTRK3,MAPK4,GRK6,PRKCA,DDR1,STK24,MOK,SPEG,TGFBR3,RPS6KA2,RPS6KL1,MYO3B,ACVR2A,EPHB6,MET,PRKACB,PDGFRB,TNK2,FER,MYLK3,MARK1,PDK1,ACVR1C,PFKFB2,KCNH5,LRRK2,PANK1,PRKCQ,ACVR2B,FGF17,ROR1,SGK2,FRK,GRK3,FGFR1,IRS2,DYRK1B,PRKCB,PTK7,PLK2,ERN1,MAP3K21,MAPK13,PIK3C2B,HGF,BMPR1A,NRP1,MAPK10,MAST1,TYRO3,PRKAA2,LATS2,TNIK,DYRK3,BMPR2,PAK5,SLK,PKN1,EPHB1,EFEMP1,IGF1R,PIK3AP1,ADCK1,PRKCD,PRKG1,SGK3,SGK1,PRKG2,ALPK1,MAST4,SYK,FES,PFKFB4,FGFR4,PAK1,HYKK,CRIM1,EFNA3,NUAK2,OBSCN,STRADB,CDC42BPA,PEAK1,MAPKAPK2,FGR,PKN3,PELI2,AKT3,MAP2K6,HK2,NEK11,PGM2L1,PIP5KL1,HK1,LRRK1,MAP3K20,PANK3 GO:0042802 identical protein binding 0.000730229027961368 -7.2221523360936 1670 201 0.119642857142857 1680 17224 4598,90,2898,3949,8495,445,10859,3512,4869,1050,1488,253559,18,51429,54033,22807,84679,23475,1890,3781,51166,29841,3078,3690,2947,29993,2023,9353,10125,2731,51062,10188,2649,10486,2706,120892,665,27351,1380,60485,5831,114088,5167,4685,226,2081,7132,649,2073,22876,7168,92421,51084,833,2335,23051,84959,26272,9748,29899,122622,134266,53342,253461,56952,3480,118788,79955,590,23767,338761,4040,664,64115,6812,3156,11043,93974,60437,2660,6775,2948,9455,2194,2274,3092,6262,9672,9935,64077,10567,8476,221935,23236,202559,10458,130271,6456,119391,115548,1435,26508,23677,1000,54997,2810,4681,5071,154810,3397,5362,119,1147,115207,5596,869,55607,1496,10247,7098,440,79047,604,153090,4082,2272,4233,1491,25801,2597,2617,10076,29997,8322,4597,57502,7431,467,25776,64850,83700,2260,7453,6622,4088,5795,22806,2995,27018,6999,2633,348093,51225,25937,84451,5033,3248,54937,3082,657,4281,284252,5723,10178,6092,2888,4038,875,7164,90550,93986,79187,3157,168620,8614,2690,7020,5593,85007,55964,2098,4091,30061,9099,2946,10399,10333,3198,3953,9454,5788,1051,7015,138151,2200,9069,7494,79705,1649,9619,2040 MVK,ACVR1,GRIK2,LDLR,PPFIBP2,ASS1,LILRB1,JCHAIN,NPM1,CEBPA,CTBP2,CADM2,ABAT,SNX9,RBM11,IKZF2,SLC9A7,QPRT,TYMP,KCNN2,AADAT,GRHL1,CFHR1,ITGB3,GSTM3,PACSIN1,ENO1,SLIT2,RASGRP1,GLDC,ATL1,TNK2,NR6A1,CAP2,GJB2,LRRK2,BNIP3L,DESI1,CR2,SAV1,PYCR1,TRIM9,ENPP1,NCAM2,ALDOA,ERN1,TNFRSF1A,BMP1,ERCC5,INPP5F,TPM1,CHMP4C,CRYL1,CARS,FN1,ZHX3,UBASH3B,FBXO4,SLK,GPSM2,ADSSL1,GRPEL2,IL17D,ZBTB38,PRTFDC1,IGF1R,PIK3AP1,PDZD7,BCHE,FLRT3,C1QL4,LRP6,BNIP3,VSIR,STXBP1,HMGCR,MID2,ATP5IF1,CDH26,MSTN,STAT4,GSTM4,HOMER2,FASN,FHL2,HIP1,RYR2,SDC3,MAFB,LHPP,RABAC1,CDC42BPA,SDK1,PLCB1,KHDRBS2,BAIAP2,PLEKHH2,SH3GL2,GSTO2,FCHO2,CSF1,HEYL,SH3BP4,CDH2,TESC,SFN,NBL1,PRKN,AMOTL1,ID1,PLXNA2,ADD2,CHUK,KCTD12,MAPK4,CBLN1,PPP1R9A,CTNNA2,RIDA,TLR3,ASNS,KCTD15,BCL6,DAB2IP,MARCKS,FHIT,MET,CTH,GCA,GAPDH,GARS,PTPRU,NOP53,FZD4,MVD,NLGN4X,VIM,ATF3,CBY1,ETNPPL,JAM3,FGFR1,WARS,SNCA,SMAD3,PTPRJ,IKZF3,GYPC,BEX3,TDO2,GBP1,RBPMS2,ABI3,WWTR1,MAP3K21,P4HA1,HPGD,SOHLH2,HGF,BMPR1A,MID1,KCTD1,PSPH,TENM1,ROBO2,GRB14,LRP4,CBS,TPD52L1,MCU,FOXP2,FSD1,HMGCS1,BHLHA15,STC2,GHR,TFAP2A,PRKG2,PHYKPL,SEPT3,ESD,SMAD6,SLC40A1,USP2,GSTM2,RACK1,TLR6,HOXA1,LEPR,HOMER3,PTPRC,CEBPB,TERT,NACC2,FBN1,CLDN12,XBP1,LRRK1,DDIT3,ABCG1,STOM GO:0035091 phosphatidylinositol binding 0.000733924208580814 -7.21710479274553 236 39 0.0232142857142857 1680 17224 29091,54477,4430,3709,51429,5217,9372,85477,1687,25851,57732,23263,154661,23678,153090,285590,134829,79958,29887,2242,51375,9846,4139,116984,4651,84725,117583,9265,10979,3092,9743,59338,23236,115548,114879,55353,5287,5337,221749 STXBP6,PLEKHA5,MYO1B,ITPR2,SNX9,PFN2,ZFYVE9,SCIN,GSDME,TECPR1,ZFYVE28,MCF2L,RUNDC3B,SGK3,DAB2IP,SH3PXD2B,CLVS2,DENND1C,SNX10,FES,SNX7,GAB2,MARK1,ARAP2,MYO10,PLEKHA8,PARD3B,CYTH3,FERMT2,HIP1,ARHGAP32,PLEKHA1,PLCB1,FCHO2,OSBPL5,LAPTM4B,PIK3C2B,PLD1,PXDC1 GO:0035591 signaling adaptor activity 0.00078468185200225 -7.15023220640522 82 18 0.0107142857142857 1680 17224 10451,6452,10580,8935,2888,9047,2059,10399,8631,1123,1124,143098,142679,90525,2887,84632,153090,9846 VAV3,SH3BP2,SORBS1,SKAP2,GRB14,SH2D2A,EPS8,RACK1,SKAP1,CHN1,CHN2,MPP7,DUSP19,SHF,GRB10,AFAP1L2,DAB2IP,GAB2 GO:0005516 calmodulin binding 0.000784727625486822 -7.15017387429338 198 34 0.0202380952380952 1680 17224 4642,6331,6004,5153,9495,4430,119,7082,3781,10497,22989,4082,128239,25827,4646,490,1491,4846,54795,93974,3786,4651,27133,107,84033,6262,6641,23236,9261,4133,7466,5924,2669,493 MYO1D,SCN5A,RGS16,PDE1B,AKAP5,MYO1B,ADD2,TJP1,KCNN2,UNC13B,MYH15,MARCKS,IQGAP3,FBXL2,MYO6,ATP2B1,CTH,NOS3,TRPM4,ATP5IF1,KCNQ3,MYO10,KCNH5,ADCY1,OBSCN,RYR2,SNTB1,PLCB1,MAPKAPK2,MAP2,WFS1,RASGRF2,GEM,ATP2B4 GO:0004713 protein tyrosine kinase activity 0.000804180262678444 -7.12568710660451 183 32 0.019047619047619 1680 17224 2042,2264,7301,2241,10188,685,8444,51232,1944,4916,6777,4919,8822,2047,79834,780,2444,2260,9149,2202,2268,3480,5608,5580,84451,3082,2051,4233,8829,6850,5159,2242 EPHA3,FGFR4,TYRO3,FER,TNK2,BTC,DYRK3,CRIM1,EFNA3,NTRK3,STAT5B,ROR1,FGF17,EPHB1,PEAK1,DDR1,FRK,FGFR1,DYRK1B,EFEMP1,FGR,IGF1R,MAP2K6,PRKCD,MAP3K21,HGF,EPHB6,MET,NRP1,SYK,PDGFRB,FES GO:0042169 SH2 domain binding 0.000859589162221609 -7.05905600120745 33 10 0.00595238095238095 1680 17224 3636,5777,10859,84632,10399,285590,9143,8631,202559,6850 INPPL1,PTPN6,LILRB1,AFAP1L2,RACK1,SH3PXD2B,SYNGR3,SKAP1,KHDRBS2,SYK GO:0001077 transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding 0.000884830357684587 -7.0301146175626 278 44 0.0261904761904762 1680 17224 64764,64919,860,5324,5013,2625,6777,1050,29841,2624,4609,6720,7020,57593,5452,2115,1052,30062,468,4212,3174,2649,11166,3164,4774,9516,9935,100271849,23314,474,10538,7545,1879,1051,3131,26508,3239,688,1628,26257,10736,3169,1649,4208 CREB3L2,BCL11B,RUNX2,PLAG1,OTX1,GATA3,STAT5B,CEBPA,GRHL1,GATA2,MYC,SREBF1,TFAP2A,EBF4,POU2F2,ETV1,CEBPD,RAX,ATF4,MEIS2,HNF4G,NR6A1,SOX21,NR4A1,NFIA,LITAF,MAFB,MEF2B,SATB2,ATOH1,BATF,ZIC1,EBF1,CEBPB,HLF,HEYL,HOXD13,KLF5,DBP,NKX2-8,SIX2,FOXA1,DDIT3,MEF2C GO:0022839 ion gated channel activity 0.000900066334718641 -7.01304209211313 335 51 0.0303571428571429 1680 17224 27012,55129,6331,57156,10368,2898,2561,6334,55283,2566,3709,2621,2570,3749,785,23413,255231,219527,3761,7881,1138,3781,6324,783,27094,3790,140738,6326,27112,728215,9312,6328,54795,30818,3786,27133,777,56704,2894,8973,94015,22821,6262,3752,2900,60598,27345,3755,41,2906,781 KCNV1,ANO10,SCN5A,TMEM63C,CACNG3,GRIK2,GABRB2,SCN8A,MCOLN3,GABRG2,ITPR2,GAS6,GABRR2,KCNC4,CACNB4,NCS1,MCOLN2,LRRC55,KCNJ4,KCNAB1,CHRNA5,KCNN2,SCN1B,CACNB2,KCNMB3,KCNS3,TMEM37,SCN2A,FAM155B,FAM155A,KCNB2,SCN3A,TRPM4,KCNIP3,KCNQ3,KCNH5,CACNA1E,JPH1,GRID1,CHRNA6,TTYH2,RASA3,RYR2,KCND3,GRIK4,KCNK15,KCNMB4,KCNG1,ASIC1,GRIN2D,CACNA2D1 GO:0015075 ion transmembrane transporter activity 0.00101280097396056 -6.89503554492341 900 116 0.0690476190476191 1680 17224 10368,2898,10396,55283,3709,114134,6542,785,10560,28232,84679,23413,7881,1138,3781,51310,6567,5002,347735,3790,7220,54805,154091,140738,6326,27112,92270,6328,9312,2823,30818,6520,10257,23507,285335,64116,119559,27133,475,56704,8973,81894,1244,3752,481,10052,94081,6541,23516,27345,540,3755,41,150159,160518,27012,55129,6331,57156,256987,6536,2561,6334,90423,2566,120103,2621,2570,6507,9990,81855,3749,90550,255231,3761,219527,7782,23657,6324,783,27094,220963,55117,79815,353189,728215,85414,490,54795,56901,30061,54020,3786,11001,206358,777,2894,6262,22821,94015,60598,55002,2900,84879,11182,8140,81796,2906,55356,6510,7222,117247,493,781,8501,478 CACNG3,GRIK2,ATP8A1,MCOLN3,ITPR2,SLC2A13,SLC7A2,CACNB4,SLC19A2,SLCO3A1,SLC9A7,NCS1,KCNAB1,CHRNA5,KCNN2,SLC22A17,SLC16A2,SLC22A18,SERINC2,KCNS3,TRPC1,CNNM2,SLC2A12,TMEM37,SCN2A,FAM155B,ATP6AP1L,SCN3A,KCNB2,GPM6A,KCNIP3,SLC3A2,ABCC4,LRRC8B,SLC9C1,SLC39A8,SFXN4,KCNH5,ATOX1,JPH1,CHRNA6,SLC25A28,ABCC2,KCND3,ATP1B1,GJC1,SFXN1,SLC7A1,SLC39A14,KCNMB4,ATP7B,KCNG1,ASIC1,SLC9B1,DENND5B,KCNV1,ANO10,SCN5A,TMEM63C,SERINC5,SLC6A9,GABRB2,SCN8A,ATP6V1E2,GABRG2,SLC36A4,GAS6,GABRR2,SLC1A3,SLC12A6,SFXN3,KCNC4,MCU,MCOLN2,KCNJ4,LRRC55,SLC30A4,SLC7A11,SCN1B,CACNB2,KCNMB3,SLC16A9,SLC6A15,NIPAL2,SLCO4C1,FAM155A,SLC45A3,ATP2B1,TRPM4,NDUFA4L2,SLC40A1,SLC37A1,KCNQ3,SLC27A2,SLC36A1,CACNA1E,GRID1,RYR2,RASA3,TTYH2,KCNK15,TMCO3,GRIK4,MFSD2A,SLC2A6,SLC7A5,SLCO5A1,GRIN2D,SLC22A15,SLC1A5,TRPC3,SLC16A10,ATP2B4,CACNA2D1,SLC43A1,ATP1A3 GO:0008047 enzyme activator activity 0.001023513946059 -6.88451352710427 522 73 0.043452380952381 1680 17224 23092,2258,9462,1793,58504,8601,10144,23329,1794,26230,55296,113622,57568,153090,26577,10125,3486,11138,120892,55531,57580,7481,481,125058,5903,57584,10718,51704,27018,3071,6001,142679,79822,8829,6004,241,2335,9515,9826,23216,4983,2621,6000,9912,84144,1123,26575,1124,5580,57522,57186,84632,285590,54206,23158,10253,92597,54453,10451,116984,54885,9693,55616,22821,116986,9743,10399,23236,55357,4324,577,9882,4325 ARHGAP26,FGF13,RASAL2,DOCK1,ARHGAP22,RGS20,FAM13A,TBC1D30,DOCK2,TIAM2,TBC1D19,ADPRHL1,SIPA1L2,DAB2IP,PCOLCE2,RASGRP1,IGFBP3,TBC1D8,LRRK2,ELMOD1,PREX1,WNT11,ATP1B1,TBC1D16,RANBP2,ARHGAP21,NRG3,GPRC5B,BEX3,NCKAP1L,RGS10,DUSP19,ARHGAP28,NRP1,RGS16,ALOX5AP,FN1,STXBP5L,ARHGEF11,TBC1D1,OPHN1,GAS6,RGS7,ARHGAP44,SYDE2,CHN1,RGS17,CHN2,PRKCD,SRGAP1,RALGAPA2,AFAP1L2,SH3PXD2B,ERRFI1,TBC1D9,SPRY2,MOB1B,RIN2,VAV3,ARAP2,TBC1D8B,RAPGEF2,ASAP3,RASA3,AGAP2,ARHGAP32,RACK1,PLCB1,TBC1D2,MMP15,ADGRB3,TBC1D4,MMP16 GO:0008324 cation transmembrane transporter activity 0.0010356502426256 -6.87272579578903 661 89 0.0529761904761905 1680 17224 10368,2898,10396,55283,3709,114134,6542,785,84679,23413,7881,1138,3781,5002,347735,3790,7220,54805,154091,140738,6326,27112,92270,6328,9312,2823,30818,6520,285335,64116,27133,475,56704,8973,81894,3752,481,6541,23516,27345,540,3755,41,150159,160518,27012,55129,57156,256987,6331,6536,6334,90423,120103,2621,6507,9990,3749,90550,255231,3761,219527,7782,6324,783,27094,55117,79815,728215,85414,490,56901,54795,30061,3786,206358,777,22821,6262,55002,2900,60598,11182,2906,6510,7222,781,493,478 CACNG3,GRIK2,ATP8A1,MCOLN3,ITPR2,SLC2A13,SLC7A2,CACNB4,SLC9A7,NCS1,KCNAB1,CHRNA5,KCNN2,SLC22A18,SERINC2,KCNS3,TRPC1,CNNM2,SLC2A12,TMEM37,SCN2A,FAM155B,ATP6AP1L,SCN3A,KCNB2,GPM6A,KCNIP3,SLC3A2,SLC9C1,SLC39A8,KCNH5,ATOX1,JPH1,CHRNA6,SLC25A28,KCND3,ATP1B1,SLC7A1,SLC39A14,KCNMB4,ATP7B,KCNG1,ASIC1,SLC9B1,DENND5B,KCNV1,ANO10,TMEM63C,SERINC5,SCN5A,SLC6A9,SCN8A,ATP6V1E2,SLC36A4,GAS6,SLC1A3,SLC12A6,KCNC4,MCU,MCOLN2,KCNJ4,LRRC55,SLC30A4,SCN1B,CACNB2,KCNMB3,SLC6A15,NIPAL2,FAM155A,SLC45A3,ATP2B1,NDUFA4L2,TRPM4,SLC40A1,KCNQ3,SLC36A1,CACNA1E,RASA3,RYR2,TMCO3,GRIK4,KCNK15,SLC2A6,GRIN2D,SLC1A5,TRPC3,CACNA2D1,ATP2B4,ATP1A3 GO:0015085 calcium ion transmembrane transporter activity 0.00108198476054131 -6.82895818318447 141 26 0.0154761904761905 1680 17224 54795,2823,10368,6520,777,56704,55283,6262,22821,3709,2621,785,23413,90550,255231,783,7220,2906,140738,27112,7222,728215,781,490,493,160518 TRPM4,GPM6A,CACNG3,SLC3A2,CACNA1E,JPH1,MCOLN3,RYR2,RASA3,ITPR2,GAS6,CACNB4,NCS1,MCU,MCOLN2,CACNB2,TRPC1,GRIN2D,TMEM37,FAM155B,TRPC3,FAM155A,CACNA2D1,ATP2B1,ATP2B4,DENND5B GO:0022836 gated channel activity 0.00110091380767378 -6.81161470979763 338 51 0.0303571428571429 1680 17224 27012,55129,6331,57156,10368,2898,2561,6334,55283,2566,3709,2621,2570,3749,785,23413,255231,219527,3761,7881,1138,3781,6324,783,27094,3790,140738,6326,27112,728215,9312,6328,54795,30818,3786,27133,777,56704,2894,8973,94015,22821,6262,3752,2900,60598,27345,3755,41,2906,781 KCNV1,ANO10,SCN5A,TMEM63C,CACNG3,GRIK2,GABRB2,SCN8A,MCOLN3,GABRG2,ITPR2,GAS6,GABRR2,KCNC4,CACNB4,NCS1,MCOLN2,LRRC55,KCNJ4,KCNAB1,CHRNA5,KCNN2,SCN1B,CACNB2,KCNMB3,KCNS3,TMEM37,SCN2A,FAM155B,FAM155A,KCNB2,SCN3A,TRPM4,KCNIP3,KCNQ3,KCNH5,CACNA1E,JPH1,GRID1,CHRNA6,TTYH2,RASA3,RYR2,KCND3,GRIK4,KCNK15,KCNMB4,KCNG1,ASIC1,GRIN2D,CACNA2D1 GO:0015175 neutral amino acid transmembrane transporter activity 0.00111254489372786 -6.80110519082539 34 10 0.00595238095238095 1680 17224 256987,6520,6536,23657,206358,347735,8140,120103,6510,8501 SERINC5,SLC3A2,SLC6A9,SLC7A11,SLC36A1,SERINC2,SLC7A5,SLC36A4,SLC1A5,SLC43A1 GO:0015631 tubulin binding 0.00115682114735529 -6.76207942581808 347 52 0.030952380952381 1680 17224 4642,161436,5071,26052,2258,3798,4430,3800,50810,23046,1780,57509,79187,26056,4130,283431,65055,140469,22989,9832,282973,4646,2242,2735,56896,11043,2597,400954,341019,4651,120892,55638,9638,114327,79739,2009,54627,23710,6622,4131,56271,28981,4133,57821,226,79884,55605,10891,23095,11178,4281,7178 MYO1D,EML5,PRKN,DNM3,FGF13,KIF5A,MYO1B,KIF5C,HDGFL3,KIF21B,DYNC1I1,MTUS1,FSD1,RAB11FIP5,MAP1A,GAS2L3,REEP1,MYO3B,MYH15,JAKMIP2,JAKMIP3,MYO6,FES,GLI1,DPYSL5,MID2,GAPDH,EML6,DCDC1,MYO10,LRRK2,SYBU,FEZ1,EFHC1,TTLL7,EML1,MAP10,GABARAPL1,SNCA,MAP1B,BEX4,IFT81,MAP2,CCDC181,ALDOA,MAP9,KIF21A,PPARGC1A,KIF1B,LZTS1,MID1,TPT1 GO:0005262 calcium channel activity 0.00119599099896942 -6.72878014942732 120 23 0.0136904761904762 1680 17224 54795,2823,10368,777,56704,55283,6262,22821,3709,2621,785,23413,90550,255231,783,7220,2906,140738,27112,7222,728215,781,160518 TRPM4,GPM6A,CACNG3,CACNA1E,JPH1,MCOLN3,RYR2,RASA3,ITPR2,GAS6,CACNB4,NCS1,MCU,MCOLN2,CACNB2,TRPC1,GRIN2D,TMEM37,FAM155B,TRPC3,FAM155A,CACNA2D1,DENND5B GO:0008017 microtubule binding 0.00129241276763182 -6.65124444505328 267 42 0.025 1680 17224 4642,161436,26052,2258,3798,4430,3800,50810,23046,1780,57509,79187,4130,283431,65055,140469,22989,9832,282973,4646,2242,2735,56896,11043,2597,400954,341019,4651,120892,55638,2009,54627,6622,4131,4133,57821,79884,55605,4281,11178,23095,7178 MYO1D,EML5,DNM3,FGF13,KIF5A,MYO1B,KIF5C,HDGFL3,KIF21B,DYNC1I1,MTUS1,FSD1,MAP1A,GAS2L3,REEP1,MYO3B,MYH15,JAKMIP2,JAKMIP3,MYO6,FES,GLI1,DPYSL5,MID2,GAPDH,EML6,DCDC1,MYO10,LRRK2,SYBU,EML1,MAP10,SNCA,MAP1B,MAP2,CCDC181,MAP9,KIF21A,MID1,LZTS1,KIF1B,TPT1 GO:0005089 Rho guanyl-nucleotide exchange factor activity 0.00137008540695701 -6.59288220024068 79 17 0.0101190476190476 1680 17224 10451,10160,64283,9826,1793,23101,2059,57580,221178,84033,1794,26084,26230,55160,23263,5924,57480 VAV3,FARP1,ARHGEF28,ARHGEF11,DOCK1,MCF2L2,EPS8,PREX1,SPATA13,OBSCN,DOCK2,ARHGEF26,TIAM2,ARHGEF10L,MCF2L,RASGRF2,PLEKHG1 GO:0017016 Ras GTPase binding 0.00137224689615166 -6.59130581240482 519 72 0.0428571428571429 1680 17224 23086,23312,685,1793,22898,1794,23329,26230,55160,113622,10497,219790,4233,25924,9771,10125,5159,11138,120892,57580,8822,125058,26297,2260,26084,8660,5903,5924,57480,153,3082,57531,160518,10160,9515,9826,57144,23216,29091,9853,3843,2059,5585,9912,26056,23263,57522,128239,23158,4684,8531,79958,114793,2674,9699,2264,5058,10451,54453,64283,54885,9693,23101,11069,221178,84033,55357,85440,29941,23677,2906,9882 EXPH5,DMXL2,BTC,DOCK1,DENND3,DOCK2,TBC1D30,TIAM2,ARHGEF10L,ADPRHL1,UNC13B,RTKN2,MET,MYRIP,RAPGEF5,RASGRP1,PDGFRB,TBC1D8,LRRK2,PREX1,FGF17,TBC1D16,SERGEF,FGFR1,ARHGEF26,IRS2,RANBP2,RASGRF2,PLEKHG1,ADRB1,HGF,HACE1,DENND5B,FARP1,STXBP5L,ARHGEF11,PAK5,TBC1D1,STXBP6,RUSC2,IPO5,EPS8,PKN1,ARHGAP44,RAB11FIP5,MCF2L,SRGAP1,IQGAP3,TBC1D9,NCAM1,YBX3,DENND1C,FMNL2,GFRA1,RIMS2,FGFR4,PAK1,VAV3,RIN2,ARHGEF28,TBC1D8B,RAPGEF2,MCF2L2,RAPGEF4,SPATA13,OBSCN,TBC1D2,DOCK7,PKN3,SH3BP4,GRIN2D,TBC1D4 GO:0000976 transcription regulatory region sequence-specific DNA binding 0.00138490199969491 -6.58212590018935 738 97 0.0577380952380952 1680 17224 64764,29842,5071,9658,5013,2625,6777,255877,1050,7227,64376,8320,29841,604,5452,2115,2023,2735,7080,30818,468,4212,2649,11166,579,4774,4779,10413,100271849,467,23314,474,10538,53335,55509,4088,9242,81931,22806,3131,60468,619279,54937,148523,688,1628,1746,63973,3219,29942,4208,64919,11279,860,4601,55893,23051,5966,122953,5324,51222,6304,4825,93986,2624,168620,4609,6720,7020,8531,4091,148979,56033,1052,30062,4487,3174,2104,3164,84159,100289635,9516,9935,639,7545,1051,64324,5325,138151,26508,7494,3239,5083,26257,64754,10736,1649 CREB3L2,TFCP2L1,PRKN,ZNF516,OTX1,GATA3,STAT5B,BCL6B,CEBPA,TRPS1,IKZF5,EOMES,GRHL1,BCL6,POU2F2,ETV1,ENO1,GLI1,NKX2-1,KCNIP3,ATF4,MEIS2,NR6A1,SOX21,NKX3-2,NFIA,NFE2L1,YAP1,MEF2B,ATF3,SATB2,ATOH1,BATF,BCL11A,BATF3,SMAD3,MSC,ZNF93,IKZF3,HLF,BACH2,ZNF704,SOHLH2,CIART,KLF5,DBP,DLX2,NEUROG2,HOXB9,PURG,MEF2C,BCL11B,KLF8,RUNX2,MXI1,ZNF395,ZHX3,REL,JDP2,PLAG1,ZNF219,SATB1,NKX6-1,FOXP2,GATA2,BHLHA15,MYC,SREBF1,TFAP2A,YBX3,SMAD6,GLIS1,BARX1,CEBPD,RAX,MSX1,HNF4G,ESRRG,NR4A1,ARID5B,ZNF605,LITAF,MAFB,PRDM1,ZIC1,CEBPB,NSD1,PLAGL1,NACC2,HEYL,XBP1,HOXD13,PAX9,NKX2-8,SMYD3,SIX2,DDIT3 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding 0.00140307495316959 -6.56908905578945 417 60 0.0357142857142857 1680 17224 64764,64919,860,5324,5966,5013,2625,6777,1050,58495,7227,29841,2624,4609,168620,6720,57593,7020,5452,2115,148979,56033,1052,30062,468,4212,4487,3174,2649,11166,2104,3164,4774,9516,4779,9935,100271849,467,23314,474,10538,3198,7545,1879,1051,22806,3131,5325,26508,54937,688,3239,1746,1628,5083,26257,10736,1649,3169,4208 CREB3L2,BCL11B,RUNX2,PLAG1,REL,OTX1,GATA3,STAT5B,CEBPA,OVOL2,TRPS1,GRHL1,GATA2,MYC,BHLHA15,SREBF1,EBF4,TFAP2A,POU2F2,ETV1,GLIS1,BARX1,CEBPD,RAX,ATF4,MEIS2,MSX1,HNF4G,NR6A1,SOX21,ESRRG,NR4A1,NFIA,LITAF,NFE2L1,MAFB,MEF2B,ATF3,SATB2,ATOH1,BATF,HOXA1,ZIC1,EBF1,CEBPB,IKZF3,HLF,PLAGL1,HEYL,SOHLH2,KLF5,HOXD13,DLX2,DBP,PAX9,NKX2-8,SIX2,DDIT3,FOXA1,MEF2C GO:0043548 phosphatidylinositol 3-kinase binding 0.00141925371233123 -6.55762410021756 24 8 0.00476190476190476 1680 17224 7301,8660,153090,25827,3480,118788,5783,23551 TYRO3,IRS2,DAB2IP,FBXL2,IGF1R,PIK3AP1,PTPN13,RASD2 GO:0042578 phosphoric ester hydrolase activity 0.00143504691393084 -6.54655773767021 367 54 0.0321428571428571 1680 17224 3636,5153,1850,5789,84959,11099,147111,64900,81544,3628,80055,2070,22843,8611,8555,10846,27143,9896,5144,5521,5791,10924,1131,1843,5210,5509,54961,10076,5208,5783,5777,284161,9829,8612,1852,5151,64077,92370,23236,64943,27293,2822,5788,5167,5795,64748,133121,8821,142679,5802,5799,22876,5337,5723 INPPL1,PDE1B,DUSP8,PTPRD,UBASH3B,PTPN21,NOTUM,LPIN3,GDPD5,INPP1,PGAP1,EYA4,PPM1E,PLPP1,CDC14B,PDE10A,PALD1,FIG4,PDE4D,PPP2R2B,PTPRE,SMPDL3A,CHRM3,DUSP1,PFKFB4,PPP1R3D,SSH3,PTPRU,PFKFB2,PTPN13,PTPN6,GDPD1,DNAJC6,PLPP2,DUSP9,PDE8A,LHPP,PXYLP1,PLCB1,NT5DC2,SMPDL3B,GPLD1,PTPRC,ENPP1,PTPRJ,PLPPR2,ENPP6,INPP4B,DUSP19,PTPRS,PTPRN2,INPP5F,PLD1,PSPH GO:0015318 inorganic molecular entity transmembrane transporter activity 0.00144177006244402 -6.54188371022378 855 110 0.0654761904761905 1680 17224 10368,2898,10396,55283,3709,114134,6542,785,10560,84679,23413,7881,1138,3781,51310,6567,5002,347735,3790,7220,54805,154091,140738,6326,27112,92270,6328,9312,2823,30818,6520,10257,23507,285335,64116,27133,475,56704,8973,81894,1244,3752,481,10052,6541,23516,27345,540,3755,41,150159,160518,27012,55129,57156,256987,6331,6536,2561,6334,90423,2566,120103,2621,2570,6507,9990,3749,90550,255231,3761,219527,7782,23657,6324,783,27094,220963,55117,79815,728215,85414,490,54795,56901,30061,54020,3786,11001,206358,777,2894,6262,94015,22821,60598,55002,2900,84879,11182,8140,2906,6510,7222,117247,781,493,9619,478,8501 CACNG3,GRIK2,ATP8A1,MCOLN3,ITPR2,SLC2A13,SLC7A2,CACNB4,SLC19A2,SLC9A7,NCS1,KCNAB1,CHRNA5,KCNN2,SLC22A17,SLC16A2,SLC22A18,SERINC2,KCNS3,TRPC1,CNNM2,SLC2A12,TMEM37,SCN2A,FAM155B,ATP6AP1L,SCN3A,KCNB2,GPM6A,KCNIP3,SLC3A2,ABCC4,LRRC8B,SLC9C1,SLC39A8,KCNH5,ATOX1,JPH1,CHRNA6,SLC25A28,ABCC2,KCND3,ATP1B1,GJC1,SLC7A1,SLC39A14,KCNMB4,ATP7B,KCNG1,ASIC1,SLC9B1,DENND5B,KCNV1,ANO10,TMEM63C,SERINC5,SCN5A,SLC6A9,GABRB2,SCN8A,ATP6V1E2,GABRG2,SLC36A4,GAS6,GABRR2,SLC1A3,SLC12A6,KCNC4,MCU,MCOLN2,KCNJ4,LRRC55,SLC30A4,SLC7A11,SCN1B,CACNB2,KCNMB3,SLC16A9,SLC6A15,NIPAL2,FAM155A,SLC45A3,ATP2B1,TRPM4,NDUFA4L2,SLC40A1,SLC37A1,KCNQ3,SLC27A2,SLC36A1,CACNA1E,GRID1,RYR2,TTYH2,RASA3,KCNK15,TMCO3,GRIK4,MFSD2A,SLC2A6,SLC7A5,GRIN2D,SLC1A5,TRPC3,SLC16A10,CACNA2D1,ATP2B4,ABCG1,ATP1A3,SLC43A1 GO:0005522 profilin binding 0.00145322392441715 -6.53397079448744 10 5 0.00297619047619048 1680 17224 1627,23433,2017,51466,27445 DBN1,RHOQ,CTTN,EVL,PCLO GO:0016829 lyase activity 0.00149315026196264 -6.50686712117415 182 31 0.018452380952381 1680 17224 1962,241,2026,7390,171425,4259,4597,107,9200,48,2194,875,79094,2977,23483,767,64850,377677,201161,760,200558,230,226,5066,112,85007,5106,87769,2023,1491,2731 EHHADH,ALOX5AP,ENO2,UROS,CLYBL,MGST3,MVD,ADCY1,HACD1,ACO1,FASN,CBS,CHAC1,GUCY1A2,TGDS,CA8,ETNPPL,CA13,CENPV,CA2,APLF,ALDOC,ALDOA,PAM,ADCY6,PHYKPL,PCK2,GGACT,ENO1,CTH,GLDC GO:0031267 small GTPase binding 0.00149786570803956 -6.50371404540932 564 77 0.0458333333333333 1680 17224 23086,23312,685,1793,22898,1794,23329,26230,55160,113622,10497,219790,4233,25924,9771,10125,5159,11138,120892,57580,8822,125058,26297,2260,26084,8660,5903,5924,57480,153,3082,57531,160518,10160,9515,9826,57144,23216,29091,9853,3843,2059,5585,9912,26056,23263,57522,128239,23158,4684,8531,79958,114793,2674,9699,220441,2264,5058,10451,54453,64283,116984,54885,9693,23101,11069,55616,221178,84033,116986,51555,55357,85440,29941,23677,2906,9882 EXPH5,DMXL2,BTC,DOCK1,DENND3,DOCK2,TBC1D30,TIAM2,ARHGEF10L,ADPRHL1,UNC13B,RTKN2,MET,MYRIP,RAPGEF5,RASGRP1,PDGFRB,TBC1D8,LRRK2,PREX1,FGF17,TBC1D16,SERGEF,FGFR1,ARHGEF26,IRS2,RANBP2,RASGRF2,PLEKHG1,ADRB1,HGF,HACE1,DENND5B,FARP1,STXBP5L,ARHGEF11,PAK5,TBC1D1,STXBP6,RUSC2,IPO5,EPS8,PKN1,ARHGAP44,RAB11FIP5,MCF2L,SRGAP1,IQGAP3,TBC1D9,NCAM1,YBX3,DENND1C,FMNL2,GFRA1,RIMS2,RNF152,FGFR4,PAK1,VAV3,RIN2,ARHGEF28,ARAP2,TBC1D8B,RAPGEF2,MCF2L2,RAPGEF4,ASAP3,SPATA13,OBSCN,AGAP2,PEX5L,TBC1D2,DOCK7,PKN3,SH3BP4,GRIN2D,TBC1D4 GO:0001540 amyloid-beta binding 0.00156925855483316 -6.45715202923894 60 14 0.00833333333333333 1680 17224 590,25825,8322,84570,23621,3949,322,3673,4481,10859,320,321,478,54103 BCHE,BACE2,FZD4,COL25A1,BACE1,LDLR,APBB1,ITGA2,MSR1,LILRB1,APBA1,APBA2,ATP1A3,GSAP GO:0015459 potassium channel regulator activity 0.00177540856920763 -6.33372470270679 48 12 0.00714285714285714 1680 17224 57628,27012,219527,30818,27345,7881,27094,3790,23678,6446,57463,10110 DPP10,KCNV1,LRRC55,KCNIP3,KCNMB4,KCNAB1,KCNMB3,KCNS3,SGK3,SGK1,AMIGO1,SGK2 GO:0017080 sodium channel regulator activity 0.00180063476066274 -6.31961603143195 36 10 0.00595238095238095 1680 17224 2258,6324,23678,2257,6446,5318,10110,4734,493,2822 FGF13,SCN1B,SGK3,FGF12,SGK1,PKP2,SGK2,NEDD4,ATP2B4,GPLD1 GO:0004725 protein tyrosine phosphatase activity 0.00182524725039412 -6.30603982145621 102 20 0.0119047619047619 1680 17224 54961,1850,10076,5789,5777,5783,84959,11099,9829,1852,2070,5788,5795,8555,27143,142679,5802,5799,5791,1843 SSH3,DUSP8,PTPRU,PTPRD,PTPN6,PTPN13,UBASH3B,PTPN21,DNAJC6,DUSP9,EYA4,PTPRC,PTPRJ,CDC14B,PALD1,DUSP19,PTPRS,PTPRN2,PTPRE,DUSP1 GO:0031434 mitogen-activated protein kinase kinase binding 0.00197953614848698 -6.22489273016175 68 15 0.00892857142857143 1680 17224 2042,7301,2264,57761,3480,84451,4916,153090,4919,2051,4233,2047,780,2260,5159 EPHA3,TYRO3,FGFR4,TRIB3,IGF1R,MAP3K21,NTRK3,DAB2IP,ROR1,EPHB6,MET,EPHB1,DDR1,FGFR1,PDGFRB GO:0004312 fatty acid synthase activity 0.00245103605873572 -6.0112444626979 11 5 0.00297619047619048 1680 17224 6785,79993,55301,83401,2194 ELOVL4,ELOVL7,OLAH,ELOVL3,FASN GO:0005216 ion channel activity 0.00245755626694944 -6.00858781019308 427 60 0.0357142857142857 1680 17224 27012,55129,6331,57156,10368,2898,2561,6334,55283,2566,3709,2621,2570,3749,785,23413,90550,255231,219527,3761,7881,1138,3781,6324,783,27094,3790,7220,140738,6326,27112,728215,9312,6328,54795,30061,2823,30818,3786,285335,23507,27133,777,56704,2894,6262,8973,94015,22821,3752,10052,2900,60598,27345,3755,41,2906,7222,781,160518 KCNV1,ANO10,SCN5A,TMEM63C,CACNG3,GRIK2,GABRB2,SCN8A,MCOLN3,GABRG2,ITPR2,GAS6,GABRR2,KCNC4,CACNB4,NCS1,MCU,MCOLN2,LRRC55,KCNJ4,KCNAB1,CHRNA5,KCNN2,SCN1B,CACNB2,KCNMB3,KCNS3,TRPC1,TMEM37,SCN2A,FAM155B,FAM155A,KCNB2,SCN3A,TRPM4,SLC40A1,GPM6A,KCNIP3,KCNQ3,SLC9C1,LRRC8B,KCNH5,CACNA1E,JPH1,GRID1,RYR2,CHRNA6,TTYH2,RASA3,KCND3,GJC1,GRIK4,KCNK15,KCNMB4,KCNG1,ASIC1,GRIN2D,TRPC3,CACNA2D1,DENND5B GO:0019198 transmembrane receptor protein phosphatase activity 0.00288807606682043 -5.84716471937168 16 6 0.00357142857142857 1680 17224 5799,5788,10076,5791,5789,5777 PTPRN2,PTPRC,PTPRU,PTPRE,PTPRD,PTPN6 GO:0004697 protein kinase C activity 0.00288807606682043 -5.84716471937168 16 6 0.00357142857142857 1680 17224 5588,5578,5585,5579,29941,5580 PRKCQ,PRKCA,PKN1,PRKCB,PKN3,PRKCD GO:0005001 transmembrane receptor protein tyrosine phosphatase activity 0.00288807606682043 -5.84716471937168 16 6 0.00357142857142857 1680 17224 5799,5788,10076,5791,5789,5777 PTPRN2,PTPRC,PTPRU,PTPRE,PTPRD,PTPN6 GO:1990837 sequence-specific double-stranded DNA binding 0.00291559005597521 -5.83768305908928 774 99 0.0589285714285714 1680 17224 64764,29842,5071,9658,5013,2625,6777,255877,1050,7227,64376,8320,29841,604,5452,2115,2023,2735,7080,30818,468,4212,2649,11166,579,4774,4779,10413,100271849,467,23314,474,10538,53335,55509,4088,9242,81931,22806,3131,60468,619279,54937,148523,688,1628,1746,63973,3219,29942,4208,23462,64919,11279,860,4601,55893,23051,5966,122953,5324,51222,6304,4825,93986,2624,168620,4609,6720,7020,8531,4091,148979,56033,1052,30062,4487,10765,3174,2104,3164,84159,100289635,9516,9935,639,7545,1051,64324,5325,138151,26508,7494,3239,5083,26257,64754,10736,1649 CREB3L2,TFCP2L1,PRKN,ZNF516,OTX1,GATA3,STAT5B,BCL6B,CEBPA,TRPS1,IKZF5,EOMES,GRHL1,BCL6,POU2F2,ETV1,ENO1,GLI1,NKX2-1,KCNIP3,ATF4,MEIS2,NR6A1,SOX21,NKX3-2,NFIA,NFE2L1,YAP1,MEF2B,ATF3,SATB2,ATOH1,BATF,BCL11A,BATF3,SMAD3,MSC,ZNF93,IKZF3,HLF,BACH2,ZNF704,SOHLH2,CIART,KLF5,DBP,DLX2,NEUROG2,HOXB9,PURG,MEF2C,HEY1,BCL11B,KLF8,RUNX2,MXI1,ZNF395,ZHX3,REL,JDP2,PLAG1,ZNF219,SATB1,NKX6-1,FOXP2,GATA2,BHLHA15,MYC,SREBF1,TFAP2A,YBX3,SMAD6,GLIS1,BARX1,CEBPD,RAX,MSX1,KDM5B,HNF4G,ESRRG,NR4A1,ARID5B,ZNF605,LITAF,MAFB,PRDM1,ZIC1,CEBPB,NSD1,PLAGL1,NACC2,HEYL,XBP1,HOXD13,PAX9,NKX2-8,SMYD3,SIX2,DDIT3 GO:0030165 PDZ domain binding 0.00313351960814353 -5.76559843073382 78 16 0.00952380952380952 1680 17224 5071,55970,2898,51232,8322,8325,9693,59338,10458,3761,7049,153,92,490,493,8321 PRKN,GNG12,GRIK2,CRIM1,FZD4,FZD8,RAPGEF2,PLEKHA1,BAIAP2,KCNJ4,TGFBR3,ADRB1,ACVR2A,ATP2B1,ATP2B4,FZD1 GO:0022857 transmembrane transporter activity 0.00330350843673185 -5.71277021262084 1069 131 0.0779761904761905 1680 17224 10368,54847,55640,2898,10396,55283,3709,114134,785,28232,84679,23413,7881,3781,6567,5002,84068,3790,347735,7220,54805,154091,140738,2823,30818,6520,10257,285335,475,56704,81894,1244,3752,94081,6541,27345,540,148808,150159,27012,9899,6331,57156,2561,6334,9481,90423,120103,6507,255231,7782,23657,23461,783,4040,220963,79815,353189,728215,56901,54020,3786,206358,11001,6262,94015,26872,60598,55002,2900,84879,11182,1015,7222,6542,10560,51310,1138,27112,6326,92270,9312,6328,23507,27133,119559,64116,8973,481,10052,23516,41,3755,84976,160518,55129,256987,6536,2566,9990,2570,2621,81855,80723,3749,90550,222553,219527,3761,6324,27094,55117,85414,490,54795,30061,777,2894,22821,8140,81796,116843,2906,55356,6510,781,493,117247,478,8501,9619 CACNG3,SIDT1,FLVCR2,GRIK2,ATP8A1,MCOLN3,ITPR2,SLC2A13,CACNB4,SLCO3A1,SLC9A7,NCS1,KCNAB1,KCNN2,SLC16A2,SLC22A18,SLC10A7,KCNS3,SERINC2,TRPC1,CNNM2,SLC2A12,TMEM37,GPM6A,KCNIP3,SLC3A2,ABCC4,SLC9C1,ATOX1,JPH1,SLC25A28,ABCC2,KCND3,SFXN1,SLC7A1,KCNMB4,ATP7B,MFSD4A,SLC9B1,KCNV1,SV2B,SCN5A,TMEM63C,GABRB2,SCN8A,SLC25A27,ATP6V1E2,SLC36A4,SLC1A3,MCOLN2,SLC30A4,SLC7A11,ABCA5,CACNB2,LRP6,SLC16A9,NIPAL2,SLCO4C1,FAM155A,NDUFA4L2,SLC37A1,KCNQ3,SLC36A1,SLC27A2,RYR2,TTYH2,STEAP1,KCNK15,TMCO3,GRIK4,MFSD2A,SLC2A6,CDH17,TRPC3,SLC7A2,SLC19A2,SLC22A17,CHRNA5,FAM155B,SCN2A,ATP6AP1L,KCNB2,SCN3A,LRRC8B,KCNH5,SFXN4,SLC39A8,CHRNA6,ATP1B1,GJC1,SLC39A14,ASIC1,KCNG1,DISP1,DENND5B,ANO10,SERINC5,SLC6A9,GABRG2,SLC12A6,GABRR2,GAS6,SFXN3,SLC35G2,KCNC4,MCU,SLC35F1,LRRC55,KCNJ4,SCN1B,KCNMB3,SLC6A15,SLC45A3,ATP2B1,TRPM4,SLC40A1,CACNA1E,GRID1,RASA3,SLC7A5,SLCO5A1,SLC18B1,GRIN2D,SLC22A15,SLC1A5,CACNA2D1,ATP2B4,SLC16A10,ATP1A3,SLC43A1,ABCG1 GO:0019901 protein kinase binding 0.00356373276509211 -5.63694675392107 618 81 0.0482142857142857 1680 17224 2042,5071,29984,5611,5318,119,4869,4916,5596,1488,780,5881,6497,8153,9465,51339,26960,153090,4082,2051,4233,3556,5159,9846,468,5208,287,5777,5577,481,4919,1832,2260,7453,4088,55450,8660,10718,5795,51704,5579,84451,142679,148252,8829,143384,84978,7301,6331,55857,2888,9886,4038,2621,5585,2047,3480,1938,5580,2690,6720,59,112,54206,10253,6850,2264,23433,6262,10399,8631,9261,5788,57761,2268,390,257144,5608,1000,2810,5569 EPHA3,PRKN,RHOD,DNAJC3,PKP2,ADD2,NPM1,NTRK3,MAPK4,CTBP2,DDR1,RAC3,SKI,RND2,AKAP7,DACT1,NBEA,DAB2IP,MARCKS,EPHB6,MET,IL1RAP,PDGFRB,GAB2,ATF4,PFKFB2,ANK2,PTPN6,PRKAR2B,ATP1B1,ROR1,DSP,FGFR1,WARS,SMAD3,CAMK2N1,IRS2,NRG3,PTPRJ,GPRC5B,PRKCB,MAP3K21,DUSP19,DIRAS1,NRP1,CACUL1,FRMD5,TYRO3,SCN5A,KIZ,GRB14,RHOBTB1,LRP4,GAS6,PKN1,EPHB1,IGF1R,EEF2,PRKCD,GHR,SREBF1,ACTA2,ADCY6,ERRFI1,SPRY2,SYK,FGFR4,RHOQ,RYR2,RACK1,SKAP1,MAPKAPK2,PTPRC,TRIB3,FGR,RND3,GCSAM,MAP2K6,CDH2,SFN,PKIA GO:0000166 nucleotide binding 0.00388787746627301 -5.54989190875686 2092 239 0.142261904761905 1680 17224 349565,4598,2180,90,3798,10396,7358,51175,445,1488,5578,5881,16,8428,10382,5891,8153,9531,6196,7881,9465,1768,5911,25837,54805,2051,5567,5159,51062,10188,4139,10257,130399,120892,5577,1244,93,4919,10110,157,2770,9149,203,5167,10769,10827,540,2081,56898,5603,148252,5287,144132,58528,51084,5563,833,7301,26524,860,9886,11149,6334,9748,1718,284716,65997,29899,26227,122622,26038,134266,116835,253461,56952,1938,3480,57143,23461,200558,10846,5592,222537,112,80216,55137,375449,4846,3156,5058,2264,23433,4651,11001,11069,2194,55437,84033,8476,197257,55760,9261,57494,29941,11031,3099,6713,1717,162394,79646,387751,6296,92170,2042,26052,152110,29984,4430,1147,5596,4916,2870,23046,780,91351,114112,10290,440,8564,83694,140469,92,22989,2272,5144,5874,4233,379,1767,3306,2241,91807,2597,2617,7846,5163,5208,4597,51700,53354,107,5588,481,23682,79739,2444,57205,260425,2260,7453,27010,953,64208,5579,2633,5754,84451,3248,657,5413,5602,27314,22983,23043,4642,8444,659,57144,10079,54622,338323,402,3800,51655,5028,5585,2047,5580,30845,23551,2963,23678,59,6446,5593,79659,5106,4646,55964,22800,6850,2242,490,83666,5210,54795,9645,26873,5865,217,51560,9693,389643,81788,205,4141,116986,23250,2977,79834,57761,2268,390,2329,5608,2775,10000,79858,138429,55605,3098,79705,2669,129607,23095,51776,493,9619,478 NMNAT3,MVK,ACSL1,ACVR1,KIF5A,ATP8A1,UGDH,TUBE1,ASS1,CTBP2,PRKCA,RAC3,AARS,STK24,TUBB4A,MOK,RND2,BAG3,RPS6KA2,KCNAB1,AKAP7,DNAH6,RAP2A,RAB26,CNNM2,EPHB6,PRKACB,PDGFRB,ATL1,TNK2,MARK1,ABCC4,ACVR1C,LRRK2,PRKAR2B,ABCC2,ACVR2B,ROR1,SGK2,GRK3,GNAI1,DYRK1B,AK1,ENPP1,PLK2,FAM114A2,ATP7B,ERN1,BDH2,MAPK13,DIRAS1,PIK3C2B,DNHD1,RRAGD,CRYL1,PRKAA2,CARS,TYRO3,LATS2,RUNX2,RHOBTB1,BVES,SCN8A,SLK,DHCR24,RIMKLA,RASL11B,GPSM2,PHGDH,ADSSL1,CHD5,GRPEL2,HSPA12B,ZBTB38,PRTFDC1,EEF2,IGF1R,ADCK1,ABCA5,APLF,PDE10A,PRKG1,HS3ST5,ADCY6,ALPK1,FIGN,MAST4,NOS3,HMGCR,PAK1,FGFR4,RHOQ,MYO10,SLC27A2,RAPGEF4,FASN,STRADB,OBSCN,CDC42BPA,LDHD,DHX32,MAPKAPK2,RIMKLB,PKN3,RAB31,HK2,SQLE,DHCR7,SLFN5,PANK3,GVINP1,ACSM3,MTG1,EPHA3,DNM3,NEK10,RHOD,MYO1B,CHUK,MAPK4,NTRK3,GRK6,KIF21B,DDR1,DDX60L,TXNRD3,SPEG,ASNS,KMO,RPS6KL1,MYO3B,ACVR2A,MYH15,FHIT,PDE4D,RAB27B,MET,ARL4D,DNAH5,HSPA2,FER,MYLK3,GAPDH,GARS,TUBA1A,PDK1,PFKFB2,MVD,CYB5R2,PANK1,ADCY1,PRKCQ,ATP1B1,RAB38,TTLL7,FRK,ATP10D,MAGI3,FGFR1,WARS,TPK1,ENTPD1,POPDC3,PRKCB,GBP1,PTK7,MAP3K21,HPGD,BMPR1A,SEPT5,MAPK10,RAB30,MAST1,TNIK,MYO1D,DYRK3,BMPR2,PAK5,ATP9A,ARL15,NLRP14,ARL2,KIF5C,RASD1,P2RY1,PKN1,EPHB1,PRKCD,EHD3,RASD2,GTF2F2,SGK3,ACTA2,SGK1,PRKG2,DYNC2H1,PCK2,MYO6,SEPT3,RRAS2,SYK,FES,ATP2B1,PARP9,PFKFB4,TRPM4,MICAL2,OPLAH,RAB3B,ALDH2,RAB6B,RAPGEF2,NUGGC,NUAK2,AK4,MARS,AGAP2,ATP11A,GUCY1A2,PEAK1,TRIB3,FGR,RND3,FMO4,MAP2K6,GNAO1,AKT3,NEK11,PIP5KL1,KIF21A,HK1,LRRK1,GEM,CMPK2,KIF1B,MAP3K20,ATP2B4,ABCG1,ATP1A3 GO:1901265 nucleoside phosphate binding 0.00397994878691207 -5.52648632737861 2093 239 0.142261904761905 1680 17224 349565,4598,2180,90,3798,10396,7358,51175,445,1488,5578,5881,16,8428,10382,5891,8153,9531,6196,7881,9465,1768,5911,25837,54805,2051,5567,5159,51062,10188,4139,10257,130399,120892,5577,1244,93,4919,10110,157,2770,9149,203,5167,10769,10827,540,2081,56898,5603,148252,5287,144132,58528,51084,5563,833,7301,26524,860,9886,11149,6334,9748,1718,284716,65997,29899,26227,122622,26038,134266,116835,253461,56952,1938,3480,57143,23461,200558,10846,5592,222537,112,80216,55137,375449,4846,3156,5058,2264,23433,4651,11001,11069,2194,55437,84033,8476,197257,55760,9261,57494,29941,11031,3099,6713,1717,162394,79646,387751,6296,92170,2042,26052,152110,29984,4430,1147,5596,4916,2870,23046,780,91351,114112,10290,440,8564,83694,140469,92,22989,2272,5144,5874,4233,379,1767,3306,2241,91807,2597,2617,7846,5163,5208,4597,51700,53354,107,5588,481,23682,79739,2444,57205,260425,2260,7453,27010,953,64208,5579,2633,5754,84451,3248,657,5413,5602,27314,22983,23043,4642,8444,659,57144,10079,54622,338323,402,3800,51655,5028,5585,2047,5580,30845,23551,2963,23678,59,6446,5593,79659,5106,4646,55964,22800,6850,2242,490,83666,5210,54795,9645,26873,5865,217,51560,9693,389643,81788,205,4141,116986,23250,2977,79834,57761,2268,390,2329,5608,2775,10000,79858,138429,55605,3098,79705,2669,129607,23095,51776,493,9619,478 NMNAT3,MVK,ACSL1,ACVR1,KIF5A,ATP8A1,UGDH,TUBE1,ASS1,CTBP2,PRKCA,RAC3,AARS,STK24,TUBB4A,MOK,RND2,BAG3,RPS6KA2,KCNAB1,AKAP7,DNAH6,RAP2A,RAB26,CNNM2,EPHB6,PRKACB,PDGFRB,ATL1,TNK2,MARK1,ABCC4,ACVR1C,LRRK2,PRKAR2B,ABCC2,ACVR2B,ROR1,SGK2,GRK3,GNAI1,DYRK1B,AK1,ENPP1,PLK2,FAM114A2,ATP7B,ERN1,BDH2,MAPK13,DIRAS1,PIK3C2B,DNHD1,RRAGD,CRYL1,PRKAA2,CARS,TYRO3,LATS2,RUNX2,RHOBTB1,BVES,SCN8A,SLK,DHCR24,RIMKLA,RASL11B,GPSM2,PHGDH,ADSSL1,CHD5,GRPEL2,HSPA12B,ZBTB38,PRTFDC1,EEF2,IGF1R,ADCK1,ABCA5,APLF,PDE10A,PRKG1,HS3ST5,ADCY6,ALPK1,FIGN,MAST4,NOS3,HMGCR,PAK1,FGFR4,RHOQ,MYO10,SLC27A2,RAPGEF4,FASN,STRADB,OBSCN,CDC42BPA,LDHD,DHX32,MAPKAPK2,RIMKLB,PKN3,RAB31,HK2,SQLE,DHCR7,SLFN5,PANK3,GVINP1,ACSM3,MTG1,EPHA3,DNM3,NEK10,RHOD,MYO1B,CHUK,MAPK4,NTRK3,GRK6,KIF21B,DDR1,DDX60L,TXNRD3,SPEG,ASNS,KMO,RPS6KL1,MYO3B,ACVR2A,MYH15,FHIT,PDE4D,RAB27B,MET,ARL4D,DNAH5,HSPA2,FER,MYLK3,GAPDH,GARS,TUBA1A,PDK1,PFKFB2,MVD,CYB5R2,PANK1,ADCY1,PRKCQ,ATP1B1,RAB38,TTLL7,FRK,ATP10D,MAGI3,FGFR1,WARS,TPK1,ENTPD1,POPDC3,PRKCB,GBP1,PTK7,MAP3K21,HPGD,BMPR1A,SEPT5,MAPK10,RAB30,MAST1,TNIK,MYO1D,DYRK3,BMPR2,PAK5,ATP9A,ARL15,NLRP14,ARL2,KIF5C,RASD1,P2RY1,PKN1,EPHB1,PRKCD,EHD3,RASD2,GTF2F2,SGK3,ACTA2,SGK1,PRKG2,DYNC2H1,PCK2,MYO6,SEPT3,RRAS2,SYK,FES,ATP2B1,PARP9,PFKFB4,TRPM4,MICAL2,OPLAH,RAB3B,ALDH2,RAB6B,RAPGEF2,NUGGC,NUAK2,AK4,MARS,AGAP2,ATP11A,GUCY1A2,PEAK1,TRIB3,FGR,RND3,FMO4,MAP2K6,GNAO1,AKT3,NEK11,PIP5KL1,KIF21A,HK1,LRRK1,GEM,CMPK2,KIF1B,MAP3K20,ATP2B4,ABCG1,ATP1A3 GO:0030676 Rac guanyl-nucleotide exchange factor activity 0.00409884722790285 -5.497049508732 17 6 0.00357142857142857 1680 17224 10451,10160,1794,2059,57580,221178 VAV3,FARP1,DOCK2,EPS8,PREX1,SPATA13 GO:1901981 phosphatidylinositol phosphate binding 0.00415123312731103 -5.48434984976552 147 25 0.0148809523809524 1680 17224 116984,4139,4651,84725,29091,54477,9265,4430,10979,3092,59338,23236,5217,1687,85477,25851,115548,57732,114879,55353,153090,285590,79958,134829,9846 ARAP2,MARK1,MYO10,PLEKHA8,STXBP6,PLEKHA5,CYTH3,MYO1B,FERMT2,HIP1,PLEKHA1,PLCB1,PFN2,GSDME,SCIN,TECPR1,FCHO2,ZFYVE28,OSBPL5,LAPTM4B,DAB2IP,SH3PXD2B,DENND1C,CLVS2,GAB2 GO:0005088 Ras guanyl-nucleotide exchange factor activity 0.00418208731960531 -5.47694479832631 251 38 0.0226190476190476 1680 17224 685,10160,9826,1793,2059,22898,1794,26230,55160,23263,79958,4233,4684,2674,9771,10125,5159,2264,10451,54453,64283,9693,23101,11069,221178,57580,84033,8822,26297,2260,26084,8660,5924,57480,153,2906,3082,160518 BTC,FARP1,ARHGEF11,DOCK1,EPS8,DENND3,DOCK2,TIAM2,ARHGEF10L,MCF2L,DENND1C,MET,NCAM1,GFRA1,RAPGEF5,RASGRP1,PDGFRB,FGFR4,VAV3,RIN2,ARHGEF28,RAPGEF2,MCF2L2,RAPGEF4,SPATA13,PREX1,OBSCN,FGF17,SERGEF,FGFR1,ARHGEF26,IRS2,RASGRF2,PLEKHG1,ADRB1,GRIN2D,HGF,DENND5B GO:0016836 hydro-lyase activity 0.00431041428191655 -5.44672125839149 53 12 0.00714285714285714 1680 17224 760,1962,2026,7390,9200,48,2194,875,23483,767,2023,377677 CA2,EHHADH,ENO2,UROS,HACD1,ACO1,FASN,CBS,TGDS,CA8,ENO1,CA13 GO:0097110 scaffold protein binding 0.00431041428191655 -5.44672125839149 53 12 0.00714285714285714 1680 17224 6331,9495,4038,57502,7431,1147,3709,5144,5028,1832,493,4846 SCN5A,AKAP5,LRP4,NLGN4X,VIM,CHUK,ITPR2,PDE4D,P2RY1,DSP,ATP2B4,NOS3 GO:0008194 UDP-glycosyltransferase activity 0.00454412920409784 -5.39391916396712 148 25 0.0148809523809524 1680 17224 337876,90693,727936,7368,2651,8708,79695,11226,64131,11282,23127,114805,64409,22856,146664,283358,79623,2591,2589,26301,4245,8707,374378,11285,9331 CHSY3,CCDC126,GXYLT2,UGT8,GCNT2,B3GALT1,GALNT12,GALNT6,XYLT1,MGAT4B,COLGALT2,GALNT13,GALNT17,CHSY1,MGAT5B,B4GALNT3,GALNT14,GALNT3,GALNT1,GBGT1,MGAT1,B3GALT2,GALNT18,B4GALT7,B4GALT6 GO:0071936 coreceptor activity involved in Wnt signaling pathway 0.0045745959473564 -5.3872369016726 8 4 0.00238095238095238 1680 17224 4040,4919,5754,10082 LRP6,ROR1,PTK7,GPC6 GO:0050839 cell adhesion molecule binding 0.00468093862745212 -5.36425662774094 483 65 0.0386904761904762 1680 17224 57530,4430,5318,22837,253559,9378,5578,85456,51429,1496,8428,4072,9531,8496,3690,22859,153090,2017,1363,2023,1627,3695,90102,6520,1285,23670,8838,26136,5777,57502,1832,83700,2995,3673,226,84978,10178,2335,5789,9748,29091,3655,6402,7082,6164,1938,1829,4646,114793,6850,60437,2194,10399,10458,55357,143098,2200,7060,1015,54874,1000,2810,23367,57698,23348 CGN,MYO1B,PKP2,COBLL1,CADM2,NRXN1,PRKCA,TNKS1BP1,SNX9,CTNNA2,STK24,EPCAM,BAG3,PPFIBP1,ITGB3,ADGRL1,DAB2IP,CTTN,CPE,ENO1,DBN1,ITGB7,PHLDB2,SLC3A2,COL4A3,CEMIP2,WISP3,TES,PTPN6,NLGN4X,DSP,JAM3,GYPC,ITGA2,ALDOA,FRMD5,TENM1,FN1,PTPRD,SLK,STXBP6,ITGA6,SELL,TJP1,RPL34,EEF2,DSG2,MYO6,FMNL2,SYK,CDH26,FASN,RACK1,BAIAP2,TBC1D2,MPP7,FBN1,THBS4,CDH17,FNBP1L,CDH2,SFN,LARP1,SHTN1,DOCK9 GO:0005215 transporter activity 0.00470473119199252 -5.35918663999083 1266 151 0.0898809523809524 1680 17224 10368,54847,55640,2898,10396,55283,3709,114134,785,28232,84679,23413,7881,3781,6567,5002,84068,347735,3790,7220,54805,154091,140738,83548,5360,2823,30818,6520,10257,285335,475,56704,81894,1244,3752,94081,83985,6541,27345,540,148808,150159,27012,9899,6331,57156,2561,6334,9481,90423,120103,6507,23209,255231,7782,23657,23461,783,153768,27166,4040,220963,79815,353189,728215,56901,54020,3786,206358,84725,11001,7436,6262,94015,10203,10577,26872,60598,55002,2900,84879,11182,1015,7222,114880,6542,10560,51310,1138,134429,27112,6326,92270,9312,6328,23507,27133,119559,64116,8973,481,57205,10052,23516,3839,41,3755,84976,160518,55129,256987,57088,6536,10079,3843,2566,2621,9990,2570,81855,3749,80723,90550,222553,219527,3761,6324,27094,55117,85414,490,54795,30061,777,2894,22821,23250,84804,114879,8140,116843,81796,2906,55356,6510,117247,781,493,9619,478,8501 CACNG3,SIDT1,FLVCR2,GRIK2,ATP8A1,MCOLN3,ITPR2,SLC2A13,CACNB4,SLCO3A1,SLC9A7,NCS1,KCNAB1,KCNN2,SLC16A2,SLC22A18,SLC10A7,SERINC2,KCNS3,TRPC1,CNNM2,SLC2A12,TMEM37,COG3,PLTP,GPM6A,KCNIP3,SLC3A2,ABCC4,SLC9C1,ATOX1,JPH1,SLC25A28,ABCC2,KCND3,SFXN1,SPNS1,SLC7A1,KCNMB4,ATP7B,MFSD4A,SLC9B1,KCNV1,SV2B,SCN5A,TMEM63C,GABRB2,SCN8A,SLC25A27,ATP6V1E2,SLC36A4,SLC1A3,MLC1,MCOLN2,SLC30A4,SLC7A11,ABCA5,CACNB2,PRELID2,PRELID1,LRP6,SLC16A9,NIPAL2,SLCO4C1,FAM155A,NDUFA4L2,SLC37A1,KCNQ3,SLC36A1,PLEKHA8,SLC27A2,VLDLR,RYR2,TTYH2,CALCRL,NPC2,STEAP1,KCNK15,TMCO3,GRIK4,MFSD2A,SLC2A6,CDH17,TRPC3,OSBPL6,SLC7A2,SLC19A2,SLC22A17,CHRNA5,STARD4,FAM155B,SCN2A,ATP6AP1L,KCNB2,SCN3A,LRRC8B,KCNH5,SFXN4,SLC39A8,CHRNA6,ATP1B1,ATP10D,GJC1,SLC39A14,KPNA3,ASIC1,KCNG1,DISP1,DENND5B,ANO10,SERINC5,PLSCR4,SLC6A9,ATP9A,IPO5,GABRG2,GAS6,SLC12A6,GABRR2,SFXN3,KCNC4,SLC35G2,MCU,SLC35F1,LRRC55,KCNJ4,SCN1B,KCNMB3,SLC6A15,SLC45A3,ATP2B1,TRPM4,SLC40A1,CACNA1E,GRID1,RASA3,ATP11A,MFSD9,OSBPL5,SLC7A5,SLC18B1,SLCO5A1,GRIN2D,SLC22A15,SLC1A5,SLC16A10,CACNA2D1,ATP2B4,ABCG1,ATP1A3,SLC43A1 GO:0060090 molecular adaptor activity 0.00479101971177869 -5.34101200675468 188 30 0.0178571428571429 1680 17224 10451,6452,10580,8935,2888,9047,287,2059,3092,3512,2621,10399,91947,8631,1832,7373,10458,1123,11161,1124,4130,143098,23767,142679,90525,1310,153090,84632,2887,9846 VAV3,SH3BP2,SORBS1,SKAP2,GRB14,SH2D2A,ANK2,EPS8,HIP1,JCHAIN,GAS6,RACK1,ARRDC4,SKAP1,DSP,COL14A1,BAIAP2,CHN1,ERG28,CHN2,MAP1A,MPP7,FLRT3,DUSP19,SHF,COL19A1,DAB2IP,AFAP1L2,GRB10,GAB2 GO:0016769 transferase activity, transferring nitrogenous groups 0.00499762817291572 -5.29879184451176 23 7 0.00416666666666667 1680 17224 84706,85007,2597,18,51166,2628,64850 GPT2,PHYKPL,GAPDH,ABAT,AADAT,GATM,ETNPPL GO:0042813 Wnt-activated receptor activity 0.00499762817291572 -5.29879184451176 23 7 0.00416666666666667 1680 17224 4040,23554,4919,8322,8325,4038,8321 LRP6,TSPAN12,ROR1,FZD4,FZD8,LRP4,FZD1 GO:0022838 substrate-specific channel activity 0.00506206816699036 -5.28598015053534 441 60 0.0357142857142857 1680 17224 27012,55129,6331,57156,10368,2898,2561,6334,55283,2566,3709,2621,2570,3749,785,23413,90550,255231,219527,3761,7881,1138,3781,6324,783,27094,3790,7220,140738,6326,27112,728215,9312,6328,54795,30061,2823,30818,3786,285335,23507,27133,777,56704,2894,6262,8973,94015,22821,3752,10052,2900,60598,27345,3755,41,2906,7222,781,160518 KCNV1,ANO10,SCN5A,TMEM63C,CACNG3,GRIK2,GABRB2,SCN8A,MCOLN3,GABRG2,ITPR2,GAS6,GABRR2,KCNC4,CACNB4,NCS1,MCU,MCOLN2,LRRC55,KCNJ4,KCNAB1,CHRNA5,KCNN2,SCN1B,CACNB2,KCNMB3,KCNS3,TRPC1,TMEM37,SCN2A,FAM155B,FAM155A,KCNB2,SCN3A,TRPM4,SLC40A1,GPM6A,KCNIP3,KCNQ3,SLC9C1,LRRC8B,KCNH5,CACNA1E,JPH1,GRID1,RYR2,CHRNA6,TTYH2,RASA3,KCND3,GJC1,GRIK4,KCNK15,KCNMB4,KCNG1,ASIC1,GRIN2D,TRPC3,CACNA2D1,DENND5B GO:0004364 glutathione transferase activity 0.00530626727573291 -5.23886665217698 35 9 0.00535714285714286 1680 17224 54332,2946,241,119391,4259,2948,2947,9446,9536 GDAP1,GSTM2,ALOX5AP,GSTO2,MGST3,GSTM4,GSTM3,GSTO1,PTGES GO:0004551 nucleotide diphosphatase activity 0.00564723569185013 -5.1765891116292 18 6 0.00357142857142857 1680 17224 5167,170685,2617,2272,83594,200035 ENPP1,NUDT10,GARS,FHIT,NUDT12,NUDT17 GO:0070064 proline-rich region binding 0.00564723569185013 -5.1765891116292 18 6 0.00357142857142857 1680 17224 10413,64762,322,4734,10458,2690 YAP1,GAREM1,APBB1,NEDD4,BAIAP2,GHR GO:0031994 insulin-like growth factor I binding 0.00578294618134229 -5.15284200620553 13 5 0.00297619047619048 1680 17224 3480,3489,3655,3690,3486 IGF1R,IGFBP6,ITGA6,ITGB3,IGFBP3 GO:0004712 protein serine/threonine/tyrosine kinase activity 0.00608247759946649 -5.10234316609735 42 10 0.00595238095238095 1680 17224 6446,5563,9149,10188,93,8444,6196,5602,5608,120892 SGK1,PRKAA2,DYRK1B,TNK2,ACVR2B,DYRK3,RPS6KA2,MAPK10,MAP2K6,LRRK2 GO:0000978 RNA polymerase II proximal promoter sequence-specific DNA binding 0.00636538545623094 -5.05688049008981 437 59 0.0351190476190476 1680 17224 64764,64919,11279,860,55893,5324,122953,5013,2625,6777,1050,51222,4825,93986,29841,2624,4609,6720,7020,5452,4091,2115,1052,2735,30062,30818,468,4212,3174,2649,11166,579,3164,4774,9516,10413,9935,100271849,23314,467,639,474,10538,7545,55509,53335,1051,4088,64324,138151,148523,688,3239,26257,63973,64754,10736,1649,4208 CREB3L2,BCL11B,KLF8,RUNX2,ZNF395,PLAG1,JDP2,OTX1,GATA3,STAT5B,CEBPA,ZNF219,NKX6-1,FOXP2,GRHL1,GATA2,MYC,SREBF1,TFAP2A,POU2F2,SMAD6,ETV1,CEBPD,GLI1,RAX,KCNIP3,ATF4,MEIS2,HNF4G,NR6A1,SOX21,NKX3-2,NR4A1,NFIA,LITAF,YAP1,MAFB,MEF2B,SATB2,ATF3,PRDM1,ATOH1,BATF,ZIC1,BATF3,BCL11A,CEBPB,SMAD3,NSD1,NACC2,CIART,KLF5,HOXD13,NKX2-8,NEUROG2,SMYD3,SIX2,DDIT3,MEF2C GO:0030552 cAMP binding 0.006471076480469 -5.04041280402012 24 7 0.00416666666666667 1680 17224 5577,5144,64208,11149,10846,9693,11069 PRKAR2B,PDE4D,POPDC3,BVES,PDE10A,RAPGEF2,RAPGEF4 GO:0035254 glutamate receptor binding 0.00666089966708355 -5.01150071840534 30 8 0.00476190476190476 1680 17224 54550,9495,22941,9455,3092,1740,821,9454 NECAB2,AKAP5,SHANK2,HOMER2,HIP1,DLG2,CANX,HOMER3 GO:0005518 collagen binding 0.00698490508435173 -4.96400387486207 63 13 0.00773809523809524 1680 17224 5058,4088,9902,2335,25890,147372,3673,150356,26577,871,780,7373,57211 PAK1,SMAD3,MRC2,FN1,ABI3BP,CCBE1,ITGA2,CHADL,PCOLCE2,SERPINH1,DDR1,COL14A1,ADGRG6 GO:0048365 Rac GTPase binding 0.00698490508435173 -4.96400387486207 63 13 0.00773809523809524 1680 17224 5058,10451,85440,10160,57144,2059,57580,57522,221178,5585,1794,9912,57531 PAK1,VAV3,DOCK7,FARP1,PAK5,EPS8,PREX1,SRGAP1,SPATA13,PKN1,DOCK2,ARHGAP44,HACE1 GO:0008289 lipid binding 0.00705702324684006 -4.95373195281554 716 90 0.0535714285714286 1680 17224 23092,5321,8448,91683,54477,4430,55283,3512,3709,255928,51429,54830,27445,1592,9372,2152,85477,1687,10247,10497,118987,57732,134429,2172,153090,134829,29993,7099,5360,29887,3306,10125,9846,2241,1604,4139,57580,4779,59338,6622,10400,5287,221749,4306,123036,9170,241,29091,55784,4983,6402,2621,5217,9912,10265,25851,8435,23263,154661,23678,93664,285590,79958,2242,51375,116984,4651,84725,117583,2104,9693,9265,29763,10979,3092,10577,9743,10333,23236,9227,3399,6456,115548,114879,55353,5337,54874,114880,9619,478 ARHGAP26,PLA2G4A,DOC2A,SYT12,PLEKHA5,MYO1B,MCOLN3,JCHAIN,ITPR2,SYT14,SNX9,NUP62CL,PCLO,CYP26A1,ZFYVE9,F3,SCIN,GSDME,RIDA,UNC13B,PDZD8,ZFYVE28,STARD4,FABP6,DAB2IP,CLVS2,PACSIN1,TLR4,PLTP,SNX10,HSPA2,RASGRP1,GAB2,FER,CD55,MARK1,PREX1,NFE2L1,PLEKHA1,SNCA,PEMT,PIK3C2B,PXDC1,NR3C2,TC2N,LPAR2,ALOX5AP,STXBP6,MCTP2,OPHN1,SELL,GAS6,PFN2,ARHGAP44,IRX5,TECPR1,SOAT2,MCF2L,RUNDC3B,SGK3,CADPS2,SH3PXD2B,DENND1C,FES,SNX7,ARAP2,MYO10,PLEKHA8,PARD3B,ESRRG,RAPGEF2,CYTH3,PACSIN3,FERMT2,HIP1,NPC2,ARHGAP32,TLR6,PLCB1,LRAT,ID3,SH3GL2,FCHO2,OSBPL5,LAPTM4B,PLD1,FNBP1L,OSBPL6,ABCG1,ATP1A3 GO:0017076 purine nucleotide binding 0.0078167534429762 -4.85148597137273 1854 211 0.125595238095238 1680 17224 349565,4598,2180,90,3798,10396,51175,445,5578,5881,16,8428,10382,5891,8153,9531,6196,1768,5911,25837,54805,2051,5567,5159,51062,10188,4139,10257,130399,120892,5577,1244,93,4919,10110,157,2770,9149,203,5167,10769,10827,540,2081,5603,148252,5287,144132,58528,5563,833,7301,26524,860,9886,11149,6334,9748,284716,65997,122622,26038,134266,116835,1938,3480,57143,23461,10846,5592,222537,112,80216,55137,375449,5058,2264,23433,4651,11001,11069,55437,84033,8476,55760,9261,57494,29941,11031,3099,162394,79646,387751,6296,92170,2042,26052,152110,29984,4430,5596,4916,1147,2870,23046,780,91351,10290,440,83694,140469,92,22989,5144,5874,4233,379,1767,3306,2241,91807,2617,7846,5163,5208,4597,53354,107,5588,481,23682,79739,2444,57205,260425,2260,7453,27010,953,64208,5579,2633,5754,84451,657,5413,5602,27314,22983,23043,4642,8444,659,57144,10079,54622,338323,402,3800,51655,5028,5585,2047,5580,30845,23551,2963,23678,59,6446,5593,79659,5106,4646,55964,22800,6850,2242,490,5210,54795,26873,5865,51560,9693,389643,81788,205,4141,116986,23250,2977,79834,57761,2268,390,5608,2775,10000,79858,138429,55605,3098,79705,2669,129607,23095,51776,493,9619,478 NMNAT3,MVK,ACSL1,ACVR1,KIF5A,ATP8A1,TUBE1,ASS1,PRKCA,RAC3,AARS,STK24,TUBB4A,MOK,RND2,BAG3,RPS6KA2,DNAH6,RAP2A,RAB26,CNNM2,EPHB6,PRKACB,PDGFRB,ATL1,TNK2,MARK1,ABCC4,ACVR1C,LRRK2,PRKAR2B,ABCC2,ACVR2B,ROR1,SGK2,GRK3,GNAI1,DYRK1B,AK1,ENPP1,PLK2,FAM114A2,ATP7B,ERN1,MAPK13,DIRAS1,PIK3C2B,DNHD1,RRAGD,PRKAA2,CARS,TYRO3,LATS2,RUNX2,RHOBTB1,BVES,SCN8A,SLK,RIMKLA,RASL11B,ADSSL1,CHD5,GRPEL2,HSPA12B,EEF2,IGF1R,ADCK1,ABCA5,PDE10A,PRKG1,HS3ST5,ADCY6,ALPK1,FIGN,MAST4,PAK1,FGFR4,RHOQ,MYO10,SLC27A2,RAPGEF4,STRADB,OBSCN,CDC42BPA,DHX32,MAPKAPK2,RIMKLB,PKN3,RAB31,HK2,SLFN5,PANK3,GVINP1,ACSM3,MTG1,EPHA3,DNM3,NEK10,RHOD,MYO1B,MAPK4,NTRK3,CHUK,GRK6,KIF21B,DDR1,DDX60L,SPEG,ASNS,RPS6KL1,MYO3B,ACVR2A,MYH15,PDE4D,RAB27B,MET,ARL4D,DNAH5,HSPA2,FER,MYLK3,GARS,TUBA1A,PDK1,PFKFB2,MVD,PANK1,ADCY1,PRKCQ,ATP1B1,RAB38,TTLL7,FRK,ATP10D,MAGI3,FGFR1,WARS,TPK1,ENTPD1,POPDC3,PRKCB,GBP1,PTK7,MAP3K21,BMPR1A,SEPT5,MAPK10,RAB30,MAST1,TNIK,MYO1D,DYRK3,BMPR2,PAK5,ATP9A,ARL15,NLRP14,ARL2,KIF5C,RASD1,P2RY1,PKN1,EPHB1,PRKCD,EHD3,RASD2,GTF2F2,SGK3,ACTA2,SGK1,PRKG2,DYNC2H1,PCK2,MYO6,SEPT3,RRAS2,SYK,FES,ATP2B1,PFKFB4,TRPM4,OPLAH,RAB3B,RAB6B,RAPGEF2,NUGGC,NUAK2,AK4,MARS,AGAP2,ATP11A,GUCY1A2,PEAK1,TRIB3,FGR,RND3,MAP2K6,GNAO1,AKT3,NEK11,PIP5KL1,KIF21A,HK1,LRRK1,GEM,CMPK2,KIF1B,MAP3K20,ATP2B4,ABCG1,ATP1A3 GO:0016835 carbon-oxygen lyase activity 0.00792198933455366 -4.83811292609061 71 14 0.00833333333333333 1680 17224 760,1962,2026,7390,200558,9200,48,2194,875,23483,767,2023,64850,377677 CA2,EHHADH,ENO2,UROS,APLF,HACD1,ACO1,FASN,CBS,TGDS,CA8,ENO1,ETNPPL,CA13 GO:0005070 SH3/SH2 adaptor activity 0.0079493893009173 -4.83466017076119 57 12 0.00714285714285714 1680 17224 1123,10451,6452,1124,10580,8935,9047,2888,2059,90525,2887,8631 CHN1,VAV3,SH3BP2,CHN2,SORBS1,SKAP2,SH2D2A,GRB14,EPS8,SHF,GRB10,SKAP1 GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication 0.00796396937106661 -4.83282773871091 5 3 0.00178571428571429 1680 17224 5318,1832,1829 PKP2,DSP,DSG2 GO:0019838 growth factor binding 0.00797786147689438 -4.83108488878649 131 22 0.0130952380952381 1680 17224 2264,6331,90,10626,3489,659,51232,8838,130399,3655,4916,93,2260,7049,3480,3690,92,8829,3977,5159,5046,3486 FGFR4,SCN5A,ACVR1,TRIM16,IGFBP6,BMPR2,CRIM1,WISP3,ACVR1C,ITGA6,NTRK3,ACVR2B,FGFR1,TGFBR3,IGF1R,ITGB3,ACVR2A,NRP1,LIFR,PDGFRB,PCSK6,IGFBP3 GO:0016758 transferase activity, transferring hexosyl groups 0.00844440443009192 -4.774251254585 212 32 0.019047619047619 1680 17224 90693,7368,11226,79695,64131,200810,114805,22856,146664,2589,1890,26301,10690,4245,178,374378,144245,9331,337876,8708,2651,11282,23127,64409,79623,283358,283417,2591,5352,8707,440138,11285 CCDC126,UGT8,GALNT6,GALNT12,XYLT1,ALG1L,GALNT13,CHSY1,MGAT5B,GALNT1,TYMP,GBGT1,FUT9,MGAT1,AGL,GALNT18,ALG10B,B4GALT6,CHSY3,B3GALT1,GCNT2,MGAT4B,COLGALT2,GALNT17,GALNT14,B4GALNT3,DPY19L2,GALNT3,PLOD2,B3GALT2,ALG11,B4GALT7 GO:0000987 proximal promoter sequence-specific DNA binding 0.00851496262864231 -4.76593035376234 452 60 0.0357142857142857 1680 17224 64764,64919,11279,860,9658,55893,5324,122953,5013,2625,6777,1050,51222,4825,93986,29841,2624,4609,6720,7020,5452,4091,2115,1052,2735,30062,30818,468,4212,3174,2649,11166,579,3164,4774,9516,10413,9935,100271849,23314,467,639,474,10538,7545,55509,53335,1051,4088,64324,138151,148523,688,3239,26257,63973,64754,10736,1649,4208 CREB3L2,BCL11B,KLF8,RUNX2,ZNF516,ZNF395,PLAG1,JDP2,OTX1,GATA3,STAT5B,CEBPA,ZNF219,NKX6-1,FOXP2,GRHL1,GATA2,MYC,SREBF1,TFAP2A,POU2F2,SMAD6,ETV1,CEBPD,GLI1,RAX,KCNIP3,ATF4,MEIS2,HNF4G,NR6A1,SOX21,NKX3-2,NR4A1,NFIA,LITAF,YAP1,MAFB,MEF2B,SATB2,ATF3,PRDM1,ATOH1,BATF,ZIC1,BATF3,BCL11A,CEBPB,SMAD3,NSD1,NACC2,CIART,KLF5,HOXD13,NKX2-8,NEUROG2,SMYD3,SIX2,DDIT3,MEF2C GO:0016757 transferase activity, transferring glycosyl groups 0.0093211255220275 -4.67547189341 289 41 0.0244047619047619 1680 17224 90693,727936,7368,79695,11226,6480,64131,200810,114805,22856,146664,23475,2589,1890,26301,56952,10690,4245,6489,178,374378,144245,9331,83666,337876,145173,8708,2651,4860,11282,23127,64409,256435,283358,79623,2591,283417,5352,8707,440138,11285 CCDC126,GXYLT2,UGT8,GALNT12,GALNT6,ST6GAL1,XYLT1,ALG1L,GALNT13,CHSY1,MGAT5B,QPRT,GALNT1,TYMP,GBGT1,PRTFDC1,FUT9,MGAT1,ST8SIA1,AGL,GALNT18,ALG10B,B4GALT6,PARP9,CHSY3,B3GLCT,B3GALT1,GCNT2,PNP,MGAT4B,COLGALT2,GALNT17,ST6GALNAC3,B4GALNT3,GALNT14,GALNT3,DPY19L2,PLOD2,B3GALT2,ALG11,B4GALT7 GO:0004320 oleoyl-[acyl-carrier-protein] hydrolase activity 0.0095086127254072 -4.65555728841719 2 2 0.00119047619047619 1680 17224 55301,2194 OLAH,FASN GO:0016295 myristoyl-[acyl-carrier-protein] hydrolase activity 0.0095086127254072 -4.65555728841719 2 2 0.00119047619047619 1680 17224 55301,2194 OLAH,FASN GO:0045174 glutathione dehydrogenase (ascorbate) activity 0.0095086127254072 -4.65555728841719 2 2 0.00119047619047619 1680 17224 9446,119391 GSTO1,GSTO2 GO:0072590 N-acetyl-L-aspartate-L-glutamate ligase activity 0.0095086127254072 -4.65555728841719 2 2 0.00119047619047619 1680 17224 57494,284716 RIMKLB,RIMKLA GO:0016296 palmitoyl-[acyl-carrier-protein] hydrolase activity 0.0095086127254072 -4.65555728841719 2 2 0.00119047619047619 1680 17224 55301,2194 OLAH,FASN GO:0047275 glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity 0.0095086127254072 -4.65555728841719 2 2 0.00119047619047619 1680 17224 8708,8707 B3GALT1,B3GALT2 GO:0016524 latrotoxin receptor activity 0.0095086127254072 -4.65555728841719 2 2 0.00119047619047619 1680 17224 23266,22859 ADGRL2,ADGRL1 GO:0034437 glycoprotein transporter activity 0.0095086127254072 -4.65555728841719 2 2 0.00119047619047619 1680 17224 7436,9619 VLDLR,ABCG1 GO:0016404 15-hydroxyprostaglandin dehydrogenase (NAD+) activity 0.0095086127254072 -4.65555728841719 2 2 0.00119047619047619 1680 17224 3248,10257 HPGD,ABCC4 GO:0016155 formyltetrahydrofolate dehydrogenase activity 0.0095086127254072 -4.65555728841719 2 2 0.00119047619047619 1680 17224 160428,10840 ALDH1L2,ALDH1L1 GO:0016297 acyl-[acyl-carrier-protein] hydrolase activity 0.0095086127254072 -4.65555728841719 2 2 0.00119047619047619 1680 17224 55301,2194 OLAH,FASN GO:0086062 voltage-gated sodium channel activity involved in Purkinje myocyte action potential 0.0095086127254072 -4.65555728841719 2 2 0.00119047619047619 1680 17224 6331,6324 SCN5A,SCN1B GO:0035403 histone kinase activity (H3-T6 specific) 0.0095086127254072 -4.65555728841719 2 2 0.00119047619047619 1680 17224 5578,5579 PRKCA,PRKCB GO:0016362 activin receptor activity, type II 0.0095086127254072 -4.65555728841719 2 2 0.00119047619047619 1680 17224 93,659 ACVR2B,BMPR2 GO:0050610 methylarsonate reductase activity 0.0095086127254072 -4.65555728841719 2 2 0.00119047619047619 1680 17224 9446,119391 GSTO1,GSTO2 GO:0004692 cGMP-dependent protein kinase activity 0.0095086127254072 -4.65555728841719 2 2 0.00119047619047619 1680 17224 5593,5592 PRKG2,PRKG1 GO:0017075 syntaxin-1 binding 0.00995354676532514 -4.60982633250134 20 6 0.00357142857142857 1680 17224 6616,10497,6812,120892,55638,9751 SNAP25,UNC13B,STXBP1,LRRK2,SYBU,SNPH GO:0016740 transferase activity 0.010206072181284 -4.58477242392915 2446 271 0.161309523809524 1680 17224 727936,23077,90,200810,6777,5578,54855,8428,143279,5891,1890,114907,7049,2947,114818,54332,26249,130399,151230,56062,160428,120892,93,8822,79683,57630,10769,8707,5603,92126,8829,26524,241,6480,9748,55301,55008,2122,26301,118788,57143,5592,80216,6489,375449,178,220441,4860,4259,2194,23127,7468,256435,8476,119391,29941,57161,54814,4355,126433,64754,6296,2042,685,6785,79783,9781,11226,79695,5596,1147,2870,780,1040,10290,55603,399818,10840,64219,2628,1787,2597,91807,8708,5163,153830,5208,27133,53354,5588,2260,260425,8660,5579,10400,84451,440138,9953,657,9474,401265,5602,4281,57531,23464,51191,5585,2047,26262,4734,3157,348751,8435,4245,23678,5593,85007,79603,2242,9331,83666,5210,2946,123688,171425,56895,4354,83401,158866,205,2591,57761,64324,2268,7015,5352,10000,79858,283209,138429,79705,3098,10715,129607,8945,11285,90693,349565,23321,4598,7368,146664,18,9486,23475,6196,51166,2051,374378,5159,5567,10188,4139,2651,4919,10110,22838,157,9149,114088,203,2081,5287,143384,266722,10090,84706,91694,5563,7301,55034,26272,79993,114805,22856,50862,2202,2589,285671,56952,3480,8139,222537,9443,25827,5058,2264,337876,11043,145173,81790,2948,11282,1944,55437,84033,64409,639,283358,9261,3099,79845,79646,5071,152110,54947,64131,57520,11237,4916,9920,83852,83694,64429,140469,254887,92,4233,57110,144245,1491,2241,59336,54941,9446,2444,64850,27010,5903,154214,60468,5754,3082,55819,129642,22983,23043,8444,659,90293,57144,221078,56978,10690,5580,10612,6446,115123,6850,51232,81788,79834,79623,9227,4255,283417,5608,1740,114804,51776,9536 GXYLT2,MYCBP2,ACVR1,ALG1L,STAT5B,PRKCA,TENT5C,STK24,HECTD2,MOK,TYMP,FBXO32,TGFBR3,GSTM3,KLHL29,GDAP1,KLHL3,ACVR1C,KLHL23,KLHL4,ALDH1L2,LRRK2,ACVR2B,FGF17,ZDHHC14,SH3RF1,PLK2,B3GALT2,MAPK13,DSEL,NRP1,LATS2,ALOX5AP,ST6GAL1,SLK,OLAH,HERC6,MECOM,GBGT1,PIK3AP1,ADCK1,PRKG1,ALPK1,ST8SIA1,MAST4,AGL,RNF152,PNP,MGST3,FASN,COLGALT2,NSD2,ST6GALNAC3,CDC42BPA,GSTO2,PKN3,PELI2,QPCTL,MPP2,FBXO27,SMYD3,ACSM3,EPHA3,BTC,ELOVL4,SUGCT,RNF144A,GALNT6,GALNT12,MAPK4,CHUK,GRK6,DDR1,CDS1,SPEG,TENT5A,EEF1AKMT2,ALDH1L1,PJA1,GATM,TRDMT1,GAPDH,MYLK3,B3GALT1,PDK1,RNF145,PFKFB2,KCNH5,PANK1,PRKCQ,FGFR1,MAGI3,IRS2,PRKCB,PEMT,MAP3K21,ALG11,HS3ST3B1,BMPR1A,ATG5,KLHL31,MAPK10,MID1,HACE1,GCAT,HERC5,PKN1,EPHB1,TSPAN17,NEDD4,HMGCS1,FTCDNL1,SOAT2,MGAT1,SGK3,PRKG2,PHYKPL,CERS4,FES,B4GALT6,PARP9,PFKFB4,GSTM2,HYKK,CLYBL,AGPAT4,MPP1,ELOVL3,ZDHHC15,AK4,GALNT3,TRIB3,NSD1,FGR,TERT,PLOD2,AKT3,NEK11,PGM2L1,PIP5KL1,LRRK1,HK1,CERS1,CMPK2,BTRC,B4GALT7,CCDC126,NMNAT3,TRIM2,MVK,UGT8,MGAT5B,ABAT,CHST10,QPRT,RPS6KA2,AADAT,EPHB6,GALNT18,PDGFRB,PRKACB,TNK2,MARK1,GCNT2,ROR1,SGK2,RNF44,GRK3,DYRK1B,TRIM9,AK1,ERN1,PIK3C2B,CACUL1,HS6ST3,UST,GPT2,LONRF1,PRKAA2,TYRO3,MOCOS,FBXO4,ELOVL7,GALNT13,CHSY1,RNF141,EFEMP1,GALNT1,RNF180,PRTFDC1,IGF1R,GAN,HS3ST5,MED7,FBXL2,PAK1,FGFR4,CHSY3,MID2,B3GLCT,RNF170,GSTM4,MGAT4B,EFNA3,STRADB,OBSCN,GALNT17,PRDM1,B4GALNT3,MAPKAPK2,HK2,RNF122,PANK3,PRKN,NEK10,LPCAT2,XYLT1,HECW2,RNF24,NTRK3,KBTBD11,SETDB2,RPS6KL1,ZDHHC6,MYO3B,ZDHHC23,ACVR2A,MET,HRASLS,ALG10B,CTH,FER,PRDM13,RNF125,GSTO1,FRK,ETNPPL,TPK1,RANBP2,RNF217,BACH2,PTK7,HGF,RNF130,MBOAT2,MAST1,TNIK,DYRK3,BMPR2,KLHL13,PAK5,NSUN6,PRDM8,FUT9,PRKCD,TRIM3,SGK1,MARCH3,SYK,CRIM1,NUAK2,PEAK1,GALNT14,LRAT,MGMT,DPY19L2,MAP2K6,DLG2,RNF157,MAP3K20,PTGES GO:0019201 nucleotide kinase activity 0.0103511511047508 -4.57065754760469 26 7 0.00416666666666667 1680 17224 205,203,1740,129607,4354,260425,4355 AK4,AK1,DLG2,CMPK2,MPP1,MAGI3,MPP2 GO:0032555 purine ribonucleotide binding 0.0108857807373518 -4.52029786088235 1840 208 0.123809523809524 1680 17224 349565,4598,2180,90,3798,10396,51175,445,5578,5881,16,8428,10382,5891,8153,6196,1768,5911,25837,54805,2051,5567,5159,51062,10188,4139,10257,130399,120892,5577,1244,93,4919,10110,157,2770,9149,203,5167,10769,540,2081,5603,148252,5287,144132,58528,5563,833,7301,26524,860,9886,11149,6334,9748,284716,65997,122622,26038,116835,1938,3480,57143,23461,10846,5592,222537,112,80216,55137,375449,5058,2264,23433,4651,11001,11069,55437,84033,8476,55760,9261,57494,29941,11031,3099,162394,79646,387751,6296,92170,2042,26052,152110,29984,4430,5596,4916,1147,2870,23046,780,91351,10290,440,83694,140469,92,22989,5144,5874,4233,379,1767,3306,2241,91807,2617,7846,5163,5208,4597,53354,107,5588,481,23682,2444,79739,57205,260425,2260,7453,27010,953,64208,5579,2633,5754,84451,657,5413,5602,27314,22983,23043,4642,8444,659,57144,10079,54622,338323,402,3800,51655,5028,5585,2047,5580,30845,23551,2963,23678,59,6446,5593,79659,5106,4646,55964,22800,6850,2242,490,5210,54795,26873,5865,51560,9693,389643,81788,205,4141,116986,23250,2977,79834,57761,2268,390,5608,2775,10000,79858,138429,55605,3098,79705,2669,129607,23095,51776,493,9619,478 NMNAT3,MVK,ACSL1,ACVR1,KIF5A,ATP8A1,TUBE1,ASS1,PRKCA,RAC3,AARS,STK24,TUBB4A,MOK,RND2,RPS6KA2,DNAH6,RAP2A,RAB26,CNNM2,EPHB6,PRKACB,PDGFRB,ATL1,TNK2,MARK1,ABCC4,ACVR1C,LRRK2,PRKAR2B,ABCC2,ACVR2B,ROR1,SGK2,GRK3,GNAI1,DYRK1B,AK1,ENPP1,PLK2,ATP7B,ERN1,MAPK13,DIRAS1,PIK3C2B,DNHD1,RRAGD,PRKAA2,CARS,TYRO3,LATS2,RUNX2,RHOBTB1,BVES,SCN8A,SLK,RIMKLA,RASL11B,ADSSL1,CHD5,HSPA12B,EEF2,IGF1R,ADCK1,ABCA5,PDE10A,PRKG1,HS3ST5,ADCY6,ALPK1,FIGN,MAST4,PAK1,FGFR4,RHOQ,MYO10,SLC27A2,RAPGEF4,STRADB,OBSCN,CDC42BPA,DHX32,MAPKAPK2,RIMKLB,PKN3,RAB31,HK2,SLFN5,PANK3,GVINP1,ACSM3,MTG1,EPHA3,DNM3,NEK10,RHOD,MYO1B,MAPK4,NTRK3,CHUK,GRK6,KIF21B,DDR1,DDX60L,SPEG,ASNS,RPS6KL1,MYO3B,ACVR2A,MYH15,PDE4D,RAB27B,MET,ARL4D,DNAH5,HSPA2,FER,MYLK3,GARS,TUBA1A,PDK1,PFKFB2,MVD,PANK1,ADCY1,PRKCQ,ATP1B1,RAB38,FRK,TTLL7,ATP10D,MAGI3,FGFR1,WARS,TPK1,ENTPD1,POPDC3,PRKCB,GBP1,PTK7,MAP3K21,BMPR1A,SEPT5,MAPK10,RAB30,MAST1,TNIK,MYO1D,DYRK3,BMPR2,PAK5,ATP9A,ARL15,NLRP14,ARL2,KIF5C,RASD1,P2RY1,PKN1,EPHB1,PRKCD,EHD3,RASD2,GTF2F2,SGK3,ACTA2,SGK1,PRKG2,DYNC2H1,PCK2,MYO6,SEPT3,RRAS2,SYK,FES,ATP2B1,PFKFB4,TRPM4,OPLAH,RAB3B,RAB6B,RAPGEF2,NUGGC,NUAK2,AK4,MARS,AGAP2,ATP11A,GUCY1A2,PEAK1,TRIB3,FGR,RND3,MAP2K6,GNAO1,AKT3,NEK11,PIP5KL1,KIF21A,HK1,LRRK1,GEM,CMPK2,KIF1B,MAP3K20,ATP2B4,ABCG1,ATP1A3 GO:0015267 channel activity 0.0111784781393109 -4.49376494401717 467 61 0.0363095238095238 1680 17224 27012,55129,6331,57156,10368,2898,2561,6334,55283,2566,3709,2621,2570,3749,785,23413,90550,255231,219527,3761,7881,1138,3781,6324,783,27094,3790,7220,140738,6326,27112,728215,9312,6328,54795,30061,2823,30818,3786,285335,23507,27133,777,56704,2894,6262,8973,94015,22821,3752,26872,10052,60598,2900,27345,3755,41,2906,7222,781,160518 KCNV1,ANO10,SCN5A,TMEM63C,CACNG3,GRIK2,GABRB2,SCN8A,MCOLN3,GABRG2,ITPR2,GAS6,GABRR2,KCNC4,CACNB4,NCS1,MCU,MCOLN2,LRRC55,KCNJ4,KCNAB1,CHRNA5,KCNN2,SCN1B,CACNB2,KCNMB3,KCNS3,TRPC1,TMEM37,SCN2A,FAM155B,FAM155A,KCNB2,SCN3A,TRPM4,SLC40A1,GPM6A,KCNIP3,KCNQ3,SLC9C1,LRRC8B,KCNH5,CACNA1E,JPH1,GRID1,RYR2,CHRNA6,TTYH2,RASA3,KCND3,STEAP1,GJC1,KCNK15,GRIK4,KCNMB4,KCNG1,ASIC1,GRIN2D,TRPC3,CACNA2D1,DENND5B GO:0030551 cyclic nucleotide binding 0.0111798958518713 -4.49363812687359 39 9 0.00535714285714286 1680 17224 5593,5577,5144,64208,11149,10846,9693,11069,5592 PRKG2,PRKAR2B,PDE4D,POPDC3,BVES,PDE10A,RAPGEF2,RAPGEF4,PRKG1 GO:0022803 passive transmembrane transporter activity 0.011668572310902 -4.45085617856506 468 61 0.0363095238095238 1680 17224 27012,55129,6331,57156,10368,2898,2561,6334,55283,2566,3709,2621,2570,3749,785,23413,90550,255231,219527,3761,7881,1138,3781,6324,783,27094,3790,7220,140738,6326,27112,728215,9312,6328,54795,30061,2823,30818,3786,285335,23507,27133,777,56704,2894,6262,8973,94015,22821,3752,26872,10052,60598,2900,27345,3755,41,2906,7222,781,160518 KCNV1,ANO10,SCN5A,TMEM63C,CACNG3,GRIK2,GABRB2,SCN8A,MCOLN3,GABRG2,ITPR2,GAS6,GABRR2,KCNC4,CACNB4,NCS1,MCU,MCOLN2,LRRC55,KCNJ4,KCNAB1,CHRNA5,KCNN2,SCN1B,CACNB2,KCNMB3,KCNS3,TRPC1,TMEM37,SCN2A,FAM155B,FAM155A,KCNB2,SCN3A,TRPM4,SLC40A1,GPM6A,KCNIP3,KCNQ3,SLC9C1,LRRC8B,KCNH5,CACNA1E,JPH1,GRID1,RYR2,CHRNA6,TTYH2,RASA3,KCND3,STEAP1,GJC1,KCNK15,GRIK4,KCNMB4,KCNG1,ASIC1,GRIN2D,TRPC3,CACNA2D1,DENND5B GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding 0.0117016356659586 -4.44802664644032 10 4 0.00238095238095238 1680 17224 153090,25827,118788,5783 DAB2IP,FBXL2,PIK3AP1,PTPN13 GO:0005351 carbohydrate:proton symporter activity 0.0117016356659586 -4.44802664644032 10 4 0.00238095238095238 1680 17224 154091,114134,85414,11182 SLC2A12,SLC2A13,SLC45A3,SLC2A6 GO:0015179 L-amino acid transmembrane transporter activity 0.0119917522898839 -4.42353617467572 60 12 0.00714285714285714 1680 17224 6541,256987,6536,23657,206358,347735,8140,120103,6507,6542,6510,8501 SLC7A1,SERINC5,SLC6A9,SLC7A11,SLC36A1,SERINC2,SLC7A5,SLC36A4,SLC1A3,SLC7A2,SLC1A5,SLC43A1 GO:0030234 enzyme regulator activity 0.0120509697795925 -4.41861014264955 1037 123 0.0732142857142857 1680 17224 23092,116154,27344,57718,2258,9462,1793,8434,720,5611,58504,8601,4869,10144,23329,1794,26230,6497,55296,113622,9531,57568,9858,154043,153090,5521,5627,26577,871,11123,9353,10125,3486,11138,10188,83667,2597,1447,1285,120892,55531,57580,5577,7481,481,125058,6622,7453,55450,5903,3627,57584,10718,51704,27018,3071,6001,142679,79822,5274,8829,50859,6004,241,2335,9515,23216,9826,3843,4983,402,2621,29899,6000,11005,134266,9912,5523,84144,1123,26575,1124,10129,23767,5580,57522,4040,57186,84632,26034,285590,54206,23158,10253,83666,91272,92597,10451,54453,93974,116984,51232,54885,9693,55616,26086,22821,116986,9749,9743,10399,23236,55357,4324,57761,577,23677,9882,4325,54997,493,2810,5569 ARHGAP26,PHACTR3,PCSK1N,PPP4R4,FGF13,RASAL2,DOCK1,RECK,C4A,DNAJC3,ARHGAP22,RGS20,NPM1,FAM13A,TBC1D30,DOCK2,TIAM2,SKI,TBC1D19,ADPRHL1,BAG3,SIPA1L2,PPP1R26,CNKSR3,DAB2IP,PPP2R2B,PROS1,PCOLCE2,SERPINH1,RCAN3,SLIT2,RASGRP1,IGFBP3,TBC1D8,TNK2,SESN2,GAPDH,CSN2,COL4A3,LRRK2,ELMOD1,PREX1,PRKAR2B,WNT11,ATP1B1,TBC1D16,SNCA,WARS,CAMK2N1,RANBP2,CXCL10,ARHGAP21,NRG3,GPRC5B,BEX3,NCKAP1L,RGS10,DUSP19,ARHGAP28,SERPINI1,NRP1,SPOCK3,RGS16,ALOX5AP,FN1,STXBP5L,TBC1D1,ARHGEF11,IPO5,OPHN1,ARL2,GAS6,GPSM2,RGS7,SPINK5,GRPEL2,ARHGAP44,PPP2R3A,SYDE2,CHN1,RGS17,CHN2,FRY,FLRT3,PRKCD,SRGAP1,LRP6,RALGAPA2,AFAP1L2,IPCEF1,SH3PXD2B,ERRFI1,TBC1D9,SPRY2,PARP9,BOD1,MOB1B,VAV3,RIN2,ATP5IF1,ARAP2,CRIM1,TBC1D8B,RAPGEF2,ASAP3,GPSM1,RASA3,AGAP2,PHACTR2,ARHGAP32,RACK1,PLCB1,TBC1D2,MMP15,TRIB3,ADGRB3,SH3BP4,TBC1D4,MMP16,TESC,ATP2B4,SFN,PKIA GO:0032553 ribonucleotide binding 0.012238320789081 -4.40318320174399 1855 209 0.124404761904762 1680 17224 349565,4598,2180,90,3798,10396,51175,445,5578,5881,16,8428,10382,5891,8153,6196,1768,5911,25837,54805,2051,5567,5159,51062,10188,4139,10257,130399,120892,5577,1244,93,4919,10110,157,2770,9149,203,5167,10769,540,2081,5603,148252,5287,144132,58528,5563,833,7301,26524,860,9886,11149,6334,9748,284716,65997,122622,26038,116835,1938,3480,57143,23461,10846,5592,222537,112,80216,55137,375449,4846,5058,2264,23433,4651,11001,11069,55437,84033,8476,55760,9261,57494,29941,11031,3099,162394,79646,387751,6296,92170,2042,26052,152110,29984,4430,5596,4916,1147,2870,23046,780,91351,10290,440,83694,140469,92,22989,5144,5874,4233,379,1767,3306,2241,91807,2617,7846,5163,5208,4597,53354,107,5588,481,23682,79739,2444,57205,260425,2260,7453,27010,953,64208,5579,2633,5754,84451,657,5413,5602,27314,22983,23043,4642,8444,659,57144,10079,54622,338323,402,3800,51655,5028,5585,2047,5580,30845,23551,2963,23678,59,6446,5593,79659,5106,4646,55964,22800,6850,2242,490,5210,54795,26873,5865,51560,9693,389643,81788,205,4141,116986,23250,2977,79834,57761,2268,390,5608,2775,10000,79858,138429,55605,3098,79705,2669,129607,23095,51776,493,9619,478 NMNAT3,MVK,ACSL1,ACVR1,KIF5A,ATP8A1,TUBE1,ASS1,PRKCA,RAC3,AARS,STK24,TUBB4A,MOK,RND2,RPS6KA2,DNAH6,RAP2A,RAB26,CNNM2,EPHB6,PRKACB,PDGFRB,ATL1,TNK2,MARK1,ABCC4,ACVR1C,LRRK2,PRKAR2B,ABCC2,ACVR2B,ROR1,SGK2,GRK3,GNAI1,DYRK1B,AK1,ENPP1,PLK2,ATP7B,ERN1,MAPK13,DIRAS1,PIK3C2B,DNHD1,RRAGD,PRKAA2,CARS,TYRO3,LATS2,RUNX2,RHOBTB1,BVES,SCN8A,SLK,RIMKLA,RASL11B,ADSSL1,CHD5,HSPA12B,EEF2,IGF1R,ADCK1,ABCA5,PDE10A,PRKG1,HS3ST5,ADCY6,ALPK1,FIGN,MAST4,NOS3,PAK1,FGFR4,RHOQ,MYO10,SLC27A2,RAPGEF4,STRADB,OBSCN,CDC42BPA,DHX32,MAPKAPK2,RIMKLB,PKN3,RAB31,HK2,SLFN5,PANK3,GVINP1,ACSM3,MTG1,EPHA3,DNM3,NEK10,RHOD,MYO1B,MAPK4,NTRK3,CHUK,GRK6,KIF21B,DDR1,DDX60L,SPEG,ASNS,RPS6KL1,MYO3B,ACVR2A,MYH15,PDE4D,RAB27B,MET,ARL4D,DNAH5,HSPA2,FER,MYLK3,GARS,TUBA1A,PDK1,PFKFB2,MVD,PANK1,ADCY1,PRKCQ,ATP1B1,RAB38,TTLL7,FRK,ATP10D,MAGI3,FGFR1,WARS,TPK1,ENTPD1,POPDC3,PRKCB,GBP1,PTK7,MAP3K21,BMPR1A,SEPT5,MAPK10,RAB30,MAST1,TNIK,MYO1D,DYRK3,BMPR2,PAK5,ATP9A,ARL15,NLRP14,ARL2,KIF5C,RASD1,P2RY1,PKN1,EPHB1,PRKCD,EHD3,RASD2,GTF2F2,SGK3,ACTA2,SGK1,PRKG2,DYNC2H1,PCK2,MYO6,SEPT3,RRAS2,SYK,FES,ATP2B1,PFKFB4,TRPM4,OPLAH,RAB3B,RAB6B,RAPGEF2,NUGGC,NUAK2,AK4,MARS,AGAP2,ATP11A,GUCY1A2,PEAK1,TRIB3,FGR,RND3,MAP2K6,GNAO1,AKT3,NEK11,PIP5KL1,KIF21A,HK1,LRRK1,GEM,CMPK2,KIF1B,MAP3K20,ATP2B4,ABCG1,ATP1A3 GO:1901681 sulfur compound binding 0.0134841512955619 -4.30624026129639 236 34 0.0202380952380952 1680 17224 10178,2335,3075,6402,875,7049,8435,25890,84570,222537,2947,26577,9353,5046,2264,2946,2660,8838,2948,55753,6262,10082,2260,27010,3627,5167,2200,9508,7060,3673,5802,652,8829,9536 TENM1,FN1,CFH,SELL,CBS,TGFBR3,SOAT2,ABI3BP,COL25A1,HS3ST5,GSTM3,PCOLCE2,SLIT2,PCSK6,FGFR4,GSTM2,MSTN,WISP3,GSTM4,OGDHL,RYR2,GPC6,FGFR1,TPK1,CXCL10,ENPP1,FBN1,ADAMTS3,THBS4,ITGA2,PTPRS,BMP4,NRP1,PTGES GO:0097367 carbohydrate derivative binding 0.0137071357652898 -4.28983872296763 2160 240 0.142857142857143 1680 17224 349565,4598,2180,90,3798,10396,51175,445,3512,63827,5578,5881,16,8428,10382,5891,8153,6196,7049,25890,1768,5911,25837,54805,2051,26577,7099,9353,5567,5159,51062,10188,4139,10257,23670,130399,8838,120892,5577,1244,93,4919,10110,157,10082,2770,9149,203,5167,10855,10769,540,2081,5603,148252,5287,8829,144132,50859,58528,5563,833,7301,26524,860,2335,9886,11149,6334,9748,284716,65997,122622,26038,116835,1938,3480,57143,23461,10846,5592,222537,112,80216,55137,375449,4846,5058,2264,50512,23433,4860,2660,4651,11001,84725,11069,55437,84033,8476,55760,9261,57494,9508,29941,7060,11031,3099,162394,79646,387751,6296,92170,2042,26052,152110,3075,29984,4430,1147,5596,4916,2870,23046,780,91351,10290,440,84570,83694,140469,92,22989,5144,5874,4233,379,1767,3306,2241,91807,2617,7846,5163,5208,4597,53354,107,5588,481,23682,79739,2444,57205,260425,2260,7453,27010,953,3627,64208,5579,2633,5754,3673,84451,5802,657,5413,5602,27314,22983,10178,23043,4642,8444,659,57144,10079,54622,338323,402,3800,6402,51655,5028,5585,2047,5580,30845,23551,2963,23678,59,6446,5593,79659,5106,4646,55964,22800,6850,2242,490,5046,83666,5210,54795,26873,5865,51560,9693,389643,81788,205,4141,116986,23250,2977,79834,57761,2268,390,2200,5608,2775,10000,79858,138429,55605,3098,79705,652,2669,129607,23095,51776,493,9619,478 NMNAT3,MVK,ACSL1,ACVR1,KIF5A,ATP8A1,TUBE1,ASS1,JCHAIN,BCAN,PRKCA,RAC3,AARS,STK24,TUBB4A,MOK,RND2,RPS6KA2,TGFBR3,ABI3BP,DNAH6,RAP2A,RAB26,CNNM2,EPHB6,PCOLCE2,TLR4,SLIT2,PRKACB,PDGFRB,ATL1,TNK2,MARK1,ABCC4,CEMIP2,ACVR1C,WISP3,LRRK2,PRKAR2B,ABCC2,ACVR2B,ROR1,SGK2,GRK3,GPC6,GNAI1,DYRK1B,AK1,ENPP1,HPSE,PLK2,ATP7B,ERN1,MAPK13,DIRAS1,PIK3C2B,NRP1,DNHD1,SPOCK3,RRAGD,PRKAA2,CARS,TYRO3,LATS2,RUNX2,FN1,RHOBTB1,BVES,SCN8A,SLK,RIMKLA,RASL11B,ADSSL1,CHD5,HSPA12B,EEF2,IGF1R,ADCK1,ABCA5,PDE10A,PRKG1,HS3ST5,ADCY6,ALPK1,FIGN,MAST4,NOS3,PAK1,FGFR4,PODXL2,RHOQ,PNP,MSTN,MYO10,SLC27A2,PLEKHA8,RAPGEF4,STRADB,OBSCN,CDC42BPA,DHX32,MAPKAPK2,RIMKLB,ADAMTS3,PKN3,THBS4,RAB31,HK2,SLFN5,PANK3,GVINP1,ACSM3,MTG1,EPHA3,DNM3,NEK10,CFH,RHOD,MYO1B,CHUK,MAPK4,NTRK3,GRK6,KIF21B,DDR1,DDX60L,SPEG,ASNS,COL25A1,RPS6KL1,MYO3B,ACVR2A,MYH15,PDE4D,RAB27B,MET,ARL4D,DNAH5,HSPA2,FER,MYLK3,GARS,TUBA1A,PDK1,PFKFB2,MVD,PANK1,ADCY1,PRKCQ,ATP1B1,RAB38,TTLL7,FRK,ATP10D,MAGI3,FGFR1,WARS,TPK1,ENTPD1,CXCL10,POPDC3,PRKCB,GBP1,PTK7,ITGA2,MAP3K21,PTPRS,BMPR1A,SEPT5,MAPK10,RAB30,MAST1,TENM1,TNIK,MYO1D,DYRK3,BMPR2,PAK5,ATP9A,ARL15,NLRP14,ARL2,KIF5C,SELL,RASD1,P2RY1,PKN1,EPHB1,PRKCD,EHD3,RASD2,GTF2F2,SGK3,ACTA2,SGK1,PRKG2,DYNC2H1,PCK2,MYO6,SEPT3,RRAS2,SYK,FES,ATP2B1,PCSK6,PARP9,PFKFB4,TRPM4,OPLAH,RAB3B,RAB6B,RAPGEF2,NUGGC,NUAK2,AK4,MARS,AGAP2,ATP11A,GUCY1A2,PEAK1,TRIB3,FGR,RND3,FBN1,MAP2K6,GNAO1,AKT3,NEK11,PIP5KL1,KIF21A,HK1,LRRK1,BMP4,GEM,CMPK2,KIF1B,MAP3K20,ATP2B4,ABCG1,ATP1A3 GO:0005201 extracellular matrix structural constituent 0.0143273116793104 -4.24558765562683 76 14 0.00833333333333333 1680 17224 1299,10117,1285,2200,1286,3912,84034,7286,1310,1287,63827,7373,1298,85301 COL9A3,ENAM,COL4A3,FBN1,COL4A4,LAMB1,EMILIN2,TUFT1,COL19A1,COL4A5,BCAN,COL14A1,COL9A2,COL27A1 GO:0098821 BMP receptor activity 0.0147768476599485 -4.21469367038167 6 3 0.00178571428571429 1680 17224 92,657,659 ACVR2A,BMPR1A,BMPR2 GO:0035256 G-protein coupled glutamate receptor binding 0.0147768476599485 -4.21469367038167 6 3 0.00178571428571429 1680 17224 54550,9455,9454 NECAB2,HOMER2,HOMER3 GO:1990050 phosphatidic acid transporter activity 0.0147768476599485 -4.21469367038167 6 3 0.00178571428571429 1680 17224 5360,153768,27166 PLTP,PRELID2,PRELID1 GO:1904929 coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway 0.0147768476599485 -4.21469367038167 6 3 0.00178571428571429 1680 17224 4919,5754,10082 ROR1,PTK7,GPC6 GO:0005042 netrin receptor activity 0.0147768476599485 -4.21469367038167 6 3 0.00178571428571429 1680 17224 8633,219699,1630 UNC5C,UNC5B,DCC GO:0016791 phosphatase activity 0.0150819551203326 -4.19425627491672 272 38 0.0226190476190476 1680 17224 3636,1850,5789,84959,11099,64900,3628,2070,22843,8611,8555,27143,9896,5521,5791,1843,5210,5509,54961,5208,10076,5777,5783,9829,8612,1852,64077,92370,64943,5788,5795,64748,142679,8821,5799,5802,22876,5723 INPPL1,DUSP8,PTPRD,UBASH3B,PTPN21,LPIN3,INPP1,EYA4,PPM1E,PLPP1,CDC14B,PALD1,FIG4,PPP2R2B,PTPRE,DUSP1,PFKFB4,PPP1R3D,SSH3,PFKFB2,PTPRU,PTPN6,PTPN13,DNAJC6,PLPP2,DUSP9,LHPP,PXYLP1,NT5DC2,PTPRC,PTPRJ,PLPPR2,DUSP19,INPP4B,PTPRN2,PTPRS,INPP5F,PSPH GO:0015171 amino acid transmembrane transporter activity 0.0151496159264056 -4.18978009874048 84 15 0.00892857142857143 1680 17224 6541,256987,6520,6536,23657,206358,347735,8140,120103,55117,6507,6542,6510,117247,8501 SLC7A1,SERINC5,SLC3A2,SLC6A9,SLC7A11,SLC36A1,SERINC2,SLC7A5,SLC36A4,SLC6A15,SLC1A3,SLC7A2,SLC1A5,SLC16A10,SLC43A1 GO:0017124 SH3 domain binding 0.0168726140356588 -4.0820634426996 124 20 0.0119047619047619 1680 17224 5071,3636,6452,57088,51466,1793,9047,9495,5777,22941,9829,55740,1795,8631,202559,644150,84632,153090,83699,54206 PRKN,INPPL1,SH3BP2,PLSCR4,EVL,DOCK1,SH2D2A,AKAP5,PTPN6,SHANK2,DNAJC6,ENAH,DOCK3,SKAP1,KHDRBS2,WIPF3,AFAP1L2,DAB2IP,SH3BGRL2,ERRFI1 GO:0043295 glutathione binding 0.0169876925847945 -4.07526616271589 11 4 0.00238095238095238 1680 17224 2947,2946,9536,2948 GSTM3,GSTM2,PTGES,GSTM4 GO:0035259 glucocorticoid receptor binding 0.0169876925847945 -4.07526616271589 11 4 0.00238095238095238 1680 17224 4088,23426,6777,3164 SMAD3,GRIP1,STAT5B,NR4A1 GO:0005548 phospholipid transporter activity 0.0179642616832076 -4.01937095677259 56 11 0.00654761904761905 1680 17224 57088,10079,84879,10396,114879,153768,27166,23250,5360,57205,9619 PLSCR4,ATP9A,MFSD2A,ATP8A1,OSBPL5,PRELID2,PRELID1,ATP11A,PLTP,ATP10D,ABCG1 GO:0015026 coreceptor activity 0.0180663992713729 -4.01370145979169 42 9 0.00535714285714286 1680 17224 2838,7049,5754,3690,92,4040,4919,8829,10082 GPR15,TGFBR3,PTK7,ITGB3,ACVR2A,LRP6,ROR1,NRP1,GPC6 GO:0032947 protein-containing complex scaffold activity 0.0185601862556837 -3.98673651634665 86 15 0.00892857142857143 1680 17224 143098,22941,120892,9455,142679,5318,23286,23426,10399,5413,60485,80014,55964,9863,260425 MPP7,SHANK2,LRRK2,HOMER2,DUSP19,PKP2,WWC1,GRIP1,RACK1,SEPT5,SAV1,WWC2,SEPT3,MAGI2,MAGI3 GO:0099604 ligand-gated calcium channel activity 0.018989023756099 -3.96389416379435 29 7 0.00416666666666667 1680 17224 6262,22821,255231,2906,3709,56704,55283 RYR2,RASA3,MCOLN2,GRIN2D,ITPR2,JPH1,MCOLN3 GO:0050699 WW domain binding 0.018989023756099 -3.96389416379435 29 7 0.00416666666666667 1680 17224 85012,55740,10188,54602,56937,9693,9516 TCEAL3,ENAH,TNK2,NDFIP2,PMEPA1,RAPGEF2,LITAF GO:0005520 insulin-like growth factor binding 0.018989023756099 -3.96389416379435 29 7 0.00416666666666667 1680 17224 3480,3489,51232,8838,3655,3690,3486 IGF1R,IGFBP6,CRIM1,WISP3,ITGA6,ITGB3,IGFBP3 GO:0005154 epidermal growth factor receptor binding 0.018989023756099 -3.96389416379435 29 7 0.00416666666666667 1680 17224 3092,2202,10188,2241,685,10451,7039 HIP1,EFEMP1,TNK2,FER,BTC,VAV3,TGFA GO:0044212 transcription regulatory region DNA binding 0.0199531744117899 -3.91436702991879 877 104 0.0619047619047619 1680 17224 64764,29842,5071,9658,5013,2625,4869,6777,255877,1050,22807,7227,64376,8320,29841,604,5452,2115,2023,2735,7080,30818,468,4212,2649,11166,579,4774,4779,10413,100271849,467,23314,7481,474,10538,6622,53335,55509,4088,9242,81931,83439,22806,3131,60468,619279,54937,148523,688,1628,1746,63973,3219,29942,4208,64919,11279,860,4601,55893,23051,5966,122953,5324,51222,6304,4825,93986,2624,168620,4609,6720,7020,8531,2672,4091,148979,56033,1052,30062,4487,3174,2104,3164,84159,100289635,9516,9935,639,7545,1051,64324,5325,138151,26508,7494,3239,5083,26257,64754,10736,1649,3169 CREB3L2,TFCP2L1,PRKN,ZNF516,OTX1,GATA3,NPM1,STAT5B,BCL6B,CEBPA,IKZF2,TRPS1,IKZF5,EOMES,GRHL1,BCL6,POU2F2,ETV1,ENO1,GLI1,NKX2-1,KCNIP3,ATF4,MEIS2,NR6A1,SOX21,NKX3-2,NFIA,NFE2L1,YAP1,MEF2B,ATF3,SATB2,WNT11,ATOH1,BATF,SNCA,BCL11A,BATF3,SMAD3,MSC,ZNF93,TCF7L1,IKZF3,HLF,BACH2,ZNF704,SOHLH2,CIART,KLF5,DBP,DLX2,NEUROG2,HOXB9,PURG,MEF2C,BCL11B,KLF8,RUNX2,MXI1,ZNF395,ZHX3,REL,JDP2,PLAG1,ZNF219,SATB1,NKX6-1,FOXP2,GATA2,BHLHA15,MYC,SREBF1,TFAP2A,YBX3,GFI1,SMAD6,GLIS1,BARX1,CEBPD,RAX,MSX1,HNF4G,ESRRG,NR4A1,ARID5B,ZNF605,LITAF,MAFB,PRDM1,ZIC1,CEBPB,NSD1,PLAGL1,NACC2,HEYL,XBP1,HOXD13,PAX9,NKX2-8,SMYD3,SIX2,DDIT3,FOXA1 GO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific DNA binding 0.0201378816579271 -3.9051525780614 23 6 0.00357142857142857 1680 17224 4088,6875,117154,26508,4208,23462 SMAD3,TAF4B,DACH2,HEYL,MEF2C,HEY1 GO:0015278 calcium-release channel activity 0.0201378816579271 -3.9051525780614 23 6 0.00357142857142857 1680 17224 6262,22821,255231,3709,56704,55283 RYR2,RASA3,MCOLN2,ITPR2,JPH1,MCOLN3 GO:0140103 catalytic activity, acting on a glycoprotein 0.0201378816579271 -3.9051525780614 23 6 0.00357142857142857 1680 17224 90693,146664,283358,4245,11285,11282 CCDC126,MGAT5B,B4GALNT3,MGAT1,B4GALT7,MGAT4B GO:0001067 regulatory region nucleic acid binding 0.0205323567695608 -3.88575325816577 878 104 0.0619047619047619 1680 17224 64764,29842,5071,9658,5013,2625,4869,6777,255877,1050,22807,7227,64376,8320,29841,604,5452,2115,2023,2735,7080,30818,468,4212,2649,11166,579,4774,4779,10413,100271849,467,23314,7481,474,10538,6622,53335,55509,4088,9242,81931,83439,22806,3131,60468,619279,54937,148523,688,1628,1746,63973,3219,29942,4208,64919,11279,860,4601,55893,23051,5966,122953,5324,51222,6304,4825,93986,2624,168620,4609,6720,7020,8531,2672,4091,148979,56033,1052,30062,4487,3174,2104,3164,84159,100289635,9516,9935,639,7545,1051,64324,5325,138151,26508,7494,3239,5083,26257,64754,10736,1649,3169 CREB3L2,TFCP2L1,PRKN,ZNF516,OTX1,GATA3,NPM1,STAT5B,BCL6B,CEBPA,IKZF2,TRPS1,IKZF5,EOMES,GRHL1,BCL6,POU2F2,ETV1,ENO1,GLI1,NKX2-1,KCNIP3,ATF4,MEIS2,NR6A1,SOX21,NKX3-2,NFIA,NFE2L1,YAP1,MEF2B,ATF3,SATB2,WNT11,ATOH1,BATF,SNCA,BCL11A,BATF3,SMAD3,MSC,ZNF93,TCF7L1,IKZF3,HLF,BACH2,ZNF704,SOHLH2,CIART,KLF5,DBP,DLX2,NEUROG2,HOXB9,PURG,MEF2C,BCL11B,KLF8,RUNX2,MXI1,ZNF395,ZHX3,REL,JDP2,PLAG1,ZNF219,SATB1,NKX6-1,FOXP2,GATA2,BHLHA15,MYC,SREBF1,TFAP2A,YBX3,GFI1,SMAD6,GLIS1,BARX1,CEBPD,RAX,MSX1,HNF4G,ESRRG,NR4A1,ARID5B,ZNF605,LITAF,MAFB,PRDM1,ZIC1,CEBPB,NSD1,PLAGL1,NACC2,HEYL,XBP1,HOXD13,PAX9,NKX2-8,SMYD3,SIX2,DDIT3,FOXA1 GO:0051018 protein kinase A binding 0.020839833412765 -3.87088905575824 50 10 0.00595238095238095 1680 17224 84281,9465,9495,51339,120892,6262,5577,25924,131544,5569 C2orf88,AKAP7,AKAP5,DACT1,LRRK2,RYR2,PRKAR2B,MYRIP,CRYBG3,PKIA GO:0016772 transferase activity, transferring phosphorus-containing groups 0.0214190339708609 -3.84347531437913 1011 118 0.0702380952380952 1680 17224 2042,349565,685,152110,4598,90,1147,6777,4916,5596,2870,5578,780,54855,8428,1040,5891,10290,7049,6196,55603,83694,140469,92,2051,4233,5567,5159,10188,2241,91807,4139,5163,130399,5208,27133,120892,53354,5588,93,8822,4919,10110,2444,157,2260,260425,27010,8660,9149,203,5579,5754,10769,2081,84451,5603,5287,3082,657,8829,5602,22983,7301,5563,26524,23043,8444,659,57144,9748,5585,2047,2202,3480,118788,57143,5580,5592,23678,6446,5593,80216,375449,6850,2242,5210,2264,5058,123688,51232,4354,1944,81788,84033,205,55437,8476,79834,9261,57761,2268,29941,7015,57161,5608,10000,4355,3099,79858,283209,138429,1740,79705,3098,129607,51776,79646 EPHA3,NMNAT3,BTC,NEK10,MVK,ACVR1,CHUK,STAT5B,NTRK3,MAPK4,GRK6,PRKCA,DDR1,TENT5C,STK24,CDS1,MOK,SPEG,TGFBR3,RPS6KA2,TENT5A,RPS6KL1,MYO3B,ACVR2A,EPHB6,MET,PRKACB,PDGFRB,TNK2,FER,MYLK3,MARK1,PDK1,ACVR1C,PFKFB2,KCNH5,LRRK2,PANK1,PRKCQ,ACVR2B,FGF17,ROR1,SGK2,FRK,GRK3,FGFR1,MAGI3,TPK1,IRS2,DYRK1B,AK1,PRKCB,PTK7,PLK2,ERN1,MAP3K21,MAPK13,PIK3C2B,HGF,BMPR1A,NRP1,MAPK10,MAST1,TYRO3,PRKAA2,LATS2,TNIK,DYRK3,BMPR2,PAK5,SLK,PKN1,EPHB1,EFEMP1,IGF1R,PIK3AP1,ADCK1,PRKCD,PRKG1,SGK3,SGK1,PRKG2,ALPK1,MAST4,SYK,FES,PFKFB4,FGFR4,PAK1,HYKK,CRIM1,MPP1,EFNA3,NUAK2,OBSCN,AK4,STRADB,CDC42BPA,PEAK1,MAPKAPK2,TRIB3,FGR,PKN3,TERT,PELI2,MAP2K6,AKT3,MPP2,HK2,NEK11,PGM2L1,PIP5KL1,DLG2,LRRK1,HK1,CMPK2,MAP3K20,PANK3 GO:0035639 purine ribonucleoside triphosphate binding 0.021830280664983 -3.82445725165534 1796 200 0.119047619047619 1680 17224 349565,4598,2180,90,3798,10396,51175,445,5578,5881,16,8428,10382,5891,8153,6196,1768,5911,25837,54805,2051,5567,5159,51062,10188,4139,10257,130399,120892,1244,93,4919,10110,157,2770,9149,203,5167,10769,540,2081,5603,148252,5287,144132,58528,5563,833,7301,26524,860,9886,6334,9748,284716,65997,122622,26038,116835,1938,3480,57143,23461,5592,112,80216,55137,375449,5058,2264,23433,4651,11001,55437,84033,8476,55760,9261,57494,29941,11031,3099,162394,79646,387751,6296,92170,2042,26052,152110,29984,4430,5596,4916,1147,2870,23046,780,91351,10290,440,83694,140469,92,22989,5874,4233,379,1767,3306,2241,91807,2617,7846,5163,5208,4597,53354,107,5588,481,23682,2444,79739,57205,260425,2260,7453,27010,953,5579,2633,5754,84451,657,5413,5602,27314,22983,23043,4642,8444,659,57144,10079,54622,338323,402,3800,51655,5028,5585,2047,5580,30845,23551,2963,23678,59,6446,5593,79659,5106,4646,55964,22800,6850,2242,490,5210,54795,26873,5865,51560,389643,81788,205,4141,116986,23250,2977,79834,57761,2268,390,5608,2775,10000,79858,138429,55605,3098,79705,2669,129607,23095,51776,493,9619,478 NMNAT3,MVK,ACSL1,ACVR1,KIF5A,ATP8A1,TUBE1,ASS1,PRKCA,RAC3,AARS,STK24,TUBB4A,MOK,RND2,RPS6KA2,DNAH6,RAP2A,RAB26,CNNM2,EPHB6,PRKACB,PDGFRB,ATL1,TNK2,MARK1,ABCC4,ACVR1C,LRRK2,ABCC2,ACVR2B,ROR1,SGK2,GRK3,GNAI1,DYRK1B,AK1,ENPP1,PLK2,ATP7B,ERN1,MAPK13,DIRAS1,PIK3C2B,DNHD1,RRAGD,PRKAA2,CARS,TYRO3,LATS2,RUNX2,RHOBTB1,SCN8A,SLK,RIMKLA,RASL11B,ADSSL1,CHD5,HSPA12B,EEF2,IGF1R,ADCK1,ABCA5,PRKG1,ADCY6,ALPK1,FIGN,MAST4,PAK1,FGFR4,RHOQ,MYO10,SLC27A2,STRADB,OBSCN,CDC42BPA,DHX32,MAPKAPK2,RIMKLB,PKN3,RAB31,HK2,SLFN5,PANK3,GVINP1,ACSM3,MTG1,EPHA3,DNM3,NEK10,RHOD,MYO1B,MAPK4,NTRK3,CHUK,GRK6,KIF21B,DDR1,DDX60L,SPEG,ASNS,RPS6KL1,MYO3B,ACVR2A,MYH15,RAB27B,MET,ARL4D,DNAH5,HSPA2,FER,MYLK3,GARS,TUBA1A,PDK1,PFKFB2,MVD,PANK1,ADCY1,PRKCQ,ATP1B1,RAB38,FRK,TTLL7,ATP10D,MAGI3,FGFR1,WARS,TPK1,ENTPD1,PRKCB,GBP1,PTK7,MAP3K21,BMPR1A,SEPT5,MAPK10,RAB30,MAST1,TNIK,MYO1D,DYRK3,BMPR2,PAK5,ATP9A,ARL15,NLRP14,ARL2,KIF5C,RASD1,P2RY1,PKN1,EPHB1,PRKCD,EHD3,RASD2,GTF2F2,SGK3,ACTA2,SGK1,PRKG2,DYNC2H1,PCK2,MYO6,SEPT3,RRAS2,SYK,FES,ATP2B1,PFKFB4,TRPM4,OPLAH,RAB3B,RAB6B,NUGGC,NUAK2,AK4,MARS,AGAP2,ATP11A,GUCY1A2,PEAK1,TRIB3,FGR,RND3,MAP2K6,GNAO1,AKT3,NEK11,PIP5KL1,KIF21A,HK1,LRRK1,GEM,CMPK2,KIF1B,MAP3K20,ATP2B4,ABCG1,ATP1A3 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding 0.0220410156173381 -3.81485021511763 236 33 0.0196428571428571 1680 17224 11279,4601,122953,2625,255877,51222,6304,7227,4825,93986,64376,604,7020,8531,2672,2023,148979,6591,4487,30818,579,84159,467,639,23414,55509,53335,1051,9242,60468,138151,26137,29942 KLF8,MXI1,JDP2,GATA3,BCL6B,ZNF219,SATB1,TRPS1,NKX6-1,FOXP2,IKZF5,BCL6,TFAP2A,YBX3,GFI1,ENO1,GLIS1,SNAI2,MSX1,KCNIP3,NKX3-2,ARID5B,ATF3,PRDM1,ZFPM2,BATF3,BCL11A,CEBPB,MSC,BACH2,NACC2,ZBTB20,PURG GO:0051015 actin filament binding 0.0224781957677621 -3.7952095166188 177 26 0.0154761904761905 1680 17224 4642,4651,11034,4430,3092,119,5357,122622,55607,1496,5358,85477,2934,3983,1938,644150,783,79983,6840,9172,22989,4082,7168,83660,4646,57698 MYO1D,MYO10,DSTN,MYO1B,HIP1,ADD2,PLS1,ADSSL1,PPP1R9A,CTNNA2,PLS3,SCIN,GSN,ABLIM1,EEF2,WIPF3,CACNB2,POF1B,SVIL,MYOM2,MYH15,MARCKS,TPM1,TLN2,MYO6,SHTN1 GO:0004185 serine-type carboxypeptidase activity 0.0235483163120156 -3.74870095525747 12 4 0.00238095238095238 1680 17224 119587,54504,1363,5547 CPXM2,CPVL,CPE,PRCP GO:0019992 diacylglycerol binding 0.0235483163120156 -3.74870095525747 12 4 0.00238095238095238 1680 17224 10497,5360,9693,10125 UNC13B,PLTP,RAPGEF2,RASGRP1 GO:1900750 oligopeptide binding 0.0235483163120156 -3.74870095525747 12 4 0.00238095238095238 1680 17224 2947,2946,9536,2948 GSTM3,GSTM2,PTGES,GSTM4 GO:0048185 activin binding 0.0235483163120156 -3.74870095525747 12 4 0.00238095238095238 1680 17224 92,93,90,7049 ACVR2A,ACVR2B,ACVR1,TGFBR3 GO:0016846 carbon-sulfur lyase activity 0.0235483163120156 -3.74870095525747 12 4 0.00238095238095238 1680 17224 241,4259,201161,1491 ALOX5AP,MGST3,CENPV,CTH GO:0043169 cation binding 0.0237138012762534 -3.74169806799936 4185 442 0.263095238095238 1680 17224 8448,23077,161823,90,5153,10396,3949,2625,11174,5578,767,16,2070,23413,8428,5099,7227,6497,54749,5891,64376,57732,5911,11262,1363,5360,2731,4093,130399,2649,253827,114327,3752,93,2161,377677,2770,5167,10781,57630,147372,57089,540,649,26137,2073,8829,50859,4026,833,26524,11279,9620,23051,1573,3655,219749,6507,122622,51440,26038,79056,2122,1123,3983,26301,6307,200558,85416,119587,10960,93664,84171,26002,85460,375449,148979,1131,9699,25946,220441,54885,7436,8642,80258,100289635,2274,6262,7468,5357,715,79740,8476,23236,10150,148156,64506,4324,747,57494,9508,7060,54814,4147,1015,1000,64754,270,1466,6296,5321,170685,9658,9781,79695,11226,282890,9378,780,83594,9372,57484,152485,4753,1138,220929,5144,64219,22891,4661,55184,64168,153830,107,5588,481,26108,444,57205,114991,254042,3669,6622,252884,7552,3363,22806,27295,5579,27018,6999,90874,619279,5066,57333,5033,688,657,4306,4281,57088,10079,5324,875,2621,9586,51222,3628,85301,80853,4245,23467,23158,2672,4091,678,10924,9331,54795,9260,10451,5829,116984,64283,171425,777,9693,22821,23250,148206,7545,57493,2591,643836,64324,56129,5352,7015,2775,7703,283209,79858,79705,11285,493,7178,200035,1911,478,7093,23321,10626,91683,29995,3512,3709,146664,18,255928,22807,92737,83872,56884,5358,1595,10382,113622,11328,285180,22843,6196,744,25924,374378,2023,9353,5567,10125,346157,1545,3695,10188,30818,4139,83667,23670,475,284161,147929,22838,27244,64943,2009,114088,2934,11278,8974,2081,123036,64919,5563,91694,55034,55893,9871,219654,284716,388403,285440,7762,7546,114805,6319,22856,56122,50862,2202,285671,2589,253461,56952,760,6940,590,126070,2624,80144,10846,57593,112,22998,378925,4846,23361,337876,57575,60437,11043,3048,81790,11282,6920,80267,84033,5151,64409,639,64077,26872,144193,5325,2195,51162,79845,54997,4311,5071,57643,152110,1951,54947,79710,80781,55769,11237,255877,144811,821,27445,1592,221833,79149,85477,10247,149076,3422,10497,83852,118987,26468,604,25925,92,55240,5627,118738,10794,93349,6591,2735,3486,25801,118429,1447,59336,26136,48,54941,8973,79825,148266,53335,4088,5903,81931,89782,53840,154214,3673,199990,55819,113612,55762,5723,22983,23324,54510,8444,54550,2026,659,1047,4038,55784,64084,6402,56978,3046,79008,58495,5523,93986,1124,121355,5580,30845,1829,10612,115123,166336,687,5106,8792,55033,490,92597,9645,9099,10765,3174,2104,3164,1397,9516,55616,81788,55753,144165,5638,116986,23414,9941,79623,4255,27293,473,1879,170691,23576,79633,91133,2200,7761,133923,388558,2669,56906,114804,51776,4325,781,9310 DOC2A,MYCBP2,ADAL,ACVR1,PDE1B,ATP8A1,LDLR,GATA3,ADAMTS6,PRKCA,CA8,AARS,EYA4,NCS1,STK24,PCDH7,TRPS1,SKI,EPDR1,MOK,IKZF5,ZFYVE28,RAP2A,SP140,CPE,PLTP,GLDC,SMAD9,ACVR1C,NR6A1,MSRB3,EFHC1,KCND3,ACVR2B,F12,CA13,GNAI1,ENPP1,ZNF266,SH3RF1,CCBE1,ENTPD7,ATP7B,BMP1,ZBTB20,ERCC5,NRP1,SPOCK3,LPP,CARS,LATS2,KLF8,CELSR1,ZHX3,CYP2J2,ITGA6,ZNF25,SLC1A3,ADSSL1,HPCAL4,CHD5,PRRG4,MECOM,CHN1,ABLIM1,GBGT1,MSMO1,APLF,ZIC5,CPXM2,LMAN2,CADPS2,LOXL4,MOXD1,ZNF518B,MAST4,GLIS1,CHRM3,RIMS2,ZNF385A,RNF152,TBC1D8B,VLDLR,DCHS1,EFHC2,ZNF605,FHL2,RYR2,NSD2,PLS1,C1R,ZBBX,CDC42BPA,PLCB1,MBNL2,ZNF558,CPEB1,MMP15,DAGLA,RIMKLB,ADAMTS3,THBS4,QPCTL,MATN2,CDH17,CDH2,SMYD3,AMPD1,CSRP2,ACSM3,PLA2G4A,NUDT10,ZNF516,RNF144A,GALNT12,GALNT6,ZNF311,NRXN1,DDR1,NUDT12,ZFYVE9,RNF150,ZNF827,NELL2,CHRNA5,ZNF438,PDE4D,PJA1,ZNF365,MYT1,DZANK1,NECAB1,RNF145,ADCY1,PRKCQ,ATP1B1,PYGO1,ASPH,ATP10D,ZNF618,METAP1D,ISG20,SNCA,ZNF396,ZNF711,HTR7,IKZF3,PDLIM3,PRKCB,BEX3,TDO2,ZNF697,ZNF704,PAM,RCN3,P4HA1,KLF5,BMPR1A,NR3C2,MID1,PLSCR4,ATP9A,PLAG1,CBS,GAS6,CREB5,ZNF219,INPP1,COL27A1,KDM7A,MGAT1,NPTXR,TBC1D9,GFI1,SMAD6,ZFP36L2,SMPDL3A,B4GALT6,TRPM4,PDLIM7,VAV3,PXN,ARAP2,ARHGEF28,CLYBL,CACNA1E,RAPGEF2,RASA3,ATP11A,ZNF714,ZIC1,HEG1,GALNT3,ZFP62,NSD1,PCDHB7,PLOD2,TERT,GNAO1,PCGF2,PGM2L1,NEK11,LRRK1,B4GALT7,ATP2B4,TPT1,NUDT17,PHC1,ATP1A3,TLL2,TRIM2,TRIM16,SYT12,LMCD1,JCHAIN,ITPR2,MGAT5B,ABAT,SYT14,IKZF2,DNER,HMCN1,FSTL5,PLS3,CYP51A1,TUBB4A,ADPRHL1,FKBP9,RUFY4,PPM1E,RPS6KA2,MPPED2,MYRIP,GALNT18,ENO1,SLIT2,PRKACB,RASGRP1,ZNF391,CYP1B1,ITGB7,TNK2,KCNIP3,MARK1,SESN2,CEMIP2,ATOX1,GDPD1,ZNF565,RNF44,SESN1,NT5DC2,EML1,TRIM9,GSN,KLF12,P4HA2,ERN1,TC2N,BCL11B,PRKAA2,LONRF1,MOCOS,ZNF395,SEC24D,ZCCHC24,RIMKLA,YPEL2,CYP4V2,ZNF215,ZIC2,GALNT13,SCD,CHSY1,PCDHB14,RNF141,EFEMP1,RNF180,GALNT1,ZBTB38,PRTFDC1,CA2,ZNF354A,BCHE,ZNF440,GATA2,FRAS1,PDE10A,EBF4,ADCY6,LIMCH1,RNF148,NOS3,ZNF629,CHSY3,PCDH10,CDH26,MID2,HBG2,RNF170,MGAT4B,TCEA3,EDEM3,OBSCN,PDE8A,GALNT17,PRDM1,LHPP,STEAP1,AMDHD1,PLAGL1,FAT1,EGFL7,RNF122,TESC,MME,PRKN,ZSWIM5,NEK10,CELSR3,LPCAT2,MORC4,COL18A1,ZNF83,RNF24,BCL6B,LACC1,CANX,PCLO,CYP26A1,SP8,ZSCAN5A,SCIN,RIDA,ZNF362,IDI1,UNC13B,SETDB2,PDZD8,LHX6,BCL6,ZNF521,ACVR2A,STEAP3,PROS1,ZNF488,ZNF460,SP140L,SNAI2,GLI1,IGFBP3,GCA,ANTXR2,CSN2,PRDM13,TES,ACO1,RNF125,CHRNA6,EFCC1,ZNF569,BCL11A,SMAD3,RANBP2,ZNF93,LMLN,TRIM34,RNF217,ITGA2,FAAP20,RNF130,CYP2U1,ZNF701,PSPH,MAST1,MAN2B2,PCDH18,DYRK3,NECAB2,ENO2,BMPR2,CLGN,LRP4,MCTP2,CLSTN2,SELL,PRDM8,HBE1,SLX1B,OVOL2,PPP2R3A,FOXP2,CHN2,GTSF1,PRKCD,EHD3,DSG2,TRIM3,MARCH3,PRICKLE2,KLF9,PCK2,TNFRSF11A,FKBP14,ATP2B1,MOB1B,MICAL2,USP2,KDM5B,HNF4G,ESRRG,NR4A1,CRIP2,LITAF,ASAP3,NUAK2,OGDHL,PRICKLE1,PRRG1,AGAP2,ZFPM2,EXOG,GALNT14,MGMT,SMPDL3B,RERE,EBF1,ADAMTS17,DDAH1,FAT4,L3MBTL4,FBN1,ZNF214,ZNF474,ZNF808,GEM,THAP10,RNF157,MAP3K20,MMP16,CACNA2D1,ZNF235 GO:0005246 calcium channel regulator activity 0.0238901897311249 -3.73428737581221 37 8 0.00476190476190476 1680 17224 6446,27075,10110,9378,51440,23678,29763,5592 SGK1,TSPAN13,SGK2,NRXN1,HPCAL4,SGK3,PACSIN3,PRKG1 GO:0035529 NADH pyrophosphatase activity 0.0240008232800166 -3.72966714588851 7 3 0.00178571428571429 1680 17224 5167,83594,200035 ENPP1,NUDT12,NUDT17 GO:0102756 very-long-chain 3-ketoacyl-CoA synthase activity 0.0240008232800166 -3.72966714588851 7 3 0.00178571428571429 1680 17224 6785,79993,83401 ELOVL4,ELOVL7,ELOVL3 GO:0016842 amidine-lyase activity 0.0240008232800166 -3.72966714588851 7 3 0.00178571428571429 1680 17224 79094,87769,5066 CHAC1,GGACT,PAM GO:0035184 histone threonine kinase activity 0.0240008232800166 -3.72966714588851 7 3 0.00178571428571429 1680 17224 5578,5585,5579 PRKCA,PKN1,PRKCB GO:0102337 3-oxo-cerotoyl-CoA synthase activity 0.0240008232800166 -3.72966714588851 7 3 0.00178571428571429 1680 17224 6785,79993,83401 ELOVL4,ELOVL7,ELOVL3 GO:0102338 3-oxo-lignoceronyl-CoA synthase activity 0.0240008232800166 -3.72966714588851 7 3 0.00178571428571429 1680 17224 6785,79993,83401 ELOVL4,ELOVL7,ELOVL3 GO:0009922 fatty acid elongase activity 0.0240008232800166 -3.72966714588851 7 3 0.00178571428571429 1680 17224 6785,79993,83401 ELOVL4,ELOVL7,ELOVL3 GO:0102336 3-oxo-arachidoyl-CoA synthase activity 0.0240008232800166 -3.72966714588851 7 3 0.00178571428571429 1680 17224 6785,79993,83401 ELOVL4,ELOVL7,ELOVL3 GO:0032561 guanyl ribonucleotide binding 0.0240705147306821 -3.72676764267621 387 50 0.0297619047619048 1680 17224 92170,26052,9886,29984,54622,402,51175,65997,51655,122622,5881,10382,8153,1938,10846,5911,23551,30845,25837,5592,5593,5106,379,5874,55964,22800,51062,5865,23433,7846,51560,9693,389643,120892,205,116986,23682,2977,2770,390,2633,2775,11031,148252,79705,2669,5413,27314,387751,58528 MTG1,DNM3,RHOBTB1,RHOD,ARL15,ARL2,TUBE1,RASL11B,RASD1,ADSSL1,RAC3,TUBB4A,RND2,EEF2,PDE10A,RAP2A,RASD2,EHD3,RAB26,PRKG1,PRKG2,PCK2,ARL4D,RAB27B,SEPT3,RRAS2,ATL1,RAB3B,RHOQ,TUBA1A,RAB6B,RAPGEF2,NUGGC,LRRK2,AK4,AGAP2,RAB38,GUCY1A2,GNAI1,RND3,GBP1,GNAO1,RAB31,DIRAS1,LRRK1,GEM,SEPT5,RAB30,GVINP1,RRAGD GO:0004709 MAP kinase kinase kinase activity 0.0241291642704274 -3.72433403440717 81 14 0.00833333333333333 1680 17224 2042,2264,7301,3480,84451,4916,4919,2051,4233,2047,780,51776,2260,5159 EPHA3,FGFR4,TYRO3,IGF1R,MAP3K21,NTRK3,ROR1,EPHB6,MET,EPHB1,DDR1,MAP3K20,FGFR1,PDGFRB GO:0050662 coenzyme binding 0.0241332627057509 -3.72416419482014 281 38 0.0226190476190476 1680 17224 84706,55034,23464,1718,7358,875,1488,18,26227,114112,7881,8435,51166,8564,85007,83666,4846,2731,3156,1491,9645,2597,217,51700,2194,55753,197257,64850,5352,2329,8974,56898,5066,5033,6713,3248,1717,51084 GPT2,MOCOS,GCAT,DHCR24,UGDH,CBS,CTBP2,ABAT,PHGDH,TXNRD3,KCNAB1,SOAT2,AADAT,KMO,PHYKPL,PARP9,NOS3,GLDC,HMGCR,CTH,MICAL2,GAPDH,ALDH2,CYB5R2,FASN,OGDHL,LDHD,ETNPPL,PLOD2,FMO4,P4HA2,BDH2,PAM,P4HA1,SQLE,HPGD,DHCR7,CRYL1 GO:0005031 tumor necrosis factor-activated receptor activity 0.0246934833852656 -3.70121590071366 24 6 0.00357142857142857 1680 17224 8794,958,60401,55504,8792,7132 TNFRSF10C,CD40,EDA2R,TNFRSF19,TNFRSF11A,TNFRSF1A GO:0005035 death receptor activity 0.0246934833852656 -3.70121590071366 24 6 0.00357142857142857 1680 17224 8794,958,60401,55504,8792,7132 TNFRSF10C,CD40,EDA2R,TNFRSF19,TNFRSF11A,TNFRSF1A GO:0019001 guanyl nucleotide binding 0.0251021488305935 -3.68480182572818 388 50 0.0297619047619048 1680 17224 92170,26052,9886,29984,54622,402,51175,65997,51655,122622,5881,10382,8153,1938,10846,5911,23551,30845,25837,5592,5593,5106,379,5874,55964,22800,51062,5865,23433,7846,51560,9693,389643,120892,205,116986,23682,2977,2770,390,2633,2775,11031,148252,79705,2669,5413,27314,387751,58528 MTG1,DNM3,RHOBTB1,RHOD,ARL15,ARL2,TUBE1,RASL11B,RASD1,ADSSL1,RAC3,TUBB4A,RND2,EEF2,PDE10A,RAP2A,RASD2,EHD3,RAB26,PRKG1,PRKG2,PCK2,ARL4D,RAB27B,SEPT3,RRAS2,ATL1,RAB3B,RHOQ,TUBA1A,RAB6B,RAPGEF2,NUGGC,LRRK2,AK4,AGAP2,RAB38,GUCY1A2,GNAI1,RND3,GBP1,GNAO1,RAB31,DIRAS1,LRRK1,GEM,SEPT5,RAB30,GVINP1,RRAGD GO:0046872 metal ion binding 0.0253506947944108 -3.674949141257 4090 432 0.257142857142857 1680 17224 8448,23077,161823,90,5153,10396,3949,2625,11174,5578,767,16,2070,8428,23413,5099,7227,6497,54749,5891,64376,57732,5911,11262,1363,4093,130399,2649,253827,114327,3752,93,2161,377677,2770,5167,10781,57630,147372,57089,540,649,26137,2073,8829,50859,4026,833,26524,11279,9620,23051,1573,3655,219749,6507,122622,51440,26038,79056,2122,1123,3983,26301,6307,200558,85416,119587,10960,93664,84171,26002,85460,375449,148979,9699,25946,220441,54885,7436,8642,80258,100289635,2274,6262,7468,5357,715,79740,8476,23236,10150,148156,64506,4324,747,57494,9508,7060,54814,4147,1015,1000,64754,270,1466,6296,5321,170685,9658,9781,79695,11226,282890,9378,780,83594,9372,57484,152485,4753,220929,5144,64219,22891,4661,55184,64168,153830,107,5588,481,26108,444,57205,114991,254042,3669,6622,252884,7552,22806,27295,5579,27018,6999,90874,619279,5066,57333,5033,688,657,4306,4281,57088,10079,5324,875,2621,9586,51222,3628,85301,80853,4245,23467,23158,2672,4091,678,10924,9331,9260,54795,10451,5829,116984,64283,171425,777,9693,22821,23250,148206,7545,57493,2591,643836,64324,56129,5352,7015,2775,7703,283209,79858,79705,11285,493,7178,200035,1911,478,7093,23321,10626,91683,29995,3709,146664,18,255928,22807,92737,83872,56884,5358,1595,10382,113622,11328,285180,22843,6196,744,25924,374378,2023,9353,5567,10125,346157,1545,3695,10188,30818,4139,23670,475,284161,147929,22838,64943,2009,114088,2934,11278,8974,2081,123036,64919,5563,91694,55034,55893,9871,219654,284716,388403,285440,7762,7546,114805,6319,22856,56122,50862,2202,285671,2589,253461,56952,760,6940,126070,2624,80144,10846,57593,112,22998,378925,4846,23361,337876,57575,60437,11043,3048,81790,11282,6920,80267,84033,5151,64409,639,64077,26872,144193,5325,2195,51162,79845,54997,4311,5071,152110,57643,1951,54947,79710,80781,55769,11237,255877,144811,821,27445,1592,221833,79149,85477,10247,149076,3422,10497,83852,118987,26468,604,25925,92,55240,5627,118738,10794,93349,6591,2735,3486,25801,118429,1447,59336,26136,48,54941,79825,148266,53335,4088,5903,81931,89782,53840,154214,3673,199990,55819,113612,55762,5723,22983,23324,54510,8444,54550,2026,659,1047,4038,55784,64084,6402,56978,3046,79008,58495,5523,93986,1124,121355,5580,30845,1829,10612,115123,166336,687,5106,8792,55033,490,92597,9645,9099,10765,3174,2104,3164,1397,9516,55616,81788,55753,144165,5638,116986,23414,9941,79623,4255,27293,473,1879,170691,23576,79633,91133,2200,7761,133923,388558,2669,56906,114804,51776,4325,781,9310 DOC2A,MYCBP2,ADAL,ACVR1,PDE1B,ATP8A1,LDLR,GATA3,ADAMTS6,PRKCA,CA8,AARS,EYA4,STK24,NCS1,PCDH7,TRPS1,SKI,EPDR1,MOK,IKZF5,ZFYVE28,RAP2A,SP140,CPE,SMAD9,ACVR1C,NR6A1,MSRB3,EFHC1,KCND3,ACVR2B,F12,CA13,GNAI1,ENPP1,ZNF266,SH3RF1,CCBE1,ENTPD7,ATP7B,BMP1,ZBTB20,ERCC5,NRP1,SPOCK3,LPP,CARS,LATS2,KLF8,CELSR1,ZHX3,CYP2J2,ITGA6,ZNF25,SLC1A3,ADSSL1,HPCAL4,CHD5,PRRG4,MECOM,CHN1,ABLIM1,GBGT1,MSMO1,APLF,ZIC5,CPXM2,LMAN2,CADPS2,LOXL4,MOXD1,ZNF518B,MAST4,GLIS1,RIMS2,ZNF385A,RNF152,TBC1D8B,VLDLR,DCHS1,EFHC2,ZNF605,FHL2,RYR2,NSD2,PLS1,C1R,ZBBX,CDC42BPA,PLCB1,MBNL2,ZNF558,CPEB1,MMP15,DAGLA,RIMKLB,ADAMTS3,THBS4,QPCTL,MATN2,CDH17,CDH2,SMYD3,AMPD1,CSRP2,ACSM3,PLA2G4A,NUDT10,ZNF516,RNF144A,GALNT12,GALNT6,ZNF311,NRXN1,DDR1,NUDT12,ZFYVE9,RNF150,ZNF827,NELL2,ZNF438,PDE4D,PJA1,ZNF365,MYT1,DZANK1,NECAB1,RNF145,ADCY1,PRKCQ,ATP1B1,PYGO1,ASPH,ATP10D,ZNF618,METAP1D,ISG20,SNCA,ZNF396,ZNF711,IKZF3,PDLIM3,PRKCB,BEX3,TDO2,ZNF697,ZNF704,PAM,RCN3,P4HA1,KLF5,BMPR1A,NR3C2,MID1,PLSCR4,ATP9A,PLAG1,CBS,GAS6,CREB5,ZNF219,INPP1,COL27A1,KDM7A,MGAT1,NPTXR,TBC1D9,GFI1,SMAD6,ZFP36L2,SMPDL3A,B4GALT6,PDLIM7,TRPM4,VAV3,PXN,ARAP2,ARHGEF28,CLYBL,CACNA1E,RAPGEF2,RASA3,ATP11A,ZNF714,ZIC1,HEG1,GALNT3,ZFP62,NSD1,PCDHB7,PLOD2,TERT,GNAO1,PCGF2,PGM2L1,NEK11,LRRK1,B4GALT7,ATP2B4,TPT1,NUDT17,PHC1,ATP1A3,TLL2,TRIM2,TRIM16,SYT12,LMCD1,ITPR2,MGAT5B,ABAT,SYT14,IKZF2,DNER,HMCN1,FSTL5,PLS3,CYP51A1,TUBB4A,ADPRHL1,FKBP9,RUFY4,PPM1E,RPS6KA2,MPPED2,MYRIP,GALNT18,ENO1,SLIT2,PRKACB,RASGRP1,ZNF391,CYP1B1,ITGB7,TNK2,KCNIP3,MARK1,CEMIP2,ATOX1,GDPD1,ZNF565,RNF44,NT5DC2,EML1,TRIM9,GSN,KLF12,P4HA2,ERN1,TC2N,BCL11B,PRKAA2,LONRF1,MOCOS,ZNF395,SEC24D,ZCCHC24,RIMKLA,YPEL2,CYP4V2,ZNF215,ZIC2,GALNT13,SCD,CHSY1,PCDHB14,RNF141,EFEMP1,RNF180,GALNT1,ZBTB38,PRTFDC1,CA2,ZNF354A,ZNF440,GATA2,FRAS1,PDE10A,EBF4,ADCY6,LIMCH1,RNF148,NOS3,ZNF629,CHSY3,PCDH10,CDH26,MID2,HBG2,RNF170,MGAT4B,TCEA3,EDEM3,OBSCN,PDE8A,GALNT17,PRDM1,LHPP,STEAP1,AMDHD1,PLAGL1,FAT1,EGFL7,RNF122,TESC,MME,PRKN,NEK10,ZSWIM5,CELSR3,LPCAT2,MORC4,COL18A1,ZNF83,RNF24,BCL6B,LACC1,CANX,PCLO,CYP26A1,SP8,ZSCAN5A,SCIN,RIDA,ZNF362,IDI1,UNC13B,SETDB2,PDZD8,LHX6,BCL6,ZNF521,ACVR2A,STEAP3,PROS1,ZNF488,ZNF460,SP140L,SNAI2,GLI1,IGFBP3,GCA,ANTXR2,CSN2,PRDM13,TES,ACO1,RNF125,EFCC1,ZNF569,BCL11A,SMAD3,RANBP2,ZNF93,LMLN,TRIM34,RNF217,ITGA2,FAAP20,RNF130,CYP2U1,ZNF701,PSPH,MAST1,MAN2B2,PCDH18,DYRK3,NECAB2,ENO2,BMPR2,CLGN,LRP4,MCTP2,CLSTN2,SELL,PRDM8,HBE1,SLX1B,OVOL2,PPP2R3A,FOXP2,CHN2,GTSF1,PRKCD,EHD3,DSG2,TRIM3,MARCH3,PRICKLE2,KLF9,PCK2,TNFRSF11A,FKBP14,ATP2B1,MOB1B,MICAL2,USP2,KDM5B,HNF4G,ESRRG,NR4A1,CRIP2,LITAF,ASAP3,NUAK2,OGDHL,PRICKLE1,PRRG1,AGAP2,ZFPM2,EXOG,GALNT14,MGMT,SMPDL3B,RERE,EBF1,ADAMTS17,DDAH1,FAT4,L3MBTL4,FBN1,ZNF214,ZNF474,ZNF808,GEM,THAP10,RNF157,MAP3K20,MMP16,CACNA2D1,ZNF235 GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor 0.0255274769401263 -3.66799987986958 18 5 0.00297619047619048 1680 17224 10157,160428,645,10840,5831 AASS,ALDH1L2,BLVRB,ALDH1L1,PYCR1 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed 0.0255274769401263 -3.66799987986958 18 5 0.00297619047619048 1680 17224 79659,144132,1768,1767,51626 DYNC2H1,DNHD1,DNAH6,DNAH5,DYNC2LI1 GO:0003924 GTPase activity 0.0256631744289868 -3.66269821626203 291 39 0.0232142857142857 1680 17224 92170,26052,9886,29984,402,51175,65997,51655,122622,5881,8153,10382,1938,23551,5911,25837,379,5874,22800,55964,51062,5865,23433,7846,51560,389643,120892,116986,23682,2770,390,2775,2633,11031,148252,2669,5413,27314,58528 MTG1,DNM3,RHOBTB1,RHOD,ARL2,TUBE1,RASL11B,RASD1,ADSSL1,RAC3,RND2,TUBB4A,EEF2,RASD2,RAP2A,RAB26,ARL4D,RAB27B,RRAS2,SEPT3,ATL1,RAB3B,RHOQ,TUBA1A,RAB6B,NUGGC,LRRK2,AGAP2,RAB38,GNAI1,RND3,GNAO1,GBP1,RAB31,DIRAS1,GEM,SEPT5,RAB30,RRAGD GO:0003690 double-stranded DNA binding 0.026518562379296 -3.62991032405932 859 101 0.0601190476190476 1680 17224 64764,29842,5071,9658,5013,2625,6777,255877,1050,7227,64376,8320,29841,604,5452,2115,2023,2735,7080,30818,468,4212,2649,11166,579,4774,4779,10413,100271849,467,23314,474,10538,53335,55509,4088,9242,81931,22806,3131,60468,619279,54937,148523,688,2073,1628,1746,63973,3219,29942,4208,23462,64919,11279,860,4601,55893,23051,5966,122953,5324,51222,6304,4825,93986,2624,2334,168620,4609,6720,7020,8531,4091,148979,56033,1052,30062,4487,10765,3174,2104,3164,84159,100289635,9516,9935,639,7545,1051,64324,5325,138151,26508,7494,3239,5083,26257,64754,10736,1649 CREB3L2,TFCP2L1,PRKN,ZNF516,OTX1,GATA3,STAT5B,BCL6B,CEBPA,TRPS1,IKZF5,EOMES,GRHL1,BCL6,POU2F2,ETV1,ENO1,GLI1,NKX2-1,KCNIP3,ATF4,MEIS2,NR6A1,SOX21,NKX3-2,NFIA,NFE2L1,YAP1,MEF2B,ATF3,SATB2,ATOH1,BATF,BCL11A,BATF3,SMAD3,MSC,ZNF93,IKZF3,HLF,BACH2,ZNF704,SOHLH2,CIART,KLF5,ERCC5,DBP,DLX2,NEUROG2,HOXB9,PURG,MEF2C,HEY1,BCL11B,KLF8,RUNX2,MXI1,ZNF395,ZHX3,REL,JDP2,PLAG1,ZNF219,SATB1,NKX6-1,FOXP2,GATA2,AFF2,BHLHA15,MYC,SREBF1,TFAP2A,YBX3,SMAD6,GLIS1,BARX1,CEBPD,RAX,MSX1,KDM5B,HNF4G,ESRRG,NR4A1,ARID5B,ZNF605,LITAF,MAFB,PRDM1,ZIC1,CEBPB,NSD1,PLAGL1,NACC2,HEYL,XBP1,HOXD13,PAX9,NKX2-8,SMYD3,SIX2,DDIT3 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity 0.0266729230493309 -3.6241063461441 3 2 0.00119047619047619 1680 17224 90693,146664 CCDC126,MGAT5B GO:0030614 oxidoreductase activity, acting on phosphorus or arsenic in donors, disulfide as acceptor 0.0266729230493309 -3.6241063461441 3 2 0.00119047619047619 1680 17224 9446,119391 GSTO1,GSTO2 GO:0015173 aromatic amino acid transmembrane transporter activity 0.0266729230493309 -3.6241063461441 3 2 0.00119047619047619 1680 17224 120103,117247 SLC36A4,SLC16A10 GO:0008158 hedgehog receptor activity 0.0266729230493309 -3.6241063461441 3 2 0.00119047619047619 1680 17224 8643,27077 PTCH2,B9D1 GO:0015275 stretch-activated, cation-selective, calcium channel activity 0.0266729230493309 -3.6241063461441 3 2 0.00119047619047619 1680 17224 27112,728215 FAM155B,FAM155A GO:0035939 microsatellite binding 0.0266729230493309 -3.6241063461441 3 2 0.00119047619047619 1680 17224 26508,23462 HEYL,HEY1 GO:0016672 oxidoreductase activity, acting on a sulfur group of donors, quinone or similar compound as acceptor 0.0266729230493309 -3.6241063461441 3 2 0.00119047619047619 1680 17224 9446,119391 GSTO1,GSTO2 GO:0030613 oxidoreductase activity, acting on phosphorus or arsenic in donors 0.0266729230493309 -3.6241063461441 3 2 0.00119047619047619 1680 17224 9446,119391 GSTO1,GSTO2 GO:0004332 fructose-bisphosphate aldolase activity 0.0266729230493309 -3.6241063461441 3 2 0.00119047619047619 1680 17224 230,226 ALDOC,ALDOA GO:0017147 Wnt-protein binding 0.0269747606442591 -3.61285364112071 31 7 0.00416666666666667 1680 17224 4040,4919,8322,8325,79971,4038,8321 LRP6,ROR1,FZD4,FZD8,WLS,LRP4,FZD1 GO:0005272 sodium channel activity 0.0276105094467823 -3.58955880167889 45 9 0.00535714285714286 1680 17224 54795,6331,2900,2898,6324,6334,41,6326,6328 TRPM4,SCN5A,GRIK4,GRIK2,SCN1B,SCN8A,ASIC1,SCN2A,SCN3A GO:0030170 pyridoxal phosphate binding 0.0303544446057254 -3.49481232719946 53 10 0.00595238095238095 1680 17224 84706,55034,51166,23464,875,85007,18,64850,2731,1491 GPT2,MOCOS,AADAT,GCAT,CBS,PHYKPL,ABAT,ETNPPL,GLDC,CTH GO:0070279 vitamin B6 binding 0.0303544446057254 -3.49481232719946 53 10 0.00595238095238095 1680 17224 84706,55034,51166,23464,875,85007,18,64850,2731,1491 GPT2,MOCOS,AADAT,GCAT,CBS,PHYKPL,ABAT,ETNPPL,GLDC,CTH GO:0072341 modified amino acid binding 0.0314004070743519 -3.46093442200063 76 13 0.00773809523809524 1680 17224 348751,2946,4139,115548,2948,114879,2194,2947,875,2621,9536,10125,85477 FTCDNL1,GSTM2,MARK1,FCHO2,GSTM4,OSBPL5,FASN,GSTM3,CBS,GAS6,PTGES,RASGRP1,SCIN GO:0004385 guanylate kinase activity 0.0314440363700093 -3.45954593639154 13 4 0.00238095238095238 1680 17224 1740,4354,260425,4355 DLG2,MPP1,MAGI3,MPP2 GO:0008195 phosphatidate phosphatase activity 0.0314440363700093 -3.45954593639154 13 4 0.00238095238095238 1680 17224 8611,64900,64748,8612 PLPP1,LPIN3,PLPPR2,PLPP2 GO:0050998 nitric-oxide synthase binding 0.0314440363700093 -3.45954593639154 13 4 0.00238095238095238 1680 17224 6331,26052,493,9722 SCN5A,DNM3,ATP2B4,NOS1AP GO:0039706 co-receptor binding 0.0314440363700093 -3.45954593639154 13 4 0.00238095238095238 1680 17224 652,120892,4756,22943 BMP4,LRRK2,NEO1,DKK1 GO:0015299 solute:proton antiporter activity 0.0319363714041046 -3.44400974928316 19 5 0.00297619047619048 1680 17224 55002,285335,150159,5002,84679 TMCO3,SLC9C1,SLC9B1,SLC22A18,SLC9A7 GO:0005003 ephrin receptor activity 0.0319363714041046 -3.44400974928316 19 5 0.00297619047619048 1680 17224 2042,4916,2051,2047,1944 EPHA3,NTRK3,EPHB6,EPHB1,EFNA3 GO:0031690 adrenergic receptor binding 0.0319363714041046 -3.44400974928316 19 5 0.00297619047619048 1680 17224 5144,9863,9693,4734,153 PDE4D,MAGI2,RAPGEF2,NEDD4,ADRB1 GO:0008081 phosphoric diester hydrolase activity 0.0323230549430923 -3.43197452804205 92 15 0.00892857142857143 1680 17224 5167,5153,133121,10846,284161,5151,147111,5337,5144,23236,81544,27293,10924,1131,2822 ENPP1,PDE1B,ENPP6,PDE10A,GDPD1,PDE8A,NOTUM,PLD1,PDE4D,PLCB1,GDPD5,SMPDL3B,SMPDL3A,CHRM3,GPLD1 GO:0030674 protein binding, bridging 0.0345490012645737 -3.36537663614507 167 24 0.0142857142857143 1680 17224 10451,6452,10580,8935,9047,2888,287,2059,3092,3512,91947,8631,1832,7373,10458,1123,1124,11161,4130,23767,90525,1310,2887,9846 VAV3,SH3BP2,SORBS1,SKAP2,SH2D2A,GRB14,ANK2,EPS8,HIP1,JCHAIN,ARRDC4,SKAP1,DSP,COL14A1,BAIAP2,CHN1,CHN2,ERG28,MAP1A,FLRT3,SHF,COL19A1,GRB10,GAB2 GO:0034987 immunoglobulin receptor binding 0.0356565596792977 -3.33382214682382 8 3 0.00178571428571429 1680 17224 3512,2268,2242 JCHAIN,FGR,FES GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor 0.0357488896154099 -3.3312360700333 26 6 0.00357142857142857 1680 17224 1717,645,79644,1718,56898,2194 DHCR7,BLVRB,SRD5A3,DHCR24,BDH2,FASN GO:0031624 ubiquitin conjugating enzyme binding 0.0369786737608867 -3.29741391735241 33 7 0.00416666666666667 1680 17224 54941,91694,285671,5071,154214,9781,23551 RNF125,LONRF1,RNF180,PRKN,RNF217,RNF144A,RASD2 GO:0030554 adenyl nucleotide binding 0.03774864824178 -3.276805612093 1514 168 0.1 1680 17224 349565,4598,2180,90,3798,10396,445,5578,16,8428,5891,9531,6196,1768,54805,2051,5567,5159,10188,4139,10257,130399,120892,5577,1244,93,4919,10110,157,9149,203,5167,10769,540,2081,5603,5287,144132,5563,833,7301,26524,860,11149,6334,9748,284716,26038,134266,116835,3480,57143,23461,10846,5592,222537,112,80216,55137,375449,5058,2264,4651,11001,11069,84033,55437,8476,55760,9261,57494,29941,3099,162394,79646,6296,2042,152110,4430,5596,4916,1147,2870,23046,780,91351,10290,440,83694,140469,92,22989,5144,4233,1767,3306,2241,2617,91807,5163,5208,4597,53354,107,5588,481,2444,79739,57205,260425,2260,7453,27010,953,64208,5579,5754,84451,657,5602,22983,23043,4642,8444,659,57144,10079,338323,3800,5028,5585,2047,5580,30845,2963,23678,59,6446,5593,79659,4646,6850,490,2242,5210,54795,26873,9693,81788,205,4141,23250,79834,57761,2268,10000,5608,79858,138429,55605,3098,79705,129607,51776,23095,493,9619,478 NMNAT3,MVK,ACSL1,ACVR1,KIF5A,ATP8A1,ASS1,PRKCA,AARS,STK24,MOK,BAG3,RPS6KA2,DNAH6,CNNM2,EPHB6,PRKACB,PDGFRB,TNK2,MARK1,ABCC4,ACVR1C,LRRK2,PRKAR2B,ABCC2,ACVR2B,ROR1,SGK2,GRK3,DYRK1B,AK1,ENPP1,PLK2,ATP7B,ERN1,MAPK13,PIK3C2B,DNHD1,PRKAA2,CARS,TYRO3,LATS2,RUNX2,BVES,SCN8A,SLK,RIMKLA,CHD5,GRPEL2,HSPA12B,IGF1R,ADCK1,ABCA5,PDE10A,PRKG1,HS3ST5,ADCY6,ALPK1,FIGN,MAST4,PAK1,FGFR4,MYO10,SLC27A2,RAPGEF4,OBSCN,STRADB,CDC42BPA,DHX32,MAPKAPK2,RIMKLB,PKN3,HK2,SLFN5,PANK3,ACSM3,EPHA3,NEK10,MYO1B,MAPK4,NTRK3,CHUK,GRK6,KIF21B,DDR1,DDX60L,SPEG,ASNS,RPS6KL1,MYO3B,ACVR2A,MYH15,PDE4D,MET,DNAH5,HSPA2,FER,GARS,MYLK3,PDK1,PFKFB2,MVD,PANK1,ADCY1,PRKCQ,ATP1B1,FRK,TTLL7,ATP10D,MAGI3,FGFR1,WARS,TPK1,ENTPD1,POPDC3,PRKCB,PTK7,MAP3K21,BMPR1A,MAPK10,MAST1,TNIK,MYO1D,DYRK3,BMPR2,PAK5,ATP9A,NLRP14,KIF5C,P2RY1,PKN1,EPHB1,PRKCD,EHD3,GTF2F2,SGK3,ACTA2,SGK1,PRKG2,DYNC2H1,MYO6,SYK,ATP2B1,FES,PFKFB4,TRPM4,OPLAH,RAPGEF2,NUAK2,AK4,MARS,ATP11A,PEAK1,TRIB3,FGR,AKT3,MAP2K6,NEK11,PIP5KL1,KIF21A,HK1,LRRK1,CMPK2,MAP3K20,KIF1B,ATP2B4,ABCG1,ATP1A3 GO:0005488 binding 0.0389046585754319 -3.24664127780494 14760 1464 0.871428571428571 1680 17224 23092,8563,161823,2898,8434,55283,51175,4869,1488,1050,63827,51429,54855,6497,81567,64376,5911,54732,5521,83548,1363,5455,389203,317649,151230,1630,23233,11034,120892,4774,9638,5577,1244,3752,8822,26512,5831,388507,6541,5167,644150,540,79884,56898,153,27113,81617,29767,2073,148252,22876,7168,144132,6331,3655,219749,7082,114781,29899,27241,2290,51440,1123,400961,200558,23767,57522,10960,9760,93664,157638,80216,79958,26002,55137,58494,25946,3786,54558,84159,80258,100289635,2274,2194,3092,51390,6616,79740,91947,1203,55812,57494,119391,6158,54814,140606,79789,55353,3239,1000,57698,387751,23348,92170,29842,9522,119,5596,2870,10560,7098,4102,286499,51121,22891,1767,4661,29887,9312,8321,91807,1292,2597,64168,125144,5208,79924,107,7481,1832,444,114991,260425,23710,953,3627,57584,27295,7466,100506013,3912,27314,114336,130940,23464,23621,5324,8325,54845,80381,638,337867,23362,875,2621,2047,51222,84707,3157,57060,2690,678,116931,83666,54795,9260,27077,7424,26873,51560,22821,205,23250,64324,6136,56129,5352,79858,138429,652,129607,493,1911,7093,116154,2258,10626,29995,57447,3709,146664,5358,8153,221184,285180,6196,51166,3690,744,9832,2023,9771,346157,1627,30818,4139,468,10957,1285,287,475,4779,1380,27244,131544,83985,9149,114088,83439,27345,3638,11278,2081,113146,148523,63973,123036,23266,143384,58528,91694,7301,860,3958,9515,283987,10174,7762,7546,5217,80206,56907,285671,2589,9253,253461,126070,80144,6525,8139,222537,4040,112,9443,9686,10970,56896,153579,11282,1944,26086,55437,9935,84033,221935,202559,10458,257194,55357,57666,5337,10371,79845,56935,3397,1793,4916,23046,22898,85456,55698,55607,91351,57556,149076,3422,10579,604,80820,22989,6591,3486,6207,27152,1447,23507,81550,59336,48,54941,8973,7431,28981,5795,154214,5802,3082,1501,54463,57221,23462,10178,55857,8444,54550,659,57144,55784,51655,56978,7265,93986,2963,8848,7020,6446,9729,6850,490,5046,1843,1112,1397,144165,10979,9941,23022,4255,27293,9454,22943,1879,951,23576,85440,2200,83699,6510,9536,23095,5569,781,9310,55366,3949,8673,5578,84679,7227,1890,57732,27143,2731,57222,130399,26249,8838,665,114327,2770,57630,649,5603,81848,8829,50859,10501,11279,9902,220108,23216,6480,4291,1718,29093,320,2619,57509,53342,3983,23657,55103,4858,57143,4609,338761,202,6720,91179,5592,23426,119587,375449,51334,91272,8643,6154,27185,7436,11069,8642,29763,7468,51555,10577,8476,157753,4324,130271,57161,7060,57728,81563,127255,4147,4355,51626,6713,51460,1717,162394,64754,4681,79867,29984,256309,4481,5362,100113407,7373,780,26230,9372,90060,10290,440,11161,220929,5462,230,90525,5144,9846,1787,51700,22941,53354,57580,57502,467,23314,25776,481,26108,474,57205,138162,3669,6622,10207,7552,22806,64208,27018,6999,8900,619279,3248,657,4281,85439,29942,23242,57531,4642,57088,3489,2059,3800,51191,54602,7164,3628,576,54103,222255,11228,219527,10265,2334,151393,79659,79603,23158,54206,4091,9331,30061,10451,6452,5829,217,64283,2946,5783,56895,6144,7347,3198,643836,7015,84898,4163,6840,79705,1649,23367,2180,81569,11099,25943,83872,2152,1687,113622,4072,22843,25890,7220,54805,2017,25924,3556,5159,1545,10188,83667,8935,23670,10413,23406,10110,2934,51704,10855,10827,5021,10891,7292,9863,84978,5125,84706,9899,55034,55893,9886,11149,29091,26272,150356,6319,22856,56122,100131997,50862,1938,7782,6940,55765,22998,64115,378925,23066,1052,51375,23361,57575,60437,3048,93974,50512,23433,2948,9672,26872,9709,9750,5325,2195,374383,23677,11031,11247,54874,26257,114880,23312,10580,9050,58504,57520,22837,80781,821,10464,963,85477,118987,8555,56605,8496,23254,65055,2172,92,2272,5627,144404,22854,93349,23532,118429,10076,5777,4597,79669,85012,79825,958,148266,53335,55509,55450,4111,81931,53840,3839,1978,348093,6001,142679,55819,22983,2026,23555,9826,54622,152189,6756,10673,79008,150864,10644,58495,654,90550,79187,26056,3761,6324,5580,8614,59,115123,84632,9840,5939,10687,84674,9099,10765,51232,3174,55638,387856,55616,79834,79623,10333,254827,9227,3953,9811,10910,3382,1896,390,1515,55075,6206,114804,3581,256302,4867,9619,8448,5153,55640,134353,5611,253559,6777,79094,55651,1795,767,9722,2070,5099,54749,9531,30850,7049,9858,114907,5366,1768,8499,25837,87769,7253,114821,7080,4212,4093,2706,7039,10486,79971,253827,2161,377677,10781,226,26137,51084,4026,4208,833,26524,55970,1573,9748,150737,134266,10388,51187,662,25825,783,85416,84171,4684,85460,6812,148979,178,114793,2674,6228,29967,1131,3156,10117,627,4860,4651,6775,4259,6262,10203,6604,5357,715,6875,10150,64506,55760,56271,6456,9508,84034,83729,1015,126433,7222,1466,685,170685,26052,9658,11013,79695,11226,348487,720,4430,57596,8601,5318,3597,3937,9378,10584,114112,2838,23136,57484,1138,8564,154043,51339,84570,219790,64219,5874,9143,282973,379,81704,55184,54961,2617,153830,8322,579,27133,10360,92370,23682,23331,2260,254042,8660,2995,90874,10400,25937,57480,8821,5066,57333,5033,9966,1628,3219,84281,10160,6092,60401,3843,5028,9586,5585,26262,85301,4756,168620,23263,283431,729967,4646,23467,2242,80329,605,167691,171425,9693,23101,83401,64762,10399,6641,57493,2591,5788,57761,3399,2775,10000,7494,114879,3098,6474,57572,8945,285761,3169,7178,349565,23321,91683,50810,445,10859,255928,54830,4857,56884,11328,7881,285966,8320,3781,3257,153562,1310,8825,83660,7099,2115,4703,3695,1604,6520,10257,284161,8612,59338,256536,10538,64943,58473,284618,3626,4133,8974,59345,9895,201798,7132,5287,1746,221749,4300,92421,5563,6004,85450,219654,84959,65997,26040,23209,8809,116835,2202,158405,56952,10505,3480,23461,590,2624,10846,664,25827,5058,337876,2264,11043,11001,81790,9455,6920,221178,8497,79446,5151,374618,197257,9261,91647,1435,26508,79646,54997,10736,2810,4311,5071,60370,3075,9495,54947,23543,55769,11237,27445,869,1496,1592,9715,55296,10247,26468,64429,140469,22859,134829,118738,2735,1491,51466,91147,7846,7390,29997,2257,9446,5919,90737,2444,64850,83700,725,4088,5903,10718,2633,5754,51225,3673,5413,55762,157773,1272,23324,54510,9170,9235,2888,9853,322,338323,2566,6402,3046,9912,5523,25851,4130,23551,10209,166336,285590,687,5106,2098,92597,9229,9645,5509,389643,9516,81788,22862,56654,54627,283078,65062,79633,91133,2329,7761,133923,388558,1740,745,6124,5083,56906,9882,57530,23077,90,57718,8712,54847,10396,8495,2625,55740,11174,5881,117154,16,8428,23413,5891,5002,23201,3078,26033,2947,11262,29993,4105,11123,5360,11138,341019,400954,2649,56062,9829,64798,27351,100271849,192670,7145,93,60485,10082,26084,57491,3131,3071,147372,10769,5924,57089,57821,10512,219699,23111,11178,63920,1948,3636,241,9620,1962,23051,5789,2561,6334,4983,9569,51477,6507,8794,1780,122622,26038,23521,79056,2122,26301,79955,118788,6307,27166,154661,220963,23554,8777,9699,220441,57669,54885,84725,100129654,23127,92104,94015,10567,55286,23236,26355,148156,747,56937,29941,23096,270,6296,5321,2042,9755,154810,27344,9462,6785,9781,282890,5013,115207,1147,26010,83594,23329,4753,152485,55603,134429,26960,9805,153090,4082,871,5163,79188,11166,84968,5588,125058,131566,3363,252884,5579,41,84451,688,2887,9474,5602,4306,284252,84321,160518,6224,10810,4601,10079,122616,402,6000,6414,81544,4734,84525,80853,26575,348751,8435,4245,23678,57186,5593,85007,9896,8531,55964,2672,10253,10924,5210,171024,116984,123688,4354,777,55917,2977,148206,8631,7545,1051,2268,9069,7703,283209,7286,2906,9172,11285,100506658,478,200035,23086,196264,4598,50865,3798,7358,79626,3512,18,785,54033,92737,22807,83999,23475,51303,1595,55160,6252,10382,23639,29841,9465,1750,79983,8739,26577,2051,5791,374378,92565,9353,10125,5567,51062,2823,147929,4919,22838,26297,157,2009,203,4685,135112,100127983,321,64919,2335,9871,122953,284716,79993,388403,285440,90423,114805,6304,26227,57211,54541,760,6205,57593,118812,56033,4846,30062,2660,9047,117583,80267,23286,1852,64409,639,64077,144193,577,115548,26064,3099,51162,64764,643,161436,57643,152110,3600,1951,54477,79710,11022,255877,144811,92181,1794,221833,79149,79047,83852,10497,83694,25925,9053,55240,80014,5452,4233,10794,3306,57628,25801,90102,2241,26136,55333,80005,79739,339448,7453,27010,9242,89782,60468,199990,54937,84976,113612,3977,5723,23043,1047,5966,4038,221078,64084,79004,6164,4825,1124,121355,30845,1829,9856,10612,128239,22800,8792,55033,54453,5865,4487,2104,3164,9265,55753,5638,4141,9749,116986,9743,900,23414,4131,473,170691,2861,92610,138151,257144,143098,54967,5547,5608,8140,55605,2669,51776,4325,2040,9751 ARHGAP26,THOC5,ADAL,GRIK2,RECK,MCOLN3,TUBE1,NPM1,CTBP2,CEBPA,BCAN,SNX9,TENT5C,SKI,TXNDC5,IKZF5,RAP2A,TMED9,PPP2R2B,COG3,CPE,POU3F3,SMIM20,EIF4E3,KLHL23,DCC,EXOC6B,DSTN,LRRK2,NFIA,FEZ1,PRKAR2B,ABCC2,KCND3,FGF17,INTS6,PYCR1,ZNF788P,SLC7A1,ENPP1,WIPF3,ATP7B,MAP9,BDH2,ADRB1,BBC3,CAB39L,TMOD2,ERCC5,DIRAS1,INPP5F,TPM1,DNHD1,SCN5A,ITGA6,ZNF25,TJP1,BTBD9,GPSM2,BBS9,FOXG1,HPCAL4,CHN1,PAIP2B,APLF,FLRT3,SRGAP1,LMAN2,TOX,CADPS2,FAM84B,ALPK1,DENND1C,MOXD1,FIGN,JAM2,ZNF385A,KCNQ3,SPATA6,ARID5B,EFHC2,ZNF605,FHL2,FASN,HIP1,AIG1,SNAP25,ZBBX,ARRDC4,CLN5,SPATA7,RIMKLB,GSTO2,RPL28,QPCTL,SELENOM,CLMN,LAPTM4B,HOXD13,CDH2,SHTN1,GVINP1,DOCK9,MTG1,TFCP2L1,SCAMP1,ADD2,MAPK4,GRK6,SLC19A2,TLR3,MAGEA3,FAM133A,RPL26L1,ZNF365,DNAH5,MYT1,SNX10,KCNB2,FZD1,MYLK3,COL6A2,GAPDH,NECAB1,LRRC75A-AS1,PFKFB2,ADM2,ADCY1,WNT11,DSP,ASPH,ZNF618,MAGI3,GABARAPL1,ENTPD1,CXCL10,ARHGAP21,PDLIM3,WFS1,APELA,LAMB1,RAB30,CGB2,CCDC148,GCAT,BACE1,PLAG1,FZD8,ESRP1,CD276,BIK,UBAC2,PSD3,CBS,GAS6,EPHB1,ZNF219,BEX2,HMGCS1,PCBP4,GHR,ZFP36L2,MED12L,PARP9,TRPM4,PDLIM7,B9D1,VEGFC,OPLAH,RAB6B,RASA3,AK4,ATP11A,NSD1,RPL12,PCDHB7,PLOD2,NEK11,PIP5KL1,BMP4,CMPK2,ATP2B4,PHC1,TLL2,PHACTR3,FGF13,TRIM16,LMCD1,NDRG2,ITPR2,MGAT5B,PLS3,RND2,CPNE2,RUFY4,RPS6KA2,AADAT,ITGB3,MPPED2,JAKMIP2,ENO1,RAPGEF5,ZNF391,DBN1,KCNIP3,MARK1,ATF4,PNRC1,COL4A3,ANK2,ATOX1,NFE2L1,CR2,SESN1,CRYBG3,SPNS1,DYRK1B,TRIM9,TCF7L1,KCNMB4,INSIG1,KLF12,ERN1,AHNAK2,CIART,NEUROG2,TC2N,ADGRL2,CACUL1,RRAGD,LONRF1,TYRO3,RUNX2,LGALS3,STXBP5L,HID1,SORBS3,ZNF215,ZIC2,PFN2,FHOD3,SPIRE1,RNF180,GALNT1,NUMBL,ZBTB38,ZNF440,FRAS1,SMTN,GAN,HS3ST5,LRP6,ADCY6,MED7,VGLL4,CKAP4,DPYSL5,BTNL9,MGAT4B,EFNA3,GPSM1,STRADB,MAFB,OBSCN,SDK1,KHDRBS2,BAIAP2,NEGR1,TBC1D2,FBRSL1,PLD1,SEMA3A,RNF122,SMCO4,ID1,DOCK1,NTRK3,KIF21B,DENND3,TNKS1BP1,RADIL,PPP1R9A,DDX60L,SEMA6A,ZNF362,IDI1,TACC2,BCL6,EEPD1,MYH15,SNAI2,IGFBP3,RPS13,INTU,CSN2,LRRC8B,TDRD3,PRDM13,ACO1,RNF125,CHRNA6,VIM,IFT81,PTPRJ,RNF217,PTPRS,HGF,CTNND2,RETREG1,ARFGEF3,HEY1,TENM1,KIZ,DYRK3,NECAB2,BMPR2,PAK5,MCTP2,RASD1,PRDM8,TTC1,FOXP2,GTF2F2,TSC22D1,TFAP2A,SGK1,KIAA0408,SYK,ATP2B1,PCSK6,DUSP1,FOXN3,CRIP2,PRICKLE1,FERMT2,EXOG,PALLD,MGMT,SMPDL3B,HOMER3,DKK1,EBF1,CD37,DDAH1,DOCK7,FBN1,SH3BGRL2,SLC1A5,PTGES,KIF1B,PKIA,CACNA2D1,ZNF235,LGR4,LDLR,VAMP8,PRKCA,SLC9A7,TRPS1,TYMP,ZFYVE28,PALD1,GLDC,ERGIC1,ACVR1C,KLHL3,WISP3,BNIP3L,EFHC1,GNAI1,SH3RF1,BMP1,MAPK13,SPRY4,NRP1,SPOCK3,SEMA6B,KLF8,MRC2,FAM124A,TBC1D1,ST6GAL1,MLF1,DHCR24,MRPL22,APBA1,GAS1,MTUS1,IL17D,ABLIM1,SLC7A11,RALGPS2,NOVA2,ADCK1,MYC,C1QL4,CRYBG1,SREBF1,SCARF2,PRKG1,GRIP1,CPXM2,MAST4,PRR16,BOD1,PTCH2,RPL26,DISC1,VLDLR,RAPGEF4,DCHS1,PACSIN3,NSD2,PEX5L,NPC2,CDC42BPA,TMEM74,MMP15,PLEKHH2,PELI2,THBS4,WDR19,C1orf21,LRRIQ3,MATN2,MPP2,DYNC2LI1,SQLE,SFMBT1,DHCR7,SLFN5,SMYD3,NBL1,TCTN2,RHOD,CCDC110,MSR1,PLXNA2,TMEM170B,COL14A1,DDR1,TIAM2,ZFYVE9,CCDC120,SPEG,ASNS,ERG28,ZNF438,POU5F1B,ALDOC,SHF,PDE4D,GAB2,TRDMT1,CYB5R2,SHANK2,PANK1,PREX1,NLGN4X,ATF3,SATB2,CBY1,ATP1B1,PYGO1,ATOH1,ATP10D,C9orf116,ISG20,SNCA,PATJ,ZNF711,IKZF3,POPDC3,BEX3,TDO2,CCNA1,ZNF704,HPGD,BMPR1A,MID1,STON2,PURG,COBL,HACE1,MYO1D,PLSCR4,IGFBP6,EPS8,KIF5C,HERC5,NDFIP2,TPD52L1,INPP1,ADGRB2,GSAP,ATXN7L1,RASSF8,LRRC55,IRX5,AFF2,RMDN2,DYNC2H1,CERS4,TBC1D9,ERRFI1,SMAD6,B4GALT6,SLC40A1,VAV3,SH3BP2,PXN,ALDH2,ARHGEF28,GSTM2,PTPN13,AGPAT4,RPL21,UCHL3,HOXA1,ZFP62,TERT,PLXDC2,MCC,SVIL,LRRK1,DDIT3,LARP1,ACSL1,ACTL8,PTPN21,C20orf194,HMCN1,F3,GSDME,ADPRHL1,EPCAM,PPM1E,ABI3BP,TRPC1,CNNM2,CTTN,MYRIP,IL1RAP,PDGFRB,CYP1B1,TNK2,SESN2,SKAP2,CEMIP2,YAP1,COTL1,SGK2,GSN,GPRC5B,HPSE,FAM114A2,OXTR,PPARGC1A,TNFSF4,MAGI2,FRMD5,PCSK5,GPT2,SV2B,MOCOS,ZNF395,RHOBTB1,BVES,STXBP6,FBXO4,CHADL,SCD,CHSY1,PCDHB14,FAM27E3,RNF141,EEF2,SLC30A4,ZNF354A,INAVA,LIMCH1,VSIR,RNF148,CAND2,CEBPD,SNX7,ZNF629,PCDH10,CDH26,HBG2,ATP5IF1,PODXL2,RHOQ,GSTM4,SDC3,STEAP1,HERPUD1,RIPOR2,PLAGL1,FAT1,NCR3LG1,SH3BP4,RAB31,NXPH4,FNBP1L,NKX2-8,OSBPL6,DMXL2,SORBS1,PSTPIP2,ARHGAP22,HECW2,COBLL1,COL18A1,CANX,PIBF1,CD53,SCIN,PDZD8,CDC14B,ERO1B,PPFIBP1,KAZN,REEP1,FABP6,ACVR2A,FHIT,PROS1,TMEM120B,NTNG1,SP140L,PRAME,ANTXR2,PTPRU,PTPN6,MVD,C3orf52,TCEAL3,EFCC1,CD40,ZNF569,BCL11A,BATF3,CAMK2N1,MAGEA12,ZNF93,TRIM34,KPNA3,EIF4EBP1,RBPMS2,RGS10,DUSP19,RNF130,MAST1,ENO2,TSPAN15,ARHGEF11,ARL15,CMTM8,SSX1,TNFSF13B,SLX1B,FAM117B,IGF2BP2,OVOL2,BMP6,MCU,FSD1,RAB11FIP5,KCNJ4,SCN1B,PRKCD,STC2,ACTA2,MARCH3,AFAP1L2,TESPA1,RBMS2,PNMA2,CARD6,USP2,KDM5B,CRIM1,HNF4G,SYBU,CCDC184,ASAP3,PEAK1,GALNT14,TLR6,NAALADL2,LRAT,LEPR,CTIF,SUGT1,ICA1,EDA,RND3,CTSV,UACA,RPS12,RNF157,IL9R,NATD1,NPHP1,ABCG1,DOC2A,PDE1B,FLVCR2,LSM11,DNAJC3,CADM2,STAT5B,CHAC1,NHP2,DOCK3,CA8,NOS1AP,EYA4,PCDH7,EPDR1,BAG3,CDR2L,TGFBR3,PPP1R26,FBXO32,PMAIP1,DNAH6,PPFIA2,RAB26,GGACT,TSHR,ZBED9,NKX2-1,MEIS2,SMAD9,GJB2,TGFA,CAP2,WLS,MSRB3,F12,CA13,ZNF266,ALDOA,ZBTB20,CRYL1,LPP,MEF2C,CARS,LATS2,GNG12,CYP2J2,SLK,TTC30B,GRPEL2,SYCP2,RSL24D1,BNIP1,BACE2,CACNB2,ZIC5,LOXL4,NCAM1,ZNF518B,STXBP1,GLIS1,AGL,FMNL2,GFRA1,RPS23,LRP12,CHRM3,HMGCR,ENAM,BDNF,PNP,MYO10,STAT4,MGST3,RYR2,CALCRL,SMARCD3,PLS1,C1R,TAF4B,MBNL2,CPEB1,DHX32,BEX4,SH3GL2,ADAMTS3,EMILIN2,INHBE,CDH17,FBXO27,TRPC3,CSRP2,BTC,NUDT10,DNM3,ZNF516,TMSB15A,GALNT12,GALNT6,FAM131C,C4A,MYO1B,BEGAIN,RGS20,PKP2,IL13RA1,LCP2,NRXN1,COLEC10,TXNRD3,GPR15,EPB41L3,RNF150,CHRNA5,KMO,CNKSR3,DACT1,COL25A1,RTKN2,PJA1,RAB27B,SYNGR3,JAKMIP3,ARL4D,DOCK8,DZANK1,SSH3,GARS,RNF145,FZD4,NKX3-2,KCNH5,NPM3,PXYLP1,RAB38,TTC28,FGFR1,METAP1D,IRS2,GYPC,ZNF697,PEMT,WWTR1,PLEKHG1,INPP4B,PAM,RCN3,P4HA1,TNFSF15,DBP,HOXB9,C2orf88,FARP1,ROBO2,EDA2R,IPO5,P2RY1,CREB5,PKN1,TSPAN17,COL27A1,NEO1,BHLHA15,MCF2L,GAS2L3,MORN2,MYO6,NPTXR,FES,ULBP1,BCL7A,LCA5,CLYBL,RAPGEF2,MCF2L2,ELOVL3,GAREM1,RACK1,SNTB1,HEG1,GALNT3,PTPRC,TRIB3,ID3,GNAO1,AKT3,XBP1,OSBPL5,HK1,SHOX2,DOCK6,BTRC,DCBLD1,FOXA1,TPT1,NMNAT3,TRIM2,SYT12,HDGFL3,ASS1,LILRB1,SYT14,NUP62CL,NOVA1,FSTL5,FKBP9,KCNAB1,TCAF2,EOMES,KCNN2,HPS1,MARVELD2,COL19A1,LIN7A,TLN2,TLR4,ETV1,NEB,ITGB7,CD55,SLC3A2,ABCC4,GDPD1,PLPP2,PLEKHA1,TCERG1L,BATF,NT5DC2,PLEKHB1,RUSC1-AS1,INHBC,MAP2,P4HA2,GNB4,TECPR2,TIGD4,TNFRSF1A,PIK3C2B,DLX2,PXDC1,MLLT3,CHMP4C,PRKAA2,RGS16,ITPRIP,ZCCHC24,UBASH3B,RASL11B,SETBP1,MLC1,IL18R1,HSPA12B,EFEMP1,KIAA1958,PRTFDC1,SEMA4F,IGF1R,ABCA5,BCHE,GATA2,PDE10A,BNIP3,FBXL2,PAK1,CHSY3,FGFR4,MID2,SLC27A2,RNF170,HOMER2,TCEA3,SPATA13,PPFIA4,WDR25,PDE8A,TEX9,LDHD,MAPKAPK2,ATPAF2,CSF1,HEYL,PANK3,TESC,SIX2,SFN,MME,PRKN,AVPI1,CFH,AKAP5,LPCAT2,RBFOX2,ZNF83,RNF24,PCLO,CBLN1,CTNNA2,CYP26A1,FAM131B,TBC1D19,RIDA,LHX6,ZDHHC6,MYO3B,ADGRL1,CLVS2,ZNF488,GLI1,CTH,EVL,TMEM67,TUBA1A,UROS,NOP53,FGF12,GSTO1,RARRES2,PAGE5,FRK,ETNPPL,JAM3,C4BPB,SMAD3,RANBP2,NRG3,GBP1,PTK7,ABI3,ITGA2,SEPT5,ZNF701,C8orf48,CNTN1,MAN2B2,PCDH18,LPAR2,IL32,GRB14,RUSC2,APBB1,NLRP14,GABRG2,SELL,HBE1,ARHGAP44,PPP2R3A,TECPR1,MAP1A,RASD2,EIF1,PRICKLE2,SH3PXD2B,KLF9,PCK2,ESD,MOB1B,DLGAP1,MICAL2,PPP1R3D,NUGGC,LITAF,NUAK2,FNDC3A,NPDC1,MAP10,MKX,TMEM237,FAT4,L3MBTL4,FMO4,ZNF214,ZNF474,ZNF808,DLG2,MYRF,RPL4,PAX9,THAP10,TBC1D4,CGN,MYCBP2,ACVR1,PPP4R4,PAGE1,SIDT1,ATP8A1,PPFIBP2,GATA3,ENAH,ADAMTS6,RAC3,DACH2,AARS,STK24,NCS1,MOK,SLC22A18,FAM168A,CFHR1,ATRNL1,GSTM3,SP140,PACSIN1,MAGEA6,RCAN3,PLTP,TBC1D8,DCDC1,EML6,NR6A1,KLHL4,DNAJC6,DEPTOR,DESI1,MEF2B,AGO4,TNS1,ACVR2B,SAV1,GPC6,ARHGEF26,AHRR,HLF,NCKAP1L,CCBE1,PLK2,RASGRF2,ENTPD7,CCDC181,SEMA3C,UNC5B,SPART,LZTS1,ZBED8,EFNB2,INPPL1,ALOX5AP,CELSR1,EHHADH,ZHX3,PTPRD,GABRB2,SCN8A,OPHN1,GTF2IRD1,ISYNA1,SLC1A3,TNFRSF10C,DYNC1I1,ADSSL1,CHD5,RPL13A,PRRG4,MECOM,GBGT1,PDZD7,PIK3AP1,MSMO1,PRELID1,RUNDC3B,SLC16A9,TSPAN12,MPDZ,RIMS2,RNF152,EPB41L5,TBC1D8B,PLEKHA8,TCF24,COLGALT2,TTC30A,TTYH2,RABAC1,C4orf19,PLCB1,FAM162A,ZNF558,DAGLA,PMEPA1,PKN3,IQSEC2,AMPD1,ACSM3,PLA2G4A,EPHA3,TBKBP1,AMOTL1,PCSK1N,RASAL2,ELOVL4,RNF144A,ZNF311,OTX1,KCTD12,CHUK,SPATS2L,NUDT12,TBC1D30,NELL2,ZNF827,TENT5A,STARD4,NBEA,SCRN1,DAB2IP,MARCKS,SERPINH1,PDK1,TMEM43,SOX21,PNMA6A,PRKCQ,TBC1D16,DCBLD2,HTR7,ZNF396,PRKCB,ASIC1,MAP3K21,KLF5,GRB10,ATG5,MAPK10,NR3C2,KCTD1,THOC3,DENND5B,RPS20,WASF3,MXI1,ATP9A,CLBA1,ARL2,RGS7,SELENOP,GDPD5,NEDD4,HOPX,KDM7A,RGS17,FTCDNL1,SOAT2,MGAT1,SGK3,RALGAPA2,PRKG2,PHYKPL,FIG4,YBX3,SEPT3,GFI1,SPRY2,SMPDL3A,PFKFB4,SYNPO2,ARAP2,HYKK,MPP1,CACNA1E,CTTNBP2NL,GUCY1A2,ZNF714,SKAP1,ZIC1,CEBPB,FGR,CLDN12,PCGF2,PGM2L1,TUFT1,GRIN2D,MYOM2,B4GALT7,OCLN,ATP1A3,NUDT17,EXPH5,MPZL3,MVK,HEBP1,KIF5A,UGDH,TNFAIP8L2,JCHAIN,ABAT,CACNB4,RBM11,DNER,IKZF2,KREMEN1,QPRT,FKBP11,CYP51A1,ARHGEF10L,RTN1,TUBB4A,LRRC6,GRHL1,AKAP7,DLX6,POF1B,HRK,PCOLCE2,EPHB6,PTPRE,GALNT18,FANK1,SLIT2,RASGRP1,PRKACB,ATL1,GPM6A,ZNF565,ROR1,RNF44,SERGEF,GRK3,EML1,AK1,NCAM2,NCOA7,C8orf88,APBA2,BCL11B,FN1,SEC24D,JDP2,RIMKLA,ELOVL7,YPEL2,CYP4V2,ATP6V1E2,GALNT13,SATB1,PHGDH,ADGRG6,DDIT4,CA2,RPS11,EBF4,MORN4,BARX1,NOS3,RAX,MSTN,SH2D2A,PARD3B,EDEM3,WWC1,DUSP9,GALNT17,PRDM1,LHPP,AMDHD1,ADGRB3,FCHO2,RAI14,HK2,EGFL7,CREB3L2,CXCR5,EML5,ZSWIM5,NEK10,IL15,CELSR3,PLEKHA5,MORC4,TDRKH,BCL6B,LACC1,UBTD2,DOCK2,SP8,ZSCAN5A,KCTD15,SETDB2,UNC13B,RPS6KL1,ZNF521,MAP7,STEAP3,WWC2,POU2F2,MET,ZNF460,HSPA2,DPP10,GCA,PHLDB2,FER,TES,SYNJ2BP,DOCK5,TTLL7,C1orf174,WARS,TPK1,MSC,LMLN,BACH2,FAAP20,SOHLH2,DISP1,CYP2U1,LIFR,PSPH,TNIK,CLGN,REL,LRP4,NSUN6,CLSTN2,CUEDC2,RPL34,NKX6-1,CHN2,GTSF1,EHD3,DSG2,KIAA0319,TRIM3,IQGAP3,RRAS2,TNFRSF11A,FKBP14,RIN2,RAB3B,MSX1,ESRRG,NR4A1,CYTH3,OGDHL,PRRG1,MARS,PHACTR2,AGAP2,ARHGAP32,CCNG1,ZFPM2,MAP1B,RERE,ADAMTS17,GPR37,TIFA,NACC2,GCSAM,MPP7,CT55,PRCP,MAP2K6,SLC7A5,KIF21A,GEM,MAP3K20,MMP16,STOM,SNPH GO:0000287 magnesium ion binding 0.0396102459260014 -3.22866745868287 195 27 0.0160714285714286 1680 17224 8444,4139,2026,171425,10079,10396,81788,8476,64077,23250,57205,23413,6622,2770,113622,56952,6196,5911,2081,2669,375449,2023,51776,54997,5723,5567,22983 DYRK3,MARK1,ENO2,CLYBL,ATP9A,ATP8A1,NUAK2,CDC42BPA,LHPP,ATP11A,ATP10D,NCS1,SNCA,GNAI1,ADPRHL1,PRTFDC1,RPS6KA2,RAP2A,ERN1,GEM,MAST4,ENO1,MAP3K20,TESC,PSPH,PRKACB,MAST1 GO:0005160 transforming growth factor beta receptor binding 0.0402362282625056 -3.21298748863474 48 9 0.00535714285714286 1680 17224 4088,3626,7049,2660,83729,65997,652,4091,654 SMAD3,INHBC,TGFBR3,MSTN,INHBE,RASL11B,BMP4,SMAD6,BMP6 GO:0005041 low-density lipoprotein particle receptor activity 0.0407089259438745 -3.20130789991835 14 4 0.00238095238095238 1680 17224 4040,3949,29967,7436 LRP6,LDLR,LRP12,VLDLR GO:0005161 platelet-derived growth factor receptor binding 0.0407089259438745 -3.20130789991835 14 4 0.00238095238095238 1680 17224 5795,3690,5159,2081 PTPRJ,ITGB3,PDGFRB,ERN1 GO:0005095 GTPase inhibitor activity 0.0407089259438745 -3.20130789991835 14 4 0.00238095238095238 1680 17224 402,10188,9353,3843 ARL2,TNK2,SLIT2,IPO5 GO:0005092 GDP-dissociation inhibitor activity 0.0407089259438745 -3.20130789991835 14 4 0.00238095238095238 1680 17224 29899,83667,23677,26086 GPSM2,SESN2,SH3BP4,GPSM1 GO:0032559 adenyl ribonucleotide binding 0.0435807692618337 -3.1331392979043 1502 166 0.0988095238095238 1680 17224 349565,4598,2180,90,3798,10396,445,5578,16,8428,5891,6196,1768,54805,2051,5567,5159,10188,4139,10257,130399,120892,5577,1244,93,4919,10110,157,9149,203,5167,10769,540,2081,5603,5287,144132,5563,833,7301,26524,860,11149,6334,9748,284716,26038,116835,3480,57143,23461,10846,5592,222537,112,80216,55137,375449,5058,2264,4651,11001,11069,84033,55437,8476,55760,9261,57494,29941,3099,162394,79646,6296,2042,152110,4430,5596,4916,1147,2870,23046,780,91351,10290,440,83694,140469,92,22989,5144,4233,1767,3306,2241,2617,91807,5163,5208,4597,53354,107,5588,481,2444,79739,57205,260425,2260,7453,27010,953,64208,5579,5754,84451,657,5602,22983,23043,4642,8444,659,57144,10079,338323,3800,5028,5585,2047,5580,30845,2963,23678,59,6446,5593,79659,4646,6850,490,2242,5210,54795,26873,9693,81788,205,4141,23250,79834,57761,2268,10000,5608,79858,138429,55605,3098,79705,129607,51776,23095,493,9619,478 NMNAT3,MVK,ACSL1,ACVR1,KIF5A,ATP8A1,ASS1,PRKCA,AARS,STK24,MOK,RPS6KA2,DNAH6,CNNM2,EPHB6,PRKACB,PDGFRB,TNK2,MARK1,ABCC4,ACVR1C,LRRK2,PRKAR2B,ABCC2,ACVR2B,ROR1,SGK2,GRK3,DYRK1B,AK1,ENPP1,PLK2,ATP7B,ERN1,MAPK13,PIK3C2B,DNHD1,PRKAA2,CARS,TYRO3,LATS2,RUNX2,BVES,SCN8A,SLK,RIMKLA,CHD5,HSPA12B,IGF1R,ADCK1,ABCA5,PDE10A,PRKG1,HS3ST5,ADCY6,ALPK1,FIGN,MAST4,PAK1,FGFR4,MYO10,SLC27A2,RAPGEF4,OBSCN,STRADB,CDC42BPA,DHX32,MAPKAPK2,RIMKLB,PKN3,HK2,SLFN5,PANK3,ACSM3,EPHA3,NEK10,MYO1B,MAPK4,NTRK3,CHUK,GRK6,KIF21B,DDR1,DDX60L,SPEG,ASNS,RPS6KL1,MYO3B,ACVR2A,MYH15,PDE4D,MET,DNAH5,HSPA2,FER,GARS,MYLK3,PDK1,PFKFB2,MVD,PANK1,ADCY1,PRKCQ,ATP1B1,FRK,TTLL7,ATP10D,MAGI3,FGFR1,WARS,TPK1,ENTPD1,POPDC3,PRKCB,PTK7,MAP3K21,BMPR1A,MAPK10,MAST1,TNIK,MYO1D,DYRK3,BMPR2,PAK5,ATP9A,NLRP14,KIF5C,P2RY1,PKN1,EPHB1,PRKCD,EHD3,GTF2F2,SGK3,ACTA2,SGK1,PRKG2,DYNC2H1,MYO6,SYK,ATP2B1,FES,PFKFB4,TRPM4,OPLAH,RAPGEF2,NUAK2,AK4,MARS,ATP11A,PEAK1,TRIB3,FGR,AKT3,MAP2K6,NEK11,PIP5KL1,KIF21A,HK1,LRRK1,CMPK2,MAP3K20,KIF1B,ATP2B4,ABCG1,ATP1A3 GO:0005525 GTP binding 0.0441309859465986 -3.12059311408308 366 46 0.0273809523809524 1680 17224 92170,26052,9886,29984,54622,402,51175,65997,51655,122622,5881,10382,8153,1938,5911,23551,30845,25837,5106,379,5874,55964,22800,51062,5865,23433,7846,51560,389643,120892,205,116986,23682,2977,2770,390,2775,2633,11031,148252,79705,2669,5413,27314,387751,58528 MTG1,DNM3,RHOBTB1,RHOD,ARL15,ARL2,TUBE1,RASL11B,RASD1,ADSSL1,RAC3,TUBB4A,RND2,EEF2,RAP2A,RASD2,EHD3,RAB26,PCK2,ARL4D,RAB27B,SEPT3,RRAS2,ATL1,RAB3B,RHOQ,TUBA1A,RAB6B,NUGGC,LRRK2,AK4,AGAP2,RAB38,GUCY1A2,GNAI1,RND3,GNAO1,GBP1,RAB31,DIRAS1,LRRK1,GEM,SEPT5,RAB30,GVINP1,RRAGD GO:1990939 ATP-dependent microtubule motor activity 0.0451909360549005 -3.09685874201157 49 9 0.00535714285714286 1680 17224 1768,3798,51626,3800,79659,144132,1767,1780,23095 DNAH6,KIF5A,DYNC2LI1,KIF5C,DYNC2H1,DNHD1,DNAH5,DYNC1I1,KIF1B GO:0022832 voltage-gated channel activity 0.0465596679665965 -3.067020606886 198 27 0.0160714285714286 1680 17224 27012,6331,30818,10368,3786,777,6334,27133,2621,3752,3749,785,23413,3761,219527,60598,7881,6324,783,3755,3790,2906,140738,6326,6328,9312,781 KCNV1,SCN5A,KCNIP3,CACNG3,KCNQ3,CACNA1E,SCN8A,KCNH5,GAS6,KCND3,KCNC4,CACNB4,NCS1,KCNJ4,LRRC55,KCNK15,KCNAB1,SCN1B,CACNB2,KCNG1,KCNS3,GRIN2D,TMEM37,SCN2A,SCN3A,KCNB2,CACNA2D1 GO:0005244 voltage-gated ion channel activity 0.0465596679665965 -3.067020606886 198 27 0.0160714285714286 1680 17224 27012,6331,30818,10368,3786,777,6334,27133,2621,3752,3749,785,23413,3761,219527,60598,7881,6324,783,3755,3790,2906,140738,6326,6328,9312,781 KCNV1,SCN5A,KCNIP3,CACNG3,KCNQ3,CACNA1E,SCN8A,KCNH5,GAS6,KCND3,KCNC4,CACNB4,NCS1,KCNJ4,LRRC55,KCNK15,KCNAB1,SCN1B,CACNB2,KCNG1,KCNS3,GRIN2D,TMEM37,SCN2A,SCN3A,KCNB2,CACNA2D1 GO:0019842 vitamin binding 0.0466769230297486 -3.06450538997996 138 20 0.0119047619047619 1680 17224 84706,55034,23464,55753,2194,875,18,64850,9227,27010,10265,348751,51166,5352,8974,5066,5033,85007,1491,2731 GPT2,MOCOS,GCAT,OGDHL,FASN,CBS,ABAT,ETNPPL,LRAT,TPK1,IRX5,FTCDNL1,AADAT,PLOD2,P4HA2,PAM,P4HA1,PHYKPL,CTH,GLDC GO:0004721 phosphoprotein phosphatase activity 0.0474298751594943 -3.04850297119617 181 25 0.0148809523809524 1680 17224 5509,54961,1850,10076,5789,5777,5783,84959,11099,9829,8612,1852,64077,2070,5788,22843,5795,8555,27143,142679,5799,5802,5521,5791,1843 PPP1R3D,SSH3,DUSP8,PTPRU,PTPRD,PTPN6,PTPN13,UBASH3B,PTPN21,DNAJC6,PLPP2,DUSP9,LHPP,EYA4,PTPRC,PPM1E,PTPRJ,CDC14B,PALD1,DUSP19,PTPRN2,PTPRS,PPP2R2B,PTPRE,DUSP1 GO:0008483 transaminase activity 0.0475317100831944 -3.04635820997558 21 5 0.00297619047619048 1680 17224 84706,85007,18,51166,64850 GPT2,PHYKPL,ABAT,AADAT,ETNPPL GO:0045499 chemorepellent activity 0.0475317100831944 -3.04635820997558 21 5 0.00297619047619048 1680 17224 10512,10718,10505,10371,23767 SEMA3C,NRG3,SEMA4F,SEMA3A,FLRT3 GO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding 0.0482462573794317 -3.0314370214713 1624 178 0.105952380952381 1680 17224 2625,6777,1050,22807,117154,7227,6497,64376,8320,29841,1750,2115,2023,114821,5455,346157,7080,30818,468,4212,4093,2649,4774,147929,4779,100271849,10538,388507,57491,83439,10781,3131,11278,26137,1746,63973,63920,4300,4208,64919,11279,860,55893,23051,219749,122953,9569,26040,7762,7546,6304,2290,2122,158405,253461,6940,126070,2624,4609,85416,6720,57593,85460,148979,56033,25946,1052,23361,30062,6775,84159,100289635,7468,9935,639,6875,148156,5325,26508,3239,26257,10736,64764,29842,3397,9658,282890,5013,55769,255877,221833,79149,149076,220929,5462,26468,604,25925,5452,10794,4661,57670,93349,6591,2735,11166,579,59336,23314,467,474,114991,55509,53335,148266,7552,252884,4088,9242,81931,22806,60468,90874,54937,688,657,1628,3219,4306,29942,55762,23462,4601,5966,5324,56978,9586,58495,51222,84525,4825,93986,10265,168620,7020,8848,687,8531,4091,2672,678,4487,10765,3174,1112,2104,3164,9516,23414,3198,7545,283078,473,1879,643836,1051,3399,138151,7761,7494,388558,745,5083,56906,6474,3169,1649,9310 GATA3,STAT5B,CEBPA,IKZF2,DACH2,TRPS1,SKI,IKZF5,EOMES,GRHL1,DLX6,ETV1,ENO1,ZBED9,POU3F3,ZNF391,NKX2-1,KCNIP3,ATF4,MEIS2,SMAD9,NR6A1,NFIA,ZNF565,NFE2L1,MEF2B,BATF,ZNF788P,AHRR,TCF7L1,ZNF266,HLF,KLF12,ZBTB20,DLX2,NEUROG2,ZBED8,MLLT3,MEF2C,BCL11B,KLF8,RUNX2,ZNF395,ZHX3,ZNF25,JDP2,GTF2IRD1,SETBP1,ZNF215,ZIC2,SATB1,FOXG1,MECOM,KIAA1958,ZBTB38,ZNF354A,ZNF440,GATA2,MYC,ZIC5,SREBF1,EBF4,ZNF518B,GLIS1,BARX1,ZNF385A,CEBPD,ZNF629,RAX,STAT4,ARID5B,ZNF605,NSD2,MAFB,PRDM1,TAF4B,ZNF558,PLAGL1,HEYL,HOXD13,NKX2-8,SIX2,CREB3L2,TFCP2L1,ID1,ZNF516,ZNF311,OTX1,ZNF83,BCL6B,SP8,ZSCAN5A,ZNF362,ZNF438,POU5F1B,LHX6,BCL6,ZNF521,POU2F2,ZNF460,MYT1,KIAA1549,SP140L,SNAI2,GLI1,SOX21,NKX3-2,PRDM13,SATB2,ATF3,ATOH1,ZNF618,BATF3,BCL11A,ZNF569,ZNF711,ZNF396,SMAD3,MSC,ZNF93,IKZF3,BACH2,ZNF697,SOHLH2,KLF5,BMPR1A,DBP,HOXB9,NR3C2,PURG,ZNF701,HEY1,MXI1,REL,PLAG1,PRDM8,CREB5,OVOL2,ZNF219,HOPX,NKX6-1,FOXP2,IRX5,BHLHA15,TFAP2A,TSC22D1,KLF9,YBX3,SMAD6,GFI1,ZFP36L2,MSX1,KDM5B,HNF4G,FOXN3,ESRRG,NR4A1,LITAF,ZFPM2,HOXA1,ZIC1,MKX,RERE,EBF1,ZFP62,CEBPB,ID3,NACC2,ZNF214,XBP1,ZNF808,MYRF,PAX9,THAP10,SHOX2,FOXA1,DDIT3,ZNF235 GO:0032550 purine ribonucleoside binding 0.0494815919453838 -3.0061545584632 369 46 0.0273809523809524 1680 17224 92170,26052,9886,29984,54622,402,51175,65997,51655,122622,5881,10382,8153,1938,5911,23551,30845,25837,5106,379,5874,55964,22800,51062,5865,23433,7846,51560,389643,120892,205,116986,23682,2977,2770,390,2775,2633,11031,148252,79705,2669,5413,27314,387751,58528 MTG1,DNM3,RHOBTB1,RHOD,ARL15,ARL2,TUBE1,RASL11B,RASD1,ADSSL1,RAC3,TUBB4A,RND2,EEF2,RAP2A,RASD2,EHD3,RAB26,PCK2,ARL4D,RAB27B,SEPT3,RRAS2,ATL1,RAB3B,RHOQ,TUBA1A,RAB6B,NUGGC,LRRK2,AK4,AGAP2,RAB38,GUCY1A2,GNAI1,RND3,GNAO1,GBP1,RAB31,DIRAS1,LRRK1,GEM,SEPT5,RAB30,GVINP1,RRAGD GO:0022889 serine transmembrane transporter activity 0.0496837040354984 -3.00207828625581 9 3 0.00178571428571429 1680 17224 256987,6510,347735 SERINC5,SLC1A5,SERINC2 GO:0004690 cyclic nucleotide-dependent protein kinase activity 0.0496837040354984 -3.00207828625581 9 3 0.00178571428571429 1680 17224 5593,5567,5592 PRKG2,PRKACB,PRKG1 GO:0015194 L-serine transmembrane transporter activity 0.0496837040354984 -3.00207828625581 9 3 0.00178571428571429 1680 17224 256987,6510,347735 SERINC5,SLC1A5,SERINC2 GO:0004656 procollagen-proline 4-dioxygenase activity 0.0499106742302366 -2.99752038667107 4 2 0.00119047619047619 1680 17224 5033,8974 P4HA1,P4HA2 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity 0.0499106742302366 -2.99752038667107 4 2 0.00119047619047619 1680 17224 337876,22856 CHSY3,CHSY1 GO:0003839 gamma-glutamylcyclotransferase activity 0.0499106742302366 -2.99752038667107 4 2 0.00119047619047619 1680 17224 79094,87769 CHAC1,GGACT GO:0004594 pantothenate kinase activity 0.0499106742302366 -2.99752038667107 4 2 0.00119047619047619 1680 17224 79646,53354 PANK3,PANK1 GO:0038085 vascular endothelial growth factor binding 0.0499106742302366 -2.99752038667107 4 2 0.00119047619047619 1680 17224 8829,5159 NRP1,PDGFRB GO:0003873 6-phosphofructo-2-kinase activity 0.0499106742302366 -2.99752038667107 4 2 0.00119047619047619 1680 17224 5210,5208 PFKFB4,PFKFB2 GO:0140135 mechanosensitive cation channel activity 0.0499106742302366 -2.99752038667107 4 2 0.00119047619047619 1680 17224 27112,728215 FAM155B,FAM155A GO:0004464 leukotriene-C4 synthase activity 0.0499106742302366 -2.99752038667107 4 2 0.00119047619047619 1680 17224 241,4259 ALOX5AP,MGST3 GO:0030060 L-malate dehydrogenase activity 0.0499106742302366 -2.99752038667107 4 2 0.00119047619047619 1680 17224 130752,26227 MDH1B,PHGDH GO:0005010 insulin-like growth factor-activated receptor activity 0.0499106742302366 -2.99752038667107 4 2 0.00119047619047619 1680 17224 3480,51232 IGF1R,CRIM1 GO:0016312 inositol bisphosphate phosphatase activity 0.0499106742302366 -2.99752038667107 4 2 0.00119047619047619 1680 17224 3628,8821 INPP1,INPP4B GO:0015093 ferrous iron transmembrane transporter activity 0.0499106742302366 -2.99752038667107 4 2 0.00119047619047619 1680 17224 23516,30061 SLC39A14,SLC40A1 GO:0031697 beta-1 adrenergic receptor binding 0.0499106742302366 -2.99752038667107 4 2 0.00119047619047619 1680 17224 9863,9693 MAGI2,RAPGEF2 GO:0016361 activin receptor activity, type I 0.0499106742302366 -2.99752038667107 4 2 0.00119047619047619 1680 17224 90,130399 ACVR1,ACVR1C GO:0004698 calcium-dependent protein kinase C activity 0.0499106742302366 -2.99752038667107 4 2 0.00119047619047619 1680 17224 5578,5579 PRKCA,PRKCB GO:0031698 beta-2 adrenergic receptor binding 0.0499106742302366 -2.99752038667107 4 2 0.00119047619047619 1680 17224 5144,4734 PDE4D,NEDD4 GO:0030229 very-low-density lipoprotein particle receptor activity 0.0499106742302366 -2.99752038667107 4 2 0.00119047619047619 1680 17224 3949,7436 LDLR,VLDLR GO:0031821 G-protein coupled serotonin receptor binding 0.0499106742302366 -2.99752038667107 4 2 0.00119047619047619 1680 17224 2775,2770 GNAO1,GNAI1 GO:0004634 phosphopyruvate hydratase activity 0.0499106742302366 -2.99752038667107 4 2 0.00119047619047619 1680 17224 2026,2023 ENO2,ENO1 GO:0016428 tRNA (cytosine-5-)-methyltransferase activity 0.0499106742302366 -2.99752038667107 4 2 0.00119047619047619 1680 17224 1787,221078 TRDMT1,NSUN6 GO:0047696 beta-adrenergic receptor kinase activity 0.0499106742302366 -2.99752038667107 4 2 0.00119047619047619 1680 17224 2870,157 GRK6,GRK3 GO:0030160 GKAP/Homer scaffold activity 0.0499106742302366 -2.99752038667107 4 2 0.00119047619047619 1680 17224 22941,9455 SHANK2,HOMER2 GO:0008453 alanine-glyoxylate transaminase activity 0.0499106742302366 -2.99752038667107 4 2 0.00119047619047619 1680 17224 85007,64850 PHYKPL,ETNPPL GO:0031685 adenosine receptor binding 0.0499106742302366 -2.99752038667107 4 2 0.00119047619047619 1680 17224 5028,54550 P2RY1,NECAB2 GO:0008144 drug binding 0.05047223515662 -2.98633189277446 1724 188 0.111904761904762 1680 17224 349565,4598,2180,90,3798,10396,445,18,5578,16,8428,51303,5891,11328,6196,51166,1768,54805,2051,5567,5159,2731,1545,10188,4139,10257,130399,120892,1244,93,4919,10110,157,9149,203,5167,10769,540,2081,5603,5287,144132,5563,833,7301,84706,55034,26524,860,6334,9748,284716,26038,116835,3480,57143,23461,10846,5592,112,80216,55137,375449,1131,4846,5058,2264,3048,4860,4651,11001,2194,6262,84033,55437,8476,55760,9261,57494,29941,3099,162394,79646,6296,2042,152110,4430,5596,4916,1147,2870,23046,780,91351,1592,10290,440,1138,83694,140469,92,22989,5144,4233,1767,3306,1491,2241,91807,2617,5163,5208,4597,53354,107,8973,5588,481,2444,79739,64850,57205,260425,2260,7453,27010,953,6999,5579,5754,84451,657,113612,5602,22983,23043,4642,8444,659,23464,57144,10079,338323,875,3800,3046,5028,5585,2047,3157,348751,5580,30845,2963,23678,59,6446,5593,85007,79659,4646,6850,55033,2242,490,5210,54795,26873,81788,205,4141,23250,79834,57761,2268,10000,5608,79858,138429,55605,3098,79705,129607,51776,23095,493,9619,478 NMNAT3,MVK,ACSL1,ACVR1,KIF5A,ATP8A1,ASS1,ABAT,PRKCA,AARS,STK24,FKBP11,MOK,FKBP9,RPS6KA2,AADAT,DNAH6,CNNM2,EPHB6,PRKACB,PDGFRB,GLDC,CYP1B1,TNK2,MARK1,ABCC4,ACVR1C,LRRK2,ABCC2,ACVR2B,ROR1,SGK2,GRK3,DYRK1B,AK1,ENPP1,PLK2,ATP7B,ERN1,MAPK13,PIK3C2B,DNHD1,PRKAA2,CARS,TYRO3,GPT2,MOCOS,LATS2,RUNX2,SCN8A,SLK,RIMKLA,CHD5,HSPA12B,IGF1R,ADCK1,ABCA5,PDE10A,PRKG1,ADCY6,ALPK1,FIGN,MAST4,CHRM3,NOS3,PAK1,FGFR4,HBG2,PNP,MYO10,SLC27A2,FASN,RYR2,OBSCN,STRADB,CDC42BPA,DHX32,MAPKAPK2,RIMKLB,PKN3,HK2,SLFN5,PANK3,ACSM3,EPHA3,NEK10,MYO1B,MAPK4,NTRK3,CHUK,GRK6,KIF21B,DDR1,DDX60L,CYP26A1,SPEG,ASNS,CHRNA5,RPS6KL1,MYO3B,ACVR2A,MYH15,PDE4D,MET,DNAH5,HSPA2,CTH,FER,MYLK3,GARS,PDK1,PFKFB2,MVD,PANK1,ADCY1,CHRNA6,PRKCQ,ATP1B1,FRK,TTLL7,ETNPPL,ATP10D,MAGI3,FGFR1,WARS,TPK1,ENTPD1,TDO2,PRKCB,PTK7,MAP3K21,BMPR1A,CYP2U1,MAPK10,MAST1,TNIK,MYO1D,DYRK3,BMPR2,GCAT,PAK5,ATP9A,NLRP14,CBS,KIF5C,HBE1,P2RY1,PKN1,EPHB1,HMGCS1,FTCDNL1,PRKCD,EHD3,GTF2F2,SGK3,ACTA2,SGK1,PRKG2,PHYKPL,DYNC2H1,MYO6,SYK,FKBP14,FES,ATP2B1,PFKFB4,TRPM4,OPLAH,NUAK2,AK4,MARS,ATP11A,PEAK1,TRIB3,FGR,AKT3,MAP2K6,NEK11,PIP5KL1,KIF21A,HK1,LRRK1,CMPK2,MAP3K20,KIF1B,ATP2B4,ABCG1,ATP1A3 GO:0015079 potassium ion transmembrane transporter activity 0.0508708891951983 -2.97846444054402 165 23 0.0136904761904762 1680 17224 27012,30818,3786,2898,285335,27133,3752,481,9990,3749,84679,3761,2900,219527,60598,27345,7881,3781,3755,27094,3790,9312,478 KCNV1,KCNIP3,KCNQ3,GRIK2,SLC9C1,KCNH5,KCND3,ATP1B1,SLC12A6,KCNC4,SLC9A7,KCNJ4,GRIK4,LRRC55,KCNK15,KCNMB4,KCNAB1,KCNN2,KCNG1,KCNMB3,KCNS3,KCNB2,ATP1A3 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity 0.0513522682100129 -2.96904617201518 15 4 0.00238095238095238 1680 17224 5151,5144,5153,10846 PDE8A,PDE4D,PDE1B,PDE10A GO:0008157 protein phosphatase 1 binding 0.0513522682100129 -2.96904617201518 15 4 0.00238095238095238 1680 17224 10859,116154,2241,55607 LILRB1,PHACTR3,FER,PPP1R9A GO:0001882 nucleoside binding 0.0530480308382366 -2.9365575335887 380 47 0.0279761904761905 1680 17224 92170,26052,9886,29984,54622,402,51175,65997,51655,122622,5881,10382,8153,1938,5911,23551,30845,25837,5106,379,5874,55964,22800,51062,5865,23433,7846,4860,51560,389643,120892,205,116986,23682,2977,2770,390,2775,2633,11031,148252,79705,2669,5413,27314,387751,58528 MTG1,DNM3,RHOBTB1,RHOD,ARL15,ARL2,TUBE1,RASL11B,RASD1,ADSSL1,RAC3,TUBB4A,RND2,EEF2,RAP2A,RASD2,EHD3,RAB26,PCK2,ARL4D,RAB27B,SEPT3,RRAS2,ATL1,RAB3B,RHOQ,TUBA1A,PNP,RAB6B,NUGGC,LRRK2,AK4,AGAP2,RAB38,GUCY1A2,GNAI1,RND3,GNAO1,GBP1,RAB31,DIRAS1,LRRK1,GEM,SEPT5,RAB30,GVINP1,RRAGD GO:0008013 beta-catenin binding 0.0535731464152448 -2.92670733616325 82 13 0.00773809523809524 1680 17224 4088,83439,5071,5829,5795,10076,51339,23426,25776,1000,8945,116931,1501 SMAD3,TCF7L1,PRKN,PXN,PTPRJ,PTPRU,DACT1,GRIP1,CBY1,CDH2,BTRC,MED12L,CTNND2 GO:0001883 purine nucleoside binding 0.0553023947446811 -2.89493906678602 372 46 0.0273809523809524 1680 17224 92170,26052,9886,29984,54622,402,51175,65997,51655,122622,5881,10382,8153,1938,5911,23551,30845,25837,5106,379,5874,55964,22800,51062,5865,23433,7846,51560,389643,120892,205,116986,23682,2977,2770,390,2775,2633,11031,148252,79705,2669,5413,27314,387751,58528 MTG1,DNM3,RHOBTB1,RHOD,ARL15,ARL2,TUBE1,RASL11B,RASD1,ADSSL1,RAC3,TUBB4A,RND2,EEF2,RAP2A,RASD2,EHD3,RAB26,PCK2,ARL4D,RAB27B,SEPT3,RRAS2,ATL1,RAB3B,RHOQ,TUBA1A,RAB6B,NUGGC,LRRK2,AK4,AGAP2,RAB38,GUCY1A2,GNAI1,RND3,GNAO1,GBP1,RAB31,DIRAS1,LRRK1,GEM,SEPT5,RAB30,GVINP1,RRAGD GO:1902936 phosphatidylinositol bisphosphate binding 0.0563888598621147 -2.87548366016307 99 15 0.00892857142857143 1680 17224 4139,115548,29091,54477,4430,3092,55353,59338,285590,134829,23236,5217,9846,1687,85477 MARK1,FCHO2,STXBP6,PLEKHA5,MYO1B,HIP1,LAPTM4B,PLEKHA1,SH3PXD2B,CLVS2,PLCB1,PFN2,GAB2,GSDME,SCIN GO:0033218 amide binding 0.0567344246451781 -2.86937411588203 309 39 0.0232142857142857 1680 17224 90,23621,3949,322,3843,1718,4481,10859,320,54103,348751,3480,590,25825,84570,2690,2947,5360,30061,2946,8322,84725,2948,2194,10203,51555,10333,2861,3839,1515,3673,8140,55353,5021,321,9536,4311,478,5125 ACVR1,BACE1,LDLR,APBB1,IPO5,DHCR24,MSR1,LILRB1,APBA1,GSAP,FTCDNL1,IGF1R,BCHE,BACE2,COL25A1,GHR,GSTM3,PLTP,SLC40A1,GSTM2,FZD4,PLEKHA8,GSTM4,FASN,CALCRL,PEX5L,TLR6,GPR37,KPNA3,CTSV,ITGA2,SLC7A5,LAPTM4B,OXTR,APBA2,PTGES,MME,ATP1A3,PCSK5 GO:0005158 insulin receptor binding 0.0567503747219883 -2.86909301961179 22 5 0.00297619047619048 1680 17224 8660,5167,2887,10580,3480 IRS2,ENPP1,GRB10,SORBS1,IGF1R GO:0032549 ribonucleoside binding 0.0573506003232212 -2.85857196775062 373 46 0.0273809523809524 1680 17224 92170,26052,9886,29984,54622,402,51175,65997,51655,122622,5881,10382,8153,1938,5911,23551,30845,25837,5106,379,5874,55964,22800,51062,5865,23433,7846,51560,389643,120892,205,116986,23682,2977,2770,390,2775,2633,11031,148252,79705,2669,5413,27314,387751,58528 MTG1,DNM3,RHOBTB1,RHOD,ARL15,ARL2,TUBE1,RASL11B,RASD1,ADSSL1,RAC3,TUBB4A,RND2,EEF2,RAP2A,RASD2,EHD3,RAB26,PCK2,ARL4D,RAB27B,SEPT3,RRAS2,ATL1,RAB3B,RHOQ,TUBA1A,RAB6B,NUGGC,LRRK2,AK4,AGAP2,RAB38,GUCY1A2,GNAI1,RND3,GNAO1,GBP1,RAB31,DIRAS1,LRRK1,GEM,SEPT5,RAB30,GVINP1,RRAGD GO:0140096 catalytic activity, acting on a protein 0.0589762418432717 -2.83062059679655 2313 247 0.14702380952381 1680 17224 90693,90,23321,1850,8492,11099,11174,6777,146664,5578,8428,2070,143279,51303,2152,81567,5891,22843,11328,114907,7049,6196,54504,3690,27143,2051,5521,114818,374378,5791,1363,5567,5159,10188,4139,130399,26249,151230,56062,120892,726,9829,8612,27351,93,8822,4919,2161,10110,79683,22838,157,9149,114088,10769,8974,2081,649,5603,8829,143384,5125,7301,5563,91694,26524,5789,26272,84959,9748,114805,55008,2122,2202,50862,220213,285671,2589,3480,57143,25825,8139,5592,119587,84171,80216,9443,25827,55137,375449,220441,2264,5058,5768,11282,84159,1944,1852,23127,7468,84033,55437,715,64409,64077,8476,283358,9261,4324,29941,9508,57161,54814,5799,126433,79845,64754,4311,2042,5071,685,152110,6768,9781,11226,720,79695,64131,84945,57520,5596,4916,11237,1147,2870,10584,780,9920,9372,10290,83852,56605,8555,399818,83694,64429,254887,140469,9805,92,64219,4233,57628,54961,25801,2241,2597,91807,5163,153830,10076,79875,27133,59336,5777,54941,5588,2444,79739,444,2260,254042,5903,89782,5795,60468,154214,5579,5754,360200,142679,5066,84451,5033,5802,3082,55819,657,401265,5602,57531,22983,23043,8444,10279,659,57144,90293,23621,51191,5585,2047,84749,26262,4734,80853,4245,5580,23678,10612,6446,5593,6850,55033,2242,5046,1843,5509,9099,10765,51232,5783,389643,158866,81788,7347,79623,79834,170691,5788,2591,64324,2268,138151,5352,5547,5608,10000,1515,79858,745,79705,51776,4325,8945,11285,7093 CCDC126,ACVR1,TRIM2,DUSP8,PRSS12,PTPN21,ADAMTS6,STAT5B,MGAT5B,PRKCA,STK24,EYA4,HECTD2,FKBP11,F3,TXNDC5,MOK,PPM1E,FKBP9,FBXO32,TGFBR3,RPS6KA2,CPVL,ITGB3,PALD1,EPHB6,PPP2R2B,KLHL29,GALNT18,PTPRE,CPE,PRKACB,PDGFRB,TNK2,MARK1,ACVR1C,KLHL3,KLHL23,KLHL4,LRRK2,CAPN5,DNAJC6,PLPP2,DESI1,ACVR2B,FGF17,ROR1,F12,SGK2,ZDHHC14,RNF44,GRK3,DYRK1B,TRIM9,PLK2,P4HA2,ERN1,BMP1,MAPK13,NRP1,CACUL1,PCSK5,TYRO3,PRKAA2,LONRF1,LATS2,PTPRD,FBXO4,UBASH3B,SLK,GALNT13,HERC6,MECOM,EFEMP1,RNF141,OTUD1,RNF180,GALNT1,IGF1R,ADCK1,BACE2,GAN,PRKG1,CPXM2,LOXL4,ALPK1,MED7,FBXL2,FIGN,MAST4,RNF152,FGFR4,PAK1,QSOX1,MGAT4B,ARID5B,EFNA3,DUSP9,COLGALT2,NSD2,OBSCN,STRADB,C1R,GALNT17,LHPP,CDC42BPA,B4GALNT3,MAPKAPK2,MMP15,PKN3,ADAMTS3,PELI2,QPCTL,PTPRN2,FBXO27,RNF122,SMYD3,MME,EPHA3,PRKN,BTC,NEK10,ST14,RNF144A,GALNT6,C4A,GALNT12,XYLT1,ABHD13,HECW2,MAPK4,NTRK3,RNF24,CHUK,GRK6,COLEC10,DDR1,KBTBD11,ZFYVE9,SPEG,SETDB2,ERO1B,CDC14B,EEF1AKMT2,RPS6KL1,ZDHHC6,ZDHHC23,MYO3B,SCRN1,ACVR2A,PJA1,MET,DPP10,SSH3,GCA,FER,GAPDH,MYLK3,PDK1,RNF145,PTPRU,THSD4,KCNH5,PRDM13,PTPN6,RNF125,PRKCQ,FRK,TTLL7,ASPH,FGFR1,METAP1D,RANBP2,LMLN,PTPRJ,BACH2,RNF217,PRKCB,PTK7,TMPRSS9,DUSP19,PAM,MAP3K21,P4HA1,PTPRS,HGF,RNF130,BMPR1A,KLHL31,MAPK10,HACE1,MAST1,TNIK,DYRK3,PRSS16,BMPR2,PAK5,KLHL13,BACE1,HERC5,PKN1,EPHB1,USP30,TSPAN17,NEDD4,KDM7A,MGAT1,PRKCD,SGK3,TRIM3,SGK1,PRKG2,SYK,FKBP14,FES,PCSK6,DUSP1,PPP1R3D,USP2,KDM5B,CRIM1,PTPN13,NUGGC,ZDHHC15,NUAK2,UCHL3,GALNT14,PEAK1,ADAMTS17,PTPRC,GALNT3,NSD1,FGR,NACC2,PLOD2,PRCP,MAP2K6,AKT3,CTSV,NEK11,MYRF,LRRK1,MAP3K20,MMP16,BTRC,B4GALT7,TLL2 GO:0001078 transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding 0.0597371210122518 -2.81780165931641 142 20 0.0119047619047619 1680 17224 11279,30818,122953,579,2625,467,639,23414,51222,53335,55509,4825,93986,1051,138151,7020,26137,2023,2672,6591 KLF8,KCNIP3,JDP2,NKX3-2,GATA3,ATF3,PRDM1,ZFPM2,ZNF219,BCL11A,BATF3,NKX6-1,FOXP2,CEBPB,NACC2,TFAP2A,ZBTB20,ENO1,GFI1,SNAI2 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen 0.0601134564672136 -2.81152156121837 44 8 0.00476190476190476 1680 17224 1595,9645,6307,8564,2329,6713,1592,4846 CYP51A1,MICAL2,MSMO1,KMO,FMO4,SQLE,CYP26A1,NOS3 GO:0034185 apolipoprotein binding 0.0633607401892627 -2.75891084926417 16 4 0.00238095238095238 1680 17224 4040,821,4038,7436 LRP6,CANX,LRP4,VLDLR GO:0070008 serine-type exopeptidase activity 0.0633607401892627 -2.75891084926417 16 4 0.00238095238095238 1680 17224 119587,54504,1363,5547 CPXM2,CPVL,CPE,PRCP GO:0005545 1-phosphatidylinositol binding 0.0633607401892627 -2.75891084926417 16 4 0.00238095238095238 1680 17224 51429,29887,9372,85477 SNX9,SNX10,ZFYVE9,SCIN GO:0003777 microtubule motor activity 0.0658135101828157 -2.72093013979924 118 17 0.0101190476190476 1680 17224 4642,4651,3798,4430,3800,23046,1780,1768,51626,140469,22989,55605,79659,144132,4646,1767,23095 MYO1D,MYO10,KIF5A,MYO1B,KIF5C,KIF21B,DYNC1I1,DNAH6,DYNC2LI1,MYO3B,MYH15,KIF21A,DYNC2H1,DNHD1,MYO6,DNAH5,KIF1B GO:0097001 ceramide binding 0.0659617333372309 -2.71868050302427 10 3 0.00178571428571429 1680 17224 55353,5360,84725 LAPTM4B,PLTP,PLEKHA8 GO:0008190 eukaryotic initiation factor 4E binding 0.0659617333372309 -2.71868050302427 10 3 0.00178571428571429 1680 17224 1978,23367,100127983 EIF4EBP1,LARP1,C8orf88 GO:0005072 transforming growth factor beta receptor, cytoplasmic mediator activity 0.0659617333372309 -2.71868050302427 10 3 0.00178571428571429 1680 17224 4088,4093,4091 SMAD3,SMAD9,SMAD6 GO:0034596 phosphatidylinositol phosphate 4-phosphatase activity 0.0659617333372309 -2.71868050302427 10 3 0.00178571428571429 1680 17224 22876,9896,8821 INPP5F,FIG4,INPP4B GO:0086080 protein binding involved in heterotypic cell-cell adhesion 0.0659617333372309 -2.71868050302427 10 3 0.00178571428571429 1680 17224 5318,1832,1829 PKP2,DSP,DSG2 GO:0035250 UDP-galactosyltransferase activity 0.0662262602708029 -2.71467821386838 30 6 0.00357142857142857 1680 17224 23127,7368,8708,11285,9331,8707 COLGALT2,UGT8,B3GALT1,B4GALT7,B4GALT6,B3GALT2 GO:0005227 calcium activated cation channel activity 0.0662262602708029 -2.71467821386838 30 6 0.00357142857142857 1680 17224 54795,55129,57156,27345,3781,27094 TRPM4,ANO10,TMEM63C,KCNMB4,KCNN2,KCNMB3 GO:0045503 dynein light chain binding 0.0669205116808605 -2.70424975673524 23 5 0.00297619047619048 1680 17224 79659,144132,1780,1767,1768 DYNC2H1,DNHD1,DYNC1I1,DNAH5,DNAH6 GO:0017134 fibroblast growth factor binding 0.0669205116808605 -2.70424975673524 23 5 0.00297619047619048 1680 17224 2264,6331,7049,2260,3690 FGFR4,SCN5A,TGFBR3,FGFR1,ITGB3 GO:0005248 voltage-gated sodium channel activity 0.0669205116808605 -2.70424975673524 23 5 0.00297619047619048 1680 17224 6331,6326,6324,6334,6328 SCN5A,SCN2A,SCN1B,SCN8A,SCN3A GO:0048037 cofactor binding 0.0697389902779053 -2.66299571621763 490 58 0.0345238095238095 1680 17224 84706,55034,55640,23464,1573,50865,1718,7358,285440,875,1488,3046,18,26227,1592,114112,1595,440,7881,8435,51166,8564,8614,2947,85007,83666,4846,3156,1545,2731,1491,9645,3048,217,2597,2946,7390,2948,51700,48,2194,55753,2977,64850,197257,5352,6999,8974,2329,56898,5066,3248,6713,5033,113612,1717,9536,51084 GPT2,MOCOS,FLVCR2,GCAT,CYP2J2,HEBP1,DHCR24,UGDH,CYP4V2,CBS,CTBP2,HBE1,ABAT,PHGDH,CYP26A1,TXNRD3,CYP51A1,ASNS,KCNAB1,SOAT2,AADAT,KMO,STC2,GSTM3,PHYKPL,PARP9,NOS3,HMGCR,CYP1B1,GLDC,CTH,MICAL2,HBG2,ALDH2,GAPDH,GSTM2,UROS,GSTM4,CYB5R2,ACO1,FASN,OGDHL,GUCY1A2,ETNPPL,LDHD,PLOD2,TDO2,P4HA2,FMO4,BDH2,PAM,HPGD,SQLE,P4HA1,CYP2U1,DHCR7,PTGES,CRYL1 GO:0015662 ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism 0.0716989643715119 -2.63527897539284 38 7 0.00416666666666667 1680 17224 90423,481,10257,540,493,490,478 ATP6V1E2,ATP1B1,ABCC4,ATP7B,ATP2B4,ATP2B1,ATP1A3 GO:0005267 potassium channel activity 0.0720955846216478 -2.62976247621073 128 18 0.0107142857142857 1680 17224 27012,30818,3786,2898,27133,3752,3749,3761,2900,219527,60598,27345,3781,7881,3755,27094,3790,9312 KCNV1,KCNIP3,KCNQ3,GRIK2,KCNH5,KCND3,KCNC4,KCNJ4,GRIK4,LRRC55,KCNK15,KCNMB4,KCNN2,KCNAB1,KCNG1,KCNMB3,KCNS3,KCNB2 GO:0015291 secondary active transmembrane transporter activity 0.0732790782220981 -2.61348013754229 243 31 0.018452380952381 1680 17224 6520,6536,54020,206358,285335,120103,114134,9990,6507,28232,84679,90550,55002,51310,23657,6567,5002,84879,84068,11182,8140,1015,81796,220963,154091,55117,353189,6510,85414,150159,117247 SLC3A2,SLC6A9,SLC37A1,SLC36A1,SLC9C1,SLC36A4,SLC2A13,SLC12A6,SLC1A3,SLCO3A1,SLC9A7,MCU,TMCO3,SLC22A17,SLC7A11,SLC16A2,SLC22A18,MFSD2A,SLC10A7,SLC2A6,SLC7A5,CDH17,SLCO5A1,SLC16A9,SLC2A12,SLC6A15,SLCO4C1,SLC1A5,SLC45A3,SLC9B1,SLC16A10 GO:0008083 growth factor activity 0.0733347267380626 -2.61272102050482 163 22 0.0130952380952381 1680 17224 7424,627,685,2258,2660,8838,7039,2257,50810,8822,654,22943,2202,3626,1890,10718,1435,7060,649,83729,3082,652 VEGFC,BDNF,BTC,FGF13,MSTN,WISP3,TGFA,FGF12,HDGFL3,FGF17,BMP6,DKK1,EFEMP1,INHBC,TYMP,NRG3,CSF1,THBS4,BMP1,INHBE,HGF,BMP4 GO:0045296 cadherin binding 0.0738502871231817 -2.60571538208838 325 40 0.0238095238095238 1680 17224 57530,3655,29091,9748,4430,5318,22837,7082,85456,51429,1496,8428,6164,4072,9531,1938,8496,153090,2017,4646,2023,114793,1627,90102,60437,6520,23670,26136,2194,10399,10458,55357,143098,226,54874,1000,23367,2810,57698,23348 CGN,ITGA6,STXBP6,SLK,MYO1B,PKP2,COBLL1,TJP1,TNKS1BP1,SNX9,CTNNA2,STK24,RPL34,EPCAM,BAG3,EEF2,PPFIBP1,DAB2IP,CTTN,MYO6,ENO1,FMNL2,DBN1,PHLDB2,CDH26,SLC3A2,CEMIP2,TES,FASN,RACK1,BAIAP2,TBC1D2,MPP7,ALDOA,FNBP1L,CDH2,LARP1,SFN,SHTN1,DOCK9 GO:0005080 protein kinase C binding 0.074653367139105 -2.59489965033292 46 8 0.00476190476190476 1680 17224 5579,51339,112,5318,10399,4082,5585,1832 PRKCB,DACT1,ADCY6,PKP2,RACK1,MARCKS,PKN1,DSP GO:0043565 sequence-specific DNA binding 0.0753620248155086 -2.58545178050401 1133 125 0.0744047619047619 1680 17224 64764,29842,5071,9658,5013,2625,6777,255877,1050,7227,64376,8320,29841,5462,1750,26468,604,5452,2115,2023,5455,6591,2735,7080,30818,468,4212,2649,11166,579,4774,4779,10413,100271849,467,23314,474,10538,53335,55509,4088,7552,9242,81931,83439,10781,22806,3131,60468,619279,54937,148523,688,1628,1746,10891,63973,3219,4306,29942,4208,23462,64919,11279,860,4601,55893,23051,5324,219749,5966,122953,51222,6304,2290,2122,4825,93986,253461,10265,126070,2624,4609,168620,6720,7020,8531,4091,148979,56033,1052,30062,4487,10765,3174,3164,2104,1112,84159,100289635,9516,9935,7468,639,3198,148156,7545,473,283078,1051,64324,5325,138151,7015,26508,7494,3239,745,5083,26257,6474,64754,10736,1649,3169 CREB3L2,TFCP2L1,PRKN,ZNF516,OTX1,GATA3,STAT5B,BCL6B,CEBPA,TRPS1,IKZF5,EOMES,GRHL1,POU5F1B,DLX6,LHX6,BCL6,POU2F2,ETV1,ENO1,POU3F3,SNAI2,GLI1,NKX2-1,KCNIP3,ATF4,MEIS2,NR6A1,SOX21,NKX3-2,NFIA,NFE2L1,YAP1,MEF2B,ATF3,SATB2,ATOH1,BATF,BCL11A,BATF3,SMAD3,ZNF711,MSC,ZNF93,TCF7L1,ZNF266,IKZF3,HLF,BACH2,ZNF704,SOHLH2,CIART,KLF5,DBP,DLX2,PPARGC1A,NEUROG2,HOXB9,NR3C2,PURG,MEF2C,HEY1,BCL11B,KLF8,RUNX2,MXI1,ZNF395,ZHX3,PLAG1,ZNF25,REL,JDP2,ZNF219,SATB1,FOXG1,MECOM,NKX6-1,FOXP2,ZBTB38,IRX5,ZNF440,GATA2,MYC,BHLHA15,SREBF1,TFAP2A,YBX3,SMAD6,GLIS1,BARX1,CEBPD,RAX,MSX1,KDM5B,HNF4G,NR4A1,ESRRG,FOXN3,ARID5B,ZNF605,LITAF,MAFB,NSD2,PRDM1,HOXA1,ZNF558,ZIC1,RERE,MKX,CEBPB,NSD1,PLAGL1,NACC2,TERT,HEYL,XBP1,HOXD13,MYRF,PAX9,NKX2-8,SHOX2,SMYD3,SIX2,DDIT3,FOXA1 GO:0098632 cell-cell adhesion mediator activity 0.0756466201854742 -2.58168251673889 31 6 0.00357142857142857 1680 17224 5318,4072,1832,29091,1829,10458 PKP2,EPCAM,DSP,STXBP6,DSG2,BAIAP2 GO:0046625 sphingolipid binding 0.0767009101854723 -2.5678417038544 17 4 0.00238095238095238 1680 17224 6402,55353,5360,84725 SELL,LAPTM4B,PLTP,PLEKHA8 GO:0030553 cGMP binding 0.0767009101854723 -2.5678417038544 17 4 0.00238095238095238 1680 17224 5593,10846,9693,5592 PRKG2,PDE10A,RAPGEF2,PRKG1 GO:0017081 chloride channel regulator activity 0.0767009101854723 -2.5678417038544 17 4 0.00238095238095238 1680 17224 6446,10110,8673,23678 SGK1,SGK2,VAMP8,SGK3 GO:0030228 lipoprotein particle receptor activity 0.0767009101854723 -2.5678417038544 17 4 0.00238095238095238 1680 17224 4040,3949,29967,7436 LRP6,LDLR,LRP12,VLDLR GO:0005005 transmembrane-ephrin receptor activity 0.0767009101854723 -2.5678417038544 17 4 0.00238095238095238 1680 17224 2042,2051,2047,1944 EPHA3,EPHB6,EPHB1,EFNA3 GO:0008823 cupric reductase activity 0.077875144135167 -2.55264845102337 5 2 0.00119047619047619 1680 17224 55240,26872 STEAP3,STEAP1 GO:0004331 fructose-2,6-bisphosphate 2-phosphatase activity 0.077875144135167 -2.55264845102337 5 2 0.00119047619047619 1680 17224 5210,5208 PFKFB4,PFKFB2 GO:0016715 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen 0.077875144135167 -2.55264845102337 5 2 0.00119047619047619 1680 17224 26002,5066 MOXD1,PAM GO:0038064 collagen receptor activity 0.077875144135167 -2.55264845102337 5 2 0.00119047619047619 1680 17224 780,3673 DDR1,ITGA2 GO:0015038 glutathione disulfide oxidoreductase activity 0.077875144135167 -2.55264845102337 5 2 0.00119047619047619 1680 17224 9446,119391 GSTO1,GSTO2 GO:0004396 hexokinase activity 0.077875144135167 -2.55264845102337 5 2 0.00119047619047619 1680 17224 3098,3099 HK1,HK2 GO:0042799 histone methyltransferase activity (H4-K20 specific) 0.077875144135167 -2.55264845102337 5 2 0.00119047619047619 1680 17224 7468,64324 NSD2,NSD1 GO:0038132 neuregulin binding 0.077875144135167 -2.55264845102337 5 2 0.00119047619047619 1680 17224 3655,3690 ITGA6,ITGB3 GO:0030023 extracellular matrix constituent conferring elasticity 0.077875144135167 -2.55264845102337 5 2 0.00119047619047619 1680 17224 2200,84034 FBN1,EMILIN2 GO:0019158 mannokinase activity 0.077875144135167 -2.55264845102337 5 2 0.00119047619047619 1680 17224 3098,3099 HK1,HK2 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer 0.077875144135167 -2.55264845102337 5 2 0.00119047619047619 1680 17224 3157,171425 HMGCS1,CLYBL GO:0052851 ferric-chelate reductase (NADPH) activity 0.077875144135167 -2.55264845102337 5 2 0.00119047619047619 1680 17224 55240,26872 STEAP3,STEAP1 GO:0015277 kainate selective glutamate receptor activity 0.077875144135167 -2.55264845102337 5 2 0.00119047619047619 1680 17224 2900,2898 GRIK4,GRIK2 GO:0005007 fibroblast growth factor-activated receptor activity 0.077875144135167 -2.55264845102337 5 2 0.00119047619047619 1680 17224 2264,2260 FGFR4,FGFR1 GO:0042392 sphingosine-1-phosphate phosphatase activity 0.077875144135167 -2.55264845102337 5 2 0.00119047619047619 1680 17224 8611,8612 PLPP1,PLPP2 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity 0.077875144135167 -2.55264845102337 5 2 0.00119047619047619 1680 17224 4088,4093 SMAD3,SMAD9 GO:0086007 voltage-gated calcium channel activity involved in cardiac muscle cell action potential 0.077875144135167 -2.55264845102337 5 2 0.00119047619047619 1680 17224 783,781 CACNB2,CACNA2D1 GO:0004340 glucokinase activity 0.077875144135167 -2.55264845102337 5 2 0.00119047619047619 1680 17224 3098,3099 HK1,HK2 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential 0.077875144135167 -2.55264845102337 5 2 0.00119047619047619 1680 17224 6331,6324 SCN5A,SCN1B GO:0017034 Rap guanyl-nucleotide exchange factor activity 0.077875144135167 -2.55264845102337 5 2 0.00119047619047619 1680 17224 9771,9693 RAPGEF5,RAPGEF2 GO:0047238 glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity 0.077875144135167 -2.55264845102337 5 2 0.00119047619047619 1680 17224 337876,22856 CHSY3,CHSY1 GO:0015349 thyroid hormone transmembrane transporter activity 0.077875144135167 -2.55264845102337 5 2 0.00119047619047619 1680 17224 6567,117247 SLC16A2,SLC16A10 GO:0016717 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water 0.077875144135167 -2.55264845102337 5 2 0.00119047619047619 1680 17224 3992,6319 FADS1,SCD GO:0008865 fructokinase activity 0.077875144135167 -2.55264845102337 5 2 0.00119047619047619 1680 17224 3098,3099 HK1,HK2 GO:0030159 receptor signaling complex scaffold activity 0.0780328875517271 -2.55062490587717 24 5 0.00297619047619048 1680 17224 23426,9863,22941,120892,9455 GRIP1,MAGI2,SHANK2,LRRK2,HOMER2 GO:0071889 14-3-3 protein binding 0.0780328875517271 -2.55062490587717 24 5 0.00297619047619048 1680 17224 8660,153090,171024,9750,54541 IRS2,DAB2IP,SYNPO2,RIPOR2,DDIT4 GO:0044390 ubiquitin-like protein conjugating enzyme binding 0.0803757421128528 -2.52104286333662 39 7 0.00416666666666667 1680 17224 54941,91694,285671,5071,154214,9781,23551 RNF125,LONRF1,RNF180,PRKN,RNF217,RNF144A,RASD2 GO:0035325 Toll-like receptor binding 0.0843269986205504 -2.47305319691535 11 3 0.00178571428571429 1680 17224 153090,10333,6850 DAB2IP,TLR6,SYK GO:0042577 lipid phosphatase activity 0.0843269986205504 -2.47305319691535 11 3 0.00178571428571429 1680 17224 8611,64748,8612 PLPP1,PLPPR2,PLPP2 GO:0042301 phosphate ion binding 0.0843269986205504 -2.47305319691535 11 3 0.00178571428571429 1680 17224 55970,4860,122622 GNG12,PNP,ADSSL1 GO:0005172 vascular endothelial growth factor receptor binding 0.0843269986205504 -2.47305319691535 11 3 0.00178571428571429 1680 17224 7424,153090,3690 VEGFC,DAB2IP,ITGB3 GO:0009931 calcium-dependent protein serine/threonine kinase activity 0.0843269986205504 -2.47305319691535 11 3 0.00178571428571429 1680 17224 9261,5578,5579 MAPKAPK2,PRKCA,PRKCB GO:0005381 iron ion transmembrane transporter activity 0.0843269986205504 -2.47305319691535 11 3 0.00178571428571429 1680 17224 23516,30061,81894 SLC39A14,SLC40A1,SLC25A28 GO:0042277 peptide binding 0.085436103152229 -2.45998651398373 274 34 0.0202380952380952 1680 17224 90,23621,3949,322,3843,1718,4481,10859,320,54103,3480,590,25825,84570,2690,2947,30061,2946,8322,2948,10203,51555,10333,2861,3839,3673,1515,8140,5021,321,9536,4311,5125,478 ACVR1,BACE1,LDLR,APBB1,IPO5,DHCR24,MSR1,LILRB1,APBA1,GSAP,IGF1R,BCHE,BACE2,COL25A1,GHR,GSTM3,SLC40A1,GSTM2,FZD4,GSTM4,CALCRL,PEX5L,TLR6,GPR37,KPNA3,ITGA2,CTSV,SLC7A5,OXTR,APBA2,PTGES,MME,PCSK5,ATP1A3 GO:0008201 heparin binding 0.0891875400594175 -2.41701393458563 158 21 0.0125 1680 17224 10178,2264,2335,3075,2660,8838,6402,2260,3627,7049,9508,2200,25890,84570,7060,5802,26577,652,8829,9353,5046 TENM1,FGFR4,FN1,CFH,MSTN,WISP3,SELL,FGFR1,CXCL10,TGFBR3,ADAMTS3,FBN1,ABI3BP,COL25A1,THBS4,PTPRS,PCOLCE2,BMP4,NRP1,SLIT2,PCSK6 GO:0030246 carbohydrate binding 0.0892411810536146 -2.4164126749288 266 33 0.0196428571428571 1680 17224 23324,9902,3958,79695,11226,6402,114805,821,10584,63827,2589,202,22859,26033,10960,178,374378,64409,1203,79623,131544,2591,5167,5352,8974,226,3099,5066,5033,3098,23266,285761,1272 MAN2B2,MRC2,LGALS3,GALNT12,GALNT6,SELL,GALNT13,CANX,COLEC10,BCAN,GALNT1,CRYBG1,ADGRL1,ATRNL1,LMAN2,AGL,GALNT18,GALNT17,CLN5,GALNT14,CRYBG3,GALNT3,ENPP1,PLOD2,P4HA2,ALDOA,HK2,PAM,P4HA1,HK1,ADGRL2,DCBLD1,CNTN1 GO:0098631 cell adhesion mediator activity 0.08963182851245 -2.41204479314652 40 7 0.00416666666666667 1680 17224 5318,4072,1832,29091,3673,10458,1829 PKP2,EPCAM,DSP,STXBP6,ITGA2,BAIAP2,DSG2 GO:0015295 solute:proton symporter activity 0.090069141180433 -2.40717766825545 25 5 0.00297619047619048 1680 17224 154091,114134,206358,85414,11182 SLC2A12,SLC2A13,SLC36A1,SLC45A3,SLC2A6 GO:0005402 carbohydrate:cation symporter activity 0.0913218911110469 -2.3933647489164 18 4 0.00238095238095238 1680 17224 154091,114134,85414,11182 SLC2A12,SLC2A13,SLC45A3,SLC2A6 GO:0035173 histone kinase activity 0.0913218911110469 -2.3933647489164 18 4 0.00238095238095238 1680 17224 5563,5578,5585,5579 PRKAA2,PRKCA,PKN1,PRKCB GO:0005524 ATP binding 0.0921176030611291 -2.38468922411275 1466 158 0.094047619047619 1680 17224 349565,4598,2180,90,3798,10396,445,5578,16,8428,5891,6196,1768,54805,2051,5567,5159,10188,4139,10257,130399,120892,1244,93,4919,10110,157,9149,203,5167,10769,540,2081,5603,5287,144132,5563,833,7301,26524,860,6334,9748,284716,26038,116835,3480,57143,23461,5592,112,80216,55137,375449,5058,2264,4651,11001,84033,55437,8476,55760,9261,57494,29941,3099,162394,79646,6296,2042,152110,4430,5596,4916,1147,2870,23046,780,91351,10290,440,83694,140469,92,22989,4233,1767,3306,2241,2617,91807,5163,5208,4597,53354,107,5588,481,2444,79739,57205,260425,2260,7453,27010,953,5579,5754,84451,657,5602,22983,4642,23043,8444,659,57144,10079,338323,3800,5028,5585,2047,5580,30845,2963,23678,59,6446,5593,79659,4646,6850,490,2242,5210,54795,26873,81788,205,4141,23250,79834,57761,2268,10000,5608,79858,138429,55605,79705,3098,129607,51776,23095,493,9619,478 NMNAT3,MVK,ACSL1,ACVR1,KIF5A,ATP8A1,ASS1,PRKCA,AARS,STK24,MOK,RPS6KA2,DNAH6,CNNM2,EPHB6,PRKACB,PDGFRB,TNK2,MARK1,ABCC4,ACVR1C,LRRK2,ABCC2,ACVR2B,ROR1,SGK2,GRK3,DYRK1B,AK1,ENPP1,PLK2,ATP7B,ERN1,MAPK13,PIK3C2B,DNHD1,PRKAA2,CARS,TYRO3,LATS2,RUNX2,SCN8A,SLK,RIMKLA,CHD5,HSPA12B,IGF1R,ADCK1,ABCA5,PRKG1,ADCY6,ALPK1,FIGN,MAST4,PAK1,FGFR4,MYO10,SLC27A2,OBSCN,STRADB,CDC42BPA,DHX32,MAPKAPK2,RIMKLB,PKN3,HK2,SLFN5,PANK3,ACSM3,EPHA3,NEK10,MYO1B,MAPK4,NTRK3,CHUK,GRK6,KIF21B,DDR1,DDX60L,SPEG,ASNS,RPS6KL1,MYO3B,ACVR2A,MYH15,MET,DNAH5,HSPA2,FER,GARS,MYLK3,PDK1,PFKFB2,MVD,PANK1,ADCY1,PRKCQ,ATP1B1,FRK,TTLL7,ATP10D,MAGI3,FGFR1,WARS,TPK1,ENTPD1,PRKCB,PTK7,MAP3K21,BMPR1A,MAPK10,MAST1,MYO1D,TNIK,DYRK3,BMPR2,PAK5,ATP9A,NLRP14,KIF5C,P2RY1,PKN1,EPHB1,PRKCD,EHD3,GTF2F2,SGK3,ACTA2,SGK1,PRKG2,DYNC2H1,MYO6,SYK,ATP2B1,FES,PFKFB4,TRPM4,OPLAH,NUAK2,AK4,MARS,ATP11A,PEAK1,TRIB3,FGR,AKT3,MAP2K6,NEK11,PIP5KL1,KIF21A,LRRK1,HK1,CMPK2,MAP3K20,KIF1B,ATP2B4,ABCG1,ATP1A3 GO:0015298 solute:cation antiporter activity 0.0966308318470318 -2.33685741842853 33 6 0.00357142857142857 1680 17224 55002,6520,285335,150159,5002,84679 TMCO3,SLC3A2,SLC9C1,SLC9B1,SLC22A18,SLC9A7 GO:0022843 voltage-gated cation channel activity 0.097037345698721 -2.3326593673717 142 19 0.0113095238095238 1680 17224 27012,10368,3786,777,27133,2621,3752,3749,785,23413,3761,219527,7881,783,3755,3790,2906,9312,781 KCNV1,CACNG3,KCNQ3,CACNA1E,KCNH5,GAS6,KCND3,KCNC4,CACNB4,NCS1,KCNJ4,LRRC55,KCNAB1,CACNB2,KCNG1,KCNS3,GRIN2D,KCNB2,CACNA2D1 GO:1904013 xenon atom binding 0.0975383186240023 -2.32750996665891 1 1 0.000595238095238095 1680 17224 10247 RIDA GO:0102867 molybdenum cofactor sulfurtransferase activity 0.0975383186240023 -2.32750996665891 1 1 0.000595238095238095 1680 17224 55034 MOCOS GO:0034211 GTP-dependent protein kinase activity 0.0975383186240023 -2.32750996665891 1 1 0.000595238095238095 1680 17224 120892 LRRK2 GO:0035605 peptidyl-cysteine S-nitrosylase activity 0.0975383186240023 -2.32750996665891 1 1 0.000595238095238095 1680 17224 2597 GAPDH GO:0061459 L-arginine transmembrane transporter activity 0.0975383186240023 -2.32750996665891 1 1 0.000595238095238095 1680 17224 6542 SLC7A2 GO:0003962 cystathionine gamma-synthase activity 0.0975383186240023 -2.32750996665891 1 1 0.000595238095238095 1680 17224 1491 CTH GO:0097626 low-affinity L-arginine transmembrane transporter activity 0.0975383186240023 -2.32750996665891 1 1 0.000595238095238095 1680 17224 6542 SLC7A2 GO:0050421 nitrite reductase (NO-forming) activity 0.0975383186240023 -2.32750996665891 1 1 0.000595238095238095 1680 17224 875 CBS GO:0031686 A1 adenosine receptor binding 0.0975383186240023 -2.32750996665891 1 1 0.000595238095238095 1680 17224 5028 P2RY1 GO:0015328 cystine secondary active transmembrane transporter activity 0.0975383186240023 -2.32750996665891 1 1 0.000595238095238095 1680 17224 23657 SLC7A11 GO:0086061 voltage-gated sodium channel activity involved in bundle of His cell action potential 0.0975383186240023 -2.32750996665891 1 1 0.000595238095238095 1680 17224 6331 SCN5A GO:0008405 arachidonic acid 11,12-epoxygenase activity 0.0975383186240023 -2.32750996665891 1 1 0.000595238095238095 1680 17224 1573 CYP2J2 GO:0008489 UDP-galactose:glucosylceramide beta-1,4-galactosyltransferase activity 0.0975383186240023 -2.32750996665891 1 1 0.000595238095238095 1680 17224 7368 UGT8 GO:0015067 amidinotransferase activity 0.0975383186240023 -2.32750996665891 1 1 0.000595238095238095 1680 17224 2628 GATM GO:0038021 leptin receptor activity 0.0975383186240023 -2.32750996665891 1 1 0.000595238095238095 1680 17224 3953 LEPR GO:0004617 phosphoglycerate dehydrogenase activity 0.0975383186240023 -2.32750996665891 1 1 0.000595238095238095 1680 17224 26227 PHGDH GO:0004133 glycogen debranching enzyme activity 0.0975383186240023 -2.32750996665891 1 1 0.000595238095238095 1680 17224 178 AGL GO:0042008 interleukin-18 receptor activity 0.0975383186240023 -2.32750996665891 1 1 0.000595238095238095 1680 17224 8809 IL18R1 GO:0004420 hydroxymethylglutaryl-CoA reductase (NADPH) activity 0.0975383186240023 -2.32750996665891 1 1 0.000595238095238095 1680 17224 3156 HMGCR GO:0070123 transforming growth factor beta receptor activity, type III 0.0975383186240023 -2.32750996665891 1 1 0.000595238095238095 1680 17224 7049 TGFBR3 GO:0016662 oxidoreductase activity, acting on other nitrogenous compounds as donors, cytochrome as acceptor 0.0975383186240023 -2.32750996665891 1 1 0.000595238095238095 1680 17224 875 CBS GO:0097689 iron channel activity 0.0975383186240023 -2.32750996665891 1 1 0.000595238095238095 1680 17224 30061 SLC40A1 GO:0045032 ADP-activated adenosine receptor activity 0.0975383186240023 -2.32750996665891 1 1 0.000595238095238095 1680 17224 5028 P2RY1 GO:0097627 high-affinity L-ornithine transmembrane transporter activity 0.0975383186240023 -2.32750996665891 1 1 0.000595238095238095 1680 17224 6542 SLC7A2 GO:1904012 platinum binding 0.0975383186240023 -2.32750996665891 1 1 0.000595238095238095 1680 17224 10247 RIDA GO:0047982 homocysteine desulfhydrase activity 0.0975383186240023 -2.32750996665891 1 1 0.000595238095238095 1680 17224 1491 CTH GO:0070856 myosin VI light chain binding 0.0975383186240023 -2.32750996665891 1 1 0.000595238095238095 1680 17224 128239 IQGAP3 GO:0042282 hydroxymethylglutaryl-CoA reductase activity 0.0975383186240023 -2.32750996665891 1 1 0.000595238095238095 1680 17224 3156 HMGCR GO:0086057 voltage-gated calcium channel activity involved in bundle of His cell action potential 0.0975383186240023 -2.32750996665891 1 1 0.000595238095238095 1680 17224 781 CACNA2D1 GO:0008890 glycine C-acetyltransferase activity 0.0975383186240023 -2.32750996665891 1 1 0.000595238095238095 1680 17224 23464 GCAT GO:0016232 HNK-1 sulfotransferase activity 0.0975383186240023 -2.32750996665891 1 1 0.000595238095238095 1680 17224 9486 CHST10 GO:0004496 mevalonate kinase activity 0.0975383186240023 -2.32750996665891 1 1 0.000595238095238095 1680 17224 4598 MVK GO:0008404 arachidonic acid 14,15-epoxygenase activity 0.0975383186240023 -2.32750996665891 1 1 0.000595238095238095 1680 17224 1573 CYP2J2 GO:0009918 sterol delta7 reductase activity 0.0975383186240023 -2.32750996665891 1 1 0.000595238095238095 1680 17224 1717 DHCR7 GO:0004506 squalene monooxygenase activity 0.0975383186240023 -2.32750996665891 1 1 0.000595238095238095 1680 17224 6713 SQLE GO:0047131 saccharopine dehydrogenase (NAD+, L-glutamate-forming) activity 0.0975383186240023 -2.32750996665891 1 1 0.000595238095238095 1680 17224 10157 AASS GO:0016642 oxidoreductase activity, acting on the CH-NH2 group of donors, disulfide as acceptor 0.0975383186240023 -2.32750996665891 1 1 0.000595238095238095 1680 17224 2731 GLDC GO:0033862 UMP kinase activity 0.0975383186240023 -2.32750996665891 1 1 0.000595238095238095 1680 17224 129607 CMPK2 GO:0015127 bilirubin transmembrane transporter activity 0.0975383186240023 -2.32750996665891 1 1 0.000595238095238095 1680 17224 1244 ABCC2 GO:0047117 enoyl-[acyl-carrier-protein] reductase (NADPH, A-specific) activity 0.0975383186240023 -2.32750996665891 1 1 0.000595238095238095 1680 17224 2194 FASN GO:0047263 N-acylsphingosine galactosyltransferase activity 0.0975383186240023 -2.32750996665891 1 1 0.000595238095238095 1680 17224 7368 UGT8 GO:0047369 succinate-hydroxymethylglutarate CoA-transferase activity 0.0975383186240023 -2.32750996665891 1 1 0.000595238095238095 1680 17224 79783 SUGCT GO:0102279 lecithin:11-cis retinol acyltransferase activity 0.0975383186240023 -2.32750996665891 1 1 0.000595238095238095 1680 17224 9227 LRAT GO:0004990 oxytocin receptor activity 0.0975383186240023 -2.32750996665891 1 1 0.000595238095238095 1680 17224 5021 OXTR GO:0018738 S-formylglutathione hydrolase activity 0.0975383186240023 -2.32750996665891 1 1 0.000595238095238095 1680 17224 2098 ESD GO:0019171 3-hydroxyacyl-[acyl-carrier-protein] dehydratase activity 0.0975383186240023 -2.32750996665891 1 1 0.000595238095238095 1680 17224 2194 FASN GO:0043914 NADPH:sulfur oxidoreductase activity 0.0975383186240023 -2.32750996665891 1 1 0.000595238095238095 1680 17224 9645 MICAL2 GO:0047390 glycerophosphocholine cholinephosphodiesterase activity 0.0975383186240023 -2.32750996665891 1 1 0.000595238095238095 1680 17224 133121 ENPP6 GO:0086063 voltage-gated sodium channel activity involved in SA node cell action potential 0.0975383186240023 -2.32750996665891 1 1 0.000595238095238095 1680 17224 6331 SCN5A GO:0004055 argininosuccinate synthase activity 0.0975383186240023 -2.32750996665891 1 1 0.000595238095238095 1680 17224 445 ASS1 GO:0005366 myo-inositol:proton symporter activity 0.0975383186240023 -2.32750996665891 1 1 0.000595238095238095 1680 17224 114134 SLC2A13 GO:0047464 heparosan-N-sulfate-glucuronate 5-epimerase activity 0.0975383186240023 -2.32750996665891 1 1 0.000595238095238095 1680 17224 26035 GLCE GO:0004504 peptidylglycine monooxygenase activity 0.0975383186240023 -2.32750996665891 1 1 0.000595238095238095 1680 17224 5066 PAM GO:0016872 intramolecular lyase activity 0.0975383186240023 -2.32750996665891 1 1 0.000595238095238095 1680 17224 51477 ISYNA1 GO:0102389 polyprenol reductase activity 0.0975383186240023 -2.32750996665891 1 1 0.000595238095238095 1680 17224 79644 SRD5A3 GO:0050459 ethanolamine-phosphate phospho-lyase activity 0.0975383186240023 -2.32750996665891 1 1 0.000595238095238095 1680 17224 64850 ETNPPL GO:0004940 beta1-adrenergic receptor activity 0.0975383186240023 -2.32750996665891 1 1 0.000595238095238095 1680 17224 153 ADRB1 GO:0050480 imidazolonepropionase activity 0.0975383186240023 -2.32750996665891 1 1 0.000595238095238095 1680 17224 144193 AMDHD1 GO:0036479 peroxidase inhibitor activity 0.0975383186240023 -2.32750996665891 1 1 0.000595238095238095 1680 17224 120892 LRRK2 GO:0004753 saccharopine dehydrogenase activity 0.0975383186240023 -2.32750996665891 1 1 0.000595238095238095 1680 17224 10157 AASS GO:0003979 UDP-glucose 6-dehydrogenase activity 0.0975383186240023 -2.32750996665891 1 1 0.000595238095238095 1680 17224 7358 UGDH GO:0047933 glucose-1,6-bisphosphate synthase activity 0.0975383186240023 -2.32750996665891 1 1 0.000595238095238095 1680 17224 283209 PGM2L1 GO:0004123 cystathionine gamma-lyase activity 0.0975383186240023 -2.32750996665891 1 1 0.000595238095238095 1680 17224 1491 CTH GO:0034386 4-aminobutyrate:2-oxoglutarate transaminase activity 0.0975383186240023 -2.32750996665891 1 1 0.000595238095238095 1680 17224 18 ABAT GO:0033608 formyl-CoA transferase activity 0.0975383186240023 -2.32750996665891 1 1 0.000595238095238095 1680 17224 79783 SUGCT GO:0008265 Mo-molybdopterin cofactor sulfurase activity 0.0975383186240023 -2.32750996665891 1 1 0.000595238095238095 1680 17224 55034 MOCOS GO:0030975 thiamine binding 0.0975383186240023 -2.32750996665891 1 1 0.000595238095238095 1680 17224 27010 TPK1 GO:0097625 low-affinity basic amino acid transmembrane transporter activity 0.0975383186240023 -2.32750996665891 1 1 0.000595238095238095 1680 17224 6542 SLC7A2 GO:0050614 delta24-sterol reductase activity 0.0975383186240023 -2.32750996665891 1 1 0.000595238095238095 1680 17224 1718 DHCR24 GO:0004135 amylo-alpha-1,6-glucosidase activity 0.0975383186240023 -2.32750996665891 1 1 0.000595238095238095 1680 17224 178 AGL GO:0000246 delta24(24-1) sterol reductase activity 0.0975383186240023 -2.32750996665891 1 1 0.000595238095238095 1680 17224 1718 DHCR24 GO:0044540 L-cystine L-cysteine-lyase (deaminating) 0.0975383186240023 -2.32750996665891 1 1 0.000595238095238095 1680 17224 1491 CTH GO:0031721 hemoglobin alpha binding 0.0975383186240023 -2.32750996665891 1 1 0.000595238095238095 1680 17224 3046 HBE1 GO:0051978 lysophospholipid transporter activity 0.0975383186240023 -2.32750996665891 1 1 0.000595238095238095 1680 17224 84879 MFSD2A GO:0047173 phosphatidylcholine-retinol O-acyltransferase activity 0.0975383186240023 -2.32750996665891 1 1 0.000595238095238095 1680 17224 9227 LRAT GO:0004608 phosphatidylethanolamine N-methyltransferase activity 0.0975383186240023 -2.32750996665891 1 1 0.000595238095238095 1680 17224 10400 PEMT GO:0102131 3-oxo-glutaryl-[acp] methyl ester reductase activity 0.0975383186240023 -2.32750996665891 1 1 0.000595238095238095 1680 17224 2194 FASN GO:0060961 phospholipase D inhibitor activity 0.0975383186240023 -2.32750996665891 1 1 0.000595238095238095 1680 17224 6622 SNCA GO:0004122 cystathionine beta-synthase activity 0.0975383186240023 -2.32750996665891 1 1 0.000595238095238095 1680 17224 875 CBS GO:0004512 inositol-3-phosphate synthase activity 0.0975383186240023 -2.32750996665891 1 1 0.000595238095238095 1680 17224 51477 ISYNA1 GO:0086060 voltage-gated sodium channel activity involved in AV node cell action potential 0.0975383186240023 -2.32750996665891 1 1 0.000595238095238095 1680 17224 6331 SCN5A GO:0008496 mannan endo-1,6-alpha-mannosidase activity 0.0975383186240023 -2.32750996665891 1 1 0.000595238095238095 1680 17224 23324 MAN2B2 GO:0070251 pristanate-CoA ligase activity 0.0975383186240023 -2.32750996665891 1 1 0.000595238095238095 1680 17224 11001 SLC27A2 GO:0004134 4-alpha-glucanotransferase activity 0.0975383186240023 -2.32750996665891 1 1 0.000595238095238095 1680 17224 178 AGL GO:0004502 kynurenine 3-monooxygenase activity 0.0975383186240023 -2.32750996665891 1 1 0.000595238095238095 1680 17224 8564 KMO GO:0004441 inositol-1,4-bisphosphate 1-phosphatase activity 0.0975383186240023 -2.32750996665891 1 1 0.000595238095238095 1680 17224 3628 INPP1 GO:0000210 NAD+ diphosphatase activity 0.0975383186240023 -2.32750996665891 1 1 0.000595238095238095 1680 17224 83594 NUDT12 GO:0102132 3-oxo-pimeloyl-[acp] methyl ester reductase activity 0.0975383186240023 -2.32750996665891 1 1 0.000595238095238095 1680 17224 2194 FASN GO:0004598 peptidylamidoglycolate lyase activity 0.0975383186240023 -2.32750996665891 1 1 0.000595238095238095 1680 17224 5066 PAM GO:0004163 diphosphomevalonate decarboxylase activity 0.0975383186240023 -2.32750996665891 1 1 0.000595238095238095 1680 17224 4597 MVD GO:1901680 sulfur-containing amino acid secondary active transmembrane transporter activity 0.0975383186240023 -2.32750996665891 1 1 0.000595238095238095 1680 17224 23657 SLC7A11 GO:0061929 gamma-glutamylaminecyclotransferase activity 0.0975383186240023 -2.32750996665891 1 1 0.000595238095238095 1680 17224 87769 GGACT GO:0004852 uroporphyrinogen-III synthase activity 0.0975383186240023 -2.32750996665891 1 1 0.000595238095238095 1680 17224 7390 UROS GO:0047598 7-dehydrocholesterol reductase activity 0.0975383186240023 -2.32750996665891 1 1 0.000595238095238095 1680 17224 1717 DHCR7 GO:0070025 carbon monoxide binding 0.0975383186240023 -2.32750996665891 1 1 0.000595238095238095 1680 17224 875 CBS GO:0004377 GDP-Man:Man3GlcNAc2-PP-Dol alpha-1,2-mannosyltransferase activity 0.0975383186240023 -2.32750996665891 1 1 0.000595238095238095 1680 17224 440138 ALG11 GO:0008267 poly-glutamine tract binding 0.0975383186240023 -2.32750996665891 1 1 0.000595238095238095 1680 17224 473 RERE GO:0080146 L-cysteine desulfhydrase activity 0.0975383186240023 -2.32750996665891 1 1 0.000595238095238095 1680 17224 1491 CTH GO:0008460 dTDP-glucose 4,6-dehydratase activity 0.0975383186240023 -2.32750996665891 1 1 0.000595238095238095 1680 17224 23483 TGDS GO:0017168 5-oxoprolinase (ATP-hydrolyzing) activity 0.0975383186240023 -2.32750996665891 1 1 0.000595238095238095 1680 17224 26873 OPLAH GO:0015196 L-tryptophan transmembrane transporter activity 0.0975383186240023 -2.32750996665891 1 1 0.000595238095238095 1680 17224 120103 SLC36A4 GO:0005008 hepatocyte growth factor-activated receptor activity 0.0975383186240023 -2.32750996665891 1 1 0.000595238095238095 1680 17224 4233 MET GO:0102500 beta-maltose 4-alpha-glucanotransferase activity 0.0975383186240023 -2.32750996665891 1 1 0.000595238095238095 1680 17224 178 AGL GO:0004597 peptide-aspartate beta-dioxygenase activity 0.0975383186240023 -2.32750996665891 1 1 0.000595238095238095 1680 17224 444 ASPH GO:1901707 leptomycin B binding 0.0975383186240023 -2.32750996665891 1 1 0.000595238095238095 1680 17224 3399 ID3 GO:0004375 glycine dehydrogenase (decarboxylating) activity 0.0975383186240023 -2.32750996665891 1 1 0.000595238095238095 1680 17224 2731 GLDC GO:0031687 A2A adenosine receptor binding 0.0975383186240023 -2.32750996665891 1 1 0.000595238095238095 1680 17224 54550 NECAB2 GO:0071614 linoleic acid epoxygenase activity 0.0975383186240023 -2.32750996665891 1 1 0.000595238095238095 1680 17224 1573 CYP2J2 GO:0060001 minus-end directed microfilament motor activity 0.0975383186240023 -2.32750996665891 1 1 0.000595238095238095 1680 17224 4646 MYO6 GO:0047277 globoside alpha-N-acetylgalactosaminyltransferase activity 0.0975383186240023 -2.32750996665891 1 1 0.000595238095238095 1680 17224 26301 GBGT1 GO:0004919 interleukin-9 receptor activity 0.0975383186240023 -2.32750996665891 1 1 0.000595238095238095 1680 17224 3581 IL9R GO:0052829 inositol-1,3,4-trisphosphate 1-phosphatase activity 0.0975383186240023 -2.32750996665891 1 1 0.000595238095238095 1680 17224 3628 INPP1 GO:0050104 L-gulonate 3-dehydrogenase activity 0.0975383186240023 -2.32750996665891 1 1 0.000595238095238095 1680 17224 51084 CRYL1 GO:0042602 riboflavin reductase (NADPH) activity 0.0975383186240023 -2.32750996665891 1 1 0.000595238095238095 1680 17224 645 BLVRB GO:0015327 cystine:glutamate antiporter activity 0.0975383186240023 -2.32750996665891 1 1 0.000595238095238095 1680 17224 23657 SLC7A11 GO:0003867 4-aminobutyrate transaminase activity 0.0975383186240023 -2.32750996665891 1 1 0.000595238095238095 1680 17224 18 ABAT GO:0016154 pyrimidine-nucleoside phosphorylase activity 0.0975383186240023 -2.32750996665891 1 1 0.000595238095238095 1680 17224 1890 TYMP GO:0008579 JUN kinase phosphatase activity 0.0975383186240023 -2.32750996665891 1 1 0.000595238095238095 1680 17224 142679 DUSP19 GO:0072591 citrate-L-glutamate ligase activity 0.0975383186240023 -2.32750996665891 1 1 0.000595238095238095 1680 17224 57494 RIMKLB GO:0047451 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity 0.0975383186240023 -2.32750996665891 1 1 0.000595238095238095 1680 17224 2194 FASN GO:0030107 HLA-A specific inhibitory MHC class I receptor activity 0.0975383186240023 -2.32750996665891 1 1 0.000595238095238095 1680 17224 10859 LILRB1 GO:0047777 (3S)-citramalyl-CoA lyase activity 0.0975383186240023 -2.32750996665891 1 1 0.000595238095238095 1680 17224 171425 CLYBL GO:0004621 glycosylphosphatidylinositol phospholipase D activity 0.0975383186240023 -2.32750996665891 1 1 0.000595238095238095 1680 17224 2822 GPLD1 GO:1990444 F-box domain binding 0.0975383186240023 -2.32750996665891 1 1 0.000595238095238095 1680 17224 5071 PRKN GO:0004788 thiamine diphosphokinase activity 0.0975383186240023 -2.32750996665891 1 1 0.000595238095238095 1680 17224 27010 TPK1 GO:0031962 mineralocorticoid receptor binding 0.0975383186240023 -2.32750996665891 1 1 0.000595238095238095 1680 17224 4088 SMAD3 GO:0004474 malate synthase activity 0.0975383186240023 -2.32750996665891 1 1 0.000595238095238095 1680 17224 171425 CLYBL GO:0046525 xylosylprotein 4-beta-galactosyltransferase activity 0.0975383186240023 -2.32750996665891 1 1 0.000595238095238095 1680 17224 11285 B4GALT7 GO:0047298 (S)-3-amino-2-methylpropionate transaminase activity 0.0975383186240023 -2.32750996665891 1 1 0.000595238095238095 1680 17224 18 ABAT GO:0072570 ADP-D-ribose binding 0.0975383186240023 -2.32750996665891 1 1 0.000595238095238095 1680 17224 83666 PARP9 GO:0098809 nitrite reductase activity 0.0975383186240023 -2.32750996665891 1 1 0.000595238095238095 1680 17224 875 CBS GO:0008398 sterol 14-demethylase activity 0.0975383186240023 -2.32750996665891 1 1 0.000595238095238095 1680 17224 1595 CYP51A1 GO:0000773 phosphatidyl-N-methylethanolamine N-methyltransferase activity 0.0975383186240023 -2.32750996665891 1 1 0.000595238095238095 1680 17224 10400 PEMT GO:0032145 succinate-semialdehyde dehydrogenase binding 0.0975383186240023 -2.32750996665891 1 1 0.000595238095238095 1680 17224 18 ABAT GO:0015068 glycine amidinotransferase activity 0.0975383186240023 -2.32750996665891 1 1 0.000595238095238095 1680 17224 2628 GATM GO:0070280 pyridoxal binding 0.0975383186240023 -2.32750996665891 1 1 0.000595238095238095 1680 17224 2731 GLDC GO:0009032 thymidine phosphorylase activity 0.0975383186240023 -2.32750996665891 1 1 0.000595238095238095 1680 17224 1890 TYMP GO:0098633 collagen fibril binding 0.0975383186240023 -2.32750996665891 1 1 0.000595238095238095 1680 17224 150356 CHADL GO:0047130 saccharopine dehydrogenase (NADP+, L-lysine-forming) activity 0.0975383186240023 -2.32750996665891 1 1 0.000595238095238095 1680 17224 10157 AASS GO:0008859 exoribonuclease II activity 0.0975383186240023 -2.32750996665891 1 1 0.000595238095238095 1680 17224 3669 ISG20 GO:0036487 nitric-oxide synthase inhibitor activity 0.0975383186240023 -2.32750996665891 1 1 0.000595238095238095 1680 17224 493 ATP2B4 GO:0050197 phytanate-CoA ligase activity 0.0975383186240023 -2.32750996665891 1 1 0.000595238095238095 1680 17224 11001 SLC27A2 GO:0050683 AF-1 domain binding 0.0975383186240023 -2.32750996665891 1 1 0.000595238095238095 1680 17224 26508 HEYL GO:0003908 methylated-DNA-[protein]-cysteine S-methyltransferase activity 0.0975383186240023 -2.32750996665891 1 1 0.000595238095238095 1680 17224 4255 MGMT GO:0004313 [acyl-carrier-protein] S-acetyltransferase activity 0.0975383186240023 -2.32750996665891 1 1 0.000595238095238095 1680 17224 2194 FASN GO:0047992 hydroxylysine kinase activity 0.0975383186240023 -2.32750996665891 1 1 0.000595238095238095 1680 17224 123688 HYKK GO:0005294 neutral L-amino acid secondary active transmembrane transporter activity 0.0975383186240023 -2.32750996665891 1 1 0.000595238095238095 1680 17224 23657 SLC7A11 GO:0043924 suramin binding 0.0975383186240023 -2.32750996665891 1 1 0.000595238095238095 1680 17224 6262 RYR2 GO:1990699 palmitoleyl hydrolase activity 0.0975383186240023 -2.32750996665891 1 1 0.000595238095238095 1680 17224 147111 NOTUM GO:0004316 3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity 0.0975383186240023 -2.32750996665891 1 1 0.000595238095238095 1680 17224 2194 FASN GO:0047536 2-aminoadipate transaminase activity 0.0975383186240023 -2.32750996665891 1 1 0.000595238095238095 1680 17224 51166 AADAT GO:0045485 omega-6 fatty acid desaturase activity 0.0975383186240023 -2.32750996665891 1 1 0.000595238095238095 1680 17224 3992 FADS1 GO:0080101 phosphatidyl-N-dimethylethanolamine N-methyltransferase activity 0.0975383186240023 -2.32750996665891 1 1 0.000595238095238095 1680 17224 10400 PEMT GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups 0.0978298111790923 -2.32452593060674 65 10 0.00595238095238095 1680 17224 54332,2946,241,119391,4259,2948,2947,9446,9536,1491 GDAP1,GSTM2,ALOX5AP,GSTO2,MGST3,GSTM4,GSTM3,GSTO1,PTGES,CTH GO:0046943 carboxylic acid transmembrane transporter activity 0.0985213213387976 -2.31748229393588 160 21 0.0125 1680 17224 256987,6520,6536,206358,11001,120103,1244,6507,6542,10560,6541,23657,6567,84879,8140,347735,220963,55117,6510,117247,8501 SERINC5,SLC3A2,SLC6A9,SLC36A1,SLC27A2,SLC36A4,ABCC2,SLC1A3,SLC7A2,SLC19A2,SLC7A1,SLC7A11,SLC16A2,MFSD2A,SLC7A5,SERINC2,SLC16A9,SLC6A15,SLC1A5,SLC16A10,SLC43A1 GO:0005342 organic acid transmembrane transporter activity 0.0985213213387976 -2.31748229393588 160 21 0.0125 1680 17224 256987,6520,6536,206358,11001,120103,1244,6507,6542,10560,6541,23657,6567,84879,8140,347735,220963,55117,6510,117247,8501 SERINC5,SLC3A2,SLC6A9,SLC36A1,SLC27A2,SLC36A4,ABCC2,SLC1A3,SLC7A2,SLC19A2,SLC7A1,SLC7A11,SLC16A2,MFSD2A,SLC7A5,SERINC2,SLC16A9,SLC6A15,SLC1A5,SLC16A10,SLC43A1 GO:0046915 transition metal ion transmembrane transporter activity 0.0994611605977161 -2.30798805677392 41 7 0.00416666666666667 1680 17224 23516,30061,81894,7782,64116,540,475 SLC39A14,SLC40A1,SLC25A28,SLC30A4,SLC39A8,ATP7B,ATOX1 GO:0016776 phosphotransferase activity, phosphate group as acceptor 0.0994611605977161 -2.30798805677392 41 7 0.00416666666666667 1680 17224 205,203,1740,129607,4354,260425,4355 AK4,AK1,DLG2,CMPK2,MPP1,MAGI3,MPP2 GO:0019210 kinase inhibitor activity 0.0999127312228982 -2.30345816177872 99 14 0.00833333333333333 1680 17224 55450,57761,5611,23767,142679,4040,4869,5577,10399,10253,54997,2810,5569,7453 CAMK2N1,TRIB3,DNAJC3,FLRT3,DUSP19,LRP6,NPM1,PRKAR2B,RACK1,SPRY2,TESC,SFN,PKIA,WARS GO:0005200 structural constituent of cytoskeleton 0.102271687012926 -2.28012240862288 108 15 0.00892857142857143 1680 17224 57669,10382,23136,7846,287,3092,51175,5357,7431,10174,7168,83660,1832,1496,84978 EPB41L5,TUBB4A,EPB41L3,TUBA1A,ANK2,HIP1,TUBE1,PLS1,VIM,SORBS3,TPM1,TLN2,DSP,CTNNA2,FRMD5 GO:0030507 spectrin binding 0.103002534410982 -2.27300168512336 26 5 0.00297619047619048 1680 17224 119,1780,4651,287,2633 ADD2,DYNC1I1,MYO10,ANK2,GBP1 GO:0070273 phosphatidylinositol-4-phosphate binding 0.103002534410982 -2.27300168512336 26 5 0.00297619047619048 1680 17224 153090,285590,84725,54477,114879 DAB2IP,SH3PXD2B,PLEKHA8,PLEKHA5,OSBPL5 GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen 0.103413781037617 -2.26901704689487 161 21 0.0125 1680 17224 3992,9645,1573,285440,6319,444,1592,1595,80853,6307,8564,5352,8974,2329,5066,6713,5033,113612,26002,1545,4846 FADS1,MICAL2,CYP2J2,CYP4V2,SCD,ASPH,CYP26A1,CYP51A1,KDM7A,MSMO1,KMO,PLOD2,P4HA2,FMO4,PAM,SQLE,P4HA1,CYP2U1,MOXD1,CYP1B1,NOS3 GO:0010857 calcium-dependent protein kinase activity 0.104586559387869 -2.2577402309434 12 3 0.00178571428571429 1680 17224 9261,5578,5579 MAPKAPK2,PRKCA,PRKCB GO:0030898 actin-dependent ATPase activity 0.104586559387869 -2.2577402309434 12 3 0.00178571428571429 1680 17224 4642,4651,4430 MYO1D,MYO10,MYO1B GO:0008331 high voltage-gated calcium channel activity 0.104586559387869 -2.2577402309434 12 3 0.00178571428571429 1680 17224 785,783,777 CACNB4,CACNB2,CACNA1E GO:0038191 neuropilin binding 0.107158029699229 -2.23345062100678 19 4 0.00238095238095238 1680 17224 10512,5829,10505,10371 SEMA3C,PXN,SEMA4F,SEMA3A GO:0034237 protein kinase A regulatory subunit binding 0.107158029699229 -2.23345062100678 19 4 0.00238095238095238 1680 17224 6262,84281,9465,9495 RYR2,C2orf88,AKAP7,AKAP5 GO:0005234 extracellularly glutamate-gated ion channel activity 0.107158029699229 -2.23345062100678 19 4 0.00238095238095238 1680 17224 2906,2900,2898,2894 GRIN2D,GRIK4,GRIK2,GRID1 GO:0004970 ionotropic glutamate receptor activity 0.107158029699229 -2.23345062100678 19 4 0.00238095238095238 1680 17224 2906,2900,2898,2894 GRIN2D,GRIK4,GRIK2,GRID1 GO:0043395 heparan sulfate proteoglycan binding 0.107158029699229 -2.23345062100678 19 4 0.00238095238095238 1680 17224 5802,3075,10082,3673 PTPRS,CFH,GPC6,ITGA2 GO:0052745 inositol phosphate phosphatase activity 0.107158029699229 -2.23345062100678 19 4 0.00238095238095238 1680 17224 22876,3636,3628,8821 INPP5F,INPPL1,INPP1,INPP4B GO:0005539 glycosaminoglycan binding 0.107561201309302 -2.2296952789073 216 27 0.0160714285714286 1680 17224 10178,2264,50512,2335,3075,2660,23670,8838,6402,3512,63827,2260,3627,7049,9508,2200,25890,84570,7060,5802,3098,26577,652,8829,9353,50859,5046 TENM1,FGFR4,PODXL2,FN1,CFH,MSTN,CEMIP2,WISP3,SELL,JCHAIN,BCAN,FGFR1,CXCL10,TGFBR3,ADAMTS3,FBN1,ABI3BP,COL25A1,THBS4,PTPRS,HK1,PCOLCE2,BMP4,NRP1,SLIT2,SPOCK3,PCSK6 GO:0030346 protein phosphatase 2B binding 0.109424292374946 -2.21252236268463 6 2 0.00119047619047619 1680 17224 9495,493 AKAP5,ATP2B4 GO:0032027 myosin light chain binding 0.109424292374946 -2.21252236268463 6 2 0.00119047619047619 1680 17224 128239,54558 IQGAP3,SPATA6 GO:0030345 structural constituent of tooth enamel 0.109424292374946 -2.21252236268463 6 2 0.00119047619047619 1680 17224 7286,10117 TUFT1,ENAM GO:0015189 L-lysine transmembrane transporter activity 0.109424292374946 -2.21252236268463 6 2 0.00119047619047619 1680 17224 6541,6542 SLC7A1,SLC7A2 GO:0008889 glycerophosphodiester phosphodiesterase activity 0.109424292374946 -2.21252236268463 6 2 0.00119047619047619 1680 17224 81544,133121 GDPD5,ENPP6 GO:0005375 copper ion transmembrane transporter activity 0.109424292374946 -2.21252236268463 6 2 0.00119047619047619 1680 17224 540,475 ATP7B,ATOX1 GO:0070097 delta-catenin binding 0.109424292374946 -2.21252236268463 6 2 0.00119047619047619 1680 17224 5795,51339 PTPRJ,DACT1 GO:0019534 toxin transmembrane transporter activity 0.109424292374946 -2.21252236268463 6 2 0.00119047619047619 1680 17224 4040,9619 LRP6,ABCG1 GO:0030021 extracellular matrix structural constituent conferring compression resistance 0.109424292374946 -2.21252236268463 6 2 0.00119047619047619 1680 17224 7286,10117 TUFT1,ENAM GO:0004720 protein-lysine 6-oxidase activity 0.109424292374946 -2.21252236268463 6 2 0.00119047619047619 1680 17224 84171,389643 LOXL4,NUGGC GO:0015181 arginine transmembrane transporter activity 0.109424292374946 -2.21252236268463 6 2 0.00119047619047619 1680 17224 6541,6542 SLC7A1,SLC7A2 GO:0015193 L-proline transmembrane transporter activity 0.109424292374946 -2.21252236268463 6 2 0.00119047619047619 1680 17224 120103,206358 SLC36A4,SLC36A1 GO:0030020 extracellular matrix structural constituent conferring tensile strength 0.109424292374946 -2.21252236268463 6 2 0.00119047619047619 1680 17224 1299,1298 COL9A3,COL9A2 GO:0019871 sodium channel inhibitor activity 0.109424292374946 -2.21252236268463 6 2 0.00119047619047619 1680 17224 6324,4734 SCN1B,NEDD4 GO:0050656 3'-phosphoadenosine 5'-phosphosulfate binding 0.109424292374946 -2.21252236268463 6 2 0.00119047619047619 1680 17224 5167,222537 ENPP1,HS3ST5 GO:0045159 myosin II binding 0.109424292374946 -2.21252236268463 6 2 0.00119047619047619 1680 17224 2934,257144 GSN,GCSAM GO:0001191 transcriptional repressor activity, RNA polymerase II transcription factor binding 0.109539758982105 -2.2114676999019 50 8 0.00476190476190476 1680 17224 57491,3399,3397,256536,8320,26508,83666,473 AHRR,ID3,ID1,TCERG1L,EOMES,HEYL,PARP9,RERE GO:0005245 voltage-gated calcium channel activity 0.109854440608465 -2.20859905667666 42 7 0.00416666666666667 1680 17224 2621,10368,785,783,777,23413,781 GAS6,CACNG3,CACNB4,CACNB2,CACNA1E,NCS1,CACNA2D1 GO:0070851 growth factor receptor binding 0.111426836391788 -2.19438707931797 127 17 0.0101190476190476 1680 17224 7424,10188,2241,685,10451,7039,3092,2625,8822,10464,2202,5795,23767,2081,3690,153090,5159 VEGFC,TNK2,FER,BTC,VAV3,TGFA,HIP1,GATA3,FGF17,PIBF1,EFEMP1,PTPRJ,FLRT3,ERN1,ITGB3,DAB2IP,PDGFRB GO:0003774 motor activity 0.112366784114976 -2.18598690018702 136 18 0.0107142857142857 1680 17224 57530,4642,4651,3798,4430,3800,23046,1780,1768,51626,140469,22989,55605,79659,144132,4646,1767,23095 CGN,MYO1D,MYO10,KIF5A,MYO1B,KIF5C,KIF21B,DYNC1I1,DNAH6,DYNC2LI1,MYO3B,MYH15,KIF21A,DYNC2H1,DNHD1,MYO6,DNAH5,KIF1B GO:0016645 oxidoreductase activity, acting on the CH-NH group of donors 0.116798778266053 -2.14730266869363 27 5 0.00297619047619048 1680 17224 10157,160428,645,10840,5831 AASS,ALDH1L2,BLVRB,ALDH1L1,PYCR1 GO:0003785 actin monomer binding 0.116798778266053 -2.14730266869363 27 5 0.00297619047619048 1680 17224 22837,11013,5217,23242,4846 COBLL1,TMSB15A,PFN2,COBL,NOS3 GO:0005198 structural molecule activity 0.118189197285662 -2.1354685717091 720 80 0.0476190476190476 1680 17224 51175,80781,5318,119,63827,54830,7373,1496,10382,23136,9053,1310,51121,80014,83660,4703,6207,7846,1285,26249,287,22941,56704,120892,7431,60485,1832,444,260425,4133,3912,142679,7168,5413,9863,84978,6224,1299,11149,152189,10319,29093,10174,1287,23521,85301,6164,51187,4130,6205,6525,23426,55964,1298,6228,57669,6154,10117,1286,6144,9455,3092,84033,23286,5357,10399,6641,4131,6136,6158,2200,143098,374383,9069,84034,7286,9172,6206,6124,4867 TUBE1,COL18A1,PKP2,ADD2,BCAN,NUP62CL,COL14A1,CTNNA2,TUBB4A,EPB41L3,MAP7,COL19A1,RPL26L1,WWC2,TLN2,NEB,RPS13,TUBA1A,COL4A3,KLHL3,ANK2,SHANK2,JPH1,LRRK2,VIM,SAV1,DSP,ASPH,MAGI3,MAP2,LAMB1,DUSP19,TPM1,SEPT5,MAGI2,FRMD5,RPS20,COL9A3,BVES,CMTM8,LAMC3,MRPL22,SORBS3,COL4A5,RPL13A,COL27A1,RPL34,RSL24D1,MAP1A,RPS11,SMTN,GRIP1,SEPT3,COL9A2,RPS23,EPB41L5,RPL26,ENAM,COL4A4,RPL21,HOMER2,HIP1,OBSCN,WWC1,PLS1,RACK1,SNTB1,MAP1B,RPL12,RPL28,FBN1,MPP7,NCR3LG1,CLDN12,EMILIN2,TUFT1,MYOM2,RPS12,RPL4,NPHP1 GO:0005319 lipid transporter activity 0.118207032369755 -2.13531768026592 137 18 0.0107142857142857 1680 17224 57088,84725,11001,10079,10396,10577,23250,57205,83985,23461,84879,153768,114879,134429,27166,5360,114880,9619 PLSCR4,PLEKHA8,SLC27A2,ATP9A,ATP8A1,NPC2,ATP11A,ATP10D,SPNS1,ABCA5,MFSD2A,PRELID2,OSBPL5,STARD4,PRELID1,PLTP,OSBPL6,ABCG1 GO:0001618 virus receptor activity 0.118701163768334 -2.13114617313207 76 11 0.00654761904761905 1680 17224 1948,2838,7301,3695,1604,3949,3673,3690,1380,6510,4684 EFNB2,GPR15,TYRO3,ITGB7,CD55,LDLR,ITGA2,ITGB3,CR2,SLC1A5,NCAM1 GO:0104005 hijacked molecular function 0.118701163768334 -2.13114617313207 76 11 0.00654761904761905 1680 17224 1948,2838,7301,3695,1604,3949,3673,3690,1380,6510,4684 EFNB2,GPR15,TYRO3,ITGB7,CD55,LDLR,ITGA2,ITGB3,CR2,SLC1A5,NCAM1 GO:0016860 intramolecular oxidoreductase activity 0.119448426982596 -2.12487057413256 51 8 0.00476190476190476 1680 17224 5768,3422,1962,84650,56605,9536,3690,81567 QSOX1,IDI1,EHHADH,EBPL,ERO1B,PTGES,ITGB3,TXNDC5 GO:0004715 non-membrane spanning protein tyrosine kinase activity 0.119448426982596 -2.12487057413256 51 8 0.00476190476190476 1680 17224 2241,10188,2268,5580,2444,79834,6850,2242 FER,TNK2,FGR,PRKCD,FRK,PEAK1,SYK,FES GO:0004497 monooxygenase activity 0.119820948934231 -2.12175674269296 102 14 0.00833333333333333 1680 17224 1595,9645,6307,8564,2329,1573,285440,5066,6713,113612,26002,1592,1545,4846 CYP51A1,MICAL2,MSMO1,KMO,FMO4,CYP2J2,CYP4V2,PAM,SQLE,CYP2U1,MOXD1,CYP26A1,CYP1B1,NOS3 GO:0008378 galactosyltransferase activity 0.120378574949913 -2.11711371086319 35 6 0.00357142857142857 1680 17224 23127,7368,8708,11285,9331,8707 COLGALT2,UGT8,B3GALT1,B4GALT7,B4GALT6,B3GALT2 GO:0005217 intracellular ligand-gated ion channel activity 0.120378574949913 -2.11711371086319 35 6 0.00357142857142857 1680 17224 6262,22821,255231,3709,56704,55283 RYR2,RASA3,MCOLN2,ITPR2,JPH1,MCOLN3 GO:0043394 proteoglycan binding 0.120378574949913 -2.11711371086319 35 6 0.00357142857142857 1680 17224 5802,3075,10855,9353,10082,3673 PTPRS,CFH,HPSE,SLIT2,GPC6,ITGA2 GO:0048029 monosaccharide binding 0.122725722203227 -2.09780331432748 68 10 0.00595238095238095 1680 17224 5352,8974,226,3099,5066,5033,10960,3098,10584,1203 PLOD2,P4HA2,ALDOA,HK2,PAM,P4HA1,LMAN2,HK1,COLEC10,CLN5 GO:0030215 semaphorin receptor binding 0.124131542223474 -2.08641345127081 20 4 0.00238095238095238 1680 17224 10512,10501,10505,10371 SEMA3C,SEMA6B,SEMA4F,SEMA3A GO:0070696 transmembrane receptor protein serine/threonine kinase binding 0.124131542223474 -2.08641345127081 20 4 0.00238095238095238 1680 17224 652,9863,4091,654 BMP4,MAGI2,SMAD6,BMP6 GO:0030742 GTP-dependent protein binding 0.124131542223474 -2.08641345127081 20 4 0.00238095238095238 1680 17224 5865,23682,10497,9771 RAB3B,RAB38,UNC13B,RAPGEF5 GO:0005086 ARF guanyl-nucleotide exchange factor activity 0.124131542223474 -2.08641345127081 20 4 0.00238095238095238 1680 17224 23362,23096,9265,57221 PSD3,IQSEC2,CYTH3,ARFGEF3 GO:0031418 L-ascorbic acid binding 0.124131542223474 -2.08641345127081 20 4 0.00238095238095238 1680 17224 5033,5352,8974,5066 P4HA1,PLOD2,P4HA2,PAM GO:0004012 phospholipid-translocating ATPase activity 0.124131542223474 -2.08641345127081 20 4 0.00238095238095238 1680 17224 23250,10079,57205,10396 ATP11A,ATP9A,ATP10D,ATP8A1 GO:0015077 monovalent inorganic cation transmembrane transporter activity 0.125917435780256 -2.07212885840018 388 45 0.0267857142857143 1680 17224 27012,6331,6536,2898,6334,90423,114134,9990,6507,3749,84679,219527,3761,7881,3781,6324,5002,27094,3790,154091,55117,6326,85414,92270,9312,6328,54795,56901,30818,6520,3786,285335,206358,27133,3752,481,55002,2900,60598,27345,3755,41,11182,150159,478 KCNV1,SCN5A,SLC6A9,GRIK2,SCN8A,ATP6V1E2,SLC2A13,SLC12A6,SLC1A3,KCNC4,SLC9A7,LRRC55,KCNJ4,KCNAB1,KCNN2,SCN1B,SLC22A18,KCNMB3,KCNS3,SLC2A12,SLC6A15,SCN2A,SLC45A3,ATP6AP1L,KCNB2,SCN3A,TRPM4,NDUFA4L2,KCNIP3,SLC3A2,KCNQ3,SLC9C1,SLC36A1,KCNH5,KCND3,ATP1B1,TMCO3,GRIK4,KCNK15,KCNMB4,KCNG1,ASIC1,SLC2A6,SLC9B1,ATP1A3 GO:0051287 NAD binding 0.126505110862998 -2.06747256955167 60 9 0.00535714285714286 1680 17224 217,2597,7358,56898,3248,1488,26227,83666,51084 ALDH2,GAPDH,UGDH,BDH2,HPGD,CTBP2,PHGDH,PARP9,CRYL1 GO:0016597 amino acid binding 0.126505110862998 -2.06747256955167 60 9 0.00535714285714286 1680 17224 23576,83667,6999,445,6507,27244,16,2731,4846 DDAH1,SESN2,TDO2,ASS1,SLC1A3,SESN1,AARS,GLDC,NOS3 GO:0070679 inositol 1,4,5 trisphosphate binding 0.12652931629596 -2.06728124828912 13 3 0.00178571428571429 1680 17224 7220,3709,7222 TRPC1,ITPR2,TRPC3 GO:0015385 sodium:proton antiporter activity 0.12652931629596 -2.06728124828912 13 3 0.00178571428571429 1680 17224 285335,150159,84679 SLC9C1,SLC9B1,SLC9A7 GO:0070402 NADPH binding 0.12652931629596 -2.06728124828912 13 3 0.00178571428571429 1680 17224 7881,2194,3156 KCNAB1,FASN,HMGCR GO:0008239 dipeptidyl-peptidase activity 0.12652931629596 -2.06728124828912 13 3 0.00178571428571429 1680 17224 57628,10279,5547 DPP10,PRSS16,PRCP GO:0016840 carbon-nitrogen lyase activity 0.12652931629596 -2.06728124828912 13 3 0.00178571428571429 1680 17224 79094,87769,5066 CHAC1,GGACT,PAM GO:0034595 phosphatidylinositol phosphate 5-phosphatase activity 0.12652931629596 -2.06728124828912 13 3 0.00178571428571429 1680 17224 22876,3636,9896 INPP5F,INPPL1,FIG4 GO:0044213 intronic transcription regulatory region DNA binding 0.12652931629596 -2.06728124828912 13 3 0.00178571428571429 1680 17224 64754,604,7080 SMYD3,BCL6,NKX2-1 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity 0.12652931629596 -2.06728124828912 13 3 0.00178571428571429 1680 17224 1852,1850,1843 DUSP9,DUSP8,DUSP1 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding 0.12652931629596 -2.06728124828912 13 3 0.00178571428571429 1680 17224 64754,604,7080 SMYD3,BCL6,NKX2-1 GO:0051219 phosphoprotein binding 0.126992781921384 -2.06362502940342 77 11 0.00654761904761905 1680 17224 11043,2268,6452,84959,5777,4281,6850,4734,2810,8945,6622 MID2,FGR,SH3BP2,UBASH3B,PTPN6,MID1,SYK,NEDD4,SFN,BTRC,SNCA GO:0043177 organic acid binding 0.127725204211028 -2.05787416493291 202 25 0.0148809523809524 1680 17224 83667,241,23670,6262,445,6507,63827,27244,9227,16,1592,6622,10247,23576,3399,3157,348751,5352,6999,8974,2172,5066,5033,2731,4846 SESN2,ALOX5AP,CEMIP2,RYR2,ASS1,SLC1A3,BCAN,SESN1,LRAT,AARS,CYP26A1,SNCA,RIDA,DDAH1,ID3,HMGCS1,FTCDNL1,PLOD2,TDO2,P4HA2,FABP6,PAM,P4HA1,GLDC,NOS3 GO:0022804 active transmembrane transporter activity 0.129168669720664 -2.04663621146226 370 43 0.0255952380952381 1680 17224 6536,10396,90423,120103,114134,9990,6507,28232,84679,90550,23657,51310,23461,6567,5002,84068,220963,55117,154091,353189,85414,92270,490,6520,54020,10257,285335,206358,1244,481,55002,540,84879,11182,8140,1015,81796,6510,150159,117247,493,9619,478 SLC6A9,ATP8A1,ATP6V1E2,SLC36A4,SLC2A13,SLC12A6,SLC1A3,SLCO3A1,SLC9A7,MCU,SLC7A11,SLC22A17,ABCA5,SLC16A2,SLC22A18,SLC10A7,SLC16A9,SLC6A15,SLC2A12,SLCO4C1,SLC45A3,ATP6AP1L,ATP2B1,SLC3A2,SLC37A1,ABCC4,SLC9C1,SLC36A1,ABCC2,ATP1B1,TMCO3,ATP7B,MFSD2A,SLC2A6,SLC7A5,CDH17,SLCO5A1,SLC1A5,SLC9B1,SLC16A10,ATP2B4,ABCG1,ATP1A3 GO:0051119 sugar transmembrane transporter activity 0.131416906862993 -2.02938051406247 28 5 0.00297619047619048 1680 17224 154091,148808,114134,85414,11182 SLC2A12,MFSD4A,SLC2A13,SLC45A3,SLC2A6 GO:0008200 ion channel inhibitor activity 0.13323614119027 -2.01563222742196 36 6 0.00357142857142857 1680 17224 27012,10399,6324,8673,4734,29763 KCNV1,RACK1,SCN1B,VAMP8,NEDD4,PACSIN3 GO:0032266 phosphatidylinositol-3-phosphate binding 0.13323614119027 -2.01563222742196 36 6 0.00357142857142857 1680 17224 3092,153090,25851,285590,57732,54477 HIP1,DAB2IP,TECPR1,SH3PXD2B,ZFYVE28,PLEKHA5 GO:0017022 myosin binding 0.136337634403941 -1.99262086390991 61 9 0.00535714285714286 1680 17224 2934,5865,257144,51560,54558,128239,5874,25924,270 GSN,RAB3B,GCSAM,RAB6B,SPATA6,IQGAP3,RAB27B,MYRIP,AMPD1 GO:0003714 transcription corepressor activity 0.139663894082636 -1.96851649936212 232 28 0.0166666666666667 1680 17224 29842,30818,4601,4212,10765,23051,23543,29995,6756,10413,1488,467,23414,256536,6497,473,55509,57761,9242,64324,3399,11278,26508,25937,51460,8531,284252,1649 TFCP2L1,KCNIP3,MXI1,MEIS2,KDM5B,ZHX3,RBFOX2,LMCD1,SSX1,YAP1,CTBP2,ATF3,ZFPM2,TCERG1L,SKI,RERE,BATF3,TRIB3,MSC,NSD1,ID3,KLF12,HEYL,WWTR1,SFMBT1,YBX3,KCTD1,DDIT3 GO:0005416 amino acid:cation symporter activity 0.142155032136839 -1.95083704132289 21 4 0.00238095238095238 1680 17224 55117,6536,6507,206358 SLC6A15,SLC6A9,SLC1A3,SLC36A1 GO:0003756 protein disulfide isomerase activity 0.142155032136839 -1.95083704132289 21 4 0.00238095238095238 1680 17224 5768,56605,3690,81567 QSOX1,ERO1B,ITGB3,TXNDC5 GO:0005355 glucose transmembrane transporter activity 0.142155032136839 -1.95083704132289 21 4 0.00238095238095238 1680 17224 154091,148808,114134,11182 SLC2A12,MFSD4A,SLC2A13,SLC2A6 GO:0033612 receptor serine/threonine kinase binding 0.142155032136839 -1.95083704132289 21 4 0.00238095238095238 1680 17224 652,9863,4091,654 BMP4,MAGI2,SMAD6,BMP6 GO:0000146 microfilament motor activity 0.142155032136839 -1.95083704132289 21 4 0.00238095238095238 1680 17224 4642,4646,4651,4430 MYO1D,MYO6,MYO10,MYO1B GO:0016864 intramolecular oxidoreductase activity, transposing S-S bonds 0.142155032136839 -1.95083704132289 21 4 0.00238095238095238 1680 17224 5768,56605,3690,81567 QSOX1,ERO1B,ITGB3,TXNDC5 GO:0017049 GTP-Rho binding 0.142155032136839 -1.95083704132289 21 4 0.00238095238095238 1680 17224 219790,5585,29941,29091 RTKN2,PKN1,PKN3,STXBP6 GO:0004703 G-protein coupled receptor kinase activity 0.143593680004248 -1.94076763444901 7 2 0.00119047619047619 1680 17224 2870,157 GRK6,GRK3 GO:0019798 procollagen-proline dioxygenase activity 0.143593680004248 -1.94076763444901 7 2 0.00119047619047619 1680 17224 5033,8974 P4HA1,P4HA2 GO:0072345 NAADP-sensitive calcium-release channel activity 0.143593680004248 -1.94076763444901 7 2 0.00119047619047619 1680 17224 255231,55283 MCOLN2,MCOLN3 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity 0.143593680004248 -1.94076763444901 7 2 0.00119047619047619 1680 17224 9953,222537 HS3ST3B1,HS3ST5 GO:0050291 sphingosine N-acyltransferase activity 0.143593680004248 -1.94076763444901 7 2 0.00119047619047619 1680 17224 79603,10715 CERS4,CERS1 GO:0004908 interleukin-1 receptor activity 0.143593680004248 -1.94076763444901 7 2 0.00119047619047619 1680 17224 8809,3556 IL18R1,IL1RAP GO:0008443 phosphofructokinase activity 0.143593680004248 -1.94076763444901 7 2 0.00119047619047619 1680 17224 5210,5208 PFKFB4,PFKFB2 GO:0004630 phospholipase D activity 0.143593680004248 -1.94076763444901 7 2 0.00119047619047619 1680 17224 5337,2822 PLD1,GPLD1 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides 0.143593680004248 -1.94076763444901 7 2 0.00119047619047619 1680 17224 26873,144193 OPLAH,AMDHD1 GO:0043184 vascular endothelial growth factor receptor 2 binding 0.143593680004248 -1.94076763444901 7 2 0.00119047619047619 1680 17224 153090,3690 DAB2IP,ITGB3 GO:0008046 axon guidance receptor activity 0.143593680004248 -1.94076763444901 7 2 0.00119047619047619 1680 17224 2047,6092 EPHB1,ROBO2 GO:0070728 leucine binding 0.143593680004248 -1.94076763444901 7 2 0.00119047619047619 1680 17224 83667,27244 SESN2,SESN1 GO:0022858 alanine transmembrane transporter activity 0.143593680004248 -1.94076763444901 7 2 0.00119047619047619 1680 17224 120103,206358 SLC36A4,SLC36A1 GO:0005004 GPI-linked ephrin receptor activity 0.143593680004248 -1.94076763444901 7 2 0.00119047619047619 1680 17224 2042,4916 EPHA3,NTRK3 GO:0003696 satellite DNA binding 0.143593680004248 -1.94076763444901 7 2 0.00119047619047619 1680 17224 26508,23462 HEYL,HEY1 GO:0008603 cAMP-dependent protein kinase regulator activity 0.143593680004248 -1.94076763444901 7 2 0.00119047619047619 1680 17224 3627,5577 CXCL10,PRKAR2B GO:0015180 L-alanine transmembrane transporter activity 0.143593680004248 -1.94076763444901 7 2 0.00119047619047619 1680 17224 120103,206358 SLC36A4,SLC36A1 GO:0004767 sphingomyelin phosphodiesterase activity 0.143593680004248 -1.94076763444901 7 2 0.00119047619047619 1680 17224 27293,10924 SMPDL3B,SMPDL3A GO:0008307 structural constituent of muscle 0.144279723075012 -1.93600134230675 45 7 0.00416666666666667 1680 17224 84033,9172,7168,444,4703,56704,6525 OBSCN,MYOM2,TPM1,ASPH,NEB,JPH1,SMTN GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding 0.146713289858093 -1.91927500585671 37 6 0.00357142857142857 1680 17224 10979,116984,4651,9265,4430,9846 FERMT2,ARAP2,MYO10,CYTH3,MYO1B,GAB2 GO:0016248 channel inhibitor activity 0.146713289858093 -1.91927500585671 37 6 0.00357142857142857 1680 17224 27012,10399,6324,8673,4734,29763 KCNV1,RACK1,SCN1B,VAMP8,NEDD4,PACSIN3 GO:0005251 delayed rectifier potassium channel activity 0.146810174854655 -1.91861485420461 29 5 0.00297619047619048 1680 17224 3786,3749,3755,9312,3790 KCNQ3,KCNC4,KCNG1,KCNB2,KCNS3 GO:0005344 oxygen carrier activity 0.149934877300741 -1.89755423048525 14 3 0.00178571428571429 1680 17224 3046,3048,26034 HBE1,HBG2,IPCEF1 GO:0005451 monovalent cation:proton antiporter activity 0.149934877300741 -1.89755423048525 14 3 0.00178571428571429 1680 17224 285335,150159,84679 SLC9C1,SLC9B1,SLC9A7 GO:0033549 MAP kinase phosphatase activity 0.149934877300741 -1.89755423048525 14 3 0.00178571428571429 1680 17224 1852,1850,1843 DUSP9,DUSP8,DUSP1 GO:0005528 FK506 binding 0.149934877300741 -1.89755423048525 14 3 0.00178571428571429 1680 17224 11328,55033,51303 FKBP9,FKBP14,FKBP11 GO:0004707 MAP kinase activity 0.149934877300741 -1.89755423048525 14 3 0.00178571428571429 1680 17224 5603,5596,5602 MAPK13,MAPK4,MAPK10 GO:0005527 macrolide binding 0.149934877300741 -1.89755423048525 14 3 0.00178571428571429 1680 17224 11328,55033,51303 FKBP9,FKBP14,FKBP11 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds 0.149934877300741 -1.89755423048525 14 3 0.00178571428571429 1680 17224 3422,1962,84650 IDI1,EHHADH,EBPL GO:0034236 protein kinase A catalytic subunit binding 0.149934877300741 -1.89755423048525 14 3 0.00178571428571429 1680 17224 6262,5577,5569 RYR2,PRKAR2B,PKIA GO:0019905 syntaxin binding 0.155708702973442 -1.85976830592111 89 12 0.00714285714285714 1680 17224 8448,9515,10497,91683,120892,55638,54732,6616,255928,6812,123036,9751 DOC2A,STXBP5L,UNC13B,SYT12,LRRK2,SYBU,TMED9,SNAP25,SYT14,STXBP1,TC2N,SNPH GO:0003700 DNA binding transcription factor activity 0.155833275384031 -1.85896859078875 1759 184 0.10952380952381 1680 17224 2625,6777,1050,22807,117154,7227,6497,64376,8320,29841,1750,11262,2115,2023,114821,5455,346157,7080,30818,468,4212,4093,2649,4774,147929,4779,100271849,10538,388507,57491,83439,10781,3131,11278,26137,1746,63973,63920,4300,11178,4208,64919,11279,860,55893,23051,219749,122953,9569,26040,7762,7546,6304,2290,2122,158405,253461,6940,126070,2624,4609,85416,6720,57593,85460,148979,56033,25946,1052,23361,30062,6775,84159,100289635,7468,9935,639,6875,148156,5325,26508,3239,26257,10736,64764,29842,5071,3397,9658,282890,5013,55769,255877,221833,79149,149076,220929,5462,26468,604,25925,5452,10794,4661,57670,93349,6591,2735,11166,579,59336,23314,467,474,114991,55509,53335,148266,7552,252884,4088,9242,81931,22806,60468,90874,54937,688,657,1628,3219,4306,29942,55762,23462,4601,5966,5324,56978,9586,58495,51222,84525,4825,93986,10265,168620,2334,7020,8848,687,8531,2672,4091,678,4487,10765,3174,1112,2104,3164,9516,23414,3198,7545,283078,473,1879,1051,643836,3399,138151,91133,7761,7494,7703,388558,745,5083,56906,6474,3169,1649,9310 GATA3,STAT5B,CEBPA,IKZF2,DACH2,TRPS1,SKI,IKZF5,EOMES,GRHL1,DLX6,SP140,ETV1,ENO1,ZBED9,POU3F3,ZNF391,NKX2-1,KCNIP3,ATF4,MEIS2,SMAD9,NR6A1,NFIA,ZNF565,NFE2L1,MEF2B,BATF,ZNF788P,AHRR,TCF7L1,ZNF266,HLF,KLF12,ZBTB20,DLX2,NEUROG2,ZBED8,MLLT3,LZTS1,MEF2C,BCL11B,KLF8,RUNX2,ZNF395,ZHX3,ZNF25,JDP2,GTF2IRD1,SETBP1,ZNF215,ZIC2,SATB1,FOXG1,MECOM,KIAA1958,ZBTB38,ZNF354A,ZNF440,GATA2,MYC,ZIC5,SREBF1,EBF4,ZNF518B,GLIS1,BARX1,ZNF385A,CEBPD,ZNF629,RAX,STAT4,ARID5B,ZNF605,NSD2,MAFB,PRDM1,TAF4B,ZNF558,PLAGL1,HEYL,HOXD13,NKX2-8,SIX2,CREB3L2,TFCP2L1,PRKN,ID1,ZNF516,ZNF311,OTX1,ZNF83,BCL6B,SP8,ZSCAN5A,ZNF362,ZNF438,POU5F1B,LHX6,BCL6,ZNF521,POU2F2,ZNF460,MYT1,KIAA1549,SP140L,SNAI2,GLI1,SOX21,NKX3-2,PRDM13,SATB2,ATF3,ATOH1,ZNF618,BATF3,BCL11A,ZNF569,ZNF711,ZNF396,SMAD3,MSC,ZNF93,IKZF3,BACH2,ZNF697,SOHLH2,KLF5,BMPR1A,DBP,HOXB9,NR3C2,PURG,ZNF701,HEY1,MXI1,REL,PLAG1,PRDM8,CREB5,OVOL2,ZNF219,HOPX,NKX6-1,FOXP2,IRX5,BHLHA15,AFF2,TFAP2A,TSC22D1,KLF9,YBX3,GFI1,SMAD6,ZFP36L2,MSX1,KDM5B,HNF4G,FOXN3,ESRRG,NR4A1,LITAF,ZFPM2,HOXA1,ZIC1,MKX,RERE,EBF1,CEBPB,ZFP62,ID3,NACC2,L3MBTL4,ZNF214,XBP1,PCGF2,ZNF808,MYRF,PAX9,THAP10,SHOX2,FOXA1,DDIT3,ZNF235 GO:0008138 protein tyrosine/serine/threonine phosphatase activity 0.156776761316716 -1.8529323879377 46 7 0.00416666666666667 1680 17224 1852,54961,1850,8555,27143,142679,1843 DUSP9,SSH3,DUSP8,CDC14B,PALD1,DUSP19,DUSP1 GO:0044325 ion channel binding 0.157710310497911 -1.84699540669435 107 14 0.00833333333333333 1680 17224 57628,219527,6331,2258,285966,287,120892,2257,5318,6262,3752,5144,9699,9709 DPP10,LRRC55,SCN5A,FGF13,TCAF2,ANK2,LRRK2,FGF12,PKP2,RYR2,KCND3,PDE4D,RIMS2,HERPUD1 GO:0017137 Rab GTPase binding 0.159216939013902 -1.83748761039093 180 22 0.0130952380952381 1680 17224 23086,23312,54453,9515,54885,23216,9853,22898,125058,23329,55357,113622,26056,10497,23158,79958,9882,25924,9699,160518,11138,57531 EXPH5,DMXL2,RIN2,STXBP5L,TBC1D8B,TBC1D1,RUSC2,DENND3,TBC1D16,TBC1D30,TBC1D2,ADPRHL1,RAB11FIP5,UNC13B,TBC1D9,DENND1C,TBC1D4,MYRIP,RIMS2,DENND5B,TBC1D8,HACE1 GO:1904315 transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential 0.160778475894208 -1.82772778757614 38 6 0.00357142857142857 1680 17224 2566,8973,2900,1138,2898,2894 GABRG2,CHRNA6,GRIK4,CHRNA5,GRIK2,GRID1 GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential 0.160778475894208 -1.82772778757614 38 6 0.00357142857142857 1680 17224 2566,8973,2900,1138,2898,2894 GABRG2,CHRNA6,GRIK4,CHRNA5,GRIK2,GRID1 GO:0015149 hexose transmembrane transporter activity 0.161133844901738 -1.82551992457164 22 4 0.00238095238095238 1680 17224 154091,148808,114134,11182 SLC2A12,MFSD4A,SLC2A13,SLC2A6 GO:0019200 carbohydrate kinase activity 0.161133844901738 -1.82551992457164 22 4 0.00238095238095238 1680 17224 5210,3098,5208,3099 PFKFB4,HK1,PFKFB2,HK2 GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors 0.161133844901738 -1.82551992457164 22 4 0.00238095238095238 1680 17224 4128,84171,389643,2731 MAOA,LOXL4,NUGGC,GLDC GO:0043014 alpha-tubulin binding 0.162926957767603 -1.81445329046269 30 5 0.00297619047619048 1680 17224 56271,114327,10891,79739,6622 BEX4,EFHC1,PPARGC1A,TTLL7,SNCA GO:0016417 S-acyltransferase activity 0.162926957767603 -1.81445329046269 30 5 0.00297619047619048 1680 17224 79683,64429,158866,254887,2194 ZDHHC14,ZDHHC6,ZDHHC15,ZDHHC23,FASN GO:0004177 aminopeptidase activity 0.169748676833067 -1.77343630737155 47 7 0.00416666666666667 1680 17224 57628,4324,10279,4325,5547,1515,254042 DPP10,MMP15,PRSS16,MMP16,PRCP,CTSV,METAP1D GO:0050661 NADP binding 0.169748676833067 -1.77343630737155 47 7 0.00416666666666667 1680 17224 2597,7881,1717,2329,4846,2194,3156 GAPDH,KCNAB1,DHCR7,FMO4,NOS3,FASN,HMGCR GO:0019825 oxygen binding 0.169748676833067 -1.77343630737155 47 7 0.00416666666666667 1680 17224 875,3048,3046,113612,6999,1592,1545 CBS,HBG2,HBE1,CYP2U1,TDO2,CYP26A1,CYP1B1 GO:0030276 clathrin binding 0.171088405645226 -1.76557486399649 73 10 0.00595238095238095 1680 17224 8448,91683,122616,3949,120892,9829,3092,255928,92737,123036 DOC2A,SYT12,CLBA1,LDLR,LRRK2,DNAJC6,HIP1,SYT14,DNER,TC2N GO:0019903 protein phosphatase binding 0.174440161291719 -1.74617351138223 109 14 0.00833333333333333 1680 17224 116154,2241,9495,10859,153090,10399,55917,25827,4233,8631,1000,55607,493,91272 PHACTR3,FER,AKAP5,LILRB1,DAB2IP,RACK1,CTTNBP2NL,FBXL2,MET,SKAP1,CDH2,PPP1R9A,ATP2B4,BOD1 GO:0034483 heparan sulfate sulfotransferase activity 0.174580529573117 -1.74536915626725 15 3 0.00178571428571429 1680 17224 9953,222537,266722 HS3ST3B1,HS3ST5,HS6ST3 GO:0004089 carbonate dehydratase activity 0.174580529573117 -1.74536915626725 15 3 0.00178571428571429 1680 17224 760,767,377677 CA2,CA8,CA13 GO:0008191 metalloendopeptidase inhibitor activity 0.174580529573117 -1.74536915626725 15 3 0.00178571428571429 1680 17224 1285,8434,50859 COL4A3,RECK,SPOCK3 GO:0004029 aldehyde dehydrogenase (NAD) activity 0.174580529573117 -1.74536915626725 15 3 0.00178571428571429 1680 17224 217,160428,10840 ALDH2,ALDH1L2,ALDH1L1 GO:0004708 MAP kinase kinase activity 0.174580529573117 -1.74536915626725 15 3 0.00178571428571429 1680 17224 5602,5608,120892 MAPK10,MAP2K6,LRRK2 GO:0004871 signal transducer activity 0.176952060225481 -1.73187642927748 1819 189 0.1125 1680 17224 90,55366,2898,55283,10859,6777,3709,92737,5881,8428,2152,8153,7049,3690,54732,2051,343171,5791,7099,7253,3556,5159,3695,4093,130399,1630,2649,79971,56704,120892,1380,93,4919,26512,10082,58473,25987,285601,2770,51704,10769,59345,153,7132,5603,5021,166647,8829,219699,9863,23266,7301,81491,55970,9902,9620,9886,5789,2561,8794,924,55504,8809,55816,57211,2202,255231,3480,23767,6720,23596,4040,23554,2674,23432,1131,8643,2264,11245,8633,627,54756,23433,6775,7436,1944,6262,10203,387914,390442,23236,2842,9261,2900,577,5799,643,2042,6785,29984,1951,8477,5362,5596,4916,3597,79339,1147,9378,780,26230,2838,7098,1138,51310,22859,92,51454,4233,9846,8321,118429,8322,10076,27133,5777,8973,958,2260,8660,3363,4088,10718,26996,5754,3673,84451,3248,657,5602,4306,3977,282763,23043,9170,6092,60401,659,8325,4038,2566,5028,2570,2047,54602,6000,51222,576,4756,2690,4091,8792,6850,27077,51232,3174,9693,2104,3164,9516,2894,22821,10399,10333,3953,22943,2861,5788,391195,390,2775,5608,4163,2906,79705,608,6510,3581,51776 ACVR1,LGR4,GRIK2,MCOLN3,LILRB1,STAT5B,ITPR2,DNER,RAC3,STK24,F3,RND2,TGFBR3,ITGB3,TMED9,EPHB6,OR2W3,PTPRE,TLR4,TSHR,IL1RAP,PDGFRB,ITGB7,SMAD9,ACVR1C,DCC,NR6A1,WLS,JPH1,LRRK2,CR2,ACVR2B,ROR1,INTS6,GPC6,PLEKHB1,TSKU,GPR150,GNAI1,GPRC5B,PLK2,GNB4,ADRB1,TNFRSF1A,MAPK13,OXTR,ADGRA3,NRP1,UNC5B,MAGI2,ADGRL2,TYRO3,GPR63,GNG12,MRC2,CELSR1,RHOBTB1,PTPRD,GABRB2,TNFRSF10C,CD7,TNFRSF19,IL18R1,DOK5,ADGRG6,EFEMP1,MCOLN2,IGF1R,FLRT3,SREBF1,OPN3,LRP6,TSPAN12,GFRA1,GPR161,CHRM3,PTCH2,FGFR4,GPR176,UNC5C,BDNF,IL17RD,RHOQ,STAT4,VLDLR,EFNA3,RYR2,CALCRL,SHISA2,OR11H4,PLCB1,GPR19,MAPKAPK2,GRIK4,ADGRB3,PTPRN2,CXCR5,EPHA3,ELOVL4,RHOD,CELSR3,GPR65,PLXNA2,MAPK4,NTRK3,IL13RA1,OR51B4,CHUK,NRXN1,DDR1,TIAM2,GPR15,TLR3,CHRNA5,SLC22A17,ADGRL1,ACVR2A,GULP1,MET,GAB2,FZD1,ANTXR2,FZD4,PTPRU,KCNH5,PTPN6,CHRNA6,CD40,FGFR1,IRS2,HTR7,SMAD3,NRG3,GPR160,PTK7,ITGA2,MAP3K21,HPGD,BMPR1A,MAPK10,NR3C2,LIFR,OR51B5,TNIK,LPAR2,ROBO2,EDA2R,BMPR2,FZD8,LRP4,GABRG2,P2RY1,GABRR2,EPHB1,NDFIP2,RGS7,ZNF219,ADGRB2,NEO1,GHR,SMAD6,TNFRSF11A,SYK,B9D1,CRIM1,HNF4G,RAPGEF2,ESRRG,NR4A1,LITAF,GRID1,RASA3,RACK1,TLR6,LEPR,DKK1,GPR37,PTPRC,OR2T33,RND3,GNAO1,MAP2K6,MCC,GRIN2D,LRRK1,TNFRSF17,SLC1A5,IL9R,MAP3K20 GO:0004771 sterol esterase activity 0.179572720121926 -1.71717502706775 8 2 0.00119047619047619 1680 17224 57552,23491 NCEH1,CES3 GO:0031995 insulin-like growth factor II binding 0.179572720121926 -1.71717502706775 8 2 0.00119047619047619 1680 17224 3489,3486 IGFBP6,IGFBP3 GO:0016742 hydroxymethyl-, formyl- and related transferase activity 0.179572720121926 -1.71717502706775 8 2 0.00119047619047619 1680 17224 160428,10840 ALDH1L2,ALDH1L1 GO:0031956 medium-chain fatty acid-CoA ligase activity 0.179572720121926 -1.71717502706775 8 2 0.00119047619047619 1680 17224 2180,11001 ACSL1,SLC27A2 GO:0015187 glycine transmembrane transporter activity 0.179572720121926 -1.71717502706775 8 2 0.00119047619047619 1680 17224 6536,206358 SLC6A9,SLC36A1 GO:0016427 tRNA (cytosine) methyltransferase activity 0.179572720121926 -1.71717502706775 8 2 0.00119047619047619 1680 17224 1787,221078 TRDMT1,NSUN6 GO:0000064 L-ornithine transmembrane transporter activity 0.179572720121926 -1.71717502706775 8 2 0.00119047619047619 1680 17224 6541,6542 SLC7A1,SLC7A2 GO:0102391 decanoate-CoA ligase activity 0.179572720121926 -1.71717502706775 8 2 0.00119047619047619 1680 17224 2180,11001 ACSL1,SLC27A2 GO:0016615 malate dehydrogenase activity 0.179572720121926 -1.71717502706775 8 2 0.00119047619047619 1680 17224 130752,26227 MDH1B,PHGDH GO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity 0.179572720121926 -1.71717502706775 8 2 0.00119047619047619 1680 17224 11285,9331 B4GALT7,B4GALT6 GO:0070697 activin receptor binding 0.179572720121926 -1.71717502706775 8 2 0.00119047619047619 1680 17224 9863,4091 MAGI2,SMAD6 GO:0048027 mRNA 5'-UTR binding 0.180968230831456 -1.70943378338999 23 4 0.00238095238095238 1680 17224 6154,10644,23367,6207 RPL26,IGF2BP2,LARP1,RPS13 GO:0019902 phosphatase binding 0.18438947642593 -1.69070503876185 156 19 0.0113095238095238 1680 17224 116154,2241,9495,10859,55917,10399,8631,55607,4088,9858,153090,11123,4233,25827,1000,9863,6850,493,91272 PHACTR3,FER,AKAP5,LILRB1,CTTNBP2NL,RACK1,SKAP1,PPP1R9A,SMAD3,PPP1R26,DAB2IP,RCAN3,MET,FBXL2,CDH2,MAGI2,SYK,ATP2B4,BOD1 GO:0000991 transcription factor activity, core RNA polymerase II binding 0.185568024515725 -1.6843337551763 2 1 0.000595238095238095 1680 17224 2963 GTF2F2 GO:0102965 alcohol-forming fatty acyl-CoA reductase activity 0.185568024515725 -1.6843337551763 2 1 0.000595238095238095 1680 17224 55711 FAR2 GO:0004081 bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) activity 0.185568024515725 -1.6843337551763 2 1 0.000595238095238095 1680 17224 2617 GARS GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity 0.185568024515725 -1.6843337551763 2 1 0.000595238095238095 1680 17224 6480 ST6GAL1 GO:0030305 heparanase activity 0.185568024515725 -1.6843337551763 2 1 0.000595238095238095 1680 17224 10855 HPSE GO:0103073 anandamide amidohydrolase activity 0.185568024515725 -1.6843337551763 2 1 0.000595238095238095 1680 17224 158584 FAAH2 GO:0017161 inositol-1,3,4-trisphosphate 4-phosphatase activity 0.185568024515725 -1.6843337551763 2 1 0.000595238095238095 1680 17224 8821 INPP4B GO:0102077 oleamide hydrolase activity 0.185568024515725 -1.6843337551763 2 1 0.000595238095238095 1680 17224 158584 FAAH2 GO:0030109 HLA-B specific inhibitory MHC class I receptor activity 0.185568024515725 -1.6843337551763 2 1 0.000595238095238095 1680 17224 10859 LILRB1 GO:0003875 ADP-ribosylarginine hydrolase activity 0.185568024515725 -1.6843337551763 2 1 0.000595238095238095 1680 17224 113622 ADPRHL1 GO:0004830 tryptophan-tRNA ligase activity 0.185568024515725 -1.6843337551763 2 1 0.000595238095238095 1680 17224 7453 WARS GO:0034988 Fc-gamma receptor I complex binding 0.185568024515725 -1.6843337551763 2 1 0.000595238095238095 1680 17224 2268 FGR GO:0050405 [acetyl-CoA carboxylase] kinase activity 0.185568024515725 -1.6843337551763 2 1 0.000595238095238095 1680 17224 5563 PRKAA2 GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity 0.185568024515725 -1.6843337551763 2 1 0.000595238095238095 1680 17224 107 ADCY1 GO:0005292 high-affinity lysine transmembrane transporter activity 0.185568024515725 -1.6843337551763 2 1 0.000595238095238095 1680 17224 6542 SLC7A2 GO:0019002 GMP binding 0.185568024515725 -1.6843337551763 2 1 0.000595238095238095 1680 17224 25837 RAB26 GO:0017064 fatty acid amide hydrolase activity 0.185568024515725 -1.6843337551763 2 1 0.000595238095238095 1680 17224 158584 FAAH2 GO:0047635 alanine-oxo-acid transaminase activity 0.185568024515725 -1.6843337551763 2 1 0.000595238095238095 1680 17224 84706 GPT2 GO:0005427 proton-dependent oligopeptide secondary active transmembrane transporter activity 0.185568024515725 -1.6843337551763 2 1 0.000595238095238095 1680 17224 1015 CDH17 GO:0002114 interleukin-33 receptor activity 0.185568024515725 -1.6843337551763 2 1 0.000595238095238095 1680 17224 3556 IL1RAP GO:0016403 dimethylargininase activity 0.185568024515725 -1.6843337551763 2 1 0.000595238095238095 1680 17224 23576 DDAH1 GO:0140031 phosphorylation-dependent protein binding 0.185568024515725 -1.6843337551763 2 1 0.000595238095238095 1680 17224 5777 PTPN6 GO:0070699 type II activin receptor binding 0.185568024515725 -1.6843337551763 2 1 0.000595238095238095 1680 17224 9863 MAGI2 GO:0016316 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity 0.185568024515725 -1.6843337551763 2 1 0.000595238095238095 1680 17224 8821 INPP4B GO:0016419 S-malonyltransferase activity 0.185568024515725 -1.6843337551763 2 1 0.000595238095238095 1680 17224 2194 FASN GO:0015322 secondary active oligopeptide transmembrane transporter activity 0.185568024515725 -1.6843337551763 2 1 0.000595238095238095 1680 17224 1015 CDH17 GO:0036461 BLOC-2 complex binding 0.185568024515725 -1.6843337551763 2 1 0.000595238095238095 1680 17224 23682 RAB38 GO:0003721 telomerase RNA reverse transcriptase activity 0.185568024515725 -1.6843337551763 2 1 0.000595238095238095 1680 17224 7015 TERT GO:0080023 3R-hydroxyacyl-CoA dehydratase activity 0.185568024515725 -1.6843337551763 2 1 0.000595238095238095 1680 17224 9200 HACD1 GO:0004008 copper-exporting ATPase activity 0.185568024515725 -1.6843337551763 2 1 0.000595238095238095 1680 17224 540 ATP7B GO:0046811 histone deacetylase inhibitor activity 0.185568024515725 -1.6843337551763 2 1 0.000595238095238095 1680 17224 6497 SKI GO:0005019 platelet-derived growth factor beta-receptor activity 0.185568024515725 -1.6843337551763 2 1 0.000595238095238095 1680 17224 5159 PDGFRB GO:0030350 iron-responsive element binding 0.185568024515725 -1.6843337551763 2 1 0.000595238095238095 1680 17224 48 ACO1 GO:0004421 hydroxymethylglutaryl-CoA synthase activity 0.185568024515725 -1.6843337551763 2 1 0.000595238095238095 1680 17224 3157 HMGCS1 GO:0004066 asparagine synthase (glutamine-hydrolyzing) activity 0.185568024515725 -1.6843337551763 2 1 0.000595238095238095 1680 17224 440 ASNS GO:0031704 apelin receptor binding 0.185568024515725 -1.6843337551763 2 1 0.000595238095238095 1680 17224 100506013 APELA GO:0043185 vascular endothelial growth factor receptor 3 binding 0.185568024515725 -1.6843337551763 2 1 0.000595238095238095 1680 17224 7424 VEGFC GO:0005298 proline:sodium symporter activity 0.185568024515725 -1.6843337551763 2 1 0.000595238095238095 1680 17224 55117 SLC6A15 GO:0086020 gap junction channel activity involved in SA node cell-atrial cardiac muscle cell electrical coupling 0.185568024515725 -1.6843337551763 2 1 0.000595238095238095 1680 17224 10052 GJC1 GO:0106073 dolichyl pyrophosphate Glc2Man9GlcNAc2 alpha-1,2-glucosyltransferase activity 0.185568024515725 -1.6843337551763 2 1 0.000595238095238095 1680 17224 144245 ALG10B GO:0070698 type I activin receptor binding 0.185568024515725 -1.6843337551763 2 1 0.000595238095238095 1680 17224 4091 SMAD6 GO:0047750 cholestenol delta-isomerase activity 0.185568024515725 -1.6843337551763 2 1 0.000595238095238095 1680 17224 84650 EBPL GO:0032810 sterol response element binding 0.185568024515725 -1.6843337551763 2 1 0.000595238095238095 1680 17224 6720 SREBF1 GO:0047710 bis(5'-adenosyl)-triphosphatase activity 0.185568024515725 -1.6843337551763 2 1 0.000595238095238095 1680 17224 2272 FHIT GO:0032427 GBD domain binding 0.185568024515725 -1.6843337551763 2 1 0.000595238095238095 1680 17224 23433 RHOQ GO:0035575 histone demethylase activity (H4-K20 specific) 0.185568024515725 -1.6843337551763 2 1 0.000595238095238095 1680 17224 80853 KDM7A GO:0004820 glycine-tRNA ligase activity 0.185568024515725 -1.6843337551763 2 1 0.000595238095238095 1680 17224 2617 GARS GO:0046556 alpha-L-arabinofuranosidase activity 0.185568024515725 -1.6843337551763 2 1 0.000595238095238095 1680 17224 283310 OTOGL GO:0004923 leukemia inhibitory factor receptor activity 0.185568024515725 -1.6843337551763 2 1 0.000595238095238095 1680 17224 3977 LIFR GO:0047389 glycerophosphocholine phosphodiesterase activity 0.185568024515725 -1.6843337551763 2 1 0.000595238095238095 1680 17224 81544 GDPD5 GO:0035402 histone kinase activity (H3-T11 specific) 0.185568024515725 -1.6843337551763 2 1 0.000595238095238095 1680 17224 5585 PKN1 GO:0005365 myo-inositol transmembrane transporter activity 0.185568024515725 -1.6843337551763 2 1 0.000595238095238095 1680 17224 114134 SLC2A13 GO:0080019 fatty-acyl-CoA reductase (alcohol-forming) activity 0.185568024515725 -1.6843337551763 2 1 0.000595238095238095 1680 17224 55711 FAR2 GO:0004458 D-lactate dehydrogenase (cytochrome) activity 0.185568024515725 -1.6843337551763 2 1 0.000595238095238095 1680 17224 197257 LDHD GO:1904713 beta-catenin destruction complex binding 0.185568024515725 -1.6843337551763 2 1 0.000595238095238095 1680 17224 120892 LRRK2 GO:0070853 myosin VI binding 0.185568024515725 -1.6843337551763 2 1 0.000595238095238095 1680 17224 128239 IQGAP3 GO:0046899 nucleoside triphosphate adenylate kinase activity 0.185568024515725 -1.6843337551763 2 1 0.000595238095238095 1680 17224 205 AK4 GO:0030617 transforming growth factor beta receptor, inhibitory cytoplasmic mediator activity 0.185568024515725 -1.6843337551763 2 1 0.000595238095238095 1680 17224 4091 SMAD6 GO:0004817 cysteine-tRNA ligase activity 0.185568024515725 -1.6843337551763 2 1 0.000595238095238095 1680 17224 833 CARS GO:0004422 hypoxanthine phosphoribosyltransferase activity 0.185568024515725 -1.6843337551763 2 1 0.000595238095238095 1680 17224 56952 PRTFDC1 GO:0047409 alkenylglycerophosphoethanolamine hydrolase activity 0.185568024515725 -1.6843337551763 2 1 0.000595238095238095 1680 17224 144110 TMEM86A GO:1990409 adrenomedullin binding 0.185568024515725 -1.6843337551763 2 1 0.000595238095238095 1680 17224 10203 CALCRL GO:0003990 acetylcholinesterase activity 0.185568024515725 -1.6843337551763 2 1 0.000595238095238095 1680 17224 590 BCHE GO:0045031 ATP-activated adenosine receptor activity 0.185568024515725 -1.6843337551763 2 1 0.000595238095238095 1680 17224 5028 P2RY1 GO:0016418 S-acetyltransferase activity 0.185568024515725 -1.6843337551763 2 1 0.000595238095238095 1680 17224 2194 FASN GO:0015292 uniporter activity 0.185568024515725 -1.6843337551763 2 1 0.000595238095238095 1680 17224 90550 MCU GO:0004772 sterol O-acyltransferase activity 0.185568024515725 -1.6843337551763 2 1 0.000595238095238095 1680 17224 8435 SOAT2 GO:0032542 sulfiredoxin activity 0.185568024515725 -1.6843337551763 2 1 0.000595238095238095 1680 17224 83667 SESN2 GO:0071633 dihydroceramidase activity 0.185568024515725 -1.6843337551763 2 1 0.000595238095238095 1680 17224 340485 ACER2 GO:0047408 alkenylglycerophosphocholine hydrolase activity 0.185568024515725 -1.6843337551763 2 1 0.000595238095238095 1680 17224 144110 TMEM86A GO:0050185 phosphatidylinositol deacylase activity 0.185568024515725 -1.6843337551763 2 1 0.000595238095238095 1680 17224 80055 PGAP1 GO:0008160 protein tyrosine phosphatase activator activity 0.185568024515725 -1.6843337551763 2 1 0.000595238095238095 1680 17224 3486 IGFBP3 GO:0004452 isopentenyl-diphosphate delta-isomerase activity 0.185568024515725 -1.6843337551763 2 1 0.000595238095238095 1680 17224 3422 IDI1 GO:0038025 reelin receptor activity 0.185568024515725 -1.6843337551763 2 1 0.000595238095238095 1680 17224 7436 VLDLR GO:0004798 thymidylate kinase activity 0.185568024515725 -1.6843337551763 2 1 0.000595238095238095 1680 17224 129607 CMPK2 GO:0004314 [acyl-carrier-protein] S-malonyltransferase activity 0.185568024515725 -1.6843337551763 2 1 0.000595238095238095 1680 17224 2194 FASN GO:0004613 phosphoenolpyruvate carboxykinase (GTP) activity 0.185568024515725 -1.6843337551763 2 1 0.000595238095238095 1680 17224 5106 PCK2 GO:0052828 inositol-3,4-bisphosphate 4-phosphatase activity 0.185568024515725 -1.6843337551763 2 1 0.000595238095238095 1680 17224 8821 INPP4B GO:0004996 thyroid-stimulating hormone receptor activity 0.185568024515725 -1.6843337551763 2 1 0.000595238095238095 1680 17224 7253 TSHR GO:0000248 C-5 sterol desaturase activity 0.185568024515725 -1.6843337551763 2 1 0.000595238095238095 1680 17224 3992 FADS1 GO:0008796 bis(5'-nucleosyl)-tetraphosphatase activity 0.185568024515725 -1.6843337551763 2 1 0.000595238095238095 1680 17224 2617 GARS GO:0034189 very-low-density lipoprotein particle binding 0.185568024515725 -1.6843337551763 2 1 0.000595238095238095 1680 17224 7436 VLDLR GO:0043891 glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity 0.185568024515725 -1.6843337551763 2 1 0.000595238095238095 1680 17224 2597 GAPDH GO:0004365 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity 0.185568024515725 -1.6843337551763 2 1 0.000595238095238095 1680 17224 2597 GAPDH GO:0004074 biliverdin reductase activity 0.185568024515725 -1.6843337551763 2 1 0.000595238095238095 1680 17224 645 BLVRB GO:1904928 coreceptor activity involved in canonical Wnt signaling pathway 0.185568024515725 -1.6843337551763 2 1 0.000595238095238095 1680 17224 4040 LRP6 GO:0004019 adenylosuccinate synthase activity 0.185568024515725 -1.6843337551763 2 1 0.000595238095238095 1680 17224 122622 ADSSL1 GO:0030272 5-formyltetrahydrofolate cyclo-ligase activity 0.185568024515725 -1.6843337551763 2 1 0.000595238095238095 1680 17224 93974 ATP5IF1 GO:0017089 glycolipid transporter activity 0.185568024515725 -1.6843337551763 2 1 0.000595238095238095 1680 17224 84725 PLEKHA8 GO:0061928 glutathione specific gamma-glutamylcyclotransferase activity 0.185568024515725 -1.6843337551763 2 1 0.000595238095238095 1680 17224 79094 CHAC1 GO:0004948 calcitonin receptor activity 0.185568024515725 -1.6843337551763 2 1 0.000595238095238095 1680 17224 10203 CALCRL GO:0005052 peroxisome matrix targeting signal-1 binding 0.185568024515725 -1.6843337551763 2 1 0.000595238095238095 1680 17224 51555 PEX5L GO:0038062 protein tyrosine kinase collagen receptor activity 0.185568024515725 -1.6843337551763 2 1 0.000595238095238095 1680 17224 780 DDR1 GO:0004021 L-alanine:2-oxoglutarate aminotransferase activity 0.185568024515725 -1.6843337551763 2 1 0.000595238095238095 1680 17224 84706 GPT2 GO:0034736 cholesterol O-acyltransferase activity 0.185568024515725 -1.6843337551763 2 1 0.000595238095238095 1680 17224 8435 SOAT2 GO:0005289 high-affinity arginine transmembrane transporter activity 0.185568024515725 -1.6843337551763 2 1 0.000595238095238095 1680 17224 6542 SLC7A2 GO:0032767 copper-dependent protein binding 0.185568024515725 -1.6843337551763 2 1 0.000595238095238095 1680 17224 475 ATOX1 GO:0098680 template-free RNA nucleotidyltransferase 0.185568024515725 -1.6843337551763 2 1 0.000595238095238095 1680 17224 7015 TERT GO:0008798 beta-aspartyl-peptidase activity 0.185568024515725 -1.6843337551763 2 1 0.000595238095238095 1680 17224 23621 BACE1 GO:0004731 purine-nucleoside phosphorylase activity 0.185568024515725 -1.6843337551763 2 1 0.000595238095238095 1680 17224 4860 PNP GO:0033842 N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase activity 0.185568024515725 -1.6843337551763 2 1 0.000595238095238095 1680 17224 283358 B4GALNT3 GO:0043682 copper-transporting ATPase activity 0.185568024515725 -1.6843337551763 2 1 0.000595238095238095 1680 17224 540 ATP7B GO:0003858 3-hydroxybutyrate dehydrogenase activity 0.185568024515725 -1.6843337551763 2 1 0.000595238095238095 1680 17224 56898 BDH2 GO:0036505 prosaposin receptor activity 0.185568024515725 -1.6843337551763 2 1 0.000595238095238095 1680 17224 2861 GPR37 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity 0.185568024515725 -1.6843337551763 2 1 0.000595238095238095 1680 17224 4245 MGAT1 GO:0047322 [hydroxymethylglutaryl-CoA reductase (NADPH)] kinase activity 0.185568024515725 -1.6843337551763 2 1 0.000595238095238095 1680 17224 5563 PRKAA2 GO:0004825 methionine-tRNA ligase activity 0.185568024515725 -1.6843337551763 2 1 0.000595238095238095 1680 17224 4141 MARS GO:0015375 glycine:sodium symporter activity 0.185568024515725 -1.6843337551763 2 1 0.000595238095238095 1680 17224 6536 SLC6A9 GO:0070704 sterol desaturase activity 0.185568024515725 -1.6843337551763 2 1 0.000595238095238095 1680 17224 3992 FADS1 GO:0016603 glutaminyl-peptide cyclotransferase activity 0.185568024515725 -1.6843337551763 2 1 0.000595238095238095 1680 17224 54814 QPCTL GO:0004315 3-oxoacyl-[acyl-carrier-protein] synthase activity 0.185568024515725 -1.6843337551763 2 1 0.000595238095238095 1680 17224 2194 FASN GO:0004611 phosphoenolpyruvate carboxykinase activity 0.185568024515725 -1.6843337551763 2 1 0.000595238095238095 1680 17224 5106 PCK2 GO:0033872 [heparan sulfate]-glucosamine 3-sulfotransferase 3 activity 0.185568024515725 -1.6843337551763 2 1 0.000595238095238095 1680 17224 9953 HS3ST3B1 GO:0003994 aconitate hydratase activity 0.185568024515725 -1.6843337551763 2 1 0.000595238095238095 1680 17224 48 ACO1 GO:0019202 amino acid kinase activity 0.185568024515725 -1.6843337551763 2 1 0.000595238095238095 1680 17224 123688 HYKK GO:0016898 oxidoreductase activity, acting on the CH-OH group of donors, cytochrome as acceptor 0.185568024515725 -1.6843337551763 2 1 0.000595238095238095 1680 17224 197257 LDHD GO:0016420 malonyltransferase activity 0.185568024515725 -1.6843337551763 2 1 0.000595238095238095 1680 17224 2194 FASN GO:0005163 nerve growth factor receptor binding 0.185568024515725 -1.6843337551763 2 1 0.000595238095238095 1680 17224 27018 BEX3 GO:0047757 chondroitin-glucuronate 5-epimerase activity 0.185568024515725 -1.6843337551763 2 1 0.000595238095238095 1680 17224 92126 DSEL GO:0005287 high-affinity basic amino acid transmembrane transporter activity 0.185568024515725 -1.6843337551763 2 1 0.000595238095238095 1680 17224 6542 SLC7A2 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific) 0.185568024515725 -1.6843337551763 2 1 0.000595238095238095 1680 17224 10765 KDM5B GO:0070026 nitric oxide binding 0.185568024515725 -1.6843337551763 2 1 0.000595238095238095 1680 17224 875 CBS GO:0005295 neutral amino acid:sodium symporter activity 0.185568024515725 -1.6843337551763 2 1 0.000595238095238095 1680 17224 6536 SLC6A9 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity 0.185568024515725 -1.6843337551763 2 1 0.000595238095238095 1680 17224 5153 PDE1B GO:0032089 NACHT domain binding 0.185568024515725 -1.6843337551763 2 1 0.000595238095238095 1680 17224 10626 TRIM16 GO:0005006 epidermal growth factor-activated receptor activity 0.185568024515725 -1.6843337551763 2 1 0.000595238095238095 1680 17224 2202 EFEMP1 GO:0098960 postsynaptic neurotransmitter receptor activity 0.190532212337203 -1.65793400507649 40 6 0.00357142857142857 1680 17224 2566,8973,2900,1138,2898,2894 GABRG2,CHRNA6,GRIK4,CHRNA5,GRIK2,GRID1 GO:0017046 peptide hormone binding 0.190532212337203 -1.65793400507649 40 6 0.00357142857142857 1680 17224 10203,30061,5021,90,3480,2690 CALCRL,SLC40A1,OXTR,ACVR1,IGF1R,GHR GO:0019205 nucleobase-containing compound kinase activity 0.197015825490957 -1.62447122102922 49 7 0.00416666666666667 1680 17224 205,203,1740,129607,4354,260425,4355 AK4,AK1,DLG2,CMPK2,MPP1,MAGI3,MPP2 GO:0005102 signaling receptor binding 0.197661136212597 -1.62120114773231 1479 154 0.0916666666666667 1680 17224 2258,10859,3512,2625,50810,253559,6777,79094,5578,92737,1890,7049,3690,7099,1363,9353,5159,10188,1285,8838,7039,8822,2770,3626,5167,51704,2081,153,135112,649,10512,7292,10891,9863,84978,1948,10501,3958,2335,1962,5789,3655,65997,53342,2202,1123,3480,10505,23767,4040,23426,2674,8643,627,2660,153579,11001,9455,1944,2274,3092,6604,7060,1435,1015,83729,11247,51162,10371,4681,685,5071,27344,10580,3600,9495,10584,821,9378,10464,1794,10579,65055,9053,153090,5144,8321,9846,2241,23532,79924,22941,2257,57502,7481,5919,2444,83700,2260,23710,4088,8660,3627,10718,5795,2995,27018,5579,100506013,3673,9966,2887,3082,3977,114336,54550,57088,9235,3489,9826,2888,80381,8325,152189,4038,10673,5028,2621,5585,654,4734,8614,4091,9840,6850,2242,80329,7424,10451,2946,5829,3164,9693,10399,10333,22943,9454,64324,2268,1896,2200,2775,1740,652 FGF13,LILRB1,JCHAIN,GATA3,HDGFL3,CADM2,STAT5B,CHAC1,PRKCA,DNER,TYMP,TGFBR3,ITGB3,TLR4,CPE,SLIT2,PDGFRB,TNK2,COL4A3,WISP3,TGFA,FGF17,GNAI1,INHBC,ENPP1,GPRC5B,ERN1,ADRB1,NCOA7,BMP1,SEMA3C,TNFSF4,PPARGC1A,MAGI2,FRMD5,EFNB2,SEMA6B,LGALS3,FN1,EHHADH,PTPRD,ITGA6,RASL11B,IL17D,EFEMP1,CHN1,IGF1R,SEMA4F,FLRT3,LRP6,GRIP1,GFRA1,PTCH2,BDNF,MSTN,BTNL9,SLC27A2,HOMER2,EFNA3,FHL2,HIP1,SMARCD3,THBS4,CSF1,CDH17,INHBE,NXPH4,EGFL7,SEMA3A,NBL1,BTC,PRKN,PCSK1N,SORBS1,IL15,AKAP5,COLEC10,CANX,NRXN1,PIBF1,DOCK2,TACC2,REEP1,MAP7,DAB2IP,PDE4D,FZD1,GAB2,FER,PRAME,ADM2,SHANK2,FGF12,NLGN4X,WNT11,RARRES2,FRK,JAM3,FGFR1,GABARAPL1,SMAD3,IRS2,CXCL10,NRG3,PTPRJ,GYPC,BEX3,PRKCB,APELA,ITGA2,TNFSF15,GRB10,HGF,LIFR,CGB2,NECAB2,PLSCR4,IL32,IGFBP6,ARHGEF11,GRB14,CD276,FZD8,CMTM8,LRP4,TNFSF13B,P2RY1,GAS6,PKN1,BMP6,NEDD4,STC2,SMAD6,TESPA1,SYK,FES,ULBP1,VEGFC,VAV3,GSTM2,PXN,NR4A1,RAPGEF2,RACK1,TLR6,DKK1,HOMER3,NSD1,FGR,EDA,FBN1,GNAO1,DLG2,BMP4 GO:0031489 myosin V binding 0.200246634810296 -1.60820549811722 16 3 0.00178571428571429 1680 17224 5865,5874,51560 RAB3B,RAB27B,RAB6B GO:0070403 NAD+ binding 0.200246634810296 -1.60820549811722 16 3 0.00178571428571429 1680 17224 3248,83666,51084 HPGD,PARP9,CRYL1 GO:0004114 3',5'-cyclic-nucleotide phosphodiesterase activity 0.201555299501466 -1.60169149603372 24 4 0.00238095238095238 1680 17224 5151,5144,5153,10846 PDE8A,PDE4D,PDE1B,PDE10A GO:0015145 monosaccharide transmembrane transporter activity 0.201555299501466 -1.60169149603372 24 4 0.00238095238095238 1680 17224 154091,148808,114134,11182 SLC2A12,MFSD4A,SLC2A13,SLC2A6 GO:0022853 active ion transmembrane transporter activity 0.202933429433785 -1.59487728754613 67 9 0.00535714285714286 1680 17224 90423,481,10257,92270,10396,540,493,490,478 ATP6V1E2,ATP1B1,ABCC4,ATP6AP1L,ATP8A1,ATP7B,ATP2B4,ATP2B1,ATP1A3 GO:0042625 ATPase coupled ion transmembrane transporter activity 0.202933429433785 -1.59487728754613 67 9 0.00535714285714286 1680 17224 90423,481,10257,540,92270,10396,493,490,478 ATP6V1E2,ATP1B1,ABCC4,ATP7B,ATP6AP1L,ATP8A1,ATP2B4,ATP2B1,ATP1A3 GO:0035004 phosphatidylinositol 3-kinase activity 0.203841683583078 -1.59041164729631 76 10 0.00595238095238095 1680 17224 2264,8660,685,118788,3082,5287,8822,4233,5159,2260 FGFR4,IRS2,BTC,PIK3AP1,HGF,PIK3C2B,FGF17,MET,PDGFRB,FGFR1 GO:0038024 cargo receptor activity 0.203914998999051 -1.59005204354292 85 11 0.00654761904761905 1680 17224 5167,8492,619207,3949,7436,91179,4481,3092,4040,84171,29967 ENPP1,PRSS12,SCART1,LDLR,VLDLR,SCARF2,MSR1,HIP1,LRP6,LOXL4,LRP12 GO:0003824 catalytic activity 0.20513433727914 -1.58409021066083 5888 590 0.351190476190476 1680 17224 727936,161823,5153,8492,10157,51175,200810,1488,6777,79094,57406,54855,767,2070,81567,114907,7049,1768,158584,5911,25837,5521,87769,114818,1363,151230,120892,9200,253827,1244,8822,2161,377677,5831,5167,540,226,56898,2073,148252,22876,144132,51084,833,26524,1573,9748,25825,200558,84171,80216,6489,55137,26002,178,1131,3156,3992,4860,4651,4259,84159,2194,256435,51390,715,55760,57494,119391,9508,54814,126433,92170,170685,685,26052,79783,79695,11226,720,4430,84945,5596,2870,10584,114112,1040,8611,8564,399818,10840,64219,379,5874,1767,54961,91807,2617,2597,84650,153830,5208,27133,107,92370,23682,444,2260,260425,254042,8660,953,10400,8821,5066,5033,440138,200150,401265,27314,23464,23621,875,5585,2047,26262,3157,4646,2242,83666,26873,171425,51560,83401,205,23250,5788,2591,57761,64324,5352,64748,10000,2775,79644,79858,138429,3098,129607,8945,493,7093,90693,349565,23321,445,146664,8153,11328,6196,51166,7881,54504,3690,144110,744,2023,79605,6520,2651,4139,10257,284161,8612,27244,64943,114088,9149,8974,2081,5287,143384,58528,266722,7301,5563,91694,84959,65997,5217,80055,2202,285671,2589,56952,3480,23461,590,10846,8139,222537,112,9443,25827,55711,5058,56896,56901,2264,337876,11043,145173,11001,81790,11282,1944,55437,84033,5151,197257,9261,5337,79845,79646,4311,5071,54947,64131,11237,4916,23046,64900,9920,91351,1592,10247,3422,64429,140469,254887,22989,57110,1491,7846,7390,79875,59336,48,54941,9446,2444,64850,5903,5795,154214,5754,2633,4128,5802,3082,5413,129642,23324,8444,659,90293,57144,645,51655,56978,84749,10690,23551,2963,6446,5106,2098,6850,490,23491,5046,1843,9645,5509,389643,81788,23483,9941,4255,27293,23576,2329,1740,745,9536,23095,57530,23077,90,196463,347404,1850,10396,11174,5578,5881,16,8428,143279,5891,1890,27143,4714,2947,2731,54332,130399,26249,160428,56062,9829,27351,93,79683,2770,57630,133121,57089,10769,649,8707,92126,5603,8829,3636,241,1962,5789,6480,1718,55301,51477,55008,122622,1780,26038,57462,2122,26301,118788,6307,57143,5592,119587,375449,220441,5768,23127,7468,8476,23236,747,4324,29941,57161,51626,4355,6713,1717,64754,270,6296,2042,5321,6785,9781,29984,6768,1147,83594,780,9372,10290,440,55603,230,9805,5144,92270,2628,1787,8875,8708,5163,51700,53354,57502,5588,481,57205,6622,3669,5579,6999,84451,3248,9953,657,9474,5602,4281,57531,4642,10079,51191,402,3800,3628,81544,4734,80853,348751,8435,4245,23678,5593,85007,9896,79659,79603,55964,10924,9331,5210,217,2946,123688,56895,4354,5783,158866,7347,2977,2822,2268,7015,283209,79705,10715,11285,200035,478,7368,4598,2180,3798,7358,11099,18,63874,9486,51303,2152,23475,113622,10382,1595,22843,2051,374378,5791,5567,5159,1545,51062,10188,83667,23670,726,4919,10110,22838,157,203,10855,5125,84706,10090,55034,9886,283310,26272,79993,284716,285440,90423,114805,6319,22856,26227,50862,220213,760,1938,57552,4846,93974,23433,2948,80267,1852,64409,64077,639,283358,144193,26872,26035,11031,3099,5799,161436,152110,57520,83852,56605,8555,83694,92,55240,2272,130752,4233,3306,144245,57628,2241,25801,10076,5777,4597,79739,201161,27010,7453,89782,60468,360200,142679,113612,55819,5723,22983,23043,10279,2026,221078,79008,147111,5580,115123,10612,79758,26034,22800,55033,5865,9099,10765,51232,55753,116986,4141,79834,79623,9227,170691,283417,138151,390,5608,5547,340485,1515,55605,2669,114804,51776,4325,9619 GXYLT2,ADAL,PDE1B,PRSS12,AASS,TUBE1,ALG1L,CTBP2,STAT5B,CHAC1,ABHD6,TENT5C,CA8,EYA4,TXNDC5,FBXO32,TGFBR3,DNAH6,FAAH2,RAP2A,RAB26,PPP2R2B,GGACT,KLHL29,CPE,KLHL23,LRRK2,HACD1,MSRB3,ABCC2,FGF17,F12,CA13,PYCR1,ENPP1,ATP7B,ALDOA,BDH2,ERCC5,DIRAS1,INPP5F,DNHD1,CRYL1,CARS,LATS2,CYP2J2,SLK,BACE2,APLF,LOXL4,ALPK1,ST8SIA1,FIGN,MOXD1,AGL,CHRM3,HMGCR,FADS1,PNP,MYO10,MGST3,ARID5B,FASN,ST6GALNAC3,AIG1,C1R,DHX32,RIMKLB,GSTO2,ADAMTS3,QPCTL,FBXO27,MTG1,NUDT10,BTC,DNM3,SUGCT,GALNT12,GALNT6,C4A,MYO1B,ABHD13,MAPK4,GRK6,COLEC10,TXNRD3,CDS1,PLPP1,KMO,EEF1AKMT2,ALDH1L1,PJA1,ARL4D,RAB27B,DNAH5,SSH3,MYLK3,GARS,GAPDH,EBPL,RNF145,PFKFB2,KCNH5,ADCY1,PXYLP1,RAB38,ASPH,FGFR1,MAGI3,METAP1D,IRS2,ENTPD1,PEMT,INPP4B,PAM,P4HA1,ALG11,PLD5,KLHL31,RAB30,GCAT,BACE1,CBS,PKN1,EPHB1,TSPAN17,HMGCS1,MYO6,FES,PARP9,OPLAH,CLYBL,RAB6B,ELOVL3,AK4,ATP11A,PTPRC,GALNT3,TRIB3,NSD1,PLOD2,PLPPR2,AKT3,GNAO1,SRD5A3,NEK11,PIP5KL1,HK1,CMPK2,BTRC,ATP2B4,TLL2,CCDC126,NMNAT3,TRIM2,ASS1,MGAT5B,RND2,FKBP9,RPS6KA2,AADAT,KCNAB1,CPVL,ITGB3,TMEM86A,MPPED2,ENO1,PGBD5,SLC3A2,GCNT2,MARK1,ABCC4,GDPD1,PLPP2,SESN1,NT5DC2,TRIM9,DYRK1B,P4HA2,ERN1,PIK3C2B,CACUL1,RRAGD,HS6ST3,TYRO3,PRKAA2,LONRF1,UBASH3B,RASL11B,PFN2,PGAP1,EFEMP1,RNF180,GALNT1,PRTFDC1,IGF1R,ABCA5,BCHE,PDE10A,GAN,HS3ST5,ADCY6,MED7,FBXL2,FAR2,PAK1,DPYSL5,NDUFA4L2,FGFR4,CHSY3,MID2,B3GLCT,SLC27A2,RNF170,MGAT4B,EFNA3,STRADB,OBSCN,PDE8A,LDHD,MAPKAPK2,PLD1,RNF122,PANK3,MME,PRKN,LPCAT2,XYLT1,RNF24,NTRK3,KIF21B,LPIN3,KBTBD11,DDX60L,CYP26A1,RIDA,IDI1,ZDHHC6,MYO3B,ZDHHC23,MYH15,HRASLS,CTH,TUBA1A,UROS,THSD4,PRDM13,ACO1,RNF125,GSTO1,FRK,ETNPPL,RANBP2,PTPRJ,RNF217,PTK7,GBP1,MAOA,PTPRS,HGF,SEPT5,MBOAT2,MAN2B2,DYRK3,BMPR2,KLHL13,PAK5,BLVRB,RASD1,PRDM8,USP30,FUT9,RASD2,GTF2F2,SGK1,PCK2,ESD,SYK,ATP2B1,CES3,PCSK6,DUSP1,MICAL2,PPP1R3D,NUGGC,NUAK2,TGDS,EXOG,MGMT,SMPDL3B,DDAH1,FMO4,DLG2,MYRF,PTGES,KIF1B,CGN,MYCBP2,ACVR1,PLBD2,LANCL3,DUSP8,ATP8A1,ADAMTS6,PRKCA,RAC3,AARS,STK24,HECTD2,MOK,TYMP,PALD1,NDUFB8,GSTM3,GLDC,GDAP1,ACVR1C,KLHL3,ALDH1L2,KLHL4,DNAJC6,DESI1,ACVR2B,ZDHHC14,GNAI1,SH3RF1,ENPP6,ENTPD7,PLK2,BMP1,B3GALT2,DSEL,MAPK13,NRP1,INPPL1,ALOX5AP,EHHADH,PTPRD,ST6GAL1,DHCR24,OLAH,ISYNA1,HERC6,ADSSL1,DYNC1I1,CHD5,MYORG,MECOM,GBGT1,PIK3AP1,MSMO1,ADCK1,PRKG1,CPXM2,MAST4,RNF152,QSOX1,COLGALT2,NSD2,CDC42BPA,PLCB1,DAGLA,MMP15,PKN3,PELI2,DYNC2LI1,MPP2,SQLE,DHCR7,SMYD3,AMPD1,ACSM3,EPHA3,PLA2G4A,ELOVL4,RNF144A,RHOD,ST14,CHUK,NUDT12,DDR1,ZFYVE9,SPEG,ASNS,TENT5A,ALDOC,SCRN1,PDE4D,ATP6AP1L,GATM,TRDMT1,VNN2,B3GALT1,PDK1,CYB5R2,PANK1,NLGN4X,PRKCQ,ATP1B1,ATP10D,SNCA,ISG20,PRKCB,TDO2,MAP3K21,HPGD,HS3ST3B1,BMPR1A,ATG5,MAPK10,MID1,HACE1,MYO1D,ATP9A,HERC5,ARL2,KIF5C,INPP1,GDPD5,NEDD4,KDM7A,FTCDNL1,SOAT2,MGAT1,SGK3,PRKG2,PHYKPL,FIG4,DYNC2H1,CERS4,SEPT3,SMPDL3A,B4GALT6,PFKFB4,ALDH2,GSTM2,HYKK,AGPAT4,MPP1,PTPN13,ZDHHC15,UCHL3,GUCY1A2,GPLD1,FGR,TERT,PGM2L1,LRRK1,CERS1,B4GALT7,NUDT17,ATP1A3,UGT8,MVK,ACSL1,KIF5A,UGDH,PTPN21,ABAT,ABHD4,CHST10,FKBP11,F3,QPRT,ADPRHL1,TUBB4A,CYP51A1,PPM1E,EPHB6,GALNT18,PTPRE,PRKACB,PDGFRB,CYP1B1,ATL1,TNK2,SESN2,CEMIP2,CAPN5,ROR1,SGK2,RNF44,GRK3,AK1,HPSE,PCSK5,GPT2,UST,MOCOS,RHOBTB1,OTOGL,FBXO4,ELOVL7,RIMKLA,CYP4V2,ATP6V1E2,GALNT13,SCD,CHSY1,PHGDH,RNF141,OTUD1,CA2,EEF2,NCEH1,NOS3,ATP5IF1,RHOQ,GSTM4,EDEM3,DUSP9,GALNT17,LHPP,PRDM1,B4GALNT3,AMDHD1,STEAP1,GLCE,RAB31,HK2,PTPRN2,EML5,NEK10,HECW2,SETDB2,ERO1B,CDC14B,RPS6KL1,ACVR2A,STEAP3,FHIT,MDH1B,MET,HSPA2,ALG10B,DPP10,FER,GCA,PTPRU,PTPN6,MVD,TTLL7,CENPV,TPK1,WARS,LMLN,BACH2,TMPRSS9,DUSP19,CYP2U1,RNF130,PSPH,MAST1,TNIK,PRSS16,ENO2,NSUN6,SLX1B,NOTUM,PRKCD,MARCH3,TRIM3,DHRS12,IPCEF1,RRAS2,FKBP14,RAB3B,USP2,KDM5B,CRIM1,OGDHL,AGAP2,MARS,PEAK1,GALNT14,LRAT,ADAMTS17,DPY19L2,NACC2,RND3,MAP2K6,PRCP,ACER2,CTSV,KIF21A,GEM,RNF157,MAP3K20,MMP16,ABCG1 GO:0004860 protein kinase inhibitor activity 0.213623235166147 -1.54354139894436 95 12 0.00714285714285714 1680 17224 55450,57761,5611,23767,142679,4869,5577,10399,10253,54997,2810,5569 CAMK2N1,TRIB3,DNAJC3,FLRT3,DUSP19,NPM1,PRKAR2B,RACK1,SPRY2,TESC,SFN,PKIA GO:0019003 GDP binding 0.213983206641446 -1.54185774067761 59 8 0.00476190476190476 1680 17224 5865,2633,5911,11031,5874,2669,2770,58528 RAB3B,GBP1,RAP2A,RAB31,RAB27B,GEM,GNAI1,RRAGD GO:0005546 phosphatidylinositol-4,5-bisphosphate binding 0.215168503414556 -1.53633382100391 68 9 0.00535714285714286 1680 17224 4139,115548,29091,4430,3092,5217,23236,1687,85477 MARK1,FCHO2,STXBP6,MYO1B,HIP1,PFN2,PLCB1,GSDME,SCIN GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity 0.215168503414556 -1.53633382100391 68 9 0.00535714285714286 1680 17224 2264,8660,685,118788,3082,8822,4233,5159,2260 FGFR4,IRS2,BTC,PIK3AP1,HGF,FGF17,MET,PDGFRB,FGFR1 GO:0047144 2-acylglycerol-3-phosphate O-acyltransferase activity 0.216683867576602 -1.5293158190966 9 2 0.00119047619047619 1680 17224 129642,54947 MBOAT2,LPCAT2 GO:0035252 UDP-xylosyltransferase activity 0.216683867576602 -1.5293158190966 9 2 0.00119047619047619 1680 17224 727936,64131 GXYLT2,XYLT1 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly 0.216683867576602 -1.5293158190966 9 2 0.00119047619047619 1680 17224 6875,117154 TAF4B,DACH2 GO:0004017 adenylate kinase activity 0.216683867576602 -1.5293158190966 9 2 0.00119047619047619 1680 17224 205,203 AK4,AK1 GO:0004862 cAMP-dependent protein kinase inhibitor activity 0.216683867576602 -1.5293158190966 9 2 0.00119047619047619 1680 17224 5577,5569 PRKAR2B,PKIA GO:0004716 signal transducer, downstream of receptor, with protein tyrosine kinase activity 0.216683867576602 -1.5293158190966 9 2 0.00119047619047619 1680 17224 7301,6850 TYRO3,SYK GO:0042285 xylosyltransferase activity 0.216683867576602 -1.5293158190966 9 2 0.00119047619047619 1680 17224 727936,64131 GXYLT2,XYLT1 GO:0005024 transforming growth factor beta-activated receptor activity 0.216683867576602 -1.5293158190966 9 2 0.00119047619047619 1680 17224 90,7049 ACVR1,TGFBR3 GO:0015245 fatty acid transmembrane transporter activity 0.216683867576602 -1.5293158190966 9 2 0.00119047619047619 1680 17224 11001,84879 SLC27A2,MFSD2A GO:0008381 mechanosensitive ion channel activity 0.216683867576602 -1.5293158190966 9 2 0.00119047619047619 1680 17224 27112,728215 FAM155B,FAM155A GO:0031545 peptidyl-proline 4-dioxygenase activity 0.216683867576602 -1.5293158190966 9 2 0.00119047619047619 1680 17224 5033,8974 P4HA1,P4HA2 GO:0008429 phosphatidylethanolamine binding 0.216683867576602 -1.5293158190966 9 2 0.00119047619047619 1680 17224 5360,10400 PLTP,PEMT GO:0055056 D-glucose transmembrane transporter activity 0.216683867576602 -1.5293158190966 9 2 0.00119047619047619 1680 17224 154091,11182 SLC2A12,SLC2A6 GO:0043560 insulin receptor substrate binding 0.216683867576602 -1.5293158190966 9 2 0.00119047619047619 1680 17224 3480,5580 IGF1R,PRKCD GO:0031681 G-protein beta-subunit binding 0.216683867576602 -1.5293158190966 9 2 0.00119047619047619 1680 17224 6000,23551 RGS7,RASD2 GO:0003857 3-hydroxyacyl-CoA dehydrogenase activity 0.216683867576602 -1.5293158190966 9 2 0.00119047619047619 1680 17224 1962,51084 EHHADH,CRYL1 GO:0016832 aldehyde-lyase activity 0.216683867576602 -1.5293158190966 9 2 0.00119047619047619 1680 17224 230,226 ALDOC,ALDOA GO:0032813 tumor necrosis factor receptor superfamily binding 0.222192717974874 -1.50421017470394 42 6 0.00357142857142857 1680 17224 9966,153090,7292,1896,27018,10673 TNFSF15,DAB2IP,TNFSF4,EDA,BEX3,TNFSF13B GO:0050681 androgen receptor binding 0.222192717974874 -1.50421017470394 42 6 0.00357142857142857 1680 17224 23426,64324,5585,10891,5579,2274 GRIP1,NSD1,PKN1,PPARGC1A,PRKCB,FHL2 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding 0.222790758216709 -1.50152225196569 25 4 0.00238095238095238 1680 17224 3092,285590,134829,54477 HIP1,SH3PXD2B,CLVS2,PLEKHA5 GO:0004112 cyclic-nucleotide phosphodiesterase activity 0.222790758216709 -1.50152225196569 25 4 0.00238095238095238 1680 17224 5151,5144,5153,10846 PDE8A,PDE4D,PDE1B,PDE10A GO:0016879 ligase activity, forming carbon-nitrogen bonds 0.225861883988704 -1.48783159932096 51 7 0.00416666666666667 1680 17224 445,93974,440,57494,122622,79739,284716 ASS1,ATP5IF1,ASNS,RIMKLB,ADSSL1,TTLL7,RIMKLA GO:0005283 amino acid:sodium symporter activity 0.226720718658738 -1.48403633323737 17 3 0.00178571428571429 1680 17224 55117,6536,6507 SLC6A15,SLC6A9,SLC1A3 GO:0004383 guanylate cyclase activity 0.226720718658738 -1.48403633323737 17 3 0.00178571428571429 1680 17224 112,2977,107 ADCY6,GUCY1A2,ADCY1 GO:0051371 muscle alpha-actinin binding 0.226720718658738 -1.48403633323737 17 3 0.00178571428571429 1680 17224 9172,171024,23022 MYOM2,SYNPO2,PALLD GO:0097493 structural molecule activity conferring elasticity 0.226720718658738 -1.48403633323737 17 3 0.00178571428571429 1680 17224 9172,2200,84034 MYOM2,FBN1,EMILIN2 GO:0004550 nucleoside diphosphate kinase activity 0.226720718658738 -1.48403633323737 17 3 0.00178571428571429 1680 17224 205,203,129607 AK4,AK1,CMPK2 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor 0.226720718658738 -1.48403633323737 17 3 0.00178571428571429 1680 17224 4128,84171,389643 MAOA,LOXL4,NUGGC GO:0008375 acetylglucosaminyltransferase activity 0.227441375216209 -1.48086276515658 60 8 0.00476190476190476 1680 17224 90693,2651,8708,4245,64131,11282,8707,146664 CCDC126,GCNT2,B3GALT1,MGAT1,XYLT1,MGAT4B,B3GALT2,MGAT5B GO:0031406 carboxylic acid binding 0.231842351064635 -1.46169765956817 200 23 0.0136904761904762 1680 17224 83667,241,23670,445,6507,63827,27244,9227,16,1592,6622,10247,23576,3399,348751,5352,6999,8974,2172,5066,5033,2731,4846 SESN2,ALOX5AP,CEMIP2,ASS1,SLC1A3,BCAN,SESN1,LRAT,AARS,CYP26A1,SNCA,RIDA,DDAH1,ID3,FTCDNL1,PLOD2,TDO2,P4HA2,FABP6,PAM,P4HA1,GLDC,NOS3 GO:0042056 chemoattractant activity 0.233474714509158 -1.45468149677688 34 5 0.00297619047619048 1680 17224 7424,3082,652,10584,3958 VEGFC,HGF,BMP4,COLEC10,LGALS3 GO:0030544 Hsp70 protein binding 0.233474714509158 -1.45468149677688 34 5 0.00297619047619048 1680 17224 2861,5071,4597,2081,6622 GPR37,PRKN,MVD,ERN1,SNCA GO:0001786 phosphatidylserine binding 0.238634896670244 -1.43282052406028 43 6 0.00357142857142857 1680 17224 2621,4139,115548,114879,10125,85477 GAS6,MARK1,FCHO2,OSBPL5,RASGRP1,SCIN GO:0042165 neurotransmitter binding 0.240802469124822 -1.42377831175942 52 7 0.00416666666666667 1680 17224 8973,875,3363,1138,590,1131,2731 CHRNA6,CBS,HTR7,CHRNA5,BCHE,CHRM3,GLDC GO:0035326 enhancer binding 0.242492508443411 -1.41678446209866 107 13 0.00773809523809524 1680 17224 4088,9242,4487,55893,60468,2624,5966,7494,619279,4779,2625,3239,4208 SMAD3,MSC,MSX1,ZNF395,BACH2,GATA2,REL,XBP1,ZNF704,NFE2L1,GATA3,HOXD13,MEF2C GO:0019707 protein-cysteine S-acyltransferase activity 0.244570435280901 -1.40825193269547 26 4 0.00238095238095238 1680 17224 79683,64429,158866,254887 ZDHHC14,ZDHHC6,ZDHHC15,ZDHHC23 GO:0090079 translation regulator activity, nucleic acid binding 0.244570435280901 -1.40825193269547 26 4 0.00238095238095238 1680 17224 400961,64506,23367,9811 PAIP2B,CPEB1,LARP1,CTIF GO:0019706 protein-cysteine S-palmitoyltransferase activity 0.244570435280901 -1.40825193269547 26 4 0.00238095238095238 1680 17224 79683,64429,158866,254887 ZDHHC14,ZDHHC6,ZDHHC15,ZDHHC23 GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor 0.25232407110468 -1.37704102120876 35 5 0.00297619047619048 1680 17224 2597,217,55711,160428,10840 GAPDH,ALDH2,FAR2,ALDH1L2,ALDH1L1 GO:0019207 kinase regulator activity 0.252900287194777 -1.37475998970078 222 25 0.0148809523809524 1680 17224 92597,2258,5611,4869,5577,7481,2621,10399,7453,55450,57761,3627,10718,51704,3071,154043,23767,142679,4040,84632,26034,54997,10253,5569,2810 MOB1B,FGF13,DNAJC3,NPM1,PRKAR2B,WNT11,GAS6,RACK1,WARS,CAMK2N1,TRIB3,CXCL10,NRG3,GPRC5B,NCKAP1L,CNKSR3,FLRT3,DUSP19,LRP6,AFAP1L2,IPCEF1,TESC,SPRY2,PKIA,SFN GO:0052813 phosphatidylinositol bisphosphate kinase activity 0.25348425476519 -1.37245356925981 71 9 0.00535714285714286 1680 17224 2264,8660,685,118788,3082,8822,4233,5159,2260 FGFR4,IRS2,BTC,PIK3AP1,HGF,FGF17,MET,PDGFRB,FGFR1 GO:0071837 HMG box domain binding 0.253800484165002 -1.37120681604015 18 3 0.00178571428571429 1680 17224 2625,5455,4208 GATA3,POU3F3,MEF2C GO:0042166 acetylcholine binding 0.253800484165002 -1.37120681604015 18 3 0.00178571428571429 1680 17224 8973,1138,1131 CHRNA6,CHRNA5,CHRM3 GO:0005537 mannose binding 0.253800484165002 -1.37120681604015 18 3 0.00178571428571429 1680 17224 10960,10584,1203 LMAN2,COLEC10,CLN5 GO:0004016 adenylate cyclase activity 0.253800484165002 -1.37120681604015 18 3 0.00178571428571429 1680 17224 112,2977,107 ADCY6,GUCY1A2,ADCY1 GO:0035255 ionotropic glutamate receptor binding 0.253800484165002 -1.37120681604015 18 3 0.00178571428571429 1680 17224 1740,821,22941 DLG2,CANX,SHANK2 GO:0070300 phosphatidic acid binding 0.253800484165002 -1.37120681604015 18 3 0.00178571428571429 1680 17224 4139,5360,9693 MARK1,PLTP,RAPGEF2 GO:0036122 BMP binding 0.254364401135758 -1.36898738995012 10 2 0.00119047619047619 1680 17224 4681,659 NBL1,BMPR2 GO:0046624 sphingolipid transporter activity 0.254364401135758 -1.36898738995012 10 2 0.00119047619047619 1680 17224 83985,5360 SPNS1,PLTP GO:0015279 store-operated calcium channel activity 0.254364401135758 -1.36898738995012 10 2 0.00119047619047619 1680 17224 7220,7222 TRPC1,TRPC3 GO:0016723 oxidoreductase activity, oxidizing metal ions, NAD or NADP as acceptor 0.254364401135758 -1.36898738995012 10 2 0.00119047619047619 1680 17224 55240,26872 STEAP3,STEAP1 GO:0035612 AP-2 adaptor complex binding 0.254364401135758 -1.36898738995012 10 2 0.00119047619047619 1680 17224 3092,23682 HIP1,RAB38 GO:0043121 neurotrophin binding 0.254364401135758 -1.36898738995012 10 2 0.00119047619047619 1680 17224 4916,5046 NTRK3,PCSK6 GO:0017166 vinculin binding 0.254364401135758 -1.36898738995012 10 2 0.00119047619047619 1680 17224 10174,5829 SORBS3,PXN GO:0019203 carbohydrate phosphatase activity 0.254364401135758 -1.36898738995012 10 2 0.00119047619047619 1680 17224 5210,5208 PFKFB4,PFKFB2 GO:0030957 Tat protein binding 0.254364401135758 -1.36898738995012 10 2 0.00119047619047619 1680 17224 4869,23710 NPM1,GABARAPL1 GO:0043522 leucine zipper domain binding 0.254364401135758 -1.36898738995012 10 2 0.00119047619047619 1680 17224 468,1649 ATF4,DDIT3 GO:0050308 sugar-phosphatase activity 0.254364401135758 -1.36898738995012 10 2 0.00119047619047619 1680 17224 5210,5208 PFKFB4,PFKFB2 GO:0008514 organic anion transmembrane transporter activity 0.255639653328679 -1.36398643029283 232 26 0.0154761904761905 1680 17224 256987,6520,6536,206358,11001,120103,1244,6507,6542,10560,28232,6541,51310,23657,6567,84879,347735,8140,81796,220963,55117,55356,353189,6510,117247,8501 SERINC5,SLC3A2,SLC6A9,SLC36A1,SLC27A2,SLC36A4,ABCC2,SLC1A3,SLC7A2,SLC19A2,SLCO3A1,SLC7A1,SLC22A17,SLC7A11,SLC16A2,MFSD2A,SERINC2,SLC7A5,SLCO5A1,SLC16A9,SLC6A15,SLC22A15,SLCO4C1,SLC1A5,SLC16A10,SLC43A1 GO:0022834 ligand-gated channel activity 0.256192686009128 -1.36182543790074 146 17 0.0101190476190476 1680 17224 2898,2561,56704,55283,2894,2566,6262,8973,22821,3709,2570,255231,3761,2900,1138,41,2906 GRIK2,GABRB2,JPH1,MCOLN3,GRID1,GABRG2,RYR2,CHRNA6,RASA3,ITPR2,GABRR2,MCOLN2,KCNJ4,GRIK4,CHRNA5,ASIC1,GRIN2D GO:0015276 ligand-gated ion channel activity 0.256192686009128 -1.36182543790074 146 17 0.0101190476190476 1680 17224 2898,2561,56704,55283,2894,2566,6262,8973,22821,3709,2570,255231,3761,2900,1138,41,2906 GRIK2,GABRB2,JPH1,MCOLN3,GRID1,GABRG2,RYR2,CHRNA6,RASA3,ITPR2,GABRR2,MCOLN2,KCNJ4,GRIK4,CHRNA5,ASIC1,GRIN2D GO:0099094 ligand-gated cation channel activity 0.263597893803197 -1.33333046651015 109 13 0.00773809523809524 1680 17224 255231,2900,3761,1138,2898,56704,55283,41,8973,22821,6262,2906,3709 MCOLN2,GRIK4,KCNJ4,CHRNA5,GRIK2,JPH1,MCOLN3,ASIC1,CHRNA6,RASA3,RYR2,GRIN2D,ITPR2 GO:0008515 sucrose transmembrane transporter activity 0.26501557525862 -1.32796668016224 3 1 0.000595238095238095 1680 17224 85414 SLC45A3 GO:0031177 phosphopantetheine binding 0.26501557525862 -1.32796668016224 3 1 0.000595238095238095 1680 17224 2194 FASN GO:0031802 type 5 metabotropic glutamate receptor binding 0.26501557525862 -1.32796668016224 3 1 0.000595238095238095 1680 17224 54550 NECAB2 GO:0000026 alpha-1,2-mannosyltransferase activity 0.26501557525862 -1.32796668016224 3 1 0.000595238095238095 1680 17224 440138 ALG11 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential 0.26501557525862 -1.32796668016224 3 1 0.000595238095238095 1680 17224 783 CACNB2 GO:0016508 long-chain-enoyl-CoA hydratase activity 0.26501557525862 -1.32796668016224 3 1 0.000595238095238095 1680 17224 1962 EHHADH GO:0004992 platelet activating factor receptor activity 0.26501557525862 -1.32796668016224 3 1 0.000595238095238095 1680 17224 5159 PDGFRB GO:0017159 pantetheine hydrolase activity 0.26501557525862 -1.32796668016224 3 1 0.000595238095238095 1680 17224 8875 VNN2 GO:0030267 glyoxylate reductase (NADP) activity 0.26501557525862 -1.32796668016224 3 1 0.000595238095238095 1680 17224 1488 CTBP2 GO:0004566 beta-glucuronidase activity 0.26501557525862 -1.32796668016224 3 1 0.000595238095238095 1680 17224 10855 HPSE GO:0004500 dopamine beta-monooxygenase activity 0.26501557525862 -1.32796668016224 3 1 0.000595238095238095 1680 17224 26002 MOXD1 GO:0004768 stearoyl-CoA 9-desaturase activity 0.26501557525862 -1.32796668016224 3 1 0.000595238095238095 1680 17224 6319 SCD GO:0035663 Toll-like receptor 2 binding 0.26501557525862 -1.32796668016224 3 1 0.000595238095238095 1680 17224 10333 TLR6 GO:0102486 dCTP phosphohydrolase activity 0.26501557525862 -1.32796668016224 3 1 0.000595238095238095 1680 17224 953 ENTPD1 GO:0051032 nucleic acid transmembrane transporter activity 0.26501557525862 -1.32796668016224 3 1 0.000595238095238095 1680 17224 54847 SIDT1 GO:0047391 alkylglycerophosphoethanolamine phosphodiesterase activity 0.26501557525862 -1.32796668016224 3 1 0.000595238095238095 1680 17224 284161 GDPD1 GO:0097108 hedgehog family protein binding 0.26501557525862 -1.32796668016224 3 1 0.000595238095238095 1680 17224 8643 PTCH2 GO:0000254 C-4 methylsterol oxidase activity 0.26501557525862 -1.32796668016224 3 1 0.000595238095238095 1680 17224 6307 MSMO1 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity 0.26501557525862 -1.32796668016224 3 1 0.000595238095238095 1680 17224 2651 GCNT2 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity 0.26501557525862 -1.32796668016224 3 1 0.000595238095238095 1680 17224 3709 ITPR2 GO:0004514 nicotinate-nucleotide diphosphorylase (carboxylating) activity 0.26501557525862 -1.32796668016224 3 1 0.000595238095238095 1680 17224 23475 QPRT GO:0102485 dATP phosphohydrolase activity 0.26501557525862 -1.32796668016224 3 1 0.000595238095238095 1680 17224 953 ENTPD1 GO:0004939 beta-adrenergic receptor activity 0.26501557525862 -1.32796668016224 3 1 0.000595238095238095 1680 17224 153 ADRB1 GO:0004735 pyrroline-5-carboxylate reductase activity 0.26501557525862 -1.32796668016224 3 1 0.000595238095238095 1680 17224 5831 PYCR1 GO:0061628 H3K27me3 modified histone binding 0.26501557525862 -1.32796668016224 3 1 0.000595238095238095 1680 17224 26038 CHD5 GO:0033823 procollagen glucosyltransferase activity 0.26501557525862 -1.32796668016224 3 1 0.000595238095238095 1680 17224 5352 PLOD2 GO:0047192 1-alkylglycerophosphocholine O-acetyltransferase activity 0.26501557525862 -1.32796668016224 3 1 0.000595238095238095 1680 17224 54947 LPCAT2 GO:0016882 cyclo-ligase activity 0.26501557525862 -1.32796668016224 3 1 0.000595238095238095 1680 17224 93974 ATP5IF1 GO:0051033 RNA transmembrane transporter activity 0.26501557525862 -1.32796668016224 3 1 0.000595238095238095 1680 17224 54847 SIDT1 GO:0043812 phosphatidylinositol-4-phosphate phosphatase activity 0.26501557525862 -1.32796668016224 3 1 0.000595238095238095 1680 17224 9896 FIG4 GO:0031852 mu-type opioid receptor binding 0.26501557525862 -1.32796668016224 3 1 0.000595238095238095 1680 17224 2775 GNAO1 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity 0.26501557525862 -1.32796668016224 3 1 0.000595238095238095 1680 17224 11123 RCAN3 GO:0005169 neurotrophin TRKB receptor binding 0.26501557525862 -1.32796668016224 3 1 0.000595238095238095 1680 17224 627 BDNF GO:0034041 sterol-transporting ATPase activity 0.26501557525862 -1.32796668016224 3 1 0.000595238095238095 1680 17224 9619 ABCG1 GO:0008475 procollagen-lysine 5-dioxygenase activity 0.26501557525862 -1.32796668016224 3 1 0.000595238095238095 1680 17224 5352 PLOD2 GO:0004104 cholinesterase activity 0.26501557525862 -1.32796668016224 3 1 0.000595238095238095 1680 17224 590 BCHE GO:0060002 plus-end directed microfilament motor activity 0.26501557525862 -1.32796668016224 3 1 0.000595238095238095 1680 17224 4651 MYO10 GO:0051538 3 iron, 4 sulfur cluster binding 0.26501557525862 -1.32796668016224 3 1 0.000595238095238095 1680 17224 48 ACO1 GO:0033765 steroid dehydrogenase activity, acting on the CH-CH group of donors 0.26501557525862 -1.32796668016224 3 1 0.000595238095238095 1680 17224 79644 SRD5A3 GO:0001605 adrenomedullin receptor activity 0.26501557525862 -1.32796668016224 3 1 0.000595238095238095 1680 17224 10203 CALCRL GO:0004699 calcium-independent protein kinase C activity 0.26501557525862 -1.32796668016224 3 1 0.000595238095238095 1680 17224 5580 PRKCD GO:0047751 cholestenone 5-alpha-reductase activity 0.26501557525862 -1.32796668016224 3 1 0.000595238095238095 1680 17224 79644 SRD5A3 GO:0102490 8-oxo-dGTP phosphohydrolase activity 0.26501557525862 -1.32796668016224 3 1 0.000595238095238095 1680 17224 953 ENTPD1 GO:0008384 IkappaB kinase activity 0.26501557525862 -1.32796668016224 3 1 0.000595238095238095 1680 17224 1147 CHUK GO:0005119 smoothened binding 0.26501557525862 -1.32796668016224 3 1 0.000595238095238095 1680 17224 8643 PTCH2 GO:0008506 sucrose:proton symporter activity 0.26501557525862 -1.32796668016224 3 1 0.000595238095238095 1680 17224 85414 SLC45A3 GO:0071209 U7 snRNA binding 0.26501557525862 -1.32796668016224 3 1 0.000595238095238095 1680 17224 134353 LSM11 GO:0034711 inhibin binding 0.26501557525862 -1.32796668016224 3 1 0.000595238095238095 1680 17224 92 ACVR2A GO:0009041 uridylate kinase activity 0.26501557525862 -1.32796668016224 3 1 0.000595238095238095 1680 17224 129607 CMPK2 GO:0016215 acyl-CoA desaturase activity 0.26501557525862 -1.32796668016224 3 1 0.000595238095238095 1680 17224 6319 SCD GO:0017095 heparan sulfate 6-O-sulfotransferase activity 0.26501557525862 -1.32796668016224 3 1 0.000595238095238095 1680 17224 266722 HS6ST3 GO:0004833 tryptophan 2,3-dioxygenase activity 0.26501557525862 -1.32796668016224 3 1 0.000595238095238095 1680 17224 6999 TDO2 GO:0035651 AP-3 adaptor complex binding 0.26501557525862 -1.32796668016224 3 1 0.000595238095238095 1680 17224 23682 RAB38 GO:0050211 procollagen galactosyltransferase activity 0.26501557525862 -1.32796668016224 3 1 0.000595238095238095 1680 17224 23127 COLGALT2 GO:0015157 oligosaccharide transmembrane transporter activity 0.26501557525862 -1.32796668016224 3 1 0.000595238095238095 1680 17224 85414 SLC45A3 GO:0004924 oncostatin-M receptor activity 0.26501557525862 -1.32796668016224 3 1 0.000595238095238095 1680 17224 3977 LIFR GO:0016838 carbon-oxygen lyase activity, acting on phosphates 0.26501557525862 -1.32796668016224 3 1 0.000595238095238095 1680 17224 64850 ETNPPL GO:0005111 type 2 fibroblast growth factor receptor binding 0.26501557525862 -1.32796668016224 3 1 0.000595238095238095 1680 17224 8822 FGF17 GO:0019776 Atg8 ligase activity 0.26501557525862 -1.32796668016224 3 1 0.000595238095238095 1680 17224 9474 ATG5 GO:0101006 protein histidine phosphatase activity 0.26501557525862 -1.32796668016224 3 1 0.000595238095238095 1680 17224 64077 LHPP GO:0003865 3-oxo-5-alpha-steroid 4-dehydrogenase activity 0.26501557525862 -1.32796668016224 3 1 0.000595238095238095 1680 17224 79644 SRD5A3 GO:0102489 GTP phosphohydrolase activity 0.26501557525862 -1.32796668016224 3 1 0.000595238095238095 1680 17224 953 ENTPD1 GO:0004117 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity 0.26501557525862 -1.32796668016224 3 1 0.000595238095238095 1680 17224 5153 PDE1B GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity 0.26501557525862 -1.32796668016224 3 1 0.000595238095238095 1680 17224 10846 PDE10A GO:0051430 corticotropin-releasing hormone receptor 1 binding 0.26501557525862 -1.32796668016224 3 1 0.000595238095238095 1680 17224 2775 GNAO1 GO:0002060 purine nucleobase binding 0.26501557525862 -1.32796668016224 3 1 0.000595238095238095 1680 17224 4860 PNP GO:0004647 phosphoserine phosphatase activity 0.26501557525862 -1.32796668016224 3 1 0.000595238095238095 1680 17224 5723 PSPH GO:0008426 protein kinase C inhibitor activity 0.26501557525862 -1.32796668016224 3 1 0.000595238095238095 1680 17224 2810 SFN GO:1990756 protein binding, bridging involved in substrate recognition for ubiquitination 0.26501557525862 -1.32796668016224 3 1 0.000595238095238095 1680 17224 91947 ARRDC4 GO:1904121 phosphatidylethanolamine transporter activity 0.26501557525862 -1.32796668016224 3 1 0.000595238095238095 1680 17224 5360 PLTP GO:0050682 AF-2 domain binding 0.26501557525862 -1.32796668016224 3 1 0.000595238095238095 1680 17224 2104 ESRRG GO:0004605 phosphatidate cytidylyltransferase activity 0.26501557525862 -1.32796668016224 3 1 0.000595238095238095 1680 17224 1040 CDS1 GO:0005136 interleukin-4 receptor binding 0.26501557525862 -1.32796668016224 3 1 0.000595238095238095 1680 17224 10464 PIBF1 GO:0016971 flavin-linked sulfhydryl oxidase activity 0.26501557525862 -1.32796668016224 3 1 0.000595238095238095 1680 17224 5768 QSOX1 GO:0086077 gap junction channel activity involved in AV node cell-bundle of His cell electrical coupling 0.26501557525862 -1.32796668016224 3 1 0.000595238095238095 1680 17224 10052 GJC1 GO:0009669 sucrose:cation symporter activity 0.26501557525862 -1.32796668016224 3 1 0.000595238095238095 1680 17224 85414 SLC45A3 GO:0004517 nitric-oxide synthase activity 0.26501557525862 -1.32796668016224 3 1 0.000595238095238095 1680 17224 4846 NOS3 GO:0016909 SAP kinase activity 0.26501557525862 -1.32796668016224 3 1 0.000595238095238095 1680 17224 5602 MAPK10 GO:0047623 adenosine-phosphate deaminase activity 0.26501557525862 -1.32796668016224 3 1 0.000595238095238095 1680 17224 270 AMPD1 GO:0102488 dTTP phosphohydrolase activity 0.26501557525862 -1.32796668016224 3 1 0.000595238095238095 1680 17224 953 ENTPD1 GO:0102491 dGTP phosphohydrolase activity 0.26501557525862 -1.32796668016224 3 1 0.000595238095238095 1680 17224 953 ENTPD1 GO:0015234 thiamine transmembrane transporter activity 0.26501557525862 -1.32796668016224 3 1 0.000595238095238095 1680 17224 10560 SLC19A2 GO:0016618 hydroxypyruvate reductase activity 0.26501557525862 -1.32796668016224 3 1 0.000595238095238095 1680 17224 1488 CTBP2 GO:0035033 histone deacetylase regulator activity 0.26501557525862 -1.32796668016224 3 1 0.000595238095238095 1680 17224 6497 SKI GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity 0.26501557525862 -1.32796668016224 3 1 0.000595238095238095 1680 17224 11282 MGAT4B GO:0015307 drug:proton antiporter activity 0.26501557525862 -1.32796668016224 3 1 0.000595238095238095 1680 17224 5002 SLC22A18 GO:0019862 IgA binding 0.26501557525862 -1.32796668016224 3 1 0.000595238095238095 1680 17224 3512 JCHAIN GO:0000309 nicotinamide-nucleotide adenylyltransferase activity 0.26501557525862 -1.32796668016224 3 1 0.000595238095238095 1680 17224 349565 NMNAT3 GO:0003968 RNA-directed 5'-3' RNA polymerase activity 0.26501557525862 -1.32796668016224 3 1 0.000595238095238095 1680 17224 7015 TERT GO:0004165 dodecenoyl-CoA delta-isomerase activity 0.26501557525862 -1.32796668016224 3 1 0.000595238095238095 1680 17224 1962 EHHADH GO:0047374 methylumbelliferyl-acetate deacetylase activity 0.26501557525862 -1.32796668016224 3 1 0.000595238095238095 1680 17224 2098 ESD GO:0030158 protein xylosyltransferase activity 0.26501557525862 -1.32796668016224 3 1 0.000595238095238095 1680 17224 64131 XYLT1 GO:0001635 calcitonin gene-related peptide receptor activity 0.26501557525862 -1.32796668016224 3 1 0.000595238095238095 1680 17224 10203 CALCRL GO:0102487 dUTP phosphohydrolase activity 0.26501557525862 -1.32796668016224 3 1 0.000595238095238095 1680 17224 953 ENTPD1 GO:0005157 macrophage colony-stimulating factor receptor binding 0.26501557525862 -1.32796668016224 3 1 0.000595238095238095 1680 17224 1435 CSF1 GO:0050816 phosphothreonine residue binding 0.26501557525862 -1.32796668016224 3 1 0.000595238095238095 1680 17224 4734 NEDD4 GO:0033745 L-methionine-(R)-S-oxide reductase activity 0.26501557525862 -1.32796668016224 3 1 0.000595238095238095 1680 17224 253827 MSRB3 GO:0005017 platelet-derived growth factor-activated receptor activity 0.26501557525862 -1.32796668016224 3 1 0.000595238095238095 1680 17224 5159 PDGFRB GO:0015154 disaccharide transmembrane transporter activity 0.26501557525862 -1.32796668016224 3 1 0.000595238095238095 1680 17224 85414 SLC45A3 GO:0004813 alanine-tRNA ligase activity 0.26501557525862 -1.32796668016224 3 1 0.000595238095238095 1680 17224 16 AARS GO:0008427 calcium-dependent protein kinase inhibitor activity 0.26501557525862 -1.32796668016224 3 1 0.000595238095238095 1680 17224 55450 CAMK2N1 GO:0004142 diacylglycerol cholinephosphotransferase activity 0.26501557525862 -1.32796668016224 3 1 0.000595238095238095 1680 17224 1040 CDS1 GO:0004705 JUN kinase activity 0.26501557525862 -1.32796668016224 3 1 0.000595238095238095 1680 17224 5602 MAPK10 GO:0003876 AMP deaminase activity 0.26501557525862 -1.32796668016224 3 1 0.000595238095238095 1680 17224 270 AMPD1 GO:0033613 activating transcription factor binding 0.266729864770104 -1.32151887517281 72 9 0.00535714285714286 1680 17224 4088,9658,8320,4609,7466,100271849,4869,10413,4208 SMAD3,ZNF516,EOMES,MYC,WFS1,MEF2B,NPM1,YAP1,MEF2C GO:0008066 glutamate receptor activity 0.266791593019769 -1.32128747585779 27 4 0.00238095238095238 1680 17224 2906,2900,2898,2894 GRIN2D,GRIK4,GRIK2,GRID1 GO:0043236 laminin binding 0.266791593019769 -1.32128747585779 27 4 0.00238095238095238 1680 17224 3958,57211,9353,3673 LGALS3,ADGRG6,SLIT2,ITGA2 GO:0072509 divalent inorganic cation transmembrane transporter activity 0.266791593019769 -1.32128747585779 27 4 0.00238095238095238 1680 17224 23516,30061,7782,64116 SLC39A14,SLC40A1,SLC30A4,SLC39A8 GO:0045505 dynein intermediate chain binding 0.266791593019769 -1.32128747585779 27 4 0.00238095238095238 1680 17224 79659,144132,1767,1768 DYNC2H1,DNHD1,DNAH5,DNAH6 GO:0019894 kinesin binding 0.271531801735143 -1.30367601300496 36 5 0.00297619047619048 1680 17224 23095,3798,57698,55638,6622 KIF1B,KIF5A,SHTN1,SYBU,SNCA GO:0016903 oxidoreductase activity, acting on the aldehyde or oxo group of donors 0.272527405275022 -1.30001610011905 45 6 0.00357142857142857 1680 17224 2597,217,55711,160428,10840,55753 GAPDH,ALDH2,FAR2,ALDH1L2,ALDH1L1,OGDHL GO:0043492 ATPase activity, coupled to movement of substances 0.275042759067572 -1.29082870588405 129 15 0.00892857142857143 1680 17224 10257,23461,10079,540,10396,90423,1244,23250,481,57205,92270,493,490,478,9619 ABCC4,ABCA5,ATP9A,ATP7B,ATP8A1,ATP6V1E2,ABCC2,ATP11A,ATP1B1,ATP10D,ATP6AP1L,ATP2B4,ATP2B1,ATP1A3,ABCG1 GO:0020037 heme binding 0.275042759067572 -1.29082870588405 129 15 0.00892857142857143 1680 17224 1595,3048,55640,6999,1573,50865,8614,285440,875,3046,113612,2977,1592,4846,1545 CYP51A1,HBG2,FLVCR2,TDO2,CYP2J2,HEBP1,STC2,CYP4V2,CBS,HBE1,CYP2U1,GUCY1A2,CYP26A1,NOS3,CYP1B1 GO:0098641 cadherin binding involved in cell-cell adhesion 0.281295944383397 -1.26834798099731 19 3 0.00178571428571429 1680 17224 4072,29091,10458 EPCAM,STXBP6,BAIAP2 GO:0030296 protein tyrosine kinase activator activity 0.281295944383397 -1.26834798099731 19 3 0.00178571428571429 1680 17224 84632,10718,2621 AFAP1L2,NRG3,GAS6 GO:0017127 cholesterol transporter activity 0.281295944383397 -1.26834798099731 19 3 0.00178571428571429 1680 17224 10577,134429,9619 NPC2,STARD4,ABCG1 GO:0051861 glycolipid binding 0.281295944383397 -1.26834798099731 19 3 0.00178571428571429 1680 17224 6402,84725,3306 SELL,PLEKHA8,HSPA2 GO:0015269 calcium-activated potassium channel activity 0.281295944383397 -1.26834798099731 19 3 0.00178571428571429 1680 17224 27345,3781,27094 KCNMB4,KCNN2,KCNMB3 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity 0.281295944383397 -1.26834798099731 19 3 0.00178571428571429 1680 17224 129642,54947,56895 MBOAT2,LPCAT2,AGPAT4 GO:0004890 GABA-A receptor activity 0.281295944383397 -1.26834798099731 19 3 0.00178571428571429 1680 17224 2566,2570,2561 GABRG2,GABRR2,GABRB2 GO:0046982 protein heterodimerization activity 0.283601901709105 -1.26018377874331 481 51 0.0303571428571429 1680 17224 7301,10178,23051,122953,119,4869,5596,1147,5028,22807,7164,654,93986,10388,79955,3078,57186,664,7099,58494,9312,11043,25801,468,8322,3164,665,10413,9935,3092,467,6875,10333,202559,83700,4088,1051,22806,143098,26508,3673,7494,153,54937,3082,7168,4281,1649,9619,58528,4208 TYRO3,TENM1,ZHX3,JDP2,ADD2,NPM1,MAPK4,CHUK,P2RY1,IKZF2,TPD52L1,BMP6,FOXP2,SYCP2,PDZD7,CFHR1,RALGAPA2,BNIP3,TLR4,JAM2,KCNB2,MID2,GCA,ATF4,FZD4,NR4A1,BNIP3L,YAP1,MAFB,HIP1,ATF3,TAF4B,TLR6,KHDRBS2,JAM3,SMAD3,CEBPB,IKZF3,MPP7,HEYL,ITGA2,XBP1,ADRB1,SOHLH2,HGF,TPM1,MID1,DDIT3,ABCG1,RRAGD,MEF2C GO:0008238 exopeptidase activity 0.285309643222537 -1.2541802210446 111 13 0.00773809523809524 1680 17224 57628,4324,10279,54504,5547,23621,1515,119587,9805,1363,4325,254042,4311 DPP10,MMP15,PRSS16,CPVL,PRCP,BACE1,CTSV,CPXM2,SCRN1,CPE,MMP16,METAP1D,MME GO:0005178 integrin binding 0.285309643222537 -1.2541802210446 111 13 0.00773809523809524 1680 17224 2335,1285,2200,8838,7060,3655,3690,3673,1015,5578,6850,83700,84978 FN1,COL4A3,FBN1,WISP3,THBS4,ITGA6,ITGB3,ITGA2,CDH17,PRKCA,SYK,JAM3,FRMD5 GO:0005507 copper ion binding 0.287315188905898 -1.24717544663974 55 7 0.00416666666666667 1680 17224 84171,144811,26002,540,475,6622,5066 LOXL4,LACC1,MOXD1,ATP7B,ATOX1,SNCA,PAM GO:0019209 kinase activator activity 0.288911859023381 -1.24163362346568 83 10 0.00595238095238095 1680 17224 92597,10718,51704,2258,3071,142679,7481,84632,2621,10253 MOB1B,NRG3,GPRC5B,FGF13,NCKAP1L,DUSP19,WNT11,AFAP1L2,GAS6,SPRY2 GO:0005164 tumor necrosis factor receptor binding 0.289354040699174 -1.24010428631408 28 4 0.00238095238095238 1680 17224 9966,7292,1896,10673 TNFSF15,TNFSF4,EDA,TNFSF13B GO:0045309 protein phosphorylated amino acid binding 0.289890001866609 -1.23825373186379 46 6 0.00357142857142857 1680 17224 2268,6452,6850,5777,8945,4734 FGR,SH3BP2,SYK,PTPN6,BTRC,NEDD4 GO:0016409 palmitoyltransferase activity 0.291034694206359 -1.23431279484043 37 5 0.00297619047619048 1680 17224 79683,9227,64429,158866,254887 ZDHHC14,LRAT,ZDHHC6,ZDHHC15,ZDHHC23 GO:0070410 co-SMAD binding 0.292150490586021 -1.2304862307566 11 2 0.00119047619047619 1680 17224 4088,4091 SMAD3,SMAD6 GO:0005165 neurotrophin receptor binding 0.292150490586021 -1.2304862307566 11 2 0.00119047619047619 1680 17224 627,27018 BDNF,BEX3 GO:0017154 semaphorin receptor activity 0.292150490586021 -1.2304862307566 11 2 0.00119047619047619 1680 17224 8829,5362 NRP1,PLXNA2 GO:0045294 alpha-catenin binding 0.292150490586021 -1.2304862307566 11 2 0.00119047619047619 1680 17224 5318,1000 PKP2,CDH2 GO:0008349 MAP kinase kinase kinase kinase activity 0.292150490586021 -1.2304862307566 11 2 0.00119047619047619 1680 17224 23043,8428 TNIK,STK24 GO:0000774 adenyl-nucleotide exchange factor activity 0.292150490586021 -1.2304862307566 11 2 0.00119047619047619 1680 17224 9531,134266 BAG3,GRPEL2 GO:0046030 inositol trisphosphate phosphatase activity 0.292150490586021 -1.2304862307566 11 2 0.00119047619047619 1680 17224 3628,8821 INPP1,INPP4B GO:0015386 potassium:proton antiporter activity 0.292150490586021 -1.2304862307566 11 2 0.00119047619047619 1680 17224 285335,84679 SLC9C1,SLC9A7 GO:0005536 glucose binding 0.292150490586021 -1.2304862307566 11 2 0.00119047619047619 1680 17224 3098,3099 HK1,HK2 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding 0.292150490586021 -1.2304862307566 11 2 0.00119047619047619 1680 17224 9242,60468 MSC,BACH2 GO:0008097 5S rRNA binding 0.292150490586021 -1.2304862307566 11 2 0.00119047619047619 1680 17224 1938,29997 EEF2,NOP53 GO:0045295 gamma-catenin binding 0.292150490586021 -1.2304862307566 11 2 0.00119047619047619 1680 17224 5795,1000 PTPRJ,CDH2 GO:0004896 cytokine receptor activity 0.296173996275126 -1.21680817210586 93 11 0.00654761904761905 1680 17224 643,54756,2690,3597,3581,3977,3556,3953,2674,8809,2152 CXCR5,IL17RD,GHR,IL13RA1,IL9R,LIFR,IL1RAP,LEPR,GFRA1,IL18R1,F3 GO:0001158 enhancer sequence-specific DNA binding 0.296173996275126 -1.21680817210586 93 11 0.00654761904761905 1680 17224 9242,55893,60468,2624,5966,7494,619279,4779,2625,3239,4208 MSC,ZNF395,BACH2,GATA2,REL,XBP1,ZNF704,NFE2L1,GATA3,HOXD13,MEF2C GO:0005249 voltage-gated potassium channel activity 0.296173996275126 -1.21680817210586 93 11 0.00654761904761905 1680 17224 27012,219527,3761,7881,3786,27133,3755,3790,3752,3749,9312 KCNV1,LRRC55,KCNJ4,KCNAB1,KCNQ3,KCNH5,KCNG1,KCNS3,KCND3,KCNC4,KCNB2 GO:0004857 enzyme inhibitor activity 0.299406312144118 -1.20595372457316 395 42 0.025 1680 17224 116154,27344,8434,720,5611,3843,402,4869,2621,11005,6497,9858,10129,23767,4040,5627,871,9353,10253,83666,91272,10188,93974,2597,1447,1285,51232,120892,5577,9749,10399,7453,6622,55450,57761,142679,5274,50859,54997,5569,2810,493 PHACTR3,PCSK1N,RECK,C4A,DNAJC3,IPO5,ARL2,NPM1,GAS6,SPINK5,SKI,PPP1R26,FRY,FLRT3,LRP6,PROS1,SERPINH1,SLIT2,SPRY2,PARP9,BOD1,TNK2,ATP5IF1,GAPDH,CSN2,COL4A3,CRIM1,LRRK2,PRKAR2B,PHACTR2,RACK1,WARS,SNCA,CAMK2N1,TRIB3,DUSP19,SERPINI1,SPOCK3,TESC,PKIA,SFN,ATP2B4 GO:0015293 symporter activity 0.29942469788418 -1.2058923191357 141 16 0.00952380952380952 1680 17224 6536,206358,120103,114134,6507,9990,84879,5002,6567,84068,11182,154091,55117,220963,6510,85414 SLC6A9,SLC36A1,SLC36A4,SLC2A13,SLC1A3,SLC12A6,MFSD2A,SLC22A18,SLC16A2,SLC10A7,SLC2A6,SLC2A12,SLC6A15,SLC16A9,SLC1A5,SLC45A3 GO:0016763 transferase activity, transferring pentosyl groups 0.303274901776414 -1.19311561820151 56 7 0.00416666666666667 1680 17224 727936,1890,56952,4860,64131,83666,23475 GXYLT2,TYMP,PRTFDC1,PNP,XYLT1,PARP9,QPRT GO:0005544 calcium-dependent phospholipid binding 0.303274901776414 -1.19311561820151 56 7 0.00416666666666667 1680 17224 5321,8448,255928,27445,123036,91683,55784 PLA2G4A,DOC2A,SYT14,PCLO,TC2N,SYT12,MCTP2 GO:0005230 extracellular ligand-gated ion channel activity 0.307609122383925 -1.17892538514565 75 9 0.00535714285714286 1680 17224 2566,8973,2906,2900,2570,1138,2898,2561,2894 GABRG2,CHRNA6,GRIN2D,GRIK4,GABRR2,CHRNA5,GRIK2,GABRB2,GRID1 GO:0019887 protein kinase regulator activity 0.307941451990456 -1.17784560501821 200 22 0.0130952380952381 1680 17224 2258,5611,4869,5577,7481,2621,10399,55450,57761,3627,10718,51704,3071,154043,23767,142679,84632,26034,54997,10253,5569,2810 FGF13,DNAJC3,NPM1,PRKAR2B,WNT11,GAS6,RACK1,CAMK2N1,TRIB3,CXCL10,NRG3,GPRC5B,NCKAP1L,CNKSR3,FLRT3,DUSP19,AFAP1L2,IPCEF1,TESC,SPRY2,PKIA,SFN GO:0071617 lysophospholipid acyltransferase activity 0.309030838883333 -1.17431420485287 20 3 0.00178571428571429 1680 17224 129642,54947,56895 MBOAT2,LPCAT2,AGPAT4 GO:0042171 lysophosphatidic acid acyltransferase activity 0.309030838883333 -1.17431420485287 20 3 0.00178571428571429 1680 17224 129642,54947,56895 MBOAT2,LPCAT2,AGPAT4 GO:0015144 carbohydrate transmembrane transporter activity 0.310770484880565 -1.16870062998985 38 5 0.00297619047619048 1680 17224 154091,148808,114134,85414,11182 SLC2A12,MFSD4A,SLC2A13,SLC45A3,SLC2A6 GO:0019212 phosphatase inhibitor activity 0.310770484880565 -1.16870062998985 38 5 0.00297619047619048 1680 17224 116154,9749,9858,54997,91272 PHACTR3,PHACTR2,PPP1R26,TESC,BOD1 GO:0051959 dynein light intermediate chain binding 0.312161059253753 -1.16423600880917 29 4 0.00238095238095238 1680 17224 79659,144132,1767,1768 DYNC2H1,DNHD1,DNAH5,DNAH6 GO:0005504 fatty acid binding 0.312161059253753 -1.16423600880917 29 4 0.00238095238095238 1680 17224 10247,3399,241,6622 RIDA,ID3,ALOX5AP,SNCA GO:0016853 isomerase activity 0.312752027827703 -1.16234464579458 152 17 0.0101190476190476 1680 17224 5768,1962,84650,51477,51303,26035,81567,11328,5903,3157,3422,56605,3690,283209,92126,55033,9536 QSOX1,EHHADH,EBPL,ISYNA1,FKBP11,GLCE,TXNDC5,FKBP9,RANBP2,HMGCS1,IDI1,ERO1B,ITGB3,PGM2L1,DSEL,FKBP14,PTGES GO:0019829 cation-transporting ATPase activity 0.313491101867772 -1.15998430250887 66 8 0.00476190476190476 1680 17224 90423,481,540,92270,10396,493,490,478 ATP6V1E2,ATP1B1,ATP7B,ATP6AP1L,ATP8A1,ATP2B4,ATP2B1,ATP1A3 GO:0015081 sodium ion transmembrane transporter activity 0.315734799596223 -1.15285265953987 162 18 0.0107142857142857 1680 17224 54795,6331,6520,6536,2898,285335,6334,481,6507,84679,2900,6324,41,55117,6326,150159,6328,478 TRPM4,SCN5A,SLC3A2,SLC6A9,GRIK2,SLC9C1,SCN8A,ATP1B1,SLC1A3,SLC9A7,GRIK4,SCN1B,ASIC1,SLC6A15,SCN2A,SLC9B1,SCN3A,ATP1A3 GO:0022824 transmitter-gated ion channel activity 0.319407895794096 -1.1412863227989 57 7 0.00416666666666667 1680 17224 2566,8973,2906,2900,1138,2898,2894 GABRG2,CHRNA6,GRIN2D,GRIK4,CHRNA5,GRIK2,GRID1 GO:0022835 transmitter-gated channel activity 0.319407895794096 -1.1412863227989 57 7 0.00416666666666667 1680 17224 2566,8973,2906,2900,1138,2898,2894 GABRG2,CHRNA6,GRIN2D,GRIK4,CHRNA5,GRIK2,GRID1 GO:0030295 protein kinase activator activity 0.321548032068653 -1.13460834656102 76 9 0.00535714285714286 1680 17224 10718,51704,2258,3071,142679,7481,84632,2621,10253 NRG3,GPRC5B,FGF13,NCKAP1L,DUSP19,WNT11,AFAP1L2,GAS6,SPRY2 GO:0005231 excitatory extracellular ligand-gated ion channel activity 0.325228954204211 -1.12322587020357 48 6 0.00357142857142857 1680 17224 8973,2906,2900,1138,2898,2894 CHRNA6,GRIN2D,GRIK4,CHRNA5,GRIK2,GRID1 GO:0043274 phospholipase binding 0.329663276826115 -1.10968351871099 12 2 0.00119047619047619 1680 17224 5071,6812 PRKN,STXBP1 GO:0008020 G-protein coupled photoreceptor activity 0.329663276826115 -1.10968351871099 12 2 0.00119047619047619 1680 17224 6785,23596 ELOVL4,OPN3 GO:0070700 BMP receptor binding 0.329663276826115 -1.10968351871099 12 2 0.00119047619047619 1680 17224 652,654 BMP4,BMP6 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives 0.329663276826115 -1.10968351871099 12 2 0.00119047619047619 1680 17224 92126,26035 DSEL,GLCE GO:1901611 phosphatidylglycerol binding 0.329663276826115 -1.10968351871099 12 2 0.00119047619047619 1680 17224 5360,1687 PLTP,GSDME GO:0036041 long-chain fatty acid binding 0.329663276826115 -1.10968351871099 12 2 0.00119047619047619 1680 17224 10247,241 RIDA,ALOX5AP GO:0042043 neurexin family protein binding 0.329663276826115 -1.10968351871099 12 2 0.00119047619047619 1680 17224 57502,1363 NLGN4X,CPE GO:0015174 basic amino acid transmembrane transporter activity 0.329663276826115 -1.10968351871099 12 2 0.00119047619047619 1680 17224 6541,6542 SLC7A1,SLC7A2 GO:0043225 ATPase-coupled anion transmembrane transporter activity 0.329663276826115 -1.10968351871099 12 2 0.00119047619047619 1680 17224 1244,10257 ABCC2,ABCC4 GO:0005391 sodium:potassium-exchanging ATPase activity 0.329663276826115 -1.10968351871099 12 2 0.00119047619047619 1680 17224 481,478 ATP1B1,ATP1A3 GO:0008556 potassium-transporting ATPase activity 0.329663276826115 -1.10968351871099 12 2 0.00119047619047619 1680 17224 481,478 ATP1B1,ATP1A3 GO:0047372 acylglycerol lipase activity 0.329663276826115 -1.10968351871099 12 2 0.00119047619047619 1680 17224 747,57406 DAGLA,ABHD6 GO:0005225 volume-sensitive anion channel activity 0.329663276826115 -1.10968351871099 12 2 0.00119047619047619 1680 17224 94015,23507 TTYH2,LRRC8B GO:0015248 sterol transporter activity 0.33512015177423 -1.09326614944829 30 4 0.00238095238095238 1680 17224 10577,114880,134429,9619 NPC2,OSBPL6,STARD4,ABCG1 GO:0015491 cation:cation antiporter activity 0.33512015177423 -1.09326614944829 30 4 0.00238095238095238 1680 17224 6520,285335,150159,84679 SLC3A2,SLC9C1,SLC9B1,SLC9A7 GO:0052866 phosphatidylinositol phosphate phosphatase activity 0.33512015177423 -1.09326614944829 30 4 0.00238095238095238 1680 17224 22876,3636,9896,8821 INPP5F,INPPL1,FIG4,INPP4B GO:0019888 protein phosphatase regulator activity 0.335608727190837 -1.09180929998693 77 9 0.00535714285714286 1680 17224 116154,9858,57718,9749,5521,11123,5523,91272,3486 PHACTR3,PPP1R26,PPP4R4,PHACTR2,PPP2R2B,RCAN3,PPP2R3A,BOD1,IGFBP3 GO:0005030 neurotrophin receptor activity 0.336717208938382 -1.08851184352311 4 1 0.000595238095238095 1680 17224 4916 NTRK3 GO:0008486 diphosphoinositol-polyphosphate diphosphatase activity 0.336717208938382 -1.08851184352311 4 1 0.000595238095238095 1680 17224 170685 NUDT10 GO:0035650 AP-1 adaptor complex binding 0.336717208938382 -1.08851184352311 4 1 0.000595238095238095 1680 17224 23682 RAB38 GO:0102121 ceramidase activity 0.336717208938382 -1.08851184352311 4 1 0.000595238095238095 1680 17224 340485 ACER2 GO:0048763 calcium-induced calcium release activity 0.336717208938382 -1.08851184352311 4 1 0.000595238095238095 1680 17224 6262 RYR2 GO:0004583 dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity 0.336717208938382 -1.08851184352311 4 1 0.000595238095238095 1680 17224 144245 ALG10B GO:0008401 retinoic acid 4-hydroxylase activity 0.336717208938382 -1.08851184352311 4 1 0.000595238095238095 1680 17224 1592 CYP26A1 GO:0052845 inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity 0.336717208938382 -1.08851184352311 4 1 0.000595238095238095 1680 17224 170685 NUDT10 GO:0035662 Toll-like receptor 4 binding 0.336717208938382 -1.08851184352311 4 1 0.000595238095238095 1680 17224 153090 DAB2IP GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity 0.336717208938382 -1.08851184352311 4 1 0.000595238095238095 1680 17224 5163 PDK1 GO:0052846 inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity 0.336717208938382 -1.08851184352311 4 1 0.000595238095238095 1680 17224 170685 NUDT10 GO:0004897 ciliary neurotrophic factor receptor activity 0.336717208938382 -1.08851184352311 4 1 0.000595238095238095 1680 17224 3977 LIFR GO:0052832 inositol monophosphate 3-phosphatase activity 0.336717208938382 -1.08851184352311 4 1 0.000595238095238095 1680 17224 22876 INPP5F GO:0004427 inorganic diphosphatase activity 0.336717208938382 -1.08851184352311 4 1 0.000595238095238095 1680 17224 64077 LHPP GO:0005025 transforming growth factor beta receptor activity, type I 0.336717208938382 -1.08851184352311 4 1 0.000595238095238095 1680 17224 90 ACVR1 GO:0034648 histone demethylase activity (H3-dimethyl-K4 specific) 0.336717208938382 -1.08851184352311 4 1 0.000595238095238095 1680 17224 10765 KDM5B GO:0102344 3-hydroxy-behenoyl-CoA dehydratase activity 0.336717208938382 -1.08851184352311 4 1 0.000595238095238095 1680 17224 9200 HACD1 GO:0008934 inositol monophosphate 1-phosphatase activity 0.336717208938382 -1.08851184352311 4 1 0.000595238095238095 1680 17224 22876 INPP5F GO:0050220 prostaglandin-E synthase activity 0.336717208938382 -1.08851184352311 4 1 0.000595238095238095 1680 17224 9536 PTGES GO:0052833 inositol monophosphate 4-phosphatase activity 0.336717208938382 -1.08851184352311 4 1 0.000595238095238095 1680 17224 22876 INPP5F GO:0010858 calcium-dependent protein kinase regulator activity 0.336717208938382 -1.08851184352311 4 1 0.000595238095238095 1680 17224 55450 CAMK2N1 GO:0052844 inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity 0.336717208938382 -1.08851184352311 4 1 0.000595238095238095 1680 17224 170685 NUDT10 GO:0015119 hexose phosphate transmembrane transporter activity 0.336717208938382 -1.08851184352311 4 1 0.000595238095238095 1680 17224 54020 SLC37A1 GO:0034431 bis(5'-adenosyl)-hexaphosphatase activity 0.336717208938382 -1.08851184352311 4 1 0.000595238095238095 1680 17224 170685 NUDT10 GO:0102345 3-hydroxy-lignoceroyl-CoA dehydratase activity 0.336717208938382 -1.08851184352311 4 1 0.000595238095238095 1680 17224 9200 HACD1 GO:0044736 acid-sensing ion channel activity 0.336717208938382 -1.08851184352311 4 1 0.000595238095238095 1680 17224 41 ASIC1 GO:0004376 glycolipid mannosyltransferase activity 0.336717208938382 -1.08851184352311 4 1 0.000595238095238095 1680 17224 440138 ALG11 GO:0052843 inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity 0.336717208938382 -1.08851184352311 4 1 0.000595238095238095 1680 17224 170685 NUDT10 GO:0042296 ISG15 transferase activity 0.336717208938382 -1.08851184352311 4 1 0.000595238095238095 1680 17224 51191 HERC5 GO:0106017 phosphatidylinositol-3,4-bisphosphate phosphatase activity 0.336717208938382 -1.08851184352311 4 1 0.000595238095238095 1680 17224 8821 INPP4B GO:0030151 molybdenum ion binding 0.336717208938382 -1.08851184352311 4 1 0.000595238095238095 1680 17224 55034 MOCOS GO:0097644 calcitonin family binding 0.336717208938382 -1.08851184352311 4 1 0.000595238095238095 1680 17224 10203 CALCRL GO:0016167 glial cell-derived neurotrophic factor receptor activity 0.336717208938382 -1.08851184352311 4 1 0.000595238095238095 1680 17224 2674 GFRA1 GO:0008330 protein tyrosine/threonine phosphatase activity 0.336717208938382 -1.08851184352311 4 1 0.000595238095238095 1680 17224 1843 DUSP1 GO:0034432 bis(5'-adenosyl)-pentaphosphatase activity 0.336717208938382 -1.08851184352311 4 1 0.000595238095238095 1680 17224 170685 NUDT10 GO:0016453 C-acetyltransferase activity 0.336717208938382 -1.08851184352311 4 1 0.000595238095238095 1680 17224 23464 GCAT GO:0019828 aspartic-type endopeptidase inhibitor activity 0.336717208938382 -1.08851184352311 4 1 0.000595238095238095 1680 17224 2597 GAPDH GO:0070815 peptidyl-lysine 5-dioxygenase activity 0.336717208938382 -1.08851184352311 4 1 0.000595238095238095 1680 17224 5352 PLOD2 GO:0097016 L27 domain binding 0.336717208938382 -1.08851184352311 4 1 0.000595238095238095 1680 17224 8825 LIN7A GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity 0.336717208938382 -1.08851184352311 4 1 0.000595238095238095 1680 17224 55753 OGDHL GO:0090722 receptor-receptor interaction 0.336717208938382 -1.08851184352311 4 1 0.000595238095238095 1680 17224 2260 FGFR1 GO:0034485 phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity 0.336717208938382 -1.08851184352311 4 1 0.000595238095238095 1680 17224 3636 INPPL1 GO:0005087 Ran guanyl-nucleotide exchange factor activity 0.336717208938382 -1.08851184352311 4 1 0.000595238095238095 1680 17224 26297 SERGEF GO:0005105 type 1 fibroblast growth factor receptor binding 0.336717208938382 -1.08851184352311 4 1 0.000595238095238095 1680 17224 8822 FGF17 GO:0005250 A-type (transient outward) potassium channel activity 0.336717208938382 -1.08851184352311 4 1 0.000595238095238095 1680 17224 3752 KCND3 GO:0033265 choline binding 0.336717208938382 -1.08851184352311 4 1 0.000595238095238095 1680 17224 590 BCHE GO:0018812 3-hydroxyacyl-CoA dehydratase activity 0.336717208938382 -1.08851184352311 4 1 0.000595238095238095 1680 17224 9200 HACD1 GO:0015526 hexose-phosphate:inorganic phosphate antiporter activity 0.336717208938382 -1.08851184352311 4 1 0.000595238095238095 1680 17224 54020 SLC37A1 GO:0008410 CoA-transferase activity 0.336717208938382 -1.08851184352311 4 1 0.000595238095238095 1680 17224 79783 SUGCT GO:0030292 protein tyrosine kinase inhibitor activity 0.336717208938382 -1.08851184352311 4 1 0.000595238095238095 1680 17224 10399 RACK1 GO:0033743 peptide-methionine (R)-S-oxide reductase activity 0.336717208938382 -1.08851184352311 4 1 0.000595238095238095 1680 17224 253827 MSRB3 GO:0052842 inositol diphosphate pentakisphosphate diphosphatase activity 0.336717208938382 -1.08851184352311 4 1 0.000595238095238095 1680 17224 170685 NUDT10 GO:0005219 ryanodine-sensitive calcium-release channel activity 0.336717208938382 -1.08851184352311 4 1 0.000595238095238095 1680 17224 6262 RYR2 GO:0102158 very-long-chain 3-hydroxyacyl-CoA dehydratase activity 0.336717208938382 -1.08851184352311 4 1 0.000595238095238095 1680 17224 9200 HACD1 GO:0002054 nucleobase binding 0.336717208938382 -1.08851184352311 4 1 0.000595238095238095 1680 17224 4860 PNP GO:0099104 potassium channel activator activity 0.336717208938382 -1.08851184352311 4 1 0.000595238095238095 1680 17224 219527 LRRC55 GO:0016972 thiol oxidase activity 0.336717208938382 -1.08851184352311 4 1 0.000595238095238095 1680 17224 5768 QSOX1 GO:0052847 inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity 0.336717208938382 -1.08851184352311 4 1 0.000595238095238095 1680 17224 170685 NUDT10 GO:0000298 endopolyphosphatase activity 0.336717208938382 -1.08851184352311 4 1 0.000595238095238095 1680 17224 170685 NUDT10 GO:0034597 phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity 0.336717208938382 -1.08851184352311 4 1 0.000595238095238095 1680 17224 8821 INPP4B GO:0004687 myosin light chain kinase activity 0.336717208938382 -1.08851184352311 4 1 0.000595238095238095 1680 17224 91807 MYLK3 GO:0036137 kynurenine aminotransferase activity 0.336717208938382 -1.08851184352311 4 1 0.000595238095238095 1680 17224 51166 AADAT GO:0016286 small conductance calcium-activated potassium channel activity 0.336717208938382 -1.08851184352311 4 1 0.000595238095238095 1680 17224 3781 KCNN2 GO:0052840 inositol diphosphate tetrakisphosphate diphosphatase activity 0.336717208938382 -1.08851184352311 4 1 0.000595238095238095 1680 17224 170685 NUDT10 GO:0004706 JUN kinase kinase kinase activity 0.336717208938382 -1.08851184352311 4 1 0.000595238095238095 1680 17224 84451 MAP3K21 GO:0034617 tetrahydrobiopterin binding 0.336717208938382 -1.08851184352311 4 1 0.000595238095238095 1680 17224 4846 NOS3 GO:0052834 inositol monophosphate phosphatase activity 0.336717208938382 -1.08851184352311 4 1 0.000595238095238095 1680 17224 22876 INPP5F GO:0052848 inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity 0.336717208938382 -1.08851184352311 4 1 0.000595238095238095 1680 17224 170685 NUDT10 GO:0043532 angiostatin binding 0.336717208938382 -1.08851184352311 4 1 0.000595238095238095 1680 17224 93974 ATP5IF1 GO:0032396 inhibitory MHC class I receptor activity 0.336717208938382 -1.08851184352311 4 1 0.000595238095238095 1680 17224 10859 LILRB1 GO:0032422 purine-rich negative regulatory element binding 0.336717208938382 -1.08851184352311 4 1 0.000595238095238095 1680 17224 29942 PURG GO:0052841 inositol bisdiphosphate tetrakisphosphate diphosphatase activity 0.336717208938382 -1.08851184352311 4 1 0.000595238095238095 1680 17224 170685 NUDT10 GO:0004515 nicotinate-nucleotide adenylyltransferase activity 0.336717208938382 -1.08851184352311 4 1 0.000595238095238095 1680 17224 349565 NMNAT3 GO:0102343 3-hydroxy-arachidoyl-CoA dehydratase activity 0.336717208938382 -1.08851184352311 4 1 0.000595238095238095 1680 17224 9200 HACD1 GO:0004127 cytidylate kinase activity 0.336717208938382 -1.08851184352311 4 1 0.000595238095238095 1680 17224 129607 CMPK2 GO:0061513 glucose 6-phosphate:inorganic phosphate antiporter activity 0.336717208938382 -1.08851184352311 4 1 0.000595238095238095 1680 17224 54020 SLC37A1 GO:0016212 kynurenine-oxoglutarate transaminase activity 0.336717208938382 -1.08851184352311 4 1 0.000595238095238095 1680 17224 51166 AADAT GO:0045569 TRAIL binding 0.336717208938382 -1.08851184352311 4 1 0.000595238095238095 1680 17224 8794 TNFRSF10C GO:0099103 channel activator activity 0.336717208938382 -1.08851184352311 4 1 0.000595238095238095 1680 17224 219527 LRRC55 GO:0072320 volume-sensitive chloride channel activity 0.336717208938382 -1.08851184352311 4 1 0.000595238095238095 1680 17224 94015 TTYH2 GO:0015315 organophosphate:inorganic phosphate antiporter activity 0.336717208938382 -1.08851184352311 4 1 0.000595238095238095 1680 17224 54020 SLC37A1 GO:0016807 cysteine-type carboxypeptidase activity 0.336717208938382 -1.08851184352311 4 1 0.000595238095238095 1680 17224 1515 CTSV GO:0070004 cysteine-type exopeptidase activity 0.336717208938382 -1.08851184352311 4 1 0.000595238095238095 1680 17224 1515 CTSV GO:0008373 sialyltransferase activity 0.336843473341486 -1.08813692732653 21 3 0.00178571428571429 1680 17224 256435,6489,6480 ST6GALNAC3,ST8SIA1,ST6GAL1 GO:0004602 glutathione peroxidase activity 0.336843473341486 -1.08813692732653 21 3 0.00178571428571429 1680 17224 2946,241,4259 GSTM2,ALOX5AP,MGST3 GO:0015645 fatty acid ligase activity 0.336843473341486 -1.08813692732653 21 3 0.00178571428571429 1680 17224 2180,11001,6296 ACSL1,SLC27A2,ACSM3 GO:0051721 protein phosphatase 2A binding 0.336843473341486 -1.08813692732653 21 3 0.00178571428571429 1680 17224 153090,55917,91272 DAB2IP,CTTNBP2NL,BOD1 GO:0016684 oxidoreductase activity, acting on peroxide as acceptor 0.343119158212913 -1.06967749210797 49 6 0.00357142857142857 1680 17224 83667,2946,26034,241,27244,4259 SESN2,GSTM2,IPCEF1,ALOX5AP,SESN1,MGST3 GO:0000149 SNARE binding 0.344932808859405 -1.06440563784763 126 14 0.00833333333333333 1680 17224 8448,9515,10497,9871,91683,120892,8673,55638,54732,6616,255928,6812,123036,9751 DOC2A,STXBP5L,UNC13B,SEC24D,SYT12,LRRK2,VAMP8,SYBU,TMED9,SNAP25,SYT14,STXBP1,TC2N,SNPH GO:0000988 transcription factor activity, protein binding 0.354104243588908 -1.03816393578215 404 42 0.025 1680 17224 29842,3397,4601,23051,23543,29995,6756,4869,1488,6497,8320,2963,9443,8531,116931,83666,30818,468,4212,10765,4779,10413,467,23414,256536,55509,473,57491,4088,57761,9242,64324,3399,11278,138151,26508,25937,51460,10891,284252,1649,23462 TFCP2L1,ID1,MXI1,ZHX3,RBFOX2,LMCD1,SSX1,NPM1,CTBP2,SKI,EOMES,GTF2F2,MED7,YBX3,MED12L,PARP9,KCNIP3,ATF4,MEIS2,KDM5B,NFE2L1,YAP1,ATF3,ZFPM2,TCERG1L,BATF3,RERE,AHRR,SMAD3,TRIB3,MSC,NSD1,ID3,KLF12,NACC2,HEYL,WWTR1,SFMBT1,PPARGC1A,KCTD1,DDIT3,HEY1 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed 0.358143635302205 -1.02682115711908 31 4 0.00238095238095238 1680 17224 3800,1780,23095,3798 KIF5C,DYNC1I1,KIF1B,KIF5A GO:0140110 transcription regulator activity 0.359727351043464 -1.0224088926852 2112 211 0.125595238095238 1680 17224 29995,2625,4869,1488,6777,1050,22807,117154,7227,6497,64376,8320,29841,1750,11262,2115,2023,114821,5455,346157,7080,30818,4212,468,4093,2649,4774,147929,4779,10413,100271849,10538,256536,388507,57491,9149,83439,10781,3131,11278,135112,26137,1746,10891,63973,63920,4300,11178,4208,64919,11279,860,55893,23051,219749,122953,9569,26040,7762,7546,6304,2290,2122,158405,253461,6940,2624,126070,4609,85416,6720,57593,23426,9443,85460,148979,56033,1052,25946,23361,30062,6775,84159,100289635,2274,7468,23286,9935,6604,639,6875,148156,5325,26508,51460,3239,26257,10736,64764,29842,5071,3397,9658,23543,282890,5013,55769,255877,64900,221833,79149,149076,220929,5462,26468,604,25925,5452,10794,4661,57670,93349,6591,2735,81550,11166,59336,579,23314,467,474,114991,148266,55509,53335,7552,252884,4088,9242,81931,22806,60468,5579,90874,25937,54937,688,657,1628,3219,4306,29942,55762,284252,23462,4601,5966,5324,6756,56978,9586,58495,5585,51222,84525,4825,93986,10265,168620,2334,2963,7020,8848,687,8531,2672,4091,678,116931,83666,4487,10765,3174,1112,2104,3164,9516,23414,3198,7545,473,283078,1879,1051,643836,57761,64324,3399,138151,91133,7761,7494,7703,388558,745,5083,56906,6474,1649,3169,9310 LMCD1,GATA3,NPM1,CTBP2,STAT5B,CEBPA,IKZF2,DACH2,TRPS1,SKI,IKZF5,EOMES,GRHL1,DLX6,SP140,ETV1,ENO1,ZBED9,POU3F3,ZNF391,NKX2-1,KCNIP3,MEIS2,ATF4,SMAD9,NR6A1,NFIA,ZNF565,NFE2L1,YAP1,MEF2B,BATF,TCERG1L,ZNF788P,AHRR,DYRK1B,TCF7L1,ZNF266,HLF,KLF12,NCOA7,ZBTB20,DLX2,PPARGC1A,NEUROG2,ZBED8,MLLT3,LZTS1,MEF2C,BCL11B,KLF8,RUNX2,ZNF395,ZHX3,ZNF25,JDP2,GTF2IRD1,SETBP1,ZNF215,ZIC2,SATB1,FOXG1,MECOM,KIAA1958,ZBTB38,ZNF354A,GATA2,ZNF440,MYC,ZIC5,SREBF1,EBF4,GRIP1,MED7,ZNF518B,GLIS1,BARX1,CEBPD,ZNF385A,ZNF629,RAX,STAT4,ARID5B,ZNF605,FHL2,NSD2,WWC1,MAFB,SMARCD3,PRDM1,TAF4B,ZNF558,PLAGL1,HEYL,SFMBT1,HOXD13,NKX2-8,SIX2,CREB3L2,TFCP2L1,PRKN,ID1,ZNF516,RBFOX2,ZNF311,OTX1,ZNF83,BCL6B,LPIN3,SP8,ZSCAN5A,ZNF362,ZNF438,POU5F1B,LHX6,BCL6,ZNF521,POU2F2,ZNF460,MYT1,KIAA1549,SP140L,SNAI2,GLI1,TDRD3,SOX21,PRDM13,NKX3-2,SATB2,ATF3,ATOH1,ZNF618,ZNF569,BATF3,BCL11A,ZNF711,ZNF396,SMAD3,MSC,ZNF93,IKZF3,BACH2,PRKCB,ZNF697,WWTR1,SOHLH2,KLF5,BMPR1A,DBP,HOXB9,NR3C2,PURG,ZNF701,KCTD1,HEY1,MXI1,REL,PLAG1,SSX1,PRDM8,CREB5,OVOL2,PKN1,ZNF219,HOPX,NKX6-1,FOXP2,IRX5,BHLHA15,AFF2,GTF2F2,TFAP2A,TSC22D1,KLF9,YBX3,GFI1,SMAD6,ZFP36L2,MED12L,PARP9,MSX1,KDM5B,HNF4G,FOXN3,ESRRG,NR4A1,LITAF,ZFPM2,HOXA1,ZIC1,RERE,MKX,EBF1,CEBPB,ZFP62,TRIB3,NSD1,ID3,NACC2,L3MBTL4,ZNF214,XBP1,PCGF2,ZNF808,MYRF,PAX9,THAP10,SHOX2,DDIT3,FOXA1,ZNF235 GO:0050660 flavin adenine dinucleotide binding 0.364012952145697 -1.0105658291606 79 9 0.00535714285714286 1680 17224 9645,8564,2329,51700,1718,6713,197257,4846,114112 MICAL2,KMO,FMO4,CYB5R2,DHCR24,SQLE,LDHD,NOS3,TXNRD3 GO:0016849 phosphorus-oxygen lyase activity 0.364587098893994 -1.0089898016368 22 3 0.00178571428571429 1680 17224 112,2977,107 ADCY6,GUCY1A2,ADCY1 GO:0016917 GABA receptor activity 0.364587098893994 -1.0089898016368 22 3 0.00178571428571429 1680 17224 2566,2570,2561 GABRG2,GABRR2,GABRB2 GO:0005385 zinc ion transmembrane transporter activity 0.364587098893994 -1.0089898016368 22 3 0.00178571428571429 1680 17224 23516,7782,64116 SLC39A14,SLC30A4,SLC39A8 GO:0015464 acetylcholine receptor activity 0.364587098893994 -1.0089898016368 22 3 0.00178571428571429 1680 17224 8973,1138,1131 CHRNA6,CHRNA5,CHRM3 GO:0070330 aromatase activity 0.364587098893994 -1.0089898016368 22 3 0.00178571428571429 1680 17224 113612,1573,1545 CYP2U1,CYP2J2,CYP1B1 GO:0008093 cytoskeletal adaptor activity 0.366596724191541 -1.00349287926419 13 2 0.00119047619047619 1680 17224 4130,10458 MAP1A,BAIAP2 GO:0005123 death receptor binding 0.366596724191541 -1.00349287926419 13 2 0.00119047619047619 1680 17224 153090,27018 DAB2IP,BEX3 GO:0015037 peptide disulfide oxidoreductase activity 0.366596724191541 -1.00349287926419 13 2 0.00119047619047619 1680 17224 9446,119391 GSTO1,GSTO2 GO:0008179 adenylate cyclase binding 0.366596724191541 -1.00349287926419 13 2 0.00119047619047619 1680 17224 9495,10486 AKAP5,CAP2 GO:0016653 oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor 0.366596724191541 -1.00349287926419 13 2 0.00119047619047619 1680 17224 51700,4846 CYB5R2,NOS3 GO:0035925 mRNA 3'-UTR AU-rich region binding 0.366596724191541 -1.00349287926419 13 2 0.00119047619047619 1680 17224 678,64506 ZFP36L2,CPEB1 GO:0048156 tau protein binding 0.366596724191541 -1.00349287926419 13 2 0.00119047619047619 1680 17224 3306,6622 HSPA2,SNCA GO:0000900 translation repressor activity, mRNA regulatory element binding 0.366596724191541 -1.00349287926419 13 2 0.00119047619047619 1680 17224 400961,64506 PAIP2B,CPEB1 GO:0031435 mitogen-activated protein kinase kinase kinase binding 0.366596724191541 -1.00349287926419 13 2 0.00119047619047619 1680 17224 153090,142679 DAB2IP,DUSP19 GO:0004467 long-chain fatty acid-CoA ligase activity 0.366596724191541 -1.00349287926419 13 2 0.00119047619047619 1680 17224 2180,11001 ACSL1,SLC27A2 GO:0005521 lamin binding 0.366596724191541 -1.00349287926419 13 2 0.00119047619047619 1680 17224 23236,665 PLCB1,BNIP3L GO:0031543 peptidyl-proline dioxygenase activity 0.366596724191541 -1.00349287926419 13 2 0.00119047619047619 1680 17224 5033,8974 P4HA1,P4HA2 GO:0019215 intermediate filament binding 0.366596724191541 -1.00349287926419 13 2 0.00119047619047619 1680 17224 5318,7431 PKP2,VIM GO:0008494 translation activator activity 0.366596724191541 -1.00349287926419 13 2 0.00119047619047619 1680 17224 23367,9811 LARP1,CTIF GO:0140104 molecular carrier activity 0.3707762578776 -0.99215647679672 41 5 0.00297619047619048 1680 17224 3048,3046,26034,3839,475 HBG2,HBE1,IPCEF1,KPNA3,ATOX1 GO:0043178 alcohol binding 0.378315626347679 -0.972026441435275 80 9 0.00535714285714286 1680 17224 8435,134429,114879,7220,3709,10577,7222,9227,9619 SOAT2,STARD4,OSBPL5,TRPC1,ITPR2,NPC2,TRPC3,LRAT,ABCG1 GO:0035258 steroid hormone receptor binding 0.378315626347679 -0.972026441435275 80 9 0.00535714285714286 1680 17224 4088,64324,5579,3164,2274,23426,6777,10891,5585 SMAD3,NSD1,PRKCB,NR4A1,FHL2,GRIP1,STAT5B,PPARGC1A,PKN1 GO:0046906 tetrapyrrole binding 0.380020296928422 -0.967530614718596 139 15 0.00892857142857143 1680 17224 1595,3048,55640,6999,1573,50865,8614,285440,875,3046,113612,2977,1592,4846,1545 CYP51A1,HBG2,FLVCR2,TDO2,CYP2J2,HEBP1,STC2,CYP4V2,CBS,HBE1,CYP2U1,GUCY1A2,CYP26A1,NOS3,CYP1B1 GO:0019208 phosphatase regulator activity 0.381660892729041 -0.963222779997193 90 10 0.00595238095238095 1680 17224 116154,9858,57718,9749,5521,11123,54997,5523,91272,3486 PHACTR3,PPP1R26,PPP4R4,PHACTR2,PPP2R2B,RCAN3,TESC,PPP2R3A,BOD1,IGFBP3 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding 0.384332836264665 -0.956246340709002 100 11 0.00654761904761905 1680 17224 1051,9242,60468,5966,4779,100271849,9569,1050,2735,7080,4208 CEBPB,MSC,BACH2,REL,NFE2L1,MEF2B,GTF2IRD1,CEBPA,GLI1,NKX2-1,MEF2C GO:0016667 oxidoreductase activity, acting on a sulfur group of donors 0.385029651117739 -0.954434931769692 61 7 0.00416666666666667 1680 17224 253827,5768,9446,83667,119391,56605,114112 MSRB3,QSOX1,GSTO1,SESN2,GSTO2,ERO1B,TXNRD3 GO:0016782 transferase activity, transferring sulfur-containing groups 0.389370587470179 -0.943223721844461 71 8 0.00476190476190476 1680 17224 10090,55034,92126,9953,79783,9486,222537,266722 UST,MOCOS,DSEL,HS3ST3B1,SUGCT,CHST10,HS3ST5,HS6ST3 GO:0046332 SMAD binding 0.389370587470179 -0.943223721844461 71 8 0.00476190476190476 1680 17224 4088,657,90,7049,9863,56937,4091,6497 SMAD3,BMPR1A,ACVR1,TGFBR3,MAGI2,PMEPA1,SMAD6,SKI GO:0001085 RNA polymerase II transcription factor binding 0.390876808813618 -0.939362835613642 140 15 0.00892857142857143 1680 17224 4088,3399,3397,468,8320,2624,51339,7494,100271849,2625,23414,256536,4208,473,7227 SMAD3,ID3,ID1,ATF4,EOMES,GATA2,DACT1,XBP1,MEF2B,GATA3,ZFPM2,TCERG1L,MEF2C,RERE,TRPS1 GO:0070412 R-SMAD binding 0.392129929086665 -0.936162042357976 23 3 0.00178571428571429 1680 17224 4088,56937,4091 SMAD3,PMEPA1,SMAD6 GO:0050997 quaternary ammonium group binding 0.392129929086665 -0.936162042357976 23 3 0.00178571428571429 1680 17224 3512,5360,10125 JCHAIN,PLTP,RASGRP1 GO:0031210 phosphatidylcholine binding 0.392129929086665 -0.936162042357976 23 3 0.00178571428571429 1680 17224 3512,5360,10125 JCHAIN,PLTP,RASGRP1 GO:0009975 cyclase activity 0.392129929086665 -0.936162042357976 23 3 0.00178571428571429 1680 17224 112,2977,107 ADCY6,GUCY1A2,ADCY1 GO:0061630 ubiquitin protein ligase activity 0.395116909574372 -0.928573584266558 230 24 0.0142857142857143 1680 17224 91694,5071,153830,9781,26272,57520,51191,54941,11237,55008,22838,4734,143279,285671,154214,57161,10612,9443,64219,79845,143384,8945,220441,57531 LONRF1,PRKN,RNF145,RNF144A,FBXO4,HECW2,HERC5,RNF125,RNF24,HERC6,RNF44,NEDD4,HECTD2,RNF180,RNF217,PELI2,TRIM3,MED7,PJA1,RNF122,CACUL1,BTRC,RNF152,HACE1 GO:0008146 sulfotransferase activity 0.397175316123457 -0.92337749344647 52 6 0.00357142857142857 1680 17224 10090,92126,9953,9486,222537,266722 UST,DSEL,HS3ST3B1,CHST10,HS3ST5,HS6ST3 GO:0045182 translation regulator activity 0.397175316123457 -0.92337749344647 52 6 0.00357142857142857 1680 17224 10644,400961,1978,64506,23367,9811 IGF2BP2,PAIP2B,EIF4EBP1,CPEB1,LARP1,CTIF GO:0016788 hydrolase activity, acting on ester bonds 0.397459794782496 -0.92266149520454 754 76 0.0452380952380952 1680 17224 5321,5153,1850,11099,84945,64900,63874,57406,16,2070,22843,10247,8611,8555,27143,5521,5144,5791,79605,54961,10076,5208,5777,284161,9829,8612,57502,92370,64943,3669,5167,5795,133121,2081,8821,142679,5802,2073,22876,5723,3636,5789,84959,55301,79008,147111,3628,81544,80055,760,200558,590,10846,9896,57552,2098,1131,10924,1843,23491,5210,5509,5783,2194,1852,5151,64077,9941,23236,27293,2822,747,5788,64748,5799,5337 PLA2G4A,PDE1B,DUSP8,PTPN21,ABHD13,LPIN3,ABHD4,ABHD6,AARS,EYA4,PPM1E,RIDA,PLPP1,CDC14B,PALD1,PPP2R2B,PDE4D,PTPRE,PGBD5,SSH3,PTPRU,PFKFB2,PTPN6,GDPD1,DNAJC6,PLPP2,NLGN4X,PXYLP1,NT5DC2,ISG20,ENPP1,PTPRJ,ENPP6,ERN1,INPP4B,DUSP19,PTPRS,ERCC5,INPP5F,PSPH,INPPL1,PTPRD,UBASH3B,OLAH,SLX1B,NOTUM,INPP1,GDPD5,PGAP1,CA2,APLF,BCHE,PDE10A,FIG4,NCEH1,ESD,CHRM3,SMPDL3A,DUSP1,CES3,PFKFB4,PPP1R3D,PTPN13,FASN,DUSP9,PDE8A,LHPP,EXOG,PLCB1,SMPDL3B,GPLD1,DAGLA,PTPRC,PLPPR2,PTPRN2,PLD1 GO:0016661 oxidoreductase activity, acting on other nitrogenous compounds as donors 0.401427725138241 -0.912727773908434 5 1 0.000595238095238095 1680 17224 875 CBS GO:0043008 ATP-dependent protein binding 0.401427725138241 -0.912727773908434 5 1 0.000595238095238095 1680 17224 10769 PLK2 GO:0048495 Roundabout binding 0.401427725138241 -0.912727773908434 5 1 0.000595238095238095 1680 17224 9353 SLIT2 GO:0022849 glutamate-gated calcium ion channel activity 0.401427725138241 -0.912727773908434 5 1 0.000595238095238095 1680 17224 2906 GRIN2D GO:0001727 lipid kinase activity 0.401427725138241 -0.912727773908434 5 1 0.000595238095238095 1680 17224 5287 PIK3C2B GO:0051429 corticotropin-releasing hormone receptor binding 0.401427725138241 -0.912727773908434 5 1 0.000595238095238095 1680 17224 2775 GNAO1 GO:0035620 ceramide transporter activity 0.401427725138241 -0.912727773908434 5 1 0.000595238095238095 1680 17224 5360 PLTP GO:0035671 enone reductase activity 0.401427725138241 -0.912727773908434 5 1 0.000595238095238095 1680 17224 79644 SRD5A3 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity 0.401427725138241 -0.912727773908434 5 1 0.000595238095238095 1680 17224 54947 LPCAT2 GO:0097677 STAT family protein binding 0.401427725138241 -0.912727773908434 5 1 0.000595238095238095 1680 17224 83666 PARP9 GO:0050145 nucleoside phosphate kinase activity 0.401427725138241 -0.912727773908434 5 1 0.000595238095238095 1680 17224 205 AK4 GO:0015186 L-glutamine transmembrane transporter activity 0.401427725138241 -0.912727773908434 5 1 0.000595238095238095 1680 17224 6510 SLC1A5 GO:0050544 arachidonic acid binding 0.401427725138241 -0.912727773908434 5 1 0.000595238095238095 1680 17224 241 ALOX5AP GO:0038100 nodal binding 0.401427725138241 -0.912727773908434 5 1 0.000595238095238095 1680 17224 130399 ACVR1C GO:0043559 insulin binding 0.401427725138241 -0.912727773908434 5 1 0.000595238095238095 1680 17224 3480 IGF1R GO:0019863 IgE binding 0.401427725138241 -0.912727773908434 5 1 0.000595238095238095 1680 17224 3958 LGALS3 GO:0005134 interleukin-2 receptor binding 0.401427725138241 -0.912727773908434 5 1 0.000595238095238095 1680 17224 2625 GATA3 GO:0051380 norepinephrine binding 0.401427725138241 -0.912727773908434 5 1 0.000595238095238095 1680 17224 153 ADRB1 GO:0031013 troponin I binding 0.401427725138241 -0.912727773908434 5 1 0.000595238095238095 1680 17224 11123 RCAN3 GO:0098639 collagen binding involved in cell-matrix adhesion 0.401427725138241 -0.912727773908434 5 1 0.000595238095238095 1680 17224 3673 ITGA2 GO:0008310 single-stranded DNA 3'-5' exodeoxyribonuclease activity 0.401427725138241 -0.912727773908434 5 1 0.000595238095238095 1680 17224 3669 ISG20 GO:0071532 ankyrin repeat binding 0.401427725138241 -0.912727773908434 5 1 0.000595238095238095 1680 17224 85456 TNKS1BP1 GO:0000268 peroxisome targeting sequence binding 0.401427725138241 -0.912727773908434 5 1 0.000595238095238095 1680 17224 51555 PEX5L GO:0001875 lipopolysaccharide receptor activity 0.401427725138241 -0.912727773908434 5 1 0.000595238095238095 1680 17224 7099 TLR4 GO:0031694 alpha-2A adrenergic receptor binding 0.401427725138241 -0.912727773908434 5 1 0.000595238095238095 1680 17224 153 ADRB1 GO:0035673 oligopeptide transmembrane transporter activity 0.401427725138241 -0.912727773908434 5 1 0.000595238095238095 1680 17224 1015 CDH17 GO:0043120 tumor necrosis factor binding 0.401427725138241 -0.912727773908434 5 1 0.000595238095238095 1680 17224 7132 TNFRSF1A GO:0048248 CXCR3 chemokine receptor binding 0.401427725138241 -0.912727773908434 5 1 0.000595238095238095 1680 17224 3627 CXCL10 GO:0004499 N,N-dimethylaniline monooxygenase activity 0.401427725138241 -0.912727773908434 5 1 0.000595238095238095 1680 17224 2329 FMO4 GO:0016416 O-palmitoyltransferase activity 0.401427725138241 -0.912727773908434 5 1 0.000595238095238095 1680 17224 9227 LRAT GO:0004614 phosphoglucomutase activity 0.401427725138241 -0.912727773908434 5 1 0.000595238095238095 1680 17224 283209 PGM2L1 GO:0042030 ATPase inhibitor activity 0.401427725138241 -0.912727773908434 5 1 0.000595238095238095 1680 17224 93974 ATP5IF1 GO:0097109 neuroligin family protein binding 0.401427725138241 -0.912727773908434 5 1 0.000595238095238095 1680 17224 9378 NRXN1 GO:0030976 thiamine pyrophosphate binding 0.401427725138241 -0.912727773908434 5 1 0.000595238095238095 1680 17224 55753 OGDHL GO:0019960 C-X3-C chemokine binding 0.401427725138241 -0.912727773908434 5 1 0.000595238095238095 1680 17224 3690 ITGB3 GO:0008142 oxysterol binding 0.401427725138241 -0.912727773908434 5 1 0.000595238095238095 1680 17224 114879 OSBPL5 GO:0016531 copper chaperone activity 0.401427725138241 -0.912727773908434 5 1 0.000595238095238095 1680 17224 475 ATOX1 GO:0070915 lysophosphatidic acid receptor activity 0.401427725138241 -0.912727773908434 5 1 0.000595238095238095 1680 17224 9170 LPAR2 GO:0043813 phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity 0.401427725138241 -0.912727773908434 5 1 0.000595238095238095 1680 17224 9896 FIG4 GO:1990254 keratin filament binding 0.401427725138241 -0.912727773908434 5 1 0.000595238095238095 1680 17224 7431 VIM GO:0070061 fructose binding 0.401427725138241 -0.912727773908434 5 1 0.000595238095238095 1680 17224 226 ALDOA GO:1904047 S-adenosyl-L-methionine binding 0.401427725138241 -0.912727773908434 5 1 0.000595238095238095 1680 17224 875 CBS GO:0005127 ciliary neurotrophic factor receptor binding 0.401427725138241 -0.912727773908434 5 1 0.000595238095238095 1680 17224 3977 LIFR GO:0086075 gap junction channel activity involved in cardiac conduction electrical coupling 0.401427725138241 -0.912727773908434 5 1 0.000595238095238095 1680 17224 10052 GJC1 GO:0046974 histone methyltransferase activity (H3-K9 specific) 0.401427725138241 -0.912727773908434 5 1 0.000595238095238095 1680 17224 83852 SETDB2 GO:0009008 DNA-methyltransferase activity 0.401427725138241 -0.912727773908434 5 1 0.000595238095238095 1680 17224 4255 MGMT GO:0030492 hemoglobin binding 0.401427725138241 -0.912727773908434 5 1 0.000595238095238095 1680 17224 3046 HBE1 GO:0071558 histone demethylase activity (H3-K27 specific) 0.401427725138241 -0.912727773908434 5 1 0.000595238095238095 1680 17224 80853 KDM7A GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity 0.402707032017462 -0.909545949103209 14 2 0.00119047619047619 1680 17224 5153,10846 PDE1B,PDE10A GO:0031005 filamin binding 0.402707032017462 -0.909545949103209 14 2 0.00119047619047619 1680 17224 171024,91147 SYNPO2,TMEM67 GO:0009881 photoreceptor activity 0.402707032017462 -0.909545949103209 14 2 0.00119047619047619 1680 17224 6785,23596 ELOVL4,OPN3 GO:0008499 UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity 0.402707032017462 -0.909545949103209 14 2 0.00119047619047619 1680 17224 8708,8707 B3GALT1,B3GALT2 GO:0005388 calcium-transporting ATPase activity 0.402707032017462 -0.909545949103209 14 2 0.00119047619047619 1680 17224 493,490 ATP2B4,ATP2B1 GO:0015172 acidic amino acid transmembrane transporter activity 0.402707032017462 -0.909545949103209 14 2 0.00119047619047619 1680 17224 6507,23657 SLC1A3,SLC7A11 GO:0016671 oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor 0.402707032017462 -0.909545949103209 14 2 0.00119047619047619 1680 17224 253827,56605 MSRB3,ERO1B GO:0010314 phosphatidylinositol-5-phosphate binding 0.402707032017462 -0.909545949103209 14 2 0.00119047619047619 1680 17224 285590,54477 SH3PXD2B,PLEKHA5 GO:0004559 alpha-mannosidase activity 0.402707032017462 -0.909545949103209 14 2 0.00119047619047619 1680 17224 23324,80267 MAN2B2,EDEM3 GO:0045504 dynein heavy chain binding 0.402707032017462 -0.909545949103209 14 2 0.00119047619047619 1680 17224 1780,51626 DYNC1I1,DYNC2LI1 GO:0005313 L-glutamate transmembrane transporter activity 0.402707032017462 -0.909545949103209 14 2 0.00119047619047619 1680 17224 6507,23657 SLC1A3,SLC7A11 GO:0015347 sodium-independent organic anion transmembrane transporter activity 0.404059671602103 -0.906192709942447 33 4 0.00238095238095238 1680 17224 81796,353189,51310,28232 SLCO5A1,SLCO4C1,SLC22A17,SLCO3A1 GO:0051393 alpha-actinin binding 0.404059671602103 -0.906192709942447 33 4 0.00238095238095238 1680 17224 9172,171024,3781,23022 MYOM2,SYNPO2,KCNN2,PALLD GO:0030291 protein serine/threonine kinase inhibitor activity 0.404059671602103 -0.906192709942447 33 4 0.00238095238095238 1680 17224 5577,10253,5569,2810 PRKAR2B,SPRY2,PKIA,SFN GO:0016303 1-phosphatidylinositol-3-kinase activity 0.410884090666647 -0.889444122103121 43 5 0.00297619047619048 1680 17224 2264,8660,5287,8822,2260 FGFR4,IRS2,PIK3C2B,FGF17,FGFR1 GO:0008022 protein C-terminus binding 0.412914694503192 -0.884514258195396 152 16 0.00952380952380952 1680 17224 3397,2335,1112,10413,7431,114327,481,29899,10458,9454,3839,7015,10612,23426,8777,55137 ID1,FN1,FOXN3,YAP1,VIM,EFHC1,ATP1B1,GPSM2,BAIAP2,HOMER3,KPNA3,TERT,TRIM3,GRIP1,MPDZ,FIGN GO:0030371 translation repressor activity 0.419354876181702 -0.869037757667247 24 3 0.00178571428571429 1680 17224 400961,1978,64506 PAIP2B,EIF4EBP1,CPEB1 GO:0042562 hormone binding 0.422321833176045 -0.861987617748679 93 10 0.00595238095238095 1680 17224 30061,90,1138,3480,2690,10203,8973,5021,1131,478 SLC40A1,ACVR1,CHRNA5,IGF1R,GHR,CALCRL,CHRNA6,OXTR,CHRM3,ATP1A3 GO:0048487 beta-tubulin binding 0.426804332552283 -0.851429608358913 34 4 0.00238095238095238 1680 17224 2258,79739,23710,6622 FGF13,TTLL7,GABARAPL1,SNCA GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific DNA binding 0.426804332552283 -0.851429608358913 34 4 0.00238095238095238 1680 17224 100271849,5966,4208,4779 MEF2B,REL,MEF2C,NFE2L1 GO:0015485 cholesterol binding 0.43081439532577 -0.842077918924455 44 5 0.00297619047619048 1680 17224 10577,8435,134429,114879,9619 NPC2,SOAT2,STARD4,OSBPL5,ABCG1 GO:0004812 aminoacyl-tRNA ligase activity 0.43081439532577 -0.842077918924455 44 5 0.00297619047619048 1680 17224 833,4141,2617,16,7453 CARS,MARS,GARS,AARS,WARS GO:0016875 ligase activity, forming carbon-oxygen bonds 0.43081439532577 -0.842077918924455 44 5 0.00297619047619048 1680 17224 833,4141,2617,16,7453 CARS,MARS,GARS,AARS,WARS GO:0004180 carboxypeptidase activity 0.43081439532577 -0.842077918924455 44 5 0.00297619047619048 1680 17224 119587,54504,1363,5547,1515 CPXM2,CPVL,CPE,PRCP,CTSV GO:0005044 scavenger receptor activity 0.433145570243982 -0.83668141753891 54 6 0.00357142857142857 1680 17224 5167,84171,8492,619207,91179,4481 ENPP1,LOXL4,PRSS12,SCART1,SCARF2,MSR1 GO:0016209 antioxidant activity 0.43573398807489 -0.830723340925784 84 9 0.00535714285714286 1680 17224 83667,2946,241,119391,4259,9446,26034,27244,114112 SESN2,GSTM2,ALOX5AP,GSTO2,MGST3,GSTO1,IPCEF1,SESN1,TXNRD3 GO:0019955 cytokine binding 0.435825565941548 -0.830513193801419 104 11 0.00654761904761905 1680 17224 4681,90,7049,10626,659,8322,2633,3690,7132,8829,8792 NBL1,ACVR1,TGFBR3,TRIM16,BMPR2,FZD4,GBP1,ITGB3,TNFRSF1A,NRP1,TNFRSF11A GO:0072349 modified amino acid transmembrane transporter activity 0.437803417003487 -0.825985288982109 15 2 0.00119047619047619 1680 17224 23657,10560 SLC7A11,SLC19A2 GO:0015923 mannosidase activity 0.437803417003487 -0.825985288982109 15 2 0.00119047619047619 1680 17224 23324,80267 MAN2B2,EDEM3 GO:0061659 ubiquitin-like protein ligase activity 0.437821862236651 -0.825943158555762 235 24 0.0142857142857143 1680 17224 91694,5071,153830,9781,26272,57520,51191,54941,11237,55008,22838,4734,143279,285671,154214,57161,10612,9443,64219,79845,143384,8945,220441,57531 LONRF1,PRKN,RNF145,RNF144A,FBXO4,HECW2,HERC5,RNF125,RNF24,HERC6,RNF44,NEDD4,HECTD2,RNF180,RNF217,PELI2,TRIM3,MED7,PJA1,RNF122,CACUL1,BTRC,RNF152,HACE1 GO:0051019 mitogen-activated protein kinase binding 0.446159074070822 -0.807079722232869 25 3 0.00178571428571429 1680 17224 9261,148252,5795 MAPKAPK2,DIRAS1,PTPRJ GO:0000030 mannosyltransferase activity 0.446159074070822 -0.807079722232869 25 3 0.00178571428571429 1680 17224 283417,200810,440138 DPY19L2,ALG1L,ALG11 GO:0015078 proton transmembrane transporter activity 0.447113853519226 -0.804942010941032 125 13 0.00773809523809524 1680 17224 56901,55002,206358,285335,5002,11182,90423,154091,114134,85414,150159,92270,84679 NDUFA4L2,TMCO3,SLC36A1,SLC9C1,SLC22A18,SLC2A6,ATP6V1E2,SLC2A12,SLC2A13,SLC45A3,SLC9B1,ATP6AP1L,SLC9A7 GO:0016790 thiolester hydrolase activity 0.449317914669104 -0.800024591301386 35 4 0.00238095238095238 1680 17224 2098,55301,84945,2194 ESD,OLAH,ABHD13,FASN GO:0008509 anion transmembrane transporter activity 0.450312291001128 -0.797813956908036 348 35 0.0208333333333333 1680 17224 55129,256987,6536,2561,2566,120103,2570,9990,6507,6542,10560,28232,51310,23657,6567,347735,220963,55117,353189,6520,10257,54020,11001,23507,206358,94015,1244,6541,84879,8140,81796,55356,6510,117247,8501 ANO10,SERINC5,SLC6A9,GABRB2,GABRG2,SLC36A4,GABRR2,SLC12A6,SLC1A3,SLC7A2,SLC19A2,SLCO3A1,SLC22A17,SLC7A11,SLC16A2,SERINC2,SLC16A9,SLC6A15,SLCO4C1,SLC3A2,ABCC4,SLC37A1,SLC27A2,LRRC8B,SLC36A1,TTYH2,ABCC2,SLC7A1,MFSD2A,SLC7A5,SLCO5A1,SLC22A15,SLC1A5,SLC16A10,SLC43A1 GO:0070405 ammonium ion binding 0.450574650053914 -0.797231510769133 75 8 0.00476190476190476 1680 17224 8973,3512,3363,1138,590,5360,1131,10125 CHRNA6,JCHAIN,HTR7,CHRNA5,BCHE,PLTP,CHRM3,RASGRP1 GO:0016706 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors 0.450600269084709 -0.797174653814379 45 5 0.00297619047619048 1680 17224 80853,5033,5352,444,8974 KDM7A,P4HA1,PLOD2,ASPH,P4HA2 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity 0.459828411679391 -0.77690187717583 6 1 0.000595238095238095 1680 17224 6489 ST8SIA1 GO:0046975 histone methyltransferase activity (H3-K36 specific) 0.459828411679391 -0.77690187717583 6 1 0.000595238095238095 1680 17224 64324 NSD1 GO:0017040 N-acylsphingosine amidohydrolase activity 0.459828411679391 -0.77690187717583 6 1 0.000595238095238095 1680 17224 340485 ACER2 GO:0046870 cadmium ion binding 0.459828411679391 -0.77690187717583 6 1 0.000595238095238095 1680 17224 4846 NOS3 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity 0.459828411679391 -0.77690187717583 6 1 0.000595238095238095 1680 17224 5337 PLD1 GO:0034594 phosphatidylinositol trisphosphate phosphatase activity 0.459828411679391 -0.77690187717583 6 1 0.000595238095238095 1680 17224 3636 INPPL1 GO:0004645 phosphorylase activity 0.459828411679391 -0.77690187717583 6 1 0.000595238095238095 1680 17224 1890 TYMP GO:0017108 5'-flap endonuclease activity 0.459828411679391 -0.77690187717583 6 1 0.000595238095238095 1680 17224 79008 SLX1B GO:0034040 lipid-transporting ATPase activity 0.459828411679391 -0.77690187717583 6 1 0.000595238095238095 1680 17224 9619 ABCG1 GO:0003958 NADPH-hemoprotein reductase activity 0.459828411679391 -0.77690187717583 6 1 0.000595238095238095 1680 17224 4846 NOS3 GO:0004064 arylesterase activity 0.459828411679391 -0.77690187717583 6 1 0.000595238095238095 1680 17224 760 CA2 GO:1903763 gap junction channel activity involved in cell communication by electrical coupling 0.459828411679391 -0.77690187717583 6 1 0.000595238095238095 1680 17224 10052 GJC1 GO:0043237 laminin-1 binding 0.459828411679391 -0.77690187717583 6 1 0.000595238095238095 1680 17224 9353 SLIT2 GO:0050815 phosphoserine residue binding 0.459828411679391 -0.77690187717583 6 1 0.000595238095238095 1680 17224 4734 NEDD4 GO:0016907 G-protein coupled acetylcholine receptor activity 0.459828411679391 -0.77690187717583 6 1 0.000595238095238095 1680 17224 1131 CHRM3 GO:0050542 icosanoid binding 0.459828411679391 -0.77690187717583 6 1 0.000595238095238095 1680 17224 241 ALOX5AP GO:0034513 box H/ACA snoRNA binding 0.459828411679391 -0.77690187717583 6 1 0.000595238095238095 1680 17224 55651 NHP2 GO:0042609 CD4 receptor binding 0.459828411679391 -0.77690187717583 6 1 0.000595238095238095 1680 17224 57088 PLSCR4 GO:0045545 syndecan binding 0.459828411679391 -0.77690187717583 6 1 0.000595238095238095 1680 17224 10855 HPSE GO:0008131 primary amine oxidase activity 0.459828411679391 -0.77690187717583 6 1 0.000595238095238095 1680 17224 4128 MAOA GO:0031849 olfactory receptor binding 0.459828411679391 -0.77690187717583 6 1 0.000595238095238095 1680 17224 65055 REEP1 GO:0097642 calcitonin family receptor activity 0.459828411679391 -0.77690187717583 6 1 0.000595238095238095 1680 17224 10203 CALCRL GO:0030620 U2 snRNA binding 0.459828411679391 -0.77690187717583 6 1 0.000595238095238095 1680 17224 3669 ISG20 GO:0000155 phosphorelay sensor kinase activity 0.459828411679391 -0.77690187717583 6 1 0.000595238095238095 1680 17224 27133 KCNH5 GO:0016778 diphosphotransferase activity 0.459828411679391 -0.77690187717583 6 1 0.000595238095238095 1680 17224 27010 TPK1 GO:0016174 NAD(P)H oxidase activity 0.459828411679391 -0.77690187717583 6 1 0.000595238095238095 1680 17224 8564 KMO GO:0004528 phosphodiesterase I activity 0.459828411679391 -0.77690187717583 6 1 0.000595238095238095 1680 17224 5167 ENPP1 GO:0048406 nerve growth factor binding 0.459828411679391 -0.77690187717583 6 1 0.000595238095238095 1680 17224 5046 PCSK6 GO:0090599 alpha-glucosidase activity 0.459828411679391 -0.77690187717583 6 1 0.000595238095238095 1680 17224 178 AGL GO:1903136 cuprous ion binding 0.459828411679391 -0.77690187717583 6 1 0.000595238095238095 1680 17224 6622 SNCA GO:0034511 U3 snoRNA binding 0.459828411679391 -0.77690187717583 6 1 0.000595238095238095 1680 17224 3669 ISG20 GO:1990239 steroid hormone binding 0.459828411679391 -0.77690187717583 6 1 0.000595238095238095 1680 17224 478 ATP1A3 GO:0140035 ubiquitination-like modification-dependent protein binding 0.459828411679391 -0.77690187717583 6 1 0.000595238095238095 1680 17224 199990 FAAP20 GO:0050543 icosatetraenoic acid binding 0.459828411679391 -0.77690187717583 6 1 0.000595238095238095 1680 17224 241 ALOX5AP GO:0004969 histamine receptor activity 0.459828411679391 -0.77690187717583 6 1 0.000595238095238095 1680 17224 51222 ZNF219 GO:0005499 vitamin D binding 0.459828411679391 -0.77690187717583 6 1 0.000595238095238095 1680 17224 10265 IRX5 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity 0.459828411679391 -0.77690187717583 6 1 0.000595238095238095 1680 17224 256435 ST6GALNAC3 GO:0004957 prostaglandin E receptor activity 0.459828411679391 -0.77690187717583 6 1 0.000595238095238095 1680 17224 3248 HPGD GO:0140036 ubiquitin-dependent protein binding 0.459828411679391 -0.77690187717583 6 1 0.000595238095238095 1680 17224 199990 FAAP20 GO:0005280 amino acid:proton symporter activity 0.459828411679391 -0.77690187717583 6 1 0.000595238095238095 1680 17224 206358 SLC36A1 GO:0005432 calcium:sodium antiporter activity 0.459828411679391 -0.77690187717583 6 1 0.000595238095238095 1680 17224 6520 SLC3A2 GO:0042626 ATPase activity, coupled to transmembrane movement of substances 0.460172857606251 -0.776153082680749 116 12 0.00714285714285714 1680 17224 10257,23461,540,10396,90423,1244,481,92270,490,493,478,9619 ABCC4,ABCA5,ATP7B,ATP8A1,ATP6V1E2,ABCC2,ATP1B1,ATP6AP1L,ATP2B1,ATP2B4,ATP1A3,ABCG1 GO:0016462 pyrophosphatase activity 0.462547156740915 -0.77100676670638 890 88 0.0523809523809524 1680 17224 92170,57530,170685,26052,29984,3798,10396,4430,51175,23046,83594,5881,91351,10382,8153,1768,5911,25837,140469,22989,2272,379,5874,1767,3306,92270,51062,2617,7846,10257,120892,1244,481,23682,57205,2770,953,5167,57089,2633,540,148252,144132,5413,27314,58528,4642,9886,10079,90423,65997,402,3800,51655,122622,5217,1780,26038,1938,23461,23551,2963,79659,4646,55137,22800,55964,490,5865,23433,4651,51560,389643,116986,64077,23250,55760,390,2775,51626,11031,55605,2669,23095,493,478,200035,9619 MTG1,CGN,NUDT10,DNM3,RHOD,KIF5A,ATP8A1,MYO1B,TUBE1,KIF21B,NUDT12,RAC3,DDX60L,TUBB4A,RND2,DNAH6,RAP2A,RAB26,MYO3B,MYH15,FHIT,ARL4D,RAB27B,DNAH5,HSPA2,ATP6AP1L,ATL1,GARS,TUBA1A,ABCC4,LRRK2,ABCC2,ATP1B1,RAB38,ATP10D,GNAI1,ENTPD1,ENPP1,ENTPD7,GBP1,ATP7B,DIRAS1,DNHD1,SEPT5,RAB30,RRAGD,MYO1D,RHOBTB1,ATP9A,ATP6V1E2,RASL11B,ARL2,KIF5C,RASD1,ADSSL1,PFN2,DYNC1I1,CHD5,EEF2,ABCA5,RASD2,GTF2F2,DYNC2H1,MYO6,FIGN,RRAS2,SEPT3,ATP2B1,RAB3B,RHOQ,MYO10,RAB6B,NUGGC,AGAP2,LHPP,ATP11A,DHX32,RND3,GNAO1,DYNC2LI1,RAB31,KIF21A,GEM,KIF1B,ATP2B4,ATP1A3,NUDT17,ABCG1 GO:0016614 oxidoreductase activity, acting on CH-OH group of donors 0.468886762567994 -0.757393984106176 137 14 0.00833333333333333 1680 17224 1962,10257,7881,7358,1718,56898,2194,3248,1488,130752,26227,197257,51084,3156 EHHADH,ABCC4,KCNAB1,UGDH,DHCR24,BDH2,FASN,HPGD,CTBP2,MDH1B,PHGDH,LDHD,CRYL1,HMGCR GO:0004864 protein phosphatase inhibitor activity 0.471541178790551 -0.751748845005198 36 4 0.00238095238095238 1680 17224 116154,9749,9858,91272 PHACTR3,PHACTR2,PPP1R26,BOD1 GO:0043531 ADP binding 0.471541178790551 -0.751748845005198 36 4 0.00238095238095238 1680 17224 5028,4646,2081,9619 P2RY1,MYO6,ERN1,ABCG1 GO:0099528 G-protein coupled neurotransmitter receptor activity 0.471541178790551 -0.751748845005198 36 4 0.00238095238095238 1680 17224 3363,51222,390442,1131 HTR7,ZNF219,OR11H4,CHRM3 GO:0016817 hydrolase activity, acting on acid anhydrides 0.471556603496172 -0.751716134281215 892 88 0.0523809523809524 1680 17224 92170,57530,170685,26052,29984,3798,10396,4430,51175,23046,83594,5881,91351,10382,8153,1768,5911,25837,140469,22989,2272,379,5874,1767,3306,92270,51062,2617,7846,10257,120892,1244,481,23682,57205,2770,953,5167,57089,2633,540,148252,144132,5413,27314,58528,4642,9886,10079,90423,65997,402,3800,51655,122622,5217,1780,26038,1938,23461,23551,2963,79659,4646,55137,22800,55964,490,5865,23433,4651,51560,389643,116986,64077,23250,55760,390,2775,51626,11031,55605,2669,23095,493,478,200035,9619 MTG1,CGN,NUDT10,DNM3,RHOD,KIF5A,ATP8A1,MYO1B,TUBE1,KIF21B,NUDT12,RAC3,DDX60L,TUBB4A,RND2,DNAH6,RAP2A,RAB26,MYO3B,MYH15,FHIT,ARL4D,RAB27B,DNAH5,HSPA2,ATP6AP1L,ATL1,GARS,TUBA1A,ABCC4,LRRK2,ABCC2,ATP1B1,RAB38,ATP10D,GNAI1,ENTPD1,ENPP1,ENTPD7,GBP1,ATP7B,DIRAS1,DNHD1,SEPT5,RAB30,RRAGD,MYO1D,RHOBTB1,ATP9A,ATP6V1E2,RASL11B,ARL2,KIF5C,RASD1,ADSSL1,PFN2,DYNC1I1,CHD5,EEF2,ABCA5,RASD2,GTF2F2,DYNC2H1,MYO6,FIGN,RRAS2,SEPT3,ATP2B1,RAB3B,RHOQ,MYO10,RAB6B,NUGGC,AGAP2,LHPP,ATP11A,DHX32,RND3,GNAO1,DYNC2LI1,RAB31,KIF21A,GEM,KIF1B,ATP2B4,ATP1A3,NUDT17,ABCG1 GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 0.471556603496172 -0.751716134281215 892 88 0.0523809523809524 1680 17224 92170,57530,170685,26052,29984,3798,10396,4430,51175,23046,83594,5881,91351,10382,8153,1768,5911,25837,140469,22989,2272,379,5874,1767,3306,92270,51062,2617,7846,10257,120892,1244,481,23682,57205,2770,953,5167,57089,2633,540,148252,144132,5413,27314,58528,4642,9886,10079,90423,65997,402,3800,51655,122622,5217,1780,26038,1938,23461,23551,2963,79659,4646,55137,22800,55964,490,5865,23433,4651,51560,389643,116986,64077,23250,55760,390,2775,51626,11031,55605,2669,23095,493,478,200035,9619 MTG1,CGN,NUDT10,DNM3,RHOD,KIF5A,ATP8A1,MYO1B,TUBE1,KIF21B,NUDT12,RAC3,DDX60L,TUBB4A,RND2,DNAH6,RAP2A,RAB26,MYO3B,MYH15,FHIT,ARL4D,RAB27B,DNAH5,HSPA2,ATP6AP1L,ATL1,GARS,TUBA1A,ABCC4,LRRK2,ABCC2,ATP1B1,RAB38,ATP10D,GNAI1,ENTPD1,ENPP1,ENTPD7,GBP1,ATP7B,DIRAS1,DNHD1,SEPT5,RAB30,RRAGD,MYO1D,RHOBTB1,ATP9A,ATP6V1E2,RASL11B,ARL2,KIF5C,RASD1,ADSSL1,PFN2,DYNC1I1,CHD5,EEF2,ABCA5,RASD2,GTF2F2,DYNC2H1,MYO6,FIGN,RRAS2,SEPT3,ATP2B1,RAB3B,RHOQ,MYO10,RAB6B,NUGGC,AGAP2,LHPP,ATP11A,DHX32,RND3,GNAO1,DYNC2LI1,RAB31,KIF21A,GEM,KIF1B,ATP2B4,ATP1A3,NUDT17,ABCG1 GO:0022848 acetylcholine-gated cation-selective channel activity 0.471740100157192 -0.751327080312037 16 2 0.00119047619047619 1680 17224 8973,1138 CHRNA6,CHRNA5 GO:0016500 protein-hormone receptor activity 0.471740100157192 -0.751327080312037 16 2 0.00119047619047619 1680 17224 55366,7253 LGR4,TSHR GO:0030169 low-density lipoprotein particle binding 0.471740100157192 -0.751327080312037 16 2 0.00119047619047619 1680 17224 3949,4481 LDLR,MSR1 GO:0005237 inhibitory extracellular ligand-gated ion channel activity 0.471740100157192 -0.751327080312037 16 2 0.00119047619047619 1680 17224 2566,2561 GABRG2,GABRB2 GO:0070492 oligosaccharide binding 0.471740100157192 -0.751327080312037 16 2 0.00119047619047619 1680 17224 6402,285761 SELL,DCBLD1 GO:0022821 potassium ion antiporter activity 0.471740100157192 -0.751327080312037 16 2 0.00119047619047619 1680 17224 285335,84679 SLC9C1,SLC9A7 GO:0042834 peptidoglycan binding 0.471740100157192 -0.751327080312037 16 2 0.00119047619047619 1680 17224 3512,3098 JCHAIN,HK1 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process 0.471740100157192 -0.751327080312037 16 2 0.00119047619047619 1680 17224 10399,27018 RACK1,BEX3 GO:0030275 LRR domain binding 0.471740100157192 -0.751327080312037 16 2 0.00119047619047619 1680 17224 468,1649 ATF4,DDIT3 GO:0048531 beta-1,3-galactosyltransferase activity 0.471740100157192 -0.751327080312037 16 2 0.00119047619047619 1680 17224 8708,8707 B3GALT1,B3GALT2 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen 0.472453244368893 -0.749816490661211 26 3 0.00178571428571429 1680 17224 5033,6999,8974 P4HA1,TDO2,P4HA2 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding 0.472453244368893 -0.749816490661211 26 3 0.00178571428571429 1680 17224 3092,59338,9846 HIP1,PLEKHA1,GAB2 GO:0016405 CoA-ligase activity 0.472453244368893 -0.749816490661211 26 3 0.00178571428571429 1680 17224 2180,11001,6296 ACSL1,SLC27A2,ACSM3 GO:0071813 lipoprotein particle binding 0.472453244368893 -0.749816490661211 26 3 0.00178571428571429 1680 17224 3949,7436,4481 LDLR,VLDLR,MSR1 GO:0071814 protein-lipid complex binding 0.472453244368893 -0.749816490661211 26 3 0.00178571428571429 1680 17224 3949,7436,4481 LDLR,VLDLR,MSR1 GO:0071949 FAD binding 0.472453244368893 -0.749816490661211 26 3 0.00178571428571429 1680 17224 9645,8564,51700 MICAL2,KMO,CYB5R2 GO:0017171 serine hydrolase activity 0.475296055315465 -0.743817394753935 219 22 0.0130952380952381 1680 17224 57628,10279,8492,6768,720,715,2161,10584,9372,2152,54504,5547,360200,1515,649,119587,3082,57552,1363,5125,7093,5046 DPP10,PRSS16,PRSS12,ST14,C4A,C1R,F12,COLEC10,ZFYVE9,F3,CPVL,PRCP,TMPRSS9,CTSV,BMP1,CPXM2,HGF,NCEH1,CPE,PCSK5,TLL2,PCSK6 GO:0015297 antiporter activity 0.478491381145926 -0.73711708048557 87 9 0.00535714285714286 1680 17224 55002,6520,54020,23657,285335,5002,8140,150159,84679 TMCO3,SLC3A2,SLC37A1,SLC7A11,SLC9C1,SLC22A18,SLC7A5,SLC9B1,SLC9A7 GO:0003730 mRNA 3'-UTR binding 0.483422733211546 -0.726863784074324 67 7 0.00416666666666667 1680 17224 10644,8531,57060,678,64506,23367,25946 IGF2BP2,YBX3,PCBP4,ZFP36L2,CPEB1,LARP1,ZNF385A GO:0016491 oxidoreductase activity 0.483622687650401 -0.726450247259216 731 72 0.0428571428571429 1680 17224 10157,7358,1488,1592,114112,1595,7881,56605,8564,10840,4714,55240,130752,2731,1545,83667,2597,10257,51700,160428,253827,9446,27244,444,6622,5831,6999,8974,56898,5066,5033,3248,4128,113612,51084,241,1962,1573,1718,645,285440,875,6319,26227,80853,6307,79758,26034,84171,26002,55711,3156,4846,3992,56901,5768,9645,217,2946,10765,389643,4259,2194,55753,197257,26872,119391,5352,2329,79644,6713,1717 AASS,UGDH,CTBP2,CYP26A1,TXNRD3,CYP51A1,KCNAB1,ERO1B,KMO,ALDH1L1,NDUFB8,STEAP3,MDH1B,GLDC,CYP1B1,SESN2,GAPDH,ABCC4,CYB5R2,ALDH1L2,MSRB3,GSTO1,SESN1,ASPH,SNCA,PYCR1,TDO2,P4HA2,BDH2,PAM,P4HA1,HPGD,MAOA,CYP2U1,CRYL1,ALOX5AP,EHHADH,CYP2J2,DHCR24,BLVRB,CYP4V2,CBS,SCD,PHGDH,KDM7A,MSMO1,DHRS12,IPCEF1,LOXL4,MOXD1,FAR2,HMGCR,NOS3,FADS1,NDUFA4L2,QSOX1,MICAL2,ALDH2,GSTM2,KDM5B,NUGGC,MGST3,FASN,OGDHL,LDHD,STEAP1,GSTO2,PLOD2,FMO4,SRD5A3,SQLE,DHCR7 GO:0030971 receptor tyrosine kinase binding 0.486296910297823 -0.720935915082561 57 6 0.00357142857142857 1680 17224 10718,2621,10399,2888,4038,9846 NRG3,GAS6,RACK1,GRB14,LRP4,GAB2 GO:0016874 ligase activity 0.486697595498886 -0.720112302572261 159 16 0.00952380952380952 1680 17224 833,93974,2617,2180,440,57494,11001,284716,445,4141,122622,79739,16,8945,6296,7453 CARS,ATP5IF1,GARS,ACSL1,ASNS,RIMKLB,SLC27A2,RIMKLA,ASS1,MARS,ADSSL1,TTLL7,AARS,BTRC,ACSM3,WARS GO:0018024 histone-lysine N-methyltransferase activity 0.489571394412605 -0.714224975935755 47 5 0.00297619047619048 1680 17224 7468,64324,83852,64754,2122 NSD2,NSD1,SETDB2,SMYD3,MECOM GO:0001784 phosphotyrosine residue binding 0.493420752672563 -0.706393015227089 37 4 0.00238095238095238 1680 17224 2268,6452,6850,5777 FGR,SH3BP2,SYK,PTPN6 GO:0070888 E-box binding 0.493420752672563 -0.706393015227089 37 4 0.00238095238095238 1680 17224 2625,148523,63973,4609 GATA3,CIART,NEUROG2,MYC GO:0051787 misfolded protein binding 0.4981609507719 -0.696832059852434 27 3 0.00178571428571429 1680 17224 2161,3306,5611 F12,HSPA2,DNAJC3 GO:0005328 neurotransmitter:sodium symporter activity 0.4981609507719 -0.696832059852434 27 3 0.00178571428571429 1680 17224 55117,6536,6507 SLC6A15,SLC6A9,SLC1A3 GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen 0.4981609507719 -0.696832059852434 27 3 0.00178571428571429 1680 17224 5033,6999,8974 P4HA1,TDO2,P4HA2 GO:0046875 ephrin receptor binding 0.4981609507719 -0.696832059852434 27 3 0.00178571428571429 1680 17224 1948,1123,1944 EFNB2,CHN1,EFNA3 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors 0.503675589657766 -0.685822889470041 58 6 0.00357142857142857 1680 17224 1717,645,79644,1718,56898,2194 DHCR7,BLVRB,SRD5A3,DHCR24,BDH2,FASN GO:0044877 protein-containing complex binding 0.504020757086484 -0.685137827063429 971 95 0.056547619047619 1680 17224 10580,90,3949,4430,4481,5318,3512,119,4869,1488,5578,51429,7373,780,85456,55607,1794,1496,5358,85477,4072,9531,7049,25890,3690,79983,92,153090,22989,4082,26577,871,83660,7253,1285,79924,8838,11034,120892,4779,7431,481,93,23682,83700,6622,2770,8660,4088,2934,5167,644150,3071,147372,59345,3673,2887,7168,84978,4642,9902,2335,3958,3655,150356,29899,2047,23209,122622,57211,3983,1938,3480,4609,783,4646,6850,5058,167691,4651,7436,3092,5357,10399,64506,2268,2200,7060,2775,1015,6840,9172,64754,10736,57698 SORBS1,ACVR1,LDLR,MYO1B,MSR1,PKP2,JCHAIN,ADD2,NPM1,CTBP2,PRKCA,SNX9,COL14A1,DDR1,TNKS1BP1,PPP1R9A,DOCK2,CTNNA2,PLS3,SCIN,EPCAM,BAG3,TGFBR3,ABI3BP,ITGB3,POF1B,ACVR2A,DAB2IP,MYH15,MARCKS,PCOLCE2,SERPINH1,TLN2,TSHR,COL4A3,ADM2,WISP3,DSTN,LRRK2,NFE2L1,VIM,ATP1B1,ACVR2B,RAB38,JAM3,SNCA,GNAI1,IRS2,SMAD3,GSN,ENPP1,WIPF3,NCKAP1L,CCBE1,GNB4,ITGA2,GRB10,TPM1,FRMD5,MYO1D,MRC2,FN1,LGALS3,ITGA6,CHADL,GPSM2,EPHB1,MLC1,ADSSL1,ADGRG6,ABLIM1,EEF2,IGF1R,MYC,CACNB2,MYO6,SYK,PAK1,LCA5,MYO10,VLDLR,HIP1,PLS1,RACK1,CPEB1,FGR,FBN1,THBS4,GNAO1,CDH17,SVIL,MYOM2,SMYD3,SIX2,SHTN1 GO:0016307 phosphatidylinositol phosphate kinase activity 0.504409351026352 -0.684367136152922 17 2 0.00119047619047619 1680 17224 138429,5287 PIP5KL1,PIK3C2B GO:0015095 magnesium ion transmembrane transporter activity 0.504409351026352 -0.684367136152922 17 2 0.00119047619047619 1680 17224 54805,79815 CNNM2,NIPAL2 GO:0016722 oxidoreductase activity, oxidizing metal ions 0.504409351026352 -0.684367136152922 17 2 0.00119047619047619 1680 17224 55240,26872 STEAP3,STEAP1 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 0.508729727648948 -0.675838390392334 120 12 0.00714285714285714 1680 17224 1962,10257,7881,7358,56898,2194,3248,1488,130752,26227,3156,51084 EHHADH,ABCC4,KCNAB1,UGDH,BDH2,FASN,HPGD,CTBP2,MDH1B,PHGDH,HMGCR,CRYL1 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity 0.512534200289144 -0.668387837924572 7 1 0.000595238095238095 1680 17224 10718 NRG3 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity 0.512534200289144 -0.668387837924572 7 1 0.000595238095238095 1680 17224 217 ALDH2 GO:0005000 vasopressin receptor activity 0.512534200289144 -0.668387837924572 7 1 0.000595238095238095 1680 17224 5021 OXTR GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity 0.512534200289144 -0.668387837924572 7 1 0.000595238095238095 1680 17224 138429 PIP5KL1 GO:0008430 selenium binding 0.512534200289144 -0.668387837924572 7 1 0.000595238095238095 1680 17224 6414 SELENOP GO:0120013 intermembrane lipid transfer activity 0.512534200289144 -0.668387837924572 7 1 0.000595238095238095 1680 17224 84725 PLEKHA8 GO:0002151 G-quadruplex RNA binding 0.512534200289144 -0.668387837924572 7 1 0.000595238095238095 1680 17224 2334 AFF2 GO:0015501 glutamate:sodium symporter activity 0.512534200289144 -0.668387837924572 7 1 0.000595238095238095 1680 17224 6507 SLC1A3 GO:0019784 NEDD8-specific protease activity 0.512534200289144 -0.668387837924572 7 1 0.000595238095238095 1680 17224 7347 UCHL3 GO:0000405 bubble DNA binding 0.512534200289144 -0.668387837924572 7 1 0.000595238095238095 1680 17224 2073 ERCC5 GO:0004321 fatty-acyl-CoA synthase activity 0.512534200289144 -0.668387837924572 7 1 0.000595238095238095 1680 17224 6296 ACSM3 GO:0016833 oxo-acid-lyase activity 0.512534200289144 -0.668387837924572 7 1 0.000595238095238095 1680 17224 171425 CLYBL GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H 0.512534200289144 -0.668387837924572 7 1 0.000595238095238095 1680 17224 51700 CYB5R2 GO:0004691 cAMP-dependent protein kinase activity 0.512534200289144 -0.668387837924572 7 1 0.000595238095238095 1680 17224 5567 PRKACB GO:0032051 clathrin light chain binding 0.512534200289144 -0.668387837924572 7 1 0.000595238095238095 1680 17224 3092 HIP1 GO:0000099 sulfur amino acid transmembrane transporter activity 0.512534200289144 -0.668387837924572 7 1 0.000595238095238095 1680 17224 23657 SLC7A11 GO:0016015 morphogen activity 0.512534200289144 -0.668387837924572 7 1 0.000595238095238095 1680 17224 4681 NBL1 GO:0004972 NMDA glutamate receptor activity 0.512534200289144 -0.668387837924572 7 1 0.000595238095238095 1680 17224 2906 GRIN2D GO:0004673 protein histidine kinase activity 0.512534200289144 -0.668387837924572 7 1 0.000595238095238095 1680 17224 27133 KCNH5 GO:0035174 histone serine kinase activity 0.512534200289144 -0.668387837924572 7 1 0.000595238095238095 1680 17224 5563 PRKAA2 GO:0016530 metallochaperone activity 0.512534200289144 -0.668387837924572 7 1 0.000595238095238095 1680 17224 475 ATOX1 GO:0042608 T cell receptor binding 0.512534200289144 -0.668387837924572 7 1 0.000595238095238095 1680 17224 1794 DOCK2 GO:0008297 single-stranded DNA exodeoxyribonuclease activity 0.512534200289144 -0.668387837924572 7 1 0.000595238095238095 1680 17224 3669 ISG20 GO:0032050 clathrin heavy chain binding 0.512534200289144 -0.668387837924572 7 1 0.000595238095238095 1680 17224 3949 LDLR GO:1901474 azole transmembrane transporter activity 0.512534200289144 -0.668387837924572 7 1 0.000595238095238095 1680 17224 10560 SLC19A2 GO:0008172 S-methyltransferase activity 0.512534200289144 -0.668387837924572 7 1 0.000595238095238095 1680 17224 4255 MGMT GO:0035374 chondroitin sulfate binding 0.512534200289144 -0.668387837924572 7 1 0.000595238095238095 1680 17224 5802 PTPRS GO:0005078 MAP-kinase scaffold activity 0.512534200289144 -0.668387837924572 7 1 0.000595238095238095 1680 17224 142679 DUSP19 GO:0005314 high-affinity glutamate transmembrane transporter activity 0.512534200289144 -0.668387837924572 7 1 0.000595238095238095 1680 17224 6507 SLC1A3 GO:0005021 vascular endothelial growth factor-activated receptor activity 0.512534200289144 -0.668387837924572 7 1 0.000595238095238095 1680 17224 8829 NRP1 GO:0098634 cell-matrix adhesion mediator activity 0.512534200289144 -0.668387837924572 7 1 0.000595238095238095 1680 17224 3673 ITGA2 GO:0001609 G-protein coupled adenosine receptor activity 0.512534200289144 -0.668387837924572 7 1 0.000595238095238095 1680 17224 5028 P2RY1 GO:0008517 folic acid transmembrane transporter activity 0.512534200289144 -0.668387837924572 7 1 0.000595238095238095 1680 17224 10560 SLC19A2 GO:0005114 type II transforming growth factor beta receptor binding 0.512534200289144 -0.668387837924572 7 1 0.000595238095238095 1680 17224 7049 TGFBR3 GO:0030235 nitric-oxide synthase regulator activity 0.512534200289144 -0.668387837924572 7 1 0.000595238095238095 1680 17224 493 ATP2B4 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity 0.512534200289144 -0.668387837924572 7 1 0.000595238095238095 1680 17224 5287 PIK3C2B GO:0003708 retinoic acid receptor activity 0.512534200289144 -0.668387837924572 7 1 0.000595238095238095 1680 17224 2104 ESRRG GO:0004457 lactate dehydrogenase activity 0.512534200289144 -0.668387837924572 7 1 0.000595238095238095 1680 17224 197257 LDHD GO:0004711 ribosomal protein S6 kinase activity 0.512534200289144 -0.668387837924572 7 1 0.000595238095238095 1680 17224 6196 RPS6KA2 GO:0016504 peptidase activator activity 0.514909019505562 -0.663765055079068 38 4 0.00238095238095238 1680 17224 10399,26577,2335,27018 RACK1,PCOLCE2,FN1,BEX3 GO:0033293 monocarboxylic acid binding 0.51535204284382 -0.662905033514139 69 7 0.00416666666666667 1680 17224 10247,3399,241,9227,1592,2172,6622 RIDA,ID3,ALOX5AP,LRAT,CYP26A1,FABP6,SNCA GO:0008236 serine-type peptidase activity 0.522375263259723 -0.649369054247258 214 21 0.0125 1680 17224 57628,10279,6768,8492,720,715,2161,10584,9372,2152,54504,5547,360200,1515,649,119587,3082,1363,5046,7093,5125 DPP10,PRSS16,ST14,PRSS12,C4A,C1R,F12,COLEC10,ZFYVE9,F3,CPVL,PRCP,TMPRSS9,CTSV,BMP1,CPXM2,HGF,CPE,PCSK6,TLL2,PCSK5 GO:0016411 acylglycerol O-acyltransferase activity 0.523217779970396 -0.647757496292716 28 3 0.00178571428571429 1680 17224 129642,54947,56895 MBOAT2,LPCAT2,AGPAT4 GO:0008374 O-acyltransferase activity 0.527494823920944 -0.639616226152203 49 5 0.00297619047619048 1680 17224 8435,129642,54947,9227,56895 SOAT2,MBOAT2,LPCAT2,LRAT,AGPAT4 GO:0032934 sterol binding 0.527494823920944 -0.639616226152203 49 5 0.00297619047619048 1680 17224 10577,8435,134429,114879,9619 NPC2,SOAT2,STARD4,OSBPL5,ABCG1 GO:0098531 transcription factor activity, direct ligand regulated sequence-specific DNA binding 0.527494823920944 -0.639616226152203 49 5 0.00297619047619048 1680 17224 3174,2649,3164,2104,6720 HNF4G,NR6A1,NR4A1,ESRRG,SREBF1 GO:0004879 nuclear receptor activity 0.527494823920944 -0.639616226152203 49 5 0.00297619047619048 1680 17224 3174,2649,3164,2104,6720 HNF4G,NR6A1,NR4A1,ESRRG,SREBF1 GO:1990782 protein tyrosine kinase binding 0.531051219692818 -0.632896803460202 70 7 0.00416666666666667 1680 17224 10718,2621,10399,2888,3556,4038,9846 NRG3,GAS6,RACK1,GRB14,IL1RAP,LRP4,GAB2 GO:0046527 glucosyltransferase activity 0.535735459388652 -0.624114785661904 18 2 0.00119047619047619 1680 17224 5352,144245 PLOD2,ALG10B GO:0001848 complement binding 0.535735459388652 -0.624114785661904 18 2 0.00119047619047619 1680 17224 1380,720 CR2,C4A GO:0005310 dicarboxylic acid transmembrane transporter activity 0.535963955720388 -0.623688366962824 39 4 0.00238095238095238 1680 17224 1244,6507,23657,10560 ABCC2,SLC1A3,SLC7A11,SLC19A2 GO:0032451 demethylase activity 0.535963955720388 -0.623688366962824 39 4 0.00238095238095238 1680 17224 1595,80853,10765,84159 CYP51A1,KDM7A,KDM5B,ARID5B GO:0003755 peptidyl-prolyl cis-trans isomerase activity 0.535963955720388 -0.623688366962824 39 4 0.00238095238095238 1680 17224 5903,11328,55033,51303 RANBP2,FKBP9,FKBP14,FKBP11 GO:0030594 neurotransmitter receptor activity 0.537120424617507 -0.621532955205768 112 11 0.00654761904761905 1680 17224 3363,2900,1138,2898,2894,8973,2566,2906,390442,51222,1131 HTR7,GRIK4,CHRNA5,GRIK2,GRID1,CHRNA6,GABRG2,GRIN2D,OR11H4,ZNF219,CHRM3 GO:0042054 histone methyltransferase activity 0.537763073931195 -0.620337198844956 60 6 0.00357142857142857 1680 17224 7468,64324,83852,64754,59336,2122 NSD2,NSD1,SETDB2,SMYD3,PRDM13,MECOM GO:0016298 lipase activity 0.539811180135444 -0.616535866987218 133 13 0.00773809523809524 1680 17224 747,5321,284161,147111,5337,57552,57406,23236,1131,10924,27293,2822,23491 DAGLA,PLA2G4A,GDPD1,NOTUM,PLD1,NCEH1,ABHD6,PLCB1,CHRM3,SMPDL3A,SMPDL3B,GPLD1,CES3 GO:0015238 drug transmembrane transporter activity 0.542159697234524 -0.61219467659747 102 10 0.00595238095238095 1680 17224 6541,6536,23657,206358,5002,120103,6507,6542,6510,10560 SLC7A1,SLC6A9,SLC7A11,SLC36A1,SLC22A18,SLC36A4,SLC1A3,SLC7A2,SLC1A5,SLC19A2 GO:0050840 extracellular matrix binding 0.545983084098769 -0.605167285221254 50 5 0.00297619047619048 1680 17224 3958,9353,57211,3673,3690 LGALS3,SLIT2,ADGRG6,ITGA2,ITGB3 GO:0043130 ubiquitin binding 0.546547538801746 -0.604133987405399 71 7 0.00416666666666667 1680 17224 4088,5071,7347,92181,4734,337867,199990 SMAD3,PRKN,UCHL3,UBTD2,NEDD4,UBAC2,FAAP20 GO:0001106 RNA polymerase II transcription corepressor activity 0.547570478538199 -0.602264097652558 29 3 0.00178571428571429 1680 17224 256536,26508,473 TCERG1L,HEYL,RERE GO:0032452 histone demethylase activity 0.547570478538199 -0.602264097652558 29 3 0.00178571428571429 1680 17224 80853,10765,84159 KDM7A,KDM5B,ARID5B GO:0004629 phospholipase C activity 0.547570478538199 -0.602264097652558 29 3 0.00178571428571429 1680 17224 147111,23236,1131 NOTUM,PLCB1,CHRM3 GO:0005496 steroid binding 0.547825955147437 -0.601797642575631 92 9 0.00535714285714286 1680 17224 10265,8435,2104,134429,114879,10577,4306,478,9619 IRX5,SOAT2,ESRRG,STARD4,OSBPL5,NPC2,NR3C2,ATP1A3,ABCG1 GO:0016279 protein-lysine N-methyltransferase activity 0.554424901873167 -0.589823915316532 61 6 0.00357142857142857 1680 17224 7468,64324,83852,399818,64754,2122 NSD2,NSD1,SETDB2,EEF1AKMT2,SMYD3,MECOM GO:0004620 phospholipase activity 0.554978254772417 -0.588826346593522 103 10 0.00595238095238095 1680 17224 5321,284161,147111,5337,57406,23236,1131,10924,27293,2822 PLA2G4A,GDPD1,NOTUM,PLD1,ABHD6,PLCB1,CHRM3,SMPDL3A,SMPDL3B,GPLD1 GO:0015405 P-P-bond-hydrolysis-driven transmembrane transporter activity 0.556051589120794 -0.586894202847449 124 12 0.00714285714285714 1680 17224 10257,23461,10396,540,90423,1244,481,92270,490,493,9619,478 ABCC4,ABCA5,ATP8A1,ATP7B,ATP6V1E2,ABCC2,ATP1B1,ATP6AP1L,ATP2B1,ATP2B4,ABCG1,ATP1A3 GO:0015399 primary active transmembrane transporter activity 0.556051589120794 -0.586894202847449 124 12 0.00714285714285714 1680 17224 10257,23461,10396,540,90423,1244,481,92270,490,493,9619,478 ABCC4,ABCA5,ATP8A1,ATP7B,ATP6V1E2,ABCC2,ATP1B1,ATP6AP1L,ATP2B1,ATP2B4,ABCG1,ATP1A3 GO:0070878 primary miRNA binding 0.560100126049403 -0.579639714718344 8 1 0.000595238095238095 1680 17224 4088 SMAD3 GO:0004415 hyalurononglucosaminidase activity 0.560100126049403 -0.579639714718344 8 1 0.000595238095238095 1680 17224 23670 CEMIP2 GO:0016413 O-acetyltransferase activity 0.560100126049403 -0.579639714718344 8 1 0.000595238095238095 1680 17224 54947 LPCAT2 GO:0004679 AMP-activated protein kinase activity 0.560100126049403 -0.579639714718344 8 1 0.000595238095238095 1680 17224 5563 PRKAA2 GO:0072542 protein phosphatase activator activity 0.560100126049403 -0.579639714718344 8 1 0.000595238095238095 1680 17224 3486 IGFBP3 GO:0030619 U1 snRNA binding 0.560100126049403 -0.579639714718344 8 1 0.000595238095238095 1680 17224 3669 ISG20 GO:0034618 arginine binding 0.560100126049403 -0.579639714718344 8 1 0.000595238095238095 1680 17224 4846 NOS3 GO:0008140 cAMP response element binding protein binding 0.560100126049403 -0.579639714718344 8 1 0.000595238095238095 1680 17224 1649 DDIT3 GO:0043208 glycosphingolipid binding 0.560100126049403 -0.579639714718344 8 1 0.000595238095238095 1680 17224 6402 SELL GO:0004300 enoyl-CoA hydratase activity 0.560100126049403 -0.579639714718344 8 1 0.000595238095238095 1680 17224 1962 EHHADH GO:0070740 tubulin-glutamic acid ligase activity 0.560100126049403 -0.579639714718344 8 1 0.000595238095238095 1680 17224 79739 TTLL7 GO:0017169 CDP-alcohol phosphatidyltransferase activity 0.560100126049403 -0.579639714718344 8 1 0.000595238095238095 1680 17224 1040 CDS1 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity 0.560100126049403 -0.579639714718344 8 1 0.000595238095238095 1680 17224 1843 DUSP1 GO:0051379 epinephrine binding 0.560100126049403 -0.579639714718344 8 1 0.000595238095238095 1680 17224 153 ADRB1 GO:0005167 neurotrophin TRK receptor binding 0.560100126049403 -0.579639714718344 8 1 0.000595238095238095 1680 17224 627 BDNF GO:0015232 heme transporter activity 0.560100126049403 -0.579639714718344 8 1 0.000595238095238095 1680 17224 55640 FLVCR2 GO:0047760 butyrate-CoA ligase activity 0.560100126049403 -0.579639714718344 8 1 0.000595238095238095 1680 17224 6296 ACSM3 GO:0031628 opioid receptor binding 0.560100126049403 -0.579639714718344 8 1 0.000595238095238095 1680 17224 2775 GNAO1 GO:0032453 histone demethylase activity (H3-K4 specific) 0.560100126049403 -0.579639714718344 8 1 0.000595238095238095 1680 17224 10765 KDM5B GO:0070739 protein-glutamic acid ligase activity 0.560100126049403 -0.579639714718344 8 1 0.000595238095238095 1680 17224 79739 TTLL7 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity 0.560100126049403 -0.579639714718344 8 1 0.000595238095238095 1680 17224 80267 EDEM3 GO:0003996 acyl-CoA ligase activity 0.560100126049403 -0.579639714718344 8 1 0.000595238095238095 1680 17224 6296 ACSM3 GO:0030368 interleukin-17 receptor activity 0.560100126049403 -0.579639714718344 8 1 0.000595238095238095 1680 17224 54756 IL17RD GO:0001849 complement component C1q binding 0.560100126049403 -0.579639714718344 8 1 0.000595238095238095 1680 17224 720 C4A GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor 0.560100126049403 -0.579639714718344 8 1 0.000595238095238095 1680 17224 5768 QSOX1 GO:0016494 C-X-C chemokine receptor activity 0.560100126049403 -0.579639714718344 8 1 0.000595238095238095 1680 17224 643 CXCR5 GO:0048256 flap endonuclease activity 0.560100126049403 -0.579639714718344 8 1 0.000595238095238095 1680 17224 79008 SLX1B GO:0051920 peroxiredoxin activity 0.560100126049403 -0.579639714718344 8 1 0.000595238095238095 1680 17224 27244 SESN1 GO:1902282 voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization 0.560100126049403 -0.579639714718344 8 1 0.000595238095238095 1680 17224 3752 KCND3 GO:0046920 alpha-(1->3)-fucosyltransferase activity 0.560100126049403 -0.579639714718344 8 1 0.000595238095238095 1680 17224 10690 FUT9 GO:0070181 small ribosomal subunit rRNA binding 0.560100126049403 -0.579639714718344 8 1 0.000595238095238095 1680 17224 6207 RPS13 GO:0051117 ATPase binding 0.561823354619681 -0.576567794119298 72 7 0.00416666666666667 1680 17224 27113,93974,481,5144,29887,287,7466 BBC3,ATP5IF1,ATP1B1,PDE4D,SNX10,ANK2,WFS1 GO:0017111 nucleoside-triphosphatase activity 0.562250739545372 -0.575807372811657 840 81 0.0482142857142857 1680 17224 92170,57530,26052,29984,3798,10396,4430,51175,23046,5881,91351,10382,8153,1768,5911,25837,140469,22989,379,5874,1767,3306,92270,51062,7846,10257,120892,1244,481,23682,57205,2770,953,57089,2633,540,148252,144132,5413,27314,58528,4642,9886,10079,90423,65997,402,3800,51655,122622,5217,1780,26038,1938,23461,23551,2963,79659,55137,4646,22800,55964,490,5865,23433,4651,51560,389643,116986,23250,55760,390,2775,51626,11031,55605,2669,23095,493,478,9619 MTG1,CGN,DNM3,RHOD,KIF5A,ATP8A1,MYO1B,TUBE1,KIF21B,RAC3,DDX60L,TUBB4A,RND2,DNAH6,RAP2A,RAB26,MYO3B,MYH15,ARL4D,RAB27B,DNAH5,HSPA2,ATP6AP1L,ATL1,TUBA1A,ABCC4,LRRK2,ABCC2,ATP1B1,RAB38,ATP10D,GNAI1,ENTPD1,ENTPD7,GBP1,ATP7B,DIRAS1,DNHD1,SEPT5,RAB30,RRAGD,MYO1D,RHOBTB1,ATP9A,ATP6V1E2,RASL11B,ARL2,KIF5C,RASD1,ADSSL1,PFN2,DYNC1I1,CHD5,EEF2,ABCA5,RASD2,GTF2F2,DYNC2H1,FIGN,MYO6,RRAS2,SEPT3,ATP2B1,RAB3B,RHOQ,MYO10,RAB6B,NUGGC,AGAP2,ATP11A,DHX32,RND3,GNAO1,DYNC2LI1,RAB31,KIF21A,GEM,KIF1B,ATP2B4,ATP1A3,ABCG1 GO:0052742 phosphatidylinositol kinase activity 0.564119039391314 -0.572489987004131 51 5 0.00297619047619048 1680 17224 2264,8660,5287,8822,2260 FGFR4,IRS2,PIK3C2B,FGF17,FGFR1 GO:0061778 intracellular chloride channel activity 0.565669519978 -0.569745258271996 19 2 0.00119047619047619 1680 17224 94015,55129 TTYH2,ANO10 GO:0005229 intracellular calcium activated chloride channel activity 0.565669519978 -0.569745258271996 19 2 0.00119047619047619 1680 17224 94015,55129 TTYH2,ANO10 GO:0016854 racemase and epimerase activity 0.565669519978 -0.569745258271996 19 2 0.00119047619047619 1680 17224 92126,26035 DSEL,GLCE GO:0050431 transforming growth factor beta binding 0.565669519978 -0.569745258271996 19 2 0.00119047619047619 1680 17224 90,7049 ACVR1,TGFBR3 GO:0016505 peptidase activator activity involved in apoptotic process 0.565669519978 -0.569745258271996 19 2 0.00119047619047619 1680 17224 10399,27018 RACK1,BEX3 GO:0008266 poly(U) RNA binding 0.565669519978 -0.569745258271996 19 2 0.00119047619047619 1680 17224 54033,202559 RBM11,KHDRBS2 GO:0030506 ankyrin binding 0.565669519978 -0.569745258271996 19 2 0.00119047619047619 1680 17224 84033,6331 OBSCN,SCN5A GO:0052689 carboxylic ester hydrolase activity 0.56803651934897 -0.565569567699329 146 14 0.00833333333333333 1680 17224 747,5321,760,590,284161,57502,147111,57552,63874,57406,2098,16,80055,23491 DAGLA,PLA2G4A,CA2,BCHE,GDPD1,NLGN4X,NOTUM,NCEH1,ABHD4,ABHD6,ESD,AARS,PGAP1,CES3 GO:0016278 lysine N-methyltransferase activity 0.570804175227307 -0.560709078712258 62 6 0.00357142857142857 1680 17224 7468,64324,83852,399818,64754,2122 NSD2,NSD1,SETDB2,EEF1AKMT2,SMYD3,MECOM GO:0031369 translation initiation factor binding 0.571176070383161 -0.560057762421227 30 3 0.00178571428571429 1680 17224 1978,23367,100127983 EIF4EBP1,LARP1,C8orf88 GO:0016878 acid-thiol ligase activity 0.571176070383161 -0.560057762421227 30 3 0.00178571428571429 1680 17224 2180,11001,6296 ACSL1,SLC27A2,ACSM3 GO:0016859 cis-trans isomerase activity 0.576632460399372 -0.55055019914428 41 4 0.00238095238095238 1680 17224 5903,11328,55033,51303 RANBP2,FKBP9,FKBP14,FKBP11 GO:0004888 transmembrane signaling receptor activity 0.581843413026617 -0.54155391723353 1227 118 0.0702380952380952 1680 17224 643,2042,90,6785,55366,2898,1951,8477,5362,10859,79339,3597,4916,780,92737,2152,2838,7098,7049,1138,51310,22859,92,2051,4233,5791,343171,7099,7253,3556,5159,8321,118429,130399,1630,10076,8322,5777,1380,8973,93,4919,26512,958,2260,25987,285601,3363,51704,26996,3673,84451,153,7132,3248,5021,657,166647,8829,219699,23266,3977,282763,81491,7301,9902,9170,659,6092,9620,60401,5789,2561,8325,4038,2566,5028,2570,8794,2047,51222,55504,8809,57211,576,2202,3480,2690,23596,4040,23554,8792,2674,23432,1131,8643,27077,2264,11245,8633,54756,51232,7436,1944,2894,10203,390442,10333,3953,2842,2861,5788,2900,391195,577,5799,2906,3581 CXCR5,EPHA3,ACVR1,ELOVL4,LGR4,GRIK2,CELSR3,GPR65,PLXNA2,LILRB1,OR51B4,IL13RA1,NTRK3,DDR1,DNER,F3,GPR15,TLR3,TGFBR3,CHRNA5,SLC22A17,ADGRL1,ACVR2A,EPHB6,MET,PTPRE,OR2W3,TLR4,TSHR,IL1RAP,PDGFRB,FZD1,ANTXR2,ACVR1C,DCC,PTPRU,FZD4,PTPN6,CR2,CHRNA6,ACVR2B,ROR1,INTS6,CD40,FGFR1,TSKU,GPR150,HTR7,GPRC5B,GPR160,ITGA2,MAP3K21,ADRB1,TNFRSF1A,HPGD,OXTR,BMPR1A,ADGRA3,NRP1,UNC5B,ADGRL2,LIFR,OR51B5,GPR63,TYRO3,MRC2,LPAR2,BMPR2,ROBO2,CELSR1,EDA2R,PTPRD,GABRB2,FZD8,LRP4,GABRG2,P2RY1,GABRR2,TNFRSF10C,EPHB1,ZNF219,TNFRSF19,IL18R1,ADGRG6,ADGRB2,EFEMP1,IGF1R,GHR,OPN3,LRP6,TSPAN12,TNFRSF11A,GFRA1,GPR161,CHRM3,PTCH2,B9D1,FGFR4,GPR176,UNC5C,IL17RD,CRIM1,VLDLR,EFNA3,GRID1,CALCRL,OR11H4,TLR6,LEPR,GPR19,GPR37,PTPRC,GRIK4,OR2T33,ADGRB3,PTPRN2,GRIN2D,IL9R GO:0099516 ion antiporter activity 0.586882430021604 -0.532930768786049 63 6 0.00357142857142857 1680 17224 6520,54020,23657,285335,150159,84679 SLC3A2,SLC37A1,SLC7A11,SLC9C1,SLC9B1,SLC9A7 GO:0003735 structural constituent of ribosome 0.593802595346115 -0.521208345920845 159 15 0.00892857142857143 1680 17224 6224,6154,51187,6136,6158,6205,6144,29093,6124,6206,51121,23521,6228,6207,6164 RPS20,RPL26,RSL24D1,RPL12,RPL28,RPS11,RPL21,MRPL22,RPL4,RPS12,RPL26L1,RPL13A,RPS23,RPS13,RPL34 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen 0.594000974168789 -0.52087431960604 31 3 0.00178571428571429 1680 17224 113612,1573,1545 CYP2U1,CYP2J2,CYP1B1 GO:0097718 disordered domain specific binding 0.594000974168789 -0.52087431960604 31 3 0.00178571428571429 1680 17224 2597,2335,3306 GAPDH,FN1,HSPA2 GO:0005343 organic acid:sodium symporter activity 0.594000974168789 -0.52087431960604 31 3 0.00178571428571429 1680 17224 55117,6536,6507 SLC6A15,SLC6A9,SLC1A3 GO:0070006 metalloaminopeptidase activity 0.594184928997628 -0.520564679793249 20 2 0.00119047619047619 1680 17224 4324,4325 MMP15,MMP16 GO:0031683 G-protein beta/gamma-subunit complex binding 0.594184928997628 -0.520564679793249 20 2 0.00119047619047619 1680 17224 2775,2770 GNAO1,GNAI1 GO:0042974 retinoic acid receptor binding 0.594184928997628 -0.520564679793249 20 2 0.00119047619047619 1680 17224 23532,64324 PRAME,NSD1 GO:0016408 C-acyltransferase activity 0.594184928997628 -0.520564679793249 20 2 0.00119047619047619 1680 17224 23464,6296 GCAT,ACSM3 GO:0035257 nuclear hormone receptor binding 0.595075324447951 -0.519067285738226 138 13 0.00773809523809524 1680 17224 4088,23532,64324,10579,5579,3164,135112,2274,23426,6604,6777,5585,10891 SMAD3,PRAME,NSD1,TACC2,PRKCB,NR4A1,NCOA7,FHL2,GRIP1,SMARCD3,STAT5B,PKN1,PPARGC1A GO:0043028 cysteine-type endopeptidase regulator activity involved in apoptotic process 0.596187970485806 -0.517199274919574 42 4 0.00238095238095238 1680 17224 2621,10399,27018,6622 GAS6,RACK1,BEX3,SNCA GO:0042805 actinin binding 0.596187970485806 -0.517199274919574 42 4 0.00238095238095238 1680 17224 9172,171024,3781,23022 MYOM2,SYNPO2,KCNN2,PALLD GO:0015280 ligand-gated sodium channel activity 0.603027158357044 -0.505793044534431 9 1 0.000595238095238095 1680 17224 41 ASIC1 GO:0002162 dystroglycan binding 0.603027158357044 -0.505793044534431 9 1 0.000595238095238095 1680 17224 4133 MAP2 GO:0032393 MHC class I receptor activity 0.603027158357044 -0.505793044534431 9 1 0.000595238095238095 1680 17224 10859 LILRB1 GO:0034713 type I transforming growth factor beta receptor binding 0.603027158357044 -0.505793044534431 9 1 0.000595238095238095 1680 17224 4091 SMAD6 GO:1901612 cardiolipin binding 0.603027158357044 -0.505793044534431 9 1 0.000595238095238095 1680 17224 1687 GSDME GO:0000990 transcription factor activity, core RNA polymerase binding 0.603027158357044 -0.505793044534431 9 1 0.000595238095238095 1680 17224 2963 GTF2F2 GO:0032794 GTPase activating protein binding 0.603027158357044 -0.505793044534431 9 1 0.000595238095238095 1680 17224 2770 GNAI1 GO:0003964 RNA-directed DNA polymerase activity 0.603027158357044 -0.505793044534431 9 1 0.000595238095238095 1680 17224 7015 TERT GO:0033130 acetylcholine receptor binding 0.603027158357044 -0.505793044534431 9 1 0.000595238095238095 1680 17224 9378 NRXN1 GO:0032036 myosin heavy chain binding 0.603027158357044 -0.505793044534431 9 1 0.000595238095238095 1680 17224 270 AMPD1 GO:0015379 potassium:chloride symporter activity 0.603027158357044 -0.505793044534431 9 1 0.000595238095238095 1680 17224 9990 SLC12A6 GO:0003720 telomerase activity 0.603027158357044 -0.505793044534431 9 1 0.000595238095238095 1680 17224 7015 TERT GO:0047498 calcium-dependent phospholipase A2 activity 0.603027158357044 -0.505793044534431 9 1 0.000595238095238095 1680 17224 5321 PLA2G4A GO:0015166 polyol transmembrane transporter activity 0.603027158357044 -0.505793044534431 9 1 0.000595238095238095 1680 17224 114134 SLC2A13 GO:0046703 natural killer cell lectin-like receptor binding 0.603027158357044 -0.505793044534431 9 1 0.000595238095238095 1680 17224 80329 ULBP1 GO:0071933 Arp2/3 complex binding 0.603027158357044 -0.505793044534431 9 1 0.000595238095238095 1680 17224 51429 SNX9 GO:0016624 oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor 0.603027158357044 -0.505793044534431 9 1 0.000595238095238095 1680 17224 55753 OGDHL GO:0031404 chloride ion binding 0.603027158357044 -0.505793044534431 9 1 0.000595238095238095 1680 17224 57502 NLGN4X GO:0019869 chloride channel inhibitor activity 0.603027158357044 -0.505793044534431 9 1 0.000595238095238095 1680 17224 8673 VAMP8 GO:0017151 DEAD/H-box RNA helicase binding 0.603027158357044 -0.505793044534431 9 1 0.000595238095238095 1680 17224 4088 SMAD3 GO:0015377 cation:chloride symporter activity 0.603027158357044 -0.505793044534431 9 1 0.000595238095238095 1680 17224 9990 SLC12A6 GO:0008525 phosphatidylcholine transporter activity 0.603027158357044 -0.505793044534431 9 1 0.000595238095238095 1680 17224 5360 PLTP GO:0052659 inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity 0.603027158357044 -0.505793044534431 9 1 0.000595238095238095 1680 17224 3636 INPPL1 GO:0070567 cytidylyltransferase activity 0.603027158357044 -0.505793044534431 9 1 0.000595238095238095 1680 17224 1040 CDS1 GO:0015036 disulfide oxidoreductase activity 0.615193496612199 -0.485818432023107 43 4 0.00238095238095238 1680 17224 9446,119391,56605,114112 GSTO1,GSTO2,ERO1B,TXNRD3 GO:0005326 neurotransmitter transporter activity 0.616190905439995 -0.484198452032681 54 5 0.00297619047619048 1680 17224 55117,6536,6507,23657,206358 SLC6A15,SLC6A9,SLC1A3,SLC7A11,SLC36A1 GO:0046961 proton-transporting ATPase activity, rotational mechanism 0.621273503272607 -0.47598387005737 21 2 0.00119047619047619 1680 17224 90423,92270 ATP6V1E2,ATP6AP1L GO:0001965 G-protein alpha-subunit binding 0.621273503272607 -0.47598387005737 21 2 0.00119047619047619 1680 17224 29899,6001 GPSM2,RGS10 GO:0004198 calcium-dependent cysteine-type endopeptidase activity 0.621273503272607 -0.47598387005737 21 2 0.00119047619047619 1680 17224 25801,726 GCA,CAPN5 GO:0001046 core promoter sequence-specific DNA binding 0.62301758664763 -0.473180531624205 87 8 0.00476190476190476 1680 17224 1051,54937,2625,148523,468,26508,4208,7020 CEBPB,SOHLH2,GATA3,CIART,ATF4,HEYL,MEF2C,TFAP2A GO:0008227 G-protein coupled amine receptor activity 0.632709760826896 -0.457743475689098 55 5 0.00297619047619048 1680 17224 3363,51222,390442,1131,153 HTR7,ZNF219,OR11H4,CHRM3,ADRB1 GO:0048306 calcium-dependent protein binding 0.632709760826896 -0.457743475689098 55 5 0.00297619047619048 1680 17224 4642,6616,5881,7466,7436 MYO1D,SNAP25,RAC3,WFS1,VLDLR GO:0043621 protein self-association 0.632709760826896 -0.457743475689098 55 5 0.00297619047619048 1680 17224 6262,92,3397,29899,79188 RYR2,ACVR2A,ID1,GPSM2,TMEM43 GO:0001105 RNA polymerase II transcription coactivator activity 0.633631406744278 -0.456287870985223 44 4 0.00238095238095238 1680 17224 4869,23414,116931,473 NPM1,ZFPM2,MED12L,RERE GO:0060590 ATPase regulator activity 0.633631406744278 -0.456287870985223 44 4 0.00238095238095238 1680 17224 9531,93974,481,134266 BAG3,ATP5IF1,ATP1B1,GRPEL2 GO:0015924 mannosyl-oligosaccharide mannosidase activity 0.6417674647104 -0.443529245405005 10 1 0.000595238095238095 1680 17224 80267 EDEM3 GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding 0.6417674647104 -0.443529245405005 10 1 0.000595238095238095 1680 17224 64754 SMYD3 GO:0016892 endoribonuclease activity, producing 3'-phosphomonoesters 0.6417674647104 -0.443529245405005 10 1 0.000595238095238095 1680 17224 10247 RIDA GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor 0.6417674647104 -0.443529245405005 10 1 0.000595238095238095 1680 17224 440 ASNS GO:0140078 class I DNA-(apurinic or apyrimidinic site) endonuclease activity 0.6417674647104 -0.443529245405005 10 1 0.000595238095238095 1680 17224 200558 APLF GO:0008821 crossover junction endodeoxyribonuclease activity 0.6417674647104 -0.443529245405005 10 1 0.000595238095238095 1680 17224 79008 SLX1B GO:0016176 superoxide-generating NADPH oxidase activator activity 0.6417674647104 -0.443529245405005 10 1 0.000595238095238095 1680 17224 285590 SH3PXD2B GO:0071723 lipopeptide binding 0.6417674647104 -0.443529245405005 10 1 0.000595238095238095 1680 17224 10333 TLR6 GO:0008474 palmitoyl-(protein) hydrolase activity 0.6417674647104 -0.443529245405005 10 1 0.000595238095238095 1680 17224 84945 ABHD13 GO:0017128 phospholipid scramblase activity 0.6417674647104 -0.443529245405005 10 1 0.000595238095238095 1680 17224 57088 PLSCR4 GO:0019966 interleukin-1 binding 0.6417674647104 -0.443529245405005 10 1 0.000595238095238095 1680 17224 10626 TRIM16 GO:0098599 palmitoyl hydrolase activity 0.6417674647104 -0.443529245405005 10 1 0.000595238095238095 1680 17224 84945 ABHD13 GO:0003680 AT DNA binding 0.6417674647104 -0.443529245405005 10 1 0.000595238095238095 1680 17224 4208 MEF2C GO:0015467 G-protein activated inward rectifier potassium channel activity 0.6417674647104 -0.443529245405005 10 1 0.000595238095238095 1680 17224 3761 KCNJ4 GO:0004955 prostaglandin receptor activity 0.6417674647104 -0.443529245405005 10 1 0.000595238095238095 1680 17224 3248 HPGD GO:0051864 histone demethylase activity (H3-K36 specific) 0.6417674647104 -0.443529245405005 10 1 0.000595238095238095 1680 17224 80853 KDM7A GO:0008296 3'-5'-exodeoxyribonuclease activity 0.6417674647104 -0.443529245405005 10 1 0.000595238095238095 1680 17224 3669 ISG20 GO:0019911 structural constituent of myelin sheath 0.6417674647104 -0.443529245405005 10 1 0.000595238095238095 1680 17224 152189 CMTM8 GO:0031957 very long-chain fatty acid-CoA ligase activity 0.6417674647104 -0.443529245405005 10 1 0.000595238095238095 1680 17224 11001 SLC27A2 GO:0061608 nuclear import signal receptor activity 0.6417674647104 -0.443529245405005 10 1 0.000595238095238095 1680 17224 3839 KPNA3 GO:0016595 glutamate binding 0.6417674647104 -0.443529245405005 10 1 0.000595238095238095 1680 17224 6507 SLC1A3 GO:0004875 complement receptor activity 0.6417674647104 -0.443529245405005 10 1 0.000595238095238095 1680 17224 1380 CR2 GO:0017153 sodium:dicarboxylate symporter activity 0.6417674647104 -0.443529245405005 10 1 0.000595238095238095 1680 17224 6507 SLC1A3 GO:0019865 immunoglobulin binding 0.646942143737527 -0.43549841083278 22 2 0.00119047619047619 1680 17224 3512,3958 JCHAIN,LGALS3 GO:0001871 pattern binding 0.646942143737527 -0.43549841083278 22 2 0.00119047619047619 1680 17224 5167,178 ENPP1,AGL GO:0005112 Notch binding 0.646942143737527 -0.43549841083278 22 2 0.00119047619047619 1680 17224 79094,92737 CHAC1,DNER GO:0099589 serotonin receptor activity 0.646942143737527 -0.43549841083278 22 2 0.00119047619047619 1680 17224 3363,390442 HTR7,OR11H4 GO:0030247 polysaccharide binding 0.646942143737527 -0.43549841083278 22 2 0.00119047619047619 1680 17224 5167,178 ENPP1,AGL GO:0070034 telomerase RNA binding 0.646942143737527 -0.43549841083278 22 2 0.00119047619047619 1680 17224 55651,7015 NHP2,TERT GO:0004993 G-protein coupled serotonin receptor activity 0.646942143737527 -0.43549841083278 22 2 0.00119047619047619 1680 17224 3363,390442 HTR7,OR11H4 GO:0008028 monocarboxylic acid transmembrane transporter activity 0.648786242679046 -0.432651980661225 56 5 0.00297619047619048 1680 17224 220963,11001,6567,84879,117247 SLC16A9,SLC27A2,SLC16A2,MFSD2A,SLC16A10 GO:0000049 tRNA binding 0.648786242679046 -0.432651980661225 56 5 0.00297619047619048 1680 17224 833,4141,7015,16,221078 CARS,MARS,TERT,AARS,NSUN6 GO:0016830 carbon-carbon lyase activity 0.648786242679046 -0.432651980661225 56 5 0.00297619047619048 1680 17224 5106,171425,230,4597,226 PCK2,CLYBL,ALDOC,MVD,ALDOA GO:0042826 histone deacetylase binding 0.650091028751664 -0.430642881664404 100 9 0.00535714285714286 1680 17224 56271,1051,5071,138151,51339,100271849,639,5585,4208 BEX4,CEBPB,PRKN,NACC2,DACT1,MEF2B,PRDM1,PKN1,MEF2C GO:0004601 peroxidase activity 0.651488103097441 -0.428496143370705 45 4 0.00238095238095238 1680 17224 2946,26034,241,4259 GSTM2,IPCEF1,ALOX5AP,MGST3 GO:0015020 glucuronosyltransferase activity 0.657578617983369 -0.419190951000902 34 3 0.00178571428571429 1680 17224 337876,22856,7368 CHSY3,CHSY1,UGT8 GO:0008536 Ran GTPase binding 0.657578617983369 -0.419190951000902 34 3 0.00178571428571429 1680 17224 5903,26297,3843 RANBP2,SERGEF,IPO5 GO:0000989 transcription factor activity, transcription factor binding 0.661657859288653 -0.413006685516307 209 19 0.0113095238095238 1680 17224 3397,468,4779,10413,4869,23414,256536,473,57491,4088,3399,8320,138151,26508,9443,10891,116931,23462,83666 ID1,ATF4,NFE2L1,YAP1,NPM1,ZFPM2,TCERG1L,RERE,AHRR,SMAD3,ID3,EOMES,NACC2,HEYL,MED7,PPARGC1A,MED12L,HEY1,PARP9 GO:0001076 transcription factor activity, RNA polymerase II transcription factor binding 0.665560052321783 -0.407126408821662 188 17 0.0101190476190476 1680 17224 3397,468,4779,10413,4869,23414,256536,473,57491,3399,8320,138151,26508,9443,10891,116931,83666 ID1,ATF4,NFE2L1,YAP1,NPM1,ZFPM2,TCERG1L,RERE,AHRR,ID3,EOMES,NACC2,HEYL,MED7,PPARGC1A,MED12L,PARP9 GO:0004622 lysophospholipase activity 0.671209973654332 -0.398673264502217 23 2 0.00119047619047619 1680 17224 5321,284161 PLA2G4A,GDPD1 GO:0016894 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters 0.671209973654332 -0.398673264502217 23 2 0.00119047619047619 1680 17224 10247,79008 RIDA,SLX1B GO:0070840 dynein complex binding 0.671209973654332 -0.398673264502217 23 2 0.00119047619047619 1680 17224 29899,6622 GPSM2,SNCA GO:0008187 poly-pyrimidine tract binding 0.671209973654332 -0.398673264502217 23 2 0.00119047619047619 1680 17224 54033,202559 RBM11,KHDRBS2 GO:0008568 microtubule-severing ATPase activity 0.676729162140933 -0.390484142035393 11 1 0.000595238095238095 1680 17224 55137 FIGN GO:0008503 benzodiazepine receptor activity 0.676729162140933 -0.390484142035393 11 1 0.000595238095238095 1680 17224 2566 GABRG2 GO:0004000 adenosine deaminase activity 0.676729162140933 -0.390484142035393 11 1 0.000595238095238095 1680 17224 161823 ADAL GO:0016868 intramolecular transferase activity, phosphotransferases 0.676729162140933 -0.390484142035393 11 1 0.000595238095238095 1680 17224 283209 PGM2L1 GO:0032052 bile acid binding 0.676729162140933 -0.390484142035393 11 1 0.000595238095238095 1680 17224 2172 FABP6 GO:0098748 endocytic adaptor activity 0.676729162140933 -0.390484142035393 11 1 0.000595238095238095 1680 17224 3092 HIP1 GO:0047429 nucleoside-triphosphate diphosphatase activity 0.676729162140933 -0.390484142035393 11 1 0.000595238095238095 1680 17224 5167 ENPP1 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines 0.676729162140933 -0.390484142035393 11 1 0.000595238095238095 1680 17224 23576 DDAH1 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity 0.676729162140933 -0.390484142035393 11 1 0.000595238095238095 1680 17224 9846 GAB2 GO:0016888 endodeoxyribonuclease activity, producing 5'-phosphomonoesters 0.676729162140933 -0.390484142035393 11 1 0.000595238095238095 1680 17224 79008 SLX1B GO:0051378 serotonin binding 0.676729162140933 -0.390484142035393 11 1 0.000595238095238095 1680 17224 3363 HTR7 GO:0043023 ribosomal large subunit binding 0.676729162140933 -0.390484142035393 11 1 0.000595238095238095 1680 17224 4869 NPM1 GO:0019211 phosphatase activator activity 0.676729162140933 -0.390484142035393 11 1 0.000595238095238095 1680 17224 3486 IGFBP3 GO:0070411 I-SMAD binding 0.676729162140933 -0.390484142035393 11 1 0.000595238095238095 1680 17224 4091 SMAD6 GO:0043176 amine binding 0.676729162140933 -0.390484142035393 11 1 0.000595238095238095 1680 17224 3363 HTR7 GO:0050072 m7G(5')pppN diphosphatase activity 0.676729162140933 -0.390484142035393 11 1 0.000595238095238095 1680 17224 170685 NUDT10 GO:0004954 prostanoid receptor activity 0.676729162140933 -0.390484142035393 11 1 0.000595238095238095 1680 17224 3248 HPGD GO:0052743 inositol tetrakisphosphate phosphatase activity 0.676729162140933 -0.390484142035393 11 1 0.000595238095238095 1680 17224 3636 INPPL1 GO:0016803 ether hydrolase activity 0.676729162140933 -0.390484142035393 11 1 0.000595238095238095 1680 17224 144110 TMEM86A GO:0048407 platelet-derived growth factor binding 0.676729162140933 -0.390484142035393 11 1 0.000595238095238095 1680 17224 5159 PDGFRB GO:0089720 caspase binding 0.676729162140933 -0.390484142035393 11 1 0.000595238095238095 1680 17224 4102 MAGEA3 GO:0008970 phosphatidylcholine 1-acylhydrolase activity 0.676729162140933 -0.390484142035393 11 1 0.000595238095238095 1680 17224 5321 PLA2G4A GO:0035615 clathrin adaptor activity 0.676729162140933 -0.390484142035393 11 1 0.000595238095238095 1680 17224 3092 HIP1 GO:0050811 GABA receptor binding 0.676729162140933 -0.390484142035393 11 1 0.000595238095238095 1680 17224 23710 GABARAPL1 GO:0004791 thioredoxin-disulfide reductase activity 0.676729162140933 -0.390484142035393 11 1 0.000595238095238095 1680 17224 114112 TXNRD3 GO:0015643 toxic substance binding 0.676729162140933 -0.390484142035393 11 1 0.000595238095238095 1680 17224 445 ASS1 GO:0004842 ubiquitin-protein transferase activity 0.691671804417356 -0.36864370693975 448 41 0.0244047619047619 1680 17224 91694,5071,23321,9781,90293,26272,57520,51191,11237,55008,9920,26262,4734,143279,50862,285671,114907,8139,10612,64219,9443,25827,114818,220441,153830,151230,26249,56062,54941,22838,114088,60468,154214,57161,55819,126433,401265,79845,143384,8945,57531 LONRF1,PRKN,TRIM2,RNF144A,KLHL13,FBXO4,HECW2,HERC5,RNF24,HERC6,KBTBD11,TSPAN17,NEDD4,HECTD2,RNF141,RNF180,FBXO32,GAN,TRIM3,PJA1,MED7,FBXL2,KLHL29,RNF152,RNF145,KLHL23,KLHL3,KLHL4,RNF125,RNF44,TRIM9,BACH2,RNF217,PELI2,RNF130,FBXO27,KLHL31,RNF122,CACUL1,BTRC,HACE1 GO:0004190 aspartic-type endopeptidase activity 0.694105891635793 -0.365130748506951 24 2 0.00119047619047619 1680 17224 25825,23621 BACE2,BACE1 GO:0005540 hyaluronic acid binding 0.694105891635793 -0.365130748506951 24 2 0.00119047619047619 1680 17224 63827,23670 BCAN,CEMIP2 GO:0003707 steroid hormone receptor activity 0.694271519881863 -0.364892155966505 59 5 0.00297619047619048 1680 17224 3174,2649,4306,3164,2104 HNF4G,NR6A1,NR3C2,NR4A1,ESRRG GO:0005109 frizzled binding 0.695790502582545 -0.362706665994496 36 3 0.00178571428571429 1680 17224 4040,7481,8321 LRP6,WNT11,FZD1 GO:0019239 deaminase activity 0.695790502582545 -0.362706665994496 36 3 0.00178571428571429 1680 17224 10247,161823,270 RIDA,ADAL,AMPD1 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding 0.695790502582545 -0.362706665994496 36 3 0.00178571428571429 1680 17224 1051,26508,7020 CEBPB,HEYL,TFAP2A GO:0051087 chaperone binding 0.697310265862791 -0.36052482255924 93 8 0.00476190476190476 1680 17224 9531,5071,2335,7015,5611,3306,134266,478 BAG3,PRKN,FN1,TERT,DNAJC3,HSPA2,GRPEL2,ATP1A3 GO:0048018 receptor ligand activity 0.701072313910985 -0.355144239049752 471 43 0.0255952380952381 1680 17224 685,4681,9235,3958,2258,3600,152189,10673,50810,2621,10584,654,53342,2202,1890,10505,23767,8614,7424,627,2660,79924,8838,7039,2257,8822,22943,3626,3627,10718,2200,1435,100506013,7060,83729,649,10512,9966,3082,652,7292,10371,114336 BTC,NBL1,IL32,LGALS3,FGF13,IL15,CMTM8,TNFSF13B,HDGFL3,GAS6,COLEC10,BMP6,IL17D,EFEMP1,TYMP,SEMA4F,FLRT3,STC2,VEGFC,BDNF,MSTN,ADM2,WISP3,TGFA,FGF12,FGF17,DKK1,INHBC,CXCL10,NRG3,FBN1,CSF1,APELA,THBS4,INHBE,BMP1,SEMA3C,TNFSF15,HGF,BMP4,TNFSF4,SEMA3A,CGB2 GO:0001102 RNA polymerase II activating transcription factor binding 0.701489199409231 -0.354549775981197 48 4 0.00238095238095238 1680 17224 100271849,4088,8320,4208 MEF2B,SMAD3,EOMES,MEF2C GO:0016783 sulfurtransferase activity 0.708280606244303 -0.34491492730573 12 1 0.000595238095238095 1680 17224 55034 MOCOS GO:0086008 voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization 0.708280606244303 -0.34491492730573 12 1 0.000595238095238095 1680 17224 3752 KCND3 GO:0002161 aminoacyl-tRNA editing activity 0.708280606244303 -0.34491492730573 12 1 0.000595238095238095 1680 17224 16 AARS GO:0106019 phosphatidylinositol-4,5-bisphosphate phosphatase activity 0.708280606244303 -0.34491492730573 12 1 0.000595238095238095 1680 17224 8821 INPP4B GO:0008253 5'-nucleotidase activity 0.708280606244303 -0.34491492730573 12 1 0.000595238095238095 1680 17224 64943 NT5DC2 GO:0015296 anion:cation symporter activity 0.708280606244303 -0.34491492730573 12 1 0.000595238095238095 1680 17224 9990 SLC12A6 GO:0015368 calcium:cation antiporter activity 0.708280606244303 -0.34491492730573 12 1 0.000595238095238095 1680 17224 6520 SLC3A2 GO:0022851 GABA-gated chloride ion channel activity 0.708280606244303 -0.34491492730573 12 1 0.000595238095238095 1680 17224 2566 GABRG2 GO:0046965 retinoid X receptor binding 0.708280606244303 -0.34491492730573 12 1 0.000595238095238095 1680 17224 64324 NSD1 GO:0019855 calcium channel inhibitor activity 0.708280606244303 -0.34491492730573 12 1 0.000595238095238095 1680 17224 29763 PACSIN3 GO:0005542 folic acid binding 0.708280606244303 -0.34491492730573 12 1 0.000595238095238095 1680 17224 348751 FTCDNL1 GO:0008235 metalloexopeptidase activity 0.708499560385617 -0.344605840337668 60 5 0.00297619047619048 1680 17224 4324,119587,1363,4325,254042 MMP15,CPXM2,CPE,MMP16,METAP1D GO:0019843 rRNA binding 0.708499560385617 -0.344605840337668 60 5 0.00297619047619048 1680 17224 6136,1938,29997,6205,6207 RPL12,EEF2,NOP53,RPS11,RPS13 GO:0038023 signaling receptor activity 0.714764671880326 -0.335801920700679 1432 134 0.0797619047619048 1680 17224 90,55366,2898,10859,92737,2152,7049,3690,2051,343171,5791,7099,7253,3556,5159,3695,130399,1630,2649,1380,93,4919,26512,10082,25987,285601,51704,153,7132,5021,166647,8829,219699,23266,81491,7301,9902,9620,5789,2561,8794,924,55504,8809,57211,2202,3480,23596,4040,23554,2674,23432,1131,8643,2264,11245,8633,54756,7436,1944,10203,390442,2842,2900,577,5799,2042,643,6785,1951,8477,5362,4916,3597,79339,9378,780,2838,7098,51310,1138,22859,92,4233,8321,118429,8322,10076,27133,5777,8973,958,2260,3363,26996,5754,3673,84451,3248,657,4306,3977,282763,9170,60401,6092,659,8325,4038,2566,2570,5028,51222,2047,576,4756,2690,8792,27077,51232,3174,2104,3164,2894,10333,3953,5788,2861,391195,4163,2906,6510,608,3581 ACVR1,LGR4,GRIK2,LILRB1,DNER,F3,TGFBR3,ITGB3,EPHB6,OR2W3,PTPRE,TLR4,TSHR,IL1RAP,PDGFRB,ITGB7,ACVR1C,DCC,NR6A1,CR2,ACVR2B,ROR1,INTS6,GPC6,TSKU,GPR150,GPRC5B,ADRB1,TNFRSF1A,OXTR,ADGRA3,NRP1,UNC5B,ADGRL2,GPR63,TYRO3,MRC2,CELSR1,PTPRD,GABRB2,TNFRSF10C,CD7,TNFRSF19,IL18R1,ADGRG6,EFEMP1,IGF1R,OPN3,LRP6,TSPAN12,GFRA1,GPR161,CHRM3,PTCH2,FGFR4,GPR176,UNC5C,IL17RD,VLDLR,EFNA3,CALCRL,OR11H4,GPR19,GRIK4,ADGRB3,PTPRN2,EPHA3,CXCR5,ELOVL4,CELSR3,GPR65,PLXNA2,NTRK3,IL13RA1,OR51B4,NRXN1,DDR1,GPR15,TLR3,SLC22A17,CHRNA5,ADGRL1,ACVR2A,MET,FZD1,ANTXR2,FZD4,PTPRU,KCNH5,PTPN6,CHRNA6,CD40,FGFR1,HTR7,GPR160,PTK7,ITGA2,MAP3K21,HPGD,BMPR1A,NR3C2,LIFR,OR51B5,LPAR2,EDA2R,ROBO2,BMPR2,FZD8,LRP4,GABRG2,GABRR2,P2RY1,ZNF219,EPHB1,ADGRB2,NEO1,GHR,TNFRSF11A,B9D1,CRIM1,HNF4G,ESRRG,NR4A1,GRID1,TLR6,LEPR,PTPRC,GPR37,OR2T33,MCC,GRIN2D,SLC1A5,TNFRSF17,IL9R GO:0060089 molecular transducer activity 0.714764671880326 -0.335801920700679 1432 134 0.0797619047619048 1680 17224 90,55366,2898,10859,92737,2152,7049,3690,2051,5791,343171,7099,7253,3556,5159,3695,130399,1630,2649,1380,93,4919,26512,10082,25987,285601,51704,153,7132,5021,166647,8829,219699,23266,81491,7301,9902,9620,5789,2561,8794,924,55504,8809,57211,2202,3480,23596,4040,23554,2674,23432,1131,8643,2264,11245,8633,54756,7436,1944,10203,390442,2842,2900,577,5799,2042,643,6785,1951,8477,5362,4916,3597,79339,9378,780,2838,7098,51310,1138,22859,92,4233,8321,118429,8322,10076,27133,5777,8973,958,2260,3363,26996,5754,3673,84451,3248,657,4306,3977,282763,9170,60401,6092,659,8325,4038,2566,2570,5028,51222,2047,576,4756,2690,8792,27077,51232,3174,2104,3164,2894,10333,3953,5788,2861,391195,4163,2906,6510,608,3581 ACVR1,LGR4,GRIK2,LILRB1,DNER,F3,TGFBR3,ITGB3,EPHB6,PTPRE,OR2W3,TLR4,TSHR,IL1RAP,PDGFRB,ITGB7,ACVR1C,DCC,NR6A1,CR2,ACVR2B,ROR1,INTS6,GPC6,TSKU,GPR150,GPRC5B,ADRB1,TNFRSF1A,OXTR,ADGRA3,NRP1,UNC5B,ADGRL2,GPR63,TYRO3,MRC2,CELSR1,PTPRD,GABRB2,TNFRSF10C,CD7,TNFRSF19,IL18R1,ADGRG6,EFEMP1,IGF1R,OPN3,LRP6,TSPAN12,GFRA1,GPR161,CHRM3,PTCH2,FGFR4,GPR176,UNC5C,IL17RD,VLDLR,EFNA3,CALCRL,OR11H4,GPR19,GRIK4,ADGRB3,PTPRN2,EPHA3,CXCR5,ELOVL4,CELSR3,GPR65,PLXNA2,NTRK3,IL13RA1,OR51B4,NRXN1,DDR1,GPR15,TLR3,SLC22A17,CHRNA5,ADGRL1,ACVR2A,MET,FZD1,ANTXR2,FZD4,PTPRU,KCNH5,PTPN6,CHRNA6,CD40,FGFR1,HTR7,GPR160,PTK7,ITGA2,MAP3K21,HPGD,BMPR1A,NR3C2,LIFR,OR51B5,LPAR2,EDA2R,ROBO2,BMPR2,FZD8,LRP4,GABRG2,GABRR2,P2RY1,ZNF219,EPHB1,ADGRB2,NEO1,GHR,TNFRSF11A,B9D1,CRIM1,HNF4G,ESRRG,NR4A1,GRID1,TLR6,LEPR,PTPRC,GPR37,OR2T33,MCC,GRIN2D,SLC1A5,TNFRSF17,IL9R GO:0005126 cytokine receptor binding 0.715061059472722 -0.335387342070372 270 24 0.0142857142857143 1680 17224 7424,627,3600,2660,10673,65997,2625,10464,654,4088,3626,3627,7049,1896,27018,1435,3690,83729,9966,153090,652,7292,4091,3977 VEGFC,BDNF,IL15,MSTN,TNFSF13B,RASL11B,GATA3,PIBF1,BMP6,SMAD3,INHBC,CXCL10,TGFBR3,EDA,BEX3,CSF1,ITGB3,INHBE,TNFSF15,DAB2IP,BMP4,TNFSF4,SMAD6,LIFR GO:0070001 aspartic-type peptidase activity 0.715666484449557 -0.334541024383202 25 2 0.00119047619047619 1680 17224 25825,23621 BACE2,BACE1 GO:0015035 protein disulfide oxidoreductase activity 0.715666484449557 -0.334541024383202 25 2 0.00119047619047619 1680 17224 56605,114112 ERO1B,TXNRD3 GO:0001972 retinoic acid binding 0.715666484449557 -0.334541024383202 25 2 0.00119047619047619 1680 17224 9227,1592 LRAT,CYP26A1 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process 0.715666484449557 -0.334541024383202 25 2 0.00119047619047619 1680 17224 2621,6622 GAS6,SNCA GO:1901567 fatty acid derivative binding 0.715666484449557 -0.334541024383202 25 2 0.00119047619047619 1680 17224 241,8435 ALOX5AP,SOAT2 GO:0015294 solute:cation symporter activity 0.717414464150958 -0.33210155218177 106 9 0.00535714285714286 1680 17224 6536,206358,11182,55117,154091,6507,9990,114134,85414 SLC6A9,SLC36A1,SLC2A6,SLC6A15,SLC2A12,SLC1A3,SLC12A6,SLC2A13,SLC45A3 GO:0005506 iron ion binding 0.722608661376249 -0.32488747393544 151 13 0.00773809523809524 1680 17224 1595,80853,5352,6307,1573,8974,285440,5033,6319,113612,1592,1545,6622 CYP51A1,KDM7A,PLOD2,MSMO1,CYP2J2,P4HA2,CYP4V2,P4HA1,SCD,CYP2U1,CYP26A1,CYP1B1,SNCA GO:0005484 SNAP receptor activity 0.730681311655595 -0.313777876458942 38 3 0.00178571428571429 1680 17224 6616,662,8673 SNAP25,BNIP1,VAMP8 GO:0004435 phosphatidylinositol phospholipase C activity 0.735934254477687 -0.306614492398575 26 2 0.00119047619047619 1680 17224 23236,1131 PLCB1,CHRM3 GO:0071855 neuropeptide receptor binding 0.735934254477687 -0.306614492398575 26 2 0.00119047619047619 1680 17224 2775,100506013 GNAO1,APELA GO:0042605 peptide antigen binding 0.735934254477687 -0.306614492398575 26 2 0.00119047619047619 1680 17224 1718,8140 DHCR24,SLC7A5 GO:0005104 fibroblast growth factor receptor binding 0.735934254477687 -0.306614492398575 26 2 0.00119047619047619 1680 17224 8822,23767 FGF17,FLRT3 GO:0001968 fibronectin binding 0.735934254477687 -0.306614492398575 26 2 0.00119047619047619 1680 17224 3690,3486 ITGB3,IGFBP3 GO:0017091 AU-rich element binding 0.735934254477687 -0.306614492398575 26 2 0.00119047619047619 1680 17224 678,64506 ZFP36L2,CPEB1 GO:0034450 ubiquitin-ubiquitin ligase activity 0.736754263091036 -0.305500871034232 13 1 0.000595238095238095 1680 17224 57161 PELI2 GO:0003906 DNA-(apurinic or apyrimidinic site) endonuclease activity 0.736754263091036 -0.305500871034232 13 1 0.000595238095238095 1680 17224 200558 APLF GO:0035497 cAMP response element binding 0.736754263091036 -0.305500871034232 13 1 0.000595238095238095 1680 17224 64764 CREB3L2 GO:0008242 omega peptidase activity 0.736754263091036 -0.305500871034232 13 1 0.000595238095238095 1680 17224 23621 BACE1 GO:0008417 fucosyltransferase activity 0.736754263091036 -0.305500871034232 13 1 0.000595238095238095 1680 17224 10690 FUT9 GO:0008553 proton-exporting ATPase activity, phosphorylative mechanism 0.736754263091036 -0.305500871034232 13 1 0.000595238095238095 1680 17224 90423 ATP6V1E2 GO:0016775 phosphotransferase activity, nitrogenous group as acceptor 0.736754263091036 -0.305500871034232 13 1 0.000595238095238095 1680 17224 27133 KCNH5 GO:0016889 endodeoxyribonuclease activity, producing 3'-phosphomonoesters 0.736754263091036 -0.305500871034232 13 1 0.000595238095238095 1680 17224 79008 SLX1B GO:0004859 phospholipase inhibitor activity 0.736754263091036 -0.305500871034232 13 1 0.000595238095238095 1680 17224 6622 SNCA GO:0031402 sodium ion binding 0.736754263091036 -0.305500871034232 13 1 0.000595238095238095 1680 17224 481 ATP1B1 GO:0050321 tau-protein kinase activity 0.736754263091036 -0.305500871034232 13 1 0.000595238095238095 1680 17224 4139 MARK1 GO:0051427 hormone receptor binding 0.738933841266003 -0.302546886715387 164 14 0.00833333333333333 1680 17224 4088,23532,64324,10579,5579,3164,2775,135112,2274,23426,6604,6777,5585,10891 SMAD3,PRAME,NSD1,TACC2,PRKCB,NR4A1,GNAO1,NCOA7,FHL2,GRIP1,SMARCD3,STAT5B,PKN1,PPARGC1A GO:0000980 RNA polymerase II distal enhancer sequence-specific DNA binding 0.740431340616621 -0.300522369874736 74 6 0.00357142857142857 1680 17224 9242,60468,2624,5966,4208,4779 MSC,BACH2,GATA2,REL,MEF2C,NFE2L1 GO:0017112 Rab guanyl-nucleotide exchange factor activity 0.74609515778951 -0.292902129554532 51 4 0.00238095238095238 1680 17224 54453,79958,22898,160518 RIN2,DENND1C,DENND3,DENND5B GO:0051059 NF-kappaB binding 0.754956118765297 -0.28109565226286 27 2 0.00119047619047619 1680 17224 4869,6875 NPM1,TAF4B GO:0043015 gamma-tubulin binding 0.754956118765297 -0.28109565226286 27 2 0.00119047619047619 1680 17224 26056,9638 RAB11FIP5,FEZ1 GO:0034593 phosphatidylinositol bisphosphate phosphatase activity 0.754956118765297 -0.28109565226286 27 2 0.00119047619047619 1680 17224 9896,8821 FIG4,INPP4B GO:0043425 bHLH transcription factor binding 0.754956118765297 -0.28109565226286 27 2 0.00119047619047619 1680 17224 4088,860 SMAD3,RUNX2 GO:0004222 metalloendopeptidase activity 0.757271732438012 -0.278033130327789 110 9 0.00535714285714286 1680 17224 170691,4324,89782,9508,649,11174,4325,4311,7093 ADAMTS17,MMP15,LMLN,ADAMTS3,BMP1,ADAMTS6,MMP16,MME,TLL2 GO:0001190 transcriptional activator activity, RNA polymerase II transcription factor binding 0.760705555623527 -0.273508913701322 64 5 0.00297619047619048 1680 17224 4869,23414,116931,473,4779 NPM1,ZFPM2,MED12L,RERE,NFE2L1 GO:0016877 ligase activity, forming carbon-sulfur bonds 0.762342257653538 -0.271359667110673 40 3 0.00178571428571429 1680 17224 2180,11001,6296 ACSL1,SLC27A2,ACSM3 GO:0016801 hydrolase activity, acting on ether bonds 0.762450203957805 -0.271218078917965 14 1 0.000595238095238095 1680 17224 144110 TMEM86A GO:0001846 opsonin binding 0.762450203957805 -0.271218078917965 14 1 0.000595238095238095 1680 17224 720 C4A GO:0001608 G-protein coupled nucleotide receptor activity 0.762450203957805 -0.271218078917965 14 1 0.000595238095238095 1680 17224 5028 P2RY1 GO:0010181 FMN binding 0.762450203957805 -0.271218078917965 14 1 0.000595238095238095 1680 17224 4846 NOS3 GO:0015926 glucosidase activity 0.762450203957805 -0.271218078917965 14 1 0.000595238095238095 1680 17224 178 AGL GO:0031432 titin binding 0.762450203957805 -0.271218078917965 14 1 0.000595238095238095 1680 17224 84033 OBSCN GO:0005523 tropomyosin binding 0.762450203957805 -0.271218078917965 14 1 0.000595238095238095 1680 17224 29767 TMOD2 GO:0008252 nucleotidase activity 0.762450203957805 -0.271218078917965 14 1 0.000595238095238095 1680 17224 64943 NT5DC2 GO:0015114 phosphate ion transmembrane transporter activity 0.762450203957805 -0.271218078917965 14 1 0.000595238095238095 1680 17224 54020 SLC37A1 GO:0045125 bioactive lipid receptor activity 0.762450203957805 -0.271218078917965 14 1 0.000595238095238095 1680 17224 9170 LPAR2 GO:0032454 histone demethylase activity (H3-K9 specific) 0.762450203957805 -0.271218078917965 14 1 0.000595238095238095 1680 17224 80853 KDM7A GO:0030546 receptor activator activity 0.762450203957805 -0.271218078917965 14 1 0.000595238095238095 1680 17224 10718 NRG3 GO:0017110 nucleoside-diphosphatase activity 0.762450203957805 -0.271218078917965 14 1 0.000595238095238095 1680 17224 953 ENTPD1 GO:0016594 glycine binding 0.762450203957805 -0.271218078917965 14 1 0.000595238095238095 1680 17224 2731 GLDC GO:0070742 C2H2 zinc finger domain binding 0.762450203957805 -0.271218078917965 14 1 0.000595238095238095 1680 17224 2624 GATA2 GO:0043024 ribosomal small subunit binding 0.762450203957805 -0.271218078917965 14 1 0.000595238095238095 1680 17224 4869 NPM1 GO:0045028 G-protein coupled purinergic nucleotide receptor activity 0.762450203957805 -0.271218078917965 14 1 0.000595238095238095 1680 17224 5028 P2RY1 GO:0019787 ubiquitin-like protein transferase activity 0.763962014908743 -0.269237209757466 473 42 0.025 1680 17224 91694,5071,23321,9781,90293,26272,57520,51191,11237,55008,9920,26262,4734,143279,50862,285671,114907,8139,10612,64219,9443,25827,114818,220441,153830,151230,26249,56062,54941,22838,114088,5903,60468,154214,57161,55819,126433,401265,79845,143384,8945,57531 LONRF1,PRKN,TRIM2,RNF144A,KLHL13,FBXO4,HECW2,HERC5,RNF24,HERC6,KBTBD11,TSPAN17,NEDD4,HECTD2,RNF141,RNF180,FBXO32,GAN,TRIM3,PJA1,MED7,FBXL2,KLHL29,RNF152,RNF145,KLHL23,KLHL3,KLHL4,RNF125,RNF44,TRIM9,RANBP2,BACH2,RNF217,PELI2,RNF130,FBXO27,KLHL31,RNF122,CACUL1,BTRC,HACE1 GO:0032182 ubiquitin-like protein binding 0.767034170535565 -0.265223927713416 88 7 0.00416666666666667 1680 17224 4088,5071,7347,92181,4734,337867,199990 SMAD3,PRKN,UCHL3,UBTD2,NEDD4,UBAC2,FAAP20 GO:0004683 calmodulin-dependent protein kinase activity 0.772782144801727 -0.257758100903374 28 2 0.00119047619047619 1680 17224 9261,91807 MAPKAPK2,MYLK3 GO:0004181 metallocarboxypeptidase activity 0.772782144801727 -0.257758100903374 28 2 0.00119047619047619 1680 17224 119587,1363 CPXM2,CPE GO:0036442 proton-exporting ATPase activity 0.772782144801727 -0.257758100903374 28 2 0.00119047619047619 1680 17224 90423,92270 ATP6V1E2,ATP6AP1L GO:0008139 nuclear localization sequence binding 0.772782144801727 -0.257758100903374 28 2 0.00119047619047619 1680 17224 3839,3843 KPNA3,IPO5 GO:0030145 manganese ion binding 0.772884944849277 -0.257625083841175 53 4 0.00238095238095238 1680 17224 2591,2589,5106,11285 GALNT3,GALNT1,PCK2,B4GALT7 GO:0044389 ubiquitin-like protein ligase binding 0.77811242873265 -0.250884255305162 324 28 0.0166666666666667 1680 17224 10188,5071,6331,9099,8322,8325,875,114781,5577,958,51429,23710,6497,4088,1051,2861,57761,7466,5002,55353,2272,23111,10891,4091,4281,143384,5567,83666 TNK2,PRKN,SCN5A,USP2,FZD4,FZD8,CBS,BTBD9,PRKAR2B,CD40,SNX9,GABARAPL1,SKI,SMAD3,CEBPB,GPR37,TRIB3,WFS1,SLC22A18,LAPTM4B,FHIT,SPART,PPARGC1A,SMAD6,MID1,CACUL1,PRKACB,PARP9 GO:0004866 endopeptidase inhibitor activity 0.784781399434474 -0.242350072038267 170 14 0.00833333333333333 1680 17224 27344,2597,1285,1447,51232,8434,720,5274,2621,5627,871,11005,50859,6622 PCSK1N,GAPDH,COL4A3,CSN2,CRIM1,RECK,C4A,SERPINI1,GAS6,PROS1,SERPINH1,SPINK5,SPOCK3,SNCA GO:0106018 phosphatidylinositol-3,5-bisphosphate phosphatase activity 0.785639260153511 -0.241257548453418 15 1 0.000595238095238095 1680 17224 9896 FIG4 GO:0019841 retinol binding 0.785639260153511 -0.241257548453418 15 1 0.000595238095238095 1680 17224 9227 LRAT GO:0052744 phosphatidylinositol monophosphate phosphatase activity 0.785639260153511 -0.241257548453418 15 1 0.000595238095238095 1680 17224 9896 FIG4 GO:0015929 hexosaminidase activity 0.785639260153511 -0.241257548453418 15 1 0.000595238095238095 1680 17224 23670 CEMIP2 GO:0030955 potassium ion binding 0.785639260153511 -0.241257548453418 15 1 0.000595238095238095 1680 17224 481 ATP1B1 GO:0004438 phosphatidylinositol-3-phosphatase activity 0.785639260153511 -0.241257548453418 15 1 0.000595238095238095 1680 17224 9896 FIG4 GO:0008276 protein methyltransferase activity 0.786885491519037 -0.239672541126693 90 7 0.00416666666666667 1680 17224 7468,64324,83852,399818,64754,59336,2122 NSD2,NSD1,SETDB2,EEF1AKMT2,SMYD3,PRDM13,MECOM GO:1904680 peptide transmembrane transporter activity 0.789464490493315 -0.236400423507173 29 2 0.00119047619047619 1680 17224 84976,1015 DISP1,CDH17 GO:0008175 tRNA methyltransferase activity 0.789464490493315 -0.236400423507173 29 2 0.00119047619047619 1680 17224 1787,221078 TRDMT1,NSUN6 GO:0061134 peptidase regulator activity 0.792191136008724 -0.23295258293957 216 18 0.0107142857142857 1680 17224 27344,2597,2335,1285,1447,51232,8434,720,2621,10399,11005,6622,27018,5274,5627,26577,871,50859 PCSK1N,GAPDH,FN1,COL4A3,CSN2,CRIM1,RECK,C4A,GAS6,RACK1,SPINK5,SNCA,BEX3,SERPINI1,PROS1,PCOLCE2,SERPINH1,SPOCK3 GO:0051213 dioxygenase activity 0.796323693925158 -0.227749525137979 91 7 0.00416666666666667 1680 17224 80853,5033,10765,6999,5352,444,8974 KDM7A,P4HA1,KDM5B,TDO2,PLOD2,ASPH,P4HA2 GO:0001104 RNA polymerase II transcription cofactor activity 0.798548771281181 -0.224959234568397 103 8 0.00476190476190476 1680 17224 26508,4869,9443,10891,256536,23414,116931,473 HEYL,NPM1,MED7,PPARGC1A,TCERG1L,ZFPM2,MED12L,RERE GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds 0.798548771281181 -0.224959234568397 103 8 0.00476190476190476 1680 17224 23324,10855,23670,283310,340485,80267,178,57462 MAN2B2,HPSE,CEMIP2,OTOGL,ACER2,EDEM3,AGL,MYORG GO:0003682 chromatin binding 0.802373392931434 -0.220181202241829 536 47 0.0279761904761905 1680 17224 5563,860,122953,5966,322,2625,4869,6777,7546,58495,5585,6304,7227,4825,8320,29841,2624,6720,604,7020,9760,11262,4091,93349,2735,81550,10360,59336,4774,10413,6604,7468,23314,639,474,473,4088,1051,83439,64324,5579,7703,3239,1746,10891,4300,4208 PRKAA2,RUNX2,JDP2,REL,APBB1,GATA3,NPM1,STAT5B,ZIC2,OVOL2,PKN1,SATB1,TRPS1,NKX6-1,EOMES,GRHL1,GATA2,SREBF1,BCL6,TFAP2A,TOX,SP140,SMAD6,SP140L,GLI1,TDRD3,NPM3,PRDM13,NFIA,YAP1,SMARCD3,NSD2,SATB2,PRDM1,ATOH1,RERE,SMAD3,CEBPB,TCF7L1,NSD1,PRKCB,PCGF2,HOXD13,DLX2,PPARGC1A,MLLT3,MEF2C GO:0022841 potassium ion leak channel activity 0.806565870794166 -0.214969709867813 16 1 0.000595238095238095 1680 17224 60598 KCNK15 GO:0016805 dipeptidase activity 0.806565870794166 -0.214969709867813 16 1 0.000595238095238095 1680 17224 9805 SCRN1 GO:0023026 MHC class II protein complex binding 0.806565870794166 -0.214969709867813 16 1 0.000595238095238095 1680 17224 481 ATP1B1 GO:0050664 oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor 0.806565870794166 -0.214969709867813 16 1 0.000595238095238095 1680 17224 8564 KMO GO:0016668 oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor 0.806565870794166 -0.214969709867813 16 1 0.000595238095238095 1680 17224 114112 TXNRD3 GO:0004935 adrenergic receptor activity 0.806565870794166 -0.214969709867813 16 1 0.000595238095238095 1680 17224 153 ADRB1 GO:0015271 outward rectifier potassium channel activity 0.806565870794166 -0.214969709867813 16 1 0.000595238095238095 1680 17224 3752 KCND3 GO:0005243 gap junction channel activity 0.806565870794166 -0.214969709867813 16 1 0.000595238095238095 1680 17224 10052 GJC1 GO:1990381 ubiquitin-specific protease binding 0.806565870794166 -0.214969709867813 16 1 0.000595238095238095 1680 17224 5071 PRKN GO:0008143 poly(A) binding 0.806565870794166 -0.214969709867813 16 1 0.000595238095238095 1680 17224 202559 KHDRBS2 GO:0001223 transcription coactivator binding 0.806565870794166 -0.214969709867813 16 1 0.000595238095238095 1680 17224 7015 TERT GO:0001664 G-protein coupled receptor binding 0.806864913862573 -0.214599017707138 252 21 0.0125 1680 17224 8643,5071,54550,9826,9693,9455,7481,5028,4734,9454,2770,3627,51704,100506013,2775,65055,153,4040,5144,9863,8321 PTCH2,PRKN,NECAB2,ARHGEF11,RAPGEF2,HOMER2,WNT11,P2RY1,NEDD4,HOMER3,GNAI1,CXCL10,GPRC5B,APELA,GNAO1,REEP1,ADRB1,LRP6,PDE4D,MAGI2,FZD1 GO:0016747 transferase activity, transferring acyl groups other than amino-acyl groups 0.81609891208833 -0.203219715569549 220 18 0.0107142857142857 1680 17224 6785,23464,54947,56895,79993,55301,83401,158866,2194,79683,9227,8435,64429,254887,79603,10715,129642,6296 ELOVL4,GCAT,LPCAT2,AGPAT4,ELOVL7,OLAH,ELOVL3,ZDHHC15,FASN,ZDHHC14,LRAT,SOAT2,ZDHHC6,ZDHHC23,CERS4,CERS1,MBOAT2,ACSM3 GO:0004520 endodeoxyribonuclease activity 0.816564050397515 -0.202649924580891 44 3 0.00178571428571429 1680 17224 2073,79008,200558 ERCC5,SLX1B,APLF GO:0051082 unfolded protein binding 0.81717546307451 -0.201901442095774 117 9 0.00535714285714286 1680 17224 7265,4869,91147,821,871,1047,56605,3306,134266 TTC1,NPM1,TMEM67,CANX,SERPINH1,CLGN,ERO1B,HSPA2,GRPEL2 GO:0016746 transferase activity, transferring acyl groups 0.817709807500043 -0.201247763878499 254 21 0.0125 1680 17224 6785,171425,23464,54947,56895,79993,55301,83401,158866,2194,79683,9227,3157,8435,64429,54814,254887,79603,10715,129642,6296 ELOVL4,CLYBL,GCAT,LPCAT2,AGPAT4,ELOVL7,OLAH,ELOVL3,ZDHHC15,FASN,ZDHHC14,LRAT,HMGCS1,SOAT2,ZDHHC6,QPCTL,ZDHHC23,CERS4,CERS1,MBOAT2,ACSM3 GO:0031625 ubiquitin protein ligase binding 0.818991171327636 -0.199681975006907 310 26 0.0154761904761905 1680 17224 10188,5071,6331,9099,8322,8325,875,114781,5577,958,51429,23710,6497,4088,2861,57761,7466,5002,55353,2272,23111,10891,4091,4281,143384,5567 TNK2,PRKN,SCN5A,USP2,FZD4,FZD8,CBS,BTBD9,PRKAR2B,CD40,SNX9,GABARAPL1,SKI,SMAD3,GPR37,TRIB3,WFS1,SLC22A18,LAPTM4B,FHIT,SPART,PPARGC1A,SMAD6,MID1,CACUL1,PRKACB GO:0016798 hydrolase activity, acting on glycosyl bonds 0.819440771063056 -0.199133157890891 129 10 0.00595238095238095 1680 17224 113622,23324,10855,23670,283310,340485,80267,178,57462,27293 ADPRHL1,MAN2B2,HPSE,CEMIP2,OTOGL,ACER2,EDEM3,AGL,MYORG,SMPDL3B GO:0030332 cyclin binding 0.81961207542136 -0.198924129415336 31 2 0.00119047619047619 1680 17224 9099,10399 USP2,RACK1 GO:1901682 sulfur compound transmembrane transporter activity 0.81961207542136 -0.198924129415336 31 2 0.00119047619047619 1680 17224 23657,10560 SLC7A11,SLC19A2 GO:0030515 snoRNA binding 0.81961207542136 -0.198924129415336 31 2 0.00119047619047619 1680 17224 55651,3669 NHP2,ISG20 GO:0003823 antigen binding 0.819728998594894 -0.198781482865957 57 4 0.00238095238095238 1680 17224 3512,958,1718,8140 JCHAIN,CD40,DHCR24,SLC7A5 GO:0001047 core promoter binding 0.822017952230141 -0.195993044468404 141 11 0.00654761904761905 1680 17224 1051,468,26508,7494,7020,54937,4869,2625,148523,7080,4208 CEBPB,ATF4,HEYL,XBP1,TFAP2A,SOHLH2,NPM1,GATA3,CIART,NKX2-1,MEF2C GO:0061135 endopeptidase regulator activity 0.824672840800658 -0.192768527902083 176 14 0.00833333333333333 1680 17224 27344,2597,1285,1447,51232,8434,720,5274,2621,5627,871,11005,50859,6622 PCSK1N,GAPDH,COL4A3,CSN2,CRIM1,RECK,C4A,SERPINI1,GAS6,PROS1,SERPINH1,SPINK5,SPOCK3,SNCA GO:0002039 p53 binding 0.825313531510278 -0.191991926649403 70 5 0.00297619047619048 1680 17224 54941,4916,4487,29997,25946 RNF125,NTRK3,MSX1,NOP53,ZNF385A GO:0046933 proton-transporting ATP synthase activity, rotational mechanism 0.82545065329739 -0.191825795364645 17 1 0.000595238095238095 1680 17224 92270 ATP6AP1L GO:0000339 RNA cap binding 0.82545065329739 -0.191825795364645 17 1 0.000595238095238095 1680 17224 23367 LARP1 GO:0008329 signaling pattern recognition receptor activity 0.82545065329739 -0.191825795364645 17 1 0.000595238095238095 1680 17224 7099 TLR4 GO:0038187 pattern recognition receptor activity 0.82545065329739 -0.191825795364645 17 1 0.000595238095238095 1680 17224 7099 TLR4 GO:0048019 receptor antagonist activity 0.82545065329739 -0.191825795364645 17 1 0.000595238095238095 1680 17224 22943 DKK1 GO:0004953 icosanoid receptor activity 0.82545065329739 -0.191825795364645 17 1 0.000595238095238095 1680 17224 3248 HPGD GO:0008391 arachidonic acid monooxygenase activity 0.82545065329739 -0.191825795364645 17 1 0.000595238095238095 1680 17224 1573 CYP2J2 GO:0008409 5'-3' exonuclease activity 0.82545065329739 -0.191825795364645 17 1 0.000595238095238095 1680 17224 9941 EXOG GO:0045236 CXCR chemokine receptor binding 0.82545065329739 -0.191825795364645 17 1 0.000595238095238095 1680 17224 3627 CXCL10 GO:0008392 arachidonic acid epoxygenase activity 0.82545065329739 -0.191825795364645 17 1 0.000595238095238095 1680 17224 1573 CYP2J2 GO:0016755 transferase activity, transferring amino-acyl groups 0.82545065329739 -0.191825795364645 17 1 0.000595238095238095 1680 17224 54814 QPCTL GO:0051428 peptide hormone receptor binding 0.82545065329739 -0.191825795364645 17 1 0.000595238095238095 1680 17224 2775 GNAO1 GO:0055106 ubiquitin-protein transferase regulator activity 0.82545065329739 -0.191825795364645 17 1 0.000595238095238095 1680 17224 57761 TRIB3 GO:0030545 receptor regulator activity 0.827242464223856 -0.18965744165212 499 43 0.0255952380952381 1680 17224 685,4681,9235,2258,3958,3600,152189,10673,50810,2621,10584,654,2202,53342,1890,10505,23767,8614,7424,627,2660,79924,8838,7039,2257,8822,22943,3626,3627,10718,2200,7060,1435,100506013,83729,649,9966,3082,10512,652,7292,10371,114336 BTC,NBL1,IL32,FGF13,LGALS3,IL15,CMTM8,TNFSF13B,HDGFL3,GAS6,COLEC10,BMP6,EFEMP1,IL17D,TYMP,SEMA4F,FLRT3,STC2,VEGFC,BDNF,MSTN,ADM2,WISP3,TGFA,FGF12,FGF17,DKK1,INHBC,CXCL10,NRG3,FBN1,THBS4,CSF1,APELA,INHBE,BMP1,TNFSF15,HGF,SEMA3C,BMP4,TNFSF4,SEMA3A,CGB2 GO:0042887 amide transmembrane transporter activity 0.828355189488359 -0.188313243767382 45 3 0.00178571428571429 1680 17224 84976,10560,1015 DISP1,SLC19A2,CDH17 GO:0008170 N-methyltransferase activity 0.830915098080575 -0.185227657720992 95 7 0.00416666666666667 1680 17224 7468,64324,83852,399818,64754,10400,2122 NSD2,NSD1,SETDB2,EEF1AKMT2,SMYD3,PEMT,MECOM GO:0008134 transcription factor binding 0.834014455420802 -0.181504544134747 599 52 0.030952380952381 1680 17224 9658,3397,860,23543,322,2625,4869,10174,1050,6777,5585,7227,6497,8320,2624,10579,51339,4609,23426,23066,23532,468,4212,3164,4774,2274,100271849,10413,9935,6604,23414,6875,256536,23710,473,4088,1051,3399,64324,7015,5579,26508,7466,7494,135112,10891,284252,3169,10736,1649,4208,23462 ZNF516,ID1,RUNX2,RBFOX2,APBB1,GATA3,NPM1,SORBS3,CEBPA,STAT5B,PKN1,TRPS1,SKI,EOMES,GATA2,TACC2,DACT1,MYC,GRIP1,CAND2,PRAME,ATF4,MEIS2,NR4A1,NFIA,FHL2,MEF2B,YAP1,MAFB,SMARCD3,ZFPM2,TAF4B,TCERG1L,GABARAPL1,RERE,SMAD3,CEBPB,ID3,NSD1,TERT,PRKCB,HEYL,WFS1,XBP1,NCOA7,PPARGC1A,KCTD1,FOXA1,SIX2,DDIT3,MEF2C,HEY1 GO:0004722 protein serine/threonine phosphatase activity 0.834574067064828 -0.180833783599761 71 5 0.00297619047619048 1680 17224 22843,5509,5521,8555,27143 PPM1E,PPP1R3D,PPP2R2B,CDC14B,PALD1 GO:0009055 electron transfer activity 0.838549575053801 -0.17608157596773 108 8 0.00476190476190476 1680 17224 56901,217,8974,7358,444,26227,114112,2731 NDUFA4L2,ALDH2,P4HA2,UGDH,ASPH,PHGDH,TXNRD3,GLDC GO:0030414 peptidase inhibitor activity 0.842434299234631 -0.171459602900756 179 14 0.00833333333333333 1680 17224 27344,2597,1285,1447,51232,8434,720,5274,2621,5627,871,11005,50859,6622 PCSK1N,GAPDH,COL4A3,CSN2,CRIM1,RECK,C4A,SERPINI1,GAS6,PROS1,SERPINH1,SPINK5,SPOCK3,SNCA GO:0019789 SUMO transferase activity 0.842492723523391 -0.171390253560405 18 1 0.000595238095238095 1680 17224 5903 RANBP2 GO:0070577 lysine-acetylated histone binding 0.842492723523391 -0.171390253560405 18 1 0.000595238095238095 1680 17224 4300 MLLT3 GO:0055102 lipase inhibitor activity 0.842492723523391 -0.171390253560405 18 1 0.000595238095238095 1680 17224 6622 SNCA GO:0140142 nucleocytoplasmic carrier activity 0.842492723523391 -0.171390253560405 18 1 0.000595238095238095 1680 17224 3839 KPNA3 GO:0097602 cullin family protein binding 0.842492723523391 -0.171390253560405 18 1 0.000595238095238095 1680 17224 5071 PRKN GO:0140033 acetylation-dependent protein binding 0.842492723523391 -0.171390253560405 18 1 0.000595238095238095 1680 17224 4300 MLLT3 GO:0015301 anion:anion antiporter activity 0.845828012741 -0.167439234675456 33 2 0.00119047619047619 1680 17224 54020,23657 SLC37A1,SLC7A11 GO:0005048 signal sequence binding 0.849994834145593 -0.162525006992016 47 3 0.00178571428571429 1680 17224 51555,3839,3843 PEX5L,KPNA3,IPO5 GO:0044769 ATPase activity, coupled to transmembrane movement of ions, rotational mechanism 0.857593599913077 -0.153624951481369 34 2 0.00119047619047619 1680 17224 90423,92270 ATP6V1E2,ATP6AP1L GO:0022840 leak channel activity 0.857871790394329 -0.153300619104555 19 1 0.000595238095238095 1680 17224 60598 KCNK15 GO:0042288 MHC class I protein binding 0.857871790394329 -0.153300619104555 19 1 0.000595238095238095 1680 17224 10859 LILRB1 GO:0016922 ligand-dependent nuclear receptor binding 0.857871790394329 -0.153300619104555 19 1 0.000595238095238095 1680 17224 10891 PPARGC1A GO:0003746 translation elongation factor activity 0.857871790394329 -0.153300619104555 19 1 0.000595238095238095 1680 17224 1938 EEF2 GO:0022842 narrow pore channel activity 0.857871790394329 -0.153300619104555 19 1 0.000595238095238095 1680 17224 60598 KCNK15 GO:0016780 phosphotransferase activity, for other substituted phosphate groups 0.857871790394329 -0.153300619104555 19 1 0.000595238095238095 1680 17224 1040 CDS1 GO:0099095 ligand-gated anion channel activity 0.857871790394329 -0.153300619104555 19 1 0.000595238095238095 1680 17224 2566 GABRG2 GO:0000062 fatty-acyl-CoA binding 0.857871790394329 -0.153300619104555 19 1 0.000595238095238095 1680 17224 8435 SOAT2 GO:0016895 exodeoxyribonuclease activity, producing 5'-phosphomonoesters 0.857871790394329 -0.153300619104555 19 1 0.000595238095238095 1680 17224 3669 ISG20 GO:0004529 exodeoxyribonuclease activity 0.857871790394329 -0.153300619104555 19 1 0.000595238095238095 1680 17224 3669 ISG20 GO:0042393 histone binding 0.860719039877788 -0.149987146184386 194 15 0.00892857142857143 1680 17224 80853,10765,5579,81550,10360,1515,322,51460,4869,26108,5585,4300,26038,83666,6622 KDM7A,KDM5B,PRKCB,TDRD3,NPM3,CTSV,APBB1,SFMBT1,NPM1,PYGO1,PKN1,MLLT3,CHD5,PARP9,SNCA GO:0003712 transcription cofactor activity 0.867629625974593 -0.141990353569315 566 48 0.0285714285714286 1680 17224 29842,4601,23051,23543,29995,6756,2625,4869,1488,1050,5585,64900,6497,7020,23426,9443,8531,116931,30818,4212,10765,81550,84159,4779,2274,10413,23286,6604,467,23414,6875,256536,55509,473,9149,57761,9242,64324,3399,11278,5579,26508,25937,135112,51460,10891,284252,1649 TFCP2L1,MXI1,ZHX3,RBFOX2,LMCD1,SSX1,GATA3,NPM1,CTBP2,CEBPA,PKN1,LPIN3,SKI,TFAP2A,GRIP1,MED7,YBX3,MED12L,KCNIP3,MEIS2,KDM5B,TDRD3,ARID5B,NFE2L1,FHL2,YAP1,WWC1,SMARCD3,ATF3,ZFPM2,TAF4B,TCERG1L,BATF3,RERE,DYRK1B,TRIB3,MSC,NSD1,ID3,KLF12,PRKCB,HEYL,WWTR1,NCOA7,SFMBT1,PPARGC1A,KCTD1,DDIT3 GO:0008395 steroid hydroxylase activity 0.868532420586481 -0.140950364594731 35 2 0.00119047619047619 1680 17224 113612,1573 CYP2U1,CYP2J2 GO:0016814 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines 0.868532420586481 -0.140950364594731 35 2 0.00119047619047619 1680 17224 161823,270 ADAL,AMPD1 GO:0016881 acid-amino acid ligase activity 0.871750046265817 -0.137252540354033 20 1 0.000595238095238095 1680 17224 79739 TTLL7 GO:0022884 macromolecule transmembrane transporter activity 0.871750046265817 -0.137252540354033 20 1 0.000595238095238095 1680 17224 54847 SIDT1 GO:0023023 MHC protein complex binding 0.871750046265817 -0.137252540354033 20 1 0.000595238095238095 1680 17224 481 ATP1B1 GO:0031420 alkali metal ion binding 0.871750046265817 -0.137252540354033 20 1 0.000595238095238095 1680 17224 481 ATP1B1 GO:0005212 structural constituent of eye lens 0.871750046265817 -0.137252540354033 20 1 0.000595238095238095 1680 17224 7431 VIM GO:0004252 serine-type endopeptidase activity 0.87379777791682 -0.134906305479228 185 14 0.00833333333333333 1680 17224 6768,8492,360200,720,1515,649,3082,715,2161,10584,7093,5046,2152,5125 ST14,PRSS12,TMPRSS9,C4A,CTSV,BMP1,HGF,C1R,F12,COLEC10,TLL2,PCSK6,F3,PCSK5 GO:0031072 heat shock protein binding 0.877970652077396 -0.130142111785637 114 8 0.00476190476190476 1680 17224 2861,5071,2633,4597,2081,10960,3306,6622 GPR37,PRKN,GBP1,MVD,ERN1,LMAN2,HSPA2,SNCA GO:0035064 methylated histone binding 0.882403859395096 -0.125105437304566 64 4 0.00238095238095238 1680 17224 80853,26108,81550,26038 KDM7A,PYGO1,TDRD3,CHD5 GO:0070491 repressing transcription factor binding 0.882403859395096 -0.125105437304566 64 4 0.00238095238095238 1680 17224 860,256536,4609,6497 RUNX2,TCERG1L,MYC,SKI GO:0140034 methylation-dependent protein binding 0.882403859395096 -0.125105437304566 64 4 0.00238095238095238 1680 17224 80853,26108,81550,26038 KDM7A,PYGO1,TDRD3,CHD5 GO:0004536 deoxyribonuclease activity 0.882403859395096 -0.125105437304566 64 4 0.00238095238095238 1680 17224 2073,79008,200558,3669 ERCC5,SLX1B,APLF,ISG20 GO:0051184 cofactor transmembrane transporter activity 0.884273873418797 -0.12298845276646 21 1 0.000595238095238095 1680 17224 55640 FLVCR2 GO:0102568 phospholipase A2 activity consuming 1,2-dioleoylphosphatidylethanolamine) 0.884273873418797 -0.12298845276646 21 1 0.000595238095238095 1680 17224 5321 PLA2G4A GO:0102567 phospholipase A2 activity (consuming 1,2-dipalmitoylphosphatidylcholine) 0.884273873418797 -0.12298845276646 21 1 0.000595238095238095 1680 17224 5321 PLA2G4A GO:0016502 nucleotide receptor activity 0.884273873418797 -0.12298845276646 21 1 0.000595238095238095 1680 17224 5028 P2RY1 GO:0005242 inward rectifier potassium channel activity 0.884273873418797 -0.12298845276646 21 1 0.000595238095238095 1680 17224 3761 KCNJ4 GO:0001614 purinergic nucleotide receptor activity 0.884273873418797 -0.12298845276646 21 1 0.000595238095238095 1680 17224 5028 P2RY1 GO:1901338 catecholamine binding 0.884273873418797 -0.12298845276646 21 1 0.000595238095238095 1680 17224 153 ADRB1 GO:0050750 low-density lipoprotein particle receptor binding 0.884273873418797 -0.12298845276646 21 1 0.000595238095238095 1680 17224 22943 DKK1 GO:0008327 methyl-CpG binding 0.884273873418797 -0.12298845276646 21 1 0.000595238095238095 1680 17224 253461 ZBTB38 GO:0008270 zinc ion binding 0.885469085099362 -0.121637734735316 792 68 0.0404761904761905 1680 17224 5071,57643,23321,10626,29995,79710,2625,11237,5578,767,7227,6497,64376,83852,25924,4661,1363,10125,153830,2649,26136,54941,253827,377677,6622,4088,114088,5167,81931,53840,5579,5066,649,4306,4281,9871,219654,80853,760,2624,10612,115123,119587,166336,25946,10924,11043,10765,3174,2104,3164,1397,6920,9516,144165,79740,23414,473,4324,64324,9508,91133,7761,54814,4325,4311,1911,7093 PRKN,ZSWIM5,TRIM2,TRIM16,LMCD1,MORC4,GATA3,RNF24,PRKCA,CA8,TRPS1,SKI,IKZF5,SETDB2,MYRIP,MYT1,CPE,RASGRP1,RNF145,NR6A1,TES,RNF125,MSRB3,CA13,SNCA,SMAD3,TRIM9,ENPP1,ZNF93,TRIM34,PRKCB,PAM,BMP1,NR3C2,MID1,SEC24D,ZCCHC24,KDM7A,CA2,GATA2,TRIM3,MARCH3,CPXM2,PRICKLE2,ZNF385A,SMPDL3A,MID2,KDM5B,HNF4G,ESRRG,NR4A1,CRIP2,TCEA3,LITAF,PRICKLE1,ZBBX,ZFPM2,RERE,MMP15,NSD1,ADAMTS3,L3MBTL4,ZNF214,QPCTL,MMP16,MME,PHC1,TLL2 GO:0016831 carboxy-lyase activity 0.888124970052144 -0.118642813851089 37 2 0.00119047619047619 1680 17224 5106,4597 PCK2,MVD GO:0046914 transition metal ion binding 0.89375880606417 -0.112319332083528 1046 91 0.0541666666666667 1680 17224 5071,57643,23321,10626,29995,79710,2625,11237,144811,5578,767,1592,7227,6497,1595,10247,64376,83852,25924,4661,1363,10125,1545,153830,2649,26136,475,54941,253827,377677,6622,4088,114088,5167,81931,53840,5579,8974,540,5066,649,5033,113612,4306,4281,55034,9871,1573,219654,285440,6319,80853,2589,760,2624,6307,115123,10612,119587,166336,84171,26002,5106,25946,10924,4846,11043,10765,3174,2104,3164,1397,9516,6920,144165,79740,23414,473,4324,2591,64324,5352,9508,91133,7761,54814,4325,11285,4311,7093,1911 PRKN,ZSWIM5,TRIM2,TRIM16,LMCD1,MORC4,GATA3,RNF24,LACC1,PRKCA,CA8,CYP26A1,TRPS1,SKI,CYP51A1,RIDA,IKZF5,SETDB2,MYRIP,MYT1,CPE,RASGRP1,CYP1B1,RNF145,NR6A1,TES,ATOX1,RNF125,MSRB3,CA13,SNCA,SMAD3,TRIM9,ENPP1,ZNF93,TRIM34,PRKCB,P4HA2,ATP7B,PAM,BMP1,P4HA1,CYP2U1,NR3C2,MID1,MOCOS,SEC24D,CYP2J2,ZCCHC24,CYP4V2,SCD,KDM7A,GALNT1,CA2,GATA2,MSMO1,MARCH3,TRIM3,CPXM2,PRICKLE2,LOXL4,MOXD1,PCK2,ZNF385A,SMPDL3A,NOS3,MID2,KDM5B,HNF4G,ESRRG,NR4A1,CRIP2,LITAF,TCEA3,PRICKLE1,ZBBX,ZFPM2,RERE,MMP15,GALNT3,NSD1,PLOD2,ADAMTS3,L3MBTL4,ZNF214,QPCTL,MMP16,B4GALT7,MME,TLL2,PHC1 GO:0070530 K63-linked polyubiquitin modification-dependent protein binding 0.895575384374377 -0.110288879701832 22 1 0.000595238095238095 1680 17224 199990 FAAP20 GO:0008198 ferrous iron binding 0.895575384374377 -0.110288879701832 22 1 0.000595238095238095 1680 17224 6622 SNCA GO:0004867 serine-type endopeptidase inhibitor activity 0.901121275624607 -0.104115429294531 93 6 0.00357142857142857 1680 17224 5274,27344,871,51232,11005,8434 SERPINI1,PCSK1N,SERPINH1,CRIM1,SPINK5,RECK GO:0043022 ribosome binding 0.901237638988559 -0.103986305885014 53 3 0.00178571428571429 1680 17224 10399,1938,64506 RACK1,EEF2,CPEB1 GO:0051879 Hsp90 protein binding 0.904978006597273 -0.0998446376799721 39 2 0.00119047619047619 1680 17224 2633,2081 GBP1,ERN1 GO:0070717 poly-purine tract binding 0.905773812076141 -0.0989656596533896 23 1 0.000595238095238095 1680 17224 202559 KHDRBS2 GO:0022829 wide pore channel activity 0.905773812076141 -0.0989656596533896 23 1 0.000595238095238095 1680 17224 10052 GJC1 GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds 0.905773812076141 -0.0989656596533896 23 1 0.000595238095238095 1680 17224 113622 ADPRHL1 GO:0015108 chloride transmembrane transporter activity 0.906465973433609 -0.098201785692936 94 6 0.00357142857142857 1680 17224 2566,94015,55129,2570,9990,2561 GABRG2,TTYH2,ANO10,GABRR2,SLC12A6,GABRB2 GO:0003725 double-stranded RNA binding 0.908938163218766 -0.0954782143807011 68 4 0.00238095238095238 1680 17224 7431,192670,7098,6520 VIM,AGO4,TLR3,SLC3A2 GO:0005254 chloride channel activity 0.91215354842673 -0.0919469385765242 82 5 0.00297619047619048 1680 17224 2566,94015,55129,2570,2561 GABRG2,TTYH2,ANO10,GABRR2,GABRB2 GO:0017069 snRNA binding 0.912485151264191 -0.0915834662450782 40 2 0.00119047619047619 1680 17224 134353,3669 LSM11,ISG20 GO:0042623 ATPase activity, coupled 0.912847617770567 -0.0911863150874489 381 30 0.0178571428571429 1680 17224 4642,10257,4651,10079,3798,10396,4430,90423,3800,1244,23250,481,1780,57205,55760,1768,23461,540,51626,79659,55137,144132,1767,3306,23095,92270,493,490,478,9619 MYO1D,ABCC4,MYO10,ATP9A,KIF5A,ATP8A1,MYO1B,ATP6V1E2,KIF5C,ABCC2,ATP11A,ATP1B1,DYNC1I1,ATP10D,DHX32,DNAH6,ABCA5,ATP7B,DYNC2LI1,DYNC2H1,FIGN,DNHD1,DNAH5,HSPA2,KIF1B,ATP6AP1L,ATP2B4,ATP2B1,ATP1A3,ABCG1 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity 0.914679752407904 -0.0891812723384008 69 4 0.00238095238095238 1680 17224 5585,10891,5579,135112 PKN1,PPARGC1A,PRKCB,NCOA7 GO:0016676 oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor 0.914976765182238 -0.0888566072724853 24 1 0.000595238095238095 1680 17224 56901 NDUFA4L2 GO:0004129 cytochrome-c oxidase activity 0.914976765182238 -0.0888566072724853 24 1 0.000595238095238095 1680 17224 56901 NDUFA4L2 GO:0000217 DNA secondary structure binding 0.914976765182238 -0.0888566072724853 24 1 0.000595238095238095 1680 17224 2073 ERCC5 GO:0017025 TBP-class protein binding 0.914976765182238 -0.0888566072724853 24 1 0.000595238095238095 1680 17224 23066 CAND2 GO:0015002 heme-copper terminal oxidase activity 0.914976765182238 -0.0888566072724853 24 1 0.000595238095238095 1680 17224 56901 NDUFA4L2 GO:0030547 receptor inhibitor activity 0.914976765182238 -0.0888566072724853 24 1 0.000595238095238095 1680 17224 22943 DKK1 GO:1990841 promoter-specific chromatin binding 0.919432925308872 -0.0839981845165464 41 2 0.00119047619047619 1680 17224 639,10891 PRDM1,PPARGC1A GO:0005501 retinoid binding 0.919432925308872 -0.0839981845165464 41 2 0.00119047619047619 1680 17224 9227,1592 LRAT,CYP26A1 GO:0070063 RNA polymerase binding 0.920095887051081 -0.0832773893145822 70 4 0.00238095238095238 1680 17224 256536,64754,4734,2040 TCERG1L,SMYD3,NEDD4,STOM GO:0016675 oxidoreductase activity, acting on a heme group of donors 0.923281360182198 -0.0798212586644636 25 1 0.000595238095238095 1680 17224 56901 NDUFA4L2 GO:0035198 miRNA binding 0.923281360182198 -0.0798212586644636 25 1 0.000595238095238095 1680 17224 192670 AGO4 GO:0035586 purinergic receptor activity 0.923281360182198 -0.0798212586644636 25 1 0.000595238095238095 1680 17224 5028 P2RY1 GO:0015605 organophosphate ester transmembrane transporter activity 0.923281360182198 -0.0798212586644636 25 1 0.000595238095238095 1680 17224 54020 SLC37A1 GO:0019956 chemokine binding 0.923281360182198 -0.0798212586644636 25 1 0.000595238095238095 1680 17224 3690 ITGB3 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 0.925082937933809 -0.0778718828580205 149 10 0.00595238095238095 1680 17224 56896,8875,23576,26873,161823,138151,158584,340485,144193,270 DPYSL5,VNN2,DDAH1,OPLAH,ADAL,NACC2,FAAH2,ACER2,AMDHD1,AMPD1 GO:0005253 anion channel activity 0.925419761342099 -0.0775078483584855 98 6 0.00357142857142857 1680 17224 2566,94015,55129,2570,23507,2561 GABRG2,TTYH2,ANO10,GABRR2,LRRC8B,GABRB2 GO:0044183 protein binding involved in protein folding 0.925858949141513 -0.0770333786795908 42 2 0.00119047619047619 1680 17224 1047,3306 CLGN,HSPA2 GO:0004869 cysteine-type endopeptidase inhibitor activity 0.926005340657633 -0.0768752769037421 57 3 0.00178571428571429 1680 17224 2621,1447,6622 GAS6,CSN2,SNCA GO:0004950 chemokine receptor activity 0.930775244447456 -0.0717374439031083 26 1 0.000595238095238095 1680 17224 643 CXCR5 GO:0001637 G-protein coupled chemoattractant receptor activity 0.930775244447456 -0.0717374439031083 26 1 0.000595238095238095 1680 17224 643 CXCR5 GO:0016866 intramolecular transferase activity 0.930775244447456 -0.0717374439031083 26 1 0.000595238095238095 1680 17224 283209 PGM2L1 GO:0003950 NAD+ ADP-ribosyltransferase activity 0.930775244447456 -0.0717374439031083 26 1 0.000595238095238095 1680 17224 83666 PARP9 GO:0035035 histone acetyltransferase binding 0.930775244447456 -0.0717374439031083 26 1 0.000595238095238095 1680 17224 1051 CEBPB GO:0090482 vitamin transmembrane transporter activity 0.930775244447456 -0.0717374439031083 26 1 0.000595238095238095 1680 17224 10560 SLC19A2 GO:0070325 lipoprotein particle receptor binding 0.930775244447456 -0.0717374439031083 26 1 0.000595238095238095 1680 17224 22943 DKK1 GO:0019840 isoprenoid binding 0.931798831031028 -0.0706383341279929 43 2 0.00119047619047619 1680 17224 9227,1592 LRAT,CYP26A1 GO:0016741 transferase activity, transferring one-carbon groups 0.932996157016999 -0.0693541970961171 225 16 0.00952380952380952 1680 17224 1787,64324,83852,399818,59336,160428,10400,10840,221078,7468,56978,639,2628,64754,4255,2122 TRDMT1,NSD1,SETDB2,EEF1AKMT2,PRDM13,ALDH1L2,PEMT,ALDH1L1,NSUN6,NSD2,PRDM8,PRDM1,GATM,SMYD3,MGMT,MECOM GO:0002020 protease binding 0.933195400892602 -0.0691406671661217 126 8 0.00476190476190476 1680 17224 6402,5071,2335,147372,3949,3690,4102,2152 SELL,PRKN,FN1,CCBE1,LDLR,ITGB3,MAGEA3,F3 GO:0047485 protein N-terminus binding 0.933564146751925 -0.0687456019692299 100 6 0.00357142857142857 1680 17224 2073,241,9143,6812,7015,6622 ERCC5,ALOX5AP,SYNGR3,STXBP1,TERT,SNCA GO:0004197 cysteine-type endopeptidase activity 0.935314232158471 -0.0668727289798986 87 5 0.00297619047619048 1680 17224 25801,9099,84749,1515,726 GCA,USP2,USP30,CTSV,CAPN5 GO:0046966 thyroid hormone receptor binding 0.937537518495201 -0.0644985022101246 27 1 0.000595238095238095 1680 17224 64324 NSD1 GO:0070566 adenylyltransferase activity 0.937537518495201 -0.0644985022101246 27 1 0.000595238095238095 1680 17224 349565 NMNAT3 GO:0004806 triglyceride lipase activity 0.937537518495201 -0.0644985022101246 27 1 0.000595238095238095 1680 17224 23491 CES3 GO:0017056 structural constituent of nuclear pore 0.937537518495201 -0.0644985022101246 27 1 0.000595238095238095 1680 17224 54830 NUP62CL GO:0001671 ATPase activator activity 0.937537518495201 -0.0644985022101246 27 1 0.000595238095238095 1680 17224 481 ATP1B1 GO:0031593 polyubiquitin modification-dependent protein binding 0.947028332260492 -0.0544262683338839 46 2 0.00119047619047619 1680 17224 178,199990 AGL,FAAP20 GO:0015103 inorganic anion transmembrane transporter activity 0.947501882265127 -0.0539263554680283 169 11 0.00654761904761905 1680 17224 55129,54020,51310,10257,23507,2561,94015,2566,1244,9990,2570 ANO10,SLC37A1,SLC22A17,ABCC4,LRRC8B,GABRB2,TTYH2,GABRG2,ABCC2,SLC12A6,GABRR2 GO:0005125 cytokine activity 0.948106015770446 -0.0532889519982502 219 15 0.00892857142857143 1680 17224 53342,3626,3627,9235,3600,2660,1435,152189,10673,83729,649,9966,652,7292,654 IL17D,INHBC,CXCL10,IL32,IL15,MSTN,CSF1,CMTM8,TNFSF13B,INHBE,BMP1,TNFSF15,BMP4,TNFSF4,BMP6 GO:0004033 aldo-keto reductase (NADP) activity 0.949145822215589 -0.0521928333613535 29 1 0.000595238095238095 1680 17224 7881 KCNAB1 GO:0008237 metallopeptidase activity 0.95089008646968 -0.0503567999094449 183 12 0.00714285714285714 1680 17224 170691,4324,89782,9508,649,119587,11174,1363,4325,4311,254042,7093 ADAMTS17,MMP15,LMLN,ADAMTS3,BMP1,CPXM2,ADAMTS6,CPE,MMP16,MME,METAP1D,TLL2 GO:0003713 transcription coactivator activity 0.951050269702473 -0.0501883579994218 317 23 0.0136904761904762 1680 17224 81550,84159,2274,10413,2625,23286,4869,6604,1050,23414,5585,64900,6875,473,9149,5579,25937,135112,7020,23426,9443,10891,116931 TDRD3,ARID5B,FHL2,YAP1,GATA3,WWC1,NPM1,SMARCD3,CEBPA,ZFPM2,PKN1,LPIN3,TAF4B,RERE,DYRK1B,PRKCB,WWTR1,NCOA7,TFAP2A,GRIP1,MED7,PPARGC1A,MED12L GO:1901618 organic hydroxy compound transmembrane transporter activity 0.951340932190218 -0.0498827820592923 47 2 0.00119047619047619 1680 17224 114134,9619 SLC2A13,ABCG1 GO:0140030 modification-dependent protein binding 0.951517147022329 -0.0496975713653999 132 8 0.00476190476190476 1680 17224 80853,26108,178,81550,26038,4300,5777,199990 KDM7A,PYGO1,AGL,TDRD3,CHD5,MLLT3,PTPN6,FAAP20 GO:0008565 protein transporter activity 0.952845117901506 -0.0483029091008849 92 5 0.00297619047619048 1680 17224 10203,83548,3839,23209,3843 CALCRL,COG3,KPNA3,MLC1,IPO5 GO:0042287 MHC protein binding 0.954114418792295 -0.0469716788845985 30 1 0.000595238095238095 1680 17224 10859 LILRB1 GO:0005179 hormone activity 0.954795811167304 -0.0462577716581034 120 7 0.00416666666666667 1680 17224 3626,2200,79924,100506013,8614,114336,83729 INHBC,FBN1,ADM2,APELA,STC2,CGB2,INHBE GO:0001221 transcription cofactor binding 0.958597830272685 -0.0422836556926283 31 1 0.000595238095238095 1680 17224 7015 TERT GO:0000175 3'-5'-exoribonuclease activity 0.958597830272685 -0.0422836556926283 31 1 0.000595238095238095 1680 17224 3669 ISG20 GO:0031490 chromatin DNA binding 0.958788833067608 -0.042084423269448 108 6 0.00357142857142857 1680 17224 4088,7546,474,10891,29841,604 SMAD3,ZIC2,ATOH1,PPARGC1A,GRHL1,BCL6 GO:0016787 hydrolase activity 0.959350891628827 -0.0414983777691448 2568 227 0.135119047619048 1680 17224 57530,196463,161823,5153,1850,8492,3798,10396,11099,51175,11174,63874,57406,5881,16,2070,2152,113622,10382,8153,22843,54504,1768,158584,5911,27143,144110,25837,744,5521,5791,1363,79605,51062,10257,23670,120892,726,9829,284161,8612,27351,1244,2161,64943,2770,5167,10855,133121,57089,540,2081,649,2073,22876,148252,144132,58528,5125,3636,9886,5789,283310,84959,55301,90423,65997,122622,1780,5217,26038,80055,57462,220213,760,1938,590,23461,200558,25825,10846,119587,57552,55137,178,1131,56896,23433,4651,80267,2194,1852,5151,715,51390,64077,23236,144193,55760,747,4324,9508,51626,11031,5799,5337,270,4311,5321,92170,170685,26052,6768,29984,720,4430,84945,64900,10584,23046,83594,91351,9372,8611,10247,3422,8555,140469,9805,22989,2272,5144,379,5874,1767,3306,92270,57110,57628,8875,54961,25801,2617,7846,10076,5208,79875,5777,57502,92370,481,23682,57205,254042,3669,953,5795,89782,2633,360200,8821,142679,5802,3082,5413,5723,27314,23324,4642,10279,10079,23621,3800,402,51655,79008,147111,84749,3628,81544,23551,2963,79659,9896,4646,22800,55964,2098,490,10924,23491,5046,1843,5210,5509,26873,9099,5865,51560,5783,389643,116986,23250,7347,9941,27293,2822,170691,5788,23576,138151,390,64748,5547,340485,2775,1515,55605,745,2669,23095,4325,493,478,9619,7093,200035 CGN,PLBD2,ADAL,PDE1B,DUSP8,PRSS12,KIF5A,ATP8A1,PTPN21,TUBE1,ADAMTS6,ABHD4,ABHD6,RAC3,AARS,EYA4,F3,ADPRHL1,TUBB4A,RND2,PPM1E,CPVL,DNAH6,FAAH2,RAP2A,PALD1,TMEM86A,RAB26,MPPED2,PPP2R2B,PTPRE,CPE,PGBD5,ATL1,ABCC4,CEMIP2,LRRK2,CAPN5,DNAJC6,GDPD1,PLPP2,DESI1,ABCC2,F12,NT5DC2,GNAI1,ENPP1,HPSE,ENPP6,ENTPD7,ATP7B,ERN1,BMP1,ERCC5,INPP5F,DIRAS1,DNHD1,RRAGD,PCSK5,INPPL1,RHOBTB1,PTPRD,OTOGL,UBASH3B,OLAH,ATP6V1E2,RASL11B,ADSSL1,DYNC1I1,PFN2,CHD5,PGAP1,MYORG,OTUD1,CA2,EEF2,BCHE,ABCA5,APLF,BACE2,PDE10A,CPXM2,NCEH1,FIGN,AGL,CHRM3,DPYSL5,RHOQ,MYO10,EDEM3,FASN,DUSP9,PDE8A,C1R,AIG1,LHPP,PLCB1,AMDHD1,DHX32,DAGLA,MMP15,ADAMTS3,DYNC2LI1,RAB31,PTPRN2,PLD1,AMPD1,MME,PLA2G4A,MTG1,NUDT10,DNM3,ST14,RHOD,C4A,MYO1B,ABHD13,LPIN3,COLEC10,KIF21B,NUDT12,DDX60L,ZFYVE9,PLPP1,RIDA,IDI1,CDC14B,MYO3B,SCRN1,MYH15,FHIT,PDE4D,ARL4D,RAB27B,DNAH5,HSPA2,ATP6AP1L,HRASLS,DPP10,VNN2,SSH3,GCA,GARS,TUBA1A,PTPRU,PFKFB2,THSD4,PTPN6,NLGN4X,PXYLP1,ATP1B1,RAB38,ATP10D,METAP1D,ISG20,ENTPD1,PTPRJ,LMLN,GBP1,TMPRSS9,INPP4B,DUSP19,PTPRS,HGF,SEPT5,PSPH,RAB30,MAN2B2,MYO1D,PRSS16,ATP9A,BACE1,KIF5C,ARL2,RASD1,SLX1B,NOTUM,USP30,INPP1,GDPD5,RASD2,GTF2F2,DYNC2H1,FIG4,MYO6,RRAS2,SEPT3,ESD,ATP2B1,SMPDL3A,CES3,PCSK6,DUSP1,PFKFB4,PPP1R3D,OPLAH,USP2,RAB3B,RAB6B,PTPN13,NUGGC,AGAP2,ATP11A,UCHL3,EXOG,SMPDL3B,GPLD1,ADAMTS17,PTPRC,DDAH1,NACC2,RND3,PLPPR2,PRCP,ACER2,GNAO1,CTSV,KIF21A,MYRF,GEM,KIF1B,MMP16,ATP2B4,ATP1A3,ABCG1,TLL2,NUDT17 GO:0004843 thiol-dependent ubiquitin-specific protease activity 0.959475178157556 -0.0413688334286134 80 4 0.00238095238095238 1680 17224 220213,9099,84749,7347 OTUD1,USP2,USP30,UCHL3 GO:0140101 catalytic activity, acting on a tRNA 0.962010413122392 -0.0387300039234639 123 7 0.00416666666666667 1680 17224 833,1787,4141,2617,16,221078,7453 CARS,TRDMT1,MARS,GARS,AARS,NSUN6,WARS GO:0004527 exonuclease activity 0.962215245750864 -0.0385171051625509 81 4 0.00238095238095238 1680 17224 5167,9941,200558,3669 ENPP1,EXOG,APLF,ISG20 GO:0003743 translation initiation factor activity 0.962355364201829 -0.0383714950711483 50 2 0.00119047619047619 1680 17224 317649,10209 EIF4E3,EIF1 GO:0016229 steroid dehydrogenase activity 0.962643409587313 -0.0380722269453123 32 1 0.000595238095238095 1680 17224 79644 SRD5A3 GO:0001530 lipopolysaccharide binding 0.962643409587313 -0.0380722269453123 32 1 0.000595238095238095 1680 17224 7099 TLR4 GO:0003727 single-stranded RNA binding 0.964782512294489 -0.0358525789047405 82 4 0.00238095238095238 1680 17224 192670,1746,54033,202559 AGO4,DLX2,RBM11,KHDRBS2 GO:0001103 RNA polymerase II repressing transcription factor binding 0.966293890688823 -0.034287256372083 33 1 0.000595238095238095 1680 17224 256536 TCERG1L GO:0005452 inorganic anion exchanger activity 0.966293890688823 -0.034287256372083 33 1 0.000595238095238095 1680 17224 51310 SLC22A17 GO:0016896 exoribonuclease activity, producing 5'-phosphomonoesters 0.966293890688823 -0.034287256372083 33 1 0.000595238095238095 1680 17224 3669 ISG20 GO:0008408 3'-5' exonuclease activity 0.968322105287562 -0.0321904936594516 52 2 0.00119047619047619 1680 17224 200558,3669 APLF,ISG20 GO:0004623 phospholipase A2 activity 0.969587838899324 -0.0308842061350548 34 1 0.000595238095238095 1680 17224 5321 PLA2G4A GO:0061980 regulatory RNA binding 0.969587838899324 -0.0308842061350548 34 1 0.000595238095238095 1680 17224 192670 AGO4 GO:0043539 protein serine/threonine kinase activator activity 0.969587838899324 -0.0308842061350548 34 1 0.000595238095238095 1680 17224 10253 SPRY2 GO:0030331 estrogen receptor binding 0.969587838899324 -0.0308842061350548 34 1 0.000595238095238095 1680 17224 64324 NSD1 GO:0004693 cyclin-dependent protein serine/threonine kinase activity 0.972560057094101 -0.0278234500296349 35 1 0.000595238095238095 1680 17224 5891 MOK GO:0016893 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 0.972560057094101 -0.0278234500296349 35 1 0.000595238095238095 1680 17224 79008 SLX1B GO:0008757 S-adenosylmethionine-dependent methyltransferase activity 0.973127925867034 -0.0272397297270679 156 9 0.00535714285714286 1680 17224 1787,64324,83852,399818,10400,221078,7468,64754,2122 TRDMT1,NSD1,SETDB2,EEF1AKMT2,PEMT,NSUN6,NSD2,SMYD3,MECOM GO:0004519 endonuclease activity 0.973398158407294 -0.0269620735022899 129 7 0.00416666666666667 1680 17224 2073,10247,79008,9941,200558,2081,79605 ERCC5,RIDA,SLX1B,EXOG,APLF,ERN1,PGBD5 GO:0097472 cyclin-dependent protein kinase activity 0.975241952749503 -0.0250696821039055 36 1 0.000595238095238095 1680 17224 5891 MOK GO:0008135 translation factor activity, RNA binding 0.975352926019723 -0.0249558980767378 87 4 0.00238095238095238 1680 17224 317649,1938,10209,64506 EIF4E3,EEF2,EIF1,CPEB1 GO:0016887 ATPase activity 0.976104146542122 -0.024185990739221 456 33 0.0196428571428571 1680 17224 4642,10079,3798,10396,4430,90423,3800,23046,1780,5217,1768,23461,79659,55137,1767,3306,92270,490,10257,4651,1244,481,23250,57205,55760,540,51626,55605,144132,23095,493,9619,478 MYO1D,ATP9A,KIF5A,ATP8A1,MYO1B,ATP6V1E2,KIF5C,KIF21B,DYNC1I1,PFN2,DNAH6,ABCA5,DYNC2H1,FIGN,DNAH5,HSPA2,ATP6AP1L,ATP2B1,ABCC4,MYO10,ABCC2,ATP1B1,ATP11A,ATP10D,DHX32,ATP7B,DYNC2LI1,KIF21A,DNHD1,KIF1B,ATP2B4,ABCG1,ATP1A3 GO:0042162 telomeric DNA binding 0.977661868916923 -0.0225914060320008 37 1 0.000595238095238095 1680 17224 7015 TERT GO:1901505 carbohydrate derivative transmembrane transporter activity 0.977661868916923 -0.0225914060320008 37 1 0.000595238095238095 1680 17224 54020 SLC37A1 GO:0034061 DNA polymerase activity 0.977661868916923 -0.0225914060320008 37 1 0.000595238095238095 1680 17224 7015 TERT GO:0008168 methyltransferase activity 0.978663640652743 -0.021567269896701 213 13 0.00773809523809524 1680 17224 1787,64324,83852,399818,59336,10400,221078,7468,56978,639,64754,4255,2122 TRDMT1,NSD1,SETDB2,EEF1AKMT2,PRDM13,PEMT,NSUN6,NSD2,PRDM8,PRDM1,SMYD3,MGMT,MECOM GO:0004521 endoribonuclease activity 0.979517764705792 -0.0206949052578798 57 2 0.00119047619047619 1680 17224 10247,2081 RIDA,ERN1 GO:0004532 exoribonuclease activity 0.979845383263711 -0.0203604919447456 38 1 0.000595238095238095 1680 17224 3669 ISG20 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides 0.98017982171101 -0.0200192326081863 90 4 0.00238095238095238 1680 17224 8875,138151,158584,340485 VNN2,NACC2,FAAH2,ACER2 GO:0019213 deacetylase activity 0.981242115260508 -0.0189360453211064 58 2 0.00119047619047619 1680 17224 138151,2098 NACC2,ESD GO:0016651 oxidoreductase activity, acting on NAD(P)H 0.981426108368698 -0.0187485524921974 106 5 0.00297619047619048 1680 17224 8564,51700,4846,114112,4714 KMO,CYB5R2,NOS3,TXNRD3,NDUFB8 GO:0008137 NADH dehydrogenase (ubiquinone) activity 0.981815577374497 -0.0183517913458379 39 1 0.000595238095238095 1680 17224 4714 NDUFB8 GO:0015932 nucleobase-containing compound transmembrane transporter activity 0.981815577374497 -0.0183517913458379 39 1 0.000595238095238095 1680 17224 54847 SIDT1 GO:0050136 NADH dehydrogenase (quinone) activity 0.981815577374497 -0.0183517913458379 39 1 0.000595238095238095 1680 17224 4714 NDUFB8 GO:0015370 solute:sodium symporter activity 0.984076018973191 -0.0160521298598462 77 3 0.00178571428571429 1680 17224 55117,6536,6507 SLC6A15,SLC6A9,SLC1A3 GO:0051539 4 iron, 4 sulfur cluster binding 0.985197289477469 -0.0149133639804349 41 1 0.000595238095238095 1680 17224 48 ACO1 GO:0003954 NADH dehydrogenase activity 0.985197289477469 -0.0149133639804349 41 1 0.000595238095238095 1680 17224 4714 NDUFB8 GO:0008173 RNA methyltransferase activity 0.986834126823015 -0.0132533116020479 62 2 0.00119047619047619 1680 17224 1787,221078 TRDMT1,NSUN6 GO:0000993 RNA polymerase II core binding 0.987950416895867 -0.0121227678216644 43 1 0.000595238095238095 1680 17224 64754 SMYD3 GO:0051540 metal cluster binding 0.987955489607387 -0.0121176332537654 63 2 0.00119047619047619 1680 17224 18,48 ABAT,ACO1 GO:0051536 iron-sulfur cluster binding 0.987955489607387 -0.0121176332537654 63 2 0.00119047619047619 1680 17224 18,48 ABAT,ACO1 GO:0034062 5'-3' RNA polymerase activity 0.989128654462894 -0.0109308704174775 44 1 0.000595238095238095 1680 17224 7015 TERT GO:0004407 histone deacetylase activity 0.989128654462894 -0.0109308704174775 44 1 0.000595238095238095 1680 17224 138151 NACC2 GO:0097747 RNA polymerase activity 0.989128654462894 -0.0109308704174775 44 1 0.000595238095238095 1680 17224 7015 TERT GO:1901363 heterocyclic compound binding 0.990600961933976 -0.00944348776651306 6080 550 0.327380952380952 1680 17224 8563,55640,134353,51175,4869,1488,6777,1050,55651,9531,64376,1768,5911,25837,114821,5455,7080,317649,4212,4093,120892,4774,5577,1244,388507,5167,10781,540,226,56898,26137,2073,148252,144132,4208,51084,833,26524,1573,9748,219749,29899,2290,134266,10388,51187,400961,200558,85416,9760,80216,55137,85460,148979,6812,6228,25946,3156,4860,4651,6775,84159,100289635,2194,6875,10150,64506,55760,57494,6158,3239,387751,92170,29842,26052,9658,4430,5596,2870,114112,7098,8564,51121,379,5874,1767,4661,91807,2597,2617,5208,10360,579,107,7481,23682,1832,114991,2260,260425,953,90874,1628,3219,27314,23464,5324,54845,3843,875,5028,9586,5585,2047,51222,57060,168620,4646,678,2242,83666,54795,26873,51560,9693,205,23250,10399,57761,3399,64324,6136,10000,2775,7494,79858,138429,3098,129607,6474,493,3169,7178,1911,349565,10626,445,4857,8153,11328,6196,7881,8320,51166,2115,2023,346157,30818,6520,4139,468,10257,4779,1380,10538,9149,83439,11278,2081,201798,113146,148523,5287,1746,63973,58528,5563,7301,860,3958,219654,26040,65997,7762,7546,116835,158405,253461,56952,3480,23461,126070,2624,10846,222537,112,10970,5058,2264,11001,6920,9935,55437,84033,202559,197257,9261,26508,57666,79646,10736,5071,23543,55769,4916,23046,91351,1592,10247,149076,26468,140469,604,80820,22989,118738,6591,2735,6207,1491,7846,81550,29997,59336,48,7431,2444,64850,4088,5903,2633,5754,5413,55762,23462,8444,659,57144,338323,51655,56978,3046,93986,10209,23551,2963,7020,6446,687,5106,6850,490,9645,1112,389643,9516,81788,9941,22862,4255,283078,1879,2329,7761,133923,388558,745,6124,5083,56906,23095,9310,90,54847,10396,2625,5578,5881,16,117154,8428,7227,5891,11262,11123,2731,2649,130399,100271849,7145,192670,93,2770,57491,3131,10769,5603,11178,63920,11279,23051,4291,6334,1718,9569,29093,122622,26038,23521,2122,57143,4858,4609,5592,6720,375449,6154,100129654,11069,7468,8476,148156,29941,6713,162394,1717,64754,6296,2042,29984,282890,5013,115207,1147,26010,780,7373,152485,10290,440,55603,220929,5462,5144,871,1787,5163,51700,11166,53354,5588,23314,467,474,481,57205,6622,3669,7552,3363,252884,22806,64208,6999,5579,619279,84451,3248,688,657,5602,4306,29942,84321,6224,4642,4601,10079,51191,3800,402,84525,10265,348751,2334,23678,5593,85007,79659,79603,8531,55964,4091,2672,5210,217,64283,6144,2977,148206,3198,7545,643836,1051,2268,7015,7703,79705,23367,1649,478,2180,4598,50865,3798,7358,3512,18,54033,22807,51303,10382,1595,29841,9465,1750,54805,2051,5159,5567,1545,51062,10188,147929,10413,4919,10110,157,203,10827,10891,84706,64919,55034,55893,11149,9886,122953,284716,285440,26227,6304,50862,6940,1938,6205,57593,56033,1052,23361,4846,30062,3048,23433,639,5325,3099,11031,26257,64764,152110,11022,255877,821,221833,79149,83852,83694,25925,92,2272,4233,5452,10794,3306,93349,2241,26136,4597,79739,7453,55509,27010,53335,148266,81931,9242,60468,348093,54937,113612,22983,23043,5966,54622,221078,6756,10644,58495,6164,4825,8614,30845,5580,59,22800,55033,5939,5865,4487,10765,3174,2104,3164,55753,116986,4141,23414,79834,9811,473,170691,138151,390,5608,55605,6206,2669,51776,9619 THOC5,FLVCR2,LSM11,TUBE1,NPM1,CTBP2,STAT5B,CEBPA,NHP2,BAG3,IKZF5,DNAH6,RAP2A,RAB26,ZBED9,POU3F3,NKX2-1,EIF4E3,MEIS2,SMAD9,LRRK2,NFIA,PRKAR2B,ABCC2,ZNF788P,ENPP1,ZNF266,ATP7B,ALDOA,BDH2,ZBTB20,ERCC5,DIRAS1,DNHD1,MEF2C,CRYL1,CARS,LATS2,CYP2J2,SLK,ZNF25,GPSM2,FOXG1,GRPEL2,SYCP2,RSL24D1,PAIP2B,APLF,ZIC5,TOX,ALPK1,FIGN,ZNF518B,GLIS1,STXBP1,RPS23,ZNF385A,HMGCR,PNP,MYO10,STAT4,ARID5B,ZNF605,FASN,TAF4B,MBNL2,CPEB1,DHX32,RIMKLB,RPL28,HOXD13,GVINP1,MTG1,TFCP2L1,DNM3,ZNF516,MYO1B,MAPK4,GRK6,TXNRD3,TLR3,KMO,RPL26L1,ARL4D,RAB27B,DNAH5,MYT1,MYLK3,GAPDH,GARS,PFKFB2,NPM3,NKX3-2,ADCY1,WNT11,RAB38,DSP,ZNF618,FGFR1,MAGI3,ENTPD1,ZNF697,DBP,HOXB9,RAB30,GCAT,PLAG1,ESRP1,IPO5,CBS,P2RY1,CREB5,PKN1,EPHB1,ZNF219,PCBP4,BHLHA15,MYO6,ZFP36L2,FES,PARP9,TRPM4,OPLAH,RAB6B,RAPGEF2,AK4,ATP11A,RACK1,TRIB3,ID3,NSD1,RPL12,AKT3,GNAO1,XBP1,NEK11,PIP5KL1,HK1,CMPK2,SHOX2,ATP2B4,FOXA1,TPT1,PHC1,NMNAT3,TRIM16,ASS1,NOVA1,RND2,FKBP9,RPS6KA2,KCNAB1,EOMES,AADAT,ETV1,ENO1,ZNF391,KCNIP3,SLC3A2,MARK1,ATF4,ABCC4,NFE2L1,CR2,BATF,DYRK1B,TCF7L1,KLF12,ERN1,TIGD4,AHNAK2,CIART,PIK3C2B,DLX2,NEUROG2,RRAGD,PRKAA2,TYRO3,RUNX2,LGALS3,ZCCHC24,SETBP1,RASL11B,ZNF215,ZIC2,HSPA12B,KIAA1958,ZBTB38,PRTFDC1,IGF1R,ABCA5,ZNF440,GATA2,PDE10A,HS3ST5,ADCY6,CKAP4,PAK1,FGFR4,SLC27A2,TCEA3,MAFB,STRADB,OBSCN,KHDRBS2,LDHD,MAPKAPK2,HEYL,FBRSL1,PANK3,SIX2,PRKN,RBFOX2,ZNF83,NTRK3,KIF21B,DDX60L,CYP26A1,RIDA,ZNF362,LHX6,MYO3B,BCL6,EEPD1,MYH15,ZNF488,SNAI2,GLI1,RPS13,CTH,TUBA1A,TDRD3,NOP53,PRDM13,ACO1,VIM,FRK,ETNPPL,SMAD3,RANBP2,GBP1,PTK7,SEPT5,ZNF701,HEY1,DYRK3,BMPR2,PAK5,NLRP14,RASD1,PRDM8,HBE1,FOXP2,EIF1,RASD2,GTF2F2,TFAP2A,SGK1,KLF9,PCK2,SYK,ATP2B1,MICAL2,FOXN3,NUGGC,LITAF,NUAK2,EXOG,FNDC3A,MGMT,MKX,EBF1,FMO4,ZNF214,ZNF474,ZNF808,MYRF,RPL4,PAX9,THAP10,KIF1B,ZNF235,ACVR1,SIDT1,ATP8A1,GATA3,PRKCA,RAC3,AARS,DACH2,STK24,TRPS1,MOK,SP140,RCAN3,GLDC,NR6A1,ACVR1C,MEF2B,TNS1,AGO4,ACVR2B,GNAI1,AHRR,HLF,PLK2,MAPK13,LZTS1,ZBED8,KLF8,ZHX3,MLF1,SCN8A,DHCR24,GTF2IRD1,MRPL22,ADSSL1,CHD5,RPL13A,MECOM,ADCK1,NOVA2,MYC,PRKG1,SREBF1,MAST4,RPL26,TCF24,RAPGEF4,NSD2,CDC42BPA,ZNF558,PKN3,SQLE,SLFN5,DHCR7,SMYD3,ACSM3,EPHA3,RHOD,ZNF311,OTX1,KCTD12,CHUK,SPATS2L,DDR1,COL14A1,ZNF827,SPEG,ASNS,TENT5A,ZNF438,POU5F1B,PDE4D,SERPINH1,TRDMT1,PDK1,CYB5R2,SOX21,PANK1,PRKCQ,SATB2,ATF3,ATOH1,ATP1B1,ATP10D,SNCA,ISG20,ZNF711,HTR7,ZNF396,IKZF3,POPDC3,TDO2,PRKCB,ZNF704,MAP3K21,HPGD,KLF5,BMPR1A,MAPK10,NR3C2,PURG,THOC3,RPS20,MYO1D,MXI1,ATP9A,HERC5,KIF5C,ARL2,HOPX,IRX5,FTCDNL1,AFF2,SGK3,PRKG2,PHYKPL,DYNC2H1,CERS4,YBX3,SEPT3,SMAD6,GFI1,PFKFB4,ALDH2,ARHGEF28,RPL21,GUCY1A2,ZNF714,HOXA1,ZIC1,ZFP62,CEBPB,FGR,TERT,PCGF2,LRRK1,LARP1,DDIT3,ATP1A3,ACSL1,MVK,HEBP1,KIF5A,UGDH,JCHAIN,ABAT,RBM11,IKZF2,FKBP11,TUBB4A,CYP51A1,GRHL1,AKAP7,DLX6,CNNM2,EPHB6,PDGFRB,PRKACB,CYP1B1,ATL1,TNK2,ZNF565,YAP1,ROR1,SGK2,GRK3,AK1,FAM114A2,PPARGC1A,GPT2,BCL11B,MOCOS,ZNF395,BVES,RHOBTB1,JDP2,RIMKLA,CYP4V2,PHGDH,SATB1,RNF141,ZNF354A,EEF2,RPS11,EBF4,BARX1,CEBPD,ZNF629,NOS3,RAX,HBG2,RHOQ,PRDM1,PLAGL1,HK2,RAB31,NKX2-8,CREB3L2,NEK10,TDRKH,BCL6B,CANX,SP8,ZSCAN5A,SETDB2,RPS6KL1,ZNF521,ACVR2A,FHIT,MET,POU2F2,ZNF460,HSPA2,SP140L,FER,TES,MVD,TTLL7,WARS,BATF3,TPK1,BCL11A,ZNF569,ZNF93,MSC,BACH2,RBPMS2,SOHLH2,CYP2U1,MAST1,TNIK,REL,ARL15,NSUN6,SSX1,IGF2BP2,OVOL2,RPL34,NKX6-1,STC2,EHD3,PRKCD,ACTA2,RRAS2,FKBP14,RBMS2,RAB3B,MSX1,KDM5B,HNF4G,ESRRG,NR4A1,OGDHL,AGAP2,MARS,ZFPM2,PEAK1,CTIF,RERE,ADAMTS17,NACC2,RND3,MAP2K6,KIF21A,RPS12,GEM,MAP3K20,ABCG1 GO:0004175 endopeptidase activity 0.9909963002226 -0.00904447803691818 409 27 0.0160714285714286 1680 17224 25801,9099,6768,8492,23621,720,726,11174,715,2161,84749,10584,2152,170691,4324,89782,25825,9508,360200,1515,649,3082,4325,4311,5046,7093,5125 GCA,USP2,ST14,PRSS12,BACE1,C4A,CAPN5,ADAMTS6,C1R,F12,USP30,COLEC10,F3,ADAMTS17,MMP15,LMLN,BACE2,ADAMTS3,TMPRSS9,CTSV,BMP1,HGF,MMP16,MME,PCSK6,TLL2,PCSK5 GO:0033558 protein deacetylase activity 0.991150929859175 -0.00888845568444974 46 1 0.000595238095238095 1680 17224 138151 NACC2 GO:0097159 organic cyclic compound binding 0.993263667236685 -0.00675912426462044 6166 556 0.330952380952381 1680 17224 8563,55640,134353,51175,4869,1488,6777,1050,55651,9531,64376,1768,5911,25837,114821,5455,7080,317649,4212,4093,120892,4774,5577,1244,388507,5167,10781,540,226,56898,153,26137,2073,148252,144132,4208,51084,833,26524,1573,9748,219749,29899,2290,134266,10388,51187,400961,200558,85416,9760,80216,55137,85460,148979,6812,6228,25946,3156,4860,4651,6775,84159,100289635,2194,6262,6875,10150,64506,55760,57494,6158,3239,387751,92170,29842,26052,9658,4430,5596,2870,114112,7098,8564,51121,379,5874,1767,4661,91807,2597,2617,5208,10360,579,107,7481,23682,1832,114991,2260,260425,953,90874,1628,3219,27314,23464,5324,54845,3843,875,5028,9586,5585,2047,51222,57060,168620,4646,678,2242,83666,54795,26873,51560,9693,205,23250,10399,57761,3399,64324,6136,10000,2775,114879,7494,79858,138429,3098,129607,6474,493,3169,7178,1911,349565,10626,445,4857,8153,11328,6196,7881,8320,51166,2115,2023,346157,30818,6520,4139,468,10257,4779,1380,10538,9149,83439,11278,2081,201798,113146,148523,5287,1746,63973,58528,5563,7301,860,3958,219654,26040,65997,7762,7546,116835,158405,253461,56952,3480,23461,126070,2624,10846,222537,112,10970,5058,2264,11001,6920,9935,55437,84033,202559,197257,9261,26508,57666,79646,10736,5071,23543,55769,4916,23046,91351,1592,10247,149076,26468,140469,604,80820,22989,118738,6591,2735,6207,1491,7846,81550,29997,59336,48,7431,2444,64850,4088,5903,2633,5754,5413,55762,23462,8444,659,57144,338323,51655,56978,3046,93986,10209,23551,2963,7020,6446,687,5106,6850,490,9645,1112,389643,9516,81788,9941,22862,4255,283078,1879,2329,7761,133923,388558,745,6124,5083,56906,23095,9310,90,54847,10396,2625,5578,5881,16,117154,8428,7227,5891,11262,11123,2731,2649,130399,100271849,7145,192670,93,2770,57491,3131,10769,5603,11178,63920,11279,23051,4291,6334,1718,9569,29093,122622,26038,23521,2122,57143,4858,4609,5592,6720,375449,6154,100129654,11069,7468,8476,10577,148156,29941,6713,162394,1717,64754,6296,2042,29984,282890,5013,115207,1147,26010,780,7373,152485,10290,440,55603,220929,5462,134429,5144,871,1787,5163,51700,11166,53354,5588,23314,467,474,481,57205,6622,3669,7552,3363,252884,22806,64208,6999,5579,619279,84451,3248,688,657,5602,4306,29942,84321,6224,4642,4601,10079,51191,3800,402,84525,10265,348751,8435,2334,23678,5593,85007,79659,79603,8531,55964,4091,2672,5210,217,64283,6144,2977,148206,3198,7545,643836,1051,2268,7015,7703,79705,23367,1649,478,2180,4598,50865,3798,7358,3512,18,54033,22807,51303,10382,1595,29841,9465,1750,54805,2051,5159,5567,1545,51062,10188,147929,10413,4919,10110,157,203,10827,10891,84706,64919,55034,55893,11149,9886,122953,284716,285440,26227,6304,50862,1938,6940,6205,57593,56033,1052,23361,4846,30062,3048,23433,639,5325,3099,11031,26257,64764,152110,11022,255877,821,221833,79149,83852,83694,25925,92,2272,4233,5452,10794,3306,93349,2241,26136,4597,79739,7453,55509,27010,53335,148266,81931,9242,60468,348093,54937,113612,22983,23043,5966,54622,221078,6756,10644,58495,6164,4825,5580,8614,30845,59,22800,55033,5939,5865,4487,10765,3174,2104,3164,55753,116986,4141,23414,79834,9811,473,170691,390,138151,5608,55605,6206,2669,51776,9619 THOC5,FLVCR2,LSM11,TUBE1,NPM1,CTBP2,STAT5B,CEBPA,NHP2,BAG3,IKZF5,DNAH6,RAP2A,RAB26,ZBED9,POU3F3,NKX2-1,EIF4E3,MEIS2,SMAD9,LRRK2,NFIA,PRKAR2B,ABCC2,ZNF788P,ENPP1,ZNF266,ATP7B,ALDOA,BDH2,ADRB1,ZBTB20,ERCC5,DIRAS1,DNHD1,MEF2C,CRYL1,CARS,LATS2,CYP2J2,SLK,ZNF25,GPSM2,FOXG1,GRPEL2,SYCP2,RSL24D1,PAIP2B,APLF,ZIC5,TOX,ALPK1,FIGN,ZNF518B,GLIS1,STXBP1,RPS23,ZNF385A,HMGCR,PNP,MYO10,STAT4,ARID5B,ZNF605,FASN,RYR2,TAF4B,MBNL2,CPEB1,DHX32,RIMKLB,RPL28,HOXD13,GVINP1,MTG1,TFCP2L1,DNM3,ZNF516,MYO1B,MAPK4,GRK6,TXNRD3,TLR3,KMO,RPL26L1,ARL4D,RAB27B,DNAH5,MYT1,MYLK3,GAPDH,GARS,PFKFB2,NPM3,NKX3-2,ADCY1,WNT11,RAB38,DSP,ZNF618,FGFR1,MAGI3,ENTPD1,ZNF697,DBP,HOXB9,RAB30,GCAT,PLAG1,ESRP1,IPO5,CBS,P2RY1,CREB5,PKN1,EPHB1,ZNF219,PCBP4,BHLHA15,MYO6,ZFP36L2,FES,PARP9,TRPM4,OPLAH,RAB6B,RAPGEF2,AK4,ATP11A,RACK1,TRIB3,ID3,NSD1,RPL12,AKT3,GNAO1,OSBPL5,XBP1,NEK11,PIP5KL1,HK1,CMPK2,SHOX2,ATP2B4,FOXA1,TPT1,PHC1,NMNAT3,TRIM16,ASS1,NOVA1,RND2,FKBP9,RPS6KA2,KCNAB1,EOMES,AADAT,ETV1,ENO1,ZNF391,KCNIP3,SLC3A2,MARK1,ATF4,ABCC4,NFE2L1,CR2,BATF,DYRK1B,TCF7L1,KLF12,ERN1,TIGD4,AHNAK2,CIART,PIK3C2B,DLX2,NEUROG2,RRAGD,PRKAA2,TYRO3,RUNX2,LGALS3,ZCCHC24,SETBP1,RASL11B,ZNF215,ZIC2,HSPA12B,KIAA1958,ZBTB38,PRTFDC1,IGF1R,ABCA5,ZNF440,GATA2,PDE10A,HS3ST5,ADCY6,CKAP4,PAK1,FGFR4,SLC27A2,TCEA3,MAFB,STRADB,OBSCN,KHDRBS2,LDHD,MAPKAPK2,HEYL,FBRSL1,PANK3,SIX2,PRKN,RBFOX2,ZNF83,NTRK3,KIF21B,DDX60L,CYP26A1,RIDA,ZNF362,LHX6,MYO3B,BCL6,EEPD1,MYH15,ZNF488,SNAI2,GLI1,RPS13,CTH,TUBA1A,TDRD3,NOP53,PRDM13,ACO1,VIM,FRK,ETNPPL,SMAD3,RANBP2,GBP1,PTK7,SEPT5,ZNF701,HEY1,DYRK3,BMPR2,PAK5,NLRP14,RASD1,PRDM8,HBE1,FOXP2,EIF1,RASD2,GTF2F2,TFAP2A,SGK1,KLF9,PCK2,SYK,ATP2B1,MICAL2,FOXN3,NUGGC,LITAF,NUAK2,EXOG,FNDC3A,MGMT,MKX,EBF1,FMO4,ZNF214,ZNF474,ZNF808,MYRF,RPL4,PAX9,THAP10,KIF1B,ZNF235,ACVR1,SIDT1,ATP8A1,GATA3,PRKCA,RAC3,AARS,DACH2,STK24,TRPS1,MOK,SP140,RCAN3,GLDC,NR6A1,ACVR1C,MEF2B,TNS1,AGO4,ACVR2B,GNAI1,AHRR,HLF,PLK2,MAPK13,LZTS1,ZBED8,KLF8,ZHX3,MLF1,SCN8A,DHCR24,GTF2IRD1,MRPL22,ADSSL1,CHD5,RPL13A,MECOM,ADCK1,NOVA2,MYC,PRKG1,SREBF1,MAST4,RPL26,TCF24,RAPGEF4,NSD2,CDC42BPA,NPC2,ZNF558,PKN3,SQLE,SLFN5,DHCR7,SMYD3,ACSM3,EPHA3,RHOD,ZNF311,OTX1,KCTD12,CHUK,SPATS2L,DDR1,COL14A1,ZNF827,SPEG,ASNS,TENT5A,ZNF438,POU5F1B,STARD4,PDE4D,SERPINH1,TRDMT1,PDK1,CYB5R2,SOX21,PANK1,PRKCQ,SATB2,ATF3,ATOH1,ATP1B1,ATP10D,SNCA,ISG20,ZNF711,HTR7,ZNF396,IKZF3,POPDC3,TDO2,PRKCB,ZNF704,MAP3K21,HPGD,KLF5,BMPR1A,MAPK10,NR3C2,PURG,THOC3,RPS20,MYO1D,MXI1,ATP9A,HERC5,KIF5C,ARL2,HOPX,IRX5,FTCDNL1,SOAT2,AFF2,SGK3,PRKG2,PHYKPL,DYNC2H1,CERS4,YBX3,SEPT3,SMAD6,GFI1,PFKFB4,ALDH2,ARHGEF28,RPL21,GUCY1A2,ZNF714,HOXA1,ZIC1,ZFP62,CEBPB,FGR,TERT,PCGF2,LRRK1,LARP1,DDIT3,ATP1A3,ACSL1,MVK,HEBP1,KIF5A,UGDH,JCHAIN,ABAT,RBM11,IKZF2,FKBP11,TUBB4A,CYP51A1,GRHL1,AKAP7,DLX6,CNNM2,EPHB6,PDGFRB,PRKACB,CYP1B1,ATL1,TNK2,ZNF565,YAP1,ROR1,SGK2,GRK3,AK1,FAM114A2,PPARGC1A,GPT2,BCL11B,MOCOS,ZNF395,BVES,RHOBTB1,JDP2,RIMKLA,CYP4V2,PHGDH,SATB1,RNF141,EEF2,ZNF354A,RPS11,EBF4,BARX1,CEBPD,ZNF629,NOS3,RAX,HBG2,RHOQ,PRDM1,PLAGL1,HK2,RAB31,NKX2-8,CREB3L2,NEK10,TDRKH,BCL6B,CANX,SP8,ZSCAN5A,SETDB2,RPS6KL1,ZNF521,ACVR2A,FHIT,MET,POU2F2,ZNF460,HSPA2,SP140L,FER,TES,MVD,TTLL7,WARS,BATF3,TPK1,BCL11A,ZNF569,ZNF93,MSC,BACH2,RBPMS2,SOHLH2,CYP2U1,MAST1,TNIK,REL,ARL15,NSUN6,SSX1,IGF2BP2,OVOL2,RPL34,NKX6-1,PRKCD,STC2,EHD3,ACTA2,RRAS2,FKBP14,RBMS2,RAB3B,MSX1,KDM5B,HNF4G,ESRRG,NR4A1,OGDHL,AGAP2,MARS,ZFPM2,PEAK1,CTIF,RERE,ADAMTS17,RND3,NACC2,MAP2K6,KIF21A,RPS12,GEM,MAP3K20,ABCG1 GO:0008009 chemokine activity 0.993501717483878 -0.00651948827119764 49 1 0.000595238095238095 1680 17224 3627 CXCL10 GO:0016796 exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 0.994710854445419 -0.00530318260280165 51 1 0.000595238095238095 1680 17224 3669 ISG20 GO:0043175 RNA polymerase core enzyme binding 0.994710854445419 -0.00530318260280165 51 1 0.000595238095238095 1680 17224 64754 SMYD3 GO:0016655 oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor 0.995695115787034 -0.00431417690591024 53 1 0.000595238095238095 1680 17224 4714 NDUFB8 GO:0008528 G-protein coupled peptide receptor activity 0.997150091365411 -0.00285397735636438 132 5 0.00297619047619048 1680 17224 643,2861,10203,5021,7253 CXCR5,GPR37,CALCRL,OXTR,TSHR GO:0003677 DNA binding 0.997204708661389 -0.00279920546122193 2489 206 0.122619047619048 1680 17224 10626,3512,2625,4869,6777,1050,22807,117154,7227,64376,8320,29841,1750,11262,2115,2023,114821,5455,346157,7080,30818,4212,468,4093,2649,4774,147929,4779,10413,1380,100271849,10538,57491,83439,10781,3131,11278,201798,26137,148523,2073,1746,10891,63973,63920,11178,4208,64919,11279,860,55893,23051,4291,219749,122953,9569,26040,7762,7546,6304,2290,26038,2122,50862,10388,158405,253461,6940,2624,126070,4609,85416,6720,57593,9760,85460,148979,56033,1052,25946,23361,30062,6775,100129654,84159,100289635,6920,7468,9935,639,6875,148156,5325,26508,3239,26257,64754,10736,64764,29842,5071,9658,282890,5013,55769,255877,221833,79149,149076,152485,220929,83852,5462,26468,604,80820,25925,5452,118738,10794,4661,93349,6591,2735,11166,59336,579,7481,23314,467,474,114991,148266,6622,55509,53335,7552,252884,4088,9242,81931,22806,60468,90874,619279,54937,688,1628,3219,4306,29942,55762,23462,4601,5966,5324,56978,9586,58495,51222,84525,4825,93986,10265,168620,2334,57060,2963,7020,687,79603,8531,2672,4091,678,4487,10765,3174,1112,2104,3164,9516,23414,148206,3198,4255,7545,473,283078,1879,1051,64324,138151,7015,7761,7494,7703,388558,745,5083,56906,6474,1649,3169,9310,1911 TRIM16,JCHAIN,GATA3,NPM1,STAT5B,CEBPA,IKZF2,DACH2,TRPS1,IKZF5,EOMES,GRHL1,DLX6,SP140,ETV1,ENO1,ZBED9,POU3F3,ZNF391,NKX2-1,KCNIP3,MEIS2,ATF4,SMAD9,NR6A1,NFIA,ZNF565,NFE2L1,YAP1,CR2,MEF2B,BATF,AHRR,TCF7L1,ZNF266,HLF,KLF12,TIGD4,ZBTB20,CIART,ERCC5,DLX2,PPARGC1A,NEUROG2,ZBED8,LZTS1,MEF2C,BCL11B,KLF8,RUNX2,ZNF395,ZHX3,MLF1,ZNF25,JDP2,GTF2IRD1,SETBP1,ZNF215,ZIC2,SATB1,FOXG1,CHD5,MECOM,RNF141,SYCP2,KIAA1958,ZBTB38,ZNF354A,GATA2,ZNF440,MYC,ZIC5,SREBF1,EBF4,TOX,ZNF518B,GLIS1,BARX1,CEBPD,ZNF385A,ZNF629,RAX,STAT4,TCF24,ARID5B,ZNF605,TCEA3,NSD2,MAFB,PRDM1,TAF4B,ZNF558,PLAGL1,HEYL,HOXD13,NKX2-8,SMYD3,SIX2,CREB3L2,TFCP2L1,PRKN,ZNF516,ZNF311,OTX1,ZNF83,BCL6B,SP8,ZSCAN5A,ZNF362,ZNF827,ZNF438,SETDB2,POU5F1B,LHX6,BCL6,EEPD1,ZNF521,POU2F2,ZNF488,ZNF460,MYT1,SP140L,SNAI2,GLI1,SOX21,PRDM13,NKX3-2,WNT11,SATB2,ATF3,ATOH1,ZNF618,ZNF569,SNCA,BATF3,BCL11A,ZNF711,ZNF396,SMAD3,MSC,ZNF93,IKZF3,BACH2,ZNF697,ZNF704,SOHLH2,KLF5,DBP,HOXB9,NR3C2,PURG,ZNF701,HEY1,MXI1,REL,PLAG1,PRDM8,CREB5,OVOL2,ZNF219,HOPX,NKX6-1,FOXP2,IRX5,BHLHA15,AFF2,PCBP4,GTF2F2,TFAP2A,KLF9,CERS4,YBX3,GFI1,SMAD6,ZFP36L2,MSX1,KDM5B,HNF4G,FOXN3,ESRRG,NR4A1,LITAF,ZFPM2,ZNF714,HOXA1,MGMT,ZIC1,RERE,MKX,EBF1,CEBPB,NSD1,NACC2,TERT,ZNF214,XBP1,PCGF2,ZNF808,MYRF,PAX9,THAP10,SHOX2,DDIT3,FOXA1,ZNF235,PHC1 GO:0001653 peptide receptor activity 0.997356403089312 -0.00264709738358792 133 5 0.00297619047619048 1680 17224 643,2861,10203,5021,7253 CXCR5,GPR37,CALCRL,OXTR,TSHR GO:0001098 basal transcription machinery binding 0.997427511927631 -0.00257580260542824 58 1 0.000595238095238095 1680 17224 64754 SMYD3 GO:0001099 basal RNA polymerase II transcription machinery binding 0.997427511927631 -0.00257580260542824 58 1 0.000595238095238095 1680 17224 64754 SMYD3 GO:0043021 ribonucleoprotein complex binding 0.997683457946938 -0.00231922938762175 118 4 0.00238095238095238 1680 17224 4869,10399,1938,64506 NPM1,RACK1,EEF2,CPEB1 GO:0004518 nuclease activity 0.997784311473618 -0.002218146796049 212 10 0.00595238095238095 1680 17224 5167,10247,200558,2081,2073,79008,9941,80055,79605,3669 ENPP1,RIDA,APLF,ERN1,ERCC5,SLX1B,EXOG,PGAP1,PGBD5,ISG20 GO:0016779 nucleotidyltransferase activity 0.998046550055811 -0.00195536041594418 137 5 0.00297619047619048 1680 17224 349565,55603,7015,54855,1040 NMNAT3,TENT5A,TERT,TENT5C,CDS1 GO:0101005 ubiquitinyl hydrolase activity 0.998177701313535 -0.00182396109262386 121 4 0.00238095238095238 1680 17224 220213,9099,7347,84749 OTUD1,USP2,UCHL3,USP30 GO:0036459 thiol-dependent ubiquitinyl hydrolase activity 0.998177701313535 -0.00182396109262386 121 4 0.00238095238095238 1680 17224 220213,9099,84749,7347 OTUD1,USP2,USP30,UCHL3 GO:0016407 acetyltransferase activity 0.998445085773976 -0.00155612435974802 105 3 0.00178571428571429 1680 17224 23464,54947,2194 GCAT,LPCAT2,FASN GO:0042379 chemokine receptor binding 0.998462990142969 -0.00153819226842219 63 1 0.000595238095238095 1680 17224 3627 CXCL10 GO:0003697 single-stranded DNA binding 0.998572912385523 -0.00142810687383658 106 3 0.00178571428571429 1680 17224 3512,2073,8531 JCHAIN,ERCC5,YBX3 GO:0004540 ribonuclease activity 0.998897740697637 -0.00110286723692364 109 3 0.00178571428571429 1680 17224 10247,2081,3669 RIDA,ERN1,ISG20 GO:0004004 ATP-dependent RNA helicase activity 0.998982145148702 -0.00101837321732418 67 1 0.000595238095238095 1680 17224 55760 DHX32 GO:0003724 RNA helicase activity 0.999081812687753 -0.000918609104426585 68 1 0.000595238095238095 1680 17224 55760 DHX32 GO:0008186 RNA-dependent ATPase activity 0.999081812687753 -0.000918609104426585 68 1 0.000595238095238095 1680 17224 55760 DHX32 GO:0008233 peptidase activity 0.999108522962239 -0.00089187463973492 639 41 0.0244047619047619 1680 17224 10279,6768,8492,23621,720,11174,84749,10584,9372,2152,220213,54504,25825,9805,119587,1363,5046,57628,25801,9099,79875,726,27351,715,2161,7347,254042,4324,170691,89782,9508,5547,360200,1515,649,3082,745,4325,4311,7093,5125 PRSS16,ST14,PRSS12,BACE1,C4A,ADAMTS6,USP30,COLEC10,ZFYVE9,F3,OTUD1,CPVL,BACE2,SCRN1,CPXM2,CPE,PCSK6,DPP10,GCA,USP2,THSD4,CAPN5,DESI1,C1R,F12,UCHL3,METAP1D,MMP15,ADAMTS17,LMLN,ADAMTS3,PRCP,TMPRSS9,CTSV,BMP1,HGF,MYRF,MMP16,MME,TLL2,PCSK5 GO:0019783 ubiquitin-like protein-specific protease activity 0.99912125079363 -0.000879135532793268 130 4 0.00238095238095238 1680 17224 220213,9099,84749,7347 OTUD1,USP2,USP30,UCHL3 GO:0070011 peptidase activity, acting on L-amino acid peptides 0.999485593676733 -0.000514538675590647 614 38 0.0226190476190476 1680 17224 10279,6768,8492,23621,720,11174,84749,10584,9372,2152,220213,54504,25825,9805,119587,1363,5046,57628,25801,9099,726,715,2161,7347,254042,4324,170691,89782,9508,5547,360200,1515,649,3082,4325,4311,7093,5125 PRSS16,ST14,PRSS12,BACE1,C4A,ADAMTS6,USP30,COLEC10,ZFYVE9,F3,OTUD1,CPVL,BACE2,SCRN1,CPXM2,CPE,PCSK6,DPP10,GCA,USP2,CAPN5,C1R,F12,UCHL3,METAP1D,MMP15,ADAMTS17,LMLN,ADAMTS3,PRCP,TMPRSS9,CTSV,BMP1,HGF,MMP16,MME,TLL2,PCSK5 GO:0016410 N-acyltransferase activity 0.999697061713111 -0.000302984181960761 103 2 0.00119047619047619 1680 17224 79603,10715 CERS4,CERS1 GO:0008234 cysteine-type peptidase activity 0.999761292405833 -0.0002387360893592 198 7 0.00416666666666667 1680 17224 25801,220213,9099,84749,7347,1515,726 GCA,OTUD1,USP2,USP30,UCHL3,CTSV,CAPN5 GO:0004386 helicase activity 0.999881549898092 -0.000118457117674882 154 4 0.00238095238095238 1680 17224 26038,91351,2963,55760 CHD5,DDX60L,GTF2F2,DHX32 GO:0140097 catalytic activity, acting on DNA 0.999904849875592 -9.51546514678141e-05 193 6 0.00357142857142857 1680 17224 2073,79008,7015,200558,4255,3669 ERCC5,SLX1B,TERT,APLF,MGMT,ISG20 GO:0008026 ATP-dependent helicase activity 0.999953883958034 -4.61171053431339e-05 97 1 0.000595238095238095 1680 17224 55760 DHX32 GO:0070035 purine NTP-dependent helicase activity 0.999953883958034 -4.61171053431339e-05 97 1 0.000595238095238095 1680 17224 55760 DHX32 GO:0003729 mRNA binding 0.999997488190301 -2.51181285341579e-06 406 16 0.00952380952380952 1680 17224 6154,8563,23543,54845,48,10644,4857,23521,64506,348093,57060,8531,678,23367,25946,6207 RPL26,THOC5,RBFOX2,ESRP1,ACO1,IGF2BP2,NOVA1,RPL13A,CPEB1,RBPMS2,PCBP4,YBX3,ZFP36L2,LARP1,ZNF385A,RPS13 GO:0004930 G-protein coupled receptor activity 0.999999743771029 -2.5622900427343e-07 819 42 0.025 1680 17224 643,282763,81491,9170,6785,55366,9620,1951,8477,8325,79339,5028,51222,57211,576,2838,23596,22859,343171,7253,5159,23432,1131,8321,11245,8322,10203,390442,2842,25987,285601,2861,3363,391195,51704,577,26996,153,3248,5021,166647,23266 CXCR5,OR51B5,GPR63,LPAR2,ELOVL4,LGR4,CELSR1,CELSR3,GPR65,FZD8,OR51B4,P2RY1,ZNF219,ADGRG6,ADGRB2,GPR15,OPN3,ADGRL1,OR2W3,TSHR,PDGFRB,GPR161,CHRM3,FZD1,GPR176,FZD4,CALCRL,OR11H4,GPR19,TSKU,GPR150,GPR37,HTR7,OR2T33,GPRC5B,ADGRB3,GPR160,ADRB1,HPGD,OXTR,ADGRA3,ADGRL2 GO:0140098 catalytic activity, acting on RNA 0.999999760660266 -2.39339762328862e-07 374 12 0.00714285714285714 1680 17224 833,1787,10247,2617,7015,2081,221078,4141,16,3669,55760,7453 CARS,TRDMT1,RIDA,GARS,TERT,ERN1,NSUN6,MARS,AARS,ISG20,DHX32,WARS GO:0003676 nucleic acid binding 0.999999999823188 -1.76811683536254e-10 4207 296 0.176190476190476 1680 17224 8563,54847,134353,2625,4869,6777,1050,55651,117154,16,7227,64376,11262,11123,114821,5455,7080,317649,4212,4093,2649,4774,100271849,192670,7145,388507,57491,5167,10781,3131,226,26137,2073,63920,11178,4208,833,11279,23051,4291,219749,29093,9569,2290,26038,23521,2122,10388,51187,4858,400961,4609,85416,6720,9760,85460,148979,6812,6228,25946,6154,6775,100129654,84159,100289635,2194,7468,6875,10150,148156,64506,55760,6158,3239,64754,29842,9658,282890,5013,115207,26010,7373,152485,7098,220929,55603,5462,51121,871,4661,1787,11166,10360,579,467,23314,7481,474,1832,114991,3669,6622,7552,252884,22806,90874,619279,688,1628,3219,4306,29942,84321,6224,4601,5324,54845,3843,51191,9586,51222,84525,10265,57060,2334,168620,79603,8531,2672,4091,678,64283,6144,10399,148206,3198,7545,1051,643836,64324,6136,7015,7494,7703,6474,1649,3169,23367,7178,1911,10626,3512,445,4857,22807,54033,8320,29841,1750,2023,2115,346157,30818,468,6520,4779,147929,10413,1380,10538,83439,11278,201798,113146,148523,1746,10891,63973,64919,860,3958,55893,219654,122953,26040,7546,7762,6304,50862,158405,253461,1938,6940,126070,2624,6205,57593,56033,1052,10970,23361,30062,6920,9935,639,202559,5325,26508,57666,26257,10736,64764,5071,23543,55769,11022,255877,821,91351,221833,79149,149076,10247,83852,26468,25925,80820,604,5452,118738,10794,6591,93349,6207,2735,29997,81550,26136,59336,48,7431,55509,53335,148266,4088,9242,81931,5903,60468,348093,54937,55762,23462,5966,221078,6756,56978,10644,58495,6164,4825,93986,30845,10209,2963,7020,687,5939,4487,10765,3174,1112,2104,3164,9516,4141,23414,22862,9941,4255,9811,283078,473,1879,170691,138151,7761,133923,388558,745,5083,6206,6124,56906,51776,9310 THOC5,SIDT1,LSM11,GATA3,NPM1,STAT5B,CEBPA,NHP2,DACH2,AARS,TRPS1,IKZF5,SP140,RCAN3,ZBED9,POU3F3,NKX2-1,EIF4E3,MEIS2,SMAD9,NR6A1,NFIA,MEF2B,AGO4,TNS1,ZNF788P,AHRR,ENPP1,ZNF266,HLF,ALDOA,ZBTB20,ERCC5,ZBED8,LZTS1,MEF2C,CARS,KLF8,ZHX3,MLF1,ZNF25,MRPL22,GTF2IRD1,FOXG1,CHD5,RPL13A,MECOM,SYCP2,RSL24D1,NOVA2,PAIP2B,MYC,ZIC5,SREBF1,TOX,ZNF518B,GLIS1,STXBP1,RPS23,ZNF385A,RPL26,STAT4,TCF24,ARID5B,ZNF605,FASN,NSD2,TAF4B,MBNL2,ZNF558,CPEB1,DHX32,RPL28,HOXD13,SMYD3,TFCP2L1,ZNF516,ZNF311,OTX1,KCTD12,SPATS2L,COL14A1,ZNF827,TLR3,ZNF438,TENT5A,POU5F1B,RPL26L1,SERPINH1,MYT1,TRDMT1,SOX21,NPM3,NKX3-2,ATF3,SATB2,WNT11,ATOH1,DSP,ZNF618,ISG20,SNCA,ZNF711,ZNF396,IKZF3,ZNF697,ZNF704,KLF5,DBP,HOXB9,NR3C2,PURG,THOC3,RPS20,MXI1,PLAG1,ESRP1,IPO5,HERC5,CREB5,ZNF219,HOPX,IRX5,PCBP4,AFF2,BHLHA15,CERS4,YBX3,GFI1,SMAD6,ZFP36L2,ARHGEF28,RPL21,RACK1,ZNF714,HOXA1,ZIC1,CEBPB,ZFP62,NSD1,RPL12,TERT,XBP1,PCGF2,SHOX2,DDIT3,FOXA1,LARP1,TPT1,PHC1,TRIM16,JCHAIN,ASS1,NOVA1,IKZF2,RBM11,EOMES,GRHL1,DLX6,ENO1,ETV1,ZNF391,KCNIP3,ATF4,SLC3A2,NFE2L1,ZNF565,YAP1,CR2,BATF,TCF7L1,KLF12,TIGD4,AHNAK2,CIART,DLX2,PPARGC1A,NEUROG2,BCL11B,RUNX2,LGALS3,ZNF395,ZCCHC24,JDP2,SETBP1,ZIC2,ZNF215,SATB1,RNF141,KIAA1958,ZBTB38,EEF2,ZNF354A,ZNF440,GATA2,RPS11,EBF4,BARX1,CEBPD,CKAP4,ZNF629,RAX,TCEA3,MAFB,PRDM1,KHDRBS2,PLAGL1,HEYL,FBRSL1,NKX2-8,SIX2,CREB3L2,PRKN,RBFOX2,ZNF83,TDRKH,BCL6B,CANX,DDX60L,SP8,ZSCAN5A,ZNF362,RIDA,SETDB2,LHX6,ZNF521,EEPD1,BCL6,POU2F2,ZNF488,ZNF460,SNAI2,SP140L,RPS13,GLI1,NOP53,TDRD3,TES,PRDM13,ACO1,VIM,BATF3,BCL11A,ZNF569,SMAD3,MSC,ZNF93,RANBP2,BACH2,RBPMS2,SOHLH2,ZNF701,HEY1,REL,NSUN6,SSX1,PRDM8,IGF2BP2,OVOL2,RPL34,NKX6-1,FOXP2,EHD3,EIF1,GTF2F2,TFAP2A,KLF9,RBMS2,MSX1,KDM5B,HNF4G,FOXN3,ESRRG,NR4A1,LITAF,MARS,ZFPM2,FNDC3A,EXOG,MGMT,CTIF,MKX,RERE,EBF1,ADAMTS17,NACC2,ZNF214,ZNF474,ZNF808,MYRF,PAX9,RPS12,RPL4,THAP10,MAP3K20,ZNF235 GO:0003723 RNA binding 0.999999999870906 -1.29093830808203e-10 1848 93 0.0553571428571429 1680 17224 8563,54847,23543,134353,445,4869,11022,115207,26010,55651,821,7373,54033,4857,91351,16,10247,7098,55603,51121,871,11123,2023,6207,1787,6520,317649,29997,81550,10360,26136,48,7431,192670,7145,1832,3669,4088,5903,348093,226,113146,1746,10891,29942,84321,6224,833,3958,54845,219654,3843,221078,29093,51191,10644,23521,6164,51187,1938,4858,6205,2334,57060,10209,8531,6812,678,6228,25946,5939,10970,6154,64283,6144,2194,4141,10399,22862,202559,10150,64506,55760,9811,6136,6158,7015,57666,6124,6206,51776,23367,7178 THOC5,SIDT1,RBFOX2,LSM11,ASS1,NPM1,TDRKH,KCTD12,SPATS2L,NHP2,CANX,COL14A1,RBM11,NOVA1,DDX60L,AARS,RIDA,TLR3,TENT5A,RPL26L1,SERPINH1,RCAN3,ENO1,RPS13,TRDMT1,SLC3A2,EIF4E3,NOP53,TDRD3,NPM3,TES,ACO1,VIM,AGO4,TNS1,DSP,ISG20,SMAD3,RANBP2,RBPMS2,ALDOA,AHNAK2,DLX2,PPARGC1A,PURG,THOC3,RPS20,CARS,LGALS3,ESRP1,ZCCHC24,IPO5,NSUN6,MRPL22,HERC5,IGF2BP2,RPL13A,RPL34,RSL24D1,EEF2,NOVA2,RPS11,AFF2,PCBP4,EIF1,YBX3,STXBP1,ZFP36L2,RPS23,ZNF385A,RBMS2,CKAP4,RPL26,ARHGEF28,RPL21,FASN,MARS,RACK1,FNDC3A,KHDRBS2,MBNL2,CPEB1,DHX32,CTIF,RPL12,RPL28,TERT,FBRSL1,RPL4,RPS12,MAP3K20,LARP1,TPT1 GO:0004984 olfactory receptor activity 0.999999999964556 -3.54444572088195e-11 379 5 0.00297619047619048 1680 17224 282763,79339,391195,390442,343171 OR51B5,OR51B4,OR2T33,OR11H4,OR2W3 GO:0015106 bicarbonate transmembrane transporter activity 0.999999999965234 -3.47660359816016e-11 23 0 0 1680 17224 GO:0042923 neuropeptide binding 0.999999999965234 -3.47660359816016e-11 23 0 0 1680 17224 GO:0004309 exopolyphosphatase activity 0.999999999966423 -3.35766284449078e-11 5 0 0 1680 17224 GO:0004844 uracil DNA N-glycosylase activity 0.999999999966423 -3.35766284449078e-11 5 0 0 1680 17224 GO:0050733 RS domain binding 0.999999999966423 -3.35766284449078e-11 5 0 0 1680 17224 GO:0031702 type 1 angiotensin receptor binding 0.999999999966423 -3.35766284449078e-11 5 0 0 1680 17224 GO:0004661 protein geranylgeranyltransferase activity 0.999999999966423 -3.35766284449078e-11 5 0 0 1680 17224 GO:0019808 polyamine binding 0.999999999966423 -3.35766284449078e-11 5 0 0 1680 17224 GO:0061665 SUMO ligase activity 0.999999999966423 -3.35766284449078e-11 5 0 0 1680 17224 GO:0030884 exogenous lipid antigen binding 0.999999999966423 -3.35766284449078e-11 5 0 0 1680 17224 GO:0043141 ATP-dependent 5'-3' DNA helicase activity 0.999999999966423 -3.35766284449078e-11 5 0 0 1680 17224 GO:0031727 CCR2 chemokine receptor binding 0.999999999966423 -3.35766284449078e-11 5 0 0 1680 17224 GO:0004090 carbonyl reductase (NADPH) activity 0.999999999966423 -3.35766284449078e-11 5 0 0 1680 17224 GO:0005502 11-cis retinal binding 0.999999999966423 -3.35766284449078e-11 5 0 0 1680 17224 GO:0051575 5'-deoxyribose-5-phosphate lyase activity 0.999999999966423 -3.35766284449078e-11 5 0 0 1680 17224 GO:0016454 C-palmitoyltransferase activity 0.999999999966423 -3.35766284449078e-11 5 0 0 1680 17224 GO:0070568 guanylyltransferase activity 0.999999999966423 -3.35766284449078e-11 5 0 0 1680 17224 GO:0016929 SUMO-specific protease activity 0.999999999966423 -3.35766284449078e-11 5 0 0 1680 17224 GO:0030883 endogenous lipid antigen binding 0.999999999966423 -3.35766284449078e-11 5 0 0 1680 17224 GO:0016721 oxidoreductase activity, acting on superoxide radicals as acceptor 0.999999999966423 -3.35766284449078e-11 5 0 0 1680 17224 GO:1990446 U1 snRNP binding 0.999999999966423 -3.35766284449078e-11 5 0 0 1680 17224 GO:0052811 1-phosphatidylinositol-3-phosphate 4-kinase activity 0.999999999966423 -3.35766284449078e-11 5 0 0 1680 17224 GO:0005143 interleukin-12 receptor binding 0.999999999966423 -3.35766284449078e-11 5 0 0 1680 17224 GO:0004749 ribose phosphate diphosphokinase activity 0.999999999966423 -3.35766284449078e-11 5 0 0 1680 17224 GO:0015616 DNA translocase activity 0.999999999966423 -3.35766284449078e-11 5 0 0 1680 17224 GO:0046923 ER retention sequence binding 0.999999999966423 -3.35766284449078e-11 5 0 0 1680 17224 GO:1990948 ubiquitin ligase inhibitor activity 0.999999999966423 -3.35766284449078e-11 5 0 0 1680 17224 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity 0.999999999966423 -3.35766284449078e-11 5 0 0 1680 17224 GO:0000828 inositol hexakisphosphate kinase activity 0.999999999966423 -3.35766284449078e-11 5 0 0 1680 17224 GO:0003923 GPI-anchor transamidase activity 0.999999999966423 -3.35766284449078e-11 5 0 0 1680 17224 GO:0004445 inositol-polyphosphate 5-phosphatase activity 0.999999999966423 -3.35766284449078e-11 5 0 0 1680 17224 GO:0004920 interleukin-10 receptor activity 0.999999999966423 -3.35766284449078e-11 5 0 0 1680 17224 GO:0103025 alpha-amylase activity (releasing maltohexaose) 0.999999999966423 -3.35766284449078e-11 5 0 0 1680 17224 GO:0004466 long-chain-acyl-CoA dehydrogenase activity 0.999999999966423 -3.35766284449078e-11 5 0 0 1680 17224 GO:0043515 kinetochore binding 0.999999999966423 -3.35766284449078e-11 5 0 0 1680 17224 GO:0000832 inositol hexakisphosphate 5-kinase activity 0.999999999966423 -3.35766284449078e-11 5 0 0 1680 17224 GO:0030882 lipid antigen binding 0.999999999966423 -3.35766284449078e-11 5 0 0 1680 17224 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity 0.999999999966423 -3.35766284449078e-11 5 0 0 1680 17224 GO:0071987 WD40-repeat domain binding 0.999999999966423 -3.35766284449078e-11 5 0 0 1680 17224 GO:0004459 L-lactate dehydrogenase activity 0.999999999966423 -3.35766284449078e-11 5 0 0 1680 17224 GO:0016933 extracellularly glycine-gated ion channel activity 0.999999999966423 -3.35766284449078e-11 5 0 0 1680 17224 GO:0004556 alpha-amylase activity 0.999999999966423 -3.35766284449078e-11 5 0 0 1680 17224 GO:0061676 importin-alpha family protein binding 0.999999999966423 -3.35766284449078e-11 5 0 0 1680 17224 GO:0103068 leukotriene C4 gamma-glutamyl transferase activity 0.999999999966423 -3.35766284449078e-11 5 0 0 1680 17224 GO:0000827 inositol-1,3,4,5,6-pentakisphosphate kinase activity 0.999999999966423 -3.35766284449078e-11 5 0 0 1680 17224 GO:0009378 four-way junction helicase activity 0.999999999966423 -3.35766284449078e-11 5 0 0 1680 17224 GO:0016934 extracellularly glycine-gated chloride channel activity 0.999999999966423 -3.35766284449078e-11 5 0 0 1680 17224 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity 0.999999999966423 -3.35766284449078e-11 5 0 0 1680 17224 GO:0016841 ammonia-lyase activity 0.999999999966423 -3.35766284449078e-11 5 0 0 1680 17224 GO:0052723 inositol hexakisphosphate 1-kinase activity 0.999999999966423 -3.35766284449078e-11 5 0 0 1680 17224 GO:0003847 1-alkyl-2-acetylglycerophosphocholine esterase activity 0.999999999966423 -3.35766284449078e-11 5 0 0 1680 17224 GO:0008273 calcium, potassium:sodium antiporter activity 0.999999999966423 -3.35766284449078e-11 5 0 0 1680 17224 GO:0035473 lipase binding 0.999999999966423 -3.35766284449078e-11 5 0 0 1680 17224 GO:0032552 deoxyribonucleotide binding 0.999999999966423 -3.35766284449078e-11 5 0 0 1680 17224 GO:0033192 calmodulin-dependent protein phosphatase activity 0.999999999966423 -3.35766284449078e-11 5 0 0 1680 17224 GO:0001537 N-acetylgalactosamine 4-O-sulfotransferase activity 0.999999999966423 -3.35766284449078e-11 5 0 0 1680 17224 GO:0004563 beta-N-acetylhexosaminidase activity 0.999999999966423 -3.35766284449078e-11 5 0 0 1680 17224 GO:0000702 oxidized base lesion DNA N-glycosylase activity 0.999999999966423 -3.35766284449078e-11 5 0 0 1680 17224 GO:0016019 peptidoglycan receptor activity 0.999999999966423 -3.35766284449078e-11 5 0 0 1680 17224 GO:0004784 superoxide dismutase activity 0.999999999966423 -3.35766284449078e-11 5 0 0 1680 17224 GO:0052724 inositol hexakisphosphate 3-kinase activity 0.999999999966423 -3.35766284449078e-11 5 0 0 1680 17224 GO:0000104 succinate dehydrogenase activity 0.999999999966423 -3.35766284449078e-11 5 0 0 1680 17224 GO:0098519 nucleotide phosphatase activity, acting on free nucleotides 0.999999999966423 -3.35766284449078e-11 5 0 0 1680 17224 GO:0004448 isocitrate dehydrogenase activity 0.999999999966423 -3.35766284449078e-11 5 0 0 1680 17224 GO:0004689 phosphorylase kinase activity 0.999999999966423 -3.35766284449078e-11 5 0 0 1680 17224 GO:0004849 uridine kinase activity 0.999999999966423 -3.35766284449078e-11 5 0 0 1680 17224 GO:0032407 MutSalpha complex binding 0.999999999966423 -3.35766284449078e-11 5 0 0 1680 17224 GO:0019103 pyrimidine nucleotide binding 0.999999999966423 -3.35766284449078e-11 5 0 0 1680 17224 GO:0001031 RNA polymerase III type 2 promoter DNA binding 0.999999999966423 -3.35766284449078e-11 5 0 0 1680 17224 GO:0004758 serine C-palmitoyltransferase activity 0.999999999966423 -3.35766284449078e-11 5 0 0 1680 17224 GO:0070122 isopeptidase activity 0.999999999966423 -3.35766284449078e-11 5 0 0 1680 17224 GO:0044388 small protein activating enzyme binding 0.999999999966423 -3.35766284449078e-11 5 0 0 1680 17224 GO:0031726 CCR1 chemokine receptor binding 0.999999999966423 -3.35766284449078e-11 5 0 0 1680 17224 GO:0015057 thrombin-activated receptor activity 0.999999999966423 -3.35766284449078e-11 5 0 0 1680 17224 GO:0097506 deaminated base DNA N-glycosylase activity 0.999999999966423 -3.35766284449078e-11 5 0 0 1680 17224 GO:0008379 thioredoxin peroxidase activity 0.999999999966423 -3.35766284449078e-11 5 0 0 1680 17224 GO:0030550 acetylcholine receptor inhibitor activity 0.999999999966423 -3.35766284449078e-11 5 0 0 1680 17224 GO:0044547 DNA topoisomerase binding 0.999999999966423 -3.35766284449078e-11 5 0 0 1680 17224 GO:0046976 histone methyltransferase activity (H3-K27 specific) 0.999999999966423 -3.35766284449078e-11 5 0 0 1680 17224 GO:0023029 MHC class Ib protein binding 0.999999999966423 -3.35766284449078e-11 5 0 0 1680 17224 GO:0004045 aminoacyl-tRNA hydrolase activity 0.999999999966423 -3.35766284449078e-11 5 0 0 1680 17224 GO:0004839 ubiquitin activating enzyme activity 0.999999999966423 -3.35766284449078e-11 5 0 0 1680 17224 GO:0051373 FATZ binding 0.999999999966423 -3.35766284449078e-11 5 0 0 1680 17224 GO:0030156 benzodiazepine receptor binding 0.999999999966423 -3.35766284449078e-11 5 0 0 1680 17224 GO:0015562 efflux transmembrane transporter activity 0.999999999966423 -3.35766284449078e-11 5 0 0 1680 17224 GO:0015333 peptide:proton symporter activity 0.999999999966423 -3.35766284449078e-11 5 0 0 1680 17224 GO:0032190 acrosin binding 0.999999999966423 -3.35766284449078e-11 5 0 0 1680 17224 GO:0032184 SUMO polymer binding 0.999999999966423 -3.35766284449078e-11 5 0 0 1680 17224 GO:0008048 calcium sensitive guanylate cyclase activator activity 0.999999999966423 -3.35766284449078e-11 5 0 0 1680 17224 GO:0080084 5S rDNA binding 0.999999999966423 -3.35766284449078e-11 5 0 0 1680 17224 GO:0019763 immunoglobulin receptor activity 0.999999999966423 -3.35766284449078e-11 5 0 0 1680 17224 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding 0.999999999966423 -3.35766284449078e-11 5 0 0 1680 17224 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding 0.999999999966423 -3.35766284449078e-11 5 0 0 1680 17224 GO:0015272 ATP-activated inward rectifier potassium channel activity 0.999999999966423 -3.35766284449078e-11 5 0 0 1680 17224 GO:0070883 pre-miRNA binding 0.999999999966423 -3.35766284449078e-11 5 0 0 1680 17224 GO:0008177 succinate dehydrogenase (ubiquinone) activity 0.999999999966423 -3.35766284449078e-11 5 0 0 1680 17224 GO:0048273 mitogen-activated protein kinase p38 binding 0.999999999966423 -3.35766284449078e-11 5 0 0 1680 17224 GO:0009374 biotin binding 0.999999999966423 -3.35766284449078e-11 5 0 0 1680 17224 GO:0015185 gamma-aminobutyric acid transmembrane transporter activity 0.999999999966423 -3.35766284449078e-11 5 0 0 1680 17224 GO:0004144 diacylglycerol O-acyltransferase activity 0.999999999966423 -3.35766284449078e-11 5 0 0 1680 17224 GO:0033592 RNA strand annealing activity 0.999999999966423 -3.35766284449078e-11 5 0 0 1680 17224 GO:0047631 ADP-ribose diphosphatase activity 0.999999999966423 -3.35766284449078e-11 5 0 0 1680 17224 GO:0004994 somatostatin receptor activity 0.999999999966423 -3.35766284449078e-11 5 0 0 1680 17224 GO:0005324 long-chain fatty acid transporter activity 0.999999999966423 -3.35766284449078e-11 5 0 0 1680 17224 GO:0030284 estrogen receptor activity 0.999999999966423 -3.35766284449078e-11 5 0 0 1680 17224 GO:0035727 lysophosphatidic acid binding 0.999999999966423 -3.35766284449078e-11 5 0 0 1680 17224 GO:0097100 supercoiled DNA binding 0.999999999966423 -3.35766284449078e-11 5 0 0 1680 17224 GO:0051434 BH3 domain binding 0.999999999966423 -3.35766284449078e-11 5 0 0 1680 17224 GO:0102953 hypoglycin A gamma-glutamyl transpeptidase activity 0.999999999966423 -3.35766284449078e-11 5 0 0 1680 17224 GO:0000829 inositol heptakisphosphate kinase activity 0.999999999966423 -3.35766284449078e-11 5 0 0 1680 17224 GO:0101020 estrogen 16-alpha-hydroxylase activity 0.999999999966423 -3.35766284449078e-11 5 0 0 1680 17224 GO:0001030 RNA polymerase III type 1 promoter DNA binding 0.999999999966423 -3.35766284449078e-11 5 0 0 1680 17224 GO:0004904 interferon receptor activity 0.999999999966423 -3.35766284449078e-11 5 0 0 1680 17224 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity 0.999999999966423 -3.35766284449078e-11 5 0 0 1680 17224 GO:0010385 double-stranded methylated DNA binding 0.999999999966423 -3.35766284449078e-11 5 0 0 1680 17224 GO:0005534 galactose binding 0.999999999966423 -3.35766284449078e-11 5 0 0 1680 17224 GO:0004668 protein-arginine deiminase activity 0.999999999966423 -3.35766284449078e-11 5 0 0 1680 17224 GO:0097371 MDM2/MDM4 family protein binding 0.999999999966423 -3.35766284449078e-11 5 0 0 1680 17224 GO:0004826 phenylalanine-tRNA ligase activity 0.999999999966423 -3.35766284449078e-11 5 0 0 1680 17224 GO:0004046 aminoacylase activity 0.999999999966423 -3.35766284449078e-11 5 0 0 1680 17224 GO:0004366 glycerol-3-phosphate O-acyltransferase activity 0.999999999966423 -3.35766284449078e-11 5 0 0 1680 17224 GO:0050833 pyruvate transmembrane transporter activity 0.999999999966423 -3.35766284449078e-11 5 0 0 1680 17224 GO:0043426 MRF binding 0.999999999966423 -3.35766284449078e-11 5 0 0 1680 17224 GO:0050129 N-formylglutamate deformylase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0008750 NAD(P)+ transhydrogenase (AB-specific) activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0015922 aspartate oxidase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0005368 taurine transmembrane transporter activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0102522 tRNA 4-demethylwyosine alpha-amino-alpha-carboxypropyltransferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0031812 P2Y1 nucleotide receptor binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0046539 histamine N-methyltransferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0017045 corticotropin-releasing hormone activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0004856 xylulokinase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0008419 RNA lariat debranching enzyme activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0035758 chemokine (C-C motif) ligand 21 binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0030380 interleukin-17E receptor binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0042610 CD8 receptor binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0061507 cyclic-GMP-AMP binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0042163 interleukin-12 beta subunit binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0043997 histone acetyltransferase activity (H4-K12 specific) 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0061812 cyclic ADP-ribose hydrolase 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:1905574 ganglioside GM2 binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0034038 deoxyhypusine synthase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0050897 cobalt ion binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0047613 aconitate decarboxylase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0047801 L-cysteine:2-oxoglutarate aminotransferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0017065 single-strand selective uracil DNA N-glycosylase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0008832 dGTPase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0071820 N-box binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0034602 oxoglutarate dehydrogenase (NAD+) activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0019118 phenanthrene-epoxide hydrolase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0008507 sodium:iodide symporter activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0000009 alpha-1,6-mannosyltransferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0072587 DNA topoisomerase (ATP-hydrolyzing) activator activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0072544 L-DOPA binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0008108 UDP-glucose:hexose-1-phosphate uridylyltransferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0010854 adenylate cyclase regulator activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0004051 arachidonate 5-lipoxygenase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0070611 histone methyltransferase activity (H3-R2 specific) 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0034459 ATP-dependent 3'-5' RNA helicase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0070736 protein-glycine ligase activity, initiating 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0003860 3-hydroxyisobutyryl-CoA hydrolase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0005142 interleukin-11 receptor binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0016794 diphosphoric monoester hydrolase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0016727 oxidoreductase activity, acting on CH or CH2 groups, oxygen as acceptor 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0097383 dIDP diphosphatase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0033787 cyanocobalamin reductase (cyanide-eliminating) activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0004102 choline O-acetyltransferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0070463 tubulin-dependent ATPase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0046523 S-methyl-5-thioribose-1-phosphate isomerase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0047621 acylpyruvate hydrolase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0047316 glutamine-phenylpyruvate transaminase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0103002 16-hydroxypalmitate dehydrogenase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0033781 cholesterol 24-hydroxylase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0008445 D-aspartate oxidase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0000016 lactase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0031729 CCR4 chemokine receptor binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0003830 beta-1,4-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0033229 cysteine transmembrane transporter activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0047402 protein-glucosylgalactosylhydroxylysine glucosidase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:1990595 mast cell secretagogue receptor activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0047962 glycine N-benzoyltransferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0061770 translation elongation factor binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0050353 trimethyllysine dioxygenase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0018114 threonine racemase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0004516 nicotinate phosphoribosyltransferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0050038 L-xylulose reductase (NADP+) activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:1904493 tetrahydrofolyl-poly(glutamate) polymer binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0004042 acetyl-CoA:L-glutamate N-acetyltransferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:1902118 calcidiol binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0106105 Ala-tRNA(Thr) hydrolase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0044610 FMN transmembrane transporter activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0097158 pre-mRNA intronic pyrimidine-rich binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0002059 thymine binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0031320 hexitol dehydrogenase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0033676 double-stranded DNA-dependent ATPase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0004310 farnesyl-diphosphate farnesyltransferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0044713 2-hydroxy-adenosine triphosphate pyrophosphatase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:1905172 RISC complex binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0008478 pyridoxal kinase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0036139 peptidyl-histidine dioxygenase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0061656 SUMO conjugating enzyme activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0098626 methylseleninic acid reductase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0030372 high molecular weight B cell growth factor receptor binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0032574 5'-3' RNA helicase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0004573 mannosyl-oligosaccharide glucosidase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0019135 deoxyhypusine monooxygenase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0036332 placental growth factor-activated receptor activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0052858 peptidyl-lysine acetyltransferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0004778 succinyl-CoA hydrolase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0033814 propanoyl-CoA C-acyltransferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0004883 glucocorticoid receptor activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0004578 chitobiosyldiphosphodolichol beta-mannosyltransferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0061599 molybdopterin molybdotransferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0017096 acetylserotonin O-methyltransferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0001179 RNA polymerase I transcription factor binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0102009 proline dipeptidase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0008120 ceramide glucosyltransferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0030586 [methionine synthase] reductase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0019767 IgE receptor activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0004446 inositol-hexakisphosphate phosphatase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0008119 thiopurine S-methyltransferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0001034 RNA polymerase III transcription factor activity, sequence-specific DNA binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0070975 FHA domain binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0046715 active borate transmembrane transporter activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0098973 structural constituent of postsynaptic actin cytoskeleton 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0017174 glycine N-methyltransferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0050115 myosin-light-chain-phosphatase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:1990003 IDP phosphatase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0045130 keratan sulfotransferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0047220 galactosylxylosylprotein 3-beta-galactosyltransferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0050023 L-fuconate dehydratase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0008609 alkylglycerone-phosphate synthase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0038186 lithocholic acid receptor activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0031768 ghrelin receptor binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0032093 SAM domain binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0008456 alpha-N-acetylgalactosaminidase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0004138 deoxyguanosine kinase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0052885 all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0008465 glycerate dehydrogenase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0070818 protoporphyrinogen oxidase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0034649 histone demethylase activity (H3-monomethyl-K4 specific) 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0004730 pseudouridylate synthase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0036458 hepatocyte growth factor binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0004362 glutathione-disulfide reductase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0035715 chemokine (C-C motif) ligand 2 binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0004131 cytosine deaminase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0050528 acyloxyacyl hydrolase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0008523 sodium-dependent multivitamin transmembrane transporter activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0009007 site-specific DNA-methyltransferase (adenine-specific) activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0004344 glucose dehydrogenase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0070320 inward rectifier potassium channel inhibitor activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0017084 delta1-pyrroline-5-carboxylate synthetase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0036455 iron-sulfur transferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0042292 URM1 activating enzyme activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0052918 dol-P-Man:Man(8)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0008386 cholesterol monooxygenase (side-chain-cleaving) activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0001791 IgM binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0032029 myosin tail binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0017098 sulfonylurea receptor binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0004381 fucosylgalactoside 3-alpha-galactosyltransferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0031716 calcitonin receptor binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0031851 kappa-type opioid receptor binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0046812 host cell surface binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0035538 carbohydrate response element binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:1902379 chemoattractant activity involved in axon guidance 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0038121 C-C motif chemokine 21 receptor activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0016784 3-mercaptopyruvate sulfurtransferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0008785 alkyl hydroperoxide reductase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0004978 corticotropin receptor activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0016034 maleylacetoacetate isomerase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0047186 N-acetylneuraminate 7-O(or 9-O)-acetyltransferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0004921 interleukin-11 receptor activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0008425 2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0004790 thioether S-methyltransferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0035410 dihydrotestosterone 17-beta-dehydrogenase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0052692 raffinose alpha-galactosidase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0004855 xanthine oxidase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:1905575 ganglioside GM3 binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0052821 DNA-7-methyladenine glycosylase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0052894 norspermine:oxygen oxidoreductase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0070774 phytoceramidase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0004080 biotin-[propionyl-CoA-carboxylase (ATP-hydrolyzing)] ligase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:1902388 ceramide 1-phosphate transporter activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0010855 adenylate cyclase inhibitor activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0033681 ATP-dependent 3'-5' DNA/RNA helicase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0070042 rRNA (uridine-N3-)-methyltransferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0008725 DNA-3-methyladenine glycosylase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0019807 aspartoacylase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0001760 aminocarboxymuconate-semialdehyde decarboxylase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0044714 2-hydroxy-(deoxy)adenosine-triphosphate pyrophosphatase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0008955 peptidoglycan glycosyltransferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0070612 histone methyltransferase activity (H2A-R3 specific) 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:1990738 pseudouridine 5'-phosphatase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0070733 protein adenylyltransferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0097382 deoxynucleoside-diphosphatase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0004397 histidine ammonia-lyase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0072586 DNA topoisomerase (ATP-hydrolyzing) regulator activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0047341 fucose-1-phosphate guanylyltransferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0005260 intracellularly ATP-gated chloride channel activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0047315 kynurenine-glyoxylate transaminase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0033858 N-acetylgalactosamine kinase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0005367 myo-inositol:sodium symporter activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0004306 ethanolamine-phosphate cytidylyltransferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0036468 L-dopa decarboxylase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0003905 alkylbase DNA N-glycosylase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0047273 galactosylgalactosylglucosylceramide beta-D-acetylgalactosaminyltransferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0140065 peptide butyryltransferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0031858 pituitary adenylate cyclase-activating polypeptide receptor binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0000831 inositol hexakisphosphate 6-kinase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0044603 protein adenylylhydrolase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0032500 muramyl dipeptide binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:1903924 estradiol binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0103067 4alpha-carboxy-5alpha-cholesta-8-en-3beta-ol:NAD(P)+ 3-dehydrogenase (decarboxylating) activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0008709 cholate 7-alpha-dehydrogenase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0070287 ferritin receptor activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0004810 tRNA adenylyltransferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0031715 C5L2 anaphylatoxin chemotactic receptor binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0019119 phenanthrene-9,10-epoxide hydrolase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0042164 interleukin-12 alpha subunit binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0042324 hypocretin receptor binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0015369 calcium:proton antiporter activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0031861 prolactin-releasing peptide receptor binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0098625 methylselenol reductase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0017005 3'-tyrosyl-DNA phosphodiesterase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0016847 1-aminocyclopropane-1-carboxylate synthase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0030629 U6 snRNA 3'-end binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0120092 crotonyl-CoA hydratase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0004838 L-tyrosine:2-oxoglutarate aminotransferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0050785 advanced glycation end-product receptor activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0010309 acireductone dioxygenase [iron(II)-requiring] activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0035757 chemokine (C-C motif) ligand 19 binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0004513 neolactotetraosylceramide alpha-2,3-sialyltransferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0004014 adenosylmethionine decarboxylase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0031883 taste receptor binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0034590 L-hydroxyproline transmembrane transporter activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0033882 choloyl-CoA hydrolase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0030108 HLA-A specific activating MHC class I receptor activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0004043 L-aminoadipate-semialdehyde dehydrogenase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:1902098 calcitriol binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0001856 complement component C5a binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0102076 beta,beta-carotene-9',10'-cleaving oxygenase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0051724 NAD transmembrane transporter activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0004824 lysine-tRNA ligase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0004164 diphthine synthase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0015191 L-methionine transmembrane transporter activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0050354 triokinase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0008518 folate:anion antiporter activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0000224 peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0004632 phosphopantothenate--cysteine ligase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0047856 dihydrocoumarin hydrolase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0047293 4-hydroxybenzoate nonaprenyltransferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0031707 endothelin A receptor binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0086082 cell adhesive protein binding involved in AV node cell-bundle of His cell communication 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0003692 left-handed Z-DNA binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0102483 scopolin beta-glucosidase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0008444 CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0003944 N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0046577 long-chain-alcohol oxidase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0018478 malonate-semialdehyde dehydrogenase (acetylating) activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0031370 eukaryotic initiation factor 4G binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0004078 biotin-[methylcrotonoyl-CoA-carboxylase] ligase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0038106 choriogonadotropin hormone binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0080132 fatty acid alpha-hydroxylase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0004349 glutamate 5-kinase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0008457 beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0016992 lipoate synthase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0050152 omega-amidase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0070678 preprotein binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0003919 FMN adenylyltransferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0050201 fucokinase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0004610 phosphoacetylglucosamine mutase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0004777 succinate-semialdehyde dehydrogenase (NAD+) activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0005395 eye pigment precursor transporter activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0004361 glutaryl-CoA dehydrogenase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0016213 linoleoyl-CoA desaturase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0035716 chemokine (C-C motif) ligand 12 binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0086038 calcium:sodium antiporter activity involved in regulation of cardiac muscle cell membrane potential 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0097162 MADS box domain binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0019772 low-affinity IgG receptor activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0004098 cerebroside-sulfatase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0032397 activating MHC class I receptor activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0102704 GDP-Man:Man2GlcNAc2-PP-dolichol alpha-1,6-mannosyltransferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0061598 molybdopterin adenylyltransferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0036403 arachidonate 8(S)-lipoxygenase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0102339 3-oxo-arachidoyl-CoA reductase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0004655 porphobilinogen synthase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0008397 sterol 12-alpha-hydroxylase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0003874 6-pyruvoyltetrahydropterin synthase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0033919 glucan 1,3-alpha-glucosidase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0050333 thiamin-triphosphatase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0031870 thromboxane A2 receptor binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0008761 UDP-N-acetylglucosamine 2-epimerase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0004561 alpha-N-acetylglucosaminidase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0030523 dihydrolipoamide S-acyltransferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0016414 O-octanoyltransferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0002058 uracil binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0005464 UDP-xylose transmembrane transporter activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0072518 Rho-dependent protein serine/threonine kinase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0046316 gluconokinase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0102167 [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine O-N-acetyl-alpha-D-glucosaminase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0008829 dCTP deaminase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0036317 tyrosyl-RNA phosphodiesterase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0030171 voltage-gated proton channel activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0004334 fumarylacetoacetase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0051786 all-trans-retinol 13,14-reductase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0008488 gamma-glutamyl carboxylase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:1990889 H4K20me3 modified histone binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0008843 endochitinase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0019779 Atg8 activating enzyme activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0019187 beta-1,4-mannosyltransferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0098619 selenocysteine-tRNA ligase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0097260 eoxin A4 synthase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0033778 7alpha-hydroxycholest-4-en-3-one 12alpha-hydroxylase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0004795 threonine synthase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0050346 trans-L-3-hydroxyproline dehydratase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0052929 ATP:3'-cytidine-cytidine-tRNA adenylyltransferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0035478 chylomicron binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0047545 2-hydroxyglutarate dehydrogenase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0046996 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, with NAD(P)H as one donor, and the other dehydrogenated 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0016730 oxidoreductase activity, acting on iron-sulfur proteins as donors 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0004760 serine-pyruvate transaminase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0001962 alpha-1,3-galactosyltransferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:1990829 C-rich single-stranded DNA binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0070976 TIR domain binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0047734 CDP-glycerol diphosphatase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0042586 peptide deformylase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0030977 taurine binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0019964 interferon-gamma binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0031151 histone methyltransferase activity (H3-K79 specific) 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0070694 deoxyribonucleoside 5'-monophosphate N-glycosidase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:1905577 ganglioside GP1c binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0052895 N1-acetylspermine:oxygen oxidoreductase (N1-acetylspermidine-forming) activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0052822 DNA-3-methylguanine glycosylase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0086090 voltage-gated potassium channel activity involved in SA node cell action potential repolarization 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0047166 1-alkenylglycerophosphoethanolamine O-acyltransferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0015343 siderophore transmembrane transporter activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0015117 thiosulfate transmembrane transporter activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0071164 RNA trimethylguanosine synthase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0015495 gamma-aminobutyric acid:proton symporter activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0030351 inositol-1,3,4,5,6-pentakisphosphate 3-phosphatase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0019811 cocaine binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0008905 mannose-phosphate guanylyltransferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0015361 low-affinity sodium:dicarboxylate symporter activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0008424 glycoprotein 6-alpha-L-fucosyltransferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0047988 hydroxyacid-oxoacid transhydrogenase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0070773 protein-N-terminal glutamine amidohydrolase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0036440 citrate synthase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0061898 all-trans retinoic acid 3,4-desaturase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0005147 oncostatin-M receptor binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0038117 C-C motif chemokine 19 receptor activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0004083 bisphosphoglycerate 2-phosphatase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0008437 thyrotropin-releasing hormone activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0047127 thiomorpholine-carboxylate dehydrogenase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0003934 GTP cyclohydrolase I activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0061920 protein propionyltransferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0030616 transforming growth factor beta receptor, common-partner cytoplasmic mediator activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0008521 acetyl-CoA transmembrane transporter activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0047225 acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0004479 methionyl-tRNA formyltransferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0033925 mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0050080 malonyl-CoA decarboxylase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0047326 inositol tetrakisphosphate 5-kinase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0047714 galactolipase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0004092 carnitine O-acetyltransferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0010856 adenylate cyclase activator activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0043843 ADP-specific glucokinase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0047290 (alpha-N-acetylneuraminyl-2,3-beta-galactosyl-1,3)-N-acetyl-galactosaminide 6-alpha-sialyltransferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0009020 tRNA (guanosine-2'-O-)-methyltransferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0050113 inositol oxygenase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0015660 formate efflux transmembrane transporter activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0052904 N1-acetylspermidine:oxygen oxidoreductase (3-acetamidopropanal-forming) activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0033682 ATP-dependent 5'-3' DNA/RNA helicase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:1904399 heparan sulfate binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0047012 sterol-4-alpha-carboxylate 3-dehydrogenase (decarboxylating) activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0004408 holocytochrome-c synthase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0050462 N-acetylneuraminate synthase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0001792 polymeric immunoglobulin receptor activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0005090 Sar guanyl-nucleotide exchange factor activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0086079 gap junction channel activity involved in Purkinje myocyte-ventricular cardiac muscle cell electrical coupling 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0008127 quercetin 2,3-dioxygenase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0035472 choriogonadotropin hormone receptor activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0046570 methylthioribulose 1-phosphate dehydratase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0015086 cadmium ion transmembrane transporter activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0004607 phosphatidylcholine-sterol O-acyltransferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0102752 1,4-alpha-glucan branching enzyme activity (using a glucosylated glycogenin as primer for glycogen synthesis) 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0019780 FAT10 activating enzyme activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0004398 histidine decarboxylase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0032556 pyrimidine deoxyribonucleotide binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0004423 iduronate-2-sulfatase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0004773 steryl-sulfatase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0018733 3,4-dihydrocoumarin hydrolase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0016149 translation release factor activity, codon specific 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0086039 calcium-transporting ATPase activity involved in regulation of cardiac muscle cell membrane potential 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0004108 citrate (Si)-synthase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0015136 sialic acid transmembrane transporter activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:1901641 ITP binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0001567 cholesterol 25-hydroxylase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0036219 GTP diphosphatase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0001596 angiotensin type I receptor activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0016517 interleukin-12 receptor activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0043423 3-phosphoinositide-dependent protein kinase binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0042012 interleukin-16 receptor activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:1990175 EH domain binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0032841 calcitonin binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0034246 mitochondrial sequence-specific DNA binding transcription factor activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0034722 gamma-glutamyl-peptidase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0004633 phosphopantothenoylcysteine decarboxylase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0140064 peptide crotonyltransferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0052926 dol-P-Man:Man(6)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:1990136 linoleate 9S-lipoxygenase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0015633 zinc-transporting ATPase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0043795 glyceraldehyde oxidoreductase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0030792 methylarsonite methyltransferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0042131 thiamine phosphate phosphatase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0031718 type 1 cannabinoid receptor binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0050121 N-acylglucosamine 2-epimerase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0015499 formate transmembrane transporter activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0015019 heparan-alpha-glucosaminide N-acetyltransferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0046623 sphingolipid-translocating ATPase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0036478 L-dopa decarboxylase activator activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0004744 retinal isomerase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0042937 tripeptide transmembrane transporter activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:1990439 MAP kinase serine/threonine phosphatase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0004751 ribose-5-phosphate isomerase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0015190 L-leucine transmembrane transporter activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0030379 neurotensin receptor activity, non-G-protein coupled 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0060175 brain-derived neurotrophic factor-activated receptor activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0051723 protein methylesterase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0005140 interleukin-9 receptor binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0008387 steroid 7-alpha-hydroxylase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0004511 tyrosine 3-monooxygenase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0018455 alcohol dehydrogenase [NAD(P)+] activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0016277 [myelin basic protein]-arginine N-methyltransferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0015126 canalicular bile acid transmembrane transporter activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0052830 inositol-1,3,4,6-tetrakisphosphate 6-phosphatase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0047305 (R)-3-amino-2-methylpropionate-pyruvate transaminase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0090624 endoribonuclease activity, cleaving miRNA-paired mRNA 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0004736 pyruvate carboxylase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0043849 Ras palmitoyltransferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0008891 glycolate oxidase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0008254 3'-nucleotidase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0061501 cyclic-GMP-AMP synthase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0017082 mineralocorticoid receptor activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0008963 phospho-N-acetylmuramoyl-pentapeptide-transferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0033204 ribonuclease P RNA binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0050277 sedoheptulokinase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0051267 CP2 mannose-ethanolamine phosphotransferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0016920 pyroglutamyl-peptidase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0008783 agmatinase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0047837 D-xylose 1-dehydrogenase (NADP+) activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0018549 methanethiol oxidase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0004149 dihydrolipoyllysine-residue succinyltransferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0003983 UTP:glucose-1-phosphate uridylyltransferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0033749 histone demethylase activity (H4-R3 specific) 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0003922 GMP synthase (glutamine-hydrolyzing) activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0003882 CDP-diacylglycerol-serine O-phosphatidyltransferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0061899 11-cis-retinal 3,4-desaturase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0016751 S-succinyltransferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0000994 RNA polymerase III core binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0002113 interleukin-33 binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0003991 acetylglutamate kinase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0031739 cholecystokinin receptor binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0005129 granulocyte macrophage colony-stimulating factor receptor binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0005009 insulin-activated receptor activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0015420 cobalamin-transporting ATPase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0004900 erythropoietin receptor activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0003947 (N-acetylneuraminyl)-galactosylglucosylceramide N-acetylgalactosaminyltransferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0003933 GTP cyclohydrolase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0017188 aspartate N-acetyltransferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0030760 pyridine N-methyltransferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0022894 Intermediate conductance calcium-activated potassium channel activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0046817 chemokine receptor antagonist activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0043754 dihydrolipoyllysine-residue (2-methylpropanoyl)transferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0004018 N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0016844 strictosidine synthase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0050646 5-oxo-6E,8Z,11Z,14Z-icosatetraenoic acid binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0015317 phosphate:proton symporter activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:1990955 G-rich single-stranded DNA binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0004654 polyribonucleotide nucleotidyltransferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0031724 CXCR5 chemokine receptor binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0004671 protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0034545 fumarylpyruvate hydrolase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0033878 hormone-sensitive lipase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0071713 para-aminobenzoyl-glutamate hydrolase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0008126 acetylesterase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0050355 triphosphatase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0099186 structural constituent of postsynapse 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0017020 myosin phosphatase regulator activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0045153 electron transporter, transferring electrons within CoQH2-cytochrome c reductase complex activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0031626 beta-endorphin binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0008458 carnitine O-octanoyltransferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0003921 GMP synthase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0004490 methylglutaconyl-CoA hydratase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0050146 nucleoside phosphotransferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0030697 S-adenosylmethionine-dependent tRNA (m5U54) methyltransferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0015112 nitrate transmembrane transporter activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0004333 fumarate hydratase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0008403 25-hydroxycholecalciferol-24-hydroxylase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0004564 beta-fructofuranosidase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0051732 polyribonucleotide kinase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0004168 dolichol kinase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0051424 corticotropin-releasing hormone binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0061697 protein-glutaryllysine deglutarylase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0015105 arsenite transmembrane transporter activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0031766 type 3 galanin receptor binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0038047 morphine receptor activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0036393 thiocyanate peroxidase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0004648 O-phospho-L-serine:2-oxoglutarate aminotransferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0070009 serine-type aminopeptidase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0047016 cholest-5-ene-3-beta,7-alpha-diol 3-beta-dehydrogenase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0036470 tyrosine 3-monooxygenase activator activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0102758 very-long-chain enoyl-CoA reductase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0031877 somatostatin receptor binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0061811 ADP-ribosyl cyclase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0061768 magnesium:sodium antiporter activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0033679 3'-5' DNA/RNA helicase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0045517 interleukin-20 receptor binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0097682 intracellular phosphatidylinositol-3,5-bisphosphate-sensitive cation channel activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0033867 Fas-activated serine/threonine kinase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0008442 3-hydroxyisobutyrate dehydrogenase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0047224 acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0004371 glycerone kinase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0031703 type 2 angiotensin receptor binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0052798 beta-galactoside alpha-2,3-sialyltransferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0031741 type B gastrin/cholecystokinin receptor binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0004324 ferredoxin-NADP+ reductase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0033885 10-hydroxy-9-(phosphonooxy)octadecanoate phosphatase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0004877 complement component C3b receptor activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0047256 lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0047726 iron-cytochrome-c reductase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0047291 lactosylceramide alpha-2,3-sialyltransferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0004733 pyridoxamine-phosphate oxidase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0000257 nitrilase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0032567 dGTP binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0038182 G-protein coupled bile acid receptor activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0031717 cannabinoid receptor binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0106078 histone succinyltransferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0009384 N-acylmannosamine kinase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0004742 dihydrolipoyllysine-residue acetyltransferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0001716 L-amino-acid oxidase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0001861 complement component C4b receptor activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0120108 DNA-3'-diphospho-5'-guanosine diphosphatase 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0032428 beta-N-acetylgalactosaminidase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0008480 sarcosine dehydrogenase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0061981 3-hydroxykynureninase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0102166 [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-threonine O-N-acetyl-alpha-D-glucosaminase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0047918 GDP-mannose 3,5-epimerase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0005053 peroxisome matrix targeting signal-2 binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0102797 geranial:oxygen oxidoreductase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0042011 interleukin-16 binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0102773 dihydroceramide kinase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0005141 interleukin-10 receptor binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0051264 mono-olein transacylation activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0034353 RNA pyrophosphohydrolase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0097573 glutathione oxidoreductase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0043998 H2A histone acetyltransferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0016153 urocanate hydratase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0008747 N-acetylneuraminate lyase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0070283 radical SAM enzyme activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0031805 type 8 metabotropic glutamate receptor binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0055103 ligase regulator activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0004034 aldose 1-epimerase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0030387 fructosamine-3-kinase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0008811 chloramphenicol O-acetyltransferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0009673 low-affinity phosphate transmembrane transporter activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0032560 guanyl deoxyribonucleotide binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0008775 acetate CoA-transferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0008973 phosphopentomutase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0030791 arsenite methyltransferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0017113 dihydropyrimidine dehydrogenase (NADP+) activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0070539 linoleic acid binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0004728 signal transducer, downstream of receptor, with protein tyrosine phosphatase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0061685 diphthine methylesterase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0035643 L-DOPA receptor activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0004595 pantetheine-phosphate adenylyltransferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0102116 laurate hydroxylase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0046970 NAD-dependent histone deacetylase activity (H4-K16 specific) 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0008336 gamma-butyrobetaine dioxygenase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0050560 aspartate-tRNA(Asn) ligase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0009400 signal transducer, downstream of receptor, with serine/threonine phosphatase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0032216 glucosaminyl-phosphotidylinositol O-acyltransferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0033989 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0008111 alpha-methylacyl-CoA racemase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0016250 N-sulfoglucosamine sulfohydrolase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0004336 galactosylceramidase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0003881 CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0000496 base pairing 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0047442 17-alpha-hydroxyprogesterone aldolase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0019970 interleukin-11 binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0050221 prostaglandin-E2 9-reductase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0004343 glucosamine 6-phosphate N-acetyltransferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0043544 lipoamide binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0035375 zymogen binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0008554 sodium-exporting ATPase activity, phosphorylative mechanism 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0010428 methyl-CpNpG binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0047704 bile-salt sulfotransferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0004503 monophenol monooxygenase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0004584 dolichyl-phosphate-mannose-glycolipid alpha-mannosyltransferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0070335 aspartate binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0039552 RIG-I binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0008112 nicotinamide N-methyltransferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0005316 high-affinity inorganic phosphate:sodium symporter activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0051748 UTP-monosaccharide-1-phosphate uridylyltransferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:1990272 anti-Mullerian hormone receptor activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0004997 thyrotropin-releasing hormone receptor activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0042356 GDP-4-dehydro-D-rhamnose reductase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0019153 protein-disulfide reductase (glutathione) activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0051916 granulocyte colony-stimulating factor binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0004148 dihydrolipoyl dehydrogenase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0061730 C-rich strand telomeric DNA binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:1902121 lithocholic acid binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0050512 lactosylceramide 4-alpha-galactosyltransferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0060422 peptidyl-dipeptidase inhibitor activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0035851 Krueppel-associated box domain binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0051903 S-(hydroxymethyl)glutathione dehydrogenase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0004498 calcidiol 1-monooxygenase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0004567 beta-mannosidase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0004491 methylmalonate-semialdehyde dehydrogenase (acylating) activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0004132 dCMP deaminase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0001128 RNA polymerase II transcription coactivator activity involved in preinitiation complex assembly 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0004454 ketohexokinase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0045030 UTP-activated nucleotide receptor activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0031765 type 2 galanin receptor binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0043739 G/U mismatch-specific uracil-DNA glycosylase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0019782 ISG15 activating enzyme activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0001681 sialate O-acetylesterase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0004339 glucan 1,4-alpha-glucosidase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0015421 oligopeptide-transporting ATPase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0001626 nociceptin receptor activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0015367 oxoglutarate:malate antiporter activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0015552 propionate transmembrane transporter activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0043890 N-acetylgalactosamine-6-sulfatase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0052917 dol-P-Man:Man(7)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0072555 17-beta-ketosteroid reductase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0052731 phosphocholine phosphatase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0035248 alpha-1,4-N-acetylgalactosaminyltransferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0052902 spermidine:oxygen oxidoreductase (3-aminopropanal-forming) activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0086078 gap junction channel activity involved in bundle of His cell-Purkinje myocyte electrical coupling 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0052831 inositol-1,3,4,6-tetrakisphosphate 1-phosphatase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0004964 luteinizing hormone receptor activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0010348 lithium:proton antiporter activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0035597 N6-isopentenyladenosine methylthiotransferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0052884 all-trans-retinyl-palmitate hydrolase, 11-cis retinol forming activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0120017 intermembrane ceramide transfer activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0030233 deoxynucleotide transmembrane transporter activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0061605 molybdopterin-synthase adenylyltransferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0071714 icosanoid transmembrane transporter activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0003978 UDP-glucose 4-epimerase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0005477 pyruvate secondary active transmembrane transporter activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0004001 adenosine kinase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0033142 progesterone receptor binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0004077 biotin-[acetyl-CoA-carboxylase] ligase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0035598 N6-threonylcarbomyladenosine methylthiotransferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0036130 prostaglandin H2 endoperoxidase reductase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0001621 ADP receptor activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0030273 melanin-concentrating hormone receptor activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0106075 peptide N-succinyltransferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0030735 carnosine N-methyltransferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0004631 phosphomevalonate kinase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0004492 methylmalonyl-CoA decarboxylase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0103066 4alpha-carboxy-4beta-methyl-5alpha-cholesta-8-en-3beta-ol:NAD(P)+ 3-oxidoreductase (decarboxylating) activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0050031 L-pipecolate oxidase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0071890 bicarbonate binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0030748 amine N-methyltransferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0003939 L-iditol 2-dehydrogenase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0005334 norepinephrine:sodium symporter activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0030984 kininogen binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0031895 V1B vasopressin receptor binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0008116 prostaglandin-I synthase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0008887 glycerate kinase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0008115 sarcosine oxidase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0031764 type 1 galanin receptor binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0003952 NAD+ synthase (glutamine-hydrolyzing) activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0052732 phosphoethanolamine phosphatase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0043916 DNA-7-methylguanine glycosylase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0045340 mercury ion binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0042658 MHC class II protein binding, via antigen binding groove 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0098782 mechanosensitived potassium channel activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0008893 guanosine-3',5'-bis(diphosphate) 3'-diphosphatase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0015195 L-threonine transmembrane transporter activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0004476 mannose-6-phosphate isomerase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0002135 CTP binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0031835 substance P receptor binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0016519 gastric inhibitory peptide receptor activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0050561 glutamate-tRNA(Gln) ligase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0003842 1-pyrroline-5-carboxylate dehydrogenase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0052890 oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0061896 all-trans retinol 3,4-desaturase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0140069 histone butyryltransferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0016843 amine-lyase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0001226 RNA polymerase II transcription corepressor binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0047874 dolichyldiphosphatase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0005353 fructose transmembrane transporter activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0043221 SMC family protein binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0004462 lactoylglutathione lyase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0047685 amine sulfotransferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0004378 GDP-Man:Man1GlcNAc2-PP-Dol alpha-1,3-mannosyltransferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0008689 3-demethylubiquinone-9 3-O-methyltransferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0047276 N-acetyllactosaminide 3-alpha-galactosyltransferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0005309 creatine:sodium symporter activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:1990833 clathrin-uncoating ATPase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0086076 gap junction channel activity involved in atrial cardiac muscle cell-AV node cell electrical coupling 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0052906 tRNA (guanine(37)-N(1))-methyltransferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0016496 substance P receptor activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:1990930 RNA N1-methyladenosine dioxygenase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:1990407 calcitonin gene-related peptide binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0043337 CDP-diacylglycerol-phosphatidylglycerol phosphatidyltransferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0070547 L-tyrosine aminotransferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0004835 tubulin-tyrosine ligase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0047939 L-glucuronate reductase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0032575 ATP-dependent 5'-3' RNA helicase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0004418 hydroxymethylbilane synthase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0036327 VEGF-B-activated receptor activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0035400 histone tyrosine kinase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0072582 17-beta-hydroxysteroid dehydrogenase (NADP+) activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0047865 dimethylglycine dehydrogenase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0016768 spermine synthase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0052835 inositol-3,4,6-trisphosphate 1-kinase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0010844 recombination hotspot binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0030412 formimidoyltetrahydrofolate cyclodeaminase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0004979 beta-endorphin receptor activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0004152 dihydroorotate dehydrogenase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0015658 branched-chain amino acid transmembrane transporter activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0033678 5'-3' DNA/RNA helicase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0052817 very long chain acyl-CoA hydrolase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0036055 protein-succinyllysine desuccinylase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0004044 amidophosphoribosyltransferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0070551 endoribonuclease activity, cleaving siRNA-paired mRNA 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0033699 DNA 5'-adenosine monophosphate hydrolase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0009000 selenocysteine lyase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0043865 methionine transmembrane transporter activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0005252 open rectifier potassium channel activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0019150 D-ribulokinase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0004037 allantoicase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0030611 arsenate reductase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0008817 cob(I)yrinic acid a,c-diamide adenosyltransferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0051747 cytosine C-5 DNA demethylase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0031249 denatured protein binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0015211 purine nucleoside transmembrane transporter activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0033981 D-dopachrome decarboxylase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0042018 interleukin-22 receptor activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:1990165 single-strand break-containing DNA binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0008482 sulfite oxidase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0042931 enterobactin transmembrane transporter activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0047730 carnosine synthase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0052598 histamine oxidase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0034417 bisphosphoglycerate 3-phosphatase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0004411 homogentisate 1,2-dioxygenase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0046921 alpha-(1->6)-fucosyltransferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0050571 1,5-anhydro-D-fructose reductase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0070119 ciliary neurotrophic factor binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0050313 sulfur dioxygenase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0005034 osmosensor activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0036524 protein deglycase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0044594 17-beta-hydroxysteroid dehydrogenase (NAD+) activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0008995 ribonuclease E activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0000497 base pairing with DNA 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0052600 propane-1,3-diamine oxidase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0042624 ATPase activity, uncoupled 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0051265 diolein transacylation activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0102555 octanoyl transferase activity (acting on glycine-cleavage complex H protein) 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:1990244 histone kinase activity (H2A-T120 specific) 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0061542 3-demethylubiquinone-n 3-O-methyltransferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0102005 2-octaprenyl-6-methoxy-1,4-benzoquinone methylase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0150025 oxidised low-density lipoprotein particle receptor activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0032003 interleukin-28 receptor binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0005175 CD27 receptor binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0031840 type 2 neuromedin U receptor binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0106050 tRNA 2'-O-methyltransferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0005199 structural constituent of cell wall 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0031763 galanin receptor binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0001616 growth hormone secretagogue receptor activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0030580 quinone cofactor methyltransferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0047015 3-hydroxy-2-methylbutyryl-CoA dehydrogenase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0032448 DNA hairpin binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0047280 nicotinamide phosphoribosyltransferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0018773 acetylpyruvate hydrolase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0044717 8-hydroxy-dADP phosphatase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0018112 proline racemase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0032440 2-alkenal reductase [NAD(P)] activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0008892 guanine deaminase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0097372 NAD-dependent histone deacetylase activity (H3-K18 specific) 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0103046 alanylglutamate dipeptidase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0031834 neurokinin receptor binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0003940 L-iduronidase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:1990450 linear polyubiquitin binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0004642 phosphoribosylformylglycinamidine synthase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0008705 methionine synthase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:1902122 chenodeoxycholic acid binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:1904599 advanced glycation end-product binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0031770 growth hormone-releasing hormone receptor binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0008768 UDP-sugar diphosphatase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0090409 malonyl-CoA synthetase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0031855 oxytocin receptor binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0090560 2-(3-amino-3-carboxypropyl)histidine synthase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0004058 aromatic-L-amino-acid decarboxylase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0031771 type 1 hypocretin receptor binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0004113 2',3'-cyclic-nucleotide 3'-phosphodiesterase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0052725 inositol-1,3,4-trisphosphate 6-kinase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0072572 poly-ADP-D-ribose binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0047325 inositol tetrakisphosphate 1-kinase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0031811 G-protein coupled nucleotide receptor binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0033735 aspartate dehydrogenase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0035516 oxidative DNA demethylase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0004326 tetrahydrofolylpolyglutamate synthase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0036134 12-hydroxyheptadecatrienoic acid synthase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0015538 sialic acid:proton symporter activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0005302 L-tyrosine transmembrane transporter activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0004638 phosphoribosylaminoimidazole carboxylase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0097020 COPII adaptor activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0009013 succinate-semialdehyde dehydrogenase [NAD(P)+] activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0086087 voltage-gated potassium channel activity involved in bundle of His cell action potential repolarization 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0003834 beta-carotene 15,15'-monooxygenase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0052928 CTP:3'-cytidine-tRNA cytidylyltransferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0033819 lipoyl(octanoyl) transferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0046526 D-xylulose reductase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0015139 alpha-ketoglutarate transmembrane transporter activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0032406 MutLbeta complex binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0090416 nicotinate transmembrane transporter activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0048040 UDP-glucuronate decarboxylase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0120016 intermembrane sphingolipid transfer activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0071424 rRNA (cytosine-N4-)-methyltransferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0001512 dihydronicotinamide riboside quinone reductase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0017178 diphthine-ammonia ligase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0042083 5,10-methylenetetrahydrofolate-dependent methyltransferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0051908 double-stranded DNA 5'-3' exodeoxyribonuclease activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0001872 (1->3)-beta-D-glucan binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0016826 hydrolase activity, acting on acid sulfur-nitrogen bonds 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0008531 riboflavin kinase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0033560 folate reductase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0002083 4-hydroxybenzoate decaprenyltransferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0047936 glucose 1-dehydrogenase [NAD(P)] activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0050337 thiosulfate-thiol sulfurtransferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0047105 4-trimethylammoniobutyraldehyde dehydrogenase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0102340 3-oxo-behenoyl-CoA reductase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0004463 leukotriene-A4 hydrolase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0031723 CXCR4 chemokine receptor binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0008894 guanosine-5'-triphosphate,3'-diphosphate diphosphatase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0004059 aralkylamine N-acetyltransferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0031772 type 2 hypocretin receptor binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0050124 N-acylneuraminate-9-phosphatase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0004801 sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0000121 glycerol-1-phosphatase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0017061 S-methyl-5-thioadenosine phosphorylase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0016979 lipoate-protein ligase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0031208 POZ domain binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0004585 ornithine carbamoyltransferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0052825 inositol-1,3,4,5,6-pentakisphosphate 1-phosphatase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0052903 N1-acetylspermine:oxygen oxidoreductase (3-acetamidopropanal-forming) activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0000824 inositol tetrakisphosphate 3-kinase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0044508 glucagon-like peptide 1 receptor activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0030504 inorganic diphosphate transmembrane transporter activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0070626 (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate AMP-lyase (fumarate-forming) activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0015130 mevalonate transmembrane transporter activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0030110 HLA-C specific inhibitory MHC class I receptor activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0070002 glutamic-type peptidase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0004799 thymidylate synthase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0000825 inositol tetrakisphosphate 6-kinase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0005144 interleukin-13 receptor binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0036326 VEGF-A-activated receptor activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0070224 sulfide:quinone oxidoreductase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0102390 mycophenolic acid acyl-glucuronide esterase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0030623 U5 snRNA binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0003878 ATP citrate synthase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0048270 methionine adenosyltransferase regulator activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0003972 RNA ligase (ATP) activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0001587 Gq/11-coupled serotonin receptor activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0001918 farnesylated protein binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0003975 UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:1990188 euchromatin binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0052925 dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0036054 protein-malonyllysine demalonylase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0046554 malate dehydrogenase (NADP+) activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0004941 beta2-adrenergic receptor activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0036105 peroxisome membrane class-1 targeting sequence binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0036131 prostaglandin D2 11-ketoreductase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0030184 nitric oxide transmembrane transporter activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0004155 6,7-dihydropteridine reductase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:1990275 preribosome binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0047312 L-phenylalanine:pyruvate aminotransferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0061712 tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-methylthiotransferase 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0050648 5(S)-hydroxyperoxy-6E,8Z,11Z,14Z-icosatetraenoic acid binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0061897 all-trans retinal 3,4-desaturase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0004569 glycoprotein endo-alpha-1,2-mannosidase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0031737 CX3C chemokine receptor binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0016731 oxidoreductase activity, acting on iron-sulfur proteins as donors, NAD or NADP as acceptor 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0002055 adenine binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0016495 C-X3-C chemokine receptor activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0004493 methylmalonyl-CoA epimerase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0035299 inositol pentakisphosphate 2-kinase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0008434 calcitriol receptor activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0000332 template for synthesis of G-rich strand of telomere DNA activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0036222 XTP diphosphatase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0004484 mRNA guanylyltransferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0047395 glycerophosphoinositol glycerophosphodiesterase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0052597 diamine oxidase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:1901640 XTP binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0047747 cholate-CoA ligase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0000250 lanosterol synthase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0045127 N-acetylglucosamine kinase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0016287 glycerone-phosphate O-acyltransferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0015094 lead ion transmembrane transporter activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0016711 flavonoid 3'-monooxygenase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0009917 sterol 5-alpha reductase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0015054 gastrin receptor activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0015039 NADPH-adrenodoxin reductase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:1990984 tRNA demethylase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0036143 kringle domain binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0004394 heparan sulfate 2-O-sulfotransferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0052657 guanine phosphoribosyltransferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0008493 tetracycline transmembrane transporter activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0052909 18S rRNA (adenine(1779)-N(6)/adenine(1780)-N(6))-dimethyltransferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0097655 serpin family protein binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0044595 decaprenyldihydroxybenzoate methyltransferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0033791 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoyl-CoA 24-hydroxylase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0019115 benzaldehyde dehydrogenase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0046403 polynucleotide 3'-phosphatase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0098621 phosphoseryl-selenocysteinyl-tRNA selenium transferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0008753 NADPH dehydrogenase (quinone) activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0043994 histone acetyltransferase activity (H3-K23 specific) 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:1990883 rRNA cytidine N-acetyltransferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0099077 histone-dependent DNA binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0035175 histone kinase activity (H3-S10 specific) 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0004641 phosphoribosylformylglycinamidine cyclo-ligase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0051392 tRNA N-acetyltransferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0015098 molybdate ion transmembrane transporter activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0031854 orexigenic neuropeptide QRFP receptor binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0047444 N-acylneuraminate-9-phosphate synthase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0045352 interleukin-1 Type I receptor antagonist activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0047820 D-glutamate cyclase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0052726 inositol-1,3,4-trisphosphate 5-kinase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0047578 4-hydroxyglutamate transaminase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0061799 cyclic pyranopterin monophosphate synthase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0004325 ferrochelatase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0047969 glyoxylate oxidase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0004639 phosphoribosylaminoimidazolesuccinocarboxamide synthase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0070615 nucleosome-dependent ATPase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0030407 formimidoyltransferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0051433 BH2 domain binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0043250 sodium-dependent organic anion transmembrane transporter activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0008448 N-acetylglucosamine-6-phosphate deacetylase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0038046 enkephalin receptor activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0008721 D-serine ammonia-lyase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0030696 tRNA (m5U54) methyltransferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0070037 rRNA (pseudouridine) methyltransferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0035730 S-nitrosoglutathione binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0047042 androsterone dehydrogenase (B-specific) activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0120053 ribitol beta-1,4-xylosyltransferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0005133 interferon-gamma receptor binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0043733 DNA-3-methylbase glycosylase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0102707 S-adenosyl-L-methionine:beta-alanine N-methyltransferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0103045 methione N-acyltransferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0102200 N-acetylphosphatidylethanolamine-hydrolysing phospholipas activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0050632 propionyl-CoA C2-trimethyltridecanoyltransferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0042017 interleukin-22 binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0033961 cis-stilbene-oxide hydrolase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0070984 SET domain binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0030342 1-alpha,25-dihydroxyvitamin D3 24-hydroxylase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0050429 calcium-dependent phospholipase C activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:1990081 trimethylamine receptor activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0098918 structural constituent of synapse 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0033871 [heparan sulfate]-glucosamine 3-sulfotransferase 2 activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0015131 oxaloacetate transmembrane transporter activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0047658 alpha-amino-acid esterase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0003844 1,4-alpha-glucan branching enzyme activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0005461 UDP-glucuronic acid transmembrane transporter activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0097726 LEM domain binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0033328 peroxisome membrane targeting sequence binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0052666 tRNA (cytosine-2'-O-)-methyltransferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0043210 alkanesulfonate binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0008841 dihydrofolate synthase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0008555 chloride-transporting ATPase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0033746 histone demethylase activity (H3-R2 specific) 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0050647 5-hydroxy-6E,8Z,11Z,14Z-icosatetraenoic acid binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0047743 chlordecone reductase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0019810 putrescine binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0050479 glyceryl-ether monooxygenase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:1990817 RNA adenylyltransferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:1990448 exon-exon junction complex binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0070553 nicotinic acid receptor activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0099130 estrogen binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0102769 dihydroceramide glucosyltransferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0004588 orotate phosphoribosyltransferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0019778 Atg12 activating enzyme activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0047888 fatty acid peroxidase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0000823 inositol-1,4,5-trisphosphate 6-kinase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0038164 thrombopoietin receptor activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0003999 adenine phosphoribosyltransferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0071997 glutathione S-conjugate-transporting ATPase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0042084 5-methyltetrahydrofolate-dependent methyltransferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0046980 tapasin binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0004590 orotidine-5'-phosphate decarboxylase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0043874 acireductone synthase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0042497 triacyl lipopeptide binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0047560 3-dehydrosphinganine reductase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0005018 platelet-derived growth factor alpha-receptor activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0016430 tRNA (adenine-N6-)-methyltransferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0004061 arylformamidase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0090600 alpha-1,3-glucosidase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0004363 glutathione synthase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0004676 3-phosphoinositide-dependent protein kinase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0102524 tRNAPhe (7-(3-amino-3-carboxypropyl)wyosine37-C2)-hydroxylase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0031867 EP4 subtype prostaglandin E2 receptor binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0071795 K11-linked polyubiquitin modification-dependent protein binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0008613 diuretic hormone activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0031682 G-protein gamma-subunit binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0102549 1-18:1-2-16:0-monogalactosyldiacylglycerol lipase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0102341 3-oxo-lignoceroyl-CoA reductase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0017172 cysteine dioxygenase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0016231 beta-N-acetylglucosaminidase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0004494 methylmalonyl-CoA mutase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0030338 CMP-N-acetylneuraminate monooxygenase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0047915 ganglioside galactosyltransferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0052591 sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0031769 glucagon receptor binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0004341 gluconolactonase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0031750 D3 dopamine receptor binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0031559 oxidosqualene cyclase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0047946 glutamine N-acyltransferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0051736 ATP-dependent polyribonucleotide 5'-hydroxyl-kinase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0004085 butyryl-CoA dehydrogenase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0008118 N-acetyllactosaminide alpha-2,3-sialyltransferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0047840 dCTP diphosphatase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0016990 arginine deiminase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0038051 glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0070260 5'-tyrosyl-DNA phosphodiesterase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0070337 3'-flap-structured DNA binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0030729 acetoacetate-CoA ligase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0034634 glutathione transmembrane transporter activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0016785 transferase activity, transferring selenium-containing groups 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0003974 UDP-N-acetylglucosamine 4-epimerase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0008792 arginine decarboxylase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0004960 thromboxane receptor activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0008452 RNA ligase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0043273 CTPase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0030377 urokinase plasminogen activator receptor activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0052590 sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0033897 ribonuclease T2 activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0099142 intracellularly ATP-gated ion channel activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0008897 holo-[acyl-carrier-protein] synthase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0008123 cholesterol 7-alpha-monooxygenase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:1904454 ubiquitin-specific protease activity involved in positive regulation of ERAD pathway 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0030429 kynureninase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0008495 protoheme IX farnesyltransferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0004056 argininosuccinate lyase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0001225 RNA polymerase II transcription coactivator binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0031857 type 1 parathyroid hormone receptor binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0002196 Ser-tRNA(Ala) hydrolase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0000225 N-acetylglucosaminylphosphatidylinositol deacetylase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0045027 DNA end binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0051722 protein C-terminal methylesterase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0071566 UFM1 activating enzyme activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0045353 interleukin-1 Type II receptor antagonist activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0016913 follicle-stimulating hormone activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0044105 L-xylulose reductase (NAD+) activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0102342 3-oxo-cerotoyl-CoA reductase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0052899 N(1),N(12)-diacetylspermine:oxygen oxidoreductase (3-acetamidopropanal-forming) activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0010420 polyprenyldihydroxybenzoate methyltransferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0034012 FAD-AMP lyase (cyclizing) activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0061750 acid sphingomyelin phosphodiesterase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0086040 sodium:proton antiporter activity involved in regulation of cardiac muscle cell membrane potential 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0047620 acylglycerol kinase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0016815 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in nitriles 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0045703 ketoreductase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0032358 oxidized pyrimidine DNA binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0008803 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0004603 phenylethanolamine N-methyltransferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0031714 C5a anaphylatoxin chemotactic receptor binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0031839 type 1 neuromedin U receptor binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0061798 GTP 3',8'-cyclase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:1904492 Ac-Asp-Glu binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0003957 NAD(P)+ transhydrogenase (B-specific) activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0018025 calmodulin-lysine N-methyltransferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0001850 complement component C3a binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0046911 metal chelating activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0004644 phosphoribosylglycinamide formyltransferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0097621 monoamine oxidase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0003912 DNA nucleotidylexotransferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0001010 transcription factor activity, sequence-specific DNA binding transcription factor recruiting 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0034899 trimethylamine monooxygenase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:1902444 riboflavin binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0061627 S-methylmethionine-homocysteine S-methyltransferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0015439 heme-transporting ATPase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0005335 serotonin:sodium symporter activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0016596 thienylcyclohexylpiperidine binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0004796 thromboxane-A synthase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0004380 glycoprotein-fucosylgalactoside alpha-N-acetylgalactosaminyltransferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0052855 ADP-dependent NAD(P)H-hydrate dehydratase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0035731 dinitrosyl-iron complex binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0004068 aspartate 1-decarboxylase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0018271 biotin-protein ligase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0047394 glycerophosphoinositol inositolphosphodiesterase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0035755 cardiolipin hydrolase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0046904 calcium oxalate binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:1905594 resveratrol binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0003877 ATP adenylyltransferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0036004 GAF domain binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0004581 dolichyl-phosphate beta-glucosyltransferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0019799 tubulin N-acetyltransferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0043783 oxidoreductase activity, oxidizing metal ions with flavin as acceptor 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0015055 secretin receptor activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0042922 neuromedin U receptor binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:1902387 ceramide 1-phosphate binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0102102 homocarnosine synthase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0042947 glucoside transmembrane transporter activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0047860 diiodophenylpyruvate reductase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0080048 GDP-D-glucose phosphorylase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0001074 transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding involved in preinitiation complex assembly 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0050011 itaconyl-CoA hydratase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0052826 inositol hexakisphosphate 2-phosphatase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0031695 alpha-2B adrenergic receptor binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0044596 3-demethylubiquinone-10 3-O-methyltransferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0098601 selenomethionine adenosyltransferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0102571 [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine/L-threonine O-N-acetyl-alpha-D-glucosaminase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0004079 biotin-[methylmalonyl-CoA-carboxytransferase] ligase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0140068 histone crotonyltransferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0047020 15-hydroxyprostaglandin-D dehydrogenase (NADP+) activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0097161 DH domain binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0045183 translation factor activity, non-nucleic acid binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0047159 1-alkenylglycerophosphocholine O-acyltransferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0008808 cardiolipin synthase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0050577 GDP-L-fucose synthase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0000252 C-3 sterol dehydrogenase (C-4 sterol decarboxylase) activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0004925 prolactin receptor activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0018467 formaldehyde dehydrogenase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0004509 steroid 21-monooxygenase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0061609 fructose-1-phosphate aldolase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0000170 sphingosine hydroxylase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:1904265 ubiquitin-specific protease activity involved in negative regulation of retrograde protein transport, ER to cytosol 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0052927 CTP:tRNA cytidylyltransferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0061604 molybdopterin-synthase sulfurtransferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:1904408 melatonin binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0004587 ornithine-oxo-acid transaminase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0052717 tRNA-specific adenosine-34 deaminase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0008852 exodeoxyribonuclease I activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:1990931 RNA N6-methyladenosine dioxygenase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0004961 thromboxane A2 receptor activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0015362 high-affinity sodium:dicarboxylate symporter activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0060703 deoxyribonuclease inhibitor activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0030624 U6atac snRNA binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0001532 interleukin-21 receptor activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0052872 tocotrienol omega-hydroxylase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0019145 aminobutyraldehyde dehydrogenase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0004347 glucose-6-phosphate isomerase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0017125 deoxycytidyl transferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0004729 oxygen-dependent protoporphyrinogen oxidase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0018585 fluorene oxygenase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0036220 ITP diphosphatase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0047198 cysteine-S-conjugate N-acetyltransferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0035642 histone methyltransferase activity (H3-R17 specific) 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0016521 pituitary adenylate cyclase activating polypeptide activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0003937 IMP cyclohydrolase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0004766 spermidine synthase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0016497 substance K receptor activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:1905030 voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0047191 1-alkylglycerophosphocholine O-acyltransferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0019969 interleukin-10 binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0005456 CMP-N-acetylneuraminate transmembrane transporter activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0043136 glycerol-3-phosphatase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0008903 hydroxypyruvate isomerase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0044549 GTP cyclohydrolase binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0070892 lipoteichoic acid receptor activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0035438 cyclic-di-GMP binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0036328 VEGF-C-activated receptor activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0015052 beta3-adrenergic receptor activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0047945 L-glutamine:pyruvate aminotransferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0086041 voltage-gated potassium channel activity involved in SA node cell action potential depolarization 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0047800 cysteamine dioxygenase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0061654 NEDD8 conjugating enzyme activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0008117 sphinganine-1-phosphate aldolase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0031788 motilin receptor binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0000095 S-adenosyl-L-methionine transmembrane transporter activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0030294 receptor signaling protein tyrosine kinase inhibitor activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0001096 TFIIF-class transcription factor binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0032408 MutSbeta complex binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0008068 extracellularly glutamate-gated chloride channel activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0008455 alpha-1,6-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0035485 adenine/guanine mispair binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0015152 glucose-6-phosphate transmembrane transporter activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0003837 beta-ureidopropionase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0004807 triose-phosphate isomerase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0044716 8-oxo-GDP phosphatase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0102798 heptaldehyde:oxygen oxidoreductase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0031700 adrenomedullin receptor binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0030251 guanylate cyclase inhibitor activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0030290 sphingolipid activator protein activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0047547 2-methylcitrate dehydratase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0031405 lipoic acid binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0048244 phytanoyl-CoA dioxygenase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0030731 guanidinoacetate N-methyltransferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0015390 purine-specific nucleoside:sodium symporter activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0031856 parathyroid hormone receptor binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0002153 steroid receptor RNA activator RNA binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0004575 sucrose alpha-glucosidase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0047693 ATP diphosphatase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0019962 type I interferon binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0070546 L-phenylalanine aminotransferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0019975 interleukin-17 binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0005170 neurotrophin TRKC receptor binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0008418 protein-N-terminal asparagine amidohydrolase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0010852 cyclase inhibitor activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0008700 4-hydroxy-2-oxoglutarate aldolase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0061690 lipoamidase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0002061 pyrimidine nucleobase binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0004686 elongation factor-2 kinase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0005130 granulocyte colony-stimulating factor receptor binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0030409 glutamate formimidoyltransferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0045131 pre-mRNA branch point binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0050046 lathosterol oxidase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0016964 alpha-2 macroglobulin receptor activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0035501 MH1 domain binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0005307 choline:sodium symporter activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0004475 mannose-1-phosphate guanylyltransferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0047021 15-hydroxyprostaglandin dehydrogenase (NADP+) activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0004637 phosphoribosylamine-glycine ligase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0047963 glycine N-choloyltransferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0036140 peptidyl-asparagine 3-dioxygenase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0008446 GDP-mannose 4,6-dehydratase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0008802 betaine-aldehyde dehydrogenase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0004643 phosphoribosylaminoimidazolecarboxamide formyltransferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0004350 glutamate-5-semialdehyde dehydrogenase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0033798 thyroxine 5-deiodinase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0045513 interleukin-27 binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0016793 triphosphoric monoester hydrolase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:1990518 single-stranded DNA-dependent ATP-dependent 3'-5' DNA helicase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0047323 [3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring)] kinase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0031841 neuropeptide Y receptor binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0004757 sepiapterin reductase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0004395 hexaprenyldihydroxybenzoate methyltransferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0120048 U6 snRNA (adenine-(43)-N(6))-methyltransferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0050444 aquacobalamin reductase (NADPH) activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0046789 host cell surface receptor binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0047066 phospholipid-hydroperoxide glutathione peroxidase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0015431 glutathione S-conjugate-exporting ATPase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0004057 arginyltransferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0004876 complement component C3a receptor activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:1990174 phosphodiesterase decapping endonuclease activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0043035 chromatin insulator sequence binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0070974 POU domain binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0017024 myosin I binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0035401 histone kinase activity (H3-Y41 specific) 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0030572 phosphatidyltransferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0061663 NEDD8 ligase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0097160 polychlorinated biphenyl binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0038048 dynorphin receptor activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0031896 V2 vasopressin receptor binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0004139 deoxyribose-phosphate aldolase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0004747 ribokinase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0050649 testosterone 6-beta-hydroxylase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0070524 11-beta-hydroxysteroid dehydrogenase (NADP+) activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0015578 mannose transmembrane transporter activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0030378 serine racemase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0000334 3-hydroxyanthranilate 3,4-dioxygenase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0052599 methylputrescine oxidase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0035226 glutamate-cysteine ligase catalytic subunit binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0033737 1-pyrroline dehydrogenase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0102113 hypoxia-inducible factor-asparagine oxygenase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0005115 receptor tyrosine kinase-like orphan receptor binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0005519 cytoskeletal regulatory protein binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0015132 prostaglandin transmembrane transporter activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0047453 ATP-dependent NAD(P)H-hydrate dehydratase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0008794 arsenate reductase (glutaredoxin) activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0004853 uroporphyrinogen decarboxylase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0008812 choline dehydrogenase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0047349 D-ribitol-5-phosphate cytidylyltransferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0052381 tRNA dimethylallyltransferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0016412 serine O-acyltransferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0005150 interleukin-1, Type I receptor binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0005020 stem cell factor receptor activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0004508 steroid 17-alpha-monooxygenase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0008470 isovaleryl-CoA dehydrogenase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0051996 squalene synthase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0042988 X11-like protein binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0052907 23S rRNA (adenine(1618)-N(6))-methyltransferase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0031071 cysteine desulfurase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0051750 delta3,5-delta2,4-dienoyl-CoA isomerase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0047676 arachidonate-CoA ligase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0005369 taurine:sodium symporter activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0102008 cytosolic dipeptidase activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0042007 interleukin-18 binding 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0004486 methylenetetrahydrofolate dehydrogenase [NAD(P)+] activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0050290 sphingomyelin phosphodiesterase D activity 0.999999999966984 -3.30158400618785e-11 1 0 0 1680 17224 GO:0004931 extracellularly ATP-gated cation channel activity 0.999999999967141 -3.28586388146187e-11 7 0 0 1680 17224 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity 0.999999999967141 -3.28586388146187e-11 7 0 0 1680 17224 GO:0016714 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen 0.999999999967141 -3.28586388146187e-11 7 0 0 1680 17224 GO:0042895 antibiotic transmembrane transporter activity 0.999999999967141 -3.28586388146187e-11 7 0 0 1680 17224 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity 0.999999999967141 -3.28586388146187e-11 7 0 0 1680 17224 GO:0008559 xenobiotic transmembrane transporting ATPase activity 0.999999999967141 -3.28586388146187e-11 7 0 0 1680 17224 GO:0016433 rRNA (adenine) methyltransferase activity 0.999999999967141 -3.28586388146187e-11 7 0 0 1680 17224 GO:0031701 angiotensin receptor binding 0.999999999967141 -3.28586388146187e-11 7 0 0 1680 17224 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving 0.999999999967141 -3.28586388146187e-11 7 0 0 1680 17224 GO:0051998 protein carboxyl O-methyltransferase activity 0.999999999967141 -3.28586388146187e-11 7 0 0 1680 17224 GO:0051185 coenzyme transmembrane transporter activity 0.999999999967141 -3.28586388146187e-11 7 0 0 1680 17224 GO:0030911 TPR domain binding 0.999999999967141 -3.28586388146187e-11 7 0 0 1680 17224 GO:0036374 glutathione hydrolase activity 0.999999999967141 -3.28586388146187e-11 7 0 0 1680 17224 GO:0019870 potassium channel inhibitor activity 0.999999999967141 -3.28586388146187e-11 7 0 0 1680 17224 GO:0047134 protein-disulfide reductase activity 0.999999999967141 -3.28586388146187e-11 7 0 0 1680 17224 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity 0.999999999967141 -3.28586388146187e-11 7 0 0 1680 17224 GO:0003747 translation release factor activity 0.999999999967141 -3.28586388146187e-11 7 0 0 1680 17224 GO:0004568 chitinase activity 0.999999999967141 -3.28586388146187e-11 7 0 0 1680 17224 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity 0.999999999967141 -3.28586388146187e-11 7 0 0 1680 17224 GO:0010340 carboxyl-O-methyltransferase activity 0.999999999967141 -3.28586388146187e-11 7 0 0 1680 17224 GO:0008479 queuine tRNA-ribosyltransferase activity 0.999999999967141 -3.28586388146187e-11 7 0 0 1680 17224 GO:0008318 protein prenyltransferase activity 0.999999999967141 -3.28586388146187e-11 7 0 0 1680 17224 GO:0070990 snRNP binding 0.999999999967141 -3.28586388146187e-11 7 0 0 1680 17224 GO:0005138 interleukin-6 receptor binding 0.999999999967141 -3.28586388146187e-11 7 0 0 1680 17224 GO:0003916 DNA topoisomerase activity 0.999999999967141 -3.28586388146187e-11 7 0 0 1680 17224 GO:0001758 retinal dehydrogenase activity 0.999999999967141 -3.28586388146187e-11 7 0 0 1680 17224 GO:0008079 translation termination factor activity 0.999999999967141 -3.28586388146187e-11 7 0 0 1680 17224 GO:0034235 GPI anchor binding 0.999999999967141 -3.28586388146187e-11 7 0 0 1680 17224 GO:0004301 epoxide hydrolase activity 0.999999999967141 -3.28586388146187e-11 7 0 0 1680 17224 GO:0010853 cyclase activator activity 0.999999999967141 -3.28586388146187e-11 7 0 0 1680 17224 GO:0005131 growth hormone receptor binding 0.999999999967141 -3.28586388146187e-11 7 0 0 1680 17224 GO:0034046 poly(G) binding 0.999999999967141 -3.28586388146187e-11 7 0 0 1680 17224 GO:0015252 proton channel activity 0.999999999967141 -3.28586388146187e-11 7 0 0 1680 17224 GO:0070569 uridylyltransferase activity 0.999999999967141 -3.28586388146187e-11 7 0 0 1680 17224 GO:0008312 7S RNA binding 0.999999999967141 -3.28586388146187e-11 7 0 0 1680 17224 GO:0070324 thyroid hormone binding 0.999999999967141 -3.28586388146187e-11 7 0 0 1680 17224 GO:0047844 deoxycytidine deaminase activity 0.999999999967141 -3.28586388146187e-11 7 0 0 1680 17224 GO:0005223 intracellular cGMP activated cation channel activity 0.999999999967141 -3.28586388146187e-11 7 0 0 1680 17224 GO:0031433 telethonin binding 0.999999999967141 -3.28586388146187e-11 7 0 0 1680 17224 GO:0030250 guanylate cyclase activator activity 0.999999999967141 -3.28586388146187e-11 7 0 0 1680 17224 GO:0001016 RNA polymerase III regulatory region DNA binding 0.999999999967141 -3.28586388146187e-11 7 0 0 1680 17224 GO:0003909 DNA ligase activity 0.999999999967141 -3.28586388146187e-11 7 0 0 1680 17224 GO:0097322 7SK snRNA binding 0.999999999967141 -3.28586388146187e-11 7 0 0 1680 17224 GO:0015204 urea transmembrane transporter activity 0.999999999967141 -3.28586388146187e-11 7 0 0 1680 17224 GO:1990247 N6-methyladenosine-containing RNA binding 0.999999999967141 -3.28586388146187e-11 7 0 0 1680 17224 GO:0005337 nucleoside transmembrane transporter activity 0.999999999967141 -3.28586388146187e-11 7 0 0 1680 17224 GO:0043140 ATP-dependent 3'-5' DNA helicase activity 0.999999999967141 -3.28586388146187e-11 7 0 0 1680 17224 GO:0004887 thyroid hormone receptor activity 0.999999999967141 -3.28586388146187e-11 7 0 0 1680 17224 GO:0022850 serotonin-gated cation-selective channel activity 0.999999999967141 -3.28586388146187e-11 7 0 0 1680 17224 GO:0015226 carnitine transmembrane transporter activity 0.999999999967141 -3.28586388146187e-11 7 0 0 1680 17224 GO:0015220 choline transmembrane transporter activity 0.999999999967141 -3.28586388146187e-11 7 0 0 1680 17224 GO:0015321 sodium-dependent phosphate transmembrane transporter activity 0.999999999967141 -3.28586388146187e-11 7 0 0 1680 17224 GO:0017160 Ral GTPase binding 0.999999999975154 -2.48457812349001e-11 16 0 0 1680 17224 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity 0.999999999975154 -2.48457812349001e-11 16 0 0 1680 17224 GO:0048038 quinone binding 0.999999999975154 -2.48457812349001e-11 16 0 0 1680 17224 GO:0016918 retinal binding 0.999999999975154 -2.48457812349001e-11 16 0 0 1680 17224 GO:0004549 tRNA-specific ribonuclease activity 0.999999999975154 -2.48457812349001e-11 16 0 0 1680 17224 GO:0031386 protein tag 0.999999999975154 -2.48457812349001e-11 16 0 0 1680 17224 GO:0005372 water transmembrane transporter activity 0.999999999975154 -2.48457812349001e-11 16 0 0 1680 17224 GO:0000400 four-way junction DNA binding 0.999999999975154 -2.48457812349001e-11 16 0 0 1680 17224 GO:0005159 insulin-like growth factor receptor binding 0.999999999975154 -2.48457812349001e-11 16 0 0 1680 17224 GO:0003995 acyl-CoA dehydrogenase activity 0.999999999975154 -2.48457812349001e-11 16 0 0 1680 17224 GO:0005149 interleukin-1 receptor binding 0.999999999975154 -2.48457812349001e-11 16 0 0 1680 17224 GO:0001091 RNA polymerase II basal transcription factor binding 0.999999999975154 -2.48457812349001e-11 16 0 0 1680 17224 GO:0017136 NAD-dependent histone deacetylase activity 0.999999999975154 -2.48457812349001e-11 16 0 0 1680 17224 GO:0097153 cysteine-type endopeptidase activity involved in apoptotic process 0.999999999975154 -2.48457812349001e-11 16 0 0 1680 17224 GO:0003887 DNA-directed DNA polymerase activity 0.999999999976707 -2.32932084247152e-11 28 0 0 1680 17224 GO:0061631 ubiquitin conjugating enzyme activity 0.999999999976707 -2.32932084247152e-11 28 0 0 1680 17224 GO:0008188 neuropeptide receptor activity 0.99999999997898 -2.10195401124436e-11 51 0 0 1680 17224 GO:0015056 corticotrophin-releasing factor receptor activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0033041 sweet taste receptor activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0031780 corticotropin hormone receptor binding 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0016657 oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0004657 proline dehydrogenase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0016501 prostacyclin receptor activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0052593 tryptamine:oxygen oxidoreductase (deaminating) activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0008650 rRNA (uridine-2'-O-)-methyltransferase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0016534 cyclin-dependent protein kinase 5 activator activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0004905 type I interferon receptor activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:1990698 palmitoleoyltransferase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0004818 glutamate-tRNA ligase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0004793 threonine aldolase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0045550 geranylgeranyl reductase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0001735 prenylcysteine oxidase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0004088 carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0015227 acyl carnitine transmembrane transporter activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0000215 tRNA 2'-phosphotransferase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0042020 interleukin-23 receptor activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0015218 pyrimidine nucleotide transmembrane transporter activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0015391 nucleobase:cation symporter activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0005171 hepatocyte growth factor receptor binding 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:1902271 D3 vitamins binding 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0045029 UDP-activated nucleotide receptor activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0004874 aryl hydrocarbon receptor activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0008988 rRNA (adenine-N6-)-methyltransferase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0046922 peptide-O-fucosyltransferase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0015432 bile acid-exporting ATPase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:2001065 mannan binding 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0036009 protein-glutamine N-methyltransferase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0047017 prostaglandin-F synthase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0052852 very-long-chain-(S)-2-hydroxy-acid oxidase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0033680 ATP-dependent DNA/RNA helicase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0005153 interleukin-8 receptor binding 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0016608 growth hormone-releasing hormone activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0005046 KDEL sequence binding 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0004823 leucine-tRNA ligase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0047006 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0004157 dihydropyrimidinase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0001607 neuromedin U receptor activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0034739 histone deacetylase activity (H4-K16 specific) 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0003914 DNA (6-4) photolyase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0004781 sulfate adenylyltransferase (ATP) activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0000048 peptidyltransferase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0070336 flap-structured DNA binding 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0019981 interleukin-6 binding 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0009882 blue light photoreceptor activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0004103 choline kinase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0031127 alpha-(1,2)-fucosyltransferase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0052654 L-leucine transaminase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0070735 protein-glycine ligase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0005146 leukemia inhibitory factor receptor binding 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0004962 endothelin receptor activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0099038 ceramide-translocating ATPase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0004660 protein farnesyltransferase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0004356 glutamate-ammonia ligase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0033283 organic acid-transporting ATPase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0005457 GDP-fucose transmembrane transporter activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0031530 gonadotropin-releasing hormone receptor binding 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0032551 pyrimidine ribonucleoside binding 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0004067 asparaginase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0004609 phosphatidylserine decarboxylase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0032143 single thymine insertion binding 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0017057 6-phosphogluconolactonase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0070643 vitamin D 25-hydroxylase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0102521 tRNA-4-demethylwyosine synthase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0004070 aspartate carbamoyltransferase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0044620 ACP phosphopantetheine attachment site binding 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0032181 dinucleotide repeat insertion binding 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0004794 L-threonine ammonia-lyase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:2001070 starch binding 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0046997 oxidoreductase activity, acting on the CH-NH group of donors, flavin as acceptor 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0030627 pre-mRNA 5'-splice site binding 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0008389 coumarin 7-hydroxylase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0031894 V1A vasopressin receptor binding 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0005093 Rab GDP-dissociation inhibitor activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0102938 orcinol O-methyltransferase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0072545 tyrosine binding 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0052853 long-chain-(S)-2-hydroxy-long-chain-acid oxidase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0102751 UDP-alpha-D-glucose:glucosyl-glycogenin alpha-D-glucosyltransferase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0019948 SUMO activating enzyme activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0008520 L-ascorbate:sodium symporter activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0052655 L-valine transaminase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0003863 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0016716 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0003963 RNA-3'-phosphate cyclase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0034458 3'-5' RNA helicase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:1990404 protein ADP-ribosylase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0001632 leukotriene B4 receptor activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0008476 protein-tyrosine sulfotransferase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0000701 purine-specific mismatch base pair DNA N-glycosylase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0060072 large conductance calcium-activated potassium channel activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0004906 interferon-gamma receptor activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0016151 nickel cation binding 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0019107 myristoyltransferase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0098640 integrin binding involved in cell-matrix adhesion 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0005026 transforming growth factor beta receptor activity, type II 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0015927 trehalase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0008396 oxysterol 7-alpha-hydroxylase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0004958 prostaglandin F receptor activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0042019 interleukin-23 binding 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0004662 CAAX-protein geranylgeranyltransferase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0045519 interleukin-23 receptor binding 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0052869 arachidonic acid omega-hydroxylase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0071568 UFM1 transferase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0047787 delta4-3-oxosteroid 5beta-reductase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0035379 carbon dioxide transmembrane transporter activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0000036 acyl carrier activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0061547 glycogen synthase activity, transferring glucose-1-phosphate 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0008781 N-acylneuraminate cytidylyltransferase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0004373 glycogen (starch) synthase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0004991 parathyroid hormone receptor activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0001888 glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0071796 K6-linked polyubiquitin modification-dependent protein binding 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0031755 Edg-2 lysophosphatidic acid receptor binding 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0001604 urotensin II receptor activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0004963 follicle-stimulating hormone receptor activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0045155 electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:1905538 polysome binding 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0016649 oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0004756 selenide, water dikinase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0071885 N-terminal protein N-methyltransferase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0015140 malate transmembrane transporter activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0004831 tyrosine-tRNA ligase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0016499 orexin receptor activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0010698 acetyltransferase activator activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0004574 oligo-1,6-glucosidase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0016708 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of two atoms of oxygen into one donor 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0004416 hydroxyacylglutathione hydrolase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0004782 sulfinoalanine decarboxylase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0004382 guanosine-diphosphatase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0004577 N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0071074 eukaryotic initiation factor eIF2 binding 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0031403 lithium ion binding 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0102084 L-dopa O-methyltransferase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0003868 4-hydroxyphenylpyruvate dioxygenase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0030626 U12 snRNA binding 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0023025 MHC class Ib protein complex binding 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:1990190 peptide-glutamate-N-acetyltransferase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0008941 nitric oxide dioxygenase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0061809 NAD+ nucleotidase, cyclic ADP-ribose generating 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0034057 RNA strand-exchange activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0016263 glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0008260 3-oxoacid CoA-transferase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0022852 glycine-gated chloride ion channel activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0004951 cholecystokinin receptor activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0032394 MHC class Ib receptor activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0005148 prolactin receptor binding 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0004174 electron-transferring-flavoprotein dehydrogenase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0004372 glycine hydroxymethyltransferase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0004357 glutamate-cysteine ligase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0035514 DNA demethylase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0051765 inositol tetrakisphosphate kinase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0003826 alpha-ketoacid dehydrogenase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0098808 mRNA cap binding 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0018479 benzaldehyde dehydrogenase (NAD+) activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0004909 interleukin-1, Type I, activating receptor activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0052595 aliphatic-amine oxidase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0050613 delta14-sterol reductase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0004821 histidine-tRNA ligase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0001855 complement component C4b binding 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0004329 formate-tetrahydrofolate ligase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0034416 bisphosphoglycerate phosphatase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0004482 mRNA (guanine-N7-)-methyltransferase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0051800 phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0070538 oleic acid binding 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0031752 D5 dopamine receptor binding 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0008281 sulfonylurea receptor activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0016150 translation release factor activity, codon nonspecific 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0047150 betaine-homocysteine S-methyltransferase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0030354 melanin-concentrating hormone activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0097604 temperature-gated cation channel activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0070191 methionine-R-sulfoxide reductase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0004816 asparagine-tRNA ligase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0031732 CCR7 chemokine receptor binding 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0045142 triplex DNA binding 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0052656 L-isoleucine transaminase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0045518 interleukin-22 receptor binding 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0000703 oxidized pyrimidine nucleobase lesion DNA N-glycosylase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0009383 rRNA (cytosine-C5-)-methyltransferase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0016206 catechol O-methyltransferase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0008263 pyrimidine-specific mismatch base pair DNA N-glycosylase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0008732 L-allo-threonine aldolase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0015350 methotrexate transmembrane transporter activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0016749 N-succinyltransferase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0052871 alpha-tocopherol omega-hydroxylase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0097363 protein O-GlcNAc transferase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0004367 glycerol-3-phosphate dehydrogenase [NAD+] activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0004913 interleukin-4 receptor activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0017042 glycosylceramidase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0004027 alcohol sulfotransferase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0071886 1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine binding 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0047783 corticosterone 18-monooxygenase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0098770 FBXO family protein binding 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0032129 histone deacetylase activity (H3-K9 specific) 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0008113 peptide-methionine (S)-S-oxide reductase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0004998 transferrin receptor activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0003989 acetyl-CoA carboxylase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0038052 RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0008147 structural constituent of bone 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0016781 phosphotransferase activity, paired acceptors 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0004478 methionine adenosyltransferase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0005139 interleukin-7 receptor binding 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0035717 chemokine (C-C motif) ligand 7 binding 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0047179 platelet-activating factor acetyltransferase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0004140 dephospho-CoA kinase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0019781 NEDD8 activating enzyme activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0033906 hyaluronoglucuronidase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0045509 interleukin-27 receptor activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0090541 MIT domain binding 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0052901 spermine:oxygen oxidoreductase (spermidine-forming) activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0008107 galactoside 2-alpha-L-fucosyltransferase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0015636 short-chain fatty acid transmembrane transporter activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0001003 RNA polymerase III type 2 promoter sequence-specific DNA binding 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0004779 sulfate adenylyltransferase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0005166 neurotrophin p75 receptor binding 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0005135 interleukin-3 receptor binding 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0000992 polymerase III regulatory region sequence-specific DNA binding 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0060698 endoribonuclease inhibitor activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0004743 pyruvate kinase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0004912 interleukin-3 receptor activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0030366 molybdopterin synthase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0046969 NAD-dependent histone deacetylase activity (H3-K9 specific) 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0042132 fructose 1,6-bisphosphate 1-phosphatase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0072354 histone kinase activity (H3-T3 specific) 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0002951 leukotriene-C(4) hydrolase 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0005459 UDP-galactose transmembrane transporter activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0004105 choline-phosphate cytidylyltransferase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0033040 sour taste receptor activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0061769 ribosylnicotinate kinase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0004109 coproporphyrinogen oxidase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0004918 interleukin-8 receptor activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0051717 inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0004819 glutamine-tRNA ligase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0000406 double-strand/single-strand DNA junction binding 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0050509 N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0023030 MHC class Ib protein binding, via antigen binding groove 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0016492 G-protein coupled neurotensin receptor activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0016862 intramolecular oxidoreductase activity, interconverting keto- and enol-groups 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0070401 NADP+ binding 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0005183 gonadotropin hormone-releasing hormone activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0042284 sphingolipid delta-4 desaturase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0050436 microfibril binding 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0005174 CD40 receptor binding 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0047057 vitamin-K-epoxide reductase (warfarin-sensitive) activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0070052 collagen V binding 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0031699 beta-3 adrenergic receptor binding 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0050659 N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0008459 chondroitin 6-sulfotransferase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0003920 GMP reductase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0047804 cysteine-S-conjugate beta-lyase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0035718 macrophage migration inhibitory factor binding 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:1904768 all-trans-retinol binding 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0004557 alpha-galactosidase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0004822 isoleucine-tRNA ligase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0051192 prosthetic group binding 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0015203 polyamine transmembrane transporter activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0052856 NADHX epimerase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0052594 aminoacetone:oxygen oxidoreductase(deaminating) activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0015382 sodium:sulfate symporter activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0008967 phosphoglycolate phosphatase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0051139 metal ion:proton antiporter activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0008413 8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0008481 sphinganine kinase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0004087 carbamoyl-phosphate synthase (ammonia) activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0001018 mitochondrial promoter sequence-specific DNA binding 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0034632 retinol transmembrane transporter activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:1905502 acetyl-CoA binding 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0005137 interleukin-5 receptor binding 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0097258 20-hydroxy-leukotriene B4 omega oxidase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0008962 phosphatidylglycerophosphatase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0004946 bombesin receptor activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0047708 biotinidase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0005275 amine transmembrane transporter activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0003883 CTP synthase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0004063 aryldialkylphosphatase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0042835 BRE binding 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0061749 forked DNA-dependent helicase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0061711 N(6)-L-threonylcarbamoyladenine synthase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0000247 C-8 sterol isomerase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0018423 protein C-terminal leucine carboxyl O-methyltransferase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0051990 (R)-2-hydroxyglutarate dehydrogenase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0000384 first spliceosomal transesterification activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0016855 racemase and epimerase activity, acting on amino acids and derivatives 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0004392 heme oxygenase (decyclizing) activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0047661 amino-acid racemase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0102092 5-diphosphoinositol pentakisphosphate 3-kinase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0033570 transferrin transmembrane transporter activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0050119 N-acetylglucosamine deacetylase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0008746 NAD(P)+ transhydrogenase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0052857 NADPHX epimerase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0047977 hepoxilin-epoxide hydrolase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0047025 3-oxoacyl-[acyl-carrier-protein] reductase (NADH) activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0001165 RNA polymerase I upstream control element sequence-specific DNA binding 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0004776 succinate-CoA ligase (GDP-forming) activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0016165 linoleate 13S-lipoxygenase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0015928 fucosidase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0004483 mRNA (nucleoside-2'-O-)-methyltransferase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0038131 neuregulin receptor activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0004335 galactokinase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0051021 GDP-dissociation inhibitor binding 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:1990259 histone-glutamine methyltransferase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0038049 transcription factor activity, ligand-activated RNA polymerase II transcription factor binding 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0045145 single-stranded DNA 5'-3' exodeoxyribonuclease activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0035373 chondroitin sulfate proteoglycan binding 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0019785 ISG15-specific protease activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0004531 deoxyribonuclease II activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0017129 triglyceride binding 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0030343 vitamin D3 25-hydroxylase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0031862 prostanoid receptor binding 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0015182 L-asparagine transmembrane transporter activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0090555 phosphatidylethanolamine-translocating ATPase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0004530 deoxyribonuclease I activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0019912 cyclin-dependent protein kinase activating kinase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0008193 tRNA guanylyltransferase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0033285 monocarboxylic acid-transporting ATPase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0003943 N-acetylgalactosamine-4-sulfatase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0001026 TFIIIB-type transcription factor activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0061752 telomeric repeat-containing RNA binding 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0004915 interleukin-6 receptor activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0070180 large ribosomal subunit rRNA binding 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0102294 cholesterol dehydrogenase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0035870 dITP diphosphatase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0005308 creatine transmembrane transporter activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0016415 octanoyltransferase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0035800 deubiquitinase activator activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0004161 dimethylallyltranstransferase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0002134 UTP binding 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0004615 phosphomannomutase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0004345 glucose-6-phosphate dehydrogenase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0003870 5-aminolevulinate synthase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0003938 IMP dehydrogenase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0005011 macrophage colony-stimulating factor receptor activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0045523 interleukin-27 receptor binding 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0070890 sodium-dependent L-ascorbate transmembrane transporter activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0004850 uridine phosphorylase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0004368 glycerol-3-phosphate dehydrogenase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0004651 polynucleotide 5'-phosphatase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0052854 medium-chain-(S)-2-hydroxy-acid oxidase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0032038 myosin II heavy chain binding 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0004419 hydroxymethylglutaryl-CoA lyase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0052642 lysophosphatidic acid phosphatase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0034512 box C/D snoRNA binding 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0004750 ribulose-phosphate 3-epimerase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0050178 phenylpyruvate tautomerase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0050347 trans-octaprenyltranstransferase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0052816 long-chain acyl-CoA hydrolase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0017050 D-erythro-sphingosine kinase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0015389 pyrimidine- and adenine-specific:sodium symporter activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0070080 titin Z domain binding 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0050497 transferase activity, transferring alkylthio groups 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0004337 geranyltranstransferase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0004815 aspartate-tRNA ligase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0052596 phenethylamine:oxygen oxidoreductase (deaminating) activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0032977 membrane insertase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0047196 long-chain-alcohol O-fatty-acyltransferase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0004727 prenylated protein tyrosine phosphatase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0071207 histone pre-mRNA stem-loop binding 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0052870 tocopherol omega-hydroxylase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0090556 phosphatidylserine-translocating ATPase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0004828 serine-tRNA ligase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0004137 deoxycytidine kinase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0017130 poly(C) RNA binding 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0050135 NAD(P)+ nucleosidase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0008441 3'(2'),5'-bisphosphate nucleotidase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0015665 alcohol transmembrane transporter activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0019972 interleukin-12 binding 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0004914 interleukin-5 receptor activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0030283 testosterone dehydrogenase [NAD(P)] activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0003913 DNA photolyase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0103095 wax ester synthase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0015087 cobalt ion transmembrane transporter activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0052815 medium-chain acyl-CoA hydrolase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0033149 FFAT motif binding 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0034039 8-oxo-7,8-dihydroguanine DNA N-glycosylase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0004775 succinate-CoA ligase (ADP-forming) activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0042781 3'-tRNA processing endoribonuclease activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0070780 dihydrosphingosine-1-phosphate phosphatase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0031783 type 5 melanocortin receptor binding 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:1904455 ubiquitin-specific protease activity involved in negative regulation of ERAD pathway 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0033284 carboxylic acid-transporting ATPase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0016726 oxidoreductase activity, acting on CH or CH2 groups, NAD or NADP as acceptor 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0031711 bradykinin receptor binding 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0005185 neurohypophyseal hormone activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0004352 glutamate dehydrogenase (NAD+) activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0046964 3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0004878 complement component C5a receptor activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0001884 pyrimidine nucleoside binding 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0004555 alpha,alpha-trehalase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0005055 laminin receptor activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0070506 high-density lipoprotein particle receptor activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0071791 chemokine (C-C motif) ligand 5 binding 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0008124 4-alpha-hydroxytetrahydrobiopterin dehydratase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0034188 apolipoprotein A-I receptor activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0005503 all-trans retinal binding 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0001002 RNA polymerase III type 1 promoter sequence-specific DNA binding 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0015489 putrescine transmembrane transporter activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0004666 prostaglandin-endoperoxide synthase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0010736 serum response element binding 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0033883 pyridoxal phosphatase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0070012 oligopeptidase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0004379 glycylpeptide N-tetradecanoyltransferase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0019144 ADP-sugar diphosphatase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0001224 RNA polymerase II transcription cofactor binding 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0044378 non-sequence-specific DNA binding, bending 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:1990269 RNA polymerase II C-terminal domain phosphoserine binding 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0008545 JUN kinase kinase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0003904 deoxyribodipyrimidine photo-lyase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0036361 racemase activity, acting on amino acids and derivatives 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0002094 polyprenyltransferase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0016900 oxidoreductase activity, acting on the CH-OH group of donors, disulfide as acceptor 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0043183 vascular endothelial growth factor receptor 1 binding 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0000171 ribonuclease MRP activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0004031 aldehyde oxidase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0008311 double-stranded DNA 3'-5' exodeoxyribonuclease activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0016890 site-specific endodeoxyribonuclease activity, specific for altered base 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0005362 low-affinity glucose:sodium symporter activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0001785 prostaglandin J receptor activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0052810 1-phosphatidylinositol-5-kinase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0005228 intracellular sodium activated potassium channel activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0001160 transcription termination site DNA binding 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0004450 isocitrate dehydrogenase (NADP+) activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0015230 FAD transmembrane transporter activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0015229 L-ascorbic acid transmembrane transporter activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0004956 prostaglandin D receptor activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0004447 iodide peroxidase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0000010 trans-hexaprenyltranstransferase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0004667 prostaglandin-D synthase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0071567 UFM1 hydrolase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0016652 oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0004360 glutamine-fructose-6-phosphate transaminase (isomerizing) activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0032090 Pyrin domain binding 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0001729 ceramide kinase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0097003 adipokinetic hormone receptor activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0004649 poly(ADP-ribose) glycohydrolase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0035539 8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0036080 purine nucleotide-sugar transmembrane transporter activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0004353 glutamate dehydrogenase [NAD(P)+] activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0051499 D-aminoacyl-tRNA deacylase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0044715 8-oxo-dGDP phosphatase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0033857 diphosphoinositol-pentakisphosphate kinase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0033754 indoleamine 2,3-dioxygenase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0016005 phospholipase A2 activator activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0016901 oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0035596 methylthiotransferase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0005151 interleukin-1, Type II receptor binding 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0001147 transcription termination site sequence-specific DNA binding 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0010465 nerve growth factor receptor activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0042281 dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0004020 adenylylsulfate kinase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0004618 phosphoglycerate kinase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0004485 methylcrotonoyl-CoA carboxylase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0004854 xanthine dehydrogenase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0004053 arginase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0046592 polyamine oxidase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:1990932 5.8S rRNA binding 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0061714 folic acid receptor activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0052740 1-acyl-2-lysophosphatidylserine acylhydrolase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0003998 acylphosphatase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0008176 tRNA (guanine-N7-)-methyltransferase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0001181 transcription factor activity, core RNA polymerase I binding 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0001641 group II metabotropic glutamate receptor activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0099609 microtubule lateral binding 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0001069 regulatory region RNA binding 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:1904854 proteasome core complex binding 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0097259 20-aldehyde-leukotriene B4 20-monooxygenase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0019777 Atg12 transferase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0004910 interleukin-1, Type II, blocking receptor activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0003948 N4-(beta-N-acetylglucosaminyl)-L-asparaginase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0004947 bradykinin receptor activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0004047 aminomethyltransferase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0099530 G-protein coupled receptor activity involved in regulation of postsynaptic membrane potential 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0051500 D-tyrosyl-tRNA(Tyr) deacylase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0042924 neuromedin U binding 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0102966 arachidoyl-CoA:1-dodecanol O-acyltransferase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0004507 steroid 11-beta-monooxygenase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0034986 iron chaperone activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0004917 interleukin-7 receptor activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0005462 UDP-N-acetylglucosamine transmembrane transporter activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0070259 tyrosyl-DNA phosphodiesterase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0008251 tRNA-specific adenosine deaminase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:1905573 ganglioside GM1 binding 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0016211 ammonia ligase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0004560 alpha-L-fucosidase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0050253 retinyl-palmitate esterase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0004572 mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0090422 thiamine pyrophosphate transmembrane transporter activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0051022 Rho GDP-dissociation inhibitor binding 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0008466 glycogenin glucosyltransferase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0103053 1-ethyladenine demethylase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0003884 D-amino-acid oxidase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0004658 propionyl-CoA carboxylase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0035500 MH2 domain binding 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0004342 glucosamine-6-phosphate deaminase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0031826 type 2A serotonin receptor binding 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0030337 DNA polymerase processivity factor activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0086059 voltage-gated calcium channel activity involved SA node cell action potential 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0019961 interferon binding 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0004797 thymidine kinase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0004873 asialoglycoprotein receptor activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0004084 branched-chain-amino-acid transaminase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0035034 histone acetyltransferase regulator activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0050262 ribosylnicotinamide kinase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0008269 JAK pathway signal transduction adaptor activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0042903 tubulin deacetylase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0019770 IgG receptor activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0004510 tryptophan 5-monooxygenase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0016230 sphingomyelin phosphodiesterase activator activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0031753 endothelial differentiation G-protein coupled receptor binding 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0003980 UDP-glucose:glycoprotein glucosyltransferase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0031696 alpha-2C adrenergic receptor binding 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0052827 inositol pentakisphosphate phosphatase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0030549 acetylcholine receptor activator activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0048257 3'-flap endonuclease activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0050698 proteoglycan sulfotransferase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0004151 dihydroorotase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0004119 cGMP-inhibited cyclic-nucleotide phosphodiesterase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0003977 UDP-N-acetylglucosamine diphosphorylase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0004304 estrone sulfotransferase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:0004170 dUTP diphosphatase activity 0.999999999979202 -2.07979241467759e-11 2 0 0 1680 17224 GO:1903231 mRNA binding involved in posttranscriptional gene silencing 0.999999999979325 -2.06751621830227e-11 199 0 0 1680 17224 GO:0042289 MHC class II protein binding 0.999999999979605 -2.03946017338694e-11 6 0 0 1680 17224 GO:0047086 ketosteroid monooxygenase activity 0.999999999979605 -2.03946017338694e-11 6 0 0 1680 17224 GO:0008422 beta-glucosidase activity 0.999999999979605 -2.03946017338694e-11 6 0 0 1680 17224 GO:1990226 histone methyltransferase binding 0.999999999979605 -2.03946017338694e-11 6 0 0 1680 17224 GO:0036402 proteasome-activating ATPase activity 0.999999999979605 -2.03946017338694e-11 6 0 0 1680 17224 GO:0034481 chondroitin sulfotransferase activity 0.999999999979605 -2.03946017338694e-11 6 0 0 1680 17224 GO:0016421 CoA carboxylase activity 0.999999999979605 -2.03946017338694e-11 6 0 0 1680 17224 GO:0035312 5'-3' exodeoxyribonuclease activity 0.999999999979605 -2.03946017338694e-11 6 0 0 1680 17224 GO:0034603 pyruvate dehydrogenase [NAD(P)+] activity 0.999999999979605 -2.03946017338694e-11 6 0 0 1680 17224 GO:0015288 porin activity 0.999999999979605 -2.03946017338694e-11 6 0 0 1680 17224 GO:0008508 bile acid:sodium symporter activity 0.999999999979605 -2.03946017338694e-11 6 0 0 1680 17224 GO:0051766 inositol trisphosphate kinase activity 0.999999999979605 -2.03946017338694e-11 6 0 0 1680 17224 GO:0036435 K48-linked polyubiquitin modification-dependent protein binding 0.999999999979605 -2.03946017338694e-11 6 0 0 1680 17224 GO:0042979 ornithine decarboxylase regulator activity 0.999999999979605 -2.03946017338694e-11 6 0 0 1680 17224 GO:0016724 oxidoreductase activity, oxidizing metal ions, oxygen as acceptor 0.999999999979605 -2.03946017338694e-11 6 0 0 1680 17224 GO:0055105 ubiquitin-protein transferase inhibitor activity 0.999999999979605 -2.03946017338694e-11 6 0 0 1680 17224 GO:0004322 ferroxidase activity 0.999999999979605 -2.03946017338694e-11 6 0 0 1680 17224 GO:0032135 DNA insertion or deletion binding 0.999999999979605 -2.03946017338694e-11 6 0 0 1680 17224 GO:0005345 purine nucleobase transmembrane transporter activity 0.999999999979605 -2.03946017338694e-11 6 0 0 1680 17224 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity 0.999999999979605 -2.03946017338694e-11 6 0 0 1680 17224 GO:0004565 beta-galactosidase activity 0.999999999979605 -2.03946017338694e-11 6 0 0 1680 17224 GO:0047035 testosterone dehydrogenase (NAD+) activity 0.999999999979605 -2.03946017338694e-11 6 0 0 1680 17224 GO:0004024 alcohol dehydrogenase activity, zinc-dependent 0.999999999979605 -2.03946017338694e-11 6 0 0 1680 17224 GO:0034190 apolipoprotein receptor binding 0.999999999979605 -2.03946017338694e-11 6 0 0 1680 17224 GO:0003988 acetyl-CoA C-acyltransferase activity 0.999999999979605 -2.03946017338694e-11 6 0 0 1680 17224 GO:0004738 pyruvate dehydrogenase activity 0.999999999979605 -2.03946017338694e-11 6 0 0 1680 17224 GO:0001631 cysteinyl leukotriene receptor activity 0.999999999979605 -2.03946017338694e-11 6 0 0 1680 17224 GO:0004035 alkaline phosphatase activity 0.999999999979605 -2.03946017338694e-11 6 0 0 1680 17224 GO:0034604 pyruvate dehydrogenase (NAD+) activity 0.999999999979605 -2.03946017338694e-11 6 0 0 1680 17224 GO:0005329 dopamine transmembrane transporter activity 0.999999999979605 -2.03946017338694e-11 6 0 0 1680 17224 GO:0016406 carnitine O-acyltransferase activity 0.999999999979605 -2.03946017338694e-11 6 0 0 1680 17224 GO:0015168 glycerol transmembrane transporter activity 0.999999999979605 -2.03946017338694e-11 6 0 0 1680 17224 GO:0016635 oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor 0.999999999979605 -2.03946017338694e-11 6 0 0 1680 17224 GO:0016997 alpha-sialidase activity 0.999999999979605 -2.03946017338694e-11 6 0 0 1680 17224 GO:0030628 pre-mRNA 3'-splice site binding 0.999999999979605 -2.03946017338694e-11 6 0 0 1680 17224 GO:0016160 amylase activity 0.999999999979605 -2.03946017338694e-11 6 0 0 1680 17224 GO:0030621 U4 snRNA binding 0.999999999979605 -2.03946017338694e-11 6 0 0 1680 17224 GO:0019958 C-X-C chemokine binding 0.999999999979605 -2.03946017338694e-11 6 0 0 1680 17224 GO:0032405 MutLalpha complex binding 0.999999999979605 -2.03946017338694e-11 6 0 0 1680 17224 GO:0003910 DNA ligase (ATP) activity 0.999999999979605 -2.03946017338694e-11 6 0 0 1680 17224 GO:0004111 creatine kinase activity 0.999999999979605 -2.03946017338694e-11 6 0 0 1680 17224 GO:0019788 NEDD8 transferase activity 0.999999999979605 -2.03946017338694e-11 6 0 0 1680 17224 GO:0031731 CCR6 chemokine receptor binding 0.999999999979605 -2.03946017338694e-11 6 0 0 1680 17224 GO:0004308 exo-alpha-sialidase activity 0.999999999979605 -2.03946017338694e-11 6 0 0 1680 17224 GO:0051400 BH domain binding 0.999999999979605 -2.03946017338694e-11 6 0 0 1680 17224 GO:0016435 rRNA (guanine) methyltransferase activity 0.999999999979605 -2.03946017338694e-11 6 0 0 1680 17224 GO:0055131 C3HC4-type RING finger domain binding 0.999999999979605 -2.03946017338694e-11 6 0 0 1680 17224 GO:0004974 leukotriene receptor activity 0.999999999979605 -2.03946017338694e-11 6 0 0 1680 17224 GO:0001602 pancreatic polypeptide receptor activity 0.999999999979605 -2.03946017338694e-11 6 0 0 1680 17224 GO:0019237 centromeric DNA binding 0.999999999979605 -2.03946017338694e-11 6 0 0 1680 17224 GO:0050693 LBD domain binding 0.999999999979605 -2.03946017338694e-11 6 0 0 1680 17224 GO:0003997 acyl-CoA oxidase activity 0.999999999979605 -2.03946017338694e-11 6 0 0 1680 17224 GO:0061133 endopeptidase activator activity 0.999999999979605 -2.03946017338694e-11 6 0 0 1680 17224 GO:0047499 calcium-independent phospholipase A2 activity 0.999999999979605 -2.03946017338694e-11 6 0 0 1680 17224 GO:0005412 glucose:sodium symporter activity 0.999999999979605 -2.03946017338694e-11 6 0 0 1680 17224 GO:0008432 JUN kinase binding 0.999999999979605 -2.03946017338694e-11 6 0 0 1680 17224 GO:0060228 phosphatidylcholine-sterol O-acyltransferase activator activity 0.999999999979605 -2.03946017338694e-11 6 0 0 1680 17224 GO:0015373 anion:sodium symporter activity 0.999999999979605 -2.03946017338694e-11 6 0 0 1680 17224 GO:0098988 G-protein coupled glutamate receptor activity 0.999999999979605 -2.03946017338694e-11 6 0 0 1680 17224 GO:0001640 adenylate cyclase inhibiting G-protein coupled glutamate receptor activity 0.999999999979605 -2.03946017338694e-11 6 0 0 1680 17224 GO:0042975 peroxisome proliferator activated receptor binding 0.999999999979605 -2.03946017338694e-11 6 0 0 1680 17224 GO:0005168 neurotrophin TRKA receptor binding 0.999999999979605 -2.03946017338694e-11 6 0 0 1680 17224 GO:0004430 1-phosphatidylinositol 4-kinase activity 0.999999999979605 -2.03946017338694e-11 6 0 0 1680 17224 GO:0004977 melanocortin receptor activity 0.999999999979605 -2.03946017338694e-11 6 0 0 1680 17224 GO:0004936 alpha-adrenergic receptor activity 0.999999999979605 -2.03946017338694e-11 6 0 0 1680 17224 GO:0000403 Y-form DNA binding 0.999999999979605 -2.03946017338694e-11 6 0 0 1680 17224 GO:0048039 ubiquinone binding 0.999999999979605 -2.03946017338694e-11 6 0 0 1680 17224 GO:0043546 molybdopterin cofactor binding 0.999999999979605 -2.03946017338694e-11 6 0 0 1680 17224 GO:0052658 inositol-1,4,5-trisphosphate 5-phosphatase activity 0.999999999979605 -2.03946017338694e-11 6 0 0 1680 17224 GO:1990405 protein antigen binding 0.999999999979605 -2.03946017338694e-11 6 0 0 1680 17224 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor 0.999999999979605 -2.03946017338694e-11 6 0 0 1680 17224 GO:0070087 chromo shadow domain binding 0.999999999979605 -2.03946017338694e-11 6 0 0 1680 17224 GO:0015129 lactate transmembrane transporter activity 0.999999999979605 -2.03946017338694e-11 6 0 0 1680 17224 GO:0001042 RNA polymerase I core binding 0.999999999979605 -2.03946017338694e-11 6 0 0 1680 17224 GO:0004704 NF-kappaB-inducing kinase activity 0.999999999979605 -2.03946017338694e-11 6 0 0 1680 17224 GO:0030274 LIM domain binding 0.999999999979605 -2.03946017338694e-11 6 0 0 1680 17224 GO:0010997 anaphase-promoting complex binding 0.999999999979605 -2.03946017338694e-11 6 0 0 1680 17224 GO:0004523 RNA-DNA hybrid ribonuclease activity 0.999999999979605 -2.03946017338694e-11 6 0 0 1680 17224 GO:0019238 cyclohydrolase activity 0.999999999979605 -2.03946017338694e-11 6 0 0 1680 17224 GO:0003846 2-acylglycerol O-acyltransferase activity 0.999999999979605 -2.03946017338694e-11 6 0 0 1680 17224 GO:0005384 manganese ion transmembrane transporter activity 0.999999999979605 -2.03946017338694e-11 6 0 0 1680 17224 GO:0031491 nucleosome binding 0.999999999981872 -1.81280620577159e-11 69 0 0 1680 17224 GO:0032450 maltose alpha-glucosidase activity 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:1990715 mRNA CDS binding 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0016802 trialkylsulfonium hydrolase activity 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0030369 ICAM-3 receptor activity 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0031531 thyrotropin-releasing hormone receptor binding 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0004534 5'-3' exoribonuclease activity 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0001097 TFIIH-class transcription factor binding 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0047288 monosialoganglioside sialyltransferase activity 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0052812 phosphatidylinositol-3,4-bisphosphate 5-kinase activity 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0000035 acyl binding 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0032557 pyrimidine ribonucleotide binding 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0004769 steroid delta-isomerase activity 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0031708 endothelin B receptor binding 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0015207 adenine transmembrane transporter activity 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0004370 glycerol kinase activity 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0055100 adiponectin binding 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0004911 interleukin-2 receptor activity 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0004832 valine-tRNA ligase activity 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0004938 alpha2-adrenergic receptor activity 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0071553 G-protein coupled pyrimidinergic nucleotide receptor activity 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0015319 sodium:inorganic phosphate symporter activity 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0052839 inositol diphosphate tetrakisphosphate kinase activity 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0008670 2,4-dienoyl-CoA reductase (NADPH) activity 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0005471 ATP:ADP antiporter activity 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0008240 tripeptidyl-peptidase activity 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0061731 ribonucleoside-diphosphate reductase activity 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0004473 malate dehydrogenase (decarboxylating) (NADP+) activity 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0047237 glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0102148 N-acetyl-beta-D-galactosaminidase activity 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0032558 adenyl deoxyribonucleotide binding 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0017116 single-stranded DNA-dependent ATP-dependent DNA helicase activity 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0004487 methylenetetrahydrofolate dehydrogenase (NAD+) activity 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0004809 tRNA (guanine-N2-)-methyltransferase activity 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0008940 nitrate reductase activity 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0035614 snRNA stem-loop binding 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0003880 protein C-terminal carboxyl O-methyltransferase activity 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0031493 nucleosomal histone binding 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0043262 adenosine-diphosphatase activity 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0005415 nucleoside:sodium symporter activity 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0015111 iodide transmembrane transporter activity 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0004145 diamine N-acetyltransferase activity 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0004980 melanocyte-stimulating hormone receptor activity 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0005152 interleukin-1 receptor antagonist activity 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0019797 procollagen-proline 3-dioxygenase activity 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0031871 proteinase activated receptor binding 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0008184 glycogen phosphorylase activity 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0008900 potassium:proton exchanging ATPase activity 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0016822 hydrolase activity, acting on acid carbon-carbon bonds 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0016262 protein N-acetylglucosaminyltransferase activity 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0016509 long-chain-3-hydroxyacyl-CoA dehydrogenase activity 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0015433 peptide antigen-transporting ATPase activity 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:1990460 leptin receptor binding 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0016402 pristanoyl-CoA oxidase activity 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0004146 dihydrofolate reductase activity 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0016422 mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0008321 Ral guanyl-nucleotide exchange factor activity 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0047894 flavonol 3-sulfotransferase activity 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0004167 dopachrome isomerase activity 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0097177 mitochondrial ribosome binding 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0005128 erythropoietin receptor binding 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0004886 9-cis retinoic acid receptor activity 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0015141 succinate transmembrane transporter activity 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0070644 vitamin D response element binding 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0008431 vitamin E binding 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0004999 vasoactive intestinal polypeptide receptor activity 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0042978 ornithine decarboxylase activator activity 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0016743 carboxyl- or carbamoyltransferase activity 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:1905576 ganglioside GT1b binding 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0019959 interleukin-8 binding 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0051377 mannose-ethanolamine phosphotransferase activity 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0003886 DNA (cytosine-5-)-methyltransferase activity 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0019166 trans-2-enoyl-CoA reductase (NADPH) activity 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0070186 growth hormone activity 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0003829 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0004346 glucose-6-phosphatase activity 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0061849 telomeric G-quadruplex DNA binding 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0070653 high-density lipoprotein particle receptor binding 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:2001069 glycogen binding 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0008428 ribonuclease inhibitor activity 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0036132 13-prostaglandin reductase activity 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0070138 ubiquitin-like protein-specific isopeptidase activity 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0047045 testosterone 17-beta-dehydrogenase (NADP+) activity 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0102250 linear malto-oligosaccharide phosphorylase activity 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0004829 threonine-tRNA ligase activity 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0000386 second spliceosomal transesterification activity 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0016532 superoxide dismutase copper chaperone activity 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0002950 ceramide phosphoethanolamine synthase activity 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0004307 ethanolaminephosphotransferase activity 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0005330 dopamine:sodium symporter activity 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0008169 C-methyltransferase activity 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0004075 biotin carboxylase activity 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0003896 DNA primase activity 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0030348 syntaxin-3 binding 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0003918 DNA topoisomerase type II (ATP-hydrolyzing) activity 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0016436 rRNA (uridine) methyltransferase activity 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0072510 trivalent inorganic cation transmembrane transporter activity 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0050265 RNA uridylyltransferase activity 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0005277 acetylcholine transmembrane transporter activity 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0015065 uridine nucleotide receptor activity 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0015247 aminophospholipid transmembrane transporter activity 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0015410 manganese-transporting ATPase activity 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0030226 apolipoprotein receptor activity 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0001601 peptide YY receptor activity 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0052739 phosphatidylserine 1-acylhydrolase activity 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0102007 acyl-L-homoserine-lactone lactonohydrolase activity 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0042134 rRNA primary transcript binding 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0004505 phenylalanine 4-monooxygenase activity 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0017077 oxidative phosphorylation uncoupler activity 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0070051 fibrinogen binding 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0000404 heteroduplex DNA loop binding 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0050692 DBD domain binding 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0002046 opsin binding 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0016941 natriuretic peptide receptor activity 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0051431 corticotropin-releasing hormone receptor 2 binding 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0030395 lactose binding 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0023024 MHC class I protein complex binding 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0061649 ubiquitin modification-dependent histone binding 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0004803 transposase activity 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0008073 ornithine decarboxylase inhibitor activity 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0009674 potassium:sodium symporter activity 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0043398 HLH domain binding 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:1990599 3' overhang single-stranded DNA endodeoxyribonuclease activity 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0015378 sodium:chloride symporter activity 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0003872 6-phosphofructokinase activity 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0045322 unmethylated CpG binding 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0032139 dinucleotide insertion or deletion binding 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0016748 succinyltransferase activity 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0005290 L-histidine transmembrane transporter activity 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0016434 rRNA (cytosine) methyltransferase activity 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0001025 RNA polymerase III transcription factor binding 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0004449 isocitrate dehydrogenase (NAD+) activity 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0030942 endoplasmic reticulum signal peptide binding 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0080122 AMP transmembrane transporter activity 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0004040 amidase activity 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0050254 rhodopsin kinase activity 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0097603 temperature-gated ion channel activity 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0032142 single guanine insertion binding 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0071077 adenosine 3',5'-bisphosphate transmembrane transporter activity 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0004949 cannabinoid receptor activity 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0008192 RNA guanylyltransferase activity 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0018636 phenanthrene 9,10-monooxygenase activity 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0017060 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0051734 ATP-dependent polynucleotide kinase activity 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0070095 fructose-6-phosphate binding 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0004359 glutaminase activity 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0003955 NAD(P)H dehydrogenase (quinone) activity 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0004348 glucosylceramidase activity 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0016823 hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0004586 ornithine decarboxylase activity 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0003973 (S)-2-hydroxy-acid oxidase activity 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0070140 SUMO-specific isopeptidase activity 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0047718 indanol dehydrogenase activity 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0016647 oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0004965 G-protein coupled GABA receptor activity 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0051870 methotrexate binding 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0038181 bile acid receptor activity 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0008449 N-acetylglucosamine-6-sulfatase activity 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0046404 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0004351 glutamate decarboxylase activity 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0004814 arginine-tRNA ligase activity 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0070905 serine binding 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0005483 soluble NSF attachment protein activity 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0003953 NAD+ nucleosidase activity 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0004052 arachidonate 12-lipoxygenase activity 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0015222 serotonin transmembrane transporter activity 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0003987 acetate-CoA ligase activity 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0004774 succinate-CoA ligase activity 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0070996 type 1 melanocortin receptor binding 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0004471 malate dehydrogenase (decarboxylating) (NAD+) activity 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0070548 L-glutamine aminotransferase activity 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0004882 androgen receptor activity 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0004968 gonadotropin-releasing hormone receptor activity 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0044323 retinoic acid-responsive element binding 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0047493 ceramide cholinephosphotransferase activity 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0004967 glucagon receptor activity 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0070039 rRNA (guanosine-2'-O-)-methyltransferase activity 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0004827 proline-tRNA ligase activity 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0050567 glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0003985 acetyl-CoA C-acetyltransferase activity 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0033188 sphingomyelin synthase activity 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:1990189 peptide-serine-N-acetyltransferase activity 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0071535 RING-like zinc finger domain binding 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0102499 SHG alpha-glucan phosphorylase activity 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0031692 alpha-1B adrenergic receptor binding 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0047223 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase activity 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0016623 oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0005333 norepinephrine transmembrane transporter activity 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0098518 polynucleotide phosphatase activity 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0000293 ferric-chelate reductase activity 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0030899 calcium-dependent ATPase activity 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0003941 L-serine ammonia-lyase activity 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0046573 lactonohydrolase activity 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0019826 oxygen sensor activity 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0070573 metallodipeptidase activity 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0034714 type III transforming growth factor beta receptor binding 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0046979 TAP2 binding 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0047522 15-oxoprostaglandin 13-oxidase activity 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0004995 tachykinin receptor activity 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0008513 secondary active organic cation transmembrane transporter activity 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0052836 inositol 5-diphosphate pentakisphosphate 5-kinase activity 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0050473 arachidonate 15-lipoxygenase activity 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0050309 sugar-terminal-phosphatase activity 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0005173 stem cell factor receptor binding 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0044729 hemi-methylated DNA-binding 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0001642 group III metabotropic glutamate receptor activity 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0001156 TFIIIC-class transcription factor binding 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0060230 lipoprotein lipase activator activity 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0030622 U4atac snRNA binding 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0004069 L-aspartate:2-oxoglutarate aminotransferase activity 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0004792 thiosulfate sulfurtransferase activity 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0004802 transketolase activity 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0019976 interleukin-2 binding 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0061505 DNA topoisomerase II activity 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0031893 vasopressin receptor binding 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0050252 retinol O-fatty-acyltransferase activity 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:1901375 acetate ester transmembrane transporter activity 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0030172 troponin C binding 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0061953 mRNA (adenine-N1-)-methyltransferase activity 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0031720 haptoglobin binding 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0015228 coenzyme A transmembrane transporter activity 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0015091 ferric iron transmembrane transporter activity 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0016639 oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:1903135 cupric ion binding 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0048403 brain-derived neurotrophic factor binding 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0004748 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0051733 polydeoxyribonucleotide kinase activity 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0005094 Rho GDP-dissociation inhibitor activity 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0031735 CCR10 chemokine receptor binding 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0004800 thyroxine 5'-deiodinase activity 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0016728 oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0004060 arylamine N-acetyltransferase activity 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0035276 ethanol binding 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0051120 hepoxilin A3 synthase activity 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0033677 DNA/RNA helicase activity 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0032399 HECT domain binding 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0015265 urea channel activity 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0003726 double-stranded RNA adenosine deaminase activity 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0004937 alpha1-adrenergic receptor activity 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:1905773 8-hydroxy-2'-deoxyguanosine DNA binding 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0004739 pyruvate dehydrogenase (acetyl-transferring) activity 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0008241 peptidyl-dipeptidase activity 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0004013 adenosylhomocysteinase activity 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0019809 spermidine binding 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0052735 tRNA (cytosine-3-)-methyltransferase activity 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0001093 TFIIB-class transcription factor binding 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0000033 alpha-1,3-mannosyltransferase activity 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0099583 neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0052905 tRNA (guanine(9)-N(1))-methyltransferase activity 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0030298 receptor signaling protein tyrosine kinase activator activity 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0032564 dATP binding 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0016880 acid-ammonia (or amide) ligase activity 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0031705 bombesin receptor binding 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0042015 interleukin-20 binding 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0008511 sodium:potassium:chloride symporter activity 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0070991 medium-chain-acyl-CoA dehydrogenase activity 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0099122 RNA polymerase II C-terminal domain binding 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0005350 pyrimidine nucleobase transmembrane transporter activity 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0016429 tRNA (adenine-N1-)-methyltransferase activity 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0051525 NFAT protein binding 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0070576 vitamin D 24-hydroxylase activity 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0004461 lactose synthase activity 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0000822 inositol hexakisphosphate binding 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0031997 N-terminal myristoylation domain binding 0.999999999986844 -1.3156158237479e-11 3 0 0 1680 17224 GO:0003684 damaged DNA binding 0.999999999986868 -1.31318873010539e-11 68 0 0 1680 17224 GO:0015125 bile acid transmembrane transporter activity 0.999999999988301 -1.16991099863362e-11 18 0 0 1680 17224 GO:0008301 DNA binding, bending 0.999999999988301 -1.16991099863362e-11 18 0 0 1680 17224 GO:0034979 NAD-dependent protein deacetylase activity 0.999999999988301 -1.16991099863362e-11 18 0 0 1680 17224 GO:0047617 acyl-CoA hydrolase activity 0.999999999988301 -1.16991099863362e-11 18 0 0 1680 17224 GO:0004745 retinol dehydrogenase activity 0.999999999988301 -1.16991099863362e-11 18 0 0 1680 17224 GO:0010485 H4 histone acetyltransferase activity 0.999999999988301 -1.16991099863362e-11 18 0 0 1680 17224 GO:0008308 voltage-gated anion channel activity 0.999999999988301 -1.16991099863362e-11 18 0 0 1680 17224 GO:0004003 ATP-dependent DNA helicase activity 0.999999999988388 -1.16118456571689e-11 35 0 0 1680 17224 GO:0003951 NAD+ kinase activity 0.999999999990136 -9.86351096584772e-12 17 0 0 1680 17224 GO:0015215 nucleotide transmembrane transporter activity 0.999999999990136 -9.86351096584772e-12 17 0 0 1680 17224 GO:0042800 histone methyltransferase activity (H3-K4 specific) 0.999999999990136 -9.86351096584772e-12 17 0 0 1680 17224 GO:0030280 structural constituent of epidermis 0.999999999990136 -9.86351096584772e-12 17 0 0 1680 17224 GO:0005132 type I interferon receptor binding 0.999999999990136 -9.86351096584772e-12 17 0 0 1680 17224 GO:0008484 sulfuric ester hydrolase activity 0.999999999990136 -9.86351096584772e-12 17 0 0 1680 17224 GO:0008320 protein transmembrane transporter activity 0.999999999990136 -9.86351096584772e-12 17 0 0 1680 17224 GO:0070182 DNA polymerase binding 0.999999999990136 -9.86351096584772e-12 17 0 0 1680 17224 GO:0004022 alcohol dehydrogenase (NAD) activity 0.999999999990353 -9.64647841779477e-12 9 0 0 1680 17224 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go 0.999999999990353 -9.64647841779477e-12 9 0 0 1680 17224 GO:0016679 oxidoreductase activity, acting on diphenols and related substances as donors 0.999999999990353 -9.64647841779477e-12 9 0 0 1680 17224 GO:0001094 TFIID-class transcription factor binding 0.999999999990353 -9.64647841779477e-12 9 0 0 1680 17224 GO:0035014 phosphatidylinositol 3-kinase regulator activity 0.999999999990353 -9.64647841779477e-12 9 0 0 1680 17224 GO:0008510 sodium:bicarbonate symporter activity 0.999999999990353 -9.64647841779477e-12 9 0 0 1680 17224 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor 0.999999999990353 -9.64647841779477e-12 9 0 0 1680 17224 GO:0008504 monoamine transmembrane transporter activity 0.999999999990353 -9.64647841779477e-12 9 0 0 1680 17224 GO:0043422 protein kinase B binding 0.999999999990353 -9.64647841779477e-12 9 0 0 1680 17224 GO:0035251 UDP-glucosyltransferase activity 0.999999999990353 -9.64647841779477e-12 9 0 0 1680 17224 GO:0003810 protein-glutamine gamma-glutamyltransferase activity 0.999999999990353 -9.64647841779477e-12 9 0 0 1680 17224 GO:0000340 RNA 7-methylguanosine cap binding 0.999999999990353 -9.64647841779477e-12 9 0 0 1680 17224 GO:0010851 cyclase regulator activity 0.999999999990353 -9.64647841779477e-12 9 0 0 1680 17224 GO:0097157 pre-mRNA intronic binding 0.999999999990353 -9.64647841779477e-12 9 0 0 1680 17224 GO:0052650 NADP-retinol dehydrogenase activity 0.999999999990353 -9.64647841779477e-12 9 0 0 1680 17224 GO:0005222 intracellular cAMP activated cation channel activity 0.999999999990353 -9.64647841779477e-12 9 0 0 1680 17224 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity 0.999999999990353 -9.64647841779477e-12 9 0 0 1680 17224 GO:0017162 aryl hydrocarbon receptor binding 0.999999999990353 -9.64647841779477e-12 9 0 0 1680 17224 GO:0004652 polynucleotide adenylyltransferase activity 0.999999999990353 -9.64647841779477e-12 9 0 0 1680 17224 GO:0005347 ATP transmembrane transporter activity 0.999999999990353 -9.64647841779477e-12 9 0 0 1680 17224 GO:0046790 virion binding 0.999999999990353 -9.64647841779477e-12 9 0 0 1680 17224 GO:0008199 ferric iron binding 0.999999999990353 -9.64647841779477e-12 9 0 0 1680 17224 GO:0070016 armadillo repeat domain binding 0.999999999990353 -9.64647841779477e-12 9 0 0 1680 17224 GO:0008469 histone-arginine N-methyltransferase activity 0.999999999990353 -9.64647841779477e-12 9 0 0 1680 17224 GO:0042910 xenobiotic transmembrane transporter activity 0.999999999990353 -9.64647841779477e-12 9 0 0 1680 17224 GO:0003691 double-stranded telomeric DNA binding 0.999999999990353 -9.64647841779477e-12 9 0 0 1680 17224 GO:0008527 taste receptor activity 0.999999999990993 -9.00678319345468e-12 30 0 0 1680 17224 GO:0061650 ubiquitin-like protein conjugating enzyme activity 0.999999999990993 -9.00678319345468e-12 30 0 0 1680 17224 GO:0004402 histone acetyltransferase activity 0.999999999993754 -6.2462783979904e-12 60 0 0 1680 17224 GO:0032357 oxidized purine DNA binding 0.999999999993945 -6.05535603193311e-12 10 0 0 1680 17224 GO:0050786 RAGE receptor binding 0.999999999993945 -6.05535603193311e-12 10 0 0 1680 17224 GO:0070513 death domain binding 0.999999999993945 -6.05535603193311e-12 10 0 0 1680 17224 GO:0016018 cyclosporin A binding 0.999999999993945 -6.05535603193311e-12 10 0 0 1680 17224 GO:0005436 sodium:phosphate symporter activity 0.999999999993945 -6.05535603193311e-12 10 0 0 1680 17224 GO:0046972 histone acetyltransferase activity (H4-K16 specific) 0.999999999993945 -6.05535603193311e-12 10 0 0 1680 17224 GO:0043995 histone acetyltransferase activity (H4-K5 specific) 0.999999999993945 -6.05535603193311e-12 10 0 0 1680 17224 GO:0004983 neuropeptide Y receptor activity 0.999999999993945 -6.05535603193311e-12 10 0 0 1680 17224 GO:0008174 mRNA methyltransferase activity 0.999999999993945 -6.05535603193311e-12 10 0 0 1680 17224 GO:0033691 sialic acid binding 0.999999999993945 -6.05535603193311e-12 10 0 0 1680 17224 GO:0008641 ubiquitin-like modifier activating enzyme activity 0.999999999993945 -6.05535603193311e-12 10 0 0 1680 17224 GO:0019957 C-C chemokine binding 0.999999999993945 -6.05535603193311e-12 10 0 0 1680 17224 GO:0015143 urate transmembrane transporter activity 0.999999999993945 -6.05535603193311e-12 10 0 0 1680 17224 GO:0016886 ligase activity, forming phosphoric ester bonds 0.999999999993945 -6.05535603193311e-12 10 0 0 1680 17224 GO:0015217 ADP transmembrane transporter activity 0.999999999993945 -6.05535603193311e-12 10 0 0 1680 17224 GO:1901702 salt transmembrane transporter activity 0.999999999993945 -6.05535603193311e-12 10 0 0 1680 17224 GO:0031419 cobalamin binding 0.999999999993945 -6.05535603193311e-12 10 0 0 1680 17224 GO:0043996 histone acetyltransferase activity (H4-K8 specific) 0.999999999993945 -6.05535603193311e-12 10 0 0 1680 17224 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity 0.999999999993945 -6.05535603193311e-12 10 0 0 1680 17224 GO:0098505 G-rich strand telomeric DNA binding 0.999999999993945 -6.05535603193311e-12 10 0 0 1680 17224 GO:0032395 MHC class II receptor activity 0.999999999993945 -6.05535603193311e-12 10 0 0 1680 17224 GO:0016725 oxidoreductase activity, acting on CH or CH2 groups 0.999999999993945 -6.05535603193311e-12 10 0 0 1680 17224 GO:0004576 oligosaccharyl transferase activity 0.999999999993945 -6.05535603193311e-12 10 0 0 1680 17224 GO:0016004 phospholipase activator activity 0.999999999993945 -6.05535603193311e-12 10 0 0 1680 17224 GO:0000182 rDNA binding 0.999999999993945 -6.05535603193311e-12 10 0 0 1680 17224 GO:0060229 lipase activator activity 0.999999999994033 -5.96717210074398e-12 12 0 0 1680 17224 GO:0005247 voltage-gated chloride channel activity 0.999999999994033 -5.96717210074398e-12 12 0 0 1680 17224 GO:0005338 nucleotide-sugar transmembrane transporter activity 0.999999999994033 -5.96717210074398e-12 12 0 0 1680 17224 GO:0043047 single-stranded telomeric DNA binding 0.999999999994033 -5.96717210074398e-12 12 0 0 1680 17224 GO:0000295 adenine nucleotide transmembrane transporter activity 0.999999999994033 -5.96717210074398e-12 12 0 0 1680 17224 GO:0004065 arylsulfatase activity 0.999999999994033 -5.96717210074398e-12 12 0 0 1680 17224 GO:0005346 purine ribonucleotide transmembrane transporter activity 0.999999999994033 -5.96717210074398e-12 12 0 0 1680 17224 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity 0.999999999994033 -5.96717210074398e-12 12 0 0 1680 17224 GO:0004062 aryl sulfotransferase activity 0.999999999994033 -5.96717210074398e-12 12 0 0 1680 17224 GO:0016274 protein-arginine N-methyltransferase activity 0.999999999994033 -5.96717210074398e-12 12 0 0 1680 17224 GO:0016273 arginine N-methyltransferase activity 0.999999999994033 -5.96717210074398e-12 12 0 0 1680 17224 GO:0016493 C-C chemokine receptor activity 0.999999999994033 -5.96717210074398e-12 12 0 0 1680 17224 GO:0061578 Lys63-specific deubiquitinase activity 0.999999999994033 -5.96717210074398e-12 12 0 0 1680 17224 GO:0004126 cytidine deaminase activity 0.999999999994033 -5.96717210074398e-12 12 0 0 1680 17224 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity 0.999999999994033 -5.96717210074398e-12 12 0 0 1680 17224 GO:0061783 peptidoglycan muralytic activity 0.999999999994067 -5.93287164629853e-12 19 0 0 1680 17224 GO:0008061 chitin binding 0.999999999997232 -2.76843872644963e-12 8 0 0 1680 17224 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity 0.999999999997232 -2.76843872644963e-12 8 0 0 1680 17224 GO:0005049 nuclear export signal receptor activity 0.999999999997232 -2.76843872644963e-12 8 0 0 1680 17224 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses 0.999999999997232 -2.76843872644963e-12 8 0 0 1680 17224 GO:0038036 sphingosine-1-phosphate receptor activity 0.999999999997232 -2.76843872644963e-12 8 0 0 1680 17224 GO:0003993 acid phosphatase activity 0.999999999997232 -2.76843872644963e-12 8 0 0 1680 17224 GO:0030306 ADP-ribosylation factor binding 0.999999999997232 -2.76843872644963e-12 8 0 0 1680 17224 GO:0004465 lipoprotein lipase activity 0.999999999997232 -2.76843872644963e-12 8 0 0 1680 17224 GO:0005047 signal recognition particle binding 0.999999999997232 -2.76843872644963e-12 8 0 0 1680 17224 GO:0102991 myristoyl-CoA hydrolase activity 0.999999999997232 -2.76843872644963e-12 8 0 0 1680 17224 GO:0001163 RNA polymerase I regulatory region sequence-specific DNA binding 0.999999999997232 -2.76843872644963e-12 8 0 0 1680 17224 GO:0036310 annealing helicase activity 0.999999999997232 -2.76843872644963e-12 8 0 0 1680 17224 GO:0000150 recombinase activity 0.999999999997232 -2.76843872644963e-12 8 0 0 1680 17224 GO:0001013 RNA polymerase I regulatory region DNA binding 0.999999999997232 -2.76843872644963e-12 8 0 0 1680 17224 GO:0001164 RNA polymerase I CORE element sequence-specific DNA binding 0.999999999997232 -2.76843872644963e-12 8 0 0 1680 17224 GO:0030249 guanylate cyclase regulator activity 0.999999999997232 -2.76843872644963e-12 8 0 0 1680 17224 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting 0.999999999997232 -2.76843872644963e-12 8 0 0 1680 17224 GO:1990459 transferrin receptor binding 0.999999999997232 -2.76843872644963e-12 8 0 0 1680 17224 GO:0004985 opioid receptor activity 0.999999999997232 -2.76843872644963e-12 8 0 0 1680 17224 GO:0016713 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen 0.999999999997232 -2.76843872644963e-12 8 0 0 1680 17224 GO:0008035 high-density lipoprotein particle binding 0.999999999997232 -2.76843872644963e-12 8 0 0 1680 17224 GO:0051880 G-quadruplex DNA binding 0.999999999997232 -2.76843872644963e-12 8 0 0 1680 17224 GO:0032404 mismatch repair complex binding 0.999999999997232 -2.76843872644963e-12 8 0 0 1680 17224 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway 0.999999999997232 -2.76843872644963e-12 8 0 0 1680 17224 GO:0001594 trace-amine receptor activity 0.999999999997232 -2.76843872644963e-12 8 0 0 1680 17224 GO:0033170 protein-DNA loading ATPase activity 0.999999999997232 -2.76843872644963e-12 8 0 0 1680 17224 GO:0097027 ubiquitin-protein transferase activator activity 0.999999999997232 -2.76843872644963e-12 8 0 0 1680 17224 GO:0015556 C4-dicarboxylate transmembrane transporter activity 0.999999999997232 -2.76843872644963e-12 8 0 0 1680 17224 GO:0035242 protein-arginine omega-N asymmetric methyltransferase activity 0.999999999997232 -2.76843872644963e-12 8 0 0 1680 17224 GO:0035381 ATP-gated ion channel activity 0.999999999997232 -2.76843872644963e-12 8 0 0 1680 17224 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity 0.999999999997232 -2.76843872644963e-12 8 0 0 1680 17224 GO:0008420 CTD phosphatase activity 0.999999999997232 -2.76843872644963e-12 8 0 0 1680 17224 GO:0005113 patched binding 0.999999999997232 -2.76843872644963e-12 8 0 0 1680 17224 GO:0003689 DNA clamp loader activity 0.999999999997232 -2.76843872644963e-12 8 0 0 1680 17224 GO:0016885 ligase activity, forming carbon-carbon bonds 0.999999999997232 -2.76843872644963e-12 8 0 0 1680 17224 GO:0015205 nucleobase transmembrane transporter activity 0.999999999997232 -2.76843872644963e-12 8 0 0 1680 17224 GO:0050780 dopamine receptor binding 0.999999999997232 -2.76843872644963e-12 8 0 0 1680 17224 GO:0000014 single-stranded DNA endodeoxyribonuclease activity 0.999999999997232 -2.76843872644963e-12 8 0 0 1680 17224 GO:0008526 phosphatidylinositol transporter activity 0.999999999997232 -2.76843872644963e-12 8 0 0 1680 17224 GO:0043139 5'-3' DNA helicase activity 0.999999999997232 -2.76843872644963e-12 8 0 0 1680 17224 GO:1990763 arrestin family protein binding 0.999999999997232 -2.76843872644963e-12 8 0 0 1680 17224 GO:0008121 ubiquinol-cytochrome-c reductase activity 0.999999999997232 -2.76843872644963e-12 8 0 0 1680 17224 GO:0004439 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity 0.999999999997232 -2.76843872644963e-12 8 0 0 1680 17224 GO:0016681 oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor 0.999999999997232 -2.76843872644963e-12 8 0 0 1680 17224 GO:0015925 galactosidase activity 0.999999999997232 -2.76843872644963e-12 8 0 0 1680 17224 GO:0003796 lysozyme activity 0.999999999998264 -1.73564116961763e-12 15 0 0 1680 17224 GO:0042809 vitamin D receptor binding 0.999999999998264 -1.73564116961763e-12 15 0 0 1680 17224 GO:0001056 RNA polymerase III activity 0.999999999998264 -1.73564116961763e-12 15 0 0 1680 17224 GO:0035613 RNA stem-loop binding 0.999999999998264 -1.73564116961763e-12 15 0 0 1680 17224 GO:0019104 DNA N-glycosylase activity 0.999999999998264 -1.73564116961763e-12 15 0 0 1680 17224 GO:0015250 water channel activity 0.999999999998264 -1.73564116961763e-12 15 0 0 1680 17224 GO:0004659 prenyltransferase activity 0.999999999998264 -1.73564116961763e-12 15 0 0 1680 17224 GO:0003674 molecular_function 1 0 17224 1680 1 1680 17224 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ARHGAP26,THOC5,ADAL,GRIK2,RECK,MCOLN3,TUBE1,NPM1,ALG1L,CTBP2,CEBPA,BCAN,KIAA1217,SNX9,TENT5C,ABHD6,SKI,TXNDC5,IKZF5,RAP2A,TMED9,PPP2R2B,TMEM37,COG3,CPE,POU3F3,SMIM20,EIF4E3,DCC,KLHL23,EXOC6B,DSTN,LRRK2,NFIA,FEZ1,PRKAR2B,ABCC2,KCND3,FGF17,INTS6,PYCR1,ZNF788P,SLC7A1,ENPP1,WIPF3,ATP7B,MAP9,BDH2,ADRB1,BBC3,ERCC5,DIRAS1,INPP5F,CAB39L,TMOD2,TPM1,DNHD1,SCN5A,TMEM63C,ITGA6,ZNF25,TJP1,BTBD9,GPSM2,FOXG1,BBS9,HPCAL4,CHN1,FRY,PAIP2B,APLF,FLRT3,SRGAP1,TOX,CADPS2,LMAN2,ALPK1,FAM84B,DENND1C,FIGN,MOXD1,JAM2,ZNF385A,KCNQ3,SPATA6,ARID5B,EFHC2,ZNF605,FASN,FHL2,HIP1,AIG1,ST6GALNAC3,SHISA2,SNAP25,ZBBX,ARRDC4,CLN5,SPATA7,RIMKLB,GSTO2,RPL28,QPCTL,CLMN,SELENOM,LAPTM4B,HOXD13,CDH2,GVINP1,SHTN1,DOCK9,MTG1,TFCP2L1,SCAMP1,SUGCT,ABHD13,ADD2,MAPK4,GRK6,SLC19A2,PLPP1,TLR3,MAGEA3,ALDH1L1,FAM133A,RPL26L1,DNAH5,ZNF365,MYT1,SNX10,KIAA1549,KCNB2,FZD1,MYLK3,COL6A2,GAPDH,NECAB1,LRRC75A-AS1,EBPL,PFKFB2,ADM2,ADCY1,PCNX2,WNT11,DSP,ASPH,ZNF618,MAGI3,GABARAPL1,GJC1,SLC39A14,ENTPD1,CXCL10,ARHGAP21,PDLIM3,WFS1,APELA,LAMB1,RAB30,CGB2,CCDC148,GCAT,FZD8,ESRP1,CD276,BACE1,PLAG1,BIK,UBAC2,PSD3,CBS,SLC12A6,GAS6,EPHB1,ZNF219,BEX2,HMGCS1,PCBP4,GHR,ZFP36L2,MED12L,PARP9,PDLIM7,TRPM4,B9D1,MN1,VEGFC,OPLAH,RAB6B,AK4,RASA3,ATP11A,NSD1,RPL12,PCDHB7,PLOD2,SRD5A3,NEK11,PIP5KL1,BMP4,CMPK2,ATP2B4,CRISPLD1,PHC1,TLL2,CCDC126,PHACTR3,CACNG3,FGF13,TRIM16,LMCD1,NDRG2,MGAT5B,ITPR2,FAM13A,PLS3,RND2,RUFY4,CPNE2,RPS6KA2,CPVL,AADAT,TMEM86A,ITGB3,TMEM143,MPPED2,JAKMIP2,ENO1,RAPGEF5,PGBD5,ZNF391,DBN1,MARK1,KCNIP3,ATF4,PNRC1,COL4A3,ANK2,ATOX1,NFE2L1,CR2,SESN1,CRYBG3,SPNS1,DYRK1B,TRIM9,TCF7L1,KCNMB4,INSIG1,KLF12,ERN1,AHNAK2,CIART,ADGRA3,NEUROG2,TC2N,ADGRL2,CACUL1,HS6ST3,RRAGD,LONRF1,TYRO3,KCNV1,RUNX2,LGALS3,STXBP5L,HID1,SORBS3,ZNF215,ZIC2,PFN2,DOK5,SPIRE1,FHOD3,RNF180,NUMBL,GALNT1,ZBTB38,ZNF440,FRAS1,SMTN,HS3ST5,GAN,LRP6,ADCY6,MED7,FAR2,NIPAL2,VGLL4,CKAP4,NDUFA4L2,DPYSL5,B3GLCT,BTNL9,MGAT4B,EFNA3,GPSM1,STRADB,MAFB,OBSCN,SDK1,KHDRBS2,GPR19,BAIAP2,NEGR1,TBC1D2,GRIK4,KCNK15,SLC2A6,FBRSL1,PLD1,SEMA3A,RNF122,SMCO4,ID1,DOCK1,NTRK3,KIF21B,DENND3,TNKS1BP1,RADIL,PPP1R9A,SEMA6A,DDX60L,ZNF362,IDI1,TACC2,BCL6,EEPD1,ZDHHC23,MYH15,SNAI2,TMEM56,IGFBP3,RPS13,HRASLS,INTU,CSN2,LRRC8B,TDRD3,PRDM13,ACO1,RNF125,CHRNA6,VIM,IFT81,PTPRJ,RNF217,PTPRS,MAOA,HGF,MBOAT2,CTNND2,RETREG1,ARFGEF3,HEY1,TENM1,DYRK3,SLC6A9,NECAB2,KIZ,BMPR2,KLHL13,PAK5,MCTP2,RASD1,PRDM8,USP30,SLC35F1,TTC1,FOXP2,KCNMB3,TFAP2A,GTF2F2,TSC22D1,SGK1,TSPAN13,KIAA0408,SYK,ATP2B1,PCSK6,CES3,DUSP1,FOXN3,CRIP2,FERMT2,PRICKLE1,PALLD,EXOG,MGMT,SMPDL3B,HOMER3,DKK1,EBF1,DDAH1,CD37,DOCK7,FBN1,SH3BGRL2,SLC1A5,PTGES,KIF1B,PKIA,CACNA2D1,ZNF235,PLBD2,LGR4,LDLR,VAMP8,PRKCA,SLC9A7,HECTD2,TRPS1,TYMP,ZFYVE28,PALD1,SERINC2,NDUFB8,KCNS3,GLDC,GDAP1,ERGIC1,ACVR1C,SLC9C1,WISP3,KLHL3,BNIP3L,EFHC1,ZDHHC14,GNAI1,SPATA9,SH3RF1,ENPP6,BMP1,MAPK13,MFSD4A,DSEL,SERPINI1,SPRY4,NRP1,SPOCK3,SEMA6B,KLF8,MRC2,FAM124A,TBC1D1,MLF1,ST6GAL1,DHCR24,MRPL22,HERC6,APBA1,TNFRSF19,GAS1,MTUS1,IL17D,ABLIM1,SLC7A11,RALGPS2,ADCK1,NOVA2,MYC,C1QL4,CRYBG1,SCARF2,PRKG1,SREBF1,GRIP1,CPXM2,MAST4,FAM155A,PRR16,COL9A2,GPR161,BOD1,PTCH2,DISC1,RPL26,SLC36A1,VLDLR,RAPGEF4,DCHS1,PACSIN3,NSD2,PEX5L,NPC2,CDC42BPA,TMEM74,MMP15,PLEKHH2,PELI2,THBS4,C1orf21,LRRIQ3,MATN2,WDR19,MPP2,DYNC2LI1,SQLE,SFMBT1,DHCR7,SLFN5,SMYD3,NBL1,TCTN2,ST14,RHOD,CCDC110,MSR1,PLXNA2,TMEM170B,DDR1,COL14A1,ZFYVE9,TIAM2,CCDC120,SPEG,ERG28,ASNS,ZNF438,POU5F1B,ALDOC,SHF,PDE4D,GATM,GAB2,TRDMT1,B3GALT1,CYB5R2,SHANK2,PANK1,PREX1,NLGN4X,SATB2,CBY1,ATF3,ATP1B1,ATOH1,PYGO1,ATP10D,C9orf116,SNCA,ISG20,PATJ,ZNF711,IKZF3,POPDC3,BEX3,TDO2,CCNA1,ZNF704,HPGD,BMPR1A,COBL,MID1,STON2,PURG,HACE1,MYO1D,PLSCR4,IGFBP6,EPS8,HERC5,KIF5C,NDFIP2,TPD52L1,INPP1,ADGRB2,GSAP,ATXN7L1,RASSF8,LRRC55,IRX5,AFF2,GPR155,RMDN2,DYNC2H1,CERS4,ERRFI1,TBC1D9,SMAD6,B4GALT6,SLC40A1,VAV3,ALDH2,ARHGEF28,SH3BP2,PXN,GSTM2,AGPAT4,PTPN13,TMEM126A,RPL21,ZDHHC15,UCHL3,HOXA1,ZFP62,TERT,PLXDC2,MCC,SVIL,LRRK1,CERS1,TNFRSF17,DDIT3,LARP1,ACSL1,UGT8,PTPN21,ACTL8,C20orf194,SLC2A13,HMCN1,CHST10,F3,GSDME,ADPRHL1,EPCAM,SIPA1L2,PPM1E,ABI3BP,TRPC1,CNNM2,CTTN,MYRIP,IL1RAP,PDGFRB,CYP1B1,TNK2,SESN2,SKAP2,CEMIP2,JPH1,YAP1,COTL1,TMEM47,SGK2,GSN,GPRC5B,HPSE,FAM114A2,OXTR,TNFSF4,PPARGC1A,MAGI2,FRMD5,PCSK5,GPR63,GPT2,SV2B,MOCOS,ZNF395,OTOGL,RHOBTB1,SCART1,BVES,STXBP6,FBXO4,CHADL,SCD,CHSY1,SPINK5,PCDHB14,FAM27E3,RNF141,ZNF354A,EEF2,SLC30A4,INAVA,LIMCH1,VSIR,RNF148,CEBPD,CAND2,SNX7,ZNF629,CDH26,PCDH10,ATP5IF1,HBG2,PODXL2,RHOQ,GSTM4,SDC3,SLC46A3,STEAP1,HERPUD1,RIPOR2,PLAGL1,NCR3LG1,FAT1,SH3BP4,RAB31,TMEM117,NXPH4,PTPRN2,DISP2,NKX2-8,FNBP1L,OSBPL6,DMXL2,SORBS1,PSTPIP2,ARHGAP22,HECW2,COL18A1,COBLL1,CANX,PIBF1,SCIN,CD53,PDZD8,CDC14B,ERO1B,PPFIBP1,KAZN,FABP6,REEP1,ACVR2A,FHIT,PROS1,TMEM120B,NTNG1,SP140L,ALG10B,ANTXR2,PRAME,PTPRU,PTPN6,MVD,C3orf52,TCEAL3,EFCC1,AMIGO1,CD40,CENPV,BATF3,ZNF569,BCL11A,CAMK2N1,MAGEA12,ZNF93,KPNA3,TRIM34,RBPMS2,TMPRSS9,EIF4EBP1,RGS10,DUSP19,RNF130,MAST1,ENO2,TSPAN15,ARHGEF11,ARL15,CMTM8,TNFSF13B,SSX1,IGF2BP2,COL4A5,FAM117B,SLX1B,OVOL2,BMP6,MCU,SYDE2,FSD1,RAB11FIP5,KCNJ4,SCN1B,PRKCD,STC2,ACTA2,MARCH3,AFAP1L2,IPCEF1,TESPA1,RBMS2,PNMA2,CARD6,USP2,KDM5B,HNF4G,CRIM1,SYBU,CCDC184,ASAP3,PEAK1,GALNT14,TLR6,NAALADL2,LRAT,LEPR,CTIF,DPY19L2,SUGT1,ICA1,EDA,MFSD9,RND3,ACER2,CTSV,SLC18B1,UACA,RPS12,RNF157,IL9R,NPHP1,NATD1,ABCG1,DOC2A,GXYLT2,PDE1B,FLVCR2,AASS,PRSS12,LSM11,DNAJC3,STAT5B,CADM2,CHAC1,DOCK3,NHP2,CA8,EYA4,NOS1AP,EPDR1,PCDH7,BAG3,CDR2L,FBXO32,PPP1R26,TGFBR3,PMAIP1,DNAH6,FAAH2,PPFIA2,RAB26,KLHL29,TSHR,GGACT,ZBED9,NKX2-1,MEIS2,SMAD9,WLS,GJB2,CAP2,TGFA,ELMOD1,HACD1,MSRB3,F12,CA13,ZNF266,ALDOA,ARHGAP28,ZBTB20,TMEFF2,LPP,MEF2C,CRYL1,CARS,LATS2,GNG12,STOX2,SLK,CYP2J2,SLC36A4,TTC30B,GRPEL2,SYCP2,RSL24D1,BNIP1,BACE2,CACNB2,ZIC5,PRELID2,ST8SIA1,LOXL4,NCAM1,TSPAN9,STXBP1,GLIS1,AGL,ZNF518B,FMNL2,GFRA1,LRP12,CHRM3,RPS23,HMGCR,FADS1,BDNF,ENAM,SLC37A1,PNP,MYO10,MGST3,STAT4,RYR2,CALCRL,SMARCD3,PLS1,C1R,OR11H4,TAF4B,MBNL2,CPEB1,DHX32,BEX4,TMCO3,SH3GL2,ADAMTS3,EMILIN2,INHBE,CDH17,FBXO27,TRPC3,CSRP2,NUDT10,BTC,ZNF516,DNM3,TMSB15A,GALNT12,FAM131C,C4A,GALNT6,MYO1B,BEGAIN,RGS20,PKP2,IL13RA1,COLEC10,NRXN1,LCP2,TXNRD3,CDS1,GPR15,EPB41L3,RNF150,CHRNA5,KMO,EEF1AKMT2,COL25A1,CNKSR3,DACT1,RTKN2,PJA1,FAM155B,ARL4D,SYNGR3,JAKMIP3,RAB27B,DOCK8,SCN3A,DZANK1,SSH3,GARS,RNF145,FZD4,NPM3,KCNH5,NKX3-2,PXYLP1,RAB38,TTC28,METAP1D,FGFR1,IRS2,IQCH,GYPC,ZNF697,PEMT,GPR160,WWTR1,INPP4B,PLEKHG1,PAM,P4HA1,ALG11,RCN3,TNFSF15,DBP,PLD5,KLHL31,HOXB9,C2orf88,SERINC5,FARP1,TMEM132C,C1QTNF3,EDA2R,ROBO2,IPO5,CREB5,P2RY1,PKN1,KCNC4,TSPAN17,COL27A1,NEO1,MCF2L,BHLHA15,GAS2L3,MORN2,MYO6,NPTXR,FES,ULBP1,BCL7A,LCA5,CLYBL,MCF2L2,RAPGEF2,ELOVL3,GAREM1,RACK1,SNTB1,HEG1,PTPRC,GALNT3,ID3,TRIB3,PLPPR2,GNAO1,AKT3,XBP1,OSBPL5,SLCO5A1,HK1,SHOX2,DOCK6,DCBLD1,BTRC,FOXA1,TPT1,NMNAT3,TRIM2,SYT12,ASS1,HDGFL3,LILRB1,SYT14,NUP62CL,NOVA1,FSTL5,FKBP9,EOMES,KCNN2,KCNAB1,TCAF2,HPS1,MARVELD2,COL19A1,LIN7A,TLN2,TLR4,ETV1,NEB,ITGB7,SLC3A2,GCNT2,CD55,ABCC4,GDPD1,PLPP2,PLEKHA1,BATF,TCERG1L,NT5DC2,PLEKHB1,TSKU,RUSC1-AS1,INHBC,MAP2,P4HA2,GNB4,TECPR2,TIGD4,TNFRSF1A,PIK3C2B,DLX2,PXDC1,MLLT3,CHMP4C,PRKAA2,RGS16,CHCHD7,ITPRIP,UBASH3B,ZCCHC24,SETBP1,RASL11B,MLC1,IL18R1,PGAP1,HSPA12B,EFEMP1,KIAA1958,PRTFDC1,IGF1R,SEMA4F,ABCA5,BCHE,GATA2,PDE10A,BNIP3,SLCO4C1,FBXL2,PAK1,FGFR4,CHSY3,MID2,UNC5C,RNF170,SLC27A2,HOMER2,TCEA3,SPATA13,PPFIA4,WDR25,PDE8A,TEX9,LDHD,MAPKAPK2,ATPAF2,CSF1,MFSD2A,HEYL,PANK3,TESC,MME,SFN,SIX2,PRKN,AVPI1,CFH,AKAP5,RBFOX2,LPCAT2,XYLT1,RNF24,OR51B4,ZNF83,SLC7A2,LPIN3,KBTBD11,CBLN1,PCLO,CTNNA2,CYP26A1,TBC1D19,FAM131B,RIDA,SLC22A17,ZDHHC6,LHX6,MYO3B,ADGRL1,CLVS2,SCN2A,ZNF488,CTH,GLI1,TMEM67,EVL,TUBA1A,UROS,NOP53,THSD4,FGF12,GSTO1,RARRES2,PAGE5,FRK,ETNPPL,JAM3,C4BPB,SMAD3,RANBP2,NRG3,PTK7,GBP1,ITGA2,ABI3,KCNG1,SEPT5,TTC39A,ZNF701,C8orf48,CNTN1,MAN2B2,PCDH18,COL9A3,LPAR2,IL32,GRB14,RUSC2,APBB1,NLRP14,BLVRB,GABRG2,SELL,HBE1,SFXN3,ARHGAP44,PPP2R3A,TECPR1,MAP1A,FUT9,EIF1,RASD2,PRICKLE2,SH3PXD2B,KLF9,PCK2,ESD,SLC45A3,DLGAP1,MOB1B,PPP1R3D,MICAL2,NUGGC,LITAF,NUAK2,TGDS,FNDC3A,NPDC1,MKX,MAP10,TMEM237,FAT4,L3MBTL4,ZNF214,FMO4,ZNF808,ZNF474,DLG2,RPL4,SLC22A15,PAX9,MYRF,THAP10,TBC1D4,MYCBP2,CGN,ACVR1,PAGE1,PPP4R4,LANCL3,DUSP8,SIDT1,ATP8A1,PPFIBP2,GATA3,ENAH,ADAMTS6,AARS,DACH2,RAC3,NCS1,STK24,MOK,CFHR1,FAM168A,SLC22A18,SLC16A2,GSTM3,ATRNL1,SP140,MAGEA6,PACSIN1,RCAN3,PLTP,TBC1D8,EML6,DCDC1,NR6A1,KLHL4,ALDH1L2,DNAJC6,DEPTOR,DESI1,MEF2B,AGO4,SLC25A28,TNS1,ACVR2B,SAV1,ARHGEF26,GPC6,GPR150,AHRR,SFXN1,HLF,NCKAP1L,PLK2,CCDC181,ENTPD7,RASGRF2,CCBE1,B3GALT2,SEMA3C,UNC5B,SPART,ZBED8,LZTS1,EFNB2,INPPL1,CELSR1,EHHADH,ALOX5AP,PTPRD,ZHX3,SCN8A,GABRB2,OLAH,SLC25A27,OPHN1,GTF2IRD1,ISYNA1,TNFRSF10C,SLC1A3,ADSSL1,DYNC1I1,CHD5,RPL13A,PRRG4,MYORG,MECOM,MCOLN2,GBGT1,PDZD7,PIK3AP1,MSMO1,RUNDC3B,OPN3,PRELID1,SLC16A9,MPDZ,TSPAN12,RIMS2,RNF152,IGSF3,EPB41L5,QSOX1,TBC1D8B,PLEKHA8,COL4A4,TCF24,TTC30A,TTYH2,COLGALT2,RABAC1,PLCB1,C4orf19,ZNF558,FAM162A,DAGLA,PMEPA1,PKN3,IQSEC2,AMPD1,ACSM3,EPHA3,PLA2G4A,TBKBP1,AMOTL1,PCSK1N,ELOVL4,RASAL2,RNF144A,GPR65,ZNF311,OTX1,CHUK,KCTD12,SPATS2L,NUDT12,TBC1D30,NELL2,ZNF827,TENT5A,STARD4,SCRN1,NBEA,DAB2IP,MARCKS,SERPINH1,ATP6AP1L,VNN2,PDK1,TMEM43,SOX21,SFXN4,PRKCQ,PNMA6A,TBC1D16,DCBLD2,ZNF396,HTR7,PRKCB,ASIC1,MAP3K21,GRB10,KLF5,HS3ST3B1,ATG5,MAPK10,NR3C2,KCTD1,THOC3,DENND5B,RPS20,ANO10,WASF3,MXI1,ATP9A,CLBA1,ARL2,GABRR2,RGS7,SELENOP,GDPD5,SLC35G2,NEDD4,HOPX,KDM7A,RGS17,FTCDNL1,SOAT2,MGAT1,SGK3,PRKG2,RALGAPA2,SLC6A15,PHYKPL,FIG4,YBX3,GFI1,SEPT3,SPRY2,SMPDL3A,PFKFB4,ARAP2,SYNPO2,HYKK,CACNA1E,MPP1,CTTNBP2NL,GUCY1A2,SKAP1,ZNF714,ZIC1,GPLD1,CEBPB,FGR,OR2T33,CLDN12,PCGF2,TUFT1,PGM2L1,GRIN2D,MYOM2,OCLN,B4GALT7,SLC43A1,ATP1A3,NUDT17,MPZL3,EXPH5,MVK,KIF5A,HEBP1,UGDH,TNFAIP8L2,JCHAIN,ABAT,ABHD4,DNER,RBM11,CACNB4,IKZF2,KREMEN1,SLCO3A1,FKBP11,QPRT,RTN1,ARHGEF10L,TUBB4A,CYP51A1,LRRC6,GRHL1,AKAP7,DLX6,SLC10A7,POF1B,HRK,SLC2A12,EPHB6,PCOLCE2,PTPRE,FANK1,GALNT18,OR2W3,SLIT2,RASGRP1,PRKACB,ATL1,GPM6A,CAPN5,ZNF565,ROR1,RNF44,SERGEF,GRK3,EML1,TMEM132B,AK1,NCAM2,C8orf88,NCOA7,APBA2,SLC9B1,UST,BCL11B,FN1,SEC24D,JDP2,ELOVL7,RIMKLA,CYP4V2,YPEL2,LAMC3,ATP6V1E2,GALNT13,PHGDH,SATB1,CD7,ADGRG6,DDIT4,OTUD1,CA2,RPS11,EBF4,NCEH1,MORN4,BARX1,NOS3,GPR176,IL17RD,RAX,SH2D2A,MSTN,PARD3B,EDEM3,DUSP9,WWC1,GALNT17,LHPP,PRDM1,B4GALNT3,AMDHD1,GLCE,ADGRB3,FCHO2,HK2,RAI14,EGFL7,CREB3L2,CXCR5,EML5,NEK10,ZSWIM5,IL15,CELSR3,PLEKHA5,MORC4,BCL6B,TDRKH,LACC1,UBTD2,DOCK2,SP8,ZSCAN5A,KCTD15,SETDB2,UNC13B,RPS6KL1,ZNF521,MAP7,STEAP3,GULP1,MDH1B,WWC2,MET,POU2F2,ZNF460,HSPA2,DPP10,PHLDB2,FER,GCA,SLC39A8,TES,SYNJ2BP,TTLL7,DOCK5,C1orf174,TPK1,WARS,MSC,LMLN,BACH2,FAAP20,SOHLH2,DISP1,CYP2U1,LIFR,PSPH,OR51B5,TNIK,PRSS16,CLGN,REL,LRP4,NSUN6,CLSTN2,NOTUM,CUEDC2,RPL34,NKX6-1,CHN2,GTSF1,DSG2,EHD3,KIAA0319,TRIM3,DHRS12,IQGAP3,RRAS2,FKBP14,TNFRSF11A,RIN2,MSX1,RAB3B,NR4A1,ESRRG,CYTH3,OGDHL,GRID1,PRRG1,MARS,AGAP2,PHACTR2,CCNG1,ARHGAP32,ZFPM2,MAP1B,RERE,ADAMTS17,GPR37,TIFA,MYADM,GCSAM,MPP7,NACC2,CT55,PRCP,MAP2K6,SLC7A5,KIF21A,GEM,MMP16,MAP3K20,SLC16A10,STOM,SNPH root NA 1 0 17224 1680 1 1680 17224 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ARHGAP26,THOC5,ADAL,GRIK2,RECK,MCOLN3,TUBE1,NPM1,ALG1L,CTBP2,CEBPA,BCAN,KIAA1217,SNX9,TENT5C,ABHD6,SKI,TXNDC5,IKZF5,RAP2A,TMED9,PPP2R2B,TMEM37,COG3,CPE,POU3F3,SMIM20,EIF4E3,DCC,KLHL23,EXOC6B,DSTN,LRRK2,NFIA,FEZ1,PRKAR2B,ABCC2,KCND3,FGF17,INTS6,PYCR1,ZNF788P,SLC7A1,ENPP1,WIPF3,ATP7B,MAP9,BDH2,ADRB1,BBC3,ERCC5,INPP5F,DIRAS1,CAB39L,TMOD2,TPM1,DNHD1,SCN5A,TMEM63C,ITGA6,ZNF25,TJP1,BTBD9,GPSM2,FOXG1,BBS9,HPCAL4,CHN1,FRY,PAIP2B,APLF,FLRT3,SRGAP1,TOX,CADPS2,LMAN2,FAM84B,ALPK1,DENND1C,FIGN,MOXD1,JAM2,ZNF385A,KCNQ3,SPATA6,ARID5B,EFHC2,ZNF605,FASN,FHL2,HIP1,AIG1,ST6GALNAC3,SHISA2,SNAP25,ZBBX,ARRDC4,CLN5,SPATA7,RIMKLB,GSTO2,RPL28,QPCTL,CLMN,SELENOM,LAPTM4B,HOXD13,CDH2,GVINP1,SHTN1,DOCK9,MTG1,TFCP2L1,SCAMP1,SUGCT,ABHD13,ADD2,MAPK4,GRK6,SLC19A2,PLPP1,TLR3,MAGEA3,ALDH1L1,FAM133A,RPL26L1,ZNF365,DNAH5,MYT1,SNX10,KIAA1549,KCNB2,FZD1,MYLK3,COL6A2,GAPDH,NECAB1,LRRC75A-AS1,EBPL,PFKFB2,ADM2,ADCY1,PCNX2,WNT11,DSP,ASPH,ZNF618,MAGI3,GABARAPL1,GJC1,SLC39A14,ENTPD1,CXCL10,ARHGAP21,PDLIM3,WFS1,APELA,LAMB1,RAB30,CGB2,CCDC148,GCAT,FZD8,CD276,ESRP1,BACE1,PLAG1,BIK,UBAC2,PSD3,CBS,SLC12A6,GAS6,EPHB1,ZNF219,BEX2,HMGCS1,PCBP4,GHR,ZFP36L2,MED12L,PARP9,TRPM4,PDLIM7,B9D1,MN1,VEGFC,OPLAH,RAB6B,AK4,RASA3,ATP11A,NSD1,RPL12,PCDHB7,PLOD2,SRD5A3,NEK11,PIP5KL1,BMP4,CMPK2,ATP2B4,CRISPLD1,PHC1,TLL2,CCDC126,PHACTR3,CACNG3,FGF13,TRIM16,LMCD1,NDRG2,MGAT5B,ITPR2,FAM13A,PLS3,RND2,RUFY4,CPNE2,RPS6KA2,CPVL,AADAT,TMEM86A,ITGB3,TMEM143,MPPED2,JAKMIP2,ENO1,RAPGEF5,PGBD5,ZNF391,DBN1,MARK1,KCNIP3,ATF4,PNRC1,COL4A3,ANK2,ATOX1,NFE2L1,CR2,SESN1,CRYBG3,SPNS1,DYRK1B,TRIM9,TCF7L1,KCNMB4,INSIG1,KLF12,ERN1,AHNAK2,CIART,ADGRA3,NEUROG2,TC2N,ADGRL2,CACUL1,HS6ST3,RRAGD,LONRF1,TYRO3,KCNV1,RUNX2,LGALS3,STXBP5L,HID1,SORBS3,ZNF215,ZIC2,PFN2,DOK5,SPIRE1,FHOD3,RNF180,NUMBL,GALNT1,ZBTB38,ZNF440,FRAS1,SMTN,HS3ST5,GAN,LRP6,ADCY6,MED7,FAR2,NIPAL2,VGLL4,CKAP4,NDUFA4L2,DPYSL5,B3GLCT,BTNL9,MGAT4B,EFNA3,GPSM1,STRADB,MAFB,OBSCN,SDK1,KHDRBS2,GPR19,BAIAP2,NEGR1,TBC1D2,GRIK4,KCNK15,SLC2A6,FBRSL1,PLD1,SEMA3A,RNF122,SMCO4,ID1,DOCK1,NTRK3,KIF21B,DENND3,TNKS1BP1,RADIL,PPP1R9A,SEMA6A,DDX60L,ZNF362,IDI1,TACC2,BCL6,EEPD1,ZDHHC23,MYH15,SNAI2,TMEM56,IGFBP3,RPS13,HRASLS,INTU,CSN2,LRRC8B,TDRD3,PRDM13,ACO1,RNF125,CHRNA6,VIM,IFT81,PTPRJ,RNF217,PTPRS,MAOA,HGF,MBOAT2,CTNND2,RETREG1,ARFGEF3,HEY1,TENM1,DYRK3,SLC6A9,NECAB2,KIZ,BMPR2,KLHL13,PAK5,MCTP2,PRDM8,RASD1,USP30,SLC35F1,TTC1,FOXP2,KCNMB3,TFAP2A,GTF2F2,TSC22D1,SGK1,TSPAN13,KIAA0408,SYK,ATP2B1,CES3,PCSK6,DUSP1,FOXN3,CRIP2,PRICKLE1,FERMT2,PALLD,EXOG,MGMT,SMPDL3B,HOMER3,DKK1,EBF1,DDAH1,CD37,DOCK7,FBN1,SH3BGRL2,SLC1A5,PTGES,KIF1B,PKIA,CACNA2D1,ZNF235,PLBD2,LGR4,LDLR,VAMP8,PRKCA,SLC9A7,HECTD2,TRPS1,TYMP,ZFYVE28,PALD1,SERINC2,NDUFB8,KCNS3,GLDC,GDAP1,ERGIC1,ACVR1C,SLC9C1,WISP3,KLHL3,BNIP3L,EFHC1,ZDHHC14,GNAI1,SPATA9,SH3RF1,ENPP6,BMP1,MAPK13,MFSD4A,DSEL,SERPINI1,SPRY4,NRP1,SPOCK3,SEMA6B,KLF8,MRC2,FAM124A,TBC1D1,MLF1,ST6GAL1,DHCR24,MRPL22,HERC6,APBA1,TNFRSF19,GAS1,MTUS1,IL17D,ABLIM1,SLC7A11,RALGPS2,ADCK1,NOVA2,MYC,C1QL4,CRYBG1,SCARF2,PRKG1,SREBF1,GRIP1,CPXM2,MAST4,FAM155A,PRR16,COL9A2,GPR161,BOD1,PTCH2,DISC1,RPL26,SLC36A1,VLDLR,RAPGEF4,DCHS1,PACSIN3,NSD2,PEX5L,NPC2,CDC42BPA,TMEM74,MMP15,PLEKHH2,PELI2,THBS4,C1orf21,LRRIQ3,MATN2,WDR19,MPP2,DYNC2LI1,SQLE,SFMBT1,DHCR7,SLFN5,SMYD3,NBL1,TCTN2,ST14,RHOD,CCDC110,MSR1,PLXNA2,TMEM170B,DDR1,COL14A1,ZFYVE9,TIAM2,CCDC120,SPEG,ERG28,ASNS,ZNF438,POU5F1B,ALDOC,SHF,PDE4D,GATM,GAB2,TRDMT1,B3GALT1,CYB5R2,SHANK2,PANK1,PREX1,NLGN4X,SATB2,CBY1,ATF3,ATP1B1,ATOH1,PYGO1,ATP10D,C9orf116,SNCA,ISG20,PATJ,ZNF711,IKZF3,POPDC3,BEX3,TDO2,CCNA1,ZNF704,HPGD,BMPR1A,COBL,MID1,STON2,PURG,HACE1,MYO1D,PLSCR4,IGFBP6,EPS8,HERC5,KIF5C,NDFIP2,TPD52L1,INPP1,ADGRB2,GSAP,ATXN7L1,RASSF8,LRRC55,IRX5,AFF2,GPR155,RMDN2,DYNC2H1,CERS4,ERRFI1,TBC1D9,SMAD6,B4GALT6,SLC40A1,VAV3,ARHGEF28,ALDH2,SH3BP2,PXN,GSTM2,AGPAT4,PTPN13,TMEM126A,RPL21,ZDHHC15,UCHL3,HOXA1,ZFP62,TERT,PLXDC2,MCC,SVIL,LRRK1,TNFRSF17,CERS1,DDIT3,LARP1,ACSL1,UGT8,PTPN21,ACTL8,C20orf194,SLC2A13,HMCN1,CHST10,F3,GSDME,ADPRHL1,EPCAM,SIPA1L2,PPM1E,ABI3BP,TRPC1,CNNM2,CTTN,MYRIP,IL1RAP,PDGFRB,CYP1B1,TNK2,SESN2,SKAP2,CEMIP2,JPH1,YAP1,COTL1,TMEM47,SGK2,GSN,GPRC5B,HPSE,FAM114A2,OXTR,TNFSF4,PPARGC1A,MAGI2,FRMD5,PCSK5,GPR63,GPT2,SV2B,MOCOS,ZNF395,OTOGL,RHOBTB1,SCART1,BVES,STXBP6,FBXO4,CHADL,SCD,CHSY1,SPINK5,PCDHB14,FAM27E3,RNF141,ZNF354A,EEF2,SLC30A4,INAVA,LIMCH1,VSIR,RNF148,CEBPD,CAND2,SNX7,ZNF629,CDH26,PCDH10,ATP5IF1,HBG2,PODXL2,RHOQ,GSTM4,SDC3,SLC46A3,STEAP1,HERPUD1,RIPOR2,PLAGL1,NCR3LG1,FAT1,SH3BP4,RAB31,TMEM117,NXPH4,PTPRN2,DISP2,NKX2-8,FNBP1L,OSBPL6,DMXL2,SORBS1,PSTPIP2,ARHGAP22,HECW2,COL18A1,COBLL1,CANX,PIBF1,SCIN,CD53,PDZD8,CDC14B,ERO1B,PPFIBP1,KAZN,FABP6,REEP1,ACVR2A,FHIT,PROS1,TMEM120B,NTNG1,SP140L,ALG10B,ANTXR2,PRAME,PTPRU,PTPN6,MVD,C3orf52,TCEAL3,EFCC1,AMIGO1,CD40,CENPV,BATF3,ZNF569,BCL11A,CAMK2N1,MAGEA12,ZNF93,KPNA3,TRIM34,RBPMS2,TMPRSS9,EIF4EBP1,RGS10,DUSP19,RNF130,MAST1,ENO2,TSPAN15,ARHGEF11,ARL15,CMTM8,SSX1,TNFSF13B,IGF2BP2,COL4A5,FAM117B,SLX1B,OVOL2,BMP6,MCU,SYDE2,FSD1,RAB11FIP5,KCNJ4,SCN1B,PRKCD,STC2,ACTA2,MARCH3,AFAP1L2,IPCEF1,TESPA1,RBMS2,PNMA2,CARD6,USP2,KDM5B,HNF4G,CRIM1,SYBU,CCDC184,ASAP3,PEAK1,GALNT14,TLR6,NAALADL2,LRAT,LEPR,CTIF,DPY19L2,SUGT1,ICA1,MFSD9,EDA,RND3,ACER2,CTSV,SLC18B1,UACA,RPS12,RNF157,IL9R,NPHP1,NATD1,ABCG1,DOC2A,GXYLT2,PDE1B,FLVCR2,AASS,PRSS12,LSM11,DNAJC3,STAT5B,CADM2,CHAC1,DOCK3,NHP2,CA8,EYA4,NOS1AP,EPDR1,PCDH7,BAG3,CDR2L,FBXO32,PPP1R26,TGFBR3,PMAIP1,DNAH6,FAAH2,PPFIA2,RAB26,KLHL29,TSHR,GGACT,ZBED9,NKX2-1,MEIS2,SMAD9,WLS,GJB2,CAP2,TGFA,ELMOD1,HACD1,MSRB3,F12,CA13,ZNF266,ALDOA,ARHGAP28,ZBTB20,TMEFF2,LPP,MEF2C,CRYL1,CARS,LATS2,GNG12,STOX2,SLK,CYP2J2,SLC36A4,TTC30B,GRPEL2,SYCP2,RSL24D1,BNIP1,BACE2,CACNB2,ZIC5,PRELID2,ST8SIA1,LOXL4,NCAM1,TSPAN9,STXBP1,GLIS1,AGL,ZNF518B,FMNL2,GFRA1,LRP12,CHRM3,RPS23,HMGCR,FADS1,BDNF,ENAM,SLC37A1,PNP,MYO10,MGST3,STAT4,RYR2,CALCRL,SMARCD3,PLS1,C1R,OR11H4,TAF4B,MBNL2,CPEB1,DHX32,BEX4,TMCO3,SH3GL2,ADAMTS3,EMILIN2,INHBE,CDH17,FBXO27,TRPC3,CSRP2,NUDT10,BTC,ZNF516,DNM3,TMSB15A,GALNT12,FAM131C,C4A,GALNT6,MYO1B,BEGAIN,RGS20,PKP2,IL13RA1,COLEC10,NRXN1,LCP2,TXNRD3,CDS1,GPR15,EPB41L3,RNF150,CHRNA5,KMO,EEF1AKMT2,CNKSR3,COL25A1,DACT1,RTKN2,PJA1,FAM155B,ARL4D,SYNGR3,JAKMIP3,RAB27B,DOCK8,SCN3A,DZANK1,SSH3,GARS,RNF145,FZD4,NPM3,KCNH5,NKX3-2,PXYLP1,RAB38,TTC28,METAP1D,FGFR1,IRS2,IQCH,GYPC,ZNF697,PEMT,GPR160,WWTR1,INPP4B,PLEKHG1,PAM,P4HA1,ALG11,RCN3,TNFSF15,DBP,PLD5,KLHL31,HOXB9,C2orf88,SERINC5,FARP1,TMEM132C,C1QTNF3,EDA2R,ROBO2,IPO5,CREB5,P2RY1,PKN1,KCNC4,TSPAN17,COL27A1,NEO1,MCF2L,BHLHA15,GAS2L3,MORN2,MYO6,NPTXR,FES,ULBP1,BCL7A,LCA5,CLYBL,MCF2L2,RAPGEF2,ELOVL3,GAREM1,RACK1,SNTB1,HEG1,PTPRC,GALNT3,ID3,TRIB3,PLPPR2,GNAO1,AKT3,XBP1,OSBPL5,SLCO5A1,HK1,SHOX2,DOCK6,DCBLD1,BTRC,FOXA1,TPT1,NMNAT3,TRIM2,SYT12,ASS1,HDGFL3,LILRB1,SYT14,NUP62CL,NOVA1,FSTL5,FKBP9,EOMES,KCNN2,KCNAB1,TCAF2,HPS1,MARVELD2,COL19A1,LIN7A,TLN2,TLR4,ETV1,NEB,ITGB7,SLC3A2,GCNT2,CD55,ABCC4,GDPD1,PLPP2,PLEKHA1,BATF,TCERG1L,NT5DC2,PLEKHB1,TSKU,RUSC1-AS1,INHBC,MAP2,P4HA2,GNB4,TECPR2,TIGD4,TNFRSF1A,PIK3C2B,DLX2,PXDC1,MLLT3,CHMP4C,PRKAA2,RGS16,CHCHD7,ITPRIP,UBASH3B,ZCCHC24,SETBP1,RASL11B,MLC1,IL18R1,PGAP1,HSPA12B,EFEMP1,KIAA1958,PRTFDC1,IGF1R,SEMA4F,ABCA5,BCHE,GATA2,PDE10A,BNIP3,SLCO4C1,FBXL2,PAK1,FGFR4,CHSY3,MID2,UNC5C,RNF170,SLC27A2,HOMER2,TCEA3,SPATA13,PPFIA4,WDR25,PDE8A,TEX9,LDHD,MAPKAPK2,ATPAF2,CSF1,MFSD2A,HEYL,PANK3,TESC,MME,SFN,SIX2,PRKN,AVPI1,CFH,AKAP5,RBFOX2,LPCAT2,XYLT1,RNF24,OR51B4,ZNF83,SLC7A2,LPIN3,KBTBD11,CBLN1,PCLO,CTNNA2,CYP26A1,TBC1D19,FAM131B,RIDA,SLC22A17,ZDHHC6,LHX6,MYO3B,ADGRL1,CLVS2,SCN2A,ZNF488,CTH,GLI1,TMEM67,EVL,TUBA1A,UROS,NOP53,THSD4,FGF12,GSTO1,RARRES2,PAGE5,FRK,ETNPPL,JAM3,C4BPB,SMAD3,RANBP2,NRG3,PTK7,GBP1,ITGA2,ABI3,KCNG1,SEPT5,TTC39A,ZNF701,C8orf48,CNTN1,MAN2B2,PCDH18,COL9A3,LPAR2,IL32,GRB14,RUSC2,APBB1,NLRP14,BLVRB,GABRG2,SELL,HBE1,SFXN3,PPP2R3A,ARHGAP44,TECPR1,MAP1A,FUT9,EIF1,RASD2,PRICKLE2,SH3PXD2B,KLF9,PCK2,ESD,SLC45A3,DLGAP1,MOB1B,PPP1R3D,MICAL2,NUGGC,LITAF,NUAK2,TGDS,FNDC3A,NPDC1,MKX,MAP10,TMEM237,FAT4,L3MBTL4,ZNF214,FMO4,ZNF808,ZNF474,DLG2,RPL4,SLC22A15,PAX9,MYRF,THAP10,TBC1D4,MYCBP2,CGN,ACVR1,PAGE1,PPP4R4,LANCL3,DUSP8,SIDT1,ATP8A1,PPFIBP2,GATA3,ENAH,ADAMTS6,AARS,DACH2,RAC3,STK24,NCS1,MOK,CFHR1,FAM168A,SLC22A18,SLC16A2,GSTM3,ATRNL1,SP140,MAGEA6,PACSIN1,RCAN3,PLTP,TBC1D8,EML6,DCDC1,NR6A1,KLHL4,ALDH1L2,DNAJC6,DEPTOR,DESI1,MEF2B,AGO4,SLC25A28,TNS1,ACVR2B,SAV1,ARHGEF26,GPC6,GPR150,AHRR,SFXN1,HLF,NCKAP1L,PLK2,CCDC181,ENTPD7,RASGRF2,CCBE1,B3GALT2,SEMA3C,UNC5B,SPART,ZBED8,LZTS1,EFNB2,INPPL1,CELSR1,EHHADH,ALOX5AP,PTPRD,ZHX3,SCN8A,GABRB2,OLAH,SLC25A27,OPHN1,GTF2IRD1,ISYNA1,TNFRSF10C,SLC1A3,ADSSL1,DYNC1I1,CHD5,RPL13A,PRRG4,MYORG,MECOM,MCOLN2,GBGT1,PIK3AP1,PDZD7,MSMO1,RUNDC3B,OPN3,PRELID1,SLC16A9,MPDZ,TSPAN12,RIMS2,RNF152,IGSF3,EPB41L5,QSOX1,TBC1D8B,PLEKHA8,COL4A4,TCF24,TTC30A,TTYH2,COLGALT2,RABAC1,PLCB1,C4orf19,ZNF558,FAM162A,DAGLA,PMEPA1,PKN3,IQSEC2,AMPD1,ACSM3,EPHA3,PLA2G4A,TBKBP1,AMOTL1,PCSK1N,ELOVL4,RASAL2,RNF144A,GPR65,ZNF311,OTX1,CHUK,KCTD12,SPATS2L,NUDT12,TBC1D30,NELL2,ZNF827,TENT5A,STARD4,SCRN1,NBEA,DAB2IP,MARCKS,SERPINH1,ATP6AP1L,VNN2,PDK1,TMEM43,SOX21,SFXN4,PNMA6A,PRKCQ,TBC1D16,DCBLD2,ZNF396,HTR7,PRKCB,ASIC1,MAP3K21,GRB10,KLF5,HS3ST3B1,ATG5,MAPK10,NR3C2,KCTD1,THOC3,DENND5B,RPS20,WASF3,ANO10,MXI1,ATP9A,CLBA1,ARL2,GABRR2,RGS7,SELENOP,GDPD5,SLC35G2,NEDD4,HOPX,KDM7A,RGS17,FTCDNL1,SOAT2,MGAT1,SGK3,PRKG2,RALGAPA2,SLC6A15,PHYKPL,FIG4,YBX3,GFI1,SEPT3,SPRY2,SMPDL3A,PFKFB4,ARAP2,SYNPO2,HYKK,CACNA1E,MPP1,CTTNBP2NL,GUCY1A2,SKAP1,ZNF714,ZIC1,GPLD1,CEBPB,FGR,OR2T33,CLDN12,PCGF2,TUFT1,PGM2L1,GRIN2D,MYOM2,OCLN,B4GALT7,SLC43A1,ATP1A3,NUDT17,MPZL3,EXPH5,MVK,KIF5A,HEBP1,UGDH,TNFAIP8L2,JCHAIN,ABAT,ABHD4,DNER,RBM11,CACNB4,IKZF2,KREMEN1,SLCO3A1,FKBP11,QPRT,RTN1,ARHGEF10L,TUBB4A,CYP51A1,LRRC6,GRHL1,AKAP7,DLX6,SLC10A7,POF1B,HRK,SLC2A12,EPHB6,PCOLCE2,PTPRE,FANK1,GALNT18,OR2W3,SLIT2,RASGRP1,PRKACB,ATL1,GPM6A,CAPN5,ZNF565,ROR1,RNF44,SERGEF,GRK3,EML1,TMEM132B,AK1,NCAM2,C8orf88,NCOA7,APBA2,SLC9B1,UST,BCL11B,FN1,SEC24D,JDP2,ELOVL7,RIMKLA,CYP4V2,YPEL2,LAMC3,ATP6V1E2,GALNT13,PHGDH,SATB1,CD7,ADGRG6,DDIT4,OTUD1,CA2,RPS11,EBF4,NCEH1,MORN4,BARX1,NOS3,GPR176,RAX,IL17RD,SH2D2A,MSTN,PARD3B,EDEM3,DUSP9,WWC1,GALNT17,LHPP,PRDM1,B4GALNT3,AMDHD1,GLCE,ADGRB3,FCHO2,HK2,RAI14,EGFL7,CREB3L2,CXCR5,EML5,NEK10,ZSWIM5,IL15,CELSR3,PLEKHA5,MORC4,BCL6B,TDRKH,LACC1,UBTD2,DOCK2,SP8,ZSCAN5A,KCTD15,SETDB2,UNC13B,RPS6KL1,ZNF521,MAP7,STEAP3,GULP1,MDH1B,WWC2,MET,POU2F2,ZNF460,HSPA2,DPP10,PHLDB2,FER,GCA,SLC39A8,TES,SYNJ2BP,TTLL7,DOCK5,C1orf174,TPK1,WARS,MSC,LMLN,BACH2,FAAP20,SOHLH2,DISP1,CYP2U1,LIFR,PSPH,OR51B5,TNIK,PRSS16,CLGN,REL,LRP4,NSUN6,CLSTN2,NOTUM,CUEDC2,RPL34,NKX6-1,CHN2,GTSF1,DSG2,EHD3,KIAA0319,TRIM3,DHRS12,IQGAP3,RRAS2,FKBP14,TNFRSF11A,RIN2,MSX1,RAB3B,NR4A1,ESRRG,CYTH3,OGDHL,GRID1,PRRG1,MARS,AGAP2,PHACTR2,CCNG1,ARHGAP32,ZFPM2,MAP1B,RERE,ADAMTS17,GPR37,TIFA,MYADM,GCSAM,MPP7,NACC2,CT55,PRCP,MAP2K6,SLC7A5,KIF21A,GEM,MMP16,MAP3K20,SLC16A10,SNPH,STOM GO:0016891 endoribonuclease activity, producing 5'-phosphomonoesters 1.00000000000077 7.73313218630799e-13 27 0 0 1680 17224 GO:0015101 organic cation transmembrane transporter activity 1.00000000000077 7.73313218630799e-13 27 0 0 1680 17224 GO:0033764 steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 1.00000000000077 7.73313218630799e-13 27 0 0 1680 17224 GO:0004032 alditol:NADP+ 1-oxidoreductase activity 1.00000000000251 2.50742479837917e-12 13 0 0 1680 17224 GO:1990380 Lys48-specific deubiquitinase activity 1.00000000000251 2.50742479837917e-12 13 0 0 1680 17224 GO:0001222 transcription corepressor binding 1.00000000000251 2.50742479837917e-12 13 0 0 1680 17224 GO:0016423 tRNA (guanine) methyltransferase activity 1.00000000000251 2.50742479837917e-12 13 0 0 1680 17224 GO:0015216 purine nucleotide transmembrane transporter activity 1.00000000000251 2.50742479837917e-12 13 0 0 1680 17224 GO:0032183 SUMO binding 1.00000000000251 2.50742479837917e-12 13 0 0 1680 17224 GO:0004952 dopamine neurotransmitter receptor activity 1.00000000000251 2.50742479837917e-12 13 0 0 1680 17224 GO:0009982 pseudouridine synthase activity 1.00000000000251 2.50742479837917e-12 13 0 0 1680 17224 GO:0042954 lipoprotein transporter activity 1.00000000000251 2.50742479837917e-12 13 0 0 1680 17224 GO:0043495 protein membrane anchor 1.00000000000251 2.50742479837917e-12 13 0 0 1680 17224 GO:0043138 3'-5' DNA helicase activity 1.00000000000251 2.50742479837917e-12 13 0 0 1680 17224 GO:0097617 annealing activity 1.00000000000251 2.50742479837917e-12 13 0 0 1680 17224 GO:0004535 poly(A)-specific ribonuclease activity 1.00000000000251 2.50742479837917e-12 13 0 0 1680 17224 GO:0051010 microtubule plus-end binding 1.00000000000251 2.50742479837917e-12 13 0 0 1680 17224 GO:0043142 single-stranded DNA-dependent ATPase activity 1.00000000000251 2.50742479837917e-12 13 0 0 1680 17224 GO:0008271 secondary active sulfate transmembrane transporter activity 1.00000000000251 2.50742479837917e-12 13 0 0 1680 17224 GO:0140102 catalytic activity, acting on a rRNA 1.00000000000308 3.07556985831123e-12 21 0 0 1680 17224 GO:0004298 threonine-type endopeptidase activity 1.00000000000308 3.07556985831123e-12 21 0 0 1680 17224 GO:0008649 rRNA methyltransferase activity 1.00000000000308 3.07556985831123e-12 21 0 0 1680 17224 GO:0070003 threonine-type peptidase activity 1.00000000000308 3.07556985831123e-12 21 0 0 1680 17224 GO:0051537 2 iron, 2 sulfur cluster binding 1.00000000000308 3.07556985831123e-12 21 0 0 1680 17224 GO:0004558 alpha-1,4-glucosidase activity 1.00000000000488 4.88251548024475e-12 4 0 0 1680 17224 GO:0034191 apolipoprotein A-I receptor binding 1.00000000000488 4.88251548024475e-12 4 0 0 1680 17224 GO:0015183 L-aspartate transmembrane transporter activity 1.00000000000488 4.88251548024475e-12 4 0 0 1680 17224 GO:0004305 ethanolamine kinase activity 1.00000000000488 4.88251548024475e-12 4 0 0 1680 17224 GO:0043199 sulfate binding 1.00000000000488 4.88251548024475e-12 4 0 0 1680 17224 GO:0034186 apolipoprotein A-I binding 1.00000000000488 4.88251548024475e-12 4 0 0 1680 17224 GO:0001132 RNA polymerase II transcription factor activity, TBP-class protein binding 1.00000000000488 4.88251548024475e-12 4 0 0 1680 17224 GO:1990430 extracellular matrix protein binding 1.00000000000488 4.88251548024475e-12 4 0 0 1680 17224 GO:1905394 retromer complex binding 1.00000000000488 4.88251548024475e-12 4 0 0 1680 17224 GO:0004525 ribonuclease III activity 1.00000000000488 4.88251548024475e-12 4 0 0 1680 17224 GO:0016774 phosphotransferase activity, carboxyl group as acceptor 1.00000000000488 4.88251548024475e-12 4 0 0 1680 17224 GO:0004677 DNA-dependent protein kinase activity 1.00000000000488 4.88251548024475e-12 4 0 0 1680 17224 GO:0047961 glycine N-acyltransferase activity 1.00000000000488 4.88251548024475e-12 4 0 0 1680 17224 GO:0044020 histone methyltransferase activity (H4-R3 specific) 1.00000000000488 4.88251548024475e-12 4 0 0 1680 17224 GO:0034056 estrogen response element binding 1.00000000000488 4.88251548024475e-12 4 0 0 1680 17224 GO:0050294 steroid sulfotransferase activity 1.00000000000488 4.88251548024475e-12 4 0 0 1680 17224 GO:0031014 troponin T binding 1.00000000000488 4.88251548024475e-12 4 0 0 1680 17224 GO:0016936 galactoside binding 1.00000000000488 4.88251548024475e-12 4 0 0 1680 17224 GO:0004945 angiotensin type II receptor activity 1.00000000000488 4.88251548024475e-12 4 0 0 1680 17224 GO:0052796 exo-alpha-(2->8)-sialidase activity 1.00000000000488 4.88251548024475e-12 4 0 0 1680 17224 GO:0047115 trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity 1.00000000000488 4.88251548024475e-12 4 0 0 1680 17224 GO:0000253 3-keto sterol reductase activity 1.00000000000488 4.88251548024475e-12 4 0 0 1680 17224 GO:0003917 DNA topoisomerase type I activity 1.00000000000488 4.88251548024475e-12 4 0 0 1680 17224 GO:0004488 methylenetetrahydrofolate dehydrogenase (NADP+) activity 1.00000000000488 4.88251548024475e-12 4 0 0 1680 17224 GO:0001588 dopamine neurotransmitter receptor activity, coupled via Gs 1.00000000000488 4.88251548024475e-12 4 0 0 1680 17224 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity 1.00000000000488 4.88251548024475e-12 4 0 0 1680 17224 GO:0000995 transcription factor activity, core RNA polymerase III binding 1.00000000000488 4.88251548024475e-12 4 0 0 1680 17224 GO:0031728 CCR3 chemokine receptor binding 1.00000000000488 4.88251548024475e-12 4 0 0 1680 17224 GO:0031748 D1 dopamine receptor binding 1.00000000000488 4.88251548024475e-12 4 0 0 1680 17224 GO:0030197 extracellular matrix constituent, lubricant activity 1.00000000000488 4.88251548024475e-12 4 0 0 1680 17224 GO:0016744 transferase activity, transferring aldehyde or ketonic groups 1.00000000000488 4.88251548024475e-12 4 0 0 1680 17224 GO:0017099 very-long-chain-acyl-CoA dehydrogenase activity 1.00000000000488 4.88251548024475e-12 4 0 0 1680 17224 GO:0016899 oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor 1.00000000000488 4.88251548024475e-12 4 0 0 1680 17224 GO:0000285 1-phosphatidylinositol-3-phosphate 5-kinase activity 1.00000000000488 4.88251548024475e-12 4 0 0 1680 17224 GO:0042731 PH domain binding 1.00000000000488 4.88251548024475e-12 4 0 0 1680 17224 GO:0001595 angiotensin receptor activity 1.00000000000488 4.88251548024475e-12 4 0 0 1680 17224 GO:0052795 exo-alpha-(2->6)-sialidase activity 1.00000000000488 4.88251548024475e-12 4 0 0 1680 17224 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity 1.00000000000488 4.88251548024475e-12 4 0 0 1680 17224 GO:0045134 uridine-diphosphatase activity 1.00000000000488 4.88251548024475e-12 4 0 0 1680 17224 GO:0009019 tRNA (guanine-N1-)-methyltransferase activity 1.00000000000488 4.88251548024475e-12 4 0 0 1680 17224 GO:0061821 telomeric D-loop binding 1.00000000000488 4.88251548024475e-12 4 0 0 1680 17224 GO:0017018 myosin phosphatase activity 1.00000000000488 4.88251548024475e-12 4 0 0 1680 17224 GO:0000700 mismatch base pair DNA N-glycosylase activity 1.00000000000488 4.88251548024475e-12 4 0 0 1680 17224 GO:0070137 ubiquitin-like protein-specific endopeptidase activity 1.00000000000488 4.88251548024475e-12 4 0 0 1680 17224 GO:0000213 tRNA-intron endonuclease activity 1.00000000000488 4.88251548024475e-12 4 0 0 1680 17224 GO:0005476 carnitine:acyl carnitine antiporter activity 1.00000000000488 4.88251548024475e-12 4 0 0 1680 17224 GO:0055077 gap junction hemi-channel activity 1.00000000000488 4.88251548024475e-12 4 0 0 1680 17224 GO:0070579 methylcytosine dioxygenase activity 1.00000000000488 4.88251548024475e-12 4 0 0 1680 17224 GO:0102420 sn-1-glycerol-3-phosphate C16:0-DCA-CoA acyl transferase activity 1.00000000000488 4.88251548024475e-12 4 0 0 1680 17224 GO:0050501 hyaluronan synthase activity 1.00000000000488 4.88251548024475e-12 4 0 0 1680 17224 GO:0034875 caffeine oxidase activity 1.00000000000488 4.88251548024475e-12 4 0 0 1680 17224 GO:0015254 glycerol channel activity 1.00000000000488 4.88251548024475e-12 4 0 0 1680 17224 GO:0018685 alkane 1-monooxygenase activity 1.00000000000488 4.88251548024475e-12 4 0 0 1680 17224 GO:0003945 N-acetyllactosamine synthase activity 1.00000000000488 4.88251548024475e-12 4 0 0 1680 17224 GO:0004311 farnesyltranstransferase activity 1.00000000000488 4.88251548024475e-12 4 0 0 1680 17224 GO:0001515 opioid peptide activity 1.00000000000488 4.88251548024475e-12 4 0 0 1680 17224 GO:0008534 oxidized purine nucleobase lesion DNA N-glycosylase activity 1.00000000000488 4.88251548024475e-12 4 0 0 1680 17224 GO:0005176 ErbB-2 class receptor binding 1.00000000000488 4.88251548024475e-12 4 0 0 1680 17224 GO:0010521 telomerase inhibitor activity 1.00000000000488 4.88251548024475e-12 4 0 0 1680 17224 GO:0001032 RNA polymerase III type 3 promoter DNA binding 1.00000000000488 4.88251548024475e-12 4 0 0 1680 17224 GO:0070053 thrombospondin receptor activity 1.00000000000488 4.88251548024475e-12 4 0 0 1680 17224 GO:0047023 androsterone dehydrogenase activity 1.00000000000488 4.88251548024475e-12 4 0 0 1680 17224 GO:0035877 death effector domain binding 1.00000000000488 4.88251548024475e-12 4 0 0 1680 17224 GO:0031779 melanocortin receptor binding 1.00000000000488 4.88251548024475e-12 4 0 0 1680 17224 GO:0015142 tricarboxylic acid transmembrane transporter activity 1.00000000000488 4.88251548024475e-12 4 0 0 1680 17224 GO:0036042 long-chain fatty acyl-CoA binding 1.00000000000488 4.88251548024475e-12 4 0 0 1680 17224 GO:0008607 phosphorylase kinase regulator activity 1.00000000000488 4.88251548024475e-12 4 0 0 1680 17224 GO:0019136 deoxynucleoside kinase activity 1.00000000000488 4.88251548024475e-12 4 0 0 1680 17224 GO:0015137 citrate transmembrane transporter activity 1.00000000000488 4.88251548024475e-12 4 0 0 1680 17224 GO:0033300 dehydroascorbic acid transmembrane transporter activity 1.00000000000488 4.88251548024475e-12 4 0 0 1680 17224 GO:0050694 galactose 3-O-sulfotransferase activity 1.00000000000488 4.88251548024475e-12 4 0 0 1680 17224 GO:0015184 L-cystine transmembrane transporter activity 1.00000000000488 4.88251548024475e-12 4 0 0 1680 17224 GO:0008502 melatonin receptor activity 1.00000000000488 4.88251548024475e-12 4 0 0 1680 17224 GO:0034584 piRNA binding 1.00000000000488 4.88251548024475e-12 4 0 0 1680 17224 GO:0016426 tRNA (adenine) methyltransferase activity 1.00000000000488 4.88251548024475e-12 4 0 0 1680 17224 GO:0008948 oxaloacetate decarboxylase activity 1.00000000000488 4.88251548024475e-12 4 0 0 1680 17224 GO:0004971 AMPA glutamate receptor activity 1.00000000000488 4.88251548024475e-12 4 0 0 1680 17224 GO:0051731 polynucleotide 5'-hydroxyl-kinase activity 1.00000000000488 4.88251548024475e-12 4 0 0 1680 17224 GO:0035515 oxidative RNA demethylase activity 1.00000000000488 4.88251548024475e-12 4 0 0 1680 17224 GO:0005124 scavenger receptor binding 1.00000000000488 4.88251548024475e-12 4 0 0 1680 17224 GO:0004663 Rab geranylgeranyltransferase activity 1.00000000000488 4.88251548024475e-12 4 0 0 1680 17224 GO:0003986 acetyl-CoA hydrolase activity 1.00000000000488 4.88251548024475e-12 4 0 0 1680 17224 GO:0090554 phosphatidylcholine-translocating ATPase activity 1.00000000000488 4.88251548024475e-12 4 0 0 1680 17224 GO:0001129 RNA polymerase II transcription factor activity, TBP-class protein binding, involved in preinitiation complex assembly 1.00000000000488 4.88251548024475e-12 4 0 0 1680 17224 GO:0004470 malic enzyme activity 1.00000000000488 4.88251548024475e-12 4 0 0 1680 17224 GO:0008309 double-stranded DNA exodeoxyribonuclease activity 1.00000000000488 4.88251548024475e-12 4 0 0 1680 17224 GO:0004176 ATP-dependent peptidase activity 1.00000000000488 4.88251548024475e-12 4 0 0 1680 17224 GO:0004522 ribonuclease A activity 1.00000000000488 4.88251548024475e-12 4 0 0 1680 17224 GO:0010484 H3 histone acetyltransferase activity 1.00000000000488 4.88251548024475e-12 4 0 0 1680 17224 GO:0046978 TAP1 binding 1.00000000000488 4.88251548024475e-12 4 0 0 1680 17224 GO:0097643 amylin receptor activity 1.00000000000488 4.88251548024475e-12 4 0 0 1680 17224 GO:0005332 gamma-aminobutyric acid:sodium symporter activity 1.00000000000488 4.88251548024475e-12 4 0 0 1680 17224 GO:0071208 histone pre-mRNA DCP binding 1.00000000000488 4.88251548024475e-12 4 0 0 1680 17224 GO:0050051 leukotriene-B4 20-monooxygenase activity 1.00000000000488 4.88251548024475e-12 4 0 0 1680 17224 GO:0030375 thyroid hormone receptor coactivator activity 1.00000000000488 4.88251548024475e-12 4 0 0 1680 17224 GO:0008853 exodeoxyribonuclease III activity 1.00000000000488 4.88251548024475e-12 4 0 0 1680 17224 GO:0032554 purine deoxyribonucleotide binding 1.00000000000488 4.88251548024475e-12 4 0 0 1680 17224 GO:0036033 mediator complex binding 1.00000000000488 4.88251548024475e-12 4 0 0 1680 17224 GO:0035243 protein-arginine omega-N symmetric methyltransferase activity 1.00000000000488 4.88251548024475e-12 4 0 0 1680 17224 GO:0032795 heterotrimeric G-protein binding 1.00000000000488 4.88251548024475e-12 4 0 0 1680 17224 GO:0048030 disaccharide binding 1.00000000000488 4.88251548024475e-12 4 0 0 1680 17224 GO:0004477 methenyltetrahydrofolate cyclohydrolase activity 1.00000000000488 4.88251548024475e-12 4 0 0 1680 17224 GO:0046848 hydroxyapatite binding 1.00000000000488 4.88251548024475e-12 4 0 0 1680 17224 GO:0051425 PTB domain binding 1.00000000000488 4.88251548024475e-12 4 0 0 1680 17224 GO:0042328 heparan sulfate N-acetylglucosaminyltransferase activity 1.00000000000488 4.88251548024475e-12 4 0 0 1680 17224 GO:0008745 N-acetylmuramoyl-L-alanine amidase activity 1.00000000000488 4.88251548024475e-12 4 0 0 1680 17224 GO:0005497 androgen binding 1.00000000000488 4.88251548024475e-12 4 0 0 1680 17224 GO:0016503 pheromone receptor activity 1.00000000000488 4.88251548024475e-12 4 0 0 1680 17224 GO:0035241 protein-arginine omega-N monomethyltransferase activity 1.00000000000488 4.88251548024475e-12 4 0 0 1680 17224 GO:0032217 riboflavin transmembrane transporter activity 1.00000000000488 4.88251548024475e-12 4 0 0 1680 17224 GO:0004095 carnitine O-palmitoyltransferase activity 1.00000000000488 4.88251548024475e-12 4 0 0 1680 17224 GO:0070891 lipoteichoic acid binding 1.00000000000488 4.88251548024475e-12 4 0 0 1680 17224 GO:0016300 tRNA (uracil) methyltransferase activity 1.00000000000488 4.88251548024475e-12 4 0 0 1680 17224 GO:0016520 growth hormone-releasing hormone receptor activity 1.00000000000488 4.88251548024475e-12 4 0 0 1680 17224 GO:0031781 type 3 melanocortin receptor binding 1.00000000000488 4.88251548024475e-12 4 0 0 1680 17224 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity 1.00000000000488 4.88251548024475e-12 4 0 0 1680 17224 GO:0032296 double-stranded RNA-specific ribonuclease activity 1.00000000000488 4.88251548024475e-12 4 0 0 1680 17224 GO:0031544 peptidyl-proline 3-dioxygenase activity 1.00000000000488 4.88251548024475e-12 4 0 0 1680 17224 GO:0052794 exo-alpha-(2->3)-sialidase activity 1.00000000000488 4.88251548024475e-12 4 0 0 1680 17224 GO:0043125 ErbB-3 class receptor binding 1.00000000000488 4.88251548024475e-12 4 0 0 1680 17224 GO:0070404 NADH binding 1.00000000000488 4.88251548024475e-12 4 0 0 1680 17224 GO:0043734 DNA-N1-methyladenine dioxygenase activity 1.00000000000488 4.88251548024475e-12 4 0 0 1680 17224 GO:0086089 voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization 1.00000000000488 4.88251548024475e-12 4 0 0 1680 17224 GO:0005315 inorganic phosphate transmembrane transporter activity 1.00000000000488 4.88251548024475e-12 4 0 0 1680 17224 GO:0030943 mitochondrion targeting sequence binding 1.00000000000488 4.88251548024475e-12 4 0 0 1680 17224 GO:0004096 catalase activity 1.00000000000488 4.88251548024475e-12 4 0 0 1680 17224 GO:0033220 amide-transporting ATPase activity 1.00000000000488 4.88251548024475e-12 4 0 0 1680 17224 GO:0001851 complement component C3b binding 1.00000000000488 4.88251548024475e-12 4 0 0 1680 17224 GO:0070139 SUMO-specific endopeptidase activity 1.00000000000488 4.88251548024475e-12 4 0 0 1680 17224 GO:0035368 selenocysteine insertion sequence binding 1.00000000000488 4.88251548024475e-12 4 0 0 1680 17224 GO:0001733 galactosylceramide sulfotransferase activity 1.00000000000488 4.88251548024475e-12 4 0 0 1680 17224 GO:0034338 short-chain carboxylesterase activity 1.00000000000488 4.88251548024475e-12 4 0 0 1680 17224 GO:0004082 bisphosphoglycerate mutase activity 1.00000000000488 4.88251548024475e-12 4 0 0 1680 17224 GO:0001847 opsonin receptor activity 1.00000000000488 4.88251548024475e-12 4 0 0 1680 17224 GO:0003960 NADPH:quinone reductase activity 1.00000000000488 4.88251548024475e-12 4 0 0 1680 17224 GO:0031782 type 4 melanocortin receptor binding 1.00000000000488 4.88251548024475e-12 4 0 0 1680 17224 GO:0008332 low voltage-gated calcium channel activity 1.00000000000488 4.88251548024475e-12 4 0 0 1680 17224 GO:0016401 palmitoyl-CoA oxidase activity 1.00000000000488 4.88251548024475e-12 4 0 0 1680 17224 GO:0071253 connexin binding 1.00000000000488 4.88251548024475e-12 4 0 0 1680 17224 GO:0032137 guanine/thymine mispair binding 1.00000000000488 4.88251548024475e-12 4 0 0 1680 17224 GO:0042806 fucose binding 1.00000000000488 4.88251548024475e-12 4 0 0 1680 17224 GO:0070326 very-low-density lipoprotein particle receptor binding 1.00000000000488 4.88251548024475e-12 4 0 0 1680 17224 GO:0015440 peptide-transporting ATPase activity 1.00000000000488 4.88251548024475e-12 4 0 0 1680 17224 GO:0046538 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity 1.00000000000488 4.88251548024475e-12 4 0 0 1680 17224 GO:0004982 N-formyl peptide receptor activity 1.00000000000488 4.88251548024475e-12 4 0 0 1680 17224 GO:0047756 chondroitin 4-sulfotransferase activity 1.00000000000488 4.88251548024475e-12 4 0 0 1680 17224 GO:0017150 tRNA dihydrouridine synthase activity 1.00000000000488 4.88251548024475e-12 4 0 0 1680 17224 GO:0046977 TAP binding 1.00000000000488 4.88251548024475e-12 4 0 0 1680 17224 GO:0035594 ganglioside binding 1.00000000000488 4.88251548024475e-12 4 0 0 1680 17224 GO:0031730 CCR5 chemokine receptor binding 1.00000000000488 4.88251548024475e-12 4 0 0 1680 17224 GO:1904288 BAT3 complex binding 1.00000000000488 4.88251548024475e-12 4 0 0 1680 17224 GO:0004619 phosphoglycerate mutase activity 1.00000000000488 4.88251548024475e-12 4 0 0 1680 17224 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity 1.00000000000488 4.88251548024475e-12 4 0 0 1680 17224 GO:0033695 oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor 1.00000000000488 4.88251548024475e-12 4 0 0 1680 17224 GO:0019834 phospholipase A2 inhibitor activity 1.00000000000488 4.88251548024475e-12 4 0 0 1680 17224 GO:0048408 epidermal growth factor binding 1.00000000000488 4.88251548024475e-12 4 0 0 1680 17224 GO:0001730 2'-5'-oligoadenylate synthetase activity 1.00000000000488 4.88251548024475e-12 4 0 0 1680 17224 GO:0032138 single base insertion or deletion binding 1.00000000000488 4.88251548024475e-12 4 0 0 1680 17224 GO:0008080 N-acetyltransferase activity 1.00000000000491 4.90985711591648e-12 86 0 0 1680 17224 GO:0016208 AMP binding 1.00000000000518 5.18360831873958e-12 11 0 0 1680 17224 GO:0005221 intracellular cyclic nucleotide activated cation channel activity 1.00000000000518 5.18360831873958e-12 11 0 0 1680 17224 GO:0017070 U6 snRNA binding 1.00000000000518 5.18360831873958e-12 11 0 0 1680 17224 GO:0140161 monocarboxylate:sodium symporter activity 1.00000000000518 5.18360831873958e-12 11 0 0 1680 17224 GO:0051011 microtubule minus-end binding 1.00000000000518 5.18360831873958e-12 11 0 0 1680 17224 GO:0004865 protein serine/threonine phosphatase inhibitor activity 1.00000000000518 5.18360831873958e-12 11 0 0 1680 17224 GO:0035197 siRNA binding 1.00000000000518 5.18360831873958e-12 11 0 0 1680 17224 GO:0016175 superoxide-generating NADPH oxidase activity 1.00000000000518 5.18360831873958e-12 11 0 0 1680 17224 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity 1.00000000000518 5.18360831873958e-12 11 0 0 1680 17224 GO:0004596 peptide alpha-N-acetyltransferase activity 1.00000000000518 5.18360831873958e-12 11 0 0 1680 17224 GO:0004526 ribonuclease P activity 1.00000000000518 5.18360831873958e-12 11 0 0 1680 17224 GO:0004966 galanin receptor activity 1.00000000000518 5.18360831873958e-12 11 0 0 1680 17224 GO:0031996 thioesterase binding 1.00000000000518 5.18360831873958e-12 11 0 0 1680 17224 GO:0019864 IgG binding 1.00000000000518 5.18360831873958e-12 11 0 0 1680 17224 GO:0016290 palmitoyl-CoA hydrolase activity 1.00000000000518 5.18360831873958e-12 11 0 0 1680 17224 GO:0015651 quaternary ammonium group transmembrane transporter activity 1.00000000000518 5.18360831873958e-12 11 0 0 1680 17224 GO:0001134 transcription factor activity, transcription factor recruiting 1.00000000000518 5.18360831873958e-12 11 0 0 1680 17224 GO:0001055 RNA polymerase II activity 1.00000000000518 5.18360831873958e-12 11 0 0 1680 17224 GO:0030881 beta-2-microglobulin binding 1.00000000000518 5.18360831873958e-12 11 0 0 1680 17224 GO:0031078 histone deacetylase activity (H3-K14 specific) 1.00000000000518 5.18360831873958e-12 11 0 0 1680 17224 GO:1990825 sequence-specific mRNA binding 1.00000000000518 5.18360831873958e-12 11 0 0 1680 17224 GO:0001054 RNA polymerase I activity 1.00000000000518 5.18360831873958e-12 11 0 0 1680 17224 GO:0099602 neurotransmitter receptor regulator activity 1.00000000000518 5.18360831873958e-12 11 0 0 1680 17224 GO:0004303 estradiol 17-beta-dehydrogenase activity 1.00000000000518 5.18360831873958e-12 11 0 0 1680 17224 GO:0004143 diacylglycerol kinase activity 1.00000000000518 5.18360831873958e-12 11 0 0 1680 17224 GO:0019531 oxalate transmembrane transporter activity 1.00000000000518 5.18360831873958e-12 11 0 0 1680 17224 GO:0032356 oxidized DNA binding 1.00000000000518 5.18360831873958e-12 11 0 0 1680 17224 GO:0030548 acetylcholine receptor regulator activity 1.00000000000518 5.18360831873958e-12 11 0 0 1680 17224 GO:0032041 NAD-dependent histone deacetylase activity (H3-K14 specific) 1.00000000000518 5.18360831873958e-12 11 0 0 1680 17224 GO:0043855 cyclic nucleotide-gated ion channel activity 1.00000000000518 5.18360831873958e-12 11 0 0 1680 17224 GO:0034452 dynactin binding 1.00000000000518 5.18360831873958e-12 11 0 0 1680 17224 GO:0016289 CoA hydrolase activity 1.00000000000773 7.73045167044026e-12 20 0 0 1680 17224 GO:0070628 proteasome binding 1.00000000000773 7.73045167044026e-12 20 0 0 1680 17224 GO:0033038 bitter taste receptor activity 1.00000000000818 8.18136907414556e-12 24 0 0 1680 17224 GO:0008171 O-methyltransferase activity 1.00000000000818 8.18136907414556e-12 24 0 0 1680 17224 GO:0003678 DNA helicase activity 1.00000000000823 8.23395475807973e-12 49 0 0 1680 17224 GO:0031492 nucleosomal DNA binding 1.00000000000905 9.0497573720204e-12 45 0 0 1680 17224 GO:0036002 pre-mRNA binding 1.00000000001015 1.01451089588117e-11 36 0 0 1680 17224 GO:0061733 peptide-lysine-N-acetyltransferase activity 1.00000000001149 1.14931437127548e-11 62 0 0 1680 17224 GO:0048020 CCR chemokine receptor binding 1.0000000000145 1.44975515508971e-11 40 0 0 1680 17224 GO:0015355 secondary active monocarboxylate transmembrane transporter activity 1.00000000001662 1.66218175434818e-11 14 0 0 1680 17224 GO:0050700 CARD domain binding 1.00000000001662 1.66218175434818e-11 14 0 0 1680 17224 GO:0019206 nucleoside kinase activity 1.00000000001662 1.66218175434818e-11 14 0 0 1680 17224 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis 1.00000000001662 1.66218175434818e-11 14 0 0 1680 17224 GO:0035240 dopamine binding 1.00000000001662 1.66218175434818e-11 14 0 0 1680 17224 GO:0015116 sulfate transmembrane transporter activity 1.00000000001662 1.66218175434818e-11 14 0 0 1680 17224 GO:0044548 S100 protein binding 1.00000000001662 1.66218175434818e-11 14 0 0 1680 17224 GO:0003688 DNA replication origin binding 1.00000000001662 1.66218175434818e-11 14 0 0 1680 17224 GO:0030983 mismatched DNA binding 1.00000000001662 1.66218175434818e-11 14 0 0 1680 17224 GO:0098847 sequence-specific single stranded DNA binding 1.00000000001662 1.66218175434818e-11 14 0 0 1680 17224 GO:0003899 DNA-directed 5'-3' RNA polymerase activity 1.00000000001801 1.80106273836122e-11 41 0 0 1680 17224 GO:0008519 ammonium transmembrane transporter activity 1.00000000002317 2.3167524540256e-11 32 0 0 1680 17224 GO:0005549 odorant binding 1.00000000002386 2.38636266745885e-11 84 0 0 1680 17224 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity 1.00000000002422 2.42224713042398e-11 31 0 0 1680 17224 GO:0008106 alcohol dehydrogenase (NADP+) activity 1.00000000002524 2.52447428875303e-11 22 0 0 1680 17224 GO:0005184 neuropeptide hormone activity 1.00000000002599 2.59925907384141e-11 29 0 0 1680 17224 GO:0008094 DNA-dependent ATPase activity 1.00000000002725 2.72502630836275e-11 85 0 0 1680 17224 GO:0034212 peptide N-acetyltransferase activity 1.0000000000278 2.77980500363361e-11 70 0 0 1680 17224