TermID	Term	Enrichment	logP	Genes in Term	Target Genes in Term	Fraction of Targets in Term	Total Target Genes	Total Genes	Entrez Gene IDs	Gene Symbols
SMP00092	Rosuvastatin Action Pathway	0.000301702086709079	-8.10607049531977	21	9	0.076271186440678	118	992	1595,3157,3422,4598,6307,4597,1718,6713,3156	CYP51A1,HMGCS1,IDI1,MVK,MSMO1,MVD,DHCR24,SQLE,HMGCR
SMP00508	Cholesteryl ester storage disease	0.000301702086709079	-8.10607049531977	21	9	0.076271186440678	118	992	1595,3157,3422,4598,6307,4597,1718,6713,3156	CYP51A1,HMGCS1,IDI1,MVK,MSMO1,MVD,DHCR24,SQLE,HMGCR
SMP00510	Mevalonic aciduria	0.000301702086709079	-8.10607049531977	21	9	0.076271186440678	118	992	1595,3157,3422,4598,6307,4597,1718,6713,3156	CYP51A1,HMGCS1,IDI1,MVK,MSMO1,MVD,DHCR24,SQLE,HMGCR
SMP00387	CHILD Syndrome	0.000301702086709079	-8.10607049531977	21	9	0.076271186440678	118	992	1595,3157,3422,4598,6307,4597,1718,6713,3156	CYP51A1,HMGCS1,IDI1,MVK,MSMO1,MVD,DHCR24,SQLE,HMGCR
SMP00095	Alendronate Action Pathway	0.000301702086709079	-8.10607049531977	21	9	0.076271186440678	118	992	1595,3157,3422,4598,6307,4597,1718,6713,3156	CYP51A1,HMGCS1,IDI1,MVK,MSMO1,MVD,DHCR24,SQLE,HMGCR
SMP00107	Zoledronate Action Pathway	0.000301702086709079	-8.10607049531977	21	9	0.076271186440678	118	992	1595,3157,3422,4598,6307,4597,1718,6713,3156	CYP51A1,HMGCS1,IDI1,MVK,MSMO1,MVD,DHCR24,SQLE,HMGCR
SMP00389	Smith-Lemli-Opitz Syndrome (SLOS)	0.000301702086709079	-8.10607049531977	21	9	0.076271186440678	118	992	1595,3157,3422,4598,6307,4597,1718,6713,3156	CYP51A1,HMGCS1,IDI1,MVK,MSMO1,MVD,DHCR24,SQLE,HMGCR
SMP00112	Risedronate Action Pathway	0.000301702086709079	-8.10607049531977	21	9	0.076271186440678	118	992	1595,3157,3422,4598,6307,4597,1718,6713,3156	CYP51A1,HMGCS1,IDI1,MVK,MSMO1,MVD,DHCR24,SQLE,HMGCR
SMP00119	Fluvastatin Action Pathway	0.000301702086709079	-8.10607049531977	21	9	0.076271186440678	118	992	1595,3157,3422,4598,6307,4597,1718,6713,3156	CYP51A1,HMGCS1,IDI1,MVK,MSMO1,MVD,DHCR24,SQLE,HMGCR
SMP00079	Ibandronate Action Pathway	0.000301702086709079	-8.10607049531977	21	9	0.076271186440678	118	992	1595,3157,3422,4598,6307,4597,1718,6713,3156	CYP51A1,HMGCS1,IDI1,MVK,MSMO1,MVD,DHCR24,SQLE,HMGCR
SMP00209	Hypercholesterolemia	0.000301702086709079	-8.10607049531977	21	9	0.076271186440678	118	992	1595,3157,3422,4598,6307,4597,1718,6713,3156	CYP51A1,HMGCS1,IDI1,MVK,MSMO1,MVD,DHCR24,SQLE,HMGCR
SMP00388	Chondrodysplasia Punctata II- X Linked Dominant (CDPX2)	0.000301702086709079	-8.10607049531977	21	9	0.076271186440678	118	992	1595,3157,3422,4598,6307,4597,1718,6713,3156	CYP51A1,HMGCS1,IDI1,MVK,MSMO1,MVD,DHCR24,SQLE,HMGCR
SMP00386	Desmosterolosis	0.000301702086709079	-8.10607049531977	21	9	0.076271186440678	118	992	1595,3157,3422,4598,6307,4597,1718,6713,3156	CYP51A1,HMGCS1,IDI1,MVK,MSMO1,MVD,DHCR24,SQLE,HMGCR
SMP00511	Wolman disease	0.000301702086709079	-8.10607049531977	21	9	0.076271186440678	118	992	1595,3157,3422,4598,6307,4597,1718,6713,3156	CYP51A1,HMGCS1,IDI1,MVK,MSMO1,MVD,DHCR24,SQLE,HMGCR
SMP00023	Steroid Biosynthesis	0.000301702086709079	-8.10607049531977	21	9	0.076271186440678	118	992	1595,3157,3422,4598,6307,4597,1718,6713,3156	CYP51A1,HMGCS1,IDI1,MVK,MSMO1,MVD,DHCR24,SQLE,HMGCR
SMP00099	Lovastatin Action Pathway	0.000301702086709079	-8.10607049531977	21	9	0.076271186440678	118	992	1595,3157,3422,4598,6307,4597,1718,6713,3156	CYP51A1,HMGCS1,IDI1,MVK,MSMO1,MVD,DHCR24,SQLE,HMGCR
SMP00509	Hyper-IgD syndrome	0.000301702086709079	-8.10607049531977	21	9	0.076271186440678	118	992	1595,3157,3422,4598,6307,4597,1718,6713,3156	CYP51A1,HMGCS1,IDI1,MVK,MSMO1,MVD,DHCR24,SQLE,HMGCR
SMP00131	Atorvastatin Action Pathway	0.000301702086709079	-8.10607049531977	21	9	0.076271186440678	118	992	1595,3157,3422,4598,6307,4597,1718,6713,3156	CYP51A1,HMGCS1,IDI1,MVK,MSMO1,MVD,DHCR24,SQLE,HMGCR
SMP00082	Simvastatin Action Pathway	0.000301702086709079	-8.10607049531977	21	9	0.076271186440678	118	992	1595,3157,3422,4598,6307,4597,1718,6713,3156	CYP51A1,HMGCS1,IDI1,MVK,MSMO1,MVD,DHCR24,SQLE,HMGCR
SMP00117	Pamidronate Action Pathway	0.000301702086709079	-8.10607049531977	21	9	0.076271186440678	118	992	1595,3157,3422,4598,6307,4597,1718,6713,3156	CYP51A1,HMGCS1,IDI1,MVK,MSMO1,MVD,DHCR24,SQLE,HMGCR
SMP00319	Lysosomal Acid Lipase Deficiency (Wolman Disease)	0.000301702086709079	-8.10607049531977	21	9	0.076271186440678	118	992	1595,3157,3422,4598,6307,4597,1718,6713,3156	CYP51A1,HMGCS1,IDI1,MVK,MSMO1,MVD,DHCR24,SQLE,HMGCR
SMP00111	Cerivastatin Action Pathway	0.000301702086709079	-8.10607049531977	21	9	0.076271186440678	118	992	1595,3157,3422,4598,6307,4597,1718,6713,3156	CYP51A1,HMGCS1,IDI1,MVK,MSMO1,MVD,DHCR24,SQLE,HMGCR
SMP00089	Pravastatin Action Pathway	0.000301702086709079	-8.10607049531977	21	9	0.076271186440678	118	992	1595,3157,3422,4598,6307,4597,1718,6713,3156	CYP51A1,HMGCS1,IDI1,MVK,MSMO1,MVD,DHCR24,SQLE,HMGCR
SMP00004	Glycine and Serine Metabolism	0.000395361479505558	-7.83571007355787	26	10	0.0847457627118644	118	992	2617,217,23464,4128,875,26227,2628,5723,2731,1491	GARS,ALDH2,GCAT,MAOA,CBS,PHGDH,GATM,PSPH,GLDC,CTH
SMP00484	Dimethylglycine Dehydrogenase Deficiency	0.000395361479505558	-7.83571007355787	26	10	0.0847457627118644	118	992	2617,217,23464,4128,875,26227,2628,5723,2731,1491	GARS,ALDH2,GCAT,MAOA,CBS,PHGDH,GATM,PSPH,GLDC,CTH
SMP00244	Sarcosinemia	0.000395361479505558	-7.83571007355787	26	10	0.0847457627118644	118	992	2617,217,23464,4128,875,26227,2628,5723,2731,1491	GARS,ALDH2,GCAT,MAOA,CBS,PHGDH,GATM,PSPH,GLDC,CTH
SMP00242	Dimethylglycine Dehydrogenase Deficiency	0.000395361479505558	-7.83571007355787	26	10	0.0847457627118644	118	992	2617,217,23464,4128,875,26227,2628,5723,2731,1491	GARS,ALDH2,GCAT,MAOA,CBS,PHGDH,GATM,PSPH,GLDC,CTH
SMP00223	Non Ketotic Hyperglycinemia	0.000395361479505558	-7.83571007355787	26	10	0.0847457627118644	118	992	2617,217,23464,4128,875,26227,2628,5723,2731,1491	GARS,ALDH2,GCAT,MAOA,CBS,PHGDH,GATM,PSPH,GLDC,CTH
SMP00179	Dihydropyrimidine Dehydrogenase Deficiency (DHPD)	0.000395361479505558	-7.83571007355787	26	10	0.0847457627118644	118	992	2617,217,23464,4128,875,26227,2628,5723,2731,1491	GARS,ALDH2,GCAT,MAOA,CBS,PHGDH,GATM,PSPH,GLDC,CTH
SMP00721	3-Phosphoglycerate dehydrogenase deficiency	0.000395361479505558	-7.83571007355787	26	10	0.0847457627118644	118	992	2617,217,23464,4128,875,26227,2628,5723,2731,1491	GARS,ALDH2,GCAT,MAOA,CBS,PHGDH,GATM,PSPH,GLDC,CTH
SMP00485	Hyperglycinemia- non-ketotic	0.000395361479505558	-7.83571007355787	26	10	0.0847457627118644	118	992	2617,217,23464,875,4128,26227,2628,5723,2731,1491	GARS,ALDH2,GCAT,CBS,MAOA,PHGDH,GATM,PSPH,GLDC,CTH
SMP00455	Homocysteine Degradation	0.0140437323004007	-4.26557908235003	2	2	0.0169491525423729	118	992	875,1491	CBS,CTH
SMP00515	Homocystinuria- cystathionine beta-synthase deficiency	0.0140437323004007	-4.26557908235003	2	2	0.0169491525423729	118	992	875,1491	CBS,CTH
SMP00514	Gamma-cystathionase deficiency (CTH)	0.0140437323004007	-4.26557908235003	2	2	0.0169491525423729	118	992	875,1491	CBS,CTH
SMP00040	Glycolysis	0.0245992144472089	-3.70504076959398	15	5	0.0423728813559322	118	992	2597,2023,226,53354,3099	GAPDH,ENO1,ALDOA,PANK1,HK2
SMP00531	Glycogenosis- Type VII. Tarui disease	0.0245992144472089	-3.70504076959398	15	5	0.0423728813559322	118	992	2597,2023,226,53354,3099	GAPDH,ENO1,ALDOA,PANK1,HK2
SMP00572	Fanconi-bickel syndrome	0.0245992144472089	-3.70504076959398	15	5	0.0423728813559322	118	992	2597,2023,226,53354,3099	GAPDH,ENO1,ALDOA,PANK1,HK2
SMP00063	Tryptophan Metabolism	0.064583429358488	-2.73979741257679	19	5	0.0423728813559322	118	992	217,51166,6999,8564,7453	ALDH2,AADAT,TDO2,KMO,WARS
SMP00306	Pindolol Action Pathway	0.0647785997841195	-2.7367799804136	57	11	0.0932203389830508	118	992	3761,6331,153,6262,3752,481,7168,6641,23236,478,144245	KCNJ4,SCN5A,ADRB1,RYR2,KCND3,ATP1B1,TPM1,SNTB1,PLCB1,ATP1A3,ALG10B
SMP00323	Quinidine Action Pathway	0.0647785997841195	-2.7367799804136	57	11	0.0932203389830508	118	992	3761,6331,153,6262,481,3752,7168,6641,23236,478,144245	KCNJ4,SCN5A,ADRB1,RYR2,ATP1B1,KCND3,TPM1,SNTB1,PLCB1,ATP1A3,ALG10B
SMP00660	Sotalol Action Pathway	0.0647785997841195	-2.7367799804136	57	11	0.0932203389830508	118	992	3761,6331,153,6262,3752,481,7168,6641,23236,478,144245	KCNJ4,SCN5A,ADRB1,RYR2,KCND3,ATP1B1,TPM1,SNTB1,PLCB1,ATP1A3,ALG10B
SMP00379	Nifedipine Action Pathway	0.0647785997841195	-2.7367799804136	57	11	0.0932203389830508	118	992	3761,6331,153,6262,3752,481,7168,6641,23236,478,144245	KCNJ4,SCN5A,ADRB1,RYR2,KCND3,ATP1B1,TPM1,SNTB1,PLCB1,ATP1A3,ALG10B
SMP00325	Disopyramide Action Pathway	0.0647785997841195	-2.7367799804136	57	11	0.0932203389830508	118	992	3761,6331,153,6262,481,3752,7168,6641,23236,478,144245	KCNJ4,SCN5A,ADRB1,RYR2,ATP1B1,KCND3,TPM1,SNTB1,PLCB1,ATP1A3,ALG10B
SMP00669	Practolol Action Pathway	0.0647785997841195	-2.7367799804136	57	11	0.0932203389830508	118	992	3761,6331,153,6262,3752,481,7168,6641,23236,478,144245	KCNJ4,SCN5A,ADRB1,RYR2,KCND3,ATP1B1,TPM1,SNTB1,PLCB1,ATP1A3,ALG10B
SMP00667	Metipranolol Action Pathway	0.0647785997841195	-2.7367799804136	57	11	0.0932203389830508	118	992	3761,6331,153,6262,3752,481,7168,6641,23236,478,144245	KCNJ4,SCN5A,ADRB1,RYR2,KCND3,ATP1B1,TPM1,SNTB1,PLCB1,ATP1A3,ALG10B
SMP00380	Nimodipine Action Pathway	0.0647785997841195	-2.7367799804136	57	11	0.0932203389830508	118	992	3761,6331,153,6262,3752,481,7168,6641,23236,478,144245	KCNJ4,SCN5A,ADRB1,RYR2,KCND3,ATP1B1,TPM1,SNTB1,PLCB1,ATP1A3,ALG10B
SMP00381	Nisoldipine Action Pathway	0.0647785997841195	-2.7367799804136	57	11	0.0932203389830508	118	992	3761,6331,153,6262,3752,481,7168,6641,23236,478,144245	KCNJ4,SCN5A,ADRB1,RYR2,KCND3,ATP1B1,TPM1,SNTB1,PLCB1,ATP1A3,ALG10B
SMP00659	Timolol Action Pathway	0.0647785997841195	-2.7367799804136	57	11	0.0932203389830508	118	992	3761,6331,153,6262,3752,481,7168,6641,23236,478,144245	KCNJ4,SCN5A,ADRB1,RYR2,KCND3,ATP1B1,TPM1,SNTB1,PLCB1,ATP1A3,ALG10B
SMP00661	Epinephrine Action Pathway	0.0647785997841195	-2.7367799804136	57	11	0.0932203389830508	118	992	3761,6331,153,6262,3752,481,7168,6641,23236,478,144245	KCNJ4,SCN5A,ADRB1,RYR2,KCND3,ATP1B1,TPM1,SNTB1,PLCB1,ATP1A3,ALG10B
SMP00324	Procainamide (Antiarrhythmic) Action Pathway	0.0647785997841195	-2.7367799804136	57	11	0.0932203389830508	118	992	3761,6331,153,6262,481,3752,7168,6641,23236,478,144245	KCNJ4,SCN5A,ADRB1,RYR2,ATP1B1,KCND3,TPM1,SNTB1,PLCB1,ATP1A3,ALG10B
SMP00366	Nebivolol Action Pathway	0.0647785997841195	-2.7367799804136	57	11	0.0932203389830508	118	992	3761,6331,153,6262,3752,481,7168,6641,23236,478,144245	KCNJ4,SCN5A,ADRB1,RYR2,KCND3,ATP1B1,TPM1,SNTB1,PLCB1,ATP1A3,ALG10B
SMP00377	Felodipine Action Pathway	0.0647785997841195	-2.7367799804136	57	11	0.0932203389830508	118	992	3761,6331,153,6262,3752,481,7168,6641,23236,478,144245	KCNJ4,SCN5A,ADRB1,RYR2,KCND3,ATP1B1,TPM1,SNTB1,PLCB1,ATP1A3,ALG10B
SMP00296	Acebutolol Action Pathway	0.0647785997841195	-2.7367799804136	57	11	0.0932203389830508	118	992	3761,6331,153,6262,3752,481,7168,6641,23236,478,144245	KCNJ4,SCN5A,ADRB1,RYR2,KCND3,ATP1B1,TPM1,SNTB1,PLCB1,ATP1A3,ALG10B
SMP00305	Penbutolol Action Pathway	0.0647785997841195	-2.7367799804136	57	11	0.0932203389830508	118	992	3761,6331,153,6262,3752,481,7168,6641,23236,478,144245	KCNJ4,SCN5A,ADRB1,RYR2,KCND3,ATP1B1,TPM1,SNTB1,PLCB1,ATP1A3,ALG10B
SMP00663	Isoprenaline Action Pathway	0.0647785997841195	-2.7367799804136	57	11	0.0932203389830508	118	992	3761,6331,153,6262,3752,481,7168,6641,23236,478,144245	KCNJ4,SCN5A,ADRB1,RYR2,KCND3,ATP1B1,TPM1,SNTB1,PLCB1,ATP1A3,ALG10B
SMP00658	Carteolol Action Pathway	0.0647785997841195	-2.7367799804136	57	11	0.0932203389830508	118	992	3761,6331,153,6262,3752,481,7168,6641,23236,478,144245	KCNJ4,SCN5A,ADRB1,RYR2,KCND3,ATP1B1,TPM1,SNTB1,PLCB1,ATP1A3,ALG10B
SMP00657	Bopindolol Action Pathway	0.0647785997841195	-2.7367799804136	57	11	0.0932203389830508	118	992	3761,6331,153,6262,3752,481,7168,6641,23236,478,144245	KCNJ4,SCN5A,ADRB1,RYR2,KCND3,ATP1B1,TPM1,SNTB1,PLCB1,ATP1A3,ALG10B
SMP00664	Arbutamine Action Pathway	0.0647785997841195	-2.7367799804136	57	11	0.0932203389830508	118	992	3761,6331,153,6262,3752,481,7168,6641,23236,478,144245	KCNJ4,SCN5A,ADRB1,RYR2,KCND3,ATP1B1,TPM1,SNTB1,PLCB1,ATP1A3,ALG10B
SMP00588	Muscle/Heart Contraction	0.0647785997841195	-2.7367799804136	57	11	0.0932203389830508	118	992	3761,6331,153,6262,3752,481,7168,6641,23236,478,144245	KCNJ4,SCN5A,ADRB1,RYR2,KCND3,ATP1B1,TPM1,SNTB1,PLCB1,ATP1A3,ALG10B
SMP00298	Atenolol Action Pathway	0.0647785997841195	-2.7367799804136	57	11	0.0932203389830508	118	992	3761,6331,153,6262,3752,481,7168,6641,23236,478,144245	KCNJ4,SCN5A,ADRB1,RYR2,KCND3,ATP1B1,TPM1,SNTB1,PLCB1,ATP1A3,ALG10B
SMP00304	Oxprenolol Action Pathway	0.0647785997841195	-2.7367799804136	57	11	0.0932203389830508	118	992	3761,6331,153,6262,3752,481,7168,6641,23236,478,144245	KCNJ4,SCN5A,ADRB1,RYR2,KCND3,ATP1B1,TPM1,SNTB1,PLCB1,ATP1A3,ALG10B
SMP00332	Ibutilide Action Pathway	0.0647785997841195	-2.7367799804136	57	11	0.0932203389830508	118	992	3761,6331,153,6262,3752,481,7168,6641,23236,478,144245	KCNJ4,SCN5A,ADRB1,RYR2,KCND3,ATP1B1,TPM1,SNTB1,PLCB1,ATP1A3,ALG10B
SMP00665	Amiodarone Action Pathway	0.0647785997841195	-2.7367799804136	57	11	0.0932203389830508	118	992	3761,6331,153,6262,3752,481,7168,6641,23236,478,144245	KCNJ4,SCN5A,ADRB1,RYR2,KCND3,ATP1B1,TPM1,SNTB1,PLCB1,ATP1A3,ALG10B
SMP00378	Isradipine Action Pathway	0.0647785997841195	-2.7367799804136	57	11	0.0932203389830508	118	992	3761,6331,153,6262,3752,481,7168,6641,23236,478,144245	KCNJ4,SCN5A,ADRB1,RYR2,KCND3,ATP1B1,TPM1,SNTB1,PLCB1,ATP1A3,ALG10B
SMP00670	Bupranolol Action Pathway	0.0647785997841195	-2.7367799804136	57	11	0.0932203389830508	118	992	3761,6331,153,6262,3752,481,7168,6641,23236,478,144245	KCNJ4,SCN5A,ADRB1,RYR2,KCND3,ATP1B1,TPM1,SNTB1,PLCB1,ATP1A3,ALG10B
SMP00303	Nadolol Action Pathway	0.0647785997841195	-2.7367799804136	57	11	0.0932203389830508	118	992	3761,6331,153,6262,3752,481,7168,6641,23236,478,144245	KCNJ4,SCN5A,ADRB1,RYR2,KCND3,ATP1B1,TPM1,SNTB1,PLCB1,ATP1A3,ALG10B
SMP00297	Alprenolol Action Pathway	0.0647785997841195	-2.7367799804136	57	11	0.0932203389830508	118	992	3761,6331,153,6262,3752,481,7168,6641,23236,478,144245	KCNJ4,SCN5A,ADRB1,RYR2,KCND3,ATP1B1,TPM1,SNTB1,PLCB1,ATP1A3,ALG10B
SMP00331	Flecainide Action Pathway	0.0647785997841195	-2.7367799804136	57	11	0.0932203389830508	118	992	3761,6331,153,6262,3752,481,7168,6641,23236,478,144245	KCNJ4,SCN5A,ADRB1,RYR2,KCND3,ATP1B1,TPM1,SNTB1,PLCB1,ATP1A3,ALG10B
SMP00359	Diltiazem Action Pathway	0.0647785997841195	-2.7367799804136	57	11	0.0932203389830508	118	992	3761,6331,153,6262,3752,481,7168,6641,23236,478,144245	KCNJ4,SCN5A,ADRB1,RYR2,KCND3,ATP1B1,TPM1,SNTB1,PLCB1,ATP1A3,ALG10B
SMP00375	Verapamil Action Pathway	0.0647785997841195	-2.7367799804136	57	11	0.0932203389830508	118	992	3761,6331,153,6262,3752,481,7168,6641,23236,478,144245	KCNJ4,SCN5A,ADRB1,RYR2,KCND3,ATP1B1,TPM1,SNTB1,PLCB1,ATP1A3,ALG10B
SMP00382	Nitrendipine Action Pathway	0.0647785997841195	-2.7367799804136	57	11	0.0932203389830508	118	992	3761,6331,153,6262,3752,481,7168,6641,23236,478,144245	KCNJ4,SCN5A,ADRB1,RYR2,KCND3,ATP1B1,TPM1,SNTB1,PLCB1,ATP1A3,ALG10B
SMP00662	Dobutamine Action Pathway	0.0647785997841195	-2.7367799804136	57	11	0.0932203389830508	118	992	3761,6331,153,6262,3752,481,7168,6641,23236,478,144245	KCNJ4,SCN5A,ADRB1,RYR2,KCND3,ATP1B1,TPM1,SNTB1,PLCB1,ATP1A3,ALG10B
SMP00329	Mexiletine Action Pathway	0.0647785997841195	-2.7367799804136	57	11	0.0932203389830508	118	992	3761,6331,153,6262,3752,481,7168,6641,23236,478,144245	KCNJ4,SCN5A,ADRB1,RYR2,KCND3,ATP1B1,TPM1,SNTB1,PLCB1,ATP1A3,ALG10B
SMP00302	Metoprolol Action Pathway	0.0647785997841195	-2.7367799804136	57	11	0.0932203389830508	118	992	3761,6331,153,6262,481,3752,7168,6641,23236,478,144245	KCNJ4,SCN5A,ADRB1,RYR2,ATP1B1,KCND3,TPM1,SNTB1,PLCB1,ATP1A3,ALG10B
SMP00300	Bisoprolol Action Pathway	0.0647785997841195	-2.7367799804136	57	11	0.0932203389830508	118	992	3761,6331,153,6262,3752,481,7168,6641,23236,478,144245	KCNJ4,SCN5A,ADRB1,RYR2,KCND3,ATP1B1,TPM1,SNTB1,PLCB1,ATP1A3,ALG10B
SMP00376	Amlodipine Action Pathway	0.0647785997841195	-2.7367799804136	57	11	0.0932203389830508	118	992	3761,6331,153,6262,3752,481,7168,6641,23236,478,144245	KCNJ4,SCN5A,ADRB1,RYR2,KCND3,ATP1B1,TPM1,SNTB1,PLCB1,ATP1A3,ALG10B
SMP00301	Esmolol Action Pathway	0.0647785997841195	-2.7367799804136	57	11	0.0932203389830508	118	992	3761,6331,153,6262,3752,481,7168,6641,23236,478,144245	KCNJ4,SCN5A,ADRB1,RYR2,KCND3,ATP1B1,TPM1,SNTB1,PLCB1,ATP1A3,ALG10B
SMP00299	Betaxolol Action Pathway	0.0647785997841195	-2.7367799804136	57	11	0.0932203389830508	118	992	3761,6331,153,6262,3752,481,7168,6641,23236,478,144245	KCNJ4,SCN5A,ADRB1,RYR2,KCND3,ATP1B1,TPM1,SNTB1,PLCB1,ATP1A3,ALG10B
SMP00330	Tocainide Action Pathway	0.0647785997841195	-2.7367799804136	57	11	0.0932203389830508	118	992	3761,6331,153,6262,3752,481,7168,6641,23236,478,144245	KCNJ4,SCN5A,ADRB1,RYR2,KCND3,ATP1B1,TPM1,SNTB1,PLCB1,ATP1A3,ALG10B
SMP00307	Propranolol Action Pathway	0.0647785997841195	-2.7367799804136	57	11	0.0932203389830508	118	992	3761,6331,153,6262,3752,481,7168,6641,23236,478,144245	KCNJ4,SCN5A,ADRB1,RYR2,KCND3,ATP1B1,TPM1,SNTB1,PLCB1,ATP1A3,ALG10B
SMP00326	Fosphenytoin (Antiarrhythmic) Action Pathway	0.0647785997841195	-2.7367799804136	57	11	0.0932203389830508	118	992	3761,6331,153,6262,3752,481,7168,6641,23236,478,144245	KCNJ4,SCN5A,ADRB1,RYR2,KCND3,ATP1B1,TPM1,SNTB1,PLCB1,ATP1A3,ALG10B
SMP00666	Levobunolol Action Pathway	0.0647785997841195	-2.7367799804136	57	11	0.0932203389830508	118	992	3761,6331,153,6262,3752,481,7168,6641,23236,478,144245	KCNJ4,SCN5A,ADRB1,RYR2,KCND3,ATP1B1,TPM1,SNTB1,PLCB1,ATP1A3,ALG10B
SMP00668	Bevantolol Action Pathway	0.0647785997841195	-2.7367799804136	57	11	0.0932203389830508	118	992	3761,6331,153,6262,3752,481,7168,6641,23236,478,144245	KCNJ4,SCN5A,ADRB1,RYR2,KCND3,ATP1B1,TPM1,SNTB1,PLCB1,ATP1A3,ALG10B
SMP00618	Fosphenytoin (Antiarrhythmic) Metabolism Pathway	0.0716721894453342	-2.63565248046379	4	2	0.0169491525423729	118	992	6331,6641	SCN5A,SNTB1
SMP00076	Thiamine Metabolism	0.0716721894453342	-2.63565248046379	4	2	0.0169491525423729	118	992	10560,27010	SLC19A2,TPK1
SMP00368	Labetalol Action Pathway	0.0720530983886575	-2.63035195414884	58	11	0.0932203389830508	118	992	3761,6331,153,6262,3752,481,7168,6641,23236,478,144245	KCNJ4,SCN5A,ADRB1,RYR2,KCND3,ATP1B1,TPM1,SNTB1,PLCB1,ATP1A3,ALG10B
SMP00367	Carvedilol Action Pathway	0.0720530983886575	-2.63035195414884	58	11	0.0932203389830508	118	992	3761,6331,153,6262,3752,481,7168,6641,23236,478,144245	KCNJ4,SCN5A,ADRB1,RYR2,KCND3,ATP1B1,TPM1,SNTB1,PLCB1,ATP1A3,ALG10B
SMP00048	Nicotinate and Nicotinamide Metabolism	0.0739578217101533	-2.60426032516637	14	4	0.0338983050847458	118	992	5167,4860,83594,23475	ENPP1,PNP,NUDT12,QPRT
SMP00067	Aspartate Metabolism	0.0739578217101533	-2.60426032516637	14	4	0.0338983050847458	118	992	445,440,18,122622	ASS1,ASNS,ABAT,ADSSL1
SMP00175	Canavan Disease	0.0739578217101533	-2.60426032516637	14	4	0.0338983050847458	118	992	445,440,18,122622	ASS1,ASNS,ABAT,ADSSL1
SMP00192	Hypoacetylaspartia	0.0739578217101533	-2.60426032516637	14	4	0.0338983050847458	118	992	445,440,18,122622	ASS1,ASNS,ABAT,ADSSL1
SMP00328	Lidocaine (Antiarrhythmic) Action Pathway	0.0798361239076481	-2.52777919640833	59	11	0.0932203389830508	118	992	3761,6331,153,6262,3752,481,7168,6641,23236,478,144245	KCNJ4,SCN5A,ADRB1,RYR2,KCND3,ATP1B1,TPM1,SNTB1,PLCB1,ATP1A3,ALG10B
SMP00311	Excitatory Neural Signalling Through 5-HTR 7 and  Serotonin 	0.0806142505324241	-2.51807983948462	9	3	0.0254237288135593	118	992	3363,55970,5567	HTR7,GNG12,PRKACB
SMP00128	Gluconeogenesis	0.109676254051144	-2.21022239774728	22	5	0.0423728813559322	118	992	2597,2023,226,53354,3099	GAPDH,ENO1,ALDOA,PANK1,HK2
SMP00581	Glycogenosis- Type IA. Von gierke disease	0.109676254051144	-2.21022239774728	22	5	0.0423728813559322	118	992	2597,2023,226,53354,3099	GAPDH,ENO1,ALDOA,PANK1,HK2
SMP00574	Glycogenosis- Type IC	0.109676254051144	-2.21022239774728	22	5	0.0423728813559322	118	992	2597,2023,226,53354,3099	GAPDH,ENO1,ALDOA,PANK1,HK2
SMP00563	Triosephosphate isomerase	0.109676254051144	-2.21022239774728	22	5	0.0423728813559322	118	992	2597,2023,226,53354,3099	GAPDH,ENO1,ALDOA,PANK1,HK2
SMP00562	Fructose-1-6-diphosphatase deficiency	0.109676254051144	-2.21022239774728	22	5	0.0423728813559322	118	992	2597,2023,226,53354,3099	GAPDH,ENO1,ALDOA,PANK1,HK2
SMP00374	Glycogen Storage Disease Type 1A (GSD1A) or Von Gierke Disease	0.109676254051144	-2.21022239774728	22	5	0.0423728813559322	118	992	2597,2023,226,53354,3099	GAPDH,ENO1,ALDOA,PANK1,HK2
SMP00560	Phosphoenolpyruvate carboxykinase deficiency 1 (PEPCK1)	0.109676254051144	-2.21022239774728	22	5	0.0423728813559322	118	992	2597,2023,226,53354,3099	GAPDH,ENO1,ALDOA,PANK1,HK2
SMP00573	Glycogenosis- Type IB	0.109676254051144	-2.21022239774728	22	5	0.0423728813559322	118	992	2597,2023,226,53354,3099	GAPDH,ENO1,ALDOA,PANK1,HK2
SMP00018	Alpha Linolenic Acid and Linoleic Acid Metabolism	0.110308554802871	-2.20447379632073	5	2	0.0169491525423729	118	992	3992,6785	FADS1,ELOVL4
SMP00310	Corticotropin Activation of Cortisol Production	0.110308554802871	-2.20447379632073	5	2	0.0169491525423729	118	992	55970,5567	GNG12,PRKACB
SMP00555	Glycogenosis- Type VI. Hers disease	0.111724252111822	-2.19172147819422	16	4	0.0338983050847458	118	992	283209,178,7358,3099	PGM2L1,AGL,UGDH,HK2
SMP00058	Starch and Sucrose Metabolism	0.111724252111822	-2.19172147819422	16	4	0.0338983050847458	118	992	283209,178,7358,3099	PGM2L1,AGL,UGDH,HK2
SMP00557	Sucrase-isomaltase deficiency	0.111724252111822	-2.19172147819422	16	4	0.0338983050847458	118	992	283209,178,7358,3099	PGM2L1,AGL,UGDH,HK2
SMP00556	Mucopolysaccharidosis VI. Sly syndrome	0.111724252111822	-2.19172147819422	16	4	0.0338983050847458	118	992	283209,178,7358,3099	PGM2L1,AGL,UGDH,HK2
SMP00552	Glycogen synthetase deficiency	0.111724252111822	-2.19172147819422	16	4	0.0338983050847458	118	992	283209,178,7358,3099	PGM2L1,AGL,UGDH,HK2
SMP00263	Cilostazol Action Pathway	0.118951612903345	-2.1290384828182	1	1	0.00847457627118644	118	992	5144	PDE4D
SMP00264	Dipyridamole (Antiplatelet) Action Pathway	0.118951612903345	-2.1290384828182	1	1	0.00847457627118644	118	992	5144	PDE4D
SMP00029	Selenoamino Acid Metabolism	0.132921397360756	-2.01799732275567	11	3	0.0254237288135593	118	992	875,4141,1491	CBS,MARS,CTH
SMP00343	Intracellular Signalling Through PGD2 receptor and Prostaglandin D2	0.152927949719763	-1.87778838537016	6	2	0.0169491525423729	118	992	55970,5567	GNG12,PRKACB
SMP00308	Dopamine Activation of Neurological Reward System	0.152927949719763	-1.87778838537016	6	2	0.0169491525423729	118	992	55970,5567	GNG12,PRKACB
SMP00027	Pantothenate and CoA Biosynthesis	0.152927949719763	-1.87778838537016	6	2	0.0169491525423729	118	992	5167,53354	ENPP1,PANK1
SMP00554	Glycogenosis- Type IV. Amylopectinosis	0.162529558850758	-1.81689539313421	12	3	0.0254237288135593	118	992	283209,178,7358	PGM2L1,AGL,UGDH
SMP00553	Glycogenosis- Type III. Cori disease	0.162529558850758	-1.81689539313421	12	3	0.0254237288135593	118	992	283209,178,7358	PGM2L1,AGL,UGDH
SMP00358	Fc Epsilon Receptor I Signaling in Mast Cells	0.170430426277209	-1.76942812256165	32	6	0.0508474576271186	118	992	5321,10451,5163,5578,5608,6850	PLA2G4A,VAV3,PDK1,PRKCA,MAP2K6,SYK
SMP00340	Methylenetetrahydrofolate Reductase Deficiency (MTHFRD)	0.180841817662837	-1.71013256538507	19	4	0.0338983050847458	118	992	253827,875,4141,1491	MSRB3,CBS,MARS,CTH
SMP00214	S-Adenosylhomocysteine (SAH) Hydrolase Deficiency	0.180841817662837	-1.71013256538507	19	4	0.0338983050847458	118	992	875,253827,4141,1491	CBS,MSRB3,MARS,CTH
SMP00221	Methionine Adenosyltransferase Deficiency	0.180841817662837	-1.71013256538507	19	4	0.0338983050847458	118	992	253827,875,4141,1491	MSRB3,CBS,MARS,CTH
SMP00177	Cystathionine Beta-Synthase Deficiency	0.180841817662837	-1.71013256538507	19	4	0.0338983050847458	118	992	253827,875,4141,1491	MSRB3,CBS,MARS,CTH
SMP00341	Hypermethioninemia	0.180841817662837	-1.71013256538507	19	4	0.0338983050847458	118	992	875,253827,4141,1491	CBS,MSRB3,MARS,CTH
SMP00033	Methionine Metabolism	0.180841817662837	-1.71013256538507	19	4	0.0338983050847458	118	992	253827,875,4141,1491	MSRB3,CBS,MARS,CTH
SMP00222	Glycine N-methyltransferase Deficiency	0.180841817662837	-1.71013256538507	19	4	0.0338983050847458	118	992	253827,875,4141,1491	MSRB3,CBS,MARS,CTH
SMP00570	Homocystinuria-megaloblastic anemia due to defect in cobalamin metabolism- cblG complementation type	0.180841817662837	-1.71013256538507	19	4	0.0338983050847458	118	992	253827,875,4141,1491	MSRB3,CBS,MARS,CTH
SMP00037	Lysine Degradation	0.193890040102701	-1.64046408420701	13	3	0.0254237288135593	118	992	6542,51166,10157	SLC7A2,AADAT,AASS
SMP00186	Glutaric Aciduria Type I	0.193890040102701	-1.64046408420701	13	3	0.0254237288135593	118	992	6542,51166,10157	SLC7A2,AADAT,AASS
SMP00528	Hyperlysinemia II or Saccharopinuria	0.193890040102701	-1.64046408420701	13	3	0.0254237288135593	118	992	6542,51166,10157	SLC7A2,AADAT,AASS
SMP00527	Hyperlysinemia I- Familial	0.193890040102701	-1.64046408420701	13	3	0.0254237288135593	118	992	6542,51166,10157	SLC7A2,AADAT,AASS
SMP00239	Saccharopinuria/Hyperlysinemia II	0.193890040102701	-1.64046408420701	13	3	0.0254237288135593	118	992	6542,51166,10157	SLC7A2,AADAT,AASS
SMP00719	2-aminoadipic 2-oxoadipic aciduria	0.193890040102701	-1.64046408420701	13	3	0.0254237288135593	118	992	6542,51166,10157	SLC7A2,AADAT,AASS
SMP00571	Pyridoxine dependency with seizures	0.193890040102701	-1.64046408420701	13	3	0.0254237288135593	118	992	6542,51166,10157	SLC7A2,AADAT,AASS
SMP00322	Vasopressin Regulation of Water Homeostasis	0.198054367867336	-1.61921370079065	7	2	0.0169491525423729	118	992	55970,5567	GNG12,PRKACB
SMP00078	Chlorothiazide Action Pathway	0.208667599251877	-1.56701272730194	34	6	0.0508474576271186	118	992	481,6520,9990,4306,478,8140	ATP1B1,SLC3A2,SLC12A6,NR3C2,ATP1A3,SLC7A5
SMP00088	Bumetanide Action Pathway	0.208667599251877	-1.56701272730194	34	6	0.0508474576271186	118	992	9990,481,6520,4306,478,8140	SLC12A6,ATP1B1,SLC3A2,NR3C2,ATP1A3,SLC7A5
SMP00115	Furosemide Action Pathway	0.208667599251877	-1.56701272730194	34	6	0.0508474576271186	118	992	481,6520,9990,4306,478,8140	ATP1B1,SLC3A2,SLC12A6,NR3C2,ATP1A3,SLC7A5
SMP00105	Metolazone Action Pathway	0.208667599251877	-1.56701272730194	34	6	0.0508474576271186	118	992	481,6520,9990,4306,478,8140	ATP1B1,SLC3A2,SLC12A6,NR3C2,ATP1A3,SLC7A5
SMP00197	Lysinuric Protein Intolerance	0.208667599251877	-1.56701272730194	34	6	0.0508474576271186	118	992	481,6520,9990,4306,478,8140	ATP1B1,SLC3A2,SLC12A6,NR3C2,ATP1A3,SLC7A5
SMP00245	Glucose Transporter Defect (SGLT2)	0.208667599251877	-1.56701272730194	34	6	0.0508474576271186	118	992	481,6520,9990,4306,478,8140	ATP1B1,SLC3A2,SLC12A6,NR3C2,ATP1A3,SLC7A5
SMP00090	Bendroflumethiazide Action Pathway	0.208667599251877	-1.56701272730194	34	6	0.0508474576271186	118	992	481,6520,9990,4306,478,8140	ATP1B1,SLC3A2,SLC12A6,NR3C2,ATP1A3,SLC7A5
SMP00100	Hydrochlorothiazide Action Pathway	0.208667599251877	-1.56701272730194	34	6	0.0508474576271186	118	992	481,6520,9990,4306,478,8140	ATP1B1,SLC3A2,SLC12A6,NR3C2,ATP1A3,SLC7A5
SMP00583	Blue diaper syndrome	0.208667599251877	-1.56701272730194	34	6	0.0508474576271186	118	992	9990,481,6520,4306,478,8140	SLC12A6,ATP1B1,SLC3A2,NR3C2,ATP1A3,SLC7A5
SMP00135	Eplerenone Action Pathway	0.208667599251877	-1.56701272730194	34	6	0.0508474576271186	118	992	481,6520,9990,4306,478,8140	ATP1B1,SLC3A2,SLC12A6,NR3C2,ATP1A3,SLC7A5
SMP00483	Kidney Function	0.208667599251877	-1.56701272730194	34	6	0.0508474576271186	118	992	481,6520,9990,4306,478,8140	ATP1B1,SLC3A2,SLC12A6,NR3C2,ATP1A3,SLC7A5
SMP00081	Methyclothiazide Action Pathway	0.208667599251877	-1.56701272730194	34	6	0.0508474576271186	118	992	481,6520,9990,4306,478,8140	ATP1B1,SLC3A2,SLC12A6,NR3C2,ATP1A3,SLC7A5
SMP00108	Hydroflumethiazide Action Pathway	0.208667599251877	-1.56701272730194	34	6	0.0508474576271186	118	992	481,6520,9990,4306,478,8140	ATP1B1,SLC3A2,SLC12A6,NR3C2,ATP1A3,SLC7A5
SMP00723	Cystinuria	0.208667599251877	-1.56701272730194	34	6	0.0508474576271186	118	992	481,6520,9990,4306,478,8140	ATP1B1,SLC3A2,SLC12A6,NR3C2,ATP1A3,SLC7A5
SMP00134	Spironolactone Action Pathway	0.208667599251877	-1.56701272730194	34	6	0.0508474576271186	118	992	481,6520,9990,4306,478,8140	ATP1B1,SLC3A2,SLC12A6,NR3C2,ATP1A3,SLC7A5
SMP00118	Torsemide Action Pathway	0.208667599251877	-1.56701272730194	34	6	0.0508474576271186	118	992	481,6520,9990,4306,478,8140	ATP1B1,SLC3A2,SLC12A6,NR3C2,ATP1A3,SLC7A5
SMP00189	Hartnup Disorder	0.208667599251877	-1.56701272730194	34	6	0.0508474576271186	118	992	9990,481,6520,4306,478,8140	SLC12A6,ATP1B1,SLC3A2,NR3C2,ATP1A3,SLC7A5
SMP00133	Amiloride Action Pathway	0.208667599251877	-1.56701272730194	34	6	0.0508474576271186	118	992	481,6520,9990,4306,478,8140	ATP1B1,SLC3A2,SLC12A6,NR3C2,ATP1A3,SLC7A5
SMP00184	Glucose Transporter Defect (SGLT2)	0.208667599251877	-1.56701272730194	34	6	0.0508474576271186	118	992	481,6520,9990,4306,478,8140	ATP1B1,SLC3A2,SLC12A6,NR3C2,ATP1A3,SLC7A5
SMP00097	Ethacrynic Acid Action Pathway	0.208667599251877	-1.56701272730194	34	6	0.0508474576271186	118	992	481,6520,9990,4306,478,8140	ATP1B1,SLC3A2,SLC12A6,NR3C2,ATP1A3,SLC7A5
SMP00091	Quinethazone Action Pathway	0.208667599251877	-1.56701272730194	34	6	0.0508474576271186	118	992	9990,481,6520,4306,478,8140	SLC12A6,ATP1B1,SLC3A2,NR3C2,ATP1A3,SLC7A5
SMP00585	Lysinuric protein intolerance (LPI)	0.208667599251877	-1.56701272730194	34	6	0.0508474576271186	118	992	481,6520,9990,4306,478,8140	ATP1B1,SLC3A2,SLC12A6,NR3C2,ATP1A3,SLC7A5
SMP00132	Triamterene Action Pathway	0.208667599251877	-1.56701272730194	34	6	0.0508474576271186	118	992	481,6520,9990,4306,478,8140	ATP1B1,SLC3A2,SLC12A6,NR3C2,ATP1A3,SLC7A5
SMP00103	Cyclothiazide Action Pathway	0.208667599251877	-1.56701272730194	34	6	0.0508474576271186	118	992	481,6520,9990,4306,478,8140	ATP1B1,SLC3A2,SLC12A6,NR3C2,ATP1A3,SLC7A5
SMP00110	Indapamide Action Pathway	0.208667599251877	-1.56701272730194	34	6	0.0508474576271186	118	992	481,6520,9990,4306,478,8140	ATP1B1,SLC3A2,SLC12A6,NR3C2,ATP1A3,SLC7A5
SMP00193	Iminoglycinuria	0.208667599251877	-1.56701272730194	34	6	0.0508474576271186	118	992	9990,481,6520,4306,478,8140	SLC12A6,ATP1B1,SLC3A2,NR3C2,ATP1A3,SLC7A5
SMP00121	Trichlormethiazide Action Pathway	0.208667599251877	-1.56701272730194	34	6	0.0508474576271186	118	992	9990,481,6520,4306,478,8140	SLC12A6,ATP1B1,SLC3A2,NR3C2,ATP1A3,SLC7A5
SMP00080	Polythiazide Action Pathway	0.208667599251877	-1.56701272730194	34	6	0.0508474576271186	118	992	9990,481,6520,4306,478,8140	SLC12A6,ATP1B1,SLC3A2,NR3C2,ATP1A3,SLC7A5
SMP00122	Chlorthalidone Action Pathway	0.208667599251877	-1.56701272730194	34	6	0.0508474576271186	118	992	9990,481,6520,4306,478,8140	SLC12A6,ATP1B1,SLC3A2,NR3C2,ATP1A3,SLC7A5
SMP00456	Fatty Acid Biosynthesis	0.2238594935026	-1.49673668508678	2	1	0.00847457627118644	118	992	2194	FASN
SMP00044	Histidine Metabolism	0.226598826937271	-1.48457410720096	14	3	0.0254237288135593	118	992	4128,217,144193	MAOA,ALDH2,AMDHD1
SMP00191	Histidinemia	0.226598826937271	-1.48457410720096	14	3	0.0254237288135593	118	992	4128,217,144193	MAOA,ALDH2,AMDHD1
SMP00462	Inositol Phosphate Metabolism	0.226598826937271	-1.48457410720096	14	3	0.0254237288135593	118	992	51477,3628,8821	ISYNA1,INPP1,INPP4B
SMP00030	Oxidation of Branched Chain Fatty Acids	0.244501745463025	-1.40853283118462	8	2	0.0169491525423729	118	992	217,2180	ALDH2,ACSL1
SMP00354	Intracellular Signalling Through Prostacyclin Receptor and Prostacyclin	0.244501745463025	-1.40853283118462	8	2	0.0169491525423729	118	992	55970,5567	GNG12,PRKACB
SMP00203	Molybdenum Cofactor Deficiency	0.270983196434771	-1.30569846580063	37	6	0.0508474576271186	118	992	203,5144,2977,4860,10846,270	AK1,PDE4D,GUCY1A2,PNP,PDE10A,AMPD1
SMP00167	Adenylosuccinate Lyase Deficiency	0.270983196434771	-1.30569846580063	37	6	0.0508474576271186	118	992	203,5144,2977,4860,10846,270	AK1,PDE4D,GUCY1A2,PNP,PDE10A,AMPD1
SMP00365	Gout or Kelley-Seegmiller Syndrome	0.270983196434771	-1.30569846580063	37	6	0.0508474576271186	118	992	203,5144,2977,4860,10846,270	AK1,PDE4D,GUCY1A2,PNP,PDE10A,AMPD1
SMP00220	Xanthine Dehydrogenase Deficiency (Xanthinuria)	0.270983196434771	-1.30569846580063	37	6	0.0508474576271186	118	992	203,5144,2977,4860,10846,270	AK1,PDE4D,GUCY1A2,PNP,PDE10A,AMPD1
SMP00537	Myoadenylate deaminase deficiency	0.270983196434771	-1.30569846580063	37	6	0.0508474576271186	118	992	203,5144,2977,4860,10846,270	AK1,PDE4D,GUCY1A2,PNP,PDE10A,AMPD1
SMP00050	Purine Metabolism	0.270983196434771	-1.30569846580063	37	6	0.0508474576271186	118	992	203,5144,2977,4860,10846,270	AK1,PDE4D,GUCY1A2,PNP,PDE10A,AMPD1
SMP00144	Adenosine Deaminase Deficiency	0.270983196434771	-1.30569846580063	37	6	0.0508474576271186	118	992	203,5144,2977,4860,10846,270	AK1,PDE4D,GUCY1A2,PNP,PDE10A,AMPD1
SMP00536	Mitochondrial DNA depletion syndrome	0.270983196434771	-1.30569846580063	37	6	0.0508474576271186	118	992	203,5144,2977,4860,10846,270	AK1,PDE4D,GUCY1A2,PNP,PDE10A,AMPD1
SMP00535	Adenine phosphoribosyltransferase deficiency (APRT)	0.270983196434771	-1.30569846580063	37	6	0.0508474576271186	118	992	203,5144,2977,4860,10846,270	AK1,PDE4D,GUCY1A2,PNP,PDE10A,AMPD1
SMP00512	Xanthinuria type I	0.270983196434771	-1.30569846580063	37	6	0.0508474576271186	118	992	203,5144,2977,4860,10846,270	AK1,PDE4D,GUCY1A2,PNP,PDE10A,AMPD1
SMP00513	Xanthinuria type II	0.270983196434771	-1.30569846580063	37	6	0.0508474576271186	118	992	203,5144,2977,4860,10846,270	AK1,PDE4D,GUCY1A2,PNP,PDE10A,AMPD1
SMP00210	Purine Nucleoside Phosphorylase Deficiency	0.270983196434771	-1.30569846580063	37	6	0.0508474576271186	118	992	203,5144,2977,4860,10846,270	AK1,PDE4D,GUCY1A2,PNP,PDE10A,AMPD1
SMP00364	Lesch-Nyhan Syndrome (LNS)	0.270983196434771	-1.30569846580063	37	6	0.0508474576271186	118	992	203,5144,2977,4860,10846,270	AK1,PDE4D,GUCY1A2,PNP,PDE10A,AMPD1
SMP00168	AICA-Ribosiduria	0.270983196434771	-1.30569846580063	37	6	0.0508474576271186	118	992	203,5144,2977,4860,10846,270	AK1,PDE4D,GUCY1A2,PNP,PDE10A,AMPD1
SMP00335	Intracellular Signalling Through Histamine H2 Receptor and Histamine	0.291326744014919	-1.23330981004826	9	2	0.0169491525423729	118	992	55970,5567	GNG12,PRKACB
SMP00351	GABA-Transaminase Deficiency	0.291326744014919	-1.23330981004826	9	2	0.0169491525423729	118	992	217,18	ALDH2,ABAT
SMP00499	Beta-mercaptolactate-cysteine disulfiduria	0.291326744014919	-1.23330981004826	9	2	0.0169491525423729	118	992	833,1491	CARS,CTH
SMP00333	Intracellular Signalling Through FSH Receptor and Follicle Stimulating Hormone	0.291326744014919	-1.23330981004826	9	2	0.0169491525423729	118	992	55970,5567	GNG12,PRKACB
SMP00013	Cysteine Metabolism	0.291326744014919	-1.23330981004826	9	2	0.0169491525423729	118	992	833,1491	CARS,CTH
SMP00492	Ureidopropionase deficiency	0.291326744014919	-1.23330981004826	9	2	0.0169491525423729	118	992	217,18	ALDH2,ABAT
SMP00722	Cystinosis- ocular nonnephropathic	0.291326744014919	-1.23330981004826	9	2	0.0169491525423729	118	992	833,1491	CARS,CTH
SMP00312	Excitatory Neural Signalling Through 5-HTR 6 and Serotonin 	0.291326744014919	-1.23330981004826	9	2	0.0169491525423729	118	992	55970,5567	GNG12,PRKACB
SMP00493	Carnosinuria- carnosinemia	0.291326744014919	-1.23330981004826	9	2	0.0169491525423729	118	992	217,18	ALDH2,ABAT
SMP00309	Excitatory Neural Signalling Through 5-HTR 4 and Serotonin	0.291326744014919	-1.23330981004826	9	2	0.0169491525423729	118	992	55970,5567	GNG12,PRKACB
SMP00007	Beta-Alanine Metabolism	0.291326744014919	-1.23330981004826	9	2	0.0169491525423729	118	992	217,18	ALDH2,ABAT
SMP00320	Intracellular Signalling Through Adenosine Receptor A2a and Adenosine	0.292748134556897	-1.2284426486616	38	6	0.0508474576271186	118	992	5058,1147,55970,5608,9693,5567	PAK1,CHUK,GNG12,MAP2K6,RAPGEF2,PRKACB
SMP00321	Intracellular Signalling Through Adenosine Receptor A2b and Adenosine	0.292748134556897	-1.2284426486616	38	6	0.0508474576271186	118	992	5058,1147,55970,5608,9693,5567	PAK1,CHUK,GNG12,MAP2K6,RAPGEF2,PRKACB
SMP00327	Phenytoin (Antiarrhythmic) Action Pathway	0.301200176609013	-1.19998019670527	77	11	0.0932203389830508	118	992	3761,6331,153,6262,481,3752,7168,6641,23236,478,144245	KCNJ4,SCN5A,ADRB1,RYR2,ATP1B1,KCND3,TPM1,SNTB1,PLCB1,ATP1A3,ALG10B
SMP00124	Glycerol Phosphate Shuttle	0.316369170037058	-1.15084548766851	3	1	0.00847457627118644	118	992	2597	GAPDH
SMP00459	Pyruvaldehyde Degradation	0.316369170037058	-1.15084548766851	3	1	0.00847457627118644	118	992	197257	LDHD
SMP00428	Mercaptopurine Action Pathway	0.321613952386133	-1.13440335833316	47	7	0.0593220338983051	118	992	203,5144,2977,4860,10257,10846,270	AK1,PDE4D,GUCY1A2,PNP,ABCC4,PDE10A,AMPD1
SMP00430	Thioguanine Action Pathway	0.321613952386133	-1.13440335833316	47	7	0.0593220338983051	118	992	203,5144,2977,10257,4860,10846,270	AK1,PDE4D,GUCY1A2,ABCC4,PNP,PDE10A,AMPD1
SMP00427	Azathioprine Action Pathway	0.321613952386133	-1.13440335833316	47	7	0.0593220338983051	118	992	203,5144,2977,10257,4860,10846,270	AK1,PDE4D,GUCY1A2,ABCC4,PNP,PDE10A,AMPD1
SMP00338	Intracellular Signalling Through LHCGR Receptor and Luteinizing Hormone/Choriogonadotropin	0.337788527293384	-1.08533523820063	10	2	0.0169491525423729	118	992	55970,5567	GNG12,PRKACB
SMP00015	Glutathione Metabolism	0.383314556167843	-0.958899331402677	11	2	0.0169491525423729	118	992	26873,119391	OPLAH,GSTO2
SMP00500	5-oxoprolinase deficiency	0.383314556167843	-0.958899331402677	11	2	0.0169491525423729	118	992	26873,119391	OPLAH,GSTO2
SMP00337	Glutathione Synthetase Deficiency	0.383314556167843	-0.958899331402677	11	2	0.0169491525423729	118	992	26873,119391	OPLAH,GSTO2
SMP00009	Ammonia Recycling	0.383314556167843	-0.958899331402677	11	2	0.0169491525423729	118	992	440,2731	ASNS,GLDC
SMP00143	5-Oxoprolinuria	0.383314556167843	-0.958899331402677	11	2	0.0169491525423729	118	992	26873,119391	OPLAH,GSTO2
SMP00501	Gamma-glutamyl-transpeptidase deficiency	0.383314556167843	-0.958899331402677	11	2	0.0169491525423729	118	992	26873,119391	OPLAH,GSTO2
SMP00183	Gamma-Glutamyltransferase Deficiency	0.383314556167843	-0.958899331402677	11	2	0.0169491525423729	118	992	26873,119391	OPLAH,GSTO2
SMP00623	Heroin Metabolism Pathway	0.397934830235592	-0.921467030231723	4	1	0.00847457627118644	118	992	590	BCHE
SMP00620	Lidocaine (Local Anaesthetic) Metabolism Pathway	0.397934830235592	-0.921467030231723	4	1	0.00847457627118644	118	992	6324	SCN1B
SMP00450	Phytanic Acid Peroxisomal Oxidation	0.397934830235592	-0.921467030231723	4	1	0.00847457627118644	118	992	11001	SLC27A2
SMP00629	Adefovir Dipivoxil Metabolism Pathway	0.397934830235592	-0.921467030231723	4	1	0.00847457627118644	118	992	203	AK1
SMP00451	Refsum Disease	0.397934830235592	-0.921467030231723	4	1	0.00847457627118644	118	992	11001	SLC27A2
SMP00630	Tenofovir Metabolism Pathway	0.397934830235592	-0.921467030231723	4	1	0.00847457627118644	118	992	203	AK1
SMP00458	Lactose Intolerance	0.427471555631347	-0.849867529353837	12	2	0.0169491525423729	118	992	481,478	ATP1B1,ATP1A3
SMP00457	Lactose Degradation	0.427471555631347	-0.849867529353837	12	2	0.0169491525423729	118	992	481,478	ATP1B1,ATP1A3
SMP00582	Joubert syndrome	0.431725358745097	-0.839965636554317	20	3	0.0254237288135593	118	992	9896,23236,8821	FIG4,PLCB1,INPP4B
SMP00463	Phosphatidylinositol Phosphate Metabolism	0.431725358745097	-0.839965636554317	20	3	0.0254237288135593	118	992	9896,23236,8821	FIG4,PLCB1,INPP4B
SMP00407	Heroin Action Pathway	0.45970392107912	-0.777172646558475	29	4	0.0338983050847458	118	992	481,590,6324,478	ATP1B1,BCHE,SCN1B,ATP1A3
SMP00011	Inositol Metabolism	0.464821583612434	-0.766101638179122	21	3	0.0254237288135593	118	992	9896,51477,3628	FIG4,ISYNA1,INPP1
SMP00055	Alanine Metabolism	0.469841399094936	-0.755360089960847	5	1	0.00847457627118644	118	992	16	AARS
SMP00070	Riboflavin Metabolism	0.469841399094936	-0.755360089960847	5	1	0.00847457627118644	118	992	5167	ENPP1
SMP00352	Primary Hyperoxaluria Type I	0.469841399094936	-0.755360089960847	5	1	0.00847457627118644	118	992	16	AARS
SMP00516	Adrenoleukodystrophy- X-linked	0.469841399094936	-0.755360089960847	5	1	0.00847457627118644	118	992	2180	ACSL1
SMP00350	Pyruvate Carboxylase Deficiency	0.469841399094936	-0.755360089960847	5	1	0.00847457627118644	118	992	16	AARS
SMP00469	Capecitabine Action Pathway	0.469841399094936	-0.755360089960847	5	1	0.00847457627118644	118	992	1890	TYMP
SMP00052	Beta Oxidation of Very Long Chain Fatty Acids	0.469841399094936	-0.755360089960847	5	1	0.00847457627118644	118	992	2180	ACSL1
SMP00607	Capecitabine Metabolism Pathway	0.469841399094936	-0.755360089960847	5	1	0.00847457627118644	118	992	1890	TYMP
SMP00313	Lactic Acidemia	0.469841399094936	-0.755360089960847	5	1	0.00847457627118644	118	992	16	AARS
SMP00517	Carnitine-acylcarnitine translocase deficiency	0.469841399094936	-0.755360089960847	5	1	0.00847457627118644	118	992	2180	ACSL1
SMP00467	Trehalose Degradation	0.469940922091653	-0.755148289855983	13	2	0.0169491525423729	118	992	481,478	ATP1B1,ATP1A3
SMP00002	Carbamoyl Phosphate Synthetase Deficiency	0.469940922091653	-0.755148289855983	13	2	0.0169491525423729	118	992	445,6510	ASS1,SLC1A5
SMP00003	Argininosuccinic Aciduria	0.469940922091653	-0.755148289855983	13	2	0.0169491525423729	118	992	445,6510	ASS1,SLC1A5
SMP00205	Ornithine Transcarbamylase Deficiency (OTC Deficiency)	0.469940922091653	-0.755148289855983	13	2	0.0169491525423729	118	992	445,6510	ASS1,SLC1A5
SMP00357	Argininemia	0.469940922091653	-0.755148289855983	13	2	0.0169491525423729	118	992	445,6510	ASS1,SLC1A5
SMP00001	Citrullinemia Type I	0.469940922091653	-0.755148289855983	13	2	0.0169491525423729	118	992	445,6510	ASS1,SLC1A5
SMP00059	Urea Cycle	0.469940922091653	-0.755148289855983	13	2	0.0169491525423729	118	992	445,6510	ASS1,SLC1A5
SMP00424	Citalopram Action Pathway	0.540771099664063	-0.614759195651647	32	4	0.0338983050847458	118	992	4128,481,6324,478	MAOA,ATP1B1,SCN1B,ATP1A3
SMP00449	Ethanol Degradation	0.589085709156825	-0.529183589521745	7	1	0.00847457627118644	118	992	217	ALDH2
SMP00434	Paclitaxel Action Pathway	0.589085709156825	-0.529183589521745	7	1	0.00847457627118644	118	992	1244	ABCC2
SMP00627	Citalopram Metabolism Pathway	0.589085709156825	-0.529183589521745	7	1	0.00847457627118644	118	992	4128	MAOA
SMP00682	Leucine Stimulation on Insulin Signaling	0.589085709156825	-0.529183589521745	7	1	0.00847457627118644	118	992	8140	SLC7A5
SMP00637	Tramadol Metabolism Pathway	0.589085709156825	-0.529183589521745	7	1	0.00847457627118644	118	992	1244	ABCC2
SMP00435	Docetaxel Action Pathway	0.589085709156825	-0.529183589521745	7	1	0.00847457627118644	118	992	1244	ABCC2
SMP00674	Anileridine Action Pathway	0.615315100339527	-0.485620784110651	26	3	0.0254237288135593	118	992	481,6324,478	ATP1B1,SCN1B,ATP1A3
SMP00411	Hydrocodone Action Pathway	0.615315100339527	-0.485620784110651	26	3	0.0254237288135593	118	992	481,6324,478	ATP1B1,SCN1B,ATP1A3
SMP00689	Dihydromorphine Action Pathway	0.615315100339527	-0.485620784110651	26	3	0.0254237288135593	118	992	481,6324,478	ATP1B1,SCN1B,ATP1A3
SMP00687	Naltrexone Action Pathway	0.615315100339527	-0.485620784110651	26	3	0.0254237288135593	118	992	481,6324,478	ATP1B1,SCN1B,ATP1A3
SMP00675	Diphenoxylate Action Pathway	0.615315100339527	-0.485620784110651	26	3	0.0254237288135593	118	992	481,6324,478	ATP1B1,SCN1B,ATP1A3
SMP00417	Sufentanil Action Pathway	0.615315100339527	-0.485620784110651	26	3	0.0254237288135593	118	992	481,6324,478	ATP1B1,SCN1B,ATP1A3
SMP00686	Pentazocine Action Pathway	0.615315100339527	-0.485620784110651	26	3	0.0254237288135593	118	992	481,6324,478	ATP1B1,SCN1B,ATP1A3
SMP00404	Ropivacaine Action Pathway	0.615315100339527	-0.485620784110651	26	3	0.0254237288135593	118	992	481,6324,478	ATP1B1,SCN1B,ATP1A3
SMP00425	Escitalopram Action Pathway	0.615315100339527	-0.485620784110651	26	3	0.0254237288135593	118	992	481,6324,478	ATP1B1,SCN1B,ATP1A3
SMP00679	3-Methylthiofentanyl Action Pathway	0.615315100339527	-0.485620784110651	26	3	0.0254237288135593	118	992	481,6324,478	ATP1B1,SCN1B,ATP1A3
SMP00681	Ethylmorphine Action Pathway	0.615315100339527	-0.485620784110651	26	3	0.0254237288135593	118	992	481,6324,478	ATP1B1,SCN1B,ATP1A3
SMP00684	Buprenorphine Action Pathway	0.615315100339527	-0.485620784110651	26	3	0.0254237288135593	118	992	481,6324,478	ATP1B1,SCN1B,ATP1A3
SMP00672	Propoxyphene Action Pathway	0.615315100339527	-0.485620784110651	26	3	0.0254237288135593	118	992	481,6324,478	ATP1B1,SCN1B,ATP1A3
SMP00690	Ketobemidone  Action Pathway	0.615315100339527	-0.485620784110651	26	3	0.0254237288135593	118	992	481,6324,478	ATP1B1,SCN1B,ATP1A3
SMP00392	Benzocaine Action Pathway	0.615315100339527	-0.485620784110651	26	3	0.0254237288135593	118	992	481,6324,478	ATP1B1,SCN1B,ATP1A3
SMP00410	Hydromorphone Action Pathway	0.615315100339527	-0.485620784110651	26	3	0.0254237288135593	118	992	481,6324,478	ATP1B1,SCN1B,ATP1A3
SMP00399	Mepivacaine Action Pathway	0.615315100339527	-0.485620784110651	26	3	0.0254237288135593	118	992	481,6324,478	ATP1B1,SCN1B,ATP1A3
SMP00678	Methadyl Acetate Action Pathway	0.615315100339527	-0.485620784110651	26	3	0.0254237288135593	118	992	481,6324,478	ATP1B1,SCN1B,ATP1A3
SMP00416	Remifentanil Action Pathway	0.615315100339527	-0.485620784110651	26	3	0.0254237288135593	118	992	481,6324,478	ATP1B1,SCN1B,ATP1A3
SMP00671	Tramadol Action Action Pathway	0.615315100339527	-0.485620784110651	26	3	0.0254237288135593	118	992	481,6324,478	ATP1B1,SCN1B,ATP1A3
SMP00393	Bupivacaine Action Pathway	0.615315100339527	-0.485620784110651	26	3	0.0254237288135593	118	992	481,6324,478	ATP1B1,SCN1B,ATP1A3
SMP00396	Dibucaine Action Pathway	0.615315100339527	-0.485620784110651	26	3	0.0254237288135593	118	992	481,6324,478	ATP1B1,SCN1B,ATP1A3
SMP00415	Fentanyl Action Pathway	0.615315100339527	-0.485620784110651	26	3	0.0254237288135593	118	992	481,6324,478	ATP1B1,SCN1B,ATP1A3
SMP00673	Levorphanol Action Pathway	0.615315100339527	-0.485620784110651	26	3	0.0254237288135593	118	992	481,6324,478	ATP1B1,SCN1B,ATP1A3
SMP00401	Prilocaine Action Pathway	0.615315100339527	-0.485620784110651	26	3	0.0254237288135593	118	992	481,6324,478	ATP1B1,SCN1B,ATP1A3
SMP00685	Alvimopan Action Pathway	0.615315100339527	-0.485620784110651	26	3	0.0254237288135593	118	992	481,6324,478	ATP1B1,SCN1B,ATP1A3
SMP00400	Oxybuprocaine Action Pathway	0.615315100339527	-0.485620784110651	26	3	0.0254237288135593	118	992	481,6324,478	ATP1B1,SCN1B,ATP1A3
SMP00394	Chloroprocaine Action Pathway	0.615315100339527	-0.485620784110651	26	3	0.0254237288135593	118	992	481,6324,478	ATP1B1,SCN1B,ATP1A3
SMP00414	Carfentanil Action Pathway	0.615315100339527	-0.485620784110651	26	3	0.0254237288135593	118	992	481,6324,478	ATP1B1,SCN1B,ATP1A3
SMP00397	Levobupivacaine Action Pathway	0.615315100339527	-0.485620784110651	26	3	0.0254237288135593	118	992	481,6324,478	ATP1B1,SCN1B,ATP1A3
SMP00676	Dezocine Action Pathway	0.615315100339527	-0.485620784110651	26	3	0.0254237288135593	118	992	481,6324,478	ATP1B1,SCN1B,ATP1A3
SMP00413	Alfentanil Action Pathway	0.615315100339527	-0.485620784110651	26	3	0.0254237288135593	118	992	481,6324,478	ATP1B1,SCN1B,ATP1A3
SMP00395	Cocaine Action Pathway	0.615315100339527	-0.485620784110651	26	3	0.0254237288135593	118	992	481,6324,478	ATP1B1,SCN1B,ATP1A3
SMP00412	Oxymorphone Action Pathway	0.615315100339527	-0.485620784110651	26	3	0.0254237288135593	118	992	481,6324,478	ATP1B1,SCN1B,ATP1A3
SMP00688	Naloxone Action Pathway	0.615315100339527	-0.485620784110651	26	3	0.0254237288135593	118	992	481,6324,478	ATP1B1,SCN1B,ATP1A3
SMP00403	Proparacaine Action Pathway	0.615315100339527	-0.485620784110651	26	3	0.0254237288135593	118	992	481,6324,478	ATP1B1,SCN1B,ATP1A3
SMP00677	Levomethadyl Acetate Action Action Pathway	0.615315100339527	-0.485620784110651	26	3	0.0254237288135593	118	992	481,6324,478	ATP1B1,SCN1B,ATP1A3
SMP00683	Levallorphan Action Pathway	0.615315100339527	-0.485620784110651	26	3	0.0254237288135593	118	992	481,6324,478	ATP1B1,SCN1B,ATP1A3
SMP00402	Procaine Action Pathway	0.615315100339527	-0.485620784110651	26	3	0.0254237288135593	118	992	481,6324,478	ATP1B1,SCN1B,ATP1A3
SMP00680	Dimethylthiambutene Action Pathway	0.615315100339527	-0.485620784110651	26	3	0.0254237288135593	118	992	481,6324,478	ATP1B1,SCN1B,ATP1A3
SMP00409	Oxycodone Action Pathway	0.615315100339527	-0.485620784110651	26	3	0.0254237288135593	118	992	481,6324,478	ATP1B1,SCN1B,ATP1A3
SMP00654	Warburg Effect	0.617151205083291	-0.482641220135447	44	5	0.0423728813559322	118	992	2597,6510,2023,3099,48	GAPDH,SLC1A5,ENO1,HK2,ACO1
SMP00650	Doxorubicin Metabolism Pathway	0.619507079171278	-0.478831150744529	17	2	0.0169491525423729	118	992	1244,4846	ABCC2,NOS3
SMP00496	Galactosemia III	0.63831198968564	-0.448928103118314	8	1	0.00847457627118644	118	992	7358	UGDH
SMP00495	Galactosemia II (GALK)	0.63831198968564	-0.448928103118314	8	1	0.00847457627118644	118	992	7358	UGDH
SMP00010	Nucleotide Sugars Metabolism	0.63831198968564	-0.448928103118314	8	1	0.00847457627118644	118	992	7358	UGDH
SMP00127	Glucose-Alanine Cycle	0.63831198968564	-0.448928103118314	8	1	0.00847457627118644	118	992	84706	GPT2
SMP00123	Betaine Metabolism	0.63831198968564	-0.448928103118314	8	1	0.00847457627118644	118	992	10400	PEMT
SMP00691	Nalbuphine Action Pathway	0.641832470788071	-0.44342795827351	27	3	0.0254237288135593	118	992	481,6324,478	ATP1B1,SCN1B,ATP1A3
SMP00423	Desipramine Action Pathway	0.641832470788071	-0.44342795827351	27	3	0.0254237288135593	118	992	481,6324,478	ATP1B1,SCN1B,ATP1A3
SMP00725	Fructose intolerance- hereditary	0.65148761545197	-0.428496891881155	18	2	0.0169491525423729	118	992	3098,226	HK1,ALDOA
SMP00649	Lamivudine Metabolism Pathway	0.65148761545197	-0.428496891881155	18	2	0.0169491525423729	118	992	1244,10257	ABCC2,ABCC4
SMP00561	Fructosuria	0.65148761545197	-0.428496891881155	18	2	0.0169491525423729	118	992	3098,226	HK1,ALDOA
SMP00064	Fructose and Mannose Degradation	0.65148761545197	-0.428496891881155	18	2	0.0169491525423729	118	992	3098,226	HK1,ALDOA
SMP00706	Tenoxicam Action Pathway	0.667058321638749	-0.404877798150302	28	3	0.0254237288135593	118	992	113612,9536,1573	CYP2U1,PTGES,CYP2J2
SMP00693	Antrafenine Action Pathway	0.667058321638749	-0.404877798150302	28	3	0.0254237288135593	118	992	113612,9536,1573	CYP2U1,PTGES,CYP2J2
SMP00102	Bromfenac Action Pathway	0.667058321638749	-0.404877798150302	28	3	0.0254237288135593	118	992	113612,9536,1573	CYP2U1,PTGES,CYP2J2
SMP00699	Lumiracoxib Action Pathway	0.667058321638749	-0.404877798150302	28	3	0.0254237288135593	118	992	113612,9536,1573	CYP2U1,PTGES,CYP2J2
SMP00098	Ketorolac Action Pathway	0.667058321638749	-0.404877798150302	28	3	0.0254237288135593	118	992	113612,9536,1573	CYP2U1,PTGES,CYP2J2
SMP00106	Meloxicam Action Pathway	0.667058321638749	-0.404877798150302	28	3	0.0254237288135593	118	992	113612,9536,1573	CYP2U1,PTGES,CYP2J2
SMP00707	Salsalate Action Pathway	0.667058321638749	-0.404877798150302	28	3	0.0254237288135593	118	992	113612,9536,1573	CYP2U1,PTGES,CYP2J2
SMP00085	Ketoprofen Action Pathway	0.667058321638749	-0.404877798150302	28	3	0.0254237288135593	118	992	113612,9536,1573	CYP2U1,PTGES,CYP2J2
SMP00692	Antipyrine Action Pathway	0.667058321638749	-0.404877798150302	28	3	0.0254237288135593	118	992	113612,9536,1573	CYP2U1,PTGES,CYP2J2
SMP00353	Leukotriene C4 Synthesis Deficiency	0.667058321638749	-0.404877798150302	28	3	0.0254237288135593	118	992	113612,9536,1573	CYP2U1,PTGES,CYP2J2
SMP00700	Lornoxicam Action Pathway	0.667058321638749	-0.404877798150302	28	3	0.0254237288135593	118	992	113612,9536,1573	CYP2U1,PTGES,CYP2J2
SMP00701	Phenylbutazone Action Pathway	0.667058321638749	-0.404877798150302	28	3	0.0254237288135593	118	992	113612,9536,1573	CYP2U1,PTGES,CYP2J2
SMP00398	Lidocaine (Local Anaesthetic) Action Pathway	0.667058321638749	-0.404877798150302	28	3	0.0254237288135593	118	992	481,6324,478	ATP1B1,SCN1B,ATP1A3
SMP00094	Sulindac Action Pathway	0.667058321638749	-0.404877798150302	28	3	0.0254237288135593	118	992	113612,9536,1573	CYP2U1,PTGES,CYP2J2
SMP00114	Nabumetone Action Pathway	0.667058321638749	-0.404877798150302	28	3	0.0254237288135593	118	992	113612,9536,1573	CYP2U1,PTGES,CYP2J2
SMP00109	Mefenamic Acid Action Pathway	0.667058321638749	-0.404877798150302	28	3	0.0254237288135593	118	992	113612,9536,1573	CYP2U1,PTGES,CYP2J2
SMP00113	Oxaprozin Action Pathway	0.667058321638749	-0.404877798150302	28	3	0.0254237288135593	118	992	113612,9536,1573	CYP2U1,PTGES,CYP2J2
SMP00702	Nepafenac Action Pathway	0.667058321638749	-0.404877798150302	28	3	0.0254237288135593	118	992	113612,9536,1573	CYP2U1,PTGES,CYP2J2
SMP00698	Magnesium salicylate Action Pathway	0.667058321638749	-0.404877798150302	28	3	0.0254237288135593	118	992	113612,9536,1573	CYP2U1,PTGES,CYP2J2
SMP00289	Diflunisal Action Pathway	0.667058321638749	-0.404877798150302	28	3	0.0254237288135593	118	992	113612,9536,1573	CYP2U1,PTGES,CYP2J2
SMP00708	Salicylate-sodium Action Pathway	0.667058321638749	-0.404877798150302	28	3	0.0254237288135593	118	992	113612,9536,1573	CYP2U1,PTGES,CYP2J2
SMP00077	Piroxicam Action Pathway	0.667058321638749	-0.404877798150302	28	3	0.0254237288135593	118	992	113612,9536,1573	CYP2U1,PTGES,CYP2J2
SMP00083	Acetylsalicylic Acid Action Pathway	0.667058321638749	-0.404877798150302	28	3	0.0254237288135593	118	992	113612,9536,1573	CYP2U1,PTGES,CYP2J2
SMP00710	Acetaminophen  Action Pathway	0.667058321638749	-0.404877798150302	28	3	0.0254237288135593	118	992	113612,9536,1573	CYP2U1,PTGES,CYP2J2
SMP00697	Flurbiprofen Action Pathway	0.667058321638749	-0.404877798150302	28	3	0.0254237288135593	118	992	113612,9536,1573	CYP2U1,PTGES,CYP2J2
SMP00084	Etodolac Action Pathway	0.667058321638749	-0.404877798150302	28	3	0.0254237288135593	118	992	113612,9536,1573	CYP2U1,PTGES,CYP2J2
SMP00075	Arachidonic Acid Metabolism	0.667058321638749	-0.404877798150302	28	3	0.0254237288135593	118	992	113612,9536,1573	CYP2U1,PTGES,CYP2J2
SMP00696	Fenoprofen Action Pathway	0.667058321638749	-0.404877798150302	28	3	0.0254237288135593	118	992	113612,9536,1573	CYP2U1,PTGES,CYP2J2
SMP00703	Trisalicylate-choline Action Pathway	0.667058321638749	-0.404877798150302	28	3	0.0254237288135593	118	992	113612,9536,1573	CYP2U1,PTGES,CYP2J2
SMP00709	Salicylic Acid Action Pathway	0.667058321638749	-0.404877798150302	28	3	0.0254237288135593	118	992	113612,9536,1573	CYP2U1,PTGES,CYP2J2
SMP00093	Diclofenac Action Pathway	0.667058321638749	-0.404877798150302	28	3	0.0254237288135593	118	992	113612,9536,1573	CYP2U1,PTGES,CYP2J2
SMP00695	Etoricoxib Action Pathway	0.667058321638749	-0.404877798150302	28	3	0.0254237288135593	118	992	113612,9536,1573	CYP2U1,PTGES,CYP2J2
SMP00101	Suprofen Action Pathway	0.667058321638749	-0.404877798150302	28	3	0.0254237288135593	118	992	113612,9536,1573	CYP2U1,PTGES,CYP2J2
SMP00704	Tolmetin Action Pathway	0.667058321638749	-0.404877798150302	28	3	0.0254237288135593	118	992	113612,9536,1573	CYP2U1,PTGES,CYP2J2
SMP00694	Carprofen Action Pathway	0.667058321638749	-0.404877798150302	28	3	0.0254237288135593	118	992	113612,9536,1573	CYP2U1,PTGES,CYP2J2
SMP00705	Tiaprofenic Acid Action Pathway	0.667058321638749	-0.404877798150302	28	3	0.0254237288135593	118	992	113612,9536,1573	CYP2U1,PTGES,CYP2J2
SMP00087	Rofecoxib Action Pathway	0.667058321638749	-0.404877798150302	28	3	0.0254237288135593	118	992	113612,9536,1573	CYP2U1,PTGES,CYP2J2
SMP00116	Valdecoxib Action Pathway	0.667058321638749	-0.404877798150302	28	3	0.0254237288135593	118	992	113612,9536,1573	CYP2U1,PTGES,CYP2J2
SMP00120	Naproxen Action Pathway	0.667058321638749	-0.404877798150302	28	3	0.0254237288135593	118	992	113612,9536,1573	CYP2U1,PTGES,CYP2J2
SMP00228	Pantoprazole Action Pathway	0.681685145395698	-0.383187391380816	9	1	0.00847457627118644	118	992	1131	CHRM3
SMP00232	Cimetidine Action Pathway	0.681685145395698	-0.383187391380816	9	1	0.00847457627118644	118	992	1131	CHRM3
SMP00225	Esomeprazole Action Pathway	0.681685145395698	-0.383187391380816	9	1	0.00847457627118644	118	992	1131	CHRM3
SMP00230	Ranitidine Action Pathway	0.681685145395698	-0.383187391380816	9	1	0.00847457627118644	118	992	1131	CHRM3
SMP00734	Roxatidine acetate Action Pathway	0.681685145395698	-0.383187391380816	9	1	0.00847457627118644	118	992	1131	CHRM3
SMP00226	Omeprazole Action Pathway	0.681685145395698	-0.383187391380816	9	1	0.00847457627118644	118	992	1131	CHRM3
SMP00735	Metiamide Action Pathway	0.681685145395698	-0.383187391380816	9	1	0.00847457627118644	118	992	1131	CHRM3
SMP00736	Betazole Action Pathway	0.681685145395698	-0.383187391380816	9	1	0.00847457627118644	118	992	1131	CHRM3
SMP00589	Gastric Acid Production	0.681685145395698	-0.383187391380816	9	1	0.00847457627118644	118	992	1131	CHRM3
SMP00229	Rabeprazole Action Pathway	0.681685145395698	-0.383187391380816	9	1	0.00847457627118644	118	992	1131	CHRM3
SMP00233	Nizatidine Action Pathway	0.681685145395698	-0.383187391380816	9	1	0.00847457627118644	118	992	1131	CHRM3
SMP00227	Lansoprazole Action Pathway	0.681685145395698	-0.383187391380816	9	1	0.00847457627118644	118	992	1131	CHRM3
SMP00231	Famotidine Action Pathway	0.681685145395698	-0.383187391380816	9	1	0.00847457627118644	118	992	1131	CHRM3
SMP00246	Pirenzepine Action Pathway	0.681685145395698	-0.383187391380816	9	1	0.00847457627118644	118	992	1131	CHRM3
SMP00405	Codeine Action Pathway	0.690983829395841	-0.369638857230925	29	3	0.0254237288135593	118	992	481,6324,478	ATP1B1,SCN1B,ATP1A3
SMP00104	Indomethacin Action Pathway	0.690983829395841	-0.369638857230925	29	3	0.0254237288135593	118	992	113612,9536,1573	CYP2U1,PTGES,CYP2J2
SMP00363	Ornithine Aminotransferase Deficiency (OAT Deficiency)	0.709048898147996	-0.343830787059493	20	2	0.0169491525423729	118	992	445,2628	ASS1,GATM
SMP00506	Hyperornithinemia-hyperammonemia-homocitrullinuria [HHH-syndrome]	0.709048898147996	-0.343830787059493	20	2	0.0169491525423729	118	992	445,2628	ASS1,GATM
SMP00507	L-arginine:glycine amidinotransferase deficiency	0.709048898147996	-0.343830787059493	20	2	0.0169491525423729	118	992	445,2628	ASS1,GATM
SMP00505	Hyperornithinemia with gyrate atrophy (HOGA)	0.709048898147996	-0.343830787059493	20	2	0.0169491525423729	118	992	445,2628	ASS1,GATM
SMP00362	Arginine: Glycine Amidinotransferase Deficiency (AGAT Deficiency)	0.709048898147996	-0.343830787059493	20	2	0.0169491525423729	118	992	445,2628	ASS1,GATM
SMP00504	Creatine deficiency- guanidinoacetate methyltransferase deficiency	0.709048898147996	-0.343830787059493	20	2	0.0169491525423729	118	992	445,2628	ASS1,GATM
SMP00207	Prolidase Deficiency (PD)	0.709048898147996	-0.343830787059493	20	2	0.0169491525423729	118	992	445,2628	ASS1,GATM
SMP00360	Hyperprolinemia Type II	0.709048898147996	-0.343830787059493	20	2	0.0169491525423729	118	992	445,2628	ASS1,GATM
SMP00188	Guanidinoacetate Methyltransferase Deficiency (GAMT Deficiency)	0.709048898147996	-0.343830787059493	20	2	0.0169491525423729	118	992	445,2628	ASS1,GATM
SMP00208	Prolinemia Type II	0.709048898147996	-0.343830787059493	20	2	0.0169491525423729	118	992	445,2628	ASS1,GATM
SMP00361	Hyperprolinemia Type I	0.709048898147996	-0.343830787059493	20	2	0.0169491525423729	118	992	445,2628	ASS1,GATM
SMP00020	Arginine and Proline Metabolism	0.709048898147996	-0.343830787059493	20	2	0.0169491525423729	118	992	445,2628	ASS1,GATM
SMP00422	Imipramine Action Pathway	0.713612808542283	-0.337414748687003	30	3	0.0254237288135593	118	992	481,6324,478	ATP1B1,SCN1B,ATP1A3
SMP00482	Mitochondrial Beta-Oxidation of Long Chain Saturated Fatty Acids	0.7198958807417	-0.328648687510054	10	1	0.00847457627118644	118	992	2180	ACSL1
SMP00437	Vincristine Action Pathway	0.7198958807417	-0.328648687510054	10	1	0.00847457627118644	118	992	1244	ABCC2
SMP00438	Vindesine Action Pathway	0.7198958807417	-0.328648687510054	10	1	0.00847457627118644	118	992	1244	ABCC2
SMP00060	Pyruvate Metabolism	0.734757036520486	-0.308215396974308	21	2	0.0169491525423729	118	992	217,197257	ALDH2,LDHD
SMP00334	Pyruvate Decarboxylase E1 Component Deficiency (PDHE1 Deficiency)	0.734757036520486	-0.308215396974308	21	2	0.0169491525423729	118	992	217,197257	ALDH2,LDHD
SMP00525	Fabry disease	0.734757036520486	-0.308215396974308	21	2	0.0169491525423729	118	992	7368,9331	UGT8,B4GALT6
SMP00526	Krabbe disease	0.734757036520486	-0.308215396974308	21	2	0.0169491525423729	118	992	7368,9331	UGT8,B4GALT6
SMP00349	Gaucher Disease	0.734757036520486	-0.308215396974308	21	2	0.0169491525423729	118	992	7368,9331	UGT8,B4GALT6
SMP00196	Leigh Syndrome	0.734757036520486	-0.308215396974308	21	2	0.0169491525423729	118	992	217,197257	ALDH2,LDHD
SMP00433	Irinotecan Action Pathway	0.734757036520486	-0.308215396974308	21	2	0.0169491525423729	118	992	1244,590	ABCC2,BCHE
SMP00600	Irinotecan Metabolism Pathway	0.734757036520486	-0.308215396974308	21	2	0.0169491525423729	118	992	1244,590	ABCC2,BCHE
SMP00034	Sphingolipid Metabolism	0.734757036520486	-0.308215396974308	21	2	0.0169491525423729	118	992	7368,9331	UGT8,B4GALT6
SMP00212	Pyruvate Dehydrogenase Complex Deficiency	0.734757036520486	-0.308215396974308	21	2	0.0169491525423729	118	992	217,197257	ALDH2,LDHD
SMP00347	Metachromatic Leukodystrophy (MLD)	0.734757036520486	-0.308215396974308	21	2	0.0169491525423729	118	992	7368,9331	UGT8,B4GALT6
SMP00348	Globoid Cell Leukodystrophy	0.734757036520486	-0.308215396974308	21	2	0.0169491525423729	118	992	7368,9331	UGT8,B4GALT6
SMP00558	Primary hyperoxaluria II- PH2	0.734757036520486	-0.308215396974308	21	2	0.0169491525423729	118	992	217,197257	ALDH2,LDHD
SMP00559	Pyruvate kinase deficiency	0.734757036520486	-0.308215396974308	21	2	0.0169491525423729	118	992	217,197257	ALDH2,LDHD
SMP00426	Fluoxetine Action Pathway	0.734959792506173	-0.307939485338857	31	3	0.0254237288135593	118	992	481,6324,478	ATP1B1,SCN1B,ATP1A3
SMP00436	Vinblastine Action Pathway	0.753554013200997	-0.282954580404408	11	1	0.00847457627118644	118	992	1244	ABCC2
SMP00635	Valproic Acid Metabolism Pathway	0.753554013200997	-0.282954580404408	11	1	0.00847457627118644	118	992	1962	EHHADH
SMP00439	Vinorelbine Action Pathway	0.753554013200997	-0.282954580404408	11	1	0.00847457627118644	118	992	1244	ABCC2
SMP00431	Nicotine Action Pathway	0.755048277974093	-0.280973587440918	32	3	0.0254237288135593	118	992	481,6324,478	ATP1B1,SCN1B,ATP1A3
SMP00408	Methadone Action Pathway	0.755048277974093	-0.280973587440918	32	3	0.0254237288135593	118	992	481,6324,478	ATP1B1,SCN1B,ATP1A3
SMP00219	UMP Synthase Deiciency (Orotic Aciduria)	0.780448628058315	-0.247886360464692	23	2	0.0169491525423729	118	992	1890,129607	TYMP,CMPK2
SMP00202	MNGIE (Mitochondrial Neurogastrointestinal Encephalopathy)	0.780448628058315	-0.247886360464692	23	2	0.0169491525423729	118	992	1890,129607	TYMP,CMPK2
SMP00172	Beta Ureidopropionase Deficiency	0.780448628058315	-0.247886360464692	23	2	0.0169491525423729	118	992	1890,129607	TYMP,CMPK2
SMP00046	Pyrimidine Metabolism	0.780448628058315	-0.247886360464692	23	2	0.0169491525423729	118	992	1890,129607	TYMP,CMPK2
SMP00178	Dihydropyrimidinase Deficiency	0.780448628058315	-0.247886360464692	23	2	0.0169491525423729	118	992	1890,129607	TYMP,CMPK2
SMP00543	Methylenetetrahydrofolate Reductase Deficiency (MTHFRD)	0.78319787298068	-0.244369903575602	12	1	0.00847457627118644	118	992	10840	ALDH1L1
SMP00053	Folate Metabolism	0.78319787298068	-0.244369903575602	12	1	0.00847457627118644	118	992	10840	ALDH1L1
SMP00432	Methotrexate Action Pathway	0.78319787298068	-0.244369903575602	12	1	0.00847457627118644	118	992	10840	ALDH1L1
SMP00724	Folate malabsorption- hereditary	0.78319787298068	-0.244369903575602	12	1	0.00847457627118644	118	992	10840	ALDH1L1
SMP00096	Celecoxib Action Pathway	0.791579171639396	-0.233725377323742	34	3	0.0254237288135593	118	992	113612,9536,1573	CYP2U1,PTGES,CYP2J2
SMP00429	Disulfiram Action Pathway	0.800624241322407	-0.22236355393826	24	2	0.0169491525423729	118	992	4128,217	MAOA,ALDH2
SMP00043	Galactose Metabolism	0.809302618889482	-0.211582366492287	13	1	0.00847457627118644	118	992	3098	HK1
SMP00182	Galactosemia	0.809302618889482	-0.211582366492287	13	1	0.00847457627118644	118	992	3098	HK1
SMP00282	Streptokinase Action Pathway	0.832287594347404	-0.183577231606817	14	1	0.00847457627118644	118	992	2161	F12
SMP00185	Glutaric Aciduria Type I	0.832287594347404	-0.183577231606817	14	1	0.00847457627118644	118	992	2180	ACSL1
SMP00268	Warfarin Action Pathway	0.832287594347404	-0.183577231606817	14	1	0.00847457627118644	118	992	2161	F12
SMP00276	Argatroban Action Pathway	0.832287594347404	-0.183577231606817	14	1	0.00847457627118644	118	992	2161	F12
SMP00288	Aprotinin Action Pathway	0.832287594347404	-0.183577231606817	14	1	0.00847457627118644	118	992	2161	F12
SMP00540	Very-long-chain acyl coa dehydrogenase deficiency (VLCAD)	0.832287594347404	-0.183577231606817	14	1	0.00847457627118644	118	992	2180	ACSL1
SMP00279	Ximelagatran Action Pathway	0.832287594347404	-0.183577231606817	14	1	0.00847457627118644	118	992	2161	F12
SMP00281	Anistreplase Action Pathway	0.832287594347404	-0.183577231606817	14	1	0.00847457627118644	118	992	2161	F12
SMP00545	Trifunctional protein deficiency	0.832287594347404	-0.183577231606817	14	1	0.00847457627118644	118	992	2180	ACSL1
SMP00656	Dicoumarol Action Pathway	0.832287594347404	-0.183577231606817	14	1	0.00847457627118644	118	992	2161	F12
SMP00283	Tenecteplase Action Pathway	0.832287594347404	-0.183577231606817	14	1	0.00847457627118644	118	992	2161	F12
SMP00542	Medium chain acyl-coa dehydrogenase deficiency (MCAD)	0.832287594347404	-0.183577231606817	14	1	0.00847457627118644	118	992	2180	ACSL1
SMP00269	Acenocoumarol Action Pathway	0.832287594347404	-0.183577231606817	14	1	0.00847457627118644	118	992	2161	F12
SMP00280	Alteplase Action Pathway	0.832287594347404	-0.183577231606817	14	1	0.00847457627118644	118	992	2161	F12
SMP00198	Malonic Aciduria	0.832287594347404	-0.183577231606817	14	1	0.00847457627118644	118	992	18	ABAT
SMP00277	Bivalirudin Action Pathway	0.832287594347404	-0.183577231606817	14	1	0.00847457627118644	118	992	2161	F12
SMP00271	Phenprocoumon Action Pathway	0.832287594347404	-0.183577231606817	14	1	0.00847457627118644	118	992	2161	F12
SMP00201	Methylmalonic Aciduria Due to Cobalamin-Related Disorders	0.832287594347404	-0.183577231606817	14	1	0.00847457627118644	118	992	18	ABAT
SMP00235	Short Chain Acyl CoA Dehydrogenase Deficiency (SCAD Deficiency)	0.832287594347404	-0.183577231606817	14	1	0.00847457627118644	118	992	2180	ACSL1
SMP00285	Reteplase Action Pathway	0.832287594347404	-0.183577231606817	14	1	0.00847457627118644	118	992	2161	F12
SMP00278	Lepirudin Action Pathway	0.832287594347404	-0.183577231606817	14	1	0.00847457627118644	118	992	2161	F12
SMP00181	Ethylmalonic Encephalopathy	0.832287594347404	-0.183577231606817	14	1	0.00847457627118644	118	992	2180	ACSL1
SMP00655	Phenindione Action Pathway	0.832287594347404	-0.183577231606817	14	1	0.00847457627118644	118	992	2161	F12
SMP00586	Coagulation 	0.832287594347404	-0.183577231606817	14	1	0.00847457627118644	118	992	2161	F12
SMP00284	Urokinase Action Pathway	0.832287594347404	-0.183577231606817	14	1	0.00847457627118644	118	992	2161	F12
SMP00287	Tranexamic Acid Action Pathway	0.832287594347404	-0.183577231606817	14	1	0.00847457627118644	118	992	2161	F12
SMP00538	Carnitine palmitoyl transferase deficiency (I)	0.832287594347404	-0.183577231606817	14	1	0.00847457627118644	118	992	2180	ACSL1
SMP00270	Dicumarol Action Pathway	0.832287594347404	-0.183577231606817	14	1	0.00847457627118644	118	992	2161	F12
SMP00541	Carnitine palmitoyl transferase deficiency (II)	0.832287594347404	-0.183577231606817	14	1	0.00847457627118644	118	992	2180	ACSL1
SMP00502	Malonyl-coa decarboxylase deficiency	0.832287594347404	-0.183577231606817	14	1	0.00847457627118644	118	992	18	ABAT
SMP00051	Fatty acid Metabolism	0.832287594347404	-0.183577231606817	14	1	0.00847457627118644	118	992	2180	ACSL1
SMP00286	Aminocaproic Acid Action Pathway	0.832287594347404	-0.183577231606817	14	1	0.00847457627118644	118	992	2161	F12
SMP00016	Propanoate Metabolism	0.832287594347404	-0.183577231606817	14	1	0.00847457627118644	118	992	18	ABAT
SMP00539	Long chain acyl-CoA dehydrogenase deficiency (LCAD)	0.832287594347404	-0.183577231606817	14	1	0.00847457627118644	118	992	2180	ACSL1
SMP00025	Phospholipid Biosynthesis	0.836140788719543	-0.178958272517135	26	2	0.0169491525423729	118	992	10400,1040	PEMT,CDS1
SMP00275	Ardeparin Action Pathway	0.852522833478547	-0.159555286044096	15	1	0.00847457627118644	118	992	2161	F12
SMP00345	Congenital Erythropoietic Porphyria (CEP) or Gunther Disease	0.852522833478547	-0.159555286044096	15	1	0.00847457627118644	118	992	7390	UROS
SMP00518	Glucose-6-phosphate dehydrogenase deficiency	0.852522833478547	-0.159555286044096	15	1	0.00847457627118644	118	992	226	ALDOA
SMP00609	Mercaptopurine Metabolism Pathway	0.852522833478547	-0.159555286044096	15	1	0.00847457627118644	118	992	10257	ABCC4
SMP00031	Pentose Phosphate Pathway	0.852522833478547	-0.159555286044096	15	1	0.00847457627118644	118	992	226	ALDOA
SMP00273	Fondaparinux Action Pathway	0.852522833478547	-0.159555286044096	15	1	0.00847457627118644	118	992	2161	F12
SMP00344	Acute Intermittent Porphyria	0.852522833478547	-0.159555286044096	15	1	0.00847457627118644	118	992	7390	UROS
SMP00274	Heparin Action Pathway	0.852522833478547	-0.159555286044096	15	1	0.00847457627118644	118	992	2161	F12
SMP00024	Porphyrin Metabolism	0.852522833478547	-0.159555286044096	15	1	0.00847457627118644	118	992	7390	UROS
SMP00272	Enoxaparin Action Pathway	0.852522833478547	-0.159555286044096	15	1	0.00847457627118644	118	992	2161	F12
SMP00342	Hereditary Coproporphyria (HCP)	0.852522833478547	-0.159555286044096	15	1	0.00847457627118644	118	992	7390	UROS
SMP00519	Ribose-5-phosphate isomerase deficiency	0.852522833478547	-0.159555286044096	15	1	0.00847457627118644	118	992	226	ALDOA
SMP00346	Porphyria Variegata (PV)	0.852522833478547	-0.159555286044096	15	1	0.00847457627118644	118	992	7390	UROS
SMP00520	Transaldolase deficiency	0.852522833478547	-0.159555286044096	15	1	0.00847457627118644	118	992	226	ALDOA
SMP00652	Mycophenolic Acid Metabolism Pathway	0.870334814698992	-0.138877296885551	16	1	0.00847457627118644	118	992	1244	ABCC2
SMP00406	Morphine Action Pathway	0.875111716466403	-0.133403724812801	40	3	0.0254237288135593	118	992	481,6324,478	ATP1B1,SCN1B,ATP1A3
SMP00218	Tyrosinemia Type I	0.886011548171236	-0.121025294408685	17	1	0.00847457627118644	118	992	4128	MAOA
SMP00390	Tay-Sachs Disease	0.886011548171236	-0.121025294408685	17	1	0.00847457627118644	118	992	3098	HK1
SMP00045	Amino Sugar Metabolism	0.886011548171236	-0.121025294408685	17	1	0.00847457627118644	118	992	3098	HK1
SMP00498	Dopamine beta-hydroxylase deficiency	0.886011548171236	-0.121025294408685	17	1	0.00847457627118644	118	992	4128	MAOA
SMP00533	Monoamine oxidase-a deficiency (MAO-A)	0.886011548171236	-0.121025294408685	17	1	0.00847457627118644	118	992	4128	MAOA
SMP00240	Salla Disease/Infantile Sialic Acid Storage Disease	0.886011548171236	-0.121025294408685	17	1	0.00847457627118644	118	992	3098	HK1
SMP00534	G(M2)-Gangliosidosis: Variant B- Tay-sachs disease	0.886011548171236	-0.121025294408685	17	1	0.00847457627118644	118	992	3098	HK1
SMP00190	Hawkinsinuria	0.886011548171236	-0.121025294408685	17	1	0.00847457627118644	118	992	4128	MAOA
SMP00006	Tyrosine Metabolism	0.886011548171236	-0.121025294408685	17	1	0.00847457627118644	118	992	4128	MAOA
SMP00216	Sialuria or French Type Sialuria	0.886011548171236	-0.121025294408685	17	1	0.00847457627118644	118	992	3098	HK1
SMP00217	Sialuria or French Type Sialuria	0.886011548171236	-0.121025294408685	17	1	0.00847457627118644	118	992	3098	HK1
SMP00169	Alkaptonuria	0.886011548171236	-0.121025294408685	17	1	0.00847457627118644	118	992	4128	MAOA
SMP00522	3-hydroxyisobutyric aciduria	0.890645554872445	-0.115808736636415	30	2	0.0169491525423729	118	992	217,18	ALDH2,ABAT
SMP00524	Isovaleric acidemia	0.890645554872445	-0.115808736636415	30	2	0.0169491525423729	118	992	217,18	ALDH2,ABAT
SMP00523	Isobutyryl-coa dehydrogenase deficiency	0.890645554872445	-0.115808736636415	30	2	0.0169491525423729	118	992	217,18	ALDH2,ABAT
SMP00237	3-Methylcrotonyl Coa Carboxylase Deficiency Type I	0.890645554872445	-0.115808736636415	30	2	0.0169491525423729	118	992	217,18	ALDH2,ABAT
SMP00238	Isovaleric Aciduria	0.890645554872445	-0.115808736636415	30	2	0.0169491525423729	118	992	217,18	ALDH2,ABAT
SMP00199	Maple Syrup Urine Disease	0.890645554872445	-0.115808736636415	30	2	0.0169491525423729	118	992	217,18	ALDH2,ABAT
SMP00521	3-hydroxyisobutyric acid dehydrogenase deficiency	0.890645554872445	-0.115808736636415	30	2	0.0169491525423729	118	992	217,18	ALDH2,ABAT
SMP00236	Propionic Acidemia	0.890645554872445	-0.115808736636415	30	2	0.0169491525423729	118	992	217,18	ALDH2,ABAT
SMP00200	Methylmalonic Aciduria	0.890645554872445	-0.115808736636415	30	2	0.0169491525423729	118	992	217,18	ALDH2,ABAT
SMP00384	Methylmalonate Semialdehyde Dehydrogenase Deficiency	0.890645554872445	-0.115808736636415	30	2	0.0169491525423729	118	992	217,18	ALDH2,ABAT
SMP00140	3-Methylglutaconic Aciduria Type III	0.890645554872445	-0.115808736636415	30	2	0.0169491525423729	118	992	217,18	ALDH2,ABAT
SMP00139	3-Methylglutaconic Aciduria Type I	0.890645554872445	-0.115808736636415	30	2	0.0169491525423729	118	992	217,18	ALDH2,ABAT
SMP00032	Valine- Leucine and Isoleucine Degradation	0.890645554872445	-0.115808736636415	30	2	0.0169491525423729	118	992	217,18	ALDH2,ABAT
SMP00173	Beta-Ketothiolase Deficiency	0.890645554872445	-0.115808736636415	30	2	0.0169491525423729	118	992	217,18	ALDH2,ABAT
SMP00141	3-Methylglutaconic Aciduria Type IV	0.890645554872445	-0.115808736636415	30	2	0.0169491525423729	118	992	217,18	ALDH2,ABAT
SMP00137	2-Methyl-3-Hydroxybutryl CoA Dehydrogenase Deficiency	0.890645554872445	-0.115808736636415	30	2	0.0169491525423729	118	992	217,18	ALDH2,ABAT
SMP00138	3-Hydroxy-3-Methylglutaryl-CoA Lyase Deficiency	0.890645554872445	-0.115808736636415	30	2	0.0169491525423729	118	992	217,18	ALDH2,ABAT
SMP00355	Mitochondrial Electron Transport Chain	0.911945436372132	-0.0921751192369328	19	1	0.00847457627118644	118	992	2597	GAPDH
SMP00086	Ibuprofen Action Pathway	0.93426085091199	-0.0679995961140267	47	3	0.0254237288135593	118	992	113612,9536,1573	CYP2U1,PTGES,CYP2J2
SMP00336	Vitamin A Deficiency	0.935285106511166	-0.0669038694242532	35	2	0.0169491525423729	118	992	9227,1592	LRAT,CYP26A1
SMP00074	Retinol Metabolism	0.935285106511166	-0.0669038694242532	35	2	0.0169491525423729	118	992	9227,1592	LRAT,CYP26A1
SMP02298	Glutaminolysis and Cancer	0.935285106511166	-0.0669038694242532	35	2	0.0169491525423729	118	992	6510,4609	SLC1A5,MYC
SMP00136	2-Hydroxyglutric Aciduria (D And L Form)	0.940279071583937	-0.0615785631158563	22	1	0.00847457627118644	118	992	18	ABAT
SMP00567	Succinic semialdehyde dehydrogenase deficiency	0.940279071583937	-0.0615785631158563	22	1	0.00847457627118644	118	992	18	ABAT
SMP00339	Hyperinsulinism-Hyperammonemia Syndrome	0.940279071583937	-0.0615785631158563	22	1	0.00847457627118644	118	992	18	ABAT
SMP00243	4-Hydroxybutyric Aciduria/Succinic Semialdehyde Dehydrogenase Deficiency	0.940279071583937	-0.0615785631158563	22	1	0.00847457627118644	118	992	18	ABAT
SMP00385	Homocarnosinosis	0.940279071583937	-0.0615785631158563	22	1	0.00847457627118644	118	992	18	ABAT
SMP00072	Glutamate Metabolism	0.940279071583937	-0.0615785631158563	22	1	0.00847457627118644	118	992	18	ABAT
SMP02291	The oncogenic action of 2-hydroxyglutarate	0.964483923843835	-0.0361621146406494	26	1	0.00847457627118644	118	992	48	ACO1
SMP02358	The oncogenic action of L-2-hydroxyglutarate in  Hydroxygluaricaciduria	0.972634725980671	-0.027746677371949	28	1	0.00847457627118644	118	992	48	ACO1
SMP00640	Acetaminophen Metabolism Pathway	0.972634725980671	-0.027746677371949	28	1	0.00847457627118644	118	992	10257	ABCC4
SMP02359	The oncogenic action of D-2-hydroxyglutarate in  Hydroxygluaricaciduria 	0.975984417202555	-0.0243086586774911	29	1	0.00847457627118644	118	992	48	ACO1
SMP02292	The oncogenic action of Succinate	0.978927136595031	-0.0212980655799028	30	1	0.00847457627118644	118	992	48	ACO1
SMP02295	The oncogenic action of Fumarate	0.978927136595031	-0.0212980655799028	30	1	0.00847457627118644	118	992	48	ACO1
SMP00612	Esomeprazole Metabolism Pathway	0.999999999996893	-3.10722281238185e-12	2	0	0	118	992
SMP00616	Rabeprazole Metabolism Pathway	0.999999999996893	-3.10722281238185e-12	2	0	0	118	992
SMP00613	Omeprazole Metabolism Pathway	0.999999999996893	-3.10722281238185e-12	2	0	0	118	992
SMP00614	Lansoprazole Metabolism Pathway	0.999999999996893	-3.10722281238185e-12	2	0	0	118	992
SMP00615	Pantoprazole Metabolism Pathway	0.999999999996893	-3.10722281238185e-12	2	0	0	118	992
SMP00420	Bevacizumab Action Pathway	0.999999999999235	-7.64813126025166e-13	3	0	0	118	992
SMP00653	Rosiglitazone Metabolism Pathway	0.999999999999235	-7.64813126025166e-13	3	0	0	118	992
SMP00126	Phenylacetate Metabolism	0.999999999999235	-7.64813126025166e-13	3	0	0	118	992
SMP00564	Multiple carboxylase deficiency- neonatal or early onset form	0.999999999999235	-7.64813126025166e-13	3	0	0	118	992
SMP00619	Felodipine Metabolism Pathway	0.999999999999235	-7.64813126025166e-13	3	0	0	118	992
SMP00464	Vitamin K Metabolism	0.999999999999235	-7.64813126025166e-13	3	0	0	118	992
SMP00626	Desipramine Metabolism Pathway	0.999999999999235	-7.64813126025166e-13	3	0	0	118	992
SMP00174	Biotinidase Deficiency	0.999999999999235	-7.64813126025166e-13	3	0	0	118	992
SMP00472	Erlotinib Action Pathway	0.999999999999235	-7.64813126025166e-13	3	0	0	118	992
SMP00066	Biotin Metabolism	0.999999999999235	-7.64813126025166e-13	3	0	0	118	992
SMP00153	Quinapril Action Pathway	0.999999999999601	-3.99377145937629e-13	4	0	0	118	992
SMP00165	Valsartan Action Pathway	0.999999999999601	-3.99377145937629e-13	4	0	0	118	992
SMP00602	Teniposide Metabolism Pathway	0.999999999999601	-3.99377145937629e-13	4	0	0	118	992
SMP00150	Lisinopril Action Pathway	0.999999999999601	-3.99377145937629e-13	4	0	0	118	992
SMP00633	Felbamate Metabolism Pathway	0.999999999999601	-3.99377145937629e-13	4	0	0	118	992
SMP00164	Telmisartan Action Pathway	0.999999999999601	-3.99377145937629e-13	4	0	0	118	992
SMP00651	Artemether Metabolism Pathway	0.999999999999601	-3.99377145937629e-13	4	0	0	118	992
SMP00170	Aromatic L-Aminoacid Decarboxylase Deficiency	0.999999999999601	-3.99377145937629e-13	4	0	0	118	992
SMP00145	Benazepril Action Pathway	0.999999999999601	-3.99377145937629e-13	4	0	0	118	992
SMP00443	Teniposide Action Pathway	0.999999999999601	-3.99377145937629e-13	4	0	0	118	992
SMP00733	Temocapril Action Pathway	0.999999999999601	-3.99377145937629e-13	4	0	0	118	992
SMP00621	Codeine Metabolism Pathway	0.999999999999601	-3.99377145937629e-13	4	0	0	118	992
SMP00152	Perindopril Action Pathway	0.999999999999601	-3.99377145937629e-13	4	0	0	118	992
SMP00012	Catecholamine Biosynthesis	0.999999999999601	-3.99377145937629e-13	4	0	0	118	992
SMP00149	Fosinopril Action Pathway	0.999999999999601	-3.99377145937629e-13	4	0	0	118	992
SMP00065	Ubiquinone Biosynthesis	0.999999999999601	-3.99377145937629e-13	4	0	0	118	992
SMP00163	Olmesartan Action Pathway	0.999999999999601	-3.99377145937629e-13	4	0	0	118	992
SMP00154	Ramipril Action Pathway	0.999999999999601	-3.99377145937629e-13	4	0	0	118	992
SMP00497	Tyrosine hydroxylase deficiency	0.999999999999601	-3.99377145937629e-13	4	0	0	118	992
SMP00479	Plasmalogen Synthesis	0.999999999999601	-3.99377145937629e-13	4	0	0	118	992
SMP00148	Enalapril Action Pathway	0.999999999999601	-3.99377145937629e-13	4	0	0	118	992
SMP00162	Losartan Action Pathway	0.999999999999601	-3.99377145937629e-13	4	0	0	118	992
SMP00155	Rescinnamine Action Pathway	0.999999999999601	-3.99377145937629e-13	4	0	0	118	992
SMP00161	Irbesartan Action Pathway	0.999999999999601	-3.99377145937629e-13	4	0	0	118	992
SMP00639	Clomipramine Metabolism Pathway	0.999999999999601	-3.99377145937629e-13	4	0	0	118	992
SMP00146	Captopril Action Pathway	0.999999999999601	-3.99377145937629e-13	4	0	0	118	992
SMP00160	Forasartan Action Pathway	0.999999999999601	-3.99377145937629e-13	4	0	0	118	992
SMP00129	Malate-Aspartate Shuttle	0.999999999999601	-3.99377145937629e-13	4	0	0	118	992
SMP00587	Angiotensin Metabolism	0.999999999999601	-3.99377145937629e-13	4	0	0	118	992
SMP00159	Eprosartan Action Pathway	0.999999999999601	-3.99377145937629e-13	4	0	0	118	992
SMP00147	Cilazapril Action Pathway	0.999999999999601	-3.99377145937629e-13	4	0	0	118	992
SMP00156	Spirapril Action Pathway	0.999999999999601	-3.99377145937629e-13	4	0	0	118	992
SMP00151	Moexipril Action Pathway	0.999999999999601	-3.99377145937629e-13	4	0	0	118	992
SMP00158	Candesartan Action Pathway	0.999999999999601	-3.99377145937629e-13	4	0	0	118	992
SMP00157	Trandolapril Action Pathway	0.999999999999601	-3.99377145937629e-13	4	0	0	118	992
SMP00631	Prednisone Metabolism Pathway	0.999999999999937	-6.32549568280183e-14	1	0	0	118	992
SMP00265	Abciximab Action Pathway	0.999999999999937	-6.32549568280183e-14	1	0	0	118	992
SMP00476	Trastuzumab Action Pathway	0.999999999999937	-6.32549568280183e-14	1	0	0	118	992
SMP00593	Enalapril Metabolism Pathway	0.999999999999937	-6.32549568280183e-14	1	0	0	118	992
SMP00732	Temocapril Metabolism Pathway	0.999999999999937	-6.32549568280183e-14	1	0	0	118	992
SMP00632	Prednisolone Metabolism Pathway	0.999999999999937	-6.32549568280183e-14	1	0	0	118	992
SMP00473	Gefitinib Action Pathway	0.999999999999937	-6.32549568280183e-14	1	0	0	118	992
SMP00261	Ticlopidine Action Pathway	0.999999999999937	-6.32549568280183e-14	1	0	0	118	992
SMP00595	Moexipril Metabolism Pathway	0.999999999999937	-6.32549568280183e-14	1	0	0	118	992
SMP00475	Panitumumab Action Pathway	0.999999999999937	-6.32549568280183e-14	1	0	0	118	992
SMP00647	Thioguanine Metabolism Pathway	0.999999999999937	-6.32549568280183e-14	1	0	0	118	992
SMP00474	Cetuximab Action Pathway	0.999999999999937	-6.32549568280183e-14	1	0	0	118	992
SMP00591	Benazepril Metabolism Pathway	0.999999999999937	-6.32549568280183e-14	1	0	0	118	992
SMP00597	Ramipril Metabolism Pathway	0.999999999999937	-6.32549568280183e-14	1	0	0	118	992
SMP00267	Tirofiban Action Pathway	0.999999999999937	-6.32549568280183e-14	1	0	0	118	992
SMP00596	Quinapril Metabolism Pathway	0.999999999999937	-6.32549568280183e-14	1	0	0	118	992
SMP00617	Cimetidine Metabolism Pathway	0.999999999999937	-6.32549568280183e-14	1	0	0	118	992
SMP00421	Vatalanib Action Pathway	0.999999999999937	-6.32549568280183e-14	1	0	0	118	992
SMP00592	Cilazapril Metabolism Pathway	0.999999999999937	-6.32549568280183e-14	1	0	0	118	992
SMP00036	D-Arginine and D-Ornithine Metabolism	0.999999999999937	-6.32549568280183e-14	1	0	0	118	992
SMP00470	Fluorouracil Action Pathway	0.999999999999937	-6.32549568280183e-14	1	0	0	118	992
SMP00611	Ticlopidine Metabolism Pathway	0.999999999999937	-6.32549568280183e-14	1	0	0	118	992
SMP00599	Trandolapril Metabolism Pathway	0.999999999999937	-6.32549568280183e-14	1	0	0	118	992
SMP00594	Fosinopril Metabolism Pathway	0.999999999999937	-6.32549568280183e-14	1	0	0	118	992
SMP00598	Spirapril Metabolism Pathway	0.999999999999937	-6.32549568280183e-14	1	0	0	118	992
SMP00440	Prednisone Action Pathway	0.999999999999937	-6.32549568280183e-14	1	0	0	118	992
SMP00638	Levomethadyl Acetate Metabolism Pathway	0.999999999999937	-6.32549568280183e-14	1	0	0	118	992
SMP00441	Prednisolone Action Pathway	0.999999999999937	-6.32549568280183e-14	1	0	0	118	992
SMP00266	Eptifibatide Action Pathway	0.999999999999937	-6.32549568280183e-14	1	0	0	118	992
SMP00608	Fluorouracil Metabolism Pathway	0.999999999999937	-6.32549568280183e-14	1	0	0	118	992
SMP00468	Degradation of Superoxides	1.00000000000096	9.56734037561293e-13	5	0	0	118	992
SMP00021	Taurine and Hypotaurine Metabolism	1.00000000000096	9.56734037561293e-13	5	0	0	118	992
SMP00454	Repaglinide Action Pathway	1.00000000000096	9.56734037561293e-13	5	0	0	118	992
SMP00641	Doxepin Metabolism Pathway	1.00000000000096	9.56734037561293e-13	5	0	0	118	992
SMP00453	Nateglinide Action Pathway	1.00000000000096	9.56734037561293e-13	5	0	0	118	992
SMP00460	Glibenclamide Action Pathway	1.00000000000096	9.56734037561293e-13	5	0	0	118	992
SMP00643	Pancreas Function	1.00000000000096	9.56734037561293e-13	5	0	0	118	992
SMP00503	Hypophosphatasia	1.00000000000096	9.56734037561293e-13	5	0	0	118	992
SMP00017	Vitamin B6 Metabolism	1.00000000000096	9.56734037561293e-13	5	0	0	118	992
SMP00569	Succinyl CoA: 3-ketoacid CoA transferase deficiency	1.00000000000096	9.56734037561293e-13	5	0	0	118	992
SMP00071	Ketone Body Metabolism	1.00000000000096	9.56734037561293e-13	5	0	0	118	992
SMP00461	Gliclazide Action Pathway	1.00000000000096	9.56734037561293e-13	5	0	0	118	992
SMP00465	Carnitine Synthesis	1.00000000000096	9.56734037561293e-13	5	0	0	118	992
SMP00646	Fluoxetine Metabolism Pathway	1.00000000000193	1.9292511568191e-12	6	0	0	118	992
SMP00445	Spermidine and Spermine Biosynthesis	1.00000000000193	1.9292511568191e-12	6	0	0	118	992
SMP00478	Nucleotide Excision Repair 	1.00000000000193	1.9292511568191e-12	6	0	0	118	992
SMP00636	Venlafaxine Metabolism Pathway	1.00000000000193	1.9292511568191e-12	6	0	0	118	992
SMP00628	Nicotine Metabolism Pathway	1.00000000000193	1.9292511568191e-12	6	0	0	118	992
SMP00625	Imipramine Metabolism Pathway	1.00000000000193	1.9292511568191e-12	6	0	0	118	992
SMP00054	Fatty Acid Elongation In Mitochondria	1.00000000000353	3.52891431900755e-12	7	0	0	118	992
SMP00634	Carbamazepine Metabolism Pathway	1.00000000000353	3.52891431900755e-12	7	0	0	118	992
SMP00544	Long-chain-3-hydroxyacyl-coa dehydrogenase deficiency (LCHAD)	1.00000000000353	3.52891431900755e-12	7	0	0	118	992
SMP00041	Sulfate/Sulfite Metabolism	1.00000000000353	3.52891431900755e-12	7	0	0	118	992
SMP00532	Sulfite oxidase deficiency	1.00000000000353	3.52891431900755e-12	7	0	0	118	992
SMP00487	Hyperphenylalaniemia due to guanosine triphosphate cyclohydrolase deficiency	1.00000000000442	4.41811220739302e-12	8	0	0	118	992
SMP00005	Pterine Biosynthesis	1.00000000000442	4.41811220739302e-12	8	0	0	118	992
SMP00488	Hyperphenylalaninemia due to 6-pyruvoyltetrahydropterin synthase deficiency (ptps)	1.00000000000442	4.41811220739302e-12	8	0	0	118	992
SMP00605	Ifosfamide Metabolism Pathway	1.00000000000442	4.41811220739302e-12	8	0	0	118	992
SMP00481	Mitochondrial Beta-Oxidation of Medium Chain Saturated Fatty Acids	1.00000000000442	4.41811220739302e-12	8	0	0	118	992
SMP00028	Caffeine Metabolism	1.00000000000442	4.41811220739302e-12	8	0	0	118	992
SMP00073	Butyrate Metabolism	1.00000000000442	4.41811220739302e-12	8	0	0	118	992
SMP00480	Mitochondrial Beta-Oxidation of Short Chain Saturated Fatty Acids	1.00000000000442	4.41811220739302e-12	8	0	0	118	992
SMP00448	Ifosfamide Action Pathway	1.00000000000442	4.41811220739302e-12	8	0	0	118	992
SMP00490	Segawa syndrome	1.00000000000442	4.41811220739302e-12	8	0	0	118	992
SMP00568	Short-chain 3-hydroxyacyl-CoA dehydrogenase deficiency (SCHAD)	1.00000000000442	4.41811220739302e-12	8	0	0	118	992
SMP00491	Sepiapterin reductase deficiency	1.00000000000442	4.41811220739302e-12	8	0	0	118	992
SMP00486	Dopa-responsive dystonia	1.00000000000442	4.41811220739302e-12	8	0	0	118	992
SMP00489	Hyperphenylalaninemia due to dhpr-deficiency	1.00000000000442	4.41811220739302e-12	8	0	0	118	992
SMP00466	Transfer of Acetyl Groups into Mitochondria	1.00000000000442	4.41811220739302e-12	8	0	0	118	992
SMP00644	Celecoxib Metabolism Pathway	1.00000000000442	4.41811220739302e-12	8	0	0	118	992
SMP00642	Nevirapine Metabolism Pathway	1.00000000000442	4.41811220739302e-12	8	0	0	118	992
SMP00580	GLUT-1 deficiency syndrome	1.00000000000527	5.27239794988069e-12	9	0	0	118	992
SMP00444	Lactose Synthesis	1.00000000000527	5.27239794988069e-12	9	0	0	118	992
SMP00610	Clopidogrel Metabolism Pathway	1.00000000000527	5.27239794988069e-12	9	0	0	118	992
SMP00716	Thyroid hormone synthesis	1.00000000000527	5.27239794988069e-12	9	0	0	118	992
SMP00604	Cyclophosphamide Metabolism Pathway	1.00000000000527	5.27239794988069e-12	9	0	0	118	992
SMP00260	Clopidogrel Action Pathway	1.00000000000527	5.27239794988069e-12	9	0	0	118	992
SMP00452	Threonine and 2-Oxobutanoate Degradation	1.00000000000527	5.27239794988069e-12	9	0	0	118	992
SMP00579	Congenital disorder of glycosylation CDG-IId	1.00000000000527	5.27239794988069e-12	9	0	0	118	992
SMP00447	Cyclophosphamide Action Pathway	1.00000000000527	5.27239794988069e-12	9	0	0	118	992
SMP00606	Tamoxifen Metabolism Pathway	1.00000000000666	6.66283683663737e-12	10	0	0	118	992
SMP00471	Tamoxifen Action Pathway	1.00000000000666	6.66283683663737e-12	10	0	0	118	992
SMP00624	Methadone Metabolism Pathway	1.00000000000666	6.66283683663737e-12	10	0	0	118	992
SMP00566	17-alpha-hydroxylase deficiency (CYP17)	1.00000000000859	8.58889414112511e-12	11	0	0	118	992
SMP00371	Congenital Lipoid Adrenal Hyperplasia (CLAH) or Lipoid CAH	1.00000000000859	8.58889414112511e-12	11	0	0	118	992
SMP00575	11-beta-hydroxylase deficiency (CYP11B1)	1.00000000000859	8.58889414112511e-12	11	0	0	118	992
SMP00187	Glycerol Kinase Deficiency	1.00000000000859	8.58889414112511e-12	11	0	0	118	992
SMP00717	Apparent mineralocorticoid excess syndrome	1.00000000000859	8.58889414112511e-12	11	0	0	118	992
SMP00370	Tyrosinemia Type 3 (TYRO3)	1.00000000000859	8.58889414112511e-12	11	0	0	118	992
SMP00372	Adrenal Hyperplasia Type 5 or Congenital Adrenal Hyperplasia due to 17 Alpha-hydroxylase Deficiency	1.00000000000859	8.58889414112511e-12	11	0	0	118	992
SMP00391	Insulin Signalling	1.00000000000859	8.58889414112511e-12	11	0	0	118	992
SMP00008	Phenylalanine and Tyrosine Metabolism	1.00000000000859	8.58889414112511e-12	11	0	0	118	992
SMP00576	21-hydroxylase deficiency (CYP21)	1.00000000000859	8.58889414112511e-12	11	0	0	118	992
SMP00577	Corticosterone methyl oxidase I deficiency (CMO I)	1.00000000000859	8.58889414112511e-12	11	0	0	118	992
SMP00578	Corticosterone methyl oxidase II deficiency - CMO II	1.00000000000859	8.58889414112511e-12	11	0	0	118	992
SMP00206	Phenylketonuria	1.00000000000859	8.58889414112511e-12	11	0	0	118	992
SMP00530	Familial lipoprotein lipase deficiency	1.00000000000859	8.58889414112511e-12	11	0	0	118	992
SMP00529	D-glyceric acidura	1.00000000000859	8.58889414112511e-12	11	0	0	118	992
SMP00718	3-Beta-Hydroxysteroid Dehydrogenase Deficiency	1.00000000000859	8.58889414112511e-12	11	0	0	118	992
SMP00039	Glycerolipid Metabolism	1.00000000000859	8.58889414112511e-12	11	0	0	118	992
SMP00373	Adrenal Hyperplasia Type 3 or Congenital Adrenal Hyperplasia due to 21-hydroxylase Deficiency	1.00000000000859	8.58889414112511e-12	11	0	0	118	992
SMP00130	Steroidogenesis	1.00000000000859	8.58889414112511e-12	11	0	0	118	992
SMP00369	Tyrosinemia Type 2 (or Richner-Hanhart syndrome)	1.00000000000859	8.58889414112511e-12	11	0	0	118	992
SMP00494	Tyrosinemia- transient	1.00000000000892	8.91929954960284e-12	12	0	0	118	992
SMP00068	Androgen and Estrogen Metabolism	1.00000000000892	8.91929954960284e-12	12	0	0	118	992
SMP00565	Aromatase deficiency	1.00000000000892	8.91929954960284e-12	12	0	0	118	992
SMP00356	17-Beta Hydroxysteroid Dehydrogenase III Deficiency	1.00000000000892	8.91929954960284e-12	12	0	0	118	992
SMP02313	sarcosine oncometabolite pathway 	1.0000000000102	1.02042486782825e-11	13	0	0	118	992
SMP00603	Gemcitabine Metabolism Pathway	1.0000000000102	1.02042486782825e-11	13	0	0	118	992
SMP00446	Gemcitabine Action Pathway	1.0000000000102	1.02042486782825e-11	13	0	0	118	992
SMP00648	Sorafenib Metabolism Pathway	1.00000000001133	1.1328469730289e-11	14	0	0	118	992
SMP00622	Morphine Metabolism Pathway	1.00000000001348	1.34763473713656e-11	15	0	0	118	992
SMP00317	Familial Hypercholanemia (FHCA)	1.00000000001635	1.63549261007958e-11	17	0	0	118	992
SMP00316	Zellweger Syndrome	1.00000000001635	1.63549261007958e-11	17	0	0	118	992
SMP00315	Cerebrotendinous Xanthomatosis (CTX)	1.00000000001635	1.63549261007958e-11	17	0	0	118	992
SMP00314	Congenital Bile Acid Synthesis Defect Type II	1.00000000001635	1.63549261007958e-11	17	0	0	118	992
SMP00035	Bile Acid Biosynthesis	1.00000000001635	1.63549261007958e-11	17	0	0	118	992
SMP00318	Congenital Bile Acid Synthesis Defect Type III	1.00000000001635	1.63549261007958e-11	17	0	0	118	992
SMP00720	27-Hydroxylase Deficiency	1.00000000001635	1.63549261007958e-11	17	0	0	118	992
SMP00442	Etoposide Action Pathway	1.00000000001677	1.67706609490444e-11	18	0	0	118	992
SMP00601	Etoposide Metabolism Pathway	1.00000000001677	1.67706609490444e-11	18	0	0	118	992
SMP00548	Mitochondrial complex II deficiency	1.00000000001951	1.95141222879737e-11	20	0	0	118	992
SMP00057	Citric Acid Cycle	1.00000000001951	1.95141222879737e-11	20	0	0	118	992
SMP00551	Pyruvate dehydrogenase deficiency (E2)	1.00000000001951	1.95141222879737e-11	20	0	0	118	992
SMP00546	Congenital lactic acidosis	1.00000000001951	1.95141222879737e-11	20	0	0	118	992
SMP00549	2-ketoglutarate dehydrogenase complex deficiency	1.00000000001951	1.95141222879737e-11	20	0	0	118	992
SMP00547	Fumarase deficiency	1.00000000001951	1.95141222879737e-11	20	0	0	118	992
SMP00550	Pyruvate dehydrogenase deficiency (E3)	1.00000000001951	1.95141222879737e-11	20	0	0	118	992
SMP00590	Ibuprofen Metabolism Pathway	1.00000000002016	2.01578572521767e-11	22	0	0	118	992