TermID	Term	Enrichment	logP	Genes in Term	Target Genes in Term	Fraction of Targets in Term	Total Target Genes	Total Genes	Entrez Gene IDs	Gene Symbols
ko03040	Spliceosome	3.14907807370087e-13	-28.7864964739383	132	56	0.0487380330722367	1149	7161	9092,55119,51362,9984,10523,56949,6431,23451,9939,10713,1659,6634,5093,8559,10992,84991,56259,9775,6429,9343,8896,6434,9716,4670,27339,988,10772,23020,6628,10450,51639,51340,51691,9129,6430,10907,8175,6626,1665,3304,9416,6426,58517,8449,11157,27316,23350,10084,9128,1655,6428,6637,100534599,6625,10285,11325	SART1,PRPF38B,CDC40,THOC1,CHERP,XAB2,SRSF6,SF3B1,RBM8A,USP39,DHX8,SNRPD3,PCBP1,PRPF18,SF3B2,RBM17,CTNNBL1,EIF4A3,SRSF4,EFTUD2,BUD31,TRA2B,AQR,HNRNPM,PRPF19,CDC5L,SRSF10,SNRNP200,SNRPB,PPIE,SF3B6,CRNKL1,LSM8,PRPF3,SRSF5,TXNL4A,SF3A2,SNRPA,DHX15,HSPA1B,DDX23,SRSF1,RBM25,DHX16,LSM6,RBMX,U2SURP,PQBP1,PRPF4,DDX5,SRSF3,SNRPG,ISY1-RAB43,SNRNP70,SMNDC1,DDX42
hsa03040	Spliceosome	3.14907807370087e-13	-28.7864964739383	132	56	0.0487380330722367	1149	7161	9092,55119,51362,9984,10523,56949,6431,23451,9939,10713,1659,6634,5093,8559,10992,84991,56259,9775,6429,9343,8896,6434,9716,4670,27339,988,10772,23020,6628,10450,51639,51340,51691,9129,6430,10907,8175,6626,1665,3304,9416,6426,58517,8449,11157,27316,23350,10084,9128,1655,6428,6637,100534599,6625,10285,11325	SART1,PRPF38B,CDC40,THOC1,CHERP,XAB2,SRSF6,SF3B1,RBM8A,USP39,DHX8,SNRPD3,PCBP1,PRPF18,SF3B2,RBM17,CTNNBL1,EIF4A3,SRSF4,EFTUD2,BUD31,TRA2B,AQR,HNRNPM,PRPF19,CDC5L,SRSF10,SNRNP200,SNRPB,PPIE,SF3B6,CRNKL1,LSM8,PRPF3,SRSF5,TXNL4A,SF3A2,SNRPA,DHX15,HSPA1B,DDX23,SRSF1,RBM25,DHX16,LSM6,RBMX,U2SURP,PQBP1,PRPF4,DDX5,SRSF3,SNRPG,ISY1-RAB43,SNRNP70,SMNDC1,DDX42
hsa04141	Protein processing in endoplasmic reticulum	3.39276150103266e-10	-21.8042067380818	165	59	0.051348999129678	1149	7161	7323,10808,4287,80331,5589,23480,3300,7841,8454,3337,440275,29978,10134,55666,4121,5886,6745,824,6184,56681,1603,9632,6238,5887,55968,6185,596,3998,10130,6048,10113,578,56893,10952,9978,11253,30001,6746,27102,10277,3301,84447,55741,3304,79139,22872,54431,23640,9373,29927,1650,3703,6400,64374,22926,4217,55768,823,258010	UBE2D3,HSPH1,ATXN3,DNAJC5,PRKCSH,SEC61G,DNAJB2,MOGS,CUL1,DNAJB1,EIF2AK4,UBQLN2,BCAP31,NPLOC4,MAN1A1,RAD23A,SSR1,CAPN2,RPN1,SAR1A,DAD1,SEC24C,RRBP1,RAD23B,NSFL1C,RPN2,BCL2,LMAN1,PDIA6,RNF5,PREB,BAK1,UBQLN4,SEC61B,RBX1,MAN1B1,ERO1A,SSR2,EIF2AK1,UBE4B,DNAJA1,SYVN1,EDEM2,HSPA1B,DERL1,SEC31A,DNAJC10,HSPBP1,PLAA,SEC61A1,DDOST,STT3A,SEL1L,SIL1,ATF6,MAP3K5,NGLY1,CAPN1,SVIP
ko04141	Protein processing in endoplasmic reticulum	3.39276150103266e-10	-21.8042067380818	165	59	0.051348999129678	1149	7161	7323,10808,4287,80331,5589,23480,3300,7841,8454,3337,440275,29978,10134,55666,4121,5886,6745,824,6184,56681,1603,9632,6238,5887,55968,6185,596,3998,10130,6048,10113,578,56893,10952,9978,11253,30001,6746,27102,10277,3301,84447,55741,3304,79139,22872,54431,23640,9373,29927,1650,3703,6400,64374,22926,4217,55768,823,258010	UBE2D3,HSPH1,ATXN3,DNAJC5,PRKCSH,SEC61G,DNAJB2,MOGS,CUL1,DNAJB1,EIF2AK4,UBQLN2,BCAP31,NPLOC4,MAN1A1,RAD23A,SSR1,CAPN2,RPN1,SAR1A,DAD1,SEC24C,RRBP1,RAD23B,NSFL1C,RPN2,BCL2,LMAN1,PDIA6,RNF5,PREB,BAK1,UBQLN4,SEC61B,RBX1,MAN1B1,ERO1A,SSR2,EIF2AK1,UBE4B,DNAJA1,SYVN1,EDEM2,HSPA1B,DERL1,SEC31A,DNAJC10,HSPBP1,PLAA,SEC61A1,DDOST,STT3A,SEL1L,SIL1,ATF6,MAP3K5,NGLY1,CAPN1,SVIP
hsa04110	Cell cycle	7.30620671486595e-10	-21.0371267081179	124	48	0.0417754569190601	1149	7161	9232,10912,10926,8454,4998,891,10459,1031,5925,4193,5111,9126,890,4174,1027,51434,994,23595,7040,5347,9978,5591,1871,29882,990,9088,4171,8697,4087,8881,996,5933,1874,4616,7027,1869,7534,11200,7029,9133,1017,1870,7533,4089,9700,1029,3066,29945	PTTG1,GADD45G,DBF4,CUL1,ORC1,CCNB1,MAD2L2,CDKN2C,RB1,MDM2,PCNA,SMC3,CCNA2,MCM5,CDKN1B,ANAPC7,CDC25B,ORC3,TGFB1,PLK1,RBX1,PRKDC,E2F3,ANAPC2,CDC6,PKMYT1,MCM2,CDC23,SMAD2,CDC16,CDC27,RBL1,E2F4,GADD45B,TFDP1,E2F1,YWHAZ,CHEK2,TFDP2,CCNB2,CDK2,E2F2,YWHAH,SMAD4,ESPL1,CDKN2A,HDAC2,ANAPC4
ko04110	Cell cycle	7.30620671486595e-10	-21.0371267081179	124	48	0.0417754569190601	1149	7161	9232,10912,10926,8454,4998,891,10459,1031,5925,4193,5111,9126,890,4174,1027,51434,994,23595,7040,5347,9978,5591,1871,29882,990,9088,4171,8697,4087,8881,996,5933,1874,4616,7027,1869,7534,11200,7029,9133,1017,1870,7533,4089,9700,1029,3066,29945	PTTG1,GADD45G,DBF4,CUL1,ORC1,CCNB1,MAD2L2,CDKN2C,RB1,MDM2,PCNA,SMC3,CCNA2,MCM5,CDKN1B,ANAPC7,CDC25B,ORC3,TGFB1,PLK1,RBX1,PRKDC,E2F3,ANAPC2,CDC6,PKMYT1,MCM2,CDC23,SMAD2,CDC16,CDC27,RBL1,E2F4,GADD45B,TFDP1,E2F1,YWHAZ,CHEK2,TFDP2,CCNB2,CDK2,E2F2,YWHAH,SMAD4,ESPL1,CDKN2A,HDAC2,ANAPC4
hsa00190	Oxidative phosphorylation	8.05566196874907e-09	-18.6368906425956	120	45	0.0391644908616188	1149	7161	4698,1355,1329,4729,4719,4712,29796,1327,4697,506,526,522,6389,374291,4724,533,4723,4695,4710,23545,4728,4715,1537,4696,9114,5464,9550,535,4701,9551,4707,6390,51382,518,126328,9167,1351,27068,9377,7388,527,4725,498,528,8992	NDUFA5,COX15,COX5B,NDUFV2,NDUFS1,NDUFB6,UQCR10,COX4I1,NDUFA4,ATP5F1B,ATP6V1B2,ATP5PF,SDHA,NDUFS7,NDUFS4,ATP6V0B,NDUFV1,NDUFA2,NDUFB4,ATP6V0A2,NDUFS8,NDUFB9,CYC1,NDUFA3,ATP6V0D1,PPA1,ATP6V1G1,ATP6V0A1,NDUFA7,ATP5MF,NDUFB1,SDHB,ATP6V1D,ATP5MC3,NDUFA11,COX7A2L,COX8A,PPA2,COX5A,UQCRH,ATP6V0C,NDUFS5,ATP5F1A,ATP6V1C1,ATP6V0E1
ko00190	Oxidative phosphorylation	8.05566196874907e-09	-18.6368906425956	120	45	0.0391644908616188	1149	7161	4698,1329,4729,1355,4719,4712,29796,1327,4697,506,526,522,6389,374291,4724,533,4723,4695,4710,23545,4728,4715,1537,4696,5464,9114,9550,535,4701,9551,4707,6390,51382,518,9167,126328,1351,27068,9377,7388,527,4725,498,528,8992	NDUFA5,COX5B,NDUFV2,COX15,NDUFS1,NDUFB6,UQCR10,COX4I1,NDUFA4,ATP5F1B,ATP6V1B2,ATP5PF,SDHA,NDUFS7,NDUFS4,ATP6V0B,NDUFV1,NDUFA2,NDUFB4,ATP6V0A2,NDUFS8,NDUFB9,CYC1,NDUFA3,PPA1,ATP6V0D1,ATP6V1G1,ATP6V0A1,NDUFA7,ATP5MF,NDUFB1,SDHB,ATP6V1D,ATP5MC3,COX7A2L,NDUFA11,COX8A,PPA2,COX5A,UQCRH,ATP6V0C,NDUFS5,ATP5F1A,ATP6V1C1,ATP6V0E1
hsa05010	Alzheimer's disease	1.72714240205723e-07	-15.5716273988774	165	53	0.0461270670147955	1149	7161	4698,1329,4729,4719,4712,102,29796,1327,4697,54205,5532,506,522,5663,83464,351,6389,374291,4724,824,1020,805,4723,4695,488,4710,4728,4715,1537,4696,5530,6868,51107,4701,4707,8772,5595,355,6390,3416,518,126328,9167,1351,5534,9377,7388,22926,498,4725,5594,10313,823	NDUFA5,COX5B,NDUFV2,NDUFS1,NDUFB6,ADAM10,UQCR10,COX4I1,NDUFA4,CYCS,PPP3CB,ATP5F1B,ATP5PF,PSEN1,APH1B,APP,SDHA,NDUFS7,NDUFS4,CAPN2,CDK5,CALM2,NDUFV1,NDUFA2,ATP2A2,NDUFB4,NDUFS8,NDUFB9,CYC1,NDUFA3,PPP3CA,ADAM17,APH1A,NDUFA7,NDUFB1,FADD,MAPK3,FAS,SDHB,IDE,ATP5MC3,NDUFA11,COX7A2L,COX8A,PPP3R1,COX5A,UQCRH,ATF6,ATP5F1A,NDUFS5,MAPK1,RTN3,CAPN1
ko05010	Alzheimer's disease	1.72714240205723e-07	-15.5716273988774	165	53	0.0461270670147955	1149	7161	4698,1329,4729,4719,4712,102,29796,1327,4697,54205,5532,506,522,5663,83464,351,6389,374291,4724,824,1020,805,4723,4695,488,4710,4728,4715,1537,4696,5530,6868,51107,4701,4707,8772,5595,355,6390,3416,518,126328,9167,1351,5534,9377,7388,22926,498,4725,5594,10313,823	NDUFA5,COX5B,NDUFV2,NDUFS1,NDUFB6,ADAM10,UQCR10,COX4I1,NDUFA4,CYCS,PPP3CB,ATP5F1B,ATP5PF,PSEN1,APH1B,APP,SDHA,NDUFS7,NDUFS4,CAPN2,CDK5,CALM2,NDUFV1,NDUFA2,ATP2A2,NDUFB4,NDUFS8,NDUFB9,CYC1,NDUFA3,PPP3CA,ADAM17,APH1A,NDUFA7,NDUFB1,FADD,MAPK3,FAS,SDHB,IDE,ATP5MC3,NDUFA11,COX7A2L,COX8A,PPP3R1,COX5A,UQCRH,ATF6,ATP5F1A,NDUFS5,MAPK1,RTN3,CAPN1
ko04140	Autophagy - animal	1.76732332093475e-07	-15.5486294970332	127	44	0.0382941688424717	1149	7161	7249,5894,5562,64121,55102,84335,598,440275,8678,5566,8837,115201,81671,5728,9110,64422,5296,1612,9776,596,64223,5170,4893,79065,9821,7879,208,3845,55578,5605,1613,51100,6009,5595,1514,8897,5515,7248,9342,6794,26100,5594,3476,3265	TSC2,RAF1,PRKAA1,RRAGC,ATG2B,AKT1S1,BCL2L1,EIF2AK4,BECN1,PRKACA,CFLAR,ATG4A,VMP1,PTEN,MTMR4,ATG3,PIK3R2,DAPK1,ATG13,BCL2,MLST8,PDPK1,NRAS,ATG9A,RB1CC1,RAB7A,AKT2,KRAS,SUPT20H,MAP2K2,DAPK3,SH3GLB1,RHEB,MAPK3,CTSL,MTMR3,PPP2CA,TSC1,SNAP29,STK11,WIPI2,MAPK1,IGBP1,HRAS
hsa04140	Autophagy - animal	1.76732332093475e-07	-15.5486294970332	127	44	0.0382941688424717	1149	7161	7249,5894,5562,64121,55102,84335,598,440275,8678,5566,8837,115201,81671,5728,9110,64422,5296,1612,9776,596,64223,5170,4893,79065,9821,7879,208,3845,55578,5605,1613,51100,6009,5595,1514,8897,5515,7248,9342,6794,26100,5594,3476,3265	TSC2,RAF1,PRKAA1,RRAGC,ATG2B,AKT1S1,BCL2L1,EIF2AK4,BECN1,PRKACA,CFLAR,ATG4A,VMP1,PTEN,MTMR4,ATG3,PIK3R2,DAPK1,ATG13,BCL2,MLST8,PDPK1,NRAS,ATG9A,RB1CC1,RAB7A,AKT2,KRAS,SUPT20H,MAP2K2,DAPK3,SH3GLB1,RHEB,MAPK3,CTSL,MTMR3,PPP2CA,TSC1,SNAP29,STK11,WIPI2,MAPK1,IGBP1,HRAS
ko03013	RNA transport	1.35433762707929e-06	-13.5121980592558	166	51	0.0443864229765013	1149	7161	55706,23511,9984,8480,8664,6613,9939,53371,7329,10289,10605,8761,23165,10073,8894,23225,9775,10248,57122,79833,26019,9972,50628,1983,26986,79902,11171,81929,10460,54913,23191,29107,10921,11218,9631,5905,26999,8087,1982,8666,8667,8661,1207,25929,5976,23636,9818,51068,8086,79760,55916	NDC1,NUP188,THOC1,RAE1,EIF3D,SUMO2,RBM8A,NUP54,UBE2I,EIF1B,PAIP1,PABPC4,NUP205,SNUPN,EIF2S2,NUP210,EIF4A3,POP7,NUP107,GEMIN6,UPF2,NUP153,GEMIN4,EIF5,PABPC1,NUP85,STRAP,SEH1L,TACC3,RPP25,CYFIP1,NXT1,RNPS1,DDX20,NUP155,RANGAP1,CYFIP2,FXR1,EIF4G2,EIF3G,EIF3H,EIF3A,CLNS1A,GEMIN5,UPF1,NUP62,NUP58,NMD3,AAAS,GEMIN7,NXT2
hsa03013	RNA transport	1.35433762707929e-06	-13.5121980592558	166	51	0.0443864229765013	1149	7161	55706,23511,9984,8480,8664,6613,9939,53371,7329,10289,10605,8761,23165,10073,8894,23225,9775,10248,57122,79833,26019,9972,50628,1983,26986,79902,11171,81929,10460,54913,23191,29107,10921,11218,9631,5905,26999,8087,1982,8666,8667,8661,1207,25929,5976,23636,9818,51068,8086,79760,55916	NDC1,NUP188,THOC1,RAE1,EIF3D,SUMO2,RBM8A,NUP54,UBE2I,EIF1B,PAIP1,PABPC4,NUP205,SNUPN,EIF2S2,NUP210,EIF4A3,POP7,NUP107,GEMIN6,UPF2,NUP153,GEMIN4,EIF5,PABPC1,NUP85,STRAP,SEH1L,TACC3,RPP25,CYFIP1,NXT1,RNPS1,DDX20,NUP155,RANGAP1,CYFIP2,FXR1,EIF4G2,EIF3G,EIF3H,EIF3A,CLNS1A,GEMIN5,UPF1,NUP62,NUP58,NMD3,AAAS,GEMIN7,NXT2
hsa03010	Ribosome	2.58803625324107e-06	-12.8646111732162	134	43	0.0374238468233246	1149	7161	6209,6187,65005,6181,51116,64960,6138,9801,6135,6147,6139,64981,6143,65003,219927,200916,64983,6159,11224,6204,6169,6132,6182,6128,6229,55173,54948,63931,6157,6203,3921,25873,6167,51069,6161,6233,6208,51264,6176,2197,28998,11222,6231	RPS15,RPS2,MRPL9,RPLP2,MRPS2,MRPS15,RPL15,MRPL19,RPL11,RPL23A,RPL17,MRPL34,RPL19,MRPL11,MRPL21,RPL22L1,MRPL32,RPL29,RPL35,RPS10,RPL38,RPL8,MRPL12,RPL6,RPS24,MRPS10,MRPL16,MRPS14,RPL27A,RPS9,RPSA,RPL36,RPL37,MRPL2,RPL32,RPS27A,RPS14,MRPL27,RPLP1,FAU,MRPL13,MRPL3,RPS26
ko03010	Ribosome	2.58803625324107e-06	-12.8646111732162	134	43	0.0374238468233246	1149	7161	6209,6187,65005,6181,51116,64960,6138,9801,6135,6147,6139,64981,6143,65003,219927,200916,64983,6159,11224,6132,6182,6204,6128,6169,55173,6229,54948,6157,63931,6203,3921,25873,6167,51069,6161,6233,6208,51264,6176,2197,28998,6231,11222	RPS15,RPS2,MRPL9,RPLP2,MRPS2,MRPS15,RPL15,MRPL19,RPL11,RPL23A,RPL17,MRPL34,RPL19,MRPL11,MRPL21,RPL22L1,MRPL32,RPL29,RPL35,RPL8,MRPL12,RPS10,RPL6,RPL38,MRPS10,RPS24,MRPL16,RPL27A,MRPS14,RPS9,RPSA,RPL36,RPL37,MRPL2,RPL32,RPS27A,RPS14,MRPL27,RPLP1,FAU,MRPL13,RPS26,MRPL3
ko05110	Vibrio cholerae infection	3.8312682893794e-06	-12.4723146635364	51	22	0.0191470844212359	1149	7161	10952,23480,30001,535,375,3784,526,5566,2778,533,51382,29927,115,23545,527,60,528,6558,8992,9114,9550,10945	SEC61B,SEC61G,ERO1A,ATP6V0A1,ARF1,KCNQ1,ATP6V1B2,PRKACA,GNAS,ATP6V0B,ATP6V1D,SEC61A1,ADCY9,ATP6V0A2,ATP6V0C,ACTB,ATP6V1C1,SLC12A2,ATP6V0E1,ATP6V0D1,ATP6V1G1,KDELR1
hsa05110	Vibrio cholerae infection	3.8312682893794e-06	-12.4723146635364	51	22	0.0191470844212359	1149	7161	10952,23480,30001,535,375,3784,526,5566,2778,533,51382,29927,115,23545,527,60,528,6558,8992,9114,9550,10945	SEC61B,SEC61G,ERO1A,ATP6V0A1,ARF1,KCNQ1,ATP6V1B2,PRKACA,GNAS,ATP6V0B,ATP6V1D,SEC61A1,ADCY9,ATP6V0A2,ATP6V0C,ACTB,ATP6V1C1,SLC12A2,ATP6V0E1,ATP6V0D1,ATP6V1G1,KDELR1
ko04120	Ubiquitin mediated proteolysis	4.94012287626725e-06	-12.2181203533355	137	43	0.0374238468233246	1149	7161	7323,7325,9320,331,55585,65264,8454,9354,7329,329,11060,8916,55120,4193,92912,6477,10075,23759,51434,89910,9690,9040,27339,134111,330,9978,7428,8452,29882,10277,672,84447,8697,8881,9817,996,9063,5371,22954,11065,57154,29945,1642	UBE2D3,UBE2E2,TRIP12,XIAP,UBE2Q1,UBE2Z,CUL1,UBE4A,UBE2I,BIRC2,WWP2,HERC3,FANCL,MDM2,UBE2Q2,SIAH1,HUWE1,PPIL2,ANAPC7,UBE3B,UBE3C,UBE2M,PRPF19,UBE2QL1,BIRC3,RBX1,VHL,CUL3,ANAPC2,UBE4B,BRCA1,SYVN1,CDC23,CDC16,KEAP1,CDC27,PIAS2,PML,TRIM32,UBE2C,SMURF1,ANAPC4,DDB1
hsa04120	Ubiquitin mediated proteolysis	4.94012287626725e-06	-12.2181203533355	137	43	0.0374238468233246	1149	7161	7323,7325,9320,331,55585,65264,8454,9354,7329,329,11060,8916,55120,4193,92912,6477,10075,23759,51434,89910,9690,9040,27339,134111,330,9978,7428,8452,29882,10277,672,84447,8697,8881,9817,996,9063,5371,22954,11065,57154,29945,1642	UBE2D3,UBE2E2,TRIP12,XIAP,UBE2Q1,UBE2Z,CUL1,UBE4A,UBE2I,BIRC2,WWP2,HERC3,FANCL,MDM2,UBE2Q2,SIAH1,HUWE1,PPIL2,ANAPC7,UBE3B,UBE3C,UBE2M,PRPF19,UBE2QL1,BIRC3,RBX1,VHL,CUL3,ANAPC2,UBE4B,BRCA1,SYVN1,CDC23,CDC16,KEAP1,CDC27,PIAS2,PML,TRIM32,UBE2C,SMURF1,ANAPC4,DDB1
ko05016	Huntington's disease	5.44757089552108e-06	-12.12034075589	187	54	0.0469973890339426	1149	7161	4698,1329,4729,4719,4712,5440,29796,10540,1327,4697,54205,506,522,6389,374291,4724,4899,4723,4695,4710,163,4728,4715,1537,1212,1385,4696,10126,1639,10105,5438,5436,5441,7417,5433,23186,4701,4707,7416,292,5430,6390,5439,518,126328,9167,1351,9519,9377,7388,498,4725,1175,3066	NDUFA5,COX5B,NDUFV2,NDUFS1,NDUFB6,POLR2K,UQCR10,DCTN2,COX4I1,NDUFA4,CYCS,ATP5F1B,ATP5PF,SDHA,NDUFS7,NDUFS4,NRF1,NDUFV1,NDUFA2,NDUFB4,AP2B1,NDUFS8,NDUFB9,CYC1,CLTB,CREB1,NDUFA3,DNAL4,DCTN1,PPIF,POLR2I,POLR2G,POLR2L,VDAC2,POLR2D,RCOR1,NDUFA7,NDUFB1,VDAC1,SLC25A5,POLR2A,SDHB,POLR2J,ATP5MC3,NDUFA11,COX7A2L,COX8A,TBPL1,COX5A,UQCRH,ATP5F1A,NDUFS5,AP2S1,HDAC2
hsa05016	Huntington's disease	5.44757089552108e-06	-12.12034075589	187	54	0.0469973890339426	1149	7161	4698,1329,4729,4719,4712,5440,29796,10540,1327,4697,54205,506,522,6389,374291,4724,4899,4723,4695,4710,163,4728,4715,1537,1212,1385,4696,10126,1639,10105,5438,5436,5441,7417,5433,23186,4701,4707,7416,292,5430,6390,5439,518,126328,9167,1351,9519,9377,7388,498,4725,1175,3066	NDUFA5,COX5B,NDUFV2,NDUFS1,NDUFB6,POLR2K,UQCR10,DCTN2,COX4I1,NDUFA4,CYCS,ATP5F1B,ATP5PF,SDHA,NDUFS7,NDUFS4,NRF1,NDUFV1,NDUFA2,NDUFB4,AP2B1,NDUFS8,NDUFB9,CYC1,CLTB,CREB1,NDUFA3,DNAL4,DCTN1,PPIF,POLR2I,POLR2G,POLR2L,VDAC2,POLR2D,RCOR1,NDUFA7,NDUFB1,VDAC1,SLC25A5,POLR2A,SDHB,POLR2J,ATP5MC3,NDUFA11,COX7A2L,COX8A,TBPL1,COX5A,UQCRH,ATP5F1A,NDUFS5,AP2S1,HDAC2
hsa05012	Parkinson's disease	1.45350011651807e-05	-11.1389509437896	129	40	0.0348128807658834	1149	7161	4698,1329,4729,4719,4712,29796,1327,4697,54205,506,522,5566,6389,11315,374291,4724,4723,4695,4710,4728,4715,1537,4696,2771,27429,10105,7417,4701,4707,7416,292,6390,518,126328,9167,1351,9377,7388,4725,498	NDUFA5,COX5B,NDUFV2,NDUFS1,NDUFB6,UQCR10,COX4I1,NDUFA4,CYCS,ATP5F1B,ATP5PF,PRKACA,SDHA,PARK7,NDUFS7,NDUFS4,NDUFV1,NDUFA2,NDUFB4,NDUFS8,NDUFB9,CYC1,NDUFA3,GNAI2,HTRA2,PPIF,VDAC2,NDUFA7,NDUFB1,VDAC1,SLC25A5,SDHB,ATP5MC3,NDUFA11,COX7A2L,COX8A,COX5A,UQCRH,NDUFS5,ATP5F1A
ko04144	Endocytosis	1.49761896402366e-05	-11.1090489753661	260	68	0.0591818973020017	1149	7161	27243,10015,9230,80230,9815,8027,4218,4193,8853,998,11021,5867,1785,118813,163,1212,2149,7879,7456,25978,5869,57403,4087,7454,29082,112936,56904,128866,27183,57154,409,1175,56288,60682,3133,9744,11311,29924,375,84313,8766,3105,7037,23396,3799,2261,156,10092,381,829,7040,9267,387,6643,154,830,10552,51100,64744,3304,3106,9146,5371,116985,30844,91782,3265,51699	CHMP2A,PDCD6IP,RAB11B,RUFY1,GIT2,STAM,RAB8A,MDM2,ASAP2,CDC42,RAB35,RAB4A,DNM2,ZFYVE27,AP2B1,CLTB,F2R,RAB7A,WIPF1,CHMP2B,RAB5B,RAB22A,SMAD2,WAS,CHMP4A,VPS26B,SH3GLB2,CHMP4B,VPS4A,SMURF1,ARRB2,AP2S1,PARD3,SMAP1,HLA-E,ACAP1,VPS45,EPN1,ARF1,VPS25,RAB11A,HLA-A,TFRC,PIP5K1C,KIF5B,FGFR3,GRK2,ARPC5,ARF5,CAPZA1,TGFB1,CYTH1,RHOA,SNX2,ADRB2,CAPZA2,ARPC1A,SH3GLB1,SMAP2,HSPA1B,HLA-B,HGS,PML,ARAP1,EHD4,CHMP7,HRAS,VPS29
hsa04144	Endocytosis	1.49761896402366e-05	-11.1090489753661	260	68	0.0591818973020017	1149	7161	27243,10015,9230,80230,9815,8027,4218,4193,8853,998,11021,5867,1785,118813,163,1212,2149,7879,7456,25978,5869,57403,4087,7454,29082,112936,56904,128866,27183,57154,409,1175,56288,60682,3133,9744,11311,29924,375,84313,8766,3105,7037,23396,3799,2261,156,10092,381,829,7040,9267,387,6643,154,830,10552,51100,64744,3304,3106,9146,5371,116985,30844,91782,3265,51699	CHMP2A,PDCD6IP,RAB11B,RUFY1,GIT2,STAM,RAB8A,MDM2,ASAP2,CDC42,RAB35,RAB4A,DNM2,ZFYVE27,AP2B1,CLTB,F2R,RAB7A,WIPF1,CHMP2B,RAB5B,RAB22A,SMAD2,WAS,CHMP4A,VPS26B,SH3GLB2,CHMP4B,VPS4A,SMURF1,ARRB2,AP2S1,PARD3,SMAP1,HLA-E,ACAP1,VPS45,EPN1,ARF1,VPS25,RAB11A,HLA-A,TFRC,PIP5K1C,KIF5B,FGFR3,GRK2,ARPC5,ARF5,CAPZA1,TGFB1,CYTH1,RHOA,SNX2,ADRB2,CAPZA2,ARPC1A,SH3GLB1,SMAP2,HSPA1B,HLA-B,HGS,PML,ARAP1,EHD4,CHMP7,HRAS,VPS29
hsa04142	Lysosome	2.59480569064588e-05	-10.5594138295197	123	38	0.0330722367275892	1149	7161	26088,4126,3074,10947,427,285362,4125,23062,162,1176,2799,533,1520,10239,8907,23545,1212,9114,2760,51172,53,2581,5538,2629,535,26503,23431,4758,1514,950,6448,4669,1174,527,5476,5660,1201,3073	GGA1,MANBA,HEXB,AP3M2,ASAH1,SUMF1,MAN2B1,GGA2,AP1B1,AP3S1,GNS,ATP6V0B,CTSS,AP3S2,AP1M1,ATP6V0A2,CLTB,ATP6V0D1,GM2A,NAGPA,ACP2,GALC,PPT1,GBA,ATP6V0A1,SLC17A5,AP4E1,NEU1,CTSL,SCARB2,SGSH,NAGLU,AP1S1,ATP6V0C,CTSA,PSAP,CLN3,HEXA
ko04142	Lysosome	2.59480569064588e-05	-10.5594138295197	123	38	0.0330722367275892	1149	7161	26088,4126,3074,10947,427,285362,4125,23062,162,1176,2799,533,1520,10239,8907,23545,1212,9114,2760,51172,53,2581,5538,2629,535,26503,23431,4758,1514,950,6448,4669,1174,527,5476,5660,1201,3073	GGA1,MANBA,HEXB,AP3M2,ASAH1,SUMF1,MAN2B1,GGA2,AP1B1,AP3S1,GNS,ATP6V0B,CTSS,AP3S2,AP1M1,ATP6V0A2,CLTB,ATP6V0D1,GM2A,NAGPA,ACP2,GALC,PPT1,GBA,ATP6V0A1,SLC17A5,AP4E1,NEU1,CTSL,SCARB2,SGSH,NAGLU,AP1S1,ATP6V0C,CTSA,PSAP,CLN3,HEXA
hsa_M00355	Spliceosome, 35S U5-snRNP	7.7948492876177e-05	-9.4594622971416	37	16	0.0139251523063534	1149	7161	51362,23020,56949,6628,10450,51340,6634,3304,9343,8896,55094,9716,6637,100534599,988,27339	CDC40,SNRNP200,XAB2,SNRPB,PPIE,CRNKL1,SNRPD3,HSPA1B,EFTUD2,BUD31,GPATCH1,AQR,SNRPG,ISY1-RAB43,CDC5L,PRPF19
M00355	Spliceosome, 35S U5-snRNP	7.7948492876177e-05	-9.4594622971416	37	16	0.0139251523063534	1149	7161	51362,23020,56949,6628,10450,51340,6634,3304,9343,8896,55094,9716,6637,100534599,988,27339	CDC40,SNRNP200,XAB2,SNRPB,PPIE,CRNKL1,SNRPD3,HSPA1B,EFTUD2,BUD31,GPATCH1,AQR,SNRPG,ISY1-RAB43,CDC5L,PRPF19
hsa01524	Platinum drug resistance	9.92918091828223e-05	-9.21744747588604	73	25	0.0217580504786771	1149	7161	5170,578,2067,330,208,331,7155,54205,672,598,329,8772,5595,355,1317,4193,332,7507,5296,4436,596,4217,5594,2956,1029	PDPK1,BAK1,ERCC1,BIRC3,AKT2,XIAP,TOP2B,CYCS,BRCA1,BCL2L1,BIRC2,FADD,MAPK3,FAS,SLC31A1,MDM2,BIRC5,XPA,PIK3R2,MSH2,BCL2,MAP3K5,MAPK1,MSH6,CDKN2A
ko01524	Platinum drug resistance	9.92918091828223e-05	-9.21744747588604	73	25	0.0217580504786771	1149	7161	5170,578,2067,330,208,331,7155,54205,672,598,329,8772,5595,355,1317,4193,332,7507,5296,4436,596,4217,5594,2956,1029	PDPK1,BAK1,ERCC1,BIRC3,AKT2,XIAP,TOP2B,CYCS,BRCA1,BCL2L1,BIRC2,FADD,MAPK3,FAS,SLC31A1,MDM2,BIRC5,XPA,PIK3R2,MSH2,BCL2,MAP3K5,MAPK1,MSH6,CDKN2A
hsa05161	Hepatitis B	0.000221706425062023	-8.41415646087776	144	40	0.0348128807658834	1149	7161	23586,5894,54205,3661,5925,4775,5111,890,5728,5296,1027,596,57506,1385,1386,6774,7040,4893,208,1871,3845,4773,2002,5605,8772,5595,355,3716,332,6778,1869,6772,7534,148022,5594,1870,1017,3265,4089,1642	DDX58,RAF1,CYCS,IRF3,RB1,NFATC3,PCNA,CCNA2,PTEN,PIK3R2,CDKN1B,BCL2,MAVS,CREB1,ATF2,STAT3,TGFB1,NRAS,AKT2,E2F3,KRAS,NFATC2,ELK1,MAP2K2,FADD,MAPK3,FAS,JAK1,BIRC5,STAT6,E2F1,STAT1,YWHAZ,TICAM1,MAPK1,E2F2,CDK2,HRAS,SMAD4,DDB1
hsa00270	Cysteine and methionine metabolism	0.000249251068095026	-8.2970498638957	44	17	0.0147954743255004	1149	7161	6723,27430,2730,1788,2806,4191,262,84245,3939,191,4190,10768,1786,4548,4144,587,3945	SRM,MAT2B,GCLM,DNMT3A,GOT2,MDH2,AMD1,MRI1,LDHA,AHCY,MDH1,AHCYL1,DNMT1,MTR,MAT2A,BCAT2,LDHB
ko00270	Cysteine and methionine metabolism	0.000249251068095026	-8.2970498638957	44	17	0.0147954743255004	1149	7161	6723,27430,2730,1788,2806,4191,262,84245,3939,191,4190,10768,1786,4548,4144,587,3945	SRM,MAT2B,GCLM,DNMT3A,GOT2,MDH2,AMD1,MRI1,LDHA,AHCY,MDH1,AHCYL1,DNMT1,MTR,MAT2A,BCAT2,LDHB
ko05219	Bladder cancer	0.000330094882218862	-8.0161304229549	41	16	0.0139251523063534	1149	7161	4893,5894,1871,3845,5605,1613,5595,5925,2261,4193,1612,1869,1870,5594,3265,1029	NRAS,RAF1,E2F3,KRAS,MAP2K2,DAPK3,MAPK3,RB1,FGFR3,MDM2,DAPK1,E2F1,E2F2,MAPK1,HRAS,CDKN2A
hsa05219	Bladder cancer	0.000330094882218862	-8.0161304229549	41	16	0.0139251523063534	1149	7161	4893,5894,1871,3845,5605,1613,5595,5925,2261,4193,1612,1869,1870,5594,3265,1029	NRAS,RAF1,E2F3,KRAS,MAP2K2,DAPK3,MAPK3,RB1,FGFR3,MDM2,DAPK1,E2F1,E2F2,MAPK1,HRAS,CDKN2A
M00427	Nuclear pore complex	0.000341542317857421	-7.9820389690393	45	17	0.0147954743255004	1149	7161	55706,23511,8480,6613,53371,9631,5905,7329,23165,23225,57122,23636,9972,9818,79902,8086,81929	NDC1,NUP188,RAE1,SUMO2,NUP54,NUP155,RANGAP1,UBE2I,NUP205,NUP210,NUP107,NUP62,NUP153,NUP58,NUP85,AAAS,SEH1L
hsa_M00427	Nuclear pore complex	0.000341542317857421	-7.9820389690393	45	17	0.0147954743255004	1149	7161	55706,23511,8480,6613,53371,9631,5905,7329,23165,23225,57122,23636,9972,9818,79902,8086,81929	NDC1,NUP188,RAE1,SUMO2,NUP54,NUP155,RANGAP1,UBE2I,NUP205,NUP210,NUP107,NUP62,NUP153,NUP58,NUP85,AAAS,SEH1L
hsa_M00354	Spliceosome, U4/U6.U5 tri-snRNP	0.000357183430740883	-7.9372610965415	30	13	0.0113141862489121	1149	7161	9092,23020,11157,6628,9343,51691,10713,9128,9129,6637,6634,10907,9416	SART1,SNRNP200,LSM6,SNRPB,EFTUD2,LSM8,USP39,PRPF4,PRPF3,SNRPG,SNRPD3,TXNL4A,DDX23
M00354	Spliceosome, U4/U6.U5 tri-snRNP	0.000357183430740883	-7.9372610965415	30	13	0.0113141862489121	1149	7161	9092,23020,11157,6628,9343,51691,10713,9128,9129,6637,6634,10907,9416	SART1,SNRNP200,LSM6,SNRPB,EFTUD2,LSM8,USP39,PRPF4,PRPF3,SNRPG,SNRPD3,TXNL4A,DDX23
hsa04914	Progesterone-mediated oocyte maturation	0.000384302917395624	-7.86407946896868	92	28	0.0243690165361184	1149	7161	5347,5894,6195,208,3845,29882,9088,8697,891,1432,5140,5566,10459,5595,890,8881,996,5296,115,51434,994,5594,9133,1017,2771,132864,29945,113	PLK1,RAF1,RPS6KA1,AKT2,KRAS,ANAPC2,PKMYT1,CDC23,CCNB1,MAPK14,PDE3B,PRKACA,MAD2L2,MAPK3,CCNA2,CDC16,CDC27,PIK3R2,ADCY9,ANAPC7,CDC25B,MAPK1,CCNB2,CDK2,GNAI2,CPEB2,ANAPC4,ADCY7
ko04914	Progesterone-mediated oocyte maturation	0.000384302917395624	-7.86407946896868	92	28	0.0243690165361184	1149	7161	5347,5894,6195,208,3845,29882,9088,8697,891,1432,5140,5566,10459,5595,890,8881,996,5296,115,51434,994,5594,9133,1017,2771,132864,29945,113	PLK1,RAF1,RPS6KA1,AKT2,KRAS,ANAPC2,PKMYT1,CDC23,CCNB1,MAPK14,PDE3B,PRKACA,MAD2L2,MAPK3,CCNA2,CDC16,CDC27,PIK3R2,ADCY9,ANAPC7,CDC25B,MAPK1,CCNB2,CDK2,GNAI2,CPEB2,ANAPC4,ADCY7
hsa04114	Oocyte meiosis	0.000431532853326491	-7.74816691285013	120	34	0.0295909486510009	1149	7161	6195,9232,8454,5532,891,5566,10459,26271,805,9126,115,51434,818,113,5347,5530,9978,29882,9088,8697,5595,5515,8881,5525,996,5534,7534,1017,7533,9133,5594,132864,9700,29945	RPS6KA1,PTTG1,CUL1,PPP3CB,CCNB1,PRKACA,MAD2L2,FBXO5,CALM2,SMC3,ADCY9,ANAPC7,CAMK2G,ADCY7,PLK1,PPP3CA,RBX1,ANAPC2,PKMYT1,CDC23,MAPK3,PPP2CA,CDC16,PPP2R5A,CDC27,PPP3R1,YWHAZ,CDK2,YWHAH,CCNB2,MAPK1,CPEB2,ESPL1,ANAPC4
ko04114	Oocyte meiosis	0.000431532853326491	-7.74816691285013	120	34	0.0295909486510009	1149	7161	6195,9232,8454,5532,891,5566,10459,26271,805,9126,115,51434,818,113,5347,5530,9978,29882,9088,8697,5595,5515,8881,5525,996,5534,7534,1017,7533,9133,5594,132864,9700,29945	RPS6KA1,PTTG1,CUL1,PPP3CB,CCNB1,PRKACA,MAD2L2,FBXO5,CALM2,SMC3,ADCY9,ANAPC7,CAMK2G,ADCY7,PLK1,PPP3CA,RBX1,ANAPC2,PKMYT1,CDC23,MAPK3,PPP2CA,CDC16,PPP2R5A,CDC27,PPP3R1,YWHAZ,CDK2,YWHAH,CCNB2,MAPK1,CPEB2,ESPL1,ANAPC4
hsa01100	Metabolic pathways	0.000442024389465867	-7.72414549762189	1256	242	0.210617928633594	1149	7161	51816,6723,23649,1355,93183,79717,4712,10007,9091,29796,3074,7841,56922,10554,2746,2992,54187,10423,4942,522,51728,587,2806,54928,60490,3032,51102,231,8801,139596,4715,30834,1786,4249,8813,51056,6241,51809,4953,5557,4122,10195,10555,3703,4669,55278,23417,9377,7388,6483,527,55568,200895,56994,54480,8992,5214,8704,22928,4729,1329,23556,4594,5440,84890,6240,427,2683,4697,1327,54205,8702,2053,374291,4724,1119,2799,57026,56913,6184,3632,471,1603,622,1503,23545,191,5833,1537,27034,5832,79888,9114,223,2222,84284,5438,51604,5558,7264,9489,50814,11253,262,2181,157506,2629,1635,5315,4548,221830,51109,55361,159,6390,2058,10797,2590,5439,6675,5859,1633,5634,47,254531,4190,498,2821,55627,140838,3073,9791,4698,1788,7360,8802,4191,7389,7371,83549,10329,1120,83440,526,9453,253558,6389,2132,80308,533,9110,1854,9663,1431,6185,6888,9562,10768,9550,51703,5441,5436,5538,3419,1371,5433,9107,535,4967,4701,4707,11232,8050,4144,221,5445,1650,253782,115024,126328,154141,8566,8703,4048,2584,55191,55907,2730,8760,4719,84245,10020,7086,56894,506,6697,10654,4121,23396,10682,27430,2618,4723,283459,4695,4710,2530,4728,10728,84172,4696,3613,3945,126792,271,7083,53,2987,2581,3939,84265,158,133686,9551,5430,8897,23646,6448,51382,5426,518,51,1351,3614,38,34,4725,528,3420,5223,112483,2653	ADA2,SRM,POLA2,COX15,PIGM,PPCS,NDUFB6,GNPDA1,PIGQ,UQCR10,HEXB,MOGS,MCCC1,AGPAT1,GLUD1,GYG1,NANS,CDIPT,OAT,ATP5PF,POLR3K,BCAT2,GOT2,IMPAD1,PPCDC,HADHB,MECR,AKR1B1,SUCLG2,UPRT,NDUFB9,ZNRD1,DNMT1,MGAT5,DPM1,LAP3,RRM2,GALNT7,ODC1,PRIM1,MAN2A2,ALG3,AGPAT2,STT3A,NAGLU,QRSL1,MLYCD,COX5A,UQCRH,ST3GAL2,ATP6V0C,GALNT10,DHFR2,CHPT1,CHPF2,ATP6V0E1,PFKP,B4GALT2,SEPHS2,NDUFV2,COX5B,PIGN,MUT,POLR2K,ADO,RRM1,ASAH1,B4GALT1,NDUFA4,COX4I1,CYCS,B4GALT4,EPHX2,NDUFS7,NDUFS4,CHKA,GNS,PDXP,C1GALT1,RPN1,INPP5A,ATIC,DAD1,BDH1,CTPS1,ATP6V0A2,AHCY,PCYT2,CYC1,ACAD8,ALDH18A1,LPCAT1,ATP6V0D1,ALDH9A1,FDFT1,NTPCR,POLR2I,PIGT,PRIM2,TSTA3,PGS1,NSDHL,MAN1B1,AMD1,ACSL3,RDH10,GBA,DCTD,PKM,MTR,TWISTNB,RDH11,PI4K2A,ADSS,SDHB,EPRS,MTHFD2,GALNT2,POLR2J,UAP1,QARS,DCK,PRPS2,ACLY,LPCAT4,MDH1,ATP5F1A,GPI,SMPD4,NANP,HEXA,PTDSS1,NDUFA5,DNMT3A,UGP2,SUCLG1,MDH2,UROD,UCK2,UCK1,RXYLT1,CHKB,ADPGK,ATP6V1B2,GGPS1,LCLAT1,SDHA,EXT2,FLAD1,ATP6V0B,MTMR4,DUT,LPIN2,CS,RPN2,TALDO1,MINPP1,AHCYL1,ATP6V1G1,ACSL5,POLR2L,POLR2G,PPT1,IDH3A,CPOX,POLR2D,MTMR6,ATP6V0A1,OGDH,NDUFA7,NDUFB1,POLG2,PDHX,MAT2A,ALDH3B1,PON2,DDOST,CERS6,NT5C3B,NDUFA11,MBOAT1,PDXK,B4GALT3,LTA4H,GALK1,NADSYN1,CMAS,GCLM,CDS2,NDUFS1,MRI1,GNE,TKT,AGPAT3,ATP5F1B,SPR,PMVK,MAN1A1,PIP5K1C,EBP,MAT2B,GART,NDUFV1,GATC,NDUFA2,NDUFB4,FUT8,NDUFS8,PTGES3,POLR1B,NDUFA3,IMPA2,LDHB,B3GALT6,AMPD2,TK1,ACP2,GUK1,GALC,LDHA,POLR3GL,ADSL,NADK2,ATP5MF,POLR2A,MTMR3,PLD3,SGSH,ATP6V1D,POLE,ATP5MC3,ACOX1,COX8A,IMPDH1,ACAT1,ACADM,NDUFS5,ATP6V1C1,IDH3B,PGAM1,SAT2,GCSH
hsa05220	Chronic myeloid leukemia	0.000468929626118112	-7.66505785169763	71	23	0.0200174064403829	1149	7161	7040,4893,5894,208,1871,3845,598,5605,5595,1399,5925,4193,6464,5296,1869,5781,1027,5594,1870,3265,4089,1029,3066	TGFB1,NRAS,RAF1,AKT2,E2F3,KRAS,BCL2L1,MAP2K2,MAPK3,CRKL,RB1,MDM2,SHC1,PIK3R2,E2F1,PTPN11,CDKN1B,MAPK1,E2F2,HRAS,SMAD4,CDKN2A,HDAC2
ko05220	Chronic myeloid leukemia	0.000468929626118112	-7.66505785169763	71	23	0.0200174064403829	1149	7161	7040,4893,5894,208,1871,3845,598,5605,5595,1399,5925,4193,6464,5296,1869,5781,1027,5594,1870,3265,4089,1029,3066	TGFB1,NRAS,RAF1,AKT2,E2F3,KRAS,BCL2L1,MAP2K2,MAPK3,CRKL,RB1,MDM2,SHC1,PIK3R2,E2F1,PTPN11,CDKN1B,MAPK1,E2F2,HRAS,SMAD4,CDKN2A,HDAC2
M00143	NADH dehydrogenase (ubiquinone) Fe-S protein/flavoprotein complex, mitochondria	0.000488612392367921	-7.62394103644974	11	7	0.00609225413402959	1149	7161	4729,4728,4723,4725,4719,374291,4724	NDUFV2,NDUFS8,NDUFV1,NDUFS5,NDUFS1,NDUFS7,NDUFS4
hsa_M00143	NADH dehydrogenase (ubiquinone) Fe-S protein/flavoprotein complex, mitochondria	0.000488612392367921	-7.62394103644974	11	7	0.00609225413402959	1149	7161	4729,4728,4723,4725,4719,374291,4724	NDUFV2,NDUFS8,NDUFV1,NDUFS5,NDUFS1,NDUFS7,NDUFS4
ko05169	Epstein-Barr virus infection	0.000556017682688855	-7.49471046082219	199	50	0.0435161009573542	1149	7161	23586,7874,9612,5440,3133,1457,3661,440275,27044,1432,5566,4067,51728,3105,5925,5708,4193,5707,890,5296,1027,596,9020,1386,6774,5438,5441,5436,7128,208,5433,84265,27102,5430,3304,5704,3106,3716,5439,23118,5709,5714,9519,7534,3516,1017,7188,7533,5700,3066	DDX58,USP7,NCOR2,POLR2K,HLA-E,CSNK2A1,IRF3,EIF2AK4,SND1,MAPK14,PRKACA,LYN,POLR3K,HLA-A,RB1,PSMD2,MDM2,PSMD1,CCNA2,PIK3R2,CDKN1B,BCL2,MAP3K14,ATF2,STAT3,POLR2I,POLR2L,POLR2G,TNFAIP3,AKT2,POLR2D,POLR3GL,EIF2AK1,POLR2A,HSPA1B,PSMC4,HLA-B,JAK1,POLR2J,TAB2,PSMD3,PSMD8,TBPL1,YWHAZ,RBPJ,CDK2,TRAF5,YWHAH,PSMC1,HDAC2
hsa05169	Epstein-Barr virus infection	0.000556017682688855	-7.49471046082219	199	50	0.0435161009573542	1149	7161	23586,7874,9612,5440,3133,1457,3661,440275,27044,1432,5566,4067,51728,3105,5925,5708,4193,5707,890,5296,1027,596,9020,1386,6774,5438,5441,5436,7128,208,5433,84265,27102,5430,3304,5704,3106,3716,5439,23118,5709,5714,9519,7534,3516,1017,7188,7533,5700,3066	DDX58,USP7,NCOR2,POLR2K,HLA-E,CSNK2A1,IRF3,EIF2AK4,SND1,MAPK14,PRKACA,LYN,POLR3K,HLA-A,RB1,PSMD2,MDM2,PSMD1,CCNA2,PIK3R2,CDKN1B,BCL2,MAP3K14,ATF2,STAT3,POLR2I,POLR2L,POLR2G,TNFAIP3,AKT2,POLR2D,POLR3GL,EIF2AK1,POLR2A,HSPA1B,PSMC4,HLA-B,JAK1,POLR2J,TAB2,PSMD3,PSMD8,TBPL1,YWHAZ,RBPJ,CDK2,TRAF5,YWHAH,PSMC1,HDAC2
ko05212	Pancreatic cancer	0.00067479297961744	-7.3011046109959	64	21	0.0182767624020888	1149	7161	7040,5894,208,5879,1871,3845,598,5595,5925,4087,3716,998,5899,5296,1869,6772,6774,1870,5594,4089,1029	TGFB1,RAF1,AKT2,RAC1,E2F3,KRAS,BCL2L1,MAPK3,RB1,SMAD2,JAK1,CDC42,RALB,PIK3R2,E2F1,STAT1,STAT3,E2F2,MAPK1,SMAD4,CDKN2A
hsa05212	Pancreatic cancer	0.00067479297961744	-7.3011046109959	64	21	0.0182767624020888	1149	7161	7040,5894,208,5879,1871,3845,598,5595,5925,4087,3716,998,5899,5296,1869,6772,6774,1870,5594,4089,1029	TGFB1,RAF1,AKT2,RAC1,E2F3,KRAS,BCL2L1,MAPK3,RB1,SMAD2,JAK1,CDC42,RALB,PIK3R2,E2F1,STAT1,STAT3,E2F2,MAPK1,SMAD4,CDKN2A
hsa_M00177	Ribosome, eukaryotes	0.000754415795695782	-7.18956688877332	91	27	0.0234986945169713	1149	7161	6209,6159,11224,6187,6181,6132,6204,6128,6169,6138,6229,6157,6203,3921,6135,6147,25873,6167,6161,6139,6233,6208,6176,6143,2197,6231,200916	RPS15,RPL29,RPL35,RPS2,RPLP2,RPL8,RPS10,RPL6,RPL38,RPL15,RPS24,RPL27A,RPS9,RPSA,RPL11,RPL23A,RPL36,RPL37,RPL32,RPL17,RPS27A,RPS14,RPLP1,RPL19,FAU,RPS26,RPL22L1
M00177	Ribosome, eukaryotes	0.000754415795695782	-7.18956688877332	91	27	0.0234986945169713	1149	7161	6209,6159,11224,6187,6181,6132,6204,6128,6169,6138,6229,6157,6203,3921,6135,6147,25873,6167,6161,6139,6233,6208,6176,6143,2197,6231,200916	RPS15,RPL29,RPL35,RPS2,RPLP2,RPL8,RPS10,RPL6,RPL38,RPL15,RPS24,RPL27A,RPS9,RPSA,RPL11,RPL23A,RPL36,RPL37,RPL32,RPL17,RPS27A,RPS14,RPLP1,RPL19,FAU,RPS26,RPL22L1
ko04932	Non-alcoholic fatty liver disease (NAFLD)	0.00107633289874294	-6.83419547964353	145	38	0.0330722367275892	1149	7161	4698,4729,5564,1329,4719,4712,29796,5879,5562,4697,1327,54205,6389,374291,4724,4723,6945,4695,998,4710,5296,4715,4728,1537,4696,7040,208,4701,4707,355,6390,9167,126328,1351,9377,7388,4725,4217	NDUFA5,NDUFV2,PRKAB1,COX5B,NDUFS1,NDUFB6,UQCR10,RAC1,PRKAA1,NDUFA4,COX4I1,CYCS,SDHA,NDUFS7,NDUFS4,NDUFV1,MLX,NDUFA2,CDC42,NDUFB4,PIK3R2,NDUFB9,NDUFS8,CYC1,NDUFA3,TGFB1,AKT2,NDUFA7,NDUFB1,FAS,SDHB,COX7A2L,NDUFA11,COX8A,COX5A,UQCRH,NDUFS5,MAP3K5
hsa04932	Non-alcoholic fatty liver disease (NAFLD)	0.00107633289874294	-6.83419547964353	145	38	0.0330722367275892	1149	7161	4698,4729,5564,1329,4719,4712,29796,5879,5562,4697,1327,54205,6389,374291,4724,4723,6945,4695,998,4710,5296,4715,4728,1537,4696,7040,208,4701,4707,355,6390,9167,126328,1351,9377,7388,4725,4217	NDUFA5,NDUFV2,PRKAB1,COX5B,NDUFS1,NDUFB6,UQCR10,RAC1,PRKAA1,NDUFA4,COX4I1,CYCS,SDHA,NDUFS7,NDUFS4,NDUFV1,MLX,NDUFA2,CDC42,NDUFB4,PIK3R2,NDUFB9,NDUFS8,CYC1,NDUFA3,TGFB1,AKT2,NDUFA7,NDUFB1,FAS,SDHB,COX7A2L,NDUFA11,COX8A,COX5A,UQCRH,NDUFS5,MAP3K5
M00009	Citrate cycle (TCA cycle, Krebs cycle)	0.00110009705422611	-6.8123568719553	22	10	0.00870322019147084	1149	7161	6390,8802,4191,3419,1431,8801,4190,4967,3420,6389	SDHB,SUCLG1,MDH2,IDH3A,CS,SUCLG2,MDH1,OGDH,IDH3B,SDHA
hsa_M00009	Citrate cycle (TCA cycle, Krebs cycle)	0.00110009705422611	-6.8123568719553	22	10	0.00870322019147084	1149	7161	6390,8802,4191,3419,1431,8801,4190,4967,3420,6389	SDHB,SUCLG1,MDH2,IDH3A,CS,SUCLG2,MDH1,OGDH,IDH3B,SDHA
hsa05166	HTLV-I infection	0.00112037523150528	-6.79409162165481	256	60	0.0522193211488251	1149	7161	3133,6929,6513,9232,331,5532,598,2113,5566,3105,8323,1390,1031,5925,4775,5111,5296,115,51434,1385,9020,4603,1386,1856,113,7040,5530,4893,2648,208,1871,7417,4605,29882,4773,3845,8697,2002,7416,292,3106,4087,8881,3716,996,5426,2114,2874,81029,5534,9519,1869,1855,11200,9133,1870,4089,3265,29945,1029	HLA-E,TCF3,SLC2A1,PTTG1,XIAP,PPP3CB,BCL2L1,ETS1,PRKACA,HLA-A,FZD6,CREM,CDKN2C,RB1,NFATC3,PCNA,PIK3R2,ADCY9,ANAPC7,CREB1,MAP3K14,MYBL1,ATF2,DVL2,ADCY7,TGFB1,PPP3CA,NRAS,KAT2A,AKT2,E2F3,VDAC2,MYBL2,ANAPC2,NFATC2,KRAS,CDC23,ELK1,VDAC1,SLC25A5,HLA-B,SMAD2,CDC16,JAK1,CDC27,POLE,ETS2,GPS2,WNT5B,PPP3R1,TBPL1,E2F1,DVL1,CHEK2,CCNB2,E2F2,SMAD4,HRAS,ANAPC4,CDKN2A
ko05166	HTLV-I infection	0.00112037523150528	-6.79409162165481	256	60	0.0522193211488251	1149	7161	3133,6929,6513,9232,331,5532,598,2113,5566,3105,8323,1390,1031,5925,4775,5111,5296,115,51434,1385,9020,4603,1386,1856,113,7040,5530,4893,2648,208,1871,7417,4605,29882,4773,3845,8697,2002,7416,292,3106,4087,8881,3716,996,5426,2114,2874,81029,5534,9519,1869,1855,11200,9133,1870,4089,3265,29945,1029	HLA-E,TCF3,SLC2A1,PTTG1,XIAP,PPP3CB,BCL2L1,ETS1,PRKACA,HLA-A,FZD6,CREM,CDKN2C,RB1,NFATC3,PCNA,PIK3R2,ADCY9,ANAPC7,CREB1,MAP3K14,MYBL1,ATF2,DVL2,ADCY7,TGFB1,PPP3CA,NRAS,KAT2A,AKT2,E2F3,VDAC2,MYBL2,ANAPC2,NFATC2,KRAS,CDC23,ELK1,VDAC1,SLC25A5,HLA-B,SMAD2,CDC16,JAK1,CDC27,POLE,ETS2,GPS2,WNT5B,PPP3R1,TBPL1,E2F1,DVL1,CHEK2,CCNB2,E2F2,SMAD4,HRAS,ANAPC4,CDKN2A
hsa05223	Non-small cell lung cancer	0.00122570016052071	-6.70424303865469	58	19	0.0165361183637946	1149	7161	5170,4893,5894,208,1871,3845,2309,5605,27436,5595,6257,5925,5296,1869,1870,5594,6774,3265,1029	PDPK1,NRAS,RAF1,AKT2,E2F3,KRAS,FOXO3,MAP2K2,EML4,MAPK3,RXRB,RB1,PIK3R2,E2F1,E2F2,MAPK1,STAT3,HRAS,CDKN2A
ko05223	Non-small cell lung cancer	0.00122570016052071	-6.70424303865469	58	19	0.0165361183637946	1149	7161	5170,4893,5894,208,1871,3845,2309,5605,27436,5595,6257,5925,5296,1869,1870,5594,6774,3265,1029	PDPK1,NRAS,RAF1,AKT2,E2F3,KRAS,FOXO3,MAP2K2,EML4,MAPK3,RXRB,RB1,PIK3R2,E2F1,E2F2,MAPK1,STAT3,HRAS,CDKN2A
hsa03460	Fanconi anemia pathway	0.00130459147012601	-6.64186533692964	54	18	0.0156657963446475	1149	7161	9894,2067,51426,116028,5395,7156,672,641,2178,80010,55215,57599,6117,6118,55120,5889,79728,80233	TELO2,ERCC1,POLK,RMI2,PMS2,TOP3A,BRCA1,BLM,FANCE,RMI1,FANCI,WDR48,RPA1,RPA2,FANCL,RAD51C,PALB2,FAAP100
ko03460	Fanconi anemia pathway	0.00130459147012601	-6.64186533692964	54	18	0.0156657963446475	1149	7161	9894,2067,51426,116028,5395,7156,672,641,2178,80010,55215,57599,6117,6118,55120,5889,79728,80233	TELO2,ERCC1,POLK,RMI2,PMS2,TOP3A,BRCA1,BLM,FANCE,RMI1,FANCI,WDR48,RPA1,RPA2,FANCL,RAD51C,PALB2,FAAP100
hsa04210	Apoptosis	0.00157131627986225	-6.45584161606182	138	36	0.031331592689295	1149	7161	839,5894,10912,331,54205,598,329,4000,8837,824,1520,5296,596,9020,27429,6709,578,5170,4893,330,208,143,4170,3845,5605,8772,355,5595,1514,332,4616,60,4217,5594,3265,823	CASP6,RAF1,GADD45G,XIAP,CYCS,BCL2L1,BIRC2,LMNA,CFLAR,CAPN2,CTSS,PIK3R2,BCL2,MAP3K14,HTRA2,SPTAN1,BAK1,PDPK1,NRAS,BIRC3,AKT2,PARP4,MCL1,KRAS,MAP2K2,FADD,FAS,MAPK3,CTSL,BIRC5,GADD45B,ACTB,MAP3K5,MAPK1,HRAS,CAPN1
ko04210	Apoptosis	0.00157131627986225	-6.45584161606182	138	36	0.031331592689295	1149	7161	839,5894,10912,331,54205,598,329,4000,8837,824,1520,5296,596,9020,27429,6709,578,5170,4893,330,208,143,4170,3845,5605,8772,355,5595,1514,332,4616,60,4217,5594,3265,823	CASP6,RAF1,GADD45G,XIAP,CYCS,BCL2L1,BIRC2,LMNA,CFLAR,CAPN2,CTSS,PIK3R2,BCL2,MAP3K14,HTRA2,SPTAN1,BAK1,PDPK1,NRAS,BIRC3,AKT2,PARP4,MCL1,KRAS,MAP2K2,FADD,FAS,MAPK3,CTSL,BIRC5,GADD45B,ACTB,MAP3K5,MAPK1,HRAS,CAPN1
M00295	BRCA1-associated genome surveillance complex (BASC)	0.00164556614592666	-6.4096707923173	16	8	0.00696257615317668	1149	7161	5983,672,5111,641,5982,2956,5395,4436	RFC3,BRCA1,PCNA,BLM,RFC2,MSH6,PMS2,MSH2
hsa_M00295	BRCA1-associated genome surveillance complex (BASC)	0.00164556614592666	-6.4096707923173	16	8	0.00696257615317668	1149	7161	5983,672,5111,641,5982,2956,5395,4436	RFC3,BRCA1,PCNA,BLM,RFC2,MSH6,PMS2,MSH2
M00072	N-glycosylation by oligosaccharyltransferase	0.00166676535049853	-6.39687044666989	7	5	0.00435161009573542	1149	7161	6185,6184,1650,3703,1603	RPN2,RPN1,DDOST,STT3A,DAD1
hsa_M00072	N-glycosylation by oligosaccharyltransferase	0.00166676535049853	-6.39687044666989	7	5	0.00435161009573542	1149	7161	6185,6184,1650,3703,1603	RPN2,RPN1,DDOST,STT3A,DAD1
ko05211	Renal cell carcinoma	0.00177004276234572	-6.33675157317088	64	20	0.0174064403829417	1149	7161	7040,4893,9978,7428,5894,208,6513,5879,3845,2113,5605,5595,1399,5906,998,5296,5781,5594,3265,54583	TGFB1,NRAS,RBX1,VHL,RAF1,AKT2,SLC2A1,RAC1,KRAS,ETS1,MAP2K2,MAPK3,CRKL,RAP1A,CDC42,PIK3R2,PTPN11,MAPK1,HRAS,EGLN1
hsa05211	Renal cell carcinoma	0.00177004276234572	-6.33675157317088	64	20	0.0174064403829417	1149	7161	7040,4893,9978,7428,5894,208,6513,5879,3845,2113,5605,5595,1399,5906,998,5296,5781,5594,3265,54583	TGFB1,NRAS,RBX1,VHL,RAF1,AKT2,SLC2A1,RAC1,KRAS,ETS1,MAP2K2,MAPK3,CRKL,RAP1A,CDC42,PIK3R2,PTPN11,MAPK1,HRAS,EGLN1
ko05210	Colorectal cancer	0.00192325842935535	-6.25373443276451	60	19	0.0165361183637946	1149	7161	7040,387,5894,208,5879,3845,54205,26060,5595,4087,332,8312,5296,4436,8313,596,5594,4089,2956	TGFB1,RHOA,RAF1,AKT2,RAC1,KRAS,CYCS,APPL1,MAPK3,SMAD2,BIRC5,AXIN1,PIK3R2,MSH2,AXIN2,BCL2,MAPK1,SMAD4,MSH6
hsa05210	Colorectal cancer	0.00192325842935535	-6.25373443276451	60	19	0.0165361183637946	1149	7161	7040,387,5894,208,5879,3845,54205,26060,5595,4087,332,8312,5296,4436,8313,596,5594,4089,2956	TGFB1,RHOA,RAF1,AKT2,RAC1,KRAS,CYCS,APPL1,MAPK3,SMAD2,BIRC5,AXIN1,PIK3R2,MSH2,AXIN2,BCL2,MAPK1,SMAD4,MSH6
M00426	Survival motor neuron (SMN) complex	0.00197270114472131	-6.22835153593312	10	6	0.00522193211488251	1149	7161	25929,11218,79833,50628,11171,79760	GEMIN5,DDX20,GEMIN6,GEMIN4,STRAP,GEMIN7
hsa_M00426	Survival motor neuron (SMN) complex	0.00197270114472131	-6.22835153593312	10	6	0.00522193211488251	1149	7161	25929,11218,79833,50628,11171,79760	GEMIN5,DDX20,GEMIN6,GEMIN4,STRAP,GEMIN7
hsa_M00035	Methionine degradation	0.00197270114472131	-6.22835153593312	10	6	0.00522193211488251	1149	7161	27430,191,1788,10768,1786,4144	MAT2B,AHCY,DNMT3A,AHCYL1,DNMT1,MAT2A
M00035	Methionine degradation	0.00197270114472131	-6.22835153593312	10	6	0.00522193211488251	1149	7161	27430,191,1788,10768,1786,4144	MAT2B,AHCY,DNMT3A,AHCYL1,DNMT1,MAT2A
ko03020	RNA polymerase	0.00197607829808725	-6.22664105590341	31	12	0.010443864229765	1149	7161	5438,5436,5441,5439,5440,5433,84265,84172,30834,51728,5430,221830	POLR2I,POLR2G,POLR2L,POLR2J,POLR2K,POLR2D,POLR3GL,POLR1B,ZNRD1,POLR3K,POLR2A,TWISTNB
hsa03020	RNA polymerase	0.00197607829808725	-6.22664105590341	31	12	0.010443864229765	1149	7161	5438,5436,5441,5439,5440,5433,84265,84172,30834,51728,221830,5430	POLR2I,POLR2G,POLR2L,POLR2J,POLR2K,POLR2D,POLR3GL,POLR1B,ZNRD1,POLR3K,TWISTNB,POLR2A
hsa04150	mTOR signaling pathway	0.00209866691312687	-6.16645293909859	150	38	0.0330722367275892	1149	7161	7249,5894,6195,5562,8649,64121,84335,526,8323,5728,5296,57600,1856,81929,64223,9550,5170,9894,387,4893,54468,208,4041,3845,5605,6009,5595,7248,51382,81029,389541,79726,51719,6794,1855,528,5594,3265	TSC2,RAF1,RPS6KA1,PRKAA1,LAMTOR3,RRAGC,AKT1S1,ATP6V1B2,FZD6,PTEN,PIK3R2,FNIP2,DVL2,SEH1L,MLST8,ATP6V1G1,PDPK1,TELO2,RHOA,NRAS,MIOS,AKT2,LRP5,KRAS,MAP2K2,RHEB,MAPK3,TSC1,ATP6V1D,WNT5B,LAMTOR4,WDR59,CAB39,STK11,DVL1,ATP6V1C1,MAPK1,HRAS
ko04150	mTOR signaling pathway	0.00209866691312687	-6.16645293909859	150	38	0.0330722367275892	1149	7161	7249,5894,6195,5562,8649,64121,84335,526,8323,5728,5296,57600,1856,81929,64223,9550,5170,9894,387,4893,54468,208,4041,3845,5605,6009,5595,7248,51382,81029,389541,79726,51719,6794,1855,528,5594,3265	TSC2,RAF1,RPS6KA1,PRKAA1,LAMTOR3,RRAGC,AKT1S1,ATP6V1B2,FZD6,PTEN,PIK3R2,FNIP2,DVL2,SEH1L,MLST8,ATP6V1G1,PDPK1,TELO2,RHOA,NRAS,MIOS,AKT2,LRP5,KRAS,MAP2K2,RHEB,MAPK3,TSC1,ATP6V1D,WNT5B,LAMTOR4,WDR59,CAB39,STK11,DVL1,ATP6V1C1,MAPK1,HRAS
ko00520	Amino sugar and nucleotide sugar metabolism	0.00238273863294731	-6.03950476671827	48	16	0.0139251523063534	1149	7161	2584,55907,7360,64841,7264,10007,10020,3074,54187,51005,6675,606495,2821,51706,140838,3073	GALK1,CMAS,UGP2,GNPNAT1,TSTA3,GNPDA1,GNE,HEXB,NANS,AMDHD2,UAP1,CYB5RL,GPI,CYB5R1,NANP,HEXA
hsa00520	Amino sugar and nucleotide sugar metabolism	0.00238273863294731	-6.03950476671827	48	16	0.0139251523063534	1149	7161	55907,2584,7360,64841,7264,10007,10020,3074,54187,51005,6675,606495,2821,51706,140838,3073	CMAS,GALK1,UGP2,GNPNAT1,TSTA3,GNPDA1,GNE,HEXB,NANS,AMDHD2,UAP1,CYB5RL,GPI,CYB5R1,NANP,HEXA
hsa_M00160	V-type ATPase, eukaryotes	0.00245574628707199	-6.00932457734284	24	10	0.00870322019147084	1149	7161	533,51382,23545,535,527,528,526,8992,9114,9550	ATP6V0B,ATP6V1D,ATP6V0A2,ATP6V0A1,ATP6V0C,ATP6V1C1,ATP6V1B2,ATP6V0E1,ATP6V0D1,ATP6V1G1
M00160	V-type ATPase, eukaryotes	0.00245574628707199	-6.00932457734284	24	10	0.00870322019147084	1149	7161	533,51382,23545,535,527,528,526,8992,9114,9550	ATP6V0B,ATP6V1D,ATP6V0A2,ATP6V0A1,ATP6V0C,ATP6V1C1,ATP6V1B2,ATP6V0E1,ATP6V0D1,ATP6V1G1
hsa03030	DNA replication	0.00269574843278106	-5.91607940156883	36	13	0.0113141862489121	1149	7161	23649,6118,5111,5983,5426,5558,84153,4174,10535,4171,5982,6117,5557	POLA2,RPA2,PCNA,RFC3,POLE,PRIM2,RNASEH2C,MCM5,RNASEH2A,MCM2,RFC2,RPA1,PRIM1
ko03030	DNA replication	0.00269574843278106	-5.91607940156883	36	13	0.0113141862489121	1149	7161	6118,23649,5983,5111,5426,5558,84153,4174,10535,4171,5982,6117,5557	RPA2,POLA2,RFC3,PCNA,POLE,PRIM2,RNASEH2C,MCM5,RNASEH2A,MCM2,RFC2,RPA1,PRIM1
hsa_M00414	Bloom's syndrome complex	0.00287721535578061	-5.85093234292824	5	4	0.00348128807658834	1149	7161	641,80010,116028,7156	BLM,RMI1,RMI2,TOP3A
M00071	Glycosphingolipid biosynthesis, neolacto-series, LacCer => nLc4Cer	0.00287721535578061	-5.85093234292824	5	4	0.00348128807658834	1149	7161	2683,8703,8702,8704	B4GALT1,B4GALT3,B4GALT4,B4GALT2
hsa_M00071	Glycosphingolipid biosynthesis, neolacto-series, LacCer => nLc4Cer	0.00287721535578061	-5.85093234292824	5	4	0.00348128807658834	1149	7161	2683,8703,8702,8704	B4GALT1,B4GALT3,B4GALT4,B4GALT2
M00414	Bloom's syndrome complex	0.00287721535578061	-5.85093234292824	5	4	0.00348128807658834	1149	7161	641,80010,116028,7156	BLM,RMI1,RMI2,TOP3A
ko00510	N-Glycan biosynthesis	0.00302169270958108	-5.80193810475545	49	16	0.0139251523063534	1149	7161	8813,11253,7841,2683,4121,10195,4122,6184,1650,3703,1603,2530,6185,8703,4249,8704	DPM1,MAN1B1,MOGS,B4GALT1,MAN1A1,ALG3,MAN2A2,RPN1,DDOST,STT3A,DAD1,FUT8,RPN2,B4GALT3,MGAT5,B4GALT2
hsa00510	N-Glycan biosynthesis	0.00302169270958108	-5.80193810475545	49	16	0.0139251523063534	1149	7161	4122,10195,6184,1650,8813,3703,1603,2530,11253,7841,2683,6185,8703,4249,8704,4121	MAN2A2,ALG3,RPN1,DDOST,DPM1,STT3A,DAD1,FUT8,MAN1B1,MOGS,B4GALT1,RPN2,B4GALT3,MGAT5,B4GALT2,MAN1A1
hsa00240	Pyrimidine metabolism	0.00306618142446168	-5.78732232726892	104	28	0.0243690165361184	1149	7161	23649,5438,7083,5436,5441,5558,5440,7371,5433,6240,84265,83549,6241,1635,51728,5430,221830,5557,5426,5439,1633,1854,115024,1503,124583,139596,84172,30834	POLA2,POLR2I,TK1,POLR2G,POLR2L,PRIM2,POLR2K,UCK2,POLR2D,RRM1,POLR3GL,UCK1,RRM2,DCTD,POLR3K,POLR2A,TWISTNB,PRIM1,POLE,POLR2J,DCK,DUT,NT5C3B,CTPS1,CANT1,UPRT,POLR1B,ZNRD1
ko00240	Pyrimidine metabolism	0.00306618142446168	-5.78732232726892	104	28	0.0243690165361184	1149	7161	23649,7083,5438,5436,5441,5558,5440,5433,7371,6240,84265,83549,6241,1635,51728,5430,221830,5557,5426,5439,115024,1854,1633,1503,124583,139596,84172,30834	POLA2,TK1,POLR2I,POLR2G,POLR2L,PRIM2,POLR2K,POLR2D,UCK2,RRM1,POLR3GL,UCK1,RRM2,DCTD,POLR3K,POLR2A,TWISTNB,PRIM1,POLE,POLR2J,NT5C3B,DUT,DCK,CTPS1,CANT1,UPRT,POLR1B,ZNRD1
M00011	Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate	0.00325639637716853	-5.72713410079163	14	7	0.00609225413402959	1149	7161	8801,6390,4190,4967,8802,6389,4191	SUCLG2,SDHB,MDH1,OGDH,SUCLG1,SDHA,MDH2
M00180	RNA polymerase II, eukaryotes	0.00325639637716853	-5.72713410079163	14	7	0.00609225413402959	1149	7161	5438,5439,5436,5441,5440,5430,5433	POLR2I,POLR2J,POLR2G,POLR2L,POLR2K,POLR2A,POLR2D
hsa_M00180	RNA polymerase II, eukaryotes	0.00325639637716853	-5.72713410079163	14	7	0.00609225413402959	1149	7161	5438,5439,5436,5441,5440,5430,5433	POLR2I,POLR2J,POLR2G,POLR2L,POLR2K,POLR2A,POLR2D
hsa_M00011	Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate	0.00325639637716853	-5.72713410079163	14	7	0.00609225413402959	1149	7161	8801,6390,4190,4967,8802,6389,4191	SUCLG2,SDHB,MDH1,OGDH,SUCLG1,SDHA,MDH2
hsa01522	Endocrine resistance	0.00332786539821345	-5.70542420208947	95	26	0.0226283724978242	1149	7161	4893,208,5894,1871,3845,4853,1432,5566,5605,5595,2778,1031,5925,4193,6464,115,5296,1869,1027,596,5594,1870,3265,1029,10498,113	NRAS,AKT2,RAF1,E2F3,KRAS,NOTCH2,MAPK14,PRKACA,MAP2K2,MAPK3,GNAS,CDKN2C,RB1,MDM2,SHC1,ADCY9,PIK3R2,E2F1,CDKN1B,BCL2,MAPK1,E2F2,HRAS,CDKN2A,CARM1,ADCY7
ko01522	Endocrine resistance	0.00332786539821345	-5.70542420208947	95	26	0.0226283724978242	1149	7161	4893,208,5894,1871,3845,4853,1432,5566,5605,5595,2778,1031,5925,4193,6464,115,5296,1869,1027,596,5594,1870,3265,1029,10498,113	NRAS,AKT2,RAF1,E2F3,KRAS,NOTCH2,MAPK14,PRKACA,MAP2K2,MAPK3,GNAS,CDKN2C,RB1,MDM2,SHC1,ADCY9,PIK3R2,E2F1,CDKN1B,BCL2,MAPK1,E2F2,HRAS,CDKN2A,CARM1,ADCY7
hsa05214	Glioma	0.00434091816187131	-5.43966939521021	64	19	0.0165361183637946	1149	7161	4893,5894,208,1871,3845,5605,5595,805,5925,4193,6464,5728,5296,1869,1870,5594,3265,1029,818	NRAS,RAF1,AKT2,E2F3,KRAS,MAP2K2,MAPK3,CALM2,RB1,MDM2,SHC1,PTEN,PIK3R2,E2F1,E2F2,MAPK1,HRAS,CDKN2A,CAMK2G
ko05214	Glioma	0.00434091816187131	-5.43966939521021	64	19	0.0165361183637946	1149	7161	4893,5894,208,1871,3845,5605,5595,805,5925,4193,6464,5728,5296,1869,1870,5594,3265,1029,818	NRAS,RAF1,AKT2,E2F3,KRAS,MAP2K2,MAPK3,CALM2,RB1,MDM2,SHC1,PTEN,PIK3R2,E2F1,E2F2,MAPK1,HRAS,CDKN2A,CAMK2G
ko00020	Citrate cycle (TCA cycle)	0.00493255389030491	-5.3118983945712	30	11	0.00957354221061793	1149	7161	6390,8802,3419,4191,47,1431,8801,4190,4967,3420,6389	SDHB,SUCLG1,IDH3A,MDH2,ACLY,CS,SUCLG2,MDH1,OGDH,IDH3B,SDHA
hsa00020	Citrate cycle (TCA cycle)	0.00493255389030491	-5.3118983945712	30	11	0.00957354221061793	1149	7161	6390,8802,4191,3419,1431,47,8801,4190,4967,3420,6389	SDHB,SUCLG1,MDH2,IDH3A,CS,ACLY,SUCLG2,MDH1,OGDH,IDH3B,SDHA
M00684	JAK-STAT signaling	0.0061680206098417	-5.08837730131267	19	8	0.00696257615317668	1149	7161	3716,6778,6772,122809,9306,6774,9655,30837	JAK1,STAT6,STAT1,SOCS4,SOCS6,STAT3,SOCS5,SOCS7
hsa_M00684	JAK-STAT signaling	0.0061680206098417	-5.08837730131267	19	8	0.00696257615317668	1149	7161	3716,6778,6772,122809,9306,6774,9655,30837	JAK1,STAT6,STAT1,SOCS4,SOCS6,STAT3,SOCS5,SOCS7
ko04330	Notch signaling pathway	0.00639056962662962	-5.05293187111822	48	15	0.0130548302872063	1149	7161	9612,6868,2648,51107,23220,4242,3516,1855,4853,9794,83464,5663,1856,8650,3066	NCOR2,ADAM17,KAT2A,APH1A,DTX4,MFNG,RBPJ,DVL1,NOTCH2,MAML1,APH1B,PSEN1,DVL2,NUMB,HDAC2
hsa04330	Notch signaling pathway	0.00639056962662962	-5.05293187111822	48	15	0.0130548302872063	1149	7161	9612,6868,2648,51107,23220,4242,3516,1855,4853,9794,83464,5663,1856,8650,3066	NCOR2,ADAM17,KAT2A,APH1A,DTX4,MFNG,RBPJ,DVL1,NOTCH2,MAML1,APH1B,PSEN1,DVL2,NUMB,HDAC2
ko04966	Collecting duct acid secretion	0.00668534879022257	-5.00783689473731	27	10	0.00870322019147084	1149	7161	10723,51382,535,23545,527,528,526,8992,9114,9550	SLC12A7,ATP6V1D,ATP6V0A1,ATP6V0A2,ATP6V0C,ATP6V1C1,ATP6V1B2,ATP6V0E1,ATP6V0D1,ATP6V1G1
hsa04966	Collecting duct acid secretion	0.00668534879022257	-5.00783689473731	27	10	0.00870322019147084	1149	7161	10723,51382,535,23545,527,528,526,8992,9114,9550	SLC12A7,ATP6V1D,ATP6V0A1,ATP6V0A2,ATP6V0C,ATP6V1C1,ATP6V1B2,ATP6V0E1,ATP6V0D1,ATP6V1G1
hsa05100	Bacterial invasion of epithelial cells	0.00700484371928635	-4.96115340932264	76	21	0.0182767624020888	1149	7161	10163,391,387,10801,5879,23176,10552,10459,1399,7454,1731,6464,998,10092,9844,5296,1785,3688,55752,60,1212	WASF2,RHOG,RHOA,SEPT9,RAC1,SEPT8,ARPC1A,MAD2L2,CRKL,WAS,SEPT1,SHC1,CDC42,ARPC5,ELMO1,PIK3R2,DNM2,ITGB1,SEPT11,ACTB,CLTB
ko05100	Bacterial invasion of epithelial cells	0.00700484371928635	-4.96115340932264	76	21	0.0182767624020888	1149	7161	10163,391,387,10801,5879,23176,10552,10459,1399,7454,1731,6464,998,10092,9844,5296,1785,3688,55752,60,1212	WASF2,RHOG,RHOA,SEPT9,RAC1,SEPT8,ARPC1A,MAD2L2,CRKL,WAS,SEPT1,SHC1,CDC42,ARPC5,ELMO1,PIK3R2,DNM2,ITGB1,SEPT11,ACTB,CLTB
hsa_M00424	Shelterin complex	0.00753354319894659	-4.8883898034928	6	4	0.00348128807658834	1149	7161	54386,7013,25913,7014	TERF2IP,TERF1,POT1,TERF2
M00424	Shelterin complex	0.00753354319894659	-4.8883898034928	6	4	0.00348128807658834	1149	7161	54386,7013,25913,7014	TERF2IP,TERF1,POT1,TERF2
hsa05120	Epithelial cell signaling in Helicobacter pylori infection	0.00885142169615439	-4.72717718923084	68	19	0.0165361183637946	1149	7161	6868,102,5879,535,526,4067,1432,533,51382,998,1445,5781,23545,527,528,9020,8992,9114,9550	ADAM17,ADAM10,RAC1,ATP6V0A1,ATP6V1B2,LYN,MAPK14,ATP6V0B,ATP6V1D,CDC42,CSK,PTPN11,ATP6V0A2,ATP6V0C,ATP6V1C1,MAP3K14,ATP6V0E1,ATP6V0D1,ATP6V1G1
ko05120	Epithelial cell signaling in Helicobacter pylori infection	0.00885142169615439	-4.72717718923084	68	19	0.0165361183637946	1149	7161	6868,102,5879,535,526,4067,1432,533,51382,998,1445,5781,23545,527,528,9020,8992,9114,9550	ADAM17,ADAM10,RAC1,ATP6V0A1,ATP6V1B2,LYN,MAPK14,ATP6V0B,ATP6V1D,CDC42,CSK,PTPN11,ATP6V0A2,ATP6V0C,ATP6V1C1,MAP3K14,ATP6V0E1,ATP6V0D1,ATP6V1G1
hsa_M00352	Spliceosome, U2-snRNP	0.0088583025646976	-4.72640011683964	20	8	0.00696257615317668	1149	7161	6637,6634,23451,8175,6628,51639,11325,10992	SNRPG,SNRPD3,SF3B1,SF3A2,SNRPB,SF3B6,DDX42,SF3B2
M00352	Spliceosome, U2-snRNP	0.0088583025646976	-4.72640011683964	20	8	0.00696257615317668	1149	7161	6637,6634,23451,8175,6628,51639,11325,10992	SNRPG,SNRPD3,SF3B1,SF3A2,SNRPB,SF3B6,DDX42,SF3B2
hsa04068	FoxO signaling pathway	0.00907280527225362	-4.70247377135786	132	32	0.0278503046127067	1149	7161	5170,1263,7040,7874,5347,5564,4893,208,5894,5562,10912,3845,891,1432,2309,5605,5595,847,9456,4193,4087,5728,4616,5296,1027,6794,1017,9133,5594,6774,3265,4089	PDPK1,PLK3,TGFB1,USP7,PLK1,PRKAB1,NRAS,AKT2,RAF1,PRKAA1,GADD45G,KRAS,CCNB1,MAPK14,FOXO3,MAP2K2,MAPK3,CAT,HOMER1,MDM2,SMAD2,PTEN,GADD45B,PIK3R2,CDKN1B,STK11,CDK2,CCNB2,MAPK1,STAT3,HRAS,SMAD4
ko04370	VEGF signaling pathway	0.00936119240713183	-4.67118260268221	59	17	0.0147954743255004	1149	7161	5530,4893,7867,5894,208,5879,4773,3845,5532,1432,5605,5595,998,5296,5534,5594,3265	PPP3CA,NRAS,MAPKAPK3,RAF1,AKT2,RAC1,NFATC2,KRAS,PPP3CB,MAPK14,MAP2K2,MAPK3,CDC42,PIK3R2,PPP3R1,MAPK1,HRAS
hsa00310	Lysine degradation	0.00936119240713183	-4.67118260268221	59	17	0.0147954743255004	1149	7161	55870,55904,79813,54904,4967,2145,58508,84444,79723,84787,84193,387893,79823,9757,38,8985,223	ASH1L,KMT2E,EHMT1,NSD3,OGDH,EZH1,KMT2C,DOT1L,SUV39H2,KMT5C,SETD3,KMT5A,CAMKMT,KMT2B,ACAT1,PLOD3,ALDH9A1
ko00310	Lysine degradation	0.00936119240713183	-4.67118260268221	59	17	0.0147954743255004	1149	7161	55870,55904,79813,54904,4967,2145,58508,84444,84787,79723,84193,387893,79823,9757,38,8985,223	ASH1L,KMT2E,EHMT1,NSD3,OGDH,EZH1,KMT2C,DOT1L,KMT5C,SUV39H2,SETD3,KMT5A,CAMKMT,KMT2B,ACAT1,PLOD3,ALDH9A1
hsa04370	VEGF signaling pathway	0.00936119240713183	-4.67118260268221	59	17	0.0147954743255004	1149	7161	5530,4893,7867,5894,208,5879,4773,3845,5532,1432,5605,5595,998,5296,5534,5594,3265	PPP3CA,NRAS,MAPKAPK3,RAF1,AKT2,RAC1,NFATC2,KRAS,PPP3CB,MAPK14,MAP2K2,MAPK3,CDC42,PIK3R2,PPP3R1,MAPK1,HRAS
hsa03440	Homologous recombination	0.00945874129928398	-4.66081595981493	41	13	0.0113141862489121	1149	7161	6118,5889,9577,79728,7516,29086,7156,7517,672,641,5892,25788,6117	RPA2,RAD51C,BABAM2,PALB2,XRCC2,BABAM1,TOP3A,XRCC3,BRCA1,BLM,RAD51D,RAD54B,RPA1
ko03440	Homologous recombination	0.00945874129928398	-4.66081595981493	41	13	0.0113141862489121	1149	7161	6118,5889,9577,79728,29086,7516,7156,7517,672,641,5892,6117,25788	RPA2,RAD51C,BABAM2,PALB2,BABAM1,XRCC2,TOP3A,XRCC3,BRCA1,BLM,RAD51D,RPA1,RAD54B
hsa05213	Endometrial cancer	0.00962583835202776	-4.64330430109203	50	15	0.0130548302872063	1149	7161	5170,4893,5728,5894,8312,208,5296,8313,3845,2002,5594,3265,5605,2309,5595	PDPK1,NRAS,PTEN,RAF1,AXIN1,AKT2,PIK3R2,AXIN2,KRAS,ELK1,MAPK1,HRAS,MAP2K2,FOXO3,MAPK3
ko05213	Endometrial cancer	0.00962583835202776	-4.64330430109203	50	15	0.0130548302872063	1149	7161	5170,4893,5728,5894,8312,208,5296,8313,3845,2002,5594,3265,5605,2309,5595	PDPK1,NRAS,PTEN,RAF1,AXIN1,AKT2,PIK3R2,AXIN2,KRAS,ELK1,MAPK1,HRAS,MAP2K2,FOXO3,MAPK3
ko04137	Mitophagy - animal	0.00994326807676698	-4.61085953199122	64	18	0.0156657963446475	1149	7161	4893,79065,7879,1457,3845,598,55288,8678,89941,2309,9927,7942,10133,79735,7030,1869,10370,3265	NRAS,ATG9A,RAB7A,CSNK2A1,KRAS,BCL2L1,RHOT1,BECN1,RHOT2,FOXO3,MFN2,TFEB,OPTN,TBC1D17,TFE3,E2F1,CITED2,HRAS
hsa04137	Mitophagy - animal	0.00994326807676698	-4.61085953199122	64	18	0.0156657963446475	1149	7161	4893,79065,7879,1457,3845,598,55288,8678,89941,2309,9927,7942,10133,79735,7030,1869,10370,3265	NRAS,ATG9A,RAB7A,CSNK2A1,KRAS,BCL2L1,RHOT1,BECN1,RHOT2,FOXO3,MFN2,TFEB,OPTN,TBC1D17,TFE3,E2F1,CITED2,HRAS
hsa_M00692	Cell cycle - G1/S transition	0.010447208655137	-4.56142045059366	13	6	0.00522193211488251	1149	7161	5925,1017,1870,5933,1869,1871	RB1,CDK2,E2F2,RBL1,E2F1,E2F3
M00692	Cell cycle - G1/S transition	0.010447208655137	-4.56142045059366	13	6	0.00522193211488251	1149	7161	5925,1017,1870,5933,1869,1871	RB1,CDK2,E2F2,RBL1,E2F1,E2F3
ko04215	Apoptosis - multiple species	0.0110416847722781	-4.50607764359172	33	11	0.00957354221061793	1149	7161	578,330,332,331,596,54205,598,8678,329,27429,8772	BAK1,BIRC3,BIRC5,XIAP,BCL2,CYCS,BCL2L1,BECN1,BIRC2,HTRA2,FADD
hsa04215	Apoptosis - multiple species	0.0110416847722781	-4.50607764359172	33	11	0.00957354221061793	1149	7161	578,330,332,331,596,54205,598,8678,329,27429,8772	BAK1,BIRC3,BIRC5,XIAP,BCL2,CYCS,BCL2L1,BECN1,BIRC2,HTRA2,FADD
hsa04211	Longevity regulating pathway	0.0115742413219164	-4.45897322570084	89	23	0.0200174064403829	1149	7161	5564,4893,7249,9821,208,5562,79813,3845,84335,5566,2309,26060,6009,847,7248,115,5296,6794,9776,1385,1386,3265,113	PRKAB1,NRAS,TSC2,RB1CC1,AKT2,PRKAA1,EHMT1,KRAS,AKT1S1,PRKACA,FOXO3,APPL1,RHEB,CAT,TSC1,ADCY9,PIK3R2,STK11,ATG13,CREB1,ATF2,HRAS,ADCY7
hsa04662	B cell receptor signaling pathway	0.0122226080951819	-4.40446791960033	70	19	0.0165361183637946	1149	7161	5530,4893,5894,208,5879,7410,4773,3845,5532,4067,5605,5595,7409,4775,5296,5534,5594,975,3265	PPP3CA,NRAS,RAF1,AKT2,RAC1,VAV2,NFATC2,KRAS,PPP3CB,LYN,MAP2K2,MAPK3,VAV1,NFATC3,PIK3R2,PPP3R1,MAPK1,CD81,HRAS
ko04662	B cell receptor signaling pathway	0.0122226080951819	-4.40446791960033	70	19	0.0165361183637946	1149	7161	5530,4893,5894,208,5879,7410,4773,3845,5532,4067,5605,5595,7409,4775,5296,5534,5594,975,3265	PPP3CA,NRAS,RAF1,AKT2,RAC1,VAV2,NFATC2,KRAS,PPP3CB,LYN,MAP2K2,MAPK3,VAV1,NFATC3,PIK3R2,PPP3R1,MAPK1,CD81,HRAS
hsa_M00351	Spliceosome, U1-snRNP	0.0131049235237898	-4.33476727787508	10	5	0.00435161009573542	1149	7161	6637,6634,6625,6628,6626	SNRPG,SNRPD3,SNRNP70,SNRPB,SNRPA
M00351	Spliceosome, U1-snRNP	0.0131049235237898	-4.33476727787508	10	5	0.00435161009573542	1149	7161	6637,6634,6625,6628,6626	SNRPG,SNRPD3,SNRNP70,SNRPB,SNRPA
M00401	Sec61 complex	0.0145074708686764	-4.2330915299197	4	3	0.00261096605744125	1149	7161	10952,29927,23480	SEC61B,SEC61A1,SEC61G
M00261	DNA polymerase alpha / primase complex	0.0145074708686764	-4.2330915299197	4	3	0.00261096605744125	1149	7161	23649,5558,5557	POLA2,PRIM2,PRIM1
hsa_M00261	DNA polymerase alpha / primase complex	0.0145074708686764	-4.2330915299197	4	3	0.00261096605744125	1149	7161	23649,5558,5557	POLA2,PRIM2,PRIM1
hsa_M00401	Sec61 complex	0.0145074708686764	-4.2330915299197	4	3	0.00261096605744125	1149	7161	10952,29927,23480	SEC61B,SEC61A1,SEC61G
M00389	APC/C complex	0.0158403178635263	-4.14519682565539	14	6	0.00522193211488251	1149	7161	29882,51434,8881,8697,996,29945	ANAPC2,ANAPC7,CDC16,CDC23,CDC27,ANAPC4
ko00533	Glycosaminoglycan biosynthesis - keratan sulfate	0.0158403178635263	-4.14519682565539	14	6	0.00522193211488251	1149	7161	2683,6483,8703,8702,2530,8704	B4GALT1,ST3GAL2,B4GALT3,B4GALT4,FUT8,B4GALT2
hsa_M00389	APC/C complex	0.0158403178635263	-4.14519682565539	14	6	0.00522193211488251	1149	7161	29882,51434,8881,8697,996,29945	ANAPC2,ANAPC7,CDC16,CDC23,CDC27,ANAPC4
hsa00533	Glycosaminoglycan biosynthesis - keratan sulfate	0.0158403178635263	-4.14519682565539	14	6	0.00522193211488251	1149	7161	2683,6483,8702,8703,2530,8704	B4GALT1,ST3GAL2,B4GALT4,B4GALT3,FUT8,B4GALT2
ko00514	Other types of O-glycan biosynthesis	0.0167186476714157	-4.09123055549281	22	8	0.00696257615317668	1149	7161	283464,4242,8473,2683,8703,8985,23509,8704	GXYLT1,MFNG,OGT,B4GALT1,B4GALT3,PLOD3,POFUT1,B4GALT2
hsa00514	Other types of O-glycan biosynthesis	0.0167186476714157	-4.09123055549281	22	8	0.00696257615317668	1149	7161	283464,4242,8473,2683,8703,8985,23509,8704	GXYLT1,MFNG,OGT,B4GALT1,B4GALT3,PLOD3,POFUT1,B4GALT2
hsa05203	Viral carcinogenesis	0.0167779801519184	-4.0876879575413	201	44	0.0382941688424717	1149	7161	7874,3133,5879,3661,27044,5566,4067,3105,5925,4193,890,6672,998,51564,3572,5296,1027,1385,1386,6774,2966,9114,578,4893,387,2648,3845,5315,5595,3106,3716,5933,9519,7534,3516,1017,7533,5594,7188,5700,3265,1642,1029,3066	USP7,HLA-E,RAC1,IRF3,SND1,PRKACA,LYN,HLA-A,RB1,MDM2,CCNA2,SP100,CDC42,HDAC7,IL6ST,PIK3R2,CDKN1B,CREB1,ATF2,STAT3,GTF2H2,ATP6V0D1,BAK1,NRAS,RHOA,KAT2A,KRAS,PKM,MAPK3,HLA-B,JAK1,RBL1,TBPL1,YWHAZ,RBPJ,CDK2,YWHAH,MAPK1,TRAF5,PSMC1,HRAS,DDB1,CDKN2A,HDAC2
ko05203	Viral carcinogenesis	0.0167779801519184	-4.0876879575413	201	44	0.0382941688424717	1149	7161	7874,3133,5879,3661,27044,5566,4067,3105,5925,4193,890,6672,998,51564,3572,5296,1027,1385,1386,6774,2966,9114,578,4893,387,2648,3845,5315,5595,3106,3716,5933,9519,7534,3516,1017,7533,5594,7188,5700,3265,1642,1029,3066	USP7,HLA-E,RAC1,IRF3,SND1,PRKACA,LYN,HLA-A,RB1,MDM2,CCNA2,SP100,CDC42,HDAC7,IL6ST,PIK3R2,CDKN1B,CREB1,ATF2,STAT3,GTF2H2,ATP6V0D1,BAK1,NRAS,RHOA,KAT2A,KRAS,PKM,MAPK3,HLA-B,JAK1,RBL1,TBPL1,YWHAZ,RBPJ,CDK2,YWHAH,MAPK1,TRAF5,PSMC1,HRAS,DDB1,CDKN2A,HDAC2
M00430	Exon junction complex (EJC)	0.0167942499700606	-4.08671871484537	18	7	0.00609225413402959	1149	7161	26019,5976,29107,9775,9939,10921,55916	UPF2,UPF1,NXT1,EIF4A3,RBM8A,RNPS1,NXT2
hsa_M00430	Exon junction complex (EJC)	0.0167942499700606	-4.08671871484537	18	7	0.00609225413402959	1149	7161	26019,5976,29107,9775,9939,10921,55916	UPF2,UPF1,NXT1,EIF4A3,RBM8A,RNPS1,NXT2
ko04962	Vasopressin-regulated water reabsorption	0.0175446585487663	-4.04300573159166	44	13	0.0113141862489121	1149	7161	2778,4905,9230,8655,10540,115,397,1385,5566,5869,8766,1783,1639	GNAS,NSF,RAB11B,DYNLL1,DCTN2,ADCY9,ARHGDIB,CREB1,PRKACA,RAB5B,RAB11A,DYNC1LI2,DCTN1
hsa04962	Vasopressin-regulated water reabsorption	0.0175446585487663	-4.04300573159166	44	13	0.0113141862489121	1149	7161	2778,4905,9230,8655,10540,115,397,1385,5566,5869,8766,1783,1639	GNAS,NSF,RAB11B,DYNLL1,DCTN2,ADCY9,ARHGDIB,CREB1,PRKACA,RAB5B,RAB11A,DYNC1LI2,DCTN1
hsa04710	Circadian rhythm	0.0191864088443115	-3.95355312330068	31	10	0.00870322019147084	1149	7161	6096,5564,9978,406,5562,8454,1408,26224,1385,1453	RORB,PRKAB1,RBX1,ARNTL,PRKAA1,CUL1,CRY2,FBXL3,CREB1,CSNK1D
ko04710	Circadian rhythm	0.0191864088443115	-3.95355312330068	31	10	0.00870322019147084	1149	7161	6096,5564,9978,406,5562,8454,1408,26224,1385,1453	RORB,PRKAB1,RBX1,ARNTL,PRKAA1,CUL1,CRY2,FBXL3,CREB1,CSNK1D
ko04216	Ferroptosis	0.0195525896686456	-3.93464753745398	40	12	0.010443864229765	1149	7161	51703,2512,2730,2181,7417,5093,81631,112483,5094,7037,2879,5621	ACSL5,FTL,GCLM,ACSL3,VDAC2,PCBP1,MAP1LC3B,SAT2,PCBP2,TFRC,GPX4,PRNP
hsa04216	Ferroptosis	0.0195525896686456	-3.93464753745398	40	12	0.010443864229765	1149	7161	51703,2512,2730,2181,7417,5093,81631,112483,5094,7037,2879,5621	ACSL5,FTL,GCLM,ACSL3,VDAC2,PCBP1,MAP1LC3B,SAT2,PCBP2,TFRC,GPX4,PRNP
ko04722	Neurotrophin signaling pathway	0.0207352573987305	-3.87591977162897	119	28	0.0243690165361184	1149	7161	5170,387,4893,5894,6195,208,5879,9500,3845,397,1432,5663,2309,5605,5595,805,1399,5906,998,6464,5296,11108,5781,596,4217,5594,3265,818	PDPK1,RHOA,NRAS,RAF1,RPS6KA1,AKT2,RAC1,MAGED1,KRAS,ARHGDIB,MAPK14,PSEN1,FOXO3,MAP2K2,MAPK3,CALM2,CRKL,RAP1A,CDC42,SHC1,PIK3R2,PRDM4,PTPN11,BCL2,MAP3K5,MAPK1,HRAS,CAMK2G
hsa04722	Neurotrophin signaling pathway	0.0207352573987305	-3.87591977162897	119	28	0.0243690165361184	1149	7161	5170,387,4893,5894,6195,208,5879,9500,3845,397,1432,5663,2309,5605,5595,805,1399,5906,998,6464,5296,11108,5781,596,4217,5594,3265,818	PDPK1,RHOA,NRAS,RAF1,RPS6KA1,AKT2,RAC1,MAGED1,KRAS,ARHGDIB,MAPK14,PSEN1,FOXO3,MAP2K2,MAPK3,CALM2,CRKL,RAP1A,CDC42,SHC1,PIK3R2,PRDM4,PTPN11,BCL2,MAP3K5,MAPK1,HRAS,CAMK2G
hsa_M00034	Methionine salvage pathway	0.0208976867542958	-3.86811680774968	11	5	0.00435161009573542	1149	7161	27430,6723,84245,262,4144	MAT2B,SRM,MRI1,AMD1,MAT2A
M00034	Methionine salvage pathway	0.0208976867542958	-3.86811680774968	11	5	0.00435161009573542	1149	7161	27430,6723,84245,262,4144	MAT2B,SRM,MRI1,AMD1,MAT2A
hsa03050	Proteasome	0.021156476676818	-3.85580919451314	45	13	0.0113141862489121	1149	7161	5708,5687,5707,143471,5709,5714,5695,5682,51371,5698,5700,5691,5704	PSMD2,PSMA6,PSMD1,PSMA8,PSMD3,PSMD8,PSMB7,PSMA1,POMP,PSMB9,PSMC1,PSMB3,PSMC4
ko03050	Proteasome	0.021156476676818	-3.85580919451314	45	13	0.0113141862489121	1149	7161	5708,5687,5707,143471,5709,5714,5695,5682,51371,5698,5700,5691,5704	PSMD2,PSMA6,PSMD1,PSMA8,PSMD3,PSMD8,PSMB7,PSMA1,POMP,PSMB9,PSMC1,PSMB3,PSMC4
hsa04115	p53 signaling pathway	0.0216776079223356	-3.83147544418375	69	18	0.0156657963446475	1149	7161	7249,10912,6241,92344,54205,891,355,4193,6477,5728,4616,9538,51512,11200,1017,9133,64393,1029	TSC2,GADD45G,RRM2,GORAB,CYCS,CCNB1,FAS,MDM2,SIAH1,PTEN,GADD45B,EI24,GTSE1,CHEK2,CDK2,CCNB2,ZMAT3,CDKN2A
ko04115	p53 signaling pathway	0.0216776079223356	-3.83147544418375	69	18	0.0156657963446475	1149	7161	7249,10912,6241,92344,54205,891,355,4193,6477,5728,4616,9538,51512,11200,1017,9133,64393,1029	TSC2,GADD45G,RRM2,GORAB,CYCS,CCNB1,FAS,MDM2,SIAH1,PTEN,GADD45B,EI24,GTSE1,CHEK2,CDK2,CCNB2,ZMAT3,CDKN2A
ko03430	Mismatch repair	0.0221193354359614	-3.81130314636153	23	8	0.00696257615317668	1149	7161	6118,5983,5111,5395,4436,5982,2956,6117	RPA2,RFC3,PCNA,PMS2,MSH2,RFC2,MSH6,RPA1
hsa03430	Mismatch repair	0.0221193354359614	-3.81130314636153	23	8	0.00696257615317668	1149	7161	6118,5111,5983,5395,4436,5982,2956,6117	RPA2,PCNA,RFC3,PMS2,MSH2,RFC2,MSH6,RPA1
hsa_M00146	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex	0.0228879242815817	-3.77714583145451	15	6	0.00522193211488251	1149	7161	4697,4698,4701,4695,4696,126328	NDUFA4,NDUFA5,NDUFA7,NDUFA2,NDUFA3,NDUFA11
M00146	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex	0.0228879242815817	-3.77714583145451	15	6	0.00522193211488251	1149	7161	4697,4698,4701,4695,4696,126328	NDUFA4,NDUFA5,NDUFA7,NDUFA2,NDUFA3,NDUFA11
ko04136	Autophagy - other	0.0240093790168897	-3.72931073260324	32	10	0.00870322019147084	1149	7161	5515,79065,64422,55102,9776,26100,8678,3476,115201,64223	PPP2CA,ATG9A,ATG3,ATG2B,ATG13,WIPI2,BECN1,IGBP1,ATG4A,MLST8
hsa04136	Autophagy - other	0.0240093790168897	-3.72931073260324	32	10	0.00870322019147084	1149	7161	5515,79065,64422,55102,9776,26100,8678,3476,115201,64223	PPP2CA,ATG9A,ATG3,ATG2B,ATG13,WIPI2,BECN1,IGBP1,ATG4A,MLST8
ko04145	Phagosome	0.0243344187352878	-3.71586352193688	152	34	0.0295909486510009	1149	7161	23480,3133,5879,6890,526,3693,7037,3105,533,1520,23545,6891,11151,200576,9114,9550,10952,7879,535,5869,1514,3106,51382,9146,29927,53407,3688,527,60,949,528,8992,203068,1783	SEC61G,HLA-E,RAC1,TAP1,ATP6V1B2,ITGB5,TFRC,HLA-A,ATP6V0B,CTSS,ATP6V0A2,TAP2,CORO1A,PIKFYVE,ATP6V0D1,ATP6V1G1,SEC61B,RAB7A,ATP6V0A1,RAB5B,CTSL,HLA-B,ATP6V1D,HGS,SEC61A1,STX18,ITGB1,ATP6V0C,ACTB,SCARB1,ATP6V1C1,ATP6V0E1,TUBB,DYNC1LI2
hsa04145	Phagosome	0.0243344187352878	-3.71586352193688	152	34	0.0295909486510009	1149	7161	23480,3133,5879,6890,526,3693,7037,3105,533,1520,23545,6891,11151,200576,9114,9550,10952,7879,535,5869,1514,3106,51382,9146,29927,53407,3688,527,60,949,528,8992,203068,1783	SEC61G,HLA-E,RAC1,TAP1,ATP6V1B2,ITGB5,TFRC,HLA-A,ATP6V0B,CTSS,ATP6V0A2,TAP2,CORO1A,PIKFYVE,ATP6V0D1,ATP6V1G1,SEC61B,RAB7A,ATP6V0A1,RAB5B,CTSL,HLA-B,ATP6V1D,HGS,SEC61A1,STX18,ITGB1,ATP6V0C,ACTB,SCARB1,ATP6V1C1,ATP6V0E1,TUBB,DYNC1LI2
ko05230	Central carbon metabolism in cancer	0.0246172459297088	-3.70430802761422	65	17	0.0147954743255004	1149	7161	2261,4893,57103,5728,208,5894,5296,6513,3939,3845,5315,5223,5594,5605,3265,5214,5595	FGFR3,NRAS,TIGAR,PTEN,AKT2,RAF1,PIK3R2,SLC2A1,LDHA,KRAS,PKM,PGAM1,MAPK1,MAP2K2,HRAS,PFKP,MAPK3
hsa05230	Central carbon metabolism in cancer	0.0246172459297088	-3.70430802761422	65	17	0.0147954743255004	1149	7161	2261,4893,57103,5728,208,5894,5296,6513,3939,3845,5315,5223,5594,5605,3265,5214,5595	FGFR3,NRAS,TIGAR,PTEN,AKT2,RAF1,PIK3R2,SLC2A1,LDHA,KRAS,PKM,PGAM1,MAPK1,MAP2K2,HRAS,PFKP,MAPK3
hsa04917	Prolactin signaling pathway	0.0249504924776288	-3.6908617183971	70	18	0.0156657963446475	1149	7161	4893,208,5894,3845,1432,2309,5605,5595,30837,6464,5296,9306,122809,6772,6774,5594,3265,9655	NRAS,AKT2,RAF1,KRAS,MAPK14,FOXO3,MAP2K2,MAPK3,SOCS7,SHC1,PIK3R2,SOCS6,SOCS4,STAT1,STAT3,MAPK1,HRAS,SOCS5
ko04917	Prolactin signaling pathway	0.0249504924776288	-3.6908617183971	70	18	0.0156657963446475	1149	7161	4893,208,5894,3845,1432,2309,5605,5595,30837,6464,5296,9306,122809,6772,6774,5594,3265,9655	NRAS,AKT2,RAF1,KRAS,MAPK14,FOXO3,MAP2K2,MAPK3,SOCS7,SHC1,PIK3R2,SOCS6,SOCS4,STAT1,STAT3,MAPK1,HRAS,SOCS5
hsa04919	Thyroid hormone signaling pathway	0.0260734732955545	-3.64683683031551	116	27	0.0234986945169713	1149	7161	5170,4893,2648,7249,208,5894,6513,23389,3845,4853,5566,5605,6009,5595,6257,476,4193,488,5296,6772,60,8648,5594,3265,10499,3066,5214	PDPK1,NRAS,KAT2A,TSC2,AKT2,RAF1,SLC2A1,MED13L,KRAS,NOTCH2,PRKACA,MAP2K2,RHEB,MAPK3,RXRB,ATP1A1,MDM2,ATP2A2,PIK3R2,STAT1,ACTB,NCOA1,MAPK1,HRAS,NCOA2,HDAC2,PFKP
ko05168	Herpes simplex infection	0.0263663322847225	-3.63566737495241	185	40	0.0348128807658834	1149	7161	23586,7874,3133,6431,6890,1457,8454,54205,3661,10629,440275,3105,112950,6672,6429,5781,6891,27097,57506,1936,3150,27102,6430,5430,8772,6426,355,3106,3716,23118,406,6772,5371,9519,148022,6428,6041,6878,7188,1017	DDX58,USP7,HLA-E,SRSF6,TAP1,CSNK2A1,CUL1,CYCS,IRF3,TAF6L,EIF2AK4,HLA-A,MED8,SP100,SRSF4,PTPN11,TAP2,TAF5L,MAVS,EEF1D,HMGN1,EIF2AK1,SRSF5,POLR2A,FADD,SRSF1,FAS,HLA-B,JAK1,TAB2,ARNTL,STAT1,PML,TBPL1,TICAM1,SRSF3,RNASEL,TAF6,TRAF5,CDK2
hsa05168	Herpes simplex infection	0.0263663322847225	-3.63566737495241	185	40	0.0348128807658834	1149	7161	23586,7874,3133,6431,6890,1457,8454,54205,3661,10629,440275,3105,112950,6672,6429,5781,6891,27097,57506,1936,3150,27102,6430,5430,8772,6426,355,3106,3716,23118,406,6772,5371,9519,148022,6428,6041,6878,7188,1017	DDX58,USP7,HLA-E,SRSF6,TAP1,CSNK2A1,CUL1,CYCS,IRF3,TAF6L,EIF2AK4,HLA-A,MED8,SP100,SRSF4,PTPN11,TAP2,TAF5L,MAVS,EEF1D,HMGN1,EIF2AK1,SRSF5,POLR2A,FADD,SRSF1,FAS,HLA-B,JAK1,TAB2,ARNTL,STAT1,PML,TBPL1,TICAM1,SRSF3,RNASEL,TAF6,TRAF5,CDK2
hsa_M00687	MAPK (ERK1/2) signaling	0.0268541093880515	-3.61733641990387	8	4	0.00348128807658834	1149	7161	5594,5894,5605,5595	MAPK1,RAF1,MAP2K2,MAPK3
M00687	MAPK (ERK1/2) signaling	0.0268541093880515	-3.61733641990387	8	4	0.00348128807658834	1149	7161	5594,5894,5605,5595	MAPK1,RAF1,MAP2K2,MAPK3
hsa04340	Hedgehog signaling pathway	0.0300011005617475	-3.50652121260129	47	13	0.0113141862489121	1149	7161	1455,156,53944,8452,8454,596,1452,57154,409,5566,1453,1456,132884	CSNK1G2,GRK2,CSNK1G1,CUL3,CUL1,BCL2,CSNK1A1,SMURF1,ARRB2,PRKACA,CSNK1D,CSNK1G3,EVC2
ko04340	Hedgehog signaling pathway	0.0300011005617475	-3.50652121260129	47	13	0.0113141862489121	1149	7161	1455,156,53944,8452,8454,596,1452,57154,409,5566,1453,1456,132884	CSNK1G2,GRK2,CSNK1G1,CUL3,CUL1,BCL2,CSNK1A1,SMURF1,ARRB2,PRKACA,CSNK1D,CSNK1G3,EVC2
hsa03420	Nucleotide excision repair	0.0300011005617475	-3.50652121260129	47	13	0.0113141862489121	1149	7161	6118,2067,5111,5983,5426,9978,7507,5887,5982,2966,1642,5886,6117	RPA2,ERCC1,PCNA,RFC3,POLE,RBX1,XPA,RAD23B,RFC2,GTF2H2,DDB1,RAD23A,RPA1
ko03420	Nucleotide excision repair	0.0300011005617475	-3.50652121260129	47	13	0.0113141862489121	1149	7161	6118,2067,5983,5111,5426,9978,7507,5887,2966,5982,1642,6117,5886	RPA2,ERCC1,RFC3,PCNA,POLE,RBX1,XPA,RAD23B,GTF2H2,RFC2,DDB1,RPA1,RAD23A
hsa_M00182	RNA polymerase I, eukaryotes	0.0311841342187238	-3.4678458321368	12	5	0.00435161009573542	1149	7161	84172,5441,5440,30834,221830	POLR1B,POLR2L,POLR2K,ZNRD1,TWISTNB
M00412	ESCRT-III complex	0.0311841342187238	-3.4678458321368	12	5	0.00435161009573542	1149	7161	27243,128866,29082,25978,91782	CHMP2A,CHMP4B,CHMP4A,CHMP2B,CHMP7
M00182	RNA polymerase I, eukaryotes	0.0311841342187238	-3.4678458321368	12	5	0.00435161009573542	1149	7161	84172,5441,5440,30834,221830	POLR1B,POLR2L,POLR2K,ZNRD1,TWISTNB
hsa_M00412	ESCRT-III complex	0.0311841342187238	-3.4678458321368	12	5	0.00435161009573542	1149	7161	27243,128866,29082,25978,91782	CHMP2A,CHMP4B,CHMP4A,CHMP2B,CHMP7
M00682	Notch signaling	0.0317684409328962	-3.44928190546809	16	6	0.00522193211488251	1149	7161	6868,4853,3516,5663,51107,83464	ADAM17,NOTCH2,RBPJ,PSEN1,APH1A,APH1B
M00075	N-glycan biosynthesis, complex type	0.0317684409328962	-3.44928190546809	16	6	0.00522193211488251	1149	7161	4122,2683,8703,4249,2530,8704	MAN2A2,B4GALT1,B4GALT3,MGAT5,FUT8,B4GALT2
hsa_M00075	N-glycan biosynthesis, complex type	0.0317684409328962	-3.44928190546809	16	6	0.00522193211488251	1149	7161	4122,2683,8703,4249,2530,8704	MAN2A2,B4GALT1,B4GALT3,MGAT5,FUT8,B4GALT2
hsa_M00682	Notch signaling	0.0317684409328962	-3.44928190546809	16	6	0.00522193211488251	1149	7161	6868,4853,3516,5663,51107,83464	ADAM17,NOTCH2,RBPJ,PSEN1,APH1A,APH1B
M00079	Keratan sulfate degradation	0.0319528541384266	-3.44349377074225	5	3	0.00261096605744125	1149	7161	2799,3073,3074	GNS,HEXA,HEXB
hsa_M00079	Keratan sulfate degradation	0.0319528541384266	-3.44349377074225	5	3	0.00261096605744125	1149	7161	2799,3073,3074	GNS,HEXA,HEXB
ko03018	RNA degradation	0.0325139671862558	-3.42608552238954	77	19	0.0165361183637946	1149	7161	118460,7832,51691,5393,5073,219988,8761,4849,80153,9125,23016,11157,51013,55802,57472,246175,26986,10140,5214	EXOSC6,BTG2,LSM8,EXOSC9,PARN,PATL1,PABPC4,CNOT3,EDC3,CNOT9,EXOSC7,LSM6,EXOSC1,DCP1A,CNOT6,CNOT6L,PABPC1,TOB1,PFKP
hsa03018	RNA degradation	0.0325139671862558	-3.42608552238954	77	19	0.0165361183637946	1149	7161	118460,7832,51691,5393,5073,219988,8761,4849,80153,9125,23016,11157,51013,55802,57472,246175,26986,10140,5214	EXOSC6,BTG2,LSM8,EXOSC9,PARN,PATL1,PABPC4,CNOT3,EDC3,CNOT9,EXOSC7,LSM6,EXOSC1,DCP1A,CNOT6,CNOT6L,PABPC1,TOB1,PFKP
ko05216	Thyroid cancer	0.0329494172640095	-3.41278170365254	29	9	0.00783289817232376	1149	7161	4893,8030,3845,10342,5594,3265,5605,6257,5595	NRAS,CCDC6,KRAS,TFG,MAPK1,HRAS,MAP2K2,RXRB,MAPK3
hsa05216	Thyroid cancer	0.0329494172640095	-3.41278170365254	29	9	0.00783289817232376	1149	7161	4893,8030,3845,10342,5594,3265,5605,6257,5595	NRAS,CCDC6,KRAS,TFG,MAPK1,HRAS,MAP2K2,RXRB,MAPK3
ko00230	Purine metabolism	0.0369226993607989	-3.29892875823905	173	37	0.0322019147084421	1149	7161	23649,51816,5440,6240,51728,2618,471,115,84172,30834,113,22875,271,84284,5438,5558,5441,5436,2987,5433,158,6241,84265,5315,5140,5430,221830,5557,159,5426,5439,1633,115024,2983,5634,3614,124583	POLA2,ADA2,POLR2K,RRM1,POLR3K,GART,ATIC,ADCY9,POLR1B,ZNRD1,ADCY7,ENPP4,AMPD2,NTPCR,POLR2I,PRIM2,POLR2L,POLR2G,GUK1,POLR2D,ADSL,RRM2,POLR3GL,PKM,PDE3B,POLR2A,TWISTNB,PRIM1,ADSS,POLE,POLR2J,DCK,NT5C3B,GUCY1B1,PRPS2,IMPDH1,CANT1
hsa00230	Purine metabolism	0.0369226993607989	-3.29892875823905	173	37	0.0322019147084421	1149	7161	23649,51816,5440,6240,51728,2618,471,115,84172,30834,113,22875,271,84284,5438,5558,5441,2987,5436,5433,84265,158,6241,5315,5140,221830,5430,5557,159,5439,5426,1633,115024,2983,5634,3614,124583	POLA2,ADA2,POLR2K,RRM1,POLR3K,GART,ATIC,ADCY9,POLR1B,ZNRD1,ADCY7,ENPP4,AMPD2,NTPCR,POLR2I,PRIM2,POLR2L,GUK1,POLR2G,POLR2D,POLR3GL,ADSL,RRM2,PKM,PDE3B,TWISTNB,POLR2A,PRIM1,ADSS,POLR2J,POLE,DCK,NT5C3B,GUCY1B1,PRPS2,IMPDH1,CANT1
ko04721	Synaptic vesicle cycle	0.0370647772194528	-3.29508816142834	63	16	0.0139251523063534	1149	7161	535,526,533,51382,4905,1785,163,23545,527,1212,528,9114,8992,440279,1175,9550	ATP6V0A1,ATP6V1B2,ATP6V0B,ATP6V1D,NSF,DNM2,AP2B1,ATP6V0A2,ATP6V0C,CLTB,ATP6V1C1,ATP6V0D1,ATP6V0E1,UNC13C,AP2S1,ATP6V1G1
hsa04721	Synaptic vesicle cycle	0.0370647772194528	-3.29508816142834	63	16	0.0139251523063534	1149	7161	535,526,533,51382,4905,1785,163,23545,527,1212,528,9114,8992,440279,1175,9550	ATP6V0A1,ATP6V1B2,ATP6V0B,ATP6V1D,NSF,DNM2,AP2B1,ATP6V0A2,ATP6V0C,CLTB,ATP6V1C1,ATP6V0D1,ATP6V0E1,UNC13C,AP2S1,ATP6V1G1
hsa00970	Aminoacyl-tRNA biosynthesis	0.0401526705244489	-3.2150663271164	44	12	0.010443864229765	1149	7161	2193,51520,3735,2058,3376,283459,3035,5859,55699,55278,6897,79587	FARSA,LARS,KARS,EPRS,IARS,GATC,HARS,QARS,IARS2,QRSL1,TARS,CARS2
ko00970	Aminoacyl-tRNA biosynthesis	0.0401526705244489	-3.2150663271164	44	12	0.010443864229765	1149	7161	2193,3735,2058,51520,283459,3376,3035,5859,55699,55278,6897,79587	FARSA,KARS,EPRS,LARS,GATC,IARS,HARS,QARS,IARS2,QRSL1,TARS,CARS2
hsa05222	Small cell lung cancer	0.040818018811195	-3.19863165753588	84	20	0.0174064403829417	1149	7161	4149,330,208,1871,331,54205,598,329,6257,5925,5728,5296,1869,3688,9063,1027,596,1870,7188,1017	MAX,BIRC3,AKT2,E2F3,XIAP,CYCS,BCL2L1,BIRC2,RXRB,RB1,PTEN,PIK3R2,E2F1,ITGB1,PIAS2,CDKN1B,BCL2,E2F2,TRAF5,CDK2
ko05222	Small cell lung cancer	0.040818018811195	-3.19863165753588	84	20	0.0174064403829417	1149	7161	4149,330,208,1871,331,54205,598,329,6257,5925,5728,5296,1869,3688,9063,1027,596,1870,7188,1017	MAX,BIRC3,AKT2,E2F3,XIAP,CYCS,BCL2L1,BIRC2,RXRB,RB1,PTEN,PIK3R2,E2F1,ITGB1,PIAS2,CDKN1B,BCL2,E2F2,TRAF5,CDK2
hsa05131	Shigellosis	0.0423359825163113	-3.16211790402418	64	16	0.0139251523063534	1149	7161	10163,391,5879,10552,1432,10459,5595,1399,7454,998,10092,9844,3688,60,6093,5594	WASF2,RHOG,RAC1,ARPC1A,MAPK14,MAD2L2,MAPK3,CRKL,WAS,CDC42,ARPC5,ELMO1,ITGB1,ACTB,ROCK1,MAPK1
ko04666	Fc gamma R-mediated phagocytosis	0.0447674149295294	-3.10627474952815	90	21	0.0182767624020888	1149	7161	10163,5894,208,5879,7410,4067,10552,5595,23396,7409,1399,8853,7454,7408,998,10092,3984,5296,1785,5594,1072	WASF2,RAF1,AKT2,RAC1,VAV2,LYN,ARPC1A,MAPK3,PIP5K1C,VAV1,CRKL,ASAP2,WAS,VASP,CDC42,ARPC5,LIMK1,PIK3R2,DNM2,MAPK1,CFL1
hsa04666	Fc gamma R-mediated phagocytosis	0.0447674149295294	-3.10627474952815	90	21	0.0182767624020888	1149	7161	10163,5894,208,5879,7410,4067,10552,5595,23396,7409,1399,8853,7454,7408,998,10092,3984,5296,1785,5594,1072	WASF2,RAF1,AKT2,RAC1,VAV2,LYN,ARPC1A,MAPK3,PIP5K1C,VAV1,CRKL,ASAP2,WAS,VASP,CDC42,ARPC5,LIMK1,PIK3R2,DNM2,MAPK1,CFL1
hsa05200	Pathways in cancer	0.046006142464064	-3.07898035958014	395	76	0.0661444734551784	1149	7161	4149,5894,6513,5879,331,598,5566,329,2783,1399,4193,998,5899,5296,115,1027,10342,2149,1856,113,4893,330,9978,7428,208,2788,1871,4087,3716,8312,6772,3688,1855,6093,5594,1870,7188,4089,3066,54205,2113,8323,2261,5925,5728,9138,1612,4436,8313,596,6774,2771,2956,7040,387,23365,3845,5605,26060,8772,1613,5595,355,6257,2778,2768,332,8030,81029,1869,9063,5371,1017,3265,1029,54583	MAX,RAF1,SLC2A1,RAC1,XIAP,BCL2L1,PRKACA,BIRC2,GNB2,CRKL,MDM2,CDC42,RALB,PIK3R2,ADCY9,CDKN1B,TFG,F2R,DVL2,ADCY7,NRAS,BIRC3,RBX1,VHL,AKT2,GNG7,E2F3,SMAD2,JAK1,AXIN1,STAT1,ITGB1,DVL1,ROCK1,MAPK1,E2F2,TRAF5,SMAD4,HDAC2,CYCS,ETS1,FZD6,FGFR3,RB1,PTEN,ARHGEF1,DAPK1,MSH2,AXIN2,BCL2,STAT3,GNAI2,MSH6,TGFB1,RHOA,ARHGEF12,KRAS,MAP2K2,APPL1,FADD,DAPK3,MAPK3,FAS,RXRB,GNAS,GNA12,BIRC5,CCDC6,WNT5B,E2F1,PIAS2,PML,CDK2,HRAS,CDKN2A,EGLN1
ko00900	Terpenoid backbone biosynthesis	0.0504800399238018	-2.98617726986594	22	7	0.00609225413402959	1149	7161	38,2339,116150,23463,10654,9453,57107	ACAT1,FNTA,NUS1,ICMT,PMVK,GGPS1,PDSS2
hsa00900	Terpenoid backbone biosynthesis	0.0504800399238018	-2.98617726986594	22	7	0.00609225413402959	1149	7161	38,116150,2339,23463,9453,10654,57107	ACAT1,NUS1,FNTA,ICMT,GGPS1,PMVK,PDSS2
ko04071	Sphingolipid signaling pathway	0.0525895588577995	-2.94523767974466	118	26	0.0226283724978242	1149	7161	5170,387,4893,208,5894,5879,427,3845,9294,1432,5605,5595,5515,2768,5525,5728,253782,5296,596,6093,4217,5594,2771,55844,3265,4363	PDPK1,RHOA,NRAS,AKT2,RAF1,RAC1,ASAH1,KRAS,S1PR2,MAPK14,MAP2K2,MAPK3,PPP2CA,GNA12,PPP2R5A,PTEN,CERS6,PIK3R2,BCL2,ROCK1,MAP3K5,MAPK1,GNAI2,PPP2R2D,HRAS,ABCC1
hsa04071	Sphingolipid signaling pathway	0.0525895588577995	-2.94523767974466	118	26	0.0226283724978242	1149	7161	5170,387,4893,208,5894,5879,427,3845,9294,1432,5605,5595,5515,2768,5525,5728,253782,5296,596,6093,4217,5594,2771,55844,3265,4363	PDPK1,RHOA,NRAS,AKT2,RAF1,RAC1,ASAH1,KRAS,S1PR2,MAPK14,MAP2K2,MAPK3,PPP2CA,GNA12,PPP2R5A,PTEN,CERS6,PIK3R2,BCL2,ROCK1,MAP3K5,MAPK1,GNAI2,PPP2R2D,HRAS,ABCC1
hsa05014	Amyotrophic lateral sclerosis (ALS)	0.0551999525882228	-2.89679318460846	51	13	0.0113141862489121	1149	7161	847,79139,5530,5879,5534,596,54205,5532,598,10452,4217,1432,57679	CAT,DERL1,PPP3CA,RAC1,PPP3R1,BCL2,CYCS,PPP3CB,BCL2L1,TOMM40,MAP3K5,MAPK14,ALS2
ko05014	Amyotrophic lateral sclerosis (ALS)	0.0551999525882228	-2.89679318460846	51	13	0.0113141862489121	1149	7161	847,79139,5530,5879,5534,596,54205,5532,598,10452,4217,1432,57679	CAT,DERL1,PPP3CA,RAC1,PPP3R1,BCL2,CYCS,PPP3CB,BCL2L1,TOMM40,MAP3K5,MAPK14,ALS2
hsa00511	Other glycan degradation	0.055531643834189	-2.89080226153416	18	6	0.00522193211488251	1149	7161	4125,3073,4126,4758,3074,2629	MAN2B1,HEXA,MANBA,NEU1,HEXB,GBA
ko00511	Other glycan degradation	0.055531643834189	-2.89080226153416	18	6	0.00522193211488251	1149	7161	4125,3073,4126,4758,3074,2629	MAN2B1,HEXA,MANBA,NEU1,HEXB,GBA
M00073	N-glycan precursor trimming	0.0563721650788815	-2.87577976927283	6	3	0.00261096605744125	1149	7161	11253,4121,7841	MAN1B1,MAN1A1,MOGS
hsa_M00090	Phosphatidylcholine (PC) biosynthesis, choline => PC	0.0563721650788815	-2.87577976927283	6	3	0.00261096605744125	1149	7161	1120,56994,1119	CHKB,CHPT1,CHKA
hsa_M00048	Inosine monophosphate biosynthesis, PRPP + glutamine => IMP	0.0563721650788815	-2.87577976927283	6	3	0.00261096605744125	1149	7161	158,2618,471	ADSL,GART,ATIC
M00395	Decapping complex	0.0563721650788815	-2.87577976927283	6	3	0.00261096605744125	1149	7161	55802,219988,80153	DCP1A,PATL1,EDC3
hsa_M00073	N-glycan precursor trimming	0.0563721650788815	-2.87577976927283	6	3	0.00261096605744125	1149	7161	11253,4121,7841	MAN1B1,MAN1A1,MOGS
M00090	Phosphatidylcholine (PC) biosynthesis, choline => PC	0.0563721650788815	-2.87577976927283	6	3	0.00261096605744125	1149	7161	1120,56994,1119	CHKB,CHPT1,CHKA
M00048	Inosine monophosphate biosynthesis, PRPP + glutamine => IMP	0.0563721650788815	-2.87577976927283	6	3	0.00261096605744125	1149	7161	158,2618,471	ADSL,GART,ATIC
hsa_M00395	Decapping complex	0.0563721650788815	-2.87577976927283	6	3	0.00261096605744125	1149	7161	55802,219988,80153	DCP1A,PATL1,EDC3
hsa05215	Prostate cancer	0.0564878577185004	-2.87372957156286	87	20	0.0174064403829417	1149	7161	5170,4893,5894,208,1871,3845,5605,5595,5925,4193,5728,5296,1869,1027,596,1385,5594,1017,1870,3265	PDPK1,NRAS,RAF1,AKT2,E2F3,KRAS,MAP2K2,MAPK3,RB1,MDM2,PTEN,PIK3R2,E2F1,CDKN1B,BCL2,CREB1,MAPK1,CDK2,E2F2,HRAS
ko05215	Prostate cancer	0.0564878577185004	-2.87372957156286	87	20	0.0174064403829417	1149	7161	5170,4893,5894,208,1871,3845,5605,5595,5925,4193,5728,5296,1869,1027,596,1385,5594,1017,1870,3265	PDPK1,NRAS,RAF1,AKT2,E2F3,KRAS,MAP2K2,MAPK3,RB1,MDM2,PTEN,PIK3R2,E2F1,CDKN1B,BCL2,CREB1,MAPK1,CDK2,E2F2,HRAS
ko04921	Oxytocin signaling pathway	0.059723425930819	-2.81803094139896	152	32	0.0278503046127067	1149	7161	5564,4659,5894,5562,5532,5997,5566,140465,29904,805,4775,115,54776,2771,818,113,5530,4893,387,3845,4773,2002,5605,5595,2778,782,2983,5534,60,6093,5594,3265	PRKAB1,PPP1R12A,RAF1,PRKAA1,PPP3CB,RGS2,PRKACA,MYL6B,EEF2K,CALM2,NFATC3,ADCY9,PPP1R12C,GNAI2,CAMK2G,ADCY7,PPP3CA,NRAS,RHOA,KRAS,NFATC2,ELK1,MAP2K2,MAPK3,GNAS,CACNB1,GUCY1B1,PPP3R1,ACTB,ROCK1,MAPK1,HRAS
hsa04921	Oxytocin signaling pathway	0.059723425930819	-2.81803094139896	152	32	0.0278503046127067	1149	7161	5564,4659,5894,5562,5532,5997,5566,140465,29904,805,4775,115,54776,2771,818,113,5530,4893,387,3845,4773,2002,5605,5595,2778,782,2983,5534,60,6093,5594,3265	PRKAB1,PPP1R12A,RAF1,PRKAA1,PPP3CB,RGS2,PRKACA,MYL6B,EEF2K,CALM2,NFATC3,ADCY9,PPP1R12C,GNAI2,CAMK2G,ADCY7,PPP3CA,NRAS,RHOA,KRAS,NFATC2,ELK1,MAP2K2,MAPK3,GNAS,CACNB1,GUCY1B1,PPP3R1,ACTB,ROCK1,MAPK1,HRAS
hsa_M00353	Spliceosome, Prp19/CDC5L complex	0.0598693764906548	-2.81559014848603	14	5	0.00435161009573542	1149	7161	56259,3304,10084,988,27339	CTNNBL1,HSPA1B,PQBP1,CDC5L,PRPF19
M00353	Spliceosome, Prp19/CDC5L complex	0.0598693764906548	-2.81559014848603	14	5	0.00435161009573542	1149	7161	56259,3304,10084,988,27339	CTNNBL1,HSPA1B,PQBP1,CDC5L,PRPF19
hsa_M00391	Exosome, eukaryotes	0.0617739627025824	-2.78427331878899	10	4	0.00348128807658834	1149	7161	5393,118460,23016,51013	EXOSC9,EXOSC6,EXOSC7,EXOSC1
hsa_M00693	Cell cycle - G2/M transition	0.0617739627025824	-2.78427331878899	10	4	0.00348128807658834	1149	7161	890,891,1017,9133	CCNA2,CCNB1,CDK2,CCNB2
M00693	Cell cycle - G2/M transition	0.0617739627025824	-2.78427331878899	10	4	0.00348128807658834	1149	7161	890,891,1017,9133	CCNA2,CCNB1,CDK2,CCNB2
M00391	Exosome, eukaryotes	0.0617739627025824	-2.78427331878899	10	4	0.00348128807658834	1149	7161	5393,118460,23016,51013	EXOSC9,EXOSC6,EXOSC7,EXOSC1
ko04213	Longevity regulating pathway - multiple species	0.0622029414550085	-2.7773529900817	62	15	0.0130548302872063	1149	7161	847,5564,4893,208,5296,115,5562,3845,84335,5566,2309,3265,3066,3304,113	CAT,PRKAB1,NRAS,AKT2,PIK3R2,ADCY9,PRKAA1,KRAS,AKT1S1,PRKACA,FOXO3,HRAS,HDAC2,HSPA1B,ADCY7
hsa04213	Longevity regulating pathway - multiple species	0.0622029414550085	-2.7773529900817	62	15	0.0130548302872063	1149	7161	847,5564,4893,208,5296,115,5562,3845,84335,5566,2309,3265,3066,3304,113	CAT,PRKAB1,NRAS,AKT2,PIK3R2,ADCY9,PRKAA1,KRAS,AKT1S1,PRKACA,FOXO3,HRAS,HDAC2,HSPA1B,ADCY7
hsa05205	Proteoglycans in cancer	0.0650819230815914	-2.73210844756586	203	41	0.0356832027850305	1149	7161	4659,5894,5879,7410,288,6383,1432,5566,3693,8323,7023,4193,998,5296,9138,54776,5781,6774,818,7040,5170,4893,387,208,7430,23365,3845,2002,5605,5595,355,1514,4087,81029,3688,1655,60,6093,5594,3265,27250	PPP1R12A,RAF1,RAC1,VAV2,ANK3,SDC2,MAPK14,PRKACA,ITGB5,FZD6,TFAP4,MDM2,CDC42,PIK3R2,ARHGEF1,PPP1R12C,PTPN11,STAT3,CAMK2G,TGFB1,PDPK1,NRAS,RHOA,AKT2,EZR,ARHGEF12,KRAS,ELK1,MAP2K2,MAPK3,FAS,CTSL,SMAD2,WNT5B,ITGB1,DDX5,ACTB,ROCK1,MAPK1,HRAS,PDCD4
ko05205	Proteoglycans in cancer	0.0650819230815914	-2.73210844756586	203	41	0.0356832027850305	1149	7161	4659,5894,5879,7410,288,6383,1432,5566,3693,8323,7023,4193,998,5296,9138,54776,5781,6774,818,7040,5170,4893,387,208,7430,23365,3845,2002,5605,5595,355,1514,4087,81029,3688,1655,60,6093,5594,3265,27250	PPP1R12A,RAF1,RAC1,VAV2,ANK3,SDC2,MAPK14,PRKACA,ITGB5,FZD6,TFAP4,MDM2,CDC42,PIK3R2,ARHGEF1,PPP1R12C,PTPN11,STAT3,CAMK2G,TGFB1,PDPK1,NRAS,RHOA,AKT2,EZR,ARHGEF12,KRAS,ELK1,MAP2K2,MAPK3,FAS,CTSL,SMAD2,WNT5B,ITGB1,DDX5,ACTB,ROCK1,MAPK1,HRAS,PDCD4
ko04320	Dorso-ventral axis formation	0.0675496962094774	-2.69489171185507	28	8	0.00696257615317668	1149	7161	3845,4853,2114,5594,2113,132864,2120,5595	KRAS,NOTCH2,ETS2,MAPK1,ETS1,CPEB2,ETV6,MAPK3
hsa04320	Dorso-ventral axis formation	0.0675496962094774	-2.69489171185507	28	8	0.00696257615317668	1149	7161	3845,4853,2114,5594,2113,132864,2120,5595	KRAS,NOTCH2,ETS2,MAPK1,ETS1,CPEB2,ETV6,MAPK3
M00297	DNA-PK complex	0.0689349373284432	-2.67459215649883	3	2	0.00174064403829417	1149	7161	5591,7520	PRKDC,XRCC5
hsa_M00408	ESCRT-0 complex	0.0689349373284432	-2.67459215649883	3	2	0.00174064403829417	1149	7161	9146,8027	HGS,STAM
M00408	ESCRT-0 complex	0.0689349373284432	-2.67459215649883	3	2	0.00174064403829417	1149	7161	9146,8027	HGS,STAM
hsa_M00297	DNA-PK complex	0.0689349373284432	-2.67459215649883	3	2	0.00174064403829417	1149	7161	5591,7520	PRKDC,XRCC5
M00341	Proteasome, 19S regulatory particle (PA700)	0.0705495330973346	-2.65144021874441	19	6	0.00522193211488251	1149	7161	5708,5707,5700,5714,5709,5704	PSMD2,PSMD1,PSMC1,PSMD8,PSMD3,PSMC4
hsa_M00341	Proteasome, 19S regulatory particle (PA700)	0.0705495330973346	-2.65144021874441	19	6	0.00522193211488251	1149	7161	5708,5707,5700,5714,5709,5704	PSMD2,PSMD1,PSMC1,PSMD8,PSMD3,PSMC4
hsa04910	Insulin signaling pathway	0.0717667387104177	-2.63433415941953	138	29	0.0252393385552654	1149	7161	5170,5564,4893,7249,9322,5894,208,5562,5575,10211,3845,2002,5140,5566,5605,6009,5595,805,5792,1399,79660,7248,8569,6464,5296,122809,5594,3265,5261	PDPK1,PRKAB1,NRAS,TSC2,TRIP10,RAF1,AKT2,PRKAA1,PRKAR1B,FLOT1,KRAS,ELK1,PDE3B,PRKACA,MAP2K2,RHEB,MAPK3,CALM2,PTPRF,CRKL,PPP1R3B,TSC1,MKNK1,SHC1,PIK3R2,SOCS4,MAPK1,HRAS,PHKG2
ko04910	Insulin signaling pathway	0.0717667387104177	-2.63433415941953	138	29	0.0252393385552654	1149	7161	5170,5564,4893,7249,9322,5894,208,5562,5575,10211,3845,2002,5140,5566,5605,6009,5595,805,5792,1399,79660,7248,8569,6464,5296,122809,5594,3265,5261	PDPK1,PRKAB1,NRAS,TSC2,TRIP10,RAF1,AKT2,PRKAA1,PRKAR1B,FLOT1,KRAS,ELK1,PDE3B,PRKACA,MAP2K2,RHEB,MAPK3,CALM2,PTPRF,CRKL,PPP1R3B,TSC1,MKNK1,SHC1,PIK3R2,SOCS4,MAPK1,HRAS,PHKG2
M00359	Aminoacyl-tRNA biosynthesis, eukaryotes	0.0719193752650529	-2.63220957538246	38	10	0.00870322019147084	1149	7161	2193,2058,51520,3735,3376,3035,5859,55699,6897,79587	FARSA,EPRS,LARS,KARS,IARS,HARS,QARS,IARS2,TARS,CARS2
hsa_M00359	Aminoacyl-tRNA biosynthesis, eukaryotes	0.0719193752650529	-2.63220957538246	38	10	0.00870322019147084	1149	7161	2193,2058,51520,3735,3376,3035,5859,55699,6897,79587	FARSA,EPRS,LARS,KARS,IARS,HARS,QARS,IARS2,TARS,CARS2
hsa03008	Ribosome biogenesis in eukaryotes	0.0729824115226745	-2.61753680490954	79	18	0.0156657963446475	1149	7161	54913,29107,84135,23560,1457,9790,79631,54433,55341,4931,51096,10607,10248,6949,2091,84916,51068,55916	RPP25,NXT1,UTP15,GTPBP4,CSNK2A1,BMS1,EFL1,GAR1,LSG1,NVL,UTP18,TBL3,POP7,TCOF1,FBL,UTP4,NMD3,NXT2
ko03008	Ribosome biogenesis in eukaryotes	0.0729824115226745	-2.61753680490954	79	18	0.0156657963446475	1149	7161	54913,29107,84135,23560,1457,9790,79631,54433,55341,4931,51096,10607,10248,6949,2091,84916,51068,55916	RPP25,NXT1,UTP15,GTPBP4,CSNK2A1,BMS1,EFL1,GAR1,LSG1,NVL,UTP18,TBL3,POP7,TCOF1,FBL,UTP4,NMD3,NXT2
hsa01521	EGFR tyrosine kinase inhibitor resistance	0.0729824115226745	-2.61753680490954	79	18	0.0156657963446475	1149	7161	4893,4763,208,5894,3845,598,2309,5605,5595,2261,6464,3716,5728,5296,596,6774,5594,3265	NRAS,NF1,AKT2,RAF1,KRAS,BCL2L1,FOXO3,MAP2K2,MAPK3,FGFR3,SHC1,JAK1,PTEN,PIK3R2,BCL2,STAT3,MAPK1,HRAS
ko01521	EGFR tyrosine kinase inhibitor resistance	0.0729824115226745	-2.61753680490954	79	18	0.0156657963446475	1149	7161	4893,4763,208,5894,3845,598,2309,5605,5595,2261,6464,3716,5728,5296,596,6774,5594,3265	NRAS,NF1,AKT2,RAF1,KRAS,BCL2L1,FOXO3,MAP2K2,MAPK3,FGFR3,SHC1,JAK1,PTEN,PIK3R2,BCL2,STAT3,MAPK1,HRAS
ko04810	Regulation of actin cytoskeleton	0.075540705657193	-2.58308362023771	211	42	0.0365535248041775	1149	7161	10163,4659,5894,5879,7410,4627,10787,3693,5305,23396,7409,1399,2261,998,3696,10092,5296,9138,54776,200576,2149,1072,23191,387,4893,79837,7430,23365,3845,26999,10552,5605,5595,2768,7454,3984,3688,60,6093,5594,3265,103910	WASF2,PPP1R12A,RAF1,RAC1,VAV2,MYH9,NCKAP1,ITGB5,PIP4K2A,PIP5K1C,VAV1,CRKL,FGFR3,CDC42,ITGB8,ARPC5,PIK3R2,ARHGEF1,PPP1R12C,PIKFYVE,F2R,CFL1,CYFIP1,RHOA,NRAS,PIP4K2C,EZR,ARHGEF12,KRAS,CYFIP2,ARPC1A,MAP2K2,MAPK3,GNA12,WAS,LIMK1,ITGB1,ACTB,ROCK1,MAPK1,HRAS,MYL12B
hsa04810	Regulation of actin cytoskeleton	0.075540705657193	-2.58308362023771	211	42	0.0365535248041775	1149	7161	10163,4659,5894,5879,7410,4627,10787,3693,5305,23396,7409,1399,2261,998,3696,10092,5296,9138,54776,200576,2149,1072,23191,387,4893,79837,7430,23365,3845,26999,10552,5605,5595,2768,7454,3984,3688,60,6093,5594,3265,103910	WASF2,PPP1R12A,RAF1,RAC1,VAV2,MYH9,NCKAP1,ITGB5,PIP4K2A,PIP5K1C,VAV1,CRKL,FGFR3,CDC42,ITGB8,ARPC5,PIK3R2,ARHGEF1,PPP1R12C,PIKFYVE,F2R,CFL1,CYFIP1,RHOA,NRAS,PIP4K2C,EZR,ARHGEF12,KRAS,CYFIP2,ARPC1A,MAP2K2,MAPK3,GNA12,WAS,LIMK1,ITGB1,ACTB,ROCK1,MAPK1,HRAS,MYL12B
hsa05218	Melanoma	0.0767796019062605	-2.56681627428538	69	16	0.0139251523063534	1149	7161	4893,5894,208,1871,3845,5605,5595,5925,4193,5728,5296,1869,1870,5594,3265,1029	NRAS,RAF1,AKT2,E2F3,KRAS,MAP2K2,MAPK3,RB1,MDM2,PTEN,PIK3R2,E2F1,E2F2,MAPK1,HRAS,CDKN2A
ko05218	Melanoma	0.0767796019062605	-2.56681627428538	69	16	0.0139251523063534	1149	7161	4893,5894,208,1871,3845,5605,5595,5925,4193,5728,5296,1869,1870,5594,3265,1029	NRAS,RAF1,AKT2,E2F3,KRAS,MAP2K2,MAPK3,RB1,MDM2,PTEN,PIK3R2,E2F1,E2F2,MAPK1,HRAS,CDKN2A
M00158	F-type ATPase, eukaryotes	0.0783601025956015	-2.54644037662128	15	5	0.00435161009573542	1149	7161	498,506,9551,518,522	ATP5F1A,ATP5F1B,ATP5MF,ATP5MC3,ATP5PF
M00340	Proteasome, 20S core particle	0.0783601025956015	-2.54644037662128	15	5	0.00435161009573542	1149	7161	5682,5687,143471,5691,5695	PSMA1,PSMA6,PSMA8,PSMB3,PSMB7
hsa_M00158	F-type ATPase, eukaryotes	0.0783601025956015	-2.54644037662128	15	5	0.00435161009573542	1149	7161	498,506,9551,518,522	ATP5F1A,ATP5F1B,ATP5MF,ATP5MC3,ATP5PF
hsa_M00340	Proteasome, 20S core particle	0.0783601025956015	-2.54644037662128	15	5	0.00435161009573542	1149	7161	5682,5687,143471,5691,5695	PSMA1,PSMA6,PSMA8,PSMB3,PSMB7
hsa04611	Platelet activation	0.0800212187126615	-2.52546344556828	123	26	0.0226283724978242	1149	7161	387,4659,208,23365,1432,5566,4067,5595,83706,2778,5906,7408,2983,8773,9138,115,5296,3688,84876,60,6093,2149,2771,5594,103910,113	RHOA,PPP1R12A,AKT2,ARHGEF12,MAPK14,PRKACA,LYN,MAPK3,FERMT3,GNAS,RAP1A,VASP,GUCY1B1,SNAP23,ARHGEF1,ADCY9,PIK3R2,ITGB1,ORAI1,ACTB,ROCK1,F2R,GNAI2,MAPK1,MYL12B,ADCY7
ko00620	Pyruvate metabolism	0.0834428931550402	-2.4835927954123	39	10	0.00870322019147084	1149	7161	97,4191,3939,38,4190,2739,5315,3029,223,3945	ACYP1,MDH2,LDHA,ACAT1,MDH1,GLO1,PKM,HAGH,ALDH9A1,LDHB
hsa00620	Pyruvate metabolism	0.0834428931550402	-2.4835927954123	39	10	0.00870322019147084	1149	7161	97,4191,3939,38,4190,2739,5315,3029,3945,223	ACYP1,MDH2,LDHA,ACAT1,MDH1,GLO1,PKM,HAGH,LDHB,ALDH9A1
ko04660	T cell receptor signaling pathway	0.0850572058683063	-2.46443123864627	102	22	0.0191470844212359	1149	7161	5170,5530,387,4893,4690,5894,208,7410,4773,3845,5532,1432,5605,5595,7409,4775,998,5296,5534,9020,5594,3265	PDPK1,PPP3CA,RHOA,NRAS,NCK1,RAF1,AKT2,VAV2,NFATC2,KRAS,PPP3CB,MAPK14,MAP2K2,MAPK3,VAV1,NFATC3,CDC42,PIK3R2,PPP3R1,MAP3K14,MAPK1,HRAS
hsa04660	T cell receptor signaling pathway	0.0850572058683063	-2.46443123864627	102	22	0.0191470844212359	1149	7161	5170,5530,387,4893,4690,5894,208,7410,4773,3845,5532,1432,5605,5595,7409,4775,998,5296,5534,9020,5594,3265	PDPK1,PPP3CA,RHOA,NRAS,NCK1,RAF1,AKT2,VAV2,NFATC2,KRAS,PPP3CB,MAPK14,MAP2K2,MAPK3,VAV1,NFATC3,CDC42,PIK3R2,PPP3R1,MAP3K14,MAPK1,HRAS
M00092	Phosphatidylethanolamine (PE) biosynthesis, ethanolamine => PE	0.0871343536396182	-2.44030405681616	7	3	0.00261096605744125	1149	7161	1120,5833,1119	CHKB,PCYT2,CHKA
M00398	Sm core complex	0.0871343536396182	-2.44030405681616	7	3	0.00261096605744125	1149	7161	6637,6634,6628	SNRPG,SNRPD3,SNRPB
hsa_M00398	Sm core complex	0.0871343536396182	-2.44030405681616	7	3	0.00261096605744125	1149	7161	6637,6634,6628	SNRPG,SNRPD3,SNRPB
hsa_M00092	Phosphatidylethanolamine (PE) biosynthesis, ethanolamine => PE	0.0871343536396182	-2.44030405681616	7	3	0.00261096605744125	1149	7161	1120,5833,1119	CHKB,PCYT2,CHKA
hsa04022	cGMP-PKG signaling pathway	0.0880904655153111	-2.42939097533232	163	33	0.0287206266318538	1149	7161	4659,5894,4205,5532,5997,805,4775,7408,488,115,1385,2771,1386,113,10105,5530,387,208,7417,4773,154,4209,7416,5140,292,5605,5595,2768,476,2983,5534,6093,5594	PPP1R12A,RAF1,MEF2A,PPP3CB,RGS2,CALM2,NFATC3,VASP,ATP2A2,ADCY9,CREB1,GNAI2,ATF2,ADCY7,PPIF,PPP3CA,RHOA,AKT2,VDAC2,NFATC2,ADRB2,MEF2D,VDAC1,PDE3B,SLC25A5,MAP2K2,MAPK3,GNA12,ATP1A1,GUCY1B1,PPP3R1,ROCK1,MAPK1
ko04022	cGMP-PKG signaling pathway	0.0880904655153111	-2.42939097533232	163	33	0.0287206266318538	1149	7161	4659,5894,4205,5532,5997,805,4775,7408,488,115,1385,2771,1386,113,10105,5530,387,208,7417,4773,154,4209,7416,5140,292,5605,5595,2768,476,2983,5534,6093,5594	PPP1R12A,RAF1,MEF2A,PPP3CB,RGS2,CALM2,NFATC3,VASP,ATP2A2,ADCY9,CREB1,GNAI2,ATF2,ADCY7,PPIF,PPP3CA,RHOA,AKT2,VDAC2,NFATC2,ADRB2,MEF2D,VDAC1,PDE3B,SLC25A5,MAP2K2,MAPK3,GNA12,ATP1A1,GUCY1B1,PPP3R1,ROCK1,MAPK1
ko05130	Pathogenic Escherichia coli infection	0.0918720199009265	-2.38735875842771	55	13	0.0113141862489121	1149	7161	387,7454,998,4690,10092,3688,9181,7430,7534,60,6093,10552,203068	RHOA,WAS,CDC42,NCK1,ARPC5,ITGB1,ARHGEF2,EZR,YWHAZ,ACTB,ROCK1,ARPC1A,TUBB
hsa05130	Pathogenic Escherichia coli infection	0.0918720199009265	-2.38735875842771	55	13	0.0113141862489121	1149	7161	387,7454,998,4690,10092,3688,9181,7430,7534,60,6093,10552,203068	RHOA,WAS,CDC42,NCK1,ARPC5,ITGB1,ARHGEF2,EZR,YWHAZ,ACTB,ROCK1,ARPC1A,TUBB
ko01200	Carbon metabolism	0.0931874204434667	-2.37314254018292	114	24	0.02088772845953	1149	7161	4594,8802,4191,3419,7086,2746,83440,4967,5315,6389,6390,847,2806,5634,1431,8801,38,4190,34,2821,3420,6888,5223,5214	MUT,SUCLG1,MDH2,IDH3A,TKT,GLUD1,ADPGK,OGDH,PKM,SDHA,SDHB,CAT,GOT2,PRPS2,CS,SUCLG2,ACAT1,MDH1,ACADM,GPI,IDH3B,TALDO1,PGAM1,PFKP
hsa01200	Carbon metabolism	0.0931874204434667	-2.37314254018292	114	24	0.02088772845953	1149	7161	4594,8802,4191,3419,7086,2746,83440,4967,5315,6389,6390,847,2806,5634,1431,8801,38,4190,34,2821,3420,6888,5223,5214	MUT,SUCLG1,MDH2,IDH3A,TKT,GLUD1,ADPGK,OGDH,PKM,SDHA,SDHB,CAT,GOT2,PRPS2,CS,SUCLG2,ACAT1,MDH1,ACADM,GPI,IDH3B,TALDO1,PGAM1,PFKP
M00695	cAMP signaling	0.0995381306229668	-2.30721448588714	16	5	0.00435161009573542	1149	7161	2778,2771,5566,115,113	GNAS,GNAI2,PRKACA,ADCY9,ADCY7
hsa_M00695	cAMP signaling	0.0995381306229668	-2.30721448588714	16	5	0.00435161009573542	1149	7161	2778,2771,5566,115,113	GNAS,GNAI2,PRKACA,ADCY9,ADCY7
ko05231	Choline metabolism in cancer	0.104268668086383	-2.26078436396143	99	21	0.0182767624020888	1149	7161	10163,5170,4893,7249,208,5894,5879,3845,1120,5605,6009,5595,23396,1119,7248,7454,23446,5296,5594,56994,3265	WASF2,PDPK1,NRAS,TSC2,AKT2,RAF1,RAC1,KRAS,CHKB,MAP2K2,RHEB,MAPK3,PIP5K1C,CHKA,TSC1,WAS,SLC44A1,PIK3R2,MAPK1,CHPT1,HRAS
hsa05231	Choline metabolism in cancer	0.104268668086383	-2.26078436396143	99	21	0.0182767624020888	1149	7161	10163,5170,4893,7249,208,5894,5879,3845,1120,5605,6009,5595,23396,1119,7248,7454,23446,5296,5594,56994,3265	WASF2,PDPK1,NRAS,TSC2,AKT2,RAF1,RAC1,KRAS,CHKB,MAP2K2,RHEB,MAPK3,PIP5K1C,CHKA,TSC1,WAS,SLC44A1,PIK3R2,MAPK1,CHPT1,HRAS
M00154	Cytochrome c oxidase	0.106841667433543	-2.23640728403379	21	6	0.00522193211488251	1149	7161	9377,1355,1329,1327,9167,1351	COX5A,COX15,COX5B,COX4I1,COX7A2L,COX8A
hsa_M00154	Cytochrome c oxidase	0.106841667433543	-2.23640728403379	21	6	0.00522193211488251	1149	7161	9377,1355,1329,1327,9167,1351	COX5A,COX15,COX5B,COX4I1,COX7A2L,COX8A
hsa04664	Fc epsilon RI signaling pathway	0.107867876149453	-2.22684816977118	67	15	0.0130548302872063	1149	7161	7409,5170,4893,5894,208,5296,5879,7410,3845,5594,4067,1432,3265,5605,5595	VAV1,PDPK1,NRAS,RAF1,AKT2,PIK3R2,RAC1,VAV2,KRAS,MAPK1,LYN,MAPK14,HRAS,MAP2K2,MAPK3
hsa04720	Long-term potentiation	0.107867876149453	-2.22684816977118	67	15	0.0130548302872063	1149	7161	805,5530,5906,4893,5894,6195,5534,3845,5532,5594,5566,3265,5605,818,5595	CALM2,PPP3CA,RAP1A,NRAS,RAF1,RPS6KA1,PPP3R1,KRAS,PPP3CB,MAPK1,PRKACA,HRAS,MAP2K2,CAMK2G,MAPK3
ko04664	Fc epsilon RI signaling pathway	0.107867876149453	-2.22684816977118	67	15	0.0130548302872063	1149	7161	7409,5170,4893,5894,208,5296,5879,7410,3845,5594,4067,1432,3265,5605,5595	VAV1,PDPK1,NRAS,RAF1,AKT2,PIK3R2,RAC1,VAV2,KRAS,MAPK1,LYN,MAPK14,HRAS,MAP2K2,MAPK3
ko04720	Long-term potentiation	0.107867876149453	-2.22684816977118	67	15	0.0130548302872063	1149	7161	805,5530,5906,4893,5894,6195,5534,3845,5532,5594,5566,3265,5605,818,5595	CALM2,PPP3CA,RAP1A,NRAS,RAF1,RPS6KA1,PPP3R1,KRAS,PPP3CB,MAPK1,PRKACA,HRAS,MAP2K2,CAMK2G,MAPK3
M00388	ECS complex	0.112105684902049	-2.18831323741513	12	4	0.00348128807658834	1149	7161	30837,122809,9306,9655	SOCS7,SOCS4,SOCS6,SOCS5
hsa_M00388	ECS complex	0.112105684902049	-2.18831323741513	12	4	0.00348128807658834	1149	7161	30837,122809,9306,9655	SOCS7,SOCS4,SOCS6,SOCS5
hsa00564	Glycerophospholipid metabolism	0.117496546319642	-2.14134633885423	95	20	0.0174064403829417	1149	7161	8760,9489,10554,56894,1120,10423,6901,253558,1119,23646,10555,9663,254531,154141,5833,23171,79888,56994,9791,11313	CDS2,PGS1,AGPAT1,AGPAT3,CHKB,CDIPT,TAZ,LCLAT1,CHKA,PLD3,AGPAT2,LPIN2,LPCAT4,MBOAT1,PCYT2,GPD1L,LPCAT1,CHPT1,PTDSS1,LYPLA2
ko00564	Glycerophospholipid metabolism	0.117496546319642	-2.14134633885423	95	20	0.0174064403829417	1149	7161	8760,9489,10554,56894,1120,10423,6901,253558,1119,23646,10555,9663,254531,154141,5833,79888,56994,23171,9791,11313	CDS2,PGS1,AGPAT1,AGPAT3,CHKB,CDIPT,TAZ,LCLAT1,CHKA,PLD3,AGPAT2,LPIN2,LPCAT4,MBOAT1,PCYT2,LPCAT1,CHPT1,GPD1L,PTDSS1,LYPLA2
M00089	Triacylglycerol biosynthesis	0.123254360378847	-2.09350508835778	17	5	0.00435161009573542	1149	7161	56894,154141,10555,253558,10554	AGPAT3,MBOAT1,AGPAT2,LCLAT1,AGPAT1
M00337	Immunoproteasome	0.123254360378847	-2.09350508835778	17	5	0.00435161009573542	1149	7161	5682,5687,5698,143471,5691	PSMA1,PSMA6,PSMB9,PSMA8,PSMB3
hsa_M00337	Immunoproteasome	0.123254360378847	-2.09350508835778	17	5	0.00435161009573542	1149	7161	5682,5687,5698,143471,5691	PSMA1,PSMA6,PSMB9,PSMA8,PSMB3
hsa_M00089	Triacylglycerol biosynthesis	0.123254360378847	-2.09350508835778	17	5	0.00435161009573542	1149	7161	56894,154141,10555,253558,10554	AGPAT3,MBOAT1,AGPAT2,LCLAT1,AGPAT1
hsa_M00680	TGF-beta signaling	0.12330250019068	-2.09311459172074	8	3	0.00261096605744125	1149	7161	7040,4087,4089	TGFB1,SMAD2,SMAD4
hsa_M00010	Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate	0.12330250019068	-2.09311459172074	8	3	0.00261096605744125	1149	7161	3420,3419,1431	IDH3B,IDH3A,CS
M00680	TGF-beta signaling	0.12330250019068	-2.09311459172074	8	3	0.00261096605744125	1149	7161	7040,4087,4089	TGFB1,SMAD2,SMAD4
M00010	Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate	0.12330250019068	-2.09311459172074	8	3	0.00261096605744125	1149	7161	3420,3419,1431	IDH3B,IDH3A,CS
hsa_M00288	RPA complex	0.123362403789649	-2.09262888338381	4	2	0.00174064403829417	1149	7161	6118,6117	RPA2,RPA1
M00288	RPA complex	0.123362403789649	-2.09262888338381	4	2	0.00174064403829417	1149	7161	6118,6117	RPA2,RPA1
M00402	Translocon-associated protein (TRAP) complex	0.123362403789649	-2.09262888338381	4	2	0.00174064403829417	1149	7161	6746,6745	SSR2,SSR1
hsa_M00387	SCF-FBW7 complex	0.123362403789649	-2.09262888338381	4	2	0.00174064403829417	1149	7161	8454,9978	CUL1,RBX1
hsa_M00286	GINS complex	0.123362403789649	-2.09262888338381	4	2	0.00174064403829417	1149	7161	9837,84296	GINS1,GINS4
M00381	SCF-SKP2 complex	0.123362403789649	-2.09262888338381	4	2	0.00174064403829417	1149	7161	8454,9978	CUL1,RBX1
hsa_M00381	SCF-SKP2 complex	0.123362403789649	-2.09262888338381	4	2	0.00174064403829417	1149	7161	8454,9978	CUL1,RBX1
hsa_M00133	Polyamine biosynthesis, arginine => agmatine => putrescine => spermidine	0.123362403789649	-2.09262888338381	4	2	0.00174064403829417	1149	7161	6723,262	SRM,AMD1
M00384	Cul3-SPOP complex	0.123362403789649	-2.09262888338381	4	2	0.00174064403829417	1149	7161	9978,8452	RBX1,CUL3
M00387	SCF-FBW7 complex	0.123362403789649	-2.09262888338381	4	2	0.00174064403829417	1149	7161	8454,9978	CUL1,RBX1
hsa_M00148	Succinate dehydrogenase (ubiquinone)	0.123362403789649	-2.09262888338381	4	2	0.00174064403829417	1149	7161	6390,6389	SDHB,SDHA
M00133	Polyamine biosynthesis, arginine => agmatine => putrescine => spermidine	0.123362403789649	-2.09262888338381	4	2	0.00174064403829417	1149	7161	6723,262	SRM,AMD1
hsa_M00402	Translocon-associated protein (TRAP) complex	0.123362403789649	-2.09262888338381	4	2	0.00174064403829417	1149	7161	6746,6745	SSR2,SSR1
M00148	Succinate dehydrogenase (ubiquinone)	0.123362403789649	-2.09262888338381	4	2	0.00174064403829417	1149	7161	6390,6389	SDHB,SDHA
hsa_M00390	Exosome, archaea	0.123362403789649	-2.09262888338381	4	2	0.00174064403829417	1149	7161	23016,51013	EXOSC7,EXOSC1
M00286	GINS complex	0.123362403789649	-2.09262888338381	4	2	0.00174064403829417	1149	7161	9837,84296	GINS1,GINS4
hsa_M00384	Cul3-SPOP complex	0.123362403789649	-2.09262888338381	4	2	0.00174064403829417	1149	7161	9978,8452	RBX1,CUL3
M00390	Exosome, archaea	0.123362403789649	-2.09262888338381	4	2	0.00174064403829417	1149	7161	23016,51013	EXOSC7,EXOSC1
ko00640	Propanoate metabolism	0.128667326526641	-2.05052506975317	32	8	0.00696257615317668	1149	7161	38,23417,8801,34,8802,4594,3939,3945	ACAT1,MLYCD,SUCLG2,ACADM,SUCLG1,MUT,LDHA,LDHB
hsa00640	Propanoate metabolism	0.128667326526641	-2.05052506975317	32	8	0.00696257615317668	1149	7161	38,23417,8801,34,8802,4594,3939,3945	ACAT1,MLYCD,SUCLG2,ACADM,SUCLG1,MUT,LDHA,LDHB
ko03015	mRNA surveillance pathway	0.132409341848437	-2.02185708020066	91	19	0.0165361183637946	1149	7161	29107,23708,9939,10921,80335,8189,8761,10914,5515,5976,5525,9775,53918,26019,10898,55844,26986,1477,55916	NXT1,GSPT2,RBM8A,RNPS1,WDR82,SYMPK,PABPC4,PAPOLA,PPP2CA,UPF1,PPP2R5A,EIF4A3,PELO,UPF2,CPSF4,PPP2R2D,PABPC1,CSTF1,NXT2
hsa03015	mRNA surveillance pathway	0.132409341848437	-2.02185708020066	91	19	0.0165361183637946	1149	7161	29107,23708,9939,10921,80335,8189,8761,10914,5515,5976,5525,9775,53918,26019,10898,55844,26986,1477,55916	NXT1,GSPT2,RBM8A,RNPS1,WDR82,SYMPK,PABPC4,PAPOLA,PPP2CA,UPF1,PPP2R5A,EIF4A3,PELO,UPF2,CPSF4,PPP2R2D,PABPC1,CSTF1,NXT2
M00403	HRD1/SEL1 ERAD complex	0.142310561436852	-1.9497435571264	13	4	0.00348128807658834	1149	7161	79139,84447,55666,6400	DERL1,SYVN1,NPLOC4,SEL1L
hsa03450	Non-homologous end-joining	0.142310561436852	-1.9497435571264	13	4	0.00348128807658834	1149	7161	64421,7518,5591,7520	DCLRE1C,XRCC4,PRKDC,XRCC5
hsa_M00403	HRD1/SEL1 ERAD complex	0.142310561436852	-1.9497435571264	13	4	0.00348128807658834	1149	7161	79139,84447,55666,6400	DERL1,SYVN1,NPLOC4,SEL1L
ko03450	Non-homologous end-joining	0.142310561436852	-1.9497435571264	13	4	0.00348128807658834	1149	7161	64421,7518,5591,7520	DCLRE1C,XRCC4,PRKDC,XRCC5
hsa04152	AMPK signaling pathway	0.143939536654891	-1.93836195192328	120	24	0.02088772845953	1149	7161	5170,51552,5564,7249,9230,208,5562,5209,84335,2309,6009,29904,5515,7248,4218,890,5525,5296,51719,23417,6794,1385,55844,5214	PDPK1,RAB14,PRKAB1,TSC2,RAB11B,AKT2,PRKAA1,PFKFB3,AKT1S1,FOXO3,RHEB,EEF2K,PPP2CA,TSC1,RAB8A,CCNA2,PPP2R5A,PIK3R2,CAB39,MLYCD,STK11,CREB1,PPP2R2D,PFKP
ko04152	AMPK signaling pathway	0.143939536654891	-1.93836195192328	120	24	0.02088772845953	1149	7161	5170,51552,5564,7249,9230,208,5562,5209,84335,2309,6009,29904,5515,7248,4218,890,5525,5296,51719,23417,6794,1385,55844,5214	PDPK1,RAB14,PRKAB1,TSC2,RAB11B,AKT2,PRKAA1,PFKFB3,AKT1S1,FOXO3,RHEB,EEF2K,PPP2CA,TSC1,RAB8A,CCNA2,PPP2R5A,PIK3R2,CAB39,MLYCD,STK11,CREB1,PPP2R2D,PFKP
ko03410	Base excision repair	0.147320888789777	-1.9151421543677	33	8	0.00696257615317668	1149	7161	5111,5426,55247,143,4350,4968,252969,8930	PCNA,POLE,NEIL3,PARP4,MPG,OGG1,NEIL2,MBD4
hsa03410	Base excision repair	0.147320888789777	-1.9151421543677	33	8	0.00696257615317668	1149	7161	5111,5426,55247,143,4350,4968,252969,8930	PCNA,POLE,NEIL3,PARP4,MPG,OGG1,NEIL2,MBD4
ko04915	Estrogen signaling pathway	0.147973681420207	-1.91072084927318	98	20	0.0174064403829417	1149	7161	4893,208,5894,3845,5566,5605,3304,5595,805,2778,6464,115,5296,2289,1385,5594,1386,2771,3265,113	NRAS,AKT2,RAF1,KRAS,PRKACA,MAP2K2,HSPA1B,MAPK3,CALM2,GNAS,SHC1,ADCY9,PIK3R2,FKBP5,CREB1,MAPK1,ATF2,GNAI2,HRAS,ADCY7
hsa04915	Estrogen signaling pathway	0.147973681420207	-1.91072084927318	98	20	0.0174064403829417	1149	7161	4893,208,5894,3845,5566,5605,3304,5595,805,2778,6464,115,5296,2289,1385,5594,1386,2771,3265,113	NRAS,AKT2,RAF1,KRAS,PRKACA,MAP2K2,HSPA1B,MAPK3,CALM2,GNAS,SHC1,ADCY9,PIK3R2,FKBP5,CREB1,MAPK1,ATF2,GNAI2,HRAS,ADCY7
ko01210	2-Oxocarboxylic acid metabolism	0.149301559051156	-1.90178713208591	18	5	0.00435161009573542	1149	7161	3420,2806,3419,587,1431	IDH3B,GOT2,IDH3A,BCAT2,CS
hsa01210	2-Oxocarboxylic acid metabolism	0.149301559051156	-1.90178713208591	18	5	0.00435161009573542	1149	7161	3420,2806,3419,587,1431	IDH3B,GOT2,IDH3A,BCAT2,CS
hsa00630	Glyoxylate and dicarboxylate metabolism	0.149879373374127	-1.89792448591589	28	7	0.00609225413402959	1149	7161	38,847,4190,4594,4191,2653,1431	ACAT1,CAT,MDH1,MUT,MDH2,GCSH,CS
ko00630	Glyoxylate and dicarboxylate metabolism	0.149879373374127	-1.89792448591589	28	7	0.00609225413402959	1149	7161	38,847,4190,4594,4191,2653,1431	ACAT1,CAT,MDH1,MUT,MDH2,GCSH,CS
hsa03060	Protein export	0.150950017611765	-1.89080650615646	23	6	0.00522193211488251	1149	7161	23478,6731,60559,10952,29927,23480	SEC11A,SRP72,SPCS3,SEC61B,SEC61A1,SEC61G
ko03060	Protein export	0.150950017611765	-1.89080650615646	23	6	0.00522193211488251	1149	7161	23478,6731,60559,10952,29927,23480	SEC11A,SRP72,SPCS3,SEC61B,SEC61A1,SEC61G
hsa04730	Long-term depression	0.15480722202939	-1.86557466497814	60	13	0.0113141862489121	1149	7161	2778,5515,2768,4893,2983,5894,3845,5594,4067,2771,3265,5605,5595	GNAS,PPP2CA,GNA12,NRAS,GUCY1B1,RAF1,KRAS,MAPK1,LYN,GNAI2,HRAS,MAP2K2,MAPK3
ko04730	Long-term depression	0.15480722202939	-1.86557466497814	60	13	0.0113141862489121	1149	7161	2778,5515,2768,4893,2983,5894,3845,5594,4067,2771,3265,5605,5595	GNAS,PPP2CA,GNA12,NRAS,GUCY1B1,RAF1,KRAS,MAPK1,LYN,GNAI2,HRAS,MAP2K2,MAPK3
hsa04550	Signaling pathways regulating pluripotency of stem cells	0.16319823046557	-1.81278967924639	139	27	0.0234986945169713	1149	7161	4893,208,5894,6929,84108,3845,84759,1432,5605,8323,5595,2261,4087,100532731,3716,81029,8312,3572,5296,8313,1855,4086,5594,6774,3265,4089,1856	NRAS,AKT2,RAF1,TCF3,PCGF6,KRAS,PCGF1,MAPK14,MAP2K2,FZD6,MAPK3,FGFR3,SMAD2,COMMD3-BMI1,JAK1,WNT5B,AXIN1,IL6ST,PIK3R2,AXIN2,DVL1,SMAD1,MAPK1,STAT3,HRAS,SMAD4,DVL2
ko04550	Signaling pathways regulating pluripotency of stem cells	0.16319823046557	-1.81278967924639	139	27	0.0234986945169713	1149	7161	4893,208,5894,6929,84108,3845,84759,1432,5605,8323,5595,2261,4087,100532731,3716,81029,8312,3572,5296,8313,1855,4086,5594,6774,3265,4089,1856	NRAS,AKT2,RAF1,TCF3,PCGF6,KRAS,PCGF1,MAPK14,MAP2K2,FZD6,MAPK3,FGFR3,SMAD2,COMMD3-BMI1,JAK1,WNT5B,AXIN1,IL6ST,PIK3R2,AXIN2,DVL1,SMAD1,MAPK1,STAT3,HRAS,SMAD4,DVL2
M00131	Inositol phosphate metabolism, Ins(1,3,4,5)P4 => Ins(1,3,4)P3 => myo-inositol	0.163800576771387	-1.80910558637653	9	3	0.00261096605744125	1149	7161	3632,54928,3613	INPP5A,IMPAD1,IMPA2
M00078	Heparan sulfate degradation	0.163800576771387	-1.80910558637653	9	3	0.00261096605744125	1149	7161	2799,6448,4669	GNS,SGSH,NAGLU
hsa_M00078	Heparan sulfate degradation	0.163800576771387	-1.80910558637653	9	3	0.00261096605744125	1149	7161	2799,6448,4669	GNS,SGSH,NAGLU
hsa_M00131	Inositol phosphate metabolism, Ins(1,3,4,5)P4 => Ins(1,3,4)P3 => myo-inositol	0.163800576771387	-1.80910558637653	9	3	0.00261096605744125	1149	7161	3632,54928,3613	INPP5A,IMPAD1,IMPA2
hsa04010	MAPK signaling pathway	0.165577884803229	-1.79831359182324	255	47	0.040905134899913	1149	7161	4149,4763,5894,6195,5879,10912,8649,5532,1432,3925,5566,1399,2261,4775,5906,998,994,9020,1386,7040,5530,4893,7867,208,57551,9448,3845,8491,2002,5605,3304,5595,355,4216,782,8569,2768,23118,1845,4616,5534,5778,4217,5536,5594,409,3265	MAX,NF1,RAF1,RPS6KA1,RAC1,GADD45G,LAMTOR3,PPP3CB,MAPK14,STMN1,PRKACA,CRKL,FGFR3,NFATC3,RAP1A,CDC42,CDC25B,MAP3K14,ATF2,TGFB1,PPP3CA,NRAS,MAPKAPK3,AKT2,TAOK1,MAP4K4,KRAS,MAP4K3,ELK1,MAP2K2,HSPA1B,MAPK3,FAS,MAP3K4,CACNB1,MKNK1,GNA12,TAB2,DUSP3,GADD45B,PPP3R1,PTPN7,MAP3K5,PPP5C,MAPK1,ARRB2,HRAS
ko04010	MAPK signaling pathway	0.165577884803229	-1.79831359182324	255	47	0.040905134899913	1149	7161	4149,4763,5894,6195,5879,10912,8649,5532,3925,5566,1432,1399,2261,5906,4775,998,994,9020,1386,7040,5530,4893,7867,208,9448,57551,8491,3845,2002,5605,3304,5595,355,4216,782,2768,8569,23118,1845,4616,5778,5534,5536,4217,5594,409,3265	MAX,NF1,RAF1,RPS6KA1,RAC1,GADD45G,LAMTOR3,PPP3CB,STMN1,PRKACA,MAPK14,CRKL,FGFR3,RAP1A,NFATC3,CDC42,CDC25B,MAP3K14,ATF2,TGFB1,PPP3CA,NRAS,MAPKAPK3,AKT2,MAP4K4,TAOK1,MAP4K3,KRAS,ELK1,MAP2K2,HSPA1B,MAPK3,FAS,MAP3K4,CACNB1,GNA12,MKNK1,TAB2,DUSP3,GADD45B,PTPN7,PPP3R1,PPP5C,MAP3K5,MAPK1,ARRB2,HRAS
ko04072	Phospholipase D signaling pathway	0.165948542386181	-1.79607752430649	145	28	0.0243690165361184	1149	7161	9267,387,4893,7249,208,5894,10554,56894,3845,375,5605,6009,5595,23396,2778,7248,2768,6464,10555,5899,115,5296,1785,5781,2149,5594,3265,113	CYTH1,RHOA,NRAS,TSC2,AKT2,RAF1,AGPAT1,AGPAT3,KRAS,ARF1,MAP2K2,RHEB,MAPK3,PIP5K1C,GNAS,TSC1,GNA12,SHC1,AGPAT2,RALB,ADCY9,PIK3R2,DNM2,PTPN11,F2R,MAPK1,HRAS,ADCY7
hsa04072	Phospholipase D signaling pathway	0.165948542386181	-1.79607752430649	145	28	0.0243690165361184	1149	7161	9267,387,4893,7249,208,5894,10554,56894,3845,375,5605,6009,5595,23396,2778,7248,2768,6464,10555,5899,115,5296,1785,5781,2149,5594,3265,113	CYTH1,RHOA,NRAS,TSC2,AKT2,RAF1,AGPAT1,AGPAT3,KRAS,ARF1,MAP2K2,RHEB,MAPK3,PIP5K1C,GNAS,TSC1,GNA12,SHC1,AGPAT2,RALB,ADCY9,PIK3R2,DNM2,PTPN11,F2R,MAPK1,HRAS,ADCY7
hsa04146	Peroxisome	0.168169581229869	-1.78278239661013	83	17	0.0147954743255004	1149	7161	51703,2181,5827,2053,10654,1891,5052,847,390916,373156,5830,1384,51,25824,4358,23417,215	ACSL5,ACSL3,PXMP2,EPHX2,PMVK,ECH1,PRDX1,CAT,NUDT19,GSTK1,PEX5,CRAT,ACOX1,PRDX5,MPV17,MLYCD,ABCD1
ko04146	Peroxisome	0.168169581229869	-1.78278239661013	83	17	0.0147954743255004	1149	7161	51703,2181,5827,2053,10654,1891,5052,847,390916,373156,5830,1384,51,25824,4358,23417,215	ACSL5,ACSL3,PXMP2,EPHX2,PMVK,ECH1,PRDX1,CAT,NUDT19,GSTK1,PEX5,CRAT,ACOX1,PRDX5,MPV17,MLYCD,ABCD1
hsa_M00147	NADH dehydrogenase (ubiquinone) 1 beta subcomplex	0.17528703541606	-1.741330446344	14	4	0.00348128807658834	1149	7161	4715,4707,4712,4710	NDUFB9,NDUFB1,NDUFB6,NDUFB4
M00147	NADH dehydrogenase (ubiquinone) 1 beta subcomplex	0.17528703541606	-1.741330446344	14	4	0.00348128807658834	1149	7161	4715,4707,4712,4710	NDUFB9,NDUFB1,NDUFB6,NDUFB4
hsa00531	Glycosaminoglycan degradation	0.177427282605425	-1.72919442946898	19	5	0.00435161009573542	1149	7161	2799,6448,3073,4669,3074	GNS,SGSH,HEXA,NAGLU,HEXB
ko00531	Glycosaminoglycan degradation	0.177427282605425	-1.72919442946898	19	5	0.00435161009573542	1149	7161	2799,6448,3073,4669,3074	GNS,SGSH,HEXA,NAGLU,HEXB
hsa_M00385	Cul4-DDB1-DDB2 complex	0.18430210355817	-1.69117900059955	5	2	0.00174064403829417	1149	7161	9978,1642	RBX1,DDB1
M00383	ECV complex	0.18430210355817	-1.69117900059955	5	2	0.00174064403829417	1149	7161	9978,7428	RBX1,VHL
M00380	SCF-BTRC complex	0.18430210355817	-1.69117900059955	5	2	0.00174064403829417	1149	7161	8454,9978	CUL1,RBX1
M00289	RF-C complex	0.18430210355817	-1.69117900059955	5	2	0.00174064403829417	1149	7161	5983,5982	RFC3,RFC2
hsa_M00380	SCF-BTRC complex	0.18430210355817	-1.69117900059955	5	2	0.00174064403829417	1149	7161	8454,9978	CUL1,RBX1
hsa_M00386	Cul4-DDB1-CSA complex	0.18430210355817	-1.69117900059955	5	2	0.00174064403829417	1149	7161	9978,1642	RBX1,DDB1
M00386	Cul4-DDB1-CSA complex	0.18430210355817	-1.69117900059955	5	2	0.00174064403829417	1149	7161	9978,1642	RBX1,DDB1
hsa_M00382	SCF-FBS complex	0.18430210355817	-1.69117900059955	5	2	0.00174064403829417	1149	7161	8454,9978	CUL1,RBX1
M00385	Cul4-DDB1-DDB2 complex	0.18430210355817	-1.69117900059955	5	2	0.00174064403829417	1149	7161	9978,1642	RBX1,DDB1
hsa_M00289	RF-C complex	0.18430210355817	-1.69117900059955	5	2	0.00174064403829417	1149	7161	5983,5982	RFC3,RFC2
hsa_M00383	ECV complex	0.18430210355817	-1.69117900059955	5	2	0.00174064403829417	1149	7161	9978,7428	RBX1,VHL
M00382	SCF-FBS complex	0.18430210355817	-1.69117900059955	5	2	0.00174064403829417	1149	7161	8454,9978	CUL1,RBX1
hsa01230	Biosynthesis of amino acids	0.198351925192991	-1.61771242602912	74	15	0.0130548302872063	1149	7161	27430,2806,3419,5634,1431,7086,3420,6888,5315,5832,5223,4548,4144,5214,587	MAT2B,GOT2,IDH3A,PRPS2,CS,TKT,IDH3B,TALDO1,PKM,ALDH18A1,PGAM1,MTR,MAT2A,PFKP,BCAT2
ko01230	Biosynthesis of amino acids	0.198351925192991	-1.61771242602912	74	15	0.0130548302872063	1149	7161	27430,2806,3419,5634,1431,7086,3420,6888,5315,5832,5223,4548,4144,5214,587	MAT2B,GOT2,IDH3A,PRPS2,CS,TKT,IDH3B,TALDO1,PKM,ALDH18A1,PGAM1,MTR,MAT2A,PFKP,BCAT2
hsa05164	Influenza A	0.203775449065996	-1.59073663126955	172	32	0.0278503046127067	1149	7161	23586,10625,8480,5894,54205,3661,3267,440275,3337,1432,5296,57506,10898,1386,29107,208,27102,7416,5605,355,5595,3304,3836,3716,5371,6772,3838,148022,60,6041,5594,55916	DDX58,IVNS1ABP,RAE1,RAF1,CYCS,IRF3,AGFG1,EIF2AK4,DNAJB1,MAPK14,PIK3R2,MAVS,CPSF4,ATF2,NXT1,AKT2,EIF2AK1,VDAC1,MAP2K2,FAS,MAPK3,HSPA1B,KPNA1,JAK1,PML,STAT1,KPNA2,TICAM1,ACTB,RNASEL,MAPK1,NXT2
ko05164	Influenza A	0.203775449065996	-1.59073663126955	172	32	0.0278503046127067	1149	7161	23586,10625,8480,5894,54205,3661,3267,440275,3337,1432,5296,57506,10898,1386,29107,208,27102,7416,5605,355,5595,3304,3836,3716,5371,6772,3838,148022,60,6041,5594,55916	DDX58,IVNS1ABP,RAE1,RAF1,CYCS,IRF3,AGFG1,EIF2AK4,DNAJB1,MAPK14,PIK3R2,MAVS,CPSF4,ATF2,NXT1,AKT2,EIF2AK1,VDAC1,MAP2K2,FAS,MAPK3,HSPA1B,KPNA1,JAK1,PML,STAT1,KPNA2,TICAM1,ACTB,RNASEL,MAPK1,NXT2
hsa00670	One carbon pool by folate	0.207346667537083	-1.57336316409923	20	5	0.00435161009573542	1149	7161	2618,200895,10797,4548,471	GART,DHFR2,MTHFD2,MTR,ATIC
ko00670	One carbon pool by folate	0.207346667537083	-1.57336316409923	20	5	0.00435161009573542	1149	7161	2618,10797,200895,4548,471	GART,MTHFD2,DHFR2,MTR,ATIC
M00152	Cytochrome bc1 complex	0.207526268516056	-1.57249735206579	10	3	0.00261096605744125	1149	7161	7388,1537,29796	UQCRH,CYC1,UQCR10
hsa_M00152	Cytochrome bc1 complex	0.207526268516056	-1.57249735206579	10	3	0.00261096605744125	1149	7161	7388,1537,29796	UQCRH,CYC1,UQCR10
M00413	FA core complex	0.207526268516056	-1.57249735206579	10	3	0.00261096605744125	1149	7161	55120,2178,80233	FANCL,FANCE,FAAP100
hsa_M00413	FA core complex	0.207526268516056	-1.57249735206579	10	3	0.00261096605744125	1149	7161	55120,2178,80233	FANCL,FANCE,FAAP100
hsa05224	Breast cancer	0.215159802026355	-1.53637426170043	144	27	0.0234986945169713	1149	7161	4893,208,5894,1871,23401,3845,4041,4853,672,1452,5605,8323,5595,5925,6464,5728,8312,81029,5296,1869,8313,8648,1855,5594,1870,3265,1856	NRAS,AKT2,RAF1,E2F3,FRAT2,KRAS,LRP5,NOTCH2,BRCA1,CSNK1A1,MAP2K2,FZD6,MAPK3,RB1,SHC1,PTEN,AXIN1,WNT5B,PIK3R2,E2F1,AXIN2,NCOA1,DVL1,MAPK1,E2F2,HRAS,DVL2
ko05224	Breast cancer	0.215159802026355	-1.53637426170043	144	27	0.0234986945169713	1149	7161	4893,208,5894,1871,23401,3845,4041,4853,672,1452,5605,8323,5595,5925,6464,5728,8312,81029,5296,1869,8313,8648,1855,5594,1870,3265,1856	NRAS,AKT2,RAF1,E2F3,FRAT2,KRAS,LRP5,NOTCH2,BRCA1,CSNK1A1,MAP2K2,FZD6,MAPK3,RB1,SHC1,PTEN,AXIN1,WNT5B,PIK3R2,E2F1,AXIN2,NCOA1,DVL1,MAPK1,E2F2,HRAS,DVL2
hsa01212	Fatty acid metabolism	0.232172570401484	-1.46027434588872	48	10	0.00870322019147084	1149	7161	51703,60481,5538,51,2181,3032,51102,38,34,9524	ACSL5,ELOVL5,PPT1,ACOX1,ACSL3,HADHB,MECR,ACAT1,ACADM,TECR
ko01212	Fatty acid metabolism	0.232172570401484	-1.46027434588872	48	10	0.00870322019147084	1149	7161	51703,60481,5538,51,2181,3032,51102,38,34,9524	ACSL5,ELOVL5,PPT1,ACOX1,ACSL3,HADHB,MECR,ACAT1,ACADM,TECR
hsa00562	Inositol phosphate metabolism	0.240665177798189	-1.42434861521067	71	14	0.0121845082680592	1149	7161	8897,5728,9110,3632,54928,79837,9107,9562,200576,10423,5305,3613,55361,23396	MTMR3,PTEN,MTMR4,INPP5A,IMPAD1,PIP4K2C,MTMR6,MINPP1,PIKFYVE,CDIPT,PIP4K2A,IMPA2,PI4K2A,PIP5K1C
ko00562	Inositol phosphate metabolism	0.240665177798189	-1.42434861521067	71	14	0.0121845082680592	1149	7161	8897,5728,9110,3632,54928,79837,9107,10423,200576,9562,5305,3613,23396,55361	MTMR3,PTEN,MTMR4,INPP5A,IMPAD1,PIP4K2C,MTMR6,CDIPT,PIKFYVE,MINPP1,PIP4K2A,IMPA2,PIP5K1C,PI4K2A
hsa00440	Phosphonate and phosphinate metabolism	0.248267072801157	-1.39325020580866	6	2	0.00174064403829417	1149	7161	5833,56994	PCYT2,CHPT1
hsa_M00085	Fatty acid biosynthesis, elongation, mitochondria	0.248267072801157	-1.39325020580866	6	2	0.00174064403829417	1149	7161	3032,51102	HADHB,MECR
hsa_M00285	MCM complex	0.248267072801157	-1.39325020580866	6	2	0.00174064403829417	1149	7161	4171,4174	MCM2,MCM5
hsa00750	Vitamin B6 metabolism	0.248267072801157	-1.39325020580866	6	2	0.00174064403829417	1149	7161	57026,8566	PDXP,PDXK
M00284	Origin recognition complex	0.248267072801157	-1.39325020580866	6	2	0.00174064403829417	1149	7161	4998,23595	ORC1,ORC3
ko00440	Phosphonate and phosphinate metabolism	0.248267072801157	-1.39325020580866	6	2	0.00174064403829417	1149	7161	5833,56994	PCYT2,CHPT1
hsa_M00284	Origin recognition complex	0.248267072801157	-1.39325020580866	6	2	0.00174064403829417	1149	7161	4998,23595	ORC1,ORC3
M00085	Fatty acid biosynthesis, elongation, mitochondria	0.248267072801157	-1.39325020580866	6	2	0.00174064403829417	1149	7161	3032,51102	HADHB,MECR
M00285	MCM complex	0.248267072801157	-1.39325020580866	6	2	0.00174064403829417	1149	7161	4171,4174	MCM2,MCM5
ko00750	Vitamin B6 metabolism	0.248267072801157	-1.39325020580866	6	2	0.00174064403829417	1149	7161	57026,8566	PDXP,PDXK
M00404	COPII complex	0.253424181207173	-1.37269058862676	11	3	0.00261096605744125	1149	7161	22872,56681,9632	SEC31A,SAR1A,SEC24C
hsa_M00404	COPII complex	0.253424181207173	-1.37269058862676	11	3	0.00261096605744125	1149	7161	22872,56681,9632	SEC31A,SAR1A,SEC24C
ko04520	Adherens junction	0.25784019990287	-1.35541526617712	72	14	0.0121845082680592	1149	7161	4301,10163,5792,387,4087,7454,998,5879,1457,60,5594,4089,56288,5595	AFDN,WASF2,PTPRF,RHOA,SMAD2,WAS,CDC42,RAC1,CSNK2A1,ACTB,MAPK1,SMAD4,PARD3,MAPK3
hsa04520	Adherens junction	0.25784019990287	-1.35541526617712	72	14	0.0121845082680592	1149	7161	4301,10163,5792,387,4087,7454,998,5879,1457,60,5594,4089,56288,5595	AFDN,WASF2,PTPRF,RHOA,SMAD2,WAS,CDC42,RAC1,CSNK2A1,ACTB,MAPK1,SMAD4,PARD3,MAPK3
hsa04916	Melanogenesis	0.259604313072117	-1.34859667999084	101	19	0.0165361183637946	1149	7161	4893,5894,3845,5566,5605,8323,5595,805,2778,81029,115,1855,1385,2771,5594,3265,818,1856,113	NRAS,RAF1,KRAS,PRKACA,MAP2K2,FZD6,MAPK3,CALM2,GNAS,WNT5B,ADCY9,DVL1,CREB1,GNAI2,MAPK1,HRAS,CAMK2G,DVL2,ADCY7
ko04916	Melanogenesis	0.259604313072117	-1.34859667999084	101	19	0.0165361183637946	1149	7161	4893,5894,3845,5566,5605,8323,5595,805,2778,81029,115,1855,1385,2771,5594,3265,818,1856,113	NRAS,RAF1,KRAS,PRKACA,MAP2K2,FZD6,MAPK3,CALM2,GNAS,WNT5B,ADCY9,DVL1,CREB1,GNAI2,MAPK1,HRAS,CAMK2G,DVL2,ADCY7
hsa05221	Acute myeloid leukemia	0.260089853523203	-1.34672811719538	55	11	0.00957354221061793	1149	7161	4893,5894,208,5296,5371,3845,5594,6774,3265,5605,5595	NRAS,RAF1,AKT2,PIK3R2,PML,KRAS,MAPK1,STAT3,HRAS,MAP2K2,MAPK3
ko05221	Acute myeloid leukemia	0.260089853523203	-1.34672811719538	55	11	0.00957354221061793	1149	7161	4893,5894,208,5296,5371,3845,5594,6774,3265,5605,5595	NRAS,RAF1,AKT2,PIK3R2,PML,KRAS,MAPK1,STAT3,HRAS,MAP2K2,MAPK3
ko04659	Th17 cell differentiation	0.262183432838052	-1.33871089485837	107	20	0.0174064403829417	1149	7161	7040,5530,4773,5532,3594,1432,50615,5595,6257,3662,4775,4087,3716,3572,6778,5534,6772,6774,5594,4089	TGFB1,PPP3CA,NFATC2,PPP3CB,IL12RB1,MAPK14,IL21R,MAPK3,RXRB,IRF4,NFATC3,SMAD2,JAK1,IL6ST,STAT6,PPP3R1,STAT1,STAT3,MAPK1,SMAD4
hsa04659	Th17 cell differentiation	0.262183432838052	-1.33871089485837	107	20	0.0174064403829417	1149	7161	7040,5530,4773,5532,3594,1432,50615,5595,6257,3662,4775,4087,3716,3572,6778,5534,6772,6774,5594,4089	TGFB1,PPP3CA,NFATC2,PPP3CB,IL12RB1,MAPK14,IL21R,MAPK3,RXRB,IRF4,NFATC3,SMAD2,JAK1,IL6ST,STAT6,PPP3R1,STAT1,STAT3,MAPK1,SMAD4
hsa02010	ABC transporters	0.266644657081667	-1.32183837933235	44	9	0.00783289817232376	1149	7161	21,89845,6890,215,6891,23456,19,10057,4363	ABCA3,ABCC10,TAP1,ABCD1,TAP2,ABCB10,ABCA1,ABCC5,ABCC1
ko02010	ABC transporters	0.266644657081667	-1.32183837933235	44	9	0.00783289817232376	1149	7161	21,89845,6890,215,23456,6891,19,10057,4363	ABCA3,ABCC10,TAP1,ABCD1,ABCB10,TAP2,ABCA1,ABCC5,ABCC1
ko05160	Hepatitis C	0.270017393034516	-1.3092689034122	131	24	0.02088772845953	1149	7161	23586,5170,4893,208,5894,3845,27102,3661,440275,1432,5595,5515,3716,5296,6772,148022,949,6041,57506,6774,5594,975,55844,3265	DDX58,PDPK1,NRAS,AKT2,RAF1,KRAS,EIF2AK1,IRF3,EIF2AK4,MAPK14,MAPK3,PPP2CA,JAK1,PIK3R2,STAT1,TICAM1,SCARB1,RNASEL,MAVS,STAT3,MAPK1,CD81,PPP2R2D,HRAS
hsa05160	Hepatitis C	0.270017393034516	-1.3092689034122	131	24	0.02088772845953	1149	7161	23586,5170,4893,208,5894,3845,27102,3661,440275,1432,5595,5515,3716,5296,6772,148022,949,6041,57506,6774,5594,975,55844,3265	DDX58,PDPK1,NRAS,AKT2,RAF1,KRAS,EIF2AK1,IRF3,EIF2AK4,MAPK14,MAPK3,PPP2CA,JAK1,PIK3R2,STAT1,TICAM1,SCARB1,RNASEL,MAVS,STAT3,MAPK1,CD81,PPP2R2D,HRAS
hsa04310	Wnt signaling pathway	0.27281486807566	-1.29896185275437	143	26	0.0226283724978242	1149	7161	5530,387,9978,5879,85409,23401,1457,8454,4773,4041,5532,1452,5663,5566,8323,80319,4775,6477,8312,81029,5534,8313,1855,4089,818,1856	PPP3CA,RHOA,RBX1,RAC1,NKD2,FRAT2,CSNK2A1,CUL1,NFATC2,LRP5,PPP3CB,CSNK1A1,PSEN1,PRKACA,FZD6,CXXC4,NFATC3,SIAH1,AXIN1,WNT5B,PPP3R1,AXIN2,DVL1,SMAD4,CAMK2G,DVL2
ko04310	Wnt signaling pathway	0.27281486807566	-1.29896185275437	143	26	0.0226283724978242	1149	7161	5530,387,9978,5879,85409,23401,1457,8454,4773,4041,5532,1452,5663,5566,8323,80319,4775,6477,8312,81029,5534,8313,1855,4089,818,1856	PPP3CA,RHOA,RBX1,RAC1,NKD2,FRAT2,CSNK2A1,CUL1,NFATC2,LRP5,PPP3CB,CSNK1A1,PSEN1,PRKACA,FZD6,CXXC4,NFATC3,SIAH1,AXIN1,WNT5B,PPP3R1,AXIN2,DVL1,SMAD4,CAMK2G,DVL2
ko04922	Glucagon signaling pathway	0.274434902734197	-1.29304119466601	102	19	0.0165361183637946	1149	7161	5530,5564,208,5562,6513,3939,5532,5315,5140,5566,2778,805,5534,1385,5223,1386,5261,818,3945	PPP3CA,PRKAB1,AKT2,PRKAA1,SLC2A1,LDHA,PPP3CB,PKM,PDE3B,PRKACA,GNAS,CALM2,PPP3R1,CREB1,PGAM1,ATF2,PHKG2,CAMK2G,LDHB
hsa04922	Glucagon signaling pathway	0.274434902734197	-1.29304119466601	102	19	0.0165361183637946	1149	7161	5530,5564,208,5562,6513,3939,5532,5315,5140,5566,2778,805,5534,1385,5223,1386,5261,818,3945	PPP3CA,PRKAB1,AKT2,PRKAA1,SLC2A1,LDHA,PPP3CB,PKM,PDE3B,PRKACA,GNAS,CALM2,PPP3R1,CREB1,PGAM1,ATF2,PHKG2,CAMK2G,LDHB
hsa04012	ErbB signaling pathway	0.28231433231638	-1.26473417520492	85	16	0.0139251523063534	1149	7161	4893,4690,5894,208,3845,2002,5605,5595,1399,27,6464,5296,1027,5594,3265,818	NRAS,NCK1,RAF1,AKT2,KRAS,ELK1,MAP2K2,MAPK3,CRKL,ABL2,SHC1,PIK3R2,CDKN1B,MAPK1,HRAS,CAMK2G
ko04012	ErbB signaling pathway	0.28231433231638	-1.26473417520492	85	16	0.0139251523063534	1149	7161	4893,4690,5894,208,3845,2002,5605,5595,27,1399,6464,5296,1027,5594,3265,818	NRAS,NCK1,RAF1,AKT2,KRAS,ELK1,MAP2K2,MAPK3,ABL2,CRKL,SHC1,PIK3R2,CDKN1B,MAPK1,HRAS,CAMK2G
ko05132	Salmonella infection	0.28231433231638	-1.26473417520492	85	16	0.0139251523063534	1149	7161	10163,391,7454,998,10092,7879,5879,4627,3831,60,6093,1432,10552,5594,1783,5595	WASF2,RHOG,WAS,CDC42,ARPC5,RAB7A,RAC1,MYH9,KLC1,ACTB,ROCK1,MAPK14,ARPC1A,MAPK1,DYNC1LI2,MAPK3
hsa05132	Salmonella infection	0.28231433231638	-1.26473417520492	85	16	0.0139251523063534	1149	7161	10163,391,7454,998,10092,7879,5879,4627,3831,60,6093,1432,10552,5594,1783,5595	WASF2,RHOG,WAS,CDC42,ARPC5,RAB7A,RAC1,MYH9,KLC1,ACTB,ROCK1,MAPK14,ARPC1A,MAPK1,DYNC1LI2,MAPK3
M00181	RNA polymerase III, eukaryotes	0.285770681170745	-1.25256560387544	17	4	0.00348128807658834	1149	7161	84265,5441,5440,51728	POLR3GL,POLR2L,POLR2K,POLR3K
hsa_M00181	RNA polymerase III, eukaryotes	0.285770681170745	-1.25256560387544	17	4	0.00348128807658834	1149	7161	84265,5441,5440,51728	POLR3GL,POLR2L,POLR2K,POLR3K
M00151	Cytochrome bc1 complex respiratory unit	0.29517872647529	-1.22017425363821	2	1	0.000870322019147084	1149	7161	1537	CYC1
hsa_M00554	Nucleotide sugar biosynthesis, galactose => UDP-galactose	0.29517872647529	-1.22017425363821	2	1	0.000870322019147084	1149	7161	2584	GALK1
M00293	DNA polymerase zeta  complex	0.29517872647529	-1.22017425363821	2	1	0.000870322019147084	1149	7161	10459	MAD2L2
hsa_M00151	Cytochrome bc1 complex respiratory unit	0.29517872647529	-1.22017425363821	2	1	0.000870322019147084	1149	7161	1537	CYC1
M00554	Nucleotide sugar biosynthesis, galactose => UDP-galactose	0.29517872647529	-1.22017425363821	2	1	0.000870322019147084	1149	7161	2584	GALK1
hsa_M00294	DNA polymerase gamma complex	0.29517872647529	-1.22017425363821	2	1	0.000870322019147084	1149	7161	11232	POLG2
hsa_M00293	DNA polymerase zeta  complex	0.29517872647529	-1.22017425363821	2	1	0.000870322019147084	1149	7161	10459	MAD2L2
M00294	DNA polymerase gamma complex	0.29517872647529	-1.22017425363821	2	1	0.000870322019147084	1149	7161	11232	POLG2
M00087	beta-Oxidation	0.300530346644509	-1.20220654293599	12	3	0.00261096605744125	1149	7161	34,51,3032	ACADM,ACOX1,HADHB
M00004	Pentose phosphate pathway (Pentose phosphate cycle)	0.300530346644509	-1.20220654293599	12	3	0.00261096605744125	1149	7161	2821,6888,7086	GPI,TALDO1,TKT
hsa_M00087	beta-Oxidation	0.300530346644509	-1.20220654293599	12	3	0.00261096605744125	1149	7161	34,51,3032	ACADM,ACOX1,HADHB
hsa_M00004	Pentose phosphate pathway (Pentose phosphate cycle)	0.300530346644509	-1.20220654293599	12	3	0.00261096605744125	1149	7161	2821,6888,7086	GPI,TALDO1,TKT
ko04912	GnRH signaling pathway	0.301365793738072	-1.19943049047763	92	17	0.0147954743255004	1149	7161	4893,5894,3845,2002,5566,1432,5605,5595,805,4216,2778,998,115,5594,3265,818,113	NRAS,RAF1,KRAS,ELK1,PRKACA,MAPK14,MAP2K2,MAPK3,CALM2,MAP3K4,GNAS,CDC42,ADCY9,MAPK1,HRAS,CAMK2G,ADCY7
hsa04912	GnRH signaling pathway	0.301365793738072	-1.19943049047763	92	17	0.0147954743255004	1149	7161	4893,5894,3845,2002,5566,1432,5605,5595,805,4216,2778,998,115,5594,3265,818,113	NRAS,RAF1,KRAS,ELK1,PRKACA,MAPK14,MAP2K2,MAPK3,CALM2,MAP3K4,GNAS,CDC42,ADCY9,MAPK1,HRAS,CAMK2G,ADCY7
hsa_M00007	Pentose phosphate pathway, non-oxidative phase, fructose 6P => ribose 5P	0.312720160461096	-1.16244654438329	7	2	0.00174064403829417	1149	7161	6888,7086	TALDO1,TKT
hsa_M00120	Coenzyme A biosynthesis, pantothenate => CoA	0.312720160461096	-1.16244654438329	7	2	0.00174064403829417	1149	7161	79717,60490	PPCS,PPCDC
hsa_M00691	DNA damage-induced cell cycle checkpoints	0.312720160461096	-1.16244654438329	7	2	0.00174064403829417	1149	7161	994,11200	CDC25B,CHEK2
M00691	DNA damage-induced cell cycle checkpoints	0.312720160461096	-1.16244654438329	7	2	0.00174064403829417	1149	7161	994,11200	CDC25B,CHEK2
hsa_M00396	Lsm 2-8 complex	0.312720160461096	-1.16244654438329	7	2	0.00174064403829417	1149	7161	51691,11157	LSM8,LSM6
M00396	Lsm 2-8 complex	0.312720160461096	-1.16244654438329	7	2	0.00174064403829417	1149	7161	51691,11157	LSM8,LSM6
M00007	Pentose phosphate pathway, non-oxidative phase, fructose 6P => ribose 5P	0.312720160461096	-1.16244654438329	7	2	0.00174064403829417	1149	7161	6888,7086	TALDO1,TKT
M00086	beta-Oxidation, acyl-CoA synthesis	0.312720160461096	-1.16244654438329	7	2	0.00174064403829417	1149	7161	51703,2181	ACSL5,ACSL3
M00120	Coenzyme A biosynthesis, pantothenate => CoA	0.312720160461096	-1.16244654438329	7	2	0.00174064403829417	1149	7161	79717,60490	PPCS,PPCDC
hsa_M00086	beta-Oxidation, acyl-CoA synthesis	0.312720160461096	-1.16244654438329	7	2	0.00174064403829417	1149	7161	51703,2181	ACSL5,ACSL3
hsa04530	Tight junction	0.312865799952195	-1.16198093452966	170	30	0.0261096605744125	1149	7161	55114,5564,387,5879,10096,5562,7430,4627,5566,8189,51735,140465,4301,5515,4218,7408,7454,3308,5906,5111,998,3688,9181,60,6794,6093,4217,55844,103910,56288	ARHGAP17,PRKAB1,RHOA,RAC1,ACTR3,PRKAA1,EZR,MYH9,PRKACA,SYMPK,RAPGEF6,MYL6B,AFDN,PPP2CA,RAB8A,VASP,WAS,HSPA4,RAP1A,PCNA,CDC42,ITGB1,ARHGEF2,ACTB,STK11,ROCK1,MAP3K5,PPP2R2D,MYL12B,PARD3
ko04530	Tight junction	0.312865799952195	-1.16198093452966	170	30	0.0261096605744125	1149	7161	55114,5564,387,5879,10096,5562,7430,4627,5566,8189,51735,140465,4301,5515,4218,7408,7454,3308,5906,5111,998,3688,9181,60,6794,6093,4217,55844,103910,56288	ARHGAP17,PRKAB1,RHOA,RAC1,ACTR3,PRKAA1,EZR,MYH9,PRKACA,SYMPK,RAPGEF6,MYL6B,AFDN,PPP2CA,RAB8A,VASP,WAS,HSPA4,RAP1A,PCNA,CDC42,ITGB1,ARHGEF2,ACTB,STK11,ROCK1,MAP3K5,PPP2R2D,MYL12B,PARD3
ko04062	Chemokine signaling pathway	0.313130780780912	-1.16113434573765	182	32	0.0278503046127067	1149	7161	387,4893,5894,208,5879,7410,2788,3845,4067,5566,2309,2783,5595,7409,1399,5906,7454,156,998,6464,9844,5296,115,6772,6093,6774,5594,2771,409,3265,56288,113	RHOA,NRAS,RAF1,AKT2,RAC1,VAV2,GNG7,KRAS,LYN,PRKACA,FOXO3,GNB2,MAPK3,VAV1,CRKL,RAP1A,WAS,GRK2,CDC42,SHC1,ELMO1,PIK3R2,ADCY9,STAT1,ROCK1,STAT3,MAPK1,GNAI2,ARRB2,HRAS,PARD3,ADCY7
hsa04062	Chemokine signaling pathway	0.313130780780912	-1.16113434573765	182	32	0.0278503046127067	1149	7161	387,4893,5894,208,5879,7410,2788,3845,4067,5566,2309,2783,5595,7409,1399,5906,7454,156,998,6464,9844,5296,115,6772,6093,6774,5594,2771,409,3265,56288,113	RHOA,NRAS,RAF1,AKT2,RAC1,VAV2,GNG7,KRAS,LYN,PRKACA,FOXO3,GNB2,MAPK3,VAV1,CRKL,RAP1A,WAS,GRK2,CDC42,SHC1,ELMO1,PIK3R2,ADCY9,STAT1,ROCK1,STAT3,MAPK1,GNAI2,ARRB2,HRAS,PARD3,ADCY7
hsa04064	NF-kappa B signaling pathway	0.334736212973394	-1.09441248129817	94	17	0.0147954743255004	1149	7161	23586,7128,330,23118,4616,331,1457,596,148022,598,9020,7329,7188,4067,329,23085,8837	DDX58,TNFAIP3,BIRC3,TAB2,GADD45B,XIAP,CSNK2A1,BCL2,TICAM1,BCL2L1,MAP3K14,UBE2I,TRAF5,LYN,BIRC2,ERC1,CFLAR
ko04064	NF-kappa B signaling pathway	0.334736212973394	-1.09441248129817	94	17	0.0147954743255004	1149	7161	23586,7128,330,23118,4616,331,1457,596,148022,598,9020,7329,7188,4067,329,23085,8837	DDX58,TNFAIP3,BIRC3,TAB2,GADD45B,XIAP,CSNK2A1,BCL2,TICAM1,BCL2L1,MAP3K14,UBE2I,TRAF5,LYN,BIRC2,ERC1,CFLAR
ko04961	Endocrine and other factor-regulated calcium reabsorption	0.337258821505251	-1.08690462706735	47	9	0.00783289817232376	1149	7161	2778,476,115,1785,163,1212,5566,1175,8766	GNAS,ATP1A1,ADCY9,DNM2,AP2B1,CLTB,PRKACA,AP2S1,RAB11A
hsa04961	Endocrine and other factor-regulated calcium reabsorption	0.337258821505251	-1.08690462706735	47	9	0.00783289817232376	1149	7161	2778,476,115,1785,163,1212,5566,1175,8766	GNAS,ATP1A1,ADCY9,DNM2,AP2B1,CLTB,PRKACA,AP2S1,RAB11A
ko05152	Tuberculosis	0.337397165075667	-1.08649451117093	178	31	0.0269799825935596	1149	7161	1263,7040,5530,387,208,5894,7879,8625,535,23365,54205,5532,1432,5869,8772,5595,805,533,1520,3716,6772,5534,1054,23545,596,527,11151,1385,5594,9114,818	PLK3,TGFB1,PPP3CA,RHOA,AKT2,RAF1,RAB7A,RFXANK,ATP6V0A1,ARHGEF12,CYCS,PPP3CB,MAPK14,RAB5B,FADD,MAPK3,CALM2,ATP6V0B,CTSS,JAK1,STAT1,PPP3R1,CEBPG,ATP6V0A2,BCL2,ATP6V0C,CORO1A,CREB1,MAPK1,ATP6V0D1,CAMK2G
hsa05152	Tuberculosis	0.337397165075667	-1.08649451117093	178	31	0.0269799825935596	1149	7161	1263,7040,5530,387,208,5894,7879,8625,535,23365,54205,5532,1432,5869,8772,5595,805,533,1520,3716,6772,5534,1054,23545,596,527,11151,1385,5594,9114,818	PLK3,TGFB1,PPP3CA,RHOA,AKT2,RAF1,RAB7A,RFXANK,ATP6V0A1,ARHGEF12,CYCS,PPP3CB,MAPK14,RAB5B,FADD,MAPK3,CALM2,ATP6V0B,CTSS,JAK1,STAT1,PPP3R1,CEBPG,ATP6V0A2,BCL2,ATP6V0C,CORO1A,CREB1,MAPK1,ATP6V0D1,CAMK2G
hsa04924	Renin secretion	0.346091636152047	-1.06105169461942	65	12	0.010443864229765	1149	7161	2778,805,5530,2983,5534,84876,154,5532,1385,5566,5140,2771	GNAS,CALM2,PPP3CA,GUCY1B1,PPP3R1,ORAI1,ADRB2,PPP3CB,CREB1,PRKACA,PDE3B,GNAI2
ko04924	Renin secretion	0.346091636152047	-1.06105169461942	65	12	0.010443864229765	1149	7161	2778,805,5530,2983,5534,84876,154,5532,1385,5566,5140,2771	GNAS,CALM2,PPP3CA,GUCY1B1,PPP3R1,ORAI1,ADRB2,PPP3CB,CREB1,PRKACA,PDE3B,GNAI2
M00036	Leucine degradation, leucine => acetoacetate + acetyl-CoA	0.347996282203877	-1.05556348258692	13	3	0.00261096605744125	1149	7161	34,587,56922	ACADM,BCAT2,MCCC1
hsa_M00036	Leucine degradation, leucine => acetoacetate + acetyl-CoA	0.347996282203877	-1.05556348258692	13	3	0.00261096605744125	1149	7161	34,587,56922	ACADM,BCAT2,MCCC1
hsa_M00676	PI3K-Akt signaling	0.347996282203877	-1.05556348258692	13	3	0.00261096605744125	1149	7161	2309,208,5296	FOXO3,AKT2,PIK3R2
hsa_M00050	Guanine ribonucleotide biosynthesis IMP => GDP,GTP	0.347996282203877	-1.05556348258692	13	3	0.00261096605744125	1149	7161	3614,5315,2987	IMPDH1,PKM,GUK1
M00050	Guanine ribonucleotide biosynthesis IMP => GDP,GTP	0.347996282203877	-1.05556348258692	13	3	0.00261096605744125	1149	7161	3614,5315,2987	IMPDH1,PKM,GUK1
M00676	PI3K-Akt signaling	0.347996282203877	-1.05556348258692	13	3	0.00261096605744125	1149	7161	2309,208,5296	FOXO3,AKT2,PIK3R2
hsa05145	Toxoplasmosis	0.352637558519132	-1.04231449591874	113	20	0.0174064403829417	1149	7161	5170,7040,10105,330,208,331,54205,598,1432,329,3304,5595,3716,23118,3688,6772,596,6774,5594,2771	PDPK1,TGFB1,PPIF,BIRC3,AKT2,XIAP,CYCS,BCL2L1,MAPK14,BIRC2,HSPA1B,MAPK3,JAK1,TAB2,ITGB1,STAT1,BCL2,STAT3,MAPK1,GNAI2
ko05145	Toxoplasmosis	0.352637558519132	-1.04231449591874	113	20	0.0174064403829417	1149	7161	5170,7040,10105,330,208,331,54205,598,1432,329,3304,5595,3716,23118,3688,6772,596,6774,5594,2771	PDPK1,TGFB1,PPIF,BIRC3,AKT2,XIAP,CYCS,BCL2L1,MAPK14,BIRC2,HSPA1B,MAPK3,JAK1,TAB2,ITGB1,STAT1,BCL2,STAT3,MAPK1,GNAI2
hsa00280	Valine, leucine and isoleucine degradation	0.361509494836317	-1.01746697262086	48	9	0.00783289817232376	1149	7161	38,34,27034,4594,65985,223,3032,587,56922	ACAT1,ACADM,ACAD8,MUT,AACS,ALDH9A1,HADHB,BCAT2,MCCC1
ko00280	Valine, leucine and isoleucine degradation	0.361509494836317	-1.01746697262086	48	9	0.00783289817232376	1149	7161	38,34,27034,4594,65985,223,3032,587,56922	ACAT1,ACADM,ACAD8,MUT,AACS,ALDH9A1,HADHB,BCAT2,MCCC1
hsa04360	Axon guidance	0.362961708653178	-1.01345793608522	174	30	0.0261096605744125	1149	7161	5530,387,4893,10154,4690,5894,5879,23365,4773,3845,5532,5361,5595,1020,4775,998,3984,81029,1808,5296,3688,5534,5781,6093,5594,2771,3265,818,56288,1072	PPP3CA,RHOA,NRAS,PLXNC1,NCK1,RAF1,RAC1,ARHGEF12,NFATC2,KRAS,PPP3CB,PLXNA1,MAPK3,CDK5,NFATC3,CDC42,LIMK1,WNT5B,DPYSL2,PIK3R2,ITGB1,PPP3R1,PTPN11,ROCK1,MAPK1,GNAI2,HRAS,CAMK2G,PARD3,CFL1
ko04360	Axon guidance	0.362961708653178	-1.01345793608522	174	30	0.0261096605744125	1149	7161	5530,387,4893,10154,4690,5894,5879,23365,4773,3845,5532,5361,5595,1020,4775,998,3984,81029,1808,5296,3688,5534,5781,6093,5594,2771,3265,818,56288,1072	PPP3CA,RHOA,NRAS,PLXNC1,NCK1,RAF1,RAC1,ARHGEF12,NFATC2,KRAS,PPP3CB,PLXNA1,MAPK3,CDK5,NFATC3,CDC42,LIMK1,WNT5B,DPYSL2,PIK3R2,ITGB1,PPP3R1,PTPN11,ROCK1,MAPK1,GNAI2,HRAS,CAMK2G,PARD3,CFL1
hsa04923	Regulation of lipolysis in adipocytes	0.363842544220959	-1.01103407575269	54	10	0.00870322019147084	1149	7161	2778,208,5296,115,154,5566,5140,2771,51099,113	GNAS,AKT2,PIK3R2,ADCY9,ADRB2,PRKACA,PDE3B,GNAI2,ABHD5,ADCY7
hsa04371	Apelin signaling pathway	0.366674449744505	-1.00328088251314	138	24	0.02088772845953	1149	7161	5564,4893,208,5894,2788,5562,4205,3845,4209,8678,5140,5566,2783,5605,5595,805,4899,4087,115,2771,5594,4089,3265,113	PRKAB1,NRAS,AKT2,RAF1,GNG7,PRKAA1,MEF2A,KRAS,MEF2D,BECN1,PDE3B,PRKACA,GNB2,MAP2K2,MAPK3,CALM2,NRF1,SMAD2,ADCY9,GNAI2,MAPK1,SMAD4,HRAS,ADCY7
ko04350	TGF-beta signaling pathway	0.368676673864265	-0.997835241639083	84	15	0.0130548302872063	1149	7161	7040,5515,387,4087,5933,9978,1874,7027,8454,6093,4086,5594,57154,4089,5595	TGFB1,PPP2CA,RHOA,SMAD2,RBL1,RBX1,E2F4,TFDP1,CUL1,ROCK1,SMAD1,MAPK1,SMURF1,SMAD4,MAPK3
hsa04350	TGF-beta signaling pathway	0.368676673864265	-0.997835241639083	84	15	0.0130548302872063	1149	7161	7040,5515,387,4087,5933,9978,1874,7027,8454,6093,4086,5594,57154,4089,5595	TGFB1,PPP2CA,RHOA,SMAD2,RBL1,RBX1,E2F4,TFDP1,CUL1,ROCK1,SMAD1,MAPK1,SMURF1,SMAD4,MAPK3
hsa_M00001	Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate	0.373022366825567	-0.986116896456327	25	5	0.00435161009573542	1149	7161	83440,2821,5315,5223,5214	ADPGK,GPI,PKM,PGAM1,PFKP
hsa00563	Glycosylphosphatidylinositol (GPI)-anchor biosynthesis	0.373022366825567	-0.986116896456327	25	5	0.00435161009573542	1149	7161	93183,23556,51604,9091,54872	PIGM,PIGN,PIGT,PIGQ,PIGG
M00001	Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate	0.373022366825567	-0.986116896456327	25	5	0.00435161009573542	1149	7161	83440,2821,5315,5223,5214	ADPGK,GPI,PKM,PGAM1,PFKP
hsa00062	Fatty acid elongation	0.373022366825567	-0.986116896456327	25	5	0.00435161009573542	1149	7161	60481,9524,5538,3032,51102	ELOVL5,TECR,PPT1,HADHB,MECR
ko00563	Glycosylphosphatidylinositol (GPI)-anchor biosynthesis	0.373022366825567	-0.986116896456327	25	5	0.00435161009573542	1149	7161	93183,23556,51604,9091,54872	PIGM,PIGN,PIGT,PIGQ,PIGG
ko00062	Fatty acid elongation	0.373022366825567	-0.986116896456327	25	5	0.00435161009573542	1149	7161	60481,9524,5538,3032,51102	ELOVL5,TECR,PPT1,HADHB,MECR
ko00740	Riboflavin metabolism	0.375859380555125	-0.978540193428459	8	2	0.00174064403829417	1149	7161	80308,53	FLAD1,ACP2
M00065	GPI-anchor biosynthesis, core oligosaccharide	0.375859380555125	-0.978540193428459	8	2	0.00174064403829417	1149	7161	93183,23556	PIGM,PIGN
hsa00740	Riboflavin metabolism	0.375859380555125	-0.978540193428459	8	2	0.00174064403829417	1149	7161	80308,53	FLAD1,ACP2
hsa_M00065	GPI-anchor biosynthesis, core oligosaccharide	0.375859380555125	-0.978540193428459	8	2	0.00174064403829417	1149	7161	93183,23556	PIGM,PIGN
ko00052	Galactose metabolism	0.37853768840946	-0.97143963798519	31	6	0.00522193211488251	1149	7161	2683,231,2584,7360,5214,8704	B4GALT1,AKR1B1,GALK1,UGP2,PFKP,B4GALT2
ko01523	Antifolate resistance	0.37853768840946	-0.97143963798519	31	6	0.00522193211488251	1149	7161	6573,2618,200895,471,4363,10057	SLC19A1,GART,DHFR2,ATIC,ABCC1,ABCC5
ko00512	Mucin type O-glycan biosynthesis	0.37853768840946	-0.97143963798519	31	6	0.00522193211488251	1149	7161	56913,6483,2590,55568,51809,9334	C1GALT1,ST3GAL2,GALNT2,GALNT10,GALNT7,B4GALT5
hsa00512	Mucin type O-glycan biosynthesis	0.37853768840946	-0.97143963798519	31	6	0.00522193211488251	1149	7161	56913,6483,2590,55568,51809,9334	C1GALT1,ST3GAL2,GALNT2,GALNT10,GALNT7,B4GALT5
hsa00052	Galactose metabolism	0.37853768840946	-0.97143963798519	31	6	0.00522193211488251	1149	7161	231,2683,2584,7360,5214,8704	AKR1B1,B4GALT1,GALK1,UGP2,PFKP,B4GALT2
hsa01523	Antifolate resistance	0.37853768840946	-0.97143963798519	31	6	0.00522193211488251	1149	7161	6573,2618,200895,471,4363,10057	SLC19A1,GART,DHFR2,ATIC,ABCC1,ABCC5
ko00330	Arginine and proline metabolism	0.385946318427255	-0.952056990620615	49	9	0.00783289817232376	1149	7161	6723,5832,4942,4953,51056,2806,112483,262,223	SRM,ALDH18A1,OAT,ODC1,LAP3,GOT2,SAT2,AMD1,ALDH9A1
hsa00330	Arginine and proline metabolism	0.385946318427255	-0.952056990620615	49	9	0.00783289817232376	1149	7161	6723,5832,4942,4953,51056,2806,112483,262,223	SRM,ALDH18A1,OAT,ODC1,LAP3,GOT2,SAT2,AMD1,ALDH9A1
hsa04070	Phosphatidylinositol signaling system	0.386226838116222	-0.951330418610359	97	17	0.0147954743255004	1149	7161	8760,79837,9107,51447,10423,5305,55361,23396,805,8897,3632,9110,5728,54928,5296,200576,3613	CDS2,PIP4K2C,MTMR6,IP6K2,CDIPT,PIP4K2A,PI4K2A,PIP5K1C,CALM2,MTMR3,INPP5A,MTMR4,PTEN,IMPAD1,PIK3R2,PIKFYVE,IMPA2
ko04070	Phosphatidylinositol signaling system	0.386226838116222	-0.951330418610359	97	17	0.0147954743255004	1149	7161	8760,79837,9107,51447,10423,5305,55361,23396,805,8897,3632,9110,5728,54928,5296,200576,3613	CDS2,PIP4K2C,MTMR6,IP6K2,CDIPT,PIP4K2A,PI4K2A,PIP5K1C,CALM2,MTMR3,INPP5A,MTMR4,PTEN,IMPAD1,PIK3R2,PIKFYVE,IMPA2
M00400	p97-Ufd1-Npl4 complex	0.408300621055039	-0.895751559582478	3	1	0.000870322019147084	1149	7161	55666	NPLOC4
hsa_M00400	p97-Ufd1-Npl4 complex	0.408300621055039	-0.895751559582478	3	1	0.000870322019147084	1149	7161	55666	NPLOC4
hsa_M00410	ESCRT-II complex	0.408300621055039	-0.895751559582478	3	1	0.000870322019147084	1149	7161	84313	VPS25
hsa_M00134	Polyamine biosynthesis, arginine => ornithine => putrescine	0.408300621055039	-0.895751559582478	3	1	0.000870322019147084	1149	7161	4953	ODC1
M00005	PRPP biosynthesis, ribose 5P => PRPP	0.408300621055039	-0.895751559582478	3	1	0.000870322019147084	1149	7161	5634	PRPS2
M00410	ESCRT-II complex	0.408300621055039	-0.895751559582478	3	1	0.000870322019147084	1149	7161	84313	VPS25
M00134	Polyamine biosynthesis, arginine => ornithine => putrescine	0.408300621055039	-0.895751559582478	3	1	0.000870322019147084	1149	7161	4953	ODC1
hsa_M00118	Glutathione biosynthesis, glutamate => glutathione	0.408300621055039	-0.895751559582478	3	1	0.000870322019147084	1149	7161	2730	GCLM
M00118	Glutathione biosynthesis, glutamate => glutathione	0.408300621055039	-0.895751559582478	3	1	0.000870322019147084	1149	7161	2730	GCLM
hsa_M00005	PRPP biosynthesis, ribose 5P => PRPP	0.408300621055039	-0.895751559582478	3	1	0.000870322019147084	1149	7161	5634	PRPS2
ko04933	AGE-RAGE signaling pathway in diabetic complications	0.421100012982971	-0.864884912983167	99	17	0.0147954743255004	1149	7161	7040,4893,208,5879,3845,1432,5595,4087,998,5296,6772,1027,596,6774,5594,3265,4089	TGFB1,NRAS,AKT2,RAC1,KRAS,MAPK14,MAPK3,SMAD2,CDC42,PIK3R2,STAT1,CDKN1B,BCL2,STAT3,MAPK1,HRAS,SMAD4
hsa04933	AGE-RAGE signaling pathway in diabetic complications	0.421100012982971	-0.864884912983167	99	17	0.0147954743255004	1149	7161	7040,4893,208,5879,3845,1432,5595,4087,998,5296,6772,1027,596,6774,5594,3265,4089	TGFB1,NRAS,AKT2,RAC1,KRAS,MAPK14,MAPK3,SMAD2,CDC42,PIK3R2,STAT1,CDKN1B,BCL2,STAT3,MAPK1,HRAS,SMAD4
hsa_M00135	GABA biosynthesis, eukaryotes, putrescine => GABA	0.436447610209044	-0.829086933336347	9	2	0.00174064403829417	1149	7161	112483,223	SAT2,ALDH9A1
hsa_M00361	Nucleotide sugar biosynthesis, eukaryotes	0.436447610209044	-0.829086933336347	9	2	0.00174064403829417	1149	7161	7360,6675	UGP2,UAP1
M00361	Nucleotide sugar biosynthesis, eukaryotes	0.436447610209044	-0.829086933336347	9	2	0.00174064403829417	1149	7161	7360,6675	UGP2,UAP1
M00135	GABA biosynthesis, eukaryotes, putrescine => GABA	0.436447610209044	-0.829086933336347	9	2	0.00174064403829417	1149	7161	112483,223	SAT2,ALDH9A1
hsa03022	Basal transcription factors	0.436735449810324	-0.828427645210213	45	8	0.00696257615317668	1149	7161	6873,9519,27097,10629,6883,2966,6878,2962	TAF2,TBPL1,TAF5L,TAF6L,TAF12,GTF2H2,TAF6,GTF2F1
ko03022	Basal transcription factors	0.436735449810324	-0.828427645210213	45	8	0.00696257615317668	1149	7161	6873,9519,27097,10629,6883,2966,6878,2962	TAF2,TBPL1,TAF5L,TAF6L,TAF12,GTF2H2,TAF6,GTF2F1
hsa00603	Glycosphingolipid biosynthesis - globo and isoglobo series	0.441240206868378	-0.818165865046922	15	3	0.00261096605744125	1149	7161	6483,3073,3074	ST3GAL2,HEXA,HEXB
hsa00604	Glycosphingolipid biosynthesis - ganglio series	0.441240206868378	-0.818165865046922	15	3	0.00261096605744125	1149	7161	6483,3073,3074	ST3GAL2,HEXA,HEXB
ko00604	Glycosphingolipid biosynthesis - ganglio series	0.441240206868378	-0.818165865046922	15	3	0.00261096605744125	1149	7161	6483,3073,3074	ST3GAL2,HEXA,HEXB
hsa04540	Gap junction	0.443122162572422	-0.81390978493786	88	15	0.0130548302872063	1149	7161	2778,4893,2983,5894,115,3845,5594,2771,5566,3265,5605,1453,203068,5595,113	GNAS,NRAS,GUCY1B1,RAF1,ADCY9,KRAS,MAPK1,GNAI2,PRKACA,HRAS,MAP2K2,CSNK1D,TUBB,MAPK3,ADCY7
ko04540	Gap junction	0.443122162572422	-0.81390978493786	88	15	0.0130548302872063	1149	7161	2778,4893,2983,5894,115,3845,5594,2771,5566,3265,5605,1453,203068,5595,113	GNAS,NRAS,GUCY1B1,RAF1,ADCY9,KRAS,MAPK1,GNAI2,PRKACA,HRAS,MAP2K2,CSNK1D,TUBB,MAPK3,ADCY7
hsa04622	RIG-I-like receptor signaling pathway	0.450635502391261	-0.797096464937095	70	12	0.010443864229765	1149	7161	55593,23586,1540,5300,10010,80143,3661,57506,64343,1432,8772,9636	OTUD5,DDX58,CYLD,PIN1,TANK,SIKE1,IRF3,MAVS,AZI2,MAPK14,FADD,ISG15
ko04622	RIG-I-like receptor signaling pathway	0.450635502391261	-0.797096464937095	70	12	0.010443864229765	1149	7161	55593,23586,1540,5300,10010,80143,3661,57506,64343,1432,8772,9636	OTUD5,DDX58,CYLD,PIN1,TANK,SIKE1,IRF3,MAVS,AZI2,MAPK14,FADD,ISG15
hsa04066	HIF-1 signaling pathway	0.456083921796105	-0.785078447374309	101	17	0.0147954743255004	1149	7161	9978,208,7428,6513,3939,5209,5605,7037,5595,8569,5296,1027,596,5594,6774,818,54583	RBX1,AKT2,VHL,SLC2A1,LDHA,PFKFB3,MAP2K2,TFRC,MAPK3,MKNK1,PIK3R2,CDKN1B,BCL2,MAPK1,STAT3,CAMK2G,EGLN1
hsa04650	Natural killer cell mediated cytotoxicity	0.459113204229117	-0.778458467022895	132	22	0.0191470844212359	1149	7161	5530,4893,5894,3133,5879,7410,4773,3845,5532,3384,5605,3105,5595,355,7409,3106,6464,5296,5534,5781,5594,3265	PPP3CA,NRAS,RAF1,HLA-E,RAC1,VAV2,NFATC2,KRAS,PPP3CB,ICAM2,MAP2K2,HLA-A,MAPK3,FAS,VAV1,HLA-B,SHC1,PIK3R2,PPP3R1,PTPN11,MAPK1,HRAS
ko04650	Natural killer cell mediated cytotoxicity	0.459113204229117	-0.778458467022895	132	22	0.0191470844212359	1149	7161	5530,4893,5894,3133,5879,7410,4773,3845,5532,3384,5605,3105,5595,355,7409,3106,6464,5296,5534,5781,5594,3265	PPP3CA,NRAS,RAF1,HLA-E,RAC1,VAV2,NFATC2,KRAS,PPP3CB,ICAM2,MAP2K2,HLA-A,MAPK3,FAS,VAV1,HLA-B,SHC1,PIK3R2,PPP3R1,PTPN11,MAPK1,HRAS
ko04130	SNARE interactions in vesicular transport	0.470291420448718	-0.754402732917675	34	6	0.00522193211488251	1149	7161	8675,9527,9342,8773,53407,143187	STX16,GOSR1,SNAP29,SNAP23,STX18,VTI1A
hsa04130	SNARE interactions in vesicular transport	0.470291420448718	-0.754402732917675	34	6	0.00522193211488251	1149	7161	8675,9527,9342,8773,53407,143187	STX16,GOSR1,SNAP29,SNAP23,STX18,VTI1A
M00689	MAPK (p38) signaling	0.479835670724418	-0.734311586353713	22	4	0.00348128807658834	1149	7161	4216,4217,1432,57551	MAP3K4,MAP3K5,MAPK14,TAOK1
hsa_M00689	MAPK (p38) signaling	0.479835670724418	-0.734311586353713	22	4	0.00348128807658834	1149	7161	4216,4217,1432,57551	MAP3K4,MAP3K5,MAPK14,TAOK1
hsa_M00681	Activin signaling	0.493677945629814	-0.705871906317691	10	2	0.00174064403829417	1149	7161	4087,4089	SMAD2,SMAD4
hsa_M00095	C5 isoprenoid biosynthesis, mevalonate pathway	0.493677945629814	-0.705871906317691	10	2	0.00174064403829417	1149	7161	38,10654	ACAT1,PMVK
ko00920	Sulfur metabolism	0.493677945629814	-0.705871906317691	10	2	0.00174064403829417	1149	7161	54205,54928	CYCS,IMPAD1
M00681	Activin signaling	0.493677945629814	-0.705871906317691	10	2	0.00174064403829417	1149	7161	4087,4089	SMAD2,SMAD4
hsa00072	Synthesis and degradation of ketone bodies	0.493677945629814	-0.705871906317691	10	2	0.00174064403829417	1149	7161	38,622	ACAT1,BDH1
M00095	C5 isoprenoid biosynthesis, mevalonate pathway	0.493677945629814	-0.705871906317691	10	2	0.00174064403829417	1149	7161	38,10654	ACAT1,PMVK
hsa00920	Sulfur metabolism	0.493677945629814	-0.705871906317691	10	2	0.00174064403829417	1149	7161	54205,54928	CYCS,IMPAD1
ko00072	Synthesis and degradation of ketone bodies	0.493677945629814	-0.705871906317691	10	2	0.00174064403829417	1149	7161	38,622	ACAT1,BDH1
ko05020	Prion diseases	0.500140140525468	-0.692866938780406	35	6	0.00522193211488251	1149	7161	2002,5594,5566,5605,5595,5621	ELK1,MAPK1,PRKACA,MAP2K2,MAPK3,PRNP
hsa05020	Prion diseases	0.500140140525468	-0.692866938780406	35	6	0.00522193211488251	1149	7161	2002,5594,5566,5605,5595,5621	ELK1,MAPK1,PRKACA,MAP2K2,MAPK3,PRNP
M00632	Galactose degradation, Leloir pathway, galactose => alpha-D-glucose-1P	0.503280026813802	-0.686608550442264	4	1	0.000870322019147084	1149	7161	2584	GALK1
hsa_M00263	DNA polymerase epsilon complex	0.503280026813802	-0.686608550442264	4	1	0.000870322019147084	1149	7161	5426	POLE
hsa00290	Valine, leucine and isoleucine biosynthesis	0.503280026813802	-0.686608550442264	4	1	0.000870322019147084	1149	7161	587	BCAT2
hsa_M00741	Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA	0.503280026813802	-0.686608550442264	4	1	0.000870322019147084	1149	7161	4594	MUT
M00015	Proline biosynthesis, glutamate => proline	0.503280026813802	-0.686608550442264	4	1	0.000870322019147084	1149	7161	5832	ALDH18A1
ko00471	D-Glutamine and D-glutamate metabolism	0.503280026813802	-0.686608550442264	4	1	0.000870322019147084	1149	7161	2746	GLUD1
hsa00471	D-Glutamine and D-glutamate metabolism	0.503280026813802	-0.686608550442264	4	1	0.000870322019147084	1149	7161	2746	GLUD1
ko00290	Valine, leucine and isoleucine biosynthesis	0.503280026813802	-0.686608550442264	4	1	0.000870322019147084	1149	7161	587	BCAT2
hsa_M00425	H/ACA ribonucleoprotein complex	0.503280026813802	-0.686608550442264	4	1	0.000870322019147084	1149	7161	54433	GAR1
hsa_M00015	Proline biosynthesis, glutamate => proline	0.503280026813802	-0.686608550442264	4	1	0.000870322019147084	1149	7161	5832	ALDH18A1
hsa_M00632	Galactose degradation, Leloir pathway, galactose => alpha-D-glucose-1P	0.503280026813802	-0.686608550442264	4	1	0.000870322019147084	1149	7161	2584	GALK1
M00263	DNA polymerase epsilon complex	0.503280026813802	-0.686608550442264	4	1	0.000870322019147084	1149	7161	5426	POLE
M00741	Propanoyl-CoA metabolism, propanoyl-CoA => succinyl-CoA	0.503280026813802	-0.686608550442264	4	1	0.000870322019147084	1149	7161	4594	MUT
M00425	H/ACA ribonucleoprotein complex	0.503280026813802	-0.686608550442264	4	1	0.000870322019147084	1149	7161	54433	GAR1
hsa04510	Focal adhesion	0.512708137111024	-0.668048529222222	198	32	0.0278503046127067	1149	7161	4659,5894,5879,7410,331,3693,329,23396,7409,1399,824,7408,5906,6464,3696,998,5728,5296,54776,596,5170,387,330,208,2002,5595,3688,60,6093,5594,103910,3265	PPP1R12A,RAF1,RAC1,VAV2,XIAP,ITGB5,BIRC2,PIP5K1C,VAV1,CRKL,CAPN2,VASP,RAP1A,SHC1,ITGB8,CDC42,PTEN,PIK3R2,PPP1R12C,BCL2,PDPK1,RHOA,BIRC3,AKT2,ELK1,MAPK3,ITGB1,ACTB,ROCK1,MAPK1,MYL12B,HRAS
ko04510	Focal adhesion	0.512708137111024	-0.668048529222222	198	32	0.0278503046127067	1149	7161	4659,5894,5879,7410,331,3693,329,23396,7409,1399,824,7408,5906,6464,3696,998,5728,5296,54776,596,5170,387,330,208,2002,5595,3688,60,6093,5594,103910,3265	PPP1R12A,RAF1,RAC1,VAV2,XIAP,ITGB5,BIRC2,PIP5K1C,VAV1,CRKL,CAPN2,VASP,RAP1A,SHC1,ITGB8,CDC42,PTEN,PIK3R2,PPP1R12C,BCL2,PDPK1,RHOA,BIRC3,AKT2,ELK1,MAPK3,ITGB1,ACTB,ROCK1,MAPK1,MYL12B,HRAS
ko00515	Mannose type O-glycan biosynthesis	0.516690219577321	-0.660311772497291	23	4	0.00348128807658834	1149	7161	2683,10329,8703,8704	B4GALT1,RXYLT1,B4GALT3,B4GALT2
hsa00515	Mannose type O-glycan biosynthesis	0.516690219577321	-0.660311772497291	23	4	0.00348128807658834	1149	7161	2683,10329,8703,8704	B4GALT1,RXYLT1,B4GALT3,B4GALT2
ko04658	Th1 and Th2 cell differentiation	0.517151423601583	-0.659419558379395	92	15	0.0130548302872063	1149	7161	5530,4775,3716,6778,6772,5534,4773,4853,3594,3516,5532,9794,1432,5594,5595	PPP3CA,NFATC3,JAK1,STAT6,STAT1,PPP3R1,NFATC2,NOTCH2,IL12RB1,RBPJ,PPP3CB,MAML1,MAPK14,MAPK1,MAPK3
hsa04658	Th1 and Th2 cell differentiation	0.517151423601583	-0.659419558379395	92	15	0.0130548302872063	1149	7161	5530,4775,3716,6778,6772,5534,4773,4853,3594,3516,5532,9794,1432,5594,5595	PPP3CA,NFATC3,JAK1,STAT6,STAT1,PPP3R1,NFATC2,NOTCH2,IL12RB1,RBPJ,PPP3CB,MAML1,MAPK14,MAPK1,MAPK3
hsa00360	Phenylalanine metabolism	0.528836103367081	-0.637076718631737	17	3	0.00261096605744125	1149	7161	4282,221,2806	MIF,ALDH3B1,GOT2
ko00360	Phenylalanine metabolism	0.528836103367081	-0.637076718631737	17	3	0.00261096605744125	1149	7161	4282,221,2806	MIF,ALDH3B1,GOT2
ko00030	Pentose phosphate pathway	0.53948674792292	-0.61713705821322	30	5	0.00435161009573542	1149	7161	2821,6888,5634,5214,7086	GPI,TALDO1,PRPS2,PFKP,TKT
hsa00030	Pentose phosphate pathway	0.53948674792292	-0.61713705821322	30	5	0.00435161009573542	1149	7161	2821,6888,5634,5214,7086	GPI,TALDO1,PRPS2,PFKP,TKT
hsa04621	NOD-like receptor signaling pathway	0.543009532265244	-0.610628404385998	169	27	0.0234986945169713	1149	7161	387,7295,330,7128,140609,7417,331,55914,3661,598,7416,1432,329,8772,5595,9927,3716,23118,10010,6772,148022,596,57506,6041,5594,7188,3428	RHOA,TXN,BIRC3,TNFAIP3,NEK7,VDAC2,XIAP,ERBIN,IRF3,BCL2L1,VDAC1,MAPK14,BIRC2,FADD,MAPK3,MFN2,JAK1,TAB2,TANK,STAT1,TICAM1,BCL2,MAVS,RNASEL,MAPK1,TRAF5,IFI16
ko04621	NOD-like receptor signaling pathway	0.543009532265244	-0.610628404385998	169	27	0.0234986945169713	1149	7161	387,7295,330,7128,140609,7417,331,55914,3661,598,7416,1432,329,8772,5595,9927,3716,23118,10010,6772,148022,596,57506,6041,5594,7188,3428	RHOA,TXN,BIRC3,TNFAIP3,NEK7,VDAC2,XIAP,ERBIN,IRF3,BCL2L1,VDAC1,MAPK14,BIRC2,FADD,MAPK3,MFN2,JAK1,TAB2,TANK,STAT1,TICAM1,BCL2,MAVS,RNASEL,MAPK1,TRAF5,IFI16
ko04261	Adrenergic signaling in cardiomyocytes	0.545399790778744	-0.606236192181387	144	23	0.0200174064403829	1149	7161	208,154,3784,1432,5566,5595,1390,2778,5515,805,782,476,5525,488,115,596,1385,5594,1386,2771,55844,818,113	AKT2,ADRB2,KCNQ1,MAPK14,PRKACA,MAPK3,CREM,GNAS,PPP2CA,CALM2,CACNB1,ATP1A1,PPP2R5A,ATP2A2,ADCY9,BCL2,CREB1,MAPK1,ATF2,GNAI2,PPP2R2D,CAMK2G,ADCY7
hsa04261	Adrenergic signaling in cardiomyocytes	0.545399790778744	-0.606236192181387	144	23	0.0200174064403829	1149	7161	208,154,3784,1432,5566,5595,1390,2778,5515,805,782,476,5525,488,115,596,1385,5594,1386,2771,55844,818,113	AKT2,ADRB2,KCNQ1,MAPK14,PRKACA,MAPK3,CREM,GNAS,PPP2CA,CALM2,CACNB1,ATP1A1,PPP2R5A,ATP2A2,ADCY9,BCL2,CREB1,MAPK1,ATF2,GNAI2,PPP2R2D,CAMK2G,ADCY7
ko00130	Ubiquinone and other terpenoid-quinone biosynthesis	0.547067671060098	-0.60318277112223	11	2	0.00174064403829417	1149	7161	79001,1728	VKORC1,NQO1
M00101	Cholesterol biosynthesis, squalene 2,3-epoxide => cholesterol	0.547067671060098	-0.60318277112223	11	2	0.00174064403829417	1149	7161	50814,10682	NSDHL,EBP
hsa00130	Ubiquinone and other terpenoid-quinone biosynthesis	0.547067671060098	-0.60318277112223	11	2	0.00174064403829417	1149	7161	79001,1728	VKORC1,NQO1
hsa_M00101	Cholesterol biosynthesis, squalene 2,3-epoxide => cholesterol	0.547067671060098	-0.60318277112223	11	2	0.00174064403829417	1149	7161	50814,10682	NSDHL,EBP
hsa04977	Vitamin digestion and absorption	0.55227437592459	-0.593710298362965	24	4	0.00348128807658834	1149	7161	25974,6573,949,4363	MMACHC,SLC19A1,SCARB1,ABCC1
ko04977	Vitamin digestion and absorption	0.55227437592459	-0.593710298362965	24	4	0.00348128807658834	1149	7161	25974,6573,949,4363	MMACHC,SLC19A1,SCARB1,ABCC1
hsa04971	Gastric acid secretion	0.553304212798144	-0.591847315157765	75	12	0.010443864229765	1149	7161	2778,805,476,115,7430,6522,60,3784,2771,5566,818,113	GNAS,CALM2,ATP1A1,ADCY9,EZR,SLC4A2,ACTB,KCNQ1,GNAI2,PRKACA,CAMK2G,ADCY7
ko04971	Gastric acid secretion	0.553304212798144	-0.591847315157765	75	12	0.010443864229765	1149	7161	2778,805,476,115,7430,6522,60,3784,2771,5566,818,113	GNAS,CALM2,ATP1A1,ADCY9,EZR,SLC4A2,ACTB,KCNQ1,GNAI2,PRKACA,CAMK2G,ADCY7
ko04960	Aldosterone-regulated sodium reabsorption	0.557884779117856	-0.583602826958723	37	6	0.00522193211488251	1149	7161	5170,3845,476,5594,5296,5595	PDPK1,KRAS,ATP1A1,MAPK1,PIK3R2,MAPK3
hsa04960	Aldosterone-regulated sodium reabsorption	0.557884779117856	-0.583602826958723	37	6	0.00522193211488251	1149	7161	5170,3845,476,5594,5296,5595	PDPK1,KRAS,ATP1A1,MAPK1,PIK3R2,MAPK3
hsa00770	Pantothenate and CoA biosynthesis	0.569650952260027	-0.562731470181327	18	3	0.00261096605744125	1149	7161	79717,60490,587	PPCS,PPCDC,BCAT2
ko00770	Pantothenate and CoA biosynthesis	0.569650952260027	-0.562731470181327	18	3	0.00261096605744125	1149	7161	79717,60490,587	PPCS,PPCDC,BCAT2
ko00410	beta-Alanine metabolism	0.57043849013705	-0.561349932956268	31	5	0.00435161009573542	1149	7161	23417,6723,221,34,223	MLYCD,SRM,ALDH3B1,ACADM,ALDH9A1
hsa00410	beta-Alanine metabolism	0.57043849013705	-0.561349932956268	31	5	0.00435161009573542	1149	7161	6723,23417,221,34,223	SRM,MLYCD,ALDH3B1,ACADM,ALDH9A1
ko00071	Fatty acid degradation	0.573477323608245	-0.556036883546248	44	7	0.00609225413402959	1149	7161	38,51703,34,51,2181,223,3032	ACAT1,ACSL5,ACADM,ACOX1,ACSL3,ALDH9A1,HADHB
hsa00071	Fatty acid degradation	0.573477323608245	-0.556036883546248	44	7	0.00609225413402959	1149	7161	38,51703,34,51,2181,223,3032	ACAT1,ACSL5,ACADM,ACOX1,ACSL3,ALDH9A1,HADHB
ko04668	TNF signaling pathway	0.575650653630829	-0.55225430639741	108	17	0.0147954743255004	1149	7161	7128,330,208,1432,329,8772,5595,355,8837,23118,5296,4217,9020,1385,1386,5594,7188	TNFAIP3,BIRC3,AKT2,MAPK14,BIRC2,FADD,MAPK3,FAS,CFLAR,TAB2,PIK3R2,MAP3K5,MAP3K14,CREB1,ATF2,MAPK1,TRAF5
hsa04668	TNF signaling pathway	0.575650653630829	-0.55225430639741	108	17	0.0147954743255004	1149	7161	7128,330,208,1432,329,8772,5595,355,8837,23118,5296,4217,9020,1385,1386,5594,7188	TNFAIP3,BIRC3,AKT2,MAPK14,BIRC2,FADD,MAPK3,FAS,CFLAR,TAB2,PIK3R2,MAP3K5,MAP3K14,CREB1,ATF2,MAPK1,TRAF5
M00405	THC complex	0.583024507630095	-0.539526056413815	5	1	0.000870322019147084	1149	7161	9984	THOC1
hsa00400	Phenylalanine, tyrosine and tryptophan biosynthesis	0.583024507630095	-0.539526056413815	5	1	0.000870322019147084	1149	7161	2806	GOT2
hsa_M00405	THC complex	0.583024507630095	-0.539526056413815	5	1	0.000870322019147084	1149	7161	9984	THOC1
M00057	Glycosaminoglycan biosynthesis, linkage tetrasaccharide	0.583024507630095	-0.539526056413815	5	1	0.000870322019147084	1149	7161	126792	B3GALT6
hsa_M00057	Glycosaminoglycan biosynthesis, linkage tetrasaccharide	0.583024507630095	-0.539526056413815	5	1	0.000870322019147084	1149	7161	126792	B3GALT6
ko00400	Phenylalanine, tyrosine and tryptophan biosynthesis	0.583024507630095	-0.539526056413815	5	1	0.000870322019147084	1149	7161	2806	GOT2
hsa_M00002	Glycolysis, core module involving three-carbon compounds	0.596375135949098	-0.516885387186809	12	2	0.00174064403829417	1149	7161	5315,5223	PKM,PGAM1
M00002	Glycolysis, core module involving three-carbon compounds	0.596375135949098	-0.516885387186809	12	2	0.00174064403829417	1149	7161	5315,5223	PKM,PGAM1
hsa05416	Viral myocarditis	0.599299979510836	-0.511993005706491	58	9	0.00783289817232376	1149	7161	27,3106,3133,5879,54205,60,6443,1982,3105	ABL2,HLA-B,HLA-E,RAC1,CYCS,ACTB,SGCB,EIF4G2,HLA-A
ko00051	Fructose and mannose metabolism	0.628899580966786	-0.46378368372836	33	5	0.00435161009573542	1149	7161	5209,231,57103,7264,5214	PFKFB3,AKR1B1,TIGAR,TSTA3,PFKP
hsa00051	Fructose and mannose metabolism	0.628899580966786	-0.46378368372836	33	5	0.00435161009573542	1149	7161	231,5209,57103,7264,5214	AKR1B1,PFKFB3,TIGAR,TSTA3,PFKP
hsa04725	Cholinergic synapse	0.639309277683462	-0.447366939061571	112	17	0.0147954743255004	1149	7161	4893,208,2788,3845,3784,5566,2783,5595,115,5296,596,1385,5594,2771,3265,818,113	NRAS,AKT2,GNG7,KRAS,KCNQ1,PRKACA,GNB2,MAPK3,ADCY9,PIK3R2,BCL2,CREB1,MAPK1,GNAI2,HRAS,CAMK2G,ADCY7
hsa_M00415	Fatty acid biosynthesis, elongation, endoplasmic reticulum	0.641534927531051	-0.443891649750698	13	2	0.00174064403829417	1149	7161	60481,9524	ELOVL5,TECR
hsa00061	Fatty acid biosynthesis	0.641534927531051	-0.443891649750698	13	2	0.00174064403829417	1149	7161	51703,2181	ACSL5,ACSL3
M00415	Fatty acid biosynthesis, elongation, endoplasmic reticulum	0.641534927531051	-0.443891649750698	13	2	0.00174064403829417	1149	7161	60481,9524	ELOVL5,TECR
ko00061	Fatty acid biosynthesis	0.641534927531051	-0.443891649750698	13	2	0.00174064403829417	1149	7161	51703,2181	ACSL5,ACSL3
hsa00100	Steroid biosynthesis	0.644372766013179	-0.439477891121785	20	3	0.00261096605744125	1149	7161	50814,10682,2222	NSDHL,EBP,FDFT1
ko00100	Steroid biosynthesis	0.644372766013179	-0.439477891121785	20	3	0.00261096605744125	1149	7161	50814,2222,10682	NSDHL,FDFT1,EBP
ko00600	Sphingolipid metabolism	0.64662318619006	-0.435991555703862	47	7	0.00609225413402959	1149	7161	427,55627,2581,253782,4758,2629,64781	ASAH1,SMPD4,GALC,CERS6,NEU1,GBA,CERK
hsa00600	Sphingolipid metabolism	0.64662318619006	-0.435991555703862	47	7	0.00609225413402959	1149	7161	427,55627,2581,253782,4758,2629,64781	ASAH1,SMPD4,GALC,CERS6,NEU1,GBA,CERK
hsa00601	Glycosphingolipid biosynthesis - lacto and neolacto series	0.649904539990793	-0.430929788430294	27	4	0.00348128807658834	1149	7161	2683,8702,8703,8704	B4GALT1,B4GALT4,B4GALT3,B4GALT2
M00056	O-glycan biosynthesis, mucin type core	0.649904539990793	-0.430929788430294	27	4	0.00348128807658834	1149	7161	56913,55568,51809,2590	C1GALT1,GALNT10,GALNT7,GALNT2
ko00601	Glycosphingolipid biosynthesis - lacto and neolacto series	0.649904539990793	-0.430929788430294	27	4	0.00348128807658834	1149	7161	2683,8703,8702,8704	B4GALT1,B4GALT3,B4GALT4,B4GALT2
hsa_M00056	O-glycan biosynthesis, mucin type core	0.649904539990793	-0.430929788430294	27	4	0.00348128807658834	1149	7161	56913,55568,51809,2590	C1GALT1,GALNT10,GALNT7,GALNT2
M00013	Malonate semialdehyde pathway, propanoyl-CoA => acetyl-CoA	0.649975994602277	-0.430819848155547	6	1	0.000870322019147084	1149	7161	34	ACADM
hsa_M00141	C1-unit interconversion, eukaryotes	0.649975994602277	-0.430819848155547	6	1	0.000870322019147084	1149	7161	10797	MTHFD2
M00141	C1-unit interconversion, eukaryotes	0.649975994602277	-0.430819848155547	6	1	0.000870322019147084	1149	7161	10797	MTHFD2
M00058	Glycosaminoglycan biosynthesis, chondroitin sulfate backbone	0.649975994602277	-0.430819848155547	6	1	0.000870322019147084	1149	7161	54480	CHPF2
hsa_M00058	Glycosaminoglycan biosynthesis, chondroitin sulfate backbone	0.649975994602277	-0.430819848155547	6	1	0.000870322019147084	1149	7161	54480	CHPF2
hsa_M00013	Malonate semialdehyde pathway, propanoyl-CoA => acetyl-CoA	0.649975994602277	-0.430819848155547	6	1	0.000870322019147084	1149	7161	34	ACADM
ko00010	Glycolysis / Gluconeogenesis	0.650306861985959	-0.430310932131396	67	10	0.00870322019147084	1149	7161	221,3939,2821,83440,9562,5315,5223,5214,223,3945	ALDH3B1,LDHA,GPI,ADPGK,MINPP1,PKM,PGAM1,PFKP,ALDH9A1,LDHB
hsa00010	Glycolysis / Gluconeogenesis	0.650306861985959	-0.430310932131396	67	10	0.00870322019147084	1149	7161	221,3939,2821,83440,9562,5315,5223,5214,3945,223	ALDH3B1,LDHA,GPI,ADPGK,MINPP1,PKM,PGAM1,PFKP,LDHB,ALDH9A1
hsa00480	Glutathione metabolism	0.654649221099748	-0.423655727105542	54	8	0.00696257615317668	1149	7161	6723,373156,2730,51056,6240,6241,4953,2879	SRM,GSTK1,GCLM,LAP3,RRM1,RRM2,ODC1,GPX4
ko00480	Glutathione metabolism	0.654649221099748	-0.423655727105542	54	8	0.00696257615317668	1149	7161	6723,373156,2730,51056,6240,6241,4953,2879	SRM,GSTK1,GCLM,LAP3,RRM1,RRM2,ODC1,GPX4
hsa04015	Rap1 signaling pathway	0.656077952027239	-0.421475667787875	210	32	0.0278503046127067	1149	7161	5894,5879,7410,1432,51735,1399,805,2261,23683,5906,7408,998,5899,5296,115,2149,2771,113,4893,387,208,3845,5605,889,5595,4301,2778,3688,60,5594,3265,56288	RAF1,RAC1,VAV2,MAPK14,RAPGEF6,CRKL,CALM2,FGFR3,PRKD3,RAP1A,VASP,CDC42,RALB,PIK3R2,ADCY9,F2R,GNAI2,ADCY7,NRAS,RHOA,AKT2,KRAS,MAP2K2,KRIT1,MAPK3,AFDN,GNAS,ITGB1,ACTB,MAPK1,HRAS,PARD3
ko04015	Rap1 signaling pathway	0.656077952027239	-0.421475667787875	210	32	0.0278503046127067	1149	7161	5894,5879,7410,1432,51735,1399,805,2261,23683,5906,7408,998,5899,5296,115,2149,2771,113,4893,387,208,3845,5605,889,5595,4301,2778,3688,60,5594,3265,56288	RAF1,RAC1,VAV2,MAPK14,RAPGEF6,CRKL,CALM2,FGFR3,PRKD3,RAP1A,VASP,CDC42,RALB,PIK3R2,ADCY9,F2R,GNAI2,ADCY7,NRAS,RHOA,AKT2,KRAS,MAP2K2,KRIT1,MAPK3,AFDN,GNAS,ITGB1,ACTB,MAPK1,HRAS,PARD3
ko04260	Cardiac muscle contraction	0.658198053536541	-0.418249399729562	74	11	0.00957354221061793	1149	7161	782,1329,476,488,29796,9167,1351,9377,7388,1327,1537	CACNB1,COX5B,ATP1A1,ATP2A2,UQCR10,COX7A2L,COX8A,COX5A,UQCRH,COX4I1,CYC1
hsa04260	Cardiac muscle contraction	0.658198053536541	-0.418249399729562	74	11	0.00957354221061793	1149	7161	782,1329,476,488,29796,9167,1351,9377,7388,1327,1537	CACNB1,COX5B,ATP1A1,ATP2A2,UQCR10,COX7A2L,COX8A,COX5A,UQCRH,COX4I1,CYC1
hsa04931	Insulin resistance	0.662242481538082	-0.412123503800282	107	16	0.0139251523063534	1149	7161	5170,5792,79660,5564,6945,5728,6195,208,5296,5562,6513,5781,8473,10999,1385,6774	PDPK1,PTPRF,PPP1R3B,PRKAB1,MLX,PTEN,RPS6KA1,AKT2,PIK3R2,PRKAA1,SLC2A1,PTPN11,OGT,SLC27A4,CREB1,STAT3
hsa04975	Fat digestion and absorption	0.662786780099868	-0.41130193916294	41	6	0.00522193211488251	1149	7161	10999,949,10555,2806,19,10554	SLC27A4,SCARB1,AGPAT2,GOT2,ABCA1,AGPAT1
ko04975	Fat digestion and absorption	0.662786780099868	-0.41130193916294	41	6	0.00522193211488251	1149	7161	10999,949,10555,2806,19,10554	SLC27A4,SCARB1,AGPAT2,GOT2,ABCA1,AGPAT1
ko04670	Leukocyte transendothelial migration	0.669292760363229	-0.401533705663119	114	17	0.0147954743255004	1149	7161	387,5879,7410,7430,1432,7409,4301,5906,7408,998,5296,3688,5781,60,6093,2771,103910	RHOA,RAC1,VAV2,EZR,MAPK14,VAV1,AFDN,RAP1A,VASP,CDC42,PIK3R2,ITGB1,PTPN11,ACTB,ROCK1,GNAI2,MYL12B
hsa04670	Leukocyte transendothelial migration	0.669292760363229	-0.401533705663119	114	17	0.0147954743255004	1149	7161	387,5879,7410,7430,1432,7409,4301,5906,7408,998,5296,3688,5781,60,6093,2771,103910	RHOA,RAC1,VAV2,EZR,MAPK14,VAV1,AFDN,RAP1A,VASP,CDC42,PIK3R2,ITGB1,PTPN11,ACTB,ROCK1,GNAI2,MYL12B
hsa04270	Vascular smooth muscle contraction	0.676023379642291	-0.391527618267568	121	18	0.0156657963446475	1149	7161	387,4659,5894,23365,5566,140465,5605,5595,805,2778,2768,2983,115,9138,54776,6093,5594,113	RHOA,PPP1R12A,RAF1,ARHGEF12,PRKACA,MYL6B,MAP2K2,MAPK3,CALM2,GNAS,GNA12,GUCY1B1,ADCY9,ARHGEF1,PPP1R12C,ROCK1,MAPK1,ADCY7
ko04270	Vascular smooth muscle contraction	0.676023379642291	-0.391527618267568	121	18	0.0156657963446475	1149	7161	387,4659,5894,23365,5566,140465,5605,5595,805,2778,2768,2983,115,9138,54776,6093,5594,113	RHOA,PPP1R12A,RAF1,ARHGEF12,PRKACA,MYL6B,MAP2K2,MAPK3,CALM2,GNAS,GNA12,GUCY1B1,ADCY9,ARHGEF1,PPP1R12C,ROCK1,MAPK1,ADCY7
hsa_M00688	MAPK (JNK) signaling	0.678113786763021	-0.388440178039029	21	3	0.00261096605744125	1149	7161	4216,4217,57551	MAP3K4,MAP3K5,TAOK1
hsa_M00049	Adenine ribonucleotide biosynthesis, IMP => ADP,ATP	0.678113786763021	-0.388440178039029	21	3	0.00261096605744125	1149	7161	159,158,5315	ADSS,ADSL,PKM
M00688	MAPK (JNK) signaling	0.678113786763021	-0.388440178039029	21	3	0.00261096605744125	1149	7161	4216,4217,57551	MAP3K4,MAP3K5,TAOK1
M00049	Adenine ribonucleotide biosynthesis, IMP => ADP,ATP	0.678113786763021	-0.388440178039029	21	3	0.00261096605744125	1149	7161	159,158,5315	ADSS,ADSL,PKM
hsa00250	Alanine, aspartate and glutamate metabolism	0.6822634280371	-0.382339437598223	35	5	0.00435161009573542	1149	7161	158,159,56954,2746,2806	ADSL,ADSS,NIT2,GLUD1,GOT2
ko00250	Alanine, aspartate and glutamate metabolism	0.6822634280371	-0.382339437598223	35	5	0.00435161009573542	1149	7161	158,159,56954,2746,2806	ADSL,ADSS,NIT2,GLUD1,GOT2
hsa05142	Chagas disease (American trypanosomiasis)	0.685837132008255	-0.377115096341692	102	15	0.0130548302872063	1149	7161	2778,7040,5515,4087,208,5296,148022,1432,5594,2771,55844,8772,5595,355,8837	GNAS,TGFB1,PPP2CA,SMAD2,AKT2,PIK3R2,TICAM1,MAPK14,MAPK1,GNAI2,PPP2R2D,FADD,MAPK3,FAS,CFLAR
ko05142	Chagas disease (American trypanosomiasis)	0.685837132008255	-0.377115096341692	102	15	0.0130548302872063	1149	7161	2778,7040,5515,4087,208,5296,148022,1432,5594,2771,55844,8772,5595,355,8837	GNAS,TGFB1,PPP2CA,SMAD2,AKT2,PIK3R2,TICAM1,MAPK14,MAPK1,GNAI2,PPP2R2D,FADD,MAPK3,FAS,CFLAR
ko04920	Adipocytokine signaling pathway	0.687869413666548	-0.374156264781405	69	10	0.00870322019147084	1149	7161	51703,5564,208,6513,2181,5562,5781,6794,6774,6257	ACSL5,PRKAB1,AKT2,SLC2A1,ACSL3,PRKAA1,PTPN11,STK11,STAT3,RXRB
hsa04920	Adipocytokine signaling pathway	0.687869413666548	-0.374156264781405	69	10	0.00870322019147084	1149	7161	51703,5564,208,6513,2181,5562,5781,6794,6774,6257	ACSL5,PRKAB1,AKT2,SLC2A1,ACSL3,PRKAA1,PTPN11,STK11,STAT3,RXRB
ko05414	Dilated cardiomyopathy	0.688981951903326	-0.372540202936634	89	13	0.0113141862489121	1149	7161	7040,2778,782,3696,488,115,3688,60,6443,3693,5566,4000,113	TGFB1,GNAS,CACNB1,ITGB8,ATP2A2,ADCY9,ITGB1,ACTB,SGCB,ITGB5,PRKACA,LMNA,ADCY7
hsa05414	Dilated cardiomyopathy	0.688981951903326	-0.372540202936634	89	13	0.0113141862489121	1149	7161	7040,2778,782,3696,488,115,3688,60,6443,3693,5566,4000,113	TGFB1,GNAS,CACNB1,ITGB8,ATP2A2,ADCY9,ITGB1,ACTB,SGCB,ITGB5,PRKACA,LMNA,ADCY7
M00549	Nucleotide sugar biosynthesis, glucose => UDP-glucose	0.706185300288702	-0.347877610928645	7	1	0.000870322019147084	1149	7161	7360	UGP2
M00397	Lsm 1-7 complex	0.706185300288702	-0.347877610928645	7	1	0.000870322019147084	1149	7161	11157	LSM6
hsa_M00397	Lsm 1-7 complex	0.706185300288702	-0.347877610928645	7	1	0.000870322019147084	1149	7161	11157	LSM6
hsa_M00549	Nucleotide sugar biosynthesis, glucose => UDP-glucose	0.706185300288702	-0.347877610928645	7	1	0.000870322019147084	1149	7161	7360	UGP2
hsa05340	Primary immunodeficiency	0.706922366816764	-0.34683442559739	36	5	0.00435161009573542	1149	7161	84876,6891,64421,8625,6890	ORAI1,TAP2,DCLRE1C,RFXANK,TAP1
ko05340	Primary immunodeficiency	0.706922366816764	-0.34683442559739	36	5	0.00435161009573542	1149	7161	84876,6891,64421,8625,6890	ORAI1,TAP2,DCLRE1C,RFXANK,TAP1
ko04728	Dopaminergic synapse	0.709020839017274	-0.343870360756035	130	19	0.0165361183637946	1149	7161	5530,208,2788,5532,1432,5566,2783,2778,5515,3799,805,5525,406,1385,1386,409,2771,55844,818	PPP3CA,AKT2,GNG7,PPP3CB,MAPK14,PRKACA,GNB2,GNAS,PPP2CA,KIF5B,CALM2,PPP2R5A,ARNTL,CREB1,ATF2,ARRB2,GNAI2,PPP2R2D,CAMK2G
hsa04728	Dopaminergic synapse	0.709020839017274	-0.343870360756035	130	19	0.0165361183637946	1149	7161	5530,208,2788,5532,1432,5566,2783,2778,5515,3799,805,5525,406,1385,1386,409,2771,55844,818	PPP3CA,AKT2,GNG7,PPP3CB,MAPK14,PRKACA,GNB2,GNAS,PPP2CA,KIF5B,CALM2,PPP2R5A,ARNTL,CREB1,ATF2,ARRB2,GNAI2,PPP2R2D,CAMK2G
hsa04612	Antigen processing and presentation	0.710565638545462	-0.341693952115374	77	11	0.00957354221061793	1149	7161	1514,3106,1520,3308,3133,8625,6890,6891,1385,3105,3304	CTSL,HLA-B,CTSS,HSPA4,HLA-E,RFXANK,TAP1,TAP2,CREB1,HLA-A,HSPA1B
ko04612	Antigen processing and presentation	0.710565638545462	-0.341693952115374	77	11	0.00957354221061793	1149	7161	1514,3106,1520,3308,3133,8625,6890,6891,1385,3105,3304	CTSL,HLA-B,CTSS,HSPA4,HLA-E,RFXANK,TAP1,TAP2,CREB1,HLA-A,HSPA1B
ko00790	Folate biosynthesis	0.719741062151576	-0.328863767557124	15	2	0.00174064403829417	1149	7161	200895,6697	DHFR2,SPR
hsa00790	Folate biosynthesis	0.719741062151576	-0.328863767557124	15	2	0.00174064403829417	1149	7161	200895,6697	DHFR2,SPR
ko04024	cAMP signaling pathway	0.735463381710764	-0.307254527113075	198	29	0.0252393385552654	1149	7161	387,4659,208,5894,5879,7410,154,5140,5566,5605,5595,2778,7409,4301,805,5906,476,488,51,5296,115,84876,6093,1385,2149,2771,5594,818,113	RHOA,PPP1R12A,AKT2,RAF1,RAC1,VAV2,ADRB2,PDE3B,PRKACA,MAP2K2,MAPK3,GNAS,VAV1,AFDN,CALM2,RAP1A,ATP1A1,ATP2A2,ACOX1,PIK3R2,ADCY9,ORAI1,ROCK1,CREB1,F2R,GNAI2,MAPK1,CAMK2G,ADCY7
hsa04024	cAMP signaling pathway	0.735463381710764	-0.307254527113075	198	29	0.0252393385552654	1149	7161	387,4659,208,5894,5879,7410,154,5140,5566,5605,5595,2778,7409,4301,805,5906,476,488,51,5296,115,84876,6093,1385,2149,2771,5594,818,113	RHOA,PPP1R12A,AKT2,RAF1,RAC1,VAV2,ADRB2,PDE3B,PRKACA,MAP2K2,MAPK3,GNAS,VAV1,AFDN,CALM2,RAP1A,ATP1A1,ATP2A2,ACOX1,PIK3R2,ADCY9,ORAI1,ROCK1,CREB1,F2R,GNAI2,MAPK1,CAMK2G,ADCY7
hsa04964	Proximal tubule bicarbonate reclamation	0.738330453430995	-0.303363785723546	23	3	0.00261096605744125	1149	7161	4190,2746,476	MDH1,GLUD1,ATP1A1
ko01040	Biosynthesis of unsaturated fatty acids	0.738330453430995	-0.303363785723546	23	3	0.00261096605744125	1149	7161	60481,9524,51	ELOVL5,TECR,ACOX1
ko04964	Proximal tubule bicarbonate reclamation	0.738330453430995	-0.303363785723546	23	3	0.00261096605744125	1149	7161	4190,2746,476	MDH1,GLUD1,ATP1A1
hsa01040	Biosynthesis of unsaturated fatty acids	0.738330453430995	-0.303363785723546	23	3	0.00261096605744125	1149	7161	60481,9524,51	ELOVL5,TECR,ACOX1
hsa05202	Transcriptional misregulation in cancer	0.742683274857628	-0.297485603938897	179	26	0.0226283724978242	1149	7161	2130,4149,55204,330,2138,6929,8861,598,4221,84444,6257,1031,3087,4193,100532731,7030,2530,2120,5371,1027,4299,1655,2521,3020,4086,3066	EWSR1,MAX,GOLPH3L,BIRC3,EYA1,TCF3,LDB1,BCL2L1,MEN1,DOT1L,RXRB,CDKN2C,HHEX,MDM2,COMMD3-BMI1,TFE3,FUT8,ETV6,PML,CDKN1B,AFF1,DDX5,FUS,H3F3A,SMAD1,HDAC2
ko05202	Transcriptional misregulation in cancer	0.742683274857628	-0.297485603938897	179	26	0.0226283724978242	1149	7161	2130,4149,55204,330,2138,6929,8861,598,4221,84444,6257,1031,3087,4193,100532731,7030,2530,2120,5371,1027,4299,1655,2521,3020,4086,3066	EWSR1,MAX,GOLPH3L,BIRC3,EYA1,TCF3,LDB1,BCL2L1,MEN1,DOT1L,RXRB,CDKN2C,HHEX,MDM2,COMMD3-BMI1,TFE3,FUT8,ETV6,PML,CDKN1B,AFF1,DDX5,FUS,H3F3A,SMAD1,HDAC2
ko00561	Glycerolipid metabolism	0.751532418015605	-0.285640932974198	59	8	0.00696257615317668	1149	7161	10555,9663,10554,231,154141,56894,253558,223	AGPAT2,LPIN2,AGPAT1,AKR1B1,MBOAT1,AGPAT3,LCLAT1,ALDH9A1
hsa00561	Glycerolipid metabolism	0.751532418015605	-0.285640932974198	59	8	0.00696257615317668	1149	7161	10555,9663,10554,231,154141,56894,253558,223	AGPAT2,LPIN2,AGPAT1,AKR1B1,MBOAT1,AGPAT3,LCLAT1,ALDH9A1
M00099	Sphingosine biosynthesis	0.753140898836058	-0.283502952038229	16	2	0.00174064403829417	1149	7161	427,253782	ASAH1,CERS6
hsa_M00099	Sphingosine biosynthesis	0.753140898836058	-0.283502952038229	16	2	0.00174064403829417	1149	7161	427,253782	ASAH1,CERS6
hsa04122	Sulfur relay system	0.753374717401543	-0.283192542288947	8	1	0.000870322019147084	1149	7161	348180	CTU2
hsa_M00406	TREX complex	0.753374717401543	-0.283192542288947	8	1	0.000870322019147084	1149	7161	9984	THOC1
M00406	TREX complex	0.753374717401543	-0.283192542288947	8	1	0.000870322019147084	1149	7161	9984	THOC1
M00428	eIF4F complex	0.753374717401543	-0.283192542288947	8	1	0.000870322019147084	1149	7161	1982	EIF4G2
hsa_M00428	eIF4F complex	0.753374717401543	-0.283192542288947	8	1	0.000870322019147084	1149	7161	1982	EIF4G2
ko04122	Sulfur relay system	0.753374717401543	-0.283192542288947	8	1	0.000870322019147084	1149	7161	348180	CTU2
ko04972	Pancreatic secretion	0.776118870825498	-0.253449586476921	95	13	0.0113141862489121	1149	7161	2778,4218,5906,476,387,488,5879,115,6522,3784,6558,8766,113	GNAS,RAB8A,RAP1A,ATP1A1,RHOA,ATP2A2,RAC1,ADCY9,SLC4A2,KCNQ1,SLC12A2,RAB11A,ADCY7
hsa04972	Pancreatic secretion	0.776118870825498	-0.253449586476921	95	13	0.0113141862489121	1149	7161	2778,4218,5906,476,387,488,5879,115,6522,3784,6558,8766,113	GNAS,RAB8A,RAP1A,ATP1A1,RHOA,ATP2A2,RAC1,ADCY9,SLC4A2,KCNQ1,SLC12A2,RAB11A,ADCY7
ko04630	Jak-STAT signaling pathway	0.779120639680476	-0.249589380300067	156	22	0.0191470844212359	1149	7161	5894,208,4170,3594,598,50615,8027,30837,5771,3716,6778,3572,5296,122809,9063,9306,6772,5781,596,6774,3265,9655	RAF1,AKT2,MCL1,IL12RB1,BCL2L1,IL21R,STAM,SOCS7,PTPN2,JAK1,STAT6,IL6ST,PIK3R2,SOCS4,PIAS2,SOCS6,STAT1,PTPN11,BCL2,STAT3,HRAS,SOCS5
hsa04630	Jak-STAT signaling pathway	0.779120639680476	-0.249589380300067	156	22	0.0191470844212359	1149	7161	5894,208,4170,3594,598,50615,8027,30837,5771,3716,6778,3572,5296,122809,9063,9306,6772,5781,596,6774,3265,9655	RAF1,AKT2,MCL1,IL12RB1,BCL2L1,IL21R,STAM,SOCS7,PTPN2,JAK1,STAT6,IL6ST,PIK3R2,SOCS4,PIAS2,SOCS6,STAT1,PTPN11,BCL2,STAT3,HRAS,SOCS5
hsa00450	Selenocompound metabolism	0.783048204905945	-0.244561020510934	17	2	0.00174064403829417	1149	7161	22928,4548	SEPHS2,MTR
ko00450	Selenocompound metabolism	0.783048204905945	-0.244561020510934	17	2	0.00174064403829417	1149	7161	22928,4548	SEPHS2,MTR
hsa05031	Amphetamine addiction	0.78432216575715	-0.242935417327927	68	9	0.00783289817232376	1149	7161	2778,805,5530,5534,5532,1385,5566,1386,818	GNAS,CALM2,PPP3CA,PPP3R1,PPP3CB,CREB1,PRKACA,ATF2,CAMK2G
ko05031	Amphetamine addiction	0.78432216575715	-0.242935417327927	68	9	0.00783289817232376	1149	7161	2778,805,5530,5534,5532,1385,5566,1386,818	GNAS,CALM2,PPP3CA,PPP3R1,PPP3CB,CREB1,PRKACA,ATF2,CAMK2G
hsa04925	Aldosterone synthesis and secretion	0.785863650282594	-0.240971974524006	82	11	0.00957354221061793	1149	7161	2778,805,23683,115,84876,949,1385,5566,1386,818,113	GNAS,CALM2,PRKD3,ADCY9,ORAI1,SCARB1,CREB1,PRKACA,ATF2,CAMK2G,ADCY7
ko04925	Aldosterone synthesis and secretion	0.785863650282594	-0.240971974524006	82	11	0.00957354221061793	1149	7161	2778,805,23683,115,84876,949,1385,5566,1386,818,113	GNAS,CALM2,PRKD3,ADCY9,ORAI1,SCARB1,CREB1,PRKACA,ATF2,CAMK2G,ADCY7
hsa05323	Rheumatoid arthritis	0.787216167901994	-0.239252394961618	89	12	0.010443864229765	1149	7161	1514,7040,533,51382,23545,535,527,528,526,8992,9114,9550	CTSL,TGFB1,ATP6V0B,ATP6V1D,ATP6V0A2,ATP6V0A1,ATP6V0C,ATP6V1C1,ATP6V1B2,ATP6V0E1,ATP6V0D1,ATP6V1G1
ko05323	Rheumatoid arthritis	0.787216167901994	-0.239252394961618	89	12	0.010443864229765	1149	7161	1514,7040,533,51382,23545,535,527,528,526,8992,9114,9550	CTSL,TGFB1,ATP6V0B,ATP6V1D,ATP6V0A2,ATP6V0A1,ATP6V0C,ATP6V1C1,ATP6V1B2,ATP6V0E1,ATP6V0D1,ATP6V1G1
ko04713	Circadian entrainment	0.788829333617939	-0.237205288735638	96	13	0.0113141862489121	1149	7161	2778,805,2983,2788,115,1385,5594,5566,2771,2783,818,5595,113	GNAS,CALM2,GUCY1B1,GNG7,ADCY9,CREB1,MAPK1,PRKACA,GNAI2,GNB2,CAMK2G,MAPK3,ADCY7
hsa04713	Circadian entrainment	0.788829333617939	-0.237205288735638	96	13	0.0113141862489121	1149	7161	2778,805,2983,2788,115,1385,5594,5566,2771,2783,818,5595,113	GNAS,CALM2,GUCY1B1,GNG7,ADCY9,CREB1,MAPK1,PRKACA,GNAI2,GNB2,CAMK2G,MAPK3,ADCY7
M00694	cGMP signaling	0.792990605798414	-0.231943903825512	9	1	0.000870322019147084	1149	7161	2983	GUCY1B1
hsa_M00694	cGMP signaling	0.792990605798414	-0.231943903825512	9	1	0.000870322019147084	1149	7161	2983	GUCY1B1
ko05133	Pertussis	0.798672420406593	-0.224804404258979	76	10	0.00870322019147084	1149	7161	805,387,3688,148022,3661,5594,2771,1432,1072,5595	CALM2,RHOA,ITGB1,TICAM1,IRF3,MAPK1,GNAI2,MAPK14,CFL1,MAPK3
hsa05133	Pertussis	0.798672420406593	-0.224804404258979	76	10	0.00870322019147084	1149	7161	805,387,3688,148022,3661,5594,2771,1432,1072,5595	CALM2,RHOA,ITGB1,TICAM1,IRF3,MAPK1,GNAI2,MAPK14,CFL1,MAPK3
ko05410	Hypertrophic cardiomyopathy (HCM)	0.799085425141023	-0.224287423860755	83	11	0.00957354221061793	1149	7161	7040,782,5564,3696,488,5562,3688,60,3693,6443,4000	TGFB1,CACNB1,PRKAB1,ITGB8,ATP2A2,PRKAA1,ITGB1,ACTB,ITGB5,SGCB,LMNA
hsa05410	Hypertrophic cardiomyopathy (HCM)	0.799085425141023	-0.224287423860755	83	11	0.00957354221061793	1149	7161	7040,782,5564,3696,488,5562,3688,60,3693,6443,4000	TGFB1,CACNB1,PRKAB1,ITGB8,ATP2A2,PRKAA1,ITGB1,ACTB,ITGB5,SGCB,LMNA
ko04620	Toll-like receptor signaling pathway	0.802376966726577	-0.220176748221774	104	14	0.0121845082680592	1149	7161	23118,208,5296,5879,6772,148022,3661,5594,54472,1432,5605,3663,8772,5595	TAB2,AKT2,PIK3R2,RAC1,STAT1,TICAM1,IRF3,MAPK1,TOLLIP,MAPK14,MAP2K2,IRF5,FADD,MAPK3
hsa04620	Toll-like receptor signaling pathway	0.802376966726577	-0.220176748221774	104	14	0.0121845082680592	1149	7161	23118,208,5296,5879,6772,148022,3661,5594,54472,1432,5605,3663,8772,5595	TAB2,AKT2,PIK3R2,RAC1,STAT1,TICAM1,IRF3,MAPK1,TOLLIP,MAPK14,MAP2K2,IRF5,FADD,MAPK3
hsa04014	Ras signaling pathway	0.808591862061495	-0.212460986058741	226	32	0.0278503046127067	1149	7161	8036,387,4893,4763,208,5894,5879,2788,8315,3845,598,2002,5869,2113,5566,2783,5605,5595,27,4301,805,2261,5906,6464,2114,998,5899,5296,5781,23179,5594,3265	SHOC2,RHOA,NRAS,NF1,AKT2,RAF1,RAC1,GNG7,BRAP,KRAS,BCL2L1,ELK1,RAB5B,ETS1,PRKACA,GNB2,MAP2K2,MAPK3,ABL2,AFDN,CALM2,FGFR3,RAP1A,SHC1,ETS2,CDC42,RALB,PIK3R2,PTPN11,RGL1,MAPK1,HRAS
hsa04623	Cytosolic DNA-sensing pathway	0.81399738184588	-0.205798129390323	63	8	0.00696257615317668	1149	7161	23586,5441,115004,5440,84265,57506,3661,51728	DDX58,POLR2L,CGAS,POLR2K,POLR3GL,MAVS,IRF3,POLR3K
ko04623	Cytosolic DNA-sensing pathway	0.81399738184588	-0.205798129390323	63	8	0.00696257615317668	1149	7161	23586,5441,115004,5440,84265,57506,3661,51728	DDX58,POLR2L,CGAS,POLR2K,POLR3GL,MAVS,IRF3,POLR3K
ko05162	Measles	0.819135106163136	-0.199506243944109	133	18	0.0156657963446475	1149	7161	23586,7128,208,1457,27102,3661,440275,8667,3304,355,3716,23118,5296,6772,1027,57506,6774,1017	DDX58,TNFAIP3,AKT2,CSNK2A1,EIF2AK1,IRF3,EIF2AK4,EIF3H,HSPA1B,FAS,JAK1,TAB2,PIK3R2,STAT1,CDKN1B,MAVS,STAT3,CDK2
hsa05162	Measles	0.819135106163136	-0.199506243944109	133	18	0.0156657963446475	1149	7161	23586,7128,208,1457,27102,3661,440275,8667,3304,355,3716,23118,5296,6772,1027,57506,6774,1017	DDX58,TNFAIP3,AKT2,CSNK2A1,EIF2AK1,IRF3,EIF2AK4,EIF3H,HSPA1B,FAS,JAK1,TAB2,PIK3R2,STAT1,CDKN1B,MAVS,STAT3,CDK2
hsa05030	Cocaine addiction	0.820480347222077	-0.197865320936196	49	6	0.00522193211488251	1149	7161	2778,1020,1385,2771,1386,5566	GNAS,CDK5,CREB1,GNAI2,ATF2,PRKACA
ko05030	Cocaine addiction	0.820480347222077	-0.197865320936196	49	6	0.00522193211488251	1149	7161	2778,1020,1385,2771,1386,5566	GNAS,CDK5,CREB1,GNAI2,ATF2,PRKACA
hsa04390	Hippo signaling pathway	0.824279012230542	-0.193246199311203	154	21	0.0182767624020888	1149	7161	7040,329,8323,5515,4087,332,8312,81029,8313,60,7534,1855,7159,4086,55233,7533,55844,4089,1453,1856,56288	TGFB1,BIRC2,FZD6,PPP2CA,SMAD2,BIRC5,AXIN1,WNT5B,AXIN2,ACTB,YWHAZ,DVL1,TP53BP2,SMAD1,MOB1A,YWHAH,PPP2R2D,SMAD4,CSNK1D,DVL2,PARD3
ko04390	Hippo signaling pathway	0.824279012230542	-0.193246199311203	154	21	0.0182767624020888	1149	7161	7040,329,8323,5515,4087,332,8312,81029,8313,60,7534,1855,7159,4086,55233,7533,55844,4089,1453,1856,56288	TGFB1,BIRC2,FZD6,PPP2CA,SMAD2,BIRC5,AXIN1,WNT5B,AXIN2,ACTB,YWHAZ,DVL1,TP53BP2,SMAD1,MOB1A,YWHAH,PPP2R2D,SMAD4,CSNK1D,DVL2,PARD3
M00296	BER complex	0.826247568038422	-0.190860831193134	10	1	0.000870322019147084	1149	7161	143	PARP4
M00059	Glycosaminoglycan biosynthesis, heparan sulfate backbone	0.826247568038422	-0.190860831193134	10	1	0.000870322019147084	1149	7161	2132	EXT2
hsa_M00296	BER complex	0.826247568038422	-0.190860831193134	10	1	0.000870322019147084	1149	7161	143	PARP4
hsa_M00059	Glycosaminoglycan biosynthesis, heparan sulfate backbone	0.826247568038422	-0.190860831193134	10	1	0.000870322019147084	1149	7161	2132	EXT2
hsa05140	Leishmaniasis	0.837846964534496	-0.176919815064333	72	9	0.00783289817232376	1149	7161	7040,3716,23118,6772,3688,2002,5594,1432,5595	TGFB1,JAK1,TAB2,STAT1,ITGB1,ELK1,MAPK1,MAPK14,MAPK3
ko05140	Leishmaniasis	0.837846964534496	-0.176919815064333	72	9	0.00783289817232376	1149	7161	7040,3716,23118,6772,3688,2002,5594,1432,5595	TGFB1,JAK1,TAB2,STAT1,ITGB1,ELK1,MAPK1,MAPK14,MAPK3
hsa04380	Osteoclast differentiation	0.845734032178581	-0.16755035157217	129	17	0.0147954743255004	1149	7161	7040,5530,1540,3716,23118,208,5879,5296,6772,5534,4773,5532,1385,9020,1432,5594,5595	TGFB1,PPP3CA,CYLD,JAK1,TAB2,AKT2,RAC1,PIK3R2,STAT1,PPP3R1,NFATC2,PPP3CB,CREB1,MAP3K14,MAPK14,MAPK1,MAPK3
ko04380	Osteoclast differentiation	0.845734032178581	-0.16755035157217	129	17	0.0147954743255004	1149	7161	7040,5530,1540,3716,23118,208,5879,5296,6772,5534,4773,5532,1385,9020,1432,5594,5595	TGFB1,PPP3CA,CYLD,JAK1,TAB2,AKT2,RAC1,PIK3R2,STAT1,PPP3R1,NFATC2,PPP3CB,CREB1,MAP3K14,MAPK14,MAPK1,MAPK3
hsa00650	Butanoate metabolism	0.84995763188417	-0.162568775582223	28	3	0.00261096605744125	1149	7161	38,65985,622	ACAT1,AACS,BDH1
ko00650	Butanoate metabolism	0.84995763188417	-0.162568775582223	28	3	0.00261096605744125	1149	7161	38,65985,622	ACAT1,AACS,BDH1
hsa00430	Taurine and hypotaurine metabolism	0.854165557743279	-0.157630242456197	11	1	0.000870322019147084	1149	7161	84890	ADO
hsa_M00032	Lysine degradation, lysine => saccharopine => acetoacetyl-CoA	0.854165557743279	-0.157630242456197	11	1	0.000870322019147084	1149	7161	4967	OGDH
ko00430	Taurine and hypotaurine metabolism	0.854165557743279	-0.157630242456197	11	1	0.000870322019147084	1149	7161	84890	ADO
M00032	Lysine degradation, lysine => saccharopine => acetoacetyl-CoA	0.854165557743279	-0.157630242456197	11	1	0.000870322019147084	1149	7161	4967	OGDH
ko00532	Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate	0.854437830663668	-0.157311534294267	20	2	0.00174064403829417	1149	7161	126792,54480	B3GALT6,CHPF2
hsa_M00679	BMP signaling	0.854437830663668	-0.157311534294267	20	2	0.00174064403829417	1149	7161	4086,4089	SMAD1,SMAD4
hsa00532	Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate	0.854437830663668	-0.157311534294267	20	2	0.00174064403829417	1149	7161	126792,54480	B3GALT6,CHPF2
M00679	BMP signaling	0.854437830663668	-0.157311534294267	20	2	0.00174064403829417	1149	7161	4086,4089	SMAD1,SMAD4
ko00760	Nicotinate and nicotinamide metabolism	0.866504612566011	-0.143287846625399	29	3	0.00261096605744125	1149	7161	133686,55191,115024	NADK2,NADSYN1,NT5C3B
hsa00760	Nicotinate and nicotinamide metabolism	0.866504612566011	-0.143287846625399	29	3	0.00261096605744125	1149	7161	133686,55191,115024	NADK2,NADSYN1,NT5C3B
hsa05330	Allograft rejection	0.866573360532882	-0.143208510360125	37	4	0.00348128807658834	1149	7161	3106,3133,3105,355	HLA-B,HLA-E,HLA-A,FAS
ko05330	Allograft rejection	0.866573360532882	-0.143208510360125	37	4	0.00348128807658834	1149	7161	3106,3133,3105,355	HLA-B,HLA-E,HLA-A,FAS
ko00220	Arginine biosynthesis	0.872998256340875	-0.135821720463114	21	2	0.00174064403829417	1149	7161	2746,2806	GLUD1,GOT2
hsa00220	Arginine biosynthesis	0.872998256340875	-0.135821720463114	21	2	0.00174064403829417	1149	7161	2746,2806	GLUD1,GOT2
M00094	Ceramide biosynthesis	0.877601050640275	-0.130563172847408	12	1	0.000870322019147084	1149	7161	253782	CERS6
hsa_M00290	Holo-TFIIH complex	0.877601050640275	-0.130563172847408	12	1	0.000870322019147084	1149	7161	2966	GTF2H2
hsa_M00052	Pyrimidine ribonucleotide biosynthesis, UMP => UDP/UTP,CDP/CTP	0.877601050640275	-0.130563172847408	12	1	0.000870322019147084	1149	7161	1503	CTPS1
M00052	Pyrimidine ribonucleotide biosynthesis, UMP => UDP/UTP,CDP/CTP	0.877601050640275	-0.130563172847408	12	1	0.000870322019147084	1149	7161	1503	CTPS1
M00290	Holo-TFIIH complex	0.877601050640275	-0.130563172847408	12	1	0.000870322019147084	1149	7161	2966	GTF2H2
hsa_M00094	Ceramide biosynthesis	0.877601050640275	-0.130563172847408	12	1	0.000870322019147084	1149	7161	253782	CERS6
hsa_M00677	Wnt signaling	0.880037699508842	-0.127790532076549	38	4	0.00348128807658834	1149	7161	1855,81029,1856,8323	DVL1,WNT5B,DVL2,FZD6
M00677	Wnt signaling	0.880037699508842	-0.127790532076549	38	4	0.00348128807658834	1149	7161	1855,81029,1856,8323	DVL1,WNT5B,DVL2,FZD6
ko04930	Type II diabetes mellitus	0.881722423635382	-0.125877984939235	46	5	0.00435161009573542	1149	7161	5315,5594,5296,5595,122809	PKM,MAPK1,PIK3R2,MAPK3,SOCS4
hsa04930	Type II diabetes mellitus	0.881722423635382	-0.125877984939235	46	5	0.00435161009573542	1149	7161	5315,5594,5296,5595,122809	PKM,MAPK1,PIK3R2,MAPK3,SOCS4
hsa_M00130	Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4	0.889355996203675	-0.117257677951777	22	2	0.00174064403829417	1149	7161	23396,55361	PIP5K1C,PI4K2A
M00130	Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4	0.889355996203675	-0.117257677951777	22	2	0.00174064403829417	1149	7161	23396,55361	PIP5K1C,PI4K2A
ko05418	Fluid shear stress and atherosclerosis	0.891645295387952	-0.114686876396584	142	18	0.0156657963446475	1149	7161	7295,387,1728,208,5879,6613,5562,6383,4205,1432,1514,805,9817,5296,9181,596,60,4217	TXN,RHOA,NQO1,AKT2,RAC1,SUMO2,PRKAA1,SDC2,MEF2A,MAPK14,CTSL,CALM2,KEAP1,PIK3R2,ARHGEF2,BCL2,ACTB,MAP3K5
hsa05418	Fluid shear stress and atherosclerosis	0.891645295387952	-0.114686876396584	142	18	0.0156657963446475	1149	7161	7295,387,1728,208,5879,6613,5562,6383,4205,1432,1514,805,9817,5296,9181,596,60,4217	TXN,RHOA,NQO1,AKT2,RAC1,SUMO2,PRKAA1,SDC2,MEF2A,MAPK14,CTSL,CALM2,KEAP1,PIK3R2,ARHGEF2,BCL2,ACTB,MAP3K5
ko04724	Glutamatergic synapse	0.894490900184244	-0.111500549160297	114	14	0.0121845082680592	1149	7161	2778,5530,9456,156,2788,115,5534,5532,2771,5594,5566,2783,5595,113	GNAS,PPP3CA,HOMER1,GRK2,GNG7,ADCY9,PPP3R1,PPP3CB,GNAI2,MAPK1,PRKACA,GNB2,MAPK3,ADCY7
hsa04724	Glutamatergic synapse	0.894490900184244	-0.111500549160297	114	14	0.0121845082680592	1149	7161	2778,5530,9456,156,2788,115,5534,5532,2771,5594,5566,2783,5595,113	GNAS,PPP3CA,HOMER1,GRK2,GNG7,ADCY9,PPP3R1,PPP3CB,GNAI2,MAPK1,PRKACA,GNB2,MAPK3,ADCY7
ko05217	Basal cell carcinoma	0.895183818015154	-0.11072619853838	55	6	0.00522193211488251	1149	7161	1855,81029,8312,8323,1856,8313	DVL1,WNT5B,AXIN1,FZD6,DVL2,AXIN2
hsa05217	Basal cell carcinoma	0.895183818015154	-0.11072619853838	55	6	0.00522193211488251	1149	7161	1855,81029,8312,8323,1856,8313	DVL1,WNT5B,AXIN1,FZD6,DVL2,AXIN2
hsa04976	Bile secretion	0.902020357835786	-0.10311818951147	71	8	0.00696257615317668	1149	7161	2778,476,115,6513,6522,949,5566,113	GNAS,ATP1A1,ADCY9,SLC2A1,SLC4A2,SCARB1,PRKACA,ADCY7
ko04976	Bile secretion	0.902020357835786	-0.10311818951147	71	8	0.00696257615317668	1149	7161	2778,476,115,6513,6522,949,5566,113	GNAS,ATP1A1,ADCY9,SLC2A1,SLC4A2,SCARB1,PRKACA,ADCY7
ko00380	Tryptophan metabolism	0.90346042052694	-0.101522976741786	40	4	0.00348128807658834	1149	7161	38,847,4967,223	ACAT1,CAT,OGDH,ALDH9A1
hsa00380	Tryptophan metabolism	0.90346042052694	-0.101522976741786	40	4	0.00348128807658834	1149	7161	38,847,4967,223	ACAT1,CAT,OGDH,ALDH9A1
hsa04614	Renin-angiotensin system	0.903739381223863	-0.10121425526133	23	2	0.00174064403829417	1149	7161	57486,5476	NLN,CTSA
ko04614	Renin-angiotensin system	0.903739381223863	-0.10121425526133	23	2	0.00174064403829417	1149	7161	57486,5476	NLN,CTSA
ko05034	Alcoholism	0.908466534446914	-0.0959972278762029	180	23	0.0200174064403829	1149	7161	3015,4893,5894,2788,3845,2030,94239,5566,2783,5595,2778,805,6464,51564,3014,9555,1385,3020,5594,1386,2771,3265,3066	H2AFZ,NRAS,RAF1,GNG7,KRAS,SLC29A1,H2AFV,PRKACA,GNB2,MAPK3,GNAS,CALM2,SHC1,HDAC7,H2AFX,H2AFY,CREB1,H3F3A,MAPK1,ATF2,GNAI2,HRAS,HDAC2
hsa05034	Alcoholism	0.908466534446914	-0.0959972278762029	180	23	0.0200174064403829	1149	7161	3015,4893,5894,2788,3845,2030,94239,5566,2783,5595,2778,805,6464,51564,3014,9555,1385,3020,5594,1386,2771,3265,3066	H2AFZ,NRAS,RAF1,GNG7,KRAS,SLC29A1,H2AFV,PRKACA,GNB2,MAPK3,GNAS,CALM2,SHC1,HDAC7,H2AFX,H2AFY,CREB1,H3F3A,MAPK1,ATF2,GNAI2,HRAS,HDAC2
hsa05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	0.910042031986146	-0.0942644915421549	72	8	0.00696257615317668	1149	7161	782,3696,488,3688,60,3693,6443,4000	CACNB1,ITGB8,ATP2A2,ITGB1,ACTB,ITGB5,SGCB,LMNA
ko05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)	0.910042031986146	-0.0942644915421549	72	8	0.00696257615317668	1149	7161	782,3696,488,3688,60,3693,6443,4000	CACNB1,ITGB8,ATP2A2,ITGB1,ACTB,ITGB5,SGCB,LMNA
ko03320	PPAR signaling pathway	0.910042031986146	-0.0942644915421549	72	8	0.00696257615317668	1149	7161	5170,51703,10999,34,51,1622,2181,6257	PDPK1,ACSL5,SLC27A4,ACADM,ACOX1,DBI,ACSL3,RXRB
hsa03320	PPAR signaling pathway	0.910042031986146	-0.0942644915421549	72	8	0.00696257615317668	1149	7161	51703,10999,5170,34,51,2181,1622,6257	ACSL5,SLC27A4,PDPK1,ACADM,ACOX1,ACSL3,DBI,RXRB
ko05332	Graft-versus-host disease	0.913580054831235	-0.0903842717205876	41	4	0.00348128807658834	1149	7161	3106,3133,3105,355	HLA-B,HLA-E,HLA-A,FAS
hsa05332	Graft-versus-host disease	0.913580054831235	-0.0903842717205876	41	4	0.00348128807658834	1149	7161	3106,3133,3105,355	HLA-B,HLA-E,HLA-A,FAS
M00055	N-glycan precursor biosynthesis	0.91378596700488	-0.0901589067175666	14	1	0.000870322019147084	1149	7161	10195	ALG3
hsa_M00055	N-glycan precursor biosynthesis	0.91378596700488	-0.0901589067175666	14	1	0.000870322019147084	1149	7161	10195	ALG3
ko05321	Inflammatory bowel disease (IBD)	0.915101676354357	-0.0887200981814232	65	7	0.00609225413402959	1149	7161	7040,3594,4087,50615,6774,6778,6772	TGFB1,IL12RB1,SMAD2,IL21R,STAT3,STAT6,STAT1
hsa05321	Inflammatory bowel disease (IBD)	0.915101676354357	-0.0887200981814232	65	7	0.00609225413402959	1149	7161	7040,3594,4087,50615,6774,6778,6772	TGFB1,IL12RB1,SMAD2,IL21R,STAT3,STAT6,STAT1
hsa00340	Histidine metabolism	0.916360243782924	-0.0873457123830171	24	2	0.00174064403829417	1149	7161	221,223	ALDH3B1,ALDH9A1
ko00534	Glycosaminoglycan biosynthesis - heparan sulfate / heparin	0.916360243782924	-0.0873457123830171	24	2	0.00174064403829417	1149	7161	126792,2132	B3GALT6,EXT2
hsa00534	Glycosaminoglycan biosynthesis - heparan sulfate / heparin	0.916360243782924	-0.0873457123830171	24	2	0.00174064403829417	1149	7161	126792,2132	B3GALT6,EXT2
ko00340	Histidine metabolism	0.916360243782924	-0.0873457123830171	24	2	0.00174064403829417	1149	7161	221,223	ALDH3B1,ALDH9A1
hsa04913	Ovarian steroidogenesis	0.921164116313465	-0.0821170649928855	50	5	0.00435161009573542	1149	7161	2778,949,5566,115,113	GNAS,SCARB1,PRKACA,ADCY9,ADCY7
ko04913	Ovarian steroidogenesis	0.921164116313465	-0.0821170649928855	50	5	0.00435161009573542	1149	7161	2778,949,5566,115,113	GNAS,SCARB1,PRKACA,ADCY9,ADCY7
ko00860	Porphyrin and chlorophyll metabolism	0.922742744860407	-0.0804047996221405	42	4	0.00348128807658834	1149	7161	2058,1355,1371,7389	EPRS,COX15,CPOX,UROD
hsa00860	Porphyrin and chlorophyll metabolism	0.922742744860407	-0.0804047996221405	42	4	0.00348128807658834	1149	7161	1355,2058,1371,7389	COX15,EPRS,CPOX,UROD
hsa04918	Thyroid hormone synthesis	0.924416098910158	-0.0785929852098065	74	8	0.00696257615317668	1149	7161	2778,476,1385,1386,5566,7270,115,113	GNAS,ATP1A1,CREB1,ATF2,PRKACA,TTF1,ADCY9,ADCY7
ko04918	Thyroid hormone synthesis	0.924416098910158	-0.0785929852098065	74	8	0.00696257615317668	1149	7161	2778,476,1385,1386,5566,7270,115,113	GNAS,ATP1A1,CREB1,ATF2,PRKACA,TTF1,ADCY9,ADCY7
hsa_M00686	Toll-like receptor signaling	0.927646317354888	-0.0751047423819624	15	1	0.000870322019147084	1149	7161	23118	TAB2
hsa00730	Thiamine metabolism	0.927646317354888	-0.0751047423819624	15	1	0.000870322019147084	1149	7161	84284	NTPCR
ko00730	Thiamine metabolism	0.927646317354888	-0.0751047423819624	15	1	0.000870322019147084	1149	7161	84284	NTPCR
M00686	Toll-like receptor signaling	0.927646317354888	-0.0751047423819624	15	1	0.000870322019147084	1149	7161	23118	TAB2
ko04970	Salivary secretion	0.929207051774218	-0.0734236890335159	90	10	0.00870322019147084	1149	7161	2778,805,476,2983,115,6522,154,6558,5566,113	GNAS,CALM2,ATP1A1,GUCY1B1,ADCY9,SLC4A2,ADRB2,SLC12A2,PRKACA,ADCY7
hsa04970	Salivary secretion	0.929207051774218	-0.0734236890335159	90	10	0.00870322019147084	1149	7161	2778,805,476,2983,115,6522,154,6558,5566,113	GNAS,CALM2,ATP1A1,GUCY1B1,ADCY9,SLC4A2,ADRB2,SLC12A2,PRKACA,ADCY7
hsa04940	Type I diabetes mellitus	0.931023194179935	-0.0714710888253497	43	4	0.00348128807658834	1149	7161	3106,3133,3105,355	HLA-B,HLA-E,HLA-A,FAS
ko04940	Type I diabetes mellitus	0.931023194179935	-0.0714710888253497	43	4	0.00348128807658834	1149	7161	3106,3133,3105,355	HLA-B,HLA-E,HLA-A,FAS
hsa05032	Morphine addiction	0.934796091613165	-0.067426857313375	91	10	0.00870322019147084	1149	7161	2778,156,2788,115,5566,5140,409,2771,2783,113	GNAS,GRK2,GNG7,ADCY9,PRKACA,PDE3B,ARRB2,GNAI2,GNB2,ADCY7
ko05032	Morphine addiction	0.934796091613165	-0.067426857313375	91	10	0.00870322019147084	1149	7161	2778,156,2788,115,5566,5140,409,2771,2783,113	GNAS,GRK2,GNG7,ADCY9,PRKACA,PDE3B,ARRB2,GNAI2,GNB2,ADCY7
ko00350	Tyrosine metabolism	0.935848728143292	-0.0663014307972198	35	3	0.00261096605744125	1149	7161	4282,221,2806	MIF,ALDH3B1,GOT2
hsa00350	Tyrosine metabolism	0.935848728143292	-0.0663014307972198	35	3	0.00261096605744125	1149	7161	4282,221,2806	MIF,ALDH3B1,GOT2
M00683	Hippo signaling	0.939280011917184	-0.0626416419726072	16	1	0.000870322019147084	1149	7161	55233	MOB1A
hsa_M00683	Hippo signaling	0.939280011917184	-0.0626416419726072	16	1	0.000870322019147084	1149	7161	55233	MOB1A
hsa04911	Insulin secretion	0.943385436092313	-0.058280345931535	85	9	0.00783289817232376	1149	7161	2778,476,1385,1386,5566,818,115,6513,113	GNAS,ATP1A1,CREB1,ATF2,PRKACA,CAMK2G,ADCY9,SLC2A1,ADCY7
ko00500	Starch and sucrose metabolism	0.943486674299159	-0.058173037962558	36	3	0.00261096605744125	1149	7161	2821,2992,7360	GPI,GYG1,UGP2
hsa00500	Starch and sucrose metabolism	0.943486674299159	-0.058173037962558	36	3	0.00261096605744125	1149	7161	2821,2992,7360	GPI,GYG1,UGP2
ko00565	Ether lipid metabolism	0.945219277284107	-0.0563383389513034	45	4	0.00348128807658834	1149	7161	23646,79888,56994,254531	PLD3,LPCAT1,CHPT1,LPCAT4
hsa00565	Ether lipid metabolism	0.945219277284107	-0.0563383389513034	45	4	0.00348128807658834	1149	7161	23646,56994,79888,254531	PLD3,CHPT1,LPCAT1,LPCAT4
hsa00910	Nitrogen metabolism	0.94904449986466	-0.0522995901494867	17	1	0.000870322019147084	1149	7161	2746	GLUD1
hsa_M00003	Gluconeogenesis, oxaloacetate => fructose-6P	0.94904449986466	-0.0522995901494867	17	1	0.000870322019147084	1149	7161	5223	PGAM1
ko00910	Nitrogen metabolism	0.94904449986466	-0.0522995901494867	17	1	0.000870322019147084	1149	7161	2746	GLUD1
M00003	Gluconeogenesis, oxaloacetate => fructose-6P	0.94904449986466	-0.0522995901494867	17	1	0.000870322019147084	1149	7161	5223	PGAM1
hsa00983	Drug metabolism - other enzymes	0.951266596676999	-0.0499609227290086	46	4	0.00348128807658834	1149	7161	3614,83549,7083,7371	IMPDH1,UCK1,TK1,UCK2
ko00983	Drug metabolism - other enzymes	0.951266596676999	-0.0499609227290086	46	4	0.00348128807658834	1149	7161	3614,83549,7083,7371	IMPDH1,UCK1,TK1,UCK2
hsa05134	Legionellosis	0.95382350509236	-0.0472766297936896	55	5	0.00435161009573542	1149	7161	54205,375,5861,56681,3304	CYCS,ARF1,RAB1A,SAR1A,HSPA1B
ko05134	Legionellosis	0.95382350509236	-0.0472766297936896	55	5	0.00435161009573542	1149	7161	54205,375,5861,56681,3304	CYCS,ARF1,RAB1A,SAR1A,HSPA1B
hsa04726	Serotonergic synapse	0.959412548722576	-0.0414341102388458	112	12	0.010443864229765	1149	7161	2778,4893,5894,2788,3845,5594,5566,2771,2783,3265,351,5595	GNAS,NRAS,RAF1,GNG7,KRAS,MAPK1,PRKACA,GNAI2,GNB2,HRAS,APP,MAPK3
ko05206	MicroRNAs in cancer	0.970845224666847	-0.0295882212674273	299	37	0.0322019147084421	1149	7161	1788,5894,9493,4853,7329,3925,1399,2261,4193,6464,5728,5296,1027,596,994,6774,1786,4363,578,4893,387,1871,7430,4170,3845,672,6659,5605,100532731,113130,1869,6093,5594,1870,3265,1029,27250	DNMT3A,RAF1,KIF23,NOTCH2,UBE2I,STMN1,CRKL,FGFR3,MDM2,SHC1,PTEN,PIK3R2,CDKN1B,BCL2,CDC25B,STAT3,DNMT1,ABCC1,BAK1,NRAS,RHOA,E2F3,EZR,MCL1,KRAS,BRCA1,SOX4,MAP2K2,COMMD3-BMI1,CDCA5,E2F1,ROCK1,MAPK1,E2F2,HRAS,CDKN2A,PDCD4
hsa05206	MicroRNAs in cancer	0.970845224666847	-0.0295882212674273	299	37	0.0322019147084421	1149	7161	1788,5894,9493,4853,7329,3925,1399,2261,4193,6464,5728,5296,1027,596,994,6774,1786,4363,578,4893,387,1871,7430,4170,3845,672,6659,5605,100532731,113130,1869,6093,5594,1870,3265,1029,27250	DNMT3A,RAF1,KIF23,NOTCH2,UBE2I,STMN1,CRKL,FGFR3,MDM2,SHC1,PTEN,PIK3R2,CDKN1B,BCL2,CDC25B,STAT3,DNMT1,ABCC1,BAK1,NRAS,RHOA,E2F3,EZR,MCL1,KRAS,BRCA1,SOX4,MAP2K2,COMMD3-BMI1,CDCA5,E2F1,ROCK1,MAPK1,E2F2,HRAS,CDKN2A,PDCD4
hsa04657	IL-17 signaling pathway	0.972696121863332	-0.0276835560959471	93	9	0.00783289817232376	1149	7161	7128,23118,5597,5594,7188,1432,8772,5595,6426	TNFAIP3,TAB2,MAPK6,MAPK1,TRAF5,MAPK14,FADD,MAPK3,SRSF1
ko04657	IL-17 signaling pathway	0.972696121863332	-0.0276835560959471	93	9	0.00783289817232376	1149	7161	7128,23118,5597,5594,7188,1432,8772,5595,6426	TNFAIP3,TAB2,MAPK6,MAPK1,TRAF5,MAPK14,FADD,MAPK3,SRSF1
hsa04978	Mineral absorption	0.97327814298946	-0.0270853764036504	51	4	0.00348128807658834	1149	7161	2512,1317,476,65010	FTL,SLC31A1,ATP1A1,SLC26A6
ko04978	Mineral absorption	0.97327814298946	-0.0270853764036504	51	4	0.00348128807658834	1149	7161	2512,1317,476,65010	FTL,SLC31A1,ATP1A1,SLC26A6
hsa05320	Autoimmune thyroid disease	0.97637403910831	-0.0239095291942061	52	4	0.00348128807658834	1149	7161	3106,3133,3105,355	HLA-B,HLA-E,HLA-A,FAS
ko05320	Autoimmune thyroid disease	0.97637403910831	-0.0239095291942061	52	4	0.00348128807658834	1149	7161	3106,3133,3105,355	HLA-B,HLA-E,HLA-A,FAS
hsa04151	PI3K-Akt signaling pathway	0.979864046642995	-0.020341444856438	341	42	0.0365535248041775	1149	7161	7249,5894,5879,5562,598,3693,2309,2783,2261,4193,3696,5728,5296,1027,596,1385,2149,1386,11140,64223,5170,4893,208,2788,4170,3845,672,5605,6009,5595,5515,7248,3716,5525,3688,7534,6794,5594,7533,1017,55844,3265	TSC2,RAF1,RAC1,PRKAA1,BCL2L1,ITGB5,FOXO3,GNB2,FGFR3,MDM2,ITGB8,PTEN,PIK3R2,CDKN1B,BCL2,CREB1,F2R,ATF2,CDC37,MLST8,PDPK1,NRAS,AKT2,GNG7,MCL1,KRAS,BRCA1,MAP2K2,RHEB,MAPK3,PPP2CA,TSC1,JAK1,PPP2R5A,ITGB1,YWHAZ,STK11,MAPK1,YWHAH,CDK2,PPP2R2D,HRAS
ko04151	PI3K-Akt signaling pathway	0.979864046642995	-0.020341444856438	341	42	0.0365535248041775	1149	7161	7249,5894,5879,5562,598,3693,2309,2783,2261,4193,3696,5728,5296,1027,596,1385,2149,1386,11140,64223,5170,4893,208,2788,4170,3845,672,5605,6009,5595,5515,7248,3716,5525,3688,7534,6794,5594,7533,1017,55844,3265	TSC2,RAF1,RAC1,PRKAA1,BCL2L1,ITGB5,FOXO3,GNB2,FGFR3,MDM2,ITGB8,PTEN,PIK3R2,CDKN1B,BCL2,CREB1,F2R,ATF2,CDC37,MLST8,PDPK1,NRAS,AKT2,GNG7,MCL1,KRAS,BRCA1,MAP2K2,RHEB,MAPK3,PPP2CA,TSC1,JAK1,PPP2R5A,ITGB1,YWHAZ,STK11,MAPK1,YWHAH,CDK2,PPP2R2D,HRAS
hsa04727	GABAergic synapse	0.979962445990752	-0.020241028469365	88	8	0.00696257615317668	1149	7161	92745,4905,2771,5566,2783,2788,115,113	SLC38A5,NSF,GNAI2,PRKACA,GNB2,GNG7,ADCY9,ADCY7
ko04727	GABAergic synapse	0.979962445990752	-0.020241028469365	88	8	0.00696257615317668	1149	7161	92745,4905,2771,5566,2783,2788,115,113	SLC38A5,NSF,GNAI2,PRKACA,GNB2,GNG7,ADCY9,ADCY7
ko04973	Carbohydrate digestion and absorption	0.980266289923647	-0.0199310198160263	44	3	0.00261096605744125	1149	7161	476,208,5296	ATP1A1,AKT2,PIK3R2
hsa04973	Carbohydrate digestion and absorption	0.980266289923647	-0.0199310198160263	44	3	0.00261096605744125	1149	7161	476,208,5296	ATP1A1,AKT2,PIK3R2
ko05143	African trypanosomiasis	0.980589645852595	-0.019601208812598	34	2	0.00174064403829417	1149	7161	8542,355	APOL1,FAS
hsa05143	African trypanosomiasis	0.980589645852595	-0.019601208812598	34	2	0.00174064403829417	1149	7161	8542,355	APOL1,FAS
ko00040	Pentose and glucuronate interconversions	0.980589645852595	-0.019601208812598	34	2	0.00174064403829417	1149	7161	231,7360	AKR1B1,UGP2
hsa00040	Pentose and glucuronate interconversions	0.980589645852595	-0.019601208812598	34	2	0.00174064403829417	1149	7161	231,7360	AKR1B1,UGP2
ko00592	alpha-Linolenic acid metabolism	0.987478783808577	-0.0126002671884692	25	1	0.000870322019147084	1149	7161	51	ACOX1
hsa00592	alpha-Linolenic acid metabolism	0.987478783808577	-0.0126002671884692	25	1	0.000870322019147084	1149	7161	51	ACOX1
ko04723	Retrograde endocannabinoid signaling	0.987503039770209	-0.0125757039632853	101	9	0.00783289817232376	1149	7161	2788,115,5594,5566,2771,1432,2783,5595,113	GNG7,ADCY9,MAPK1,PRKACA,GNAI2,MAPK14,GNB2,MAPK3,ADCY7
hsa04723	Retrograde endocannabinoid signaling	0.987503039770209	-0.0125757039632853	101	9	0.00783289817232376	1149	7161	2788,115,5594,5566,2771,1432,2783,5595,113	GNG7,ADCY9,MAPK1,PRKACA,GNAI2,MAPK14,GNB2,MAPK3,ADCY7
ko04020	Calcium signaling pathway	0.988163573190309	-0.0119070350285789	181	19	0.0165361183637946	1149	7161	10105,5530,80228,7417,5532,154,7416,5566,292,805,2778,488,115,5534,84876,2149,5261,818,113	PPIF,PPP3CA,ORAI2,VDAC2,PPP3CB,ADRB2,VDAC1,PRKACA,SLC25A5,CALM2,GNAS,ATP2A2,ADCY9,PPP3R1,ORAI1,F2R,PHKG2,CAMK2G,ADCY7
hsa04020	Calcium signaling pathway	0.988163573190309	-0.0119070350285789	181	19	0.0165361183637946	1149	7161	10105,5530,80228,7417,5532,154,7416,292,5566,805,2778,488,115,5534,84876,2149,5261,818,113	PPIF,PPP3CA,ORAI2,VDAC2,PPP3CB,ADRB2,VDAC1,SLC25A5,PRKACA,CALM2,GNAS,ATP2A2,ADCY9,PPP3R1,ORAI1,F2R,PHKG2,CAMK2G,ADCY7
hsa04950	Maturity onset diabetes of the young	0.989494882111965	-0.0105606861489864	26	1	0.000870322019147084	1149	7161	3087	HHEX
ko04950	Maturity onset diabetes of the young	0.989494882111965	-0.0105606861489864	26	1	0.000870322019147084	1149	7161	3087	HHEX
hsa05144	Malaria	0.990062765943695	-0.00998693792006646	49	3	0.00261096605744125	1149	7161	7040,975,6383	TGFB1,CD81,SDC2
ko05144	Malaria	0.990062765943695	-0.00998693792006646	49	3	0.00261096605744125	1149	7161	7040,975,6383	TGFB1,CD81,SDC2
ko00260	Glycine, serine and threonine metabolism	0.990908945910681	-0.00913262989195402	39	2	0.00174064403829417	1149	7161	5223,2653	PGAM1,GCSH
hsa00260	Glycine, serine and threonine metabolism	0.990908945910681	-0.00913262989195402	39	2	0.00174064403829417	1149	7161	5223,2653	PGAM1,GCSH
hsa00053	Ascorbate and aldarate metabolism	0.991186596266083	-0.0088524714926135	27	1	0.000870322019147084	1149	7161	223	ALDH9A1
ko00053	Ascorbate and aldarate metabolism	0.991186596266083	-0.0088524714926135	27	1	0.000870322019147084	1149	7161	223	ALDH9A1
hsa04750	Inflammatory mediator regulation of TRP channels	0.992167112188882	-0.00786372601720995	97	8	0.00696257615317668	1149	7161	2778,805,5296,115,5566,1432,818,113	GNAS,CALM2,PIK3R2,ADCY9,PRKACA,MAPK14,CAMK2G,ADCY7
ko04750	Inflammatory mediator regulation of TRP channels	0.992167112188882	-0.00786372601720995	97	8	0.00696257615317668	1149	7161	2778,805,5296,115,5566,1432,818,113	GNAS,CALM2,PIK3R2,ADCY9,PRKACA,MAPK14,CAMK2G,ADCY7
ko04744	Phototransduction	0.992606080553115	-0.00742138996289788	28	1	0.000870322019147084	1149	7161	805	CALM2
hsa04744	Phototransduction	0.992606080553115	-0.00742138996289788	28	1	0.000870322019147084	1149	7161	805	CALM2
hsa04392	Hippo signaling pathway -multiple species	0.993797110066982	-0.00622220778052974	29	1	0.000870322019147084	1149	7161	55233	MOB1A
ko04392	Hippo signaling pathway -multiple species	0.993797110066982	-0.00622220778052974	29	1	0.000870322019147084	1149	7161	55233	MOB1A
ko04672	Intestinal immune network for IgA production	0.997371044597052	-0.00263241717476324	47	2	0.00174064403829417	1149	7161	7040,9020	TGFB1,MAP3K14
hsa04672	Intestinal immune network for IgA production	0.997371044597052	-0.00263241717476324	47	2	0.00174064403829417	1149	7161	7040,9020	TGFB1,MAP3K14
hsa00590	Arachidonic acid metabolism	0.998451633808931	-0.00154956614880915	62	3	0.00261096605744125	1149	7161	10728,4048,2053	PTGES3,LTA4H,EPHX2
ko00590	Arachidonic acid metabolism	0.998451633808931	-0.00154956614880915	62	3	0.00261096605744125	1149	7161	10728,4048,2053	PTGES3,LTA4H,EPHX2
hsa05146	Amoebiasis	0.998683077210544	-0.00131779069433195	94	6	0.00522193211488251	1149	7161	2778,7040,5869,5566,7879,5296	GNAS,TGFB1,RAB5B,PRKACA,RAB7A,PIK3R2
ko05146	Amoebiasis	0.998683077210544	-0.00131779069433195	94	6	0.00522193211488251	1149	7161	2778,7040,5869,5566,7879,5296	GNAS,TGFB1,RAB5B,PRKACA,RAB7A,PIK3R2
ko04514	Cell adhesion molecules (CAMs)	0.999076782997399	-0.000923643429894857	143	11	0.00957354221061793	1149	7161	5792,3106,3696,6404,3133,2734,6383,3688,23705,3384,3105	PTPRF,HLA-B,ITGB8,SELPLG,HLA-E,GLG1,SDC2,ITGB1,CADM1,ICAM2,HLA-A
hsa04514	Cell adhesion molecules (CAMs)	0.999076782997399	-0.000923643429894857	143	11	0.00957354221061793	1149	7161	5792,3106,3696,6404,3133,2734,6383,3688,23705,3384,3105	PTPRF,HLA-B,ITGB8,SELPLG,HLA-E,GLG1,SDC2,ITGB1,CADM1,ICAM2,HLA-A
hsa04512	ECM-receptor interaction	0.999576535092418	-0.000423554594165908	82	4	0.00348128807658834	1149	7161	375790,3696,3693,3688	AGRN,ITGB8,ITGB5,ITGB1
ko04512	ECM-receptor interaction	0.999576535092418	-0.000423554594165908	82	4	0.00348128807658834	1149	7161	375790,3696,3693,3688	AGRN,ITGB8,ITGB5,ITGB1
hsa00830	Retinol metabolism	0.999851810446756	-0.000148200534400825	65	2	0.00174064403829417	1149	7161	157506,51109	RDH10,RDH11
ko00830	Retinol metabolism	0.999851810446756	-0.000148200534400825	65	2	0.00174064403829417	1149	7161	157506,51109	RDH10,RDH11
ko04610	Complement and coagulation cascades	0.999878902278209	-0.000121105054711731	79	3	0.00261096605744125	1149	7161	966,1191,2149	CD59,CLU,F2R
hsa04610	Complement and coagulation cascades	0.999878902278209	-0.000121105054711731	79	3	0.00261096605744125	1149	7161	966,1191,2149	CD59,CLU,F2R
ko00982	Drug metabolism - cytochrome P450	0.999922690985571	-7.73120029246157e-05	69	2	0.00174064403829417	1149	7161	373156,221	GSTK1,ALDH3B1
hsa00982	Drug metabolism - cytochrome P450	0.999922690985571	-7.73120029246157e-05	69	2	0.00174064403829417	1149	7161	373156,221	GSTK1,ALDH3B1
hsa05150	Staphylococcus aureus infection	0.999936146801023	-6.38552376792939e-05	55	1	0.000870322019147084	1149	7161	6404	SELPLG
ko05150	Staphylococcus aureus infection	0.999936146801023	-6.38552376792939e-05	55	1	0.000870322019147084	1149	7161	6404	SELPLG
hsa00980	Metabolism of xenobiotics by cytochrome P450	0.999959803265028	-4.01975428825925e-05	73	2	0.00174064403829417	1149	7161	373156,221	GSTK1,ALDH3B1
ko00980	Metabolism of xenobiotics by cytochrome P450	0.999959803265028	-4.01975428825925e-05	73	2	0.00174064403829417	1149	7161	373156,221	GSTK1,ALDH3B1
hsa05322	Systemic lupus erythematosus	0.999965242773387	-3.47578306590538e-05	132	7	0.00609225413402959	1149	7161	9555,3015,3020,6634,94239,6628,3014	H2AFY,H2AFZ,H3F3A,SNRPD3,H2AFV,SNRPB,H2AFX
ko05322	Systemic lupus erythematosus	0.999965242773387	-3.47578306590538e-05	132	7	0.00609225413402959	1149	7161	9555,3015,3020,6634,94239,6628,3014	H2AFY,H2AFZ,H3F3A,SNRPD3,H2AFV,SNRPB,H2AFX
hsa05204	Chemical carcinogenesis	0.999990871159678	-9.12888199037795e-06	82	2	0.00174064403829417	1149	7161	373156,221	GSTK1,ALDH3B1
ko05204	Chemical carcinogenesis	0.999990871159678	-9.12888199037795e-06	82	2	0.00174064403829417	1149	7161	373156,221	GSTK1,ALDH3B1
hsa04974	Protein digestion and absorption	0.999997143892555	-2.8561115235277e-06	89	2	0.00174064403829417	1149	7161	476,3784	ATP1A1,KCNQ1
ko04974	Protein digestion and absorption	0.999997143892555	-2.8561115235277e-06	89	2	0.00174064403829417	1149	7161	476,3784	ATP1A1,KCNQ1
ko04640	Hematopoietic cell lineage	0.99999911255353	-8.87446863946136e-07	96	2	0.00174064403829417	1149	7161	966,7037	CD59,TFRC
hsa04640	Hematopoietic cell lineage	0.99999911255353	-8.87446863946136e-07	96	2	0.00174064403829417	1149	7161	966,7037	CD59,TFRC
ko04742	Taste transduction	0.999999459406436	-5.40593710036753e-07	82	1	0.000870322019147084	1149	7161	5566	PRKACA
hsa04742	Taste transduction	0.999999459406436	-5.40593710036753e-07	82	1	0.000870322019147084	1149	7161	5566	PRKACA
hsa04740	Olfactory transduction	0.999999999937805	-6.21952679471209e-11	415	7	0.00609225413402959	1149	7161	805,156,5997,5566,409,818,2788	CALM2,GRK2,RGS2,PRKACA,ARRB2,CAMK2G,GNG7
ko04740	Olfactory transduction	0.999999999937805	-6.21952679471209e-11	415	7	0.00609225413402959	1149	7161	805,156,5997,5566,409,818,2788	CALM2,GRK2,RGS2,PRKACA,ARRB2,CAMK2G,GNG7
hsa04060	Cytokine-cytokine receptor interaction	0.999999999975451	-2.4548892924873e-11	270	5	0.00435161009573542	1149	7161	7040,3594,50615,3572,355	TGFB1,IL12RB1,IL21R,IL6ST,FAS
ko04060	Cytokine-cytokine receptor interaction	0.999999999975451	-2.4548892924873e-11	270	5	0.00435161009573542	1149	7161	7040,3594,50615,3572,355	TGFB1,IL12RB1,IL21R,IL6ST,FAS
ko04080	Neuroactive ligand-receptor interaction	0.999999999980047	-1.99526936165927e-11	276	4	0.00348128807658834	1149	7161	154,9294,2149,56288	ADRB2,S1PR2,F2R,PARD3
hsa04080	Neuroactive ligand-receptor interaction	0.999999999980047	-1.99526936165927e-11	276	4	0.00348128807658834	1149	7161	154,9294,2149,56288	ADRB2,S1PR2,F2R,PARD3
hsa_M00399	Cap binding complex	0.999999999988648	-1.13516036848171e-11	2	0	0	1149	7161
hsa00300	Lysine biosynthesis	0.999999999988648	-1.13516036848171e-11	2	0	0	1149	7161
M00103	Cholecalciferol biosynthesis	0.999999999988648	-1.13516036848171e-11	2	0	0	1149	7161
M00338	Cysteine biosynthesis, homocysteine + serine => cysteine	0.999999999988648	-1.13516036848171e-11	2	0	0	1149	7161
hsa_M00338	Cysteine biosynthesis, homocysteine + serine => cysteine	0.999999999988648	-1.13516036848171e-11	2	0	0	1149	7161
hsa_M00083	Fatty acid biosynthesis, elongation	0.999999999988648	-1.13516036848171e-11	2	0	0	1149	7161
hsa_M00103	Cholecalciferol biosynthesis	0.999999999988648	-1.13516036848171e-11	2	0	0	1149	7161
M00083	Fatty acid biosynthesis, elongation	0.999999999988648	-1.13516036848171e-11	2	0	0	1149	7161
hsa_M00066	Lactosylceramide biosynthesis	0.999999999988648	-1.13516036848171e-11	2	0	0	1149	7161
M00106	Conjugated bile acid biosynthesis, cholate => taurocholate/glycocholate	0.999999999988648	-1.13516036848171e-11	2	0	0	1149	7161
M00066	Lactosylceramide biosynthesis	0.999999999988648	-1.13516036848171e-11	2	0	0	1149	7161
M00399	Cap binding complex	0.999999999988648	-1.13516036848171e-11	2	0	0	1149	7161
ko00300	Lysine biosynthesis	0.999999999988648	-1.13516036848171e-11	2	0	0	1149	7161
M00067	Sulfoglycolipids biosynthesis, ceramide/1-alkyl-2-acylglycerol => sulfatide/seminolipid	0.999999999988648	-1.13516036848171e-11	2	0	0	1149	7161
M00068	Glycosphingolipid biosynthesis, globo-series, LacCer => Gb4Cer	0.999999999988648	-1.13516036848171e-11	2	0	0	1149	7161
hsa_M00067	Sulfoglycolipids biosynthesis, ceramide/1-alkyl-2-acylglycerol => sulfatide/seminolipid	0.999999999988648	-1.13516036848171e-11	2	0	0	1149	7161
hsa_M00068	Glycosphingolipid biosynthesis, globo-series, LacCer => Gb4Cer	0.999999999988648	-1.13516036848171e-11	2	0	0	1149	7161
hsa_M00106	Conjugated bile acid biosynthesis, cholate => taurocholate/glycocholate	0.999999999988648	-1.13516036848171e-11	2	0	0	1149	7161
ko00785	Lipoic acid metabolism	0.999999999996251	-3.74917284717835e-12	3	0	0	1149	7161
hsa_M00069	Glycosphingolipid biosynthesis, ganglio series, LacCer => GT3	0.999999999996251	-3.74917284717835e-12	3	0	0	1149	7161
hsa_M00082	Fatty acid biosynthesis, initiation	0.999999999996251	-3.74917284717835e-12	3	0	0	1149	7161
hsa_M00392	Ski complex	0.999999999996251	-3.74917284717835e-12	3	0	0	1149	7161
M00046	Pyrimidine degradation, uracil => beta-alanine, thymine => 3-aminoisobutanoate	0.999999999996251	-3.74917284717835e-12	3	0	0	1149	7161
hsa00780	Biotin metabolism	0.999999999996251	-3.74917284717835e-12	3	0	0	1149	7161
hsa_M00108	C21-Steroid hormone biosynthesis, progesterone => corticosterone/aldosterone	0.999999999996251	-3.74917284717835e-12	3	0	0	1149	7161
M00392	Ski complex	0.999999999996251	-3.74917284717835e-12	3	0	0	1149	7161
M00108	C21-Steroid hormone biosynthesis, progesterone => corticosterone/aldosterone	0.999999999996251	-3.74917284717835e-12	3	0	0	1149	7161
M00020	Serine biosynthesis, glycerate-3P => serine	0.999999999996251	-3.74917284717835e-12	3	0	0	1149	7161
hsa_M00132	Inositol phosphate metabolism, Ins(1,3,4)P3 => phytate	0.999999999996251	-3.74917284717835e-12	3	0	0	1149	7161
hsa_M00020	Serine biosynthesis, glycerate-3P => serine	0.999999999996251	-3.74917284717835e-12	3	0	0	1149	7161
M00082	Fatty acid biosynthesis, initiation	0.999999999996251	-3.74917284717835e-12	3	0	0	1149	7161
hsa_M00291	MRN complex	0.999999999996251	-3.74917284717835e-12	3	0	0	1149	7161
hsa00785	Lipoic acid metabolism	0.999999999996251	-3.74917284717835e-12	3	0	0	1149	7161
hsa_M00046	Pyrimidine degradation, uracil => beta-alanine, thymine => 3-aminoisobutanoate	0.999999999996251	-3.74917284717835e-12	3	0	0	1149	7161
hsa_M00051	Uridine monophosphate biosynthesis, glutamine (+ PRPP) => UMP	0.999999999996251	-3.74917284717835e-12	3	0	0	1149	7161
M00291	MRN complex	0.999999999996251	-3.74917284717835e-12	3	0	0	1149	7161
M00107	Steroid hormone biosynthesis, cholesterol => prognenolone => progesterone	0.999999999996251	-3.74917284717835e-12	3	0	0	1149	7161
M00100	Sphingosine degradation	0.999999999996251	-3.74917284717835e-12	3	0	0	1149	7161
ko00780	Biotin metabolism	0.999999999996251	-3.74917284717835e-12	3	0	0	1149	7161
M00051	Uridine monophosphate biosynthesis, glutamine (+ PRPP) => UMP	0.999999999996251	-3.74917284717835e-12	3	0	0	1149	7161
hsa_M00107	Steroid hormone biosynthesis, cholesterol => prognenolone => progesterone	0.999999999996251	-3.74917284717835e-12	3	0	0	1149	7161
hsa_M00100	Sphingosine degradation	0.999999999996251	-3.74917284717835e-12	3	0	0	1149	7161
M00069	Glycosphingolipid biosynthesis, ganglio series, LacCer => GT3	0.999999999996251	-3.74917284717835e-12	3	0	0	1149	7161
M00132	Inositol phosphate metabolism, Ins(1,3,4)P3 => phytate	0.999999999996251	-3.74917284717835e-12	3	0	0	1149	7161
M00037	Melatonin biosynthesis, tryptophan => serotonin => melatonin	0.99999999999786	-2.13965784922731e-12	5	0	0	1149	7161
ko00232	Caffeine metabolism	0.99999999999786	-2.13965784922731e-12	5	0	0	1149	7161
hsa_M00042	Catecholamine biosynthesis, tyrosine => dopamine => noradrenaline => adrenaline	0.99999999999786	-2.13965784922731e-12	5	0	0	1149	7161
hsa_M00128	Ubiquinone biosynthesis, eukaryotes, 4-hydroxybenzoate => ubiquinone	0.99999999999786	-2.13965784922731e-12	5	0	0	1149	7161
M00042	Catecholamine biosynthesis, tyrosine => dopamine => noradrenaline => adrenaline	0.99999999999786	-2.13965784922731e-12	5	0	0	1149	7161
M00307	Pyruvate oxidation, pyruvate => acetyl-CoA	0.99999999999786	-2.13965784922731e-12	5	0	0	1149	7161
hsa00524	Neomycin, kanamycin and gentamicin biosynthesis	0.99999999999786	-2.13965784922731e-12	5	0	0	1149	7161
hsa_M00044	Tyrosine degradation, tyrosine => homogentisate	0.99999999999786	-2.13965784922731e-12	5	0	0	1149	7161
hsa_M00037	Melatonin biosynthesis, tryptophan => serotonin => melatonin	0.99999999999786	-2.13965784922731e-12	5	0	0	1149	7161
M00128	Ubiquinone biosynthesis, eukaryotes, 4-hydroxybenzoate => ubiquinone	0.99999999999786	-2.13965784922731e-12	5	0	0	1149	7161
ko00524	Neomycin, kanamycin and gentamicin biosynthesis	0.99999999999786	-2.13965784922731e-12	5	0	0	1149	7161
M00044	Tyrosine degradation, tyrosine => homogentisate	0.99999999999786	-2.13965784922731e-12	5	0	0	1149	7161
hsa00232	Caffeine metabolism	0.99999999999786	-2.13965784922731e-12	5	0	0	1149	7161
hsa_M00307	Pyruvate oxidation, pyruvate => acetyl-CoA	0.99999999999786	-2.13965784922731e-12	5	0	0	1149	7161
hsa_M00685	Apoptotic machinery	0.999999999998769	-1.23055331115868e-12	4	0	0	1149	7161
hsa_M00262	DNA polymerase delta complex	0.999999999998769	-1.23055331115868e-12	4	0	0	1149	7161
hsa_M00006	Pentose phosphate pathway, oxidative phase, glucose 6P => ribulose 5P	0.999999999998769	-1.23055331115868e-12	4	0	0	1149	7161
M00006	Pentose phosphate pathway, oxidative phase, glucose 6P => ribulose 5P	0.999999999998769	-1.23055331115868e-12	4	0	0	1149	7161
hsa_M00027	GABA (gamma-Aminobutyrate) shunt	0.999999999998769	-1.23055331115868e-12	4	0	0	1149	7161
M00393	TRAMP complex	0.999999999998769	-1.23055331115868e-12	4	0	0	1149	7161
M00110	C19/C18-Steroid hormone biosynthesis, pregnenolone => androstenedione => estrone	0.999999999998769	-1.23055331115868e-12	4	0	0	1149	7161
M00070	Glycosphingolipid biosynthesis, lacto-series, LacCer => Lc4Cer	0.999999999998769	-1.23055331115868e-12	4	0	0	1149	7161
hsa_M00070	Glycosphingolipid biosynthesis, lacto-series, LacCer => Lc4Cer	0.999999999998769	-1.23055331115868e-12	4	0	0	1149	7161
M00690	MAPK (ERK5) signaling	0.999999999998769	-1.23055331115868e-12	4	0	0	1149	7161
M00027	GABA (gamma-Aminobutyrate) shunt	0.999999999998769	-1.23055331115868e-12	4	0	0	1149	7161
hsa_M00393	TRAMP complex	0.999999999998769	-1.23055331115868e-12	4	0	0	1149	7161
M00262	DNA polymerase delta complex	0.999999999998769	-1.23055331115868e-12	4	0	0	1149	7161
hsa_M00690	MAPK (ERK5) signaling	0.999999999998769	-1.23055331115868e-12	4	0	0	1149	7161
hsa_M00110	C19/C18-Steroid hormone biosynthesis, pregnenolone => androstenedione => estrone	0.999999999998769	-1.23055331115868e-12	4	0	0	1149	7161
M00685	Apoptotic machinery	0.999999999998769	-1.23055331115868e-12	4	0	0	1149	7161
M00091	Phosphatidylcholine (PC) biosynthesis, PE => PC	0.999999999999425	-5.75400838087603e-13	1	0	0	1149	7161
hsa00472	D-Arginine and D-ornithine metabolism	0.999999999999425	-5.75400838087603e-13	1	0	0	1149	7161
ko00472	D-Arginine and D-ornithine metabolism	0.999999999999425	-5.75400838087603e-13	1	0	0	1149	7161
hsa_M00043	Thyroid hormone biosynthesis, tyrosine => triiodothyronine/thyroxine	0.999999999999425	-5.75400838087603e-13	1	0	0	1149	7161
M00043	Thyroid hormone biosynthesis, tyrosine => triiodothyronine/thyroxine	0.999999999999425	-5.75400838087603e-13	1	0	0	1149	7161
hsa_M00091	Phosphatidylcholine (PC) biosynthesis, PE => PC	0.999999999999425	-5.75400838087603e-13	1	0	0	1149	7161
hsa_M00047	Creatine pathway	1.00000000000474	4.74227643602776e-12	7	0	0	1149	7161
M00047	Creatine pathway	1.00000000000474	4.74227643602776e-12	7	0	0	1149	7161
M00076	Dermatan sulfate degradation	1.00000000000807	8.07352639885159e-12	9	0	0	1149	7161
hsa_M00076	Dermatan sulfate degradation	1.00000000000807	8.07352639885159e-12	9	0	0	1149	7161
hsa_M00077	Chondroitin sulfate degradation	1.00000000001021	1.02100084847081e-11	8	0	0	1149	7161
hsa_M00409	ESCRT-I complex	1.00000000001021	1.02100084847081e-11	8	0	0	1149	7161
M00077	Chondroitin sulfate degradation	1.00000000001021	1.02100084847081e-11	8	0	0	1149	7161
M00409	ESCRT-I complex	1.00000000001021	1.02100084847081e-11	8	0	0	1149	7161
M00109	C21-Steroid hormone biosynthesis, progesterone => cortisol/cortisone	1.00000000001052	1.05153406869483e-11	6	0	0	1149	7161
M00029	Urea cycle	1.00000000001052	1.05153406869483e-11	6	0	0	1149	7161
hsa_M00109	C21-Steroid hormone biosynthesis, progesterone => cortisol/cortisone	1.00000000001052	1.05153406869483e-11	6	0	0	1149	7161
hsa_M00029	Urea cycle	1.00000000001052	1.05153406869483e-11	6	0	0	1149	7161
hsa_M00678	Hedgehog signaling	1.00000000001386	1.38576738860206e-11	11	0	0	1149	7161
M00678	Hedgehog signaling	1.00000000001386	1.38576738860206e-11	11	0	0	1149	7161
hsa_M00098	Acylglycerol degradation	1.00000000001386	1.38576738860206e-11	11	0	0	1149	7161
M00098	Acylglycerol degradation	1.00000000001386	1.38576738860206e-11	11	0	0	1149	7161
M00104	Bile acid biosynthesis, cholesterol => cholate/chenodeoxycholate	1.00000000002158	2.15850042948269e-11	12	0	0	1149	7161
hsa_M00104	Bile acid biosynthesis, cholesterol => cholate/chenodeoxycholate	1.00000000002158	2.15850042948269e-11	12	0	0	1149	7161
ko00120	Primary bile acid biosynthesis	1.00000000002169	2.16889091768707e-11	17	0	0	1149	7161
hsa00120	Primary bile acid biosynthesis	1.00000000002169	2.16889091768707e-11	17	0	0	1149	7161
hsa05310	Asthma	1.00000000003004	3.00405434782873e-11	30	0	0	1149	7161
ko05310	Asthma	1.00000000003004	3.00405434782873e-11	30	0	0	1149	7161
hsa_M00014	Glucuronate pathway (uronate pathway)	1.00000000003112	3.11181321736524e-11	27	0	0	1149	7161
M00014	Glucuronate pathway (uronate pathway)	1.00000000003112	3.11181321736524e-11	27	0	0	1149	7161
hsa00591	Linoleic acid metabolism	1.00000000003451	3.45104360248446e-11	29	0	0	1149	7161
ko00591	Linoleic acid metabolism	1.00000000003451	3.45104360248446e-11	29	0	0	1149	7161
ko05033	Nicotine addiction	1.00000000003811	3.8109142448266e-11	40	0	0	1149	7161
hsa05033	Nicotine addiction	1.00000000003811	3.8109142448266e-11	40	0	0	1149	7161
ko00140	Steroid hormone biosynthesis	1.00000000004875	4.87500219175647e-11	58	0	0	1149	7161
hsa00140	Steroid hormone biosynthesis	1.00000000004875	4.87500219175647e-11	58	0	0	1149	7161