TermID	Term	Enrichment	logP	Genes in Term	Target Genes in Term	Fraction of Targets in Term	Total Target Genes	Total Genes	Entrez Gene IDs	Gene Symbols
mtor_4pathway	mTOR signaling pathway	0.000119176421954197	-9.03490562529618	60	24	0.0563380281690141	426	2226	5170,387,7249,9821,5894,6195,5879,54205,84335,5605,6009,5595,29904,7248,54700,5371,9776,7534,7528,7533,5594,1017,27250,64223	PDPK1,RHOA,TSC2,RB1CC1,RAF1,RPS6KA1,RAC1,CYCS,AKT1S1,MAP2K2,RHEB,MAPK3,EEF2K,TSC1,RRN3,PML,ATG13,YWHAZ,YY1,YWHAH,MAPK1,CDK2,PDCD4,MLST8
e2f_pathway	E2F transcription factor network	0.000441334028809196	-7.72570853428502	72	26	0.0610328638497653	426	2226	7083,2648,4605,6240,1871,6241,4170,990,672,4998,10155,1031,5925,890,5933,7030,1874,7027,1869,1027,5928,7528,7029,1017,1870,23429	TK1,KAT2A,MYBL2,RRM1,E2F3,RRM2,MCL1,CDC6,BRCA1,ORC1,TRIM28,CDKN2C,RB1,CCNA2,RBL1,TFE3,E2F4,TFDP1,E2F1,CDKN1B,RBBP4,YY1,TFDP2,CDK2,E2F2,RYBP
aurora_b_pathway	Aurora B signaling	0.00362755722025096	-5.61919579931216	39	15	0.0352112676056338	426	2226	387,1731,332,6867,54888,55143,8452,9493,29127,11004,10592,9212,64151,3925,10051	RHOA,SEPT1,BIRC5,TACC1,NSUN2,CDCA8,CUL3,KIF23,RACGAP1,KIF2C,SMC2,AURKB,NCAPG,STMN1,SMC4
smad2_3pathway	Regulation of cytoplasmic and nuclear SMAD2/3 signaling	0.00472578328605392	-5.35472195694933	19	9	0.0211267605633803	426	2226	805,4087,9972,3838,7329,5594,10106,4089,5595	CALM2,SMAD2,NUP153,KPNA2,UBE2I,MAPK1,CTDSP2,SMAD4,MAPK3
plk1_pathway	PLK1 signaling events	0.0051648503698805	-5.26587914684363	44	16	0.0375586854460094	426	2226	3796,5515,5347,387,2801,4659,63967,64689,22974,994,891,5861,79866,79682,10726,26271	KIF2A,PPP2CA,PLK1,RHOA,GOLGA2,PPP1R12A,CLSPN,GORASP1,TPX2,CDC25B,CCNB1,RAB1A,BORA,CENPU,NUDC,FBXO5
prlsignalingeventspathway	Signaling events mediated by PRL	0.00622224415740338	-5.07962464029245	23	10	0.0234741784037559	426	2226	387,890,389,5879,3688,11156,6093,1017,5594,5595	RHOA,CCNA2,RHOC,RAC1,ITGB1,PTP4A3,ROCK1,CDK2,MAPK1,MAPK3
p38_mk2pathway	p38 signaling mediated by MAPKAP kinases	0.00716659075551327	-4.93832522482669	20	9	0.0211267605633803	426	2226	7249,7867,5894,6929,7534,994,1385,7533,1432	TSC2,MAPKAPK3,RAF1,TCF3,YWHAZ,CDC25B,CREB1,YWHAH,MAPK14
wnt_canonical_pathway	Canonical Wnt signaling pathway	0.00851049249732989	-4.7664554652947	31	12	0.028169014084507	426	2226	5515,53944,8312,8313,8452,85409,8454,1855,1452,1453,1856,55361	PPP2CA,CSNK1G1,AXIN1,AXIN2,CUL3,NKD2,CUL1,DVL1,CSNK1A1,CSNK1D,DVL2,PI4K2A
p53regulationpathway	p53 pathway	0.0107676989329417	-4.53120446589284	59	19	0.0446009389671361	426	2226	7874,1455,1452,1432,10155,6135,5515,4193,890,10075,387893,53944,5300,28996,11200,7528,1017,1456,1453	USP7,CSNK1G2,CSNK1A1,MAPK14,TRIM28,RPL11,PPP2CA,MDM2,CCNA2,HUWE1,KMT5A,CSNK1G1,PIN1,HIPK2,CHEK2,YY1,CDK2,CSNK1G3,CSNK1D
rb_1pathway	Regulation of retinoblastoma protein	0.0131794521192601	-4.32909631987194	56	18	0.0422535211267606	426	2226	26574,5894,6597,1432,7343,5515,5925,4193,890,6046,1874,7027,1027,5928,1386,1017,1786,8535	AATF,RAF1,SMARCA4,MAPK14,UBTF,PPP2CA,RB1,MDM2,CCNA2,BRD2,E2F4,TFDP1,CDKN1B,RBBP4,ATF2,CDK2,DNMT1,CBX4
myc_activpathway	Validated targets of C-MYC transcriptional activation	0.0136107756860383	-4.29689347011197	81	24	0.0563380281690141	426	2226	7083,4149,2648,91942,6513,3939,1871,84864,891,9913,4953,7037,6135,7343,100532731,3308,11235,332,10935,10075,9112,6883,10856,4089	TK1,MAX,KAT2A,NDUFAF2,SLC2A1,LDHA,E2F3,RIOX2,CCNB1,SUPT7L,ODC1,TFRC,RPL11,UBTF,COMMD3-BMI1,HSPA4,PDCD10,BIRC5,PRDX3,HUWE1,MTA1,TAF12,RUVBL2,SMAD4
p38_mkk3_6pathway	p38 MAPK signaling pathway	0.0137631068622173	-4.2857636825582	29	11	0.0258215962441315	426	2226	4216,805,7295,23118,83605,4616,57551,5879,10912,4217,1432	MAP3K4,CALM2,TXN,TAB2,CCM2,GADD45B,TAOK1,RAC1,GADD45G,MAP3K5,MAPK14
myc_pathway	C-MYC pathway	0.0147870022798506	-4.21400670841141	22	9	0.0211267605633803	426	2226	5515,4149,2648,5525,5300,8312,6883,10856,9913	PPP2CA,MAX,KAT2A,PPP2R5A,PIN1,AXIN1,TAF12,RUVBL2,SUPT7L
bcr_5pathway	BCR signaling pathway	0.0182195115229562	-4.00526219744626	66	20	0.0469483568075117	426	2226	5170,5530,5894,5879,7410,1457,5532,2002,2113,4067,1432,5595,9467,805,6464,1445,5728,5594,3265,818	PDPK1,PPP3CA,RAF1,RAC1,VAV2,CSNK2A1,PPP3CB,ELK1,ETS1,LYN,MAPK14,MAPK3,SH3BP5,CALM2,SHC1,CSK,PTEN,MAPK1,HRAS,CAMK2G
pi3kciaktpathway	Class I PI3K signaling events mediated by Akt	0.0190195849363657	-3.96228604458641	34	12	0.028169014084507	426	2226	5170,3836,5591,5894,208,1027,7534,4217,7533,5566,2309,64223	PDPK1,KPNA1,PRKDC,RAF1,AKT2,CDKN1B,YWHAZ,MAP3K5,YWHAH,PRKACA,FOXO3,MLST8
lkb1_pathway	LKB1 signaling events	0.0198560371699495	-3.91924717854594	42	14	0.0328638497652582	426	2226	7248,7249,7430,51719,6794,7534,84335,1385,7533,5566,2011,4089,64223,11140	TSC1,TSC2,EZR,CAB39,STK11,YWHAZ,AKT1S1,CREB1,YWHAH,PRKACA,MARK2,SMAD4,MLST8,CDC37
erbb1_downstream_pathway	ErbB1 downstream signaling	0.0231651239709776	-3.76510740847761	102	28	0.0657276995305164	426	2226	5170,10163,5894,5879,10096,7410,10787,2002,26999,5605,378,5595,824,5515,805,998,10092,6772,7534,1385,5536,4086,7533,6774,5594,1386,10006,64223	PDPK1,WASF2,RAF1,RAC1,ACTR3,VAV2,NCKAP1,ELK1,CYFIP2,MAP2K2,ARF4,MAPK3,CAPN2,PPP2CA,CALM2,CDC42,ARPC5,STAT1,YWHAZ,CREB1,PPP5C,SMAD1,YWHAH,STAT3,MAPK1,ATF2,ABI1,MLST8
nfat_3pathway	Role of Calcineurin-dependent NFAT signaling in lymphocytes	0.0239146713939798	-3.73326314252635	51	16	0.0375586854460094	426	2226	1457,4773,4209,1452,5566,1432,5595,805,2280,4775,23523,596,3838,7534,7533,11261	CSNK2A1,NFATC2,MEF2D,CSNK1A1,PRKACA,MAPK14,MAPK3,CALM2,FKBP1A,NFATC3,CABIN1,BCL2,KPNA2,YWHAZ,YWHAH,CHP1
s1p_s1p2_pathway	S1P2 pathway	0.0271372824103988	-3.60684676185137	24	9	0.0211267605633803	426	2226	2768,387,2002,9294,5594,2771,1432,5879,5595	GNA12,RHOA,ELK1,S1PR2,MAPK1,GNAI2,MAPK14,RAC1,MAPK3
foxopathway	FoxO family signaling	0.0293150882144032	-3.52965293938054	48	15	0.0352112676056338	426	2226	7874,847,5347,1455,53944,1027,7534,891,7533,1452,7763,1017,2309,1453,1456	USP7,CAT,PLK1,CSNK1G2,CSNK1G1,CDKN1B,YWHAZ,CCNB1,YWHAH,CSNK1A1,ZFAND5,CDK2,FOXO3,CSNK1D,CSNK1G3
s1p_s1p4_pathway	S1P4 pathway	0.0355636753136267	-3.33643051840088	14	6	0.0140845070422535	426	2226	2768,387,998,5594,2771,5595	GNA12,RHOA,CDC42,MAPK1,GNAI2,MAPK3
hdac_classi_pathway	Signaling events mediated by HDAC Class I	0.0356254105524502	-3.33469611618042	66	19	0.0446009389671361	426	2226	9612,4149,9219,5905,22933,7329,53615,5566,2287,4084,1107,51564,8932,7528,5928,6774,57154,3066,8819	NCOR2,MAX,MTA2,RANGAP1,SIRT2,UBE2I,MBD3,PRKACA,FKBP3,MXD1,CHD3,HDAC7,MBD2,YY1,RBBP4,STAT3,SMURF1,HDAC2,SAP30
telomerasepathway	Regulation of Telomerase	0.0356254105524502	-3.33469611618042	66	19	0.0446009389671361	426	2226	7040,6670,4149,641,4084,5595,7520,54386,1869,1027,10728,7026,5928,5594,7013,25913,3066,7014,8819	TGFB1,SP3,MAX,BLM,MXD1,MAPK3,XRCC5,TERF2IP,E2F1,CDKN1B,PTGES3,NR2F2,RBBP4,MAPK1,TERF1,POT1,HDAC2,TERF2,SAP30
bard1pathway	BARD1 signaling events	0.0366536024695241	-3.30624356163214	29	10	0.0234741784037559	426	2226	7323,55120,2130,5111,5591,672,2178,1017,7520,1477	UBE2D3,FANCL,EWSR1,PCNA,PRKDC,BRCA1,FANCE,CDK2,XRCC5,CSTF1
mapktrkpathway	Trk receptor signaling mediated by the MAPK pathway	0.0366536024695241	-3.30624356163214	29	10	0.0234741784037559	426	2226	1020,5894,6195,6016,1385,2002,30844,1432,5594,5595	CDK5,RAF1,RPS6KA1,RIT1,CREB1,ELK1,EHD4,MAPK14,MAPK1,MAPK3
foxm1pathway	FOXM1 transcription factor network	0.0370807574213502	-3.2946571118116	37	12	0.028169014084507	426	2226	5347,5925,4775,332,2305,1063,994,9212,11200,891,1017,9133	PLK1,RB1,NFATC3,BIRC5,FOXM1,CENPF,CDC25B,AURKB,CHEK2,CCNB1,CDK2,CCNB2
ecadherin_nascentaj_pathway	E-cadherin signaling in the nascent adherens junction	0.0371267387626078	-3.29341784759957	33	11	0.0258215962441315	426	2226	10163,387,27252,998,5879,7410,8907,10787,26999,10006,23396	WASF2,RHOA,KLHL20,CDC42,RAC1,VAV2,AP1M1,NCKAP1,CYFIP2,ABI1,PIP5K1C
epopathway	EPO signaling pathway	0.0371267387626078	-3.29341784759957	33	11	0.0258215962441315	426	2226	1399,5906,6464,7410,5781,6772,596,598,1432,4067,3265	CRKL,RAP1A,SHC1,VAV2,PTPN11,STAT1,BCL2,BCL2L1,MAPK14,LYN,HRAS
syndecan_2_pathway	Syndecan-2-mediated signaling events	0.0371267387626078	-3.29341784759957	33	11	0.0258215962441315	426	2226	7040,387,4763,6383,3688,7430,5566,5594,3265,5595,2035	TGFB1,RHOA,NF1,SDC2,ITGB1,EZR,PRKACA,MAPK1,HRAS,MAPK3,EPB41
ncadherinpathway	N-cadherin signaling events	0.0371267387626078	-3.29341784759957	33	11	0.0258215962441315	426	2226	3799,805,387,22919,8312,5879,4041,6093,818,1639,23396	KIF5B,CALM2,RHOA,MAPRE1,AXIN1,RAC1,LRP5,ROCK1,CAMK2G,DCTN1,PIP5K1C
tcrraspathway	Ras signaling in the CD4+ TCR pathway	0.0420916240992205	-3.16790651060006	11	5	0.0117370892018779	426	2226	2002,5594,5894,5595,5778	ELK1,MAPK1,RAF1,MAPK3,PTPN7
smad2_3nuclearpathway	Regulation of nuclear SMAD2/3 signaling	0.0428894265649463	-3.14912995044372	76	21	0.0492957746478873	426	2226	4149,2648,6929,865,3693,2309,4087,5933,7030,7027,51586,55802,8648,5928,1385,1017,1386,4089,10499,3066,8819	MAX,KAT2A,TCF3,CBFB,ITGB5,FOXO3,SMAD2,RBL1,TFE3,TFDP1,MED15,DCP1A,NCOA1,RBBP4,CREB1,CDK2,ATF2,SMAD4,NCOA2,HDAC2,SAP30
wnt_noncanonical_pathway	Noncanonical Wnt signaling pathway	0.0459317027601884	-3.08059970839044	30	10	0.0234741784037559	426	2226	387,998,23118,5879,4773,6093,1855,1452,409,1856	RHOA,CDC42,TAB2,RAC1,NFATC2,ROCK1,DVL1,CSNK1A1,ARRB2,DVL2
tgfbrpathway	TGF-beta receptor signaling	0.0490419409672123	-3.01507940887126	51	15	0.0352112676056338	426	2226	5170,7040,5515,2280,387,4087,6464,8312,5371,331,83939,57154,409,4089,11171	PDPK1,TGFB1,PPP2CA,FKBP1A,RHOA,SMAD2,SHC1,AXIN1,PML,XIAP,EIF2A,SMURF1,ARRB2,SMAD4,STRAP
arf6downstreampathway	Arf6 downstream pathway	0.0499838041126235	-2.99605624377421	15	6	0.0140845070422535	426	2226	387,375,5594,8766,5879,5595	RHOA,ARF1,MAPK1,RAB11A,RAC1,MAPK3
aurora_a_pathway	Aurora A signaling	0.0566752745249975	-2.87041723875383	31	10	0.0234741784037559	426	2226	4193,332,6867,22974,994,9212,672,5566,4946,10460	MDM2,BIRC5,TACC1,TPX2,CDC25B,AURKB,BRCA1,PRKACA,OAZ1,TACC3
kitpathway	Signaling events mediated by Stem cell factor receptor (c-Kit)	0.0573037310004697	-2.85938954393499	52	15	0.0352112676056338	426	2226	5170,1399,7409,6464,5728,5894,5781,6772,596,6774,4067,3265,5605,2309,5595	PDPK1,CRKL,VAV1,SHC1,PTEN,RAF1,PTPN11,STAT1,BCL2,STAT3,LYN,HRAS,MAP2K2,FOXO3,MAPK3
myc_represspathway	Validated targets of C-MYC transcriptional repression	0.0601562692542481	-2.81080961498941	61	17	0.039906103286385	426	2226	7812,1788,4149,7249,5933,3688,1027,596,10608,672,1191,1385,2966,2309,4089,8837,223	CSDE1,DNMT3A,MAX,TSC2,RBL1,ITGB1,CDKN1B,BCL2,MXD4,BRCA1,CLU,CREB1,GTF2H2,FOXO3,SMAD4,CFLAR,ALDH9A1
rhoa_reg_pathway	Regulation of RhoA activity	0.0849377361508446	-2.46583680678508	46	13	0.0305164319248826	426	2226	7409,387,10276,9138,7204,7410,116985,9181,1027,23365,397,4650,50619	VAV1,RHOA,NET1,ARHGEF1,TRIO,VAV2,ARAP1,ARHGEF2,CDKN1B,ARHGEF12,ARHGDIB,MYO9B,DEF6
ret_pathway	Signaling events regulated by Ret tyrosine kinase	0.0937513284708584	-2.36710944387619	38	11	0.0258215962441315	426	2226	387,5906,6464,4690,5879,5781,1385,5566,5594,3265,5595	RHOA,RAP1A,SHC1,NCK1,RAC1,PTPN11,CREB1,PRKACA,MAPK1,HRAS,MAPK3
pi3kcibpathway	Class IB PI3K non-lipid kinase events	0.0957260055847944	-2.34626527674009	3	2	0.00469483568075117	426	2226	5140,5594	PDE3B,MAPK1
il2_1pathway	IL2-mediated signaling events	0.10568185204484	-2.24732209389476	52	14	0.0328638497652582	426	2226	387,3716,6464,5894,5781,6772,596,6774,5594,1432,1017,5605,8027,5595	RHOA,JAK1,SHC1,RAF1,PTPN11,STAT1,BCL2,STAT3,MAPK1,MAPK14,CDK2,MAP2K2,STAM,MAPK3
rxr_vdr_pathway	RXR and RAR heterodimerization with other nuclear receptor	0.11132929266041	-2.19526286880154	14	5	0.0117370892018779	426	2226	7040,9612,596,8648,19	TGFB1,NCOR2,BCL2,NCOA1,ABCA1
ar_nongenomic_pathway	Nongenotropic Androgen signaling	0.111830356592457	-2.19077222924591	18	6	0.0140845070422535	426	2226	1385,5594,3265,5894,5605,5595	CREB1,MAPK1,HRAS,RAF1,MAP2K2,MAPK3
arf_3pathway	Arf1 pathway	0.111830356592457	-2.19077222924591	18	6	0.0140845070422535	426	2226	23647,375,8615,1212,1314,5879	ARFIP2,ARF1,USO1,CLTB,COPA,RAC1
tnfpathway	TNF receptor signaling pathway	0.118873567724446	-2.12969480677427	44	12	0.028169014084507	426	2226	6868,1540,7295,7128,330,9448,6772,117584,8491,4217,329,8772	ADAM17,CYLD,TXN,TNFAIP3,BIRC3,MAP4K4,STAT1,RFFL,MAP4K3,MAP3K5,BIRC2,FADD
ceramide_pathway	Ceramide signaling pathway	0.118873567724446	-2.12969480677427	44	12	0.028169014084507	426	2226	330,5894,9448,427,54205,596,5074,8575,5594,5605,8772,5595	BIRC3,RAF1,MAP4K4,ASAH1,CYCS,BCL2,PAWR,PRKRA,MAPK1,MAP2K2,FADD,MAPK3
met_pathway	Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)	0.129819652670198	-2.0416090788526	72	18	0.0422535211267606	426	2226	5170,387,4690,208,5894,5879,84335,2113,5605,5595,1399,9146,998,5781,5594,3265,8650,64223	PDPK1,RHOA,NCK1,AKT2,RAF1,RAC1,AKT1S1,ETS1,MAP2K2,MAPK3,CRKL,HGS,CDC42,PTPN11,MAPK1,HRAS,NUMB,MLST8
rac1_pathway	RAC1 signaling pathway	0.134871010467929	-2.00343643531914	54	14	0.0328638497652582	426	2226	10163,10092,3984,5879,10096,29127,10787,26999,6774,1386,1432,10006,1072,23396	WASF2,ARPC5,LIMK1,RAC1,ACTR3,RACGAP1,NCKAP1,CYFIP2,STAT3,ATF2,MAPK14,ABI1,CFL1,PIP5K1C
ranbp2pathway	Sumoylation by RanBP2 regulates transcriptional repression	0.142051117899837	-1.95156830094989	11	4	0.00938967136150235	426	2226	5905,4193,7329,9063	RANGAP1,MDM2,UBE2I,PIAS2
rhoa_pathway	RhoA signaling pathway	0.144284852594445	-1.93596579033769	41	11	0.0258215962441315	426	2226	387,4659,998,5728,3984,7430,1027,6093,1386,1072,23396	RHOA,PPP1R12A,CDC42,PTEN,LIMK1,EZR,CDKN1B,ROCK1,ATF2,CFL1,PIP5K1C
pi3kcipathway	Class I PI3K signaling events	0.144284852594445	-1.93596579033769	41	11	0.0258215962441315	426	2226	5170,7409,9267,387,5906,5728,381,5879,375,4067,2309	PDPK1,VAV1,CYTH1,RHOA,RAP1A,PTEN,ARF5,RAC1,ARF1,LYN,FOXO3
il2_pi3kpathway	IL2 signaling events mediated by PI3K	0.153703211341958	-1.87273173508423	37	10	0.0234741784037559	426	2226	805,3716,6464,5879,1869,5781,596,598,2309,8661	CALM2,JAK1,SHC1,RAC1,E2F1,PTPN11,BCL2,BCL2L1,FOXO3,EIF3A
alk1pathway	ALK1 signaling events	0.15882208435032	-1.83997066962235	24	7	0.0164319248826291	426	2226	7040,2280,4086,5594,409,4089,5595	TGFB1,FKBP1A,SMAD1,MAPK1,ARRB2,SMAD4,MAPK3
p53downstreampathway	Direct p53 effectors	0.166322405844729	-1.7938271703811	132	30	0.0704225352112676	426	2226	578,1263,5564,7249,839,7832,9448,5395,6890,6597,4170,891,3663,133746,355,8812,5925,4193,5111,57103,5728,54487,7027,5371,4436,1655,596,7159,3066,10498	BAK1,PLK3,PRKAB1,TSC2,CASP6,BTG2,MAP4K4,PMS2,TAP1,SMARCA4,MCL1,CCNB1,IRF5,JMY,FAS,CCNK,RB1,MDM2,PCNA,TIGAR,PTEN,DGCR8,TFDP1,PML,MSH2,DDX5,BCL2,TP53BP2,HDAC2,CARM1
plk_pathway	Polo-like kinase signaling events in the cell cycle	0.167554048161784	-1.78644930417285	4	2	0.00469483568075117	426	2226	1263,5347	PLK3,PLK1
s1p_s1p1_pathway	S1P1 pathway	0.167564522139918	-1.78638679508463	20	6	0.0140845070422535	426	2226	387,2771,5594,5879,5595,4363	RHOA,GNAI2,MAPK1,RAC1,MAPK3,ABCC1
trkrpathway	Neurotrophic factor-mediated Trk receptor signaling	0.168115304495235	-1.78310519871875	56	14	0.0328638497652582	426	2226	1399,391,387,6464,998,9844,5879,9500,5781,6016,30844,6774,5594,5595	CRKL,RHOG,RHOA,SHC1,CDC42,ELMO1,RAC1,MAGED1,PTPN11,RIT1,EHD4,STAT3,MAPK1,MAPK3
s1p_s1p5_pathway	S1P5 pathway	0.184090070278853	-1.69233012876018	8	3	0.00704225352112676	426	2226	2768,387,2771	GNA12,RHOA,GNAI2
retinoic_acid_pathway	Retinoic acid receptors-mediated signaling	0.186483077209968	-1.67941478283583	25	7	0.0164319248826291	426	2226	9612,8648,5594,5566,1432,10499,5595	NCOR2,NCOA1,MAPK1,PRKACA,MAPK14,NCOA2,MAPK3
rac1_reg_pathway	Regulation of RAC1 activity	0.197836610587809	-1.62031378800323	39	10	0.0234741784037559	426	2226	7409,55114,9844,5879,7204,7410,9181,29127,10006,50619	VAV1,ARHGAP17,ELMO1,RAC1,TRIO,VAV2,ARHGEF2,RACGAP1,ABI1,DEF6
hedgehog_glipathway	Hedgehog signaling events mediated by Gli proteins	0.206417211741018	-1.57785585863339	44	11	0.0258215962441315	426	2226	1455,53944,51715,5928,5566,409,1452,3066,1453,1456,8819	CSNK1G2,CSNK1G1,RAB23,RBBP4,PRKACA,ARRB2,CSNK1A1,HDAC2,CSNK1D,CSNK1G3,SAP30
syndecan_1_pathway	Syndecan-1-mediated signaling events	0.212412993081655	-1.5492228187845	17	5	0.0117370892018779	426	2226	7040,5479,5594,5566,5595	TGFB1,PPIB,MAPK1,PRKACA,MAPK3
erbb2erbb3pathway	ErbB2/ErbB3 signaling events	0.21249482625995	-1.54883763792606	35	9	0.0211267605633803	426	2226	6464,5894,5781,5532,5566,5594,6774,5605,5595	SHC1,RAF1,PTPN11,PPP3CB,PRKACA,MAPK1,STAT3,MAP2K2,MAPK3
hivnefpathway	HIV-1 Nef: Negative effector of Fas and TNF-alpha	0.21249482625995	-1.54883763792606	35	9	0.0211267605633803	426	2226	330,839,54205,596,4217,9020,8772,8837,355	BIRC3,CASP6,CYCS,BCL2,MAP3K5,MAP3K14,FADD,CFLAR,FAS
pdgfrbpathway	PDGFR-beta signaling pathway	0.219700492842391	-1.51549005634242	54	13	0.0305164319248826	426	2226	6464,5728,1445,4690,5879,7410,29907,5781,6772,1785,6774,4067,3265	SHC1,PTEN,CSK,NCK1,RAC1,VAV2,SNX15,PTPN11,STAT1,DNM2,STAT3,LYN,HRAS
ifngpathway	IFN-gamma pathway	0.221756541722457	-1.50617515778809	40	10	0.0234741784037559	426	2226	1399,805,3716,5781,6772,1612,5594,6774,818,5595	CRKL,CALM2,JAK1,PTPN11,STAT1,DAPK1,MAPK1,STAT3,CAMK2G,MAPK3
ecadherin_stabilization_pathway	Stabilization and expansion of the E-cadherin adherens junction	0.221756541722457	-1.50617515778809	40	10	0.0234741784037559	426	2226	11336,387,7408,4690,60412,6093,10787,26999,10006,23396	EXOC3,RHOA,VASP,NCK1,EXOC4,ROCK1,NCKAP1,CYFIP2,ABI1,PIP5K1C
lis1pathway	Lissencephaly gene (LIS1) in neuronal migration and development	0.228757015842034	-1.47509490494914	31	8	0.0187793427230047	426	2226	805,1020,1457,387,998,7804,5879,10726	CALM2,CDK5,CSNK2A1,RHOA,CDC42,LRP8,RAC1,NUDC
txa2pathway	Thromboxane A2 receptor signaling	0.229353344386436	-1.47249147602462	45	11	0.0258215962441315	426	2226	387,156,9138,5879,6093,1432,409,2771,5566,4067,8766	RHOA,GRK2,ARHGEF1,RAC1,ROCK1,MAPK14,ARRB2,GNAI2,PRKACA,LYN,RAB11A
caspase_pathway	Caspase cascade in apoptosis	0.235665660364875	-1.44534117178454	50	12	0.028169014084507	426	2226	330,839,3984,331,397,54205,596,2620,329,351,4000,6709	BIRC3,CASP6,LIMK1,XIAP,ARHGDIB,CYCS,BCL2,GAS2,BIRC2,APP,LMNA,SPTAN1
atf2_pathway	ATF-2 transcription factor network	0.240964587526503	-1.42310529601223	55	13	0.0305164319248826	426	2226	890,4763,8452,9555,596,672,10856,1385,5594,1432,865,1386,5595	CCNA2,NF1,CUL3,H2AFY,BCL2,BRCA1,RUVBL2,CREB1,MAPK1,MAPK14,CBFB,ATF2,MAPK3
plk3_pathway	PLK3 signaling events	0.24504989007704	-1.40629345620028	5	2	0.00469483568075117	426	2226	1263,11200	PLK3,CHEK2
ps1pathway	Presenilin action in Notch and Wnt signaling	0.253231440428954	-1.37345142411062	46	11	0.0258215962441315	426	2226	51107,102,8312,1457,3516,1855,1452,5594,83464,5663,5595	APH1A,ADAM10,AXIN1,CSNK2A1,RBPJ,DVL1,CSNK1A1,MAPK1,APH1B,PSEN1,MAPK3
p75ntrpathway	p75(NTR)-mediated signaling	0.266690505363447	-1.3216664488649	61	14	0.0328638497652582	426	2226	387,6868,28986,6464,839,51107,11108,5879,9500,1869,54205,83464,5663,351	RHOA,ADAM17,MAGEH1,SHC1,CASP6,APH1A,PRDM4,RAC1,MAGED1,E2F1,CYCS,APH1B,PSEN1,APP
lymphangiogenesis_pathway	VEGFR3 signaling in lymphatic endothelium	0.267589059842638	-1.31830283406513	23	6	0.0140845070422535	426	2226	1385,5594,1432,6195,5595,3688	CREB1,MAPK1,MAPK14,RPS6KA1,MAPK3,ITGB1
cxcr4_pathway	CXCR4-mediated signaling events	0.274648768037132	-1.29226220477746	76	17	0.039906103286385	426	2226	5170,4067,5996,7409,9146,156,5899,1445,3984,6772,3688,5781,27183,409,6774,1072,64223	PDPK1,LYN,RGS1,VAV1,HGS,GRK2,RALB,CSK,LIMK1,STAT1,ITGB1,PTPN11,VPS4A,ARRB2,STAT3,CFL1,MLST8
s1p_s1p3_pathway	S1P3 pathway	0.279237194676819	-1.27569369821024	28	7	0.0164319248826291	426	2226	2768,387,9294,5594,2771,5879,5595	GNA12,RHOA,S1PR2,MAPK1,GNAI2,RAC1,MAPK3
igf1_pathway	IGF1 pathway	0.279237194676819	-1.27569369821024	28	7	0.0164319248826291	426	2226	5170,1399,7534,6464,3265,5894,5781	PDPK1,CRKL,YWHAZ,SHC1,HRAS,RAF1,PTPN11
tcrcalciumpathway	Calcium signaling in the CD4+ TCR pathway	0.279237194676819	-1.27569369821024	28	7	0.0164319248826291	426	2226	2280,805,4773,23523,4775,5566,11261	FKBP1A,CALM2,NFATC2,CABIN1,NFATC3,PRKACA,CHP1
ar_pathway	Coregulation of Androgen receptor activity	0.285684697082923	-1.25286653406787	57	13	0.0305164319248826	426	2226	5036,5591,5074,672,57178,7329,55818,26060,10106,5052,10499,10498,7520	PA2G4,PRKDC,PAWR,BRCA1,ZMIZ1,UBE2I,KDM3A,APPL1,CTDSP2,PRDX1,NCOA2,CARM1,XRCC5
ephbfwdpathway	EPHB forward signaling	0.287822795761393	-1.24541028071146	33	8	0.0187793427230047	426	2226	6093,998,5594,4690,3265,9448,5879,5595	ROCK1,CDC42,MAPK1,NCK1,HRAS,MAP4K4,RAC1,MAPK3
insulin_pathway	Insulin Pathway	0.299379723144846	-1.20604253425716	43	10	0.0234741784037559	426	2226	5170,11336,6464,9322,4690,208,5781,60412,3265,2309	PDPK1,EXOC3,SHC1,TRIP10,NCK1,AKT2,PTPN11,EXOC4,HRAS,FOXO3
endothelinpathway	Endothelins	0.306468956497045	-1.18263881259499	53	12	0.028169014084507	426	2226	2768,387,998,5894,115,5879,1432,5594,3265,5605,5595,113	GNA12,RHOA,CDC42,RAF1,ADCY9,RAC1,MAPK14,MAPK1,HRAS,MAP2K2,MAPK3,ADCY7
vegfr1_2_pathway	Signaling events mediated by VEGFR1 and VEGFR2	0.310938907611888	-1.16815882464647	63	14	0.0328638497652582	426	2226	5170,805,387,6464,998,4690,7428,5879,5781,6093,5594,5566,3265,5595	PDPK1,CALM2,RHOA,SHC1,CDC42,NCK1,VHL,RAC1,PTPN11,ROCK1,MAPK1,PRKACA,HRAS,MAPK3
vegfr1_pathway	VEGFR1 specific signals	0.312483950458578	-1.16320216965713	29	7	0.0164319248826291	426	2226	5170,805,5594,4690,5566,5595,5781	PDPK1,CALM2,MAPK1,NCK1,PRKACA,MAPK3,PTPN11
cmyb_pathway	C-MYB transcription factor network	0.314689727281012	-1.15616811833935	78	17	0.039906103286385	426	2226	5530,4893,3015,330,2114,1314,839,28996,1027,596,27044,7329,891,2113,10155,8535,4144	PPP3CA,NRAS,H2AFZ,BIRC3,ETS2,COPA,CASP6,HIPK2,CDKN1B,BCL2,SND1,UBE2I,CCNB1,ETS1,TRIM28,CBX4,MAT2A
cxcr3pathway	CXCR3-mediated signaling events	0.318700572133474	-1.14350326235031	34	8	0.0187793427230047	426	2226	5170,5894,1432,2771,5594,5605,64223,5595	PDPK1,RAF1,MAPK14,GNAI2,MAPK1,MAP2K2,MLST8,MAPK3
lpa4_pathway	LPA4-mediated signaling events	0.319417630160587	-1.14125584697695	15	4	0.00938967136150235	426	2226	1385,5566,115,113	CREB1,PRKACA,ADCY9,ADCY7
arf6_traffickingpathway	Arf6 trafficking events	0.326721638264522	-1.11864672974159	44	10	0.0234741784037559	426	2226	11336,966,8853,60412,9744,3688,1785,3831,154,23396	EXOC3,CD59,ASAP2,EXOC4,ACAP1,ITGB1,DNM2,KLC1,ADRB2,PIP5K1C
erbb1_receptor_proximal_pathway	EGF receptor (ErbB1) signaling pathway	0.340906289223152	-1.07614765112857	25	6	0.0140845070422535	426	2226	6774,5594,5595,5781,23396,6772	STAT3,MAPK1,MAPK3,PTPN11,PIP5K1C,STAT1
faspathway	FAS (CD95) signaling pathway	0.350168941280786	-1.04933955158205	35	8	0.0187793427230047	426	2226	5170,7430,330,1432,329,8772,355,8837	PDPK1,EZR,BIRC3,MAPK14,BIRC2,FADD,FAS,CFLAR
p38alphabetadownstreampathway	Signaling mediated by p38-alpha and p38-beta	0.350168941280786	-1.04933955158205	35	8	0.0187793427230047	426	2226	22926,4205,8569,7391,1385,1386,7867,1432	ATF6,MEF2A,MKNK1,USF1,CREB1,ATF2,MAPKAPK3,MAPK14
alk2pathway	ALK2 signaling events	0.353903803932856	-1.03873014307912	11	3	0.00704225352112676	426	2226	2280,4086,4089	FKBP1A,SMAD1,SMAD4
hif1_tfpathway	HIF-1-alpha transcription factor network	0.356976413121151	-1.03008556907385	65	14	0.0328638497652582	426	2226	51564,6513,3939,5209,4170,8648,1385,10370,5315,2113,4089,10499,7037,54583	HDAC7,SLC2A1,LDHA,PFKFB3,MCL1,NCOA1,CREB1,CITED2,PKM,ETS1,SMAD4,NCOA2,TFRC,EGLN1
il27pathway	IL27-mediated signaling events	0.378393032601994	-0.97182185475936	26	6	0.0140845070422535	426	2226	7040,3594,3716,6774,3572,6772	TGFB1,IL12RB1,JAK1,STAT3,IL6ST,STAT1
tcptp_pathway	Signaling events mediated by TCPTP	0.381999965070897	-0.962334761813009	36	8	0.0187793427230047	426	2226	3838,3716,3998,6774,6778,5867,6772,3688	KPNA2,JAK1,LMAN1,STAT3,STAT6,RAB4A,STAT1,ITGB1
reg_gr_pathway	Glucocorticoid receptor regulatory network	0.398750489535382	-0.919419397208898	82	17	0.039906103286385	426	2226	6613,6597,1432,5566,5595,1020,4193,6772,2289,8648,5536,1385,7533,5594,3066,10499,6602	SUMO2,SMARCA4,MAPK14,PRKACA,MAPK3,CDK5,MDM2,STAT1,FKBP5,NCOA1,PPP5C,CREB1,YWHAH,MAPK1,HDAC2,NCOA2,SMARCD1
pdgfrapathway	PDGFR-alpha signaling pathway	0.416063900494569	-0.876916423559117	22	5	0.0117370892018779	426	2226	1399,1457,3716,6464,2002	CRKL,CSNK2A1,JAK1,SHC1,ELK1
notch_pathway	Notch signaling pathway	0.433359308828557	-0.83618808254664	58	12	0.028169014084507	426	2226	9612,51107,102,8454,3516,4853,9794,7528,83464,2011,8766,8650	NCOR2,APH1A,ADAM10,CUL1,RBPJ,NOTCH2,MAML1,YY1,APH1B,MARK2,RAB11A,NUMB
angiopoietinreceptor_pathway	Angiopoietin receptor Tie2-mediated signaling	0.43932380880678	-0.822518532321781	48	10	0.0234741784037559	426	2226	6464,4690,5879,5781,3688,2002,1432,5594,2113,5595	SHC1,NCK1,RAC1,PTPN11,ITGB1,ELK1,MAPK14,MAPK1,ETS1,MAPK3
hes_heypathway	Notch-mediated HES/HEY network	0.43932380880678	-0.822518532321781	48	10	0.0234741784037559	426	2226	9612,5925,6929,1869,1027,8648,3516,9794,7528,6774	NCOR2,RB1,TCF3,E2F1,CDKN1B,NCOA1,RBPJ,MAML1,YY1,STAT3
il6_7pathway	IL6-mediated signaling events	0.442514976632757	-0.815280969609143	43	9	0.0211267605633803	426	2226	7409,3716,3572,5879,5781,6772,4170,6774,1432	VAV1,JAK1,IL6ST,RAC1,PTPN11,STAT1,MCL1,STAT3,MAPK14
nfkappabcanonicalpathway	Canonical NF-kappaB pathway	0.457306911788962	-0.782400534089549	23	5	0.0117370892018779	426	2226	7323,1540,7128,23085,329	UBE2D3,CYLD,TNFAIP3,ERC1,BIRC2
alk1_2pathway	ALK1 pathway	0.471428920038168	-0.751986941108249	3	1	0.00234741784037559	426	2226	2280	FKBP1A
aurora_kinase_pathway	Signaling by Aurora kinases	0.471428920038168	-0.751986941108249	3	1	0.00234741784037559	426	2226	9212	AURKB
aurora_c_pathway	Aurora C signaling	0.471428920038168	-0.751986941108249	3	1	0.00234741784037559	426	2226	9212	AURKB
a4b1_a4b7_pathway	a4b1 and a4b7 Integrin signaling	0.471428920038168	-0.751986941108249	3	1	0.00234741784037559	426	2226	3688	ITGB1
tcr_pathway	TCR signaling in naive CD4+ T cells	0.484606980019261	-0.724417067031836	60	12	0.028169014084507	426	2226	5170,7409,7454,5906,6464,998,5728,1445,4690,5781,84876,9020	PDPK1,VAV1,WAS,RAP1A,SHC1,CDC42,PTEN,CSK,NCK1,PTPN11,ORAI1,MAP3K14
reelinpathway	Reelin signaling pathway	0.489944532404144	-0.713463093460191	29	6	0.0140845070422535	426	2226	9181,1399,1020,5906,7804,3688	ARHGEF2,CRKL,CDK5,RAP1A,LRP8,ITGB1
ar_tf_pathway	Regulation of Androgen receptor activity	0.495484674547852	-0.70221885495812	50	10	0.0234741784037559	426	2226	4193,11143,51564,8648,3301,1432,6605,29843,10499,10498	MDM2,KAT7,HDAC7,NCOA1,DNAJA1,MAPK14,SMARCE1,SENP1,NCOA2,CARM1
cd8tcrdownstreampathway	Downstream signaling in naive CD8+ T cells	0.495484674547852	-0.70221885495812	50	10	0.0234741784037559	426	2226	805,4775,5894,5778,4773,2002,5594,5605,3105,5595	CALM2,NFATC3,RAF1,PTPN7,NFATC2,ELK1,MAPK1,MAP2K2,HLA-A,MAPK3
a4b1_paxdep_pathway	Paxillin-dependent events mediated by a4b1	0.507153367070241	-0.678941821982248	19	4	0.00938967136150235	426	2226	1399,5566,5879,3688	CRKL,PRKACA,RAC1,ITGB1
ecadherin_keratinocyte_pathway	E-cadherin signaling in keratinocytes	0.507153367070241	-0.678941821982248	19	4	0.00938967136150235	426	2226	387,7408,208,5879	RHOA,VASP,AKT2,RAC1
circadianpathway	Circadian rhythm pathway	0.519509984000453	-0.654869250147349	14	3	0.00704225352112676	426	2226	8914,11091,406	TIMELESS,WDR5,ARNTL
il2_stat5pathway	IL2 signaling events mediated by STAT5	0.525828402924984	-0.642780349649707	30	6	0.0140845070422535	426	2226	596,890,598,3716,6464,5781	BCL2,CCNA2,BCL2L1,JAK1,SHC1,PTPN11
trail_pathway	TRAIL signaling pathway	0.536888052117095	-0.621965675261656	25	5	0.0117370892018779	426	2226	7818,5594,8772,5595,8837	DAP3,MAPK1,FADD,MAPK3,CFLAR
epha_fwdpathway	EPHA forward signaling	0.560653405131382	-0.578652380551585	31	6	0.0140845070422535	426	2226	1399,1020,387,6093,4067,7410	CRKL,CDK5,RHOA,ROCK1,LYN,VAV2
fcer1pathway	Fc-epsilon receptor I signaling in mast cells	0.567600772958199	-0.566336971896263	58	11	0.0258215962441315	426	2226	7409,6464,5894,5781,7456,4773,4067,5594,3265,5605,5595	VAV1,SHC1,RAF1,PTPN11,WIPF1,NFATC2,LYN,MAPK1,HRAS,MAP2K2,MAPK3
syndecan_pathway	Proteogylcan syndecan-mediated signaling events	0.572720544002711	-0.557357388036594	4	1	0.00234741784037559	426	2226	6383	SDC2
glypican_1pathway	Glypican 1 network	0.574624961524314	-0.554037691813652	26	5	0.0117370892018779	426	2226	7040,4087,4067,351,5621	TGFB1,SMAD2,LYN,APP,PRNP
s1p_meta_pathway	Sphingosine 1-phosphate (S1P) pathway	0.592301809152139	-0.523738961251512	21	4	0.00938967136150235	426	2226	2768,9294,2771,4363	GNA12,S1PR2,GNAI2,ABCC1
erbb4_pathway	ErbB4 signaling events	0.594230516513406	-0.5204879599627	32	6	0.0140845070422535	426	2226	6868,4193,6464,5594,23118,5595	ADAM17,MDM2,SHC1,MAPK1,TAB2,MAPK3
avb3_opn_pathway	Osteopontin-mediated events	0.594230516513406	-0.5204879599627	32	6	0.0140845070422535	426	2226	387,9020,998,5594,5879,5595	RHOA,MAP3K14,CDC42,MAPK1,RAC1,MAPK3
pi3kplctrkpathway	Trk receptor signaling mediated by PI3K and PLC-gamma	0.594230516513406	-0.5204879599627	32	6	0.0140845070422535	426	2226	5170,7534,1385,6464,7533,2309	PDPK1,YWHAZ,CREB1,SHC1,YWHAH,FOXO3
alphasynuclein_pathway	Alpha-synuclein signaling	0.594230516513406	-0.5204879599627	32	6	0.0140845070422535	426	2226	2280,1457,5594,4067,11315,5595	FKBP1A,CSNK2A1,MAPK1,LYN,PARK7,MAPK3
cdc42_pathway	CDC42 signaling events	0.598061374897606	-0.514061896689937	70	13	0.0305164319248826	426	2226	998,10092,5894,3984,5879,10096,7410,5594,1386,1432,3265,1072,5595	CDC42,ARPC5,RAF1,LIMK1,RAC1,ACTR3,VAV2,MAPK1,ATF2,MAPK14,HRAS,CFL1,MAPK3
p38gammadeltapathway	Signaling mediated by p38-gamma and p38-delta	0.598097637575944	-0.514001264820812	10	2	0.00469483568075117	426	2226	3925,29904	STMN1,EEF2K
fak_pathway	Signaling events mediated by focal adhesion kinase	0.60239751264961	-0.506837731572691	54	10	0.0234741784037559	426	2226	824,387,9844,5894,5879,3688,3693,5594,2113,9815	CAPN2,RHOA,ELMO1,RAF1,RAC1,ITGB1,ITGB5,MAPK1,ETS1,GIT2
anthraxpathway	Cellular roles of Anthrax toxin	0.631465788855849	-0.459711513075786	22	4	0.00938967136150235	426	2226	805,5594,5605,5595	CALM2,MAPK1,MAP2K2,MAPK3
a4b1_paxindep_pathway	Paxillin-independent events mediated by a4b1 and a4b7	0.631465788855849	-0.459711513075786	22	4	0.00938967136150235	426	2226	1399,387,5879,3688	CRKL,RHOA,RAC1,ITGB1
hdac_classii_pathway	Signaling events mediated by HDAC Class II	0.657067617873146	-0.419968346656129	34	6	0.0140845070422535	426	2226	5905,9612,156,7329,51564,8625	RANGAP1,NCOR2,GRK2,UBE2I,HDAC7,RFXANK
hif2pathway	HIF-2-alpha transcription factor network	0.657067617873146	-0.419968346656129	34	6	0.0140845070422535	426	2226	10370,2002,2113,7428,6513,54583	CITED2,ELK1,ETS1,VHL,SLC2A1,EGLN1
syndecan_3_pathway	Syndecan-3-mediated signaling events	0.65934362002244	-0.416510453937464	17	3	0.00704225352112676	426	2226	5663,83464,51107	PSEN1,APH1B,APH1A
epha2_fwdpathway	EPHA2 forward signaling	0.65934362002244	-0.416510453937464	17	3	0.00704225352112676	426	2226	387,5879,7410	RHOA,RAC1,VAV2
insulin_glucose_pathway	Insulin-mediated glucose transport	0.677205490906209	-0.389780520507049	29	5	0.0117370892018779	426	2226	805,7534,7533,9322,208	CALM2,YWHAZ,YWHAH,TRIP10,AKT2
fgf_pathway	FGF signaling pathway	0.703039977127885	-0.352341522319055	47	8	0.0187793427230047	426	2226	5170,6464,6195,5781,6772,6383,5594,5595	PDPK1,SHC1,RPS6KA1,PTPN11,STAT1,SDC2,MAPK1,MAPK3
cd40_pathway	CD40/CD40L signaling	0.707480908505642	-0.346044634273153	30	5	0.0117370892018779	426	2226	7128,9020,330,1432,329	TNFAIP3,MAP3K14,BIRC3,MAPK14,BIRC2
cdc42_reg_pathway	Regulation of CDC42 activity	0.707480908505642	-0.346044634273153	30	5	0.0117370892018779	426	2226	55114,29127,139818,998,7410	ARHGAP17,RACGAP1,DOCK11,CDC42,VAV2
bmppathway	BMP receptor signaling	0.713529442988369	-0.337531577340796	36	6	0.0140845070422535	426	2226	4086,5594,57154,4089,10106,331	SMAD1,MAPK1,SMURF1,SMAD4,CTDSP2,XIAP
nfkappabalternativepathway	Alternative NF-kappaB pathway	0.720880496371641	-0.327281902492114	6	1	0.00234741784037559	426	2226	9020	MAP3K14
nectin_pathway	Nectin adhesion pathway	0.733710179148322	-0.309641179638485	25	4	0.00938967136150235	426	2226	998,5879,7410,23396	CDC42,RAC1,VAV2,PIP5K1C
a6b1_a6b4_integrin_pathway	a6b1 and a6b4 Integrin signaling	0.735716966843543	-0.306909790132949	31	5	0.0117370892018779	426	2226	7534,6464,7533,3265,3688	YWHAZ,SHC1,YWHAH,HRAS,ITGB1
il12_2pathway	IL12-mediated signaling events	0.758378676935988	-0.276572444291029	61	10	0.0234741784037559	426	2226	6778,7879,10912,4616,6772,3594,6774,1432,1386,3105	STAT6,RAB7A,GADD45G,GADD45B,STAT1,IL12RB1,STAT3,MAPK14,ATF2,HLA-A
ptp1bpathway	Signaling events mediated by PTP1B	0.769094929790067	-0.262540871334478	50	8	0.0187793427230047	426	2226	387,7295,6464,1445,4904,4067,6774,823	RHOA,TXN,SHC1,CSK,YBX1,LYN,STAT3,CAPN1
rapid_gr_pathway	Rapid glucocorticoid signaling	0.774441265989951	-0.255613456745874	7	1	0.00234741784037559	426	2226	1432	MAPK14
nfkappabatypicalpathway	Atypical NF-kappaB pathway	0.780479492664504	-0.247846813984897	14	2	0.00469483568075117	426	2226	409,1432	ARRB2,MAPK14
p38alphabetapathway	Regulation of p38-alpha and p38-beta	0.789060173586163	-0.236912695409151	27	4	0.00938967136150235	426	2226	4067,1432,83605,5879	LYN,MAPK14,CCM2,RAC1
avb3_integrin_pathway	Integrins in angiogenesis	0.806060149742402	-0.215596911788037	46	7	0.0164319248826291	426	2226	1027,387,6093,5594,5879,5595,5781	CDKN1B,RHOA,ROCK1,MAPK1,RAC1,MAPK3,PTPN11
arf6_pathway	Arf6 signaling events	0.808366281148794	-0.212740004925262	34	5	0.0117370892018779	426	2226	154,409,4690,23303,9744	ADRB2,ARRB2,NCK1,KIF13B,ACAP1
erbb1_internalization_pathway	Internalization of ErbB1	0.808366281148794	-0.212740004925262	34	5	0.0117370892018779	426	2226	29924,7323,9146,998,5894	EPN1,UBE2D3,HGS,CDC42,RAF1
hif1apathway	Hypoxic and oxygen homeostasis regulation of HIF-1-alpha	0.81293278808248	-0.207106844337067	15	2	0.00469483568075117	426	2226	9978,7428	RBX1,VHL
et_egfrpathway	EGFR-dependent Endothelin signaling events	0.817743663780336	-0.201206360951552	8	1	0.00234741784037559	426	2226	3265	HRAS
il4_2pathway	IL4-mediated signaling events	0.839648464526334	-0.174771969349594	60	9	0.0211267605633803	426	2226	3662,3716,6464,6778,2971,1432,4603,2113,9655	IRF4,JAK1,SHC1,STAT6,GTF3A,MAPK14,MYBL1,ETS1,SOCS5
cd8tcrpathway	TCR signaling in naive CD8+ T cells	0.840781501883782	-0.173423460275373	48	7	0.0164319248826291	426	2226	5170,7409,84876,5906,9020,1445,3105	PDPK1,VAV1,ORAI1,RAP1A,MAP3K14,CSK,HLA-A
syndecan_4_pathway	Syndecan-4-mediated signaling events	0.872000431156493	-0.136965360627761	31	4	0.00938967136150235	426	2226	387,5879,3688,1785	RHOA,RAC1,ITGB1,DNM2
nephrin_neph1_pathway	Nephrin/Neph1 signaling in the kidney podocyte	0.900071881695216	-0.105280650296909	26	3	0.00704225352112676	426	2226	409,4690,5879	ARRB2,NCK1,RAC1
lysophospholipid_pathway	LPA receptor mediated events	0.900436227311422	-0.104875936072789	65	9	0.0211267605633803	426	2226	2768,387,2771,4067,3265,9138,115,5879,113	GNA12,RHOA,GNAI2,LYN,HRAS,ARHGEF1,ADCY9,RAC1,ADCY7
fra_pathway	Validated transcriptional targets of AP1 family members Fra1 and Fra2	0.91419168899245	-0.0897150041426073	34	4	0.00938967136150235	426	2226	4773,890,4775,7392	NFATC2,CCNA2,NFATC3,USF2
nfat_tfpathway	Calcineurin-regulated NFAT-dependent transcription in lymphocytes	0.920679933944415	-0.0826428232731647	48	6	0.0140845070422535	426	2226	805,3662,4773,4775,1869,5796	CALM2,IRF4,NFATC2,NFATC3,E2F1,PTPRK
il1pathway	IL1-mediated signaling events	0.925217764567697	-0.0777261480226566	35	4	0.00938967136150235	426	2226	7335,23118,54472,23085	UBE2V1,TAB2,TOLLIP,ERC1
il12_stat4pathway	IL12 signaling mediated by STAT4	0.926052104709253	-0.0768247773344685	28	3	0.00704225352112676	426	2226	7040,6774,9063	TGFB1,STAT3,PIAS2
hnf3apathway	FOXA1 transcription factor network	0.935723090973115	-0.0664356892521524	43	5	0.0117370892018779	426	2226	1027,672,7026,162,522	CDKN1B,BRCA1,NR2F2,AP1B1,ATP5PF
tcrjnkpathway	JNK signaling in the CD4+ TCR pathway	0.937324360388871	-0.0647258876081098	13	1	0.00234741784037559	426	2226	1399	CRKL
hedgehog_2pathway	Signaling events mediated by the Hedgehog family	0.942873731107774	-0.0588229065785446	22	2	0.00469483568075117	426	2226	156,409	GRK2,ARRB2
hnf3bpathway	FOXA2 and FOXA3 transcription factor networks	0.943637066617992	-0.0580136500900083	44	5	0.0117370892018779	426	2226	34,1385,4763,622,7037	ACADM,CREB1,NF1,BDH1,TFRC
wnt_beta_catenin_pathway	Regulation of Wnt-mediated beta catenin signaling and target gene transcription	0.949966743898609	-0.0513283014228061	78	10	0.0234741784037559	426	2226	8313,8454,6597,29969,7534,10856,7533,10499,3066,113	AXIN2,CUL1,SMARCA4,MDFIC,YWHAZ,RUVBL2,YWHAH,NCOA2,HDAC2,ADCY7
amb2_neutrophils_pathway	amb2 Integrin signaling	0.96723402229297	-0.0333148042322168	48	5	0.0117370892018779	426	2226	387,6093,3384,4067,6404	RHOA,ROCK1,ICAM2,LYN,SELPLG
ephrinbrevpathway	Ephrin B reverse signaling	0.976722324306247	-0.0235528799185705	27	2	0.00469483568075117	426	2226	4067,5879	LYN,RAC1
wnt_signaling_pathway	Wnt signaling network	0.98062003350627	-0.0195702201284226	28	2	0.00469483568075117	426	2226	4041,8323	LRP5,FZD6
il23pathway	IL23-mediated signaling events	0.982512630575054	-0.0176420797742237	37	3	0.00704225352112676	426	2226	3594,6774,6772	IL12RB1,STAT3,STAT1
hdac_classiii_pathway	Signaling events mediated by HDAC Class III	0.987503649444082	-0.0125750865741125	39	3	0.00704225352112676	426	2226	4209,22933,2309	MEF2D,SIRT2,FOXO3
er_nongenomic_pathway	Plasma membrane estrogen receptor signaling	0.996142596703891	-0.00386486226387949	26	1	0.00234741784037559	426	2226	387	RHOA
ecadherin_1_pathway	E-cadherin signaling events	0.999999999994874	-5.12553194331744e-12	2	0	0	426	2226
glypican_2pathway	Glypican 2 network	0.999999999994874	-5.12553194331744e-12	2	0	0	426	2226
plk2_4pathway	PLK2 and PLK4 events	0.999999999994874	-5.12553194331744e-12	2	0	0	426	2226
glypicanpathway	Glypican pathway	0.99999999999918	-8.20135626078411e-13	3	0	0	426	2226
ephrinarevpathway	Ephrin A  reverse signaling	0.99999999999918	-8.20135626078411e-13	3	0	0	426	2226
hnf3pathway	FOXA transcription factor networks	0.99999999999918	-8.20135626078411e-13	3	0	0	426	2226
ephrinb_ephbpathway	EphrinB-EPHB pathway	1.00000000000592	5.92256355991336e-12	6	0	0	426	2226
ephrina_ephapathway	EphrinA-EPHA pathway	1.00000000001041	1.04103058943714e-11	8	0	0	426	2226
glypican_3pathway	Glypican 3 network	1.00000000001041	1.04103058943714e-11	8	0	0	426	2226
botulinumtoxinpathway	Effects of Botulinum toxin	1.00000000001134	1.13412492270622e-11	9	0	0	426	2226
erbb_network_pathway	ErbB receptor signaling network	1.00000000001982	1.98235085860826e-11	13	0	0	426	2226
cone_pathway	Visual signal transduction: Cones	1.00000000003483	3.48308467421856e-11	23	0	0	426	2226
rhodopsin_pathway	Visual signal transduction: Rods	1.00000000003483	3.48308467421856e-11	23	0	0	426	2226