TermID	Term	Enrichment	logP	Genes in Term	Target Genes in Term	Fraction of Targets in Term	Total Target Genes	Total Genes	Entrez Gene IDs	Gene Symbols
WP2446	Retinoblastoma (RB) in Cancer	3.0348695372375e-11	-24.2182675854302	88	40	0.0477897252090801	837	5312	3015,5894,81620,6240,4998,891,3925,6118,5925,4193,5111,9126,890,1027,994,1786,2956,8819,5983,5591,1871,5877,6241,10592,3275,54443,5557,6117,5426,8030,1633,7027,1869,3148,7029,5928,9133,1017,1870,11124	H2AFZ,RAF1,CDT1,RRM1,ORC1,CCNB1,STMN1,RPA2,RB1,MDM2,PCNA,SMC3,CCNA2,CDKN1B,CDC25B,DNMT1,MSH6,SAP30,RFC3,PRKDC,E2F3,RABIF,RRM2,SMC2,PRMT2,ANLN,PRIM1,RPA1,POLE,CCDC6,DCK,TFDP1,E2F1,HMGB2,TFDP2,RBBP4,CCNB2,CDK2,E2F2,FAF1
WP411	mRNA Processing	9.88133999958054e-11	-23.0377878928834	132	51	0.0609318996415771	837	5312	51362,3182,6431,23451,1660,1659,6634,56339,8559,10992,10914,84991,3181,22826,9343,6429,6434,4904,10898,4670,5094,1477,10772,6733,6628,10147,10921,140890,11218,9129,6430,3275,10907,8175,5430,6626,1665,6426,57794,1198,8449,10236,10972,27316,5496,9128,6428,2521,6637,6625,8899	CDC40,HNRNPAB,SRSF6,SF3B1,DHX9,DHX8,SNRPD3,METTL3,PRPF18,SF3B2,PAPOLA,RBM17,HNRNPA2B1,DNAJC8,EFTUD2,SRSF4,TRA2B,YBX1,CPSF4,HNRNPM,PCBP2,CSTF1,SRSF10,SRPK2,SNRPB,SUGP2,RNPS1,SREK1,DDX20,PRPF3,SRSF5,PRMT2,TXNL4A,SF3A2,POLR2A,SNRPA,DHX15,SRSF1,SUGP1,CLK3,DHX16,HNRNPR,TMED10,RBMX,PPM1G,PRPF4,SRSF3,FUS,SNRPG,SNRNP70,PRPF4B
WP179	Cell Cycle	1.95025101014411e-07	-15.450137563516	105	38	0.045400238948626	837	5312	55388,9232,10926,375,4998,891,10459,5925,890,4193,5111,51564,4174,1027,994,23595,5347,7040,5591,1871,990,9088,4221,4171,5933,1874,7027,1869,7534,11200,7533,1017,9133,1870,9700,4089,3066,1029	MCM10,PTTG1,DBF4,ARF1,ORC1,CCNB1,MAD2L2,RB1,CCNA2,MDM2,PCNA,HDAC7,MCM5,CDKN1B,CDC25B,ORC3,PLK1,TGFB1,PRKDC,E2F3,CDC6,PKMYT1,MEN1,MCM2,RBL1,E2F4,TFDP1,E2F1,YWHAZ,CHEK2,YWHAH,CDK2,CCNB2,E2F2,ESPL1,SMAD4,HDAC2,CDKN2A
WP1984	Integrated Breast Cancer Pathway	9.19313486877155e-07	-13.8996386553727	154	48	0.0573476702508961	837	5312	4149,7249,4763,56911,5879,64781,6597,641,152789,5925,4193,5906,998,5728,5296,4436,596,994,1385,79902,2956,1263,578,5347,3845,672,4953,27005,8772,6009,7248,4087,3716,28996,1869,6772,5371,55526,7517,6794,11200,57178,2197,4086,5594,1017,4089,1453	MAX,TSC2,NF1,MAP3K7CL,RAC1,CERK,SMARCA4,BLM,JAKMIP1,RB1,MDM2,RAP1A,CDC42,PTEN,PIK3R2,MSH2,BCL2,CDC25B,CREB1,NUP85,MSH6,PLK3,BAK1,PLK1,KRAS,BRCA1,ODC1,USP21,FADD,RHEB,TSC1,SMAD2,JAK1,HIPK2,E2F1,STAT1,PML,DHTKD1,XRCC3,STK11,CHEK2,ZMIZ1,FAU,SMAD1,MAPK1,CDK2,SMAD4,CSNK1D
WP111	Electron Transport Chain	1.57690040455109e-06	-13.3600494069866	92	33	0.039426523297491	837	5312	4698,1329,4729,1355,4719,4712,29796,1327,4697,506,522,6389,374291,4724,4723,4695,4710,4728,4715,4696,93974,4701,4707,9551,292,6390,518,9167,1351,9377,7388,498,4725	NDUFA5,COX5B,NDUFV2,COX15,NDUFS1,NDUFB6,UQCR10,COX4I1,NDUFA4,ATP5F1B,ATP5PF,SDHA,NDUFS7,NDUFS4,NDUFV1,NDUFA2,NDUFB4,NDUFS8,NDUFB9,NDUFA3,ATP5IF1,NDUFA7,NDUFB1,ATP5MF,SLC25A5,SDHB,ATP5MC3,COX7A2L,COX8A,COX5A,UQCRH,ATP5F1A,NDUFS5
WP45	G1 to S cell cycle control	5.27534987884063e-06	-12.1524655530594	68	26	0.031063321385902	837	5312	23649,5558,1871,4998,891,4171,6117,5557,6118,1031,5925,5111,4193,5426,5933,1874,4174,7027,1869,1027,1385,23595,7029,1870,1017,1029	POLA2,PRIM2,E2F3,ORC1,CCNB1,MCM2,RPA1,PRIM1,RPA2,CDKN2C,RB1,PCNA,MDM2,POLE,RBL1,E2F4,MCM5,TFDP1,E2F1,CDKN1B,CREB1,ORC3,TFDP2,E2F2,CDK2,CDKN2A
WP623	Oxidative phosphorylation	8.44401237066057e-06	-11.6820529629555	54	22	0.026284348864994	837	5312	4698,4729,4719,4712,4697,506,4701,9551,4707,522,374291,4724,4723,4695,518,4710,126328,4728,4715,4725,498,4696	NDUFA5,NDUFV2,NDUFS1,NDUFB6,NDUFA4,ATP5F1B,NDUFA7,ATP5MF,NDUFB1,ATP5PF,NDUFS7,NDUFS4,NDUFV1,NDUFA2,ATP5MC3,NDUFB4,NDUFA11,NDUFS8,NDUFB9,NDUFS5,ATP5F1A,NDUFA3
WP466	DNA Replication	2.4616740315811e-05	-10.6120838458188	42	18	0.021505376344086	837	5312	23649,55388,5983,5558,81620,10926,990,4998,4171,5982,6117,5557,6118,5111,5426,4174,23595,1017	POLA2,MCM10,RFC3,PRIM2,CDT1,DBF4,CDC6,ORC1,MCM2,RFC2,RPA1,PRIM1,RPA2,PCNA,POLE,MCM5,ORC3,CDK2
WP3657	Hematopoietic Stem Cell Gene Regulation by GABP alpha/beta Complex	3.02343500616021e-05	-10.4065318606963	22	12	0.014336917562724	837	5312	1788,5728,2551,2120,6597,596,4170,598,4089,1786,2309,7014	DNMT3A,PTEN,GABPA,ETV6,SMARCA4,BCL2,MCL1,BCL2L1,SMAD4,DNMT1,FOXO3,TERF2
WP2034	Leptin signaling pathway	5.20346065969536e-05	-9.86360154925753	76	26	0.031063321385902	837	5312	387,5894,6195,5879,5562,598,2002,1432,5140,5605,5595,30837,3840,998,6464,3716,5728,5296,6772,5781,8648,6093,1385,6774,5594,3265	RHOA,RAF1,RPS6KA1,RAC1,PRKAA1,BCL2L1,ELK1,MAPK14,PDE3B,MAP2K2,MAPK3,SOCS7,KPNA4,CDC42,SHC1,JAK1,PTEN,PIK3R2,STAT1,PTPN11,NCOA1,ROCK1,CREB1,STAT3,MAPK1,HRAS
WP2526	PDGF Pathway	9.02411039973118e-05	-9.3130255362766	38	16	0.019115890083632	837	5312	7409,387,998,3716,6464,5894,5879,7410,5781,6772,23647,2002,6774,5594,3265,5595	VAV1,RHOA,CDC42,JAK1,SHC1,RAF1,RAC1,VAV2,PTPN11,STAT1,ARFIP2,ELK1,STAT3,MAPK1,HRAS,MAPK3
WP1971	Integrated Cancer Pathway	0.000104836766892751	-9.16310601847418	46	18	0.021505376344086	837	5312	5347,672,641,5925,4087,4193,3716,5728,1869,4436,6772,1027,596,994,11200,4217,1017,2956	PLK1,BRCA1,BLM,RB1,SMAD2,MDM2,JAK1,PTEN,E2F1,MSH2,STAT1,CDKN1B,BCL2,CDC25B,CHEK2,MAP3K5,CDK2,MSH6
WP23	B Cell Receptor Signaling Pathway	0.000148591045513111	-8.81431268649282	98	30	0.03584229390681	837	5312	5170,26469,4149,4690,5894,6195,5879,7410,1871,4773,4209,2002,4067,1432,2113,5605,23396,7409,1399,3662,4775,998,6464,5296,5781,1385,5594,975,1386,3265	PDPK1,PTPN18,MAX,NCK1,RAF1,RPS6KA1,RAC1,VAV2,E2F3,NFATC2,MEF2D,ELK1,LYN,MAPK14,ETS1,MAP2K2,PIP5K1C,VAV1,CRKL,IRF4,NFATC3,CDC42,SHC1,PIK3R2,PTPN11,CREB1,MAPK1,CD81,ATF2,HRAS
WP477	Cytoplasmic Ribosomal Proteins	0.000180635771523007	-8.61902786614621	90	28	0.033452807646356	837	5312	6159,6209,6187,11224,6181,6195,6132,6169,6128,6204,6229,6138,6157,6203,9801,3921,6135,25873,6147,6167,6161,6139,6233,6208,6176,6143,2197,6231	RPL29,RPS15,RPS2,RPL35,RPLP2,RPS6KA1,RPL8,RPL38,RPL6,RPS10,RPS24,RPL15,RPL27A,RPS9,MRPL19,RPSA,RPL11,RPL36,RPL23A,RPL37,RPL32,RPL17,RPS27A,RPS14,RPLP1,RPL19,FAU,RPS26
WP127	IL-5 Signaling Pathway	0.000186824792178142	-8.58533932053638	40	16	0.019115890083632	837	5312	3716,6464,5894,6195,5296,5781,6772,596,3845,2002,6774,5594,4067,2309,5605,5595	JAK1,SHC1,RAF1,RPS6KA1,PIK3R2,PTPN11,STAT1,BCL2,KRAS,ELK1,STAT3,MAPK1,LYN,FOXO3,MAP2K2,MAPK3
WP2332	Interleukin-11 Signaling Pathway	0.000195365098239891	-8.54064045130085	44	17	0.020310633213859	837	5312	7040,5170,5894,6195,5605,5595,3716,332,3572,5296,6772,5781,596,1385,5594,6774,3265	TGFB1,PDPK1,RAF1,RPS6KA1,MAP2K2,MAPK3,JAK1,BIRC5,IL6ST,PIK3R2,STAT1,PTPN11,BCL2,CREB1,MAPK1,STAT3,HRAS
WP437	EGF/EGFR Signaling Pathway	0.000244800298020041	-8.31506778992472	162	43	0.0513739545997611	837	5312	9185,5894,6195,5879,7410,29924,4205,3925,1432,8027,1399,7409,5906,5111,6464,998,5728,5899,9138,5296,5781,163,1385,6774,10006,1072,5170,4690,4605,3845,4209,2002,5605,4216,9146,3716,1445,1869,6772,6093,5594,3265,1175	REPS2,RAF1,RPS6KA1,RAC1,VAV2,EPN1,MEF2A,STMN1,MAPK14,STAM,CRKL,VAV1,RAP1A,PCNA,SHC1,CDC42,PTEN,RALB,ARHGEF1,PIK3R2,PTPN11,AP2B1,CREB1,STAT3,ABI1,CFL1,PDPK1,NCK1,MYBL2,KRAS,MEF2D,ELK1,MAP2K2,MAP3K4,HGS,JAK1,CSK,E2F1,STAT1,ROCK1,MAPK1,HRAS,AP2S1
WP400	p38 MAPK Signaling Pathway	0.000328940393443276	-8.01963399855751	34	14	0.016726403823178	837	5312	8569,3150,4149,998,6464,5879,6772,4209,1385,2002,4217,1432,1386,3265	MKNK1,HMGN1,MAX,CDC42,SHC1,RAC1,STAT1,MEF2D,CREB1,ELK1,MAP3K5,MAPK14,ATF2,HRAS
WP78	TCA Cycle	0.000420898154836958	-7.77311966604873	17	9	0.010752688172043	837	5312	6390,8802,3419,4191,1431,8801,4967,3420,6389	SDHB,SUCLG1,IDH3A,MDH2,CS,SUCLG2,OGDH,IDH3B,SDHA
WP2032	Human Thyroid Stimulating Hormone (TSH) signaling pathway	0.000476949314976908	-7.64810033063175	68	22	0.026284348864994	837	5312	5170,5894,6195,1432,7270,5595,2778,2768,5925,5906,3716,5296,1869,6772,1027,1385,6774,5594,1017,2771,3265,103910	PDPK1,RAF1,RPS6KA1,MAPK14,TTF1,MAPK3,GNAS,GNA12,RB1,RAP1A,JAK1,PIK3R2,E2F1,STAT1,CDKN1B,CREB1,STAT3,MAPK1,CDK2,GNAI2,HRAS,MYL12B
WP366	TGF-beta Signaling Pathway	0.000516575015512637	-7.56829004178482	133	36	0.043010752688172	837	5312	5894,5879,8454,4205,7329,2113,1432,351,6464,998,51377,5296,55802,9972,1386,11171,7040,387,7071,9978,1316,5605,9146,4087,5933,1874,8312,7027,5371,9063,3688,6093,9133,57154,5594,4089	RAF1,RAC1,CUL1,MEF2A,UBE2I,ETS1,MAPK14,APP,SHC1,CDC42,UCHL5,PIK3R2,DCP1A,NUP153,ATF2,STRAP,TGFB1,RHOA,KLF10,RBX1,KLF6,MAP2K2,HGS,SMAD2,RBL1,E2F4,AXIN1,TFDP1,PML,PIAS2,ITGB1,ROCK1,CCNB2,SMURF1,MAPK1,SMAD4
WP524	G13 Signaling Pathway	0.000670827235829508	-7.30699892682767	40	15	0.017921146953405	837	5312	4216,805,23191,387,7454,998,3984,9138,5879,5296,397,6093,5305,1072,6242	MAP3K4,CALM2,CYFIP1,RHOA,WAS,CDC42,LIMK1,ARHGEF1,RAC1,PIK3R2,ARHGDIB,ROCK1,PIP4K2A,CFL1,RTKN
WP3879	4-hydroxytamoxifen, Dexamethasone, and Retinoic Acids Regulation of p27 Expression	0.000725049677455635	-7.22927038482857	18	9	0.010752688172043	837	5312	7248,8569,4217,5594,5894,5605,55872,5562,5595	TSC1,MKNK1,MAP3K5,MAPK1,RAF1,MAP2K2,PBK,PRKAA1,MAPK3
WP3676	BDNF-TrkB Signaling	0.000886726192089216	-7.02797431317481	33	13	0.015531660692951	837	5312	9456,7248,8569,4893,6464,7249,6195,3845,1385,5594,3265,6009,29904	HOMER1,TSC1,MKNK1,NRAS,SHC1,TSC2,RPS6KA1,KRAS,CREB1,MAPK1,HRAS,RHEB,EEF2K
WP3878	ATM Signaling Network in Development and Disease	0.00116218595131496	-6.75745260640617	46	16	0.019115890083632	837	5312	1020,3150,7249,5591,5562,3014,6794,64421,11200,9212,80254,4217,5536,1386,10155,23300	CDK5,HMGN1,TSC2,PRKDC,PRKAA1,H2AFX,STK11,DCLRE1C,CHEK2,AURKB,CEP63,MAP3K5,PPP5C,ATF2,TRIM28,ATMIN
WP404	Nucleotide Metabolism	0.00118689577870528	-6.73641396947965	19	9	0.010752688172043	837	5312	159,6723,10797,5634,6240,3614,6241,158,4946	ADSS,SRM,MTHFD2,PRPS2,RRM1,IMPDH1,RRM2,ADSL,OAZ1
WP3844	PI3K-AKT-mTOR signaling pathway and therapeutic opportunities	0.00119004823111331	-6.73376144233272	30	12	0.014336917562724	837	5312	4893,7249,5728,9821,5296,1027,9776,3845,3265,2309,6009,7942	NRAS,TSC2,PTEN,RB1CC1,PIK3R2,CDKN1B,ATG13,KRAS,HRAS,FOXO3,RHEB,TFEB
WP2261	Signaling Pathways in Glioblastoma	0.00162530985979564	-6.42205679842696	83	24	0.028673835125448	837	5312	5170,4893,7249,4763,5894,208,3845,672,2309,5605,5595,1031,5925,7248,4193,5728,5296,1869,1027,5594,1017,3265,1029,2956	PDPK1,NRAS,TSC2,NF1,RAF1,AKT2,KRAS,BRCA1,FOXO3,MAP2K2,MAPK3,CDKN2C,RB1,TSC1,MDM2,PTEN,PIK3R2,E2F1,CDKN1B,MAPK1,CDK2,HRAS,CDKN2A,MSH6
WP2377	Integrated Pancreatic Cancer Pathway	0.00166408103376112	-6.39848223959509	197	47	0.0561529271206691	837	5312	5894,5879,9232,6240,375,641,1432,3925,351,2280,4193,5111,5906,890,5728,1027,596,7159,1385,7040,5347,2512,9821,4690,3845,672,2287,8772,6009,5595,355,4216,4087,10555,5933,1874,1869,6772,5371,51719,6794,11200,4217,5594,1017,4089,823	RAF1,RAC1,PTTG1,RRM1,ARF1,BLM,MAPK14,STMN1,APP,FKBP1A,MDM2,PCNA,RAP1A,CCNA2,PTEN,CDKN1B,BCL2,TP53BP2,CREB1,TGFB1,PLK1,FTL,RB1CC1,NCK1,KRAS,BRCA1,FKBP3,FADD,RHEB,MAPK3,FAS,MAP3K4,SMAD2,AGPAT2,RBL1,E2F4,E2F1,STAT1,PML,CAB39,STK11,CHEK2,MAP3K5,MAPK1,CDK2,SMAD4,CAPN1
WP183	Proteasome Degradation	0.00210165326214998	-6.16503097629495	66	20	0.02389486260454	837	5312	7323,3015,3133,5695,5682,5698,5715,3105,5691,5704,3106,5708,6184,5707,5687,5714,5709,3014,6185,5700	UBE2D3,H2AFZ,HLA-E,PSMB7,PSMA1,PSMB9,PSMD9,HLA-A,PSMB3,PSMC4,HLA-B,PSMD2,RPN1,PSMD1,PSMA6,PSMD8,PSMD3,H2AFX,RPN2,PSMC1
WP363	Wnt Signaling Pathway Netpath	0.0022720003383307	-6.08709462921008	53	17	0.020310633213859	837	5312	7248,387,7249,53944,8312,6929,5879,8313,4773,4041,1855,1452,5594,409,1453,1856,55361	TSC1,RHOA,TSC2,CSNK1G1,AXIN1,TCF3,RAC1,AXIN2,NFATC2,LRP5,DVL1,CSNK1A1,MAPK1,ARRB2,CSNK1D,DVL2,PI4K2A
WP138	Androgen receptor signaling pathway	0.00242435778356675	-6.02218862118561	90	25	0.029868578255675	837	5312	9612,387,11143,5879,672,7329,11315,5052,388,5925,4193,998,5728,5296,9063,6093,8648,57178,1385,6774,6605,9604,4089,10499,10498	NCOR2,RHOA,KAT7,RAC1,BRCA1,UBE2I,PARK7,PRDX1,RHOB,RB1,MDM2,CDC42,PTEN,PIK3R2,PIAS2,ROCK1,NCOA1,ZMIZ1,CREB1,STAT3,SMARCE1,RNF14,SMAD4,NCOA2,CARM1
WP2380	Brain-Derived Neurotrophic Factor (BDNF) signaling pathway	0.00243432797670087	-6.01808454546621	144	36	0.043010752688172	837	5312	391,7249,5894,6195,5879,5562,7410,1457,4205,1432,2309,1020,5906,8894,998,6464,1808,5296,5781,4904,1385,6774,1072,5170,23191,6868,4690,2002,5605,5595,5515,5792,4905,6772,5594,3265	RHOG,TSC2,RAF1,RPS6KA1,RAC1,PRKAA1,VAV2,CSNK2A1,MEF2A,MAPK14,FOXO3,CDK5,RAP1A,EIF2S2,CDC42,SHC1,DPYSL2,PIK3R2,PTPN11,YBX1,CREB1,STAT3,CFL1,PDPK1,CYFIP1,ADAM17,NCK1,ELK1,MAP2K2,MAPK3,PPP2CA,PTPRF,NSF,STAT1,MAPK1,HRAS
WP286	IL-3 Signaling Pathway	0.00246911307080091	-6.00389627347455	49	16	0.019115890083632	837	5312	7040,1399,7409,3716,6464,5894,5296,5781,596,598,6774,5594,5566,4067,3265,5595	TGFB1,CRKL,VAV1,JAK1,SHC1,RAF1,PIK3R2,PTPN11,BCL2,BCL2L1,STAT3,MAPK1,PRKACA,LYN,HRAS,MAPK3
WP2868	TCA Cycle Nutrient Utilization and Invasiveness of Ovarian Cancer	0.00267885649292499	-5.92236525725833	5	4	0.004778972520908	837	5312	3716,6774,5594,5595	JAK1,STAT3,MAPK1,MAPK3
WP2533	Glycerophospholipid Biosynthetic Pathway	0.00280592453029777	-5.87602219349472	21	9	0.010752688172043	837	5312	8760,9489,9663,5833,1120,10423,56994,9791,55361	CDS2,PGS1,LPIN2,PCYT2,CHKB,CDIPT,CHPT1,PTDSS1,PI4K2A
WP2507	Nanomaterial induced apoptosis	0.00280592453029777	-5.87602219349472	21	9	0.010752688172043	837	5312	578,839,4170,54205,598,8772,27429,8837,355	BAK1,CASP6,MCL1,CYCS,BCL2L1,FADD,HTRA2,CFLAR,FAS
WP1528	Physiological and Pathological Hypertrophy  of the Heart	0.00304340424629919	-5.79477857223076	25	10	0.01194743130227	837	5312	805,5530,387,3572,5879,5532,6774,1432,5594,50804	CALM2,PPP3CA,RHOA,IL6ST,RAC1,PPP3CB,STAT3,MAPK14,MAPK1,MYEF2
WP615	Senescence and Autophagy in Cancer	0.00308355868051433	-5.78167093322432	106	28	0.033452807646356	837	5312	7040,8804,9821,5894,84335,81631,8678,1432,51100,3663,5925,4193,5111,5728,64422,3572,1869,1027,9776,596,6041,994,5594,3265,4089,3428,1029,64223	TGFB1,CREG1,RB1CC1,RAF1,AKT1S1,MAP1LC3B,BECN1,MAPK14,SH3GLB1,IRF5,RB1,MDM2,PCNA,PTEN,ATG3,IL6ST,E2F1,CDKN1B,ATG13,BCL2,RNASEL,CDC25B,MAPK1,HRAS,SMAD4,IFI16,CDKN2A,MLST8
WP268	Notch Signaling Pathway	0.00338793051466184	-5.6875360116524	46	15	0.017921146953405	837	5312	9612,6868,2648,51107,23220,4242,3516,1855,4853,9794,83464,5663,1856,8650,3066	NCOR2,ADAM17,KAT2A,APH1A,DTX4,MFNG,RBPJ,DVL1,NOTCH2,MAML1,APH1B,PSEN1,DVL2,NUMB,HDAC2
WP707	DNA Damage Response	0.0037453313189197	-5.58724519625468	69	20	0.02389486260454	837	5312	5591,10912,9874,54205,672,891,355,1020,6118,5925,4193,4616,1869,5371,3014,1027,11200,1385,9133,1017	PRKDC,GADD45G,TLK1,CYCS,BRCA1,CCNB1,FAS,CDK5,RPA2,RB1,MDM2,GADD45B,E2F1,PML,H2AFX,CDKN1B,CHEK2,CREB1,CCNB2,CDK2
WP304	Kit receptor signaling pathway	0.00388931297939765	-5.54952274892955	60	18	0.021505376344086	837	5312	5894,6195,1432,4067,2309,5605,5595,7409,1399,6464,5296,9306,6772,5781,596,5594,6774,3265	RAF1,RPS6KA1,MAPK14,LYN,FOXO3,MAP2K2,MAPK3,VAV1,CRKL,SHC1,PIK3R2,SOCS6,STAT1,PTPN11,BCL2,MAPK1,STAT3,HRAS
WP313	Signaling of Hepatocyte Growth Factor Receptor	0.00411302715455164	-5.49359598762784	34	12	0.014336917562724	837	5312	1399,5906,5728,5894,5781,3688,2002,6774,5594,3265,5605,5595	CRKL,RAP1A,PTEN,RAF1,PTPN11,ITGB1,ELK1,STAT3,MAPK1,HRAS,MAP2K2,MAPK3
WP231	TNF alpha Signaling Pathway	0.00456312464324915	-5.38974766133518	94	25	0.029868578255675	837	5312	5347,4893,7295,7128,330,5894,5879,117584,8454,1457,3845,598,329,8772,5595,8837,5515,5708,23118,10010,9020,4217,5594,3265,11140	PLK1,NRAS,TXN,TNFAIP3,BIRC3,RAF1,RAC1,RFFL,CUL1,CSNK2A1,KRAS,BCL2L1,BIRC2,FADD,MAPK3,CFLAR,PPP2CA,PSMD2,TAB2,TANK,MAP3K14,MAP3K5,MAPK1,HRAS,CDC37
WP364	IL-6 signaling pathway	0.00465531306384933	-5.36974611727082	43	14	0.016726403823178	837	5312	7409,3716,6464,3572,5879,5296,5781,6772,8648,598,6774,5594,5605,5595	VAV1,JAK1,SHC1,IL6ST,RAC1,PIK3R2,PTPN11,STAT1,NCOA1,BCL2L1,STAT3,MAPK1,MAP2K2,MAPK3
WP2586	Aryl Hydrocarbon Receptor	0.00532660034650087	-5.23504207798396	48	15	0.017921146953405	837	5312	5925,9612,84722,4893,1728,4763,5894,1869,1027,3845,5594,1017,1316,3265,11140	RB1,NCOR2,PSRC1,NRAS,NQO1,NF1,RAF1,E2F1,CDKN1B,KRAS,MAPK1,CDK2,KLF6,HRAS,CDC37
WP314	Fas Ligand (FasL) pathway and Stress induction of Heat Shock Proteins (HSP) regulation	0.00586193376509665	-5.13927573578548	44	14	0.016726403823178	837	5312	5925,839,7867,5591,596,60,397,54205,4000,8772,11124,8837,355,6709	RB1,CASP6,MAPKAPK3,PRKDC,BCL2,ACTB,ARHGDIB,CYCS,LMNA,FADD,FAF1,CFLAR,FAS,SPTAN1
WP2453	TCA Cycle and Deficiency of Pyruvate Dehydrogenase complex (PDHc)	0.00728265020618831	-4.9222604437082	16	7	0.00836320191158901	837	5312	8801,4190,4967,3419,6389,1431,47	SUCLG2,MDH1,OGDH,IDH3A,SDHA,CS,ACLY
WP2828	Bladder Cancer	0.0074285833907492	-4.90242009916416	32	11	0.013142174432497	837	5312	2261,5925,4193,5296,1869,1612,5594,3265,5605,1029,1613	FGFR3,RB1,MDM2,PIK3R2,E2F1,DAPK1,MAPK1,HRAS,MAP2K2,CDKN2A,DAPK3
WP732	Serotonin Receptor 2 and ELK-SRF/GATA4 signaling	0.0078992710414441	-4.84098479700152	20	8	0.00955794504181601	837	5312	4893,5894,3845,2002,5594,5605,3265,5595	NRAS,RAF1,KRAS,ELK1,MAPK1,MAP2K2,HRAS,MAPK3
WP2509	Nanoparticle triggered autophagic cell death	0.00801358120120862	-4.82661752653043	24	9	0.010752688172043	837	5312	7248,7249,81671,64422,596,8678,51100,115201,10036	TSC1,TSC2,VMP1,ATG3,BCL2,BECN1,SH3GLB1,ATG4A,CHAF1A
WP382	MAPK Signaling Pathway	0.0080506581263021	-4.82200143607327	170	39	0.046594982078853	837	5312	4149,839,4763,5894,5879,8649,5532,3925,5566,1432,1399,5906,998,994,9020,1386,7040,5530,4893,208,57551,9448,8491,3845,2002,5605,5595,355,4216,2768,8569,23118,5597,5778,5534,4217,5536,409,5594	MAX,CASP6,NF1,RAF1,RAC1,LAMTOR3,PPP3CB,STMN1,PRKACA,MAPK14,CRKL,RAP1A,CDC42,CDC25B,MAP3K14,ATF2,TGFB1,PPP3CA,NRAS,AKT2,TAOK1,MAP4K4,MAP4K3,KRAS,ELK1,MAP2K2,MAPK3,FAS,MAP3K4,GNA12,MKNK1,TAB2,MAPK6,PTPN7,PPP3R1,MAP3K5,PPP5C,ARRB2,MAPK1
WP1471	Target Of Rapamycin (TOR) Signaling	0.00883698499003689	-4.72880952498377	37	12	0.014336917562724	837	5312	2280,25989,5564,7248,998,7249,5879,5562,64121,84335,6009,64223	FKBP1A,ULK3,PRKAB1,TSC1,CDC42,TSC2,RAC1,PRKAA1,RRAGC,AKT1S1,RHEB,MLST8
WP3646	Hepatitis C and Hepatocellular Carcinoma	0.0098218283902092	-4.62314798349805	51	15	0.017921146953405	837	5312	7040,330,3716,332,5879,7410,5781,6241,598,672,6774,1870,1432,4089,5595	TGFB1,BIRC3,JAK1,BIRC5,RAC1,VAV2,PTPN11,RRM2,BCL2L1,BRCA1,STAT3,E2F2,MAPK14,SMAD4,MAPK3
WP49	IL-2 Signaling Pathway	0.0100383152724686	-4.60134598034576	42	13	0.015531660692951	837	5312	1399,3716,6464,5894,5781,6772,596,6774,5594,3265,5605,2309,5595	CRKL,JAK1,SHC1,RAF1,PTPN11,STAT1,BCL2,STAT3,MAPK1,HRAS,MAP2K2,FOXO3,MAPK3
WP2916	Interactome of polycomb repressive complex 2 (PRC2)	0.0107260001421166	-4.53508456517168	17	7	0.00836320191158901	837	5312	9774,9967,2145,5928,11329,23512,23515	BCLAF1,THRAP3,EZH1,RBBP4,STK38,SUZ12,MORC3
WP205	IL-7 Signaling Pathway	0.0108093057384026	-4.52734787340803	25	9	0.010752688172043	837	5312	3716,5296,6772,1027,598,5594,6774,5605,5595	JAK1,PIK3R2,STAT1,CDKN1B,BCL2L1,MAPK1,STAT3,MAP2K2,MAPK3
WP2447	Amyotrophic lateral sclerosis (ALS)	0.0111125372649835	-4.4996813247184	38	12	0.014336917562724	837	5312	847,79139,5530,5879,596,598,5532,10452,4217,1432,5605,57679	CAT,DERL1,PPP3CA,RAC1,BCL2,BCL2L1,PPP3CB,TOMM40,MAP3K5,MAPK14,MAP2K2,ALS2
WP2333	Trans-sulfuration pathway	0.0121094437478014	-4.41376965576679	10	5	0.00597371565113501	837	5312	27430,2730,191,4548,1786	MAT2B,GCLM,AHCY,MTR,DNMT1
WP2035	Follicle Stimulating Hormone (FSH) signaling pathway	0.0185008167557805	-3.98994039891129	27	9	0.010752688172043	837	5312	7249,5894,1385,5566,1432,5594,26060,6009,5595	TSC2,RAF1,CREB1,PRKACA,MAPK14,MAPK1,APPL1,RHEB,MAPK3
WP395	IL-4 Signaling Pathway	0.0199426852173111	-3.91489285865481	55	15	0.017921146953405	837	5312	3716,6464,332,6778,4783,5296,5781,6772,2002,6774,5594,1432,1386,5595,9655	JAK1,SHC1,BIRC5,STAT6,NFIL3,PIK3R2,PTPN11,STAT1,ELK1,STAT3,MAPK1,MAPK14,ATF2,MAPK3,SOCS5
WP22	IL-9 Signaling Pathway	0.0208891456134876	-3.86852560355654	19	7	0.00836320191158901	837	5312	3716,6774,5594,5605,5296,5595,6772	JAK1,STAT3,MAPK1,MAP2K2,PIK3R2,MAPK3,STAT1
WP734	Serotonin Receptor 4/6/7 and NR3C Signaling	0.0208891456134876	-3.86852560355654	19	7	0.00836320191158901	837	5312	2778,5906,1385,2002,5594,5605,5595	GNAS,RAP1A,CREB1,ELK1,MAPK1,MAP2K2,MAPK3
WP2525	Trans-sulfuration and one carbon metabolism	0.0212586767793262	-3.85099014792412	32	10	0.01194743130227	837	5312	27430,2730,1788,10797,191,200895,10768,1786,4548,4144	MAT2B,GCLM,DNMT3A,MTHFD2,AHCY,DHFR2,AHCYL1,DNMT1,MTR,MAT2A
WP3611	Photodynamic therapy-induced AP-1 survival signaling.	0.0227973694948597	-3.78111012271019	51	14	0.016726403823178	837	5312	578,5925,890,596,4170,598,2002,4217,1432,1386,7188,1029,8837,355	BAK1,RB1,CCNA2,BCL2,MCL1,BCL2L1,ELK1,MAP3K5,MAPK14,ATF2,TRAF5,CDKN2A,CFLAR,FAS
WP69	T-Cell antigen Receptor (TCR)  Signaling Pathway	0.0230905226781933	-3.76833301931094	91	22	0.026284348864994	837	5312	5170,7040,4690,5894,4773,1432,5605,5595,355,7409,1399,3662,7454,998,6464,5296,5781,9020,1385,1386,5594,3265	PDPK1,TGFB1,NCK1,RAF1,NFATC2,MAPK14,MAP2K2,MAPK3,FAS,VAV1,CRKL,IRF4,WAS,CDC42,SHC1,PIK3R2,PTPN11,MAP3K14,CREB1,ATF2,MAPK1,HRAS
WP3925	Amino Acid metabolism	0.0230905226781933	-3.76833301931094	91	22	0.026284348864994	837	5312	6723,2730,8802,4594,4191,56922,3939,2746,4967,4942,5315,4953,8050,6389,2058,3376,2806,1431,47,4190,34,5832	SRM,GCLM,SUCLG1,MUT,MDH2,MCCC1,LDHA,GLUD1,OGDH,OAT,PKM,ODC1,PDHX,SDHA,EPRS,IARS,GOT2,CS,ACLY,MDH1,ACADM,ALDH18A1
WP2037	Prolactin Signaling Pathway	0.0239143948649326	-3.733274705748	76	19	0.022700119474313	837	5312	5479,5894,5879,7410,2002,1432,5605,5595,7409,6464,3716,5296,3688,6772,5781,7534,6774,5594,3265	PPIB,RAF1,RAC1,VAV2,ELK1,MAPK14,MAP2K2,MAPK3,VAV1,SHC1,JAK1,PIK3R2,ITGB1,STAT1,PTPN11,YWHAZ,STAT3,MAPK1,HRAS
WP3651	Pathways Affected in Adenoid Cystic Carcinoma	0.0239734584000517	-3.73080796059066	66	17	0.020310633213859	837	5312	4149,5591,5894,9874,55914,672,8289,58508,5605,2309,5728,55783,23220,11200,4603,6605,3265	MAX,PRKDC,RAF1,TLK1,ERBIN,BRCA1,ARID1A,KMT2C,MAP2K2,FOXO3,PTEN,CMTR2,DTX4,CHEK2,MYBL1,SMARCE1,HRAS
WP2795	Cardiac Hypertrophic Response	0.027301961122776	-3.60079674337218	57	15	0.017921146953405	837	5312	7040,5170,805,5530,5894,51564,208,5879,4773,4205,9020,5594,1432,5605,5595	TGFB1,PDPK1,CALM2,PPP3CA,RAF1,HDAC7,AKT2,RAC1,NFATC2,MEF2A,MAP3K14,MAPK1,MAPK14,MAP2K2,MAPK3
WP1559	TFs Regulate miRNAs related to cardiac hypertrophy	0.0289747862062257	-3.54132926834348	12	5	0.00597371565113501	837	5312	7040,6774,208,50804,5534	TGFB1,STAT3,AKT2,MYEF2,PPP3R1
WP2290	RalA downstream regulated genes	0.0289747862062257	-3.54132926834348	12	5	0.00597371565113501	837	5312	3845,4893,998,3265,5879	KRAS,NRAS,CDC42,HRAS,RAC1
WP1946	Cori Cycle	0.0292272726615463	-3.53265301035164	16	6	0.00716845878136201	837	5312	2821,6888,5223,6513,5214,3939	GPI,TALDO1,PGAM1,SLC2A1,PFKP,LDHA
WP422	MAPK Cascade	0.0295394503991373	-3.52202860736216	29	9	0.010752688172043	837	5312	4893,5894,3845,2002,1432,5594,5605,3265,5595	NRAS,RAF1,KRAS,ELK1,MAPK14,MAPK1,MAP2K2,HRAS,MAPK3
WP107	Translation Factors	0.0313655688360624	-3.46204452158442	53	14	0.016726403823178	837	5312	1984,8894,8664,23708,27102,1983,7458,8666,26986,8667,10605,8661,1936,29904	EIF5A,EIF2S2,EIF3D,GSPT2,EIF2AK1,EIF5,EIF4H,EIF3G,PABPC1,EIF3H,PAIP1,EIF3A,EEF1D,EEF2K
WP410	Diurnally Regulated Genes with Circadian Orthologs	0.0360675712307901	-3.32236112121623	49	13	0.015531660692951	837	5312	7360,23118,406,2120,1408,10787,3301,9802,1982,5813,10140,51663,11335	UGP2,TAB2,ARNTL,ETV6,CRY2,NCKAP1,DNAJA1,DAZAP2,EIF4G2,PURA,TOB1,ZFR,CBX3
WP531	Mismatch repair	0.0398143904951315	-3.22352686181307	9	4	0.004778972520908	837	5312	5111,2956,6117,4436	PCNA,MSH6,RPA1,MSH2
WP3585	Cytosine methylation	0.0398143904951315	-3.22352686181307	9	4	0.004778972520908	837	5312	200424,53615,4204,1786	TET3,MBD3,MECP2,DNMT1
WP481	Insulin Signaling	0.0407210701882202	-3.20100962544917	161	34	0.040621266427718	837	5312	7249,5894,6195,5879,6513,5562,10211,375,2992,1432,2309,3799,6464,5728,5867,5296,5781,9020,5170,208,9448,8491,2002,5605,6009,5595,5792,4216,7248,8773,5597,4217,5594,3265	TSC2,RAF1,RPS6KA1,RAC1,SLC2A1,PRKAA1,FLOT1,ARF1,GYG1,MAPK14,FOXO3,KIF5B,SHC1,PTEN,RAB4A,PIK3R2,PTPN11,MAP3K14,PDPK1,AKT2,MAP4K4,MAP4K3,ELK1,MAP2K2,RHEB,MAPK3,PTPRF,MAP3K4,TSC1,SNAP23,MAPK6,MAP3K5,MAPK1,HRAS
WP26	Signal Transduction of S1P Receptor	0.0412107302076928	-3.18905661460148	26	8	0.00955794504181601	837	5312	427,29127,9294,5594,2771,208,5597,5595	ASAH1,RACGAP1,S1PR2,MAPK1,GNAI2,AKT2,MAPK6,MAPK3
WP2324	AGE/RAGE pathway	0.0470156066615185	-3.05727567576263	66	16	0.019115890083632	837	5312	387,4087,998,1650,6464,5894,5879,6772,7430,54205,6093,6774,5594,1386,1432,5595	RHOA,SMAD2,CDC42,DDOST,SHC1,RAF1,RAC1,STAT1,EZR,CYCS,ROCK1,STAT3,MAPK1,ATF2,MAPK14,MAPK3
WP2374	Oncostatin M Signaling Pathway	0.0470156066615185	-3.05727567576263	66	16	0.019115890083632	837	5312	5894,3845,1432,5605,5595,6464,3716,3572,6772,5781,1027,1385,1017,5594,6774,3265	RAF1,KRAS,MAPK14,MAP2K2,MAPK3,SHC1,JAK1,IL6ST,STAT1,PTPN11,CDKN1B,CREB1,CDK2,MAPK1,STAT3,HRAS
WP185	Integrin-mediated Cell Adhesion	0.0479575787957345	-3.03743843392256	103	23	0.027479091995221	837	5312	5170,5894,208,5879,7410,3693,5605,9815,824,5906,7408,3696,998,6464,1445,5597,23473,5296,3688,6093,5594,3265,823	PDPK1,RAF1,AKT2,RAC1,VAV2,ITGB5,MAP2K2,GIT2,CAPN2,RAP1A,VASP,ITGB8,CDC42,SHC1,CSK,MAPK6,CAPN7,PIK3R2,ITGB1,ROCK1,MAPK1,HRAS,CAPN1
WP710	DNA Damage Response (only ATM dependent)	0.0490155367779867	-3.01561795402806	114	25	0.029868578255675	837	5312	7040,578,387,4893,208,5879,3845,2309,4216,847,4193,998,6464,5728,81029,8312,5296,1027,596,1855,5594,3265,4089,1029,1856	TGFB1,BAK1,RHOA,NRAS,AKT2,RAC1,KRAS,FOXO3,MAP3K4,CAT,MDM2,CDC42,SHC1,PTEN,WNT5B,AXIN1,PIK3R2,CDKN1B,BCL2,DVL1,MAPK1,HRAS,SMAD4,CDKN2A,DVL2
WP3584	MECP2 and Associated Rett Syndrome	0.0542060490074784	-2.91496277145992	62	15	0.017921146953405	837	5312	6670,200424,5454,9126,1465,4763,4204,2530,1869,3185,6890,10664,2289,4904,1385	SP3,TET3,POU3F2,SMC3,CSRP1,NF1,MECP2,FUT8,E2F1,HNRNPF,TAP1,CTCF,FKBP5,YBX1,CREB1
WP3853	ERK Pathway in Huntington's Disease	0.0559261237190527	-2.88372367848546	14	5	0.00597371565113501	837	5312	1385,2002,5594,3265,5894	CREB1,ELK1,MAPK1,HRAS,RAF1
WP2036	TNF related weak inducer of apoptosis (TWEAK) Signaling Pathway	0.0559783914882253	-2.88278952899423	42	11	0.013142174432497	837	5312	330,5894,208,5879,9020,5594,7188,1432,329,8772,5595	BIRC3,RAF1,AKT2,RAC1,MAP3K14,MAPK1,TRAF5,MAPK14,BIRC2,FADD,MAPK3
WP712	Estrogen signaling pathway	0.0577820476403944	-2.8510771460051	23	7	0.00836320191158901	837	5312	2778,596,1385,2002,5594,5566,1432	GNAS,BCL2,CREB1,ELK1,MAPK1,PRKACA,MAPK14
WP1982	Sterol Regulatory Element-Binding Proteins (SREBP) signalling	0.058143890533742	-2.8448344694452	73	17	0.020310633213859	837	5312	22872,5564,22937,56681,9632,1622,51586,5562,47,4190,22926,949,1385,7528,5566,11236,2222	SEC31A,PRKAB1,SCAP,SAR1A,SEC24C,DBI,MED15,PRKAA1,ACLY,MDH1,ATF6,SCARB1,CREB1,YY1,PRKACA,RNF139,FDFT1
WP51	Regulation of Actin Cytoskeleton	0.0583248758111373	-2.84172659033302	149	31	0.037037037037037	837	5312	10163,387,4893,4659,5894,5879,79837,7430,3845,10787,26999,5305,5605,5595,23396,7409,2768,2261,7454,998,10092,1445,3984,5597,9138,5296,60,6093,5594,2149,1072	WASF2,RHOA,NRAS,PPP1R12A,RAF1,RAC1,PIP4K2C,EZR,KRAS,NCKAP1,CYFIP2,PIP4K2A,MAP2K2,MAPK3,PIP5K1C,VAV1,GNA12,FGFR3,WAS,CDC42,ARPC5,CSK,LIMK1,MAPK6,ARHGEF1,PIK3R2,ACTB,ROCK1,MAPK1,F2R,CFL1
WP2361	Gastric Cancer Network 1	0.0616567311404131	-2.78617287219455	28	8	0.00955794504181601	837	5312	286826,3020,11065,1063,57122,22974,4605,56992	LIN9,H3F3A,UBE2C,CENPF,NUP107,TPX2,MYBL2,KIF15
WP2363	Gastric Cancer Network 2	0.0638223668087783	-2.75165157312903	33	9	0.010752688172043	837	5312	55593,5983,25909,29028,63922,55299,11065,6277,55215	OTUD5,RFC3,AHCTF1,ATAD2,CHTF18,BRIX1,UBE2C,S100A6,FANCI
WP1544	MicroRNAs in cardiomyocyte hypertrophy	0.0722273808214887	-2.62793606922037	102	22	0.026284348864994	837	5312	5170,7040,5530,387,5894,208,5879,4041,5532,1432,5605,50804,5595,805,3572,51564,5296,1855,6093,9020,5594,6774	PDPK1,TGFB1,PPP3CA,RHOA,RAF1,AKT2,RAC1,LRP5,PPP3CB,MAPK14,MAP2K2,MYEF2,MAPK3,CALM2,IL6ST,HDAC7,PIK3R2,DVL1,ROCK1,MAP3K14,MAPK1,STAT3
WP534	Glycolysis and Gluconeogenesis	0.0737952198748245	-2.60646132081731	49	12	0.014336917562724	837	5312	2806,4191,6513,3939,4190,2821,5315,5223,8050,51660,5214,3945	GOT2,MDH2,SLC2A1,LDHA,MDH1,GPI,PKM,PGAM1,PDHX,MPC1,PFKP,LDHB
WP2643	Nanoparticle-mediated activation of receptor signaling	0.0738918857084241	-2.6051522580251	29	8	0.00955794504181601	837	5312	4893,5894,3688,3845,1432,5594,5605,3265	NRAS,RAF1,ITGB1,KRAS,MAPK14,MAPK1,MAP2K2,HRAS
WP391	Mitochondrial Gene Expression	0.081536216221922	-2.50670798661766	20	6	0.00716845878136201	837	5312	4899,5530,1385,7978,2551,50804	NRF1,PPP3CA,CREB1,MTERF1,GABPA,MYEF2
WP2272	Pathogenic Escherichia coli infection	0.0817487774959756	-2.50410442349426	55	13	0.015531660692951	837	5312	387,7454,998,4690,10092,3688,9181,7430,7534,60,6093,10552,203068	RHOA,WAS,CDC42,NCK1,ARPC5,ITGB1,ARHGEF2,EZR,YWHAZ,ACTB,ROCK1,ARPC1A,TUBB
WP585	Interferon type I signaling pathways	0.0817487774959756	-2.50410442349426	55	13	0.015531660692951	837	5312	7409,1399,5906,3716,5296,5879,5781,6772,1385,6774,1432,27250,64223	VAV1,CRKL,RAP1A,JAK1,PIK3R2,RAC1,PTPN11,STAT1,CREB1,STAT3,MAPK14,PDCD4,MLST8
WP438	Non-homologous end joining	0.0832703775835589	-2.4856624042958	7	3	0.003584229390681	837	5312	7518,5591,7520	XRCC4,PRKDC,XRCC5
WP678	Arachidonate Epoxygenase / Epoxide Hydrolase	0.0832703775835589	-2.4856624042958	7	3	0.003584229390681	837	5312	9377,2053,1351	COX5A,EPHX2,COX8A
WP2637	Structural Pathway of Interleukin 1 (IL-1)	0.083841639548151	-2.47882550292133	50	12	0.014336917562724	837	5312	8569,23118,6294,10010,2002,9020,5594,1386,1432,54472,5605,5595	MKNK1,TAB2,SAFB,TANK,ELK1,MAP3K14,MAPK1,ATF2,MAPK14,TOLLIP,MAP2K2,MAPK3
WP1530	miRNA Regulation of DNA Damage Response	0.0857240174904139	-2.45662224187802	93	20	0.02389486260454	837	5312	5591,9874,10912,54205,672,891,355,1020,6118,5925,4193,4616,1869,3014,5371,1027,11200,1385,1017,9133	PRKDC,TLK1,GADD45G,CYCS,BRCA1,CCNB1,FAS,CDK5,RPA2,RB1,MDM2,GADD45B,E2F1,H2AFX,PML,CDKN1B,CHEK2,CREB1,CDK2,CCNB2
WP3915	Angiopoietin Like Protein 8 Regulatory Pathway	0.0870076693708877	-2.4417590105245	132	27	0.032258064516129	837	5312	5170,5564,7249,9322,5894,6195,208,6513,9448,5562,10211,8491,1432,2309,5605,6009,5595,4216,7248,6464,5296,5597,4217,9020,5594,3265,64223	PDPK1,PRKAB1,TSC2,TRIP10,RAF1,RPS6KA1,AKT2,SLC2A1,MAP4K4,PRKAA1,FLOT1,MAP4K3,MAPK14,FOXO3,MAP2K2,RHEB,MAPK3,MAP3K4,TSC1,SHC1,PIK3R2,MAPK6,MAP3K5,MAP3K14,MAPK1,HRAS,MLST8
WP241	One Carbon Metabolism	0.087489238924973	-2.43623947689628	30	8	0.00955794504181601	837	5312	27430,2618,10797,1788,471,191,4548,1786	MAT2B,GART,MTHFD2,DNMT3A,ATIC,AHCY,MTR,DNMT1
WP2870	Extracellular vesicle-mediated signaling in recipient cells	0.087489238924973	-2.43623947689628	30	8	0.00955794504181601	837	5312	7040,4087,4893,5894,8312,3845,4089,3265	TGFB1,SMAD2,NRAS,RAF1,AXIN1,KRAS,SMAD4,HRAS
WP244	Alpha 6 Beta 4 signaling pathway	0.087749861629256	-2.43326499351198	35	9	0.010752688172043	837	5312	387,6464,5879,5296,5781,1432,5594,3265,5595	RHOA,SHC1,RAC1,PIK3R2,PTPN11,MAPK14,MAPK1,HRAS,MAPK3
WP61	Notch Signaling Pathway	0.0990465709962571	-2.31216512535397	62	14	0.016726403823178	837	5312	9612,6868,51107,5296,8454,3516,4853,9794,6774,83464,5663,8650,3066,8819	NCOR2,ADAM17,APH1A,PIK3R2,CUL1,RBPJ,NOTCH2,MAML1,STAT3,APH1B,PSEN1,NUMB,HDAC2,SAP30
WP581	EPO Receptor Signaling	0.102108435981021	-2.28171993253306	26	7	0.00836320191158901	837	5312	6464,6774,5594,5894,5605,5595,6772	SHC1,STAT3,MAPK1,RAF1,MAP2K2,MAPK3,STAT1
WP1425	Bone Morphogenic Protein (BMP) Signalling and Regulation	0.106299436583249	-2.24149529389994	12	4	0.004778972520908	837	5312	4086,57154,4089,10140	SMAD1,SMURF1,SMAD4,TOB1
WP2203	Thymic Stromal LymphoPoietin (TSLP) Signaling Pathway	0.109943814389827	-2.20778582195568	47	11	0.013142174432497	837	5312	3716,6778,5781,6772,6774,5594,1432,4067,5605,5595,55361	JAK1,STAT6,PTPN11,STAT1,STAT3,MAPK1,MAPK14,LYN,MAP2K2,MAPK3,PI4K2A
WP405	Eukaryotic Transcription Initiation	0.113314186664117	-2.17759090551118	42	10	0.01194743130227	837	5312	5438,5436,5439,5440,6883,84172,2966,6878,51728,5430	POLR2I,POLR2G,POLR2J,POLR2K,TAF12,POLR1B,GTF2H2,TAF6,POLR3K,POLR2A
WP2636	Common Pathways Underlying Drug Addiction	0.113314186664117	-2.17759090551118	42	10	0.01194743130227	837	5312	2778,805,5906,5894,60,1385,5594,5566,5605,5595	GNAS,CALM2,RAP1A,RAF1,ACTB,CREB1,MAPK1,PRKACA,MAP2K2,MAPK3
WP3614	Photodynamic therapy-induced HIF-1 survival signaling	0.116326595434983	-2.15135356602218	37	9	0.010752688172043	837	5312	6566,578,4170,598,5315,332,6513,3939,54583	SLC16A1,BAK1,MCL1,BCL2L1,PKM,BIRC5,SLC2A1,LDHA,EGLN1
WP2253	Pilocytic astrocytoma	0.119451956517626	-2.12484102595872	4	2	0.002389486260454	837	5312	4763,5781	NF1,PTPN11
WP357	Fatty Acid Biosynthesis	0.119642368250226	-2.12324825061334	22	6	0.00716845878136201	837	5312	51703,1666,1891,2181,47,51102	ACSL5,DECR1,ECH1,ACSL3,ACLY,MECR
WP254	Apoptosis	0.121226524996936	-2.11009437618174	86	18	0.021505376344086	837	5312	578,330,839,331,4170,54205,598,3661,329,8772,3663,8837,355,3662,4193,332,596,1029	BAK1,BIRC3,CASP6,XIAP,MCL1,CYCS,BCL2L1,IRF3,BIRC2,FADD,IRF5,CFLAR,FAS,IRF4,MDM2,BIRC5,BCL2,CDKN2A
WP3859	TGF-B Signaling in Thyroid Cells for Epithelial-Mesenchymal Transition	0.140891355935101	-1.95976621089412	18	5	0.00597371565113501	837	5312	7040,4087,5594,4089,5595	TGFB1,SMAD2,MAPK1,SMAD4,MAPK3
WP3612	Photodynamic therapy-induced NFE2L2 (NRF2) survival signaling	0.1414754225843	-1.95562926896879	23	6	0.00716845878136201	837	5312	2730,9817,1728,1432,4835,140809	GCLM,KEAP1,NQO1,MAPK14,NQO2,SRXN1
WP1772	Apoptosis Modulation and Signaling	0.146397340428994	-1.92143084408856	94	19	0.022700119474313	837	5312	578,330,839,331,4170,54205,598,54472,329,8772,5595,8837,355,332,596,4217,9020,1029,27429	BAK1,BIRC3,CASP6,XIAP,MCL1,CYCS,BCL2L1,TOLLIP,BIRC2,FADD,MAPK3,CFLAR,FAS,BIRC5,BCL2,MAP3K5,MAP3K14,CDKN2A,HTRA2
WP3865	RIG-I-like Receptor Signaling	0.15344537055485	-1.87441066745034	61	13	0.015531660692951	837	5312	55593,23586,1540,5300,10010,80143,3661,57506,64343,1432,8772,9636,10521	OTUD5,DDX58,CYLD,PIN1,TANK,SIKE1,IRF3,MAVS,AZI2,MAPK14,FADD,ISG15,DDX17
WP143	Fatty Acid Beta Oxidation	0.155087219015434	-1.86376761699566	34	8	0.00955794504181601	837	5312	51703,1666,1384,2181,3032,38,1120,34	ACSL5,DECR1,CRAT,ACSL3,HADHB,ACAT1,CHKB,ACADM
WP1601	Fluoropyrimidine Activity	0.155087219015434	-1.86376761699566	34	8	0.00955794504181601	837	5312	7083,7371,6240,6241,83549,7517,2030,10057	TK1,UCK2,RRM1,RRM2,UCK1,XRCC3,SLC29A1,ABCC5
WP3658	Wnt/beta-catenin Signaling Pathway in Leukemia	0.164989953717357	-1.80187069349669	24	6	0.00716845878136201	837	5312	4041,1452,8323,6929,5371,8313	LRP5,CSNK1A1,FZD6,TCF3,PML,AXIN2
WP2516	ATM Signaling Pathway	0.167490235108962	-1.78683022727335	40	9	0.010752688172043	837	5312	4193,9874,3014,672,11200,891,1385,1017,1386	MDM2,TLK1,H2AFX,BRCA1,CHEK2,CCNB1,CREB1,CDK2,ATF2
WP35	G Protein Signaling Pathways	0.169123684762249	-1.77712496924131	96	19	0.022700119474313	837	5312	5530,387,4893,2788,5575,3845,5566,2783,8165,805,2778,2768,23683,10270,115,9138,2771,3265,113	PPP3CA,RHOA,NRAS,GNG7,PRKAR1B,KRAS,PRKACA,GNB2,AKAP1,CALM2,GNAS,GNA12,PRKD3,AKAP8,ADCY9,ARHGEF1,GNAI2,HRAS,ADCY7
WP236	Adipogenesis	0.173374733480486	-1.75229993759138	131	25	0.029868578255675	837	5312	7040,4282,9612,2971,4205,4209,1316,4000,355,5925,10555,5933,81029,3572,1874,6778,9663,4616,1869,6772,1855,8648,1385,6774,10499	TGFB1,MIF,NCOR2,GTF3A,MEF2A,MEF2D,KLF6,LMNA,FAS,RB1,AGPAT2,RBL1,WNT5B,IL6ST,E2F4,STAT6,LPIN2,GADD45B,E2F1,STAT1,DVL1,NCOA1,CREB1,STAT3,NCOA2
WP3303	Rac1/Pak1/p38/MMP-2 pathway	0.17376841432557	-1.75003181842301	68	14	0.016726403823178	837	5312	4893,332,4690,5879,5781,4436,3688,3845,6774,5594,3925,1432,3265,5595	NRAS,BIRC5,NCK1,RAC1,PTPN11,MSH2,ITGB1,KRAS,STAT3,MAPK1,STMN1,MAPK14,HRAS,MAPK3
WP311	Synthesis and Degradation of Ketone Bodies	0.178827434112175	-1.72133399338076	5	2	0.002389486260454	837	5312	38,622	ACAT1,BDH1
WP3668	Hypothesized Pathways in Pathogenesis of Cardiovascular Disease	0.190024812844464	-1.66060062143006	25	6	0.00716845878136201	837	5312	4087,6464,5594,1432,4089,5595	SMAD2,SHC1,MAPK1,MAPK14,SMAD4,MAPK3
WP497	Urea cycle and metabolism of amino groups	0.196605400856401	-1.6265566003524	20	5	0.00597371565113501	837	5312	6723,2746,5832,4942,4953	SRM,GLUD1,ALDH18A1,OAT,ODC1
WP2359	Parkin-Ubiquitin Proteasomal System pathway	0.203641268142245	-1.59139532259435	70	14	0.016726403823178	837	5312	5708,3308,5707,6477,5709,5714,6478,8454,25897,5715,5700,203068,3304,5704	PSMD2,HSPA4,PSMD1,SIAH1,PSMD3,PSMD8,SIAH2,CUL1,RNF19A,PSMD9,PSMC1,TUBB,HSPA1B,PSMC4
WP619	Type II interferon signaling (IFNG)	0.218056484642893	-1.52300114588818	37	8	0.00955794504181601	837	5312	3106,3662,3716,5781,6772,6890,5698,9636	HLA-B,IRF4,JAK1,PTPN11,STAT1,TAP1,PSMB9,ISG15
WP2864	Apoptosis-related network due to altered Notch3 in ovarian cancer	0.221680093486859	-1.50651995670764	54	11	0.013142174432497	837	5312	1728,332,10276,8312,8454,1027,308,5594,2149,2113,351	NQO1,BIRC5,NET1,AXIN1,CUL1,CDKN1B,ANXA5,MAPK1,F2R,ETS1,APP
WP3670	Simplified Interaction Map Between LOXL4 and Oxidative Stress Pathway	0.226911084166711	-1.48319703794122	21	5	0.00597371565113501	837	5312	7040,308,4899,1728,11140	TGFB1,ANXA5,NRF1,NQO1,CDC37
WP53	ID signaling pathway	0.236898422547373	-1.44012382656741	16	4	0.004778972520908	837	5312	5925,2002,5933,1017	RB1,ELK1,RBL1,CDK2
WP2018	RANKL/RANK (Receptor activator of NFKB (ligand)) Signaling Pathway	0.240546854570364	-1.42484038691317	55	11	0.013142174432497	837	5312	998,23118,208,5296,5879,6772,5594,7188,1432,4067,5595	CDC42,TAB2,AKT2,PIK3R2,RAC1,STAT1,MAPK1,TRAF5,MAPK14,LYN,MAPK3
WP3845	Canonical  and Non-canonical Notch signaling	0.24392081647365	-1.41091162900678	27	6	0.00716845878136201	837	5312	3516,4853,9794,5663,102,4236	RBPJ,NOTCH2,MAML1,PSEN1,ADAM10,MFAP1
WP2513	Nanoparticle triggered regulated necrosis	0.244352679280494	-1.40914269039671	11	3	0.003584229390681	837	5312	148022,2512,8772	TICAM1,FTL,FADD
WP3872	Regulation of Apoptosis by Parathyroid Hormone-related Protein	0.258460706497176	-1.35301160240134	22	5	0.00597371565113501	837	5312	83596,578,596,4170,598	BCL2L12,BAK1,BCL2,MCL1,BCL2L1
WP3874	Canonical and Non-Canonical TGF-B signaling	0.274090317614702	-1.29429760057786	17	4	0.004778972520908	837	5312	7040,4087,1432,4089	TGFB1,SMAD2,MAPK14,SMAD4
WP195	IL-1 signaling pathway	0.279926023120466	-1.27322991386188	57	11	0.013142174432497	837	5312	23118,5296,5781,7335,9020,5594,1386,1432,54472,5605,5595	TAB2,PIK3R2,PTPN11,UBE2V1,MAP3K14,MAPK1,ATF2,MAPK14,TOLLIP,MAP2K2,MAPK3
WP1438	Influenza A virus infection	0.290332933123183	-1.23672696924927	2	1	0.001194743130227	837	5312	596	BCL2
WP1273	Folic Acid Network	0.290332933123183	-1.23672696924927	2	1	0.001194743130227	837	5312	7295	TXN
WP1311	Folic Acid Network	0.290332933123183	-1.23672696924927	2	1	0.001194743130227	837	5312	7295	TXN
WP2366	Butyrate-induced histone acetylation	0.290332933123183	-1.23672696924927	2	1	0.001194743130227	837	5312	47	ACLY
WP3849	MAPK  and NFkB Signalling Pathways Inhibited by Yersinia YopJ	0.290370426848974	-1.23659783713664	12	3	0.003584229390681	837	5312	9020,5594,5894	MAP3K14,MAPK1,RAF1
WP560	TGF-beta Receptor Signaling	0.300310511756869	-1.20293830042011	58	11	0.013142174432497	837	5312	7040,2280,4087,3716,7030,6772,4086,6774,3265,4089,5595	TGFB1,FKBP1A,SMAD2,JAK1,TFE3,STAT1,SMAD1,STAT3,HRAS,SMAD4,MAPK3
WP1310	Selenium Micronutrient Network	0.304608667812644	-1.18872738254826	7	2	0.002389486260454	837	5312	6415,7295	SELENOW,TXN
WP1272	Selenium Micronutrient Network	0.304608667812644	-1.18872738254826	7	2	0.002389486260454	837	5312	6415,7295	SELENOW,TXN
WP134	Pentose Phosphate Pathway	0.304608667812644	-1.18872738254826	7	2	0.002389486260454	837	5312	6888,7086	TALDO1,TKT
WP3595	mir-124 predicted interactions with cell cycle and differentiation	0.304608667812644	-1.18872738254826	7	2	0.002389486260454	837	5312	6794,5562	STK11,PRKAA1
WP3664	Regulation of Wnt/B-catenin Signaling by Small Molecule Compounds	0.312147163810011	-1.16428052349993	18	4	0.004778972520908	837	5312	154141,1452,8312,1856	MBOAT1,CSNK1A1,AXIN1,DVL2
WP1991	SRF and miRs in Smooth Muscle Differentiation and Proliferation	0.336902183977538	-1.08796264602152	13	3	0.003584229390681	837	5312	4205,4209,2002	MEF2A,MEF2D,ELK1
WP1434	Osteopontin Signaling	0.336902183977538	-1.08796264602152	13	3	0.003584229390681	837	5312	9020,5594,5595	MAP3K14,MAPK1,MAPK3
WP3286	Copper homeostasis	0.341633454761155	-1.07401688637961	54	10	0.01194743130227	837	5312	1317,6868,4193,5728,102,331,8754,351,2309,5621	SLC31A1,ADAM17,MDM2,PTEN,ADAM10,XIAP,ADAM9,APP,FOXO3,PRNP
WP384	Apoptosis Modulation by HSP70	0.350629579570462	-1.04802494162694	19	4	0.004778972520908	837	5312	54205,839,8772,355	CYCS,CASP6,FADD,FAS
WP3414	Initiation of transcription and translation elongation at the HIV-1 LTR	0.36337089023797	-1.01233123014168	37	7	0.00836320191158901	837	5312	4773,5530,4775,5532,51564,3066,5534	NFATC2,PPP3CA,NFATC3,PPP3CB,HDAC7,HDAC2,PPP3R1
WP1403	AMP-activated Protein Kinase (AMPK) Signaling	0.382997131550112	-0.959727779254833	68	12	0.014336917562724	837	5312	5564,7248,890,7249,208,5562,5296,5209,51719,6794,891,29904	PRKAB1,TSC1,CCNA2,TSC2,AKT2,PRKAA1,PIK3R2,PFKFB3,CAB39,STK11,CCNB1,EEF2K
WP3680	Association Between Physico-Chemical Features and Toxicity Associated Pathways	0.382997131550112	-0.959727779254833	68	12	0.014336917562724	837	5312	5515,387,6464,4690,5894,8312,10096,1027,1855,2002,5594,8323	PPP2CA,RHOA,SHC1,NCK1,RAF1,AXIN1,ACTR3,CDKN1B,DVL1,ELK1,MAPK1,FZD6
WP2436	Dopamine metabolism	0.383239157370305	-0.959096052901639	14	3	0.003584229390681	837	5312	5515,1728,5566	PPP2CA,NQO1,PRKACA
WP2355	Corticotropin-releasing hormone signaling pathway	0.392580085075101	-0.935014724164779	93	16	0.019115890083632	837	5312	7040,2778,387,5894,596,2002,4217,1385,5594,1432,409,2771,2783,10155,10499,5595	TGFB1,GNAS,RHOA,RAF1,BCL2,ELK1,MAP3K5,CREB1,MAPK1,MAPK14,ARRB2,GNAI2,GNB2,TRIM28,NCOA2,MAPK3
WP2369	Histone Modifications	0.403572300899392	-0.907399622938628	69	12	0.014336917562724	837	5312	55870,84787,79723,55904,387893,84193,79813,9757,2145,3020,58508,84444	ASH1L,KMT5C,SUV39H2,KMT2E,KMT5A,SETD3,EHMT1,KMT2B,EZH1,H3F3A,KMT2C,DOT1L
WP561	Heme Biosynthesis	0.426638001406174	-0.851819397197823	9	2	0.002389486260454	837	5312	1371,7389	CPOX,UROD
WP3300	Dual hijack model of Vif in HIV infection	0.426638001406174	-0.851819397197823	9	2	0.002389486260454	837	5312	9978,865	RBX1,CBFB
WP3	Transcriptional activation by NRF2	0.428788979461922	-0.84679037043753	15	3	0.003584229390681	837	5312	2730,9817,1728	GCLM,KEAP1,NQO1
WP197	Cholesterol Biosynthesis	0.428788979461922	-0.84679037043753	15	3	0.003584229390681	837	5312	10654,50814,2222	PMVK,NSDHL,FDFT1
WP704	Methylation Pathways	0.483379431441733	-0.726953361386882	10	2	0.002389486260454	837	5312	27430,4144	MAT2B,MAT2A
WP2113	Type III interferon signaling	0.483379431441733	-0.726953361386882	10	2	0.002389486260454	837	5312	3716,6772	JAK1,STAT1
WP2583	T-Cell Receptor and Co-stimulatory Signaling	0.490410310543128	-0.712512869819473	29	5	0.00597371565113501	837	5312	805,4773,5530,1452,5728	CALM2,NFATC2,PPP3CA,CSNK1A1,PTEN
WP1941	Peroxisomal beta-oxidation of tetracosanoyl-CoA	0.496443625264761	-0.700285346223991	4	1	0.001194743130227	837	5312	51	ACOX1
WP690	Polyol Pathway	0.496443625264761	-0.700285346223991	4	1	0.001194743130227	837	5312	231	AKR1B1
WP733	Serotonin Receptor 2 and STAT3 Signaling	0.496443625264761	-0.700285346223991	4	1	0.001194743130227	837	5312	6774	STAT3
WP3302	eIF5A regulation in response to inhibition of the nuclear export system	0.496443625264761	-0.700285346223991	4	1	0.001194743130227	837	5312	1984	EIF5A
WP3594	Circadian rythm related genes	0.500837004218894	-0.691474571712549	207	33	0.039426523297491	837	5312	6096,9500,5562,1660,8454,9967,56339,5936,1390,9456,85457,79723,5728,9112,8914,191,1408,1385,10499,7071,55269,5591,355,6233,4669,4783,406,8473,5371,1655,26224,1453,3066	RORB,MAGED1,PRKAA1,DHX9,CUL1,THRAP3,METTL3,RBM4,CREM,HOMER1,CIPC,SUV39H2,PTEN,MTA1,TIMELESS,AHCY,CRY2,CREB1,NCOA2,KLF10,PSPC1,PRKDC,FAS,RPS27A,NAGLU,NFIL3,ARNTL,OGT,PML,DDX5,FBXL3,CSNK1D,HDAC2
WP2572	Primary Focal Segmental Glomerulosclerosis FSGS	0.506106140345265	-0.681008868163772	74	12	0.014336917562724	837	5312	1514,7040,64423,950,5111,375790,4690,3688,4288,4627,1027,4041	CTSL,TGFB1,INF2,SCARB2,PCNA,AGRN,NCK1,ITGB1,MKI67,MYH9,CDKN1B,LRP5
WP306	Focal Adhesion	0.50954463647319	-0.674237821769722	195	31	0.037037037037037	837	5312	5170,387,330,4659,5894,208,5879,331,2002,3693,5605,329,388,23396,7409,5906,7408,3696,6464,998,5728,5597,53918,5296,3688,60,596,6093,5594,3265,823	PDPK1,RHOA,BIRC3,PPP1R12A,RAF1,AKT2,RAC1,XIAP,ELK1,ITGB5,MAP2K2,BIRC2,RHOB,PIP5K1C,VAV1,RAP1A,VASP,ITGB8,SHC1,CDC42,PTEN,MAPK6,PELO,PIK3R2,ITGB1,ACTB,BCL2,ROCK1,MAPK1,HRAS,CAPN1
WP500	Glycogen Metabolism	0.510424512708583	-0.67251252163813	36	6	0.00716845878136201	837	5312	5515,805,2992,5525,7360,5261	PPP2CA,CALM2,GYG1,PPP2R5A,UGP2,PHKG2
WP368	Mitochondrial LC-Fatty Acid Beta-Oxidation	0.515710222408631	-0.662210255727598	17	3	0.003584229390681	837	5312	34,80221,2181	ACADM,ACSF2,ACSL3
WP2853	Endoderm Differentiation	0.522026531244146	-0.650036866252891	145	23	0.027479091995221	837	5312	7040,55809,9682,9044,26610,11169,23168,79577,351,10459,84295,55832,54623,3087,4087,79035,6478,6772,10128,9646,27245,4089,26986	TGFB1,TRERF1,KDM4A,BTAF1,ELP4,WDHD1,RTF1,CDC73,APP,MAD2L2,PHF6,CAND1,PAF1,HHEX,SMAD2,NABP2,SIAH2,STAT1,LRPPRC,CTR9,AHDC1,SMAD4,PABPC1
WP1449	Regulation of toll-like receptor signaling pathway	0.522026531244146	-0.650036866252891	145	23	0.027479091995221	837	5312	7874,5347,55593,51014,1540,10906,7128,10771,208,5879,3661,54472,1432,5605,3663,8772,5595,23118,5296,6772,148022,5594,64223	USP7,PLK1,OTUD5,TMED7,CYLD,TRAFD1,TNFAIP3,ZMYND11,AKT2,RAC1,IRF3,TOLLIP,MAPK14,MAP2K2,IRF5,FADD,MAPK3,TAB2,PIK3R2,STAT1,TICAM1,MAPK1,MLST8
WP1539	Angiogenesis	0.536896842016152	-0.621949303455524	24	4	0.004778972520908	837	5312	7077,4086,5594,1432	TIMP2,SMAD1,MAPK1,MAPK14
WP2112	IL17 signaling pathway	0.553156278346556	-0.592114716395593	31	5	0.00597371565113501	837	5312	9020,3716,6774,5594,5595	MAP3K14,JAK1,STAT3,MAPK1,MAPK3
WP2059	Alzheimers Disease	0.56493002191461	-0.571053410524753	148	23	0.027479091995221	837	5312	5530,6868,51107,102,54205,5532,5663,351,8772,5595,355,1020,805,824,3416,488,81671,5534,22926,5594,54480,823,11261	PPP3CA,ADAM17,APH1A,ADAM10,CYCS,PPP3CB,PSEN1,APP,FADD,MAPK3,FAS,CDK5,CALM2,CAPN2,IDE,ATP2A2,VMP1,PPP3R1,ATF6,MAPK1,CHPF2,CAPN1,CHP1
WP2011	SREBF and miR33 in cholesterol and lipid homeostasis	0.5950090693571	-0.519178630935699	19	3	0.003584229390681	837	5312	19,51586,5562	ABCA1,MED15,PRKAA1
WP2197	Endothelin Pathways	0.611875570947944	-0.491226332585734	33	5	0.00597371565113501	837	5312	2778,805,488,5594,5894	GNAS,CALM2,ATP2A2,MAPK1,RAF1
WP3892	Development of pulmonary dendritic cells and macrophage subsets	0.630961611553857	-0.460510255765676	13	2	0.002389486260454	837	5312	3662,6774	IRF4,STAT3
WP186	Homologous recombination	0.630961611553857	-0.460510255765676	13	2	0.002389486260454	837	5312	25788,6117	RAD54B,RPA1
WP2881	Estrogen Receptor Pathway	0.630961611553857	-0.460510255765676	13	2	0.002389486260454	837	5312	6774,51	STAT3,ACOX1
WP516	Hypertrophy Model	0.631339677314665	-0.459911245409833	20	3	0.003584229390681	837	5312	3475,102,9948	IFRD1,ADAM10,WDR1
WP1742	TP53 Network	0.631339677314665	-0.459911245409833	20	3	0.003584229390681	837	5312	596,4193,1029	BCL2,MDM2,CDKN2A
WP1422	Sphingolipid Metabolism	0.631339677314665	-0.459911245409833	20	3	0.003584229390681	837	5312	427,253782,64781	ASAH1,CERS6,CERK
WP3891	Benzene metabolism	0.642743376398564	-0.442009737986764	6	1	0.001194743130227	837	5312	1728	NQO1
WP2873	Aryl Hydrocarbon Receptor Pathway	0.649666084313941	-0.431296764530044	48	7	0.00836320191158901	837	5312	7040,1027,10728,8648,1728,51426,11140	TGFB1,CDKN1B,PTGES3,NCOA1,NQO1,POLK,CDC37
WP3863	T-Cell antigen Receptor (TCR) pathway during Staphylococcus aureus infection	0.659886184048277	-0.415687907244304	62	9	0.010752688172043	837	5312	805,4690,10598,5894,4773,9020,5605,11261,5595	CALM2,NCK1,AHSA1,RAF1,NFATC2,MAP3K14,MAP2K2,CHP1,MAPK3
WP176	Folate Metabolism	0.664862084314944	-0.408175651842582	69	10	0.01194743130227	837	5312	80308,847,6573,2618,10797,191,949,4548,19,2879	FLAD1,CAT,SLC19A1,GART,MTHFD2,AHCY,SCARB1,MTR,ABCA1,GPX4
WP2012	miRs in Muscle Cell Differentiation	0.690911852694531	-0.369743028193042	36	5	0.00597371565113501	837	5312	4205,23683,4209,5566,5575	MEF2A,PRKD3,MEF2D,PRKACA,PRKAR1B
WP3613	Photodynamic therapy-induced unfolded protein response	0.692197317923258	-0.367884222501982	29	4	0.004778972520908	837	5312	22926,83939,10130,4189	ATF6,EIF2A,PDIA6,DNAJB9
WP3645	NAD+ biosynthetic pathways	0.697006004775121	-0.360961253086383	22	3	0.003584229390681	837	5312	55191,22933,143	NADSYN1,SIRT2,PARP4
WP528	Acetylcholine Synthesis	0.69909916115868	-0.357962685352372	7	1	0.001194743130227	837	5312	1119	CHKA
WP2805	RNA interference	0.69909916115868	-0.357962685352372	7	1	0.001194743130227	837	5312	54487	DGCR8
WP2435	Quercetin and Nf-kB/ AP-1 Induced Cell Apoptosis	0.709704026902691	-0.342907259375862	15	2	0.002389486260454	837	5312	9817,7975	KEAP1,MAFK
WP2431	Spinal Cord Injury	0.71002491789046	-0.342455213942247	119	17	0.020310633213859	837	5312	7040,4282,2280,5925,5530,387,998,7832,389,5879,1869,1027,5594,1017,2309,388,5595	TGFB1,MIF,FKBP1A,RB1,PPP3CA,RHOA,CDC42,BTG2,RHOC,RAC1,E2F1,CDKN1B,MAPK1,CDK2,FOXO3,RHOB,MAPK3
WP15	Selenium Micronutrient Network	0.737554526854157	-0.304415258783697	87	12	0.014336917562724	837	5312	6415,80308,847,22928,7295,10935,25824,949,19,4548,5052,2879	SELENOW,FLAD1,CAT,SEPHS2,TXN,PRDX3,PRDX5,SCARB1,ABCA1,MTR,PRDX1,GPX4
WP3850	Factors and pathways affecting insulin-like growth factor (IGF1)-Akt signaling	0.742819203837928	-0.297302596528773	31	4	0.004778972520908	837	5312	5564,4087,5728,3688	PRKAB1,SMAD2,PTEN,ITGB1
WP2291	Deregulation of Rab and Rab Effector Genes in Bladder Cancer	0.743508685658182	-0.296374831027524	16	2	0.002389486260454	837	5312	9648,94120	GCC2,SYTL3
WP47	Hedgehog Signaling Pathway	0.743508685658182	-0.296374831027524	16	2	0.002389486260454	837	5312	156,406	GRK2,ARNTL
WP2338	miRNA Biogenesis	0.746573996627441	-0.292260542163327	8	1	0.001194743130227	837	5312	54487	DGCR8
WP1589	Folate-Alcohol and Cancer Pathway	0.746573996627441	-0.292260542163327	8	1	0.001194743130227	837	5312	1385	CREB1
WP3635	Insulin signalling in human adipocytes (diabetic condition)	0.746573996627441	-0.292260542163327	8	1	0.001194743130227	837	5312	208	AKT2
WP136	Phase I biotransformations, non P450	0.746573996627441	-0.292260542163327	8	1	0.001194743130227	837	5312	5445	PON2
WP3634	Insulin signalling in human adipocytes (normal condition)	0.746573996627441	-0.292260542163327	8	1	0.001194743130227	837	5312	208	AKT2
WP3655	Hypothetical Craniofacial Development Pathway	0.746573996627441	-0.292260542163327	8	1	0.001194743130227	837	5312	387	RHOA
WP2485	NAD Biosynthesis II (from tryptophan)	0.746573996627441	-0.292260542163327	8	1	0.001194743130227	837	5312	55191	NADSYN1
WP28	Selenium Metabolism and Selenoproteins	0.753817965734773	-0.282604364876771	46	6	0.00716845878136201	837	5312	6415,22928,6670,79048,2879,1390	SELENOW,SEPHS2,SP3,SECISBP2,GPX4,CREM
WP465	Tryptophan metabolism	0.753817965734773	-0.282604364876771	46	6	0.00716845878136201	837	5312	38,847,4967,4193,64320,223	ACAT1,CAT,OGDH,MDM2,RNF25,ALDH9A1
WP1591	Heart Development	0.753817965734773	-0.282604364876771	46	6	0.00716845878136201	837	5312	4773,4775,4086,5594,4089,5781	NFATC2,NFATC3,SMAD1,MAPK1,SMAD4,PTPN11
WP3858	Toll-like Receptor Signaling	0.765640116883348	-0.267043040943266	32	4	0.004778972520908	837	5312	148022,3661,5594,54472	TICAM1,IRF3,MAPK1,TOLLIP
WP75	Toll-like Receptor Signaling Pathway	0.767860622804151	-0.264147043027846	103	14	0.016726403823178	837	5312	23118,208,5879,5296,6772,148022,3661,5594,1432,54472,5605,8772,3663,5595	TAB2,AKT2,RAC1,PIK3R2,STAT1,TICAM1,IRF3,MAPK1,MAPK14,TOLLIP,MAP2K2,FADD,IRF5,MAPK3
WP673	ErbB Signaling Pathway	0.768891419402114	-0.26280551658214	54	7	0.00836320191158901	837	5312	1027,3845,4193,2002,5594,4690,3265	CDKN1B,KRAS,MDM2,ELK1,MAPK1,NCK1,HRAS
WP289	Myometrial Relaxation and Contraction Pathways	0.771048001573431	-0.260004648506704	158	22	0.026284348864994	837	5312	2551,2788,5575,5997,5566,2783,5996,805,2778,2114,488,115,27297,60,7534,1265,1385,7533,409,1386,818,113	GABPA,GNG7,PRKAR1B,RGS2,PRKACA,GNB2,RGS1,CALM2,GNAS,ETS2,ATP2A2,ADCY9,CRCP,ACTB,YWHAZ,CNN2,CREB1,YWHAH,ARRB2,ATF2,CAMK2G,ADCY7
WP3678	Amplification and Expansion of Oncogenic Pathways as Metastatic Traits	0.773881814091518	-0.256336112023673	17	2	0.002389486260454	837	5312	9595,7428	CYTIP,VHL
WP3875	ATR Signaling	0.786565996031696	-0.240078648965746	9	1	0.001194743130227	837	5312	6117	RPA1
WP2942	DDX1 as a regulatory component of the Drosha microprocessor	0.786565996031696	-0.240078648965746	9	1	0.001194743130227	837	5312	54487	DGCR8
WP288	NLR Proteins	0.786565996031696	-0.240078648965746	9	1	0.001194743130227	837	5312	55914	ERBIN
WP3674	Tgif disruption of Shh signaling	0.786565996031696	-0.240078648965746	9	1	0.001194743130227	837	5312	4087	SMAD2
WP428	Wnt Signaling Pathway	0.795142604510713	-0.229233803670855	70	9	0.010752688172043	837	5312	387,81029,8312,5879,26190,4041,1855,1856,8323	RHOA,WNT5B,AXIN1,RAC1,FBXW2,LRP5,DVL1,DVL2,FZD6
WP1433	Nucleotide-binding Oligomerization Domain (NOD) pathway	0.796575951956887	-0.227432797044668	41	5	0.00597371565113501	837	5312	55914,10980,5879,9744,331	ERBIN,COPS6,RAC1,ACAP1,XIAP
WP325	Triacylglyceride Synthesis	0.801039435936241	-0.221845099747123	26	3	0.003584229390681	837	5312	56894,10555,10554	AGPAT3,AGPAT2,AGPAT1
WP3656	Interleukin-1 Induced Activation of NF-kappa-B	0.820253392086432	-0.198141971719507	10	1	0.001194743130227	837	5312	7335	UBE2V1
WP1531	Vitamin D Metabolism	0.820253392086432	-0.198141971719507	10	1	0.001194743130227	837	5312	6257	RXRB
WP3617	Photodynamic therapy-induced NF-kB survival signaling	0.824646302958493	-0.192800708262406	35	4	0.004778972520908	837	5312	330,332,329,8837	BIRC3,BIRC5,BIRC2,CFLAR
WP536	Calcium Regulation in the Cardiac Cell	0.834510992078307	-0.180909363913903	151	20	0.02389486260454	837	5312	309,2788,5575,154,5997,5566,2783,5996,805,2280,2778,782,488,115,7534,2771,409,7533,818,113	ANXA6,GNG7,PRKAR1B,ADRB2,RGS2,PRKACA,GNB2,RGS1,CALM2,FKBP1A,GNAS,CACNB1,ATP2A2,ADCY9,YWHAZ,GNAI2,ARRB2,YWHAH,CAMK2G,ADCY7
WP2064	Neural Crest Differentiation	0.83648235287885	-0.178549855156929	102	13	0.015531660692951	837	5312	2261,51564,8312,8313,3688,3516,1855,4853,4086,2113,1856,3066,388	FGFR3,HDAC7,AXIN1,AXIN2,ITGB1,RBPJ,DVL1,NOTCH2,SMAD1,ETS1,DVL2,HDAC2,RHOB
WP3298	Melatonin metabolism and effects	0.841363109240219	-0.172731953283921	36	4	0.004778972520908	837	5312	805,1408,406,1453	CALM2,CRY2,ARNTL,CSNK1D
WP3630	NAD metabolism, sirtuins and aging	0.848629082553831	-0.164133075585236	11	1	0.001194743130227	837	5312	2309	FOXO3
WP2267	Synaptic Vesicle Pathway	0.849880481056366	-0.162659549906283	52	6	0.00716845878136201	837	5312	163,4905,1175,440279,11315,1785	AP2B1,NSF,AP2S1,UNC13C,PARK7,DNM2
WP3527	Preimplantation Embryo	0.855439860860063	-0.156139485186814	60	7	0.00836320191158901	837	5312	6597,8570,3662,476,3182,4603,4084	SMARCA4,KHSRP,IRF4,ATP1A1,HNRNPAB,MYBL1,MXD1
WP1602	Nicotine Activity on Dopaminergic Neurons	0.865964353983705	-0.143911532948502	21	2	0.002389486260454	837	5312	1020,5566	CDK5,PRKACA
WP3672	LncRNA-mediated mechanisms of therapeutic resistance	0.872529753737945	-0.136358523781624	12	1	0.001194743130227	837	5312	598	BCL2L1
WP106	Alanine and aspartate metabolism	0.872529753737945	-0.136358523781624	12	1	0.001194743130227	837	5312	2806	GOT2
WP2007	Iron metabolism in placenta	0.872529753737945	-0.136358523781624	12	1	0.001194743130227	837	5312	7037	TFRC
WP3301	MFAP5-mediated ovarian cancer cell motility and invasiveness	0.872529753737945	-0.136358523781624	12	1	0.001194743130227	837	5312	5594	MAPK1
WP3851	TLR4 Signaling and Tolerance	0.873339926753719	-0.135430421205605	30	3	0.003584229390681	837	5312	148022,3661,23118	TICAM1,IRF3,TAB2
WP98	Prostaglandin Synthesis and Regulation	0.873339926753719	-0.135430421205605	30	3	0.003584229390681	837	5312	308,309,6277	ANXA5,ANXA6,S100A6
WP167	Eicosanoid Synthesis	0.882860188911052	-0.124588427368791	22	2	0.002389486260454	837	5312	50640,4048	PNPLA8,LTA4H
WP100	Glutathione metabolism	0.882860188911052	-0.124588427368791	22	2	0.002389486260454	837	5312	2730,2879	GCLM,GPX4
WP1584	Type II diabetes mellitus	0.882860188911052	-0.124588427368791	22	2	0.002389486260454	837	5312	5594,122809	MAPK1,SOCS4
WP1424	Globo Sphingolipid Metabolism	0.882860188911052	-0.124588427368791	22	2	0.002389486260454	837	5312	6483,2590	ST3GAL2,GALNT2
WP408	Oxidative Stress	0.887324289926014	-0.11954476041578	31	3	0.003584229390681	837	5312	847,1728,1432	CAT,NQO1,MAPK14
WP3871	Valproic acid pathway	0.892660432264828	-0.113549025443501	13	1	0.001194743130227	837	5312	3032	HADHB
WP3876	BMP2-WNT4-FOXO1 Pathway in Human Primary Endometrial Stromal Cell Differentiation	0.892660432264828	-0.113549025443501	13	1	0.001194743130227	837	5312	4086	SMAD1
WP1423	Ganglio Sphingolipid Metabolism	0.892660432264828	-0.113549025443501	13	1	0.001194743130227	837	5312	6483	ST3GAL2
WP229	Irinotecan Pathway	0.909615181875505	-0.0947336459688446	14	1	0.001194743130227	837	5312	4363	ABCC1
WP706	Sudden Infant Death Syndrome (SIDS) Susceptibility Pathways	0.909953866466372	-0.0943613769471368	162	20	0.02389486260454	837	5312	4152,6670,5454,10522,2305,4204,6929,5575,10664,3784,5566,1390,55536,3032,4904,7534,34,1385,7533,23171	MBD1,SP3,POU3F2,DEAF1,FOXM1,MECP2,TCF3,PRKAR1B,CTCF,KCNQ1,PRKACA,CREM,CDCA7L,HADHB,YBX1,YWHAZ,ACADM,CREB1,YWHAH,GPD1L
WP262	EBV LMP1 signaling	0.910890385905229	-0.0933327117878631	24	2	0.002389486260454	837	5312	9020,5594	MAP3K14,MAPK1
WP430	Statin Pathway	0.911218636630361	-0.0929724142155192	33	3	0.003584229390681	837	5312	949,19,2222	SCARB1,ABCA1,FDFT1
WP2857	Mesodermal Commitment Pathway	0.916250041537142	-0.0874659804474246	156	19	0.022700119474313	837	5312	55809,6169,11169,26610,23499,5566,2132,10155,84295,5515,4087,57045,8030,8312,79035,8313,27245,4086,4089	TRERF1,RPL38,WDHD1,ELP4,MACF1,PRKACA,EXT2,TRIM28,PHF6,PPP2CA,SMAD2,TWSG1,CCDC6,AXIN1,NABP2,AXIN2,AHDC1,SMAD1,SMAD4
WP2895	Differentiation of white and brown adipocyte	0.922422303634713	-0.0807521303166785	25	2	0.002389486260454	837	5312	4086,1054	SMAD1,CEBPG
WP2865	IL1 and megakaryocytes in obesity	0.922422303634713	-0.0807521303166785	25	2	0.002389486260454	837	5312	7077,2149	TIMP2,F2R
WP2858	Ectoderm Differentiation	0.924051654365985	-0.0789873059094765	143	17	0.020310633213859	837	5312	1952,4204,6929,6016,4061,8675,55843,152789,7343,56913,54521,6238,8473,3148,7026,57154,4089	CELSR2,MECP2,TCF3,RIT1,LY6E,STX16,ARHGAP15,JAKMIP1,UBTF,C1GALT1,WDR44,RRBP1,OGT,HMGB2,NR2F2,SMURF1,SMAD4
WP399	Wnt Signaling Pathway and Pluripotency	0.924523880012889	-0.0784763982961353	106	12	0.014336917562724	837	5312	5515,387,81029,8312,8313,85409,26190,4041,29127,1855,8323,1856	PPP2CA,RHOA,WNT5B,AXIN1,AXIN2,NKD2,FBXW2,LRP5,RACGAP1,DVL1,FZD6,DVL2
WP2118	Arrhythmogenic Right Ventricular Cardiomyopathy	0.928592796989954	-0.0740849602754696	76	8	0.00955794504181601	837	5312	782,3696,488,3688,60,3693,6443,4000	CACNB1,ITGB8,ATP2A2,ITGB1,ACTB,ITGB5,SGCB,LMNA
WP2878	PPAR Alpha Pathway	0.932537542605188	-0.0698458681081638	26	2	0.002389486260454	837	5312	34,1622	ACADM,DBI
WP716	Vitamin A and Carotenoid Metabolism	0.932548054919489	-0.0698345953662427	44	4	0.004778972520908	837	5312	949,5594,157506,6257	SCARB1,MAPK1,RDH10,RXRB
WP12	Osteoclast Signaling	0.935920274389555	-0.0662249830665421	16	1	0.001194743130227	837	5312	9550	ATP6V1G1
WP3644	NAD+ metabolism	0.935920274389555	-0.0662249830665421	16	1	0.001194743130227	837	5312	22933	SIRT2
WP3529	Zinc homeostasis	0.945732387636992	-0.0557956382837009	37	3	0.003584229390681	837	5312	10463,55334,91252	SLC30A9,SLC39A9,SLC39A13
WP554	ACE Inhibitor Pathway	0.946047678160051	-0.0554623114539288	17	1	0.001194743130227	837	5312	7040	TGFB1
WP2249	Metastatic brain tumor	0.949141056091182	-0.0521978548620143	28	2	0.002389486260454	837	5312	998,1871	CDC42,E2F3
WP2328	Allograft Rejection	0.950033408683932	-0.0512581279701782	80	8	0.00955794504181601	837	5312	7040,3106,3035,2551,3133,3105,6772,355	TGFB1,HLA-B,HARS,GABPA,HLA-E,HLA-A,STAT1,FAS
WP2029	Cell Differentiation - Index	0.952155717518478	-0.0490266887447618	38	3	0.003584229390681	837	5312	4205,4209,6774	MEF2A,MEF2D,STAT3
WP3413	NOTCH1 regulation of human endothelial cell calcification	0.95457611884486	-0.046487891646735	18	1	0.001194743130227	837	5312	2261	FGFR3
WP474	Endochondral Ossification	0.956273893971152	-0.0447109069941906	65	6	0.00716845878136201	837	5312	7040,51719,805,2261,5566,6772	TGFB1,CAB39,CALM2,FGFR3,PRKACA,STAT1
WP3877	Simplified Depiction of MYD88 Distinct Input-Output Pathway	0.961757794050517	-0.0389926333529188	19	1	0.001194743130227	837	5312	7335	UBE2V1
WP3287	Overview of nanoparticle effects	0.961757794050517	-0.0389926333529188	19	1	0.001194743130227	837	5312	596	BCL2
WP2879	Farnesoid X Receptor  Pathway	0.961757794050517	-0.0389926333529188	19	1	0.001194743130227	837	5312	2289	FKBP5
WP1992	TarBasePathway	0.961757794050517	-0.0389926333529188	19	1	0.001194743130227	837	5312	3784	KCNQ1
WP247	Small Ligand GPCRs	0.961757794050517	-0.0389926333529188	19	1	0.001194743130227	837	5312	9294	S1PR2
WP697	Estrogen metabolism	0.961757794050517	-0.0389926333529188	19	1	0.001194743130227	837	5312	1728	NQO1
WP2855	Dopaminergic Neurogenesis	0.961801491139849	-0.0389471997760323	30	2	0.002389486260454	837	5312	7040,6774	TGFB1,STAT3
WP1545	miRNAs involved in DNA damage response	0.966282672648291	-0.0342988657859033	50	4	0.004778972520908	837	5312	1027,1385,1869,3014	CDKN1B,CREB1,E2F1,H2AFX
WP34	Ovarian Infertility Genes	0.971406219313876	-0.0290105466678094	32	2	0.002389486260454	837	5312	1027,7784	CDKN1B,ZP3
WP727	Monoamine Transport	0.971406219313876	-0.0290105466678094	32	2	0.002389486260454	837	5312	7249,1432	TSC2,MAPK14
WP2875	Constitutive Androstane Receptor Pathway	0.971406219313876	-0.0290105466678094	32	2	0.002389486260454	837	5312	8648,10499	NCOA1,NCOA2
WP1533	Vitamin B12 Metabolism	0.976484663307435	-0.0237962345670968	53	4	0.004778972520908	837	5312	949,4594,19,4548	SCARB1,MUT,ABCA1,MTR
WP3599	Transcription factor regulation in adipogenesis	0.977184680857891	-0.0230796162892868	22	1	0.001194743130227	837	5312	1385	CREB1
WP698	Glucuronidation	0.988546927560019	-0.011519163992966	26	1	0.001194743130227	837	5312	7360	UGP2
WP530	Cytokines and Inflammatory Response	0.988546927560019	-0.011519163992966	26	1	0.001194743130227	837	5312	7040	TGFB1
WP170	Nuclear Receptors	0.989848673455045	-0.0102032026329463	39	2	0.002389486260454	837	5312	7026,6257	NR2F2,RXRB
WP3624	Lung fibrosis	0.99329759580874	-0.00672496617174971	63	4	0.004778972520908	837	5312	7040,5073,4204,255520	TGFB1,PARN,MECP2,ELMOD2
WP2371	Parkinsons Disease Pathway	0.993944210505507	-0.006074200152705	83	6	0.00716845878136201	837	5312	2058,54205,839,1432,11315,27429	EPRS,CYCS,CASP6,MAPK14,PARK7,HTRA2
WP129	Matrix Metalloproteinases	0.994253939318155	-0.00576263280195491	30	1	0.001194743130227	837	5312	7077	TIMP2
WP2911	miRNA targets in ECM and membrane receptors	0.994453029815247	-0.0055624117529541	43	2	0.002389486260454	837	5312	3693,6383	ITGB5,SDC2
WP3893	Development and heterogeneity of the ILC family	0.995930871000849	-0.0040774304319442	32	1	0.001194743130227	837	5312	4783	NFIL3
WP58	Monoamine GPCRs	0.996575920432752	-0.00342995514381777	33	1	0.001194743130227	837	5312	154	ADRB2
WP2884	NRF2 pathway	0.997062775221024	-0.00294154688909144	143	12	0.014336917562724	837	5312	7040,55334,2730,2512,9817,7295,1728,6513,91252,3337,5052,10057	TGFB1,SLC39A9,GCLM,FTL,KEAP1,TXN,NQO1,SLC2A1,SLC39A13,DNAJB1,PRDX1,ABCC5
WP2849	Hematopoietic Stem Cell Differentiation	0.997420815105653	-0.00258251672187291	48	2	0.002389486260454	837	5312	7409,4773	VAV1,NFATC2
WP558	Complement and Coagulation Cascades	0.997574111147028	-0.00242883608874427	60	3	0.003584229390681	837	5312	1191,3998,2149	CLU,LMAN1,F2R
WP299	Nuclear Receptors in Lipid Metabolism and Toxicity	0.997575723648845	-0.0024272196669711	35	1	0.001194743130227	837	5312	19	ABCA1
WP43	Oxidation by Cytochrome P450	0.99842162778079	-0.001579619160906	63	3	0.003584229390681	837	5312	51706,1528,57404	CYB5R1,CYB5A,CYP20A1
WP2406	Cardiac Progenitor Differentiation	0.99881234893464	-0.00118835688178403	53	2	0.002389486260454	837	5312	7040,1432	TGFB1,MAPK14
WP2848	Differentiation Pathway	0.999743955043289	-0.000256077741817382	48	1	0.001194743130227	837	5312	7040	TGFB1
WP117	GPCRs, Other	0.999917831900731	-8.21714752518211e-05	95	4	0.004778972520908	837	5312	154,29933,1952,2149	ADRB2,GPR132,CELSR2,F2R
WP702	Metapathway biotransformation	0.99997479431113	-2.52060065389885e-05	177	11	0.013142174432497	837	5312	57106,373156,26151,80218,57404,231,51126,79807,2053,8514,2879	NAT14,GSTK1,NAT9,NAA50,CYP20A1,AKR1B1,NAA20,GSTCD,EPHX2,KCNAB2,GPX4
WP455	GPCRs, Class A Rhodopsin-like	0.999999999985085	-1.49151474021615e-11	259	2	0.002389486260454	837	5312	154,2149	ADRB2,F2R
WP2596	Gastric acid production	0.999999999999438	-5.62486978855962e-13	7	0	0	837	5312
WP699	Aflatoxin B1 metabolism	0.999999999999438	-5.62486978855962e-13	7	0	0	837	5312
WP3924	Hfe effect on hepcidin production	0.999999999999438	-5.62486978855962e-13	7	0	0	837	5312
WP1995	Effects of Nitric Oxide	0.999999999999438	-5.62486978855962e-13	7	0	0	837	5312
WP3601	Composition of Lipid Particles	1.00000000000105	1.05305432308975e-12	10	0	0	837	5312
WP2874	Liver X Receptor Pathway	1.00000000000105	1.05305432308975e-12	10	0	0	837	5312
WP496	Steroid Biosynthesis	1.00000000000105	1.05305432308975e-12	10	0	0	837	5312
WP2816	Felbamate Metabolism	1.00000000000158	1.58039206721305e-12	2	0	0	837	5312
WP2646	Lidocaine metabolism	1.00000000000158	1.58039206721305e-12	2	0	0	837	5312
WP2901	Gonadotropin-releasing hormone (GnRH) signaling	1.00000000000158	1.58039206721305e-12	2	0	0	837	5312
WP2866	mir34a and TGIF2 in osteoclastogenesis	1.00000000000158	1.58039206721305e-12	2	0	0	837	5312
WP2943	Hypoxia-mediated EMT and Stemness	1.00000000000158	1.58039206721305e-12	2	0	0	837	5312
WP3596	miR-517 relationship with ARCN1 and USP1	1.00000000000356	3.55758696427792e-12	5	0	0	837	5312
WP688	Catalytic cycle of mammalian Flavin-containing MonoOxygenases (FMOs)	1.00000000000356	3.55758696427792e-12	5	0	0	837	5312
WP2597	Secretion of Hydrochloric Acid in Parietal Cells	1.00000000000356	3.55758696427792e-12	5	0	0	837	5312
WP2542	Sulindac Metabolic Pathway	1.00000000000356	3.55758696427792e-12	5	0	0	837	5312
WP694	Arylamine metabolism	1.00000000000521	5.208719247273e-12	6	0	0	837	5312
WP1981	Thyroxine (Thyroid Hormone) Production	1.00000000000521	5.208719247273e-12	6	0	0	837	5312
WP1600	Nicotine Metabolism	1.00000000000521	5.208719247273e-12	6	0	0	837	5312
WP2190	One carbon donor	1.00000000000575	5.75031688931915e-12	1	0	0	837	5312
WP1	Statin Pathway	1.00000000000575	5.75031688931915e-12	1	0	0	837	5312
WP188	Focal Adhesion	1.00000000000575	5.75031688931915e-12	1	0	0	837	5312
WP3191	TSLP Signaling Pathway	1.00000000000575	5.75031688931915e-12	1	0	0	837	5312
WP3627	Gut-Liver Indole Metabolism	1.00000000000575	5.75031688931915e-12	1	0	0	837	5312
WP108	Selenium metabolism/Selenoproteins	1.00000000000575	5.75031688931915e-12	1	0	0	837	5312
WP661	Glucose Homeostasis	1.00000000000575	5.75031688931915e-12	1	0	0	837	5312
WP2536	Colchicine Metabolic Pathway	1.00000000000575	5.75031688931915e-12	1	0	0	837	5312
WP80	Nucleotide GPCRs	1.00000000000719	7.18977872158565e-12	11	0	0	837	5312
WP2854	Gene regulatory network modelling somitogenesis	1.00000000000719	7.18977872158565e-12	11	0	0	837	5312
WP1455	Serotonin Transporter Activity	1.00000000000719	7.18977872158565e-12	11	0	0	837	5312
WP3408	Evolocumab Mechanism	1.00000000000884	8.84189162858595e-12	3	0	0	837	5312
WP2846	Proprotein convertase subtilisin/kexin type 9 (PCSK9) mediated LDL receptor degradation	1.00000000000884	8.84189162858595e-12	3	0	0	837	5312
WP2491	Diclofenac Metabolic Pathway	1.00000000001032	1.03161950553224e-11	4	0	0	837	5312
WP2889	Oxytocin signaling	1.00000000001032	1.03161950553224e-11	4	0	0	837	5312
WP3633	Caffeine and Theobromine metabolism	1.00000000001032	1.03161950553224e-11	4	0	0	837	5312
WP897	Androgen receptor signaling pathway	1.00000000001032	1.03161950553224e-11	4	0	0	837	5312
WP521	Amino acid conjugation of benzoic acid	1.00000000001032	1.03161950553224e-11	4	0	0	837	5312
WP1603	Nicotine Activity on Chromaffin Cells	1.00000000001032	1.03161950553224e-11	4	0	0	837	5312
WP1133	Androgen receptor signaling pathway	1.00000000001032	1.03161950553224e-11	4	0	0	837	5312
WP2276	Glial Cell Differentiation	1.00000000001201	1.20130805749698e-11	8	0	0	837	5312
WP237	Glucocorticoid & Mineralcorticoid Metabolism	1.00000000001201	1.20130805749698e-11	8	0	0	837	5312
WP3407	FTO Obesity Variant Mechanism	1.00000000001201	1.20130805749698e-11	8	0	0	837	5312
WP1604	Codeine and Morphine Metabolism	1.00000000001201	1.20130805749698e-11	8	0	0	837	5312
WP3297	EV release from cardiac cells and their functional effects	1.00000000001317	1.31702362415482e-11	9	0	0	837	5312
WP3593	miR-148a/miR-31/FIH1/HIF1α-Notch signaling in glioblastoma	1.00000000001317	1.31702362415482e-11	9	0	0	837	5312
WP696	Benzo(a)pyrene metabolism	1.00000000001317	1.31702362415482e-11	9	0	0	837	5312
WP206	Fatty Acid Omega Oxidation	1.00000000001622	1.62211904643646e-11	15	0	0	837	5312
WP691	Tamoxifen metabolism	1.00000000001732	1.73201585219311e-11	21	0	0	837	5312
WP322	Osteoblast Signaling	1.00000000002108	2.10825497389629e-11	14	0	0	837	5312
WP272	Blood Clotting Cascade	1.00000000002412	2.41215077065472e-11	22	0	0	837	5312
WP545	Complement Activation	1.00000000002412	2.41215077065472e-11	22	0	0	837	5312
WP383	Striated Muscle Contraction	1.0000000000274	2.74015648233828e-11	38	0	0	837	5312
WP550	Biogenic Amine Synthesis	1.00000000002764	2.76393711694496e-11	16	0	0	837	5312
WP501	GPCRs, Class C Metabotropic glutamate, pheromone	1.00000000002764	2.76393711694496e-11	16	0	0	837	5312
WP3679	Cell-type Dependent Selectivity of CCK2R Signaling	1.00000000002788	2.78810181442825e-11	13	0	0	837	5312
WP334	GPCRs, Class B Secretin-like	1.00000000002884	2.88387942677712e-11	24	0	0	837	5312
WP2289	Drug Induction of Bile Acid Pathway	1.00000000002946	2.94593891081021e-11	17	0	0	837	5312
WP692	Sulfation Biotransformation Reaction	1.00000000003356	3.35635434189783e-11	18	0	0	837	5312
WP453	Inflammatory Response Pathway	1.00000000003622	3.62206126389146e-11	33	0	0	837	5312
WP24	Peptide GPCRs	1.0000000000408	4.07987424710287e-11	74	0	0	837	5312