Enter set sizes in the following table. N indicates the total number of objects (e.g., genes) in your analysis. You can then specify the size of up to four subsets (A, B, C, and D respectively) and all their 2-way, 3-way, and 4-way intersections. Use the Iterations menu to specify the number of simulations to perform; this will also determine the precision of the resulting P-values. When done, click the Submit button.