| P-value | ln(P) | Term | GO Tree | GO ID | # of Genes in Term | # of Target Genes in Term | # of Total Genes | # of Target Genes | Common Genes |
|---|
| 3.428e-08 | -17.19 | GOBERT_OLIGODENDROCYTE_DIFFERENTIATION_DN | MSigDB lists | GOBERT_OLIGODENDROCYTE_DIFFERENTIATION_DN | 994 | 41 | 17377 | 282 |
MXI1,DUSP8,RECK,CYP2J2,UBASH3B,LSM11,BACE1,ITPR2,SLC2A13,PRKCA,PFN2,FHOD3,NEO1,CPNE2,RALGPS2,EBF4,BNIP3,PDE4D,NCEH1,KIAA1549,TBC1D8,TMC7,PHLDB2,PDK1,PNRC1,SOX21,BNIP3L,TNS1,LHPP,PLEKHA1,SGK2,TBC1D16,JAM3,TCF7L1,GNAO1,PLEKHG1,P4HA1,CLMN,ARHGAP28,DBP,APBA2 |
| 6.417e-08 | -16.56 | carcinoid-endocrine_tumour | COSMIC cancer mutations | carcinoid-endocrine_tumour | 7964 | 173 | 17385 | 281 |
ARHGAP26,ACSL1,ACVR1,LGR4,RECK,HEBP1,PTPN21,CEBPA,ITPR2,ABAT,PRKCA,CACNB4,HMCN1,NCS1,CPNE2,FKBP9,PPM1E,MARVELD2,CFHR1,TMEM143,TLN2,TSHR,FANK1,TBC1D8,KLHL3,DSTN,CAPN5,SLC25A28,ABCC2,TNS1,PLEKHA1,ACVR2B,SGK2,SAV1,DYRK1B,TCF7L1,PLK2,RASGRF2,ERN1,ARHGAP28,MAPK13,TMOD2,TANC2,APBA2,TMEM63C,ZNF395,ZHX3,BVES,UBASH3B,CYP2J2,CYP4V2,SETBP1,CHADL,SLC36A4,SATB1,DYNC1I1,NIPSNAP3B,FHOD3,MTUS1,IL17D,NUMBL,RALGPS2,SLC30A4,MYC,EBF4,SRGAP1,GAN,BNIP3,MOXD1,STXBP1,GPR161,EPB41L5,BDNF,QSOX1,EFNA3,WDR25,WWC1,STRADB,PRDM1,LHPP,ARRDC4,B4GALNT3,ZNF558,ADAMTS3,KIAA0355,ISM1,LRRIQ3,EMILIN2,HK2,CLMN,RNF122,ZNF516,RASAL2,DOCK1,PLXNA2,RHPN2,COLEC10,KIF21B,RADIL,CBLN1,TIAM2,ZNF827,TMEM53,KMO,RPS6KL1,EEPD1,ZNF521,MAP7,MYH15,RAB27B,DNAH5,TMEM120B,FAM78B,ATP6AP1L,C3orf67,DZANK1,GAPDH,PDK1,UROS,SLC39A8,ADCY1,NLGN4X,SATB2,RAB38,TBC1D16,JAM3,CENPV,IQCK,LMLN,RBPMS2,WWTR1,PLEKHG1,P4HA1,DISP1,DBP,COBL,CCDC148,MXI1,NECAB2,TMEM132C,PRSS16,ARHGEF11,BACE1,CCNJL,NEO1,RGS17,GPR155,PRKCD,EHD3,GTF2F2,ACTA2,PRICKLE2,TRIM3,SGK1,KIAA0408,MN1,TMC7,MPP1,NUAK2,OGDHL,EXOG,PALLD,GPR137C,RERE,CTIF,TRIB3,FGR,FMO4,GNAO1,MAP2K6,KIAA0513,MYOM2,PHC1 |
| 9.523e-08 | -16.17 | ovary-other-neoplasm | COSMIC cancer mutations | ovary-other-neoplasm | 13098 | 247 | 17385 | 281 |
ARHGAP26,CCDC126,ACSL1,ACVR1,DUSP8,LGR4,RECK,HEBP1,LSM11,PTPN21,NDRG2,NRN1,ITPR2,ABAT,PRKCA,ABHD4,CACNB4,ABHD6,HMCN1,NCS1,EPDR1,EPCAM,CPNE2,FKBP9,PPM1E,PMAIP1,MARVELD2,CFHR1,TMEM143,TMEM37,TLN2,TSHR,FANK1,TBC1D8,PGBD5,ZNF391,KLHL23,KLHL3,WISP3,DSTN,CAPN5,BNIP3L,SLC25A28,TTC22,ABCC2,TNS1,PLEKHA1,ACVR2B,SGK2,SAV1,NT5DC2,PLEKHB1,SPNS1,SPATA9,TCF7L1,RASGRF2,ERN1,ALDOA,ARHGAP28,MAPK13,TMOD2,TANC2,APBA2,LONRF1,GPR63,SCN5A,RGS16,TMEM63C,RUNX2,ZNF395,ZHX3,BVES,UBASH3B,CYP2J2,FBXO4,CYP4V2,SETBP1,RASL11B,CHADL,SLC36A4,TNFRSF10C,SATB1,DYNC1I1,HPCAL4,NIPSNAP3B,FHOD3,MTUS1,IL17D,NUMBL,RALGPS2,SLC30A4,MYC,ZIC5,EBF4,SRGAP1,GAN,BNIP3,MOXD1,VGLL4,STXBP1,BARX1,GPR161,EPB41L5,BDNF,IL17RD,QSOX1,EFNA3,PPFIA4,WDR25,WWC1,STRADB,MAFB,SHISA2,PRDM1,LHPP,ARRDC4,B4GALNT3,ZNF558,KIAA0355,ADAMTS3,ISM1,LRRIQ3,QPCTL,EMILIN2,HK2,CLMN,IQSEC2,RNF122,ZNF516,RASAL2,DOCK1,ST14,C4A,FAM131C,CCDC110,PLXNA2,RHPN2,COLEC10,KIF21B,RADIL,TIAM2,TMEM53,ZNF827,KMO,RPS6KL1,DACT1,ZNF521,ZDHHC23,EEPD1,MAP7,MYH15,PJA1,RAB27B,DNAH5,TMEM120B,FAM78B,ATP6AP1L,HSPA2,C3orf67,DZANK1,PHLDB2,UROS,PDK1,SLC39A8,PTPN6,CYB5R2,SFXN4,ADCY1,NLGN4X,SATB2,WNT11,RAB38,TBC1D16,TRIQK,JAM3,CENPV,IQCK,LMLN,ANKRD31,WFS1,RBPMS2,WWTR1,PLEKHG1,P4HA1,TNFSF15,DISP1,DBP,KLHL31,COBL,CCDC148,MXI1,TMEM132C,NECAB2,PRSS16,ARHGEF11,BACE1,BIK,BLVRB,CCNJL,KIF5C,ARL2,OVOL2,ZNF219,NEO1,RGS17,GPR155,PRKCD,EHD3,RASD2,GTF2F2,ACTA2,CCDC122,TRIM3,PRICKLE2,SGK1,KIAA0408,SMPDL3A,PARP9,TMC7,MN1,B9D1,SLC40A1,MSX1,PXN,MPP1,OGDHL,PALLD,EXOG,TLR6,GPR137C,RERE,GPLD1,CTIF,TRIB3,FGR,MAP2K6,GNAO1,FMO4,KIAA0513,MYOM2,TNFRSF17,THAP10,RNF157,PKIA,DDIT3,B4GALT7,PHC1 |
| 2.207e-07 | -15.33 | prostate-carcinoma | COSMIC cancer mutations | prostate-carcinoma | 9227 | 191 | 17385 | 281 |
ARHGAP26,ACSL1,ACVR1,DUSP8,LGR4,LSM11,PTPN21,ALG1L,CEBPA,SLC2A13,ITPR2,PRKCA,ABHD4,CACNB4,ABHD6,HMCN1,NCS1,EPDR1,CPNE2,FKBP9,PPM1E,PMAIP1,TMEM37,TLN2,OR2W3,TSHR,FANK1,PGBD5,WISP3,EXOC6B,BNIP3L,SLC25A28,TTC22,ABCC2,TNS1,PLEKHA1,ACVR2B,SGK2,SAV1,NT5DC2,PLEKHB1,SPNS1,TCF7L1,PLK2,RASGRF2,ALDOA,MAPK13,TMOD2,TANC2,APBA2,SCN5A,RUNX2,ZNF395,ZHX3,BVES,UBASH3B,FBXO4,SETBP1,RASL11B,ATP6V1E2,SLC36A4,SATB1,DYNC1I1,NIPSNAP3B,FHOD3,MTUS1,NUMBL,RALGPS2,SLC30A4,MYC,ZIC5,EBF4,SRGAP1,BNIP3,NCEH1,MOXD1,VGLL4,GPR161,EPB41L5,BDNF,IL17RD,EFNA3,SPATA13,PPFIA4,WDR25,WWC1,STRADB,MAFB,SHISA2,LHPP,B4GALNT3,ZNF558,ADAMTS3,KIAA0355,LRRIQ3,EMILIN2,HK2,CLMN,IQSEC2,SMYD3,ZNF516,RASAL2,DOCK1,ST14,FAM131C,CCDC110,PLXNA2,RHPN2,COLEC10,KIF21B,RADIL,TIAM2,ZNF827,KMO,RPS6KL1,DACT1,ZNF521,EEPD1,MAP7,DAB2IP,MYH15,PDE4D,DNAH5,TMEM120B,FAM78B,HSPA2,C3orf67,PHLDB2,PDK1,SOX21,PTPN6,ADCY1,NLGN4X,SATB2,WNT11,RAB38,TBC1D16,JAM3,IQCK,LMLN,WFS1,RBPMS2,WWTR1,PLEKHG1,DISP1,KLHL31,COBL,KCTD1,CCDC148,NECAB2,TMEM132C,PRSS16,ARHGEF11,KIF5C,OVOL2,ZNF219,NEO1,RGS17,GPR155,PRKCD,RASD2,EHD3,GTF2F2,PRICKLE2,TRIM3,SGK1,CCDC122,PARP9,TMC7,MN1,SLC40A1,MSX1,PXN,MPP1,OGDHL,NUAK2,EXOG,PALLD,GPR137C,TLR6,RERE,CTIF,GPLD1,FGR,GNAO1,FMO4,MAP2K6,MYOM2,TNFRSF17,RNF157,DDIT3 |
| 4.921e-07 | -14.52 | haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-Burkitt_lymphoma | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-Burkitt_lymphoma | 2173 | 65 | 17385 | 281 |
ARHGAP26,LGR4,RASAL2,DOCK1,RECK,HEBP1,LSM11,PLXNA2,ITPR2,COLEC10,RADIL,HMCN1,EPDR1,ZNF521,MAP7,TLN2,DNAH5,FANK1,FAM78B,PGBD5,UROS,PDK1,SLC39A8,DSTN,ADCY1,NLGN4X,SATB2,TBC1D16,IQCK,TCF7L1,LMLN,RBPMS2,RASGRF2,WWTR1,TANC2,COBL,CCDC148,ARHGEF11,BVES,CYP2J2,UBASH3B,SETBP1,CCNJL,DYNC1I1,SATB1,FHOD3,MYC,SRGAP1,GTF2F2,EBF4,PRICKLE2,PARP9,SLC40A1,OGDHL,STRADB,PALLD,GPR137C,B4GALNT3,CTIF,RERE,KIAA0355,ADAMTS3,FMO4,GNAO1,LRRIQ3 |
| 4.921e-07 | -14.52 | Burkitt_lymphoma | COSMIC cancer mutations | Burkitt_lymphoma | 2173 | 65 | 17385 | 281 |
ARHGAP26,LGR4,RASAL2,DOCK1,RECK,HEBP1,LSM11,PLXNA2,ITPR2,COLEC10,RADIL,HMCN1,EPDR1,ZNF521,MAP7,TLN2,DNAH5,FANK1,FAM78B,PGBD5,UROS,PDK1,SLC39A8,DSTN,ADCY1,NLGN4X,SATB2,TBC1D16,IQCK,TCF7L1,LMLN,RBPMS2,RASGRF2,WWTR1,TANC2,COBL,CCDC148,ARHGEF11,BVES,CYP2J2,UBASH3B,SETBP1,CCNJL,DYNC1I1,SATB1,FHOD3,MYC,SRGAP1,GTF2F2,EBF4,PRICKLE2,PARP9,SLC40A1,OGDHL,STRADB,PALLD,GPR137C,B4GALNT3,CTIF,RERE,KIAA0355,ADAMTS3,FMO4,GNAO1,LRRIQ3 |
| 1.102e-06 | -13.72 | NUYTTEN_EZH2_TARGETS_UP | MSigDB lists | NUYTTEN_EZH2_TARGETS_UP | 968 | 37 | 17377 | 282 |
CCDC126,MXI1,RUNX2,ZNF395,BACE1,SETBP1,SLC2A13,GAS6,HERC6,NCS1,KMO,PMAIP1,MARVELD2,GPR155,SGK1,BNIP3,RAB27B,MOXD1,VGLL4,PARP9,PHLDB2,BDNF,QSOX1,PNRC1,PDK1,SHISA2,SLC25A28,ARRDC4,PLK2,HK2,KIAA0513,P4HA1,DLX2,SMYD3,KCTD1,DDIT3,PKIA |
| 1.315e-06 | -13.54 | MEISSNER_BRAIN_HCP_WITH_H3K4ME3_AND_H3K27ME3 | MSigDB lists | MEISSNER_BRAIN_HCP_WITH_H3K4ME3_AND_H3K27ME3 | 1016 | 38 | 17377 | 282 |
SCN5A,BVES,ST14,DOCK1,BIK,NDRG2,ABAT,OVOL2,SATB1,CBLN1,MTUS1,CPNE2,PMAIP1,ZIC5,EBF4,TMEM37,MOXD1,HSPA2,PHLDB2,BDNF,IL17RD,MSX1,SLC39A8,SOX21,NUAK2,MAFB,WNT11,SHISA2,SATB2,PRDM1,RBPMS2,RASGRF2,EMILIN2,WWTR1,HK2,ARHGAP28,DLX2,KCTD1 |
| 2.467e-06 | -12.91 | ovary | COSMIC cancer mutations | ovary | 15237 | 269 | 17385 | 281 |
ARHGAP26,ACVR1,DUSP8,LGR4,RECK,LSM11,ALG1L,CEBPA,PRKCA,ABHD6,NCS1,EPDR1,PMAIP1,CFHR1,TMEM37,TSHR,TBC1D8,KLHL23,KLHL3,WISP3,DSTN,BNIP3L,SLC25A28,ABCC2,TNS1,ACVR2B,SAV1,SPATA9,PLK2,RASGRF2,ALDOA,ARHGAP28,MAPK13,TMOD2,TANC2,SCN5A,TMEM63C,ZHX3,CYP2J2,SLC36A4,TNFRSF10C,DYNC1I1,HPCAL4,NIPSNAP3B,MTUS1,IL17D,RALGPS2,MYC,ZIC5,SRGAP1,MOXD1,STXBP1,GPR161,EPB41L5,BDNF,QSOX1,SHISA2,ARRDC4,OR11H4,ZNF558,ADAMTS3,ISM1,LRRIQ3,QPCTL,EMILIN2,CLMN,IQSEC2,ZNF516,RASAL2,ST14,C4A,FAM131C,CCDC110,PLXNA2,COLEC10,TIAM2,TMEM53,ZNF827,KMO,DACT1,DAB2IP,PJA1,PDE4D,RAB27B,DNAH5,ATP6AP1L,C3orf67,DZANK1,GAPDH,PDK1,CYB5R2,SFXN4,ADCY1,NLGN4X,SATB2,WNT11,RAB38,TBC1D16,TRIQK,IQCK,ZNF697,WFS1,WWTR1,PLEKHG1,P4HA1,TNFSF15,DBP,KLHL31,COBL,KCTD1,CCDC148,MXI1,TMEM132C,BACE1,BIK,CCNJL,KIF5C,ARL2,GAS6,ZNF219,NEO1,RGS17,GPR155,SMPDL3A,PARP9,TMC7,MN1,B9D1,SLC40A1,PXN,MPP1,GPR137C,GPLD1,TRIB3,FGR,GNAO1,MYOM2,TNFRSF17,DDIT3,B4GALT7,PHC1,CCDC126,ACSL1,HEBP1,PTPN21,NDRG2,NRN1,ABAT,ITPR2,SLC2A13,CACNB4,ABHD4,HMCN1,EPCAM,PPM1E,FKBP9,CPNE2,MARVELD2,DLX6,TMEM143,TLN2,FANK1,OR2W3,ZNF391,PGBD5,CAPN5,TTC22,PLEKHA1,SGK2,NT5DC2,PLEKHB1,DYRK1B,SPNS1,TCF7L1,ERN1,DLX2,APBA2,GPR63,LONRF1,RGS16,RUNX2,ZNF395,BVES,FBXO4,UBASH3B,CYP4V2,ATP6V1E2,RASL11B,SETBP1,CHADL,SATB1,PFN2,FHOD3,NUMBL,SLC30A4,GAN,EBF4,BNIP3,NCEH1,VGLL4,BARX1,IL17RD,SPATA13,EFNA3,MAFB,STRADB,WWC1,WDR25,PPFIA4,LHPP,PRDM1,B4GALNT3,KIAA0355,HK2,RNF122,DOCK1,RHPN2,KIF21B,RADIL,CBLN1,RPS6KL1,EEPD1,ZDHHC23,ZNF521,MAP7,MYH15,TMEM120B,HSPA2,FAM78B,PHLDB2,UROS,PTPN6,SLC39A8,JAM3,CENPV,IFT81,LMLN,ANKRD31,RBPMS2,DISP1,NECAB2,PRSS16,ARHGEF11,BLVRB,OVOL2,PRKCD,RASD2,EHD3,GTF2F2,ACTA2,PRICKLE2,TRIM3,SGK1,CCDC122,KIAA0408,MSX1,NUAK2,OGDHL,EXOG,PALLD,TLR6,CTIF,RERE,FMO4,MAP2K6,KIAA0513,THAP10,RNF157,PKIA |
| 2.593e-06 | -12.86 | TATTATA,MIR-374 | MSigDB lists | TATTATA,MIR-374 | 274 | 17 | 17377 | 282 |
SCN5A,MSX1,RUNX2,PNRC1,DUSP8,BACE1,PRDM1,RAB38,ABAT,NEO1,NUMBL,MAP2K6,PRKCD,ARHGAP28,PDE4D,IQSEC2,PKIA |
| 3.701e-06 | -12.51 | GSE11057_NAIVE_VS_EFF_MEMORY_CD4_TCELL_UP | MSigDB lists | GSE11057_NAIVE_VS_EFF_MEMORY_CD4_TCELL_UP | 168 | 13 | 17377 | 282 |
ZNF516,PDK1,IGIP,KLHL3,MPP1,DACT1,CCDC110,BNIP3L,PRICKLE2,PRKCA,SATB1,APBA2,CENPV |
| 3.781e-06 | -12.49 | GSE24634_TREG_VS_TCONV_POST_DAY10_IL4_CONVERSION_DN | MSigDB lists | GSE24634_TREG_VS_TCONV_POST_DAY10_IL4_CONVERSION_DN | 195 | 14 | 17377 | 282 |
QSOX1,FKBP9,FGR,ACSL1,LGR4,KMO,ST14,MAP2K6,BACE1,BLVRB,CEBPA,PALLD,APBA2,PLEKHB1 |
| 3.944e-06 | -12.44 | pancreas-carcinoid-endocrine_tumour | COSMIC cancer mutations | pancreas-carcinoid-endocrine_tumour | 7455 | 158 | 17385 | 281 |
ARHGAP26,ACSL1,ACVR1,LGR4,RECK,HEBP1,PTPN21,ITPR2,ABAT,PRKCA,CACNB4,HMCN1,NCS1,CPNE2,FKBP9,PPM1E,CFHR1,TMEM143,TLN2,TSHR,FANK1,KLHL3,DSTN,CAPN5,SLC25A28,ABCC2,TNS1,PLEKHA1,SGK2,SAV1,DYRK1B,TCF7L1,RASGRF2,ARHGAP28,TMOD2,TANC2,APBA2,TMEM63C,ZNF395,ZHX3,BVES,UBASH3B,CYP2J2,CYP4V2,SETBP1,CHADL,SLC36A4,SATB1,DYNC1I1,FHOD3,MTUS1,IL17D,NUMBL,RALGPS2,SLC30A4,EBF4,SRGAP1,GAN,BNIP3,MOXD1,STXBP1,GPR161,EPB41L5,BDNF,QSOX1,EFNA3,WDR25,WWC1,PRDM1,LHPP,ARRDC4,B4GALNT3,ZNF558,ADAMTS3,KIAA0355,ISM1,LRRIQ3,EMILIN2,HK2,CLMN,RNF122,ZNF516,RASAL2,DOCK1,PLXNA2,RHPN2,KIF21B,COLEC10,RADIL,CBLN1,TIAM2,ZNF827,TMEM53,KMO,EEPD1,ZNF521,MAP7,MYH15,RAB27B,DNAH5,TMEM120B,FAM78B,ATP6AP1L,C3orf67,DZANK1,GAPDH,PDK1,UROS,SLC39A8,ADCY1,NLGN4X,SATB2,RAB38,TBC1D16,JAM3,CENPV,IQCK,LMLN,RBPMS2,WWTR1,PLEKHG1,P4HA1,DISP1,DBP,COBL,CCDC148,NECAB2,MXI1,PRSS16,ARHGEF11,BACE1,CCNJL,NEO1,RGS17,GPR155,PRKCD,EHD3,GTF2F2,ACTA2,PRICKLE2,TRIM3,KIAA0408,MN1,TMC7,MPP1,OGDHL,EXOG,PALLD,GPR137C,RERE,CTIF,TRIB3,FMO4,GNAO1,MAP2K6,KIAA0513,MYOM2,PHC1 |
| 5.168e-06 | -12.17 | other | COSMIC cancer mutations | other | 15297 | 269 | 17385 | 281 |
ARHGAP26,ACVR1,DUSP8,LGR4,RECK,LSM11,ALG1L,CEBPA,PRKCA,ABHD6,NCS1,EPDR1,PMAIP1,CFHR1,TMEM37,TSHR,TBC1D8,KLHL23,KLHL3,WISP3,DSTN,BNIP3L,SLC25A28,ABCC2,TNS1,ACVR2B,SAV1,SPATA9,PLK2,RASGRF2,ALDOA,ARHGAP28,MAPK13,TMOD2,TANC2,SCN5A,TMEM63C,ZHX3,CYP2J2,SLC36A4,TNFRSF10C,DYNC1I1,HPCAL4,NIPSNAP3B,MTUS1,IL17D,RALGPS2,MYC,ZIC5,SRGAP1,MOXD1,STXBP1,GPR161,EPB41L5,BDNF,QSOX1,SHISA2,ARRDC4,ZNF558,ADAMTS3,ISM1,LRRIQ3,QPCTL,EMILIN2,CLMN,IQSEC2,SMYD3,ZNF516,RASAL2,ST14,C4A,FAM131C,CCDC110,PLXNA2,COLEC10,TIAM2,TMEM53,ZNF827,KMO,DACT1,DAB2IP,PJA1,PDE4D,RAB27B,DNAH5,ATP6AP1L,KIAA1549,C3orf67,DZANK1,GAPDH,PDK1,SOX21,CYB5R2,SFXN4,ADCY1,NLGN4X,SATB2,WNT11,RAB38,TBC1D16,TRIQK,IQCK,WFS1,WWTR1,PLEKHG1,P4HA1,TNFSF15,DBP,KLHL31,COBL,KCTD1,CCDC148,MXI1,TMEM132C,BACE1,BIK,CCNJL,KIF5C,ARL2,ZNF219,NEO1,RGS17,GPR155,SMPDL3A,PARP9,TMC7,MN1,B9D1,SLC40A1,PXN,MPP1,GPR137C,GPLD1,TRIB3,FGR,GNAO1,MYOM2,TNFRSF17,DDIT3,B4GALT7,PHC1,CCDC126,ACSL1,HEBP1,PTPN21,NDRG2,NRN1,ABAT,ITPR2,SLC2A13,CACNB4,ABHD4,HMCN1,EPCAM,PPM1E,FKBP9,CPNE2,MARVELD2,DLX6,TMEM143,TLN2,FANK1,OR2W3,ZNF391,PGBD5,PNRC1,CAPN5,TTC22,PLEKHA1,SGK2,NT5DC2,PLEKHB1,DYRK1B,SPNS1,TCF7L1,ERN1,APBA2,GPR63,LONRF1,RGS16,RUNX2,ZNF395,BVES,SCART1,FBXO4,UBASH3B,CYP4V2,RASL11B,SETBP1,CHADL,SATB1,FHOD3,NUMBL,SLC30A4,GAN,EBF4,BNIP3,NCEH1,VGLL4,BARX1,IL17RD,SPATA13,EFNA3,MAFB,STRADB,WWC1,WDR25,PPFIA4,LHPP,PRDM1,B4GALNT3,KIAA0355,HK2,RNF122,DOCK1,RHPN2,KIF21B,RADIL,CBLN1,KCTD15,RPS6KL1,EEPD1,ZDHHC23,ZNF521,MAP7,MYH15,TMEM120B,HSPA2,FAM78B,PHLDB2,UROS,PTPN6,SLC39A8,JAM3,CENPV,IFT81,LMLN,ANKRD31,RBPMS2,DISP1,NECAB2,PRSS16,ARHGEF11,BLVRB,OVOL2,PRKCD,RASD2,EHD3,GTF2F2,ACTA2,PRICKLE2,TRIM3,SGK1,CCDC122,KIAA0408,MSX1,NUAK2,OGDHL,EXOG,PALLD,TLR6,CTIF,RERE,FMO4,MAP2K6,KIAA0513,THAP10,RNF157,PKIA |
| 5.887e-06 | -12.04 | astrocytoma_Grade_III | COSMIC cancer mutations | astrocytoma_Grade_III | 1574 | 49 | 17385 | 281 |
ARHGAP26,SCN5A,CCDC148,ZNF516,ACVR1,RASAL2,DOCK1,BLVRB,PLXNA2,SETBP1,ARL2,PRKCA,ABHD4,DYNC1I1,HMCN1,FHOD3,FKBP9,ZNF827,RALGPS2,MARVELD2,RPS6KL1,TMEM143,GTF2F2,MAP7,TRIM3,MYH15,TLN2,MOXD1,DNAH5,OR2W3,KIAA1549,PGBD5,MN1,QSOX1,PHLDB2,EXOC6B,WDR25,SGK2,CTIF,GPLD1,ADAMTS3,PLK2,MAP2K6,EMILIN2,TNFSF15,KLHL31,TANC2,COBL,B4GALT7 |
| 6.311e-06 | -11.97 | GOZGIT_ESR1_TARGETS_DN | MSigDB lists | GOZGIT_ESR1_TARGETS_DN | 680 | 28 | 17377 | 282 |
EPB41L5,RUNX2,DUSP8,KLHL23,SLC39A8,SPATA13,ADCY1,ABAT,FAM198B,PRKCA,HERC6,ABHD4,CACNB4,GPR137C,PFN2,HMCN1,PLEKHB1,PPM1E,KCTD15,PLK2,SRGAP1,KIAA0513,PRICKLE2,SGK1,TANC2,RAB27B,PKIA,C3orf67 |
| 1.090e-05 | -11.43 | PH-like_dom_sf | interpro domains | IPR011993 | 410 | 20 | 18492 | 296 |
EPB41L5,ARHGAP26,PHLDB2,ARHGEF11,PTPN21,SPATA13,TNS1,PLEKHA1,GRK3,TIAM2,PLEKHB1,NUMBL,RALGPS2,RASGRF2,PLEKHG1,DAB2IP,TLN2,IQSEC2,APBA2,TBC1D8 |
| 1.166e-05 | -11.36 | UEDA_CENTRAL_CLOCK | MSigDB lists | UEDA_CENTRAL_CLOCK | 87 | 9 | 17377 | 282 |
RGS16,PNRC1,PLK2,RASL11B,SGK1,P4HA1,DBP,PLEKHA1,SMPDL3A |
| 1.166e-05 | -11.36 | ELVIDGE_HIF1A_TARGETS_DN | MSigDB lists | ELVIDGE_HIF1A_TARGETS_DN | 87 | 9 | 17377 | 282 |
QSOX1,MXI1,PDK1,ZNF395,HK2,BNIP3L,EFNA3,P4HA1,BNIP3 |
| 1.195e-05 | -11.33 | haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm | 7517 | 157 | 17385 | 281 |
ARHGAP26,CCDC126,ACVR1,LGR4,RECK,LSM11,PTPN21,NRN1,CEBPA,ITPR2,PRKCA,ABHD6,HMCN1,NCS1,EPDR1,EPCAM,FKBP9,PPM1E,MARVELD2,CFHR1,TMEM143,TMEM37,TLN2,TSHR,FANK1,PGBD5,KLHL3,DSTN,CAPN5,BNIP3L,ABCC2,TNS1,PLEKHA1,ACVR2B,SGK2,NT5DC2,SPATA9,TCF7L1,RASGRF2,ERN1,ARHGAP28,TANC2,APBA2,LONRF1,TMEM63C,SCART1,ZHX3,UBASH3B,CYP2J2,CYP4V2,SETBP1,SLC36A4,SATB1,DYNC1I1,FHOD3,MTUS1,RALGPS2,MYC,EBF4,SRGAP1,GAN,MOXD1,VGLL4,STXBP1,EPB41L5,BDNF,QSOX1,EFNA3,PPFIA4,WDR25,WWC1,SHISA2,PRDM1,LHPP,ARRDC4,B4GALNT3,ZNF558,ADAMTS3,KIAA0355,ISM1,LRRIQ3,QPCTL,EMILIN2,HK2,CLMN,RNF122,SMYD3,ZNF516,RASAL2,DOCK1,PLXNA2,RHPN2,KIF21B,COLEC10,RADIL,TIAM2,ZNF827,KMO,ZDHHC23,EEPD1,ZNF521,MAP7,MYH15,DNAH5,TMEM120B,FAM78B,C3orf67,DZANK1,GAPDH,PDK1,UROS,SLC39A8,SFXN4,ADCY1,NLGN4X,SATB2,RAB38,TBC1D16,JAM3,IQCK,WFS1,WWTR1,PLEKHG1,TNFSF15,DISP1,COBL,CCDC148,NECAB2,MXI1,ARHGEF11,BLVRB,CCNJL,NEO1,RGS17,GPR155,PRKCD,RASD2,EHD3,GTF2F2,PRICKLE2,TRIM3,SGK1,CCDC122,B9D1,MN1,TMC7,OGDHL,PALLD,GPR137C,RERE,CTIF,FGR,GNAO1,FMO4,MAP2K6,MYOM2,THAP10 |
| 1.277e-05 | -11.27 | QI_HYPOXIA | MSigDB lists | QI_HYPOXIA | 135 | 11 | 17377 | 282 |
DYRK1B,MXI1,PDK1,ALDOA,CAPN5,HK2,NDRG2,P4HA1,NRN1,BNIP3,KIF21B |
| 1.371e-05 | -11.20 | digestive system development | biological process | GO:0055123 | 141 | 11 | 17256 | 270 |
EPB41L5,LGR4,DACT1,RBPMS2,WNT11,PRDM1,OVOL2,ACVR2B,SAV1,BARX1,COBL |
| 1.387e-05 | -11.19 | MASSARWEH_TAMOXIFEN_RESISTANCE_UP | MSigDB lists | MASSARWEH_TAMOXIFEN_RESISTANCE_UP | 519 | 23 | 17377 | 282 |
ACVR1,ACSL1,CYP2J2,SPATA13,WWC1,RASL11B,NLGN4X,FAM198B,CENPV,MTUS1,ZNF827,TRIB3,ZNF697,EHD3,GAN,KIAA0513,PRICKLE2,PDE4D,NCEH1,TLN2,RAB27B,PKIA,TBC1D8 |
| 1.697e-05 | -10.98 | prostate | COSMIC cancer mutations | prostate | 14295 | 256 | 17385 | 281 |
ARHGAP26,CCDC126,ACSL1,ACVR1,DUSP8,LGR4,RECK,HEBP1,LSM11,PTPN21,ALG1L,NDRG2,CEBPA,SLC2A13,ITPR2,ABAT,PRKCA,ABHD4,CACNB4,ABHD6,HMCN1,NCS1,EPDR1,EPCAM,CPNE2,FKBP9,PPM1E,PMAIP1,DLX6,CFHR1,TMEM143,TMEM37,TLN2,OR2W3,TSHR,FANK1,TBC1D8,PGBD5,KLHL23,KLHL3,WISP3,EXOC6B,DSTN,CAPN5,BNIP3L,SLC25A28,TTC22,ABCC2,TNS1,PLEKHA1,ACVR2B,SGK2,SAV1,NT5DC2,PLEKHB1,SPNS1,SPATA9,TCF7L1,PLK2,RASGRF2,ALDOA,ARHGAP28,MAPK13,TMOD2,TANC2,APBA2,LONRF1,GPR63,SCN5A,RGS16,TMEM63C,RUNX2,ZNF395,ZHX3,BVES,UBASH3B,CYP2J2,FBXO4,CYP4V2,SETBP1,RASL11B,ATP6V1E2,CHADL,SLC36A4,TNFRSF10C,PFN2,SATB1,DYNC1I1,HPCAL4,NIPSNAP3B,FHOD3,MTUS1,IL17D,NUMBL,RALGPS2,SLC30A4,MYC,ZIC5,EBF4,SRGAP1,GAN,BNIP3,NCEH1,MOXD1,VGLL4,STXBP1,GPR161,EPB41L5,BDNF,IL17RD,QSOX1,EFNA3,SPATA13,PPFIA4,WDR25,WWC1,STRADB,MAFB,SHISA2,PRDM1,LHPP,ARRDC4,OR11H4,B4GALNT3,ZNF558,KIAA0355,ADAMTS3,ISM1,LRRIQ3,EMILIN2,HK2,CLMN,IQSEC2,RNF122,SMYD3,ZNF516,RASAL2,DOCK1,ST14,FAM131C,CCDC110,PLXNA2,RHPN2,FAM198B,COLEC10,KIF21B,RADIL,CBLN1,TIAM2,TMEM53,ZNF827,KMO,RPS6KL1,DACT1,ZNF521,EEPD1,ZDHHC23,MAP7,DAB2IP,MYH15,PJA1,PDE4D,RAB27B,DNAH5,TMEM120B,FAM78B,ATP6AP1L,HSPA2,C3orf67,DZANK1,PHLDB2,GAPDH,PDK1,SLC39A8,SOX21,PTPN6,CYB5R2,SFXN4,ADCY1,NLGN4X,SATB2,WNT11,RAB38,TBC1D16,TRIQK,JAM3,IQCK,IFT81,LMLN,ANKRD31,WFS1,RBPMS2,WWTR1,PLEKHG1,P4HA1,TNFSF15,DISP1,KLHL31,COBL,KCTD1,CCDC148,MXI1,TMEM132C,NECAB2,PRSS16,ARHGEF11,BACE1,BIK,BLVRB,CCNJL,KIF5C,ARL2,OVOL2,ZNF219,NEO1,RGS17,GPR155,PRKCD,EHD3,RASD2,GTF2F2,ACTA2,CCDC122,TRIM3,PRICKLE2,SGK1,KIAA0408,SMPDL3A,PARP9,TMC7,MN1,B9D1,SLC40A1,MSX1,PXN,MPP1,OGDHL,NUAK2,PALLD,EXOG,TLR6,GPR137C,RERE,GPLD1,CTIF,FGR,MAP2K6,GNAO1,FMO4,KIAA0513,MYOM2,TNFRSF17,RNF157,DDIT3,B4GALT7,PHC1 |
| 1.863e-05 | -10.89 | GSE29618_MONOCYTE_VS_PDC_DAY7_FLU_VACCINE_UP | MSigDB lists | GSE29618_MONOCYTE_VS_PDC_DAY7_FLU_VACCINE_UP | 195 | 13 | 17377 | 282 |
ARHGAP26,FGR,GAPDH,ACSL1,PXN,BLVRB,ALDOA,HK2,KIAA0513,MAFB,SGK1,CEBPA,FAM198B |
| 1.940e-05 | -10.85 | CRX_NRL_DN.V1_DN | MSigDB lists | CRX_NRL_DN.V1_DN | 116 | 10 | 17377 | 282 |
IL17D,QSOX1,HEBP1,RASGRF2,WWC1,KIF5C,PRDM1,RAB27B,JAM3,SMPDL3A |
| 1.975e-05 | -10.83 | KRIEG_HYPOXIA_NOT_VIA_KDM3A | MSigDB lists | KRIEG_HYPOXIA_NOT_VIA_KDM3A | 684 | 27 | 17377 | 282 |
QSOX1,MXI1,GAPDH,PDK1,PNRC1,SLC39A8,MPP1,CAPN5,BNIP3L,EFNA3,SAV1,NT5DC2,MTUS1,TRIB3,KCTD15,ADAMTS3,MYC,ALDOA,HK2,KIAA0513,P4HA1,BNIP3,DAB2IP,TANC2,TMEM120B,GPR161,TBC1D8 |
| 2.027e-05 | -10.81 | LEE_BMP2_TARGETS_UP | MSigDB lists | LEE_BMP2_TARGETS_UP | 685 | 27 | 17377 | 282 |
IL17RD,SLC40A1,MSX1,TMEM132C,PNRC1,ZNF395,ST14,RECK,SLC39A8,BLVRB,CAPN5,CYP4V2,NDRG2,ITPR2,ABHD4,SATB1,RADIL,RERE,EPCAM,PPM1E,WFS1,RASD2,ERN1,ZNF521,DBP,KCTD1,SMPDL3A |
| 2.473e-05 | -10.61 | regulation of signaling | biological process | GO:0023051 | 3600 | 85 | 17256 | 270 |
ARHGAP26,ACVR1,DUSP8,LGR4,RASAL2,NDRG2,ITPR2,ABAT,PRKCA,ABHD6,CBLN1,TIAM2,PMAIP1,KMO,DACT1,DAB2IP,PDE4D,EPHB6,WISP3,PTPN6,NLGN4X,WNT11,ACVR2B,PLEKHA1,TBC1D16,TCF7L1,RASGRF2,PLK2,WFS1,RBPMS2,ERN1,WWTR1,PLEKHG1,ARHGAP28,TNFSF15,TMOD2,DISP1,DLX2,APBA2,RGS16,NECAB2,RUNX2,BVES,ARHGEF11,UBASH3B,BACE1,BIK,ARL2,RASL11B,GAS6,TNFRSF10C,PFN2,MYORG,NEO1,IL17D,RGS17,RALGPS2,MYC,PRKCD,EHD3,RASD2,SRGAP1,INAVA,BNIP3,STXBP1,BARX1,GPR161,PARP9,BDNF,PXN,MSX1,SPATA13,WWC1,STRADB,SHISA2,GAREM1,PRDM1,TLR6,GPLD1,TRIB3,FGR,ADAMTS3,MAP2K6,IQSEC2,DDIT3 |
| 2.621e-05 | -10.55 | acute_lymphoblastic_B_cell_leukaemia | COSMIC cancer mutations | acute_lymphoblastic_B_cell_leukaemia | 3911 | 93 | 17385 | 281 |
ARHGAP26,ACVR1,DUSP8,LGR4,DOCK1,ST14,PLXNA2,CEBPA,ITPR2,KIF21B,CACNB4,RADIL,CBLN1,HMCN1,TIAM2,EPDR1,ZNF827,KMO,MARVELD2,ZNF521,TMEM143,MAP7,DAB2IP,TMEM37,TLN2,DNAH5,TMEM120B,TSHR,FANK1,TBC1D8,ZNF391,DZANK1,PHLDB2,PDK1,WISP3,PTPN6,CYB5R2,CAPN5,ADCY1,NLGN4X,SATB2,WNT11,TNS1,ABCC2,CENPV,PLEKHB1,IQCK,RASGRF2,WWTR1,ARHGAP28,APBA2,COBL,LONRF1,TMEM63C,SCN5A,CCDC148,NECAB2,TMEM132C,ZHX3,UBASH3B,CCNJL,SETBP1,CHADL,OVOL2,DYNC1I1,FHOD3,NUMBL,RALGPS2,SLC30A4,PRKCD,EBF4,SRGAP1,GTF2F2,PRICKLE2,TMC7,QSOX1,SLC40A1,OGDHL,WWC1,SHISA2,LHPP,PRDM1,EXOG,PALLD,B4GALNT3,RERE,ADAMTS3,MAP2K6,LRRIQ3,HK2,KIAA0513,MYOM2,PHC1 |
| 2.621e-05 | -10.55 | haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-acute_lymphoblastic_B_cell_leukaemia | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-acute_lymphoblastic_B_cell_leukaemia | 3911 | 93 | 17385 | 281 |
ARHGAP26,ACVR1,DUSP8,LGR4,DOCK1,ST14,PLXNA2,CEBPA,ITPR2,KIF21B,CACNB4,RADIL,CBLN1,HMCN1,TIAM2,EPDR1,ZNF827,KMO,MARVELD2,ZNF521,TMEM143,MAP7,DAB2IP,TMEM37,TLN2,DNAH5,TMEM120B,TSHR,FANK1,TBC1D8,ZNF391,DZANK1,PHLDB2,PDK1,WISP3,PTPN6,CYB5R2,CAPN5,ADCY1,NLGN4X,SATB2,WNT11,TNS1,ABCC2,CENPV,PLEKHB1,IQCK,RASGRF2,WWTR1,ARHGAP28,APBA2,COBL,LONRF1,TMEM63C,SCN5A,CCDC148,NECAB2,TMEM132C,ZHX3,UBASH3B,CCNJL,SETBP1,CHADL,OVOL2,DYNC1I1,FHOD3,NUMBL,RALGPS2,SLC30A4,PRKCD,EBF4,SRGAP1,GTF2F2,PRICKLE2,TMC7,QSOX1,SLC40A1,OGDHL,WWC1,SHISA2,LHPP,PRDM1,EXOG,PALLD,B4GALNT3,RERE,ADAMTS3,MAP2K6,LRRIQ3,HK2,KIAA0513,MYOM2,PHC1 |
| 2.794e-05 | -10.49 | GSE37416_CTRL_VS_6H_F_TULARENSIS_LVS_NEUTROPHIL_DN | MSigDB lists | GSE37416_CTRL_VS_6H_F_TULARENSIS_LVS_NEUTROPHIL_DN | 174 | 12 | 17377 | 282 |
B9D1,TCF7L1,PDK1,ZNF395,ALDOA,HK2,BNIP3L,EFNA3,P4HA1,BNIP3,VGLL4,HPCAL4 |
| 2.841e-05 | -10.47 | kidney-other-neoplasm | COSMIC cancer mutations | kidney-other-neoplasm | 10949 | 209 | 17385 | 281 |
ARHGAP26,CCDC126,ACSL1,ACVR1,DUSP8,LGR4,RECK,HEBP1,PTPN21,NRN1,ITPR2,ABAT,PRKCA,ABHD4,CACNB4,ABHD6,HMCN1,NCS1,EPDR1,EPCAM,CPNE2,FKBP9,PPM1E,DLX6,MARVELD2,CFHR1,TMEM143,TMEM37,TLN2,TSHR,FANK1,PGBD5,PNRC1,KLHL3,DSTN,CAPN5,BNIP3L,SLC25A28,ABCC2,TNS1,PLEKHA1,ACVR2B,SGK2,SAV1,NT5DC2,PLEKHB1,SPNS1,SPATA9,TCF7L1,RASGRF2,ARHGAP28,MAPK13,TMOD2,TANC2,APBA2,LONRF1,SCN5A,TMEM63C,RGS16,RUNX2,ZHX3,BVES,UBASH3B,CYP2J2,FBXO4,CYP4V2,SETBP1,RASL11B,CHADL,TNFRSF10C,SATB1,DYNC1I1,NIPSNAP3B,FHOD3,MTUS1,NUMBL,RALGPS2,SLC30A4,EBF4,SRGAP1,GAN,BNIP3,NCEH1,MOXD1,VGLL4,STXBP1,GPR161,EPB41L5,BDNF,QSOX1,PPFIA4,WDR25,WWC1,STRADB,PRDM1,LHPP,ARRDC4,B4GALNT3,ZNF558,ADAMTS3,KIAA0355,ISM1,LRRIQ3,EMILIN2,HK2,CLMN,RNF122,ZNF516,RASAL2,DOCK1,ST14,C4A,FAM131C,CCDC110,PLXNA2,RHPN2,COLEC10,KIF21B,RADIL,CBLN1,TIAM2,TMEM53,ZNF827,KCTD15,KMO,RPS6KL1,DACT1,ZNF521,ZDHHC23,EEPD1,MAP7,MYH15,PDE4D,RAB27B,DNAH5,TMEM120B,FAM78B,ATP6AP1L,C3orf67,DZANK1,PHLDB2,GAPDH,UROS,PDK1,SLC39A8,CYB5R2,SFXN4,ADCY1,NLGN4X,SATB2,WNT11,RAB38,TBC1D16,JAM3,CENPV,IQCK,LMLN,ANKRD31,RBPMS2,WWTR1,PLEKHG1,P4HA1,TNFSF15,DISP1,COBL,KCTD1,CCDC148,MXI1,NECAB2,PRSS16,ARHGEF11,BACE1,BLVRB,CCNJL,ARL2,OVOL2,NEO1,RGS17,GPR155,EHD3,GTF2F2,PRICKLE2,TRIM3,SGK1,CCDC122,KIAA0408,PARP9,TMC7,MN1,B9D1,MSX1,MPP1,OGDHL,NUAK2,EXOG,PALLD,GPR137C,RERE,GPLD1,CTIF,TRIB3,FGR,GNAO1,MAP2K6,KIAA0513,MYOM2,RNF157,B4GALT7,PHC1 |
| 3.063e-05 | -10.39 | HOELZEL_NF1_TARGETS_DN | MSigDB lists | HOELZEL_NF1_TARGETS_DN | 98 | 9 | 17377 | 282 |
BDNF,NECAB2,ZNF395,DLX6,SLC39A8,ADCY1,ARHGAP28,SATB1,HMCN1 |
| 3.340e-05 | -10.31 | digestive tract development | biological process | GO:0048565 | 128 | 10 | 17256 | 270 |
EPB41L5,LGR4,DACT1,RBPMS2,WNT11,PRDM1,OVOL2,ACVR2B,SAV1,COBL |
| 3.534e-05 | -10.25 | - | gene3d domains | 2.30.29.30 | 410 | 20 | 8148 | 145 |
EPB41L5,ARHGAP26,PHLDB2,ARHGEF11,PTPN21,SPATA13,TNS1,PLEKHA1,GRK3,TIAM2,PLEKHB1,NUMBL,RALGPS2,RASGRF2,PLEKHG1,DAB2IP,TLN2,IQSEC2,APBA2,TBC1D8 |
| 3.599e-05 | -10.23 | ELVIDGE_HIF1A_AND_HIF2A_TARGETS_DN | MSigDB lists | ELVIDGE_HIF1A_AND_HIF2A_TARGETS_DN | 100 | 9 | 17377 | 282 |
QSOX1,MXI1,PDK1,ZNF395,HK2,BNIP3L,EFNA3,P4HA1,BNIP3 |
| 3.712e-05 | -10.20 | NRL_DN.V1_DN | MSigDB lists | NRL_DN.V1_DN | 125 | 10 | 17377 | 282 |
IL17D,QSOX1,FKBP9,RASGRF2,WWC1,KIF5C,PRDM1,MOXD1,JAM3,SMPDL3A |
| 4.193e-05 | -10.08 | HARRIS_HYPOXIA | MSigDB lists | HARRIS_HYPOXIA | 79 | 8 | 17377 | 282 |
GAPDH,ALDOA,BIK,HK2,BNIP3L,P4HA1,BNIP3,DDIT3 |
| 4.586e-05 | -9.99 | GSE32986_GMCSF_VS_GMCSF_AND_CURDLAN_HIGHDOSE_STIM_DC_UP | MSigDB lists | GSE32986_GMCSF_VS_GMCSF_AND_CURDLAN_HIGHDOSE_STIM_DC_UP | 183 | 12 | 17377 | 282 |
SLC40A1,MXI1,GPR155,HEBP1,PTPN21,HK2,KIAA0513,MAFB,SLC36A4,CEBPA,DBP,GAS6 |
| 4.586e-05 | -9.99 | GSE9650_EFFECTOR_VS_EXHAUSTED_CD8_TCELL_DN | MSigDB lists | GSE9650_EFFECTOR_VS_EXHAUSTED_CD8_TCELL_DN | 183 | 12 | 17377 | 282 |
EPCAM,PHLDB2,RGS16,MSX1,ACSL1,PNRC1,SCAMP1,GNAO1,WFS1,CYP4V2,PLEKHA1,GPLD1 |
| 4.911e-05 | -9.92 | lymphoid_neoplasm | COSMIC cancer mutations | lymphoid_neoplasm | 12607 | 232 | 17385 | 281 |
ARHGAP26,CCDC126,ACVR1,DUSP8,LGR4,RECK,HEBP1,LSM11,PTPN21,NRN1,CEBPA,ITPR2,ABAT,PRKCA,CACNB4,ABHD6,HMCN1,NCS1,EPDR1,EPCAM,FKBP9,PPM1E,MARVELD2,CFHR1,TMEM143,TMEM37,TLN2,OR2W3,TSHR,FANK1,ZNF391,TBC1D8,PGBD5,KLHL23,KLHL3,WISP3,EXOC6B,DSTN,CAPN5,BNIP3L,TTC22,SLC25A28,ABCC2,TNS1,ACVR2B,PLEKHA1,SGK2,SAV1,NT5DC2,PLEKHB1,SPATA9,SPNS1,DYRK1B,TCF7L1,PLK2,RASGRF2,ERN1,ARHGAP28,MAPK13,DLX2,TANC2,APBA2,LONRF1,SCN5A,TMEM63C,ZNF395,SCART1,ZHX3,BVES,CYP2J2,FBXO4,UBASH3B,CYP4V2,ATP6V1E2,SETBP1,CHADL,SLC36A4,SATB1,DYNC1I1,FHOD3,MTUS1,NUMBL,SLC30A4,RALGPS2,MYC,ZIC5,SRGAP1,EBF4,GAN,BNIP3,MOXD1,NCEH1,VGLL4,STXBP1,GPR161,EPB41L5,BDNF,QSOX1,IL17RD,EFNA3,SPATA13,PPFIA4,WDR25,WWC1,STRADB,SHISA2,PRDM1,LHPP,OR11H4,ARRDC4,B4GALNT3,ZNF558,KIAA0355,ADAMTS3,ISM1,QPCTL,LRRIQ3,EMILIN2,HK2,CLMN,RNF122,SMYD3,ZNF516,RASAL2,ST14,DOCK1,CCDC110,PLXNA2,RHPN2,FAM198B,KIF21B,COLEC10,RADIL,CBLN1,TIAM2,TMEM53,ZNF827,KMO,RPS6KL1,ZDHHC23,EEPD1,ZNF521,MAP7,DAB2IP,MYH15,PDE4D,DNAH5,TMEM120B,FAM78B,ATP6AP1L,HSPA2,C3orf67,DZANK1,PHLDB2,GAPDH,UROS,PDK1,SLC39A8,PTPN6,CYB5R2,SFXN4,ADCY1,NLGN4X,WNT11,SATB2,RAB38,TBC1D16,JAM3,CENPV,IQCK,LMLN,RBPMS2,WFS1,WWTR1,PLEKHG1,P4HA1,TNFSF15,DISP1,KLHL31,COBL,CCDC148,TMEM132C,NECAB2,MXI1,PRSS16,ARHGEF11,BACE1,BLVRB,BIK,CCNJL,KIF5C,OVOL2,ZNF219,NEO1,RGS17,GPR155,PRKCD,EHD3,RASD2,GTF2F2,ACTA2,SGK1,PRICKLE2,TRIM3,CCDC122,PARP9,B9D1,TMC7,MN1,SLC40A1,MPP1,NUAK2,OGDHL,EXOG,PALLD,GPR137C,TLR6,RERE,GPLD1,CTIF,TRIB3,FGR,FMO4,MAP2K6,GNAO1,KIAA0513,ZNF474,MYOM2,THAP10,RNF157,DDIT3,PHC1 |
| 4.918e-05 | -9.92 | GSE26495_NAIVE_VS_PD1HIGH_CD8_TCELL_UP | MSigDB lists | GSE26495_NAIVE_VS_PD1HIGH_CD8_TCELL_UP | 156 | 11 | 17377 | 282 |
PDK1,SFXN4,CYP2J2,CAPN5,STRADB,RHPN2,PRKCA,RNF157,STXBP1,HPCAL4,PKIA |
| 5.098e-05 | -9.88 | GSE5589_WT_VS_IL6_KO_LPS_STIM_MACROPHAGE_45MIN_DN | MSigDB lists | GSE5589_WT_VS_IL6_KO_LPS_STIM_MACROPHAGE_45MIN_DN | 185 | 12 | 17377 | 282 |
MN1,C2orf88,CPNE2,ZNF516,CYB5R2,WFS1,DAB2IP,SAV1,ZNF219,SATB1,STXBP1,NCS1 |
| 5.658e-05 | -9.78 | GSE9650_NAIVE_VS_EFF_CD8_TCELL_UP | MSigDB lists | GSE9650_NAIVE_VS_EFF_CD8_TCELL_UP | 187 | 12 | 17377 | 282 |
PDK1,RALGPS2,SCAMP1,MPP1,MYC,WFS1,MAP7,P4HA1,PLEKHA1,TLR6,SATB1,RERE |
| 5.658e-05 | -9.78 | KAECH_NAIVE_VS_DAY8_EFF_CD8_TCELL_UP | MSigDB lists | KAECH_NAIVE_VS_DAY8_EFF_CD8_TCELL_UP | 187 | 12 | 17377 | 282 |
IFT81,PDK1,RALGPS2,CYP2J2,MYC,WFS1,MAP7,P4HA1,PLEKHA1,SATB1,TLR6,RERE |
| 5.680e-05 | -9.78 | neoplasm | COSMIC cancer mutations | neoplasm | 15237 | 266 | 17385 | 281 |
ARHGAP26,ACVR1,DUSP8,LGR4,RECK,LSM11,ALG1L,CEBPA,PRKCA,ABHD6,NCS1,EPDR1,PMAIP1,CFHR1,TMEM37,TSHR,TBC1D8,KLHL23,KLHL3,WISP3,DSTN,BNIP3L,SLC25A28,ABCC2,TNS1,ACVR2B,SAV1,SPATA9,PLK2,RASGRF2,ALDOA,ARHGAP28,MAPK13,TMOD2,TANC2,SCN5A,TMEM63C,ZHX3,CYP2J2,SLC36A4,TNFRSF10C,DYNC1I1,HPCAL4,NIPSNAP3B,MTUS1,IL17D,RALGPS2,MYC,ZIC5,SRGAP1,MOXD1,STXBP1,GPR161,EPB41L5,BDNF,QSOX1,SHISA2,ARRDC4,ZNF558,ADAMTS3,ISM1,LRRIQ3,QPCTL,EMILIN2,CLMN,IQSEC2,SMYD3,ZNF516,RASAL2,ST14,C4A,FAM131C,CCDC110,PLXNA2,COLEC10,TIAM2,TMEM53,ZNF827,KMO,DACT1,PJA1,PDE4D,RAB27B,DNAH5,ATP6AP1L,C3orf67,DZANK1,GAPDH,PDK1,SOX21,CYB5R2,SFXN4,ADCY1,NLGN4X,SATB2,WNT11,RAB38,TBC1D16,TRIQK,IQCK,WFS1,WWTR1,PLEKHG1,P4HA1,TNFSF15,DBP,KLHL31,COBL,KCTD1,CCDC148,MXI1,TMEM132C,BACE1,BIK,CCNJL,KIF5C,ARL2,ZNF219,NEO1,RGS17,GPR155,SMPDL3A,PARP9,TMC7,MN1,B9D1,SLC40A1,PXN,MPP1,GPR137C,GPLD1,TRIB3,FGR,GNAO1,MYOM2,TNFRSF17,DDIT3,B4GALT7,PHC1,CCDC126,ACSL1,HEBP1,PTPN21,NDRG2,NRN1,ABAT,ITPR2,SLC2A13,CACNB4,ABHD4,HMCN1,EPCAM,PPM1E,FKBP9,CPNE2,MARVELD2,DLX6,TMEM143,TLN2,FANK1,OR2W3,ZNF391,PGBD5,PNRC1,CAPN5,TTC22,PLEKHA1,SGK2,NT5DC2,PLEKHB1,DYRK1B,SPNS1,TCF7L1,ERN1,APBA2,GPR63,LONRF1,RGS16,RUNX2,ZNF395,BVES,FBXO4,UBASH3B,CYP4V2,RASL11B,SETBP1,CHADL,SATB1,FHOD3,NUMBL,SLC30A4,GAN,EBF4,BNIP3,NCEH1,VGLL4,BARX1,IL17RD,SPATA13,EFNA3,MAFB,STRADB,WWC1,WDR25,PPFIA4,LHPP,PRDM1,B4GALNT3,KIAA0355,HK2,RNF122,DOCK1,RHPN2,KIF21B,RADIL,CBLN1,KCTD15,RPS6KL1,EEPD1,ZDHHC23,ZNF521,MAP7,MYH15,TMEM120B,HSPA2,FAM78B,PHLDB2,UROS,PTPN6,SLC39A8,JAM3,CENPV,IFT81,LMLN,ANKRD31,RBPMS2,DISP1,NECAB2,PRSS16,ARHGEF11,BLVRB,OVOL2,RASD2,EHD3,PRKCD,GTF2F2,PRICKLE2,TRIM3,SGK1,CCDC122,ACTA2,KIAA0408,MSX1,NUAK2,OGDHL,EXOG,PALLD,TLR6,CTIF,RERE,FMO4,MAP2K6,KIAA0513,THAP10,RNF157,PKIA |
| 5.786e-05 | -9.76 | haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-diffuse_large_B_cell_lymphoma | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-diffuse_large_B_cell_lymphoma | 3717 | 88 | 17385 | 281 |
ZNF516,DUSP8,LGR4,RASAL2,DOCK1,ST14,CCDC110,PTPN21,PLXNA2,RHPN2,ITPR2,ABAT,PRKCA,KIF21B,RADIL,HMCN1,TIAM2,FKBP9,PPM1E,KMO,ZNF521,EEPD1,MYH15,TLN2,DNAH5,TMEM120B,FANK1,ATP6AP1L,PGBD5,C3orf67,DZANK1,CAPN5,NLGN4X,SATB2,RAB38,TBC1D16,JAM3,IQCK,TCF7L1,RBPMS2,RASGRF2,WWTR1,PLEKHG1,P4HA1,TANC2,COBL,CCDC148,MXI1,NECAB2,ARHGEF11,BACE1,SETBP1,SLC36A4,DYNC1I1,FHOD3,MTUS1,NEO1,RALGPS2,SLC30A4,MYC,SRGAP1,PRICKLE2,SGK1,MOXD1,VGLL4,GPR161,EPB41L5,B9D1,MN1,BDNF,OGDHL,SPATA13,WDR25,LHPP,PRDM1,PALLD,GPR137C,RERE,CTIF,GPLD1,KIAA0355,ADAMTS3,ISM1,GNAO1,MAP2K6,LRRIQ3,MYOM2,ZNF474 |
| 6.045e-05 | -9.71 | MSX2 (msh homeobox 2) | protein interactions | 4488 | 26 | 5 | 17029 | 283 |
CEBPA,MSX1,DLX2,RUNX2,GTF2F2 |
| 6.582e-05 | -9.63 | positive regulation of molecular function | biological process | GO:0044093 | 1736 | 48 | 17256 | 270 |
ARHGAP26,RGS16,ACSL1,RASAL2,ARHGEF11,DOCK1,GAS6,DYNC1I1,PFN2,TIAM2,RGS17,PMAIP1,DACT1,MYC,PRKCD,EHD3,SRGAP1,SGK1,INAVA,DAB2IP,EPHB6,TSHR,FANK1,HSPA2,PARP9,TBC1D8,EPB41L5,BDNF,ADCY1,EFNA3,STRADB,WNT11,ACVR2B,SAV1,ARRDC4,SGK2,TBC1D16,TLR6,GPLD1,TRIB3,FGR,PLK2,MAP2K6,GNAO1,ERN1,ARHGAP28,TNFSF15,DDIT3 |
| 6.942e-05 | -9.58 | GSE16451_CTRL_VS_WEST_EQUINE_ENC_VIRUS_MATURE_NEURON_CELL_LINE_DN | MSigDB lists | GSE16451_CTRL_VS_WEST_EQUINE_ENC_VIRUS_MATURE_NEURON_CELL_LINE_DN | 191 | 12 | 17377 | 282 |
LONRF1,RECK,DSTN,ZDHHC23,MAP7,P4HA1,CEBPA,NRN1,SAV1,ARRDC4,ABHD4,GPLD1 |
| 7.152e-05 | -9.55 | GROSS_HYPOXIA_VIA_ELK3_AND_HIF1A_UP | MSigDB lists | GROSS_HYPOXIA_VIA_ELK3_AND_HIF1A_UP | 135 | 10 | 17377 | 282 |
RGS16,MXI1,PDK1,PNRC1,PLK2,HK2,SGK1,P4HA1,BNIP3,PALLD |
| 7.214e-05 | -9.54 | hepatocellular_carcinoma | COSMIC cancer mutations | hepatocellular_carcinoma | 15259 | 266 | 17385 | 281 |
ARHGAP26,ACVR1,DUSP8,LGR4,RECK,LSM11,ALG1L,CEBPA,PRKCA,ABHD6,NCS1,EPDR1,PMAIP1,CFHR1,TMEM37,TSHR,TBC1D8,KLHL23,KLHL3,WISP3,EXOC6B,DSTN,BNIP3L,SLC25A28,ABCC2,TNS1,ACVR2B,SAV1,SPATA9,PLK2,RASGRF2,ALDOA,ARHGAP28,MAPK13,TMOD2,TANC2,SCN5A,TMEM63C,ZHX3,CYP2J2,SLC36A4,TNFRSF10C,DYNC1I1,HPCAL4,NIPSNAP3B,MTUS1,RALGPS2,MYC,ZIC5,SRGAP1,MOXD1,STXBP1,GPR161,EPB41L5,BDNF,QSOX1,SHISA2,ARRDC4,OR11H4,ZNF558,ADAMTS3,ISM1,LRRIQ3,QPCTL,EMILIN2,CLMN,IQSEC2,SMYD3,ZNF516,RASAL2,ST14,C4A,FAM131C,CCDC110,PLXNA2,COLEC10,TIAM2,TMEM53,ZNF827,KMO,DACT1,DAB2IP,PJA1,PDE4D,RAB27B,DNAH5,ATP6AP1L,C3orf67,DZANK1,GAPDH,PDK1,SOX21,CYB5R2,SFXN4,ADCY1,NLGN4X,SATB2,RAB38,TBC1D16,IQCK,WFS1,WWTR1,PLEKHG1,P4HA1,TNFSF15,DBP,KLHL31,COBL,C2orf88,CCDC148,MXI1,TMEM132C,BACE1,BIK,CCNJL,KIF5C,ARL2,ZNF219,NEO1,GPR155,SMPDL3A,PARP9,TMC7,MN1,B9D1,SLC40A1,PXN,MPP1,GPR137C,GPLD1,TRIB3,FGR,GNAO1,MYOM2,DDIT3,B4GALT7,PHC1,CCDC126,ACSL1,HEBP1,PTPN21,NDRG2,ABAT,ITPR2,SLC2A13,CACNB4,ABHD4,HMCN1,EPCAM,PPM1E,FKBP9,MARVELD2,DLX6,TMEM143,TLN2,FANK1,OR2W3,ZNF391,PGBD5,CAPN5,ATOX1,TTC22,PLEKHA1,SGK2,NT5DC2,PLEKHB1,DYRK1B,SPNS1,TCF7L1,ERN1,DLX2,APBA2,GPR63,LONRF1,RGS16,RUNX2,ZNF395,BVES,SCART1,FBXO4,UBASH3B,CYP4V2,ATP6V1E2,RASL11B,SETBP1,CHADL,SATB1,PFN2,FHOD3,NUMBL,SLC30A4,GAN,EBF4,NCEH1,VGLL4,BARX1,IL17RD,SPATA13,EFNA3,MAFB,STRADB,WWC1,WDR25,PPFIA4,LHPP,PRDM1,B4GALNT3,KIAA0355,HK2,RNF122,DOCK1,RHPN2,FAM198B,KIF21B,RADIL,CBLN1,KCTD15,RPS6KL1,EEPD1,ZDHHC23,ZNF521,MAP7,MYH15,TMEM120B,HSPA2,FAM78B,PHLDB2,UROS,PTPN6,SLC39A8,JAM3,CENPV,IFT81,LMLN,ANKRD31,RBPMS2,DISP1,NECAB2,PRSS16,ARHGEF11,BLVRB,OVOL2,RASD2,EHD3,PRKCD,GTF2F2,ACTA2,PRICKLE2,TRIM3,SGK1,CCDC122,KIAA0408,MSX1,NUAK2,OGDHL,EXOG,PALLD,TLR6,CTIF,RERE,FMO4,MAP2K6,KIAA0513,ZNF474,RNF157,PKIA |
| 7.214e-05 | -9.54 | liver-carcinoma-hepatocellular_carcinoma | COSMIC cancer mutations | liver-carcinoma-hepatocellular_carcinoma | 15259 | 266 | 17385 | 281 |
ARHGAP26,ACVR1,DUSP8,LGR4,RECK,LSM11,ALG1L,CEBPA,PRKCA,ABHD6,NCS1,EPDR1,PMAIP1,CFHR1,TMEM37,TSHR,TBC1D8,KLHL23,KLHL3,WISP3,EXOC6B,DSTN,BNIP3L,SLC25A28,ABCC2,TNS1,ACVR2B,SAV1,SPATA9,PLK2,RASGRF2,ALDOA,ARHGAP28,MAPK13,TMOD2,TANC2,SCN5A,TMEM63C,ZHX3,CYP2J2,SLC36A4,TNFRSF10C,DYNC1I1,HPCAL4,NIPSNAP3B,MTUS1,RALGPS2,MYC,ZIC5,SRGAP1,MOXD1,STXBP1,GPR161,EPB41L5,BDNF,QSOX1,SHISA2,ARRDC4,OR11H4,ZNF558,ADAMTS3,ISM1,LRRIQ3,QPCTL,EMILIN2,CLMN,IQSEC2,SMYD3,ZNF516,RASAL2,ST14,C4A,FAM131C,CCDC110,PLXNA2,COLEC10,TIAM2,TMEM53,ZNF827,KMO,DACT1,DAB2IP,PJA1,PDE4D,RAB27B,DNAH5,ATP6AP1L,C3orf67,DZANK1,GAPDH,PDK1,SOX21,CYB5R2,SFXN4,ADCY1,NLGN4X,SATB2,RAB38,TBC1D16,IQCK,WFS1,WWTR1,PLEKHG1,P4HA1,TNFSF15,DBP,KLHL31,COBL,C2orf88,CCDC148,MXI1,TMEM132C,BACE1,BIK,CCNJL,KIF5C,ARL2,ZNF219,NEO1,GPR155,SMPDL3A,PARP9,TMC7,MN1,B9D1,SLC40A1,PXN,MPP1,GPR137C,GPLD1,TRIB3,FGR,GNAO1,MYOM2,DDIT3,B4GALT7,PHC1,CCDC126,ACSL1,HEBP1,PTPN21,NDRG2,ABAT,ITPR2,SLC2A13,CACNB4,ABHD4,HMCN1,EPCAM,PPM1E,FKBP9,MARVELD2,DLX6,TMEM143,TLN2,FANK1,OR2W3,ZNF391,PGBD5,CAPN5,ATOX1,TTC22,PLEKHA1,SGK2,NT5DC2,PLEKHB1,DYRK1B,SPNS1,TCF7L1,ERN1,DLX2,APBA2,GPR63,LONRF1,RGS16,RUNX2,ZNF395,BVES,SCART1,FBXO4,UBASH3B,CYP4V2,ATP6V1E2,RASL11B,SETBP1,CHADL,SATB1,PFN2,FHOD3,NUMBL,SLC30A4,GAN,EBF4,NCEH1,VGLL4,BARX1,IL17RD,SPATA13,EFNA3,MAFB,STRADB,WWC1,WDR25,PPFIA4,LHPP,PRDM1,B4GALNT3,KIAA0355,HK2,RNF122,DOCK1,RHPN2,FAM198B,KIF21B,RADIL,CBLN1,KCTD15,RPS6KL1,EEPD1,ZDHHC23,ZNF521,MAP7,MYH15,TMEM120B,HSPA2,FAM78B,PHLDB2,UROS,PTPN6,SLC39A8,JAM3,CENPV,IFT81,LMLN,ANKRD31,RBPMS2,DISP1,NECAB2,PRSS16,ARHGEF11,BLVRB,OVOL2,RASD2,EHD3,PRKCD,GTF2F2,ACTA2,PRICKLE2,TRIM3,SGK1,CCDC122,KIAA0408,MSX1,NUAK2,OGDHL,EXOG,PALLD,TLR6,CTIF,RERE,FMO4,MAP2K6,KIAA0513,ZNF474,RNF157,PKIA |
| 7.561e-05 | -9.49 | lung-carcinoid-endocrine_tumour | COSMIC cancer mutations | lung-carcinoid-endocrine_tumour | 504 | 21 | 17385 | 281 |
ACVR1,LGR4,PDK1,NUAK2,STRADB,CEBPA,ACVR2B,SGK2,PRKCA,DYRK1B,TRIB3,FGR,PLK2,RPS6KL1,MAP2K6,PRKCD,ERN1,SGK1,MAPK13,TANC2,TBC1D8 |
| 7.627e-05 | -9.48 | STK33_SKM_UP | MSigDB lists | STK33_SKM_UP | 255 | 14 | 17377 | 282 |
EPB41L5,FGR,DUSP8,KMO,PLK2,SETBP1,MAFB,SGK1,ACTA2,TMOD2,PALLD,GPR137C,TLR6,TBC1D8 |
| 8.179e-05 | -9.41 | GSE21360_NAIVE_VS_PRIMARY_MEMORY_CD8_TCELL_UP | MSigDB lists | GSE21360_NAIVE_VS_PRIMARY_MEMORY_CD8_TCELL_UP | 165 | 11 | 17377 | 282 |
QSOX1,CPNE2,PDK1,EMILIN2,HK2,ZDHHC23,MAFB,P4HA1,GAS6,PDE4D,VGLL4 |
| 9.374e-05 | -9.27 | GO_INTRINSIC_APOPTOTIC_SIGNALING_PATHWAY_IN_RESPONSE_TO_ENDOPLASMIC_RETICULUM_STRESS | MSigDB lists | GO_INTRINSIC_APOPTOTIC_SIGNALING_PATHWAY_IN_RESPONSE_TO_ENDOPLASMIC_RETICULUM_STRESS | 29 | 5 | 17377 | 282 |
TRIB3,DAB2IP,PMAIP1,DDIT3,ERN1 |
| 9.404e-05 | -9.27 | LEONARD_HYPOXIA | MSigDB lists | LEONARD_HYPOXIA | 46 | 6 | 17377 | 282 |
P4HA1,BNIP3,MXI1,ALDOA,DDIT3,HK2 |
| 9.814e-05 | -9.23 | digestive tract morphogenesis | biological process | GO:0048546 | 48 | 6 | 17256 | 270 |
EPB41L5,WNT11,ACVR2B,OVOL2,DACT1,RBPMS2 |
| 1.028e-04 | -9.18 | MANALO_HYPOXIA_UP | MSigDB lists | MANALO_HYPOXIA_UP | 199 | 12 | 17377 | 282 |
MN1,FKBP9,TCF7L1,MXI1,PXN,ZNF395,BNIP3L,P4HA1,TNS1,BNIP3,GAS6,ITPR2 |
| 1.059e-04 | -9.15 | GO_REGULATION_OF_PLATELET_AGGREGATION | MSigDB lists | GO_REGULATION_OF_PLATELET_AGGREGATION | 16 | 4 | 17377 | 282 |
ABAT,PRKCA,UBASH3B,PRKCD |
| 1.086e-04 | -9.13 | PH_domain | interpro domains | IPR001849 | 267 | 14 | 18492 | 296 |
ARHGAP26,PHLDB2,RASAL2,RALGPS2,ARHGEF11,RASGRF2,SPATA13,PLEKHG1,DAB2IP,PLEKHA1,IQSEC2,GRK3,TIAM2,PLEKHB1 |
| 1.188e-04 | -9.04 | regulation of platelet aggregation | biological process | GO:0090330 | 17 | 4 | 17256 | 270 |
ABAT,PRKCA,UBASH3B,PRKCD |
| 1.221e-04 | -9.01 | positive regulation of biological process | biological process | GO:0048518 | 5677 | 118 | 17256 | 270 |
ACSL1,ZNF516,ACVR1,LGR4,DOCK1,C4A,LSM11,PLXNA2,CEBPA,ABAT,COLEC10,PRKCA,ABHD6,CBLN1,TIAM2,NCS1,EPCAM,PPM1E,PMAIP1,KMO,DACT1,DLX6,CFHR1,DAB2IP,PDE4D,EPHB6,RAB27B,TSHR,FANK1,HSPA2,TBC1D8,PHLDB2,GAPDH,SOX21,PTPN6,DSTN,BNIP3L,ADCY1,SATB2,WNT11,PXYLP1,ACVR2B,PLEKHA1,SGK2,SAV1,CENPV,DYRK1B,RASGRF2,PLK2,WFS1,RBPMS2,ERN1,WWTR1,TNFSF15,MAPK13,TMOD2,DISP1,DBP,DLX2,COBL,LONRF1,SCN5A,RUNX2,NECAB2,BVES,ARHGEF11,ZHX3,FBXO4,BIK,ARL2,SLX1B,GAS6,OVOL2,TNFRSF10C,ZNF219,PFN2,MYORG,NEO1,IL17D,KDM7A,NUMBL,MYC,PRKCD,EHD3,RASD2,GTF2F2,EBF4,ACTA2,SGK1,INAVA,BNIP3,STXBP1,BARX1,GPR161,PARP9,EPB41L5,SLC40A1,ENAM,BDNF,PXN,MSX1,EFNA3,WWC1,STRADB,MAFB,GAREM1,PRDM1,ARRDC4,TLR6,RERE,GPLD1,TRIB3,FGR,ADAMTS3,MAP2K6,HK2,SMYD3,DDIT3 |
| 1.299e-04 | -8.95 | GO_DIGESTIVE_SYSTEM_DEVELOPMENT | MSigDB lists | GO_DIGESTIVE_SYSTEM_DEVELOPMENT | 145 | 10 | 17377 | 282 |
EPB41L5,LGR4,DACT1,WNT11,PRDM1,OVOL2,ACVR2B,SAV1,BARX1,COBL |
| 1.368e-04 | -8.90 | SARTIPY_BLUNTED_BY_INSULIN_RESISTANCE_DN | MSigDB lists | SARTIPY_BLUNTED_BY_INSULIN_RESISTANCE_DN | 17 | 4 | 17377 | 282 |
TRIB3,DBP,ACVR1,RERE |
| 1.394e-04 | -8.88 | regulation of cell communication | biological process | GO:0010646 | 3548 | 81 | 17256 | 270 |
ARHGAP26,ACVR1,DUSP8,LGR4,RASAL2,NDRG2,ITPR2,ABAT,PRKCA,ABHD6,CBLN1,TIAM2,PMAIP1,KMO,DACT1,DAB2IP,PDE4D,EPHB6,WISP3,PTPN6,NLGN4X,WNT11,ACVR2B,PLEKHA1,TCF7L1,RASGRF2,PLK2,WFS1,RBPMS2,ERN1,WWTR1,PLEKHG1,ARHGAP28,TNFSF15,TMOD2,DISP1,DLX2,RGS16,NECAB2,RUNX2,ARHGEF11,UBASH3B,BACE1,BIK,ARL2,RASL11B,GAS6,TNFRSF10C,PFN2,MYORG,NEO1,IL17D,RGS17,RALGPS2,MYC,PRKCD,RASD2,SRGAP1,INAVA,BNIP3,STXBP1,BARX1,GPR161,PARP9,BDNF,MSX1,PXN,SPATA13,WWC1,STRADB,SHISA2,GAREM1,PRDM1,TLR6,GPLD1,TRIB3,FGR,ADAMTS3,MAP2K6,IQSEC2,DDIT3 |
| 1.441e-04 | -8.85 | anatomical structure morphogenesis | biological process | GO:0009653 | 2047 | 53 | 17256 | 270 |
SCN5A,ACVR1,RUNX2,LGR4,ST14,BVES,RECK,PLXNA2,KIF5C,OVOL2,PRKCA,ZNF219,RADIL,CBLN1,FHOD3,NEO1,NUMBL,DLX6,DACT1,MYC,ACTA2,SGK1,DAB2IP,STXBP1,EPB41L5,B9D1,BDNF,ENAM,SLC40A1,MSX1,KLHL3,PTPN6,EFNA3,ADCY1,STRADB,MAFB,SATB2,WNT11,PRDM1,ACVR2B,PLEKHA1,SAV1,PALLD,JAM3,GPLD1,RERE,DYRK1B,RBPMS2,WWTR1,TMOD2,MYOM2,DLX2,COBL |
| 1.493e-04 | -8.81 | Pkinase | pfam domains | PF00069 | 348 | 16 | 17054 | 271 |
ACVR1,NUAK2,STRADB,ACVR2B,PRKCA,SGK2,GRK3,DYRK1B,TRIB3,PLK2,RPS6KL1,MAP2K6,ERN1,PRKCD,SGK1,MAPK13 |
| 1.498e-04 | -8.81 | BATF2 (basic leucine zipper ATF-like transcription factor 2) | protein interactions | 116071 | 17 | 4 | 17029 | 283 |
C2orf88,CEBPA,DBP,DDIT3 |
| 1.507e-04 | -8.80 | YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_0 | MSigDB lists | YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_0 | 71 | 7 | 17377 | 282 |
BNIP3,MXI1,DBP,PNRC1,RECK,SMPDL3A,CYP4V2 |
| 1.509e-04 | -8.80 | central_nervous_system-brain-glioma-astrocytoma_Grade_III | COSMIC cancer mutations | central_nervous_system-brain-glioma-astrocytoma_Grade_III | 1449 | 42 | 17385 | 281 |
ARHGAP26,CCDC148,ZNF516,RASAL2,DOCK1,BLVRB,SETBP1,ARL2,PRKCA,ABHD4,DYNC1I1,HMCN1,FHOD3,ZNF827,FKBP9,RALGPS2,MARVELD2,RPS6KL1,GTF2F2,MAP7,TRIM3,MYH15,MOXD1,TLN2,DNAH5,OR2W3,PGBD5,MN1,QSOX1,PHLDB2,EXOC6B,WDR25,SGK2,GPLD1,ADAMTS3,PLK2,MAP2K6,EMILIN2,TNFSF15,TANC2,COBL,B4GALT7 |
| 1.513e-04 | -8.80 | NECAB3 (N-terminal EF-hand calcium binding protein 3) | protein interactions | 63941 | 7 | 3 | 17029 | 283 |
NECAB2,APBA2,MYC |
| 1.528e-04 | -8.79 | FARDIN_HYPOXIA_11 | MSigDB lists | FARDIN_HYPOXIA_11 | 32 | 5 | 17377 | 282 |
BNIP3,MXI1,PDK1,ZNF395,BNIP3L |
| 1.541e-04 | -8.78 | ovary-carcinoma | COSMIC cancer mutations | ovary-carcinoma | 948 | 31 | 17385 | 281 |
BDNF,ACVR1,PDK1,RECK,BACE1,NUAK2,STRADB,ARL2,SATB2,ABCC2,PRDM1,ITPR2,ACVR2B,SGK2,PRKCA,HMCN1,DYRK1B,TCF7L1,TRIB3,FGR,PLK2,MAP2K6,RPS6KL1,PRKCD,ERN1,ZNF521,SGK1,MAPK13,MOXD1,DNAH5,FANK1 |
| 1.588e-04 | -8.75 | positive regulation of cellular process | biological process | GO:0048522 | 5055 | 107 | 17256 | 270 |
ACSL1,ZNF516,ACVR1,LGR4,DOCK1,C4A,LSM11,PLXNA2,CEBPA,ABAT,PRKCA,CBLN1,TIAM2,NCS1,EPCAM,PPM1E,PMAIP1,KMO,DACT1,DLX6,CFHR1,DAB2IP,EPHB6,RAB27B,TSHR,FANK1,HSPA2,TBC1D8,PHLDB2,GAPDH,SOX21,PTPN6,DSTN,BNIP3L,ADCY1,SATB2,WNT11,PXYLP1,ACVR2B,SAV1,CENPV,DYRK1B,RASGRF2,PLK2,WFS1,RBPMS2,ERN1,WWTR1,TNFSF15,TMOD2,DISP1,DBP,DLX2,COBL,LONRF1,SCN5A,RUNX2,NECAB2,BVES,ARHGEF11,ZHX3,FBXO4,BIK,ARL2,SLX1B,GAS6,OVOL2,TNFRSF10C,ZNF219,PFN2,MYORG,NEO1,KDM7A,NUMBL,MYC,PRKCD,RASD2,GTF2F2,EBF4,INAVA,BNIP3,STXBP1,BARX1,GPR161,PARP9,EPB41L5,SLC40A1,BDNF,PXN,MSX1,EFNA3,WWC1,STRADB,MAFB,GAREM1,PRDM1,ARRDC4,TLR6,RERE,GPLD1,TRIB3,FGR,ADAMTS3,MAP2K6,HK2,SMYD3,DDIT3 |
| 1.604e-04 | -8.74 | brainstem | COSMIC cancer mutations | brainstem | 3173 | 76 | 17385 | 281 |
ARHGAP26,ZNF516,ACVR1,RASAL2,DOCK1,ST14,FAM131C,PTPN21,PLXNA2,RHPN2,ITPR2,COLEC10,PRKCA,ABHD6,HMCN1,TIAM2,FKBP9,ZNF827,PPM1E,KMO,ZNF521,MAP7,MYH15,TSHR,FAM78B,ATP6AP1L,KIAA1549,PGBD5,C3orf67,UROS,PTPN6,ADCY1,NLGN4X,SLC25A28,SATB2,TNS1,ABCC2,SGK2,TCF7L1,LMLN,RBPMS2,RASGRF2,ARHGAP28,DLX2,KLHL31,COBL,SCN5A,ARHGEF11,BACE1,UBASH3B,CYP4V2,DYNC1I1,SATB1,FHOD3,RGS17,GPR155,RASD2,SRGAP1,PRICKLE2,BARX1,SMPDL3A,PARP9,TMC7,OGDHL,WDR25,SHISA2,LHPP,PALLD,RERE,CTIF,KIAA0355,ADAMTS3,EMILIN2,LRRIQ3,CLMN,MYOM2 |
| 1.605e-04 | -8.74 | ERB2_UP.V1_UP | MSigDB lists | ERB2_UP.V1_UP | 178 | 11 | 17377 | 282 |
PNRC1,UROS,KMO,CAPN5,BNIP3L,KIAA0513,CLMN,PDE4D,HSPA2,PLEKHB1,TBC1D8 |
| 1.656e-04 | -8.71 | LIM_MAMMARY_STEM_CELL_UP | MSigDB lists | LIM_MAMMARY_STEM_CELL_UP | 454 | 19 | 17377 | 282 |
IL17RD,MSX1,PXN,BVES,RECK,PLXNA2,TNS1,PRDM1,ZNF219,CACNB4,JAM3,FHOD3,EPDR1,TCF7L1,MYC,ISM1,EEPD1,ACTA2,PRICKLE2 |
| 1.884e-04 | -8.58 | ROVERSI_GLIOMA_COPY_NUMBER_DN | MSigDB lists | ROVERSI_GLIOMA_COPY_NUMBER_DN | 52 | 6 | 17377 | 282 |
GPR63,CPNE2,UROS,FANK1,DOCK1,GNAO1 |
| 1.950e-04 | -8.54 | GSE22886_NAIVE_CD4_TCELL_VS_MONOCYTE_UP | MSigDB lists | GSE22886_NAIVE_CD4_TCELL_VS_MONOCYTE_UP | 182 | 11 | 17377 | 282 |
KIF5C,BNIP3,PLEKHA1,PJA1,PDE4D,KIF21B,PRKCA,KLHL3,SMYD3,PLEKHB1,PKIA |
| 2.002e-04 | -8.52 | negative regulation of glial cell apoptotic process | biological process | GO:0034351 | 8 | 3 | 17256 | 270 |
GAS6,PRKCA,PRKCD |
| 2.002e-04 | -8.52 | negative regulation of mitochondrial membrane potential | biological process | GO:0010917 | 8 | 3 | 17256 | 270 |
BNIP3,PMAIP1,BNIP3L |
| 2.068e-04 | -8.48 | GO_NUCLEOSIDE_TRIPHOSPHATASE_REGULATOR_ACTIVITY | MSigDB lists | GO_NUCLEOSIDE_TRIPHOSPHATASE_REGULATOR_ACTIVITY | 315 | 15 | 17377 | 282 |
ARHGAP26,RGS17,RGS16,RASAL2,ARHGEF11,DOCK1,SRGAP1,ARHGAP28,ARL2,WNT11,DAB2IP,PFN2,TBC1D16,TIAM2,TBC1D8 |
| 2.077e-04 | -8.48 | CBY1 (chibby family member 1, beta catenin antagonist) | protein interactions | 25776 | 150 | 10 | 17029 | 283 |
NUMBL,PHLDB2,FKBP9,RALGPS2,RASAL2,GAN,MAP7,KIF5C,DAB2IP,TANC2 |
| 2.081e-04 | -8.48 | ZHANG_RESPONSE_TO_IKK_INHIBITOR_AND_TNF_DN | MSigDB lists | ZHANG_RESPONSE_TO_IKK_INHIBITOR_AND_TNF_DN | 99 | 8 | 17377 | 282 |
MN1,TMEM53,BDNF,KCTD15,ZNF395,LGR4,RASL11B,MTUS1 |
| 2.121e-04 | -8.46 | MODULE_47 | MSigDB lists | MODULE_47 | 215 | 12 | 17377 | 282 |
RGS16,CFHR1,WWTR1,ZNF521,ACTA2,P4HA1,NRN1,GAS6,MOXD1,PALLD,VGLL4,JAM3 |
| 2.160e-04 | -8.44 | ELVIDGE_HYPOXIA_BY_DMOG_UP | MSigDB lists | ELVIDGE_HYPOXIA_BY_DMOG_UP | 126 | 9 | 17377 | 282 |
QSOX1,MXI1,PDK1,ZNF395,HK2,BNIP3L,P4HA1,BNIP3,PRKCA |
| 2.243e-04 | -8.40 | GSE11057_NAIVE_VS_CENT_MEMORY_CD4_TCELL_UP | MSigDB lists | GSE11057_NAIVE_VS_CENT_MEMORY_CD4_TCELL_UP | 155 | 10 | 17377 | 282 |
PDK1,SFXN4,DACT1,MPP1,BNIP3L,BNIP3,SGK2,APBA2,SATB1,CENPV |
| 2.356e-04 | -8.35 | GSE22935_WT_VS_MYD88_KO_MACROPHAGE_48H_MBOVIS_BCG_STIM_UP | MSigDB lists | GSE22935_WT_VS_MYD88_KO_MACROPHAGE_48H_MBOVIS_BCG_STIM_UP | 186 | 11 | 17377 | 282 |
ACSL1,KLHL23,BVES,DACT1,RASGRF2,WFS1,DAB2IP,MYOM2,TLN2,PALLD,COBL |
| 2.356e-04 | -8.35 | GSE20715_0H_VS_24H_OZONE_TLR4_KO_LUNG_UP | MSigDB lists | GSE20715_0H_VS_24H_OZONE_TLR4_KO_LUNG_UP | 186 | 11 | 17377 | 282 |
EPB41L5,RALGPS2,RASD2,SPATA13,TMEM143,PRDM1,ACVR2B,DBP,FAM198B,SATB1,RERE |
| 2.389e-04 | -8.34 | GO_TRANSITION_METAL_ION_HOMEOSTASIS | MSigDB lists | GO_TRANSITION_METAL_ION_HOMEOSTASIS | 101 | 8 | 17377 | 282 |
SLC40A1,SLC30A4,SLC39A8,SFXN4,MYC,ATOX1,SLC25A28,NEO1 |
| 2.439e-04 | -8.32 | hematopoietic stem cell migration to bone marrow | biological process | GO:0097241 | 2 | 2 | 17256 | 270 |
GAS6,GPLD1 |
| 2.468e-04 | -8.31 | GSE24634_TEFF_VS_TCONV_DAY7_IN_CULTURE_DN | MSigDB lists | GSE24634_TEFF_VS_TCONV_DAY7_IN_CULTURE_DN | 187 | 11 | 17377 | 282 |
QSOX1,FGR,PLK2,PRKCD,ATOX1,KIAA0513,SGK1,TNS1,CEBPA,PLEKHA1,SAV1 |
| 2.475e-04 | -8.30 | central_nervous_system-brainstem-glioma-astrocytoma_Grade_IV | COSMIC cancer mutations | central_nervous_system-brainstem-glioma-astrocytoma_Grade_IV | 2583 | 64 | 17385 | 281 |
ARHGAP26,ZNF516,ACVR1,RASAL2,DOCK1,ST14,PTPN21,PLXNA2,RHPN2,ITPR2,COLEC10,PRKCA,ABHD6,HMCN1,FKBP9,ZNF827,PPM1E,KMO,ZNF521,MAP7,MYH15,FAM78B,ATP6AP1L,PGBD5,C3orf67,UROS,ADCY1,NLGN4X,SLC25A28,TNS1,ABCC2,SGK2,TCF7L1,LMLN,RBPMS2,RASGRF2,ARHGAP28,DLX2,KLHL31,COBL,ARHGEF11,BACE1,UBASH3B,CYP4V2,DYNC1I1,SATB1,FHOD3,GPR155,RASD2,SRGAP1,PRICKLE2,BARX1,SMPDL3A,PARP9,WDR25,LHPP,PALLD,CTIF,RERE,KIAA0355,ADAMTS3,EMILIN2,LRRIQ3,MYOM2 |
| 2.516e-04 | -8.29 | ULD | pfam domains | PF16534 | 2 | 2 | 17054 | 271 |
SATB2,SATB1 |
| 2.516e-04 | -8.29 | BNIP3 | pfam domains | PF06553 | 2 | 2 | 17054 | 271 |
BNIP3,BNIP3L |
| 2.516e-04 | -8.29 | CUTL | pfam domains | PF16557 | 2 | 2 | 17054 | 271 |
SATB2,SATB1 |
| 2.554e-04 | -8.27 | SATB_ULD_sf | interpro domains | IPR038224 | 2 | 2 | 18492 | 296 |
SATB2,SATB1 |
| 2.554e-04 | -8.27 | BNIP3 | interpro domains | IPR010548 | 2 | 2 | 18492 | 296 |
BNIP3,BNIP3L |
| 2.554e-04 | -8.27 | CUTL | interpro domains | IPR032355 | 2 | 2 | 18492 | 296 |
SATB2,SATB1 |
| 2.554e-04 | -8.27 | SATB_CUTL_sf | interpro domains | IPR038216 | 2 | 2 | 18492 | 296 |
SATB2,SATB1 |
| 2.554e-04 | -8.27 | ULD | interpro domains | IPR032392 | 2 | 2 | 18492 | 296 |
SATB2,SATB1 |
| 2.653e-04 | -8.23 | haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-acute_lymphoblastic_leukaemia | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-acute_lymphoblastic_leukaemia | 2128 | 55 | 17385 | 281 |
ACVR1,ZNF395,LGR4,PRSS16,DOCK1,ST14,PTPN21,SETBP1,ATP6V1E2,CEBPA,FAM198B,PRKCA,KIF21B,DYNC1I1,HMCN1,TIAM2,FHOD3,FKBP9,RPS6KL1,ZIC5,PRKCD,ACTA2,SGK1,DAB2IP,MYH15,TLN2,DNAH5,OR2W3,HSPA2,GPR161,EPB41L5,TMC7,PDK1,NUAK2,PPFIA4,STRADB,WWC1,TNS1,ABCC2,ACVR2B,SGK2,SAV1,B4GALNT3,TBC1D16,GPLD1,SPNS1,DYRK1B,TRIB3,FGR,KIAA0355,PLK2,MAP2K6,ERN1,MAPK13,COBL |
| 2.705e-04 | -8.22 | GSE19198_1H_VS_24H_IL21_TREATED_TCELL_UP | MSigDB lists | GSE19198_1H_VS_24H_IL21_TREATED_TCELL_UP | 189 | 11 | 17377 | 282 |
SLC40A1,MSX1,BVES,RECK,RASD2,PRKCD,ZNF521,MAFB,DBP,FAM198B,SMPDL3A |
| 2.725e-04 | -8.21 | PH | smart domains | SM00233 | 261 | 14 | 9493 | 172 |
ARHGAP26,PHLDB2,RASAL2,RALGPS2,ARHGEF11,RASGRF2,SPATA13,PLEKHG1,DAB2IP,PLEKHA1,IQSEC2,GRK3,TIAM2,PLEKHB1 |
| 2.831e-04 | -8.17 | GSE29618_MONOCYTE_VS_PDC_UP | MSigDB lists | GSE29618_MONOCYTE_VS_PDC_UP | 190 | 11 | 17377 | 282 |
FGR,GAPDH,ACSL1,PXN,HEBP1,BLVRB,HK2,BNIP3L,MAFB,CEBPA,FAM198B |
| 2.831e-04 | -8.17 | GSE17721_LPS_VS_CPG_8H_BMDC_UP | MSigDB lists | GSE17721_LPS_VS_CPG_8H_BMDC_UP | 190 | 11 | 17377 | 282 |
IFT81,MXI1,PNRC1,GPR155,CAPN5,NDRG2,MAPK13,PRDM1,TLR6,HSPA2,BARX1 |
| 2.923e-04 | -8.14 | pancreas-carcinoma | COSMIC cancer mutations | pancreas-carcinoma | 15226 | 264 | 17385 | 281 |
ARHGAP26,ACVR1,DUSP8,LGR4,RECK,LSM11,ALG1L,CEBPA,PRKCA,ABHD6,NCS1,EPDR1,PMAIP1,CFHR1,TMEM37,TSHR,TBC1D8,KLHL23,KLHL3,WISP3,EXOC6B,DSTN,BNIP3L,SLC25A28,ABCC2,TNS1,ACVR2B,SAV1,SPATA9,PLK2,RASGRF2,ALDOA,ARHGAP28,MAPK13,TMOD2,TANC2,SCN5A,TMEM63C,ZHX3,CYP2J2,SLC36A4,TNFRSF10C,DYNC1I1,NIPSNAP3B,MTUS1,IL17D,RALGPS2,MYC,ZIC5,SRGAP1,MOXD1,STXBP1,GPR161,EPB41L5,BDNF,QSOX1,SHISA2,ARRDC4,OR11H4,ZNF558,ADAMTS3,ISM1,LRRIQ3,QPCTL,EMILIN2,CLMN,IQSEC2,ZNF516,RASAL2,ST14,FAM131C,CCDC110,PLXNA2,COLEC10,TIAM2,TMEM53,ZNF827,KMO,DACT1,DAB2IP,PDE4D,RAB27B,DNAH5,ATP6AP1L,C3orf67,DZANK1,GAPDH,PDK1,SOX21,CYB5R2,SFXN4,ADCY1,NLGN4X,SATB2,WNT11,RAB38,TBC1D16,TRIQK,IQCK,WFS1,WWTR1,PLEKHG1,P4HA1,TNFSF15,DBP,KLHL31,COBL,KCTD1,CCDC148,MXI1,TMEM132C,BACE1,BIK,CCNJL,KIF5C,ARL2,ZNF219,NEO1,RGS17,GPR155,SMPDL3A,PARP9,TMC7,MN1,B9D1,SLC40A1,PXN,MPP1,GPR137C,GPLD1,TRIB3,FGR,GNAO1,MYOM2,TNFRSF17,DDIT3,B4GALT7,PHC1,CCDC126,ACSL1,HEBP1,PTPN21,NDRG2,NRN1,ABAT,ITPR2,SLC2A13,CACNB4,ABHD4,HMCN1,EPCAM,PPM1E,FKBP9,CPNE2,MARVELD2,DLX6,TMEM143,TLN2,FANK1,OR2W3,PGBD5,CAPN5,ATOX1,PLEKHA1,SGK2,PLEKHB1,NT5DC2,DYRK1B,SPNS1,TCF7L1,ERN1,DLX2,APBA2,GPR63,LONRF1,RGS16,RUNX2,ZNF395,BVES,SCART1,FBXO4,UBASH3B,CYP4V2,RASL11B,SETBP1,CHADL,SATB1,FHOD3,NUMBL,SLC30A4,GAN,EBF4,BNIP3,NCEH1,VGLL4,BARX1,IL17RD,SPATA13,EFNA3,MAFB,STRADB,WWC1,WDR25,PPFIA4,LHPP,PRDM1,B4GALNT3,KIAA0355,HK2,RNF122,DOCK1,RHPN2,FAM198B,KIF21B,RADIL,KCTD15,RPS6KL1,EEPD1,ZDHHC23,ZNF521,MAP7,MYH15,TMEM120B,HSPA2,FAM78B,PHLDB2,UROS,PTPN6,SLC39A8,JAM3,CENPV,IFT81,LMLN,RBPMS2,DISP1,NECAB2,PRSS16,ARHGEF11,BLVRB,OVOL2,RASD2,EHD3,PRKCD,GTF2F2,PRICKLE2,TRIM3,SGK1,CCDC122,ACTA2,KIAA0408,MSX1,NUAK2,OGDHL,EXOG,PALLD,TLR6,CTIF,RERE,FMO4,MAP2K6,KIAA0513,THAP10,RNF157,PKIA |
| 2.961e-04 | -8.12 | GSE7460_FOXP3_MUT_VS_HET_ACT_TCONV_UP | MSigDB lists | GSE7460_FOXP3_MUT_VS_HET_ACT_TCONV_UP | 191 | 11 | 17377 | 282 |
EPB41L5,FKBP9,NUMBL,PXN,RUNX2,ADAMTS3,HEBP1,FAM198B,ABHD6,JAM3,B4GALT7 |
| 2.968e-04 | -8.12 | negative regulation of membrane potential | biological process | GO:0045837 | 9 | 3 | 17256 | 270 |
BNIP3,PMAIP1,BNIP3L |
| 2.968e-04 | -8.12 | regulation of glial cell apoptotic process | biological process | GO:0034350 | 9 | 3 | 17256 | 270 |
GAS6,PRKCA,PRKCD |
| 2.985e-04 | -8.12 | regulation of signal transduction | biological process | GO:0009966 | 3238 | 74 | 17256 | 270 |
ARHGAP26,ACVR1,DUSP8,LGR4,RASAL2,NDRG2,ABAT,PRKCA,ABHD6,CBLN1,TIAM2,PMAIP1,DACT1,DAB2IP,PDE4D,EPHB6,WISP3,PTPN6,NLGN4X,WNT11,ACVR2B,PLEKHA1,TCF7L1,PLK2,RASGRF2,WFS1,RBPMS2,ERN1,WWTR1,PLEKHG1,ARHGAP28,TNFSF15,TMOD2,DISP1,DLX2,RGS16,NECAB2,RUNX2,ARHGEF11,UBASH3B,BIK,RASL11B,TNFRSF10C,GAS6,MYORG,NEO1,IL17D,RGS17,RALGPS2,MYC,PRKCD,RASD2,SRGAP1,INAVA,BNIP3,BARX1,GPR161,PARP9,BDNF,MSX1,PXN,SPATA13,WWC1,STRADB,SHISA2,GAREM1,PRDM1,TLR6,TRIB3,FGR,ADAMTS3,MAP2K6,IQSEC2,DDIT3 |
| 3.020e-04 | -8.11 | ACEVEDO_FGFR1_TARGETS_IN_PROSTATE_CANCER_MODEL_DN | MSigDB lists | ACEVEDO_FGFR1_TARGETS_IN_PROSTATE_CANCER_MODEL_DN | 291 | 14 | 17377 | 282 |
CCDC126,RECK,ISM1,GNAO1,RBPMS2,ACTA2,NRN1,EPHB6,TLN2,TANC2,SATB1,KCTD1,FHOD3,PKIA |
| 3.145e-04 | -8.06 | - | gene3d domains | 3.10.20.710 | 2 | 2 | 8148 | 145 |
SATB2,SATB1 |
| 3.145e-04 | -8.06 | - | gene3d domains | 1.10.260.70 | 2 | 2 | 8148 | 145 |
SATB2,SATB1 |
| 3.149e-04 | -8.06 | diffuse_large_B_cell_lymphoma | COSMIC cancer mutations | diffuse_large_B_cell_lymphoma | 4283 | 95 | 17385 | 281 |
ZNF516,DUSP8,LGR4,RASAL2,DOCK1,ST14,CCDC110,PTPN21,PLXNA2,RHPN2,ITPR2,ABAT,PRKCA,KIF21B,RADIL,HMCN1,TIAM2,FKBP9,PPM1E,KMO,ZNF521,EEPD1,MYH15,TLN2,DNAH5,TMEM120B,FANK1,ATP6AP1L,PGBD5,C3orf67,DZANK1,EXOC6B,CAPN5,NLGN4X,SATB2,RAB38,TBC1D16,JAM3,IQCK,TCF7L1,WFS1,RBPMS2,RASGRF2,WWTR1,PLEKHG1,P4HA1,TANC2,COBL,CCDC148,MXI1,NECAB2,ARHGEF11,BACE1,SETBP1,SLC36A4,DYNC1I1,FHOD3,MTUS1,NEO1,RALGPS2,SLC30A4,MYC,ZIC5,SRGAP1,PRICKLE2,SGK1,MOXD1,NCEH1,VGLL4,GPR161,EPB41L5,B9D1,MN1,BDNF,OGDHL,SPATA13,WDR25,SHISA2,LHPP,PRDM1,PALLD,B4GALNT3,GPR137C,RERE,CTIF,GPLD1,KIAA0355,ADAMTS3,ISM1,GNAO1,MAP2K6,LRRIQ3,MYOM2,ZNF474,THAP10 |
| 3.202e-04 | -8.05 | GSE11057_NAIVE_VS_MEMORY_CD4_TCELL_UP | MSigDB lists | GSE11057_NAIVE_VS_MEMORY_CD4_TCELL_UP | 162 | 10 | 17377 | 282 |
LMLN,ZNF516,PDK1,IGIP,MPP1,BNIP3L,RHPN2,SATB1,APBA2,CENPV |
| 3.207e-04 | -8.05 | WONG_ADULT_TISSUE_STEM_MODULE | MSigDB lists | WONG_ADULT_TISSUE_STEM_MODULE | 681 | 24 | 17377 | 282 |
PHLDB2,BDNF,DUSP8,PNRC1,SLC39A8,PTPN21,CYP4V2,PLXNA2,NDRG2,RAB38,PFN2,TRIB3,FKBP9,PLK2,ZNF521,MAP7,DAB2IP,DBP,MOXD1,STXBP1,HSPA2,DDIT3,PKIA,PHC1 |
| 3.238e-04 | -8.04 | HALLMARK_HYPOXIA | MSigDB lists | HALLMARK_HYPOXIA | 193 | 11 | 17377 | 282 |
MXI1,GAPDH,PDK1,PNRC1,ALDOA,HK2,BNIP3L,EFNA3,P4HA1,PRKCA,DDIT3 |
| 3.238e-04 | -8.04 | GSE29618_BCELL_VS_MONOCYTE_DAY7_FLU_VACCINE_DN | MSigDB lists | GSE29618_BCELL_VS_MONOCYTE_DAY7_FLU_VACCINE_DN | 193 | 11 | 17377 | 282 |
ACSL1,PXN,MPP1,EMILIN2,ALDOA,KIAA0513,MAFB,SGK1,CEBPA,FAM198B,TBC1D8 |
| 3.267e-04 | -8.03 | GO_REGULATION_OF_CELLULAR_COMPONENT_BIOGENESIS | MSigDB lists | GO_REGULATION_OF_CELLULAR_COMPONENT_BIOGENESIS | 724 | 25 | 17377 | 282 |
EPB41L5,PHLDB2,BDNF,BIK,ARL2,WNT11,PRKCA,TBC1D16,TLR6,PFN2,CBLN1,FHOD3,PPM1E,PMAIP1,PLK2,DACT1,PRKCD,GTF2F2,SGK1,DAB2IP,TMOD2,STXBP1,HSPA2,COBL,TBC1D8 |
| 3.363e-04 | -8.00 | ELVIDGE_HYPOXIA_UP | MSigDB lists | ELVIDGE_HYPOXIA_UP | 163 | 10 | 17377 | 282 |
QSOX1,MXI1,PDK1,ZNF395,HK2,BNIP3L,EFNA3,P4HA1,BNIP3,PRKCA |
| 3.412e-04 | -7.98 | breast-carcinoma-basal_(triple-negative)_carcinoma | COSMIC cancer mutations | breast-carcinoma-basal_(triple-negative)_carcinoma | 3035 | 72 | 17385 | 281 |
ARHGAP26,ACVR1,RASAL2,PLXNA2,NDRG2,PRKCA,RADIL,HMCN1,TMEM53,KMO,PMAIP1,MARVELD2,ZNF521,ZDHHC23,DAB2IP,TLN2,DNAH5,TSHR,ATP6AP1L,PHLDB2,PDK1,KLHL3,PTPN6,CAPN5,ADCY1,WNT11,TNS1,ACVR2B,SGK2,SAV1,TCF7L1,RASGRF2,WWTR1,PLEKHG1,TNFSF15,MAPK13,DISP1,SCN5A,RUNX2,ARHGEF11,RASL11B,SETBP1,SATB1,FHOD3,NEO1,NUMBL,MYC,PRKCD,EHD3,RASD2,SGK1,PARP9,EPB41L5,MN1,IL17RD,PXN,SPATA13,NUAK2,MAFB,WWC1,PRDM1,PALLD,B4GALNT3,TLR6,GPLD1,GNAO1,MAP2K6,EMILIN2,KIAA0513,MYOM2,TNFRSF17,DDIT3 |
| 3.412e-04 | -7.98 | basal_(triple-negative)_carcinoma | COSMIC cancer mutations | basal_(triple-negative)_carcinoma | 3035 | 72 | 17385 | 281 |
ARHGAP26,ACVR1,RASAL2,PLXNA2,NDRG2,PRKCA,RADIL,HMCN1,TMEM53,KMO,PMAIP1,MARVELD2,ZNF521,ZDHHC23,DAB2IP,TLN2,DNAH5,TSHR,ATP6AP1L,PHLDB2,PDK1,KLHL3,PTPN6,CAPN5,ADCY1,WNT11,TNS1,ACVR2B,SGK2,SAV1,TCF7L1,RASGRF2,WWTR1,PLEKHG1,TNFSF15,MAPK13,DISP1,SCN5A,RUNX2,ARHGEF11,RASL11B,SETBP1,SATB1,FHOD3,NEO1,NUMBL,MYC,PRKCD,EHD3,RASD2,SGK1,PARP9,EPB41L5,MN1,IL17RD,PXN,SPATA13,NUAK2,MAFB,WWC1,PRDM1,PALLD,B4GALNT3,TLR6,GPLD1,GNAO1,MAP2K6,EMILIN2,KIAA0513,MYOM2,TNFRSF17,DDIT3 |
| 3.518e-04 | -7.95 | GO_CELLULAR_COMPONENT_MORPHOGENESIS | MSigDB lists | GO_CELLULAR_COMPONENT_MORPHOGENESIS | 857 | 28 | 17377 | 282 |
B9D1,EPB41L5,BDNF,MSX1,ST14,BVES,PTPN6,ADCY1,PLXNA2,EFNA3,KIF5C,STRADB,WNT11,PALLD,RADIL,FHOD3,NEO1,RERE,NUMBL,IFT81,EHD3,WWTR1,SGK1,TMOD2,DAB2IP,STXBP1,DNAH5,COBL |
| 3.535e-04 | -7.95 | GSE1432_1H_VS_24H_IFNG_MICROGLIA_UP | MSigDB lists | GSE1432_1H_VS_24H_IFNG_MICROGLIA_UP | 195 | 11 | 17377 | 282 |
RGS16,GAPDH,SCAMP1,PLK2,BNIP3L,MAPK13,PDE4D,RNF122,SATB1,NCS1,CTIF |
| 3.558e-04 | -7.94 | CREIGHTON_ENDOCRINE_THERAPY_RESISTANCE_2 | MSigDB lists | CREIGHTON_ENDOCRINE_THERAPY_RESISTANCE_2 | 368 | 16 | 17377 | 282 |
DZANK1,RASAL2,ZHX3,ABHD6,PFN2,RADIL,NIPSNAP3B,IFT81,PPM1E,IQCK,IGIP,ISM1,DNAH5,FANK1,KIAA1549,C3orf67 |
| 3.671e-04 | -7.91 | LATS2 (large tumor suppressor kinase 2) | protein interactions | 26524 | 161 | 10 | 17029 | 283 |
PHLDB2,RASAL2,WWTR1,PLEKHG1,WWC1,PLEKHA1,TANC2,SAV1,RADIL,KIAA1549 |
| 3.797e-04 | -7.88 | SCHAEFFER_PROSTATE_DEVELOPMENT_48HR_UP | MSigDB lists | SCHAEFFER_PROSTATE_DEVELOPMENT_48HR_UP | 446 | 18 | 17377 | 282 |
TMC7,SLC40A1,SLC39A8,CAPN5,PLXNA2,MAFB,RASL11B,NRN1,GAS6,GPLD1,EPCAM,RALGPS2,GPR155,SGK1,MAPK13,TMEM37,HSPA2,C3orf67 |
| 3.956e-04 | -7.84 | CACTGCC,MIR-34A,MIR-34C,MIR-449 | MSigDB lists | CACTGCC,MIR-34A,MIR-34C,MIR-449 | 264 | 13 | 17377 | 282 |
ARHGAP26,RGS17,NUMBL,ACSL1,RALGPS2,LGR4,ALDOA,ZDHHC23,SATB2,SLC2A13,NCEH1,SATB1,PKIA |
| 3.958e-04 | -7.83 | Cep152 (centrosomal protein 152) | protein interactions | 99100 | 81 | 7 | 17029 | 283 |
SPNS1,DAB2IP,PDE4D,LGR4,ALDOA,B4GALT7,MTUS1 |
| 4.048e-04 | -7.81 | CHARAFE_BREAST_CANCER_LUMINAL_VS_MESENCHYMAL_UP | MSigDB lists | CHARAFE_BREAST_CANCER_LUMINAL_VS_MESENCHYMAL_UP | 410 | 17 | 17377 | 282 |
EPB41L5,ST14,PTPN6,BLVRB,BIK,CEBPA,OVOL2,ABAT,ARRDC4,EPCAM,TRIB3,WFS1,MARVELD2,MAP7,TRIM3,DBP,RAB27B |
| 4.098e-04 | -7.80 | locomotion | biological process | GO:0040011 | 1179 | 34 | 17256 | 270 |
EPB41L5,BDNF,PXN,ACVR1,SLC9C1,DOCK1,BVES,PTPN6,EFNA3,SPATA13,PLXNA2,KIF5C,WWC1,SATB2,WNT11,TNS1,GAS6,OVOL2,COLEC10,PALLD,PRKCA,JAM3,CENPV,RERE,GPLD1,NEO1,SPNS1,EPCAM,FGR,PRKCD,DAB2IP,PDE4D,DNAH5,PARP9 |
| 4.101e-04 | -7.80 | HELLER_HDAC_TARGETS_SILENCED_BY_METHYLATION_DN | MSigDB lists | HELLER_HDAC_TARGETS_SILENCED_BY_METHYLATION_DN | 265 | 13 | 17377 | 282 |
EPCAM,TRIB3,PDK1,ST14,MYC,EHD3,SETBP1,MYOM2,MAPK13,PDE4D,TNFRSF17,TSHR,DDIT3 |
| 4.293e-04 | -7.75 | HOEBEKE_LYMPHOID_STEM_CELL_UP | MSigDB lists | HOEBEKE_LYMPHOID_STEM_CELL_UP | 84 | 7 | 17377 | 282 |
SETBP1,MN1,PALLD,DOCK1,SATB1,COBL,RERE |
| 4.385e-04 | -7.73 | myelodysplastic_syndrome | COSMIC cancer mutations | myelodysplastic_syndrome | 1191 | 35 | 17385 | 281 |
ARHGAP26,TMEM132C,ACVR1,SETBP1,CEBPA,ZNF219,PRKCA,FHOD3,PPM1E,KCTD15,MYC,RPS6KL1,PRKCD,SGK1,TSHR,FANK1,ZNF391,MN1,PDK1,NUAK2,NLGN4X,STRADB,ACVR2B,PALLD,SGK2,B4GALNT3,DYRK1B,TRIB3,FGR,MAP2K6,PLK2,ERN1,ARHGAP28,MAPK13,APBA2 |
| 4.385e-04 | -7.73 | haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-myelodysplastic_syndrome | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-myelodysplastic_syndrome | 1191 | 35 | 17385 | 281 |
ARHGAP26,TMEM132C,ACVR1,SETBP1,CEBPA,ZNF219,PRKCA,FHOD3,PPM1E,KCTD15,MYC,RPS6KL1,PRKCD,SGK1,TSHR,FANK1,ZNF391,MN1,PDK1,NUAK2,NLGN4X,STRADB,ACVR2B,PALLD,SGK2,B4GALNT3,DYRK1B,TRIB3,FGR,MAP2K6,PLK2,ERN1,ARHGAP28,MAPK13,APBA2 |
| 4.510e-04 | -7.70 | CATTGTYY_V$SOX9_B1 | MSigDB lists | CATTGTYY_V$SOX9_B1 | 339 | 15 | 17377 | 282 |
MN1,NUMBL,PNRC1,SLC39A8,GNAO1,SRGAP1,ZNF521,NDRG2,DAB2IP,PRDM1,PLEKHA1,EPHB6,COLEC10,RADIL,PHC1 |
| 4.720e-04 | -7.66 | multicellular organism development | biological process | GO:0007275 | 4836 | 101 | 17256 | 270 |
ARHGAP26,ZNF516,ACVR1,LGR4,ST14,RECK,PLXNA2,NDRG2,CEBPA,NRN1,ABAT,PRKCA,RADIL,CBLN1,NCS1,EPCAM,KCTD15,DACT1,DLX6,ZNF521,DAB2IP,MYH15,EPHB6,TSHR,DNAH5,KLHL3,SLC9C1,SOX21,PTPN6,ADCY1,NLGN4X,SATB2,WNT11,ACVR2B,PLEKHA1,SAV1,JAM3,PLEKHB1,SPATA9,DYRK1B,TCF7L1,PLK2,RBPMS2,WFS1,WWTR1,TMOD2,DISP1,DLX2,DBP,TANC2,APBA2,COBL,SCN5A,RUNX2,BVES,BIK,KIF5C,GAS6,TNFRSF10C,OVOL2,ZNF219,HERC6,SATB1,HPCAL4,MYORG,FHOD3,NEO1,KDM7A,NUMBL,MYC,ZIC5,EBF4,ACTA2,SGK1,TRIM3,BNIP3,STXBP1,BARX1,GPR161,MN1,EPB41L5,B9D1,BDNF,LZTS3,ENAM,SLC40A1,MSX1,EFNA3,MAFB,SHISA2,PRDM1,PALLD,RERE,GPLD1,GNAO1,HK2,CLMN,MYOM2,TNFRSF17,DDIT3,PHC1 |
| 4.839e-04 | -7.63 | KINSEY_TARGETS_OF_EWSR1_FLII_FUSION_DN | MSigDB lists | KINSEY_TARGETS_OF_EWSR1_FLII_FUSION_DN | 305 | 14 | 17377 | 282 |
IL17RD,ZNF827,QSOX1,FKBP9,SLC40A1,SRGAP1,SHISA2,DLX2,ABAT,DISP1,TANC2,VGLL4,SATB1,HMCN1 |
| 4.866e-04 | -7.63 | regulation of homotypic cell-cell adhesion | biological process | GO:0034110 | 24 | 4 | 17256 | 270 |
ABAT,PRKCA,UBASH3B,PRKCD |
| 4.906e-04 | -7.62 | MODULE_179 | MSigDB lists | MODULE_179 | 417 | 17 | 17377 | 282 |
ACVR1,ACSL1,SLC39A8,SOX21,WDR25,PRDM1,SAV1,CBLN1,RERE,SPNS1,ADAMTS3,MAP2K6,ALDOA,PLEKHG1,EPHB6,PDE4D,PKIA |
| 4.915e-04 | -7.62 | RIGGI_EWING_SARCOMA_PROGENITOR_DN | MSigDB lists | RIGGI_EWING_SARCOMA_PROGENITOR_DN | 171 | 10 | 17377 | 282 |
RUNX2,PDK1,ZNF395,BACE1,SRGAP1,ZNF521,MOXD1,RAB27B,TANC2,FHOD3 |
| 4.922e-04 | -7.62 | transition metal ion transmembrane transporter activity | molecular function | GO:0046915 | 41 | 5 | 17224 | 278 |
SLC40A1,SLC25A28,SLC30A4,SLC39A8,ATOX1 |
| 5.011e-04 | -7.60 | GO_POSITIVE_REGULATION_OF_MOLECULAR_FUNCTION | MSigDB lists | GO_POSITIVE_REGULATION_OF_MOLECULAR_FUNCTION | 1723 | 46 | 17377 | 282 |
ARHGAP26,RGS16,ACSL1,RASAL2,ARHGEF11,DOCK1,GAS6,PRKCA,PFN2,TIAM2,RGS17,RALGPS2,PMAIP1,DACT1,MYC,PRKCD,SRGAP1,SGK1,DAB2IP,TSHR,HSPA2,TBC1D8,EPB41L5,ADCY1,SPATA13,STRADB,WNT11,ACVR2B,SAV1,ARRDC4,SGK2,TBC1D16,TLR6,GPLD1,TRIB3,FGR,MAP2K6,PLK2,RASGRF2,WFS1,GNAO1,ERN1,PLEKHG1,ARHGAP28,TNFSF15,IQSEC2 |
| 5.022e-04 | -7.60 | large_cell | COSMIC cancer mutations | large_cell | 15281 | 264 | 17385 | 281 |
ARHGAP26,ACVR1,DUSP8,LGR4,RECK,LSM11,ALG1L,PRKCA,ABHD6,NCS1,EPDR1,PMAIP1,CFHR1,TMEM37,TSHR,TBC1D8,KLHL23,KLHL3,WISP3,EXOC6B,DSTN,BNIP3L,SLC25A28,ABCC2,TNS1,SAV1,SPATA9,PLK2,RASGRF2,ALDOA,ARHGAP28,MAPK13,TMOD2,TANC2,SCN5A,ZHX3,CYP2J2,SLC36A4,TNFRSF10C,DYNC1I1,HPCAL4,NIPSNAP3B,MTUS1,IL17D,RALGPS2,MYC,ZIC5,SRGAP1,MOXD1,STXBP1,GPR161,EPB41L5,BDNF,QSOX1,SHISA2,ARRDC4,ZNF558,ADAMTS3,ISM1,LRRIQ3,QPCTL,EMILIN2,CLMN,IQSEC2,SMYD3,ZNF516,RASAL2,ST14,FAM131C,C4A,CCDC110,PLXNA2,COLEC10,TIAM2,TMEM53,ZNF827,KMO,DACT1,DAB2IP,PJA1,PDE4D,RAB27B,DNAH5,ATP6AP1L,KIAA1549,C3orf67,DZANK1,GAPDH,PDK1,SOX21,CYB5R2,SFXN4,ADCY1,NLGN4X,SATB2,WNT11,RAB38,TBC1D16,IQCK,ZNF697,WFS1,WWTR1,PLEKHG1,TNFSF15,DBP,KLHL31,COBL,KCTD1,CCDC148,MXI1,TMEM132C,BACE1,BIK,CCNJL,KIF5C,ARL2,GAS6,ZNF219,NEO1,RGS17,GPR155,SMPDL3A,PARP9,TMC7,MN1,B9D1,SLC40A1,PXN,MPP1,GPR137C,GPLD1,TRIB3,FGR,GNAO1,MYOM2,TNFRSF17,DDIT3,B4GALT7,PHC1,CCDC126,ACSL1,HEBP1,PTPN21,NDRG2,NRN1,ABAT,ITPR2,SLC2A13,CACNB4,ABHD4,HMCN1,EPCAM,PPM1E,FKBP9,CPNE2,DLX6,TMEM143,TLN2,FANK1,ZNF391,PGBD5,PNRC1,CAPN5,TTC22,PLEKHA1,SGK2,PLEKHB1,NT5DC2,DYRK1B,SPNS1,TCF7L1,DLX2,APBA2,GPR63,LONRF1,RGS16,RUNX2,ZNF395,BVES,FBXO4,UBASH3B,CYP4V2,RASL11B,SETBP1,CHADL,SATB1,PFN2,FHOD3,SLC30A4,GAN,EBF4,BNIP3,NCEH1,VGLL4,BARX1,IL17RD,SPATA13,EFNA3,MAFB,STRADB,WWC1,WDR25,PPFIA4,LHPP,PRDM1,B4GALNT3,KIAA0355,HK2,RNF122,DOCK1,RHPN2,FAM198B,KIF21B,RADIL,CBLN1,KCTD15,RPS6KL1,EEPD1,ZDHHC23,ZNF521,MAP7,MYH15,TMEM120B,HSPA2,FAM78B,PHLDB2,UROS,PTPN6,SLC39A8,JAM3,CENPV,IFT81,LMLN,ANKRD31,RBPMS2,DISP1,NECAB2,PRSS16,ARHGEF11,BLVRB,RASD2,EHD3,PRKCD,GTF2F2,PRICKLE2,TRIM3,SGK1,CCDC122,ACTA2,KIAA0408,MSX1,NUAK2,EXOG,PALLD,TLR6,CTIF,RERE,FMO4,MAP2K6,KIAA0513,ZNF474,THAP10,RNF157,PKIA |
| 5.047e-04 | -7.59 | chr1q24 | MSigDB lists | chr1q24 | 41 | 5 | 17377 | 282 |
QSOX1,RALGPS2,FMO4,FAM78B,HMCN1 |
| 5.047e-04 | -7.59 | REACTOME_PLC_BETA_MEDIATED_EVENTS | MSigDB lists | REACTOME_PLC_BETA_MEDIATED_EVENTS | 41 | 5 | 17377 | 282 |
ITPR2,PRKCA,GNAO1,PRKCD,ADCY1 |
| 5.138e-04 | -7.57 | anatomical structure development | biological process | GO:0048856 | 5202 | 107 | 17256 | 270 |
ARHGAP26,ZNF516,ACVR1,LGR4,ST14,RECK,PLXNA2,NDRG2,CEBPA,NRN1,ABAT,COLEC10,PRKCA,RADIL,CBLN1,NCS1,EPCAM,KCTD15,DACT1,DLX6,MARVELD2,ZNF521,DAB2IP,MYH15,EPHB6,PDE4D,TSHR,DNAH5,HSPA2,KLHL3,SLC9C1,SOX21,PTPN6,ADCY1,NLGN4X,SATB2,WNT11,ACVR2B,PLEKHA1,SAV1,JAM3,PLEKHB1,SPATA9,DYRK1B,TCF7L1,PLK2,RBPMS2,WFS1,WWTR1,TMOD2,DISP1,DLX2,DBP,TANC2,APBA2,COBL,SCN5A,RUNX2,BVES,BIK,KIF5C,GAS6,TNFRSF10C,OVOL2,ZNF219,HERC6,SATB1,HPCAL4,MYORG,FHOD3,NEO1,KDM7A,NUMBL,MYC,ZIC5,EBF4,ACTA2,SGK1,TRIM3,BNIP3,STXBP1,BARX1,GPR161,MN1,EPB41L5,B9D1,BDNF,SLC40A1,LZTS3,ENAM,MSX1,EFNA3,MAFB,STRADB,SHISA2,PRDM1,PALLD,RERE,GPLD1,GNAO1,HK2,CLMN,MYOM2,TNFRSF17,SMYD3,DDIT3,PHC1 |
| 5.141e-04 | -7.57 | positive regulation of cellular metabolic process | biological process | GO:0031325 | 3074 | 70 | 17256 | 270 |
ACSL1,ZNF516,ACVR1,LGR4,CEBPA,ABAT,PRKCA,EPCAM,PMAIP1,DACT1,DAB2IP,EPHB6,TSHR,FANK1,HSPA2,SOX21,BNIP3L,ADCY1,WNT11,SATB2,PXYLP1,ACVR2B,DYRK1B,PLK2,WFS1,ERN1,WWTR1,TNFSF15,DLX2,DBP,LONRF1,NECAB2,RUNX2,BVES,ARHGEF11,FBXO4,SLX1B,OVOL2,TNFRSF10C,GAS6,ZNF219,PFN2,KDM7A,MYC,RASD2,PRKCD,EBF4,GTF2F2,INAVA,BNIP3,BARX1,GPR161,PARP9,SLC40A1,MSX1,EFNA3,WWC1,STRADB,MAFB,GAREM1,ARRDC4,TLR6,GPLD1,RERE,TRIB3,FGR,MAP2K6,HK2,SMYD3,DDIT3 |
| 5.226e-04 | -7.56 | developmental process | biological process | GO:0032502 | 5563 | 113 | 17256 | 270 |
ARHGAP26,ZNF516,ACVR1,LGR4,ST14,RECK,PLXNA2,NDRG2,CEBPA,NRN1,ABAT,COLEC10,PRKCA,RADIL,CBLN1,NCS1,EPCAM,KCTD15,DACT1,DLX6,MARVELD2,ZNF521,DAB2IP,MYH15,EPHB6,PDE4D,TSHR,TMEM120B,DNAH5,HSPA2,KLHL3,SLC9C1,SOX21,PTPN6,ADCY1,NLGN4X,SATB2,WNT11,ACVR2B,RAB38,PLEKHA1,SAV1,JAM3,PLEKHB1,SPATA9,DYRK1B,TCF7L1,PLK2,RBPMS2,WFS1,WWTR1,TMOD2,DISP1,DLX2,DBP,TANC2,APBA2,COBL,SCN5A,RUNX2,ZHX3,BVES,FBXO4,BIK,KIF5C,GAS6,TNFRSF10C,OVOL2,ZNF219,HERC6,SATB1,HPCAL4,MYORG,FHOD3,NEO1,KDM7A,NUMBL,MYC,ZIC5,PRKCD,EBF4,ACTA2,SGK1,TRIM3,BNIP3,STXBP1,BARX1,GPR161,MN1,EPB41L5,B9D1,BDNF,SLC40A1,LZTS3,ENAM,MSX1,EFNA3,MAFB,STRADB,SHISA2,PRDM1,PALLD,RERE,GPLD1,FGR,GNAO1,HK2,CLMN,MYOM2,TNFRSF17,SMYD3,DDIT3,PHC1 |
| 5.234e-04 | -7.56 | GSE4590_PRE_BCELL_VS_SMALL_PRE_BCELL_UP | MSigDB lists | GSE4590_PRE_BCELL_VS_SMALL_PRE_BCELL_UP | 142 | 9 | 17377 | 282 |
QSOX1,SLC30A4,ZHX3,RECK,HEBP1,ZDHHC23,TANC2,PFN2,NCS1 |
| 5.420e-04 | -7.52 | GO_TISSUE_DEVELOPMENT | MSigDB lists | GO_TISSUE_DEVELOPMENT | 1437 | 40 | 17377 | 282 |
ACVR1,ZNF516,RUNX2,LGR4,BVES,ST14,PLXNA2,OVOL2,SATB1,CACNB4,FHOD3,EPCAM,DLX6,MARVELD2,DACT1,MYC,ACTA2,MYH15,PDE4D,BARX1,B9D1,EPB41L5,SLC40A1,ENAM,MSX1,KLHL3,SOX21,CAPN5,WNT11,SATB2,PRDM1,ACVR2B,PALLD,SAV1,GPLD1,DYRK1B,WWTR1,DLX2,KLHL31,COBL |
| 5.432e-04 | -7.52 | PLC beta mediated events | REACTOME pathways | R-HSA-112043 | 47 | 5 | 10287 | 148 |
ITPR2,PRKCA,GNAO1,PRKCD,ADCY1 |
| 5.580e-04 | -7.49 | PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases | REACTOME pathways | R-HSA-8849471 | 27 | 4 | 10287 | 148 |
DAB2IP,PXN,RASAL2,DOCK1 |
| 5.696e-04 | -7.47 | negative regulation of platelet aggregation | biological process | GO:0090331 | 11 | 3 | 17256 | 270 |
ABAT,UBASH3B,PRKCD |
| 5.754e-04 | -7.46 | angiosarcoma | COSMIC cancer mutations | angiosarcoma | 2247 | 56 | 17385 | 281 |
ARHGAP26,CCDC148,ZNF516,LGR4,RASAL2,DOCK1,ARHGEF11,RECK,FAM131C,UBASH3B,PLXNA2,SETBP1,RHPN2,SLC36A4,ITPR2,CACNB4,DYNC1I1,RADIL,HMCN1,FHOD3,ZNF827,PPM1E,RALGPS2,SLC30A4,KMO,ZNF521,SRGAP1,MAP7,MYH15,DNAH5,TSHR,STXBP1,FANK1,C3orf67,EPB41L5,SLC39A8,CAPN5,ADCY1,SATB2,TNS1,ABCC2,PLEKHA1,PALLD,TBC1D16,TRIQK,GPR137C,RERE,GNAO1,FMO4,PLEKHG1,MYOM2,ZNF474,TANC2,APBA2,COBL,PHC1 |
| 5.754e-04 | -7.46 | soft_tissue-blood_vessel-angiosarcoma | COSMIC cancer mutations | soft_tissue-blood_vessel-angiosarcoma | 2247 | 56 | 17385 | 281 |
ARHGAP26,CCDC148,ZNF516,LGR4,RASAL2,DOCK1,ARHGEF11,RECK,FAM131C,UBASH3B,PLXNA2,SETBP1,RHPN2,SLC36A4,ITPR2,CACNB4,DYNC1I1,RADIL,HMCN1,FHOD3,ZNF827,PPM1E,RALGPS2,SLC30A4,KMO,ZNF521,SRGAP1,MAP7,MYH15,DNAH5,TSHR,STXBP1,FANK1,C3orf67,EPB41L5,SLC39A8,CAPN5,ADCY1,SATB2,TNS1,ABCC2,PLEKHA1,PALLD,TBC1D16,TRIQK,GPR137C,RERE,GNAO1,FMO4,PLEKHG1,MYOM2,ZNF474,TANC2,APBA2,COBL,PHC1 |
| 5.793e-04 | -7.45 | CCCAGAG,MIR-326 | MSigDB lists | CCCAGAG,MIR-326 | 144 | 9 | 17377 | 282 |
PPM1E,KCTD15,PXN,RALGPS2,GNAO1,PLXNA2,KIAA0513,CEBPA,PKIA |
| 5.817e-04 | -7.45 | acute_lymphoblastic_leukaemia | COSMIC cancer mutations | acute_lymphoblastic_leukaemia | 2248 | 56 | 17385 | 281 |
ACVR1,ZNF395,LGR4,PRSS16,DOCK1,ST14,PTPN21,SETBP1,ATP6V1E2,CEBPA,FAM198B,PRKCA,KIF21B,DYNC1I1,HMCN1,TIAM2,FHOD3,FKBP9,RPS6KL1,ZIC5,PRKCD,ACTA2,SGK1,DAB2IP,MYH15,TLN2,DNAH5,OR2W3,HSPA2,GPR161,EPB41L5,TMC7,PDK1,OGDHL,NUAK2,PPFIA4,STRADB,WWC1,TNS1,ABCC2,ACVR2B,SGK2,SAV1,B4GALNT3,TBC1D16,GPLD1,SPNS1,DYRK1B,TRIB3,FGR,KIAA0355,PLK2,MAP2K6,ERN1,MAPK13,COBL |
| 5.959e-04 | -7.43 | positive regulation of anion transport | biological process | GO:1903793 | 44 | 5 | 17256 | 270 |
ABAT,KMO,STXBP1,MAP2K6,PRKCD |
| 5.994e-04 | -7.42 | G-protein mediated events | REACTOME pathways | R-HSA-112040 | 48 | 5 | 10287 | 148 |
ITPR2,PRKCA,GNAO1,PRKCD,ADCY1 |
| 6.064e-04 | -7.41 | ovary-carcinoma-endometrioid_carcinoma | COSMIC cancer mutations | ovary-carcinoma-endometrioid_carcinoma | 466 | 18 | 17385 | 281 |
ACVR1,PDK1,FBXO4,NUAK2,STRADB,ACVR2B,SGK2,PRKCA,DYRK1B,TRIB3,FGR,RPS6KL1,MAP2K6,PLK2,PRKCD,ERN1,SGK1,MAPK13 |
| 6.222e-04 | -7.38 | DURAND_STROMA_S_UP | MSigDB lists | DURAND_STROMA_S_UP | 277 | 13 | 17377 | 282 |
MN1,TCF7L1,CYP2J2,SLC39A8,UBASH3B,GNAO1,RBPMS2,EHD3,PLXNA2,ARHGAP28,NDRG2,PDE4D,C3orf67 |
| 6.336e-04 | -7.36 | MARTORIATI_MDM4_TARGETS_FETAL_LIVER_UP | MSigDB lists | MARTORIATI_MDM4_TARGETS_FETAL_LIVER_UP | 209 | 11 | 17377 | 282 |
CPNE2,PDK1,PMAIP1,ST14,HK2,BNIP3L,TMEM143,P4HA1,BNIP3,NRN1,ABHD4 |
| 6.351e-04 | -7.36 | oesophagus-carcinoma-adenocarcinoma | COSMIC cancer mutations | oesophagus-carcinoma-adenocarcinoma | 13493 | 240 | 17385 | 281 |
ARHGAP26,CCDC126,ACSL1,ACVR1,DUSP8,LGR4,RECK,HEBP1,LSM11,PTPN21,ALG1L,NDRG2,NRN1,SLC2A13,ITPR2,ABAT,PRKCA,ABHD4,CACNB4,ABHD6,HMCN1,NCS1,EPDR1,EPCAM,CPNE2,FKBP9,PPM1E,PMAIP1,DLX6,MARVELD2,CFHR1,TMEM143,TLN2,OR2W3,TSHR,FANK1,TBC1D8,PGBD5,KLHL23,KLHL3,WISP3,EXOC6B,DSTN,CAPN5,TTC22,ABCC2,TNS1,PLEKHA1,ACVR2B,SGK2,SAV1,NT5DC2,PLEKHB1,SPNS1,DYRK1B,SPATA9,TCF7L1,PLK2,RASGRF2,ERN1,ALDOA,ARHGAP28,MAPK13,TMOD2,DLX2,TANC2,APBA2,LONRF1,GPR63,SCN5A,TMEM63C,ZNF395,ZHX3,BVES,UBASH3B,CYP2J2,CYP4V2,SETBP1,ATP6V1E2,CHADL,SLC36A4,TNFRSF10C,SATB1,DYNC1I1,HPCAL4,NIPSNAP3B,FHOD3,MTUS1,IL17D,NUMBL,RALGPS2,SLC30A4,MYC,EBF4,SRGAP1,GAN,BNIP3,NCEH1,MOXD1,VGLL4,STXBP1,GPR161,EPB41L5,BDNF,IL17RD,QSOX1,EFNA3,PPFIA4,WDR25,WWC1,STRADB,SHISA2,PRDM1,LHPP,ARRDC4,B4GALNT3,ZNF558,KIAA0355,ADAMTS3,ISM1,LRRIQ3,QPCTL,EMILIN2,HK2,CLMN,IQSEC2,RNF122,ZNF516,RASAL2,DOCK1,ST14,C4A,FAM131C,CCDC110,PLXNA2,RHPN2,FAM198B,COLEC10,KIF21B,RADIL,CBLN1,TIAM2,TMEM53,ZNF827,KCTD15,KMO,RPS6KL1,DACT1,ZNF521,ZDHHC23,EEPD1,MAP7,DAB2IP,MYH15,PJA1,PDE4D,DNAH5,TMEM120B,FAM78B,ATP6AP1L,HSPA2,C3orf67,DZANK1,PHLDB2,UROS,PDK1,SLC39A8,PTPN6,CYB5R2,SFXN4,ADCY1,NLGN4X,SATB2,WNT11,RAB38,TBC1D16,TRIQK,JAM3,IQCK,LMLN,WFS1,RBPMS2,WWTR1,PLEKHG1,P4HA1,TNFSF15,DISP1,DBP,KLHL31,COBL,CCDC148,MXI1,TMEM132C,NECAB2,PRSS16,ARHGEF11,BACE1,BIK,BLVRB,CCNJL,OVOL2,ZNF219,NEO1,RGS17,GPR155,PRKCD,EHD3,GTF2F2,ACTA2,CCDC122,TRIM3,PRICKLE2,SGK1,KIAA0408,SMPDL3A,PARP9,TMC7,MN1,B9D1,SLC40A1,MSX1,MPP1,OGDHL,NUAK2,PALLD,TLR6,GPR137C,RERE,GPLD1,CTIF,TRIB3,FGR,MAP2K6,GNAO1,FMO4,KIAA0513,MYOM2,RNF157,PKIA,PHC1 |
| 6.388e-04 | -7.36 | kidney-Wilms_tumour | COSMIC cancer mutations | kidney-Wilms_tumour | 549 | 20 | 17385 | 281 |
ACVR1,PDK1,NUAK2,STRADB,LHPP,ACVR2B,SGK2,PRKCA,RERE,DYRK1B,TRIB3,FGR,PLK2,RPS6KL1,RASGRF2,MAP2K6,PRKCD,ERN1,SGK1,MAPK13 |
| 6.412e-04 | -7.35 | DAVICIONI_TARGETS_OF_PAX_FOXO1_FUSIONS_DN | MSigDB lists | DAVICIONI_TARGETS_OF_PAX_FOXO1_FUSIONS_DN | 65 | 6 | 17377 | 282 |
PDE4D,MOXD1,COBL,PLK2,PKIA,TBC1D8 |
| 6.494e-04 | -7.34 | GTPase regulator activity | molecular function | GO:0030695 | 316 | 14 | 17224 | 278 |
ARHGAP26,RGS16,RGS17,RASAL2,ARHGEF11,DOCK1,SRGAP1,ARL2,ARHGAP28,DAB2IP,WNT11,TBC1D16,TIAM2,TBC1D8 |
| 6.534e-04 | -7.33 | Wilms_tumour | COSMIC cancer mutations | Wilms_tumour | 550 | 20 | 17385 | 281 |
ACVR1,PDK1,NUAK2,STRADB,LHPP,ACVR2B,SGK2,PRKCA,RERE,DYRK1B,TRIB3,FGR,PLK2,RPS6KL1,RASGRF2,MAP2K6,PRKCD,ERN1,SGK1,MAPK13 |
| 6.563e-04 | -7.33 | bile_duct | COSMIC cancer mutations | bile_duct | 15555 | 267 | 17385 | 281 |
ARHGAP26,ACVR1,DUSP8,LGR4,RECK,LSM11,ALG1L,CEBPA,PRKCA,ABHD6,NCS1,EPDR1,PMAIP1,CFHR1,TMEM37,TSHR,KLHL23,KLHL3,WISP3,EXOC6B,DSTN,BNIP3L,SLC25A28,ABCC2,TNS1,ACVR2B,SAV1,SPATA9,PLK2,RASGRF2,ALDOA,ARHGAP28,MAPK13,TMOD2,TANC2,SCN5A,ZHX3,CYP2J2,SLC36A4,TNFRSF10C,DYNC1I1,HPCAL4,NIPSNAP3B,MTUS1,IL17D,RALGPS2,MYC,ZIC5,SRGAP1,MOXD1,STXBP1,GPR161,EPB41L5,BDNF,QSOX1,SHISA2,ARRDC4,OR11H4,ZNF558,ADAMTS3,ISM1,LRRIQ3,QPCTL,EMILIN2,CLMN,IQSEC2,SMYD3,ZNF516,RASAL2,ST14,FAM131C,CCDC110,PLXNA2,COLEC10,TIAM2,TMEM53,KMO,DACT1,DAB2IP,PJA1,PDE4D,RAB27B,DNAH5,ATP6AP1L,KIAA1549,C3orf67,GAPDH,PDK1,SOX21,CYB5R2,SFXN4,ADCY1,NLGN4X,SATB2,WNT11,RAB38,TBC1D16,IQCK,WFS1,WWTR1,PLEKHG1,P4HA1,TNFSF15,DBP,COBL,KCTD1,C2orf88,CCDC148,MXI1,TMEM132C,BACE1,BIK,CCNJL,KIF5C,GAS6,ZNF219,NEO1,RGS17,GPR155,SMPDL3A,PARP9,TMC7,MN1,B9D1,SLC40A1,PXN,MPP1,GPR137C,GPLD1,TRIB3,FGR,GNAO1,MYOM2,TNFRSF17,DDIT3,B4GALT7,PHC1,CCDC126,ACSL1,HEBP1,PTPN21,NDRG2,NRN1,ABAT,ITPR2,SLC2A13,ABHD4,HMCN1,EPCAM,PPM1E,FKBP9,CPNE2,DLX6,TMEM143,TLN2,FANK1,OR2W3,ZNF391,PGBD5,PNRC1,CAPN5,TTC22,PLEKHA1,SGK2,NT5DC2,PLEKHB1,DYRK1B,SPNS1,TCF7L1,ERN1,DLX2,APBA2,GPR63,LONRF1,RGS16,RUNX2,ZNF395,BVES,FBXO4,UBASH3B,CYP4V2,ATP6V1E2,RASL11B,SETBP1,CHADL,SATB1,PFN2,FHOD3,NUMBL,SLC30A4,GAN,EBF4,BNIP3,NCEH1,VGLL4,BARX1,IL17RD,SPATA13,EFNA3,MAFB,STRADB,WWC1,WDR25,PPFIA4,LHPP,PRDM1,B4GALNT3,KIAA0355,HK2,RNF122,DOCK1,RHPN2,FAM198B,KIF21B,RADIL,CBLN1,KCTD15,RPS6KL1,ZDHHC23,EEPD1,ZNF521,MAP7,MYH15,TMEM120B,HSPA2,FAM78B,PHLDB2,UROS,PTPN6,SLC39A8,JAM3,CENPV,IFT81,LMLN,ANKRD31,RBPMS2,DISP1,NECAB2,PRSS16,ARHGEF11,BLVRB,OVOL2,RASD2,EHD3,PRKCD,GTF2F2,ACTA2,PRICKLE2,TRIM3,SGK1,CCDC122,KIAA0408,MSX1,NUAK2,OGDHL,EXOG,PALLD,TLR6,CTIF,RERE,FMO4,MAP2K6,KIAA0513,ZNF474,THAP10,RNF157,PKIA |
| 6.563e-04 | -7.33 | biliary_tract-bile_duct-carcinoma-adenocarcinoma | COSMIC cancer mutations | biliary_tract-bile_duct-carcinoma-adenocarcinoma | 15555 | 267 | 17385 | 281 |
ARHGAP26,ACVR1,DUSP8,LGR4,RECK,LSM11,ALG1L,CEBPA,PRKCA,ABHD6,NCS1,EPDR1,PMAIP1,CFHR1,TMEM37,TSHR,KLHL23,KLHL3,WISP3,EXOC6B,DSTN,BNIP3L,SLC25A28,ABCC2,TNS1,ACVR2B,SAV1,SPATA9,PLK2,RASGRF2,ALDOA,ARHGAP28,MAPK13,TMOD2,TANC2,SCN5A,ZHX3,CYP2J2,SLC36A4,TNFRSF10C,DYNC1I1,HPCAL4,NIPSNAP3B,MTUS1,IL17D,RALGPS2,MYC,ZIC5,SRGAP1,MOXD1,STXBP1,GPR161,EPB41L5,BDNF,QSOX1,SHISA2,ARRDC4,OR11H4,ZNF558,ADAMTS3,ISM1,LRRIQ3,QPCTL,EMILIN2,CLMN,IQSEC2,SMYD3,ZNF516,RASAL2,ST14,FAM131C,CCDC110,PLXNA2,COLEC10,TIAM2,TMEM53,KMO,DACT1,DAB2IP,PJA1,PDE4D,RAB27B,DNAH5,ATP6AP1L,KIAA1549,C3orf67,GAPDH,PDK1,SOX21,CYB5R2,SFXN4,ADCY1,NLGN4X,SATB2,WNT11,RAB38,TBC1D16,IQCK,WFS1,WWTR1,PLEKHG1,P4HA1,TNFSF15,DBP,COBL,KCTD1,C2orf88,CCDC148,MXI1,TMEM132C,BACE1,BIK,CCNJL,KIF5C,GAS6,ZNF219,NEO1,RGS17,GPR155,SMPDL3A,PARP9,TMC7,MN1,B9D1,SLC40A1,PXN,MPP1,GPR137C,GPLD1,TRIB3,FGR,GNAO1,MYOM2,TNFRSF17,DDIT3,B4GALT7,PHC1,CCDC126,ACSL1,HEBP1,PTPN21,NDRG2,NRN1,ABAT,ITPR2,SLC2A13,ABHD4,HMCN1,EPCAM,PPM1E,FKBP9,CPNE2,DLX6,TMEM143,TLN2,FANK1,OR2W3,ZNF391,PGBD5,PNRC1,CAPN5,TTC22,PLEKHA1,SGK2,NT5DC2,PLEKHB1,DYRK1B,SPNS1,TCF7L1,ERN1,DLX2,APBA2,GPR63,LONRF1,RGS16,RUNX2,ZNF395,BVES,FBXO4,UBASH3B,CYP4V2,ATP6V1E2,RASL11B,SETBP1,CHADL,SATB1,PFN2,FHOD3,NUMBL,SLC30A4,GAN,EBF4,BNIP3,NCEH1,VGLL4,BARX1,IL17RD,SPATA13,EFNA3,MAFB,STRADB,WWC1,WDR25,PPFIA4,LHPP,PRDM1,B4GALNT3,KIAA0355,HK2,RNF122,DOCK1,RHPN2,FAM198B,KIF21B,RADIL,CBLN1,KCTD15,RPS6KL1,ZDHHC23,EEPD1,ZNF521,MAP7,MYH15,TMEM120B,HSPA2,FAM78B,PHLDB2,UROS,PTPN6,SLC39A8,JAM3,CENPV,IFT81,LMLN,ANKRD31,RBPMS2,DISP1,NECAB2,PRSS16,ARHGEF11,BLVRB,OVOL2,RASD2,EHD3,PRKCD,GTF2F2,ACTA2,PRICKLE2,TRIM3,SGK1,CCDC122,KIAA0408,MSX1,NUAK2,OGDHL,EXOG,PALLD,TLR6,CTIF,RERE,FMO4,MAP2K6,KIAA0513,ZNF474,THAP10,RNF157,PKIA |
| 6.564e-04 | -7.33 | GNF2_AF1Q | MSigDB lists | GNF2_AF1Q | 25 | 4 | 17377 | 282 |
KIF5C,DYNC1I1,GNAO1,ADCY1 |
| 6.717e-04 | -7.31 | BCL2 (BCL2, apoptosis regulator) | protein interactions | 596 | 115 | 8 | 17029 | 283 |
SPNS1,BNIP3,PXN,PRKCA,PMAIP1,MYC,BIK,BNIP3L |
| 6.723e-04 | -7.30 | GSE40666_WT_VS_STAT1_KO_CD8_TCELL_WITH_IFNA_STIM_90MIN_UP | MSigDB lists | GSE40666_WT_VS_STAT1_KO_CD8_TCELL_WITH_IFNA_STIM_90MIN_UP | 178 | 10 | 17377 | 282 |
ARHGAP26,SLC40A1,DSTN,EHD3,BIK,SGK1,PRDM1,ARRDC4,TIAM2,SMPDL3A |
| 6.744e-04 | -7.30 | nicotinamide nucleotide biosynthetic process | biological process | GO:0019359 | 68 | 6 | 17256 | 270 |
GAPDH,KMO,ALDOA,PARP9,OGDHL,HK2 |
| 6.744e-04 | -7.30 | pyridine nucleotide biosynthetic process | biological process | GO:0019363 | 68 | 6 | 17256 | 270 |
GAPDH,KMO,ALDOA,PARP9,OGDHL,HK2 |
| 6.958e-04 | -7.27 | ACAACTT,MIR-382 | MSigDB lists | ACAACTT,MIR-382 | 66 | 6 | 17377 | 282 |
SGK1,NDRG2,BDNF,ACVR1,HSPA2,MTUS1 |
| 6.968e-04 | -7.27 | chromophobe_renal_cell_carcinoma | COSMIC cancer mutations | chromophobe_renal_cell_carcinoma | 432 | 17 | 17385 | 281 |
ACVR1,PDK1,NUAK2,STRADB,ACVR2B,SGK2,PRKCA,DYRK1B,TRIB3,FGR,RPS6KL1,MAP2K6,PLK2,ERN1,PRKCD,SGK1,MAPK13 |
| 6.968e-04 | -7.27 | kidney-carcinoma-chromophobe_renal_cell_carcinoma | COSMIC cancer mutations | kidney-carcinoma-chromophobe_renal_cell_carcinoma | 432 | 17 | 17385 | 281 |
ACVR1,PDK1,NUAK2,STRADB,ACVR2B,SGK2,PRKCA,DYRK1B,TRIB3,FGR,RPS6KL1,MAP2K6,PLK2,ERN1,PRKCD,SGK1,MAPK13 |
| 6.986e-04 | -7.27 | AIP1-IRE1 complex | cellular component | GO:1990597 | 3 | 2 | 18223 | 280 |
DAB2IP,ERN1 |
| 7.021e-04 | -7.26 | GSE37605_FOXP3_FUSION_GFP_VS_IRES_GFP_TREG_C57BL6_UP | MSigDB lists | GSE37605_FOXP3_FUSION_GFP_VS_IRES_GFP_TREG_C57BL6_UP | 179 | 10 | 17377 | 282 |
FKBP9,PLK2,MYC,NUAK2,SGK1,NDRG2,RASL11B,TNS1,PDE4D,PJA1 |
| 7.058e-04 | -7.26 | GSE21063_CTRL_VS_ANTI_IGM_STIM_BCELL_8H_UP | MSigDB lists | GSE21063_CTRL_VS_ANTI_IGM_STIM_BCELL_8H_UP | 148 | 9 | 17377 | 282 |
EPCAM,ENAM,LMLN,KMO,PLK2,PTPN21,ERN1,RNF122,B4GALNT3 |
| 7.063e-04 | -7.26 | blood_vessel | COSMIC cancer mutations | blood_vessel | 2266 | 56 | 17385 | 281 |
ARHGAP26,CCDC148,ZNF516,LGR4,RASAL2,DOCK1,ARHGEF11,RECK,FAM131C,UBASH3B,PLXNA2,SETBP1,RHPN2,SLC36A4,ITPR2,CACNB4,DYNC1I1,RADIL,HMCN1,FHOD3,ZNF827,PPM1E,RALGPS2,SLC30A4,KMO,ZNF521,SRGAP1,MAP7,MYH15,DNAH5,TSHR,STXBP1,FANK1,C3orf67,EPB41L5,SLC39A8,CAPN5,ADCY1,SATB2,TNS1,ABCC2,PLEKHA1,PALLD,TBC1D16,TRIQK,GPR137C,RERE,GNAO1,FMO4,PLEKHG1,MYOM2,ZNF474,TANC2,APBA2,COBL,PHC1 |
| 7.155e-04 | -7.24 | MODULE_11 | MSigDB lists | MODULE_11 | 511 | 19 | 17377 | 282 |
ACSL1,DUSP8,PLXNA2,SETBP1,KIF5C,ABAT,KIF21B,DYNC1I1,CBLN1,PLEKHB1,NEO1,MTUS1,GNAO1,MAP7,SGK1,DBP,APBA2,HSPA2,PKIA |
| 7.172e-04 | -7.24 | SDC4 (syndecan 4) | protein interactions | 6385 | 25 | 4 | 17029 | 283 |
PXN,PRKCA,MYC,PRKCD |
| 7.242e-04 | -7.23 | positive regulation of glutamate secretion, neurotransmission | biological process | GO:1903296 | 3 | 2 | 17256 | 270 |
KMO,STXBP1 |
| 7.242e-04 | -7.23 | cellular response to sorbitol | biological process | GO:0072709 | 3 | 2 | 17256 | 270 |
MAPK13,MAP2K6 |
| 7.242e-04 | -7.23 | regulation of glutamate secretion, neurotransmission | biological process | GO:1903294 | 3 | 2 | 17256 | 270 |
KMO,STXBP1 |
| 7.329e-04 | -7.22 | V$HFH3_01 | MSigDB lists | V$HFH3_01 | 180 | 10 | 17377 | 282 |
KCTD15,RUNX2,SCAMP1,SLC39A8,GNAO1,SGK1,TNFSF15,CEBPA,PRDM1,COLEC10 |
| 7.388e-04 | -7.21 | GO_POSITIVE_REGULATION_OF_CATALYTIC_ACTIVITY | MSigDB lists | GO_POSITIVE_REGULATION_OF_CATALYTIC_ACTIVITY | 1460 | 40 | 17377 | 282 |
ARHGAP26,RGS16,ACSL1,RASAL2,ARHGEF11,DOCK1,GAS6,PRKCA,PFN2,TIAM2,RGS17,RALGPS2,PMAIP1,MYC,PRKCD,SRGAP1,DAB2IP,TSHR,HSPA2,TBC1D8,ADCY1,SPATA13,STRADB,WNT11,ACVR2B,ARRDC4,TBC1D16,TLR6,GPLD1,TRIB3,FGR,MAP2K6,WFS1,GNAO1,RASGRF2,ERN1,PLEKHG1,ARHGAP28,TNFSF15,IQSEC2 |
| 7.469e-04 | -7.20 | DUF3498 | pfam domains | PF12004 | 3 | 2 | 17054 | 271 |
DAB2IP,RASAL2 |
| 7.473e-04 | -7.20 | regulation of localization | biological process | GO:0032879 | 2674 | 62 | 17256 | 270 |
SCN5A,ACVR1,NECAB2,LGR4,DOCK1,BVES,RECK,C4A,FBXO4,UBASH3B,PLXNA2,ARL2,ITPR2,GAS6,ABAT,PRKCA,CACNB4,PFN2,ABHD6,NCS1,MTUS1,SLC30A4,PMAIP1,KMO,PRKCD,EHD3,SRGAP1,SGK1,DAB2IP,PDE4D,TMEM37,RAB27B,STXBP1,HSPA2,PARP9,TBC1D8,EPB41L5,B9D1,PHLDB2,BDNF,GAPDH,MPP1,PTPN6,BNIP3L,SPATA13,WWC1,WNT11,SGK2,TBC1D16,TLR6,JAM3,GPLD1,TRIB3,FGR,PLK2,MAP2K6,GNAO1,WFS1,HK2,DISP1,DDIT3,PKIA |
| 7.519e-04 | -7.19 | MODULE_212 | MSigDB lists | MODULE_212 | 319 | 14 | 17377 | 282 |
MXI1,ACSL1,PNRC1,FMO4,CYP2J2,MAP2K6,MPP1,BLVRB,ALDOA,MAP7,STRADB,BNIP3,TNS1,MTUS1 |
| 7.580e-04 | -7.18 | DUF3498 | interpro domains | IPR021887 | 3 | 2 | 18492 | 296 |
DAB2IP,RASAL2 |
| 7.649e-04 | -7.18 | GSE45739_UNSTIM_VS_ACD3_ACD28_STIM_NRAS_KO_CD4_TCELL_UP | MSigDB lists | GSE45739_UNSTIM_VS_ACD3_ACD28_STIM_NRAS_KO_CD4_TCELL_UP | 181 | 10 | 17377 | 282 |
ACVR1,PDK1,ARHGEF11,KIAA0355,KLHL3,EPHB6,DBP,PRKCA,RERE,PHC1 |
| 7.649e-04 | -7.18 | GSE45739_UNSTIM_VS_ACD3_ACD28_STIM_WT_CD4_TCELL_UP | MSigDB lists | GSE45739_UNSTIM_VS_ACD3_ACD28_STIM_WT_CD4_TCELL_UP | 181 | 10 | 17377 | 282 |
ACVR1,ARHGEF11,DACT1,NDRG2,SLC25A28,ACVR2B,EPHB6,GAS6,PFN2,RERE |
| 7.659e-04 | -7.17 | BRACHAT_RESPONSE_TO_METHOTREXATE_DN | MSigDB lists | BRACHAT_RESPONSE_TO_METHOTREXATE_DN | 26 | 4 | 17377 | 282 |
GAPDH,EMILIN2,ALDOA,BNIP3L |
| 7.659e-04 | -7.17 | GNF2_TM4SF2 | MSigDB lists | GNF2_TM4SF2 | 26 | 4 | 17377 | 282 |
STXBP1,GNAO1,HPCAL4,PGBD5 |
| 7.665e-04 | -7.17 | RTAAACA_V$FREAC2_01 | MSigDB lists | RTAAACA_V$FREAC2_01 | 856 | 27 | 17377 | 282 |
GPR63,LONRF1,MN1,BDNF,ACSL1,PNRC1,SCAMP1,BIK,PLXNA2,NDRG2,SLC25A28,SATB2,PRDM1,COLEC10,ZNF219,DYNC1I1,HMCN1,NEO1,KCTD15,RALGPS2,MAP2K6,GNAO1,MYC,ZNF521,DAB2IP,PJA1,PKIA |
| 7.691e-04 | -7.17 | TTGTTT_V$FOXO4_01 | MSigDB lists | TTGTTT_V$FOXO4_01 | 1908 | 49 | 17377 | 282 |
GPR63,MXI1,ACVR1,RUNX2,DUSP8,ZNF395,PTPN21,BIK,PLXNA2,ZNF219,SATB1,CBLN1,HMCN1,NEO1,RALGPS2,DACT1,ZIC5,GTF2F2,ZNF521,MAP7,SGK1,EPHB6,PDE4D,TLN2,TSHR,VGLL4,HSPA2,DZANK1,ENAM,BDNF,SLC40A1,MSX1,PNRC1,KLHL3,SFXN4,SOX21,WDR25,SLC25A28,SATB2,PRDM1,PALLD,GPLD1,GNAO1,MAP2K6,DLX2,DBP,APBA2,RNF122,PKIA |
| 7.829e-04 | -7.15 | GO_INTRACELLULAR_SIGNAL_TRANSDUCTION | MSigDB lists | GO_INTRACELLULAR_SIGNAL_TRANSDUCTION | 1513 | 41 | 17377 | 282 |
RASAL2,ARHGEF11,DOCK1,ARL2,RASL11B,ITPR2,GAS6,PRKCA,NCS1,TIAM2,RALGPS2,PMAIP1,GPR155,MYC,RASD2,PRKCD,SGK1,BNIP3,DAB2IP,PDE4D,RAB27B,IL17RD,PDK1,PTPN6,NUAK2,ADCY1,WWC1,RAB38,PLEKHA1,SAV1,SGK2,TLR6,TRIB3,RASGRF2,PLK2,MAP2K6,WWTR1,ERN1,TNFSF15,MAPK13,DDIT3 |
| 7.850e-04 | -7.15 | bZIP_2 | pfam domains | PF07716 | 12 | 3 | 17054 | 271 |
CEBPA,DBP,DDIT3 |
| 7.900e-04 | -7.14 | Prot_kinase_dom | interpro domains | IPR000719 | 481 | 18 | 18492 | 296 |
ACVR1,NUAK2,STRADB,ACVR2B,SGK2,PRKCA,GRK3,DYRK1B,TRIB3,FGR,MAP2K6,PLK2,RPS6KL1,PRKCD,ERN1,SGK1,MAPK13,EPHB6 |
| 7.939e-04 | -7.14 | V$ER_Q6_01 | MSigDB lists | V$ER_Q6_01 | 249 | 12 | 17377 | 282 |
PPM1E,PXN,MAP2K6,ALDOA,ERN1,BNIP3L,NDRG2,WWC1,WNT11,PRDM1,OVOL2,SATB1 |
| 7.981e-04 | -7.13 | GSE3982_MAST_CELL_VS_NKCELL_UP | MSigDB lists | GSE3982_MAST_CELL_VS_NKCELL_UP | 182 | 10 | 17377 | 282 |
FKBP9,ACVR1,ZNF516,ADAMTS3,NDRG2,ABHD6,STXBP1,HSPA2,SMYD3,TBC1D8 |
| 7.981e-04 | -7.13 | GSE3982_BCELL_VS_CENT_MEMORY_CD4_TCELL_DN | MSigDB lists | GSE3982_BCELL_VS_CENT_MEMORY_CD4_TCELL_DN | 182 | 10 | 17377 | 282 |
PXN,RASAL2,KLHL3,KLHL23,DLX6,EXOC6B,TTC22,TNS1,KIF21B,SATB1 |
| 7.981e-04 | -7.13 | GSE7400_CTRL_VS_CSF3_IN_VIVO_TREATED_PBMC_UP | MSigDB lists | GSE7400_CTRL_VS_CSF3_IN_VIVO_TREATED_PBMC_UP | 182 | 10 | 17377 | 282 |
KIAA0355,FBXO4,RASGRF2,MYC,EHD3,BNIP3,TTC22,PJA1,RAB27B,PKIA |
| 7.981e-04 | -7.13 | GSE30971_WBP7_HET_VS_KO_MACROPHAGE_2H_LPS_STIM_UP | MSigDB lists | GSE30971_WBP7_HET_VS_KO_MACROPHAGE_2H_LPS_STIM_UP | 182 | 10 | 17377 | 282 |
ARHGAP26,GAPDH,RASAL2,MPP1,UBASH3B,KIAA0513,PJA1,DISP1,NCEH1,ABHD6 |
| 8.068e-04 | -7.12 | Inflammatory mediator regulation of TRP channels | KEGG pathways | ko04750 | 97 | 7 | 7161 | 113 |
MAPK13,ITPR2,PRKCA,MAP2K6,CYP2J2,PRKCD,ADCY1 |
| 8.068e-04 | -7.12 | Inflammatory mediator regulation of TRP channels | KEGG pathways | hsa04750 | 97 | 7 | 7161 | 113 |
MAPK13,ITPR2,PRKCA,MAP2K6,CYP2J2,PRKCD,ADCY1 |
| 8.162e-04 | -7.11 | positive regulation of hydrolase activity | biological process | GO:0051345 | 755 | 24 | 17256 | 270 |
ARHGAP26,RGS16,RASAL2,ARHGEF11,DOCK1,EFNA3,WNT11,DYNC1I1,PFN2,TBC1D16,TIAM2,GPLD1,RGS17,PMAIP1,GNAO1,MYC,PRKCD,ERN1,SRGAP1,ARHGAP28,TNFSF15,DAB2IP,HSPA2,TBC1D8 |
| 8.166e-04 | -7.11 | XDH (xanthine dehydrogenase) | protein interactions | 7498 | 3 | 2 | 17029 | 283 |
CCDC110,MYC |
| 8.208e-04 | -7.11 | GTPase activator activity | molecular function | GO:0005096 | 287 | 13 | 17224 | 278 |
ARHGAP26,RGS16,RGS17,RASAL2,ARHGEF11,DOCK1,SRGAP1,ARHGAP28,DAB2IP,WNT11,TBC1D16,TIAM2,TBC1D8 |
| 8.223e-04 | -7.10 | regulation of molecular function | biological process | GO:0065009 | 3181 | 71 | 17256 | 270 |
ARHGAP26,ACSL1,DUSP8,RASAL2,DOCK1,RECK,C4A,PLXNA2,CEBPA,CACNB4,TIAM2,PPM1E,PMAIP1,DACT1,CFHR1,DAB2IP,PDE4D,EPHB6,TSHR,FANK1,HSPA2,TBC1D8,GAPDH,WISP3,PTPN6,ADCY1,WNT11,ACVR2B,SGK2,SAV1,TBC1D16,PLK2,WFS1,ERN1,WWTR1,ARHGAP28,TNFSF15,RGS16,MXI1,BVES,ARHGEF11,UBASH3B,ARL2,TNFRSF10C,GAS6,PFN2,DYNC1I1,IL17D,RGS17,MYC,PRKCD,EHD3,SRGAP1,SGK1,INAVA,PARP9,EPB41L5,BDNF,MSX1,EFNA3,STRADB,ARRDC4,TLR6,GPLD1,TRIB3,FGR,GNAO1,MAP2K6,SMYD3,PKIA,DDIT3 |
| 8.324e-04 | -7.09 | RAF_UP.V1_DN | MSigDB lists | RAF_UP.V1_DN | 183 | 10 | 17377 | 282 |
PPM1E,MXI1,PMAIP1,SLC39A8,PLK2,MAFB,SATB2,ABAT,PALLD,TBC1D16 |
| 8.366e-04 | -7.09 | CEBPG (CCAAT enhancer binding protein gamma) | protein interactions | 1054 | 26 | 4 | 17029 | 283 |
CEBPA,DBP,DDIT3,GTF2F2 |
| 8.541e-04 | -7.07 | KIM_WT1_TARGETS_12HR_UP | MSigDB lists | KIM_WT1_TARGETS_12HR_UP | 152 | 9 | 17377 | 282 |
MN1,MSX1,ACSL1,ZNF395,LGR4,P4HA1,ABAT,TLN2,MTUS1 |
| 8.541e-04 | -7.07 | GSE17974_IL4_AND_ANTI_IL12_VS_UNTREATED_24H_ACT_CD4_TCELL_UP | MSigDB lists | GSE17974_IL4_AND_ANTI_IL12_VS_UNTREATED_24H_ACT_CD4_TCELL_UP | 152 | 9 | 17377 | 282 |
EPB41L5,SLC40A1,CCDC122,STRADB,SGK1,RAB27B,TNFRSF17,ABHD6,PKIA |
| 8.605e-04 | -7.06 | MODULE_100 | MSigDB lists | MODULE_100 | 519 | 19 | 17377 | 282 |
ACSL1,DUSP8,PLXNA2,SETBP1,KIF5C,ABAT,KIF21B,DYNC1I1,CBLN1,PLEKHB1,NEO1,MTUS1,GNAO1,MAP7,DBP,APBA2,STXBP1,HSPA2,PKIA |
| 8.635e-04 | -7.05 | haematopoietic_and_lymphoid_tissue-soft_tissue-lymphoid_neoplasm-diffuse_large_B_cell_lymphoma | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-soft_tissue-lymphoid_neoplasm-diffuse_large_B_cell_lymphoma | 69 | 6 | 17385 | 281 |
SGK1,NLGN4X,SLC30A4,DNAH5,MYC,ZIC5 |
| 8.642e-04 | -7.05 | BIOCARTA_KERATINOCYTE_PATHWAY | MSigDB lists | BIOCARTA_KERATINOCYTE_PATHWAY | 46 | 5 | 17377 | 282 |
MAPK13,CEBPA,PRKCA,MAP2K6,PRKCD |
| 8.757e-04 | -7.04 | negative regulation of cell communication | biological process | GO:0010648 | 1379 | 37 | 17256 | 270 |
RGS16,RUNX2,ACVR1,DUSP8,LGR4,RASAL2,UBASH3B,RASL11B,NDRG2,GAS6,ABHD6,CBLN1,RGS17,DACT1,MYC,PRKCD,DAB2IP,EPHB6,STXBP1,BARX1,GPR161,PTPN6,WWC1,STRADB,NLGN4X,SHISA2,WNT11,PRDM1,PLEKHA1,TLR6,TRIB3,RBPMS2,WFS1,PLK2,WWTR1,DLX2,DDIT3 |
| 8.817e-04 | -7.03 | ENGELMANN_CANCER_PROGENITORS_DN | MSigDB lists | ENGELMANN_CANCER_PROGENITORS_DN | 69 | 6 | 17377 | 282 |
SGK1,MAFB,SLX1B,CEBPA,HSPA2,ADCY1 |
| 8.877e-04 | -7.03 | GO_NEGATIVE_REGULATION_OF_FIBROBLAST_PROLIFERATION | MSigDB lists | GO_NEGATIVE_REGULATION_OF_FIBROBLAST_PROLIFERATION | 27 | 4 | 17377 | 282 |
DAB2IP,PMAIP1,MYC,B4GALT7 |
| 8.940e-04 | -7.02 | DNAJB12 (DnaJ heat shock protein family (Hsp40) member B12) | protein interactions | 54788 | 12 | 3 | 17029 | 283 |
HSPA2,DSTN,MYC |
| 8.972e-04 | -7.02 | PH_DOMAIN | prosite domains | PS50003 | 246 | 12 | 12060 | 202 |
ARHGAP26,PHLDB2,RALGPS2,ARHGEF11,RASGRF2,SPATA13,PLEKHG1,DAB2IP,PLEKHA1,GRK3,PLEKHB1,TIAM2 |
| 8.991e-04 | -7.01 | regulation of response to stimulus | biological process | GO:0048583 | 4159 | 88 | 17256 | 270 |
ARHGAP26,ACVR1,DUSP8,LGR4,RASAL2,DOCK1,C4A,PLXNA2,NDRG2,ABAT,COLEC10,PRKCA,ABHD6,CBLN1,TIAM2,PMAIP1,DACT1,CFHR1,DAB2IP,PDE4D,EPHB6,PHLDB2,WISP3,PTPN6,NLGN4X,WNT11,ACVR2B,PLEKHA1,JAM3,TCF7L1,RASGRF2,PLK2,WFS1,RBPMS2,ERN1,WWTR1,PLEKHG1,ARHGAP28,TNFSF15,MAPK13,TMOD2,DISP1,DLX2,RGS16,SCN5A,RUNX2,NECAB2,ARHGEF11,UBASH3B,FBXO4,BIK,RASL11B,GAS6,TNFRSF10C,MYORG,NEO1,MTUS1,IL17D,RGS17,RALGPS2,MYC,PRKCD,RASD2,SRGAP1,INAVA,BNIP3,STXBP1,BARX1,GPR161,PARP9,BDNF,PXN,MSX1,MPP1,SPATA13,WWC1,STRADB,SHISA2,GAREM1,PRDM1,TLR6,GPLD1,TRIB3,FGR,ADAMTS3,MAP2K6,IQSEC2,DDIT3 |
| 9.110e-04 | -7.00 | negative regulation of signaling | biological process | GO:0023057 | 1382 | 37 | 17256 | 270 |
RGS16,RUNX2,ACVR1,DUSP8,LGR4,RASAL2,UBASH3B,RASL11B,NDRG2,GAS6,ABHD6,CBLN1,RGS17,DACT1,MYC,PRKCD,DAB2IP,EPHB6,STXBP1,BARX1,GPR161,PTPN6,WWC1,STRADB,NLGN4X,SHISA2,WNT11,PRDM1,PLEKHA1,TLR6,TRIB3,RBPMS2,WFS1,PLK2,WWTR1,DLX2,DDIT3 |
| 9.140e-04 | -7.00 | pyridine-containing compound biosynthetic process | biological process | GO:0072525 | 72 | 6 | 17256 | 270 |
GAPDH,KMO,ALDOA,PARP9,OGDHL,HK2 |
| 9.210e-04 | -6.99 | MODULE_137 | MSigDB lists | MODULE_137 | 522 | 19 | 17377 | 282 |
ACSL1,DUSP8,PLXNA2,SETBP1,KIF5C,ABAT,KIF21B,DYNC1I1,CBLN1,PLEKHB1,NEO1,MTUS1,GNAO1,MAP7,DBP,APBA2,STXBP1,HSPA2,PKIA |
| 9.294e-04 | -6.98 | salivary_gland-parotid-carcinoma-adenoid_cystic_carcinoma | COSMIC cancer mutations | salivary_gland-parotid-carcinoma-adenoid_cystic_carcinoma | 566 | 20 | 17385 | 281 |
IL17RD,ACVR1,PDK1,ACVR2B,PRKCA,PALLD,CBLN1,NEO1,ZNF827,TRIB3,FGR,PLK2,RPS6KL1,MAP2K6,HK2,SGK1,MAPK13,OR2W3,DNAH5,DDIT3 |
| 9.334e-04 | -6.98 | GO_NEGATIVE_REGULATION_OF_CELL_COMMUNICATION | MSigDB lists | GO_NEGATIVE_REGULATION_OF_CELL_COMMUNICATION | 1143 | 33 | 17377 | 282 |
RGS16,ACVR1,RUNX2,RASAL2,DUSP8,LGR4,UBASH3B,RASL11B,NDRG2,OVOL2,GAS6,ABHD6,RGS17,DACT1,MYC,PRKCD,DAB2IP,STXBP1,BARX1,GPR161,QSOX1,PTPN6,STRADB,WWC1,NLGN4X,WNT11,PLEKHA1,PRDM1,WFS1,PLK2,WWTR1,DLX2,DDIT3 |
| 9.372e-04 | -6.97 | GSE10211_UV_INACT_SENDAI_VS_LIVE_SENDAI_VIRUS_TRACHEAL_EPITHELIAL_CELLS_DN | MSigDB lists | GSE10211_UV_INACT_SENDAI_VS_LIVE_SENDAI_VIRUS_TRACHEAL_EPITHELIAL_CELLS_DN | 154 | 9 | 17377 | 282 |
EPCAM,DYRK1B,MXI1,PNRC1,MARVELD2,MYC,CCDC122,SETBP1,ARRDC4 |
| 9.372e-04 | -6.97 | GSE15659_TREG_VS_TCONV_DN | MSigDB lists | GSE15659_TREG_VS_TCONV_DN | 154 | 9 | 17377 | 282 |
C2orf88,NUMBL,NECAB2,UROS,PDE4D,GAS6,RAB27B,ABHD6,ATP6AP1L |
| 9.372e-04 | -6.97 | ONDER_CDH1_TARGETS_2_DN | MSigDB lists | ONDER_CDH1_TARGETS_2_DN | 442 | 17 | 17377 | 282 |
LGR4,ST14,WISP3,SLC39A8,CYB5R2,BIK,WWC1,OVOL2,RAB38,HERC6,FHOD3,MTUS1,EPCAM,TCF7L1,PLK2,MAP7,MAPK13 |
| 9.455e-04 | -6.96 | GERY_CEBP_TARGETS | MSigDB lists | GERY_CEBP_TARGETS | 124 | 8 | 17377 | 282 |
TRIB3,RGS16,ACSL1,RASL11B,WWC1,ACTA2,DBP,DDIT3 |
| 9.694e-04 | -6.94 | OPRD1 (opioid receptor delta 1) | protein interactions | 4985 | 27 | 4 | 17029 | 283 |
PRKCA,KLHL3,GNAO1,PRKCD |
| 9.752e-04 | -6.93 | CTTTGT_V$LEF1_Q2 | MSigDB lists | CTTTGT_V$LEF1_Q2 | 1828 | 47 | 17377 | 282 |
MXI1,RECK,PTPN21,BIK,SETBP1,RASL11B,NDRG2,FAM198B,SATB1,PFN2,CBLN1,HMCN1,NEO1,MTUS1,ZNF827,NUMBL,KCTD15,DACT1,ZIC5,ZNF521,TRIM3,PRICKLE2,BNIP3,DAB2IP,PDE4D,BARX1,GPR161,MN1,BDNF,MSX1,PNRC1,SLC39A8,BNIP3L,MAFB,WNT11,ACVR2B,TBC1D16,JAM3,RERE,TCF7L1,PLK2,MAP2K6,TMOD2,DBP,THAP10,RNF122,PKIA |
| 9.820e-04 | -6.93 | GSE7460_CTRL_VS_TGFB_TREATED_ACT_TREG_DN | MSigDB lists | GSE7460_CTRL_VS_TGFB_TREATED_ACT_TREG_DN | 187 | 10 | 17377 | 282 |
GPR63,PHLDB2,RGS16,SLC40A1,MAP7,EXOG,TBC1D16,NIPSNAP3B,MTUS1,CTIF |
| 1.011e-03 | -6.90 | GGGAGGRR_V$MAZ_Q6 | MSigDB lists | GGGAGGRR_V$MAZ_Q6 | 2136 | 53 | 17377 | 282 |
SCN5A,MXI1,CCDC148,ACVR1,DUSP8,ZNF395,C4A,BACE1,BLVRB,ARL2,NDRG2,OVOL2,SATB1,HPCAL4,NCS1,NEO1,MTUS1,PPM1E,NUMBL,RPS6KL1,MYC,ZNF521,TRIM3,DAB2IP,EPHB6,PJA1,TSHR,VGLL4,FANK1,BDNF,MSX1,GAPDH,PNRC1,KLHL3,SOX21,BNIP3L,NUAK2,WWC1,TNS1,RAB38,ARRDC4,PLEKHB1,RERE,TCF7L1,ADAMTS3,GNAO1,MAP2K6,ALDOA,P4HA1,TNFSF15,DBP,DDIT3,PHC1 |
| 1.015e-03 | -6.89 | cellular response to drug | biological process | GO:0035690 | 303 | 13 | 17256 | 270 |
PPM1E,MSX1,MYC,PRKCD,ADCY1,MAPK13,ABCC2,BNIP3,ITPR2,GAS6,PLEKHA1,SMYD3,GPLD1 |
| 1.019e-03 | -6.89 | LIM_MAMMARY_LUMINAL_MATURE_DN | MSigDB lists | LIM_MAMMARY_LUMINAL_MATURE_DN | 97 | 7 | 17377 | 282 |
C2orf88,GAS6,MOXD1,RECK,EMILIN2,TIAM2,ZNF521 |
| 1.023e-03 | -6.89 | MODULE_202 | MSigDB lists | MODULE_202 | 28 | 4 | 17377 | 282 |
ACTA2,MYOM2,PFN2,DSTN |
| 1.023e-03 | -6.89 | GSE44732_UNSTIM_VS_IL27_STIM_IMATURE_DC_DN | MSigDB lists | GSE44732_UNSTIM_VS_IL27_STIM_IMATURE_DC_DN | 188 | 10 | 17377 | 282 |
TMEM53,FGR,ACSL1,WFS1,BLVRB,EEPD1,DISP1,ABHD6,PHC1,PGBD5 |
| 1.023e-03 | -6.89 | CAMP_UP.V1_DN | MSigDB lists | CAMP_UP.V1_DN | 188 | 10 | 17377 | 282 |
IQCK,BACE1,RASD2,PRDM1,PALLD,TANC2,TLN2,STXBP1,PKIA,RERE |
| 1.023e-03 | -6.89 | GSE14699_NAIVE_VS_ACT_CD8_TCELL_UP | MSigDB lists | GSE14699_NAIVE_VS_ACT_CD8_TCELL_UP | 188 | 10 | 17377 | 282 |
EPCAM,ST14,RECK,HK2,CYP4V2,P4HA1,NRN1,CEBPA,ARRDC4,ABHD4 |
| 1.023e-03 | -6.89 | GSE39110_UNTREATED_VS_IL2_TREATED_CD8_TCELL_DAY6_POST_IMMUNIZATION_DN | MSigDB lists | GSE39110_UNTREATED_VS_IL2_TREATED_CD8_TCELL_DAY6_POST_IMMUNIZATION_DN | 188 | 10 | 17377 | 282 |
EPB41L5,CCDC126,IFT81,PDK1,WFS1,MAP7,KIF5C,CEBPA,PFN2,SMPDL3A |
| 1.030e-03 | -6.88 | MODULE_66 | MSigDB lists | MODULE_66 | 527 | 19 | 17377 | 282 |
ACSL1,DUSP8,PLXNA2,SETBP1,KIF5C,ABAT,KIF21B,DYNC1I1,CBLN1,PLEKHB1,NEO1,MTUS1,GNAO1,MAP7,DBP,APBA2,STXBP1,HSPA2,PKIA |
| 1.040e-03 | -6.87 | regulation of cellular component biogenesis | biological process | GO:0044087 | 907 | 27 | 17256 | 270 |
EPB41L5,PHLDB2,BDNF,PXN,BIK,ARL2,SLX1B,WNT11,PRKCA,PFN2,TLR6,TBC1D16,CBLN1,FHOD3,PPM1E,PMAIP1,DACT1,PLK2,PRKCD,GTF2F2,ARHGAP28,DAB2IP,TMOD2,STXBP1,COBL,HSPA2,TBC1D8 |
| 1.051e-03 | -6.86 | GO_DIGESTIVE_TRACT_MORPHOGENESIS | MSigDB lists | GO_DIGESTIVE_TRACT_MORPHOGENESIS | 48 | 5 | 17377 | 282 |
EPB41L5,WNT11,ACVR2B,OVOL2,DACT1 |
| 1.053e-03 | -6.86 | DOUGLAS_BMI1_TARGETS_UP | MSigDB lists | DOUGLAS_BMI1_TARGETS_UP | 528 | 19 | 17377 | 282 |
SCAMP1,RASAL2,MPP1,B4GALNT3,TBC1D16,NT5DC2,CENPV,NEO1,KCTD15,KMO,PMAIP1,RBPMS2,HK2,TRIM3,DAB2IP,KIAA0408,RNF122,BARX1,PKIA |
| 1.063e-03 | -6.85 | NUYTTEN_NIPP1_TARGETS_UP | MSigDB lists | NUYTTEN_NIPP1_TARGETS_UP | 698 | 23 | 17377 | 282 |
TMC7,CCDC126,PDK1,KLHL3,CYP2J2,FBXO4,LSM11,BACE1,PTPN21,OGDHL,SETBP1,SATB2,MARVELD2,HK2,GTF2F2,KIAA0513,P4HA1,SGK1,BNIP3,KIAA0408,VGLL4,ATP6AP1L,PARP9 |
| 1.065e-03 | -6.85 | GSE39556_UNTREATED_VS_3H_POLYIC_INJ_MOUSE_NK_CELL_DN | MSigDB lists | GSE39556_UNTREATED_VS_3H_POLYIC_INJ_MOUSE_NK_CELL_DN | 189 | 10 | 17377 | 282 |
MXI1,ACVR1,ACSL1,RECK,MPP1,WFS1,SATB1,PFN2,VGLL4,COBL |
| 1.065e-03 | -6.85 | GSE39916_B_CELL_SPLEEN_VS_PLASMA_CELL_BONE_MARROW_DN | MSigDB lists | GSE39916_B_CELL_SPLEEN_VS_PLASMA_CELL_BONE_MARROW_DN | 189 | 10 | 17377 | 282 |
ARHGAP26,EPB41L5,CCDC126,IFT81,GPR155,ERN1,KIF5C,RNF157,PFN2,SMPDL3A |
| 1.065e-03 | -6.85 | GSE2405_HEAT_KILLED_VS_LIVE_A_PHAGOCYTOPHILUM_STIM_NEUTROPHIL_9H_DN | MSigDB lists | GSE2405_HEAT_KILLED_VS_LIVE_A_PHAGOCYTOPHILUM_STIM_NEUTROPHIL_9H_DN | 189 | 10 | 17377 | 282 |
PPM1E,IFT81,LMLN,SCAMP1,CYP2J2,SLC39A8,PTPN21,PLEKHG1,PDE4D,HSPA2 |
| 1.065e-03 | -6.85 | GSE29618_MONOCYTE_VS_MDC_UP | MSigDB lists | GSE29618_MONOCYTE_VS_MDC_UP | 189 | 10 | 17377 | 282 |
FGR,MXI1,ACSL1,MPP1,BNIP3L,KIAA0513,CLMN,MAFB,FAM198B,TBC1D8 |
| 1.072e-03 | -6.84 | WACKER_HYPOXIA_TARGETS_OF_VHL | MSigDB lists | WACKER_HYPOXIA_TARGETS_OF_VHL | 13 | 3 | 17377 | 282 |
P4HA1,PDK1,HK2 |
| 1.074e-03 | -6.84 | GSE13738_RESTING_VS_BYSTANDER_ACTIVATED_CD4_TCELL_UP | MSigDB lists | GSE13738_RESTING_VS_BYSTANDER_ACTIVATED_CD4_TCELL_UP | 157 | 9 | 17377 | 282 |
SPNS1,SLC40A1,KIAA0355,NDRG2,TMOD2,SHISA2,RAB27B,TANC2,APBA2 |
| 1.075e-03 | -6.84 | GSK3A (glycogen synthase kinase 3 alpha) | protein interactions | 2931 | 70 | 6 | 17029 | 283 |
SGK1,PXN,PRKCA,ARHGEF11,MYC,PRKCD |
| 1.079e-03 | -6.83 | GO_POSITIVE_REGULATION_OF_HYDROLASE_ACTIVITY | MSigDB lists | GO_POSITIVE_REGULATION_OF_HYDROLASE_ACTIVITY | 876 | 27 | 17377 | 282 |
ARHGAP26,RGS16,RASAL2,ARHGEF11,DOCK1,SPATA13,WNT11,TBC1D16,PFN2,TIAM2,GPLD1,RGS17,RALGPS2,PMAIP1,MYC,GNAO1,RASGRF2,PRKCD,ERN1,PLEKHG1,SRGAP1,ARHGAP28,TNFSF15,DAB2IP,IQSEC2,HSPA2,TBC1D8 |
| 1.082e-03 | -6.83 | SHAFFER_IRF4_TARGETS_IN_MYELOMA_VS_MATURE_B_LYMPHOCYTE | MSigDB lists | SHAFFER_IRF4_TARGETS_IN_MYELOMA_VS_MATURE_B_LYMPHOCYTE | 98 | 7 | 17377 | 282 |
P4HA1,PRDM1,MXI1,PDK1,TNFRSF17,MYC,DDIT3 |
| 1.083e-03 | -6.83 | Pkinase_C | pfam domains | PF00433 | 29 | 4 | 17054 | 271 |
SGK1,SGK2,PRKCA,PRKCD |
| 1.108e-03 | -6.81 | GSE20715_0H_VS_48H_OZONE_LUNG_UP | MSigDB lists | GSE20715_0H_VS_48H_OZONE_LUNG_UP | 190 | 10 | 17377 | 282 |
SLC40A1,ZNF395,DACT1,ZNF521,SLC25A28,PLEKHA1,FAM198B,PRDM1,SATB1,PLEKHB1 |
| 1.108e-03 | -6.81 | GSE40273_GATA1_KO_VS_WT_TREG_DN | MSigDB lists | GSE40273_GATA1_KO_VS_WT_TREG_DN | 190 | 10 | 17377 | 282 |
RALGPS2,KMO,SFXN4,PTPN6,ZDHHC23,MAP7,CCDC122,ITPR2,ABHD6,SMPDL3A |
| 1.114e-03 | -6.80 | Pkinase_C | interpro domains | IPR017892 | 29 | 4 | 18492 | 296 |
SGK1,SGK2,PRKCA,PRKCD |
| 1.117e-03 | -6.80 | central_nervous_system-medulla-primitive_neuroectodermal_tumour-medulloblastoma-classic | COSMIC cancer mutations | central_nervous_system-medulla-primitive_neuroectodermal_tumour-medulloblastoma-classic | 15206 | 262 | 17385 | 281 |
ARHGAP26,ACVR1,DUSP8,LGR4,RECK,LSM11,ALG1L,PRKCA,ABHD6,NCS1,EPDR1,PMAIP1,CFHR1,TMEM37,TSHR,TBC1D8,KLHL23,KLHL3,WISP3,EXOC6B,DSTN,BNIP3L,SLC25A28,ABCC2,TNS1,SAV1,SPATA9,PLK2,RASGRF2,ALDOA,ARHGAP28,MAPK13,TMOD2,TANC2,SCN5A,ZHX3,CYP2J2,SLC36A4,TNFRSF10C,DYNC1I1,HPCAL4,NIPSNAP3B,MTUS1,IL17D,RALGPS2,MYC,ZIC5,SRGAP1,MOXD1,STXBP1,GPR161,EPB41L5,BDNF,QSOX1,SHISA2,ARRDC4,ZNF558,ADAMTS3,ISM1,LRRIQ3,QPCTL,EMILIN2,CLMN,IQSEC2,SMYD3,ZNF516,RASAL2,ST14,FAM131C,C4A,CCDC110,PLXNA2,COLEC10,TIAM2,TMEM53,ZNF827,KMO,DACT1,DAB2IP,PJA1,PDE4D,RAB27B,DNAH5,ATP6AP1L,KIAA1549,C3orf67,GAPDH,PDK1,SOX21,CYB5R2,SFXN4,ADCY1,NLGN4X,SATB2,WNT11,RAB38,TBC1D16,IQCK,ZNF697,WFS1,WWTR1,PLEKHG1,TNFSF15,DBP,KLHL31,COBL,KCTD1,CCDC148,MXI1,TMEM132C,BACE1,BIK,CCNJL,KIF5C,ARL2,GAS6,ZNF219,NEO1,RGS17,GPR155,SMPDL3A,PARP9,TMC7,MN1,B9D1,SLC40A1,PXN,MPP1,GPR137C,GPLD1,TRIB3,FGR,GNAO1,MYOM2,TNFRSF17,DDIT3,B4GALT7,PHC1,CCDC126,ACSL1,HEBP1,PTPN21,NDRG2,NRN1,ABAT,ITPR2,SLC2A13,CACNB4,ABHD4,HMCN1,EPCAM,PPM1E,FKBP9,CPNE2,DLX6,TMEM143,TLN2,FANK1,ZNF391,PGBD5,PNRC1,CAPN5,TTC22,PLEKHA1,SGK2,PLEKHB1,NT5DC2,DYRK1B,SPNS1,TCF7L1,DLX2,APBA2,GPR63,LONRF1,RGS16,RUNX2,ZNF395,BVES,FBXO4,UBASH3B,CYP4V2,RASL11B,SETBP1,CHADL,SATB1,PFN2,FHOD3,SLC30A4,GAN,EBF4,BNIP3,NCEH1,VGLL4,BARX1,IL17RD,SPATA13,EFNA3,MAFB,STRADB,WWC1,WDR25,PPFIA4,LHPP,PRDM1,B4GALNT3,KIAA0355,HK2,RNF122,DOCK1,RHPN2,FAM198B,KIF21B,RADIL,CBLN1,KCTD15,RPS6KL1,EEPD1,ZDHHC23,ZNF521,MAP7,MYH15,TMEM120B,HSPA2,FAM78B,PHLDB2,UROS,PTPN6,SLC39A8,JAM3,CENPV,IFT81,LMLN,ANKRD31,RBPMS2,DISP1,NECAB2,PRSS16,ARHGEF11,BLVRB,RASD2,EHD3,PRKCD,GTF2F2,PRICKLE2,TRIM3,SGK1,CCDC122,ACTA2,KIAA0408,MSX1,NUAK2,EXOG,TLR6,CTIF,RERE,FMO4,MAP2K6,KIAA0513,ZNF474,THAP10,RNF157,PKIA |
| 1.117e-03 | -6.80 | central_nervous_system-medulla-primitive_neuroectodermal_tumour-medulloblastoma-desmoplastic | COSMIC cancer mutations | central_nervous_system-medulla-primitive_neuroectodermal_tumour-medulloblastoma-desmoplastic | 15206 | 262 | 17385 | 281 |
ARHGAP26,ACVR1,DUSP8,LGR4,RECK,LSM11,ALG1L,PRKCA,ABHD6,NCS1,EPDR1,PMAIP1,CFHR1,TMEM37,TSHR,TBC1D8,KLHL23,KLHL3,WISP3,EXOC6B,DSTN,BNIP3L,SLC25A28,ABCC2,TNS1,SAV1,SPATA9,PLK2,RASGRF2,ALDOA,ARHGAP28,MAPK13,TMOD2,TANC2,SCN5A,ZHX3,CYP2J2,SLC36A4,TNFRSF10C,DYNC1I1,HPCAL4,NIPSNAP3B,MTUS1,IL17D,RALGPS2,MYC,ZIC5,SRGAP1,MOXD1,STXBP1,GPR161,EPB41L5,BDNF,QSOX1,SHISA2,ARRDC4,ZNF558,ADAMTS3,ISM1,LRRIQ3,QPCTL,EMILIN2,CLMN,IQSEC2,SMYD3,ZNF516,RASAL2,ST14,C4A,FAM131C,CCDC110,PLXNA2,COLEC10,TIAM2,TMEM53,ZNF827,KMO,DACT1,DAB2IP,PJA1,PDE4D,RAB27B,DNAH5,ATP6AP1L,KIAA1549,C3orf67,GAPDH,PDK1,SOX21,CYB5R2,SFXN4,ADCY1,NLGN4X,SATB2,WNT11,RAB38,TBC1D16,IQCK,ZNF697,WFS1,WWTR1,PLEKHG1,TNFSF15,DBP,KLHL31,COBL,KCTD1,CCDC148,MXI1,TMEM132C,BACE1,BIK,CCNJL,KIF5C,ARL2,GAS6,ZNF219,NEO1,RGS17,GPR155,SMPDL3A,PARP9,TMC7,MN1,B9D1,SLC40A1,PXN,MPP1,GPR137C,GPLD1,TRIB3,FGR,GNAO1,MYOM2,TNFRSF17,DDIT3,B4GALT7,PHC1,CCDC126,ACSL1,HEBP1,PTPN21,NDRG2,NRN1,ABAT,ITPR2,SLC2A13,CACNB4,ABHD4,HMCN1,EPCAM,PPM1E,FKBP9,CPNE2,DLX6,TMEM143,TLN2,FANK1,ZNF391,PGBD5,PNRC1,CAPN5,TTC22,PLEKHA1,SGK2,PLEKHB1,NT5DC2,DYRK1B,SPNS1,TCF7L1,DLX2,APBA2,GPR63,LONRF1,RGS16,RUNX2,ZNF395,BVES,FBXO4,UBASH3B,CYP4V2,RASL11B,SETBP1,CHADL,SATB1,PFN2,FHOD3,SLC30A4,GAN,EBF4,BNIP3,NCEH1,VGLL4,BARX1,IL17RD,SPATA13,EFNA3,MAFB,STRADB,WWC1,WDR25,PPFIA4,LHPP,PRDM1,B4GALNT3,KIAA0355,HK2,RNF122,DOCK1,RHPN2,FAM198B,KIF21B,RADIL,CBLN1,KCTD15,RPS6KL1,ZDHHC23,EEPD1,ZNF521,MAP7,MYH15,TMEM120B,HSPA2,FAM78B,PHLDB2,UROS,PTPN6,SLC39A8,JAM3,CENPV,IFT81,LMLN,ANKRD31,RBPMS2,DISP1,NECAB2,PRSS16,ARHGEF11,BLVRB,RASD2,EHD3,PRKCD,GTF2F2,PRICKLE2,TRIM3,SGK1,CCDC122,ACTA2,KIAA0408,MSX1,NUAK2,EXOG,TLR6,CTIF,RERE,FMO4,MAP2K6,KIAA0513,ZNF474,THAP10,RNF157,PKIA |
| 1.117e-03 | -6.80 | central_nervous_system-medulla-primitive_neuroectodermal_tumour-medulloblastoma-large_cell | COSMIC cancer mutations | central_nervous_system-medulla-primitive_neuroectodermal_tumour-medulloblastoma-large_cell | 15206 | 262 | 17385 | 281 |
ARHGAP26,ACVR1,DUSP8,LGR4,RECK,LSM11,ALG1L,PRKCA,ABHD6,NCS1,EPDR1,PMAIP1,CFHR1,TMEM37,TSHR,TBC1D8,KLHL23,KLHL3,WISP3,EXOC6B,DSTN,BNIP3L,SLC25A28,ABCC2,TNS1,SAV1,SPATA9,PLK2,RASGRF2,ALDOA,ARHGAP28,MAPK13,TMOD2,TANC2,SCN5A,ZHX3,CYP2J2,SLC36A4,TNFRSF10C,DYNC1I1,HPCAL4,NIPSNAP3B,MTUS1,IL17D,RALGPS2,MYC,ZIC5,SRGAP1,MOXD1,STXBP1,GPR161,EPB41L5,BDNF,QSOX1,SHISA2,ARRDC4,ZNF558,ADAMTS3,ISM1,LRRIQ3,QPCTL,EMILIN2,CLMN,IQSEC2,SMYD3,ZNF516,RASAL2,ST14,FAM131C,C4A,CCDC110,PLXNA2,COLEC10,TIAM2,TMEM53,ZNF827,KMO,DACT1,DAB2IP,PJA1,PDE4D,RAB27B,DNAH5,ATP6AP1L,KIAA1549,C3orf67,GAPDH,PDK1,SOX21,CYB5R2,SFXN4,ADCY1,NLGN4X,SATB2,WNT11,RAB38,TBC1D16,IQCK,ZNF697,WFS1,WWTR1,PLEKHG1,TNFSF15,DBP,KLHL31,COBL,KCTD1,CCDC148,MXI1,TMEM132C,BACE1,BIK,CCNJL,KIF5C,ARL2,GAS6,ZNF219,NEO1,RGS17,GPR155,SMPDL3A,PARP9,TMC7,MN1,B9D1,SLC40A1,PXN,MPP1,GPR137C,GPLD1,TRIB3,FGR,GNAO1,MYOM2,TNFRSF17,DDIT3,B4GALT7,PHC1,CCDC126,ACSL1,HEBP1,PTPN21,NDRG2,NRN1,ABAT,ITPR2,SLC2A13,CACNB4,ABHD4,HMCN1,EPCAM,PPM1E,FKBP9,CPNE2,DLX6,TMEM143,TLN2,FANK1,ZNF391,PGBD5,PNRC1,CAPN5,TTC22,PLEKHA1,SGK2,PLEKHB1,NT5DC2,DYRK1B,SPNS1,TCF7L1,DLX2,APBA2,GPR63,LONRF1,RGS16,RUNX2,ZNF395,BVES,FBXO4,UBASH3B,CYP4V2,RASL11B,SETBP1,CHADL,SATB1,PFN2,FHOD3,SLC30A4,GAN,EBF4,BNIP3,NCEH1,VGLL4,BARX1,IL17RD,SPATA13,EFNA3,MAFB,STRADB,WWC1,WDR25,PPFIA4,LHPP,PRDM1,B4GALNT3,KIAA0355,HK2,RNF122,DOCK1,RHPN2,FAM198B,KIF21B,RADIL,CBLN1,KCTD15,RPS6KL1,EEPD1,ZDHHC23,ZNF521,MAP7,MYH15,TMEM120B,HSPA2,FAM78B,PHLDB2,UROS,PTPN6,SLC39A8,JAM3,CENPV,IFT81,LMLN,ANKRD31,RBPMS2,DISP1,NECAB2,PRSS16,ARHGEF11,BLVRB,RASD2,EHD3,PRKCD,GTF2F2,PRICKLE2,TRIM3,SGK1,CCDC122,ACTA2,KIAA0408,MSX1,NUAK2,EXOG,TLR6,CTIF,RERE,FMO4,MAP2K6,KIAA0513,ZNF474,THAP10,RNF157,PKIA |
| 1.117e-03 | -6.80 | central_nervous_system-medulla-primitive_neuroectodermal_tumour-medulloblastoma | COSMIC cancer mutations | central_nervous_system-medulla-primitive_neuroectodermal_tumour-medulloblastoma | 15206 | 262 | 17385 | 281 |
ARHGAP26,ACVR1,DUSP8,LGR4,RECK,LSM11,ALG1L,PRKCA,ABHD6,NCS1,EPDR1,PMAIP1,CFHR1,TMEM37,TSHR,TBC1D8,KLHL23,KLHL3,WISP3,EXOC6B,DSTN,BNIP3L,SLC25A28,ABCC2,TNS1,SAV1,SPATA9,PLK2,RASGRF2,ALDOA,ARHGAP28,MAPK13,TMOD2,TANC2,SCN5A,ZHX3,CYP2J2,SLC36A4,TNFRSF10C,DYNC1I1,HPCAL4,NIPSNAP3B,MTUS1,IL17D,RALGPS2,MYC,ZIC5,SRGAP1,MOXD1,STXBP1,GPR161,EPB41L5,BDNF,QSOX1,SHISA2,ARRDC4,ZNF558,ADAMTS3,ISM1,LRRIQ3,QPCTL,EMILIN2,CLMN,IQSEC2,SMYD3,ZNF516,RASAL2,ST14,FAM131C,C4A,CCDC110,PLXNA2,COLEC10,TIAM2,TMEM53,ZNF827,KMO,DACT1,DAB2IP,PJA1,PDE4D,RAB27B,DNAH5,ATP6AP1L,KIAA1549,C3orf67,GAPDH,PDK1,SOX21,CYB5R2,SFXN4,ADCY1,NLGN4X,SATB2,WNT11,RAB38,TBC1D16,IQCK,ZNF697,WFS1,WWTR1,PLEKHG1,TNFSF15,DBP,KLHL31,COBL,KCTD1,CCDC148,MXI1,TMEM132C,BACE1,BIK,CCNJL,KIF5C,ARL2,GAS6,ZNF219,NEO1,RGS17,GPR155,SMPDL3A,PARP9,TMC7,MN1,B9D1,SLC40A1,PXN,MPP1,GPR137C,GPLD1,TRIB3,FGR,GNAO1,MYOM2,TNFRSF17,DDIT3,B4GALT7,PHC1,CCDC126,ACSL1,HEBP1,PTPN21,NDRG2,NRN1,ABAT,ITPR2,SLC2A13,CACNB4,ABHD4,HMCN1,EPCAM,PPM1E,FKBP9,CPNE2,DLX6,TMEM143,TLN2,FANK1,ZNF391,PGBD5,PNRC1,CAPN5,TTC22,PLEKHA1,SGK2,PLEKHB1,NT5DC2,DYRK1B,SPNS1,TCF7L1,DLX2,APBA2,GPR63,LONRF1,RGS16,RUNX2,ZNF395,BVES,FBXO4,UBASH3B,CYP4V2,RASL11B,SETBP1,CHADL,SATB1,PFN2,FHOD3,SLC30A4,GAN,EBF4,BNIP3,NCEH1,VGLL4,BARX1,IL17RD,SPATA13,EFNA3,MAFB,STRADB,WWC1,WDR25,PPFIA4,LHPP,PRDM1,B4GALNT3,KIAA0355,HK2,RNF122,DOCK1,RHPN2,FAM198B,KIF21B,RADIL,CBLN1,KCTD15,RPS6KL1,EEPD1,ZDHHC23,ZNF521,MAP7,MYH15,TMEM120B,HSPA2,FAM78B,PHLDB2,UROS,PTPN6,SLC39A8,JAM3,CENPV,IFT81,LMLN,ANKRD31,RBPMS2,DISP1,NECAB2,PRSS16,ARHGEF11,BLVRB,RASD2,EHD3,PRKCD,GTF2F2,PRICKLE2,TRIM3,SGK1,CCDC122,ACTA2,KIAA0408,MSX1,NUAK2,EXOG,TLR6,CTIF,RERE,FMO4,MAP2K6,KIAA0513,ZNF474,THAP10,RNF157,PKIA |
| 1.123e-03 | -6.79 | BERTUCCI_MEDULLARY_VS_DUCTAL_BREAST_CANCER_DN | MSigDB lists | BERTUCCI_MEDULLARY_VS_DUCTAL_BREAST_CANCER_DN | 158 | 9 | 17377 | 282 |
FKBP9,ACVR1,CAPN5,PTPN21,EFNA3,ACTA2,TLN2,SAV1,KCTD1 |
| 1.127e-03 | -6.79 | ENK_UV_RESPONSE_EPIDERMIS_DN | MSigDB lists | ENK_UV_RESPONSE_EPIDERMIS_DN | 490 | 18 | 17377 | 282 |
ACSL1,PNRC1,DUSP8,ST14,CYP2J2,HEBP1,PTPN21,PLXNA2,GAS6,SATB1,NEO1,PRKCD,HK2,GAN,DBP,EPHB6,STXBP1,PKIA |
| 1.127e-03 | -6.79 | classic | COSMIC cancer mutations | classic | 15207 | 262 | 17385 | 281 |
ARHGAP26,ACVR1,DUSP8,LGR4,RECK,LSM11,ALG1L,PRKCA,ABHD6,NCS1,EPDR1,PMAIP1,CFHR1,TMEM37,TSHR,TBC1D8,KLHL23,KLHL3,WISP3,EXOC6B,DSTN,BNIP3L,SLC25A28,ABCC2,TNS1,SAV1,SPATA9,PLK2,RASGRF2,ALDOA,ARHGAP28,MAPK13,TMOD2,TANC2,SCN5A,ZHX3,CYP2J2,SLC36A4,TNFRSF10C,DYNC1I1,HPCAL4,NIPSNAP3B,MTUS1,IL17D,RALGPS2,MYC,ZIC5,SRGAP1,MOXD1,STXBP1,GPR161,EPB41L5,BDNF,QSOX1,SHISA2,ARRDC4,ZNF558,ADAMTS3,ISM1,LRRIQ3,QPCTL,EMILIN2,CLMN,IQSEC2,SMYD3,ZNF516,RASAL2,ST14,FAM131C,C4A,CCDC110,PLXNA2,COLEC10,TIAM2,TMEM53,ZNF827,KMO,DACT1,DAB2IP,PJA1,PDE4D,RAB27B,DNAH5,ATP6AP1L,KIAA1549,C3orf67,GAPDH,PDK1,SOX21,CYB5R2,SFXN4,ADCY1,NLGN4X,SATB2,WNT11,RAB38,TBC1D16,IQCK,ZNF697,WFS1,WWTR1,PLEKHG1,TNFSF15,DBP,KLHL31,COBL,KCTD1,CCDC148,MXI1,TMEM132C,BACE1,BIK,CCNJL,KIF5C,ARL2,GAS6,ZNF219,NEO1,RGS17,GPR155,SMPDL3A,PARP9,TMC7,MN1,B9D1,SLC40A1,PXN,MPP1,GPR137C,GPLD1,TRIB3,FGR,GNAO1,MYOM2,TNFRSF17,DDIT3,B4GALT7,PHC1,CCDC126,ACSL1,HEBP1,PTPN21,NDRG2,NRN1,ABAT,ITPR2,SLC2A13,CACNB4,ABHD4,HMCN1,EPCAM,PPM1E,FKBP9,CPNE2,DLX6,TMEM143,TLN2,FANK1,ZNF391,PGBD5,PNRC1,CAPN5,TTC22,PLEKHA1,SGK2,PLEKHB1,NT5DC2,DYRK1B,SPNS1,TCF7L1,DLX2,APBA2,GPR63,LONRF1,RGS16,RUNX2,ZNF395,BVES,FBXO4,UBASH3B,CYP4V2,RASL11B,SETBP1,CHADL,SATB1,PFN2,FHOD3,SLC30A4,GAN,EBF4,BNIP3,NCEH1,VGLL4,BARX1,IL17RD,SPATA13,EFNA3,MAFB,STRADB,WWC1,WDR25,PPFIA4,LHPP,PRDM1,B4GALNT3,KIAA0355,HK2,RNF122,DOCK1,RHPN2,FAM198B,KIF21B,RADIL,CBLN1,KCTD15,RPS6KL1,EEPD1,ZDHHC23,ZNF521,MAP7,MYH15,TMEM120B,HSPA2,FAM78B,PHLDB2,UROS,PTPN6,SLC39A8,JAM3,CENPV,IFT81,LMLN,ANKRD31,RBPMS2,DISP1,NECAB2,PRSS16,ARHGEF11,BLVRB,RASD2,EHD3,PRKCD,GTF2F2,PRICKLE2,TRIM3,SGK1,CCDC122,ACTA2,KIAA0408,MSX1,NUAK2,EXOG,TLR6,CTIF,RERE,FMO4,MAP2K6,KIAA0513,ZNF474,THAP10,RNF157,PKIA |
| 1.142e-03 | -6.78 | positive regulation of metabolic process | biological process | GO:0009893 | 3331 | 73 | 17256 | 270 |
ACSL1,ZNF516,ACVR1,LGR4,CEBPA,ABAT,PRKCA,ABHD6,EPCAM,PMAIP1,DACT1,DAB2IP,EPHB6,TSHR,FANK1,HSPA2,SOX21,BNIP3L,ADCY1,WNT11,SATB2,PXYLP1,ACVR2B,DYRK1B,PLK2,WFS1,ERN1,WWTR1,TNFSF15,DLX2,DBP,LONRF1,NECAB2,RUNX2,BVES,ARHGEF11,FBXO4,SLX1B,OVOL2,TNFRSF10C,GAS6,ZNF219,PFN2,KDM7A,MYC,PRKCD,RASD2,EBF4,GTF2F2,ACTA2,INAVA,BNIP3,BARX1,GPR161,PARP9,SLC40A1,MSX1,EFNA3,WWC1,MAFB,STRADB,GAREM1,PRDM1,ARRDC4,TLR6,GPLD1,RERE,TRIB3,FGR,MAP2K6,HK2,SMYD3,DDIT3 |
| 1.144e-03 | -6.77 | Glycolysis | SMPDB pathways | SMP00040 | 15 | 3 | 992 | 15 |
GAPDH,ALDOA,HK2 |
| 1.144e-03 | -6.77 | Glycogenosis- Type VII. Tarui disease | SMPDB pathways | SMP00531 | 15 | 3 | 992 | 15 |
GAPDH,ALDOA,HK2 |
| 1.144e-03 | -6.77 | Fanconi-bickel syndrome | SMPDB pathways | SMP00572 | 15 | 3 | 992 | 15 |
GAPDH,ALDOA,HK2 |
| 1.156e-03 | -6.76 | GNF2_RTN1 | MSigDB lists | GNF2_RTN1 | 49 | 5 | 17377 | 282 |
KIF5C,STXBP1,DYNC1I1,GNAO1,ADCY1 |
| 1.159e-03 | -6.76 | SENESE_HDAC1_TARGETS_DN | MSigDB lists | SENESE_HDAC1_TARGETS_DN | 225 | 11 | 17377 | 282 |
EPB41L5,ZNF827,PHLDB2,RUNX2,ZNF395,BNIP3L,TNS1,PRKCA,GPR137C,TMEM120B,TIAM2 |
| 1.169e-03 | -6.75 | medulla | COSMIC cancer mutations | medulla | 15211 | 262 | 17385 | 281 |
ARHGAP26,ACVR1,DUSP8,LGR4,RECK,LSM11,ALG1L,PRKCA,ABHD6,NCS1,EPDR1,PMAIP1,CFHR1,TMEM37,TSHR,TBC1D8,KLHL23,KLHL3,WISP3,EXOC6B,DSTN,BNIP3L,SLC25A28,ABCC2,TNS1,SAV1,SPATA9,PLK2,RASGRF2,ALDOA,ARHGAP28,MAPK13,TMOD2,TANC2,SCN5A,ZHX3,CYP2J2,SLC36A4,TNFRSF10C,DYNC1I1,HPCAL4,NIPSNAP3B,MTUS1,IL17D,RALGPS2,MYC,ZIC5,SRGAP1,MOXD1,STXBP1,GPR161,EPB41L5,BDNF,QSOX1,SHISA2,ARRDC4,ZNF558,ADAMTS3,ISM1,LRRIQ3,QPCTL,EMILIN2,CLMN,IQSEC2,SMYD3,ZNF516,RASAL2,ST14,FAM131C,C4A,CCDC110,PLXNA2,COLEC10,TIAM2,TMEM53,ZNF827,KMO,DACT1,DAB2IP,PJA1,PDE4D,RAB27B,DNAH5,ATP6AP1L,KIAA1549,C3orf67,GAPDH,PDK1,SOX21,CYB5R2,SFXN4,ADCY1,NLGN4X,SATB2,WNT11,RAB38,TBC1D16,IQCK,ZNF697,WFS1,WWTR1,PLEKHG1,TNFSF15,DBP,KLHL31,COBL,KCTD1,CCDC148,MXI1,TMEM132C,BACE1,BIK,CCNJL,KIF5C,ARL2,GAS6,ZNF219,NEO1,RGS17,GPR155,SMPDL3A,PARP9,TMC7,MN1,B9D1,SLC40A1,PXN,MPP1,GPR137C,GPLD1,TRIB3,FGR,GNAO1,MYOM2,TNFRSF17,DDIT3,B4GALT7,PHC1,CCDC126,ACSL1,HEBP1,PTPN21,NDRG2,NRN1,ABAT,ITPR2,SLC2A13,CACNB4,ABHD4,HMCN1,EPCAM,PPM1E,FKBP9,CPNE2,DLX6,TMEM143,TLN2,FANK1,ZNF391,PGBD5,PNRC1,CAPN5,TTC22,PLEKHA1,SGK2,PLEKHB1,NT5DC2,DYRK1B,SPNS1,TCF7L1,DLX2,APBA2,GPR63,LONRF1,RGS16,RUNX2,ZNF395,BVES,FBXO4,UBASH3B,CYP4V2,RASL11B,SETBP1,CHADL,SATB1,PFN2,FHOD3,SLC30A4,GAN,EBF4,BNIP3,NCEH1,VGLL4,BARX1,IL17RD,SPATA13,EFNA3,MAFB,STRADB,WWC1,WDR25,PPFIA4,LHPP,PRDM1,B4GALNT3,KIAA0355,HK2,RNF122,DOCK1,RHPN2,FAM198B,KIF21B,RADIL,CBLN1,KCTD15,RPS6KL1,EEPD1,ZDHHC23,ZNF521,MAP7,MYH15,TMEM120B,HSPA2,FAM78B,PHLDB2,UROS,PTPN6,SLC39A8,JAM3,CENPV,IFT81,LMLN,ANKRD31,RBPMS2,DISP1,NECAB2,PRSS16,ARHGEF11,BLVRB,RASD2,EHD3,PRKCD,GTF2F2,PRICKLE2,TRIM3,SGK1,CCDC122,ACTA2,KIAA0408,MSX1,NUAK2,EXOG,TLR6,CTIF,RERE,FMO4,MAP2K6,KIAA0513,ZNF474,THAP10,RNF157,PKIA |
| 1.171e-03 | -6.75 | GO_REGULATION_OF_PLATELET_ACTIVATION | MSigDB lists | GO_REGULATION_OF_PLATELET_ACTIVATION | 29 | 4 | 17377 | 282 |
ABAT,PRKCA,UBASH3B,PRKCD |
| 1.179e-03 | -6.74 | PROTEIN_KINASE_DOM | prosite domains | PS50011 | 480 | 18 | 12060 | 202 |
ACVR1,NUAK2,STRADB,ACVR2B,SGK2,PRKCA,GRK3,DYRK1B,TRIB3,FGR,MAP2K6,PLK2,RPS6KL1,PRKCD,ERN1,SGK1,MAPK13,EPHB6 |
| 1.179e-03 | -6.74 | NAD biosynthetic process | biological process | GO:0009435 | 51 | 5 | 17256 | 270 |
GAPDH,KMO,ALDOA,PARP9,HK2 |
| 1.180e-03 | -6.74 | desmoplastic | COSMIC cancer mutations | desmoplastic | 15212 | 262 | 17385 | 281 |
ARHGAP26,ACVR1,DUSP8,LGR4,RECK,LSM11,ALG1L,PRKCA,ABHD6,NCS1,EPDR1,PMAIP1,CFHR1,TMEM37,TSHR,TBC1D8,KLHL23,KLHL3,WISP3,EXOC6B,DSTN,BNIP3L,SLC25A28,ABCC2,TNS1,SAV1,SPATA9,PLK2,RASGRF2,ALDOA,ARHGAP28,MAPK13,TMOD2,TANC2,SCN5A,ZHX3,CYP2J2,SLC36A4,TNFRSF10C,DYNC1I1,HPCAL4,NIPSNAP3B,MTUS1,IL17D,RALGPS2,MYC,ZIC5,SRGAP1,MOXD1,STXBP1,GPR161,EPB41L5,BDNF,QSOX1,SHISA2,ARRDC4,ZNF558,ADAMTS3,ISM1,LRRIQ3,QPCTL,EMILIN2,CLMN,IQSEC2,SMYD3,ZNF516,RASAL2,ST14,C4A,FAM131C,CCDC110,PLXNA2,COLEC10,TIAM2,TMEM53,ZNF827,KMO,DACT1,DAB2IP,PJA1,PDE4D,RAB27B,DNAH5,ATP6AP1L,KIAA1549,C3orf67,GAPDH,PDK1,SOX21,CYB5R2,SFXN4,ADCY1,NLGN4X,SATB2,WNT11,RAB38,TBC1D16,IQCK,ZNF697,WFS1,WWTR1,PLEKHG1,TNFSF15,DBP,KLHL31,COBL,KCTD1,CCDC148,MXI1,TMEM132C,BACE1,BIK,CCNJL,KIF5C,ARL2,GAS6,ZNF219,NEO1,RGS17,GPR155,SMPDL3A,PARP9,TMC7,MN1,B9D1,SLC40A1,PXN,MPP1,GPR137C,GPLD1,TRIB3,FGR,GNAO1,MYOM2,TNFRSF17,DDIT3,B4GALT7,PHC1,CCDC126,ACSL1,HEBP1,PTPN21,NDRG2,NRN1,ABAT,ITPR2,SLC2A13,CACNB4,ABHD4,HMCN1,EPCAM,PPM1E,FKBP9,CPNE2,DLX6,TMEM143,TLN2,FANK1,ZNF391,PGBD5,PNRC1,CAPN5,TTC22,PLEKHA1,SGK2,PLEKHB1,NT5DC2,DYRK1B,SPNS1,TCF7L1,DLX2,APBA2,GPR63,LONRF1,RGS16,RUNX2,ZNF395,BVES,FBXO4,UBASH3B,CYP4V2,RASL11B,SETBP1,CHADL,SATB1,PFN2,FHOD3,SLC30A4,GAN,EBF4,BNIP3,NCEH1,VGLL4,BARX1,IL17RD,SPATA13,EFNA3,MAFB,STRADB,WWC1,WDR25,PPFIA4,LHPP,PRDM1,B4GALNT3,KIAA0355,HK2,RNF122,DOCK1,RHPN2,FAM198B,KIF21B,RADIL,CBLN1,KCTD15,RPS6KL1,ZDHHC23,EEPD1,ZNF521,MAP7,MYH15,TMEM120B,HSPA2,FAM78B,PHLDB2,UROS,PTPN6,SLC39A8,JAM3,CENPV,IFT81,LMLN,ANKRD31,RBPMS2,DISP1,NECAB2,PRSS16,ARHGEF11,BLVRB,RASD2,EHD3,PRKCD,GTF2F2,PRICKLE2,TRIM3,SGK1,CCDC122,ACTA2,KIAA0408,MSX1,NUAK2,EXOG,TLR6,CTIF,RERE,FMO4,MAP2K6,KIAA0513,ZNF474,THAP10,RNF157,PKIA |
| 1.186e-03 | -6.74 | GO_ODONTOGENESIS_OF_DENTIN_CONTAINING_TOOTH | MSigDB lists | GO_ODONTOGENESIS_OF_DENTIN_CONTAINING_TOOTH | 73 | 6 | 17377 | 282 |
ENAM,SCN5A,MSX1,ACVR2B,DLX2,RUNX2 |
| 1.196e-03 | -6.73 | clear_cell_renal_cell_carcinoma | COSMIC cancer mutations | clear_cell_renal_cell_carcinoma | 14301 | 250 | 17385 | 281 |
ARHGAP26,CCDC126,ACSL1,ACVR1,DUSP8,LGR4,RECK,HEBP1,LSM11,PTPN21,NDRG2,NRN1,CEBPA,SLC2A13,ITPR2,ABAT,PRKCA,CACNB4,ABHD6,HMCN1,NCS1,EPDR1,EPCAM,CPNE2,FKBP9,PPM1E,PMAIP1,DLX6,MARVELD2,CFHR1,TMEM143,TMEM37,TLN2,OR2W3,TSHR,FANK1,TBC1D8,PGBD5,PNRC1,KLHL23,KLHL3,EXOC6B,CAPN5,BNIP3L,SLC25A28,TTC22,ABCC2,TNS1,PLEKHA1,ACVR2B,SGK2,SAV1,PLEKHB1,SPNS1,DYRK1B,SPATA9,TCF7L1,PLK2,RASGRF2,ERN1,ALDOA,ARHGAP28,MAPK13,TMOD2,TANC2,APBA2,LONRF1,GPR63,SCN5A,RGS16,TMEM63C,RUNX2,ZNF395,ZHX3,BVES,UBASH3B,CYP2J2,FBXO4,CYP4V2,SETBP1,ATP6V1E2,CHADL,SLC36A4,TNFRSF10C,SATB1,DYNC1I1,NIPSNAP3B,FHOD3,MTUS1,NUMBL,RALGPS2,MYC,ZIC5,EBF4,SRGAP1,GAN,BNIP3,NCEH1,MOXD1,VGLL4,STXBP1,GPR161,EPB41L5,BDNF,IL17RD,QSOX1,SPATA13,PPFIA4,WDR25,WWC1,STRADB,MAFB,SHISA2,PRDM1,LHPP,ARRDC4,OR11H4,B4GALNT3,ADAMTS3,KIAA0355,ISM1,LRRIQ3,QPCTL,EMILIN2,HK2,CLMN,IQSEC2,RNF122,SMYD3,ZNF516,RASAL2,DOCK1,ST14,FAM131C,C4A,CCDC110,PLXNA2,RHPN2,FAM198B,COLEC10,KIF21B,RADIL,CBLN1,TIAM2,TMEM53,ZNF827,KCTD15,KMO,RPS6KL1,DACT1,ZNF521,ZDHHC23,EEPD1,MAP7,DAB2IP,MYH15,PJA1,PDE4D,RAB27B,DNAH5,FAM78B,ATP6AP1L,KIAA1549,HSPA2,C3orf67,DZANK1,PHLDB2,GAPDH,PDK1,SLC39A8,SOX21,PTPN6,CYB5R2,SFXN4,ADCY1,NLGN4X,SATB2,WNT11,RAB38,TBC1D16,JAM3,IQCK,LMLN,ANKRD31,WFS1,RBPMS2,WWTR1,PLEKHG1,P4HA1,TNFSF15,DISP1,DBP,KLHL31,COBL,KCTD1,C2orf88,CCDC148,MXI1,TMEM132C,NECAB2,PRSS16,ARHGEF11,BIK,BLVRB,CCNJL,KIF5C,ARL2,OVOL2,GAS6,ZNF219,NEO1,RGS17,GPR155,PRKCD,EHD3,RASD2,GTF2F2,CCDC122,TRIM3,PRICKLE2,SGK1,KIAA0408,PARP9,TMC7,MN1,SLC40A1,PXN,MPP1,OGDHL,NUAK2,PALLD,EXOG,TLR6,GPR137C,RERE,GPLD1,CTIF,TRIB3,FGR,MAP2K6,GNAO1,FMO4,KIAA0513,MYOM2,TNFRSF17,THAP10,RNF157,PKIA,DDIT3,PHC1 |
| 1.196e-03 | -6.73 | kidney-carcinoma-clear_cell_renal_cell_carcinoma | COSMIC cancer mutations | kidney-carcinoma-clear_cell_renal_cell_carcinoma | 14301 | 250 | 17385 | 281 |
ARHGAP26,CCDC126,ACSL1,ACVR1,DUSP8,LGR4,RECK,HEBP1,LSM11,PTPN21,NDRG2,NRN1,CEBPA,SLC2A13,ITPR2,ABAT,PRKCA,CACNB4,ABHD6,HMCN1,NCS1,EPDR1,EPCAM,CPNE2,FKBP9,PPM1E,PMAIP1,DLX6,MARVELD2,CFHR1,TMEM143,TMEM37,TLN2,OR2W3,TSHR,FANK1,TBC1D8,PGBD5,PNRC1,KLHL23,KLHL3,EXOC6B,CAPN5,BNIP3L,SLC25A28,TTC22,ABCC2,TNS1,PLEKHA1,ACVR2B,SGK2,SAV1,PLEKHB1,SPNS1,DYRK1B,SPATA9,TCF7L1,PLK2,RASGRF2,ERN1,ALDOA,ARHGAP28,MAPK13,TMOD2,TANC2,APBA2,LONRF1,GPR63,SCN5A,RGS16,TMEM63C,RUNX2,ZNF395,ZHX3,BVES,UBASH3B,CYP2J2,FBXO4,CYP4V2,SETBP1,ATP6V1E2,CHADL,SLC36A4,TNFRSF10C,SATB1,DYNC1I1,NIPSNAP3B,FHOD3,MTUS1,NUMBL,RALGPS2,MYC,ZIC5,EBF4,SRGAP1,GAN,BNIP3,NCEH1,MOXD1,VGLL4,STXBP1,GPR161,EPB41L5,BDNF,IL17RD,QSOX1,SPATA13,PPFIA4,WDR25,WWC1,STRADB,MAFB,SHISA2,PRDM1,LHPP,ARRDC4,OR11H4,B4GALNT3,ADAMTS3,KIAA0355,ISM1,LRRIQ3,QPCTL,EMILIN2,HK2,CLMN,IQSEC2,RNF122,SMYD3,ZNF516,RASAL2,DOCK1,ST14,FAM131C,C4A,CCDC110,PLXNA2,RHPN2,FAM198B,COLEC10,KIF21B,RADIL,CBLN1,TIAM2,TMEM53,ZNF827,KCTD15,KMO,RPS6KL1,DACT1,ZNF521,ZDHHC23,EEPD1,MAP7,DAB2IP,MYH15,PJA1,PDE4D,RAB27B,DNAH5,FAM78B,ATP6AP1L,KIAA1549,HSPA2,C3orf67,DZANK1,PHLDB2,GAPDH,PDK1,SLC39A8,SOX21,PTPN6,CYB5R2,SFXN4,ADCY1,NLGN4X,SATB2,WNT11,RAB38,TBC1D16,JAM3,IQCK,LMLN,ANKRD31,WFS1,RBPMS2,WWTR1,PLEKHG1,P4HA1,TNFSF15,DISP1,DBP,KLHL31,COBL,KCTD1,C2orf88,CCDC148,MXI1,TMEM132C,NECAB2,PRSS16,ARHGEF11,BIK,BLVRB,CCNJL,KIF5C,ARL2,OVOL2,GAS6,ZNF219,NEO1,RGS17,GPR155,PRKCD,EHD3,RASD2,GTF2F2,CCDC122,TRIM3,PRICKLE2,SGK1,KIAA0408,PARP9,TMC7,MN1,SLC40A1,PXN,MPP1,OGDHL,NUAK2,PALLD,EXOG,TLR6,GPR137C,RERE,GPLD1,CTIF,TRIB3,FGR,MAP2K6,GNAO1,FMO4,KIAA0513,MYOM2,TNFRSF17,THAP10,RNF157,PKIA,DDIT3,PHC1 |
| 1.208e-03 | -6.72 | cellular component morphogenesis | biological process | GO:0032989 | 777 | 24 | 17256 | 270 |
EPB41L5,BDNF,MSX1,BVES,ST14,PTPN6,PLXNA2,EFNA3,ADCY1,KIF5C,STRADB,PRKCA,PALLD,RADIL,FHOD3,RERE,NEO1,NUMBL,SGK1,MYOM2,DAB2IP,TMOD2,STXBP1,COBL |
| 1.214e-03 | -6.71 | negative regulation of homotypic cell-cell adhesion | biological process | GO:0034111 | 14 | 3 | 17256 | 270 |
ABAT,UBASH3B,PRKCD |
| 1.214e-03 | -6.71 | mitochondrial outer membrane permeabilization | biological process | GO:0097345 | 14 | 3 | 17256 | 270 |
BNIP3,PMAIP1,BNIP3L |
| 1.227e-03 | -6.70 | GSE32986_GMCSF_VS_GMCSF_AND_CURDLAN_LOWDOSE_STIM_DC_DN | MSigDB lists | GSE32986_GMCSF_VS_GMCSF_AND_CURDLAN_LOWDOSE_STIM_DC_DN | 160 | 9 | 17377 | 282 |
PDK1,RALGPS2,MPP1,NUAK2,NDRG2,PRKCA,APBA2,RNF157,CENPV |
| 1.236e-03 | -6.70 | transition metal ion homeostasis | biological process | GO:0055076 | 134 | 8 | 17256 | 270 |
SLC40A1,SLC25A28,SLC30A4,SLC39A8,MYC,SFXN4,ATOX1,NEO1 |
| 1.255e-03 | -6.68 | lung-carcinoma-small_cell_carcinoma | COSMIC cancer mutations | lung-carcinoma-small_cell_carcinoma | 10147 | 189 | 17385 | 281 |
ARHGAP26,ACSL1,ACVR1,DUSP8,PTPN21,NDRG2,CEBPA,SLC2A13,ITPR2,ABAT,PRKCA,CACNB4,HMCN1,EPDR1,EPCAM,FKBP9,PPM1E,PMAIP1,DLX6,MARVELD2,CFHR1,TMEM143,TMEM37,TLN2,OR2W3,TSHR,FANK1,TBC1D8,PNRC1,WISP3,CAPN5,BNIP3L,TTC22,ABCC2,TNS1,PLEKHA1,ACVR2B,SGK2,SAV1,NT5DC2,PLEKHB1,DYRK1B,TCF7L1,PLK2,RASGRF2,ERN1,ALDOA,ARHGAP28,MAPK13,TANC2,APBA2,TMEM63C,RGS16,SCN5A,RUNX2,ZNF395,ZHX3,BVES,UBASH3B,CYP2J2,FBXO4,CYP4V2,SETBP1,RASL11B,ATP6V1E2,CHADL,TNFRSF10C,SATB1,DYNC1I1,FHOD3,NUMBL,RALGPS2,SLC30A4,MYC,ZIC5,EBF4,SRGAP1,GAN,BNIP3,MOXD1,STXBP1,GPR161,IL17RD,QSOX1,SPATA13,PPFIA4,WDR25,WWC1,STRADB,MAFB,PRDM1,OR11H4,ZNF558,ADAMTS3,KIAA0355,LRRIQ3,EMILIN2,HK2,CLMN,IQSEC2,RNF122,SMYD3,RASAL2,DOCK1,ST14,CCDC110,PLXNA2,RHPN2,FAM198B,COLEC10,KIF21B,RADIL,TIAM2,ZNF827,RPS6KL1,DACT1,ZNF521,EEPD1,MAP7,DAB2IP,MYH15,PJA1,PDE4D,RAB27B,DNAH5,FAM78B,HSPA2,DZANK1,PHLDB2,GAPDH,UROS,PDK1,PTPN6,ADCY1,NLGN4X,SATB2,WNT11,RAB38,TBC1D16,JAM3,IQCK,LMLN,P4HA1,TNFSF15,DISP1,COBL,C2orf88,MXI1,NECAB2,PRSS16,ARHGEF11,BIK,BLVRB,KIF5C,ARL2,GAS6,OVOL2,NEO1,RGS17,GPR155,PRKCD,RASD2,TRIM3,SGK1,KIAA0408,SMPDL3A,PARP9,TMC7,MN1,SLC40A1,PXN,MPP1,OGDHL,NUAK2,PALLD,TLR6,RERE,CTIF,GPLD1,TRIB3,FGR,GNAO1,FMO4,MAP2K6,MYOM2,ZNF474,TNFRSF17,RNF157,DDIT3 |
| 1.274e-03 | -6.67 | GO_RHO_GUANYL_NUCLEOTIDE_EXCHANGE_FACTOR_ACTIVITY | MSigDB lists | GO_RHO_GUANYL_NUCLEOTIDE_EXCHANGE_FACTOR_ACTIVITY | 74 | 6 | 17377 | 282 |
ARHGEF11,DOCK1,RASGRF2,TIAM2,PLEKHG1,SPATA13 |
| 1.281e-03 | -6.66 | GTGCCAT,MIR-183 | MSigDB lists | GTGCCAT,MIR-183 | 161 | 9 | 17377 | 282 |
PPM1E,PHLDB2,KLHL3,KIAA0355,BNIP3L,PDE4D,PRKCA,PFN2,NCS1 |
| 1.296e-03 | -6.65 | small_cell_carcinoma | COSMIC cancer mutations | small_cell_carcinoma | 10152 | 189 | 17385 | 281 |
ARHGAP26,ACSL1,ACVR1,DUSP8,PTPN21,NDRG2,CEBPA,SLC2A13,ITPR2,ABAT,PRKCA,CACNB4,HMCN1,EPDR1,EPCAM,FKBP9,PPM1E,PMAIP1,DLX6,MARVELD2,CFHR1,TMEM143,TMEM37,TLN2,OR2W3,TSHR,FANK1,TBC1D8,PNRC1,WISP3,CAPN5,BNIP3L,TTC22,ABCC2,TNS1,PLEKHA1,ACVR2B,SGK2,SAV1,NT5DC2,PLEKHB1,DYRK1B,TCF7L1,PLK2,RASGRF2,ERN1,ALDOA,ARHGAP28,MAPK13,TANC2,APBA2,TMEM63C,RGS16,SCN5A,RUNX2,ZNF395,ZHX3,BVES,UBASH3B,CYP2J2,FBXO4,CYP4V2,SETBP1,RASL11B,ATP6V1E2,CHADL,TNFRSF10C,SATB1,DYNC1I1,FHOD3,NUMBL,RALGPS2,SLC30A4,MYC,ZIC5,EBF4,SRGAP1,GAN,BNIP3,MOXD1,STXBP1,GPR161,IL17RD,QSOX1,SPATA13,PPFIA4,WDR25,WWC1,STRADB,MAFB,PRDM1,OR11H4,ZNF558,ADAMTS3,KIAA0355,LRRIQ3,EMILIN2,HK2,CLMN,IQSEC2,RNF122,SMYD3,RASAL2,DOCK1,ST14,CCDC110,PLXNA2,RHPN2,FAM198B,COLEC10,KIF21B,RADIL,TIAM2,ZNF827,RPS6KL1,DACT1,ZNF521,EEPD1,MAP7,DAB2IP,MYH15,PJA1,PDE4D,RAB27B,DNAH5,FAM78B,HSPA2,DZANK1,PHLDB2,GAPDH,UROS,PDK1,PTPN6,ADCY1,NLGN4X,SATB2,WNT11,RAB38,TBC1D16,JAM3,IQCK,LMLN,P4HA1,TNFSF15,DISP1,COBL,C2orf88,MXI1,NECAB2,PRSS16,ARHGEF11,BIK,BLVRB,KIF5C,ARL2,GAS6,OVOL2,NEO1,RGS17,GPR155,PRKCD,RASD2,TRIM3,SGK1,KIAA0408,SMPDL3A,PARP9,TMC7,MN1,SLC40A1,PXN,MPP1,OGDHL,NUAK2,PALLD,TLR6,RERE,CTIF,GPLD1,TRIB3,FGR,GNAO1,FMO4,MAP2K6,MYOM2,ZNF474,TNFRSF17,RNF157,DDIT3 |
| 1.300e-03 | -6.65 | regulation of stress fiber assembly | biological process | GO:0051492 | 77 | 6 | 17256 | 270 |
ARHGAP28,PHLDB2,WNT11,PPM1E,PXN,PFN2 |
| 1.318e-03 | -6.63 | ovary-carcinoma-mucinous_carcinoma | COSMIC cancer mutations | ovary-carcinoma-mucinous_carcinoma | 458 | 17 | 17385 | 281 |
ACVR1,PDK1,NUAK2,STRADB,ACVR2B,SGK2,PRKCA,DYRK1B,TRIB3,FGR,RPS6KL1,MAP2K6,PLK2,ERN1,PRKCD,SGK1,MAPK13 |
| 1.322e-03 | -6.63 | intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress | biological process | GO:0070059 | 31 | 4 | 17256 | 270 |
TRIB3,DAB2IP,DDIT3,ERN1 |
| 1.322e-03 | -6.63 | positive regulation of organic acid transport | biological process | GO:0032892 | 31 | 4 | 17256 | 270 |
ABAT,KMO,STXBP1,MAP2K6 |
| 1.322e-03 | -6.63 | regulation of platelet activation | biological process | GO:0010543 | 31 | 4 | 17256 | 270 |
ABAT,PRKCA,UBASH3B,PRKCD |
| 1.323e-03 | -6.63 | regulation of catalytic activity | biological process | GO:0050790 | 2299 | 54 | 17256 | 270 |
ARHGAP26,RGS16,ACSL1,DUSP8,RASAL2,ARHGEF11,DOCK1,BVES,RECK,C4A,UBASH3B,PLXNA2,ARL2,CEBPA,GAS6,TNFRSF10C,DYNC1I1,PFN2,TIAM2,PPM1E,RGS17,PMAIP1,MYC,PRKCD,SRGAP1,SGK1,INAVA,DAB2IP,EPHB6,TSHR,HSPA2,PARP9,TBC1D8,GAPDH,PTPN6,ADCY1,EFNA3,STRADB,WNT11,ACVR2B,ARRDC4,TBC1D16,TLR6,GPLD1,TRIB3,FGR,MAP2K6,GNAO1,WWTR1,ERN1,ARHGAP28,TNFSF15,SMYD3,PKIA |
| 1.334e-03 | -6.62 | REACTOME_DAG_AND_IP3_SIGNALING | MSigDB lists | REACTOME_DAG_AND_IP3_SIGNALING | 30 | 4 | 17377 | 282 |
ITPR2,PRKCA,PRKCD,ADCY1 |
| 1.334e-03 | -6.62 | SHIN_B_CELL_LYMPHOMA_CLUSTER_2 | MSigDB lists | SHIN_B_CELL_LYMPHOMA_CLUSTER_2 | 30 | 4 | 17377 | 282 |
PRDM1,MXI1,MYC,PRKCD |
| 1.348e-03 | -6.61 | GO_POSITIVE_REGULATION_OF_NUCLEASE_ACTIVITY | MSigDB lists | GO_POSITIVE_REGULATION_OF_NUCLEASE_ACTIVITY | 14 | 3 | 17377 | 282 |
DAB2IP,PRKCD,ERN1 |
| 1.348e-03 | -6.61 | VANDESLUIS_COMMD1_TARGETS_GROUP_2_UP | MSigDB lists | VANDESLUIS_COMMD1_TARGETS_GROUP_2_UP | 14 | 3 | 17377 | 282 |
BNIP3,PDK1,HK2 |
| 1.355e-03 | -6.60 | parotid | COSMIC cancer mutations | parotid | 584 | 20 | 17385 | 281 |
IL17RD,ACVR1,PDK1,ACVR2B,PRKCA,PALLD,CBLN1,NEO1,ZNF827,TRIB3,FGR,PLK2,RPS6KL1,MAP2K6,HK2,SGK1,MAPK13,OR2W3,DNAH5,DDIT3 |
| 1.356e-03 | -6.60 | positive regulation of catalytic activity | biological process | GO:0043085 | 1413 | 37 | 17256 | 270 |
ARHGAP26,RGS16,ACSL1,RASAL2,ARHGEF11,DOCK1,GAS6,DYNC1I1,PFN2,TIAM2,RGS17,PMAIP1,MYC,PRKCD,SRGAP1,INAVA,DAB2IP,EPHB6,TSHR,HSPA2,TBC1D8,ADCY1,EFNA3,STRADB,WNT11,ACVR2B,ARRDC4,TBC1D16,TLR6,GPLD1,TRIB3,FGR,MAP2K6,GNAO1,ERN1,ARHGAP28,TNFSF15 |
| 1.364e-03 | -6.60 | DAG and IP3 signaling | REACTOME pathways | R-HSA-1489509 | 34 | 4 | 10287 | 148 |
ITPR2,PRKCA,PRKCD,ADCY1 |
| 1.377e-03 | -6.59 | Opioid Signalling | REACTOME pathways | R-HSA-111885 | 85 | 6 | 10287 | 148 |
ITPR2,PDE4D,PRKCA,GNAO1,PRKCD,ADCY1 |
| 1.381e-03 | -6.58 | mucinous_carcinoma | COSMIC cancer mutations | mucinous_carcinoma | 460 | 17 | 17385 | 281 |
ACVR1,PDK1,NUAK2,STRADB,ACVR2B,SGK2,PRKCA,DYRK1B,TRIB3,FGR,RPS6KL1,MAP2K6,PLK2,ERN1,PRKCD,SGK1,MAPK13 |
| 1.382e-03 | -6.58 | PLASARI_TGFB1_TARGETS_10HR_DN | MSigDB lists | PLASARI_TGFB1_TARGETS_10HR_DN | 230 | 11 | 17377 | 282 |
TMEM53,SLC40A1,LGR4,PLEKHG1,ZNF521,BNIP3L,PRICKLE2,ARHGAP28,DBP,HERC6,PARP9 |
| 1.390e-03 | -6.58 | odontogenesis of dentin-containing tooth | biological process | GO:0042475 | 78 | 6 | 17256 | 270 |
ENAM,SCN5A,MSX1,ACVR2B,DLX2,RUNX2 |
| 1.400e-03 | -6.57 | GSE10325_LUPUS_BCELL_VS_LUPUS_MYELOID_DN | MSigDB lists | GSE10325_LUPUS_BCELL_VS_LUPUS_MYELOID_DN | 196 | 10 | 17377 | 282 |
ARHGAP26,QSOX1,HEBP1,MPP1,BLVRB,HK2,KIAA0513,MAFB,CEBPA,TBC1D8 |
| 1.401e-03 | -6.57 | STK33_UP | MSigDB lists | STK33_UP | 266 | 12 | 17377 | 282 |
ACVR1,DUSP8,KMO,GAN,MAFB,SGK1,SETBP1,TNFSF15,FAM198B,NCEH1,GPR137C,TLR6 |
| 1.403e-03 | -6.57 | GO_EPITHELIUM_DEVELOPMENT | MSigDB lists | GO_EPITHELIUM_DEVELOPMENT | 892 | 27 | 17377 | 282 |
B9D1,EPB41L5,SLC40A1,MSX1,ACVR1,LGR4,ST14,KLHL3,SOX21,CAPN5,PLXNA2,WNT11,PRDM1,ACVR2B,OVOL2,SAV1,PALLD,SATB1,EPCAM,DLX6,DACT1,MYC,MARVELD2,ACTA2,PDE4D,BARX1,COBL |
| 1.407e-03 | -6.57 | KLF5 (Kruppel like factor 5) | protein interactions | 688 | 50 | 5 | 17029 | 283 |
CEBPA,PRKCA,PRKCD,WWTR1,GTF2F2 |
| 1.408e-03 | -6.57 | movement of cell or subcellular component | biological process | GO:0006928 | 1416 | 37 | 17256 | 270 |
SCN5A,ACVR1,DOCK1,BVES,PLXNA2,KIF5C,GAS6,OVOL2,KIF21B,PRKCA,DYNC1I1,NEO1,EPCAM,PRKCD,DAB2IP,MYH15,PDE4D,DNAH5,PARP9,EPB41L5,BDNF,PXN,SLC9C1,PTPN6,SPATA13,EFNA3,WWC1,TNS1,WNT11,SATB2,PALLD,JAM3,CENPV,GPLD1,RERE,IFT81,FGR |
| 1.419e-03 | -6.56 | liver-carcinoma | COSMIC cancer mutations | liver-carcinoma | 15799 | 269 | 17385 | 281 |
ARHGAP26,ACVR1,DUSP8,LGR4,RECK,LSM11,ALG1L,CEBPA,PRKCA,ABHD6,NCS1,EPDR1,PMAIP1,CFHR1,TMEM37,TSHR,TBC1D8,KLHL23,KLHL3,WISP3,EXOC6B,DSTN,BNIP3L,SLC25A28,ABCC2,TNS1,ACVR2B,SAV1,SPATA9,PLK2,RASGRF2,ALDOA,ARHGAP28,MAPK13,TMOD2,TANC2,SCN5A,TMEM63C,ZHX3,CYP2J2,SLC36A4,TNFRSF10C,DYNC1I1,HPCAL4,NIPSNAP3B,MTUS1,IL17D,RALGPS2,MYC,ZIC5,SRGAP1,MOXD1,STXBP1,GPR161,EPB41L5,BDNF,QSOX1,SHISA2,ARRDC4,OR11H4,ZNF558,ADAMTS3,ISM1,LRRIQ3,QPCTL,EMILIN2,CLMN,IQSEC2,SMYD3,ZNF516,RASAL2,ST14,FAM131C,CCDC110,PLXNA2,COLEC10,TIAM2,TMEM53,ZNF827,KMO,DACT1,DAB2IP,PJA1,PDE4D,RAB27B,DNAH5,ATP6AP1L,C3orf67,DZANK1,GAPDH,PDK1,SOX21,CYB5R2,SFXN4,ADCY1,NLGN4X,SATB2,WNT11,RAB38,TBC1D16,TRIQK,IQCK,WFS1,WWTR1,PLEKHG1,P4HA1,TNFSF15,DBP,KLHL31,COBL,KCTD1,CCDC148,MXI1,TMEM132C,BACE1,BIK,CCNJL,KIF5C,ARL2,ZNF219,NEO1,RGS17,GPR155,SMPDL3A,PARP9,TMC7,MN1,B9D1,SLC40A1,PXN,MPP1,GPR137C,GPLD1,TRIB3,FGR,GNAO1,MYOM2,TNFRSF17,DDIT3,B4GALT7,PHC1,CCDC126,ACSL1,HEBP1,PTPN21,NDRG2,NRN1,ABAT,ITPR2,SLC2A13,CACNB4,ABHD4,HMCN1,EPCAM,PPM1E,FKBP9,CPNE2,MARVELD2,DLX6,TMEM143,TLN2,FANK1,OR2W3,PGBD5,PNRC1,CAPN5,TTC22,PLEKHA1,SGK2,NT5DC2,PLEKHB1,DYRK1B,SPNS1,TCF7L1,ERN1,DLX2,APBA2,GPR63,LONRF1,RGS16,RUNX2,ZNF395,BVES,SCART1,FBXO4,UBASH3B,CYP4V2,RASL11B,SETBP1,CHADL,SATB1,FHOD3,NUMBL,SLC30A4,GAN,EBF4,BNIP3,NCEH1,VGLL4,BARX1,IL17RD,SPATA13,EFNA3,STRADB,WWC1,WDR25,PPFIA4,LHPP,PRDM1,B4GALNT3,KIAA0355,HK2,RNF122,DOCK1,RHPN2,FAM198B,KIF21B,RADIL,KCTD15,RPS6KL1,ZDHHC23,EEPD1,ZNF521,MAP7,MYH15,TMEM120B,HSPA2,FAM78B,PHLDB2,UROS,PTPN6,SLC39A8,JAM3,CENPV,IFT81,LMLN,ANKRD31,RBPMS2,DISP1,NECAB2,PRSS16,ARHGEF11,BLVRB,OVOL2,PRKCD,RASD2,EHD3,GTF2F2,ACTA2,PRICKLE2,TRIM3,SGK1,CCDC122,KIAA0408,MSX1,NUAK2,OGDHL,EXOG,PALLD,TLR6,CTIF,RERE,FMO4,MAP2K6,KIAA0513,ZNF474,THAP10,RNF157,PKIA |
| 1.433e-03 | -6.55 | regulation of determination of dorsal identity | biological process | GO:2000015 | 4 | 2 | 17256 | 270 |
ACVR1,DDIT3 |
| 1.433e-03 | -6.55 | renal sodium ion absorption | biological process | GO:0070294 | 4 | 2 | 17256 | 270 |
SGK1,KLHL3 |
| 1.433e-03 | -6.55 | hematopoietic stem cell migration | biological process | GO:0035701 | 4 | 2 | 17256 | 270 |
GAS6,GPLD1 |
| 1.443e-03 | -6.54 | RGS7 (regulator of G protein signaling 7) | protein interactions | 6000 | 14 | 3 | 17029 | 283 |
MSX1,PRKCA,GNAO1 |
| 1.444e-03 | -6.54 | GO_CELL_MORPHOGENESIS_INVOLVED_IN_DIFFERENTIATION | MSigDB lists | GO_CELL_MORPHOGENESIS_INVOLVED_IN_DIFFERENTIATION | 501 | 18 | 17377 | 282 |
EPB41L5,BDNF,MSX1,ST14,BVES,PTPN6,ADCY1,PLXNA2,EFNA3,KIF5C,WNT11,PALLD,RADIL,NEO1,RERE,NUMBL,STXBP1,COBL |
| 1.448e-03 | -6.54 | GO_CELL_DEVELOPMENT | MSigDB lists | GO_CELL_DEVELOPMENT | 1366 | 37 | 17377 | 282 |
ACVR1,RUNX2,ST14,BVES,PLXNA2,KIF5C,CEBPA,OVOL2,CACNB4,RADIL,FHOD3,NEO1,NUMBL,MARVELD2,ACTA2,SGK1,DAB2IP,PDE4D,STXBP1,HSPA2,EPB41L5,BDNF,MSX1,PTPN6,EFNA3,ADCY1,WNT11,SATB2,PRDM1,PALLD,JAM3,RERE,GNAO1,CLMN,TMOD2,SMYD3,COBL |
| 1.454e-03 | -6.53 | GTATTAT,MIR-369-3P | MSigDB lists | GTATTAT,MIR-369-3P | 197 | 10 | 17377 | 282 |
NUMBL,ZNF395,PNRC1,ADAMTS3,KLHL3,BACE1,ARHGAP28,PDE4D,PRKCA,PKIA |
| 1.454e-03 | -6.53 | HALLMARK_GLYCOLYSIS | MSigDB lists | HALLMARK_GLYCOLYSIS | 197 | 10 | 17377 | 282 |
QSOX1,MXI1,ALDOA,CAPN5,BIK,HK2,EFNA3,P4HA1,LHPP,B4GALT7 |
| 1.457e-03 | -6.53 | MOHANKUMAR_TLX1_TARGETS_DN | MSigDB lists | MOHANKUMAR_TLX1_TARGETS_DN | 164 | 9 | 17377 | 282 |
PHLDB2,BIK,MAFB,SGK1,KIF5C,MAPK13,FAM198B,PKIA,DDIT3 |
| 1.463e-03 | -6.53 | REACTOME_OPIOID_SIGNALLING | MSigDB lists | REACTOME_OPIOID_SIGNALLING | 76 | 6 | 17377 | 282 |
ITPR2,PDE4D,PRKCA,GNAO1,PRKCD,ADCY1 |
| 1.529e-03 | -6.48 | central_nervous_system-brainstem-glioma-astrocytoma | COSMIC cancer mutations | central_nervous_system-brainstem-glioma-astrocytoma | 4 | 2 | 17385 | 281 |
ACVR1,KIAA1549 |
| 1.536e-03 | -6.48 | regulation of protein phosphorylation | biological process | GO:0001932 | 1423 | 37 | 17256 | 270 |
ACSL1,ACVR1,NECAB2,DUSP8,UBASH3B,NDRG2,CEBPA,GAS6,TNFRSF10C,PRKCA,PFN2,PPM1E,DACT1,MYC,PRKCD,INAVA,DAB2IP,PDE4D,EPHB6,HSPA2,PARP9,PTPN6,ADCY1,WWC1,STRADB,WNT11,GAREM1,ACVR2B,TLR6,TRIB3,FGR,MAP2K6,WWTR1,ERN1,TNFSF15,SMYD3,PKIA |
| 1.557e-03 | -6.47 | central_nervous_system-brain-primitive_neuroectodermal_tumour-medulloblastoma-large_cell | COSMIC cancer mutations | central_nervous_system-brain-primitive_neuroectodermal_tumour-medulloblastoma-large_cell | 1136 | 32 | 17385 | 281 |
ARHGAP26,MXI1,NECAB2,DOCK1,CCDC110,CCNJL,ARL2,HMCN1,FHOD3,MTUS1,EEPD1,GTF2F2,MOXD1,TLN2,DNAH5,TMEM120B,FANK1,DZANK1,TMC7,BDNF,KLHL3,DSTN,WNT11,PALLD,JAM3,TRIB3,LMLN,PLEKHG1,MYOM2,APBA2,SMYD3,COBL |
| 1.567e-03 | -6.46 | regulation of GTPase activity | biological process | GO:0043087 | 481 | 17 | 17256 | 270 |
ARHGAP26,RGS16,RASAL2,ARHGEF11,DOCK1,BVES,PLXNA2,ARL2,WNT11,TBC1D16,TIAM2,RGS17,GNAO1,SRGAP1,ARHGAP28,DAB2IP,TBC1D8 |
| 1.589e-03 | -6.44 | GO_REGULATION_OF_SMALL_GTPASE_MEDIATED_SIGNAL_TRANSDUCTION | MSigDB lists | GO_REGULATION_OF_SMALL_GTPASE_MEDIATED_SIGNAL_TRANSDUCTION | 270 | 12 | 17377 | 282 |
ARHGAP26,RASAL2,RALGPS2,ARHGEF11,RASGRF2,SPATA13,PLEKHG1,SRGAP1,ARHGAP28,DAB2IP,IQSEC2,TIAM2 |
| 1.599e-03 | -6.44 | CREIGHTON_ENDOCRINE_THERAPY_RESISTANCE_5 | MSigDB lists | CREIGHTON_ENDOCRINE_THERAPY_RESISTANCE_5 | 424 | 16 | 17377 | 282 |
PHLDB2,ACSL1,BIK,RASL11B,FAM198B,NIPSNAP3B,MTUS1,TRIB3,ZNF827,PLK2,ZDHHC23,PRICKLE2,RAB27B,NCEH1,SMYD3,HSPA2 |
| 1.607e-03 | -6.43 | upper_aerodigestive_tract-mouth-carcinoma-adenoid_cystic_carcinoma | COSMIC cancer mutations | upper_aerodigestive_tract-mouth-carcinoma-adenoid_cystic_carcinoma | 386 | 15 | 17385 | 281 |
TRIB3,FGR,ACVR1,PDK1,PLK2,MAP2K6,RPS6KL1,HK2,SGK1,MAPK13,ACVR2B,PRKCA,PALLD,DDIT3,NEO1 |
| 1.607e-03 | -6.43 | salivary_gland-carcinoma | COSMIC cancer mutations | salivary_gland-carcinoma | 386 | 15 | 17385 | 281 |
TRIB3,FGR,ACVR1,PDK1,PLK2,MAP2K6,RPS6KL1,HK2,SGK1,MAPK13,ACVR2B,PRKCA,PALLD,DDIT3,NEO1 |
| 1.607e-03 | -6.43 | upper_aerodigestive_tract-head_neck-carcinoma-adenoid_cystic_carcinoma | COSMIC cancer mutations | upper_aerodigestive_tract-head_neck-carcinoma-adenoid_cystic_carcinoma | 386 | 15 | 17385 | 281 |
TRIB3,FGR,ACVR1,PDK1,PLK2,MAP2K6,RPS6KL1,HK2,SGK1,MAPK13,ACVR2B,PRKCA,PALLD,DDIT3,NEO1 |
| 1.607e-03 | -6.43 | upper_aerodigestive_tract-lymph_node-carcinoma-adenoid_cystic_carcinoma | COSMIC cancer mutations | upper_aerodigestive_tract-lymph_node-carcinoma-adenoid_cystic_carcinoma | 386 | 15 | 17385 | 281 |
TRIB3,FGR,ACVR1,PDK1,PLK2,MAP2K6,RPS6KL1,HK2,SGK1,MAPK13,ACVR2B,PRKCA,PALLD,DDIT3,NEO1 |
| 1.607e-03 | -6.43 | upper_aerodigestive_tract-carcinoma | COSMIC cancer mutations | upper_aerodigestive_tract-carcinoma | 386 | 15 | 17385 | 281 |
TRIB3,FGR,ACVR1,PDK1,PLK2,MAP2K6,RPS6KL1,HK2,SGK1,MAPK13,ACVR2B,PRKCA,PALLD,DDIT3,NEO1 |
| 1.615e-03 | -6.43 | FFAR2 (free fatty acid receptor 2) | protein interactions | 2867 | 4 | 2 | 17029 | 283 |
GNAO1,CYB5R2 |
| 1.615e-03 | -6.43 | ANKRD36 (ankyrin repeat domain 36) | protein interactions | 375248 | 4 | 2 | 17029 | 283 |
GAPDH,GAN |
| 1.618e-03 | -6.43 | LABBE_WNT3A_TARGETS_UP | MSigDB lists | LABBE_WNT3A_TARGETS_UP | 105 | 7 | 17377 | 282 |
SGK1,DUSP8,SGK2,STXBP1,PTPN6,PTPN21,GPLD1 |
| 1.630e-03 | -6.42 | transition metal ion transport | biological process | GO:0000041 | 109 | 7 | 17256 | 270 |
ATP6V1E2,SLC40A1,SLC25A28,ABCC2,SLC30A4,SLC39A8,ATOX1 |
| 1.633e-03 | -6.42 | KRAS.KIDNEY_UP.V1_UP | MSigDB lists | KRAS.KIDNEY_UP.V1_UP | 135 | 8 | 17377 | 282 |
ADCY1,MAFB,KIF5C,MAP7,NRN1,DYNC1I1,SATB1,HPCAL4 |
| 1.650e-03 | -6.41 | GO_NEGATIVE_REGULATION_OF_PROTEIN_POLYMERIZATION | MSigDB lists | GO_NEGATIVE_REGULATION_OF_PROTEIN_POLYMERIZATION | 53 | 5 | 17377 | 282 |
SGK1,TMOD2,PFN2,PRKCD,FHOD3 |
| 1.651e-03 | -6.41 | GSE21670_IL6_VS_TGFB_AND_IL6_TREATED_CD4_TCELL_UP | MSigDB lists | GSE21670_IL6_VS_TGFB_AND_IL6_TREATED_CD4_TCELL_UP | 167 | 9 | 17377 | 282 |
ARHGEF11,HEBP1,RASGRF2,UBASH3B,NUAK2,TMEM37,PRKCA,APBA2,PFN2 |
| 1.651e-03 | -6.41 | GSE20484_MCSG_VS_CXCL4_MONOCYTE_DERIVED_MACROPHAGE_UP | MSigDB lists | GSE20484_MCSG_VS_CXCL4_MONOCYTE_DERIVED_MACROPHAGE_UP | 167 | 9 | 17377 | 282 |
SPNS1,SCN5A,FGR,CYB5R2,MYC,CLMN,SLC36A4,ZNF219,PHC1 |
| 1.665e-03 | -6.40 | RODRIGUES_NTN1_TARGETS_UP | MSigDB lists | RODRIGUES_NTN1_TARGETS_UP | 15 | 3 | 17377 | 282 |
BDNF,SATB2,FHOD3 |
| 1.665e-03 | -6.40 | GO_LONG_TERM_SYNAPTIC_DEPRESSION | MSigDB lists | GO_LONG_TERM_SYNAPTIC_DEPRESSION | 15 | 3 | 17377 | 282 |
STXBP1,ABHD6,PLK2 |
| 1.668e-03 | -6.40 | signaling | biological process | GO:0023052 | 5365 | 107 | 17256 | 270 |
ARHGAP26,ACSL1,ZNF516,ACVR1,LGR4,RASAL2,DOCK1,HEBP1,PLXNA2,RHPN2,NDRG2,CEBPA,ITPR2,PRKCA,CACNB4,RADIL,CBLN1,TIAM2,NCS1,EPCAM,PMAIP1,DACT1,RPS6KL1,DAB2IP,PDE4D,EPHB6,RAB27B,OR2W3,TSHR,PDK1,WISP3,PTPN6,CAPN5,BNIP3L,ADCY1,WNT11,ACVR2B,RAB38,PLEKHA1,SGK2,SAV1,JAM3,GRK3,PLEKHB1,SPNS1,TCF7L1,RASGRF2,PLK2,WFS1,ERN1,WWTR1,ARHGAP28,TNFSF15,MAPK13,TMOD2,DISP1,APBA2,GPR63,SCN5A,RGS16,RUNX2,ARHGEF11,UBASH3B,ATP6V1E2,RASL11B,GAS6,TNFRSF10C,ZNF219,HPCAL4,NEO1,NUMBL,RALGPS2,GPR155,MYC,PRKCD,RASD2,GTF2F2,SRGAP1,SGK1,PRICKLE2,INAVA,BNIP3,STXBP1,BARX1,GPR161,B9D1,IL17RD,BDNF,PXN,MSX1,MPP1,NUAK2,EFNA3,PPFIA4,WWC1,STRADB,GAREM1,ARRDC4,OR11H4,TLR6,GPLD1,TRIB3,FGR,MAP2K6,GNAO1,TNFRSF17,DDIT3 |
| 1.678e-03 | -6.39 | negative regulation of fibroblast proliferation | biological process | GO:0048147 | 33 | 4 | 17256 | 270 |
DAB2IP,FBXO4,MYC,B4GALT7 |
| 1.689e-03 | -6.38 | SHEPARD_BMYB_MORPHOLINO_UP | MSigDB lists | SHEPARD_BMYB_MORPHOLINO_UP | 201 | 10 | 17377 | 282 |
C4A,MPP1,BNIP3L,RASL11B,WNT11,SLC25A28,ABAT,EXOG,HSPA2,EPDR1 |
| 1.689e-03 | -6.38 | MCBRYAN_PUBERTAL_BREAST_3_4WK_UP | MSigDB lists | MCBRYAN_PUBERTAL_BREAST_3_4WK_UP | 201 | 10 | 17377 | 282 |
EPCAM,PDK1,ST14,SLC39A8,PLK2,MAFB,WWC1,DBP,RAB27B,EPDR1 |
| 1.694e-03 | -6.38 | PLC-gamma1 signalling | REACTOME pathways | R-HSA-167021 | 36 | 4 | 10287 | 148 |
ITPR2,PRKCA,PRKCD,ADCY1 |
| 1.694e-03 | -6.38 | EGFR interacts with phospholipase C-gamma | REACTOME pathways | R-HSA-212718 | 36 | 4 | 10287 | 148 |
ITPR2,PRKCA,PRKCD,ADCY1 |
| 1.709e-03 | -6.37 | GGGCATT,MIR-365 | MSigDB lists | GGGCATT,MIR-365 | 106 | 7 | 17377 | 282 |
SGK1,SATB2,PRDM1,ACVR1,VGLL4,TIAM2,SRGAP1 |
| 1.717e-03 | -6.37 | lung-carcinoid-endocrine_tumour-atypical | COSMIC cancer mutations | lung-carcinoid-endocrine_tumour-atypical | 511 | 18 | 17385 | 281 |
ACVR1,RASAL2,PDK1,NUAK2,STRADB,ACVR2B,SGK2,PRKCA,DYRK1B,TRIB3,FGR,RPS6KL1,MAP2K6,PLK2,PRKCD,ERN1,SGK1,MAPK13 |
| 1.721e-03 | -6.37 | GSE32986_UNSTIM_VS_GMCSF_STIM_DC_UP | MSigDB lists | GSE32986_UNSTIM_VS_GMCSF_STIM_DC_UP | 168 | 9 | 17377 | 282 |
PDK1,RALGPS2,PNRC1,RECK,NDRG2,ABCC2,APBA2,PFN2,CENPV |
| 1.738e-03 | -6.36 | Rho guanyl-nucleotide exchange factor activity | molecular function | GO:0005089 | 79 | 6 | 17224 | 278 |
ARHGEF11,DOCK1,RASGRF2,TIAM2,PLEKHG1,SPATA13 |
| 1.771e-03 | -6.34 | MEISSNER_NPC_HCP_WITH_H3K4ME2 | MSigDB lists | MEISSNER_NPC_HCP_WITH_H3K4ME2 | 469 | 17 | 17377 | 282 |
MN1,C2orf88,NECAB2,GAS6,DYNC1I1,RADIL,EPCAM,KCTD15,EMILIN2,ZDHHC23,MAP7,CCDC122,ARHGAP28,PRICKLE2,BARX1,SMPDL3A,C3orf67 |
| 1.782e-03 | -6.33 | WWC2 (WW and C2 domain containing 2) | protein interactions | 80014 | 15 | 3 | 17029 | 283 |
WWC1,PRKCA,PTPN21 |
| 1.784e-03 | -6.33 | negative regulation of signal transduction | biological process | GO:0009968 | 1284 | 34 | 17256 | 270 |
RGS16,RUNX2,ACVR1,DUSP8,LGR4,RASAL2,UBASH3B,RASL11B,NDRG2,GAS6,CBLN1,RGS17,DACT1,MYC,PRKCD,DAB2IP,EPHB6,BARX1,GPR161,PTPN6,WWC1,STRADB,NLGN4X,SHISA2,WNT11,PRDM1,PLEKHA1,TLR6,TRIB3,RBPMS2,WFS1,WWTR1,DLX2,DDIT3 |
| 1.793e-03 | -6.32 | GCM_PTK2 | MSigDB lists | GCM_PTK2 | 137 | 8 | 17377 | 282 |
ARHGAP26,BACE1,KIF5C,TMOD2,PLEKHA1,ABHD6,PLEKHB1,NCS1 |
| 1.793e-03 | -6.32 | Ca2+ pathway | REACTOME pathways | R-HSA-4086398 | 61 | 5 | 10287 | 148 |
TCF7L1,WNT11,ITPR2,PRKCA,GNAO1 |
| 1.824e-03 | -6.31 | long term synaptic depression | biological process | GO:0060292 | 16 | 3 | 17256 | 270 |
ABHD6,STXBP1,PLK2 |
| 1.824e-03 | -6.31 | positive regulation of nuclease activity | biological process | GO:0032075 | 16 | 3 | 17256 | 270 |
DAB2IP,PRKCD,ERN1 |
| 1.830e-03 | -6.30 | PLD2 (phospholipase D2) | protein interactions | 5338 | 53 | 5 | 17029 | 283 |
GAPDH,PRKCA,STXBP1,ALDOA,PRKCD |
| 1.837e-03 | -6.30 | AGC-kinase_C | interpro domains | IPR000961 | 55 | 5 | 18492 | 296 |
SGK1,SGK2,PRKCA,GRK3,PRKCD |
| 1.844e-03 | -6.30 | S_TK_X | smart domains | SM00133 | 49 | 5 | 9493 | 172 |
SGK1,SGK2,PRKCA,GRK3,PRKCD |
| 1.845e-03 | -6.30 | Hippo signaling | KEGG pathways | hsa_M00683 | 16 | 3 | 7161 | 113 |
WWC1,SAV1,WWTR1 |
| 1.845e-03 | -6.30 | Hippo signaling | KEGG pathways | M00683 | 16 | 3 | 7161 | 113 |
WWC1,SAV1,WWTR1 |
| 1.887e-03 | -6.27 | HELLER_HDAC_TARGETS_SILENCED_BY_METHYLATION_UP | MSigDB lists | HELLER_HDAC_TARGETS_SILENCED_BY_METHYLATION_UP | 431 | 16 | 17377 | 282 |
DZANK1,MSX1,BIK,OGDHL,MAFB,KIF5C,ABAT,PFN2,PPM1E,PLK2,TMEM143,KIAA0513,DLX2,TLN2,HSPA2,PGBD5 |
| 1.893e-03 | -6.27 | RODRIGUES_THYROID_CARCINOMA_ANAPLASTIC_DN | MSigDB lists | RODRIGUES_THYROID_CARCINOMA_ANAPLASTIC_DN | 472 | 17 | 17377 | 282 |
B9D1,RASAL2,CYP4V2,TNS1,ABAT,NIPSNAP3B,NEO1,MTUS1,RERE,IL17D,IQCK,IGIP,WFS1,SGK1,ACTA2,VGLL4,PKIA |
| 1.897e-03 | -6.27 | central_nervous_system-brain-primitive_neuroectodermal_tumour-medulloblastoma | COSMIC cancer mutations | central_nervous_system-brain-primitive_neuroectodermal_tumour-medulloblastoma | 7398 | 144 | 17385 | 281 |
ARHGAP26,CCDC126,ACSL1,DUSP8,LGR4,RECK,HEBP1,PTPN21,SLC2A13,ITPR2,ABAT,PRKCA,ABHD6,HMCN1,EPDR1,CPNE2,PPM1E,DLX6,MARVELD2,CFHR1,TMEM143,TLN2,TSHR,FANK1,PGBD5,KLHL3,WISP3,CAPN5,ABCC2,TNS1,SGK2,SAV1,DYRK1B,TCF7L1,RASGRF2,ARHGAP28,MAPK13,TMOD2,TANC2,APBA2,LONRF1,TMEM63C,SCN5A,UBASH3B,FBXO4,SETBP1,SLC36A4,TNFRSF10C,SATB1,DYNC1I1,FHOD3,MTUS1,RALGPS2,SRGAP1,GAN,BNIP3,NCEH1,MOXD1,VGLL4,STXBP1,BDNF,EFNA3,SPATA13,WDR25,WWC1,SHISA2,LHPP,B4GALNT3,ADAMTS3,KIAA0355,LRRIQ3,EMILIN2,HK2,CLMN,IQSEC2,RNF122,ZNF516,RASAL2,ST14,DOCK1,PLXNA2,RHPN2,KIF21B,COLEC10,RADIL,TIAM2,ZNF827,TMEM53,EEPD1,ZNF521,MAP7,MYH15,PDE4D,RAB27B,DNAH5,TMEM120B,FAM78B,ATP6AP1L,C3orf67,PHLDB2,GAPDH,SLC39A8,SFXN4,ADCY1,NLGN4X,SATB2,RAB38,TBC1D16,JAM3,IQCK,LMLN,RBPMS2,WFS1,WWTR1,PLEKHG1,DISP1,COBL,CCDC148,TMEM132C,MXI1,ARHGEF11,BLVRB,CCNJL,OVOL2,NEO1,RGS17,GPR155,GTF2F2,PRICKLE2,SGK1,SMPDL3A,MN1,TMC7,MPP1,OGDHL,EXOG,PALLD,CTIF,RERE,FMO4,GNAO1,MAP2K6,MYOM2,RNF157 |
| 1.937e-03 | -6.25 | cell migration | biological process | GO:0016477 | 852 | 25 | 17256 | 270 |
EPB41L5,PXN,ACVR1,DOCK1,BVES,PTPN6,SPATA13,PLXNA2,WWC1,SATB2,WNT11,TNS1,GAS6,OVOL2,PALLD,JAM3,CENPV,RERE,GPLD1,EPCAM,FGR,PRKCD,DAB2IP,PDE4D,PARP9 |
| 1.948e-03 | -6.24 | GO_APOPTOTIC_MITOCHONDRIAL_CHANGES | MSigDB lists | GO_APOPTOTIC_MITOCHONDRIAL_CHANGES | 55 | 5 | 17377 | 282 |
BNIP3,PMAIP1,BIK,HK2,BNIP3L |
| 1.949e-03 | -6.24 | soft_tissue | COSMIC cancer mutations | soft_tissue | 5964 | 120 | 17385 | 281 |
ARHGAP26,ACSL1,ZNF516,LGR4,RASAL2,DOCK1,RECK,FAM131C,PLXNA2,RHPN2,CEBPA,SLC2A13,ITPR2,COLEC10,CACNB4,RADIL,HMCN1,TIAM2,EPDR1,ZNF827,PPM1E,KMO,ZNF521,TMEM143,EEPD1,MAP7,MYH15,PJA1,TLN2,DNAH5,TSHR,FANK1,KIAA1549,TBC1D8,C3orf67,GAPDH,PNRC1,KLHL23,SLC39A8,PTPN6,CAPN5,ADCY1,NLGN4X,SATB2,WNT11,TNS1,ABCC2,PLEKHA1,TRIQK,TBC1D16,CENPV,DYRK1B,TCF7L1,PLK2,WFS1,RASGRF2,ERN1,PLEKHG1,MAPK13,DISP1,KLHL31,TANC2,APBA2,COBL,TMEM63C,SCN5A,CCDC148,TMEM132C,SCART1,ZHX3,ARHGEF11,UBASH3B,CYP2J2,CYP4V2,SETBP1,ARL2,SLC36A4,PFN2,DYNC1I1,FHOD3,NEO1,MTUS1,NUMBL,RALGPS2,SLC30A4,GPR155,MYC,ZIC5,EBF4,GAN,SRGAP1,PRICKLE2,SGK1,KIAA0408,MOXD1,VGLL4,STXBP1,PARP9,EPB41L5,MN1,IL17RD,EFNA3,OGDHL,SPATA13,WWC1,PRDM1,PALLD,B4GALNT3,GPR137C,RERE,ADAMTS3,GNAO1,FMO4,LRRIQ3,EMILIN2,HK2,MYOM2,ZNF474,TNFRSF17,PHC1 |
| 1.991e-03 | -6.22 | atypical | COSMIC cancer mutations | atypical | 518 | 18 | 17385 | 281 |
ACVR1,PDK1,RASAL2,NUAK2,STRADB,ACVR2B,SGK2,PRKCA,DYRK1B,TRIB3,FGR,MAP2K6,RPS6KL1,PLK2,ERN1,PRKCD,SGK1,MAPK13 |
| 2.005e-03 | -6.21 | SMIRNOV_RESPONSE_TO_IR_6HR_DN | MSigDB lists | SMIRNOV_RESPONSE_TO_IR_6HR_DN | 109 | 7 | 17377 | 282 |
P4HA1,BNIP3,PDK1,ZNF395,VGLL4,MYC,HK2 |
| 2.008e-03 | -6.21 | Kinase-like_dom_sf | interpro domains | IPR011009 | 523 | 18 | 18492 | 296 |
ACVR1,NUAK2,STRADB,ACVR2B,SGK2,PRKCA,GRK3,DYRK1B,TRIB3,FGR,MAP2K6,PLK2,RPS6KL1,PRKCD,ERN1,SGK1,MAPK13,EPHB6 |
| 2.021e-03 | -6.20 | V$FOXJ2_01 | MSigDB lists | V$FOXJ2_01 | 172 | 9 | 17377 | 282 |
KCTD15,RUNX2,SCAMP1,SLC39A8,GNAO1,PRDM1,HMCN1,PKIA,NEO1 |
| 2.025e-03 | -6.20 | NIELSEN_SCHWANNOMA_UP | MSigDB lists | NIELSEN_SCHWANNOMA_UP | 16 | 3 | 17377 | 282 |
NLGN4X,ST14,PLEKHB1 |
| 2.031e-03 | -6.20 | GCM_MAPK10 | MSigDB lists | GCM_MAPK10 | 81 | 6 | 17377 | 282 |
IL17D,NDRG2,TMOD2,PLEKHA1,NCS1,PLEKHB1 |
| 2.062e-03 | -6.18 | plasma membrane bounded cell projection part | cellular component | GO:0120038 | 1369 | 35 | 18223 | 280 |
NECAB2,BVES,C4A,BLVRB,KIF5C,NDRG2,KIF21B,PFN2,TIAM2,NCS1,EHD3,TRIM3,DAB2IP,BNIP3,DNAH5,GPR161,EPB41L5,B9D1,BDNF,SPATA13,WWC1,NLGN4X,ABCC2,CATSPERE,PLEKHA1,PALLD,OR11H4,IFT81,FGR,GNAO1,WFS1,PLK2,TMOD2,APBA2,COBL |
| 2.062e-03 | -6.18 | cell projection part | cellular component | GO:0044463 | 1369 | 35 | 18223 | 280 |
NECAB2,BVES,C4A,BLVRB,KIF5C,NDRG2,KIF21B,PFN2,TIAM2,NCS1,EHD3,TRIM3,DAB2IP,BNIP3,DNAH5,GPR161,EPB41L5,B9D1,BDNF,SPATA13,WWC1,NLGN4X,ABCC2,CATSPERE,PLEKHA1,PALLD,OR11H4,IFT81,FGR,GNAO1,WFS1,PLK2,TMOD2,APBA2,COBL |
| 2.103e-03 | -6.16 | LEE_LIVER_CANCER_SURVIVAL_UP | MSigDB lists | LEE_LIVER_CANCER_SURVIVAL_UP | 173 | 9 | 17377 | 282 |
ACSL1,NECAB2,CYP2J2,OGDHL,NDRG2,ABCC2,WNT11,ITPR2,ABHD6 |
| 2.111e-03 | -6.16 | TATCTGG,MIR-488 | MSigDB lists | TATCTGG,MIR-488 | 56 | 5 | 17377 | 282 |
SATB2,CEBPA,PDE4D,VGLL4,PFN2 |
| 2.111e-03 | -6.16 | AMIT_SERUM_RESPONSE_60_MCF10A | MSigDB lists | AMIT_SERUM_RESPONSE_60_MCF10A | 56 | 5 | 17377 | 282 |
SGK1,MAFB,PNRC1,PMAIP1,PLK2 |
| 2.112e-03 | -6.16 | LI_INDUCED_T_TO_NATURAL_KILLER_DN | MSigDB lists | LI_INDUCED_T_TO_NATURAL_KILLER_DN | 110 | 7 | 17377 | 282 |
ACTA2,ACVR2B,ITPR2,PDK1,SATB1,RPS6KL1,PRKCD |
| 2.114e-03 | -6.16 | MODULE_69 | MSigDB lists | MODULE_69 | 477 | 17 | 17377 | 282 |
MSX1,ACVR1,SOX21,NDRG2,WDR25,LHPP,PRDM1,SAV1,SATB1,RERE,SPNS1,RALGPS2,ALDOA,PLEKHG1,PDE4D,TNFRSF17,PKIA |
| 2.134e-03 | -6.15 | GO_NEGATIVE_REGULATION_OF_KINASE_ACTIVITY | MSigDB lists | GO_NEGATIVE_REGULATION_OF_KINASE_ACTIVITY | 243 | 11 | 17377 | 282 |
TRIB3,PPM1E,DUSP8,UBASH3B,PTPN6,PRKCD,WWTR1,DAB2IP,CEBPA,SMYD3,PKIA |
| 2.162e-03 | -6.14 | BOYLAN_MULTIPLE_MYELOMA_D_UP | MSigDB lists | BOYLAN_MULTIPLE_MYELOMA_D_UP | 82 | 6 | 17377 | 282 |
CLMN,TLN2,PLK2,MYC,BLVRB,DDIT3 |
| 2.174e-03 | -6.13 | PEDERSEN_METASTASIS_BY_ERBB2_ISOFORM_7 | MSigDB lists | PEDERSEN_METASTASIS_BY_ERBB2_ISOFORM_7 | 357 | 14 | 17377 | 282 |
PHLDB2,RGS16,PXN,LGR4,PMAIP1,CYP2J2,FBXO4,WWTR1,HK2,PRKCA,SMYD3,PKIA,CENPV,MTUS1 |
| 2.180e-03 | -6.13 | lung-carcinoma-bronchioloalveolar_adenocarcinoma | COSMIC cancer mutations | lung-carcinoma-bronchioloalveolar_adenocarcinoma | 786 | 24 | 17385 | 281 |
ACVR1,PDK1,NUAK2,ADCY1,STRADB,SATB2,CEBPA,ACVR2B,SGK2,PRKCA,JAM3,GPLD1,CTIF,DYRK1B,TRIB3,FGR,PLK2,RPS6KL1,MAP2K6,PRKCD,ERN1,SGK1,MAPK13,APBA2 |
| 2.180e-03 | -6.13 | bronchioloalveolar_adenocarcinoma | COSMIC cancer mutations | bronchioloalveolar_adenocarcinoma | 786 | 24 | 17385 | 281 |
ACVR1,PDK1,NUAK2,ADCY1,STRADB,SATB2,CEBPA,ACVR2B,SGK2,PRKCA,JAM3,GPLD1,CTIF,DYRK1B,TRIB3,FGR,PLK2,RPS6KL1,MAP2K6,PRKCD,ERN1,SGK1,MAPK13,APBA2 |
| 2.180e-03 | -6.13 | localization of cell | biological process | GO:0051674 | 955 | 27 | 17256 | 270 |
EPB41L5,PXN,ACVR1,SLC9C1,DOCK1,BVES,PTPN6,SPATA13,PLXNA2,WWC1,SATB2,WNT11,TNS1,GAS6,OVOL2,PALLD,JAM3,CENPV,RERE,GPLD1,EPCAM,FGR,PRKCD,DAB2IP,PDE4D,DNAH5,PARP9 |
| 2.180e-03 | -6.13 | cell motility | biological process | GO:0048870 | 955 | 27 | 17256 | 270 |
EPB41L5,PXN,ACVR1,SLC9C1,DOCK1,BVES,PTPN6,SPATA13,PLXNA2,WWC1,SATB2,WNT11,TNS1,GAS6,OVOL2,PALLD,JAM3,CENPV,RERE,GPLD1,EPCAM,FGR,PRKCD,DAB2IP,PDE4D,DNAH5,PARP9 |
| 2.190e-03 | -6.12 | positive regulation of amino acid transport | biological process | GO:0051957 | 17 | 3 | 17256 | 270 |
ABAT,KMO,STXBP1 |
| 2.203e-03 | -6.12 | SHETH_LIVER_CANCER_VS_TXNIP_LOSS_PAM4 | MSigDB lists | SHETH_LIVER_CANCER_VS_TXNIP_LOSS_PAM4 | 244 | 11 | 17377 | 282 |
ACSL1,PDK1,RECK,CFHR1,HEBP1,CYP4V2,NDRG2,ABAT,PLEKHB1,EPDR1,TBC1D8 |
| 2.208e-03 | -6.12 | GO_REGULATION_OF_GTPASE_ACTIVITY | MSigDB lists | GO_REGULATION_OF_GTPASE_ACTIVITY | 650 | 21 | 17377 | 282 |
ARHGAP26,RGS16,RASAL2,ARHGEF11,DOCK1,BVES,SPATA13,ARL2,WNT11,TBC1D16,TIAM2,RGS17,RALGPS2,GNAO1,RASGRF2,PLEKHG1,SRGAP1,ARHGAP28,DAB2IP,IQSEC2,TBC1D8 |
| 2.211e-03 | -6.11 | haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-mantle_cell_lymphoma | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-mantle_cell_lymphoma | 2807 | 64 | 17385 | 281 |
ARHGAP26,LONRF1,SCN5A,CCDC148,MXI1,TMEM132C,ZNF516,ZHX3,DOCK1,BVES,CHADL,ITPR2,COLEC10,PRKCA,KIF21B,DYNC1I1,RADIL,CBLN1,HMCN1,NEO1,MTUS1,PPM1E,ZNF827,RALGPS2,ZNF521,GTF2F2,SRGAP1,EEPD1,PRICKLE2,MYH15,TMEM37,MOXD1,DNAH5,STXBP1,FANK1,TMC7,DZANK1,PHLDB2,KLHL23,SFXN4,WDR25,WWC1,TNS1,LHPP,ACVR2B,B4GALNT3,RERE,CTIF,IQCK,TCF7L1,TRIB3,ADAMTS3,ISM1,WFS1,RASGRF2,LRRIQ3,WWTR1,P4HA1,ARHGAP28,MYOM2,DLX2,KLHL31,RNF157,COBL |
| 2.211e-03 | -6.11 | PH | pfam domains | PF00169 | 178 | 9 | 17054 | 271 |
ARHGAP26,PHLDB2,PLEKHA1,RALGPS2,GRK3,RASGRF2,PLEKHB1,TIAM2,SPATA13 |
| 2.212e-03 | -6.11 | protein phosphorylation | biological process | GO:0006468 | 956 | 27 | 17256 | 270 |
IL17RD,ACVR1,PDK1,RASAL2,PTPN6,NUAK2,STRADB,WNT11,GAS6,ACVR2B,SGK2,PRKCA,GRK3,DYRK1B,TRIB3,FGR,RASGRF2,PLK2,RPS6KL1,MAP2K6,MYC,PRKCD,ERN1,SGK1,DAB2IP,MAPK13,EPHB6 |
| 2.213e-03 | -6.11 | AGC_KINASE_CTER | prosite domains | PS51285 | 55 | 5 | 12060 | 202 |
SGK1,SGK2,PRKCA,GRK3,PRKCD |
| 2.231e-03 | -6.11 | nucleoside-triphosphatase regulator activity | molecular function | GO:0060589 | 360 | 14 | 17224 | 278 |
ARHGAP26,RGS16,RGS17,RASAL2,ARHGEF11,DOCK1,SRGAP1,ARL2,ARHGAP28,DAB2IP,WNT11,TBC1D16,TIAM2,TBC1D8 |
| 2.245e-03 | -6.10 | BROWNE_HCMV_INFECTION_24HR_DN | MSigDB lists | BROWNE_HCMV_INFECTION_24HR_DN | 142 | 8 | 17377 | 282 |
B9D1,UROS,RECK,BNIP3L,ACTA2,DBP,GAS6,PRKCA |
| 2.248e-03 | -6.10 | human chr10q26.2 | chromosome location | human chr10q26.2 | 21 | 3 | 26185 | 331 |
UROS,DOCK1,FANK1 |
| 2.249e-03 | -6.10 | RIGGINS_TAMOXIFEN_RESISTANCE_DN | MSigDB lists | RIGGINS_TAMOXIFEN_RESISTANCE_DN | 209 | 10 | 17377 | 282 |
MSX1,MXI1,PMAIP1,KIF5C,SATB2,ABAT,RAB38,PALLD,PLEKHB1,NT5DC2 |
| 2.285e-03 | -6.08 | human chr19q13.11 | chromosome location | human chr19q13.11 | 44 | 4 | 26185 | 331 |
RHPN2,CEBPA,KCTD15,KIAA0355 |
| 2.295e-03 | -6.08 | intracellular signal transduction | biological process | GO:0035556 | 1663 | 41 | 17256 | 270 |
RASAL2,ARHGEF11,DOCK1,ITPR2,GAS6,PRKCA,TIAM2,NCS1,RALGPS2,PMAIP1,GPR155,MYC,PRKCD,SGK1,INAVA,DAB2IP,BNIP3,PDE4D,RAB27B,TSHR,IL17RD,PDK1,PTPN6,NUAK2,ADCY1,STRADB,WWC1,RAB38,PLEKHA1,SAV1,SGK2,TLR6,TRIB3,MAP2K6,RASGRF2,PLK2,WWTR1,ERN1,TNFSF15,MAPK13,DDIT3 |
| 2.296e-03 | -6.08 | acute_myeloid_leukaemia_therapy_related | COSMIC cancer mutations | acute_myeloid_leukaemia_therapy_related | 1558 | 40 | 17385 | 281 |
ARHGAP26,LONRF1,TMEM63C,MXI1,DOCK1,ARHGEF11,CYP2J2,PLXNA2,SETBP1,CEBPA,ITPR2,SATB1,DYNC1I1,HMCN1,FHOD3,PPM1E,ZNF827,ZNF521,MYH15,DNAH5,TSHR,EPB41L5,QSOX1,IL17RD,BDNF,ADCY1,NLGN4X,SATB2,PRDM1,PALLD,JAM3,ADAMTS3,WFS1,GNAO1,RASGRF2,MAP2K6,LRRIQ3,HK2,CLMN,TANC2 |
| 2.296e-03 | -6.08 | haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-acute_myeloid_leukaemia_therapy_related | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-acute_myeloid_leukaemia_therapy_related | 1558 | 40 | 17385 | 281 |
ARHGAP26,LONRF1,TMEM63C,MXI1,DOCK1,ARHGEF11,CYP2J2,PLXNA2,SETBP1,CEBPA,ITPR2,SATB1,DYNC1I1,HMCN1,FHOD3,PPM1E,ZNF827,ZNF521,MYH15,DNAH5,TSHR,EPB41L5,QSOX1,IL17RD,BDNF,ADCY1,NLGN4X,SATB2,PRDM1,PALLD,JAM3,ADAMTS3,WFS1,GNAO1,RASGRF2,MAP2K6,LRRIQ3,HK2,CLMN,TANC2 |
| 2.299e-03 | -6.08 | chr10q26 | MSigDB lists | chr10q26 | 83 | 6 | 17377 | 282 |
BNIP3,LHPP,PLEKHA1,DOCK1,FANK1,SFXN4 |
| 2.305e-03 | -6.07 | mantle_cell_lymphoma | COSMIC cancer mutations | mantle_cell_lymphoma | 2920 | 66 | 17385 | 281 |
ARHGAP26,ZNF516,DOCK1,ITPR2,COLEC10,PRKCA,KIF21B,RADIL,CBLN1,HMCN1,PPM1E,ZNF827,ZNF521,EEPD1,MYH15,TMEM37,DNAH5,FANK1,DZANK1,PHLDB2,KLHL23,SFXN4,TNS1,TTC22,ACVR2B,IQCK,TCF7L1,WFS1,RASGRF2,WWTR1,P4HA1,ARHGAP28,DLX2,KLHL31,COBL,LONRF1,SCN5A,TMEM132C,MXI1,CCDC148,BVES,ZHX3,CHADL,DYNC1I1,MTUS1,NEO1,RALGPS2,SRGAP1,GTF2F2,PRICKLE2,MOXD1,STXBP1,TMC7,OGDHL,WWC1,WDR25,LHPP,B4GALNT3,CTIF,RERE,TRIB3,ADAMTS3,ISM1,LRRIQ3,MYOM2,RNF157 |
| 2.305e-03 | -6.07 | positive regulation of nitrogen compound metabolic process | biological process | GO:0051173 | 2965 | 65 | 17256 | 270 |
LONRF1,RUNX2,ACSL1,ZNF516,ACVR1,NECAB2,LGR4,ARHGEF11,FBXO4,SLX1B,CEBPA,GAS6,TNFRSF10C,OVOL2,ABAT,ZNF219,PRKCA,PFN2,KDM7A,EPCAM,PMAIP1,DACT1,MYC,PRKCD,RASD2,GTF2F2,EBF4,INAVA,DAB2IP,EPHB6,TSHR,FANK1,BARX1,HSPA2,GPR161,PARP9,SLC40A1,MSX1,SOX21,EFNA3,ADCY1,MAFB,STRADB,WWC1,GAREM1,WNT11,SATB2,PXYLP1,ACVR2B,ARRDC4,TLR6,RERE,GPLD1,DYRK1B,TRIB3,PLK2,WFS1,MAP2K6,ERN1,WWTR1,TNFSF15,DLX2,DBP,SMYD3,DDIT3 |
| 2.307e-03 | -6.07 | cell morphogenesis | biological process | GO:0000902 | 677 | 21 | 17256 | 270 |
EPB41L5,BDNF,MSX1,BVES,ST14,PTPN6,PLXNA2,EFNA3,ADCY1,KIF5C,STRADB,PRKCA,PALLD,RADIL,RERE,NEO1,NUMBL,SGK1,DAB2IP,STXBP1,COBL |
| 2.339e-03 | -6.06 | FOSL1 (FOS like 1, AP-1 transcription factor subunit) | protein interactions | 8061 | 34 | 4 | 17029 | 283 |
MAFB,CEBPA,MYC,DDIT3 |
| 2.355e-03 | -6.05 | MODULE_255 | MSigDB lists | MODULE_255 | 400 | 15 | 17377 | 282 |
SPNS1,ACVR1,ACSL1,ADAMTS3,MAP2K6,ALDOA,PLEKHG1,WDR25,PRDM1,EPHB6,PDE4D,SAV1,CBLN1,PKIA,RERE |
| 2.363e-03 | -6.05 | GSE6259_BCELL_VS_CD8_TCELL_UP | MSigDB lists | GSE6259_BCELL_VS_CD8_TCELL_UP | 176 | 9 | 17377 | 282 |
MN1,ZNF395,EEPD1,KIF5C,TNS1,CEBPA,RAB38,PKIA,TBC1D8 |
| 2.363e-03 | -6.05 | GSE5542_UNTREATED_VS_IFNG_TREATED_EPITHELIAL_CELLS_24H_DN | MSigDB lists | GSE5542_UNTREATED_VS_IFNG_TREATED_EPITHELIAL_CELLS_24H_DN | 176 | 9 | 17377 | 282 |
LMLN,FMO4,CYP2J2,MYC,PLXNA2,NDRG2,ARRDC4,RNF157,ZNF391 |
| 2.363e-03 | -6.05 | GSE2706_2H_VS_8H_R848_STIM_DC_UP | MSigDB lists | GSE2706_2H_VS_8H_R848_STIM_DC_UP | 176 | 9 | 17377 | 282 |
QSOX1,IQCK,ZNF697,MPP1,BACE1,BLVRB,SGK1,KIAA0513,ABAT |
| 2.364e-03 | -6.05 | branching morphogenesis of a nerve | biological process | GO:0048755 | 5 | 2 | 17256 | 270 |
DLX2,RERE |
| 2.364e-03 | -6.05 | renal sodium ion transport | biological process | GO:0003096 | 5 | 2 | 17256 | 270 |
SGK1,KLHL3 |
| 2.364e-03 | -6.05 | response to sorbitol | biological process | GO:0072708 | 5 | 2 | 17256 | 270 |
MAPK13,MAP2K6 |
| 2.364e-03 | -6.05 | mitochondrial protein catabolic process | biological process | GO:0035694 | 5 | 2 | 17256 | 270 |
BNIP3,BNIP3L |
| 2.364e-03 | -6.05 | extraocular skeletal muscle development | biological process | GO:0002074 | 5 | 2 | 17256 | 270 |
MYOM2,MYH15 |
| 2.392e-03 | -6.04 | SHAFFER_IRF4_MULTIPLE_MYELOMA_PROGRAM | MSigDB lists | SHAFFER_IRF4_MULTIPLE_MYELOMA_PROGRAM | 35 | 4 | 17377 | 282 |
P4HA1,PRDM1,TNFRSF17,MYC |
| 2.392e-03 | -6.04 | SEMENZA_HIF1_TARGETS | MSigDB lists | SEMENZA_HIF1_TARGETS | 35 | 4 | 17377 | 282 |
BNIP3,GAPDH,ALDOA,HK2 |
| 2.429e-03 | -6.02 | GO_NEGATIVE_REGULATION_OF_PLATELET_ACTIVATION | MSigDB lists | GO_NEGATIVE_REGULATION_OF_PLATELET_ACTIVATION | 17 | 3 | 17377 | 282 |
ABAT,UBASH3B,PRKCD |
| 2.429e-03 | -6.02 | GO_POSITIVE_REGULATION_OF_MITOCHONDRIAL_MEMBRANE_PERMEABILITY | MSigDB lists | GO_POSITIVE_REGULATION_OF_MITOCHONDRIAL_MEMBRANE_PERMEABILITY | 17 | 3 | 17377 | 282 |
BNIP3,PMAIP1,BNIP3L |
| 2.432e-03 | -6.02 | regulation of epithelial to mesenchymal transition | biological process | GO:0010717 | 87 | 6 | 17256 | 270 |
EPB41L5,DAB2IP,PHLDB2,OVOL2,ACVR1,WWTR1 |
| 2.432e-03 | -6.02 | regulation of actomyosin structure organization | biological process | GO:0110020 | 87 | 6 | 17256 | 270 |
ARHGAP28,PHLDB2,WNT11,PPM1E,PXN,PFN2 |
| 2.432e-03 | -6.02 | roof of mouth development | biological process | GO:0060021 | 87 | 6 | 17256 | 270 |
SATB2,WNT11,MSX1,ACVR2B,PLEKHA1,DLX6 |
| 2.433e-03 | -6.02 | testis-germ_cell_tumour-seminoma | COSMIC cancer mutations | testis-germ_cell_tumour-seminoma | 658 | 21 | 17385 | 281 |
ACVR1,PDK1,NUAK2,PLXNA2,RHPN2,STRADB,ACVR2B,SGK2,PRKCA,TBC1D16,DYRK1B,PPM1E,TRIB3,FGR,PLK2,RPS6KL1,MAP2K6,PRKCD,ERN1,SGK1,MAPK13 |
| 2.443e-03 | -6.01 | GO_PALATE_DEVELOPMENT | MSigDB lists | GO_PALATE_DEVELOPMENT | 84 | 6 | 17377 | 282 |
SATB2,WNT11,MSX1,ACVR2B,PLEKHA1,DLX6 |
| 2.443e-03 | -6.01 | IVANOVSKA_MIR106B_TARGETS | MSigDB lists | IVANOVSKA_MIR106B_TARGETS | 84 | 6 | 17377 | 282 |
KIAA0513,KIF5C,SLC40A1,NCEH1,GPR137C,PKIA |
| 2.447e-03 | -6.01 | positive regulation of osteoblast differentiation | biological process | GO:0045669 | 60 | 5 | 17256 | 270 |
CEBPA,RUNX2,ACVR2B,ACVR1,ZHX3 |
| 2.447e-03 | -6.01 | purine nucleoside diphosphate metabolic process | biological process | GO:0009135 | 60 | 5 | 17256 | 270 |
GAPDH,MPP1,ALDOA,OGDHL,HK2 |
| 2.447e-03 | -6.01 | purine ribonucleoside diphosphate metabolic process | biological process | GO:0009179 | 60 | 5 | 17256 | 270 |
GAPDH,MPP1,ALDOA,OGDHL,HK2 |
| 2.455e-03 | -6.01 | GSE22886_NAIVE_VS_IGM_MEMORY_BCELL_UP | MSigDB lists | GSE22886_NAIVE_VS_IGM_MEMORY_BCELL_UP | 177 | 9 | 17377 | 282 |
SLC30A4,ZHX3,FBXO4,PLK2,BACE1,ACVR2B,EXOG,ABHD4,SATB1 |
| 2.455e-03 | -6.01 | GO_REGULATION_OF_RAS_PROTEIN_SIGNAL_TRANSDUCTION | MSigDB lists | GO_REGULATION_OF_RAS_PROTEIN_SIGNAL_TRANSDUCTION | 177 | 9 | 17377 | 282 |
RASAL2,RALGPS2,ARHGEF11,RASGRF2,SPATA13,PLEKHG1,DAB2IP,IQSEC2,TIAM2 |
| 2.459e-03 | -6.01 | GO_MOVEMENT_OF_CELL_OR_SUBCELLULAR_COMPONENT | MSigDB lists | GO_MOVEMENT_OF_CELL_OR_SUBCELLULAR_COMPONENT | 1213 | 33 | 17377 | 282 |
SCN5A,ACVR1,ARHGEF11,DOCK1,BVES,PLXNA2,KIF5C,OVOL2,GAS6,KIF21B,DYNC1I1,NEO1,PRKCD,DAB2IP,PDE4D,DNAH5,PARP9,EPB41L5,BDNF,PTPN6,EFNA3,SPATA13,WWC1,WNT11,TNS1,SATB2,PALLD,JAM3,CENPV,RERE,GPLD1,IFT81,FGR |
| 2.464e-03 | -6.01 | TK1 (thymidine kinase 1) | protein interactions | 7083 | 173 | 9 | 17029 | 283 |
GAPDH,KLHL23,DACT1,MPP1,KIF21B,ABHD4,DYNC1I1,TIAM2,NCS1 |
| 2.467e-03 | -6.00 | NAKAMURA_TUMOR_ZONE_PERIPHERAL_VS_CENTRAL_DN | MSigDB lists | NAKAMURA_TUMOR_ZONE_PERIPHERAL_VS_CENTRAL_DN | 569 | 19 | 17377 | 282 |
MXI1,PDK1,PNRC1,ZNF395,BNIP3L,NRN1,TNS1,SAV1,ABHD6,SATB1,RERE,EBF4,HK2,P4HA1,TNFSF15,BNIP3,PDE4D,IQSEC2,RAB27B |
| 2.467e-03 | -6.00 | GO_POSITIVE_REGULATION_OF_OSTEOBLAST_DIFFERENTIATION | MSigDB lists | GO_POSITIVE_REGULATION_OF_OSTEOBLAST_DIFFERENTIATION | 58 | 5 | 17377 | 282 |
CEBPA,ACVR2B,ACVR1,RUNX2,ZHX3 |
| 2.467e-03 | -6.00 | PID_FAK_PATHWAY | MSigDB lists | PID_FAK_PATHWAY | 58 | 5 | 17377 | 282 |
ARHGAP26,PXN,ARHGEF11,DOCK1,PTPN21 |
| 2.530e-03 | -5.98 | MYH11 (myosin heavy chain 11) | protein interactions | 4629 | 57 | 5 | 17029 | 283 |
ACTA2,SLX1B,LGR4,DSTN,MPP1 |
| 2.530e-03 | -5.98 | GNAO1 (G protein subunit alpha o1) | protein interactions | 2775 | 57 | 5 | 17029 | 283 |
RGS16,SLC30A4,TSHR,KLHL3,GNAO1 |
| 2.531e-03 | -5.98 | RGS | interpro domains | IPR016137 | 36 | 4 | 18492 | 296 |
RGS17,RGS16,ARHGEF11,GRK3 |
| 2.544e-03 | -5.97 | GO_REGULATION_OF_KINASE_ACTIVITY | MSigDB lists | GO_REGULATION_OF_KINASE_ACTIVITY | 747 | 23 | 17377 | 282 |
ACSL1,DUSP8,UBASH3B,PTPN6,ADCY1,STRADB,CEBPA,WNT11,ACVR2B,GAS6,TLR6,TRIB3,PPM1E,FGR,MAP2K6,ERN1,WWTR1,PRKCD,TNFSF15,DAB2IP,HSPA2,SMYD3,PKIA |
| 2.550e-03 | -5.97 | GSE22886_NEUTROPHIL_VS_MONOCYTE_UP | MSigDB lists | GSE22886_NEUTROPHIL_VS_MONOCYTE_UP | 178 | 9 | 17377 | 282 |
GPR63,NECAB2,RECK,OGDHL,NLGN4X,TNFRSF10C,OVOL2,CBLN1,GPLD1 |
| 2.562e-03 | -5.97 | central_nervous_system-brain-glioma | COSMIC cancer mutations | central_nervous_system-brain-glioma | 15942 | 270 | 17385 | 281 |
ARHGAP26,ACVR1,DUSP8,LGR4,RECK,LSM11,ALG1L,CEBPA,PRKCA,ABHD6,NCS1,EPDR1,PMAIP1,CFHR1,TMEM37,TSHR,KLHL23,KLHL3,WISP3,EXOC6B,DSTN,BNIP3L,SLC25A28,ABCC2,TNS1,ACVR2B,SAV1,SPATA9,PLK2,RASGRF2,ALDOA,ARHGAP28,MAPK13,TMOD2,TANC2,SCN5A,ZHX3,CYP2J2,SLC36A4,TNFRSF10C,DYNC1I1,HPCAL4,NIPSNAP3B,MTUS1,IL17D,RALGPS2,MYC,ZIC5,SRGAP1,MOXD1,STXBP1,GPR161,EPB41L5,BDNF,QSOX1,SHISA2,ARRDC4,OR11H4,ZNF558,ADAMTS3,ISM1,LRRIQ3,QPCTL,EMILIN2,CLMN,IQSEC2,SMYD3,ZNF516,RASAL2,ST14,FAM131C,CCDC110,PLXNA2,COLEC10,TIAM2,TMEM53,ZNF827,KMO,DACT1,DAB2IP,PJA1,PDE4D,RAB27B,DNAH5,ATP6AP1L,KIAA1549,C3orf67,GAPDH,PDK1,SOX21,CYB5R2,SFXN4,ADCY1,NLGN4X,SATB2,WNT11,RAB38,TBC1D16,IQCK,WFS1,WWTR1,PLEKHG1,P4HA1,TNFSF15,DBP,COBL,KCTD1,C2orf88,CCDC148,MXI1,TMEM132C,BACE1,BIK,CCNJL,KIF5C,ARL2,GAS6,ZNF219,NEO1,RGS17,GPR155,SMPDL3A,PARP9,TMC7,MN1,B9D1,SLC40A1,PXN,MPP1,GPR137C,GPLD1,TRIB3,FGR,GNAO1,MYOM2,TNFRSF17,DDIT3,B4GALT7,PHC1,CCDC126,ACSL1,HEBP1,PTPN21,NDRG2,NRN1,ABAT,ITPR2,SLC2A13,ABHD4,HMCN1,EPCAM,PPM1E,FKBP9,CPNE2,MARVELD2,DLX6,TMEM143,TLN2,FANK1,OR2W3,ZNF391,PGBD5,PNRC1,CAPN5,TTC22,PLEKHA1,SGK2,NT5DC2,PLEKHB1,DYRK1B,SPNS1,TCF7L1,ERN1,DLX2,APBA2,GPR63,LONRF1,RGS16,RUNX2,ZNF395,BVES,FBXO4,UBASH3B,CYP4V2,ATP6V1E2,RASL11B,SETBP1,CHADL,SATB1,PFN2,FHOD3,NUMBL,SLC30A4,GAN,EBF4,BNIP3,NCEH1,VGLL4,BARX1,IL17RD,SPATA13,EFNA3,MAFB,STRADB,WWC1,WDR25,PPFIA4,LHPP,PRDM1,B4GALNT3,KIAA0355,HK2,RNF122,DOCK1,RHPN2,FAM198B,KIF21B,RADIL,CBLN1,KCTD15,RPS6KL1,EEPD1,ZDHHC23,ZNF521,MAP7,MYH15,TMEM120B,HSPA2,FAM78B,PHLDB2,UROS,PTPN6,SLC39A8,JAM3,CENPV,IFT81,LMLN,ANKRD31,RBPMS2,DISP1,NECAB2,PRSS16,ARHGEF11,BLVRB,OVOL2,PRKCD,RASD2,EHD3,GTF2F2,ACTA2,PRICKLE2,TRIM3,SGK1,CCDC122,KIAA0408,MSX1,NUAK2,OGDHL,EXOG,PALLD,TLR6,CTIF,RERE,FMO4,MAP2K6,KIAA0513,ZNF474,THAP10,RNF157,PKIA |
| 2.567e-03 | -5.97 | testis-germ_cell_tumour-non_seminoma | COSMIC cancer mutations | testis-germ_cell_tumour-non_seminoma | 488 | 17 | 17385 | 281 |
ACVR1,PDK1,NUAK2,STRADB,ACVR2B,SGK2,PRKCA,DYRK1B,TRIB3,FGR,RPS6KL1,MAP2K6,PLK2,ERN1,PRKCD,SGK1,MAPK13 |
| 2.575e-03 | -5.96 | GO_CELL_MOTILITY | MSigDB lists | GO_CELL_MOTILITY | 793 | 24 | 17377 | 282 |
EPB41L5,ACVR1,DOCK1,BVES,PTPN6,SPATA13,PLXNA2,WWC1,SATB2,TNS1,WNT11,OVOL2,GAS6,PALLD,JAM3,CENPV,GPLD1,RERE,FGR,PRKCD,DAB2IP,PDE4D,DNAH5,PARP9 |
| 2.575e-03 | -5.96 | GO_LOCALIZATION_OF_CELL | MSigDB lists | GO_LOCALIZATION_OF_CELL | 793 | 24 | 17377 | 282 |
EPB41L5,ACVR1,DOCK1,BVES,PTPN6,SPATA13,PLXNA2,WWC1,SATB2,TNS1,WNT11,OVOL2,GAS6,PALLD,JAM3,CENPV,GPLD1,RERE,FGR,PRKCD,DAB2IP,PDE4D,DNAH5,PARP9 |
| 2.597e-03 | -5.95 | negative regulation of platelet activation | biological process | GO:0010544 | 18 | 3 | 17256 | 270 |
ABAT,UBASH3B,PRKCD |
| 2.605e-03 | -5.95 | positive regulation of cell death | biological process | GO:0010942 | 684 | 21 | 17256 | 270 |
MSX1,GAPDH,ARHGEF11,BIK,BNIP3L,WNT11,SAV1,TLR6,TIAM2,GPLD1,PMAIP1,KMO,RASGRF2,MAP2K6,MYC,PRKCD,TNFSF15,DAB2IP,BNIP3,FANK1,DDIT3 |
| 2.648e-03 | -5.93 | PRC2_EZH2_UP.V1_DN | MSigDB lists | PRC2_EZH2_UP.V1_DN | 179 | 9 | 17377 | 282 |
TMC7,RGS17,RGS16,DUSP8,KIAA0513,SETBP1,COLEC10,PKIA,SMPDL3A |
| 2.648e-03 | -5.93 | TGFB_UP.V1_UP | MSigDB lists | TGFB_UP.V1_UP | 179 | 9 | 17377 | 282 |
TMC7,DACT1,CYP2J2,MAFB,SGK1,WNT11,PLEKHA1,OVOL2,PKIA |
| 2.664e-03 | -5.93 | RGS | prosite domains | PS50132 | 35 | 4 | 12060 | 202 |
RGS17,RGS16,ARHGEF11,GRK3 |
| 2.668e-03 | -5.93 | GO_INTRINSIC_APOPTOTIC_SIGNALING_PATHWAY | MSigDB lists | GO_INTRINSIC_APOPTOTIC_SIGNALING_PATHWAY | 146 | 8 | 17377 | 282 |
DAB2IP,BNIP3,TRIB3,PDK1,PMAIP1,PRKCD,DDIT3,ERN1 |
| 2.668e-03 | -5.93 | GO_PEPTIDYL_SERINE_MODIFICATION | MSigDB lists | GO_PEPTIDYL_SERINE_MODIFICATION | 146 | 8 | 17377 | 282 |
PLK2,PRKCD,ERN1,SGK1,MAPK13,GAS6,PRKCA,SGK2 |
| 2.684e-03 | -5.92 | cellular developmental process | biological process | GO:0048869 | 3666 | 77 | 17256 | 270 |
ZNF516,ACVR1,LGR4,ST14,PLXNA2,NDRG2,CEBPA,PRKCA,RADIL,CBLN1,NCS1,EPCAM,DLX6,MARVELD2,ZNF521,DAB2IP,EPHB6,PDE4D,TMEM120B,HSPA2,SLC9C1,SOX21,PTPN6,ADCY1,NLGN4X,SATB2,WNT11,ACVR2B,RAB38,PLEKHA1,SAV1,JAM3,SPATA9,DYRK1B,TCF7L1,PLK2,WWTR1,TMOD2,DLX2,COBL,RUNX2,ZHX3,BVES,KIF5C,GAS6,OVOL2,HERC6,SATB1,FHOD3,MYORG,NEO1,NUMBL,PRKCD,ZIC5,SGK1,ACTA2,BNIP3,STXBP1,BARX1,EPB41L5,B9D1,LZTS3,BDNF,ENAM,MSX1,EFNA3,MAFB,STRADB,PRDM1,PALLD,GPLD1,RERE,FGR,GNAO1,CLMN,MYOM2,SMYD3 |
| 2.712e-03 | -5.91 | GO_NEGATIVE_REGULATION_OF_PHOSPHORYLATION | MSigDB lists | GO_NEGATIVE_REGULATION_OF_PHOSPHORYLATION | 406 | 15 | 17377 | 282 |
PPM1E,TRIB3,DUSP8,PTPN6,MYC,UBASH3B,DACT1,PRKCD,WWTR1,NDRG2,DAB2IP,CEBPA,PDE4D,SMYD3,PKIA |
| 2.723e-03 | -5.91 | phosphate-containing compound metabolic process | biological process | GO:0006796 | 2050 | 48 | 17256 | 270 |
ACVR1,DUSP8,RASAL2,UBASH3B,PTPN21,GAS6,PRKCA,ABHD6,ABHD4,PPM1E,KMO,RPS6KL1,MYC,PRKCD,SGK1,DAB2IP,PDE4D,EPHB6,SMPDL3A,PARP9,IL17RD,GAPDH,PDK1,MPP1,PTPN6,NUAK2,OGDHL,ADCY1,STRADB,WNT11,PXYLP1,ACVR2B,PLEKHA1,LHPP,SGK2,GRK3,NT5DC2,GPLD1,DYRK1B,TRIB3,FGR,RASGRF2,PLK2,MAP2K6,ALDOA,ERN1,HK2,MAPK13 |
| 2.727e-03 | -5.90 | regulation of actin filament bundle assembly | biological process | GO:0032231 | 89 | 6 | 17256 | 270 |
ARHGAP28,PHLDB2,WNT11,PPM1E,PXN,PFN2 |
| 2.748e-03 | -5.90 | GSE12366_PLASMA_CELL_VS_NAIVE_BCELL_DN | MSigDB lists | GSE12366_PLASMA_CELL_VS_NAIVE_BCELL_DN | 180 | 9 | 17377 | 282 |
FGR,ZNF395,KIAA0355,PTPN6,MYC,PLEKHG1,HERC6,SATB1,JAM3 |
| 2.770e-03 | -5.89 | seminoma | COSMIC cancer mutations | seminoma | 710 | 22 | 17385 | 281 |
ACVR1,PDK1,NUAK2,PLXNA2,RHPN2,STRADB,ACVR2B,SGK2,PRKCA,TBC1D16,DYRK1B,PPM1E,TRIB3,FGR,PLK2,RPS6KL1,MAP2K6,PRKCD,ERN1,PRICKLE2,SGK1,MAPK13 |
| 2.811e-03 | -5.87 | RODRIGUES_THYROID_CARCINOMA_POORLY_DIFFERENTIATED_DN | MSigDB lists | RODRIGUES_THYROID_CARCINOMA_POORLY_DIFFERENTIATED_DN | 708 | 22 | 17377 | 282 |
EPB41L5,SLC40A1,MXI1,PNRC1,RECK,HEBP1,SPATA13,WWC1,TNS1,ABAT,NEO1,RERE,EPCAM,IGIP,MARVELD2,ACTA2,PRICKLE2,CLMN,SGK1,MAPK13,VGLL4,SMPDL3A |
| 2.827e-03 | -5.87 | ribonucleoside diphosphate metabolic process | biological process | GO:0009185 | 62 | 5 | 17256 | 270 |
GAPDH,MPP1,ALDOA,OGDHL,HK2 |
| 2.848e-03 | -5.86 | positive regulation of response to endoplasmic reticulum stress | biological process | GO:1905898 | 38 | 4 | 17256 | 270 |
DAB2IP,PMAIP1,DDIT3,ERN1 |
| 2.848e-03 | -5.86 | glycolytic process | biological process | GO:0006096 | 38 | 4 | 17256 | 270 |
GAPDH,ALDOA,OGDHL,HK2 |
| 2.849e-03 | -5.86 | non_seminoma | COSMIC cancer mutations | non_seminoma | 493 | 17 | 17385 | 281 |
ACVR1,PDK1,NUAK2,STRADB,ACVR2B,SGK2,PRKCA,DYRK1B,TRIB3,FGR,RPS6KL1,MAP2K6,PLK2,ERN1,PRKCD,SGK1,MAPK13 |
| 2.852e-03 | -5.86 | GSE3982_BCELL_VS_CENT_MEMORY_CD4_TCELL_UP | MSigDB lists | GSE3982_BCELL_VS_CENT_MEMORY_CD4_TCELL_UP | 181 | 9 | 17377 | 282 |
CLMN,TRIB3,FGR,SAV1,TNFRSF17,TSHR,DACT1,EHD3,HK2 |
| 2.852e-03 | -5.86 | GSE24634_TEFF_VS_TCONV_DAY5_IN_CULTURE_DN | MSigDB lists | GSE24634_TEFF_VS_TCONV_DAY5_IN_CULTURE_DN | 181 | 9 | 17377 | 282 |
PDK1,ZNF395,ST14,KIAA0355,HEBP1,KIAA0513,SLC25A28,TNFSF15,PLEKHB1 |
| 2.852e-03 | -5.86 | GSE11057_CD4_CENT_MEM_VS_PBMC_DN | MSigDB lists | GSE11057_CD4_CENT_MEM_VS_PBMC_DN | 181 | 9 | 17377 | 282 |
ACSL1,PRKCD,SETBP1,KIAA0513,CEBPA,TNFSF15,NCEH1,TLR6,TBC1D8 |
| 2.857e-03 | -5.86 | VEGFA-VEGFR2 Pathway | REACTOME pathways | R-HSA-4420097 | 330 | 12 | 10287 | 148 |
IL17RD,TRIB3,PXN,RASAL2,DUSP8,DOCK1,RASGRF2,PRKCD,DAB2IP,MAPK13,ITPR2,PRKCA |
| 2.868e-03 | -5.85 | IVANOVA_HEMATOPOIESIS_STEM_CELL_LONG_TERM | MSigDB lists | IVANOVA_HEMATOPOIESIS_STEM_CELL_LONG_TERM | 290 | 12 | 17377 | 282 |
TCF7L1,RASAL2,PTPN21,MAP7,SETBP1,TNS1,MAPK13,PRDM1,PLEKHA1,TMEM37,SMYD3,JAM3 |
| 2.894e-03 | -5.85 | TUBA8 (tubulin alpha 8) | protein interactions | 51807 | 36 | 4 | 17029 | 283 |
PXN,LGR4,MYC,GAN |
| 2.916e-03 | -5.84 | MODULE_426 | MSigDB lists | MODULE_426 | 87 | 6 | 17377 | 282 |
MAP7,KIF5C,SPNS1,GAS6,DYNC1I1,RPS6KL1 |
| 2.920e-03 | -5.84 | Myometrial Relaxation and Contraction Pathways | WikiPathways | WP289 | 158 | 9 | 5312 | 101 |
RGS17,RGS16,PRKCD,ADCY1,ACTA2,ITPR2,PDE4D,PRKCA,PKIA |
| 2.938e-03 | -5.83 | plasma membrane bounded cell projection | cellular component | GO:0120025 | 1984 | 46 | 18223 | 280 |
NECAB2,BVES,BACE1,C4A,BLVRB,ARL2,KIF5C,NDRG2,ABAT,KIF21B,PFN2,TIAM2,NCS1,RGS17,EHD3,ACTA2,TRIM3,DAB2IP,BNIP3,EPHB6,TLN2,DNAH5,STXBP1,GPR161,EPB41L5,B9D1,BDNF,PXN,SLC9C1,MPP1,SPATA13,WWC1,NLGN4X,ABCC2,CATSPERE,PLEKHA1,PALLD,OR11H4,IFT81,FGR,PLK2,GNAO1,WFS1,TMOD2,APBA2,COBL |
| 2.942e-03 | -5.83 | GO_ATP_GENERATION_FROM_ADP | MSigDB lists | GO_ATP_GENERATION_FROM_ADP | 37 | 4 | 17377 | 282 |
GAPDH,ALDOA,OGDHL,HK2 |
| 2.952e-03 | -5.83 | spinal_cord | COSMIC cancer mutations | spinal_cord | 149 | 8 | 17385 | 281 |
TRIB3,QSOX1,ACSL1,ACVR1,PRICKLE2,CEBPA,TSHR,KIAA1549 |
| 2.959e-03 | -5.82 | GSE22229_RENAL_TRANSPLANT_VS_HEALTHY_PBMC_DN | MSigDB lists | GSE22229_RENAL_TRANSPLANT_VS_HEALTHY_PBMC_DN | 182 | 9 | 17377 | 282 |
ZNF827,TRIB3,KIAA0355,GPR155,CYP4V2,RAB38,STXBP1,ABHD4,PHC1 |
| 2.959e-03 | -5.82 | GSE29618_PRE_VS_DAY7_POST_LAIV_FLU_VACCINE_BCELL_DN | MSigDB lists | GSE29618_PRE_VS_DAY7_POST_LAIV_FLU_VACCINE_BCELL_DN | 182 | 9 | 17377 | 282 |
BDNF,IFT81,TCF7L1,KIF5C,DBP,PRDM1,EXOG,ABHD4,PGBD5 |
| 2.959e-03 | -5.82 | GSE42088_UNINF_VS_LEISHMANIA_INF_DC_8H_DN | MSigDB lists | GSE42088_UNINF_VS_LEISHMANIA_INF_DC_8H_DN | 182 | 9 | 17377 | 282 |
DZANK1,GPR63,RGS17,WWTR1,ABCC2,FHOD3,PHC1,ZNF391,MTUS1 |
| 2.963e-03 | -5.82 | negative regulation of protein kinase activity | biological process | GO:0006469 | 263 | 11 | 17256 | 270 |
TRIB3,PPM1E,DUSP8,PTPN6,UBASH3B,PRKCD,WWTR1,DAB2IP,CEBPA,SMYD3,PKIA |
| 2.964e-03 | -5.82 | intrinsic apoptotic signaling pathway | biological process | GO:0097193 | 154 | 8 | 17256 | 270 |
TRIB3,DAB2IP,BNIP3,PDK1,PMAIP1,PRKCD,DDIT3,ERN1 |
| 2.964e-03 | -5.82 | ameboidal-type cell migration | biological process | GO:0001667 | 154 | 8 | 17256 | 270 |
EPB41L5,WNT11,TNS1,PXN,OVOL2,ACVR1,CENPV,GPLD1 |
| 3.027e-03 | -5.80 | GO_EPITHELIAL_CELL_DIFFERENTIATION | MSigDB lists | GO_EPITHELIAL_CELL_DIFFERENTIATION | 452 | 16 | 17377 | 282 |
B9D1,EPB41L5,ACVR1,ST14,CAPN5,WNT11,PRDM1,ACVR2B,OVOL2,SAV1,PALLD,MARVELD2,DLX6,ACTA2,PDE4D,BARX1 |
| 3.032e-03 | -5.80 | negative regulation of synaptic transmission | biological process | GO:0050805 | 63 | 5 | 17256 | 270 |
NLGN4X,ABHD6,STXBP1,PLK2,CBLN1 |
| 3.049e-03 | -5.79 | V$CEBP_Q2 | MSigDB lists | V$CEBP_Q2 | 218 | 10 | 17377 | 282 |
TCF7L1,BDNF,RASAL2,MAP2K6,PDE4D,COLEC10,PFN2,TBC1D16,DDIT3,NEO1 |
| 3.057e-03 | -5.79 | AB_hydrolase | interpro domains | IPR029058 | 119 | 7 | 18492 | 296 |
NLGN4X,NDRG2,TMEM53,PRSS16,NCEH1,ABHD4,ABHD6 |
| 3.061e-03 | -5.79 | catalytic activity, acting on a protein | molecular function | GO:0140096 | 2313 | 54 | 17224 | 278 |
LONRF1,CCDC126,ACVR1,PRSS16,DUSP8,ST14,C4A,FBXO4,UBASH3B,BACE1,PTPN21,COLEC10,HERC6,PRKCA,KDM7A,PPM1E,FKBP9,RPS6KL1,PRKCD,GAN,ZDHHC23,TRIM3,SGK1,EPHB6,PJA1,QSOX1,GAPDH,PDK1,KLHL3,KLHL23,PTPN6,CAPN5,EFNA3,NUAK2,STRADB,LHPP,ACVR2B,SGK2,B4GALNT3,GRK3,DYRK1B,FGR,LMLN,ADAMTS3,PLK2,MAP2K6,ERN1,QPCTL,P4HA1,MAPK13,KLHL31,RNF122,SMYD3,B4GALT7 |
| 3.066e-03 | -5.79 | pancreas-carcinoma-ductal_carcinoma | COSMIC cancer mutations | pancreas-carcinoma-ductal_carcinoma | 16044 | 271 | 17385 | 281 |
ARHGAP26,ACVR1,DUSP8,LGR4,RECK,LSM11,ALG1L,CEBPA,PRKCA,ABHD6,NCS1,EPDR1,PMAIP1,CFHR1,TMEM37,TSHR,TBC1D8,KLHL23,KLHL3,WISP3,EXOC6B,DSTN,BNIP3L,SLC25A28,ABCC2,TNS1,ACVR2B,SAV1,SPATA9,PLK2,RASGRF2,ALDOA,ARHGAP28,MAPK13,TMOD2,SCN5A,TMEM63C,ZHX3,CYP2J2,SLC36A4,TNFRSF10C,DYNC1I1,HPCAL4,NIPSNAP3B,MTUS1,IL17D,RALGPS2,MYC,ZIC5,SRGAP1,MOXD1,STXBP1,GPR161,EPB41L5,BDNF,QSOX1,SHISA2,ARRDC4,OR11H4,ZNF558,ADAMTS3,ISM1,LRRIQ3,QPCTL,EMILIN2,CLMN,IQSEC2,SMYD3,ZNF516,RASAL2,ST14,C4A,FAM131C,CCDC110,PLXNA2,COLEC10,TIAM2,TMEM53,ZNF827,KMO,DACT1,DAB2IP,PJA1,PDE4D,RAB27B,DNAH5,ATP6AP1L,KIAA1549,C3orf67,GAPDH,PDK1,SOX21,CYB5R2,SFXN4,ADCY1,NLGN4X,SATB2,WNT11,RAB38,TBC1D16,IQCK,WFS1,WWTR1,PLEKHG1,P4HA1,TNFSF15,DBP,COBL,KCTD1,C2orf88,CCDC148,MXI1,TMEM132C,BACE1,BIK,CCNJL,KIF5C,ARL2,GAS6,ZNF219,NEO1,RGS17,GPR155,SMPDL3A,PARP9,TMC7,MN1,B9D1,SLC40A1,PXN,MPP1,GPR137C,GPLD1,TRIB3,FGR,GNAO1,MYOM2,TNFRSF17,DDIT3,B4GALT7,PHC1,CCDC126,ACSL1,HEBP1,PTPN21,NDRG2,NRN1,ABAT,ITPR2,SLC2A13,ABHD4,HMCN1,EPCAM,PPM1E,FKBP9,CPNE2,DLX6,TMEM143,TLN2,FANK1,OR2W3,ZNF391,PGBD5,PNRC1,CAPN5,TTC22,PLEKHA1,SGK2,NT5DC2,PLEKHB1,DYRK1B,SPNS1,TCF7L1,ERN1,DLX2,APBA2,GPR63,LONRF1,RGS16,RUNX2,ZNF395,BVES,FBXO4,UBASH3B,CYP4V2,ATP6V1E2,RASL11B,SETBP1,CHADL,SATB1,PFN2,FHOD3,NUMBL,SLC30A4,GAN,EBF4,BNIP3,NCEH1,VGLL4,BARX1,IL17RD,SPATA13,EFNA3,MAFB,STRADB,WWC1,WDR25,PPFIA4,LHPP,PRDM1,B4GALNT3,KIAA0355,HK2,RNF122,DOCK1,RHPN2,FAM198B,KIF21B,RADIL,CBLN1,KCTD15,RPS6KL1,EEPD1,ZDHHC23,ZNF521,MAP7,MYH15,TMEM120B,HSPA2,FAM78B,PHLDB2,UROS,PTPN6,SLC39A8,JAM3,CENPV,IFT81,LMLN,ANKRD31,RBPMS2,DISP1,NECAB2,PRSS16,ARHGEF11,BLVRB,OVOL2,PRKCD,RASD2,EHD3,GTF2F2,ACTA2,PRICKLE2,TRIM3,SGK1,CCDC122,KIAA0408,MSX1,NUAK2,OGDHL,EXOG,PALLD,TLR6,CTIF,RERE,FMO4,MAP2K6,KIAA0513,ZNF474,THAP10,RNF157,PKIA |
| 3.069e-03 | -5.79 | P53_DN.V1_DN | MSigDB lists | P53_DN.V1_DN | 183 | 9 | 17377 | 282 |
ZNF516,ADCY1,SGK1,ACTA2,ABCC2,MYOM2,COLEC10,HSPA2,MTUS1 |
| 3.069e-03 | -5.79 | GSE13522_CTRL_VS_T_CRUZI_Y_STRAIN_INF_SKIN_129_MOUSE_DN | MSigDB lists | GSE13522_CTRL_VS_T_CRUZI_Y_STRAIN_INF_SKIN_129_MOUSE_DN | 183 | 9 | 17377 | 282 |
TCF7L1,ARHGEF11,RECK,RBPMS2,ZNF521,CYP4V2,KIF5C,SAV1,PFN2 |
| 3.069e-03 | -5.79 | GSE21379_WT_VS_SAP_KO_TFH_CD4_TCELL_UP | MSigDB lists | GSE21379_WT_VS_SAP_KO_TFH_CD4_TCELL_UP | 183 | 9 | 17377 | 282 |
FKBP9,ZNF697,DOCK1,SGK1,SHISA2,MAPK13,LHPP,PALLD,MTUS1 |
| 3.069e-03 | -5.79 | KAECH_NAIVE_VS_MEMORY_CD8_TCELL_UP | MSigDB lists | KAECH_NAIVE_VS_MEMORY_CD8_TCELL_UP | 183 | 9 | 17377 | 282 |
MAP7,PLEKHA1,SLC30A4,PDK1,RALGPS2,TLR6,MPP1,WFS1,RERE |
| 3.069e-03 | -5.79 | GSE19198_6H_VS_24H_IL21_TREATED_TCELL_DN | MSigDB lists | GSE19198_6H_VS_24H_IL21_TREATED_TCELL_DN | 183 | 9 | 17377 | 282 |
ARHGAP26,TNS1,TMEM37,ZNF395,TBC1D16,MPP1,MYC,BLVRB,RERE |
| 3.079e-03 | -5.78 | GOTTWEIN_TARGETS_OF_KSHV_MIR_K12_11 | MSigDB lists | GOTTWEIN_TARGETS_OF_KSHV_MIR_K12_11 | 61 | 5 | 17377 | 282 |
SGK1,C2orf88,KIAA0408,SCAMP1,ABHD6 |
| 3.087e-03 | -5.78 | GO_ENDOTHELIUM_DEVELOPMENT | MSigDB lists | GO_ENDOTHELIUM_DEVELOPMENT | 88 | 6 | 17377 | 282 |
SLC40A1,ACVR2B,OVOL2,ACVR1,PDE4D,MARVELD2 |
| 3.135e-03 | -5.77 | ATP generation from ADP | biological process | GO:0006757 | 39 | 4 | 17256 | 270 |
GAPDH,ALDOA,OGDHL,HK2 |
| 3.182e-03 | -5.75 | GSE9650_NAIVE_VS_MEMORY_CD8_TCELL_UP | MSigDB lists | GSE9650_NAIVE_VS_MEMORY_CD8_TCELL_UP | 184 | 9 | 17377 | 282 |
PDK1,SLC30A4,RALGPS2,MPP1,WFS1,MAP7,P4HA1,PLEKHA1,TLR6 |
| 3.182e-03 | -5.75 | GSE36476_CTRL_VS_TSST_ACT_72H_MEMORY_CD4_TCELL_OLD_UP | MSigDB lists | GSE36476_CTRL_VS_TSST_ACT_72H_MEMORY_CD4_TCELL_OLD_UP | 184 | 9 | 17377 | 282 |
MXI1,ZNF516,PDK1,ZNF395,GNAO1,SGK1,PLEKHA1,PFN2,JAM3 |
| 3.182e-03 | -5.75 | GSE21546_SAP1A_KO_VS_SAP1A_KO_AND_ELK1_KO_ANTI_CD3_STIM_DP_THYMOCYTES_UP | MSigDB lists | GSE21546_SAP1A_KO_VS_SAP1A_KO_AND_ELK1_KO_ANTI_CD3_STIM_DP_THYMOCYTES_UP | 184 | 9 | 17377 | 282 |
EPB41L5,KIAA0355,GPR155,HEBP1,EHD3,PLXNA2,STRADB,CENPV,EPDR1 |
| 3.188e-03 | -5.75 | cell communication | biological process | GO:0007154 | 5463 | 107 | 17256 | 270 |
ARHGAP26,ACSL1,ZNF516,ACVR1,LGR4,RASAL2,DOCK1,HEBP1,PLXNA2,RHPN2,NDRG2,CEBPA,ITPR2,PRKCA,CACNB4,RADIL,CBLN1,TIAM2,NCS1,EPCAM,PMAIP1,DACT1,RPS6KL1,DAB2IP,PDE4D,EPHB6,RAB27B,OR2W3,TSHR,PDK1,WISP3,PTPN6,CAPN5,BNIP3L,ADCY1,WNT11,ACVR2B,RAB38,PLEKHA1,SGK2,SAV1,JAM3,GRK3,PLEKHB1,SPNS1,TCF7L1,RASGRF2,PLK2,WFS1,ERN1,WWTR1,ARHGAP28,TNFSF15,MAPK13,TMOD2,DISP1,APBA2,GPR63,SCN5A,RGS16,RUNX2,ARHGEF11,UBASH3B,ATP6V1E2,RASL11B,GAS6,TNFRSF10C,ZNF219,HPCAL4,NEO1,NUMBL,RALGPS2,GPR155,MYC,PRKCD,RASD2,GTF2F2,SRGAP1,SGK1,PRICKLE2,INAVA,BNIP3,STXBP1,BARX1,GPR161,B9D1,IL17RD,BDNF,PXN,MSX1,MPP1,NUAK2,EFNA3,PPFIA4,WWC1,STRADB,GAREM1,ARRDC4,OR11H4,TLR6,GPLD1,TRIB3,FGR,MAP2K6,GNAO1,TNFRSF17,DDIT3 |
| 3.205e-03 | -5.74 | GnRH signaling pathway | KEGG pathways | hsa04912 | 92 | 6 | 7161 | 113 |
MAPK13,ITPR2,PRKCA,MAP2K6,PRKCD,ADCY1 |
| 3.205e-03 | -5.74 | GnRH signaling pathway | KEGG pathways | ko04912 | 92 | 6 | 7161 | 113 |
MAPK13,ITPR2,PRKCA,MAP2K6,PRKCD,ADCY1 |
| 3.209e-03 | -5.74 | Signaling by Hippo | REACTOME pathways | R-HSA-2028269 | 21 | 3 | 10287 | 148 |
WWC1,SAV1,WWTR1 |
| 3.220e-03 | -5.74 | ACTIVIN2R | prints domains | PR00653 | 6 | 2 | 4652 | 70 |
ACVR2B,ACVR1 |
| 3.220e-03 | -5.74 | GLYCHORMONER | prints domains | PR00373 | 6 | 2 | 4652 | 70 |
LGR4,TSHR |
| 3.231e-03 | -5.73 | GO_POSITIVE_REGULATION_OF_CELLULAR_COMPONENT_BIOGENESIS | MSigDB lists | GO_POSITIVE_REGULATION_OF_CELLULAR_COMPONENT_BIOGENESIS | 373 | 14 | 17377 | 282 |
EPB41L5,BDNF,PPM1E,PHLDB2,PMAIP1,BIK,GTF2F2,ARL2,WNT11,PRKCA,PFN2,TLR6,COBL,CBLN1 |
| 3.234e-03 | -5.73 | Rho_GTPase_activation_prot | interpro domains | IPR008936 | 90 | 6 | 18492 | 296 |
ARHGAP28,ARHGAP26,DAB2IP,RASAL2,PLXNA2,SRGAP1 |
| 3.247e-03 | -5.73 | PID_RAC1_REG_PATHWAY | MSigDB lists | PID_RAC1_REG_PATHWAY | 38 | 4 | 17377 | 282 |
DOCK1,RASGRF2,TIAM2,SPATA13 |
| 3.286e-03 | -5.72 | cell differentiation | biological process | GO:0030154 | 3578 | 75 | 17256 | 270 |
ZNF516,ACVR1,LGR4,ST14,PLXNA2,NDRG2,CEBPA,PRKCA,RADIL,CBLN1,NCS1,EPCAM,DLX6,MARVELD2,ZNF521,DAB2IP,EPHB6,PDE4D,TMEM120B,HSPA2,SLC9C1,SOX21,PTPN6,ADCY1,NLGN4X,SATB2,WNT11,ACVR2B,RAB38,PLEKHA1,SAV1,JAM3,SPATA9,DYRK1B,TCF7L1,PLK2,WWTR1,TMOD2,DLX2,COBL,RUNX2,ZHX3,BVES,KIF5C,GAS6,OVOL2,HERC6,SATB1,FHOD3,MYORG,NEO1,NUMBL,ZIC5,SGK1,ACTA2,BNIP3,STXBP1,BARX1,EPB41L5,B9D1,LZTS3,BDNF,ENAM,MSX1,EFNA3,MAFB,PRDM1,PALLD,GPLD1,RERE,FGR,GNAO1,CLMN,MYOM2,SMYD3 |
| 3.299e-03 | -5.71 | GSE5589_LPS_AND_IL10_VS_LPS_AND_IL6_STIM_IL10_KO_MACROPHAGE_45MIN_DN | MSigDB lists | GSE5589_LPS_AND_IL10_VS_LPS_AND_IL6_STIM_IL10_KO_MACROPHAGE_45MIN_DN | 185 | 9 | 17377 | 282 |
ARHGAP26,LMLN,SLC30A4,ST14,UBASH3B,EXOC6B,FAM198B,STXBP1,MTUS1 |
| 3.306e-03 | -5.71 | GO_RIBONUCLEOSIDE_DIPHOSPHATE_METABOLIC_PROCESS | MSigDB lists | GO_RIBONUCLEOSIDE_DIPHOSPHATE_METABOLIC_PROCESS | 62 | 5 | 17377 | 282 |
GAPDH,MPP1,ALDOA,OGDHL,HK2 |
| 3.336e-03 | -5.70 | ovary-carcinoma-clear_cell_carcinoma | COSMIC cancer mutations | ovary-carcinoma-clear_cell_carcinoma | 676 | 21 | 17385 | 281 |
ACVR1,PDK1,ZHX3,NUAK2,NDRG2,NLGN4X,STRADB,ACVR2B,SGK2,PRKCA,B4GALNT3,DYRK1B,TRIB3,FGR,PLK2,RPS6KL1,MAP2K6,PRKCD,ERN1,SGK1,MAPK13 |
| 3.361e-03 | -5.70 | V$HNF6_Q6 | MSigDB lists | V$HNF6_Q6 | 221 | 10 | 17377 | 282 |
MN1,ZNF827,KCTD15,GNAO1,GTF2F2,PRICKLE2,DLX2,PFN2,RERE,MTUS1 |
| 3.380e-03 | -5.69 | KAMIKUBO_MYELOID_MN1_NETWORK | MSigDB lists | KAMIKUBO_MYELOID_MN1_NETWORK | 19 | 3 | 17377 | 282 |
SGK1,MN1,MTUS1 |
| 3.405e-03 | -5.68 | RGS_sf | interpro domains | IPR036305 | 39 | 4 | 18492 | 296 |
RGS17,RGS16,ARHGEF11,GRK3 |
| 3.407e-03 | -5.68 | HELZ (helicase with zinc finger) | protein interactions | 9931 | 61 | 5 | 17029 | 283 |
CCNJL,SAV1,SMYD3,MYC,GAN |
| 3.415e-03 | -5.68 | C2_domain_sf | interpro domains | IPR035892 | 154 | 8 | 18492 | 296 |
CPNE2,RASAL2,DOCK1,PRKCD,CAPN5,WWC1,DAB2IP,PRKCA |
| 3.417e-03 | -5.68 | GO_RUFFLE | MSigDB lists | GO_RUFFLE | 152 | 8 | 17377 | 282 |
EPB41L5,FGR,SPATA13,WWC1,PLEKHA1,PALLD,TLN2,COBL |
| 3.418e-03 | -5.68 | GSE1432_1H_VS_6H_IFNG_MICROGLIA_UP | MSigDB lists | GSE1432_1H_VS_6H_IFNG_MICROGLIA_UP | 186 | 9 | 17377 | 282 |
ARHGAP26,FKBP9,LGR4,MAP2K6,MPP1,PLXNA2,SATB2,ABHD6,SATB1 |
| 3.418e-03 | -5.68 | GSE22886_IL2_VS_IL15_STIM_NKCELL_UP | MSigDB lists | GSE22886_IL2_VS_IL15_STIM_NKCELL_UP | 186 | 9 | 17377 | 282 |
FKBP9,GNAO1,EPHB6,ITPR2,SGK2,TLN2,CBLN1,NIPSNAP3B,TIAM2 |
| 3.418e-03 | -5.68 | GO_STEM_CELL_DIFFERENTIATION | MSigDB lists | GO_STEM_CELL_DIFFERENTIATION | 186 | 9 | 17377 | 282 |
EPB41L5,EPCAM,MSX1,ACVR1,RUNX2,SOX21,WWTR1,WNT11,OVOL2 |
| 3.441e-03 | -5.67 | anatomical structure formation involved in morphogenesis | biological process | GO:0048646 | 842 | 24 | 17256 | 270 |
EPB41L5,ENAM,SLC40A1,MSX1,ACVR1,ST14,PTPN6,PLXNA2,MAFB,WNT11,ACVR2B,OVOL2,ZNF219,PRKCA,JAM3,CBLN1,FHOD3,GPLD1,DYRK1B,DLX6,TMOD2,DAB2IP,MYOM2,COBL |
| 3.450e-03 | -5.67 | multicellular organismal process | biological process | GO:0032501 | 6701 | 127 | 17256 | 270 |
ARHGAP26,ZNF516,ACVR1,LGR4,ST14,DOCK1,RECK,PLXNA2,NDRG2,NRN1,CEBPA,ITPR2,ABAT,PRKCA,CACNB4,RADIL,HMCN1,CBLN1,NCS1,EPCAM,KCTD15,DACT1,DLX6,MARVELD2,ZNF521,DAB2IP,MYH15,PDE4D,EPHB6,OR2W3,DNAH5,TSHR,HSPA2,TBC1D8,KLHL3,SLC9C1,SOX21,PTPN6,ADCY1,NLGN4X,SATB2,WNT11,ABCC2,ACVR2B,PLEKHA1,SAV1,JAM3,PLEKHB1,SPATA9,DYRK1B,IFT81,TCF7L1,PLK2,WFS1,RBPMS2,WWTR1,ALDOA,TMOD2,DISP1,DBP,DLX2,TANC2,APBA2,COBL,SCN5A,RGS16,RUNX2,ARHGEF11,BVES,UBASH3B,BIK,CYP4V2,KIF5C,GAS6,OVOL2,TNFRSF10C,HERC6,ZNF219,SATB1,HPCAL4,MYORG,FHOD3,NEO1,KDM7A,NUMBL,MYC,GPR155,ZIC5,PRKCD,EHD3,EBF4,ACTA2,SGK1,TRIM3,INAVA,BNIP3,NCEH1,STXBP1,BARX1,GPR161,EPB41L5,B9D1,MN1,SLC40A1,ENAM,LZTS3,BDNF,PXN,MSX1,EFNA3,MAFB,SHISA2,PRDM1,PALLD,OR11H4,TLR6,RERE,GPLD1,ADAMTS3,MAP2K6,GNAO1,HK2,CLMN,MYOM2,TNFRSF17,DDIT3,PHC1 |
| 3.456e-03 | -5.67 | biological regulation | biological process | GO:0065007 | 12133 | 210 | 17256 | 270 |
ARHGAP26,ACSL1,ACVR1,DUSP8,LGR4,RECK,HEBP1,LSM11,NDRG2,CEBPA,ITPR2,ABAT,PRKCA,CACNB4,ABHD6,ABHD4,NCS1,EPCAM,PPM1E,PMAIP1,DLX6,CFHR1,TMEM37,EPHB6,TLN2,OR2W3,TSHR,FANK1,ZNF391,TBC1D8,PNRC1,SLC9C1,KLHL3,WISP3,DSTN,ATOX1,CAPN5,BNIP3L,SLC25A28,ABCC2,ACVR2B,PLEKHA1,SGK2,SAV1,GRK3,PLEKHB1,SPNS1,DYRK1B,TCF7L1,PLK2,RASGRF2,ERN1,ALDOA,ARHGAP28,MAPK13,TMOD2,DLX2,APBA2,LONRF1,GPR63,SCN5A,RGS16,RUNX2,ZNF395,ZHX3,BVES,CYP2J2,FBXO4,UBASH3B,ATP6V1E2,SETBP1,RASL11B,CHADL,TNFRSF10C,SATB1,DYNC1I1,PFN2,HPCAL4,MYORG,FHOD3,MTUS1,IL17D,NUMBL,SLC30A4,RALGPS2,MYC,ZIC5,SRGAP1,EBF4,INAVA,BNIP3,MOXD1,NCEH1,VGLL4,STXBP1,BARX1,GPR161,EPB41L5,ENAM,BDNF,QSOX1,IL17RD,EFNA3,SPATA13,PPFIA4,WWC1,MAFB,STRADB,SHISA2,PRDM1,OR11H4,ARRDC4,ZNF558,ADAMTS3,HK2,CLMN,IQSEC2,SMYD3,ZNF516,RASAL2,DOCK1,C4A,PLXNA2,RHPN2,COLEC10,RADIL,CBLN1,TIAM2,ZNF827,KMO,DACT1,RPS6KL1,ZNF521,DAB2IP,PDE4D,RAB27B,KIAA1549,HSPA2,PHLDB2,GAPDH,PDK1,SLC39A8,SOX21,PTPN6,SFXN4,ADCY1,NLGN4X,WNT11,SATB2,PXYLP1,RAB38,TBC1D16,JAM3,CENPV,ZNF697,RBPMS2,WFS1,WWTR1,PLEKHG1,TNFSF15,DISP1,DBP,KLHL31,COBL,KCTD1,NECAB2,MXI1,ARHGEF11,BACE1,BIK,ARL2,SLX1B,GAS6,OVOL2,ZNF219,NEO1,KDM7A,RGS17,GPR155,PRKCD,EHD3,RASD2,GTF2F2,ACTA2,SGK1,PRICKLE2,PARP9,B9D1,MN1,SLC40A1,LZTS3,PXN,MSX1,MPP1,NUAK2,GAREM1,TLR6,RERE,GPLD1,CTIF,TRIB3,FGR,GNAO1,MAP2K6,THAP10,TNFRSF17,B4GALT7,DDIT3,PKIA,PHC1 |
| 3.470e-03 | -5.66 | Signaling by VEGF | REACTOME pathways | R-HSA-194138 | 338 | 12 | 10287 | 148 |
IL17RD,TRIB3,PXN,RASAL2,DUSP8,DOCK1,RASGRF2,PRKCD,DAB2IP,MAPK13,ITPR2,PRKCA |
| 3.474e-03 | -5.66 | apoptotic mitochondrial changes | biological process | GO:0008637 | 65 | 5 | 17256 | 270 |
BNIP3,PMAIP1,BIK,BNIP3L,HK2 |
| 3.494e-03 | -5.66 | regulation of cellular process | biological process | GO:0050794 | 10836 | 191 | 17256 | 270 |
ARHGAP26,ACSL1,ACVR1,DUSP8,LGR4,RECK,HEBP1,LSM11,NDRG2,CEBPA,ITPR2,ABAT,PRKCA,ABHD6,NCS1,EPCAM,PPM1E,PMAIP1,DLX6,CFHR1,EPHB6,OR2W3,TSHR,FANK1,ZNF391,TBC1D8,PNRC1,WISP3,DSTN,CAPN5,BNIP3L,ACVR2B,PLEKHA1,SGK2,SAV1,GRK3,PLEKHB1,SPNS1,DYRK1B,TCF7L1,PLK2,RASGRF2,ERN1,ALDOA,ARHGAP28,MAPK13,TMOD2,DLX2,LONRF1,GPR63,SCN5A,RGS16,RUNX2,ZNF395,ZHX3,BVES,FBXO4,UBASH3B,ATP6V1E2,SETBP1,RASL11B,CHADL,TNFRSF10C,SATB1,PFN2,HPCAL4,MYORG,FHOD3,MTUS1,IL17D,NUMBL,SLC30A4,RALGPS2,MYC,ZIC5,SRGAP1,EBF4,INAVA,BNIP3,VGLL4,STXBP1,BARX1,GPR161,EPB41L5,ENAM,BDNF,QSOX1,IL17RD,EFNA3,SPATA13,WWC1,MAFB,STRADB,SHISA2,PRDM1,OR11H4,ARRDC4,ZNF558,ADAMTS3,HK2,CLMN,IQSEC2,SMYD3,ZNF516,RASAL2,DOCK1,C4A,PLXNA2,RHPN2,RADIL,CBLN1,TIAM2,ZNF827,KMO,DACT1,RPS6KL1,ZNF521,DAB2IP,PDE4D,RAB27B,KIAA1549,HSPA2,PHLDB2,GAPDH,PDK1,SOX21,PTPN6,ADCY1,NLGN4X,WNT11,SATB2,PXYLP1,RAB38,TBC1D16,JAM3,CENPV,ZNF697,RBPMS2,WFS1,WWTR1,PLEKHG1,TNFSF15,DISP1,DBP,KLHL31,COBL,KCTD1,NECAB2,MXI1,ARHGEF11,BACE1,BIK,ARL2,SLX1B,GAS6,OVOL2,ZNF219,NEO1,KDM7A,RGS17,GPR155,PRKCD,EHD3,RASD2,GTF2F2,SGK1,PRICKLE2,PARP9,B9D1,MN1,SLC40A1,LZTS3,PXN,MSX1,MPP1,NUAK2,GAREM1,TLR6,RERE,GPLD1,CTIF,TRIB3,FGR,GNAO1,MAP2K6,THAP10,TNFRSF17,B4GALT7,DDIT3,PKIA,PHC1 |
| 3.510e-03 | -5.65 | BMP signaling pathway involved in heart development | biological process | GO:0061312 | 6 | 2 | 17256 | 270 |
MSX1,ACVR1 |
| 3.510e-03 | -5.65 | negative regulation of mitochondrial membrane permeability | biological process | GO:0035795 | 6 | 2 | 17256 | 270 |
BNIP3,HK2 |
| 3.510e-03 | -5.65 | negative regulation of membrane permeability | biological process | GO:1905709 | 6 | 2 | 17256 | 270 |
BNIP3,HK2 |
| 3.516e-03 | -5.65 | RGS | smart domains | SM00315 | 35 | 4 | 9493 | 172 |
RGS17,RGS16,ARHGEF11,GRK3 |
| 3.534e-03 | -5.65 | GNA12 (G protein subunit alpha 12) | protein interactions | 2768 | 38 | 4 | 17029 | 283 |
PRKCA,TSHR,ARHGEF11,PRKCD |
| 3.542e-03 | -5.64 | GSE17721_PAM3CSK4_VS_GADIQUIMOD_4H_BMDC_DN | MSigDB lists | GSE17721_PAM3CSK4_VS_GADIQUIMOD_4H_BMDC_DN | 187 | 9 | 17377 | 282 |
EPB41L5,DOCK1,MPP1,SPATA13,SLC25A28,PRDM1,SAV1,BARX1,TBC1D8 |
| 3.542e-03 | -5.64 | GSE2770_UNTREATED_VS_IL4_TREATED_ACT_CD4_TCELL_6H_UP | MSigDB lists | GSE2770_UNTREATED_VS_IL4_TREATED_ACT_CD4_TCELL_6H_UP | 187 | 9 | 17377 | 282 |
CCDC126,FKBP9,IGIP,MPP1,BNIP3L,TSHR,SMPDL3A,PARP9,GPLD1 |
| 3.546e-03 | -5.64 | positive regulation of mitochondrial membrane permeability involved in apoptotic process | biological process | GO:1902110 | 20 | 3 | 17256 | 270 |
BNIP3,PMAIP1,BNIP3L |
| 3.558e-03 | -5.64 | DODD_NASOPHARYNGEAL_CARCINOMA_UP | MSigDB lists | DODD_NASOPHARYNGEAL_CARCINOMA_UP | 1490 | 38 | 17377 | 282 |
CCDC148,RASAL2,ZNF395,ST14,BACE1,PTPN21,RHPN2,NDRG2,ABAT,ABHD6,NIPSNAP3B,TMEM53,RALGPS2,EHD3,PRKCD,FANK1,DNAH5,C3orf67,B9D1,DZANK1,QSOX1,PXN,KLHL3,CAPN5,WWC1,WDR25,ABCC2,TTC22,TNS1,RAB38,RERE,WFS1,LRRIQ3,KIAA0513,CLMN,ZNF474,DBP,COBL |
| 3.571e-03 | -5.63 | clear_cell_carcinoma | COSMIC cancer mutations | clear_cell_carcinoma | 680 | 21 | 17385 | 281 |
ACVR1,PDK1,ZHX3,NUAK2,NDRG2,NLGN4X,STRADB,ACVR2B,SGK2,PRKCA,B4GALNT3,DYRK1B,TRIB3,FGR,PLK2,RPS6KL1,MAP2K6,PRKCD,ERN1,SGK1,MAPK13 |
| 3.573e-03 | -5.63 | GO_TRANSITION_METAL_ION_TRANSMEMBRANE_TRANSPORTER_ACTIVITY | MSigDB lists | GO_TRANSITION_METAL_ION_TRANSMEMBRANE_TRANSPORTER_ACTIVITY | 39 | 4 | 17377 | 282 |
SLC40A1,SLC30A4,SLC39A8,ATOX1 |
| 3.573e-03 | -5.63 | GO_PROTEIN_SERINE_THREONINE_TYROSINE_KINASE_ACTIVITY | MSigDB lists | GO_PROTEIN_SERINE_THREONINE_TYROSINE_KINASE_ACTIVITY | 39 | 4 | 17377 | 282 |
SGK1,DYRK1B,ACVR2B,MAP2K6 |
| 3.580e-03 | -5.63 | GO_LOCOMOTION | MSigDB lists | GO_LOCOMOTION | 1049 | 29 | 17377 | 282 |
EPB41L5,BDNF,ACVR1,DOCK1,BVES,PTPN6,SPATA13,PLXNA2,EFNA3,KIF5C,WWC1,SATB2,TNS1,WNT11,OVOL2,GAS6,PALLD,JAM3,CENPV,GPLD1,NEO1,RERE,SPNS1,FGR,PRKCD,DAB2IP,PDE4D,DNAH5,PARP9 |
| 3.583e-03 | -5.63 | V$FOXO4_01 | MSigDB lists | V$FOXO4_01 | 223 | 10 | 17377 | 282 |
BDNF,MXI1,BIK,ZNF521,SLC25A28,SATB2,PRDM1,PDE4D,COLEC10,NEO1 |
| 3.597e-03 | -5.63 | CAGGTG_V$E12_Q6 | MSigDB lists | CAGGTG_V$E12_Q6 | 2317 | 54 | 17377 | 282 |
ARHGAP26,SCN5A,CCDC148,RASAL2,ZNF395,UBASH3B,BACE1,PLXNA2,OVOL2,ITPR2,ABHD4,HPCAL4,CBLN1,HMCN1,EPDR1,MTUS1,EPCAM,RGS17,ZNF827,NUMBL,KCTD15,MYC,RASD2,SRGAP1,ZNF521,MAP7,EPHB6,STXBP1,VGLL4,TBC1D8,EPB41L5,BDNF,GAPDH,KLHL3,DSTN,ATOX1,WWC1,WNT11,TNS1,PRDM1,ACVR2B,PALLD,PLEKHB1,FGR,KIAA0355,GNAO1,RASGRF2,ALDOA,ERN1,DLX2,DBP,RNF122,COBL,PKIA |
| 3.620e-03 | -5.62 | haematopoietic_and_lymphoid_tissue | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue | 14812 | 255 | 17385 | 281 |
ARHGAP26,CCDC126,ACSL1,ACVR1,DUSP8,LGR4,RECK,HEBP1,LSM11,PTPN21,ALG1L,NRN1,CEBPA,ITPR2,ABAT,PRKCA,ABHD4,CACNB4,ABHD6,HMCN1,NCS1,EPDR1,EPCAM,CPNE2,FKBP9,PPM1E,PMAIP1,MARVELD2,CFHR1,TMEM143,TMEM37,TLN2,OR2W3,TSHR,FANK1,TBC1D8,PGBD5,ZNF391,KLHL23,KLHL3,WISP3,EXOC6B,DSTN,CAPN5,BNIP3L,SLC25A28,TTC22,ABCC2,TNS1,PLEKHA1,ACVR2B,SGK2,SAV1,NT5DC2,PLEKHB1,SPNS1,DYRK1B,SPATA9,TCF7L1,PLK2,RASGRF2,ERN1,ALDOA,ARHGAP28,MAPK13,TMOD2,DLX2,TANC2,APBA2,LONRF1,GPR63,SCN5A,TMEM63C,RUNX2,ZNF395,SCART1,ZHX3,BVES,UBASH3B,CYP2J2,FBXO4,CYP4V2,SETBP1,ATP6V1E2,CHADL,SLC36A4,SATB1,DYNC1I1,HPCAL4,NIPSNAP3B,FHOD3,MTUS1,NUMBL,RALGPS2,SLC30A4,MYC,ZIC5,EBF4,SRGAP1,GAN,BNIP3,NCEH1,MOXD1,VGLL4,STXBP1,GPR161,EPB41L5,BDNF,IL17RD,QSOX1,EFNA3,SPATA13,PPFIA4,WDR25,WWC1,STRADB,SHISA2,PRDM1,LHPP,ARRDC4,OR11H4,B4GALNT3,ZNF558,KIAA0355,ADAMTS3,ISM1,LRRIQ3,QPCTL,EMILIN2,HK2,CLMN,IQSEC2,RNF122,SMYD3,ZNF516,RASAL2,DOCK1,ST14,FAM131C,C4A,CCDC110,PLXNA2,RHPN2,FAM198B,COLEC10,KIF21B,RADIL,CBLN1,TIAM2,TMEM53,ZNF827,KCTD15,KMO,RPS6KL1,DACT1,ZNF521,ZDHHC23,EEPD1,MAP7,DAB2IP,MYH15,PJA1,PDE4D,DNAH5,TMEM120B,FAM78B,ATP6AP1L,HSPA2,C3orf67,DZANK1,PHLDB2,GAPDH,UROS,PDK1,SLC39A8,PTPN6,CYB5R2,SFXN4,ADCY1,NLGN4X,SATB2,WNT11,RAB38,TBC1D16,JAM3,CENPV,IQCK,LMLN,ANKRD31,WFS1,RBPMS2,WWTR1,PLEKHG1,P4HA1,TNFSF15,DISP1,DBP,KLHL31,COBL,CCDC148,MXI1,TMEM132C,NECAB2,PRSS16,ARHGEF11,BACE1,BIK,BLVRB,CCNJL,KIF5C,OVOL2,ZNF219,NEO1,RGS17,GPR155,PRKCD,EHD3,RASD2,GTF2F2,ACTA2,CCDC122,TRIM3,PRICKLE2,SGK1,KIAA0408,SMPDL3A,PARP9,TMC7,MN1,B9D1,SLC40A1,MSX1,MPP1,OGDHL,NUAK2,PALLD,EXOG,TLR6,GPR137C,RERE,GPLD1,CTIF,TRIB3,FGR,MAP2K6,GNAO1,FMO4,KIAA0513,MYOM2,ZNF474,TNFRSF17,THAP10,RNF157,DDIT3,PHC1 |
| 3.630e-03 | -5.62 | Glycogenosis- Type IA. Von gierke disease | SMPDB pathways | SMP00581 | 22 | 3 | 992 | 15 |
GAPDH,ALDOA,HK2 |
| 3.630e-03 | -5.62 | Phosphoenolpyruvate carboxykinase deficiency 1 (PEPCK1) | SMPDB pathways | SMP00560 | 22 | 3 | 992 | 15 |
GAPDH,ALDOA,HK2 |
| 3.630e-03 | -5.62 | Triosephosphate isomerase | SMPDB pathways | SMP00563 | 22 | 3 | 992 | 15 |
GAPDH,ALDOA,HK2 |
| 3.630e-03 | -5.62 | Fructose-1-6-diphosphatase deficiency | SMPDB pathways | SMP00562 | 22 | 3 | 992 | 15 |
GAPDH,ALDOA,HK2 |
| 3.630e-03 | -5.62 | Glycogenosis- Type IB | SMPDB pathways | SMP00573 | 22 | 3 | 992 | 15 |
GAPDH,ALDOA,HK2 |
| 3.630e-03 | -5.62 | Glycogen Storage Disease Type 1A (GSD1A) or Von Gierke Disease | SMPDB pathways | SMP00374 | 22 | 3 | 992 | 15 |
GAPDH,ALDOA,HK2 |
| 3.630e-03 | -5.62 | Glycogenosis- Type IC | SMPDB pathways | SMP00574 | 22 | 3 | 992 | 15 |
GAPDH,ALDOA,HK2 |
| 3.630e-03 | -5.62 | Gluconeogenesis | SMPDB pathways | SMP00128 | 22 | 3 | 992 | 15 |
GAPDH,ALDOA,HK2 |
| 3.648e-03 | -5.61 | AMUNDSON_POOR_SURVIVAL_AFTER_GAMMA_RADIATION_8G | MSigDB lists | AMUNDSON_POOR_SURVIVAL_AFTER_GAMMA_RADIATION_8G | 91 | 6 | 17377 | 282 |
SGK1,KIF21B,DOCK1,PFN2,PLK2,WWTR1 |
| 3.665e-03 | -5.61 | negative regulation of protein phosphorylation | biological process | GO:0001933 | 435 | 15 | 17256 | 270 |
TRIB3,PPM1E,DUSP8,DACT1,PTPN6,MYC,UBASH3B,PRKCD,WWTR1,NDRG2,DAB2IP,CEBPA,PDE4D,SMYD3,PKIA |
| 3.668e-03 | -5.61 | GSE21670_STAT3_KO_VS_WT_CD4_TCELL_IL6_TREATED_DN | MSigDB lists | GSE21670_STAT3_KO_VS_WT_CD4_TCELL_IL6_TREATED_DN | 188 | 9 | 17377 | 282 |
TRIB3,PHLDB2,FKBP9,KIAA0355,MARVELD2,NDRG2,PALLD,PRKCA,PKIA |
| 3.668e-03 | -5.61 | GSE20715_0H_VS_6H_OZONE_LUNG_UP | MSigDB lists | GSE20715_0H_VS_6H_OZONE_LUNG_UP | 188 | 9 | 17377 | 282 |
FGR,UROS,DACT1,MPP1,ATOX1,BNIP3L,WNT11,RAB38,FAM198B |
| 3.668e-03 | -5.61 | GSE36826_NORMAL_VS_STAPH_AUREUS_INF_IL1R_KO_SKIN_UP | MSigDB lists | GSE36826_NORMAL_VS_STAPH_AUREUS_INF_IL1R_KO_SKIN_UP | 188 | 9 | 17377 | 282 |
IQCK,SCAMP1,LGR4,HEBP1,BLVRB,PLEKHA1,GAS6,TBC1D16,VGLL4 |
| 3.671e-03 | -5.61 | Gphrmn_rcpt_fam | interpro domains | IPR002131 | 6 | 2 | 18492 | 296 |
LGR4,TSHR |
| 3.674e-03 | -5.61 | primitive_neuroectodermal_tumour-medulloblastoma | COSMIC cancer mutations | primitive_neuroectodermal_tumour-medulloblastoma | 15815 | 268 | 17385 | 281 |
ARHGAP26,ACVR1,DUSP8,LGR4,RECK,LSM11,ALG1L,PRKCA,ABHD6,NCS1,EPDR1,PMAIP1,CFHR1,TMEM37,TSHR,TBC1D8,KLHL23,KLHL3,WISP3,EXOC6B,DSTN,BNIP3L,SLC25A28,ABCC2,TNS1,SAV1,SPATA9,PLK2,RASGRF2,ALDOA,ARHGAP28,MAPK13,TMOD2,TANC2,SCN5A,TMEM63C,ZHX3,CYP2J2,SLC36A4,TNFRSF10C,DYNC1I1,HPCAL4,NIPSNAP3B,MTUS1,IL17D,RALGPS2,MYC,ZIC5,SRGAP1,MOXD1,STXBP1,GPR161,EPB41L5,BDNF,QSOX1,SHISA2,ARRDC4,ZNF558,ADAMTS3,ISM1,LRRIQ3,QPCTL,EMILIN2,CLMN,IQSEC2,SMYD3,ZNF516,RASAL2,ST14,FAM131C,C4A,CCDC110,PLXNA2,COLEC10,TIAM2,TMEM53,ZNF827,KMO,DACT1,DAB2IP,PJA1,PDE4D,RAB27B,DNAH5,ATP6AP1L,KIAA1549,C3orf67,DZANK1,GAPDH,PDK1,SOX21,CYB5R2,SFXN4,ADCY1,NLGN4X,SATB2,WNT11,RAB38,TBC1D16,IQCK,ZNF697,WFS1,WWTR1,PLEKHG1,TNFSF15,DBP,KLHL31,COBL,KCTD1,CCDC148,MXI1,TMEM132C,BACE1,BIK,CCNJL,KIF5C,ARL2,GAS6,ZNF219,NEO1,RGS17,GPR155,SMPDL3A,PARP9,TMC7,MN1,B9D1,SLC40A1,PXN,MPP1,GPR137C,GPLD1,TRIB3,FGR,GNAO1,MYOM2,TNFRSF17,DDIT3,B4GALT7,PHC1,CCDC126,ACSL1,HEBP1,PTPN21,NDRG2,NRN1,ABAT,ITPR2,SLC2A13,CACNB4,ABHD4,HMCN1,EPCAM,PPM1E,FKBP9,CPNE2,MARVELD2,DLX6,TMEM143,TLN2,FANK1,ZNF391,PGBD5,PNRC1,CAPN5,TTC22,PLEKHA1,SGK2,NT5DC2,PLEKHB1,DYRK1B,SPNS1,TCF7L1,DLX2,APBA2,GPR63,LONRF1,RGS16,RUNX2,ZNF395,BVES,FBXO4,UBASH3B,CYP4V2,RASL11B,SETBP1,CHADL,SATB1,PFN2,FHOD3,SLC30A4,GAN,EBF4,BNIP3,NCEH1,VGLL4,BARX1,IL17RD,SPATA13,EFNA3,MAFB,STRADB,WWC1,WDR25,PPFIA4,LHPP,PRDM1,B4GALNT3,KIAA0355,HK2,RNF122,DOCK1,RHPN2,FAM198B,KIF21B,RADIL,CBLN1,KCTD15,RPS6KL1,EEPD1,ZDHHC23,ZNF521,MAP7,MYH15,TMEM120B,HSPA2,FAM78B,PHLDB2,UROS,PTPN6,SLC39A8,JAM3,CENPV,IFT81,LMLN,ANKRD31,RBPMS2,DISP1,NECAB2,PRSS16,ARHGEF11,BLVRB,OVOL2,RASD2,EHD3,PRKCD,GTF2F2,ACTA2,PRICKLE2,TRIM3,SGK1,CCDC122,KIAA0408,MSX1,NUAK2,OGDHL,EXOG,PALLD,TLR6,CTIF,RERE,FMO4,MAP2K6,KIAA0513,ZNF474,THAP10,RNF157,PKIA |
| 3.694e-03 | -5.60 | negative regulation of supramolecular fiber organization | biological process | GO:1902904 | 126 | 7 | 17256 | 270 |
ARHGAP28,CHADL,PHLDB2,TMOD2,PFN2,PRKCD,FHOD3 |
| 3.722e-03 | -5.59 | ZHOU_INFLAMMATORY_RESPONSE_LIVE_UP | MSigDB lists | ZHOU_INFLAMMATORY_RESPONSE_LIVE_UP | 420 | 15 | 17377 | 282 |
MN1,RGS16,ACSL1,PNRC1,RASAL2,KLHL3,PRKCD,SRGAP1,WWC1,TNFSF15,TNS1,SLC2A13,PALLD,DYNC1I1,COBL |
| 3.749e-03 | -5.59 | regulation of protein kinase activity | biological process | GO:0045859 | 800 | 23 | 17256 | 270 |
ACSL1,DUSP8,PTPN6,UBASH3B,ADCY1,STRADB,CEBPA,WNT11,GAS6,ACVR2B,TLR6,TRIB3,PPM1E,FGR,MAP2K6,PRKCD,WWTR1,ERN1,INAVA,TNFSF15,DAB2IP,SMYD3,PKIA |
| 3.769e-03 | -5.58 | regulation of binding | biological process | GO:0051098 | 352 | 13 | 17256 | 270 |
EPB41L5,TRIB3,BDNF,MSX1,DACT1,PLK2,CFHR1,UBASH3B,PRKCD,ARHGAP28,DAB2IP,DDIT3,PARP9 |
| 3.787e-03 | -5.58 | cell morphogenesis involved in differentiation | biological process | GO:0000904 | 524 | 17 | 17256 | 270 |
EPB41L5,BDNF,BVES,ST14,PTPN6,PLXNA2,EFNA3,ADCY1,KIF5C,PALLD,PRKCA,RADIL,RERE,NEO1,NUMBL,STXBP1,COBL |
| 3.795e-03 | -5.57 | GO_REGULATION_OF_EPITHELIAL_TO_MESENCHYMAL_TRANSITION | MSigDB lists | GO_REGULATION_OF_EPITHELIAL_TO_MESENCHYMAL_TRANSITION | 64 | 5 | 17377 | 282 |
EPB41L5,PHLDB2,DAB2IP,OVOL2,WWTR1 |
| 3.798e-03 | -5.57 | GSE39556_UNTREATED_VS_3H_POLYIC_INJ_MOUSE_CD8A_DC_UP | MSigDB lists | GSE39556_UNTREATED_VS_3H_POLYIC_INJ_MOUSE_CD8A_DC_UP | 189 | 9 | 17377 | 282 |
KMO,KIAA0355,PTPN6,PRKCD,PTPN21,SETBP1,KIF21B,TNFRSF17,PKIA |
| 3.798e-03 | -5.57 | GSE3337_CTRL_VS_16H_IFNG_IN_CD8POS_DC_UP | MSigDB lists | GSE3337_CTRL_VS_16H_IFNG_IN_CD8POS_DC_UP | 189 | 9 | 17377 | 282 |
BDNF,FGR,HEBP1,PRKCD,ATOX1,CEBPA,PRDM1,TMEM37,DBP |
| 3.847e-03 | -5.56 | GSE37605_C57BL6_VS_NOD_FOXP3_FUSION_GFP_TCONV_UP | MSigDB lists | GSE37605_C57BL6_VS_NOD_FOXP3_FUSION_GFP_TCONV_UP | 155 | 8 | 17377 | 282 |
EPCAM,NRN1,TMEM63C,CEBPA,PRKCA,SCAMP1,ARRDC4,GPLD1 |
| 3.847e-03 | -5.56 | GSE21360_SECONDARY_VS_QUATERNARY_MEMORY_CD8_TCELL_DN | MSigDB lists | GSE21360_SECONDARY_VS_QUATERNARY_MEMORY_CD8_TCELL_DN | 155 | 8 | 17377 | 282 |
P4HA1,QSOX1,BNIP3,FGR,PDK1,ARRDC4,EMILIN2,HK2 |
| 3.849e-03 | -5.56 | TGTTTAC,MIR-30A-5P,MIR-30C,MIR-30D,MIR-30B,MIR-30E-5P | MSigDB lists | TGTTTAC,MIR-30A-5P,MIR-30C,MIR-30D,MIR-30B,MIR-30E-5P | 549 | 18 | 17377 | 282 |
ACVR1,RUNX2,SCAMP1,CAPN5,BNIP3L,EFNA3,SATB2,PRDM1,RAB38,PFN2,FHOD3,ADAMTS3,KIAA0355,GNAO1,KIAA0408,TMOD2,PDE4D,RNF122 |
| 3.850e-03 | -5.56 | RICKMAN_HEAD_AND_NECK_CANCER_A | MSigDB lists | RICKMAN_HEAD_AND_NECK_CANCER_A | 92 | 6 | 17377 | 282 |
NLGN4X,IL17RD,SHISA2,DLX2,MOXD1,CENPV |
| 3.850e-03 | -5.56 | MENSE_HYPOXIA_UP | MSigDB lists | MENSE_HYPOXIA_UP | 92 | 6 | 17377 | 282 |
P4HA1,BNIP3,MXI1,PDK1,HK2,BNIP3L |
| 3.920e-03 | -5.54 | GNF2_MAPT | MSigDB lists | GNF2_MAPT | 40 | 4 | 17377 | 282 |
KIF5C,STXBP1,DYNC1I1,GNAO1 |
| 3.920e-03 | -5.54 | LUI_THYROID_CANCER_CLUSTER_2 | MSigDB lists | LUI_THYROID_CANCER_CLUSTER_2 | 40 | 4 | 17377 | 282 |
KIF5C,WWC1,WFS1,BNIP3L |
| 3.929e-03 | -5.54 | REACTOME_SIGNALING_BY_HIPPO | MSigDB lists | REACTOME_SIGNALING_BY_HIPPO | 20 | 3 | 17377 | 282 |
WWC1,SAV1,WWTR1 |
| 3.929e-03 | -5.54 | DAVICIONI_PAX_FOXO1_SIGNATURE_IN_ARMS_DN | MSigDB lists | DAVICIONI_PAX_FOXO1_SIGNATURE_IN_ARMS_DN | 20 | 3 | 17377 | 282 |
MOXD1,PLK2,PKIA |
| 3.932e-03 | -5.54 | GSE24142_ADULT_VS_FETAL_DN2_THYMOCYTE_UP | MSigDB lists | GSE24142_ADULT_VS_FETAL_DN2_THYMOCYTE_UP | 190 | 9 | 17377 | 282 |
RASL11B,MXI1,DBP,RAB38,ITPR2,SLC30A4,KMO,MPP1,CYP4V2 |
| 3.932e-03 | -5.54 | GSE21379_TFH_VS_NON_TFH_CD4_TCELL_DN | MSigDB lists | GSE21379_TFH_VS_NON_TFH_CD4_TCELL_DN | 190 | 9 | 17377 | 282 |
KCTD15,NECAB2,CYP2J2,EXOC6B,PLEKHG1,ARHGAP28,SLC2A13,HERC6,GPLD1 |
| 3.932e-03 | -5.54 | GSE7460_FOXP3_MUT_VS_HET_ACT_TCONV_DN | MSigDB lists | GSE7460_FOXP3_MUT_VS_HET_ACT_TCONV_DN | 190 | 9 | 17377 | 282 |
LONRF1,RASD2,ZNF521,ZDHHC23,SATB2,NRN1,PRKCA,SAV1,TBC1D8 |
| 3.932e-03 | -5.54 | GSE3982_DC_VS_NKCELL_UP | MSigDB lists | GSE3982_DC_VS_NKCELL_UP | 190 | 9 | 17377 | 282 |
TMEM53,KMO,NDRG2,SGK1,TNS1,IQSEC2,ABHD6,STXBP1,TBC1D8 |
| 3.939e-03 | -5.54 | PTK2 (protein tyrosine kinase 2) | protein interactions | 5747 | 152 | 8 | 17029 | 283 |
ARHGAP26,FGR,GAPDH,PXN,DOCK1,PTPN6,TNS1,NEO1 |
| 3.950e-03 | -5.53 | INHBC (inhibin subunit beta C) | protein interactions | 3626 | 6 | 2 | 17029 | 283 |
ACVR2B,ACVR1 |
| 3.950e-03 | -5.53 | CCDC153 (coiled-coil domain containing 153) | protein interactions | 283152 | 6 | 2 | 17029 | 283 |
NECAB2,DDIT3 |
| 3.950e-03 | -5.53 | Rdx (radixin) | protein interactions | 19684 | 6 | 2 | 17029 | 283 |
CPNE2,ABCC2 |
| 3.980e-03 | -5.53 | chondroblastoma | COSMIC cancer mutations | chondroblastoma | 553 | 18 | 17385 | 281 |
ARHGAP26,ACSL1,ADCY1,RHPN2,RAB38,PALLD,B4GALNT3,HMCN1,FHOD3,CTIF,FKBP9,RASGRF2,LRRIQ3,ZNF521,ARHGAP28,TLN2,TSHR,COBL |
| 4.000e-03 | -5.52 | GSE11057_EFF_MEM_VS_CENT_MEM_CD4_TCELL_DN | MSigDB lists | GSE11057_EFF_MEM_VS_CENT_MEM_CD4_TCELL_DN | 156 | 8 | 17377 | 282 |
PDK1,KLHL3,GPR155,CCDC110,ABCC2,RNF122,APBA2,MTUS1 |
| 4.052e-03 | -5.51 | ruffle | cellular component | GO:0001726 | 165 | 8 | 18223 | 280 |
EPB41L5,FGR,SPATA13,WWC1,PLEKHA1,PALLD,TLN2,COBL |
| 4.057e-03 | -5.51 | GO_IRON_ION_HOMEOSTASIS | MSigDB lists | GO_IRON_ION_HOMEOSTASIS | 65 | 5 | 17377 | 282 |
SLC25A28,SLC40A1,SFXN4,MYC,NEO1 |
| 4.057e-03 | -5.51 | MCMURRAY_TP53_HRAS_COOPERATION_RESPONSE_DN | MSigDB lists | MCMURRAY_TP53_HRAS_COOPERATION_RESPONSE_DN | 65 | 5 | 17377 | 282 |
ABAT,PMAIP1,SATB1,FHOD3,MTUS1 |
| 4.062e-03 | -5.51 | V$RORA1_01 | MSigDB lists | V$RORA1_01 | 227 | 10 | 17377 | 282 |
DACT1,ERN1,EFNA3,NDRG2,STRADB,ABAT,DBP,SATB1,GPR161,NEO1 |
| 4.068e-03 | -5.50 | Signaling events mediated by focal adhesion kinase | Pathway Interaction DB | fak_pathway | 54 | 5 | 2226 | 45 |
ARHGAP26,PXN,ARHGEF11,DOCK1,PTPN21 |
| 4.070e-03 | -5.50 | GSE13306_TREG_VS_TCONV_LAMINA_PROPRIA_UP | MSigDB lists | GSE13306_TREG_VS_TCONV_LAMINA_PROPRIA_UP | 191 | 9 | 17377 | 282 |
MPP1,CAPN5,NDRG2,SGK1,KIAA0513,SHISA2,NRN1,DISP1,GPLD1 |
| 4.113e-03 | -5.49 | platelet aggregation | biological process | GO:0070527 | 42 | 4 | 17256 | 270 |
GAS6,STXBP1,UBASH3B,PTPN6 |
| 4.113e-03 | -5.49 | pyruvate biosynthetic process | biological process | GO:0042866 | 42 | 4 | 17256 | 270 |
GAPDH,ALDOA,OGDHL,HK2 |
| 4.118e-03 | -5.49 | Binding of TCF/LEF:CTNNB1 to target gene promoters | REACTOME pathways | R-HSA-4411364 | 7 | 2 | 10287 | 148 |
TCF7L1,MYC |
| 4.118e-03 | -5.49 | phosphorus metabolic process | biological process | GO:0006793 | 2148 | 49 | 17256 | 270 |
ACSL1,ACVR1,DUSP8,RASAL2,UBASH3B,PTPN21,GAS6,PRKCA,ABHD6,ABHD4,PPM1E,KMO,RPS6KL1,MYC,PRKCD,SGK1,DAB2IP,PDE4D,EPHB6,SMPDL3A,PARP9,IL17RD,GAPDH,PDK1,MPP1,PTPN6,NUAK2,OGDHL,ADCY1,STRADB,WNT11,PXYLP1,ACVR2B,PLEKHA1,LHPP,SGK2,GRK3,NT5DC2,GPLD1,DYRK1B,TRIB3,FGR,PLK2,RASGRF2,MAP2K6,ALDOA,ERN1,HK2,MAPK13 |
| 4.128e-03 | -5.49 | liver | COSMIC cancer mutations | liver | 16606 | 277 | 17385 | 281 |
ARHGAP26,ACVR1,DUSP8,LGR4,RECK,LSM11,ALG1L,CEBPA,PRKCA,ABHD6,NCS1,EPDR1,PMAIP1,CFHR1,TMEM37,TSHR,TBC1D8,KLHL23,KLHL3,WISP3,EXOC6B,DSTN,BNIP3L,SLC25A28,ABCC2,TNS1,ACVR2B,SAV1,SPATA9,PLK2,RASGRF2,ALDOA,ARHGAP28,MAPK13,TMOD2,TANC2,SCN5A,TMEM63C,ZHX3,CYP2J2,SLC36A4,TNFRSF10C,DYNC1I1,HPCAL4,NIPSNAP3B,MTUS1,IL17D,RALGPS2,MYC,ZIC5,SRGAP1,MOXD1,STXBP1,GPR161,EPB41L5,BDNF,QSOX1,SHISA2,ARRDC4,OR11H4,ZNF558,ADAMTS3,ISM1,LRRIQ3,QPCTL,EMILIN2,CLMN,IQSEC2,SMYD3,ZNF516,RASAL2,ST14,FAM131C,C4A,CCDC110,PLXNA2,COLEC10,TIAM2,TMEM53,ZNF827,KMO,DACT1,DAB2IP,PJA1,PDE4D,RAB27B,DNAH5,ATP6AP1L,C3orf67,DZANK1,GAPDH,PDK1,SOX21,CYB5R2,SFXN4,ADCY1,NLGN4X,SATB2,WNT11,RAB38,TBC1D16,TRIQK,IQCK,WFS1,WWTR1,PLEKHG1,P4HA1,TNFSF15,DBP,KLHL31,COBL,KCTD1,C2orf88,CCDC148,MXI1,TMEM132C,BACE1,BIK,CCNJL,KIF5C,ARL2,ZNF219,NEO1,RGS17,GPR155,SMPDL3A,PARP9,TMC7,MN1,B9D1,SLC40A1,PXN,MPP1,GPR137C,GPLD1,TRIB3,FGR,GNAO1,MYOM2,TNFRSF17,DDIT3,B4GALT7,PHC1,CCDC126,ACSL1,HEBP1,PTPN21,NDRG2,NRN1,ABAT,ITPR2,SLC2A13,CACNB4,ABHD4,HMCN1,EPCAM,PPM1E,FKBP9,CPNE2,MARVELD2,DLX6,TMEM143,TLN2,FANK1,OR2W3,ZNF391,PGBD5,PNRC1,CAPN5,ATOX1,TTC22,PLEKHA1,SGK2,NT5DC2,PLEKHB1,DYRK1B,SPNS1,TCF7L1,ERN1,DLX2,APBA2,GPR63,LONRF1,RGS16,RUNX2,ZNF395,BVES,SCART1,FBXO4,UBASH3B,CYP4V2,ATP6V1E2,RASL11B,SETBP1,CHADL,SATB1,PFN2,FHOD3,NUMBL,SLC30A4,GAN,EBF4,BNIP3,NCEH1,VGLL4,BARX1,IL17RD,SPATA13,EFNA3,MAFB,STRADB,WWC1,WDR25,PPFIA4,LHPP,PRDM1,B4GALNT3,KIAA0355,HK2,RNF122,DOCK1,RHPN2,FAM198B,KIF21B,RADIL,CBLN1,KCTD15,RPS6KL1,ZDHHC23,EEPD1,ZNF521,MAP7,MYH15,TMEM120B,HSPA2,FAM78B,PHLDB2,UROS,SLC39A8,PTPN6,JAM3,CENPV,IFT81,LMLN,ANKRD31,RBPMS2,DISP1,NECAB2,PRSS16,ARHGEF11,BLVRB,OVOL2,PRKCD,RASD2,EHD3,GTF2F2,ACTA2,PRICKLE2,TRIM3,SGK1,CCDC122,KIAA0408,MSX1,NUAK2,OGDHL,EXOG,PALLD,TLR6,CTIF,RERE,FMO4,MAP2K6,KIAA0513,ZNF474,THAP10,RNF157,PKIA |
| 4.179e-03 | -5.48 | signal transduction | biological process | GO:0007165 | 4964 | 98 | 17256 | 270 |
ARHGAP26,ZNF516,ACVR1,ACSL1,LGR4,RASAL2,DOCK1,HEBP1,PLXNA2,RHPN2,NDRG2,CEBPA,ITPR2,PRKCA,RADIL,TIAM2,NCS1,EPCAM,PMAIP1,DACT1,RPS6KL1,DAB2IP,EPHB6,PDE4D,RAB27B,TSHR,OR2W3,PDK1,WISP3,PTPN6,CAPN5,ADCY1,BNIP3L,WNT11,ACVR2B,RAB38,PLEKHA1,SGK2,SAV1,GRK3,PLEKHB1,SPNS1,TCF7L1,RASGRF2,PLK2,WFS1,WWTR1,ERN1,ARHGAP28,TNFSF15,MAPK13,DISP1,GPR63,RGS16,RUNX2,ARHGEF11,UBASH3B,ATP6V1E2,RASL11B,GAS6,TNFRSF10C,ZNF219,HPCAL4,NEO1,NUMBL,RALGPS2,GPR155,MYC,RASD2,PRKCD,GTF2F2,SRGAP1,SGK1,PRICKLE2,INAVA,BNIP3,GPR161,B9D1,BDNF,IL17RD,MSX1,PXN,MPP1,EFNA3,NUAK2,WWC1,STRADB,GAREM1,ARRDC4,OR11H4,TLR6,GPLD1,TRIB3,FGR,MAP2K6,GNAO1,TNFRSF17,DDIT3 |
| 4.185e-03 | -5.48 | Ser/Thr_kinase_AS | interpro domains | IPR008271 | 308 | 12 | 18492 | 296 |
DYRK1B,ACVR1,MAP2K6,PLK2,PRKCD,ERN1,NUAK2,SGK1,ACVR2B,PRKCA,SGK2,GRK3 |
| 4.189e-03 | -5.48 | GO_MUSCLE_CONTRACTION | MSigDB lists | GO_MUSCLE_CONTRACTION | 228 | 10 | 17377 | 282 |
SCN5A,PXN,ARHGEF11,MAP2K6,GNAO1,ALDOA,ACTA2,TMOD2,MYOM2,PDE4D |
| 4.194e-03 | -5.47 | GSK3B (glycogen synthase kinase 3 beta) | protein interactions | 2932 | 297 | 12 | 17029 | 283 |
GAPDH,PXN,PMAIP1,ARHGEF11,MPP1,MYC,PRKCD,SGK1,CEBPA,PDE4D,PRKCA,DYNC1I1 |
| 4.199e-03 | -5.47 | SNTB1 (syntrophin beta 1) | protein interactions | 6641 | 20 | 3 | 17029 | 283 |
SCN5A,TNS1,SAV1 |
| 4.204e-03 | -5.47 | voltage-gated calcium channel complex | cellular component | GO:0005891 | 43 | 4 | 18223 | 280 |
CATSPERE,PDE4D,CACNB4,HSPA2 |
| 4.211e-03 | -5.47 | GSE24142_EARLY_THYMIC_PROGENITOR_VS_DN3_THYMOCYTE_FETAL_DN | MSigDB lists | GSE24142_EARLY_THYMIC_PROGENITOR_VS_DN3_THYMOCYTE_FETAL_DN | 192 | 9 | 17377 | 282 |
MPP1,CYP2J2,EHD3,NDRG2,ITPR2,DBP,TMEM120B,SATB1,CBLN1 |
| 4.241e-03 | -5.46 | MODULE_37 | MSigDB lists | MODULE_37 | 426 | 15 | 17377 | 282 |
SPNS1,QSOX1,ACVR1,RALGPS2,SOX21,ALDOA,PLEKHG1,NDRG2,WDR25,LHPP,PRDM1,PDE4D,SAV1,PKIA,RERE |
| 4.254e-03 | -5.46 | prostate-adenoma | COSMIC cancer mutations | prostate-adenoma | 1665 | 41 | 17385 | 281 |
RASAL2,CYP2J2,PTPN21,SETBP1,PRKCA,HMCN1,TIAM2,FHOD3,RGS17,RALGPS2,KMO,PRKCD,ZNF521,SRGAP1,ZDHHC23,EEPD1,NCEH1,RAB27B,DNAH5,STXBP1,TSHR,TMC7,PHLDB2,KLHL3,KLHL23,SLC39A8,ADCY1,NUAK2,TNS1,ABCC2,WNT11,TLR6,GPLD1,IQCK,TCF7L1,LMLN,PLEKHG1,MYOM2,IQSEC2,APBA2,KCTD1 |
| 4.258e-03 | -5.46 | HSP90AA1 (heat shock protein 90 alpha family class A member 1) | protein interactions | 3320 | 806 | 24 | 17029 | 283 |
GAPDH,KLHL23,FBXO4,UBASH3B,NUAK2,PRDM1,ACVR2B,HERC6,PRKCA,SGK2,DYRK1B,FGR,DLX6,MYC,RPS6KL1,ALDOA,PRKCD,ERN1,HK2,GAN,SGK1,EPHB6,HSPA2,SMYD3 |
| 4.264e-03 | -5.46 | ZBTB17 (zinc finger and BTB domain containing 17) | protein interactions | 7709 | 40 | 4 | 17029 | 283 |
PMAIP1,DACT1,MYC,HK2 |
| 4.306e-03 | -5.45 | GO_ION_HOMEOSTASIS | MSigDB lists | GO_ION_HOMEOSTASIS | 555 | 18 | 17377 | 282 |
SLC40A1,KLHL3,SLC39A8,SFXN4,ATOX1,ATP6V1E2,SLC25A28,ABCC2,RAB38,ITPR2,SGK2,CACNB4,NEO1,SLC30A4,WFS1,MYC,SGK1,DDIT3 |
| 4.319e-03 | -5.44 | GO_PROTEIN_PHOSPHORYLATION | MSigDB lists | GO_PROTEIN_PHOSPHORYLATION | 920 | 26 | 17377 | 282 |
IL17RD,ACVR1,PDK1,RASAL2,PTPN6,NUAK2,STRADB,WNT11,ACVR2B,GAS6,PRKCA,SGK2,DYRK1B,TRIB3,FGR,MAP2K6,MYC,RASGRF2,PLK2,RPS6KL1,PRKCD,ERN1,SGK1,MAPK13,DAB2IP,EPHB6 |
| 4.319e-03 | -5.44 | BROWNE_HCMV_INFECTION_20HR_UP | MSigDB lists | BROWNE_HCMV_INFECTION_20HR_UP | 229 | 10 | 17377 | 282 |
MSX1,DUSP8,ADAMTS3,PTPN21,WWC1,KIF5C,ABAT,DLX2,HSPA2,ZNF391 |
| 4.333e-03 | -5.44 | cell junction organization | biological process | GO:0034330 | 200 | 9 | 17256 | 270 |
NUMBL,MARVELD2,ARL2,INAVA,NLGN4X,TNS1,WNT11,PRKCA,TLN2 |
| 4.356e-03 | -5.44 | GSE40274_LEF1_VS_FOXP3_AND_LEF1_TRANSDUCED_ACTIVATED_CD4_TCELL_UP | MSigDB lists | GSE40274_LEF1_VS_FOXP3_AND_LEF1_TRANSDUCED_ACTIVATED_CD4_TCELL_UP | 193 | 9 | 17377 | 282 |
LONRF1,RECK,CYP4V2,SPATA13,KIF5C,DAB2IP,SAV1,SMPDL3A,GPLD1 |
| 4.412e-03 | -5.42 | oesophagus | COSMIC cancer mutations | oesophagus | 15441 | 263 | 17385 | 281 |
ARHGAP26,ACVR1,DUSP8,LGR4,RECK,LSM11,ALG1L,PRKCA,ABHD6,NCS1,EPDR1,PMAIP1,CFHR1,TSHR,TBC1D8,KLHL23,KLHL3,WISP3,EXOC6B,DSTN,SLC25A28,ABCC2,TNS1,ACVR2B,SAV1,SPATA9,PLK2,RASGRF2,ALDOA,ARHGAP28,MAPK13,TMOD2,TANC2,SCN5A,TMEM63C,ZHX3,CYP2J2,SLC36A4,TNFRSF10C,DYNC1I1,HPCAL4,NIPSNAP3B,MTUS1,IL17D,RALGPS2,MYC,ZIC5,SRGAP1,MOXD1,STXBP1,GPR161,EPB41L5,BDNF,QSOX1,SHISA2,ARRDC4,OR11H4,ZNF558,ADAMTS3,ISM1,LRRIQ3,QPCTL,EMILIN2,CLMN,IQSEC2,SMYD3,ZNF516,RASAL2,ST14,C4A,FAM131C,CCDC110,PLXNA2,COLEC10,TIAM2,TMEM53,ZNF827,KMO,DACT1,DAB2IP,PJA1,PDE4D,RAB27B,DNAH5,ATP6AP1L,C3orf67,DZANK1,PDK1,SOX21,CYB5R2,SFXN4,ADCY1,NLGN4X,SATB2,WNT11,RAB38,TBC1D16,TRIQK,IQCK,WFS1,WWTR1,PLEKHG1,P4HA1,TNFSF15,DBP,KLHL31,COBL,C2orf88,CCDC148,MXI1,TMEM132C,BACE1,BIK,CCNJL,KIF5C,ARL2,ZNF219,NEO1,RGS17,GPR155,SMPDL3A,PARP9,TMC7,MN1,B9D1,SLC40A1,MPP1,GPR137C,GPLD1,TRIB3,FGR,GNAO1,MYOM2,TNFRSF17,DDIT3,B4GALT7,PHC1,CCDC126,ACSL1,HEBP1,PTPN21,NDRG2,NRN1,ABAT,ITPR2,SLC2A13,CACNB4,ABHD4,HMCN1,EPCAM,PPM1E,FKBP9,CPNE2,MARVELD2,DLX6,TMEM143,TLN2,FANK1,OR2W3,ZNF391,PGBD5,CAPN5,TTC22,PLEKHA1,SGK2,PLEKHB1,NT5DC2,DYRK1B,SPNS1,TCF7L1,ERN1,DLX2,APBA2,GPR63,LONRF1,RUNX2,ZNF395,BVES,SCART1,UBASH3B,CYP4V2,ATP6V1E2,RASL11B,SETBP1,CHADL,SATB1,PFN2,FHOD3,NUMBL,SLC30A4,GAN,EBF4,BNIP3,NCEH1,VGLL4,IL17RD,SPATA13,EFNA3,MAFB,STRADB,WWC1,WDR25,PPFIA4,LHPP,PRDM1,B4GALNT3,KIAA0355,HK2,RNF122,DOCK1,RHPN2,FAM198B,KIF21B,RADIL,CBLN1,KCTD15,RPS6KL1,EEPD1,ZDHHC23,ZNF521,MAP7,MYH15,TMEM120B,HSPA2,FAM78B,PHLDB2,UROS,PTPN6,SLC39A8,JAM3,IFT81,LMLN,ANKRD31,RBPMS2,DISP1,NECAB2,PRSS16,ARHGEF11,BLVRB,OVOL2,RASD2,EHD3,PRKCD,GTF2F2,SGK1,PRICKLE2,TRIM3,CCDC122,ACTA2,KIAA0408,MSX1,NUAK2,OGDHL,PALLD,TLR6,CTIF,RERE,FMO4,MAP2K6,KIAA0513,ZNF474,RNF157,PKIA |
| 4.453e-03 | -5.41 | WINTER_HYPOXIA_METAGENE | MSigDB lists | WINTER_HYPOXIA_METAGENE | 230 | 10 | 17377 | 282 |
QSOX1,MXI1,GAPDH,ALDOA,BIK,HK2,BNIP3L,P4HA1,BNIP3,DDIT3 |
| 4.453e-03 | -5.41 | V$CEBPA_01 | MSigDB lists | V$CEBPA_01 | 230 | 10 | 17377 | 282 |
BDNF,TCF7L1,MXI1,RASAL2,MAP2K6,PRDM1,PDE4D,ARRDC4,COLEC10,TBC1D16 |
| 4.495e-03 | -5.40 | NAD metabolic process | biological process | GO:0019674 | 69 | 5 | 17256 | 270 |
GAPDH,KMO,ALDOA,PARP9,HK2 |
| 4.507e-03 | -5.40 | GO_PROTEIN_STABILIZATION | MSigDB lists | GO_PROTEIN_STABILIZATION | 126 | 7 | 17377 | 282 |
MSX1,GAPDH,SAV1,PFN2,STXBP1,WFS1,PRKCD |
| 4.507e-03 | -5.40 | MODULE_248 | MSigDB lists | MODULE_248 | 126 | 7 | 17377 | 282 |
RGS16,FGR,PRKCA,ARHGEF11,MPP1,PTPN6,WFS1 |
| 4.526e-03 | -5.40 | GO_PHOSPHATE_CONTAINING_COMPOUND_METABOLIC_PROCESS | MSigDB lists | GO_PHOSPHATE_CONTAINING_COMPOUND_METABOLIC_PROCESS | 1870 | 45 | 17377 | 282 |
ACVR1,RASAL2,DUSP8,UBASH3B,PTPN21,GAS6,PRKCA,CACNB4,ABHD4,ABHD6,PPM1E,KMO,RPS6KL1,MYC,PRKCD,SGK1,DAB2IP,EPHB6,PDE4D,SMPDL3A,IL17RD,GAPDH,PDK1,MPP1,PTPN6,OGDHL,ADCY1,NUAK2,STRADB,WNT11,LHPP,ACVR2B,SGK2,NT5DC2,GPLD1,DYRK1B,TRIB3,FGR,MAP2K6,RASGRF2,PLK2,ERN1,ALDOA,HK2,MAPK13 |
| 4.529e-03 | -5.40 | CEBALLOS_TARGETS_OF_TP53_AND_MYC_UP | MSigDB lists | CEBALLOS_TARGETS_OF_TP53_AND_MYC_UP | 21 | 3 | 17377 | 282 |
ACSL1,HSPA2,MYC |
| 4.529e-03 | -5.40 | PARK_TRETINOIN_RESPONSE_AND_RARA_PLZF_FUSION | MSigDB lists | PARK_TRETINOIN_RESPONSE_AND_RARA_PLZF_FUSION | 21 | 3 | 17377 | 282 |
CEBPA,FGR,PTPN6 |
| 4.529e-03 | -5.40 | AGTCTAG,MIR-151 | MSigDB lists | AGTCTAG,MIR-151 | 21 | 3 | 17377 | 282 |
RHPN2,CACNB4,HPCAL4 |
| 4.529e-03 | -5.40 | GO_REGULATION_OF_MITOCHONDRIAL_MEMBRANE_PERMEABILITY_INVOLVED_IN_APOPTOTIC_PROCESS | MSigDB lists | GO_REGULATION_OF_MITOCHONDRIAL_MEMBRANE_PERMEABILITY_INVOLVED_IN_APOPTOTIC_PROCESS | 21 | 3 | 17377 | 282 |
BNIP3,PMAIP1,BNIP3L |
| 4.591e-03 | -5.38 | protein serine/threonine/tyrosine kinase activity | molecular function | GO:0004712 | 42 | 4 | 17224 | 278 |
SGK1,DYRK1B,ACVR2B,MAP2K6 |
| 4.639e-03 | -5.37 | FARMER_BREAST_CANCER_APOCRINE_VS_LUMINAL | MSigDB lists | FARMER_BREAST_CANCER_APOCRINE_VS_LUMINAL | 308 | 12 | 17377 | 282 |
QSOX1,ACSL1,PMAIP1,KMO,CYP2J2,MAP2K6,P4HA1,BNIP3,RAB38,PLEKHB1,SMPDL3A,MTUS1 |
| 4.657e-03 | -5.37 | MARTORIATI_MDM4_TARGETS_NEUROEPITHELIUM_UP | MSigDB lists | MARTORIATI_MDM4_TARGETS_NEUROEPITHELIUM_UP | 160 | 8 | 17377 | 282 |
CPNE2,PMAIP1,PLK2,MYC,ALDOA,HK2,P4HA1,BNIP3 |
| 4.657e-03 | -5.37 | GSE32986_UNSTIM_VS_GMCSF_AND_CURDLAN_HIGHDOSE_STIM_DC_DN | MSigDB lists | GSE32986_UNSTIM_VS_GMCSF_AND_CURDLAN_HIGHDOSE_STIM_DC_DN | 160 | 8 | 17377 | 282 |
NDRG2,MAPK13,DISP1,PNRC1,UROS,PRKCA,EXOC6B,CYP4V2 |
| 4.657e-03 | -5.37 | GSE16385_UNTREATED_VS_12H_IL4_TREATED_MACROPHAGE_UP | MSigDB lists | GSE16385_UNTREATED_VS_12H_IL4_TREATED_MACROPHAGE_UP | 195 | 9 | 17377 | 282 |
WISP3,DLX6,RBPMS2,ERN1,MYOM2,NRN1,PRKCA,STXBP1,ABHD4 |
| 4.667e-03 | -5.37 | testis | COSMIC cancer mutations | testis | 742 | 22 | 17385 | 281 |
ACVR1,PDK1,NUAK2,PLXNA2,SETBP1,RHPN2,STRADB,ACVR2B,SGK2,PRKCA,TBC1D16,DYRK1B,PPM1E,TRIB3,FGR,PLK2,RPS6KL1,MAP2K6,PRKCD,ERN1,SGK1,MAPK13 |
| 4.681e-03 | -5.36 | GO_NEGATIVE_REGULATION_OF_ACTIN_FILAMENT_POLYMERIZATION | MSigDB lists | GO_NEGATIVE_REGULATION_OF_ACTIN_FILAMENT_POLYMERIZATION | 42 | 4 | 17377 | 282 |
TMOD2,PFN2,PRKCD,FHOD3 |
| 4.681e-03 | -5.36 | mitochondrial outer membrane permeabilization involved in programmed cell death | biological process | GO:1902686 | 22 | 3 | 17256 | 270 |
BNIP3,PMAIP1,BNIP3L |
| 4.764e-03 | -5.35 | GO_REGULATION_OF_PROTEIN_COMPLEX_ASSEMBLY | MSigDB lists | GO_REGULATION_OF_PROTEIN_COMPLEX_ASSEMBLY | 349 | 13 | 17377 | 282 |
PMAIP1,DACT1,PRKCD,BIK,GTF2F2,ARL2,SGK1,DAB2IP,TMOD2,STXBP1,PFN2,TLR6,FHOD3 |
| 4.776e-03 | -5.34 | CHICAS_RB1_TARGETS_CONFLUENT | MSigDB lists | CHICAS_RB1_TARGETS_CONFLUENT | 517 | 17 | 17377 | 282 |
MN1,IL17RD,PXN,BLVRB,FAM198B,ABAT,GAS6,EXOG,PALLD,NT5DC2,FHOD3,MTUS1,FKBP9,RGS17,ACTA2,MOXD1,PARP9 |
| 4.807e-03 | -5.34 | TGCTGCT,MIR-15A,MIR-16,MIR-15B,MIR-195,MIR-424,MIR-497 | MSigDB lists | TGCTGCT,MIR-15A,MIR-16,MIR-15B,MIR-195,MIR-424,MIR-497 | 561 | 18 | 17377 | 282 |
GPR63,BDNF,ACSL1,ZHX3,RECK,BACE1,PLXNA2,ARL2,STRADB,SATB2,PLEKHA1,DYNC1I1,NCS1,PPM1E,MAP7,SGK1,STXBP1,KCTD1 |
| 4.807e-03 | -5.34 | positive regulation of apoptotic process | biological process | GO:0043065 | 628 | 19 | 17256 | 270 |
MSX1,GAPDH,ARHGEF11,BIK,BNIP3L,WNT11,SAV1,TIAM2,GPLD1,PMAIP1,MAP2K6,MYC,RASGRF2,PRKCD,TNFSF15,BNIP3,DAB2IP,FANK1,DDIT3 |
| 4.814e-03 | -5.34 | activation of protein kinase activity | biological process | GO:0032147 | 321 | 12 | 17256 | 270 |
MAP2K6,PRKCD,ERN1,ADCY1,STRADB,INAVA,TNFSF15,WNT11,DAB2IP,GAS6,ACVR2B,TLR6 |
| 4.816e-03 | -5.34 | CHARAFE_BREAST_CANCER_LUMINAL_VS_MESENCHYMAL_DN | MSigDB lists | CHARAFE_BREAST_CANCER_LUMINAL_VS_MESENCHYMAL_DN | 432 | 15 | 17377 | 282 |
BDNF,CPNE2,PHLDB2,RUNX2,MPP1,UBASH3B,WWTR1,EMILIN2,ACTA2,SGK1,STRADB,PRKCA,CENPV,FHOD3,GPR161 |
| 4.839e-03 | -5.33 | BATF (basic leucine zipper ATF-like transcription factor) | protein interactions | 10538 | 21 | 3 | 17029 | 283 |
CEBPA,DBP,DDIT3 |
| 4.839e-03 | -5.33 | CHD9 (chromodomain helicase DNA binding protein 9) | protein interactions | 80205 | 21 | 3 | 17029 | 283 |
EPB41L5,MYC,PRKCD |
| 4.863e-03 | -5.33 | brainstem development | biological process | GO:0003360 | 7 | 2 | 17256 | 270 |
NLGN4X,SCN5A |
| 4.868e-03 | -5.33 | ADP metabolic process | biological process | GO:0046031 | 44 | 4 | 17256 | 270 |
GAPDH,ALDOA,OGDHL,HK2 |
| 4.868e-03 | -5.33 | mesenchyme morphogenesis | biological process | GO:0072132 | 44 | 4 | 17256 | 270 |
ACTA2,WNT11,MSX1,ACVR1 |
| 4.873e-03 | -5.32 | V$ICSBP_Q6 | MSigDB lists | V$ICSBP_Q6 | 233 | 10 | 17377 | 282 |
MSX1,MXI1,CCDC148,MAP2K6,ZIC5,SATB2,TNFSF15,TNFRSF17,VGLL4,HMCN1 |
| 4.873e-03 | -5.32 | V$PITX2_Q2 | MSigDB lists | V$PITX2_Q2 | 233 | 10 | 17377 | 282 |
MSX1,KCTD15,ACVR1,RASAL2,PLXNA2,NDRG2,PRICKLE2,SLC25A28,PRDM1,RNF122 |
| 4.875e-03 | -5.32 | system development | biological process | GO:0048731 | 4216 | 85 | 17256 | 270 |
ARHGAP26,ZNF516,ACVR1,LGR4,ST14,RECK,PLXNA2,NDRG2,CEBPA,NRN1,ABAT,PRKCA,CBLN1,NCS1,EPCAM,DACT1,DLX6,ZNF521,DAB2IP,MYH15,TSHR,KLHL3,SOX21,PTPN6,ADCY1,NLGN4X,SATB2,WNT11,ACVR2B,PLEKHA1,SAV1,JAM3,DYRK1B,TCF7L1,PLK2,RBPMS2,WFS1,WWTR1,TMOD2,DISP1,DLX2,DBP,APBA2,COBL,SCN5A,RUNX2,BVES,BIK,KIF5C,GAS6,OVOL2,HERC6,SATB1,HPCAL4,FHOD3,MYORG,NEO1,KDM7A,NUMBL,MYC,ZIC5,ACTA2,SGK1,TRIM3,BNIP3,STXBP1,BARX1,B9D1,EPB41L5,BDNF,ENAM,LZTS3,SLC40A1,MSX1,EFNA3,MAFB,PRDM1,PALLD,RERE,GPLD1,GNAO1,HK2,CLMN,MYOM2,DDIT3 |
| 4.899e-03 | -5.32 | G alpha (z) signalling events | REACTOME pathways | R-HSA-418597 | 48 | 4 | 10287 | 148 |
RGS17,PRKCA,PRKCD,ADCY1 |
| 4.990e-03 | -5.30 | FIGUEROA_AML_METHYLATION_CLUSTER_4_UP | MSigDB lists | FIGUEROA_AML_METHYLATION_CLUSTER_4_UP | 97 | 6 | 17377 | 282 |
TANC2,ZNF395,PMAIP1,PFN2,RBPMS2,CENPV |
| 5.012e-03 | -5.30 | CUT | pfam domains | PF02376 | 7 | 2 | 17054 | 271 |
SATB2,SATB1 |
| 5.015e-03 | -5.30 | GSE22045_TREG_VS_TCONV_DN | MSigDB lists | GSE22045_TREG_VS_TCONV_DN | 162 | 8 | 17377 | 282 |
SLC40A1,MXI1,LMLN,IGIP,HEBP1,PDE4D,PRKCA,STXBP1 |
| 5.020e-03 | -5.29 | GO_ACTIVATION_OF_PROTEIN_KINASE_ACTIVITY | MSigDB lists | GO_ACTIVATION_OF_PROTEIN_KINASE_ACTIVITY | 272 | 11 | 17377 | 282 |
MAP2K6,PRKCD,ERN1,ADCY1,STRADB,DAB2IP,WNT11,TNFSF15,ACVR2B,GAS6,TLR6 |
| 5.029e-03 | -5.29 | Ventricular conduction(PMID:21076409) | GWAS genes | Ventricular conduction(PMID:21076409) | 15 | 3 | 2388 | 58 |
SETBP1,SCN5A,PRKCA |
| 5.033e-03 | -5.29 | positive regulation of GTPase activity | biological process | GO:0043547 | 407 | 14 | 17256 | 270 |
ARHGAP26,RGS16,RGS17,RASAL2,ARHGEF11,DOCK1,GNAO1,SRGAP1,ARHGAP28,DAB2IP,WNT11,TBC1D16,TIAM2,TBC1D8 |
| 5.063e-03 | -5.29 | muscle contraction | biological process | GO:0006936 | 243 | 10 | 17256 | 270 |
SCN5A,PXN,ARHGEF11,MAP2K6,GNAO1,ALDOA,ACTA2,TMOD2,MYOM2,PDE4D |
| 5.081e-03 | -5.28 | Retrograde endocannabinoid signaling | KEGG pathways | ko04723 | 101 | 6 | 7161 | 113 |
MAPK13,ITPR2,PRKCA,ABHD6,GNAO1,ADCY1 |
| 5.081e-03 | -5.28 | Retrograde endocannabinoid signaling | KEGG pathways | hsa04723 | 101 | 6 | 7161 | 113 |
MAPK13,ITPR2,PRKCA,ABHD6,GNAO1,ADCY1 |
| 5.085e-03 | -5.28 | Dimeric_a/b-barrel | interpro domains | IPR011008 | 7 | 2 | 18492 | 296 |
NECAB2,NIPSNAP3B |
| 5.085e-03 | -5.28 | CUT_dom | interpro domains | IPR003350 | 7 | 2 | 18492 | 296 |
SATB2,SATB1 |
| 5.099e-03 | -5.28 | RhoGEF | pfam domains | PF00621 | 70 | 5 | 17054 | 271 |
ARHGEF11,RASGRF2,TIAM2,SPATA13,PLEKHG1 |
| 5.116e-03 | -5.28 | lung-carcinoma-non_small_cell_carcinoma | COSMIC cancer mutations | lung-carcinoma-non_small_cell_carcinoma | 5292 | 106 | 17385 | 281 |
ARHGAP26,ACSL1,ACVR1,DUSP8,LGR4,DOCK1,PTPN21,CEBPA,SLC2A13,ITPR2,COLEC10,PRKCA,KIF21B,RADIL,EPDR1,FKBP9,PPM1E,PMAIP1,DACT1,RPS6KL1,ZNF521,PJA1,PDE4D,RAB27B,HSPA2,PGBD5,GAPDH,PNRC1,PDK1,PTPN6,BNIP3L,ADCY1,NLGN4X,SATB2,WNT11,TNS1,PLEKHA1,RAB38,ACVR2B,SGK2,SAV1,PLEKHB1,DYRK1B,ANKRD31,PLK2,RASGRF2,ERN1,ALDOA,TNFSF15,MAPK13,COBL,RGS16,MXI1,RUNX2,ARHGEF11,FBXO4,BIK,CYP4V2,SETBP1,ARL2,TNFRSF10C,GAS6,SATB1,FHOD3,NUMBL,RGS17,RALGPS2,GPR155,MYC,PRKCD,RASD2,SRGAP1,TRIM3,SGK1,BNIP3,MOXD1,TMC7,MSX1,PXN,MPP1,EFNA3,OGDHL,NUAK2,SPATA13,PPFIA4,MAFB,STRADB,PRDM1,TLR6,GPLD1,TRIB3,FGR,KIAA0355,ADAMTS3,GNAO1,FMO4,MAP2K6,HK2,CLMN,KIAA0513,TNFRSF17,IQSEC2,RNF157,RNF122,SMYD3,DDIT3 |
| 5.116e-03 | -5.28 | non_small_cell_carcinoma | COSMIC cancer mutations | non_small_cell_carcinoma | 5292 | 106 | 17385 | 281 |
ARHGAP26,ACSL1,ACVR1,DUSP8,LGR4,DOCK1,PTPN21,CEBPA,SLC2A13,ITPR2,COLEC10,PRKCA,KIF21B,RADIL,EPDR1,FKBP9,PPM1E,PMAIP1,DACT1,RPS6KL1,ZNF521,PJA1,PDE4D,RAB27B,HSPA2,PGBD5,GAPDH,PNRC1,PDK1,PTPN6,BNIP3L,ADCY1,NLGN4X,SATB2,WNT11,TNS1,PLEKHA1,RAB38,ACVR2B,SGK2,SAV1,PLEKHB1,DYRK1B,ANKRD31,PLK2,RASGRF2,ERN1,ALDOA,TNFSF15,MAPK13,COBL,RGS16,MXI1,RUNX2,ARHGEF11,FBXO4,BIK,CYP4V2,SETBP1,ARL2,TNFRSF10C,GAS6,SATB1,FHOD3,NUMBL,RGS17,RALGPS2,GPR155,MYC,PRKCD,RASD2,SRGAP1,TRIM3,SGK1,BNIP3,MOXD1,TMC7,MSX1,PXN,MPP1,EFNA3,OGDHL,NUAK2,SPATA13,PPFIA4,MAFB,STRADB,PRDM1,TLR6,GPLD1,TRIB3,FGR,KIAA0355,ADAMTS3,GNAO1,FMO4,MAP2K6,HK2,CLMN,KIAA0513,TNFRSF17,IQSEC2,RNF157,RNF122,SMYD3,DDIT3 |
| 5.119e-03 | -5.27 | KCTD3 (potassium channel tetramerization domain containing 3) | protein interactions | 51133 | 126 | 7 | 17029 | 283 |
PHLDB2,KCTD15,RALGPS2,RASAL2,TANC2,STXBP1,KCTD1 |
| 5.122e-03 | -5.27 | V$PR_02 | MSigDB lists | V$PR_02 | 129 | 7 | 17377 | 282 |
CCDC126,BDNF,DLX2,PXN,ZNF395,DSTN,RERE |
| 5.135e-03 | -5.27 | negative regulation of kinase activity | biological process | GO:0033673 | 283 | 11 | 17256 | 270 |
TRIB3,PPM1E,DUSP8,PTPN6,UBASH3B,PRKCD,WWTR1,DAB2IP,CEBPA,SMYD3,PKIA |
| 5.147e-03 | -5.27 | regulation of hydrolase activity | biological process | GO:0051336 | 1270 | 32 | 17256 | 270 |
ARHGAP26,RGS16,RASAL2,ARHGEF11,DOCK1,BVES,RECK,C4A,PLXNA2,ARL2,GAS6,TNFRSF10C,DYNC1I1,PFN2,TIAM2,RGS17,PMAIP1,MYC,PRKCD,SRGAP1,DAB2IP,HSPA2,TBC1D8,GAPDH,EFNA3,WNT11,TBC1D16,GPLD1,GNAO1,ERN1,ARHGAP28,TNFSF15 |
| 5.150e-03 | -5.27 | YCATTAA_UNKNOWN | MSigDB lists | YCATTAA_UNKNOWN | 521 | 17 | 17377 | 282 |
ACVR1,LSM11,PLXNA2,SATB2,WNT11,TNS1,PRDM1,SATB1,NEO1,TCF7L1,PPM1E,ZNF827,KCTD15,RASGRF2,ERN1,PDE4D,EPHB6 |
| 5.167e-03 | -5.27 | activin-activated receptor activity | molecular function | GO:0017002 | 7 | 2 | 17224 | 278 |
ACVR2B,ACVR1 |
| 5.182e-03 | -5.26 | GO_REGULATION_OF_NUCLEASE_ACTIVITY | MSigDB lists | GO_REGULATION_OF_NUCLEASE_ACTIVITY | 22 | 3 | 17377 | 282 |
DAB2IP,PRKCD,ERN1 |
| 5.202e-03 | -5.26 | GO_DIVALENT_INORGANIC_CATION_TRANSMEMBRANE_TRANSPORTER_ACTIVITY | MSigDB lists | GO_DIVALENT_INORGANIC_CATION_TRANSMEMBRANE_TRANSPORTER_ACTIVITY | 163 | 8 | 17377 | 282 |
SLC40A1,ITPR2,GAS6,TMEM37,SLC30A4,CACNB4,SLC39A8,NCS1 |
| 5.202e-03 | -5.26 | GSE21927_SPLENIC_C26GM_TUMOROUS_VS_BONE_MARROW_MONOCYTES_DN | MSigDB lists | GSE21927_SPLENIC_C26GM_TUMOROUS_VS_BONE_MARROW_MONOCYTES_DN | 163 | 8 | 17377 | 282 |
ARHGAP26,ZNF521,SGK1,PDE4D,LHPP,ZNF558,GPR161,GPLD1 |
| 5.222e-03 | -5.25 | GROSS_HIF1A_TARGETS_UP | MSigDB lists | GROSS_HIF1A_TARGETS_UP | 7 | 2 | 17377 | 282 |
MAFB,TCF7L1 |
| 5.222e-03 | -5.25 | ACGCACA,MIR-210 | MSigDB lists | ACGCACA,MIR-210 | 7 | 2 | 17377 | 282 |
ZNF827,EFNA3 |
| 5.222e-03 | -5.25 | FARDIN_HYPOXIA_9 | MSigDB lists | FARDIN_HYPOXIA_9 | 7 | 2 | 17377 | 282 |
BNIP3,PDK1 |
| 5.239e-03 | -5.25 | WARTERS_RESPONSE_TO_IR_SKIN | MSigDB lists | WARTERS_RESPONSE_TO_IR_SKIN | 69 | 5 | 17377 | 282 |
CHADL,FAM198B,TNFRSF10C,ZNF219,JAM3 |
| 5.239e-03 | -5.25 | PEDERSEN_TARGETS_OF_611CTF_ISOFORM_OF_ERBB2 | MSigDB lists | PEDERSEN_TARGETS_OF_611CTF_ISOFORM_OF_ERBB2 | 69 | 5 | 17377 | 282 |
PHLDB2,LGR4,CENPV,WWTR1,HK2 |
| 5.239e-03 | -5.25 | PID_VEGFR1_2_PATHWAY | MSigDB lists | PID_VEGFR1_2_PATHWAY | 69 | 5 | 17377 | 282 |
PXN,PRKCA,MAP2K6,PTPN6,PRKCD |
| 5.239e-03 | -5.25 | GGGGCCC,MIR-296 | MSigDB lists | GGGGCCC,MIR-296 | 69 | 5 | 17377 | 282 |
NUMBL,IQSEC2,ZNF219,SOX21,CTIF |
| 5.245e-03 | -5.25 | HELLER_SILENCED_BY_METHYLATION_DN | MSigDB lists | HELLER_SILENCED_BY_METHYLATION_DN | 98 | 6 | 17377 | 282 |
TRIB3,RGS16,TNFRSF17,TSHR,MYC,DDIT3 |
| 5.266e-03 | -5.25 | DH-domain | interpro domains | IPR000219 | 70 | 5 | 18492 | 296 |
ARHGEF11,RASGRF2,TIAM2,SPATA13,PLEKHG1 |
| 5.312e-03 | -5.24 | positive regulation of programmed cell death | biological process | GO:0043068 | 634 | 19 | 17256 | 270 |
MSX1,GAPDH,ARHGEF11,BIK,BNIP3L,WNT11,SAV1,TIAM2,GPLD1,PMAIP1,MAP2K6,MYC,RASGRF2,PRKCD,TNFSF15,BNIP3,DAB2IP,FANK1,DDIT3 |
| 5.342e-03 | -5.23 | CRKL (CRK like proto-oncogene, adaptor protein) | protein interactions | 1399 | 127 | 7 | 17029 | 283 |
GAREM1,EPHB6,PLEKHA1,PXN,PNRC1,DOCK1,BIK |
| 5.362e-03 | -5.23 | pattern specification process | biological process | GO:0007389 | 410 | 14 | 17256 | 270 |
EPB41L5,MSX1,ACVR1,PLXNA2,MAFB,SATB2,DISP1,OVOL2,DLX2,ACVR2B,DNAH5,BARX1,COBL,DDIT3 |
| 5.379e-03 | -5.23 | DUTERTRE_ESTRADIOL_RESPONSE_24HR_DN | MSigDB lists | DUTERTRE_ESTRADIOL_RESPONSE_24HR_DN | 480 | 16 | 17377 | 282 |
EPB41L5,PHLDB2,TCF7L1,ACVR1,PNRC1,PLK2,EXOC6B,WWTR1,NUAK2,KIAA0513,SHISA2,PALLD,RAB27B,ABHD4,DDIT3,PARP9 |
| 5.380e-03 | -5.23 | peptidyl-serine phosphorylation | biological process | GO:0018105 | 170 | 8 | 17256 | 270 |
PLK2,PRKCD,ERN1,SGK1,MAPK13,GAS6,PRKCA,SGK2 |
| 5.394e-03 | -5.22 | DAVICIONI_MOLECULAR_ARMS_VS_ERMS_UP | MSigDB lists | DAVICIONI_MOLECULAR_ARMS_VS_ERMS_UP | 314 | 12 | 17377 | 282 |
ARHGAP26,RGS17,IFT81,SCAMP1,NLGN4X,NRN1,SATB2,ABAT,TMEM120B,COBL,SMPDL3A,PGBD5 |
| 5.400e-03 | -5.22 | negative regulation of cellular process | biological process | GO:0048523 | 4646 | 92 | 17256 | 270 |
ACVR1,DUSP8,LGR4,RASAL2,RECK,C4A,PLXNA2,NDRG2,CEBPA,ITPR2,ABAT,PRKCA,ABHD6,CBLN1,EPCAM,PPM1E,DACT1,DAB2IP,PDE4D,EPHB6,FANK1,HSPA2,PHLDB2,GAPDH,WISP3,PTPN6,BNIP3L,NLGN4X,SATB2,WNT11,ACVR2B,PLEKHA1,SAV1,PLK2,WFS1,RBPMS2,ERN1,WWTR1,ARHGAP28,TMOD2,DLX2,KCTD1,RGS16,RUNX2,NECAB2,MXI1,ZHX3,FBXO4,UBASH3B,RASL11B,CHADL,SLX1B,GAS6,OVOL2,TNFRSF10C,ZNF219,SATB1,PFN2,FHOD3,RGS17,MYC,PRKCD,RASD2,SRGAP1,BNIP3,STXBP1,BARX1,GPR161,PARP9,EPB41L5,SLC40A1,QSOX1,BDNF,MSX1,NUAK2,WWC1,STRADB,MAFB,SHISA2,PRDM1,TLR6,RERE,GPLD1,TRIB3,MAP2K6,HK2,CLMN,SMYD3,B4GALT7,DDIT3,PKIA,PHC1 |
| 5.439e-03 | -5.21 | HuR (ELAVL1) binds and stabilizes mRNA | REACTOME pathways | R-HSA-450520 | 8 | 2 | 10287 | 148 |
PRKCA,PRKCD |
| 5.441e-03 | -5.21 | MODULE_205 | MSigDB lists | MODULE_205 | 275 | 11 | 17377 | 282 |
B9D1,PPM1E,IFT81,MSX1,PRSS16,ZNF395,ST14,EXOC6B,TANC2,TSHR,TIAM2 |
| 5.446e-03 | -5.21 | haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-acute_lymphoblastic_T_cell_leukaemia | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-acute_lymphoblastic_T_cell_leukaemia | 752 | 22 | 17385 | 281 |
MN1,RASAL2,DOCK1,KLHL23,ARHGEF11,PTPN6,ADCY1,SETBP1,CEBPA,PRDM1,DYNC1I1,HMCN1,MTUS1,EPDR1,SLC30A4,ERN1,MAP7,KIAA0513,CLMN,MOXD1,DNAH5,GPR161 |
| 5.446e-03 | -5.21 | acute_lymphoblastic_T_cell_leukaemia | COSMIC cancer mutations | acute_lymphoblastic_T_cell_leukaemia | 752 | 22 | 17385 | 281 |
MN1,RASAL2,DOCK1,KLHL23,ARHGEF11,PTPN6,ADCY1,SETBP1,CEBPA,PRDM1,DYNC1I1,HMCN1,MTUS1,EPDR1,SLC30A4,ERN1,MAP7,KIAA0513,CLMN,MOXD1,DNAH5,GPR161 |
| 5.469e-03 | -5.21 | ENTPD5 (ectonucleoside triphosphate diphosphohydrolase 5) | protein interactions | 957 | 7 | 2 | 17029 | 283 |
MXI1,PRKCA |
| 5.469e-03 | -5.21 | KCNJ1 (potassium voltage-gated channel subfamily J member 1) | protein interactions | 3758 | 7 | 2 | 17029 | 283 |
SGK1,PRKCD |
| 5.469e-03 | -5.21 | Marcks (myristoylated alanine rich protein kinase C substrate) | protein interactions | 17118 | 7 | 2 | 17029 | 283 |
PRKCA,PRKCD |
| 5.476e-03 | -5.21 | cell projection | cellular component | GO:0042995 | 2051 | 46 | 18223 | 280 |
NECAB2,BVES,BACE1,C4A,BLVRB,ARL2,KIF5C,NDRG2,ABAT,KIF21B,PFN2,TIAM2,NCS1,RGS17,EHD3,ACTA2,TRIM3,DAB2IP,BNIP3,EPHB6,TLN2,DNAH5,STXBP1,GPR161,EPB41L5,B9D1,BDNF,PXN,SLC9C1,MPP1,SPATA13,WWC1,NLGN4X,ABCC2,CATSPERE,PLEKHA1,PALLD,OR11H4,IFT81,FGR,PLK2,GNAO1,WFS1,TMOD2,APBA2,COBL |
| 5.481e-03 | -5.21 | positive regulation of cellular component biogenesis | biological process | GO:0044089 | 499 | 16 | 17256 | 270 |
EPB41L5,PHLDB2,BDNF,PPM1E,PXN,PMAIP1,BIK,GTF2F2,ARL2,SLX1B,WNT11,PRKCA,TLR6,PFN2,COBL,CBLN1 |
| 5.483e-03 | -5.21 | MIYAGAWA_TARGETS_OF_EWSR1_ETS_FUSIONS_DN | MSigDB lists | MIYAGAWA_TARGETS_OF_EWSR1_ETS_FUSIONS_DN | 200 | 9 | 17377 | 282 |
QSOX1,RECK,LSM11,PRICKLE2,BNIP3,PRDM1,FAM198B,TANC2,PKIA |
| 5.506e-03 | -5.20 | Axon guidance | REACTOME pathways | R-HSA-422475 | 549 | 16 | 10287 | 148 |
IL17RD,SCN5A,RASAL2,DUSP8,ARHGEF11,DOCK1,PLXNA2,EFNA3,PRKCA,PFN2,CACNB4,NEO1,RASGRF2,SRGAP1,DAB2IP,EPHB6 |
| 5.535e-03 | -5.20 | REACTOME_G_ALPHA_Z_SIGNALLING_EVENTS | MSigDB lists | REACTOME_G_ALPHA_Z_SIGNALLING_EVENTS | 44 | 4 | 17377 | 282 |
RGS17,PRKCA,PRKCD,ADCY1 |
| 5.547e-03 | -5.19 | CUT | prosite domains | PS51042 | 7 | 2 | 12060 | 202 |
SATB2,SATB1 |
| 5.569e-03 | -5.19 | GO_NEGATIVE_REGULATION_OF_NUCLEOCYTOPLASMIC_TRANSPORT | MSigDB lists | GO_NEGATIVE_REGULATION_OF_NUCLEOCYTOPLASMIC_TRANSPORT | 70 | 5 | 17377 | 282 |
DAB2IP,MXI1,GAS6,WWTR1,PKIA |
| 5.588e-03 | -5.19 | HELLER_HDAC_TARGETS_DN | MSigDB lists | HELLER_HDAC_TARGETS_DN | 276 | 11 | 17377 | 282 |
TRIB3,PMAIP1,MYC,EHD3,SETBP1,MYOM2,MAPK13,PDE4D,TNFRSF17,TSHR,DDIT3 |
| 5.592e-03 | -5.19 | DBL_dom_sf | interpro domains | IPR035899 | 71 | 5 | 18492 | 296 |
ARHGEF11,RASGRF2,TIAM2,SPATA13,PLEKHG1 |
| 5.638e-03 | -5.18 | FERM_2 | prosite domains | PS00661 | 22 | 3 | 12060 | 202 |
EPB41L5,TLN2,PTPN21 |
| 5.666e-03 | -5.17 | PEREZ_TP63_TARGETS | MSigDB lists | PEREZ_TP63_TARGETS | 316 | 12 | 17377 | 282 |
EPB41L5,ARHGAP26,ACSL1,SLC39A8,BIK,SPATA13,EFNA3,ADCY1,MAFB,DLX2,MOXD1,ABHD6 |
| 5.677e-03 | -5.17 | embryonic morphogenesis | biological process | GO:0048598 | 546 | 17 | 17256 | 270 |
B9D1,EPB41L5,MSX1,ACVR1,RUNX2,ST14,RECK,MAFB,SATB2,WNT11,ACVR2B,OVOL2,RBPMS2,DACT1,DLX6,DLX2,COBL |
| 5.728e-03 | -5.16 | PROTEIN_KINASE_ST | prosite domains | PS00108 | 308 | 12 | 12060 | 202 |
DYRK1B,ACVR1,MAP2K6,PLK2,PRKCD,ERN1,NUAK2,SGK1,ACVR2B,PRKCA,SGK2,GRK3 |
| 5.755e-03 | -5.16 | regulation of protein binding | biological process | GO:0043393 | 209 | 9 | 17256 | 270 |
EPB41L5,TRIB3,BDNF,DACT1,PLK2,CFHR1,UBASH3B,PRKCD,DAB2IP |
| 5.765e-03 | -5.16 | cell-cell junction organization | biological process | GO:0045216 | 172 | 8 | 17256 | 270 |
NUMBL,MARVELD2,INAVA,NLGN4X,ARL2,WNT11,PRKCA,TLN2 |
| 5.800e-03 | -5.15 | catalytic activity, acting on a glycoprotein | molecular function | GO:0140103 | 23 | 3 | 17224 | 278 |
CCDC126,B4GALNT3,B4GALT7 |
| 5.806e-03 | -5.15 | V$CEBP_Q3 | MSigDB lists | V$CEBP_Q3 | 239 | 10 | 17377 | 282 |
MN1,BDNF,PPM1E,MXI1,MAP2K6,GNAO1,OVOL2,PALLD,DDIT3,GPLD1 |
| 5.843e-03 | -5.14 | V$FOX_Q2 | MSigDB lists | V$FOX_Q2 | 202 | 9 | 17377 | 282 |
PRICKLE2,CEBPA,PRDM1,COLEC10,SLC39A8,GNAO1,HMCN1,ZIC5,NEO1 |
| 5.872e-03 | -5.14 | positive regulation of cellular protein metabolic process | biological process | GO:0032270 | 1542 | 37 | 17256 | 270 |
LONRF1,ACSL1,ACVR1,NECAB2,FBXO4,CEBPA,GAS6,TNFRSF10C,PRKCA,PFN2,PMAIP1,DACT1,MYC,PRKCD,RASD2,INAVA,DAB2IP,EPHB6,HSPA2,PARP9,ADCY1,EFNA3,WWC1,STRADB,WNT11,GAREM1,ACVR2B,ARRDC4,TLR6,GPLD1,TRIB3,WFS1,MAP2K6,PLK2,ERN1,TNFSF15,SMYD3 |
| 5.882e-03 | -5.14 | chordate embryonic development | biological process | GO:0043009 | 548 | 17 | 17256 | 270 |
EPB41L5,B9D1,MSX1,RUNX2,ACVR1,ST14,PLXNA2,SATB2,CEBPA,WNT11,PRDM1,OVOL2,DACT1,DLX2,TANC2,APBA2,COBL |
| 5.889e-03 | -5.13 | OXFORD_RALA_OR_RALB_TARGETS_DN | MSigDB lists | OXFORD_RALA_OR_RALB_TARGETS_DN | 23 | 3 | 17377 | 282 |
TNS1,PALLD,HK2 |
| 5.889e-03 | -5.13 | GROSS_HIF1A_TARGETS_DN | MSigDB lists | GROSS_HIF1A_TARGETS_DN | 23 | 3 | 17377 | 282 |
BNIP3,GAPDH,PDK1 |
| 5.889e-03 | -5.13 | biliary_tract | COSMIC cancer mutations | biliary_tract | 15787 | 267 | 17385 | 281 |
ARHGAP26,ACVR1,DUSP8,LGR4,RECK,LSM11,ALG1L,CEBPA,PRKCA,ABHD6,NCS1,EPDR1,PMAIP1,CFHR1,TMEM37,TSHR,KLHL23,KLHL3,WISP3,EXOC6B,DSTN,BNIP3L,SLC25A28,ABCC2,TNS1,ACVR2B,SAV1,SPATA9,PLK2,RASGRF2,ALDOA,ARHGAP28,MAPK13,TMOD2,TANC2,SCN5A,ZHX3,CYP2J2,SLC36A4,TNFRSF10C,DYNC1I1,HPCAL4,NIPSNAP3B,MTUS1,IL17D,RALGPS2,MYC,ZIC5,SRGAP1,MOXD1,STXBP1,GPR161,EPB41L5,BDNF,QSOX1,SHISA2,ARRDC4,OR11H4,ZNF558,ADAMTS3,ISM1,LRRIQ3,QPCTL,EMILIN2,CLMN,IQSEC2,SMYD3,ZNF516,RASAL2,ST14,FAM131C,CCDC110,PLXNA2,COLEC10,TIAM2,TMEM53,KMO,DACT1,DAB2IP,PJA1,PDE4D,RAB27B,DNAH5,ATP6AP1L,KIAA1549,C3orf67,GAPDH,PDK1,SOX21,CYB5R2,SFXN4,ADCY1,NLGN4X,SATB2,WNT11,RAB38,TBC1D16,IQCK,WFS1,WWTR1,PLEKHG1,P4HA1,TNFSF15,DBP,COBL,KCTD1,C2orf88,CCDC148,MXI1,TMEM132C,BACE1,BIK,CCNJL,KIF5C,GAS6,ZNF219,NEO1,RGS17,GPR155,SMPDL3A,PARP9,TMC7,MN1,B9D1,SLC40A1,PXN,MPP1,GPR137C,GPLD1,TRIB3,FGR,GNAO1,MYOM2,TNFRSF17,DDIT3,B4GALT7,PHC1,CCDC126,ACSL1,HEBP1,PTPN21,NDRG2,NRN1,ABAT,ITPR2,SLC2A13,ABHD4,HMCN1,EPCAM,PPM1E,FKBP9,CPNE2,DLX6,TMEM143,TLN2,FANK1,OR2W3,ZNF391,PGBD5,PNRC1,CAPN5,TTC22,PLEKHA1,SGK2,NT5DC2,PLEKHB1,DYRK1B,SPNS1,TCF7L1,ERN1,DLX2,APBA2,GPR63,LONRF1,RGS16,RUNX2,ZNF395,BVES,FBXO4,UBASH3B,CYP4V2,ATP6V1E2,RASL11B,SETBP1,CHADL,SATB1,PFN2,FHOD3,NUMBL,SLC30A4,GAN,EBF4,BNIP3,NCEH1,VGLL4,BARX1,IL17RD,SPATA13,EFNA3,MAFB,STRADB,WWC1,WDR25,PPFIA4,LHPP,PRDM1,B4GALNT3,KIAA0355,HK2,RNF122,DOCK1,RHPN2,FAM198B,KIF21B,RADIL,CBLN1,KCTD15,RPS6KL1,ZDHHC23,EEPD1,ZNF521,MAP7,MYH15,TMEM120B,HSPA2,FAM78B,PHLDB2,UROS,PTPN6,SLC39A8,JAM3,CENPV,IFT81,LMLN,ANKRD31,RBPMS2,DISP1,NECAB2,PRSS16,ARHGEF11,BLVRB,OVOL2,RASD2,EHD3,PRKCD,GTF2F2,ACTA2,PRICKLE2,TRIM3,SGK1,CCDC122,KIAA0408,MSX1,NUAK2,OGDHL,EXOG,PALLD,TLR6,CTIF,RERE,FMO4,MAP2K6,KIAA0513,ZNF474,THAP10,RNF157,PKIA |
| 5.914e-03 | -5.13 | V$LXR_Q3 | MSigDB lists | V$LXR_Q3 | 71 | 5 | 17377 | 282 |
RASL11B,SGK1,MAFB,HPCAL4,BLVRB |
| 5.916e-03 | -5.13 | ACTGTGA,MIR-27A,MIR-27B | MSigDB lists | ACTGTGA,MIR-27A,MIR-27B | 442 | 15 | 17377 | 282 |
LONRF1,ZNF827,PPM1E,ACVR1,ST14,PLK2,RBPMS2,EHD3,EEPD1,PRICKLE2,SATB2,ARRDC4,APBA2,PKIA,NEO1 |
| 5.916e-03 | -5.13 | MODULE_136 | MSigDB lists | MODULE_136 | 442 | 15 | 17377 | 282 |
SPNS1,MSX1,ACVR1,RALGPS2,SOX21,ALDOA,PLEKHG1,WDR25,LHPP,PRDM1,PDE4D,SAV1,TNFRSF17,PKIA,RERE |
| 5.999e-03 | -5.12 | GO_ADP_METABOLIC_PROCESS | MSigDB lists | GO_ADP_METABOLIC_PROCESS | 45 | 4 | 17377 | 282 |
GAPDH,ALDOA,OGDHL,HK2 |
| 5.999e-03 | -5.12 | GO_CELLULAR_RESPONSE_TO_CALCIUM_ION | MSigDB lists | GO_CELLULAR_RESPONSE_TO_CALCIUM_ION | 45 | 4 | 17377 | 282 |
CPNE2,SCN5A,GPLD1,ADCY1 |
| 5.999e-03 | -5.12 | YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_8 | MSigDB lists | YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_8 | 45 | 4 | 17377 | 282 |
SGK1,WNT11,MYC,HK2 |
| 6.012e-03 | -5.11 | positive regulation of mitochondrial membrane permeability | biological process | GO:0035794 | 24 | 3 | 17256 | 270 |
BNIP3,PMAIP1,BNIP3L |
| 6.012e-03 | -5.11 | regulation of activin receptor signaling pathway | biological process | GO:0032925 | 24 | 3 | 17256 | 270 |
ACVR2B,ACVR1,DACT1 |
| 6.024e-03 | -5.11 | regulation of biological quality | biological process | GO:0065008 | 3779 | 77 | 17256 | 270 |
LGR4,DOCK1,PLXNA2,CEBPA,ITPR2,ABAT,PRKCA,CACNB4,ABHD6,ABHD4,CBLN1,PMAIP1,KMO,DACT1,DAB2IP,PDE4D,TLN2,GAPDH,KLHL3,SLC9C1,SLC39A8,PTPN6,SFXN4,DSTN,ATOX1,BNIP3L,ADCY1,NLGN4X,SLC25A28,ABCC2,ACVR2B,PLEKHA1,RAB38,SAV1,JAM3,PLK2,WFS1,ERN1,ALDOA,ARHGAP28,TMOD2,SCN5A,MXI1,BVES,UBASH3B,FBXO4,ATP6V1E2,ARL2,SLX1B,GAS6,ZNF219,PFN2,FHOD3,NEO1,SLC30A4,MYC,PRKCD,EHD3,ACTA2,SGK1,INAVA,BNIP3,MOXD1,STXBP1,QSOX1,BDNF,LZTS3,SLC40A1,MSX1,MAFB,PPFIA4,TLR6,GPLD1,FGR,HK2,TNFRSF17,DDIT3 |
| 6.038e-03 | -5.11 | KRAS.PROSTATE_UP.V1_DN | MSigDB lists | KRAS.PROSTATE_UP.V1_DN | 133 | 7 | 17377 | 282 |
ARHGAP28,DZANK1,MAFB,EPHB6,COLEC10,SLC30A4,COBL |
| 6.067e-03 | -5.10 | KEGG_GNRH_SIGNALING_PATHWAY | MSigDB lists | KEGG_GNRH_SIGNALING_PATHWAY | 101 | 6 | 17377 | 282 |
MAPK13,ITPR2,PRKCA,MAP2K6,PRKCD,ADCY1 |
| 6.067e-03 | -5.10 | AMBROSINI_FLAVOPIRIDOL_TREATMENT_TP53 | MSigDB lists | AMBROSINI_FLAVOPIRIDOL_TREATMENT_TP53 | 101 | 6 | 17377 | 282 |
KIAA0513,KIF5C,ITPR2,ACSL1,TSHR,NEO1 |
| 6.094e-03 | -5.10 | - | gene3d domains | 2.60.40.150 | 154 | 8 | 8148 | 145 |
CPNE2,RASAL2,DOCK1,PRKCD,CAPN5,WWC1,DAB2IP,PRKCA |
| 6.100e-03 | -5.10 | follicular_lymphoma | COSMIC cancer mutations | follicular_lymphoma | 1243 | 32 | 17385 | 281 |
CCDC148,DOCK1,UBASH3B,SETBP1,ITPR2,PRKCA,RADIL,HMCN1,FHOD3,MTUS1,ZNF827,SLC30A4,KMO,GPR155,ZNF521,EBF4,GAN,GTF2F2,DNAH5,TBC1D8,PGBD5,CAPN5,ADCY1,NLGN4X,SATB2,RAB38,GPR137C,B4GALNT3,ADAMTS3,ISM1,CLMN,COBL |
| 6.147e-03 | -5.09 | V$NRF2_Q4 | MSigDB lists | V$NRF2_Q4 | 241 | 10 | 17377 | 282 |
CCDC126,GAPDH,BLVRB,ALDOA,NDRG2,BNIP3,PRDM1,PDE4D,ABHD4,PFN2 |
| 6.149e-03 | -5.09 | protein modification process | biological process | GO:0036211 | 3147 | 66 | 17256 | 270 |
CCDC126,LONRF1,ACVR1,DUSP8,RASAL2,RECK,C4A,FBXO4,UBASH3B,PTPN21,ALG1L,NRN1,GAS6,HERC6,PRKCA,SATB1,KDM7A,FKBP9,PPM1E,RPS6KL1,MYC,PRKCD,ZDHHC23,GAN,SGK1,TRIM3,DAB2IP,PJA1,EPHB6,PARP9,ENAM,QSOX1,IL17RD,GAPDH,B3GLCT,PDK1,KLHL23,KLHL3,PTPN6,NUAK2,STRADB,WNT11,ACVR2B,LHPP,RAB38,SGK2,ARRDC4,GRK3,GPLD1,DYRK1B,TRIB3,FGR,RASGRF2,PLK2,WFS1,MAP2K6,QPCTL,ERN1,WWTR1,P4HA1,MAPK13,KLHL31,RNF122,SMYD3,B4GALT7,PHC1 |
| 6.149e-03 | -5.09 | cellular protein modification process | biological process | GO:0006464 | 3147 | 66 | 17256 | 270 |
CCDC126,LONRF1,ACVR1,DUSP8,RASAL2,RECK,C4A,FBXO4,UBASH3B,PTPN21,ALG1L,NRN1,GAS6,HERC6,PRKCA,SATB1,KDM7A,FKBP9,PPM1E,RPS6KL1,MYC,PRKCD,ZDHHC23,GAN,SGK1,TRIM3,DAB2IP,PJA1,EPHB6,PARP9,ENAM,QSOX1,IL17RD,GAPDH,B3GLCT,PDK1,KLHL23,KLHL3,PTPN6,NUAK2,STRADB,WNT11,ACVR2B,LHPP,RAB38,SGK2,ARRDC4,GRK3,GPLD1,DYRK1B,TRIB3,FGR,RASGRF2,PLK2,WFS1,MAP2K6,QPCTL,ERN1,WWTR1,P4HA1,MAPK13,KLHL31,RNF122,SMYD3,B4GALT7,PHC1 |
| 6.167e-03 | -5.09 | positive regulation of stress fiber assembly | biological process | GO:0051496 | 47 | 4 | 17256 | 270 |
WNT11,PPM1E,PXN,PFN2 |
| 6.179e-03 | -5.09 | regulation of phosphorylation | biological process | GO:0042325 | 1547 | 37 | 17256 | 270 |
ACSL1,ACVR1,NECAB2,DUSP8,UBASH3B,NDRG2,CEBPA,GAS6,TNFRSF10C,PRKCA,PFN2,PPM1E,DACT1,MYC,PRKCD,INAVA,DAB2IP,PDE4D,EPHB6,HSPA2,PARP9,PTPN6,ADCY1,WWC1,STRADB,WNT11,GAREM1,ACVR2B,TLR6,TRIB3,FGR,MAP2K6,WWTR1,ERN1,TNFSF15,SMYD3,PKIA |
| 6.202e-03 | -5.08 | GO_EMBRYONIC_ORGAN_DEVELOPMENT | MSigDB lists | GO_EMBRYONIC_ORGAN_DEVELOPMENT | 402 | 14 | 17377 | 282 |
MSX1,ACVR1,RUNX2,ST14,DLX6,MAFB,WNT11,CEBPA,SATB2,PRDM1,DLX2,OVOL2,COBL,DDIT3 |
| 6.206e-03 | -5.08 | GO_APOPTOTIC_SIGNALING_PATHWAY | MSigDB lists | GO_APOPTOTIC_SIGNALING_PATHWAY | 280 | 11 | 17377 | 282 |
TRIB3,PDK1,PMAIP1,PRKCD,ERN1,BNIP3L,BNIP3,DAB2IP,TNFRSF10C,PRKCA,DDIT3 |
| 6.221e-03 | -5.08 | SENESE_HDAC1_AND_HDAC2_TARGETS_DN | MSigDB lists | SENESE_HDAC1_AND_HDAC2_TARGETS_DN | 204 | 9 | 17377 | 282 |
MN1,ZNF395,DACT1,DSTN,PRICKLE2,TNS1,TMEM37,ZNF219,MTUS1 |
| 6.229e-03 | -5.08 | oesophagus-lower_third-carcinoma-squamous_cell_carcinoma | COSMIC cancer mutations | oesophagus-lower_third-carcinoma-squamous_cell_carcinoma | 3601 | 76 | 17385 | 281 |
ARHGAP26,ZNF516,RASAL2,FAM131C,PLXNA2,RHPN2,ABAT,COLEC10,ABHD4,CACNB4,RADIL,HMCN1,CPNE2,DLX6,DACT1,ZNF521,MAP7,DAB2IP,MYH15,TLN2,DNAH5,ZNF391,PHLDB2,SFXN4,CAPN5,ADCY1,SATB2,TNS1,SGK2,SPNS1,TCF7L1,PLK2,ERN1,WWTR1,PLEKHG1,P4HA1,DISP1,DBP,TANC2,APBA2,GPR63,C2orf88,CCDC148,ARHGEF11,SCART1,UBASH3B,KIF5C,ATP6V1E2,RASL11B,SETBP1,CHADL,DYNC1I1,MTUS1,GPR155,ZIC5,PRKCD,EHD3,RASD2,GAN,PRICKLE2,MN1,SLC40A1,PPFIA4,STRADB,WDR25,PRDM1,OR11H4,PALLD,GPR137C,KIAA0355,ADAMTS3,ISM1,EMILIN2,QPCTL,CLMN,SMYD3 |
| 6.257e-03 | -5.07 | lymph_node | COSMIC cancer mutations | lymph_node | 1755 | 42 | 17385 | 281 |
CCDC148,ACVR1,DOCK1,ITPR2,PRKCA,HMCN1,FHOD3,NEO1,FKBP9,MYC,RPS6KL1,ZNF521,SGK1,PRICKLE2,TMEM37,NCEH1,STXBP1,FANK1,PDK1,OGDHL,SATB2,SHISA2,TTC22,ACVR2B,PRDM1,PALLD,B4GALNT3,GPR137C,RERE,TRIB3,FGR,ADAMTS3,ISM1,PLK2,WFS1,MAP2K6,WWTR1,HK2,CLMN,MAPK13,MYOM2,DDIT3 |
| 6.272e-03 | -5.07 | GO_CELL_CELL_JUNCTION_ASSEMBLY | MSigDB lists | GO_CELL_CELL_JUNCTION_ASSEMBLY | 72 | 5 | 17377 | 282 |
ARL2,WNT11,TLN2,PRKCA,MARVELD2 |
| 6.294e-03 | -5.07 | DH_2 | prosite domains | PS50010 | 70 | 5 | 12060 | 202 |
ARHGEF11,RASGRF2,TIAM2,SPATA13,PLEKHG1 |
| 6.312e-03 | -5.07 | human chr1q25.2 | chromosome location | human chr1q25.2 | 30 | 3 | 26185 | 331 |
QSOX1,RASAL2,RALGPS2 |
| 6.324e-03 | -5.06 | embryonic organ development | biological process | GO:0048568 | 418 | 14 | 17256 | 270 |
MSX1,ACVR1,RUNX2,ST14,DLX6,RBPMS2,MAFB,WNT11,CEBPA,SATB2,PRDM1,DLX2,OVOL2,COBL |
| 6.361e-03 | -5.06 | GO_ODONTOGENESIS | MSigDB lists | GO_ODONTOGENESIS | 102 | 6 | 17377 | 282 |
ENAM,SCN5A,MSX1,ACVR2B,DLX2,RUNX2 |
| 6.395e-03 | -5.05 | GO_TUBE_MORPHOGENESIS | MSigDB lists | GO_TUBE_MORPHOGENESIS | 321 | 12 | 17377 | 282 |
EPB41L5,ACVR1,LGR4,ST14,KLHL3,DACT1,MYC,WNT11,DAB2IP,ACVR2B,OVOL2,COBL |
| 6.406e-03 | -5.05 | FERM_CS | interpro domains | IPR019747 | 24 | 3 | 18492 | 296 |
EPB41L5,TLN2,PTPN21 |
| 6.418e-03 | -5.05 | activation of signaling protein activity involved in unfolded protein response | biological process | GO:0006987 | 8 | 2 | 17256 | 270 |
DAB2IP,ERN1 |
| 6.418e-03 | -5.05 | collateral sprouting | biological process | GO:0048668 | 8 | 2 | 17256 | 270 |
BDNF,COBL |
| 6.418e-03 | -5.05 | blood vessel maturation | biological process | GO:0001955 | 8 | 2 | 17256 | 270 |
RECK,DDIT3 |
| 6.456e-03 | -5.04 | CUT | smart domains | SM01109 | 7 | 2 | 9493 | 172 |
SATB2,SATB1 |
| 6.488e-03 | -5.04 | GO_POSITIVE_REGULATION_OF_ADENYLATE_CYCLASE_ACTIVITY | MSigDB lists | GO_POSITIVE_REGULATION_OF_ADENYLATE_CYCLASE_ACTIVITY | 46 | 4 | 17377 | 282 |
PRKCA,TSHR,WFS1,ADCY1 |
| 6.489e-03 | -5.04 | regulation of actin filament-based process | biological process | GO:0032970 | 376 | 13 | 17256 | 270 |
SCN5A,PHLDB2,PPM1E,PXN,DSTN,PRKCD,ARHGAP28,TMOD2,WNT11,PDE4D,PFN2,JAM3,FHOD3 |
| 6.495e-03 | -5.04 | regulation of actin filament organization | biological process | GO:0110053 | 252 | 10 | 17256 | 270 |
PHLDB2,PPM1E,PXN,DSTN,PRKCD,ARHGAP28,TMOD2,WNT11,PFN2,FHOD3 |
| 6.538e-03 | -5.03 | GO_ENZYME_ACTIVATOR_ACTIVITY | MSigDB lists | GO_ENZYME_ACTIVATOR_ACTIVITY | 447 | 15 | 17377 | 282 |
ARHGAP26,RGS17,RGS16,RASAL2,ARHGEF11,DOCK1,PRKCD,SRGAP1,ARHGAP28,WNT11,DAB2IP,GAS6,TBC1D16,TIAM2,TBC1D8 |
| 6.542e-03 | -5.03 | hindbrain development | biological process | GO:0030902 | 140 | 7 | 17256 | 270 |
NLGN4X,MAFB,SCN5A,ABAT,CBLN1,RERE,PLXNA2 |
| 6.546e-03 | -5.03 | regulation of supramolecular fiber organization | biological process | GO:1902903 | 334 | 12 | 17256 | 270 |
PHLDB2,PPM1E,PXN,DSTN,PRKCD,ARHGAP28,ARL2,CHADL,TMOD2,WNT11,PFN2,FHOD3 |
| 6.565e-03 | -5.03 | haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-follicular_lymphoma | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-follicular_lymphoma | 1003 | 27 | 17385 | 281 |
CCDC148,DOCK1,UBASH3B,CAPN5,ADCY1,SETBP1,NLGN4X,SATB2,RAB38,ITPR2,PRKCA,B4GALNT3,RADIL,HMCN1,FHOD3,MTUS1,ZNF827,ADAMTS3,GPR155,EBF4,GAN,GTF2F2,CLMN,DNAH5,COBL,TBC1D8,PGBD5 |
| 6.591e-03 | -5.02 | pleura | COSMIC cancer mutations | pleura | 4983 | 100 | 17385 | 281 |
ARHGAP26,ACVR1,DUSP8,LGR4,DOCK1,PTPN21,PLXNA2,ITPR2,COLEC10,PRKCA,KIF21B,CPNE2,FKBP9,PPM1E,PMAIP1,MARVELD2,DACT1,RPS6KL1,ZNF521,MAP7,PJA1,PDE4D,RAB27B,TLN2,DNAH5,HSPA2,GAPDH,PDK1,KLHL23,PTPN6,BNIP3L,NLGN4X,SATB2,WNT11,PLEKHA1,RAB38,ACVR2B,SGK2,SAV1,TBC1D16,PLEKHB1,DYRK1B,PLK2,RASGRF2,ERN1,ALDOA,TNFSF15,MAPK13,DISP1,TANC2,TMEM63C,RGS16,MXI1,RUNX2,ARHGEF11,FBXO4,BIK,SETBP1,ARL2,TNFRSF10C,GAS6,DYNC1I1,SATB1,FHOD3,RGS17,NUMBL,RALGPS2,MYC,PRKCD,RASD2,SRGAP1,TRIM3,SGK1,BNIP3,PXN,MPP1,NUAK2,SPATA13,PPFIA4,MAFB,STRADB,WWC1,PRDM1,PALLD,GPLD1,TRIB3,FGR,ADAMTS3,FMO4,GNAO1,MAP2K6,LRRIQ3,HK2,CLMN,TNFRSF17,IQSEC2,RNF157,RNF122,SMYD3,DDIT3 |
| 6.623e-03 | -5.02 | tissue development | biological process | GO:0009888 | 1660 | 39 | 17256 | 270 |
ZNF516,RUNX2,ACVR1,LGR4,ST14,BVES,PLXNA2,OVOL2,SATB1,MYORG,FHOD3,EPCAM,DACT1,DLX6,MYC,MARVELD2,ACTA2,MYH15,PDE4D,BARX1,B9D1,EPB41L5,ENAM,SLC40A1,MSX1,KLHL3,SOX21,SATB2,WNT11,PRDM1,ACVR2B,PALLD,SAV1,GPLD1,DYRK1B,WWTR1,MYOM2,DLX2,COBL |
| 6.627e-03 | -5.02 | Effects of PIP2 hydrolysis | REACTOME pathways | R-HSA-114508 | 27 | 3 | 10287 | 148 |
ITPR2,ABHD6,PRKCD |
| 6.646e-03 | -5.01 | GNF2_DNM1 | MSigDB lists | GNF2_DNM1 | 73 | 5 | 17377 | 282 |
KIF5C,NRN1,STXBP1,EHD3,PGBD5 |
| 6.650e-03 | -5.01 | GARGALOVIC_RESPONSE_TO_OXIDIZED_PHOSPHOLIPIDS_RED_DN | MSigDB lists | GARGALOVIC_RESPONSE_TO_OXIDIZED_PHOSPHOLIPIDS_RED_DN | 24 | 3 | 17377 | 282 |
MAFB,KLHL3,VGLL4 |
| 6.650e-03 | -5.01 | ZHENG_FOXP3_TARGETS_UP | MSigDB lists | ZHENG_FOXP3_TARGETS_UP | 24 | 3 | 17377 | 282 |
P4HA1,PRDM1,UBASH3B |
| 6.665e-03 | -5.01 | GO_NEGATIVE_REGULATION_OF_PROTEIN_COMPLEX_ASSEMBLY | MSigDB lists | GO_NEGATIVE_REGULATION_OF_PROTEIN_COMPLEX_ASSEMBLY | 103 | 6 | 17377 | 282 |
SGK1,TMOD2,PFN2,DACT1,PRKCD,FHOD3 |
| 6.683e-03 | -5.01 | BTB-kelch_protein | interpro domains | IPR017096 | 47 | 4 | 18492 | 296 |
KLHL31,KLHL3,KLHL23,GAN |
| 6.691e-03 | -5.01 | regulation of cellular component organization | biological process | GO:0051128 | 2369 | 52 | 17256 | 270 |
NECAB2,ARHGEF11,DOCK1,BVES,C4A,FBXO4,BIK,PLXNA2,ARL2,CHADL,SLX1B,GAS6,PFN2,CBLN1,FHOD3,NCS1,PPM1E,PMAIP1,DACT1,MYC,PRKCD,EHD3,GTF2F2,SGK1,DAB2IP,BNIP3,STXBP1,HSPA2,TBC1D8,EPB41L5,ENAM,BDNF,LZTS3,PHLDB2,PXN,MSX1,WISP3,DSTN,BNIP3L,WNT11,SGK2,TBC1D16,TLR6,JAM3,CENPV,FGR,PLK2,ALDOA,HK2,ARHGAP28,TMOD2,COBL |
| 6.754e-03 | -5.00 | NADH regeneration | biological process | GO:0006735 | 25 | 3 | 17256 | 270 |
GAPDH,ALDOA,HK2 |
| 6.754e-03 | -5.00 | glucose catabolic process to pyruvate | biological process | GO:0061718 | 25 | 3 | 17256 | 270 |
GAPDH,ALDOA,HK2 |
| 6.754e-03 | -5.00 | canonical glycolysis | biological process | GO:0061621 | 25 | 3 | 17256 | 270 |
GAPDH,ALDOA,HK2 |
| 6.767e-03 | -5.00 | cell development | biological process | GO:0048468 | 1556 | 37 | 17256 | 270 |
ACVR1,RUNX2,BVES,ST14,PLXNA2,KIF5C,CEBPA,OVOL2,PRKCA,RADIL,MYORG,FHOD3,NEO1,NUMBL,MARVELD2,ACTA2,SGK1,DAB2IP,PDE4D,STXBP1,HSPA2,EPB41L5,BDNF,PTPN6,ADCY1,EFNA3,SATB2,PRDM1,PALLD,JAM3,RERE,GNAO1,CLMN,MYOM2,TMOD2,SMYD3,COBL |
| 6.801e-03 | -4.99 | MAPK signaling pathway | KEGG pathways | ko04010 | 255 | 10 | 7161 | 113 |
BDNF,DUSP8,MAP2K6,MYC,RASGRF2,MAPK13,PRKCA,CACNB4,HSPA2,DDIT3 |
| 6.801e-03 | -4.99 | MAPK signaling pathway | KEGG pathways | hsa04010 | 255 | 10 | 7161 | 113 |
BDNF,DUSP8,MAP2K6,MYC,RASGRF2,MAPK13,PRKCA,CACNB4,HSPA2,DDIT3 |
| 6.801e-03 | -4.99 | GO_HINDBRAIN_DEVELOPMENT | MSigDB lists | GO_HINDBRAIN_DEVELOPMENT | 136 | 7 | 17377 | 282 |
NLGN4X,MAFB,SCN5A,ABAT,CBLN1,RERE,PLXNA2 |
| 6.834e-03 | -4.99 | Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate | KEGG pathways | M00001 | 25 | 3 | 7161 | 113 |
GAPDH,ALDOA,HK2 |
| 6.834e-03 | -4.99 | Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate | KEGG pathways | hsa_M00001 | 25 | 3 | 7161 | 113 |
GAPDH,ALDOA,HK2 |
| 6.851e-03 | -4.98 | ductal_carcinoma | COSMIC cancer mutations | ductal_carcinoma | 16293 | 273 | 17385 | 281 |
ARHGAP26,ACVR1,DUSP8,LGR4,RECK,LSM11,ALG1L,CEBPA,PRKCA,ABHD6,NCS1,EPDR1,PMAIP1,CFHR1,TMEM37,TSHR,TBC1D8,KLHL23,KLHL3,WISP3,EXOC6B,DSTN,BNIP3L,SLC25A28,ABCC2,TNS1,ACVR2B,SAV1,SPATA9,PLK2,RASGRF2,ALDOA,ARHGAP28,MAPK13,TMOD2,TANC2,SCN5A,TMEM63C,ZHX3,CYP2J2,SLC36A4,TNFRSF10C,DYNC1I1,HPCAL4,NIPSNAP3B,MTUS1,IL17D,RALGPS2,MYC,ZIC5,SRGAP1,MOXD1,STXBP1,GPR161,EPB41L5,BDNF,QSOX1,SHISA2,ARRDC4,OR11H4,ZNF558,ADAMTS3,ISM1,LRRIQ3,QPCTL,EMILIN2,CLMN,IQSEC2,SMYD3,ZNF516,RASAL2,ST14,FAM131C,C4A,CCDC110,PLXNA2,COLEC10,TIAM2,TMEM53,ZNF827,KMO,DACT1,DAB2IP,PJA1,PDE4D,RAB27B,DNAH5,ATP6AP1L,KIAA1549,C3orf67,GAPDH,PDK1,SOX21,CYB5R2,SFXN4,ADCY1,NLGN4X,SATB2,WNT11,RAB38,TBC1D16,IQCK,WFS1,WWTR1,PLEKHG1,P4HA1,TNFSF15,DBP,COBL,KCTD1,C2orf88,CCDC148,MXI1,TMEM132C,BACE1,BIK,CCNJL,KIF5C,ARL2,GAS6,ZNF219,NEO1,RGS17,GPR155,SMPDL3A,PARP9,TMC7,MN1,B9D1,SLC40A1,PXN,MPP1,GPR137C,GPLD1,TRIB3,FGR,GNAO1,MYOM2,TNFRSF17,DDIT3,B4GALT7,PHC1,CCDC126,ACSL1,HEBP1,PTPN21,NDRG2,NRN1,ABAT,ITPR2,SLC2A13,ABHD4,HMCN1,EPCAM,PPM1E,FKBP9,CPNE2,MARVELD2,DLX6,TMEM143,TLN2,FANK1,OR2W3,ZNF391,PGBD5,PNRC1,CAPN5,TTC22,PLEKHA1,SGK2,NT5DC2,PLEKHB1,DYRK1B,SPNS1,TCF7L1,ERN1,DLX2,APBA2,GPR63,LONRF1,RGS16,RUNX2,ZNF395,BVES,FBXO4,UBASH3B,CYP4V2,ATP6V1E2,RASL11B,SETBP1,CHADL,SATB1,PFN2,FHOD3,NUMBL,SLC30A4,GAN,EBF4,BNIP3,NCEH1,VGLL4,BARX1,IL17RD,SPATA13,EFNA3,MAFB,STRADB,WWC1,WDR25,PPFIA4,LHPP,PRDM1,B4GALNT3,KIAA0355,HK2,RNF122,DOCK1,RHPN2,FAM198B,KIF21B,RADIL,CBLN1,KCTD15,RPS6KL1,EEPD1,ZDHHC23,ZNF521,MAP7,MYH15,TMEM120B,HSPA2,FAM78B,PHLDB2,UROS,PTPN6,SLC39A8,JAM3,CENPV,IFT81,LMLN,ANKRD31,RBPMS2,DISP1,NECAB2,PRSS16,ARHGEF11,BLVRB,OVOL2,PRKCD,RASD2,EHD3,GTF2F2,ACTA2,PRICKLE2,TRIM3,SGK1,CCDC122,KIAA0408,MSX1,NUAK2,OGDHL,EXOG,PALLD,TLR6,CTIF,RERE,FMO4,MAP2K6,KIAA0513,ZNF474,THAP10,RNF157,PKIA |
| 6.862e-03 | -4.98 | large_cell_carcinoma | COSMIC cancer mutations | large_cell_carcinoma | 862 | 24 | 17385 | 281 |
PHLDB2,ACVR1,PDK1,EXOC6B,NUAK2,STRADB,CEBPA,ACVR2B,SGK2,PRKCA,RADIL,RERE,DYRK1B,TRIB3,FGR,PLK2,RPS6KL1,MAP2K6,PRKCD,ERN1,SGK1,MYOM2,MAPK13,OR2W3 |
| 6.862e-03 | -4.98 | lung-carcinoma-large_cell_carcinoma | COSMIC cancer mutations | lung-carcinoma-large_cell_carcinoma | 862 | 24 | 17385 | 281 |
PHLDB2,ACVR1,PDK1,EXOC6B,NUAK2,STRADB,CEBPA,ACVR2B,SGK2,PRKCA,RADIL,RERE,DYRK1B,TRIB3,FGR,PLK2,RPS6KL1,MAP2K6,PRKCD,ERN1,SGK1,MYOM2,MAPK13,OR2W3 |
| 6.874e-03 | -4.98 | V$MYB_Q5_01 | MSigDB lists | V$MYB_Q5_01 | 245 | 10 | 17377 | 282 |
BDNF,ADAMTS3,DOCK1,DACT1,HEBP1,ALDOA,OGDHL,DLX2,COLEC10,DDIT3 |
| 6.876e-03 | -4.98 | CHANDRAN_METASTASIS_DN | MSigDB lists | CHANDRAN_METASTASIS_DN | 284 | 11 | 17377 | 282 |
MN1,EPB41L5,SLC30A4,PRICKLE2,TNS1,LHPP,EPHB6,MOXD1,RAB27B,JAM3,FHOD3 |
| 6.889e-03 | -4.98 | BOYLAN_MULTIPLE_MYELOMA_PCA1_DN | MSigDB lists | BOYLAN_MULTIPLE_MYELOMA_PCA1_DN | 8 | 2 | 17377 | 282 |
PLK2,BLVRB |
| 6.889e-03 | -4.98 | MIKKELSEN_DEDIFFERENTIATED_STATE_UP | MSigDB lists | MIKKELSEN_DEDIFFERENTIATED_STATE_UP | 8 | 2 | 17377 | 282 |
COBL,PHC1 |
| 6.889e-03 | -4.98 | RAMJAUN_APOPTOSIS_BY_TGFB1_VIA_MAPK1_DN | MSigDB lists | RAMJAUN_APOPTOSIS_BY_TGFB1_VIA_MAPK1_DN | 8 | 2 | 17377 | 282 |
TRIB3,DDIT3 |
| 6.894e-03 | -4.98 | GSE6259_BCELL_VS_CD8_TCELL_DN | MSigDB lists | GSE6259_BCELL_VS_CD8_TCELL_DN | 171 | 8 | 17377 | 282 |
LONRF1,C2orf88,ACVR2B,RAB27B,KIF21B,SATB1,ADAMTS3,RERE |
| 6.959e-03 | -4.97 | regulation of kinase activity | biological process | GO:0043549 | 892 | 24 | 17256 | 270 |
ACSL1,DUSP8,PTPN6,UBASH3B,ADCY1,STRADB,CEBPA,WNT11,GAS6,ACVR2B,TLR6,TRIB3,PPM1E,FGR,MAP2K6,PRKCD,WWTR1,ERN1,INAVA,TNFSF15,DAB2IP,EPHB6,SMYD3,PKIA |
| 7.017e-03 | -4.96 | CHYLA_CBFA2T3_TARGETS_UP | MSigDB lists | CHYLA_CBFA2T3_TARGETS_UP | 366 | 13 | 17377 | 282 |
TMEM53,PRSS16,RALGPS2,UBASH3B,CYP2J2,BACE1,DSTN,EHD3,ERN1,EEPD1,PLEKHA1,RAB27B,MTUS1 |
| 7.031e-03 | -4.96 | nucleoside phosphate catabolic process | biological process | GO:1901292 | 108 | 6 | 17256 | 270 |
PDE4D,GAPDH,SMPDL3A,ALDOA,OGDHL,HK2 |
| 7.070e-03 | -4.95 | GSE6259_FLT3L_INDUCED_33D1_POS_DC_VS_CD8_TCELL_DN | MSigDB lists | GSE6259_FLT3L_INDUCED_33D1_POS_DC_VS_CD8_TCELL_DN | 137 | 7 | 17377 | 282 |
RUNX2,CFHR1,HEBP1,ALDOA,ATOX1,GTF2F2,TBC1D8 |
| 7.099e-03 | -4.95 | GALNT6 (polypeptide N-acetylgalactosaminyltransferase 6) | protein interactions | 11226 | 24 | 3 | 17029 | 283 |
GAS6,ALDOA,PLXNA2 |
| 7.113e-03 | -4.95 | CGN (cingulin) | protein interactions | 57530 | 102 | 6 | 17029 | 283 |
ACTA2,PHLDB2,DAB2IP,RALGPS2,RASAL2,TANC2 |
| 7.118e-03 | -4.95 | apoptotic signaling pathway | biological process | GO:0097190 | 296 | 11 | 17256 | 270 |
TRIB3,PDK1,PMAIP1,PRKCD,ERN1,BNIP3L,BNIP3,DAB2IP,TNFRSF10C,PRKCA,DDIT3 |
| 7.131e-03 | -4.94 | GSE4984_LPS_VS_VEHICLE_CTRL_TREATED_DC_UP | MSigDB lists | GSE4984_LPS_VS_VEHICLE_CTRL_TREATED_DC_UP | 172 | 8 | 17377 | 282 |
ATP6V1E2,ZNF474,LMLN,RNF157,KLHL3,MPP1,CYP2J2,PTPN6 |
| 7.131e-03 | -4.94 | GSE46242_CTRL_VS_EGR2_DELETED_TH1_CD4_TCELL_DN | MSigDB lists | GSE46242_CTRL_VS_EGR2_DELETED_TH1_CD4_TCELL_DN | 172 | 8 | 17377 | 282 |
TMEM53,PHLDB2,ACSL1,BLVRB,DISP1,ABHD6,PGBD5,PARP9 |
| 7.131e-03 | -4.94 | GSE37416_CTRL_VS_12H_F_TULARENSIS_LVS_NEUTROPHIL_DN | MSigDB lists | GSE37416_CTRL_VS_12H_F_TULARENSIS_LVS_NEUTROPHIL_DN | 172 | 8 | 17377 | 282 |
MXI1,PDK1,ZNF395,VGLL4,ALDOA,DDIT3,HK2,BNIP3L |
| 7.156e-03 | -4.94 | Regulation of RAC1 activity | Pathway Interaction DB | rac1_reg_pathway | 39 | 4 | 2226 | 45 |
DOCK1,RASGRF2,TIAM2,SPATA13 |
| 7.168e-03 | -4.94 | IVANOVA_HEMATOPOIESIS_STEM_CELL_AND_PROGENITOR | MSigDB lists | IVANOVA_HEMATOPOIESIS_STEM_CELL_AND_PROGENITOR | 629 | 19 | 17377 | 282 |
MN1,QSOX1,RUNX2,UBASH3B,CYP4V2,WNT11,TTC22,LHPP,RAB38,TBC1D16,NCS1,ZNF827,ZNF521,PRICKLE2,DISP1,STXBP1,KIAA1549,KCTD1,PHC1 |
| 7.168e-03 | -4.94 | regulation of small GTPase mediated signal transduction | biological process | GO:0051056 | 338 | 12 | 17256 | 270 |
ARHGAP26,RALGPS2,RASAL2,ARHGEF11,RASGRF2,PLEKHG1,SRGAP1,SPATA13,ARHGAP28,DAB2IP,IQSEC2,TIAM2 |
| 7.213e-03 | -4.93 | DCDC1 (doublecortin domain containing 1) | protein interactions | 341019 | 8 | 2 | 17029 | 283 |
DYNC1I1,GAN |
| 7.222e-03 | -4.93 | breast-carcinoma-lobular_carcinoma | COSMIC cancer mutations | breast-carcinoma-lobular_carcinoma | 771 | 22 | 17385 | 281 |
MXI1,ACVR1,PDK1,ARHGEF11,NUAK2,STRADB,CEBPA,ACVR2B,SGK2,PRKCA,RERE,DYRK1B,TRIB3,FGR,PLK2,MYC,RPS6KL1,MAP2K6,PRKCD,ERN1,SGK1,MAPK13 |
| 7.222e-03 | -4.93 | lobular_carcinoma | COSMIC cancer mutations | lobular_carcinoma | 771 | 22 | 17385 | 281 |
MXI1,ACVR1,PDK1,ARHGEF11,NUAK2,STRADB,CEBPA,ACVR2B,SGK2,PRKCA,RERE,DYRK1B,TRIB3,FGR,PLK2,MYC,RPS6KL1,MAP2K6,PRKCD,ERN1,SGK1,MAPK13 |
| 7.261e-03 | -4.93 | V$PAX4_01 | MSigDB lists | V$PAX4_01 | 247 | 10 | 17377 | 282 |
ZNF827,BDNF,MXI1,CAPN5,TRIM3,SLC25A28,PRDM1,PDE4D,PLEKHA1,DDIT3 |
| 7.261e-03 | -4.93 | V$AP1_Q4_01 | MSigDB lists | V$AP1_Q4_01 | 247 | 10 | 17377 | 282 |
ZNF827,GAPDH,SCAMP1,ALDOA,NDRG2,BNIP3,PRDM1,ABHD4,COBL,DDIT3 |
| 7.261e-03 | -4.93 | V$OCT1_Q6 | MSigDB lists | V$OCT1_Q6 | 247 | 10 | 17377 | 282 |
BDNF,TCF7L1,MAP2K6,PLXNA2,TMOD2,SATB2,PRDM1,PDE4D,JAM3,MTUS1 |
| 7.276e-03 | -4.92 | positive regulation of macromolecule metabolic process | biological process | GO:0010604 | 3113 | 65 | 17256 | 270 |
ACSL1,ZNF516,ACVR1,LGR4,CEBPA,PRKCA,EPCAM,PMAIP1,DACT1,DAB2IP,EPHB6,FANK1,HSPA2,SOX21,ADCY1,WNT11,SATB2,PXYLP1,ACVR2B,DYRK1B,PLK2,WFS1,ERN1,WWTR1,TNFSF15,DLX2,DBP,LONRF1,NECAB2,RUNX2,BVES,ARHGEF11,FBXO4,SLX1B,OVOL2,TNFRSF10C,GAS6,ZNF219,PFN2,KDM7A,MYC,RASD2,PRKCD,EBF4,GTF2F2,INAVA,ACTA2,BARX1,PARP9,SLC40A1,MSX1,EFNA3,MAFB,STRADB,WWC1,GAREM1,PRDM1,ARRDC4,TLR6,GPLD1,RERE,TRIB3,MAP2K6,SMYD3,DDIT3 |
| 7.288e-03 | -4.92 | regulation of transferase activity | biological process | GO:0051338 | 995 | 26 | 17256 | 270 |
ACSL1,DUSP8,PTPN6,UBASH3B,ADCY1,STRADB,CEBPA,WNT11,GAS6,ACVR2B,ARRDC4,TLR6,TRIB3,PPM1E,FGR,MAP2K6,MYC,PRKCD,WWTR1,ERN1,INAVA,TNFSF15,DAB2IP,EPHB6,SMYD3,PKIA |
| 7.321e-03 | -4.92 | platelet activation | biological process | GO:0030168 | 143 | 7 | 17256 | 270 |
ITPR2,GAS6,PRKCA,STXBP1,UBASH3B,PTPN6,PRKCD |
| 7.345e-03 | -4.91 | CaM pathway | REACTOME pathways | R-HSA-111997 | 28 | 3 | 10287 | 148 |
PRKCA,PRKCD,ADCY1 |
| 7.345e-03 | -4.91 | Calmodulin induced events | REACTOME pathways | R-HSA-111933 | 28 | 3 | 10287 | 148 |
PRKCA,PRKCD,ADCY1 |
| 7.346e-03 | -4.91 | nicotinamide nucleotide metabolic process | biological process | GO:0046496 | 109 | 6 | 17256 | 270 |
GAPDH,KMO,ALDOA,PARP9,OGDHL,HK2 |
| 7.346e-03 | -4.91 | pyridine nucleotide metabolic process | biological process | GO:0019362 | 109 | 6 | 17256 | 270 |
GAPDH,KMO,ALDOA,PARP9,OGDHL,HK2 |
| 7.348e-03 | -4.91 | WEI_MIR34A_TARGETS | MSigDB lists | WEI_MIR34A_TARGETS | 138 | 7 | 17377 | 282 |
NUMBL,ZNF395,RALGPS2,LGR4,PALLD,RECK,PKIA |
| 7.380e-03 | -4.91 | mouth | COSMIC cancer mutations | mouth | 9240 | 170 | 17385 | 281 |
ARHGAP26,ACSL1,ACVR1,DUSP8,LGR4,RECK,HEBP1,PTPN21,NDRG2,CEBPA,SLC2A13,ITPR2,ABAT,PRKCA,HMCN1,NCS1,EPDR1,EPCAM,CPNE2,FKBP9,PPM1E,CFHR1,TMEM143,TMEM37,TLN2,OR2W3,TSHR,FANK1,TBC1D8,PGBD5,KLHL3,TTC22,ABCC2,TNS1,ACVR2B,SGK2,DYRK1B,TCF7L1,PLK2,RASGRF2,ERN1,MAPK13,TMOD2,TANC2,LONRF1,GPR63,TMEM63C,SCN5A,RUNX2,ZNF395,ZHX3,CYP2J2,FBXO4,SETBP1,RASL11B,ATP6V1E2,CHADL,SLC36A4,TNFRSF10C,PFN2,SATB1,FHOD3,MTUS1,NUMBL,RALGPS2,ZIC5,EBF4,SRGAP1,BNIP3,VGLL4,EPB41L5,IL17RD,QSOX1,SPATA13,PPFIA4,WWC1,PRDM1,ARRDC4,B4GALNT3,ZNF558,KIAA0355,LRRIQ3,EMILIN2,HK2,CLMN,IQSEC2,RNF122,SMYD3,ZNF516,DOCK1,ST14,FAM131C,CCDC110,PLXNA2,FAM198B,KIF21B,RADIL,TIAM2,ZNF827,KCTD15,RPS6KL1,DACT1,EEPD1,ZDHHC23,ZNF521,MAP7,MYH15,RAB27B,DNAH5,TMEM120B,FAM78B,ATP6AP1L,HSPA2,KIAA1549,C3orf67,PHLDB2,GAPDH,PDK1,SLC39A8,SOX21,PTPN6,ADCY1,NLGN4X,SATB2,RAB38,TBC1D16,LMLN,ANKRD31,WFS1,PLEKHG1,DBP,KLHL31,COBL,KCTD1,CCDC148,TMEM132C,PRSS16,ARHGEF11,CCNJL,KIF5C,ARL2,OVOL2,ZNF219,NEO1,RGS17,PRKCD,RASD2,GTF2F2,PRICKLE2,SGK1,PARP9,MN1,SLC40A1,PXN,NUAK2,OGDHL,PALLD,GPR137C,TLR6,RERE,CTIF,TRIB3,FGR,MAP2K6,MYOM2,ZNF474,THAP10,DDIT3,B4GALT7,PHC1 |
| 7.420e-03 | -4.90 | GO_ANATOMICAL_STRUCTURE_FORMATION_INVOLVED_IN_MORPHOGENESIS | MSigDB lists | GO_ANATOMICAL_STRUCTURE_FORMATION_INVOLVED_IN_MORPHOGENESIS | 912 | 25 | 17377 | 282 |
B9D1,EPB41L5,ENAM,SLC40A1,MSX1,ACVR1,ST14,PTPN6,PLXNA2,WNT11,ACVR2B,OVOL2,PRKCA,JAM3,CBLN1,FHOD3,GPLD1,DYRK1B,IFT81,DLX6,EHD3,TMOD2,DAB2IP,DNAH5,COBL |
| 7.468e-03 | -4.90 | GO_REGULATION_OF_ENDOPLASMIC_RETICULUM_UNFOLDED_PROTEIN_RESPONSE | MSigDB lists | GO_REGULATION_OF_ENDOPLASMIC_RETICULUM_UNFOLDED_PROTEIN_RESPONSE | 25 | 3 | 17377 | 282 |
DAB2IP,WFS1,ERN1 |
| 7.468e-03 | -4.90 | KIM_HYPOXIA | MSigDB lists | KIM_HYPOXIA | 25 | 3 | 17377 | 282 |
BNIP3,ALDOA,BNIP3L |
| 7.468e-03 | -4.90 | GO_REGULATION_OF_ACTIVIN_RECEPTOR_SIGNALING_PATHWAY | MSigDB lists | GO_REGULATION_OF_ACTIVIN_RECEPTOR_SIGNALING_PATHWAY | 25 | 3 | 17377 | 282 |
ACVR2B,ACVR1,DACT1 |
| 7.469e-03 | -4.90 | REACTOME_SIGNALLING_BY_NGF | MSigDB lists | REACTOME_SIGNALLING_BY_NGF | 210 | 9 | 17377 | 282 |
TRIB3,ARHGEF11,RASGRF2,PRKCD,ADCY1,MAPK13,ITPR2,PRKCA,TIAM2 |
| 7.474e-03 | -4.90 | GO_PATTERN_SPECIFICATION_PROCESS | MSigDB lists | GO_PATTERN_SPECIFICATION_PROCESS | 411 | 14 | 17377 | 282 |
EPB41L5,MSX1,ACVR1,PLXNA2,MAFB,SATB2,ACVR2B,DLX2,DISP1,OVOL2,DNAH5,BARX1,COBL,DDIT3 |
| 7.544e-03 | -4.89 | GO_LATERAL_PLASMA_MEMBRANE | MSigDB lists | GO_LATERAL_PLASMA_MEMBRANE | 48 | 4 | 17377 | 282 |
EPCAM,ARL2,SCN5A,BVES |
| 7.544e-03 | -4.89 | MODULE_201 | MSigDB lists | MODULE_201 | 48 | 4 | 17377 | 282 |
SCN5A,MYOM2,GNAO1,ALDOA |
| 7.548e-03 | -4.89 | positive regulation of membrane permeability | biological process | GO:1905710 | 26 | 3 | 17256 | 270 |
BNIP3,PMAIP1,BNIP3L |
| 7.548e-03 | -4.89 | glycolytic process through glucose-6-phosphate | biological process | GO:0061620 | 26 | 3 | 17256 | 270 |
GAPDH,ALDOA,HK2 |
| 7.548e-03 | -4.89 | glycolytic process through fructose-6-phosphate | biological process | GO:0061615 | 26 | 3 | 17256 | 270 |
GAPDH,ALDOA,HK2 |
| 7.548e-03 | -4.89 | regulation of odontogenesis | biological process | GO:0042481 | 26 | 3 | 17256 | 270 |
ENAM,RUNX2,MSX1 |
| 7.561e-03 | -4.88 | GO_KINASE_BINDING | MSigDB lists | GO_KINASE_BINDING | 587 | 18 | 17377 | 282 |
SCN5A,PXN,PTPN6,WWC1,CEBPA,GAS6,CACNB4,NCS1,TRIB3,FGR,MAP2K6,DACT1,PRKCD,SGK1,ACTA2,DAB2IP,STXBP1,PKIA |
| 7.625e-03 | -4.88 | GSE22611_MUTANT_NOD2_VS_CTRL_TRANSDUCED_HEK293T_CELL_DN | MSigDB lists | GSE22611_MUTANT_NOD2_VS_CTRL_TRANSDUCED_HEK293T_CELL_DN | 174 | 8 | 17377 | 282 |
PPM1E,SLC30A4,ZHX3,RECK,GNAO1,CLMN,TMEM120B,TBC1D16 |
| 7.625e-03 | -4.88 | GSE25088_WT_VS_STAT6_KO_MACROPHAGE_ROSIGLITAZONE_STIM_UP | MSigDB lists | GSE25088_WT_VS_STAT6_KO_MACROPHAGE_ROSIGLITAZONE_STIM_UP | 174 | 8 | 17377 | 282 |
P4HA1,TRIB3,PJA1,ARRDC4,VGLL4,IGIP,GPR155,ALDOA |
| 7.635e-03 | -4.88 | negative regulation of phosphorylation | biological process | GO:0042326 | 472 | 15 | 17256 | 270 |
TRIB3,PPM1E,DUSP8,DACT1,PTPN6,MYC,UBASH3B,PRKCD,WWTR1,NDRG2,DAB2IP,CEBPA,PDE4D,SMYD3,PKIA |
| 7.656e-03 | -4.87 | RhoGEF | smart domains | SM00325 | 68 | 5 | 9493 | 172 |
ARHGEF11,RASGRF2,TIAM2,SPATA13,PLEKHG1 |
| 7.664e-03 | -4.87 | GO_TUBE_DEVELOPMENT | MSigDB lists | GO_TUBE_DEVELOPMENT | 543 | 17 | 17377 | 282 |
EPB41L5,ACVR1,LGR4,ST14,KLHL3,PLXNA2,CEBPA,WNT11,PRDM1,ACVR2B,OVOL2,SAV1,EPCAM,MYC,DACT1,DAB2IP,COBL |
| 7.664e-03 | -4.87 | GO_EMBRYO_DEVELOPMENT_ENDING_IN_BIRTH_OR_EGG_HATCHING | MSigDB lists | GO_EMBRYO_DEVELOPMENT_ENDING_IN_BIRTH_OR_EGG_HATCHING | 543 | 17 | 17377 | 282 |
B9D1,EPB41L5,MSX1,ACVR1,RUNX2,ST14,PLXNA2,SATB2,WNT11,CEBPA,PRDM1,OVOL2,DACT1,DLX2,TANC2,APBA2,COBL |
| 7.664e-03 | -4.87 | Calcium Regulation in the Cardiac Cell | WikiPathways | WP536 | 151 | 8 | 5312 | 101 |
RGS16,RGS17,GNAO1,PRKCD,ADCY1,ITPR2,PRKCA,PKIA |
| 7.666e-03 | -4.87 | V$TTF1_Q6 | MSigDB lists | V$TTF1_Q6 | 249 | 10 | 17377 | 282 |
MXI1,MYC,ERN1,ZNF521,NDRG2,MAFB,CLMN,DAB2IP,OVOL2,HPCAL4 |
| 7.671e-03 | -4.87 | cellular response to antibiotic | biological process | GO:0071236 | 110 | 6 | 17256 | 270 |
MAPK13,BNIP3,ITPR2,PLEKHA1,PRKCD,ADCY1 |
| 7.752e-03 | -4.86 | oesophagus-carcinoma-squamous_cell_carcinoma | COSMIC cancer mutations | oesophagus-carcinoma-squamous_cell_carcinoma | 6668 | 128 | 17385 | 281 |
ACVR1,LGR4,RASAL2,DOCK1,ST14,RECK,CCDC110,PTPN21,RHPN2,NDRG2,ITPR2,FAM198B,ABAT,COLEC10,PRKCA,KIF21B,HMCN1,TIAM2,FKBP9,ZNF827,PPM1E,KCTD15,DLX6,MARVELD2,RPS6KL1,ZNF521,EEPD1,ZDHHC23,DAB2IP,MYH15,PDE4D,RAB27B,TLN2,DNAH5,TMEM120B,OR2W3,TSHR,HSPA2,TBC1D8,PGBD5,ZNF391,DZANK1,PHLDB2,WISP3,SFXN4,EXOC6B,DSTN,CAPN5,ADCY1,NLGN4X,SLC25A28,ABCC2,TNS1,ACVR2B,TBC1D16,PLEKHB1,SPNS1,DYRK1B,IFT81,LMLN,ANKRD31,PLK2,RASGRF2,ERN1,WWTR1,ALDOA,P4HA1,ARHGAP28,DISP1,TANC2,APBA2,COBL,GPR63,TMEM63C,SCN5A,CCDC148,TMEM132C,ZNF395,ZHX3,ARHGEF11,CYP2J2,CYP4V2,SETBP1,KIF5C,SLC36A4,ZNF219,SATB1,NIPSNAP3B,NEO1,MTUS1,ZIC5,PRKCD,EHD3,EBF4,SRGAP1,ACTA2,TRIM3,KIAA0408,NCEH1,VGLL4,STXBP1,GPR161,B9D1,IL17RD,MSX1,EFNA3,NUAK2,WDR25,WWC1,MAFB,PRDM1,PALLD,B4GALNT3,GPLD1,CTIF,FGR,ADAMTS3,FMO4,LRRIQ3,EMILIN2,CLMN,ZNF474,MYOM2,TNFRSF17,PKIA,DDIT3,B4GALT7,PHC1 |
| 7.799e-03 | -4.85 | LATS1 (large tumor suppressor kinase 1) | protein interactions | 9113 | 104 | 6 | 17029 | 283 |
WWC1,SAV1,KIAA1549,MYC,WWTR1,NUAK2 |
| 7.862e-03 | -4.85 | MORF_MYC | MSigDB lists | MORF_MYC | 76 | 5 | 17377 | 282 |
MSX1,ITPR2,PRSS16,MYC,PLEKHB1 |
| 7.874e-03 | -4.84 | embryo development ending in birth or egg hatching | biological process | GO:0009792 | 565 | 17 | 17256 | 270 |
EPB41L5,B9D1,MSX1,RUNX2,ACVR1,ST14,PLXNA2,SATB2,CEBPA,WNT11,PRDM1,OVOL2,DACT1,DLX2,TANC2,APBA2,COBL |
| 7.927e-03 | -4.84 | GCCNNNWTAAR_UNKNOWN | MSigDB lists | GCCNNNWTAAR_UNKNOWN | 140 | 7 | 17377 | 282 |
MN1,EPB41L5,NDRG2,CCDC126,MSX1,KCTD15,RALGPS2 |
| 7.927e-03 | -4.84 | PODAR_RESPONSE_TO_ADAPHOSTIN_UP | MSigDB lists | PODAR_RESPONSE_TO_ADAPHOSTIN_UP | 140 | 7 | 17377 | 282 |
TRIB3,MSX1,MXI1,PNRC1,PALLD,PMAIP1,DDIT3 |
| 7.927e-03 | -4.84 | GSE41867_LCMV_ARMSTRONG_VS_CLONE13_DAY15_EFFECTOR_CD8_TCELL_DN | MSigDB lists | GSE41867_LCMV_ARMSTRONG_VS_CLONE13_DAY15_EFFECTOR_CD8_TCELL_DN | 140 | 7 | 17377 | 282 |
PLEKHA1,DBP,ADAMTS3,ATP6AP1L,KIAA1549,RASD2,EEPD1 |
| 7.949e-03 | -4.83 | regulation of response to endoplasmic reticulum stress | biological process | GO:1905897 | 79 | 5 | 17256 | 270 |
DAB2IP,PMAIP1,WFS1,DDIT3,ERN1 |
| 7.949e-03 | -4.83 | positive regulation of response to DNA damage stimulus | biological process | GO:2001022 | 79 | 5 | 17256 | 270 |
MSX1,PMAIP1,MYC,PRKCD,PARP9 |
| 7.969e-03 | -4.83 | PLCB1 (phospholipase C beta 1) | protein interactions | 23236 | 25 | 3 | 17029 | 283 |
PRKCA,PRKCD,GAN |
| 7.977e-03 | -4.83 | - | gene3d domains | 1.20.900.10 | 70 | 5 | 8148 | 145 |
ARHGEF11,RASGRF2,TIAM2,SPATA13,PLEKHG1 |
| 7.987e-03 | -4.83 | REACTOME_SIGNALING_BY_FGFR | MSigDB lists | REACTOME_SIGNALING_BY_FGFR | 107 | 6 | 17377 | 282 |
IL17RD,TRIB3,ITPR2,PRKCA,PRKCD,ADCY1 |
| 8.003e-03 | -4.83 | GO_CYTOSKELETON_ORGANIZATION | MSigDB lists | GO_CYTOSKELETON_ORGANIZATION | 775 | 22 | 17377 | 282 |
ARHGAP26,EPB41L5,PHLDB2,GAPDH,ARHGEF11,DOCK1,DSTN,NUAK2,ARL2,PALLD,PFN2,FHOD3,PLK2,ALDOA,GAN,MAP7,SGK1,TMOD2,TLN2,IQSEC2,DNAH5,COBL |
| 8.056e-03 | -4.82 | regulation of transport | biological process | GO:0051049 | 1788 | 41 | 17256 | 270 |
SCN5A,NECAB2,LGR4,BVES,C4A,UBASH3B,ARL2,ITPR2,GAS6,ABAT,PRKCA,CACNB4,PFN2,NCS1,PMAIP1,KMO,PRKCD,EHD3,SGK1,PDE4D,TMEM37,RAB27B,STXBP1,HSPA2,TBC1D8,GAPDH,PTPN6,BNIP3L,WWC1,SGK2,TBC1D16,TLR6,GPLD1,TRIB3,FGR,MAP2K6,GNAO1,WFS1,HK2,DISP1,PKIA |
| 8.089e-03 | -4.82 | negative regulation of transcription by RNA polymerase II | biological process | GO:0000122 | 805 | 22 | 17256 | 270 |
MSX1,MXI1,ZHX3,WWC1,CEBPA,SATB2,PRDM1,ACVR2B,ZNF219,SATB1,RERE,TRIB3,DACT1,WFS1,MYC,WWTR1,DAB2IP,DLX2,KCTD1,PKIA,DDIT3,PARP9 |
| 8.112e-03 | -4.81 | SMIRNOV_RESPONSE_TO_IR_2HR_UP | MSigDB lists | SMIRNOV_RESPONSE_TO_IR_2HR_UP | 49 | 4 | 17377 | 282 |
SGK1,RGS16,PMAIP1,PLK2 |
| 8.112e-03 | -4.81 | MODULE_387 | MSigDB lists | MODULE_387 | 49 | 4 | 17377 | 282 |
ACTA2,MYOM2,SCN5A,ALDOA |
| 8.144e-03 | -4.81 | GSE24634_NAIVE_CD4_TCELL_VS_DAY3_IL4_CONV_TREG_UP | MSigDB lists | GSE24634_NAIVE_CD4_TCELL_VS_DAY3_IL4_CONV_TREG_UP | 176 | 8 | 17377 | 282 |
FKBP9,IQCK,KLHL3,KIAA0355,PLEKHA1,ACVR2B,TMEM120B,PLEKHB1 |
| 8.144e-03 | -4.81 | GSE2585_AIRE_KO_VS_WT_CD80_LOW_MTEC_UP | MSigDB lists | GSE2585_AIRE_KO_VS_WT_CD80_LOW_MTEC_UP | 176 | 8 | 17377 | 282 |
EPCAM,FKBP9,MSX1,TANC2,SAV1,SCAMP1,FMO4,CBLN1 |
| 8.144e-03 | -4.81 | GO_CELL_JUNCTION_ORGANIZATION | MSigDB lists | GO_CELL_JUNCTION_ORGANIZATION | 176 | 8 | 17377 | 282 |
NUMBL,MARVELD2,ARL2,NLGN4X,WNT11,TNS1,PRKCA,TLN2 |
| 8.144e-03 | -4.81 | GSE30971_CTRL_VS_LPS_STIM_MACROPHAGE_WBP7_KO_4H_DN | MSigDB lists | GSE30971_CTRL_VS_LPS_STIM_MACROPHAGE_WBP7_KO_4H_DN | 176 | 8 | 17377 | 282 |
KIAA0513,PRDM1,GAPDH,DISP1,NCEH1,RASAL2,STXBP1,UBASH3B |
| 8.154e-03 | -4.81 | protein serine/threonine kinase activity | molecular function | GO:0004674 | 505 | 16 | 17224 | 278 |
ACVR1,NUAK2,STRADB,ACVR2B,SGK2,PRKCA,GRK3,DYRK1B,PLK2,RPS6KL1,MAP2K6,ERN1,PRKCD,SGK1,MAPK13,EPHB6 |
| 8.161e-03 | -4.81 | AACTGGA,MIR-145 | MSigDB lists | AACTGGA,MIR-145 | 213 | 9 | 17377 | 282 |
EPB41L5,ARHGAP26,PHLDB2,PXN,HERC6,KIAA0355,DLX6,EFNA3,SRGAP1 |
| 8.167e-03 | -4.81 | negative regulation of excitatory postsynaptic potential | biological process | GO:0090394 | 9 | 2 | 17256 | 270 |
NLGN4X,CBLN1 |
| 8.167e-03 | -4.81 | embryonic foregut morphogenesis | biological process | GO:0048617 | 9 | 2 | 17256 | 270 |
EPB41L5,ACVR2B |
| 8.169e-03 | -4.81 | PR interval(PMID:20062060) | GWAS genes | PR interval(PMID:20062060) | 6 | 2 | 2388 | 58 |
WNT11,SCN5A |
| 8.232e-03 | -4.80 | regulation of organic acid transport | biological process | GO:0032890 | 51 | 4 | 17256 | 270 |
ABAT,KMO,STXBP1,MAP2K6 |
| 8.234e-03 | -4.80 | GO_CYTOSKELETAL_PROTEIN_BINDING | MSigDB lists | GO_CYTOSKELETAL_PROTEIN_BINDING | 777 | 22 | 17377 | 282 |
EPB41L5,SCN5A,GAPDH,PXN,KLHL3,DSTN,KIF5C,TNS1,KIF21B,PALLD,DYNC1I1,PFN2,FHOD3,IFT81,ALDOA,SGK1,CLMN,MYH15,TMOD2,TLN2,RAB27B,COBL |
| 8.249e-03 | -4.80 | human chr3p22.2 | chromosome location | human chr3p22.2 | 33 | 3 | 26185 | 331 |
SCN5A,ACVR2B,EXOG |
| 8.278e-03 | -4.79 | phosphorylation | biological process | GO:0016310 | 1261 | 31 | 17256 | 270 |
IL17RD,GAPDH,ACVR1,PDK1,RASAL2,PTPN6,OGDHL,NUAK2,STRADB,WNT11,GAS6,ACVR2B,SGK2,PRKCA,GRK3,DYRK1B,TRIB3,FGR,RASGRF2,PLK2,RPS6KL1,MYC,MAP2K6,PRKCD,ERN1,ALDOA,HK2,SGK1,DAB2IP,MAPK13,EPHB6 |
| 8.342e-03 | -4.79 | GO_REGULATION_OF_ENDOPLASMIC_RETICULUM_STRESS_INDUCED_INTRINSIC_APOPTOTIC_SIGNALING_PATHWAY | MSigDB lists | GO_REGULATION_OF_ENDOPLASMIC_RETICULUM_STRESS_INDUCED_INTRINSIC_APOPTOTIC_SIGNALING_PATHWAY | 26 | 3 | 17377 | 282 |
PMAIP1,WFS1,DDIT3 |
| 8.342e-03 | -4.79 | WANG_ADIPOGENIC_GENES_REPRESSED_BY_SIRT1 | MSigDB lists | WANG_ADIPOGENIC_GENES_REPRESSED_BY_SIRT1 | 26 | 3 | 17377 | 282 |
TRIB3,GAPDH,ALDOA |
| 8.344e-03 | -4.79 | FIGUEROA_AML_METHYLATION_CLUSTER_1_UP | MSigDB lists | FIGUEROA_AML_METHYLATION_CLUSTER_1_UP | 108 | 6 | 17377 | 282 |
MAP7,TBC1D16,PMAIP1,PFN2,CENPV,GAN |
| 8.351e-03 | -4.79 | odontogenesis | biological process | GO:0042476 | 112 | 6 | 17256 | 270 |
ENAM,SCN5A,MSX1,ACVR2B,DLX2,RUNX2 |
| 8.395e-03 | -4.78 | regulation of mitochondrial membrane permeability involved in apoptotic process | biological process | GO:1902108 | 27 | 3 | 17256 | 270 |
BNIP3,PMAIP1,BNIP3L |
| 8.395e-03 | -4.78 | negative regulation of protein localization to nucleus | biological process | GO:1900181 | 27 | 3 | 17256 | 270 |
GAS6,FBXO4,PKIA |
| 8.395e-03 | -4.78 | regulation of endoplasmic reticulum unfolded protein response | biological process | GO:1900101 | 27 | 3 | 17256 | 270 |
DAB2IP,WFS1,ERN1 |
| 8.414e-03 | -4.78 | GSE40666_UNTREATED_VS_IFNA_STIM_STAT4_KO_EFFECTOR_CD8_TCELL_90MIN_DN | MSigDB lists | GSE40666_UNTREATED_VS_IFNA_STIM_STAT4_KO_EFFECTOR_CD8_TCELL_90MIN_DN | 177 | 8 | 17377 | 282 |
SLC30A4,ZHX3,STRADB,MAPK13,PLEKHA1,DISP1,SAV1,SATB1 |
| 8.414e-03 | -4.78 | GSE29618_LAIV_VS_TIV_FLU_VACCINE_DAY7_BCELL_UP | MSigDB lists | GSE29618_LAIV_VS_TIV_FLU_VACCINE_DAY7_BCELL_UP | 177 | 8 | 17377 | 282 |
BDNF,RUNX2,FBXO4,NDRG2,KIF5C,MAPK13,DBP,BARX1 |
| 8.414e-03 | -4.78 | Activin_recp | pfam domains | PF01064 | 9 | 2 | 17054 | 271 |
ACVR2B,ACVR1 |
| 8.527e-03 | -4.76 | V$IK2_01 | MSigDB lists | V$IK2_01 | 253 | 10 | 17377 | 282 |
MN1,BDNF,MSX1,RALGPS2,MAP2K6,TNFSF15,ACVR2B,PRDM1,RNF122,PKIA |
| 8.527e-03 | -4.76 | STK33_NOMO_DN | MSigDB lists | STK33_NOMO_DN | 253 | 10 | 17377 | 282 |
IL17D,SLC40A1,LGR4,ST14,BIK,ZDHHC23,TMEM143,SHISA2,SATB2,NEO1 |
| 8.535e-03 | -4.76 | Activin_recp | interpro domains | IPR000472 | 9 | 2 | 18492 | 296 |
ACVR2B,ACVR1 |
| 8.564e-03 | -4.76 | Body mass index(PMID:20935630) | GWAS genes | Body mass index(PMID:20935630) | 18 | 3 | 2388 | 58 |
BDNF,SLC39A8,QPCTL |
| 8.577e-03 | -4.76 | Negative regulation of activity of TFAP2 (AP-2) family transcription factors | REACTOME pathways | R-HSA-8866904 | 10 | 2 | 10287 | 148 |
KCTD15,KCTD1 |
| 8.588e-03 | -4.76 | haematopoietic_and_lymphoid_tissue-abdomen-lymphoid_neoplasm-follicular_lymphoma | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-abdomen-lymphoid_neoplasm-follicular_lymphoma | 50 | 4 | 17385 | 281 |
ITPR2,SLC30A4,KMO,GPR137C |
| 8.648e-03 | -4.75 | ZHANG_TLX_TARGETS_36HR_UP | MSigDB lists | ZHANG_TLX_TARGETS_36HR_UP | 215 | 9 | 17377 | 282 |
QSOX1,ACSL1,PXN,DUSP8,FBXO4,TNS1,ABHD4,STXBP1,DDIT3 |
| 8.690e-03 | -4.75 | GSE9006_HEALTHY_VS_TYPE_1_DIABETES_PBMC_AT_DX_DN | MSigDB lists | GSE9006_HEALTHY_VS_TYPE_1_DIABETES_PBMC_AT_DX_DN | 178 | 8 | 17377 | 282 |
ACSL1,ST14,MYC,PTPN21,MAFB,SGK1,TNFRSF10C,TLR6 |
| 8.690e-03 | -4.75 | GSE37416_0H_VS_48H_F_TULARENSIS_LVS_NEUTROPHIL_DN | MSigDB lists | GSE37416_0H_VS_48H_F_TULARENSIS_LVS_NEUTROPHIL_DN | 178 | 8 | 17377 | 282 |
PDK1,ALDOA,EFNA3,SLC36A4,PDE4D,SAV1,TANC2,DDIT3 |
| 8.690e-03 | -4.75 | GSE5455_HEALTHY_VS_TUMOR_BEARING_MOUSE_SPLEEN_MONOCYTE_UP | MSigDB lists | GSE5455_HEALTHY_VS_TUMOR_BEARING_MOUSE_SPLEEN_MONOCYTE_UP | 178 | 8 | 17377 | 282 |
ADAMTS3,MPP1,CEBPA,ABAT,TLR6,RNF157,STXBP1,EPDR1 |
| 8.690e-03 | -4.75 | GSE45739_NRAS_KO_VS_WT_ACD3_ACD28_STIM_CD4_TCELL_DN | MSigDB lists | GSE45739_NRAS_KO_VS_WT_ACD3_ACD28_STIM_CD4_TCELL_DN | 178 | 8 | 17377 | 282 |
DACT1,STRADB,SGK1,TMOD2,SMYD3,COBL,PKIA,C3orf67 |
| 8.707e-03 | -4.74 | GO_NAD_METABOLIC_PROCESS | MSigDB lists | GO_NAD_METABOLIC_PROCESS | 50 | 4 | 17377 | 282 |
GAPDH,KMO,ALDOA,HK2 |
| 8.714e-03 | -4.74 | GO_REGULATION_OF_STEM_CELL_DIFFERENTIATION | MSigDB lists | GO_REGULATION_OF_STEM_CELL_DIFFERENTIATION | 109 | 6 | 17377 | 282 |
EPB41L5,PHLDB2,DAB2IP,OVOL2,SAV1,WWTR1 |
| 8.753e-03 | -4.74 | GO_RUFFLE_MEMBRANE | MSigDB lists | GO_RUFFLE_MEMBRANE | 78 | 5 | 17377 | 282 |
WWC1,EPB41L5,FGR,PLEKHA1,SPATA13 |
| 8.753e-03 | -4.74 | MCBRYAN_PUBERTAL_BREAST_4_5WK_UP | MSigDB lists | MCBRYAN_PUBERTAL_BREAST_4_5WK_UP | 254 | 10 | 17377 | 282 |
EPCAM,ST14,PLK2,MAFB,ACTA2,WWC1,GAS6,PALLD,PFN2,PLEKHB1 |
| 8.768e-03 | -4.74 | appendage morphogenesis | biological process | GO:0035107 | 148 | 7 | 17256 | 270 |
B9D1,MSX1,RUNX2,ZNF219,RECK,DLX6,PLXNA2 |
| 8.768e-03 | -4.74 | limb morphogenesis | biological process | GO:0035108 | 148 | 7 | 17256 | 270 |
B9D1,MSX1,RUNX2,ZNF219,RECK,DLX6,PLXNA2 |
| 8.796e-03 | -4.73 | apoptotic process | biological process | GO:0006915 | 910 | 24 | 17256 | 270 |
GAPDH,PDK1,DOCK1,PTPN6,BIK,BNIP3L,NUAK2,GAS6,TNFRSF10C,PRKCA,SAV1,SATB1,TRIB3,PMAIP1,MAP2K6,MYC,PRKCD,ERN1,HK2,SGK1,TNFSF15,DAB2IP,BNIP3,DDIT3 |
| 8.813e-03 | -4.73 | nucleoside diphosphate metabolic process | biological process | GO:0009132 | 81 | 5 | 17256 | 270 |
GAPDH,MPP1,ALDOA,OGDHL,HK2 |
| 8.858e-03 | -4.73 | GO_NEGATIVE_REGULATION_OF_MAPK_CASCADE | MSigDB lists | GO_NEGATIVE_REGULATION_OF_MAPK_CASCADE | 143 | 7 | 17377 | 282 |
NDRG2,DAB2IP,DUSP8,DACT1,PTPN6,MYC,PRKCD |
| 8.868e-03 | -4.73 | positive regulation of protein metabolic process | biological process | GO:0051247 | 1637 | 38 | 17256 | 270 |
LONRF1,ACSL1,ACVR1,NECAB2,FBXO4,CEBPA,GAS6,TNFRSF10C,PRKCA,PFN2,PMAIP1,DACT1,MYC,PRKCD,RASD2,INAVA,DAB2IP,EPHB6,HSPA2,PARP9,ADCY1,EFNA3,WWC1,STRADB,WNT11,GAREM1,PXYLP1,ACVR2B,ARRDC4,TLR6,GPLD1,TRIB3,WFS1,MAP2K6,PLK2,ERN1,TNFSF15,SMYD3 |
| 8.899e-03 | -4.72 | ZBTB25 (zinc finger and BTB domain containing 25) | protein interactions | 7597 | 26 | 3 | 17029 | 283 |
CYP2J2,KCTD1,DDIT3 |
| 8.915e-03 | -4.72 | Ca-dependent events | REACTOME pathways | R-HSA-111996 | 30 | 3 | 10287 | 148 |
PRKCA,PRKCD,ADCY1 |
| 8.944e-03 | -4.72 | GO_REGULATION_OF_HYDROLASE_ACTIVITY | MSigDB lists | GO_REGULATION_OF_HYDROLASE_ACTIVITY | 1272 | 32 | 17377 | 282 |
ARHGAP26,RGS16,RASAL2,ARHGEF11,BVES,DOCK1,RECK,C4A,SPATA13,ARL2,WNT11,GAS6,TBC1D16,PFN2,TIAM2,GPLD1,RGS17,RALGPS2,PMAIP1,RASGRF2,GNAO1,MYC,ERN1,PRKCD,PLEKHG1,SRGAP1,ARHGAP28,DAB2IP,TNFSF15,IQSEC2,HSPA2,TBC1D8 |
| 8.972e-03 | -4.71 | GSE17186_BLOOD_VS_CORD_BLOOD_NAIVE_BCELL_DN | MSigDB lists | GSE17186_BLOOD_VS_CORD_BLOOD_NAIVE_BCELL_DN | 179 | 8 | 17377 | 282 |
RALGPS2,ZHX3,KIAA0355,FBXO4,BACE1,SPATA13,NDRG2,SMPDL3A |
| 8.972e-03 | -4.71 | GSE37605_C57BL6_VS_NOD_FOXP3_FUSION_GFP_TREG_DN | MSigDB lists | GSE37605_C57BL6_VS_NOD_FOXP3_FUSION_GFP_TREG_DN | 179 | 8 | 17377 | 282 |
PLK2,MYC,ATOX1,NUAK2,RASL11B,PDE4D,HSPA2,TBC1D8 |
| 9.014e-03 | -4.71 | TORCHIA_TARGETS_OF_EWSR1_FLI1_FUSION_DN | MSigDB lists | TORCHIA_TARGETS_OF_EWSR1_FLI1_FUSION_DN | 295 | 11 | 17377 | 282 |
IFT81,RALGPS2,SLC39A8,HK2,PLXNA2,CCDC122,ARRDC4,SATB1,SMYD3,KCTD1,RERE |
| 9.014e-03 | -4.71 | GO_REGULATION_OF_ACTIN_FILAMENT_BASED_PROCESS | MSigDB lists | GO_REGULATION_OF_ACTIN_FILAMENT_BASED_PROCESS | 295 | 11 | 17377 | 282 |
PPM1E,SCN5A,PHLDB2,DSTN,PRKCD,TMOD2,WNT11,PDE4D,PFN2,JAM3,FHOD3 |
| 9.054e-03 | -4.70 | SENESE_HDAC3_TARGETS_UP | MSigDB lists | SENESE_HDAC3_TARGETS_UP | 464 | 15 | 17377 | 282 |
PHLDB2,RGS16,CCDC148,SCAMP1,ZNF697,PMAIP1,UBASH3B,CYB5R2,SHISA2,TNFSF15,PRDM1,FAM198B,NCEH1,SAV1,PKIA |
| 9.095e-03 | -4.70 | LEE_NEURAL_CREST_STEM_CELL_DN | MSigDB lists | LEE_NEURAL_CREST_STEM_CELL_DN | 110 | 6 | 17377 | 282 |
GAS6,PALLD,PMAIP1,PLK2,PLEKHB1,MTUS1 |
| 9.095e-03 | -4.70 | REACTOME_SIGNALING_BY_RHO_GTPASES | MSigDB lists | REACTOME_SIGNALING_BY_RHO_GTPASES | 110 | 6 | 17377 | 282 |
ARHGAP28,ARHGAP26,ARHGEF11,RASGRF2,TIAM2,SRGAP1 |
| 9.099e-03 | -4.70 | Human Thyroid Stimulating Hormone (TSH) signaling pathway | WikiPathways | WP2032 | 68 | 5 | 5312 | 101 |
PDE4D,TSHR,MAP2K6,GNAO1,MYC |
| 9.136e-03 | -4.70 | divalent inorganic cation transmembrane transporter activity | molecular function | GO:0072509 | 27 | 3 | 17224 | 278 |
SLC40A1,SLC30A4,SLC39A8 |
| 9.137e-03 | -4.70 | CSK (C-terminal Src kinase) | protein interactions | 1445 | 77 | 5 | 17029 | 283 |
TNS1,RGS16,FGR,PXN,UBASH3B |
| 9.137e-03 | -4.70 | ATF4 (activating transcription factor 4) | protein interactions | 468 | 77 | 5 | 17029 | 283 |
MAFB,TRIB3,CEBPA,DDIT3,GTF2F2 |
| 9.173e-03 | -4.69 | JSRP1 (junctional sarcoplasmic reticulum protein 1) | protein interactions | 126306 | 9 | 2 | 17029 | 283 |
PRKCA,GNAO1 |
| 9.173e-03 | -4.69 | KRTAP13-1 (keratin associated protein 13-1) | protein interactions | 140258 | 9 | 2 | 17029 | 283 |
LONRF1,SCAMP1 |
| 9.173e-03 | -4.69 | WWC3 (WWC family member 3) | protein interactions | 55841 | 9 | 2 | 17029 | 283 |
WWC1,PRKCA |
| 9.173e-03 | -4.69 | Plk2 (polo like kinase 2) | protein interactions | 20620 | 9 | 2 | 17029 | 283 |
STXBP1,PLK2 |
| 9.185e-03 | -4.69 | GSE4590_SMALL_VS_LARGE_PRE_BCELL_DN | MSigDB lists | GSE4590_SMALL_VS_LARGE_PRE_BCELL_DN | 144 | 7 | 17377 | 282 |
ARHGAP26,EPCAM,PRSS16,PMAIP1,MARVELD2,CAPN5,SMPDL3A |
| 9.185e-03 | -4.69 | GO_CELLULAR_RESPONSE_TO_INORGANIC_SUBSTANCE | MSigDB lists | GO_CELLULAR_RESPONSE_TO_INORGANIC_SUBSTANCE | 144 | 7 | 17377 | 282 |
BNIP3,CPNE2,SCN5A,CEBPA,SLC40A1,GPLD1,ADCY1 |
| 9.220e-03 | -4.69 | ROZANOV_MMP14_TARGETS_UP | MSigDB lists | ROZANOV_MMP14_TARGETS_UP | 256 | 10 | 17377 | 282 |
IQCK,MSX1,PMAIP1,DSTN,PLK2,RBPMS2,BACE1,EMILIN2,LHPP,ARRDC4 |
| 9.223e-03 | -4.69 | TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_6HR_UP | MSigDB lists | TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_6HR_UP | 79 | 5 | 17377 | 282 |
SHISA2,MSX1,FAM198B,DLX2,KMO |
| 9.235e-03 | -4.68 | GO_CELL_LEADING_EDGE | MSigDB lists | GO_CELL_LEADING_EDGE | 337 | 12 | 17377 | 282 |
EPB41L5,PHLDB2,FGR,PXN,SPATA13,WWC1,ACTA2,PLEKHA1,PALLD,TLN2,COBL,TIAM2 |
| 9.262e-03 | -4.68 | E2F1_UP.V1_DN | MSigDB lists | E2F1_UP.V1_DN | 180 | 8 | 17377 | 282 |
TRIB3,RUNX2,SCAMP1,PLK2,MYC,SGK1,ITPR2,TSHR |
| 9.262e-03 | -4.68 | GSE15330_HSC_VS_PRO_BCELL_DN | MSigDB lists | GSE15330_HSC_VS_PRO_BCELL_DN | 180 | 8 | 17377 | 282 |
B9D1,NUMBL,MXI1,NECAB2,DACT1,TMEM143,SMPDL3A,PARP9 |
| 9.273e-03 | -4.68 | GO_REGULATION_OF_CATENIN_IMPORT_INTO_NUCLEUS | MSigDB lists | GO_REGULATION_OF_CATENIN_IMPORT_INTO_NUCLEUS | 27 | 3 | 17377 | 282 |
DAB2IP,DACT1,WWTR1 |
| 9.273e-03 | -4.68 | GO_HIPPO_SIGNALING | MSigDB lists | GO_HIPPO_SIGNALING | 27 | 3 | 17377 | 282 |
WWC1,SAV1,WWTR1 |
| 9.273e-03 | -4.68 | GO_POSITIVE_REGULATION_OF_RELEASE_OF_CYTOCHROME_C_FROM_MITOCHONDRIA | MSigDB lists | GO_POSITIVE_REGULATION_OF_RELEASE_OF_CYTOCHROME_C_FROM_MITOCHONDRIA | 27 | 3 | 17377 | 282 |
BNIP3,PMAIP1,BIK |
| 9.291e-03 | -4.68 | ABHYDROLASE | prints domains | PR00111 | 10 | 2 | 4652 | 70 |
ABHD4,ABHD6 |
| 9.295e-03 | -4.68 | brown fat cell differentiation | biological process | GO:0050873 | 28 | 3 | 17256 | 270 |
BNIP3,CEBPA,ZNF516 |
| 9.313e-03 | -4.68 | regulation of protein modification process | biological process | GO:0031399 | 1804 | 41 | 17256 | 270 |
ACSL1,ACVR1,NECAB2,DUSP8,FBXO4,UBASH3B,NDRG2,CEBPA,GAS6,TNFRSF10C,PRKCA,PFN2,PPM1E,DACT1,MYC,PRKCD,RASD2,INAVA,DAB2IP,PDE4D,EPHB6,HSPA2,PARP9,PTPN6,ADCY1,WWC1,STRADB,WNT11,GAREM1,ACVR2B,ARRDC4,TLR6,TRIB3,FGR,MAP2K6,WFS1,WWTR1,ERN1,TNFSF15,SMYD3,PKIA |
| 9.330e-03 | -4.67 | MODULE_329 | MSigDB lists | MODULE_329 | 51 | 4 | 17377 | 282 |
ACTA2,MYOM2,SCN5A,ALDOA |
| 9.367e-03 | -4.67 | GO_REGULATION_OF_CELLULAR_COMPONENT_MOVEMENT | MSigDB lists | GO_REGULATION_OF_CELLULAR_COMPONENT_MOVEMENT | 739 | 21 | 17377 | 282 |
EPB41L5,SCN5A,PHLDB2,ACVR1,RECK,MPP1,SPATA13,PLXNA2,WNT11,GAS6,PRKCA,ABHD6,PFN2,JAM3,GPLD1,EPCAM,FGR,SRGAP1,SGK1,DAB2IP,PDE4D |
| 9.415e-03 | -4.67 | negative regulation of actin filament polymerization | biological process | GO:0030837 | 53 | 4 | 17256 | 270 |
TMOD2,PFN2,PRKCD,FHOD3 |
| 9.421e-03 | -4.66 | large_intestine-caecum-carcinoma-adenocarcinoma | COSMIC cancer mutations | large_intestine-caecum-carcinoma-adenocarcinoma | 14652 | 251 | 17385 | 281 |
ARHGAP26,CCDC126,ACSL1,ACVR1,DUSP8,LGR4,RECK,HEBP1,LSM11,PTPN21,NDRG2,CEBPA,SLC2A13,ITPR2,ABAT,PRKCA,ABHD4,CACNB4,ABHD6,HMCN1,NCS1,EPDR1,EPCAM,CPNE2,FKBP9,PPM1E,DLX6,MARVELD2,CFHR1,TMEM143,TMEM37,TLN2,OR2W3,TSHR,FANK1,TBC1D8,PGBD5,ZNF391,PNRC1,KLHL23,KLHL3,WISP3,EXOC6B,DSTN,CAPN5,SLC25A28,TTC22,ABCC2,TNS1,ACVR2B,SGK2,SAV1,NT5DC2,PLEKHB1,SPNS1,DYRK1B,SPATA9,TCF7L1,PLK2,RASGRF2,ERN1,ALDOA,ARHGAP28,MAPK13,TMOD2,DLX2,TANC2,APBA2,LONRF1,SCN5A,RGS16,TMEM63C,RUNX2,ZNF395,ZHX3,BVES,UBASH3B,FBXO4,CYP4V2,SETBP1,RASL11B,ATP6V1E2,CHADL,SLC36A4,TNFRSF10C,PFN2,SATB1,DYNC1I1,HPCAL4,NIPSNAP3B,FHOD3,MTUS1,IL17D,NUMBL,RALGPS2,SLC30A4,MYC,ZIC5,EBF4,SRGAP1,GAN,NCEH1,MOXD1,VGLL4,STXBP1,BARX1,GPR161,EPB41L5,BDNF,IL17RD,QSOX1,SPATA13,PPFIA4,WDR25,WWC1,STRADB,MAFB,SHISA2,PRDM1,LHPP,ARRDC4,OR11H4,B4GALNT3,ZNF558,KIAA0355,ADAMTS3,ISM1,LRRIQ3,QPCTL,EMILIN2,HK2,CLMN,IQSEC2,RNF122,SMYD3,ZNF516,RASAL2,DOCK1,ST14,C4A,FAM131C,CCDC110,PLXNA2,RHPN2,FAM198B,COLEC10,KIF21B,RADIL,CBLN1,TIAM2,TMEM53,ZNF827,KCTD15,KMO,DACT1,RPS6KL1,ZNF521,EEPD1,ZDHHC23,MAP7,DAB2IP,MYH15,PJA1,PDE4D,DNAH5,FAM78B,KIAA1549,HSPA2,C3orf67,DZANK1,PHLDB2,GAPDH,UROS,PDK1,SLC39A8,SOX21,PTPN6,SFXN4,ADCY1,NLGN4X,SATB2,WNT11,RAB38,TBC1D16,JAM3,CENPV,IFT81,LMLN,WFS1,WWTR1,PLEKHG1,P4HA1,TNFSF15,DISP1,DBP,KLHL31,COBL,KCTD1,CCDC148,MXI1,TMEM132C,NECAB2,PRSS16,ARHGEF11,BACE1,BIK,BLVRB,KIF5C,ARL2,OVOL2,ZNF219,NEO1,RGS17,GPR155,PRKCD,EHD3,RASD2,CCDC122,TRIM3,PRICKLE2,SGK1,KIAA0408,PARP9,TMC7,MN1,B9D1,SLC40A1,MSX1,PXN,MPP1,OGDHL,NUAK2,PALLD,EXOG,TLR6,RERE,GPLD1,CTIF,TRIB3,FGR,GNAO1,FMO4,KIAA0513,ZNF474,MYOM2,THAP10,RNF157,PKIA,DDIT3,B4GALT7,PHC1 |
| 9.481e-03 | -4.66 | regulation of phosphorus metabolic process | biological process | GO:0051174 | 1806 | 41 | 17256 | 270 |
ACSL1,ACVR1,NECAB2,DUSP8,UBASH3B,NDRG2,CEBPA,GAS6,TNFRSF10C,PRKCA,PFN2,PPM1E,DACT1,MYC,PRKCD,INAVA,DAB2IP,PDE4D,EPHB6,TSHR,HSPA2,GPR161,PARP9,PDK1,PTPN6,ADCY1,WWC1,STRADB,WNT11,GAREM1,ACVR2B,TLR6,GPLD1,TRIB3,FGR,MAP2K6,WWTR1,ERN1,TNFSF15,SMYD3,PKIA |
| 9.494e-03 | -4.66 | positive regulation of signaling | biological process | GO:0023056 | 1752 | 40 | 17256 | 270 |
ACVR1,NECAB2,LGR4,BVES,BIK,GAS6,TNFRSF10C,ABAT,PRKCA,MYORG,NEO1,PMAIP1,KMO,DACT1,PRKCD,RASD2,INAVA,DAB2IP,BNIP3,EPHB6,STXBP1,PARP9,BDNF,MSX1,PTPN6,WWC1,WNT11,GAREM1,ACVR2B,TLR6,GPLD1,FGR,ADAMTS3,MAP2K6,PLK2,ERN1,TNFSF15,TMOD2,DISP1,DDIT3 |
| 9.558e-03 | -4.65 | GSE8835_CD4_VS_CD8_TCELL_CLL_PATIENT_DN | MSigDB lists | GSE8835_CD4_VS_CD8_TCELL_CLL_PATIENT_DN | 181 | 8 | 17377 | 282 |
B9D1,SLC30A4,MARVELD2,CYP2J2,DAB2IP,RNF122,TBC1D16,TBC1D8 |
| 9.558e-03 | -4.65 | GSE34156_NOD2_LIGAND_VS_TLR1_TLR2_LIGAND_6H_TREATED_MONOCYTE_DN | MSigDB lists | GSE34156_NOD2_LIGAND_VS_TLR1_TLR2_LIGAND_6H_TREATED_MONOCYTE_DN | 181 | 8 | 17377 | 282 |
MAFB,QSOX1,FAM198B,ACSL1,ZNF697,MPP1,BLVRB,EMILIN2 |
| 9.558e-03 | -4.65 | GSE22886_NAIVE_TCELL_VS_MONOCYTE_UP | MSigDB lists | GSE22886_NAIVE_TCELL_VS_MONOCYTE_UP | 181 | 8 | 17377 | 282 |
BNIP3,PJA1,KIF21B,PRKCA,SATB1,SMYD3,PLEKHB1,PKIA |
| 9.558e-03 | -4.65 | GSE3982_BCELL_VS_TH2_DN | MSigDB lists | GSE3982_BCELL_VS_TH2_DN | 181 | 8 | 17377 | 282 |
GPR63,BDNF,KLHL23,MPP1,MAP7,RAB38,PALLD,NCS1 |
| 9.566e-03 | -4.65 | Interactions of neurexins and neuroligins at synapses | REACTOME pathways | R-HSA-6794361 | 58 | 4 | 10287 | 148 |
NLGN4X,EPB41L5,APBA2,STXBP1 |
| 9.602e-03 | -4.65 | axon | cellular component | GO:0030424 | 540 | 16 | 18223 | 280 |
BDNF,NECAB2,BACE1,C4A,BLVRB,NDRG2,KIF5C,KIF21B,PALLD,PFN2,TIAM2,NCS1,TMOD2,DAB2IP,STXBP1,COBL |
| 9.643e-03 | -4.64 | MODULE_459 | MSigDB lists | MODULE_459 | 381 | 13 | 17377 | 282 |
SPNS1,ACVR1,ACSL1,MAP2K6,PLEKHG1,WDR25,PRDM1,PDE4D,EPHB6,SAV1,CBLN1,PKIA,RERE |
| 9.655e-03 | -4.64 | KRIGE_RESPONSE_TO_TOSEDOSTAT_6HR_UP | MSigDB lists | KRIGE_RESPONSE_TO_TOSEDOSTAT_6HR_UP | 836 | 23 | 17377 | 282 |
RGS16,ACSL1,SCAMP1,RECK,SFXN4,BLVRB,ATOX1,BNIP3L,MAFB,SHISA2,SLC36A4,ITPR2,PLEKHA1,KIF21B,ARRDC4,PRKCA,TRIB3,PMAIP1,KIAA0355,TMEM143,MAP7,PDE4D,NCEH1 |
| 9.670e-03 | -4.64 | human chr20q12 | chromosome location | human chr20q12 | 12 | 2 | 26185 | 331 |
MAFB,ZHX3 |
| 9.689e-03 | -4.64 | GRAESSMANN_APOPTOSIS_BY_SERUM_DEPRIVATION_DN | MSigDB lists | GRAESSMANN_APOPTOSIS_BY_SERUM_DEPRIVATION_DN | 219 | 9 | 17377 | 282 |
BNIP3,LHPP,PDK1,RAB27B,PRKCA,PFN2,ABHD6,CAPN5,SPATA13 |
| 9.711e-03 | -4.63 | GO_NUCLEOSIDE_DIPHOSPHATE_METABOLIC_PROCESS | MSigDB lists | GO_NUCLEOSIDE_DIPHOSPHATE_METABOLIC_PROCESS | 80 | 5 | 17377 | 282 |
GAPDH,MPP1,ALDOA,OGDHL,HK2 |
| 9.711e-03 | -4.63 | GO_REGULATION_OF_FIBROBLAST_PROLIFERATION | MSigDB lists | GO_REGULATION_OF_FIBROBLAST_PROLIFERATION | 80 | 5 | 17377 | 282 |
DAB2IP,GAS6,PMAIP1,MYC,B4GALT7 |
| 9.722e-03 | -4.63 | BCL2L1 (BCL2 like 1) | protein interactions | 598 | 109 | 6 | 17029 | 283 |
SPNS1,BNIP3,ZNF219,PMAIP1,BIK,BNIP3L |
| 9.723e-03 | -4.63 | large_intestine-carcinoma-adenocarcinoma | COSMIC cancer mutations | large_intestine-carcinoma-adenocarcinoma | 16678 | 277 | 17385 | 281 |
ARHGAP26,ACVR1,DUSP8,LGR4,RECK,LSM11,ALG1L,CEBPA,PRKCA,ABHD6,NCS1,EPDR1,PMAIP1,CFHR1,TMEM37,TSHR,TBC1D8,KLHL23,KLHL3,WISP3,EXOC6B,DSTN,BNIP3L,SLC25A28,ABCC2,TNS1,ACVR2B,SAV1,SPATA9,PLK2,RASGRF2,ALDOA,ARHGAP28,MAPK13,TMOD2,TANC2,SCN5A,TMEM63C,ZHX3,CYP2J2,SLC36A4,TNFRSF10C,DYNC1I1,HPCAL4,NIPSNAP3B,MTUS1,IL17D,RALGPS2,MYC,ZIC5,SRGAP1,MOXD1,STXBP1,GPR161,EPB41L5,BDNF,QSOX1,SHISA2,ARRDC4,OR11H4,ZNF558,ADAMTS3,ISM1,LRRIQ3,QPCTL,EMILIN2,CLMN,IQSEC2,SMYD3,ZNF516,RASAL2,ST14,FAM131C,C4A,CCDC110,PLXNA2,COLEC10,TIAM2,TMEM53,ZNF827,KMO,DACT1,DAB2IP,PJA1,PDE4D,RAB27B,DNAH5,ATP6AP1L,C3orf67,DZANK1,GAPDH,PDK1,SOX21,CYB5R2,SFXN4,ADCY1,NLGN4X,SATB2,WNT11,RAB38,TBC1D16,TRIQK,IQCK,WFS1,WWTR1,PLEKHG1,P4HA1,TNFSF15,DBP,KLHL31,COBL,KCTD1,C2orf88,CCDC148,MXI1,TMEM132C,BACE1,BIK,CCNJL,KIF5C,ARL2,GAS6,ZNF219,NEO1,RGS17,GPR155,SMPDL3A,PARP9,TMC7,MN1,B9D1,SLC40A1,PXN,MPP1,GPR137C,GPLD1,TRIB3,FGR,GNAO1,MYOM2,TNFRSF17,DDIT3,B4GALT7,PHC1,CCDC126,ACSL1,HEBP1,PTPN21,NDRG2,NRN1,ABAT,ITPR2,SLC2A13,CACNB4,ABHD4,HMCN1,EPCAM,PPM1E,FKBP9,CPNE2,MARVELD2,DLX6,TMEM143,TLN2,FANK1,OR2W3,ZNF391,PGBD5,PNRC1,CAPN5,ATOX1,TTC22,PLEKHA1,SGK2,NT5DC2,PLEKHB1,DYRK1B,SPNS1,TCF7L1,ERN1,DLX2,APBA2,GPR63,LONRF1,RGS16,RUNX2,ZNF395,BVES,FBXO4,UBASH3B,CYP4V2,ATP6V1E2,RASL11B,SETBP1,CHADL,SATB1,PFN2,FHOD3,NUMBL,SLC30A4,GAN,EBF4,BNIP3,NCEH1,VGLL4,BARX1,IL17RD,SPATA13,EFNA3,MAFB,STRADB,WWC1,WDR25,PPFIA4,LHPP,PRDM1,B4GALNT3,KIAA0355,HK2,RNF122,DOCK1,RHPN2,FAM198B,KIF21B,RADIL,CBLN1,KCTD15,RPS6KL1,EEPD1,ZDHHC23,ZNF521,MAP7,MYH15,TMEM120B,HSPA2,FAM78B,PHLDB2,UROS,SLC39A8,PTPN6,JAM3,CENPV,IFT81,LMLN,ANKRD31,RBPMS2,DISP1,NECAB2,PRSS16,ARHGEF11,BLVRB,OVOL2,PRKCD,RASD2,EHD3,GTF2F2,ACTA2,PRICKLE2,TRIM3,SGK1,CCDC122,KIAA0408,MSX1,NUAK2,OGDHL,EXOG,PALLD,TLR6,CTIF,RERE,FMO4,MAP2K6,KIAA0513,ZNF474,THAP10,RNF157,PKIA |
| 9.723e-03 | -4.63 | protein kinase activity | molecular function | GO:0004672 | 652 | 19 | 17224 | 278 |
ACVR1,PDK1,NUAK2,EFNA3,STRADB,ACVR2B,SGK2,PRKCA,GRK3,DYRK1B,FGR,MAP2K6,PLK2,RPS6KL1,PRKCD,ERN1,SGK1,MAPK13,EPHB6 |
| 9.740e-03 | -4.63 | kidney morphogenesis | biological process | GO:0060993 | 83 | 5 | 17256 | 270 |
WNT11,LGR4,KLHL3,MYC,WWTR1 |
| 9.759e-03 | -4.63 | CatSper complex | cellular component | GO:0036128 | 10 | 2 | 18223 | 280 |
CATSPERE,HSPA2 |
| 9.840e-03 | -4.62 | pyridine-containing compound metabolic process | biological process | GO:0072524 | 116 | 6 | 17256 | 270 |
GAPDH,KMO,ALDOA,PARP9,OGDHL,HK2 |
| 9.842e-03 | -4.62 | GO_ACTIVATION_OF_IMMUNE_RESPONSE | MSigDB lists | GO_ACTIVATION_OF_IMMUNE_RESPONSE | 382 | 13 | 17377 | 282 |
FGR,DOCK1,CFHR1,C4A,MAP2K6,PTPN6,PRKCD,PDE4D,PLEKHA1,COLEC10,TLR6,CACNB4,GPLD1 |
| 9.862e-03 | -4.62 | GSE30971_CTRL_VS_LPS_STIM_MACROPHAGE_WBP7_KO_2H_DN | MSigDB lists | GSE30971_CTRL_VS_LPS_STIM_MACROPHAGE_WBP7_KO_2H_DN | 182 | 8 | 17377 | 282 |
KIAA0513,DISP1,NCEH1,ABHD6,MPP1,UBASH3B,BLVRB,EEPD1 |
| 9.862e-03 | -4.62 | GSE40274_LEF1_VS_FOXP3_AND_LEF1_TRANSDUCED_ACTIVATED_CD4_TCELL_DN | MSigDB lists | GSE40274_LEF1_VS_FOXP3_AND_LEF1_TRANSDUCED_ACTIVATED_CD4_TCELL_DN | 182 | 8 | 17377 | 282 |
PDK1,EHD3,WWTR1,SGK1,RNF122,TBC1D16,SATB1,B4GALT7 |
| 9.862e-03 | -4.62 | GSE36476_CTRL_VS_TSST_ACT_72H_MEMORY_CD4_TCELL_YOUNG_UP | MSigDB lists | GSE36476_CTRL_VS_TSST_ACT_72H_MEMORY_CD4_TCELL_YOUNG_UP | 182 | 8 | 17377 | 282 |
MXI1,PXN,SGK1,KIAA0513,PFN2,APBA2,JAM3,PHC1 |
| 9.862e-03 | -4.62 | GSE19198_CTRL_VS_IL21_TREATED_TCELL_6H_UP | MSigDB lists | GSE19198_CTRL_VS_IL21_TREATED_TCELL_6H_UP | 182 | 8 | 17377 | 282 |
UROS,MPP1,SFXN4,MYC,BLVRB,EMILIN2,ARL2,TMOD2 |
| 9.862e-03 | -4.62 | GSE3982_BCELL_VS_NKCELL_UP | MSigDB lists | GSE3982_BCELL_VS_NKCELL_UP | 182 | 8 | 17377 | 282 |
PPM1E,EHD3,BIK,HK2,GTF2F2,SAV1,TSHR,B4GALT7 |
| 9.862e-03 | -4.62 | STARK_PREFRONTAL_CORTEX_22Q11_DELETION_UP | MSigDB lists | STARK_PREFRONTAL_CORTEX_22Q11_DELETION_UP | 182 | 8 | 17377 | 282 |
NUMBL,LSM11,EHD3,KIF5C,KIAA0513,TMOD2,DAB2IP,NCS1 |
| 9.862e-03 | -4.62 | GSE21670_UNTREATED_VS_TGFB_TREATED_CD4_TCELL_DN | MSigDB lists | GSE21670_UNTREATED_VS_TGFB_TREATED_CD4_TCELL_DN | 182 | 8 | 17377 | 282 |
TRIB3,SFXN4,UBASH3B,EXOC6B,RAB38,EPHB6,PALLD,PHC1 |
| 9.867e-03 | -4.62 | V$OCT1_07 | MSigDB lists | V$OCT1_07 | 146 | 7 | 17377 | 282 |
PRICKLE2,BDNF,WNT11,TMOD2,RALGPS2,NEO1,MTUS1 |
| 9.905e-03 | -4.61 | HTHREPRESSR | prints domains | PR00031 | 30 | 3 | 4652 | 70 |
DLX2,BARX1,DLX6 |
| 9.908e-03 | -4.61 | MORF_ERCC4 | MSigDB lists | MORF_ERCC4 | 299 | 11 | 17377 | 282 |
IQCK,PPM1E,RUNX2,SCAMP1,DOCK1,EXOC6B,PDE4D,TANC2,PRKCA,PLEKHB1,GPLD1 |
| 9.978e-03 | -4.61 | 4-aminobutyrate degradation | BIOCYC pathways | HUMAN_PWY-6535 | 1 | 1 | 902 | 9 |
ABAT |
| 9.978e-03 | -4.61 | 4-aminobutanoate degradation I | BIOCYC pathways | META_PWY-6535 | 1 | 1 | 902 | 9 |
ABAT |
| 9.982e-03 | -4.61 | REACTOME_PHOSPHOLIPASE_C_MEDIATED_CASCADE | MSigDB lists | REACTOME_PHOSPHOLIPASE_C_MEDIATED_CASCADE | 52 | 4 | 17377 | 282 |
ITPR2,PRKCA,PRKCD,ADCY1 |
| 1.002e-02 | -4.60 | GO_PHOSPHORYLATION | MSigDB lists | GO_PHOSPHORYLATION | 1182 | 30 | 17377 | 282 |
IL17RD,GAPDH,ACVR1,PDK1,RASAL2,PTPN6,OGDHL,NUAK2,STRADB,WNT11,ACVR2B,GAS6,PRKCA,SGK2,DYRK1B,TRIB3,FGR,MAP2K6,RPS6KL1,MYC,PLK2,RASGRF2,ALDOA,PRKCD,ERN1,HK2,SGK1,MAPK13,DAB2IP,EPHB6 |
| 1.005e-02 | -4.60 | GO_CHEMICAL_HOMEOSTASIS | MSigDB lists | GO_CHEMICAL_HOMEOSTASIS | 839 | 23 | 17377 | 282 |
SLC40A1,KLHL3,SFXN4,SLC39A8,ATOX1,ADCY1,ATP6V1E2,CEBPA,ABCC2,SLC25A28,ITPR2,GAS6,RAB38,SGK2,CACNB4,NEO1,SLC30A4,WFS1,MYC,ERN1,HK2,SGK1,DDIT3 |
| 1.010e-02 | -4.59 | foregut morphogenesis | biological process | GO:0007440 | 10 | 2 | 17256 | 270 |
EPB41L5,ACVR2B |
| 1.010e-02 | -4.59 | positive regulation of glutamate secretion | biological process | GO:0014049 | 10 | 2 | 17256 | 270 |
KMO,STXBP1 |
| 1.010e-02 | -4.59 | actin filament network formation | biological process | GO:0051639 | 10 | 2 | 17256 | 270 |
COBL,FHOD3 |
| 1.013e-02 | -4.59 | ZWANG_TRANSIENTLY_UP_BY_1ST_EGF_PULSE_ONLY | MSigDB lists | ZWANG_TRANSIENTLY_UP_BY_1ST_EGF_PULSE_ONLY | 1539 | 37 | 17377 | 282 |
CCDC148,RASAL2,BVES,RECK,BLVRB,PLXNA2,SETBP1,NRN1,OVOL2,ZNF219,ABHD4,MTUS1,GAN,ACTA2,DAB2IP,PDE4D,FANK1,PARP9,MN1,PHLDB2,BDNF,PNRC1,EXOC6B,BNIP3L,NUAK2,MAFB,LHPP,PLEKHA1,IFT81,LMLN,IGIP,MAP2K6,HK2,CLMN,TMOD2,MYOM2,TANC2 |
| 1.017e-02 | -4.59 | GSE22886_NAIVE_VS_IGG_IGA_MEMORY_BCELL_UP | MSigDB lists | GSE22886_NAIVE_VS_IGG_IGA_MEMORY_BCELL_UP | 183 | 8 | 17377 | 282 |
SLC30A4,KMO,HEBP1,PLEKHA1,EXOG,SATB1,ABHD4,PHC1 |
| 1.017e-02 | -4.59 | GSE30971_2H_VS_4H_LPS_STIM_MACROPHAGE_WBP7_KO_UP | MSigDB lists | GSE30971_2H_VS_4H_LPS_STIM_MACROPHAGE_WBP7_KO_UP | 183 | 8 | 17377 | 282 |
GPR63,CCDC126,TCF7L1,MSX1,DUSP8,EBF4,DBP,EXOG |
| 1.017e-02 | -4.59 | GSE3982_MAST_CELL_VS_MAC_UP | MSigDB lists | GSE3982_MAST_CELL_VS_MAC_UP | 183 | 8 | 17377 | 282 |
ADAMTS3,PDE4D,KIF21B,ABHD6,SMYD3,HSPA2,PGBD5,RERE |
| 1.017e-02 | -4.59 | GSE10325_LUPUS_CD4_TCELL_VS_LUPUS_MYELOID_UP | MSigDB lists | GSE10325_LUPUS_CD4_TCELL_VS_LUPUS_MYELOID_UP | 183 | 8 | 17377 | 282 |
KLHL3,KIAA0355,PJA1,PRKCA,KIF21B,PKIA,PLEKHB1,PHC1 |
| 1.017e-02 | -4.59 | GSE40685_NAIVE_CD4_TCELL_VS_TREG_DN | MSigDB lists | GSE40685_NAIVE_CD4_TCELL_VS_TREG_DN | 183 | 8 | 17377 | 282 |
CCDC126,LGR4,ZNF697,CYP4V2,ITPR2,DLX2,SMYD3,PARP9 |
| 1.022e-02 | -4.58 | caecum | COSMIC cancer mutations | caecum | 14664 | 251 | 17385 | 281 |
ARHGAP26,CCDC126,ACSL1,ACVR1,DUSP8,LGR4,RECK,HEBP1,LSM11,PTPN21,NDRG2,CEBPA,SLC2A13,ITPR2,ABAT,PRKCA,ABHD4,CACNB4,ABHD6,HMCN1,NCS1,EPDR1,EPCAM,CPNE2,FKBP9,PPM1E,DLX6,MARVELD2,CFHR1,TMEM143,TMEM37,TLN2,OR2W3,TSHR,FANK1,TBC1D8,PGBD5,ZNF391,PNRC1,KLHL23,KLHL3,WISP3,EXOC6B,DSTN,CAPN5,SLC25A28,TTC22,ABCC2,TNS1,ACVR2B,SGK2,SAV1,NT5DC2,PLEKHB1,SPNS1,DYRK1B,SPATA9,TCF7L1,PLK2,RASGRF2,ERN1,ALDOA,ARHGAP28,MAPK13,TMOD2,DLX2,TANC2,APBA2,LONRF1,SCN5A,RGS16,TMEM63C,RUNX2,ZNF395,ZHX3,BVES,UBASH3B,FBXO4,CYP4V2,SETBP1,RASL11B,ATP6V1E2,CHADL,SLC36A4,TNFRSF10C,PFN2,SATB1,DYNC1I1,HPCAL4,NIPSNAP3B,FHOD3,MTUS1,IL17D,NUMBL,RALGPS2,SLC30A4,MYC,ZIC5,EBF4,SRGAP1,GAN,NCEH1,MOXD1,VGLL4,STXBP1,BARX1,GPR161,EPB41L5,BDNF,IL17RD,QSOX1,SPATA13,PPFIA4,WDR25,WWC1,STRADB,MAFB,SHISA2,PRDM1,LHPP,ARRDC4,OR11H4,B4GALNT3,ZNF558,KIAA0355,ADAMTS3,ISM1,LRRIQ3,QPCTL,EMILIN2,HK2,CLMN,IQSEC2,RNF122,SMYD3,ZNF516,RASAL2,DOCK1,ST14,C4A,FAM131C,CCDC110,PLXNA2,RHPN2,FAM198B,COLEC10,KIF21B,RADIL,CBLN1,TIAM2,TMEM53,ZNF827,KCTD15,KMO,DACT1,RPS6KL1,ZNF521,EEPD1,ZDHHC23,MAP7,DAB2IP,MYH15,PJA1,PDE4D,DNAH5,FAM78B,KIAA1549,HSPA2,C3orf67,DZANK1,PHLDB2,GAPDH,UROS,PDK1,SLC39A8,SOX21,PTPN6,SFXN4,ADCY1,NLGN4X,SATB2,WNT11,RAB38,TBC1D16,JAM3,CENPV,IFT81,LMLN,WFS1,WWTR1,PLEKHG1,P4HA1,TNFSF15,DISP1,DBP,KLHL31,COBL,KCTD1,CCDC148,MXI1,TMEM132C,NECAB2,PRSS16,ARHGEF11,BACE1,BIK,BLVRB,KIF5C,ARL2,OVOL2,ZNF219,NEO1,RGS17,GPR155,PRKCD,EHD3,RASD2,CCDC122,TRIM3,PRICKLE2,SGK1,KIAA0408,PARP9,TMC7,MN1,B9D1,SLC40A1,MSX1,PXN,MPP1,OGDHL,NUAK2,PALLD,EXOG,TLR6,RERE,GPLD1,CTIF,TRIB3,FGR,GNAO1,FMO4,KIAA0513,ZNF474,MYOM2,THAP10,RNF157,PKIA,DDIT3,B4GALT7,PHC1 |
| 1.023e-02 | -4.58 | regulation of anion transport | biological process | GO:0044070 | 84 | 5 | 17256 | 270 |
ABAT,KMO,STXBP1,MAP2K6,PRKCD |
| 1.025e-02 | -4.58 | glucose catabolic process | biological process | GO:0006007 | 29 | 3 | 17256 | 270 |
GAPDH,ALDOA,HK2 |
| 1.025e-02 | -4.58 | positive regulation of G-protein coupled receptor protein signaling pathway | biological process | GO:0045745 | 29 | 3 | 17256 | 270 |
TMOD2,NECAB2,PRKCA |
| 1.025e-02 | -4.58 | positive regulation of release of cytochrome c from mitochondria | biological process | GO:0090200 | 29 | 3 | 17256 | 270 |
BNIP3,PMAIP1,BIK |
| 1.026e-02 | -4.58 | chr4q35 | MSigDB lists | chr4q35 | 28 | 3 | 17377 | 282 |
ACSL1,CCDC110,CYP4V2 |
| 1.026e-02 | -4.58 | GO_GLUCOSE_CATABOLIC_PROCESS | MSigDB lists | GO_GLUCOSE_CATABOLIC_PROCESS | 28 | 3 | 17377 | 282 |
GAPDH,ALDOA,HK2 |
| 1.026e-02 | -4.58 | REACTOME_CA_DEPENDENT_EVENTS | MSigDB lists | REACTOME_CA_DEPENDENT_EVENTS | 28 | 3 | 17377 | 282 |
PRKCA,PRKCD,ADCY1 |
| 1.029e-02 | -4.58 | human chr7q34 | chromosome location | human chr7q34 | 67 | 4 | 26185 | 331 |
KDM7A-DT,KDM7A,EPHB6,KIAA1549 |
| 1.030e-02 | -4.58 | enzyme linked receptor protein signaling pathway | biological process | GO:0007167 | 725 | 20 | 17256 | 270 |
BDNF,MSX1,PXN,RUNX2,ACVR1,DOCK1,UBASH3B,EFNA3,ATP6V1E2,GAREM1,GAS6,PLEKHA1,ACVR2B,PRKCA,GPLD1,FGR,GTF2F2,DAB2IP,MAPK13,EPHB6 |
| 1.031e-02 | -4.57 | KEGG_VASCULAR_SMOOTH_MUSCLE_CONTRACTION | MSigDB lists | KEGG_VASCULAR_SMOOTH_MUSCLE_CONTRACTION | 113 | 6 | 17377 | 282 |
ACTA2,ITPR2,PRKCA,ARHGEF11,PRKCD,ADCY1 |
| 1.033e-02 | -4.57 | negative regulation of transferase activity | biological process | GO:0051348 | 312 | 11 | 17256 | 270 |
TRIB3,PPM1E,DUSP8,PTPN6,UBASH3B,PRKCD,WWTR1,DAB2IP,CEBPA,SMYD3,PKIA |
| 1.033e-02 | -4.57 | BZIP | prosite domains | PS50217 | 51 | 4 | 12060 | 202 |
MAFB,CEBPA,DBP,DDIT3 |
| 1.036e-02 | -4.57 | response to inorganic substance | biological process | GO:0010035 | 489 | 15 | 17256 | 270 |
CPNE2,SLC40A1,SCN5A,UROS,SLC30A4,GNAO1,PRKCD,ADCY1,MAPK13,CEBPA,ABCC2,BNIP3,PLEKHA1,ABAT,GPLD1 |
| 1.037e-02 | -4.57 | Hippo signaling pathway -multiple species | KEGG pathways | hsa04392 | 29 | 3 | 7161 | 113 |
WWC1,SAV1,WWTR1 |
| 1.037e-02 | -4.57 | Hippo signaling pathway -multiple species | KEGG pathways | ko04392 | 29 | 3 | 7161 | 113 |
WWC1,SAV1,WWTR1 |
| 1.040e-02 | -4.57 | adenoid_cystic_carcinoma | COSMIC cancer mutations | adenoid_cystic_carcinoma | 1140 | 29 | 17385 | 281 |
IL17RD,CCDC148,RUNX2,ACVR1,ZNF395,PDK1,SPATA13,ACVR2B,PRKCA,PALLD,CBLN1,NEO1,ZNF827,FKBP9,TRIB3,FGR,LMLN,PLK2,MAP2K6,RPS6KL1,HK2,SGK1,MAPK13,MYOM2,KLHL31,TANC2,DNAH5,OR2W3,DDIT3 |
| 1.044e-02 | -4.56 | GO_PROTEIN_SERINE_THREONINE_KINASE_ACTIVITY | MSigDB lists | GO_PROTEIN_SERINE_THREONINE_KINASE_ACTIVITY | 428 | 14 | 17377 | 282 |
DYRK1B,ACVR1,MAP2K6,RPS6KL1,PLK2,PRKCD,ERN1,NUAK2,SGK1,STRADB,MAPK13,ACVR2B,PRKCA,SGK2 |
| 1.046e-02 | -4.56 | MODULE_378 | MSigDB lists | MODULE_378 | 385 | 13 | 17377 | 282 |
SPNS1,ACVR1,ACSL1,MAP2K6,PLEKHG1,WDR25,PRDM1,PDE4D,EPHB6,SAV1,CBLN1,PKIA,RERE |
| 1.047e-02 | -4.56 | scaffold protein binding | molecular function | GO:0097110 | 53 | 4 | 17224 | 278 |
NLGN4X,SCN5A,ITPR2,PDE4D |
| 1.049e-02 | -4.56 | GSE36078_UNTREATED_VS_AD5_T425A_HEXON_INF_MOUSE_LUNG_DC_UP | MSigDB lists | GSE36078_UNTREATED_VS_AD5_T425A_HEXON_INF_MOUSE_LUNG_DC_UP | 184 | 8 | 17377 | 282 |
C2orf88,PDK1,ADAMTS3,GNAO1,CYP4V2,KIF5C,PFN2,PGBD5 |
| 1.049e-02 | -4.56 | GSE36078_WT_VS_IL1R_KO_LUNG_DC_AFTER_AD5_T425A_HEXON_INF_DN | MSigDB lists | GSE36078_WT_VS_IL1R_KO_LUNG_DC_AFTER_AD5_T425A_HEXON_INF_DN | 184 | 8 | 17377 | 282 |
IL17RD,C2orf88,FKBP9,DLX2,ITPR2,ARHGEF11,EHD3,CYP4V2 |
| 1.049e-02 | -4.56 | GSE8921_UNSTIM_VS_TLR1_2_STIM_MONOCYTE_12H_UP | MSigDB lists | GSE8921_UNSTIM_VS_TLR1_2_STIM_MONOCYTE_12H_UP | 184 | 8 | 17377 | 282 |
LONRF1,QSOX1,FKBP9,HEBP1,LSM11,QPCTL,GAS6,TLR6 |
| 1.049e-02 | -4.56 | GSE12845_NAIVE_VS_DARKZONE_GC_TONSIL_BCELL_UP | MSigDB lists | GSE12845_NAIVE_VS_DARKZONE_GC_TONSIL_BCELL_UP | 184 | 8 | 17377 | 282 |
PDK1,PNRC1,LGR4,DACT1,HEBP1,HERC6,SATB1,JAM3 |
| 1.049e-02 | -4.56 | PEREZ_TP53_TARGETS | MSigDB lists | PEREZ_TP53_TARGETS | 1037 | 27 | 17377 | 282 |
MN1,C2orf88,BDNF,MSX1,MXI1,ACVR1,KLHL3,BVES,BACE1,BIK,ADCY1,MAFB,CEBPA,TNS1,WNT11,FAM198B,ABHD4,ABHD6,DACT1,GPR155,EMILIN2,TRIM3,MAPK13,DAB2IP,DISP1,MOXD1,KIAA1549 |
| 1.050e-02 | -4.56 | regulation of multicellular organismal process | biological process | GO:0051239 | 2993 | 62 | 17256 | 270 |
SCN5A,RUNX2,ACVR1,LGR4,ZHX3,DOCK1,BVES,CYP2J2,UBASH3B,PLXNA2,NDRG2,CHADL,CEBPA,ITPR2,GAS6,OVOL2,ABAT,ZNF219,PRKCA,CACNB4,PFN2,CBLN1,NCS1,IL17D,NUMBL,DACT1,MYC,PRKCD,EHD3,SGK1,PRICKLE2,INAVA,DAB2IP,PDE4D,GPR161,EPB41L5,ENAM,PHLDB2,LZTS3,BDNF,MSX1,GAPDH,PTPN6,EFNA3,NLGN4X,MAFB,WWC1,WNT11,PRDM1,ACVR2B,SAV1,TLR6,GPLD1,FGR,PLK2,GNAO1,WWTR1,HK2,MAPK13,DLX2,COBL,DDIT3 |
| 1.058e-02 | -4.55 | nervous system development | biological process | GO:0007399 | 2259 | 49 | 17256 | 270 |
ARHGAP26,SCN5A,RUNX2,ST14,PLXNA2,KIF5C,NDRG2,NRN1,OVOL2,GAS6,ABAT,PRKCA,HPCAL4,CBLN1,NCS1,NEO1,KDM7A,NUMBL,DLX6,DACT1,ZIC5,ZNF521,TRIM3,SGK1,BNIP3,DAB2IP,STXBP1,TSHR,BARX1,BDNF,LZTS3,MSX1,EFNA3,ADCY1,MAFB,NLGN4X,WNT11,SATB2,PRDM1,JAM3,RERE,TCF7L1,PLK2,GNAO1,CLMN,TMOD2,DLX2,APBA2,COBL |
| 1.062e-02 | -4.54 | animal organ morphogenesis | biological process | GO:0009887 | 875 | 23 | 17256 | 270 |
ENAM,SCN5A,SLC40A1,MSX1,ACVR1,RUNX2,LGR4,KLHL3,MAFB,SATB2,WNT11,PRDM1,ACVR2B,OVOL2,PLEKHA1,SAV1,DLX6,MYC,RBPMS2,WWTR1,ACTA2,MYOM2,DLX2 |
| 1.066e-02 | -4.54 | DELASERNA_MYOD_TARGETS_DN | MSigDB lists | DELASERNA_MYOD_TARGETS_DN | 53 | 4 | 17377 | 282 |
TCF7L1,ITPR2,EMILIN2,DDIT3 |
| 1.066e-02 | -4.54 | chr5q13 | MSigDB lists | chr5q13 | 53 | 4 | 17377 | 282 |
ANKRD31,SCAMP1,RASGRF2,MARVELD2 |
| 1.066e-02 | -4.54 | positive regulation of phosphorus metabolic process | biological process | GO:0010562 | 1129 | 28 | 17256 | 270 |
ACSL1,ACVR1,NECAB2,ADCY1,STRADB,WWC1,GAREM1,WNT11,GAS6,ACVR2B,TNFRSF10C,PRKCA,PFN2,TLR6,GPLD1,FGR,MAP2K6,PRKCD,ERN1,INAVA,TNFSF15,DAB2IP,EPHB6,TSHR,SMYD3,HSPA2,GPR161,PARP9 |
| 1.066e-02 | -4.54 | positive regulation of phosphate metabolic process | biological process | GO:0045937 | 1129 | 28 | 17256 | 270 |
ACSL1,ACVR1,NECAB2,ADCY1,STRADB,WWC1,GAREM1,WNT11,GAS6,ACVR2B,TNFRSF10C,PRKCA,PFN2,TLR6,GPLD1,FGR,MAP2K6,PRKCD,ERN1,INAVA,TNFSF15,DAB2IP,EPHB6,TSHR,SMYD3,HSPA2,GPR161,PARP9 |
| 1.067e-02 | -4.54 | Fc Epsilon Receptor I Signaling in Mast Cells | SMPDB pathways | SMP00358 | 32 | 3 | 992 | 15 |
PDK1,PRKCA,MAP2K6 |
| 1.067e-02 | -4.54 | Glycolysis | REACTOME pathways | R-HSA-70171 | 32 | 3 | 10287 | 148 |
GAPDH,ALDOA,HK2 |
| 1.069e-02 | -4.54 | FERM_N | pfam domains | PF09379 | 29 | 3 | 17054 | 271 |
EPB41L5,TLN2,PTPN21 |
| 1.069e-02 | -4.54 | cytoskeletal protein binding | molecular function | GO:0008092 | 897 | 24 | 17224 | 278 |
EPB41L5,SCN5A,PXN,GAPDH,KLHL3,DSTN,KIF5C,TNS1,PALLD,KIF21B,DYNC1I1,PFN2,FHOD3,MTUS1,IFT81,ALDOA,CLMN,MYOM2,TMOD2,MYH15,RAB27B,TLN2,HSPA2,COBL |
| 1.070e-02 | -4.54 | homotypic cell-cell adhesion | biological process | GO:0034109 | 55 | 4 | 17256 | 270 |
GAS6,STXBP1,PTPN6,UBASH3B |
| 1.070e-02 | -4.54 | nucleoside diphosphate phosphorylation | biological process | GO:0006165 | 55 | 4 | 17256 | 270 |
GAPDH,ALDOA,OGDHL,HK2 |
| 1.071e-02 | -4.54 | regulation of intracellular signal transduction | biological process | GO:1902531 | 1929 | 43 | 17256 | 270 |
ARHGAP26,NECAB2,DUSP8,RASAL2,ARHGEF11,NDRG2,GAS6,TNFRSF10C,PRKCA,MYORG,TIAM2,RALGPS2,PMAIP1,DACT1,MYC,PRKCD,RASD2,SRGAP1,INAVA,DAB2IP,PDE4D,EPHB6,PARP9,MSX1,PTPN6,SPATA13,WWC1,WNT11,GAREM1,PLEKHA1,TLR6,TRIB3,FGR,MAP2K6,WFS1,PLK2,RASGRF2,ERN1,PLEKHG1,ARHGAP28,TNFSF15,IQSEC2,DDIT3 |
| 1.073e-02 | -4.53 | positive regulation of ossification | biological process | GO:0045778 | 85 | 5 | 17256 | 270 |
CEBPA,RUNX2,ACVR2B,ACVR1,ZHX3 |
| 1.073e-02 | -4.53 | iron ion homeostasis | biological process | GO:0055072 | 85 | 5 | 17256 | 270 |
SLC40A1,SLC25A28,MYC,SFXN4,NEO1 |
| 1.073e-02 | -4.53 | IVANOVA_HEMATOPOIESIS_MATURE_CELL | MSigDB lists | IVANOVA_HEMATOPOIESIS_MATURE_CELL | 262 | 10 | 17377 | 282 |
SLC40A1,FGR,MXI1,ACSL1,HEBP1,MPP1,BNIP3L,STRADB,ACTA2,TLR6 |
| 1.074e-02 | -4.53 | GO_NEPHRON_DEVELOPMENT | MSigDB lists | GO_NEPHRON_DEVELOPMENT | 114 | 6 | 17377 | 282 |
ACTA2,WNT11,LGR4,KLHL3,MYC,WWTR1 |
| 1.074e-02 | -4.53 | CHEBOTAEV_GR_TARGETS_DN | MSigDB lists | CHEBOTAEV_GR_TARGETS_DN | 114 | 6 | 17377 | 282 |
PHLDB2,PALLD,CACNB4,PFN2,SOX21,PKIA |
| 1.074e-02 | -4.53 | GO_KIDNEY_MORPHOGENESIS | MSigDB lists | GO_KIDNEY_MORPHOGENESIS | 82 | 5 | 17377 | 282 |
WNT11,LGR4,KLHL3,MYC,WWTR1 |
| 1.074e-02 | -4.53 | STEIN_ESR1_TARGETS | MSigDB lists | STEIN_ESR1_TARGETS | 82 | 5 | 17377 | 282 |
SGK1,ABAT,PNRC1,RAB27B,SLC39A8 |
| 1.074e-02 | -4.53 | BURTON_ADIPOGENESIS_8 | MSigDB lists | BURTON_ADIPOGENESIS_8 | 82 | 5 | 17377 | 282 |
ACTA2,B9D1,BDNF,PHLDB2,DSTN |
| 1.074e-02 | -4.53 | GO_POSITIVE_REGULATION_OF_OSSIFICATION | MSigDB lists | GO_POSITIVE_REGULATION_OF_OSSIFICATION | 82 | 5 | 17377 | 282 |
CEBPA,ACVR2B,ACVR1,RUNX2,ZHX3 |
| 1.076e-02 | -4.53 | GO_NEGATIVE_REGULATION_OF_PHOSPHATE_METABOLIC_PROCESS | MSigDB lists | GO_NEGATIVE_REGULATION_OF_PHOSPHATE_METABOLIC_PROCESS | 518 | 16 | 17377 | 282 |
DUSP8,UBASH3B,PTPN6,NDRG2,CEBPA,PRKCA,PPM1E,TRIB3,MYC,DACT1,WWTR1,PRKCD,DAB2IP,PDE4D,SMYD3,PKIA |
| 1.076e-02 | -4.53 | GO_NEGATIVE_REGULATION_OF_PHOSPHORUS_METABOLIC_PROCESS | MSigDB lists | GO_NEGATIVE_REGULATION_OF_PHOSPHORUS_METABOLIC_PROCESS | 518 | 16 | 17377 | 282 |
DUSP8,UBASH3B,PTPN6,NDRG2,CEBPA,PRKCA,PPM1E,TRIB3,MYC,DACT1,PRKCD,WWTR1,DAB2IP,PDE4D,SMYD3,PKIA |
| 1.076e-02 | -4.53 | HDAC1 (histone deacetylase 1) | protein interactions | 3065 | 550 | 17 | 17029 | 283 |
ZNF827,ZNF516,RUNX2,ZNF395,DACT1,UBASH3B,MYC,ZNF521,BNIP3,SATB2,CEBPA,PRDM1,ZNF219,RNF157,SATB1,DDIT3,RERE |
| 1.081e-02 | -4.53 | GSE37534_UNTREATED_VS_ROSIGLITAZONE_TREATED_CD4_TCELL_PPARG1_AND_FOXP3_TRASDUCED_UP | MSigDB lists | GSE37534_UNTREATED_VS_ROSIGLITAZONE_TREATED_CD4_TCELL_PPARG1_AND_FOXP3_TRASDUCED_UP | 185 | 8 | 17377 | 282 |
MN1,TMEM53,ARHGEF11,ACVR2B,LHPP,ZNF219,EXOG,NIPSNAP3B |
| 1.081e-02 | -4.53 | GSE21063_CTRL_VS_ANTI_IGM_STIM_BCELL_NFATC1_KO_16H_UP | MSigDB lists | GSE21063_CTRL_VS_ANTI_IGM_STIM_BCELL_NFATC1_KO_16H_UP | 185 | 8 | 17377 | 282 |
RGS17,PLK2,EHD3,ATOX1,TNS1,NRN1,VGLL4,PARP9 |
| 1.082e-02 | -4.53 | S_TKc | smart domains | SM00220 | 349 | 13 | 9493 | 172 |
DYRK1B,TRIB3,ACVR1,MAP2K6,PLK2,PRKCD,ERN1,NUAK2,SGK1,MAPK13,SGK2,PRKCA,GRK3 |
| 1.082e-02 | -4.53 | FAM19A4 (family with sequence similarity 19 member A4, C-C motif chemokine like) | protein interactions | 151647 | 52 | 4 | 17029 | 283 |
ITPR2,MOXD1,GPLD1,PLXNA2 |
| 1.082e-02 | -4.53 | V$SMAD3_Q6 | MSigDB lists | V$SMAD3_Q6 | 223 | 9 | 17377 | 282 |
MN1,KCTD15,ACVR1,PTPN6,RASL11B,ATP6V1E2,PDE4D,SAV1,HMCN1 |
| 1.084e-02 | -4.52 | GO_SCHMIDT_LANTERMAN_INCISURE | MSigDB lists | GO_SCHMIDT_LANTERMAN_INCISURE | 10 | 2 | 17377 | 282 |
JAM3,MARVELD2 |
| 1.084e-02 | -4.52 | PID_P38_GAMMA_DELTA_PATHWAY | MSigDB lists | PID_P38_GAMMA_DELTA_PATHWAY | 10 | 2 | 17377 | 282 |
MAPK13,MAP2K6 |
| 1.084e-02 | -4.52 | DELACROIX_RAR_BOUND_ES | MSigDB lists | DELACROIX_RAR_BOUND_ES | 430 | 14 | 17377 | 282 |
TMEM63C,PDK1,PTPN6,ZIC5,EBF4,SLX1B,CEBPA,FAM198B,ZNF219,COBL,DDIT3,PLEKHB1,PHC1,C3orf67 |
| 1.086e-02 | -4.52 | growth cone | cellular component | GO:0030426 | 157 | 7 | 18223 | 280 |
KIF5C,NDRG2,TMOD2,KIF21B,PALLD,COBL,TIAM2 |
| 1.086e-02 | -4.52 | bZIP | interpro domains | IPR004827 | 54 | 4 | 18492 | 296 |
MAFB,CEBPA,DBP,DDIT3 |
| 1.091e-02 | -4.52 | FERM_N | interpro domains | IPR018979 | 29 | 3 | 18492 | 296 |
EPB41L5,TLN2,PTPN21 |
| 1.094e-02 | -4.52 | LRRIQ1 (leucine rich repeats and IQ motif containing 1) | protein interactions | 84125 | 28 | 3 | 17029 | 283 |
ACVR2B,ACVR1,LGR4 |
| 1.094e-02 | -4.52 | Wdr5 (WD repeat domain 5) | protein interactions | 140858 | 28 | 3 | 17029 | 283 |
EPB41L5,KIAA0355,RERE |
| 1.096e-02 | -4.51 | GSE2770_TGFB_AND_IL4_VS_TGFB_AND_IL12_TREATED_ACT_CD4_TCELL_2H_UP | MSigDB lists | GSE2770_TGFB_AND_IL4_VS_TGFB_AND_IL12_TREATED_ACT_CD4_TCELL_2H_UP | 149 | 7 | 17377 | 282 |
QSOX1,FKBP9,APBA2,KIAA0355,MAP2K6,FHOD3,RERE |
| 1.097e-02 | -4.51 | EP300 (E1A binding protein p300) | protein interactions | 2033 | 507 | 16 | 17029 | 283 |
MN1,GAPDH,RUNX2,CEBPA,SAV1,PRKCA,DYNC1I1,SATB1,RERE,DYRK1B,MYC,PRKCD,ACTA2,DBP,COBL,DDIT3 |
| 1.104e-02 | -4.51 | regionalization | biological process | GO:0003002 | 315 | 11 | 17256 | 270 |
EPB41L5,MSX1,PLXNA2,MAFB,DISP1,OVOL2,DLX2,ACVR2B,COBL,BARX1,DDIT3 |
| 1.109e-02 | -4.50 | Insulin Signaling | WikiPathways | WP481 | 161 | 8 | 5312 | 101 |
SGK1,TRIB3,MAPK13,SGK2,PRKCA,STXBP1,MAP2K6,PRKCD |
| 1.112e-02 | -4.50 | PASINI_SUZ12_TARGETS_DN | MSigDB lists | PASINI_SUZ12_TARGETS_DN | 304 | 11 | 17377 | 282 |
BDNF,PHLDB2,PLK2,MARVELD2,MYC,WWTR1,KIF5C,ACTA2,PALLD,NCS1,PKIA |
| 1.113e-02 | -4.50 | organophosphate catabolic process | biological process | GO:0046434 | 155 | 7 | 17256 | 270 |
PDE4D,GAPDH,ABHD6,SMPDL3A,ALDOA,OGDHL,HK2 |
| 1.115e-02 | -4.50 | GSE3039_NKT_CELL_VS_ALPHAALPHA_CD8_TCELL_UP | MSigDB lists | GSE3039_NKT_CELL_VS_ALPHAALPHA_CD8_TCELL_UP | 186 | 8 | 17377 | 282 |
TMEM53,QSOX1,MAPK13,SCAMP1,ARRDC4,HEBP1,EMILIN2,MTUS1 |
| 1.115e-02 | -4.50 | GSE25123_WT_VS_PPARG_KO_MACROPHAGE_ROSIGLITAZONE_STIM_UP | MSigDB lists | GSE25123_WT_VS_PPARG_KO_MACROPHAGE_ROSIGLITAZONE_STIM_UP | 186 | 8 | 17377 | 282 |
GPR155,RHPN2,MAP7,PLEKHA1,DISP1,GAS6,VGLL4,MTUS1 |
| 1.115e-02 | -4.50 | GSE10325_BCELL_VS_MYELOID_DN | MSigDB lists | GSE10325_BCELL_VS_MYELOID_DN | 186 | 8 | 17377 | 282 |
MPP1,BLVRB,PRKCD,MAFB,KIAA0513,CEBPA,TNFRSF10C,TBC1D8 |
| 1.115e-02 | -4.50 | GSE39820_TGFBETA1_VS_TGFBETA3_IN_IL6_IL23A_TREATED_CD4_TCELL_DN | MSigDB lists | GSE39820_TGFBETA1_VS_TGFBETA3_IN_IL6_IL23A_TREATED_CD4_TCELL_DN | 186 | 8 | 17377 | 282 |
LMLN,GNAO1,LRRIQ3,PJA1,ZNF219,RADIL,ZNF558,MTUS1 |
| 1.115e-02 | -4.50 | GSE21774_CD62L_POS_CD56_BRIGHT_VS_CD62L_NEG_CD56_DIM_NK_CELL_UP | MSigDB lists | GSE21774_CD62L_POS_CD56_BRIGHT_VS_CD62L_NEG_CD56_DIM_NK_CELL_UP | 186 | 8 | 17377 | 282 |
PRSS16,KMO,BACE1,SRGAP1,CEBPA,SHISA2,SATB1,MTUS1 |
| 1.115e-02 | -4.50 | GSE1460_INTRATHYMIC_T_PROGENITOR_VS_CD4_THYMOCYTE_DN | MSigDB lists | GSE1460_INTRATHYMIC_T_PROGENITOR_VS_CD4_THYMOCYTE_DN | 186 | 8 | 17377 | 282 |
ZNF516,SGK1,MAPK13,SATB2,BNIP3,PLEKHA1,ABAT,SATB1 |
| 1.115e-02 | -4.50 | RAF_UP.V1_UP | MSigDB lists | RAF_UP.V1_UP | 186 | 8 | 17377 | 282 |
CLMN,ARHGAP26,RASL11B,ACSL1,PDE4D,ABHD6,HSPA2,TBC1D8 |
| 1.115e-02 | -4.50 | GSE10325_CD4_TCELL_VS_BCELL_UP | MSigDB lists | GSE10325_CD4_TCELL_VS_BCELL_UP | 186 | 8 | 17377 | 282 |
ACVR1,PXN,SLC39A8,BNIP3,PDE4D,PRKCA,STXBP1,APBA2 |
| 1.117e-02 | -4.49 | positive regulation of multicellular organismal process | biological process | GO:0051240 | 1608 | 37 | 17256 | 270 |
RUNX2,ACVR1,LGR4,ZHX3,DOCK1,PLXNA2,CEBPA,GAS6,ABAT,OVOL2,ZNF219,PRKCA,CBLN1,IL17D,NUMBL,MYC,INAVA,DAB2IP,PDE4D,EPB41L5,BDNF,PHLDB2,ENAM,GAPDH,WNT11,PRDM1,ACVR2B,TLR6,GPLD1,FGR,PLK2,WWTR1,HK2,MAPK13,DLX2,COBL,DDIT3 |
| 1.125e-02 | -4.49 | positive regulation of protein binding | biological process | GO:0032092 | 86 | 5 | 17256 | 270 |
EPB41L5,TRIB3,BDNF,DACT1,PLK2 |
| 1.126e-02 | -4.49 | regulation of amino acid transport | biological process | GO:0051955 | 30 | 3 | 17256 | 270 |
ABAT,KMO,STXBP1 |
| 1.126e-02 | -4.49 | regulation of nuclease activity | biological process | GO:0032069 | 30 | 3 | 17256 | 270 |
DAB2IP,PRKCD,ERN1 |
| 1.126e-02 | -4.49 | epithelial cell morphogenesis | biological process | GO:0003382 | 30 | 3 | 17256 | 270 |
EPB41L5,PALLD,ST14 |
| 1.126e-02 | -4.49 | response to arsenic-containing substance | biological process | GO:0046685 | 30 | 3 | 17256 | 270 |
MAPK13,ABCC2,UROS |
| 1.131e-02 | -4.48 | GO_NEURON_DIFFERENTIATION | MSigDB lists | GO_NEURON_DIFFERENTIATION | 848 | 23 | 17377 | 282 |
BDNF,RUNX2,ADCY1,PLXNA2,EFNA3,KIF5C,NLGN4X,SATB2,WNT11,PRDM1,CBLN1,JAM3,NEO1,RERE,NUMBL,GNAO1,ZNF521,CLMN,SGK1,DAB2IP,DLX2,STXBP1,COBL |
| 1.131e-02 | -4.48 | RORIE_TARGETS_OF_EWSR1_FLI1_FUSION_UP | MSigDB lists | RORIE_TARGETS_OF_EWSR1_FLI1_FUSION_UP | 29 | 3 | 17377 | 282 |
MN1,DLX2,MYC |
| 1.131e-02 | -4.48 | GO_BROWN_FAT_CELL_DIFFERENTIATION | MSigDB lists | GO_BROWN_FAT_CELL_DIFFERENTIATION | 29 | 3 | 17377 | 282 |
BNIP3,CEBPA,ZNF516 |
| 1.131e-02 | -4.48 | PARK_TRETINOIN_RESPONSE_AND_PML_RARA_FUSION | MSigDB lists | PARK_TRETINOIN_RESPONSE_AND_PML_RARA_FUSION | 29 | 3 | 17377 | 282 |
CEBPA,FGR,BIK |
| 1.131e-02 | -4.48 | MODULE_184 | MSigDB lists | MODULE_184 | 29 | 3 | 17377 | 282 |
ABAT,ACSL1,BLVRB |
| 1.134e-02 | -4.48 | GSE19198_1H_VS_6H_IL21_TREATED_TCELL_UP | MSigDB lists | GSE19198_1H_VS_6H_IL21_TREATED_TCELL_UP | 150 | 7 | 17377 | 282 |
SGK1,ARHGAP26,SHISA2,WNT11,FAM78B,BIK,EEPD1 |
| 1.134e-02 | -4.48 | GO_AMEBOIDAL_TYPE_CELL_MIGRATION | MSigDB lists | GO_AMEBOIDAL_TYPE_CELL_MIGRATION | 150 | 7 | 17377 | 282 |
EPB41L5,TNS1,WNT11,OVOL2,ACVR1,CENPV,GPLD1 |
| 1.134e-02 | -4.48 | AKAP6 (A-kinase anchoring protein 6) | protein interactions | 9472 | 10 | 2 | 17029 | 283 |
PDE4D,MYC |
| 1.134e-02 | -4.48 | WNK2 (WNK lysine deficient protein kinase 2) | protein interactions | 65268 | 10 | 2 | 17029 | 283 |
SGK1,KLHL3 |
| 1.134e-02 | -4.48 | IFNA4 (interferon alpha 4) | protein interactions | 3441 | 10 | 2 | 17029 | 283 |
RECK,ALDOA |
| 1.139e-02 | -4.48 | positive regulation of actin filament bundle assembly | biological process | GO:0032233 | 56 | 4 | 17256 | 270 |
WNT11,PPM1E,PXN,PFN2 |
| 1.139e-02 | -4.48 | lateral plasma membrane | cellular component | GO:0016328 | 57 | 4 | 18223 | 280 |
ARL2,EPCAM,SCN5A,BVES |
| 1.146e-02 | -4.47 | YNGTTNNNATT_UNKNOWN | MSigDB lists | YNGTTNNNATT_UNKNOWN | 347 | 12 | 17377 | 282 |
BDNF,IFT81,MXI1,KCTD15,ACVR1,GNAO1,ZNF521,CLMN,PRDM1,SATB1,VGLL4,CBLN1 |
| 1.149e-02 | -4.47 | GSE21380_NON_TFH_VS_TFH_CD4_TCELL_UP | MSigDB lists | GSE21380_NON_TFH_VS_TFH_CD4_TCELL_UP | 187 | 8 | 17377 | 282 |
PNRC1,DOCK1,RECK,UBASH3B,WFS1,SPATA13,CCDC122,RERE |
| 1.149e-02 | -4.47 | GSE37301_LYMPHOID_PRIMED_MPP_VS_GRAN_MONO_PROGENITOR_UP | MSigDB lists | GSE37301_LYMPHOID_PRIMED_MPP_VS_GRAN_MONO_PROGENITOR_UP | 187 | 8 | 17377 | 282 |
PMAIP1,MPP1,MYC,HK2,GTF2F2,SLC25A28,TNFRSF17,SATB1 |
| 1.149e-02 | -4.47 | GSE25085_FETAL_LIVER_VS_FETAL_BM_SP4_THYMIC_IMPLANT_DN | MSigDB lists | GSE25085_FETAL_LIVER_VS_FETAL_BM_SP4_THYMIC_IMPLANT_DN | 187 | 8 | 17377 | 282 |
CCDC126,FGR,SCAMP1,PLEKHG1,MAFB,P4HA1,TMEM37,TANC2 |
| 1.149e-02 | -4.47 | GSE20366_TREG_VS_NAIVE_CD4_TCELL_UP | MSigDB lists | GSE20366_TREG_VS_NAIVE_CD4_TCELL_UP | 187 | 8 | 17377 | 282 |
SCAMP1,MPP1,UBASH3B,MYC,NDRG2,P4HA1,TANC2,PHC1 |
| 1.149e-02 | -4.47 | GSE36888_UNTREATED_VS_IL2_TREATED_TCELL_17H_UP | MSigDB lists | GSE36888_UNTREATED_VS_IL2_TREATED_TCELL_17H_UP | 187 | 8 | 17377 | 282 |
CEBPA,TNS1,DBP,RASAL2,PALLD,MPP1,BACE1,BLVRB |
| 1.149e-02 | -4.47 | GSE11961_MEMORY_BCELL_DAY7_VS_PLASMA_CELL_DAY7_UP | MSigDB lists | GSE11961_MEMORY_BCELL_DAY7_VS_PLASMA_CELL_DAY7_UP | 187 | 8 | 17377 | 282 |
ACSL1,ST14,MARVELD2,WFS1,PRKCD,CAPN5,DBP,STXBP1 |
| 1.149e-02 | -4.47 | GSE11961_MARGINAL_ZONE_BCELL_VS_GERMINAL_CENTER_BCELL_DAY40_DN | MSigDB lists | GSE11961_MARGINAL_ZONE_BCELL_VS_GERMINAL_CENTER_BCELL_DAY40_DN | 187 | 8 | 17377 | 282 |
SPATA9,ACSL1,SLC30A4,RALGPS2,ARRDC4,RADIL,PRKCD,NUAK2 |
| 1.149e-02 | -4.47 | GSE36078_WT_VS_IL1R_KO_LUNG_DC_AFTER_AD5_INF_DN | MSigDB lists | GSE36078_WT_VS_IL1R_KO_LUNG_DC_AFTER_AD5_INF_DN | 187 | 8 | 17377 | 282 |
EPB41L5,CCDC126,TRIB3,PDK1,MPP1,UBASH3B,WFS1,SMPDL3A |
| 1.149e-02 | -4.47 | GSE22886_TH1_VS_TH2_48H_ACT_UP | MSigDB lists | GSE22886_TH1_VS_TH2_48H_ACT_UP | 187 | 8 | 17377 | 282 |
TMEM53,ST14,BACE1,SGK1,KIF21B,STXBP1,BARX1,DDIT3 |
| 1.149e-02 | -4.47 | GSE21670_TGFB_VS_TGFB_AND_IL6_TREATED_CD4_TCELL_UP | MSigDB lists | GSE21670_TGFB_VS_TGFB_AND_IL6_TREATED_CD4_TCELL_UP | 187 | 8 | 17377 | 282 |
RECK,UBASH3B,GPR155,DBP,PRKCA,COLEC10,PFN2,VGLL4 |
| 1.149e-02 | -4.47 | GSE13306_TREG_VS_TCONV_SPLEEN_UP | MSigDB lists | GSE13306_TREG_VS_TCONV_SPLEEN_UP | 187 | 8 | 17377 | 282 |
SGK1,ENAM,MSX1,UROS,DOCK1,DYNC1I1,MPP1,ZDHHC23 |
| 1.154e-02 | -4.46 | tibia | COSMIC cancer mutations | tibia | 853 | 23 | 17385 | 281 |
EPB41L5,SCN5A,TMEM63C,ACSL1,RASAL2,ZHX3,DOCK1,PLXNA2,NDRG2,TNS1,SAV1,PALLD,MTUS1,FGR,RPS6KL1,MAP2K6,LRRIQ3,WWTR1,PLEKHG1,TRIM3,TNFSF15,GPR161,PARP9 |
| 1.155e-02 | -4.46 | MODULE_317 | MSigDB lists | MODULE_317 | 390 | 13 | 17377 | 282 |
SPNS1,ACVR1,ACSL1,MAP2K6,PLEKHG1,WDR25,PRDM1,EPHB6,PDE4D,SAV1,CBLN1,PKIA,RERE |
| 1.156e-02 | -4.46 | KEGG_MAPK_SIGNALING_PATHWAY | MSigDB lists | KEGG_MAPK_SIGNALING_PATHWAY | 265 | 10 | 17377 | 282 |
BDNF,DUSP8,MAP2K6,RASGRF2,MYC,MAPK13,PRKCA,CACNB4,HSPA2,DDIT3 |
| 1.157e-02 | -4.46 | regulation of biological process | biological process | GO:0050789 | 11524 | 198 | 17256 | 270 |
ARHGAP26,ACSL1,ACVR1,DUSP8,LGR4,RECK,HEBP1,LSM11,NDRG2,CEBPA,ITPR2,ABAT,PRKCA,CACNB4,ABHD6,NCS1,EPCAM,PPM1E,PMAIP1,DLX6,CFHR1,TMEM37,EPHB6,OR2W3,TSHR,FANK1,ZNF391,TBC1D8,PNRC1,WISP3,DSTN,CAPN5,BNIP3L,ACVR2B,PLEKHA1,SGK2,SAV1,GRK3,PLEKHB1,SPNS1,DYRK1B,TCF7L1,PLK2,RASGRF2,ERN1,ALDOA,ARHGAP28,MAPK13,TMOD2,DLX2,APBA2,LONRF1,GPR63,SCN5A,RGS16,RUNX2,ZNF395,ZHX3,BVES,CYP2J2,FBXO4,UBASH3B,ATP6V1E2,SETBP1,RASL11B,CHADL,TNFRSF10C,SATB1,PFN2,HPCAL4,MYORG,FHOD3,MTUS1,IL17D,NUMBL,SLC30A4,RALGPS2,MYC,ZIC5,SRGAP1,EBF4,INAVA,BNIP3,NCEH1,VGLL4,STXBP1,BARX1,GPR161,EPB41L5,ENAM,BDNF,QSOX1,IL17RD,EFNA3,SPATA13,WWC1,MAFB,STRADB,SHISA2,PRDM1,OR11H4,ARRDC4,ZNF558,ADAMTS3,HK2,CLMN,IQSEC2,SMYD3,ZNF516,RASAL2,DOCK1,C4A,PLXNA2,RHPN2,COLEC10,RADIL,CBLN1,TIAM2,ZNF827,KMO,DACT1,RPS6KL1,ZNF521,DAB2IP,PDE4D,RAB27B,KIAA1549,HSPA2,PHLDB2,GAPDH,PDK1,SOX21,PTPN6,ADCY1,NLGN4X,WNT11,SATB2,PXYLP1,RAB38,TBC1D16,JAM3,CENPV,ZNF697,RBPMS2,WFS1,WWTR1,PLEKHG1,TNFSF15,DISP1,DBP,KLHL31,COBL,KCTD1,NECAB2,MXI1,ARHGEF11,BACE1,BIK,ARL2,SLX1B,GAS6,OVOL2,ZNF219,NEO1,KDM7A,RGS17,GPR155,PRKCD,EHD3,RASD2,GTF2F2,ACTA2,SGK1,PRICKLE2,PARP9,B9D1,MN1,SLC40A1,LZTS3,PXN,MSX1,MPP1,NUAK2,GAREM1,TLR6,RERE,GPLD1,CTIF,TRIB3,FGR,GNAO1,MAP2K6,THAP10,TNFRSF17,B4GALT7,DDIT3,PKIA,PHC1 |
| 1.163e-02 | -4.45 | LIU_VMYB_TARGETS_UP | MSigDB lists | LIU_VMYB_TARGETS_UP | 116 | 6 | 17377 | 282 |
ARHGAP26,PPM1E,SATB2,OVOL2,HSPA2,BNIP3L |
| 1.163e-02 | -4.45 | MORF_ATF2 | MSigDB lists | MORF_ATF2 | 306 | 11 | 17377 | 282 |
PPM1E,RUNX2,ADAMTS3,WISP3,KLHL23,MAP2K6,PDE4D,PRKCA,TANC2,SMYD3,PLEKHB1 |
| 1.173e-02 | -4.45 | GSE32034_UNTREATED_VS_ROSIGLIZATONE_TREATED_LY6C_LOW_MONOCYTE_UP | MSigDB lists | GSE32034_UNTREATED_VS_ROSIGLIZATONE_TREATED_LY6C_LOW_MONOCYTE_UP | 151 | 7 | 17377 | 282 |
KIAA0513,WDR25,EPB41L5,TNFRSF17,GPLD1,NEO1,RERE |
| 1.174e-02 | -4.45 | DOANE_RESPONSE_TO_ANDROGEN_DN | MSigDB lists | DOANE_RESPONSE_TO_ANDROGEN_DN | 226 | 9 | 17377 | 282 |
KIF5C,MN1,FAM198B,HERC6,PALLD,KMO,MPP1,PRKCD,PHC1 |
| 1.174e-02 | -4.44 | striated muscle thin filament | cellular component | GO:0005865 | 31 | 3 | 18223 | 280 |
MYOM2,TMOD2,FHOD3 |
| 1.181e-02 | -4.44 | zymogen granule membrane | cellular component | GO:0042589 | 11 | 2 | 18223 | 280 |
RAB27B,SCAMP1 |
| 1.183e-02 | -4.44 | GSE20715_0H_VS_24H_OZONE_LUNG_UP | MSigDB lists | GSE20715_0H_VS_24H_OZONE_LUNG_UP | 188 | 8 | 17377 | 282 |
EPB41L5,SLC40A1,MPP1,RASGRF2,RHPN2,FAM198B,PRDM1,SATB1 |
| 1.183e-02 | -4.44 | GSE21546_SAP1A_KO_VS_SAP1A_KO_AND_ELK1_KO_DP_THYMOCYTES_UP | MSigDB lists | GSE21546_SAP1A_KO_VS_SAP1A_KO_AND_ELK1_KO_DP_THYMOCYTES_UP | 188 | 8 | 17377 | 282 |
FKBP9,CPNE2,ABCC2,ACVR1,PRSS16,ABHD4,ADAMTS3,CYP4V2 |
| 1.183e-02 | -4.44 | GSE2770_IL12_VS_TGFB_AND_IL12_TREATED_ACT_CD4_TCELL_48H_DN | MSigDB lists | GSE2770_IL12_VS_TGFB_AND_IL12_TREATED_ACT_CD4_TCELL_48H_DN | 188 | 8 | 17377 | 282 |
EPB41L5,ZNF395,KLHL23,CCDC110,EMILIN2,EEPD1,COBL,FHOD3 |
| 1.183e-02 | -4.44 | GSE36476_YOUNG_VS_OLD_DONOR_MEMORY_CD4_TCELL_40H_TSST_ACT_DN | MSigDB lists | GSE36476_YOUNG_VS_OLD_DONOR_MEMORY_CD4_TCELL_40H_TSST_ACT_DN | 188 | 8 | 17377 | 282 |
ACVR1,KIAA0355,PRKCD,KIAA0408,PLEKHA1,PRKCA,PLEKHB1,TBC1D8 |
| 1.183e-02 | -4.44 | GSE9650_NAIVE_VS_EXHAUSTED_CD8_TCELL_DN | MSigDB lists | GSE9650_NAIVE_VS_EXHAUSTED_CD8_TCELL_DN | 188 | 8 | 17377 | 282 |
EPCAM,PHLDB2,RGS16,ACSL1,DUSP8,RASGRF2,EPHB6,PRDM1 |
| 1.183e-02 | -4.44 | GSE40666_NAIVE_VS_EFFECTOR_CD8_TCELL_DN | MSigDB lists | GSE40666_NAIVE_VS_EFFECTOR_CD8_TCELL_DN | 188 | 8 | 17377 | 282 |
CCDC126,ARHGAP26,LHPP,NCEH1,ABHD4,TBC1D16,MYC,C3orf67 |
| 1.183e-02 | -4.44 | GSE46606_IRF4_KO_VS_WT_UNSTIM_BCELL_UP | MSigDB lists | GSE46606_IRF4_KO_VS_WT_UNSTIM_BCELL_UP | 188 | 8 | 17377 | 282 |
GPR155,PLXNA2,MAFB,SGK1,KIF5C,FAM198B,ACVR2B,MTUS1 |
| 1.183e-02 | -4.44 | GSE8685_IL2_STARVED_VS_IL21_ACT_IL2_STARVED_CD4_TCELL_UP | MSigDB lists | GSE8685_IL2_STARVED_VS_IL21_ACT_IL2_STARVED_CD4_TCELL_UP | 188 | 8 | 17377 | 282 |
PPM1E,CPNE2,SLC40A1,LHPP,RALGPS2,UROS,SOX21,RERE |
| 1.184e-02 | -4.44 | connective tissue development | biological process | GO:0061448 | 195 | 8 | 17256 | 270 |
DYRK1B,MSX1,ZNF516,RUNX2,ACTA2,SATB2,DLX2,GPLD1 |
| 1.187e-02 | -4.43 | Thromboxane A2 receptor signaling | Pathway Interaction DB | txa2pathway | 45 | 4 | 2226 | 45 |
FGR,PRKCA,GRK3,PRKCD |
| 1.189e-02 | -4.43 | - | gene3d domains | 3.40.50.1820 | 107 | 6 | 8148 | 145 |
NLGN4X,NDRG2,TMEM53,PRSS16,ABHD4,ABHD6 |
| 1.190e-02 | -4.43 | GO_REGIONALIZATION | MSigDB lists | GO_REGIONALIZATION | 307 | 11 | 17377 | 282 |
EPB41L5,MSX1,PLXNA2,MAFB,DISP1,OVOL2,DLX2,ACVR2B,BARX1,COBL,DDIT3 |
| 1.191e-02 | -4.43 | positive regulation of protein modification process | biological process | GO:0031401 | 1191 | 29 | 17256 | 270 |
ACSL1,ACVR1,NECAB2,FBXO4,ADCY1,STRADB,WWC1,GAREM1,WNT11,GAS6,ACVR2B,TNFRSF10C,PRKCA,ARRDC4,PFN2,TLR6,TRIB3,MAP2K6,WFS1,PRKCD,ERN1,RASD2,INAVA,TNFSF15,DAB2IP,EPHB6,SMYD3,HSPA2,PARP9 |
| 1.195e-02 | -4.43 | nephron development | biological process | GO:0072006 | 121 | 6 | 17256 | 270 |
ACTA2,WNT11,LGR4,KLHL3,MYC,WWTR1 |
| 1.197e-02 | -4.43 | inorganic cation transmembrane transport | biological process | GO:0098662 | 544 | 16 | 17256 | 270 |
SLC40A1,SCN5A,SLC30A4,SLC9C1,SLC39A8,ATOX1,ATP6V1E2,SLC25A28,ITPR2,GAS6,TMEM37,SLC2A13,CACNB4,ATP6AP1L,NCS1,DDIT3 |
| 1.197e-02 | -4.43 | Vascular smooth muscle contraction | KEGG pathways | ko04270 | 121 | 6 | 7161 | 113 |
ACTA2,ITPR2,PRKCA,ARHGEF11,PRKCD,ADCY1 |
| 1.197e-02 | -4.43 | Vascular smooth muscle contraction | KEGG pathways | hsa04270 | 121 | 6 | 7161 | 113 |
ACTA2,ITPR2,PRKCA,ARHGEF11,PRKCD,ADCY1 |
| 1.198e-02 | -4.42 | HTH_motif | interpro domains | IPR000047 | 30 | 3 | 18492 | 296 |
DLX2,BARX1,DLX6 |
| 1.210e-02 | -4.41 | bone-humerus-other-chondroblastoma | COSMIC cancer mutations | bone-humerus-other-chondroblastoma | 309 | 11 | 17385 | 281 |
ARHGAP26,FKBP9,ZNF521,RHPN2,RAB38,TLN2,TSHR,HMCN1,COBL,FHOD3,CTIF |
| 1.213e-02 | -4.41 | GSE13485_CTRL_VS_DAY3_YF17D_VACCINE_PBMC_UP | MSigDB lists | GSE13485_CTRL_VS_DAY3_YF17D_VACCINE_PBMC_UP | 152 | 7 | 17377 | 282 |
RGS16,NRN1,WNT11,MXI1,SLC30A4,PNRC1,HSPA2 |
| 1.214e-02 | -4.41 | STK33_NOMO_UP | MSigDB lists | STK33_NOMO_UP | 267 | 10 | 17377 | 282 |
ACVR1,KMO,GAN,SGK1,SETBP1,TNFSF15,FAM198B,NCEH1,TLR6,PGBD5 |
| 1.219e-02 | -4.41 | GSE17721_LPS_VS_POLYIC_6H_BMDC_DN | MSigDB lists | GSE17721_LPS_VS_POLYIC_6H_BMDC_DN | 189 | 8 | 17377 | 282 |
FGR,PNRC1,MYC,ALDOA,BNIP3L,EEPD1,SGK1,TMEM37 |
| 1.219e-02 | -4.41 | GSE7460_CTRL_VS_TGFB_TREATED_ACT_FOXP3_HET_TCONV_DN | MSigDB lists | GSE7460_CTRL_VS_TGFB_TREATED_ACT_FOXP3_HET_TCONV_DN | 189 | 8 | 17377 | 282 |
IL17RD,ZNF827,UBASH3B,SGK1,DBP,PRKCA,ABHD6,TBC1D16 |
| 1.219e-02 | -4.41 | GSE29618_BCELL_VS_MONOCYTE_DN | MSigDB lists | GSE29618_BCELL_VS_MONOCYTE_DN | 189 | 8 | 17377 | 282 |
QSOX1,ACSL1,PXN,MPP1,BLVRB,MAFB,KIAA0513,CEBPA |
| 1.219e-02 | -4.41 | GSE24210_CTRL_VS_IL35_TREATED_TCONV_CD4_TCELL_UP | MSigDB lists | GSE24210_CTRL_VS_IL35_TREATED_TCONV_CD4_TCELL_UP | 189 | 8 | 17377 | 282 |
ARHGAP26,STRADB,SLC40A1,UROS,EHD3,RERE,NUAK2,SPATA13 |
| 1.220e-02 | -4.41 | YOSHIMURA_MAPK8_TARGETS_DN | MSigDB lists | YOSHIMURA_MAPK8_TARGETS_DN | 350 | 12 | 17377 | 282 |
BDNF,ACVR1,ACSL1,PDK1,SLC30A4,MAP2K6,MYC,ALDOA,P4HA1,PRICKLE2,ABAT,NEO1 |
| 1.222e-02 | -4.40 | limb bud formation | biological process | GO:0060174 | 11 | 2 | 17256 | 270 |
ZNF219,PLXNA2 |
| 1.222e-02 | -4.40 | positive regulation of cytolysis | biological process | GO:0045919 | 11 | 2 | 17256 | 270 |
CFHR1,GPLD1 |
| 1.222e-02 | -4.40 | ER overload response | biological process | GO:0006983 | 11 | 2 | 17256 | 270 |
WFS1,DDIT3 |
| 1.222e-02 | -4.40 | forebrain neuron fate commitment | biological process | GO:0021877 | 11 | 2 | 17256 | 270 |
SATB2,DLX2 |
| 1.222e-02 | -4.40 | endocardium development | biological process | GO:0003157 | 11 | 2 | 17256 | 270 |
OVOL2,ACVR1 |
| 1.226e-02 | -4.40 | thyroid-other-neoplasm | COSMIC cancer mutations | thyroid-other-neoplasm | 7848 | 146 | 17385 | 281 |
ARHGAP26,DUSP8,LGR4,RECK,HEBP1,LSM11,PTPN21,ALG1L,NDRG2,CEBPA,ITPR2,SLC2A13,PRKCA,HMCN1,EPDR1,CPNE2,PPM1E,PMAIP1,CFHR1,TMEM143,TLN2,OR2W3,TSHR,PGBD5,TBC1D8,PNRC1,KLHL23,KLHL3,WISP3,CAPN5,ABCC2,TNS1,ACVR2B,SGK2,SPNS1,DYRK1B,PLK2,ERN1,MAPK13,LONRF1,SCN5A,TMEM63C,RUNX2,ZNF395,ZHX3,CYP4V2,SETBP1,RASL11B,TNFRSF10C,HPCAL4,FHOD3,MTUS1,IL17D,NUMBL,SLC30A4,ZIC5,SRGAP1,GAN,EBF4,MOXD1,NCEH1,VGLL4,GPR161,EPB41L5,QSOX1,SPATA13,PPFIA4,WDR25,WWC1,SHISA2,PRDM1,LHPP,ARRDC4,B4GALNT3,KIAA0355,ADAMTS3,EMILIN2,HK2,IQSEC2,RNF122,SMYD3,ZNF516,DOCK1,ST14,CCDC110,FAM131C,C4A,PLXNA2,RHPN2,COLEC10,KIF21B,RADIL,TIAM2,ZNF827,KMO,RPS6KL1,EEPD1,ZNF521,MAP7,MYH15,TMEM120B,DNAH5,DZANK1,GAPDH,CYB5R2,SOX21,ADCY1,NLGN4X,WNT11,SATB2,RAB38,CENPV,IFT81,ANKRD31,WFS1,PLEKHG1,DISP1,KLHL31,COBL,CCDC148,TMEM132C,ARHGEF11,KIF5C,ZNF219,NEO1,GPR155,PRKCD,RASD2,TRIM3,KIAA0408,PARP9,TMC7,MN1,B9D1,PXN,OGDHL,PALLD,TLR6,GPR137C,GPLD1,RERE,KIAA0513,MYOM2,THAP10,RNF157,PHC1 |
| 1.229e-02 | -4.40 | GO_NEGATIVE_REGULATION_OF_RESPONSE_TO_STIMULUS | MSigDB lists | GO_NEGATIVE_REGULATION_OF_RESPONSE_TO_STIMULUS | 1302 | 32 | 17377 | 282 |
RGS16,ACVR1,RUNX2,RASAL2,DUSP8,LGR4,UBASH3B,RASL11B,NDRG2,OVOL2,GAS6,ABAT,RGS17,DACT1,MYC,PRKCD,DAB2IP,BARX1,GPR161,PHLDB2,QSOX1,PTPN6,STRADB,WWC1,NLGN4X,WNT11,PLEKHA1,PRDM1,WFS1,WWTR1,DLX2,DDIT3 |
| 1.232e-02 | -4.40 | embryonic forelimb morphogenesis | biological process | GO:0035115 | 31 | 3 | 17256 | 270 |
MSX1,RUNX2,RECK |
| 1.232e-02 | -4.40 | hippo signaling | biological process | GO:0035329 | 31 | 3 | 17256 | 270 |
WWC1,SAV1,WWTR1 |
| 1.235e-02 | -4.39 | regulation of fibroblast proliferation | biological process | GO:0048145 | 88 | 5 | 17256 | 270 |
DAB2IP,GAS6,FBXO4,MYC,B4GALT7 |
| 1.239e-02 | -4.39 | GO_PROTEIN_KINASE_ACTIVITY | MSigDB lists | GO_PROTEIN_KINASE_ACTIVITY | 618 | 18 | 17377 | 282 |
ACVR1,PDK1,NUAK2,EFNA3,STRADB,ACVR2B,PRKCA,SGK2,DYRK1B,FGR,PLK2,RPS6KL1,MAP2K6,ERN1,PRKCD,SGK1,MAPK13,EPHB6 |
| 1.240e-02 | -4.39 | TIAM1 (T cell lymphoma invasion and metastasis 1) | protein interactions | 7074 | 83 | 5 | 17029 | 283 |
PHLDB2,RASAL2,PRKCA,MYC,PRKCD |
| 1.242e-02 | -4.39 | MODULE_221 | MSigDB lists | MODULE_221 | 30 | 3 | 17377 | 282 |
ABAT,ACSL1,BLVRB |
| 1.242e-02 | -4.39 | PID_RAS_PATHWAY | MSigDB lists | PID_RAS_PATHWAY | 30 | 3 | 17377 | 282 |
DAB2IP,PRKCA,RASGRF2 |
| 1.242e-02 | -4.39 | GO_BICELLULAR_TIGHT_JUNCTION_ASSEMBLY | MSigDB lists | GO_BICELLULAR_TIGHT_JUNCTION_ASSEMBLY | 30 | 3 | 17377 | 282 |
ARL2,WNT11,MARVELD2 |
| 1.245e-02 | -4.39 | BASAKI_YBX1_TARGETS_DN | MSigDB lists | BASAKI_YBX1_TARGETS_DN | 351 | 12 | 17377 | 282 |
C2orf88,SLC40A1,MXI1,PDK1,SCAMP1,HK2,P4HA1,PLEKHA1,TMEM37,DBP,SGK2,SMPDL3A |
| 1.249e-02 | -4.38 | AATGTGA,MIR-23A,MIR-23B | MSigDB lists | AATGTGA,MIR-23A,MIR-23B | 394 | 13 | 17377 | 282 |
RUNX2,ZNF395,LGR4,RBPMS2,NUAK2,BNIP3L,SGK1,SATB2,PRDM1,PALLD,SATB1,PKIA,MTUS1 |
| 1.251e-02 | -4.38 | GO_EMBRYONIC_MORPHOGENESIS | MSigDB lists | GO_EMBRYONIC_MORPHOGENESIS | 527 | 16 | 17377 | 282 |
B9D1,EPB41L5,MSX1,ACVR1,RUNX2,ST14,RECK,MAFB,SATB2,WNT11,ACVR2B,OVOL2,DACT1,DLX6,DLX2,COBL |
| 1.254e-02 | -4.38 | striated muscle cell differentiation | biological process | GO:0051146 | 197 | 8 | 17256 | 270 |
DYRK1B,ACVR1,BVES,TMOD2,MYOM2,SMYD3,FHOD3,MYORG |
| 1.254e-02 | -4.38 | ACCATTT,MIR-522 | MSigDB lists | ACCATTT,MIR-522 | 153 | 7 | 17377 | 282 |
MAFB,PPM1E,CEBPA,KIAA0355,PLK2,GNAO1,TBC1D8 |
| 1.254e-02 | -4.38 | CONCANNON_APOPTOSIS_BY_EPOXOMICIN_DN | MSigDB lists | CONCANNON_APOPTOSIS_BY_EPOXOMICIN_DN | 153 | 7 | 17377 | 282 |
MXI1,PDK1,MAP2K6,MYC,MTUS1,ADCY1,HK2 |
| 1.255e-02 | -4.38 | salivary_gland | COSMIC cancer mutations | salivary_gland | 1157 | 29 | 17385 | 281 |
IL17RD,CCDC148,RUNX2,ACVR1,ZNF395,PDK1,SPATA13,ACVR2B,PRKCA,PALLD,CBLN1,NEO1,ZNF827,FKBP9,TRIB3,FGR,LMLN,PLK2,MAP2K6,RPS6KL1,HK2,SGK1,MAPK13,MYOM2,KLHL31,TANC2,DNAH5,OR2W3,DDIT3 |
| 1.255e-02 | -4.38 | GSE360_HIGH_DOSE_B_MALAYI_VS_M_TUBERCULOSIS_MAC_DN | MSigDB lists | GSE360_HIGH_DOSE_B_MALAYI_VS_M_TUBERCULOSIS_MAC_DN | 190 | 8 | 17377 | 282 |
RGS16,ACSL1,PDK1,SLC30A4,SLC39A8,KIF5C,PDE4D,IQSEC2 |
| 1.255e-02 | -4.38 | GSE32986_CURDLAN_LOWDOSE_VS_CURDLAN_HIGHDOSE_STIM_DC_DN | MSigDB lists | GSE32986_CURDLAN_LOWDOSE_VS_CURDLAN_HIGHDOSE_STIM_DC_DN | 190 | 8 | 17377 | 282 |
FGR,ZNF516,PNRC1,RBPMS2,PLXNA2,PRDM1,ABHD6,TMEM120B |
| 1.255e-02 | -4.38 | GSE15735_CTRL_VS_HDAC_INHIBITOR_TREATED_CD4_TCELL_2H_UP | MSigDB lists | GSE15735_CTRL_VS_HDAC_INHIBITOR_TREATED_CD4_TCELL_2H_UP | 190 | 8 | 17377 | 282 |
PPM1E,FGR,MARVELD2,PTPN6,CAPN5,PRKCD,NUAK2,RNF157 |
| 1.255e-02 | -4.38 | GSE24142_DN2_VS_DN3_THYMOCYTE_FETAL_DN | MSigDB lists | GSE24142_DN2_VS_DN3_THYMOCYTE_FETAL_DN | 190 | 8 | 17377 | 282 |
SLC30A4,SCAMP1,RPS6KL1,ITPR2,DBP,ARRDC4,TMEM120B,CBLN1 |
| 1.255e-02 | -4.38 | GSE31082_DN_VS_CD8_SP_THYMOCYTE_DN | MSigDB lists | GSE31082_DN_VS_CD8_SP_THYMOCYTE_DN | 190 | 8 | 17377 | 282 |
RGS16,ARHGEF11,RECK,GPR155,PJA1,HERC6,ABHD6,RERE |
| 1.255e-02 | -4.38 | GO_CONNECTIVE_TISSUE_DEVELOPMENT | MSigDB lists | GO_CONNECTIVE_TISSUE_DEVELOPMENT | 190 | 8 | 17377 | 282 |
DYRK1B,MSX1,ZNF516,RUNX2,ACTA2,SATB2,DLX2,GPLD1 |
| 1.258e-02 | -4.38 | negative regulation of response to stimulus | biological process | GO:0048585 | 1621 | 37 | 17256 | 270 |
RGS16,RUNX2,ACVR1,DUSP8,LGR4,RASAL2,UBASH3B,RASL11B,NDRG2,GAS6,ABAT,CBLN1,RGS17,DACT1,MYC,PRKCD,DAB2IP,EPHB6,BARX1,GPR161,PHLDB2,PTPN6,STRADB,WWC1,NLGN4X,SHISA2,WNT11,PRDM1,PLEKHA1,TLR6,TRIB3,RBPMS2,WFS1,PLK2,WWTR1,DLX2,DDIT3 |
| 1.258e-02 | -4.38 | TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_16D_DN | MSigDB lists | TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_16D_DN | 118 | 6 | 17377 | 282 |
CPNE2,TNS1,TMEM37,KIF21B,RASAL2,MTUS1 |
| 1.258e-02 | -4.38 | RB_DN.V1_DN | MSigDB lists | RB_DN.V1_DN | 118 | 6 | 17377 | 282 |
P4HA1,RASL11B,UROS,MOXD1,DDIT3,PLXNA2 |
| 1.264e-02 | -4.37 | kidney-carcinoma-papillary_renal_cell_carcinoma | COSMIC cancer mutations | kidney-carcinoma-papillary_renal_cell_carcinoma | 6518 | 124 | 17385 | 281 |
ARHGAP26,ACSL1,ZNF516,ACVR1,LGR4,DOCK1,ST14,HEBP1,CCDC110,PLXNA2,RHPN2,CEBPA,SLC2A13,ITPR2,FAM198B,COLEC10,PRKCA,KIF21B,ABHD6,RADIL,HMCN1,TMEM53,RPS6KL1,ZNF521,DAB2IP,MYH15,PJA1,TLN2,DNAH5,TMEM120B,HSPA2,TBC1D8,DZANK1,PNRC1,PDK1,KLHL3,SLC39A8,CAPN5,ADCY1,NLGN4X,SLC25A28,SATB2,TNS1,ABCC2,RAB38,ACVR2B,SGK2,SAV1,NT5DC2,SPNS1,DYRK1B,SPATA9,IFT81,TCF7L1,LMLN,PLK2,WFS1,ERN1,PLEKHG1,P4HA1,TNFSF15,MAPK13,KLHL31,TANC2,APBA2,TMEM132C,RUNX2,ZNF395,PRSS16,BVES,BACE1,BIK,SETBP1,KIF5C,ARL2,CHADL,SLC36A4,DYNC1I1,SATB1,NIPSNAP3B,FHOD3,NEO1,MTUS1,RGS17,GPR155,PRKCD,GAN,SRGAP1,TRIM3,PRICKLE2,SGK1,MOXD1,STXBP1,VGLL4,TMC7,MN1,IL17RD,SLC40A1,MPP1,NUAK2,SPATA13,PPFIA4,WWC1,STRADB,SHISA2,PALLD,B4GALNT3,GPR137C,ZNF558,RERE,GPLD1,TRIB3,FGR,KIAA0355,ADAMTS3,MAP2K6,FMO4,EMILIN2,CLMN,KIAA0513,MYOM2,ZNF474,IQSEC2,RNF157 |
| 1.264e-02 | -4.37 | papillary_renal_cell_carcinoma | COSMIC cancer mutations | papillary_renal_cell_carcinoma | 6518 | 124 | 17385 | 281 |
ARHGAP26,ACSL1,ZNF516,ACVR1,LGR4,DOCK1,ST14,HEBP1,CCDC110,PLXNA2,RHPN2,CEBPA,SLC2A13,ITPR2,FAM198B,COLEC10,PRKCA,KIF21B,ABHD6,RADIL,HMCN1,TMEM53,RPS6KL1,ZNF521,DAB2IP,MYH15,PJA1,TLN2,DNAH5,TMEM120B,HSPA2,TBC1D8,DZANK1,PNRC1,PDK1,KLHL3,SLC39A8,CAPN5,ADCY1,NLGN4X,SLC25A28,SATB2,TNS1,ABCC2,RAB38,ACVR2B,SGK2,SAV1,NT5DC2,SPNS1,DYRK1B,SPATA9,IFT81,TCF7L1,LMLN,PLK2,WFS1,ERN1,PLEKHG1,P4HA1,TNFSF15,MAPK13,KLHL31,TANC2,APBA2,TMEM132C,RUNX2,ZNF395,PRSS16,BVES,BACE1,BIK,SETBP1,KIF5C,ARL2,CHADL,SLC36A4,DYNC1I1,SATB1,NIPSNAP3B,FHOD3,NEO1,MTUS1,RGS17,GPR155,PRKCD,GAN,SRGAP1,TRIM3,PRICKLE2,SGK1,MOXD1,STXBP1,VGLL4,TMC7,MN1,IL17RD,SLC40A1,MPP1,NUAK2,SPATA13,PPFIA4,WWC1,STRADB,SHISA2,PALLD,B4GALNT3,GPR137C,ZNF558,RERE,GPLD1,TRIB3,FGR,KIAA0355,ADAMTS3,MAP2K6,FMO4,EMILIN2,CLMN,KIAA0513,MYOM2,ZNF474,IQSEC2,RNF157 |
| 1.264e-02 | -4.37 | human chr12q24.32-q24.33 | chromosome location | human chr12q24.32-q24.33 | 1 | 1 | 26185 | 331 |
TMEM132C |
| 1.264e-02 | -4.37 | human chr15q21.1|15q21.1 | chromosome location | human chr15q21.1|15q21.1 | 1 | 1 | 26185 | 331 |
SLC30A4 |
| 1.264e-02 | -4.37 | human chr5q11.2-q12.1 | chromosome location | human chr5q11.2-q12.1 | 1 | 1 | 26185 | 331 |
PDE4D |
| 1.264e-02 | -4.37 | human chrXp22.32-p22.31 | chromosome location | human chrXp22.32-p22.31 | 1 | 1 | 26185 | 331 |
NLGN4X |
| 1.264e-02 | -4.37 | human chr3p25.3-p25.2 | chromosome location | human chr3p25.3-p25.2 | 1 | 1 | 26185 | 331 |
VGLL4 |
| 1.264e-02 | -4.37 | human chr4q35.1-q35.2 | chromosome location | human chr4q35.1-q35.2 | 1 | 1 | 26185 | 331 |
CYP4V2 |
| 1.264e-02 | -4.37 | human chr2p21|2p16-p12 | chromosome location | human chr2p21|2p16-p12 | 1 | 1 | 26185 | 331 |
ATP6V1E2 |
| 1.264e-02 | -4.37 | human chr2q23.1-q23.2 | chromosome location | human chr2q23.1-q23.2 | 1 | 1 | 26185 | 331 |
KIF5C |
| 1.264e-02 | -4.37 | human chr18p11.32-p11.31 | chromosome location | human chr18p11.32-p11.31 | 1 | 1 | 26185 | 331 |
EMILIN2 |
| 1.264e-02 | -4.37 | human chr17q23.2-q23.3 | chromosome location | human chr17q23.2-q23.3 | 1 | 1 | 26185 | 331 |
TANC2 |
| 1.264e-02 | -4.37 | human chr6q25.2-q25.3 | chromosome location | human chr6q25.2-q25.3 | 1 | 1 | 26185 | 331 |
TIAM2 |
| 1.264e-02 | -4.37 | human chr4q31.21-q31.22 | chromosome location | human chr4q31.21-q31.22 | 1 | 1 | 26185 | 331 |
ZNF827 |
| 1.264e-02 | -4.37 | human chr1q25.3-q31.1 | chromosome location | human chr1q25.3-q31.1 | 1 | 1 | 26185 | 331 |
HMCN1 |
| 1.265e-02 | -4.37 | embryo development | biological process | GO:0009790 | 889 | 23 | 17256 | 270 |
EPB41L5,B9D1,MSX1,RUNX2,ACVR1,ST14,RECK,PLXNA2,MAFB,SATB2,CEBPA,WNT11,PRDM1,ACVR2B,OVOL2,DACT1,DLX6,RBPMS2,DISP1,DLX2,TANC2,APBA2,COBL |
| 1.273e-02 | -4.36 | MORF_CAMK4 | MSigDB lists | MORF_CAMK4 | 269 | 10 | 17377 | 282 |
PPM1E,PDE4D,RUNX2,TANC2,PRKCA,WISP3,KLHL23,SMYD3,PLEKHB1,GPLD1 |
| 1.274e-02 | -4.36 | site of polarized growth | cellular component | GO:0030427 | 162 | 7 | 18223 | 280 |
KIF5C,NDRG2,TMOD2,KIF21B,PALLD,COBL,TIAM2 |
| 1.281e-02 | -4.36 | myofilament | cellular component | GO:0036379 | 32 | 3 | 18223 | 280 |
MYOM2,TMOD2,FHOD3 |
| 1.286e-02 | -4.35 | stomach-carcinoma | COSMIC cancer mutations | stomach-carcinoma | 441 | 14 | 17385 | 281 |
DYRK1B,TRIB3,FGR,ACVR1,PDK1,PLK2,MAP2K6,RPS6KL1,PRKCD,NUAK2,SGK1,STRADB,MAPK13,PRKCA |
| 1.288e-02 | -4.35 | GO_POSITIVE_REGULATION_OF_RESPONSE_TO_DNA_DAMAGE_STIMULUS | MSigDB lists | GO_POSITIVE_REGULATION_OF_RESPONSE_TO_DNA_DAMAGE_STIMULUS | 56 | 4 | 17377 | 282 |
MSX1,PMAIP1,MYC,PRKCD |
| 1.288e-02 | -4.35 | DAVICIONI_PAX_FOXO1_SIGNATURE_IN_ARMS_UP | MSigDB lists | DAVICIONI_PAX_FOXO1_SIGNATURE_IN_ARMS_UP | 56 | 4 | 17377 | 282 |
SGK1,MN1,ABAT,PRKCA |
| 1.288e-02 | -4.35 | GO_EMBRYONIC_PATTERN_SPECIFICATION | MSigDB lists | GO_EMBRYONIC_PATTERN_SPECIFICATION | 56 | 4 | 17377 | 282 |
EPB41L5,SATB2,DISP1,COBL |
| 1.292e-02 | -4.35 | GSE5503_PLN_DC_VS_SPLEEN_DC_ACTIVATED_ALLOGENIC_TCELL_UP | MSigDB lists | GSE5503_PLN_DC_VS_SPLEEN_DC_ACTIVATED_ALLOGENIC_TCELL_UP | 191 | 8 | 17377 | 282 |
WWC1,B9D1,MXI1,GAPDH,DOCK1,PRKCD,TIAM2,HK2 |
| 1.292e-02 | -4.35 | GSE22443_NAIVE_VS_ACT_AND_IL12_TREATED_CD8_TCELL_UP | MSigDB lists | GSE22443_NAIVE_VS_ACT_AND_IL12_TREATED_CD8_TCELL_UP | 191 | 8 | 17377 | 282 |
SPNS1,FGR,MXI1,MPP1,PRKCD,EEPD1,TLR6,CENPV |
| 1.292e-02 | -4.35 | GSE2405_HEAT_KILLED_LYSATE_VS_LIVE_A_PHAGOCYTOPHILUM_STIM_NEUTROPHIL_24H_DN | MSigDB lists | GSE2405_HEAT_KILLED_LYSATE_VS_LIVE_A_PHAGOCYTOPHILUM_STIM_NEUTROPHIL_24H_DN | 191 | 8 | 17377 | 282 |
EPCAM,CPNE2,PLK2,PTPN21,PLEKHG1,RAB38,STXBP1,NEO1 |
| 1.292e-02 | -4.35 | GSE32034_LY6C_HIGH_VS_LOW_MONOCYTE_UP | MSigDB lists | GSE32034_LY6C_HIGH_VS_LOW_MONOCYTE_UP | 191 | 8 | 17377 | 282 |
FKBP9,FGR,ACSL1,RUNX2,PRSS16,ERN1,RHPN2,PRDM1 |
| 1.292e-02 | -4.35 | GSE26488_WT_VS_HDAC7_DELTAP_TG_OT2_THYMOCYTE_WITH_PEPTIDE_INJECTION_UP | MSigDB lists | GSE26488_WT_VS_HDAC7_DELTAP_TG_OT2_THYMOCYTE_WITH_PEPTIDE_INJECTION_UP | 191 | 8 | 17377 | 282 |
MAFB,RGS16,WNT11,ABCC2,MAP2K6,SMPDL3A,PKIA,HK2 |
| 1.292e-02 | -4.35 | GSE22935_24H_VS_48H_MBOVIS_BCG_STIM_MYD88_KO_MACROPHAGE_UP | MSigDB lists | GSE22935_24H_VS_48H_MBOVIS_BCG_STIM_MYD88_KO_MACROPHAGE_UP | 191 | 8 | 17377 | 282 |
SLC25A28,FKBP9,RAB38,RUNX2,SAV1,MPP1,SMPDL3A,PARP9 |
| 1.292e-02 | -4.35 | GOLDRATH_NAIVE_VS_EFF_CD8_TCELL_UP | MSigDB lists | GOLDRATH_NAIVE_VS_EFF_CD8_TCELL_UP | 191 | 8 | 17377 | 282 |
MAP7,ITPR2,PLEKHA1,PDK1,SATB1,MPP1,PTPN6,RERE |
| 1.292e-02 | -4.35 | GSE40068_CXCR5NEG_BCL6NEG_CD4_TCELL_VS_CXCR5POS_BCL6NEG_TFH_DN | MSigDB lists | GSE40068_CXCR5NEG_BCL6NEG_CD4_TCELL_VS_CXCR5POS_BCL6NEG_TFH_DN | 191 | 8 | 17377 | 282 |
ARHGAP26,ST14,RECK,GPR155,ERN1,KIF5C,TMEM37,RNF157 |
| 1.292e-02 | -4.35 | GSE17721_CTRL_VS_LPS_6H_BMDC_DN | MSigDB lists | GSE17721_CTRL_VS_LPS_6H_BMDC_DN | 191 | 8 | 17377 | 282 |
ACVR1,PALLD,STXBP1,CYP2J2,SLC39A8,MPP1,WFS1,HK2 |
| 1.292e-02 | -4.35 | GSE13484_12H_UNSTIM_VS_YF17D_VACCINE_STIM_PBMC_DN | MSigDB lists | GSE13484_12H_UNSTIM_VS_YF17D_VACCINE_STIM_PBMC_DN | 191 | 8 | 17377 | 282 |
PMAIP1,CYP2J2,ATOX1,HK2,ABCC2,PALLD,SAV1,HSPA2 |
| 1.297e-02 | -4.35 | Toll-like receptor binding | molecular function | GO:0035325 | 11 | 2 | 17224 | 278 |
DAB2IP,TLR6 |
| 1.297e-02 | -4.35 | iron ion transmembrane transporter activity | molecular function | GO:0005381 | 11 | 2 | 17224 | 278 |
SLC40A1,SLC25A28 |
| 1.301e-02 | -4.34 | GO_POSITIVE_REGULATION_OF_CAMP_METABOLIC_PROCESS | MSigDB lists | GO_POSITIVE_REGULATION_OF_CAMP_METABOLIC_PROCESS | 86 | 5 | 17377 | 282 |
PRKCA,TSHR,WFS1,GPR161,ADCY1 |
| 1.301e-02 | -4.34 | GO_RECEPTOR_SIGNALING_PROTEIN_SERINE_THREONINE_KINASE_ACTIVITY | MSigDB lists | GO_RECEPTOR_SIGNALING_PROTEIN_SERINE_THREONINE_KINASE_ACTIVITY | 86 | 5 | 17377 | 282 |
STRADB,MAPK13,ACVR2B,ACVR1,MAP2K6 |
| 1.302e-02 | -4.34 | embryonic organ morphogenesis | biological process | GO:0048562 | 280 | 10 | 17256 | 270 |
MSX1,ACVR1,RUNX2,DLX6,RBPMS2,MAFB,WNT11,SATB2,OVOL2,DLX2 |
| 1.310e-02 | -4.33 | HOLLEMAN_PREDNISOLONE_RESISTANCE_B_ALL_DN | MSigDB lists | HOLLEMAN_PREDNISOLONE_RESISTANCE_B_ALL_DN | 11 | 2 | 17377 | 282 |
GAPDH,BLVRB |
| 1.310e-02 | -4.33 | GO_ENDOCARDIUM_DEVELOPMENT | MSigDB lists | GO_ENDOCARDIUM_DEVELOPMENT | 11 | 2 | 17377 | 282 |
OVOL2,ACVR1 |
| 1.310e-02 | -4.33 | GO_REGULATION_OF_CELLULAR_RESPONSE_TO_VASCULAR_ENDOTHELIAL_GROWTH_FACTOR_STIMULUS | MSigDB lists | GO_REGULATION_OF_CELLULAR_RESPONSE_TO_VASCULAR_ENDOTHELIAL_GROWTH_FACTOR_STIMULUS | 11 | 2 | 17377 | 282 |
DAB2IP,ADAMTS3 |
| 1.310e-02 | -4.33 | GO_PROTON_TRANSPORTING_TWO_SECTOR_ATPASE_COMPLEX_CATALYTIC_DOMAIN | MSigDB lists | GO_PROTON_TRANSPORTING_TWO_SECTOR_ATPASE_COMPLEX_CATALYTIC_DOMAIN | 11 | 2 | 17377 | 282 |
ATP6V1E2,ATP6AP1L |
| 1.311e-02 | -4.33 | RAP2A (RAP2A, member of RAS oncogene family) | protein interactions | 5911 | 55 | 4 | 17029 | 283 |
SGK1,ACVR1,SLC30A4,MARVELD2 |
| 1.311e-02 | -4.33 | PFN2 (profilin 2) | protein interactions | 5217 | 55 | 4 | 17029 | 283 |
ACTA2,PALLD,PFN2,BLVRB |
| 1.315e-02 | -4.33 | ruffle membrane | cellular component | GO:0032587 | 91 | 5 | 18223 | 280 |
WWC1,EPB41L5,FGR,PLEKHA1,SPATA13 |
| 1.324e-02 | -4.32 | CLN8 (CLN8, transmembrane ER and ERGIC protein) | protein interactions | 2055 | 30 | 3 | 17029 | 283 |
NDRG2,BNIP3,BNIP3L |
| 1.324e-02 | -4.32 | CTU1 (cytosolic thiouridylase subunit 1) | protein interactions | 90353 | 30 | 3 | 17029 | 283 |
CCNJL,UROS,GAN |
| 1.329e-02 | -4.32 | GO_TRANSCRIPTIONAL_ACTIVATOR_ACTIVITY_RNA_POLYMERASE_II_TRANSCRIPTION_REGULATORY_REGION_SEQUENCE_SPECIFIC_BINDING | MSigDB lists | GO_TRANSCRIPTIONAL_ACTIVATOR_ACTIVITY_RNA_POLYMERASE_II_TRANSCRIPTION_REGULATORY_REGION_SEQUENCE_SPECIFIC_BINDING | 312 | 11 | 17377 | 282 |
MSX1,RUNX2,MYC,EBF4,MAFB,CEBPA,OVOL2,DBP,DLX2,BARX1,DDIT3 |
| 1.330e-02 | -4.32 | GSE18893_TCONV_VS_TREG_24H_CULTURE_DN | MSigDB lists | GSE18893_TCONV_VS_TREG_24H_CULTURE_DN | 192 | 8 | 17377 | 282 |
MAP7,TANC2,SLC30A4,PNRC1,SATB1,KMO,RNF157,MPP1 |
| 1.330e-02 | -4.32 | GSE3982_DC_VS_CENT_MEMORY_CD4_TCELL_UP | MSigDB lists | GSE3982_DC_VS_CENT_MEMORY_CD4_TCELL_UP | 192 | 8 | 17377 | 282 |
FGR,KMO,NDRG2,P4HA1,RAB38,ABHD6,TBC1D16,STXBP1 |
| 1.330e-02 | -4.32 | GSE29618_MONOCYTE_VS_MDC_DAY7_FLU_VACCINE_UP | MSigDB lists | GSE29618_MONOCYTE_VS_MDC_DAY7_FLU_VACCINE_UP | 192 | 8 | 17377 | 282 |
MXI1,ACSL1,MPP1,BNIP3L,CLMN,KIAA0513,FAM198B,SMPDL3A |
| 1.342e-02 | -4.31 | BRLZ | smart domains | SM00338 | 51 | 4 | 9493 | 172 |
MAFB,CEBPA,DBP,DDIT3 |
| 1.350e-02 | -4.31 | regulation of phosphate metabolic process | biological process | GO:0019220 | 1792 | 40 | 17256 | 270 |
ACSL1,ACVR1,NECAB2,DUSP8,UBASH3B,NDRG2,CEBPA,GAS6,TNFRSF10C,PRKCA,PFN2,PPM1E,DACT1,MYC,PRKCD,INAVA,DAB2IP,PDE4D,EPHB6,TSHR,HSPA2,GPR161,PARP9,PTPN6,ADCY1,WWC1,STRADB,WNT11,GAREM1,ACVR2B,TLR6,GPLD1,TRIB3,FGR,MAP2K6,WWTR1,ERN1,TNFSF15,SMYD3,PKIA |
| 1.351e-02 | -4.30 | endothelium development | biological process | GO:0003158 | 90 | 5 | 17256 | 270 |
SLC40A1,PDE4D,ACVR2B,ACVR1,MARVELD2 |
| 1.358e-02 | -4.30 | GTGCAAA,MIR-507 | MSigDB lists | GTGCAAA,MIR-507 | 120 | 6 | 17377 | 282 |
LONRF1,RGS17,DAB2IP,PRDM1,IQSEC2,EMILIN2 |
| 1.358e-02 | -4.30 | TGCTTTG,MIR-330 | MSigDB lists | TGCTTTG,MIR-330 | 313 | 11 | 17377 | 282 |
PPM1E,ACVR1,RUNX2,DLX6,SOX21,GNAO1,PLXNA2,EFNA3,TRIM3,NCEH1,ABHD4 |
| 1.359e-02 | -4.30 | GRADE_COLON_CANCER_DN | MSigDB lists | GRADE_COLON_CANCER_DN | 31 | 3 | 17377 | 282 |
SGK1,C2orf88,MXI1 |
| 1.359e-02 | -4.30 | PID_P38_ALPHA_BETA_PATHWAY | MSigDB lists | PID_P38_ALPHA_BETA_PATHWAY | 31 | 3 | 17377 | 282 |
FGR,DUSP8,MAP2K6 |
| 1.359e-02 | -4.30 | BCAT.100_UP.V1_DN | MSigDB lists | BCAT.100_UP.V1_DN | 31 | 3 | 17377 | 282 |
TLN2,RALGPS2,WISP3 |
| 1.359e-02 | -4.30 | GO_EMBRYONIC_FORELIMB_MORPHOGENESIS | MSigDB lists | GO_EMBRYONIC_FORELIMB_MORPHOGENESIS | 31 | 3 | 17377 | 282 |
MSX1,RUNX2,RECK |
| 1.366e-02 | -4.29 | ovary-carcinoma-serous_carcinoma | COSMIC cancer mutations | ovary-carcinoma-serous_carcinoma | 11013 | 196 | 17385 | 281 |
ARHGAP26,CCDC126,ACSL1,ACVR1,LGR4,RECK,PTPN21,ALG1L,SLC2A13,ITPR2,PRKCA,CACNB4,ABHD6,HMCN1,NCS1,EPDR1,CPNE2,FKBP9,PPM1E,DLX6,MARVELD2,CFHR1,TMEM37,TLN2,OR2W3,TSHR,FANK1,TBC1D8,PGBD5,KLHL3,DSTN,CAPN5,ABCC2,TNS1,PLEKHA1,ACVR2B,SGK2,PLEKHB1,DYRK1B,TCF7L1,PLK2,RASGRF2,ERN1,ALDOA,ARHGAP28,MAPK13,TMOD2,DLX2,TANC2,APBA2,LONRF1,GPR63,SCN5A,TMEM63C,RGS16,RUNX2,UBASH3B,CYP2J2,SETBP1,RASL11B,ATP6V1E2,SLC36A4,PFN2,SATB1,DYNC1I1,FHOD3,MTUS1,NUMBL,MYC,ZIC5,EBF4,SRGAP1,GAN,NCEH1,MOXD1,VGLL4,STXBP1,GPR161,EPB41L5,IL17RD,QSOX1,SPATA13,PPFIA4,WWC1,STRADB,SHISA2,PRDM1,OR11H4,B4GALNT3,ZNF558,ADAMTS3,KIAA0355,LRRIQ3,EMILIN2,HK2,CLMN,IQSEC2,RNF122,ZNF516,RASAL2,DOCK1,ST14,C4A,PLXNA2,RHPN2,COLEC10,KIF21B,CBLN1,TIAM2,ZNF827,TMEM53,KMO,RPS6KL1,DACT1,ZNF521,EEPD1,ZDHHC23,DAB2IP,MYH15,PJA1,PDE4D,DNAH5,TMEM120B,FAM78B,HSPA2,PHLDB2,GAPDH,UROS,PDK1,SFXN4,ADCY1,NLGN4X,SATB2,WNT11,TBC1D16,JAM3,IQCK,IFT81,LMLN,ZNF697,WFS1,WWTR1,PLEKHG1,P4HA1,DISP1,KLHL31,COBL,KCTD1,CCDC148,NECAB2,PRSS16,ARHGEF11,BACE1,BIK,GAS6,OVOL2,ZNF219,NEO1,GPR155,PRKCD,RASD2,EHD3,GTF2F2,PRICKLE2,TRIM3,SGK1,KIAA0408,SMPDL3A,PARP9,TMC7,MN1,SLC40A1,MSX1,PXN,MPP1,OGDHL,NUAK2,EXOG,PALLD,TLR6,GPR137C,RERE,GPLD1,CTIF,TRIB3,FGR,FMO4,MAP2K6,KIAA0513,MYOM2,THAP10,RNF157,PKIA,DDIT3,B4GALT7,PHC1 |
| 1.368e-02 | -4.29 | GO_NUCLEOTIDE_PHOSPHORYLATION | MSigDB lists | GO_NUCLEOTIDE_PHOSPHORYLATION | 57 | 4 | 17377 | 282 |
GAPDH,ALDOA,OGDHL,HK2 |
| 1.369e-02 | -4.29 | GSE28737_WT_VS_BCL6_KO_FOLLICULAR_BCELL_DN | MSigDB lists | GSE28737_WT_VS_BCL6_KO_FOLLICULAR_BCELL_DN | 193 | 8 | 17377 | 282 |
PRDM1,ABHD4,RNF122,PFN2,HEBP1,GPR155,PRKCD,SPATA13 |
| 1.369e-02 | -4.29 | GSE28237_EARLY_VS_LATE_GC_BCELL_UP | MSigDB lists | GSE28237_EARLY_VS_LATE_GC_BCELL_UP | 193 | 8 | 17377 | 282 |
CPNE2,IFT81,SLC30A4,RASD2,BIK,PLEKHG1,ZNF474,FAM198B |
| 1.369e-02 | -4.29 | V$CEBP_C | MSigDB lists | V$CEBP_C | 193 | 8 | 17377 | 282 |
BDNF,ACVR1,PDE4D,SAV1,MAP2K6,ALDOA,RERE,GPLD1 |
| 1.369e-02 | -4.29 | GSE2585_CTEC_VS_THYMIC_DC_DN | MSigDB lists | GSE2585_CTEC_VS_THYMIC_DC_DN | 193 | 8 | 17377 | 282 |
BDNF,LSM11,PTPN6,ALDOA,SHISA2,ARRDC4,RNF157,FAM78B |
| 1.369e-02 | -4.29 | GSE3039_CD4_TCELL_VS_B1_BCELL_UP | MSigDB lists | GSE3039_CD4_TCELL_VS_B1_BCELL_UP | 193 | 8 | 17377 | 282 |
RASL11B,ITPR2,TANC2,PALLD,STXBP1,KMO,CFHR1,NCS1 |
| 1.369e-02 | -4.29 | GSE17721_LPS_VS_CPG_4H_BMDC_UP | MSigDB lists | GSE17721_LPS_VS_CPG_4H_BMDC_UP | 193 | 8 | 17377 | 282 |
DYRK1B,MXI1,ACSL1,RUNX2,RAB38,SAV1,DYNC1I1,PARP9 |
| 1.370e-02 | -4.29 | HER-positive_carcinoma | COSMIC cancer mutations | HER-positive_carcinoma | 2055 | 46 | 17385 | 281 |
ARHGAP26,ACVR1,BIK,RASL11B,KIF5C,PRKCA,ABHD4,RADIL,CBLN1,HMCN1,NUMBL,KMO,PMAIP1,MYC,PRKCD,RASD2,ACTA2,SGK1,TLN2,DNAH5,TSHR,PARP9,MN1,IL17RD,PXN,PDK1,PTPN6,OGDHL,MAFB,ABCC2,WNT11,ACVR2B,PRDM1,PLEKHA1,SGK2,SAV1,TLR6,TCF7L1,FGR,GNAO1,RASGRF2,MAP2K6,HK2,MAPK13,TNFRSF17,DDIT3 |
| 1.370e-02 | -4.29 | breast-carcinoma-HER-positive_carcinoma | COSMIC cancer mutations | breast-carcinoma-HER-positive_carcinoma | 2055 | 46 | 17385 | 281 |
ARHGAP26,ACVR1,BIK,RASL11B,KIF5C,PRKCA,ABHD4,RADIL,CBLN1,HMCN1,NUMBL,KMO,PMAIP1,MYC,PRKCD,RASD2,ACTA2,SGK1,TLN2,DNAH5,TSHR,PARP9,MN1,IL17RD,PXN,PDK1,PTPN6,OGDHL,MAFB,ABCC2,WNT11,ACVR2B,PRDM1,PLEKHA1,SGK2,SAV1,TLR6,TCF7L1,FGR,GNAO1,RASGRF2,MAP2K6,HK2,MAPK13,TNFRSF17,DDIT3 |
| 1.371e-02 | -4.29 | ACOT8 (acyl-CoA thioesterase 8) | protein interactions | 10005 | 11 | 2 | 17029 | 283 |
KLHL23,MYC |
| 1.371e-02 | -4.29 | CHAT (choline O-acetyltransferase) | protein interactions | 1103 | 11 | 2 | 17029 | 283 |
PRKCA,PRKCD |
| 1.371e-02 | -4.29 | DOC2A (double C2 domain alpha) | protein interactions | 8448 | 11 | 2 | 17029 | 283 |
STXBP1,UBASH3B |
| 1.371e-02 | -4.29 | MAGED4B (MAGE family member D4B) | protein interactions | 81557 | 11 | 2 | 17029 | 283 |
PJA1,SMYD3 |
| 1.371e-02 | -4.29 | FAM131C (family with sequence similarity 131 member C) | protein interactions | 348487 | 11 | 2 | 17029 | 283 |
HPCAL4,MYC |
| 1.371e-02 | -4.29 | GDPGP1 (GDP-D-glucose phosphorylase 1) | protein interactions | 390637 | 11 | 2 | 17029 | 283 |
LHPP,GAPDH |
| 1.371e-02 | -4.29 | INHBB (inhibin subunit beta B) | protein interactions | 3625 | 11 | 2 | 17029 | 283 |
ACVR2B,ACVR1 |
| 1.371e-02 | -4.29 | ITPKB (inositol-trisphosphate 3-kinase B) | protein interactions | 3707 | 11 | 2 | 17029 | 283 |
PDE4D,PRKCA |
| 1.373e-02 | -4.29 | GO_REGULATION_OF_TRANSFERASE_ACTIVITY | MSigDB lists | GO_REGULATION_OF_TRANSFERASE_ACTIVITY | 912 | 24 | 17377 | 282 |
ACSL1,DUSP8,UBASH3B,PTPN6,ADCY1,STRADB,CEBPA,WNT11,ACVR2B,GAS6,ARRDC4,TLR6,TRIB3,PPM1E,FGR,MAP2K6,ERN1,PRKCD,WWTR1,DAB2IP,TNFSF15,HSPA2,SMYD3,PKIA |
| 1.384e-02 | -4.28 | GO_CELL_SUBSTRATE_ADHESION | MSigDB lists | GO_CELL_SUBSTRATE_ADHESION | 156 | 7 | 17377 | 282 |
EPB41L5,GAS6,PXN,BVES,RADIL,JAM3,EPDR1 |
| 1.384e-02 | -4.28 | GSE37301_MULTIPOTENT_PROGENITOR_VS_CD4_TCELL_UP | MSigDB lists | GSE37301_MULTIPOTENT_PROGENITOR_VS_CD4_TCELL_UP | 156 | 7 | 17377 | 282 |
DLX2,PLEKHA1,PJA1,KLHL3,SATB1,FAM131C,PTPN6 |
| 1.384e-02 | -4.28 | GSE37301_PRO_BCELL_VS_CD4_TCELL_UP | MSigDB lists | GSE37301_PRO_BCELL_VS_CD4_TCELL_UP | 156 | 7 | 17377 | 282 |
DISP1,PLEKHA1,PDK1,TLR6,KLHL3,PFN2,EHD3 |
| 1.384e-02 | -4.28 | GSE17974_IL4_AND_ANTI_IL12_VS_UNTREATED_2H_ACT_CD4_TCELL_UP | MSigDB lists | GSE17974_IL4_AND_ANTI_IL12_VS_UNTREATED_2H_ACT_CD4_TCELL_UP | 156 | 7 | 17377 | 282 |
SLC40A1,IFT81,SATB1,DACT1,SLC39A8,MTUS1,GTF2F2 |
| 1.386e-02 | -4.28 | positive regulation of ion transport | biological process | GO:0043270 | 241 | 9 | 17256 | 270 |
SCN5A,KMO,WFS1,MAP2K6,PRKCD,EHD3,ABAT,STXBP1,HSPA2 |
| 1.386e-02 | -4.28 | positive regulation of protein modification by small protein conjugation or removal | biological process | GO:1903322 | 125 | 6 | 17256 | 270 |
INAVA,TRIB3,ARRDC4,FBXO4,WFS1,RASD2 |
| 1.394e-02 | -4.27 | INPP5E (inositol polyphosphate-5-phosphatase E) | protein interactions | 56623 | 56 | 4 | 17029 | 283 |
PHLDB2,RALGPS2,RASAL2,TANC2 |
| 1.400e-02 | -4.27 | human chr10q26.13 | chromosome location | human chr10q26.13 | 40 | 3 | 26185 | 331 |
LHPP,PLEKHA1,MIR4296 |
| 1.402e-02 | -4.27 | Follicle Stimulating Hormone (FSH) signaling pathway | WikiPathways | WP2035 | 27 | 3 | 5312 | 101 |
SGK1,BDNF,PRKCA |
| 1.408e-02 | -4.26 | PLASARI_TGFB1_TARGETS_10HR_UP | MSigDB lists | PLASARI_TGFB1_TARGETS_10HR_UP | 194 | 8 | 17377 | 282 |
RASL11B,RGS16,WNT11,PMAIP1,HSPA2,HK2,NUAK2,SPATA13 |
| 1.409e-02 | -4.26 | cation transmembrane transport | biological process | GO:0098655 | 602 | 17 | 17256 | 270 |
SLC40A1,SCN5A,SLC30A4,SLC9C1,SLC39A8,ATOX1,ATP6V1E2,SLC36A4,SLC25A28,ITPR2,GAS6,TMEM37,SLC2A13,CACNB4,ATP6AP1L,NCS1,DDIT3 |
| 1.410e-02 | -4.26 | astrocytoma_Grade_IV | COSMIC cancer mutations | astrocytoma_Grade_IV | 16366 | 273 | 17385 | 281 |
ARHGAP26,ACVR1,DUSP8,LGR4,RECK,LSM11,ALG1L,CEBPA,PRKCA,ABHD6,NCS1,EPDR1,PMAIP1,CFHR1,TMEM37,TSHR,TBC1D8,KLHL23,KLHL3,WISP3,EXOC6B,DSTN,BNIP3L,SLC25A28,ABCC2,TNS1,ACVR2B,SAV1,SPATA9,PLK2,RASGRF2,ALDOA,ARHGAP28,MAPK13,TMOD2,TANC2,SCN5A,ZHX3,CYP2J2,SLC36A4,TNFRSF10C,DYNC1I1,HPCAL4,NIPSNAP3B,MTUS1,IL17D,RALGPS2,MYC,ZIC5,SRGAP1,MOXD1,STXBP1,GPR161,EPB41L5,BDNF,QSOX1,SHISA2,ARRDC4,OR11H4,ZNF558,ADAMTS3,ISM1,LRRIQ3,QPCTL,EMILIN2,CLMN,IQSEC2,SMYD3,ZNF516,RASAL2,ST14,FAM131C,CCDC110,PLXNA2,COLEC10,TIAM2,TMEM53,ZNF827,KMO,DACT1,DAB2IP,PJA1,PDE4D,RAB27B,DNAH5,ATP6AP1L,KIAA1549,C3orf67,GAPDH,PDK1,SOX21,CYB5R2,SFXN4,ADCY1,NLGN4X,SATB2,WNT11,RAB38,TBC1D16,IQCK,WFS1,WWTR1,PLEKHG1,P4HA1,TNFSF15,DBP,KLHL31,COBL,KCTD1,C2orf88,CCDC148,MXI1,TMEM132C,BACE1,BIK,CCNJL,KIF5C,GAS6,ZNF219,NEO1,RGS17,GPR155,SMPDL3A,PARP9,TMC7,MN1,B9D1,SLC40A1,PXN,MPP1,GPR137C,GPLD1,TRIB3,FGR,GNAO1,MYOM2,TNFRSF17,DDIT3,B4GALT7,PHC1,CCDC126,ACSL1,HEBP1,PTPN21,NDRG2,NRN1,ABAT,ITPR2,SLC2A13,CACNB4,ABHD4,HMCN1,EPCAM,PPM1E,FKBP9,CPNE2,MARVELD2,DLX6,TMEM143,TLN2,FANK1,OR2W3,ZNF391,PGBD5,PNRC1,CAPN5,ATOX1,TTC22,PLEKHA1,SGK2,NT5DC2,PLEKHB1,DYRK1B,SPNS1,TCF7L1,ERN1,DLX2,APBA2,GPR63,LONRF1,RGS16,RUNX2,ZNF395,BVES,FBXO4,UBASH3B,CYP4V2,ATP6V1E2,RASL11B,SETBP1,CHADL,SATB1,PFN2,FHOD3,NUMBL,SLC30A4,GAN,EBF4,BNIP3,NCEH1,VGLL4,BARX1,IL17RD,SPATA13,EFNA3,MAFB,STRADB,WWC1,WDR25,PPFIA4,LHPP,PRDM1,B4GALNT3,KIAA0355,HK2,RNF122,DOCK1,RHPN2,FAM198B,KIF21B,RADIL,CBLN1,KCTD15,RPS6KL1,ZDHHC23,EEPD1,ZNF521,MAP7,MYH15,TMEM120B,HSPA2,FAM78B,PHLDB2,UROS,PTPN6,SLC39A8,JAM3,CENPV,IFT81,LMLN,ANKRD31,RBPMS2,DISP1,NECAB2,PRSS16,ARHGEF11,BLVRB,OVOL2,PRKCD,RASD2,EHD3,GTF2F2,ACTA2,PRICKLE2,TRIM3,SGK1,CCDC122,KIAA0408,MSX1,NUAK2,OGDHL,EXOG,PALLD,TLR6,CTIF,RERE,FMO4,MAP2K6,KIAA0513,ZNF474,THAP10,RNF157,PKIA |
| 1.410e-02 | -4.26 | REACTOME_SIGNALING_BY_FGFR_IN_DISEASE | MSigDB lists | REACTOME_SIGNALING_BY_FGFR_IN_DISEASE | 121 | 6 | 17377 | 282 |
IL17RD,TRIB3,ITPR2,PRKCA,PRKCD,ADCY1 |
| 1.421e-02 | -4.25 | Morphine addiction | KEGG pathways | hsa05032 | 91 | 5 | 7161 | 113 |
PDE4D,PRKCA,GRK3,GNAO1,ADCY1 |
| 1.421e-02 | -4.25 | Morphine addiction | KEGG pathways | ko05032 | 91 | 5 | 7161 | 113 |
PDE4D,PRKCA,GRK3,GNAO1,ADCY1 |
| 1.427e-02 | -4.25 | LIU_PROSTATE_CANCER_UP | MSigDB lists | LIU_PROSTATE_CANCER_UP | 88 | 5 | 17377 | 282 |
EPCAM,PPM1E,ST14,DNAH5,MAP2K6 |
| 1.427e-02 | -4.25 | CHEN_LIVER_METABOLISM_QTL_CIS | MSigDB lists | CHEN_LIVER_METABOLISM_QTL_CIS | 88 | 5 | 17377 | 282 |
TMEM37,KMO,CFHR1,FMO4,PLXNA2 |
| 1.427e-02 | -4.25 | WINTER_HYPOXIA_UP | MSigDB lists | WINTER_HYPOXIA_UP | 88 | 5 | 17377 | 282 |
P4HA1,BNIP3,GAPDH,TANC2,ALDOA |
| 1.429e-02 | -4.25 | GSE32901_NAIVE_VS_TH1_CD4_TCELL_DN | MSigDB lists | GSE32901_NAIVE_VS_TH1_CD4_TCELL_DN | 157 | 7 | 17377 | 282 |
B9D1,RALGPS2,PMAIP1,PLK2,PTPN6,MYC,GPLD1 |
| 1.432e-02 | -4.25 | GO_REGULATION_OF_TRANSPORT | MSigDB lists | GO_REGULATION_OF_TRANSPORT | 1733 | 40 | 17377 | 282 |
SCN5A,MXI1,LGR4,BVES,C4A,UBASH3B,ARL2,ITPR2,GAS6,ABAT,PRKCA,CACNB4,PFN2,NCS1,PMAIP1,DACT1,PRKCD,SGK1,DAB2IP,TMEM37,PDE4D,RAB27B,STXBP1,HSPA2,TBC1D8,PTPN6,BNIP3L,WWC1,SGK2,TLR6,TBC1D16,GPLD1,TRIB3,FGR,GNAO1,WFS1,MAP2K6,WWTR1,HK2,PKIA |
| 1.437e-02 | -4.24 | protein stabilization | biological process | GO:0050821 | 163 | 7 | 17256 | 270 |
MSX1,GAPDH,SAV1,PFN2,STXBP1,WFS1,PRKCD |
| 1.437e-02 | -4.24 | negative regulation of binding | biological process | GO:0051100 | 163 | 7 | 17256 | 270 |
EPB41L5,ARHGAP28,MSX1,DACT1,CFHR1,PRKCD,DDIT3 |
| 1.437e-02 | -4.24 | oxidoreduction coenzyme metabolic process | biological process | GO:0006733 | 126 | 6 | 17256 | 270 |
GAPDH,KMO,ALDOA,PARP9,OGDHL,HK2 |
| 1.440e-02 | -4.24 | positive regulation of cell communication | biological process | GO:0010647 | 1745 | 39 | 17256 | 270 |
ACVR1,NECAB2,LGR4,BIK,GAS6,TNFRSF10C,ABAT,PRKCA,MYORG,NEO1,PMAIP1,KMO,DACT1,PRKCD,RASD2,INAVA,DAB2IP,BNIP3,EPHB6,STXBP1,PARP9,BDNF,MSX1,PTPN6,WWC1,WNT11,GAREM1,ACVR2B,TLR6,GPLD1,FGR,ADAMTS3,MAP2K6,PLK2,ERN1,TNFSF15,TMOD2,DISP1,DDIT3 |
| 1.445e-02 | -4.24 | V$DBP_Q6 | MSigDB lists | V$DBP_Q6 | 234 | 9 | 17377 | 282 |
MN1,MXI1,KIAA0355,SOX21,ZIC5,PLXNA2,DAB2IP,RERE,GPLD1 |
| 1.445e-02 | -4.24 | AAAYWAACM_V$HFH4_01 | MSigDB lists | AAAYWAACM_V$HFH4_01 | 234 | 9 | 17377 | 282 |
BDNF,RALGPS2,KLHL3,SLC39A8,SGK1,PRDM1,HMCN1,HSPA2,NEO1 |
| 1.449e-02 | -4.23 | GSE29949_MICROGLIA_VS_DC_BRAIN_UP | MSigDB lists | GSE29949_MICROGLIA_VS_DC_BRAIN_UP | 195 | 8 | 17377 | 282 |
WWC1,RGS16,EPHB6,ACSL1,WISP3,VGLL4,MYC,PTPN21 |
| 1.449e-02 | -4.23 | HALLMARK_P53_PATHWAY | MSigDB lists | HALLMARK_P53_PATHWAY | 195 | 8 | 17377 | 282 |
RGS16,TRIB3,ST14,PLK2,CEBPA,ABAT,ABHD4,DDIT3 |
| 1.449e-02 | -4.23 | GSE10325_LUPUS_CD4_TCELL_VS_LUPUS_MYELOID_DN | MSigDB lists | GSE10325_LUPUS_CD4_TCELL_VS_LUPUS_MYELOID_DN | 195 | 8 | 17377 | 282 |
ACSL1,MPP1,BLVRB,PRKCD,MAFB,CLMN,CEBPA,TBC1D8 |
| 1.449e-02 | -4.23 | FARMER_BREAST_CANCER_APOCRINE_VS_BASAL | MSigDB lists | FARMER_BREAST_CANCER_APOCRINE_VS_BASAL | 316 | 11 | 17377 | 282 |
QSOX1,ACSL1,PMAIP1,KMO,CYP2J2,MYC,BLVRB,P4HA1,GPR161,PLEKHB1,MTUS1 |
| 1.451e-02 | -4.23 | GO_NEGATIVE_REGULATION_OF_WOUND_HEALING | MSigDB lists | GO_NEGATIVE_REGULATION_OF_WOUND_HEALING | 58 | 4 | 17377 | 282 |
PHLDB2,ABAT,UBASH3B,PRKCD |
| 1.452e-02 | -4.23 | positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway | biological process | GO:1902237 | 12 | 2 | 17256 | 270 |
PMAIP1,DDIT3 |
| 1.453e-02 | -4.23 | tube development | biological process | GO:0035295 | 800 | 21 | 17256 | 270 |
EPB41L5,ACVR1,LGR4,ST14,KLHL3,PLXNA2,CEBPA,WNT11,PRDM1,ACVR2B,OVOL2,SAV1,PRKCA,JAM3,GPLD1,EPCAM,MYC,RBPMS2,DACT1,DAB2IP,COBL |
| 1.454e-02 | -4.23 | SCHAEFFER_PROSTATE_DEVELOPMENT_48HR_DN | MSigDB lists | SCHAEFFER_PROSTATE_DEVELOPMENT_48HR_DN | 402 | 13 | 17377 | 282 |
IL17D,DZANK1,TMEM132C,UBASH3B,ZNF521,DAB2IP,SHISA2,LHPP,COLEC10,PALLD,SMYD3,KCTD1,TIAM2 |
| 1.456e-02 | -4.23 | regulation of Ras protein signal transduction | biological process | GO:0046578 | 243 | 9 | 17256 | 270 |
RALGPS2,RASAL2,ARHGEF11,RASGRF2,PLEKHG1,SPATA13,DAB2IP,IQSEC2,TIAM2 |
| 1.462e-02 | -4.23 | bicellular tight junction assembly | biological process | GO:0070830 | 33 | 3 | 17256 | 270 |
ARL2,WNT11,MARVELD2 |
| 1.462e-02 | -4.23 | regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway | biological process | GO:1902235 | 33 | 3 | 17256 | 270 |
PMAIP1,WFS1,DDIT3 |
| 1.462e-02 | -4.23 | positive regulation of amine transport | biological process | GO:0051954 | 33 | 3 | 17256 | 270 |
ABAT,KMO,STXBP1 |
| 1.463e-02 | -4.22 | GSE37301_HEMATOPOIETIC_STEM_CELL_VS_CD4_TCELL_DN | MSigDB lists | GSE37301_HEMATOPOIETIC_STEM_CELL_VS_CD4_TCELL_DN | 122 | 6 | 17377 | 282 |
BDNF,CPNE2,LHPP,TBC1D16,MPP1,RERE |
| 1.466e-02 | -4.22 | cellular response to stimulus | biological process | GO:0051716 | 6466 | 119 | 17256 | 270 |
ARHGAP26,ZNF516,ACVR1,ACSL1,LGR4,RASAL2,DOCK1,HEBP1,PLXNA2,RHPN2,NDRG2,CEBPA,ITPR2,PRKCA,RADIL,TIAM2,NCS1,EPCAM,CPNE2,PPM1E,PMAIP1,KMO,DACT1,RPS6KL1,EEPD1,DAB2IP,EPHB6,PDE4D,RAB27B,TSHR,OR2W3,HSPA2,GAPDH,PDK1,UROS,WISP3,PTPN6,CAPN5,ADCY1,BNIP3L,SATB2,WNT11,ABCC2,ACVR2B,RAB38,PLEKHA1,SGK2,SAV1,JAM3,GRK3,PLEKHB1,SPNS1,TCF7L1,PLK2,RASGRF2,WFS1,ERN1,WWTR1,ARHGAP28,TNFSF15,MAPK13,DISP1,GPR63,RGS16,SCN5A,RUNX2,ARHGEF11,CYP2J2,UBASH3B,FBXO4,ATP6V1E2,RASL11B,SLX1B,GAS6,TNFRSF10C,ZNF219,HPCAL4,NEO1,NUMBL,RALGPS2,GPR155,MYC,RASD2,PRKCD,GTF2F2,SRGAP1,SGK1,INAVA,PRICKLE2,BNIP3,NCEH1,STXBP1,GPR161,PARP9,EPB41L5,B9D1,BDNF,SLC40A1,IL17RD,MSX1,PXN,MPP1,NUAK2,EFNA3,STRADB,WWC1,GAREM1,OR11H4,ARRDC4,TLR6,GPLD1,TRIB3,FGR,GNAO1,MAP2K6,HK2,TNFRSF17,SMYD3,DDIT3 |
| 1.474e-02 | -4.22 | cerebellum development | biological process | GO:0021549 | 92 | 5 | 17256 | 270 |
NLGN4X,SCN5A,ABAT,CBLN1,RERE |
| 1.474e-02 | -4.22 | columnar/cuboidal epithelial cell differentiation | biological process | GO:0002065 | 92 | 5 | 17256 | 270 |
B9D1,ENAM,WNT11,PRDM1,SAV1 |
| 1.477e-02 | -4.21 | CAGTATT,MIR-200B,MIR-200C,MIR-429 | MSigDB lists | CAGTATT,MIR-200B,MIR-200C,MIR-429 | 447 | 14 | 17377 | 282 |
PPM1E,KCTD15,SCAMP1,ADAMTS3,KLHL3,KIAA0355,RECK,DACT1,PLK2,PRDM1,TLN2,NCS1,PKIA,MTUS1 |
| 1.480e-02 | -4.21 | KRIGE_RESPONSE_TO_TOSEDOSTAT_24HR_UP | MSigDB lists | KRIGE_RESPONSE_TO_TOSEDOSTAT_24HR_UP | 677 | 19 | 17377 | 282 |
RGS16,ACSL1,RECK,BLVRB,BNIP3L,MAFB,SHISA2,ITPR2,PLEKHA1,KIF21B,ARRDC4,PRKCA,TRIB3,KIAA0355,PMAIP1,TMEM143,MAP7,PDE4D,NCEH1 |
| 1.482e-02 | -4.21 | RIGGI_EWING_SARCOMA_PROGENITOR_UP | MSigDB lists | RIGGI_EWING_SARCOMA_PROGENITOR_UP | 403 | 13 | 17377 | 282 |
TCF7L1,MSX1,ADAMTS3,KMO,SLC39A8,SPATA13,NLGN4X,MAFB,TNFSF15,MYOM2,TMEM37,ABHD6,HMCN1 |
| 1.482e-02 | -4.21 | GO_SODIUM_CHANNEL_REGULATOR_ACTIVITY | MSigDB lists | GO_SODIUM_CHANNEL_REGULATOR_ACTIVITY | 32 | 3 | 17377 | 282 |
SGK1,SGK2,GPLD1 |
| 1.482e-02 | -4.21 | animal organ development | biological process | GO:0048513 | 2986 | 61 | 17256 | 270 |
SCN5A,ZNF516,ACVR1,RUNX2,LGR4,ST14,BVES,BIK,PLXNA2,NDRG2,CEBPA,OVOL2,GAS6,ABAT,HERC6,SATB1,CBLN1,MYORG,FHOD3,KDM7A,EPCAM,NUMBL,DLX6,MYC,ACTA2,BNIP3,DAB2IP,MYH15,BARX1,B9D1,EPB41L5,ENAM,SLC40A1,MSX1,KLHL3,PTPN6,SOX21,ADCY1,NLGN4X,MAFB,SATB2,WNT11,PRDM1,ACVR2B,PLEKHA1,SAV1,PALLD,JAM3,GPLD1,RERE,DYRK1B,WFS1,RBPMS2,GNAO1,WWTR1,HK2,MYOM2,DLX2,DBP,DISP1,COBL |
| 1.482e-02 | -4.21 | central_nervous_system | COSMIC cancer mutations | central_nervous_system | 16807 | 278 | 17385 | 281 |
ARHGAP26,ACVR1,DUSP8,LGR4,RECK,LSM11,ALG1L,CEBPA,PRKCA,ABHD6,NCS1,EPDR1,PMAIP1,CFHR1,TMEM37,TSHR,TBC1D8,KLHL23,KLHL3,WISP3,EXOC6B,DSTN,BNIP3L,SLC25A28,ABCC2,TNS1,ACVR2B,SAV1,SPATA9,PLK2,RASGRF2,ALDOA,ARHGAP28,MAPK13,TMOD2,TANC2,SCN5A,TMEM63C,ZHX3,CYP2J2,SLC36A4,TNFRSF10C,DYNC1I1,HPCAL4,NIPSNAP3B,MTUS1,IL17D,RALGPS2,MYC,ZIC5,SRGAP1,MOXD1,STXBP1,GPR161,EPB41L5,BDNF,QSOX1,SHISA2,ARRDC4,OR11H4,ZNF558,ADAMTS3,ISM1,LRRIQ3,QPCTL,EMILIN2,CLMN,IQSEC2,SMYD3,ZNF516,RASAL2,ST14,C4A,FAM131C,CCDC110,PLXNA2,COLEC10,TIAM2,TMEM53,ZNF827,KMO,DACT1,DAB2IP,PJA1,PDE4D,RAB27B,DNAH5,ATP6AP1L,KIAA1549,C3orf67,DZANK1,GAPDH,PDK1,SOX21,CYB5R2,SFXN4,ADCY1,NLGN4X,SATB2,WNT11,RAB38,TBC1D16,IQCK,ZNF697,WFS1,WWTR1,PLEKHG1,P4HA1,TNFSF15,DBP,KLHL31,COBL,KCTD1,C2orf88,CCDC148,MXI1,TMEM132C,BACE1,BIK,CCNJL,KIF5C,ARL2,GAS6,ZNF219,NEO1,RGS17,GPR155,SMPDL3A,PARP9,TMC7,MN1,B9D1,SLC40A1,PXN,MPP1,GPR137C,GPLD1,TRIB3,FGR,GNAO1,MYOM2,TNFRSF17,DDIT3,B4GALT7,PHC1,CCDC126,ACSL1,HEBP1,PTPN21,NDRG2,NRN1,ABAT,ITPR2,SLC2A13,CACNB4,ABHD4,HMCN1,EPCAM,PPM1E,FKBP9,CPNE2,MARVELD2,DLX6,TMEM143,TLN2,FANK1,OR2W3,ZNF391,PGBD5,PNRC1,CAPN5,ATOX1,TTC22,PLEKHA1,SGK2,NT5DC2,PLEKHB1,DYRK1B,SPNS1,TCF7L1,ERN1,DLX2,APBA2,GPR63,LONRF1,RGS16,RUNX2,ZNF395,BVES,FBXO4,UBASH3B,CYP4V2,ATP6V1E2,RASL11B,SETBP1,CHADL,SATB1,PFN2,FHOD3,NUMBL,SLC30A4,GAN,EBF4,BNIP3,NCEH1,VGLL4,BARX1,IL17RD,SPATA13,EFNA3,MAFB,STRADB,WWC1,WDR25,PPFIA4,LHPP,PRDM1,B4GALNT3,KIAA0355,HK2,RNF122,DOCK1,RHPN2,FAM198B,KIF21B,RADIL,CBLN1,KCTD15,RPS6KL1,ZDHHC23,EEPD1,ZNF521,MAP7,MYH15,TMEM120B,HSPA2,FAM78B,PHLDB2,UROS,SLC39A8,PTPN6,JAM3,CENPV,IFT81,LMLN,ANKRD31,RBPMS2,DISP1,NECAB2,PRSS16,ARHGEF11,BLVRB,OVOL2,PRKCD,RASD2,EHD3,GTF2F2,ACTA2,PRICKLE2,TRIM3,SGK1,CCDC122,KIAA0408,MSX1,NUAK2,OGDHL,EXOG,PALLD,TLR6,CTIF,RERE,FMO4,MAP2K6,KIAA0513,ZNF474,THAP10,RNF157,PKIA |
| 1.490e-02 | -4.21 | V$HNF3ALPHA_Q6 | MSigDB lists | V$HNF3ALPHA_Q6 | 196 | 8 | 17377 | 282 |
KCTD15,SLC39A8,GNAO1,SGK1,PDE4D,PRDM1,HMCN1,NEO1 |
| 1.500e-02 | -4.20 | GO_MUSCLE_SYSTEM_PROCESS | MSigDB lists | GO_MUSCLE_SYSTEM_PROCESS | 276 | 10 | 17377 | 282 |
SCN5A,PXN,ARHGEF11,MAP2K6,GNAO1,ALDOA,ACTA2,TMOD2,MYOM2,PDE4D |
| 1.501e-02 | -4.20 | human chr11p14.1 | chromosome location | human chr11p14.1 | 15 | 2 | 26185 | 331 |
BDNF,LGR4 |
| 1.505e-02 | -4.20 | BDNFACTOR | prints domains | PR01912 | 1 | 1 | 4652 | 70 |
BDNF |
| 1.505e-02 | -4.20 | FMOXYGENASE4 | prints domains | PR01124 | 1 | 1 | 4652 | 70 |
FMO4 |
| 1.505e-02 | -4.20 | TNFACTORR17 | prints domains | PR01967 | 1 | 1 | 4652 | 70 |
TNFRSF17 |
| 1.505e-02 | -4.20 | TSHRECEPTOR | prints domains | PR01145 | 1 | 1 | 4652 | 70 |
TSHR |
| 1.505e-02 | -4.20 | WOLFRAMIN | prints domains | PR02061 | 1 | 1 | 4652 | 70 |
WFS1 |
| 1.505e-02 | -4.20 | EP450ICYP2J | prints domains | PR01688 | 1 | 1 | 4652 | 70 |
CYP2J2 |
| 1.505e-02 | -4.20 | WOLFFAMILY | prints domains | PR02060 | 1 | 1 | 4652 | 70 |
WFS1 |
| 1.505e-02 | -4.20 | NACHANNEL5 | prints domains | PR01666 | 1 | 1 | 4652 | 70 |
SCN5A |
| 1.505e-02 | -4.20 | BACE1 | prints domains | PR01816 | 1 | 1 | 4652 | 70 |
BACE1 |
| 1.505e-02 | -4.20 | PHPHLIPASED | prints domains | PR00718 | 1 | 1 | 4652 | 70 |
GPLD1 |
| 1.505e-02 | -4.20 | EPENDYMIN | prints domains | PR00317 | 1 | 1 | 4652 | 70 |
EPDR1 |
| 1.505e-02 | -4.20 | MAPK Signaling Pathway | WikiPathways | WP382 | 170 | 8 | 5312 | 101 |
BDNF,MAP2K6,MYC,RASGRF2,PRKCD,MAPK13,TMEM37,DDIT3 |
| 1.510e-02 | -4.19 | human chr2q31.1 | chromosome location | human chr2q31.1 | 75 | 4 | 26185 | 331 |
DLX2,PDK1,KLHL23,GPR155 |
| 1.512e-02 | -4.19 | Cilostazol Action Pathway | SMPDB pathways | SMP00263 | 1 | 1 | 992 | 15 |
PDE4D |
| 1.512e-02 | -4.19 | Dipyridamole (Antiplatelet) Action Pathway | SMPDB pathways | SMP00264 | 1 | 1 | 992 | 15 |
PDE4D |
| 1.516e-02 | -4.19 | TGFB_receptor | interpro domains | IPR000333 | 12 | 2 | 18492 | 296 |
ACVR2B,ACVR1 |
| 1.516e-02 | -4.19 | regulation of actin cytoskeleton organization | biological process | GO:0032956 | 330 | 11 | 17256 | 270 |
PHLDB2,PPM1E,PXN,DSTN,PRKCD,ARHGAP28,TMOD2,WNT11,PFN2,JAM3,FHOD3 |
| 1.518e-02 | -4.19 | FIGUEROA_AML_METHYLATION_CLUSTER_6_UP | MSigDB lists | FIGUEROA_AML_METHYLATION_CLUSTER_6_UP | 123 | 6 | 17377 | 282 |
MAP7,TANC2,PMAIP1,PFN2,CENPV,PHC1 |
| 1.519e-02 | -4.19 | peptidyl-serine modification | biological process | GO:0018209 | 204 | 8 | 17256 | 270 |
PLK2,PRKCD,ERN1,SGK1,MAPK13,GAS6,PRKCA,SGK2 |
| 1.519e-02 | -4.19 | positive regulation of response to stimulus | biological process | GO:0048584 | 2194 | 47 | 17256 | 270 |
ACVR1,NECAB2,LGR4,DOCK1,C4A,BIK,GAS6,TNFRSF10C,ABAT,COLEC10,PRKCA,MYORG,NEO1,IL17D,PMAIP1,DACT1,MYC,CFHR1,PRKCD,RASD2,INAVA,DAB2IP,BNIP3,PDE4D,EPHB6,STXBP1,PARP9,BDNF,MSX1,PTPN6,WWC1,WNT11,GAREM1,ACVR2B,PLEKHA1,TLR6,GPLD1,FGR,ADAMTS3,PLK2,MAP2K6,ERN1,TNFSF15,TMOD2,MAPK13,DISP1,DDIT3 |
| 1.520e-02 | -4.19 | MORF_PTPRB | MSigDB lists | MORF_PTPRB | 236 | 9 | 17377 | 282 |
PPM1E,PDE4D,RUNX2,TANC2,PRKCA,KLHL23,SMYD3,EXOC6B,GPLD1 |
| 1.522e-02 | -4.18 | urinary_tract-bladder-carcinoma-transitional_cell_carcinoma | COSMIC cancer mutations | urinary_tract-bladder-carcinoma-transitional_cell_carcinoma | 6194 | 118 | 17385 | 281 |
ARHGAP26,ZNF516,ACVR1,LGR4,RASAL2,ST14,RECK,HEBP1,CCDC110,PTPN21,RHPN2,NRN1,SLC2A13,ITPR2,KIF21B,RADIL,CBLN1,HMCN1,TIAM2,EPDR1,EPCAM,FKBP9,PPM1E,RPS6KL1,CFHR1,ZNF521,TMEM143,ZDHHC23,MYH15,TMEM37,TLN2,DNAH5,TSHR,ATP6AP1L,HSPA2,C3orf67,PHLDB2,GAPDH,WISP3,KLHL3,CAPN5,ADCY1,NLGN4X,SATB2,TTC22,TNS1,PLEKHA1,RAB38,ACVR2B,TBC1D16,SPNS1,IFT81,LMLN,RASGRF2,ALDOA,PLEKHG1,P4HA1,ARHGAP28,MAPK13,TMOD2,DISP1,DBP,APBA2,COBL,LONRF1,CCDC148,RUNX2,ZNF395,ZHX3,FBXO4,CYP2J2,CYP4V2,CCNJL,SETBP1,ATP6V1E2,PFN2,DYNC1I1,NEO1,NUMBL,SLC30A4,GPR155,ZIC5,SRGAP1,CCDC122,SGK1,BNIP3,MOXD1,STXBP1,SMPDL3A,EPB41L5,TMC7,MN1,BDNF,QSOX1,SLC40A1,EFNA3,MAFB,PRDM1,PALLD,OR11H4,EXOG,B4GALNT3,TLR6,ZNF558,RERE,TRIB3,FGR,KIAA0355,GNAO1,LRRIQ3,EMILIN2,QPCTL,HK2,MYOM2,TNFRSF17,IQSEC2,DDIT3,PHC1 |
| 1.522e-02 | -4.18 | GSE34205_RSV_VS_FLU_INF_INFANT_PBMC_UP | MSigDB lists | GSE34205_RSV_VS_FLU_INF_INFANT_PBMC_UP | 159 | 7 | 17377 | 282 |
STRADB,TNS1,MXI1,OR2W3,GPR161,BNIP3L,ZDHHC23 |
| 1.522e-02 | -4.18 | GSE27859_MACROPHAGE_VS_DC_UP | MSigDB lists | GSE27859_MACROPHAGE_VS_DC_UP | 159 | 7 | 17377 | 282 |
PRDM1,RAB38,ARRDC4,STXBP1,PLK2,LSM11,DSTN |
| 1.523e-02 | -4.18 | nucleotide phosphorylation | biological process | GO:0046939 | 61 | 4 | 17256 | 270 |
GAPDH,ALDOA,OGDHL,HK2 |
| 1.524e-02 | -4.18 | divalent inorganic cation transport | biological process | GO:0072511 | 287 | 10 | 17256 | 270 |
SLC40A1,SLC30A4,SLC39A8,ABCC2,ITPR2,TMEM37,GAS6,CACNB4,NCS1,DDIT3 |
| 1.527e-02 | -4.18 | cell-substrate adhesion | biological process | GO:0031589 | 165 | 7 | 17256 | 270 |
EPB41L5,GAS6,PXN,BVES,RADIL,JAM3,EPDR1 |
| 1.530e-02 | -4.18 | GO_EMBRYO_DEVELOPMENT | MSigDB lists | GO_EMBRYO_DEVELOPMENT | 872 | 23 | 17377 | 282 |
B9D1,EPB41L5,MSX1,ACVR1,RUNX2,ST14,RECK,PLXNA2,MAFB,SATB2,CEBPA,WNT11,PRDM1,ACVR2B,OVOL2,DLX6,DACT1,DLX2,DISP1,TANC2,APBA2,COBL,DDIT3 |
| 1.537e-02 | -4.18 | Toll-like receptor 2-Toll-like receptor 6 protein complex | cellular component | GO:0035355 | 1 | 1 | 18223 | 280 |
TLR6 |
| 1.537e-02 | -4.18 | Ire1 complex | cellular component | GO:1990332 | 1 | 1 | 18223 | 280 |
ERN1 |
| 1.537e-02 | -4.18 | Golgi-associated vesicle lumen | cellular component | GO:0070931 | 1 | 1 | 18223 | 280 |
BACE1 |
| 1.537e-02 | -4.18 | 4-aminobutyrate transaminase complex | cellular component | GO:0032144 | 1 | 1 | 18223 | 280 |
ABAT |
| 1.537e-02 | -4.18 | parallel fiber | cellular component | GO:1990032 | 1 | 1 | 18223 | 280 |
DAB2IP |
| 1.537e-02 | -4.18 | GO_NEGATIVE_REGULATION_OF_SYNAPTIC_TRANSMISSION | MSigDB lists | GO_NEGATIVE_REGULATION_OF_SYNAPTIC_TRANSMISSION | 59 | 4 | 17377 | 282 |
NLGN4X,STXBP1,ABHD6,PLK2 |
| 1.537e-02 | -4.18 | GO_POSITIVE_REGULATION_OF_CYCLASE_ACTIVITY | MSigDB lists | GO_POSITIVE_REGULATION_OF_CYCLASE_ACTIVITY | 59 | 4 | 17377 | 282 |
PRKCA,TSHR,WFS1,ADCY1 |
| 1.537e-02 | -4.18 | LEE_LIVER_CANCER_MYC_DN | MSigDB lists | LEE_LIVER_CANCER_MYC_DN | 59 | 4 | 17377 | 282 |
RGS16,SATB1,CFHR1,TBC1D8 |
| 1.537e-02 | -4.18 | ZHAN_MULTIPLE_MYELOMA_CD1_VS_CD2_UP | MSigDB lists | ZHAN_MULTIPLE_MYELOMA_CD1_VS_CD2_UP | 59 | 4 | 17377 | 282 |
GPR63,TRIB3,KIF21B,TBC1D16 |
| 1.537e-02 | -4.18 | GO_POSITIVE_REGULATION_OF_LYASE_ACTIVITY | MSigDB lists | GO_POSITIVE_REGULATION_OF_LYASE_ACTIVITY | 59 | 4 | 17377 | 282 |
PRKCA,TSHR,WFS1,ADCY1 |
| 1.538e-02 | -4.17 | transitional_cell_carcinoma | COSMIC cancer mutations | transitional_cell_carcinoma | 6196 | 118 | 17385 | 281 |
ARHGAP26,ZNF516,ACVR1,LGR4,RASAL2,ST14,RECK,HEBP1,CCDC110,PTPN21,RHPN2,NRN1,SLC2A13,ITPR2,KIF21B,RADIL,CBLN1,HMCN1,TIAM2,EPDR1,EPCAM,FKBP9,PPM1E,RPS6KL1,CFHR1,ZNF521,TMEM143,ZDHHC23,MYH15,TMEM37,TLN2,DNAH5,TSHR,ATP6AP1L,HSPA2,C3orf67,PHLDB2,GAPDH,WISP3,KLHL3,CAPN5,ADCY1,NLGN4X,SATB2,TTC22,TNS1,PLEKHA1,RAB38,ACVR2B,TBC1D16,SPNS1,IFT81,LMLN,RASGRF2,ALDOA,PLEKHG1,P4HA1,ARHGAP28,MAPK13,TMOD2,DISP1,DBP,APBA2,COBL,LONRF1,CCDC148,RUNX2,ZNF395,ZHX3,FBXO4,CYP2J2,CYP4V2,CCNJL,SETBP1,ATP6V1E2,PFN2,DYNC1I1,NEO1,NUMBL,SLC30A4,GPR155,ZIC5,SRGAP1,CCDC122,SGK1,BNIP3,MOXD1,STXBP1,SMPDL3A,EPB41L5,TMC7,MN1,BDNF,QSOX1,SLC40A1,EFNA3,MAFB,PRDM1,PALLD,OR11H4,EXOG,B4GALNT3,TLR6,ZNF558,RERE,TRIB3,FGR,KIAA0355,GNAO1,LRRIQ3,EMILIN2,QPCTL,HK2,MYOM2,TNFRSF17,IQSEC2,DDIT3,PHC1 |
| 1.540e-02 | -4.17 | activin binding | molecular function | GO:0048185 | 12 | 2 | 17224 | 278 |
ACVR2B,ACVR1 |
| 1.548e-02 | -4.17 | cation transport | biological process | GO:0006812 | 805 | 21 | 17256 | 270 |
SLC40A1,SCN5A,TMEM63C,KLHL3,SLC9C1,SLC39A8,ATOX1,ATP6V1E2,SLC36A4,ABCC2,SLC25A28,ITPR2,GAS6,SLC2A13,CACNB4,NCS1,SLC30A4,SGK1,TMEM37,ATP6AP1L,DDIT3 |
| 1.553e-02 | -4.16 | epithelium development | biological process | GO:0060429 | 1060 | 26 | 17256 | 270 |
EPB41L5,B9D1,SLC40A1,ENAM,MSX1,ACVR1,LGR4,KLHL3,ST14,SOX21,PLXNA2,WNT11,PRDM1,ACVR2B,OVOL2,SAV1,PALLD,EPCAM,DACT1,MYC,MARVELD2,DLX6,ACTA2,PDE4D,COBL,BARX1 |
| 1.556e-02 | -4.16 | GO_ACTIVIN_BINDING | MSigDB lists | GO_ACTIVIN_BINDING | 12 | 2 | 17377 | 282 |
ACVR2B,ACVR1 |
| 1.556e-02 | -4.16 | GO_LATERAL_VENTRICLE_DEVELOPMENT | MSigDB lists | GO_LATERAL_VENTRICLE_DEVELOPMENT | 12 | 2 | 17377 | 282 |
NUMBL,DNAH5 |
| 1.556e-02 | -4.16 | GO_CELL_MIGRATION_INVOLVED_IN_GASTRULATION | MSigDB lists | GO_CELL_MIGRATION_INVOLVED_IN_GASTRULATION | 12 | 2 | 17377 | 282 |
EPB41L5,WNT11 |
| 1.556e-02 | -4.16 | GO_RENAL_ABSORPTION | MSigDB lists | GO_RENAL_ABSORPTION | 12 | 2 | 17377 | 282 |
SGK1,KLHL3 |
| 1.556e-02 | -4.16 | GO_POSITIVE_REGULATION_OF_ENDOPLASMIC_RETICULUM_UNFOLDED_PROTEIN_RESPONSE | MSigDB lists | GO_POSITIVE_REGULATION_OF_ENDOPLASMIC_RETICULUM_UNFOLDED_PROTEIN_RESPONSE | 12 | 2 | 17377 | 282 |
DAB2IP,ERN1 |
| 1.556e-02 | -4.16 | MODULE_272 | MSigDB lists | MODULE_272 | 12 | 2 | 17377 | 282 |
BLVRB,ALDOA |
| 1.556e-02 | -4.16 | GO_FOREBRAIN_NEURON_FATE_COMMITMENT | MSigDB lists | GO_FOREBRAIN_NEURON_FATE_COMMITMENT | 12 | 2 | 17377 | 282 |
SATB2,DLX2 |
| 1.556e-02 | -4.16 | PARK_OSTEOBLAST_DIFFERENTIATION_BY_PHENYLAMIL_UP | MSigDB lists | PARK_OSTEOBLAST_DIFFERENTIATION_BY_PHENYLAMIL_UP | 12 | 2 | 17377 | 282 |
TRIB3,ISM1 |
| 1.558e-02 | -4.16 | germ_cell_tumour | COSMIC cancer mutations | germ_cell_tumour | 877 | 23 | 17385 | 281 |
ACVR1,PDK1,NUAK2,PLXNA2,RHPN2,STRADB,CEBPA,ACVR2B,SGK2,PRKCA,TBC1D16,DYRK1B,PPM1E,TRIB3,FGR,PLK2,RPS6KL1,MAP2K6,PRKCD,ERN1,PRICKLE2,SGK1,MAPK13 |
| 1.559e-02 | -4.16 | REACTOME_DOWNSTREAM_SIGNAL_TRANSDUCTION | MSigDB lists | REACTOME_DOWNSTREAM_SIGNAL_TRANSDUCTION | 90 | 5 | 17377 | 282 |
TRIB3,ITPR2,PRKCA,PRKCD,ADCY1 |
| 1.563e-02 | -4.16 | serous_carcinoma | COSMIC cancer mutations | serous_carcinoma | 11298 | 200 | 17385 | 281 |
ARHGAP26,CCDC126,ACSL1,ACVR1,LGR4,RECK,PTPN21,ALG1L,SLC2A13,ITPR2,PRKCA,CACNB4,ABHD6,HMCN1,NCS1,EPDR1,CPNE2,FKBP9,PPM1E,DLX6,MARVELD2,CFHR1,TMEM37,TLN2,OR2W3,TSHR,FANK1,TBC1D8,PGBD5,KLHL3,DSTN,CAPN5,ABCC2,TNS1,PLEKHA1,ACVR2B,SGK2,PLEKHB1,DYRK1B,TCF7L1,PLK2,RASGRF2,ERN1,ALDOA,ARHGAP28,MAPK13,TMOD2,DLX2,TANC2,APBA2,LONRF1,GPR63,SCN5A,TMEM63C,RGS16,RUNX2,UBASH3B,CYP2J2,SETBP1,RASL11B,ATP6V1E2,CHADL,SLC36A4,PFN2,SATB1,DYNC1I1,FHOD3,MTUS1,NUMBL,RALGPS2,MYC,ZIC5,EBF4,SRGAP1,GAN,NCEH1,MOXD1,VGLL4,STXBP1,GPR161,EPB41L5,IL17RD,QSOX1,SPATA13,PPFIA4,WWC1,STRADB,SHISA2,PRDM1,OR11H4,B4GALNT3,ZNF558,ADAMTS3,KIAA0355,LRRIQ3,EMILIN2,HK2,CLMN,IQSEC2,RNF122,ZNF516,RASAL2,DOCK1,ST14,C4A,PLXNA2,RHPN2,COLEC10,KIF21B,CBLN1,TIAM2,TMEM53,ZNF827,KCTD15,KMO,RPS6KL1,DACT1,ZNF521,EEPD1,ZDHHC23,DAB2IP,MYH15,PJA1,PDE4D,DNAH5,TMEM120B,FAM78B,ATP6AP1L,HSPA2,PHLDB2,GAPDH,UROS,PDK1,SFXN4,ADCY1,NLGN4X,SATB2,WNT11,TBC1D16,JAM3,IQCK,IFT81,LMLN,ZNF697,WFS1,WWTR1,PLEKHG1,P4HA1,DISP1,KLHL31,COBL,KCTD1,CCDC148,NECAB2,PRSS16,ARHGEF11,BACE1,BIK,GAS6,OVOL2,ZNF219,NEO1,GPR155,PRKCD,RASD2,EHD3,GTF2F2,PRICKLE2,TRIM3,SGK1,KIAA0408,SMPDL3A,PARP9,TMC7,MN1,SLC40A1,MSX1,PXN,MPP1,OGDHL,NUAK2,EXOG,PALLD,TLR6,GPR137C,RERE,GPLD1,CTIF,TRIB3,FGR,FMO4,MAP2K6,KIAA0513,MYOM2,THAP10,RNF157,PKIA,DDIT3,B4GALT7,PHC1 |
| 1.565e-02 | -4.16 | regulation of oligodendrocyte apoptotic process | biological process | GO:1900141 | 1 | 1 | 17256 | 270 |
GAS6 |
| 1.565e-02 | -4.16 | regulation of phospholipid scramblase activity | biological process | GO:1900161 | 1 | 1 | 17256 | 270 |
PRKCD |
| 1.565e-02 | -4.16 | positive regulation of vesicle docking | biological process | GO:0106022 | 1 | 1 | 17256 | 270 |
STXBP1 |
| 1.565e-02 | -4.16 | iron cation export | biological process | GO:1903414 | 1 | 1 | 17256 | 270 |
SLC40A1 |
| 1.565e-02 | -4.16 | regulation of beta-catenin-TCF complex assembly | biological process | GO:1904863 | 1 | 1 | 17256 | 270 |
DACT1 |
| 1.565e-02 | -4.16 | regulation of glucosylceramide catabolic process | biological process | GO:2000752 | 1 | 1 | 17256 | 270 |
PRKCD |
| 1.565e-02 | -4.16 | positive regulation of sphingomyelin catabolic process | biological process | GO:2000755 | 1 | 1 | 17256 | 270 |
PRKCD |
| 1.565e-02 | -4.16 | benzylpenicillin metabolic process | biological process | GO:1901086 | 1 | 1 | 17256 | 270 |
ABCC2 |
| 1.565e-02 | -4.16 | positive regulation of glucosylceramide catabolic process | biological process | GO:2000753 | 1 | 1 | 17256 | 270 |
PRKCD |
| 1.565e-02 | -4.16 | negative regulation of beta-catenin-TCF complex assembly | biological process | GO:1904864 | 1 | 1 | 17256 | 270 |
DACT1 |
| 1.565e-02 | -4.16 | negative regulation of GTP binding | biological process | GO:1904425 | 1 | 1 | 17256 | 270 |
ARHGAP28 |
| 1.565e-02 | -4.16 | signal maturation | biological process | GO:0035638 | 1 | 1 | 17256 | 270 |
DISP1 |
| 1.565e-02 | -4.16 | spleen trabecula formation | biological process | GO:0060345 | 1 | 1 | 17256 | 270 |
SLC40A1 |
| 1.565e-02 | -4.16 | L-tryptophan transmembrane transport | biological process | GO:1904556 | 1 | 1 | 17256 | 270 |
SLC36A4 |
| 1.565e-02 | -4.16 | proline import across plasma membrane | biological process | GO:1905647 | 1 | 1 | 17256 | 270 |
SLC36A4 |
| 1.565e-02 | -4.16 | positive regulation of phospholipid scramblase activity | biological process | GO:1900163 | 1 | 1 | 17256 | 270 |
PRKCD |
| 1.565e-02 | -4.16 | intestinal stem cell homeostasis | biological process | GO:0036335 | 1 | 1 | 17256 | 270 |
LGR4 |
| 1.565e-02 | -4.16 | regulation of actin cytoskeleton organization by cell-cell adhesion | biological process | GO:0090138 | 1 | 1 | 17256 | 270 |
JAM3 |
| 1.565e-02 | -4.16 | toll-like receptor 6 signaling pathway | biological process | GO:0034150 | 1 | 1 | 17256 | 270 |
TLR6 |
| 1.565e-02 | -4.16 | response to triglyceride | biological process | GO:0034014 | 1 | 1 | 17256 | 270 |
GPLD1 |
| 1.565e-02 | -4.16 | endocardial cell fate commitment | biological process | GO:0060957 | 1 | 1 | 17256 | 270 |
ACVR1 |
| 1.565e-02 | -4.16 | L-proline transmembrane transport | biological process | GO:1904555 | 1 | 1 | 17256 | 270 |
SLC36A4 |
| 1.565e-02 | -4.16 | sebum secreting cell proliferation | biological process | GO:1990654 | 1 | 1 | 17256 | 270 |
PRDM1 |
| 1.565e-02 | -4.16 | mRNA splicing, via endonucleolytic cleavage and ligation | biological process | GO:0070054 | 1 | 1 | 17256 | 270 |
ERN1 |
| 1.565e-02 | -4.16 | dendritic transport of messenger ribonucleoprotein complex | biological process | GO:0098963 | 1 | 1 | 17256 | 270 |
KIF5C |
| 1.565e-02 | -4.16 | cellular response to thyrotropin-releasing hormone | biological process | GO:1905229 | 1 | 1 | 17256 | 270 |
TSHR |
| 1.565e-02 | -4.16 | GPI anchor release | biological process | GO:0006507 | 1 | 1 | 17256 | 270 |
GPLD1 |
| 1.565e-02 | -4.16 | peptidyl-serine trans-autophosphorylation | biological process | GO:1990579 | 1 | 1 | 17256 | 270 |
ERN1 |
| 1.565e-02 | -4.16 | intrinsic apoptotic signaling pathway in response to hypoxia | biological process | GO:1990144 | 1 | 1 | 17256 | 270 |
BNIP3 |
| 1.565e-02 | -4.16 | dendritic transport of ribonucleoprotein complex | biological process | GO:0098961 | 1 | 1 | 17256 | 270 |
KIF5C |
| 1.565e-02 | -4.16 | adenylate cyclase-activating adrenergic receptor signaling pathway involved in positive regulation of heart rate | biological process | GO:0086024 | 1 | 1 | 17256 | 270 |
PDE4D |
| 1.565e-02 | -4.16 | anterograde dendritic transport of messenger ribonucleoprotein complex | biological process | GO:0098964 | 1 | 1 | 17256 | 270 |
KIF5C |
| 1.565e-02 | -4.16 | negative regulation of gamma-aminobutyric acid secretion | biological process | GO:0014053 | 1 | 1 | 17256 | 270 |
ABAT |
| 1.565e-02 | -4.16 | rhombomere 6 development | biological process | GO:0021572 | 1 | 1 | 17256 | 270 |
MAFB |
| 1.565e-02 | -4.16 | ameloblast differentiation | biological process | GO:0036305 | 1 | 1 | 17256 | 270 |
ENAM |
| 1.565e-02 | -4.16 | positive regulation of aspartate secretion | biological process | GO:1904450 | 1 | 1 | 17256 | 270 |
ABAT |
| 1.565e-02 | -4.16 | negative regulation of oligodendrocyte apoptotic process | biological process | GO:1900142 | 1 | 1 | 17256 | 270 |
GAS6 |
| 1.565e-02 | -4.16 | positive regulation of metanephric cap mesenchymal cell proliferation | biological process | GO:0090096 | 1 | 1 | 17256 | 270 |
MYC |
| 1.565e-02 | -4.16 | L-proline import across plasma membrane | biological process | GO:1904271 | 1 | 1 | 17256 | 270 |
SLC36A4 |
| 1.565e-02 | -4.16 | positive regulation of brain-derived neurotrophic factor receptor signaling pathway | biological process | GO:0031550 | 1 | 1 | 17256 | 270 |
BDNF |
| 1.565e-02 | -4.16 | penicillin metabolic process | biological process | GO:0042316 | 1 | 1 | 17256 | 270 |
ABCC2 |
| 1.565e-02 | -4.16 | mercury ion transport | biological process | GO:0015694 | 1 | 1 | 17256 | 270 |
ABCC2 |
| 1.565e-02 | -4.16 | endocardial cushion cell fate commitment | biological process | GO:0061445 | 1 | 1 | 17256 | 270 |
ACVR1 |
| 1.565e-02 | -4.16 | negative regulation of renal albumin absorption | biological process | GO:2000533 | 1 | 1 | 17256 | 270 |
GAS6 |
| 1.565e-02 | -4.16 | regulation of metanephric cap mesenchymal cell proliferation | biological process | GO:0090095 | 1 | 1 | 17256 | 270 |
MYC |
| 1.565e-02 | -4.16 | intrinsic apoptotic signaling pathway in response to nitrosative stress | biological process | GO:1990442 | 1 | 1 | 17256 | 270 |
DDIT3 |
| 1.565e-02 | -4.16 | bilirubin transport | biological process | GO:0015723 | 1 | 1 | 17256 | 270 |
ABCC2 |
| 1.565e-02 | -4.16 | regulation of sphingomyelin catabolic process | biological process | GO:2000754 | 1 | 1 | 17256 | 270 |
PRKCD |
| 1.565e-02 | -4.16 | regulation of aspartate secretion | biological process | GO:1904448 | 1 | 1 | 17256 | 270 |
ABAT |
| 1.565e-02 | -4.16 | cellular response to anisomycin | biological process | GO:0072740 | 1 | 1 | 17256 | 270 |
MAPK13 |
| 1.565e-02 | -4.16 | patched ligand maturation | biological process | GO:0007225 | 1 | 1 | 17256 | 270 |
DISP1 |
| 1.565e-02 | -4.16 | beta-lactam antibiotic metabolic process | biological process | GO:0030653 | 1 | 1 | 17256 | 270 |
ABCC2 |
| 1.565e-02 | -4.16 | mRNA splicing via endonucleolytic cleavage and ligation involved in unfolded protein response | biological process | GO:0030969 | 1 | 1 | 17256 | 270 |
ERN1 |
| 1.565e-02 | -4.16 | ferrous iron export across plasma membrane | biological process | GO:1903988 | 1 | 1 | 17256 | 270 |
SLC40A1 |
| 1.565e-02 | -4.16 | cellular response to glycoprotein | biological process | GO:1904588 | 1 | 1 | 17256 | 270 |
TSHR |
| 1.565e-02 | -4.16 | cellular response to triglyceride | biological process | GO:0071401 | 1 | 1 | 17256 | 270 |
GPLD1 |
| 1.565e-02 | -4.16 | mRNA endonucleolytic cleavage involved in unfolded protein response | biological process | GO:0070055 | 1 | 1 | 17256 | 270 |
ERN1 |
| 1.565e-02 | -4.16 | protein trans-autophosphorylation | biological process | GO:0036290 | 1 | 1 | 17256 | 270 |
ERN1 |
| 1.566e-02 | -4.16 | Signaling by PTK6 | REACTOME pathways | R-HSA-8848021 | 67 | 4 | 10287 | 148 |
DAB2IP,PXN,RASAL2,DOCK1 |
| 1.570e-02 | -4.15 | DCAF8 (DDB1 and CUL4 associated factor 8) | protein interactions | 50717 | 58 | 4 | 17029 | 283 |
EPB41L5,INAVA,MYC,PTPN21 |
| 1.571e-02 | -4.15 | AMUNDSON_POOR_SURVIVAL_AFTER_GAMMA_RADIATION_2G | MSigDB lists | AMUNDSON_POOR_SURVIVAL_AFTER_GAMMA_RADIATION_2G | 160 | 7 | 17377 | 282 |
FKBP9,KIF21B,DOCK1,PFN2,PLK2,MYC,WWTR1 |
| 1.575e-02 | -4.15 | HALLMARK_ESTROGEN_RESPONSE_EARLY | MSigDB lists | HALLMARK_ESTROGEN_RESPONSE_EARLY | 198 | 8 | 17377 | 282 |
WWC1,ABAT,OVOL2,PMAIP1,MYC,WFS1,BLVRB,ADCY1 |
| 1.577e-02 | -4.15 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen | molecular function | GO:0016705 | 161 | 7 | 17224 | 278 |
KDM7A,P4HA1,MOXD1,KMO,FMO4,CYP2J2,CYP4V2 |
| 1.578e-02 | -4.15 | ARHGEF1 (Rho guanine nucleotide exchange factor 1) | protein interactions | 9138 | 32 | 3 | 17029 | 283 |
CCNJL,PRKCA,GAN |
| 1.578e-02 | -4.15 | SUMO1P1 (SUMO1 pseudogene 1) | protein interactions | 391257 | 32 | 3 | 17029 | 283 |
SETBP1,SATB1,PHC1 |
| 1.584e-02 | -4.14 | GO_HOMEOSTATIC_PROCESS | MSigDB lists | GO_HOMEOSTATIC_PROCESS | 1276 | 31 | 17377 | 282 |
QSOX1,SLC40A1,LGR4,KLHL3,SFXN4,FBXO4,SLC39A8,ATOX1,ADCY1,ATP6V1E2,CEBPA,SLC25A28,SLX1B,ABCC2,ITPR2,GAS6,RAB38,SGK2,CACNB4,JAM3,NEO1,SLC30A4,PMAIP1,WFS1,MYC,ALDOA,ERN1,HK2,SGK1,TNFRSF17,DDIT3 |
| 1.589e-02 | -4.14 | Enamelin | pfam domains | PF15362 | 1 | 1 | 17054 | 271 |
ENAM |
| 1.589e-02 | -4.14 | BCMA-Tall_bind | pfam domains | PF09257 | 1 | 1 | 17054 | 271 |
TNFRSF17 |
| 1.589e-02 | -4.14 | DUF4772 | pfam domains | PF15997 | 1 | 1 | 17054 | 271 |
ZNF395 |
| 1.589e-02 | -4.14 | bcl-2I13 | pfam domains | PF12201 | 1 | 1 | 17054 | 271 |
BIK |
| 1.589e-02 | -4.14 | Peptidase_M8 | pfam domains | PF01457 | 1 | 1 | 17054 | 271 |
LMLN |
| 1.589e-02 | -4.14 | Zn_dep_PLPC | pfam domains | PF00882 | 1 | 1 | 17054 | 271 |
GPLD1 |
| 1.589e-02 | -4.14 | GIY-YIG | pfam domains | PF01541 | 1 | 1 | 17054 | 271 |
SLX1B |
| 1.589e-02 | -4.14 | DUF4538 | pfam domains | PF15061 | 1 | 1 | 17054 | 271 |
SMIM20 |
| 1.589e-02 | -4.14 | Mem_trans | pfam domains | PF03547 | 1 | 1 | 17054 | 271 |
GPR155 |
| 1.589e-02 | -4.14 | Ependymin | pfam domains | PF00811 | 1 | 1 | 17054 | 271 |
EPDR1 |
| 1.589e-02 | -4.14 | IL17R_D_N | pfam domains | PF16742 | 1 | 1 | 17054 | 271 |
IL17RD |
| 1.589e-02 | -4.14 | DUF4745 | pfam domains | PF15923 | 1 | 1 | 17054 | 271 |
KIAA0355 |
| 1.589e-02 | -4.14 | DUF3754 | pfam domains | PF12576 | 1 | 1 | 17054 | 271 |
TMEM143 |
| 1.589e-02 | -4.14 | DUF4677 | pfam domains | PF15726 | 1 | 1 | 17054 | 271 |
CCDC184 |
| 1.589e-02 | -4.14 | GFA | pfam domains | PF04828 | 1 | 1 | 17054 | 271 |
CENPV |
| 1.589e-02 | -4.14 | SmAKAP | pfam domains | PF15127 | 1 | 1 | 17054 | 271 |
C2orf88 |
| 1.589e-02 | -4.14 | DZR | pfam domains | PF12773 | 1 | 1 | 17054 | 271 |
DZANK1 |
| 1.589e-02 | -4.14 | Myc-LZ | pfam domains | PF02344 | 1 | 1 | 17054 | 271 |
MYC |
| 1.589e-02 | -4.14 | VGLL4 | pfam domains | PF15245 | 1 | 1 | 17054 | 271 |
VGLL4 |
| 1.589e-02 | -4.14 | HEM4 | pfam domains | PF02602 | 1 | 1 | 17054 | 271 |
UROS |
| 1.589e-02 | -4.14 | SPATA9 | pfam domains | PF15824 | 1 | 1 | 17054 | 271 |
SPATA9 |
| 1.589e-02 | -4.14 | TFIIF_beta | pfam domains | PF02270 | 1 | 1 | 17054 | 271 |
GTF2F2 |
| 1.589e-02 | -4.14 | FPN1 | pfam domains | PF06963 | 1 | 1 | 17054 | 271 |
SLC40A1 |
| 1.589e-02 | -4.14 | TMEM37 | pfam domains | PF15108 | 1 | 1 | 17054 | 271 |
TMEM37 |
| 1.589e-02 | -4.14 | TRIQK | pfam domains | PF15168 | 1 | 1 | 17054 | 271 |
TRIQK |
| 1.589e-02 | -4.14 | Fn3_assoc | pfam domains | PF13287 | 1 | 1 | 17054 | 271 |
DZANK1 |
| 1.589e-02 | -4.14 | DUF829 | pfam domains | PF05705 | 1 | 1 | 17054 | 271 |
TMEM53 |
| 1.589e-02 | -4.14 | PMAIP1 | pfam domains | PF15150 | 1 | 1 | 17054 | 271 |
PMAIP1 |
| 1.590e-02 | -4.14 | Signaling by EGFR | REACTOME pathways | R-HSA-177929 | 364 | 11 | 10287 | 148 |
IL17RD,TRIB3,PXN,RASAL2,DUSP8,RASGRF2,PRKCD,ADCY1,DAB2IP,ITPR2,PRKCA |
| 1.591e-02 | -4.14 | face | COSMIC cancer mutations | face | 2182 | 48 | 17385 | 281 |
ACSL1,ZHX3,BVES,ST14,ARHGEF11,CYP2J2,PTPN21,PLXNA2,SETBP1,RHPN2,ITPR2,KIF21B,DYNC1I1,RADIL,HMCN1,FHOD3,RGS17,RALGPS2,KMO,ZNF521,SRGAP1,KIAA0408,TLN2,DNAH5,C3orf67,TMC7,QSOX1,SLC39A8,SOX21,ADCY1,TNS1,ABCC2,WNT11,PRDM1,PALLD,ZNF558,RERE,SPNS1,ADAMTS3,RASGRF2,LRRIQ3,EMILIN2,HK2,CLMN,MYOM2,SMYD3,COBL,B4GALT7 |
| 1.593e-02 | -4.14 | striated_muscle | COSMIC cancer mutations | striated_muscle | 4319 | 86 | 17385 | 281 |
ARHGAP26,ACSL1,ZNF516,DOCK1,FAM131C,CEBPA,SLC2A13,COLEC10,RADIL,HMCN1,TIAM2,EPDR1,ZNF827,PPM1E,KMO,TMEM143,EEPD1,MYH15,TLN2,DNAH5,TSHR,TBC1D8,GAPDH,PNRC1,KLHL23,SLC39A8,PTPN6,CAPN5,NLGN4X,SATB2,WNT11,ABCC2,PLEKHA1,CENPV,DYRK1B,TCF7L1,PLK2,WFS1,RASGRF2,ERN1,PLEKHG1,MAPK13,DISP1,KLHL31,TANC2,APBA2,COBL,TMEM63C,SCN5A,TMEM132C,SCART1,ARHGEF11,ZHX3,CYP2J2,ARL2,PFN2,FHOD3,MTUS1,NEO1,NUMBL,GPR155,ZIC5,GAN,EBF4,PRICKLE2,KIAA0408,MOXD1,VGLL4,PARP9,MN1,IL17RD,EFNA3,SPATA13,OGDHL,WWC1,PRDM1,B4GALNT3,RERE,ADAMTS3,LRRIQ3,EMILIN2,HK2,MYOM2,ZNF474,TNFRSF17,PHC1 |
| 1.597e-02 | -4.14 | negative regulation of protein complex assembly | biological process | GO:0031333 | 129 | 6 | 17256 | 270 |
TMOD2,PFN2,STXBP1,DACT1,PRKCD,FHOD3 |
| 1.601e-02 | -4.13 | RasGRF2 | interpro domains | IPR030744 | 1 | 1 | 18492 | 296 |
RASGRF2 |
| 1.601e-02 | -4.13 | UBASH3B_SH3 | interpro domains | IPR035632 | 1 | 1 | 18492 | 296 |
UBASH3B |
| 1.601e-02 | -4.13 | Sav | interpro domains | IPR030030 | 1 | 1 | 18492 | 296 |
SAV1 |
| 1.601e-02 | -4.13 | MOXD1 | interpro domains | IPR028463 | 1 | 1 | 18492 | 296 |
MOXD1 |
| 1.601e-02 | -4.13 | Gprt_PLipase_D | interpro domains | IPR001028 | 1 | 1 | 18492 | 296 |
GPLD1 |
| 1.601e-02 | -4.13 | FHOD3 | interpro domains | IPR027651 | 1 | 1 | 18492 | 296 |
FHOD3 |
| 1.601e-02 | -4.13 | Noxa | interpro domains | IPR024140 | 1 | 1 | 18492 | 296 |
PMAIP1 |
| 1.601e-02 | -4.13 | DZR | interpro domains | IPR025874 | 1 | 1 | 18492 | 296 |
DZANK1 |
| 1.601e-02 | -4.13 | Fgr_SH2 | interpro domains | IPR035693 | 1 | 1 | 18492 | 296 |
FGR |
| 1.601e-02 | -4.13 | Lsm11_M | interpro domains | IPR034109 | 1 | 1 | 18492 | 296 |
LSM11 |
| 1.601e-02 | -4.13 | KLHL16 | interpro domains | IPR030579 | 1 | 1 | 18492 | 296 |
GAN |
| 1.601e-02 | -4.13 | C3orf67 | interpro domains | IPR030467 | 1 | 1 | 18492 | 296 |
C3orf67 |
| 1.601e-02 | -4.13 | Palladin_C | interpro domains | IPR033017 | 1 | 1 | 18492 | 296 |
PALLD |
| 1.601e-02 | -4.13 | TNFR_17 | interpro domains | IPR022320 | 1 | 1 | 18492 | 296 |
TNFRSF17 |
| 1.601e-02 | -4.13 | DUF4745 | interpro domains | IPR031813 | 1 | 1 | 18492 | 296 |
KIAA0355 |
| 1.601e-02 | -4.13 | Bcl2-int_killer | interpro domains | IPR024579 | 1 | 1 | 18492 | 296 |
BIK |
| 1.601e-02 | -4.13 | GRAF_SH3 | interpro domains | IPR035481 | 1 | 1 | 18492 | 296 |
ARHGAP26 |
| 1.601e-02 | -4.13 | PRG_PH | interpro domains | IPR037803 | 1 | 1 | 18492 | 296 |
ARHGEF11 |
| 1.601e-02 | -4.13 | RBPMS2_RRM | interpro domains | IPR034787 | 1 | 1 | 18492 | 296 |
RBPMS2 |
| 1.601e-02 | -4.13 | DYRK1B | interpro domains | IPR033565 | 1 | 1 | 18492 | 296 |
DYRK1B |
| 1.601e-02 | -4.13 | SFXN4 | interpro domains | IPR028825 | 1 | 1 | 18492 | 296 |
SFXN4 |
| 1.601e-02 | -4.13 | TBC1D8_PH-GRAM1 | interpro domains | IPR036009 | 1 | 1 | 18492 | 296 |
TBC1D8 |
| 1.601e-02 | -4.13 | FAM78B | interpro domains | IPR029639 | 1 | 1 | 18492 | 296 |
FAM78B |
| 1.601e-02 | -4.13 | Wolframin | interpro domains | IPR026208 | 1 | 1 | 18492 | 296 |
WFS1 |
| 1.601e-02 | -4.13 | Apba2 | interpro domains | IPR030529 | 1 | 1 | 18492 | 296 |
APBA2 |
| 1.601e-02 | -4.13 | TNFSF15 | interpro domains | IPR008064 | 1 | 1 | 18492 | 296 |
TNFSF15 |
| 1.601e-02 | -4.13 | DUF3754 | interpro domains | IPR022227 | 1 | 1 | 18492 | 296 |
TMEM143 |
| 1.601e-02 | -4.13 | Flavin_mOase_4 | interpro domains | IPR002256 | 1 | 1 | 18492 | 296 |
FMO4 |
| 1.601e-02 | -4.13 | MAP7 | interpro domains | IPR030707 | 1 | 1 | 18492 | 296 |
MAP7 |
| 1.601e-02 | -4.13 | BACE1 | interpro domains | IPR009120 | 1 | 1 | 18492 | 296 |
BACE1 |
| 1.601e-02 | -4.13 | Ependymin | interpro domains | IPR001299 | 1 | 1 | 18492 | 296 |
EPDR1 |
| 1.601e-02 | -4.13 | Neogenin | interpro domains | IPR033024 | 1 | 1 | 18492 | 296 |
NEO1 |
| 1.601e-02 | -4.13 | Enamelin | interpro domains | IPR015673 | 1 | 1 | 18492 | 296 |
ENAM |
| 1.601e-02 | -4.13 | Ferroportin-1 | interpro domains | IPR009716 | 1 | 1 | 18492 | 296 |
SLC40A1 |
| 1.601e-02 | -4.13 | DNA_damage_induc_transcript_3 | interpro domains | IPR016670 | 1 | 1 | 18492 | 296 |
DDIT3 |
| 1.601e-02 | -4.13 | MARVELD2 | interpro domains | IPR031177 | 1 | 1 | 18492 | 296 |
MARVELD2 |
| 1.601e-02 | -4.13 | PDZ-RhoGEF | interpro domains | IPR032919 | 1 | 1 | 18492 | 296 |
ARHGEF11 |
| 1.601e-02 | -4.13 | DAB2IP | interpro domains | IPR030403 | 1 | 1 | 18492 | 296 |
DAB2IP |
| 1.601e-02 | -4.13 | VGLL4 | interpro domains | IPR028184 | 1 | 1 | 18492 | 296 |
VGLL4 |
| 1.601e-02 | -4.13 | srGAP1_F-BAR | interpro domains | IPR037451 | 1 | 1 | 18492 | 296 |
SRGAP1 |
| 1.601e-02 | -4.13 | GPR155_DEP | interpro domains | IPR037368 | 1 | 1 | 18492 | 296 |
GPR155 |
| 1.601e-02 | -4.13 | PJA1 | interpro domains | IPR031227 | 1 | 1 | 18492 | 296 |
PJA1 |
| 1.601e-02 | -4.13 | VILIP-2 | interpro domains | IPR029534 | 1 | 1 | 18492 | 296 |
HPCAL4 |
| 1.601e-02 | -4.13 | Wolframin_fam | interpro domains | IPR026209 | 1 | 1 | 18492 | 296 |
WFS1 |
| 1.601e-02 | -4.13 | PLPC/GPLD1 | interpro domains | IPR029002 | 1 | 1 | 18492 | 296 |
GPLD1 |
| 1.601e-02 | -4.13 | DUF4677 | interpro domains | IPR031458 | 1 | 1 | 18492 | 296 |
CCDC184 |
| 1.601e-02 | -4.13 | N/H_exchanger_10 | interpro domains | IPR028483 | 1 | 1 | 18492 | 296 |
SLC9C1 |
| 1.601e-02 | -4.13 | 4NH2But_aminotransferase_euk | interpro domains | IPR004631 | 1 | 1 | 18492 | 296 |
ABAT |
| 1.601e-02 | -4.13 | TBC1D8_PH-GRAM2 | interpro domains | IPR036016 | 1 | 1 | 18492 | 296 |
TBC1D8 |
| 1.601e-02 | -4.13 | TSH_rcpt | interpro domains | IPR002274 | 1 | 1 | 18492 | 296 |
TSHR |
| 1.601e-02 | -4.13 | Small_membr_AKAP | interpro domains | IPR027969 | 1 | 1 | 18492 | 296 |
C2orf88 |
| 1.601e-02 | -4.13 | Hist-Lys_N-MeTrfase_Smyd3 | interpro domains | IPR025805 | 1 | 1 | 18492 | 296 |
SMYD3 |
| 1.601e-02 | -4.13 | RPS6KL1 | interpro domains | IPR035050 | 1 | 1 | 18492 | 296 |
RPS6KL1 |
| 1.601e-02 | -4.13 | Kynurenine_monooxygenase | interpro domains | IPR027545 | 1 | 1 | 18492 | 296 |
KMO |
| 1.601e-02 | -4.13 | MPP1_SH3 | interpro domains | IPR035475 | 1 | 1 | 18492 | 296 |
MPP1 |
| 1.601e-02 | -4.13 | Na_channel_a5su | interpro domains | IPR008053 | 1 | 1 | 18492 | 296 |
SCN5A |
| 1.601e-02 | -4.13 | GRAF_BAR | interpro domains | IPR035483 | 1 | 1 | 18492 | 296 |
ARHGAP26 |
| 1.601e-02 | -4.13 | Dstn | interpro domains | IPR029924 | 1 | 1 | 18492 | 296 |
DSTN |
| 1.601e-02 | -4.13 | PFN2 | interpro domains | IPR029891 | 1 | 1 | 18492 | 296 |
PFN2 |
| 1.601e-02 | -4.13 | 4pyrrol_syn_uPrphyn_synt_sf | interpro domains | IPR036108 | 1 | 1 | 18492 | 296 |
UROS |
| 1.601e-02 | -4.13 | Paxillin | interpro domains | IPR001904 | 1 | 1 | 18492 | 296 |
PXN |
| 1.601e-02 | -4.13 | DBP | interpro domains | IPR029830 | 1 | 1 | 18492 | 296 |
DBP |
| 1.601e-02 | -4.13 | nPKC_delta | interpro domains | IPR034667 | 1 | 1 | 18492 | 296 |
PRKCD |
| 1.601e-02 | -4.13 | Band4 | interpro domains | IPR030694 | 1 | 1 | 18492 | 296 |
EPB41L5 |
| 1.601e-02 | -4.13 | 4pyrrol_synth_uPrphyn_synth | interpro domains | IPR003754 | 1 | 1 | 18492 | 296 |
UROS |
| 1.601e-02 | -4.13 | LZTS3 | interpro domains | IPR033295 | 1 | 1 | 18492 | 296 |
LZTS3 |
| 1.601e-02 | -4.13 | PPFIA4 | interpro domains | IPR030439 | 1 | 1 | 18492 | 296 |
PPFIA4 |
| 1.601e-02 | -4.13 | IFT81 | interpro domains | IPR029600 | 1 | 1 | 18492 | 296 |
IFT81 |
| 1.601e-02 | -4.13 | GIY-YIG_endonuc_sf | interpro domains | IPR035901 | 1 | 1 | 18492 | 296 |
SLX1B |
| 1.601e-02 | -4.13 | CC191 | interpro domains | IPR026174 | 1 | 1 | 18492 | 296 |
CCDC191 |
| 1.601e-02 | -4.13 | MafB | interpro domains | IPR028571 | 1 | 1 | 18492 | 296 |
MAFB |
| 1.601e-02 | -4.13 | SPATA9 | interpro domains | IPR031659 | 1 | 1 | 18492 | 296 |
SPATA9 |
| 1.601e-02 | -4.13 | cPKC_alpha | interpro domains | IPR034663 | 1 | 1 | 18492 | 296 |
PRKCA |
| 1.601e-02 | -4.13 | MN1 | interpro domains | IPR037644 | 1 | 1 | 18492 | 296 |
MN1 |
| 1.601e-02 | -4.13 | Peptidase_S1A_matripase | interpro domains | IPR017051 | 1 | 1 | 18492 | 296 |
ST14 |
| 1.601e-02 | -4.13 | TRIQK | interpro domains | IPR024842 | 1 | 1 | 18492 | 296 |
TRIQK |
| 1.601e-02 | -4.13 | IL17R_D_N | interpro domains | IPR031951 | 1 | 1 | 18492 | 296 |
IL17RD |
| 1.601e-02 | -4.13 | Peptidase_M8 | interpro domains | IPR001577 | 1 | 1 | 18492 | 296 |
LMLN |
| 1.601e-02 | -4.13 | Competence_ComEA_HhH | interpro domains | IPR004509 | 1 | 1 | 18492 | 296 |
EEPD1 |
| 1.601e-02 | -4.13 | SMIM20 | interpro domains | IPR027917 | 1 | 1 | 18492 | 296 |
SMIM20 |
| 1.601e-02 | -4.13 | ABCC2 | interpro domains | IPR030247 | 1 | 1 | 18492 | 296 |
ABCC2 |
| 1.601e-02 | -4.13 | TMOD2 | interpro domains | IPR030130 | 1 | 1 | 18492 | 296 |
TMOD2 |
| 1.601e-02 | -4.13 | Slx1 | interpro domains | IPR027520 | 1 | 1 | 18492 | 296 |
SLX1B |
| 1.601e-02 | -4.13 | Ependymin_CS | interpro domains | IPR018224 | 1 | 1 | 18492 | 296 |
EPDR1 |
| 1.601e-02 | -4.13 | TFIIF_beta | interpro domains | IPR003196 | 1 | 1 | 18492 | 296 |
GTF2F2 |
| 1.601e-02 | -4.13 | Tmem37 | interpro domains | IPR029372 | 1 | 1 | 18492 | 296 |
TMEM37 |
| 1.601e-02 | -4.13 | PKC_delta | interpro domains | IPR027436 | 1 | 1 | 18492 | 296 |
PRKCD |
| 1.601e-02 | -4.13 | NDRG2 | interpro domains | IPR030690 | 1 | 1 | 18492 | 296 |
NDRG2 |
| 1.601e-02 | -4.13 | Wnt-11 | interpro domains | IPR026536 | 1 | 1 | 18492 | 296 |
WNT11 |
| 1.601e-02 | -4.13 | DOCK1 | interpro domains | IPR030717 | 1 | 1 | 18492 | 296 |
DOCK1 |
| 1.601e-02 | -4.13 | DUF829_TMEM53 | interpro domains | IPR008547 | 1 | 1 | 18492 | 296 |
TMEM53 |
| 1.601e-02 | -4.13 | Cyt_P450_E_grp-I_CYP2J-like | interpro domains | IPR008071 | 1 | 1 | 18492 | 296 |
CYP2J2 |
| 1.601e-02 | -4.13 | TLR6 | interpro domains | IPR027187 | 1 | 1 | 18492 | 296 |
TLR6 |
| 1.601e-02 | -4.13 | RalGPS1/2 | interpro domains | IPR030708 | 1 | 1 | 18492 | 296 |
RALGPS2 |
| 1.601e-02 | -4.13 | MTUS1 | interpro domains | IPR029786 | 1 | 1 | 18492 | 296 |
MTUS1 |
| 1.601e-02 | -4.13 | Fn3_assoc_repeat | interpro domains | IPR026876 | 1 | 1 | 18492 | 296 |
DZANK1 |
| 1.601e-02 | -4.13 | DUF4772 | interpro domains | IPR031940 | 1 | 1 | 18492 | 296 |
ZNF395 |
| 1.601e-02 | -4.13 | Dact1 | interpro domains | IPR024848 | 1 | 1 | 18492 | 296 |
DACT1 |
| 1.601e-02 | -4.13 | BCMA_Tall-1-bd | interpro domains | IPR015337 | 1 | 1 | 18492 | 296 |
TNFRSF17 |
| 1.601e-02 | -4.13 | PDZRhoGEF_RGS | interpro domains | IPR037889 | 1 | 1 | 18492 | 296 |
ARHGEF11 |
| 1.601e-02 | -4.13 | GFA/CENP-V | interpro domains | IPR006913 | 1 | 1 | 18492 | 296 |
CENPV |
| 1.601e-02 | -4.13 | GRAF | interpro domains | IPR030061 | 1 | 1 | 18492 | 296 |
ARHGAP26 |
| 1.601e-02 | -4.13 | Brain-der_neurotrophic_factor | interpro domains | IPR020430 | 1 | 1 | 18492 | 296 |
BDNF |
| 1.601e-02 | -4.13 | Myc-LZ | interpro domains | IPR003327 | 1 | 1 | 18492 | 296 |
MYC |
| 1.601e-02 | -4.13 | Mem_trans | interpro domains | IPR004776 | 1 | 1 | 18492 | 296 |
GPR155 |
| 1.601e-02 | -4.13 | Tribbles_TRB3 | interpro domains | IPR024106 | 1 | 1 | 18492 | 296 |
TRIB3 |
| 1.603e-02 | -4.13 | BACK | pfam domains | PF07707 | 61 | 4 | 17054 | 271 |
KLHL31,KLHL23,KLHL3,GAN |
| 1.609e-02 | -4.13 | cellular response to hydrogen peroxide | biological process | GO:0070301 | 62 | 4 | 17256 | 270 |
MAPK13,BNIP3,PLEKHA1,PRKCD |
| 1.609e-02 | -4.13 | Regulation of p38-alpha and p38-beta | Pathway Interaction DB | p38alphabetapathway | 27 | 3 | 2226 | 45 |
FGR,DUSP8,MAP2K6 |
| 1.610e-02 | -4.13 | GO_POSITIVE_REGULATION_OF_CELL_DEATH | MSigDB lists | GO_POSITIVE_REGULATION_OF_CELL_DEATH | 589 | 17 | 17377 | 282 |
MSX1,ARHGEF11,BIK,BNIP3L,WNT11,SAV1,TIAM2,GPLD1,PMAIP1,MYC,RASGRF2,MAP2K6,PRKCD,TNFSF15,BNIP3,DAB2IP,DDIT3 |
| 1.610e-02 | -4.13 | GO_REGULATION_OF_INTRACELLULAR_TRANSPORT | MSigDB lists | GO_REGULATION_OF_INTRACELLULAR_TRANSPORT | 589 | 17 | 17377 | 282 |
MXI1,BVES,UBASH3B,PTPN6,BNIP3L,WWC1,GAS6,PFN2,FGR,PMAIP1,DACT1,WWTR1,PRKCD,DAB2IP,PDE4D,STXBP1,PKIA |
| 1.611e-02 | -4.13 | chr2p21 | MSigDB lists | chr2p21 | 33 | 3 | 17377 | 282 |
ATP6V1E2,EPCAM,EHD3 |
| 1.611e-02 | -4.13 | VALK_AML_CLUSTER_5 | MSigDB lists | VALK_AML_CLUSTER_5 | 33 | 3 | 17377 | 282 |
MAFB,FAM198B,SMPDL3A |
| 1.611e-02 | -4.13 | GARGALOVIC_RESPONSE_TO_OXIDIZED_PHOSPHOLIPIDS_BLACK_UP | MSigDB lists | GARGALOVIC_RESPONSE_TO_OXIDIZED_PHOSPHOLIPIDS_BLACK_UP | 33 | 3 | 17377 | 282 |
RHPN2,TRIB3,ABHD4 |
| 1.611e-02 | -4.13 | BURTON_ADIPOGENESIS_1 | MSigDB lists | BURTON_ADIPOGENESIS_1 | 33 | 3 | 17377 | 282 |
SGK1,DLX2,MYC |
| 1.611e-02 | -4.13 | GO_POSITIVE_REGULATION_OF_SODIUM_ION_TRANSPORT | MSigDB lists | GO_POSITIVE_REGULATION_OF_SODIUM_ION_TRANSPORT | 33 | 3 | 17377 | 282 |
SGK1,SCN5A,SGK2 |
| 1.614e-02 | -4.13 | bilirubin transmembrane transporter activity | molecular function | GO:0015127 | 1 | 1 | 17224 | 278 |
ABCC2 |
| 1.614e-02 | -4.13 | succinate-semialdehyde dehydrogenase binding | molecular function | GO:0032145 | 1 | 1 | 17224 | 278 |
ABAT |
| 1.614e-02 | -4.13 | myo-inositol:proton symporter activity | molecular function | GO:0005366 | 1 | 1 | 17224 | 278 |
SLC2A13 |
| 1.614e-02 | -4.13 | arachidonic acid 11,12-epoxygenase activity | molecular function | GO:0008405 | 1 | 1 | 17224 | 278 |
CYP2J2 |
| 1.614e-02 | -4.13 | voltage-gated sodium channel activity involved in AV node cell action potential | molecular function | GO:0086060 | 1 | 1 | 17224 | 278 |
SCN5A |
| 1.614e-02 | -4.13 | A2A adenosine receptor binding | molecular function | GO:0031687 | 1 | 1 | 17224 | 278 |
NECAB2 |
| 1.614e-02 | -4.13 | riboflavin reductase (NADPH) activity | molecular function | GO:0042602 | 1 | 1 | 17224 | 278 |
BLVRB |
| 1.614e-02 | -4.13 | voltage-gated sodium channel activity involved in bundle of His cell action potential | molecular function | GO:0086061 | 1 | 1 | 17224 | 278 |
SCN5A |
| 1.614e-02 | -4.13 | arachidonic acid 14,15-epoxygenase activity | molecular function | GO:0008404 | 1 | 1 | 17224 | 278 |
CYP2J2 |
| 1.614e-02 | -4.13 | L-tryptophan transmembrane transporter activity | molecular function | GO:0015196 | 1 | 1 | 17224 | 278 |
SLC36A4 |
| 1.614e-02 | -4.13 | 4-aminobutyrate transaminase activity | molecular function | GO:0003867 | 1 | 1 | 17224 | 278 |
ABAT |
| 1.614e-02 | -4.13 | 4-aminobutyrate:2-oxoglutarate transaminase activity | molecular function | GO:0034386 | 1 | 1 | 17224 | 278 |
ABAT |
| 1.614e-02 | -4.13 | glycosylphosphatidylinositol phospholipase D activity | molecular function | GO:0004621 | 1 | 1 | 17224 | 278 |
GPLD1 |
| 1.614e-02 | -4.13 | xylosylprotein 4-beta-galactosyltransferase activity | molecular function | GO:0046525 | 1 | 1 | 17224 | 278 |
B4GALT7 |
| 1.614e-02 | -4.13 | voltage-gated sodium channel activity involved in SA node cell action potential | molecular function | GO:0086063 | 1 | 1 | 17224 | 278 |
SCN5A |
| 1.614e-02 | -4.13 | uroporphyrinogen-III synthase activity | molecular function | GO:0004852 | 1 | 1 | 17224 | 278 |
UROS |
| 1.614e-02 | -4.13 | iron channel activity | molecular function | GO:0097689 | 1 | 1 | 17224 | 278 |
SLC40A1 |
| 1.614e-02 | -4.13 | poly-glutamine tract binding | molecular function | GO:0008267 | 1 | 1 | 17224 | 278 |
RERE |
| 1.614e-02 | -4.13 | peptidyl-cysteine S-nitrosylase activity | molecular function | GO:0035605 | 1 | 1 | 17224 | 278 |
GAPDH |
| 1.614e-02 | -4.13 | kynurenine 3-monooxygenase activity | molecular function | GO:0004502 | 1 | 1 | 17224 | 278 |
KMO |
| 1.614e-02 | -4.13 | linoleic acid epoxygenase activity | molecular function | GO:0071614 | 1 | 1 | 17224 | 278 |
CYP2J2 |
| 1.614e-02 | -4.13 | ADP-D-ribose binding | molecular function | GO:0072570 | 1 | 1 | 17224 | 278 |
PARP9 |
| 1.614e-02 | -4.13 | collagen fibril binding | molecular function | GO:0098633 | 1 | 1 | 17224 | 278 |
CHADL |
| 1.614e-02 | -4.13 | (S)-3-amino-2-methylpropionate transaminase activity | molecular function | GO:0047298 | 1 | 1 | 17224 | 278 |
ABAT |
| 1.622e-02 | -4.12 | Signaling mediated by p38-gamma and p38-delta | Pathway Interaction DB | p38gammadeltapathway | 10 | 2 | 2226 | 45 |
MAPK13,MAP2K6 |
| 1.623e-02 | -4.12 | prostate-carcinoma-adenocarcinoma | COSMIC cancer mutations | prostate-carcinoma-adenocarcinoma | 12749 | 222 | 17385 | 281 |
ARHGAP26,CCDC126,ACSL1,ACVR1,DUSP8,LGR4,RECK,HEBP1,PTPN21,ALG1L,NDRG2,SLC2A13,ITPR2,ABAT,PRKCA,ABHD4,CACNB4,ABHD6,HMCN1,NCS1,EPDR1,EPCAM,CPNE2,FKBP9,PPM1E,DLX6,CFHR1,TMEM143,TMEM37,TLN2,TSHR,FANK1,TBC1D8,PGBD5,KLHL3,WISP3,EXOC6B,DSTN,CAPN5,BNIP3L,SLC25A28,TTC22,ABCC2,TNS1,PLEKHA1,SAV1,SPATA9,TCF7L1,RASGRF2,ARHGAP28,MAPK13,TMOD2,TANC2,APBA2,LONRF1,GPR63,SCN5A,RGS16,TMEM63C,RUNX2,ZNF395,ZHX3,BVES,UBASH3B,CYP2J2,FBXO4,CYP4V2,SETBP1,ATP6V1E2,CHADL,SLC36A4,TNFRSF10C,PFN2,SATB1,DYNC1I1,HPCAL4,FHOD3,MTUS1,IL17D,NUMBL,RALGPS2,SLC30A4,MYC,ZIC5,EBF4,SRGAP1,GAN,NCEH1,MOXD1,VGLL4,STXBP1,GPR161,EPB41L5,BDNF,QSOX1,WDR25,WWC1,STRADB,SHISA2,PRDM1,LHPP,ARRDC4,OR11H4,B4GALNT3,ZNF558,ADAMTS3,KIAA0355,ISM1,LRRIQ3,EMILIN2,HK2,CLMN,RNF122,ZNF516,RASAL2,DOCK1,ST14,FAM131C,CCDC110,PLXNA2,RHPN2,FAM198B,COLEC10,KIF21B,RADIL,CBLN1,TIAM2,TMEM53,ZNF827,KMO,RPS6KL1,DACT1,ZNF521,EEPD1,ZDHHC23,MAP7,DAB2IP,MYH15,PJA1,RAB27B,DNAH5,TMEM120B,FAM78B,ATP6AP1L,HSPA2,C3orf67,DZANK1,PHLDB2,GAPDH,PDK1,SLC39A8,PTPN6,CYB5R2,SFXN4,ADCY1,NLGN4X,SATB2,WNT11,RAB38,TBC1D16,TRIQK,JAM3,IQCK,IFT81,LMLN,ANKRD31,WFS1,RBPMS2,WWTR1,PLEKHG1,P4HA1,TNFSF15,DISP1,KLHL31,COBL,CCDC148,MXI1,TMEM132C,PRSS16,ARHGEF11,BACE1,BIK,BLVRB,CCNJL,KIF5C,ARL2,OVOL2,ZNF219,NEO1,RGS17,GPR155,PRKCD,EHD3,GTF2F2,ACTA2,CCDC122,PRICKLE2,SGK1,KIAA0408,SMPDL3A,PARP9,TMC7,MN1,B9D1,SLC40A1,PXN,MPP1,OGDHL,EXOG,PALLD,GPR137C,RERE,GPLD1,CTIF,FGR,MAP2K6,GNAO1,FMO4,KIAA0513,MYOM2,B4GALT7,PHC1 |
| 1.626e-02 | -4.12 | GO_LEUKOCYTE_HOMEOSTASIS | MSigDB lists | GO_LEUKOCYTE_HOMEOSTASIS | 60 | 4 | 17377 | 282 |
SLC40A1,TNFRSF17,PMAIP1,JAM3 |
| 1.626e-02 | -4.12 | CADWELL_ATG16L1_TARGETS_DN | MSigDB lists | CADWELL_ATG16L1_TARGETS_DN | 60 | 4 | 17377 | 282 |
P4HA1,SGK1,SATB2,RALGPS2 |
| 1.626e-02 | -4.12 | BURTON_ADIPOGENESIS_PEAK_AT_0HR | MSigDB lists | BURTON_ADIPOGENESIS_PEAK_AT_0HR | 60 | 4 | 17377 | 282 |
ACTA2,RASL11B,TRIB3,DDIT3 |
| 1.627e-02 | -4.12 | ATF5 (activating transcription factor 5) | protein interactions | 22809 | 12 | 2 | 17029 | 283 |
TRIB3,CEBPA |
| 1.627e-02 | -4.12 | LRRTM2 (leucine rich repeat transmembrane neuronal 2) | protein interactions | 26045 | 12 | 2 | 17029 | 283 |
ACTA2,LGR4 |
| 1.627e-02 | -4.12 | RBM18 (RNA binding motif protein 18) | protein interactions | 92400 | 12 | 2 | 17029 | 283 |
ACTA2,TMOD2 |
| 1.627e-02 | -4.12 | MS4A2 (membrane spanning 4-domains A2) | protein interactions | 2206 | 12 | 2 | 17029 | 283 |
PTPN6,PRKCD |
| 1.632e-02 | -4.12 | GO_CELL_JUNCTION_ASSEMBLY | MSigDB lists | GO_CELL_JUNCTION_ASSEMBLY | 125 | 6 | 17377 | 282 |
ARL2,TNS1,WNT11,TLN2,PRKCA,MARVELD2 |
| 1.635e-02 | -4.11 | cell leading edge | cellular component | GO:0031252 | 385 | 12 | 18223 | 280 |
EPB41L5,PHLDB2,FGR,PXN,SPATA13,ACTA2,WWC1,PLEKHA1,PALLD,TLN2,COBL,TIAM2 |
| 1.637e-02 | -4.11 | APOA1 (apolipoprotein A1) | protein interactions | 335 | 89 | 5 | 17029 | 283 |
TNFRSF10C,ZNF558,CFHR1,SMPDL3A,GPLD1 |
| 1.641e-02 | -4.11 | zymogen granule | cellular component | GO:0042588 | 13 | 2 | 18223 | 280 |
SCAMP1,RAB27B |
| 1.644e-02 | -4.11 | BACK | interpro domains | IPR011705 | 61 | 4 | 18492 | 296 |
KLHL31,KLHL3,KLHL23,GAN |
| 1.646e-02 | -4.11 | actin binding | molecular function | GO:0003779 | 411 | 13 | 17224 | 278 |
KLHL3,DSTN,ALDOA,CLMN,MYOM2,MYH15,TNS1,TMOD2,PALLD,TLN2,PFN2,COBL,FHOD3 |
| 1.658e-02 | -4.10 | skin-face-carcinoma-squamous_cell_carcinoma | COSMIC cancer mutations | skin-face-carcinoma-squamous_cell_carcinoma | 2079 | 46 | 17385 | 281 |
ACSL1,ZHX3,BVES,ST14,ARHGEF11,CYP2J2,PTPN21,PLXNA2,SETBP1,RHPN2,ITPR2,KIF21B,DYNC1I1,RADIL,HMCN1,FHOD3,RGS17,RALGPS2,KMO,ZNF521,SRGAP1,KIAA0408,TLN2,DNAH5,C3orf67,TMC7,QSOX1,SLC39A8,SOX21,ADCY1,ABCC2,WNT11,PRDM1,PALLD,ZNF558,RERE,SPNS1,RASGRF2,LRRIQ3,EMILIN2,HK2,CLMN,MYOM2,SMYD3,COBL,B4GALT7 |
| 1.662e-02 | -4.10 | Prkcz (protein kinase C, zeta) | protein interactions | 25522 | 1 | 1 | 17029 | 283 |
WWC1 |
| 1.662e-02 | -4.10 | MSS4 (1-phosphatidylinositol-4-phosphate 5-kinase) | protein interactions | 851789 | 1 | 1 | 17029 | 283 |
PLEKHA1 |
| 1.662e-02 | -4.10 | Usp39 (ubiquitin specific peptidase 39) | protein interactions | 28035 | 1 | 1 | 17029 | 283 |
ACVR1 |
| 1.662e-02 | -4.10 | Ptpn6 (protein tyrosine phosphatase, non-receptor type 6) | protein interactions | 116689 | 1 | 1 | 17029 | 283 |
MTUS1 |
| 1.662e-02 | -4.10 | Cdon (cell adhesion molecule-related/down-regulated by oncogenes) | protein interactions | 57810 | 1 | 1 | 17029 | 283 |
NEO1 |
| 1.662e-02 | -4.10 | ARAP2 (ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2) | protein interactions | 116984 | 1 | 1 | 17029 | 283 |
ARHGEF11 |
| 1.662e-02 | -4.10 | CSNK2B (casein kinase 2 beta) | protein interactions | 539235 | 1 | 1 | 17029 | 283 |
MYC |
| 1.662e-02 | -4.10 | Bcl2 (B cell leukemia/lymphoma 2) | protein interactions | 12043 | 1 | 1 | 17029 | 283 |
PXN |
| 1.662e-02 | -4.10 | ARL2BP (ADP ribosylation factor like GTPase 2 binding protein) | protein interactions | 613462 | 1 | 1 | 17029 | 283 |
ARL2 |
| 1.662e-02 | -4.10 | WEE2 (WEE1 homolog 2) | protein interactions | 494551 | 1 | 1 | 17029 | 283 |
MYC |
| 1.662e-02 | -4.10 | ZNF469 (zinc finger protein 469) | protein interactions | 84627 | 1 | 1 | 17029 | 283 |
GAN |
| 1.662e-02 | -4.10 | CCDC157 (coiled-coil domain containing 157) | protein interactions | 550631 | 1 | 1 | 17029 | 283 |
LGR4 |
| 1.662e-02 | -4.10 | NPC1L1 (NPC1 like intracellular cholesterol transporter 1) | protein interactions | 29881 | 1 | 1 | 17029 | 283 |
LGR4 |
| 1.662e-02 | -4.10 | CSNK2A1 (casein kinase 2 alpha 1) | protein interactions | 282419 | 1 | 1 | 17029 | 283 |
MYC |
| 1.662e-02 | -4.10 | ASPG (asparaginase) | protein interactions | 374569 | 1 | 1 | 17029 | 283 |
SGK1 |
| 1.662e-02 | -4.10 | MIR17HG (miR-17-92a-1 cluster host gene) | protein interactions | 407975 | 1 | 1 | 17029 | 283 |
MYC |
| 1.662e-02 | -4.10 | GNB1 (G protein subunit beta 1) | protein interactions | 281201 | 1 | 1 | 17029 | 283 |
DYNC1I1 |
| 1.662e-02 | -4.10 | TMEM89 (transmembrane protein 89) | protein interactions | 440955 | 1 | 1 | 17029 | 283 |
C4A |
| 1.662e-02 | -4.10 | IQCF2 (IQ motif containing F2) | protein interactions | 389123 | 1 | 1 | 17029 | 283 |
LONRF1 |
| 1.662e-02 | -4.10 | NTN3 (netrin 3) | protein interactions | 4917 | 1 | 1 | 17029 | 283 |
NEO1 |
| 1.662e-02 | -4.10 | MXRA5 (matrix remodeling associated 5) | protein interactions | 25878 | 1 | 1 | 17029 | 283 |
GAN |
| 1.662e-02 | -4.10 | Apba2 (amyloid beta precursor protein binding family A member 2) | protein interactions | 83610 | 1 | 1 | 17029 | 283 |
STXBP1 |
| 1.662e-02 | -4.10 | Ajuba (ajuba LIM protein) | protein interactions | 16475 | 1 | 1 | 17029 | 283 |
ACVR1 |
| 1.662e-02 | -4.10 | GALR3 (galanin receptor 3) | protein interactions | 8484 | 1 | 1 | 17029 | 283 |
MYC |
| 1.662e-02 | -4.10 | YPK1 (serine/threonine protein kinase YPK1) | protein interactions | 853733 | 1 | 1 | 17029 | 283 |
SGK1 |
| 1.662e-02 | -4.10 | CUZD1 (CUB and zona pellucida like domains 1) | protein interactions | 50624 | 1 | 1 | 17029 | 283 |
PTPN6 |
| 1.662e-02 | -4.10 | PPP5D1 (PPP5 tetratricopeptide repeat domain containing 1) | protein interactions | 100506012 | 1 | 1 | 17029 | 283 |
DUSP8 |
| 1.662e-02 | -4.10 | DNAH10 (dynein axonemal heavy chain 10) | protein interactions | 196385 | 1 | 1 | 17029 | 283 |
GAN |
| 1.662e-02 | -4.10 | RPL23AP32 (ribosomal protein L23a pseudogene 32) | protein interactions | 56969 | 1 | 1 | 17029 | 283 |
MXI1 |
| 1.662e-02 | -4.10 | mdfic.S (MyoD family inhibitor domain containing S homeolog) | protein interactions | 398213 | 1 | 1 | 17029 | 283 |
TCF7L1 |
| 1.662e-02 | -4.10 | CCDC73 (coiled-coil domain containing 73) | protein interactions | 493860 | 1 | 1 | 17029 | 283 |
GAN |
| 1.662e-02 | -4.10 | Rabac1 (Rab acceptor 1 (prenylated)) | protein interactions | 14470 | 1 | 1 | 17029 | 283 |
SGK1 |
| 1.662e-02 | -4.10 | pin1.S (peptidylprolyl cis/trans isomerase, NIMA-interacting 1 S homeolog) | protein interactions | 503670 | 1 | 1 | 17029 | 283 |
MYC |
| 1.662e-02 | -4.10 | Ntn3 (netrin 3) | protein interactions | 18209 | 1 | 1 | 17029 | 283 |
NEO1 |
| 1.662e-02 | -4.10 | Fgd6 (FYVE, RhoGEF and PH domain containing 6) | protein interactions | 13998 | 1 | 1 | 17029 | 283 |
ACVR1 |
| 1.662e-02 | -4.10 | RSPO4 (R-spondin 4) | protein interactions | 343637 | 1 | 1 | 17029 | 283 |
LGR4 |
| 1.662e-02 | -4.10 | Stx5 (syntaxin 5) | protein interactions | 65134 | 1 | 1 | 17029 | 283 |
STXBP1 |
| 1.662e-02 | -4.10 | Cdh2 (cadherin 2) | protein interactions | 12558 | 1 | 1 | 17029 | 283 |
NEO1 |
| 1.662e-02 | -4.10 | BRI3 (brain protein I3) | protein interactions | 25798 | 1 | 1 | 17029 | 283 |
BACE1 |
| 1.662e-02 | -4.10 | FAM209A (family with sequence similarity 209 member A) | protein interactions | 200232 | 1 | 1 | 17029 | 283 |
UBASH3B |
| 1.662e-02 | -4.10 | Cdh15 (cadherin 15) | protein interactions | 12555 | 1 | 1 | 17029 | 283 |
NEO1 |
| 1.662e-02 | -4.10 | H1FX-AS1 (H1FX antisense RNA 1) | protein interactions | 339942 | 1 | 1 | 17029 | 283 |
PTPN6 |
| 1.662e-02 | -4.10 | Ube2r2 (ubiquitin-conjugating enzyme E2R 2) | protein interactions | 67615 | 1 | 1 | 17029 | 283 |
ACVR1 |
| 1.662e-02 | -4.10 | Mdfi (MyoD family inhibitor) | protein interactions | 17240 | 1 | 1 | 17029 | 283 |
TCF7L1 |
| 1.662e-02 | -4.10 | Apba1 (amyloid beta precursor protein binding family A member 1) | protein interactions | 83589 | 1 | 1 | 17029 | 283 |
STXBP1 |
| 1.663e-02 | -4.10 | TMEM185A (transmembrane protein 185A) | protein interactions | 84548 | 59 | 4 | 17029 | 283 |
CPNE2,PRKCA,NCS1,EEPD1 |
| 1.673e-02 | -4.09 | cell-cell junction assembly | biological process | GO:0007043 | 95 | 5 | 17256 | 270 |
ARL2,WNT11,TLN2,PRKCA,MARVELD2 |
| 1.675e-02 | -4.09 | SAM_MT43_2 | prosite domains | PS51574 | 1 | 1 | 12060 | 202 |
SMYD3 |
| 1.675e-02 | -4.09 | EPENDYMIN_1 | prosite domains | PS00898 | 1 | 1 | 12060 | 202 |
EPDR1 |
| 1.675e-02 | -4.09 | EPENDYMIN_2 | prosite domains | PS00899 | 1 | 1 | 12060 | 202 |
EPDR1 |
| 1.677e-02 | -4.09 | V$AREB6_03 | MSigDB lists | V$AREB6_03 | 240 | 9 | 17377 | 282 |
ARHGAP26,EPCAM,STRADB,NUMBL,FGR,VGLL4,DSTN,HMCN1,MTUS1 |
| 1.680e-02 | -4.09 | regulation of organ morphogenesis | biological process | GO:2000027 | 249 | 9 | 17256 | 270 |
ENAM,RUNX2,MSX1,ACVR1,LGR4,DACT1,MYC,PRICKLE2,WNT11 |
| 1.685e-02 | -4.08 | positive regulation of transferase activity | biological process | GO:0051347 | 663 | 18 | 17256 | 270 |
ACSL1,ADCY1,STRADB,WNT11,GAS6,ACVR2B,ARRDC4,TLR6,TRIB3,FGR,MAP2K6,MYC,ERN1,PRKCD,INAVA,DAB2IP,TNFSF15,EPHB6 |
| 1.688e-02 | -4.08 | positive regulation of signal transduction | biological process | GO:0009967 | 1600 | 36 | 17256 | 270 |
ACVR1,NECAB2,LGR4,BIK,GAS6,TNFRSF10C,ABAT,PRKCA,MYORG,NEO1,PMAIP1,DACT1,PRKCD,RASD2,INAVA,DAB2IP,BNIP3,EPHB6,PARP9,BDNF,MSX1,PTPN6,WWC1,WNT11,GAREM1,ACVR2B,TLR6,FGR,ADAMTS3,MAP2K6,PLK2,ERN1,TNFSF15,TMOD2,DISP1,DDIT3 |
| 1.691e-02 | -4.08 | RB_P130_DN.V1_DN | MSigDB lists | RB_P130_DN.V1_DN | 126 | 6 | 17377 | 282 |
BNIP3,SCAMP1,ARRDC4,SOX21,PARP9,HK2 |
| 1.691e-02 | -4.08 | GO_NEGATIVE_REGULATION_OF_PROTEIN_SERINE_THREONINE_KINASE_ACTIVITY | MSigDB lists | GO_NEGATIVE_REGULATION_OF_PROTEIN_SERINE_THREONINE_KINASE_ACTIVITY | 126 | 6 | 17377 | 282 |
CEBPA,DAB2IP,DUSP8,PTPN6,PRKCD,PKIA |
| 1.691e-02 | -4.08 | GO_REGULATION_OF_CAMP_METABOLIC_PROCESS | MSigDB lists | GO_REGULATION_OF_CAMP_METABOLIC_PROCESS | 126 | 6 | 17377 | 282 |
PDE4D,PRKCA,TSHR,WFS1,GPR161,ADCY1 |
| 1.698e-02 | -4.08 | positive regulation of mast cell degranulation | biological process | GO:0043306 | 13 | 2 | 17256 | 270 |
FGR,STXBP1 |
| 1.698e-02 | -4.08 | negative regulation of protein import | biological process | GO:1904590 | 13 | 2 | 17256 | 270 |
GAS6,PKIA |
| 1.698e-02 | -4.08 | positive regulation of mast cell activation involved in immune response | biological process | GO:0033008 | 13 | 2 | 17256 | 270 |
FGR,STXBP1 |
| 1.698e-02 | -4.08 | regulation of natural killer cell differentiation | biological process | GO:0032823 | 13 | 2 | 17256 | 270 |
PRDM1,GAS6 |
| 1.698e-02 | -4.08 | regulation of transcription from RNA polymerase II promoter involved in heart development | biological process | GO:1901213 | 13 | 2 | 17256 | 270 |
MSX1,ACVR1 |
| 1.698e-02 | -4.08 | negative regulation of protein import into nucleus | biological process | GO:0042308 | 13 | 2 | 17256 | 270 |
GAS6,PKIA |
| 1.700e-02 | -4.07 | GO_MONOOXYGENASE_ACTIVITY | MSigDB lists | GO_MONOOXYGENASE_ACTIVITY | 92 | 5 | 17377 | 282 |
MOXD1,KMO,FMO4,CYP2J2,CYP4V2 |
| 1.701e-02 | -4.07 | human chr2q24.1 | chromosome location | human chr2q24.1 | 16 | 2 | 26185 | 331 |
CCDC148,ACVR1 |
| 1.704e-02 | -4.07 | Photodynamic therapy-induced unfolded protein response | WikiPathways | WP3613 | 29 | 3 | 5312 | 101 |
TRIB3,ERN1,DDIT3 |
| 1.704e-02 | -4.07 | T-Cell Receptor and Co-stimulatory Signaling | WikiPathways | WP2583 | 29 | 3 | 5312 | 101 |
PDK1,PRKCA,PTPN6 |
| 1.711e-02 | -4.07 | Rho GTPase cycle | REACTOME pathways | R-HSA-194840 | 143 | 6 | 10287 | 148 |
ARHGAP28,ARHGAP26,ARHGEF11,RASGRF2,TIAM2,SRGAP1 |
| 1.714e-02 | -4.07 | negative regulation of toll-like receptor signaling pathway | biological process | GO:0034122 | 35 | 3 | 17256 | 270 |
DAB2IP,LGR4,TLR6 |
| 1.714e-02 | -4.07 | response to ischemia | biological process | GO:0002931 | 35 | 3 | 17256 | 270 |
BVES,MAP2K6,HK2 |
| 1.715e-02 | -4.07 | TWNK (twinkle mtDNA helicase) | protein interactions | 56652 | 33 | 3 | 17029 | 283 |
EPB41L5,PHLDB2,B4GALT7 |
| 1.715e-02 | -4.07 | AKAP12 (A-kinase anchoring protein 12) | protein interactions | 9590 | 33 | 3 | 17029 | 283 |
PDE4D,SAV1,PRKCA |
| 1.715e-02 | -4.07 | AFAP1 (actin filament associated protein 1) | protein interactions | 60312 | 33 | 3 | 17029 | 283 |
PRKCA,MYC,PRKCD |
| 1.718e-02 | -4.06 | neuron differentiation | biological process | GO:0030182 | 966 | 24 | 17256 | 270 |
BDNF,RUNX2,PLXNA2,EFNA3,ADCY1,KIF5C,NLGN4X,SATB2,WNT11,PRDM1,PRKCA,JAM3,CBLN1,RERE,NEO1,NUMBL,GNAO1,ZNF521,SGK1,CLMN,DAB2IP,DLX2,STXBP1,COBL |
| 1.719e-02 | -4.06 | V$PXR_Q2 | MSigDB lists | V$PXR_Q2 | 241 | 9 | 17377 | 282 |
BDNF,FGR,HEBP1,ALDOA,PLXNA2,NDRG2,TNFSF15,TNS1,PLEKHA1 |
| 1.719e-02 | -4.06 | DAVICIONI_TARGETS_OF_PAX_FOXO1_FUSIONS_UP | MSigDB lists | DAVICIONI_TARGETS_OF_PAX_FOXO1_FUSIONS_UP | 241 | 9 | 17377 | 282 |
SGK1,MN1,CLMN,TCF7L1,ABAT,ZNF395,PRKCA,SATB1,HEBP1 |
| 1.719e-02 | -4.06 | GO_CUL3_RING_UBIQUITIN_LIGASE_COMPLEX | MSigDB lists | GO_CUL3_RING_UBIQUITIN_LIGASE_COMPLEX | 61 | 4 | 17377 | 282 |
KLHL31,KLHL3,KLHL23,GAN |
| 1.720e-02 | -4.06 | regulation of protein stability | biological process | GO:0031647 | 250 | 9 | 17256 | 270 |
MSX1,GAPDH,DACT1,FBXO4,WFS1,PRKCD,SAV1,STXBP1,PFN2 |
| 1.722e-02 | -4.06 | GSE6269_FLU_VS_STAPH_AUREUS_INF_PBMC_DN | MSigDB lists | GSE6269_FLU_VS_STAPH_AUREUS_INF_PBMC_DN | 163 | 7 | 17377 | 282 |
GAPDH,ACSL1,MPP1,BLVRB,EMILIN2,CTIF,BNIP3L |
| 1.726e-02 | -4.06 | metal ion transport | biological process | GO:0030001 | 616 | 17 | 17256 | 270 |
SLC40A1,SCN5A,KLHL3,SLC9C1,SLC39A8,ATOX1,ATP6V1E2,ABCC2,SLC25A28,ITPR2,GAS6,CACNB4,NCS1,SLC30A4,SGK1,TMEM37,DDIT3 |
| 1.742e-02 | -4.05 | central_nervous_system-brain-glioma-astrocytoma_Grade_IV | COSMIC cancer mutations | central_nervous_system-brain-glioma-astrocytoma_Grade_IV | 16307 | 272 | 17385 | 281 |
ARHGAP26,ACVR1,DUSP8,LGR4,RECK,LSM11,ALG1L,CEBPA,PRKCA,ABHD6,NCS1,EPDR1,PMAIP1,CFHR1,TMEM37,TSHR,TBC1D8,KLHL23,KLHL3,WISP3,EXOC6B,DSTN,BNIP3L,SLC25A28,ABCC2,TNS1,ACVR2B,SAV1,SPATA9,PLK2,RASGRF2,ALDOA,ARHGAP28,MAPK13,TMOD2,TANC2,SCN5A,ZHX3,CYP2J2,SLC36A4,TNFRSF10C,DYNC1I1,HPCAL4,NIPSNAP3B,MTUS1,IL17D,RALGPS2,MYC,ZIC5,SRGAP1,MOXD1,STXBP1,GPR161,EPB41L5,BDNF,QSOX1,SHISA2,ARRDC4,OR11H4,ZNF558,ADAMTS3,ISM1,LRRIQ3,QPCTL,EMILIN2,CLMN,IQSEC2,SMYD3,ZNF516,RASAL2,ST14,FAM131C,CCDC110,PLXNA2,COLEC10,TIAM2,TMEM53,ZNF827,KMO,DACT1,DAB2IP,PJA1,PDE4D,RAB27B,DNAH5,ATP6AP1L,KIAA1549,C3orf67,GAPDH,PDK1,SOX21,CYB5R2,SFXN4,ADCY1,NLGN4X,SATB2,WNT11,RAB38,TBC1D16,IQCK,WFS1,WWTR1,PLEKHG1,P4HA1,TNFSF15,DBP,COBL,KCTD1,C2orf88,CCDC148,MXI1,TMEM132C,BACE1,BIK,CCNJL,KIF5C,GAS6,ZNF219,NEO1,RGS17,GPR155,SMPDL3A,PARP9,TMC7,MN1,B9D1,SLC40A1,PXN,MPP1,GPR137C,GPLD1,TRIB3,FGR,GNAO1,MYOM2,TNFRSF17,DDIT3,B4GALT7,PHC1,CCDC126,ACSL1,HEBP1,PTPN21,NDRG2,NRN1,ABAT,ITPR2,SLC2A13,CACNB4,ABHD4,HMCN1,EPCAM,PPM1E,FKBP9,CPNE2,MARVELD2,DLX6,TMEM143,TLN2,FANK1,OR2W3,ZNF391,PGBD5,PNRC1,CAPN5,ATOX1,TTC22,PLEKHA1,SGK2,NT5DC2,PLEKHB1,DYRK1B,SPNS1,TCF7L1,ERN1,DLX2,APBA2,GPR63,LONRF1,RGS16,RUNX2,ZNF395,BVES,FBXO4,UBASH3B,CYP4V2,ATP6V1E2,RASL11B,SETBP1,CHADL,SATB1,PFN2,FHOD3,NUMBL,SLC30A4,GAN,EBF4,BNIP3,NCEH1,VGLL4,BARX1,IL17RD,SPATA13,EFNA3,MAFB,STRADB,WWC1,WDR25,PPFIA4,LHPP,PRDM1,B4GALNT3,KIAA0355,HK2,RNF122,DOCK1,RHPN2,FAM198B,KIF21B,RADIL,CBLN1,KCTD15,RPS6KL1,ZDHHC23,EEPD1,ZNF521,MAP7,MYH15,TMEM120B,HSPA2,FAM78B,PHLDB2,UROS,PTPN6,SLC39A8,JAM3,CENPV,IFT81,LMLN,ANKRD31,RBPMS2,DISP1,NECAB2,PRSS16,ARHGEF11,BLVRB,OVOL2,PRKCD,RASD2,EHD3,GTF2F2,ACTA2,PRICKLE2,TRIM3,SGK1,CCDC122,KIAA0408,MSX1,NUAK2,OGDHL,EXOG,PALLD,TLR6,CTIF,RERE,FMO4,MAP2K6,KIAA0513,ZNF474,THAP10,RNF157,PKIA |
| 1.744e-02 | -4.05 | LINDGREN_BLADDER_CANCER_CLUSTER_2B | MSigDB lists | LINDGREN_BLADDER_CANCER_CLUSTER_2B | 368 | 12 | 17377 | 282 |
RUNX2,C4A,MPP1,RBPMS2,ACTA2,MAFB,NRN1,TNS1,MOXD1,PALLD,JAM3,TBC1D8 |
| 1.746e-02 | -4.05 | GO_NADH_METABOLIC_PROCESS | MSigDB lists | GO_NADH_METABOLIC_PROCESS | 34 | 3 | 17377 | 282 |
GAPDH,ALDOA,HK2 |
| 1.746e-02 | -4.05 | GO_CAMP_METABOLIC_PROCESS | MSigDB lists | GO_CAMP_METABOLIC_PROCESS | 34 | 3 | 17377 | 282 |
PDE4D,CACNB4,ADCY1 |
| 1.746e-02 | -4.05 | PLASARI_TGFB1_TARGETS_1HR_UP | MSigDB lists | PLASARI_TGFB1_TARGETS_1HR_UP | 34 | 3 | 17377 | 282 |
RASL11B,NUAK2,SPATA13 |
| 1.752e-02 | -4.04 | GSE45365_NK_CELL_VS_BCELL_DN | MSigDB lists | GSE45365_NK_CELL_VS_BCELL_DN | 127 | 6 | 17377 | 282 |
SPATA9,MXI1,PDE4D,PDK1,ATOX1,TMEM143 |
| 1.756e-02 | -4.04 | ZHANG_TLX_TARGETS_60HR_UP | MSigDB lists | ZHANG_TLX_TARGETS_60HR_UP | 283 | 10 | 17377 | 282 |
RALGPS2,PNRC1,DUSP8,CYP2J2,WWTR1,ABAT,ABHD4,APBA2,DDIT3,CTIF |
| 1.764e-02 | -4.04 | Rap1 signaling pathway | KEGG pathways | ko04015 | 210 | 8 | 7161 | 113 |
MAP2K6,GNAO1,EFNA3,ADCY1,MAPK13,PRKCA,TLN2,PFN2 |
| 1.764e-02 | -4.04 | Rap1 signaling pathway | KEGG pathways | hsa04015 | 210 | 8 | 7161 | 113 |
MAP2K6,GNAO1,EFNA3,ADCY1,MAPK13,PRKCA,TLN2,PFN2 |
| 1.770e-02 | -4.03 | negative regulation of cytoskeleton organization | biological process | GO:0051494 | 132 | 6 | 17256 | 270 |
ARHGAP28,PHLDB2,TMOD2,PFN2,PRKCD,FHOD3 |
| 1.771e-02 | -4.03 | coenzyme biosynthetic process | biological process | GO:0009108 | 170 | 7 | 17256 | 270 |
ACSL1,GAPDH,KMO,ALDOA,PARP9,OGDHL,HK2 |
| 1.773e-02 | -4.03 | GO_CELLULAR_CHEMICAL_HOMEOSTASIS | MSigDB lists | GO_CELLULAR_CHEMICAL_HOMEOSTASIS | 549 | 16 | 17377 | 282 |
SLC40A1,SLC39A8,ATOX1,ATP6V1E2,ABCC2,RAB38,GAS6,ITPR2,SGK2,CACNB4,WFS1,MYC,ERN1,HK2,SGK1,DDIT3 |
| 1.774e-02 | -4.03 | TURASHVILI_BREAST_LOBULAR_CARCINOMA_VS_LOBULAR_NORMAL_UP | MSigDB lists | TURASHVILI_BREAST_LOBULAR_CARCINOMA_VS_LOBULAR_NORMAL_UP | 93 | 5 | 17377 | 282 |
ACTA2,ISM1,CYP2J2,CYB5R2,FHOD3 |
| 1.775e-02 | -4.03 | GO_STRIATED_MUSCLE_CELL_DIFFERENTIATION | MSigDB lists | GO_STRIATED_MUSCLE_CELL_DIFFERENTIATION | 164 | 7 | 17377 | 282 |
DYRK1B,TMOD2,ACVR1,CACNB4,BVES,SMYD3,FHOD3 |
| 1.775e-02 | -4.03 | GO_POSITIVE_REGULATION_OF_APOPTOTIC_SIGNALING_PATHWAY | MSigDB lists | GO_POSITIVE_REGULATION_OF_APOPTOTIC_SIGNALING_PATHWAY | 164 | 7 | 17377 | 282 |
BNIP3,DAB2IP,MSX1,PMAIP1,PRKCD,DDIT3,BIK |
| 1.776e-02 | -4.03 | calcium channel complex | cellular component | GO:0034704 | 65 | 4 | 18223 | 280 |
CATSPERE,PDE4D,CACNB4,HSPA2 |
| 1.780e-02 | -4.03 | - | gene3d domains | 3.40.1440.10 | 1 | 1 | 8148 | 145 |
SLX1B |
| 1.784e-02 | -4.03 | kidney | COSMIC cancer mutations | kidney | 15842 | 266 | 17385 | 281 |
ARHGAP26,ACVR1,DUSP8,LGR4,RECK,LSM11,CEBPA,PRKCA,ABHD6,NCS1,EPDR1,PMAIP1,CFHR1,TMEM37,TSHR,TBC1D8,KLHL23,KLHL3,EXOC6B,DSTN,BNIP3L,SLC25A28,ABCC2,TNS1,ACVR2B,SAV1,SPATA9,PLK2,RASGRF2,ALDOA,ARHGAP28,MAPK13,TMOD2,TANC2,SCN5A,TMEM63C,ZHX3,CYP2J2,SLC36A4,TNFRSF10C,DYNC1I1,NIPSNAP3B,MTUS1,RALGPS2,MYC,ZIC5,SRGAP1,MOXD1,STXBP1,GPR161,EPB41L5,BDNF,QSOX1,SHISA2,ARRDC4,OR11H4,ZNF558,ADAMTS3,ISM1,LRRIQ3,QPCTL,EMILIN2,CLMN,IQSEC2,SMYD3,ZNF516,RASAL2,ST14,FAM131C,C4A,CCDC110,PLXNA2,COLEC10,TIAM2,TMEM53,ZNF827,KMO,DACT1,DAB2IP,PJA1,PDE4D,RAB27B,DNAH5,ATP6AP1L,KIAA1549,C3orf67,DZANK1,GAPDH,PDK1,SOX21,CYB5R2,SFXN4,ADCY1,NLGN4X,SATB2,WNT11,RAB38,TBC1D16,IQCK,WFS1,WWTR1,PLEKHG1,P4HA1,TNFSF15,DBP,KLHL31,COBL,KCTD1,C2orf88,CCDC148,MXI1,TMEM132C,BACE1,BIK,CCNJL,KIF5C,ARL2,GAS6,ZNF219,NEO1,RGS17,GPR155,PARP9,TMC7,MN1,B9D1,SLC40A1,PXN,MPP1,GPR137C,GPLD1,TRIB3,FGR,GNAO1,MYOM2,TNFRSF17,DDIT3,B4GALT7,PHC1,CCDC126,ACSL1,HEBP1,PTPN21,NDRG2,NRN1,ABAT,ITPR2,SLC2A13,CACNB4,ABHD4,HMCN1,EPCAM,PPM1E,FKBP9,CPNE2,MARVELD2,DLX6,TMEM143,TLN2,FANK1,OR2W3,PGBD5,PNRC1,CAPN5,TTC22,PLEKHA1,SGK2,NT5DC2,PLEKHB1,DYRK1B,SPNS1,TCF7L1,ERN1,APBA2,GPR63,LONRF1,RGS16,RUNX2,ZNF395,BVES,FBXO4,UBASH3B,CYP4V2,ATP6V1E2,RASL11B,SETBP1,CHADL,SATB1,FHOD3,NUMBL,SLC30A4,GAN,EBF4,BNIP3,NCEH1,VGLL4,IL17RD,SPATA13,MAFB,STRADB,WWC1,WDR25,PPFIA4,LHPP,PRDM1,B4GALNT3,KIAA0355,HK2,RNF122,DOCK1,RHPN2,FAM198B,KIF21B,RADIL,CBLN1,KCTD15,RPS6KL1,EEPD1,ZDHHC23,ZNF521,MAP7,MYH15,TMEM120B,HSPA2,FAM78B,PHLDB2,UROS,PTPN6,SLC39A8,JAM3,CENPV,IFT81,LMLN,ANKRD31,RBPMS2,DISP1,NECAB2,PRSS16,ARHGEF11,BLVRB,OVOL2,RASD2,EHD3,PRKCD,GTF2F2,SGK1,PRICKLE2,TRIM3,CCDC122,ACTA2,KIAA0408,MSX1,NUAK2,OGDHL,EXOG,PALLD,TLR6,CTIF,RERE,FMO4,MAP2K6,KIAA0513,ZNF474,THAP10,RNF157,PKIA |
| 1.785e-02 | -4.03 | GO_CELL_PART_MORPHOGENESIS | MSigDB lists | GO_CELL_PART_MORPHOGENESIS | 596 | 17 | 17377 | 282 |
B9D1,BDNF,ADCY1,PLXNA2,EFNA3,KIF5C,NEO1,RERE,IFT81,NUMBL,EHD3,WWTR1,SGK1,DAB2IP,DNAH5,STXBP1,COBL |
| 1.786e-02 | -4.03 | RGS | pfam domains | PF00615 | 35 | 3 | 17054 | 271 |
RGS16,RGS17,GRK3 |
| 1.786e-02 | -4.03 | Kelch_1 | pfam domains | PF01344 | 63 | 4 | 17054 | 271 |
KLHL31,KLHL23,KLHL3,GAN |
| 1.789e-02 | -4.02 | embryonic pattern specification | biological process | GO:0009880 | 64 | 4 | 17256 | 270 |
EPB41L5,SATB2,DISP1,COBL |
| 1.789e-02 | -4.02 | nephron tubule morphogenesis | biological process | GO:0072078 | 64 | 4 | 17256 | 270 |
WNT11,LGR4,KLHL3,MYC |
| 1.789e-02 | -4.02 | AACTTT_UNKNOWN | MSigDB lists | AACTTT_UNKNOWN | 1759 | 40 | 17377 | 282 |
GPR63,SCN5A,MXI1,ARHGEF11,HEBP1,PLXNA2,FAM198B,OVOL2,SLC2A13,COLEC10,ZNF219,SATB1,ABHD4,DYNC1I1,PFN2,ZNF827,PPM1E,KCTD15,CFHR1,DACT1,MYC,ZIC5,ZNF521,SRGAP1,PDE4D,MOXD1,TSHR,MN1,BDNF,KLHL3,SOX21,NUAK2,MAFB,SLC25A28,PRDM1,SAV1,TCF7L1,MAP2K6,RNF122,DDIT3 |
| 1.798e-02 | -4.02 | GO_ADENYL_NUCLEOTIDE_BINDING | MSigDB lists | GO_ADENYL_NUCLEOTIDE_BINDING | 1444 | 34 | 17377 | 282 |
ACVR1,ACSL1,RUNX2,BVES,KIF5C,PRKCA,KIF21B,PFN2,RPS6KL1,EHD3,PRKCD,GTF2F2,ACTA2,SGK1,MYH15,EPHB6,PDE4D,DNAH5,HSPA2,PDK1,ADCY1,NUAK2,STRADB,ABCC2,ACVR2B,SGK2,DYRK1B,TRIB3,FGR,MAP2K6,PLK2,ERN1,HK2,MAPK13 |
| 1.802e-02 | -4.02 | kidney development | biological process | GO:0001822 | 252 | 9 | 17256 | 270 |
EPCAM,LGR4,KLHL3,MYC,WFS1,WWTR1,ACTA2,WNT11,ACVR2B |
| 1.803e-02 | -4.02 | V$OCT_Q6 | MSigDB lists | V$OCT_Q6 | 243 | 9 | 17377 | 282 |
BDNF,MAP2K6,PRICKLE2,TMOD2,PDE4D,PRDM1,DNAH5,HPCAL4,MTUS1 |
| 1.803e-02 | -4.02 | V$COUP_01 | MSigDB lists | V$COUP_01 | 243 | 9 | 17377 | 282 |
ZNF827,MXI1,GAPDH,CFHR1,C4A,ALDOA,PRKCD,DAB2IP,SATB1 |
| 1.803e-02 | -4.02 | STK33_SKM_DN | MSigDB lists | STK33_SKM_DN | 243 | 9 | 17377 | 282 |
RGS16,OGDHL,ZDHHC23,TMEM143,SHISA2,RAB38,RAB27B,TANC2,OR2W3 |
| 1.805e-02 | -4.01 | transmembrane receptor protein tyrosine kinase signaling pathway | biological process | GO:0007169 | 523 | 15 | 17256 | 270 |
BDNF,FGR,PXN,DOCK1,UBASH3B,GTF2F2,EFNA3,ATP6V1E2,MAPK13,GAREM1,DAB2IP,EPHB6,PLEKHA1,PRKCA,GPLD1 |
| 1.806e-02 | -4.01 | GO_REGULATION_OF_PHOSPHORUS_METABOLIC_PROCESS | MSigDB lists | GO_REGULATION_OF_PHOSPHORUS_METABOLIC_PROCESS | 1549 | 36 | 17377 | 282 |
ACVR1,ACSL1,DUSP8,UBASH3B,NDRG2,CEBPA,GAS6,PRKCA,PFN2,PPM1E,DACT1,MYC,PRKCD,DAB2IP,PDE4D,TSHR,HSPA2,GPR161,PDK1,PTPN6,ADCY1,STRADB,WWC1,WNT11,ACVR2B,TLR6,GPLD1,TRIB3,FGR,WFS1,MAP2K6,WWTR1,ERN1,TNFSF15,SMYD3,PKIA |
| 1.812e-02 | -4.01 | EPEND | smart domains | SM00026 | 1 | 1 | 9493 | 172 |
EPDR1 |
| 1.814e-02 | -4.01 | GSE12963_UNINF_VS_ENV_AND_NEF_AND_VPR_DEFICIENT_HIV1_INF_CD4_TCELL_DN | MSigDB lists | GSE12963_UNINF_VS_ENV_AND_NEF_AND_VPR_DEFICIENT_HIV1_INF_CD4_TCELL_DN | 128 | 6 | 17377 | 282 |
CPNE2,GAPDH,TMEM37,SAV1,APBA2,TBC1D8 |
| 1.814e-02 | -4.01 | GSE40274_CTRL_VS_FOXP3_AND_GATA1_TRANSDUCED_ACTIVATED_CD4_TCELL_UP | MSigDB lists | GSE40274_CTRL_VS_FOXP3_AND_GATA1_TRANSDUCED_ACTIVATED_CD4_TCELL_UP | 128 | 6 | 17377 | 282 |
P4HA1,NUMBL,GAS6,TNFRSF17,SMPDL3A,PLEKHG1 |
| 1.814e-02 | -4.01 | positive regulation of cellular catabolic process | biological process | GO:0031331 | 339 | 11 | 17256 | 270 |
LONRF1,TRIB3,DACT1,PLK2,PRKCD,BNIP3L,HK2,BNIP3,CEBPA,DAB2IP,GPLD1 |
| 1.815e-02 | -4.01 | GO_PYRUVATE_METABOLIC_PROCESS | MSigDB lists | GO_PYRUVATE_METABOLIC_PROCESS | 62 | 4 | 17377 | 282 |
GAPDH,ALDOA,OGDHL,HK2 |
| 1.815e-02 | -4.01 | PID_MYC_REPRESS_PATHWAY | MSigDB lists | PID_MYC_REPRESS_PATHWAY | 62 | 4 | 17377 | 282 |
NDRG2,CEBPA,MYC,DDIT3 |
| 1.815e-02 | -4.01 | purine nucleoside monophosphate biosynthetic process | biological process | GO:0009127 | 97 | 5 | 17256 | 270 |
LHPP,GAPDH,ALDOA,OGDHL,HK2 |
| 1.815e-02 | -4.01 | purine ribonucleoside monophosphate biosynthetic process | biological process | GO:0009168 | 97 | 5 | 17256 | 270 |
LHPP,GAPDH,ALDOA,OGDHL,HK2 |
| 1.815e-02 | -4.01 | positive regulation of transporter activity | biological process | GO:0032411 | 97 | 5 | 17256 | 270 |
SGK1,SGK2,HSPA2,PRKCD,EHD3 |
| 1.819e-02 | -4.01 | GO_POSITIVE_REGULATION_OF_DNA_DAMAGE_RESPONSE_SIGNAL_TRANSDUCTION_BY_P53_CLASS_MEDIATOR | MSigDB lists | GO_POSITIVE_REGULATION_OF_DNA_DAMAGE_RESPONSE_SIGNAL_TRANSDUCTION_BY_P53_CLASS_MEDIATOR | 13 | 2 | 17377 | 282 |
MSX1,PMAIP1 |
| 1.819e-02 | -4.01 | GO_EXTRACELLULAR_FIBRIL_ORGANIZATION | MSigDB lists | GO_EXTRACELLULAR_FIBRIL_ORGANIZATION | 13 | 2 | 17377 | 282 |
ADAMTS3,B4GALT7 |
| 1.819e-02 | -4.01 | GO_POSITIVE_REGULATION_OF_CELLULAR_AMINE_METABOLIC_PROCESS | MSigDB lists | GO_POSITIVE_REGULATION_OF_CELLULAR_AMINE_METABOLIC_PROCESS | 13 | 2 | 17377 | 282 |
ABAT,PRKCD |
| 1.819e-02 | -4.01 | WU_HBX_TARGETS_2_DN | MSigDB lists | WU_HBX_TARGETS_2_DN | 13 | 2 | 17377 | 282 |
PMAIP1,PRKCD |
| 1.819e-02 | -4.01 | WU_HBX_TARGETS_3_DN | MSigDB lists | WU_HBX_TARGETS_3_DN | 13 | 2 | 17377 | 282 |
GAS6,PMAIP1 |
| 1.819e-02 | -4.01 | GO_CELL_MIGRATION_IN_HINDBRAIN | MSigDB lists | GO_CELL_MIGRATION_IN_HINDBRAIN | 13 | 2 | 17377 | 282 |
RERE,PLXNA2 |
| 1.823e-02 | -4.00 | cellular response to metal ion | biological process | GO:0071248 | 171 | 7 | 17256 | 270 |
CPNE2,CEBPA,SLC40A1,BNIP3,SCN5A,ADCY1,GPLD1 |
| 1.829e-02 | -4.00 | GSE34156_UNTREATED_VS_6H_TLR1_TLR2_LIGAND_TREATED_MONOCYTE_DN | MSigDB lists | GSE34156_UNTREATED_VS_6H_TLR1_TLR2_LIGAND_TREATED_MONOCYTE_DN | 165 | 7 | 17377 | 282 |
CPNE2,CEBPA,DISP1,LHPP,RAB38,KIF21B,ARRDC4 |
| 1.829e-02 | -4.00 | IL15_UP.V1_DN | MSigDB lists | IL15_UP.V1_DN | 165 | 7 | 17377 | 282 |
PRSS16,TANC2,LGR4,PNRC1,MAP2K6,DACT1,CYB5R2 |
| 1.829e-02 | -4.00 | VERHAAK_GLIOBLASTOMA_PRONEURAL | MSigDB lists | VERHAAK_GLIOBLASTOMA_PRONEURAL | 165 | 7 | 17377 | 282 |
PPM1E,ABAT,RALGPS2,KIF21B,SATB1,PFN2,FHOD3 |
| 1.831e-02 | -4.00 | Kelch_1 | interpro domains | IPR006652 | 63 | 4 | 18492 | 296 |
KLHL31,KLHL3,KLHL23,GAN |
| 1.832e-02 | -4.00 | transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding | molecular function | GO:0001228 | 417 | 13 | 17224 | 278 |
RUNX2,MSX1,SOX21,MYC,EBF4,MAFB,CEBPA,SATB2,OVOL2,DBP,DLX2,BARX1,DDIT3 |
| 1.847e-02 | -3.99 | V$GATA_C | MSigDB lists | V$GATA_C | 244 | 9 | 17377 | 282 |
BDNF,PPM1E,ACVR1,ZHX3,BLVRB,SRGAP1,WNT11,ZNF219,SATB1 |
| 1.848e-02 | -3.99 | adrenal_cortical_carcinoma | COSMIC cancer mutations | adrenal_cortical_carcinoma | 2311 | 50 | 17385 | 281 |
CCDC148,ZHX3,DOCK1,ST14,ARHGEF11,CCDC110,PTPN21,CYP4V2,PLXNA2,KIF5C,ZNF219,HMCN1,TIAM2,MTUS1,TMEM53,MARVELD2,GPR155,EHD3,EBF4,SRGAP1,PRICKLE2,DAB2IP,MYH15,NCEH1,RAB27B,TLN2,MOXD1,DNAH5,GPR161,C3orf67,ZNF391,QSOX1,IL17RD,KLHL3,PTPN6,PPFIA4,WNT11,LHPP,PRDM1,JAM3,ZNF558,NT5DC2,RERE,IFT81,TCF7L1,KIAA0355,HK2,KIAA0513,MYOM2,TANC2 |
| 1.854e-02 | -3.99 | negative regulation of biological process | biological process | GO:0048519 | 5221 | 98 | 17256 | 270 |
ACVR1,DUSP8,LGR4,RASAL2,RECK,C4A,PLXNA2,NDRG2,CEBPA,ITPR2,ABAT,PRKCA,ABHD6,CBLN1,EPCAM,PPM1E,DACT1,DAB2IP,PDE4D,EPHB6,FANK1,HSPA2,PHLDB2,GAPDH,PNRC1,WISP3,PTPN6,BNIP3L,NLGN4X,SATB2,WNT11,ACVR2B,PLEKHA1,SAV1,PLK2,WFS1,RBPMS2,ERN1,WWTR1,ARHGAP28,TMOD2,DLX2,KCTD1,RGS16,RUNX2,NECAB2,MXI1,ZHX3,FBXO4,UBASH3B,ARL2,RASL11B,CHADL,SLX1B,GAS6,OVOL2,TNFRSF10C,ZNF219,SATB1,PFN2,FHOD3,IL17D,RGS17,MYC,PRKCD,RASD2,SRGAP1,BNIP3,STXBP1,BARX1,GPR161,PARP9,EPB41L5,SLC40A1,QSOX1,BDNF,MSX1,NUAK2,EFNA3,WWC1,STRADB,MAFB,SHISA2,PRDM1,TLR6,RERE,GPLD1,CTIF,TRIB3,GNAO1,MAP2K6,HK2,CLMN,SMYD3,B4GALT7,DDIT3,PKIA,PHC1 |
| 1.859e-02 | -3.99 | ABAT (4-aminobutyrate aminotransferase) | protein interactions | 18 | 34 | 3 | 17029 | 283 |
ABAT,LGR4,DSTN |
| 1.864e-02 | -3.98 | positive regulation of biosynthetic process | biological process | GO:0009891 | 1831 | 40 | 17256 | 270 |
RUNX2,ZNF516,ACVR1,LGR4,ARHGEF11,FBXO4,CEBPA,OVOL2,ZNF219,ABHD6,KDM7A,EPCAM,MYC,PRKCD,GTF2F2,EBF4,DAB2IP,TSHR,FANK1,BARX1,GPR161,PARP9,SLC40A1,MSX1,SOX21,WWC1,MAFB,WNT11,SATB2,PXYLP1,TLR6,GPLD1,RERE,DYRK1B,MAP2K6,WWTR1,DLX2,DBP,SMYD3,DDIT3 |
| 1.877e-02 | -3.98 | LINDGREN_BLADDER_CANCER_CLUSTER_2A_DN | MSigDB lists | LINDGREN_BLADDER_CANCER_CLUSTER_2A_DN | 129 | 6 | 17377 | 282 |
SGK1,MAFB,PALLD,STXBP1,BACE1,TBC1D8 |
| 1.877e-02 | -3.98 | CRX_DN.V1_DN | MSigDB lists | CRX_DN.V1_DN | 129 | 6 | 17377 | 282 |
WWC1,ZNF474,CEBPA,PRDM1,JAM3,SMPDL3A |
| 1.878e-02 | -3.97 | tube morphogenesis | biological process | GO:0035239 | 622 | 17 | 17256 | 270 |
EPB41L5,ACVR1,LGR4,ST14,KLHL3,WNT11,PRDM1,ACVR2B,OVOL2,PRKCA,JAM3,GPLD1,MYC,RBPMS2,DACT1,DAB2IP,COBL |
| 1.883e-02 | -3.97 | regulation of cartilage development | biological process | GO:0061035 | 65 | 4 | 17256 | 270 |
CHADL,WNT11,RUNX2,ZNF219 |
| 1.883e-02 | -3.97 | negative regulation of protein polymerization | biological process | GO:0032272 | 65 | 4 | 17256 | 270 |
TMOD2,PFN2,PRKCD,FHOD3 |
| 1.884e-02 | -3.97 | GSE6259_33D1_POS_DC_VS_CD4_TCELL_DN | MSigDB lists | GSE6259_33D1_POS_DC_VS_CD4_TCELL_DN | 166 | 7 | 17377 | 282 |
MAFB,ACSL1,NCEH1,SCAMP1,HEBP1,BLVRB,MTUS1 |
| 1.884e-02 | -3.97 | GSE6269_HEALTHY_VS_STAPH_PNEUMO_INF_PBMC_DN | MSigDB lists | GSE6269_HEALTHY_VS_STAPH_PNEUMO_INF_PBMC_DN | 166 | 7 | 17377 | 282 |
QSOX1,ACSL1,ARHGEF11,BLVRB,ALDOA,CTIF,BNIP3L |
| 1.884e-02 | -3.97 | GO_RECEPTOR_SIGNALING_PROTEIN_ACTIVITY | MSigDB lists | GO_RECEPTOR_SIGNALING_PROTEIN_ACTIVITY | 166 | 7 | 17377 | 282 |
STRADB,MAPK13,ACVR2B,ITPR2,ACVR1,MAP2K6,TIAM2 |
| 1.884e-02 | -3.97 | GSE8685_IL2_ACT_IL2_STARVED_VS_IL21_ACT_IL2_STARVED_CD4_TCELL_UP | MSigDB lists | GSE8685_IL2_ACT_IL2_STARVED_VS_IL21_ACT_IL2_STARVED_CD4_TCELL_UP | 166 | 7 | 17377 | 282 |
EPCAM,FGR,PRKCA,ARRDC4,ABHD4,UBASH3B,GPLD1 |
| 1.885e-02 | -3.97 | adenoma | COSMIC cancer mutations | adenoma | 2923 | 61 | 17385 | 281 |
RUNX2,RASAL2,ST14,ARHGEF11,CYP2J2,PTPN21,SETBP1,KIF5C,ZNF219,PRKCA,HMCN1,TIAM2,FHOD3,MTUS1,NUMBL,RGS17,RALGPS2,KMO,PRKCD,EHD3,ZNF521,SRGAP1,ZDHHC23,EEPD1,TRIM3,PDE4D,NCEH1,RAB27B,TLN2,DNAH5,TSHR,STXBP1,TBC1D8,TMC7,MN1,IL17RD,PHLDB2,KLHL3,KLHL23,SLC39A8,NUAK2,ADCY1,NLGN4X,WNT11,TNS1,ABCC2,SGK2,TLR6,GPLD1,IQCK,TCF7L1,LMLN,ADAMTS3,GNAO1,PLEKHG1,MAPK13,MYOM2,DISP1,IQSEC2,APBA2,KCTD1 |
| 1.887e-02 | -3.97 | GO_CALCIUM_CHANNEL_REGULATOR_ACTIVITY | MSigDB lists | GO_CALCIUM_CHANNEL_REGULATOR_ACTIVITY | 35 | 3 | 17377 | 282 |
SGK1,SGK2,HPCAL4 |
| 1.891e-02 | -3.97 | striated muscle cell development | biological process | GO:0055002 | 134 | 6 | 17256 | 270 |
MYOM2,TMOD2,BVES,SMYD3,MYORG,FHOD3 |
| 1.902e-02 | -3.96 | IGSF1 (immunoglobulin superfamily member 1) | protein interactions | 3547 | 13 | 2 | 17029 | 283 |
ACVR2B,ACVR1 |
| 1.902e-02 | -3.96 | BDKRB2 (bradykinin receptor B2) | protein interactions | 624 | 13 | 2 | 17029 | 283 |
GRK3,PRKCD |
| 1.902e-02 | -3.96 | PARP14 (poly(ADP-ribose) polymerase family member 14) | protein interactions | 54625 | 13 | 2 | 17029 | 283 |
GAN,PARP9 |
| 1.902e-02 | -3.96 | PGAM2 (phosphoglycerate mutase 2) | protein interactions | 5224 | 13 | 2 | 17029 | 283 |
GAPDH,ALDOA |
| 1.902e-02 | -3.96 | CDCP1 (CUB domain containing protein 1) | protein interactions | 64866 | 13 | 2 | 17029 | 283 |
ST14,PRKCD |
| 1.902e-02 | -3.96 | CKMT2 (creatine kinase, mitochondrial 2) | protein interactions | 1160 | 13 | 2 | 17029 | 283 |
ABHD6,ALDOA |
| 1.902e-02 | -3.96 | DBP (D-box binding PAR bZIP transcription factor) | protein interactions | 1628 | 13 | 2 | 17029 | 283 |
CEBPA,DDIT3 |
| 1.904e-02 | -3.96 | Estrogen signaling pathway | KEGG pathways | ko04915 | 98 | 5 | 7161 | 113 |
ITPR2,HSPA2,GNAO1,PRKCD,ADCY1 |
| 1.904e-02 | -3.96 | Estrogen signaling pathway | KEGG pathways | hsa04915 | 98 | 5 | 7161 | 113 |
ITPR2,HSPA2,GNAO1,PRKCD,ADCY1 |
| 1.908e-02 | -3.96 | GO_POSITIVE_REGULATION_OF_KINASE_ACTIVITY | MSigDB lists | GO_POSITIVE_REGULATION_OF_KINASE_ACTIVITY | 462 | 14 | 17377 | 282 |
FGR,ACSL1,MAP2K6,PRKCD,ERN1,ADCY1,STRADB,DAB2IP,WNT11,TNFSF15,ACVR2B,GAS6,TLR6,HSPA2 |
| 1.911e-02 | -3.96 | GO_CELLULAR_HOMEOSTASIS | MSigDB lists | GO_CELLULAR_HOMEOSTASIS | 648 | 18 | 17377 | 282 |
QSOX1,SLC40A1,SLC39A8,ATOX1,ATP6V1E2,ABCC2,ITPR2,GAS6,RAB38,SGK2,CACNB4,WFS1,MYC,ERN1,ALDOA,HK2,SGK1,DDIT3 |
| 1.914e-02 | -3.96 | PID_ENDOTHELIN_PATHWAY | MSigDB lists | PID_ENDOTHELIN_PATHWAY | 63 | 4 | 17377 | 282 |
PRKCA,GNAO1,PRKCD,ADCY1 |
| 1.914e-02 | -3.96 | GO_POSITIVE_REGULATION_OF_DENDRITE_DEVELOPMENT | MSigDB lists | GO_POSITIVE_REGULATION_OF_DENDRITE_DEVELOPMENT | 63 | 4 | 17377 | 282 |
SGK1,NUMBL,DAB2IP,COBL |
| 1.918e-02 | -3.95 | Protein_kinase_ATP_BS | interpro domains | IPR017441 | 378 | 12 | 18492 | 296 |
DYRK1B,FGR,ACVR1,MAP2K6,PLK2,PRKCD,NUAK2,SGK1,MAPK13,SGK2,PRKCA,GRK3 |
| 1.929e-02 | -3.95 | TSP1_rpt_sf | interpro domains | IPR036383 | 64 | 4 | 18492 | 296 |
WISP3,ADAMTS3,HMCN1,ISM1 |
| 1.930e-02 | -3.95 | negative regulation of MAPK cascade | biological process | GO:0043409 | 173 | 7 | 17256 | 270 |
NDRG2,DAB2IP,DUSP8,DACT1,PTPN6,MYC,PRKCD |
| 1.940e-02 | -3.94 | NOTCH_DN.V1_UP | MSigDB lists | NOTCH_DN.V1_UP | 167 | 7 | 17377 | 282 |
MN1,CLMN,TNS1,FKBP9,RUNX2,HPCAL4,EFNA3 |
| 1.940e-02 | -3.94 | GSE37605_FOXP3_FUSION_GFP_VS_IRES_GFP_TREG_C57BL6_DN | MSigDB lists | GSE37605_FOXP3_FUSION_GFP_VS_IRES_GFP_TREG_C57BL6_DN | 167 | 7 | 17377 | 282 |
SGK1,RASL11B,TNS1,FKBP9,GAS6,RASAL2,JAM3 |
| 1.940e-02 | -3.94 | GSE45365_HEALTHY_VS_MCMV_INFECTION_CD11B_DC_IFNAR_KO_UP | MSigDB lists | GSE45365_HEALTHY_VS_MCMV_INFECTION_CD11B_DC_IFNAR_KO_UP | 167 | 7 | 17377 | 282 |
TRIM3,KIF5C,ZNF827,ENAM,DISP1,EPHB6,HPCAL4 |
| 1.940e-02 | -3.94 | GSE16450_CTRL_VS_IFNA_6H_STIM_IMMATURE_NEURON_CELL_LINE_DN | MSigDB lists | GSE16450_CTRL_VS_IFNA_6H_STIM_IMMATURE_NEURON_CELL_LINE_DN | 167 | 7 | 17377 | 282 |
KIAA0513,MXI1,PDE4D,PNRC1,HPCAL4,PLEKHB1,PHC1 |
| 1.942e-02 | -3.94 | ONDER_CDH1_TARGETS_1_UP | MSigDB lists | ONDER_CDH1_TARGETS_1_UP | 130 | 6 | 17377 | 282 |
DBP,ZNF516,PNRC1,PRSS16,PRKCA,ABHD4 |
| 1.946e-02 | -3.94 | intestinal_adenocarcinoma | COSMIC cancer mutations | intestinal_adenocarcinoma | 7391 | 137 | 17385 | 281 |
ARHGAP26,ACVR1,PTPN21,ITPR2,PRKCA,ABHD4,CACNB4,ABHD6,HMCN1,NCS1,CPNE2,FKBP9,DLX6,MARVELD2,TMEM143,TLN2,OR2W3,ZNF391,KLHL23,ABCC2,TNS1,ACVR2B,SGK2,NT5DC2,SPNS1,TCF7L1,PLK2,ERN1,ARHGAP28,TANC2,LONRF1,TMEM63C,SCN5A,RUNX2,ZHX3,BVES,CYP2J2,CYP4V2,SETBP1,CHADL,SLC36A4,TNFRSF10C,DYNC1I1,SATB1,NIPSNAP3B,FHOD3,MTUS1,MYC,SRGAP1,BNIP3,GPR161,EPB41L5,BDNF,IL17RD,QSOX1,SPATA13,PPFIA4,WWC1,STRADB,PRDM1,ARRDC4,B4GALNT3,ADAMTS3,KIAA0355,ISM1,LRRIQ3,EMILIN2,QPCTL,HK2,CLMN,IQSEC2,SMYD3,ZNF516,RASAL2,DOCK1,CCDC110,FAM198B,KIF21B,COLEC10,RADIL,TIAM2,ZNF827,KMO,DACT1,EEPD1,ZNF521,MYH15,DAB2IP,PDE4D,PJA1,TMEM120B,DNAH5,FAM78B,DZANK1,CYB5R2,ADCY1,NLGN4X,WNT11,SATB2,TBC1D16,TRIQK,IQCK,WFS1,WWTR1,PLEKHG1,P4HA1,TNFSF15,KLHL31,COBL,TMEM132C,PRSS16,CCNJL,KIF5C,NEO1,EHD3,ACTA2,PRICKLE2,TRIM3,PARP9,MN1,TMC7,PXN,MPP1,OGDHL,PALLD,TLR6,CTIF,GPLD1,RERE,TRIB3,GNAO1,KIAA0513,ZNF474,THAP10,TNFRSF17,RNF157,PHC1 |
| 1.946e-02 | -3.94 | stomach-carcinoma-intestinal_adenocarcinoma | COSMIC cancer mutations | stomach-carcinoma-intestinal_adenocarcinoma | 7391 | 137 | 17385 | 281 |
ARHGAP26,ACVR1,PTPN21,ITPR2,PRKCA,ABHD4,CACNB4,ABHD6,HMCN1,NCS1,CPNE2,FKBP9,DLX6,MARVELD2,TMEM143,TLN2,OR2W3,ZNF391,KLHL23,ABCC2,TNS1,ACVR2B,SGK2,NT5DC2,SPNS1,TCF7L1,PLK2,ERN1,ARHGAP28,TANC2,LONRF1,TMEM63C,SCN5A,RUNX2,ZHX3,BVES,CYP2J2,CYP4V2,SETBP1,CHADL,SLC36A4,TNFRSF10C,DYNC1I1,SATB1,NIPSNAP3B,FHOD3,MTUS1,MYC,SRGAP1,BNIP3,GPR161,EPB41L5,BDNF,IL17RD,QSOX1,SPATA13,PPFIA4,WWC1,STRADB,PRDM1,ARRDC4,B4GALNT3,ADAMTS3,KIAA0355,ISM1,LRRIQ3,EMILIN2,QPCTL,HK2,CLMN,IQSEC2,SMYD3,ZNF516,RASAL2,DOCK1,CCDC110,FAM198B,KIF21B,COLEC10,RADIL,TIAM2,ZNF827,KMO,DACT1,EEPD1,ZNF521,MYH15,DAB2IP,PDE4D,PJA1,TMEM120B,DNAH5,FAM78B,DZANK1,CYB5R2,ADCY1,NLGN4X,WNT11,SATB2,TBC1D16,TRIQK,IQCK,WFS1,WWTR1,PLEKHG1,P4HA1,TNFSF15,KLHL31,COBL,TMEM132C,PRSS16,CCNJL,KIF5C,NEO1,EHD3,ACTA2,PRICKLE2,TRIM3,PARP9,MN1,TMC7,PXN,MPP1,OGDHL,PALLD,TLR6,CTIF,GPLD1,RERE,TRIB3,GNAO1,KIAA0513,ZNF474,THAP10,TNFRSF17,RNF157,PHC1 |
| 1.950e-02 | -3.94 | GO_CONTRACTILE_FIBER | MSigDB lists | GO_CONTRACTILE_FIBER | 206 | 8 | 17377 | 282 |
SCN5A,ALDOA,ACTA2,TMOD2,MYH15,MYOM2,PALLD,FHOD3 |
| 1.950e-02 | -3.94 | BRUINS_UVC_RESPONSE_VIA_TP53_GROUP_B | MSigDB lists | BRUINS_UVC_RESPONSE_VIA_TP53_GROUP_B | 509 | 15 | 17377 | 282 |
TMEM53,QSOX1,RGS16,TMEM132C,RALGPS2,PMAIP1,FBXO4,MARVELD2,WFS1,RASD2,PRKCD,NUAK2,TRIM3,FAM198B,ABHD4 |
| 1.952e-02 | -3.94 | Kelch | smart domains | SM00612 | 57 | 4 | 9493 | 172 |
KLHL31,KLHL3,KLHL23,GAN |
| 1.952e-02 | -3.94 | GO_ACTIN_BINDING | MSigDB lists | GO_ACTIN_BINDING | 374 | 12 | 17377 | 282 |
KLHL3,DSTN,ALDOA,CLMN,TMOD2,MYH15,TNS1,TLN2,PALLD,PFN2,COBL,FHOD3 |
| 1.955e-02 | -3.93 | Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors | REACTOME pathways | R-HSA-8864260 | 40 | 3 | 10287 | 148 |
KCTD15,MYC,KCTD1 |
| 1.961e-02 | -3.93 | renal absorption | biological process | GO:0070293 | 14 | 2 | 17256 | 270 |
SGK1,KLHL3 |
| 1.961e-02 | -3.93 | positive regulation of endoplasmic reticulum unfolded protein response | biological process | GO:1900103 | 14 | 2 | 17256 | 270 |
DAB2IP,ERN1 |
| 1.961e-02 | -3.93 | positive regulation of DNA damage response, signal transduction by p53 class mediator | biological process | GO:0043517 | 14 | 2 | 17256 | 270 |
MSX1,PMAIP1 |
| 1.961e-02 | -3.93 | regulation of odontogenesis of dentin-containing tooth | biological process | GO:0042487 | 14 | 2 | 17256 | 270 |
ENAM,RUNX2 |
| 1.961e-02 | -3.93 | ATP6V1E1 (ATPase H+ transporting V1 subunit E1) | protein interactions | 529 | 62 | 4 | 17029 | 283 |
ZNF827,TMOD2,ABCC2,ALDOA |
| 1.981e-02 | -3.92 | leukocyte homeostasis | biological process | GO:0001776 | 66 | 4 | 17256 | 270 |
SLC40A1,TNFRSF17,PMAIP1,JAM3 |
| 1.981e-02 | -3.92 | nephron epithelium morphogenesis | biological process | GO:0072088 | 66 | 4 | 17256 | 270 |
WNT11,LGR4,KLHL3,MYC |
| 1.987e-02 | -3.92 | beta-alanine degradation | BIOCYC pathways | HUMAN_BETA-ALA-DEGRADATION-I-PWY | 2 | 1 | 902 | 9 |
ABAT |
| 1.987e-02 | -3.92 | GABA shunt | BIOCYC pathways | META_GLUDEG-I-PWY | 2 | 1 | 902 | 9 |
ABAT |
| 1.989e-02 | -3.92 | Protein-protein interactions at synapses | REACTOME pathways | R-HSA-6794362 | 72 | 4 | 10287 | 148 |
NLGN4X,EPB41L5,APBA2,STXBP1 |
| 1.992e-02 | -3.92 | distal axon | cellular component | GO:0150034 | 261 | 9 | 18223 | 280 |
BLVRB,NDRG2,KIF5C,TMOD2,PALLD,KIF21B,PFN2,COBL,TIAM2 |
| 1.992e-02 | -3.92 | Signalling by NGF | REACTOME pathways | R-HSA-166520 | 477 | 13 | 10287 | 148 |
IL17RD,TRIB3,RASAL2,DUSP8,ARHGEF11,RASGRF2,PRKCD,ADCY1,DAB2IP,MAPK13,ITPR2,PRKCA,TIAM2 |
| 1.997e-02 | -3.91 | response to metal ion | biological process | GO:0010038 | 344 | 11 | 17256 | 270 |
CPNE2,SLC40A1,SCN5A,UROS,SLC30A4,ADCY1,CEBPA,ABCC2,BNIP3,ABAT,GPLD1 |
| 1.997e-02 | -3.91 | GSE7219_UNSTIM_VS_LPS_AND_ANTI_CD40_STIM_DC_DN | MSigDB lists | GSE7219_UNSTIM_VS_LPS_AND_ANTI_CD40_STIM_DC_DN | 168 | 7 | 17377 | 282 |
RGS16,RUNX2,NCEH1,ABHD4,PFN2,SMYD3,ERN1 |
| 2.002e-02 | -3.91 | Rho GTPase binding | molecular function | GO:0017048 | 169 | 7 | 17224 | 278 |
ARHGEF11,DOCK1,RASGRF2,TIAM2,PLEKHG1,SRGAP1,SPATA13 |
| 2.006e-02 | -3.91 | sodium channel regulator activity | molecular function | GO:0017080 | 36 | 3 | 17224 | 278 |
SGK1,SGK2,GPLD1 |
| 2.007e-02 | -3.91 | REACTOME_DOWNSTREAM_SIGNALING_OF_ACTIVATED_FGFR | MSigDB lists | REACTOME_DOWNSTREAM_SIGNALING_OF_ACTIVATED_FGFR | 96 | 5 | 17377 | 282 |
TRIB3,ITPR2,PRKCA,PRKCD,ADCY1 |
| 2.007e-02 | -3.91 | GO_NEGATIVE_REGULATION_OF_INTRACELLULAR_PROTEIN_TRANSPORT | MSigDB lists | GO_NEGATIVE_REGULATION_OF_INTRACELLULAR_PROTEIN_TRANSPORT | 96 | 5 | 17377 | 282 |
DAB2IP,MXI1,GAS6,WWTR1,PKIA |
| 2.007e-02 | -3.91 | REACTOME_SIGNALING_BY_ERBB2 | MSigDB lists | REACTOME_SIGNALING_BY_ERBB2 | 96 | 5 | 17377 | 282 |
TRIB3,ITPR2,PRKCA,PRKCD,ADCY1 |
| 2.008e-02 | -3.91 | BNIP3L (BCL2 interacting protein 3 like) | protein interactions | 665 | 35 | 3 | 17029 | 283 |
BNIP3,KLHL23,BNIP3L |
| 2.008e-02 | -3.91 | SLC1A1 (solute carrier family 1 member 1) | protein interactions | 6505 | 35 | 3 | 17029 | 283 |
NRN1,NUMBL,PRKCA |
| 2.008e-02 | -3.91 | NOS1 (nitric oxide synthase 1) | protein interactions | 4842 | 35 | 3 | 17029 | 283 |
PRKCA,PTPN6,ZDHHC23 |
| 2.009e-02 | -3.91 | muscle system process | biological process | GO:0003012 | 300 | 10 | 17256 | 270 |
SCN5A,PXN,ARHGEF11,MAP2K6,GNAO1,ALDOA,ACTA2,TMOD2,MYOM2,PDE4D |
| 2.009e-02 | -3.91 | GO_NEGATIVE_REGULATION_OF_CELL_CELL_ADHESION | MSigDB lists | GO_NEGATIVE_REGULATION_OF_CELL_CELL_ADHESION | 131 | 6 | 17377 | 282 |
EPB41L5,EPCAM,ABAT,UBASH3B,PTPN6,PRKCD |
| 2.009e-02 | -3.91 | KRAS.LUNG_UP.V1_UP | MSigDB lists | KRAS.LUNG_UP.V1_UP | 131 | 6 | 17377 | 282 |
KIF5C,TTC22,ADAMTS3,CYP2J2,FBXO4,OGDHL |
| 2.019e-02 | -3.90 | cytokine production | biological process | GO:0001816 | 136 | 6 | 17256 | 270 |
INAVA,WNT11,GAS6,TLR6,ADAMTS3,PRKCD |
| 2.026e-02 | -3.90 | GRN (granulin precursor) | protein interactions | 2896 | 94 | 5 | 17029 | 283 |
INAVA,TRIB3,DLX2,SAV1,FAM131C |
| 2.026e-02 | -3.90 | GNAI1 (G protein subunit alpha i1) | protein interactions | 2770 | 94 | 5 | 17029 | 283 |
RGS17,RGS16,TSHR,KLHL3,GNAO1 |
| 2.028e-02 | -3.90 | positive regulation of phosphorylation | biological process | GO:0042327 | 1033 | 25 | 17256 | 270 |
ACSL1,ACVR1,NECAB2,ADCY1,STRADB,WWC1,GAREM1,WNT11,GAS6,ACVR2B,TNFRSF10C,PRKCA,PFN2,TLR6,FGR,MAP2K6,PRKCD,ERN1,INAVA,TNFSF15,DAB2IP,EPHB6,SMYD3,HSPA2,PARP9 |
| 2.028e-02 | -3.90 | ZHOU_INFLAMMATORY_RESPONSE_FIMA_DN | MSigDB lists | ZHOU_INFLAMMATORY_RESPONSE_FIMA_DN | 248 | 9 | 17377 | 282 |
CCDC148,ZNF395,KLHL23,EHD3,NDRG2,CEBPA,DNAH5,VGLL4,TLR6 |
| 2.028e-02 | -3.90 | V$BACH1_01 | MSigDB lists | V$BACH1_01 | 248 | 9 | 17377 | 282 |
ZNF827,GAPDH,ALDOA,NDRG2,STRADB,SGK1,BNIP3,ABHD4,DDIT3 |
| 2.030e-02 | -3.90 | TSP1_rpt | interpro domains | IPR000884 | 65 | 4 | 18492 | 296 |
WISP3,ADAMTS3,HMCN1,ISM1 |
| 2.035e-02 | -3.89 | GO_MULTIVESICULAR_BODY | MSigDB lists | GO_MULTIVESICULAR_BODY | 36 | 3 | 17377 | 282 |
SLC40A1,RAB27B,BACE1 |
| 2.035e-02 | -3.89 | ZHAN_MULTIPLE_MYELOMA_MF_DN | MSigDB lists | ZHAN_MULTIPLE_MYELOMA_MF_DN | 36 | 3 | 17377 | 282 |
PRKCA,MOXD1,CCDC110 |
| 2.041e-02 | -3.89 | limb development | biological process | GO:0060173 | 175 | 7 | 17256 | 270 |
B9D1,MSX1,RUNX2,ZNF219,RECK,DLX6,PLXNA2 |
| 2.041e-02 | -3.89 | appendage development | biological process | GO:0048736 | 175 | 7 | 17256 | 270 |
B9D1,MSX1,RUNX2,ZNF219,RECK,DLX6,PLXNA2 |
| 2.043e-02 | -3.89 | metencephalon development | biological process | GO:0022037 | 100 | 5 | 17256 | 270 |
NLGN4X,SCN5A,ABAT,CBLN1,RERE |
| 2.045e-02 | -3.89 | GO_CELL_PROJECTION_ORGANIZATION | MSigDB lists | GO_CELL_PROJECTION_ORGANIZATION | 847 | 22 | 17377 | 282 |
B9D1,BDNF,ADCY1,SPATA13,PLXNA2,EFNA3,KIF5C,PLEKHA1,JAM3,NEO1,RERE,IFT81,NUMBL,GNAO1,EHD3,WWTR1,CLMN,SGK1,DAB2IP,STXBP1,DNAH5,COBL |
| 2.047e-02 | -3.89 | RasGAP_CS | interpro domains | IPR023152 | 14 | 2 | 18492 | 296 |
DAB2IP,RASAL2 |
| 2.056e-02 | -3.88 | Platelet activation, signaling and aggregation | REACTOME pathways | R-HSA-76002 | 282 | 9 | 10287 | 148 |
QSOX1,PTPN6,ALDOA,PRKCD,GAS6,ITPR2,PRKCA,RAB27B,ABHD6 |
| 2.063e-02 | -3.88 | KUMAR_TARGETS_OF_MLL_AF9_FUSION | MSigDB lists | KUMAR_TARGETS_OF_MLL_AF9_FUSION | 377 | 12 | 17377 | 282 |
FKBP9,GAPDH,PDK1,RALGPS2,SLC30A4,RECK,HK2,SPATA13,DAB2IP,LHPP,PRKCA,SATB1 |
| 2.068e-02 | -3.88 | DYNLL2 (dynein light chain LC8-type 2) | protein interactions | 140735 | 63 | 4 | 17029 | 283 |
WWC1,DZANK1,THAP10,DYNC1I1 |
| 2.071e-02 | -3.88 | WW | pfam domains | PF00397 | 37 | 3 | 17054 | 271 |
WWC1,SAV1,WWTR1 |
| 2.075e-02 | -3.88 | skin-hand-malignant_melanoma | COSMIC cancer mutations | skin-hand-malignant_melanoma | 170 | 7 | 17385 | 281 |
STRADB,THAP10,KIF21B,DNAH5,ARHGEF11,EMILIN2,PGBD5 |
| 2.076e-02 | -3.87 | V$OCT1_B | MSigDB lists | V$OCT1_B | 249 | 9 | 17377 | 282 |
BDNF,MAP2K6,PLXNA2,TMOD2,SATB2,PRDM1,PDE4D,DNAH5,HPCAL4 |
| 2.076e-02 | -3.87 | STK33_DN | MSigDB lists | STK33_DN | 249 | 9 | 17377 | 282 |
IL17D,RGS16,OGDHL,ZDHHC23,TMEM143,SHISA2,SATB2,TANC2,NEO1 |
| 2.077e-02 | -3.87 | GO_MESENCHYMAL_CELL_DIFFERENTIATION | MSigDB lists | GO_MESENCHYMAL_CELL_DIFFERENTIATION | 132 | 6 | 17377 | 282 |
EPB41L5,WNT11,MSX1,ACVR1,OVOL2,WWTR1 |
| 2.077e-02 | -3.87 | SMID_BREAST_CANCER_ERBB2_UP | MSigDB lists | SMID_BREAST_CANCER_ERBB2_UP | 132 | 6 | 17377 | 282 |
TRIM3,ABCC2,ACSL1,KMO,BIK,EFNA3 |
| 2.082e-02 | -3.87 | ventricular septum development | biological process | GO:0003281 | 67 | 4 | 17256 | 270 |
WNT11,PRDM1,ACVR1,SAV1 |
| 2.082e-02 | -3.87 | pyruvate metabolic process | biological process | GO:0006090 | 67 | 4 | 17256 | 270 |
GAPDH,ALDOA,OGDHL,HK2 |
| 2.082e-02 | -3.87 | nephron morphogenesis | biological process | GO:0072028 | 67 | 4 | 17256 | 270 |
WNT11,LGR4,KLHL3,MYC |
| 2.082e-02 | -3.87 | DNA Damage Response (only ATM dependent) | WikiPathways | WP710 | 114 | 6 | 5312 | 101 |
WNT11,TCF7L1,PDK1,PMAIP1,MYC,BIK |
| 2.089e-02 | -3.87 | WINZEN_DEGRADED_VIA_KHSRP | MSigDB lists | WINZEN_DEGRADED_VIA_KHSRP | 97 | 5 | 17377 | 282 |
TMC7,BDNF,PMAIP1,SMPDL3A,PKIA |
| 2.089e-02 | -3.87 | GTGTTGA,MIR-505 | MSigDB lists | GTGTTGA,MIR-505 | 97 | 5 | 17377 | 282 |
ARHGAP26,MAFB,KIAA0408,MXI1,PDE4D |
| 2.100e-02 | -3.86 | REACTOME_METABOLISM_OF_PORPHYRINS | MSigDB lists | REACTOME_METABOLISM_OF_PORPHYRINS | 14 | 2 | 17377 | 282 |
UROS,BLVRB |
| 2.100e-02 | -3.86 | GO_LINOLEIC_ACID_METABOLIC_PROCESS | MSigDB lists | GO_LINOLEIC_ACID_METABOLIC_PROCESS | 14 | 2 | 17377 | 282 |
ACSL1,CYP2J2 |
| 2.100e-02 | -3.86 | GO_COMPACT_MYELIN | MSigDB lists | GO_COMPACT_MYELIN | 14 | 2 | 17377 | 282 |
JAM3,MARVELD2 |
| 2.100e-02 | -3.86 | TIAN_BHLHA15_TARGETS | MSigDB lists | TIAN_BHLHA15_TARGETS | 14 | 2 | 17377 | 282 |
C2orf88,DISP1 |
| 2.100e-02 | -3.86 | ABDULRAHMAN_KIDNEY_CANCER_VHL_DN | MSigDB lists | ABDULRAHMAN_KIDNEY_CANCER_VHL_DN | 14 | 2 | 17377 | 282 |
ACTA2,PALLD |
| 2.100e-02 | -3.86 | ZAIDI_OSTEOBLAST_TRANSCRIPTION_FACTORS | MSigDB lists | ZAIDI_OSTEOBLAST_TRANSCRIPTION_FACTORS | 14 | 2 | 17377 | 282 |
MSX1,RUNX2 |
| 2.100e-02 | -3.86 | GO_INTRINSIC_COMPONENT_OF_THE_CYTOPLASMIC_SIDE_OF_THE_PLASMA_MEMBRANE | MSigDB lists | GO_INTRINSIC_COMPONENT_OF_THE_CYTOPLASMIC_SIDE_OF_THE_PLASMA_MEMBRANE | 14 | 2 | 17377 | 282 |
DAB2IP,RASAL2 |
| 2.100e-02 | -3.86 | GO_ZYMOGEN_GRANULE | MSigDB lists | GO_ZYMOGEN_GRANULE | 14 | 2 | 17377 | 282 |
SCAMP1,RAB27B |
| 2.105e-02 | -3.86 | VERHAAK_GLIOBLASTOMA_MESENCHYMAL | MSigDB lists | VERHAAK_GLIOBLASTOMA_MESENCHYMAL | 209 | 8 | 17377 | 282 |
ACSL1,RUNX2,ST14,PTPN6,BLVRB,WWTR1,MAFB,MAPK13 |
| 2.110e-02 | -3.86 | SIPA1L1 (signal induced proliferation associated 1 like 1) | protein interactions | 26037 | 95 | 5 | 17029 | 283 |
DYRK1B,PHLDB2,RALGPS2,RASAL2,TANC2 |
| 2.110e-02 | -3.86 | PPM1H (protein phosphatase, Mg2+/Mn2+ dependent 1H) | protein interactions | 57460 | 95 | 5 | 17029 | 283 |
PHLDB2,RALGPS2,SCAMP1,RASAL2,TANC2 |
| 2.116e-02 | -3.86 | GSE22611_NOD2_TRANSDUCED_VS_CTRL_HEK293T_STIMULATED_WITH_MDP_2H_UP | MSigDB lists | GSE22611_NOD2_TRANSDUCED_VS_CTRL_HEK293T_STIMULATED_WITH_MDP_2H_UP | 170 | 7 | 17377 | 282 |
SGK1,SPNS1,PXN,RNF122,PFN2,GNAO1,PTPN6 |
| 2.116e-02 | -3.86 | SH3_domain | interpro domains | IPR001452 | 212 | 8 | 18492 | 296 |
ARHGAP26,FGR,DOCK1,MPP1,UBASH3B,SPATA13,SRGAP1,CACNB4 |
| 2.122e-02 | -3.85 | PID_LYSOPHOSPHOLIPID_PATHWAY | MSigDB lists | PID_LYSOPHOSPHOLIPID_PATHWAY | 65 | 4 | 17377 | 282 |
PXN,GNAO1,PRKCD,ADCY1 |
| 2.122e-02 | -3.85 | GO_MONOSACCHARIDE_BINDING | MSigDB lists | GO_MONOSACCHARIDE_BINDING | 65 | 4 | 17377 | 282 |
P4HA1,COLEC10,ALDOA,HK2 |
| 2.122e-02 | -3.85 | RIGGINS_TAMOXIFEN_RESISTANCE_UP | MSigDB lists | RIGGINS_TAMOXIFEN_RESISTANCE_UP | 65 | 4 | 17377 | 282 |
ARHGAP26,FGR,PFN2,ADCY1 |
| 2.124e-02 | -3.85 | kinase activity | molecular function | GO:0016301 | 855 | 22 | 17224 | 278 |
ACVR1,PDK1,MPP1,NUAK2,EFNA3,STRADB,ACVR2B,PRKCA,SGK2,GRK3,DYRK1B,TRIB3,FGR,PLK2,RPS6KL1,MAP2K6,PRKCD,ERN1,HK2,SGK1,MAPK13,EPHB6 |
| 2.135e-02 | -3.85 | NADH metabolic process | biological process | GO:0006734 | 38 | 3 | 17256 | 270 |
GAPDH,ALDOA,HK2 |
| 2.138e-02 | -3.85 | intracellular | cellular component | GO:0005622 | 14533 | 237 | 18223 | 280 |
ARHGAP26,CCDC126,ACSL1,DUSP8,HEBP1,LSM11,PTPN21,ALG1L,NDRG2,CEBPA,ITPR2,ABAT,PRKCA,CACNB4,ABHD6,ABHD4,HMCN1,NCS1,EPDR1,CPNE2,FKBP9,PPM1E,PMAIP1,DLX6,MARVELD2,TMEM143,EPHB6,TLN2,TSHR,FANK1,ZNF391,TBC1D8,PGBD5,SMIM20,PNRC1,KLHL23,KLHL3,WISP3,EXOC6B,DSTN,ATOX1,CAPN5,BNIP3L,SLC25A28,TNS1,ACVR2B,PLEKHA1,SGK2,SAV1,GRK3,PLEKHB1,SPNS1,DYRK1B,TCF7L1,PLK2,RASGRF2,ERN1,ALDOA,ARHGAP28,MAPK13,TMOD2,DLX2,APBA2,LONRF1,GPR63,SCN5A,RGS16,RUNX2,ZNF395,SCART1,ZHX3,CYP2J2,FBXO4,UBASH3B,CYP4V2,ATP6V1E2,SETBP1,SLC36A4,HERC6,SATB1,DYNC1I1,PFN2,HPCAL4,NIPSNAP3B,MYORG,FHOD3,MTUS1,NUMBL,SLC30A4,RALGPS2,MYC,ZIC5,SRGAP1,EBF4,GAN,INAVA,BNIP3,MOXD1,NCEH1,VGLL4,STXBP1,BARX1,GPR161,EPB41L5,ENAM,BDNF,QSOX1,IL17RD,B3GLCT,SPATA13,PPFIA4,WWC1,MAFB,STRADB,SHISA2,PRDM1,LHPP,ARRDC4,B4GALNT3,ZNF558,QPCTL,HK2,CLMN,IQSEC2,RNF122,SMYD3,ZNF516,SCAMP1,RASAL2,DOCK1,C4A,CCDC110,RHPN2,FAM198B,KIF21B,COLEC10,RADIL,TIAM2,TMEM53,ZNF827,KMO,DACT1,RPS6KL1,ZDHHC23,ZNF521,MAP7,DAB2IP,MYH15,PDE4D,PJA1,RAB27B,DNAH5,TMEM120B,HSPA2,PHLDB2,GAPDH,UROS,PDK1,SOX21,PTPN6,CYB5R2,SFXN4,ADCY1,WNT11,SATB2,PXYLP1,RAB38,TBC1D16,TRIQK,JAM3,CENPV,IFT81,LMLN,ZNF697,RBPMS2,WFS1,WWTR1,PLEKHG1,P4HA1,TNFSF15,DBP,KLHL31,COBL,KCTD1,NECAB2,MXI1,PRSS16,ARHGEF11,BACE1,BLVRB,BIK,CCNJL,ARL2,KIF5C,SLX1B,GAS6,OVOL2,ZNF219,NEO1,KDM7A,RGS17,GPR155,PRKCD,EHD3,GTF2F2,ACTA2,SGK1,PRICKLE2,TRIM3,PARP9,B9D1,SLC40A1,LZTS3,PXN,MSX1,MPP1,CCDC184,NUAK2,OGDHL,EXOG,PALLD,TLR6,RERE,GPLD1,CTIF,TRIB3,FGR,FMO4,MAP2K6,GNAO1,KIAA0513,MYOM2,RNF157,B4GALT7,DDIT3,PKIA,PHC1 |
| 2.140e-02 | -3.84 | Melanogenesis | KEGG pathways | ko04916 | 101 | 5 | 7161 | 113 |
TCF7L1,WNT11,PRKCA,GNAO1,ADCY1 |
| 2.140e-02 | -3.84 | HIF-1 signaling pathway | KEGG pathways | hsa04066 | 101 | 5 | 7161 | 113 |
GAPDH,PDK1,PRKCA,ALDOA,HK2 |
| 2.140e-02 | -3.84 | Melanogenesis | KEGG pathways | hsa04916 | 101 | 5 | 7161 | 113 |
TCF7L1,WNT11,PRKCA,GNAO1,ADCY1 |
| 2.146e-02 | -3.84 | head development | biological process | GO:0060322 | 731 | 19 | 17256 | 270 |
SCN5A,MSX1,ADCY1,PLXNA2,NLGN4X,NDRG2,MAFB,SATB2,PLEKHA1,ABAT,CBLN1,RERE,KDM7A,NUMBL,GNAO1,DLX6,BNIP3,DAB2IP,DLX2 |
| 2.146e-02 | -3.84 | REACTOME_NGF_SIGNALLING_VIA_TRKA_FROM_THE_PLASMA_MEMBRANE | MSigDB lists | REACTOME_NGF_SIGNALLING_VIA_TRKA_FROM_THE_PLASMA_MEMBRANE | 133 | 6 | 17377 | 282 |
TRIB3,MAPK13,ITPR2,PRKCA,PRKCD,ADCY1 |
| 2.146e-02 | -3.84 | V$AHRARNT_01 | MSigDB lists | V$AHRARNT_01 | 133 | 6 | 17377 | 282 |
SGK1,TMEM53,BDNF,MXI1,GNAO1,HK2 |
| 2.156e-02 | -3.84 | positive regulation of apoptotic signaling pathway | biological process | GO:2001235 | 177 | 7 | 17256 | 270 |
DAB2IP,BNIP3,MSX1,PMAIP1,PRKCD,DDIT3,BIK |
| 2.157e-02 | -3.84 | calcium channel regulator activity | molecular function | GO:0005246 | 37 | 3 | 17224 | 278 |
SGK1,SGK2,HPCAL4 |
| 2.159e-02 | -3.84 | programmed cell death | biological process | GO:0012501 | 1039 | 25 | 17256 | 270 |
GAPDH,PDK1,ST14,DOCK1,PTPN6,BIK,BNIP3L,NUAK2,GAS6,TNFRSF10C,PRKCA,SAV1,SATB1,TRIB3,PMAIP1,MAP2K6,MYC,PRKCD,ERN1,HK2,SGK1,TNFSF15,DAB2IP,BNIP3,DDIT3 |
| 2.159e-02 | -3.84 | V$SRF_Q4 | MSigDB lists | V$SRF_Q4 | 210 | 8 | 17377 | 282 |
SGK1,MSX1,KLHL3,DSTN,MAP2K6,RASD2,EMILIN2,RERE |
| 2.159e-02 | -3.84 | GO_REGULATION_OF_PROTEIN_STABILITY | MSigDB lists | GO_REGULATION_OF_PROTEIN_STABILITY | 210 | 8 | 17377 | 282 |
MSX1,GAPDH,DACT1,WFS1,PRKCD,SAV1,PFN2,STXBP1 |
| 2.159e-02 | -3.84 | AAGCAAT,MIR-137 | MSigDB lists | AAGCAAT,MIR-137 | 210 | 8 | 17377 | 282 |
PPM1E,RUNX2,DUSP8,ADCY1,PRDM1,ABHD6,SATB1,HMCN1 |
| 2.159e-02 | -3.84 | COLDREN_GEFITINIB_RESISTANCE_DN | MSigDB lists | COLDREN_GEFITINIB_RESISTANCE_DN | 210 | 8 | 17377 | 282 |
MAPK13,TTC22,OVOL2,RAB38,ST14,CYP2J2,PRKCD,BIK |
| 2.160e-02 | -3.83 | Apoptosis | KEGG pathways | hsa04210 | 138 | 6 | 7161 | 113 |
DAB2IP,ITPR2,TNFRSF10C,PMAIP1,ERN1,DDIT3 |
| 2.160e-02 | -3.83 | Apoptosis | KEGG pathways | ko04210 | 138 | 6 | 7161 | 113 |
DAB2IP,ITPR2,TNFRSF10C,PMAIP1,ERN1,DDIT3 |
| 2.162e-02 | -3.83 | Regulation of KIT signaling | REACTOME pathways | R-HSA-1433559 | 16 | 2 | 10287 | 148 |
PRKCA,PTPN6 |
| 2.165e-02 | -3.83 | intrinsic component of the cytoplasmic side of the plasma membrane | cellular component | GO:0031235 | 15 | 2 | 18223 | 280 |
DAB2IP,RASAL2 |
| 2.169e-02 | -3.83 | SH3-like_dom_sf | interpro domains | IPR036028 | 213 | 8 | 18492 | 296 |
ARHGAP26,FGR,DOCK1,MPP1,UBASH3B,SPATA13,SRGAP1,CACNB4 |
| 2.170e-02 | -3.83 | RNA polymerase II regulatory region sequence-specific DNA binding | molecular function | GO:0000977 | 661 | 18 | 17224 | 278 |
RUNX2,MSX1,MXI1,ZNF395,ZHX3,SOX21,MAFB,CEBPA,SATB2,PRDM1,ZNF219,SATB1,MYC,DLX2,DBP,SMYD3,BARX1,DDIT3 |
| 2.173e-02 | -3.83 | KANG_IMMORTALIZED_BY_TERT_DN | MSigDB lists | KANG_IMMORTALIZED_BY_TERT_DN | 98 | 5 | 17377 | 282 |
MAFB,PDE4D,ADAMTS3,DLX6,EFNA3 |
| 2.173e-02 | -3.83 | GO_OXIDOREDUCTION_COENZYME_METABOLIC_PROCESS | MSigDB lists | GO_OXIDOREDUCTION_COENZYME_METABOLIC_PROCESS | 98 | 5 | 17377 | 282 |
GAPDH,KMO,ALDOA,OGDHL,HK2 |
| 2.173e-02 | -3.83 | GO_RENAL_SYSTEM_PROCESS | MSigDB lists | GO_RENAL_SYSTEM_PROCESS | 98 | 5 | 17377 | 282 |
SGK1,GAS6,KLHL3,WFS1,ADCY1 |
| 2.176e-02 | -3.83 | GSE30971_CTRL_VS_LPS_STIM_MACROPHAGE_WBP7_KO_2H_UP | MSigDB lists | GSE30971_CTRL_VS_LPS_STIM_MACROPHAGE_WBP7_KO_2H_UP | 171 | 7 | 17377 | 282 |
MAP7,ATP6V1E2,RGS16,TNFSF15,ACSL1,SAV1,SMPDL3A |
| 2.176e-02 | -3.83 | NAGASHIMA_NRG1_SIGNALING_UP | MSigDB lists | NAGASHIMA_NRG1_SIGNALING_UP | 171 | 7 | 17377 | 282 |
SGK1,DLX2,DUSP8,PALLD,PMAIP1,MYC,DDIT3 |
| 2.176e-02 | -3.83 | GSE3565_CTRL_VS_LPS_INJECTED_DUSP1_KO_SPLENOCYTES_UP | MSigDB lists | GSE3565_CTRL_VS_LPS_INJECTED_DUSP1_KO_SPLENOCYTES_UP | 171 | 7 | 17377 | 282 |
KIF5C,PRDM1,RUNX2,SMYD3,DSTN,SLC39A8,ERN1 |
| 2.176e-02 | -3.83 | GSE3920_UNTREATED_VS_IFNG_TREATED_FIBROBLAST_DN | MSigDB lists | GSE3920_UNTREATED_VS_IFNG_TREATED_FIBROBLAST_DN | 171 | 7 | 17377 | 282 |
KIF5C,DISP1,SATB1,ZHX3,KLHL3,EXOC6B,BIK |
| 2.177e-02 | -3.83 | POTEF (POTE ankyrin domain family member F) | protein interactions | 728378 | 64 | 4 | 17029 | 283 |
MAPK13,LGR4,TSHR,GAN |
| 2.185e-02 | -3.82 | renal tubule morphogenesis | biological process | GO:0061333 | 68 | 4 | 17256 | 270 |
WNT11,LGR4,KLHL3,MYC |
| 2.185e-02 | -3.82 | negative regulation of wound healing | biological process | GO:0061045 | 68 | 4 | 17256 | 270 |
PHLDB2,ABAT,UBASH3B,PRKCD |
| 2.187e-02 | -3.82 | Integration of energy metabolism | REACTOME pathways | R-HSA-163685 | 111 | 5 | 10287 | 148 |
ARL2,ITPR2,PRKCA,STXBP1,ADCY1 |
| 2.188e-02 | -3.82 | BACK | smart domains | SM00875 | 59 | 4 | 9493 | 172 |
KLHL31,KLHL3,KLHL23,GAN |
| 2.188e-02 | -3.82 | MODULE_512 | MSigDB lists | MODULE_512 | 37 | 3 | 17377 | 282 |
ACTA2,MYOM2,ALDOA |
| 2.188e-02 | -3.82 | GENTILE_UV_RESPONSE_CLUSTER_D5 | MSigDB lists | GENTILE_UV_RESPONSE_CLUSTER_D5 | 37 | 3 | 17377 | 282 |
DLX2,ZHX3,DDIT3 |
| 2.188e-02 | -3.82 | BIOCARTA_PAR1_PATHWAY | MSigDB lists | BIOCARTA_PAR1_PATHWAY | 37 | 3 | 17377 | 282 |
PRKCA,ARHGEF11,ADCY1 |
| 2.188e-02 | -3.82 | GNF2_RAB3A | MSigDB lists | GNF2_RAB3A | 37 | 3 | 17377 | 282 |
KIF5C,STXBP1,EHD3 |
| 2.189e-02 | -3.82 | GO_ACTIN_FILAMENT_BASED_PROCESS | MSigDB lists | GO_ACTIN_FILAMENT_BASED_PROCESS | 425 | 13 | 17377 | 282 |
ARHGAP26,EPB41L5,SCN5A,ARHGEF11,DSTN,ALDOA,NUAK2,TMOD2,PALLD,IQSEC2,PFN2,COBL,FHOD3 |
| 2.195e-02 | -3.82 | CREB3L2 (cAMP responsive element binding protein 3 like 2) | protein interactions | 64764 | 14 | 2 | 17029 | 283 |
RGS16,PXN |
| 2.195e-02 | -3.82 | HNF4G (hepatocyte nuclear factor 4 gamma) | protein interactions | 3174 | 14 | 2 | 17029 | 283 |
GAPDH,PNRC1 |
| 2.195e-02 | -3.82 | ADRA2A (adrenoceptor alpha 2A) | protein interactions | 150 | 14 | 2 | 17029 | 283 |
GNAO1,PRKCD |
| 2.195e-02 | -3.82 | MNT (MAX network transcriptional repressor) | protein interactions | 4335 | 14 | 2 | 17029 | 283 |
CEBPA,MYC |
| 2.195e-02 | -3.82 | HOXC8 (homeobox C8) | protein interactions | 3224 | 14 | 2 | 17029 | 283 |
MSX1,DLX2 |
| 2.195e-02 | -3.82 | GABBR1 (gamma-aminobutyric acid type B receptor subunit 1) | protein interactions | 2550 | 14 | 2 | 17029 | 283 |
GNAO1,DDIT3 |
| 2.199e-02 | -3.82 | bone-tibia-Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour | COSMIC cancer mutations | bone-tibia-Ewings_sarcoma-peripheral_primitive_neuroectodermal_tumour | 661 | 18 | 17385 | 281 |
EPB41L5,SCN5A,TMEM63C,RASAL2,ZHX3,DOCK1,TNS1,SAV1,MTUS1,FGR,RPS6KL1,MAP2K6,WWTR1,PLEKHG1,TRIM3,TNFSF15,GPR161,PARP9 |
| 2.205e-02 | -3.81 | nucleotide catabolic process | biological process | GO:0009166 | 102 | 5 | 17256 | 270 |
PDE4D,GAPDH,ALDOA,OGDHL,HK2 |
| 2.205e-02 | -3.81 | renal system process | biological process | GO:0003014 | 102 | 5 | 17256 | 270 |
SGK1,GAS6,KLHL3,WFS1,ADCY1 |
| 2.210e-02 | -3.81 | SMID_BREAST_CANCER_BASAL_UP | MSigDB lists | SMID_BREAST_CANCER_BASAL_UP | 611 | 17 | 17377 | 282 |
PRSS16,PDK1,CYB5R2,NDRG2,PRKCA,DYNC1I1,PFN2,NT5DC2,PLEKHB1,TCF7L1,PPM1E,MYC,WWTR1,APBA2,BARX1,GPR161,PGBD5 |
| 2.216e-02 | -3.81 | DCTN1 (dynactin subunit 1) | protein interactions | 1639 | 246 | 9 | 17029 | 283 |
LGR4,MAP2K6,MAP7,INAVA,WWC1,ACTA2,KIAA0408,DYNC1I1,MTUS1 |
| 2.222e-02 | -3.81 | V$CEBP_01 | MSigDB lists | V$CEBP_01 | 252 | 9 | 17377 | 282 |
DZANK1,ENAM,PPM1E,KIAA0355,OVOL2,PRDM1,PALLD,ARRDC4,NEO1 |
| 2.225e-02 | -3.81 | RAS_GTPASE_ACTIV_1 | prosite domains | PS00509 | 14 | 2 | 12060 | 202 |
DAB2IP,RASAL2 |
| 2.228e-02 | -3.80 | GO_KINASE_ACTIVITY | MSigDB lists | GO_KINASE_ACTIVITY | 805 | 21 | 17377 | 282 |
ACVR1,PDK1,MPP1,NUAK2,EFNA3,STRADB,ACVR2B,PRKCA,SGK2,DYRK1B,TRIB3,FGR,MAP2K6,RPS6KL1,PLK2,ERN1,PRKCD,HK2,SGK1,MAPK13,EPHB6 |
| 2.231e-02 | -3.80 | SHAFFER_IRF4_TARGETS_IN_PLASMA_CELL_VS_MATURE_B_LYMPHOCYTE | MSigDB lists | SHAFFER_IRF4_TARGETS_IN_PLASMA_CELL_VS_MATURE_B_LYMPHOCYTE | 66 | 4 | 17377 | 282 |
PRDM1,PDK1,TNFRSF17,DDIT3 |
| 2.231e-02 | -3.80 | GO_REGULATION_OF_MEMBRANE_PERMEABILITY | MSigDB lists | GO_REGULATION_OF_MEMBRANE_PERMEABILITY | 66 | 4 | 17377 | 282 |
BNIP3,PMAIP1,HK2,BNIP3L |
| 2.231e-02 | -3.80 | GO_CELLULAR_RESPONSE_TO_DRUG | MSigDB lists | GO_CELLULAR_RESPONSE_TO_DRUG | 66 | 4 | 17377 | 282 |
PPM1E,GAS6,MYC,GPLD1 |
| 2.231e-02 | -3.80 | YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_1 | MSigDB lists | YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_1 | 66 | 4 | 17377 | 282 |
ITPR2,HSPA2,CFHR1,DDIT3 |
| 2.238e-02 | -3.80 | GSE17974_CTRL_VS_ACT_IL4_AND_ANTI_IL12_72H_CD4_TCELL_UP | MSigDB lists | GSE17974_CTRL_VS_ACT_IL4_AND_ANTI_IL12_72H_CD4_TCELL_UP | 172 | 7 | 17377 | 282 |
SGK1,PLEKHA1,HERC6,EXOG,DNAH5,UBASH3B,MTUS1 |
| 2.239e-02 | -3.80 | neuron projection | cellular component | GO:0043005 | 1222 | 28 | 18223 | 280 |
BDNF,NECAB2,MPP1,BACE1,C4A,BLVRB,NLGN4X,KIF5C,NDRG2,ABAT,KIF21B,OR11H4,PALLD,PFN2,TIAM2,NCS1,RGS17,PLK2,WFS1,GNAO1,TRIM3,DAB2IP,BNIP3,TMOD2,EPHB6,APBA2,STXBP1,COBL |
| 2.239e-02 | -3.80 | cell migration in hindbrain | biological process | GO:0021535 | 15 | 2 | 17256 | 270 |
RERE,PLXNA2 |
| 2.239e-02 | -3.80 | cell migration involved in gastrulation | biological process | GO:0042074 | 15 | 2 | 17256 | 270 |
EPB41L5,WNT11 |
| 2.239e-02 | -3.80 | positive regulation of neurotransmitter secretion | biological process | GO:0001956 | 15 | 2 | 17256 | 270 |
KMO,STXBP1 |
| 2.255e-02 | -3.79 | positive regulation of protein phosphorylation | biological process | GO:0001934 | 991 | 24 | 17256 | 270 |
ACSL1,ACVR1,NECAB2,ADCY1,STRADB,WWC1,GAREM1,WNT11,GAS6,ACVR2B,TNFRSF10C,PRKCA,PFN2,TLR6,MAP2K6,PRKCD,ERN1,INAVA,TNFSF15,DAB2IP,EPHB6,SMYD3,HSPA2,PARP9 |
| 2.258e-02 | -3.79 | RNA polymerase II regulatory region DNA binding | molecular function | GO:0001012 | 664 | 18 | 17224 | 278 |
RUNX2,MSX1,MXI1,ZNF395,ZHX3,SOX21,MAFB,CEBPA,SATB2,PRDM1,ZNF219,SATB1,MYC,DLX2,DBP,SMYD3,BARX1,DDIT3 |
| 2.259e-02 | -3.79 | BENPORATH_ES_CORE_NINE_CORRELATED | MSigDB lists | BENPORATH_ES_CORE_NINE_CORRELATED | 99 | 5 | 17377 | 282 |
TCF7L1,PNRC1,VGLL4,MYC,WWTR1 |
| 2.259e-02 | -3.79 | GO_METENCEPHALON_DEVELOPMENT | MSigDB lists | GO_METENCEPHALON_DEVELOPMENT | 99 | 5 | 17377 | 282 |
NLGN4X,SCN5A,ABAT,CBLN1,RERE |
| 2.260e-02 | -3.79 | AAAYRNCTG_UNKNOWN | MSigDB lists | AAAYRNCTG_UNKNOWN | 338 | 11 | 17377 | 282 |
RGS17,SCN5A,ACVR1,PXN,KLHL3,SOX21,ZNF521,TNS1,COLEC10,PFN2,DYNC1I1 |
| 2.266e-02 | -3.79 | regulation of protein complex assembly | biological process | GO:0043254 | 443 | 13 | 17256 | 270 |
PMAIP1,DACT1,PRKCD,BIK,GTF2F2,ARL2,ARHGAP28,TMOD2,DAB2IP,STXBP1,TLR6,PFN2,FHOD3 |
| 2.267e-02 | -3.79 | in utero embryonic development | biological process | GO:0001701 | 306 | 10 | 17256 | 270 |
EPB41L5,B9D1,MSX1,ACVR1,ST14,CEBPA,OVOL2,PRDM1,TANC2,APBA2 |
| 2.267e-02 | -3.79 | Cul3-RING ubiquitin ligase complex | cellular component | GO:0031463 | 70 | 4 | 18223 | 280 |
KLHL31,KLHL23,KLHL3,GAN |
| 2.275e-02 | -3.78 | Oncogenic MAPK signaling | REACTOME pathways | R-HSA-6802957 | 75 | 4 | 10287 | 148 |
KDM7A,DAB2IP,RASAL2,KIAA1549 |
| 2.277e-02 | -3.78 | enzyme activator activity | molecular function | GO:0008047 | 522 | 15 | 17224 | 278 |
ARHGAP26,RGS16,RGS17,RASAL2,ARHGEF11,DOCK1,PRKCD,SRGAP1,ARHGAP28,DAB2IP,WNT11,GAS6,TBC1D16,TIAM2,TBC1D8 |
| 2.278e-02 | -3.78 | lower_third | COSMIC cancer mutations | lower_third | 8160 | 149 | 17385 | 281 |
ARHGAP26,LGR4,RECK,PTPN21,ITPR2,ABAT,PRKCA,ABHD4,CACNB4,HMCN1,NCS1,EPDR1,CPNE2,FKBP9,DLX6,MARVELD2,TLN2,TSHR,ZNF391,WISP3,KLHL3,EXOC6B,CAPN5,SLC25A28,ABCC2,TNS1,ACVR2B,SGK2,SPNS1,TCF7L1,PLK2,RASGRF2,ERN1,ARHGAP28,TANC2,APBA2,LONRF1,GPR63,TMEM63C,SCN5A,RUNX2,SCART1,ZHX3,BVES,UBASH3B,CYP4V2,SETBP1,RASL11B,ATP6V1E2,CHADL,SLC36A4,DYNC1I1,FHOD3,MTUS1,NUMBL,RALGPS2,ZIC5,SRGAP1,GAN,EPB41L5,BDNF,SPATA13,PPFIA4,WDR25,WWC1,STRADB,PRDM1,LHPP,OR11H4,B4GALNT3,KIAA0355,ADAMTS3,ISM1,QPCTL,EMILIN2,HK2,CLMN,SMYD3,ZNF516,RASAL2,ST14,DOCK1,FAM131C,PLXNA2,RHPN2,KIF21B,COLEC10,RADIL,CBLN1,ZNF827,TMEM53,KCTD15,DACT1,EEPD1,ZNF521,MAP7,DAB2IP,MYH15,PDE4D,PJA1,DNAH5,HSPA2,DZANK1,PHLDB2,PDK1,SFXN4,ADCY1,NLGN4X,SATB2,TBC1D16,JAM3,WWTR1,PLEKHG1,P4HA1,DISP1,DBP,KLHL31,COBL,C2orf88,CCDC148,MXI1,PRSS16,ARHGEF11,KIF5C,OVOL2,ZNF219,GPR155,PRKCD,RASD2,EHD3,GTF2F2,PRICKLE2,TRIM3,KIAA0408,SMPDL3A,PARP9,MN1,TMC7,SLC40A1,MSX1,MPP1,NUAK2,PALLD,GPR137C,GPLD1,RERE,MAP2K6,MYOM2,PHC1 |
| 2.287e-02 | -3.78 | regulation of autophagy of mitochondrion | biological process | GO:1903146 | 39 | 3 | 17256 | 270 |
BNIP3,BNIP3L,HK2 |
| 2.287e-02 | -3.78 | forelimb morphogenesis | biological process | GO:0035136 | 39 | 3 | 17256 | 270 |
MSX1,RUNX2,RECK |
| 2.291e-02 | -3.78 | stem cell differentiation | biological process | GO:0048863 | 140 | 6 | 17256 | 270 |
EPCAM,MSX1,ACVR1,OVOL2,RUNX2,SOX21 |
| 2.291e-02 | -3.78 | MAPK7 (mitogen-activated protein kinase 7) | protein interactions | 5598 | 65 | 4 | 17029 | 283 |
SGK1,GAPDH,PRKCA,MYC |
| 2.302e-02 | -3.77 | GSE32986_UNSTIM_VS_GMCSF_AND_CURDLAN_LOWDOSE_STIM_DC_DN | MSigDB lists | GSE32986_UNSTIM_VS_GMCSF_AND_CURDLAN_LOWDOSE_STIM_DC_DN | 173 | 7 | 17377 | 282 |
DYRK1B,TTC22,ABAT,RUNX2,PNRC1,UBASH3B,CYP4V2 |
| 2.302e-02 | -3.77 | GAUSSMANN_MLL_AF4_FUSION_TARGETS_F_UP | MSigDB lists | GAUSSMANN_MLL_AF4_FUSION_TARGETS_F_UP | 173 | 7 | 17377 | 282 |
ARHGAP28,CLMN,IL17RD,GAS6,PNRC1,EMILIN2,FHOD3 |
| 2.302e-02 | -3.77 | MTOR_UP.V1_DN | MSigDB lists | MTOR_UP.V1_DN | 173 | 7 | 17377 | 282 |
SLC25A28,MOXD1,FANK1,MYC,BACE1,DDIT3,PHC1 |
| 2.302e-02 | -3.77 | GSE10325_LUPUS_CD4_TCELL_VS_LUPUS_BCELL_DN | MSigDB lists | GSE10325_LUPUS_CD4_TCELL_VS_LUPUS_BCELL_DN | 173 | 7 | 17377 | 282 |
SETBP1,CLMN,FGR,TNFRSF17,KMO,EHD3,PRKCD |
| 2.305e-02 | -3.77 | EF-hand_1 | pfam domains | PF00036 | 15 | 2 | 17054 | 271 |
HPCAL4,NCS1 |
| 2.305e-02 | -3.77 | RasGAP | pfam domains | PF00616 | 15 | 2 | 17054 | 271 |
DAB2IP,RASAL2 |
| 2.308e-02 | -3.77 | GO_CELL_JUNCTION | MSigDB lists | GO_CELL_JUNCTION | 1109 | 27 | 17377 | 282 |
ARHGAP26,EPB41L5,SCN5A,PHLDB2,PXN,SCAMP1,BVES,PTPN6,CAPN5,NLGN4X,NRN1,TNS1,ABCC2,PALLD,JAM3,CBLN1,HMCN1,NCS1,EPCAM,RGS17,LMLN,DACT1,MARVELD2,EHD3,PRKCD,ARHGAP28,TLN2 |
| 2.309e-02 | -3.77 | intracellular part | cellular component | GO:0044424 | 14262 | 233 | 18223 | 280 |
ARHGAP26,CCDC126,ACSL1,DUSP8,HEBP1,LSM11,PTPN21,ALG1L,NDRG2,CEBPA,ITPR2,ABAT,PRKCA,CACNB4,ABHD6,ABHD4,HMCN1,NCS1,EPDR1,CPNE2,FKBP9,PPM1E,PMAIP1,DLX6,MARVELD2,TMEM143,EPHB6,TLN2,FANK1,ZNF391,PGBD5,SMIM20,PNRC1,KLHL23,KLHL3,WISP3,EXOC6B,DSTN,ATOX1,CAPN5,BNIP3L,SLC25A28,TNS1,ACVR2B,PLEKHA1,SGK2,SAV1,GRK3,PLEKHB1,SPNS1,DYRK1B,TCF7L1,PLK2,RASGRF2,ERN1,ALDOA,ARHGAP28,MAPK13,TMOD2,DLX2,APBA2,LONRF1,GPR63,SCN5A,RGS16,RUNX2,ZNF395,SCART1,ZHX3,CYP2J2,FBXO4,UBASH3B,CYP4V2,ATP6V1E2,SETBP1,SLC36A4,HERC6,SATB1,DYNC1I1,PFN2,NIPSNAP3B,MYORG,FHOD3,MTUS1,NUMBL,SLC30A4,RALGPS2,MYC,ZIC5,SRGAP1,EBF4,GAN,INAVA,BNIP3,MOXD1,NCEH1,VGLL4,STXBP1,BARX1,GPR161,EPB41L5,ENAM,BDNF,QSOX1,IL17RD,B3GLCT,SPATA13,PPFIA4,WWC1,MAFB,STRADB,SHISA2,PRDM1,LHPP,ARRDC4,B4GALNT3,ZNF558,QPCTL,HK2,CLMN,IQSEC2,RNF122,SMYD3,ZNF516,SCAMP1,RASAL2,DOCK1,C4A,CCDC110,RHPN2,FAM198B,KIF21B,COLEC10,RADIL,TIAM2,TMEM53,ZNF827,KMO,DACT1,RPS6KL1,ZDHHC23,ZNF521,MAP7,DAB2IP,MYH15,PDE4D,PJA1,RAB27B,DNAH5,TMEM120B,HSPA2,PHLDB2,GAPDH,UROS,PDK1,SOX21,PTPN6,CYB5R2,SFXN4,ADCY1,WNT11,SATB2,PXYLP1,RAB38,TBC1D16,TRIQK,JAM3,CENPV,IFT81,LMLN,ZNF697,RBPMS2,WFS1,WWTR1,PLEKHG1,P4HA1,DBP,KLHL31,COBL,KCTD1,NECAB2,MXI1,PRSS16,ARHGEF11,BACE1,BLVRB,BIK,CCNJL,ARL2,KIF5C,SLX1B,GAS6,OVOL2,ZNF219,NEO1,KDM7A,RGS17,GPR155,PRKCD,EHD3,GTF2F2,ACTA2,SGK1,PRICKLE2,TRIM3,PARP9,B9D1,SLC40A1,LZTS3,PXN,MSX1,MPP1,CCDC184,NUAK2,OGDHL,EXOG,PALLD,TLR6,RERE,GPLD1,CTIF,TRIB3,FGR,FMO4,GNAO1,MAP2K6,KIAA0513,MYOM2,RNF157,B4GALT7,DDIT3,PKIA,PHC1 |
| 2.313e-02 | -3.77 | cerebrum | COSMIC cancer mutations | cerebrum | 67 | 4 | 17385 | 281 |
MYH15,KIAA1549,UBASH3B,GAN |
| 2.319e-02 | -3.76 | macromolecule modification | biological process | GO:0043412 | 3348 | 66 | 17256 | 270 |
CCDC126,LONRF1,ACVR1,DUSP8,RASAL2,RECK,C4A,FBXO4,UBASH3B,PTPN21,ALG1L,NRN1,GAS6,HERC6,PRKCA,SATB1,KDM7A,FKBP9,PPM1E,RPS6KL1,MYC,PRKCD,ZDHHC23,GAN,SGK1,TRIM3,DAB2IP,PJA1,EPHB6,PARP9,ENAM,QSOX1,IL17RD,GAPDH,B3GLCT,PDK1,KLHL23,KLHL3,PTPN6,NUAK2,STRADB,WNT11,ACVR2B,LHPP,RAB38,SGK2,ARRDC4,GRK3,GPLD1,DYRK1B,TRIB3,FGR,RASGRF2,PLK2,WFS1,MAP2K6,QPCTL,ERN1,WWTR1,P4HA1,MAPK13,KLHL31,RNF122,SMYD3,B4GALT7,PHC1 |
| 2.324e-02 | -3.76 | central_nervous_system-thalamus-glioma-astrocytoma_Grade_III | COSMIC cancer mutations | central_nervous_system-thalamus-glioma-astrocytoma_Grade_III | 38 | 3 | 17385 | 281 |
KIAA1549,CTIF,PLXNA2 |
| 2.324e-02 | -3.76 | GO_DIVALENT_INORGANIC_CATION_TRANSPORT | MSigDB lists | GO_DIVALENT_INORGANIC_CATION_TRANSPORT | 254 | 9 | 17377 | 282 |
SLC40A1,SLC30A4,SLC39A8,TMEM37,GAS6,ITPR2,CACNB4,DDIT3,NCS1 |
| 2.324e-02 | -3.76 | V$BACH2_01 | MSigDB lists | V$BACH2_01 | 254 | 9 | 17377 | 282 |
ZNF827,GAPDH,ALDOA,NDRG2,STRADB,SGK1,PRDM1,DDIT3,NCS1 |
| 2.324e-02 | -3.76 | V$ER_Q6 | MSigDB lists | V$ER_Q6 | 254 | 9 | 17377 | 282 |
TMEM53,ZNF827,MXI1,ALDOA,ERN1,NDRG2,OVOL2,RAB27B,SATB1 |
| 2.331e-02 | -3.76 | cofactor biosynthetic process | biological process | GO:0051188 | 221 | 8 | 17256 | 270 |
ACSL1,GAPDH,UROS,KMO,ALDOA,OGDHL,HK2,PARP9 |
| 2.337e-02 | -3.76 | RasGAP_dom | interpro domains | IPR001936 | 15 | 2 | 18492 | 296 |
DAB2IP,RASAL2 |
| 2.339e-02 | -3.76 | TSP1 | prosite domains | PS50092 | 65 | 4 | 12060 | 202 |
WISP3,ADAMTS3,HMCN1,ISM1 |
| 2.348e-02 | -3.75 | MORF_ERCC2 | MSigDB lists | MORF_ERCC2 | 100 | 5 | 17377 | 282 |
P4HA1,TLN2,SCAMP1,PLEKHB1,RERE |
| 2.348e-02 | -3.75 | WOO_LIVER_CANCER_RECURRENCE_UP | MSigDB lists | WOO_LIVER_CANCER_RECURRENCE_UP | 100 | 5 | 17377 | 282 |
QSOX1,PFN2,ALDOA,DDIT3,HK2 |
| 2.348e-02 | -3.75 | GGCAGAC,MIR-346 | MSigDB lists | GGCAGAC,MIR-346 | 38 | 3 | 17377 | 282 |
PRICKLE2,KCTD15,PFN2 |
| 2.348e-02 | -3.75 | GO_APICAL_JUNCTION_ASSEMBLY | MSigDB lists | GO_APICAL_JUNCTION_ASSEMBLY | 38 | 3 | 17377 | 282 |
ARL2,WNT11,MARVELD2 |
| 2.348e-02 | -3.75 | GO_SPLEEN_DEVELOPMENT | MSigDB lists | GO_SPLEEN_DEVELOPMENT | 38 | 3 | 17377 | 282 |
SLC40A1,CACNB4,BARX1 |
| 2.348e-02 | -3.75 | GO_VOLTAGE_GATED_CALCIUM_CHANNEL_COMPLEX | MSigDB lists | GO_VOLTAGE_GATED_CALCIUM_CHANNEL_COMPLEX | 38 | 3 | 17377 | 282 |
PDE4D,CACNB4,HSPA2 |
| 2.348e-02 | -3.75 | GO_PLATELET_AGGREGATION | MSigDB lists | GO_PLATELET_AGGREGATION | 38 | 3 | 17377 | 282 |
GAS6,STXBP1,PTPN6 |
| 2.348e-02 | -3.75 | CTCTATG,MIR-368 | MSigDB lists | CTCTATG,MIR-368 | 38 | 3 | 17377 | 282 |
BDNF,SATB2,RASAL2 |
| 2.348e-02 | -3.75 | GO_MESENCHYME_MORPHOGENESIS | MSigDB lists | GO_MESENCHYME_MORPHOGENESIS | 38 | 3 | 17377 | 282 |
ACTA2,WNT11,MSX1 |
| 2.362e-02 | -3.75 | positive regulation of cellular protein catabolic process | biological process | GO:1903364 | 141 | 6 | 17256 | 270 |
LONRF1,TRIB3,DAB2IP,CEBPA,DACT1,PLK2 |
| 2.365e-02 | -3.74 | GACAATC,MIR-219 | MSigDB lists | GACAATC,MIR-219 | 136 | 6 | 17377 | 282 |
ZNF827,SCN5A,PDE4D,SLC30A4,RECK,UBASH3B |
| 2.366e-02 | -3.74 | GSE2706_UNSTIM_VS_8H_R848_DC_UP | MSigDB lists | GSE2706_UNSTIM_VS_8H_R848_DC_UP | 174 | 7 | 17377 | 282 |
KIAA0513,CLMN,ABAT,DBP,UROS,WFS1,BLVRB |
| 2.366e-02 | -3.74 | GSE25088_WT_VS_STAT6_KO_MACROPHAGE_ROSIGLITAZONE_AND_IL4_STIM_DN | MSigDB lists | GSE25088_WT_VS_STAT6_KO_MACROPHAGE_ROSIGLITAZONE_AND_IL4_STIM_DN | 174 | 7 | 17377 | 282 |
ACTA2,KIF5C,KCTD15,RUNX2,RNF157,BIK,NEO1 |
| 2.366e-02 | -3.74 | GSE37416_CTRL_VS_3H_F_TULARENSIS_LVS_NEUTROPHIL_DN | MSigDB lists | GSE37416_CTRL_VS_3H_F_TULARENSIS_LVS_NEUTROPHIL_DN | 174 | 7 | 17377 | 282 |
P4HA1,BNIP3,ENAM,PDK1,VGLL4,ALDOA,HK2 |
| 2.381e-02 | -3.74 | central_nervous_system-cerebellum-primitive_neuroectodermal_tumour-medulloblastoma-SHH_subtype | COSMIC cancer mutations | central_nervous_system-cerebellum-primitive_neuroectodermal_tumour-medulloblastoma-SHH_subtype | 667 | 18 | 17385 | 281 |
BDNF,RUNX2,LGR4,SETBP1,SLC36A4,SLC2A13,ITPR2,PALLD,HMCN1,FHOD3,MTUS1,ANKRD31,KMO,GNAO1,SRGAP1,DAB2IP,PDE4D,COBL |
| 2.381e-02 | -3.74 | CACGTG_V$MYC_Q2 | MSigDB lists | CACGTG_V$MYC_Q2 | 960 | 24 | 17377 | 282 |
CCDC126,BDNF,GAPDH,RUNX2,OGDHL,ARL2,SATB2,CEBPA,ACVR2B,ARRDC4,HPCAL4,MTUS1,CTIF,DYRK1B,SPNS1,KCTD15,LMLN,ADAMTS3,RASD2,ALDOA,TRIM3,MAP7,SGK1,DLX2 |
| 2.382e-02 | -3.74 | NGF signalling via TRKA from the plasma membrane | REACTOME pathways | R-HSA-187037 | 387 | 11 | 10287 | 148 |
IL17RD,TRIB3,RASAL2,DUSP8,RASGRF2,PRKCD,ADCY1,DAB2IP,MAPK13,ITPR2,PRKCA |
| 2.384e-02 | -3.74 | LINDGREN_BLADDER_CANCER_CLUSTER_3_DN | MSigDB lists | LINDGREN_BLADDER_CANCER_CLUSTER_3_DN | 214 | 8 | 17377 | 282 |
ZNF827,ZNF516,PXN,CFHR1,MYC,DAB2IP,PDE4D,EPHB6 |
| 2.391e-02 | -3.73 | kidney-carcinoma | COSMIC cancer mutations | kidney-carcinoma | 3756 | 75 | 17385 | 281 |
ARHGAP26,ACVR1,DUSP8,DOCK1,PTPN21,ITPR2,COLEC10,PRKCA,FKBP9,PPM1E,PMAIP1,DACT1,RPS6KL1,ZNF521,PDE4D,RAB27B,HSPA2,GAPDH,PNRC1,PDK1,PTPN6,BNIP3L,PLEKHA1,RAB38,ACVR2B,SGK2,SAV1,PLEKHB1,DYRK1B,PLK2,RASGRF2,ERN1,ALDOA,TNFSF15,MAPK13,RGS16,RUNX2,MXI1,ARHGEF11,FBXO4,BIK,ARL2,TNFRSF10C,GAS6,SATB1,RGS17,NUMBL,RALGPS2,MYC,PRKCD,RASD2,SRGAP1,TRIM3,SGK1,BNIP3,PXN,SPATA13,NUAK2,PPFIA4,MAFB,STRADB,PRDM1,GPLD1,TRIB3,FGR,ADAMTS3,FMO4,GNAO1,MAP2K6,HK2,TNFRSF17,RNF157,RNF122,SMYD3,DDIT3 |
| 2.392e-02 | -3.73 | CHEMNITZ_RESPONSE_TO_PROSTAGLANDIN_E2_DN | MSigDB lists | CHEMNITZ_RESPONSE_TO_PROSTAGLANDIN_E2_DN | 341 | 11 | 17377 | 282 |
EPB41L5,CCDC148,ST14,SLC39A8,CYP4V2,MAP7,CCDC122,SATB2,SLC2A13,TNFRSF10C,COBL |
| 2.392e-02 | -3.73 | GO_NEGATIVE_REGULATION_OF_TRANSFERASE_ACTIVITY | MSigDB lists | GO_NEGATIVE_REGULATION_OF_TRANSFERASE_ACTIVITY | 341 | 11 | 17377 | 282 |
TRIB3,PPM1E,DUSP8,UBASH3B,PTPN6,PRKCD,WWTR1,DAB2IP,CEBPA,SMYD3,PKIA |
| 2.397e-02 | -3.73 | LEIN_LOCALIZED_TO_DISTAL_AND_PROXIMAL_DENDRITES | MSigDB lists | LEIN_LOCALIZED_TO_DISTAL_AND_PROXIMAL_DENDRITES | 15 | 2 | 17377 | 282 |
HPCAL4,ADCY1 |
| 2.397e-02 | -3.73 | DAVICIONI_RHABDOMYOSARCOMA_PAX_FOXO1_FUSION_DN | MSigDB lists | DAVICIONI_RHABDOMYOSARCOMA_PAX_FOXO1_FUSION_DN | 15 | 2 | 17377 | 282 |
MOXD1,PLK2 |
| 2.397e-02 | -3.73 | MODULE_227 | MSigDB lists | MODULE_227 | 15 | 2 | 17377 | 282 |
UROS,BLVRB |
| 2.397e-02 | -3.73 | GO_PHOSPHOTYROSINE_BINDING | MSigDB lists | GO_PHOSPHOTYROSINE_BINDING | 15 | 2 | 17377 | 282 |
FGR,PTPN6 |
| 2.401e-02 | -3.73 | epithelial cell development | biological process | GO:0002064 | 181 | 7 | 17256 | 270 |
ACTA2,EPB41L5,PRDM1,PDE4D,PALLD,ST14,MARVELD2 |
| 2.408e-02 | -3.73 | GNA13 (G protein subunit alpha 13) | protein interactions | 10672 | 66 | 4 | 17029 | 283 |
RGS16,TSHR,ARHGEF11,PRKCD |
| 2.412e-02 | -3.72 | SHH_subtype | COSMIC cancer mutations | SHH_subtype | 668 | 18 | 17385 | 281 |
BDNF,RUNX2,LGR4,SETBP1,SLC36A4,SLC2A13,ITPR2,PALLD,HMCN1,FHOD3,MTUS1,ANKRD31,KMO,GNAO1,SRGAP1,DAB2IP,PDE4D,COBL |
| 2.416e-02 | -3.72 | monosaccharide binding | molecular function | GO:0048029 | 68 | 4 | 17224 | 278 |
P4HA1,COLEC10,ALDOA,HK2 |
| 2.421e-02 | -3.72 | - | gene3d domains | 2.20.100.10 | 62 | 4 | 8148 | 145 |
WISP3,ADAMTS3,HMCN1,ISM1 |
| 2.427e-02 | -3.72 | Metabolism of porphyrins | REACTOME pathways | R-HSA-189445 | 17 | 2 | 10287 | 148 |
UROS,BLVRB |
| 2.427e-02 | -3.72 | Platelet sensitization by LDL | REACTOME pathways | R-HSA-432142 | 17 | 2 | 10287 | 148 |
FGR,PTPN6 |
| 2.427e-02 | -3.72 | Acetylcholine Neurotransmitter Release Cycle | REACTOME pathways | R-HSA-264642 | 17 | 2 | 10287 | 148 |
PPFIA4,STXBP1 |
| 2.429e-02 | -3.72 | Asthma(PMID:19426955) | GWAS genes | Asthma(PMID:19426955) | 1 | 1 | 2388 | 58 |
PDE4D |
| 2.429e-02 | -3.72 | PR interval(PMID:21347284) | GWAS genes | PR interval(PMID:21347284) | 1 | 1 | 2388 | 58 |
SCN5A |
| 2.429e-02 | -3.72 | Amyotrophic lateral sclerosis(PMID:17827064) | GWAS genes | Amyotrophic lateral sclerosis(PMID:17827064) | 1 | 1 | 2388 | 58 |
ITPR2 |
| 2.429e-02 | -3.72 | Parkinson's disease(PMID:19915576) | GWAS genes | Parkinson's disease(PMID:19915576) | 1 | 1 | 2388 | 58 |
SLC2A13 |
| 2.429e-02 | -3.72 | Neuroticism(PMID:17667963) | GWAS genes | Neuroticism(PMID:17667963) | 1 | 1 | 2388 | 58 |
PDE4D |
| 2.432e-02 | -3.72 | GSE37301_COMMON_LYMPHOID_PROGENITOR_VS_GRAN_MONO_PROGENITOR_DN | MSigDB lists | GSE37301_COMMON_LYMPHOID_PROGENITOR_VS_GRAN_MONO_PROGENITOR_DN | 175 | 7 | 17377 | 282 |
SGK1,TANC2,LGR4,CACNB4,PLK2,SMYD3,MYC |
| 2.432e-02 | -3.72 | IL2_UP.V1_DN | MSigDB lists | IL2_UP.V1_DN | 175 | 7 | 17377 | 282 |
THAP10,PNRC1,PRSS16,TANC2,MAP2K6,CBLN1,ZNF391 |
| 2.435e-02 | -3.72 | negative regulation of protein serine/threonine kinase activity | biological process | GO:0071901 | 142 | 6 | 17256 | 270 |
DAB2IP,CEBPA,DUSP8,PTPN6,PRKCD,PKIA |
| 2.439e-02 | -3.71 | GO_REGULATION_OF_FAT_CELL_DIFFERENTIATION | MSigDB lists | GO_REGULATION_OF_FAT_CELL_DIFFERENTIATION | 101 | 5 | 17377 | 282 |
TRIB3,CEBPA,SAV1,WWTR1,DDIT3 |
| 2.439e-02 | -3.71 | KEGG_MELANOGENESIS | MSigDB lists | KEGG_MELANOGENESIS | 101 | 5 | 17377 | 282 |
TCF7L1,WNT11,PRKCA,GNAO1,ADCY1 |
| 2.440e-02 | -3.71 | BROWNE_HCMV_INFECTION_24HR_UP | MSigDB lists | BROWNE_HCMV_INFECTION_24HR_UP | 137 | 6 | 17377 | 282 |
EPCAM,WNT11,ABAT,TNFRSF17,NEO1,PLXNA2 |
| 2.440e-02 | -3.71 | GSE12963_ENV_NEF_VS_ENV_NEF_AND_VPR_DEFICIENT_HIV1_INF_CD4_TCELL_DN | MSigDB lists | GSE12963_ENV_NEF_VS_ENV_NEF_AND_VPR_DEFICIENT_HIV1_INF_CD4_TCELL_DN | 137 | 6 | 17377 | 282 |
CPNE2,MSX1,GAPDH,RAB27B,TSHR,NEO1 |
| 2.443e-02 | -3.71 | V$FOXJ2_02 | MSigDB lists | V$FOXJ2_02 | 215 | 8 | 17377 | 282 |
MXI1,KIAA0355,SATB2,PDE4D,DLX2,PRDM1,SATB1,NEO1 |
| 2.445e-02 | -3.71 | positive regulation of biomineral tissue development | biological process | GO:0070169 | 40 | 3 | 17256 | 270 |
ENAM,ACVR2B,ACVR1 |
| 2.445e-02 | -3.71 | ventricular septum morphogenesis | biological process | GO:0060412 | 40 | 3 | 17256 | 270 |
WNT11,ACVR1,SAV1 |
| 2.451e-02 | -3.71 | plasma membrane region | cellular component | GO:0098590 | 1070 | 25 | 18223 | 280 |
EPB41L5,SCN5A,SLC40A1,LZTS3,ST14,BVES,SPATA13,NLGN4X,WWC1,ABCC2,PLEKHA1,CBLN1,HMCN1,NCS1,EPCAM,FGR,MARVELD2,EHD3,MAP7,PDE4D,DISP1,RAB27B,STXBP1,TSHR,GPR161 |
| 2.455e-02 | -3.71 | WDYHV1 (WDYHV motif containing 1) | protein interactions | 55093 | 134 | 6 | 17029 | 283 |
LONRF1,NECAB2,ZHX3,KCTD1,ERN1,CCDC184 |
| 2.458e-02 | -3.71 | ACACTCC,MIR-122A | MSigDB lists | ACACTCC,MIR-122A | 68 | 4 | 17377 | 282 |
P4HA1,ZNF827,SLC39A8,ALDOA |
| 2.458e-02 | -3.71 | GO_REGULATION_OF_ADENYLATE_CYCLASE_ACTIVITY | MSigDB lists | GO_REGULATION_OF_ADENYLATE_CYCLASE_ACTIVITY | 68 | 4 | 17377 | 282 |
PRKCA,TSHR,WFS1,ADCY1 |
| 2.463e-02 | -3.70 | response to hydrogen peroxide | biological process | GO:0042542 | 105 | 5 | 17256 | 270 |
MAPK13,BNIP3,PLEKHA1,GNAO1,PRKCD |
| 2.476e-02 | -3.70 | Ferroptosis | KEGG pathways | hsa04216 | 40 | 3 | 7161 | 113 |
SLC40A1,ACSL1,SLC39A8 |
| 2.476e-02 | -3.70 | Ferroptosis | KEGG pathways | ko04216 | 40 | 3 | 7161 | 113 |
SLC40A1,ACSL1,SLC39A8 |
| 2.480e-02 | -3.70 | monooxygenase activity | molecular function | GO:0004497 | 102 | 5 | 17224 | 278 |
MOXD1,KMO,FMO4,CYP2J2,CYP4V2 |
| 2.483e-02 | -3.70 | V$CEBP_Q2_01 | MSigDB lists | V$CEBP_Q2_01 | 257 | 9 | 17377 | 282 |
BDNF,SLC40A1,TCF7L1,MAP2K6,TNFSF15,PDE4D,EPHB6,ABHD6,NEO1 |
| 2.497e-02 | -3.69 | LTF (lactotransferrin) | protein interactions | 4057 | 38 | 3 | 17029 | 283 |
SGK1,CEBPA,CCDC148 |
| 2.497e-02 | -3.69 | SSH1 (slingshot protein phosphatase 1) | protein interactions | 54434 | 38 | 3 | 17029 | 283 |
ACTA2,TMOD2,DSTN |
| 2.497e-02 | -3.69 | cytoplasm | cellular component | GO:0005737 | 11448 | 192 | 18223 | 280 |
ARHGAP26,CCDC126,ACSL1,DUSP8,HEBP1,PTPN21,ALG1L,NDRG2,ITPR2,ABAT,PRKCA,CACNB4,ABHD6,ABHD4,HMCN1,NCS1,EPDR1,CPNE2,FKBP9,PPM1E,PMAIP1,MARVELD2,TMEM143,EPHB6,TLN2,FANK1,SMIM20,PNRC1,KLHL3,WISP3,EXOC6B,DSTN,ATOX1,CAPN5,BNIP3L,SLC25A28,TNS1,ACVR2B,PLEKHA1,SGK2,SAV1,GRK3,PLEKHB1,SPNS1,TCF7L1,PLK2,RASGRF2,ERN1,ALDOA,ARHGAP28,MAPK13,TMOD2,APBA2,LONRF1,GPR63,SCN5A,RGS16,RUNX2,ZNF395,SCART1,CYP2J2,FBXO4,UBASH3B,CYP4V2,ATP6V1E2,SETBP1,SLC36A4,HERC6,DYNC1I1,PFN2,NIPSNAP3B,MYORG,FHOD3,MTUS1,NUMBL,SLC30A4,RALGPS2,MYC,SRGAP1,GAN,INAVA,BNIP3,MOXD1,NCEH1,STXBP1,GPR161,EPB41L5,ENAM,BDNF,QSOX1,IL17RD,B3GLCT,SPATA13,PPFIA4,WWC1,STRADB,SHISA2,PRDM1,LHPP,ARRDC4,B4GALNT3,QPCTL,HK2,CLMN,IQSEC2,RNF122,SMYD3,RASAL2,SCAMP1,DOCK1,C4A,RHPN2,FAM198B,COLEC10,KIF21B,TIAM2,KMO,DACT1,RPS6KL1,ZDHHC23,MAP7,DAB2IP,MYH15,PDE4D,PJA1,RAB27B,DNAH5,HSPA2,PHLDB2,GAPDH,UROS,PDK1,SFXN4,CYB5R2,PTPN6,ADCY1,WNT11,PXYLP1,RAB38,TBC1D16,TRIQK,JAM3,CENPV,LMLN,RBPMS2,WFS1,WWTR1,P4HA1,COBL,NECAB2,MXI1,PRSS16,ARHGEF11,BACE1,BLVRB,BIK,ARL2,KIF5C,GAS6,NEO1,RGS17,GPR155,PRKCD,EHD3,ACTA2,SGK1,TRIM3,PRICKLE2,PARP9,B9D1,SLC40A1,LZTS3,PXN,MPP1,CCDC184,NUAK2,OGDHL,PALLD,EXOG,TLR6,GPLD1,CTIF,TRIB3,FGR,FMO4,MAP2K6,KIAA0513,MYOM2,RNF157,B4GALT7,DDIT3,PKIA |
| 2.499e-02 | -3.69 | GSE12366_GC_VS_MEMORY_BCELL_UP | MSigDB lists | GSE12366_GC_VS_MEMORY_BCELL_UP | 176 | 7 | 17377 | 282 |
ARHGAP28,SGK1,ZNF827,ST14,VGLL4,HSPA2,SLC39A8 |
| 2.499e-02 | -3.69 | GSE32986_UNSTIM_VS_CURDLAN_HIGHDOSE_STIM_DC_DN | MSigDB lists | GSE32986_UNSTIM_VS_CURDLAN_HIGHDOSE_STIM_DC_DN | 176 | 7 | 17377 | 282 |
DYRK1B,TTC22,ABAT,RUNX2,PNRC1,UROS,CYP4V2 |
| 2.499e-02 | -3.69 | GSE14000_UNSTIM_VS_4H_LPS_DC_TRANSLATED_RNA_DN | MSigDB lists | GSE14000_UNSTIM_VS_4H_LPS_DC_TRANSLATED_RNA_DN | 176 | 7 | 17377 | 282 |
TNFSF15,SLC25A28,ACSL1,HERC6,PMAIP1,RECK,PARP9 |
| 2.499e-02 | -3.69 | GSE3982_MAST_CELL_VS_BCELL_DN | MSigDB lists | GSE3982_MAST_CELL_VS_BCELL_DN | 176 | 7 | 17377 | 282 |
SETBP1,SLC25A28,PDK1,PNRC1,PRSS16,ZNF395,JAM3 |
| 2.499e-02 | -3.69 | GSE18791_CTRL_VS_NEWCASTLE_VIRUS_DC_8H_DN | MSigDB lists | GSE18791_CTRL_VS_NEWCASTLE_VIRUS_DC_8H_DN | 176 | 7 | 17377 | 282 |
HERC6,PMAIP1,ARHGEF11,HPCAL4,DDIT3,PARP9,HK2 |
| 2.499e-02 | -3.69 | GSE2706_UNSTIM_VS_2H_R848_DC_DN | MSigDB lists | GSE2706_UNSTIM_VS_2H_R848_DC_DN | 176 | 7 | 17377 | 282 |
TNFSF15,SHISA2,ACSL1,HERC6,ZNF697,PMAIP1,RPS6KL1 |
| 2.506e-02 | -3.69 | DLX2 (distal-less homeobox 2) | protein interactions | 1746 | 15 | 2 | 17029 | 283 |
MSX1,DLX2 |
| 2.506e-02 | -3.69 | WNK4 (WNK lysine deficient protein kinase 4) | protein interactions | 65266 | 15 | 2 | 17029 | 283 |
SGK1,KLHL3 |
| 2.506e-02 | -3.69 | RGS16 (regulator of G protein signaling 16) | protein interactions | 6004 | 15 | 2 | 17029 | 283 |
ST14,GNAO1 |
| 2.506e-02 | -3.69 | PILRA (paired immunoglobin like type 2 receptor alpha) | protein interactions | 29992 | 15 | 2 | 17029 | 283 |
B4GALNT3,PTPN6 |
| 2.506e-02 | -3.69 | TRMT44 (tRNA methyltransferase 44 homolog) | protein interactions | 152992 | 15 | 2 | 17029 | 283 |
CCNJL,TSHR |
| 2.510e-02 | -3.68 | mesenchymal cell differentiation | biological process | GO:0048762 | 143 | 6 | 17256 | 270 |
EPB41L5,WNT11,MSX1,ACVR1,OVOL2,WWTR1 |
| 2.512e-02 | -3.68 | human chr13q14.12-q14.13 | chromosome location | human chr13q14.12-q14.13 | 2 | 1 | 26185 | 331 |
GTF2F2 |
| 2.512e-02 | -3.68 | human chr19q11 | chromosome location | human chr19q11 | 2 | 1 | 26185 | 331 |
LINC00662 |
| 2.514e-02 | -3.68 | KORKOLA_EMBRYONAL_CARCINOMA_UP | MSigDB lists | KORKOLA_EMBRYONAL_CARCINOMA_UP | 39 | 3 | 17377 | 282 |
GAPDH,PTPN6,PHC1 |
| 2.514e-02 | -3.68 | BIOCARTA_P38MAPK_PATHWAY | MSigDB lists | BIOCARTA_P38MAPK_PATHWAY | 39 | 3 | 17377 | 282 |
MAP2K6,MYC,DDIT3 |
| 2.514e-02 | -3.68 | chr2q32 | MSigDB lists | chr2q32 | 39 | 3 | 17377 | 282 |
C2orf88,SLC40A1,DLX2 |
| 2.514e-02 | -3.68 | KORKOLA_SEMINOMA_UP | MSigDB lists | KORKOLA_SEMINOMA_UP | 39 | 3 | 17377 | 282 |
GAPDH,PTPN6,PHC1 |
| 2.514e-02 | -3.68 | GO_FORELIMB_MORPHOGENESIS | MSigDB lists | GO_FORELIMB_MORPHOGENESIS | 39 | 3 | 17377 | 282 |
MSX1,RUNX2,RECK |
| 2.514e-02 | -3.68 | GO_ACTIVATION_OF_ADENYLATE_CYCLASE_ACTIVITY | MSigDB lists | GO_ACTIVATION_OF_ADENYLATE_CYCLASE_ACTIVITY | 39 | 3 | 17377 | 282 |
PRKCA,TSHR,ADCY1 |
| 2.514e-02 | -3.68 | GO_ANATOMICAL_STRUCTURE_MATURATION | MSigDB lists | GO_ANATOMICAL_STRUCTURE_MATURATION | 39 | 3 | 17377 | 282 |
RECK,DDIT3,RERE |
| 2.518e-02 | -3.68 | OHGUCHI_LIVER_HNF4A_TARGETS_DN | MSigDB lists | OHGUCHI_LIVER_HNF4A_TARGETS_DN | 138 | 6 | 17377 | 282 |
TMC7,ABAT,KMO,CFHR1,HEBP1,CYP4V2 |
| 2.518e-02 | -3.68 | MORF_CDC2L5 | MSigDB lists | MORF_CDC2L5 | 138 | 6 | 17377 | 282 |
TTC22,MSX1,TLN2,SCAMP1,PLEKHB1,RERE |
| 2.523e-02 | -3.68 | GO_NEURON_PROJECTION_DEVELOPMENT | MSigDB lists | GO_NEURON_PROJECTION_DEVELOPMENT | 526 | 15 | 17377 | 282 |
BDNF,NUMBL,GNAO1,ADCY1,PLXNA2,EFNA3,KIF5C,SGK1,CLMN,DAB2IP,STXBP1,COBL,JAM3,NEO1,RERE |
| 2.528e-02 | -3.68 | PKN1 (protein kinase N1) | protein interactions | 5585 | 67 | 4 | 17029 | 283 |
ARHGAP26,PDK1,MAP2K6,MYC |
| 2.533e-02 | -3.68 | positive regulation of cytokine production involved in inflammatory response | biological process | GO:1900017 | 16 | 2 | 17256 | 270 |
IL17D,TLR6 |
| 2.533e-02 | -3.68 | cellular response to arsenic-containing substance | biological process | GO:0071243 | 16 | 2 | 17256 | 270 |
MAPK13,UROS |
| 2.533e-02 | -3.68 | regulation of glutamate secretion | biological process | GO:0014048 | 16 | 2 | 17256 | 270 |
KMO,STXBP1 |
| 2.533e-02 | -3.68 | regulation of cytolysis | biological process | GO:0042268 | 16 | 2 | 17256 | 270 |
CFHR1,GPLD1 |
| 2.533e-02 | -3.68 | intrinsic apoptotic signaling pathway in response to oxidative stress | biological process | GO:0008631 | 16 | 2 | 17256 | 270 |
PDK1,PRKCD |
| 2.535e-02 | -3.68 | TUBA1B (tubulin alpha 1b) | protein interactions | 10376 | 135 | 6 | 17029 | 283 |
SLX1B,PXN,LGR4,UBASH3B,MYC,GAN |
| 2.539e-02 | -3.67 | adrenal_gland | COSMIC cancer mutations | adrenal_gland | 2689 | 56 | 17385 | 281 |
CCDC148,ZHX3,DOCK1,ST14,ARHGEF11,CCDC110,PTPN21,CYP4V2,PLXNA2,SETBP1,KIF5C,ZNF219,HMCN1,TIAM2,MTUS1,TMEM53,MARVELD2,GPR155,ZIC5,EHD3,RASD2,EBF4,SRGAP1,PRICKLE2,DAB2IP,MYH15,NCEH1,RAB27B,TLN2,MOXD1,DNAH5,HSPA2,GPR161,PGBD5,C3orf67,ZNF391,IL17RD,QSOX1,KLHL3,PTPN6,PPFIA4,WNT11,LHPP,PRDM1,JAM3,ZNF558,NT5DC2,RERE,IFT81,TCF7L1,KIAA0355,HK2,KIAA0513,TNFSF15,MYOM2,TANC2 |
| 2.540e-02 | -3.67 | RAS_GTPASE_ACTIV_2 | prosite domains | PS50018 | 15 | 2 | 12060 | 202 |
DAB2IP,RASAL2 |
| 2.541e-02 | -3.67 | PROTEIN_KINASE_ATP | prosite domains | PS00107 | 378 | 12 | 12060 | 202 |
DYRK1B,FGR,ACVR1,MAP2K6,PLK2,PRKCD,NUAK2,SGK1,MAPK13,SGK2,PRKCA,GRK3 |
| 2.553e-02 | -3.67 | positive regulation of proteasomal protein catabolic process | biological process | GO:1901800 | 106 | 5 | 17256 | 270 |
LONRF1,TRIB3,DAB2IP,CEBPA,PLK2 |
| 2.557e-02 | -3.67 | contractile fiber | cellular component | GO:0043292 | 229 | 8 | 18223 | 280 |
ACTA2,MYH15,SCN5A,MYOM2,TMOD2,PALLD,FHOD3,ALDOA |
| 2.559e-02 | -3.67 | renal system development | biological process | GO:0072001 | 268 | 9 | 17256 | 270 |
EPCAM,LGR4,KLHL3,MYC,WFS1,WWTR1,ACTA2,WNT11,ACVR2B |
| 2.563e-02 | -3.66 | MARKEY_RB1_ACUTE_LOF_DN | MSigDB lists | MARKEY_RB1_ACUTE_LOF_DN | 217 | 8 | 17377 | 282 |
NDRG2,MXI1,PDK1,PTPN6,DDIT3,SMPDL3A,CYP4V2,BNIP3L |
| 2.563e-02 | -3.66 | CHYLA_CBFA2T3_TARGETS_DN | MSigDB lists | CHYLA_CBFA2T3_TARGETS_DN | 217 | 8 | 17377 | 282 |
DUSP8,SLC39A8,HEBP1,MARVELD2,BLVRB,TNS1,CENPV,EPDR1 |
| 2.563e-02 | -3.66 | BROWNE_HCMV_INFECTION_16HR_UP | MSigDB lists | BROWNE_HCMV_INFECTION_16HR_UP | 217 | 8 | 17377 | 282 |
PDE4D,SLC30A4,ADAMTS3,KLHL23,DYNC1I1,HSPA2,PRKCD,PTPN21 |
| 2.567e-02 | -3.66 | PTCH1 (patched 1) | protein interactions | 5727 | 100 | 5 | 17029 | 283 |
PXYLP1,B3GLCT,MOXD1,B4GALT7,MYORG |
| 2.567e-02 | -3.66 | GSE22443_NAIVE_VS_ACT_AND_IL12_TREATED_CD8_TCELL_DN | MSigDB lists | GSE22443_NAIVE_VS_ACT_AND_IL12_TREATED_CD8_TCELL_DN | 177 | 7 | 17377 | 282 |
SGK1,C2orf88,DISP1,PDE4D,B4GALT7,GTF2F2,EEPD1 |
| 2.567e-02 | -3.66 | LTE2_UP.V1_UP | MSigDB lists | LTE2_UP.V1_UP | 177 | 7 | 17377 | 282 |
CLMN,PNRC1,UROS,KMO,EHD3,TBC1D8,BNIP3L |
| 2.567e-02 | -3.66 | GSE8921_UNSTIM_0H_VS_TLR1_2_STIM_MONOCYTE_24H_UP | MSigDB lists | GSE8921_UNSTIM_0H_VS_TLR1_2_STIM_MONOCYTE_24H_UP | 177 | 7 | 17377 | 282 |
C2orf88,SATB2,DLX2,COLEC10,BACE1,TIAM2,PGBD5 |
| 2.567e-02 | -3.66 | GSE46242_CTRL_VS_EGR2_DELETED_ANERGIC_TH1_CD4_TCELL_UP | MSigDB lists | GSE46242_CTRL_VS_EGR2_DELETED_ANERGIC_TH1_CD4_TCELL_UP | 177 | 7 | 17377 | 282 |
TMEM53,DISP1,ARRDC4,ABHD4,KLHL3,BLVRB,ALDOA |
| 2.567e-02 | -3.66 | GSE21360_TERTIARY_VS_QUATERNARY_MEMORY_CD8_TCELL_UP | MSigDB lists | GSE21360_TERTIARY_VS_QUATERNARY_MEMORY_CD8_TCELL_UP | 177 | 7 | 17377 | 282 |
ARL2,CEBPA,PDE4D,NCEH1,VGLL4,SMPDL3A,ZDHHC23 |
| 2.567e-02 | -3.66 | GO_REGULATION_OF_PROTEIN_IMPORT | MSigDB lists | GO_REGULATION_OF_PROTEIN_IMPORT | 177 | 7 | 17377 | 282 |
DAB2IP,MXI1,GAS6,DACT1,PRKCD,WWTR1,PKIA |
| 2.567e-02 | -3.66 | GSE41176_UNSTIM_VS_ANTI_IGM_STIM_TAK1_KO_BCELL_3H_UP | MSigDB lists | GSE41176_UNSTIM_VS_ANTI_IGM_STIM_TAK1_KO_BCELL_3H_UP | 177 | 7 | 17377 | 282 |
ARRDC4,RASAL2,STXBP1,KLHL23,TBC1D16,PFN2,ZIC5 |
| 2.575e-02 | -3.66 | RasGAP | smart domains | SM00323 | 14 | 2 | 9493 | 172 |
DAB2IP,RASAL2 |
| 2.577e-02 | -3.66 | GO_NEGATIVE_REGULATION_OF_TRANSCRIPTION_FROM_RNA_POLYMERASE_II_PROMOTER | MSigDB lists | GO_NEGATIVE_REGULATION_OF_TRANSCRIPTION_FROM_RNA_POLYMERASE_II_PROMOTER | 719 | 19 | 17377 | 282 |
MSX1,ZHX3,WWC1,SATB2,CEBPA,PRDM1,ACVR2B,ZNF219,SATB1,RERE,TRIB3,WFS1,MYC,DACT1,WWTR1,DAB2IP,DLX2,PKIA,DDIT3 |
| 2.578e-02 | -3.66 | PID_MTOR_4PATHWAY | MSigDB lists | PID_MTOR_4PATHWAY | 69 | 4 | 17377 | 282 |
SGK1,BNIP3,PXN,PRKCA |
| 2.586e-02 | -3.66 | regulation of calcium ion transmembrane transport | biological process | GO:1903169 | 144 | 6 | 17256 | 270 |
PDE4D,CACNB4,PTPN6,HSPA2,UBASH3B,EHD3 |
| 2.603e-02 | -3.65 | YWHAB (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta) | protein interactions | 7529 | 381 | 12 | 17029 | 283 |
PHLDB2,RALGPS2,RASAL2,KIAA0355,DACT1,MYC,PRKCD,SPATA13,ACTA2,WWC1,TANC2,RADIL |
| 2.605e-02 | -3.65 | human chr11q13.5 | chromosome location | human chr11q13.5 | 20 | 2 | 26185 | 331 |
WNT11,CAPN5 |
| 2.606e-02 | -3.65 | p38 MAPK Signaling Pathway | WikiPathways | WP400 | 34 | 3 | 5312 | 101 |
MAP2K6,MYC,DDIT3 |
| 2.617e-02 | -3.64 | microtubule associated complex | cellular component | GO:0005875 | 147 | 6 | 18223 | 280 |
MAP7,KIF5C,PXN,KIF21B,DYNC1I1,DNAH5 |
| 2.627e-02 | -3.64 | GO_REGULATION_OF_SEQUESTERING_OF_CALCIUM_ION | MSigDB lists | GO_REGULATION_OF_SEQUESTERING_OF_CALCIUM_ION | 103 | 5 | 17377 | 282 |
PDE4D,ITPR2,UBASH3B,PTPN6,DDIT3 |
| 2.627e-02 | -3.64 | GROSS_HYPOXIA_VIA_HIF1A_DN | MSigDB lists | GROSS_HYPOXIA_VIA_HIF1A_DN | 103 | 5 | 17377 | 282 |
SGK1,BNIP3,GAPDH,PNRC1,TIAM2 |
| 2.631e-02 | -3.64 | diffuse_adenocarcinoma | COSMIC cancer mutations | diffuse_adenocarcinoma | 4468 | 87 | 17385 | 281 |
ARHGAP26,ACSL1,ZNF516,DOCK1,ST14,PTPN21,NRN1,SLC2A13,ABAT,COLEC10,KIF21B,CACNB4,RADIL,HMCN1,TIAM2,EPDR1,CPNE2,ZNF827,KCTD15,DLX6,DACT1,ZNF521,ZDHHC23,MAP7,MYH15,TLN2,DNAH5,TSHR,FANK1,TBC1D8,C3orf67,DZANK1,KLHL23,KLHL3,SLC39A8,DSTN,NLGN4X,SATB2,TNS1,SPNS1,LMLN,ANKRD31,RASGRF2,WWTR1,PLEKHG1,ARHGAP28,DISP1,COBL,GPR63,SCN5A,MXI1,NECAB2,ZNF395,SCART1,ARHGEF11,BVES,CCNJL,SETBP1,DYNC1I1,FHOD3,MTUS1,NEO1,ZIC5,SRGAP1,TRIM3,PRICKLE2,CCDC122,KIAA0408,STXBP1,BARX1,GPR161,PARP9,EPB41L5,SLC40A1,MPP1,WDR25,WWC1,LHPP,GPR137C,CTIF,KIAA0355,ADAMTS3,LRRIQ3,CLMN,ZNF474,SMYD3,PKIA |
| 2.631e-02 | -3.64 | stomach-carcinoma-diffuse_adenocarcinoma | COSMIC cancer mutations | stomach-carcinoma-diffuse_adenocarcinoma | 4468 | 87 | 17385 | 281 |
ARHGAP26,ACSL1,ZNF516,DOCK1,ST14,PTPN21,NRN1,SLC2A13,ABAT,COLEC10,KIF21B,CACNB4,RADIL,HMCN1,TIAM2,EPDR1,CPNE2,ZNF827,KCTD15,DLX6,DACT1,ZNF521,ZDHHC23,MAP7,MYH15,TLN2,DNAH5,TSHR,FANK1,TBC1D8,C3orf67,DZANK1,KLHL23,KLHL3,SLC39A8,DSTN,NLGN4X,SATB2,TNS1,SPNS1,LMLN,ANKRD31,RASGRF2,WWTR1,PLEKHG1,ARHGAP28,DISP1,COBL,GPR63,SCN5A,MXI1,NECAB2,ZNF395,SCART1,ARHGEF11,BVES,CCNJL,SETBP1,DYNC1I1,FHOD3,MTUS1,NEO1,ZIC5,SRGAP1,TRIM3,PRICKLE2,CCDC122,KIAA0408,STXBP1,BARX1,GPR161,PARP9,EPB41L5,SLC40A1,MPP1,WDR25,WWC1,LHPP,GPR137C,CTIF,KIAA0355,ADAMTS3,LRRIQ3,CLMN,ZNF474,SMYD3,PKIA |
| 2.631e-02 | -3.64 | vascular endothelial growth factor receptor signaling pathway | biological process | GO:0048010 | 72 | 4 | 17256 | 270 |
MAPK13,DAB2IP,PXN,DOCK1 |
| 2.637e-02 | -3.64 | GSE5589_IL6_KO_VS_IL10_KO_LPS_STIM_MACROPHAGE_180MIN_DN | MSigDB lists | GSE5589_IL6_KO_VS_IL10_KO_LPS_STIM_MACROPHAGE_180MIN_DN | 178 | 7 | 17377 | 282 |
SLC40A1,PRKCD,SMPDL3A,GPR161,PARP9,TBC1D8,NUAK2 |
| 2.637e-02 | -3.64 | GSE22886_CD4_TCELL_VS_BCELL_NAIVE_DN | MSigDB lists | GSE22886_CD4_TCELL_VS_BCELL_NAIVE_DN | 178 | 7 | 17377 | 282 |
SETBP1,COLEC10,MOXD1,FBXO4,NIPSNAP3B,EHD3,TIAM2 |
| 2.637e-02 | -3.64 | GSE15735_CTRL_VS_HDAC_INHIBITOR_TREATED_CD4_TCELL_12H_UP | MSigDB lists | GSE15735_CTRL_VS_HDAC_INHIBITOR_TREATED_CD4_TCELL_12H_UP | 178 | 7 | 17377 | 282 |
ARHGAP26,PPM1E,PJA1,MARVELD2,KIAA1549,CAPN5,ALDOA |
| 2.637e-02 | -3.64 | GSE46606_UNSTIM_VS_CD40L_IL2_IL5_DAY3_STIMULATED_BCELL_UP | MSigDB lists | GSE46606_UNSTIM_VS_CD40L_IL2_IL5_DAY3_STIMULATED_BCELL_UP | 178 | 7 | 17377 | 282 |
THAP10,APBA2,MARVELD2,GPR155,SMYD3,PLXNA2,C3orf67 |
| 2.637e-02 | -3.64 | GSE30971_CTRL_VS_LPS_STIM_MACROPHAGE_WBP7_HET_2H_DN | MSigDB lists | GSE30971_CTRL_VS_LPS_STIM_MACROPHAGE_WBP7_HET_2H_DN | 178 | 7 | 17377 | 282 |
KIAA0513,ABHD6,MPP1,UBASH3B,BLVRB,RERE,EEPD1 |
| 2.640e-02 | -3.63 | CUI_TCF21_TARGETS_2_DN | MSigDB lists | CUI_TCF21_TARGETS_2_DN | 770 | 20 | 17377 | 282 |
ARHGAP26,TMC7,CCDC126,BACE1,ADCY1,MAFB,SLC36A4,PRDM1,PALLD,PRKCA,MTUS1,IGIP,KIAA0355,EHD3,WWTR1,PLEKHG1,SGK1,ARHGAP28,MYOM2,PDE4D |
| 2.642e-02 | -3.63 | RNGTGGGC_UNKNOWN | MSigDB lists | RNGTGGGC_UNKNOWN | 721 | 19 | 17377 | 282 |
BDNF,MXI1,CCDC148,GAPDH,PTPN6,SATB2,OVOL2,DYNC1I1,NT5DC2,RERE,RGS17,PPM1E,KCTD15,RALGPS2,ADAMTS3,ALDOA,EPHB6,DBP,COBL |
| 2.642e-02 | -3.63 | GO_NEURON_PROJECTION_MORPHOGENESIS | MSigDB lists | GO_NEURON_PROJECTION_MORPHOGENESIS | 391 | 12 | 17377 | 282 |
BDNF,NUMBL,ADCY1,PLXNA2,EFNA3,SGK1,KIF5C,DAB2IP,STXBP1,COBL,NEO1,RERE |
| 2.645e-02 | -3.63 | positive regulation of protein ubiquitination | biological process | GO:0031398 | 107 | 5 | 17256 | 270 |
INAVA,TRIB3,ARRDC4,FBXO4,WFS1 |
| 2.652e-02 | -3.63 | ACTC1 (actin, alpha, cardiac muscle 1) | protein interactions | 70 | 68 | 4 | 17029 | 283 |
ACTA2,GAPDH,COBL,MYC |
| 2.652e-02 | -3.63 | DENND4C (DENN domain containing 4C) | protein interactions | 55667 | 68 | 4 | 17029 | 283 |
PHLDB2,RALGPS2,RASAL2,TANC2 |
| 2.666e-02 | -3.62 | TP53 Regulates Transcription of Cell Death Genes | REACTOME pathways | R-HSA-5633008 | 45 | 3 | 10287 | 148 |
TNFRSF10C,PMAIP1,BNIP3L |
| 2.669e-02 | -3.62 | negative regulation of transcription, DNA-templated | biological process | GO:0045892 | 1166 | 27 | 17256 | 270 |
RUNX2,MSX1,MXI1,LGR4,ZHX3,WWC1,SATB2,WNT11,CEBPA,PRDM1,GAS6,ACVR2B,OVOL2,ZNF219,SATB1,RERE,TRIB3,DACT1,WFS1,MYC,WWTR1,DAB2IP,DLX2,KCTD1,PKIA,DDIT3,PARP9 |
| 2.678e-02 | -3.62 | GO_CARDIAC_CHAMBER_DEVELOPMENT | MSigDB lists | GO_CARDIAC_CHAMBER_DEVELOPMENT | 140 | 6 | 17377 | 282 |
WNT11,SCN5A,PRDM1,ACVR1,OVOL2,SAV1 |
| 2.678e-02 | -3.62 | GO_PLATELET_ACTIVATION | MSigDB lists | GO_PLATELET_ACTIVATION | 140 | 6 | 17377 | 282 |
ITPR2,GAS6,PRKCA,STXBP1,PTPN6,PRKCD |
| 2.678e-02 | -3.62 | ATM_DN.V1_UP | MSigDB lists | ATM_DN.V1_UP | 140 | 6 | 17377 | 282 |
BDNF,LHPP,APBA2,DLX6,SOX21,TIAM2 |
| 2.683e-02 | -3.62 | nucleotide binding | molecular function | GO:0000166 | 2092 | 45 | 17224 | 278 |
RUNX2,ACSL1,ACVR1,BVES,ARL2,KIF5C,RASL11B,KIF21B,PRKCA,KMO,RPS6KL1,PRKCD,RASD2,EHD3,GTF2F2,ACTA2,SGK1,MYH15,PDE4D,EPHB6,RAB27B,DNAH5,HSPA2,PARP9,GAPDH,PDK1,CYB5R2,NUAK2,ADCY1,STRADB,ABCC2,RAB38,ACVR2B,SGK2,GRK3,DYRK1B,TRIB3,FGR,PLK2,MAP2K6,GNAO1,FMO4,ERN1,HK2,MAPK13 |
| 2.684e-02 | -3.62 | protein kinase C activity | molecular function | GO:0004697 | 16 | 2 | 17224 | 278 |
PRKCA,PRKCD |
| 2.684e-02 | -3.62 | protein-hormone receptor activity | molecular function | GO:0016500 | 16 | 2 | 17224 | 278 |
LGR4,TSHR |
| 2.685e-02 | -3.62 | rhabdomyosarcoma | COSMIC cancer mutations | rhabdomyosarcoma | 4239 | 83 | 17385 | 281 |
ARHGAP26,ACSL1,ZNF516,DOCK1,FAM131C,CEBPA,SLC2A13,COLEC10,RADIL,HMCN1,TIAM2,EPDR1,ZNF827,PPM1E,KMO,TMEM143,EEPD1,MYH15,TLN2,DNAH5,TSHR,TBC1D8,GAPDH,PNRC1,KLHL23,SLC39A8,PTPN6,CAPN5,NLGN4X,SATB2,WNT11,ABCC2,PLEKHA1,CENPV,DYRK1B,TCF7L1,PLK2,WFS1,ERN1,PLEKHG1,MAPK13,DISP1,KLHL31,TANC2,APBA2,COBL,TMEM63C,SCN5A,TMEM132C,SCART1,ARHGEF11,ZHX3,CYP2J2,ARL2,PFN2,FHOD3,MTUS1,NEO1,NUMBL,GPR155,ZIC5,GAN,EBF4,PRICKLE2,KIAA0408,MOXD1,VGLL4,PARP9,MN1,IL17RD,EFNA3,SPATA13,WWC1,PRDM1,B4GALNT3,RERE,ADAMTS3,EMILIN2,HK2,MYOM2,ZNF474,TNFRSF17,PHC1 |
| 2.686e-02 | -3.62 | GO_NEGATIVE_REGULATION_OF_FAT_CELL_DIFFERENTIATION | MSigDB lists | GO_NEGATIVE_REGULATION_OF_FAT_CELL_DIFFERENTIATION | 40 | 3 | 17377 | 282 |
TRIB3,DDIT3,WWTR1 |
| 2.686e-02 | -3.62 | ASGHARZADEH_NEUROBLASTOMA_POOR_SURVIVAL_DN | MSigDB lists | ASGHARZADEH_NEUROBLASTOMA_POOR_SURVIVAL_DN | 40 | 3 | 17377 | 282 |
TMOD2,APBA2,ADCY1 |
| 2.700e-02 | -3.61 | chr18q21 | MSigDB lists | chr18q21 | 70 | 4 | 17377 | 282 |
SETBP1,RAB27B,PMAIP1,CTIF |
| 2.700e-02 | -3.61 | GO_ENDOTHELIAL_CELL_DIFFERENTIATION | MSigDB lists | GO_ENDOTHELIAL_CELL_DIFFERENTIATION | 70 | 4 | 17377 | 282 |
ACVR2B,ACVR1,PDE4D,MARVELD2 |
| 2.700e-02 | -3.61 | GNF2_TAL1 | MSigDB lists | GNF2_TAL1 | 70 | 4 | 17377 | 282 |
HEBP1,MPP1,BLVRB,BNIP3L |
| 2.700e-02 | -3.61 | chr3q13 | MSigDB lists | chr3q13 | 70 | 4 | 17377 | 282 |
PHLDB2,MYH15,PARP9,ZDHHC23 |
| 2.700e-02 | -3.61 | GCM_DLG1 | MSigDB lists | GCM_DLG1 | 70 | 4 | 17377 | 282 |
PLEKHA1,ABHD6,NCS1,PLEKHB1 |
| 2.700e-02 | -3.61 | LEE_METASTASIS_AND_ALTERNATIVE_SPLICING_UP | MSigDB lists | LEE_METASTASIS_AND_ALTERNATIVE_SPLICING_UP | 70 | 4 | 17377 | 282 |
NLGN4X,BNIP3,RPS6KL1,PLXNA2 |
| 2.702e-02 | -3.61 | nucleoside phosphate binding | molecular function | GO:1901265 | 2093 | 45 | 17224 | 278 |
RUNX2,ACSL1,ACVR1,BVES,ARL2,KIF5C,RASL11B,KIF21B,PRKCA,KMO,RPS6KL1,PRKCD,RASD2,EHD3,GTF2F2,ACTA2,SGK1,MYH15,PDE4D,EPHB6,RAB27B,DNAH5,HSPA2,PARP9,GAPDH,PDK1,CYB5R2,NUAK2,ADCY1,STRADB,ABCC2,RAB38,ACVR2B,SGK2,GRK3,DYRK1B,TRIB3,FGR,PLK2,MAP2K6,GNAO1,FMO4,ERN1,HK2,MAPK13 |
| 2.705e-02 | -3.61 | Serotonin Neurotransmitter Release Cycle | REACTOME pathways | R-HSA-181429 | 18 | 2 | 10287 | 148 |
PPFIA4,STXBP1 |
| 2.705e-02 | -3.61 | Norepinephrine Neurotransmitter Release Cycle | REACTOME pathways | R-HSA-181430 | 18 | 2 | 10287 | 148 |
PPFIA4,STXBP1 |
| 2.708e-02 | -3.61 | GSE40666_UNTREATED_VS_IFNA_STIM_STAT1_KO_CD8_TCELL_90MIN_DN | MSigDB lists | GSE40666_UNTREATED_VS_IFNA_STIM_STAT1_KO_CD8_TCELL_90MIN_DN | 179 | 7 | 17377 | 282 |
STRADB,PHLDB2,PLEKHA1,SAV1,ZHX3,KIAA0355,SLC39A8 |
| 2.708e-02 | -3.61 | TGFB_UP.V1_DN | MSigDB lists | TGFB_UP.V1_DN | 179 | 7 | 17377 | 282 |
MN1,RAB38,SAV1,ZNF395,LGR4,PLXNA2,PGBD5 |
| 2.708e-02 | -3.61 | GSE36888_UNTREATED_VS_IL2_TREATED_TCELL_17H_DN | MSigDB lists | GSE36888_UNTREATED_VS_IL2_TREATED_TCELL_17H_DN | 179 | 7 | 17377 | 282 |
MN1,ACSL1,ZNF697,TBC1D16,SLC39A8,CYB5R2,SMPDL3A |
| 2.708e-02 | -3.61 | GSE12845_IGD_POS_VS_NEG_BLOOD_BCELL_UP | MSigDB lists | GSE12845_IGD_POS_VS_NEG_BLOOD_BCELL_UP | 179 | 7 | 17377 | 282 |
SCN5A,PLEKHA1,ZNF516,SATB1,KMO,PHC1,ADCY1 |
| 2.708e-02 | -3.61 | GSE10325_LUPUS_CD4_TCELL_VS_LUPUS_BCELL_UP | MSigDB lists | GSE10325_LUPUS_CD4_TCELL_VS_LUPUS_BCELL_UP | 179 | 7 | 17377 | 282 |
KIAA0513,ACVR1,PXN,PRKCA,KIF21B,APBA2,PLEKHB1 |
| 2.708e-02 | -3.61 | GSE20152_SPHK1_KO_VS_WT_HTNFA_OVERXPRESS_ANKLE_DN | MSigDB lists | GSE20152_SPHK1_KO_VS_WT_HTNFA_OVERXPRESS_ANKLE_DN | 179 | 7 | 17377 | 282 |
KIAA0513,WDR25,NDRG2,SLC25A28,PLEKHA1,BNIP3L,EFNA3 |
| 2.708e-02 | -3.61 | GSE13411_IGM_MEMORY_BCELL_VS_PLASMA_CELL_DN | MSigDB lists | GSE13411_IGM_MEMORY_BCELL_VS_PLASMA_CELL_DN | 179 | 7 | 17377 | 282 |
KIAA0513,NRN1,PRDM1,TNFRSF17,TSHR,HPCAL4,NT5DC2 |
| 2.708e-02 | -3.61 | GSE13306_RA_VS_UNTREATED_MEM_CD4_TCELL_DN | MSigDB lists | GSE13306_RA_VS_UNTREATED_MEM_CD4_TCELL_DN | 179 | 7 | 17377 | 282 |
TRIB3,PHLDB2,IFT81,PRDM1,PDK1,SCAMP1,NIPSNAP3B |
| 2.708e-02 | -3.61 | GSE2770_IL12_AND_TGFB_ACT_VS_ACT_CD4_TCELL_6H_UP | MSigDB lists | GSE2770_IL12_AND_TGFB_ACT_VS_ACT_CD4_TCELL_6H_UP | 179 | 7 | 17377 | 282 |
EPHB6,RAB38,APBA2,ABHD4,SMYD3,TBC1D8,PHC1 |
| 2.708e-02 | -3.61 | GSE13229_IMM_VS_INTMATURE_NKCELL_UP | MSigDB lists | GSE13229_IMM_VS_INTMATURE_NKCELL_UP | 179 | 7 | 17377 | 282 |
SHISA2,FGR,PDK1,TLR6,RADIL,KIAA1549,GPR161 |
| 2.708e-02 | -3.61 | GSE22886_NAIVE_CD4_TCELL_VS_NKCELL_UP | MSigDB lists | GSE22886_NAIVE_CD4_TCELL_VS_NKCELL_UP | 179 | 7 | 17377 | 282 |
KIF5C,EPHB6,PRKCA,MPP1,PLEKHB1,PKIA,RERE |
| 2.708e-02 | -3.61 | GSE14308_TH1_VS_NAIVE_CD4_TCELL_UP | MSigDB lists | GSE14308_TH1_VS_NAIVE_CD4_TCELL_UP | 179 | 7 | 17377 | 282 |
MAPK13,SLC36A4,CACNB4,SMYD3,ERN1,BIK,TMEM143 |
| 2.711e-02 | -3.61 | GO_MITOGEN_ACTIVATED_PROTEIN_KINASE_KINASE_BINDING | MSigDB lists | GO_MITOGEN_ACTIVATED_PROTEIN_KINASE_KINASE_BINDING | 16 | 2 | 17377 | 282 |
DAB2IP,TRIB3 |
| 2.711e-02 | -3.61 | GO_PROTEIN_KINASE_C_ACTIVITY | MSigDB lists | GO_PROTEIN_KINASE_C_ACTIVITY | 16 | 2 | 17377 | 282 |
PRKCA,PRKCD |
| 2.711e-02 | -3.61 | GO_NEGATIVE_REGULATION_OF_STEM_CELL_PROLIFERATION | MSigDB lists | GO_NEGATIVE_REGULATION_OF_STEM_CELL_PROLIFERATION | 16 | 2 | 17377 | 282 |
WNT11,OVOL2 |
| 2.711e-02 | -3.61 | GO_PARAXIAL_MESODERM_DEVELOPMENT | MSigDB lists | GO_PARAXIAL_MESODERM_DEVELOPMENT | 16 | 2 | 17377 | 282 |
EPB41L5,WNT11 |
| 2.711e-02 | -3.61 | REACTOME_PLATELET_SENSITIZATION_BY_LDL | MSigDB lists | REACTOME_PLATELET_SENSITIZATION_BY_LDL | 16 | 2 | 17377 | 282 |
FGR,PTPN6 |
| 2.711e-02 | -3.61 | GO_INTESTINAL_EPITHELIAL_CELL_DIFFERENTIATION | MSigDB lists | GO_INTESTINAL_EPITHELIAL_CELL_DIFFERENTIATION | 16 | 2 | 17377 | 282 |
PRDM1,SAV1 |
| 2.711e-02 | -3.61 | BIOCARTA_CDMAC_PATHWAY | MSigDB lists | BIOCARTA_CDMAC_PATHWAY | 16 | 2 | 17377 | 282 |
PRKCA,MYC |
| 2.711e-02 | -3.61 | GO_TRANSMEMBRANE_RECEPTOR_PROTEIN_SERINE_THREONINE_KINASE_ACTIVITY | MSigDB lists | GO_TRANSMEMBRANE_RECEPTOR_PROTEIN_SERINE_THREONINE_KINASE_ACTIVITY | 16 | 2 | 17377 | 282 |
ACVR2B,ACVR1 |
| 2.711e-02 | -3.61 | REACTOME_REGULATION_OF_KIT_SIGNALING | MSigDB lists | REACTOME_REGULATION_OF_KIT_SIGNALING | 16 | 2 | 17377 | 282 |
PRKCA,PTPN6 |
| 2.711e-02 | -3.61 | GO_CHLORIDE_CHANNEL_REGULATOR_ACTIVITY | MSigDB lists | GO_CHLORIDE_CHANNEL_REGULATOR_ACTIVITY | 16 | 2 | 17377 | 282 |
SGK1,SGK2 |
| 2.715e-02 | -3.61 | ATGTACA,MIR-493 | MSigDB lists | ATGTACA,MIR-493 | 304 | 10 | 17377 | 282 |
RASAL2,SOX21,ADCY1,EFNA3,RASL11B,DAB2IP,PDE4D,VGLL4,PFN2,FHOD3 |
| 2.724e-02 | -3.60 | MODULE_157 | MSigDB lists | MODULE_157 | 104 | 5 | 17377 | 282 |
RGS16,FGR,ABAT,STXBP1,EFNA3 |
| 2.724e-02 | -3.60 | REACTOME_SIGNALING_BY_EGFR_IN_CANCER | MSigDB lists | REACTOME_SIGNALING_BY_EGFR_IN_CANCER | 104 | 5 | 17377 | 282 |
TRIB3,ITPR2,PRKCA,PRKCD,ADCY1 |
| 2.724e-02 | -3.60 | HALLMARK_PI3K_AKT_MTOR_SIGNALING | MSigDB lists | HALLMARK_PI3K_AKT_MTOR_SIGNALING | 104 | 5 | 17377 | 282 |
TRIB3,ITPR2,PDK1,MAP2K6,DDIT3 |
| 2.741e-02 | -3.60 | nucleoside phosphate biosynthetic process | biological process | GO:1901293 | 228 | 8 | 17256 | 270 |
GAPDH,KMO,ALDOA,ADCY1,OGDHL,HK2,LHPP,PARP9 |
| 2.741e-02 | -3.60 | regulation of transmembrane receptor protein serine/threonine kinase signaling pathway | biological process | GO:0090092 | 228 | 8 | 17256 | 270 |
MSX1,ACVR1,DACT1,RBPMS2,WWTR1,RASL11B,ACVR2B,NEO1 |
| 2.748e-02 | -3.59 | proton-transporting two-sector ATPase complex, catalytic domain | cellular component | GO:0033178 | 17 | 2 | 18223 | 280 |
ATP6V1E2,ATP6AP1L |
| 2.751e-02 | -3.59 | cellular response to calcium ion | biological process | GO:0071277 | 73 | 4 | 17256 | 270 |
CPNE2,SCN5A,ADCY1,GPLD1 |
| 2.751e-02 | -3.59 | ATP biosynthetic process | biological process | GO:0006754 | 73 | 4 | 17256 | 270 |
GAPDH,ALDOA,OGDHL,HK2 |
| 2.751e-02 | -3.59 | SENESE_HDAC1_AND_HDAC2_TARGETS_UP | MSigDB lists | SENESE_HDAC1_AND_HDAC2_TARGETS_UP | 220 | 8 | 17377 | 282 |
PXN,UBASH3B,RBPMS2,CAPN5,WWC1,PDE4D,PRDM1,JAM3 |
| 2.759e-02 | -3.59 | haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-NK-T_cell_lymphoma | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-NK-T_cell_lymphoma | 221 | 8 | 17385 | 281 |
P4HA1,WWC1,BNIP3,PRDM1,FAM198B,DNAH5,SRGAP1,PLXNA2 |
| 2.766e-02 | -3.59 | PTB/PI_dom | interpro domains | IPR006020 | 41 | 3 | 18492 | 296 |
TNS1,NUMBL,APBA2 |
| 2.777e-02 | -3.58 | apical junction assembly | biological process | GO:0043297 | 42 | 3 | 17256 | 270 |
ARL2,WNT11,MARVELD2 |
| 2.780e-02 | -3.58 | GSE26290_WT_VS_PDK1_KO_ANTI_CD3_AND_IL2_STIM_CD8_TCELL_UP | MSigDB lists | GSE26290_WT_VS_PDK1_KO_ANTI_CD3_AND_IL2_STIM_CD8_TCELL_UP | 180 | 7 | 17377 | 282 |
NRN1,PRDM1,ACSL1,SFXN4,ISM1,PRKCD,CENPV |
| 2.780e-02 | -3.58 | GSE6674_CPG_VS_CPG_AND_ANTI_IGM_STIM_BCELL_DN | MSigDB lists | GSE6674_CPG_VS_CPG_AND_ANTI_IGM_STIM_BCELL_DN | 180 | 7 | 17377 | 282 |
P4HA1,TRIB3,MXI1,SMYD3,MYC,DDIT3,HK2 |
| 2.780e-02 | -3.58 | GSE13485_DAY3_VS_DAY21_YF17D_VACCINE_PBMC_UP | MSigDB lists | GSE13485_DAY3_VS_DAY21_YF17D_VACCINE_PBMC_UP | 180 | 7 | 17377 | 282 |
KIAA0513,SPNS1,SLC25A28,ZNF516,HERC6,EMILIN2,TBC1D8 |
| 2.780e-02 | -3.58 | GSE27241_CTRL_VS_DIGOXIN_TREATED_RORGT_KO_CD4_TCELL_IN_TH17_POLARIZING_CONDITIONS_UP | MSigDB lists | GSE27241_CTRL_VS_DIGOXIN_TREATED_RORGT_KO_CD4_TCELL_IN_TH17_POLARIZING_CONDITIONS_UP | 180 | 7 | 17377 | 282 |
ABCC2,RALGPS2,TSHR,MAP2K6,CENPV,PLEKHG1,EEPD1 |
| 2.780e-02 | -3.58 | ESC_V6.5_UP_LATE.V1_UP | MSigDB lists | ESC_V6.5_UP_LATE.V1_UP | 180 | 7 | 17377 | 282 |
P4HA1,RASAL2,SATB1,BVES,RECK,SLC39A8,ZNF521 |
| 2.783e-02 | -3.58 | adenyl ribonucleotide binding | molecular function | GO:0032559 | 1502 | 34 | 17224 | 278 |
RUNX2,ACSL1,ACVR1,BVES,KIF5C,KIF21B,PRKCA,RPS6KL1,PRKCD,EHD3,GTF2F2,ACTA2,SGK1,MYH15,PDE4D,EPHB6,DNAH5,HSPA2,PDK1,NUAK2,ADCY1,STRADB,ABCC2,ACVR2B,SGK2,GRK3,DYRK1B,TRIB3,FGR,MAP2K6,PLK2,ERN1,HK2,MAPK13 |
| 2.784e-02 | -3.58 | ANXA7 (annexin A7) | protein interactions | 310 | 138 | 6 | 17029 | 283 |
CPNE2,GAPDH,PRKCA,DYNC1I1,KLHL23,TIAM2 |
| 2.788e-02 | -3.58 | Muscle contraction | REACTOME pathways | R-HSA-397014 | 204 | 7 | 10287 | 148 |
ACTA2,SCN5A,TMOD2,ITPR2,PXN,CACNB4,WWTR1 |
| 2.794e-02 | -3.58 | human chr1q32.1 | chromosome location | human chr1q32.1 | 134 | 5 | 26185 | 331 |
PPFIA4,INAVA,MFSD4A,KIF21B,NUAK2 |
| 2.800e-02 | -3.58 | GO_MOLECULAR_FUNCTION_REGULATOR | MSigDB lists | GO_MOLECULAR_FUNCTION_REGULATOR | 1284 | 30 | 17377 | 282 |
ARHGAP26,RGS16,RASAL2,ARHGEF11,DOCK1,RECK,C4A,SPATA13,ARL2,WNT11,GAS6,SGK2,TBC1D16,PFN2,HPCAL4,TIAM2,GPLD1,RGS17,TRIB3,RALGPS2,RASGRF2,PRKCD,PLEKHG1,SRGAP1,ARHGAP28,SGK1,DAB2IP,IQSEC2,PKIA,TBC1D8 |
| 2.803e-02 | -3.57 | Regulation of insulin secretion | REACTOME pathways | R-HSA-422356 | 80 | 4 | 10287 | 148 |
ARL2,ITPR2,PRKCA,STXBP1 |
| 2.813e-02 | -3.57 | GO_REGULATION_OF_INTRACELLULAR_SIGNAL_TRANSDUCTION | MSigDB lists | GO_REGULATION_OF_INTRACELLULAR_SIGNAL_TRANSDUCTION | 1601 | 36 | 17377 | 282 |
ARHGAP26,RASAL2,DUSP8,ARHGEF11,NDRG2,GAS6,PRKCA,TIAM2,RALGPS2,PMAIP1,DACT1,MYC,RASD2,PRKCD,SRGAP1,DAB2IP,PDE4D,MSX1,PTPN6,SPATA13,WWC1,WNT11,PLEKHA1,TLR6,TRIB3,FGR,PLK2,RASGRF2,WFS1,MAP2K6,ERN1,PLEKHG1,ARHGAP28,TNFSF15,IQSEC2,DDIT3 |
| 2.816e-02 | -3.57 | MORF_TFDP2 | MSigDB lists | MORF_TFDP2 | 221 | 8 | 17377 | 282 |
IQCK,MSX1,RUNX2,DOCK1,PDE4D,TANC2,PLEKHB1,GPLD1 |
| 2.824e-02 | -3.57 | GO_REGULATION_OF_RHO_PROTEIN_SIGNAL_TRANSDUCTION | MSigDB lists | GO_REGULATION_OF_RHO_PROTEIN_SIGNAL_TRANSDUCTION | 105 | 5 | 17377 | 282 |
ARHGEF11,RASGRF2,TIAM2,SPATA13,PLEKHG1 |
| 2.824e-02 | -3.57 | GO_TRANSITION_METAL_ION_TRANSPORT | MSigDB lists | GO_TRANSITION_METAL_ION_TRANSPORT | 105 | 5 | 17377 | 282 |
ATP6V1E2,SLC40A1,SLC30A4,SLC39A8,ATOX1 |
| 2.824e-02 | -3.57 | GO_POSITIVE_REGULATION_OF_CYCLIC_NUCLEOTIDE_METABOLIC_PROCESS | MSigDB lists | GO_POSITIVE_REGULATION_OF_CYCLIC_NUCLEOTIDE_METABOLIC_PROCESS | 105 | 5 | 17377 | 282 |
PRKCA,TSHR,WFS1,GPR161,ADCY1 |
| 2.826e-02 | -3.57 | GNF2_SPTB | MSigDB lists | GNF2_SPTB | 71 | 4 | 17377 | 282 |
HEBP1,MPP1,BLVRB,BNIP3L |
| 2.826e-02 | -3.57 | GO_POSITIVE_REGULATION_OF_TRANSPORTER_ACTIVITY | MSigDB lists | GO_POSITIVE_REGULATION_OF_TRANSPORTER_ACTIVITY | 71 | 4 | 17377 | 282 |
SGK1,SGK2,HSPA2,PRKCD |
| 2.826e-02 | -3.57 | ROSS_AML_WITH_PML_RARA_FUSION | MSigDB lists | ROSS_AML_WITH_PML_RARA_FUSION | 71 | 4 | 17377 | 282 |
CLMN,ITPR2,STXBP1,PGBD5 |
| 2.826e-02 | -3.57 | GNF2_ANK1 | MSigDB lists | GNF2_ANK1 | 71 | 4 | 17377 | 282 |
HEBP1,MPP1,BLVRB,BNIP3L |
| 2.833e-02 | -3.56 | TFAP2B (transcription factor AP-2 beta) | protein interactions | 7021 | 16 | 2 | 17029 | 283 |
MYC,KCTD1 |
| 2.833e-02 | -3.56 | INHBA (inhibin subunit beta A) | protein interactions | 3624 | 16 | 2 | 17029 | 283 |
ACVR2B,ACVR1 |
| 2.833e-02 | -3.56 | MATK (megakaryocyte-associated tyrosine kinase) | protein interactions | 4145 | 16 | 2 | 17029 | 283 |
PXN,MYC |
| 2.833e-02 | -3.56 | BCL2A1 (BCL2 related protein A1) | protein interactions | 597 | 16 | 2 | 17029 | 283 |
PMAIP1,BIK |
| 2.833e-02 | -3.56 | ENG (endoglin) | protein interactions | 2022 | 16 | 2 | 17029 | 283 |
ACVR2B,ACVR1 |
| 2.833e-02 | -3.56 | POTEKP (POTE ankyrin domain family member K, pseudogene) | protein interactions | 440915 | 16 | 2 | 17029 | 283 |
LGR4,COBL |
| 2.833e-02 | -3.56 | STC2 (stanniocalcin 2) | protein interactions | 8614 | 16 | 2 | 17029 | 283 |
CCNJL,COLEC10 |
| 2.833e-02 | -3.56 | LDLRAD1 (low density lipoprotein receptor class A domain containing 1) | protein interactions | 388633 | 16 | 2 | 17029 | 283 |
BNIP3,BNIP3L |
| 2.834e-02 | -3.56 | protein metabolic process | biological process | GO:0019538 | 4335 | 82 | 17256 | 270 |
CCDC126,ACVR1,DUSP8,RASAL2,ST14,RECK,C4A,PTPN21,ALG1L,NRN1,COLEC10,PRKCA,FKBP9,PPM1E,PMAIP1,RPS6KL1,CFHR1,ZDHHC23,DAB2IP,PJA1,EPHB6,GAPDH,PDK1,KLHL23,KLHL3,PTPN6,CAPN5,BNIP3L,WNT11,PXYLP1,ACVR2B,RAB38,SGK2,GRK3,DYRK1B,LMLN,PLK2,RASGRF2,WFS1,ERN1,WWTR1,P4HA1,TNFSF15,MAPK13,DISP1,KLHL31,LONRF1,PRSS16,UBASH3B,FBXO4,BACE1,GAS6,HERC6,SATB1,KDM7A,NUMBL,MYC,PRKCD,GAN,SGK1,TRIM3,BNIP3,PARP9,IL17RD,QSOX1,ENAM,B3GLCT,NUAK2,STRADB,LHPP,ARRDC4,GPLD1,TRIB3,FGR,ADAMTS3,MAP2K6,QPCTL,RNF122,SMYD3,B4GALT7,DDIT3,PHC1 |
| 2.836e-02 | -3.56 | ribonucleoside monophosphate biosynthetic process | biological process | GO:0009156 | 109 | 5 | 17256 | 270 |
LHPP,GAPDH,ALDOA,OGDHL,HK2 |
| 2.842e-02 | -3.56 | iron ion transmembrane transport | biological process | GO:0034755 | 17 | 2 | 17256 | 270 |
SLC40A1,SLC25A28 |
| 2.842e-02 | -3.56 | regulation of vascular endothelial growth factor signaling pathway | biological process | GO:1900746 | 17 | 2 | 17256 | 270 |
DAB2IP,ADAMTS3 |
| 2.842e-02 | -3.56 | segment specification | biological process | GO:0007379 | 17 | 2 | 17256 | 270 |
MAFB,COBL |
| 2.842e-02 | -3.56 | linoleic acid metabolic process | biological process | GO:0043651 | 17 | 2 | 17256 | 270 |
ACSL1,CYP2J2 |
| 2.845e-02 | -3.56 | GO_MICROTUBULE_ASSOCIATED_COMPLEX | MSigDB lists | GO_MICROTUBULE_ASSOCIATED_COMPLEX | 142 | 6 | 17377 | 282 |
MAP7,KIF5C,PXN,KIF21B,DYNC1I1,DNAH5 |
| 2.845e-02 | -3.56 | GO_OXIDOREDUCTASE_ACTIVITY_ACTING_ON_PAIRED_DONORS_WITH_INCORPORATION_OR_REDUCTION_OF_MOLECULAR_OXYGEN | MSigDB lists | GO_OXIDOREDUCTASE_ACTIVITY_ACTING_ON_PAIRED_DONORS_WITH_INCORPORATION_OR_REDUCTION_OF_MOLECULAR_OXYGEN | 142 | 6 | 17377 | 282 |
P4HA1,MOXD1,KMO,FMO4,CYP2J2,CYP4V2 |
| 2.847e-02 | -3.56 | GO_ORGAN_MORPHOGENESIS | MSigDB lists | GO_ORGAN_MORPHOGENESIS | 826 | 21 | 17377 | 282 |
ENAM,SCN5A,SLC40A1,MSX1,ACVR1,RUNX2,LGR4,KLHL3,MAFB,SATB2,WNT11,PRDM1,ACVR2B,OVOL2,PLEKHA1,SAV1,DLX6,MYC,WWTR1,ACTA2,DLX2 |
| 2.853e-02 | -3.56 | GSE15750_DAY6_VS_DAY10_EFF_CD8_TCELL_DN | MSigDB lists | GSE15750_DAY6_VS_DAY10_EFF_CD8_TCELL_DN | 181 | 7 | 17377 | 282 |
ZNF827,DBP,TLN2,PRKCA,PFN2,EHD3,RERE |
| 2.853e-02 | -3.56 | GSE20152_HTNFA_OVERXPRESS_ANKLE_VS_CTRL_SPHK1_KO_ANKLE_UP | MSigDB lists | GSE20152_HTNFA_OVERXPRESS_ANKLE_VS_CTRL_SPHK1_KO_ANKLE_UP | 181 | 7 | 17377 | 282 |
CLMN,KCTD15,PXN,RECK,BARX1,CAPN5,PGBD5 |
| 2.853e-02 | -3.56 | GSE28130_ACTIVATED_VS_INDUCEED_TREG_UP | MSigDB lists | GSE28130_ACTIVATED_VS_INDUCEED_TREG_UP | 181 | 7 | 17377 | 282 |
RGS16,ABAT,RASAL2,PALLD,SLC39A8,MYC,SMPDL3A |
| 2.853e-02 | -3.56 | GSE29164_UNTREATED_VS_CD8_TCELL_AND_IL12_TREATED_MELANOMA_DAY3_UP | MSigDB lists | GSE29164_UNTREATED_VS_CD8_TCELL_AND_IL12_TREATED_MELANOMA_DAY3_UP | 181 | 7 | 17377 | 282 |
CCDC122,NDRG2,PPM1E,IQSEC2,EXOG,KIF21B,NCS1 |
| 2.853e-02 | -3.56 | GSE17721_CPG_VS_GARDIQUIMOD_8H_BMDC_DN | MSigDB lists | GSE17721_CPG_VS_GARDIQUIMOD_8H_BMDC_DN | 181 | 7 | 17377 | 282 |
NDRG2,PRDM1,SCAMP1,HSPA2,KCTD1,TBC1D8,PARP9 |
| 2.853e-02 | -3.56 | GSE27786_NKCELL_VS_ERYTHROBLAST_DN | MSigDB lists | GSE27786_NKCELL_VS_ERYTHROBLAST_DN | 181 | 7 | 17377 | 282 |
SPATA9,TMOD2,KCTD15,TMEM132C,WISP3,BIK,GPLD1 |
| 2.853e-02 | -3.56 | GSE11961_PLASMA_CELL_DAY7_VS_MEMORY_BCELL_DAY40_DN | MSigDB lists | GSE11961_PLASMA_CELL_DAY7_VS_MEMORY_BCELL_DAY40_DN | 181 | 7 | 17377 | 282 |
B9D1,LONRF1,MYOM2,ABCC2,DOCK1,NIPSNAP3B,RASGRF2 |
| 2.853e-02 | -3.56 | GSE40068_BCL6_POS_VS_NEG_CXCR5_POS_TFH_UP | MSigDB lists | GSE40068_BCL6_POS_VS_NEG_CXCR5_POS_TFH_UP | 181 | 7 | 17377 | 282 |
B9D1,ARHGAP26,FGR,RUNX2,ABHD4,GPR155,SMPDL3A |
| 2.853e-02 | -3.56 | GSE14308_NAIVE_CD4_TCELL_VS_NATURAL_TREG_UP | MSigDB lists | GSE14308_NAIVE_CD4_TCELL_VS_NATURAL_TREG_UP | 181 | 7 | 17377 | 282 |
SPNS1,ARL2,RALGPS2,ZHX3,BARX1,DLX6,EEPD1 |
| 2.853e-02 | -3.56 | GSE1432_CTRL_VS_IFNG_1H_MICROGLIA_DN | MSigDB lists | GSE1432_CTRL_VS_IFNG_1H_MICROGLIA_DN | 181 | 7 | 17377 | 282 |
RGS17,SATB2,RGS16,SAV1,PMAIP1,CACNB4,DACT1 |
| 2.854e-02 | -3.56 | DCAF5 (DDB1 and CUL4 associated factor 5) | protein interactions | 8816 | 40 | 3 | 17029 | 283 |
EPB41L5,PTPN21,NUAK2 |
| 2.854e-02 | -3.56 | MAP2K3 (mitogen-activated protein kinase kinase 3) | protein interactions | 5606 | 40 | 3 | 17029 | 283 |
DYRK1B,MAP2K6,MYC |
| 2.854e-02 | -3.56 | RHPN1 (rhophilin Rho GTPase binding protein 1) | protein interactions | 114822 | 40 | 3 | 17029 | 283 |
WWC1,IFT81,PTPN21 |
| 2.856e-02 | -3.56 | human chr2q14.2 | chromosome location | human chr2q14.2 | 21 | 2 | 26185 | 331 |
EPB41L5,TMEM37 |
| 2.856e-02 | -3.56 | human chr13q32.1 | chromosome location | human chr13q32.1 | 21 | 2 | 26185 | 331 |
SOX21,SOX21-AS1 |
| 2.857e-02 | -3.56 | Degradation of GABA | REACTOME pathways | R-HSA-916853 | 2 | 1 | 10287 | 148 |
ABAT |
| 2.857e-02 | -3.56 | Regulation of TP53 Expression | REACTOME pathways | R-HSA-6804754 | 2 | 1 | 10287 | 148 |
PRDM1 |
| 2.861e-02 | -3.55 | negative regulation of protein modification process | biological process | GO:0031400 | 604 | 16 | 17256 | 270 |
DUSP8,PTPN6,UBASH3B,NDRG2,CEBPA,PPM1E,TRIB3,MYC,DACT1,WWTR1,RASD2,PRKCD,DAB2IP,PDE4D,SMYD3,PKIA |
| 2.864e-02 | -3.55 | KERLEY_RESPONSE_TO_CISPLATIN_UP | MSigDB lists | KERLEY_RESPONSE_TO_CISPLATIN_UP | 41 | 3 | 17377 | 282 |
ACTA2,TNFRSF10C,PLK2 |
| 2.864e-02 | -3.55 | NAKAYAMA_FRA2_TARGETS | MSigDB lists | NAKAYAMA_FRA2_TARGETS | 41 | 3 | 17377 | 282 |
SGK1,DBP,LGR4 |
| 2.864e-02 | -3.55 | GO_PROTEIN_KINASE_A_BINDING | MSigDB lists | GO_PROTEIN_KINASE_A_BINDING | 41 | 3 | 17377 | 282 |
C2orf88,DACT1,PKIA |
| 2.864e-02 | -3.55 | PAPASPYRIDONOS_UNSTABLE_ATEROSCLEROTIC_PLAQUE_DN | MSigDB lists | PAPASPYRIDONOS_UNSTABLE_ATEROSCLEROTIC_PLAQUE_DN | 41 | 3 | 17377 | 282 |
TNS1,DSTN,JAM3 |
| 2.870e-02 | -3.55 | GIGYF2 (GRB10 interacting GYF protein 2) | protein interactions | 26058 | 103 | 5 | 17029 | 283 |
PHLDB2,RALGPS2,RASAL2,TANC2,LGR4 |
| 2.874e-02 | -3.55 | endothelial cell differentiation | biological process | GO:0045446 | 74 | 4 | 17256 | 270 |
ACVR2B,ACVR1,PDE4D,MARVELD2 |
| 2.874e-02 | -3.55 | positive regulation of interleukin-6 production | biological process | GO:0032755 | 74 | 4 | 17256 | 270 |
IL17D,INAVA,MAPK13,TLR6 |
| 2.876e-02 | -3.55 | regulation of cell migration | biological process | GO:0030334 | 858 | 21 | 17256 | 270 |
EPB41L5,PHLDB2,ACVR1,DOCK1,RECK,MPP1,SPATA13,PLXNA2,WNT11,GAS6,PRKCA,PFN2,ABHD6,JAM3,MTUS1,GPLD1,FGR,PLK2,SRGAP1,SGK1,DAB2IP |
| 2.876e-02 | -3.55 | Gluconeogenesis, oxaloacetate => fructose-6P | KEGG pathways | M00003 | 17 | 2 | 7161 | 113 |
GAPDH,ALDOA |
| 2.876e-02 | -3.55 | Gluconeogenesis, oxaloacetate => fructose-6P | KEGG pathways | hsa_M00003 | 17 | 2 | 7161 | 113 |
GAPDH,ALDOA |
| 2.877e-02 | -3.55 | GO_IN_UTERO_EMBRYONIC_DEVELOPMENT | MSigDB lists | GO_IN_UTERO_EMBRYONIC_DEVELOPMENT | 307 | 10 | 17377 | 282 |
B9D1,EPB41L5,MSX1,ACVR1,ST14,CEBPA,PRDM1,OVOL2,TANC2,APBA2 |
| 2.889e-02 | -3.54 | lung-carcinoma | COSMIC cancer mutations | lung-carcinoma | 4311 | 84 | 17385 | 281 |
ARHGAP26,ACVR1,DUSP8,DOCK1,PTPN21,ITPR2,SLC2A13,COLEC10,PRKCA,HMCN1,FKBP9,PPM1E,PMAIP1,DACT1,RPS6KL1,ZNF521,PDE4D,PJA1,RAB27B,OR2W3,HSPA2,GAPDH,PDK1,PTPN6,BNIP3L,NLGN4X,WNT11,ACVR2B,RAB38,PLEKHA1,SGK2,SAV1,PLEKHB1,DYRK1B,PLK2,RASGRF2,ERN1,ALDOA,TNFSF15,MAPK13,RGS16,MXI1,RUNX2,ARHGEF11,FBXO4,BIK,ARL2,GAS6,TNFRSF10C,DYNC1I1,SATB1,NUMBL,RGS17,RALGPS2,MYC,RASD2,PRKCD,SRGAP1,SGK1,TRIM3,BNIP3,TMC7,PXN,MPP1,SPATA13,NUAK2,STRADB,MAFB,PPFIA4,PRDM1,GPLD1,TRIB3,FGR,ADAMTS3,FMO4,MAP2K6,GNAO1,HK2,TNFRSF17,IQSEC2,RNF157,RNF122,SMYD3,DDIT3 |
| 2.892e-02 | -3.54 | GO_POSITIVE_REGULATION_OF_RESPONSE_TO_STIMULUS | MSigDB lists | GO_POSITIVE_REGULATION_OF_RESPONSE_TO_STIMULUS | 1819 | 40 | 17377 | 282 |
ACVR1,LGR4,DOCK1,C4A,BIK,ABAT,GAS6,COLEC10,PRKCA,CACNB4,NEO1,PMAIP1,CFHR1,DACT1,MYC,RASD2,PRKCD,DAB2IP,BNIP3,PDE4D,BDNF,MSX1,PTPN6,BNIP3L,WWC1,WNT11,PLEKHA1,ACVR2B,TLR6,GPLD1,FGR,ADAMTS3,MAP2K6,PLK2,ERN1,MAPK13,TMOD2,TNFSF15,DISP1,DDIT3 |
| 2.907e-02 | -3.54 | Thyroid hormone synthesis | KEGG pathways | hsa04918 | 74 | 4 | 7161 | 113 |
ITPR2,PRKCA,TSHR,ADCY1 |
| 2.907e-02 | -3.54 | Thyroid hormone synthesis | KEGG pathways | ko04918 | 74 | 4 | 7161 | 113 |
ITPR2,PRKCA,TSHR,ADCY1 |
| 2.909e-02 | -3.54 | Neuronal System | REACTOME pathways | R-HSA-112316 | 349 | 10 | 10287 | 148 |
EPB41L5,RASGRF2,ADCY1,NLGN4X,PPFIA4,ABAT,PRKCA,APBA2,STXBP1,CACNB4 |
| 2.911e-02 | -3.54 | GRK2 (G protein-coupled receptor kinase 2) | protein interactions | 156 | 70 | 4 | 17029 | 283 |
PRKCA,GRK3,PRKCD,NCS1 |
| 2.928e-02 | -3.53 | GSE23505_IL6_IL1_VS_IL6_IL1_TGFB_TREATED_CD4_TCELL_UP | MSigDB lists | GSE23505_IL6_IL1_VS_IL6_IL1_TGFB_TREATED_CD4_TCELL_UP | 182 | 7 | 17377 | 282 |
SPNS1,CCDC126,TNS1,DBP,ZNF516,TMEM120B,QPCTL |
| 2.928e-02 | -3.53 | MORF_BNIP1 | MSigDB lists | MORF_BNIP1 | 182 | 7 | 17377 | 282 |
IQCK,MSX1,ITPR2,RUNX2,SCAMP1,DOCK1,PLEKHB1 |
| 2.928e-02 | -3.53 | GSE19825_NAIVE_VS_IL2RAHIGH_DAY3_EFF_CD8_TCELL_UP | MSigDB lists | GSE19825_NAIVE_VS_IL2RAHIGH_DAY3_EFF_CD8_TCELL_UP | 182 | 7 | 17377 | 282 |
C2orf88,ACVR1,SATB1,ISM1,FMO4,TBC1D8,PGBD5 |
| 2.928e-02 | -3.53 | GSE37416_0H_VS_12H_F_TULARENSIS_LVS_NEUTROPHIL_DN | MSigDB lists | GSE37416_0H_VS_12H_F_TULARENSIS_LVS_NEUTROPHIL_DN | 182 | 7 | 17377 | 282 |
MXI1,PDK1,SAV1,ZNF395,DDIT3,BNIP3L,PHC1 |
| 2.928e-02 | -3.53 | KAECH_NAIVE_VS_DAY15_EFF_CD8_TCELL_UP | MSigDB lists | KAECH_NAIVE_VS_DAY15_EFF_CD8_TCELL_UP | 182 | 7 | 17377 | 282 |
P4HA1,PLEKHA1,PDK1,SLC30A4,SATB1,TLR6,MPP1 |
| 2.928e-02 | -3.53 | GSE3982_CENT_MEMORY_CD4_TCELL_VS_TH2_UP | MSigDB lists | GSE3982_CENT_MEMORY_CD4_TCELL_VS_TH2_UP | 182 | 7 | 17377 | 282 |
KIF5C,DZANK1,EPCAM,FKBP9,FAM198B,PNRC1,RASAL2 |
| 2.928e-02 | -3.53 | GSE20715_WT_VS_TLR4_KO_48H_OZONE_LUNG_DN | MSigDB lists | GSE20715_WT_VS_TLR4_KO_48H_OZONE_LUNG_DN | 182 | 7 | 17377 | 282 |
TRIM3,EPCAM,PLEKHA1,ALDOA,CENPV,PLEKHB1,PARP9 |
| 2.928e-02 | -3.53 | GSE37534_UNTREATED_VS_ROSIGLITAZONE_TREATED_CD4_TCELL_PPARG1_AND_FOXP3_TRASDUCED_DN | MSigDB lists | GSE37534_UNTREATED_VS_ROSIGLITAZONE_TREATED_CD4_TCELL_PPARG1_AND_FOXP3_TRASDUCED_DN | 182 | 7 | 17377 | 282 |
SETBP1,SLC25A28,MSX1,HERC6,SLC30A4,PMAIP1,HK2 |
| 2.928e-02 | -3.53 | GSE1460_CD4_THYMOCYTE_VS_THYMIC_STROMAL_CELL_DN | MSigDB lists | GSE1460_CD4_THYMOCYTE_VS_THYMIC_STROMAL_CELL_DN | 182 | 7 | 17377 | 282 |
FKBP9,IQCK,ADAMTS3,RECK,DACT1,BACE1,NT5DC2 |
| 2.928e-02 | -3.53 | GSE26343_WT_VS_NFAT5_KO_MACROPHAGE_LPS_STIM_DN | MSigDB lists | GSE26343_WT_VS_NFAT5_KO_MACROPHAGE_LPS_STIM_DN | 182 | 7 | 17377 | 282 |
ITPR2,GAS6,ABHD4,GPR155,MPP1,PLXNA2,BNIP3L |
| 2.928e-02 | -3.53 | GSE3203_INFLUENZA_INF_VS_IFNB_TREATED_LN_BCELL_DN | MSigDB lists | GSE3203_INFLUENZA_INF_VS_IFNB_TREATED_LN_BCELL_DN | 182 | 7 | 17377 | 282 |
B9D1,SLC36A4,LMLN,PLEKHA1,ACSL1,ST14,LSM11 |
| 2.928e-02 | -3.53 | GSE23925_LIGHT_ZONE_VS_DARK_ZONE_BCELL_DN | MSigDB lists | GSE23925_LIGHT_ZONE_VS_DARK_ZONE_BCELL_DN | 182 | 7 | 17377 | 282 |
SPNS1,MYOM2,IQCK,ZNF516,GAPDH,PLEKHA1,EHD3 |
| 2.928e-02 | -3.53 | GO_EPITHELIAL_CELL_DEVELOPMENT | MSigDB lists | GO_EPITHELIAL_CELL_DEVELOPMENT | 182 | 7 | 17377 | 282 |
EPB41L5,ACTA2,PRDM1,PDE4D,PALLD,ST14,MARVELD2 |
| 2.928e-02 | -3.53 | GSE36888_STAT5_AB_KNOCKIN_VS_WT_TCELL_IL2_TREATED_2H_UP | MSigDB lists | GSE36888_STAT5_AB_KNOCKIN_VS_WT_TCELL_IL2_TREATED_2H_UP | 182 | 7 | 17377 | 282 |
SGK1,CEBPA,MXI1,DBP,RAB38,MPP1,BACE1 |
| 2.928e-02 | -3.53 | GSE21774_CD56_BRIGHT_VS_DIM_CD62L_POSITIVE_NK_CELL_DN | MSigDB lists | GSE21774_CD56_BRIGHT_VS_DIM_CD62L_POSITIVE_NK_CELL_DN | 182 | 7 | 17377 | 282 |
EPB41L5,LHPP,UROS,HEBP1,BLVRB,EPDR1,PLXNA2 |
| 2.930e-02 | -3.53 | MODULE_238 | MSigDB lists | MODULE_238 | 143 | 6 | 17377 | 282 |
FGR,DBP,ZNF395,PNRC1,MAP2K6,PTPN6 |
| 2.930e-02 | -3.53 | GO_CELL_CYCLE_ARREST | MSigDB lists | GO_CELL_CYCLE_ARREST | 143 | 6 | 17377 | 282 |
STRADB,GAS6,MAP2K6,MYC,DDIT3,ERN1 |
| 2.930e-02 | -3.53 | regulation of calcium ion transport | biological process | GO:0051924 | 231 | 8 | 17256 | 270 |
PDE4D,CACNB4,PTPN6,WFS1,HSPA2,UBASH3B,GNAO1,EHD3 |
| 2.932e-02 | -3.53 | neuron part | cellular component | GO:0097458 | 1528 | 33 | 18223 | 280 |
NECAB2,SCAMP1,BACE1,C4A,BLVRB,KIF5C,NDRG2,ABAT,KIF21B,PFN2,TIAM2,NCS1,RGS17,TRIM3,DAB2IP,BNIP3,EPHB6,RAB27B,STXBP1,BDNF,LZTS3,SLC40A1,MPP1,NLGN4X,PPFIA4,PALLD,OR11H4,GNAO1,WFS1,PLK2,TMOD2,APBA2,COBL |
| 2.945e-02 | -3.53 | KRAS.600.LUNG.BREAST_UP.V1_UP | MSigDB lists | KRAS.600.LUNG.BREAST_UP.V1_UP | 265 | 9 | 17377 | 282 |
WDR25,KIF5C,TNFSF15,TTC22,PRDM1,DYNC1I1,FBXO4,DDIT3,OGDHL |
| 2.955e-02 | -3.52 | BOYLAN_MULTIPLE_MYELOMA_PCA3_UP | MSigDB lists | BOYLAN_MULTIPLE_MYELOMA_PCA3_UP | 72 | 4 | 17377 | 282 |
CCDC126,ZNF827,TLN2,PLK2 |
| 2.957e-02 | -3.52 | GO_RIBONUCLEOTIDE_BINDING | MSigDB lists | GO_RIBONUCLEOTIDE_BINDING | 1768 | 39 | 17377 | 282 |
ACVR1,ACSL1,RUNX2,BVES,ARL2,RASL11B,KIF5C,PRKCA,KIF21B,RPS6KL1,EHD3,RASD2,PRKCD,GTF2F2,ACTA2,SGK1,MYH15,EPHB6,PDE4D,RAB27B,DNAH5,HSPA2,PDK1,ADCY1,NUAK2,STRADB,ABCC2,RAB38,ACVR2B,SGK2,DYRK1B,TRIB3,FGR,MAP2K6,GNAO1,PLK2,ERN1,HK2,MAPK13 |
| 2.959e-02 | -3.52 | Kelch-typ_b-propeller | interpro domains | IPR015915 | 73 | 4 | 18492 | 296 |
KLHL31,KLHL3,KLHL23,GAN |
| 2.962e-02 | -3.52 | MECP2 and Associated Rett Syndrome | WikiPathways | WP3584 | 62 | 4 | 5312 | 101 |
SGK1,BDNF,DLX6,MPP1 |
| 2.967e-02 | -3.52 | GABA shunt | BIOCYC pathways | HUMAN_GLUDEG-I-PWY | 3 | 1 | 902 | 9 |
ABAT |
| 2.967e-02 | -3.52 | icosapentaenoate biosynthesis III (8-desaturase, mammals) | BIOCYC pathways | META_PWY-7724 | 3 | 1 | 902 | 9 |
ACSL1 |
| 2.967e-02 | -3.52 | gamma-linolenate biosynthesis II (animals) | BIOCYC pathways | META_PWY-6000 | 3 | 1 | 902 | 9 |
ACSL1 |
| 2.967e-02 | -3.52 | icosapentaenoate biosynthesis II (6-desaturase, mammals) | BIOCYC pathways | META_PWY-7049 | 3 | 1 | 902 | 9 |
ACSL1 |
| 2.973e-02 | -3.52 | SATO_SILENCED_BY_METHYLATION_IN_PANCREATIC_CANCER_1 | MSigDB lists | SATO_SILENCED_BY_METHYLATION_IN_PANCREATIC_CANCER_1 | 398 | 12 | 17377 | 282 |
RGS17,MSX1,PDK1,PMAIP1,ST14,CYB5R2,BNIP3,RAB38,KIF21B,HSPA2,BARX1,PHC1 |
| 2.977e-02 | -3.51 | ELAVL1 (ELAV like RNA binding protein 1) | protein interactions | 1994 | 1780 | 40 | 17029 | 283 |
SCAMP1,ZNF395,ARHGEF11,FBXO4,UBASH3B,LSM11,CEBPA,PRKCA,TENT5C,NCS1,NEO1,FKBP9,PMAIP1,MYC,MARVELD2,PRKCD,SRGAP1,ZNF521,SGK1,VGLL4,DZANK1,BDNF,B3GLCT,PNRC1,KLHL3,NUAK2,STRADB,SATB2,PRDM1,PLEKHA1,SAV1,CTIF,RERE,IGIP,HK2,P4HA1,THAP10,IQSEC2,RNF122,PHC1 |
| 2.987e-02 | -3.51 | G3PDHDRGNASE | prints domains | PR00078 | 2 | 1 | 4652 | 70 |
GAPDH |
| 2.987e-02 | -3.51 | LCACHANNELB3 | prints domains | PR01696 | 2 | 1 | 4652 | 70 |
CACNB4 |
| 2.987e-02 | -3.51 | PROFILIN | prints domains | PR00392 | 2 | 1 | 4652 | 70 |
PFN2 |
| 2.987e-02 | -3.51 | BACEFAMILY | prints domains | PR01815 | 2 | 1 | 4652 | 70 |
BACE1 |
| 2.987e-02 | -3.51 | HISTAMINEH3R | prints domains | PR01471 | 2 | 1 | 4652 | 70 |
ZNF219 |
| 2.987e-02 | -3.51 | DBMONOXGNASE | prints domains | PR00767 | 2 | 1 | 4652 | 70 |
MOXD1 |
| 2.989e-02 | -3.51 | nucleobase-containing small molecule biosynthetic process | biological process | GO:0034404 | 149 | 6 | 17256 | 270 |
PDE4D,GAPDH,SMPDL3A,ALDOA,OGDHL,HK2 |
| 2.989e-02 | -3.51 | muscle cell development | biological process | GO:0055001 | 149 | 6 | 17256 | 270 |
MYOM2,TMOD2,BVES,SMYD3,MYORG,FHOD3 |
| 2.991e-02 | -3.51 | phosphotransferase activity, alcohol group as acceptor | molecular function | GO:0016773 | 785 | 20 | 17224 | 278 |
ACVR1,PDK1,NUAK2,EFNA3,STRADB,ACVR2B,PRKCA,SGK2,GRK3,DYRK1B,FGR,PLK2,RPS6KL1,MAP2K6,ERN1,PRKCD,HK2,SGK1,MAPK13,EPHB6 |
| 2.996e-02 | -3.51 | GABA synthesis, release, reuptake and degradation | REACTOME pathways | R-HSA-888590 | 19 | 2 | 10287 | 148 |
ABAT,STXBP1 |
| 2.996e-02 | -3.51 | TSP1 | smart domains | SM00209 | 65 | 4 | 9493 | 172 |
WISP3,ADAMTS3,HMCN1,ISM1 |
| 3.000e-02 | -3.51 | actin cytoskeleton organization | biological process | GO:0030036 | 461 | 13 | 17256 | 270 |
ARHGAP26,EPB41L5,ARHGEF11,DSTN,ALDOA,NUAK2,TMOD2,MYOM2,PALLD,IQSEC2,PFN2,COBL,FHOD3 |
| 3.004e-02 | -3.51 | GSE43863_NAIVE_VS_MEMORY_LY6C_INT_CXCR5POS_CD4_TCELL_D150_LCMV_UP | MSigDB lists | GSE43863_NAIVE_VS_MEMORY_LY6C_INT_CXCR5POS_CD4_TCELL_D150_LCMV_UP | 183 | 7 | 17377 | 282 |
NDRG2,WNT11,MXI1,ZNF395,RALGPS2,PNRC1,BNIP3L |
| 3.004e-02 | -3.51 | GSE19941_UNSTIM_VS_LPS_AND_IL10_STIM_IL10_KO_MACROPHAGE_UP | MSigDB lists | GSE19941_UNSTIM_VS_LPS_AND_IL10_STIM_IL10_KO_MACROPHAGE_UP | 183 | 7 | 17377 | 282 |
MN1,DZANK1,LONRF1,SHISA2,ABAT,SATB1,ERN1 |
| 3.004e-02 | -3.51 | RPS14_DN.V1_UP | MSigDB lists | RPS14_DN.V1_UP | 183 | 7 | 17377 | 282 |
ACTA2,TNFRSF10C,PDE4D,RASAL2,CACNB4,KMO,PLK2 |
| 3.004e-02 | -3.51 | GSE18893_CTRL_VS_TNF_TREATED_TREG_2H_UP | MSigDB lists | GSE18893_CTRL_VS_TNF_TREATED_TREG_2H_UP | 183 | 7 | 17377 | 282 |
TRIM3,P4HA1,SLC36A4,EXOC6B,SMPDL3A,ERN1,SPATA13 |
| 3.004e-02 | -3.51 | GSE7460_TCONV_VS_TREG_LN_UP | MSigDB lists | GSE7460_TCONV_VS_TREG_LN_UP | 183 | 7 | 17377 | 282 |
MAP7,PDK1,RAB27B,SLC30A4,SATB1,ZHX3,EHD3 |
| 3.004e-02 | -3.51 | GSE1460_INTRATHYMIC_T_PROGENITOR_VS_NAIVE_CD4_TCELL_CORD_BLOOD_DN | MSigDB lists | GSE1460_INTRATHYMIC_T_PROGENITOR_VS_NAIVE_CD4_TCELL_CORD_BLOOD_DN | 183 | 7 | 17377 | 282 |
WWC1,BNIP3,MAPK13,ZNF516,PLEKHA1,BARX1,PLEKHB1 |
| 3.004e-02 | -3.51 | GSE3982_EOSINOPHIL_VS_NEUTROPHIL_DN | MSigDB lists | GSE3982_EOSINOPHIL_VS_NEUTROPHIL_DN | 183 | 7 | 17377 | 282 |
PPM1E,TNFRSF10C,ACSL1,KIAA0355,MAP2K6,HEBP1,PRKCD |
| 3.004e-02 | -3.51 | MEK_UP.V1_UP | MSigDB lists | MEK_UP.V1_UP | 183 | 7 | 17377 | 282 |
CLMN,WNT11,ACSL1,NT5DC2,CAPN5,PKIA,TBC1D8 |
| 3.004e-02 | -3.51 | GSE32423_CTRL_VS_IL7_MEMORY_CD8_TCELL_DN | MSigDB lists | GSE32423_CTRL_VS_IL7_MEMORY_CD8_TCELL_DN | 183 | 7 | 17377 | 282 |
WDR25,B9D1,SATB2,ABCC2,LHPP,PRKCA,ERN1 |
| 3.004e-02 | -3.51 | GSE40274_FOXP3_VS_FOXP3_AND_IRF4_TRANSDUCED_ACTIVATED_CD4_TCELL_DN | MSigDB lists | GSE40274_FOXP3_VS_FOXP3_AND_IRF4_TRANSDUCED_ACTIVATED_CD4_TCELL_DN | 183 | 7 | 17377 | 282 |
CCDC126,PRDM1,ARRDC4,GPR155,RBPMS2,SMPDL3A,GPLD1 |
| 3.006e-02 | -3.50 | voltage-gated calcium channel activity | molecular function | GO:0005245 | 42 | 3 | 17224 | 278 |
GAS6,CACNB4,NCS1 |
| 3.010e-02 | -3.50 | chloride channel regulator activity | molecular function | GO:0017081 | 17 | 2 | 17224 | 278 |
SGK1,SGK2 |
| 3.010e-02 | -3.50 | transmembrane receptor protein serine/threonine kinase activity | molecular function | GO:0004675 | 17 | 2 | 17224 | 278 |
ACVR2B,ACVR1 |
| 3.010e-02 | -3.50 | structural molecule activity conferring elasticity | molecular function | GO:0097493 | 17 | 2 | 17224 | 278 |
MYOM2,EMILIN2 |
| 3.010e-02 | -3.50 | muscle alpha-actinin binding | molecular function | GO:0051371 | 17 | 2 | 17224 | 278 |
MYOM2,PALLD |
| 3.010e-02 | -3.50 | transmembrane-ephrin receptor activity | molecular function | GO:0005005 | 17 | 2 | 17224 | 278 |
EPHB6,EFNA3 |
| 3.017e-02 | -3.50 | V$SOX9_B1 | MSigDB lists | V$SOX9_B1 | 224 | 8 | 17377 | 282 |
PNRC1,GNAO1,EPHB6,PFN2,FANK1,PHC1,NEO1,RERE |
| 3.018e-02 | -3.50 | GSE17974_IL4_AND_ANTI_IL12_VS_UNTREATED_0.5H_ACT_CD4_TCELL_DN | MSigDB lists | GSE17974_IL4_AND_ANTI_IL12_VS_UNTREATED_0.5H_ACT_CD4_TCELL_DN | 144 | 6 | 17377 | 282 |
FAM198B,GAS6,BARX1,FAM131C,ZNF521,ZNF391 |
| 3.030e-02 | -3.50 | GO_RESPONSE_TO_HYDROGEN_PEROXIDE | MSigDB lists | GO_RESPONSE_TO_HYDROGEN_PEROXIDE | 107 | 5 | 17377 | 282 |
BNIP3,PLEKHA1,GNAO1,PRKCD,DDIT3 |
| 3.040e-02 | -3.49 | GO_ACTIVATION_OF_NF_KAPPAB_INDUCING_KINASE_ACTIVITY | MSigDB lists | GO_ACTIVATION_OF_NF_KAPPAB_INDUCING_KINASE_ACTIVITY | 17 | 2 | 17377 | 282 |
TNFSF15,TLR6 |
| 3.040e-02 | -3.49 | GO_PHARYNGEAL_SYSTEM_DEVELOPMENT | MSigDB lists | GO_PHARYNGEAL_SYSTEM_DEVELOPMENT | 17 | 2 | 17377 | 282 |
ACVR1,PLXNA2 |
| 3.040e-02 | -3.49 | GO_SIGNAL_TRANSDUCTION_INVOLVED_IN_REGULATION_OF_GENE_EXPRESSION | MSigDB lists | GO_SIGNAL_TRANSDUCTION_INVOLVED_IN_REGULATION_OF_GENE_EXPRESSION | 17 | 2 | 17377 | 282 |
EPCAM,MSX1 |
| 3.040e-02 | -3.49 | GO_NOTOCHORD_DEVELOPMENT | MSigDB lists | GO_NOTOCHORD_DEVELOPMENT | 17 | 2 | 17377 | 282 |
WNT11,COBL |
| 3.040e-02 | -3.49 | GO_POSITIVE_REGULATION_OF_SIGNAL_TRANSDUCTION_BY_P53_CLASS_MEDIATOR | MSigDB lists | GO_POSITIVE_REGULATION_OF_SIGNAL_TRANSDUCTION_BY_P53_CLASS_MEDIATOR | 17 | 2 | 17377 | 282 |
MSX1,PMAIP1 |
| 3.040e-02 | -3.49 | GO_NEGATIVE_REGULATION_OF_TRANSCRIPTION_REGULATORY_REGION_DNA_BINDING | MSigDB lists | GO_NEGATIVE_REGULATION_OF_TRANSCRIPTION_REGULATORY_REGION_DNA_BINDING | 17 | 2 | 17377 | 282 |
MSX1,DDIT3 |
| 3.040e-02 | -3.49 | GO_SEGMENT_SPECIFICATION | MSigDB lists | GO_SEGMENT_SPECIFICATION | 17 | 2 | 17377 | 282 |
MAFB,COBL |
| 3.040e-02 | -3.49 | REACTOME_GABA_SYNTHESIS_RELEASE_REUPTAKE_AND_DEGRADATION | MSigDB lists | REACTOME_GABA_SYNTHESIS_RELEASE_REUPTAKE_AND_DEGRADATION | 17 | 2 | 17377 | 282 |
ABAT,STXBP1 |
| 3.040e-02 | -3.49 | GO_POSITIVE_REGULATION_OF_PROTEIN_OLIGOMERIZATION | MSigDB lists | GO_POSITIVE_REGULATION_OF_PROTEIN_OLIGOMERIZATION | 17 | 2 | 17377 | 282 |
PMAIP1,BIK |
| 3.040e-02 | -3.49 | LI_ADIPOGENESIS_BY_ACTIVATED_PPARG | MSigDB lists | LI_ADIPOGENESIS_BY_ACTIVATED_PPARG | 17 | 2 | 17377 | 282 |
CEBPA,ACSL1 |
| 3.040e-02 | -3.49 | GO_REGULATION_OF_LIPOPOLYSACCHARIDE_MEDIATED_SIGNALING_PATHWAY | MSigDB lists | GO_REGULATION_OF_LIPOPOLYSACCHARIDE_MEDIATED_SIGNALING_PATHWAY | 17 | 2 | 17377 | 282 |
PRDM1,PRKCA |
| 3.040e-02 | -3.49 | BIOCARTA_MTA3_PATHWAY | MSigDB lists | BIOCARTA_MTA3_PATHWAY | 17 | 2 | 17377 | 282 |
GAPDH,ALDOA |
| 3.040e-02 | -3.49 | ZHENG_RESPONSE_TO_ARSENITE_DN | MSigDB lists | ZHENG_RESPONSE_TO_ARSENITE_DN | 17 | 2 | 17377 | 282 |
PHLDB2,MYC |
| 3.043e-02 | -3.49 | SNTB2 (syntrophin beta 2) | protein interactions | 6645 | 41 | 3 | 17029 | 283 |
SCN5A,TNS1,SAV1 |
| 3.043e-02 | -3.49 | SNAP25 (synaptosome associated protein 25) | protein interactions | 6616 | 41 | 3 | 17029 | 283 |
SCAMP1,PRKCA,STXBP1 |
| 3.043e-02 | -3.49 | FOXP1 (forkhead box P1) | protein interactions | 27086 | 41 | 3 | 17029 | 283 |
SATB2,SATB1,MYC |
| 3.046e-02 | -3.49 | DGUOK (deoxyguanosine kinase) | protein interactions | 1716 | 71 | 4 | 17029 | 283 |
PXN,STXBP1,HPCAL4,GNAO1 |
| 3.049e-02 | -3.49 | GO_VOLTAGE_GATED_CALCIUM_CHANNEL_ACTIVITY | MSigDB lists | GO_VOLTAGE_GATED_CALCIUM_CHANNEL_ACTIVITY | 42 | 3 | 17377 | 282 |
GAS6,CACNB4,NCS1 |
| 3.049e-02 | -3.49 | PID_THROMBIN_PAR1_PATHWAY | MSigDB lists | PID_THROMBIN_PAR1_PATHWAY | 42 | 3 | 17377 | 282 |
PRKCA,GNAO1,PRKCD |
| 3.049e-02 | -3.49 | GO_REGULATION_OF_RELEASE_OF_CYTOCHROME_C_FROM_MITOCHONDRIA | MSigDB lists | GO_REGULATION_OF_RELEASE_OF_CYTOCHROME_C_FROM_MITOCHONDRIA | 42 | 3 | 17377 | 282 |
BNIP3,PMAIP1,BIK |
| 3.049e-02 | -3.49 | GO_EPITHELIAL_CELL_MORPHOGENESIS | MSigDB lists | GO_EPITHELIAL_CELL_MORPHOGENESIS | 42 | 3 | 17377 | 282 |
EPB41L5,PALLD,ST14 |
| 3.050e-02 | -3.49 | CHOP-ATF4 complex | cellular component | GO:1990617 | 2 | 1 | 18223 | 280 |
DDIT3 |
| 3.050e-02 | -3.49 | CHOP-C/EBP complex | cellular component | GO:0036488 | 2 | 1 | 18223 | 280 |
DDIT3 |
| 3.050e-02 | -3.49 | climbing fiber | cellular component | GO:0044301 | 2 | 1 | 18223 | 280 |
DAB2IP |
| 3.050e-02 | -3.49 | transcription factor TFIIF complex | cellular component | GO:0005674 | 2 | 1 | 18223 | 280 |
GTF2F2 |
| 3.050e-02 | -3.49 | procollagen-proline 4-dioxygenase complex | cellular component | GO:0016222 | 2 | 1 | 18223 | 280 |
P4HA1 |
| 3.050e-02 | -3.49 | CHOP-ATF3 complex | cellular component | GO:1990622 | 2 | 1 | 18223 | 280 |
DDIT3 |
| 3.050e-02 | -3.49 | IRE1-RACK1-PP2A complex | cellular component | GO:1990630 | 2 | 1 | 18223 | 280 |
ERN1 |
| 3.051e-02 | -3.49 | cell junction | cellular component | GO:0030054 | 1256 | 28 | 18223 | 280 |
ARHGAP26,EPB41L5,SCN5A,PHLDB2,LZTS3,PXN,BVES,C4A,PTPN6,CAPN5,ARL2,NLGN4X,NRN1,ABCC2,TNS1,PALLD,JAM3,HMCN1,CBLN1,NCS1,EPCAM,RGS17,LMLN,DACT1,MARVELD2,PRKCD,EHD3,TLN2 |
| 3.056e-02 | -3.49 | haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-plasma_cell_myeloma | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-plasma_cell_myeloma | 1299 | 30 | 17385 | 281 |
EPB41L5,SCN5A,PRSS16,KLHL23,ARHGEF11,PTPN21,SETBP1,WWC1,NRN1,CEBPA,PLEKHA1,PRDM1,DYNC1I1,ZNF558,SPNS1,TMEM53,RALGPS2,GPR155,MYC,RASGRF2,EEPD1,TRIM3,MYOM2,MYH15,ZNF474,TANC2,TLN2,DNAH5,APBA2,TBC1D8 |
| 3.056e-02 | -3.49 | plasma_cell_myeloma | COSMIC cancer mutations | plasma_cell_myeloma | 1299 | 30 | 17385 | 281 |
EPB41L5,SCN5A,PRSS16,KLHL23,ARHGEF11,PTPN21,SETBP1,WWC1,NRN1,CEBPA,PLEKHA1,PRDM1,DYNC1I1,ZNF558,SPNS1,TMEM53,RALGPS2,GPR155,MYC,RASGRF2,EEPD1,TRIM3,MYOM2,MYH15,ZNF474,TANC2,TLN2,DNAH5,APBA2,TBC1D8 |
| 3.060e-02 | -3.49 | Downstream signal transduction | REACTOME pathways | R-HSA-186763 | 352 | 10 | 10287 | 148 |
IL17RD,TRIB3,RASAL2,DUSP8,RASGRF2,PRKCD,ADCY1,DAB2IP,ITPR2,PRKCA |
| 3.075e-02 | -3.48 | adenyl nucleotide binding | molecular function | GO:0030554 | 1514 | 34 | 17224 | 278 |
RUNX2,ACSL1,ACVR1,BVES,KIF5C,KIF21B,PRKCA,RPS6KL1,PRKCD,EHD3,GTF2F2,ACTA2,SGK1,MYH15,PDE4D,EPHB6,DNAH5,HSPA2,PDK1,NUAK2,ADCY1,STRADB,ABCC2,ACVR2B,SGK2,GRK3,DYRK1B,TRIB3,FGR,MAP2K6,PLK2,ERN1,HK2,MAPK13 |
| 3.081e-02 | -3.48 | GSE557_WT_VS_CIITA_KO_DC_DN | MSigDB lists | GSE557_WT_VS_CIITA_KO_DC_DN | 184 | 7 | 17377 | 282 |
MXI1,GAS6,PRSS16,DUSP8,SATB1,HSPA2,SMPDL3A |
| 3.081e-02 | -3.48 | GSE5589_LPS_VS_LPS_AND_IL10_STIM_MACROPHAGE_45MIN_DN | MSigDB lists | GSE5589_LPS_VS_LPS_AND_IL10_STIM_MACROPHAGE_45MIN_DN | 184 | 7 | 17377 | 282 |
MAFB,RUNX2,DNAH5,CFHR1,HEBP1,TIAM2,GPLD1 |
| 3.081e-02 | -3.48 | GSE40274_FOXP3_VS_FOXP3_AND_PBX1_TRANSDUCED_ACTIVATED_CD4_TCELL_UP | MSigDB lists | GSE40274_FOXP3_VS_FOXP3_AND_PBX1_TRANSDUCED_ACTIVATED_CD4_TCELL_UP | 184 | 7 | 17377 | 282 |
CCDC126,PRDM1,UBASH3B,RBPMS2,SMPDL3A,NUAK2,ZDHHC23 |
| 3.081e-02 | -3.48 | GSE8384_CTRL_VS_B_ABORTUS_4H_MAC_CELL_LINE_UP | MSigDB lists | GSE8384_CTRL_VS_B_ABORTUS_4H_MAC_CELL_LINE_UP | 184 | 7 | 17377 | 282 |
ARL2,IFT81,PDK1,TNFRSF17,ATOX1,PTPN21,RERE |
| 3.081e-02 | -3.48 | GSE3994_WT_VS_PAC1_KO_ACTIVATED_MAST_CELL_UP | MSigDB lists | GSE3994_WT_VS_PAC1_KO_ACTIVATED_MAST_CELL_UP | 184 | 7 | 17377 | 282 |
KIF5C,NDRG2,NUMBL,FGR,TNFRSF17,JAM3,CBLN1 |
| 3.081e-02 | -3.48 | GSE18281_PERIMEDULLARY_CORTICAL_REGION_VS_WHOLE_MEDULLA_THYMUS_UP | MSigDB lists | GSE18281_PERIMEDULLARY_CORTICAL_REGION_VS_WHOLE_MEDULLA_THYMUS_UP | 184 | 7 | 17377 | 282 |
ARHGAP28,TCF7L1,CEBPA,EPHB6,PLEKHA1,DYNC1I1,CYP2J2 |
| 3.081e-02 | -3.48 | GSE36476_CTRL_VS_TSST_ACT_16H_MEMORY_CD4_TCELL_OLD_UP | MSigDB lists | GSE36476_CTRL_VS_TSST_ACT_16H_MEMORY_CD4_TCELL_OLD_UP | 184 | 7 | 17377 | 282 |
MXI1,PDE4D,PDK1,ZNF395,KLHL3,GNAO1,BNIP3L |
| 3.081e-02 | -3.48 | GSE2770_UNTREATED_VS_TGFB_AND_IL12_TREATED_ACT_CD4_TCELL_2H_UP | MSigDB lists | GSE2770_UNTREATED_VS_TGFB_AND_IL12_TREATED_ACT_CD4_TCELL_2H_UP | 184 | 7 | 17377 | 282 |
WWC1,RGS16,EPHB6,PFN2,RPS6KL1,LSM11,ZNF521 |
| 3.083e-02 | -3.48 | MODULE_1 | MSigDB lists | MODULE_1 | 355 | 11 | 17377 | 282 |
QSOX1,MSX1,PNRC1,CFHR1,MYC,WFS1,WWTR1,SGK1,P4HA1,DBP,MTUS1 |
| 3.084e-02 | -3.48 | PRKACA (protein kinase cAMP-activated catalytic subunit alpha) | protein interactions | 5566 | 261 | 9 | 17029 | 283 |
DYRK1B,C2orf88,ITPR2,PDE4D,KLHL3,DOCK1,DACT1,GPR161,PKIA |
| 3.087e-02 | -3.48 | transcription regulatory region sequence-specific DNA binding | molecular function | GO:0000976 | 738 | 19 | 17224 | 278 |
RUNX2,MSX1,MXI1,ZNF516,ZNF395,ZHX3,SOX21,MAFB,CEBPA,SATB2,PRDM1,ZNF219,SATB1,MYC,DLX2,DBP,SMYD3,BARX1,DDIT3 |
| 3.088e-02 | -3.48 | GO_NEGATIVE_REGULATION_OF_MAP_KINASE_ACTIVITY | MSigDB lists | GO_NEGATIVE_REGULATION_OF_MAP_KINASE_ACTIVITY | 73 | 4 | 17377 | 282 |
DAB2IP,DUSP8,PTPN6,PRKCD |
| 3.088e-02 | -3.48 | CHEBOTAEV_GR_TARGETS_UP | MSigDB lists | CHEBOTAEV_GR_TARGETS_UP | 73 | 4 | 17377 | 282 |
NDRG2,C2orf88,RECK,NT5DC2 |
| 3.088e-02 | -3.48 | GO_POSITIVE_REGULATION_OF_PROTEIN_BINDING | MSigDB lists | GO_POSITIVE_REGULATION_OF_PROTEIN_BINDING | 73 | 4 | 17377 | 282 |
EPB41L5,TRIB3,PLK2,DACT1 |
| 3.088e-02 | -3.48 | GARGALOVIC_RESPONSE_TO_OXIDIZED_PHOSPHOLIPIDS_TURQUOISE_UP | MSigDB lists | GARGALOVIC_RESPONSE_TO_OXIDIZED_PHOSPHOLIPIDS_TURQUOISE_UP | 73 | 4 | 17377 | 282 |
SGK1,ACVR1,ZNF697,MYC |
| 3.088e-02 | -3.48 | GO_PLATELET_ALPHA_GRANULE | MSigDB lists | GO_PLATELET_ALPHA_GRANULE | 73 | 4 | 17377 | 282 |
QSOX1,GAS6,STXBP1,ALDOA |
| 3.088e-02 | -3.48 | GO_VASCULAR_ENDOTHELIAL_GROWTH_FACTOR_RECEPTOR_SIGNALING_PATHWAY | MSigDB lists | GO_VASCULAR_ENDOTHELIAL_GROWTH_FACTOR_RECEPTOR_SIGNALING_PATHWAY | 73 | 4 | 17377 | 282 |
MAPK13,DAB2IP,PXN,DOCK1 |
| 3.088e-02 | -3.48 | GO_REGULATION_OF_ACTIN_FILAMENT_BUNDLE_ASSEMBLY | MSigDB lists | GO_REGULATION_OF_ACTIN_FILAMENT_BUNDLE_ASSEMBLY | 73 | 4 | 17377 | 282 |
PPM1E,PHLDB2,WNT11,PFN2 |
| 3.092e-02 | -3.48 | cell death | biological process | GO:0008219 | 1075 | 25 | 17256 | 270 |
GAPDH,PDK1,ST14,DOCK1,PTPN6,BIK,BNIP3L,NUAK2,GAS6,TNFRSF10C,PRKCA,SAV1,SATB1,TRIB3,PMAIP1,MAP2K6,MYC,PRKCD,ERN1,HK2,SGK1,TNFSF15,DAB2IP,BNIP3,DDIT3 |
| 3.103e-02 | -3.47 | cerebellum | COSMIC cancer mutations | cerebellum | 787 | 20 | 17385 | 281 |
BDNF,RUNX2,ACVR1,LGR4,SETBP1,SLC36A4,SLC2A13,ITPR2,PALLD,HMCN1,FHOD3,MTUS1,ANKRD31,KMO,GNAO1,SRGAP1,DAB2IP,PDE4D,COBL,KIAA1549 |
| 3.105e-02 | -3.47 | GO_REGULATION_OF_METAL_ION_TRANSPORT | MSigDB lists | GO_REGULATION_OF_METAL_ION_TRANSPORT | 311 | 10 | 17377 | 282 |
SCN5A,UBASH3B,GNAO1,PTPN6,WFS1,SGK1,PDE4D,SGK2,CACNB4,HSPA2 |
| 3.105e-02 | -3.47 | detoxification of mercury ion | biological process | GO:0050787 | 2 | 1 | 17256 | 270 |
ABCC2 |
| 3.105e-02 | -3.47 | positive regulation of high-density lipoprotein particle clearance | biological process | GO:0010983 | 2 | 1 | 17256 | 270 |
GPLD1 |
| 3.105e-02 | -3.47 | cellular response to vitamin K | biological process | GO:0071307 | 2 | 1 | 17256 | 270 |
GAS6 |
| 3.105e-02 | -3.47 | histone H4-K20 demethylation | biological process | GO:0035574 | 2 | 1 | 17256 | 270 |
KDM7A |
| 3.105e-02 | -3.47 | abducens nerve morphogenesis | biological process | GO:0021598 | 2 | 1 | 17256 | 270 |
MAFB |
| 3.105e-02 | -3.47 | negative regulation of protein import into nucleus, translocation | biological process | GO:0033159 | 2 | 1 | 17256 | 270 |
GAS6 |
| 3.105e-02 | -3.47 | abducens nerve development | biological process | GO:0021560 | 2 | 1 | 17256 | 270 |
MAFB |
| 3.105e-02 | -3.47 | cell-cell signaling involved in metanephros development | biological process | GO:0072204 | 2 | 1 | 17256 | 270 |
LGR4 |
| 3.105e-02 | -3.47 | neuroblast division in subventricular zone | biological process | GO:0021849 | 2 | 1 | 17256 | 270 |
NUMBL |
| 3.105e-02 | -3.47 | negative regulation of ATF6-mediated unfolded protein response | biological process | GO:1903892 | 2 | 1 | 17256 | 270 |
WFS1 |
| 3.105e-02 | -3.47 | positive regulation of retina development in camera-type eye | biological process | GO:1902868 | 2 | 1 | 17256 | 270 |
DLX2 |
| 3.105e-02 | -3.47 | cell-cell signaling involved in kidney development | biological process | GO:0060995 | 2 | 1 | 17256 | 270 |
LGR4 |
| 3.105e-02 | -3.47 | fatty acid omega-oxidation | biological process | GO:0010430 | 2 | 1 | 17256 | 270 |
CYP4V2 |
| 3.105e-02 | -3.47 | rhombomere 5 development | biological process | GO:0021571 | 2 | 1 | 17256 | 270 |
MAFB |
| 3.105e-02 | -3.47 | detection of diacyl bacterial lipopeptide | biological process | GO:0042496 | 2 | 1 | 17256 | 270 |
TLR6 |
| 3.105e-02 | -3.47 | vascular endothelial growth factor receptor-2 signaling pathway | biological process | GO:0036324 | 2 | 1 | 17256 | 270 |
DAB2IP |
| 3.105e-02 | -3.47 | cerebellar granule cell precursor tangential migration | biological process | GO:0021935 | 2 | 1 | 17256 | 270 |
PLXNA2 |
| 3.105e-02 | -3.47 | unidimensional cell growth | biological process | GO:0009826 | 2 | 1 | 17256 | 270 |
EPB41L5 |
| 3.105e-02 | -3.47 | divalent metal ion export | biological process | GO:0070839 | 2 | 1 | 17256 | 270 |
SLC40A1 |
| 3.105e-02 | -3.47 | positive regulation of transforming growth factor beta2 production | biological process | GO:0032915 | 2 | 1 | 17256 | 270 |
WNT11 |
| 3.105e-02 | -3.47 | endocardial cushion cell differentiation | biological process | GO:0061443 | 2 | 1 | 17256 | 270 |
ACVR1 |
| 3.105e-02 | -3.47 | regulation of endocannabinoid signaling pathway | biological process | GO:2000124 | 2 | 1 | 17256 | 270 |
ABHD6 |
| 3.105e-02 | -3.47 | retrograde trans-synaptic signaling by neuropeptide | biological process | GO:0099082 | 2 | 1 | 17256 | 270 |
BDNF |
| 3.105e-02 | -3.47 | positive regulation of neural retina development | biological process | GO:0061075 | 2 | 1 | 17256 | 270 |
DLX2 |
| 3.105e-02 | -3.47 | positive regulation of determination of dorsal identity | biological process | GO:2000017 | 2 | 1 | 17256 | 270 |
ACVR1 |
| 3.105e-02 | -3.47 | regulation of renal albumin absorption | biological process | GO:2000532 | 2 | 1 | 17256 | 270 |
GAS6 |
| 3.105e-02 | -3.47 | synaptonemal complex disassembly | biological process | GO:0070194 | 2 | 1 | 17256 | 270 |
HSPA2 |
| 3.105e-02 | -3.47 | canonical Wnt signaling pathway involved in metanephric kidney development | biological process | GO:0061290 | 2 | 1 | 17256 | 270 |
LGR4 |
| 3.105e-02 | -3.47 | planar cell polarity pathway involved in gastrula mediolateral intercalation | biological process | GO:0060775 | 2 | 1 | 17256 | 270 |
WNT11 |
| 3.105e-02 | -3.47 | histone H3-T6 phosphorylation | biological process | GO:0035408 | 2 | 1 | 17256 | 270 |
PRKCA |
| 3.105e-02 | -3.47 | cerebellar Purkinje cell layer maturation | biological process | GO:0021691 | 2 | 1 | 17256 | 270 |
RERE |
| 3.105e-02 | -3.47 | negative regulation of relaxation of cardiac muscle | biological process | GO:1901898 | 2 | 1 | 17256 | 270 |
PDE4D |
| 3.105e-02 | -3.47 | regulation of extrathymic T cell differentiation | biological process | GO:0033082 | 2 | 1 | 17256 | 270 |
PRDM1 |
| 3.105e-02 | -3.47 | gamma-aminobutyric acid catabolic process | biological process | GO:0009450 | 2 | 1 | 17256 | 270 |
ABAT |
| 3.105e-02 | -3.47 | regulation of transcription involved in anterior/posterior axis specification | biological process | GO:0044324 | 2 | 1 | 17256 | 270 |
DDIT3 |
| 3.105e-02 | -3.47 | positive regulation of mesenchymal cell apoptotic process | biological process | GO:2001055 | 2 | 1 | 17256 | 270 |
MSX1 |
| 3.105e-02 | -3.47 | abducens nerve formation | biological process | GO:0021599 | 2 | 1 | 17256 | 270 |
MAFB |
| 3.105e-02 | -3.47 | peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase | biological process | GO:0017186 | 2 | 1 | 17256 | 270 |
QPCTL |
| 3.105e-02 | -3.47 | response to thyrotropin-releasing hormone | biological process | GO:1905225 | 2 | 1 | 17256 | 270 |
TSHR |
| 3.105e-02 | -3.47 | positive regulation of dense core granule biogenesis | biological process | GO:2000707 | 2 | 1 | 17256 | 270 |
PRKCA |
| 3.105e-02 | -3.47 | abortive mitotic cell cycle | biological process | GO:0033277 | 2 | 1 | 17256 | 270 |
PTPN6 |
| 3.105e-02 | -3.47 | iron import into the mitochondrion | biological process | GO:0048250 | 2 | 1 | 17256 | 270 |
SLC25A28 |
| 3.105e-02 | -3.47 | uroporphyrinogen III metabolic process | biological process | GO:0046502 | 2 | 1 | 17256 | 270 |
UROS |
| 3.105e-02 | -3.47 | cerebral cortex GABAergic interneuron fate commitment | biological process | GO:0021893 | 2 | 1 | 17256 | 270 |
DLX2 |
| 3.105e-02 | -3.47 | retrograde trans-synaptic signaling by neuropeptide, modulating synaptic transmission | biological process | GO:0099083 | 2 | 1 | 17256 | 270 |
BDNF |
| 3.105e-02 | -3.47 | peptidyl-cysteine S-trans-nitrosylation | biological process | GO:0035606 | 2 | 1 | 17256 | 270 |
GAPDH |
| 3.105e-02 | -3.47 | uroporphyrinogen III biosynthetic process | biological process | GO:0006780 | 2 | 1 | 17256 | 270 |
UROS |
| 3.105e-02 | -3.47 | response to anisomycin | biological process | GO:0072739 | 2 | 1 | 17256 | 270 |
MAPK13 |
| 3.105e-02 | -3.47 | sinoatrial node cell development | biological process | GO:0060931 | 2 | 1 | 17256 | 270 |
BVES |
| 3.105e-02 | -3.47 | thyroid-stimulating hormone signaling pathway | biological process | GO:0038194 | 2 | 1 | 17256 | 270 |
TSHR |
| 3.105e-02 | -3.47 | negative regulation of determination of dorsal identity | biological process | GO:2000016 | 2 | 1 | 17256 | 270 |
DDIT3 |
| 3.105e-02 | -3.47 | regulation of brain-derived neurotrophic factor receptor signaling pathway | biological process | GO:0031548 | 2 | 1 | 17256 | 270 |
BDNF |
| 3.105e-02 | -3.47 | positive regulation of amacrine cell differentiation | biological process | GO:1902871 | 2 | 1 | 17256 | 270 |
DLX2 |
| 3.105e-02 | -3.47 | Wnt signaling pathway involved in kidney development | biological process | GO:0061289 | 2 | 1 | 17256 | 270 |
LGR4 |
| 3.105e-02 | -3.47 | cellular response to amine stimulus | biological process | GO:0071418 | 2 | 1 | 17256 | 270 |
UROS |
| 3.105e-02 | -3.47 | negative regulation of G-protein coupled receptor internalization | biological process | GO:1904021 | 2 | 1 | 17256 | 270 |
NECAB2 |
| 3.105e-02 | -3.47 | mediolateral intercalation | biological process | GO:0060031 | 2 | 1 | 17256 | 270 |
WNT11 |
| 3.105e-02 | -3.47 | collateral sprouting in absence of injury | biological process | GO:0048669 | 2 | 1 | 17256 | 270 |
COBL |
| 3.105e-02 | -3.47 | regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment | biological process | GO:0021882 | 2 | 1 | 17256 | 270 |
DLX2 |
| 3.105e-02 | -3.47 | positive regulation of phospholipid catabolic process | biological process | GO:0060697 | 2 | 1 | 17256 | 270 |
PRKCD |
| 3.105e-02 | -3.47 | macrophage cytokine production | biological process | GO:0010934 | 2 | 1 | 17256 | 270 |
GAS6 |
| 3.105e-02 | -3.47 | regulation of transcription from RNA polymerase II promoter in response to iron | biological process | GO:0034395 | 2 | 1 | 17256 | 270 |
SLC40A1 |
| 3.105e-02 | -3.47 | regulation of vesicle docking | biological process | GO:0106020 | 2 | 1 | 17256 | 270 |
STXBP1 |
| 3.107e-02 | -3.47 | GSE36891_POLYIC_TLR3_VS_PAM_TLR2_STIM_PERITONEAL_MACROPHAGE_UP | MSigDB lists | GSE36891_POLYIC_TLR3_VS_PAM_TLR2_STIM_PERITONEAL_MACROPHAGE_UP | 145 | 6 | 17377 | 282 |
SGK1,PRDM1,PMAIP1,PLK2,ZIC5,PLEKHB1 |
| 3.107e-02 | -3.47 | TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_8D_UP | MSigDB lists | TAKEDA_TARGETS_OF_NUP98_HOXA9_FUSION_8D_UP | 145 | 6 | 17377 | 282 |
MAP7,BDNF,SLC40A1,RAB27B,HERC6,PALLD |
| 3.107e-02 | -3.47 | regulation of MAPK cascade | biological process | GO:0043408 | 762 | 19 | 17256 | 270 |
NECAB2,DUSP8,PTPN6,NDRG2,WWC1,GAREM1,GAS6,TNFRSF10C,PRKCA,TLR6,TRIB3,DACT1,MAP2K6,MYC,PRKCD,ERN1,INAVA,DAB2IP,EPHB6 |
| 3.111e-02 | -3.47 | PDZ | interpro domains | IPR001478 | 147 | 6 | 18492 | 296 |
RHPN2,ARHGEF11,RADIL,APBA2,MPP1,TIAM2 |
| 3.115e-02 | -3.47 | human chr3q13.31 | chromosome location | human chr3q13.31 | 22 | 2 | 26185 | 331 |
CCDC191,ZDHHC23 |
| 3.115e-02 | -3.47 | human chr20p12.1 | chromosome location | human chr20p12.1 | 22 | 2 | 26185 | 331 |
ISM1,DSTN |
| 3.118e-02 | -3.47 | mTOR signaling pathway | Pathway Interaction DB | mtor_4pathway | 60 | 4 | 2226 | 45 |
SGK1,BNIP3,PXN,PRKCA |
| 3.128e-02 | -3.46 | regulation of biomineral tissue development | biological process | GO:0070167 | 76 | 4 | 17256 | 270 |
ENAM,GAS6,ACVR2B,ACVR1 |
| 3.132e-02 | -3.46 | purine ribonucleotide binding | molecular function | GO:0032555 | 1840 | 40 | 17224 | 278 |
RUNX2,ACSL1,ACVR1,BVES,ARL2,KIF5C,RASL11B,KIF21B,PRKCA,RPS6KL1,PRKCD,RASD2,EHD3,GTF2F2,ACTA2,SGK1,MYH15,PDE4D,EPHB6,RAB27B,DNAH5,HSPA2,PDK1,NUAK2,ADCY1,STRADB,ABCC2,RAB38,ACVR2B,SGK2,GRK3,DYRK1B,TRIB3,FGR,PLK2,MAP2K6,GNAO1,ERN1,HK2,MAPK13 |
| 3.134e-02 | -3.46 | Corticotropin-releasing hormone signaling pathway | WikiPathways | WP2355 | 93 | 5 | 5312 | 101 |
PRKCA,GRK3,GNAO1,PRKCD,ERN1 |
| 3.137e-02 | -3.46 | DIAZ_CHRONIC_MEYLOGENOUS_LEUKEMIA_DN | MSigDB lists | DIAZ_CHRONIC_MEYLOGENOUS_LEUKEMIA_DN | 108 | 5 | 17377 | 282 |
MN1,MAFB,GAPDH,SATB1,DACT1 |
| 3.137e-02 | -3.46 | GO_REGULATION_OF_OSTEOBLAST_DIFFERENTIATION | MSigDB lists | GO_REGULATION_OF_OSTEOBLAST_DIFFERENTIATION | 108 | 5 | 17377 | 282 |
CEBPA,ACVR2B,ACVR1,RUNX2,ZHX3 |
| 3.137e-02 | -3.46 | GSE37605_C57BL6_VS_NOD_FOXP3_IRES_GFP_TREG_UP | MSigDB lists | GSE37605_C57BL6_VS_NOD_FOXP3_IRES_GFP_TREG_UP | 108 | 5 | 17377 | 282 |
SETBP1,MAPK13,MYH15,ABCC2,EPHB6 |
| 3.138e-02 | -3.46 | regulation of interleukin-6 production | biological process | GO:0032675 | 112 | 5 | 17256 | 270 |
IL17D,INAVA,MAPK13,GAS6,TLR6 |
| 3.138e-02 | -3.46 | striated muscle contraction | biological process | GO:0006941 | 112 | 5 | 17256 | 270 |
SCN5A,MYOM2,ARHGEF11,MAP2K6,ALDOA |
| 3.138e-02 | -3.46 | protein binding | molecular function | GO:0005515 | 11470 | 200 | 17224 | 278 |
ARHGAP26,ACVR1,LGR4,RECK,LSM11,PTPN21,NDRG2,CEBPA,ITPR2,ABAT,PRKCA,CACNB4,TENT5C,NCS1,EPCAM,CPNE2,PPM1E,PMAIP1,MARVELD2,CFHR1,EPHB6,TLN2,TSHR,FANK1,TBC1D8,SMIM20,PNRC1,KLHL23,KLHL3,WISP3,EXOC6B,DSTN,ATOX1,BNIP3L,ABCC2,TNS1,ACVR2B,PLEKHA1,SAV1,PLEKHB1,SPNS1,DYRK1B,TCF7L1,PLK2,RASGRF2,ERN1,ALDOA,MAPK13,TMOD2,DLX2,APBA2,LONRF1,SCN5A,RGS16,RUNX2,ZHX3,BVES,FBXO4,UBASH3B,ATP6V1E2,SETBP1,RASL11B,TNFRSF10C,SATB1,DYNC1I1,PFN2,HPCAL4,FHOD3,MTUS1,IL17D,NUMBL,SLC30A4,RALGPS2,MYC,SRGAP1,EBF4,GAN,INAVA,BNIP3,MOXD1,VGLL4,STXBP1,EPB41L5,ENAM,BDNF,EFNA3,SPATA13,PPFIA4,WDR25,WWC1,MAFB,STRADB,PRDM1,LHPP,ARRDC4,ADAMTS3,LRRIQ3,EMILIN2,HK2,CLMN,IQSEC2,SMYD3,ZNF516,SCAMP1,RASAL2,DOCK1,C4A,FAM131C,CCDC110,PLXNA2,KIF21B,COLEC10,RADIL,CBLN1,TIAM2,ZNF827,KCTD15,DACT1,ZNF521,MAP7,DAB2IP,MYH15,PDE4D,PJA1,RAB27B,DNAH5,TMEM120B,HSPA2,DZANK1,PHLDB2,GAPDH,PDK1,CYB5R2,PTPN6,ADCY1,NLGN4X,WNT11,SATB2,PXYLP1,RAB38,TBC1D16,JAM3,IFT81,RBPMS2,WFS1,WWTR1,PLEKHG1,P4HA1,TNFSF15,DISP1,COBL,KCTD1,C2orf88,CCDC148,NECAB2,MXI1,ARHGEF11,BACE1,BIK,ARL2,KIF5C,SLX1B,GAS6,ZNF219,NEO1,KDM7A,RGS17,PRKCD,EHD3,RASD2,GTF2F2,ACTA2,SGK1,TRIM3,KIAA0408,SMPDL3A,PARP9,B9D1,SLC40A1,PXN,MSX1,MPP1,CCDC184,NUAK2,OGDHL,GAREM1,PALLD,TLR6,CTIF,RERE,TRIB3,FGR,GNAO1,MAP2K6,MYOM2,THAP10,B4GALT7,DDIT3,PKIA,PHC1 |
| 3.153e-02 | -3.46 | 2-oxogl_dehyd_N | pfam domains | PF16078 | 2 | 1 | 17054 | 271 |
OGDHL |
| 3.153e-02 | -3.46 | NAD_binding_10 | pfam domains | PF13460 | 2 | 1 | 17054 | 271 |
BLVRB |
| 3.153e-02 | -3.46 | Cobl | pfam domains | PF09469 | 2 | 1 | 17054 | 271 |
COBL |
| 3.153e-02 | -3.46 | DUF3827 | pfam domains | PF12877 | 2 | 1 | 17054 | 271 |
KIAA1549 |
| 3.153e-02 | -3.46 | SOUL | pfam domains | PF04832 | 2 | 1 | 17054 | 271 |
HEBP1 |
| 3.153e-02 | -3.46 | Gp_dh_N | pfam domains | PF00044 | 2 | 1 | 17054 | 271 |
GAPDH |
| 3.153e-02 | -3.46 | VBS | pfam domains | PF08913 | 2 | 1 | 17054 | 271 |
TLN2 |
| 3.153e-02 | -3.46 | CATSPERD | pfam domains | PF15020 | 2 | 1 | 17054 | 271 |
CATSPERE |
| 3.153e-02 | -3.46 | vATP-synt_E | pfam domains | PF01991 | 2 | 1 | 17054 | 271 |
ATP6V1E2 |
| 3.153e-02 | -3.46 | Neogenin_C | pfam domains | PF06583 | 2 | 1 | 17054 | 271 |
NEO1 |
| 3.153e-02 | -3.46 | Dynein_IC2 | pfam domains | PF11540 | 2 | 1 | 17054 | 271 |
DYNC1I1 |
| 3.153e-02 | -3.46 | NumbF | pfam domains | PF06311 | 2 | 1 | 17054 | 271 |
NUMBL |
| 3.153e-02 | -3.46 | Sec15 | pfam domains | PF04091 | 2 | 1 | 17054 | 271 |
EXOC6B |
| 3.153e-02 | -3.46 | Talin_middle | pfam domains | PF09141 | 2 | 1 | 17054 | 271 |
TLN2 |
| 3.153e-02 | -3.46 | Gp_dh_C | pfam domains | PF02800 | 2 | 1 | 17054 | 271 |
GAPDH |
| 3.153e-02 | -3.46 | Atrophin-1 | pfam domains | PF03154 | 2 | 1 | 17054 | 271 |
RERE |
| 3.153e-02 | -3.46 | TMPIT | pfam domains | PF07851 | 2 | 1 | 17054 | 271 |
TMEM120B |
| 3.153e-02 | -3.46 | ATP-synt_S1 | pfam domains | PF05827 | 2 | 1 | 17054 | 271 |
ATP6AP1L |
| 3.153e-02 | -3.46 | DUF4525 | pfam domains | PF15027 | 2 | 1 | 17054 | 271 |
CCDC126 |
| 3.153e-02 | -3.46 | NRN1 | pfam domains | PF15056 | 2 | 1 | 17054 | 271 |
NRN1 |
| 3.153e-02 | -3.46 | FAM198 | pfam domains | PF15051 | 2 | 1 | 17054 | 271 |
FAM198B |
| 3.157e-02 | -3.46 | GO_POSITIVE_REGULATION_OF_ION_TRANSPORT | MSigDB lists | GO_POSITIVE_REGULATION_OF_ION_TRANSPORT | 226 | 8 | 17377 | 282 |
SCN5A,MAP2K6,WFS1,PRKCD,SGK1,ABAT,SGK2,HSPA2 |
| 3.160e-02 | -3.45 | GSE40273_EOS_KO_VS_WT_TREG_DN | MSigDB lists | GSE40273_EOS_KO_VS_WT_TREG_DN | 185 | 7 | 17377 | 282 |
MAP7,STXBP1,RNF157,ABHD6,MARVELD2,BLVRB,NUAK2 |
| 3.160e-02 | -3.45 | GSE11057_CD4_EFF_MEM_VS_PBMC_DN | MSigDB lists | GSE11057_CD4_EFF_MEM_VS_PBMC_DN | 185 | 7 | 17377 | 282 |
KIAA0513,SETBP1,ACSL1,BLVRB,PRKCD,TBC1D8,BNIP3L |
| 3.160e-02 | -3.45 | GSE21774_CD62L_POS_CD56_BRIGHT_VS_CD62L_NEG_CD56_DIM_NK_CELL_DN | MSigDB lists | GSE21774_CD62L_POS_CD56_BRIGHT_VS_CD62L_NEG_CD56_DIM_NK_CELL_DN | 185 | 7 | 17377 | 282 |
EPB41L5,KIAA0355,IGIP,MARVELD2,RBPMS2,CYP4V2,PHC1 |
| 3.160e-02 | -3.45 | GSE12392_WT_VS_IFNB_KO_CD8A_POS_SPLEEN_DC_DN | MSigDB lists | GSE12392_WT_VS_IFNB_KO_CD8A_POS_SPLEEN_DC_DN | 185 | 7 | 17377 | 282 |
TNS1,TNFRSF17,ST14,ABHD6,KIAA1549,EXOC6B,ATOX1 |
| 3.160e-02 | -3.45 | GO_DEVELOPMENTAL_MATURATION | MSigDB lists | GO_DEVELOPMENTAL_MATURATION | 185 | 7 | 17377 | 282 |
CEBPA,RAB38,RUNX2,STXBP1,RECK,DDIT3,RERE |
| 3.160e-02 | -3.45 | GSE21063_WT_VS_NFATC1_KO_BCELL_UP | MSigDB lists | GSE21063_WT_VS_NFATC1_KO_BCELL_UP | 185 | 7 | 17377 | 282 |
TMC7,TNS1,ARRDC4,EHD3,GPR161,PARP9,EFNA3 |
| 3.160e-02 | -3.45 | GSE41867_NAIVE_VS_DAY6_LCMV_ARMSTRONG_EFFECTOR_CD8_TCELL_UP | MSigDB lists | GSE41867_NAIVE_VS_DAY6_LCMV_ARMSTRONG_EFFECTOR_CD8_TCELL_UP | 185 | 7 | 17377 | 282 |
WWC1,STRADB,SAV1,TANC2,SLC30A4,MPP1,ZNF521 |
| 3.160e-02 | -3.45 | GSE3982_CENT_MEMORY_CD4_TCELL_VS_NKCELL_DN | MSigDB lists | GSE3982_CENT_MEMORY_CD4_TCELL_VS_NKCELL_DN | 185 | 7 | 17377 | 282 |
ARHGAP26,TMEM53,CEBPA,RAB38,KIF21B,PALLD,PTPN6 |
| 3.160e-02 | -3.45 | GSE30083_SP3_VS_SP4_THYMOCYTE_UP | MSigDB lists | GSE30083_SP3_VS_SP4_THYMOCYTE_UP | 185 | 7 | 17377 | 282 |
IFT81,ABCC2,MXI1,ACVR2B,RAB27B,SATB1,TMEM120B |
| 3.160e-02 | -3.45 | GSE24081_CONTROLLER_VS_PROGRESSOR_HIV_SPECIFIC_CD8_TCELL_UP | MSigDB lists | GSE24081_CONTROLLER_VS_PROGRESSOR_HIV_SPECIFIC_CD8_TCELL_UP | 185 | 7 | 17377 | 282 |
ZNF395,APBA2,SLC39A8,SOX21,NIPSNAP3B,PLK2,PKIA |
| 3.160e-02 | -3.45 | CHANDRAN_METASTASIS_UP | MSigDB lists | CHANDRAN_METASTASIS_UP | 185 | 7 | 17377 | 282 |
TRIM3,P4HA1,GAPDH,RASAL2,DUSP8,ZNF395,RECK |
| 3.160e-02 | -3.45 | GSE10325_CD4_TCELL_VS_MYELOID_UP | MSigDB lists | GSE10325_CD4_TCELL_VS_MYELOID_UP | 185 | 7 | 17377 | 282 |
PRKCA,APBA2,KLHL3,SATB1,SLC39A8,MYC,PLEKHB1 |
| 3.160e-02 | -3.45 | GSE41867_NAIVE_VS_DAY6_LCMV_EFFECTOR_CD8_TCELL_DN | MSigDB lists | GSE41867_NAIVE_VS_DAY6_LCMV_EFFECTOR_CD8_TCELL_DN | 185 | 7 | 17377 | 282 |
ACSL1,RALGPS2,KIF21B,VGLL4,TLR6,SMPDL3A,SPATA13 |
| 3.160e-02 | -3.45 | GSE3982_MAC_VS_TH1_UP | MSigDB lists | GSE3982_MAC_VS_TH1_UP | 185 | 7 | 17377 | 282 |
NDRG2,CEBPA,TLN2,RASAL2,ZHX3,DACT1,WWTR1 |
| 3.160e-02 | -3.45 | GSE2405_0H_VS_1.5H_A_PHAGOCYTOPHILUM_STIM_NEUTROPHIL_UP | MSigDB lists | GSE2405_0H_VS_1.5H_A_PHAGOCYTOPHILUM_STIM_NEUTROPHIL_UP | 185 | 7 | 17377 | 282 |
MAFB,CEBPA,APBA2,TSHR,DSTN,ALDOA,EFNA3 |
| 3.160e-02 | -3.45 | GSE11961_GERMINAL_CENTER_BCELL_DAY7_VS_PLASMA_CELL_DAY7_DN | MSigDB lists | GSE11961_GERMINAL_CENTER_BCELL_DAY7_VS_PLASMA_CELL_DAY7_DN | 185 | 7 | 17377 | 282 |
CCDC122,STRADB,ACSL1,ST14,HSPA2,PTPN6,CAPN5 |
| 3.160e-02 | -3.45 | GSE3982_DC_VS_EFF_MEMORY_CD4_TCELL_UP | MSigDB lists | GSE3982_DC_VS_EFF_MEMORY_CD4_TCELL_UP | 185 | 7 | 17377 | 282 |
CLMN,NDRG2,TNS1,STXBP1,KMO,ABHD6,TBC1D8 |
| 3.160e-02 | -3.45 | GSE17721_0.5H_VS_4H_LPS_BMDC_DN | MSigDB lists | GSE17721_0.5H_VS_4H_LPS_BMDC_DN | 185 | 7 | 17377 | 282 |
RUNX2,PALLD,STXBP1,DYNC1I1,SLC39A8,MPP1,HK2 |
| 3.165e-02 | -3.45 | notochord development | biological process | GO:0030903 | 18 | 2 | 17256 | 270 |
WNT11,COBL |
| 3.165e-02 | -3.45 | regulation of cellular response to vascular endothelial growth factor stimulus | biological process | GO:1902547 | 18 | 2 | 17256 | 270 |
DAB2IP,ADAMTS3 |
| 3.165e-02 | -3.45 | positive regulation of mast cell activation | biological process | GO:0033005 | 18 | 2 | 17256 | 270 |
FGR,STXBP1 |
| 3.165e-02 | -3.45 | activation of NF-kappaB-inducing kinase activity | biological process | GO:0007250 | 18 | 2 | 17256 | 270 |
TNFSF15,TLR6 |
| 3.165e-02 | -3.45 | cell death in response to oxidative stress | biological process | GO:0036473 | 18 | 2 | 17256 | 270 |
PDK1,PRKCD |
| 3.165e-02 | -3.45 | osteoblast development | biological process | GO:0002076 | 18 | 2 | 17256 | 270 |
SATB2,RUNX2 |
| 3.165e-02 | -3.45 | intestinal epithelial cell differentiation | biological process | GO:0060575 | 18 | 2 | 17256 | 270 |
PRDM1,SAV1 |
| 3.165e-02 | -3.45 | positive regulation of autophagy of mitochondrion | biological process | GO:1903599 | 18 | 2 | 17256 | 270 |
BNIP3,HK2 |
| 3.165e-02 | -3.45 | paraxial mesoderm development | biological process | GO:0048339 | 18 | 2 | 17256 | 270 |
EPB41L5,WNT11 |
| 3.165e-02 | -3.45 | small molecule binding | molecular function | GO:0036094 | 2448 | 51 | 17224 | 278 |
RUNX2,ACSL1,ACVR1,BVES,ARL2,KIF5C,RASL11B,ITPR2,ABAT,KIF21B,COLEC10,PRKCA,KMO,RPS6KL1,PRKCD,RASD2,EHD3,GTF2F2,ACTA2,SGK1,MYH15,PDE4D,EPHB6,RAB27B,DNAH5,HSPA2,PARP9,GAPDH,PDK1,CYB5R2,NUAK2,OGDHL,ADCY1,STRADB,ABCC2,ACVR2B,RAB38,SGK2,GRK3,DYRK1B,TRIB3,FGR,PLK2,FMO4,MAP2K6,GNAO1,ALDOA,ERN1,HK2,P4HA1,MAPK13 |
| 3.176e-02 | -3.45 | TFAP2C (transcription factor AP-2 gamma) | protein interactions | 7022 | 17 | 2 | 17029 | 283 |
MYC,KCTD1 |
| 3.176e-02 | -3.45 | ORM1 (orosomucoid 1) | protein interactions | 5004 | 17 | 2 | 17029 | 283 |
TMEM37,BLVRB |
| 3.176e-02 | -3.45 | AZIN1 (antizyme inhibitor 1) | protein interactions | 51582 | 17 | 2 | 17029 | 283 |
KIF5C,ABCC2 |
| 3.176e-02 | -3.45 | FNBP4 (formin binding protein 4) | protein interactions | 23360 | 17 | 2 | 17029 | 283 |
LGR4,PLXNA2 |
| 3.176e-02 | -3.45 | ALG13 (ALG13, UDP-N-acetylglucosaminyltransferase subunit) | protein interactions | 79868 | 17 | 2 | 17029 | 283 |
SAV1,RERE |
| 3.176e-02 | -3.45 | EEF1A1P5 (eukaryotic translation elongation factor 1 alpha 1 pseudogene 5) | protein interactions | 158078 | 17 | 2 | 17029 | 283 |
UBASH3B,GAN |
| 3.176e-02 | -3.45 | MSL3 (MSL complex subunit 3) | protein interactions | 10943 | 17 | 2 | 17029 | 283 |
DYRK1B,PLEKHA1 |
| 3.176e-02 | -3.45 | TSHB (thyroid stimulating hormone beta) | protein interactions | 7252 | 17 | 2 | 17029 | 283 |
TSHR,EPDR1 |
| 3.176e-02 | -3.45 | FOXD3 (forkhead box D3) | protein interactions | 27022 | 17 | 2 | 17029 | 283 |
SATB2,SATB1 |
| 3.176e-02 | -3.45 | FGD6 (FYVE, RhoGEF and PH domain containing 6) | protein interactions | 55785 | 17 | 2 | 17029 | 283 |
ACVR1,PLK2 |
| 3.176e-02 | -3.45 | SFI1 (SFI1 centrin binding protein) | protein interactions | 9814 | 17 | 2 | 17029 | 283 |
RADIL,FAM131C |
| 3.176e-02 | -3.45 | PI4KB (phosphatidylinositol 4-kinase beta) | protein interactions | 5298 | 17 | 2 | 17029 | 283 |
MYC,NCS1 |
| 3.176e-02 | -3.45 | FAM78 | interpro domains | IPR029638 | 2 | 1 | 18492 | 296 |
FAM78B |
| 3.176e-02 | -3.45 | DYNC1I1/DYNC1I2 | interpro domains | IPR025956 | 2 | 1 | 18492 | 296 |
DYNC1I1 |
| 3.176e-02 | -3.45 | Memapsin-like | interpro domains | IPR033874 | 2 | 1 | 18492 | 296 |
BACE1 |
| 3.176e-02 | -3.45 | Talin_cent_sf | interpro domains | IPR036476 | 2 | 1 | 18492 | 296 |
TLN2 |
| 3.176e-02 | -3.45 | Histamine_H3_rcpt | interpro domains | IPR003980 | 2 | 1 | 18492 | 296 |
ZNF219 |
| 3.176e-02 | -3.45 | Runx_central_dom_sf | interpro domains | IPR027384 | 2 | 1 | 18492 | 296 |
RUNX2 |
| 3.176e-02 | -3.45 | LHPP/HDHD2 | interpro domains | IPR006355 | 2 | 1 | 18492 | 296 |
LHPP |
| 3.176e-02 | -3.45 | EXOC6/Sec15 | interpro domains | IPR007225 | 2 | 1 | 18492 | 296 |
EXOC6B |
| 3.176e-02 | -3.45 | Numb_domain | interpro domains | IPR010449 | 2 | 1 | 18492 | 296 |
NUMBL |
| 3.176e-02 | -3.45 | 2-oxogl_dehyd_N | interpro domains | IPR032106 | 2 | 1 | 18492 | 296 |
OGDHL |
| 3.176e-02 | -3.45 | Tyr_Pase_non-rcpt_typ-14/21 | interpro domains | IPR014392 | 2 | 1 | 18492 | 296 |
PTPN21 |
| 3.176e-02 | -3.45 | Numb/numb-like | interpro domains | IPR016698 | 2 | 1 | 18492 | 296 |
NUMBL |
| 3.176e-02 | -3.45 | M28_QC_like | interpro domains | IPR037457 | 2 | 1 | 18492 | 296 |
QPCTL |
| 3.176e-02 | -3.45 | Glyceraldehyde-3-P_DH_1 | interpro domains | IPR006424 | 2 | 1 | 18492 | 296 |
GAPDH |
| 3.176e-02 | -3.45 | GIY-YIG_endonuc | interpro domains | IPR000305 | 2 | 1 | 18492 | 296 |
SLX1B |
| 3.176e-02 | -3.45 | PNRC1/2 | interpro domains | IPR026780 | 2 | 1 | 18492 | 296 |
PNRC1 |
| 3.176e-02 | -3.45 | Atrophin-like | interpro domains | IPR002951 | 2 | 1 | 18492 | 296 |
RERE |
| 3.176e-02 | -3.45 | LIM1_prickle | interpro domains | IPR033725 | 2 | 1 | 18492 | 296 |
PRICKLE2 |
| 3.176e-02 | -3.45 | Talin1/2-RS | interpro domains | IPR037438 | 2 | 1 | 18492 | 296 |
TLN2 |
| 3.176e-02 | -3.45 | CBD_Rasip1/Radil | interpro domains | IPR037983 | 2 | 1 | 18492 | 296 |
RADIL |
| 3.176e-02 | -3.45 | Vinculin-bd_dom | interpro domains | IPR015009 | 2 | 1 | 18492 | 296 |
TLN2 |
| 3.176e-02 | -3.45 | Tbh/DBH | interpro domains | IPR028460 | 2 | 1 | 18492 | 296 |
MOXD1 |
| 3.176e-02 | -3.45 | Lipase_GDXG_HIS_AS | interpro domains | IPR002168 | 2 | 1 | 18492 | 296 |
NCEH1 |
| 3.176e-02 | -3.45 | BACE | interpro domains | IPR009119 | 2 | 1 | 18492 | 296 |
BACE1 |
| 3.176e-02 | -3.45 | TCF7L | interpro domains | IPR028773 | 2 | 1 | 18492 | 296 |
TCF7L1 |
| 3.176e-02 | -3.45 | STK_RPK118-like | interpro domains | IPR035053 | 2 | 1 | 18492 | 296 |
RPS6KL1 |
| 3.176e-02 | -3.45 | C2_Calpain | interpro domains | IPR033884 | 2 | 1 | 18492 | 296 |
CAPN5 |
| 3.176e-02 | -3.45 | N-acyl_aa_amidohydrolase | interpro domains | IPR010159 | 2 | 1 | 18492 | 296 |
ABHD14A-ACY1 |
| 3.176e-02 | -3.45 | Profilin_CS | interpro domains | IPR027310 | 2 | 1 | 18492 | 296 |
PFN2 |
| 3.176e-02 | -3.45 | TFIIF_interaction | interpro domains | IPR011039 | 2 | 1 | 18492 | 296 |
GTF2F2 |
| 3.176e-02 | -3.45 | TMPIT | interpro domains | IPR012926 | 2 | 1 | 18492 | 296 |
TMEM120B |
| 3.176e-02 | -3.45 | NLGN4 | interpro domains | IPR030025 | 2 | 1 | 18492 | 296 |
NLGN4X |
| 3.176e-02 | -3.45 | GlycerAld/Erythrose_P_DH | interpro domains | IPR020831 | 2 | 1 | 18492 | 296 |
GAPDH |
| 3.176e-02 | -3.45 | Neogenin_C | interpro domains | IPR010560 | 2 | 1 | 18492 | 296 |
NEO1 |
| 3.176e-02 | -3.45 | ATPase_V1_Esu | interpro domains | IPR002842 | 2 | 1 | 18492 | 296 |
ATP6V1E2 |
| 3.176e-02 | -3.45 | GlycerAld_3-P_DH_cat | interpro domains | IPR020829 | 2 | 1 | 18492 | 296 |
GAPDH |
| 3.176e-02 | -3.45 | DUF3827 | interpro domains | IPR024606 | 2 | 1 | 18492 | 296 |
KIAA1549 |
| 3.176e-02 | -3.45 | GlycerAld_3-P_DH_AS | interpro domains | IPR020830 | 2 | 1 | 18492 | 296 |
GAPDH |
| 3.176e-02 | -3.45 | CATSPERD/E | interpro domains | IPR028751 | 2 | 1 | 18492 | 296 |
CATSPERE |
| 3.176e-02 | -3.45 | ATPase_V1-cplx_s1su | interpro domains | IPR008388 | 2 | 1 | 18492 | 296 |
ATP6AP1L |
| 3.176e-02 | -3.45 | Neuritin_fam | interpro domains | IPR026144 | 2 | 1 | 18492 | 296 |
NRN1 |
| 3.176e-02 | -3.45 | ASM-like_Pdiesterase_prd | interpro domains | IPR017064 | 2 | 1 | 18492 | 296 |
SMPDL3A |
| 3.176e-02 | -3.45 | FAM198 | interpro domains | IPR029207 | 2 | 1 | 18492 | 296 |
FAM198B |
| 3.176e-02 | -3.45 | ATPase_E_C | interpro domains | IPR038495 | 2 | 1 | 18492 | 296 |
ATP6V1E2 |
| 3.176e-02 | -3.45 | DUF4525 | interpro domains | IPR027833 | 2 | 1 | 18492 | 296 |
CCDC126 |
| 3.176e-02 | -3.45 | Talin_cent | interpro domains | IPR015224 | 2 | 1 | 18492 | 296 |
TLN2 |
| 3.176e-02 | -3.45 | SOUL_haem-bd | interpro domains | IPR006917 | 2 | 1 | 18492 | 296 |
HEBP1 |
| 3.176e-02 | -3.45 | GlycerAld_3-P_DH_NAD(P)-bd | interpro domains | IPR020828 | 2 | 1 | 18492 | 296 |
GAPDH |
| 3.176e-02 | -3.45 | Cordon-bleu_ubiquitin_domain | interpro domains | IPR019025 | 2 | 1 | 18492 | 296 |
COBL |
| 3.176e-02 | -3.45 | VDCC_L_b3su | interpro domains | IPR008079 | 2 | 1 | 18492 | 296 |
CACNB4 |
| 3.176e-02 | -3.45 | Tyr_Pase_non-rcpt_typ-6/11 | interpro domains | IPR012152 | 2 | 1 | 18492 | 296 |
PTPN6 |
| 3.197e-02 | -3.44 | V$TATA_C | MSigDB lists | V$TATA_C | 269 | 9 | 17377 | 282 |
BDNF,PPM1E,KCTD15,RASL11B,SETBP1,BNIP3,PRDM1,SATB1,PKIA |
| 3.198e-02 | -3.44 | TSAI_RESPONSE_TO_IONIZING_RADIATION | MSigDB lists | TSAI_RESPONSE_TO_IONIZING_RADIATION | 146 | 6 | 17377 | 282 |
MAP7,SGK1,DLX2,PTPN6,MYC,DDIT3 |
| 3.202e-02 | -3.44 | glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity | molecular function | GO:0004365 | 2 | 1 | 17224 | 278 |
GAPDH |
| 3.202e-02 | -3.44 | BLOC-2 complex binding | molecular function | GO:0036461 | 2 | 1 | 17224 | 278 |
RAB38 |
| 3.202e-02 | -3.44 | copper-dependent protein binding | molecular function | GO:0032767 | 2 | 1 | 17224 | 278 |
ATOX1 |
| 3.202e-02 | -3.44 | beta-aspartyl-peptidase activity | molecular function | GO:0008798 | 2 | 1 | 17224 | 278 |
BACE1 |
| 3.202e-02 | -3.44 | N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase activity | molecular function | GO:0033842 | 2 | 1 | 17224 | 278 |
B4GALNT3 |
| 3.202e-02 | -3.44 | transcription factor activity, core RNA polymerase II binding | molecular function | GO:0000991 | 2 | 1 | 17224 | 278 |
GTF2F2 |
| 3.202e-02 | -3.44 | activin receptor activity, type II | molecular function | GO:0016362 | 2 | 1 | 17224 | 278 |
ACVR2B |
| 3.202e-02 | -3.44 | phosphorylation-dependent protein binding | molecular function | GO:0140031 | 2 | 1 | 17224 | 278 |
PTPN6 |
| 3.202e-02 | -3.44 | glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity | molecular function | GO:0043891 | 2 | 1 | 17224 | 278 |
GAPDH |
| 3.202e-02 | -3.44 | glutaminyl-peptide cyclotransferase activity | molecular function | GO:0016603 | 2 | 1 | 17224 | 278 |
QPCTL |
| 3.202e-02 | -3.44 | Fc-gamma receptor I complex binding | molecular function | GO:0034988 | 2 | 1 | 17224 | 278 |
FGR |
| 3.202e-02 | -3.44 | thyroid-stimulating hormone receptor activity | molecular function | GO:0004996 | 2 | 1 | 17224 | 278 |
TSHR |
| 3.202e-02 | -3.44 | biliverdin reductase activity | molecular function | GO:0004074 | 2 | 1 | 17224 | 278 |
BLVRB |
| 3.202e-02 | -3.44 | myo-inositol transmembrane transporter activity | molecular function | GO:0005365 | 2 | 1 | 17224 | 278 |
SLC2A13 |
| 3.202e-02 | -3.44 | histone kinase activity (H3-T6 specific) | molecular function | GO:0035403 | 2 | 1 | 17224 | 278 |
PRKCA |
| 3.202e-02 | -3.44 | calcium- and calmodulin-responsive adenylate cyclase activity | molecular function | GO:0008294 | 2 | 1 | 17224 | 278 |
ADCY1 |
| 3.202e-02 | -3.44 | histone demethylase activity (H4-K20 specific) | molecular function | GO:0035575 | 2 | 1 | 17224 | 278 |
KDM7A |
| 3.202e-02 | -3.44 | voltage-gated sodium channel activity involved in Purkinje myocyte action potential | molecular function | GO:0086062 | 2 | 1 | 17224 | 278 |
SCN5A |
| 3.212e-02 | -3.44 | negative regulation of developmental process | biological process | GO:0051093 | 973 | 23 | 17256 | 270 |
PHLDB2,BDNF,MSX1,UBASH3B,EFNA3,MAFB,WWC1,CHADL,WNT11,GAS6,OVOL2,SAV1,IL17D,TRIB3,PLK2,RBPMS2,MYC,WWTR1,DAB2IP,BNIP3,DLX2,DDIT3,GPR161 |
| 3.215e-02 | -3.44 | SQSTM1 (sequestosome 1) | protein interactions | 8878 | 263 | 9 | 17029 | 283 |
TRIB3,KLHL3,MYC,PRKCD,MAPK13,GAS6,STXBP1,FHOD3,EPDR1 |
| 3.224e-02 | -3.43 | GO_CELLULAR_TRANSITION_METAL_ION_HOMEOSTASIS | MSigDB lists | GO_CELLULAR_TRANSITION_METAL_ION_HOMEOSTASIS | 74 | 4 | 17377 | 282 |
SLC40A1,SLC39A8,MYC,ATOX1 |
| 3.227e-02 | -3.43 | LIM_MAMMARY_STEM_CELL_DN | MSigDB lists | LIM_MAMMARY_STEM_CELL_DN | 403 | 12 | 17377 | 282 |
EPCAM,UROS,ST14,PTPN6,BIK,SPATA13,RHPN2,MAPK13,ARRDC4,COBL,MTUS1,TBC1D8 |
| 3.228e-02 | -3.43 | V$HNF1_C | MSigDB lists | V$HNF1_C | 227 | 8 | 17377 | 282 |
ZNF827,MXI1,EEPD1,TNS1,TMEM37,PRDM1,SGK2,NEO1 |
| 3.231e-02 | -3.43 | activation of immune response | biological process | GO:0002253 | 466 | 13 | 17256 | 270 |
FGR,DOCK1,CFHR1,C4A,MAP2K6,PTPN6,PRKCD,INAVA,PLEKHA1,PDE4D,COLEC10,TLR6,GPLD1 |
| 3.238e-02 | -3.43 | FNTA (farnesyltransferase, CAAX box, alpha) | protein interactions | 2339 | 42 | 3 | 17029 | 283 |
EPB41L5,ACVR1,HK2 |
| 3.239e-02 | -3.43 | WARTERS_IR_RESPONSE_5GY | MSigDB lists | WARTERS_IR_RESPONSE_5GY | 43 | 3 | 17377 | 282 |
CHADL,FAM198B,TNFRSF10C |
| 3.239e-02 | -3.43 | BRACHAT_RESPONSE_TO_CAMPTOTHECIN_DN | MSigDB lists | BRACHAT_RESPONSE_TO_CAMPTOTHECIN_DN | 43 | 3 | 17377 | 282 |
GAPDH,ALDOA,BNIP3L |
| 3.239e-02 | -3.43 | GO_PEPTIDYL_THREONINE_MODIFICATION | MSigDB lists | GO_PEPTIDYL_THREONINE_MODIFICATION | 43 | 3 | 17377 | 282 |
ACVR1,PRKCA,PRKCD |
| 3.239e-02 | -3.43 | GALLUZZI_PERMEABILIZE_MITOCHONDRIA | MSigDB lists | GALLUZZI_PERMEABILIZE_MITOCHONDRIA | 43 | 3 | 17377 | 282 |
BNIP3,PMAIP1,PRKCD |
| 3.239e-02 | -3.43 | REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK | MSigDB lists | REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK | 43 | 3 | 17377 | 282 |
ARHGEF11,RASGRF2,TIAM2 |
| 3.239e-02 | -3.43 | ZHAN_MULTIPLE_MYELOMA_CD1_UP | MSigDB lists | ZHAN_MULTIPLE_MYELOMA_CD1_UP | 43 | 3 | 17377 | 282 |
GPR63,TRIB3,TBC1D16 |
| 3.239e-02 | -3.43 | GO_NEGATIVE_REGULATION_OF_MYELOID_LEUKOCYTE_DIFFERENTIATION | MSigDB lists | GO_NEGATIVE_REGULATION_OF_MYELOID_LEUKOCYTE_DIFFERENTIATION | 43 | 3 | 17377 | 282 |
MAFB,UBASH3B,MYC |
| 3.239e-02 | -3.43 | ZHAN_MULTIPLE_MYELOMA_HP_DN | MSigDB lists | ZHAN_MULTIPLE_MYELOMA_HP_DN | 43 | 3 | 17377 | 282 |
LHPP,PRSS16,PKIA |
| 3.239e-02 | -3.43 | MODULE_448 | MSigDB lists | MODULE_448 | 43 | 3 | 17377 | 282 |
BVES,ABHD6,BNIP3L |
| 3.240e-02 | -3.43 | GSE25123_CTRL_VS_IL4_STIM_PPARG_KO_MACROPHAGE_DN | MSigDB lists | GSE25123_CTRL_VS_IL4_STIM_PPARG_KO_MACROPHAGE_DN | 186 | 7 | 17377 | 282 |
CCDC122,ITPR2,IGIP,UBASH3B,CYB5R2,EHD3,NEO1 |
| 3.240e-02 | -3.43 | GSE22935_UNSTIM_VS_24H_MBOVIS_BCG_STIM_MACROPHAGE_UP | MSigDB lists | GSE22935_UNSTIM_VS_24H_MBOVIS_BCG_STIM_MACROPHAGE_UP | 186 | 7 | 17377 | 282 |
RGS17,DUSP8,DYNC1I1,HEBP1,SMPDL3A,ZIC5,HK2 |
| 3.240e-02 | -3.43 | GSE28726_ACT_CD4_TCELL_VS_ACT_NKTCELL_DN | MSigDB lists | GSE28726_ACT_CD4_TCELL_VS_ACT_NKTCELL_DN | 186 | 7 | 17377 | 282 |
SGK1,MXI1,EPHB6,PDE4D,DUSP8,SATB1,DDIT3 |
| 3.240e-02 | -3.43 | GSE2405_HEAT_KILLED_LYSATE_VS_LIVE_A_PHAGOCYTOPHILUM_STIM_NEUTROPHIL_9H_UP | MSigDB lists | GSE2405_HEAT_KILLED_LYSATE_VS_LIVE_A_PHAGOCYTOPHILUM_STIM_NEUTROPHIL_9H_UP | 186 | 7 | 17377 | 282 |
LONRF1,DAB2IP,FGR,PRSS16,MPP1,DSTN,PLEKHB1 |
| 3.240e-02 | -3.43 | GSE4142_NAIVE_VS_MEMORY_BCELL_UP | MSigDB lists | GSE4142_NAIVE_VS_MEMORY_BCELL_UP | 186 | 7 | 17377 | 282 |
KIAA0513,KIF5C,ZNF474,NUMBL,FKBP9,ACVR1,TBC1D8 |
| 3.240e-02 | -3.43 | GSE24634_TREG_VS_TCONV_POST_DAY5_IL4_CONVERSION_DN | MSigDB lists | GSE24634_TREG_VS_TCONV_POST_DAY5_IL4_CONVERSION_DN | 186 | 7 | 17377 | 282 |
MXI1,PLEKHA1,ST14,KLHL3,KMO,DACT1,DDIT3 |
| 3.240e-02 | -3.43 | GSE13484_12H_UNSTIM_VS_YF17D_VACCINE_STIM_PBMC_UP | MSigDB lists | GSE13484_12H_UNSTIM_VS_YF17D_VACCINE_STIM_PBMC_UP | 186 | 7 | 17377 | 282 |
BNIP3,CEBPA,FAM198B,DBP,MPP1,DSTN,BLVRB |
| 3.240e-02 | -3.43 | GSE20366_CD103_POS_VS_NEG_TREG_KLRG1NEG_UP | MSigDB lists | GSE20366_CD103_POS_VS_NEG_TREG_KLRG1NEG_UP | 186 | 7 | 17377 | 282 |
GPR63,ZNF474,OVOL2,RALGPS2,CYB5R2,WWTR1,FHOD3 |
| 3.240e-02 | -3.43 | GSE7219_WT_VS_NIK_NFKB2_KO_LPS_AND_ANTI_CD40_STIM_DC_DN | MSigDB lists | GSE7219_WT_VS_NIK_NFKB2_KO_LPS_AND_ANTI_CD40_STIM_DC_DN | 186 | 7 | 17377 | 282 |
ARHGAP26,DISP1,KCTD15,RUNX2,IGIP,ABHD6,ERN1 |
| 3.240e-02 | -3.43 | GSE6674_PL2_3_VS_ANTI_IGM_AND_CPG_STIM_BCELL_DN | MSigDB lists | GSE6674_PL2_3_VS_ANTI_IGM_AND_CPG_STIM_BCELL_DN | 186 | 7 | 17377 | 282 |
STRADB,NDRG2,NRN1,MXI1,PFN2,MYC,CAPN5 |
| 3.240e-02 | -3.43 | GSE3039_CD4_TCELL_VS_B2_BCELL_UP | MSigDB lists | GSE3039_CD4_TCELL_VS_B2_BCELL_UP | 186 | 7 | 17377 | 282 |
MAFB,ARHGAP26,PPM1E,CPNE2,PDE4D,BACE1,SMPDL3A |
| 3.240e-02 | -3.43 | GSE2770_IL12_VS_TGFB_AND_IL12_TREATED_ACT_CD4_TCELL_48H_UP | MSigDB lists | GSE2770_IL12_VS_TGFB_AND_IL12_TREATED_ACT_CD4_TCELL_48H_UP | 186 | 7 | 17377 | 282 |
DAB2IP,PLEKHA1,ACSL1,SLC30A4,KMO,ST14,SLC39A8 |
| 3.240e-02 | -3.43 | GSE17721_LPS_VS_GARDIQUIMOD_12H_BMDC_UP | MSigDB lists | GSE17721_LPS_VS_GARDIQUIMOD_12H_BMDC_UP | 186 | 7 | 17377 | 282 |
DAB2IP,IFT81,TMEM37,KIF21B,PNRC1,CACNB4,HK2 |
| 3.240e-02 | -3.43 | GSE7460_FOXP3_MUT_VS_WT_ACT_WITH_TGFB_TCONV_DN | MSigDB lists | GSE7460_FOXP3_MUT_VS_WT_ACT_WITH_TGFB_TCONV_DN | 186 | 7 | 17377 | 282 |
PRKCA,TBC1D16,RECK,UBASH3B,MTUS1,RERE,CYP4V2 |
| 3.242e-02 | -3.43 | regulation of sequestering of calcium ion | biological process | GO:0051282 | 113 | 5 | 17256 | 270 |
ITPR2,PDE4D,PTPN6,UBASH3B,DDIT3 |
| 3.246e-02 | -3.43 | GO_REGULATION_OF_CALCIUM_ION_TRANSMEMBRANE_TRANSPORT | MSigDB lists | GO_REGULATION_OF_CALCIUM_ION_TRANSMEMBRANE_TRANSPORT | 109 | 5 | 17377 | 282 |
PDE4D,CACNB4,PTPN6,HSPA2,UBASH3B |
| 3.246e-02 | -3.43 | CHARAFE_BREAST_CANCER_BASAL_VS_MESENCHYMAL_UP | MSigDB lists | CHARAFE_BREAST_CANCER_BASAL_VS_MESENCHYMAL_UP | 109 | 5 | 17377 | 282 |
OVOL2,ACSL1,ST14,MARVELD2,PTPN6 |
| 3.247e-02 | -3.43 | cellular response to inorganic substance | biological process | GO:0071241 | 193 | 7 | 17256 | 270 |
CPNE2,CEBPA,SLC40A1,BNIP3,SCN5A,ADCY1,GPLD1 |
| 3.249e-02 | -3.43 | positive regulation of nucleobase-containing compound metabolic process | biological process | GO:0045935 | 1736 | 37 | 17256 | 270 |
RUNX2,ZNF516,ACVR1,LGR4,ARHGEF11,FBXO4,SLX1B,CEBPA,OVOL2,ZNF219,KDM7A,EPCAM,MYC,PRKCD,GTF2F2,EBF4,DAB2IP,FANK1,TSHR,BARX1,GPR161,PARP9,SLC40A1,MSX1,SOX21,WWC1,MAFB,WNT11,SATB2,RERE,DYRK1B,WWTR1,ERN1,DBP,DLX2,SMYD3,DDIT3 |
| 3.249e-02 | -3.43 | Photodynamic therapy-induced HIF-1 survival signaling | WikiPathways | WP3614 | 37 | 3 | 5312 | 101 |
BNIP3,PMAIP1,BNIP3L |
| 3.250e-02 | -3.43 | cell cycle arrest | biological process | GO:0007050 | 152 | 6 | 17256 | 270 |
STRADB,GAS6,MYC,MAP2K6,DDIT3,ERN1 |
| 3.261e-02 | -3.42 | regulation of hemostasis | biological process | GO:1900046 | 77 | 4 | 17256 | 270 |
ABAT,PRKCA,UBASH3B,PRKCD |
| 3.261e-02 | -3.42 | regulation of blood coagulation | biological process | GO:0030193 | 77 | 4 | 17256 | 270 |
ABAT,PRKCA,UBASH3B,PRKCD |
| 3.261e-02 | -3.42 | nephron tubule development | biological process | GO:0072080 | 77 | 4 | 17256 | 270 |
WNT11,LGR4,KLHL3,MYC |
| 3.270e-02 | -3.42 | DAP12 signaling | REACTOME pathways | R-HSA-2424491 | 356 | 10 | 10287 | 148 |
IL17RD,TRIB3,RASAL2,DUSP8,RASGRF2,PRKCD,ADCY1,DAB2IP,ITPR2,PRKCA |
| 3.276e-02 | -3.42 | VEGFR2 mediated cell proliferation | REACTOME pathways | R-HSA-5218921 | 258 | 8 | 10287 | 148 |
IL17RD,RASAL2,DUSP8,RASGRF2,PRKCD,DAB2IP,ITPR2,PRKCA |
| 3.282e-02 | -3.42 | thyroid-carcinoma | COSMIC cancer mutations | thyroid-carcinoma | 4219 | 82 | 17385 | 281 |
ARHGAP26,LGR4,RASAL2,RECK,C4A,FAM131C,PTPN21,PLXNA2,RHPN2,ITPR2,ABAT,COLEC10,ABHD4,ABHD6,HMCN1,TIAM2,EPCAM,TMEM53,ZNF521,TMEM143,MYH15,PDE4D,TMEM37,TLN2,DNAH5,TSHR,HSPA2,C3orf67,PHLDB2,CYB5R2,ADCY1,WNT11,TNS1,ABCC2,ACVR2B,TBC1D16,SPNS1,DYRK1B,TCF7L1,LMLN,PLK2,WFS1,RASGRF2,PLEKHG1,DISP1,COBL,LONRF1,SCN5A,ZHX3,UBASH3B,SETBP1,DYNC1I1,FHOD3,NEO1,IL17D,RALGPS2,GPR155,MYC,RASD2,GTF2F2,PRICKLE2,SGK1,STXBP1,PARP9,TMC7,SLC40A1,OGDHL,PPFIA4,WWC1,B4GALNT3,RERE,GPLD1,TRIB3,FGR,ADAMTS3,GNAO1,MAP2K6,LRRIQ3,HK2,KIAA0513,MYOM2,IQSEC2 |
| 3.289e-02 | -3.41 | Validated targets of C-MYC transcriptional repression | Pathway Interaction DB | myc_represspathway | 61 | 4 | 2226 | 45 |
NDRG2,CEBPA,MYC,DDIT3 |
| 3.290e-02 | -3.41 | ACACTGG,MIR-199A,MIR-199B | MSigDB lists | ACACTGG,MIR-199A,MIR-199B | 147 | 6 | 17377 | 282 |
MAFB,PXN,PDE4D,KIAA0355,KLHL3,HMCN1 |
| 3.292e-02 | -3.41 | inorganic cation transmembrane transporter activity | molecular function | GO:0022890 | 596 | 16 | 17224 | 278 |
SLC40A1,SCN5A,TMEM63C,SLC30A4,SLC9C1,SLC39A8,ATOX1,ATP6V1E2,SLC25A28,ITPR2,GAS6,TMEM37,SLC2A13,CACNB4,ATP6AP1L,NCS1 |
| 3.296e-02 | -3.41 | svp (seven up) | protein interactions | 41491 | 2 | 1 | 17029 | 283 |
RERE |
| 3.296e-02 | -3.41 | SPANXC (SPANX family member C) | protein interactions | 64663 | 2 | 1 | 17029 | 283 |
SETBP1 |
| 3.296e-02 | -3.41 | TMC5 (transmembrane channel like 5) | protein interactions | 79838 | 2 | 1 | 17029 | 283 |
NUMBL |
| 3.296e-02 | -3.41 | GRM6 (glutamate metabotropic receptor 6) | protein interactions | 2916 | 2 | 1 | 17029 | 283 |
GNAO1 |
| 3.296e-02 | -3.41 | ZDHHC2 (zinc finger DHHC-type containing 2) | protein interactions | 51201 | 2 | 1 | 17029 | 283 |
MAFB |
| 3.296e-02 | -3.41 | Rab17 (RAB17, member RAS oncogene family) | protein interactions | 19329 | 2 | 1 | 17029 | 283 |
ACVR1 |
| 3.296e-02 | -3.41 | HS3ST1 (heparan sulfate-glucosamine 3-sulfotransferase 1) | protein interactions | 9957 | 2 | 1 | 17029 | 283 |
LGR4 |
| 3.296e-02 | -3.41 | CLEC4A (C-type lectin domain family 4 member A) | protein interactions | 50856 | 2 | 1 | 17029 | 283 |
PTPN6 |
| 3.296e-02 | -3.41 | COL6A3 (collagen type VI alpha 3 chain) | protein interactions | 1293 | 2 | 1 | 17029 | 283 |
GAN |
| 3.296e-02 | -3.41 | TULP1 (tubby like protein 1) | protein interactions | 7287 | 2 | 1 | 17029 | 283 |
ARHGAP26 |
| 3.296e-02 | -3.41 | PKHD1 (PKHD1, fibrocystin/polyductin) | protein interactions | 5314 | 2 | 1 | 17029 | 283 |
LGR4 |
| 3.296e-02 | -3.41 | Tanc2 (tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2) | protein interactions | 303599 | 2 | 1 | 17029 | 283 |
PRICKLE2 |
| 3.296e-02 | -3.41 | TMEM184C (transmembrane protein 184C) | protein interactions | 55751 | 2 | 1 | 17029 | 283 |
SGK1 |
| 3.296e-02 | -3.41 | ANKRD36B (ankyrin repeat domain 36B) | protein interactions | 57730 | 2 | 1 | 17029 | 283 |
GAN |
| 3.296e-02 | -3.41 | MPIG6B (megakaryocyte and platelet inhibitory receptor G6b) | protein interactions | 80739 | 2 | 1 | 17029 | 283 |
PTPN6 |
| 3.296e-02 | -3.41 | numb (numb) | protein interactions | 34263 | 2 | 1 | 17029 | 283 |
PRKCA |
| 3.296e-02 | -3.41 | Fcho1 (FCH domain only 1) | protein interactions | 74015 | 2 | 1 | 17029 | 283 |
ACVR1 |
| 3.296e-02 | -3.41 | KIR2DL5A (killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 5A) | protein interactions | 57292 | 2 | 1 | 17029 | 283 |
PTPN6 |
| 3.296e-02 | -3.41 | Rpl4 (ribosomal protein L4) | protein interactions | 64302 | 2 | 1 | 17029 | 283 |
PRICKLE2 |
| 3.296e-02 | -3.41 | Dact3 (dishevelled-binding antagonist of beta-catenin 3) | protein interactions | 499088 | 2 | 1 | 17029 | 283 |
DACT1 |
| 3.296e-02 | -3.41 | Bcr (BCR, RhoGEF and GTPase activating protein) | protein interactions | 309696 | 2 | 1 | 17029 | 283 |
PRICKLE2 |
| 3.296e-02 | -3.41 | CFHR2 (complement factor H related 2) | protein interactions | 3080 | 2 | 1 | 17029 | 283 |
CFHR1 |
| 3.296e-02 | -3.41 | IL1RAPL1 (interleukin 1 receptor accessory protein like 1) | protein interactions | 11141 | 2 | 1 | 17029 | 283 |
NCS1 |
| 3.296e-02 | -3.41 | Stx8 (syntaxin 8) | protein interactions | 55943 | 2 | 1 | 17029 | 283 |
ACVR1 |
| 3.296e-02 | -3.41 | rnf-5 (RING finger protein 5;RiNg Finger protein) | protein interactions | 175532 | 2 | 1 | 17029 | 283 |
PXN |
| 3.296e-02 | -3.41 | MDP1 (magnesium dependent phosphatase 1) | protein interactions | 145553 | 2 | 1 | 17029 | 283 |
DSTN |
| 3.296e-02 | -3.41 | DNAH8 (dynein axonemal heavy chain 8) | protein interactions | 1769 | 2 | 1 | 17029 | 283 |
GAN |
| 3.296e-02 | -3.41 | Tanc1 (tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1) | protein interactions | 311055 | 2 | 1 | 17029 | 283 |
PRICKLE2 |
| 3.296e-02 | -3.41 | Eif4e (eukaryotic translation initiation factor 4E) | protein interactions | 13684 | 2 | 1 | 17029 | 283 |
MYC |
| 3.296e-02 | -3.41 | Rpl23 (ribosomal protein L23) | protein interactions | 29282 | 2 | 1 | 17029 | 283 |
PRICKLE2 |
| 3.296e-02 | -3.41 | LOC344382 (serine/threonine kinase receptor associated protein pseudogene) | protein interactions | 344382 | 2 | 1 | 17029 | 283 |
SLX1B |
| 3.296e-02 | -3.41 | LIM2 (lens intrinsic membrane protein 2) | protein interactions | 3982 | 2 | 1 | 17029 | 283 |
ACTA2 |
| 3.296e-02 | -3.41 | TEF (TEF, PAR bZIP transcription factor) | protein interactions | 7008 | 2 | 1 | 17029 | 283 |
DBP |
| 3.296e-02 | -3.41 | SLC1A6 (solute carrier family 1 member 6) | protein interactions | 6511 | 2 | 1 | 17029 | 283 |
ARHGEF11 |
| 3.296e-02 | -3.41 | Ptk2 (PTK2 protein tyrosine kinase 2) | protein interactions | 14083 | 2 | 1 | 17029 | 283 |
PXN |
| 3.296e-02 | -3.41 | CEMIP (cell migration inducing hyaluronidase 1) | protein interactions | 57214 | 2 | 1 | 17029 | 283 |
PLXNA2 |
| 3.296e-02 | -3.41 | NSUN7 (NOP2/Sun RNA methyltransferase family member 7) | protein interactions | 79730 | 2 | 1 | 17029 | 283 |
PTPN6 |
| 3.296e-02 | -3.41 | LRRC37A11P (leucine rich repeat containing 37 member A11, pseudogene) | protein interactions | 342666 | 2 | 1 | 17029 | 283 |
SETBP1 |
| 3.296e-02 | -3.41 | Ntrk2 (neurotrophic receptor tyrosine kinase 2) | protein interactions | 25054 | 2 | 1 | 17029 | 283 |
BDNF |
| 3.296e-02 | -3.41 | Plek (pleckstrin) | protein interactions | 56193 | 2 | 1 | 17029 | 283 |
ACVR1 |
| 3.296e-02 | -3.41 | Git1 (GIT ArfGAP 1) | protein interactions | 83709 | 2 | 1 | 17029 | 283 |
PXN |
| 3.296e-02 | -3.41 | ARMH1 (armadillo-like helical domain containing 1) | protein interactions | 339541 | 2 | 1 | 17029 | 283 |
ABAT |
| 3.296e-02 | -3.41 | Siglece (sialic acid binding Ig-like lectin E) | protein interactions | 83382 | 2 | 1 | 17029 | 283 |
PTPN6 |
| 3.296e-02 | -3.41 | KLRB1 (killer cell lectin like receptor B1) | protein interactions | 3820 | 2 | 1 | 17029 | 283 |
PTPN6 |
| 3.296e-02 | -3.41 | Fkbp4 (FK506 binding protein 4) | protein interactions | 14228 | 2 | 1 | 17029 | 283 |
ACVR1 |
| 3.296e-02 | -3.41 | Atf2 (activating transcription factor 2) | protein interactions | 81647 | 2 | 1 | 17029 | 283 |
CEBPA |
| 3.296e-02 | -3.41 | CFAP44 (cilia and flagella associated protein 44) | protein interactions | 55779 | 2 | 1 | 17029 | 283 |
GAN |
| 3.296e-02 | -3.41 | GPR101 (G protein-coupled receptor 101) | protein interactions | 83550 | 2 | 1 | 17029 | 283 |
GAN |
| 3.296e-02 | -3.41 | Usp9x (ubiquitin specific peptidase 9, X-linked) | protein interactions | 363445 | 2 | 1 | 17029 | 283 |
PRICKLE2 |
| 3.296e-02 | -3.41 | Cad (carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase) | protein interactions | 24240 | 2 | 1 | 17029 | 283 |
PRICKLE2 |
| 3.296e-02 | -3.41 | SPANXD (SPANX family member D) | protein interactions | 64648 | 2 | 1 | 17029 | 283 |
SETBP1 |
| 3.296e-02 | -3.41 | Usp21 (ubiquitin specific peptidase 21) | protein interactions | 30941 | 2 | 1 | 17029 | 283 |
ACVR1 |
| 3.296e-02 | -3.41 | EPX (eosinophil peroxidase) | protein interactions | 8288 | 2 | 1 | 17029 | 283 |
GAN |
| 3.305e-02 | -3.41 | GO_POSITIVE_REGULATION_OF_TRANSFERASE_ACTIVITY | MSigDB lists | GO_POSITIVE_REGULATION_OF_TRANSFERASE_ACTIVITY | 593 | 16 | 17377 | 282 |
TRIB3,FGR,ACSL1,MAP2K6,PRKCD,ERN1,ADCY1,STRADB,TNFSF15,WNT11,DAB2IP,ACVR2B,GAS6,ARRDC4,TLR6,HSPA2 |
| 3.306e-02 | -3.41 | NK-T_cell_lymphoma | COSMIC cancer mutations | NK-T_cell_lymphoma | 229 | 8 | 17385 | 281 |
P4HA1,WWC1,BNIP3,PRDM1,FAM198B,DNAH5,SRGAP1,PLXNA2 |
| 3.318e-02 | -3.41 | regulation of release of cytochrome c from mitochondria | biological process | GO:0090199 | 45 | 3 | 17256 | 270 |
BNIP3,PMAIP1,BIK |
| 3.321e-02 | -3.40 | GSE360_HIGH_VS_LOW_DOSE_B_MALAYI_MAC_UP | MSigDB lists | GSE360_HIGH_VS_LOW_DOSE_B_MALAYI_MAC_UP | 187 | 7 | 17377 | 282 |
QSOX1,RGS16,DBP,GAS6,ZHX3,PLEKHB1,ATOX1 |
| 3.321e-02 | -3.40 | GSE36392_MAC_VS_NEUTROPHIL_IL25_TREATED_LUNG_DN | MSigDB lists | GSE36392_MAC_VS_NEUTROPHIL_IL25_TREATED_LUNG_DN | 187 | 7 | 17377 | 282 |
RASL11B,MXI1,RADIL,KIAA1549,WWTR1,FHOD3,HK2 |
| 3.321e-02 | -3.40 | GSE3920_UNTREATED_VS_IFNB_TREATED_ENDOTHELIAL_CELL_UP | MSigDB lists | GSE3920_UNTREATED_VS_IFNB_TREATED_ENDOTHELIAL_CELL_UP | 187 | 7 | 17377 | 282 |
TMC7,GAS6,RUNX2,HEBP1,MTUS1,RERE,BNIP3L |
| 3.321e-02 | -3.40 | GSE10273_HIGH_VS_LOW_IL7_TREATED_IRF4_8_NULL_PRE_BCELL_UP | MSigDB lists | GSE10273_HIGH_VS_LOW_IL7_TREATED_IRF4_8_NULL_PRE_BCELL_UP | 187 | 7 | 17377 | 282 |
LONRF1,PHLDB2,SLC40A1,PXN,DOCK1,RECK,CYP4V2 |
| 3.321e-02 | -3.40 | GSE17721_CTRL_VS_POLYIC_12H_BMDC_DN | MSigDB lists | GSE17721_CTRL_VS_POLYIC_12H_BMDC_DN | 187 | 7 | 17377 | 282 |
RHPN2,NDRG2,RAB38,PALLD,STXBP1,CBLN1,WFS1 |
| 3.321e-02 | -3.40 | GSE27786_NKCELL_VS_NEUTROPHIL_UP | MSigDB lists | GSE27786_NKCELL_VS_NEUTROPHIL_UP | 187 | 7 | 17377 | 282 |
DZANK1,C2orf88,PRDM1,PTPN6,EHD3,GTF2F2,PARP9 |
| 3.321e-02 | -3.40 | EGFR_UP.V1_DN | MSigDB lists | EGFR_UP.V1_DN | 187 | 7 | 17377 | 282 |
KIF5C,MAFB,SATB2,OVOL2,HERC6,SLC39A8,HEBP1 |
| 3.321e-02 | -3.40 | GSE7852_LN_VS_THYMUS_TREG_UP | MSigDB lists | GSE7852_LN_VS_THYMUS_TREG_UP | 187 | 7 | 17377 | 282 |
MAP7,KIF5C,PRKCA,UBASH3B,MARVELD2,CYP4V2,NUAK2 |
| 3.321e-02 | -3.40 | GSE43955_10H_VS_30H_ACT_CD4_TCELL_WITH_TGFB_IL6_DN | MSigDB lists | GSE43955_10H_VS_30H_ACT_CD4_TCELL_WITH_TGFB_IL6_DN | 187 | 7 | 17377 | 282 |
DYRK1B,MSX1,ITPR2,DLX6,PLK2,WWTR1,HK2 |
| 3.321e-02 | -3.40 | V$FOXD3_01 | MSigDB lists | V$FOXD3_01 | 187 | 7 | 17377 | 282 |
SGK1,PRICKLE2,KCTD15,RALGPS2,SLC39A8,GNAO1,NEO1 |
| 3.321e-02 | -3.40 | GSE5503_LIVER_DC_VS_SPLEEN_DC_ACTIVATED_ALLOGENIC_TCELL_UP | MSigDB lists | GSE5503_LIVER_DC_VS_SPLEEN_DC_ACTIVATED_ALLOGENIC_TCELL_UP | 187 | 7 | 17377 | 282 |
ARL2,IFT81,IQSEC2,SLC30A4,RNF122,HEBP1,CAPN5 |
| 3.321e-02 | -3.40 | GSE33424_CD161_INT_VS_NEG_CD8_TCELL_DN | MSigDB lists | GSE33424_CD161_INT_VS_NEG_CD8_TCELL_DN | 187 | 7 | 17377 | 282 |
FGR,RUNX2,ZNF395,PFN2,GPR155,UBASH3B,PHC1 |
| 3.321e-02 | -3.40 | GSE3982_MAC_VS_NKCELL_UP | MSigDB lists | GSE3982_MAC_VS_NKCELL_UP | 187 | 7 | 17377 | 282 |
GPR63,TNS1,RGS16,ACSL1,STXBP1,HEBP1,WWTR1 |
| 3.321e-02 | -3.40 | GSE8921_UNSTIM_VS_TLR1_2_STIM_MONOCYTE_6H_UP | MSigDB lists | GSE8921_UNSTIM_VS_TLR1_2_STIM_MONOCYTE_6H_UP | 187 | 7 | 17377 | 282 |
P4HA1,NDRG2,SLC36A4,PJA1,RALGPS2,SATB1,ARHGEF11 |
| 3.321e-02 | -3.40 | GSE9650_NAIVE_VS_EXHAUSTED_CD8_TCELL_UP | MSigDB lists | GSE9650_NAIVE_VS_EXHAUSTED_CD8_TCELL_UP | 187 | 7 | 17377 | 282 |
P4HA1,SGK1,SPNS1,RALGPS2,SATB1,PTPN6,RERE |
| 3.321e-02 | -3.40 | GSE6875_TCONV_VS_FOXP3_KO_TREG_DN | MSigDB lists | GSE6875_TCONV_VS_FOXP3_KO_TREG_DN | 187 | 7 | 17377 | 282 |
SLC36A4,UROS,CACNB4,WFS1,ERN1,SPATA13,SRGAP1 |
| 3.321e-02 | -3.40 | GSE20366_EX_VIVO_VS_HOMEOSTATIC_CONVERSION_NAIVE_CD4_TCELL_DN | MSigDB lists | GSE20366_EX_VIVO_VS_HOMEOSTATIC_CONVERSION_NAIVE_CD4_TCELL_DN | 187 | 7 | 17377 | 282 |
TRIM3,ARHGAP28,FKBP9,SATB2,TMEM120B,CYP4V2,GPLD1 |
| 3.321e-02 | -3.40 | GSE29949_CD8_POS_DC_SPLEEN_VS_DC_BRAIN_DN | MSigDB lists | GSE29949_CD8_POS_DC_SPLEEN_VS_DC_BRAIN_DN | 187 | 7 | 17377 | 282 |
IQCK,BDNF,ACVR2B,GAPDH,SLC30A4,KMO,PLXNA2 |
| 3.321e-02 | -3.40 | GO_MESENCHYME_DEVELOPMENT | MSigDB lists | GO_MESENCHYME_DEVELOPMENT | 187 | 7 | 17377 | 282 |
EPB41L5,ACTA2,WNT11,MSX1,ACVR1,OVOL2,WWTR1 |
| 3.321e-02 | -3.40 | GSE17301_CTRL_VS_48H_ACD3_ACD28_IFNA5_STIM_CD8_TCELL_UP | MSigDB lists | GSE17301_CTRL_VS_48H_ACD3_ACD28_IFNA5_STIM_CD8_TCELL_UP | 187 | 7 | 17377 | 282 |
MXI1,GAS6,KMO,GPR155,MPP1,ERN1,RERE |
| 3.321e-02 | -3.40 | GSE17721_CTRL_VS_PAM3CSK4_0.5H_BMDC_DN | MSigDB lists | GSE17721_CTRL_VS_PAM3CSK4_0.5H_BMDC_DN | 187 | 7 | 17377 | 282 |
MAPK13,IFT81,WNT11,LHPP,STXBP1,WFS1,ALDOA |
| 3.322e-02 | -3.40 | LIPASE_GDXG_HIS | prosite domains | PS01173 | 2 | 1 | 12060 | 202 |
NCEH1 |
| 3.322e-02 | -3.40 | PROFILIN | prosite domains | PS00414 | 2 | 1 | 12060 | 202 |
PFN2 |
| 3.322e-02 | -3.40 | ARGE_DAPE_CPG2_1 | prosite domains | PS00758 | 2 | 1 | 12060 | 202 |
ABHD14A-ACY1 |
| 3.322e-02 | -3.40 | GAPDH | prosite domains | PS00071 | 2 | 1 | 12060 | 202 |
GAPDH |
| 3.322e-02 | -3.40 | GIY_YIG | prosite domains | PS50164 | 2 | 1 | 12060 | 202 |
SLX1B |
| 3.324e-02 | -3.40 | DYNLL1 (dynein light chain LC8-type 1) | protein interactions | 8655 | 223 | 8 | 17029 | 283 |
DZANK1,DYRK1B,PHLDB2,GAPDH,ALDOA,WWC1,DYNC1I1,PKIA |
| 3.327e-02 | -3.40 | BMPR1B (bone morphogenetic protein receptor type 1B) | protein interactions | 658 | 73 | 4 | 17029 | 283 |
RAB38,RASD2,PLEKHB1,SRGAP1 |
| 3.327e-02 | -3.40 | SCGB1D1 (secretoglobin family 1D member 1) | protein interactions | 10648 | 73 | 4 | 17029 | 283 |
CCDC148,MOXD1,EPDR1,PLXNA2 |
| 3.340e-02 | -3.40 | cell junction assembly | biological process | GO:0034329 | 153 | 6 | 17256 | 270 |
ARL2,WNT11,TNS1,TLN2,PRKCA,MARVELD2 |
| 3.357e-02 | -3.39 | GSE32901_TH1_VS_TH17_NEG_CD4_TCELL_DN | MSigDB lists | GSE32901_TH1_VS_TH17_NEG_CD4_TCELL_DN | 110 | 5 | 17377 | 282 |
CLMN,ARL2,TMOD2,GPR137C,DSTN |
| 3.364e-02 | -3.39 | CTCCAAG,MIR-432 | MSigDB lists | CTCCAAG,MIR-432 | 75 | 4 | 17377 | 282 |
DAB2IP,KIAA0355,BACE1,EHD3 |
| 3.364e-02 | -3.39 | GO_MULTICELLULAR_ORGANISM_GROWTH | MSigDB lists | GO_MULTICELLULAR_ORGANISM_GROWTH | 75 | 4 | 17377 | 282 |
PLEKHA1,PDE4D,APBA2,WWTR1 |
| 3.364e-02 | -3.39 | YAMASHITA_LIVER_CANCER_STEM_CELL_DN | MSigDB lists | YAMASHITA_LIVER_CANCER_STEM_CELL_DN | 75 | 4 | 17377 | 282 |
MAPK13,ACSL1,FMO4,PRKCD |
| 3.370e-02 | -3.39 | YTATTTTNR_V$MEF2_02 | MSigDB lists | YTATTTTNR_V$MEF2_02 | 643 | 17 | 17377 | 282 |
ARHGAP26,BDNF,PPM1E,MXI1,RASAL2,SLC30A4,KIAA0355,GNAO1,DACT1,ZIC5,PTPN21,P4HA1,STRADB,PRDM1,PALLD,DYNC1I1,GPLD1 |
| 3.374e-02 | -3.39 | V$HIF1_Q5 | MSigDB lists | V$HIF1_Q5 | 229 | 8 | 17377 | 282 |
CCDC126,ZNF827,RGS16,PPM1E,GAPDH,P4HA1,HPCAL4,NT5DC2 |
| 3.382e-02 | -3.39 | Glutamatergic synapse | KEGG pathways | hsa04724 | 114 | 5 | 7161 | 113 |
ITPR2,PRKCA,GRK3,GNAO1,ADCY1 |
| 3.382e-02 | -3.39 | Glutamatergic synapse | KEGG pathways | ko04724 | 114 | 5 | 7161 | 113 |
ITPR2,PRKCA,GRK3,GNAO1,ADCY1 |
| 3.384e-02 | -3.39 | BIOCARTA_CARDIACEGF_PATHWAY | MSigDB lists | BIOCARTA_CARDIACEGF_PATHWAY | 18 | 2 | 17377 | 282 |
PRKCA,MYC |
| 3.384e-02 | -3.39 | STEIN_ESTROGEN_RESPONSE_NOT_VIA_ESRRA | MSigDB lists | STEIN_ESTROGEN_RESPONSE_NOT_VIA_ESRRA | 18 | 2 | 17377 | 282 |
ABAT,SLC39A8 |
| 3.384e-02 | -3.39 | MAINA_VHL_TARGETS_DN | MSigDB lists | MAINA_VHL_TARGETS_DN | 18 | 2 | 17377 | 282 |
BNIP3,MXI1 |
| 3.384e-02 | -3.39 | MAHADEVAN_RESPONSE_TO_MP470_DN | MSigDB lists | MAHADEVAN_RESPONSE_TO_MP470_DN | 18 | 2 | 17377 | 282 |
MYC,DDIT3 |
| 3.384e-02 | -3.39 | BIOCARTA_TEL_PATHWAY | MSigDB lists | BIOCARTA_TEL_PATHWAY | 18 | 2 | 17377 | 282 |
PRKCA,MYC |
| 3.384e-02 | -3.39 | GO_CELL_DEATH_IN_RESPONSE_TO_OXIDATIVE_STRESS | MSigDB lists | GO_CELL_DEATH_IN_RESPONSE_TO_OXIDATIVE_STRESS | 18 | 2 | 17377 | 282 |
PDK1,PRKCD |
| 3.384e-02 | -3.39 | REACTOME_ACTIVATED_AMPK_STIMULATES_FATTY_ACID_OXIDATION_IN_MUSCLE | MSigDB lists | REACTOME_ACTIVATED_AMPK_STIMULATES_FATTY_ACID_OXIDATION_IN_MUSCLE | 18 | 2 | 17377 | 282 |
STRADB,ACSL1 |
| 3.384e-02 | -3.39 | KORKOLA_YOLK_SAC_TUMOR_UP | MSigDB lists | KORKOLA_YOLK_SAC_TUMOR_UP | 18 | 2 | 17377 | 282 |
GAPDH,PTPN6 |
| 3.384e-02 | -3.39 | GO_OSTEOBLAST_DEVELOPMENT | MSigDB lists | GO_OSTEOBLAST_DEVELOPMENT | 18 | 2 | 17377 | 282 |
SATB2,RUNX2 |
| 3.385e-02 | -3.39 | GSE4590_PRE_BCELL_VS_LARGE_PRE_BCELL_UP | MSigDB lists | GSE4590_PRE_BCELL_VS_LARGE_PRE_BCELL_UP | 148 | 6 | 17377 | 282 |
QSOX1,TANC2,SLC30A4,SATB1,ABHD6,HEBP1 |
| 3.385e-02 | -3.39 | GSE13547_CTRL_VS_ANTI_IGM_STIM_ZFX_KO_BCELL_12H_DN | MSigDB lists | GSE13547_CTRL_VS_ANTI_IGM_STIM_ZFX_KO_BCELL_12H_DN | 148 | 6 | 17377 | 282 |
PLEKHA1,PDK1,RALGPS2,RNF122,MYC,RERE |
| 3.385e-02 | -3.39 | GSE3720_LPS_VS_PMA_STIM_VD2_GAMMADELTA_TCELL_DN | MSigDB lists | GSE3720_LPS_VS_PMA_STIM_VD2_GAMMADELTA_TCELL_DN | 148 | 6 | 17377 | 282 |
FKBP9,BDNF,GAS6,SATB1,EPDR1,PHC1 |
| 3.385e-02 | -3.39 | RUIZ_TNC_TARGETS_UP | MSigDB lists | RUIZ_TNC_TARGETS_UP | 148 | 6 | 17377 | 282 |
ARHGAP28,MAFB,PNRC1,VGLL4,PLK2,BNIP3L |
| 3.396e-02 | -3.38 | negative regulation of MAP kinase activity | biological process | GO:0043407 | 78 | 4 | 17256 | 270 |
DAB2IP,DUSP8,PTPN6,PRKCD |
| 3.396e-02 | -3.38 | regulation of mitochondrial membrane permeability | biological process | GO:0046902 | 78 | 4 | 17256 | 270 |
BNIP3,PMAIP1,BNIP3L,HK2 |
| 3.397e-02 | -3.38 | functioning | COSMIC cancer mutations | functioning | 1848 | 40 | 17385 | 281 |
CCDC148,ZHX3,DOCK1,ARHGEF11,CCDC110,PTPN21,CYP4V2,PLXNA2,KIF5C,ZNF219,HMCN1,TIAM2,MTUS1,TMEM53,MARVELD2,EHD3,EBF4,SRGAP1,PRICKLE2,DAB2IP,RAB27B,MOXD1,TLN2,DNAH5,GPR161,C3orf67,QSOX1,IL17RD,KLHL3,PTPN6,PPFIA4,WNT11,LHPP,NT5DC2,RERE,TCF7L1,IFT81,KIAA0355,HK2,KIAA0513 |
| 3.397e-02 | -3.38 | adrenal_gland-adrenal_gland-adrenal_cortical_carcinoma-functioning | COSMIC cancer mutations | adrenal_gland-adrenal_gland-adrenal_cortical_carcinoma-functioning | 1848 | 40 | 17385 | 281 |
CCDC148,ZHX3,DOCK1,ARHGEF11,CCDC110,PTPN21,CYP4V2,PLXNA2,KIF5C,ZNF219,HMCN1,TIAM2,MTUS1,TMEM53,MARVELD2,EHD3,EBF4,SRGAP1,PRICKLE2,DAB2IP,RAB27B,MOXD1,TLN2,DNAH5,GPR161,C3orf67,QSOX1,IL17RD,KLHL3,PTPN6,PPFIA4,WNT11,LHPP,NT5DC2,RERE,TCF7L1,IFT81,KIAA0355,HK2,KIAA0513 |
| 3.404e-02 | -3.38 | GSE29949_DC_BRAIN_VS_MONOCYTE_BONE_MARROW_UP | MSigDB lists | GSE29949_DC_BRAIN_VS_MONOCYTE_BONE_MARROW_UP | 188 | 7 | 17377 | 282 |
QSOX1,RGS16,ACVR1,ACSL1,ZHX3,SATB1,PKIA |
| 3.404e-02 | -3.38 | GSE1432_CTRL_VS_IFNG_6H_MICROGLIA_UP | MSigDB lists | GSE1432_CTRL_VS_IFNG_6H_MICROGLIA_UP | 188 | 7 | 17377 | 282 |
ARHGAP26,ACVR2B,ADAMTS3,STXBP1,TBC1D16,NT5DC2,MTUS1 |
| 3.404e-02 | -3.38 | GSE19825_NAIVE_VS_IL2RALOW_DAY3_EFF_CD8_TCELL_UP | MSigDB lists | GSE19825_NAIVE_VS_IL2RALOW_DAY3_EFF_CD8_TCELL_UP | 188 | 7 | 17377 | 282 |
EPCAM,C2orf88,ACVR1,TSHR,RNF122,BACE1,PGBD5 |
| 3.404e-02 | -3.38 | GSE2405_0H_VS_24H_A_PHAGOCYTOPHILUM_STIM_NEUTROPHIL_DN | MSigDB lists | GSE2405_0H_VS_24H_A_PHAGOCYTOPHILUM_STIM_NEUTROPHIL_DN | 188 | 7 | 17377 | 282 |
LONRF1,PPM1E,SHISA2,IFT81,IQSEC2,RNF157,PTPN21 |
| 3.404e-02 | -3.38 | GSE21670_STAT3_KO_VS_WT_CD4_TCELL_DN | MSigDB lists | GSE21670_STAT3_KO_VS_WT_CD4_TCELL_DN | 188 | 7 | 17377 | 282 |
PDK1,RAB27B,RNF157,SFXN4,DACT1,SLC39A8,MYC |
| 3.404e-02 | -3.38 | GSE38304_MYC_NEG_VS_POS_GC_BCELL_DN | MSigDB lists | GSE38304_MYC_NEG_VS_POS_GC_BCELL_DN | 188 | 7 | 17377 | 282 |
ARHGAP26,RUNX2,RNF157,ST14,RECK,GPR155,DSTN |
| 3.416e-02 | -3.38 | SH3 | prosite domains | PS50002 | 223 | 8 | 12060 | 202 |
ARHGAP26,FGR,DOCK1,MPP1,UBASH3B,SPATA13,SRGAP1,CACNB4 |
| 3.431e-02 | -3.37 | upper_aerodigestive_tract-head_neck-carcinoma-squamous_cell_carcinoma | COSMIC cancer mutations | upper_aerodigestive_tract-head_neck-carcinoma-squamous_cell_carcinoma | 9495 | 169 | 17385 | 281 |
ARHGAP26,ACVR1,DUSP8,LGR4,RECK,PTPN21,CEBPA,SLC2A13,ITPR2,ABAT,PRKCA,ABHD4,HMCN1,EPDR1,FKBP9,PPM1E,PMAIP1,DLX6,CFHR1,TMEM37,TLN2,OR2W3,TSHR,PNRC1,KLHL3,WISP3,CAPN5,BNIP3L,SLC25A28,TTC22,TNS1,PLEKHA1,ACVR2B,SGK2,SAV1,NT5DC2,PLEKHB1,DYRK1B,PLK2,RASGRF2,ERN1,ALDOA,MAPK13,TANC2,APBA2,TMEM63C,RGS16,SCN5A,RUNX2,SCART1,ZHX3,FBXO4,CYP4V2,SETBP1,RASL11B,TNFRSF10C,SATB1,FHOD3,MTUS1,IL17D,NUMBL,RALGPS2,MYC,EBF4,SRGAP1,BNIP3,VGLL4,GPR161,SPATA13,PPFIA4,WDR25,WWC1,STRADB,MAFB,PRDM1,LHPP,B4GALNT3,ADAMTS3,ISM1,LRRIQ3,EMILIN2,HK2,CLMN,IQSEC2,RNF122,SMYD3,ZNF516,RASAL2,ST14,DOCK1,FAM131C,PLXNA2,RHPN2,COLEC10,KIF21B,RADIL,TIAM2,RPS6KL1,DACT1,EEPD1,ZNF521,MAP7,MYH15,PJA1,PDE4D,RAB27B,DNAH5,HSPA2,KIAA1549,DZANK1,PHLDB2,GAPDH,PDK1,PTPN6,CYB5R2,ADCY1,NLGN4X,WNT11,RAB38,LMLN,ANKRD31,WFS1,WWTR1,PLEKHG1,P4HA1,TNFSF15,DISP1,KLHL31,COBL,MXI1,NECAB2,PRSS16,ARHGEF11,BIK,ARL2,GAS6,ZNF219,NEO1,RGS17,PRKCD,RASD2,EHD3,PRICKLE2,TRIM3,SGK1,B9D1,MN1,TMC7,PXN,MPP1,NUAK2,OGDHL,PALLD,TLR6,CTIF,GPLD1,TRIB3,FGR,FMO4,GNAO1,MAP2K6,KIAA0513,MYOM2,ZNF474,TNFRSF17,RNF157,DDIT3,B4GALT7,PHC1 |
| 3.432e-02 | -3.37 | large_intestine | COSMIC cancer mutations | large_intestine | 17068 | 280 | 17385 | 281 |
ARHGAP26,ACVR1,DUSP8,LGR4,RECK,LSM11,ALG1L,CEBPA,PRKCA,ABHD6,NCS1,EPDR1,PMAIP1,CFHR1,TMEM37,TSHR,TBC1D8,KLHL23,KLHL3,WISP3,EXOC6B,DSTN,BNIP3L,SLC25A28,ABCC2,TNS1,ACVR2B,SAV1,SPATA9,PLK2,RASGRF2,ALDOA,ARHGAP28,MAPK13,TMOD2,TANC2,SCN5A,TMEM63C,ZHX3,CYP2J2,SLC36A4,TNFRSF10C,DYNC1I1,HPCAL4,NIPSNAP3B,MTUS1,IL17D,RALGPS2,MYC,ZIC5,SRGAP1,MOXD1,STXBP1,GPR161,EPB41L5,BDNF,QSOX1,SHISA2,ARRDC4,OR11H4,ZNF558,ADAMTS3,ISM1,LRRIQ3,QPCTL,EMILIN2,CLMN,IQSEC2,SMYD3,ZNF516,RASAL2,ST14,C4A,FAM131C,CCDC110,PLXNA2,COLEC10,TIAM2,TMEM53,ZNF827,KMO,DACT1,DAB2IP,PJA1,PDE4D,RAB27B,DNAH5,ATP6AP1L,KIAA1549,C3orf67,DZANK1,GAPDH,PDK1,SOX21,CYB5R2,SFXN4,ADCY1,NLGN4X,SATB2,WNT11,RAB38,TBC1D16,TRIQK,IQCK,WFS1,WWTR1,PLEKHG1,P4HA1,TNFSF15,DBP,KLHL31,COBL,KCTD1,C2orf88,CCDC148,MXI1,TMEM132C,BACE1,BIK,CCNJL,KIF5C,ARL2,GAS6,ZNF219,NEO1,RGS17,GPR155,SMPDL3A,PARP9,TMC7,MN1,B9D1,SLC40A1,PXN,MPP1,GPR137C,GPLD1,TRIB3,FGR,GNAO1,MYOM2,TNFRSF17,DDIT3,B4GALT7,PHC1,CCDC126,ACSL1,HEBP1,PTPN21,NDRG2,NRN1,ABAT,ITPR2,SLC2A13,CACNB4,ABHD4,HMCN1,EPCAM,PPM1E,FKBP9,CPNE2,MARVELD2,DLX6,TMEM143,TLN2,FANK1,OR2W3,ZNF391,PGBD5,PNRC1,CAPN5,ATOX1,TTC22,PLEKHA1,SGK2,NT5DC2,PLEKHB1,DYRK1B,SPNS1,TCF7L1,ERN1,DLX2,APBA2,GPR63,LONRF1,RGS16,RUNX2,ZNF395,BVES,SCART1,FBXO4,UBASH3B,CYP4V2,ATP6V1E2,RASL11B,SETBP1,CHADL,SATB1,PFN2,FHOD3,NUMBL,SLC30A4,GAN,EBF4,BNIP3,NCEH1,VGLL4,BARX1,IL17RD,SPATA13,EFNA3,MAFB,STRADB,WWC1,WDR25,PPFIA4,LHPP,PRDM1,B4GALNT3,KIAA0355,HK2,RNF122,DOCK1,RHPN2,FAM198B,KIF21B,RADIL,CBLN1,KCTD15,RPS6KL1,ZDHHC23,EEPD1,ZNF521,MAP7,MYH15,TMEM120B,FAM78B,HSPA2,PHLDB2,UROS,SLC39A8,PTPN6,JAM3,CENPV,IFT81,LMLN,ANKRD31,RBPMS2,DISP1,NECAB2,PRSS16,ARHGEF11,BLVRB,SLX1B,OVOL2,PRKCD,RASD2,EHD3,GTF2F2,ACTA2,PRICKLE2,TRIM3,SGK1,CCDC122,KIAA0408,MSX1,NUAK2,OGDHL,EXOG,PALLD,TLR6,CTIF,RERE,FMO4,MAP2K6,KIAA0513,ZNF474,THAP10,RNF157,PKIA |
| 3.436e-02 | -3.37 | SCHAEFFER_SOX9_TARGETS_IN_PROSTATE_DEVELOPMENT_DN | MSigDB lists | SCHAEFFER_SOX9_TARGETS_IN_PROSTATE_DEVELOPMENT_DN | 44 | 3 | 17377 | 282 |
DAB2IP,COLEC10,ZNF521 |
| 3.436e-02 | -3.37 | ZHAN_MULTIPLE_MYELOMA_MS_UP | MSigDB lists | ZHAN_MULTIPLE_MYELOMA_MS_UP | 44 | 3 | 17377 | 282 |
PALLD,JAM3,ZNF521 |
| 3.436e-02 | -3.37 | V$HOX13_01 | MSigDB lists | V$HOX13_01 | 44 | 3 | 17377 | 282 |
COLEC10,GPR161,NEO1 |
| 3.436e-02 | -3.37 | SATO_SILENCED_BY_DEACETYLATION_IN_PANCREATIC_CANCER | MSigDB lists | SATO_SILENCED_BY_DEACETYLATION_IN_PANCREATIC_CANCER | 44 | 3 | 17377 | 282 |
CAPN5,BIK,PHC1 |
| 3.436e-02 | -3.37 | chr6q23 | MSigDB lists | chr6q23 | 44 | 3 | 17377 | 282 |
MAP7,SGK1,MOXD1 |
| 3.436e-02 | -3.37 | PID_DELTA_NP63_PATHWAY | MSigDB lists | PID_DELTA_NP63_PATHWAY | 44 | 3 | 17377 | 282 |
TCF7L1,RAB38,DLX6 |
| 3.436e-02 | -3.37 | MA_MYELOID_DIFFERENTIATION_DN | MSigDB lists | MA_MYELOID_DIFFERENTIATION_DN | 44 | 3 | 17377 | 282 |
APBA2,HSPA2,GNAO1 |
| 3.439e-02 | -3.37 | GAA (glucosidase alpha, acid) | protein interactions | 2548 | 43 | 3 | 17029 | 283 |
NUMBL,B4GALNT3,B4GALT7 |
| 3.439e-02 | -3.37 | MAP3K20 (mitogen-activated protein kinase kinase kinase 20) | protein interactions | 51776 | 43 | 3 | 17029 | 283 |
MAP2K6,MPP1,MYC |
| 3.445e-02 | -3.37 | negative regulation of molecular function | biological process | GO:0044092 | 1140 | 26 | 17256 | 270 |
EPB41L5,MSX1,MXI1,GAPDH,DUSP8,RECK,C4A,PTPN6,UBASH3B,ARL2,CEBPA,GAS6,TNFRSF10C,TRIB3,PPM1E,DACT1,CFHR1,WFS1,PRKCD,WWTR1,ARHGAP28,DAB2IP,SMYD3,PKIA,DDIT3,PARP9 |
| 3.448e-02 | -3.37 | V$HNF1_01 | MSigDB lists | V$HNF1_01 | 230 | 8 | 17377 | 282 |
ZNF827,BDNF,RALGPS2,GAN,EEPD1,TNS1,SATB2,SGK2 |
| 3.453e-02 | -3.37 | divalent metal ion transport | biological process | GO:0070838 | 283 | 9 | 17256 | 270 |
SLC40A1,SLC30A4,SLC39A8,ITPR2,TMEM37,GAS6,CACNB4,NCS1,DDIT3 |
| 3.455e-02 | -3.37 | SMID_BREAST_CANCER_BASAL_DN | MSigDB lists | SMID_BREAST_CANCER_BASAL_DN | 645 | 17 | 17377 | 282 |
B9D1,DZANK1,HEBP1,BLVRB,BIK,ADCY1,KIF5C,FAM198B,RAB38,ABAT,MTUS1,RALGPS2,KMO,TMEM143,TRIM3,RAB27B,HSPA2 |
| 3.455e-02 | -3.37 | Hippo signaling pathway | KEGG pathways | ko04390 | 154 | 6 | 7161 | 113 |
WWC1,TCF7L1,WNT11,SAV1,MYC,WWTR1 |
| 3.455e-02 | -3.37 | Hippo signaling pathway | KEGG pathways | hsa04390 | 154 | 6 | 7161 | 113 |
WWC1,TCF7L1,WNT11,SAV1,MYC,WWTR1 |
| 3.457e-02 | -3.36 | dendrite | cellular component | GO:0030425 | 579 | 15 | 18223 | 280 |
BDNF,NECAB2,PLK2,C4A,WFS1,GNAO1,NLGN4X,TRIM3,DAB2IP,BNIP3,KIF21B,OR11H4,APBA2,COBL,NCS1 |
| 3.459e-02 | -3.36 | regulation of osteoblast differentiation | biological process | GO:0045667 | 115 | 5 | 17256 | 270 |
CEBPA,RUNX2,ACVR2B,ACVR1,ZHX3 |
| 3.470e-02 | -3.36 | IKEDA_MIR30_TARGETS_UP | MSigDB lists | IKEDA_MIR30_TARGETS_UP | 111 | 5 | 17377 | 282 |
P4HA1,BDNF,ACVR1,SATB1,GNAO1 |
| 3.472e-02 | -3.36 | purine nucleotide binding | molecular function | GO:0017076 | 1854 | 40 | 17224 | 278 |
RUNX2,ACSL1,ACVR1,BVES,ARL2,KIF5C,RASL11B,KIF21B,PRKCA,RPS6KL1,PRKCD,RASD2,EHD3,GTF2F2,ACTA2,SGK1,MYH15,PDE4D,EPHB6,RAB27B,DNAH5,HSPA2,PDK1,NUAK2,ADCY1,STRADB,ABCC2,RAB38,ACVR2B,SGK2,GRK3,DYRK1B,TRIB3,FGR,PLK2,MAP2K6,GNAO1,ERN1,HK2,MAPK13 |
| 3.472e-02 | -3.36 | MAPKAP1 (mitogen-activated protein kinase associated protein 1) | protein interactions | 79109 | 74 | 4 | 17029 | 283 |
SGK1,PHLDB2,RASAL2,PRKCA |
| 3.472e-02 | -3.36 | NAF1 (nuclear assembly factor 1 ribonucleoprotein) | protein interactions | 92345 | 74 | 4 | 17029 | 283 |
EPB41L5,MPP1,NCS1,PTPN21 |
| 3.474e-02 | -3.36 | positive regulation of cellular biosynthetic process | biological process | GO:0031328 | 1801 | 38 | 17256 | 270 |
RUNX2,ZNF516,ACVR1,LGR4,ARHGEF11,FBXO4,CEBPA,OVOL2,ZNF219,KDM7A,EPCAM,MYC,PRKCD,GTF2F2,EBF4,DAB2IP,TSHR,FANK1,BARX1,GPR161,PARP9,SLC40A1,MSX1,SOX21,WWC1,MAFB,WNT11,SATB2,PXYLP1,TLR6,GPLD1,RERE,DYRK1B,WWTR1,DBP,DLX2,SMYD3,DDIT3 |
| 3.480e-02 | -3.36 | PDZ_sf | interpro domains | IPR036034 | 151 | 6 | 18492 | 296 |
RHPN2,ARHGEF11,APBA2,RADIL,MPP1,TIAM2 |
| 3.481e-02 | -3.36 | FIGUEROA_AML_METHYLATION_CLUSTER_3_UP | MSigDB lists | FIGUEROA_AML_METHYLATION_CLUSTER_3_UP | 149 | 6 | 17377 | 282 |
MAP7,TANC2,PMAIP1,PFN2,ZIC5,GAN |
| 3.481e-02 | -3.36 | GSE25123_WT_VS_PPARG_KO_MACROPHAGE_ROSIGLITAZONE_STIM_DN | MSigDB lists | GSE25123_WT_VS_PPARG_KO_MACROPHAGE_ROSIGLITAZONE_STIM_DN | 149 | 6 | 17377 | 282 |
SCN5A,MPP1,LSM11,SMYD3,KIAA1549,BNIP3L |
| 3.484e-02 | -3.36 | bladder | COSMIC cancer mutations | bladder | 14512 | 246 | 17385 | 281 |
ARHGAP26,CCDC126,ACSL1,ACVR1,DUSP8,LGR4,RECK,HEBP1,LSM11,PTPN21,ALG1L,NDRG2,NRN1,CEBPA,ITPR2,SLC2A13,PRKCA,CACNB4,ABHD6,ABHD4,HMCN1,EPDR1,EPCAM,CPNE2,FKBP9,PPM1E,PMAIP1,DLX6,MARVELD2,CFHR1,TMEM143,TMEM37,TLN2,OR2W3,TSHR,FANK1,TBC1D8,PGBD5,PNRC1,KLHL23,KLHL3,WISP3,CAPN5,BNIP3L,TTC22,ABCC2,TNS1,ACVR2B,PLEKHA1,SGK2,SAV1,NT5DC2,PLEKHB1,SPATA9,SPNS1,DYRK1B,TCF7L1,PLK2,RASGRF2,ERN1,ALDOA,ARHGAP28,MAPK13,TMOD2,DLX2,TANC2,APBA2,LONRF1,GPR63,SCN5A,RGS16,TMEM63C,RUNX2,ZNF395,ZHX3,BVES,CYP2J2,FBXO4,UBASH3B,CYP4V2,ATP6V1E2,SETBP1,RASL11B,SLC36A4,TNFRSF10C,SATB1,DYNC1I1,PFN2,HPCAL4,NIPSNAP3B,FHOD3,MTUS1,NUMBL,SLC30A4,RALGPS2,MYC,ZIC5,SRGAP1,BNIP3,NCEH1,MOXD1,VGLL4,STXBP1,BARX1,GPR161,EPB41L5,BDNF,QSOX1,EFNA3,SPATA13,PPFIA4,STRADB,MAFB,WWC1,PRDM1,LHPP,OR11H4,B4GALNT3,ZNF558,KIAA0355,ADAMTS3,ISM1,QPCTL,LRRIQ3,EMILIN2,HK2,CLMN,IQSEC2,RNF122,SMYD3,ZNF516,RASAL2,ST14,DOCK1,C4A,FAM131C,CCDC110,PLXNA2,RHPN2,FAM198B,KIF21B,COLEC10,RADIL,CBLN1,TIAM2,TMEM53,ZNF827,KCTD15,KMO,DACT1,RPS6KL1,ZDHHC23,EEPD1,ZNF521,MAP7,DAB2IP,MYH15,PDE4D,PJA1,RAB27B,DNAH5,TMEM120B,FAM78B,ATP6AP1L,HSPA2,C3orf67,DZANK1,PHLDB2,GAPDH,UROS,PDK1,SLC39A8,PTPN6,SFXN4,ADCY1,NLGN4X,WNT11,SATB2,RAB38,TBC1D16,JAM3,IFT81,LMLN,WFS1,RBPMS2,WWTR1,PLEKHG1,P4HA1,TNFSF15,DISP1,DBP,KLHL31,COBL,CCDC148,MXI1,NECAB2,PRSS16,ARHGEF11,BACE1,BIK,CCNJL,ARL2,KIF5C,GAS6,NEO1,RGS17,GPR155,PRKCD,RASD2,ACTA2,SGK1,PRICKLE2,CCDC122,TRIM3,SMPDL3A,PARP9,B9D1,TMC7,MN1,SLC40A1,PXN,MSX1,MPP1,NUAK2,OGDHL,EXOG,PALLD,GPR137C,TLR6,RERE,GPLD1,CTIF,TRIB3,FGR,FMO4,MAP2K6,GNAO1,KIAA0513,MYOM2,THAP10,TNFRSF17,RNF157,B4GALT7,DDIT3,PKIA,PHC1 |
| 3.484e-02 | -3.36 | urinary_tract | COSMIC cancer mutations | urinary_tract | 14512 | 246 | 17385 | 281 |
ARHGAP26,CCDC126,ACSL1,ACVR1,DUSP8,LGR4,RECK,HEBP1,LSM11,PTPN21,ALG1L,NDRG2,NRN1,CEBPA,SLC2A13,ITPR2,PRKCA,ABHD4,CACNB4,ABHD6,HMCN1,EPDR1,EPCAM,CPNE2,FKBP9,PPM1E,PMAIP1,DLX6,MARVELD2,CFHR1,TMEM143,TMEM37,TLN2,OR2W3,TSHR,FANK1,TBC1D8,PGBD5,PNRC1,KLHL23,KLHL3,WISP3,CAPN5,BNIP3L,TTC22,ABCC2,TNS1,PLEKHA1,ACVR2B,SGK2,SAV1,NT5DC2,PLEKHB1,SPNS1,DYRK1B,SPATA9,TCF7L1,PLK2,RASGRF2,ERN1,ALDOA,ARHGAP28,MAPK13,TMOD2,DLX2,TANC2,APBA2,LONRF1,GPR63,SCN5A,RGS16,TMEM63C,RUNX2,ZNF395,ZHX3,BVES,UBASH3B,CYP2J2,FBXO4,CYP4V2,SETBP1,RASL11B,ATP6V1E2,SLC36A4,TNFRSF10C,PFN2,SATB1,DYNC1I1,HPCAL4,NIPSNAP3B,FHOD3,MTUS1,NUMBL,RALGPS2,SLC30A4,MYC,ZIC5,SRGAP1,BNIP3,NCEH1,MOXD1,VGLL4,STXBP1,BARX1,GPR161,EPB41L5,BDNF,QSOX1,EFNA3,SPATA13,PPFIA4,WWC1,STRADB,MAFB,PRDM1,LHPP,OR11H4,B4GALNT3,ZNF558,ADAMTS3,KIAA0355,ISM1,LRRIQ3,QPCTL,EMILIN2,HK2,CLMN,IQSEC2,RNF122,SMYD3,ZNF516,RASAL2,DOCK1,ST14,C4A,FAM131C,CCDC110,PLXNA2,RHPN2,FAM198B,COLEC10,KIF21B,RADIL,CBLN1,TIAM2,TMEM53,ZNF827,KCTD15,KMO,RPS6KL1,DACT1,ZNF521,ZDHHC23,EEPD1,MAP7,DAB2IP,MYH15,PJA1,PDE4D,RAB27B,DNAH5,TMEM120B,FAM78B,ATP6AP1L,HSPA2,C3orf67,DZANK1,PHLDB2,GAPDH,UROS,PDK1,SLC39A8,PTPN6,SFXN4,ADCY1,NLGN4X,SATB2,WNT11,RAB38,TBC1D16,JAM3,IFT81,LMLN,WFS1,RBPMS2,WWTR1,PLEKHG1,P4HA1,TNFSF15,DISP1,DBP,KLHL31,COBL,CCDC148,MXI1,NECAB2,PRSS16,ARHGEF11,BACE1,BIK,CCNJL,KIF5C,ARL2,GAS6,NEO1,RGS17,GPR155,PRKCD,RASD2,ACTA2,CCDC122,TRIM3,PRICKLE2,SGK1,SMPDL3A,PARP9,TMC7,MN1,B9D1,SLC40A1,MSX1,PXN,MPP1,OGDHL,NUAK2,PALLD,EXOG,TLR6,GPR137C,RERE,GPLD1,CTIF,TRIB3,FGR,MAP2K6,GNAO1,FMO4,KIAA0513,MYOM2,TNFRSF17,THAP10,RNF157,PKIA,DDIT3,B4GALT7,PHC1 |
| 3.488e-02 | -3.36 | GSE17721_POLYIC_VS_CPG_6H_BMDC_UP | MSigDB lists | GSE17721_POLYIC_VS_CPG_6H_BMDC_UP | 189 | 7 | 17377 | 282 |
FGR,TMEM37,ACVR1,PNRC1,RASAL2,STXBP1,VGLL4 |
| 3.488e-02 | -3.36 | GSE23308_WT_VS_MINERALCORTICOID_REC_KO_MACROPHAGE_DN | MSigDB lists | GSE23308_WT_VS_MINERALCORTICOID_REC_KO_MACROPHAGE_DN | 189 | 7 | 17377 | 282 |
IL17RD,FGR,ACSL1,TLR6,RBPMS2,ERN1,PARP9 |
| 3.488e-02 | -3.36 | GSE24726_WT_VS_E2-2_KO_PDC_DN | MSigDB lists | GSE24726_WT_VS_E2-2_KO_PDC_DN | 189 | 7 | 17377 | 282 |
TANC2,DOCK1,UBASH3B,EMILIN2,PRKCD,ATOX1,PARP9 |
| 3.488e-02 | -3.36 | GSE26030_UNSTIM_VS_RESTIM_TH1_DAY5_POST_POLARIZATION_UP | MSigDB lists | GSE26030_UNSTIM_VS_RESTIM_TH1_DAY5_POST_POLARIZATION_UP | 189 | 7 | 17377 | 282 |
STRADB,SLC36A4,ABHD4,PFN2,MAP2K6,B4GALT7,SMPDL3A |
| 3.488e-02 | -3.36 | GSE4142_NAIVE_BCELL_VS_PLASMA_CELL_DN | MSigDB lists | GSE4142_NAIVE_BCELL_VS_PLASMA_CELL_DN | 189 | 7 | 17377 | 282 |
PPM1E,DAB2IP,RALGPS2,TANC2,ABHD4,SFXN4,CYB5R2 |
| 3.488e-02 | -3.36 | GSE34006_WT_VS_A2AR_KO_TREG_DN | MSigDB lists | GSE34006_WT_VS_A2AR_KO_TREG_DN | 189 | 7 | 17377 | 282 |
MAP7,SLC25A28,PDK1,CFHR1,GPR155,PKIA,PARP9 |
| 3.488e-02 | -3.36 | GSE7852_TREG_VS_TCONV_LN_UP | MSigDB lists | GSE7852_TREG_VS_TCONV_LN_UP | 189 | 7 | 17377 | 282 |
CCDC122,ZNF516,TANC2,MPP1,UBASH3B,HK2,ZDHHC23 |
| 3.488e-02 | -3.36 | GSE43955_TH0_VS_TGFB_IL6_TH17_ACT_CD4_TCELL_1H_DN | MSigDB lists | GSE43955_TH0_VS_TGFB_IL6_TH17_ACT_CD4_TCELL_1H_DN | 189 | 7 | 17377 | 282 |
MAP7,MAPK13,CEBPA,MSX1,SATB1,HEBP1,PHC1 |
| 3.488e-02 | -3.36 | GSE40666_NAIVE_VS_EFFECTOR_CD8_TCELL_UP | MSigDB lists | GSE40666_NAIVE_VS_EFFECTOR_CD8_TCELL_UP | 189 | 7 | 17377 | 282 |
IFT81,SLC30A4,RALGPS2,SATB1,PFN2,MAP2K6,PHC1 |
| 3.488e-02 | -3.36 | GSE7764_NKCELL_VS_SPLENOCYTE_UP | MSigDB lists | GSE7764_NKCELL_VS_SPLENOCYTE_UP | 189 | 7 | 17377 | 282 |
DAB2IP,TMEM37,RUNX2,RAB27B,RNF157,UBASH3B,GAN |
| 3.488e-02 | -3.36 | GSE21670_TGFB_VS_IL6_TREATED_STAT3_KO_CD4_TCELL_DN | MSigDB lists | GSE21670_TGFB_VS_IL6_TREATED_STAT3_KO_CD4_TCELL_DN | 189 | 7 | 17377 | 282 |
ARHGAP26,PRDM1,KIF21B,MAP2K6,HEBP1,RASGRF2,EHD3 |
| 3.488e-02 | -3.36 | GSE24142_ADULT_VS_FETAL_EARLY_THYMIC_PROGENITOR_UP | MSigDB lists | GSE24142_ADULT_VS_FETAL_EARLY_THYMIC_PROGENITOR_UP | 189 | 7 | 17377 | 282 |
IFT81,SLC30A4,SATB1,ABHD4,KMO,WFS1,CYP4V2 |
| 3.488e-02 | -3.36 | GSE26912_TUMORICIDAL_VS_CTRL_MACROPHAGE_UP | MSigDB lists | GSE26912_TUMORICIDAL_VS_CTRL_MACROPHAGE_UP | 189 | 7 | 17377 | 282 |
DAB2IP,RGS16,SCAMP1,SLC39A8,CAPN5,WWTR1,PLXNA2 |
| 3.488e-02 | -3.36 | GSE32423_MEMORY_VS_NAIVE_CD8_TCELL_UP | MSigDB lists | GSE32423_MEMORY_VS_NAIVE_CD8_TCELL_UP | 189 | 7 | 17377 | 282 |
KIF5C,CPNE2,PRDM1,LHPP,RUNX2,ST14,NUAK2 |
| 3.497e-02 | -3.35 | ribonucleotide binding | molecular function | GO:0032553 | 1855 | 40 | 17224 | 278 |
RUNX2,ACSL1,ACVR1,BVES,ARL2,KIF5C,RASL11B,KIF21B,PRKCA,RPS6KL1,PRKCD,RASD2,EHD3,GTF2F2,ACTA2,SGK1,MYH15,PDE4D,EPHB6,RAB27B,DNAH5,HSPA2,PDK1,NUAK2,ADCY1,STRADB,ABCC2,RAB38,ACVR2B,SGK2,GRK3,DYRK1B,TRIB3,FGR,PLK2,MAP2K6,GNAO1,ERN1,HK2,MAPK13 |
| 3.501e-02 | -3.35 | embryonic digestive tract morphogenesis | biological process | GO:0048557 | 19 | 2 | 17256 | 270 |
OVOL2,RBPMS2 |
| 3.501e-02 | -3.35 | positive regulation of chondrocyte differentiation | biological process | GO:0032332 | 19 | 2 | 17256 | 270 |
RUNX2,ZNF219 |
| 3.501e-02 | -3.35 | dendritic tree | cellular component | GO:0097447 | 580 | 15 | 18223 | 280 |
BDNF,NECAB2,PLK2,C4A,WFS1,GNAO1,NLGN4X,TRIM3,DAB2IP,BNIP3,KIF21B,OR11H4,APBA2,COBL,NCS1 |
| 3.507e-02 | -3.35 | GO_SOMITE_DEVELOPMENT | MSigDB lists | GO_SOMITE_DEVELOPMENT | 76 | 4 | 17377 | 282 |
EPB41L5,WNT11,COBL,PLXNA2 |
| 3.507e-02 | -3.35 | GO_MICROTUBULE_MOTOR_ACTIVITY | MSigDB lists | GO_MICROTUBULE_MOTOR_ACTIVITY | 76 | 4 | 17377 | 282 |
KIF5C,KIF21B,DYNC1I1,DNAH5 |
| 3.510e-02 | -3.35 | lung-carcinoma-undifferentiated_carcinoma | COSMIC cancer mutations | lung-carcinoma-undifferentiated_carcinoma | 1421 | 32 | 17385 | 281 |
ARHGAP26,ACVR1,RASL11B,PRKCA,RADIL,NUMBL,PMAIP1,MYC,PRKCD,RASD2,SGK1,TLN2,TSHR,PARP9,MN1,IL17RD,PXN,PDK1,PTPN6,MAFB,WNT11,ACVR2B,SAV1,SGK2,TLR6,TCF7L1,RASGRF2,GNAO1,MAP2K6,MAPK13,TNFRSF17,DDIT3 |
| 3.510e-02 | -3.35 | negative regulation of myeloid leukocyte differentiation | biological process | GO:0002762 | 46 | 3 | 17256 | 270 |
MAFB,MYC,UBASH3B |
| 3.524e-02 | -3.35 | GO_CELL_CORTEX | MSigDB lists | GO_CELL_CORTEX | 231 | 8 | 17377 | 282 |
PHLDB2,PXN,DSTN,MPP1,EXOC6B,ITPR2,HMCN1,COBL |
| 3.524e-02 | -3.35 | RRAGTTGT_UNKNOWN | MSigDB lists | RRAGTTGT_UNKNOWN | 231 | 8 | 17377 | 282 |
PRICKLE2,BDNF,ARHGEF11,HEBP1,JAM3,RERE,ZNF521,PLXNA2 |
| 3.524e-02 | -3.35 | HIRSCH_CELLULAR_TRANSFORMATION_SIGNATURE_UP | MSigDB lists | HIRSCH_CELLULAR_TRANSFORMATION_SIGNATURE_UP | 231 | 8 | 17377 | 282 |
RGS17,PNRC1,PMAIP1,SLC39A8,CYB5R2,P4HA1,BNIP3,MTUS1 |
| 3.524e-02 | -3.35 | V$ARNT_02 | MSigDB lists | V$ARNT_02 | 231 | 8 | 17377 | 282 |
SPNS1,BDNF,GAPDH,ADAMTS3,OGDHL,SGK1,TRIM3,DLX2 |
| 3.526e-02 | -3.35 | aromatic compound catabolic process | biological process | GO:0019439 | 472 | 13 | 17256 | 270 |
GAPDH,PNRC1,KMO,BLVRB,ERN1,ALDOA,OGDHL,HK2,PDE4D,EXOG,MOXD1,SMPDL3A,CTIF |
| 3.526e-02 | -3.35 | Fcgamma receptor (FCGR) dependent phagocytosis | REACTOME pathways | R-HSA-2029480 | 86 | 4 | 10287 | 148 |
FGR,ITPR2,DOCK1,PRKCD |
| 3.526e-02 | -3.35 | GO_VASCULATURE_DEVELOPMENT | MSigDB lists | GO_VASCULATURE_DEVELOPMENT | 455 | 13 | 17377 | 282 |
B9D1,ACVR1,RECK,ACTA2,DAB2IP,WNT11,PRDM1,ACVR2B,OVOL2,PRKCA,JAM3,DDIT3,GPLD1 |
| 3.527e-02 | -3.34 | G Protein Signaling Pathways | WikiPathways | WP35 | 96 | 5 | 5312 | 101 |
PDE4D,PRKCA,GNAO1,PRKCD,ADCY1 |
| 3.527e-02 | -3.34 | GO_NEGATIVE_REGULATION_OF_PROTEIN_MODIFICATION_PROCESS | MSigDB lists | GO_NEGATIVE_REGULATION_OF_PROTEIN_MODIFICATION_PROCESS | 598 | 16 | 17377 | 282 |
DUSP8,UBASH3B,PTPN6,NDRG2,CEBPA,PPM1E,TRIB3,MYC,DACT1,PRKCD,WWTR1,RASD2,DAB2IP,PDE4D,SMYD3,PKIA |
| 3.528e-02 | -3.34 | - | gene3d domains | 3.30.2320.30 | 2 | 1 | 8148 | 145 |
ATP6V1E2 |
| 3.528e-02 | -3.34 | - | gene3d domains | 4.10.770.10 | 2 | 1 | 8148 | 145 |
RUNX2 |
| 3.534e-02 | -3.34 | GRM1 (glutamate metabotropic receptor 1) | protein interactions | 2911 | 18 | 2 | 17029 | 283 |
GAPDH,PRKCA |
| 3.534e-02 | -3.34 | METTL3 (methyltransferase like 3) | protein interactions | 56339 | 18 | 2 | 17029 | 283 |
MPP1,MYC |
| 3.534e-02 | -3.34 | ZNF420 (zinc finger protein 420) | protein interactions | 147923 | 18 | 2 | 17029 | 283 |
SAV1,CYP4V2 |
| 3.534e-02 | -3.34 | HDHD2 (haloacid dehalogenase like hydrolase domain containing 2) | protein interactions | 84064 | 18 | 2 | 17029 | 283 |
LHPP,EPHB6 |
| 3.534e-02 | -3.34 | RRM2B (ribonucleotide reductase regulatory TP53 inducible subunit M2B) | protein interactions | 50484 | 18 | 2 | 17029 | 283 |
TMOD2,MYC |
| 3.534e-02 | -3.34 | PLEKHG6 (pleckstrin homology and RhoGEF domain containing G6) | protein interactions | 55200 | 18 | 2 | 17029 | 283 |
ACTA2,TMOD2 |
| 3.534e-02 | -3.34 | GPSM2 (G protein signaling modulator 2) | protein interactions | 29899 | 18 | 2 | 17029 | 283 |
GNAO1,LSM11 |
| 3.534e-02 | -3.34 | GCLM (glutamate-cysteine ligase modifier subunit) | protein interactions | 2730 | 18 | 2 | 17029 | 283 |
UROS,PRKCA |
| 3.534e-02 | -3.34 | myelodysplastic-myeloproliferative_neoplasm-unclassifiable | COSMIC cancer mutations | myelodysplastic-myeloproliferative_neoplasm-unclassifiable | 112 | 5 | 17385 | 281 |
ARHGAP26,SETBP1,MN1,CEBPA,MYC |
| 3.534e-02 | -3.34 | haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-myelodysplastic-myeloproliferative_neoplasm-unclassifiable | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-myelodysplastic-myeloproliferative_neoplasm-unclassifiable | 112 | 5 | 17385 | 281 |
ARHGAP26,SETBP1,MN1,CEBPA,MYC |
| 3.535e-02 | -3.34 | cellular response to carbohydrate stimulus | biological process | GO:0071322 | 79 | 4 | 17256 | 270 |
MAPK13,GAS6,MAP2K6,ERN1 |
| 3.535e-02 | -3.34 | somite development | biological process | GO:0061053 | 79 | 4 | 17256 | 270 |
EPB41L5,WNT11,COBL,PLXNA2 |
| 3.539e-02 | -3.34 | PTB | smart domains | SM00462 | 40 | 3 | 9493 | 172 |
TNS1,NUMBL,APBA2 |
| 3.552e-02 | -3.34 | anion binding | molecular function | GO:0043168 | 2747 | 56 | 17224 | 278 |
ARHGAP26,RUNX2,ACSL1,ACVR1,BVES,ARL2,KIF5C,RASL11B,ITPR2,GAS6,ABAT,KIF21B,PRKCA,PFN2,KMO,RPS6KL1,PRKCD,RASD2,EHD3,GTF2F2,ACTA2,SGK1,DAB2IP,MYH15,PDE4D,EPHB6,RAB27B,DNAH5,HSPA2,PARP9,PDK1,WISP3,CYB5R2,NUAK2,OGDHL,ADCY1,NLGN4X,STRADB,ABCC2,ACVR2B,PLEKHA1,RAB38,SGK2,GRK3,DYRK1B,TRIB3,FGR,ADAMTS3,PLK2,FMO4,MAP2K6,GNAO1,ERN1,HK2,P4HA1,MAPK13 |
| 3.570e-02 | -3.33 | determination of left/right symmetry | biological process | GO:0007368 | 116 | 5 | 17256 | 270 |
DISP1,ACVR2B,OVOL2,ACVR1,DNAH5 |
| 3.570e-02 | -3.33 | regulation of protein localization to nucleus | biological process | GO:1900180 | 116 | 5 | 17256 | 270 |
GAS6,FBXO4,PRKCD,PKIA,PARP9 |
| 3.573e-02 | -3.33 | GSE27670_CTRL_VS_LMP1_TRANSDUCED_GC_BCELL_DN | MSigDB lists | GSE27670_CTRL_VS_LMP1_TRANSDUCED_GC_BCELL_DN | 190 | 7 | 17377 | 282 |
MAFB,SPNS1,FKBP9,IFT81,TLR6,MPP1,MYC |
| 3.573e-02 | -3.33 | GSE9650_EFFECTOR_VS_MEMORY_CD8_TCELL_DN | MSigDB lists | GSE9650_EFFECTOR_VS_MEMORY_CD8_TCELL_DN | 190 | 7 | 17377 | 282 |
PLEKHA1,PDK1,PNRC1,SATB1,TLR6,MYC,RERE |
| 3.573e-02 | -3.33 | GSE41978_KLRG1_HIGH_VS_LOW_EFFECTOR_CD8_TCELL_UP | MSigDB lists | GSE41978_KLRG1_HIGH_VS_LOW_EFFECTOR_CD8_TCELL_UP | 190 | 7 | 17377 | 282 |
NDRG2,TMOD2,OVOL2,SAV1,KMO,JAM3,HK2 |
| 3.573e-02 | -3.33 | GSE40273_XBP1_KO_VS_WT_TREG_DN | MSigDB lists | GSE40273_XBP1_KO_VS_WT_TREG_DN | 190 | 7 | 17377 | 282 |
CCDC122,NDRG2,ITPR2,PRSS16,MAP2K6,EHD3,GAN |
| 3.573e-02 | -3.33 | GSE23505_IL6_IL1_IL23_VS_IL6_IL1_TGFB_TREATED_CD4_TCELL_UP | MSigDB lists | GSE23505_IL6_IL1_IL23_VS_IL6_IL1_TGFB_TREATED_CD4_TCELL_UP | 190 | 7 | 17377 | 282 |
ARL2,SLC40A1,MAPK13,LHPP,RASGRF2,BLVRB,BIK |
| 3.573e-02 | -3.33 | GSE17721_0.5H_VS_8H_LPS_BMDC_DN | MSigDB lists | GSE17721_0.5H_VS_8H_LPS_BMDC_DN | 190 | 7 | 17377 | 282 |
PHLDB2,SLC40A1,RUNX2,STXBP1,GPR155,JAM3,CAPN5 |
| 3.573e-02 | -3.33 | GSE36888_STAT5_AB_KNOCKIN_VS_WT_TCELL_IL2_TREATED_2H_DN | MSigDB lists | GSE36888_STAT5_AB_KNOCKIN_VS_WT_TCELL_IL2_TREATED_2H_DN | 190 | 7 | 17377 | 282 |
TRIM3,CLMN,RUNX2,ST14,KLHL23,BLVRB,BNIP3L |
| 3.573e-02 | -3.33 | GSE1791_CTRL_VS_NEUROMEDINU_IN_T_CELL_LINE_6H_UP | MSigDB lists | GSE1791_CTRL_VS_NEUROMEDINU_IN_T_CELL_LINE_6H_UP | 190 | 7 | 17377 | 282 |
DAB2IP,TRIB3,PJA1,PDK1,KLHL23,HK2,BNIP3L |
| 3.573e-02 | -3.33 | GSE40277_GATA1_AND_SATB1_TRANSDUCED_VS_CTRL_CD4_TCELL_DN | MSigDB lists | GSE40277_GATA1_AND_SATB1_TRANSDUCED_VS_CTRL_CD4_TCELL_DN | 190 | 7 | 17377 | 282 |
RASL11B,ZNF219,SATB1,RNF157,TMEM120B,CTIF,PHC1 |
| 3.573e-02 | -3.33 | GSE17721_CTRL_VS_CPG_0.5H_BMDC_UP | MSigDB lists | GSE17721_CTRL_VS_CPG_0.5H_BMDC_UP | 190 | 7 | 17377 | 282 |
QSOX1,TMOD2,PLEKHA1,PXN,SATB1,RECK,SOX21 |
| 3.573e-02 | -3.33 | GSE17721_CTRL_VS_CPG_1H_BMDC_DN | MSigDB lists | GSE17721_CTRL_VS_CPG_1H_BMDC_DN | 190 | 7 | 17377 | 282 |
ENAM,BDNF,SHISA2,IFT81,RAB27B,SFXN4,PLK2 |
| 3.573e-02 | -3.33 | GSE40441_NRP1_POS_INDUCED_TREG_VS_NRP1_NEG_NATURAL_TREG_UP | MSigDB lists | GSE40441_NRP1_POS_INDUCED_TREG_VS_NRP1_NEG_NATURAL_TREG_UP | 190 | 7 | 17377 | 282 |
WWC1,ARRDC4,ABHD4,CCDC110,ALDOA,CYP4V2,TMEM143 |
| 3.579e-02 | -3.33 | GAVIN_FOXP3_TARGETS_CLUSTER_P3 | MSigDB lists | GAVIN_FOXP3_TARGETS_CLUSTER_P3 | 150 | 6 | 17377 | 282 |
EPCAM,PRDM1,ST14,EHD3,BIK,NEO1 |
| 3.579e-02 | -3.33 | GSE21927_EL4_VS_MCA203_TUMOR_MONOCYTES_UP | MSigDB lists | GSE21927_EL4_VS_MCA203_TUMOR_MONOCYTES_UP | 150 | 6 | 17377 | 282 |
NDRG2,RGS16,PDE4D,CACNB4,CYP2J2,PTPN6 |
| 3.586e-02 | -3.33 | SCHAEFFER_PROSTATE_DEVELOPMENT_12HR_UP | MSigDB lists | SCHAEFFER_PROSTATE_DEVELOPMENT_12HR_UP | 112 | 5 | 17377 | 282 |
SETBP1,RASL11B,BNIP3,PMAIP1,SLC39A8 |
| 3.591e-02 | -3.33 | Gp_dh_N | smart domains | SM00846 | 2 | 1 | 9493 | 172 |
GAPDH |
| 3.599e-02 | -3.32 | soft_tissue-striated_muscle-rhabdomyosarcoma | COSMIC cancer mutations | soft_tissue-striated_muscle-rhabdomyosarcoma | 602 | 16 | 17385 | 281 |
ARHGAP26,SCN5A,ARHGEF11,CYP2J2,EFNA3,ARL2,NLGN4X,WNT11,SATB2,PRDM1,PLEKHA1,RADIL,PFN2,ADAMTS3,PRICKLE2,PARP9 |
| 3.601e-02 | -3.32 | V$TAL1ALPHAE47_01 | MSigDB lists | V$TAL1ALPHAE47_01 | 232 | 8 | 17377 | 282 |
NUMBL,SCN5A,ACVR1,WWC1,MAP7,TRIM3,RADIL,DDIT3 |
| 3.601e-02 | -3.32 | V$MYB_Q6 | MSigDB lists | V$MYB_Q6 | 232 | 8 | 17377 | 282 |
BDNF,ADAMTS3,DOCK1,DACT1,WFS1,ALDOA,PFN2,PHC1 |
| 3.611e-02 | -3.32 | TP53 Regulates Transcription of Genes Involved in Cytochrome C Release | REACTOME pathways | R-HSA-6803204 | 21 | 2 | 10287 | 148 |
PMAIP1,BNIP3L |
| 3.632e-02 | -3.32 | GO_REGULATION_OF_PROTEIN_SERINE_THREONINE_KINASE_ACTIVITY | MSigDB lists | GO_REGULATION_OF_PROTEIN_SERINE_THREONINE_KINASE_ACTIVITY | 457 | 13 | 17377 | 282 |
TRIB3,ACSL1,DUSP8,MAP2K6,PTPN6,PRKCD,ERN1,DAB2IP,CEBPA,TNFSF15,TLR6,HSPA2,PKIA |
| 3.638e-02 | -3.31 | GO_SCAFFOLD_PROTEIN_BINDING | MSigDB lists | GO_SCAFFOLD_PROTEIN_BINDING | 45 | 3 | 17377 | 282 |
NLGN4X,SCN5A,PDE4D |
| 3.638e-02 | -3.31 | GCM_AQP4 | MSigDB lists | GCM_AQP4 | 45 | 3 | 17377 | 282 |
IL17D,NDRG2,TMOD2 |
| 3.638e-02 | -3.31 | HANN_RESISTANCE_TO_BCL2_INHIBITOR_DN | MSigDB lists | HANN_RESISTANCE_TO_BCL2_INHIBITOR_DN | 45 | 3 | 17377 | 282 |
RHPN2,TRIB3,MSX1 |
| 3.638e-02 | -3.31 | chr14q22 | MSigDB lists | chr14q22 | 45 | 3 | 17377 | 282 |
GPR137C,HSPA2,DACT1 |
| 3.638e-02 | -3.31 | ROESSLER_LIVER_CANCER_METASTASIS_DN | MSigDB lists | ROESSLER_LIVER_CANCER_METASTASIS_DN | 45 | 3 | 17377 | 282 |
TBC1D16,WWTR1,MTUS1 |
| 3.638e-02 | -3.31 | BEGUM_TARGETS_OF_PAX3_FOXO1_FUSION_DN | MSigDB lists | BEGUM_TARGETS_OF_PAX3_FOXO1_FUSION_DN | 45 | 3 | 17377 | 282 |
MAFB,WNT11,MYC |
| 3.647e-02 | -3.31 | CIP2A (cell proliferation regulating inhibitor of protein phosphatase 2A) | protein interactions | 57650 | 44 | 3 | 17029 | 283 |
SLC30A4,MYC,GAN |
| 3.647e-02 | -3.31 | BATF3 (basic leucine zipper ATF-like transcription factor 3) | protein interactions | 55509 | 44 | 3 | 17029 | 283 |
CEBPA,DBP,DDIT3 |
| 3.654e-02 | -3.31 | GNF2_SPTA1 | MSigDB lists | GNF2_SPTA1 | 77 | 4 | 17377 | 282 |
MXI1,MPP1,BLVRB,BNIP3L |
| 3.657e-02 | -3.31 | phosphoric ester hydrolase activity | molecular function | GO:0042578 | 367 | 11 | 17224 | 278 |
PPM1E,DUSP8,UBASH3B,PTPN6,PTPN21,LHPP,PDE4D,PXYLP1,NT5DC2,SMPDL3A,GPLD1 |
| 3.659e-02 | -3.31 | IRS4 (insulin receptor substrate 4) | protein interactions | 8471 | 110 | 5 | 17029 | 283 |
P4HA1,SAV1,LGR4,PTPN6,MYC |
| 3.660e-02 | -3.31 | GSE17721_POLYIC_VS_GARDIQUIMOD_4H_BMDC_DN | MSigDB lists | GSE17721_POLYIC_VS_GARDIQUIMOD_4H_BMDC_DN | 191 | 7 | 17377 | 282 |
EPB41L5,RGS17,PRDM1,OVOL2,RNF157,TMEM120B,B4GALT7 |
| 3.660e-02 | -3.31 | GSE39916_B_CELL_SPLEEN_VS_PLASMA_CELL_BONE_MARROW_UP | MSigDB lists | GSE39916_B_CELL_SPLEEN_VS_PLASMA_CELL_BONE_MARROW_UP | 191 | 7 | 17377 | 282 |
RASL11B,NDRG2,TNS1,RALGPS2,BACE1,DDIT3,BNIP3L |
| 3.660e-02 | -3.31 | GSE23502_BM_VS_COLON_TUMOR_MYELOID_DERIVED_SUPPRESSOR_CELL_UP | MSigDB lists | GSE23502_BM_VS_COLON_TUMOR_MYELOID_DERIVED_SUPPRESSOR_CELL_UP | 191 | 7 | 17377 | 282 |
EPCAM,PRDM1,PLEKHA1,PRKCA,SCAMP1,UBASH3B,HK2 |
| 3.660e-02 | -3.31 | GSE369_SOCS3_KO_VS_WT_LIVER_POST_IL6_INJECTION_DN | MSigDB lists | GSE369_SOCS3_KO_VS_WT_LIVER_POST_IL6_INJECTION_DN | 191 | 7 | 17377 | 282 |
STRADB,PPM1E,RNF122,HSPA2,ZNF558,GPR155,BLVRB |
| 3.660e-02 | -3.31 | V$GR_01 | MSigDB lists | V$GR_01 | 191 | 7 | 17377 | 282 |
CCDC126,BDNF,PRDM1,DLX2,PXN,DSTN,RERE |
| 3.660e-02 | -3.31 | GSE37533_UNTREATED_VS_PIOGLIZATONE_TREATED_CD4_TCELL_PPARG1_AND_FOXP3_TRASDUCED_DN | MSigDB lists | GSE37533_UNTREATED_VS_PIOGLIZATONE_TREATED_CD4_TCELL_PPARG1_AND_FOXP3_TRASDUCED_DN | 191 | 7 | 17377 | 282 |
TRIM3,LHPP,ZNF516,PXN,ZNF395,BLVRB,RERE |
| 3.660e-02 | -3.31 | GSE17721_CTRL_VS_PAM3CSK4_1H_BMDC_DN | MSigDB lists | GSE17721_CTRL_VS_PAM3CSK4_1H_BMDC_DN | 191 | 7 | 17377 | 282 |
IL17RD,RUNX2,SCAMP1,PALLD,SRGAP1,TBC1D8,SPATA13 |
| 3.660e-02 | -3.31 | KAECH_DAY8_EFF_VS_MEMORY_CD8_TCELL_DN | MSigDB lists | KAECH_DAY8_EFF_VS_MEMORY_CD8_TCELL_DN | 191 | 7 | 17377 | 282 |
PLEKHA1,PDK1,PNRC1,SATB1,TLR6,MYC,RERE |
| 3.660e-02 | -3.31 | GSE22886_DAY0_VS_DAY1_MONOCYTE_IN_CULTURE_UP | MSigDB lists | GSE22886_DAY0_VS_DAY1_MONOCYTE_IN_CULTURE_UP | 191 | 7 | 17377 | 282 |
KIAA0513,CLMN,LHPP,MXI1,ZNF395,SATB1,RERE |
| 3.660e-02 | -3.31 | GSE7460_CTRL_VS_TGFB_TREATED_ACT_FOXP3_HET_TCONV_UP | MSigDB lists | GSE7460_CTRL_VS_TGFB_TREATED_ACT_FOXP3_HET_TCONV_UP | 191 | 7 | 17377 | 282 |
CHADL,LMLN,PRDM1,SLC30A4,EMILIN2,ALDOA,HK2 |
| 3.660e-02 | -3.31 | GSE11961_MEMORY_BCELL_DAY7_VS_PLASMA_CELL_DAY7_DN | MSigDB lists | GSE11961_MEMORY_BCELL_DAY7_VS_PLASMA_CELL_DAY7_DN | 191 | 7 | 17377 | 282 |
SHISA2,TNS1,ARRDC4,SATB1,RPS6KL1,WWTR1,SPATA13 |
| 3.660e-02 | -3.31 | GSE7831_UNSTIM_VS_CPG_STIM_PDC_1H_DN | MSigDB lists | GSE7831_UNSTIM_VS_CPG_STIM_PDC_1H_DN | 191 | 7 | 17377 | 282 |
MXI1,TMEM37,PJA1,SAV1,MYC,CAPN5,ZDHHC23 |
| 3.662e-02 | -3.31 | human chr2q32.2 | chromosome location | human chr2q32.2 | 24 | 2 | 26185 | 331 |
SLC40A1,C2orf88 |
| 3.665e-02 | -3.31 | SWEET_LUNG_CANCER_KRAS_DN | MSigDB lists | SWEET_LUNG_CANCER_KRAS_DN | 411 | 12 | 17377 | 282 |
BDNF,FKBP9,ACSL1,RECK,CFHR1,WWTR1,ACTA2,NDRG2,PLEKHA1,SATB1,NT5DC2,PKIA |
| 3.677e-02 | -3.30 | hematopoietic progenitor cell differentiation | biological process | GO:0002244 | 80 | 4 | 17256 | 270 |
HERC6,BVES,JAM3,PTPN6 |
| 3.677e-02 | -3.30 | positive regulation of exocytosis | biological process | GO:0045921 | 80 | 4 | 17256 | 270 |
FGR,RAB27B,STXBP1,NCS1 |
| 3.677e-02 | -3.30 | renal tubule development | biological process | GO:0061326 | 80 | 4 | 17256 | 270 |
WNT11,LGR4,KLHL3,MYC |
| 3.678e-02 | -3.30 | SNF5_DN.V1_DN | MSigDB lists | SNF5_DN.V1_DN | 151 | 6 | 17377 | 282 |
TMEM53,RGS16,MAPK13,SLC30A4,CACNB4,EFNA3 |
| 3.678e-02 | -3.30 | GO_REGULATION_OF_CYCLIC_NUCLEOTIDE_METABOLIC_PROCESS | MSigDB lists | GO_REGULATION_OF_CYCLIC_NUCLEOTIDE_METABOLIC_PROCESS | 151 | 6 | 17377 | 282 |
PDE4D,PRKCA,TSHR,WFS1,GPR161,ADCY1 |
| 3.678e-02 | -3.30 | SMIRNOV_RESPONSE_TO_IR_6HR_UP | MSigDB lists | SMIRNOV_RESPONSE_TO_IR_6HR_UP | 151 | 6 | 17377 | 282 |
ACTA2,RGS16,PMAIP1,PLK2,DDIT3,ADCY1 |
| 3.678e-02 | -3.30 | Neurotransmitter Release Cycle | REACTOME pathways | R-HSA-112310 | 51 | 3 | 10287 | 148 |
PPFIA4,ABAT,STXBP1 |
| 3.679e-02 | -3.30 | CONCANNON_APOPTOSIS_BY_EPOXOMICIN_UP | MSigDB lists | CONCANNON_APOPTOSIS_BY_EPOXOMICIN_UP | 233 | 8 | 17377 | 282 |
ACTA2,EPCAM,PALLD,DYNC1I1,PLK2,BLVRB,WWTR1,DDIT3 |
| 3.679e-02 | -3.30 | BOYLAN_MULTIPLE_MYELOMA_C_D_DN | MSigDB lists | BOYLAN_MULTIPLE_MYELOMA_C_D_DN | 233 | 8 | 17377 | 282 |
EPCAM,RUNX2,SCAMP1,RECK,RHPN2,PRDM1,TNFRSF17,TBC1D8 |
| 3.680e-02 | -3.30 | neuron projection morphogenesis | biological process | GO:0048812 | 475 | 13 | 17256 | 270 |
NUMBL,BDNF,PLXNA2,EFNA3,ADCY1,KIF5C,SGK1,DAB2IP,PRKCA,STXBP1,COBL,RERE,NEO1 |
| 3.690e-02 | -3.30 | cervix-carcinoma-squamous_cell_carcinoma | COSMIC cancer mutations | cervix-carcinoma-squamous_cell_carcinoma | 12126 | 210 | 17385 | 281 |
CCDC126,ACSL1,DUSP8,LGR4,RECK,PTPN21,ALG1L,NRN1,CEBPA,SLC2A13,ITPR2,PRKCA,CACNB4,HMCN1,EPDR1,FKBP9,PPM1E,MARVELD2,CFHR1,TMEM143,TMEM37,TLN2,OR2W3,TSHR,FANK1,TBC1D8,PGBD5,ZNF391,PNRC1,KLHL23,KLHL3,WISP3,EXOC6B,DSTN,SLC25A28,ABCC2,TNS1,PLEKHA1,ACVR2B,NT5DC2,SPNS1,DYRK1B,SPATA9,TCF7L1,RASGRF2,ERN1,ALDOA,ARHGAP28,MAPK13,TMOD2,DLX2,TANC2,APBA2,LONRF1,GPR63,SCN5A,TMEM63C,RUNX2,ZNF395,SCART1,ZHX3,BVES,UBASH3B,CYP2J2,FBXO4,CYP4V2,SETBP1,ATP6V1E2,CHADL,TNFRSF10C,SATB1,DYNC1I1,HPCAL4,NIPSNAP3B,FHOD3,MTUS1,NUMBL,RALGPS2,MYC,ZIC5,EBF4,SRGAP1,GAN,BNIP3,VGLL4,STXBP1,BARX1,GPR161,IL17RD,QSOX1,SPATA13,PPFIA4,WWC1,STRADB,MAFB,SHISA2,PRDM1,B4GALNT3,ZNF558,ADAMTS3,KIAA0355,LRRIQ3,QPCTL,EMILIN2,HK2,CLMN,IQSEC2,ZNF516,RASAL2,DOCK1,ST14,FAM131C,C4A,CCDC110,PLXNA2,RHPN2,FAM198B,COLEC10,KIF21B,RADIL,CBLN1,TIAM2,ZNF827,KCTD15,KMO,RPS6KL1,DACT1,ZNF521,ZDHHC23,MAP7,DAB2IP,MYH15,PJA1,DNAH5,TMEM120B,FAM78B,ATP6AP1L,HSPA2,C3orf67,DZANK1,PHLDB2,GAPDH,PDK1,SLC39A8,SOX21,CYB5R2,SFXN4,ADCY1,NLGN4X,SATB2,WNT11,TBC1D16,JAM3,CENPV,IFT81,LMLN,ANKRD31,WFS1,PLEKHG1,DISP1,KLHL31,KCTD1,CCDC148,MXI1,NECAB2,TMEM132C,ARHGEF11,BACE1,BIK,CCNJL,KIF5C,OVOL2,ZNF219,NEO1,RGS17,GPR155,PRKCD,RASD2,EHD3,GTF2F2,CCDC122,PRICKLE2,KIAA0408,SMPDL3A,PARP9,TMC7,MN1,B9D1,SLC40A1,MSX1,PXN,MPP1,OGDHL,NUAK2,EXOG,PALLD,GPR137C,RERE,GPLD1,CTIF,TRIB3,FGR,GNAO1,KIAA0513,MYOM2,ZNF474,RNF157,PKIA,B4GALT7,PHC1 |
| 3.705e-02 | -3.30 | GSE13522_WT_VS_IFNG_KO_SKING_T_CRUZI_Y_STRAIN_INF_UP | MSigDB lists | GSE13522_WT_VS_IFNG_KO_SKING_T_CRUZI_Y_STRAIN_INF_UP | 113 | 5 | 17377 | 282 |
RGS17,FAM198B,COLEC10,FAM78B,HPCAL4 |
| 3.705e-02 | -3.30 | ephrin receptor activity | molecular function | GO:0005003 | 19 | 2 | 17224 | 278 |
EPHB6,EFNA3 |
| 3.707e-02 | -3.29 | transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding | molecular function | GO:0001077 | 278 | 9 | 17224 | 278 |
RUNX2,SOX21,MYC,EBF4,MAFB,CEBPA,SATB2,DBP,DDIT3 |
| 3.707e-02 | -3.29 | regulation of chondrocyte differentiation | biological process | GO:0032330 | 47 | 3 | 17256 | 270 |
CHADL,RUNX2,ZNF219 |
| 3.707e-02 | -3.29 | negative regulation of fat cell differentiation | biological process | GO:0045599 | 47 | 3 | 17256 | 270 |
TRIB3,DDIT3,WWTR1 |
| 3.713e-02 | -3.29 | hydrolase activity, acting on ester bonds | molecular function | GO:0016788 | 754 | 19 | 17224 | 278 |
DUSP8,UBASH3B,PTPN6,PTPN21,NLGN4X,SLX1B,LHPP,PXYLP1,EXOG,ABHD4,ABHD6,NT5DC2,GPLD1,PPM1E,ERN1,PDE4D,NCEH1,SMPDL3A,PGBD5 |
| 3.715e-02 | -3.29 | bone-tibia-chondrosarcoma-peripheral | COSMIC cancer mutations | bone-tibia-chondrosarcoma-peripheral | 19 | 2 | 17385 | 281 |
NDRG2,PLXNA2 |
| 3.716e-02 | -3.29 | Transmission across Chemical Synapses | REACTOME pathways | R-HSA-112315 | 217 | 7 | 10287 | 148 |
PPFIA4,ABAT,PRKCA,CACNB4,STXBP1,RASGRF2,ADCY1 |
| 3.718e-02 | -3.29 | WW_dom_sf | interpro domains | IPR036020 | 46 | 3 | 18492 | 296 |
WWC1,SAV1,WWTR1 |
| 3.729e-02 | -3.29 | GO_DEVELOPMENTAL_GROWTH | MSigDB lists | GO_DEVELOPMENTAL_GROWTH | 321 | 10 | 17377 | 282 |
EPB41L5,BDNF,WWTR1,NLGN4X,WNT11,PDE4D,PLEKHA1,ACVR2B,APBA2,COBL |
| 3.737e-02 | -3.29 | anterior/posterior pattern specification | biological process | GO:0009952 | 199 | 7 | 17256 | 270 |
EPB41L5,MSX1,ACVR2B,BARX1,COBL,DDIT3,PLXNA2 |
| 3.741e-02 | -3.29 | GO_REGULATION_OF_CELL_DEATH | MSigDB lists | GO_REGULATION_OF_CELL_DEATH | 1423 | 32 | 17377 | 282 |
ACVR1,ARHGEF11,BIK,GAS6,TNFRSF10C,PRKCA,TIAM2,EPCAM,PMAIP1,MYC,PRKCD,SGK1,BNIP3,DAB2IP,STXBP1,SLC40A1,BDNF,MSX1,WISP3,BNIP3L,NUAK2,STRADB,WNT11,SGK2,SAV1,GPLD1,RASGRF2,PLK2,WFS1,MAP2K6,TNFSF15,DDIT3 |
| 3.742e-02 | -3.29 | cellular response to chemical stimulus | biological process | GO:0070887 | 2786 | 55 | 17256 | 270 |
SCN5A,RUNX2,ACVR1,ACSL1,CYP2J2,ATP6V1E2,CEBPA,ITPR2,GAS6,TNFRSF10C,CPNE2,NUMBL,PPM1E,PMAIP1,KMO,MYC,PRKCD,GTF2F2,DAB2IP,BNIP3,PDE4D,NCEH1,TSHR,STXBP1,HSPA2,EPB41L5,BDNF,IL17RD,SLC40A1,MSX1,GAPDH,PXN,PDK1,UROS,PTPN6,ADCY1,BNIP3L,SATB2,GAREM1,ABCC2,WNT11,PLEKHA1,ACVR2B,TLR6,GPLD1,TRIB3,MAP2K6,WFS1,ERN1,HK2,TNFSF15,MAPK13,TNFRSF17,SMYD3,DDIT3 |
| 3.742e-02 | -3.29 | ZIRN_TRETINOIN_RESPONSE_UP | MSigDB lists | ZIRN_TRETINOIN_RESPONSE_UP | 19 | 2 | 17377 | 282 |
IQCK,PLK2 |
| 3.742e-02 | -3.29 | GO_CELLULAR_SODIUM_ION_HOMEOSTASIS | MSigDB lists | GO_CELLULAR_SODIUM_ION_HOMEOSTASIS | 19 | 2 | 17377 | 282 |
SGK1,SGK2 |
| 3.742e-02 | -3.29 | KIM_MYCL1_AMPLIFICATION_TARGETS_DN | MSigDB lists | KIM_MYCL1_AMPLIFICATION_TARGETS_DN | 19 | 2 | 17377 | 282 |
RHPN2,FKBP9 |
| 3.742e-02 | -3.29 | GO_EPHRIN_RECEPTOR_ACTIVITY | MSigDB lists | GO_EPHRIN_RECEPTOR_ACTIVITY | 19 | 2 | 17377 | 282 |
EPHB6,EFNA3 |
| 3.742e-02 | -3.29 | GO_TRANSFERASE_ACTIVITY_TRANSFERRING_NITROGENOUS_GROUPS | MSigDB lists | GO_TRANSFERASE_ACTIVITY_TRANSFERRING_NITROGENOUS_GROUPS | 19 | 2 | 17377 | 282 |
GAPDH,ABAT |
| 3.742e-02 | -3.29 | MODULE_156 | MSigDB lists | MODULE_156 | 19 | 2 | 17377 | 282 |
PLEKHA1,NCS1 |
| 3.742e-02 | -3.29 | GO_REGULATION_OF_RECEPTOR_RECYCLING | MSigDB lists | GO_REGULATION_OF_RECEPTOR_RECYCLING | 19 | 2 | 17377 | 282 |
TBC1D16,BVES |
| 3.742e-02 | -3.29 | GO_FIBRIL_ORGANIZATION | MSigDB lists | GO_FIBRIL_ORGANIZATION | 19 | 2 | 17377 | 282 |
ADAMTS3,B4GALT7 |
| 3.745e-02 | -3.28 | GO_EMBRYONIC_ORGAN_MORPHOGENESIS | MSigDB lists | GO_EMBRYONIC_ORGAN_MORPHOGENESIS | 277 | 9 | 17377 | 282 |
MSX1,ACVR1,RUNX2,DLX6,MAFB,WNT11,SATB2,OVOL2,DLX2 |
| 3.748e-02 | -3.28 | GSE17186_CD21LOW_VS_CD21HIGH_TRANSITIONAL_BCELL_DN | MSigDB lists | GSE17186_CD21LOW_VS_CD21HIGH_TRANSITIONAL_BCELL_DN | 192 | 7 | 17377 | 282 |
TNS1,ZNF516,ACSL1,ABHD6,GPR155,NUAK2,EEPD1 |
| 3.748e-02 | -3.28 | GSE37533_PPARG1_FOXP3_VS_FOXP3_TRANSDUCED_CD4_TCELL_PIOGLITAZONE_TREATED_UP | MSigDB lists | GSE37533_PPARG1_FOXP3_VS_FOXP3_TRANSDUCED_CD4_TCELL_PIOGLITAZONE_TREATED_UP | 192 | 7 | 17377 | 282 |
SCN5A,SLC25A28,MSX1,HERC6,SCAMP1,CYP2J2,HK2 |
| 3.748e-02 | -3.28 | GOLDRATH_EFF_VS_MEMORY_CD8_TCELL_DN | MSigDB lists | GOLDRATH_EFF_VS_MEMORY_CD8_TCELL_DN | 192 | 7 | 17377 | 282 |
DBP,ITPR2,PLEKHA1,PDK1,DDIT3,RERE,CYP4V2 |
| 3.748e-02 | -3.28 | HALLMARK_HEME_METABOLISM | MSigDB lists | HALLMARK_HEME_METABOLISM | 192 | 7 | 17377 | 282 |
TNS1,MXI1,UROS,HEBP1,MPP1,BLVRB,BNIP3L |
| 3.748e-02 | -3.28 | GSE8685_IL2_STARVED_VS_IL2_ACT_IL2_STARVED_CD4_TCELL_DN | MSigDB lists | GSE8685_IL2_STARVED_VS_IL2_ACT_IL2_STARVED_CD4_TCELL_DN | 192 | 7 | 17377 | 282 |
PHLDB2,CPNE2,RNF157,DOCK1,KIAA1549,NEO1,EEPD1 |
| 3.748e-02 | -3.28 | CHANG_CORE_SERUM_RESPONSE_DN | MSigDB lists | CHANG_CORE_SERUM_RESPONSE_DN | 192 | 7 | 17377 | 282 |
SLC40A1,MXI1,FAM198B,PNRC1,ZNF219,SATB1,IGIP |
| 3.748e-02 | -3.28 | GSE17721_LPS_VS_GARDIQUIMOD_6H_BMDC_UP | MSigDB lists | GSE17721_LPS_VS_GARDIQUIMOD_6H_BMDC_UP | 192 | 7 | 17377 | 282 |
FKBP9,MXI1,PNRC1,STXBP1,PLK2,PTPN6,FHOD3 |
| 3.748e-02 | -3.28 | GSE360_HIGH_DOSE_B_MALAYI_VS_M_TUBERCULOSIS_MAC_UP | MSigDB lists | GSE360_HIGH_DOSE_B_MALAYI_VS_M_TUBERCULOSIS_MAC_UP | 192 | 7 | 17377 | 282 |
NDRG2,FGR,PRKCA,ST14,VGLL4,FMO4,BLVRB |
| 3.748e-02 | -3.28 | GO_ANTERIOR_POSTERIOR_PATTERN_SPECIFICATION | MSigDB lists | GO_ANTERIOR_POSTERIOR_PATTERN_SPECIFICATION | 192 | 7 | 17377 | 282 |
EPB41L5,MSX1,ACVR2B,BARX1,COBL,DDIT3,PLXNA2 |
| 3.748e-02 | -3.28 | GSE17580_TREG_VS_TEFF_S_MANSONI_INF_UP | MSigDB lists | GSE17580_TREG_VS_TEFF_S_MANSONI_INF_UP | 192 | 7 | 17377 | 282 |
B9D1,EPCAM,PRDM1,SCAMP1,ARRDC4,ST14,CAPN5 |
| 3.758e-02 | -3.28 | V$IPF1_Q4 | MSigDB lists | V$IPF1_Q4 | 234 | 8 | 17377 | 282 |
ZNF827,BDNF,ZHX3,DOCK1,PLXNA2,EPHB6,PRDM1,NEO1 |
| 3.758e-02 | -3.28 | V$HMGIY_Q6 | MSigDB lists | V$HMGIY_Q6 | 234 | 8 | 17377 | 282 |
NDRG2,MSX1,KCTD15,PDE4D,RASAL2,SCAMP1,VGLL4,MAP2K6 |
| 3.758e-02 | -3.28 | cervix | COSMIC cancer mutations | cervix | 12130 | 210 | 17385 | 281 |
CCDC126,ACSL1,DUSP8,LGR4,RECK,PTPN21,ALG1L,NRN1,CEBPA,SLC2A13,ITPR2,PRKCA,CACNB4,HMCN1,EPDR1,FKBP9,PPM1E,MARVELD2,CFHR1,TMEM143,TMEM37,TLN2,OR2W3,TSHR,FANK1,TBC1D8,PGBD5,ZNF391,PNRC1,KLHL23,KLHL3,WISP3,EXOC6B,DSTN,SLC25A28,ABCC2,TNS1,PLEKHA1,ACVR2B,NT5DC2,SPNS1,DYRK1B,SPATA9,TCF7L1,RASGRF2,ERN1,ALDOA,ARHGAP28,MAPK13,TMOD2,DLX2,TANC2,APBA2,LONRF1,GPR63,SCN5A,TMEM63C,RUNX2,ZNF395,SCART1,ZHX3,BVES,UBASH3B,CYP2J2,FBXO4,CYP4V2,SETBP1,ATP6V1E2,CHADL,TNFRSF10C,SATB1,DYNC1I1,HPCAL4,NIPSNAP3B,FHOD3,MTUS1,NUMBL,RALGPS2,MYC,ZIC5,EBF4,SRGAP1,GAN,BNIP3,VGLL4,STXBP1,BARX1,GPR161,IL17RD,QSOX1,SPATA13,PPFIA4,WWC1,STRADB,MAFB,SHISA2,PRDM1,B4GALNT3,ZNF558,ADAMTS3,KIAA0355,LRRIQ3,QPCTL,EMILIN2,HK2,CLMN,IQSEC2,ZNF516,RASAL2,DOCK1,ST14,FAM131C,C4A,CCDC110,PLXNA2,RHPN2,FAM198B,COLEC10,KIF21B,RADIL,CBLN1,TIAM2,ZNF827,KCTD15,KMO,RPS6KL1,DACT1,ZNF521,ZDHHC23,MAP7,DAB2IP,MYH15,PJA1,DNAH5,TMEM120B,FAM78B,ATP6AP1L,HSPA2,C3orf67,DZANK1,PHLDB2,GAPDH,PDK1,SLC39A8,SOX21,CYB5R2,SFXN4,ADCY1,NLGN4X,SATB2,WNT11,TBC1D16,JAM3,CENPV,IFT81,LMLN,ANKRD31,WFS1,PLEKHG1,DISP1,KLHL31,KCTD1,CCDC148,MXI1,NECAB2,TMEM132C,ARHGEF11,BACE1,BIK,CCNJL,KIF5C,OVOL2,ZNF219,NEO1,RGS17,GPR155,PRKCD,RASD2,EHD3,GTF2F2,CCDC122,PRICKLE2,KIAA0408,SMPDL3A,PARP9,TMC7,MN1,B9D1,SLC40A1,MSX1,PXN,MPP1,OGDHL,NUAK2,EXOG,PALLD,GPR137C,RERE,GPLD1,CTIF,TRIB3,FGR,GNAO1,KIAA0513,MYOM2,ZNF474,RNF157,PKIA,B4GALT7,PHC1 |
| 3.766e-02 | -3.28 | GO_REGULATION_OF_PROTEIN_MODIFICATION_PROCESS | MSigDB lists | GO_REGULATION_OF_PROTEIN_MODIFICATION_PROCESS | 1638 | 36 | 17377 | 282 |
ACVR1,ACSL1,DUSP8,FBXO4,UBASH3B,NDRG2,CEBPA,GAS6,PRKCA,PFN2,PPM1E,DACT1,MYC,RASD2,PRKCD,DAB2IP,PDE4D,HSPA2,PTPN6,ADCY1,STRADB,WWC1,WNT11,ACVR2B,ARRDC4,TLR6,GPLD1,TRIB3,FGR,WFS1,MAP2K6,WWTR1,ERN1,TNFSF15,SMYD3,PKIA |
| 3.775e-02 | -3.28 | DDIT3 (DNA damage inducible transcript 3) | protein interactions | 1649 | 76 | 4 | 17029 | 283 |
TRIB3,CEBPA,DBP,DDIT3 |
| 3.779e-02 | -3.28 | GSE6259_FLT3L_INDUCED_VS_WT_SPLENIC_DC_33D1_POS_DN | MSigDB lists | GSE6259_FLT3L_INDUCED_VS_WT_SPLENIC_DC_33D1_POS_DN | 152 | 6 | 17377 | 282 |
MAFB,SLC40A1,PRKCA,PALLD,NEO1,PLXNA2 |
| 3.779e-02 | -3.28 | GO_CALCIUM_ION_TRANSMEMBRANE_TRANSPORT | MSigDB lists | GO_CALCIUM_ION_TRANSMEMBRANE_TRANSPORT | 152 | 6 | 17377 | 282 |
ITPR2,GAS6,TMEM37,CACNB4,NCS1,DDIT3 |
| 3.779e-02 | -3.28 | GACTGTT,MIR-212,MIR-132 | MSigDB lists | GACTGTT,MIR-212,MIR-132 | 152 | 6 | 17377 | 282 |
PRICKLE2,TCF7L1,PXN,ARHGEF11,PFN2,LSM11 |
| 3.779e-02 | -3.28 | GTTRYCATRR_UNKNOWN | MSigDB lists | GTTRYCATRR_UNKNOWN | 152 | 6 | 17377 | 282 |
PPM1E,GAPDH,THAP10,TBC1D16,HPCAL4,PHC1 |
| 3.780e-02 | -3.28 | MARTENS_BOUND_BY_PML_RARA_FUSION | MSigDB lists | MARTENS_BOUND_BY_PML_RARA_FUSION | 413 | 12 | 17377 | 282 |
MN1,FGR,ACSL1,PXN,UBASH3B,PTPN6,PRKCD,NUAK2,TMEM143,MAFB,ITPR2,RNF122 |
| 3.794e-02 | -3.27 | regulation of cell death | biological process | GO:0010941 | 1701 | 36 | 17256 | 270 |
ACVR1,ARHGEF11,BIK,GAS6,TNFRSF10C,PRKCA,TIAM2,PMAIP1,KMO,MYC,PRKCD,SGK1,DAB2IP,BNIP3,EPHB6,STXBP1,FANK1,BDNF,SLC40A1,GAPDH,MSX1,WISP3,NUAK2,BNIP3L,STRADB,WNT11,SAV1,SGK2,TLR6,GPLD1,MAP2K6,WFS1,RASGRF2,PLK2,TNFSF15,DDIT3 |
| 3.794e-02 | -3.27 | large_intestine-colon | COSMIC cancer mutations | large_intestine-colon | 1324 | 30 | 17385 | 281 |
MN1,PRSS16,RASAL2,DOCK1,PTPN6,CYB5R2,HEBP1,ATP6V1E2,ABAT,KIF21B,RADIL,TBC1D16,ABHD6,HMCN1,FHOD3,GPLD1,PLK2,ZNF521,KIAA0513,DAB2IP,ZNF474,DBP,TMEM37,IQSEC2,TLN2,DNAH5,FANK1,OR2W3,COBL,HSPA2 |
| 3.795e-02 | -3.27 | VECCHI_GASTRIC_CANCER_EARLY_DN | MSigDB lists | VECCHI_GASTRIC_CANCER_EARLY_DN | 322 | 10 | 17377 | 282 |
GPR155,GNAO1,RBPMS2,SETBP1,KIF5C,BNIP3,SLC36A4,ABAT,ARRDC4,TNFRSF17 |
| 3.796e-02 | -3.27 | GO_REGULATION_OF_CYTOPLASMIC_TRANSPORT | MSigDB lists | GO_REGULATION_OF_CYTOPLASMIC_TRANSPORT | 460 | 13 | 17377 | 282 |
MXI1,DACT1,UBASH3B,PTPN6,PRKCD,WWTR1,BNIP3L,DAB2IP,PDE4D,GAS6,STXBP1,PFN2,PKIA |
| 3.804e-02 | -3.27 | DUAN_PRDM5_TARGETS | MSigDB lists | DUAN_PRDM5_TARGETS | 78 | 4 | 17377 | 282 |
MYOM2,RUNX2,MYC,PHC1 |
| 3.804e-02 | -3.27 | GO_RENAL_TUBULE_DEVELOPMENT | MSigDB lists | GO_RENAL_TUBULE_DEVELOPMENT | 78 | 4 | 17377 | 282 |
WNT11,LGR4,KLHL3,MYC |
| 3.809e-02 | -3.27 | Response to antipsychotic treatment(PMID:20195266) | GWAS genes | Response to antipsychotic treatment(PMID:20195266) | 13 | 2 | 2388 | 58 |
CLMN,FHOD3 |
| 3.809e-02 | -3.27 | undifferentiated_carcinoma | COSMIC cancer mutations | undifferentiated_carcinoma | 1431 | 32 | 17385 | 281 |
ARHGAP26,ACVR1,RASL11B,PRKCA,RADIL,NUMBL,PMAIP1,MYC,PRKCD,RASD2,SGK1,TLN2,TSHR,PARP9,MN1,IL17RD,PXN,PDK1,PTPN6,MAFB,WNT11,ACVR2B,SAV1,SGK2,TLR6,TCF7L1,RASGRF2,GNAO1,MAP2K6,MAPK13,TNFRSF17,DDIT3 |
| 3.822e-02 | -3.26 | transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding | molecular function | GO:0000982 | 416 | 12 | 17224 | 278 |
RUNX2,MSX1,SOX21,MYC,EBF4,MAFB,CEBPA,SATB2,PRDM1,DBP,ZNF219,DDIT3 |
| 3.822e-02 | -3.26 | multicellular organism growth | biological process | GO:0035264 | 81 | 4 | 17256 | 270 |
PLEKHA1,PDE4D,APBA2,WWTR1 |
| 3.822e-02 | -3.26 | negative regulation of response to wounding | biological process | GO:1903035 | 81 | 4 | 17256 | 270 |
PHLDB2,ABAT,UBASH3B,PRKCD |
| 3.822e-02 | -3.26 | Hemostasis | REACTOME pathways | R-HSA-109582 | 632 | 15 | 10287 | 148 |
EPCAM,QSOX1,FGR,DOCK1,PTPN6,EHD3,ALDOA,PRKCD,GAS6,ITPR2,KIF21B,PRKCA,RAB27B,ABHD6,JAM3 |
| 3.825e-02 | -3.26 | inorganic ion transmembrane transport | biological process | GO:0098660 | 627 | 16 | 17256 | 270 |
SLC40A1,SCN5A,SLC30A4,SLC9C1,SLC39A8,ATOX1,ATP6V1E2,SLC25A28,ITPR2,GAS6,TMEM37,SLC2A13,CACNB4,ATP6AP1L,NCS1,DDIT3 |
| 3.825e-02 | -3.26 | GO_NEGATIVE_REGULATION_OF_CYTOPLASMIC_TRANSPORT | MSigDB lists | GO_NEGATIVE_REGULATION_OF_CYTOPLASMIC_TRANSPORT | 114 | 5 | 17377 | 282 |
DAB2IP,MXI1,GAS6,WWTR1,PKIA |
| 3.825e-02 | -3.26 | GO_SPECIFICATION_OF_SYMMETRY | MSigDB lists | GO_SPECIFICATION_OF_SYMMETRY | 114 | 5 | 17377 | 282 |
DISP1,ACVR2B,ACVR1,OVOL2,DNAH5 |
| 3.827e-02 | -3.26 | pulmonary_blastoma | COSMIC cancer mutations | pulmonary_blastoma | 656 | 17 | 17385 | 281 |
TMEM63C,KLHL23,PLXNA2,PPFIA4,WWC1,MAFB,SATB2,TBC1D16,DYNC1I1,FHOD3,CPNE2,FMO4,MARVELD2,LRRIQ3,MAP7,TLN2,TANC2 |
| 3.827e-02 | -3.26 | pleura-pulmonary_blastoma | COSMIC cancer mutations | pleura-pulmonary_blastoma | 656 | 17 | 17385 | 281 |
TMEM63C,KLHL23,PLXNA2,PPFIA4,WWC1,MAFB,SATB2,TBC1D16,DYNC1I1,FHOD3,CPNE2,FMO4,MARVELD2,LRRIQ3,MAP7,TLN2,TANC2 |
| 3.831e-02 | -3.26 | regulation of cellular component movement | biological process | GO:0051270 | 991 | 23 | 17256 | 270 |
EPB41L5,SCN5A,PHLDB2,ACVR1,DOCK1,RECK,MPP1,SPATA13,PLXNA2,WNT11,GAS6,PRKCA,PFN2,ABHD6,JAM3,MTUS1,GPLD1,FGR,PLK2,SRGAP1,SGK1,DAB2IP,PDE4D |
| 3.838e-02 | -3.26 | GSE7831_UNSTIM_VS_INFLUENZA_STIM_PDC_1H_DN | MSigDB lists | GSE7831_UNSTIM_VS_INFLUENZA_STIM_PDC_1H_DN | 193 | 7 | 17377 | 282 |
SHISA2,TANC2,SAV1,SCAMP1,PFN2,RASGRF2,CYP4V2 |
| 3.838e-02 | -3.26 | GSE20366_CD103_POS_VS_CD103_KLRG1_DP_TREG_DN | MSigDB lists | GSE20366_CD103_POS_VS_CD103_KLRG1_DP_TREG_DN | 193 | 7 | 17377 | 282 |
EPCAM,OVOL2,TMEM37,ZHX3,TBC1D16,COBL,ERN1 |
| 3.838e-02 | -3.26 | GSE24142_DN2_VS_DN3_THYMOCYTE_DN | MSigDB lists | GSE24142_DN2_VS_DN3_THYMOCYTE_DN | 193 | 7 | 17377 | 282 |
EPCAM,ITPR2,SATB1,TMEM120B,PFN2,RPS6KL1,TBC1D8 |
| 3.838e-02 | -3.26 | GSE7460_TCONV_VS_TREG_THYMUS_UP | MSigDB lists | GSE7460_TCONV_VS_TREG_THYMUS_UP | 193 | 7 | 17377 | 282 |
SGK1,QSOX1,ZHX3,ARHGEF11,SATB1,TLR6,PTPN6 |
| 3.838e-02 | -3.26 | GSE16522_ANTI_CD3CD28_STIM_VS_UNSTIM_MEMORY_CD8_TCELL_UP | MSigDB lists | GSE16522_ANTI_CD3CD28_STIM_VS_UNSTIM_MEMORY_CD8_TCELL_UP | 193 | 7 | 17377 | 282 |
KIAA0513,RASL11B,TNS1,WNT11,RUNX2,WFS1,NCS1 |
| 3.838e-02 | -3.26 | GSE360_T_GONDII_VS_B_MALAYI_LOW_DOSE_MAC_DN | MSigDB lists | GSE360_T_GONDII_VS_B_MALAYI_LOW_DOSE_MAC_DN | 193 | 7 | 17377 | 282 |
GAS6,ACVR1,IQSEC2,DOCK1,PRKCD,ATOX1,RERE |
| 3.838e-02 | -3.26 | GSE36527_CD62L_HIGH_CD69_NEG_VS_CD62L_LOW_CD69_POS_TREG_KLRG1_NEG_DN | MSigDB lists | GSE36527_CD62L_HIGH_CD69_NEG_VS_CD62L_LOW_CD69_POS_TREG_KLRG1_NEG_DN | 193 | 7 | 17377 | 282 |
PRDM1,PJA1,RASAL2,MOXD1,JAM3,MARVELD2,PARP9 |
| 3.847e-02 | -3.26 | GGGATGC,MIR-324-5P | MSigDB lists | GGGATGC,MIR-324-5P | 46 | 3 | 17377 | 282 |
RUNX2,ZHX3,GAN |
| 3.847e-02 | -3.26 | MCCLUNG_DELTA_FOSB_TARGETS_2WK | MSigDB lists | MCCLUNG_DELTA_FOSB_TARGETS_2WK | 46 | 3 | 17377 | 282 |
BDNF,APBA2,FHOD3 |
| 3.847e-02 | -3.26 | GO_COMPLEMENT_ACTIVATION | MSigDB lists | GO_COMPLEMENT_ACTIVATION | 46 | 3 | 17377 | 282 |
COLEC10,CFHR1,C4A |
| 3.847e-02 | -3.26 | chr6q25 | MSigDB lists | chr6q25 | 46 | 3 | 17377 | 282 |
RGS17,TIAM2,PLEKHG1 |
| 3.847e-02 | -3.26 | GO_POSITIVE_REGULATION_OF_ACTIN_FILAMENT_BUNDLE_ASSEMBLY | MSigDB lists | GO_POSITIVE_REGULATION_OF_ACTIN_FILAMENT_BUNDLE_ASSEMBLY | 46 | 3 | 17377 | 282 |
PPM1E,WNT11,PFN2 |
| 3.851e-02 | -3.26 | signal transduction involved in regulation of gene expression | biological process | GO:0023019 | 20 | 2 | 17256 | 270 |
EPCAM,MSX1 |
| 3.851e-02 | -3.26 | positive regulation of signal transduction by p53 class mediator | biological process | GO:1901798 | 20 | 2 | 17256 | 270 |
MSX1,PMAIP1 |
| 3.853e-02 | -3.26 | FERM_M | pfam domains | PF00373 | 47 | 3 | 17054 | 271 |
EPB41L5,TLN2,PTPN21 |
| 3.857e-02 | -3.26 | CREIGHTON_ENDOCRINE_THERAPY_RESISTANCE_3 | MSigDB lists | CREIGHTON_ENDOCRINE_THERAPY_RESISTANCE_3 | 654 | 17 | 17377 | 282 |
ARHGAP26,QSOX1,BDNF,LGR4,ST14,CAPN5,SLC2A13,PRKCA,CENPV,MTUS1,RGS17,RBPMS2,EEPD1,CLMN,TNFSF15,NCEH1,TBC1D8 |
| 3.861e-02 | -3.25 | NME2P1 (NME/NM23 nucleoside diphosphate kinase 2 pseudogene 1) | protein interactions | 283458 | 45 | 3 | 17029 | 283 |
TMEM53,PDK1,DUSP8 |
| 3.861e-02 | -3.25 | MYOC (myocilin) | protein interactions | 4653 | 45 | 3 | 17029 | 283 |
ACTA2,GAPDH,ALDOA |
| 3.868e-02 | -3.25 | endometrium-carcinoma-endometrioid_carcinoma | COSMIC cancer mutations | endometrium-carcinoma-endometrioid_carcinoma | 16168 | 269 | 17385 | 281 |
ARHGAP26,ACVR1,DUSP8,LGR4,RECK,LSM11,PRKCA,ABHD6,EPDR1,CFHR1,TMEM37,TSHR,TBC1D8,KLHL23,KLHL3,WISP3,EXOC6B,DSTN,BNIP3L,SLC25A28,ABCC2,TNS1,ACVR2B,SAV1,SPATA9,PLK2,RASGRF2,ALDOA,ARHGAP28,MAPK13,TMOD2,TANC2,SCN5A,TMEM63C,ZHX3,CYP2J2,SLC36A4,TNFRSF10C,DYNC1I1,HPCAL4,NIPSNAP3B,MTUS1,IL17D,RALGPS2,MYC,ZIC5,SRGAP1,MOXD1,STXBP1,GPR161,EPB41L5,BDNF,QSOX1,SHISA2,ARRDC4,OR11H4,ZNF558,ADAMTS3,ISM1,LRRIQ3,QPCTL,EMILIN2,CLMN,IQSEC2,SMYD3,ZNF516,RASAL2,ST14,FAM131C,CCDC110,PLXNA2,COLEC10,TIAM2,TMEM53,ZNF827,KMO,DACT1,DAB2IP,PJA1,PDE4D,RAB27B,DNAH5,ATP6AP1L,C3orf67,DZANK1,GAPDH,PDK1,SOX21,CYB5R2,SFXN4,ADCY1,NLGN4X,SATB2,WNT11,RAB38,TBC1D16,TRIQK,IQCK,WFS1,WWTR1,PLEKHG1,P4HA1,TNFSF15,DBP,KLHL31,COBL,KCTD1,CCDC148,MXI1,TMEM132C,BACE1,BIK,CCNJL,KIF5C,ARL2,ZNF219,NEO1,RGS17,GPR155,SMPDL3A,PARP9,TMC7,MN1,B9D1,SLC40A1,PXN,MPP1,GPR137C,GPLD1,TRIB3,FGR,GNAO1,MYOM2,TNFRSF17,DDIT3,B4GALT7,PHC1,CCDC126,ACSL1,HEBP1,PTPN21,NDRG2,NRN1,ABAT,ITPR2,SLC2A13,CACNB4,ABHD4,HMCN1,EPCAM,PPM1E,FKBP9,CPNE2,MARVELD2,DLX6,TMEM143,TLN2,FANK1,OR2W3,ZNF391,PGBD5,PNRC1,CAPN5,ATOX1,TTC22,PLEKHA1,SGK2,NT5DC2,PLEKHB1,DYRK1B,SPNS1,TCF7L1,ERN1,DLX2,APBA2,GPR63,LONRF1,RGS16,RUNX2,ZNF395,BVES,FBXO4,UBASH3B,CYP4V2,ATP6V1E2,SETBP1,CHADL,SATB1,PFN2,FHOD3,NUMBL,SLC30A4,GAN,EBF4,BNIP3,NCEH1,VGLL4,BARX1,IL17RD,SPATA13,EFNA3,MAFB,STRADB,WWC1,WDR25,PPFIA4,LHPP,PRDM1,B4GALNT3,KIAA0355,HK2,RNF122,DOCK1,RHPN2,FAM198B,KIF21B,RADIL,CBLN1,KCTD15,RPS6KL1,ZDHHC23,EEPD1,ZNF521,MAP7,MYH15,TMEM120B,HSPA2,FAM78B,PHLDB2,UROS,PTPN6,SLC39A8,JAM3,CENPV,IFT81,LMLN,ANKRD31,RBPMS2,DISP1,NECAB2,PRSS16,ARHGEF11,BLVRB,OVOL2,PRKCD,RASD2,EHD3,GTF2F2,ACTA2,PRICKLE2,TRIM3,SGK1,CCDC122,KIAA0408,MSX1,NUAK2,OGDHL,EXOG,PALLD,TLR6,CTIF,RERE,FMO4,MAP2K6,KIAA0513,ZNF474,THAP10,RNF157,PKIA |
| 3.881e-02 | -3.25 | mitochondrion | cellular component | GO:0005739 | 1564 | 33 | 18223 | 280 |
ACSL1,BIK,ARL2,ABAT,PRKCA,ABHD6,NIPSNAP3B,MTUS1,PPM1E,PMAIP1,KMO,TMEM143,SGK1,BNIP3,STXBP1,PARP9,BDNF,SMIM20,UROS,PDK1,SFXN4,CYB5R2,OGDHL,BNIP3L,SLC25A28,RAB38,EXOG,SPNS1,FGR,ERN1,HK2,P4HA1,MYOM2 |
| 3.882e-02 | -3.25 | GSE6674_UNSTIM_VS_CPG_STIM_BCELL_DN | MSigDB lists | GSE6674_UNSTIM_VS_CPG_STIM_BCELL_DN | 153 | 6 | 17377 | 282 |
QSOX1,LGR4,ABHD4,SFXN4,BACE1,TMEM143 |
| 3.882e-02 | -3.25 | GSE27241_CTRL_VS_DIGOXIN_TREATED_CD4_TCELL_IN_TH17_POLARIZING_CONDITIONS_UP | MSigDB lists | GSE27241_CTRL_VS_DIGOXIN_TREATED_CD4_TCELL_IN_TH17_POLARIZING_CONDITIONS_UP | 153 | 6 | 17377 | 282 |
MYOM2,RASAL2,KIF21B,ST14,PLK2,PTPN6 |
| 3.882e-02 | -3.25 | GSE40274_CTRL_VS_HELIOS_TRANSDUCED_ACTIVATED_CD4_TCELL_UP | MSigDB lists | GSE40274_CTRL_VS_HELIOS_TRANSDUCED_ACTIVATED_CD4_TCELL_UP | 153 | 6 | 17377 | 282 |
DAB2IP,CEBPA,KIF21B,KMO,PTPN6,GPR155 |
| 3.893e-02 | -3.25 | plasma membrane bounded cell projection morphogenesis | biological process | GO:0120039 | 479 | 13 | 17256 | 270 |
NUMBL,BDNF,PLXNA2,EFNA3,ADCY1,KIF5C,SGK1,DAB2IP,PRKCA,STXBP1,COBL,RERE,NEO1 |
| 3.897e-02 | -3.24 | BMP signaling | KEGG pathways | M00679 | 20 | 2 | 7161 | 113 |
ACVR2B,ACVR1 |
| 3.897e-02 | -3.24 | BMP signaling | KEGG pathways | hsa_M00679 | 20 | 2 | 7161 | 113 |
ACVR2B,ACVR1 |
| 3.899e-02 | -3.24 | DAGPEDOMAIN | prints domains | PR00008 | 21 | 2 | 4652 | 70 |
PRKCA,PRKCD |
| 3.907e-02 | -3.24 | BERENJENO_TRANSFORMED_BY_RHOA_DN | MSigDB lists | BERENJENO_TRANSFORMED_BY_RHOA_DN | 369 | 11 | 17377 | 282 |
FKBP9,IFT81,TCF7L1,RECK,HEBP1,CYP4V2,GAS6,ITPR2,TLR6,HSPA2,DDIT3 |
| 3.907e-02 | -3.24 | ISCU (iron-sulfur cluster assembly enzyme) | protein interactions | 23479 | 19 | 2 | 17029 | 283 |
LONRF1,NECAB2 |
| 3.907e-02 | -3.24 | SAMD4B (sterile alpha motif domain containing 4B) | protein interactions | 55095 | 19 | 2 | 17029 | 283 |
ACTA2,PTPN6 |
| 3.907e-02 | -3.24 | FOXF1 (forkhead box F1) | protein interactions | 2294 | 19 | 2 | 17029 | 283 |
SATB2,SATB1 |
| 3.907e-02 | -3.24 | NUBP1 (nucleotide binding protein 1) | protein interactions | 4682 | 19 | 2 | 17029 | 283 |
FKBP9,HK2 |
| 3.907e-02 | -3.24 | CYTH1 (cytohesin 1) | protein interactions | 9267 | 19 | 2 | 17029 | 283 |
INAVA,PRKCD |
| 3.907e-02 | -3.24 | SELE (selectin E) | protein interactions | 6401 | 19 | 2 | 17029 | 283 |
ACTA2,PXN |
| 3.907e-02 | -3.24 | KRT79 (keratin 79) | protein interactions | 338785 | 19 | 2 | 17029 | 283 |
LGR4,UBASH3B |
| 3.907e-02 | -3.24 | DLX5 (distal-less homeobox 5) | protein interactions | 1749 | 19 | 2 | 17029 | 283 |
MSX1,DLX2 |
| 3.908e-02 | -3.24 | GO_RESPONSE_TO_INORGANIC_SUBSTANCE | MSigDB lists | GO_RESPONSE_TO_INORGANIC_SUBSTANCE | 462 | 13 | 17377 | 282 |
CPNE2,SCN5A,SLC40A1,SLC30A4,GNAO1,PRKCD,ADCY1,BNIP3,CEBPA,PLEKHA1,ABAT,DDIT3,GPLD1 |
| 3.910e-02 | -3.24 | negative regulation of hemostasis | biological process | GO:1900047 | 48 | 3 | 17256 | 270 |
ABAT,UBASH3B,PRKCD |
| 3.910e-02 | -3.24 | positive regulation of epithelial to mesenchymal transition | biological process | GO:0010718 | 48 | 3 | 17256 | 270 |
EPB41L5,ACVR1,WWTR1 |
| 3.910e-02 | -3.24 | negative regulation of blood coagulation | biological process | GO:0030195 | 48 | 3 | 17256 | 270 |
ABAT,UBASH3B,PRKCD |
| 3.911e-02 | -3.24 | mesenchyme development | biological process | GO:0060485 | 201 | 7 | 17256 | 270 |
ACTA2,EPB41L5,WNT11,MSX1,OVOL2,ACVR1,WWTR1 |
| 3.928e-02 | -3.24 | GSE17721_LPS_VS_POLYIC_2H_BMDC_UP | MSigDB lists | GSE17721_LPS_VS_POLYIC_2H_BMDC_UP | 194 | 7 | 17377 | 282 |
FKBP9,RAB38,ACSL1,PALLD,TLR6,GPR155,CENPV |
| 3.928e-02 | -3.24 | GSE39820_TGFBETA1_IL6_VS_TGFBETA1_IL6_IL23A_TREATED_CD4_TCELL_UP | MSigDB lists | GSE39820_TGFBETA1_IL6_VS_TGFBETA1_IL6_IL23A_TREATED_CD4_TCELL_UP | 194 | 7 | 17377 | 282 |
P4HA1,SGK1,ACVR1,PXN,SLC39A8,UBASH3B,PHC1 |
| 3.928e-02 | -3.24 | GSE42021_TCONV_PLN_VS_TREG_PRECURSORS_THYMUS_DN | MSigDB lists | GSE42021_TCONV_PLN_VS_TREG_PRECURSORS_THYMUS_DN | 194 | 7 | 17377 | 282 |
PLEKHA1,ACSL1,SLC30A4,SCAMP1,MYC,HK2,SPATA13 |
| 3.928e-02 | -3.24 | GSE26488_WT_VS_HDAC7_DELTAP_TG_OT2_THYMOCYTE_WITH_PEPTIDE_INJECTION_DN | MSigDB lists | GSE26488_WT_VS_HDAC7_DELTAP_TG_OT2_THYMOCYTE_WITH_PEPTIDE_INJECTION_DN | 194 | 7 | 17377 | 282 |
RHPN2,QSOX1,ACVR1,GAS6,RALGPS2,SLC39A8,PLK2 |
| 3.928e-02 | -3.24 | HALLMARK_KRAS_SIGNALING_UP | MSigDB lists | HALLMARK_KRAS_SIGNALING_UP | 194 | 7 | 17377 | 282 |
MAP7,KIF5C,MAFB,RGS16,PRDM1,SATB1,FBXO4 |
| 3.928e-02 | -3.24 | GSE20715_0H_VS_48H_OZONE_TLR4_KO_LUNG_UP | MSigDB lists | GSE20715_0H_VS_48H_OZONE_TLR4_KO_LUNG_UP | 194 | 7 | 17377 | 282 |
TRIB3,ACVR2B,FAM198B,DBP,GAS6,RALGPS2,MAP2K6 |
| 3.932e-02 | -3.24 | FOXS1 (forkhead box S1) | protein interactions | 2307 | 77 | 4 | 17029 | 283 |
P4HA1,SATB2,SATB1,BARX1 |
| 3.932e-02 | -3.24 | PDPK1 (3-phosphoinositide dependent protein kinase 1) | protein interactions | 5170 | 77 | 4 | 17029 | 283 |
SGK1,PXN,SGK2,PRKCD |
| 3.935e-02 | -3.24 | Initial triggering of complement | REACTOME pathways | R-HSA-166663 | 22 | 2 | 10287 | 148 |
COLEC10,C4A |
| 3.935e-02 | -3.24 | SHC1 events in ERBB2 signaling | REACTOME pathways | R-HSA-1250196 | 22 | 2 | 10287 | 148 |
PRKCA,PRKCD |
| 3.938e-02 | -3.23 | heme degradation | BIOCYC pathways | HUMAN_PWY-5874 | 4 | 1 | 902 | 9 |
BLVRB |
| 3.938e-02 | -3.23 | sucrose degradation V (sucrose alpha-glucosidase) | BIOCYC pathways | META_PWY66-373 | 4 | 1 | 902 | 9 |
ALDOA |
| 3.938e-02 | -3.23 | arachidonate biosynthesis III (6-desaturase, mammals) | BIOCYC pathways | META_PWY-7592 | 4 | 1 | 902 | 9 |
ACSL1 |
| 3.939e-02 | -3.23 | ion transmembrane transport | biological process | GO:0034220 | 888 | 21 | 17256 | 270 |
SLC40A1,SCN5A,TMEM63C,SLC9C1,SLC39A8,SFXN4,ATOX1,ATP6V1E2,SLC36A4,SLC25A28,ITPR2,GAS6,SLC2A13,SGK2,CACNB4,NCS1,SLC30A4,SGK1,TMEM37,ATP6AP1L,DDIT3 |
| 3.944e-02 | -3.23 | glioma | COSMIC cancer mutations | glioma | 16557 | 274 | 17385 | 281 |
ARHGAP26,ACVR1,DUSP8,LGR4,RECK,LSM11,ALG1L,CEBPA,PRKCA,ABHD6,NCS1,EPDR1,PMAIP1,CFHR1,TMEM37,TSHR,TBC1D8,KLHL23,KLHL3,WISP3,EXOC6B,DSTN,BNIP3L,SLC25A28,ABCC2,TNS1,ACVR2B,SAV1,SPATA9,PLK2,RASGRF2,ALDOA,ARHGAP28,MAPK13,TMOD2,TANC2,SCN5A,ZHX3,CYP2J2,SLC36A4,TNFRSF10C,DYNC1I1,HPCAL4,NIPSNAP3B,MTUS1,IL17D,RALGPS2,MYC,ZIC5,SRGAP1,MOXD1,STXBP1,GPR161,EPB41L5,BDNF,QSOX1,SHISA2,ARRDC4,OR11H4,ZNF558,ADAMTS3,ISM1,LRRIQ3,QPCTL,EMILIN2,CLMN,IQSEC2,SMYD3,ZNF516,RASAL2,ST14,FAM131C,CCDC110,PLXNA2,COLEC10,TIAM2,TMEM53,ZNF827,KMO,DACT1,DAB2IP,PJA1,PDE4D,RAB27B,DNAH5,ATP6AP1L,KIAA1549,C3orf67,GAPDH,PDK1,SOX21,CYB5R2,SFXN4,ADCY1,NLGN4X,SATB2,WNT11,RAB38,TBC1D16,IQCK,WFS1,WWTR1,PLEKHG1,P4HA1,TNFSF15,DBP,KLHL31,COBL,KCTD1,C2orf88,CCDC148,MXI1,TMEM132C,BACE1,BIK,CCNJL,KIF5C,ARL2,GAS6,ZNF219,NEO1,RGS17,GPR155,SMPDL3A,PARP9,TMC7,MN1,B9D1,SLC40A1,PXN,MPP1,GPR137C,GPLD1,TRIB3,FGR,GNAO1,MYOM2,TNFRSF17,DDIT3,B4GALT7,PHC1,CCDC126,ACSL1,HEBP1,PTPN21,NDRG2,NRN1,ABAT,ITPR2,SLC2A13,CACNB4,ABHD4,HMCN1,EPCAM,PPM1E,FKBP9,CPNE2,MARVELD2,DLX6,TMEM143,TLN2,FANK1,OR2W3,ZNF391,PGBD5,PNRC1,CAPN5,ATOX1,TTC22,PLEKHA1,SGK2,NT5DC2,PLEKHB1,DYRK1B,SPNS1,TCF7L1,ERN1,DLX2,APBA2,GPR63,LONRF1,RGS16,RUNX2,ZNF395,BVES,FBXO4,UBASH3B,CYP4V2,ATP6V1E2,RASL11B,SETBP1,CHADL,SATB1,PFN2,FHOD3,NUMBL,SLC30A4,GAN,EBF4,BNIP3,NCEH1,VGLL4,BARX1,IL17RD,SPATA13,EFNA3,MAFB,STRADB,WWC1,WDR25,PPFIA4,LHPP,PRDM1,B4GALNT3,KIAA0355,HK2,RNF122,DOCK1,RHPN2,FAM198B,KIF21B,RADIL,CBLN1,KCTD15,RPS6KL1,ZDHHC23,EEPD1,ZNF521,MAP7,MYH15,TMEM120B,HSPA2,FAM78B,PHLDB2,UROS,SLC39A8,PTPN6,JAM3,CENPV,IFT81,LMLN,ANKRD31,RBPMS2,DISP1,NECAB2,PRSS16,ARHGEF11,BLVRB,OVOL2,PRKCD,RASD2,EHD3,GTF2F2,ACTA2,PRICKLE2,TRIM3,SGK1,CCDC122,KIAA0408,MSX1,NUAK2,OGDHL,EXOG,PALLD,TLR6,CTIF,RERE,FMO4,MAP2K6,KIAA0513,ZNF474,THAP10,RNF157,PKIA |
| 3.947e-02 | -3.23 | human chr1p12 | chromosome location | human chr1p12 | 25 | 2 | 26185 | 331 |
ZNF697,TENT5C |
| 3.948e-02 | -3.23 | GSE6259_FLT3L_INDUCED_DEC205_POS_DC_VS_CD4_TCELL_DN | MSigDB lists | GSE6259_FLT3L_INDUCED_DEC205_POS_DC_VS_CD4_TCELL_DN | 115 | 5 | 17377 | 282 |
STXBP1,ZIC5,CENPV,BIK,TMEM143 |
| 3.958e-02 | -3.23 | KEGG_FC_EPSILON_RI_SIGNALING_PATHWAY | MSigDB lists | KEGG_FC_EPSILON_RI_SIGNALING_PATHWAY | 79 | 4 | 17377 | 282 |
MAPK13,PRKCA,MAP2K6,PRKCD |
| 3.960e-02 | -3.23 | TIG | pfam domains | PF01833 | 20 | 2 | 17054 | 271 |
EBF4,PLXNA2 |
| 3.984e-02 | -3.22 | pancreas | COSMIC cancer mutations | pancreas | 16982 | 279 | 17385 | 281 |
ARHGAP26,ACVR1,DUSP8,LGR4,RECK,LSM11,ALG1L,CEBPA,PRKCA,ABHD6,NCS1,EPDR1,PMAIP1,CFHR1,TMEM37,TSHR,TBC1D8,KLHL23,KLHL3,WISP3,EXOC6B,DSTN,BNIP3L,SLC25A28,ABCC2,TNS1,ACVR2B,SAV1,SPATA9,PLK2,RASGRF2,ALDOA,ARHGAP28,MAPK13,TMOD2,TANC2,SCN5A,TMEM63C,ZHX3,CYP2J2,SLC36A4,TNFRSF10C,DYNC1I1,HPCAL4,NIPSNAP3B,MTUS1,IL17D,RALGPS2,MYC,ZIC5,SRGAP1,MOXD1,STXBP1,GPR161,EPB41L5,BDNF,QSOX1,SHISA2,ARRDC4,OR11H4,ZNF558,ADAMTS3,ISM1,LRRIQ3,QPCTL,EMILIN2,CLMN,IQSEC2,SMYD3,ZNF516,RASAL2,ST14,C4A,FAM131C,CCDC110,PLXNA2,COLEC10,TIAM2,TMEM53,ZNF827,KMO,DACT1,DAB2IP,PJA1,PDE4D,RAB27B,DNAH5,ATP6AP1L,KIAA1549,C3orf67,DZANK1,GAPDH,PDK1,SOX21,CYB5R2,SFXN4,ADCY1,NLGN4X,SATB2,WNT11,RAB38,TBC1D16,TRIQK,IQCK,WFS1,WWTR1,PLEKHG1,P4HA1,TNFSF15,DBP,KLHL31,COBL,KCTD1,C2orf88,CCDC148,MXI1,TMEM132C,BACE1,BIK,CCNJL,KIF5C,ARL2,GAS6,ZNF219,NEO1,RGS17,GPR155,SMPDL3A,PARP9,TMC7,MN1,B9D1,SLC40A1,PXN,MPP1,GPR137C,GPLD1,TRIB3,FGR,GNAO1,MYOM2,TNFRSF17,DDIT3,B4GALT7,PHC1,CCDC126,ACSL1,HEBP1,PTPN21,NDRG2,NRN1,ABAT,ITPR2,SLC2A13,CACNB4,ABHD4,HMCN1,EPCAM,PPM1E,FKBP9,CPNE2,MARVELD2,DLX6,TMEM143,TLN2,FANK1,OR2W3,ZNF391,PGBD5,PNRC1,CAPN5,ATOX1,TTC22,PLEKHA1,SGK2,NT5DC2,PLEKHB1,DYRK1B,SPNS1,TCF7L1,ERN1,DLX2,APBA2,GPR63,LONRF1,RGS16,RUNX2,ZNF395,BVES,SCART1,FBXO4,UBASH3B,CYP4V2,ATP6V1E2,RASL11B,SETBP1,CHADL,SATB1,PFN2,FHOD3,NUMBL,SLC30A4,GAN,EBF4,BNIP3,NCEH1,VGLL4,BARX1,IL17RD,SPATA13,EFNA3,MAFB,STRADB,WWC1,WDR25,PPFIA4,LHPP,PRDM1,B4GALNT3,KIAA0355,HK2,RNF122,DOCK1,RHPN2,FAM198B,KIF21B,RADIL,CBLN1,KCTD15,RPS6KL1,EEPD1,ZDHHC23,ZNF521,MAP7,MYH15,TMEM120B,FAM78B,HSPA2,PHLDB2,UROS,SLC39A8,PTPN6,JAM3,CENPV,IFT81,LMLN,ANKRD31,RBPMS2,DISP1,NECAB2,PRSS16,ARHGEF11,BLVRB,OVOL2,PRKCD,RASD2,EHD3,GTF2F2,ACTA2,PRICKLE2,TRIM3,SGK1,CCDC122,KIAA0408,MSX1,NUAK2,OGDHL,EXOG,PALLD,TLR6,CTIF,RERE,FMO4,MAP2K6,KIAA0513,ZNF474,THAP10,RNF157,PKIA |
| 3.987e-02 | -3.22 | GSE21063_CTRL_VS_ANTI_IGM_STIM_BCELL_3H_DN | MSigDB lists | GSE21063_CTRL_VS_ANTI_IGM_STIM_BCELL_3H_DN | 154 | 6 | 17377 | 282 |
SLC36A4,MXI1,RALGPS2,SLC30A4,VGLL4,DACT1 |
| 3.987e-02 | -3.22 | GSE37301_HEMATOPOIETIC_STEM_CELL_VS_LYMPHOID_PRIMED_MPP_DN | MSigDB lists | GSE37301_HEMATOPOIETIC_STEM_CELL_VS_LYMPHOID_PRIMED_MPP_DN | 154 | 6 | 17377 | 282 |
PHLDB2,FKBP9,ACVR1,PALLD,STXBP1,KCTD1 |
| 3.994e-02 | -3.22 | - | gene3d domains | 3.40.50.1240 | 18 | 2 | 8148 | 145 |
PXYLP1,UBASH3B |
| 4.001e-02 | -3.22 | GO_TRANSCRIPTION_FACTOR_ACTIVITY_RNA_POLYMERASE_II_CORE_PROMOTER_PROXIMAL_REGION_SEQUENCE_SPECIFIC_BINDING | MSigDB lists | GO_TRANSCRIPTION_FACTOR_ACTIVITY_RNA_POLYMERASE_II_CORE_PROMOTER_PROXIMAL_REGION_SEQUENCE_SPECIFIC_BINDING | 325 | 10 | 17377 | 282 |
MSX1,RUNX2,MYC,EBF4,MAFB,CEBPA,PRDM1,DBP,ZNF219,DDIT3 |
| 4.002e-02 | -3.22 | V$AREB6_04 | MSigDB lists | V$AREB6_04 | 237 | 8 | 17377 | 282 |
BDNF,MXI1,CCDC148,PXN,ZNF521,MAFB,PRDM1,TNFRSF17 |
| 4.002e-02 | -3.22 | REACTOME_AXON_GUIDANCE | MSigDB lists | REACTOME_AXON_GUIDANCE | 237 | 8 | 17377 | 282 |
SCN5A,ARHGEF11,DOCK1,PLXNA2,SRGAP1,PFN2,CACNB4,NEO1 |
| 4.003e-02 | -3.22 | cell projection morphogenesis | biological process | GO:0048858 | 481 | 13 | 17256 | 270 |
NUMBL,BDNF,PLXNA2,EFNA3,ADCY1,KIF5C,SGK1,DAB2IP,PRKCA,STXBP1,COBL,RERE,NEO1 |
| 4.003e-02 | -3.22 | PLK2 and PLK4 events | Pathway Interaction DB | plk2_4pathway | 2 | 1 | 2226 | 45 |
PLK2 |
| 4.007e-02 | -3.22 | regulation of cellular localization | biological process | GO:0060341 | 785 | 19 | 17256 | 270 |
BDNF,NECAB2,BVES,FBXO4,PTPN6,UBASH3B,BNIP3L,WWC1,GAS6,PFN2,GPLD1,FGR,PMAIP1,KMO,PRKCD,PDE4D,STXBP1,PKIA,PARP9 |
| 4.011e-02 | -3.22 | GO_CYTOSKELETON | MSigDB lists | GO_CYTOSKELETON | 1809 | 39 | 17377 | 282 |
ARHGAP26,PTPN21,ARL2,KIF5C,NDRG2,KIF21B,DYNC1I1,RADIL,PFN2,FHOD3,MTUS1,GAN,GTF2F2,MAP7,ACTA2,MYH15,PDE4D,TLN2,DNAH5,HSPA2,B9D1,EPB41L5,PHLDB2,GAPDH,PXN,KLHL3,MPP1,DSTN,TNS1,PALLD,CENPV,IFT81,FGR,MAP2K6,PLK2,ALDOA,MYOM2,TMOD2,COBL |
| 4.014e-02 | -3.22 | His_PPase_superfam | interpro domains | IPR029033 | 20 | 2 | 18492 | 296 |
PXYLP1,UBASH3B |
| 4.014e-02 | -3.22 | cation transmembrane transporter activity | molecular function | GO:0008324 | 661 | 17 | 17224 | 278 |
SLC40A1,SCN5A,TMEM63C,SLC30A4,SLC9C1,SLC39A8,ATOX1,ATP6V1E2,SLC36A4,SLC25A28,ITPR2,GAS6,TMEM37,SLC2A13,CACNB4,ATP6AP1L,NCS1 |
| 4.017e-02 | -3.21 | muscle cell differentiation | biological process | GO:0042692 | 246 | 8 | 17256 | 270 |
DYRK1B,ACVR1,BVES,TMOD2,MYOM2,SMYD3,FHOD3,MYORG |
| 4.017e-02 | -3.21 | regulation of heart contraction | biological process | GO:0008016 | 246 | 8 | 17256 | 270 |
SCN5A,BVES,CYP2J2,GNAO1,EHD3,PDE4D,ITPR2,CACNB4 |
| 4.017e-02 | -3.21 | negative regulation of cell-cell adhesion | biological process | GO:0022408 | 160 | 6 | 17256 | 270 |
EPB41L5,EPCAM,ABAT,PTPN6,UBASH3B,PRKCD |
| 4.017e-02 | -3.21 | response to stimulus | biological process | GO:0050896 | 8006 | 140 | 17256 | 270 |
ARHGAP26,ACSL1,ACVR1,LGR4,HEBP1,NDRG2,CEBPA,ITPR2,ABAT,PRKCA,HMCN1,NCS1,EPCAM,CPNE2,PPM1E,PMAIP1,CFHR1,EPHB6,OR2W3,TSHR,WISP3,ATOX1,CAPN5,BNIP3L,ABCC2,ACVR2B,PLEKHA1,SGK2,SAV1,GRK3,PLEKHB1,SPNS1,TCF7L1,RASGRF2,PLK2,ERN1,ALDOA,ARHGAP28,MAPK13,GPR63,SCN5A,RGS16,RUNX2,SCART1,BVES,CYP2J2,FBXO4,UBASH3B,CYP4V2,ATP6V1E2,RASL11B,SLC36A4,TNFRSF10C,SATB1,HPCAL4,IL17D,NUMBL,SLC30A4,RALGPS2,MYC,SRGAP1,INAVA,BNIP3,NCEH1,STXBP1,GPR161,EPB41L5,BDNF,QSOX1,IL17RD,EFNA3,WWC1,STRADB,PRDM1,ARRDC4,OR11H4,HK2,SMYD3,ZNF516,RASAL2,SCAMP1,DOCK1,C4A,PLXNA2,RHPN2,COLEC10,RADIL,TIAM2,KMO,DACT1,RPS6KL1,EEPD1,MAP7,DAB2IP,PDE4D,RAB27B,HSPA2,GAPDH,UROS,PDK1,PTPN6,ADCY1,WNT11,SATB2,RAB38,JAM3,WFS1,WWTR1,TNFSF15,DISP1,ARHGEF11,KIF5C,SLX1B,GAS6,ZNF219,NEO1,GPR155,PRKCD,EHD3,RASD2,GTF2F2,ACTA2,SGK1,PRICKLE2,PARP9,B9D1,SLC40A1,MSX1,PXN,MPP1,NUAK2,GAREM1,TLR6,GPLD1,TRIB3,FGR,GNAO1,MAP2K6,TNFRSF17,DDIT3 |
| 4.019e-02 | -3.21 | GO_NEGATIVE_REGULATION_OF_INTRACELLULAR_SIGNAL_TRANSDUCTION | MSigDB lists | GO_NEGATIVE_REGULATION_OF_INTRACELLULAR_SIGNAL_TRANSDUCTION | 417 | 12 | 17377 | 282 |
RASAL2,DUSP8,DACT1,PTPN6,MYC,WFS1,PRKCD,NDRG2,WWC1,DAB2IP,PLEKHA1,DDIT3 |
| 4.021e-02 | -3.21 | HALLMARK_IL2_STAT5_SIGNALING | MSigDB lists | HALLMARK_IL2_STAT5_SIGNALING | 195 | 7 | 17377 | 282 |
P4HA1,RGS16,SLC39A8,MYC,SMPDL3A,NCS1,HK2 |
| 4.021e-02 | -3.21 | GSE26343_UNSTIM_VS_LPS_STIM_NFAT5_KO_MACROPHAGE_DN | MSigDB lists | GSE26343_UNSTIM_VS_LPS_STIM_NFAT5_KO_MACROPHAGE_DN | 195 | 7 | 17377 | 282 |
PRDM1,FGR,ZNF516,ACSL1,PNRC1,PLK2,SPATA13 |
| 4.021e-02 | -3.21 | GO_REGULATION_OF_ION_HOMEOSTASIS | MSigDB lists | GO_REGULATION_OF_ION_HOMEOSTASIS | 195 | 7 | 17377 | 282 |
SCN5A,ITPR2,PDE4D,SLC30A4,UBASH3B,PTPN6,DDIT3 |
| 4.025e-02 | -3.21 | LPA receptor mediated events | Pathway Interaction DB | lysophospholipid_pathway | 65 | 4 | 2226 | 45 |
PXN,GNAO1,PRKCD,ADCY1 |
| 4.037e-02 | -3.21 | regulation of organelle organization | biological process | GO:0033043 | 1212 | 27 | 17256 | 270 |
PHLDB2,PXN,MSX1,FBXO4,DSTN,BIK,BNIP3L,ARL2,SLX1B,WNT11,PFN2,TBC1D16,JAM3,CENPV,FHOD3,PPM1E,PMAIP1,PLK2,MYC,PRKCD,EHD3,HK2,ARHGAP28,TMOD2,BNIP3,STXBP1,TBC1D8 |
| 4.038e-02 | -3.21 | nucleoside monophosphate biosynthetic process | biological process | GO:0009124 | 120 | 5 | 17256 | 270 |
LHPP,GAPDH,ALDOA,OGDHL,HK2 |
| 4.042e-02 | -3.21 | HORIUCHI_WTAP_TARGETS_UP | MSigDB lists | HORIUCHI_WTAP_TARGETS_UP | 281 | 9 | 17377 | 282 |
ARHGAP26,SLC40A1,RECK,MAFB,ACTA2,ITPR2,ACVR2B,TANC2,HMCN1 |
| 4.058e-02 | -3.20 | large_intestine-rectum-carcinoma-adenocarcinoma | COSMIC cancer mutations | large_intestine-rectum-carcinoma-adenocarcinoma | 16326 | 271 | 17385 | 281 |
ARHGAP26,ACVR1,DUSP8,LGR4,RECK,LSM11,ALG1L,CEBPA,PRKCA,ABHD6,NCS1,EPDR1,PMAIP1,CFHR1,TMEM37,TSHR,TBC1D8,KLHL23,KLHL3,WISP3,EXOC6B,DSTN,BNIP3L,SLC25A28,ABCC2,TNS1,ACVR2B,SAV1,SPATA9,PLK2,RASGRF2,ALDOA,ARHGAP28,MAPK13,TMOD2,TANC2,SCN5A,TMEM63C,ZHX3,CYP2J2,SLC36A4,TNFRSF10C,DYNC1I1,HPCAL4,NIPSNAP3B,MTUS1,IL17D,RALGPS2,MYC,ZIC5,SRGAP1,MOXD1,STXBP1,GPR161,EPB41L5,BDNF,QSOX1,SHISA2,ARRDC4,OR11H4,ZNF558,ADAMTS3,ISM1,LRRIQ3,QPCTL,EMILIN2,CLMN,IQSEC2,SMYD3,ZNF516,RASAL2,ST14,FAM131C,C4A,CCDC110,PLXNA2,COLEC10,TIAM2,TMEM53,ZNF827,KMO,DACT1,DAB2IP,PJA1,PDE4D,RAB27B,DNAH5,ATP6AP1L,C3orf67,DZANK1,GAPDH,PDK1,SOX21,CYB5R2,SFXN4,ADCY1,NLGN4X,SATB2,WNT11,RAB38,TBC1D16,IQCK,WFS1,WWTR1,PLEKHG1,P4HA1,TNFSF15,DBP,KLHL31,COBL,KCTD1,C2orf88,MXI1,TMEM132C,BACE1,BIK,CCNJL,KIF5C,ARL2,GAS6,ZNF219,NEO1,RGS17,GPR155,SMPDL3A,PARP9,TMC7,MN1,SLC40A1,PXN,MPP1,GPR137C,GPLD1,TRIB3,FGR,GNAO1,MYOM2,TNFRSF17,DDIT3,B4GALT7,PHC1,CCDC126,ACSL1,HEBP1,PTPN21,NDRG2,NRN1,ABAT,ITPR2,SLC2A13,CACNB4,ABHD4,HMCN1,EPCAM,PPM1E,FKBP9,CPNE2,MARVELD2,DLX6,TMEM143,TLN2,FANK1,OR2W3,ZNF391,PGBD5,PNRC1,CAPN5,TTC22,PLEKHA1,SGK2,NT5DC2,PLEKHB1,DYRK1B,SPNS1,TCF7L1,ERN1,DLX2,APBA2,GPR63,LONRF1,RGS16,RUNX2,ZNF395,BVES,FBXO4,UBASH3B,CYP4V2,ATP6V1E2,RASL11B,SETBP1,SATB1,PFN2,FHOD3,NUMBL,SLC30A4,GAN,EBF4,BNIP3,NCEH1,VGLL4,BARX1,IL17RD,SPATA13,EFNA3,MAFB,STRADB,WWC1,WDR25,PPFIA4,LHPP,PRDM1,B4GALNT3,KIAA0355,HK2,RNF122,DOCK1,RHPN2,FAM198B,KIF21B,RADIL,CBLN1,KCTD15,RPS6KL1,ZDHHC23,EEPD1,ZNF521,MAP7,MYH15,TMEM120B,HSPA2,FAM78B,PHLDB2,UROS,PTPN6,SLC39A8,JAM3,CENPV,IFT81,LMLN,RBPMS2,DISP1,PRSS16,ARHGEF11,BLVRB,SLX1B,OVOL2,PRKCD,RASD2,EHD3,GTF2F2,ACTA2,PRICKLE2,TRIM3,SGK1,CCDC122,KIAA0408,MSX1,NUAK2,OGDHL,EXOG,PALLD,TLR6,CTIF,RERE,FMO4,MAP2K6,KIAA0513,ZNF474,THAP10,RNF157,PKIA |
| 4.061e-02 | -3.20 | BCAT_GDS748_UP | MSigDB lists | BCAT_GDS748_UP | 47 | 3 | 17377 | 282 |
WNT11,PDE4D,DYNC1I1 |
| 4.061e-02 | -3.20 | GO_HEXOSE_CATABOLIC_PROCESS | MSigDB lists | GO_HEXOSE_CATABOLIC_PROCESS | 47 | 3 | 17377 | 282 |
GAPDH,ALDOA,HK2 |
| 4.061e-02 | -3.20 | MODULE_312 | MSigDB lists | MODULE_312 | 47 | 3 | 17377 | 282 |
BNIP3,BIK,BNIP3L |
| 4.061e-02 | -3.20 | PID_IL6_7_PATHWAY | MSigDB lists | PID_IL6_7_PATHWAY | 47 | 3 | 17377 | 282 |
MAP2K6,MYC,PRKCD |
| 4.061e-02 | -3.20 | EBAUER_TARGETS_OF_PAX3_FOXO1_FUSION_DN | MSigDB lists | EBAUER_TARGETS_OF_PAX3_FOXO1_FUSION_DN | 47 | 3 | 17377 | 282 |
ARHGAP26,ABAT,PGBD5 |
| 4.073e-02 | -3.20 | - | gene3d domains | 2.120.10.80 | 73 | 4 | 8148 | 145 |
KLHL31,KLHL3,KLHL23,GAN |
| 4.074e-02 | -3.20 | AGGAAGC,MIR-516-3P | MSigDB lists | AGGAAGC,MIR-516-3P | 116 | 5 | 17377 | 282 |
SATB2,HERC6,B4GALT7,MTUS1,BNIP3L |
| 4.074e-02 | -3.20 | GSE22611_NOD2_TRANSD_VS_CTRL_TRANSD_HEK293_MDP_STIM_2H_DN | MSigDB lists | GSE22611_NOD2_TRANSD_VS_CTRL_TRANSD_HEK293_MDP_STIM_2H_DN | 116 | 5 | 17377 | 282 |
CLMN,MYOM2,ACVR2B,BVES,ADCY1 |
| 4.074e-02 | -3.20 | GO_REGULATION_OF_DENDRITE_DEVELOPMENT | MSigDB lists | GO_REGULATION_OF_DENDRITE_DEVELOPMENT | 116 | 5 | 17377 | 282 |
SGK1,NUMBL,DAB2IP,COBL,PLK2 |
| 4.074e-02 | -3.20 | REACTOME_INTEGRATION_OF_ENERGY_METABOLISM | MSigDB lists | REACTOME_INTEGRATION_OF_ENERGY_METABOLISM | 116 | 5 | 17377 | 282 |
ITPR2,PRKCA,STXBP1,GNAO1,ADCY1 |
| 4.081e-02 | -3.20 | HES1 (hes family bHLH transcription factor 1) | protein interactions | 3280 | 46 | 3 | 17029 | 283 |
GAPDH,RUNX2,PRKCA |
| 4.081e-02 | -3.20 | ID1 (inhibitor of DNA binding 1, HLH protein) | protein interactions | 3397 | 46 | 3 | 17029 | 283 |
STXBP1,MPP1,B4GALT7 |
| 4.081e-02 | -3.20 | MYH14 (myosin heavy chain 14) | protein interactions | 79784 | 46 | 3 | 17029 | 283 |
SGK1,LGR4,GAN |
| 4.081e-02 | -3.20 | FSCN1 (fascin actin-bundling protein 1) | protein interactions | 6624 | 46 | 3 | 17029 | 283 |
ACTA2,PRKCA,PRKCD |
| 4.092e-02 | -3.20 | DENND1A (DENN domain containing 1A) | protein interactions | 57706 | 78 | 4 | 17029 | 283 |
PHLDB2,RALGPS2,RASAL2,TANC2 |
| 4.092e-02 | -3.20 | RTKN (rhotekin) | protein interactions | 6242 | 78 | 4 | 17029 | 283 |
PHLDB2,RALGPS2,RASAL2,TANC2 |
| 4.094e-02 | -3.20 | GTCTTCC,MIR-7 | MSigDB lists | GTCTTCC,MIR-7 | 155 | 6 | 17377 | 282 |
PDE4D,ZNF395,SATB1,PFN2,BACE1,HPCAL4 |
| 4.094e-02 | -3.20 | SMIRNOV_CIRCULATING_ENDOTHELIOCYTES_IN_CANCER_UP | MSigDB lists | SMIRNOV_CIRCULATING_ENDOTHELIOCYTES_IN_CANCER_UP | 155 | 6 | 17377 | 282 |
QSOX1,TNS1,RGS16,ACSL1,ZNF395,MPP1 |
| 4.102e-02 | -3.19 | TTGCACT,MIR-130A,MIR-301,MIR-130B | MSigDB lists | TTGCACT,MIR-130A,MIR-301,MIR-130B | 372 | 11 | 17377 | 282 |
LONRF1,CCDC126,ACVR1,ACSL1,RUNX2,SOX21,ADCY1,TRIM3,MAFB,VGLL4,TBC1D8 |
| 4.102e-02 | -3.19 | HAN_SATB1_TARGETS_UP | MSigDB lists | HAN_SATB1_TARGETS_UP | 372 | 11 | 17377 | 282 |
BDNF,PXN,RUNX2,ZNF395,MPP1,TNFSF15,TNS1,PRKCA,SATB1,PKIA,MTUS1 |
| 4.106e-02 | -3.19 | Proteoglycans in cancer | KEGG pathways | ko05205 | 203 | 7 | 7161 | 113 |
MAPK13,WNT11,PXN,ITPR2,PRKCA,PTPN6,MYC |
| 4.106e-02 | -3.19 | Proteoglycans in cancer | KEGG pathways | hsa05205 | 203 | 7 | 7161 | 113 |
MAPK13,WNT11,PXN,ITPR2,PRKCA,PTPN6,MYC |
| 4.107e-02 | -3.19 | negative regulation of nucleic acid-templated transcription | biological process | GO:1903507 | 1214 | 27 | 17256 | 270 |
RUNX2,MSX1,MXI1,LGR4,ZHX3,WWC1,SATB2,WNT11,CEBPA,PRDM1,GAS6,ACVR2B,OVOL2,ZNF219,SATB1,RERE,TRIB3,DACT1,WFS1,MYC,WWTR1,DAB2IP,DLX2,KCTD1,PKIA,DDIT3,PARP9 |
| 4.114e-02 | -3.19 | GO_M_BAND | MSigDB lists | GO_M_BAND | 20 | 2 | 17377 | 282 |
MYOM2,ALDOA |
| 4.114e-02 | -3.19 | WALLACE_PROSTATE_CANCER_UP | MSigDB lists | WALLACE_PROSTATE_CANCER_UP | 20 | 2 | 17377 | 282 |
ST14,MYC |
| 4.114e-02 | -3.19 | WELCH_GATA1_TARGETS | MSigDB lists | WELCH_GATA1_TARGETS | 20 | 2 | 17377 | 282 |
UROS,HEBP1 |
| 4.114e-02 | -3.19 | GO_ZINC_ION_HOMEOSTASIS | MSigDB lists | GO_ZINC_ION_HOMEOSTASIS | 20 | 2 | 17377 | 282 |
SLC30A4,SLC39A8 |
| 4.114e-02 | -3.19 | GO_REGULATION_OF_SYNAPTIC_VESICLE_EXOCYTOSIS | MSigDB lists | GO_REGULATION_OF_SYNAPTIC_VESICLE_EXOCYTOSIS | 20 | 2 | 17377 | 282 |
STXBP1,PFN2 |
| 4.114e-02 | -3.19 | GO_ACTIN_MONOMER_BINDING | MSigDB lists | GO_ACTIN_MONOMER_BINDING | 20 | 2 | 17377 | 282 |
PFN2,COBL |
| 4.115e-02 | -3.19 | KARLSSON_TGFB1_TARGETS_DN | MSigDB lists | KARLSSON_TGFB1_TARGETS_DN | 196 | 7 | 17377 | 282 |
NDRG2,PNRC1,DUSP8,ZNF395,WWTR1,MTUS1,BNIP3L |
| 4.115e-02 | -3.19 | CAIRO_HEPATOBLASTOMA_UP | MSigDB lists | CAIRO_HEPATOBLASTOMA_UP | 196 | 7 | 17377 | 282 |
CLMN,EPCAM,PRKCA,PALLD,HSPA2,SMYD3,WFS1 |
| 4.115e-02 | -3.19 | GO_TRANSMEMBRANE_RECEPTOR_PROTEIN_KINASE_ACTIVITY | MSigDB lists | GO_TRANSMEMBRANE_RECEPTOR_PROTEIN_KINASE_ACTIVITY | 80 | 4 | 17377 | 282 |
ACVR2B,EPHB6,ACVR1,EFNA3 |
| 4.118e-02 | -3.19 | complement activation | biological process | GO:0006956 | 49 | 3 | 17256 | 270 |
COLEC10,CFHR1,C4A |
| 4.120e-02 | -3.19 | cardiac chamber development | biological process | GO:0003205 | 161 | 6 | 17256 | 270 |
SCN5A,WNT11,PRDM1,OVOL2,ACVR1,SAV1 |
| 4.122e-02 | -3.19 | purine ribonucleoside triphosphate biosynthetic process | biological process | GO:0009206 | 83 | 4 | 17256 | 270 |
GAPDH,ALDOA,OGDHL,HK2 |
| 4.122e-02 | -3.19 | regulation of coagulation | biological process | GO:0050818 | 83 | 4 | 17256 | 270 |
ABAT,PRKCA,UBASH3B,PRKCD |
| 4.127e-02 | -3.19 | GGGTGGRR_V$PAX4_03 | MSigDB lists | GGGTGGRR_V$PAX4_03 | 1223 | 28 | 17377 | 282 |
MN1,ARHGAP26,MXI1,ACVR1,PXN,RASAL2,DUSP8,PTPN6,BLVRB,CAPN5,NDRG2,RASL11B,TNS1,PRDM1,OVOL2,RADIL,HPCAL4,MTUS1,ZNF827,NUMBL,GNAO1,ZIC5,HK2,ZNF521,DAB2IP,PJA1,EPHB6,PKIA |
| 4.140e-02 | -3.18 | FERM_central | interpro domains | IPR019748 | 48 | 3 | 18492 | 296 |
EPB41L5,TLN2,PTPN21 |
| 4.140e-02 | -3.18 | FERM_domain | interpro domains | IPR000299 | 48 | 3 | 18492 | 296 |
EPB41L5,TLN2,PTPN21 |
| 4.149e-02 | -3.18 | DAP12 interactions | REACTOME pathways | R-HSA-2172127 | 371 | 10 | 10287 | 148 |
IL17RD,TRIB3,RASAL2,DUSP8,RASGRF2,PRKCD,ADCY1,DAB2IP,ITPR2,PRKCA |
| 4.155e-02 | -3.18 | haematopoietic_neoplasm | COSMIC cancer mutations | haematopoietic_neoplasm | 11378 | 198 | 17385 | 281 |
ARHGAP26,ACSL1,ACVR1,LGR4,RECK,PTPN21,ALG1L,CEBPA,ITPR2,ABAT,PRKCA,ABHD4,CACNB4,HMCN1,NCS1,CPNE2,PPM1E,PMAIP1,MARVELD2,CFHR1,TLN2,OR2W3,TSHR,FANK1,TBC1D8,PGBD5,ZNF391,KLHL23,WISP3,EXOC6B,CAPN5,BNIP3L,TTC22,ABCC2,TNS1,ACVR2B,SGK2,PLEKHB1,SPNS1,DYRK1B,TCF7L1,PLK2,RASGRF2,ERN1,ALDOA,ARHGAP28,MAPK13,TMOD2,TANC2,APBA2,LONRF1,GPR63,TMEM63C,SCN5A,RUNX2,ZHX3,BVES,UBASH3B,CYP2J2,CYP4V2,SETBP1,SLC36A4,SATB1,DYNC1I1,HPCAL4,NIPSNAP3B,FHOD3,MTUS1,NUMBL,RALGPS2,SLC30A4,MYC,SRGAP1,NCEH1,MOXD1,STXBP1,EPB41L5,BDNF,IL17RD,QSOX1,SPATA13,PPFIA4,WDR25,WWC1,STRADB,SHISA2,PRDM1,LHPP,B4GALNT3,ADAMTS3,KIAA0355,ISM1,LRRIQ3,QPCTL,EMILIN2,HK2,CLMN,IQSEC2,RNF122,SMYD3,ZNF516,RASAL2,DOCK1,FAM131C,C4A,CCDC110,PLXNA2,RHPN2,COLEC10,KIF21B,RADIL,TIAM2,ZNF827,TMEM53,KCTD15,KMO,RPS6KL1,DACT1,ZNF521,ZDHHC23,EEPD1,MAP7,MYH15,PJA1,PDE4D,DNAH5,FAM78B,C3orf67,DZANK1,PHLDB2,GAPDH,UROS,PDK1,SLC39A8,PTPN6,CYB5R2,SFXN4,ADCY1,NLGN4X,SATB2,WNT11,TBC1D16,JAM3,IQCK,LMLN,ANKRD31,WFS1,RBPMS2,PLEKHG1,TNFSF15,DISP1,DBP,KLHL31,COBL,CCDC148,MXI1,NECAB2,TMEM132C,ARHGEF11,CCNJL,ZNF219,NEO1,RGS17,GPR155,PRKCD,GTF2F2,ACTA2,PRICKLE2,TRIM3,SGK1,CCDC122,KIAA0408,SMPDL3A,PARP9,TMC7,MN1,SLC40A1,MSX1,OGDHL,NUAK2,PALLD,TLR6,GPR137C,RERE,CTIF,GPLD1,TRIB3,FGR,GNAO1,FMO4,MAP2K6,KIAA0513,MYOM2,ZNF474,TNFRSF17,RNF157,DDIT3,PHC1 |
| 4.158e-02 | -3.18 | rectum | COSMIC cancer mutations | rectum | 16329 | 271 | 17385 | 281 |
ARHGAP26,ACVR1,DUSP8,LGR4,RECK,LSM11,ALG1L,CEBPA,PRKCA,ABHD6,NCS1,EPDR1,PMAIP1,CFHR1,TMEM37,TSHR,TBC1D8,KLHL23,KLHL3,WISP3,EXOC6B,DSTN,BNIP3L,SLC25A28,ABCC2,TNS1,ACVR2B,SAV1,SPATA9,PLK2,RASGRF2,ALDOA,ARHGAP28,MAPK13,TMOD2,TANC2,SCN5A,TMEM63C,ZHX3,CYP2J2,SLC36A4,TNFRSF10C,DYNC1I1,HPCAL4,NIPSNAP3B,MTUS1,IL17D,RALGPS2,MYC,ZIC5,SRGAP1,MOXD1,STXBP1,GPR161,EPB41L5,BDNF,QSOX1,SHISA2,ARRDC4,OR11H4,ZNF558,ADAMTS3,ISM1,LRRIQ3,QPCTL,EMILIN2,CLMN,IQSEC2,SMYD3,ZNF516,RASAL2,ST14,FAM131C,C4A,CCDC110,PLXNA2,COLEC10,TIAM2,TMEM53,ZNF827,KMO,DACT1,DAB2IP,PJA1,PDE4D,RAB27B,DNAH5,ATP6AP1L,C3orf67,DZANK1,GAPDH,PDK1,SOX21,CYB5R2,SFXN4,ADCY1,NLGN4X,SATB2,WNT11,RAB38,TBC1D16,IQCK,WFS1,WWTR1,PLEKHG1,P4HA1,TNFSF15,DBP,KLHL31,COBL,KCTD1,C2orf88,MXI1,TMEM132C,BACE1,BIK,CCNJL,KIF5C,ARL2,GAS6,ZNF219,NEO1,RGS17,GPR155,SMPDL3A,PARP9,TMC7,MN1,SLC40A1,PXN,MPP1,GPR137C,GPLD1,TRIB3,FGR,GNAO1,MYOM2,TNFRSF17,DDIT3,B4GALT7,PHC1,CCDC126,ACSL1,HEBP1,PTPN21,NDRG2,NRN1,ABAT,ITPR2,SLC2A13,CACNB4,ABHD4,HMCN1,EPCAM,PPM1E,FKBP9,CPNE2,MARVELD2,DLX6,TMEM143,TLN2,FANK1,OR2W3,ZNF391,PGBD5,PNRC1,CAPN5,TTC22,PLEKHA1,SGK2,NT5DC2,PLEKHB1,DYRK1B,SPNS1,TCF7L1,ERN1,DLX2,APBA2,GPR63,LONRF1,RGS16,RUNX2,ZNF395,BVES,FBXO4,UBASH3B,CYP4V2,ATP6V1E2,RASL11B,SETBP1,SATB1,PFN2,FHOD3,NUMBL,SLC30A4,GAN,EBF4,BNIP3,NCEH1,VGLL4,BARX1,IL17RD,SPATA13,EFNA3,MAFB,STRADB,WWC1,WDR25,PPFIA4,LHPP,PRDM1,B4GALNT3,KIAA0355,HK2,RNF122,DOCK1,RHPN2,FAM198B,KIF21B,RADIL,CBLN1,KCTD15,RPS6KL1,ZDHHC23,EEPD1,ZNF521,MAP7,MYH15,TMEM120B,HSPA2,FAM78B,PHLDB2,UROS,PTPN6,SLC39A8,JAM3,CENPV,IFT81,LMLN,RBPMS2,DISP1,PRSS16,ARHGEF11,BLVRB,SLX1B,OVOL2,PRKCD,RASD2,EHD3,GTF2F2,ACTA2,PRICKLE2,TRIM3,SGK1,CCDC122,KIAA0408,MSX1,NUAK2,OGDHL,EXOG,PALLD,TLR6,CTIF,RERE,FMO4,MAP2K6,KIAA0513,ZNF474,THAP10,RNF157,PKIA |
| 4.165e-02 | -3.18 | NUFIP1 (NUFIP1, FMR1 interacting protein 1) | protein interactions | 26747 | 114 | 5 | 17029 | 283 |
STXBP1,HPCAL4,GNAO1,NCS1,PLXNA2 |
| 4.178e-02 | -3.18 | negative regulation of RNA biosynthetic process | biological process | GO:1902679 | 1216 | 27 | 17256 | 270 |
RUNX2,MSX1,MXI1,LGR4,ZHX3,WWC1,SATB2,WNT11,CEBPA,PRDM1,GAS6,ACVR2B,OVOL2,ZNF219,SATB1,RERE,TRIB3,DACT1,WFS1,MYC,WWTR1,DAB2IP,DLX2,KCTD1,PKIA,DDIT3,PARP9 |
| 4.179e-02 | -3.18 | endometrioid_carcinoma | COSMIC cancer mutations | endometrioid_carcinoma | 16178 | 269 | 17385 | 281 |
ARHGAP26,ACVR1,DUSP8,LGR4,RECK,LSM11,PRKCA,ABHD6,EPDR1,CFHR1,TMEM37,TSHR,TBC1D8,KLHL23,KLHL3,WISP3,EXOC6B,DSTN,BNIP3L,SLC25A28,ABCC2,TNS1,ACVR2B,SAV1,SPATA9,PLK2,RASGRF2,ALDOA,ARHGAP28,MAPK13,TMOD2,TANC2,SCN5A,TMEM63C,ZHX3,CYP2J2,SLC36A4,TNFRSF10C,DYNC1I1,HPCAL4,NIPSNAP3B,MTUS1,IL17D,RALGPS2,MYC,ZIC5,SRGAP1,MOXD1,STXBP1,GPR161,EPB41L5,BDNF,QSOX1,SHISA2,ARRDC4,OR11H4,ZNF558,ADAMTS3,ISM1,LRRIQ3,QPCTL,EMILIN2,CLMN,IQSEC2,SMYD3,ZNF516,RASAL2,ST14,FAM131C,CCDC110,PLXNA2,COLEC10,TIAM2,TMEM53,ZNF827,KMO,DACT1,DAB2IP,PJA1,PDE4D,RAB27B,DNAH5,ATP6AP1L,C3orf67,DZANK1,GAPDH,PDK1,SOX21,CYB5R2,SFXN4,ADCY1,NLGN4X,SATB2,WNT11,RAB38,TBC1D16,TRIQK,IQCK,WFS1,WWTR1,PLEKHG1,P4HA1,TNFSF15,DBP,KLHL31,COBL,KCTD1,CCDC148,MXI1,TMEM132C,BACE1,BIK,CCNJL,KIF5C,ARL2,ZNF219,NEO1,RGS17,GPR155,SMPDL3A,PARP9,TMC7,MN1,B9D1,SLC40A1,PXN,MPP1,GPR137C,GPLD1,TRIB3,FGR,GNAO1,MYOM2,TNFRSF17,DDIT3,B4GALT7,PHC1,CCDC126,ACSL1,HEBP1,PTPN21,NDRG2,NRN1,ABAT,ITPR2,SLC2A13,CACNB4,ABHD4,HMCN1,EPCAM,PPM1E,FKBP9,CPNE2,MARVELD2,DLX6,TMEM143,TLN2,FANK1,OR2W3,ZNF391,PGBD5,PNRC1,CAPN5,ATOX1,TTC22,PLEKHA1,SGK2,NT5DC2,PLEKHB1,DYRK1B,SPNS1,TCF7L1,ERN1,DLX2,APBA2,GPR63,LONRF1,RGS16,RUNX2,ZNF395,BVES,FBXO4,UBASH3B,CYP4V2,ATP6V1E2,SETBP1,CHADL,SATB1,PFN2,FHOD3,NUMBL,SLC30A4,GAN,EBF4,BNIP3,NCEH1,VGLL4,BARX1,IL17RD,SPATA13,EFNA3,MAFB,STRADB,WWC1,WDR25,PPFIA4,LHPP,PRDM1,B4GALNT3,KIAA0355,HK2,RNF122,DOCK1,RHPN2,FAM198B,KIF21B,RADIL,CBLN1,KCTD15,RPS6KL1,ZDHHC23,EEPD1,ZNF521,MAP7,MYH15,TMEM120B,HSPA2,FAM78B,PHLDB2,UROS,PTPN6,SLC39A8,JAM3,CENPV,IFT81,LMLN,ANKRD31,RBPMS2,DISP1,NECAB2,PRSS16,ARHGEF11,BLVRB,OVOL2,PRKCD,RASD2,EHD3,GTF2F2,ACTA2,PRICKLE2,TRIM3,SGK1,CCDC122,KIAA0408,MSX1,NUAK2,OGDHL,EXOG,PALLD,TLR6,CTIF,RERE,FMO4,MAP2K6,KIAA0513,ZNF474,THAP10,RNF157,PKIA |
| 4.188e-02 | -3.17 | chemical homeostasis | biological process | GO:0048878 | 1054 | 24 | 17256 | 270 |
SLC40A1,SCN5A,KLHL3,SLC9C1,SLC39A8,SFXN4,ATOX1,ADCY1,ATP6V1E2,SLC25A28,ABCC2,CEBPA,ITPR2,GAS6,RAB38,ABHD4,NEO1,SLC30A4,WFS1,MYC,ERN1,HK2,BNIP3,DDIT3 |
| 4.195e-02 | -3.17 | YWHAG (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma) | protein interactions | 7532 | 410 | 12 | 17029 | 283 |
NUMBL,PHLDB2,GAPDH,RALGPS2,RASAL2,PRKCD,WWTR1,SPATA13,KIF5C,WWC1,KIAA0408,PRKCA |
| 4.196e-02 | -3.17 | GTGCCAA,MIR-96 | MSigDB lists | GTGCCAA,MIR-96 | 283 | 9 | 17377 | 282 |
TRIB3,DOCK1,GAN,RHPN2,ABAT,ITPR2,CACNB4,COBL,HSPA2 |
| 4.198e-02 | -3.17 | actin filament-based process | biological process | GO:0030029 | 534 | 14 | 17256 | 270 |
ARHGAP26,EPB41L5,SCN5A,ARHGEF11,DSTN,ALDOA,NUAK2,TMOD2,MYOM2,PALLD,IQSEC2,PFN2,COBL,FHOD3 |
| 4.198e-02 | -3.17 | regulation of trans-synaptic signaling | biological process | GO:0099177 | 340 | 10 | 17256 | 270 |
BDNF,KMO,PLK2,BACE1,NLGN4X,ABAT,STXBP1,ABHD6,PFN2,CBLN1 |
| 4.198e-02 | -3.17 | modulation of chemical synaptic transmission | biological process | GO:0050804 | 340 | 10 | 17256 | 270 |
BDNF,KMO,PLK2,BACE1,NLGN4X,ABAT,STXBP1,ABHD6,PFN2,CBLN1 |
| 4.202e-02 | -3.17 | PDGF_UP.V1_DN | MSigDB lists | PDGF_UP.V1_DN | 117 | 5 | 17377 | 282 |
MAP7,MSX1,DBP,PRSS16,CBLN1 |
| 4.202e-02 | -3.17 | GO_CYTOKINE_PRODUCTION | MSigDB lists | GO_CYTOKINE_PRODUCTION | 117 | 5 | 17377 | 282 |
WNT11,GAS6,ADAMTS3,TLR6,PRKCD |
| 4.202e-02 | -3.17 | REACTOME_SIGNALING_BY_PDGF | MSigDB lists | REACTOME_SIGNALING_BY_PDGF | 117 | 5 | 17377 | 282 |
TRIB3,ITPR2,PRKCA,PRKCD,ADCY1 |
| 4.202e-02 | -3.17 | GSE29615_CTRL_VS_DAY7_LAIV_FLU_VACCINE_PBMC_UP | MSigDB lists | GSE29615_CTRL_VS_DAY7_LAIV_FLU_VACCINE_PBMC_UP | 156 | 6 | 17377 | 282 |
DZANK1,TNFRSF10C,TNFRSF17,RBPMS2,NT5DC2,TBC1D8 |
| 4.202e-02 | -3.17 | GSE15659_NAIVE_VS_PTPRC_NEG_CD4_TCELL_UP | MSigDB lists | GSE15659_NAIVE_VS_PTPRC_NEG_CD4_TCELL_UP | 156 | 6 | 17377 | 282 |
ARHGAP28,FAM198B,ACSL1,DYNC1I1,DACT1,CCDC110 |
| 4.202e-02 | -3.17 | GSE34156_NOD2_LIGAND_VS_TLR1_TLR2_LIGAND_24H_TREATED_MONOCYTE_UP | MSigDB lists | GSE34156_NOD2_LIGAND_VS_TLR1_TLR2_LIGAND_24H_TREATED_MONOCYTE_UP | 156 | 6 | 17377 | 282 |
NDRG2,WNT11,B4GALNT3,BVES,HMCN1,NCS1 |
| 4.206e-02 | -3.17 | GO_CIRCULATORY_SYSTEM_DEVELOPMENT | MSigDB lists | GO_CIRCULATORY_SYSTEM_DEVELOPMENT | 761 | 19 | 17377 | 282 |
B9D1,SCN5A,MSX1,ACVR1,BVES,RECK,WNT11,PRDM1,ACVR2B,OVOL2,SAV1,PRKCA,JAM3,FHOD3,GPLD1,ACTA2,DAB2IP,DNAH5,DDIT3 |
| 4.206e-02 | -3.17 | GO_CARDIOVASCULAR_SYSTEM_DEVELOPMENT | MSigDB lists | GO_CARDIOVASCULAR_SYSTEM_DEVELOPMENT | 761 | 19 | 17377 | 282 |
B9D1,SCN5A,MSX1,ACVR1,BVES,RECK,WNT11,PRDM1,ACVR2B,OVOL2,SAV1,PRKCA,JAM3,FHOD3,GPLD1,ACTA2,DAB2IP,DNAH5,DDIT3 |
| 4.210e-02 | -3.17 | HALLMARK_MTORC1_SIGNALING | MSigDB lists | HALLMARK_MTORC1_SIGNALING | 197 | 7 | 17377 | 282 |
P4HA1,TRIB3,GAPDH,PDK1,ALDOA,DDIT3,HK2 |
| 4.210e-02 | -3.17 | V$TCF11MAFG_01 | MSigDB lists | V$TCF11MAFG_01 | 197 | 7 | 17377 | 282 |
NUMBL,ARHGEF11,SATB1,DYNC1I1,PFN2,BLVRB,ALDOA |
| 4.213e-02 | -3.17 | positive regulation of leukocyte degranulation | biological process | GO:0043302 | 21 | 2 | 17256 | 270 |
FGR,STXBP1 |
| 4.213e-02 | -3.17 | cardiac myofibril assembly | biological process | GO:0055003 | 21 | 2 | 17256 | 270 |
MYOM2,FHOD3 |
| 4.213e-02 | -3.17 | negative regulation of transcription regulatory region DNA binding | biological process | GO:2000678 | 21 | 2 | 17256 | 270 |
MSX1,DDIT3 |
| 4.213e-02 | -3.17 | negative regulation of nucleocytoplasmic transport | biological process | GO:0046823 | 21 | 2 | 17256 | 270 |
GAS6,PKIA |
| 4.213e-02 | -3.17 | cell surface receptor signaling pathway involved in heart development | biological process | GO:0061311 | 21 | 2 | 17256 | 270 |
MSX1,ACVR1 |
| 4.233e-02 | -3.16 | abdomen | COSMIC cancer mutations | abdomen | 615 | 16 | 17385 | 281 |
SCN5A,RECK,EXOC6B,PTPN21,OGDHL,TNS1,ITPR2,B4GALNT3,GPR137C,SATB1,CTIF,SLC30A4,KMO,MYC,WWTR1,DNAH5 |
| 4.239e-02 | -3.16 | central_nervous_system-temporal_lobe-glioma-astrocytoma_Grade_IV | COSMIC cancer mutations | central_nervous_system-temporal_lobe-glioma-astrocytoma_Grade_IV | 48 | 3 | 17385 | 281 |
WWC1,KIAA1549,SPATA13 |
| 4.239e-02 | -3.16 | central_nervous_system-frontal_lobe-glioma-astrocytoma_Grade_IV | COSMIC cancer mutations | central_nervous_system-frontal_lobe-glioma-astrocytoma_Grade_IV | 48 | 3 | 17385 | 281 |
MN1,SCN5A,KIAA1549 |
| 4.248e-02 | -3.16 | RGSPROTEIN | prints domains | PR01301 | 22 | 2 | 4652 | 70 |
RGS17,RGS16 |
| 4.248e-02 | -3.16 | microtubule motor activity | molecular function | GO:0003777 | 118 | 5 | 17224 | 278 |
KIF5C,MYH15,KIF21B,DYNC1I1,DNAH5 |
| 4.256e-02 | -3.16 | V$ER_Q6_02 | MSigDB lists | V$ER_Q6_02 | 240 | 8 | 17377 | 282 |
MAFB,NDRG2,BDNF,PPM1E,OVOL2,SATB1,HPCAL4,EFNA3 |
| 4.256e-02 | -3.16 | MBP (myelin basic protein) | protein interactions | 4155 | 79 | 4 | 17029 | 283 |
DYRK1B,MAPK13,PRKCA,PRKCD |
| 4.269e-02 | -3.15 | cell part | cellular component | GO:0044464 | 16492 | 262 | 18223 | 280 |
ARHGAP26,ACVR1,DUSP8,LGR4,RECK,LSM11,ALG1L,CEBPA,PRKCA,ABHD6,NCS1,EPDR1,PMAIP1,TSHR,TBC1D8,SMIM20,SLC9C1,KLHL23,KLHL3,WISP3,EXOC6B,DSTN,BNIP3L,SLC25A28,ABCC2,TNS1,ACVR2B,SAV1,PLK2,RASGRF2,ALDOA,ARHGAP28,MAPK13,TMOD2,SCN5A,ZHX3,CYP2J2,SLC36A4,TNFRSF10C,HERC6,DYNC1I1,HPCAL4,NIPSNAP3B,MYORG,MTUS1,RALGPS2,MYC,ZIC5,SRGAP1,MOXD1,STXBP1,GPR161,EPB41L5,BDNF,ENAM,QSOX1,SHISA2,ARRDC4,OR11H4,ZNF558,QPCTL,CLMN,IQSEC2,SMYD3,ZNF516,RASAL2,SCAMP1,ST14,C4A,CCDC110,PLXNA2,COLEC10,TIAM2,TMEM53,ZNF827,KMO,DACT1,DAB2IP,PJA1,PDE4D,RAB27B,DNAH5,KIAA1549,GAPDH,PDK1,SOX21,CYB5R2,SFXN4,ADCY1,NLGN4X,SATB2,WNT11,PXYLP1,RAB38,TBC1D16,TRIQK,ZNF697,WFS1,WWTR1,PLEKHG1,P4HA1,TNFSF15,DBP,KLHL31,COBL,KCTD1,C2orf88,MXI1,BACE1,BIK,CCNJL,KIF5C,ARL2,GAS6,ZNF219,NEO1,KDM7A,RGS17,GPR155,PARP9,B9D1,LZTS3,SLC40A1,PXN,MPP1,GAREM1,GPLD1,TRIB3,FGR,GNAO1,MYOM2,TNFRSF17,DDIT3,B4GALT7,PHC1,CCDC126,ACSL1,HEBP1,PTPN21,NDRG2,NRN1,ABAT,ITPR2,SLC2A13,CACNB4,ABHD4,HMCN1,EPCAM,PPM1E,FKBP9,CPNE2,MARVELD2,DLX6,TMEM143,EPHB6,TLN2,FANK1,OR2W3,ZNF391,PGBD5,PNRC1,CAPN5,ATOX1,PLEKHA1,SGK2,GRK3,PLEKHB1,DYRK1B,SPNS1,TCF7L1,ERN1,DLX2,APBA2,GPR63,LONRF1,RGS16,RUNX2,ZNF395,BVES,SCART1,FBXO4,UBASH3B,CYP4V2,ATP6V1E2,SETBP1,SATB1,PFN2,FHOD3,NUMBL,SLC30A4,GAN,EBF4,INAVA,BNIP3,NCEH1,VGLL4,BARX1,IL17RD,B3GLCT,SPATA13,EFNA3,MAFB,STRADB,WWC1,PPFIA4,CATSPERE,LHPP,PRDM1,B4GALNT3,HK2,RNF122,DOCK1,RHPN2,FAM198B,KIF21B,RADIL,CBLN1,RPS6KL1,ZDHHC23,ZNF521,MAP7,MYH15,TMEM120B,HSPA2,PHLDB2,UROS,PTPN6,SLC39A8,JAM3,CENPV,IFT81,LMLN,RBPMS2,DISP1,NECAB2,PRSS16,ARHGEF11,BLVRB,SLX1B,OVOL2,RASD2,EHD3,PRKCD,GTF2F2,PRICKLE2,TRIM3,SGK1,ACTA2,MSX1,CCDC184,NUAK2,OGDHL,EXOG,PALLD,TLR6,CTIF,RERE,FMO4,MAP2K6,KIAA0513,RNF157,PKIA |
| 4.270e-02 | -3.15 | Dopamine Neurotransmitter Release Cycle | REACTOME pathways | R-HSA-212676 | 23 | 2 | 10287 | 148 |
PPFIA4,STXBP1 |
| 4.274e-02 | -3.15 | ACTG1 (actin gamma 1) | protein interactions | 71 | 153 | 6 | 17029 | 283 |
LGR4,PFN2,UBASH3B,MYC,DSTN,GAN |
| 4.274e-02 | -3.15 | GCTNWTTGK_UNKNOWN | MSigDB lists | GCTNWTTGK_UNKNOWN | 284 | 9 | 17377 | 282 |
STRADB,MN1,ENAM,PRDM1,PNRC1,DNAH5,RECK,MAP2K6,RERE |
| 4.274e-02 | -3.15 | MORF_ARL3 | MSigDB lists | MORF_ARL3 | 284 | 9 | 17377 | 282 |
IQCK,MSX1,RUNX2,SCAMP1,DOCK1,PDE4D,TANC2,PLEKHB1,GPLD1 |
| 4.276e-02 | -3.15 | ST_INTEGRIN_SIGNALING_PATHWAY | MSigDB lists | ST_INTEGRIN_SIGNALING_PATHWAY | 81 | 4 | 17377 | 282 |
ARHGAP26,TLN2,DOCK1,RASGRF2 |
| 4.276e-02 | -3.15 | SCHUETZ_BREAST_CANCER_DUCTAL_INVASIVE_DN | MSigDB lists | SCHUETZ_BREAST_CANCER_DUCTAL_INVASIVE_DN | 81 | 4 | 17377 | 282 |
ABAT,PLK2,WFS1,TBC1D8 |
| 4.276e-02 | -3.15 | GO_POSITIVE_REGULATION_OF_EXOCYTOSIS | MSigDB lists | GO_POSITIVE_REGULATION_OF_EXOCYTOSIS | 81 | 4 | 17377 | 282 |
FGR,RAB27B,STXBP1,NCS1 |
| 4.276e-02 | -3.15 | endometrium | COSMIC cancer mutations | endometrium | 16181 | 269 | 17385 | 281 |
ARHGAP26,ACVR1,DUSP8,LGR4,RECK,LSM11,PRKCA,ABHD6,EPDR1,CFHR1,TMEM37,TSHR,TBC1D8,KLHL23,KLHL3,WISP3,EXOC6B,DSTN,BNIP3L,SLC25A28,ABCC2,TNS1,ACVR2B,SAV1,SPATA9,PLK2,RASGRF2,ALDOA,ARHGAP28,MAPK13,TMOD2,TANC2,SCN5A,TMEM63C,ZHX3,CYP2J2,SLC36A4,TNFRSF10C,DYNC1I1,HPCAL4,NIPSNAP3B,MTUS1,IL17D,RALGPS2,MYC,ZIC5,SRGAP1,MOXD1,STXBP1,GPR161,EPB41L5,BDNF,QSOX1,SHISA2,ARRDC4,OR11H4,ZNF558,ADAMTS3,ISM1,LRRIQ3,QPCTL,EMILIN2,CLMN,IQSEC2,SMYD3,ZNF516,RASAL2,ST14,FAM131C,CCDC110,PLXNA2,COLEC10,TIAM2,TMEM53,ZNF827,KMO,DACT1,DAB2IP,PJA1,PDE4D,RAB27B,DNAH5,ATP6AP1L,C3orf67,DZANK1,GAPDH,PDK1,SOX21,CYB5R2,SFXN4,ADCY1,NLGN4X,SATB2,WNT11,RAB38,TBC1D16,TRIQK,IQCK,WFS1,WWTR1,PLEKHG1,P4HA1,TNFSF15,DBP,KLHL31,COBL,KCTD1,CCDC148,MXI1,TMEM132C,BACE1,BIK,CCNJL,KIF5C,ARL2,ZNF219,NEO1,RGS17,GPR155,SMPDL3A,PARP9,TMC7,MN1,B9D1,SLC40A1,PXN,MPP1,GPR137C,GPLD1,TRIB3,FGR,GNAO1,MYOM2,TNFRSF17,DDIT3,B4GALT7,PHC1,CCDC126,ACSL1,HEBP1,PTPN21,NDRG2,NRN1,ABAT,ITPR2,SLC2A13,CACNB4,ABHD4,HMCN1,EPCAM,PPM1E,FKBP9,CPNE2,MARVELD2,DLX6,TMEM143,TLN2,FANK1,OR2W3,ZNF391,PGBD5,PNRC1,CAPN5,ATOX1,TTC22,PLEKHA1,SGK2,NT5DC2,PLEKHB1,DYRK1B,SPNS1,TCF7L1,ERN1,DLX2,APBA2,GPR63,LONRF1,RGS16,RUNX2,ZNF395,BVES,FBXO4,UBASH3B,CYP4V2,ATP6V1E2,SETBP1,CHADL,SATB1,PFN2,FHOD3,NUMBL,SLC30A4,GAN,EBF4,BNIP3,NCEH1,VGLL4,BARX1,IL17RD,SPATA13,EFNA3,MAFB,STRADB,WWC1,WDR25,PPFIA4,LHPP,PRDM1,B4GALNT3,KIAA0355,HK2,RNF122,DOCK1,RHPN2,FAM198B,KIF21B,RADIL,CBLN1,KCTD15,RPS6KL1,ZDHHC23,EEPD1,ZNF521,MAP7,MYH15,TMEM120B,HSPA2,FAM78B,PHLDB2,UROS,PTPN6,SLC39A8,JAM3,CENPV,IFT81,LMLN,ANKRD31,RBPMS2,DISP1,NECAB2,PRSS16,ARHGEF11,BLVRB,OVOL2,PRKCD,RASD2,EHD3,GTF2F2,ACTA2,PRICKLE2,TRIM3,SGK1,CCDC122,KIAA0408,MSX1,NUAK2,OGDHL,EXOG,PALLD,TLR6,CTIF,RERE,FMO4,MAP2K6,KIAA0513,ZNF474,THAP10,RNF157,PKIA |
| 4.277e-02 | -3.15 | purine nucleoside triphosphate biosynthetic process | biological process | GO:0009145 | 84 | 4 | 17256 | 270 |
GAPDH,ALDOA,OGDHL,HK2 |
| 4.282e-02 | -3.15 | GO_GLOMERULUS_DEVELOPMENT | MSigDB lists | GO_GLOMERULUS_DEVELOPMENT | 48 | 3 | 17377 | 282 |
ACTA2,LGR4,WWTR1 |
| 4.282e-02 | -3.15 | GO_NEGATIVE_REGULATION_OF_COAGULATION | MSigDB lists | GO_NEGATIVE_REGULATION_OF_COAGULATION | 48 | 3 | 17377 | 282 |
ABAT,UBASH3B,PRKCD |
| 4.282e-02 | -3.15 | MODULE_485 | MSigDB lists | MODULE_485 | 48 | 3 | 17377 | 282 |
ARL2,SLC40A1,NT5DC2 |
| 4.282e-02 | -3.15 | TAVOR_CEBPA_TARGETS_UP | MSigDB lists | TAVOR_CEBPA_TARGETS_UP | 48 | 3 | 17377 | 282 |
KIAA0513,ACSL1,BIK |
| 4.282e-02 | -3.15 | PARK_APL_PATHOGENESIS_DN | MSigDB lists | PARK_APL_PATHOGENESIS_DN | 48 | 3 | 17377 | 282 |
QSOX1,CEBPA,PRKCA |
| 4.282e-02 | -3.15 | GO_POSITIVE_REGULATION_OF_INTRINSIC_APOPTOTIC_SIGNALING_PATHWAY | MSigDB lists | GO_POSITIVE_REGULATION_OF_INTRINSIC_APOPTOTIC_SIGNALING_PATHWAY | 48 | 3 | 17377 | 282 |
MSX1,PMAIP1,DDIT3 |
| 4.282e-02 | -3.15 | GO_CARDIAC_SEPTUM_MORPHOGENESIS | MSigDB lists | GO_CARDIAC_SEPTUM_MORPHOGENESIS | 48 | 3 | 17377 | 282 |
WNT11,ACVR1,SAV1 |
| 4.282e-02 | -3.15 | SU_PANCREAS | MSigDB lists | SU_PANCREAS | 48 | 3 | 17377 | 282 |
PRDM1,RUNX2,EXOC6B |
| 4.282e-02 | -3.15 | GTAAACC,MIR-299-5P | MSigDB lists | GTAAACC,MIR-299-5P | 48 | 3 | 17377 | 282 |
SGK1,DLX2,HSPA2 |
| 4.282e-02 | -3.15 | BROWNE_HCMV_INFECTION_2HR_DN | MSigDB lists | BROWNE_HCMV_INFECTION_2HR_DN | 48 | 3 | 17377 | 282 |
SGK1,CYP2J2,MYC |
| 4.286e-02 | -3.15 | cardiac ventricle development | biological process | GO:0003231 | 122 | 5 | 17256 | 270 |
SCN5A,WNT11,PRDM1,ACVR1,SAV1 |
| 4.286e-02 | -3.15 | regulation of fat cell differentiation | biological process | GO:0045598 | 122 | 5 | 17256 | 270 |
TRIB3,CEBPA,SAV1,DDIT3,WWTR1 |
| 4.286e-02 | -3.15 | determination of bilateral symmetry | biological process | GO:0009855 | 122 | 5 | 17256 | 270 |
DISP1,ACVR2B,OVOL2,ACVR1,DNAH5 |
| 4.286e-02 | -3.15 | positive regulation of proteolysis involved in cellular protein catabolic process | biological process | GO:1903052 | 122 | 5 | 17256 | 270 |
LONRF1,TRIB3,DAB2IP,CEBPA,PLK2 |
| 4.295e-02 | -3.15 | APBA1 (amyloid beta precursor protein binding family A member 1) | protein interactions | 320 | 20 | 2 | 17029 | 283 |
APBA2,STXBP1 |
| 4.295e-02 | -3.15 | KIR3DL2 (killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 2) | protein interactions | 3812 | 20 | 2 | 17029 | 283 |
ACVR2B,PLXNA2 |
| 4.295e-02 | -3.15 | PDK2 (pyruvate dehydrogenase kinase 2) | protein interactions | 5164 | 20 | 2 | 17029 | 283 |
SGK1,PDK1 |
| 4.295e-02 | -3.15 | DUSP18 (dual specificity phosphatase 18) | protein interactions | 150290 | 20 | 2 | 17029 | 283 |
EPHB6,PTPN6 |
| 4.295e-02 | -3.15 | RGS19 (regulator of G protein signaling 19) | protein interactions | 10287 | 20 | 2 | 17029 | 283 |
PRKCA,GNAO1 |
| 4.295e-02 | -3.15 | TAOK2 (TAO kinase 2) | protein interactions | 9344 | 20 | 2 | 17029 | 283 |
MAP2K6,SLC39A8 |
| 4.295e-02 | -3.15 | GRM5 (glutamate metabotropic receptor 5) | protein interactions | 2915 | 20 | 2 | 17029 | 283 |
PRKCA,PRKCD |
| 4.295e-02 | -3.15 | BMP2 (bone morphogenetic protein 2) | protein interactions | 650 | 20 | 2 | 17029 | 283 |
ACVR2B,ACVR1 |
| 4.295e-02 | -3.15 | CEACAM1 (carcinoembryonic antigen related cell adhesion molecule 1) | protein interactions | 634 | 20 | 2 | 17029 | 283 |
PXN,PTPN6 |
| 4.295e-02 | -3.15 | GPC3 (glypican 3) | protein interactions | 2719 | 20 | 2 | 17029 | 283 |
NRN1,MOXD1 |
| 4.295e-02 | -3.15 | IQGAP2 (IQ motif containing GTPase activating protein 2) | protein interactions | 10788 | 20 | 2 | 17029 | 283 |
TSHR,MYC |
| 4.295e-02 | -3.15 | EPHB1 (EPH receptor B1) | protein interactions | 2047 | 20 | 2 | 17029 | 283 |
EPHB6,PXN |
| 4.295e-02 | -3.15 | HSD17B14 (hydroxysteroid 17-beta dehydrogenase 14) | protein interactions | 51171 | 20 | 2 | 17029 | 283 |
ABAT,DDIT3 |
| 4.306e-02 | -3.15 | GO_REGULATION_OF_CALCIUM_ION_TRANSPORT | MSigDB lists | GO_REGULATION_OF_CALCIUM_ION_TRANSPORT | 198 | 7 | 17377 | 282 |
PDE4D,CACNB4,HSPA2,UBASH3B,GNAO1,PTPN6,WFS1 |
| 4.307e-02 | -3.14 | response to antibiotic | biological process | GO:0046677 | 295 | 9 | 17256 | 270 |
UROS,GNAO1,PRKCD,ADCY1,BNIP3,MAPK13,PLEKHA1,ABAT,ITPR2 |
| 4.307e-02 | -3.14 | LPIN3 (lipin 3) | protein interactions | 64900 | 47 | 3 | 17029 | 283 |
RALGPS2,RASAL2,TANC2 |
| 4.307e-02 | -3.14 | PLD1 (phospholipase D1) | protein interactions | 5337 | 47 | 3 | 17029 | 283 |
PRKCA,APBA2,STXBP1 |
| 4.312e-02 | -3.14 | GSE35825_UNTREATED_VS_IFNA_STIM_MACROPHAGE_DN | MSigDB lists | GSE35825_UNTREATED_VS_IFNA_STIM_MACROPHAGE_DN | 157 | 6 | 17377 | 282 |
P4HA1,TNFSF15,ACVR1,SLC30A4,SAV1,STXBP1 |
| 4.322e-02 | -3.14 | GEORGES_TARGETS_OF_MIR192_AND_MIR215 | MSigDB lists | GEORGES_TARGETS_OF_MIR192_AND_MIR215 | 814 | 20 | 17377 | 282 |
MXI1,ACSL1,KLHL23,FBXO4,SLC39A8,UBASH3B,CYP4V2,SPATA13,KIF5C,SATB2,ACVR2B,GPR137C,EPDR1,TRIB3,KCTD15,LMLN,ZIC5,ZDHHC23,NCEH1,HSPA2 |
| 4.332e-02 | -3.14 | GSE13522_CTRL_VS_T_CRUZI_Y_STRAIN_INF_SKIN_BALBC_MOUSE_DN | MSigDB lists | GSE13522_CTRL_VS_T_CRUZI_Y_STRAIN_INF_SKIN_BALBC_MOUSE_DN | 118 | 5 | 17377 | 282 |
DYRK1B,EPHB6,SATB1,DLX6,RERE |
| 4.332e-02 | -3.14 | KARLSSON_TGFB1_TARGETS_UP | MSigDB lists | KARLSSON_TGFB1_TARGETS_UP | 118 | 5 | 17377 | 282 |
ARHGAP26,LMLN,PLK2,MYC,GTF2F2 |
| 4.332e-02 | -3.14 | hexose catabolic process | biological process | GO:0019320 | 50 | 3 | 17256 | 270 |
GAPDH,ALDOA,HK2 |
| 4.337e-02 | -3.14 | positive regulation of cellular component organization | biological process | GO:0051130 | 1166 | 26 | 17256 | 270 |
EPB41L5,PHLDB2,BDNF,PXN,MSX1,DOCK1,C4A,FBXO4,DSTN,BIK,PLXNA2,ARL2,SLX1B,WNT11,GAS6,PFN2,TLR6,CBLN1,PPM1E,PMAIP1,PRKCD,GTF2F2,HK2,DAB2IP,BNIP3,COBL |
| 4.345e-02 | -3.14 | Wnt Signaling Pathway | WikiPathways | WP428 | 70 | 4 | 5312 | 101 |
WNT11,PRKCA,MYC,PRKCD |
| 4.359e-02 | -3.13 | GO_PROTEIN_CATABOLIC_PROCESS | MSigDB lists | GO_PROTEIN_CATABOLIC_PROCESS | 566 | 15 | 17377 | 282 |
PRSS16,PMAIP1,KLHL3,FBXO4,BACE1,WFS1,WWTR1,GAN,BNIP3L,BNIP3,DAB2IP,PJA1,HERC6,RNF122,DDIT3 |
| 4.371e-02 | -3.13 | focal adhesion | cellular component | GO:0005925 | 397 | 11 | 18223 | 280 |
ARHGAP26,EPB41L5,PHLDB2,LMLN,PXN,EHD3,CAPN5,ARL2,TNS1,PALLD,TLN2 |
| 4.390e-02 | -3.13 | DAG/PE-bd | interpro domains | IPR020454 | 21 | 2 | 18492 | 296 |
PRKCA,PRKCD |
| 4.393e-02 | -3.13 | GO_NEGATIVE_REGULATION_OF_DEVELOPMENTAL_PROCESS | MSigDB lists | GO_NEGATIVE_REGULATION_OF_DEVELOPMENTAL_PROCESS | 765 | 19 | 17377 | 282 |
PHLDB2,MSX1,UBASH3B,WWC1,MAFB,CHADL,WNT11,OVOL2,GAS6,SAV1,TRIB3,MYC,PLK2,WWTR1,BNIP3,DAB2IP,DLX2,GPR161,DDIT3 |
| 4.398e-02 | -3.12 | brain development | biological process | GO:0007420 | 690 | 17 | 17256 | 270 |
KDM7A,NUMBL,SCN5A,MSX1,GNAO1,ADCY1,PLXNA2,NLGN4X,NDRG2,MAFB,BNIP3,SATB2,DAB2IP,DLX2,ABAT,CBLN1,RERE |
| 4.412e-02 | -3.12 | HOMEOBOX | prints domains | PR00024 | 89 | 4 | 4652 | 70 |
MSX1,DLX2,BARX1,DLX6 |
| 4.412e-02 | -3.12 | regulation of secretion | biological process | GO:0051046 | 742 | 18 | 17256 | 270 |
GAPDH,LGR4,ARL2,ITPR2,GAS6,ABAT,PRKCA,PFN2,TLR6,NCS1,GPLD1,FGR,KMO,MAP2K6,SGK1,DISP1,RAB27B,STXBP1 |
| 4.413e-02 | -3.12 | specification of symmetry | biological process | GO:0009799 | 123 | 5 | 17256 | 270 |
DISP1,ACVR2B,OVOL2,ACVR1,DNAH5 |
| 4.413e-02 | -3.12 | osteoblast differentiation | biological process | GO:0001649 | 123 | 5 | 17256 | 270 |
SATB2,WNT11,RUNX2,LGR4,WWTR1 |
| 4.413e-02 | -3.12 | cellular response to reactive oxygen species | biological process | GO:0034614 | 123 | 5 | 17256 | 270 |
MAPK13,BNIP3,PXN,PLEKHA1,PRKCD |
| 4.416e-02 | -3.12 | lung-carcinoma-adenocarcinoma | COSMIC cancer mutations | lung-carcinoma-adenocarcinoma | 15601 | 261 | 17385 | 281 |
ARHGAP26,ACVR1,DUSP8,LGR4,RECK,LSM11,ALG1L,CEBPA,PRKCA,ABHD6,NCS1,EPDR1,PMAIP1,CFHR1,TSHR,TBC1D8,KLHL23,KLHL3,WISP3,EXOC6B,DSTN,BNIP3L,SLC25A28,ABCC2,TNS1,ACVR2B,SAV1,SPATA9,PLK2,RASGRF2,ALDOA,ARHGAP28,MAPK13,TMOD2,TANC2,SCN5A,TMEM63C,ZHX3,CYP2J2,SLC36A4,TNFRSF10C,DYNC1I1,HPCAL4,NIPSNAP3B,MTUS1,RALGPS2,MYC,ZIC5,SRGAP1,MOXD1,STXBP1,GPR161,EPB41L5,BDNF,QSOX1,SHISA2,ARRDC4,OR11H4,ZNF558,ADAMTS3,ISM1,LRRIQ3,QPCTL,EMILIN2,CLMN,IQSEC2,SMYD3,ZNF516,RASAL2,ST14,CCDC110,PLXNA2,COLEC10,TIAM2,TMEM53,ZNF827,KMO,DACT1,DAB2IP,PJA1,PDE4D,RAB27B,DNAH5,ATP6AP1L,C3orf67,DZANK1,GAPDH,PDK1,SOX21,CYB5R2,SFXN4,ADCY1,NLGN4X,SATB2,WNT11,RAB38,TBC1D16,IQCK,WFS1,WWTR1,PLEKHG1,P4HA1,TNFSF15,KLHL31,COBL,KCTD1,CCDC148,MXI1,TMEM132C,BACE1,BIK,CCNJL,KIF5C,ARL2,GAS6,ZNF219,NEO1,RGS17,GPR155,SMPDL3A,PARP9,TMC7,MN1,SLC40A1,PXN,MPP1,GPR137C,GPLD1,TRIB3,FGR,GNAO1,MYOM2,TNFRSF17,DDIT3,B4GALT7,PHC1,ACSL1,HEBP1,PTPN21,NDRG2,NRN1,ABAT,ITPR2,SLC2A13,CACNB4,ABHD4,HMCN1,EPCAM,PPM1E,FKBP9,CPNE2,MARVELD2,DLX6,TMEM143,TLN2,FANK1,OR2W3,ZNF391,PGBD5,PNRC1,CAPN5,TTC22,PLEKHA1,SGK2,PLEKHB1,NT5DC2,DYRK1B,SPNS1,TCF7L1,ERN1,DLX2,APBA2,GPR63,LONRF1,RGS16,RUNX2,ZNF395,BVES,FBXO4,UBASH3B,CYP4V2,ATP6V1E2,RASL11B,SETBP1,CHADL,SATB1,PFN2,FHOD3,NUMBL,SLC30A4,GAN,EBF4,BNIP3,NCEH1,VGLL4,IL17RD,SPATA13,EFNA3,MAFB,STRADB,WWC1,WDR25,PPFIA4,LHPP,PRDM1,B4GALNT3,KIAA0355,HK2,RNF122,DOCK1,RHPN2,FAM198B,KIF21B,RADIL,CBLN1,KCTD15,RPS6KL1,EEPD1,ZDHHC23,ZNF521,MAP7,MYH15,TMEM120B,HSPA2,FAM78B,PHLDB2,UROS,PTPN6,SLC39A8,JAM3,CENPV,IFT81,LMLN,ANKRD31,DISP1,NECAB2,PRSS16,ARHGEF11,BLVRB,RASD2,EHD3,PRKCD,SGK1,PRICKLE2,TRIM3,CCDC122,ACTA2,MSX1,NUAK2,OGDHL,EXOG,PALLD,TLR6,CTIF,RERE,FMO4,MAP2K6,KIAA0513,ZNF474,RNF157,PKIA |
| 4.432e-02 | -3.12 | DANG_REGULATED_BY_MYC_DN | MSigDB lists | DANG_REGULATED_BY_MYC_DN | 242 | 8 | 17377 | 282 |
BDNF,ACSL1,SCAMP1,PMAIP1,MYC,WFS1,CEBPA,DDIT3 |
| 4.435e-02 | -3.12 | positive regulation of proteasomal ubiquitin-dependent protein catabolic process | biological process | GO:0032436 | 85 | 4 | 17256 | 270 |
LONRF1,TRIB3,CEBPA,PLK2 |
| 4.440e-02 | -3.11 | GO_CARDIAC_SEPTUM_DEVELOPMENT | MSigDB lists | GO_CARDIAC_SEPTUM_DEVELOPMENT | 82 | 4 | 17377 | 282 |
WNT11,PRDM1,ACVR1,SAV1 |
| 4.440e-02 | -3.11 | sperm principal piece | cellular component | GO:0097228 | 22 | 2 | 18223 | 280 |
IFT81,CATSPERE |
| 4.440e-02 | -3.11 | myosin filament | cellular component | GO:0032982 | 22 | 2 | 18223 | 280 |
MYH15,MYOM2 |
| 4.448e-02 | -3.11 | INSP3RECEPTR | prints domains | PR00779 | 3 | 1 | 4652 | 70 |
ITPR2 |
| 4.448e-02 | -3.11 | PROFILINMAML | prints domains | PR01639 | 3 | 1 | 4652 | 70 |
PFN2 |
| 4.448e-02 | -3.11 | LEUZIPPRMYC | prints domains | PR00044 | 3 | 1 | 4652 | 70 |
MYC |
| 4.448e-02 | -3.11 | ONCOGENEAML1 | prints domains | PR00967 | 3 | 1 | 4652 | 70 |
RUNX2 |
| 4.448e-02 | -3.11 | COFILIN | prints domains | PR00006 | 3 | 1 | 4652 | 70 |
DSTN |
| 4.448e-02 | -3.11 | ATP-dependent microtubule motor activity | molecular function | GO:1990939 | 49 | 3 | 17224 | 278 |
KIF5C,DYNC1I1,DNAH5 |
| 4.456e-02 | -3.11 | proton-transporting ATPase activity, rotational mechanism | molecular function | GO:0046961 | 21 | 2 | 17224 | 278 |
ATP6V1E2,ATP6AP1L |
| 4.456e-02 | -3.11 | glucose transmembrane transporter activity | molecular function | GO:0005355 | 21 | 2 | 17224 | 278 |
MFSD4A,SLC2A13 |
| 4.457e-02 | -3.11 | positive regulation of kinase activity | biological process | GO:0033674 | 589 | 15 | 17256 | 270 |
FGR,ACSL1,MAP2K6,PRKCD,ERN1,ADCY1,STRADB,INAVA,TNFSF15,DAB2IP,WNT11,GAS6,ACVR2B,EPHB6,TLR6 |
| 4.465e-02 | -3.11 | GSE40274_FOXP3_VS_FOXP3_AND_SATB1_TRANSDUCED_ACTIVATED_CD4_TCELL_UP | MSigDB lists | GSE40274_FOXP3_VS_FOXP3_AND_SATB1_TRANSDUCED_ACTIVATED_CD4_TCELL_UP | 119 | 5 | 17377 | 282 |
MAPK13,TNS1,SLC40A1,FGR,ADAMTS3 |
| 4.467e-02 | -3.11 | haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-myelodysplastic_syndrome_therapy_related | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-myelodysplastic_syndrome_therapy_related | 21 | 2 | 17385 | 281 |
SETBP1,CEBPA |
| 4.467e-02 | -3.11 | myelodysplastic_syndrome_therapy_related | COSMIC cancer mutations | myelodysplastic_syndrome_therapy_related | 21 | 2 | 17385 | 281 |
SETBP1,CEBPA |
| 4.472e-02 | -3.11 | Glycerol Phosphate Shuttle | SMPDB pathways | SMP00124 | 3 | 1 | 992 | 15 |
GAPDH |
| 4.474e-02 | -3.11 | post-translational protein modification | biological process | GO:0043687 | 440 | 12 | 17256 | 270 |
ENAM,QSOX1,KLHL3,RECK,C4A,FBXO4,WFS1,GAN,NRN1,GAS6,RAB38,GPLD1 |
| 4.475e-02 | -3.11 | Signaling by PDGF | REACTOME pathways | R-HSA-186797 | 376 | 10 | 10287 | 148 |
IL17RD,TRIB3,RASAL2,DUSP8,RASGRF2,PRKCD,ADCY1,DAB2IP,ITPR2,PRKCA |
| 4.500e-02 | -3.10 | GO_NEGATIVE_REGULATION_OF_ORGAN_GROWTH | MSigDB lists | GO_NEGATIVE_REGULATION_OF_ORGAN_GROWTH | 21 | 2 | 17377 | 282 |
WWC1,SAV1 |
| 4.500e-02 | -3.10 | HUI_MAPK14_TARGETS_UP | MSigDB lists | HUI_MAPK14_TARGETS_UP | 21 | 2 | 17377 | 282 |
DUSP8,MAP2K6 |
| 4.500e-02 | -3.10 | WANG_NEOPLASTIC_TRANSFORMATION_BY_CCND1_MYC | MSigDB lists | WANG_NEOPLASTIC_TRANSFORMATION_BY_CCND1_MYC | 21 | 2 | 17377 | 282 |
TRIB3,DDIT3 |
| 4.500e-02 | -3.10 | chr2q23 | MSigDB lists | chr2q23 | 21 | 2 | 17377 | 282 |
KIF5C,ACVR1 |
| 4.500e-02 | -3.10 | GO_HYDROGEN_EXPORTING_ATPASE_ACTIVITY | MSigDB lists | GO_HYDROGEN_EXPORTING_ATPASE_ACTIVITY | 21 | 2 | 17377 | 282 |
ATP6V1E2,ATP6AP1L |
| 4.500e-02 | -3.10 | GO_POSITIVE_REGULATION_OF_PROTEIN_COMPLEX_DISASSEMBLY | MSigDB lists | GO_POSITIVE_REGULATION_OF_PROTEIN_COMPLEX_DISASSEMBLY | 21 | 2 | 17377 | 282 |
BNIP3,DSTN |
| 4.500e-02 | -3.10 | STEGER_ADIPOGENESIS_UP | MSigDB lists | STEGER_ADIPOGENESIS_UP | 21 | 2 | 17377 | 282 |
CEBPA,ACSL1 |
| 4.500e-02 | -3.10 | MACLACHLAN_BRCA1_TARGETS_UP | MSigDB lists | MACLACHLAN_BRCA1_TARGETS_UP | 21 | 2 | 17377 | 282 |
GAPDH,DDIT3 |
| 4.504e-02 | -3.10 | HALLMARK_ESTROGEN_RESPONSE_LATE | MSigDB lists | HALLMARK_ESTROGEN_RESPONSE_LATE | 200 | 7 | 17377 | 282 |
SGK1,MAPK13,OVOL2,ST14,PTPN6,WFS1,BLVRB |
| 4.507e-02 | -3.10 | CTTTGA_V$LEF1_Q2 | MSigDB lists | CTTTGA_V$LEF1_Q2 | 1128 | 26 | 17377 | 282 |
ENAM,MSX1,GAPDH,RASAL2,SLC39A8,SOX21,BACE1,BNIP3L,SLC25A28,PRDM1,OVOL2,SATB1,HMCN1,NEO1,RERE,ZNF827,KCTD15,RALGPS2,MAP2K6,EEPD1,ZNF521,DAB2IP,TNFRSF17,VGLL4,PHC1,TBC1D8 |
| 4.508e-02 | -3.10 | GO_HOMOTYPIC_CELL_CELL_ADHESION | MSigDB lists | GO_HOMOTYPIC_CELL_CELL_ADHESION | 49 | 3 | 17377 | 282 |
GAS6,STXBP1,PTPN6 |
| 4.508e-02 | -3.10 | PID_PI3KCI_PATHWAY | MSigDB lists | PID_PI3KCI_PATHWAY | 49 | 3 | 17377 | 282 |
SGK1,FGR,PLEKHA1 |
| 4.508e-02 | -3.10 | CAGTCAC,MIR-134 | MSigDB lists | CAGTCAC,MIR-134 | 49 | 3 | 17377 | 282 |
ACSL1,VGLL4,GNAO1 |
| 4.511e-02 | -3.10 | calcium channel activity | molecular function | GO:0005262 | 120 | 5 | 17224 | 278 |
ITPR2,GAS6,TMEM37,CACNB4,NCS1 |
| 4.521e-02 | -3.10 | V$ERR1_Q2 | MSigDB lists | V$ERR1_Q2 | 243 | 8 | 17377 | 282 |
PPM1E,SCN5A,GAPDH,ADCY1,NDRG2,WWC1,ABAT,SATB1 |
| 4.532e-02 | -3.09 | transmembrane receptor protein kinase activity | molecular function | GO:0019199 | 83 | 4 | 17224 | 278 |
EPHB6,ACVR2B,ACVR1,EFNA3 |
| 4.538e-02 | -3.09 | GSE40274_CTRL_VS_LEF1_TRANSDUCED_ACTIVATED_CD4_TCELL_DN | MSigDB lists | GSE40274_CTRL_VS_LEF1_TRANSDUCED_ACTIVATED_CD4_TCELL_DN | 159 | 6 | 17377 | 282 |
MN1,UROS,RNF157,TMEM120B,ABHD6,NCS1 |
| 4.538e-02 | -3.09 | GCNP_SHH_UP_EARLY.V1_DN | MSigDB lists | GCNP_SHH_UP_EARLY.V1_DN | 159 | 6 | 17377 | 282 |
PHLDB2,DBP,UROS,PLK2,JAM3,EEPD1 |
| 4.539e-02 | -3.09 | mitochondrial pyruvate dehydrogenase complex | cellular component | GO:0005967 | 3 | 1 | 18223 | 280 |
PDK1 |
| 4.539e-02 | -3.09 | smooth muscle contractile fiber | cellular component | GO:0030485 | 3 | 1 | 18223 | 280 |
ACTA2 |
| 4.539e-02 | -3.09 | ciliary pocket membrane | cellular component | GO:0020018 | 3 | 1 | 18223 | 280 |
EHD3 |
| 4.539e-02 | -3.09 | alphav-beta3 integrin-PKCalpha complex | cellular component | GO:0035866 | 3 | 1 | 18223 | 280 |
PRKCA |
| 4.539e-02 | -3.09 | ciliary pocket | cellular component | GO:0020016 | 3 | 1 | 18223 | 280 |
EHD3 |
| 4.539e-02 | -3.09 | activin receptor complex | cellular component | GO:0048179 | 3 | 1 | 18223 | 280 |
ACVR1 |
| 4.539e-02 | -3.09 | Slx1-Slx4 complex | cellular component | GO:0033557 | 3 | 1 | 18223 | 280 |
SLX1B |
| 4.540e-02 | -3.09 | ARHGEF7 (Rho guanine nucleotide exchange factor 7) | protein interactions | 8874 | 48 | 3 | 17029 | 283 |
INAVA,PPM1E,PXN |
| 4.540e-02 | -3.09 | UBE2L6 (ubiquitin conjugating enzyme E2 L6) | protein interactions | 9246 | 48 | 3 | 17029 | 283 |
LONRF1,HERC6,RNF122 |
| 4.543e-02 | -3.09 | human chr14q22.1 | chromosome location | human chr14q22.1 | 27 | 2 | 26185 | 331 |
SAV1,GPR137C |
| 4.550e-02 | -3.09 | regulation of macroautophagy | biological process | GO:0016241 | 165 | 6 | 17256 | 270 |
ATP6V1E2,QSOX1,BNIP3,GAPDH,ERN1,BNIP3L |
| 4.551e-02 | -3.09 | lymphocyte homeostasis | biological process | GO:0002260 | 51 | 3 | 17256 | 270 |
SLC40A1,TNFRSF17,PMAIP1 |
| 4.558e-02 | -3.09 | Integrin-mediated Cell Adhesion | WikiPathways | WP185 | 103 | 5 | 5312 | 101 |
TNS1,PXN,DOCK1,MAP2K6,CAPN5 |
| 4.559e-02 | -3.09 | GO_CELL_DEATH | MSigDB lists | GO_CELL_DEATH | 973 | 23 | 17377 | 282 |
GAPDH,PDK1,DOCK1,PTPN6,BIK,NUAK2,BNIP3L,TNFRSF10C,GAS6,PRKCA,SATB1,TRIB3,PMAIP1,MAP2K6,MYC,ERN1,PRKCD,HK2,SGK1,DAB2IP,TNFSF15,BNIP3,DDIT3 |
| 4.560e-02 | -3.09 | human chr6q21 | chromosome location | human chr6q21 | 63 | 3 | 26185 | 331 |
PRDM1,WISP3,BVES |
| 4.569e-02 | -3.09 | cell-substrate adherens junction | cellular component | GO:0005924 | 400 | 11 | 18223 | 280 |
ARHGAP26,EPB41L5,PHLDB2,LMLN,PXN,EHD3,CAPN5,ARL2,TNS1,PALLD,TLN2 |
| 4.571e-02 | -3.09 | LYPD3 (LY6/PLAUR domain containing 3) | protein interactions | 27076 | 117 | 5 | 17029 | 283 |
QSOX1,NCEH1,SCAMP1,WFS1,MYORG |
| 4.576e-02 | -3.08 | PSMA3 (proteasome subunit alpha 3) | protein interactions | 5684 | 281 | 9 | 17029 | 283 |
TRIB3,NUMBL,GAPDH,MYC,ALDOA,SLX1B,TBC1D16,HSPA2,RERE |
| 4.583e-02 | -3.08 | basolateral plasma membrane | cellular component | GO:0016323 | 212 | 7 | 18223 | 280 |
MAP7,EPCAM,SLC40A1,DISP1,TSHR,ST14,MARVELD2 |
| 4.584e-02 | -3.08 | FERM_2 | interpro domains | IPR035963 | 50 | 3 | 18492 | 296 |
EPB41L5,TLN2,PTPN21 |
| 4.587e-02 | -3.08 | cytokine production involved in immune response | biological process | GO:0002367 | 22 | 2 | 17256 | 270 |
INAVA,GAS6 |
| 4.587e-02 | -3.08 | negative regulation of neurological system process | biological process | GO:0031645 | 22 | 2 | 17256 | 270 |
NLGN4X,CBLN1 |
| 4.587e-02 | -3.08 | negative regulation of stress fiber assembly | biological process | GO:0051497 | 22 | 2 | 17256 | 270 |
ARHGAP28,PHLDB2 |
| 4.587e-02 | -3.08 | positive regulation of myeloid leukocyte mediated immunity | biological process | GO:0002888 | 22 | 2 | 17256 | 270 |
FGR,STXBP1 |
| 4.595e-02 | -3.08 | GIT1 (GIT ArfGAP 1) | protein interactions | 28964 | 81 | 4 | 17029 | 283 |
PPFIA4,TRIB3,PXN,GRK3 |
| 4.597e-02 | -3.08 | regulation of membrane permeability | biological process | GO:0090559 | 86 | 4 | 17256 | 270 |
BNIP3,PMAIP1,BNIP3L,HK2 |
| 4.599e-02 | -3.08 | TACTTGA,MIR-26A,MIR-26B | MSigDB lists | TACTTGA,MIR-26A,MIR-26B | 288 | 9 | 17377 | 282 |
PHLDB2,MXI1,PNRC1,LGR4,LSM11,PRKCD,SRGAP1,STRADB,NCEH1 |
| 4.600e-02 | -3.08 | VERHAAK_GLIOBLASTOMA_NEURAL | MSigDB lists | VERHAAK_GLIOBLASTOMA_NEURAL | 120 | 5 | 17377 | 282 |
NDRG2,UROS,DYNC1I1,HPCAL4,PGBD5 |
| 4.600e-02 | -3.08 | RODRIGUES_DCC_TARGETS_DN | MSigDB lists | RODRIGUES_DCC_TARGETS_DN | 120 | 5 | 17377 | 282 |
ABAT,RUNX2,BACE1,BIK,CYP4V2 |
| 4.608e-02 | -3.08 | HOEBEKE_LYMPHOID_STEM_CELL_DN | MSigDB lists | HOEBEKE_LYMPHOID_STEM_CELL_DN | 83 | 4 | 17377 | 282 |
TNS1,RAB38,PMAIP1,SLC39A8 |
| 4.608e-02 | -3.08 | GO_EMBRYONIC_PLACENTA_DEVELOPMENT | MSigDB lists | GO_EMBRYONIC_PLACENTA_DEVELOPMENT | 83 | 4 | 17377 | 282 |
CEBPA,PRDM1,OVOL2,ST14 |
| 4.612e-02 | -3.08 | V$NFKB_Q6 | MSigDB lists | V$NFKB_Q6 | 244 | 8 | 17377 | 282 |
BDNF,SCAMP1,GNAO1,PRKCD,ERN1,NDRG2,TNFSF15,SATB1 |
| 4.615e-02 | -3.08 | Glutamate Neurotransmitter Release Cycle | REACTOME pathways | R-HSA-210500 | 24 | 2 | 10287 | 148 |
PPFIA4,STXBP1 |
| 4.616e-02 | -3.08 | cellular protein metabolic process | biological process | GO:0044267 | 3771 | 71 | 17256 | 270 |
CCDC126,ACVR1,DUSP8,RASAL2,RECK,C4A,PTPN21,ALG1L,NRN1,PRKCA,FKBP9,PPM1E,PMAIP1,RPS6KL1,ZDHHC23,DAB2IP,PJA1,EPHB6,GAPDH,PDK1,KLHL23,KLHL3,PTPN6,BNIP3L,WNT11,ACVR2B,RAB38,SGK2,GRK3,DYRK1B,RASGRF2,PLK2,WFS1,ERN1,WWTR1,P4HA1,MAPK13,KLHL31,LONRF1,UBASH3B,FBXO4,BACE1,GAS6,HERC6,SATB1,KDM7A,MYC,PRKCD,GAN,SGK1,TRIM3,BNIP3,PARP9,IL17RD,QSOX1,ENAM,B3GLCT,NUAK2,STRADB,LHPP,ARRDC4,GPLD1,TRIB3,FGR,MAP2K6,QPCTL,RNF122,SMYD3,DDIT3,B4GALT7,PHC1 |
| 4.619e-02 | -3.08 | FERM_3 | prosite domains | PS50057 | 48 | 3 | 12060 | 202 |
EPB41L5,TLN2,PTPN21 |
| 4.620e-02 | -3.07 | sequence-specific double-stranded DNA binding | molecular function | GO:1990837 | 774 | 19 | 17224 | 278 |
RUNX2,MSX1,MXI1,ZNF516,ZNF395,ZHX3,SOX21,MAFB,CEBPA,SATB2,PRDM1,ZNF219,SATB1,MYC,DLX2,DBP,SMYD3,BARX1,DDIT3 |
| 4.621e-02 | -3.07 | negative regulation of dopamine secretion | biological process | GO:0033602 | 3 | 1 | 17256 | 270 |
ABAT |
| 4.621e-02 | -3.07 | activation of meiosis | biological process | GO:0090427 | 3 | 1 | 17256 | 270 |
MSX1 |
| 4.621e-02 | -3.07 | regulation of high-density lipoprotein particle clearance | biological process | GO:0010982 | 3 | 1 | 17256 | 270 |
GPLD1 |
| 4.621e-02 | -3.07 | response to platinum ion | biological process | GO:0070541 | 3 | 1 | 17256 | 270 |
UROS |
| 4.621e-02 | -3.07 | mesoderm migration involved in gastrulation | biological process | GO:0007509 | 3 | 1 | 17256 | 270 |
EPB41L5 |
| 4.621e-02 | -3.07 | octopamine biosynthetic process | biological process | GO:0006589 | 3 | 1 | 17256 | 270 |
MOXD1 |
| 4.621e-02 | -3.07 | embryonic nail plate morphogenesis | biological process | GO:0035880 | 3 | 1 | 17256 | 270 |
MSX1 |
| 4.621e-02 | -3.07 | sinoatrial node development | biological process | GO:0003163 | 3 | 1 | 17256 | 270 |
BVES |
| 4.621e-02 | -3.07 | regulation of amacrine cell differentiation | biological process | GO:1902869 | 3 | 1 | 17256 | 270 |
DLX2 |
| 4.621e-02 | -3.07 | intracellular copper ion transport | biological process | GO:0015680 | 3 | 1 | 17256 | 270 |
ATOX1 |
| 4.621e-02 | -3.07 | hindbrain tangential cell migration | biological process | GO:0021934 | 3 | 1 | 17256 | 270 |
PLXNA2 |
| 4.621e-02 | -3.07 | regulation of Ral protein signal transduction | biological process | GO:0032485 | 3 | 1 | 17256 | 270 |
RALGPS2 |
| 4.621e-02 | -3.07 | cerebellum maturation | biological process | GO:0021590 | 3 | 1 | 17256 | 270 |
RERE |
| 4.621e-02 | -3.07 | negative regulation of filopodium assembly | biological process | GO:0051490 | 3 | 1 | 17256 | 270 |
PRKCD |
| 4.621e-02 | -3.07 | synaptic signaling via neuropeptide | biological process | GO:0099538 | 3 | 1 | 17256 | 270 |
BDNF |
| 4.621e-02 | -3.07 | cerebellar cortex maturation | biological process | GO:0021699 | 3 | 1 | 17256 | 270 |
RERE |
| 4.621e-02 | -3.07 | distal tubule morphogenesis | biological process | GO:0072156 | 3 | 1 | 17256 | 270 |
KLHL3 |
| 4.621e-02 | -3.07 | axon target recognition | biological process | GO:0007412 | 3 | 1 | 17256 | 270 |
STXBP1 |
| 4.621e-02 | -3.07 | regulation of heparan sulfate proteoglycan biosynthetic process | biological process | GO:0010908 | 3 | 1 | 17256 | 270 |
PXYLP1 |
| 4.621e-02 | -3.07 | adenylate cyclase-activating adrenergic receptor signaling pathway involved in regulation of heart rate | biological process | GO:0140200 | 3 | 1 | 17256 | 270 |
PDE4D |
| 4.621e-02 | -3.07 | termination of signal transduction | biological process | GO:0023021 | 3 | 1 | 17256 | 270 |
PRKCD |
| 4.621e-02 | -3.07 | detection of bacterial lipopeptide | biological process | GO:0070340 | 3 | 1 | 17256 | 270 |
TLR6 |
| 4.621e-02 | -3.07 | axial mesoderm morphogenesis | biological process | GO:0048319 | 3 | 1 | 17256 | 270 |
EPB41L5 |
| 4.621e-02 | -3.07 | apical constriction | biological process | GO:0003383 | 3 | 1 | 17256 | 270 |
EPB41L5 |
| 4.621e-02 | -3.07 | quinolinate biosynthetic process | biological process | GO:0019805 | 3 | 1 | 17256 | 270 |
KMO |
| 4.621e-02 | -3.07 | fibroblast apoptotic process | biological process | GO:0044346 | 3 | 1 | 17256 | 270 |
MYC |
| 4.621e-02 | -3.07 | sinoatrial node cell differentiation | biological process | GO:0060921 | 3 | 1 | 17256 | 270 |
BVES |
| 4.621e-02 | -3.07 | tryptophan transport | biological process | GO:0015827 | 3 | 1 | 17256 | 270 |
SLC36A4 |
| 4.621e-02 | -3.07 | positive regulation by organism of programmed cell death in other organism involved in symbiotic interaction | biological process | GO:0052330 | 3 | 1 | 17256 | 270 |
GAPDH |
| 4.621e-02 | -3.07 | positive regulation of proteoglycan biosynthetic process | biological process | GO:1902730 | 3 | 1 | 17256 | 270 |
PXYLP1 |
| 4.621e-02 | -3.07 | epithelial cell differentiation involved in embryonic placenta development | biological process | GO:0060671 | 3 | 1 | 17256 | 270 |
ST14 |
| 4.621e-02 | -3.07 | regulation of synaptic vesicle fusion to presynaptic active zone membrane | biological process | GO:0031630 | 3 | 1 | 17256 | 270 |
STXBP1 |
| 4.621e-02 | -3.07 | substrate-dependent cell migration, cell attachment to substrate | biological process | GO:0006931 | 3 | 1 | 17256 | 270 |
EPB41L5 |
| 4.621e-02 | -3.07 | membrane depolarization during Purkinje myocyte cell action potential | biological process | GO:0086047 | 3 | 1 | 17256 | 270 |
SCN5A |
| 4.621e-02 | -3.07 | regulation of dense core granule biogenesis | biological process | GO:2000705 | 3 | 1 | 17256 | 270 |
PRKCA |
| 4.621e-02 | -3.07 | endocardial cushion fusion | biological process | GO:0003274 | 3 | 1 | 17256 | 270 |
ACVR1 |
| 4.621e-02 | -3.07 | positive regulation of apoptotic process in other organism | biological process | GO:0044533 | 3 | 1 | 17256 | 270 |
GAPDH |
| 4.621e-02 | -3.07 | negative regulation of fibroblast growth factor production | biological process | GO:0090272 | 3 | 1 | 17256 | 270 |
WNT11 |
| 4.621e-02 | -3.07 | vascular endothelial growth factor production | biological process | GO:0010573 | 3 | 1 | 17256 | 270 |
ADAMTS3 |
| 4.621e-02 | -3.07 | cloacal septation | biological process | GO:0060197 | 3 | 1 | 17256 | 270 |
WNT11 |
| 4.621e-02 | -3.07 | embryonic hindgut morphogenesis | biological process | GO:0048619 | 3 | 1 | 17256 | 270 |
DACT1 |
| 4.621e-02 | -3.07 | gamma-aminobutyric acid biosynthetic process | biological process | GO:0009449 | 3 | 1 | 17256 | 270 |
ABAT |
| 4.621e-02 | -3.07 | positive regulation by symbiont of host programmed cell death | biological process | GO:0052042 | 3 | 1 | 17256 | 270 |
GAPDH |
| 4.621e-02 | -3.07 | membrane depolarization during atrial cardiac muscle cell action potential | biological process | GO:0098912 | 3 | 1 | 17256 | 270 |
SCN5A |
| 4.621e-02 | -3.07 | positive regulation of adenosine receptor signaling pathway | biological process | GO:0060168 | 3 | 1 | 17256 | 270 |
NECAB2 |
| 4.621e-02 | -3.07 | positive regulation of heparan sulfate proteoglycan biosynthetic process | biological process | GO:0010909 | 3 | 1 | 17256 | 270 |
PXYLP1 |
| 4.621e-02 | -3.07 | positive regulation of enamel mineralization | biological process | GO:0070175 | 3 | 1 | 17256 | 270 |
ENAM |
| 4.621e-02 | -3.07 | brain segmentation | biological process | GO:0035284 | 3 | 1 | 17256 | 270 |
MAFB |
| 4.621e-02 | -3.07 | positive regulation by organism of apoptotic process in other organism involved in symbiotic interaction | biological process | GO:0052501 | 3 | 1 | 17256 | 270 |
GAPDH |
| 4.621e-02 | -3.07 | membrane depolarization during bundle of His cell action potential | biological process | GO:0086048 | 3 | 1 | 17256 | 270 |
SCN5A |
| 4.621e-02 | -3.07 | Purkinje myocyte action potential | biological process | GO:0086017 | 3 | 1 | 17256 | 270 |
SCN5A |
| 4.621e-02 | -3.07 | central nervous system segmentation | biological process | GO:0035283 | 3 | 1 | 17256 | 270 |
MAFB |
| 4.621e-02 | -3.07 | commitment of multipotent stem cells to neuronal lineage in forebrain | biological process | GO:0021898 | 3 | 1 | 17256 | 270 |
DLX2 |
| 4.621e-02 | -3.07 | positive regulation of prolactin secretion | biological process | GO:1902722 | 3 | 1 | 17256 | 270 |
ABAT |
| 4.621e-02 | -3.07 | epithelial cell morphogenesis involved in placental branching | biological process | GO:0060672 | 3 | 1 | 17256 | 270 |
ST14 |
| 4.621e-02 | -3.07 | regulation of platelet-derived growth factor production | biological process | GO:0090361 | 3 | 1 | 17256 | 270 |
NDRG2 |
| 4.621e-02 | -3.07 | trans-synaptic signaling by neuropeptide, modulating synaptic transmission | biological process | GO:0099551 | 3 | 1 | 17256 | 270 |
BDNF |
| 4.621e-02 | -3.07 | negative regulation of collagen fibril organization | biological process | GO:1904027 | 3 | 1 | 17256 | 270 |
CHADL |
| 4.621e-02 | -3.07 | trans-synaptic signaling by neuropeptide | biological process | GO:0099540 | 3 | 1 | 17256 | 270 |
BDNF |
| 4.621e-02 | -3.07 | octopamine metabolic process | biological process | GO:0046333 | 3 | 1 | 17256 | 270 |
MOXD1 |
| 4.643e-02 | -3.07 | MAPK (p38) signaling | KEGG pathways | hsa_M00689 | 22 | 2 | 7161 | 113 |
MAPK13,MAP2K6 |
| 4.643e-02 | -3.07 | MAPK (p38) signaling | KEGG pathways | M00689 | 22 | 2 | 7161 | 113 |
MAPK13,MAP2K6 |
| 4.651e-02 | -3.07 | transcription regulatory region DNA binding | molecular function | GO:0044212 | 877 | 21 | 17224 | 278 |
RUNX2,MSX1,MXI1,ZNF516,ZNF395,ZHX3,SOX21,MAFB,WNT11,CEBPA,SATB2,PRDM1,ZNF219,SATB1,TCF7L1,MYC,DLX2,DBP,SMYD3,BARX1,DDIT3 |
| 4.654e-02 | -3.07 | GSE45365_NK_CELL_VS_CD8A_DC_MCMV_INFECTION_UP | MSigDB lists | GSE45365_NK_CELL_VS_CD8A_DC_MCMV_INFECTION_UP | 160 | 6 | 17377 | 282 |
SGK1,LONRF1,CHADL,LSM11,LRRIQ3,BIK |
| 4.654e-02 | -3.07 | GSE25087_FETAL_VS_ADULT_TREG_DN | MSigDB lists | GSE25087_FETAL_VS_ADULT_TREG_DN | 160 | 6 | 17377 | 282 |
KIF5C,C2orf88,UBASH3B,BACE1,ERN1,ADCY1 |
| 4.654e-02 | -3.07 | CAIRO_LIVER_DEVELOPMENT_UP | MSigDB lists | CAIRO_LIVER_DEVELOPMENT_UP | 160 | 6 | 17377 | 282 |
KCTD15,SATB1,PFN2,RECK,PLK2,NEO1 |
| 4.654e-02 | -3.07 | GSE9960_GRAM_NEG_VS_GRAM_NEG_AND_POS_SEPSIS_PBMC_UP | MSigDB lists | GSE9960_GRAM_NEG_VS_GRAM_NEG_AND_POS_SEPSIS_PBMC_UP | 160 | 6 | 17377 | 282 |
WWC1,ZNF827,SCN5A,DLX2,COBL,ADCY1 |
| 4.661e-02 | -3.07 | positive regulation of binding | biological process | GO:0051099 | 166 | 6 | 17256 | 270 |
EPB41L5,TRIB3,BDNF,DACT1,PLK2,PARP9 |
| 4.677e-02 | -3.06 | protein kinase A binding | molecular function | GO:0051018 | 50 | 3 | 17224 | 278 |
C2orf88,DACT1,PKIA |
| 4.680e-02 | -3.06 | contractile fiber part | cellular component | GO:0044449 | 213 | 7 | 18223 | 280 |
ACTA2,SCN5A,MYOM2,TMOD2,PALLD,FHOD3,ALDOA |
| 4.685e-02 | -3.06 | GO_ION_TRANSMEMBRANE_TRANSPORT | MSigDB lists | GO_ION_TRANSMEMBRANE_TRANSPORT | 771 | 19 | 17377 | 282 |
SLC40A1,SCN5A,TMEM63C,SLC39A8,SFXN4,ATOX1,ATP6V1E2,SLC36A4,ABCC2,GAS6,ITPR2,SGK2,CACNB4,NCS1,SLC30A4,SGK1,TMEM37,ATP6AP1L,DDIT3 |
| 4.692e-02 | -3.06 | OxoGdeHyase_C | pfam domains | PF16870 | 3 | 1 | 17054 | 271 |
OGDHL |
| 4.692e-02 | -3.06 | AMOP | pfam domains | PF03782 | 3 | 1 | 17054 | 271 |
ISM1 |
| 4.692e-02 | -3.06 | Evr1_Alr | pfam domains | PF04777 | 3 | 1 | 17054 | 271 |
QSOX1 |
| 4.692e-02 | -3.06 | Peptidase_S28 | pfam domains | PF05577 | 3 | 1 | 17054 | 271 |
PRSS16 |
| 4.692e-02 | -3.06 | ABM | pfam domains | PF03992 | 3 | 1 | 17054 | 271 |
NECAB2 |
| 4.692e-02 | -3.06 | PHM7_cyt | pfam domains | PF14703 | 3 | 1 | 17054 | 271 |
TMEM63C |
| 4.692e-02 | -3.06 | Homez | pfam domains | PF11569 | 3 | 1 | 17054 | 271 |
ZHX3 |
| 4.692e-02 | -3.06 | G2F | pfam domains | PF07474 | 3 | 1 | 17054 | 271 |
HMCN1 |
| 4.692e-02 | -3.06 | RSN1_TM | pfam domains | PF13967 | 3 | 1 | 17054 | 271 |
TMEM63C |
| 4.692e-02 | -3.06 | DLL_N | pfam domains | PF12413 | 3 | 1 | 17054 | 271 |
DLX2 |
| 4.692e-02 | -3.06 | Runt | pfam domains | PF00853 | 3 | 1 | 17054 | 271 |
RUNX2 |
| 4.692e-02 | -3.06 | B9-C2 | pfam domains | PF07162 | 3 | 1 | 17054 | 271 |
B9D1 |
| 4.692e-02 | -3.06 | Ribonuc_2-5A | pfam domains | PF06479 | 3 | 1 | 17054 | 271 |
ERN1 |
| 4.692e-02 | -3.06 | PA14 | pfam domains | PF07691 | 3 | 1 | 17054 | 271 |
B4GALNT3 |
| 4.692e-02 | -3.06 | Glycolytic | pfam domains | PF00274 | 3 | 1 | 17054 | 271 |
ALDOA |
| 4.692e-02 | -3.06 | RSN1_7TM | pfam domains | PF02714 | 3 | 1 | 17054 | 271 |
TMEM63C |
| 4.692e-02 | -3.06 | Cu2_monoox_C | pfam domains | PF03712 | 3 | 1 | 17054 | 271 |
MOXD1 |
| 4.692e-02 | -3.06 | DUF667 | pfam domains | PF05018 | 3 | 1 | 17054 | 271 |
C3orf67 |
| 4.692e-02 | -3.06 | FAM131 | pfam domains | PF15010 | 3 | 1 | 17054 | 271 |
FAM131C |
| 4.692e-02 | -3.06 | DUF4482 | pfam domains | PF14818 | 3 | 1 | 17054 | 271 |
KIAA0408 |
| 4.692e-02 | -3.06 | IQ_SEC7_PH | pfam domains | PF16453 | 3 | 1 | 17054 | 271 |
IQSEC2 |
| 4.692e-02 | -3.06 | PKI | pfam domains | PF02827 | 3 | 1 | 17054 | 271 |
PKIA |
| 4.692e-02 | -3.06 | P4Ha_N | pfam domains | PF08336 | 3 | 1 | 17054 | 271 |
P4HA1 |
| 4.692e-02 | -3.06 | Popeye | pfam domains | PF04831 | 3 | 1 | 17054 | 271 |
BVES |
| 4.692e-02 | -3.06 | Cu2_monooxygen | pfam domains | PF01082 | 3 | 1 | 17054 | 271 |
MOXD1 |
| 4.692e-02 | -3.06 | Dapper | pfam domains | PF15268 | 3 | 1 | 17054 | 271 |
DACT1 |
| 4.692e-02 | -3.06 | RunxI | pfam domains | PF08504 | 3 | 1 | 17054 | 271 |
RUNX2 |
| 4.692e-02 | -3.06 | RGS-like | pfam domains | PF09128 | 3 | 1 | 17054 | 271 |
ARHGEF11 |
| 4.692e-02 | -3.06 | Myc_N | pfam domains | PF01056 | 3 | 1 | 17054 | 271 |
MYC |
| 4.696e-02 | -3.06 | ADAM32 (ADAM metallopeptidase domain 32) | protein interactions | 203102 | 21 | 2 | 17029 | 283 |
GAS6,PLXNA2 |
| 4.696e-02 | -3.06 | KCTD1 (potassium channel tetramerization domain containing 1) | protein interactions | 284252 | 21 | 2 | 17029 | 283 |
KCTD15,KCTD1 |
| 4.696e-02 | -3.06 | RASGRF1 (Ras protein specific guanine nucleotide releasing factor 1) | protein interactions | 5923 | 21 | 2 | 17029 | 283 |
CEBPA,MYC |
| 4.696e-02 | -3.06 | MYLK (myosin light chain kinase) | protein interactions | 4638 | 21 | 2 | 17029 | 283 |
PRKCA,MYC |
| 4.696e-02 | -3.06 | TRIM3 (tripartite motif containing 3) | protein interactions | 10612 | 21 | 2 | 17029 | 283 |
TRIM3,KIF21B |
| 4.696e-02 | -3.06 | TEAD3 (TEA domain transcription factor 3) | protein interactions | 7005 | 21 | 2 | 17029 | 283 |
VGLL4,WWTR1 |
| 4.698e-02 | -3.06 | regulatory region nucleic acid binding | molecular function | GO:0001067 | 878 | 21 | 17224 | 278 |
RUNX2,MSX1,MXI1,ZNF516,ZNF395,ZHX3,SOX21,MAFB,WNT11,CEBPA,SATB2,PRDM1,ZNF219,SATB1,TCF7L1,MYC,DLX2,DBP,SMYD3,BARX1,DDIT3 |
| 4.702e-02 | -3.06 | urogenital system development | biological process | GO:0001655 | 300 | 9 | 17256 | 270 |
EPCAM,LGR4,KLHL3,MYC,WFS1,WWTR1,ACTA2,WNT11,ACVR2B |
| 4.703e-02 | -3.06 | V$OCT_C | MSigDB lists | V$OCT_C | 245 | 8 | 17377 | 282 |
PRICKLE2,TCF7L1,TMOD2,PRDM1,PDE4D,MAP2K6,PLXNA2,MTUS1 |
| 4.703e-02 | -3.06 | MIYAGAWA_TARGETS_OF_EWSR1_ETS_FUSIONS_UP | MSigDB lists | MIYAGAWA_TARGETS_OF_EWSR1_ETS_FUSIONS_UP | 245 | 8 | 17377 | 282 |
IL17D,MAFB,MAPK13,RALGPS2,KMO,ABHD6,HMCN1,SPATA13 |
| 4.703e-02 | -3.06 | V$STAT4_01 | MSigDB lists | V$STAT4_01 | 245 | 8 | 17377 | 282 |
BDNF,RUNX2,CCDC148,SGK1,PDE4D,FANK1,SATB1,MTUS1 |
| 4.704e-02 | -3.06 | developmental growth | biological process | GO:0048589 | 347 | 10 | 17256 | 270 |
EPB41L5,BDNF,WWTR1,NLGN4X,WNT11,ACVR2B,PDE4D,PLEKHA1,APBA2,COBL |
| 4.706e-02 | -3.06 | positive regulation of nucleic acid-templated transcription | biological process | GO:1903508 | 1451 | 31 | 17256 | 270 |
SLC40A1,RUNX2,MSX1,ZNF516,ACVR1,LGR4,ARHGEF11,SOX21,MAFB,WWC1,SATB2,CEBPA,WNT11,OVOL2,ZNF219,RERE,DYRK1B,KDM7A,EPCAM,MYC,WWTR1,GTF2F2,EBF4,DAB2IP,DLX2,DBP,FANK1,BARX1,SMYD3,DDIT3,PARP9 |
| 4.706e-02 | -3.06 | positive regulation of transcription, DNA-templated | biological process | GO:0045893 | 1451 | 31 | 17256 | 270 |
SLC40A1,RUNX2,MSX1,ZNF516,ACVR1,LGR4,ARHGEF11,SOX21,MAFB,WWC1,SATB2,CEBPA,WNT11,OVOL2,ZNF219,RERE,DYRK1B,KDM7A,EPCAM,MYC,WWTR1,GTF2F2,EBF4,DAB2IP,DLX2,DBP,FANK1,BARX1,SMYD3,DDIT3,PARP9 |
| 4.717e-02 | -3.05 | Abhydrolase_1 | pfam domains | PF00561 | 22 | 2 | 17054 | 271 |
ABHD4,ABHD6 |
| 4.726e-02 | -3.05 | Dapper | interpro domains | IPR024843 | 3 | 1 | 18492 | 296 |
DACT1 |
| 4.726e-02 | -3.05 | RSN1_7TM | interpro domains | IPR003864 | 3 | 1 | 18492 | 296 |
TMEM63C |
| 4.726e-02 | -3.05 | RGS-like_dom | interpro domains | IPR015212 | 3 | 1 | 18492 | 296 |
ARHGEF11 |
| 4.726e-02 | -3.05 | PHM/PNGase_F_dom_sf | interpro domains | IPR008977 | 3 | 1 | 18492 | 296 |
MOXD1 |
| 4.726e-02 | -3.05 | Cu2_monoox_C | interpro domains | IPR024548 | 3 | 1 | 18492 | 296 |
MOXD1 |
| 4.726e-02 | -3.05 | KEN_sf | interpro domains | IPR038357 | 3 | 1 | 18492 | 296 |
ERN1 |
| 4.726e-02 | -3.05 | FAM131 | interpro domains | IPR026782 | 3 | 1 | 18492 | 296 |
FAM131C |
| 4.726e-02 | -3.05 | Pur_nucleotidase | interpro domains | IPR016695 | 3 | 1 | 18492 | 296 |
NT5DC2 |
| 4.726e-02 | -3.05 | Tensin_like_SH2 | interpro domains | IPR035012 | 3 | 1 | 18492 | 296 |
TNS1 |
| 4.726e-02 | -3.05 | Hlx-hairpin-Hlx_DNA-bd_motif | interpro domains | IPR003583 | 3 | 1 | 18492 | 296 |
EEPD1 |
| 4.726e-02 | -3.05 | DUF4482 | interpro domains | IPR027882 | 3 | 1 | 18492 | 296 |
KIAA0408 |
| 4.726e-02 | -3.05 | Distal-less_N | interpro domains | IPR022135 | 3 | 1 | 18492 | 296 |
DLX2 |
| 4.726e-02 | -3.05 | ZC2HC1 | interpro domains | IPR026319 | 3 | 1 | 18492 | 296 |
ZNF474 |
| 4.726e-02 | -3.05 | Ovo-like | interpro domains | IPR027756 | 3 | 1 | 18492 | 296 |
OVOL2 |
| 4.726e-02 | -3.05 | TDU_repeat | interpro domains | IPR006627 | 3 | 1 | 18492 | 296 |
VGLL4 |
| 4.726e-02 | -3.05 | 2oxoglutarate_DH_E1 | interpro domains | IPR011603 | 3 | 1 | 18492 | 296 |
OGDHL |
| 4.726e-02 | -3.05 | GFP | interpro domains | IPR009017 | 3 | 1 | 18492 | 296 |
HMCN1 |
| 4.726e-02 | -3.05 | Tscrpt_reg_Myc | interpro domains | IPR002418 | 3 | 1 | 18492 | 296 |
MYC |
| 4.726e-02 | -3.05 | Tscrpt_reg_Myc_N | interpro domains | IPR012682 | 3 | 1 | 18492 | 296 |
MYC |
| 4.726e-02 | -3.05 | Protein_kinase_C_a/b/g | interpro domains | IPR014375 | 3 | 1 | 18492 | 296 |
PRKCA |
| 4.726e-02 | -3.05 | Pro_4_hyd_alph_N | interpro domains | IPR013547 | 3 | 1 | 18492 | 296 |
P4HA1 |
| 4.726e-02 | -3.05 | Cu2_ascorb_mOase_N_sf | interpro domains | IPR036939 | 3 | 1 | 18492 | 296 |
MOXD1 |
| 4.726e-02 | -3.05 | TSHR/LHCGR/FSHR | interpro domains | IPR034298 | 3 | 1 | 18492 | 296 |
TSHR |
| 4.726e-02 | -3.05 | ERV/ALR_sulphydryl_oxidase | interpro domains | IPR017905 | 3 | 1 | 18492 | 296 |
QSOX1 |
| 4.726e-02 | -3.05 | ERV/ALR_sulphydryl_oxid_sf | interpro domains | IPR036774 | 3 | 1 | 18492 | 296 |
QSOX1 |
| 4.726e-02 | -3.05 | ABM_dom | interpro domains | IPR007138 | 3 | 1 | 18492 | 296 |
NECAB2 |
| 4.726e-02 | -3.05 | Cu2_ascorb_mOase-like_C | interpro domains | IPR014784 | 3 | 1 | 18492 | 296 |
MOXD1 |
| 4.726e-02 | -3.05 | PA14_dom | interpro domains | IPR011658 | 3 | 1 | 18492 | 296 |
B4GALNT3 |
| 4.726e-02 | -3.05 | AML1_Runt | interpro domains | IPR000040 | 3 | 1 | 18492 | 296 |
RUNX2 |
| 4.726e-02 | -3.05 | KEN_dom | interpro domains | IPR010513 | 3 | 1 | 18492 | 296 |
ERN1 |
| 4.726e-02 | -3.05 | Homez_homeobox_dom | interpro domains | IPR024578 | 3 | 1 | 18492 | 296 |
ZHX3 |
| 4.726e-02 | -3.05 | cAMP_dep_PKI | interpro domains | IPR004171 | 3 | 1 | 18492 | 296 |
PKIA |
| 4.726e-02 | -3.05 | Runt_dom | interpro domains | IPR013524 | 3 | 1 | 18492 | 296 |
RUNX2 |
| 4.726e-02 | -3.05 | ADF/Cofilin | interpro domains | IPR017904 | 3 | 1 | 18492 | 296 |
DSTN |
| 4.726e-02 | -3.05 | TF_Runt-rel_RUNX | interpro domains | IPR016554 | 3 | 1 | 18492 | 296 |
RUNX2 |
| 4.726e-02 | -3.05 | Tgfb1i1/Leupaxin/TGFB1I1 | interpro domains | IPR017305 | 3 | 1 | 18492 | 296 |
PXN |
| 4.726e-02 | -3.05 | Profilin1/2/3_vertebrate | interpro domains | IPR005454 | 3 | 1 | 18492 | 296 |
PFN2 |
| 4.726e-02 | -3.05 | Cu2_ascorb_mOase_N | interpro domains | IPR000323 | 3 | 1 | 18492 | 296 |
MOXD1 |
| 4.726e-02 | -3.05 | KGD_C | interpro domains | IPR031717 | 3 | 1 | 18492 | 296 |
OGDHL |
| 4.726e-02 | -3.05 | Popeye_prot | interpro domains | IPR006916 | 3 | 1 | 18492 | 296 |
BVES |
| 4.726e-02 | -3.05 | PHM7_cyt | interpro domains | IPR027815 | 3 | 1 | 18492 | 296 |
TMEM63C |
| 4.726e-02 | -3.05 | B9_dom | interpro domains | IPR010796 | 3 | 1 | 18492 | 296 |
B9D1 |
| 4.726e-02 | -3.05 | GPR137 | interpro domains | IPR029723 | 3 | 1 | 18492 | 296 |
GPR137C |
| 4.726e-02 | -3.05 | PHLDB1/2/3_PH | interpro domains | IPR037810 | 3 | 1 | 18492 | 296 |
PHLDB2 |
| 4.726e-02 | -3.05 | PET_prickle | interpro domains | IPR033723 | 3 | 1 | 18492 | 296 |
PRICKLE2 |
| 4.726e-02 | -3.05 | Aldolase_I_AS | interpro domains | IPR029768 | 3 | 1 | 18492 | 296 |
ALDOA |
| 4.726e-02 | -3.05 | C2_WWC | interpro domains | IPR037771 | 3 | 1 | 18492 | 296 |
WWC1 |
| 4.726e-02 | -3.05 | POLO_box_2 | interpro domains | IPR033695 | 3 | 1 | 18492 | 296 |
PLK2 |
| 4.726e-02 | -3.05 | FBA_I | interpro domains | IPR000741 | 3 | 1 | 18492 | 296 |
ALDOA |
| 4.726e-02 | -3.05 | Csc1_N | interpro domains | IPR032880 | 3 | 1 | 18492 | 296 |
TMEM63C |
| 4.726e-02 | -3.05 | LIM3_prickle | interpro domains | IPR033727 | 3 | 1 | 18492 | 296 |
PRICKLE2 |
| 4.726e-02 | -3.05 | G2_nidogen/fibulin_G2F | interpro domains | IPR006605 | 3 | 1 | 18492 | 296 |
HMCN1 |
| 4.726e-02 | -3.05 | LIM2_prickle | interpro domains | IPR033726 | 3 | 1 | 18492 | 296 |
PRICKLE2 |
| 4.726e-02 | -3.05 | RunxI_C_dom | interpro domains | IPR013711 | 3 | 1 | 18492 | 296 |
RUNX2 |
| 4.726e-02 | -3.05 | GlyclTrfase_18 | interpro domains | IPR026116 | 3 | 1 | 18492 | 296 |
CCDC126 |
| 4.726e-02 | -3.05 | InsP3_rcpt | interpro domains | IPR000493 | 3 | 1 | 18492 | 296 |
ITPR2 |
| 4.726e-02 | -3.05 | CFA20/WDR90/C3orf67 | interpro domains | IPR007714 | 3 | 1 | 18492 | 296 |
C3orf67 |
| 4.726e-02 | -3.05 | IQSEC_PH | interpro domains | IPR033742 | 3 | 1 | 18492 | 296 |
IQSEC2 |
| 4.726e-02 | -3.05 | srGAP1/2/3_SH3 | interpro domains | IPR035648 | 3 | 1 | 18492 | 296 |
SRGAP1 |
| 4.726e-02 | -3.05 | Reg_factor_effector_dom_sf | interpro domains | IPR011256 | 3 | 1 | 18492 | 296 |
HEBP1 |
| 4.726e-02 | -3.05 | Heavy-metal-associated_CS | interpro domains | IPR017969 | 3 | 1 | 18492 | 296 |
ATOX1 |
| 4.726e-02 | -3.05 | ALG1-like | interpro domains | IPR026051 | 3 | 1 | 18492 | 296 |
ALG1L |
| 4.726e-02 | -3.05 | Rab29/Rab38/Rab32 | interpro domains | IPR030697 | 3 | 1 | 18492 | 296 |
RAB38 |
| 4.726e-02 | -3.05 | Peptidase_S28 | interpro domains | IPR008758 | 3 | 1 | 18492 | 296 |
PRSS16 |
| 4.729e-02 | -3.05 | neuron projection development | biological process | GO:0031175 | 645 | 16 | 17256 | 270 |
BDNF,PLXNA2,EFNA3,ADCY1,KIF5C,PRKCA,JAM3,RERE,NEO1,NUMBL,GNAO1,CLMN,SGK1,DAB2IP,STXBP1,COBL |
| 4.737e-02 | -3.05 | GO_REGULATION_OF_WOUND_HEALING | MSigDB lists | GO_REGULATION_OF_WOUND_HEALING | 121 | 5 | 17377 | 282 |
PHLDB2,ABAT,PRKCA,UBASH3B,PRKCD |
| 4.737e-02 | -3.05 | GO_MUSCLE_CELL_DEVELOPMENT | MSigDB lists | GO_MUSCLE_CELL_DEVELOPMENT | 121 | 5 | 17377 | 282 |
TMOD2,CACNB4,BVES,SMYD3,FHOD3 |
| 4.737e-02 | -3.05 | MORF_FLT1 | MSigDB lists | MORF_FLT1 | 121 | 5 | 17377 | 282 |
MSX1,ITPR2,PRSS16,PLEKHB1,GPLD1 |
| 4.737e-02 | -3.05 | GSE5589_WT_VS_IL6_KO_LPS_STIM_MACROPHAGE_180MIN_UP | MSigDB lists | GSE5589_WT_VS_IL6_KO_LPS_STIM_MACROPHAGE_180MIN_UP | 121 | 5 | 17377 | 282 |
ENAM,ACVR1,KLHL31,NIPSNAP3B,WFS1 |
| 4.740e-02 | -3.05 | GO_LYMPHOCYTE_HOMEOSTASIS | MSigDB lists | GO_LYMPHOCYTE_HOMEOSTASIS | 50 | 3 | 17377 | 282 |
SLC40A1,TNFRSF17,PMAIP1 |
| 4.740e-02 | -3.05 | CHAUHAN_RESPONSE_TO_METHOXYESTRADIOL_UP | MSigDB lists | CHAUHAN_RESPONSE_TO_METHOXYESTRADIOL_UP | 50 | 3 | 17377 | 282 |
WNT11,MYC,GPR161 |
| 4.740e-02 | -3.05 | NAGASHIMA_NRG1_SIGNALING_DN | MSigDB lists | NAGASHIMA_NRG1_SIGNALING_DN | 50 | 3 | 17377 | 282 |
MAFB,RALGPS2,GPLD1 |
| 4.742e-02 | -3.05 | positive regulation of RNA biosynthetic process | biological process | GO:1902680 | 1452 | 31 | 17256 | 270 |
SLC40A1,RUNX2,MSX1,ZNF516,ACVR1,LGR4,ARHGEF11,SOX21,MAFB,WWC1,SATB2,CEBPA,WNT11,OVOL2,ZNF219,RERE,DYRK1B,KDM7A,EPCAM,MYC,WWTR1,GTF2F2,EBF4,DAB2IP,DLX2,DBP,FANK1,BARX1,SMYD3,DDIT3,PARP9 |
| 4.742e-02 | -3.05 | Signal Transduction | REACTOME pathways | R-HSA-162582 | 2548 | 46 | 10287 | 148 |
ARHGAP26,RGS16,RASAL2,DUSP8,LGR4,ARHGEF11,DOCK1,HEBP1,CYP4V2,ATP6V1E2,RHPN2,ITPR2,PRKCA,ABHD6,PFN2,TIAM2,RGS17,DACT1,MYC,PRKCD,GTF2F2,SRGAP1,DAB2IP,PDE4D,TSHR,OR2W3,GPR161,IL17RD,PXN,PDK1,PTPN6,ADCY1,STRADB,WWC1,WNT11,ACVR2B,SAV1,OR11H4,GRK3,TRIB3,TCF7L1,GNAO1,RASGRF2,WWTR1,ARHGAP28,MAPK13 |
| 4.756e-02 | -3.05 | negative regulation of Wnt signaling pathway | biological process | GO:0030178 | 210 | 7 | 17256 | 270 |
DAB2IP,WNT11,SHISA2,DACT1,BARX1,DDIT3,WWTR1 |
| 4.757e-02 | -3.05 | homeostatic process | biological process | GO:0042592 | 1564 | 33 | 17256 | 270 |
SLC40A1,SCN5A,QSOX1,LGR4,KLHL3,SLC9C1,SLC39A8,FBXO4,SFXN4,ATOX1,ADCY1,ATP6V1E2,SLC25A28,SLX1B,CEBPA,ABCC2,ITPR2,GAS6,RAB38,ABHD4,JAM3,NEO1,SLC30A4,PMAIP1,MYC,WFS1,ERN1,ALDOA,HK2,INAVA,BNIP3,TNFRSF17,DDIT3 |
| 4.759e-02 | -3.05 | FERM_1 | prosite domains | PS00660 | 21 | 2 | 12060 | 202 |
EPB41L5,PTPN21 |
| 4.761e-02 | -3.04 | Response to elevated platelet cytosolic Ca2+ | REACTOME pathways | R-HSA-76005 | 137 | 5 | 10287 | 148 |
QSOX1,GAS6,RAB27B,PRKCA,ALDOA |
| 4.762e-02 | -3.04 | embryonic placenta development | biological process | GO:0001892 | 87 | 4 | 17256 | 270 |
CEBPA,OVOL2,PRDM1,ST14 |
| 4.765e-02 | -3.04 | inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity | molecular function | GO:0005220 | 3 | 1 | 17224 | 278 |
ITPR2 |
| 4.765e-02 | -3.04 | U7 snRNA binding | molecular function | GO:0071209 | 3 | 1 | 17224 | 278 |
LSM11 |
| 4.765e-02 | -3.04 | hedgehog receptor activity | molecular function | GO:0008158 | 3 | 1 | 17224 | 278 |
B9D1 |
| 4.765e-02 | -3.04 | Toll-like receptor 2 binding | molecular function | GO:0035663 | 3 | 1 | 17224 | 278 |
TLR6 |
| 4.765e-02 | -3.04 | calcium-independent protein kinase C activity | molecular function | GO:0004699 | 3 | 1 | 17224 | 278 |
PRKCD |
| 4.765e-02 | -3.04 | mu-type opioid receptor binding | molecular function | GO:0031852 | 3 | 1 | 17224 | 278 |
GNAO1 |
| 4.765e-02 | -3.04 | alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity | molecular function | GO:0030144 | 3 | 1 | 17224 | 278 |
CCDC126 |
| 4.765e-02 | -3.04 | AP-3 adaptor complex binding | molecular function | GO:0035651 | 3 | 1 | 17224 | 278 |
RAB38 |
| 4.765e-02 | -3.04 | flavin-linked sulfhydryl oxidase activity | molecular function | GO:0016971 | 3 | 1 | 17224 | 278 |
QSOX1 |
| 4.765e-02 | -3.04 | fructose-bisphosphate aldolase activity | molecular function | GO:0004332 | 3 | 1 | 17224 | 278 |
ALDOA |
| 4.765e-02 | -3.04 | dopamine beta-monooxygenase activity | molecular function | GO:0004500 | 3 | 1 | 17224 | 278 |
MOXD1 |
| 4.765e-02 | -3.04 | corticotropin-releasing hormone receptor 1 binding | molecular function | GO:0051430 | 3 | 1 | 17224 | 278 |
GNAO1 |
| 4.765e-02 | -3.04 | protein binding, bridging involved in substrate recognition for ubiquitination | molecular function | GO:1990756 | 3 | 1 | 17224 | 278 |
ARRDC4 |
| 4.765e-02 | -3.04 | protein histidine phosphatase activity | molecular function | GO:0101006 | 3 | 1 | 17224 | 278 |
LHPP |
| 4.765e-02 | -3.04 | neurotrophin TRKB receptor binding | molecular function | GO:0005169 | 3 | 1 | 17224 | 278 |
BDNF |
| 4.765e-02 | -3.04 | aromatic amino acid transmembrane transporter activity | molecular function | GO:0015173 | 3 | 1 | 17224 | 278 |
SLC36A4 |
| 4.765e-02 | -3.04 | type 5 metabotropic glutamate receptor binding | molecular function | GO:0031802 | 3 | 1 | 17224 | 278 |
NECAB2 |
| 4.771e-02 | -3.04 | vasculature development | biological process | GO:0001944 | 494 | 13 | 17256 | 270 |
B9D1,ACVR1,RECK,ACTA2,WNT11,DAB2IP,PRDM1,ACVR2B,OVOL2,PRKCA,JAM3,DDIT3,GPLD1 |
| 4.771e-02 | -3.04 | central_nervous_system-occipital_lobe-other-ganglioglioma-dysembryoplastic_neuroepithelial_tumour | COSMIC cancer mutations | central_nervous_system-occipital_lobe-other-ganglioglioma-dysembryoplastic_neuroepithelial_tumour | 3 | 1 | 17385 | 281 |
KIAA1549 |
| 4.771e-02 | -3.04 | cervical | COSMIC cancer mutations | cervical | 3 | 1 | 17385 | 281 |
KIAA1549 |
| 4.771e-02 | -3.04 | central_nervous_system-cerebral_hemisphere-glioma-astrocytoma_Grade_I | COSMIC cancer mutations | central_nervous_system-cerebral_hemisphere-glioma-astrocytoma_Grade_I | 3 | 1 | 17385 | 281 |
KIAA1549 |
| 4.771e-02 | -3.04 | central_nervous_system-cerebellum-glioma-astrocytoma | COSMIC cancer mutations | central_nervous_system-cerebellum-glioma-astrocytoma | 3 | 1 | 17385 | 281 |
ACVR1 |
| 4.771e-02 | -3.04 | central_nervous_system-glioma-oligodendroglioma_Grade_III | COSMIC cancer mutations | central_nervous_system-glioma-oligodendroglioma_Grade_III | 3 | 1 | 17385 | 281 |
KIAA1549 |
| 4.771e-02 | -3.04 | GSE23114_WT_VS_SLE2C1_MOUSE_PERITONEAL_CAVITY_B1A_BCELL_DN | MSigDB lists | GSE23114_WT_VS_SLE2C1_MOUSE_PERITONEAL_CAVITY_B1A_BCELL_DN | 161 | 6 | 17377 | 282 |
IQCK,TMEM132C,DBP,PMAIP1,TBC1D8,EFNA3 |
| 4.771e-02 | -3.04 | GO_MYELIN_SHEATH | MSigDB lists | GO_MYELIN_SHEATH | 161 | 6 | 17377 | 282 |
STXBP1,HSPA2,JAM3,MARVELD2,GNAO1,EHD3 |
| 4.771e-02 | -3.04 | GSE14415_FOXP3_KO_NATURAL_TREG_VS_TCONV_DN | MSigDB lists | GSE14415_FOXP3_KO_NATURAL_TREG_VS_TCONV_DN | 161 | 6 | 17377 | 282 |
PDK1,RALGPS2,RNF122,SATB1,PTPN6,MYC |
| 4.771e-02 | -3.04 | GSE27859_MACROPHAGE_VS_CD11C_INT_F480_INT_DC_UP | MSigDB lists | GSE27859_MACROPHAGE_VS_CD11C_INT_F480_INT_DC_UP | 161 | 6 | 17377 | 282 |
CPNE2,IQSEC2,TLN2,PALLD,MAP2K6,ATOX1 |
| 4.771e-02 | -3.04 | GO_REGULATION_OF_PROTEIN_POLYMERIZATION | MSigDB lists | GO_REGULATION_OF_PROTEIN_POLYMERIZATION | 161 | 6 | 17377 | 282 |
SGK1,ARL2,TMOD2,PFN2,PRKCD,FHOD3 |
| 4.771e-02 | -3.04 | GSE2706_R848_VS_R848_AND_LPS_8H_STIM_DC_UP | MSigDB lists | GSE2706_R848_VS_R848_AND_LPS_8H_STIM_DC_UP | 161 | 6 | 17377 | 282 |
SGK1,PRKCA,SMPDL3A,EPDR1,RERE,TBC1D8 |
| 4.776e-02 | -3.04 | glomerulus development | biological process | GO:0032835 | 52 | 3 | 17256 | 270 |
ACTA2,LGR4,WWTR1 |
| 4.779e-02 | -3.04 | GO_REGULATION_OF_LYASE_ACTIVITY | MSigDB lists | GO_REGULATION_OF_LYASE_ACTIVITY | 84 | 4 | 17377 | 282 |
PRKCA,TSHR,WFS1,ADCY1 |
| 4.779e-02 | -3.04 | GO_REGULATION_OF_COAGULATION | MSigDB lists | GO_REGULATION_OF_COAGULATION | 84 | 4 | 17377 | 282 |
ABAT,PRKCA,UBASH3B,PRKCD |
| 4.779e-02 | -3.04 | LAMTOR5 (late endosomal/lysosomal adaptor, MAPK and MTOR activator 5) | protein interactions | 10542 | 49 | 3 | 17029 | 283 |
GAPDH,PDK1,DSTN |
| 4.779e-02 | -3.04 | SMAD6 (SMAD family member 6) | protein interactions | 4091 | 49 | 3 | 17029 | 283 |
ACVR2B,ACVR1,RUNX2 |
| 4.783e-02 | -3.04 | axon development | biological process | GO:0061564 | 396 | 11 | 17256 | 270 |
NUMBL,BDNF,PLXNA2,EFNA3,ADCY1,KIF5C,PRKCA,STXBP1,COBL,JAM3,NEO1 |
| 4.783e-02 | -3.04 | brain | COSMIC cancer mutations | brain | 16658 | 275 | 17385 | 281 |
ARHGAP26,ACVR1,DUSP8,LGR4,RECK,LSM11,ALG1L,CEBPA,PRKCA,ABHD6,NCS1,EPDR1,PMAIP1,CFHR1,TMEM37,TSHR,TBC1D8,KLHL23,KLHL3,WISP3,EXOC6B,DSTN,BNIP3L,SLC25A28,ABCC2,TNS1,ACVR2B,SAV1,SPATA9,PLK2,RASGRF2,ALDOA,ARHGAP28,MAPK13,TMOD2,TANC2,SCN5A,TMEM63C,ZHX3,CYP2J2,SLC36A4,TNFRSF10C,DYNC1I1,HPCAL4,NIPSNAP3B,MTUS1,IL17D,RALGPS2,MYC,ZIC5,SRGAP1,MOXD1,STXBP1,GPR161,EPB41L5,BDNF,QSOX1,SHISA2,ARRDC4,OR11H4,ZNF558,ADAMTS3,ISM1,LRRIQ3,QPCTL,EMILIN2,CLMN,IQSEC2,SMYD3,ZNF516,RASAL2,ST14,FAM131C,CCDC110,PLXNA2,COLEC10,TIAM2,TMEM53,ZNF827,KMO,DACT1,DAB2IP,PJA1,PDE4D,RAB27B,DNAH5,ATP6AP1L,KIAA1549,C3orf67,DZANK1,GAPDH,PDK1,SOX21,CYB5R2,SFXN4,ADCY1,NLGN4X,SATB2,WNT11,RAB38,TBC1D16,IQCK,WFS1,WWTR1,PLEKHG1,P4HA1,TNFSF15,DBP,COBL,KCTD1,C2orf88,CCDC148,MXI1,TMEM132C,BACE1,BIK,CCNJL,KIF5C,ARL2,GAS6,ZNF219,NEO1,RGS17,GPR155,SMPDL3A,PARP9,TMC7,MN1,B9D1,SLC40A1,PXN,MPP1,GPR137C,GPLD1,TRIB3,FGR,GNAO1,MYOM2,TNFRSF17,DDIT3,B4GALT7,PHC1,CCDC126,ACSL1,HEBP1,PTPN21,NDRG2,NRN1,ABAT,ITPR2,SLC2A13,CACNB4,ABHD4,HMCN1,EPCAM,PPM1E,FKBP9,CPNE2,MARVELD2,DLX6,TMEM143,TLN2,FANK1,OR2W3,ZNF391,PGBD5,PNRC1,CAPN5,ATOX1,TTC22,PLEKHA1,SGK2,NT5DC2,PLEKHB1,DYRK1B,SPNS1,TCF7L1,ERN1,DLX2,APBA2,GPR63,LONRF1,RGS16,RUNX2,ZNF395,BVES,FBXO4,UBASH3B,CYP4V2,ATP6V1E2,RASL11B,SETBP1,CHADL,SATB1,PFN2,FHOD3,NUMBL,SLC30A4,GAN,EBF4,BNIP3,NCEH1,VGLL4,BARX1,IL17RD,SPATA13,EFNA3,MAFB,STRADB,WWC1,WDR25,PPFIA4,LHPP,PRDM1,B4GALNT3,KIAA0355,HK2,RNF122,DOCK1,RHPN2,FAM198B,KIF21B,RADIL,CBLN1,KCTD15,RPS6KL1,ZDHHC23,EEPD1,ZNF521,MAP7,MYH15,TMEM120B,HSPA2,FAM78B,PHLDB2,UROS,SLC39A8,PTPN6,JAM3,CENPV,IFT81,LMLN,ANKRD31,RBPMS2,DISP1,NECAB2,PRSS16,ARHGEF11,BLVRB,OVOL2,PRKCD,RASD2,EHD3,GTF2F2,ACTA2,PRICKLE2,TRIM3,SGK1,CCDC122,KIAA0408,MSX1,NUAK2,OGDHL,EXOG,PALLD,TLR6,CTIF,RERE,FMO4,MAP2K6,KIAA0513,ZNF474,THAP10,RNF157,PKIA |
| 4.790e-02 | -3.04 | MYLLYKANGAS_AMPLIFICATION_HOT_SPOT_14 | MSigDB lists | MYLLYKANGAS_AMPLIFICATION_HOT_SPOT_14 | 3 | 1 | 17377 | 282 |
MYC |
| 4.790e-02 | -3.04 | chr3p | MSigDB lists | chr3p | 3 | 1 | 17377 | 282 |
PRKCD |
| 4.790e-02 | -3.04 | GO_PROTON_TRANSPORTING_ATP_SYNTHASE_ACTIVITY_ROTATIONAL_MECHANISM | MSigDB lists | GO_PROTON_TRANSPORTING_ATP_SYNTHASE_ACTIVITY_ROTATIONAL_MECHANISM | 3 | 1 | 17377 | 282 |
ATP6AP1L |
| 4.796e-02 | -3.04 | V$GATA6_01 | MSigDB lists | V$GATA6_01 | 246 | 8 | 17377 | 282 |
PPM1E,RUNX2,GPR155,SRGAP1,PLXNA2,WNT11,ZNF219,PKIA |
| 4.800e-02 | -3.04 | Femoral neck bone geometry(PMID:22087292) | GWAS genes | Femoral neck bone geometry(PMID:22087292) | 2 | 1 | 2388 | 58 |
HK2 |
| 4.800e-02 | -3.04 | Uric acid levels(PMID:18759275) | GWAS genes | Uric acid levels(PMID:18759275) | 2 | 1 | 2388 | 58 |
ARHGAP26 |
| 4.800e-02 | -3.04 | Functional MRI(PMID:20215924) | GWAS genes | Functional MRI(PMID:20215924) | 2 | 1 | 2388 | 58 |
KIAA0355 |
| 4.800e-02 | -3.04 | Suicide attempts in bipolar disorder(PMID:21423239) | GWAS genes | Suicide attempts in bipolar disorder(PMID:21423239) | 2 | 1 | 2388 | 58 |
TMEM132C |
| 4.800e-02 | -3.04 | Abdominal aortic aneurysm(PMID:20622881) | GWAS genes | Abdominal aortic aneurysm(PMID:20622881) | 2 | 1 | 2388 | 58 |
DAB2IP |
| 4.800e-02 | -3.04 | Sleepiness(PMID:17903308) | GWAS genes | Sleepiness(PMID:17903308) | 2 | 1 | 2388 | 58 |
PDE4D |
| 4.800e-02 | -3.04 | Colorectal cancer(PMID:19011631) | GWAS genes | Colorectal cancer(PMID:19011631) | 2 | 1 | 2388 | 58 |
RHPN2 |
| 4.805e-02 | -3.04 | ion homeostasis | biological process | GO:0050801 | 750 | 18 | 17256 | 270 |
SLC40A1,SCN5A,KLHL3,SLC9C1,SLC39A8,SFXN4,ATOX1,ATP6V1E2,SLC25A28,ABCC2,ITPR2,RAB38,NEO1,SLC30A4,WFS1,MYC,BNIP3,DDIT3 |
| 4.807e-02 | -3.04 | PDZ | smart domains | SM00228 | 145 | 6 | 9493 | 172 |
RHPN2,ARHGEF11,APBA2,RADIL,MPP1,TIAM2 |
| 4.811e-02 | -3.03 | GO_REGULATION_OF_TRANSMEMBRANE_RECEPTOR_PROTEIN_SERINE_THREONINE_KINASE_SIGNALING_PATHWAY | MSigDB lists | GO_REGULATION_OF_TRANSMEMBRANE_RECEPTOR_PROTEIN_SERINE_THREONINE_KINASE_SIGNALING_PATHWAY | 203 | 7 | 17377 | 282 |
RASL11B,MSX1,ACVR2B,ACVR1,DACT1,WWTR1,NEO1 |
| 4.815e-02 | -3.03 | FERM/acyl-CoA-bd_prot_sf | interpro domains | IPR014352 | 51 | 3 | 18492 | 296 |
EPB41L5,TLN2,PTPN21 |
| 4.815e-02 | -3.03 | Band_41_domain | interpro domains | IPR019749 | 51 | 3 | 18492 | 296 |
EPB41L5,TLN2,PTPN21 |
| 4.815e-02 | -3.03 | WW_dom | interpro domains | IPR001202 | 51 | 3 | 18492 | 296 |
WWC1,SAV1,WWTR1 |
| 4.822e-02 | -3.03 | Class I PI3K signaling events | Pathway Interaction DB | pi3kcipathway | 41 | 3 | 2226 | 45 |
SGK1,FGR,PLEKHA1 |
| 4.831e-02 | -3.03 | stomach-carcinoma-adenocarcinoma | COSMIC cancer mutations | stomach-carcinoma-adenocarcinoma | 15615 | 261 | 17385 | 281 |
ARHGAP26,ACVR1,DUSP8,LGR4,RECK,LSM11,ALG1L,CEBPA,PRKCA,ABHD6,NCS1,EPDR1,CFHR1,TMEM37,TSHR,TBC1D8,KLHL23,KLHL3,WISP3,EXOC6B,DSTN,BNIP3L,SLC25A28,ABCC2,TNS1,ACVR2B,SAV1,SPATA9,PLK2,RASGRF2,ARHGAP28,MAPK13,TMOD2,TANC2,SCN5A,TMEM63C,ZHX3,CYP2J2,SLC36A4,TNFRSF10C,DYNC1I1,HPCAL4,NIPSNAP3B,MTUS1,IL17D,RALGPS2,MYC,ZIC5,SRGAP1,MOXD1,STXBP1,GPR161,EPB41L5,BDNF,QSOX1,SHISA2,ARRDC4,OR11H4,ZNF558,ADAMTS3,ISM1,LRRIQ3,QPCTL,EMILIN2,CLMN,IQSEC2,SMYD3,ZNF516,RASAL2,ST14,C4A,CCDC110,PLXNA2,COLEC10,TIAM2,TMEM53,ZNF827,KMO,DACT1,DAB2IP,PJA1,PDE4D,RAB27B,DNAH5,ATP6AP1L,C3orf67,DZANK1,GAPDH,PDK1,SOX21,CYB5R2,SFXN4,ADCY1,NLGN4X,SATB2,WNT11,RAB38,TBC1D16,IQCK,WFS1,WWTR1,PLEKHG1,P4HA1,TNFSF15,DBP,KLHL31,COBL,KCTD1,CCDC148,MXI1,BACE1,CCNJL,KIF5C,ZNF219,NEO1,RGS17,GPR155,SMPDL3A,PARP9,TMC7,MN1,SLC40A1,PXN,MPP1,GPR137C,GPLD1,TRIB3,FGR,GNAO1,MYOM2,TNFRSF17,DDIT3,B4GALT7,PHC1,CCDC126,ACSL1,PTPN21,NDRG2,NRN1,ABAT,ITPR2,SLC2A13,CACNB4,ABHD4,HMCN1,EPCAM,PPM1E,FKBP9,CPNE2,MARVELD2,DLX6,TMEM143,TLN2,FANK1,OR2W3,ZNF391,PGBD5,PNRC1,CAPN5,TTC22,PLEKHA1,SGK2,PLEKHB1,NT5DC2,DYRK1B,SPNS1,TCF7L1,ERN1,DLX2,APBA2,GPR63,LONRF1,RGS16,RUNX2,ZNF395,BVES,FBXO4,UBASH3B,CYP4V2,ATP6V1E2,RASL11B,SETBP1,SATB1,PFN2,FHOD3,NUMBL,SLC30A4,GAN,BNIP3,NCEH1,VGLL4,BARX1,IL17RD,SPATA13,MAFB,STRADB,WWC1,WDR25,PPFIA4,LHPP,PRDM1,B4GALNT3,KIAA0355,HK2,RNF122,DOCK1,RHPN2,FAM198B,KIF21B,RADIL,CBLN1,KCTD15,RPS6KL1,EEPD1,ZDHHC23,ZNF521,MAP7,MYH15,TMEM120B,HSPA2,FAM78B,PHLDB2,UROS,PTPN6,SLC39A8,JAM3,CENPV,IFT81,LMLN,RBPMS2,DISP1,NECAB2,PRSS16,ARHGEF11,BLVRB,OVOL2,RASD2,EHD3,PRKCD,GTF2F2,SGK1,PRICKLE2,TRIM3,CCDC122,ACTA2,KIAA0408,MSX1,NUAK2,OGDHL,EXOG,PALLD,TLR6,CTIF,RERE,FMO4,MAP2K6,KIAA0513,ZNF474,THAP10,RNF157,PKIA |
| 4.839e-02 | -3.03 | regulation of cell motility | biological process | GO:2000145 | 909 | 21 | 17256 | 270 |
EPB41L5,PHLDB2,ACVR1,DOCK1,RECK,MPP1,SPATA13,PLXNA2,WNT11,GAS6,PRKCA,PFN2,ABHD6,JAM3,MTUS1,GPLD1,FGR,PLK2,SRGAP1,SGK1,DAB2IP |
| 4.850e-02 | -3.03 | hexose transmembrane transporter activity | molecular function | GO:0015149 | 22 | 2 | 17224 | 278 |
MFSD4A,SLC2A13 |
| 4.850e-02 | -3.03 | zinc ion transmembrane transporter activity | molecular function | GO:0005385 | 22 | 2 | 17224 | 278 |
SLC30A4,SLC39A8 |
| 4.852e-02 | -3.03 | LIU_SOX4_TARGETS_DN | MSigDB lists | LIU_SOX4_TARGETS_DN | 291 | 9 | 17377 | 282 |
KCTD15,PDK1,UROS,SCAMP1,DOCK1,KIF5C,BNIP3,OVOL2,SMYD3 |
| 4.853e-02 | -3.03 | human chr3p14.3 | chromosome location | human chr3p14.3 | 28 | 2 | 26185 | 331 |
IL17RD,ABHD6 |
| 4.853e-02 | -3.03 | human chr22q12.1 | chromosome location | human chr22q12.1 | 28 | 2 | 26185 | 331 |
MN1,GRK3 |
| 4.854e-02 | -3.03 | positive regulation of catabolic process | biological process | GO:0009896 | 397 | 11 | 17256 | 270 |
LONRF1,TRIB3,DACT1,PLK2,PRKCD,BNIP3L,HK2,BNIP3,CEBPA,DAB2IP,GPLD1 |
| 4.854e-02 | -3.03 | MAPT (microtubule associated protein tau) | protein interactions | 4137 | 119 | 5 | 17029 | 283 |
SGK1,MAPK13,STXBP1,UBASH3B,PRKCD |
| 4.861e-02 | -3.02 | WW_DOMAIN_2 | prosite domains | PS50020 | 49 | 3 | 12060 | 202 |
WWC1,SAV1,WWTR1 |
| 4.874e-02 | -3.02 | negative regulation of cell adhesion | biological process | GO:0007162 | 256 | 8 | 17256 | 270 |
EPB41L5,EPCAM,PHLDB2,ABAT,PTPN6,UBASH3B,PRKCD,PLXNA2 |
| 4.877e-02 | -3.02 | GSE13762_CTRL_VS_125_VITAMIND_DAY5_DC_DN | MSigDB lists | GSE13762_CTRL_VS_125_VITAMIND_DAY5_DC_DN | 122 | 5 | 17377 | 282 |
TMEM53,KLHL31,KLHL23,FBXO4,PTPN6 |
| 4.877e-02 | -3.02 | GO_OSTEOBLAST_DIFFERENTIATION | MSigDB lists | GO_OSTEOBLAST_DIFFERENTIATION | 122 | 5 | 17377 | 282 |
SATB2,WNT11,RUNX2,LGR4,WWTR1 |
| 4.877e-02 | -3.02 | GSE9946_IMMATURE_VS_MATURE_STIMULATORY_DC_DN | MSigDB lists | GSE9946_IMMATURE_VS_MATURE_STIMULATORY_DC_DN | 122 | 5 | 17377 | 282 |
KLHL23,HEBP1,FBXO4,WWTR1,GPR161 |
| 4.891e-02 | -3.02 | GSE17974_IL4_AND_ANTI_IL12_VS_UNTREATED_24H_ACT_CD4_TCELL_DN | MSigDB lists | GSE17974_IL4_AND_ANTI_IL12_VS_UNTREATED_24H_ACT_CD4_TCELL_DN | 162 | 6 | 17377 | 282 |
DZANK1,HERC6,SGK2,PALLD,GPR155,WWTR1 |
| 4.898e-02 | -3.02 | GO_REGULATION_OF_B_CELL_DIFFERENTIATION | MSigDB lists | GO_REGULATION_OF_B_CELL_DIFFERENTIATION | 22 | 2 | 17377 | 282 |
PRDM1,PTPN6 |
| 4.898e-02 | -3.02 | REACTOME_METAL_ION_SLC_TRANSPORTERS | MSigDB lists | REACTOME_METAL_ION_SLC_TRANSPORTERS | 22 | 2 | 17377 | 282 |
SLC40A1,SLC39A8 |
| 4.898e-02 | -3.02 | YANG_BREAST_CANCER_ESR1_BULK_DN | MSigDB lists | YANG_BREAST_CANCER_ESR1_BULK_DN | 22 | 2 | 17377 | 282 |
RGS16,APBA2 |
| 4.898e-02 | -3.02 | BIOCARTA_CHEMICAL_PATHWAY | MSigDB lists | BIOCARTA_CHEMICAL_PATHWAY | 22 | 2 | 17377 | 282 |
PXN,PRKCA |
| 4.898e-02 | -3.02 | GO_NEGATIVE_REGULATION_OF_EPITHELIAL_TO_MESENCHYMAL_TRANSITION | MSigDB lists | GO_NEGATIVE_REGULATION_OF_EPITHELIAL_TO_MESENCHYMAL_TRANSITION | 22 | 2 | 17377 | 282 |
DAB2IP,OVOL2 |
| 4.898e-02 | -3.02 | GO_MYOSIN_FILAMENT | MSigDB lists | GO_MYOSIN_FILAMENT | 22 | 2 | 17377 | 282 |
MYOM2,MYH15 |
| 4.898e-02 | -3.02 | GO_ACTIVIN_RECEPTOR_SIGNALING_PATHWAY | MSigDB lists | GO_ACTIVIN_RECEPTOR_SIGNALING_PATHWAY | 22 | 2 | 17377 | 282 |
ACVR2B,ACVR1 |
| 4.898e-02 | -3.02 | TACGGGT,MIR-99A,MIR-100,MIR-99B | MSigDB lists | TACGGGT,MIR-99A,MIR-100,MIR-99B | 22 | 2 | 17377 | 282 |
EPDR1,ADCY1 |
| 4.898e-02 | -3.02 | GO_CAMP_BINDING | MSigDB lists | GO_CAMP_BINDING | 22 | 2 | 17377 | 282 |
PDE4D,BVES |
| 4.898e-02 | -3.02 | chr6q16 | MSigDB lists | chr6q16 | 22 | 2 | 17377 | 282 |
GPR63,PNRC1 |
| 4.901e-02 | -3.02 | L-tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde | BIOCYC pathways | META_PWY-5651 | 5 | 1 | 902 | 9 |
KMO |
| 4.901e-02 | -3.02 | pyridoxal 5'-phosphate salvage | BIOCYC pathways | HUMAN_PLPSAL-PWY | 5 | 1 | 902 | 9 |
KLHL23 |
| 4.901e-02 | -3.02 | tetrapyrrole biosynthesis II (from glycine) | BIOCYC pathways | META_PWY-5189 | 5 | 1 | 902 | 9 |
UROS |
| 4.901e-02 | -3.02 | tetrapyrrole biosynthesis | BIOCYC pathways | HUMAN_PWY-5189 | 5 | 1 | 902 | 9 |
UROS |
| 4.901e-02 | -3.02 | L-valine degradation I | BIOCYC pathways | META_VALDEG-PWY | 5 | 1 | 902 | 9 |
ABAT |
| 4.904e-02 | -3.02 | Ikbkb (inhibitor of kappaB kinase beta) | protein interactions | 16150 | 3 | 1 | 17029 | 283 |
ACVR1 |
| 4.904e-02 | -3.02 | DLX3 (distal-less homeobox 3) | protein interactions | 1747 | 3 | 1 | 17029 | 283 |
PRKCA |
| 4.904e-02 | -3.02 | CBLN3 (cerebellin 3 precursor) | protein interactions | 643866 | 3 | 1 | 17029 | 283 |
CBLN1 |
| 4.904e-02 | -3.02 | NTNG1 (netrin G1) | protein interactions | 22854 | 3 | 1 | 17029 | 283 |
GAS6 |
| 4.904e-02 | -3.02 | LRMP (lymphoid restricted membrane protein) | protein interactions | 4033 | 3 | 1 | 17029 | 283 |
GAN |
| 4.904e-02 | -3.02 | Rps26 (ribosomal protein S26) | protein interactions | 27139 | 3 | 1 | 17029 | 283 |
PRICKLE2 |
| 4.904e-02 | -3.02 | ZNF45 (zinc finger protein 45) | protein interactions | 7596 | 3 | 1 | 17029 | 283 |
CEBPA |
| 4.904e-02 | -3.02 | GYPC (glycophorin C (Gerbich blood group)) | protein interactions | 2995 | 3 | 1 | 17029 | 283 |
MPP1 |
| 4.904e-02 | -3.02 | SCN1A (sodium voltage-gated channel alpha subunit 1) | protein interactions | 6323 | 3 | 1 | 17029 | 283 |
GAN |
| 4.904e-02 | -3.02 | TREML1 (triggering receptor expressed on myeloid cells like 1) | protein interactions | 340205 | 3 | 1 | 17029 | 283 |
PTPN6 |
| 4.904e-02 | -3.02 | GSP1 (Ran GTPase GSP1) | protein interactions | 851000 | 3 | 1 | 17029 | 283 |
PKIA |
| 4.904e-02 | -3.02 | AIFM2 (apoptosis inducing factor, mitochondria associated 2) | protein interactions | 84883 | 3 | 1 | 17029 | 283 |
MYC |
| 4.904e-02 | -3.02 | Pdcd6 (programmed cell death 6) | protein interactions | 18570 | 3 | 1 | 17029 | 283 |
CPNE2 |
| 4.904e-02 | -3.02 | GDF2 (growth differentiation factor 2) | protein interactions | 2658 | 3 | 1 | 17029 | 283 |
ACVR2B |
| 4.904e-02 | -3.02 | DNAH6 (dynein axonemal heavy chain 6) | protein interactions | 1768 | 3 | 1 | 17029 | 283 |
GAN |
| 4.904e-02 | -3.02 | FBLL1 (fibrillarin like 1) | protein interactions | 345630 | 3 | 1 | 17029 | 283 |
LGR4 |
| 4.904e-02 | -3.02 | TTLL6 (tubulin tyrosine ligase like 6) | protein interactions | 284076 | 3 | 1 | 17029 | 283 |
TBC1D16 |
| 4.904e-02 | -3.02 | CD34 (CD34 molecule) | protein interactions | 947 | 3 | 1 | 17029 | 283 |
PRKCD |
| 4.904e-02 | -3.02 | Skil (SKI-like) | protein interactions | 20482 | 3 | 1 | 17029 | 283 |
CPNE2 |
| 4.904e-02 | -3.02 | HAMP (hepcidin antimicrobial peptide) | protein interactions | 57817 | 3 | 1 | 17029 | 283 |
SLC40A1 |
| 4.904e-02 | -3.02 | AVPR1B (arginine vasopressin receptor 1B) | protein interactions | 553 | 3 | 1 | 17029 | 283 |
PRKCA |
| 4.904e-02 | -3.02 | KNDC1 (kinase non-catalytic C-lobe domain containing 1) | protein interactions | 85442 | 3 | 1 | 17029 | 283 |
MYC |
| 4.904e-02 | -3.02 | Mycbp2 (MYC binding protein 2, E3 ubiquitin protein ligase) | protein interactions | 290447 | 3 | 1 | 17029 | 283 |
PRICKLE2 |
| 4.904e-02 | -3.02 | Plekhb1 (pleckstrin homology domain containing, family B (evectins) member 1) | protein interactions | 27276 | 3 | 1 | 17029 | 283 |
ACVR1 |
| 4.904e-02 | -3.02 | OTULINL (OTU deubiquitinase with linear linkage specificity like) | protein interactions | 54491 | 3 | 1 | 17029 | 283 |
TNFRSF17 |
| 4.904e-02 | -3.02 | ced-2 (Cell death abnormality protein 2;hypothetical protein) | protein interactions | 176968 | 3 | 1 | 17029 | 283 |
PXN |
| 4.904e-02 | -3.02 | XYLT1 (xylosyltransferase 1) | protein interactions | 64131 | 3 | 1 | 17029 | 283 |
MYC |
| 4.904e-02 | -3.02 | Mycbp2 (MYC binding protein 2) | protein interactions | 105689 | 3 | 1 | 17029 | 283 |
CPNE2 |
| 4.904e-02 | -3.02 | DRC1 (dynein regulatory complex subunit 1) | protein interactions | 92749 | 3 | 1 | 17029 | 283 |
ALDOA |
| 4.904e-02 | -3.02 | SIGLEC11 (sialic acid binding Ig like lectin 11) | protein interactions | 114132 | 3 | 1 | 17029 | 283 |
PTPN6 |
| 4.904e-02 | -3.02 | RTTN (rotatin) | protein interactions | 25914 | 3 | 1 | 17029 | 283 |
GAN |
| 4.904e-02 | -3.02 | RSPO3 (R-spondin 3) | protein interactions | 84870 | 3 | 1 | 17029 | 283 |
LGR4 |
| 4.904e-02 | -3.02 | Grm5 (glutamate metabotropic receptor 5) | protein interactions | 24418 | 3 | 1 | 17029 | 283 |
PRKCA |
| 4.904e-02 | -3.02 | Ube2o (ubiquitin-conjugating enzyme E2O) | protein interactions | 217342 | 3 | 1 | 17029 | 283 |
CPNE2 |
| 4.904e-02 | -3.02 | Gne (glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase) | protein interactions | 114711 | 3 | 1 | 17029 | 283 |
KIAA1549 |
| 4.904e-02 | -3.02 | Rap2a (RAS related protein 2a) | protein interactions | 76108 | 3 | 1 | 17029 | 283 |
ACVR1 |
| 4.904e-02 | -3.02 | LMTK3 (lemur tyrosine kinase 3) | protein interactions | 114783 | 3 | 1 | 17029 | 283 |
MYC |
| 4.904e-02 | -3.02 | Nras (neuroblastoma ras oncogene) | protein interactions | 18176 | 3 | 1 | 17029 | 283 |
ACVR1 |
| 4.904e-02 | -3.02 | AVPR1A (arginine vasopressin receptor 1A) | protein interactions | 552 | 3 | 1 | 17029 | 283 |
PRKCA |
| 4.904e-02 | -3.02 | MYPOP (Myb related transcription factor, partner of profilin) | protein interactions | 339344 | 3 | 1 | 17029 | 283 |
PFN2 |
| 4.904e-02 | -3.02 | AMDHD1 (amidohydrolase domain containing 1) | protein interactions | 144193 | 3 | 1 | 17029 | 283 |
KLHL23 |
| 4.904e-02 | -3.02 | Act5C (Actin 5C) | protein interactions | 31521 | 3 | 1 | 17029 | 283 |
RERE |
| 4.904e-02 | -3.02 | Reps2 (RALBP1 associated Eps domain containing protein 2) | protein interactions | 194590 | 3 | 1 | 17029 | 283 |
PXN |
| 4.904e-02 | -3.02 | Rab33b (RAB33B, member RAS oncogene family) | protein interactions | 19338 | 3 | 1 | 17029 | 283 |
ACVR1 |
| 4.904e-02 | -3.02 | RGPD4 (RANBP2-like and GRIP domain containing 4) | protein interactions | 285190 | 3 | 1 | 17029 | 283 |
LGR4 |
| 4.904e-02 | -3.02 | NAA80 (N(alpha)-acetyltransferase 80, NatH catalytic subunit) | protein interactions | 24142 | 3 | 1 | 17029 | 283 |
PFN2 |
| 4.904e-02 | -3.02 | Bcor (BCL6 interacting corepressor) | protein interactions | 71458 | 3 | 1 | 17029 | 283 |
CPNE2 |
| 4.904e-02 | -3.02 | Tubb5 (tubulin, beta 5 class I) | protein interactions | 29214 | 3 | 1 | 17029 | 283 |
PRICKLE2 |
| 4.904e-02 | -3.02 | Chn1 (chimerin 1) | protein interactions | 108699 | 3 | 1 | 17029 | 283 |
ACVR1 |
| 4.904e-02 | -3.02 | DEFA1B (defensin alpha 1B) | protein interactions | 728358 | 3 | 1 | 17029 | 283 |
FBXO4 |
| 4.904e-02 | -3.02 | ADCY2 (adenylate cyclase 2) | protein interactions | 108 | 3 | 1 | 17029 | 283 |
ADCY1 |
| 4.904e-02 | -3.02 | CD300LF (CD300 molecule like family member f) | protein interactions | 146722 | 3 | 1 | 17029 | 283 |
PTPN6 |
| 4.915e-02 | -3.01 | cell-substrate junction | cellular component | GO:0030055 | 405 | 11 | 18223 | 280 |
ARHGAP26,EPB41L5,PHLDB2,LMLN,PXN,EHD3,CAPN5,ARL2,TNS1,PALLD,TLN2 |
| 4.924e-02 | -3.01 | ATP binding | molecular function | GO:0005524 | 1466 | 32 | 17224 | 278 |
RUNX2,ACSL1,ACVR1,PDK1,ADCY1,NUAK2,KIF5C,STRADB,ABCC2,ACVR2B,SGK2,KIF21B,PRKCA,GRK3,DYRK1B,TRIB3,FGR,PLK2,RPS6KL1,MAP2K6,PRKCD,EHD3,ERN1,GTF2F2,HK2,ACTA2,SGK1,MYH15,MAPK13,EPHB6,DNAH5,HSPA2 |
| 4.930e-02 | -3.01 | tissue migration | biological process | GO:0090130 | 88 | 4 | 17256 | 270 |
ACTA2,EPB41L5,PXN,GPLD1 |
| 4.933e-02 | -3.01 | ion transport | biological process | GO:0006811 | 1291 | 28 | 17256 | 270 |
TMC7,SLC40A1,SCN5A,TMEM63C,ACSL1,KLHL3,SLC9C1,SLC39A8,CYB5R2,SFXN4,ATOX1,ATP6V1E2,PPFIA4,SLC36A4,SLC25A28,ABCC2,ITPR2,GAS6,SLC2A13,SGK2,CACNB4,NCS1,SLC30A4,SGK1,TMEM37,STXBP1,ATP6AP1L,DDIT3 |
| 4.940e-02 | -3.01 | GO_REGULATION_OF_HOMEOSTATIC_PROCESS | MSigDB lists | GO_REGULATION_OF_HOMEOSTATIC_PROCESS | 431 | 12 | 17377 | 282 |
SCN5A,SLC30A4,UBASH3B,PTPN6,MYC,MAFB,SLX1B,ITPR2,PDE4D,ABAT,DDIT3,GPLD1 |
| 4.942e-02 | -3.01 | HMA_1 | prosite domains | PS01047 | 3 | 1 | 12060 | 202 |
ATOX1 |
| 4.942e-02 | -3.01 | NIDOGEN_G2 | prosite domains | PS50993 | 3 | 1 | 12060 | 202 |
HMCN1 |
| 4.942e-02 | -3.01 | ALDOLASE_CLASS_I | prosite domains | PS00158 | 3 | 1 | 12060 | 202 |
ALDOA |
| 4.942e-02 | -3.01 | ERV_ALR | prosite domains | PS51324 | 3 | 1 | 12060 | 202 |
QSOX1 |
| 4.942e-02 | -3.01 | B9 | prosite domains | PS51381 | 3 | 1 | 12060 | 202 |
B9D1 |
| 4.942e-02 | -3.01 | ABM | prosite domains | PS51725 | 3 | 1 | 12060 | 202 |
NECAB2 |
| 4.942e-02 | -3.01 | KEN | prosite domains | PS51392 | 3 | 1 | 12060 | 202 |
ERN1 |
| 4.942e-02 | -3.01 | RUNT | prosite domains | PS51062 | 3 | 1 | 12060 | 202 |
RUNX2 |
| 4.943e-02 | -3.01 | embryonic limb morphogenesis | biological process | GO:0030326 | 127 | 5 | 17256 | 270 |
B9D1,MSX1,RUNX2,RECK,DLX6 |
| 4.943e-02 | -3.01 | embryonic appendage morphogenesis | biological process | GO:0035113 | 127 | 5 | 17256 | 270 |
B9D1,MSX1,RUNX2,RECK,DLX6 |
| 4.949e-02 | -3.01 | MORF_FOSL1 | MSigDB lists | MORF_FOSL1 | 384 | 11 | 17377 | 282 |
PPM1E,IQCK,MSX1,RUNX2,SCAMP1,DOCK1,PDE4D,PRKCA,TANC2,CBLN1,PLEKHB1 |
| 4.949e-02 | -3.01 | oligoastrocytoma_Grade_II | COSMIC cancer mutations | oligoastrocytoma_Grade_II | 123 | 5 | 17385 | 281 |
WDR25,SHISA2,PTPN6,KIAA1549,COBL |
| 4.949e-02 | -3.01 | TEAD2 (TEA domain transcription factor 2) | protein interactions | 8463 | 83 | 4 | 17029 | 283 |
TRIM3,SATB2,SATB1,WWTR1 |
| 4.949e-02 | -3.01 | CEBPB (CCAAT enhancer binding protein beta) | protein interactions | 1051 | 83 | 4 | 17029 | 283 |
CEBPA,RUNX2,MYC,DDIT3 |
| 4.953e-02 | -3.01 | TURASHVILI_BREAST_LOBULAR_CARCINOMA_VS_DUCTAL_NORMAL_DN | MSigDB lists | TURASHVILI_BREAST_LOBULAR_CARCINOMA_VS_DUCTAL_NORMAL_DN | 85 | 4 | 17377 | 282 |
ACTA2,ISM1,CYP2J2,CYB5R2 |
| 4.953e-02 | -3.01 | FERRANDO_T_ALL_WITH_MLL_ENL_FUSION_UP | MSigDB lists | FERRANDO_T_ALL_WITH_MLL_ENL_FUSION_UP | 85 | 4 | 17377 | 282 |
MYOM2,FGR,DSTN,PTPN6 |
| 4.969e-02 | -3.00 | regulation of apoptotic process | biological process | GO:0042981 | 1570 | 33 | 17256 | 270 |
ACVR1,ARHGEF11,BIK,GAS6,TNFRSF10C,PRKCA,TIAM2,PMAIP1,MYC,PRKCD,SGK1,DAB2IP,BNIP3,EPHB6,STXBP1,FANK1,BDNF,SLC40A1,GAPDH,MSX1,NUAK2,BNIP3L,STRADB,WNT11,SAV1,SGK2,GPLD1,MAP2K6,WFS1,RASGRF2,PLK2,TNFSF15,DDIT3 |
| 4.970e-02 | -3.00 | Metal ion SLC transporters | REACTOME pathways | R-HSA-425410 | 25 | 2 | 10287 | 148 |
SLC40A1,SLC39A8 |
| 4.974e-02 | -3.00 | regulation of receptor recycling | biological process | GO:0001919 | 23 | 2 | 17256 | 270 |
TBC1D16,BVES |
| 4.974e-02 | -3.00 | motor neuron axon guidance | biological process | GO:0008045 | 23 | 2 | 17256 | 270 |
KIF5C,PLXNA2 |
| 4.974e-02 | -3.00 | regulation of metanephros development | biological process | GO:0072215 | 23 | 2 | 17256 | 270 |
MYC,WWTR1 |
| 4.974e-02 | -3.00 | zinc ion transmembrane transport | biological process | GO:0071577 | 23 | 2 | 17256 | 270 |
SLC30A4,SLC39A8 |
| 4.974e-02 | -3.00 | response to lithium ion | biological process | GO:0010226 | 23 | 2 | 17256 | 270 |
CEBPA,ADCY1 |
| 4.977e-02 | -3.00 | mesothelioma | COSMIC cancer mutations | mesothelioma | 4538 | 86 | 17385 | 281 |
ARHGAP26,ACVR1,DUSP8,LGR4,DOCK1,PTPN21,ITPR2,COLEC10,PRKCA,KIF21B,FKBP9,PPM1E,PMAIP1,DACT1,RPS6KL1,ZNF521,PJA1,PDE4D,RAB27B,DNAH5,HSPA2,GAPDH,PDK1,PTPN6,BNIP3L,NLGN4X,WNT11,PLEKHA1,RAB38,ACVR2B,SGK2,SAV1,PLEKHB1,DYRK1B,PLK2,RASGRF2,ERN1,ALDOA,TNFSF15,MAPK13,DISP1,RGS16,MXI1,RUNX2,ARHGEF11,FBXO4,BIK,SETBP1,ARL2,TNFRSF10C,GAS6,SATB1,RGS17,NUMBL,RALGPS2,MYC,PRKCD,RASD2,SRGAP1,TRIM3,SGK1,BNIP3,PXN,MPP1,SPATA13,NUAK2,PPFIA4,MAFB,STRADB,PRDM1,PALLD,GPLD1,TRIB3,FGR,ADAMTS3,FMO4,GNAO1,MAP2K6,HK2,CLMN,TNFRSF17,IQSEC2,RNF157,RNF122,SMYD3,DDIT3 |
| 4.978e-02 | -3.00 | PRAMOONJAGO_SOX4_TARGETS_UP | MSigDB lists | PRAMOONJAGO_SOX4_TARGETS_UP | 51 | 3 | 17377 | 282 |
BNIP3,TRIB3,MXI1 |
| 4.978e-02 | -3.00 | NATSUME_RESPONSE_TO_INTERFERON_BETA_DN | MSigDB lists | NATSUME_RESPONSE_TO_INTERFERON_BETA_DN | 51 | 3 | 17377 | 282 |
GAS6,GAPDH,TSHR |
| 4.978e-02 | -3.00 | BERNARD_PPAPDC1B_TARGETS_DN | MSigDB lists | BERNARD_PPAPDC1B_TARGETS_DN | 51 | 3 | 17377 | 282 |
KIF5C,MXI1,SCAMP1 |
| 4.984e-02 | -3.00 | Homeobox | pfam domains | PF00046 | 209 | 7 | 17054 | 271 |
SATB2,MSX1,DLX2,SATB1,ZHX3,BARX1,DLX6 |
| 4.992e-02 | -3.00 | GABAergic synapse | KEGG pathways | hsa04727 | 88 | 4 | 7161 | 113 |
ABAT,PRKCA,GNAO1,ADCY1 |
| 4.992e-02 | -3.00 | GABAergic synapse | KEGG pathways | ko04727 | 88 | 4 | 7161 | 113 |
ABAT,PRKCA,GNAO1,ADCY1 |