| P-value | ln(P) | Term | GO Tree | GO ID | # of Genes in Term | # of Target Genes in Term | # of Total Genes | # of Target Genes | Common Genes |
|---|
| 2.741e-132 | -302.93 | intracellular part | cellular component | GO:0044424 | 14262 | 2545 | 18223 | 2701 |
HECA,ZBTB10,ABCC10,HEXB,TGOLN2,CCNL2,SYNRG,FBXO22,EEF2K,RAD23B,ATP13A3,DNM2,ZNRD1,FTSJ3,USP34,ERCC1,NRAS,EHMT1,KIF15,HNRNPF,WDHD1,MIER2,DIDO1,MCM2,RAB22A,MID1IP1,SMAD2,RPS27A,MYO18A,OGT,MPV17,COX5A,KLHL42,SMAD1,ZNF75A,ANXA11,SLC25A33,GGA1,SEC61G,CCZ1,MUM1,TRIO,RAB23,KCTD17,HAUS4,EIF2AK4,APH1B,PARN,CDC73,MYL6B,ATG4A,TMEM179B,PDXP,SMC3,TNPO3,GEMIN4,MVP,NUP85,PABPC1,NSUN4,PPP6R1,PPA1,IFRD1,AGGF1,RBM42,FOXK1,GTPBP4,MAP7D1,MRPL16,ELK1,EIF4H,RDH11,MAGED2,KPNA1,ETS2,TYW5,WIPI2,RUFY3,PDLIM5,ACSF2,FAM72D,EXOC3,RHOG,C5orf30,VTI1A,STARD7,INO80E,SLC35B2,RCOR3,LCLAT1,CPNE3,KIAA1147,RBM23,AHCTF1,ZNF420,TBC1D14,GMEB1,NSFL1C,SEPT11,ZNF226,GPD1L,ZC3H3,PDCL3,SNX8,ERMP1,EID1,IDH3A,NBPF11,POLR2D,HTATIP2,MEF2D,TMEM147,GSTCD,MAT2A,VPS26B,CORO1C,NSMCE2,CAMKMT,PPP5C,PITRM1,TUBB,COMMD10,ZNF445,SRSF6,CCM2,HABP4,FLOT1,ABHD14B,ATG2B,ATP5F1B,HDGFL2,NEXMIF,TUT4,PPP1R3B,GOLM1,ZBTB45,HUWE1,ZNF260,NAA50,ANXA5,LTN1,KANSL2,UBE3B,NAP1L4,ST8SIA2,ZNF710,RPL22L1,MED22,SPTAN1,STAU1,DDX24,TCTEX1D2,TACC1,USP42,MRS2,LDHA,HEBP2,LLPH,RAB3IP,PICALM,SH3BP5,ACOX1,PARG,FAM3C,AEN,PARP10,YWHAH,WDR45B,THAP5,FAM129A,TRIM11,YTHDC2,RBM8A,SNX15,ENSA,NENF,SND1,RUFY1,TRIM65,ZER1,PRNP,KRR1,RAB8A,NUP210,NOC2L,EIF5,TACC3,RYBP,PTPN18,MIOS,SNRPB,CDC6,PBRM1,UTP3,ODC1,USP21,TRAM2,FBXO28,GRIPAP1,ARRDC1,DVL1,NUMB,ZNF564,FUBP1,CTU2,PARP12,ZCCHC9,CENPF,LAMTOR3,CHCHD2,NCKAP1,RSAD1,TNS3,SUB1,RINL,MBD2,SSBP3,KIF13B,XPA,AHCY,RBM3,GLE1,MRPL48,LRSAM1,NSDHL,AMD1,CAMSAP1,ZNF761,METTL22,STYXL1,APPL1,BBS12,RXRB,SDHB,PCM1,GALNT2,TMEM168,NLRC5,RUVBL2,BTBD10,MYO9A,ECPAS,CCNB2,USP7,GLT8D1,RPLP2,SUCLG1,ARID2,TMX4,SLC2A1,ATP6V1B2,LYN,PCBP1,BCAP31,MRPL50,VAV1,PSMA6,ZNF473,KMT5C,BRPF3,ZNF302,TARDBP,BCAP29,SPIDR,CTDSP2,PRPF19,PPIF,KDM3B,MND1,CLCN3,BIRC3,RAB7A,PPIE,CHMP2B,VDAC1,TMEM201,EIF3H,GLOD4,IDE,DHX16,UHRF2,CHMP4B,XRCC3,PARD3,BCL2L12,NIFK,C19orf53,MCM10,MTERF1,KLHL21,PDAP1,TMX3,CDCA8,GTF3A,ARF1,CDK11B,PAGR1,TUBGCP2,DNAJB9,HOMER1,POLR1B,RNF5,RBM15B,PPAN,RHOA,RPRD1A,BTAF1,TOP3A,ARHGEF12,PCGF1,DDX23,RAB18,TRIM26,PDCD6,NEK1,ATP6V1D,FAM110A,L3MBTL3,NEIL3,CTBS,BBX,IMPDH1,TAF12,NR2F2,PGAM1,ARHGAP23,HIPK3,IFI16,TXN,NUP188,PNISR,H2AFZ,TMEM203,PRKCSH,USP39,UBE2I,PARK7,SLC25A37,GLMP,RAB4A,TRA2B,SUCLG2,TAF5L,CISD2,SMARCE1,ZNF800,CDC5L,ZNF524,SGCE,NSUN2,USP22,CLNS1A,EIF3A,ZMYM3,DOT1L,IWS1,MKNK1,WAS,KIF18B,TPP2,C1orf109,ZMAT3,FAM72C,B4GALT2,PRPF38B,RECQL,C9orf78,EWSR1,GADD45G,RRM1,DNAAF5,ACAP1,B4GALT1,CYCS,FAM136A,SUPT7L,ZNF518A,TMEM165,WDR48,SPAG5,CNOT3,NPLOC4,RTKN,TMEM250,CEP104,EXOSC7,KLHL5,LRRC8D,PPP4R1,MSH2,PIGG,FBXL7,OSTF1,MRPL40,TNRC18,SYTL3,APOL1,EIF5A,GCC2,PRIM2,ELL2,COQ8A,RDH10,USF3,MFNG,RPS24,GORASP2,CAPZA2,ADRB2,MTR,CCT8,PHF6,PFDN5,GOLGA2,EPOP,RBMX,MED15,PIAS2,APPL2,SAMD8,CDKN2A,NUDT3,ZNF511,NDC1,ATXN3,RAF1,C2orf49,CD320,EPM2A,CCNA2,MTMR4,BRI3,TAP2,AQR,TP53BP2,CDK12,ILKAP,SAP30,BRD4,DRAP1,NARF,LRRC8A,ELP4,ABHD11,PKMYT1,ASB13,SERP1,TRIM28,SUPT16H,EIF3K,CHMP4A,CERS6,ATF6,XRCC4,PRPF4B,NDUFS1,DEPDC1,MECP2,SECISBP2,SPDL1,HMG20A,WWP2,JAKMIP1,SLC25A36,CCNK,DNAJC8,ELP5,AXIN2,CARF,CITED2,KAT2A,ANKRD37,TMEM126B,RABIF,ADSL,PACS1,BMS1,KCNQ1,OTUD3,ARSK,MACF1,KLF6,COMMD4,KIF11,FADD,SH3GLB1,SMAP2,MYO1F,CBX3,SELENOW,INF2,TMEM127,PPP1R11,DUSP11,DDX5,WDR62,TAF6,ESPL1,PURA,DEF6,IPO4,FAM83G,DDB1,CCNC,PIGM,LYRM4,PTP4A3,UBE2Q1,BRIX1,MRPL19,ZNF696,SF3B2,PCYOX1L,CDC42,SYNM,GOT2,JAZF1,HADHB,RPF2,SLC35C2,CARM1,SRPK2,WDR41,LARS,LRBA,RIOX2,TMEM216,SUMF2,KMT2C,OGFR,MPC1,ASF1B,RPL37,MAN2A2,EIF4ENIF1,NIP7,U2SURP,MIA2,ZNF268,VPS4A,ATP6V0E1,PPP1R2,PM20D2,XPNPEP3,RGS2,LYAR,EI24,FAM89B,POLR2I,SUGP2,GBA,SYVN1,EIF2A,DAPK3,ARHGAP15,MASTL,UAP1,NFIL3,FN3KRP,YWHAZ,CTSA,TMEM14A,TOB1,TSEN15,ADNP2,TCF12,PRKAB1,MDH2,SMARCA4,ORC1,RRN3,UBXN2A,IARS,CD3EAP,KIF14,EXOSC1,CS,CLTB,DNAL4,CSTF1,CHP1,POU2AF1,UBQLN4,PPP1R18,NXT1,PGGT1B,SMU1,LSM8,ATXN1,GLO1,BICD2,OGDH,EDEM2,TOLLIP,FANCE,MBD3,RPS9,PDHX,ALKBH6,DUS3L,SURF4,ARNTL,ANP32E,FKBP5,CCDC125,PDCD2L,ABCA1,CWC25,GCLM,ZNF316,RAE1,DCTN2,NUP54,CHIC2,PAWR,MXD4,DCUN1D4,PIP4K2A,XPR1,FERMT3,KIF5B,KLHL20,SEC24C,RRBP1,DUS2,ARHGEF2,ANP32A,STAT3,MYO5A,AMPD2,TXNL1,COA3,PHF20L1,DCAF6,FAM49B,ATP2C1,RFFL,COG1,RCOR1,PRMT2,TFEB,LEMD2,CTSL,UPF1,ELMO1,ZC3H7B,DTX4,ZMIZ1,HRAS,TERF1,SLF2,CCDC93,TMED7,FGFR1OP,MAP3K7CL,PIGQ,AGPAT1,CNTROB,PPP1R16B,MIEN1,EDRF1,MIS12,CIPC,GSDMB,PDS5B,NUP153,SENP1,PGAP2,TMEM115,AATF,DCUN1D5,PLEKHF2,BRMS1,TRIM47,PWWP2B,WDR11,AXIN1,SMG9,LONP2,NDUFV2,PHF23,CERK,EZH1,ITGB5,LMNA,MCTS1,DDX56,EIF2S2,FOXN2,CARS2,RB1CC1,PRRC2A,ZMYND11,PGS1,MYBL2,SRSF5,MPG,MATR3,CYB5A,NCDN,POLR2J,SETD3,TEX30,PTAR1,CNOT6,NDE1,EGLN1,ZNF207,ANKRD27,ABCA3,SARNP,IVNS1ABP,RMI2,TMEM97,MON1B,NUF2,RXYLT1,NIT2,ZNF267,TCF19,KTN1,APP,CLUAP1,PRKD3,ATP2A2,UTP18,GRSF1,DUT,ZCCHC2,ANAPC7,FAM76B,RNF19A,CLN6,GCC1,TMEM9,RNF169,ATP6V1G1,ADCY7,ENPP4,RNPS1,CDCA2,FKBP3,DDX17,CHCHD3,PEX5,CDC16,HIPK2,NT5C3B,MBOAT1,TICAM1,PDXK,ZBTB11,TMBIM4,ANXA6,GMCL1,UBE4A,ETS1,WRB,PLPP5,PNO1,ZNF92,CAPN2,ADD3,SUV39H2,TPCN1,TMX1,HNRNPM,LYPLA2,MFSD12,LDHB,PPP3CA,POLK,JTB,MTMR12,PDE3B,CIP2A,KIF18A,CCDC6,WNT5B,MAPK6,C4orf46,SLC25A19,RGL1,PSAP,WDR76,IGBP1,FAF1,SNAPIN,COX15,AGRN,THOC1,GPBP1L1,GNPDA1,PPP1R15B,CSNK2A1,EBNA1BP2,BIRC2,GIT2,ATPAF1,ABL2,DLG5,XRCC2,ZFYVE27,MCMBP,PTPRK,CDC37,SP3,METTL1,EXOSC6,HARS,CYSTM1,ESYT1,ANLN,RAB5B,RHEB,DPYSL3,TBC1D17,CDCA4,TIMM13,TONSL,NRM,NAGLU,ACTB,ZNF45,SINHCAF,C2CD5,TMUB1,CTCF,ASAH1,DOCK11,ASXL2,CRLF3,LRRC14,NUS1,CMTR2,SLC27A4,MDFIC,AFF1,MAML1,CYTH1,NQO2,UTP15,EIF2AK1,EIF4G2,ZDHHC3,SPATA33,MOSPD3,CDC27,SNAP23,TBPL1,PRMT7,ATP5F1A,KCTD7,NDUFA5,CYLD,UGP2,DYNLL1,COPE,HCFC1R1,ZADH2,GGPS1,RPAIN,ABRACL,RAD23A,SEC11A,PDK2,ATP6V0B,ZBTB21,STRBP,TNFAIP8,DUS4L,MRPL34,PDCD2,SAP30L,RPL29,TIMP2,RPL35,BTG2,TUBGCP5,FRAT2,DNAJC9,MTMR6,NFATC2,KDM1B,USP36,MRPL2,ATP1A1,CLK3,MAFK,PSMD3,NDUFA11,CEP55,ZNF436,DNAJC17,NCOA1,SLC25A39,ZC3HC1,ZNF146,SMAP1,GOLIM4,CDC40,GNE,SMC6,ARFIP2,NKRF,CHAC2,BZW2,WRNIP1,SS18L1,CENPM,PTGES3,CAMK2G,MLEC,ZNF202,PPWD1,FAM50B,RHOT2,NEU1,GOLGA7,PGRMC1,GLG1,FAM126A,SPCS3,RPS6KC1,UBE2C,PPCS,NDUFB6,ZDHHC8,CCNB1,COMMD6,POLR3K,ABHD14A,RIC1,C14orf119,UTP25,SNUPN,ASAP2,TFG,PLCL2,SPTSSA,SEH1L,ATG9A,PBK,ARHGAP45,MKI67,DDX20,GALNT7,SLC17A5,AMDHD2,CCNF,FOXRED1,RBM47,WDR4,SARAF,DHTKD1,TRAF5,HDAC2,PWWP2A,HSPH1,MAPRE1,LIME1,CHTF18,ADO,KIF23,SLC35B1,PMF1,NOTCH2,COPG2,JMY,NDUFAF6,FKBP1A,SLC31A1,SNX18,ATIC,CTPS1,SLC25A51,ATP6V0A2,RNF135,PIKFYVE,LPCAT1,EEF1D,TMED2,PHF10,FTL,DDX28,ZNF84,SIGMAR1,PIP4K2C,PLEC,CYFIP2,KDM3A,SF3A2,FAS,EPRS,ZNF777,CSNK1G1,QARS,DCAF11,PPP3R1,TCOF1,NRBP1,CABLES1,DNMT3A,RWDD1,TRIP10,RPS6KA1,SF3B1,CAST,SUZ12,GPR89A,RAC1,OLA1,SNN,GNB2,SDE2,FLAD1,APLP2,KDM2A,CDKN1B,TNPO2,TALDO1,GPX4,ATP13A1,MAPRE2,RFC3,ERF,TAOK1,CUL3,SLBP,POLG2,PSMB9,H2AFV,GAR1,DHX57,CENPU,SOCS7,NSA2,HSPA4,JAK1,MRPL55,TBL3,FAAP100,GOLGA8A,H2AFX,SEL1L,B4GALT3,PDCD11,CSNK1D,ATMIN,POLQ,POU3F2,OTUD5,NCOR2,ANKRD13D,PKP4,SCAMP3,TWNK,BABAM1,CDCA3,SLC25A12,BLM,GTF2F1,RPL17,CRAT,AHSA1,PRC1,UPF2,SLC38A10,COPS7B,CNOT6L,CNPY3,IFT46,UBE2M,TSHZ1,ZFP64,STRIP1,DENND1B,DENND4C,WDR18,ILF3,RPL8,LRRC1,RHOT1,MARK2,TSR2,ECH1,PRDX1,POLR2A,FBXO21,NUCB1,GNA12,PLD3,C1orf131,PFDN4,PRDX3,HNRNPH3,CCZ1B,STX18,TFDP1,NAXE,KHSRP,ASNA1,CPEB2,BYSL,VPS29,S100PBP,DDX52,MIB2,ADA2,PTMS,IER2,NOP2,UBN1,NF1,DCAF15,ALKBH5,MOGS,UBE2Z,TAF6L,MAPK14,BECN1,SNAPC4,RNF103,BCAT2,MBD4,CYREN,CMSS1,METTL14,IMPAD1,RCSD1,PHTF1,SRI,KHDC4,KIF22,ZBTB22,NFU1,OGG1,TRIM14,ELOF1,COPS8,FYTTD1,TRIM8,RRM2,SOX4,ABHD5,PAF1,CXXC4,UBTF,SPATA2,ATXN2L,PQBP1,IARS2,GALNT10,ROCK1,STARD3NL,CEP170B,RPS15,PIGN,AGTRAP,CDIP1,CIB1,XPO7,SRRT,APOPT1,ZNF449,CAPZA1,KIFAP3,BCL2,GLTP,N4BP2,HP1BP3,VOPP1,ISG15,CAND1,GNAS,TSC1,RBM25,CDCA5,ZFP90,RBBP4,NANP,NIPSNAP2,HNRNPDL,ZBTB24,SMARCD1,WASF2,MBD1,MMACHC,TOMM20,FAM92A,IFI27L1,MPHOSPH8,GNPNAT1,HNRNPUL2,NSD3,CHD1,MEAF6,MIEF1,BABAM2,CCDC50,AKAP8,PARL,RPN2,CHTOP,F2R,ABI1,TMEM14C,SCYL3,HTRA2,RLIM,MOSPD1,FAM172A,ZNF500,PSMB7,NLN,WIPF1,BOLA1,ERBIN,NDUFB1,BUD13,PEF1,EIF3G,BTBD1,TAB2,TULP3,CHCHD1,WDR59,CANT1,SCARB1,GAS2,USP11,SMURF1,PPP2R2D,CDS2,MAGEH1,MRPL42,EYA1,CDK2AP2,MRPS26,LETMD1,KLF13,HDDC2,RGS1,MAN1A1,FBXO5,GART,PELO,TANK,BRD7,MRPL11,SAMD4B,ZDHHC18,GTF3C6,POLR3GL,WDR81,MEN1,ZNF407,MFN2,COX8A,ZRANB2,SRSF3,MBD6,ATP6V1C1,TATDN1,IDH3B,TSC2,LACTB2,CMTM6,RBM4,ZNF275,RPL23A,CDKN2C,NAPG,USF1,DNAAF2,MECR,AP1M1,UPRT,CRY2,ECD,MOB1A,RNF26,LRRC59,TIPARP,ANKRD9,RHBDD2,MGAT5,MRPL57,BAK1,RHOBTB3,ZNF559,GABPA,NUTF2,COA7,ARF4,GINS4,KRIT1,BOLA3,AHNAK,RAD18,PDRG1,RNASEL,CHPF2,OAZ1,SMNDC1,PDCD4,NXT2,HIVEP3,CLSPN,RHOC,DHX9,PDCD7,PSMD9,HAUS2,COPB2,CD59,TFAP4,RNFT1,MEGF8,RIMS3,RBM34,FBXO7,EFTUD2,MYDGF,CPSF4,MRPL21,PHKG2,LUC7L2,SRSF11,EIF3L,MAPKAPK3,MTA2,MTFR2,SF3B6,ERO1A,ITM2A,SSR2,USP10,BCLAF1,MTX1,SFXN5,FNTA,PDLIM1,TXNDC16,CFAP20,ZNF830,MRPL3,NUP58,ALS2,FAM72A,KARS,TRIM41,GGNBP2,NQO1,POC1A,ANK3,PTTG1,TPX2,TBC1D13,DAZAP2,GLRX3,STMN1,REPS1,SH3BP1,MTA1,UBA5,CLCN6,NABP1,INTS12,MICU2,RPRD1B,CGGBP1,CPNE1,ULK3,SEC61B,POLR2L,FAM118B,GOPC,KAT7,CIRBP,E2F3,RPL38,CRNKL1,PFKFB3,GORAB,RAB1A,KIF2A,PPP2CA,ALDH3B1,LSM6,CCDC14,RNF38,CENPBD1,SNRPG,DMWD,USP13,MZT1,ZFP91,TRMT6,IP6K2,WDR5,SLC25A43,IFT27,PMVK,NEIL2,SAPCD2,RRP36,SRXN1,RPA2,PSMD2,PDCD10,CLIC4,COQ4,ARF5,ARHGEF1,FBXL19,GTF2H2,UTP20,MAGT1,GPS2,DBI,SSNA1,AAMDC,WDR13,FANCI,PAPOLA,CREM,TET3,FANCL,GLIS2,TIMM23,INTS1,POP7,SLC44A1,MTPN,ASB6,PLK1,RPP25,SEPT9,CELSR2,RBX1,APH1A,RAD51AP1,ZBED5,PSMG1,CKAP2L,UBE2V1,EAF2,KRTCAP2,LUC7L,LSG1,NECAP2,ALG3,TRIM4,AGPAT2,CHD3,E2F4,ZNF367,KPNA2,PRPF4,DNAJC30,BEND6,CLN3,FAM208A,NGLY1,POT1,MYL12B,CCDC137,RMND5A,HJURP,NEMP2,PHB2,DNAJB2,NKD2,SDC2,KLC1,COX4I1,CDK13,DNAJB1,RAB6A,CNOT11,ARID1B,C1GALT1,MLX,UBE2Q2,CCP110,ZNF746,ARL6IP1,CTR9,ICE2,NIPSNAP1,ABHD2,DCAF8,ACSL3,LDB1,MAP4K3,ARMC8,NPIPA1,RBM38,RMC1,IRF5,NMT2,RPL36,HAUS8,PAXX,MBIP,ORMDL2,COX7A2L,LAMTOR4,ZDHHC7,SIL1,DTD1,UNC13C,BCCIP,SART1,TRAF7,NDUFAF2,TOR1AIP1,ZNF416,LAGE3,ZFYVE21,RRAGC,ZNF121,OIP5,NRF1,WDR44,ABRAXAS2,PPME1,PIN1,RPAP1,AHCYL1,TOP1MT,LMAN1,STRAP,SPSB3,ZNF583,SNX25,ARHGAP17,POLR2G,ZNF780B,PPT1,NUP155,DCLRE1C,MRPS14,RHBDF2,SUGP1,AFDN,RBL1,UBXN2B,STK38,FASTK,AP1S1,SPRYD4,H3F3A,CHID1,SMAD4,RAD51D,SLC30A9,UNK,CMAS,NADSYN1,AGO2,HMGN3,NCAPG,SCYL2,FZD6,GTPBP3,HERC3,CTSS,ORC3,YTHDC1,ACP2,HMGN5,CSRP1,PRKDC,ABCF2,TUFM,RANGAP1,PNPLA8,HAGH,API5,ZFR,SEC23IP,E2F1,USP20,RBPJ,PDCD6IP,MAX,LUZP1,ADAM10,TSC22D3,CXXC1,AP3M2,CUL1,NANS,GYG1,OAT,MYEF2,ANKRD26,MTFR1L,PA2G4,NOL11,FIZ1,ZNF200,AP2B1,FBXW2,MARCH2,SRSF10,SRP72,KLF10,LACTB,SUPT20H,CBFB,RFC2,RAB2B,PRIM1,MAP3K4,HHEX,BRD2,LUC7L3,RPS14,MAP4,MRPL27,BTF3,PTPDC1,SLF1,NMD3,CCDC59,PTOV1,COX5B,DNAJC5,SCOC,DHPS,POLR2K,PRKAA1,VAV2,GSPT2,TATDN3,PXMP2,PRPF39,PSEN1,ZNF79,PDXDC1,VPS25,NDUFS7,YY1AP1,C12orf10,FAM192A,RPN1,LHX8,ARPC5,ZNRF2,TPST1,DAPK1,CYC1,MRM3,FDFT1,SOCS5,GID8,PIGT,CPQ,WDR1,ZNF574,C1orf35,EXOSC9,ARID1A,FXR1,PTTG1IP,GOSR1,MAP2K2,TWISTNB,AKAP1,HMGN2,XRCC5,PI4K2A,DERL1,CAT,SEC31A,MTHFD2,HSPBP1,CEBPG,ARAP1,USP32,FAM83D,CABIN1,SMPD4,GPI,CYTIP,TP53RK,REPS2,RAB11B,UROD,SLC39A13,POMP,BCL2L1,NUDT19,DECR1,SIAH1,RALB,LPIN2,ADCY9,MRPS27,SOCS6,TTC3,RNASEH2A,CFL1,ANKLE2,CDC123,VDAC2,EDF1,EML4,ERC1,ANKZF1,RAD51C,ZNF282,DSN1,DDOST,HINT1,DGCR8,RAB24,SAFB,FTSJ1,NCLN,BEND3,EYA2,DYNC1LI2,MANBA,B4GALT5,FAM76A,TKT,CBLL1,ARGLU1,LANCL1,POFUT1,HEATR5B,HLA-A,EBP,RFWD3,NDUFA2,FUT8,PTPN11,MRPL54,FEM1B,RPL19,CNN2,NDUFA3,MTX2,MSH6,PDLIM2,RFXANK,FBXO9,GUF1,SPPL2B,RPL32,ZHX1,OAZ2,NDUFS5,WDR91,HIGD2A,GPR89B,RORB,POLA2,ZBED3,ZNF76,MTX3,COPA,KMT2E,UQCR10,HMGXB3,ABCB10,COMMD5,ATP5PF,MAP1LC3B,DST,RAB35,SIVA1,GPATCH1,TCEA1,CARMIL1,DRAM2,TRAPPC13,DEAF1,SNRNP200,LAP3,NCK1,VHL,SREK1,ARHGDIB,PITPNB,HSPB11,BRWD1,PPM1G,SH3GLB2,CRCP,BAZ1B,CAB39,STK11,CHEK2,CLU,CHPT1,MRPL13,DCAF5,CAPN1,UBE2D3,NSMCE4A,PPP1R12A,GORASP1,ZCCHC8,UBXN1,NACA,RPL15,PCSK7,EPN1,THRAP3,TTF1,QSOX2,NUP205,PRPF18,CHKA,DTL,MED10,PYURF,ZRANB1,MCPH1,ATP6V0D1,CSNK1G3,ATP5IF1,CREG1,ERLIN1,NUDT4,RPL6,VKORC1,SLTM,EVC2,KLHL15,SIAH2,SLC16A1,DNPH1,SNRNP70,EHD4,C11orf1,APOL2,N4BP2L2,CHMP2A,SNX27,CORO7,FEZ2,PMS2,UCK2,UCK1,CLCC1,EXT2,MXD1,USP5,HNRNPA2B1,SAP130,NVL,PPP6C,CYB5R1,UTP4,ZNF770,EBAG9,RNF25,PCGF6,FAM72B,PON2,VPS26C,HNRNPR,HPS5,STAT6,MAPK1,PDF,TMEM33,NAT14,DNAJC2,TRIP12,SHPRH,SCYL1,VPS45,MYO9B,GFM2,SPPL2A,FASTKD3,FGFR3,MZT2A,GRK2,KMT5A,PPIG,NABP2,ZDHHC13,H2AFY,NDUFS8,ATG13,FBL,FRMD8,SLC35A1,MICAL3,TGFB1,B3GALT6,ELOVL5,PPP1R9B,HEMK1,TIMMDC1,PSPC1,HELB,MIER1,NADK2,NDRG3,CDK11A,MTMR3,KMT2B,ACAT1,CENPT,PLOD3,RAB3IL1,ZSWIM6,RAB14,ADD1,MRPS15,KDM4A,XIAP,DHX8,GLUD1,ANKRD23,PABPC4,CDK5,CALM2,PSMD1,NEK6,NSRP1,RABGAP1L,SRSF4,FNIP2,SPATC1L,PCBP2,KCNAB2,MLST8,PLK3,ZNF672,MRPL43,HSDL1,MCL1,TOPORS,PPFIA3,SMC2,ICMT,SLC50A1,STOML2,ZNF689,LIMK1,PRDX5,ATE1,VIPAS39,MLYCD,ST3GAL2,ATP6V0C,FBXL3,TFDP2,E2F2,AAAS,PFKP,SSRP1,DDX42,MRPL9,MRPS2,STRN4,TOP2B,TMED3,RAVER2,DDRGK1,GNS,INTS7,MCM5,PHF14,RTCB,ZNF326,UBE2QL1,NAGPA,CYFIP1,TIMM8B,ETV3,TSPYL4,DHX29,MAN1B1,TEX10,RPS10,CBFA2T2,ABCF1,RHOB,SCARB2,OSBPL11,CCDC86,CSK,DUSP3,MDH1,SLAIN1,HEXA,SNX14,RNF139,SGF29,ZNF296,FAM208B,TRERF1,UBR2,ACTR3,CHD1L,WDTC1,MYH9,CREBL2,NIPA2,SAFB2,PRKACA,STAM,ANKIB1,RAB21,SP100,ZKSCAN1,DDA1,NUP107,ANKRD13C,CEP63,MAVS,RBM15,ATF2,DCTN1,SHOC2,PSRC1,MAP4K4,INTS13,WBP2,ATP6V0A1,NUSAP1,NDUFA7,DNAJA1,TAZ,TAF2,SEC61A1,RPLP1,WDR7,RBMS1,FUS,GEN1,COIL,LRP8,LRCH1,ZNF786,GALK1,RPS2,SESTD1,TRAK1,JMJD6,SIKE1,AKT1S1,KRI1,FBXO3,ERH,GATC,NDUFB4,PPP1R8,PRDM4,DCP1A,GEMIN6,GTSE1,SGCB,S100A6,IMPA2,NUDC,PDPK1,MOB4,TK1,GUK1,TNFAIP3,GALC,ZNF512,MRPS10,DDX39A,RPA1,ZNF180,ZNF862,KEAP1,POLE,TATDN2,PITX1,CAPN7,PML,LRPPRC,HMGB2,USF2,ANAPC4,SRM,DDX47,MCCC1,CDC42SE2,CDIPT,SEC16A,KCMF1,SSR1,LIN9,PCNA,ZNF639,ETV6,TRMU,PIK3R2,TXLNA,PPCDC,MYBL1,CCAR1,MRPL32,BAZ2A,PBXIP1,TLK1,MRPL12,EZR,LRP5,BRCA1,PRKRA,STX16,OPTN,EPB41,SEPT1,SOCS4,QRSL1,DHFR2,PIEZO1,OSGEPL1,NUDT11,GLCCI1,NAA60,GEMIN7,SEPHS2,LZTR1,RACGAP1,PPP3CB,B4GALT4,RLF,RAPGEF6,SNRNP25,RB1,VASP,MED8,TIGAR,VMP1,PPIL2,MEA1,TIMELESS,TMEM8A,ALDH18A1,PREB,ABCC1,TRAPPC9,AACS,MEMO1,RTF1,KRAS,UBE4B,NFATC2IP,ARPC1A,ZNF174,PSMC4,GOLGA4,SYNCRIP,PALB2,NIPA1,RNF114,TIGD2,FOXM1,XAB2,MRPL39,SUMO2,DUSP22,COMMD8,RPL11,CSDE1,MDM2,CORO1A,MINPP1,GM2A,DVL2,POC5,PSMA8,COQ10B,CPOX,TIGD5,SLC26A6,PRPF3,TXNL4A,RPSA,SRSF1,DNAJC10,ZNF700,SCAP,TOMM6,TIMM17A,LTA4H,AP2S1,INTS2,CTDP1,MIF4GD,CDT1,ARID5A,SUMF1,GGA2,CSNK1A1,AP3S1,RMI1,TFRC,PTPN2,STARD9,IRF4,GSTK1,NDUFV1,SLC1A4,CWC27,SLC35B4,ABCD1,DDX31,RPAP3,CNTN5,SNX2,ZMYM5,BORA,CHCHD6,CDKN2AIPNL,FBXO41,KPNA4,BIRC5,TFE3,SNAP29,CDCA7L,PKD2,ACADM,CHMP7,SAT2,GCSH,ZNF496,TMEM109,TAP1,YTHDF3,NHLRC3,IKBIP,KIFC1,DBNDD1,CYB5RL,PARPBP,CDC25B,MAST2,DNMT1,NOL12,USO1,AKT2,NOL8,GNG7,ELOA,MRNIP,AURKB,MCFD2,SLC25A5,ZFAND5,MAK16,STT3A,TMED10,PSMD8,EIF2D,PTPN7,ITGB1,UQCRH,RRS1,ARRB2,RTN3,SVIP,DDX58,WSB2,PPIB,MUT,GMFG,HLA-E,NDUFA4,MAN2B1,METTL3,NDUFS4,CFLAR,RNF121,MEX3C,KLF16,DAD1,HDAC7,BDH1,PCYT2,GNAI2,ANKHD1,TERF2,MORC3,NOA1,SEPT8,KCTD20,DCTD,TOMM40,PKM,PATL1,PSMB3,ADSS,SERTAD2,SERF2,NSF,ZFP92,DCK,ERGIC3,ACLY,LPCAT4,VCPIP1,PPP6R3,MAP3K5,PPP6R2,YY1,CDK2,RNF14,ZC3HAV1,SYS1,ZBTB37,URB2,EIF3D,MAGED1,KLHL18,ADPGK,SLC25A44,AP1B1,SDHA,PAIP2,MOAP1,PHC2,TERF2IP,CRKL,CYHR1,ZNF75D,SHC1,UCHL5,NAA35,TMBIM1,MRM2,CDKN2AIP,CCT2,MKLN1,HMGN4,LYRM1,GALK2,CDC23,AP4E1,SHCBP1,PRDM11,VEZF1,PPP2R5A,GUCY1B1,STAT1,PPA2,TRIM32,RHEBL1,R3HCC1L,MRI1,TCF3,BRAP,MYNN,AGPAT3,SDF2L1,SPR,RAB11A,REEP5,FOXO3,MAD2L2,PIP5K1C,MAT2B,RBM17,PTEN,CENPJ,TAGLN2,OSTC,CREB1,MAP3K14,NCOA2,PACS2,SMC4,RNASEH2C,NET1,NEK7,PARP4,TBRG4,ANAPC2,RPL27A,YIF1A,SGSH,HGS,TTLL4,ATP5MC3,MFAP1,CCDC69,BRWD3,ESYT2,NPHP4,SKA3,ST13,HNRNPAB,DNAJC24,ZNF107,SIRT2,AGFG1,KIF2C,SNRPD3,UBQLN2,FKBP2,USP48,CUTC,EDC3,UBLCP1,ZNF804A,RAP1A,THADA,EIF4A3,AP3S2,ATG3,DPYSL2,PPP1R12C,AKR1B1,JOSD1,NDUFB9,RP2,TTC4,TECR,ARID4A,FGFR1OP2,TIMM50,TDP1,DPM1,FOPNL,SLC25A22,WDR82,STK17B,DHX15,CHAF1A,GEMIN5,TIMM29,COPS6,SASS6,RPS26,PSMC1,TBC1D12,TM9SF4,ZNF768,UFC1,MED13L,TIA1,MEF2A,EPHX2,PITHD1,RHBDD1,NFATC3,BANF1,ZNF335,BUD31,YBX1,KNTC1,UBE3C,ACAD8,ALDH9A1,KDELR1,ZNF189,TSTA3,CIC,OXR1,PSMA1,SEPT7,NAP1L1,NSMF,ODF2,EXOC4,TRMT10B,NUP62,PITPNA,NAA20,MZT2B,PDSS2,PTDSS1,TMEM106C,ASH1L,IMMT,CHERP,WDYHV1,PLAGL2,IRF3,CHKB,TWF2,PAIP1,ANKRD28,FARSA,ANKLE1,SAR1A,APOOL,PDIA6,ACSL5,CGAS,DMAC2,TOR1AIP2,AZI2,GFER,RAD54B,DAP3,ZNF317,GADD45B,AKNA,REEP4,CBX4,MIF,KIF3B,GOLPH3L,CASP6,TOR3A,SRGN,DBF4,TIMM21,MFSD10,SAC3D1,CTNNBL1,YIF1B,TTC17,SLC25A1,GINS1,TELO2,CSNK1G2,HMGN1,ADAM17,NASP,ASPM,PRKAR1B,ATP5MF,SYMPK,SNRPA,TARS,HSPA1B,MAPK3,CNOT9,HLA-B,PLAA,ATAD2,OSBPL8,ZNF330,KBTBD7,PREPL |
| 2.733e-128 | -293.73 | intracellular membrane-bounded organelle | cellular component | GO:0043231 | 10742 | 2140 | 18223 | 2701 |
HECA,ZBTB10,ABCC10,HEXB,TGOLN2,CCNL2,SYNRG,FBXO22,RAD23B,ATP13A3,DNM2,ZNRD1,FTSJ3,ERCC1,NRAS,EHMT1,HNRNPF,WDHD1,MIER2,DIDO1,MCM2,MID1IP1,SMAD2,RPS27A,MYO18A,OGT,MPV17,COX5A,SMAD1,ZNF75A,ANXA11,SLC25A33,GGA1,SEC61G,CCZ1,MUM1,RAB23,KCTD17,APH1B,PARN,CDC73,TMEM179B,SMC3,TNPO3,GEMIN4,MVP,NUP85,PABPC1,NSUN4,PPP6R1,IFRD1,AGGF1,RBM42,FOXK1,GTPBP4,MRPL16,ELK1,RDH11,MAGED2,KPNA1,ETS2,WIPI2,ACSF2,FAM72D,EXOC3,RHOG,VTI1A,STARD7,INO80E,SLC35B2,RCOR3,LCLAT1,CPNE3,RBM23,AHCTF1,ZNF420,TBC1D14,GMEB1,NSFL1C,ZNF226,ZC3H3,PDCL3,SNX8,ERMP1,EID1,IDH3A,POLR2D,HTATIP2,MEF2D,TMEM147,GSTCD,NSMCE2,CAMKMT,PPP5C,PITRM1,TUBB,COMMD10,ZNF445,SRSF6,CCM2,HABP4,FLOT1,ABHD14B,ATG2B,ATP5F1B,HDGFL2,NEXMIF,TUT4,PPP1R3B,GOLM1,ZBTB45,HUWE1,ZNF260,NAA50,KANSL2,NAP1L4,ST8SIA2,ZNF710,MED22,SPTAN1,STAU1,DDX24,TACC1,USP42,MRS2,LDHA,HEBP2,LLPH,RAB3IP,PICALM,SH3BP5,PARG,ACOX1,FAM3C,AEN,PARP10,YWHAH,THAP5,TRIM11,YTHDC2,RBM8A,SNX15,ENSA,NENF,SND1,RUFY1,TRIM65,PRNP,KRR1,RAB8A,NUP210,NOC2L,EIF5,RYBP,PTPN18,MIOS,SNRPB,CDC6,PBRM1,UTP3,USP21,TRAM2,GRIPAP1,NUMB,ZNF564,FUBP1,PARP12,ZCCHC9,CENPF,LAMTOR3,CHCHD2,RSAD1,SUB1,MBD2,SSBP3,XPA,AHCY,RBM3,GLE1,MRPL48,NSDHL,ZNF761,METTL22,APPL1,RXRB,SDHB,PCM1,GALNT2,NLRC5,RUVBL2,BTBD10,CCNB2,ECPAS,USP7,GLT8D1,SUCLG1,ARID2,TMX4,SLC2A1,ATP6V1B2,LYN,PCBP1,BCAP31,MRPL50,PSMA6,ZNF473,KMT5C,BRPF3,ZNF302,TARDBP,BCAP29,SPIDR,CTDSP2,PRPF19,PPIF,KDM3B,MND1,CLCN3,BIRC3,RAB7A,PPIE,CHMP2B,VDAC1,TMEM201,GLOD4,IDE,DHX16,UHRF2,CHMP4B,XRCC3,BCL2L12,NIFK,C19orf53,MCM10,MTERF1,TMX3,CDCA8,GTF3A,ARF1,CDK11B,PAGR1,TUBGCP2,DNAJB9,POLR1B,RNF5,RBM15B,PPAN,RHOA,RPRD1A,BTAF1,TOP3A,PCGF1,DDX23,RAB18,TRIM26,PDCD6,NEK1,ATP6V1D,L3MBTL3,NEIL3,CTBS,BBX,IMPDH1,TAF12,NR2F2,PGAM1,HIPK3,IFI16,TXN,NUP188,PNISR,H2AFZ,TMEM203,PRKCSH,USP39,UBE2I,PARK7,SLC25A37,GLMP,RAB4A,TRA2B,SUCLG2,TAF5L,CISD2,SMARCE1,ZNF800,CDC5L,ZNF524,SGCE,NSUN2,USP22,CLNS1A,EIF3A,ZMYM3,DOT1L,IWS1,MKNK1,KIF18B,TPP2,C1orf109,ZMAT3,FAM72C,B4GALT2,PRPF38B,RECQL,C9orf78,EWSR1,GADD45G,RRM1,ACAP1,B4GALT1,CYCS,SUPT7L,ZNF518A,TMEM165,WDR48,CNOT3,NPLOC4,TMEM250,EXOSC7,LRRC8D,MSH2,PIGG,MRPL40,TNRC18,APOL1,EIF5A,GCC2,PRIM2,ELL2,COQ8A,RDH10,MFNG,USF3,RPS24,GORASP2,ADRB2,CCT8,PHF6,PFDN5,GOLGA2,EPOP,RBMX,MED15,PIAS2,APPL2,SAMD8,CDKN2A,NUDT3,ZNF511,NDC1,ATXN3,RAF1,C2orf49,CD320,EPM2A,CCNA2,BRI3,TAP2,AQR,TP53BP2,CDK12,ILKAP,SAP30,BRD4,DRAP1,NARF,ELP4,ABHD11,PKMYT1,SERP1,TRIM28,SUPT16H,EIF3K,CHMP4A,CERS6,ATF6,XRCC4,PRPF4B,NDUFS1,DEPDC1,MECP2,SECISBP2,SPDL1,HMG20A,WWP2,SLC25A36,CCNK,DNAJC8,ELP5,AXIN2,CARF,CITED2,KAT2A,ANKRD37,TMEM126B,PACS1,BMS1,KCNQ1,ARSK,MACF1,KLF6,COMMD4,KIF11,FADD,SH3GLB1,SMAP2,CBX3,PPP1R11,DUSP11,DDX5,WDR62,TAF6,ESPL1,PURA,DEF6,IPO4,FAM83G,DDB1,CCNC,PIGM,LYRM4,PTP4A3,UBE2Q1,BRIX1,MRPL19,ZNF696,SF3B2,PCYOX1L,CDC42,GOT2,JAZF1,HADHB,RPF2,SLC35C2,CARM1,SRPK2,WDR41,LARS,LRBA,RIOX2,SUMF2,KMT2C,OGFR,MPC1,ASF1B,MAN2A2,EIF4ENIF1,NIP7,U2SURP,MIA2,ZNF268,VPS4A,PM20D2,XPNPEP3,RGS2,LYAR,EI24,POLR2I,SUGP2,GBA,SYVN1,DAPK3,MASTL,UAP1,NFIL3,YWHAZ,CTSA,TMEM14A,TOB1,TSEN15,ADNP2,TCF12,PRKAB1,MDH2,SMARCA4,ORC1,RRN3,UBXN2A,CD3EAP,KIF14,EXOSC1,CS,CLTB,CSTF1,CHP1,POU2AF1,UBQLN4,NXT1,SMU1,LSM8,ATXN1,GLO1,BICD2,OGDH,EDEM2,TOLLIP,FANCE,MBD3,RPS9,PDHX,ALKBH6,SURF4,ARNTL,ANP32E,FKBP5,ABCA1,CWC25,ZNF316,RAE1,NUP54,CHIC2,PAWR,MXD4,DCUN1D4,PIP4K2A,XPR1,KLHL20,SEC24C,RRBP1,DUS2,ARHGEF2,ANP32A,STAT3,MYO5A,TXNL1,COA3,PHF20L1,DCAF6,ATP2C1,RFFL,COG1,RCOR1,PRMT2,TFEB,LEMD2,CTSL,UPF1,ZC3H7B,ZMIZ1,HRAS,TERF1,SLF2,CCDC93,TMED7,FGFR1OP,MAP3K7CL,PIGQ,AGPAT1,PPP1R16B,EDRF1,MIS12,CIPC,PDS5B,NUP153,SENP1,PGAP2,TMEM115,AATF,PLEKHF2,BRMS1,TRIM47,PWWP2B,WDR11,AXIN1,LONP2,NDUFV2,PHF23,EZH1,LMNA,DDX56,EIF2S2,FOXN2,CARS2,RB1CC1,PRRC2A,ZMYND11,PGS1,MYBL2,SRSF5,MPG,MATR3,CYB5A,NCDN,POLR2J,SETD3,TEX30,CNOT6,EGLN1,ZNF207,ANKRD27,ABCA3,SARNP,IVNS1ABP,RMI2,TMEM97,NUF2,RXYLT1,ZNF267,TCF19,KTN1,APP,CLUAP1,PRKD3,ATP2A2,UTP18,GRSF1,DUT,ANAPC7,FAM76B,CLN6,GCC1,TMEM9,RNF169,ATP6V1G1,RNPS1,CDCA2,FKBP3,DDX17,CHCHD3,PEX5,CDC16,HIPK2,MBOAT1,TICAM1,PDXK,ZBTB11,TMBIM4,ANXA6,GMCL1,UBE4A,ETS1,WRB,PNO1,ZNF92,CAPN2,ADD3,SUV39H2,TPCN1,TMX1,HNRNPM,LYPLA2,MFSD12,PPP3CA,POLK,JTB,PDE3B,KIF18A,WNT5B,MAPK6,SLC25A19,PSAP,WDR76,FAF1,SNAPIN,COX15,AGRN,THOC1,GPBP1L1,PPP1R15B,CSNK2A1,EBNA1BP2,BIRC2,GIT2,ATPAF1,XRCC2,ZFYVE27,MCMBP,PTPRK,SP3,METTL1,EXOSC6,HARS,ESYT1,ANLN,RAB5B,RHEB,TBC1D17,CDCA4,TIMM13,TONSL,NRM,NAGLU,ACTB,ZNF45,SINHCAF,TMUB1,CTCF,ASAH1,ASXL2,CRLF3,NUS1,CMTR2,SLC27A4,MDFIC,AFF1,MAML1,CYTH1,NQO2,UTP15,ZDHHC3,SPATA33,MOSPD3,CDC27,SNAP23,TBPL1,PRMT7,ATP5F1A,NDUFA5,UGP2,DYNLL1,COPE,HCFC1R1,ZADH2,RPAIN,RAD23A,SEC11A,PDK2,ATP6V0B,ZBTB21,STRBP,TNFAIP8,MRPL34,PDCD2,SAP30L,RPL35,BTG2,DNAJC9,MTMR6,NFATC2,KDM1B,USP36,MRPL2,ATP1A1,CLK3,MAFK,PSMD3,NDUFA11,ZNF436,DNAJC17,NCOA1,SLC25A39,ZC3HC1,ZNF146,SMAP1,GOLIM4,CDC40,SMC6,ARFIP2,NKRF,WRNIP1,SS18L1,CENPM,PTGES3,CAMK2G,MLEC,ZNF202,PPWD1,FAM50B,RHOT2,NEU1,GOLGA7,PGRMC1,GLG1,SPCS3,UBE2C,NDUFB6,ZDHHC8,CCNB1,COMMD6,POLR3K,RIC1,C14orf119,UTP25,SNUPN,ASAP2,TFG,SPTSSA,SEH1L,ATG9A,PBK,ARHGAP45,MKI67,DDX20,GALNT7,SLC17A5,AMDHD2,CCNF,FOXRED1,RBM47,WDR4,DHTKD1,SARAF,HDAC2,PWWP2A,HSPH1,MAPRE1,LIME1,CHTF18,ADO,KIF23,SLC35B1,PMF1,NOTCH2,COPG2,JMY,NDUFAF6,FKBP1A,SLC25A51,ATP6V0A2,PIKFYVE,LPCAT1,EEF1D,TMED2,FTL,PHF10,DDX28,ZNF84,SIGMAR1,PIP4K2C,CYFIP2,KDM3A,SF3A2,FAS,ZNF777,CSNK1G1,QARS,DCAF11,PPP3R1,TCOF1,NRBP1,CABLES1,DNMT3A,TRIP10,RPS6KA1,SF3B1,CAST,SUZ12,GPR89A,RAC1,OLA1,SNN,GNB2,SDE2,FLAD1,APLP2,KDM2A,CDKN1B,TNPO2,TALDO1,GPX4,ATP13A1,RFC3,ERF,TAOK1,CUL3,SLBP,POLG2,PSMB9,H2AFV,GAR1,DHX57,CENPU,SOCS7,NSA2,HSPA4,JAK1,MRPL55,TBL3,FAAP100,GOLGA8A,H2AFX,SEL1L,B4GALT3,PDCD11,CSNK1D,ATMIN,POLQ,POU3F2,NCOR2,SCAMP3,TWNK,BABAM1,SLC25A12,BLM,GTF2F1,RPL17,CRAT,AHSA1,PRC1,UPF2,SLC38A10,COPS7B,CNOT6L,CNPY3,UBE2M,TSHZ1,ZFP64,STRIP1,DENND1B,WDR18,ILF3,RHOT1,MARK2,TSR2,ECH1,PRDX1,POLR2A,NUCB1,PLD3,PFDN4,PRDX3,HNRNPH3,CCZ1B,STX18,TFDP1,NAXE,KHSRP,ASNA1,CPEB2,BYSL,VPS29,S100PBP,DDX52,ADA2,PTMS,IER2,NOP2,UBN1,NF1,ALKBH5,MOGS,UBE2Z,TAF6L,MAPK14,BECN1,SNAPC4,RNF103,BCAT2,MBD4,CYREN,CMSS1,METTL14,IMPAD1,PHTF1,SRI,KHDC4,KIF22,ZBTB22,NFU1,OGG1,TRIM14,ELOF1,COPS8,FYTTD1,TRIM8,SOX4,PAF1,UBTF,SPATA2,ATXN2L,PQBP1,IARS2,GALNT10,ROCK1,STARD3NL,RPS15,PIGN,AGTRAP,CDIP1,CIB1,XPO7,SRRT,APOPT1,ZNF449,KIFAP3,BCL2,HP1BP3,ISG15,CAND1,TSC1,RBM25,CDCA5,ZFP90,RBBP4,NIPSNAP2,HNRNPDL,ZBTB24,SMARCD1,MBD1,TOMM20,FAM92A,IFI27L1,MPHOSPH8,GNPNAT1,HNRNPUL2,NSD3,CHD1,MEAF6,MIEF1,BABAM2,AKAP8,PARL,RPN2,CHTOP,F2R,ABI1,TMEM14C,SCYL3,HTRA2,RLIM,MOSPD1,FAM172A,ZNF500,PSMB7,NLN,BOLA1,ERBIN,NDUFB1,BUD13,PEF1,EIF3G,TAB2,TULP3,CHCHD1,WDR59,CANT1,SCARB1,USP11,SMURF1,CDS2,MRPL42,EYA1,CDK2AP2,MRPS26,LETMD1,KLF13,MAN1A1,FBXO5,PELO,BRD7,MRPL11,SAMD4B,ZDHHC18,GTF3C6,POLR3GL,WDR81,MEN1,ZNF407,MFN2,COX8A,ZRANB2,SRSF3,MBD6,ATP6V1C1,TATDN1,IDH3B,TSC2,LACTB2,RBM4,CMTM6,ZNF275,RPL23A,CDKN2C,USF1,NAPG,AP1M1,MECR,UPRT,CRY2,ECD,MOB1A,RNF26,LRRC59,TIPARP,RHBDD2,MGAT5,MRPL57,BAK1,ZNF559,RHOBTB3,GABPA,NUTF2,COA7,GINS4,ARF4,BOLA3,AHNAK,RAD18,RNASEL,CHPF2,OAZ1,SMNDC1,PDCD4,NXT2,HIVEP3,CLSPN,RHOC,DHX9,PDCD7,PSMD9,COPB2,CD59,TFAP4,RNFT1,RBM34,MEGF8,EFTUD2,FBXO7,MYDGF,CPSF4,MRPL21,LUC7L2,SRSF11,EIF3L,MAPKAPK3,MTA2,ERO1A,SF3B6,MTFR2,SSR2,USP10,ITM2A,BCLAF1,MTX1,SFXN5,TXNDC16,CFAP20,ZNF830,MRPL3,NUP58,ALS2,FAM72A,KARS,TRIM41,GGNBP2,ANK3,PTTG1,TPX2,DAZAP2,GLRX3,SH3BP1,MTA1,UBA5,CLCN6,NABP1,INTS12,MICU2,RPRD1B,CGGBP1,CPNE1,SEC61B,POLR2L,FAM118B,KAT7,GOPC,CIRBP,E2F3,CRNKL1,PFKFB3,GORAB,RAB1A,KIF2A,PPP2CA,LSM6,RNF38,SNRPG,DMWD,CENPBD1,USP13,ZFP91,TRMT6,IP6K2,WDR5,SLC25A43,PMVK,IFT27,NEIL2,SAPCD2,RRP36,RPA2,PSMD2,CLIC4,PDCD10,COQ4,ARF5,GTF2H2,UTP20,MAGT1,GPS2,DBI,SSNA1,WDR13,FANCI,CREM,PAPOLA,FANCL,TET3,GLIS2,TIMM23,INTS1,POP7,SLC44A1,MTPN,RPP25,PLK1,APH1A,RBX1,RAD51AP1,ZBED5,PSMG1,UBE2V1,EAF2,KRTCAP2,LUC7L,LSG1,ALG3,AGPAT2,CHD3,E2F4,ZNF367,KPNA2,PRPF4,BEND6,CLN3,NGLY1,FAM208A,POT1,CCDC137,RMND5A,HJURP,NEMP2,PHB2,DNAJB2,SDC2,CDK13,COX4I1,DNAJB1,RAB6A,CNOT11,ARID1B,C1GALT1,MLX,ZNF746,ARL6IP1,CTR9,ICE2,NIPSNAP1,DCAF8,LDB1,ACSL3,NPIPA1,RMC1,IRF5,NMT2,RBM38,RPL36,HAUS8,MBIP,PAXX,ORMDL2,LAMTOR4,COX7A2L,SIL1,ZDHHC7,DTD1,BCCIP,SART1,TRAF7,NDUFAF2,TOR1AIP1,ZNF416,LAGE3,RRAGC,ZNF121,OIP5,NRF1,ABRAXAS2,WDR44,PPME1,PIN1,RPAP1,AHCYL1,TOP1MT,LMAN1,STRAP,ZNF583,SNX25,ARHGAP17,POLR2G,PPT1,ZNF780B,NUP155,DCLRE1C,MRPS14,RHBDF2,AFDN,SUGP1,RBL1,STK38,FASTK,UBXN2B,AP1S1,SPRYD4,H3F3A,SMAD4,CHID1,RAD51D,SLC30A9,CMAS,AGO2,HMGN3,NCAPG,SCYL2,GTPBP3,CTSS,ORC3,YTHDC1,ACP2,HMGN5,CSRP1,PRKDC,ABCF2,TUFM,RANGAP1,PNPLA8,API5,HAGH,ZFR,SEC23IP,E2F1,RBPJ,PDCD6IP,MAX,LUZP1,ADAM10,CXXC1,TSC22D3,AP3M2,CUL1,GYG1,OAT,MYEF2,MTFR1L,PA2G4,NOL11,FIZ1,ZNF200,AP2B1,MARCH2,SRSF10,SRP72,KLF10,LACTB,SUPT20H,RFC2,CBFB,RAB2B,PRIM1,HHEX,BRD2,LUC7L3,RPS14,MRPL27,PTPDC1,BTF3,SLF1,NMD3,CCDC59,PTOV1,COX5B,DNAJC5,SCOC,POLR2K,PRKAA1,TATDN3,PXMP2,PRPF39,PSEN1,ZNF79,VPS25,PDXDC1,YY1AP1,NDUFS7,FAM192A,C12orf10,RPN1,LHX8,ZNRF2,TPST1,CYC1,MRM3,FDFT1,GID8,PIGT,CPQ,ZNF574,EXOSC9,ARID1A,FXR1,PTTG1IP,GOSR1,MAP2K2,TWISTNB,XRCC5,PI4K2A,HMGN2,AKAP1,CAT,SEC31A,DERL1,MTHFD2,CEBPG,ARAP1,USP32,CABIN1,GPI,SMPD4,CYTIP,TP53RK,UROD,SLC39A13,BCL2L1,POMP,NUDT19,DECR1,RALB,SIAH1,LPIN2,MRPS27,TTC3,RNASEH2A,CFL1,ANKLE2,VDAC2,EDF1,ERC1,ANKZF1,RAD51C,ZNF282,DDOST,HINT1,DSN1,DGCR8,RAB24,SAFB,NCLN,BEND3,EYA2,DYNC1LI2,MANBA,B4GALT5,FAM76A,TKT,CBLL1,ARGLU1,POFUT1,HLA-A,HEATR5B,EBP,RFWD3,NDUFA2,FUT8,PTPN11,FEM1B,MRPL54,NDUFA3,MTX2,MSH6,PDLIM2,RFXANK,GUF1,SPPL2B,ZHX1,OAZ2,NDUFS5,GPR89B,HIGD2A,POLA2,RORB,ZNF76,COPA,MTX3,KMT2E,HMGXB3,UQCR10,ABCB10,COMMD5,ATP5PF,MAP1LC3B,DST,SIVA1,RAB35,GPATCH1,TCEA1,CARMIL1,DRAM2,DEAF1,SNRNP200,LAP3,NCK1,VHL,SREK1,PITPNB,BRWD1,PPM1G,SH3GLB2,BAZ1B,CRCP,STK11,CLU,CHEK2,MRPL13,CHPT1,DCAF5,CAPN1,UBE2D3,NSMCE4A,PPP1R12A,GORASP1,ZCCHC8,UBXN1,NACA,RPL15,EPN1,PCSK7,THRAP3,TTF1,QSOX2,NUP205,PRPF18,DTL,MED10,PYURF,ZRANB1,MCPH1,ATP6V0D1,CSNK1G3,ATP5IF1,CREG1,NUDT4,ERLIN1,RPL6,VKORC1,SLTM,EVC2,KLHL15,SIAH2,SLC16A1,DNPH1,SNRNP70,EHD4,C11orf1,APOL2,N4BP2L2,CHMP2A,SNX27,CORO7,PMS2,CLCC1,EXT2,MXD1,USP5,SAP130,HNRNPA2B1,NVL,PPP6C,CYB5R1,ZNF770,UTP4,EBAG9,RNF25,PCGF6,FAM72B,PON2,VPS26C,HNRNPR,STAT6,MAPK1,PDF,TMEM33,NAT14,DNAJC2,TRIP12,SHPRH,SCYL1,VPS45,GFM2,SPPL2A,FASTKD3,FGFR3,MZT2A,PPIG,KMT5A,NABP2,ZDHHC13,H2AFY,NDUFS8,ATG13,FBL,SLC35A1,MICAL3,TGFB1,B3GALT6,PPP1R9B,ELOVL5,HEMK1,TIMMDC1,PSPC1,HELB,MIER1,NADK2,CDK11A,ACAT1,KMT2B,CENPT,PLOD3,RAB14,ADD1,MRPS15,KDM4A,XIAP,DHX8,GLUD1,ANKRD23,PABPC4,CDK5,CALM2,PSMD1,NEK6,NSRP1,RABGAP1L,SRSF4,PCBP2,MLST8,PLK3,ZNF672,HSDL1,MRPL43,TOPORS,MCL1,SMC2,ICMT,SLC50A1,STOML2,LIMK1,ZNF689,PRDX5,MLYCD,VIPAS39,ATE1,ATP6V0C,ST3GAL2,TFDP2,FBXL3,E2F2,PFKP,AAAS,SSRP1,DDX42,MRPL9,MRPS2,TOP2B,TMED3,DDRGK1,RAVER2,GNS,INTS7,MCM5,PHF14,ZNF326,RTCB,UBE2QL1,NAGPA,TIMM8B,ETV3,TSPYL4,DHX29,TEX10,MAN1B1,RPS10,CBFA2T2,ABCF1,RHOB,SCARB2,OSBPL11,CCDC86,DUSP3,MDH1,HEXA,RNF139,SNX14,SGF29,ZNF296,FAM208B,TRERF1,UBR2,CHD1L,WDTC1,MYH9,CREBL2,PRKACA,SAFB2,RAB21,SP100,ZKSCAN1,DDA1,NUP107,ANKRD13C,MAVS,RBM15,ATF2,DCTN1,SHOC2,PSRC1,INTS13,WBP2,ATP6V0A1,NUSAP1,NDUFA7,DNAJA1,TAZ,TAF2,SEC61A1,RBMS1,FUS,GEN1,COIL,ZNF786,RPS2,TRAK1,JMJD6,AKT1S1,FBXO3,KRI1,GATC,NDUFB4,PPP1R8,PRDM4,GEMIN6,GTSE1,DCP1A,S100A6,NUDC,MOB4,PDPK1,TNFAIP3,GALC,ZNF512,MRPS10,DDX39A,RPA1,ZNF180,ZNF862,KEAP1,POLE,TATDN2,CAPN7,PITX1,PML,LRPPRC,HMGB2,USF2,ANAPC4,DDX47,MCCC1,CDIPT,SEC16A,SSR1,LIN9,PCNA,ZNF639,ETV6,PIK3R2,TRMU,MYBL1,CCAR1,MRPL32,BAZ2A,PBXIP1,TLK1,MRPL12,EZR,LRP5,BRCA1,PRKRA,STX16,OPTN,EPB41,QRSL1,DHFR2,PIEZO1,OSGEPL1,NUDT11,NAA60,GEMIN7,LZTR1,RACGAP1,PPP3CB,B4GALT4,RLF,SNRNP25,RB1,MED8,TIGAR,VMP1,PPIL2,TIMELESS,TMEM8A,ALDH18A1,PREB,ABCC1,TRAPPC9,MEMO1,RTF1,KRAS,UBE4B,NFATC2IP,ZNF174,PSMC4,GOLGA4,SYNCRIP,PALB2,TIGD2,RNF114,FOXM1,XAB2,MRPL39,SUMO2,DUSP22,COMMD8,RPL11,CSDE1,MDM2,CORO1A,MINPP1,GM2A,DVL2,POC5,PSMA8,COQ10B,CPOX,TIGD5,SLC26A6,PRPF3,TXNL4A,RPSA,SRSF1,DNAJC10,SCAP,ZNF700,TIMM17A,TOMM6,LTA4H,AP2S1,INTS2,CTDP1,MIF4GD,CDT1,ARID5A,SUMF1,GGA2,CSNK1A1,AP3S1,RMI1,PTPN2,GSTK1,STARD9,IRF4,NDUFV1,CWC27,SLC35B4,DDX31,ABCD1,SNX2,ZMYM5,CHCHD6,CDKN2AIPNL,KPNA4,BIRC5,SNAP29,TFE3,CDCA7L,PKD2,ACADM,CHMP7,GCSH,ZNF496,TMEM109,TAP1,NHLRC3,IKBIP,KIFC1,CYB5RL,PARPBP,CDC25B,DNMT1,NOL12,USO1,AKT2,NOL8,ELOA,MRNIP,AURKB,MCFD2,SLC25A5,MAK16,STT3A,TMED10,PSMD8,EIF2D,PTPN7,UQCRH,RRS1,ARRB2,RTN3,SVIP,PPIB,MUT,HLA-E,NDUFA4,MAN2B1,METTL3,NDUFS4,RNF121,MEX3C,KLF16,DAD1,HDAC7,BDH1,PCYT2,GNAI2,TERF2,MORC3,NOA1,TOMM40,PKM,PATL1,PSMB3,SERTAD2,SERF2,NSF,ZFP92,DCK,ERGIC3,ACLY,LPCAT4,VCPIP1,PPP6R3,MAP3K5,PPP6R2,YY1,CDK2,RNF14,ZC3HAV1,SYS1,ZBTB37,URB2,MAGED1,ADPGK,SLC25A44,AP1B1,SDHA,MOAP1,PHC2,TERF2IP,CRKL,CYHR1,ZNF75D,SHC1,UCHL5,TMBIM1,MRM2,CDKN2AIP,CCT2,HMGN4,LYRM1,CDC23,AP4E1,PRDM11,VEZF1,PPP2R5A,STAT1,PPA2,TRIM32,R3HCC1L,TCF3,MRI1,BRAP,MYNN,AGPAT3,SDF2L1,SPR,RAB11A,REEP5,FOXO3,MAD2L2,PIP5K1C,MAT2B,RBM17,PTEN,CENPJ,MAP3K14,CREB1,OSTC,NCOA2,PACS2,SMC4,RNASEH2C,NET1,NEK7,PARP4,TBRG4,ANAPC2,RPL27A,YIF1A,SGSH,HGS,ATP5MC3,MFAP1,CCDC69,BRWD3,ESYT2,NPHP4,HNRNPAB,ZNF107,SIRT2,AGFG1,KIF2C,SNRPD3,UBQLN2,FKBP2,USP48,CUTC,UBLCP1,ZNF804A,THADA,EIF4A3,AP3S2,AKR1B1,NDUFB9,RP2,TECR,ARID4A,TIMM50,TDP1,DPM1,FOPNL,SLC25A22,WDR82,STK17B,DHX15,CHAF1A,GEMIN5,TIMM29,COPS6,RPS26,PSMC1,TBC1D12,TM9SF4,ZNF768,MED13L,TIA1,MEF2A,EPHX2,PITHD1,RHBDD1,NFATC3,BANF1,ZNF335,BUD31,YBX1,KNTC1,UBE3C,ACAD8,KDELR1,ZNF189,CIC,OXR1,PSMA1,SEPT7,NAP1L1,NSMF,ODF2,NUP62,NAA20,MZT2B,PDSS2,PTDSS1,TMEM106C,ASH1L,IMMT,CHERP,WDYHV1,PLAGL2,IRF3,ANKRD28,ANKLE1,SAR1A,APOOL,PDIA6,ACSL5,DMAC2,TOR1AIP2,GFER,RAD54B,DAP3,ZNF317,GADD45B,AKNA,REEP4,CBX4,MIF,GOLPH3L,CASP6,TOR3A,SRGN,DBF4,TIMM21,CTNNBL1,YIF1B,SLC25A1,GINS1,TELO2,CSNK1G2,HMGN1,NASP,ASPM,ATP5MF,SYMPK,SNRPA,HSPA1B,MAPK3,CNOT9,HLA-B,PLAA,ATAD2,OSBPL8,ZNF330,PREPL |
| 1.076e-122 | -280.84 | intracellular | cellular component | GO:0005622 | 14533 | 2557 | 18223 | 2701 |
HECA,ZBTB10,ABCC10,HEXB,TGOLN2,CCNL2,SYNRG,FBXO22,EEF2K,RAD23B,ATP13A3,DNM2,ZNRD1,FTSJ3,USP34,ERCC1,NRAS,EHMT1,KIF15,HNRNPF,WDHD1,MIER2,DIDO1,MCM2,RAB22A,MID1IP1,SMAD2,RPS27A,MYO18A,OGT,MPV17,COX5A,KLHL42,SMAD1,ZNF75A,ANXA11,SLC25A33,ZNF720,GGA1,SEC61G,CCZ1,MUM1,TRIO,RAB23,KCTD17,HAUS4,EIF2AK4,APH1B,PARN,CDC73,MYL6B,ATG4A,TMEM179B,PDXP,SMC3,TNPO3,GEMIN4,MVP,NUP85,PABPC1,NSUN4,PPP6R1,PPA1,IFRD1,AGGF1,RBM42,FOXK1,GTPBP4,MAP7D1,MRPL16,ELK1,EIF4H,RDH11,MAGED2,KPNA1,ETS2,TYW5,WIPI2,RUFY3,PDLIM5,ACSF2,FAM72D,EXOC3,RHOG,VTI1A,C5orf30,STARD7,SLC35B2,INO80E,RCOR3,LCLAT1,CPNE3,KIAA1147,RBM23,AHCTF1,ZNF420,TBC1D22A,TBC1D14,GMEB1,NSFL1C,SEPT11,ZNF226,GPD1L,ZC3H3,ARL5A,PDCL3,SNX8,ERMP1,EID1,IDH3A,NBPF11,POLR2D,HTATIP2,MEF2D,TMEM147,GSTCD,MAT2A,VPS26B,CORO1C,NSMCE2,CAMKMT,PPP5C,PITRM1,TUBB,COMMD10,ZNF445,SRSF6,CCM2,HABP4,FLOT1,ABHD14B,ATG2B,ATP5F1B,HDGFL2,NEXMIF,TUT4,PPP1R3B,GOLM1,ZBTB45,HUWE1,ZNF260,NAA50,ANXA5,LTN1,KANSL2,UBE3B,NAP1L4,ST8SIA2,ZNF710,RPL22L1,MED22,SPTAN1,STAU1,DDX24,TCTEX1D2,TACC1,USP42,MRS2,LDHA,HEBP2,LLPH,RAB3IP,PICALM,SH3BP5,PARG,ACOX1,FAM3C,AEN,PARP10,YWHAH,WDR45B,THAP5,FAM129A,TRIM11,YTHDC2,RBM8A,SNX15,ENSA,NENF,SND1,RUFY1,TRIM65,ZER1,PRNP,KRR1,RAB8A,NUP210,NOC2L,EIF5,TACC3,RYBP,PTPN18,MIOS,SNRPB,CDC6,PBRM1,UTP3,ODC1,USP21,TRAM2,FBXO28,GRIPAP1,ARRDC1,DVL1,NUMB,ZNF564,FUBP1,CTU2,PARP12,ZCCHC9,CENPF,LAMTOR3,CHCHD2,NCKAP1,RSAD1,TNS3,SUB1,RINL,MBD2,SSBP3,KIF13B,XPA,AHCY,RBM3,GLE1,MRPL48,LRSAM1,NSDHL,AMD1,CAMSAP1,ZNF761,METTL22,STYXL1,APPL1,BBS12,RXRB,SDHB,PCM1,GALNT2,TMEM168,NLRC5,RUVBL2,BTBD10,MYO9A,ECPAS,CCNB2,USP7,GLT8D1,RPLP2,SUCLG1,ARID2,TMX4,SLC2A1,ATP6V1B2,LYN,PCBP1,BCAP31,MRPL50,VAV1,PSMA6,ZNF473,KMT5C,BRPF3,ZNF302,TARDBP,BCAP29,SPIDR,CTDSP2,PRPF19,PPIF,KDM3B,MND1,CLCN3,BIRC3,RAB7A,PPIE,CHMP2B,VDAC1,TMEM201,EIF3H,GLOD4,IDE,DHX16,UHRF2,CHMP4B,XRCC3,PARD3,BCL2L12,NIFK,C19orf53,MCM10,MTERF1,KLHL21,PDAP1,TMX3,CDCA8,GTF3A,ARF1,CDK11B,PAGR1,TUBGCP2,DNAJB9,HOMER1,POLR1B,RNF5,RBM15B,PPAN,RHOA,RPRD1A,BTAF1,TOP3A,ARHGEF12,PCGF1,DDX23,RAB18,TRIM26,PDCD6,NEK1,ATP6V1D,FAM110A,L3MBTL3,NEIL3,CTBS,BBX,IMPDH1,TAF12,NR2F2,PGAM1,ARHGAP23,HIPK3,IFI16,TXN,NUP188,PNISR,H2AFZ,TMEM203,PRKCSH,USP39,UBE2I,PARK7,SLC25A37,GLMP,RAB4A,TRA2B,SUCLG2,CISD2,TAF5L,SMARCE1,ZNF800,CDC5L,ZNF524,SGCE,NSUN2,USP22,CLNS1A,EIF3A,ZMYM3,DOT1L,IWS1,MKNK1,WAS,KIF18B,TPP2,C1orf109,ZMAT3,FAM72C,B4GALT2,PRPF38B,RECQL,C9orf78,EWSR1,GADD45G,RRM1,DNAAF5,ACAP1,B4GALT1,CYCS,FAM136A,SUPT7L,ZNF518A,TMEM165,WDR48,SPAG5,NPLOC4,CNOT3,RTKN,TMEM250,CEP104,EXOSC7,KLHL5,LRRC8D,PPP4R1,MSH2,PIGG,OSTF1,FBXL7,MRPL40,TNRC18,SYTL3,APOL1,EIF5A,GCC2,PRIM2,ELL2,COQ8A,RDH10,USF3,MFNG,RPS24,GORASP2,CAPZA2,ADRB2,MTR,CCT8,PHF6,PFDN5,GOLGA2,EPOP,RBMX,MED15,PIAS2,APPL2,SAMD8,CDKN2A,NUDT3,ZNF511,NDC1,ATXN3,RAF1,C2orf49,CD320,EPM2A,CCNA2,MTMR4,BRI3,TAP2,AQR,TP53BP2,CDK12,ILKAP,SAP30,BRD4,DRAP1,NARF,LRRC8A,ELP4,ABHD11,PKMYT1,ASB13,SERP1,TRIM28,SUPT16H,EIF3K,CHMP4A,CERS6,ATF6,XRCC4,PRPF4B,NDUFS1,DEPDC1,MECP2,SECISBP2,SPDL1,HMG20A,WWP2,JAKMIP1,SLC25A36,CCNK,DNAJC8,ELP5,AXIN2,CARF,CITED2,KAT2A,ANKRD37,TMEM126B,RABIF,ADSL,PACS1,BMS1,KCNQ1,OTUD3,ARSK,MACF1,KLF6,COMMD4,KIF11,FADD,SH3GLB1,SMAP2,MYO1F,CBX3,SELENOW,INF2,TMEM127,PPP1R11,DUSP11,DDX5,WDR62,TAF6,ESPL1,PURA,DEF6,FAM83G,IPO4,DDB1,UBL3,CCNC,PIGM,LYRM4,PTP4A3,UBE2Q1,BRIX1,MRPL19,ZNF696,SF3B2,PCYOX1L,CDC42,SYNM,GOT2,JAZF1,HADHB,RPF2,SLC35C2,CARM1,SRPK2,WDR41,LARS,LRBA,RIOX2,TMEM216,SUMF2,KMT2C,OGFR,MPC1,ASF1B,RPL37,MAN2A2,EIF4ENIF1,NIP7,U2SURP,MIA2,ZNF268,VPS4A,ATP6V0E1,PPP1R2,PM20D2,XPNPEP3,RGS2,LYAR,EI24,FAM89B,POLR2I,SUGP2,GBA,SYVN1,EIF2A,DAPK3,ARHGAP15,MASTL,UAP1,NFIL3,FN3KRP,YWHAZ,CTSA,TMEM14A,TOB1,TSEN15,ADNP2,TCF12,PRKAB1,MDH2,SMARCA4,ORC1,RRN3,UBXN2A,IARS,CD3EAP,KIF14,EXOSC1,CS,CLTB,DNAL4,CSTF1,CHP1,POU2AF1,UBQLN4,PPP1R18,NXT1,PGGT1B,SMU1,ATXN1,LSM8,GLO1,BICD2,OGDH,EDEM2,TOLLIP,FANCE,MBD3,RPS9,PDHX,ALKBH6,DUS3L,SURF4,ARNTL,ANP32E,FKBP5,CCDC125,PDCD2L,ABCA1,CWC25,GCLM,ZNF316,RAE1,DCTN2,NUP54,CHIC2,PAWR,MXD4,DCUN1D4,PIP4K2A,XPR1,FERMT3,KIF5B,KLHL20,SEC24C,RRBP1,DUS2,ARHGEF2,ANP32A,STAT3,MYO5A,AMPD2,TXNL1,COA3,PHF20L1,DCAF6,FAM49B,ATP2C1,RFFL,COG1,RCOR1,PRMT2,TFEB,LEMD2,CTSL,UPF1,ELMO1,ZC3H7B,DTX4,ZMIZ1,HRAS,TERF1,SLF2,CCDC93,TMED7,FGFR1OP,MAP3K7CL,PIGQ,AGPAT1,CNTROB,PPP1R16B,MIEN1,EDRF1,MIS12,CIPC,GSDMB,PDS5B,NUP153,SENP1,PGAP2,TMEM115,AATF,DCUN1D5,PLEKHF2,BRMS1,TRIM47,PWWP2B,WDR11,AXIN1,SMG9,TRIM52,LONP2,NDUFV2,PHF23,CERK,EZH1,ITGB5,LMNA,MCTS1,DDX56,EIF2S2,FOXN2,CARS2,RB1CC1,PRRC2A,ZMYND11,PGS1,MYBL2,SRSF5,MPG,MATR3,CYB5A,NCDN,POLR2J,SETD3,TEX30,PTAR1,CNOT6,NDE1,EGLN1,ZNF207,ANKRD27,ABCA3,SARNP,IVNS1ABP,RMI2,TMEM97,MON1B,NUF2,RXYLT1,NIT2,ZNF267,TCF19,KTN1,APP,CLUAP1,PRKD3,ATP2A2,UTP18,GRSF1,DUT,ZCCHC2,ANAPC7,FAM76B,RNF19A,CLN6,GCC1,TMEM9,RNF169,ATP6V1G1,ADCY7,ENPP4,RNPS1,CDCA2,FKBP3,DDX17,CHCHD3,PEX5,CDC16,HIPK2,NT5C3B,MBOAT1,TICAM1,PDXK,ZBTB11,TMBIM4,ANXA6,GMCL1,UBE4A,ETS1,WRB,PLPP5,PNO1,ZNF92,CAPN2,ADD3,SUV39H2,TPCN1,TMX1,HNRNPM,LYPLA2,MFSD12,LDHB,PPP3CA,POLK,JTB,MTMR12,ZP3,PDE3B,CIP2A,KIF18A,CCDC6,WNT5B,MAPK6,C4orf46,SLC25A19,RGL1,PSAP,WDR76,IGBP1,FAF1,SNAPIN,COX15,AGRN,THOC1,GPBP1L1,GNPDA1,PPP1R15B,CSNK2A1,EBNA1BP2,BIRC2,GIT2,ATPAF1,ABL2,DLG5,XRCC2,ZFYVE27,MCMBP,PTPRK,CDC37,METTL1,SP3,EXOSC6,HARS,GMFB,CYSTM1,ESYT1,ANLN,RAB5B,RHEB,DPYSL3,TBC1D17,CDCA4,TIMM13,TONSL,NRM,NAGLU,ACTB,ZNF45,SINHCAF,C2CD5,TMUB1,CTCF,ASAH1,DOCK11,ASXL2,CRLF3,LRRC14,NUS1,CMTR2,SLC27A4,MDFIC,AFF1,MAML1,CYTH1,NQO2,UTP15,EIF2AK1,EIF4G2,ZDHHC3,SPATA33,MOSPD3,CDC27,SNAP23,TBPL1,PRMT7,ATP5F1A,KCTD7,NDUFA5,CYLD,UGP2,DYNLL1,COPE,HCFC1R1,ZADH2,GGPS1,RPAIN,ABRACL,RAD23A,SEC11A,PDK2,ATP6V0B,ZBTB21,STRBP,TNFAIP8,DUS4L,MRPL34,PDCD2,SAP30L,RPL29,TIMP2,RPL35,BTG2,TUBGCP5,FRAT2,DNAJC9,MTMR6,NFATC2,KDM1B,ARL5B,USP36,MRPL2,ATP1A1,CLK3,MAFK,PSMD3,NDUFA11,CEP55,ZNF436,DNAJC17,NCOA1,SLC25A39,ZC3HC1,ZNF146,SMAP1,GOLIM4,CDC40,GNE,SMC6,ARFIP2,NKRF,CHAC2,BZW2,WRNIP1,SS18L1,CENPM,PTGES3,CAMK2G,MLEC,ZNF202,PPWD1,FAM50B,RHOT2,NEU1,GOLGA7,PGRMC1,GLG1,FAM126A,SPCS3,RPS6KC1,UBE2C,PPCS,NDUFB6,ZDHHC8,CCNB1,COMMD6,POLR3K,ABHD14A,RIC1,C14orf119,UTP25,SNUPN,ASAP2,TFG,PLCL2,SPTSSA,SEH1L,ATG9A,PBK,ARHGAP45,MKI67,DDX20,GALNT7,SLC17A5,AMDHD2,CCNF,FOXRED1,RBM47,WDR4,DHTKD1,SARAF,TRAF5,HDAC2,PWWP2A,HSPH1,MAPRE1,LIME1,CHTF18,ADO,KIF23,SLC35B1,PMF1,NOTCH2,COPG2,JMY,NDUFAF6,FKBP1A,SLC31A1,SNX18,ATIC,CTPS1,SLC25A51,ATP6V0A2,RNF135,PIKFYVE,LPCAT1,EEF1D,TMED2,FTL,PHF10,DDX28,ZNF84,SIGMAR1,PIP4K2C,PLEC,RIT1,CYFIP2,KDM3A,SF3A2,FAS,EPRS,ZNF777,CSNK1G1,QARS,DCAF11,PPP3R1,TCOF1,NRBP1,CABLES1,DNMT3A,RWDD1,TRIP10,RPS6KA1,SF3B1,CAST,SUZ12,GPR89A,RAC1,OLA1,SNN,GNB2,SDE2,FLAD1,APLP2,KDM2A,CDKN1B,TNPO2,TALDO1,GPX4,ATP13A1,RFC3,MAPRE2,ERF,TAOK1,CUL3,SLBP,POLG2,PSMB9,H2AFV,GAR1,DHX57,CENPU,SOCS7,NSA2,HSPA4,JAK1,MRPL55,TBL3,FAAP100,GOLGA8A,H2AFX,SEL1L,B4GALT3,PDCD11,CSNK1D,ATMIN,POLQ,POU3F2,OTUD5,NCOR2,ANKRD13D,PKP4,SCAMP3,TWNK,BABAM1,CDCA3,SLC25A12,BLM,GTF2F1,RPL17,CRAT,AHSA1,PRC1,UPF2,SLC38A10,COPS7B,CNOT6L,CNPY3,IFT46,UBE2M,TSHZ1,ZFP64,STRIP1,DENND1B,DENND4C,WDR18,ILF3,RPL8,LRRC1,RHOT1,MARK2,TSR2,ECH1,PRDX1,POLR2A,FBXO21,NUCB1,GNA12,PLD3,C1orf131,PFDN4,PRDX3,HNRNPH3,CCZ1B,STX18,TFDP1,NAXE,KHSRP,ASNA1,CPEB2,BYSL,VPS29,S100PBP,DDX52,MIB2,ADA2,PTMS,IER2,NOP2,UBN1,NF1,DCAF15,ALKBH5,MOGS,UBE2Z,TAF6L,MAPK14,BECN1,SNAPC4,RNF103,BCAT2,MBD4,CYREN,CMSS1,METTL14,IMPAD1,RCSD1,PHTF1,SRI,KHDC4,KIF22,ZBTB22,NFU1,OGG1,TRIM14,ELOF1,COPS8,FYTTD1,TRIM8,RRM2,SOX4,ABHD5,PAF1,UBTF,CXXC4,SPATA2,ATXN2L,PQBP1,IARS2,GALNT10,ROCK1,STARD3NL,CEP170B,RPS15,PIGN,AGTRAP,CDIP1,CIB1,XPO7,SRRT,APOPT1,ZNF449,CAPZA1,KIFAP3,BCL2,GLTP,N4BP2,HP1BP3,VOPP1,ISG15,CAND1,GNAS,TSC1,RBM25,CDCA5,ZFP90,RBBP4,NANP,NIPSNAP2,HNRNPDL,ZBTB24,SMARCD1,WASF2,MBD1,MMACHC,TOMM20,FAM92A,IFI27L1,MPHOSPH8,GNPNAT1,HNRNPUL2,NSD3,CHD1,MEAF6,MIEF1,BABAM2,CCDC50,AKAP8,PARL,RPN2,CHTOP,F2R,ABI1,SCYL3,TMEM14C,HTRA2,RLIM,MOSPD1,FAM172A,ZNF500,PSMB7,NLN,WIPF1,BOLA1,ERBIN,NDUFB1,BUD13,PEF1,EIF3G,BTBD1,TAB2,TULP3,CHCHD1,WDR59,CANT1,SCARB1,GAS2,USP11,SMURF1,PPP2R2D,CDS2,MAGEH1,MRPL42,EYA1,CDK2AP2,MRPS26,LETMD1,KLF13,HDDC2,RGS1,MAN1A1,FBXO5,GART,PELO,TANK,BRD7,MRPL11,SAMD4B,ZDHHC18,GTF3C6,POLR3GL,WDR81,MEN1,ZNF407,MFN2,COX8A,ZRANB2,SRSF3,MBD6,ATP6V1C1,TATDN1,IDH3B,TSC2,LACTB2,CMTM6,RBM4,ZNF275,RPL23A,CDKN2C,NAPG,USF1,DNAAF2,MECR,AP1M1,UPRT,CRY2,ECD,MOB1A,RNF26,LRRC59,TIPARP,ANKRD9,RHBDD2,MGAT5,MRPL57,BAK1,RHOBTB3,ZNF559,GABPA,NUTF2,COA7,ARF4,GINS4,KRIT1,BOLA3,AHNAK,RAD18,PDRG1,RNASEL,CHPF2,OAZ1,SMNDC1,PDCD4,NXT2,HIVEP3,CLSPN,RHOC,DHX9,PDCD7,PSMD9,HAUS2,COPB2,CD59,TFAP4,RNFT1,MEGF8,RIMS3,RBM34,FBXO7,EFTUD2,MYDGF,CPSF4,MRPL21,PHKG2,LUC7L2,SRSF11,EIF3L,MAPKAPK3,MTA2,MTFR2,SF3B6,ERO1A,ITM2A,SSR2,USP10,BCLAF1,MTX1,SFXN5,FNTA,PDLIM1,TXNDC16,CFAP20,ZNF830,MRPL3,NUP58,ALS2,FAM72A,KARS,TRIM41,GGNBP2,NQO1,POC1A,ANK3,PTTG1,TPX2,TBC1D13,DAZAP2,STMN1,GLRX3,REPS1,SH3BP1,MTA1,UBA5,CLCN6,NABP1,INTS12,MICU2,RPRD1B,CGGBP1,CPNE1,ULK3,SEC61B,POLR2L,FAM118B,GOPC,KAT7,CIRBP,E2F3,RPL38,CRNKL1,PFKFB3,GORAB,RAB1A,KIF2A,PPP2CA,ALDH3B1,LSM6,CCDC14,RNF38,CENPBD1,SNRPG,DMWD,USP13,MZT1,ZFP91,TRMT6,IP6K2,WDR5,SLC25A43,PMVK,IFT27,NEIL2,SAPCD2,RRP36,SRXN1,RPA2,PSMD2,PDCD10,CLIC4,COQ4,ARF5,ARHGEF1,GTF2H2,FBXL19,UTP20,MAGT1,GPS2,DBI,SSNA1,AAMDC,WDR13,FANCI,PAPOLA,CREM,TET3,FANCL,GLIS2,TIMM23,INTS1,POP7,SLC44A1,MTPN,ASB6,PLK1,RPP25,CELSR2,SEPT9,RBX1,APH1A,RAD51AP1,ZBED5,PSMG1,CKAP2L,UBE2V1,EAF2,KRTCAP2,LUC7L,LSG1,NECAP2,ALG3,TRIM4,AGPAT2,CHD3,E2F4,ZNF367,KPNA2,PRPF4,DNAJC30,BEND6,CLN3,FAM208A,NGLY1,POT1,MYL12B,CCDC137,RMND5A,HJURP,NEMP2,PHB2,DNAJB2,NKD2,SDC2,KLC1,COX4I1,CDK13,DNAJB1,RAB6A,CNOT11,ARID1B,C1GALT1,MLX,UBE2Q2,CCP110,ZNF746,ARL6IP1,CTR9,ICE2,NIPSNAP1,ABHD2,DCAF8,ACSL3,LDB1,MAP4K3,ARMC8,NPIPA1,RBM38,RMC1,IRF5,NMT2,RPL36,HAUS8,PAXX,MBIP,ORMDL2,COX7A2L,LAMTOR4,ZDHHC7,SIL1,DTD1,UNC13C,BCCIP,SART1,TRAF7,NDUFAF2,TOR1AIP1,ZNF416,LAGE3,ZFYVE21,RRAGC,ZNF121,OIP5,NRF1,WDR44,ABRAXAS2,PPME1,PIN1,RPAP1,AHCYL1,TOP1MT,LMAN1,STRAP,SPSB3,ZNF583,SNX25,ARHGAP17,POLR2G,ZNF780B,PPT1,NUP155,DCLRE1C,MRPS14,RHBDF2,SUGP1,AFDN,RBL1,UBXN2B,STK38,FASTK,AP1S1,SPRYD4,H3F3A,CHID1,SMAD4,RAD51D,SLC30A9,UNK,CMAS,NADSYN1,AGO2,HMGN3,NCAPG,SCYL2,FZD6,GTPBP3,HERC3,CTSS,ORC3,YTHDC1,ACP2,HMGN5,CSRP1,PRKDC,ABCF2,TUFM,RANGAP1,PNPLA8,HAGH,API5,ZFR,SEC23IP,E2F1,USP20,RBPJ,PDCD6IP,MAX,LUZP1,ADAM10,TSC22D3,CXXC1,AP3M2,CUL1,NANS,GYG1,OAT,MYEF2,ANKRD26,MTFR1L,PA2G4,NOL11,FIZ1,ZNF200,AP2B1,FBXW2,MARCH2,SRSF10,SRP72,KLF10,LACTB,SUPT20H,CBFB,RFC2,RAB2B,PRIM1,MAP3K4,HHEX,BRD2,LUC7L3,RPS14,MAP4,MRPL27,BTF3,PTPDC1,SLF1,NMD3,CCDC59,PTOV1,COX5B,DNAJC5,SCOC,DHPS,POLR2K,VAV2,PRKAA1,GSPT2,TATDN3,PXMP2,PRPF39,PSEN1,ZNF79,PDXDC1,VPS25,NDUFS7,YY1AP1,C12orf10,FAM192A,RPN1,LHX8,ARPC5,ZNRF2,TPST1,DAPK1,CYC1,MRM3,FDFT1,SOCS5,GID8,PIGT,CPQ,WDR1,ZNF574,C1orf35,EXOSC9,ARID1A,FXR1,PTTG1IP,GOSR1,MAP2K2,TWISTNB,AKAP1,HMGN2,XRCC5,PI4K2A,DERL1,CAT,SEC31A,MTHFD2,HSPBP1,CEBPG,ARAP1,FAM83D,USP32,CABIN1,SMPD4,GPI,CYTIP,TP53RK,REPS2,RAB11B,UROD,SLC39A13,POMP,BCL2L1,NUDT19,DECR1,SIAH1,RALB,LPIN2,ADCY9,MRPS27,SOCS6,TTC3,RNASEH2A,CFL1,ANKLE2,CDC123,VDAC2,EDF1,EML4,ERC1,ANKZF1,RAD51C,ZNF282,DSN1,DDOST,HINT1,DGCR8,RAB24,SAFB,FTSJ1,NCLN,BEND3,EYA2,DYNC1LI2,MANBA,B4GALT5,FAM76A,TKT,CBLL1,ARGLU1,LANCL1,POFUT1,HEATR5B,HLA-A,EBP,RFWD3,NDUFA2,FUT8,PTPN11,MRPL54,FEM1B,RPL19,CNN2,NDUFA3,MTX2,MSH6,PDLIM2,LONRF3,RFXANK,FBXO9,GUF1,SPPL2B,RPL32,ZHX1,OAZ2,NDUFS5,WDR91,GPR89B,HIGD2A,RORB,POLA2,ZBED3,ZNF76,MTX3,COPA,KMT2E,UQCR10,HMGXB3,ABCB10,COMMD5,ATP5PF,MAP1LC3B,DST,RAB35,SIVA1,GPATCH1,TCEA1,CARMIL1,DRAM2,TRAPPC13,DEAF1,SNRNP200,LAP3,NCK1,VHL,SREK1,ARHGDIB,PITPNB,HSPB11,BRWD1,PPM1G,SH3GLB2,CRCP,BAZ1B,CAB39,STK11,CHEK2,CLU,CHPT1,MRPL13,DCAF5,CAPN1,UBE2D3,NSMCE4A,PPP1R12A,GORASP1,ZCCHC8,UBXN1,NACA,RPL15,EPN1,PCSK7,THRAP3,TTF1,QSOX2,PRPF18,NUP205,CHKA,DTL,MED10,PYURF,ZRANB1,MCPH1,ATP6V0D1,CSNK1G3,ATP5IF1,CREG1,ERLIN1,NUDT4,RPL6,VKORC1,SLTM,EVC2,KLHL15,SIAH2,SLC16A1,DNPH1,SNRNP70,EHD4,C11orf1,APOL2,N4BP2L2,CHMP2A,SNX27,CORO7,FEZ2,PMS2,UCK2,UCK1,CLCC1,EXT2,MXD1,USP5,HNRNPA2B1,SAP130,NVL,PPP6C,CYB5R1,UTP4,ZNF770,EBAG9,RNF25,PCGF6,FAM72B,PON2,VPS26C,HNRNPR,STAT6,HPS5,MAPK1,PDF,TMEM33,NAT14,DNAJC2,TRIP12,SHPRH,SCYL1,VPS45,MYO9B,GFM2,SPPL2A,FASTKD3,FGFR3,MZT2A,GRK2,KMT5A,PPIG,NABP2,ZDHHC13,H2AFY,NDUFS8,ATG13,FBL,FRMD8,SLC35A1,MICAL3,TGFB1,B3GALT6,ELOVL5,PPP1R9B,HEMK1,TIMMDC1,PSPC1,HELB,MIER1,NADK2,NDRG3,CDK11A,MTMR3,KMT2B,ACAT1,CENPT,PLOD3,RAB3IL1,ZSWIM6,RAB14,ADD1,MRPS15,KDM4A,XIAP,DHX8,GLUD1,ANKRD23,PABPC4,CDK5,CALM2,PSMD1,NEK6,NSRP1,RABGAP1L,SRSF4,FNIP2,SPATC1L,PCBP2,KCNAB2,MLST8,PLK3,ZNF672,MRPL43,HSDL1,MCL1,TOPORS,PPFIA3,SMC2,ICMT,SLC50A1,STOML2,ZNF689,LIMK1,PRDX5,ATE1,VIPAS39,MLYCD,ST3GAL2,ATP6V0C,FBXL3,TFDP2,E2F2,AAAS,PFKP,SSRP1,DDX42,MRPL9,MRPS2,STRN4,TOP2B,TMED3,RAVER2,DDRGK1,GNS,INPP5A,INTS7,MCM5,PHF14,RTCB,ZNF326,UBE2QL1,NAGPA,CYFIP1,TIMM8B,ETV3,TSPYL4,DHX29,MAN1B1,TEX10,RPS10,CBFA2T2,ABCF1,RHOB,SCARB2,OSBPL11,CCDC86,CSK,DUSP3,MDH1,SLAIN1,HEXA,SNX14,RNF139,SGF29,ZNF296,FAM208B,TRERF1,UBR2,ACTR3,CHD1L,WDTC1,MYH9,CREBL2,NIPA2,SAFB2,PRKACA,STAM,ANKIB1,RAB21,SP100,ZKSCAN1,DDA1,NUP107,ANKRD13C,CEP63,MAVS,RBM15,ATF2,DCTN1,SHOC2,PSRC1,MAP4K4,INTS13,WBP2,ATP6V0A1,NUSAP1,DNAJA1,NDUFA7,TAZ,TAF2,SEC61A1,RPLP1,WDR7,RBMS1,FUS,GEN1,COIL,LRP8,LRCH1,ZNF786,GALK1,RPS2,SESTD1,TRAK1,JMJD6,SIKE1,AKT1S1,KRI1,FBXO3,ERH,GATC,NDUFB4,PPP1R8,PRDM4,DCP1A,GEMIN6,GTSE1,SGCB,S100A6,IMPA2,NUDC,PDPK1,MOB4,TK1,GUK1,TNFAIP3,GALC,ZNF512,MRPS10,DDX39A,RPA1,ZNF180,ZNF862,KEAP1,POLE,TATDN2,PITX1,CAPN7,PML,LRPPRC,HMGB2,USF2,ANAPC4,SRM,DDX47,MCCC1,CDC42SE2,CDIPT,SEC16A,KCMF1,SSR1,LIN9,PCNA,ZNF639,ETV6,TRMU,PIK3R2,TXLNA,PPCDC,MYBL1,CCAR1,MRPL32,BAZ2A,PBXIP1,TLK1,MRPL12,EZR,LRP5,BRCA1,PRKRA,STX16,OPTN,EPB41,SEPT1,SOCS4,QRSL1,DHFR2,PIEZO1,OSGEPL1,NUDT11,GLCCI1,NAA60,GEMIN7,SEPHS2,LZTR1,RACGAP1,PPP3CB,B4GALT4,RLF,RAPGEF6,SNRNP25,RB1,VASP,MED8,TIGAR,VMP1,PPIL2,MEA1,TIMELESS,TMEM8A,ALDH18A1,PREB,ABCC1,TRAPPC9,AACS,MEMO1,RTF1,KRAS,UBE4B,NFATC2IP,ARPC1A,ZNF174,PSMC4,GOLGA4,SYNCRIP,PALB2,NIPA1,RNF114,TIGD2,FOXM1,XAB2,MRPL39,SUMO2,DUSP22,COMMD8,RPL11,CSDE1,MDM2,CORO1A,MINPP1,GM2A,DVL2,POC5,PSMA8,COQ10B,CPOX,TIGD5,SLC26A6,PRPF3,TXNL4A,RPSA,SRSF1,DNAJC10,ZNF700,SCAP,TOMM6,TIMM17A,LTA4H,AP2S1,INTS2,CTDP1,MIF4GD,CDT1,ARID5A,SUMF1,GGA2,CSNK1A1,AP3S1,RMI1,TFRC,PTPN2,IRF4,STARD9,GSTK1,NDUFV1,SLC1A4,CWC27,SLC35B4,ABCD1,DDX31,RPAP3,CNTN5,SNX2,ZMYM5,BORA,CHCHD6,CDKN2AIPNL,FBXO41,KPNA4,BIRC5,TFE3,SNAP29,CDCA7L,PKD2,ACADM,CHMP7,SAT2,GCSH,ZNF496,TMEM109,TAP1,YTHDF3,NHLRC3,IKBIP,KIFC1,DBNDD1,CYB5RL,PARPBP,CDC25B,MAST2,DNMT1,NOL12,USO1,AKT2,NOL8,GNG7,ELOA,MRNIP,AURKB,MCFD2,SLC25A5,ZFAND5,MAK16,STT3A,TMED10,PSMD8,EIF2D,PTPN7,ITGB1,UQCRH,RRS1,ARRB2,RTN3,SVIP,DDX58,WSB2,PPIB,MUT,GMFG,HLA-E,NDUFA4,MAN2B1,METTL3,NDUFS4,CFLAR,RNF121,MEX3C,KLF16,DAD1,HDAC7,BDH1,PCYT2,GNAI2,ANKHD1,TERF2,MORC3,NOA1,SEPT8,KCTD20,DCTD,TOMM40,PKM,PATL1,PSMB3,ADSS,SERTAD2,SERF2,NSF,ZFP92,DCK,ERGIC3,ACLY,LPCAT4,VCPIP1,PPP6R2,MAP3K5,PPP6R3,YY1,CDK2,RNF14,ZC3HAV1,SYS1,ZBTB37,URB2,EIF3D,MAGED1,KLHL18,ADPGK,SLC25A44,AP1B1,SDHA,PAIP2,MOAP1,PHC2,TERF2IP,CRKL,CYHR1,ZNF75D,SHC1,UCHL5,NAA35,TMBIM1,MRM2,CDKN2AIP,CCT2,MKLN1,HMGN4,LYRM1,GALK2,CDC23,AP4E1,SHCBP1,PRDM11,VEZF1,PPP2R5A,GUCY1B1,STAT1,PPA2,TRIM32,RHEBL1,R3HCC1L,TCF3,MRI1,BRAP,MYNN,AGPAT3,SDF2L1,SPR,RAB11A,REEP5,FOXO3,MAD2L2,PIP5K1C,MAT2B,RBM17,PTEN,CENPJ,TAGLN2,OSTC,CREB1,MAP3K14,NCOA2,PACS2,SMC4,RNASEH2C,NET1,NEK7,PARP4,TBRG4,ANAPC2,RPL27A,YIF1A,SGSH,HGS,TTLL4,ATP5MC3,MFAP1,CCDC69,BRWD3,ESYT2,NPHP4,SKA3,ST13,HNRNPAB,DNAJC24,ZNF107,SIRT2,AGFG1,KIF2C,SNRPD3,UBQLN2,FKBP2,USP48,CUTC,EDC3,UBLCP1,ZNF804A,RAP1A,THADA,EIF4A3,AP3S2,ATG3,DPYSL2,PPP1R12C,AKR1B1,JOSD1,NDUFB9,RP2,TTC4,TECR,ARID4A,FGFR1OP2,TIMM50,TDP1,DPM1,FOPNL,SLC25A22,WDR82,STK17B,DHX15,CHAF1A,GEMIN5,TIMM29,COPS6,SASS6,RPS26,PSMC1,TBC1D12,TM9SF4,ZNF768,UFC1,MED13L,TIA1,MEF2A,EPHX2,PITHD1,RHBDD1,NFATC3,BANF1,BUD31,ZNF335,YBX1,KNTC1,UBE3C,ACAD8,ALDH9A1,KDELR1,ZNF189,TSTA3,CIC,OXR1,PSMA1,SEPT7,NAP1L1,NSMF,ODF2,EXOC4,NUP62,TRMT10B,PITPNA,NAA20,MZT2B,PDSS2,PTDSS1,TMEM106C,ASH1L,IMMT,CHERP,WDYHV1,PLAGL2,IRF3,CHKB,TWF2,PAIP1,ANKRD28,FARSA,ANKLE1,SAR1A,APOOL,PDIA6,ACSL5,CGAS,DMAC2,TOR1AIP2,AZI2,GFER,RAD54B,DAP3,ZNF317,GADD45B,AKNA,REEP4,CBX4,MIF,KIF3B,GOLPH3L,SH2D3A,CASP6,TOR3A,SRGN,DBF4,TIMM21,MFSD10,SAC3D1,CTNNBL1,YIF1B,TTC17,SLC25A1,GINS1,TELO2,CSNK1G2,HMGN1,ADAM17,NASP,ASPM,PRKAR1B,ATP5MF,SYMPK,SNRPA,TARS,HSPA1B,MAPK3,CNOT9,HLA-B,PLAA,ATAD2,OSBPL8,ZNF330,KBTBD7,PREPL |
| 1.075e-120 | -276.24 | intracellular organelle part | cellular component | GO:0044446 | 9030 | 1892 | 18223 | 2701 |
ZBTB10,ABCC10,HEXB,TGOLN2,LACTB2,CCNL2,SYNRG,RBM4,CMTM6,RPL23A,NAPG,USF1,RAD23B,MECR,AP1M1,DNM2,CRY2,ECD,RNF26,MOB1A,ZNRD1,LRRC59,MGAT5,RHBDD2,FTSJ3,MRPL57,BAK1,ERCC1,RHOBTB3,NRAS,GABPA,EHMT1,KIF15,HNRNPF,WDHD1,NUTF2,DIDO1,COA7,MCM2,RAB22A,GINS4,KRIT1,AHNAK,MID1IP1,SMAD2,RAD18,RPS27A,MYO18A,OGT,MPV17,COX5A,RNASEL,KLHL42,SMAD1,CHPF2,ANXA11,SMNDC1,SLC25A33,NXT2,CLSPN,GGA1,SEC61G,CCZ1,DHX9,RAB23,HAUS4,PDCD7,PSMD9,PARN,HAUS2,CDC73,MYL6B,COPB2,TMEM179B,CD59,SMC3,RNFT1,RBM34,EFTUD2,TNPO3,GEMIN4,MYDGF,MRPL21,CPSF4,MVP,NUP85,PABPC1,NSUN4,PPP6R1,LUC7L2,SRSF11,EIF3L,AGGF1,FOXK1,MAPKAPK3,MTA2,SF3B6,ERO1A,GTPBP4,USP10,SSR2,BCLAF1,MAP7D1,MRPL16,MTX1,ELK1,SFXN5,RDH11,MAGED2,FNTA,KPNA1,TXNDC16,ETS2,WIPI2,ZNF830,CFAP20,ACSF2,MRPL3,NUP58,ALS2,EXOC3,RHOG,TRIM41,KARS,POC1A,VTI1A,TPX2,STARD7,INO80E,SLC35B2,DAZAP2,STMN1,LCLAT1,CPNE3,AHCTF1,ZNF420,MTA1,TBC1D14,GMEB1,NABP1,CLCN6,NSFL1C,SEPT11,MICU2,INTS12,ZC3H3,RPRD1B,CGGBP1,SNX8,CPNE1,SEC61B,ERMP1,POLR2L,EID1,FAM118B,GOPC,KAT7,IDH3A,CRNKL1,RPL38,CIRBP,E2F3,POLR2D,HTATIP2,PFKFB3,GORAB,TMEM147,MEF2D,GSTCD,RAB1A,PPP2CA,KIF2A,ALDH3B1,LSM6,CCDC14,NSMCE2,RNF38,SNRPG,PPP5C,PITRM1,TUBB,USP13,MZT1,SRSF6,ZFP91,TRMT6,HABP4,FLOT1,ABHD14B,ATG2B,IP6K2,ATP5F1B,WDR5,IFT27,SLC25A43,NEXMIF,RRP36,SAPCD2,NEIL2,TUT4,GOLM1,RPA2,PSMD2,PDCD10,CLIC4,COQ4,HUWE1,ZNF260,KANSL2,ST8SIA2,GTF2H2,RPL22L1,MED22,SPTAN1,STAU1,TCTEX1D2,DDX24,TACC1,USP42,MRS2,HEBP2,LLPH,PICALM,UTP20,SH3BP5,MAGT1,GPS2,PARG,ACOX1,DBI,FAM3C,AEN,SSNA1,PARP10,YWHAH,WDR13,RBM8A,SNX15,ENSA,NENF,RUFY1,TRIM65,FANCI,PAPOLA,KRR1,PRNP,FANCL,RAB8A,NUP210,TIMM23,GLIS2,INTS1,SLC44A1,POP7,NOC2L,MTPN,TACC3,RYBP,PLK1,RPP25,PTPN18,SEPT9,MIOS,RBX1,APH1A,RAD51AP1,SNRPB,ZBED5,PSMG1,CKAP2L,CDC6,UBE2V1,PBRM1,EAF2,UTP3,KRTCAP2,LUC7L,USP21,LSG1,NECAP2,ALG3,FBXO28,AGPAT2,CHD3,GRIPAP1,ZNF367,E2F4,PRPF4,KPNA2,DVL1,CLN3,FAM208A,POT1,MYL12B,CCDC137,ZNF564,FUBP1,ZCCHC9,NEMP2,HJURP,PHB2,DNAJB2,CENPF,SDC2,LAMTOR3,KLC1,CHCHD2,COX4I1,CDK13,RAB6A,DNAJB1,NCKAP1,ARID1B,C1GALT1,SUB1,MLX,CCP110,MBD2,KIF13B,XPA,ARL6IP1,CTR9,ICE2,RBM3,GLE1,MRPL48,DCAF8,NSDHL,ACSL3,LDB1,CAMSAP1,METTL22,ARMC8,APPL1,NPIPA1,RMC1,HAUS8,RPL36,RXRB,SDHB,PAXX,MBIP,PCM1,GALNT2,ORMDL2,COX7A2L,LAMTOR4,NLRC5,ZDHHC7,SIL1,DTD1,RUVBL2,BTBD10,MYO9A,CCNB2,ECPAS,UNC13C,BCCIP,USP7,SART1,RPLP2,SUCLG1,ARID2,NDUFAF2,TOR1AIP1,SLC2A1,LAGE3,ZFYVE21,RRAGC,ATP6V1B2,LYN,PCBP1,BCAP31,OIP5,MRPL50,NRF1,PSMA6,ZNF473,KMT5C,BRPF3,WDR44,ABRAXAS2,PIN1,PPME1,TARDBP,BCAP29,LMAN1,TOP1MT,AHCYL1,STRAP,SPIDR,CTDSP2,PRPF19,SNX25,PPIF,KDM3B,CLCN3,BIRC3,POLR2G,PPT1,RAB7A,PPIE,NUP155,DCLRE1C,CHMP2B,VDAC1,MRPS14,RHBDF2,TMEM201,SUGP1,AFDN,IDE,DHX16,RBL1,FASTK,UHRF2,AP1S1,CHMP4B,XRCC3,H3F3A,CHID1,SMAD4,RAD51D,NIFK,CMAS,C19orf53,MCM10,MTERF1,KLHL21,PDAP1,AGO2,TMX3,CDCA8,GTF3A,HMGN3,ARF1,NCAPG,PAGR1,SCYL2,TUBGCP2,DNAJB9,FZD6,CTSS,POLR1B,ORC3,RNF5,RBM15B,YTHDC1,PPAN,ACP2,RHOA,RPRD1A,HMGN5,BTAF1,PRKDC,ABCF2,TUFM,TOP3A,RANGAP1,PNPLA8,PCGF1,HAGH,API5,DDX23,RAB18,SEC23IP,PDCD6,NEK1,ATP6V1D,FAM110A,L3MBTL3,NEIL3,BBX,E2F1,IMPDH1,USP20,RBPJ,TAF12,NR2F2,PGAM1,HIPK3,IFI16,NUP188,MAX,PDCD6IP,PNISR,H2AFZ,TMEM203,ADAM10,PRKCSH,CXXC1,AP3M2,CUL1,USP39,GYG1,UBE2I,OAT,PARK7,SLC25A37,GLMP,ANKRD26,PA2G4,NOL11,RAB4A,TRA2B,SUCLG2,AP2B1,TAF5L,CISD2,MARCH2,SMARCE1,CDC5L,SRSF10,NSUN2,SUPT20H,USP22,CBFB,RFC2,RAB2B,CLNS1A,EIF3A,PRIM1,ZMYM3,DOT1L,IWS1,MKNK1,WAS,BRD2,KIF18B,RPS14,TPP2,LUC7L3,MRPL27,MAP4,PTPDC1,SLF1,CCDC59,ZMAT3,NMD3,B4GALT2,PRPF38B,RECQL,C9orf78,COX5B,EWSR1,DNAJC5,SCOC,POLR2K,PRKAA1,RRM1,ACAP1,B4GALT1,PXMP2,CYCS,SUPT7L,PRPF39,TMEM165,PSEN1,VPS25,NDUFS7,YY1AP1,WDR48,SPAG5,NPLOC4,RTKN,C12orf10,TMEM250,RPN1,CEP104,EXOSC7,ARPC5,LRRC8D,ZNRF2,MSH2,TPST1,PIGG,FBXL7,OSTF1,MRPL40,CYC1,TNRC18,MRM3,APOL1,FDFT1,GID8,EIF5A,GCC2,PRIM2,PIGT,ELL2,COQ8A,WDR1,RDH10,USF3,MFNG,RPS24,C1orf35,EXOSC9,GORASP2,ARID1A,CAPZA2,ADRB2,PTTG1IP,FXR1,GOSR1,MAP2K2,CCT8,PHF6,TWISTNB,AKAP1,HMGN2,PI4K2A,XRCC5,DERL1,CAT,SEC31A,MTHFD2,GOLGA2,EPOP,RBMX,MED15,PIAS2,FAM83D,APPL2,ARAP1,CEBPG,CABIN1,SAMD8,SMPD4,GPI,CDKN2A,CYTIP,NDC1,ATXN3,TP53RK,RAB11B,RAF1,UROD,SLC39A13,POMP,BCL2L1,C2orf49,CD320,NUDT19,DECR1,CCNA2,MTMR4,LPIN2,MRPS27,BRI3,TAP2,TTC3,RNASEH2A,AQR,TP53BP2,CDK12,ILKAP,CFL1,SAP30,ANKLE2,BRD4,NARF,VDAC2,ELP4,EDF1,PKMYT1,ERC1,SERP1,EML4,TRIM28,SUPT16H,ANKZF1,RAD51C,CHMP4A,DSN1,HINT1,DDOST,RAB24,DGCR8,CERS6,SAFB,NCLN,ATF6,BEND3,XRCC4,EYA2,DYNC1LI2,PRPF4B,NDUFS1,B4GALT5,MANBA,MECP2,TKT,FAM76A,CBLL1,ARGLU1,SPDL1,HLA-A,EBP,SLC25A36,JAKMIP1,RFWD3,CCNK,DNAJC8,NDUFA2,FUT8,PTPN11,AXIN2,MRPL54,FEM1B,RPL19,CARF,CNN2,CITED2,NDUFA3,MTX2,MSH6,KAT2A,TMEM126B,RFXANK,BMS1,KCNQ1,ARSK,MACF1,GUF1,KLF6,KIF11,SPPL2B,SH3GLB1,MYO1F,CBX3,RPL32,ZHX1,DUSP11,DDX5,NDUFS5,WDR62,WDR91,TAF6,ESPL1,PURA,DEF6,IPO4,DDB1,HIGD2A,GPR89B,RORB,CCNC,POLA2,PIGM,LYRM4,MTX3,COPA,KMT2E,UQCR10,ABCB10,BRIX1,COMMD5,MAP1LC3B,ATP5PF,MRPL19,SF3B2,PCYOX1L,DST,CDC42,SYNM,GOT2,RAB35,SIVA1,JAZF1,HADHB,RPF2,GPATCH1,TCEA1,SLC35C2,CARMIL1,DRAM2,CARM1,SRPK2,WDR41,DEAF1,LARS,SNRNP200,LAP3,VHL,RIOX2,SREK1,SUMF2,PITPNB,KMT2C,MPC1,ASF1B,RPL37,MAN2A2,HSPB11,EIF4ENIF1,BRWD1,NIP7,U2SURP,PPM1G,MIA2,SH3GLB2,CRCP,CAB39,BAZ1B,STK11,CHEK2,CLU,VPS4A,CHPT1,MRPL13,DCAF5,ATP6V0E1,CAPN1,UBE2D3,NSMCE4A,PPP1R12A,ZCCHC8,GORASP1,UBXN1,PCSK7,RPL15,PM20D2,THRAP3,RGS2,QSOX2,TTF1,PRPF18,NUP205,LYAR,DTL,MED10,PYURF,EI24,ZRANB1,MCPH1,ATP6V0D1,ATP5IF1,POLR2I,CREG1,ERLIN1,SUGP2,RPL6,GBA,EIF2A,SYVN1,VKORC1,SLTM,DAPK3,MASTL,UAP1,SIAH2,SLC16A1,YWHAZ,CTSA,EHD4,SNRNP70,C11orf1,TMEM14A,APOL2,TSEN15,TCF12,SNX27,PRKAB1,CHMP2A,CORO7,MDH2,PMS2,SMARCA4,ORC1,EXT2,MXD1,HNRNPA2B1,SAP130,RRN3,UBXN2A,CD3EAP,NVL,KIF14,EXOSC1,PPP6C,CS,CYB5R1,CLTB,UTP4,DNAL4,EBAG9,CSTF1,CHP1,POU2AF1,UBQLN4,NXT1,SMU1,PCGF6,ATXN1,LSM8,BICD2,OGDH,EDEM2,TOLLIP,FANCE,MBD3,RPS9,PDHX,ALKBH6,SURF4,HNRNPR,STAT6,ARNTL,ANP32E,FKBP5,MAPK1,ABCA1,TMEM33,CWC25,DNAJC2,TRIP12,SHPRH,RAE1,SCYL1,DCTN2,NUP54,VPS45,PAWR,MYO9B,PIP4K2A,GFM2,FERMT3,SPPL2A,KIF5B,MZT2A,KLHL20,KMT5A,SEC24C,PPIG,RRBP1,ZDHHC13,NABP2,H2AFY,ARHGEF2,ANP32A,ATG13,NDUFS8,FBL,STAT3,SLC35A1,MICAL3,MYO5A,B3GALT6,TGFB1,ELOVL5,COA3,PPP1R9B,DCAF6,FAM49B,TIMMDC1,HELB,PSPC1,MIER1,ATP2C1,NADK2,RFFL,COG1,RCOR1,PRMT2,LEMD2,CTSL,UPF1,KMT2B,ACAT1,CENPT,ZMIZ1,PLOD3,HRAS,TERF1,SLF2,TMED7,RAB14,FGFR1OP,ADD1,KDM4A,MRPS15,PIGQ,AGPAT1,XIAP,DHX8,GLUD1,CNTROB,PPP1R16B,ANKRD23,MIS12,CALM2,CDK5,PSMD1,NEK6,NSRP1,SRSF4,PDS5B,NUP153,SPATC1L,SENP1,KCNAB2,PCBP2,MLST8,PGAP2,PLK3,ZNF672,TMEM115,AATF,MRPL43,MCL1,TOPORS,SMC2,ICMT,SLC50A1,PLEKHF2,STOML2,BRMS1,PWWP2B,WDR11,LIMK1,PRDX5,MLYCD,ST3GAL2,ATP6V0C,FBXL3,TFDP2,E2F2,LONP2,AAAS,DDX42,SSRP1,NDUFV2,MRPL9,MRPS2,PHF23,TOP2B,EZH1,TMED3,LMNA,MCTS1,DDRGK1,GNS,DDX56,INTS7,MCM5,ZNF326,RTCB,CARS2,NAGPA,CYFIP1,TIMM8B,ETV3,RB1CC1,PRRC2A,ZMYND11,PGS1,MAN1B1,TEX10,MYBL2,RPS10,SRSF5,MPG,ABCF1,MATR3,RHOB,CYB5A,SCARB2,OSBPL11,POLR2J,CCDC86,DUSP3,SETD3,NDE1,HEXA,SGF29,SNX14,RNF139,ZNF207,ANKRD27,FAM208B,ABCA3,SARNP,TRERF1,IVNS1ABP,UBR2,CHD1L,ACTR3,RMI2,TMEM97,MON1B,WDTC1,MYH9,NUF2,RXYLT1,NIT2,SAFB2,PRKACA,STAM,KTN1,APP,CLUAP1,PRKD3,RAB21,ATP2A2,SP100,UTP18,GRSF1,DUT,DDA1,NUP107,ANKRD13C,ANAPC7,FAM76B,RNF19A,CEP63,MAVS,ATF2,RBM15,CLN6,GCC1,TMEM9,RNF169,DCTN1,ATP6V1G1,ENPP4,SHOC2,PSRC1,INTS13,RNPS1,WBP2,ATP6V0A1,CDCA2,NUSAP1,DNAJA1,NDUFA7,TAZ,DDX17,TAF2,CHCHD3,PEX5,CDC16,SEC61A1,HIPK2,RPLP1,MBOAT1,TICAM1,PDXK,FUS,GEN1,ZBTB11,COIL,LRP8,RPS2,TMBIM4,ANXA6,JMJD6,GMCL1,AKT1S1,ETS1,WRB,PNO1,KRI1,FBXO3,CAPN2,ADD3,SUV39H2,NDUFB4,PPP1R8,PRDM4,GTSE1,GEMIN6,TPCN1,S100A6,TMX1,HNRNPM,LYPLA2,MFSD12,NUDC,PDPK1,MOB4,PPP3CA,GALC,POLK,JTB,MRPS10,DDX39A,RPA1,KIF18A,KEAP1,POLE,TATDN2,WNT5B,PITX1,MAPK6,LRPPRC,PML,SLC25A19,HMGB2,PSAP,USF2,ANAPC4,FAF1,SNAPIN,COX15,DDX47,AGRN,THOC1,MCCC1,CSNK2A1,EBNA1BP2,CDIPT,SEC16A,GIT2,KCMF1,SSR1,LIN9,DLG5,PCNA,ZNF639,ETV6,TRMU,XRCC2,ZFYVE27,MCMBP,MRPL32,CCAR1,SP3,METTL1,EXOSC6,PBXIP1,BAZ2A,MRPL12,CYSTM1,EZR,BRCA1,ESYT1,PRKRA,ANLN,STX16,RAB5B,RHEB,OPTN,DPYSL3,SEPT1,CDCA4,TIMM13,TONSL,NRM,NAGLU,ACTB,PIEZO1,DHFR2,ZNF45,SINHCAF,NAA60,C2CD5,GEMIN7,TMUB1,CTCF,ASAH1,RACGAP1,PPP3CB,B4GALT4,ASXL2,RAPGEF6,SNRNP25,RB1,NUS1,MED8,TIGAR,VMP1,PPIL2,SLC27A4,TIMELESS,MDFIC,AFF1,MAML1,ALDH18A1,TMEM8A,PREB,ABCC1,CYTH1,TRAPPC9,NQO2,UTP15,RTF1,ARPC1A,ZDHHC3,ZNF174,PSMC4,MOSPD3,GOLGA4,SYNCRIP,PALB2,CDC27,SNAP23,TBPL1,PRMT7,ATP5F1A,NDUFA5,CYLD,FOXM1,MRPL39,DYNLL1,XAB2,SUMO2,COPE,HCFC1R1,RPAIN,COMMD8,RPL11,RAD23A,SEC11A,ATP6V0B,PDK2,ZBTB21,MDM2,TNFAIP8,MRPL34,CORO1A,MINPP1,SAP30L,GM2A,POC5,DVL2,RPL29,TIMP2,RPL35,COQ10B,CPOX,TUBGCP5,SLC26A6,DNAJC9,MTMR6,NFATC2,PRPF3,KDM1B,TXNL4A,USP36,RPSA,SRSF1,MRPL2,DNAJC10,CLK3,SCAP,MAFK,PSMD3,TOMM6,TIMM17A,NDUFA11,CEP55,ZNF436,NCOA1,LTA4H,AP2S1,SLC25A39,ZC3HC1,ZNF146,INTS2,CTDP1,GOLIM4,CDC40,MIF4GD,CDT1,ARID5A,SMC6,ARFIP2,NKRF,SUMF1,GGA2,CSNK1A1,AP3S1,RMI1,TFRC,WRNIP1,PTPN2,STARD9,IRF4,GSTK1,NDUFV1,SLC1A4,CWC27,SLC35B4,SS18L1,ABCD1,DDX31,CENPM,PTGES3,CAMK2G,MLEC,SNX2,ZMYM5,PPWD1,FAM50B,RHOT2,CHCHD6,NEU1,CDKN2AIPNL,KPNA4,GOLGA7,BIRC5,TFE3,SNAP29,CDCA7L,PGRMC1,GLG1,PKD2,SPCS3,ACADM,UBE2C,CHMP7,GCSH,ZNF496,NDUFB6,ZDHHC8,TMEM109,TAP1,NHLRC3,CCNB1,IKBIP,POLR3K,RIC1,KIFC1,UTP25,SNUPN,ASAP2,DBNDD1,CYB5RL,PARPBP,CDC25B,TFG,SPTSSA,DNMT1,SEH1L,NOL12,USO1,ATG9A,AKT2,ARHGAP45,NOL8,ELOA,MKI67,MRNIP,DDX20,GALNT7,SLC17A5,AURKB,CCNF,MCFD2,SLC25A5,FOXRED1,MAK16,STT3A,TMED10,PSMD8,WDR4,EIF2D,PTPN7,DHTKD1,SARAF,UQCRH,RRS1,TRAF5,RTN3,HDAC2,SVIP,PPIB,HSPH1,MAPRE1,LIME1,MUT,GMFG,CHTF18,HLA-E,KIF23,NDUFA4,MAN2B1,SLC35B1,PMF1,NOTCH2,METTL3,COPG2,JMY,NDUFS4,NDUFAF6,FKBP1A,RNF121,SNX18,HDAC7,DAD1,BDH1,SLC25A51,ATP6V0A2,PCYT2,PIKFYVE,GNAI2,LPCAT1,EEF1D,TMED2,TERF2,MORC3,PHF10,FTL,DDX28,SIGMAR1,NOA1,SEPT8,PKM,TOMM40,KDM3A,PATL1,SF3A2,PSMB3,FAS,SERTAD2,NSF,QARS,ERGIC3,ACLY,DCAF11,LPCAT4,PPP3R1,VCPIP1,TCOF1,YY1,MAP3K5,PPP6R3,CDK2,NRBP1,DNMT3A,SYS1,TRIP10,RPS6KA1,SF3B1,SUZ12,URB2,GPR89A,RAC1,MAGED1,OLA1,ADPGK,SLC25A44,SNN,AP1B1,SDHA,GNB2,TERF2IP,MOAP1,PHC2,CRKL,FLAD1,CYHR1,APLP2,SHC1,KDM2A,UCHL5,TNPO2,CDKN1B,TALDO1,TMBIM1,MRM2,GPX4,CCT2,CDKN2AIP,ATP13A1,RFC3,MAPRE2,HMGN4,ERF,LYRM1,CUL3,SLBP,CDC23,POLG2,PSMB9,H2AFV,GAR1,AP4E1,SHCBP1,CENPU,NSA2,VEZF1,PPP2R5A,MRPL55,TBL3,GOLGA8A,FAAP100,H2AFX,STAT1,SEL1L,PPA2,TRIM32,B4GALT3,PDCD11,CSNK1D,ATMIN,POLQ,NCOR2,PKP4,R3HCC1L,TWNK,MRI1,TCF3,BABAM1,SLC25A12,BRAP,AGPAT3,SDF2L1,BLM,SPR,RAB11A,REEP5,FOXO3,MAD2L2,PIP5K1C,GTF2F1,RBM17,RPL17,PTEN,CENPJ,CRAT,PRC1,UPF2,COPS7B,OSTC,CREB1,MAP3K14,CNPY3,IFT46,UBE2M,NCOA2,SMC4,ZFP64,DENND1B,NEK7,DENND4C,WDR18,PARP4,ILF3,RPL8,TBRG4,ANAPC2,RHOT1,RPL27A,MARK2,POLR2A,YIF1A,NUCB1,PLD3,SGSH,HGS,ATP5MC3,TTLL4,PRDX3,HNRNPH3,CCZ1B,STX18,TFDP1,NAXE,KHSRP,CCDC69,ASNA1,BYSL,VPS29,ESYT2,S100PBP,DDX52,ADA2,IER2,NPHP4,SKA3,NOP2,HNRNPAB,UBN1,NF1,ALKBH5,MOGS,UBE2Z,KIF2C,TAF6L,SIRT2,AGFG1,SNRPD3,FKBP2,USP48,BECN1,MAPK14,SNAPC4,CUTC,RNF103,BCAT2,UBLCP1,MBD4,ZNF804A,RAP1A,THADA,EIF4A3,AP3S2,METTL14,IMPAD1,DPYSL2,RCSD1,PHTF1,SRI,AKR1B1,KHDC4,KIF22,NDUFB9,RP2,NFU1,TECR,OGG1,ARID4A,TRIM14,TIMM50,ELOF1,COPS8,FYTTD1,TRIM8,DPM1,FOPNL,WDR82,SLC25A22,SOX4,DHX15,CHAF1A,PAF1,GEMIN5,UBTF,SPATA2,TIMM29,ATXN2L,PQBP1,IARS2,ROCK1,GALNT10,COPS6,SASS6,RPS26,PSMC1,STARD3NL,CEP170B,RPS15,PIGN,AGTRAP,ZNF768,CDIP1,CIB1,MED13L,TIA1,MEF2A,XPO7,SRRT,RHBDD1,NFATC3,BANF1,CAPZA1,BUD31,ZNF335,KIFAP3,BCL2,YBX1,KNTC1,ACAD8,HP1BP3,KDELR1,VOPP1,CIC,OXR1,PSMA1,SEPT7,ISG15,CAND1,TSC1,RBM25,NSMF,CDCA5,ODF2,NUP62,RBBP4,HNRNPDL,NIPSNAP2,PTDSS1,MZT2B,PDSS2,SMARCD1,TMEM106C,MBD1,TOMM20,IMMT,ASH1L,FAM92A,MPHOSPH8,GNPNAT1,CHERP,HNRNPUL2,NSD3,IRF3,TWF2,CHD1,MEAF6,MIEF1,ANKRD28,ANKLE1,BABAM2,SAR1A,AKAP8,PARL,RPN2,APOOL,CHTOP,PDIA6,TMEM14C,HTRA2,RLIM,MOSPD1,ACSL5,FAM172A,ZNF500,DMAC2,PSMB7,NLN,WIPF1,TOR1AIP2,ERBIN,NDUFB1,BUD13,PEF1,GFER,DAP3,TAB2,TULP3,CHCHD1,WDR59,CANT1,SCARB1,GAS2,USP11,AKNA,SMURF1,REEP4,CBX4,MIF,KIF3B,CDS2,GOLPH3L,MRPL42,CASP6,EYA1,TOR3A,SRGN,CDK2AP2,MRPS26,DBF4,LETMD1,TIMM21,MFSD10,MAN1A1,SAC3D1,FBXO5,CTNNBL1,BRD7,YIF1B,MRPL11,SLC25A1,GINS1,TELO2,GTF3C6,HMGN1,NASP,ASPM,POLR3GL,WDR81,MEN1,ATP5MF,SYMPK,SNRPA,MAPK3,MFN2,HSPA1B,HLA-B,ATAD2,OSBPL8,ZNF330,COX8A,ZRANB2,SRSF3,MBD6,ATP6V1C1,TATDN1,IDH3B |
| 4.115e-114 | -261.08 | intracellular organelle | cellular component | GO:0043229 | 12479 | 2325 | 18223 | 2701 |
HECA,ZBTB10,ABCC10,HEXB,TGOLN2,CCNL2,SYNRG,FBXO22,RAD23B,ATP13A3,DNM2,ZNRD1,FTSJ3,ERCC1,NRAS,EHMT1,KIF15,HNRNPF,WDHD1,MIER2,DIDO1,MCM2,RAB22A,MID1IP1,SMAD2,RPS27A,MYO18A,OGT,MPV17,COX5A,KLHL42,SMAD1,ZNF75A,ANXA11,SLC25A33,GGA1,SEC61G,CCZ1,MUM1,RAB23,KCTD17,HAUS4,EIF2AK4,APH1B,PARN,CDC73,MYL6B,TMEM179B,PDXP,SMC3,TNPO3,GEMIN4,MVP,NUP85,PABPC1,NSUN4,PPP6R1,IFRD1,AGGF1,RBM42,FOXK1,GTPBP4,MAP7D1,MRPL16,ELK1,RDH11,MAGED2,KPNA1,ETS2,WIPI2,PDLIM5,ACSF2,FAM72D,EXOC3,RHOG,VTI1A,STARD7,SLC35B2,INO80E,RCOR3,LCLAT1,CPNE3,RBM23,AHCTF1,ZNF420,TBC1D14,GMEB1,NSFL1C,SEPT11,ZNF226,ZC3H3,PDCL3,SNX8,ERMP1,EID1,IDH3A,POLR2D,HTATIP2,MEF2D,TMEM147,GSTCD,VPS26B,CORO1C,NSMCE2,CAMKMT,PPP5C,PITRM1,TUBB,COMMD10,ZNF445,SRSF6,CCM2,HABP4,FLOT1,ABHD14B,ATG2B,ATP5F1B,HDGFL2,NEXMIF,TUT4,PPP1R3B,GOLM1,ZBTB45,HUWE1,ZNF260,NAA50,LTN1,KANSL2,NAP1L4,ST8SIA2,ZNF710,RPL22L1,MED22,SPTAN1,STAU1,DDX24,TCTEX1D2,TACC1,USP42,MRS2,LDHA,HEBP2,LLPH,RAB3IP,PICALM,SH3BP5,ACOX1,PARG,FAM3C,AEN,PARP10,YWHAH,THAP5,TRIM11,YTHDC2,RBM8A,SNX15,ENSA,NENF,SND1,RUFY1,TRIM65,PRNP,KRR1,RAB8A,NUP210,NOC2L,EIF5,TACC3,RYBP,PTPN18,MIOS,SNRPB,CDC6,PBRM1,UTP3,USP21,TRAM2,FBXO28,GRIPAP1,ARRDC1,DVL1,NUMB,ZNF564,FUBP1,PARP12,ZCCHC9,CENPF,LAMTOR3,CHCHD2,NCKAP1,RSAD1,SUB1,RINL,MBD2,SSBP3,KIF13B,XPA,AHCY,RBM3,GLE1,MRPL48,NSDHL,CAMSAP1,ZNF761,METTL22,APPL1,RXRB,SDHB,PCM1,GALNT2,TMEM168,NLRC5,RUVBL2,BTBD10,MYO9A,CCNB2,ECPAS,USP7,GLT8D1,RPLP2,SUCLG1,ARID2,TMX4,SLC2A1,ATP6V1B2,LYN,PCBP1,BCAP31,MRPL50,PSMA6,ZNF473,KMT5C,BRPF3,ZNF302,TARDBP,BCAP29,SPIDR,CTDSP2,PRPF19,PPIF,KDM3B,MND1,CLCN3,BIRC3,RAB7A,PPIE,CHMP2B,VDAC1,TMEM201,GLOD4,IDE,DHX16,UHRF2,CHMP4B,XRCC3,PARD3,BCL2L12,NIFK,C19orf53,MCM10,MTERF1,KLHL21,PDAP1,TMX3,CDCA8,GTF3A,ARF1,CDK11B,PAGR1,TUBGCP2,DNAJB9,HOMER1,POLR1B,RNF5,RBM15B,PPAN,RHOA,RPRD1A,BTAF1,TOP3A,PCGF1,DDX23,RAB18,TRIM26,PDCD6,NEK1,ATP6V1D,FAM110A,L3MBTL3,NEIL3,CTBS,BBX,IMPDH1,TAF12,NR2F2,PGAM1,HIPK3,IFI16,TXN,NUP188,PNISR,H2AFZ,TMEM203,PRKCSH,USP39,UBE2I,PARK7,SLC25A37,GLMP,RAB4A,TRA2B,SUCLG2,CISD2,TAF5L,SMARCE1,ZNF800,CDC5L,ZNF524,SGCE,NSUN2,USP22,CLNS1A,EIF3A,ZMYM3,DOT1L,IWS1,MKNK1,WAS,KIF18B,TPP2,C1orf109,ZMAT3,FAM72C,B4GALT2,PRPF38B,RECQL,C9orf78,EWSR1,GADD45G,RRM1,ACAP1,B4GALT1,CYCS,SUPT7L,ZNF518A,TMEM165,WDR48,SPAG5,NPLOC4,CNOT3,RTKN,TMEM250,CEP104,EXOSC7,KLHL5,LRRC8D,MSH2,PIGG,FBXL7,OSTF1,MRPL40,TNRC18,SYTL3,APOL1,EIF5A,GCC2,PRIM2,ELL2,COQ8A,RDH10,USF3,MFNG,RPS24,GORASP2,CAPZA2,ADRB2,CCT8,PHF6,PFDN5,GOLGA2,EPOP,RBMX,MED15,PIAS2,APPL2,SAMD8,CDKN2A,NUDT3,ZNF511,NDC1,ATXN3,RAF1,C2orf49,CD320,EPM2A,CCNA2,MTMR4,BRI3,TAP2,AQR,TP53BP2,CDK12,ILKAP,SAP30,BRD4,DRAP1,NARF,ELP4,ABHD11,PKMYT1,SERP1,TRIM28,SUPT16H,EIF3K,CHMP4A,CERS6,ATF6,XRCC4,PRPF4B,NDUFS1,DEPDC1,MECP2,SECISBP2,SPDL1,HMG20A,WWP2,JAKMIP1,SLC25A36,CCNK,DNAJC8,ELP5,AXIN2,CARF,CITED2,KAT2A,ANKRD37,TMEM126B,PACS1,BMS1,KCNQ1,ARSK,MACF1,KLF6,COMMD4,KIF11,FADD,SH3GLB1,SMAP2,MYO1F,CBX3,TMEM127,PPP1R11,DUSP11,DDX5,WDR62,TAF6,ESPL1,PURA,DEF6,FAM83G,IPO4,DDB1,CCNC,PIGM,LYRM4,PTP4A3,UBE2Q1,BRIX1,MRPL19,ZNF696,SF3B2,PCYOX1L,CDC42,SYNM,GOT2,JAZF1,HADHB,RPF2,SLC35C2,CARM1,SRPK2,WDR41,LARS,LRBA,RIOX2,TMEM216,SUMF2,KMT2C,OGFR,MPC1,ASF1B,RPL37,MAN2A2,EIF4ENIF1,NIP7,U2SURP,MIA2,ZNF268,VPS4A,ATP6V0E1,PM20D2,XPNPEP3,RGS2,LYAR,EI24,POLR2I,SUGP2,GBA,SYVN1,EIF2A,DAPK3,MASTL,UAP1,NFIL3,YWHAZ,CTSA,TMEM14A,TOB1,TSEN15,ADNP2,TCF12,PRKAB1,MDH2,SMARCA4,ORC1,RRN3,UBXN2A,CD3EAP,KIF14,EXOSC1,CS,CLTB,DNAL4,CSTF1,CHP1,POU2AF1,UBQLN4,PPP1R18,NXT1,SMU1,ATXN1,LSM8,GLO1,BICD2,OGDH,EDEM2,TOLLIP,FANCE,MBD3,RPS9,PDHX,ALKBH6,SURF4,ARNTL,ANP32E,FKBP5,ABCA1,CWC25,ZNF316,RAE1,DCTN2,NUP54,CHIC2,PAWR,MXD4,DCUN1D4,PIP4K2A,XPR1,FERMT3,KIF5B,KLHL20,SEC24C,RRBP1,DUS2,ARHGEF2,ANP32A,STAT3,MYO5A,TXNL1,COA3,PHF20L1,DCAF6,FAM49B,ATP2C1,RFFL,COG1,RCOR1,PRMT2,TFEB,LEMD2,CTSL,UPF1,ZC3H7B,ZMIZ1,HRAS,TERF1,SLF2,CCDC93,TMED7,FGFR1OP,MAP3K7CL,PIGQ,AGPAT1,CNTROB,PPP1R16B,EDRF1,MIS12,CIPC,PDS5B,NUP153,SENP1,PGAP2,TMEM115,AATF,PLEKHF2,BRMS1,TRIM47,PWWP2B,WDR11,AXIN1,LONP2,NDUFV2,PHF23,EZH1,ITGB5,LMNA,MCTS1,DDX56,EIF2S2,FOXN2,CARS2,RB1CC1,PRRC2A,ZMYND11,PGS1,MYBL2,SRSF5,MPG,MATR3,CYB5A,NCDN,POLR2J,SETD3,TEX30,CNOT6,NDE1,EGLN1,ZNF207,ANKRD27,ABCA3,SARNP,IVNS1ABP,RMI2,TMEM97,MON1B,NUF2,RXYLT1,NIT2,ZNF267,TCF19,KTN1,APP,CLUAP1,PRKD3,ATP2A2,UTP18,GRSF1,DUT,ANAPC7,FAM76B,RNF19A,CLN6,GCC1,TMEM9,RNF169,ATP6V1G1,ENPP4,RNPS1,CDCA2,FKBP3,DDX17,CHCHD3,PEX5,CDC16,HIPK2,MBOAT1,TICAM1,PDXK,ZBTB11,TMBIM4,ANXA6,GMCL1,UBE4A,ETS1,WRB,PNO1,ZNF92,CAPN2,ADD3,SUV39H2,TPCN1,TMX1,HNRNPM,LYPLA2,MFSD12,PPP3CA,POLK,JTB,PDE3B,KIF18A,CCDC6,WNT5B,MAPK6,SLC25A19,PSAP,WDR76,FAF1,SNAPIN,COX15,AGRN,THOC1,GPBP1L1,PPP1R15B,CSNK2A1,EBNA1BP2,BIRC2,GIT2,ATPAF1,ABL2,DLG5,XRCC2,ZFYVE27,MCMBP,PTPRK,METTL1,SP3,EXOSC6,HARS,CYSTM1,ESYT1,ANLN,RAB5B,RHEB,DPYSL3,TBC1D17,CDCA4,TIMM13,TONSL,NRM,NAGLU,ACTB,ZNF45,SINHCAF,C2CD5,TMUB1,CTCF,ASAH1,ASXL2,CRLF3,NUS1,CMTR2,SLC27A4,MDFIC,AFF1,MAML1,CYTH1,NQO2,UTP15,ZDHHC3,SPATA33,MOSPD3,CDC27,SNAP23,TBPL1,PRMT7,ATP5F1A,NDUFA5,CYLD,UGP2,DYNLL1,COPE,HCFC1R1,ZADH2,RPAIN,ABRACL,RAD23A,SEC11A,PDK2,ATP6V0B,ZBTB21,STRBP,TNFAIP8,MRPL34,PDCD2,SAP30L,RPL29,TIMP2,RPL35,BTG2,TUBGCP5,DNAJC9,MTMR6,NFATC2,KDM1B,USP36,MRPL2,ATP1A1,CLK3,MAFK,PSMD3,NDUFA11,CEP55,ZNF436,DNAJC17,NCOA1,SLC25A39,ZC3HC1,ZNF146,SMAP1,GOLIM4,CDC40,SMC6,ARFIP2,NKRF,WRNIP1,SS18L1,CENPM,PTGES3,CAMK2G,MLEC,ZNF202,PPWD1,FAM50B,RHOT2,NEU1,GOLGA7,PGRMC1,GLG1,SPCS3,RPS6KC1,UBE2C,NDUFB6,ZDHHC8,CCNB1,COMMD6,POLR3K,RIC1,C14orf119,UTP25,SNUPN,ASAP2,TFG,SPTSSA,SEH1L,ATG9A,PBK,ARHGAP45,MKI67,DDX20,GALNT7,SLC17A5,AMDHD2,CCNF,FOXRED1,RBM47,WDR4,SARAF,DHTKD1,TRAF5,HDAC2,PWWP2A,HSPH1,MAPRE1,LIME1,CHTF18,ADO,KIF23,SLC35B1,PMF1,NOTCH2,COPG2,JMY,NDUFAF6,FKBP1A,SLC31A1,SNX18,SLC25A51,ATP6V0A2,PIKFYVE,LPCAT1,EEF1D,TMED2,PHF10,FTL,DDX28,ZNF84,SIGMAR1,PIP4K2C,PLEC,CYFIP2,KDM3A,SF3A2,FAS,ZNF777,CSNK1G1,QARS,DCAF11,PPP3R1,TCOF1,NRBP1,CABLES1,DNMT3A,TRIP10,RPS6KA1,SF3B1,CAST,SUZ12,GPR89A,RAC1,OLA1,SNN,GNB2,SDE2,FLAD1,APLP2,KDM2A,CDKN1B,TNPO2,TALDO1,GPX4,ATP13A1,RFC3,MAPRE2,ERF,TAOK1,CUL3,SLBP,POLG2,PSMB9,H2AFV,GAR1,DHX57,CENPU,SOCS7,NSA2,HSPA4,JAK1,MRPL55,TBL3,FAAP100,GOLGA8A,H2AFX,SEL1L,B4GALT3,PDCD11,CSNK1D,ATMIN,POLQ,POU3F2,NCOR2,ANKRD13D,PKP4,SCAMP3,TWNK,BABAM1,SLC25A12,BLM,GTF2F1,RPL17,CRAT,AHSA1,PRC1,UPF2,SLC38A10,COPS7B,CNOT6L,CNPY3,IFT46,UBE2M,TSHZ1,ZFP64,STRIP1,DENND1B,DENND4C,WDR18,ILF3,RPL8,RHOT1,MARK2,TSR2,ECH1,PRDX1,POLR2A,NUCB1,PLD3,C1orf131,PFDN4,PRDX3,HNRNPH3,CCZ1B,STX18,TFDP1,NAXE,KHSRP,ASNA1,CPEB2,BYSL,VPS29,S100PBP,DDX52,MIB2,ADA2,PTMS,IER2,NOP2,UBN1,NF1,ALKBH5,MOGS,UBE2Z,TAF6L,MAPK14,BECN1,SNAPC4,RNF103,BCAT2,MBD4,CYREN,CMSS1,METTL14,IMPAD1,RCSD1,PHTF1,SRI,KHDC4,KIF22,ZBTB22,NFU1,OGG1,TRIM14,ELOF1,COPS8,FYTTD1,TRIM8,SOX4,ABHD5,PAF1,CXXC4,UBTF,SPATA2,ATXN2L,PQBP1,IARS2,GALNT10,ROCK1,STARD3NL,CEP170B,RPS15,PIGN,AGTRAP,CDIP1,CIB1,XPO7,SRRT,APOPT1,ZNF449,CAPZA1,KIFAP3,BCL2,HP1BP3,VOPP1,ISG15,CAND1,TSC1,RBM25,CDCA5,ZFP90,RBBP4,NIPSNAP2,HNRNPDL,ZBTB24,SMARCD1,WASF2,MBD1,TOMM20,FAM92A,IFI27L1,MPHOSPH8,GNPNAT1,HNRNPUL2,NSD3,CHD1,MEAF6,MIEF1,BABAM2,AKAP8,PARL,RPN2,CHTOP,F2R,ABI1,SCYL3,TMEM14C,HTRA2,RLIM,MOSPD1,FAM172A,ZNF500,PSMB7,NLN,WIPF1,BOLA1,ERBIN,NDUFB1,BUD13,PEF1,EIF3G,BTBD1,TAB2,TULP3,CHCHD1,WDR59,CANT1,SCARB1,GAS2,USP11,SMURF1,CDS2,MRPL42,EYA1,CDK2AP2,MRPS26,LETMD1,KLF13,MAN1A1,FBXO5,PELO,BRD7,MRPL11,SAMD4B,ZDHHC18,GTF3C6,POLR3GL,WDR81,MEN1,ZNF407,MFN2,COX8A,ZRANB2,SRSF3,MBD6,ATP6V1C1,TATDN1,IDH3B,TSC2,LACTB2,RBM4,CMTM6,ZNF275,RPL23A,CDKN2C,USF1,NAPG,AP1M1,MECR,UPRT,CRY2,ECD,MOB1A,RNF26,LRRC59,TIPARP,RHBDD2,MGAT5,MRPL57,BAK1,ZNF559,RHOBTB3,GABPA,NUTF2,COA7,GINS4,ARF4,KRIT1,BOLA3,AHNAK,RAD18,RNASEL,CHPF2,OAZ1,SMNDC1,PDCD4,NXT2,HIVEP3,CLSPN,RHOC,DHX9,PDCD7,PSMD9,HAUS2,COPB2,CD59,TFAP4,RNFT1,RBM34,RIMS3,MEGF8,EFTUD2,FBXO7,MYDGF,CPSF4,MRPL21,LUC7L2,SRSF11,EIF3L,MAPKAPK3,MTA2,MTFR2,SF3B6,ERO1A,ITM2A,SSR2,USP10,BCLAF1,MTX1,SFXN5,FNTA,PDLIM1,TXNDC16,CFAP20,ZNF830,MRPL3,NUP58,ALS2,FAM72A,KARS,TRIM41,GGNBP2,POC1A,ANK3,PTTG1,TPX2,DAZAP2,GLRX3,STMN1,SH3BP1,MTA1,UBA5,CLCN6,NABP1,INTS12,MICU2,RPRD1B,CGGBP1,CPNE1,SEC61B,POLR2L,FAM118B,GOPC,KAT7,CIRBP,E2F3,RPL38,CRNKL1,PFKFB3,GORAB,RAB1A,KIF2A,PPP2CA,ALDH3B1,LSM6,CCDC14,RNF38,CENPBD1,SNRPG,DMWD,USP13,MZT1,ZFP91,TRMT6,IP6K2,WDR5,SLC25A43,PMVK,IFT27,NEIL2,SAPCD2,RRP36,RPA2,PSMD2,PDCD10,CLIC4,COQ4,ARF5,GTF2H2,UTP20,MAGT1,GPS2,DBI,SSNA1,WDR13,FANCI,PAPOLA,CREM,TET3,FANCL,GLIS2,TIMM23,INTS1,POP7,SLC44A1,MTPN,PLK1,RPP25,SEPT9,RBX1,APH1A,RAD51AP1,ZBED5,PSMG1,CKAP2L,UBE2V1,EAF2,KRTCAP2,LUC7L,LSG1,NECAP2,ALG3,AGPAT2,CHD3,E2F4,ZNF367,KPNA2,PRPF4,BEND6,CLN3,FAM208A,NGLY1,POT1,MYL12B,CCDC137,RMND5A,HJURP,NEMP2,PHB2,DNAJB2,NKD2,SDC2,KLC1,COX4I1,CDK13,DNAJB1,RAB6A,CNOT11,ARID1B,C1GALT1,MLX,CCP110,ZNF746,ARL6IP1,CTR9,ICE2,NIPSNAP1,ABHD2,DCAF8,ACSL3,LDB1,ARMC8,NPIPA1,RBM38,RMC1,IRF5,NMT2,RPL36,HAUS8,PAXX,MBIP,ORMDL2,COX7A2L,LAMTOR4,ZDHHC7,SIL1,DTD1,UNC13C,BCCIP,SART1,TRAF7,NDUFAF2,TOR1AIP1,ZNF416,LAGE3,ZFYVE21,RRAGC,ZNF121,OIP5,NRF1,WDR44,ABRAXAS2,PPME1,PIN1,RPAP1,AHCYL1,TOP1MT,LMAN1,STRAP,ZNF583,SNX25,ARHGAP17,POLR2G,ZNF780B,PPT1,NUP155,DCLRE1C,MRPS14,RHBDF2,SUGP1,AFDN,RBL1,UBXN2B,STK38,FASTK,AP1S1,SPRYD4,H3F3A,CHID1,SMAD4,RAD51D,SLC30A9,CMAS,AGO2,HMGN3,NCAPG,SCYL2,FZD6,GTPBP3,HERC3,CTSS,ORC3,YTHDC1,ACP2,HMGN5,CSRP1,PRKDC,ABCF2,TUFM,RANGAP1,PNPLA8,HAGH,API5,ZFR,SEC23IP,E2F1,USP20,RBPJ,PDCD6IP,MAX,LUZP1,ADAM10,TSC22D3,CXXC1,AP3M2,CUL1,GYG1,OAT,MYEF2,ANKRD26,MTFR1L,PA2G4,NOL11,FIZ1,ZNF200,AP2B1,MARCH2,SRSF10,SRP72,KLF10,LACTB,SUPT20H,CBFB,RFC2,RAB2B,PRIM1,HHEX,BRD2,LUC7L3,RPS14,MAP4,MRPL27,BTF3,PTPDC1,SLF1,NMD3,CCDC59,PTOV1,COX5B,DNAJC5,SCOC,POLR2K,PRKAA1,TATDN3,PXMP2,PRPF39,PSEN1,ZNF79,PDXDC1,VPS25,NDUFS7,YY1AP1,C12orf10,FAM192A,RPN1,LHX8,ARPC5,ZNRF2,TPST1,DAPK1,CYC1,MRM3,FDFT1,GID8,PIGT,CPQ,WDR1,ZNF574,C1orf35,EXOSC9,ARID1A,FXR1,PTTG1IP,GOSR1,MAP2K2,TWISTNB,AKAP1,HMGN2,XRCC5,PI4K2A,DERL1,CAT,SEC31A,MTHFD2,CEBPG,ARAP1,USP32,FAM83D,CABIN1,SMPD4,GPI,CYTIP,TP53RK,RAB11B,UROD,SLC39A13,POMP,BCL2L1,NUDT19,DECR1,SIAH1,RALB,LPIN2,MRPS27,TTC3,RNASEH2A,CFL1,ANKLE2,VDAC2,EDF1,EML4,ERC1,ANKZF1,RAD51C,ZNF282,DSN1,DDOST,HINT1,DGCR8,RAB24,SAFB,NCLN,BEND3,EYA2,DYNC1LI2,MANBA,B4GALT5,FAM76A,TKT,CBLL1,ARGLU1,POFUT1,HEATR5B,HLA-A,EBP,RFWD3,NDUFA2,FUT8,PTPN11,MRPL54,FEM1B,RPL19,CNN2,NDUFA3,MTX2,MSH6,PDLIM2,RFXANK,GUF1,SPPL2B,RPL32,ZHX1,OAZ2,NDUFS5,WDR91,HIGD2A,GPR89B,RORB,POLA2,ZNF76,MTX3,COPA,KMT2E,UQCR10,HMGXB3,ABCB10,COMMD5,ATP5PF,MAP1LC3B,DST,RAB35,SIVA1,GPATCH1,TCEA1,CARMIL1,DRAM2,DEAF1,SNRNP200,LAP3,NCK1,VHL,SREK1,ARHGDIB,PITPNB,HSPB11,BRWD1,PPM1G,SH3GLB2,CRCP,BAZ1B,CAB39,STK11,CHEK2,CLU,CHPT1,MRPL13,DCAF5,CAPN1,UBE2D3,NSMCE4A,PPP1R12A,GORASP1,ZCCHC8,UBXN1,NACA,RPL15,PCSK7,EPN1,THRAP3,TTF1,QSOX2,PRPF18,NUP205,DTL,MED10,PYURF,ZRANB1,MCPH1,ATP6V0D1,CSNK1G3,ATP5IF1,CREG1,ERLIN1,NUDT4,RPL6,VKORC1,SLTM,EVC2,KLHL15,SIAH2,SLC16A1,DNPH1,SNRNP70,EHD4,C11orf1,APOL2,N4BP2L2,CHMP2A,SNX27,CORO7,PMS2,CLCC1,EXT2,MXD1,USP5,HNRNPA2B1,SAP130,NVL,PPP6C,CYB5R1,UTP4,ZNF770,EBAG9,RNF25,PCGF6,FAM72B,PON2,VPS26C,HNRNPR,STAT6,MAPK1,PDF,TMEM33,NAT14,DNAJC2,TRIP12,SHPRH,SCYL1,VPS45,MYO9B,GFM2,SPPL2A,FASTKD3,FGFR3,MZT2A,KMT5A,PPIG,NABP2,ZDHHC13,H2AFY,NDUFS8,ATG13,FBL,FRMD8,SLC35A1,MICAL3,TGFB1,B3GALT6,ELOVL5,PPP1R9B,HEMK1,TIMMDC1,PSPC1,HELB,MIER1,NADK2,CDK11A,KMT2B,ACAT1,CENPT,PLOD3,RAB14,ADD1,MRPS15,KDM4A,XIAP,DHX8,GLUD1,ANKRD23,PABPC4,CDK5,CALM2,PSMD1,NEK6,NSRP1,RABGAP1L,SRSF4,SPATC1L,PCBP2,KCNAB2,MLST8,PLK3,ZNF672,MRPL43,HSDL1,MCL1,TOPORS,PPFIA3,SMC2,ICMT,SLC50A1,STOML2,ZNF689,LIMK1,PRDX5,ATE1,VIPAS39,MLYCD,ST3GAL2,ATP6V0C,FBXL3,TFDP2,E2F2,AAAS,PFKP,SSRP1,DDX42,MRPL9,MRPS2,TOP2B,TMED3,RAVER2,DDRGK1,GNS,INTS7,MCM5,PHF14,RTCB,ZNF326,UBE2QL1,NAGPA,CYFIP1,TIMM8B,ETV3,TSPYL4,DHX29,MAN1B1,TEX10,RPS10,CBFA2T2,ABCF1,RHOB,SCARB2,OSBPL11,CCDC86,DUSP3,MDH1,SLAIN1,HEXA,SNX14,RNF139,SGF29,ZNF296,FAM208B,TRERF1,UBR2,ACTR3,CHD1L,WDTC1,MYH9,CREBL2,NIPA2,SAFB2,PRKACA,STAM,RAB21,SP100,ZKSCAN1,DDA1,NUP107,ANKRD13C,CEP63,MAVS,RBM15,ATF2,DCTN1,SHOC2,PSRC1,INTS13,WBP2,ATP6V0A1,NUSAP1,DNAJA1,NDUFA7,TAZ,TAF2,SEC61A1,RPLP1,WDR7,RBMS1,FUS,GEN1,COIL,LRP8,ZNF786,RPS2,SESTD1,TRAK1,JMJD6,AKT1S1,KRI1,FBXO3,GATC,NDUFB4,PPP1R8,PRDM4,DCP1A,GEMIN6,GTSE1,SGCB,S100A6,NUDC,PDPK1,MOB4,TNFAIP3,GALC,ZNF512,MRPS10,DDX39A,RPA1,ZNF180,ZNF862,KEAP1,POLE,TATDN2,PITX1,CAPN7,PML,LRPPRC,HMGB2,USF2,ANAPC4,DDX47,MCCC1,CDC42SE2,CDIPT,SEC16A,KCMF1,SSR1,LIN9,PCNA,ZNF639,ETV6,TRMU,PIK3R2,MYBL1,CCAR1,MRPL32,BAZ2A,PBXIP1,TLK1,MRPL12,EZR,LRP5,BRCA1,PRKRA,STX16,OPTN,EPB41,SEPT1,QRSL1,DHFR2,PIEZO1,OSGEPL1,NUDT11,NAA60,GEMIN7,LZTR1,RACGAP1,PPP3CB,B4GALT4,RLF,RAPGEF6,SNRNP25,RB1,VASP,MED8,TIGAR,VMP1,PPIL2,TIMELESS,TMEM8A,ALDH18A1,PREB,ABCC1,TRAPPC9,MEMO1,RTF1,KRAS,UBE4B,NFATC2IP,ARPC1A,ZNF174,PSMC4,GOLGA4,SYNCRIP,PALB2,NIPA1,RNF114,TIGD2,FOXM1,XAB2,MRPL39,SUMO2,DUSP22,COMMD8,RPL11,CSDE1,MDM2,CORO1A,MINPP1,GM2A,DVL2,POC5,PSMA8,COQ10B,CPOX,TIGD5,SLC26A6,PRPF3,TXNL4A,RPSA,SRSF1,DNAJC10,ZNF700,SCAP,TOMM6,TIMM17A,LTA4H,AP2S1,INTS2,CTDP1,MIF4GD,CDT1,ARID5A,SUMF1,GGA2,CSNK1A1,AP3S1,RMI1,TFRC,PTPN2,STARD9,IRF4,GSTK1,NDUFV1,SLC1A4,CWC27,SLC35B4,ABCD1,DDX31,SNX2,ZMYM5,CHCHD6,CDKN2AIPNL,KPNA4,BIRC5,TFE3,SNAP29,CDCA7L,PKD2,ACADM,CHMP7,GCSH,ZNF496,TMEM109,TAP1,NHLRC3,IKBIP,KIFC1,DBNDD1,CYB5RL,PARPBP,CDC25B,MAST2,DNMT1,NOL12,USO1,AKT2,NOL8,ELOA,MRNIP,AURKB,MCFD2,SLC25A5,MAK16,STT3A,TMED10,PSMD8,EIF2D,PTPN7,ITGB1,UQCRH,RRS1,ARRB2,RTN3,SVIP,DDX58,PPIB,MUT,GMFG,HLA-E,NDUFA4,MAN2B1,METTL3,NDUFS4,RNF121,MEX3C,KLF16,DAD1,HDAC7,BDH1,PCYT2,GNAI2,TERF2,MORC3,NOA1,SEPT8,TOMM40,PKM,PATL1,PSMB3,SERTAD2,SERF2,NSF,ZFP92,DCK,ERGIC3,ACLY,LPCAT4,VCPIP1,PPP6R2,PPP6R3,MAP3K5,YY1,CDK2,RNF14,ZC3HAV1,SYS1,ZBTB37,URB2,MAGED1,ADPGK,SLC25A44,AP1B1,SDHA,MOAP1,PHC2,TERF2IP,CRKL,CYHR1,ZNF75D,SHC1,UCHL5,TMBIM1,MRM2,CDKN2AIP,CCT2,HMGN4,LYRM1,CDC23,AP4E1,SHCBP1,PRDM11,VEZF1,PPP2R5A,STAT1,PPA2,TRIM32,R3HCC1L,MRI1,TCF3,BRAP,MYNN,AGPAT3,SDF2L1,SPR,RAB11A,REEP5,FOXO3,MAD2L2,PIP5K1C,MAT2B,RBM17,PTEN,CENPJ,OSTC,CREB1,MAP3K14,NCOA2,PACS2,SMC4,RNASEH2C,NET1,NEK7,PARP4,TBRG4,ANAPC2,RPL27A,YIF1A,SGSH,HGS,TTLL4,ATP5MC3,MFAP1,CCDC69,BRWD3,ESYT2,NPHP4,SKA3,HNRNPAB,DNAJC24,ZNF107,SIRT2,AGFG1,KIF2C,SNRPD3,UBQLN2,FKBP2,USP48,CUTC,EDC3,UBLCP1,ZNF804A,RAP1A,THADA,EIF4A3,AP3S2,DPYSL2,AKR1B1,NDUFB9,RP2,TECR,ARID4A,TIMM50,TDP1,DPM1,FOPNL,SLC25A22,WDR82,STK17B,DHX15,CHAF1A,GEMIN5,TIMM29,COPS6,SASS6,RPS26,PSMC1,TBC1D12,TM9SF4,ZNF768,MED13L,TIA1,MEF2A,EPHX2,PITHD1,RHBDD1,NFATC3,BANF1,BUD31,ZNF335,YBX1,KNTC1,UBE3C,ACAD8,KDELR1,ZNF189,CIC,OXR1,PSMA1,SEPT7,NAP1L1,NSMF,ODF2,NUP62,NAA20,MZT2B,PDSS2,PTDSS1,TMEM106C,ASH1L,IMMT,CHERP,WDYHV1,PLAGL2,IRF3,TWF2,ANKRD28,ANKLE1,SAR1A,APOOL,PDIA6,ACSL5,DMAC2,TOR1AIP2,GFER,RAD54B,DAP3,ZNF317,GADD45B,AKNA,REEP4,CBX4,MIF,KIF3B,GOLPH3L,CASP6,TOR3A,SRGN,DBF4,TIMM21,MFSD10,SAC3D1,CTNNBL1,YIF1B,TTC17,SLC25A1,GINS1,TELO2,CSNK1G2,HMGN1,ADAM17,NASP,ASPM,ATP5MF,SYMPK,SNRPA,TARS,HSPA1B,MAPK3,CNOT9,HLA-B,PLAA,ATAD2,OSBPL8,ZNF330,PREPL |
| 3.472e-112 | -256.64 | organelle part | cellular component | GO:0044422 | 9269 | 1906 | 18223 | 2701 |
ZBTB10,ABCC10,HEXB,TGOLN2,LACTB2,CCNL2,SYNRG,CMTM6,RBM4,FBXO22,RPL23A,NAPG,USF1,RAD23B,MECR,AP1M1,DNM2,CRY2,ECD,RNF26,MOB1A,LRRC59,ZNRD1,MGAT5,RHBDD2,FTSJ3,MRPL57,BAK1,ERCC1,RHOBTB3,NRAS,GABPA,EHMT1,KIF15,HNRNPF,WDHD1,NUTF2,DIDO1,MCM2,COA7,RAB22A,GINS4,KRIT1,AHNAK,SMAD2,MID1IP1,RAD18,RPS27A,MYO18A,OGT,MPV17,COX5A,RNASEL,KLHL42,SMAD1,CHPF2,ANXA11,SMNDC1,SLC25A33,NXT2,CLSPN,SEC61G,GGA1,RHOC,CCZ1,DHX9,RAB23,HAUS4,PDCD7,PSMD9,PARN,CDC73,HAUS2,MYL6B,COPB2,TMEM179B,CD59,SMC3,RNFT1,RBM34,EFTUD2,TNPO3,GEMIN4,MYDGF,MRPL21,CPSF4,MVP,NUP85,PPP6R1,PABPC1,NSUN4,LUC7L2,SRSF11,EIF3L,AGGF1,FOXK1,MAPKAPK3,MTA2,SF3B6,ERO1A,GTPBP4,SSR2,USP10,BCLAF1,MAP7D1,MRPL16,MTX1,ELK1,SFXN5,RDH11,MAGED2,FNTA,KPNA1,TXNDC16,PDLIM1,ETS2,WIPI2,ZNF830,CFAP20,ACSF2,MRPL3,NUP58,ALS2,EXOC3,RHOG,KARS,TRIM41,POC1A,ANK3,STARD7,VTI1A,C5orf30,TPX2,SLC35B2,INO80E,DAZAP2,LCLAT1,GLRX3,STMN1,CPNE3,ZNF420,AHCTF1,MTA1,TBC1D14,GMEB1,NSFL1C,NABP1,CLCN6,SEPT11,MICU2,INTS12,ZC3H3,RPRD1B,CGGBP1,SNX8,CPNE1,ULK3,SEC61B,ERMP1,POLR2L,EID1,FAM118B,GOPC,KAT7,IDH3A,CRNKL1,RPL38,CIRBP,POLR2D,E2F3,PFKFB3,HTATIP2,GORAB,MEF2D,TMEM147,GSTCD,RAB1A,KIF2A,PPP2CA,ALDH3B1,LSM6,CCDC14,NSMCE2,RNF38,SNRPG,PPP5C,PITRM1,TUBB,USP13,MZT1,SRSF6,ZFP91,HABP4,TRMT6,FLOT1,ATG2B,ABHD14B,IP6K2,ATP5F1B,WDR5,IFT27,SLC25A43,NEXMIF,RRP36,SAPCD2,NEIL2,TUT4,GOLM1,RPA2,PSMD2,PDCD10,CLIC4,COQ4,HUWE1,ZNF260,KANSL2,ST8SIA2,GTF2H2,RPL22L1,MED22,SPTAN1,STAU1,TCTEX1D2,DDX24,TACC1,USP42,MRS2,HEBP2,LLPH,PICALM,UTP20,SH3BP5,MAGT1,GPS2,ACOX1,PARG,FAM3C,DBI,AEN,SSNA1,PARP10,YWHAH,WDR13,SNX15,RBM8A,ENSA,NENF,RUFY1,TRIM65,FANCI,PAPOLA,PRNP,KRR1,FANCL,RAB8A,NUP210,GLIS2,TIMM23,INTS1,SLC44A1,POP7,NOC2L,MTPN,TACC3,RYBP,PLK1,RPP25,PTPN18,SEPT9,MIOS,RBX1,APH1A,SNRPB,RAD51AP1,ZBED5,PSMG1,CKAP2L,CDC6,UBE2V1,UTP3,PBRM1,EAF2,KRTCAP2,LUC7L,USP21,LSG1,NECAP2,ALG3,FBXO28,AGPAT2,GRIPAP1,CHD3,E2F4,ZNF367,KPNA2,PRPF4,DVL1,CLN3,FAM208A,POT1,MYL12B,CCDC137,ZNF564,FUBP1,ZCCHC9,NEMP2,HJURP,PHB2,DNAJB2,CENPF,LAMTOR3,SDC2,KLC1,CHCHD2,COX4I1,CDK13,RAB6A,DNAJB1,NCKAP1,ARID1B,SUB1,C1GALT1,MLX,CCP110,KIF13B,MBD2,XPA,ARL6IP1,CTR9,RBM3,ICE2,GLE1,MRPL48,DCAF8,NSDHL,ACSL3,LDB1,CAMSAP1,METTL22,ARMC8,NPIPA1,APPL1,RMC1,HAUS8,RXRB,RPL36,SDHB,PAXX,MBIP,PCM1,GALNT2,ORMDL2,COX7A2L,LAMTOR4,NLRC5,ZDHHC7,SIL1,DTD1,RUVBL2,BTBD10,MYO9A,ECPAS,CCNB2,UNC13C,BCCIP,USP7,SART1,RPLP2,SUCLG1,ARID2,NDUFAF2,TOR1AIP1,SLC2A1,LAGE3,ZFYVE21,RRAGC,ATP6V1B2,PCBP1,LYN,BCAP31,OIP5,MRPL50,NRF1,PSMA6,ZNF473,KMT5C,BRPF3,WDR44,ABRAXAS2,PIN1,PPME1,TARDBP,BCAP29,TOP1MT,AHCYL1,LMAN1,STRAP,CTDSP2,SPIDR,PRPF19,SNX25,PPIF,KDM3B,CLCN3,BIRC3,POLR2G,PPT1,RAB7A,PPIE,NUP155,DCLRE1C,CHMP2B,VDAC1,MRPS14,RHBDF2,TMEM201,AFDN,SUGP1,IDE,DHX16,RBL1,FASTK,UHRF2,AP1S1,CHMP4B,XRCC3,H3F3A,CHID1,SMAD4,RAD51D,NIFK,CMAS,C19orf53,MCM10,MTERF1,KLHL21,PDAP1,AGO2,CDCA8,TMX3,GTF3A,HMGN3,ARF1,NCAPG,PAGR1,SCYL2,TUBGCP2,DNAJB9,FZD6,HOMER1,CTSS,POLR1B,ORC3,RNF5,RBM15B,YTHDC1,PPAN,ACP2,RHOA,RPRD1A,HMGN5,BTAF1,PRKDC,ABCF2,TUFM,TOP3A,RANGAP1,PNPLA8,PCGF1,HAGH,API5,DDX23,RAB18,PDCD6,ATP6V1D,SEC23IP,NEK1,L3MBTL3,FAM110A,NEIL3,BBX,E2F1,USP20,IMPDH1,RBPJ,TAF12,NR2F2,PGAM1,HIPK3,IFI16,NUP188,MAX,H2AFZ,PNISR,PDCD6IP,TMEM203,PRKCSH,ADAM10,CXXC1,AP3M2,CUL1,USP39,GYG1,OAT,UBE2I,PARK7,SLC25A37,GLMP,ANKRD26,PA2G4,NOL11,RAB4A,TRA2B,SUCLG2,AP2B1,TAF5L,CISD2,MARCH2,SMARCE1,SRSF10,CDC5L,NSUN2,SUPT20H,USP22,CBFB,RFC2,RAB2B,CLNS1A,EIF3A,PRIM1,ZMYM3,DOT1L,IWS1,MKNK1,WAS,KIF18B,BRD2,RPS14,TPP2,LUC7L3,MAP4,MRPL27,PTPDC1,SLF1,CCDC59,ZMAT3,NMD3,B4GALT2,PRPF38B,RECQL,C9orf78,COX5B,DNAJC5,EWSR1,SCOC,POLR2K,PRKAA1,RRM1,ACAP1,B4GALT1,PXMP2,CYCS,PRPF39,SUPT7L,PSEN1,TMEM165,VPS25,NDUFS7,NPLOC4,YY1AP1,SPAG5,WDR48,RTKN,C12orf10,TMEM250,RPN1,CEP104,EXOSC7,ARPC5,ZNRF2,LRRC8D,MSH2,PIGG,TPST1,FBXL7,OSTF1,CYC1,MRPL40,TNRC18,MRM3,APOL1,FDFT1,GID8,EIF5A,GCC2,PIGT,PRIM2,COQ8A,ELL2,WDR1,RDH10,USF3,MFNG,RPS24,C1orf35,GORASP2,EXOSC9,ARID1A,CAPZA2,ADRB2,FXR1,PTTG1IP,GOSR1,MAP2K2,CCT8,TWISTNB,PHF6,AKAP1,PI4K2A,HMGN2,XRCC5,DERL1,SEC31A,CAT,MTHFD2,GOLGA2,EPOP,RBMX,MED15,PIAS2,FAM83D,APPL2,ARAP1,CEBPG,CABIN1,SAMD8,SMPD4,GPI,CDKN2A,CYTIP,NDC1,TP53RK,ATXN3,RAB11B,RAF1,UROD,SLC39A13,POMP,BCL2L1,C2orf49,CD320,NUDT19,DECR1,CCNA2,MTMR4,LPIN2,MRPS27,BRI3,TAP2,TTC3,TP53BP2,RNASEH2A,AQR,ILKAP,CDK12,CFL1,SAP30,ANKLE2,BRD4,NARF,VDAC2,ELP4,EDF1,PKMYT1,ERC1,SERP1,EML4,TRIM28,SUPT16H,ANKZF1,RAD51C,CHMP4A,HINT1,DDOST,DSN1,RAB24,DGCR8,CERS6,SAFB,ATF6,NCLN,BEND3,XRCC4,EYA2,DYNC1LI2,PRPF4B,NDUFS1,B4GALT5,MECP2,MANBA,TKT,FAM76A,CBLL1,ARGLU1,SPDL1,HLA-A,SLC25A36,JAKMIP1,EBP,RFWD3,CCNK,DNAJC8,NDUFA2,FUT8,AXIN2,PTPN11,MRPL54,FEM1B,RPL19,CARF,CNN2,CITED2,NDUFA3,MTX2,MSH6,KAT2A,TMEM126B,RFXANK,BMS1,KCNQ1,ARSK,MACF1,KIF11,KLF6,GUF1,SPPL2B,SH3GLB1,MYO1F,CBX3,RPL32,ZHX1,DUSP11,DDX5,NDUFS5,WDR62,WDR91,TAF6,ESPL1,PURA,DDB1,DEF6,HIGD2A,GPR89B,IPO4,POLA2,RORB,CCNC,PIGM,LYRM4,MTX3,COPA,KMT2E,UQCR10,ABCB10,COMMD5,BRIX1,ATP5PF,MAP1LC3B,MRPL19,SF3B2,PCYOX1L,DST,CDC42,SYNM,GOT2,SIVA1,RAB35,JAZF1,HADHB,RPF2,GPATCH1,TCEA1,SLC35C2,CARMIL1,DRAM2,CARM1,SRPK2,WDR41,LARS,DEAF1,SNRNP200,NCK1,LAP3,VHL,TMEM216,RIOX2,SREK1,SUMF2,PITPNB,KMT2C,MPC1,ASF1B,RPL37,MAN2A2,HSPB11,EIF4ENIF1,BRWD1,NIP7,U2SURP,PPM1G,SH3GLB2,MIA2,CRCP,CAB39,BAZ1B,STK11,CHEK2,CLU,VPS4A,CHPT1,MRPL13,ATP6V0E1,DCAF5,CAPN1,UBE2D3,NSMCE4A,PPP1R12A,GORASP1,ZCCHC8,UBXN1,PCSK7,RPL15,THRAP3,PM20D2,RGS2,TTF1,QSOX2,PRPF18,NUP205,LYAR,DTL,MED10,PYURF,EI24,ZRANB1,MCPH1,ATP6V0D1,ATP5IF1,POLR2I,CREG1,ERLIN1,SUGP2,RPL6,GBA,EIF2A,SYVN1,VKORC1,SLTM,DAPK3,EVC2,MASTL,UAP1,SIAH2,SLC16A1,YWHAZ,CTSA,SNRNP70,EHD4,C11orf1,TMEM14A,APOL2,TSEN15,TCF12,CHMP2A,SNX27,PRKAB1,CORO7,MDH2,PMS2,SMARCA4,ORC1,EXT2,MXD1,SAP130,HNRNPA2B1,RRN3,UBXN2A,NVL,CD3EAP,KIF14,EXOSC1,PPP6C,CS,CYB5R1,CLTB,UTP4,DNAL4,EBAG9,CSTF1,CHP1,POU2AF1,UBQLN4,NXT1,SMU1,PCGF6,ATXN1,LSM8,OGDH,BICD2,EDEM2,TOLLIP,FANCE,MBD3,PDHX,RPS9,ALKBH6,SURF4,HNRNPR,STAT6,ARNTL,ANP32E,FKBP5,MAPK1,ABCA1,TMEM33,CWC25,DNAJC2,TRIP12,SHPRH,RAE1,SCYL1,DCTN2,NUP54,VPS45,PAWR,MYO9B,PIP4K2A,GFM2,FERMT3,SPPL2A,KIF5B,MZT2A,KLHL20,SEC24C,KMT5A,PPIG,RRBP1,NABP2,ZDHHC13,H2AFY,ARHGEF2,ANP32A,ATG13,NDUFS8,FBL,STAT3,SLC35A1,MYO5A,MICAL3,TGFB1,B3GALT6,ELOVL5,COA3,PPP1R9B,DCAF6,FAM49B,TIMMDC1,PSPC1,HELB,MIER1,ATP2C1,RFFL,NADK2,COG1,RCOR1,PRMT2,LEMD2,CTSL,UPF1,KMT2B,ACAT1,CENPT,ZMIZ1,PLOD3,TERF1,HRAS,SLF2,RAB14,FGFR1OP,TMED7,ADD1,MRPS15,KDM4A,PIGQ,XIAP,AGPAT1,DHX8,GLUD1,CNTROB,PPP1R16B,ANKRD23,MIS12,CALM2,CDK5,PSMD1,NEK6,NSRP1,SRSF4,PDS5B,NUP153,SPATC1L,SENP1,PCBP2,KCNAB2,MLST8,PLK3,PGAP2,ZNF672,TMEM115,AATF,MRPL43,TOPORS,MCL1,SMC2,ICMT,SLC50A1,PLEKHF2,STOML2,BRMS1,PWWP2B,WDR11,LIMK1,PRDX5,MLYCD,ATP6V0C,ST3GAL2,FBXL3,TFDP2,E2F2,LONP2,AAAS,SSRP1,DDX42,NDUFV2,MRPL9,PHF23,MRPS2,TOP2B,TMED3,EZH1,LMNA,MCTS1,DDRGK1,GNS,DDX56,INTS7,MCM5,RTCB,ZNF326,CARS2,NAGPA,TIMM8B,CYFIP1,ETV3,PRRC2A,RB1CC1,ZMYND11,PGS1,MAN1B1,TEX10,RPS10,MYBL2,SRSF5,MPG,ABCF1,MATR3,CYB5A,RHOB,SCARB2,OSBPL11,CCDC86,POLR2J,DUSP3,SETD3,NDE1,HEXA,SNX14,RNF139,SGF29,ZNF207,ANKRD27,FAM208B,ABCA3,SARNP,TRERF1,IVNS1ABP,UBR2,ACTR3,CHD1L,WDTC1,TMEM97,RMI2,MON1B,MYH9,RXYLT1,NUF2,NIT2,PRKACA,SAFB2,APP,STAM,KTN1,RAB21,CLUAP1,PRKD3,ATP2A2,SP100,UTP18,GRSF1,DUT,DDA1,NUP107,ANKRD13C,ANAPC7,RNF19A,CEP63,MAVS,FAM76B,RBM15,CLN6,ATF2,GCC1,TMEM9,RNF169,DCTN1,ATP6V1G1,ENPP4,SHOC2,PSRC1,INTS13,RNPS1,WBP2,ATP6V0A1,CDCA2,NUSAP1,NDUFA7,DNAJA1,TAZ,DDX17,CHCHD3,TAF2,PEX5,CDC16,SEC61A1,HIPK2,RPLP1,MBOAT1,TICAM1,FUS,PDXK,ZBTB11,GEN1,COIL,LRP8,RPS2,ANXA6,TMBIM4,GMCL1,JMJD6,AKT1S1,ETS1,WRB,PNO1,KRI1,CAPN2,FBXO3,ADD3,SUV39H2,NDUFB4,PPP1R8,PRDM4,GEMIN6,GTSE1,TPCN1,S100A6,TMX1,LYPLA2,HNRNPM,MFSD12,NUDC,MOB4,PDPK1,PPP3CA,POLK,GALC,JTB,MRPS10,DDX39A,RPA1,KIF18A,KEAP1,POLE,WNT5B,TATDN2,PITX1,MAPK6,PML,LRPPRC,SLC25A19,HMGB2,PSAP,USF2,FAF1,ANAPC4,SNAPIN,COX15,DDX47,AGRN,THOC1,MCCC1,CSNK2A1,EBNA1BP2,CDIPT,SEC16A,GIT2,KCMF1,SSR1,LIN9,DLG5,PCNA,ZNF639,TRMU,XRCC2,ETV6,ZFYVE27,MCMBP,MRPL32,CCAR1,PTPRK,METTL1,SP3,EXOSC6,PBXIP1,BAZ2A,CYSTM1,MRPL12,EZR,BRCA1,ESYT1,PRKRA,ANLN,STX16,RAB5B,RHEB,OPTN,DPYSL3,SEPT1,TIMM13,CDCA4,TONSL,NRM,NAGLU,ACTB,PIEZO1,DHFR2,ZNF45,SINHCAF,NAA60,C2CD5,GEMIN7,TMUB1,CTCF,ASAH1,RACGAP1,PPP3CB,B4GALT4,ASXL2,RAPGEF6,SNRNP25,RB1,NUS1,MED8,TIGAR,VMP1,PPIL2,TIMELESS,SLC27A4,AFF1,MDFIC,MAML1,TMEM8A,ALDH18A1,ABCC1,PREB,CYTH1,TRAPPC9,NQO2,UTP15,RTF1,ARPC1A,ZDHHC3,ZNF174,PSMC4,MOSPD3,GOLGA4,CDC27,PALB2,SYNCRIP,SNAP23,TBPL1,PRMT7,ATP5F1A,NDUFA5,CYLD,FOXM1,XAB2,DYNLL1,MRPL39,SUMO2,COPE,HCFC1R1,COMMD8,RPAIN,RAD23A,RPL11,SEC11A,ZBTB21,ATP6V0B,PDK2,MDM2,TNFAIP8,MRPL34,CORO1A,MINPP1,SAP30L,DVL2,POC5,GM2A,RPL29,TIMP2,RPL35,COQ10B,CPOX,TUBGCP5,SLC26A6,DNAJC9,MTMR6,NFATC2,PRPF3,KDM1B,TXNL4A,RPSA,USP36,SRSF1,DNAJC10,MRPL2,CLK3,SCAP,TOMM6,TIMM17A,PSMD3,MAFK,CEP55,NDUFA11,ZNF436,NCOA1,LTA4H,SLC25A39,AP2S1,ZC3HC1,ZNF146,INTS2,CTDP1,MIF4GD,CDC40,GOLIM4,CDT1,ARID5A,SMC6,ARFIP2,SUMF1,NKRF,GGA2,AP3S1,CSNK1A1,RMI1,TFRC,WRNIP1,PTPN2,GSTK1,STARD9,IRF4,NDUFV1,SLC1A4,CWC27,SLC35B4,ABCD1,SS18L1,DDX31,CENPM,PTGES3,CAMK2G,MLEC,SNX2,ZMYM5,PPWD1,FAM50B,RHOT2,CHCHD6,NEU1,KPNA4,CDKN2AIPNL,GOLGA7,BIRC5,SNAP29,TFE3,CDCA7L,GLG1,PGRMC1,PKD2,SPCS3,ACADM,CHMP7,UBE2C,GCSH,ZNF496,NDUFB6,ZDHHC8,TAP1,TMEM109,NHLRC3,CCNB1,IKBIP,RIC1,POLR3K,UTP25,KIFC1,ASAP2,SNUPN,DBNDD1,CYB5RL,PARPBP,CDC25B,TFG,SPTSSA,DNMT1,SEH1L,NOL12,USO1,ATG9A,AKT2,ARHGAP45,NOL8,MKI67,ELOA,DDX20,MRNIP,GALNT7,SLC17A5,AURKB,MCFD2,CCNF,FOXRED1,SLC25A5,MAK16,STT3A,TMED10,PSMD8,WDR4,EIF2D,PTPN7,SARAF,DHTKD1,UQCRH,RRS1,TRAF5,RTN3,HDAC2,SVIP,PPIB,HSPH1,LIME1,MAPRE1,GMFG,MUT,CHTF18,HLA-E,KIF23,NDUFA4,SLC35B1,NOTCH2,PMF1,MAN2B1,COPG2,METTL3,JMY,NDUFS4,FKBP1A,NDUFAF6,RNF121,SNX18,DAD1,HDAC7,BDH1,SLC25A51,ATP6V0A2,PCYT2,PIKFYVE,GNAI2,LPCAT1,EEF1D,TMED2,TERF2,MORC3,FTL,PHF10,DDX28,SIGMAR1,NOA1,SEPT8,PLEC,TOMM40,PKM,KDM3A,SF3A2,PATL1,PSMB3,FAS,SERTAD2,NSF,QARS,ERGIC3,ACLY,DCAF11,PPP3R1,LPCAT4,VCPIP1,TCOF1,YY1,MAP3K5,PPP6R3,CDK2,NRBP1,DNMT3A,SYS1,TRIP10,URB2,SF3B1,SUZ12,RPS6KA1,MAGED1,RAC1,GPR89A,OLA1,ADPGK,AP1B1,SLC25A44,SNN,SDHA,GNB2,PHC2,FLAD1,CRKL,MOAP1,TERF2IP,CYHR1,APLP2,SHC1,KDM2A,UCHL5,CDKN1B,TNPO2,TALDO1,TMBIM1,MRM2,GPX4,CCT2,CDKN2AIP,ATP13A1,MAPRE2,RFC3,HMGN4,ERF,LYRM1,CUL3,SLBP,CDC23,AP4E1,H2AFV,SHCBP1,GAR1,PSMB9,POLG2,CENPU,NSA2,VEZF1,PPP2R5A,MRPL55,FAAP100,GOLGA8A,TBL3,PPA2,SEL1L,STAT1,H2AFX,TRIM32,B4GALT3,PDCD11,CSNK1D,ATMIN,POLQ,NCOR2,PKP4,R3HCC1L,TWNK,BABAM1,MRI1,TCF3,BRAP,SLC25A12,AGPAT3,SDF2L1,BLM,SPR,FOXO3,REEP5,RAB11A,MAD2L2,GTF2F1,PIP5K1C,RBM17,PTEN,RPL17,CRAT,CENPJ,PRC1,UPF2,COPS7B,CREB1,MAP3K14,OSTC,CNPY3,UBE2M,IFT46,NCOA2,SMC4,ZFP64,DENND4C,NEK7,DENND1B,WDR18,RPL8,PARP4,ILF3,TBRG4,ANAPC2,RHOT1,RPL27A,MARK2,POLR2A,YIF1A,PLD3,NUCB1,SGSH,HGS,ATP5MC3,PRDX3,TTLL4,CCZ1B,HNRNPH3,TFDP1,STX18,NAXE,KHSRP,CCDC69,ASNA1,VPS29,BYSL,DDX52,S100PBP,ESYT2,ADA2,IER2,SKA3,NPHP4,NOP2,HNRNPAB,UBN1,NF1,ALKBH5,MOGS,UBE2Z,TAF6L,AGFG1,SIRT2,KIF2C,FKBP2,USP48,SNRPD3,MAPK14,BECN1,CUTC,SNAPC4,RNF103,BCAT2,UBLCP1,MBD4,ZNF804A,RAP1A,EIF4A3,THADA,AP3S2,METTL14,DPYSL2,IMPAD1,RCSD1,PHTF1,SRI,KHDC4,AKR1B1,KIF22,NDUFB9,RP2,NFU1,TECR,OGG1,ARID4A,TRIM14,ELOF1,TIMM50,COPS8,FYTTD1,TRIM8,DPM1,FOPNL,WDR82,SLC25A22,SOX4,DHX15,CHAF1A,UBTF,GEMIN5,PAF1,SPATA2,TIMM29,PQBP1,IARS2,ATXN2L,GALNT10,ROCK1,COPS6,SASS6,RPS26,PSMC1,STARD3NL,CEP170B,RPS15,PIGN,AGTRAP,ZNF768,CIB1,CDIP1,TIA1,MED13L,MEF2A,XPO7,SRRT,RHBDD1,NFATC3,BANF1,ZNF335,BUD31,CAPZA1,YBX1,BCL2,KIFAP3,KNTC1,ACAD8,KDELR1,HP1BP3,VOPP1,CIC,OXR1,PSMA1,SEPT7,ISG15,CAND1,TSC1,RBM25,NSMF,CDCA5,ODF2,NUP62,RBBP4,HNRNPDL,NIPSNAP2,PDSS2,MZT2B,PTDSS1,SMARCD1,TMEM106C,MBD1,TOMM20,ASH1L,IMMT,GNPNAT1,MPHOSPH8,FAM92A,CHERP,HNRNPUL2,NSD3,IRF3,TWF2,CHD1,MEAF6,MIEF1,ANKRD28,ANKLE1,BABAM2,SAR1A,AKAP8,PARL,RPN2,APOOL,CHTOP,PDIA6,TMEM14C,HTRA2,MOSPD1,RLIM,ACSL5,FAM172A,ZNF500,DMAC2,PSMB7,NLN,WIPF1,TOR1AIP2,ERBIN,BUD13,NDUFB1,PEF1,GFER,DAP3,TAB2,CHCHD1,TULP3,WDR59,CANT1,SCARB1,GAS2,USP11,AKNA,SMURF1,REEP4,CBX4,MIF,KIF3B,CDS2,GOLPH3L,MRPL42,CASP6,EYA1,TOR3A,CDK2AP2,SRGN,MRPS26,DBF4,LETMD1,TIMM21,MFSD10,MAN1A1,SAC3D1,FBXO5,CTNNBL1,BRD7,YIF1B,MRPL11,SLC25A1,GINS1,GTF3C6,TELO2,HMGN1,NASP,ASPM,PRKAR1B,POLR3GL,WDR81,ATP5MF,MEN1,SYMPK,SNRPA,MFN2,HSPA1B,MAPK3,HLA-B,ATAD2,ZNF330,OSBPL8,COX8A,ZRANB2,SRSF3,MBD6,IDH3B,TATDN1,ATP6V1C1 |
| 3.524e-100 | -229.00 | membrane-bounded organelle | cellular component | GO:0043227 | 12248 | 2269 | 18223 | 2701 |
HECA,ZBTB10,ABCC10,HEXB,TGOLN2,CCNL2,SYNRG,FBXO22,RAD23B,ATP13A3,DNM2,ZNRD1,FTSJ3,ERCC1,NRAS,EHMT1,HNRNPF,WDHD1,MIER2,DIDO1,MCM2,RAB22A,SMAD2,MID1IP1,RPS27A,MYO18A,OGT,MPV17,COX5A,SMAD1,ZNF75A,ANXA11,SLC25A33,SEC61G,GGA1,MUM1,CCZ1,CUTA,RAB23,KCTD17,APH1B,PARN,CDC73,MYL6B,TMEM179B,SMC3,TNPO3,GEMIN4,MVP,NUP85,PPP6R1,PABPC1,NSUN4,PPA1,IFRD1,AGGF1,FOXK1,RBM42,GTPBP4,MRPL16,ELK1,RDH11,MAGED2,KPNA1,ETS2,WIPI2,ACSF2,FAM72D,EXOC3,RHOG,STARD7,VTI1A,SLC35B2,INO80E,RCOR3,LCLAT1,CPNE3,RBM23,ZNF420,AHCTF1,TBC1D14,GMEB1,NSFL1C,ZNF226,GPD1L,ZC3H3,PDCL3,SNX8,ERMP1,EID1,IDH3A,POLR2D,HTATIP2,MEF2D,TMEM147,GSTCD,VPS26B,CORO1C,NSMCE2,CAMKMT,PPP5C,PITRM1,TUBB,COMMD10,ZNF445,SRSF6,HABP4,CCM2,FLOT1,ATG2B,ABHD14B,ATP5F1B,HDGFL2,NEXMIF,TUT4,PPP1R3B,GOLM1,ZBTB45,HUWE1,ZNF260,NAA50,ANXA5,KANSL2,NAP1L4,ZNF710,ST8SIA2,MED22,SPTAN1,STAU1,DDX24,TACC1,USP42,MRS2,LDHA,HEBP2,LLPH,RAB3IP,PICALM,SH3BP5,ACOX1,PARG,FAM3C,AEN,PARP10,YWHAH,THAP5,FAM129A,TRIM11,YTHDC2,SNX15,RBM8A,ENSA,NENF,SND1,RUFY1,TRIM65,PRNP,KRR1,RAB8A,NUP210,NOC2L,EIF5,RYBP,PTPN18,MIOS,SNRPB,MBLAC2,CDC6,UTP3,PBRM1,USP21,TRAM2,GRIPAP1,ARRDC1,ADAM9,DVL1,NUMB,ZNF564,FUBP1,PARP12,ZCCHC9,CENPF,LAMTOR3,CHCHD2,NCKAP1,RSAD1,SUB1,RINL,SSBP3,MBD2,XPA,AHCY,RBM3,GLE1,MRPL48,HDHD2,NSDHL,ZNF761,METTL22,APPL1,RXRB,SDHB,PCM1,GALNT2,TMEM168,NLRC5,RUVBL2,BTBD10,ECPAS,CCNB2,USP7,GLT8D1,RPLP2,SUCLG1,ARID2,TMX4,SLC2A1,ATP6V1B2,PCBP1,LYN,BCAP31,MRPL50,PSMA6,ZNF473,ZNF302,KMT5C,BRPF3,TARDBP,BCAP29,CTDSP2,SPIDR,PRPF19,PPIF,KDM3B,MND1,CLCN3,BIRC3,RAB7A,PPIE,CHMP2B,VDAC1,EIF3H,TMEM201,GLOD4,IDE,DHX16,UHRF2,CHMP4B,XRCC3,BCL2L12,NIFK,C19orf53,MCM10,MTERF1,PDAP1,TMX3,CDCA8,GTF3A,ARF1,SLC12A9,CDK11B,PAGR1,TUBGCP2,DNAJB9,POLR1B,RNF5,RBM15B,PPAN,RHOA,RPRD1A,BTAF1,TOP3A,ARHGEF12,PCGF1,DDX23,RAB18,TRIM26,PDCD6,ATP6V1D,NEK1,L3MBTL3,NEIL3,CTBS,BBX,IMPDH1,TAF12,NR2F2,PGAM1,ARHGAP23,HIPK3,IFI16,TXN,NUP188,H2AFZ,PNISR,TMEM203,PRKCSH,USP39,UBE2I,PARK7,SLC25A37,GLMP,RAB4A,TRA2B,SUCLG2,TAF5L,CISD2,SMARCE1,ZNF800,CDC5L,ZNF524,SGCE,NSUN2,USP22,CLNS1A,EIF3A,ZMYM3,DOT1L,IWS1,MKNK1,WAS,KIF18B,TPP2,C1orf109,ZMAT3,FAM72C,B4GALT2,PRPF38B,RECQL,C9orf78,EWSR1,GADD45G,RRM1,ACAP1,B4GALT1,CYCS,SUPT7L,ZNF518A,TMEM165,CNOT3,NPLOC4,WDR48,TMEM250,EXOSC7,LRRC8D,MSH2,PIGG,OSTF1,MRPL40,TNRC18,SYTL3,APOL1,EIF5A,GCC2,PRIM2,COQ8A,ELL2,RDH10,MFNG,USF3,RPS24,GORASP2,CAPZA2,ADRB2,CCT8,PHF6,PFDN5,GOLGA2,EPOP,RBMX,MED15,PIAS2,APPL2,SAMD8,CDKN2A,NUDT3,ZNF511,NDC1,ATXN3,RAF1,C2orf49,CD320,EPM2A,CCNA2,MTMR4,BRI3,TAP2,TP53BP2,AQR,ILKAP,CDK12,SAP30,BRD4,DRAP1,NARF,ELP4,ABHD11,PKMYT1,SERP1,TRIM28,SUPT16H,EIF3K,CHMP4A,CERS6,ATF6,XRCC4,PRPF4B,NDUFS1,DEPDC1,MECP2,SECISBP2,SPDL1,HMG20A,WWP2,SLC25A36,CCNK,DNAJC8,ELP5,AXIN2,CARF,CITED2,ANKRD37,KAT2A,TMEM126B,PACS1,BMS1,KCNQ1,ARSK,MACF1,KIF11,COMMD4,KLF6,SMAP2,FADD,SH3GLB1,CBX3,TMEM127,PPP1R11,DUSP11,DDX5,WDR62,TAF6,ESPL1,PURA,DDB1,DEF6,FAM83G,IPO4,UBL3,CCNC,PIGM,LYRM4,UBE2Q1,PTP4A3,BRIX1,MRPL19,ZNF696,SF3B2,PCYOX1L,CDC42,GOT2,JAZF1,HADHB,RPF2,SLC35C2,CARM1,SRPK2,WDR41,LARS,LRBA,RIOX2,SUMF2,KMT2C,OGFR,MPC1,ASF1B,MAN2A2,EIF4ENIF1,NIP7,U2SURP,MIA2,ZNF268,VPS4A,ATP6V0E1,PM20D2,XPNPEP3,RGS2,LYAR,EI24,POLR2I,SUGP2,GBA,SYVN1,DAPK3,MASTL,UAP1,NFIL3,YWHAZ,CTSA,TMEM14A,TOB1,TSEN15,ADNP2,TCF12,PRKAB1,MDH2,SMARCA4,ORC1,RRN3,UBXN2A,IARS,CD3EAP,KIF14,EXOSC1,CS,CLTB,CSTF1,CHP1,POU2AF1,UBQLN4,NXT1,SMU1,ATXN1,LSM8,GLO1,OGDH,BICD2,EDEM2,TOLLIP,FANCE,MBD3,PDHX,RPS9,ALKBH6,SURF4,ARNTL,ANP32E,FKBP5,ABCA1,CWC25,ZNF316,RAE1,DCTN2,NUP54,CHIC2,PAWR,MXD4,DCUN1D4,PIP4K2A,XPR1,FERMT3,KIF5B,KLHL20,SEC24C,RRBP1,DUS2,ARHGEF2,ANP32A,STAT3,MYO5A,TXNL1,COA3,PHF20L1,DCAF6,FAM49B,ATP2C1,RFFL,COG1,RCOR1,PRMT2,TFEB,LEMD2,CTSL,UPF1,ZC3H7B,ZMIZ1,TERF1,HRAS,SLF2,CCDC93,FGFR1OP,TMED7,MAP3K7CL,PIGQ,AGPAT1,PPP1R16B,EDRF1,MIS12,CIPC,PDS5B,NUP153,SENP1,PGAP2,TMEM115,AATF,PLEKHF2,BRMS1,PWWP2B,TRIM47,WDR11,AXIN1,LONP2,NDUFV2,PHF23,EZH1,ITGB5,LMNA,DDX56,EIF2S2,FOXN2,CARS2,PRRC2A,RB1CC1,ZMYND11,PGS1,MYBL2,SRSF5,MPG,MATR3,CYB5A,NCDN,POLR2J,SETD3,TEX30,CNOT6,EGLN1,ZNF207,ANKRD27,ABCA3,SARNP,IVNS1ABP,MON1B,RMI2,TMEM97,NIT2,RXYLT1,NUF2,ZNF267,TCF19,KTN1,APP,PRKD3,CLUAP1,ATP2A2,UTP18,GRSF1,DUT,ANAPC7,FAM76B,CLN6,TMEM9,GCC1,RNF169,ATP6V1G1,ENPP4,RNPS1,CDCA2,FKBP3,DDX17,CHCHD3,PEX5,CDC16,HIPK2,MBOAT1,TICAM1,PDXK,ZBTB11,ANXA6,TMBIM4,GMCL1,UBE4A,ETS1,WRB,ZNF92,PNO1,CAPN2,ADD3,SUV39H2,TPCN1,TMX1,LYPLA2,HNRNPM,MFSD12,LDHB,PPP3CA,POLK,JTB,PDE3B,KIF18A,WNT5B,MAPK6,LY75,SLC25A19,PSAP,WDR76,FAF1,SNAPIN,COX15,AGRN,THOC1,GNPDA1,GPBP1L1,PPP1R15B,CSNK2A1,EBNA1BP2,GIT2,BIRC2,ATPAF1,XRCC2,ZFYVE27,MCMBP,PTPRK,CDC37,METTL1,SP3,EXOSC6,HARS,CYSTM1,ESYT1,ANLN,RAB5B,RHEB,DPYSL3,TBC1D17,TIMM13,CDCA4,TONSL,NRM,NAGLU,ACTB,ZNF45,SINHCAF,C2CD5,TMUB1,CTCF,ASAH1,CRLF3,ASXL2,NUS1,CMTR2,SLC27A4,AFF1,MDFIC,MAML1,CYTH1,NQO2,UTP15,ZDHHC3,SPATA33,MOSPD3,CDC27,SNAP23,TBPL1,PRMT7,ATP5F1A,NDUFA5,UGP2,DYNLL1,COPE,HCFC1R1,ZADH2,RPAIN,RAD23A,SEC11A,PDK2,ATP6V0B,ZBTB21,STRBP,TNFAIP8,MRPL34,PDCD2,SAP30L,TIMP2,RPL35,BTG2,DNAJC9,MTMR6,NFATC2,KDM1B,USP36,MRPL2,ATP1A1,CLK3,PSMD3,MAFK,NDUFA11,DNAJC17,ZNF436,NCOA1,SLC25A39,ZC3HC1,ZNF146,CDC40,GOLIM4,SMAP1,SMC6,ARFIP2,NKRF,WRNIP1,SS18L1,CENPM,PTGES3,CAMK2G,MLEC,ZNF202,PPWD1,FAM50B,RHOT2,NEU1,GOLGA7,GLG1,PGRMC1,SPCS3,RPS6KC1,UBE2C,NDUFB6,ZDHHC8,PLXNA1,CCNB1,COMMD6,RIC1,POLR3K,C14orf119,UTP25,ASAP2,SNUPN,SPTSSA,TFG,SEH1L,ATG9A,ARHGAP45,PBK,MKI67,DDX20,AMDHD2,GALNT7,SLC17A5,CCNF,FOXRED1,RBM47,PTER,WDR4,SARAF,DHTKD1,HDAC2,PWWP2A,HSPH1,LIME1,MAPRE1,CHTF18,ADO,KIF23,SLC35B1,NOTCH2,PMF1,COPG2,JMY,FKBP1A,NDUFAF6,SLC31A1,SNX18,ATIC,SLC25A51,ATP6V0A2,PIKFYVE,LPCAT1,EEF1D,TMED2,PHF10,FTL,DDX28,ZNF84,SIGMAR1,PIP4K2C,PLEC,CYFIP2,KDM3A,SF3A2,FAS,ZNF777,QARS,CSNK1G1,DCAF11,PPP3R1,TCOF1,CABLES1,NRBP1,DNMT3A,TRIP10,SF3B1,SUZ12,CAST,RPS6KA1,RAC1,GPR89A,OLA1,SNN,SDE2,GNB2,FLAD1,APLP2,KDM2A,TNPO2,CDKN1B,TALDO1,GPX4,ATP13A1,RFC3,ERF,TAOK1,CUL3,SLBP,H2AFV,GAR1,PSMB9,POLG2,CENPU,DHX57,SOCS7,NSA2,HSPA4,MRPL55,JAK1,FAAP100,GOLGA8A,TBL3,SEL1L,H2AFX,B4GALT3,PDCD11,CSNK1D,ATMIN,POLQ,POU3F2,NCOR2,ANKRD13D,SCAMP3,TWNK,BABAM1,SLC25A12,BLM,GTF2F1,RPL17,CRAT,AHSA1,PRC1,UPF2,COPS7B,SLC38A10,CNOT6L,CNPY3,UBE2M,TSHZ1,ZFP64,STRIP1,DENND4C,DENND1B,WDR18,ILF3,RHOT1,MARK2,TSR2,ECH1,POLR2A,PRDX1,PLD3,NUCB1,PRDX3,PFDN4,CCZ1B,HNRNPH3,TFDP1,STX18,NAXE,KHSRP,ASNA1,CPEB2,VPS29,BYSL,DDX52,S100PBP,ADA2,MIB2,IER2,PTMS,NOP2,UBN1,NF1,ALKBH5,MOGS,UBE2Z,TAF6L,BECN1,MAPK14,SNAPC4,RNF103,BCAT2,MBD4,CYREN,CMSS1,METTL14,IMPAD1,ZNHIT6,PHTF1,SRI,KHDC4,KIF22,ZBTB22,NFU1,OGG1,TRIM14,ELOF1,COPS8,FYTTD1,TRIM8,SOX4,CXXC4,UBTF,PAF1,UEVLD,SPATA2,PQBP1,IARS2,ATXN2L,ROCK1,GALNT10,STARD3NL,RPS15,PIGN,AGTRAP,CIB1,CDIP1,XPO7,SRRT,APOPT1,ZNF449,CAPZA1,BCL2,KIFAP3,HP1BP3,VOPP1,ISG15,CAND1,GNAS,TSC1,RBM25,CDCA5,ZFP90,RBBP4,NIPSNAP2,HNRNPDL,ZBTB24,SMARCD1,MBD1,WASF2,TOMM20,IFI27L1,GNPNAT1,MPHOSPH8,FAM92A,HNRNPUL2,NSD3,CHD1,MEAF6,MIEF1,BABAM2,AKAP8,PARL,RPN2,CHTOP,F2R,SCYL3,TMEM14C,ABI1,HTRA2,MOSPD1,RLIM,FAM172A,ZNF500,PSMB7,NLN,WIPF1,BOLA1,ERBIN,BUD13,NDUFB1,PEF1,EIF3G,TAB2,CHCHD1,TULP3,WDR59,CANT1,SCARB1,USP11,SMURF1,CDS2,MRPL42,EYA1,CDK2AP2,MRPS26,LETMD1,KLF13,MAN1A1,FBXO5,GART,PELO,BRD7,MRPL11,SAMD4B,ZDHHC18,GTF3C6,POLR3GL,WDR81,MEN1,ZNF407,MFN2,COX8A,ZRANB2,SRSF3,MBD6,IDH3B,TATDN1,ATP6V1C1,TSC2,LACTB2,CMTM6,RBM4,ZNF275,RPL23A,CDKN2C,NAPG,USF1,MECR,AP1M1,UPRT,CRY2,ECD,MOB1A,RNF26,TIPARP,LRRC59,RHBDD2,MGAT5,MRPL57,BAK1,ZNF559,RHOBTB3,GABPA,NUTF2,COA7,ARF4,GINS4,BOLA3,AHNAK,RAD18,RNASEL,CHPF2,OAZ1,SMNDC1,PDCD4,NXT2,HIVEP3,CLSPN,RHOC,DHX9,PDCD7,PSMD9,COPB2,CD59,TFAP4,RNFT1,RBM34,MEGF8,FBXO7,EFTUD2,MYDGF,CPSF4,MRPL21,LUC7L2,SRSF11,EIF3L,MAPKAPK3,MTA2,SF3B6,ERO1A,MTFR2,USP10,ITM2A,SSR2,BCLAF1,MTX1,SFXN5,TXNDC16,CFAP20,ZNF830,MRPL3,NUP58,ALS2,FAM72A,TRIM41,KARS,GGNBP2,ANK3,PTTG1,TPX2,DAZAP2,GLRX3,STMN1,SH3BP1,MTA1,UBA5,CLCN6,NABP1,INTS12,MICU2,RPRD1B,CGGBP1,CPNE1,SEC61B,POLR2L,FAM118B,KAT7,GOPC,E2F3,CIRBP,CRNKL1,PFKFB3,GORAB,RAB1A,PPP2CA,KIF2A,ALDH3B1,LSM6,RNF38,SNRPG,CENPBD1,DMWD,USP13,ZFP91,TRMT6,IP6K2,WDR5,SLC25A43,PMVK,IFT27,NEIL2,SAPCD2,RRP36,RPA2,PSMD2,CLIC4,PDCD10,COQ4,ITGB8,ARF5,GTF2H2,UTP20,MAGT1,GPS2,DBI,SSNA1,CD81,WDR13,FANCI,PAPOLA,CREM,TET3,FANCL,TIMM23,GLIS2,IL6ST,INTS1,POP7,SLC44A1,MTPN,PLK1,RPP25,RBX1,APH1A,RAD51AP1,ZBED5,PSMG1,UBE2V1,EAF2,KRTCAP2,LUC7L,LSG1,NECAP2,ALG3,AGPAT2,CHD3,ZNF367,E2F4,PRPF4,KPNA2,BEND6,CLN3,FAM208A,NGLY1,POT1,MYL12B,CCDC137,RMND5A,HJURP,NEMP2,PHB2,DNAJB2,NKD2,SDC2,KLC1,CDK13,COX4I1,DNAJB1,RAB6A,CNOT11,ARID1B,C1GALT1,MLX,ZNF746,ARL6IP1,CTR9,ICE2,NIPSNAP1,ABHD2,DCAF8,ACSL3,LDB1,ARMC8,NPIPA1,RBM38,RMC1,NMT2,IRF5,RPL36,HAUS8,PAXX,MBIP,ORMDL2,COX7A2L,LAMTOR4,ZDHHC7,SIL1,DTD1,UNC13C,BCCIP,SART1,TRAF7,NDUFAF2,TOR1AIP1,ZNF416,LAGE3,ZFYVE21,RRAGC,ZNF121,OIP5,NRF1,ABRAXAS2,WDR44,PPME1,PIN1,RPAP1,LMAN1,AHCYL1,TOP1MT,STRAP,ZNF583,SNX25,ARHGAP17,POLR2G,ZNF780B,PPT1,NUP155,DCLRE1C,MRPS14,RHBDF2,SUGP1,AFDN,RBL1,FASTK,UBXN2B,STK38,AP1S1,SPRYD4,H3F3A,CHID1,SMAD4,RAD51D,SLC30A9,CMAS,AGO2,HMGN3,NCAPG,SCYL2,FZD6,HERC3,GTPBP3,CTSS,ORC3,YTHDC1,ACP2,HMGN5,CSRP1,PRKDC,ABCF2,TUFM,RANGAP1,PNPLA8,HAGH,API5,ZFR,SEC23IP,E2F1,RBPJ,PDCD6IP,MAX,LUZP1,ADAM10,CXXC1,TSC22D3,AP3M2,CUL1,GYG1,NANS,OAT,MYEF2,PA2G4,MTFR1L,NOL11,FIZ1,ZNF200,AP2B1,MARCH2,SLC26A2,SRSF10,SRP72,KLF10,LACTB,SUPT20H,RFC2,CBFB,RAB2B,PRIM1,HHEX,BRD2,LUC7L3,RPS14,MRPL27,BTF3,PTPDC1,SLF1,NMD3,CCDC59,PTOV1,COX5B,DNAJC5,SCOC,POLR2K,PRKAA1,TATDN3,PXMP2,PRPF39,PSEN1,ZNF79,PDXDC1,VPS25,NDUFS7,YY1AP1,C12orf10,FAM192A,RPN1,LHX8,ARPC5,ZNRF2,TPST1,CYC1,MRM3,FDFT1,GID8,PIGT,CPQ,WDR1,ZNF574,C1orf35,EXOSC9,ARID1A,PTTG1IP,FXR1,GOSR1,MAP2K2,TWISTNB,AKAP1,XRCC5,HMGN2,PI4K2A,CAT,SEC31A,DERL1,MTHFD2,CEBPG,ARAP1,USP32,CABIN1,SMPD4,GPI,CYTIP,TP53RK,RAB11B,UROD,SLC39A13,POMP,BCL2L1,NUDT19,DECR1,RALB,SIAH1,LPIN2,MRPS27,TTC3,RNASEH2A,CFL1,ANKLE2,VDAC2,EDF1,ERC1,ANKZF1,RAD51C,ZNF282,DSN1,DDOST,HINT1,DGCR8,RAB24,SAFB,NCLN,BEND3,EYA2,DYNC1LI2,MANBA,B4GALT5,FAM76A,TKT,CBLL1,ARGLU1,POFUT1,HEATR5B,HLA-A,EBP,RFWD3,NDUFA2,FUT8,PTPN11,MRPL54,FEM1B,CNN2,NDUFA3,MTX2,MSH6,PDLIM2,RFXANK,GUF1,SPPL2B,ZHX1,OAZ2,NDUFS5,WDR91,GPR89B,HIGD2A,RORB,POLA2,ZNF76,MTX3,COPA,KMT2E,UQCR10,HMGXB3,ABCB10,COMMD5,MAP1LC3B,ATP5PF,DST,RAB35,SIVA1,GPATCH1,TCEA1,CARMIL1,DRAM2,DEAF1,SNRNP200,LAP3,NCK1,VHL,SREK1,ARHGDIB,PITPNB,BRWD1,PPM1G,SH3GLB2,CRCP,BAZ1B,CAB39,STK11,CLU,CHEK2,MRPL13,CHPT1,DCAF5,CAPN1,UBE2D3,NSMCE4A,PPP1R12A,ZCCHC8,GORASP1,UBXN1,NACA,RPL15,PCSK7,EPN1,THRAP3,QSOX2,TTF1,NUP205,PRPF18,DTL,MED10,PYURF,ZRANB1,MCPH1,SLC12A2,ATP6V0D1,CSNK1G3,ATP5IF1,CREG1,NUDT4,ERLIN1,RPL6,VKORC1,SLTM,EVC2,KLHL15,SIAH2,SLC16A1,DNPH1,EHD4,SNRNP70,C11orf1,APOL2,N4BP2L2,SNX27,CHMP2A,CORO7,PMS2,CLCC1,EXT2,MXD1,USP5,HNRNPA2B1,SAP130,NVL,PPP6C,CYB5R1,UTP4,ZNF770,EBAG9,RNF25,PCGF6,FAM72B,PON2,VPS26C,HNRNPR,STAT6,MAPK1,PDF,TMEM33,NAT14,DNAJC2,TRIP12,SHPRH,SCYL1,VPS45,GFM2,SPPL2A,FASTKD3,FGFR3,MZT2A,PPIG,KMT5A,ZDHHC13,NABP2,H2AFY,NDUFS8,ATG13,FBL,SLC35A1,MICAL3,B3GALT6,TGFB1,ELOVL5,PPP1R9B,HEMK1,TIMMDC1,HELB,PSPC1,MIER1,NADK2,NDRG3,CDK11A,ACAT1,KMT2B,CENPT,PLOD3,RAB14,ADD1,KDM4A,MRPS15,XIAP,DHX8,GLUD1,ANKRD23,PABPC4,CDK5,CALM2,PSMD1,NEK6,NSRP1,RABGAP1L,SRSF4,KCNAB2,PCBP2,MLST8,PLK3,ZNF672,MRPL43,HSDL1,TOPORS,MCL1,PPFIA3,SMC2,ICMT,SLC50A1,STOML2,LIMK1,ZNF689,PRDX5,VIPAS39,ATE1,MLYCD,ST3GAL2,ATP6V0C,FBXL3,TFDP2,E2F2,PFKP,AAAS,DDX42,SSRP1,MRPL9,MRPS2,TOP2B,TMED3,DDRGK1,RAVER2,GNS,INTS7,MCM5,PHF14,ZNF326,RTCB,UBE2QL1,NAGPA,CYFIP1,TIMM8B,ETV3,TSPYL4,DHX29,TEX10,MAN1B1,RPS10,CBFA2T2,ABCF1,RHOB,PTPRF,SCARB2,OSBPL11,CCDC86,CSK,DUSP3,MDH1,HEXA,SGF29,RNF139,SNX14,ZNF296,FAM208B,TRERF1,UBR2,CHD1L,ACTR3,WDTC1,MYH9,CREBL2,NIPA2,PRKACA,SAFB2,STAM,RAB21,SP100,ZKSCAN1,DDA1,NUP107,ANKRD13C,MAVS,ATF2,RBM15,DCTN1,SHOC2,PSRC1,INTS13,WBP2,ATP6V0A1,NUSAP1,DNAJA1,NDUFA7,TAZ,TAF2,SEC61A1,WDR7,RBMS1,FUS,GEN1,COIL,GALK1,ZNF786,RPS2,TRAK1,JMJD6,AKT1S1,KRI1,FBXO3,GATC,NDUFB4,PPP1R8,PRDM4,GTSE1,GEMIN6,DCP1A,S100A6,NUDC,PDPK1,MOB4,TNFAIP3,GALC,ZNF512,MRPS10,DDX39A,RPA1,ZNF862,ZNF180,KEAP1,POLE,TATDN2,PITX1,CAPN7,LRPPRC,PML,HMGB2,USF2,ANAPC4,DDX47,MCCC1,CDIPT,SEC16A,KCMF1,SSR1,LIN9,PCNA,ZNF639,TRMU,ETV6,PIK3R2,MYBL1,CCAR1,MRPL32,BAZ2A,PBXIP1,TLK1,MRPL12,EZR,LRP5,BRCA1,PRKRA,STX16,EPB41,OPTN,QRSL1,DHFR2,PIEZO1,OSGEPL1,NUDT11,NAA60,GEMIN7,LZTR1,RACGAP1,PPP3CB,B4GALT4,RLF,RAPGEF6,SNRNP25,RB1,VASP,MED8,TIGAR,VMP1,PPIL2,TIMELESS,ALDH18A1,TMEM8A,PREB,ABCC1,TRAPPC9,MEMO1,KRAS,RTF1,UBE4B,NFATC2IP,ARPC1A,ZNF174,PSMC4,GOLGA4,PALB2,SYNCRIP,NIPA1,TIGD2,RNF114,FOXM1,MRPL39,XAB2,SUMO2,DUSP22,COMMD8,RPL11,CSDE1,MDM2,CORO1A,MINPP1,POC5,DVL2,GM2A,PSMA8,COQ10B,CPOX,TIGD5,SLC26A6,PRPF3,TXNL4A,RPSA,SRSF1,DNAJC10,SCAP,ZNF700,TIMM17A,TOMM6,LTA4H,AP2S1,INTS2,CTDP1,MIF4GD,CDT1,ARID5A,SUMF1,GGA2,CSNK1A1,AP3S1,RMI1,TFRC,PTPN2,IRF4,STARD9,GSTK1,NDUFV1,SLC1A4,CWC27,SLC35B4,DDX31,ABCD1,SNX2,ZMYM5,CHCHD6,CDKN2AIPNL,KPNA4,BIRC5,TFE3,SNAP29,CDCA7L,PKD2,ACADM,CHMP7,SAT2,GCSH,ZNF496,TMEM109,TAP1,NHLRC3,IKBIP,KIFC1,DBNDD1,CYB5RL,PARPBP,CDC25B,DNMT1,NOL12,USO1,AKT2,NOL8,GNG7,ELOA,MRNIP,AURKB,MCFD2,SLC25A5,MAK16,STT3A,TMED10,PSMD8,EIF2D,ITGB1,PTPN7,UQCRH,RRS1,ARRB2,RTN3,SVIP,PPIB,MUT,GMFG,HLA-E,NDUFA4,MAN2B1,METTL3,NDUFS4,RNF121,MEX3C,KLF16,HDAC7,DAD1,BDH1,PCYT2,GNAI2,TERF2,MORC3,NOA1,PKM,TOMM40,PATL1,PSMB3,ADSS,SERTAD2,SERF2,ZFP92,NSF,DCK,ERGIC3,ACLY,LPCAT4,VCPIP1,MAP3K5,PPP6R3,PPP6R2,YY1,CDK2,RNF14,ZC3HAV1,SYS1,ZBTB37,URB2,MAGED1,ADPGK,SLC25A44,AP1B1,SDHA,PHC2,CRKL,TERF2IP,MOAP1,CYHR1,ZNF75D,SHC1,UCHL5,TMBIM1,MRM2,CDKN2AIP,CCT2,HMGN4,LYRM1,CDC23,AP4E1,PRDM11,VEZF1,PPP2R5A,STAT1,PPA2,TRIM32,R3HCC1L,TCF3,MRI1,BRAP,AGPAT3,MYNN,SDF2L1,SPR,RAB11A,REEP5,FOXO3,MAD2L2,PIP5K1C,RBM17,MAT2B,PTEN,CENPJ,TAGLN2,OSTC,MAP3K14,CREB1,NCOA2,PACS2,SMC4,RNASEH2C,NEK7,NET1,PARP4,TBRG4,ANAPC2,RPL27A,YIF1A,SGSH,HGS,ATP5MC3,MFAP1,CCDC69,BRWD3,ESYT2,NPHP4,HNRNPAB,ST13,ZNF107,KIF2C,AGFG1,SIRT2,USP48,UBQLN2,SNRPD3,FKBP2,CUTC,UBLCP1,ZNF804A,RAP1A,THADA,EIF4A3,AP3S2,DPYSL2,AKR1B1,NDUFB9,RP2,TECR,ARID4A,TIMM50,TDP1,DPM1,FOPNL,SLC25A22,WDR82,STK17B,DHX15,CHAF1A,GEMIN5,TIMM29,COPS6,RPS26,PSMC1,TBC1D12,TM9SF4,ZNF768,UFC1,MED13L,TIA1,MEF2A,EPHX2,PITHD1,RHBDD1,NFATC3,BANF1,BUD31,ZNF335,YBX1,KNTC1,UBE3C,ACAD8,ZNF189,ALDH9A1,KDELR1,TSTA3,CIC,OXR1,PSMA1,SEPT7,NAP1L1,NSMF,ODF2,NUP62,PITPNA,NAA20,PTDSS1,MZT2B,PDSS2,TMEM106C,IMMT,ASH1L,CHERP,WDYHV1,PLAGL2,IRF3,TWF2,ANKRD28,ANKLE1,SAR1A,APOOL,PDIA6,ACSL5,DMAC2,TOR1AIP2,GFER,RAD54B,DAP3,ZNF317,GADD45B,AKNA,REEP4,CBX4,MIF,KIF3B,GOLPH3L,CASP6,TOR3A,SRGN,DBF4,TIMM21,MFSD10,CTNNBL1,YIF1B,SLC25A1,GINS1,CSNK1G2,TELO2,HMGN1,NASP,ASPM,ATP5MF,SYMPK,TARS,SNRPA,MAPK3,HSPA1B,CNOT9,HLA-B,PLAA,ATAD2,ZNF330,OSBPL8,PREPL |
| 1.587e-99 | -227.49 | nuclear part | cellular component | GO:0044428 | 4423 | 1112 | 18223 | 2701 |
ZBTB10,TGOLN2,CCNL2,RBM4,RPL23A,USF1,RAD23B,CRY2,ECD,MOB1A,ZNRD1,LRRC59,RHBDD2,FTSJ3,ERCC1,GABPA,EHMT1,HNRNPF,WDHD1,NUTF2,MCM2,GINS4,SMAD2,RAD18,RPS27A,OGT,RNASEL,SMAD1,ANXA11,SMNDC1,NXT2,CLSPN,GGA1,DHX9,PDCD7,PSMD9,PARN,CDC73,TMEM179B,SMC3,RBM34,EFTUD2,TNPO3,GEMIN4,CPSF4,MVP,PABPC1,NUP85,LUC7L2,SRSF11,EIF3L,AGGF1,FOXK1,MAPKAPK3,MTA2,SF3B6,GTPBP4,USP10,BCLAF1,ELK1,MAGED2,KPNA1,ETS2,WIPI2,ZNF830,NUP58,TRIM41,TPX2,INO80E,DAZAP2,CPNE3,AHCTF1,ZNF420,MTA1,TBC1D14,GMEB1,NABP1,NSFL1C,INTS12,ZC3H3,RPRD1B,CGGBP1,CPNE1,POLR2L,EID1,FAM118B,KAT7,CRNKL1,E2F3,CIRBP,POLR2D,HTATIP2,PFKFB3,GORAB,MEF2D,GSTCD,KIF2A,LSM6,NSMCE2,RNF38,SNRPG,PPP5C,TUBB,USP13,SRSF6,ZFP91,TRMT6,HABP4,FLOT1,ABHD14B,ATG2B,IP6K2,WDR5,RRP36,SAPCD2,NEIL2,TUT4,RPA2,PSMD2,CLIC4,HUWE1,ZNF260,KANSL2,GTF2H2,MED22,DDX24,USP42,LLPH,UTP20,SH3BP5,GPS2,PARG,ACOX1,AEN,PARP10,WDR13,RBM8A,SNX15,ENSA,NENF,RUFY1,TRIM65,FANCI,PAPOLA,KRR1,PRNP,FANCL,NUP210,GLIS2,INTS1,SLC44A1,POP7,NOC2L,RYBP,PLK1,RPP25,PTPN18,MIOS,RBX1,RAD51AP1,SNRPB,ZBED5,PSMG1,CDC6,UBE2V1,PBRM1,EAF2,UTP3,LUC7L,USP21,LSG1,CHD3,GRIPAP1,ZNF367,E2F4,PRPF4,KPNA2,FAM208A,POT1,CCDC137,ZNF564,FUBP1,ZCCHC9,NEMP2,HJURP,PHB2,DNAJB2,CENPF,CDK13,DNAJB1,ARID1B,SUB1,MLX,MBD2,XPA,CTR9,RBM3,ICE2,GLE1,DCAF8,LDB1,METTL22,APPL1,NPIPA1,HAUS8,RXRB,RPL36,SDHB,PAXX,MBIP,PCM1,COX7A2L,DTD1,RUVBL2,BTBD10,BCCIP,USP7,SART1,ARID2,TOR1AIP1,LAGE3,PCBP1,OIP5,NRF1,PSMA6,ZNF473,BRPF3,KMT5C,ABRAXAS2,PIN1,PPME1,TARDBP,TOP1MT,STRAP,SPIDR,CTDSP2,PRPF19,KDM3B,BIRC3,POLR2G,PPIE,NUP155,DCLRE1C,TMEM201,SUGP1,AFDN,DHX16,RBL1,UHRF2,CHMP4B,XRCC3,H3F3A,SMAD4,RAD51D,NIFK,CMAS,C19orf53,MCM10,AGO2,CDCA8,GTF3A,HMGN3,PAGR1,TUBGCP2,DNAJB9,POLR1B,ORC3,RBM15B,YTHDC1,PPAN,RPRD1A,BTAF1,PRKDC,TOP3A,RANGAP1,PCGF1,API5,DDX23,L3MBTL3,NEIL3,BBX,E2F1,RBPJ,TAF12,NR2F2,HIPK3,IFI16,NUP188,MAX,H2AFZ,PNISR,CXXC1,CUL1,USP39,UBE2I,OAT,PARK7,PA2G4,NOL11,TRA2B,TAF5L,SMARCE1,CDC5L,SRSF10,NSUN2,SUPT20H,USP22,RFC2,CBFB,CLNS1A,EIF3A,PRIM1,ZMYM3,DOT1L,IWS1,MKNK1,KIF18B,BRD2,RPS14,TPP2,LUC7L3,PTPDC1,SLF1,CCDC59,ZMAT3,NMD3,B4GALT2,PRPF38B,RECQL,C9orf78,EWSR1,SCOC,POLR2K,PRKAA1,RRM1,SUPT7L,PRPF39,PSEN1,VPS25,YY1AP1,NPLOC4,WDR48,C12orf10,TMEM250,EXOSC7,MSH2,TNRC18,GID8,EIF5A,GCC2,PRIM2,ELL2,RPS24,EXOSC9,ARID1A,FXR1,PTTG1IP,CCT8,TWISTNB,PHF6,XRCC5,EPOP,RBMX,MED15,PIAS2,ARAP1,CEBPG,APPL2,CABIN1,GPI,CYTIP,NDC1,ATXN3,TP53RK,RAF1,UROD,POMP,BCL2L1,C2orf49,DECR1,CCNA2,TAP2,TTC3,RNASEH2A,AQR,TP53BP2,ILKAP,CDK12,CFL1,SAP30,BRD4,NARF,ELP4,EDF1,PKMYT1,TRIM28,SUPT16H,RAD51C,DSN1,HINT1,DGCR8,CERS6,SAFB,ATF6,BEND3,XRCC4,EYA2,PRPF4B,TKT,FAM76A,CBLL1,ARGLU1,EBP,RFWD3,CCNK,DNAJC8,PTPN11,FEM1B,CARF,CITED2,MTX2,MSH6,KAT2A,RFXANK,BMS1,KLF6,SPPL2B,CBX3,ZHX1,DUSP11,DDX5,WDR62,TAF6,PURA,DEF6,DDB1,IPO4,RORB,POLA2,CCNC,LYRM4,KMT2E,COMMD5,BRIX1,MRPL19,SF3B2,DST,SIVA1,JAZF1,RPF2,GPATCH1,TCEA1,SLC35C2,CARMIL1,CARM1,SRPK2,DEAF1,LARS,SNRNP200,LAP3,VHL,RIOX2,SREK1,KMT2C,ASF1B,EIF4ENIF1,BRWD1,NIP7,U2SURP,PPM1G,SH3GLB2,CRCP,BAZ1B,STK11,CHEK2,DCAF5,UBE2D3,NSMCE4A,PPP1R12A,ZCCHC8,PM20D2,THRAP3,RGS2,QSOX2,TTF1,PRPF18,NUP205,LYAR,DTL,MED10,EI24,ZRANB1,MCPH1,POLR2I,SUGP2,SYVN1,SLTM,DAPK3,MASTL,UAP1,SIAH2,YWHAZ,CTSA,SNRNP70,C11orf1,TSEN15,TCF12,SNX27,CHMP2A,PRKAB1,PMS2,SMARCA4,ORC1,MXD1,HNRNPA2B1,SAP130,RRN3,CD3EAP,NVL,EXOSC1,UTP4,CSTF1,POU2AF1,UBQLN4,NXT1,SMU1,PCGF6,LSM8,ATXN1,BICD2,TOLLIP,MBD3,FANCE,RPS9,ALKBH6,HNRNPR,STAT6,ARNTL,ANP32E,FKBP5,MAPK1,TMEM33,CWC25,DNAJC2,TRIP12,SHPRH,RAE1,NUP54,PAWR,PIP4K2A,MZT2A,KLHL20,KMT5A,PPIG,NABP2,H2AFY,ANP32A,FBL,STAT3,MICAL3,PPP1R9B,DCAF6,TIMMDC1,PSPC1,HELB,MIER1,RFFL,RCOR1,PRMT2,LEMD2,UPF1,KMT2B,CENPT,ZMIZ1,TERF1,ADD1,MRPS15,KDM4A,XIAP,DHX8,PPP1R16B,ANKRD23,MIS12,CDK5,PSMD1,NEK6,NSRP1,SRSF4,PDS5B,NUP153,SENP1,PCBP2,MLST8,PLK3,ZNF672,AATF,MCL1,TOPORS,SMC2,STOML2,BRMS1,PWWP2B,LIMK1,FBXL3,TFDP2,E2F2,AAAS,SSRP1,DDX42,PHF23,TOP2B,EZH1,LMNA,DDRGK1,DDX56,INTS7,MCM5,RTCB,ZNF326,ETV3,RB1CC1,PRRC2A,ZMYND11,TEX10,MYBL2,RPS10,SRSF5,MPG,MATR3,ABCF1,OSBPL11,CCDC86,POLR2J,DUSP3,SETD3,SGF29,ZNF207,FAM208B,SARNP,TRERF1,IVNS1ABP,CHD1L,TMEM97,RMI2,WDTC1,MYH9,RXYLT1,NUF2,SAFB2,PRKACA,APP,PRKD3,CLUAP1,SP100,ATP2A2,UTP18,DUT,DDA1,NUP107,ANAPC7,FAM76B,RBM15,ATF2,RNF169,DCTN1,SHOC2,PSRC1,INTS13,RNPS1,WBP2,ATP6V0A1,NUSAP1,CDCA2,DDX17,TAF2,CDC16,HIPK2,FUS,PDXK,ZBTB11,GEN1,COIL,RPS2,JMJD6,GMCL1,AKT1S1,ETS1,PNO1,KRI1,FBXO3,ADD3,SUV39H2,NDUFB4,PPP1R8,PRDM4,GEMIN6,GTSE1,S100A6,HNRNPM,NUDC,PDPK1,PPP3CA,POLK,DDX39A,RPA1,KEAP1,POLE,TATDN2,PITX1,MAPK6,PML,LRPPRC,HMGB2,USF2,ANAPC4,FAF1,DDX47,THOC1,CSNK2A1,EBNA1BP2,GIT2,LIN9,PCNA,ZNF639,ETV6,TRMU,XRCC2,ZFYVE27,MCMBP,CCAR1,METTL1,SP3,EXOSC6,BAZ2A,EZR,BRCA1,PRKRA,ANLN,RHEB,OPTN,TIMM13,CDCA4,TONSL,NRM,ACTB,ZNF45,SINHCAF,GEMIN7,TMUB1,CTCF,RACGAP1,PPP3CB,ASXL2,SNRNP25,RB1,MED8,VMP1,PPIL2,TIMELESS,AFF1,MDFIC,MAML1,NQO2,UTP15,RTF1,ZNF174,PSMC4,SYNCRIP,PALB2,CDC27,SNAP23,TBPL1,PRMT7,ATP5F1A,FOXM1,XAB2,DYNLL1,SUMO2,COPE,HCFC1R1,RPAIN,COMMD8,RPL11,RAD23A,PDK2,ZBTB21,MDM2,TNFAIP8,SAP30L,DVL2,POC5,RPL35,MTMR6,DNAJC9,NFATC2,PRPF3,KDM1B,TXNL4A,USP36,RPSA,SRSF1,CLK3,TIMM17A,PSMD3,MAFK,ZNF436,NCOA1,LTA4H,ZC3HC1,ZNF146,INTS2,CTDP1,CDC40,MIF4GD,CDT1,ARID5A,SMC6,NKRF,CSNK1A1,RMI1,WRNIP1,PTPN2,IRF4,CWC27,SS18L1,DDX31,PTGES3,CENPM,CAMK2G,ZMYM5,PPWD1,FAM50B,CDKN2AIPNL,KPNA4,BIRC5,TFE3,SNAP29,CDCA7L,ACADM,UBE2C,CHMP7,ZNF496,NDUFB6,TMEM109,CCNB1,POLR3K,UTP25,SNUPN,CYB5RL,PARPBP,CDC25B,DNMT1,SEH1L,NOL12,USO1,AKT2,NOL8,MKI67,ELOA,MRNIP,DDX20,AURKB,MAK16,PSMD8,EIF2D,WDR4,PTPN7,RRS1,HDAC2,HSPH1,LIME1,CHTF18,KIF23,NOTCH2,PMF1,METTL3,JMY,HDAC7,BDH1,GNAI2,EEF1D,TERF2,MORC3,DDX28,PHF10,SIGMAR1,KDM3A,PATL1,SF3A2,PSMB3,FAS,SERTAD2,ACLY,PPP3R1,DCAF11,TCOF1,PPP6R3,YY1,CDK2,NRBP1,DNMT3A,TRIP10,SUZ12,SF3B1,URB2,RPS6KA1,OLA1,SDHA,TERF2IP,PHC2,CRKL,CYHR1,KDM2A,UCHL5,CDKN1B,TNPO2,TALDO1,GPX4,MRM2,CDKN2AIP,RFC3,ERF,LYRM1,CUL3,SLBP,CDC23,GAR1,H2AFV,PSMB9,CENPU,NSA2,VEZF1,FAAP100,TBL3,STAT1,H2AFX,PDCD11,CSNK1D,ATMIN,POLQ,NCOR2,R3HCC1L,TCF3,MRI1,BABAM1,BRAP,AGPAT3,BLM,SPR,FOXO3,MAD2L2,PIP5K1C,GTF2F1,RBM17,PTEN,CENPJ,COPS7B,UPF2,MAP3K14,CREB1,UBE2M,NCOA2,SMC4,ZFP64,NEK7,DENND1B,WDR18,ILF3,ANAPC2,MARK2,POLR2A,HNRNPH3,TFDP1,KHSRP,NAXE,ASNA1,BYSL,DDX52,S100PBP,IER2,NOP2,HNRNPAB,NF1,UBN1,ALKBH5,UBE2Z,SIRT2,AGFG1,TAF6L,SNRPD3,USP48,MAPK14,CUTC,SNAPC4,MBD4,UBLCP1,EIF4A3,IMPAD1,METTL14,SRI,AKR1B1,KHDC4,KIF22,RP2,NFU1,OGG1,ARID4A,TIMM50,ELOF1,FYTTD1,COPS8,TRIM8,WDR82,SOX4,DHX15,CHAF1A,UBTF,GEMIN5,PAF1,SPATA2,PQBP1,ATXN2L,COPS6,RPS26,PSMC1,RPS15,AGTRAP,ZNF768,CIB1,MED13L,TIA1,MEF2A,XPO7,SRRT,NFATC3,BANF1,BUD31,ZNF335,YBX1,BCL2,KIFAP3,HP1BP3,CIC,OXR1,PSMA1,ISG15,CAND1,RBM25,NSMF,CDCA5,NUP62,RBBP4,HNRNPDL,MZT2B,SMARCD1,MBD1,ASH1L,MPHOSPH8,CHERP,HNRNPUL2,NSD3,IRF3,CHD1,MEAF6,ANKRD28,ANKLE1,BABAM2,AKAP8,CHTOP,RLIM,ACSL5,ZNF500,PSMB7,TOR1AIP2,ERBIN,BUD13,NDUFB1,DAP3,TAB2,CHCHD1,TULP3,USP11,AKNA,SMURF1,CBX4,MIF,CASP6,EYA1,MRPS26,DBF4,LETMD1,FBXO5,CTNNBL1,BRD7,GINS1,TELO2,GTF3C6,HMGN1,NASP,POLR3GL,MEN1,SYMPK,SNRPA,HSPA1B,MAPK3,ATAD2,OSBPL8,ZNF330,ZRANB2,MBD6,SRSF3,TATDN1 |
| 5.559e-95 | -217.03 | organelle | cellular component | GO:0043226 | 13257 | 2377 | 18223 | 2701 |
HECA,ZBTB10,ABCC10,HEXB,TGOLN2,CCNL2,SYNRG,FBXO22,EEF2K,RAD23B,ATP13A3,DNM2,ZNRD1,FTSJ3,ERCC1,NRAS,EHMT1,KIF15,HNRNPF,WDHD1,MIER2,DIDO1,MCM2,RAB22A,SMAD2,MID1IP1,RPS27A,MYO18A,OGT,MPV17,COX5A,KLHL42,SMAD1,ZNF75A,ANXA11,SLC25A33,SEC61G,GGA1,MUM1,CCZ1,CUTA,RAB23,KCTD17,HAUS4,EIF2AK4,APH1B,PARN,CDC73,MYL6B,TMEM179B,PDXP,SMC3,TNPO3,GEMIN4,MVP,NUP85,PPP6R1,PABPC1,NSUN4,PPA1,IFRD1,AGGF1,FOXK1,RBM42,GTPBP4,MAP7D1,MRPL16,ELK1,RDH11,MAGED2,KPNA1,ETS2,WIPI2,PDLIM5,ACSF2,FAM72D,EXOC3,RHOG,STARD7,C5orf30,VTI1A,INO80E,SLC35B2,RCOR3,LCLAT1,CPNE3,RBM23,ZNF420,AHCTF1,TBC1D14,GMEB1,NSFL1C,SEPT11,ZNF226,GPD1L,ZC3H3,PDCL3,SNX8,ERMP1,EID1,IDH3A,POLR2D,HTATIP2,MEF2D,TMEM147,GSTCD,TANC1,VPS26B,CORO1C,NSMCE2,CAMKMT,PPP5C,PITRM1,TUBB,COMMD10,ZNF445,SRSF6,HABP4,CCM2,FLOT1,ATG2B,ABHD14B,ATP5F1B,HDGFL2,NEXMIF,TUT4,PPP1R3B,GOLM1,ZBTB45,HUWE1,ZNF260,NAA50,ANXA5,LTN1,KANSL2,NAP1L4,ZNF710,ST8SIA2,RPL22L1,MED22,SPTAN1,STAU1,TCTEX1D2,DDX24,TACC1,USP42,MRS2,LDHA,HEBP2,LLPH,RAB3IP,PICALM,SH3BP5,PARG,ACOX1,FAM3C,AEN,PARP10,YWHAH,THAP5,FAM129A,TRIM11,YTHDC2,SNX15,RBM8A,ENSA,NENF,SND1,RUFY1,TRIM65,PRNP,KRR1,RAB8A,NUP210,NOC2L,EIF5,TACC3,RYBP,PTPN18,MIOS,SNRPB,MBLAC2,CDC6,UTP3,PBRM1,USP21,TRAM2,FBXO28,GRIPAP1,ARRDC1,ADAM9,DVL1,NUMB,ZNF564,FUBP1,PARP12,ZCCHC9,CENPF,LAMTOR3,CHCHD2,NCKAP1,RSAD1,SUB1,RINL,SSBP3,KIF13B,MBD2,XPA,AHCY,RBM3,GLE1,MRPL48,HDHD2,NSDHL,CAMSAP1,ZNF761,METTL22,APPL1,BBS12,RXRB,SDHB,PCM1,GALNT2,TMEM168,NLRC5,RUVBL2,BTBD10,MYO9A,ECPAS,CCNB2,USP7,GLT8D1,RPLP2,SUCLG1,ARID2,TMX4,SLC2A1,ATP6V1B2,PCBP1,LYN,BCAP31,MRPL50,PSMA6,ZNF473,ZNF302,KMT5C,BRPF3,TARDBP,BCAP29,CTDSP2,SPIDR,PRPF19,PPIF,KDM3B,MND1,CLCN3,BIRC3,RAB7A,PPIE,CHMP2B,VDAC1,EIF3H,TMEM201,GLOD4,IDE,DHX16,UHRF2,CHMP4B,XRCC3,PARD3,BCL2L12,NIFK,C19orf53,MCM10,MTERF1,KLHL21,PDAP1,TMX3,CDCA8,GTF3A,ARF1,SLC12A9,CDK11B,PAGR1,TUBGCP2,DNAJB9,HOMER1,POLR1B,RNF5,RBM15B,PPAN,RHOA,RPRD1A,BTAF1,TOP3A,ARHGEF12,PCGF1,DDX23,RAB18,TRIM26,PDCD6,ATP6V1D,NEK1,L3MBTL3,FAM110A,NEIL3,CTBS,BBX,IMPDH1,TAF12,NR2F2,PGAM1,ARHGAP23,HIPK3,IFI16,TXN,NUP188,H2AFZ,PNISR,TMEM203,PRKCSH,USP39,UBE2I,PARK7,SLC25A37,GLMP,RAB4A,TRA2B,SUCLG2,CISD2,TAF5L,SMARCE1,ZNF800,CDC5L,ZNF524,SGCE,NSUN2,USP22,CLNS1A,EIF3A,ZMYM3,DOT1L,IWS1,MKNK1,WAS,KIF18B,TPP2,C1orf109,ZMAT3,FAM72C,B4GALT2,PRPF38B,RECQL,C9orf78,EWSR1,GADD45G,RRM1,DNAAF5,ACAP1,B4GALT1,CYCS,SUPT7L,ZNF518A,TMEM165,NPLOC4,CNOT3,SPAG5,WDR48,RTKN,TMEM250,CEP104,EXOSC7,KLHL5,LRRC8D,MSH2,PIGG,OSTF1,FBXL7,MRPL40,TNRC18,SYTL3,APOL1,EIF5A,GCC2,PRIM2,COQ8A,ELL2,RDH10,USF3,MFNG,RPS24,GORASP2,CAPZA2,ADRB2,CCT8,PHF6,PFDN5,GOLGA2,EPOP,RBMX,MED15,PIAS2,APPL2,SAMD8,CDKN2A,NUDT3,ZNF511,NDC1,ATXN3,RAF1,C2orf49,CD320,EPM2A,CCNA2,MTMR4,BRI3,TAP2,TP53BP2,AQR,ILKAP,CDK12,SAP30,BRD4,DRAP1,NARF,ELP4,ABHD11,PKMYT1,SERP1,TRIM28,SUPT16H,EIF3K,CHMP4A,CERS6,ATF6,XRCC4,PRPF4B,NDUFS1,DEPDC1,MECP2,SECISBP2,SPDL1,HMG20A,WWP2,SLC25A36,JAKMIP1,CCNK,DNAJC8,ELP5,AXIN2,CARF,CITED2,ANKRD37,KAT2A,TMEM126B,PACS1,BMS1,KCNQ1,ARSK,MACF1,KIF11,COMMD4,KLF6,SMAP2,FADD,SH3GLB1,MYO1F,CBX3,TMEM127,PPP1R11,DUSP11,DDX5,WDR62,TAF6,ESPL1,PURA,DDB1,DEF6,IPO4,FAM83G,UBL3,CCNC,PIGM,LYRM4,UBE2Q1,PTP4A3,BRIX1,MRPL19,ZNF696,SF3B2,PCYOX1L,CDC42,SYNM,GOT2,JAZF1,HADHB,RPF2,SLC35C2,CARM1,SRPK2,WDR41,LARS,LRBA,TMEM216,RIOX2,SUMF2,KMT2C,OGFR,MPC1,ASF1B,RPL37,MAN2A2,EIF4ENIF1,NIP7,U2SURP,MIA2,ZNF268,VPS4A,ATP6V0E1,PM20D2,XPNPEP3,RGS2,LYAR,EI24,POLR2I,SUGP2,GBA,EIF2A,SYVN1,DAPK3,MASTL,UAP1,NFIL3,YWHAZ,CTSA,TMEM14A,TOB1,TSEN15,ADNP2,TCF12,PRKAB1,MDH2,SMARCA4,ORC1,RRN3,UBXN2A,IARS,CD3EAP,KIF14,EXOSC1,CS,CLTB,DNAL4,CSTF1,CHP1,POU2AF1,UBQLN4,NXT1,PPP1R18,SMU1,LSM8,ATXN1,GLO1,OGDH,BICD2,EDEM2,TOLLIP,FANCE,MBD3,PDHX,RPS9,ALKBH6,SURF4,ARNTL,ANP32E,FKBP5,ABCA1,CWC25,ZNF316,RAE1,DCTN2,NUP54,CHIC2,PAWR,MXD4,DCUN1D4,PIP4K2A,XPR1,FERMT3,KIF5B,KLHL20,SEC24C,RRBP1,DUS2,ARHGEF2,ANP32A,STAT3,MYO5A,TXNL1,COA3,PHF20L1,DCAF6,FAM49B,ATP2C1,RFFL,COG1,RCOR1,PRMT2,TFEB,LEMD2,CTSL,UPF1,ZC3H7B,ZMIZ1,TERF1,HRAS,SLF2,CCDC93,FGFR1OP,TMED7,MAP3K7CL,PIGQ,AGPAT1,CNTROB,PPP1R16B,EDRF1,MIS12,CIPC,PDS5B,NUP153,SENP1,PGAP2,TMEM115,AATF,PLEKHF2,BRMS1,PWWP2B,TRIM47,WDR11,AXIN1,LONP2,NDUFV2,PHF23,EZH1,ITGB5,LMNA,MCTS1,DDX56,EIF2S2,FOXN2,CARS2,PRRC2A,RB1CC1,ZMYND11,PGS1,MYBL2,SRSF5,MPG,MATR3,CYB5A,NCDN,POLR2J,SETD3,TEX30,CNOT6,NDE1,EGLN1,ZNF207,ANKRD27,ABCA3,SARNP,IVNS1ABP,MON1B,RMI2,TMEM97,NIT2,RXYLT1,NUF2,ZNF267,TCF19,KTN1,APP,PRKD3,CLUAP1,ATP2A2,UTP18,GRSF1,DUT,ANAPC7,RNF19A,FAM76B,CLN6,TMEM9,GCC1,RNF169,ATP6V1G1,ENPP4,RNPS1,CDCA2,FKBP3,DDX17,CHCHD3,PEX5,CDC16,HIPK2,MBOAT1,TICAM1,PDXK,ZBTB11,ANXA6,TMBIM4,GMCL1,UBE4A,ETS1,WRB,ZNF92,PNO1,CAPN2,ADD3,SUV39H2,TPCN1,TMX1,LYPLA2,HNRNPM,MFSD12,LDHB,PPP3CA,POLK,JTB,PDE3B,KIF18A,CCDC6,WNT5B,MAPK6,LY75,SLC25A19,PSAP,WDR76,FAF1,SNAPIN,COX15,AGRN,THOC1,GNPDA1,GPBP1L1,PPP1R15B,CSNK2A1,EBNA1BP2,GIT2,BIRC2,ATPAF1,DLG5,ABL2,XRCC2,ZFYVE27,MCMBP,PTPRK,CDC37,SP3,METTL1,EXOSC6,HARS,CYSTM1,ESYT1,ANLN,RAB5B,RHEB,DPYSL3,TBC1D17,TIMM13,CDCA4,TONSL,NRM,NAGLU,ACTB,ZNF45,SINHCAF,C2CD5,TMUB1,CTCF,ASAH1,CRLF3,ASXL2,NUS1,CMTR2,SLC27A4,AFF1,MDFIC,MAML1,CYTH1,NQO2,UTP15,ZDHHC3,SPATA33,MOSPD3,CDC27,SNAP23,TBPL1,PRMT7,ATP5F1A,NDUFA5,CYLD,UGP2,DYNLL1,COPE,HCFC1R1,ZADH2,RPAIN,RAD23A,ABRACL,SEC11A,PDK2,ATP6V0B,ZBTB21,STRBP,TNFAIP8,MRPL34,PDCD2,SAP30L,RPL29,TIMP2,RPL35,BTG2,TUBGCP5,DNAJC9,MTMR6,NFATC2,KDM1B,USP36,MRPL2,ATP1A1,CLK3,PSMD3,MAFK,CEP55,NDUFA11,DNAJC17,ZNF436,NCOA1,SLC25A39,ZC3HC1,ZNF146,CDC40,GOLIM4,SMAP1,SMC6,ARFIP2,NKRF,WRNIP1,SS18L1,CENPM,PTGES3,CAMK2G,MLEC,ZNF202,PPWD1,FAM50B,RHOT2,NEU1,GOLGA7,GLG1,PGRMC1,SPCS3,RPS6KC1,UBE2C,NDUFB6,ZDHHC8,PLXNA1,CCNB1,COMMD6,RIC1,POLR3K,C14orf119,UTP25,ASAP2,SNUPN,SPTSSA,TFG,SEH1L,ATG9A,ARHGAP45,PBK,MKI67,DDX20,AMDHD2,GALNT7,SLC17A5,CCNF,FOXRED1,RBM47,PTER,WDR4,DHTKD1,SARAF,TRAF5,HDAC2,PWWP2A,HSPH1,LIME1,MAPRE1,CHTF18,ADO,KIF23,SLC35B1,NOTCH2,PMF1,COPG2,JMY,FKBP1A,NDUFAF6,SLC31A1,SNX18,ATIC,SLC25A51,ATP6V0A2,PIKFYVE,LPCAT1,EEF1D,TMED2,FTL,PHF10,DDX28,ZNF84,SIGMAR1,PIP4K2C,PLEC,CYFIP2,KDM3A,SF3A2,FAS,ZNF777,QARS,CSNK1G1,DCAF11,PPP3R1,TCOF1,CABLES1,NRBP1,DNMT3A,TRIP10,SF3B1,SUZ12,CAST,RPS6KA1,RAC1,GPR89A,OLA1,SNN,SDE2,GNB2,FLAD1,APLP2,KDM2A,TNPO2,CDKN1B,TALDO1,GPX4,ATP13A1,RFC3,MAPRE2,ERF,TAOK1,CUL3,SLBP,H2AFV,GAR1,PSMB9,POLG2,CENPU,DHX57,SOCS7,NSA2,HSPA4,MRPL55,JAK1,FAAP100,GOLGA8A,TBL3,SEL1L,H2AFX,B4GALT3,PDCD11,CSNK1D,ATMIN,POLQ,POU3F2,NCOR2,ANKRD13D,PKP4,SCAMP3,TWNK,BABAM1,SLC25A12,BLM,GTF2F1,RPL17,CRAT,AHSA1,PRC1,UPF2,COPS7B,SLC38A10,CNOT6L,CNPY3,UBE2M,IFT46,TSHZ1,ZFP64,STRIP1,DENND4C,DENND1B,WDR18,RPL8,ILF3,RHOT1,MARK2,TSR2,ECH1,POLR2A,PRDX1,PLD3,NUCB1,C1orf131,PRDX3,PFDN4,CCZ1B,HNRNPH3,TFDP1,STX18,NAXE,KHSRP,ASNA1,CPEB2,VPS29,BYSL,DDX52,S100PBP,ADA2,MIB2,IER2,PTMS,NOP2,UBN1,NF1,ALKBH5,MOGS,UBE2Z,TAF6L,BECN1,MAPK14,SNAPC4,RNF103,BCAT2,MBD4,CYREN,CMSS1,METTL14,IMPAD1,ZNHIT6,RCSD1,PHTF1,SRI,KHDC4,KIF22,ZBTB22,NFU1,OGG1,TRIM14,ELOF1,COPS8,FYTTD1,TRIM8,SOX4,ABHD5,CXXC4,UBTF,PAF1,UEVLD,SPATA2,PQBP1,IARS2,ATXN2L,ROCK1,GALNT10,STARD3NL,CEP170B,RPS15,PIGN,AGTRAP,CIB1,CDIP1,XPO7,SRRT,APOPT1,ZNF449,CAPZA1,BCL2,KIFAP3,HP1BP3,VOPP1,ISG15,CAND1,GNAS,TSC1,RBM25,CDCA5,ZFP90,RBBP4,NIPSNAP2,HNRNPDL,ZBTB24,SMARCD1,MBD1,WASF2,TOMM20,IFI27L1,GNPNAT1,MPHOSPH8,FAM92A,HNRNPUL2,NSD3,CHD1,MEAF6,MIEF1,BABAM2,AKAP8,PARL,RPN2,CHTOP,F2R,TMEM14C,SCYL3,ABI1,HTRA2,MOSPD1,RLIM,FAM172A,ZNF500,PSMB7,NLN,WIPF1,BOLA1,ERBIN,BUD13,NDUFB1,PEF1,EIF3G,BTBD1,TAB2,CHCHD1,TULP3,WDR59,CANT1,SCARB1,GAS2,USP11,SMURF1,CDS2,MRPL42,EYA1,CDK2AP2,MRPS26,LETMD1,KLF13,MAN1A1,FBXO5,GART,PELO,BRD7,MRPL11,SAMD4B,ZDHHC18,GTF3C6,POLR3GL,WDR81,MEN1,ZNF407,MFN2,COX8A,ZRANB2,SRSF3,MBD6,IDH3B,TATDN1,ATP6V1C1,TSC2,LACTB2,CMTM6,RBM4,ZNF275,RPL23A,CDKN2C,NAPG,USF1,MECR,AP1M1,UPRT,CRY2,ECD,MOB1A,RNF26,TIPARP,LRRC59,RHBDD2,MGAT5,MRPL57,BAK1,ZNF559,RHOBTB3,GABPA,NUTF2,COA7,ARF4,GINS4,KRIT1,BOLA3,AHNAK,RAD18,RNASEL,CHPF2,OAZ1,SMNDC1,PDCD4,NXT2,HIVEP3,CLSPN,RHOC,DHX9,PDCD7,PSMD9,HAUS2,COPB2,CD59,TFAP4,RNFT1,RBM34,RIMS3,MEGF8,FBXO7,EFTUD2,MYDGF,CPSF4,MRPL21,LUC7L2,SRSF11,EIF3L,MAPKAPK3,MTA2,SF3B6,ERO1A,MTFR2,USP10,ITM2A,SSR2,BCLAF1,MTX1,SFXN5,FNTA,PDLIM1,TXNDC16,CFAP20,ZNF830,MRPL3,NUP58,ALS2,FAM72A,TRIM41,KARS,GGNBP2,POC1A,ANK3,PTTG1,TPX2,DAZAP2,STMN1,GLRX3,SH3BP1,MTA1,UBA5,CLCN6,NABP1,INTS12,MICU2,RPRD1B,CGGBP1,CPNE1,ULK3,SEC61B,POLR2L,FAM118B,KAT7,GOPC,E2F3,CIRBP,RPL38,CRNKL1,PFKFB3,GORAB,RAB1A,PPP2CA,KIF2A,ALDH3B1,CCDC14,LSM6,RNF38,SNRPG,CENPBD1,DMWD,USP13,MZT1,ZFP91,TRMT6,IP6K2,WDR5,SLC25A43,PMVK,IFT27,NEIL2,SAPCD2,RRP36,RPA2,PSMD2,CLIC4,PDCD10,COQ4,ITGB8,ARF5,GTF2H2,UTP20,MAGT1,GPS2,DBI,SSNA1,CD81,WDR13,FANCI,PAPOLA,CREM,TET3,FANCL,TIMM23,GLIS2,IL6ST,INTS1,POP7,SLC44A1,MTPN,PLK1,RPP25,SEPT9,RBX1,APH1A,RAD51AP1,ZBED5,CKAP2L,PSMG1,UBE2V1,EAF2,KRTCAP2,LUC7L,LSG1,NECAP2,ALG3,AGPAT2,CHD3,ZNF367,E2F4,PRPF4,KPNA2,BEND6,CLN3,FAM208A,NGLY1,POT1,MYL12B,CCDC137,RMND5A,HJURP,NEMP2,PHB2,DNAJB2,NKD2,SDC2,KLC1,CDK13,COX4I1,DNAJB1,RAB6A,CNOT11,ARID1B,C1GALT1,MLX,CCP110,ZNF746,ARL6IP1,CTR9,ICE2,NIPSNAP1,ABHD2,DCAF8,ACSL3,LDB1,ARMC8,NPIPA1,RBM38,RMC1,NMT2,IRF5,RPL36,HAUS8,PAXX,MBIP,ORMDL2,COX7A2L,LAMTOR4,ZDHHC7,SIL1,DTD1,UNC13C,BCCIP,SART1,TRAF7,NDUFAF2,TOR1AIP1,ZNF416,LAGE3,ZFYVE21,RRAGC,ZNF121,OIP5,NRF1,ABRAXAS2,WDR44,PPME1,PIN1,RPAP1,LMAN1,AHCYL1,TOP1MT,STRAP,ZNF583,SNX25,ARHGAP17,POLR2G,ZNF780B,PPT1,NUP155,DCLRE1C,MRPS14,RHBDF2,SUGP1,AFDN,RBL1,FASTK,UBXN2B,STK38,AP1S1,SPRYD4,H3F3A,CHID1,SMAD4,RAD51D,SLC30A9,CMAS,AGO2,HMGN3,NCAPG,SCYL2,FZD6,HERC3,GTPBP3,CTSS,ORC3,YTHDC1,ACP2,HMGN5,CSRP1,PRKDC,ABCF2,TUFM,RANGAP1,PNPLA8,HAGH,API5,ZFR,SEC23IP,E2F1,USP20,RBPJ,PDCD6IP,MAX,LUZP1,ADAM10,CXXC1,TSC22D3,AP3M2,CUL1,GYG1,NANS,OAT,MYEF2,ANKRD26,PA2G4,MTFR1L,NOL11,FIZ1,ZNF200,AP2B1,MARCH2,SLC26A2,SRSF10,SRP72,KLF10,LACTB,SUPT20H,RFC2,CBFB,RAB2B,PRIM1,HHEX,BRD2,LUC7L3,RPS14,MAP4,MRPL27,BTF3,PTPDC1,SLF1,NMD3,CCDC59,PTOV1,COX5B,DNAJC5,SCOC,POLR2K,PRKAA1,TATDN3,PXMP2,PRPF39,PSEN1,ZNF79,PDXDC1,VPS25,NDUFS7,YY1AP1,C12orf10,FAM192A,RPN1,LHX8,ARPC5,ZNRF2,TPST1,DAPK1,CYC1,MRM3,FDFT1,GID8,PIGT,CPQ,WDR1,ZNF574,C1orf35,EXOSC9,ARID1A,PTTG1IP,FXR1,GOSR1,MAP2K2,TWISTNB,AKAP1,XRCC5,HMGN2,PI4K2A,CAT,SEC31A,DERL1,MTHFD2,CEBPG,ARAP1,FAM83D,USP32,CABIN1,SMPD4,GPI,CYTIP,TP53RK,RAB11B,UROD,SLC39A13,POMP,BCL2L1,NUDT19,DECR1,RALB,SIAH1,LPIN2,MRPS27,TTC3,RNASEH2A,CFL1,ANKLE2,VDAC2,EDF1,EML4,ERC1,ANKZF1,RAD51C,ZNF282,DSN1,DDOST,HINT1,DGCR8,RAB24,SAFB,NCLN,BEND3,EYA2,DYNC1LI2,MANBA,B4GALT5,FAM76A,TKT,CBLL1,ARGLU1,POFUT1,HEATR5B,HLA-A,EBP,RFWD3,NDUFA2,FUT8,PTPN11,MRPL54,FEM1B,RPL19,CNN2,NDUFA3,MTX2,MSH6,PDLIM2,RFXANK,GUF1,SPPL2B,RPL32,ZHX1,OAZ2,NDUFS5,WDR91,GPR89B,HIGD2A,RORB,POLA2,ZNF76,MTX3,COPA,KMT2E,UQCR10,HMGXB3,ABCB10,COMMD5,MAP1LC3B,ATP5PF,DST,RAB35,SIVA1,GPATCH1,TCEA1,CARMIL1,DRAM2,DEAF1,SNRNP200,LAP3,NCK1,VHL,SREK1,ARHGDIB,PITPNB,HSPB11,BRWD1,PPM1G,SH3GLB2,CRCP,BAZ1B,CAB39,STK11,CLU,CHEK2,MRPL13,CHPT1,DCAF5,CAPN1,UBE2D3,NSMCE4A,PPP1R12A,ZCCHC8,GORASP1,UBXN1,NACA,RPL15,EPN1,PCSK7,THRAP3,QSOX2,TTF1,NUP205,PRPF18,DTL,MED10,PYURF,ZRANB1,MCPH1,SLC12A2,ATP6V0D1,CSNK1G3,ATP5IF1,CREG1,NUDT4,ERLIN1,RPL6,VKORC1,SLTM,EVC2,KLHL15,SIAH2,SLC16A1,DNPH1,EHD4,SNRNP70,C11orf1,APOL2,N4BP2L2,SNX27,CHMP2A,CORO7,PMS2,CLCC1,EXT2,MXD1,USP5,HNRNPA2B1,SAP130,NVL,PPP6C,CYB5R1,UTP4,ZNF770,EBAG9,RNF25,PCGF6,FAM72B,PON2,VPS26C,HNRNPR,STAT6,MAPK1,PDF,TMEM33,NAT14,DNAJC2,TRIP12,SHPRH,SCYL1,VPS45,MYO9B,GFM2,SPPL2A,FASTKD3,FGFR3,MZT2A,GRK2,PPIG,KMT5A,ZDHHC13,NABP2,H2AFY,NDUFS8,ATG13,FBL,SLC35A1,FRMD8,MICAL3,TGFB1,B3GALT6,ELOVL5,PPP1R9B,HEMK1,TIMMDC1,HELB,PSPC1,MIER1,NADK2,NDRG3,CDK11A,ACAT1,KMT2B,CENPT,PLOD3,RAB14,ADD1,KDM4A,MRPS15,XIAP,DHX8,GLUD1,ANKRD23,PABPC4,CDK5,CALM2,PSMD1,NEK6,NSRP1,RABGAP1L,SRSF4,SPATC1L,KCNAB2,PCBP2,MLST8,PLK3,ZNF672,MRPL43,HSDL1,TOPORS,MCL1,PPFIA3,SMC2,ICMT,SLC50A1,STOML2,LIMK1,ZNF689,PRDX5,VIPAS39,ATE1,MLYCD,ST3GAL2,ATP6V0C,FBXL3,TFDP2,E2F2,PFKP,AAAS,DDX42,SSRP1,MRPL9,MRPS2,TOP2B,TMED3,DDRGK1,RAVER2,GNS,INTS7,MCM5,PHF14,ZNF326,RTCB,UBE2QL1,NAGPA,CYFIP1,TIMM8B,ETV3,TSPYL4,DHX29,TEX10,MAN1B1,RPS10,CBFA2T2,ABCF1,RHOB,PTPRF,SCARB2,OSBPL11,CCDC86,CSK,DUSP3,SLAIN1,MDH1,HEXA,SGF29,RNF139,SNX14,ZNF296,FAM208B,TRERF1,UBR2,CHD1L,ACTR3,WDTC1,MYH9,CREBL2,NIPA2,PRKACA,SAFB2,STAM,RAB21,SP100,ZKSCAN1,DDA1,NUP107,ANKRD13C,MAVS,CEP63,ATF2,RBM15,DCTN1,SHOC2,PSRC1,INTS13,WBP2,ATP6V0A1,NUSAP1,NDUFA7,DNAJA1,TAZ,TAF2,SEC61A1,RPLP1,WDR7,RBMS1,FUS,GEN1,LRP8,COIL,GALK1,ZNF786,RPS2,SESTD1,TRAK1,JMJD6,AKT1S1,KRI1,FBXO3,GATC,NDUFB4,PPP1R8,PRDM4,GTSE1,GEMIN6,DCP1A,SGCB,S100A6,NUDC,PDPK1,MOB4,TNFAIP3,GALC,ZNF512,MRPS10,DDX39A,RPA1,ZNF862,ZNF180,KEAP1,POLE,TATDN2,PITX1,CAPN7,LRPPRC,PML,HMGB2,USF2,ANAPC4,DDX47,MCCC1,CDC42SE2,CDIPT,SEC16A,KCMF1,SSR1,LIN9,PCNA,ZNF639,TRMU,ETV6,PIK3R2,MYBL1,CCAR1,MRPL32,BAZ2A,PBXIP1,TLK1,MRPL12,EZR,LRP5,BRCA1,PRKRA,STX16,EPB41,OPTN,SEPT1,QRSL1,DHFR2,PIEZO1,OSGEPL1,NUDT11,NAA60,GEMIN7,LZTR1,RACGAP1,PPP3CB,B4GALT4,RLF,RAPGEF6,SNRNP25,RB1,VASP,MED8,TIGAR,VMP1,PPIL2,TIMELESS,ALDH18A1,TMEM8A,PREB,ABCC1,TRAPPC9,MEMO1,KRAS,RTF1,UBE4B,NFATC2IP,ARPC1A,ZNF174,PSMC4,GOLGA4,PALB2,SYNCRIP,NIPA1,TIGD2,RNF114,FOXM1,MRPL39,XAB2,SUMO2,DUSP22,COMMD8,RPL11,CSDE1,MDM2,CORO1A,MINPP1,POC5,DVL2,GM2A,PSMA8,COQ10B,CPOX,TIGD5,SLC26A6,PRPF3,TXNL4A,RPSA,SRSF1,DNAJC10,SCAP,ZNF700,TIMM17A,TOMM6,LTA4H,AP2S1,INTS2,CTDP1,MIF4GD,CDT1,ARID5A,SUMF1,GGA2,CSNK1A1,AP3S1,RMI1,TFRC,PTPN2,IRF4,STARD9,GSTK1,NDUFV1,SLC1A4,CWC27,SLC35B4,DDX31,ABCD1,SNX2,ZMYM5,CHCHD6,CDKN2AIPNL,KPNA4,BIRC5,TFE3,SNAP29,CDCA7L,PKD2,ACADM,CHMP7,SAT2,GCSH,ZNF496,TMEM109,TAP1,NHLRC3,IKBIP,KIFC1,DBNDD1,CYB5RL,PARPBP,CDC25B,MAST2,DNMT1,NOL12,USO1,AKT2,NOL8,GNG7,ELOA,MRNIP,AURKB,MCFD2,SLC25A5,MAK16,STT3A,TMED10,PSMD8,EIF2D,ITGB1,PTPN7,UQCRH,RRS1,ARRB2,RTN3,SVIP,DDX58,PPIB,MUT,GMFG,HLA-E,NDUFA4,MAN2B1,METTL3,NDUFS4,RNF121,MEX3C,KLF16,HDAC7,DAD1,BDH1,PCYT2,GNAI2,TERF2,MORC3,NOA1,SEPT8,PKM,TOMM40,PATL1,PSMB3,ADSS,SERTAD2,SERF2,ZFP92,NSF,DCK,ERGIC3,ACLY,LPCAT4,VCPIP1,PPP6R2,PPP6R3,MAP3K5,YY1,RNF14,CDK2,ZC3HAV1,SYS1,ZBTB37,URB2,MAGED1,ADPGK,SLC25A44,AP1B1,SDHA,PHC2,CRKL,TERF2IP,MOAP1,CYHR1,ZNF75D,SHC1,UCHL5,TMBIM1,MRM2,CCT2,CDKN2AIP,HMGN4,LYRM1,CDC23,SHCBP1,AP4E1,PRDM11,VEZF1,PPP2R5A,STAT1,PPA2,TRIM32,R3HCC1L,MRI1,TCF3,BRAP,AGPAT3,MYNN,SDF2L1,SPR,RAB11A,REEP5,FOXO3,MAD2L2,PIP5K1C,RBM17,MAT2B,PTEN,CENPJ,TAGLN2,OSTC,MAP3K14,CREB1,PACS2,NCOA2,SMC4,RNASEH2C,NEK7,NET1,PARP4,TBRG4,ANAPC2,RPL27A,YIF1A,SGSH,HGS,ATP5MC3,TTLL4,MFAP1,CCDC69,BRWD3,ESYT2,SKA3,NPHP4,HNRNPAB,ST13,DNAJC24,ZNF107,KIF2C,AGFG1,SIRT2,FKBP2,USP48,UBQLN2,SNRPD3,CUTC,EDC3,UBLCP1,ZNF804A,RAP1A,THADA,EIF4A3,AP3S2,DPYSL2,AKR1B1,NDUFB9,RP2,TECR,ARID4A,TIMM50,TDP1,DPM1,FOPNL,WDR82,SLC25A22,STK17B,DHX15,CHAF1A,GEMIN5,TIMM29,COPS6,SASS6,RPS26,PSMC1,TBC1D12,TM9SF4,ZNF768,UFC1,MED13L,TIA1,MEF2A,EPHX2,PITHD1,RHBDD1,NFATC3,BANF1,ZNF335,BUD31,YBX1,KNTC1,ACAD8,UBE3C,ZNF189,ALDH9A1,KDELR1,TSTA3,CIC,OXR1,PSMA1,SEPT7,NAP1L1,NSMF,ODF2,NUP62,PITPNA,NAA20,PTDSS1,MZT2B,PDSS2,TMEM106C,IMMT,ASH1L,CHERP,WDYHV1,PLAGL2,IRF3,TWF2,ANKRD28,ANKLE1,SAR1A,APOOL,PDIA6,ACSL5,DMAC2,TOR1AIP2,GFER,RAD54B,DAP3,ZNF317,GADD45B,AKNA,REEP4,CBX4,MIF,KIF3B,GOLPH3L,CASP6,TOR3A,SRGN,DBF4,TIMM21,MFSD10,SAC3D1,CTNNBL1,YIF1B,TTC17,SLC25A1,GINS1,CSNK1G2,TELO2,ADAM17,HMGN1,NASP,ASPM,PRKAR1B,ATP5MF,SYMPK,TARS,SNRPA,MAPK3,HSPA1B,CNOT9,HLA-B,ATAD2,PLAA,ZNF330,OSBPL8,PREPL |
| 3.997e-94 | -215.06 | nuclear lumen | cellular component | GO:0031981 | 4064 | 1035 | 18223 | 2701 |
ZBTB10,TGOLN2,CCNL2,RBM4,RPL23A,USF1,RAD23B,CRY2,ECD,MOB1A,ZNRD1,RHBDD2,FTSJ3,ERCC1,GABPA,EHMT1,HNRNPF,WDHD1,NUTF2,MCM2,GINS4,SMAD2,RAD18,RPS27A,OGT,RNASEL,SMAD1,ANXA11,SMNDC1,NXT2,CLSPN,GGA1,DHX9,PDCD7,PSMD9,PARN,CDC73,TMEM179B,SMC3,RBM34,EFTUD2,GEMIN4,CPSF4,LUC7L2,SRSF11,EIF3L,AGGF1,FOXK1,MAPKAPK3,MTA2,SF3B6,GTPBP4,USP10,BCLAF1,ELK1,MAGED2,KPNA1,ETS2,WIPI2,ZNF830,TRIM41,TPX2,INO80E,DAZAP2,CPNE3,AHCTF1,ZNF420,MTA1,TBC1D14,GMEB1,NABP1,NSFL1C,INTS12,ZC3H3,RPRD1B,CGGBP1,CPNE1,POLR2L,EID1,FAM118B,KAT7,CRNKL1,E2F3,CIRBP,POLR2D,PFKFB3,GORAB,MEF2D,GSTCD,KIF2A,LSM6,NSMCE2,RNF38,SNRPG,PPP5C,USP13,SRSF6,ZFP91,TRMT6,HABP4,ABHD14B,ATG2B,IP6K2,WDR5,RRP36,SAPCD2,NEIL2,TUT4,RPA2,PSMD2,CLIC4,HUWE1,ZNF260,KANSL2,GTF2H2,MED22,DDX24,USP42,LLPH,UTP20,SH3BP5,GPS2,ACOX1,PARG,AEN,PARP10,WDR13,RBM8A,SNX15,ENSA,NENF,RUFY1,TRIM65,FANCI,PAPOLA,KRR1,FANCL,GLIS2,INTS1,SLC44A1,POP7,NOC2L,RYBP,PLK1,RPP25,PTPN18,MIOS,RBX1,RAD51AP1,SNRPB,ZBED5,PSMG1,CDC6,UBE2V1,PBRM1,EAF2,UTP3,USP21,LSG1,CHD3,GRIPAP1,ZNF367,E2F4,PRPF4,KPNA2,FAM208A,POT1,CCDC137,ZNF564,FUBP1,ZCCHC9,HJURP,PHB2,CENPF,CDK13,DNAJB1,ARID1B,SUB1,MLX,MBD2,XPA,CTR9,RBM3,ICE2,GLE1,DCAF8,LDB1,METTL22,APPL1,NPIPA1,RXRB,RPL36,SDHB,MBIP,COX7A2L,DTD1,RUVBL2,BTBD10,BCCIP,USP7,SART1,ARID2,LAGE3,PCBP1,OIP5,NRF1,PSMA6,ZNF473,BRPF3,KMT5C,PIN1,PPME1,TARDBP,TOP1MT,STRAP,SPIDR,CTDSP2,PRPF19,KDM3B,BIRC3,POLR2G,PPIE,DCLRE1C,SUGP1,AFDN,DHX16,RBL1,UHRF2,XRCC3,H3F3A,SMAD4,RAD51D,NIFK,CMAS,MCM10,C19orf53,AGO2,CDCA8,GTF3A,HMGN3,PAGR1,TUBGCP2,DNAJB9,POLR1B,ORC3,RBM15B,YTHDC1,PPAN,RPRD1A,BTAF1,PRKDC,TOP3A,RANGAP1,PCGF1,API5,DDX23,L3MBTL3,NEIL3,BBX,E2F1,RBPJ,TAF12,NR2F2,HIPK3,IFI16,MAX,H2AFZ,PNISR,CXXC1,CUL1,USP39,UBE2I,OAT,PARK7,PA2G4,NOL11,TRA2B,TAF5L,SMARCE1,CDC5L,SRSF10,NSUN2,SUPT20H,USP22,RFC2,CBFB,CLNS1A,EIF3A,PRIM1,ZMYM3,DOT1L,IWS1,MKNK1,KIF18B,BRD2,RPS14,TPP2,LUC7L3,PTPDC1,CCDC59,ZMAT3,NMD3,B4GALT2,RECQL,C9orf78,EWSR1,SCOC,POLR2K,PRKAA1,SUPT7L,VPS25,YY1AP1,NPLOC4,WDR48,C12orf10,TMEM250,EXOSC7,MSH2,TNRC18,GID8,GCC2,PRIM2,ELL2,RPS24,EXOSC9,ARID1A,FXR1,PTTG1IP,CCT8,TWISTNB,PHF6,XRCC5,EPOP,RBMX,MED15,PIAS2,ARAP1,CEBPG,APPL2,CABIN1,GPI,CYTIP,ATXN3,TP53RK,RAF1,UROD,POMP,C2orf49,DECR1,CCNA2,TAP2,TTC3,RNASEH2A,AQR,TP53BP2,ILKAP,CDK12,CFL1,SAP30,BRD4,NARF,ELP4,EDF1,PKMYT1,TRIM28,SUPT16H,RAD51C,DSN1,HINT1,DGCR8,SAFB,ATF6,BEND3,XRCC4,EYA2,PRPF4B,TKT,FAM76A,CBLL1,ARGLU1,RFWD3,CCNK,DNAJC8,PTPN11,FEM1B,CARF,CITED2,MTX2,MSH6,KAT2A,RFXANK,BMS1,KLF6,SPPL2B,CBX3,ZHX1,DUSP11,DDX5,TAF6,PURA,DEF6,DDB1,IPO4,RORB,POLA2,CCNC,LYRM4,KMT2E,COMMD5,BRIX1,SF3B2,SIVA1,JAZF1,RPF2,TCEA1,SLC35C2,CARMIL1,CARM1,SRPK2,DEAF1,LARS,SNRNP200,LAP3,VHL,RIOX2,SREK1,KMT2C,ASF1B,EIF4ENIF1,BRWD1,NIP7,U2SURP,PPM1G,SH3GLB2,CRCP,BAZ1B,STK11,CHEK2,DCAF5,UBE2D3,NSMCE4A,PPP1R12A,ZCCHC8,PM20D2,THRAP3,RGS2,QSOX2,TTF1,PRPF18,NUP205,LYAR,DTL,MED10,ZRANB1,MCPH1,POLR2I,SUGP2,SYVN1,SLTM,DAPK3,MASTL,UAP1,SIAH2,YWHAZ,CTSA,SNRNP70,C11orf1,TSEN15,TCF12,SNX27,PRKAB1,PMS2,SMARCA4,ORC1,MXD1,HNRNPA2B1,SAP130,RRN3,CD3EAP,NVL,EXOSC1,UTP4,CSTF1,UBQLN4,NXT1,SMU1,PCGF6,LSM8,ATXN1,TOLLIP,MBD3,FANCE,RPS9,ALKBH6,HNRNPR,STAT6,ARNTL,ANP32E,FKBP5,MAPK1,CWC25,DNAJC2,TRIP12,SHPRH,RAE1,PAWR,PIP4K2A,MZT2A,KLHL20,KMT5A,PPIG,NABP2,H2AFY,ANP32A,FBL,STAT3,MICAL3,PPP1R9B,DCAF6,TIMMDC1,PSPC1,HELB,MIER1,RFFL,RCOR1,PRMT2,UPF1,KMT2B,CENPT,ZMIZ1,TERF1,ADD1,MRPS15,KDM4A,XIAP,DHX8,PPP1R16B,ANKRD23,MIS12,CDK5,PSMD1,NEK6,NSRP1,SRSF4,PDS5B,NUP153,SENP1,PCBP2,MLST8,PLK3,ZNF672,AATF,TOPORS,MCL1,SMC2,BRMS1,PWWP2B,LIMK1,TFDP2,FBXL3,E2F2,AAAS,SSRP1,DDX42,PHF23,TOP2B,EZH1,LMNA,DDRGK1,DDX56,INTS7,MCM5,RTCB,ZNF326,ETV3,PRRC2A,ZMYND11,TEX10,MYBL2,RPS10,SRSF5,MPG,MATR3,ABCF1,OSBPL11,CCDC86,POLR2J,DUSP3,SETD3,SGF29,ZNF207,SARNP,FAM208B,TRERF1,IVNS1ABP,CHD1L,RMI2,WDTC1,RXYLT1,NUF2,PRKACA,SAFB2,PRKD3,CLUAP1,SP100,ATP2A2,UTP18,DUT,DDA1,NUP107,ANAPC7,FAM76B,RBM15,ATF2,RNF169,SHOC2,PSRC1,INTS13,RNPS1,WBP2,ATP6V0A1,NUSAP1,CDCA2,DDX17,TAF2,CDC16,HIPK2,FUS,PDXK,ZBTB11,GEN1,COIL,RPS2,GMCL1,JMJD6,AKT1S1,ETS1,PNO1,FBXO3,KRI1,ADD3,SUV39H2,PPP1R8,PRDM4,GEMIN6,GTSE1,HNRNPM,NUDC,PDPK1,PPP3CA,POLK,DDX39A,RPA1,KEAP1,POLE,TATDN2,MAPK6,PITX1,PML,LRPPRC,HMGB2,USF2,ANAPC4,DDX47,THOC1,CSNK2A1,EBNA1BP2,GIT2,LIN9,PCNA,ZNF639,XRCC2,TRMU,ETV6,ZFYVE27,MCMBP,CCAR1,SP3,METTL1,EXOSC6,BAZ2A,EZR,BRCA1,PRKRA,ANLN,OPTN,TIMM13,CDCA4,TONSL,ACTB,ZNF45,SINHCAF,GEMIN7,TMUB1,CTCF,RACGAP1,PPP3CB,ASXL2,RB1,SNRNP25,MED8,VMP1,PPIL2,TIMELESS,AFF1,MDFIC,MAML1,NQO2,UTP15,RTF1,ZNF174,PSMC4,CDC27,PALB2,SYNCRIP,SNAP23,TBPL1,PRMT7,FOXM1,XAB2,COPE,SUMO2,HCFC1R1,RPAIN,COMMD8,RPL11,RAD23A,PDK2,ZBTB21,MDM2,TNFAIP8,SAP30L,DVL2,POC5,RPL35,DNAJC9,NFATC2,PRPF3,KDM1B,TXNL4A,USP36,RPSA,SRSF1,CLK3,TIMM17A,PSMD3,MAFK,ZNF436,NCOA1,LTA4H,ZNF146,INTS2,CTDP1,CDC40,MIF4GD,CDT1,ARID5A,SMC6,NKRF,CSNK1A1,RMI1,WRNIP1,PTPN2,IRF4,CWC27,SS18L1,DDX31,PTGES3,CENPM,CAMK2G,ZMYM5,PPWD1,FAM50B,KPNA4,CDKN2AIPNL,BIRC5,TFE3,SNAP29,CDCA7L,ACADM,UBE2C,ZNF496,NDUFB6,CCNB1,POLR3K,UTP25,CYB5RL,PARPBP,CDC25B,DNMT1,NOL12,USO1,AKT2,NOL8,MKI67,ELOA,DDX20,MRNIP,AURKB,MAK16,PSMD8,EIF2D,WDR4,PTPN7,RRS1,HDAC2,HSPH1,CHTF18,KIF23,NOTCH2,PMF1,METTL3,JMY,HDAC7,BDH1,GNAI2,EEF1D,MORC3,TERF2,DDX28,PHF10,KDM3A,SF3A2,PATL1,PSMB3,FAS,SERTAD2,PPP3R1,DCAF11,ACLY,TCOF1,PPP6R3,YY1,CDK2,NRBP1,DNMT3A,TRIP10,URB2,SUZ12,SF3B1,RPS6KA1,OLA1,SDHA,CRKL,PHC2,TERF2IP,CYHR1,KDM2A,UCHL5,TNPO2,CDKN1B,TALDO1,GPX4,MRM2,CDKN2AIP,RFC3,ERF,LYRM1,CUL3,SLBP,CDC23,GAR1,H2AFV,PSMB9,CENPU,NSA2,VEZF1,FAAP100,TBL3,STAT1,H2AFX,PDCD11,ATMIN,CSNK1D,POLQ,NCOR2,BABAM1,MRI1,TCF3,BLM,SPR,FOXO3,MAD2L2,GTF2F1,PIP5K1C,RBM17,PTEN,CENPJ,COPS7B,CREB1,MAP3K14,UBE2M,NCOA2,SMC4,ZFP64,NEK7,DENND1B,WDR18,ILF3,ANAPC2,MARK2,POLR2A,HNRNPH3,TFDP1,KHSRP,NAXE,ASNA1,BYSL,DDX52,S100PBP,IER2,HNRNPAB,NOP2,NF1,UBN1,ALKBH5,UBE2Z,SIRT2,TAF6L,USP48,SNRPD3,MAPK14,CUTC,SNAPC4,MBD4,UBLCP1,EIF4A3,IMPAD1,METTL14,SRI,AKR1B1,KIF22,NFU1,RP2,OGG1,ARID4A,TIMM50,ELOF1,FYTTD1,COPS8,TRIM8,WDR82,SOX4,DHX15,CHAF1A,UBTF,GEMIN5,PAF1,SPATA2,PQBP1,ATXN2L,COPS6,RPS26,PSMC1,RPS15,AGTRAP,ZNF768,CIB1,TIA1,MED13L,MEF2A,SRRT,NFATC3,BANF1,ZNF335,BUD31,YBX1,BCL2,KIFAP3,HP1BP3,CIC,OXR1,PSMA1,ISG15,CAND1,RBM25,NSMF,CDCA5,RBBP4,HNRNPDL,MZT2B,SMARCD1,MBD1,ASH1L,MPHOSPH8,CHERP,HNRNPUL2,NSD3,IRF3,CHD1,MEAF6,ANKRD28,BABAM2,AKAP8,CHTOP,RLIM,ACSL5,ZNF500,PSMB7,ERBIN,NDUFB1,DAP3,TAB2,CHCHD1,TULP3,AKNA,USP11,SMURF1,CBX4,MIF,CASP6,EYA1,DBF4,MRPS26,LETMD1,FBXO5,CTNNBL1,BRD7,GINS1,GTF3C6,TELO2,HMGN1,NASP,POLR3GL,MEN1,SYMPK,SNRPA,HSPA1B,MAPK3,ATAD2,ZNF330,ZRANB2,SRSF3,MBD6,TATDN1 |
| 3.439e-93 | -212.91 | nucleoplasm | cellular component | GO:0005654 | 3463 | 923 | 18223 | 2701 |
ZBTB10,ADD1,KDM4A,XIAP,DHX8,TGOLN2,CCNL2,PPP1R16B,ANKRD23,RBM4,CDK5,USF1,PSMD1,NEK6,NSRP1,RAD23B,SRSF4,PDS5B,CRY2,NUP153,ECD,ZNRD1,RHBDD2,SENP1,PCBP2,MLST8,PLK3,ZNF672,ERCC1,GABPA,EHMT1,HNRNPF,WDHD1,MCL1,TOPORS,SMC2,NUTF2,MCM2,GINS4,BRMS1,PWWP2B,SMAD2,RAD18,RPS27A,LIMK1,OGT,FBXL3,TFDP2,SMAD1,E2F2,AAAS,ANXA11,SMNDC1,DDX42,NXT2,SSRP1,CLSPN,GGA1,PHF23,DHX9,TOP2B,EZH1,PDCD7,PSMD9,CDC73,LMNA,TMEM179B,SMC3,INTS7,MCM5,EFTUD2,ZNF326,RTCB,GEMIN4,CPSF4,LUC7L2,SRSF11,EIF3L,AGGF1,ETV3,FOXK1,PRRC2A,MAPKAPK3,ZMYND11,MTA2,SF3B6,TEX10,RPS10,MYBL2,USP10,BCLAF1,SRSF5,MPG,ELK1,ABCF1,OSBPL11,KPNA1,POLR2J,ETS2,DUSP3,SETD3,WIPI2,ZNF830,SGF29,ZNF207,TRIM41,FAM208B,SARNP,TRERF1,IVNS1ABP,CHD1L,WDTC1,RMI2,TPX2,RXYLT1,INO80E,DAZAP2,PRKACA,SAFB2,CLUAP1,PRKD3,AHCTF1,ZNF420,ATP2A2,SP100,UTP18,MTA1,TBC1D14,DUT,DDA1,GMEB1,NABP1,NSFL1C,INTS12,ANAPC7,FAM76B,ATF2,RBM15,ZC3H3,RPRD1B,CGGBP1,RNF169,CPNE1,SHOC2,PSRC1,POLR2L,EID1,FAM118B,KAT7,INTS13,CRNKL1,POLR2D,RNPS1,CIRBP,E2F3,ATP6V0A1,PFKFB3,CDCA2,GORAB,MEF2D,GSTCD,DDX17,TAF2,KIF2A,CDC16,LSM6,NSMCE2,HIPK2,RNF38,PDXK,FUS,SNRPG,PPP5C,GEN1,ZBTB11,COIL,USP13,RPS2,SRSF6,TRMT6,HABP4,JMJD6,ATG2B,AKT1S1,IP6K2,WDR5,ETS1,RRP36,PNO1,NEIL2,FBXO3,RPA2,PSMD2,ADD3,SUV39H2,HUWE1,PPP1R8,PRDM4,ZNF260,GTSE1,GEMIN6,KANSL2,GTF2H2,HNRNPM,MED22,NUDC,PDPK1,PPP3CA,POLK,USP42,DDX39A,RPA1,UTP20,SH3BP5,KEAP1,POLE,GPS2,TATDN2,PARG,ACOX1,MAPK6,LRPPRC,PML,AEN,HMGB2,USF2,ANAPC4,DDX47,THOC1,WDR13,RBM8A,ENSA,CSNK2A1,NENF,RUFY1,GIT2,TRIM65,FANCI,PAPOLA,KRR1,LIN9,FANCL,PCNA,GLIS2,ZNF639,INTS1,TRMU,SLC44A1,XRCC2,POP7,NOC2L,ZFYVE27,MCMBP,CCAR1,RYBP,PLK1,SP3,METTL1,RPP25,EXOSC6,PTPN18,MIOS,RBX1,BAZ2A,RAD51AP1,SNRPB,ZBED5,PSMG1,CDC6,UBE2V1,PBRM1,EAF2,UTP3,BRCA1,ANLN,PRKRA,USP21,LSG1,OPTN,CDCA4,TONSL,CHD3,GRIPAP1,ZNF367,E2F4,PRPF4,KPNA2,ACTB,ZNF45,FAM208A,SINHCAF,POT1,GEMIN7,ZNF564,FUBP1,TMUB1,HJURP,CENPF,CTCF,RACGAP1,CDK13,DNAJB1,PPP3CB,ASXL2,ARID1B,SNRNP25,RB1,MLX,MED8,MBD2,XPA,PPIL2,CTR9,TIMELESS,RBM3,AFF1,ICE2,MAML1,DCAF8,NQO2,LDB1,UTP15,RTF1,METTL22,APPL1,NPIPA1,ZNF174,PSMC4,RXRB,SDHB,MBIP,PALB2,SYNCRIP,CDC27,SNAP23,TBPL1,PRMT7,RUVBL2,BCCIP,USP7,SART1,ARID2,FOXM1,XAB2,SUMO2,COPE,LAGE3,HCFC1R1,PCBP1,COMMD8,RPAIN,RAD23A,RPL11,OIP5,ZBTB21,PDK2,NRF1,PSMA6,ZNF473,MDM2,TNFAIP8,KMT5C,BRPF3,PIN1,PPME1,TARDBP,STRAP,SAP30L,SPIDR,CTDSP2,POC5,DVL2,PRPF19,KDM3B,BIRC3,POLR2G,PPIE,DNAJC9,NFATC2,DCLRE1C,PRPF3,KDM1B,TXNL4A,RPSA,USP36,SRSF1,SUGP1,AFDN,DHX16,RBL1,CLK3,MAFK,PSMD3,TIMM17A,ZNF436,UHRF2,XRCC3,NCOA1,H3F3A,LTA4H,SMAD4,RAD51D,INTS2,CTDP1,NIFK,CMAS,MCM10,CDC40,CDT1,AGO2,CDCA8,ARID5A,SMC6,GTF3A,HMGN3,CSNK1A1,PAGR1,RMI1,TUBGCP2,PTPN2,IRF4,CWC27,SS18L1,CENPM,PTGES3,POLR1B,ORC3,CAMK2G,RBM15B,YTHDC1,RPRD1A,BTAF1,PRKDC,ZMYM5,TOP3A,RANGAP1,FAM50B,PPWD1,PCGF1,API5,DDX23,CDKN2AIPNL,KPNA4,BIRC5,SNAP29,NEIL3,TFE3,BBX,E2F1,RBPJ,TAF12,ACADM,NR2F2,UBE2C,HIPK3,IFI16,ZNF496,MAX,PNISR,NDUFB6,CXXC1,CUL1,USP39,CCNB1,UBE2I,OAT,POLR3K,PARK7,UTP25,NOL11,CYB5RL,PARPBP,TRA2B,TAF5L,CDC25B,SMARCE1,DNMT1,CDC5L,SRSF10,AKT2,NSUN2,ELOA,MKI67,MRNIP,DDX20,SUPT20H,AURKB,USP22,CBFB,RFC2,CLNS1A,PRIM1,ZMYM3,IWS1,DOT1L,MKNK1,KIF18B,BRD2,PSMD8,RPS14,TPP2,LUC7L3,WDR4,EIF2D,PTPN7,PTPDC1,CCDC59,ZMAT3,NMD3,HDAC2,B4GALT2,HSPH1,C9orf78,RECQL,SCOC,POLR2K,CHTF18,PRKAA1,KIF23,PMF1,NOTCH2,SUPT7L,METTL3,VPS25,YY1AP1,NPLOC4,JMY,WDR48,C12orf10,TMEM250,EXOSC7,HDAC7,BDH1,MSH2,GNAI2,TNRC18,TERF2,MORC3,GID8,GCC2,PRIM2,ELL2,RPS24,EXOSC9,ARID1A,PTTG1IP,KDM3A,PATL1,SF3A2,CCT8,PSMB3,TWISTNB,PHF6,FAS,XRCC5,SERTAD2,EPOP,RBMX,MED15,ACLY,DCAF11,ARAP1,CEBPG,APPL2,PPP3R1,PIAS2,CABIN1,GPI,YY1,PPP6R3,CDK2,NRBP1,CYTIP,DNMT3A,ATXN3,TP53RK,TRIP10,RPS6KA1,SF3B1,RAF1,SUZ12,UROD,POMP,C2orf49,PHC2,TERF2IP,CRKL,DECR1,CYHR1,CCNA2,KDM2A,UCHL5,CDKN1B,TAP2,RNASEH2A,TP53BP2,AQR,TALDO1,ILKAP,CDK12,GPX4,SAP30,CDKN2AIP,BRD4,RFC3,ERF,LYRM1,CUL3,SLBP,ELP4,EDF1,PKMYT1,CDC23,PSMB9,GAR1,TRIM28,CENPU,SUPT16H,VEZF1,RAD51C,DSN1,HINT1,DGCR8,SAFB,TBL3,FAAP100,H2AFX,STAT1,ATF6,BEND3,PDCD11,XRCC4,EYA2,ATMIN,CSNK1D,POLQ,PRPF4B,NCOR2,MRI1,TCF3,BABAM1,TKT,FAM76A,CBLL1,ARGLU1,BLM,SPR,FOXO3,MAD2L2,PIP5K1C,GTF2F1,RBM17,RFWD3,CCNK,DNAJC8,PTEN,CENPJ,PTPN11,FEM1B,COPS7B,CARF,CITED2,CREB1,UBE2M,MSH6,NCOA2,SMC4,ZFP64,KAT2A,DENND1B,NEK7,WDR18,ILF3,RFXANK,BMS1,ANAPC2,MARK2,SPPL2B,POLR2A,CBX3,ZHX1,HNRNPH3,TFDP1,NAXE,KHSRP,DDX5,DUSP11,TAF6,DEF6,DDB1,BYSL,DDX52,S100PBP,RORB,POLA2,CCNC,IER2,LYRM4,NOP2,HNRNPAB,UBN1,KMT2E,ALKBH5,UBE2Z,TAF6L,SIRT2,SNRPD3,USP48,COMMD5,MAPK14,SNAPC4,CUTC,SF3B2,MBD4,EIF4A3,SIVA1,METTL14,IMPAD1,SRI,AKR1B1,KIF22,RP2,NFU1,TCEA1,SLC35C2,OGG1,CARMIL1,ARID4A,CARM1,TIMM50,ELOF1,SRPK2,COPS8,FYTTD1,LARS,SNRNP200,TRIM8,LAP3,VHL,RIOX2,SREK1,WDR82,SOX4,KMT2C,ASF1B,DHX15,PAF1,GEMIN5,UBTF,EIF4ENIF1,BRWD1,PPM1G,U2SURP,PQBP1,ATXN2L,SH3GLB2,CRCP,BAZ1B,STK11,CHEK2,COPS6,RPS26,PSMC1,DCAF5,UBE2D3,RPS15,NSMCE4A,PPP1R12A,AGTRAP,ZCCHC8,ZNF768,CIB1,TIA1,MED13L,MEF2A,PM20D2,THRAP3,QSOX2,TTF1,SRRT,PRPF18,DTL,NFATC3,MED10,BANF1,ZNF335,BUD31,BCL2,YBX1,ZRANB1,MCPH1,HP1BP3,POLR2I,CIC,OXR1,SUGP2,PSMA1,SYVN1,SLTM,DAPK3,ISG15,CAND1,MASTL,RBM25,UAP1,NSMF,CDCA5,SIAH2,YWHAZ,CTSA,RBBP4,SNRNP70,C11orf1,HNRNPDL,MZT2B,TSEN15,SMARCD1,TCF12,MBD1,SNX27,PRKAB1,ASH1L,CHERP,HNRNPUL2,PMS2,SMARCA4,NSD3,IRF3,ORC1,MEAF6,MXD1,HNRNPA2B1,ANKRD28,SAP130,RRN3,BABAM2,CD3EAP,NVL,EXOSC1,AKAP8,CHTOP,UTP4,RLIM,CSTF1,NXT1,ZNF500,SMU1,PCGF6,PSMB7,LSM8,ATXN1,ERBIN,NDUFB1,MBD3,FANCE,TOLLIP,RPS9,ALKBH6,DAP3,TAB2,HNRNPR,STAT6,CHCHD1,ARNTL,FKBP5,USP11,AKNA,SMURF1,MAPK1,CBX4,CWC25,MIF,DNAJC2,TRIP12,CASP6,SHPRH,EYA1,MRPS26,DBF4,LETMD1,PIP4K2A,FBXO5,MZT2A,KLHL20,CTNNBL1,KMT5A,PPIG,NABP2,H2AFY,BRD7,ANP32A,FBL,STAT3,MICAL3,GINS1,TELO2,GTF3C6,PPP1R9B,DCAF6,HMGN1,NASP,TIMMDC1,PSPC1,MIER1,RFFL,RCOR1,POLR3GL,PRMT2,MEN1,SYMPK,SNRPA,MAPK3,HSPA1B,UPF1,ATAD2,KMT2B,ZRANB2,SRSF3,MBD6,CENPT,TATDN1,ZMIZ1,TERF1 |
| 3.610e-93 | -212.86 | intracellular organelle lumen | cellular component | GO:0070013 | 5182 | 1227 | 18223 | 2701 |
ZBTB10,HEXB,TGOLN2,LACTB2,CCNL2,RBM4,RPL23A,USF1,RAD23B,MECR,CRY2,ECD,MOB1A,ZNRD1,LRRC59,RHBDD2,FTSJ3,MRPL57,ERCC1,GABPA,EHMT1,HNRNPF,WDHD1,NUTF2,COA7,MCM2,GINS4,SMAD2,RAD18,RPS27A,OGT,RNASEL,SMAD1,ANXA11,SMNDC1,NXT2,CLSPN,GGA1,DHX9,PDCD7,PSMD9,PARN,CDC73,TMEM179B,SMC3,RBM34,EFTUD2,GEMIN4,MYDGF,MRPL21,CPSF4,MVP,NSUN4,LUC7L2,SRSF11,EIF3L,AGGF1,FOXK1,MAPKAPK3,MTA2,SF3B6,ERO1A,GTPBP4,USP10,BCLAF1,MRPL16,ELK1,MAGED2,KPNA1,TXNDC16,ETS2,WIPI2,ZNF830,ACSF2,MRPL3,TRIM41,KARS,TPX2,INO80E,DAZAP2,CPNE3,AHCTF1,ZNF420,MTA1,TBC1D14,GMEB1,NABP1,NSFL1C,MICU2,INTS12,ZC3H3,RPRD1B,CGGBP1,CPNE1,POLR2L,EID1,FAM118B,KAT7,IDH3A,CRNKL1,E2F3,CIRBP,POLR2D,PFKFB3,GORAB,MEF2D,GSTCD,KIF2A,LSM6,NSMCE2,RNF38,SNRPG,PPP5C,PITRM1,TUBB,USP13,SRSF6,ZFP91,TRMT6,HABP4,ABHD14B,ATG2B,IP6K2,ATP5F1B,WDR5,RRP36,SAPCD2,NEIL2,TUT4,GOLM1,RPA2,PSMD2,CLIC4,HUWE1,ZNF260,KANSL2,GTF2H2,MED22,SPTAN1,DDX24,USP42,HEBP2,LLPH,UTP20,SH3BP5,GPS2,PARG,ACOX1,DBI,FAM3C,AEN,PARP10,WDR13,RBM8A,SNX15,ENSA,NENF,RUFY1,TRIM65,FANCI,PAPOLA,KRR1,FANCL,GLIS2,TIMM23,INTS1,SLC44A1,POP7,NOC2L,RYBP,PLK1,RPP25,PTPN18,MIOS,RBX1,RAD51AP1,SNRPB,ZBED5,PSMG1,CDC6,UBE2V1,PBRM1,EAF2,UTP3,USP21,LSG1,CHD3,GRIPAP1,ZNF367,E2F4,PRPF4,KPNA2,FAM208A,POT1,CCDC137,ZNF564,FUBP1,ZCCHC9,HJURP,PHB2,CENPF,SDC2,CHCHD2,CDK13,DNAJB1,ARID1B,SUB1,MLX,MBD2,XPA,CTR9,RBM3,ICE2,GLE1,MRPL48,DCAF8,LDB1,METTL22,ARMC8,APPL1,NPIPA1,RXRB,RPL36,SDHB,MBIP,COX7A2L,SIL1,DTD1,RUVBL2,BTBD10,BCCIP,USP7,SART1,SUCLG1,ARID2,LAGE3,LYN,PCBP1,OIP5,MRPL50,NRF1,PSMA6,ZNF473,KMT5C,BRPF3,PIN1,PPME1,TARDBP,TOP1MT,STRAP,SPIDR,CTDSP2,PRPF19,PPIF,KDM3B,BIRC3,POLR2G,PPT1,PPIE,DCLRE1C,VDAC1,MRPS14,SUGP1,AFDN,IDE,DHX16,RBL1,FASTK,UHRF2,XRCC3,H3F3A,CHID1,SMAD4,RAD51D,NIFK,CMAS,C19orf53,MCM10,MTERF1,PDAP1,AGO2,CDCA8,GTF3A,HMGN3,PAGR1,TUBGCP2,DNAJB9,CTSS,POLR1B,ORC3,RBM15B,YTHDC1,PPAN,ACP2,RPRD1A,BTAF1,PRKDC,TUFM,TOP3A,RANGAP1,PCGF1,HAGH,API5,DDX23,L3MBTL3,NEIL3,BBX,E2F1,IMPDH1,RBPJ,TAF12,NR2F2,PGAM1,HIPK3,IFI16,MAX,H2AFZ,PNISR,ADAM10,PRKCSH,CXXC1,CUL1,USP39,GYG1,UBE2I,OAT,PARK7,PA2G4,NOL11,TRA2B,SUCLG2,TAF5L,SMARCE1,CDC5L,SRSF10,NSUN2,SUPT20H,USP22,CBFB,RFC2,CLNS1A,EIF3A,PRIM1,ZMYM3,DOT1L,IWS1,MKNK1,KIF18B,BRD2,RPS14,TPP2,LUC7L3,MRPL27,PTPDC1,CCDC59,ZMAT3,NMD3,B4GALT2,RECQL,C9orf78,EWSR1,SCOC,POLR2K,PRKAA1,CYCS,SUPT7L,VPS25,NDUFS7,YY1AP1,NPLOC4,WDR48,C12orf10,TMEM250,EXOSC7,ARPC5,MSH2,OSTF1,MRPL40,TNRC18,MRM3,APOL1,GID8,GCC2,PRIM2,ELL2,C1orf35,RPS24,EXOSC9,ARID1A,FXR1,PTTG1IP,CCT8,TWISTNB,PHF6,XRCC5,CAT,MTHFD2,EPOP,RBMX,MED15,PIAS2,ARAP1,CEBPG,APPL2,CABIN1,GPI,CYTIP,ATXN3,TP53RK,RAF1,UROD,POMP,BCL2L1,C2orf49,NUDT19,DECR1,CCNA2,MRPS27,TAP2,TTC3,RNASEH2A,AQR,TP53BP2,ILKAP,CDK12,CFL1,SAP30,BRD4,NARF,VDAC2,ELP4,EDF1,PKMYT1,TRIM28,SUPT16H,RAD51C,DSN1,HINT1,DGCR8,SAFB,ATF6,BEND3,XRCC4,EYA2,PRPF4B,NDUFS1,MANBA,TKT,FAM76A,CBLL1,ARGLU1,RFWD3,CCNK,DNAJC8,PTPN11,MRPL54,FEM1B,CARF,CNN2,CITED2,MTX2,MSH6,KAT2A,RFXANK,BMS1,ARSK,KLF6,SPPL2B,CBX3,ZHX1,DUSP11,DDX5,NDUFS5,TAF6,PURA,DEF6,DDB1,IPO4,RORB,POLA2,CCNC,LYRM4,KMT2E,COMMD5,BRIX1,MRPL19,SF3B2,PCYOX1L,GOT2,SIVA1,JAZF1,HADHB,RPF2,TCEA1,SLC35C2,CARMIL1,CARM1,SRPK2,DEAF1,LARS,SNRNP200,LAP3,VHL,RIOX2,SREK1,SUMF2,KMT2C,ASF1B,EIF4ENIF1,BRWD1,NIP7,U2SURP,PPM1G,SH3GLB2,CRCP,CAB39,BAZ1B,STK11,CHEK2,CLU,MRPL13,DCAF5,CAPN1,UBE2D3,NSMCE4A,PPP1R12A,ZCCHC8,PM20D2,THRAP3,RGS2,QSOX2,TTF1,NUP205,PRPF18,LYAR,DTL,MED10,ZRANB1,MCPH1,POLR2I,CREG1,SUGP2,GBA,SYVN1,SLTM,DAPK3,MASTL,UAP1,SIAH2,YWHAZ,CTSA,SNRNP70,C11orf1,TSEN15,TCF12,SNX27,PRKAB1,MDH2,PMS2,SMARCA4,ORC1,MXD1,HNRNPA2B1,SAP130,RRN3,CD3EAP,NVL,EXOSC1,CS,UTP4,CSTF1,UBQLN4,NXT1,SMU1,PCGF6,ATXN1,LSM8,OGDH,EDEM2,TOLLIP,MBD3,FANCE,RPS9,PDHX,ALKBH6,HNRNPR,STAT6,ARNTL,ANP32E,FKBP5,MAPK1,CWC25,DNAJC2,TRIP12,SHPRH,RAE1,PAWR,PIP4K2A,GFM2,FERMT3,MZT2A,KLHL20,KMT5A,PPIG,NABP2,H2AFY,ANP32A,NDUFS8,FBL,STAT3,MICAL3,TGFB1,PPP1R9B,DCAF6,FAM49B,TIMMDC1,HELB,PSPC1,MIER1,NADK2,RFFL,RCOR1,PRMT2,CTSL,UPF1,KMT2B,ACAT1,CENPT,ZMIZ1,TERF1,ADD1,MRPS15,KDM4A,XIAP,DHX8,GLUD1,PPP1R16B,ANKRD23,MIS12,CDK5,PSMD1,NEK6,NSRP1,SRSF4,PDS5B,NUP153,SENP1,PCBP2,MLST8,PLK3,ZNF672,AATF,MRPL43,MCL1,TOPORS,SMC2,STOML2,BRMS1,PWWP2B,LIMK1,PRDX5,MLYCD,FBXL3,TFDP2,E2F2,LONP2,AAAS,SSRP1,DDX42,MRPL9,MRPS2,PHF23,TOP2B,EZH1,LMNA,DDRGK1,GNS,DDX56,INTS7,MCM5,RTCB,ZNF326,CARS2,CYFIP1,TIMM8B,ETV3,PRRC2A,ZMYND11,TEX10,MYBL2,RPS10,SRSF5,MPG,MATR3,ABCF1,SCARB2,OSBPL11,CCDC86,POLR2J,DUSP3,SETD3,HEXA,SGF29,ZNF207,FAM208B,SARNP,TRERF1,IVNS1ABP,CHD1L,RMI2,WDTC1,NIT2,NUF2,RXYLT1,SAFB2,PRKACA,APP,KTN1,PRKD3,CLUAP1,SP100,ATP2A2,UTP18,DUT,GRSF1,DDA1,NUP107,ANAPC7,FAM76B,CLN6,RBM15,ATF2,RNF169,SHOC2,PSRC1,INTS13,RNPS1,WBP2,ATP6V0A1,NUSAP1,CDCA2,NDUFA7,DDX17,TAF2,CDC16,HIPK2,FUS,PDXK,ZBTB11,GEN1,COIL,RPS2,JMJD6,GMCL1,AKT1S1,ETS1,PNO1,KRI1,FBXO3,ADD3,SUV39H2,PPP1R8,PRDM4,GEMIN6,GTSE1,HNRNPM,NUDC,PDPK1,PPP3CA,POLK,GALC,MRPS10,DDX39A,RPA1,KEAP1,POLE,TATDN2,WNT5B,PITX1,MAPK6,PML,LRPPRC,HMGB2,PSAP,USF2,ANAPC4,DDX47,AGRN,THOC1,MCCC1,CSNK2A1,EBNA1BP2,KCMF1,GIT2,LIN9,PCNA,ZNF639,ETV6,TRMU,XRCC2,ZFYVE27,MCMBP,CCAR1,MRPL32,SP3,METTL1,EXOSC6,BAZ2A,MRPL12,EZR,BRCA1,PRKRA,ANLN,OPTN,TIMM13,CDCA4,TONSL,NAGLU,ACTB,DHFR2,ZNF45,SINHCAF,GEMIN7,TMUB1,ASAH1,CTCF,RACGAP1,PPP3CB,ASXL2,SNRNP25,RB1,MED8,VMP1,PPIL2,TIMELESS,AFF1,MDFIC,MAML1,NQO2,UTP15,RTF1,ZNF174,PSMC4,PALB2,SYNCRIP,CDC27,SNAP23,TBPL1,PRMT7,ATP5F1A,FOXM1,XAB2,MRPL39,SUMO2,COPE,HCFC1R1,RPAIN,COMMD8,RPL11,RAD23A,PDK2,ZBTB21,MDM2,TNFAIP8,MRPL34,MINPP1,SAP30L,GM2A,DVL2,POC5,RPL35,TIMP2,CPOX,DNAJC9,NFATC2,PRPF3,KDM1B,TXNL4A,USP36,RPSA,SRSF1,DNAJC10,MRPL2,CLK3,TIMM17A,PSMD3,MAFK,ZNF436,NCOA1,LTA4H,ZNF146,INTS2,CTDP1,GOLIM4,CDC40,MIF4GD,CDT1,ARID5A,SMC6,NKRF,SUMF1,CSNK1A1,RMI1,WRNIP1,PTPN2,IRF4,GSTK1,CWC27,SS18L1,DDX31,PTGES3,CENPM,CAMK2G,ZMYM5,PPWD1,FAM50B,NEU1,CDKN2AIPNL,KPNA4,GOLGA7,BIRC5,TFE3,SNAP29,CDCA7L,ACADM,UBE2C,GCSH,ZNF496,NDUFB6,NHLRC3,CCNB1,POLR3K,UTP25,CYB5RL,PARPBP,CDC25B,DNMT1,NOL12,USO1,AKT2,ARHGAP45,NOL8,MKI67,ELOA,MRNIP,DDX20,AURKB,SLC25A5,MAK16,PSMD8,WDR4,EIF2D,PTPN7,DHTKD1,RRS1,HDAC2,PPIB,HSPH1,MUT,GMFG,CHTF18,KIF23,MAN2B1,NOTCH2,PMF1,METTL3,JMY,HDAC7,BDH1,GNAI2,EEF1D,MORC3,TERF2,FTL,PHF10,DDX28,PKM,KDM3A,PATL1,SF3A2,PSMB3,FAS,SERTAD2,QARS,ACLY,PPP3R1,DCAF11,VCPIP1,TCOF1,PPP6R3,YY1,CDK2,NRBP1,DNMT3A,TRIP10,RPS6KA1,SUZ12,SF3B1,URB2,OLA1,SDHA,TERF2IP,PHC2,FLAD1,CRKL,APLP2,CYHR1,KDM2A,SHC1,UCHL5,CDKN1B,TNPO2,TALDO1,GPX4,MRM2,CDKN2AIP,CCT2,RFC3,ERF,LYRM1,CUL3,SLBP,CDC23,POLG2,GAR1,H2AFV,AP4E1,PSMB9,CENPU,NSA2,VEZF1,MRPL55,TBL3,FAAP100,STAT1,PPA2,H2AFX,PDCD11,CSNK1D,ATMIN,POLQ,NCOR2,TWNK,MRI1,TCF3,BABAM1,SDF2L1,BLM,SPR,FOXO3,MAD2L2,PIP5K1C,GTF2F1,RBM17,PTEN,CENPJ,CRAT,COPS7B,CREB1,MAP3K14,CNPY3,UBE2M,NCOA2,SMC4,ZFP64,DENND1B,NEK7,WDR18,ILF3,TBRG4,ANAPC2,MARK2,POLR2A,NUCB1,SGSH,PRDX3,HNRNPH3,TFDP1,KHSRP,NAXE,ASNA1,BYSL,S100PBP,DDX52,ADA2,IER2,NOP2,HNRNPAB,UBN1,NF1,ALKBH5,UBE2Z,SIRT2,TAF6L,SNRPD3,USP48,MAPK14,SNAPC4,CUTC,BCAT2,MBD4,UBLCP1,EIF4A3,IMPAD1,METTL14,SRI,AKR1B1,KIF22,RP2,NFU1,OGG1,ARID4A,TIMM50,ELOF1,COPS8,FYTTD1,TRIM8,WDR82,SOX4,DHX15,CHAF1A,UBTF,GEMIN5,PAF1,SPATA2,TIMM29,IARS2,PQBP1,ATXN2L,ROCK1,COPS6,RPS26,PSMC1,RPS15,AGTRAP,ZNF768,CIB1,MED13L,TIA1,MEF2A,SRRT,NFATC3,BANF1,ZNF335,BUD31,BCL2,KIFAP3,YBX1,ACAD8,HP1BP3,CIC,OXR1,PSMA1,ISG15,CAND1,RBM25,NSMF,CDCA5,RBBP4,HNRNPDL,MZT2B,PDSS2,SMARCD1,MBD1,ASH1L,MPHOSPH8,CHERP,HNRNPUL2,NSD3,IRF3,CHD1,MEAF6,ANKRD28,BABAM2,AKAP8,CHTOP,APOOL,PDIA6,HTRA2,RLIM,ACSL5,ZNF500,PSMB7,NLN,ERBIN,NDUFB1,GFER,DAP3,TAB2,CHCHD1,TULP3,CANT1,USP11,AKNA,SMURF1,CBX4,MIF,MRPL42,CASP6,EYA1,TOR3A,SRGN,MRPS26,DBF4,LETMD1,FBXO5,CTNNBL1,BRD7,MRPL11,GINS1,TELO2,GTF3C6,HMGN1,NASP,POLR3GL,MEN1,SYMPK,SNRPA,HSPA1B,MAPK3,ATAD2,ZNF330,ZRANB2,MBD6,SRSF3,IDH3B,TATDN1 |
| 3.610e-93 | -212.86 | organelle lumen | cellular component | GO:0043233 | 5182 | 1227 | 18223 | 2701 |
ZBTB10,HEXB,TGOLN2,LACTB2,CCNL2,RBM4,RPL23A,USF1,RAD23B,MECR,CRY2,ECD,MOB1A,LRRC59,ZNRD1,RHBDD2,FTSJ3,MRPL57,ERCC1,GABPA,EHMT1,HNRNPF,WDHD1,NUTF2,MCM2,COA7,GINS4,SMAD2,RAD18,RPS27A,OGT,RNASEL,SMAD1,ANXA11,SMNDC1,NXT2,CLSPN,GGA1,DHX9,PDCD7,PSMD9,PARN,CDC73,TMEM179B,SMC3,RBM34,EFTUD2,GEMIN4,MYDGF,MRPL21,CPSF4,MVP,NSUN4,LUC7L2,SRSF11,EIF3L,AGGF1,FOXK1,MAPKAPK3,MTA2,SF3B6,ERO1A,GTPBP4,USP10,BCLAF1,MRPL16,ELK1,MAGED2,KPNA1,TXNDC16,ETS2,WIPI2,ZNF830,ACSF2,MRPL3,KARS,TRIM41,TPX2,INO80E,DAZAP2,CPNE3,ZNF420,AHCTF1,MTA1,TBC1D14,GMEB1,NSFL1C,NABP1,MICU2,INTS12,ZC3H3,RPRD1B,CGGBP1,CPNE1,POLR2L,EID1,FAM118B,KAT7,IDH3A,CRNKL1,CIRBP,POLR2D,E2F3,PFKFB3,GORAB,MEF2D,GSTCD,KIF2A,LSM6,NSMCE2,RNF38,SNRPG,PPP5C,PITRM1,TUBB,USP13,SRSF6,ZFP91,HABP4,TRMT6,ATG2B,ABHD14B,ATP5F1B,IP6K2,WDR5,RRP36,SAPCD2,TUT4,NEIL2,GOLM1,RPA2,PSMD2,CLIC4,HUWE1,ZNF260,KANSL2,GTF2H2,MED22,SPTAN1,DDX24,USP42,HEBP2,LLPH,UTP20,SH3BP5,GPS2,PARG,ACOX1,FAM3C,DBI,AEN,PARP10,WDR13,SNX15,RBM8A,ENSA,NENF,RUFY1,TRIM65,FANCI,PAPOLA,KRR1,FANCL,GLIS2,TIMM23,INTS1,SLC44A1,POP7,NOC2L,RYBP,PLK1,RPP25,PTPN18,MIOS,RBX1,SNRPB,RAD51AP1,ZBED5,PSMG1,CDC6,UBE2V1,UTP3,PBRM1,EAF2,USP21,LSG1,GRIPAP1,CHD3,E2F4,ZNF367,KPNA2,PRPF4,FAM208A,POT1,CCDC137,ZNF564,FUBP1,ZCCHC9,HJURP,PHB2,CENPF,SDC2,CHCHD2,CDK13,DNAJB1,ARID1B,SUB1,MLX,MBD2,XPA,CTR9,RBM3,ICE2,GLE1,MRPL48,DCAF8,LDB1,METTL22,ARMC8,NPIPA1,APPL1,RXRB,RPL36,SDHB,MBIP,COX7A2L,SIL1,DTD1,RUVBL2,BTBD10,BCCIP,USP7,SART1,SUCLG1,ARID2,LAGE3,PCBP1,LYN,OIP5,MRPL50,NRF1,PSMA6,ZNF473,BRPF3,KMT5C,PIN1,PPME1,TARDBP,TOP1MT,STRAP,CTDSP2,SPIDR,PRPF19,PPIF,KDM3B,BIRC3,POLR2G,PPT1,PPIE,DCLRE1C,VDAC1,MRPS14,AFDN,SUGP1,IDE,DHX16,RBL1,FASTK,UHRF2,XRCC3,H3F3A,CHID1,SMAD4,RAD51D,NIFK,CMAS,MCM10,C19orf53,MTERF1,PDAP1,AGO2,CDCA8,GTF3A,HMGN3,PAGR1,TUBGCP2,DNAJB9,CTSS,POLR1B,ORC3,RBM15B,YTHDC1,PPAN,RPRD1A,ACP2,BTAF1,PRKDC,TUFM,TOP3A,RANGAP1,PCGF1,HAGH,API5,DDX23,L3MBTL3,NEIL3,BBX,E2F1,IMPDH1,RBPJ,TAF12,NR2F2,PGAM1,HIPK3,IFI16,MAX,H2AFZ,PNISR,PRKCSH,ADAM10,CXXC1,USP39,CUL1,GYG1,OAT,UBE2I,PARK7,PA2G4,NOL11,TRA2B,SUCLG2,TAF5L,SMARCE1,SRSF10,CDC5L,NSUN2,SUPT20H,USP22,RFC2,CBFB,CLNS1A,EIF3A,PRIM1,IWS1,DOT1L,ZMYM3,MKNK1,KIF18B,BRD2,RPS14,TPP2,LUC7L3,MRPL27,PTPDC1,CCDC59,ZMAT3,NMD3,B4GALT2,RECQL,C9orf78,EWSR1,SCOC,POLR2K,PRKAA1,CYCS,SUPT7L,VPS25,NDUFS7,NPLOC4,WDR48,YY1AP1,C12orf10,TMEM250,EXOSC7,ARPC5,MSH2,OSTF1,MRPL40,TNRC18,MRM3,APOL1,GID8,GCC2,PRIM2,ELL2,RPS24,C1orf35,EXOSC9,ARID1A,FXR1,PTTG1IP,CCT8,TWISTNB,PHF6,XRCC5,CAT,MTHFD2,EPOP,RBMX,MED15,PIAS2,APPL2,ARAP1,CEBPG,CABIN1,GPI,CYTIP,TP53RK,ATXN3,RAF1,UROD,POMP,BCL2L1,C2orf49,NUDT19,DECR1,CCNA2,MRPS27,TAP2,TTC3,TP53BP2,RNASEH2A,AQR,ILKAP,CDK12,CFL1,SAP30,BRD4,NARF,VDAC2,ELP4,EDF1,PKMYT1,TRIM28,SUPT16H,RAD51C,HINT1,DSN1,DGCR8,SAFB,ATF6,BEND3,XRCC4,EYA2,PRPF4B,NDUFS1,MANBA,TKT,FAM76A,CBLL1,ARGLU1,RFWD3,CCNK,DNAJC8,PTPN11,MRPL54,FEM1B,CARF,CNN2,CITED2,MTX2,MSH6,KAT2A,RFXANK,BMS1,ARSK,KLF6,SPPL2B,CBX3,ZHX1,DDX5,DUSP11,NDUFS5,TAF6,PURA,DDB1,IPO4,DEF6,POLA2,RORB,CCNC,LYRM4,KMT2E,COMMD5,BRIX1,MRPL19,SF3B2,PCYOX1L,GOT2,SIVA1,JAZF1,HADHB,RPF2,TCEA1,SLC35C2,CARMIL1,CARM1,SRPK2,LARS,DEAF1,SNRNP200,LAP3,VHL,RIOX2,SREK1,SUMF2,KMT2C,ASF1B,EIF4ENIF1,BRWD1,NIP7,PPM1G,U2SURP,SH3GLB2,CRCP,BAZ1B,CAB39,STK11,CHEK2,CLU,MRPL13,DCAF5,CAPN1,UBE2D3,NSMCE4A,PPP1R12A,ZCCHC8,THRAP3,PM20D2,RGS2,TTF1,QSOX2,NUP205,PRPF18,LYAR,DTL,MED10,ZRANB1,MCPH1,POLR2I,CREG1,SUGP2,GBA,SYVN1,SLTM,DAPK3,MASTL,UAP1,SIAH2,CTSA,YWHAZ,SNRNP70,C11orf1,TSEN15,TCF12,PRKAB1,SNX27,MDH2,PMS2,SMARCA4,ORC1,MXD1,SAP130,HNRNPA2B1,RRN3,NVL,CD3EAP,EXOSC1,CS,UTP4,CSTF1,UBQLN4,NXT1,PCGF6,SMU1,LSM8,ATXN1,OGDH,EDEM2,TOLLIP,FANCE,MBD3,PDHX,RPS9,ALKBH6,HNRNPR,STAT6,ARNTL,ANP32E,FKBP5,MAPK1,CWC25,DNAJC2,TRIP12,RAE1,SHPRH,PAWR,GFM2,PIP4K2A,FERMT3,MZT2A,KLHL20,KMT5A,PPIG,NABP2,H2AFY,ANP32A,NDUFS8,FBL,STAT3,MICAL3,TGFB1,PPP1R9B,DCAF6,FAM49B,TIMMDC1,PSPC1,HELB,MIER1,RFFL,NADK2,RCOR1,PRMT2,CTSL,UPF1,KMT2B,ACAT1,CENPT,ZMIZ1,TERF1,ADD1,MRPS15,KDM4A,XIAP,DHX8,GLUD1,PPP1R16B,ANKRD23,MIS12,CDK5,PSMD1,NEK6,NSRP1,SRSF4,PDS5B,NUP153,SENP1,PCBP2,MLST8,PLK3,ZNF672,AATF,MRPL43,TOPORS,MCL1,SMC2,STOML2,BRMS1,PWWP2B,LIMK1,PRDX5,MLYCD,FBXL3,TFDP2,E2F2,LONP2,AAAS,DDX42,SSRP1,MRPL9,PHF23,MRPS2,TOP2B,EZH1,LMNA,DDRGK1,GNS,DDX56,INTS7,MCM5,ZNF326,RTCB,CARS2,TIMM8B,CYFIP1,ETV3,PRRC2A,ZMYND11,TEX10,MYBL2,RPS10,SRSF5,MPG,ABCF1,MATR3,SCARB2,OSBPL11,CCDC86,POLR2J,DUSP3,SETD3,HEXA,SGF29,ZNF207,FAM208B,SARNP,TRERF1,IVNS1ABP,CHD1L,RMI2,WDTC1,NUF2,RXYLT1,NIT2,PRKACA,SAFB2,APP,KTN1,CLUAP1,PRKD3,ATP2A2,SP100,UTP18,DUT,GRSF1,DDA1,NUP107,ANAPC7,FAM76B,RBM15,CLN6,ATF2,RNF169,SHOC2,PSRC1,INTS13,RNPS1,WBP2,ATP6V0A1,NUSAP1,CDCA2,NDUFA7,DDX17,TAF2,CDC16,HIPK2,PDXK,FUS,ZBTB11,GEN1,COIL,RPS2,GMCL1,JMJD6,AKT1S1,ETS1,PNO1,KRI1,FBXO3,ADD3,SUV39H2,PPP1R8,PRDM4,GEMIN6,GTSE1,HNRNPM,NUDC,PDPK1,PPP3CA,POLK,GALC,MRPS10,DDX39A,RPA1,KEAP1,POLE,WNT5B,TATDN2,PITX1,MAPK6,LRPPRC,PML,HMGB2,PSAP,USF2,ANAPC4,DDX47,THOC1,AGRN,MCCC1,CSNK2A1,EBNA1BP2,KCMF1,GIT2,LIN9,PCNA,ZNF639,TRMU,ETV6,XRCC2,ZFYVE27,MCMBP,MRPL32,CCAR1,METTL1,SP3,EXOSC6,BAZ2A,MRPL12,EZR,BRCA1,ANLN,PRKRA,OPTN,TIMM13,CDCA4,TONSL,NAGLU,ACTB,DHFR2,ZNF45,SINHCAF,GEMIN7,TMUB1,ASAH1,CTCF,RACGAP1,PPP3CB,ASXL2,SNRNP25,RB1,MED8,VMP1,PPIL2,TIMELESS,AFF1,MDFIC,MAML1,NQO2,UTP15,RTF1,ZNF174,PSMC4,PALB2,SYNCRIP,CDC27,SNAP23,TBPL1,PRMT7,ATP5F1A,FOXM1,MRPL39,XAB2,SUMO2,COPE,HCFC1R1,RPAIN,COMMD8,RPL11,RAD23A,ZBTB21,PDK2,MDM2,TNFAIP8,MRPL34,MINPP1,SAP30L,DVL2,POC5,GM2A,TIMP2,RPL35,CPOX,DNAJC9,NFATC2,PRPF3,KDM1B,TXNL4A,USP36,RPSA,SRSF1,MRPL2,DNAJC10,CLK3,TIMM17A,PSMD3,MAFK,ZNF436,NCOA1,LTA4H,ZNF146,INTS2,CTDP1,GOLIM4,CDC40,MIF4GD,CDT1,ARID5A,SMC6,NKRF,SUMF1,CSNK1A1,RMI1,WRNIP1,PTPN2,IRF4,GSTK1,CWC27,SS18L1,DDX31,CENPM,PTGES3,CAMK2G,ZMYM5,FAM50B,PPWD1,NEU1,KPNA4,CDKN2AIPNL,GOLGA7,BIRC5,TFE3,SNAP29,CDCA7L,ACADM,UBE2C,GCSH,ZNF496,NDUFB6,NHLRC3,CCNB1,POLR3K,UTP25,CYB5RL,PARPBP,CDC25B,DNMT1,NOL12,USO1,AKT2,ARHGAP45,NOL8,ELOA,MKI67,DDX20,MRNIP,AURKB,SLC25A5,MAK16,PSMD8,WDR4,EIF2D,PTPN7,DHTKD1,RRS1,HDAC2,PPIB,HSPH1,MUT,GMFG,CHTF18,KIF23,PMF1,NOTCH2,MAN2B1,METTL3,JMY,HDAC7,BDH1,GNAI2,EEF1D,TERF2,MORC3,PHF10,FTL,DDX28,PKM,KDM3A,SF3A2,PATL1,PSMB3,FAS,SERTAD2,QARS,ACLY,PPP3R1,DCAF11,VCPIP1,TCOF1,YY1,PPP6R3,CDK2,NRBP1,DNMT3A,TRIP10,RPS6KA1,SUZ12,SF3B1,URB2,OLA1,SDHA,PHC2,FLAD1,CRKL,TERF2IP,CYHR1,APLP2,SHC1,KDM2A,UCHL5,TNPO2,CDKN1B,TALDO1,MRM2,GPX4,CCT2,CDKN2AIP,RFC3,ERF,LYRM1,CUL3,SLBP,CDC23,POLG2,PSMB9,GAR1,H2AFV,AP4E1,CENPU,NSA2,VEZF1,MRPL55,TBL3,FAAP100,H2AFX,STAT1,PPA2,PDCD11,ATMIN,CSNK1D,POLQ,NCOR2,TWNK,MRI1,TCF3,BABAM1,SDF2L1,BLM,SPR,FOXO3,MAD2L2,GTF2F1,PIP5K1C,RBM17,PTEN,CRAT,CENPJ,COPS7B,MAP3K14,CREB1,CNPY3,UBE2M,NCOA2,SMC4,ZFP64,DENND1B,NEK7,WDR18,ILF3,TBRG4,ANAPC2,MARK2,POLR2A,NUCB1,SGSH,PRDX3,HNRNPH3,TFDP1,NAXE,KHSRP,ASNA1,BYSL,DDX52,S100PBP,ADA2,IER2,HNRNPAB,NOP2,UBN1,NF1,ALKBH5,UBE2Z,SIRT2,TAF6L,USP48,SNRPD3,MAPK14,SNAPC4,CUTC,BCAT2,MBD4,UBLCP1,EIF4A3,IMPAD1,METTL14,SRI,AKR1B1,KIF22,RP2,NFU1,OGG1,ARID4A,ELOF1,TIMM50,COPS8,FYTTD1,TRIM8,WDR82,SOX4,DHX15,CHAF1A,PAF1,GEMIN5,UBTF,SPATA2,TIMM29,ATXN2L,IARS2,PQBP1,ROCK1,COPS6,RPS26,PSMC1,RPS15,AGTRAP,ZNF768,CIB1,MED13L,TIA1,MEF2A,SRRT,NFATC3,BANF1,ZNF335,BUD31,YBX1,BCL2,KIFAP3,ACAD8,HP1BP3,CIC,OXR1,PSMA1,ISG15,CAND1,RBM25,NSMF,CDCA5,RBBP4,HNRNPDL,MZT2B,PDSS2,SMARCD1,MBD1,ASH1L,MPHOSPH8,CHERP,HNRNPUL2,NSD3,IRF3,CHD1,MEAF6,ANKRD28,BABAM2,AKAP8,APOOL,CHTOP,PDIA6,HTRA2,RLIM,ACSL5,ZNF500,PSMB7,NLN,ERBIN,NDUFB1,GFER,DAP3,TAB2,TULP3,CHCHD1,CANT1,AKNA,USP11,SMURF1,CBX4,MIF,MRPL42,CASP6,EYA1,TOR3A,SRGN,DBF4,MRPS26,LETMD1,FBXO5,CTNNBL1,BRD7,MRPL11,GINS1,TELO2,GTF3C6,HMGN1,NASP,POLR3GL,MEN1,SYMPK,SNRPA,MAPK3,HSPA1B,ATAD2,ZNF330,ZRANB2,SRSF3,MBD6,TATDN1,IDH3B |
| 3.610e-93 | -212.86 | membrane-enclosed lumen | cellular component | GO:0031974 | 5182 | 1227 | 18223 | 2701 |
ZBTB10,HEXB,TGOLN2,LACTB2,CCNL2,RBM4,RPL23A,USF1,RAD23B,MECR,CRY2,ECD,MOB1A,LRRC59,ZNRD1,RHBDD2,FTSJ3,MRPL57,ERCC1,GABPA,EHMT1,HNRNPF,WDHD1,NUTF2,MCM2,COA7,GINS4,SMAD2,RAD18,RPS27A,OGT,RNASEL,SMAD1,ANXA11,SMNDC1,NXT2,CLSPN,GGA1,DHX9,PDCD7,PSMD9,PARN,CDC73,TMEM179B,SMC3,RBM34,EFTUD2,GEMIN4,MYDGF,MRPL21,CPSF4,MVP,NSUN4,LUC7L2,SRSF11,EIF3L,AGGF1,FOXK1,MAPKAPK3,MTA2,SF3B6,ERO1A,GTPBP4,USP10,BCLAF1,MRPL16,ELK1,MAGED2,KPNA1,TXNDC16,ETS2,WIPI2,ZNF830,ACSF2,MRPL3,KARS,TRIM41,TPX2,INO80E,DAZAP2,CPNE3,ZNF420,AHCTF1,MTA1,TBC1D14,GMEB1,NSFL1C,NABP1,MICU2,INTS12,ZC3H3,RPRD1B,CGGBP1,CPNE1,POLR2L,EID1,FAM118B,KAT7,IDH3A,CRNKL1,CIRBP,POLR2D,E2F3,PFKFB3,GORAB,MEF2D,GSTCD,KIF2A,LSM6,NSMCE2,RNF38,SNRPG,PPP5C,PITRM1,TUBB,USP13,SRSF6,ZFP91,HABP4,TRMT6,ATG2B,ABHD14B,ATP5F1B,IP6K2,WDR5,RRP36,SAPCD2,TUT4,NEIL2,GOLM1,RPA2,PSMD2,CLIC4,HUWE1,ZNF260,KANSL2,GTF2H2,MED22,SPTAN1,DDX24,USP42,HEBP2,LLPH,UTP20,SH3BP5,GPS2,PARG,ACOX1,FAM3C,DBI,AEN,PARP10,WDR13,SNX15,RBM8A,ENSA,NENF,RUFY1,TRIM65,FANCI,PAPOLA,KRR1,FANCL,GLIS2,TIMM23,INTS1,SLC44A1,POP7,NOC2L,RYBP,PLK1,RPP25,PTPN18,MIOS,RBX1,SNRPB,RAD51AP1,ZBED5,PSMG1,CDC6,UBE2V1,UTP3,PBRM1,EAF2,USP21,LSG1,GRIPAP1,CHD3,E2F4,ZNF367,KPNA2,PRPF4,FAM208A,POT1,CCDC137,ZNF564,FUBP1,ZCCHC9,HJURP,PHB2,CENPF,SDC2,CHCHD2,CDK13,DNAJB1,ARID1B,SUB1,MLX,MBD2,XPA,CTR9,RBM3,ICE2,GLE1,MRPL48,DCAF8,LDB1,METTL22,ARMC8,NPIPA1,APPL1,RXRB,RPL36,SDHB,MBIP,COX7A2L,SIL1,DTD1,RUVBL2,BTBD10,BCCIP,USP7,SART1,SUCLG1,ARID2,LAGE3,PCBP1,LYN,OIP5,MRPL50,NRF1,PSMA6,ZNF473,KMT5C,BRPF3,PIN1,PPME1,TARDBP,TOP1MT,STRAP,CTDSP2,SPIDR,PRPF19,PPIF,KDM3B,BIRC3,POLR2G,PPT1,PPIE,DCLRE1C,VDAC1,MRPS14,AFDN,SUGP1,IDE,DHX16,RBL1,FASTK,UHRF2,XRCC3,H3F3A,CHID1,SMAD4,RAD51D,NIFK,CMAS,C19orf53,MCM10,MTERF1,PDAP1,AGO2,CDCA8,GTF3A,HMGN3,PAGR1,TUBGCP2,DNAJB9,CTSS,POLR1B,ORC3,RBM15B,YTHDC1,PPAN,RPRD1A,ACP2,BTAF1,PRKDC,TUFM,TOP3A,RANGAP1,PCGF1,HAGH,API5,DDX23,L3MBTL3,NEIL3,BBX,E2F1,IMPDH1,RBPJ,TAF12,NR2F2,PGAM1,HIPK3,IFI16,MAX,H2AFZ,PNISR,PRKCSH,ADAM10,CXXC1,USP39,CUL1,GYG1,OAT,UBE2I,PARK7,PA2G4,NOL11,TRA2B,SUCLG2,TAF5L,SMARCE1,SRSF10,CDC5L,NSUN2,SUPT20H,USP22,CBFB,RFC2,CLNS1A,EIF3A,PRIM1,IWS1,DOT1L,ZMYM3,MKNK1,KIF18B,BRD2,RPS14,TPP2,LUC7L3,MRPL27,PTPDC1,CCDC59,ZMAT3,NMD3,B4GALT2,RECQL,C9orf78,EWSR1,SCOC,POLR2K,PRKAA1,CYCS,SUPT7L,VPS25,NDUFS7,NPLOC4,WDR48,YY1AP1,C12orf10,TMEM250,EXOSC7,ARPC5,MSH2,OSTF1,MRPL40,TNRC18,MRM3,APOL1,GID8,GCC2,PRIM2,ELL2,RPS24,C1orf35,EXOSC9,ARID1A,FXR1,PTTG1IP,CCT8,TWISTNB,PHF6,XRCC5,CAT,MTHFD2,EPOP,RBMX,MED15,PIAS2,APPL2,ARAP1,CEBPG,CABIN1,GPI,CYTIP,TP53RK,ATXN3,RAF1,UROD,POMP,BCL2L1,C2orf49,NUDT19,DECR1,CCNA2,MRPS27,TAP2,TTC3,TP53BP2,RNASEH2A,AQR,ILKAP,CDK12,CFL1,SAP30,BRD4,NARF,VDAC2,ELP4,EDF1,PKMYT1,TRIM28,SUPT16H,RAD51C,HINT1,DSN1,DGCR8,SAFB,ATF6,BEND3,XRCC4,EYA2,PRPF4B,NDUFS1,MANBA,TKT,FAM76A,CBLL1,ARGLU1,RFWD3,CCNK,DNAJC8,PTPN11,MRPL54,FEM1B,CARF,CNN2,CITED2,MTX2,MSH6,KAT2A,RFXANK,BMS1,ARSK,KLF6,SPPL2B,CBX3,ZHX1,DDX5,DUSP11,NDUFS5,TAF6,PURA,DDB1,IPO4,DEF6,POLA2,RORB,CCNC,LYRM4,KMT2E,COMMD5,BRIX1,MRPL19,SF3B2,PCYOX1L,GOT2,SIVA1,JAZF1,HADHB,RPF2,TCEA1,SLC35C2,CARMIL1,CARM1,SRPK2,LARS,DEAF1,SNRNP200,LAP3,VHL,RIOX2,SREK1,SUMF2,KMT2C,ASF1B,EIF4ENIF1,BRWD1,NIP7,PPM1G,U2SURP,SH3GLB2,CRCP,BAZ1B,CAB39,STK11,CHEK2,CLU,MRPL13,DCAF5,CAPN1,UBE2D3,NSMCE4A,PPP1R12A,ZCCHC8,THRAP3,PM20D2,RGS2,TTF1,QSOX2,NUP205,PRPF18,LYAR,DTL,MED10,ZRANB1,MCPH1,POLR2I,CREG1,SUGP2,GBA,SYVN1,SLTM,DAPK3,MASTL,UAP1,SIAH2,CTSA,YWHAZ,SNRNP70,C11orf1,TSEN15,TCF12,PRKAB1,SNX27,MDH2,PMS2,SMARCA4,ORC1,MXD1,SAP130,HNRNPA2B1,RRN3,NVL,CD3EAP,EXOSC1,CS,UTP4,CSTF1,UBQLN4,NXT1,PCGF6,SMU1,ATXN1,LSM8,OGDH,EDEM2,TOLLIP,FANCE,MBD3,PDHX,RPS9,ALKBH6,HNRNPR,STAT6,ARNTL,ANP32E,FKBP5,MAPK1,CWC25,DNAJC2,TRIP12,RAE1,SHPRH,PAWR,GFM2,PIP4K2A,FERMT3,MZT2A,KLHL20,KMT5A,PPIG,NABP2,H2AFY,ANP32A,NDUFS8,FBL,STAT3,MICAL3,TGFB1,PPP1R9B,DCAF6,FAM49B,TIMMDC1,PSPC1,HELB,MIER1,RFFL,NADK2,RCOR1,PRMT2,CTSL,UPF1,KMT2B,ACAT1,CENPT,ZMIZ1,TERF1,ADD1,MRPS15,KDM4A,XIAP,DHX8,GLUD1,PPP1R16B,ANKRD23,MIS12,CDK5,PSMD1,NEK6,NSRP1,SRSF4,PDS5B,NUP153,SENP1,PCBP2,MLST8,PLK3,ZNF672,AATF,MRPL43,TOPORS,MCL1,SMC2,STOML2,BRMS1,PWWP2B,LIMK1,PRDX5,MLYCD,FBXL3,TFDP2,E2F2,LONP2,AAAS,DDX42,SSRP1,MRPL9,PHF23,MRPS2,TOP2B,EZH1,LMNA,DDRGK1,GNS,DDX56,INTS7,MCM5,ZNF326,RTCB,CARS2,TIMM8B,CYFIP1,ETV3,PRRC2A,ZMYND11,TEX10,MYBL2,RPS10,SRSF5,MPG,ABCF1,MATR3,SCARB2,OSBPL11,CCDC86,POLR2J,DUSP3,SETD3,HEXA,SGF29,ZNF207,FAM208B,SARNP,TRERF1,IVNS1ABP,CHD1L,RMI2,WDTC1,NUF2,RXYLT1,NIT2,PRKACA,SAFB2,APP,KTN1,CLUAP1,PRKD3,ATP2A2,SP100,UTP18,DUT,GRSF1,DDA1,NUP107,ANAPC7,FAM76B,RBM15,CLN6,ATF2,RNF169,SHOC2,PSRC1,INTS13,RNPS1,WBP2,ATP6V0A1,NUSAP1,CDCA2,NDUFA7,DDX17,TAF2,CDC16,HIPK2,PDXK,FUS,ZBTB11,GEN1,COIL,RPS2,GMCL1,JMJD6,AKT1S1,ETS1,PNO1,KRI1,FBXO3,ADD3,SUV39H2,PPP1R8,PRDM4,GEMIN6,GTSE1,HNRNPM,NUDC,PDPK1,PPP3CA,POLK,GALC,MRPS10,DDX39A,RPA1,KEAP1,POLE,WNT5B,TATDN2,PITX1,MAPK6,LRPPRC,PML,HMGB2,PSAP,USF2,ANAPC4,DDX47,AGRN,THOC1,MCCC1,CSNK2A1,EBNA1BP2,KCMF1,GIT2,LIN9,PCNA,ZNF639,TRMU,ETV6,XRCC2,ZFYVE27,MCMBP,MRPL32,CCAR1,METTL1,SP3,EXOSC6,BAZ2A,MRPL12,EZR,BRCA1,ANLN,PRKRA,OPTN,TIMM13,CDCA4,TONSL,NAGLU,ACTB,DHFR2,ZNF45,SINHCAF,GEMIN7,TMUB1,ASAH1,CTCF,RACGAP1,PPP3CB,ASXL2,SNRNP25,RB1,MED8,VMP1,PPIL2,TIMELESS,AFF1,MDFIC,MAML1,NQO2,UTP15,RTF1,ZNF174,PSMC4,SYNCRIP,PALB2,CDC27,SNAP23,TBPL1,PRMT7,ATP5F1A,FOXM1,MRPL39,XAB2,SUMO2,COPE,HCFC1R1,RPAIN,COMMD8,RPL11,RAD23A,ZBTB21,PDK2,MDM2,TNFAIP8,MRPL34,MINPP1,SAP30L,DVL2,POC5,GM2A,TIMP2,RPL35,CPOX,DNAJC9,NFATC2,PRPF3,KDM1B,TXNL4A,USP36,RPSA,SRSF1,MRPL2,DNAJC10,CLK3,TIMM17A,PSMD3,MAFK,ZNF436,NCOA1,LTA4H,ZNF146,INTS2,CTDP1,GOLIM4,CDC40,MIF4GD,CDT1,ARID5A,SMC6,NKRF,SUMF1,CSNK1A1,RMI1,WRNIP1,PTPN2,IRF4,GSTK1,CWC27,SS18L1,DDX31,CENPM,PTGES3,CAMK2G,ZMYM5,FAM50B,PPWD1,NEU1,KPNA4,CDKN2AIPNL,GOLGA7,BIRC5,TFE3,SNAP29,CDCA7L,ACADM,UBE2C,GCSH,ZNF496,NDUFB6,NHLRC3,CCNB1,POLR3K,UTP25,CYB5RL,PARPBP,CDC25B,DNMT1,NOL12,USO1,AKT2,ARHGAP45,NOL8,ELOA,MKI67,DDX20,MRNIP,AURKB,SLC25A5,MAK16,PSMD8,WDR4,EIF2D,PTPN7,DHTKD1,RRS1,HDAC2,PPIB,HSPH1,MUT,GMFG,CHTF18,KIF23,PMF1,NOTCH2,MAN2B1,METTL3,JMY,HDAC7,BDH1,GNAI2,EEF1D,MORC3,TERF2,FTL,PHF10,DDX28,PKM,KDM3A,SF3A2,PATL1,PSMB3,FAS,SERTAD2,QARS,ACLY,PPP3R1,DCAF11,VCPIP1,TCOF1,YY1,PPP6R3,CDK2,NRBP1,DNMT3A,TRIP10,RPS6KA1,SUZ12,SF3B1,URB2,OLA1,SDHA,PHC2,FLAD1,CRKL,TERF2IP,CYHR1,APLP2,SHC1,KDM2A,UCHL5,TNPO2,CDKN1B,TALDO1,MRM2,GPX4,CCT2,CDKN2AIP,RFC3,ERF,LYRM1,CUL3,SLBP,CDC23,POLG2,PSMB9,GAR1,H2AFV,AP4E1,CENPU,NSA2,VEZF1,MRPL55,TBL3,FAAP100,H2AFX,STAT1,PPA2,PDCD11,CSNK1D,ATMIN,POLQ,NCOR2,TWNK,TCF3,MRI1,BABAM1,SDF2L1,BLM,SPR,FOXO3,MAD2L2,GTF2F1,PIP5K1C,RBM17,PTEN,CRAT,CENPJ,COPS7B,MAP3K14,CREB1,CNPY3,UBE2M,NCOA2,SMC4,ZFP64,DENND1B,NEK7,WDR18,ILF3,TBRG4,ANAPC2,MARK2,POLR2A,NUCB1,SGSH,PRDX3,HNRNPH3,TFDP1,KHSRP,NAXE,ASNA1,BYSL,DDX52,S100PBP,ADA2,IER2,HNRNPAB,NOP2,UBN1,NF1,ALKBH5,UBE2Z,SIRT2,TAF6L,USP48,SNRPD3,MAPK14,SNAPC4,CUTC,BCAT2,MBD4,UBLCP1,EIF4A3,IMPAD1,METTL14,SRI,AKR1B1,KIF22,RP2,NFU1,OGG1,ARID4A,ELOF1,TIMM50,COPS8,FYTTD1,TRIM8,WDR82,SOX4,DHX15,CHAF1A,PAF1,GEMIN5,UBTF,SPATA2,TIMM29,ATXN2L,IARS2,PQBP1,ROCK1,COPS6,RPS26,PSMC1,RPS15,AGTRAP,ZNF768,CIB1,MED13L,TIA1,MEF2A,SRRT,NFATC3,BANF1,BUD31,ZNF335,YBX1,KIFAP3,BCL2,ACAD8,HP1BP3,CIC,OXR1,PSMA1,ISG15,CAND1,RBM25,NSMF,CDCA5,RBBP4,HNRNPDL,MZT2B,PDSS2,SMARCD1,MBD1,ASH1L,MPHOSPH8,CHERP,HNRNPUL2,NSD3,IRF3,CHD1,MEAF6,ANKRD28,BABAM2,AKAP8,APOOL,CHTOP,PDIA6,HTRA2,RLIM,ACSL5,ZNF500,PSMB7,NLN,ERBIN,NDUFB1,GFER,DAP3,TAB2,TULP3,CHCHD1,CANT1,AKNA,USP11,SMURF1,CBX4,MIF,MRPL42,CASP6,EYA1,TOR3A,SRGN,DBF4,MRPS26,LETMD1,FBXO5,CTNNBL1,BRD7,MRPL11,GINS1,TELO2,GTF3C6,HMGN1,NASP,POLR3GL,MEN1,SYMPK,SNRPA,MAPK3,HSPA1B,ATAD2,ZNF330,ZRANB2,MBD6,SRSF3,TATDN1,IDH3B |
| 8.721e-86 | -195.86 | NTRK1 (neurotrophic receptor tyrosine kinase 1) | protein interactions | 4914 | 1952 | 644 | 17029 | 2761 |
CCDC93,ADD1,TSC2,DHX8,GLUD1,RBM4,PABPC4,CDK5,PSMD1,RAD23B,AP1M1,PDS5B,DNM2,LRRC59,FTSJ3,PCBP2,RHOBTB3,HSDL1,HNRNPF,KIF15,WDHD1,SMC2,MCM2,STOML2,WDR11,OGT,AAAS,PFKP,PDCD4,ANXA11,SSRP1,DDX42,MRPS2,TRIO,STRN4,DHX9,CERK,TOP2B,CDC73,COPB2,LMNA,DDX56,PDXP,EIF2S2,SMC3,MCM5,EFTUD2,RTCB,TNPO3,GEMIN4,PPP6R1,PABPC1,PPA1,NUP85,LUC7L2,SRSF11,CYFIP1,EIF3L,RBM42,FOXK1,PRRC2A,DHX29,MTA2,TEX10,ERO1A,GTPBP4,USP10,BCLAF1,MAP7D1,SRSF5,EIF4H,ABCF1,MATR3,RDH11,PTPRF,MAGED2,SCARB2,OSBPL11,KPNA1,MDH1,RUFY3,PDLIM5,MRPL3,ZNF207,EXOC3,KARS,CHD1L,ACTR3,MYH9,NUF2,EFL1,GLRX3,STAM,REPS1,KTN1,CPNE3,ATP2A2,ZKSCAN1,MTA1,NUP107,RBM15,DCTN1,CPNE1,MAP4K4,CRNKL1,ATP6V0A1,DNAJA1,TANC1,FKBP3,MAT2A,DDX17,PPP2CA,KIF2A,CHCHD3,SEC61A1,VPS26B,WDR7,FUS,PPP5C,TUBB,LRCH1,RPS2,ANXA6,SRSF6,TRMT6,ATG2B,UBE4A,ATP5F1B,WDR5,HDGFL2,CAPN2,PSMD2,CLIC4,HUWE1,ARHGEF1,DCP1A,LTN1,ANXA5,NAP1L4,TTLL12,HNRNPM,NUDC,LDHB,SPTAN1,STAU1,DDX24,LDHA,DDX39A,PICALM,CIP2A,RPA1,POLE,CCDC6,PARG,CAPN7,PML,LRPPRC,HMGB2,YWHAH,FAF1,GPATCH4,TMEM131,SRM,YTHDC2,MCCC1,CSNK2A1,SND1,SEC16A,RUFY1,FANCI,SSR1,PAPOLA,ABL2,PCNA,NUP210,INTS1,PIK3R2,TXLNA,NOC2L,EIF5,MCMBP,CCAR1,TACC3,CDC37,PLK1,SEPT9,MIOS,PBXIP1,HARS,EZR,ESYT1,LUC7L,LSG1,EPB41,DPYSL3,TONSL,PRPF4,KPNA2,C2CD5,FUBP1,PHB2,KLC1,CDK13,DNAJB1,NCKAP1,RB1,CCP110,KIF13B,PPIL2,TIMELESS,CTR9,SLC27A4,AHCY,ALDH18A1,ABCC1,NIPSNAP1,TRAPPC9,ACSL3,CAMSAP1,RTF1,MAP4K3,UBE4B,EIF4G2,APPL1,PSMC4,PCM1,SYNCRIP,CDC27,RUVBL2,ATP5F1A,ECPAS,BCCIP,USP7,SART1,UGP2,XAB2,MRPL39,DYNLL1,TOR1AIP1,COPE,ATP6V1B2,PCBP1,LYN,BCAP31,CSDE1,PSMA6,PPME1,RPAP1,TARDBP,LMAN1,STRAP,DVL2,PRPF19,KDM3B,CLPTM1,ARHGAP17,RPL29,TUBGCP5,DNAJC9,NUP155,PRPF3,VDAC1,RPSA,EIF3H,SRSF1,AFDN,DNAJC10,IDE,ATP1A1,RBL1,DHX16,PSMD3,LTA4H,MCM10,GOLIM4,AGO2,GNE,TMX3,SMC6,NKRF,CDK11B,CSNK1A1,NCAPG,SCYL2,TUBGCP2,BZW2,TFRC,WRNIP1,DDX31,ABCD1,POLR1B,ORC3,RBM15B,RPAP3,SNX2,PRKDC,BTAF1,ABCF2,TUFM,TOP3A,RANGAP1,ARHGEF12,PPWD1,API5,RHOT2,DDX23,SEC23IP,GLG1,IMPDH1,ACADM,PGAM1,NUP188,TXN,PDCD6IP,PRKCSH,YTHDF3,USP39,CUL1,NANS,OAT,MYEF2,UTP25,PA2G4,ASAP2,TRA2B,AP2B1,TFG,DNMT1,CDC5L,SRSF10,SRP72,USO1,NSUN2,ELOA,DDX20,SLC25A5,CLNS1A,EIF3A,STT3A,PSMD8,TPP2,LUC7L3,MAP4,ITGB1,DHTKD1,ZNF598,HDAC2,PPIB,RECQL,HSPH1,EWSR1,MAPRE1,MUT,CHTF18,PRKAA1,VAV2,DNAAF5,RRM1,COPG2,PDXDC1,CNOT3,NPLOC4,WDR48,RPN1,ATIC,PPP4R1,MSH2,CTPS1,CYC1,PIKFYVE,LPCAT1,FAM171A1,EEF1D,DDX28,PRIM2,PIGT,WDR1,ZNF574,EXOSC9,PKM,CYFIP2,FXR1,PATL1,MTR,CCT8,PHF6,XRCC5,AKAP1,CAT,SEC31A,EPRS,HSPBP1,GOLGA2,NSF,DCK,RBMX,QARS,ACLY,APPL2,ARAP1,VCPIP1,TCOF1,GPI,SMPD4,PPP6R2,PPP6R3,CDK2,ZC3HAV1,SF3B1,RPS6KA1,MAGED1,EIF3D,OLA1,AP1B1,SDHA,CRKL,DECR1,SHC1,UCHL5,MRPS27,TNPO2,AQR,TALDO1,NAA35,CFL1,ANKLE2,CCT2,ATP13A1,RFC3,TAOK1,CUL3,VDAC2,LRRC8A,TRIM28,EML4,DHX57,SUPT16H,HSPA4,JAK1,DDOST,TBL3,SAFB,STAT1,SEL1L,NCLN,BEND3,PDCD11,DYNC1LI2,PRPF4B,NDUFS1,SCAMP3,MRI1,TKT,ARGLU1,LANCL1,RAB11A,HLA-A,HEATR5B,WWP2,GTF2F1,RPL17,AHSA1,PTPN11,UPF2,RPL19,MSH6,SMC4,FOCAD,STRIP1,ILF3,RPL8,TBRG4,ADSL,PACS1,RHOT1,KIF11,MARK2,PRDX1,ECH1,POLR2A,PLD3,HGS,MFAP1,HNRNPH3,KHSRP,DDX5,ASNA1,WDR91,TAF6,PURA,DDB1,IPO4,ESYT2,ST13,HNRNPAB,NOP2,COPA,MOGS,KIF2C,TAF6L,USP48,UBQLN2,BRIX1,MRPL19,EDC3,SF3B2,RAP1A,EIF4A3,THADA,GOT2,DPYSL2,HADHB,AKR1B1,TECR,CARM1,SRPK2,LARS,SNRNP200,DPM1,LAP3,RRM2,SREK1,WDR82,SLC25A22,PITPNB,OGFR,DHX15,GEMIN5,PAF1,UBTF,U2SURP,PPM1G,ATXN2L,IARS2,ROCK1,COPS6,PSMC1,CAPN1,PPP1R12A,ZCCHC8,NACA,TIA1,EPN1,RPL15,THRAP3,XPO7,SRRT,NUP205,CAPZA1,YBX1,KIFAP3,KNTC1,UBE3C,SLC12A2,HP1BP3,CIC,ERLIN1,GBA,RPL6,PSMA1,EIF2A,CAND1,GNAS,NAP1L1,RBM25,EXOC4,SLC16A1,YWHAZ,RBBP4,EHD4,SNRNP70,NIPSNAP2,HNRNPDL,SMARCD1,TCF12,WASF2,SNX27,IMMT,CORO7,CHERP,MDH2,HNRNPUL2,SMARCA4,CHD1,USP5,ANKRD28,HNRNPA2B1,FARSA,IARS,KIF14,CS,PPP6C,RPN2,PDIA6,OGDH,RPS9,EIF3G,DAP3,HNRNPR,WDR59,FKBP5,USP11,MAPK1,TMEM33,KIF3B,DNAJC2,ZNF316,DCTN2,SCYL1,NUP54,VPS45,MYO9B,XPR1,KIF5B,GART,SEC24C,RRBP1,ARHGEF2,ANP32A,FBL,STAT3,MYO5A,SLC25A1,TXNL1,AMPD2,TELO2,NASP,PSPC1,ATP2C1,COG1,WDR81,SYMPK,TARS,SNRPA,MAPK3,MFN2,CNOT9,UPF1,PLAA,ELMO1,OSBPL8,ACAT1,IDH3B,PLOD3 |
| 2.146e-84 | -192.65 | nucleus | cellular component | GO:0005634 | 7235 | 1534 | 18223 | 2701 |
HECA,ZBTB10,TSC2,TGOLN2,CCNL2,RBM4,ZNF275,FBXO22,RPL23A,CDKN2C,USF1,RAD23B,MECR,DNM2,UPRT,CRY2,ECD,MOB1A,ZNRD1,TIPARP,LRRC59,RHBDD2,FTSJ3,ERCC1,ZNF559,GABPA,EHMT1,HNRNPF,WDHD1,MIER2,NUTF2,DIDO1,COA7,MCM2,GINS4,AHNAK,MID1IP1,SMAD2,RAD18,RPS27A,OGT,RNASEL,SMAD1,ZNF75A,OAZ1,ANXA11,SMNDC1,PDCD4,NXT2,HIVEP3,CLSPN,GGA1,RHOC,MUM1,DHX9,PDCD7,PSMD9,PARN,CDC73,TMEM179B,TFAP4,SMC3,MEGF8,RBM34,FBXO7,EFTUD2,TNPO3,GEMIN4,CPSF4,MVP,NUP85,PABPC1,LUC7L2,SRSF11,EIF3L,IFRD1,AGGF1,RBM42,FOXK1,MAPKAPK3,MTA2,SF3B6,GTPBP4,USP10,BCLAF1,ELK1,MAGED2,KPNA1,ETS2,WIPI2,ZNF830,CFAP20,NUP58,TRIM41,KARS,GGNBP2,PTTG1,TPX2,INO80E,DAZAP2,GLRX3,RCOR3,CPNE3,RBM23,AHCTF1,ZNF420,SH3BP1,MTA1,TBC1D14,UBA5,GMEB1,NABP1,NSFL1C,INTS12,ZNF226,ZC3H3,RPRD1B,CGGBP1,PDCL3,CPNE1,POLR2L,EID1,FAM118B,KAT7,IDH3A,CRNKL1,CIRBP,E2F3,POLR2D,HTATIP2,PFKFB3,GORAB,MEF2D,GSTCD,PPP2CA,KIF2A,LSM6,NSMCE2,CAMKMT,RNF38,CENPBD1,DMWD,SNRPG,PPP5C,TUBB,USP13,COMMD10,ZNF445,SRSF6,ZFP91,TRMT6,HABP4,FLOT1,ABHD14B,ATG2B,IP6K2,ATP5F1B,WDR5,HDGFL2,NEXMIF,RRP36,SAPCD2,NEIL2,TUT4,RPA2,ZBTB45,PSMD2,CLIC4,HUWE1,ZNF260,NAA50,KANSL2,NAP1L4,ZNF710,GTF2H2,MED22,DDX24,TACC1,USP42,LDHA,LLPH,RAB3IP,PICALM,UTP20,SH3BP5,GPS2,ACOX1,PARG,AEN,SSNA1,PARP10,THAP5,WDR13,TRIM11,RBM8A,SNX15,ENSA,NENF,SND1,RUFY1,TRIM65,FANCI,PAPOLA,KRR1,PRNP,CREM,TET3,FANCL,NUP210,GLIS2,INTS1,SLC44A1,POP7,NOC2L,EIF5,MTPN,RYBP,PLK1,RPP25,PTPN18,MIOS,RBX1,RAD51AP1,SNRPB,ZBED5,PSMG1,CDC6,UBE2V1,PBRM1,EAF2,UTP3,LUC7L,USP21,LSG1,CHD3,GRIPAP1,ZNF367,E2F4,PRPF4,KPNA2,CLN3,BEND6,FAM208A,NGLY1,POT1,NUMB,CCDC137,ZNF564,FUBP1,RMND5A,PARP12,ZCCHC9,NEMP2,HJURP,PHB2,DNAJB2,CENPF,CHCHD2,COX4I1,CDK13,DNAJB1,CNOT11,ARID1B,SUB1,MLX,MBD2,SSBP3,XPA,ZNF746,CTR9,AHCY,RBM3,ICE2,GLE1,DCAF8,LDB1,ZNF761,METTL22,APPL1,NPIPA1,RBM38,IRF5,HAUS8,RXRB,RPL36,SDHB,PAXX,MBIP,PCM1,COX7A2L,NLRC5,DTD1,RUVBL2,BTBD10,CCNB2,ECPAS,BCCIP,USP7,SART1,ARID2,TOR1AIP1,SLC2A1,LAGE3,ZNF416,RRAGC,LYN,PCBP1,ZNF121,OIP5,NRF1,PSMA6,ZNF473,KMT5C,BRPF3,ZNF302,ABRAXAS2,PIN1,PPME1,RPAP1,TARDBP,TOP1MT,STRAP,SPIDR,CTDSP2,ZNF583,PRPF19,KDM3B,ARHGAP17,MND1,BIRC3,POLR2G,ZNF780B,PPT1,PPIE,NUP155,DCLRE1C,VDAC1,TMEM201,SUGP1,AFDN,IDE,DHX16,RBL1,UBXN2B,STK38,UHRF2,CHMP4B,XRCC3,SPRYD4,H3F3A,CHID1,SMAD4,RAD51D,BCL2L12,SLC30A9,NIFK,CMAS,C19orf53,MCM10,AGO2,CDCA8,GTF3A,HMGN3,CDK11B,PAGR1,NCAPG,TUBGCP2,DNAJB9,POLR1B,ORC3,RBM15B,YTHDC1,PPAN,RHOA,RPRD1A,CSRP1,HMGN5,BTAF1,PRKDC,TOP3A,RANGAP1,PCGF1,API5,ZFR,DDX23,TRIM26,PDCD6,NEK1,L3MBTL3,NEIL3,BBX,E2F1,IMPDH1,RBPJ,TAF12,NR2F2,PGAM1,HIPK3,IFI16,TXN,NUP188,MAX,H2AFZ,PNISR,LUZP1,ADAM10,TSC22D3,CXXC1,CUL1,USP39,UBE2I,OAT,MYEF2,PARK7,GLMP,PA2G4,NOL11,FIZ1,ZNF200,TRA2B,TAF5L,SMARCE1,ZNF800,CDC5L,SRSF10,ZNF524,KLF10,NSUN2,SUPT20H,USP22,CBFB,RFC2,CLNS1A,EIF3A,PRIM1,ZMYM3,DOT1L,IWS1,HHEX,MKNK1,BRD2,KIF18B,RPS14,TPP2,LUC7L3,C1orf109,BTF3,PTPDC1,SLF1,CCDC59,ZMAT3,NMD3,B4GALT2,PTOV1,PRPF38B,RECQL,C9orf78,EWSR1,SCOC,POLR2K,GADD45G,PRKAA1,RRM1,TATDN3,CYCS,SUPT7L,PRPF39,ZNF79,ZNF518A,PSEN1,VPS25,YY1AP1,NPLOC4,CNOT3,WDR48,C12orf10,FAM192A,TMEM250,LHX8,EXOSC7,MSH2,MRPL40,CYC1,TNRC18,GID8,EIF5A,GCC2,PRIM2,ELL2,RDH10,USF3,ZNF574,RPS24,EXOSC9,ARID1A,ADRB2,PTTG1IP,FXR1,MAP2K2,CCT8,TWISTNB,PHF6,HMGN2,XRCC5,PFDN5,EPOP,RBMX,MED15,PIAS2,ARAP1,CEBPG,APPL2,CABIN1,GPI,NUDT3,CDKN2A,ZNF511,CYTIP,NDC1,ATXN3,TP53RK,RAF1,UROD,POMP,BCL2L1,C2orf49,EPM2A,DECR1,CCNA2,SIAH1,LPIN2,TAP2,TTC3,RNASEH2A,AQR,TP53BP2,ILKAP,CDK12,CFL1,SAP30,BRD4,DRAP1,NARF,VDAC2,ELP4,EDF1,PKMYT1,TRIM28,SUPT16H,EIF3K,ZNF282,RAD51C,CHMP4A,DSN1,HINT1,DGCR8,CERS6,SAFB,ATF6,BEND3,XRCC4,EYA2,PRPF4B,DEPDC1,MECP2,TKT,FAM76A,CBLL1,ARGLU1,SECISBP2,SPDL1,HMG20A,WWP2,EBP,RFWD3,CCNK,DNAJC8,ELP5,PTPN11,AXIN2,FEM1B,CARF,CITED2,MTX2,MSH6,PDLIM2,KAT2A,ANKRD37,RFXANK,BMS1,KIF11,COMMD4,KLF6,SPPL2B,FADD,CBX3,ZHX1,OAZ2,PPP1R11,DUSP11,DDX5,WDR62,TAF6,ESPL1,PURA,DEF6,DDB1,IPO4,FAM83G,RORB,POLA2,CCNC,ZNF76,LYRM4,KMT2E,HMGXB3,UBE2Q1,PTP4A3,BRIX1,COMMD5,MRPL19,ZNF696,SF3B2,DST,SIVA1,JAZF1,RPF2,GPATCH1,TCEA1,SLC35C2,CARMIL1,CARM1,SRPK2,DEAF1,LARS,SNRNP200,NCK1,LAP3,VHL,RIOX2,SREK1,KMT2C,OGFR,ASF1B,EIF4ENIF1,BRWD1,NIP7,U2SURP,PPM1G,SH3GLB2,CRCP,BAZ1B,STK11,ZNF268,CHEK2,CLU,VPS4A,DCAF5,UBE2D3,NSMCE4A,PPP1R12A,ZCCHC8,NACA,UBXN1,EPN1,RPL15,PM20D2,THRAP3,RGS2,QSOX2,TTF1,NUP205,PRPF18,LYAR,DTL,MED10,EI24,ZRANB1,MCPH1,CSNK1G3,POLR2I,NUDT4,SUGP2,RPL6,SYVN1,SLTM,DAPK3,MASTL,EVC2,UAP1,KLHL15,NFIL3,SIAH2,YWHAZ,CTSA,DNPH1,EHD4,SNRNP70,C11orf1,TOB1,TSEN15,N4BP2L2,ADNP2,TCF12,SNX27,PRKAB1,CHMP2A,MDH2,PMS2,SMARCA4,ORC1,CLCC1,MXD1,HNRNPA2B1,SAP130,RRN3,UBXN2A,CD3EAP,NVL,KIF14,EXOSC1,CS,UTP4,ZNF770,CSTF1,CHP1,POU2AF1,UBQLN4,NXT1,RNF25,SMU1,PCGF6,ATXN1,LSM8,GLO1,BICD2,OGDH,TOLLIP,MBD3,FANCE,RPS9,ALKBH6,PON2,VPS26C,HNRNPR,STAT6,ARNTL,ANP32E,FKBP5,MAPK1,TMEM33,CWC25,NAT14,DNAJC2,TRIP12,ZNF316,SHPRH,RAE1,SCYL1,NUP54,PAWR,MXD4,DCUN1D4,PIP4K2A,FASTKD3,FGFR3,MZT2A,KLHL20,KMT5A,PPIG,NABP2,H2AFY,ANP32A,FBL,STAT3,MICAL3,TXNL1,TGFB1,PPP1R9B,PHF20L1,DCAF6,TIMMDC1,HELB,PSPC1,MIER1,RFFL,RCOR1,PRMT2,CDK11A,TFEB,LEMD2,CTSL,UPF1,ZC3H7B,KMT2B,CENPT,ZMIZ1,HRAS,SLF2,TERF1,FGFR1OP,ADD1,KDM4A,MRPS15,MAP3K7CL,XIAP,DHX8,PPP1R16B,EDRF1,ANKRD23,MIS12,PABPC4,CALM2,CDK5,PSMD1,CIPC,NEK6,NSRP1,RABGAP1L,SRSF4,PDS5B,NUP153,SENP1,PCBP2,MLST8,PGAP2,PLK3,ZNF672,TMEM115,AATF,MCL1,TOPORS,SMC2,SLC50A1,STOML2,BRMS1,TRIM47,PWWP2B,WDR11,ZNF689,AXIN1,LIMK1,PRDX5,ATE1,FBXL3,TFDP2,E2F2,LONP2,AAAS,PFKP,DDX42,SSRP1,PHF23,TOP2B,EZH1,LMNA,RAVER2,DDRGK1,DDX56,EIF2S2,INTS7,MCM5,PHF14,ZNF326,RTCB,FOXN2,UBE2QL1,ETV3,RB1CC1,TSPYL4,PRRC2A,ZMYND11,TEX10,MYBL2,RPS10,SRSF5,CBFA2T2,MPG,ABCF1,MATR3,RHOB,NCDN,OSBPL11,POLR2J,CCDC86,DUSP3,SETD3,TEX30,CNOT6,SGF29,EGLN1,ZNF207,ZNF296,FAM208B,SARNP,TRERF1,IVNS1ABP,UBR2,CHD1L,TMEM97,RMI2,WDTC1,MYH9,CREBL2,RXYLT1,NUF2,ZNF267,SAFB2,PRKACA,TCF19,APP,CLUAP1,PRKD3,ATP2A2,SP100,ZKSCAN1,UTP18,DUT,DDA1,NUP107,ANAPC7,FAM76B,ATF2,RBM15,RNF169,DCTN1,SHOC2,PSRC1,INTS13,RNPS1,WBP2,ATP6V0A1,NUSAP1,CDCA2,DNAJA1,TAZ,FKBP3,DDX17,TAF2,CHCHD3,CDC16,HIPK2,RBMS1,FUS,PDXK,GEN1,ZBTB11,COIL,ZNF786,RPS2,TRAK1,JMJD6,GMCL1,UBE4A,AKT1S1,ETS1,WRB,ZNF92,PNO1,KRI1,FBXO3,CAPN2,ADD3,SUV39H2,NDUFB4,PPP1R8,PRDM4,DCP1A,GTSE1,GEMIN6,S100A6,HNRNPM,NUDC,PDPK1,PPP3CA,TNFAIP3,POLK,ZNF512,DDX39A,RPA1,ZNF862,ZNF180,KIF18A,KEAP1,POLE,TATDN2,PITX1,MAPK6,CAPN7,LRPPRC,PML,SLC25A19,HMGB2,WDR76,USF2,ANAPC4,FAF1,COX15,DDX47,THOC1,GPBP1L1,CSNK2A1,EBNA1BP2,GIT2,BIRC2,LIN9,PCNA,ZNF639,ETV6,TRMU,PIK3R2,XRCC2,ZFYVE27,MCMBP,MYBL1,CCAR1,SP3,METTL1,EXOSC6,PBXIP1,BAZ2A,TLK1,EZR,BRCA1,PRKRA,ANLN,RHEB,OPTN,EPB41,TIMM13,CDCA4,TONSL,NRM,ACTB,ZNF45,NUDT11,SINHCAF,GEMIN7,TMUB1,CTCF,RACGAP1,PPP3CB,RLF,ASXL2,CRLF3,SNRNP25,RB1,MED8,TIGAR,VMP1,CMTR2,PPIL2,TIMELESS,AFF1,MDFIC,MAML1,PREB,NQO2,MEMO1,UTP15,RTF1,UBE4B,NFATC2IP,ZNF174,SPATA33,PSMC4,SYNCRIP,PALB2,CDC27,SNAP23,TBPL1,PRMT7,ATP5F1A,RNF114,TIGD2,UGP2,FOXM1,XAB2,DYNLL1,SUMO2,COPE,HCFC1R1,DUSP22,RPAIN,COMMD8,RPL11,RAD23A,PDK2,ZBTB21,MDM2,STRBP,TNFAIP8,PDCD2,CORO1A,SAP30L,POC5,DVL2,RPL35,PSMA8,BTG2,TIGD5,DNAJC9,MTMR6,NFATC2,PRPF3,KDM1B,TXNL4A,USP36,RPSA,SRSF1,CLK3,ZNF700,MAFK,TIMM17A,PSMD3,ZNF436,DNAJC17,NCOA1,LTA4H,ZC3HC1,ZNF146,INTS2,CTDP1,CDC40,MIF4GD,CDT1,ARID5A,SMC6,NKRF,CSNK1A1,RMI1,WRNIP1,PTPN2,IRF4,STARD9,CWC27,SS18L1,DDX31,CENPM,PTGES3,CAMK2G,ZNF202,ZMYM5,PPWD1,FAM50B,CDKN2AIPNL,KPNA4,BIRC5,TFE3,SNAP29,CDCA7L,ACADM,UBE2C,CHMP7,ZNF496,NDUFB6,TMEM109,CCNB1,COMMD6,POLR3K,KIFC1,UTP25,SNUPN,CYB5RL,PARPBP,CDC25B,DNMT1,SEH1L,NOL12,USO1,AKT2,PBK,NOL8,ELOA,MKI67,MRNIP,DDX20,AMDHD2,AURKB,CCNF,SLC25A5,MAK16,RBM47,PSMD8,WDR4,EIF2D,PTPN7,RRS1,ARRB2,HDAC2,PWWP2A,PPIB,HSPH1,LIME1,CHTF18,KIF23,NOTCH2,PMF1,METTL3,JMY,NDUFAF6,MEX3C,KLF16,HDAC7,BDH1,GNAI2,EEF1D,TERF2,MORC3,PHF10,DDX28,ZNF84,SIGMAR1,PKM,CYFIP2,KDM3A,PATL1,SF3A2,PSMB3,FAS,ZNF777,SERTAD2,SERF2,ZFP92,DCK,CSNK1G1,ACLY,PPP3R1,DCAF11,TCOF1,YY1,PPP6R3,RNF14,CDK2,NRBP1,CABLES1,ZC3HAV1,DNMT3A,TRIP10,ZBTB37,RPS6KA1,SF3B1,SUZ12,URB2,MAGED1,OLA1,SDHA,SDE2,TERF2IP,PHC2,CRKL,CYHR1,APLP2,ZNF75D,KDM2A,UCHL5,TNPO2,CDKN1B,TALDO1,MRM2,GPX4,CDKN2AIP,RFC3,HMGN4,ERF,TAOK1,LYRM1,CUL3,SLBP,CDC23,H2AFV,GAR1,PSMB9,CENPU,PRDM11,SOCS7,NSA2,VEZF1,HSPA4,PPP2R5A,JAK1,TBL3,FAAP100,STAT1,H2AFX,TRIM32,PDCD11,ATMIN,CSNK1D,POLQ,POU3F2,NCOR2,R3HCC1L,TCF3,MRI1,BABAM1,BRAP,AGPAT3,MYNN,BLM,SPR,FOXO3,MAD2L2,PIP5K1C,GTF2F1,RBM17,MAT2B,RPL17,PTEN,CENPJ,PRC1,COPS7B,UPF2,CREB1,MAP3K14,CNOT6L,UBE2M,NCOA2,SMC4,TSHZ1,ZFP64,RNASEH2C,STRIP1,DENND1B,NEK7,NET1,WDR18,PARP4,ILF3,ANAPC2,TSR2,MARK2,PRDX1,POLR2A,NUCB1,PFDN4,HNRNPH3,MFAP1,TFDP1,NAXE,KHSRP,CCDC69,ASNA1,BRWD3,CPEB2,BYSL,S100PBP,DDX52,PTMS,IER2,NPHP4,NOP2,HNRNPAB,UBN1,NF1,ALKBH5,ZNF107,UBE2Z,KIF2C,SIRT2,AGFG1,TAF6L,UBQLN2,SNRPD3,USP48,BECN1,MAPK14,SNAPC4,CUTC,UBLCP1,MBD4,ZNF804A,CYREN,CMSS1,EIF4A3,IMPAD1,METTL14,PHTF1,SRI,AKR1B1,KHDC4,KIF22,ZBTB22,RP2,NFU1,TECR,OGG1,ARID4A,TIMM50,ELOF1,COPS8,FYTTD1,TDP1,TRIM8,DPM1,FOPNL,WDR82,SOX4,STK17B,DHX15,CHAF1A,GEMIN5,UBTF,PAF1,SPATA2,PQBP1,ATXN2L,COPS6,RPS26,PSMC1,RPS15,AGTRAP,ZNF768,CDIP1,CIB1,MED13L,TIA1,MEF2A,XPO7,PITHD1,SRRT,NFATC3,ZNF449,BANF1,BUD31,ZNF335,KIFAP3,BCL2,YBX1,KNTC1,UBE3C,ZNF189,HP1BP3,CIC,OXR1,PSMA1,SEPT7,ISG15,CAND1,TSC1,NAP1L1,RBM25,NSMF,CDCA5,ODF2,NUP62,ZFP90,NAA20,RBBP4,HNRNPDL,MZT2B,SMARCD1,ZBTB24,MBD1,ASH1L,FAM92A,MPHOSPH8,CHERP,WDYHV1,HNRNPUL2,PLAGL2,NSD3,IRF3,CHD1,MEAF6,ANKRD28,ANKLE1,BABAM2,AKAP8,PARL,CHTOP,ABI1,HTRA2,RLIM,MOSPD1,ACSL5,FAM172A,ZNF500,PSMB7,TOR1AIP2,ERBIN,NDUFB1,BUD13,EIF3G,RAD54B,ZNF317,DAP3,TAB2,CHCHD1,TULP3,GADD45B,USP11,AKNA,SMURF1,CBX4,MIF,CASP6,EYA1,CDK2AP2,MRPS26,DBF4,LETMD1,KLF13,FBXO5,CTNNBL1,PELO,BRD7,SLC25A1,SAMD4B,GINS1,CSNK1G2,TELO2,GTF3C6,HMGN1,NASP,ASPM,POLR3GL,MEN1,ATP5MF,ZNF407,SYMPK,SNRPA,MAPK3,HSPA1B,CNOT9,ATAD2,PLAA,OSBPL8,ZNF330,ZRANB2,MBD6,SRSF3,IDH3B,TATDN1 |
| 6.516e-73 | -166.21 | cellular metabolic process | biological process | GO:0044237 | 9016 | 1790 | 17256 | 2622 |
ZBTB10,HEXB,TGOLN2,LACTB2,CCNL2,RBM4,ZNF275,FBXO22,EEF2K,RPL23A,USF1,RAD23B,MECR,DNM2,UPRT,CRY2,ECD,RNF26,ZNRD1,TIPARP,ANKRD9,MGAT5,FTSJ3,MRPL57,USP34,ERCC1,ZNF559,NRAS,GABPA,EHMT1,HNRNPF,WDHD1,MIER2,DIDO1,MCM2,ARF4,GINS4,SMAD2,RAD18,RPS27A,MYO18A,OGT,COX5A,RNASEL,KLHL42,SMAD1,CHPF2,ZNF75A,OAZ1,SMNDC1,SLC25A33,ZNF720,HIVEP3,CLSPN,GGA1,MUM1,TRIO,DHX9,RAB23,KCTD17,EIF2AK4,PDCD7,PSMD9,APH1B,PARN,CDC73,ATG4A,TFAP4,PDXP,SMC3,RNFT1,FBXO7,EFTUD2,GEMIN4,MRPL21,CPSF4,NUP85,PABPC1,PHKG2,NSUN4,PPA1,LUC7L2,SRSF11,EIF3L,AGGF1,FOXK1,MAPKAPK3,MTA2,MTFR2,SF3B6,ERO1A,TYW1,GTPBP4,USP10,BCLAF1,MRPL16,ELK1,EIF4H,RDH11,FNTA,KPNA1,ETS2,TYW5,WIPI2,ZNF830,CFAP20,ACSF2,NUP58,MRPL3,ALS2,TRIM41,KARS,NQO1,PTTG1,VTI1A,STARD7,INO80E,SLC35B2,GLRX3,RCOR3,LCLAT1,CPNE3,ABHD16A,RBM23,FBXL6,ZNF420,MTA1,UBA5,GMEB1,NABP1,NSFL1C,INTS12,ZNF226,GPD1L,ZC3H3,RPRD1B,CGGBP1,PDCL3,CPNE1,ULK3,SEC61B,POLR2L,EID1,KAT7,IDH3A,CRNKL1,RPL38,E2F3,POLR2D,PFKFB3,MEF2D,RAB1A,MAT2A,PPP2CA,ALDH3B1,LSM6,NSMCE2,CAMKMT,RNF38,DMWD,SNRPG,PPP5C,USP13,COMMD10,ZNF445,SRSF6,ZFP91,TRMT6,CCM2,HABP4,ABHD14B,ATG2B,IP6K2,ATP5F1B,WDR5,PMVK,NEXMIF,RRP36,NEIL2,TUT4,PPP1R3B,GOLM1,RPA2,ZBTB45,PSMD2,CLIC4,ITGB8,COQ4,HUWE1,ZNF260,NAA50,LTN1,KANSL2,UBE3B,ST8SIA2,ZNF710,GTF2H2,FBXL19,RPL22L1,MED22,SPTAN1,DDX24,USP42,MRS2,LDHA,PICALM,UTP20,SLC19A1,MAGT1,GPS2,PARG,ACOX1,DBI,AEN,CD81,PARP10,WDR45B,THAP5,TRIM11,YTHDC2,RBM8A,SND1,RUFY1,FANCI,PAPOLA,ZER1,KRR1,CREM,TET3,FANCL,RAB8A,NUP210,NT5DC1,GLIS2,IL6ST,INTS1,SLC44A1,POP7,NOC2L,EIF5,MTPN,ASB6,RYBP,PLK1,RPP25,PTPN18,RBX1,APH1A,RAD51AP1,SNRPB,CDC6,UBE2V1,PBRM1,EAF2,UTP3,KRTCAP2,ODC1,LUC7L,USP21,ALG3,TRIM4,AGPAT2,CHD3,ZNF367,E2F4,ARRDC1,PRPF4,KPNA2,DVL1,CLN3,BEND6,FAM208A,NGLY1,POT1,ZNF564,FUBP1,RMND5A,CTU2,ZCCHC9,PHB2,CENPF,SDC2,LAMTOR3,CHCHD2,COX4I1,ADCK5,CDK13,RAB6A,CNOT11,RSAD1,ARID1B,C1GALT1,SUB1,MLX,UBE2Q2,CCP110,MBD2,SSBP3,XPA,ZNF746,CTR9,AHCY,ICE2,RBM3,MRPL48,LRSAM1,HDHD2,NTPCR,ABHD2,DCAF8,ACSL3,LDB1,AMD1,MAP4K3,ZNF761,METTL22,ARMC8,STYXL1,RBM38,NMT2,IRF5,RMC1,RPL36,RXRB,SDHB,PAXX,MBIP,GALNT2,ORMDL2,COX7A2L,ZDHHC7,DTD1,RUVBL2,ECPAS,BCCIP,USP7,SART1,TRAF7,RPLP2,SUCLG1,ARID2,NDUFAF2,SLC2A1,LAGE3,ZNF416,ZFYVE21,RRAGC,ATP6V1B2,LYN,PCBP1,ZNF121,MRPL50,VAV1,NRF1,PSMA6,ZNF473,KMT5C,BRPF3,ZNF302,ABRAXAS2,PIN1,PPME1,RPAP1,TARDBP,LMAN1,TOP1MT,AHCYL1,STRAP,SPIDR,CTDSP2,SPSB3,ZNF583,PRPF19,SNX25,PPIF,KDM3B,MND1,BIRC3,POLR2G,ZNF780B,PPT1,RAB7A,PPIE,NUP155,DCLRE1C,CHMP2B,VDAC1,MRPS14,EIF3H,SUGP1,IDE,DHX16,RBL1,UBXN2B,FASTK,STK38,UHRF2,CHMP4B,XRCC3,H3F3A,CHID1,SMAD4,RAD51D,SLC30A9,NADSYN1,NIFK,CMAS,MCM10,MTERF1,KLHL21,AGO2,TMX3,CDCA8,GTF3A,ARF1,CDK11B,PAGR1,SCYL2,DNAJB9,HERC3,GTPBP3,CTSS,POLR1B,ORC3,RNLS,RNF5,RBM15B,YTHDC1,ACP2,RHOA,RPRD1A,HMGN5,PRKDC,TUFM,TOP3A,RANGAP1,PNPLA8,PCGF1,HAGH,DDX23,NEK1,L3MBTL3,NEIL3,CTBS,BBX,E2F1,IMPDH1,USP20,RBPJ,TAF12,NR2F2,PGAM1,HIPK3,IFI16,TXN,NUP188,MAX,PDCD6IP,GXYLT1,ADAM10,PRKCSH,CXXC1,CUL1,USP39,NANS,GYG1,UBE2I,OAT,MYEF2,PARK7,ASPHD2,PA2G4,MTFR1L,NOL11,FIZ1,RAB4A,ZNF200,TRA2B,FBXW2,SUCLG2,AP2B1,CISD2,TAF5L,SLC26A2,MARCH2,ZNF800,CDC5L,SRSF10,ZNF524,KLF10,NSUN2,SUPT20H,USP22,CBFB,RFC2,CLNS1A,EIF3A,PRIM1,DOT1L,IWS1,MAP3K4,HHEX,MKNK1,BRD2,RPS14,TPP2,LUC7L3,MRPL27,BTF3,PTPDC1,SLF1,CCDC59,B4GALT2,PTOV1,PRPF38B,RECQL,COX5B,EWSR1,DHPS,POLR2K,GSPT2,PRKAA1,RRM1,TATDN3,B4GALT1,CYCS,SUPT7L,PRPF39,ZNF79,ZNF518A,PSEN1,TMEM165,PDXDC1,VPS25,NDUFS7,YY1AP1,CNOT3,NPLOC4,WDR48,RPN1,LHX8,EXOSC7,KLHL5,ZNRF2,PPP4R1,MSH2,DAPK1,TPST1,PIGG,FBXL7,MRPL40,CYC1,MRM3,APOL1,FDFT1,SOCS5,EIF5A,PIGT,PRIM2,CPQ,ELL2,COQ8A,RDH10,USF3,MFNG,ZNF574,RPS24,EXOSC9,ARID1A,ADRB2,MTR,MAP2K2,TWISTNB,PHF6,PI4K2A,XRCC5,DERL1,CAT,MTHFD2,GOLGA2,EPOP,RBMX,MED15,PIAS2,USP32,CEBPG,SAMD8,SMPD4,GPI,NUDT3,ZNF511,NDC1,ATXN3,TP53RK,RAB11B,RAF1,UROD,C2orf49,CD320,SPINDOC,NUDT19,DECR1,CCNA2,SIAH1,MTMR4,ADCY9,LPIN2,SOCS6,MRPS27,TTC3,RNASEH2A,AQR,ILKAP,CDK12,CFL1,SAP30,BRD4,DRAP1,ELP4,EDF1,PKMYT1,ASB13,ERC1,SERP1,TRIM28,SUPT16H,EIF3K,ANKZF1,ZNF282,RAD51C,CHMP4A,HINT1,DDOST,RAB24,DGCR8,CERS6,SAFB,FTSJ1,ATF6,BEND3,XRCC4,EYA2,PRPF4B,NDUFS1,DEPDC1,B4GALT5,MANBA,MECP2,TKT,CBLL1,ARGLU1,SECISBP2,POFUT1,HMG20A,WWP2,RFWD3,CCNK,DNAJC8,NDUFA2,ELP5,FUT8,PTPN11,AXIN2,MRPL54,FEM1B,RPL19,CARF,CITED2,NDUFA3,MSH6,KAT2A,LONRF3,RFXANK,ADSL,FBXO9,BMS1,KCNQ1,OTUD3,ARSK,GUF1,KLF6,COMMD4,SPPL2B,SH3GLB1,CBX3,RPL32,ZHX1,OAZ2,PPP1R11,DUSP11,DDX5,NDUFS5,WDR62,WDR91,TAF6,PURA,DDB1,RORB,CCNC,POLA2,ZNF76,PIGM,KMT2E,UQCR10,PHRF1,HMGXB3,PTP4A3,UBE2Q1,COMMD5,MAP1LC3B,ATP5PF,MRPL19,ZNF696,SF3B2,PCYOX1L,CDC42,GOT2,RAB35,JAZF1,HADHB,RPF2,GPATCH1,TCEA1,SLC35C2,CARMIL1,DRAM2,CARM1,SRPK2,WDR41,DEAF1,LARS,SNRNP200,NCK1,VHL,RIOX2,SREK1,SUMF2,KMT2C,PRPSAP1,MPC1,ASF1B,RPL37,MAN2A2,BRWD1,U2SURP,PPM1G,CRCP,CAB39,BAZ1B,STK11,ZNF268,CHEK2,CLU,VPS4A,CHPT1,MRPL13,DCAF5,CAPN1,UBE2D3,NSMCE4A,PPP1R2,PPP1R12A,ZCCHC8,GORASP1,NACA,UBXN1,PCSK7,RPL15,PM20D2,THRAP3,TTF1,NUP205,PRPF18,CHKA,LYAR,DTL,MED10,PYURF,EI24,ZRANB1,CSNK1G3,ATP5IF1,POLR2I,ERLIN1,NUDT4,SUGP2,RPL6,GBA,SYVN1,EIF2A,VKORC1,CCDC71L,SLTM,DAPK3,MASTL,UAP1,KLHL15,NFIL3,SIAH2,SLC16A1,FN3KRP,CTSA,DNPH1,SNRNP70,TSEN15,ADNP2,TCF12,PRKAB1,CHMP2A,MDH2,PMS2,UCK2,SMARCA4,UCK1,ORC1,EXT2,MXD1,USP5,HNRNPA2B1,SAP130,RRN3,UBXN2A,IARS,CD3EAP,KIF14,EXOSC1,PPP6C,CS,UTP4,ZNF770,CSTF1,CHP1,POU2AF1,UBQLN4,HPDL,PGGT1B,RNF25,METTL2A,SMU1,PCGF6,ATXN1,LSM8,GLO1,OGDH,EDEM2,TOLLIP,FANCE,MBD3,RPS9,PDHX,PON2,DUS3L,HNRNPR,STAT6,ARNTL,FKBP5,BRD9,MAPK1,ABCA1,CWC25,PDF,NAT14,DNAJC2,GCLM,TRIP12,ZNF316,SHPRH,RAE1,SCYL1,NUP54,PAWR,MXD4,DCUN1D4,PIP4K2A,GFM2,SPPL2A,FASTKD3,FGFR3,GRK2,KLHL20,KMT5A,PPIG,RRBP1,NABP2,DUS2,ANP32A,ATG13,NDUFS8,FBL,ERI3,STAT3,SLC35A1,MYO5A,AMPD2,B3GALT6,TGFB1,ELOVL5,PPP1R9B,DCAF6,HEMK1,HELB,PSPC1,MIER1,NADK2,RFFL,RCOR1,PRMT2,CDK11A,TFEB,MTMR3,CTSL,UPF1,ZC3H7B,DTX4,KMT2B,ACAT1,ZMIZ1,PLOD3,HRAS,TERF1,SLF2,RAB14,FGFR1OP,ADD1,KDM4A,MRPS15,MAP3K7CL,PIGQ,AGPAT1,XIAP,DHX8,GLUD1,EDRF1,PABPC4,CDK5,PSMD1,CIPC,NEK6,NSRP1,SRSF4,PDS5B,FNIP2,NUP153,SENP1,KCNAB2,PCBP2,PGAP2,PLK3,ZNF672,TMEM115,MRPL43,TOPORS,DCUN1D5,ICMT,PLEKHF2,STOML2,BRMS1,ZNF689,AXIN1,LIMK1,PRDX5,ATE1,VIPAS39,MLYCD,ST3GAL2,SMG9,FBXL3,TFDP2,E2F2,LONP2,AAAS,PFKP,DDX42,SSRP1,NDUFV2,MRPL9,MRPS2,PHF23,CERK,TOP2B,EZH1,ZNRF3,MCTS1,RAVER2,DDRGK1,GNS,DDX56,EIF2S2,INTS7,INPP5A,MCM5,RTCB,ZNF326,FOXN2,CARS2,UBE2QL1,NAGPA,ETV3,RB1CC1,DHX29,PGS1,ZMYND11,MAN1B1,TEX10,MYBL2,RPS10,ARMT1,SRSF5,CBFA2T2,MPG,ABCF1,CYB5A,PTPRF,SCARB2,POLR2J,DUSP3,CSK,SETD3,TEX30,PTAR1,MDH1,CNOT6,PLPP6,HEXA,SGF29,SNX14,RNF139,EGLN1,ZNF296,ABCA3,SARNP,TRERF1,IVNS1ABP,UBR2,CHD1L,RMI2,WDTC1,CREBL2,RXYLT1,NIT2,ZNF267,EFL1,SAFB2,PRKACA,TCF19,STAM,APP,KTN1,ANKIB1,PRKD3,SP100,ZKSCAN1,UTP18,GRSF1,DUT,DDA1,NUP107,ANAPC7,RNF19A,MAVS,ATF2,RBM15,CLN6,RNF169,ADCY7,ENPP4,INTS13,MAP4K4,RNPS1,WBP2,ATP6V0A1,NDUFA7,TAZ,FKBP3,DDX17,TAF2,CHCHD3,PEX5,CDC16,HIPK2,NT5C3B,RPLP1,RBMS1,MBOAT1,PDXK,FUS,GEN1,ZBTB11,LRP8,GALK1,ZNF786,RPS2,TRAK1,JMJD6,UBE4A,ETS1,PLPP5,PNO1,ZNF92,KRI1,FBXO3,CAPN2,ERH,SUV39H2,GATC,NDUFB4,PPP1R8,PRDM4,DCP1A,GTSE1,GEMIN6,TTLL12,HNRNPM,LYPLA2,IMPA2,LDHB,PDPK1,PPP3CA,TK1,GUK1,TNFAIP3,GALC,POLK,ZNF512,MRPS10,MTMR12,DDX39A,PDE3B,RPA1,ZNF862,ZNF180,KEAP1,POLE,TATDN2,PITX1,MAPK6,LRPPRC,PML,SLC25A19,HMGB2,PSAP,USF2,ANAPC4,FAF1,SNAPIN,SRM,COX15,DDX47,AGRN,THOC1,GPBP1L1,GNPDA1,PPP1R15B,MCCC1,CSNK2A1,EBNA1BP2,CDIPT,BIRC2,LIN9,ABL2,PCNA,ZNF639,ETV6,TRMU,PIK3R2,XRCC2,PPCDC,MCMBP,MYBL1,MRPL32,CCAR1,ABCC5,PTPRK,CDC37,SP3,METTL1,EXOSC6,HARS,BAZ2A,TLK1,MRPL12,GMFB,EZR,BRCA1,ESYT1,PRKRA,OPTN,TBC1D17,TONSL,SOCS4,QRSL1,ACTB,DHFR2,OSGEPL1,ZNF45,NUDT11,NAA60,GEMIN7,SEPHS2,TMUB1,CTCF,ASAH1,PPP3CB,B4GALT4,RLF,ASXL2,SNRNP25,RB1,NUS1,MED8,TIGAR,VMP1,CMTR2,PPIL2,SLC27A4,TIMELESS,MDFIC,MAML1,ALDH18A1,PREB,ABCC1,AACS,NQO2,UTP15,KRAS,EIF2AK1,RTF1,UBE4B,NFATC2IP,LY6E,EIF4G2,ZDHHC3,ZNF174,PSMC4,SYNCRIP,PALB2,CDC27,PRPS2,TBPL1,PRMT7,ATP5F1A,RNF114,KCTD7,NDUFA5,CYLD,UGP2,FOXM1,MRPL39,DYNLL1,XAB2,SUMO2,ZADH2,GGPS1,DUSP22,RPAIN,COMMD8,RPL11,RAD23A,SEC11A,CSDE1,PDK2,ZBTB21,MDM2,DUS4L,MRPL34,MINPP1,SAP30L,GM2A,DVL2,RPL29,RPL35,PSMA8,COQ10B,BTG2,CPOX,MTMR6,NFATC2,PRPF3,KDM1B,TXNL4A,USP36,RPSA,SRSF1,MRPL2,DNAJC10,ATP1A1,CLK3,ZNF700,MAFK,PSMD3,TOMM6,NDUFA11,ZNF436,DNAJC17,NCOA1,LTA4H,AP2S1,SLC25A39,USP53,ZC3HC1,INTS2,CTDP1,CDC40,RRP15,DAP,CDT1,GNE,ARID5A,SMC6,NKRF,SUMF1,CHAC2,GGA2,CSNK1A1,RMI1,TFRC,WRNIP1,PTPN2,IRF4,GSTK1,NDUFV1,CWC27,SS18L1,ABCD1,DDX31,PTGES3,CAMK2G,CNTN5,ZNF202,ZMYM5,PPWD1,NEU1,FBXO41,GOLGA7,BIRC5,TFE3,SNAP29,CDCA7L,FAM126A,SPCS3,ACADM,RPS6KC1,UBE2C,SAT2,GCSH,ZNF496,PPCS,NDUFB6,ZDHHC8,NHLRC3,CCNB1,EIF1B,COMMD6,SLC20A1,POLR3K,UTP25,SNUPN,PARPBP,RNASEK,CDC25B,MAST2,SPTSSA,DNMT1,SEH1L,ATG9A,AKT2,PBK,NOL8,ELOA,MRNIP,DDX20,GALNT7,AMDHD2,AURKB,CCNF,MCFD2,MAK16,RBM47,STT3A,PSMD8,WDR4,EIF2D,PTPN7,ITGB1,DHTKD1,UQCRH,RRS1,ARRB2,ZNF598,HDAC2,DDX58,WSB2,PPIB,LIME1,MUT,GMFG,CHTF18,ADO,NDUFA4,MAN2B1,PMF1,NOTCH2,METTL3,JMY,NDUFS4,FKBP1A,RNF121,KLF16,HDAC7,ATIC,DAD1,BDH1,CTPS1,ATP6V0A2,PCYT2,RNF135,PIKFYVE,LPCAT1,EEF1D,TERF2,MORC3,PHF10,DDX28,ZNF84,NOA1,PIP4K2C,DCTD,PKM,TOMM40,KDM3A,PATL1,SF3A2,PSMB3,ADSS,EPRS,ZNF777,SERTAD2,ZFP92,CSNK1G1,QARS,DCK,ACLY,DCAF11,LPCAT4,PPP3R1,VCPIP1,YY1,MAP3K5,RNF14,CDK2,NRBP1,ZC3HAV1,DNMT3A,RWDD1,ZBTB37,RPS6KA1,SF3B1,SUZ12,EIF3D,RAC1,OLA1,KLHL18,ADPGK,SDHA,SDE2,TERF2IP,CRKL,FLAD1,APLP2,ZNF75D,SHC1,KDM2A,UCHL5,TALDO1,NAA35,MRM2,GPX4,RFC3,ERF,TAOK1,CUL3,SLBP,KIAA1586,GALK2,CDC23,POLG2,PSMB9,GAR1,DHX57,CENPU,PRDM11,SOCS7,NSA2,VEZF1,JAK1,PPP2R5A,MRPL55,ACYP1,TBL3,FAAP100,GUCY1B1,H2AFX,STAT1,SEL1L,PPA2,TRIM32,B4GALT3,PDCD11,CSNK1D,ATMIN,POLQ,POU3F2,OTUD5,NCOR2,TWNK,TCF3,MRI1,BABAM1,CDCA3,SLC25A12,BRAP,AGPAT3,MYNN,SDF2L1,BLM,SPR,RAB11A,FOXO3,MAD2L2,PIP5K1C,GTF2F1,RBM17,MAT2B,RPL17,PTEN,CRAT,UPF2,COPS7B,CNOT6L,OSTC,CREB1,MAP3K14,UBE2M,PACS2,NCOA2,TSHZ1,ZFP64,RNASEH2C,NEK7,TRIR,WDR18,PARP4,ILF3,RPL8,TBRG4,ANAPC2,RHOT1,RPL27A,MARK2,TSR2,ECH1,PRDX1,POLR2A,FBXO21,NUCB1,SGSH,HGS,ATP5MC3,TTLL4,PRDX3,HNRNPH3,TFDP1,NAXE,KHSRP,CPEB2,BYSL,ESYT2,DDX52,MIB2,ADA2,PTMS,IER2,UBE2E2,NOP2,NF1,DCAF15,ALKBH5,MOGS,DNAJC24,ZNF107,UBE2Z,SLC29A1,TAF6L,SIRT2,SNRPD3,UBQLN2,USP48,FKBP2,MAPK14,BECN1,SNAPC4,RNF103,EDC3,BCAT2,UBLCP1,MBD4,CYREN,THADA,EIF4A3,METTL14,ATG3,IMPAD1,DPYSL2,PHTF1,AKR1B1,KHDC4,KIF22,NDUFB9,ZBTB22,JOSD1,NFU1,TECR,OGG1,ARID4A,FGFR1OP2,TIMM50,ELOF1,COPS8,TDP1,TRIM8,DPM1,RRM2,WDR82,SOX4,STK17B,DHX15,CHAF1A,ABHD5,PAF1,GEMIN5,UBTF,UEVLD,PQBP1,IARS2,GALNT10,ROCK1,COPS6,RPS26,PSMC1,STARD3NL,RPS15,PIGN,ZNF768,UFC1,CIB1,MED13L,MEF2A,EPHX2,SRRT,RHBDD1,NFATC3,ZNF449,ZNF335,BUD31,BCL2,GLTP,YBX1,ACAD8,UBE3C,N4BP2,ZNF189,ALDH9A1,VOPP1,TSTA3,CIC,PSMA1,ISG15,CAND1,GNAS,NAP1L1,RBM25,CDCA5,TRMT10B,NUP62,ZFP90,RBBP4,NANP,NAA20,NIPSNAP2,HNRNPDL,PTDSS1,PDSS2,ZBTB24,MBD1,MMACHC,TOMM20,ASH1L,MPHOSPH8,GNPNAT1,CHERP,WDYHV1,PLAGL2,NSD3,CHKB,IRF3,CHD1,MEAF6,PAIP1,FARSA,ANKLE1,BABAM2,AKAP8,RPN2,CHTOP,PDIA6,ABI1,TMEM14C,SCYL3,HTRA2,RLIM,ACSL5,CGAS,ZNF500,PSMB7,NLN,NDUFB1,BUD13,EIF3G,BTBD1,RAD54B,DAP3,ZNF317,TAB2,CHCHD1,CANT1,SCARB1,USP11,AKNA,SMURF1,PPP2R2D,CBX4,MIF,CDS2,SH2D3A,MRPL42,EYA1,MRPS26,DBF4,KLF13,HDDC2,MAN1A1,GART,CTNNBL1,PELO,BRD7,MRPL11,SLC25A1,SAMD4B,GINS1,ZDHHC18,CSNK1G2,TELO2,GTF3C6,ADAM17,HMGN1,NASP,PRKAR1B,POLR3GL,WDR81,MEN1,ATP5MF,ZNF407,SYMPK,SNRPA,TARS,MAPK3,MFN2,HSPA1B,CNOT9,ATAD2,PLAA,OSBPL8,COX8A,KBTBD7,ZRANB2,SRSF3,MBD6,TATDN1,IDH3B,TYW1B |
| 1.960e-68 | -155.90 | PILON_KLF1_TARGETS_DN | MSigDB lists | PILON_KLF1_TARGETS_DN | 1855 | 558 | 17377 | 2626 |
RAB14,TMED7,HECA,MRPS15,XIAP,CMTM6,FBXO22,THAP4,RABGAP1L,TTC9C,AP1M1,FNIP2,MOB1A,LRRC59,SENP1,KCNAB2,NRAS,EHMT1,WDHD1,MCL1,NUTF2,RAB22A,PLEKHF2,AHNAK,SMAD2,RAD18,AXIN1,COX5A,E2F2,SMNDC1,ANXA11,KIAA0100,MRPS2,MUM1,COPB2,FBRS,MCTS1,TFAP4,PDXP,INTS7,EFTUD2,FOXN2,SRSF11,CYFIP1,IFRD1,ETV3,FOXK1,MAPKAPK3,PGS1,TEX10,ABCF1,DTWD1,SCARB2,OSBPL11,FNTA,MDH1,NDE1,TRIM41,SARNP,IVNS1ABP,ACTR3,STARD7,C5orf30,NUF2,SAFB2,C19orf48,STMN1,TCF19,STAM,ANKIB1,REPS1,CPNE3,KIAA1147,RAB21,PRKD3,DUT,DDA1,GMEB1,INTS12,SEPT11,FAM76B,ATF2,CGGBP1,ADCY7,EID1,IDH3A,RNPS1,NUSAP1,MEF2D,RAB1A,FKBP3,ALDH3B1,LSM6,RNF38,RBMS1,PDXK,PPP5C,COIL,MZT1,SRSF6,TRMT6,CCM2,GMCL1,ATG2B,WDR5,IFT27,ETS1,FBXO3,RPA2,GOLM1,ADD3,PPP1R8,NAA50,DCP1A,GEMIN6,LTN1,TPCN1,IMPA2,HNRNPM,PDPK1,MOB4,PPP3CA,TACC1,USP42,DDX39A,PDE3B,TTC33,SH3BP5,SLC19A1,POLE,MAGT1,PARG,CAPN7,DBI,FAM3C,C4orf46,HMGB2,WDR76,ANAPC4,GPATCH4,SNAPIN,COX15,FAM129A,TRIM11,RBM8A,ENSA,EBNA1BP2,CDC42SE2,RUFY1,GIT2,ATPAF1,SSR1,KRR1,NUP210,NT5DC1,ETV6,TXLNA,NOC2L,MTPN,VPS13B,RYBP,SP3,PTPN18,RAD51AP1,SNRPB,PSMG1,CKAP2L,UBE2V1,ANLN,STX16,LUC7L,RHEB,NECAP2,CDCA4,AGPAT2,BCL7C,ADAM9,CLN3,NGLY1,MYL12B,CCDC137,SEPHS2,CTU2,ZCCHC9,PHB2,CTCF,ASAH1,RACGAP1,PPP3CB,DOCK11,ARID1B,SUB1,TNS3,NUS1,RINL,TIMELESS,AFF1,MAML1,HDHD2,ABCC1,UTP15,KRAS,RTF1,LY6E,ICAM2,ARMC8,IRF5,ANKRD46,PSMC4,GALNT2,TMEM168,PRPS2,FAM122A,USP7,NDUFA5,CYLD,UGP2,ARID2,FAM207A,MRPL39,TOR1AIP1,TMX4,TM9SF3,COMMD8,TMEM69,VAV1,STRBP,CORO1A,METTL9,LMAN1,STRAP,GM2A,PRPF19,ARHGAP17,BIRC3,PPT1,MTMR6,PRPF3,CHMP2B,VDAC1,TXNL4A,TMEM201,DNAJC10,IDE,RBL1,STK38,CEP55,SMAD4,CDC40,TMX3,CDK11B,AP3S1,BZW2,PTPN2,SLC35B4,ABCD1,POLR1B,PTGES3,CAMK2G,RPAP3,RPRD1A,MLEC,SNX2,TOP3A,PNPLA8,API5,KPNA4,ACADM,RBPJ,SPCS3,HIPK3,PDCD6IP,GXYLT1,ADAM10,TMEM109,USP39,CUL1,GYG1,POLR3K,ABHD14A,CNPY4,TRA2B,FBXW2,SPTSSA,PLCL2,SMARCE1,DNMT1,CDC5L,NOL12,KLF10,PBK,LACTB,GALNT7,CBFB,SLC25A5,PRIM1,ANKRD10,HHEX,BRD2,TMED10,RRS1,ARRB2,SVIP,RECQL,EWSR1,MAPRE1,ADO,ACAP1,CYCS,NOTCH2,TMEM165,CFLAR,FKBP1A,RPN1,KLHL5,LRRC8D,SNX18,ZNRF2,ATIC,PPP4R1,MSH2,TNRC18,LPCAT1,MORC3,PRIM2,PIGT,WDR1,EMB,MFNG,ZNF574,KCTD20,FAM133B,DCTD,CAPZA2,ARID1A,CYFIP2,C9orf40,GOSR1,CCT8,TWISTNB,SEC31A,ADSS,SERTAD2,TTC13,RBMX,DCK,ACLY,VCPIP1,TCOF1,MAP3K5,YY1,RNF14,CYTIP,RWDD1,CKLF,SF3B1,RPS6KA1,CAST,ADPGK,MTMR4,RALB,UCHL5,SOCS6,TP53BP2,AQR,NAA35,SAP30,ANKLE2,MAPRE2,SLBP,PKMYT1,GAR1,SHCBP1,TRIM28,SOCS7,VEZF1,HSPA4,PPP2R5A,CERS6,TBL3,SAFB,PPA2,STAT1,NCLN,CSNK1D,DYNC1LI2,NCOR2,MANBA,CBLL1,RFWD3,RPL17,PTEN,FUT8,PRC1,BTF3L4,FEM1B,TAGLN2,CNOT6L,NCOA2,MSH6,TSHZ1,RNASEH2C,NEK7,DENND1B,ILF3,RABIF,RHOT1,KLF6,TSR2,CBX3,MYO1F,YIF1A,C1orf131,MFAP1,TFDP1,DDX5,DUSP11,NDUFS5,DEF6,VPS29,ESYT2,SKA3,HNRNPAB,PLXNC1,ST13,KIF2C,USP48,BRIX1,MAPK14,MRPL19,RAP1A,CDC42,EIF4A3,ATG3,DPYSL2,METTL14,IMPAD1,ZNHIT6,RAB35,RCSD1,HADHB,AKR1B1,RP2,CNNM3,FGFR1OP2,ELOF1,SRPK2,NCK1,LAP3,ARHGDIB,PITPNB,SOX4,PRPSAP1,STK17B,DHX15,ABHD5,MAN2A2,EIF4ENIF1,NIP7,BAZ1B,CAB39,TSTD2,UBE2D3,NSMCE4A,PPP1R2,ZCCHC8,CIB1,MED13L,THRAP3,RGS2,XPO7,NUP205,DTL,NFATC3,CSNK1G3,HP1BP3,ERLIN1,OXR1,SYVN1,EIF2A,ARHGAP15,NAP1L1,PITPNA,NAA20,PTDSS1,TSEN15,ZBTB24,TMEM106C,MBD1,CORO7,HNRNPUL2,UCK2,TWF2,C2orf68,ANKRD28,CCDC50,EXOSC1,PARL,CHTOP,PDIA6,ABI1,SCYL3,EBAG9,ACSL5,FAM172A,SELPLG,PCGF6,WIPF1,RPS9,BTBD1,TAB2,HNRNPR,ARNTL,PROSER1,ANP32E,AKNA,BRD9,MAPK1,TSPAN5,CBX4,SRGN,DBF4,NUP54,PIP4K2A,XPR1,SPPL2A,GART,ZDHHC13,ANP32A,BRD7,H2AFY,CLDND1,TTC17,LDLRAD3,MRPL11,GINS1,TGFB1,GTF3C6,ZDHHC18,ELOVL5,HMGN1,ADAM17,NASP,FAM49B,PPP1R21,RFFL,RCOR1,ZNF407,UPF1,ELMO1,ZNF330,DTX4,ACAT1,MBD6,SRSF3,ZMIZ1,TERF1,ZSWIM6 |
| 2.442e-68 | -155.68 | cytoplasm | cellular component | GO:0005737 | 11448 | 2089 | 18223 | 2701 |
HECA,ABCC10,HEXB,TGOLN2,SYNRG,FBXO22,EEF2K,RAD23B,DNM2,USP34,ERCC1,NRAS,KIF15,HNRNPF,WDHD1,MIER2,DIDO1,MCM2,RAB22A,MID1IP1,SMAD2,RPS27A,MYO18A,OGT,MPV17,COX5A,KLHL42,SMAD1,ANXA11,SLC25A33,GGA1,SEC61G,CCZ1,MUM1,TRIO,RAB23,KCTD17,HAUS4,EIF2AK4,APH1B,PARN,CDC73,MYL6B,ATG4A,TMEM179B,PDXP,SMC3,TNPO3,GEMIN4,MVP,NUP85,PABPC1,NSUN4,PPP6R1,PPA1,IFRD1,AGGF1,RBM42,FOXK1,GTPBP4,MAP7D1,MRPL16,ELK1,EIF4H,RDH11,MAGED2,KPNA1,ETS2,TYW5,WIPI2,RUFY3,PDLIM5,ACSF2,FAM72D,EXOC3,RHOG,C5orf30,VTI1A,STARD7,SLC35B2,LCLAT1,CPNE3,KIAA1147,AHCTF1,TBC1D14,GMEB1,NSFL1C,SEPT11,GPD1L,PDCL3,SNX8,ERMP1,EID1,IDH3A,NBPF11,POLR2D,HTATIP2,MEF2D,TMEM147,GSTCD,MAT2A,VPS26B,CORO1C,CAMKMT,PPP5C,PITRM1,TUBB,COMMD10,CCM2,HABP4,FLOT1,ABHD14B,ATG2B,ATP5F1B,NEXMIF,TUT4,PPP1R3B,GOLM1,HUWE1,ZNF260,NAA50,ANXA5,LTN1,KANSL2,UBE3B,NAP1L4,ST8SIA2,RPL22L1,MED22,SPTAN1,STAU1,DDX24,TCTEX1D2,TACC1,MRS2,LDHA,HEBP2,RAB3IP,PICALM,SH3BP5,PARG,ACOX1,FAM3C,PARP10,YWHAH,WDR45B,FAM129A,TRIM11,YTHDC2,RBM8A,SNX15,ENSA,SND1,RUFY1,TRIM65,PRNP,KRR1,RAB8A,NUP210,NOC2L,EIF5,TACC3,RYBP,PTPN18,MIOS,SNRPB,CDC6,ODC1,USP21,TRAM2,GRIPAP1,ARRDC1,DVL1,NUMB,CTU2,CENPF,LAMTOR3,CHCHD2,NCKAP1,RSAD1,TNS3,RINL,MBD2,KIF13B,XPA,AHCY,RBM3,GLE1,MRPL48,LRSAM1,NSDHL,AMD1,CAMSAP1,STYXL1,APPL1,BBS12,SDHB,PCM1,GALNT2,TMEM168,NLRC5,RUVBL2,BTBD10,MYO9A,CCNB2,ECPAS,USP7,GLT8D1,RPLP2,SUCLG1,TMX4,SLC2A1,ATP6V1B2,LYN,PCBP1,BCAP31,MRPL50,VAV1,PSMA6,BRPF3,TARDBP,BCAP29,PRPF19,PPIF,CLCN3,BIRC3,RAB7A,PPIE,CHMP2B,VDAC1,TMEM201,EIF3H,GLOD4,IDE,DHX16,CHMP4B,XRCC3,PARD3,NIFK,MTERF1,KLHL21,PDAP1,TMX3,CDCA8,ARF1,CDK11B,TUBGCP2,DNAJB9,HOMER1,POLR1B,RNF5,RHOA,ARHGEF12,DDX23,RAB18,TRIM26,PDCD6,NEK1,ATP6V1D,FAM110A,CTBS,BBX,IMPDH1,NR2F2,PGAM1,ARHGAP23,HIPK3,IFI16,TXN,PNISR,TMEM203,PRKCSH,UBE2I,PARK7,SLC25A37,GLMP,RAB4A,TRA2B,SUCLG2,TAF5L,CISD2,CDC5L,SGCE,NSUN2,CLNS1A,EIF3A,ZMYM3,MKNK1,WAS,KIF18B,TPP2,C1orf109,FAM72C,B4GALT2,RECQL,C9orf78,EWSR1,GADD45G,RRM1,DNAAF5,ACAP1,B4GALT1,CYCS,FAM136A,TMEM165,WDR48,SPAG5,NPLOC4,CNOT3,RTKN,TMEM250,CEP104,EXOSC7,KLHL5,LRRC8D,PIGG,OSTF1,FBXL7,MRPL40,TNRC18,SYTL3,APOL1,EIF5A,GCC2,COQ8A,RDH10,USF3,MFNG,RPS24,GORASP2,CAPZA2,ADRB2,MTR,CCT8,PFDN5,GOLGA2,MED15,APPL2,SAMD8,CDKN2A,NUDT3,NDC1,ATXN3,RAF1,CD320,CCNA2,MTMR4,BRI3,TAP2,TP53BP2,ILKAP,BRD4,LRRC8A,ELP4,ABHD11,PKMYT1,ASB13,SERP1,EIF3K,CHMP4A,CERS6,ATF6,XRCC4,NDUFS1,MECP2,SECISBP2,SPDL1,WWP2,JAKMIP1,SLC25A36,DNAJC8,ELP5,AXIN2,KAT2A,ANKRD37,TMEM126B,RABIF,ADSL,PACS1,KCNQ1,OTUD3,ARSK,MACF1,KLF6,COMMD4,KIF11,FADD,SH3GLB1,SMAP2,SELENOW,INF2,TMEM127,PPP1R11,DDX5,WDR62,TAF6,ESPL1,PURA,DEF6,IPO4,FAM83G,DDB1,PIGM,LYRM4,PTP4A3,UBE2Q1,MRPL19,PCYOX1L,CDC42,SYNM,GOT2,JAZF1,HADHB,SLC35C2,CARM1,SRPK2,WDR41,LARS,LRBA,RIOX2,TMEM216,SUMF2,OGFR,MPC1,RPL37,MAN2A2,EIF4ENIF1,NIP7,MIA2,ZNF268,VPS4A,ATP6V0E1,PPP1R2,PM20D2,XPNPEP3,RGS2,LYAR,EI24,FAM89B,GBA,SYVN1,EIF2A,DAPK3,ARHGAP15,MASTL,UAP1,FN3KRP,YWHAZ,CTSA,TMEM14A,TOB1,TCF12,PRKAB1,MDH2,ORC1,UBXN2A,IARS,CD3EAP,KIF14,EXOSC1,CS,CLTB,DNAL4,CHP1,UBQLN4,NXT1,PPP1R18,SMU1,ATXN1,GLO1,BICD2,OGDH,EDEM2,TOLLIP,MBD3,RPS9,PDHX,ALKBH6,DUS3L,SURF4,ARNTL,ANP32E,FKBP5,CCDC125,PDCD2L,ABCA1,GCLM,RAE1,DCTN2,CHIC2,PAWR,PIP4K2A,XPR1,FERMT3,KIF5B,KLHL20,SEC24C,RRBP1,DUS2,ARHGEF2,ANP32A,STAT3,MYO5A,AMPD2,TXNL1,COA3,DCAF6,FAM49B,ATP2C1,RFFL,COG1,PRMT2,TFEB,LEMD2,CTSL,UPF1,ELMO1,DTX4,ZMIZ1,HRAS,TERF1,CCDC93,TMED7,FGFR1OP,MAP3K7CL,PIGQ,AGPAT1,CNTROB,PPP1R16B,MIEN1,MIS12,CIPC,GSDMB,PDS5B,NUP153,SENP1,PGAP2,TMEM115,AATF,PLEKHF2,BRMS1,TRIM47,WDR11,AXIN1,SMG9,LONP2,NDUFV2,PHF23,CERK,ITGB5,LMNA,MCTS1,DDX56,EIF2S2,CARS2,RB1CC1,PRRC2A,PGS1,SRSF5,MPG,CYB5A,NCDN,PTAR1,CNOT6,NDE1,EGLN1,ZNF207,ANKRD27,ABCA3,SARNP,IVNS1ABP,RMI2,TMEM97,MON1B,NUF2,RXYLT1,NIT2,KTN1,APP,PRKD3,ATP2A2,GRSF1,DUT,ZCCHC2,ANAPC7,RNF19A,CLN6,GCC1,TMEM9,ATP6V1G1,ADCY7,ENPP4,RNPS1,CDCA2,FKBP3,DDX17,CHCHD3,PEX5,CDC16,HIPK2,NT5C3B,MBOAT1,TICAM1,PDXK,TMBIM4,ANXA6,UBE4A,ETS1,WRB,PLPP5,PNO1,CAPN2,ADD3,TPCN1,TMX1,HNRNPM,LYPLA2,MFSD12,LDHB,PPP3CA,JTB,MTMR12,PDE3B,CIP2A,KIF18A,CCDC6,WNT5B,MAPK6,C4orf46,SLC25A19,RGL1,PSAP,IGBP1,FAF1,SNAPIN,COX15,AGRN,THOC1,GNPDA1,PPP1R15B,CSNK2A1,BIRC2,GIT2,ATPAF1,ABL2,DLG5,XRCC2,ZFYVE27,MCMBP,CDC37,METTL1,EXOSC6,HARS,CYSTM1,ESYT1,ANLN,RAB5B,RHEB,DPYSL3,TBC1D17,CDCA4,TIMM13,TONSL,NAGLU,ACTB,C2CD5,TMUB1,ASAH1,DOCK11,CRLF3,LRRC14,NUS1,CMTR2,SLC27A4,MDFIC,CYTH1,NQO2,UTP15,EIF2AK1,EIF4G2,ZDHHC3,SPATA33,MOSPD3,CDC27,SNAP23,TBPL1,PRMT7,ATP5F1A,KCTD7,NDUFA5,CYLD,UGP2,DYNLL1,COPE,HCFC1R1,ZADH2,GGPS1,RPAIN,RAD23A,SEC11A,PDK2,ATP6V0B,ZBTB21,STRBP,TNFAIP8,DUS4L,MRPL34,PDCD2,RPL29,TIMP2,RPL35,BTG2,TUBGCP5,FRAT2,DNAJC9,MTMR6,NFATC2,USP36,MRPL2,ATP1A1,CLK3,PSMD3,NDUFA11,CEP55,ZNF436,DNAJC17,NCOA1,SLC25A39,ZNF146,SMAP1,GOLIM4,GNE,ARFIP2,CHAC2,BZW2,WRNIP1,SS18L1,CENPM,PTGES3,CAMK2G,MLEC,RHOT2,NEU1,GOLGA7,PGRMC1,GLG1,FAM126A,SPCS3,RPS6KC1,UBE2C,PPCS,NDUFB6,ZDHHC8,CCNB1,COMMD6,POLR3K,ABHD14A,RIC1,C14orf119,SNUPN,ASAP2,TFG,PLCL2,SPTSSA,SEH1L,ATG9A,ARHGAP45,DDX20,GALNT7,SLC17A5,AMDHD2,CCNF,FOXRED1,WDR4,DHTKD1,SARAF,TRAF5,HDAC2,HSPH1,MAPRE1,CHTF18,ADO,KIF23,SLC35B1,PMF1,NOTCH2,COPG2,JMY,NDUFAF6,FKBP1A,SLC31A1,SNX18,ATIC,CTPS1,SLC25A51,ATP6V0A2,RNF135,PIKFYVE,LPCAT1,EEF1D,TMED2,FTL,DDX28,SIGMAR1,PIP4K2C,PLEC,CYFIP2,KDM3A,FAS,EPRS,CSNK1G1,QARS,PPP3R1,TCOF1,NRBP1,CABLES1,DNMT3A,RWDD1,TRIP10,RPS6KA1,CAST,GPR89A,RAC1,OLA1,SNN,GNB2,FLAD1,APLP2,CDKN1B,TNPO2,TALDO1,GPX4,ATP13A1,MAPRE2,ERF,TAOK1,CUL3,SLBP,POLG2,PSMB9,DHX57,CENPU,SOCS7,HSPA4,JAK1,MRPL55,FAAP100,GOLGA8A,SEL1L,B4GALT3,PDCD11,CSNK1D,POLQ,OTUD5,ANKRD13D,PKP4,TWNK,BABAM1,CDCA3,SLC25A12,BLM,RPL17,CRAT,AHSA1,PRC1,UPF2,SLC38A10,COPS7B,CNOT6L,CNPY3,IFT46,UBE2M,STRIP1,DENND1B,DENND4C,WDR18,ILF3,RPL8,LRRC1,RHOT1,MARK2,ECH1,PRDX1,POLR2A,FBXO21,NUCB1,GNA12,PLD3,PFDN4,PRDX3,CCZ1B,STX18,TFDP1,NAXE,KHSRP,ASNA1,CPEB2,BYSL,VPS29,S100PBP,DDX52,MIB2,ADA2,IER2,NF1,ALKBH5,MOGS,UBE2Z,MAPK14,BECN1,RNF103,BCAT2,CYREN,IMPAD1,PHTF1,SRI,KHDC4,KIF22,NFU1,OGG1,TRIM14,COPS8,TRIM8,RRM2,SOX4,ABHD5,PAF1,CXXC4,SPATA2,ATXN2L,PQBP1,IARS2,GALNT10,ROCK1,STARD3NL,CEP170B,RPS15,PIGN,AGTRAP,CDIP1,CIB1,XPO7,SRRT,APOPT1,CAPZA1,KIFAP3,BCL2,GLTP,N4BP2,VOPP1,ISG15,CAND1,GNAS,TSC1,RBM25,CDCA5,RBBP4,NANP,NIPSNAP2,HNRNPDL,WASF2,MMACHC,TOMM20,FAM92A,IFI27L1,MPHOSPH8,GNPNAT1,CHD1,MIEF1,BABAM2,CCDC50,AKAP8,PARL,RPN2,CHTOP,F2R,ABI1,TMEM14C,SCYL3,HTRA2,RLIM,MOSPD1,FAM172A,ZNF500,PSMB7,NLN,WIPF1,BOLA1,ERBIN,NDUFB1,PEF1,EIF3G,BTBD1,TAB2,TULP3,CHCHD1,WDR59,CANT1,SCARB1,GAS2,USP11,SMURF1,PPP2R2D,CDS2,MAGEH1,MRPL42,EYA1,CDK2AP2,MRPS26,LETMD1,HDDC2,RGS1,MAN1A1,FBXO5,GART,PELO,TANK,BRD7,MRPL11,SAMD4B,ZDHHC18,POLR3GL,WDR81,MEN1,MFN2,COX8A,SRSF3,ATP6V1C1,IDH3B,TSC2,LACTB2,RBM4,CMTM6,RPL23A,CDKN2C,USF1,NAPG,DNAAF2,AP1M1,MECR,UPRT,CRY2,ECD,MOB1A,RNF26,LRRC59,RHBDD2,MGAT5,ANKRD9,MRPL57,BAK1,RHOBTB3,NUTF2,COA7,GINS4,ARF4,KRIT1,BOLA3,AHNAK,RAD18,PDRG1,RNASEL,CHPF2,OAZ1,SMNDC1,PDCD4,NXT2,HIVEP3,CLSPN,RHOC,DHX9,PSMD9,HAUS2,COPB2,CD59,TFAP4,RNFT1,RIMS3,EFTUD2,FBXO7,MYDGF,MRPL21,PHKG2,EIF3L,MAPKAPK3,ERO1A,MTFR2,SSR2,USP10,ITM2A,BCLAF1,MTX1,SFXN5,FNTA,PDLIM1,TXNDC16,CFAP20,MRPL3,ALS2,FAM72A,KARS,TRIM41,GGNBP2,NQO1,POC1A,ANK3,PTTG1,TPX2,TBC1D13,DAZAP2,STMN1,GLRX3,REPS1,SH3BP1,MTA1,UBA5,CLCN6,NABP1,MICU2,RPRD1B,CPNE1,ULK3,SEC61B,POLR2L,KAT7,GOPC,CIRBP,RPL38,PFKFB3,GORAB,RAB1A,KIF2A,PPP2CA,ALDH3B1,LSM6,CCDC14,SNRPG,USP13,MZT1,TRMT6,SLC25A43,IFT27,PMVK,NEIL2,SAPCD2,SRXN1,PSMD2,CLIC4,PDCD10,COQ4,ARF5,ARHGEF1,FBXL19,UTP20,MAGT1,GPS2,DBI,SSNA1,AAMDC,FANCI,CREM,PAPOLA,FANCL,TET3,GLIS2,TIMM23,POP7,SLC44A1,ASB6,MTPN,PLK1,SEPT9,CELSR2,APH1A,RBX1,ZBED5,CKAP2L,PSMG1,UBE2V1,KRTCAP2,LSG1,NECAP2,TRIM4,ALG3,AGPAT2,CHD3,KPNA2,CLN3,DNAJC30,NGLY1,MYL12B,RMND5A,HJURP,PHB2,DNAJB2,SDC2,NKD2,KLC1,CDK13,COX4I1,DNAJB1,RAB6A,CNOT11,ARID1B,C1GALT1,UBE2Q2,MLX,CCP110,ZNF746,ARL6IP1,ICE2,NIPSNAP1,ABHD2,DCAF8,ACSL3,MAP4K3,ARMC8,RMC1,IRF5,NMT2,RBM38,RPL36,HAUS8,MBIP,ORMDL2,LAMTOR4,COX7A2L,SIL1,ZDHHC7,DTD1,UNC13C,BCCIP,SART1,TRAF7,NDUFAF2,LAGE3,RRAGC,ZFYVE21,OIP5,NRF1,ABRAXAS2,WDR44,PIN1,AHCYL1,TOP1MT,LMAN1,STRAP,SPSB3,SNX25,ARHGAP17,POLR2G,PPT1,DCLRE1C,MRPS14,RHBDF2,AFDN,STK38,FASTK,UBXN2B,AP1S1,SMAD4,CHID1,RAD51D,SLC30A9,UNK,NADSYN1,AGO2,HMGN3,NCAPG,SCYL2,FZD6,GTPBP3,HERC3,CTSS,ACP2,PRKDC,ABCF2,TUFM,RANGAP1,PNPLA8,API5,HAGH,ZFR,SEC23IP,E2F1,USP20,RBPJ,PDCD6IP,MAX,ADAM10,CXXC1,TSC22D3,AP3M2,CUL1,GYG1,NANS,OAT,MYEF2,MTFR1L,PA2G4,FIZ1,AP2B1,FBXW2,MARCH2,SRSF10,SRP72,LACTB,RAB2B,MAP3K4,HHEX,BRD2,RPS14,MRPL27,MAP4,PTPDC1,BTF3,SLF1,NMD3,PTOV1,COX5B,DNAJC5,SCOC,POLR2K,DHPS,VAV2,PRKAA1,GSPT2,PXMP2,PSEN1,VPS25,PDXDC1,YY1AP1,NDUFS7,C12orf10,RPN1,ZNRF2,ARPC5,TPST1,DAPK1,CYC1,MRM3,SOCS5,FDFT1,PIGT,CPQ,WDR1,C1orf35,EXOSC9,FXR1,PTTG1IP,GOSR1,MAP2K2,XRCC5,PI4K2A,HMGN2,AKAP1,CAT,SEC31A,DERL1,MTHFD2,HSPBP1,ARAP1,USP32,FAM83D,CABIN1,GPI,SMPD4,CYTIP,TP53RK,REPS2,RAB11B,UROD,SLC39A13,BCL2L1,POMP,NUDT19,DECR1,RALB,SIAH1,LPIN2,ADCY9,MRPS27,SOCS6,TTC3,RNASEH2A,CFL1,ANKLE2,CDC123,VDAC2,EDF1,EML4,ERC1,ANKZF1,RAD51C,DDOST,HINT1,DSN1,DGCR8,RAB24,FTSJ1,NCLN,EYA2,DYNC1LI2,MANBA,B4GALT5,TKT,CBLL1,ARGLU1,LANCL1,POFUT1,HLA-A,HEATR5B,EBP,RFWD3,NDUFA2,FUT8,PTPN11,FEM1B,MRPL54,RPL19,CNN2,NDUFA3,MTX2,MSH6,PDLIM2,RFXANK,FBXO9,GUF1,SPPL2B,RPL32,OAZ2,NDUFS5,WDR91,HIGD2A,GPR89B,POLA2,ZBED3,COPA,MTX3,KMT2E,UQCR10,ABCB10,COMMD5,ATP5PF,MAP1LC3B,DST,SIVA1,RAB35,CARMIL1,DRAM2,DEAF1,TRAPPC13,LAP3,NCK1,VHL,ARHGDIB,PITPNB,BRWD1,PPM1G,SH3GLB2,CAB39,CRCP,STK11,CLU,CHEK2,MRPL13,CHPT1,CAPN1,UBE2D3,PPP1R12A,GORASP1,UBXN1,NACA,RPL15,EPN1,PCSK7,TTF1,QSOX2,CHKA,DTL,PYURF,ZRANB1,MCPH1,ATP6V0D1,CSNK1G3,ATP5IF1,CREG1,NUDT4,ERLIN1,RPL6,VKORC1,EVC2,SIAH2,DNPH1,SNRNP70,EHD4,APOL2,CHMP2A,SNX27,FEZ2,CORO7,UCK2,PMS2,UCK1,CLCC1,EXT2,MXD1,USP5,HNRNPA2B1,PPP6C,CYB5R1,EBAG9,RNF25,FAM72B,PON2,VPS26C,HNRNPR,STAT6,HPS5,MAPK1,PDF,TMEM33,DNAJC2,TRIP12,SCYL1,VPS45,MYO9B,GFM2,SPPL2A,FASTKD3,FGFR3,MZT2A,GRK2,PPIG,KMT5A,NABP2,ZDHHC13,NDUFS8,ATG13,SLC35A1,MICAL3,TGFB1,B3GALT6,PPP1R9B,ELOVL5,HEMK1,TIMMDC1,PSPC1,HELB,MIER1,NADK2,NDRG3,CDK11A,MTMR3,ACAT1,CENPT,PLOD3,RAB3IL1,RAB14,ADD1,MRPS15,KDM4A,XIAP,DHX8,GLUD1,ANKRD23,PABPC4,CDK5,CALM2,PSMD1,NEK6,RABGAP1L,FNIP2,PCBP2,KCNAB2,MLST8,PLK3,HSDL1,MRPL43,TOPORS,MCL1,SMC2,PPFIA3,ICMT,SLC50A1,STOML2,LIMK1,PRDX5,MLYCD,VIPAS39,ATE1,ATP6V0C,ST3GAL2,TFDP2,FBXL3,PFKP,AAAS,DDX42,MRPL9,MRPS2,STRN4,TOP2B,TMED3,DDRGK1,RAVER2,GNS,INTS7,MCM5,RTCB,NAGPA,TIMM8B,CYFIP1,DHX29,TEX10,MAN1B1,RPS10,ABCF1,RHOB,SCARB2,OSBPL11,CSK,DUSP3,SLAIN1,MDH1,HEXA,RNF139,SNX14,FAM208B,TRERF1,UBR2,ACTR3,CHD1L,WDTC1,MYH9,NIPA2,PRKACA,SAFB2,ANKIB1,STAM,RAB21,SP100,NUP107,ANKRD13C,MAVS,CEP63,ATF2,DCTN1,SHOC2,PSRC1,MAP4K4,INTS13,WBP2,ATP6V0A1,NUSAP1,DNAJA1,NDUFA7,TAZ,SEC61A1,RPLP1,WDR7,RBMS1,FUS,LRCH1,GALK1,RPS2,TRAK1,SIKE1,JMJD6,AKT1S1,FBXO3,ERH,GATC,NDUFB4,PPP1R8,PRDM4,GEMIN6,GTSE1,DCP1A,SGCB,IMPA2,S100A6,NUDC,MOB4,PDPK1,TK1,TNFAIP3,GUK1,GALC,MRPS10,DDX39A,KEAP1,TATDN2,CAPN7,PITX1,PML,LRPPRC,HMGB2,USF2,ANAPC4,SRM,DDX47,MCCC1,CDC42SE2,CDIPT,SEC16A,KCMF1,SSR1,PIK3R2,TRMU,ETV6,TXLNA,PPCDC,CCAR1,MRPL32,BAZ2A,PBXIP1,MRPL12,EZR,LRP5,BRCA1,PRKRA,STX16,EPB41,OPTN,SEPT1,SOCS4,QRSL1,DHFR2,PIEZO1,OSGEPL1,GLCCI1,NUDT11,NAA60,GEMIN7,SEPHS2,LZTR1,RACGAP1,PPP3CB,B4GALT4,RAPGEF6,SNRNP25,VASP,TIGAR,VMP1,PPIL2,MEA1,TMEM8A,ALDH18A1,ABCC1,PREB,TRAPPC9,AACS,MEMO1,KRAS,NFATC2IP,UBE4B,ARPC1A,ZNF174,PSMC4,GOLGA4,SYNCRIP,NIPA1,RNF114,MRPL39,DUSP22,COMMD8,RPL11,CSDE1,MDM2,CORO1A,MINPP1,DVL2,POC5,GM2A,PSMA8,COQ10B,CPOX,SLC26A6,PRPF3,TXNL4A,RPSA,SRSF1,DNAJC10,SCAP,TIMM17A,TOMM6,LTA4H,AP2S1,INTS2,CTDP1,MIF4GD,CDT1,SUMF1,GGA2,AP3S1,CSNK1A1,TFRC,PTPN2,GSTK1,STARD9,IRF4,NDUFV1,SLC1A4,SLC35B4,DDX31,ABCD1,RPAP3,CNTN5,SNX2,ZMYM5,BORA,CHCHD6,FBXO41,KPNA4,BIRC5,SNAP29,TFE3,CDCA7L,PKD2,ACADM,CHMP7,SAT2,GCSH,TAP1,TMEM109,YTHDF3,NHLRC3,IKBIP,KIFC1,CYB5RL,DBNDD1,PARPBP,MAST2,CDC25B,USO1,AKT2,AURKB,MCFD2,ZFAND5,SLC25A5,TMED10,STT3A,PSMD8,EIF2D,ITGB1,PTPN7,UQCRH,RRS1,ARRB2,RTN3,SVIP,WSB2,DDX58,PPIB,GMFG,MUT,HLA-E,NDUFA4,MAN2B1,METTL3,NDUFS4,CFLAR,RNF121,MEX3C,DAD1,HDAC7,BDH1,PCYT2,GNAI2,ANKHD1,NOA1,KCTD20,SEPT8,DCTD,TOMM40,PKM,PATL1,PSMB3,ADSS,SERTAD2,SERF2,NSF,DCK,ERGIC3,LPCAT4,ACLY,VCPIP1,PPP6R3,MAP3K5,PPP6R2,YY1,CDK2,RNF14,ZC3HAV1,SYS1,MAGED1,EIF3D,ADPGK,AP1B1,SLC25A44,SDHA,PAIP2,CRKL,TERF2IP,MOAP1,CYHR1,SHC1,UCHL5,NAA35,TMBIM1,MRM2,CCT2,MKLN1,LYRM1,GALK2,CDC23,SHCBP1,AP4E1,PRDM11,PPP2R5A,GUCY1B1,PPA2,STAT1,TRIM32,RHEBL1,TCF3,MRI1,BRAP,AGPAT3,SDF2L1,SPR,RAB11A,FOXO3,REEP5,MAD2L2,PIP5K1C,MAT2B,PTEN,CENPJ,TAGLN2,MAP3K14,CREB1,OSTC,NCOA2,PACS2,SMC4,NET1,NEK7,PARP4,TBRG4,ANAPC2,RPL27A,YIF1A,SGSH,HGS,TTLL4,ATP5MC3,CCDC69,ESYT2,SKA3,NPHP4,HNRNPAB,ST13,DNAJC24,AGFG1,SIRT2,KIF2C,SNRPD3,UBQLN2,FKBP2,USP48,CUTC,EDC3,ZNF804A,RAP1A,EIF4A3,THADA,AP3S2,DPYSL2,ATG3,PPP1R12C,AKR1B1,JOSD1,NDUFB9,RP2,TTC4,TECR,ARID4A,FGFR1OP2,TIMM50,TDP1,DPM1,FOPNL,SLC25A22,STK17B,DHX15,GEMIN5,TIMM29,COPS6,SASS6,RPS26,PSMC1,TBC1D12,TM9SF4,UFC1,TIA1,MEF2A,EPHX2,RHBDD1,NFATC3,BANF1,YBX1,KNTC1,UBE3C,ACAD8,ALDH9A1,KDELR1,TSTA3,OXR1,PSMA1,SEPT7,NAP1L1,NSMF,ODF2,EXOC4,NUP62,TRMT10B,PITPNA,NAA20,MZT2B,PDSS2,PTDSS1,TMEM106C,IMMT,ASH1L,CHERP,WDYHV1,IRF3,CHKB,TWF2,PAIP1,ANKRD28,FARSA,ANKLE1,SAR1A,APOOL,PDIA6,ACSL5,CGAS,DMAC2,TOR1AIP2,AZI2,GFER,DAP3,GADD45B,AKNA,REEP4,MIF,KIF3B,GOLPH3L,CASP6,TOR3A,SRGN,TIMM21,MFSD10,SAC3D1,CTNNBL1,YIF1B,TTC17,SLC25A1,GINS1,TELO2,CSNK1G2,HMGN1,ADAM17,NASP,ASPM,PRKAR1B,ATP5MF,SYMPK,TARS,HSPA1B,MAPK3,CNOT9,HLA-B,PLAA,OSBPL8,KBTBD7,PREPL |
| 1.425e-65 | -149.31 | cytosol | cellular component | GO:0005829 | 5011 | 1121 | 18223 | 2701 |
TSC2,TGOLN2,RBM4,FBXO22,EEF2K,RPL23A,CDKN2C,DNAAF2,RAD23B,AP1M1,DNM2,UPRT,CRY2,ECD,MOB1A,ANKRD9,USP34,BAK1,ERCC1,RHOBTB3,KIF15,HNRNPF,NUTF2,ARF4,AHNAK,MID1IP1,SMAD2,RPS27A,OGT,RNASEL,KLHL42,SMAD1,OAZ1,ANXA11,PDCD4,NXT2,SEC61G,CCZ1,RHOC,MUM1,TRIO,DHX9,RAB23,HAUS4,EIF2AK4,PSMD9,PARN,HAUS2,CDC73,MYL6B,COPB2,ATG4A,PDXP,SMC3,FBXO7,EFTUD2,GEMIN4,MVP,PABPC1,NUP85,PHKG2,PPP6R1,PPA1,EIF3L,MAPKAPK3,GTPBP4,USP10,MAP7D1,EIF4H,MAGED2,FNTA,KPNA1,ETS2,WIPI2,RUFY3,PDLIM5,ALS2,FAM72A,FAM72D,RHOG,EXOC3,KARS,NQO1,PTTG1,ANK3,VTI1A,TPX2,TBC1D13,STMN1,GLRX3,LCLAT1,CPNE3,REPS1,AHCTF1,SH3BP1,MTA1,TBC1D14,UBA5,NABP1,NSFL1C,GPD1L,RPRD1B,PDCL3,SNX8,CPNE1,ULK3,SEC61B,POLR2L,KAT7,RPL38,POLR2D,HTATIP2,PFKFB3,GORAB,RAB1A,MAT2A,PPP2CA,KIF2A,ALDH3B1,VPS26B,LSM6,CAMKMT,SNRPG,PPP5C,USP13,MZT1,HABP4,ABHD14B,PMVK,SAPCD2,TUT4,SRXN1,PSMD2,PDCD10,CLIC4,HUWE1,ARHGEF1,ZNF260,NAA50,ANXA5,LTN1,KANSL2,FBXL19,RPL22L1,SPTAN1,STAU1,LDHA,RAB3IP,PICALM,GPS2,PARG,SSNA1,PARP10,WDR45B,YWHAH,FAM129A,TRIM11,RBM8A,SNX15,SND1,RUFY1,TRIM65,FANCI,PRNP,RAB8A,NOC2L,EIF5,MTPN,ASB6,TACC3,PLK1,PTPN18,MIOS,RBX1,SNRPB,PSMG1,CKAP2L,CDC6,UBE2V1,ODC1,USP21,LSG1,TRIM4,GRIPAP1,KPNA2,DVL1,DNAJC30,NGLY1,MYL12B,CTU2,HJURP,DNAJB2,CENPF,KLC1,CDK13,RAB6A,NCKAP1,DNAJB1,CNOT11,ARID1B,TNS3,MLX,UBE2Q2,CCP110,MBD2,KIF13B,AHCY,ICE2,GLE1,LRSAM1,DCAF8,AMD1,APPL1,RBM38,NMT2,IRF5,BBS12,HAUS8,RPL36,MBIP,PCM1,NLRC5,DTD1,RUVBL2,MYO9A,CCNB2,BCCIP,USP7,SART1,RPLP2,SUCLG1,SLC2A1,ZFYVE21,RRAGC,ATP6V1B2,LYN,PCBP1,BCAP31,OIP5,VAV1,NRF1,PSMA6,BRPF3,WDR44,ABRAXAS2,PIN1,AHCYL1,STRAP,SPSB3,ARHGAP17,BIRC3,PPT1,RAB7A,PPIE,CHMP2B,EIF3H,AFDN,IDE,UBXN2B,STK38,AP1S1,CHMP4B,XRCC3,SMAD4,PARD3,NADSYN1,MTERF1,KLHL21,PDAP1,AGO2,CDCA8,HMGN3,ARF1,NCAPG,TUBGCP2,HERC3,HOMER1,POLR1B,RHOA,PRKDC,RANGAP1,ARHGEF12,HAGH,RAB18,SEC23IP,TRIM26,ATP6V1D,BBX,IMPDH1,USP20,NR2F2,PGAM1,ARHGAP23,HIPK3,IFI16,TXN,PNISR,PDCD6IP,TSC22D3,CXXC1,CUL1,NANS,GYG1,UBE2I,PARK7,GLMP,RAB4A,AP2B1,FBXW2,SRSF10,SRP72,LACTB,CLNS1A,EIF3A,MKNK1,WAS,KIF18B,RPS14,TPP2,MAP4,BTF3,FAM72C,C9orf78,SCOC,DHPS,POLR2K,VAV2,PRKAA1,GSPT2,RRM1,ACAP1,CYCS,VPS25,CNOT3,NPLOC4,RTKN,RPN1,EXOSC7,KLHL5,ARPC5,ZNRF2,FBXL7,TNRC18,SOCS5,EIF5A,GCC2,WDR1,RPS24,EXOSC9,CAPZA2,FXR1,GOSR1,MTR,MAP2K2,CCT8,AKAP1,XRCC5,PI4K2A,CAT,SEC31A,MTHFD2,ARAP1,APPL2,USP32,SAMD8,CABIN1,GPI,NUDT3,CDKN2A,CYTIP,ATXN3,TP53RK,REPS2,RAB11B,RAF1,UROD,POMP,BCL2L1,DECR1,CCNA2,SIAH1,MTMR4,LPIN2,ADCY9,SOCS6,TTC3,RNASEH2A,TP53BP2,ILKAP,CFL1,BRD4,EDF1,PKMYT1,ASB13,ERC1,SERP1,EIF3K,RAD51C,CHMP4A,DSN1,HINT1,RAB24,FTSJ1,ATF6,XRCC4,EYA2,DYNC1LI2,MECP2,TKT,CBLL1,SPDL1,WWP2,DNAJC8,ELP5,FUT8,PTPN11,AXIN2,FEM1B,RPL19,MSH6,ANKRD37,RFXANK,RABIF,ADSL,FBXO9,PACS1,OTUD3,KIF11,KLF6,FADD,SMAP2,SH3GLB1,RPL32,OAZ2,WDR62,WDR91,TAF6,ESPL1,DEF6,FAM83G,ZBED3,POLA2,COPA,UBE2Q1,COMMD5,MAP1LC3B,DST,CDC42,RAB35,JAZF1,CARMIL1,CARM1,SRPK2,TRAPPC13,LARS,NCK1,LAP3,VHL,RIOX2,TMEM216,ARHGDIB,RPL37,EIF4ENIF1,BRWD1,NIP7,SH3GLB2,CRCP,CAB39,ZNF268,STK11,CLU,VPS4A,CAPN1,UBE2D3,PPP1R12A,UBXN1,EPN1,RPL15,RGS2,TTF1,CHKA,DTL,EI24,ZRANB1,NUDT4,RPL6,EIF2A,ARHGAP15,UAP1,SIAH2,FN3KRP,YWHAZ,DNPH1,SNX27,CHMP2A,PRKAB1,CORO7,PMS2,UCK2,UCK1,ORC1,MXD1,USP5,UBXN2A,IARS,CD3EAP,KIF14,EXOSC1,PPP6C,CLTB,CHP1,UBQLN4,NXT1,RNF25,ATXN1,GLO1,BICD2,OGDH,FAM72B,TOLLIP,RPS9,DUS3L,HPS5,STAT6,FKBP5,MAPK1,DNAJC2,GCLM,TRIP12,SCYL1,DCTN2,MYO9B,PIP4K2A,KIF5B,MZT2A,GRK2,KLHL20,KMT5A,SEC24C,PPIG,DUS2,NABP2,ARHGEF2,ATG13,STAT3,MICAL3,MYO5A,AMPD2,TXNL1,DCAF6,RFFL,PRMT2,MTMR3,UPF1,ELMO1,DTX4,ACAT1,CENPT,HRAS,RAB3IL1,FGFR1OP,RAB14,ADD1,MAP3K7CL,KDM4A,XIAP,CNTROB,MIEN1,ANKRD23,MIS12,PABPC4,CDK5,CIPC,PSMD1,GSDMB,NEK6,PDS5B,NUP153,PCBP2,KCNAB2,MLST8,MCL1,PPFIA3,SMC2,TRIM47,WDR11,AXIN1,LIMK1,PRDX5,SMG9,FBXL3,AAAS,PFKP,DDX42,TOP2B,LMNA,MCTS1,EIF2S2,MCM5,RTCB,CYFIP1,RB1CC1,PRRC2A,RPS10,SRSF5,ABCF1,RHOB,CYB5A,NCDN,CSK,DUSP3,MDH1,CNOT6,NDE1,EGLN1,ANKRD27,FAM208B,TRERF1,IVNS1ABP,UBR2,ACTR3,CHD1L,TMEM97,RMI2,WDTC1,MYH9,NIT2,NUF2,PRKACA,STAM,APP,PRKD3,RAB21,NUP107,ANAPC7,CEP63,RNF19A,GCC1,DCTN1,ADCY7,ATP6V1G1,SHOC2,PSRC1,RNPS1,ATP6V0A1,CDCA2,DNAJA1,TAZ,DDX17,CDC16,PEX5,SEC61A1,NT5C3B,RPLP1,RBMS1,TICAM1,PDXK,GALK1,RPS2,JMJD6,SIKE1,AKT1S1,PNO1,FBXO3,CAPN2,ADD3,DCP1A,GEMIN6,GTSE1,S100A6,LYPLA2,IMPA2,LDHB,NUDC,PDPK1,PPP3CA,TK1,GUK1,TNFAIP3,MTMR12,PDE3B,CIP2A,KEAP1,KIF18A,CCDC6,TATDN2,MAPK6,PML,RGL1,IGBP1,ANAPC4,FAF1,SNAPIN,SRM,THOC1,AGRN,GNPDA1,MCCC1,CSNK2A1,SEC16A,KCMF1,GIT2,BIRC2,ABL2,ETV6,PIK3R2,PPCDC,TXLNA,ZFYVE27,MCMBP,CDC37,METTL1,EXOSC6,BAZ2A,HARS,PBXIP1,EZR,PRKRA,STX16,RHEB,OPTN,DPYSL3,EPB41,CDCA4,TBC1D17,ACTB,NUDT11,C2CD5,GEMIN7,SEPHS2,TMUB1,RACGAP1,PPP3CB,DOCK11,CRLF3,RAPGEF6,SNRNP25,VASP,TIGAR,ALDH18A1,CYTH1,TRAPPC9,AACS,NQO2,MEMO1,KRAS,ARPC1A,EIF4G2,ZNF174,PSMC4,SPATA33,GOLGA4,CDC27,PRMT7,RNF114,KCTD7,CYLD,UGP2,DYNLL1,COPE,GGPS1,DUSP22,COMMD8,RPL11,RAD23A,CSDE1,PDK2,ZBTB21,MDM2,DUS4L,CORO1A,DVL2,POC5,RPL29,RPL35,PSMA8,BTG2,CPOX,TUBGCP5,MTMR6,DNAJC9,FRAT2,NFATC2,PRPF3,TXNL4A,RPSA,PSMD3,ZNF436,NCOA1,LTA4H,AP2S1,ZNF146,MIF4GD,SMAP1,CDT1,GNE,ARFIP2,CHAC2,CSNK1A1,PTPN2,IRF4,NDUFV1,ABCD1,SS18L1,PTGES3,CENPM,CAMK2G,RPAP3,CNTN5,SNX2,BORA,RHOT2,CHCHD6,FBXO41,KPNA4,BIRC5,TFE3,SNAP29,CDCA7L,FAM126A,UBE2C,CHMP7,PPCS,ZDHHC8,YTHDF3,CCNB1,RIC1,POLR3K,C14orf119,ASAP2,SNUPN,CDC25B,TFG,SEH1L,USO1,AKT2,ARHGAP45,DDX20,AMDHD2,SLC17A5,AURKB,CCNF,PSMD8,EIF2D,WDR4,PTPN7,DHTKD1,TRAF5,ARRB2,DDX58,WSB2,HSPH1,MAPRE1,CHTF18,ADO,KIF23,PMF1,COPG2,CFLAR,FKBP1A,MEX3C,ATIC,HDAC7,CTPS1,PIKFYVE,RNF135,GNAI2,EEF1D,DDX28,FTL,PIP4K2C,DCTD,PLEC,CYFIP2,TOMM40,PKM,PATL1,PSMB3,FAS,ADSS,EPRS,SERTAD2,SERF2,NSF,QARS,DCK,CSNK1G1,ACLY,PPP3R1,TCOF1,PPP6R3,PPP6R2,MAP3K5,CDK2,RNF14,CABLES1,NRBP1,ZC3HAV1,SYS1,TRIP10,CAST,RPS6KA1,EIF3D,RAC1,OLA1,AP1B1,GNB2,TERF2IP,MOAP1,FLAD1,CRKL,SHC1,UCHL5,CDKN1B,TALDO1,GPX4,CCT2,MKLN1,ERF,TAOK1,CUL3,SLBP,CDC23,PSMB9,CENPU,SOCS7,HSPA4,PPP2R5A,JAK1,GUCY1B1,FAAP100,GOLGA8A,STAT1,TRIM32,B4GALT3,PDCD11,CSNK1D,OTUD5,MRI1,BABAM1,CDCA3,BRAP,BLM,SPR,RAB11A,FOXO3,MAD2L2,PIP5K1C,MAT2B,PTEN,RPL17,CENPJ,AHSA1,PRC1,COPS7B,UPF2,TAGLN2,MAP3K14,CNOT6L,UBE2M,SMC4,STRIP1,DENND4C,NET1,DENND1B,RPL8,PARP4,ANAPC2,LRRC1,RHOT1,RPL27A,PRDX1,FBXO21,HGS,TTLL4,PRDX3,PFDN4,CCZ1B,TFDP1,KHSRP,NAXE,BYSL,VPS29,S100PBP,ADA2,MIB2,NPHP4,ST13,NF1,ALKBH5,UBE2Z,SIRT2,AGFG1,KIF2C,SNRPD3,UBQLN2,USP48,MAPK14,BECN1,CUTC,EDC3,RAP1A,EIF4A3,THADA,IMPAD1,ATG3,DPYSL2,SRI,AKR1B1,JOSD1,KIF22,NFU1,ARID4A,FGFR1OP2,COPS8,TRIM8,RRM2,ABHD5,GEMIN5,IARS2,PQBP1,ATXN2L,ROCK1,COPS6,SASS6,RPS26,PSMC1,STARD3NL,RPS15,PIGN,AGTRAP,TIA1,MEF2A,EPHX2,NFATC3,BANF1,CAPZA1,GLTP,YBX1,KIFAP3,BCL2,KNTC1,N4BP2,ALDH9A1,TSTA3,PSMA1,SEPT7,ISG15,CAND1,GNAS,TSC1,CDCA5,ODF2,EXOC4,TRMT10B,PITPNA,NAA20,NANP,RBBP4,HNRNPDL,MZT2B,PDSS2,WASF2,MMACHC,GNPNAT1,MPHOSPH8,WDYHV1,IRF3,CHKB,PAIP1,ANKRD28,FARSA,BABAM2,CCDC50,PDIA6,ABI1,HTRA2,RLIM,CGAS,ZNF500,PSMB7,WIPF1,GFER,EIF3G,BTBD1,TAB2,CHCHD1,GAS2,USP11,AKNA,SMURF1,PPP2R2D,MIF,KIF3B,GOLPH3L,CASP6,RGS1,FBXO5,MAN1A1,GART,TANK,BRD7,TTC17,SAMD4B,TELO2,CSNK1G2,ADAM17,PRKAR1B,POLR3GL,WDR81,MEN1,SYMPK,TARS,HSPA1B,MFN2,MAPK3,CNOT9,OSBPL8,KBTBD7,PREPL,ATP6V1C1 |
| 4.486e-65 | -148.17 | protein-containing complex | cellular component | GO:0032991 | 5122 | 1138 | 18223 | 2701 |
TSC2,CCNL2,SYNRG,RBM4,RPL23A,NAPG,USF1,RAD23B,AP1M1,DNM2,ECD,ZNRD1,FTSJ3,MRPL57,BAK1,ERCC1,KIF15,HNRNPF,WDHD1,MIER2,NUTF2,MCM2,GINS4,KRIT1,SMAD2,RAD18,RPS27A,PDRG1,MYO18A,OGT,COX5A,KLHL42,SMAD1,SMNDC1,NXT2,GGA1,CCZ1,DHX9,KCTD17,HAUS4,EIF2AK4,PDCD7,PSMD9,APH1B,HAUS2,CDC73,MYL6B,COPB2,TFAP4,SMC3,FBXO7,EFTUD2,GEMIN4,MRPL21,CPSF4,MVP,NUP85,PABPC1,PHKG2,NSUN4,LUC7L2,EIF3L,MTA2,SF3B6,USP10,MRPL16,EIF4H,FNTA,KPNA1,PDLIM1,WIPI2,ZNF830,MRPL3,NUP58,ALS2,EXOC3,KARS,VTI1A,INO80E,DAZAP2,RCOR3,AHCTF1,SH3BP1,NABP1,NSFL1C,SEPT11,MICU2,INTS12,GPD1L,ZC3H3,RPRD1B,SNX8,SEC61B,POLR2L,EID1,GOPC,KAT7,CRNKL1,RPL38,CIRBP,E2F3,POLR2D,TMEM147,MAT2A,GIGYF1,PPP2CA,KIF2A,VPS26B,LSM6,CORO1C,NSMCE2,CAMKMT,SNRPG,PPP5C,TUBB,MZT1,TRMT6,CCM2,HABP4,FLOT1,ATP5F1B,WDR5,IFT27,NEXMIF,RRP36,PPP1R3B,RPA2,PSMD2,CLIC4,ITGB8,COQ4,NAA50,LTN1,KANSL2,FBXL19,GTF2H2,RPL22L1,MED22,STAU1,TCTEX1D2,PICALM,UTP20,MAGT1,GPS2,RBM8A,SND1,ZER1,KRR1,PRNP,CREM,FANCL,NUP210,TIMM23,IL6ST,INTS1,POP7,NOC2L,MTPN,RYBP,PLK1,RPP25,SEPT9,MIOS,RBX1,APH1A,RAD51AP1,SNRPB,UBE2V1,IL12RB1,PBRM1,EAF2,UTP3,KRTCAP2,LUC7L,NECAP2,FBXO28,CHD3,E2F4,PRPF4,KPNA2,DVL1,POT1,MYL12B,RMND5A,CTU2,HJURP,PHB2,CENPF,LAMTOR3,KLC1,COX4I1,CDK13,NCKAP1,CNOT11,ARID1B,SUB1,CCP110,MBD2,SSBP3,KIF13B,XPA,ARL6IP1,CTR9,RBM3,ICE2,GLE1,MRPL48,LRSAM1,DCAF8,LDB1,METTL22,ARMC8,APPL1,NPIPA1,BBS12,RMC1,HAUS8,RPL36,SDHB,PAXX,MBIP,PCM1,ORMDL2,LAMTOR4,RUVBL2,MYO9A,ECPAS,BCCIP,USP7,SART1,TRAF7,RPLP2,LAGE3,RRAGC,ATP6V1B2,LYN,PCBP1,BCAP31,MRPL50,PSMA6,BRPF3,ABRAXAS2,TOP1MT,STRAP,SPSB3,PRPF19,PPIF,BIRC3,POLR2G,RAB7A,PPIE,NUP155,DCLRE1C,CHMP2B,VDAC1,MRPS14,EIF3H,SUGP1,IDE,DHX16,RBL1,AP1S1,CHMP4B,XRCC3,H3F3A,SMAD4,RAD51D,PARD3,UNK,MCM10,KLHL21,AGO2,CDCA8,ARF1,PAGR1,NCAPG,TUBGCP2,POLR1B,ORC3,RNF5,PPAN,RPRD1A,PRKDC,ABCF2,RANGAP1,PCGF1,API5,DDX23,CACNB1,PDCD6,ATP6V1D,E2F1,RBPJ,TAF12,NUP188,MAX,H2AFZ,CXXC1,AP3M2,CUL1,USP39,UBE2I,PARK7,NOL11,TRA2B,SUCLG2,AP2B1,CISD2,TAF5L,SMARCE1,CDC5L,SRP72,SGCE,NSUN2,SUPT20H,USP22,RFC2,CLNS1A,EIF3A,PRIM1,DOT1L,HHEX,KIF18B,RPS14,LUC7L3,MRPL27,MAP4,SLF1,PRPF38B,COX5B,POLR2K,PRKAA1,GSPT2,RRM1,PXMP2,CYCS,SUPT7L,PRPF39,PSEN1,VPS25,NDUFS7,YY1AP1,CNOT3,NPLOC4,SPAG5,TMEM250,RPN1,EXOSC7,KLHL5,ARPC5,LRRC8D,ZNRF2,PPP4R1,MSH2,FBXL7,MRPL40,CYC1,TNRC18,APOL1,EIF5A,PIGT,PRIM2,ELL2,WDR1,RPS24,EXOSC9,ARID1A,CAPZA2,ADRB2,FXR1,GOSR1,CCT8,TWISTNB,PHF6,XRCC5,PI4K2A,DERL1,SEC31A,PFDN5,EPOP,RBMX,MED15,APPL2,NDC1,TP53RK,BCL2L1,C2orf49,CCNA2,SIAH1,RALB,ADCY9,MRPS27,TAP2,RNASEH2A,AQR,CDK12,SAP30,VDAC2,LRRC8A,ELP4,EDF1,ERC1,SERP1,TRIM28,SUPT16H,EIF3K,ANKZF1,RAD51C,CHMP4A,DSN1,DDOST,HINT1,DGCR8,NCLN,XRCC4,DYNC1LI2,PRPF4B,NDUFS1,DEPDC1,SLC41A1,MECP2,CBLL1,SPDL1,HLA-A,WWP2,CCNK,NDUFA2,ELP5,PTPN11,AXIN2,MRPL54,RPL19,CITED2,NDUFA3,MSH6,KAT2A,FBXO9,BMS1,KCNQ1,KIF11,FADD,MYO1F,RPL32,PPP1R11,DDX5,NDUFS5,WDR62,TAF6,PURA,DDB1,IPO4,RORB,POLA2,CCNC,NAT9,COPA,KMT2E,UQCR10,ATP5PF,MRPL19,SF3B2,CDC42,GOT2,JAZF1,GPATCH1,TCEA1,CARMIL1,CARM1,WDR41,DEAF1,LARS,SNRNP200,NCK1,VHL,RIOX2,TMEM216,SREK1,KMT2C,ASF1B,RPL37,HSPB11,EIF4ENIF1,NIP7,CRCP,CAB39,STK11,CLU,VPS4A,MRPL13,ATP6V0E1,DCAF5,NSMCE4A,PPP1R2,PPP1R12A,ZCCHC8,UBXN1,NACA,RPL15,THRAP3,PRPF18,NUP205,DTL,MED10,PYURF,ORAI1,ATP6V0D1,ATP5IF1,POLR2I,CREG1,ERLIN1,RPL6,EIF2A,SYVN1,EVC2,KLHL15,SNRNP70,TOB1,N4BP2L2,TCF12,SNX27,CHMP2A,PRKAB1,PMS2,SMARCA4,ORC1,CLCC1,EXT2,HNRNPA2B1,SAP130,IARS,CD3EAP,NVL,KIF14,EXOSC1,CLTB,UTP4,DNAL4,POU2AF1,UBQLN4,NXT1,PGGT1B,SMU1,PCGF6,ATXN1,LSM8,BICD2,OGDH,TOLLIP,MBD3,FANCE,RPS9,PDHX,HNRNPR,HPS5,ARNTL,ANP32E,MAPK1,ABCA1,TMEM33,GCLM,SHPRH,RAE1,SCYL1,DCTN2,NUP54,MYO9B,DCUN1D4,FERMT3,KIF5B,FGFR3,MZT2A,KLHL20,SEC24C,RRBP1,NABP2,H2AFY,ARHGEF2,ATG13,NDUFS8,FBL,STAT3,MYO5A,TXNL1,PPP1R9B,DCAF6,HELB,MIER1,RFFL,COG1,RCOR1,PRMT2,UPF1,ELMO1,KMT2B,CENPT,TERF1,ZSWIM6,TMED7,ADD1,MRPS15,PIGQ,DHX8,MIS12,PABPC4,CDK5,CALM2,PSMD1,NEK6,NSRP1,NUP153,KCNAB2,MLST8,TMEM115,MRPL43,MCL1,TOPORS,DCUN1D5,SMC2,STOML2,BRMS1,AXIN1,VIPAS39,ATP6V0C,FBXL3,TFDP2,E2F2,AAAS,NDUFV2,MRPL9,MRPS2,STRN4,TOP2B,TMED3,EZH1,ITGB5,MCTS1,EIF2S2,INTS7,MCM5,ZNF326,RTCB,CYFIP1,TIMM8B,ETV3,RB1CC1,DHX29,TEX10,MYBL2,RPS10,ABCF1,POLR2J,PTAR1,CNOT6,NDE1,RNF139,SGF29,ZNF207,SARNP,TRERF1,IVNS1ABP,UBR2,ACTR3,MON1B,MYH9,NUF2,PRKACA,STAM,APP,ANKIB1,CLUAP1,SP100,ATP2A2,UTP18,GRSF1,DDA1,NUP107,ANAPC7,RNF19A,DCTN1,ADCY7,ATP6V1G1,SHOC2,RNPS1,ATP6V0A1,DNAJA1,NDUFA7,CHCHD3,TAF2,CDC16,PEX5,HIPK2,RPLP1,TICAM1,FUS,LRP8,RPS2,SESTD1,GMCL1,UBE4A,AKT1S1,ETS1,KRI1,ERH,GATC,NDUFB4,PPP1R8,PRDM4,DCP1A,GEMIN6,SGCB,HNRNPM,PPP3CA,MRPS10,PDE3B,DDX39A,RPA1,KEAP1,KIF18A,POLE,PITX1,MAPK6,HMGB2,ANAPC4,FAF1,SNAPIN,COX15,THOC1,PPP1R15B,MCCC1,CSNK2A1,EBNA1BP2,BIRC2,LIN9,PCNA,XRCC2,PIK3R2,FAM86C1,MCMBP,MRPL32,CDC37,SP3,METTL1,EXOSC6,BAZ2A,MRPL12,EZR,LRP5,BRCA1,PRKRA,STX16,RHEB,DPYSL3,EPB41,SEPT1,TIMM13,TONSL,QRSL1,ACTB,OSGEPL1,SINHCAF,GEMIN7,RACGAP1,PPP3CB,ASXL2,SNRNP25,RB1,MED8,TIMELESS,AFF1,MAML1,TRAPPC9,RTF1,UBE4B,ARPC1A,EIF4G2,PSMC4,SYNCRIP,CDC27,SNAP23,PRPS2,TBPL1,ATP5F1A,NDUFA5,XAB2,DYNLL1,MRPL39,COPE,RPL11,RAD23A,CSDE1,SEC11A,ATP6V0B,PDK2,MDM2,MRPL34,CORO1A,SAP30L,GM2A,RPL29,RPL35,PSMA8,TUBGCP5,SLC26A6,NFATC2,PRPF3,KDM1B,TXNL4A,RPSA,SRSF1,DNAJC10,MRPL2,ATP1A1,SCAP,TOMM6,TIMM17A,PSMD3,NDUFA11,NCOA1,AP2S1,INTS2,CTDP1,CDC40,RRP15,CDT1,SMC6,GGA2,CSNK1A1,AP3S1,TFRC,IRF4,NDUFV1,CWC27,SS18L1,PTGES3,CENPM,RPAP3,SNX2,PPWD1,CHCHD6,KPNA4,GOLGA7,BIRC5,SNAP29,PGRMC1,PKD2,SPCS3,UBE2C,CHMP7,GCSH,NDUFB6,TAP1,PLXNA1,CCNB1,RIC1,POLR3K,UTP25,KIFC1,SNUPN,SPTSSA,SEH1L,AKT2,GNG7,ELOA,MRNIP,DDX20,AURKB,CCNF,SLC25A5,FOXRED1,MAK16,STT3A,TMED10,PSMD8,EIF2D,WDR4,ITGB1,DHTKD1,UQCRH,RRS1,TRAF5,HDAC2,SVIP,PPIB,HSPH1,LIME1,HLA-E,CHTF18,KIF23,NDUFA4,NOTCH2,PMF1,METTL3,COPG2,NDUFS4,CFLAR,FKBP1A,DAD1,HDAC7,ATP6V0A2,GNAI2,EEF1D,TERF2,DDX28,FTL,PHF10,SEPT8,CYFIP2,TOMM40,PKM,PATL1,SF3A2,PSMB3,FAS,EPRS,QARS,ACLY,PPP3R1,DCAF11,MAP3K5,YY1,CDK2,RNF14,RWDD1,SUZ12,SF3B1,EIF3D,RAC1,MAGED1,KLHL18,AP1B1,GNB2,SDHA,TERF2IP,PHC2,SHC1,UCHL5,CDKN1B,NAA35,GPX4,CCT2,RFC3,CUL3,SLBP,CDC23,GAR1,H2AFV,AP4E1,PSMB9,CENPU,NSA2,PPP2R5A,MRPL55,GUCY1B1,FAAP100,TBL3,SEL1L,STAT1,H2AFX,TRIM32,PDCD11,POU3F2,NCOR2,R3HCC1L,TCF3,BABAM1,BRAP,SDF2L1,RAB11A,FOXO3,MAD2L2,GTF2F1,MAT2B,RBM17,RPL17,CENPJ,COPS7B,UPF2,OSTC,CREB1,CNOT6L,IFT46,NCOA2,SMC4,ZFP64,RNASEH2C,DENND4C,WDR18,RPL8,PARP4,ILF3,ANAPC2,RPL27A,POLR2A,FBXO21,GNA12,HGS,PRDX3,PFDN4,ATP5MC3,HNRNPH3,TFDP1,STX18,KHSRP,CPEB2,VPS29,BYSL,MIB2,SKA3,PLXNC1,ST13,HNRNPAB,DCAF15,SIRT2,AGFG1,TAF6L,KIF2C,SNRPD3,BECN1,SNAPC4,EDC3,CMSS1,RAP1A,EIF4A3,AP3S2,ATG3,ZNHIT6,METTL14,KHDC4,NDUFB9,KIF22,OGG1,ARID4A,TIMM50,ELOF1,COPS8,DPM1,RRM2,WDR82,SOX4,DHX15,CHAF1A,GEMIN5,PAF1,TIMM29,PQBP1,ATXN2L,ROCK1,COPS6,RPS26,PSMC1,RPS15,ZNF768,MED13L,TIA1,MEF2A,XPO7,SRRT,NFATC3,CAPZA1,BUD31,ZNF335,YBX1,BCL2,KIFAP3,KNTC1,UBE3C,HP1BP3,CIC,PSMA1,SEPT7,CAND1,GNAS,TSC1,RBM25,CDCA5,ODF2,EXOC4,NUP62,NAA20,RBBP4,MZT2B,PDSS2,SMARCD1,WASF2,IMMT,TOMM20,MPHOSPH8,MEAF6,FARSA,BABAM2,SAR1A,RPN2,CHTOP,APOOL,PDIA6,ABI1,HTRA2,RLIM,PSMB7,DMAC2,BUD13,NDUFB1,PEF1,EIF3G,BTBD1,DAP3,CHCHD1,TULP3,WDR59,PPP2R2D,CBX4,KIF3B,MRPL42,EYA1,MRPS26,DBF4,TIMM21,CTNNBL1,TANK,MRPL11,SAMD4B,GINS1,TELO2,GTF3C6,NASP,PRKAR1B,POLR3GL,MEN1,ATP5MF,SYMPK,SNRPA,HSPA1B,MAPK3,CNOT9,HLA-B,KBTBD7,COX8A,ATP6V1C1 |
| 9.241e-65 | -147.44 | DIAZ_CHRONIC_MEYLOGENOUS_LEUKEMIA_UP | MSigDB lists | DIAZ_CHRONIC_MEYLOGENOUS_LEUKEMIA_UP | 1329 | 437 | 17377 | 2626 |
PDCD6IP,TXN,TSC2,NDUFB6,MRPS15,AGPAT1,GLUD1,OAT,EIF1B,PSMD1,ASAP2,SRSF4,RAB4A,RAD23B,DNM2,FBXW2,NUP153,ECD,TFG,MLST8,SRSF10,CDC5L,SRP72,HNRNPF,TOPORS,SMC2,USP22,ICMT,CBFB,ARF4,CLNS1A,EIF3A,STOML2,SMAD2,WDR11,PSMD8,LUC7L3,EIF2D,PTPN7,MPV17,TFDP2,RTN3,NMD3,PFKP,SMNDC1,PDCD4,HDAC2,PTOV1,WSB2,HSPH1,NDUFV2,MUT,POLR2K,DHX9,CYCS,TMED3,TMEM165,COPB2,LMNA,NDUFS4,CFLAR,GNS,CD59,EIF2S2,SMC3,RNFT1,HDAC7,DAD1,ATIC,FBXO7,PPP4R1,DAPK1,MSH2,TNPO3,PCYT2,CYC1,GEMIN4,TMED2,FDFT1,IFRD1,SIGMAR1,WDR1,ZMYND11,GTPBP4,MFNG,ITM2A,DCTD,SRSF5,CAPZA2,EIF4H,MAP2K2,MATR3,CCT8,MTR,AKAP1,XRCC5,FAS,ADSS,SEC31A,SCARB2,SLCO4A1,MTHFD2,FNTA,ETS2,ERGIC3,ACLY,MDH1,MAP3K5,YY1,RNF14,CDK2,PDLIM5,MRPL3,NUDT3,RHOG,ZNF207,KARS,CAST,ACTR3,CHD1L,UROD,RAC1,NIT2,BCL2L1,ZNF267,STAM,GNB2,CPNE3,KTN1,TERF2IP,CRKL,DECR1,PRKD3,ATP2A2,RALB,UCHL5,MTA1,DUT,GRSF1,NUP107,TP53BP2,ATF2,ARL5A,TMBIM1,CGGBP1,ADCY7,CCT2,RFC3,MAPRE2,HMGN4,CDC123,EID1,DRAP1,MAP4K4,NARF,SLBP,CDC23,H2AFV,GAR1,FKBP3,SUPT16H,TAF2,KIF2A,PPP2CA,CDC16,PPP2R5A,ACYP1,CORO1C,PPA2,RBMS1,SNRPG,COIL,CSNK1D,PKP4,GMCL1,LANCL1,UBE4A,FOXO3,RAB11A,FAM8A1,HMG20A,WRB,PNO1,GTF2F1,MAT2B,RPA2,PSMD2,PDCD10,CLIC4,PPP1R8,FEM1B,TAGLN2,NAP1L4,CITED2,MTX2,UBE2M,S100A6,MSH6,TMX1,SMC4,NUDC,LDHB,PPP3CA,STAU1,GALC,NET1,ILF3,TBRG4,EMP3,HEBP2,PICALM,TTC33,RPA1,CBX3,KEAP1,PFDN4,PRDX3,CCDC6,MFAP1,CAPN7,OAZ2,TFDP1,KHSRP,ASNA1,DUSP11,TAF6,DDB1,COX15,HNRNPAB,PLXNC1,ST13,COPA,WDR13,ENSA,CSNK2A1,SLC29A1,TAF6L,SNRPD3,UBQLN2,MAP1LC3B,BECN1,KCMF1,BIRC2,SSR1,MBD4,RAP1A,GOT2,HADHB,SRI,KIF22,RP2,TCEA1,EIF5,RYBP,SRPK2,CDC37,COPS8,DEAF1,DPM1,NCK1,TLK1,GMFB,PSMG1,BRCA1,PITPNB,UTP3,PRKRA,ODC1,USP21,DHX15,EPB41,MAN2A2,UBTF,ALG3,EIF4ENIF1,SH3GLB2,CAB39,STK11,CHPT1,PSMC1,ATP6V0E1,SEPHS2,UBE2D3,PIGN,PPP1R12A,PHB2,LAMTOR3,TIA1,CTCF,SUB1,NFATC3,EI24,RBM3,KIFAP3,GLE1,ACAD8,TMEM8A,ALDH18A1,CSNK1G3,ALDH9A1,ABCC1,HP1BP3,NIPSNAP1,CREG1,NQO2,AMD1,LDB1,PSMA1,KRAS,EIF2AK1,UBE4B,SEPT7,LY6E,ARPC1A,EIF4G2,NMT2,GALNT2,PCM1,CDC27,SNAP23,SIAH2,TBPL1,SLC16A1,PITPNA,YWHAZ,RBBP4,TCF12,PRKAB1,GLT8D1,NDUFA5,IMMT,FEZ2,TOMM20,SUCLG1,UGP2,CHERP,MDH2,SLC2A1,TM9SF3,ATP6V1B2,LYN,PAIP1,CSDE1,SEC11A,ZNF302,TNFAIP8,WDR44,PPP6C,PDCD2,BCAP29,TARDBP,RPN2,MINPP1,LMAN1,AHCYL1,F2R,ABI1,STRAP,GM2A,HTRA2,EBAG9,PRPF19,ACSL5,KDM3B,CLPTM1,SELPLG,CPOX,PPIE,ATXN1,WIPF1,GLO1,OGDH,PEF1,PDHX,BTBD1,SRSF1,IDE,ATP1A1,HNRNPR,TIMM17A,PSMD3,FKBP5,NCOA1,GAS2,USP11,MAPK1,SMAD4,ZNF146,MIF,SLC30A9,GCLM,CMAS,TRIP12,CASP6,PDAP1,DBF4,NUP54,CHIC2,ARF1,CSNK1A1,TFRC,GART,CTNNBL1,ANP32A,BRD7,CLDND1,PTGES3,STAT3,RNF5,TGFB1,TXNL1,YTHDC1,ELOVL5,PRKDC,ATP2C1,ABCF2,RANGAP1,MEN1,API5,TARS,ZFR,DDX23,KPNA4,UPF1,PDCD6,SEC23IP,PLAA,TWSG1,PGRMC1,ACAT1,ACADM,RBPJ,SRSF3,IDH3B,RPS6KC1,TERF1,GCSH |
| 6.105e-64 | -145.56 | nitrogen compound metabolic process | biological process | GO:0006807 | 8460 | 1681 | 17256 | 2622 |
ZBTB10,HEXB,TGOLN2,LACTB2,CCNL2,RBM4,ZNF275,FBXO22,EEF2K,RPL23A,USF1,RAD23B,UPRT,CRY2,ECD,RNF26,ZNRD1,TIPARP,ANKRD9,MGAT5,RHBDD2,FTSJ3,MRPL57,USP34,BAK1,ERCC1,ZNF559,NRAS,GABPA,EHMT1,HNRNPF,WDHD1,MIER2,DIDO1,MCM2,ARF4,GINS4,SMAD2,RAD18,RPS27A,MYO18A,OGT,COX5A,RNASEL,KLHL42,SMAD1,CHPF2,ZNF75A,OAZ1,SMNDC1,SLC25A33,ZNF720,HIVEP3,CLSPN,GGA1,MUM1,TRIO,DHX9,RAB23,KCTD17,EIF2AK4,PDCD7,PSMD9,APH1B,PARN,CDC73,ATG4A,TFAP4,PDXP,SMC3,RNFT1,FBXO7,EFTUD2,GEMIN4,MRPL21,CPSF4,NUP85,PABPC1,PHKG2,NSUN4,PPA1,LUC7L2,SRSF11,EIF3L,AGGF1,FOXK1,MAPKAPK3,MTA2,SF3B6,ERO1A,TYW1,GTPBP4,USP10,BCLAF1,MRPL16,ELK1,EIF4H,FNTA,KPNA1,ETS2,TYW5,WIPI2,ZNF830,CFAP20,NUP58,MRPL3,TRIM41,KARS,NQO1,PTTG1,STARD7,SLC35B2,INO80E,GLRX3,RCOR3,CPNE3,RBM23,FBXL6,ZNF420,MTA1,UBA5,GMEB1,NABP1,NSFL1C,INTS12,ZNF226,GPD1L,ZC3H3,RPRD1B,CGGBP1,PDCL3,CPNE1,ULK3,SEC61B,ERMP1,POLR2L,EID1,KAT7,CRNKL1,RPL38,E2F3,POLR2D,MEF2D,RAB1A,PPP2CA,ALDH3B1,LSM6,NSMCE2,CAMKMT,RNF38,DMWD,SNRPG,PPP5C,PITRM1,USP13,COMMD10,ZNF445,SRSF6,ZFP91,TRMT6,CCM2,HABP4,ABHD14B,ATP5F1B,WDR5,NEXMIF,RRP36,NEIL2,TUT4,PPP1R3B,GOLM1,RPA2,ZBTB45,PSMD2,CLIC4,ITGB8,HUWE1,ZNF260,NAA50,LTN1,KANSL2,UBE3B,ST8SIA2,ZNF710,GTF2H2,FBXL19,RPL22L1,MED22,SPTAN1,DDX24,USP42,LDHA,UTP20,SLC19A1,MAGT1,GPS2,PARG,DBI,AEN,PARP10,WDR45B,THAP5,TRIM11,YTHDC2,RBM8A,SND1,FANCI,PAPOLA,ZER1,KRR1,CREM,TET3,FANCL,RAB8A,NUP210,GLIS2,INTS1,SLC44A1,POP7,NOC2L,EIF5,MTPN,ASB6,RYBP,PLK1,RPP25,PTPN18,RBX1,APH1A,RAD51AP1,SNRPB,CDC6,UBE2V1,PBRM1,EAF2,UTP3,KRTCAP2,ODC1,LUC7L,USP21,ALG3,TRIM4,CHD3,ZNF367,E2F4,ARRDC1,ADAM9,PRPF4,KPNA2,DVL1,CLN3,BEND6,FAM208A,NGLY1,POT1,ZNF564,FUBP1,RMND5A,CTU2,ZCCHC9,PHB2,CENPF,LAMTOR3,SDC2,CHCHD2,COX4I1,ADCK5,CDK13,RAB6A,CNOT11,RSAD1,ARID1B,C1GALT1,SUB1,MLX,UBE2Q2,CCP110,MBD2,SSBP3,XPA,ZNF746,CTR9,AHCY,RBM3,ICE2,MRPL48,LRSAM1,DCAF8,LDB1,AMD1,MAP4K3,ZNF761,METTL22,ARMC8,STYXL1,RBM38,NMT2,IRF5,RXRB,RPL36,PAXX,MBIP,GALNT2,ORMDL2,COX7A2L,ZDHHC7,DTD1,RUVBL2,ECPAS,BCCIP,USP7,SART1,TRAF7,RPLP2,SUCLG1,ARID2,LAGE3,ZNF416,RRAGC,ATP6V1B2,LYN,PCBP1,ZNF121,MRPL50,NRF1,PSMA6,ZNF473,KMT5C,BRPF3,ZNF302,ABRAXAS2,PIN1,PPME1,RPAP1,TARDBP,LMAN1,TOP1MT,AHCYL1,STRAP,SPIDR,CTDSP2,SPSB3,ZNF583,PRPF19,PPIF,KDM3B,MND1,BIRC3,POLR2G,ZNF780B,PPT1,RAB7A,PPIE,NUP155,DCLRE1C,MRPS14,RHBDF2,EIF3H,SUGP1,IDE,DHX16,RBL1,UBXN2B,FASTK,STK38,UHRF2,CHMP4B,XRCC3,H3F3A,CHID1,SMAD4,RAD51D,SLC30A9,NADSYN1,NIFK,MCM10,MTERF1,KLHL21,AGO2,TMX3,CDCA8,GTF3A,CDK11B,PAGR1,SCYL2,DNAJB9,HERC3,GTPBP3,CTSS,POLR1B,ORC3,RNLS,RNF5,RBM15B,YTHDC1,RHOA,RPRD1A,HMGN5,PRKDC,TUFM,TOP3A,RANGAP1,PNPLA8,PCGF1,HAGH,DDX23,PDCD6,NEK1,L3MBTL3,NEIL3,CTBS,BBX,E2F1,IMPDH1,USP20,RBPJ,TAF12,NR2F2,PGAM1,HIPK3,IFI16,TXN,NUP188,MAX,PDCD6IP,GXYLT1,ADAM10,PRKCSH,CXXC1,CUL1,USP39,NANS,UBE2I,OAT,MYEF2,PARK7,ASPHD2,PA2G4,NOL11,FIZ1,ZNF200,TRA2B,FBXW2,AP2B1,TAF5L,SLC26A2,MARCH2,ZNF800,CDC5L,SRSF10,ZNF524,KLF10,NSUN2,LACTB,USP22,CBFB,RFC2,CLNS1A,EIF3A,PRIM1,DOT1L,IWS1,MAP3K4,HHEX,MKNK1,BRD2,RPS14,TPP2,LUC7L3,MRPL27,BTF3,PTPDC1,SLF1,CCDC59,B4GALT2,PTOV1,PRPF38B,RECQL,COX5B,EWSR1,DHPS,POLR2K,GSPT2,PRKAA1,RRM1,TATDN3,B4GALT1,CYCS,SUPT7L,PRPF39,ZNF79,ZNF518A,PSEN1,TMEM165,VPS25,NDUFS7,YY1AP1,NPLOC4,CNOT3,WDR48,RPN1,LHX8,EXOSC7,KLHL5,ZNRF2,PPP4R1,MSH2,DAPK1,TPST1,PIGG,FBXL7,MRPL40,CYC1,MRM3,APOL1,SOCS5,EIF5A,PIGT,PRIM2,CPQ,ELL2,COQ8A,USF3,MFNG,ZNF574,RPS24,EXOSC9,ARID1A,ADRB2,MTR,MAP2K2,TWISTNB,PHF6,XRCC5,DERL1,CAT,MTHFD2,GOLGA2,EPOP,RBMX,MED15,PIAS2,USP32,CEBPG,SAMD8,SMPD4,GPI,NUDT3,ZNF511,NDC1,ATXN3,TP53RK,RAB11B,RAF1,UROD,C2orf49,CD320,SPINDOC,CCNA2,SIAH1,MTMR4,ADCY9,LPIN2,SOCS6,MRPS27,TTC3,RNASEH2A,AQR,ILKAP,CDK12,CFL1,SAP30,BRD4,DRAP1,ELP4,EDF1,PKMYT1,ASB13,ERC1,SERP1,TRIM28,SUPT16H,AMZ2,EIF3K,ANKZF1,ZNF282,RAD51C,HINT1,DDOST,DGCR8,CERS6,SAFB,FTSJ1,ATF6,BEND3,XRCC4,EYA2,ADAM23,PRPF4B,NDUFS1,DEPDC1,B4GALT5,MANBA,MECP2,TKT,CBLL1,ARGLU1,SECISBP2,POFUT1,HMG20A,WWP2,RFWD3,CCNK,DNAJC8,NDUFA2,ELP5,FUT8,PTPN11,AXIN2,MRPL54,FEM1B,RPL19,CARF,CITED2,NDUFA3,MSH6,KAT2A,LONRF3,RFXANK,ADSL,FBXO9,BMS1,KCNQ1,OTUD3,ARSK,GUF1,COMMD4,KLF6,SPPL2B,FADD,CBX3,RPL32,ZHX1,OAZ2,PPP1R11,DUSP11,DDX5,NDUFS5,WDR62,WDR91,TAF6,ESPL1,PURA,DDB1,RORB,POLA2,CCNC,ZNF76,PIGM,KMT2E,UQCR10,PHRF1,UBE2Q1,PTP4A3,COMMD5,ATP5PF,MRPL19,ZNF696,SF3B2,PCYOX1L,CDC42,GOT2,JAZF1,RPF2,GPATCH1,TCEA1,SLC35C2,CARMIL1,CARM1,SRPK2,DEAF1,LARS,SNRNP200,NCK1,LAP3,VHL,RIOX2,SREK1,SUMF2,KMT2C,PRPSAP1,MPC1,ASF1B,RPL37,MAN2A2,BRWD1,U2SURP,PPM1G,CRCP,CAB39,BAZ1B,STK11,ZNF268,CHEK2,CLU,VPS4A,CHPT1,MRPL13,DCAF5,CAPN1,UBE2D3,NSMCE4A,PPP1R12A,ZCCHC8,GORASP1,NACA,UBXN1,PCSK7,RPL15,PM20D2,THRAP3,XPNPEP3,TTF1,NUP205,PRPF18,CHKA,LYAR,DTL,MED10,PYURF,TENM3,ZRANB1,CSNK1G3,ATP5IF1,POLR2I,ERLIN1,NUDT4,SUGP2,RPL6,GBA,SYVN1,EIF2A,VKORC1,SLTM,DAPK3,MASTL,UAP1,KLHL15,NFIL3,SIAH2,FN3KRP,CTSA,DNPH1,SNRNP70,APOL2,TSEN15,ADNP2,TCF12,PRKAB1,MDH2,PMS2,UCK2,SMARCA4,UCK1,ORC1,EXT2,MXD1,USP5,HNRNPA2B1,SAP130,RRN3,UBXN2A,IARS,CD3EAP,KIF14,EXOSC1,PPP6C,UTP4,ZNF770,CSTF1,CHP1,POU2AF1,HPDL,PGGT1B,RNF25,METTL2A,SMU1,PCGF6,ATXN1,LSM8,GLO1,OGDH,EDEM2,TOLLIP,MBD3,FANCE,RPS9,PDHX,DUS3L,HNRNPR,STAT6,ARNTL,FKBP5,BRD9,MAPK1,ABCA1,CWC25,PDF,NAT14,DNAJC2,GCLM,TRIP12,ZNF316,SHPRH,RAE1,SCYL1,NUP54,PAWR,MXD4,DCUN1D4,GFM2,SPPL2A,FASTKD3,FGFR3,GRK2,KLHL20,KMT5A,PPIG,RRBP1,NABP2,DUS2,ANP32A,NDUFS8,FBL,ERI3,STAT3,SLC35A1,AMPD2,B3GALT6,TGFB1,ELOVL5,PPP1R9B,DCAF6,HEMK1,HELB,PSPC1,MIER1,NADK2,RFFL,RCOR1,PRMT2,CDK11A,TFEB,MTMR3,CTSL,UPF1,ZC3H7B,DTX4,KMT2B,ACAT1,ZMIZ1,PLOD3,HRAS,SLF2,TERF1,FGFR1OP,ADD1,KDM4A,MRPS15,MAP3K7CL,PIGQ,XIAP,DHX8,GLUD1,EDRF1,PABPC4,CDK5,PSMD1,CIPC,NEK6,NSRP1,SRSF4,PDS5B,FNIP2,NUP153,SENP1,KCNAB2,PCBP2,PGAP2,PLK3,ZNF672,TMEM115,MRPL43,TOPORS,DCUN1D5,ICMT,STOML2,BRMS1,ZNF689,AXIN1,LIMK1,ATE1,VIPAS39,ST3GAL2,SMG9,FBXL3,TFDP2,E2F2,LONP2,AAAS,PFKP,DDX42,SSRP1,NDUFV2,MRPL9,MRPS2,CERK,TOP2B,EZH1,ZNRF3,MCTS1,RAVER2,DDRGK1,GNS,DDX56,EIF2S2,INTS7,MCM5,RTCB,ZNF326,FOXN2,CARS2,UBE2QL1,NAGPA,ETV3,RB1CC1,DHX29,ZMYND11,MAN1B1,TEX10,MYBL2,RPS10,ARMT1,SRSF5,CBFA2T2,MPG,ABCF1,PTPRF,POLR2J,DUSP3,CSK,SETD3,TEX30,PTAR1,MDH1,CNOT6,HEXA,SGF29,RNF139,EGLN1,ZNF296,SARNP,ABCA3,TRERF1,IVNS1ABP,UBR2,CHD1L,RMI2,WDTC1,MYH9,CREBL2,NIT2,RXYLT1,EFL1,ZNF267,SAFB2,PRKACA,TCF19,STAM,APP,KTN1,ANKIB1,PRKD3,SP100,ZKSCAN1,UTP18,DUT,GRSF1,DDA1,NUP107,ANAPC7,MAVS,RNF19A,ATF2,RBM15,CLN6,RNF169,ADCY7,ENPP4,INTS13,MAP4K4,RNPS1,WBP2,ATP6V0A1,NDUFA7,TAZ,FKBP3,DDX17,TAF2,CHCHD3,PEX5,CDC16,NT5C3B,HIPK2,RPLP1,RBMS1,MBOAT1,FUS,PDXK,GEN1,ZBTB11,LRP8,GALK1,ZNF786,RPS2,TRAK1,JMJD6,UBE4A,ETS1,ZNF92,PNO1,KRI1,FBXO3,CAPN2,ERH,SUV39H2,GATC,NDUFB4,PPP1R8,PRDM4,DCP1A,GTSE1,GEMIN6,TTLL12,HNRNPM,LYPLA2,LDHB,PDPK1,PPP3CA,TK1,GUK1,TNFAIP3,GALC,POLK,ZNF512,MRPS10,DDX39A,PDE3B,RPA1,ZNF862,ZNF180,KEAP1,POLE,TATDN2,PITX1,MAPK6,CAPN7,LRPPRC,PML,SLC25A19,HMGB2,PSAP,USF2,ANAPC4,FAF1,SNAPIN,SRM,COX15,DDX47,THOC1,AGRN,GNPDA1,GPBP1L1,PPP1R15B,MCCC1,CSNK2A1,EBNA1BP2,BIRC2,LIN9,ABL2,PCNA,ZNF639,ETV6,TRMU,XRCC2,PPCDC,MCMBP,MYBL1,MRPL32,CCAR1,ABCC5,PTPRK,CDC37,SP3,METTL1,EXOSC6,BAZ2A,HARS,TLK1,MRPL12,GMFB,BRCA1,ESYT1,PRKRA,TONSL,NAGLU,SOCS4,QRSL1,ACTB,DHFR2,OSGEPL1,ZNF45,NUDT11,NAA60,GEMIN7,SEPHS2,TMUB1,ASAH1,CTCF,PPP3CB,B4GALT4,RLF,ASXL2,SNRNP25,RB1,NUS1,MED8,CMTR2,PPIL2,TIMELESS,MDFIC,MAML1,ALDH18A1,PREB,ABCC1,UTP15,KRAS,RTF1,EIF2AK1,UBE4B,NFATC2IP,LY6E,EIF4G2,ZDHHC3,ZNF174,PSMC4,SYNCRIP,PALB2,CDC27,PRPS2,TBPL1,PRMT7,ATP5F1A,RNF114,KCTD7,NDUFA5,CYLD,UGP2,FOXM1,MRPL39,XAB2,DYNLL1,SUMO2,DUSP22,RPAIN,COMMD8,RPL11,RAD23A,SEC11A,CSDE1,PDK2,ZBTB21,MDM2,DUS4L,MRPL34,MINPP1,SAP30L,GM2A,DVL2,RPL29,RPL35,PSMA8,BTG2,CPOX,MTMR6,NFATC2,PRPF3,KDM1B,TXNL4A,USP36,RPSA,SRSF1,DNAJC10,MRPL2,CLK3,ZNF700,MAFK,PSMD3,NDUFA11,ZNF436,DNAJC17,NCOA1,LTA4H,AP2S1,SLC25A39,USP53,ZC3HC1,INTS2,CTDP1,CDC40,RRP15,CDT1,GNE,ARID5A,SMC6,NKRF,SUMF1,CHAC2,GGA2,CSNK1A1,RMI1,WRNIP1,PTPN2,IRF4,GSTK1,NDUFV1,CWC27,SS18L1,DDX31,PTGES3,CAMK2G,CNTN5,ZNF202,ZMYM5,PPWD1,NEU1,FBXO41,GOLGA7,BIRC5,TFE3,CDCA7L,ACADM,SPCS3,RPS6KC1,UBE2C,SAT2,GCSH,ZNF496,PPCS,NDUFB6,ZDHHC8,NHLRC3,CCNB1,EIF1B,COMMD6,POLR3K,UTP25,SNUPN,PARPBP,RNASEK,CDC25B,MAST2,SPTSSA,DNMT1,SEH1L,AKT2,PBK,NOL8,ELOA,MRNIP,DDX20,GALNT7,AMDHD2,AURKB,CCNF,MCFD2,MAK16,RBM47,STT3A,PSMD8,WDR4,EIF2D,PTPN7,DHTKD1,UQCRH,RRS1,ARRB2,ZNF598,HDAC2,DDX58,WSB2,PPIB,LIME1,MUT,GMFG,CHTF18,ADO,NDUFA4,MAN2B1,NOTCH2,PMF1,METTL3,JMY,CFLAR,NDUFS4,FKBP1A,RNF121,KLF16,HDAC7,ATIC,DAD1,CTPS1,ATP6V0A2,RNF135,LPCAT1,EEF1D,TERF2,MORC3,PHF10,DDX28,ZNF84,NOA1,DCTD,PKM,CYFIP2,KDM3A,PATL1,SF3A2,PSMB3,ADSS,EPRS,ZNF777,SERTAD2,ZFP92,QARS,DCK,CSNK1G1,ACLY,LPCAT4,PPP3R1,DCAF11,VCPIP1,YY1,MAP3K5,RNF14,CDK2,NRBP1,ZC3HAV1,DNMT3A,RWDD1,ZBTB37,RPS6KA1,SF3B1,SUZ12,EIF3D,RAC1,OLA1,KLHL18,ADPGK,SDHA,SDE2,TERF2IP,CRKL,FLAD1,APLP2,ZNF75D,SHC1,KDM2A,UCHL5,TALDO1,NAA35,MRM2,RFC3,ERF,TAOK1,CUL3,SLBP,KIAA1586,CDC23,POLG2,GAR1,PSMB9,DHX57,CENPU,PRDM11,SOCS7,NSA2,VEZF1,PPP2R5A,MRPL55,JAK1,TBL3,GUCY1B1,FAAP100,STAT1,SEL1L,PPA2,H2AFX,TRIM32,B4GALT3,PDCD11,ATMIN,CSNK1D,POLQ,OTUD5,POU3F2,NCOR2,TWNK,TCF3,MRI1,BABAM1,CDCA3,BRAP,MYNN,SDF2L1,BLM,SPR,RAB11A,FOXO3,MAD2L2,GTF2F1,RBM17,RPL17,PTEN,CRAT,COPS7B,UPF2,CNOT6L,OSTC,CREB1,MAP3K14,UBE2M,NCOA2,TSHZ1,ZFP64,RNASEH2C,NEK7,TRIR,WDR18,PARP4,ILF3,RPL8,TBRG4,ANAPC2,RHOT1,RPL27A,MARK2,TSR2,POLR2A,FBXO21,NUCB1,SGSH,HGS,ATP5MC3,TTLL4,PRDX3,HNRNPH3,TFDP1,NAXE,KHSRP,CPEB2,BYSL,ESYT2,DDX52,MIB2,ADA2,PTMS,IER2,UBE2E2,NOP2,DCAF15,NF1,ALKBH5,MOGS,DNAJC24,ZNF107,UBE2Z,SLC29A1,TAF6L,SIRT2,SNRPD3,UBQLN2,USP48,FKBP2,MAPK14,BECN1,SNAPC4,RNF103,EDC3,BCAT2,UBLCP1,MBD4,CYREN,THADA,EIF4A3,METTL14,ATG3,IMPAD1,DPYSL2,PHTF1,SRI,AKR1B1,KHDC4,KIF22,NDUFB9,ZBTB22,JOSD1,NFU1,OGG1,ARID4A,FGFR1OP2,TIMM50,ELOF1,COPS8,TDP1,TRIM8,DPM1,RRM2,WDR82,SOX4,STK17B,DHX15,CHAF1A,PAF1,GEMIN5,UBTF,UEVLD,PQBP1,IARS2,GALNT10,ROCK1,COPS6,RPS26,PSMC1,RPS15,PIGN,ZNF768,UFC1,CIB1,MED13L,MEF2A,SRRT,RHBDD1,NFATC3,ZNF449,ZNF335,BUD31,BCL2,GLTP,YBX1,ACAD8,UBE3C,N4BP2,ZNF189,ALDH9A1,VOPP1,TSTA3,CIC,PSMA1,ISG15,CAND1,GNAS,NAP1L1,RBM25,CDCA5,NUP62,TRMT10B,ZFP90,RBBP4,NAA20,NIPSNAP2,HNRNPDL,PTDSS1,ZBTB24,MBD1,MMACHC,TOMM20,ASH1L,MPHOSPH8,GNPNAT1,CHERP,WDYHV1,PLAGL2,NSD3,CHKB,IRF3,CHD1,MEAF6,PAIP1,FARSA,ANKLE1,BABAM2,AKAP8,PARL,RPN2,CHTOP,PDIA6,ABI1,TMEM14C,SCYL3,HTRA2,RLIM,CGAS,ZNF500,PSMB7,NLN,NDUFB1,BUD13,PEF1,EIF3G,BTBD1,RAD54B,DAP3,ZNF317,TAB2,CHCHD1,CANT1,USP11,AKNA,SMURF1,TSPAN5,PPP2R2D,CBX4,SH2D3A,MRPL42,CASP6,EYA1,SRGN,MRPS26,DBF4,KLF13,HDDC2,MAN1A1,GART,CTNNBL1,PELO,TANK,BRD7,MRPL11,SAMD4B,GINS1,ZDHHC18,CSNK1G2,TELO2,GTF3C6,ADAM17,HMGN1,NASP,PRKAR1B,POLR3GL,WDR81,MEN1,ATP5MF,ZNF407,SYMPK,SNRPA,TARS,MAPK3,HSPA1B,CNOT9,ATAD2,PLAA,OSBPL8,COX8A,KBTBD7,ZRANB2,SRSF3,MBD6,TATDN1,PREPL,TYW1B |
| 7.891e-62 | -140.69 | cytoplasmic part | cellular component | GO:0044444 | 9540 | 1807 | 18223 | 2701 |
TSC2,ABCC10,HEXB,TGOLN2,LACTB2,SYNRG,CMTM6,RBM4,FBXO22,EEF2K,RPL23A,CDKN2C,NAPG,DNAAF2,RAD23B,MECR,AP1M1,DNM2,UPRT,CRY2,ECD,RNF26,MOB1A,LRRC59,ANKRD9,MGAT5,RHBDD2,MRPL57,USP34,BAK1,ERCC1,RHOBTB3,NRAS,KIF15,HNRNPF,NUTF2,COA7,RAB22A,ARF4,BOLA3,AHNAK,MID1IP1,SMAD2,RPS27A,MYO18A,OGT,MPV17,COX5A,RNASEL,KLHL42,SMAD1,CHPF2,OAZ1,ANXA11,PDCD4,SLC25A33,NXT2,CLSPN,GGA1,SEC61G,CCZ1,RHOC,MUM1,TRIO,DHX9,RAB23,KCTD17,HAUS4,EIF2AK4,PSMD9,APH1B,PARN,HAUS2,CDC73,MYL6B,COPB2,ATG4A,TMEM179B,TFAP4,CD59,PDXP,SMC3,RNFT1,RIMS3,FBXO7,EFTUD2,GEMIN4,MYDGF,MRPL21,MVP,NUP85,PABPC1,PHKG2,NSUN4,PPP6R1,PPA1,EIF3L,AGGF1,MAPKAPK3,MTFR2,ERO1A,GTPBP4,ITM2A,USP10,SSR2,MAP7D1,MRPL16,MTX1,ELK1,EIF4H,SFXN5,RDH11,MAGED2,FNTA,KPNA1,TXNDC16,PDLIM1,ETS2,WIPI2,CFAP20,RUFY3,PDLIM5,ACSF2,MRPL3,ALS2,FAM72A,FAM72D,EXOC3,RHOG,KARS,GGNBP2,NQO1,POC1A,PTTG1,ANK3,VTI1A,TPX2,STARD7,TBC1D13,SLC35B2,GLRX3,STMN1,LCLAT1,CPNE3,REPS1,AHCTF1,SH3BP1,MTA1,TBC1D14,UBA5,NABP1,CLCN6,NSFL1C,SEPT11,MICU2,GPD1L,RPRD1B,PDCL3,SNX8,CPNE1,ULK3,SEC61B,ERMP1,POLR2L,EID1,GOPC,KAT7,IDH3A,RPL38,CIRBP,POLR2D,HTATIP2,PFKFB3,GORAB,TMEM147,RAB1A,MAT2A,PPP2CA,KIF2A,ALDH3B1,VPS26B,CCDC14,LSM6,CAMKMT,SNRPG,PPP5C,PITRM1,TUBB,USP13,MZT1,TRMT6,CCM2,HABP4,FLOT1,ABHD14B,ATG2B,ATP5F1B,PMVK,IFT27,SLC25A43,SAPCD2,TUT4,SRXN1,PPP1R3B,GOLM1,PSMD2,PDCD10,CLIC4,COQ4,HUWE1,ARF5,ARHGEF1,ZNF260,NAA50,ANXA5,LTN1,KANSL2,ST8SIA2,FBXL19,RPL22L1,SPTAN1,STAU1,TCTEX1D2,MRS2,LDHA,HEBP2,RAB3IP,PICALM,SH3BP5,MAGT1,GPS2,PARG,ACOX1,DBI,FAM3C,SSNA1,PARP10,YWHAH,WDR45B,FAM129A,TRIM11,YTHDC2,RBM8A,SNX15,SND1,RUFY1,TRIM65,FANCI,PRNP,RAB8A,NUP210,TIMM23,SLC44A1,NOC2L,EIF5,MTPN,ASB6,TACC3,PLK1,PTPN18,SEPT9,MIOS,RBX1,APH1A,SNRPB,PSMG1,CKAP2L,CDC6,UBE2V1,KRTCAP2,ODC1,USP21,LSG1,NECAP2,ALG3,TRIM4,TRAM2,AGPAT2,GRIPAP1,ARRDC1,KPNA2,DVL1,DNAJC30,CLN3,NGLY1,MYL12B,NUMB,CTU2,HJURP,PHB2,DNAJB2,CENPF,NKD2,SDC2,LAMTOR3,KLC1,CHCHD2,COX4I1,CDK13,RAB6A,DNAJB1,NCKAP1,CNOT11,RSAD1,ARID1B,C1GALT1,TNS3,MLX,UBE2Q2,CCP110,RINL,MBD2,KIF13B,ARL6IP1,AHCY,ICE2,RBM3,GLE1,MRPL48,LRSAM1,NIPSNAP1,ABHD2,DCAF8,NSDHL,ACSL3,AMD1,ARMC8,APPL1,RBM38,NMT2,IRF5,BBS12,RMC1,HAUS8,RPL36,SDHB,MBIP,PCM1,GALNT2,ORMDL2,TMEM168,COX7A2L,LAMTOR4,NLRC5,ZDHHC7,SIL1,DTD1,RUVBL2,MYO9A,CCNB2,ECPAS,UNC13C,BCCIP,USP7,SART1,GLT8D1,TRAF7,RPLP2,SUCLG1,NDUFAF2,TMX4,SLC2A1,ZFYVE21,RRAGC,ATP6V1B2,LYN,PCBP1,BCAP31,OIP5,MRPL50,VAV1,NRF1,PSMA6,BRPF3,WDR44,ABRAXAS2,PIN1,BCAP29,LMAN1,TOP1MT,AHCYL1,STRAP,SPSB3,SNX25,PPIF,ARHGAP17,CLCN3,BIRC3,POLR2G,PPT1,RAB7A,PPIE,DCLRE1C,CHMP2B,VDAC1,MRPS14,RHBDF2,EIF3H,GLOD4,AFDN,IDE,UBXN2B,FASTK,STK38,AP1S1,CHMP4B,XRCC3,CHID1,SMAD4,PARD3,SLC30A9,NADSYN1,MTERF1,KLHL21,PDAP1,AGO2,TMX3,CDCA8,HMGN3,ARF1,NCAPG,SCYL2,TUBGCP2,DNAJB9,FZD6,HERC3,GTPBP3,HOMER1,CTSS,POLR1B,RNF5,ACP2,RHOA,PRKDC,ABCF2,TUFM,RANGAP1,ARHGEF12,PNPLA8,HAGH,RAB18,SEC23IP,TRIM26,PDCD6,NEK1,ATP6V1D,CTBS,BBX,E2F1,IMPDH1,USP20,NR2F2,PGAM1,ARHGAP23,HIPK3,IFI16,TXN,PDCD6IP,PNISR,TMEM203,ADAM10,PRKCSH,TSC22D3,CXXC1,AP3M2,CUL1,NANS,GYG1,UBE2I,OAT,PARK7,SLC25A37,GLMP,PA2G4,MTFR1L,RAB4A,TRA2B,FBXW2,SUCLG2,AP2B1,TAF5L,CISD2,MARCH2,CDC5L,SRSF10,SRP72,SGCE,NSUN2,LACTB,RAB2B,CLNS1A,EIF3A,MAP3K4,MKNK1,WAS,KIF18B,RPS14,TPP2,MAP4,MRPL27,BTF3,FAM72C,B4GALT2,PTOV1,COX5B,C9orf78,DNAJC5,SCOC,DHPS,POLR2K,GSPT2,PRKAA1,VAV2,RRM1,ACAP1,B4GALT1,PXMP2,CYCS,PSEN1,TMEM165,PDXDC1,VPS25,NDUFS7,WDR48,SPAG5,NPLOC4,CNOT3,RTKN,C12orf10,TMEM250,RPN1,CEP104,EXOSC7,KLHL5,ARPC5,LRRC8D,ZNRF2,TPST1,PIGG,OSTF1,FBXL7,MRPL40,CYC1,TNRC18,MRM3,SYTL3,APOL1,FDFT1,SOCS5,EIF5A,GCC2,PIGT,CPQ,COQ8A,WDR1,RDH10,USF3,MFNG,RPS24,C1orf35,EXOSC9,GORASP2,CAPZA2,ADRB2,FXR1,GOSR1,MTR,MAP2K2,CCT8,AKAP1,PI4K2A,XRCC5,DERL1,SEC31A,CAT,MTHFD2,GOLGA2,USP32,APPL2,ARAP1,CABIN1,SAMD8,SMPD4,GPI,CDKN2A,NUDT3,CYTIP,ATXN3,TP53RK,REPS2,RAB11B,RAF1,UROD,SLC39A13,POMP,BCL2L1,CD320,NUDT19,DECR1,CCNA2,SIAH1,MTMR4,RALB,ADCY9,LPIN2,SOCS6,MRPS27,BRI3,TAP2,TTC3,RNASEH2A,TP53BP2,ILKAP,CFL1,ANKLE2,BRD4,VDAC2,ABHD11,EDF1,PKMYT1,ASB13,ERC1,SERP1,EIF3K,ANKZF1,RAD51C,CHMP4A,DSN1,HINT1,DDOST,RAB24,CERS6,FTSJ1,NCLN,ATF6,XRCC4,EYA2,DYNC1LI2,NDUFS1,B4GALT5,MANBA,MECP2,TKT,CBLL1,ARGLU1,SECISBP2,SPDL1,POFUT1,HEATR5B,HLA-A,WWP2,EBP,SLC25A36,DNAJC8,NDUFA2,ELP5,FUT8,PTPN11,AXIN2,MRPL54,FEM1B,RPL19,CNN2,NDUFA3,MTX2,MSH6,KAT2A,ANKRD37,TMEM126B,RFXANK,RABIF,ADSL,FBXO9,PACS1,KCNQ1,OTUD3,ARSK,MACF1,GUF1,KLF6,KIF11,SPPL2B,FADD,SH3GLB1,SMAP2,INF2,TMEM127,RPL32,OAZ2,PPP1R11,NDUFS5,WDR62,WDR91,TAF6,ESPL1,DEF6,FAM83G,HIGD2A,GPR89B,ZBED3,POLA2,PIGM,LYRM4,MTX3,COPA,UQCR10,PTP4A3,UBE2Q1,ABCB10,COMMD5,MAP1LC3B,ATP5PF,MRPL19,PCYOX1L,DST,CDC42,SYNM,GOT2,RAB35,JAZF1,HADHB,SLC35C2,CARMIL1,DRAM2,CARM1,SRPK2,WDR41,TRAPPC13,LARS,NCK1,LAP3,VHL,LRBA,RIOX2,TMEM216,ARHGDIB,SUMF2,PITPNB,MPC1,RPL37,MAN2A2,EIF4ENIF1,BRWD1,NIP7,MIA2,SH3GLB2,CRCP,CAB39,STK11,ZNF268,CHEK2,CLU,VPS4A,CHPT1,MRPL13,ATP6V0E1,CAPN1,UBE2D3,PPP1R2,PPP1R12A,GORASP1,NACA,UBXN1,EPN1,PCSK7,RPL15,XPNPEP3,RGS2,QSOX2,TTF1,CHKA,DTL,PYURF,EI24,ZRANB1,ATP6V0D1,ATP5IF1,CREG1,ERLIN1,NUDT4,RPL6,GBA,SYVN1,EIF2A,VKORC1,ARHGAP15,UAP1,SIAH2,FN3KRP,YWHAZ,CTSA,DNPH1,EHD4,TMEM14A,APOL2,SNX27,PRKAB1,CHMP2A,CORO7,MDH2,PMS2,UCK2,UCK1,ORC1,CLCC1,EXT2,MXD1,USP5,UBXN2A,IARS,CD3EAP,KIF14,EXOSC1,PPP6C,CS,CYB5R1,CLTB,EBAG9,CHP1,UBQLN4,NXT1,RNF25,ATXN1,GLO1,BICD2,OGDH,FAM72B,EDEM2,TOLLIP,RPS9,PDHX,PON2,DUS3L,VPS26C,SURF4,HNRNPR,HPS5,STAT6,ARNTL,ANP32E,FKBP5,MAPK1,ABCA1,TMEM33,PDF,DNAJC2,GCLM,TRIP12,SCYL1,DCTN2,VPS45,CHIC2,MYO9B,PIP4K2A,GFM2,XPR1,FERMT3,SPPL2A,KIF5B,FASTKD3,FGFR3,MZT2A,GRK2,KLHL20,KMT5A,SEC24C,PPIG,RRBP1,ZDHHC13,NABP2,DUS2,ARHGEF2,ANP32A,ATG13,NDUFS8,STAT3,SLC35A1,MICAL3,MYO5A,AMPD2,B3GALT6,TXNL1,TGFB1,ELOVL5,COA3,PPP1R9B,DCAF6,HEMK1,FAM49B,TIMMDC1,ATP2C1,NADK2,RFFL,COG1,PRMT2,LEMD2,MTMR3,CTSL,UPF1,ELMO1,DTX4,ACAT1,CENPT,PLOD3,HRAS,RAB3IL1,CCDC93,TMED7,RAB14,FGFR1OP,ADD1,KDM4A,MRPS15,MAP3K7CL,PIGQ,AGPAT1,XIAP,GLUD1,CNTROB,PPP1R16B,MIEN1,ANKRD23,MIS12,PABPC4,CALM2,CDK5,PSMD1,CIPC,NEK6,GSDMB,RABGAP1L,PDS5B,NUP153,KCNAB2,PCBP2,MLST8,PGAP2,PLK3,TMEM115,AATF,MRPL43,HSDL1,MCL1,TOPORS,PPFIA3,SMC2,ICMT,SLC50A1,PLEKHF2,STOML2,TRIM47,WDR11,AXIN1,LIMK1,PRDX5,VIPAS39,MLYCD,ST3GAL2,ATP6V0C,SMG9,FBXL3,TFDP2,LONP2,AAAS,PFKP,DDX42,NDUFV2,MRPL9,MRPS2,TOP2B,TMED3,ITGB5,LMNA,MCTS1,DDRGK1,GNS,EIF2S2,MCM5,RTCB,CARS2,NAGPA,CYFIP1,TIMM8B,RB1CC1,PRRC2A,DHX29,PGS1,MAN1B1,RPS10,SRSF5,MPG,ABCF1,RHOB,CYB5A,NCDN,SCARB2,OSBPL11,DUSP3,CSK,MDH1,CNOT6,NDE1,HEXA,SNX14,RNF139,EGLN1,ANKRD27,FAM208B,ABCA3,SARNP,TRERF1,IVNS1ABP,UBR2,CHD1L,ACTR3,MON1B,TMEM97,RMI2,WDTC1,MYH9,NUF2,RXYLT1,NIT2,NIPA2,PRKACA,STAM,KTN1,APP,PRKD3,RAB21,ATP2A2,GRSF1,DUT,NUP107,ANKRD13C,ANAPC7,RNF19A,CEP63,MAVS,ATF2,CLN6,GCC1,TMEM9,DCTN1,ATP6V1G1,ADCY7,ENPP4,SHOC2,PSRC1,RNPS1,ATP6V0A1,CDCA2,NDUFA7,DNAJA1,TAZ,DDX17,CHCHD3,PEX5,CDC16,SEC61A1,NT5C3B,WDR7,RPLP1,RBMS1,MBOAT1,TICAM1,PDXK,FUS,GALK1,RPS2,TMBIM4,ANXA6,TRAK1,JMJD6,SIKE1,AKT1S1,WRB,PNO1,FBXO3,CAPN2,ERH,ADD3,GATC,NDUFB4,DCP1A,GTSE1,GEMIN6,TPCN1,S100A6,TMX1,LYPLA2,IMPA2,MFSD12,LDHB,NUDC,PDPK1,MOB4,PPP3CA,TK1,GUK1,TNFAIP3,GALC,JTB,MRPS10,MTMR12,PDE3B,CIP2A,KIF18A,KEAP1,CCDC6,TATDN2,WNT5B,MAPK6,LRPPRC,PML,SLC25A19,HMGB2,RGL1,PSAP,IGBP1,ANAPC4,FAF1,SNAPIN,SRM,COX15,AGRN,THOC1,GNPDA1,PPP1R15B,MCCC1,CSNK2A1,CDIPT,SEC16A,BIRC2,GIT2,KCMF1,ATPAF1,SSR1,ABL2,ETV6,TRMU,PIK3R2,PPCDC,TXLNA,ZFYVE27,MCMBP,MRPL32,CCAR1,CDC37,METTL1,EXOSC6,PBXIP1,HARS,BAZ2A,MRPL12,CYSTM1,EZR,LRP5,BRCA1,ESYT1,PRKRA,ANLN,STX16,RAB5B,RHEB,OPTN,DPYSL3,EPB41,SEPT1,TBC1D17,CDCA4,TIMM13,NAGLU,QRSL1,ACTB,PIEZO1,DHFR2,OSGEPL1,NUDT11,NAA60,C2CD5,GEMIN7,SEPHS2,LZTR1,TMUB1,ASAH1,RACGAP1,PPP3CB,B4GALT4,DOCK11,CRLF3,RAPGEF6,SNRNP25,VASP,NUS1,TIGAR,VMP1,PPIL2,SLC27A4,ALDH18A1,TMEM8A,PREB,ABCC1,CYTH1,TRAPPC9,AACS,NQO2,MEMO1,UTP15,KRAS,ARPC1A,EIF4G2,ZDHHC3,ZNF174,SPATA33,PSMC4,MOSPD3,GOLGA4,SYNCRIP,CDC27,SNAP23,PRMT7,ATP5F1A,NIPA1,RNF114,KCTD7,NDUFA5,CYLD,UGP2,MRPL39,DYNLL1,COPE,ZADH2,GGPS1,DUSP22,COMMD8,RPL11,RAD23A,SEC11A,CSDE1,PDK2,ATP6V0B,ZBTB21,MDM2,DUS4L,MRPL34,CORO1A,MINPP1,GM2A,POC5,DVL2,RPL29,TIMP2,RPL35,PSMA8,COQ10B,BTG2,CPOX,TUBGCP5,SLC26A6,FRAT2,DNAJC9,MTMR6,NFATC2,PRPF3,TXNL4A,RPSA,MRPL2,DNAJC10,ATP1A1,CLK3,SCAP,PSMD3,TOMM6,TIMM17A,NDUFA11,CEP55,ZNF436,NCOA1,LTA4H,AP2S1,SLC25A39,ZNF146,SMAP1,GOLIM4,MIF4GD,CDT1,GNE,ARFIP2,SUMF1,CHAC2,GGA2,CSNK1A1,AP3S1,TFRC,WRNIP1,PTPN2,IRF4,STARD9,GSTK1,NDUFV1,SLC1A4,SLC35B4,SS18L1,ABCD1,DDX31,CENPM,PTGES3,CAMK2G,RPAP3,MLEC,CNTN5,SNX2,BORA,RHOT2,CHCHD6,NEU1,KPNA4,FBXO41,GOLGA7,BIRC5,TFE3,SNAP29,CDCA7L,PGRMC1,GLG1,FAM126A,PKD2,SPCS3,ACADM,RPS6KC1,UBE2C,CHMP7,GCSH,PPCS,NDUFB6,ZDHHC8,TMEM109,TAP1,YTHDF3,NHLRC3,CCNB1,IKBIP,POLR3K,RIC1,C14orf119,KIFC1,SNUPN,ASAP2,DBNDD1,CYB5RL,CDC25B,TFG,SPTSSA,SEH1L,USO1,ATG9A,AKT2,ARHGAP45,DDX20,GALNT7,SLC17A5,AMDHD2,AURKB,CCNF,MCFD2,SLC25A5,FOXRED1,STT3A,TMED10,PSMD8,WDR4,EIF2D,PTPN7,ITGB1,DHTKD1,SARAF,UQCRH,RRS1,ARRB2,TRAF5,RTN3,SVIP,DDX58,WSB2,PPIB,HSPH1,MAPRE1,MUT,GMFG,CHTF18,HLA-E,ADO,KIF23,NDUFA4,MAN2B1,SLC35B1,PMF1,NOTCH2,COPG2,CFLAR,NDUFS4,NDUFAF6,FKBP1A,SLC31A1,RNF121,MEX3C,SNX18,HDAC7,ATIC,DAD1,BDH1,CTPS1,SLC25A51,ATP6V0A2,PCYT2,RNF135,PIKFYVE,GNAI2,LPCAT1,EEF1D,TMED2,FTL,DDX28,SIGMAR1,NOA1,PIP4K2C,SEPT8,DCTD,PLEC,PKM,CYFIP2,TOMM40,PATL1,PSMB3,FAS,ADSS,EPRS,SERTAD2,SERF2,NSF,CSNK1G1,QARS,DCK,ERGIC3,ACLY,LPCAT4,PPP3R1,VCPIP1,TCOF1,PPP6R3,MAP3K5,PPP6R2,RNF14,CDK2,NRBP1,CABLES1,ZC3HAV1,SYS1,TRIP10,RPS6KA1,CAST,EIF3D,GPR89A,RAC1,OLA1,ADPGK,SLC25A44,SNN,AP1B1,SDHA,GNB2,MOAP1,TERF2IP,CRKL,FLAD1,CYHR1,APLP2,SHC1,UCHL5,CDKN1B,TALDO1,NAA35,TMBIM1,MRM2,GPX4,CCT2,ATP13A1,MKLN1,ERF,TAOK1,LYRM1,CUL3,SLBP,CDC23,POLG2,PSMB9,AP4E1,DHX57,CENPU,SOCS7,HSPA4,JAK1,PPP2R5A,MRPL55,FAAP100,GOLGA8A,GUCY1B1,STAT1,SEL1L,PPA2,TRIM32,B4GALT3,PDCD11,CSNK1D,OTUD5,ANKRD13D,PKP4,TWNK,MRI1,BABAM1,CDCA3,SLC25A12,BRAP,AGPAT3,SDF2L1,BLM,SPR,RAB11A,REEP5,FOXO3,MAD2L2,PIP5K1C,MAT2B,RPL17,PTEN,CENPJ,CRAT,AHSA1,PRC1,UPF2,SLC38A10,COPS7B,TAGLN2,CNOT6L,OSTC,CREB1,MAP3K14,CNPY3,UBE2M,PACS2,SMC4,STRIP1,DENND1B,DENND4C,NET1,PARP4,ILF3,RPL8,TBRG4,ANAPC2,LRRC1,RHOT1,RPL27A,MARK2,ECH1,PRDX1,YIF1A,FBXO21,NUCB1,PLD3,SGSH,HGS,ATP5MC3,PFDN4,TTLL4,PRDX3,CCZ1B,STX18,TFDP1,NAXE,KHSRP,ASNA1,BYSL,VPS29,ESYT2,S100PBP,MIB2,ADA2,NPHP4,ST13,NF1,ALKBH5,MOGS,UBE2Z,KIF2C,SIRT2,AGFG1,SNRPD3,UBQLN2,USP48,FKBP2,MAPK14,BECN1,CUTC,RNF103,EDC3,BCAT2,RAP1A,THADA,EIF4A3,AP3S2,ATG3,IMPAD1,DPYSL2,PHTF1,SRI,AKR1B1,KIF22,NDUFB9,JOSD1,RP2,NFU1,TECR,OGG1,ARID4A,TRIM14,FGFR1OP2,TIMM50,COPS8,TRIM8,DPM1,FOPNL,RRM2,SLC25A22,SOX4,STK17B,ABHD5,GEMIN5,CXXC4,TIMM29,ATXN2L,PQBP1,IARS2,GALNT10,ROCK1,COPS6,SASS6,RPS26,PSMC1,STARD3NL,TBC1D12,RPS15,PIGN,AGTRAP,TM9SF4,CDIP1,CIB1,TIA1,MEF2A,EPHX2,RHBDD1,APOPT1,NFATC3,BANF1,CAPZA1,KIFAP3,BCL2,GLTP,YBX1,KNTC1,ACAD8,N4BP2,ALDH9A1,KDELR1,VOPP1,TSTA3,OXR1,PSMA1,SEPT7,ISG15,CAND1,GNAS,TSC1,NAP1L1,NSMF,CDCA5,ODF2,EXOC4,TRMT10B,PITPNA,RBBP4,NANP,NAA20,NIPSNAP2,HNRNPDL,PTDSS1,MZT2B,PDSS2,WASF2,TMEM106C,MMACHC,TOMM20,ASH1L,IMMT,FAM92A,IFI27L1,MPHOSPH8,GNPNAT1,CHERP,WDYHV1,CHKB,IRF3,TWF2,PAIP1,MIEF1,ANKRD28,FARSA,BABAM2,CCDC50,SAR1A,AKAP8,PARL,RPN2,APOOL,CHTOP,F2R,PDIA6,ABI1,TMEM14C,SCYL3,HTRA2,RLIM,MOSPD1,ACSL5,FAM172A,CGAS,ZNF500,DMAC2,PSMB7,NLN,WIPF1,BOLA1,TOR1AIP2,NDUFB1,PEF1,GFER,EIF3G,BTBD1,DAP3,TAB2,TULP3,CHCHD1,WDR59,CANT1,SCARB1,GAS2,USP11,AKNA,SMURF1,REEP4,PPP2R2D,MIF,KIF3B,CDS2,GOLPH3L,MRPL42,CASP6,TOR3A,SRGN,MRPS26,LETMD1,TIMM21,MFSD10,RGS1,MAN1A1,FBXO5,GART,TANK,BRD7,YIF1B,TTC17,MRPL11,SLC25A1,SAMD4B,ZDHHC18,CSNK1G2,TELO2,ADAM17,PRKAR1B,POLR3GL,WDR81,MEN1,ATP5MF,SYMPK,TARS,MAPK3,MFN2,HSPA1B,CNOT9,HLA-B,OSBPL8,COX8A,KBTBD7,ATP6V1C1,IDH3B,PREPL |
| 1.406e-60 | -137.81 | metabolic process | biological process | GO:0008152 | 9741 | 1857 | 17256 | 2622 |
ZBTB10,HEXB,TGOLN2,LACTB2,CCNL2,RBM4,ZNF275,FBXO22,EEF2K,RPL23A,USF1,RAD23B,MECR,DNM2,UPRT,CRY2,ECD,RNF26,ZNRD1,TIPARP,ANKRD9,MGAT5,RHBDD2,FTSJ3,MRPL57,USP34,BAK1,ERCC1,ZNF559,NRAS,GABPA,EHMT1,HNRNPF,WDHD1,MIER2,DIDO1,MCM2,ARF4,GINS4,MID1IP1,SMAD2,RAD18,RPS27A,MYO18A,OGT,COX5A,RNASEL,KLHL42,SMAD1,CHPF2,ZNF75A,OAZ1,SMNDC1,SLC25A33,ZNF720,HIVEP3,CLSPN,GGA1,MUM1,TRIO,DHX9,RAB23,KCTD17,EIF2AK4,PDCD7,PSMD9,APH1B,PARN,CDC73,ATG4A,TFAP4,PDXP,SMC3,RNFT1,FBXO7,EFTUD2,GEMIN4,MRPL21,CPSF4,NUP85,PABPC1,PHKG2,NSUN4,PPA1,LUC7L2,SRSF11,EIF3L,AGGF1,FOXK1,MAPKAPK3,MTA2,MTFR2,SF3B6,ERO1A,TYW1,GTPBP4,USP10,BCLAF1,MRPL16,ELK1,EIF4H,RDH11,FNTA,KPNA1,ETS2,TYW5,WIPI2,ZNF830,CFAP20,ACSF2,NUP58,MRPL3,ALS2,TRIM41,KARS,NQO1,PTTG1,VTI1A,STARD7,INO80E,SLC35B2,GLRX3,RCOR3,LCLAT1,CPNE3,ABHD16A,RBM23,FBXL6,ZNF420,MTA1,UBA5,GMEB1,NABP1,NSFL1C,INTS12,ZNF226,GPD1L,ZC3H3,RPRD1B,CGGBP1,PDCL3,CPNE1,ULK3,SEC61B,ERMP1,POLR2L,EID1,KAT7,IDH3A,CRNKL1,RPL38,E2F3,POLR2D,HTATIP2,PFKFB3,MEF2D,RAB1A,MAT2A,PPP2CA,ALDH3B1,LSM6,NSMCE2,CAMKMT,RNF38,DMWD,SNRPG,PPP5C,PITRM1,USP13,COMMD10,ZNF445,SRSF6,ZFP91,TRMT6,CCM2,HABP4,ABHD14B,ATG2B,IP6K2,ATP5F1B,WDR5,PMVK,NEXMIF,RRP36,NEIL2,TUT4,SRXN1,PPP1R3B,GOLM1,RPA2,ZBTB45,PSMD2,CLIC4,ITGB8,COQ4,HUWE1,ZNF260,NAA50,LTN1,KANSL2,UBE3B,ST8SIA2,ZNF710,GTF2H2,FBXL19,RPL22L1,MED22,SPTAN1,DDX24,USP42,MRS2,LDHA,PICALM,UTP20,SLC19A1,MAGT1,GPS2,ACOX1,PARG,DBI,AEN,CD81,PARP10,YWHAH,WDR45B,THAP5,TRIM11,YTHDC2,RBM8A,SND1,RUFY1,FANCI,PAPOLA,ZER1,KRR1,CREM,TET3,FANCL,RAB8A,NUP210,GLIS2,NT5DC1,IL6ST,INTS1,SLC44A1,POP7,NOC2L,EIF5,MTPN,ASB6,RYBP,PLK1,RPP25,PTPN18,RBX1,APH1A,RAD51AP1,SNRPB,CDC6,UBE2V1,PBRM1,EAF2,UTP3,KRTCAP2,ODC1,LUC7L,USP21,ALG3,TRIM4,TRAM2,AGPAT2,CHD3,ZNF367,E2F4,ARRDC1,ADAM9,PRPF4,KPNA2,DVL1,CLN3,BEND6,FAM208A,NGLY1,POT1,ZNF564,FUBP1,RMND5A,CTU2,ZCCHC9,PHB2,CENPF,SDC2,LAMTOR3,CHCHD2,COX4I1,ADCK5,CDK13,RAB6A,CNOT11,RSAD1,ARID1B,C1GALT1,SUB1,MLX,UBE2Q2,CCP110,MBD2,SSBP3,XPA,ZNF746,CTR9,AHCY,ICE2,RBM3,GLE1,MRPL48,LRSAM1,HDHD2,NTPCR,ABHD2,DCAF8,NSDHL,ACSL3,LDB1,AMD1,MAP4K3,ZNF761,METTL22,ARMC8,STYXL1,RBM38,NMT2,IRF5,RMC1,RPL36,RXRB,SDHB,PAXX,MBIP,GALNT2,ORMDL2,COX7A2L,ZDHHC7,DTD1,RUVBL2,ECPAS,BCCIP,USP7,SART1,GLT8D1,TRAF7,RPLP2,SUCLG1,ARID2,NDUFAF2,TMX4,SLC2A1,LAGE3,ZNF416,ZFYVE21,RRAGC,ATP6V1B2,LYN,PCBP1,ZNF121,MRPL50,VAV1,NRF1,PSMA6,ZNF473,KMT5C,BRPF3,ZNF302,ABRAXAS2,PIN1,PPME1,RPAP1,TARDBP,LMAN1,TOP1MT,AHCYL1,STRAP,SPIDR,CTDSP2,SPSB3,ZNF583,PRPF19,SNX25,PPIF,KDM3B,MND1,BIRC3,POLR2G,ZNF780B,PPT1,RAB7A,PPIE,NUP155,DCLRE1C,CHMP2B,VDAC1,MRPS14,RHBDF2,EIF3H,SUGP1,IDE,DHX16,RBL1,UBXN2B,FASTK,STK38,UHRF2,CHMP4B,XRCC3,H3F3A,CHID1,SMAD4,RAD51D,SLC30A9,NADSYN1,NIFK,CMAS,MCM10,MTERF1,KLHL21,AGO2,TMX3,CDCA8,GTF3A,ARF1,CDK11B,PAGR1,SCYL2,DNAJB9,HERC3,GTPBP3,CTSS,POLR1B,ORC3,RNLS,RNF5,RBM15B,YTHDC1,ACP2,RHOA,RPRD1A,HMGN5,PRKDC,METTL5,TUFM,TOP3A,RANGAP1,PNPLA8,PCGF1,HAGH,DDX23,PDCD6,NEK1,L3MBTL3,NEIL3,CTBS,BBX,E2F1,IMPDH1,USP20,RBPJ,TAF12,NR2F2,PGAM1,HIPK3,IFI16,TXN,NUP188,MAX,PDCD6IP,GXYLT1,ADAM10,PRKCSH,CXXC1,CUL1,USP39,NANS,GYG1,UBE2I,OAT,MYEF2,PARK7,ASPHD2,PA2G4,MTFR1L,NOL11,FIZ1,RAB4A,ZNF200,TRA2B,FBXW2,SUCLG2,AP2B1,CISD2,TAF5L,SLC26A2,MARCH2,ZNF800,CDC5L,SRSF10,ZNF524,KLF10,NSUN2,LACTB,SUPT20H,USP22,CBFB,RFC2,CLNS1A,EIF3A,PRIM1,DOT1L,IWS1,MAP3K4,HHEX,MKNK1,BRD2,RPS14,TPP2,LUC7L3,MRPL27,BTF3,PTPDC1,SLF1,CCDC59,B4GALT2,PTOV1,PRPF38B,RECQL,COX5B,EWSR1,DHPS,POLR2K,GSPT2,PRKAA1,RRM1,TATDN3,B4GALT1,CYCS,SUPT7L,PRPF39,ZNF79,ZNF518A,PSEN1,TMEM165,PDXDC1,VPS25,NDUFS7,YY1AP1,NPLOC4,CNOT3,WDR48,RPN1,LHX8,EXOSC7,KLHL5,ZNRF2,PPP4R1,MSH2,DAPK1,TPST1,PIGG,FBXL7,MRPL40,CYC1,MRM3,APOL1,FDFT1,SOCS5,EIF5A,PRIM2,PIGT,CPQ,ELL2,COQ8A,RDH10,MFNG,USF3,ZNF574,RPS24,EXOSC9,ARID1A,ADRB2,MTR,MAP2K2,PHF6,TWISTNB,PI4K2A,XRCC5,DERL1,CAT,MTHFD2,GOLGA2,EPOP,RBMX,MED15,PIAS2,USP32,CEBPG,SAMD8,SMPD4,GPI,NUDT3,ZNF511,NDC1,ATXN3,TP53RK,RAB11B,RAF1,UROD,C2orf49,CD320,SPINDOC,NUDT19,DECR1,CCNA2,SIAH1,MTMR4,ADCY9,LPIN2,SOCS6,MRPS27,TTC3,RNASEH2A,AQR,CDK12,ILKAP,CFL1,SAP30,BRD4,DRAP1,NARF,ELP4,EDF1,PKMYT1,ASB13,ERC1,SERP1,TRIM28,SUPT16H,AMZ2,EIF3K,ANKZF1,ZNF282,RAD51C,CHMP4A,HINT1,DDOST,RAB24,DGCR8,CERS6,SAFB,FTSJ1,ATF6,BEND3,XRCC4,EYA2,ADAM23,PRPF4B,NDUFS1,DEPDC1,B4GALT5,MANBA,MECP2,TKT,CBLL1,ARGLU1,SECISBP2,POFUT1,HMG20A,WWP2,EBP,RFWD3,CCNK,DNAJC8,NDUFA2,ELP5,FUT8,PTPN11,AXIN2,MRPL54,FEM1B,RPL19,CARF,CITED2,NDUFA3,MSH6,KAT2A,LONRF3,RFXANK,ADSL,FBXO9,BMS1,KCNQ1,OTUD3,ARSK,GUF1,KLF6,COMMD4,SPPL2B,FADD,SH3GLB1,CBX3,RPL32,ZHX1,OAZ2,PPP1R11,DUSP11,DDX5,NDUFS5,WDR62,WDR91,TAF6,ESPL1,PURA,DDB1,HIGD2A,RORB,CCNC,POLA2,ZNF76,PIGM,LYRM4,KMT2E,UQCR10,PHRF1,HMGXB3,PTP4A3,UBE2Q1,COMMD5,MAP1LC3B,ATP5PF,MRPL19,ZNF696,SF3B2,PCYOX1L,CDC42,GOT2,RAB35,JAZF1,HADHB,RPF2,GPATCH1,TCEA1,SLC35C2,CARMIL1,DRAM2,CARM1,SRPK2,WDR41,DEAF1,LARS,SNRNP200,NCK1,LAP3,VHL,RIOX2,SREK1,SUMF2,PITPNB,KMT2C,PRPSAP1,MPC1,ASF1B,RPL37,MAN2A2,BRWD1,U2SURP,PPM1G,CRCP,CAB39,BAZ1B,STK11,ZNF268,CHEK2,CLU,VPS4A,CHPT1,MRPL13,DCAF5,CAPN1,UBE2D3,NSMCE4A,PPP1R2,PPP1R12A,ZCCHC8,GORASP1,NACA,UBXN1,PCSK7,RPL15,PM20D2,THRAP3,XPNPEP3,QSOX2,TTF1,PRPF18,NUP205,CHKA,LYAR,DTL,MED10,PYURF,EI24,TENM3,ZRANB1,CSNK1G3,ATP5IF1,POLR2I,ERLIN1,NUDT4,SUGP2,RPL6,GBA,SYVN1,EIF2A,VKORC1,CCDC71L,SLTM,DAPK3,MASTL,UAP1,KLHL15,NFIL3,SIAH2,SLC16A1,FN3KRP,CTSA,DNPH1,SNRNP70,APOL2,TSEN15,ADNP2,TCF12,PRKAB1,CHMP2A,MDH2,PMS2,UCK2,SMARCA4,UCK1,ORC1,EXT2,MXD1,USP5,HNRNPA2B1,SAP130,RRN3,UBXN2A,IARS,CD3EAP,KIF14,EXOSC1,PPP6C,CS,CYB5R1,UTP4,ZNF770,CSTF1,CHP1,POU2AF1,UBQLN4,NXT1,HPDL,PGGT1B,RNF25,METTL2A,SMU1,PCGF6,LSM8,ATXN1,GLO1,OGDH,EDEM2,TOLLIP,FANCE,MBD3,RPS9,PDHX,ALKBH6,PON2,DUS3L,HNRNPR,STAT6,ARNTL,FKBP5,BRD9,MAPK1,ABCA1,CWC25,PDF,NAT14,DNAJC2,GCLM,TRIP12,ZNF316,SHPRH,RAE1,SCYL1,NUP54,PAWR,MXD4,DCUN1D4,PIP4K2A,GFM2,SPPL2A,FASTKD3,FGFR3,GRK2,KLHL20,KMT5A,PPIG,RRBP1,NABP2,DUS2,ANP32A,ATG13,NDUFS8,FBL,ERI3,STAT3,SLC35A1,MICAL3,MYO5A,AMPD2,B3GALT6,TXNL1,TGFB1,ELOVL5,PPP1R9B,DCAF6,HEMK1,HELB,PSPC1,MIER1,NADK2,RFFL,RCOR1,PRMT2,CDK11A,TFEB,MTMR3,CTSL,UPF1,ZC3H7B,DTX4,KMT2B,ACAT1,ZMIZ1,PLOD3,HRAS,TERF1,SLF2,RAB14,FGFR1OP,ADD1,KDM4A,MRPS15,MAP3K7CL,PIGQ,AGPAT1,XIAP,DHX8,GLUD1,EDRF1,PABPC4,CDK5,PSMD1,CIPC,NEK6,NSRP1,SRSF4,PDS5B,NUP153,FNIP2,SENP1,KCNAB2,PCBP2,PGAP2,PLK3,ZNF672,TMEM115,MRPL43,TOPORS,DCUN1D5,ICMT,PLEKHF2,STOML2,BRMS1,ZNF689,AXIN1,LIMK1,PRDX5,ATE1,VIPAS39,MLYCD,ST3GAL2,SMG9,FBXL3,TFDP2,E2F2,LONP2,AAAS,PFKP,DDX42,SSRP1,NDUFV2,MRPL9,MRPS2,PHF23,CERK,TOP2B,EZH1,ZNRF3,MCTS1,RAVER2,DDRGK1,GNS,DDX56,EIF2S2,INTS7,INPP5A,MCM5,RTCB,ZNF326,FOXN2,CARS2,UBE2QL1,NAGPA,ETV3,RB1CC1,DHX29,ZMYND11,PGS1,MAN1B1,TEX10,MYBL2,RPS10,ARMT1,SRSF5,CBFA2T2,MPG,ABCF1,CYB5A,PTPRF,SCARB2,POLR2J,DUSP3,CSK,SETD3,TEX30,PTAR1,MDH1,CNOT6,PLPP6,HEXA,SGF29,SNX14,RNF139,EGLN1,ZNF296,ABCA3,SARNP,TRERF1,IVNS1ABP,UBR2,CHD1L,RMI2,WDTC1,MYH9,CREBL2,RXYLT1,NIT2,ZNF267,EFL1,SAFB2,PRKACA,TCF19,STAM,KTN1,APP,ANKIB1,PRKD3,SP100,ZKSCAN1,UTP18,GRSF1,DUT,DDA1,NUP107,ANAPC7,RNF19A,MAVS,ATF2,RBM15,CLN6,RNF169,ADCY7,ENPP4,INTS13,MAP4K4,RNPS1,WBP2,ATP6V0A1,NDUFA7,TAZ,FKBP3,DDX17,TAF2,CHCHD3,PEX5,CDC16,HIPK2,NT5C3B,RPLP1,RBMS1,MBOAT1,PDXK,FUS,GEN1,ZBTB11,LRP8,GALK1,ZNF786,RPS2,TRAK1,JMJD6,UBE4A,ETS1,PLPP5,PNO1,ZNF92,KRI1,FBXO3,CAPN2,ERH,SUV39H2,GATC,NDUFB4,PPP1R8,PRDM4,DCP1A,GTSE1,GEMIN6,TTLL12,TMX1,HNRNPM,LYPLA2,IMPA2,LDHB,PDPK1,PPP3CA,TK1,GUK1,TNFAIP3,GALC,POLK,ZNF512,MRPS10,MTMR12,DDX39A,PDE3B,RPA1,ZNF862,ZNF180,KEAP1,POLE,TATDN2,PITX1,MAPK6,CAPN7,LRPPRC,PML,SLC25A19,HMGB2,PSAP,USF2,ANAPC4,FAF1,SNAPIN,SRM,COX15,DDX47,AGRN,THOC1,GPBP1L1,GNPDA1,PPP1R15B,MCCC1,CSNK2A1,EBNA1BP2,CDIPT,BIRC2,LIN9,ABL2,PCNA,ZNF639,ETV6,TRMU,PIK3R2,XRCC2,PPCDC,FAM86C1,MCMBP,MYBL1,MRPL32,CCAR1,ABCC5,PTPRK,CDC37,METTL1,SP3,EXOSC6,HARS,BAZ2A,TLK1,MRPL12,GMFB,EZR,LRP5,BRCA1,ESYT1,PRKRA,OPTN,TBC1D17,TONSL,NAGLU,SOCS4,QRSL1,ACTB,DHFR2,OSGEPL1,ZNF45,NUDT11,NAA60,GEMIN7,SEPHS2,TMUB1,CTCF,ASAH1,PPP3CB,B4GALT4,RLF,ASXL2,SNRNP25,RB1,NUS1,MED8,TIGAR,VMP1,CMTR2,PPIL2,SLC27A4,TIMELESS,MDFIC,MAML1,ALDH18A1,PREB,ABCC1,AACS,NQO2,UTP15,KRAS,EIF2AK1,RTF1,UBE4B,NFATC2IP,LY6E,EIF4G2,ZDHHC3,ZNF174,PSMC4,SYNCRIP,PALB2,CDC27,PRPS2,TBPL1,PRMT7,ATP5F1A,RNF114,KCTD7,NDUFA5,CYLD,UGP2,FOXM1,MRPL39,DYNLL1,XAB2,SUMO2,ZADH2,GGPS1,DUSP22,RPAIN,COMMD8,RPL11,RAD23A,SEC11A,CSDE1,PDK2,ZBTB21,MDM2,DUS4L,MRPL34,MINPP1,SAP30L,GM2A,DVL2,RPL29,RPL35,PSMA8,COQ10B,BTG2,CPOX,CYP20A1,MTMR6,NFATC2,PRPF3,KDM1B,TXNL4A,USP36,RPSA,SRSF1,MRPL2,DNAJC10,ATP1A1,CLK3,ZNF700,SCAP,MAFK,PSMD3,TOMM6,NDUFA11,ZNF436,DNAJC17,NCOA1,LTA4H,AP2S1,SLC25A39,USP53,ZC3HC1,INTS2,CTDP1,CDC40,RRP15,DAP,CDT1,GNE,ARID5A,SMC6,NKRF,SUMF1,CHAC2,GGA2,CSNK1A1,RMI1,TFRC,WRNIP1,PTPN2,IRF4,GSTK1,NDUFV1,CWC27,SS18L1,ABCD1,DDX31,PTGES3,CAMK2G,MLEC,CNTN5,ZNF202,ZMYM5,PPWD1,NEU1,FBXO41,GOLGA7,BIRC5,TFE3,SNAP29,CDCA7L,FAM126A,SPCS3,ACADM,RPS6KC1,UBE2C,SAT2,GCSH,ZNF496,PPCS,NDUFB6,ZDHHC8,NHLRC3,CCNB1,EIF1B,COMMD6,SLC20A1,POLR3K,UTP25,SNUPN,CYB5RL,PARPBP,RNASEK,CDC25B,MAST2,PLCL2,SPTSSA,DNMT1,SEH1L,ATG9A,AKT2,PBK,NOL8,ELOA,MRNIP,DDX20,GALNT7,AMDHD2,AURKB,CCNF,MCFD2,FOXRED1,MAK16,RBM47,STT3A,PSMD8,PTER,WDR4,EIF2D,PTPN7,ITGB1,DHTKD1,UQCRH,RRS1,ARRB2,ZNF598,HDAC2,DDX58,WSB2,PPIB,LIME1,MUT,GMFG,CHTF18,ADO,NDUFA4,MAN2B1,PMF1,NOTCH2,METTL3,JMY,CFLAR,NDUFS4,NDUFAF6,FKBP1A,RNF121,KLF16,HDAC7,ATIC,DAD1,BDH1,CTPS1,ATP6V0A2,PCYT2,RNF135,PIKFYVE,LPCAT1,EEF1D,TERF2,MORC3,PHF10,DDX28,ZNF84,NOA1,PIP4K2C,DCTD,PKM,CYFIP2,TOMM40,KDM3A,PATL1,SF3A2,PSMB3,ADSS,EPRS,ZNF777,SERTAD2,ZFP92,CSNK1G1,QARS,DCK,ACLY,DCAF11,LPCAT4,PPP3R1,VCPIP1,YY1,MAP3K5,RNF14,CDK2,NRBP1,ZC3HAV1,DNMT3A,RWDD1,ZBTB37,RPS6KA1,SF3B1,SUZ12,EIF3D,RAC1,OLA1,KLHL18,ADPGK,SDHA,SDE2,TERF2IP,CRKL,FLAD1,APLP2,ZNF75D,SHC1,KDM2A,UCHL5,TALDO1,NAA35,MRM2,GPX4,RFC3,ERF,TAOK1,CUL3,SLBP,KIAA1586,GALK2,CDC23,POLG2,PSMB9,GAR1,DHX57,CENPU,PRDM11,SOCS7,NSA2,VEZF1,JAK1,PPP2R5A,MRPL55,ACYP1,TBL3,FAAP100,GUCY1B1,H2AFX,STAT1,SEL1L,PPA2,TRIM32,B4GALT3,PDCD11,CSNK1D,ATMIN,POLQ,POU3F2,OTUD5,NCOR2,TWNK,TCF3,MRI1,BABAM1,CDCA3,SLC25A12,BRAP,AGPAT3,MYNN,SDF2L1,BLM,SPR,RAB11A,FOXO3,MAD2L2,PIP5K1C,GTF2F1,RBM17,MAT2B,RPL17,PTEN,CRAT,UPF2,COPS7B,CNOT6L,OSTC,CREB1,MAP3K14,UBE2M,PACS2,NCOA2,TSHZ1,ZFP64,RNASEH2C,NEK7,TRIR,WDR18,PARP4,ILF3,RPL8,TBRG4,ANAPC2,RHOT1,RPL27A,MARK2,TSR2,ECH1,PRDX1,POLR2A,FBXO21,NUCB1,PLD3,SGSH,HGS,ATP5MC3,TTLL4,PRDX3,HNRNPH3,TFDP1,NAXE,KHSRP,CPEB2,BYSL,ESYT2,DDX52,MIB2,ADA2,PTMS,IER2,UBE2E2,NOP2,DCAF15,NF1,ALKBH5,MOGS,DNAJC24,ZNF107,UBE2Z,SLC29A1,TAF6L,SIRT2,AGFG1,SNRPD3,UBQLN2,USP48,FKBP2,MAPK14,BECN1,SNAPC4,RNF103,EDC3,BCAT2,UBLCP1,MBD4,CYREN,THADA,EIF4A3,METTL14,ATG3,IMPAD1,DPYSL2,PHTF1,SRI,AKR1B1,KHDC4,KIF22,NDUFB9,ZBTB22,JOSD1,NFU1,TECR,OGG1,ARID4A,FGFR1OP2,TIMM50,ELOF1,COPS8,FYTTD1,TDP1,TRIM8,DPM1,RRM2,WDR82,SOX4,STK17B,DHX15,CHAF1A,ABHD5,PAF1,GEMIN5,UBTF,UEVLD,PQBP1,IARS2,GALNT10,ROCK1,COPS6,RPS26,PSMC1,STARD3NL,RPS15,PIGN,ZNF768,UFC1,CIB1,MED13L,MEF2A,EPHX2,SRRT,RHBDD1,NFATC3,ZNF449,BUD31,ZNF335,BCL2,GLTP,YBX1,ACAD8,UBE3C,N4BP2,ZNF189,ALDH9A1,VOPP1,TSTA3,CIC,OXR1,PSMA1,ISG15,CAND1,GNAS,NAP1L1,RBM25,CDCA5,TRMT10B,NUP62,ZFP90,PITPNA,RBBP4,NANP,NAA20,NIPSNAP2,HNRNPDL,PTDSS1,PDSS2,ZBTB24,MBD1,MMACHC,TOMM20,ASH1L,MPHOSPH8,GNPNAT1,CHERP,WDYHV1,PLAGL2,NSD3,CHKB,IRF3,CHD1,MEAF6,PAIP1,FARSA,ANKLE1,BABAM2,AKAP8,PARL,RPN2,CHTOP,PDIA6,ABI1,TMEM14C,SCYL3,HTRA2,RLIM,ACSL5,CGAS,ZNF500,PSMB7,NLN,NDUFB1,BUD13,PEF1,GFER,EIF3G,BTBD1,RAD54B,DAP3,ZNF317,TAB2,CHCHD1,CANT1,SCARB1,USP11,AKNA,SMURF1,TSPAN5,PPP2R2D,CBX4,MIF,CDS2,SH2D3A,MRPL42,CASP6,EYA1,SRGN,MRPS26,DBF4,KLF13,HDDC2,MAN1A1,GART,CTNNBL1,PELO,TANK,BRD7,MRPL11,SLC25A1,SAMD4B,GINS1,ZDHHC18,CSNK1G2,TELO2,GTF3C6,ADAM17,HMGN1,NASP,PRKAR1B,POLR3GL,WDR81,MEN1,ATP5MF,ZNF407,SYMPK,SNRPA,TARS,MAPK3,MFN2,HSPA1B,CNOT9,ATAD2,PLAA,OSBPL8,COX8A,KBTBD7,ZRANB2,SRSF3,MBD6,TATDN1,IDH3B,PREPL,TYW1B |
| 3.082e-60 | -137.03 | organic substance metabolic process | biological process | GO:0071704 | 9289 | 1791 | 17256 | 2622 |
ZBTB10,HEXB,TGOLN2,LACTB2,CCNL2,RBM4,ZNF275,FBXO22,EEF2K,RPL23A,USF1,RAD23B,MECR,DNM2,UPRT,CRY2,ECD,RNF26,ZNRD1,TIPARP,ANKRD9,MGAT5,RHBDD2,FTSJ3,MRPL57,USP34,BAK1,ERCC1,ZNF559,NRAS,GABPA,EHMT1,HNRNPF,WDHD1,MIER2,DIDO1,MCM2,ARF4,GINS4,MID1IP1,SMAD2,RAD18,RPS27A,MYO18A,OGT,COX5A,RNASEL,KLHL42,SMAD1,CHPF2,ZNF75A,OAZ1,SMNDC1,SLC25A33,ZNF720,HIVEP3,CLSPN,GGA1,MUM1,TRIO,DHX9,RAB23,KCTD17,EIF2AK4,PDCD7,PSMD9,APH1B,PARN,CDC73,ATG4A,TFAP4,PDXP,SMC3,RNFT1,FBXO7,EFTUD2,GEMIN4,MRPL21,CPSF4,NUP85,PABPC1,PHKG2,NSUN4,PPA1,LUC7L2,SRSF11,EIF3L,AGGF1,FOXK1,MAPKAPK3,MTA2,SF3B6,ERO1A,TYW1,GTPBP4,USP10,BCLAF1,MRPL16,ELK1,EIF4H,RDH11,FNTA,KPNA1,ETS2,TYW5,WIPI2,ZNF830,CFAP20,ACSF2,NUP58,MRPL3,ALS2,TRIM41,KARS,PTTG1,STARD7,SLC35B2,INO80E,GLRX3,RCOR3,LCLAT1,CPNE3,ABHD16A,RBM23,FBXL6,ZNF420,MTA1,UBA5,GMEB1,NABP1,NSFL1C,INTS12,ZNF226,GPD1L,ZC3H3,RPRD1B,CGGBP1,PDCL3,CPNE1,ULK3,SEC61B,ERMP1,POLR2L,EID1,KAT7,IDH3A,CRNKL1,RPL38,E2F3,POLR2D,PFKFB3,MEF2D,RAB1A,MAT2A,PPP2CA,ALDH3B1,LSM6,NSMCE2,CAMKMT,RNF38,DMWD,SNRPG,PPP5C,PITRM1,USP13,COMMD10,ZNF445,SRSF6,ZFP91,TRMT6,CCM2,HABP4,ABHD14B,IP6K2,ATP5F1B,WDR5,PMVK,NEXMIF,RRP36,NEIL2,TUT4,PPP1R3B,GOLM1,RPA2,ZBTB45,PSMD2,CLIC4,ITGB8,COQ4,HUWE1,ZNF260,NAA50,LTN1,KANSL2,UBE3B,ST8SIA2,ZNF710,GTF2H2,FBXL19,RPL22L1,MED22,SPTAN1,DDX24,USP42,MRS2,LDHA,PICALM,UTP20,SLC19A1,MAGT1,GPS2,ACOX1,PARG,DBI,AEN,CD81,PARP10,YWHAH,WDR45B,THAP5,TRIM11,YTHDC2,RBM8A,SND1,RUFY1,FANCI,PAPOLA,ZER1,KRR1,CREM,TET3,FANCL,RAB8A,NUP210,GLIS2,IL6ST,INTS1,SLC44A1,POP7,NOC2L,EIF5,MTPN,ASB6,RYBP,PLK1,RPP25,PTPN18,RBX1,APH1A,RAD51AP1,SNRPB,CDC6,UBE2V1,PBRM1,EAF2,UTP3,KRTCAP2,ODC1,LUC7L,USP21,ALG3,TRIM4,AGPAT2,CHD3,ZNF367,E2F4,ARRDC1,ADAM9,PRPF4,KPNA2,DVL1,CLN3,BEND6,FAM208A,NGLY1,POT1,ZNF564,FUBP1,RMND5A,CTU2,ZCCHC9,PHB2,CENPF,SDC2,LAMTOR3,CHCHD2,COX4I1,ADCK5,CDK13,RAB6A,CNOT11,RSAD1,ARID1B,C1GALT1,SUB1,MLX,UBE2Q2,CCP110,MBD2,SSBP3,XPA,ZNF746,CTR9,AHCY,ICE2,RBM3,GLE1,MRPL48,LRSAM1,ABHD2,DCAF8,NSDHL,ACSL3,LDB1,AMD1,MAP4K3,ZNF761,METTL22,ARMC8,STYXL1,RBM38,NMT2,IRF5,RPL36,RXRB,SDHB,PAXX,MBIP,GALNT2,ORMDL2,COX7A2L,ZDHHC7,DTD1,RUVBL2,ECPAS,BCCIP,USP7,SART1,GLT8D1,TRAF7,RPLP2,SUCLG1,ARID2,SLC2A1,LAGE3,ZNF416,ZFYVE21,RRAGC,ATP6V1B2,LYN,PCBP1,ZNF121,MRPL50,VAV1,NRF1,PSMA6,ZNF473,KMT5C,BRPF3,ZNF302,ABRAXAS2,PIN1,PPME1,RPAP1,TARDBP,LMAN1,TOP1MT,AHCYL1,STRAP,SPIDR,CTDSP2,SPSB3,ZNF583,PRPF19,SNX25,PPIF,KDM3B,MND1,BIRC3,POLR2G,ZNF780B,PPT1,RAB7A,PPIE,NUP155,DCLRE1C,MRPS14,RHBDF2,EIF3H,SUGP1,IDE,DHX16,RBL1,UBXN2B,FASTK,STK38,UHRF2,CHMP4B,XRCC3,H3F3A,CHID1,SMAD4,RAD51D,SLC30A9,NADSYN1,NIFK,CMAS,MCM10,MTERF1,KLHL21,AGO2,TMX3,CDCA8,GTF3A,ARF1,CDK11B,PAGR1,SCYL2,DNAJB9,HERC3,GTPBP3,CTSS,POLR1B,ORC3,RNLS,RNF5,RBM15B,YTHDC1,RHOA,RPRD1A,HMGN5,PRKDC,TUFM,TOP3A,RANGAP1,PNPLA8,PCGF1,HAGH,DDX23,PDCD6,NEK1,L3MBTL3,NEIL3,CTBS,BBX,E2F1,IMPDH1,USP20,RBPJ,TAF12,NR2F2,PGAM1,HIPK3,IFI16,TXN,NUP188,MAX,PDCD6IP,GXYLT1,ADAM10,PRKCSH,CXXC1,CUL1,USP39,NANS,GYG1,UBE2I,OAT,MYEF2,PARK7,ASPHD2,PA2G4,NOL11,FIZ1,RAB4A,ZNF200,TRA2B,FBXW2,SUCLG2,AP2B1,TAF5L,SLC26A2,MARCH2,ZNF800,CDC5L,SRSF10,ZNF524,KLF10,NSUN2,LACTB,USP22,CBFB,RFC2,CLNS1A,EIF3A,PRIM1,DOT1L,IWS1,MAP3K4,HHEX,MKNK1,BRD2,RPS14,TPP2,LUC7L3,MRPL27,BTF3,PTPDC1,SLF1,CCDC59,B4GALT2,PTOV1,PRPF38B,RECQL,COX5B,EWSR1,DHPS,POLR2K,GSPT2,PRKAA1,RRM1,TATDN3,B4GALT1,CYCS,SUPT7L,PRPF39,ZNF79,ZNF518A,PSEN1,TMEM165,PDXDC1,VPS25,NDUFS7,YY1AP1,NPLOC4,CNOT3,WDR48,RPN1,LHX8,EXOSC7,KLHL5,ZNRF2,PPP4R1,MSH2,DAPK1,TPST1,PIGG,FBXL7,MRPL40,CYC1,MRM3,APOL1,FDFT1,SOCS5,EIF5A,PIGT,PRIM2,CPQ,ELL2,COQ8A,RDH10,MFNG,USF3,ZNF574,RPS24,EXOSC9,ARID1A,ADRB2,MTR,MAP2K2,TWISTNB,PHF6,PI4K2A,XRCC5,DERL1,CAT,MTHFD2,GOLGA2,EPOP,RBMX,MED15,PIAS2,USP32,CEBPG,SAMD8,SMPD4,GPI,NUDT3,ZNF511,NDC1,ATXN3,TP53RK,RAB11B,RAF1,UROD,C2orf49,CD320,SPINDOC,NUDT19,DECR1,CCNA2,SIAH1,MTMR4,ADCY9,LPIN2,SOCS6,MRPS27,TTC3,RNASEH2A,AQR,ILKAP,CDK12,CFL1,SAP30,BRD4,DRAP1,ELP4,EDF1,PKMYT1,ASB13,ERC1,SERP1,TRIM28,SUPT16H,AMZ2,EIF3K,ANKZF1,ZNF282,RAD51C,HINT1,DDOST,DGCR8,CERS6,SAFB,FTSJ1,ATF6,BEND3,XRCC4,EYA2,ADAM23,PRPF4B,NDUFS1,DEPDC1,B4GALT5,MANBA,MECP2,TKT,CBLL1,ARGLU1,SECISBP2,POFUT1,HMG20A,WWP2,EBP,RFWD3,CCNK,DNAJC8,NDUFA2,ELP5,FUT8,PTPN11,AXIN2,MRPL54,FEM1B,RPL19,CARF,CITED2,NDUFA3,MSH6,KAT2A,LONRF3,RFXANK,ADSL,FBXO9,BMS1,KCNQ1,OTUD3,ARSK,GUF1,KLF6,COMMD4,SPPL2B,FADD,SH3GLB1,CBX3,RPL32,ZHX1,OAZ2,PPP1R11,DUSP11,DDX5,NDUFS5,WDR62,WDR91,TAF6,ESPL1,PURA,DDB1,RORB,CCNC,POLA2,ZNF76,PIGM,KMT2E,UQCR10,PHRF1,PTP4A3,UBE2Q1,COMMD5,ATP5PF,MRPL19,ZNF696,SF3B2,PCYOX1L,CDC42,GOT2,JAZF1,HADHB,RPF2,GPATCH1,TCEA1,SLC35C2,CARMIL1,CARM1,SRPK2,DEAF1,LARS,SNRNP200,NCK1,LAP3,VHL,RIOX2,SREK1,SUMF2,PITPNB,KMT2C,PRPSAP1,MPC1,ASF1B,RPL37,MAN2A2,BRWD1,U2SURP,PPM1G,CRCP,CAB39,BAZ1B,STK11,ZNF268,CHEK2,CLU,VPS4A,CHPT1,MRPL13,DCAF5,CAPN1,UBE2D3,NSMCE4A,PPP1R2,PPP1R12A,ZCCHC8,GORASP1,NACA,UBXN1,PCSK7,RPL15,PM20D2,THRAP3,XPNPEP3,TTF1,PRPF18,NUP205,CHKA,LYAR,DTL,MED10,PYURF,TENM3,ZRANB1,CSNK1G3,ATP5IF1,POLR2I,ERLIN1,NUDT4,SUGP2,RPL6,GBA,SYVN1,EIF2A,VKORC1,CCDC71L,SLTM,DAPK3,MASTL,UAP1,KLHL15,NFIL3,SIAH2,SLC16A1,FN3KRP,CTSA,DNPH1,SNRNP70,APOL2,TSEN15,ADNP2,TCF12,PRKAB1,MDH2,PMS2,UCK2,SMARCA4,UCK1,ORC1,EXT2,MXD1,USP5,HNRNPA2B1,SAP130,RRN3,UBXN2A,IARS,CD3EAP,KIF14,EXOSC1,PPP6C,CS,CYB5R1,UTP4,ZNF770,CSTF1,CHP1,POU2AF1,NXT1,HPDL,PGGT1B,RNF25,METTL2A,SMU1,PCGF6,LSM8,ATXN1,GLO1,OGDH,EDEM2,TOLLIP,FANCE,MBD3,RPS9,PDHX,PON2,DUS3L,HNRNPR,STAT6,ARNTL,FKBP5,BRD9,MAPK1,ABCA1,CWC25,PDF,NAT14,DNAJC2,GCLM,TRIP12,ZNF316,SHPRH,RAE1,SCYL1,NUP54,PAWR,MXD4,DCUN1D4,PIP4K2A,GFM2,SPPL2A,FASTKD3,FGFR3,GRK2,KLHL20,KMT5A,PPIG,RRBP1,NABP2,DUS2,ANP32A,NDUFS8,FBL,ERI3,STAT3,SLC35A1,MYO5A,AMPD2,B3GALT6,TGFB1,ELOVL5,PPP1R9B,DCAF6,HEMK1,HELB,PSPC1,MIER1,NADK2,RFFL,RCOR1,PRMT2,CDK11A,TFEB,MTMR3,CTSL,UPF1,ZC3H7B,DTX4,KMT2B,ACAT1,ZMIZ1,PLOD3,HRAS,TERF1,SLF2,RAB14,FGFR1OP,ADD1,KDM4A,MRPS15,MAP3K7CL,PIGQ,AGPAT1,XIAP,DHX8,GLUD1,EDRF1,PABPC4,CDK5,PSMD1,CIPC,NEK6,NSRP1,SRSF4,PDS5B,FNIP2,NUP153,SENP1,KCNAB2,PCBP2,PGAP2,PLK3,ZNF672,TMEM115,MRPL43,TOPORS,DCUN1D5,ICMT,STOML2,BRMS1,ZNF689,AXIN1,LIMK1,ATE1,VIPAS39,MLYCD,ST3GAL2,SMG9,FBXL3,TFDP2,E2F2,LONP2,AAAS,PFKP,DDX42,SSRP1,NDUFV2,MRPL9,MRPS2,CERK,TOP2B,EZH1,ZNRF3,MCTS1,RAVER2,DDRGK1,GNS,DDX56,EIF2S2,INTS7,INPP5A,MCM5,RTCB,ZNF326,FOXN2,CARS2,UBE2QL1,NAGPA,ETV3,RB1CC1,DHX29,ZMYND11,PGS1,MAN1B1,TEX10,MYBL2,RPS10,ARMT1,SRSF5,CBFA2T2,MPG,ABCF1,CYB5A,PTPRF,SCARB2,POLR2J,DUSP3,CSK,SETD3,TEX30,PTAR1,MDH1,CNOT6,PLPP6,HEXA,SGF29,RNF139,EGLN1,ZNF296,ABCA3,SARNP,TRERF1,IVNS1ABP,UBR2,CHD1L,RMI2,WDTC1,MYH9,CREBL2,RXYLT1,NIT2,ZNF267,EFL1,SAFB2,PRKACA,TCF19,STAM,KTN1,APP,ANKIB1,PRKD3,SP100,ZKSCAN1,UTP18,GRSF1,DUT,DDA1,NUP107,ANAPC7,RNF19A,MAVS,ATF2,RBM15,CLN6,RNF169,ADCY7,ENPP4,INTS13,MAP4K4,RNPS1,WBP2,ATP6V0A1,NDUFA7,TAZ,FKBP3,DDX17,TAF2,CHCHD3,PEX5,CDC16,HIPK2,NT5C3B,RPLP1,RBMS1,MBOAT1,PDXK,FUS,GEN1,ZBTB11,LRP8,GALK1,ZNF786,RPS2,TRAK1,JMJD6,UBE4A,ETS1,PLPP5,PNO1,ZNF92,KRI1,FBXO3,CAPN2,ERH,SUV39H2,GATC,NDUFB4,PPP1R8,PRDM4,DCP1A,GTSE1,GEMIN6,TTLL12,HNRNPM,LYPLA2,IMPA2,LDHB,PDPK1,PPP3CA,TK1,GUK1,TNFAIP3,GALC,POLK,ZNF512,MRPS10,MTMR12,DDX39A,PDE3B,RPA1,ZNF862,ZNF180,KEAP1,POLE,TATDN2,PITX1,MAPK6,CAPN7,LRPPRC,PML,SLC25A19,HMGB2,PSAP,USF2,ANAPC4,FAF1,SNAPIN,SRM,COX15,DDX47,AGRN,THOC1,GPBP1L1,GNPDA1,PPP1R15B,MCCC1,CSNK2A1,EBNA1BP2,CDIPT,BIRC2,LIN9,ABL2,PCNA,ZNF639,ETV6,TRMU,PIK3R2,XRCC2,PPCDC,MCMBP,MYBL1,MRPL32,CCAR1,ABCC5,PTPRK,CDC37,SP3,METTL1,EXOSC6,HARS,BAZ2A,TLK1,MRPL12,GMFB,EZR,LRP5,BRCA1,ESYT1,PRKRA,TONSL,NAGLU,SOCS4,QRSL1,ACTB,DHFR2,OSGEPL1,ZNF45,NUDT11,NAA60,GEMIN7,SEPHS2,TMUB1,CTCF,ASAH1,PPP3CB,B4GALT4,RLF,ASXL2,SNRNP25,RB1,NUS1,MED8,TIGAR,CMTR2,PPIL2,SLC27A4,TIMELESS,MDFIC,MAML1,ALDH18A1,PREB,ABCC1,AACS,UTP15,KRAS,EIF2AK1,RTF1,UBE4B,NFATC2IP,LY6E,EIF4G2,ZDHHC3,ZNF174,PSMC4,SYNCRIP,PALB2,CDC27,PRPS2,TBPL1,PRMT7,ATP5F1A,RNF114,KCTD7,NDUFA5,CYLD,UGP2,FOXM1,MRPL39,DYNLL1,XAB2,SUMO2,ZADH2,GGPS1,DUSP22,RPAIN,COMMD8,RPL11,RAD23A,SEC11A,CSDE1,PDK2,ZBTB21,MDM2,DUS4L,MRPL34,MINPP1,SAP30L,GM2A,DVL2,RPL29,RPL35,PSMA8,COQ10B,BTG2,CPOX,MTMR6,NFATC2,PRPF3,KDM1B,TXNL4A,USP36,RPSA,SRSF1,MRPL2,DNAJC10,CLK3,ZNF700,SCAP,MAFK,PSMD3,NDUFA11,ZNF436,DNAJC17,NCOA1,LTA4H,AP2S1,SLC25A39,USP53,ZC3HC1,INTS2,CTDP1,CDC40,RRP15,CDT1,GNE,ARID5A,SMC6,NKRF,SUMF1,CHAC2,GGA2,CSNK1A1,RMI1,TFRC,WRNIP1,PTPN2,IRF4,GSTK1,NDUFV1,CWC27,SS18L1,ABCD1,DDX31,PTGES3,CAMK2G,MLEC,CNTN5,ZNF202,ZMYM5,PPWD1,NEU1,FBXO41,GOLGA7,BIRC5,TFE3,CDCA7L,FAM126A,SPCS3,ACADM,RPS6KC1,UBE2C,SAT2,GCSH,ZNF496,PPCS,NDUFB6,ZDHHC8,NHLRC3,CCNB1,EIF1B,COMMD6,POLR3K,UTP25,SNUPN,PARPBP,RNASEK,CDC25B,MAST2,PLCL2,SPTSSA,DNMT1,SEH1L,AKT2,PBK,NOL8,ELOA,MRNIP,DDX20,GALNT7,AMDHD2,AURKB,CCNF,MCFD2,MAK16,RBM47,STT3A,PSMD8,WDR4,EIF2D,PTPN7,ITGB1,DHTKD1,UQCRH,RRS1,ARRB2,ZNF598,HDAC2,DDX58,WSB2,PPIB,LIME1,MUT,GMFG,CHTF18,ADO,NDUFA4,MAN2B1,PMF1,NOTCH2,METTL3,JMY,CFLAR,NDUFS4,FKBP1A,RNF121,KLF16,HDAC7,ATIC,DAD1,BDH1,CTPS1,ATP6V0A2,PCYT2,RNF135,PIKFYVE,LPCAT1,EEF1D,TERF2,MORC3,PHF10,DDX28,ZNF84,NOA1,PIP4K2C,DCTD,PKM,CYFIP2,KDM3A,PATL1,SF3A2,PSMB3,ADSS,EPRS,ZNF777,SERTAD2,ZFP92,CSNK1G1,QARS,DCK,ACLY,DCAF11,LPCAT4,PPP3R1,VCPIP1,YY1,MAP3K5,RNF14,CDK2,NRBP1,ZC3HAV1,DNMT3A,RWDD1,ZBTB37,RPS6KA1,SF3B1,SUZ12,EIF3D,RAC1,OLA1,KLHL18,ADPGK,SDHA,SDE2,TERF2IP,CRKL,FLAD1,APLP2,ZNF75D,SHC1,KDM2A,UCHL5,TALDO1,NAA35,MRM2,GPX4,RFC3,ERF,TAOK1,CUL3,SLBP,KIAA1586,GALK2,CDC23,POLG2,PSMB9,GAR1,DHX57,CENPU,PRDM11,SOCS7,NSA2,VEZF1,JAK1,PPP2R5A,MRPL55,TBL3,FAAP100,GUCY1B1,H2AFX,STAT1,SEL1L,PPA2,TRIM32,B4GALT3,PDCD11,CSNK1D,ATMIN,POLQ,POU3F2,OTUD5,NCOR2,TWNK,MRI1,TCF3,BABAM1,CDCA3,SLC25A12,BRAP,AGPAT3,MYNN,SDF2L1,BLM,SPR,RAB11A,FOXO3,MAD2L2,PIP5K1C,GTF2F1,RBM17,MAT2B,RPL17,PTEN,CRAT,UPF2,COPS7B,CNOT6L,OSTC,CREB1,MAP3K14,UBE2M,NCOA2,TSHZ1,ZFP64,RNASEH2C,NEK7,TRIR,WDR18,PARP4,ILF3,RPL8,TBRG4,ANAPC2,RHOT1,RPL27A,MARK2,TSR2,ECH1,POLR2A,FBXO21,NUCB1,PLD3,SGSH,HGS,ATP5MC3,TTLL4,PRDX3,HNRNPH3,TFDP1,NAXE,KHSRP,CPEB2,BYSL,ESYT2,DDX52,MIB2,ADA2,PTMS,IER2,UBE2E2,NOP2,DCAF15,NF1,ALKBH5,MOGS,DNAJC24,ZNF107,UBE2Z,SLC29A1,TAF6L,SIRT2,AGFG1,SNRPD3,UBQLN2,USP48,FKBP2,MAPK14,BECN1,SNAPC4,RNF103,EDC3,BCAT2,UBLCP1,MBD4,CYREN,THADA,EIF4A3,METTL14,ATG3,IMPAD1,DPYSL2,PHTF1,SRI,AKR1B1,KHDC4,KIF22,NDUFB9,ZBTB22,JOSD1,NFU1,TECR,OGG1,ARID4A,FGFR1OP2,TIMM50,ELOF1,COPS8,FYTTD1,TDP1,TRIM8,DPM1,RRM2,WDR82,SOX4,STK17B,DHX15,CHAF1A,ABHD5,PAF1,GEMIN5,UBTF,UEVLD,PQBP1,IARS2,GALNT10,ROCK1,COPS6,RPS26,PSMC1,STARD3NL,RPS15,PIGN,ZNF768,UFC1,CIB1,MED13L,MEF2A,EPHX2,SRRT,RHBDD1,NFATC3,ZNF449,BUD31,ZNF335,BCL2,GLTP,YBX1,ACAD8,UBE3C,N4BP2,ZNF189,ALDH9A1,VOPP1,TSTA3,CIC,PSMA1,ISG15,CAND1,GNAS,NAP1L1,RBM25,CDCA5,TRMT10B,NUP62,ZFP90,PITPNA,RBBP4,NANP,NAA20,NIPSNAP2,HNRNPDL,PTDSS1,PDSS2,ZBTB24,MBD1,MMACHC,TOMM20,ASH1L,MPHOSPH8,GNPNAT1,CHERP,WDYHV1,PLAGL2,NSD3,CHKB,IRF3,CHD1,MEAF6,PAIP1,FARSA,ANKLE1,BABAM2,AKAP8,PARL,RPN2,CHTOP,PDIA6,ABI1,SCYL3,TMEM14C,HTRA2,RLIM,ACSL5,CGAS,ZNF500,PSMB7,NLN,NDUFB1,BUD13,PEF1,EIF3G,BTBD1,RAD54B,DAP3,ZNF317,TAB2,CHCHD1,CANT1,SCARB1,USP11,AKNA,SMURF1,TSPAN5,PPP2R2D,CBX4,MIF,CDS2,SH2D3A,MRPL42,CASP6,EYA1,SRGN,MRPS26,DBF4,KLF13,HDDC2,MAN1A1,GART,CTNNBL1,PELO,TANK,BRD7,MRPL11,SLC25A1,SAMD4B,GINS1,ZDHHC18,CSNK1G2,TELO2,GTF3C6,ADAM17,HMGN1,NASP,PRKAR1B,POLR3GL,WDR81,MEN1,ATP5MF,ZNF407,SYMPK,SNRPA,TARS,MAPK3,HSPA1B,CNOT9,ATAD2,PLAA,OSBPL8,COX8A,KBTBD7,ZRANB2,SRSF3,MBD6,TATDN1,IDH3B,PREPL,TYW1B |
| 3.773e-59 | -134.52 | primary metabolic process | biological process | GO:0044238 | 8970 | 1741 | 17256 | 2622 |
ZBTB10,HEXB,TGOLN2,LACTB2,CCNL2,RBM4,ZNF275,FBXO22,EEF2K,RPL23A,USF1,RAD23B,MECR,UPRT,CRY2,ECD,RNF26,ZNRD1,TIPARP,ANKRD9,MGAT5,RHBDD2,FTSJ3,MRPL57,USP34,BAK1,ERCC1,ZNF559,NRAS,GABPA,EHMT1,HNRNPF,WDHD1,MIER2,DIDO1,MCM2,ARF4,GINS4,MID1IP1,SMAD2,RAD18,RPS27A,MYO18A,OGT,COX5A,RNASEL,KLHL42,SMAD1,CHPF2,ZNF75A,SMNDC1,SLC25A33,ZNF720,HIVEP3,CLSPN,GGA1,MUM1,TRIO,DHX9,RAB23,KCTD17,EIF2AK4,PDCD7,PSMD9,APH1B,PARN,CDC73,ATG4A,TFAP4,PDXP,SMC3,RNFT1,FBXO7,EFTUD2,GEMIN4,MRPL21,CPSF4,NUP85,PABPC1,PHKG2,NSUN4,PPA1,LUC7L2,SRSF11,EIF3L,AGGF1,FOXK1,MAPKAPK3,MTA2,SF3B6,ERO1A,TYW1,GTPBP4,USP10,BCLAF1,MRPL16,ELK1,EIF4H,RDH11,FNTA,KPNA1,ETS2,TYW5,WIPI2,ZNF830,CFAP20,ACSF2,NUP58,MRPL3,TRIM41,KARS,PTTG1,STARD7,INO80E,SLC35B2,GLRX3,RCOR3,LCLAT1,CPNE3,ABHD16A,RBM23,FBXL6,ZNF420,MTA1,UBA5,GMEB1,NABP1,NSFL1C,INTS12,ZNF226,GPD1L,ZC3H3,RPRD1B,CGGBP1,PDCL3,CPNE1,ULK3,SEC61B,ERMP1,POLR2L,EID1,KAT7,IDH3A,CRNKL1,RPL38,E2F3,POLR2D,PFKFB3,MEF2D,RAB1A,PPP2CA,ALDH3B1,LSM6,NSMCE2,CAMKMT,RNF38,DMWD,SNRPG,PPP5C,PITRM1,USP13,COMMD10,ZNF445,SRSF6,ZFP91,TRMT6,CCM2,HABP4,ABHD14B,IP6K2,ATP5F1B,WDR5,PMVK,NEXMIF,RRP36,NEIL2,TUT4,PPP1R3B,GOLM1,RPA2,ZBTB45,PSMD2,ITGB8,HUWE1,ZNF260,NAA50,LTN1,KANSL2,UBE3B,ST8SIA2,ZNF710,FBXL19,GTF2H2,RPL22L1,MED22,SPTAN1,DDX24,USP42,LDHA,UTP20,MAGT1,GPS2,ACOX1,PARG,DBI,AEN,PARP10,YWHAH,WDR45B,THAP5,TRIM11,YTHDC2,RBM8A,SND1,RUFY1,FANCI,PAPOLA,ZER1,KRR1,CREM,TET3,FANCL,RAB8A,NUP210,GLIS2,IL6ST,INTS1,SLC44A1,POP7,NOC2L,EIF5,ASB6,RYBP,PLK1,RPP25,PTPN18,RBX1,APH1A,RAD51AP1,SNRPB,CDC6,UBE2V1,PBRM1,EAF2,UTP3,KRTCAP2,ODC1,LUC7L,USP21,ALG3,TRIM4,AGPAT2,CHD3,ZNF367,E2F4,ARRDC1,ADAM9,PRPF4,KPNA2,DVL1,CLN3,BEND6,FAM208A,NGLY1,POT1,ZNF564,FUBP1,RMND5A,CTU2,ZCCHC9,PHB2,CENPF,LAMTOR3,SDC2,CHCHD2,COX4I1,ADCK5,CDK13,RAB6A,CNOT11,ARID1B,C1GALT1,SUB1,MLX,UBE2Q2,CCP110,MBD2,SSBP3,XPA,ZNF746,CTR9,AHCY,ICE2,RBM3,MRPL48,LRSAM1,ABHD2,DCAF8,NSDHL,ACSL3,LDB1,AMD1,MAP4K3,ZNF761,METTL22,ARMC8,STYXL1,RBM38,NMT2,IRF5,RPL36,RXRB,SDHB,PAXX,MBIP,GALNT2,ORMDL2,COX7A2L,ZDHHC7,DTD1,RUVBL2,ECPAS,BCCIP,USP7,SART1,GLT8D1,TRAF7,RPLP2,SUCLG1,ARID2,SLC2A1,LAGE3,ZNF416,ZFYVE21,RRAGC,ATP6V1B2,LYN,PCBP1,ZNF121,MRPL50,VAV1,NRF1,PSMA6,ZNF473,KMT5C,BRPF3,ZNF302,ABRAXAS2,PIN1,PPME1,RPAP1,TARDBP,LMAN1,TOP1MT,AHCYL1,STRAP,SPIDR,CTDSP2,SPSB3,ZNF583,PRPF19,PPIF,KDM3B,MND1,BIRC3,POLR2G,ZNF780B,PPT1,RAB7A,PPIE,NUP155,DCLRE1C,MRPS14,RHBDF2,EIF3H,SUGP1,IDE,DHX16,RBL1,UBXN2B,FASTK,STK38,UHRF2,CHMP4B,XRCC3,H3F3A,CHID1,SMAD4,RAD51D,SLC30A9,NADSYN1,NIFK,MCM10,MTERF1,KLHL21,AGO2,TMX3,CDCA8,GTF3A,ARF1,CDK11B,PAGR1,SCYL2,DNAJB9,HERC3,GTPBP3,CTSS,POLR1B,ORC3,RNLS,RNF5,RBM15B,YTHDC1,RHOA,RPRD1A,HMGN5,PRKDC,TUFM,TOP3A,RANGAP1,PNPLA8,PCGF1,DDX23,PDCD6,NEK1,L3MBTL3,NEIL3,CTBS,BBX,E2F1,IMPDH1,USP20,RBPJ,TAF12,NR2F2,PGAM1,HIPK3,IFI16,TXN,NUP188,MAX,PDCD6IP,GXYLT1,ADAM10,PRKCSH,CXXC1,CUL1,USP39,NANS,GYG1,UBE2I,OAT,MYEF2,PARK7,ASPHD2,PA2G4,NOL11,FIZ1,RAB4A,ZNF200,TRA2B,FBXW2,SUCLG2,AP2B1,TAF5L,SLC26A2,MARCH2,ZNF800,CDC5L,SRSF10,ZNF524,KLF10,NSUN2,LACTB,USP22,CBFB,RFC2,CLNS1A,EIF3A,PRIM1,DOT1L,IWS1,MAP3K4,HHEX,MKNK1,BRD2,RPS14,TPP2,LUC7L3,MRPL27,BTF3,PTPDC1,SLF1,CCDC59,B4GALT2,PTOV1,PRPF38B,RECQL,COX5B,EWSR1,DHPS,POLR2K,GSPT2,PRKAA1,RRM1,TATDN3,B4GALT1,CYCS,SUPT7L,PRPF39,ZNF79,ZNF518A,PSEN1,TMEM165,VPS25,NDUFS7,YY1AP1,CNOT3,NPLOC4,WDR48,RPN1,LHX8,EXOSC7,KLHL5,ZNRF2,PPP4R1,MSH2,DAPK1,TPST1,PIGG,FBXL7,MRPL40,CYC1,MRM3,APOL1,FDFT1,SOCS5,EIF5A,PIGT,PRIM2,CPQ,ELL2,COQ8A,RDH10,USF3,MFNG,ZNF574,RPS24,EXOSC9,ARID1A,ADRB2,MTR,MAP2K2,TWISTNB,PHF6,PI4K2A,XRCC5,DERL1,CAT,GOLGA2,EPOP,RBMX,MED15,PIAS2,USP32,CEBPG,SAMD8,SMPD4,GPI,NUDT3,ZNF511,NDC1,ATXN3,TP53RK,RAB11B,RAF1,C2orf49,SPINDOC,NUDT19,DECR1,CCNA2,SIAH1,MTMR4,ADCY9,LPIN2,SOCS6,MRPS27,TTC3,RNASEH2A,AQR,ILKAP,CDK12,CFL1,SAP30,BRD4,DRAP1,ELP4,EDF1,PKMYT1,ASB13,ERC1,SERP1,TRIM28,SUPT16H,AMZ2,EIF3K,ANKZF1,ZNF282,RAD51C,HINT1,DDOST,DGCR8,CERS6,SAFB,FTSJ1,ATF6,BEND3,XRCC4,EYA2,ADAM23,PRPF4B,NDUFS1,DEPDC1,B4GALT5,MANBA,MECP2,TKT,CBLL1,ARGLU1,SECISBP2,POFUT1,HMG20A,WWP2,EBP,RFWD3,CCNK,DNAJC8,NDUFA2,ELP5,FUT8,PTPN11,AXIN2,MRPL54,FEM1B,RPL19,CARF,CITED2,NDUFA3,MSH6,KAT2A,LONRF3,RFXANK,ADSL,FBXO9,BMS1,KCNQ1,OTUD3,ARSK,GUF1,COMMD4,KLF6,SPPL2B,FADD,CBX3,RPL32,ZHX1,PPP1R11,DUSP11,DDX5,NDUFS5,WDR62,WDR91,TAF6,ESPL1,PURA,DDB1,RORB,POLA2,CCNC,ZNF76,PIGM,KMT2E,UQCR10,PHRF1,UBE2Q1,PTP4A3,COMMD5,ATP5PF,MRPL19,ZNF696,SF3B2,PCYOX1L,CDC42,GOT2,JAZF1,HADHB,RPF2,GPATCH1,TCEA1,SLC35C2,CARM1,SRPK2,DEAF1,LARS,SNRNP200,NCK1,LAP3,VHL,RIOX2,SREK1,SUMF2,PITPNB,KMT2C,PRPSAP1,MPC1,ASF1B,RPL37,MAN2A2,BRWD1,U2SURP,PPM1G,CRCP,CAB39,BAZ1B,STK11,ZNF268,CHEK2,CLU,VPS4A,CHPT1,MRPL13,DCAF5,CAPN1,UBE2D3,NSMCE4A,PPP1R2,PPP1R12A,ZCCHC8,GORASP1,NACA,UBXN1,PCSK7,RPL15,PM20D2,THRAP3,XPNPEP3,TTF1,PRPF18,NUP205,CHKA,LYAR,DTL,MED10,PYURF,TENM3,ZRANB1,CSNK1G3,POLR2I,ERLIN1,NUDT4,SUGP2,RPL6,GBA,SYVN1,EIF2A,VKORC1,CCDC71L,SLTM,DAPK3,MASTL,UAP1,KLHL15,NFIL3,SIAH2,SLC16A1,FN3KRP,CTSA,DNPH1,SNRNP70,APOL2,TSEN15,ADNP2,TCF12,PRKAB1,MDH2,PMS2,UCK2,SMARCA4,UCK1,ORC1,EXT2,MXD1,USP5,HNRNPA2B1,SAP130,RRN3,UBXN2A,IARS,CD3EAP,KIF14,EXOSC1,PPP6C,CS,CYB5R1,UTP4,ZNF770,CSTF1,POU2AF1,HPDL,PGGT1B,RNF25,METTL2A,SMU1,PCGF6,ATXN1,LSM8,GLO1,OGDH,EDEM2,TOLLIP,FANCE,MBD3,RPS9,PDHX,PON2,DUS3L,HNRNPR,STAT6,ARNTL,FKBP5,BRD9,MAPK1,ABCA1,CWC25,PDF,NAT14,DNAJC2,GCLM,TRIP12,ZNF316,SHPRH,RAE1,SCYL1,NUP54,PAWR,MXD4,DCUN1D4,PIP4K2A,GFM2,SPPL2A,FASTKD3,FGFR3,GRK2,KLHL20,KMT5A,PPIG,RRBP1,NABP2,DUS2,ANP32A,NDUFS8,FBL,ERI3,STAT3,SLC35A1,MYO5A,AMPD2,B3GALT6,TGFB1,ELOVL5,PPP1R9B,DCAF6,HEMK1,HELB,PSPC1,MIER1,NADK2,RFFL,RCOR1,PRMT2,CDK11A,TFEB,MTMR3,CTSL,UPF1,ZC3H7B,DTX4,KMT2B,ACAT1,ZMIZ1,PLOD3,HRAS,TERF1,SLF2,RAB14,FGFR1OP,ADD1,KDM4A,MRPS15,MAP3K7CL,PIGQ,AGPAT1,XIAP,DHX8,GLUD1,EDRF1,PABPC4,CDK5,PSMD1,CIPC,NEK6,NSRP1,SRSF4,PDS5B,FNIP2,NUP153,SENP1,KCNAB2,PCBP2,PGAP2,PLK3,ZNF672,TMEM115,MRPL43,TOPORS,DCUN1D5,ICMT,STOML2,BRMS1,ZNF689,AXIN1,LIMK1,ATE1,VIPAS39,MLYCD,ST3GAL2,SMG9,FBXL3,TFDP2,E2F2,LONP2,AAAS,PFKP,DDX42,SSRP1,NDUFV2,MRPL9,MRPS2,CERK,TOP2B,EZH1,ZNRF3,MCTS1,RAVER2,DDRGK1,DDX56,EIF2S2,INTS7,INPP5A,MCM5,RTCB,ZNF326,FOXN2,CARS2,UBE2QL1,NAGPA,ETV3,RB1CC1,DHX29,PGS1,ZMYND11,MAN1B1,TEX10,MYBL2,RPS10,ARMT1,SRSF5,CBFA2T2,MPG,ABCF1,CYB5A,PTPRF,SCARB2,POLR2J,DUSP3,CSK,SETD3,TEX30,PTAR1,MDH1,CNOT6,PLPP6,HEXA,SGF29,RNF139,EGLN1,ZNF296,SARNP,ABCA3,TRERF1,IVNS1ABP,UBR2,CHD1L,RMI2,WDTC1,MYH9,CREBL2,NIT2,RXYLT1,EFL1,ZNF267,SAFB2,PRKACA,TCF19,STAM,APP,KTN1,ANKIB1,PRKD3,SP100,ZKSCAN1,UTP18,DUT,GRSF1,DDA1,NUP107,ANAPC7,MAVS,RNF19A,ATF2,RBM15,CLN6,RNF169,ADCY7,ENPP4,INTS13,MAP4K4,RNPS1,WBP2,ATP6V0A1,NDUFA7,TAZ,FKBP3,DDX17,TAF2,CHCHD3,PEX5,CDC16,HIPK2,NT5C3B,RPLP1,RBMS1,MBOAT1,FUS,GEN1,ZBTB11,LRP8,GALK1,ZNF786,RPS2,TRAK1,JMJD6,UBE4A,ETS1,PLPP5,ZNF92,PNO1,KRI1,FBXO3,CAPN2,ERH,SUV39H2,GATC,NDUFB4,PPP1R8,PRDM4,DCP1A,GTSE1,GEMIN6,TTLL12,HNRNPM,LYPLA2,IMPA2,LDHB,PDPK1,PPP3CA,TK1,GUK1,TNFAIP3,GALC,POLK,ZNF512,MRPS10,MTMR12,DDX39A,PDE3B,RPA1,ZNF862,ZNF180,KEAP1,POLE,TATDN2,PITX1,MAPK6,CAPN7,LRPPRC,PML,HMGB2,PSAP,USF2,ANAPC4,FAF1,SNAPIN,COX15,DDX47,THOC1,AGRN,GNPDA1,GPBP1L1,PPP1R15B,MCCC1,CSNK2A1,EBNA1BP2,CDIPT,BIRC2,LIN9,ABL2,PCNA,ZNF639,ETV6,TRMU,PIK3R2,XRCC2,PPCDC,MCMBP,MYBL1,MRPL32,CCAR1,PTPRK,CDC37,SP3,METTL1,EXOSC6,BAZ2A,HARS,TLK1,MRPL12,GMFB,LRP5,BRCA1,ESYT1,PRKRA,TONSL,SOCS4,QRSL1,ACTB,DHFR2,OSGEPL1,ZNF45,NUDT11,NAA60,GEMIN7,SEPHS2,TMUB1,ASAH1,CTCF,PPP3CB,B4GALT4,RLF,ASXL2,SNRNP25,RB1,NUS1,MED8,CMTR2,PPIL2,SLC27A4,TIMELESS,MDFIC,MAML1,ALDH18A1,PREB,AACS,UTP15,KRAS,EIF2AK1,RTF1,UBE4B,NFATC2IP,LY6E,EIF4G2,ZDHHC3,ZNF174,PSMC4,SYNCRIP,PALB2,CDC27,PRPS2,TBPL1,PRMT7,ATP5F1A,RNF114,KCTD7,NDUFA5,CYLD,UGP2,FOXM1,MRPL39,DYNLL1,XAB2,SUMO2,ZADH2,GGPS1,DUSP22,RPAIN,COMMD8,RPL11,RAD23A,SEC11A,CSDE1,PDK2,ZBTB21,MDM2,DUS4L,MRPL34,MINPP1,SAP30L,GM2A,DVL2,RPL29,RPL35,PSMA8,BTG2,CPOX,MTMR6,NFATC2,PRPF3,KDM1B,TXNL4A,USP36,RPSA,SRSF1,MRPL2,DNAJC10,CLK3,ZNF700,SCAP,MAFK,PSMD3,NDUFA11,ZNF436,DNAJC17,NCOA1,LTA4H,AP2S1,USP53,ZC3HC1,INTS2,CTDP1,CDC40,RRP15,CDT1,GNE,ARID5A,SMC6,NKRF,SUMF1,GGA2,CSNK1A1,RMI1,WRNIP1,PTPN2,IRF4,NDUFV1,CWC27,SS18L1,ABCD1,DDX31,PTGES3,CAMK2G,MLEC,CNTN5,ZNF202,ZMYM5,PPWD1,NEU1,FBXO41,GOLGA7,BIRC5,TFE3,CDCA7L,FAM126A,SPCS3,ACADM,RPS6KC1,UBE2C,GCSH,ZNF496,PPCS,NDUFB6,ZDHHC8,NHLRC3,CCNB1,EIF1B,COMMD6,POLR3K,UTP25,SNUPN,PARPBP,RNASEK,CDC25B,MAST2,PLCL2,SPTSSA,DNMT1,SEH1L,AKT2,PBK,NOL8,ELOA,MRNIP,DDX20,GALNT7,AMDHD2,AURKB,CCNF,MCFD2,MAK16,RBM47,STT3A,PSMD8,WDR4,EIF2D,PTPN7,DHTKD1,UQCRH,RRS1,ARRB2,ZNF598,HDAC2,DDX58,WSB2,PPIB,LIME1,MUT,GMFG,CHTF18,ADO,NDUFA4,MAN2B1,PMF1,NOTCH2,METTL3,JMY,CFLAR,NDUFS4,FKBP1A,RNF121,KLF16,HDAC7,ATIC,DAD1,CTPS1,ATP6V0A2,PCYT2,RNF135,PIKFYVE,LPCAT1,EEF1D,TERF2,MORC3,PHF10,DDX28,ZNF84,NOA1,PIP4K2C,DCTD,PKM,CYFIP2,KDM3A,PATL1,SF3A2,PSMB3,ADSS,EPRS,ZNF777,SERTAD2,ZFP92,CSNK1G1,QARS,DCK,ACLY,DCAF11,LPCAT4,PPP3R1,VCPIP1,YY1,MAP3K5,RNF14,CDK2,NRBP1,ZC3HAV1,DNMT3A,RWDD1,ZBTB37,RPS6KA1,SF3B1,SUZ12,EIF3D,RAC1,OLA1,KLHL18,ADPGK,SDHA,SDE2,TERF2IP,CRKL,FLAD1,APLP2,ZNF75D,SHC1,KDM2A,UCHL5,TALDO1,NAA35,MRM2,GPX4,RFC3,ERF,TAOK1,CUL3,SLBP,KIAA1586,GALK2,CDC23,POLG2,PSMB9,GAR1,DHX57,CENPU,PRDM11,SOCS7,NSA2,VEZF1,JAK1,PPP2R5A,MRPL55,TBL3,FAAP100,GUCY1B1,H2AFX,STAT1,SEL1L,PPA2,TRIM32,B4GALT3,PDCD11,CSNK1D,ATMIN,POLQ,POU3F2,OTUD5,NCOR2,TWNK,MRI1,TCF3,BABAM1,CDCA3,SLC25A12,BRAP,AGPAT3,MYNN,SDF2L1,BLM,RAB11A,FOXO3,MAD2L2,PIP5K1C,GTF2F1,RBM17,RPL17,PTEN,CRAT,UPF2,COPS7B,CNOT6L,OSTC,CREB1,MAP3K14,UBE2M,NCOA2,TSHZ1,ZFP64,RNASEH2C,NEK7,TRIR,WDR18,PARP4,ILF3,RPL8,TBRG4,ANAPC2,RHOT1,RPL27A,MARK2,TSR2,ECH1,POLR2A,FBXO21,NUCB1,PLD3,SGSH,HGS,ATP5MC3,TTLL4,PRDX3,HNRNPH3,TFDP1,NAXE,KHSRP,CPEB2,BYSL,ESYT2,DDX52,MIB2,ADA2,PTMS,IER2,UBE2E2,NOP2,DCAF15,NF1,ALKBH5,MOGS,DNAJC24,ZNF107,UBE2Z,SLC29A1,TAF6L,SIRT2,SNRPD3,UBQLN2,USP48,FKBP2,MAPK14,BECN1,SNAPC4,RNF103,EDC3,BCAT2,UBLCP1,MBD4,CYREN,THADA,EIF4A3,METTL14,ATG3,IMPAD1,DPYSL2,PHTF1,SRI,AKR1B1,KHDC4,KIF22,NDUFB9,ZBTB22,JOSD1,NFU1,TECR,OGG1,ARID4A,FGFR1OP2,TIMM50,ELOF1,COPS8,TDP1,TRIM8,DPM1,RRM2,WDR82,SOX4,STK17B,DHX15,CHAF1A,ABHD5,PAF1,GEMIN5,UBTF,UEVLD,PQBP1,IARS2,GALNT10,ROCK1,COPS6,RPS26,PSMC1,STARD3NL,RPS15,PIGN,ZNF768,UFC1,CIB1,MED13L,MEF2A,EPHX2,SRRT,RHBDD1,NFATC3,ZNF449,ZNF335,BUD31,BCL2,GLTP,YBX1,ACAD8,UBE3C,N4BP2,ZNF189,VOPP1,TSTA3,CIC,PSMA1,ISG15,CAND1,GNAS,NAP1L1,RBM25,CDCA5,TRMT10B,NUP62,ZFP90,PITPNA,RBBP4,NANP,NAA20,NIPSNAP2,HNRNPDL,PTDSS1,PDSS2,ZBTB24,MBD1,TOMM20,ASH1L,MPHOSPH8,GNPNAT1,CHERP,WDYHV1,PLAGL2,NSD3,CHKB,IRF3,CHD1,MEAF6,PAIP1,FARSA,ANKLE1,BABAM2,AKAP8,PARL,RPN2,CHTOP,PDIA6,ABI1,SCYL3,HTRA2,RLIM,ACSL5,CGAS,ZNF500,PSMB7,NLN,NDUFB1,BUD13,PEF1,EIF3G,BTBD1,RAD54B,DAP3,ZNF317,TAB2,CHCHD1,CANT1,SCARB1,USP11,AKNA,SMURF1,TSPAN5,PPP2R2D,CBX4,MIF,CDS2,SH2D3A,MRPL42,CASP6,EYA1,SRGN,MRPS26,DBF4,KLF13,HDDC2,MAN1A1,GART,CTNNBL1,PELO,TANK,BRD7,MRPL11,SLC25A1,SAMD4B,GINS1,ZDHHC18,CSNK1G2,TELO2,GTF3C6,ADAM17,HMGN1,NASP,PRKAR1B,POLR3GL,WDR81,MEN1,ATP5MF,ZNF407,SYMPK,SNRPA,TARS,MAPK3,HSPA1B,CNOT9,ATAD2,PLAA,OSBPL8,COX8A,KBTBD7,ZRANB2,SRSF3,MBD6,TATDN1,IDH3B,PREPL,TYW1B |
| 1.568e-58 | -133.10 | KINSEY_TARGETS_OF_EWSR1_FLII_FUSION_UP | MSigDB lists | KINSEY_TARGETS_OF_EWSR1_FLII_FUSION_UP | 1171 | 389 | 17377 | 2626 |
RAB14,ZNF496,MRPS15,DHX8,CUL1,USP39,CCNB1,SLC20A1,PPP1R16B,MIS12,FBXO22,PA2G4,PSMD1,DBNDD1,PDS5B,TRA2B,FNIP2,NUP153,DNMT1,ANKRD9,SEH1L,SRSF10,CDC5L,NOL12,SRP72,NRAS,AATF,MKI67,HNRNPF,KIF15,WDHD1,AURKB,SMC2,DIDO1,ICMT,CCNF,MCM2,RFC2,GINS4,PLEKHF2,PRIM1,RAD18,KIF18B,WDR4,C1orf109,RRS1,E2F2,PFKP,SLC25A33,SVIP,SSRP1,NXT2,HSPH1,MAPRE1,POLR2K,PRKAA1,C16orf87,ANKH,RAB23,RRM1,KIF23,CYCS,HAUS4,ZNRF3,EIF2S2,SMC3,SLC38A5,ARPC5,MCM5,MSH2,GEMIN4,NSUN4,PPA1,NUP85,TMED2,EIF5A,IFRD1,PRIM2,MYBL2,USP10,EXOSC9,UHRF1BP1,GORASP2,CAPZA2,C9orf40,PATL1,MAP2K2,MATR3,CYB5A,XRCC5,FAS,ADSS,PTPRF,SLCO4A1,MTHFD2,FNTA,KPNA1,CCDC86,ETS2,DCK,ACLY,FAM83D,PIAS2,SLAIN1,CDK2,ZNF207,POC1A,PTTG1,RAC1,TPX2,TMEM97,RMI2,NUF2,C19orf48,GLRX3,TCF19,ARL6IP6,CRKL,PRKD3,ATP2A2,MTMR4,UCHL5,GRSF1,NSFL1C,ANKRD13C,RNASEH2A,FAM76B,CLN6,CDKN2AIP,CCT2,RFC3,IDH3A,CUL3,POLR2D,SLBP,NUSAP1,CDCA2,GALK2,PKMYT1,RAB1A,SERP1,MAT2A,TAF2,KIF2A,RAD51C,ACYP1,SAFB,PPA2,PPP5C,GEN1,LRP8,COIL,POLQ,POU3F2,COMMD10,RPS2,MZT1,PKP4,DEPDC1,C1orf112,TRMT6,FAM76A,TKT,CDCA3,GMCL1,WDR5,BLM,WRB,PNO1,EBP,MAT2B,RFWD3,SUV39H2,CENPJ,PPP1R8,FJX1,PTPN11,PRC1,NAA50,GTSE1,FEM1B,NAP1L4,GTF2H2,IMPA2,MSH6,TMX1,SMC4,TK1,TACC1,NET1,ZNF512,ILF3,MRPS10,RAB3IP,DDX39A,KIF11,TTC33,RPA1,SLC19A1,KIF18A,ZHX1,PRDX3,STX18,TFDP1,MAPK6,C4orf46,AEN,HMGB2,WDR76,YWHAH,ESPL1,VPS29,SNAPIN,POLA2,CCNC,ZNF76,SKA3,HNRNPAB,ALKBH5,ZNF107,CSNK2A1,ABCB10,SLC29A1,KIF2C,CDC42SE2,BRIX1,MRPL19,FANCI,KRR1,MBD4,LIN9,RAB8A,RAP1A,PCNA,ZNF639,JOSD1,TCEA1,MYBL1,MCMBP,TACC3,SRPK2,PLK1,RPP25,LARS,CCDC138,RAD51AP1,TLK1,RRM2,PSMG1,CKAP2L,CDC6,BRCA1,PBRM1,EAF2,ANLN,LUC7L,USP21,DHX15,ASF1B,RHEB,CHAF1A,EPB41,GEMIN5,CDCA4,FBXO28,NIP7,ZNF367,QRSL1,ACTB,PRPF4,KPNA2,CHEK2,FUBP1,PPP1R2,HJURP,ZCCHC8,CENPF,RACGAP1,CDK13,XPNPEP3,DNAJB1,XPO7,CRLF3,TTF1,NUP205,DTL,NFATC3,MLX,MED8,KIF13B,ZNF746,TIMELESS,YBX1,KNTC1,MRPL48,GLE1,N4BP2,NUDT4,UBE4B,EIF2A,APPL1,ANKRD46,MASTL,HAUS8,UAP1,PRPS2,CDCA5,SLC16A1,NUP62,RBBP4,NANP,CCNB2,TSEN15,NIPA1,BCCIP,FOXM1,WDYHV1,MRPL39,UCK2,TM9SF3,ORC1,PCBP1,RAD23A,VAV1,MRPL50,OIP5,DUS4L,KIF14,PPP6C,POC5,CSTF1,PPIF,MND1,ARHGAP17,MTMR6,DNAJC9,BOLA1,NUP155,RAD54B,SRSF1,GLOD4,HNRNPR,PROSER1,CEP55,ANP32E,AKNA,PPP2R2D,SMAD4,CMAS,MCM10,MRPL42,CDT1,DBF4,CDCA8,SMC6,PAWR,ARF1,GGA2,NCAPG,RMI1,GFM2,FBXO5,FASTKD3,KIF5B,GART,SLC1A4,ANP32A,CENPM,GINS1,PHF20L1,RPRD1A,FAM49B,HMGN5,ASPM,PRKDC,ABCF2,CCDC34,RCOR1,RANGAP1,SNRPA,LEMD2,PLAA,ATAD2,BIRC5,NEIL3,PGRMC1,E2F1,SRSF3,NR2F2 |
| 2.273e-57 | -130.43 | cellular nitrogen compound metabolic process | biological process | GO:0034641 | 5144 | 1135 | 17256 | 2622 |
ZBTB10,HEXB,LACTB2,CCNL2,RBM4,ZNF275,EEF2K,RPL23A,USF1,RAD23B,UPRT,CRY2,ECD,ZNRD1,FTSJ3,MRPL57,ERCC1,ZNF559,GABPA,EHMT1,HNRNPF,WDHD1,MIER2,DIDO1,MCM2,GINS4,SMAD2,RAD18,RPS27A,MYO18A,COX5A,RNASEL,SMAD1,ZNF75A,OAZ1,SMNDC1,SLC25A33,HIVEP3,CLSPN,MUM1,DHX9,RAB23,PDCD7,PARN,CDC73,TFAP4,PDXP,SMC3,EFTUD2,GEMIN4,MRPL21,CPSF4,PABPC1,NSUN4,PPA1,LUC7L2,SRSF11,EIF3L,AGGF1,FOXK1,MTA2,SF3B6,TYW1,GTPBP4,USP10,BCLAF1,MRPL16,ELK1,EIF4H,KPNA1,ETS2,TYW5,ZNF830,MRPL3,KARS,NQO1,PTTG1,SLC35B2,INO80E,RCOR3,RBM23,ZNF420,MTA1,GMEB1,NABP1,INTS12,ZNF226,GPD1L,ZC3H3,RPRD1B,CGGBP1,PDCL3,CPNE1,POLR2L,EID1,KAT7,CRNKL1,RPL38,E2F3,POLR2D,MEF2D,PPP2CA,LSM6,NSMCE2,SNRPG,PPP5C,COMMD10,ZNF445,SRSF6,TRMT6,HABP4,ABHD14B,ATP5F1B,WDR5,NEXMIF,RRP36,NEIL2,TUT4,RPA2,ZBTB45,CLIC4,ITGB8,HUWE1,ZNF260,LTN1,ST8SIA2,ZNF710,GTF2H2,RPL22L1,MED22,DDX24,LDHA,UTP20,SLC19A1,PARG,AEN,PARP10,THAP5,YTHDC2,RBM8A,SND1,FANCI,PAPOLA,KRR1,CREM,TET3,FANCL,GLIS2,INTS1,SLC44A1,POP7,NOC2L,EIF5,RYBP,RPP25,RBX1,APH1A,RAD51AP1,SNRPB,CDC6,UBE2V1,PBRM1,EAF2,UTP3,ODC1,LUC7L,USP21,CHD3,ZNF367,E2F4,PRPF4,KPNA2,DVL1,CLN3,BEND6,FAM208A,POT1,ZNF564,FUBP1,CTU2,ZCCHC9,PHB2,CENPF,CHCHD2,COX4I1,CDK13,CNOT11,RSAD1,ARID1B,SUB1,MLX,MBD2,SSBP3,XPA,ZNF746,CTR9,AHCY,RBM3,ICE2,MRPL48,LDB1,AMD1,ZNF761,RBM38,IRF5,RXRB,RPL36,PAXX,MBIP,ORMDL2,COX7A2L,DTD1,RUVBL2,BCCIP,USP7,SART1,TRAF7,RPLP2,SUCLG1,ARID2,LAGE3,ZNF416,RRAGC,ATP6V1B2,PCBP1,ZNF121,MRPL50,NRF1,ZNF473,KMT5C,ZNF302,RPAP1,TARDBP,TOP1MT,AHCYL1,STRAP,SPIDR,ZNF583,PRPF19,KDM3B,MND1,POLR2G,ZNF780B,PPIE,DCLRE1C,MRPS14,EIF3H,SUGP1,IDE,DHX16,RBL1,UHRF2,XRCC3,SMAD4,RAD51D,SLC30A9,NADSYN1,NIFK,MCM10,MTERF1,AGO2,GTF3A,PAGR1,GTPBP3,POLR1B,ORC3,RNLS,RBM15B,YTHDC1,RHOA,RPRD1A,HMGN5,PRKDC,TUFM,TOP3A,PCGF1,HAGH,DDX23,L3MBTL3,NEIL3,BBX,E2F1,IMPDH1,RBPJ,TAF12,NR2F2,PGAM1,HIPK3,IFI16,TXN,MAX,CXXC1,USP39,NANS,UBE2I,MYEF2,PARK7,PA2G4,NOL11,FIZ1,ZNF200,TRA2B,TAF5L,SLC26A2,ZNF800,CDC5L,SRSF10,ZNF524,KLF10,NSUN2,USP22,CBFB,RFC2,CLNS1A,EIF3A,PRIM1,DOT1L,IWS1,HHEX,BRD2,RPS14,LUC7L3,MRPL27,BTF3,SLF1,CCDC59,PTOV1,PRPF38B,RECQL,COX5B,EWSR1,DHPS,POLR2K,PRKAA1,GSPT2,RRM1,TATDN3,CYCS,SUPT7L,PRPF39,ZNF79,ZNF518A,PSEN1,VPS25,NDUFS7,YY1AP1,CNOT3,NPLOC4,WDR48,LHX8,EXOSC7,MSH2,TPST1,MRPL40,CYC1,MRM3,EIF5A,PRIM2,CPQ,ELL2,ZNF574,RPS24,EXOSC9,ARID1A,TWISTNB,PHF6,XRCC5,MTHFD2,RBMX,MED15,PIAS2,CEBPG,SAMD8,SMPD4,GPI,NUDT3,ZNF511,ATXN3,TP53RK,UROD,C2orf49,SPINDOC,LPIN2,ADCY9,MRPS27,RNASEH2A,AQR,CDK12,SAP30,BRD4,DRAP1,ELP4,EDF1,TRIM28,SUPT16H,EIF3K,ZNF282,RAD51C,HINT1,DGCR8,CERS6,SAFB,FTSJ1,ATF6,BEND3,XRCC4,EYA2,PRPF4B,NDUFS1,DEPDC1,MECP2,TKT,ARGLU1,SECISBP2,HMG20A,WWP2,RFWD3,CCNK,DNAJC8,NDUFA2,ELP5,FUT8,AXIN2,MRPL54,RPL19,CARF,CITED2,NDUFA3,MSH6,KAT2A,RFXANK,ADSL,BMS1,KCNQ1,COMMD4,KLF6,GUF1,SPPL2B,CBX3,RPL32,ZHX1,OAZ2,DUSP11,DDX5,NDUFS5,WDR62,TAF6,PURA,DDB1,RORB,POLA2,CCNC,ZNF76,KMT2E,UQCR10,PHRF1,COMMD5,ATP5PF,MRPL19,ZNF696,SF3B2,JAZF1,RPF2,GPATCH1,TCEA1,CARMIL1,CARM1,SRPK2,DEAF1,LARS,SNRNP200,RIOX2,SREK1,KMT2C,PRPSAP1,MPC1,ASF1B,RPL37,BRWD1,U2SURP,CRCP,BAZ1B,ZNF268,CHEK2,CLU,MRPL13,UBE2D3,NSMCE4A,ZCCHC8,NACA,PCSK7,RPL15,PM20D2,THRAP3,TTF1,PRPF18,CHKA,LYAR,DTL,MED10,ATP5IF1,POLR2I,NUDT4,SUGP2,RPL6,GBA,EIF2A,SLTM,DAPK3,UAP1,NFIL3,DNPH1,SNRNP70,TSEN15,ADNP2,TCF12,MDH2,PMS2,UCK2,SMARCA4,UCK1,ORC1,MXD1,HNRNPA2B1,SAP130,RRN3,IARS,CD3EAP,EXOSC1,UTP4,ZNF770,CSTF1,POU2AF1,METTL2A,SMU1,PCGF6,LSM8,ATXN1,GLO1,OGDH,MBD3,FANCE,RPS9,PDHX,DUS3L,HNRNPR,STAT6,ARNTL,MAPK1,BRD9,CWC25,PDF,NAT14,DNAJC2,GCLM,TRIP12,ZNF316,SHPRH,SCYL1,PAWR,MXD4,GFM2,SPPL2A,KMT5A,PPIG,RRBP1,DUS2,NABP2,ANP32A,NDUFS8,ERI3,FBL,STAT3,AMPD2,TGFB1,PPP1R9B,HEMK1,PSPC1,HELB,MIER1,NADK2,RCOR1,TFEB,UPF1,ZC3H7B,KMT2B,ACAT1,ZMIZ1,SLF2,TERF1,MRPS15,KDM4A,DHX8,EDRF1,PABPC4,CIPC,NSRP1,SRSF4,PDS5B,PCBP2,KCNAB2,ZNF672,MRPL43,TOPORS,STOML2,BRMS1,ZNF689,VIPAS39,SMG9,TFDP2,E2F2,PFKP,SSRP1,DDX42,NDUFV2,MRPL9,MRPS2,CERK,TOP2B,EZH1,RAVER2,MCTS1,DDX56,EIF2S2,INTS7,MCM5,ZNF326,RTCB,FOXN2,CARS2,ETV3,RB1CC1,DHX29,ZMYND11,TEX10,MYBL2,RPS10,SRSF5,MPG,CBFA2T2,ABCF1,POLR2J,SETD3,MDH1,CNOT6,SGF29,ZNF296,SARNP,TRERF1,IVNS1ABP,UBR2,CHD1L,RMI2,CREBL2,NIT2,EFL1,ZNF267,SAFB2,PRKACA,TCF19,APP,SP100,ZKSCAN1,UTP18,DUT,GRSF1,CLN6,RBM15,ATF2,ADCY7,ENPP4,INTS13,RNPS1,WBP2,ATP6V0A1,NDUFA7,TAZ,DDX17,CHCHD3,TAF2,NT5C3B,HIPK2,RPLP1,RBMS1,FUS,PDXK,ZBTB11,GEN1,ZNF786,GALK1,RPS2,JMJD6,ETS1,ZNF92,PNO1,KRI1,ERH,SUV39H2,GATC,NDUFB4,PPP1R8,PRDM4,DCP1A,GEMIN6,HNRNPM,LDHB,PDPK1,TK1,GUK1,POLK,GALC,ZNF512,MRPS10,PDE3B,DDX39A,RPA1,ZNF180,ZNF862,KEAP1,POLE,TATDN2,PITX1,PML,LRPPRC,SLC25A19,HMGB2,USF2,SRM,COX15,DDX47,THOC1,GNPDA1,GPBP1L1,MCCC1,CSNK2A1,EBNA1BP2,BIRC2,LIN9,PCNA,ZNF639,ETV6,TRMU,XRCC2,PPCDC,MYBL1,MCMBP,CCAR1,MRPL32,METTL1,SP3,EXOSC6,BAZ2A,HARS,MRPL12,BRCA1,PRKRA,TONSL,QRSL1,DHFR2,ZNF45,OSGEPL1,NUDT11,GEMIN7,SEPHS2,ASAH1,CTCF,RLF,ASXL2,SNRNP25,RB1,MED8,CMTR2,TIMELESS,MDFIC,MAML1,PREB,UTP15,RTF1,EIF4G2,ZNF174,SYNCRIP,PALB2,PRPS2,TBPL1,PRMT7,ATP5F1A,NDUFA5,CYLD,UGP2,FOXM1,XAB2,DYNLL1,MRPL39,SUMO2,RPAIN,COMMD8,RPL11,RAD23A,CSDE1,SEC11A,ZBTB21,DUS4L,MRPL34,SAP30L,GM2A,DVL2,RPL29,RPL35,BTG2,CPOX,NFATC2,PRPF3,KDM1B,TXNL4A,RPSA,SRSF1,MRPL2,ZNF700,MAFK,NDUFA11,DNAJC17,ZNF436,NCOA1,LTA4H,SLC25A39,INTS2,CTDP1,CDC40,RRP15,CDT1,GNE,ARID5A,SMC6,NKRF,CHAC2,RMI1,WRNIP1,IRF4,GSTK1,NDUFV1,CWC27,SS18L1,DDX31,PTGES3,ZNF202,ZMYM5,PPWD1,NEU1,BIRC5,TFE3,CDCA7L,ACADM,SPCS3,SAT2,GCSH,PPCS,ZNF496,NDUFB6,CCNB1,EIF1B,COMMD6,POLR3K,UTP25,SNUPN,PARPBP,RNASEK,SPTSSA,DNMT1,NOL8,ELOA,MRNIP,DDX20,AMDHD2,MAK16,RBM47,EIF2D,WDR4,DHTKD1,UQCRH,RRS1,ARRB2,ZNF598,HDAC2,LIME1,CHTF18,NDUFA4,NOTCH2,PMF1,METTL3,JMY,NDUFS4,KLF16,ATIC,HDAC7,CTPS1,ATP6V0A2,EEF1D,TERF2,DDX28,PHF10,ZNF84,NOA1,DCTD,PKM,KDM3A,PATL1,SF3A2,ADSS,EPRS,SERTAD2,ZNF777,ZFP92,QARS,DCK,ACLY,YY1,CDK2,RNF14,NRBP1,DNMT3A,RWDD1,ZBTB37,SUZ12,SF3B1,EIF3D,OLA1,ADPGK,SDE2,SDHA,TERF2IP,FLAD1,ZNF75D,KDM2A,UCHL5,TALDO1,MRM2,RFC3,ERF,TAOK1,SLBP,GAR1,POLG2,DHX57,CENPU,PRDM11,NSA2,VEZF1,MRPL55,GUCY1B1,FAAP100,TBL3,STAT1,PPA2,H2AFX,B4GALT3,PDCD11,ATMIN,CSNK1D,POLQ,POU3F2,NCOR2,TWNK,TCF3,BABAM1,MYNN,BLM,SPR,FOXO3,MAD2L2,GTF2F1,RBM17,RPL17,CRAT,COPS7B,UPF2,CREB1,CNOT6L,NCOA2,TSHZ1,ZFP64,RNASEH2C,TRIR,WDR18,RPL8,PARP4,ILF3,TBRG4,RPL27A,TSR2,POLR2A,ATP5MC3,HNRNPH3,TFDP1,KHSRP,NAXE,CPEB2,BYSL,DDX52,ADA2,IER2,PTMS,NOP2,ALKBH5,ZNF107,SIRT2,TAF6L,SLC29A1,SNRPD3,MAPK14,BECN1,SNAPC4,EDC3,MBD4,CYREN,THADA,EIF4A3,IMPAD1,DPYSL2,METTL14,PHTF1,KHDC4,ZBTB22,NDUFB9,KIF22,OGG1,ARID4A,ELOF1,COPS8,TDP1,RRM2,SOX4,DHX15,CHAF1A,UBTF,GEMIN5,PAF1,IARS2,PQBP1,COPS6,RPS26,RPS15,ZNF768,CIB1,MED13L,MEF2A,SRRT,NFATC3,ZNF449,ZNF335,BUD31,YBX1,ACAD8,N4BP2,ALDH9A1,ZNF189,VOPP1,TSTA3,CIC,ISG15,GNAS,NAP1L1,RBM25,CDCA5,TRMT10B,NUP62,ZFP90,RBBP4,HNRNPDL,NIPSNAP2,ZBTB24,MBD1,MMACHC,ASH1L,GNPNAT1,MPHOSPH8,CHERP,PLAGL2,NSD3,IRF3,CHD1,PAIP1,MEAF6,FARSA,ANKLE1,BABAM2,AKAP8,CHTOP,TMEM14C,HTRA2,RLIM,CGAS,ZNF500,NLN,BUD13,NDUFB1,EIF3G,RAD54B,ZNF317,DAP3,CHCHD1,AKNA,CBX4,MRPL42,EYA1,MRPS26,DBF4,KLF13,HDDC2,GART,CTNNBL1,PELO,BRD7,MRPL11,SAMD4B,GINS1,TELO2,GTF3C6,HMGN1,NASP,POLR3GL,MEN1,ATP5MF,ZNF407,SYMPK,SNRPA,TARS,HSPA1B,MAPK3,CNOT9,ATAD2,COX8A,ZRANB2,SRSF3,TATDN1,TYW1B |
| 3.862e-56 | -127.59 | GO_POLY_A_RNA_BINDING | MSigDB lists | GO_POLY_A_RNA_BINDING | 1095 | 367 | 17377 | 2626 |
PNISR,TXN,ADD1,MRPS15,YTHDF3,DHX8,UBE2I,EIF1B,MYEF2,RBM4,PARK7,PABPC4,RPL23A,PA2G4,NOL11,NSRP1,SRSF4,TRA2B,CISD2,LRRC59,FTSJ3,PCBP2,SRSF10,CDC5L,NOL12,SRP72,USO1,AATF,NOL8,NSUN2,MRPL43,MKI67,HNRNPF,DIDO1,SLC25A5,MAK16,EIF3A,CLNS1A,AHNAK,RBM47,RPS27A,LUC7L3,RPS14,MRPL27,MAP4,MYO18A,BTF3,RRS1,ZNF598,NMD3,CCDC59,ZMAT3,SMNDC1,HDAC2,ANXA11,DDX42,SSRP1,PPIB,PRPF38B,MRPL9,MAPRE1,EWSR1,GSPT2,DHX9,PARN,RAVER2,RPN1,DDX56,EIF2S2,MEX3C,RBM34,EFTUD2,ZNF326,MRPL40,CPSF4,MRPL21,PABPC1,LUC7L2,SRSF11,EIF5A,EIF3L,DDX28,RBM42,PRRC2A,NOA1,DHX29,RPS10,GTPBP4,C1orf35,USP10,RPS24,EXOSC9,BCLAF1,FAM133B,PLEC,SRSF5,FXR1,EIF4H,PATL1,ABCF1,SF3A2,MATR3,PHF6,HMGN2,AKAP1,XRCC5,CCDC86,RBMX,TCOF1,MRPL3,ZC3HAV1,CDKN2A,ZNF207,SARNP,NQO1,CAST,SF3B1,EIF3D,MYH9,SAFB2,GLRX3,CPNE3,KTN1,PAIP2,CRKL,UTP18,UCHL5,GRSF1,DUT,AQR,RBM12B,RBM15,SEC61B,CRNKL1,CIRBP,RNPS1,SLBP,NUSAP1,EDF1,GAR1,TRIM28,FKBP3,DHX57,SUPT16H,DDX17,NSA2,LSM6,SAFB,TBL3,RBMS1,SNRPG,PDCD11,PRPF4B,RPS2,SRSF6,MECP2,TRMT6,SECISBP2,HLA-A,RRP36,PNO1,GTF2F1,KRI1,ERH,RPL17,HUWE1,ARHGEF1,DCP1A,MRPL54,RPL19,NAP1L4,HNRNPM,STAU1,DDX24,ILF3,RPL8,TBRG4,LLPH,BMS1,RPL27A,DDX39A,MACF1,MARK2,PRDX1,POLR2A,UTP20,C1orf131,RPL32,MFAP1,HNRNPH3,LRPPRC,KHSRP,HMGB2,DUSP11,DDX5,CPEB2,PURA,BYSL,GPATCH4,DDX52,DDX47,HNRNPAB,NOP2,FLYWCH2,RBM8A,YTHDC2,ALKBH5,EBNA1BP2,SND1,SNRPD3,BRIX1,EDC3,KRR1,SF3B2,EIF4A3,GOT2,POP7,NOC2L,HADHB,RPF2,EIF5,MRPL32,CCAR1,SRPK2,FYTTD1,RPP25,SNRNP200,EXOSC6,SNRPB,EZR,SREK1,UTP3,PRKRA,LUC7L,DHX15,GEMIN5,UBTF,EIF4ENIF1,NIP7,CHD3,U2SURP,ATXN2L,KPNA2,MRPL13,FAM208A,RPS26,PSMC1,FUBP1,CCDC137,RPS15,ZCCHC9,PARP12,ZCCHC8,ZNF768,TIA1,RPL15,CDK13,THRAP3,SRRT,LYAR,SUB1,MBD2,YBX1,RBM3,ALDH18A1,NTPCR,SUGP2,RPL6,UTP15,RTF1,EIF4G2,SLTM,RBM38,RPL36,NAP1L1,SYNCRIP,RBM25,YWHAZ,SNRNP70,BCCIP,SART1,IMMT,SUCLG1,CHERP,MRPL39,MDH2,SUMO2,HNRNPUL2,TWF2,PCBP1,RPL11,CSDE1,HNRNPA2B1,FARSA,STRBP,NVL,CD3EAP,AKAP8,CS,TARDBP,CORO1A,CHTOP,STRAP,CSTF1,RPL29,RPL35,PPIE,PRPF3,BUD13,PEF1,MRPS14,RPS9,EIF3G,RPSA,USP36,EIF3H,SRSF1,SUGP1,MRPL2,DAP3,DUS3L,HNRNPR,CLK3,DHX16,CHCHD1,FAU,LTA4H,DNAJC2,UNK,CDC40,MRPL42,PDAP1,MRPS26,NKRF,ARF1,CDK11B,TFRC,FASTKD3,PPIG,RRBP1,ANP32A,DDX31,ERI3,FBL,MRPL11,MYO5A,RBM15B,PPAN,SAMD4B,YTHDC1,CSRP1,HMGN5,HELB,PSPC1,PRKDC,TUFM,API5,SNRPA,ZFR,DDX23,TPD52L2,UPF1,SEC23IP,ZC3H7B,ZRANB2,SRSF3,IFI16 |
| 4.113e-56 | -127.53 | PUJANA_BRCA1_PCC_NETWORK | MSigDB lists | PUJANA_BRCA1_PCC_NETWORK | 1554 | 467 | 17377 | 2626 |
FGFR1OP,MAX,H2AFZ,NUP188,TXN,ADAM10,CUL1,CCNB1,UBE2I,SLC20A1,PABPC4,RPL23A,KIFC1,ANKRD26,CDKN2C,PA2G4,RABGAP1L,ATP13A3,PDS5B,SUCLG2,TRA2B,NUP153,TAF5L,ECD,MOB1A,DNMT1,SRSF10,USP34,SRP72,PGAP2,ORAI2,NRAS,AATF,MKI67,HNRNPF,WDHD1,AURKB,SMC2,NUTF2,DIDO1,CCNF,MCM2,SLC25A5,RFC2,CBFB,MAK16,CLNS1A,STOML2,PRIM1,MAP3K4,WAS,SMAD2,RPS27A,TPP2,PTPN7,COX5A,UQCRH,ST3GAL2,BTF3,RRS1,TFDP2,SMNDC1,HDAC2,SSRP1,NXT2,HSPH1,NDUFV2,RECQL,MAPRE1,EWSR1,SEC61G,DHX9,RRM1,KIF23,TOP2B,CYCS,PSMD9,PARN,SPAG5,CNOT3,TFAP4,EIF2S2,EXOSC7,SMC3,MCM5,RBM34,ATIC,MSH2,ATP6V0A2,TNPO3,GEMIN4,CPSF4,PABPC1,PPP6R1,FDFT1,SRSF11,RBM42,RB1CC1,MYBL2,MFNG,KCTD20,USP10,RPS24,ARID1A,TOMM40,GOSR1,EIF4H,MATR3,MTR,CCT8,HMGN2,XRCC5,FAS,ADSS,EPRS,MTHFD2,POLR2J,DCK,RBMX,ACLY,CEBPG,PIAS2,TCOF1,YY1,CDK2,HEXA,MRPL3,ZC3HAV1,ZNF207,KARS,ATXN3,URB2,CAST,SF3B1,SUZ12,EIF3D,ACTR3,PTTG1,TPX2,STARD7,KLHL18,STMN1,EPM2A,CCNA2,SP100,UTP18,MTA1,DUT,MRPS27,RNASEH2A,ATF2,SAP30,ANKLE2,CCT2,SEC61B,RFC3,HMGN4,CDC123,VDAC2,E2F3,RNPS1,POLR2D,PFKFB3,SLBP,PKMYT1,CDC23,H2AFV,TRIM28,MAT2A,TAF2,KIF2A,NSA2,EIF3K,RAD51C,HSPA4,PEX5,CDC16,HINT1,ACYP1,LSM6,SAFB,TBL3,FTSJ1,H2AFX,SNRPG,USP13,PRPF4B,NDUFS1,TCF3,TKT,FAM76A,BRAP,SIKE1,BLM,PNO1,RPA2,ERH,PDCD10,RPL17,PPP1R8,AHSA1,ARHGEF1,GTSE1,RPL19,UPF2,NAP1L4,MTX2,UBE2M,MSH6,HNRNPM,TMX1,SMC4,LDHB,TK1,ILF3,JTB,LDHA,ADSL,BMS1,RPL27A,DDX39A,KIF11,PRDX1,RPA1,CBX3,UTP20,SLC19A1,POLE,PRDX3,PFDN4,MFAP1,TATDN2,PARG,DBI,TFDP1,KHSRP,HMGB2,DUSP11,IGBP1,TAF6,ESPL1,BYSL,DDX52,SRM,POLA2,CCNC,HNRNPAB,NOP2,SNX15,ENSA,DNAJC24,CSNK2A1,EBNA1BP2,KIF2C,SNRPD3,MAP1LC3B,MRPL19,GIT2,FANCI,SSR1,MBD4,ZNF804A,FANCL,PCNA,NUP210,EIF4A3,XRCC2,NOC2L,TCEA1,EIF5,OGG1,CARM1,TRIM14,PLK1,SNRNP200,DPM1,NCK1,VHL,SNRPB,RAD51AP1,MRPL12,SREK1,RRM2,PSMG1,ARHGDIB,CDC6,BRCA1,PITPNB,UTP3,IL12RB1,PRKRA,ODC1,STK17B,DHX15,CHAF1A,EPB41,RPL37,UBTF,HSPB11,E2F4,PPM1G,ATXN2L,IARS2,CRCP,BAZ1B,PRPF4,KPNA2,ACTB,CHEK2,POT1,FUBP1,UBE2D3,RMND5A,PPP1R2,TM9SF4,PHB2,NACA,CENPF,RPL15,CTCF,CDK13,CRLF3,SRRT,NUP205,RB1,SUB1,NFATC3,MBD2,PPIL2,BUD31,MEA1,CAPZA1,TIMELESS,CTR9,YBX1,AHCY,RBM3,KNTC1,GLE1,UBE3C,ABCC1,CREG1,RPL6,PSMA1,KRAS,NFATC2IP,IRF5,PSMC4,SDHB,NAP1L1,GALNT2,SYNCRIP,CDC27,PRPS2,COX7A2L,TBPL1,SLC16A1,NUP62,RUVBL2,RBBP4,CCNB2,PTDSS1,RNF114,ADNP2,ZBTB24,SMARCD1,TMEM106C,IMMT,RPLP2,CHERP,FOXM1,SUMO2,UCK2,PLAGL2,SMARCA4,ORC1,PCBP1,RPL11,HNRNPA2B1,OIP5,VAV1,FARSA,RRN3,MDM2,PSMA6,IARS,TNFAIP8,KIF14,PPP6C,EFCAB11,PDCD2,TARDBP,CORO1A,ABI1,HTRA2,PRPF19,POU2AF1,RPL35,POLR2G,PSMB7,DNAJC9,NUP155,VDAC1,TXNL4A,EIF3H,SRSF1,DAP3,HNRNPR,RBL1,DHX16,TIMM17A,PSMD3,ANP32E,XRCC3,MIF,DNAJC2,RAE1,PDAP1,CDT1,DBF4,HMGN3,GTF3A,NKRF,AP3S1,TFRC,HDDC2,SAC3D1,PTPN2,IRF4,GART,SLC1A4,PPIG,H2AFY,ANP32A,PTGES3,FBL,ORC3,GINS1,TGFB1,TXNL1,CSNK1G2,TELO2,ELOVL5,HMGN1,ADAM17,NASP,PRKDC,BTAF1,ZNF202,ABCF2,RCOR1,PCGF1,MEN1,API5,TARS,SNRPA,ZFR,SEC23IP,ZNF330,E2F1,ACADM,TAF12,SRSF3,IDH3B,UBE2C,GCSH,IFI16 |
| 1.029e-54 | -124.31 | macromolecule metabolic process | biological process | GO:0043170 | 7579 | 1517 | 17256 | 2622 |
ZBTB10,HEXB,TGOLN2,LACTB2,CCNL2,RBM4,ZNF275,FBXO22,EEF2K,RPL23A,USF1,RAD23B,DNM2,CRY2,ECD,RNF26,ZNRD1,TIPARP,ANKRD9,MGAT5,RHBDD2,FTSJ3,MRPL57,USP34,BAK1,ERCC1,ZNF559,NRAS,GABPA,EHMT1,HNRNPF,WDHD1,MIER2,DIDO1,MCM2,ARF4,GINS4,SMAD2,RAD18,RPS27A,MYO18A,OGT,RNASEL,KLHL42,SMAD1,CHPF2,ZNF75A,SMNDC1,SLC25A33,ZNF720,HIVEP3,CLSPN,GGA1,MUM1,TRIO,DHX9,KCTD17,EIF2AK4,PDCD7,PSMD9,APH1B,PARN,CDC73,ATG4A,TFAP4,PDXP,SMC3,RNFT1,FBXO7,EFTUD2,GEMIN4,MRPL21,CPSF4,NUP85,PABPC1,PHKG2,NSUN4,PPA1,LUC7L2,SRSF11,EIF3L,AGGF1,FOXK1,MAPKAPK3,MTA2,SF3B6,ERO1A,TYW1,GTPBP4,USP10,BCLAF1,MRPL16,ELK1,EIF4H,FNTA,KPNA1,ETS2,TYW5,WIPI2,ZNF830,CFAP20,MRPL3,NUP58,ALS2,TRIM41,KARS,PTTG1,INO80E,GLRX3,RCOR3,CPNE3,RBM23,FBXL6,ZNF420,MTA1,UBA5,GMEB1,NABP1,NSFL1C,INTS12,ZNF226,ZC3H3,RPRD1B,CGGBP1,CPNE1,ULK3,SEC61B,ERMP1,POLR2L,EID1,KAT7,CRNKL1,RPL38,E2F3,POLR2D,MEF2D,RAB1A,PPP2CA,LSM6,NSMCE2,CAMKMT,RNF38,DMWD,SNRPG,PPP5C,PITRM1,USP13,COMMD10,ZNF445,SRSF6,ZFP91,TRMT6,CCM2,HABP4,WDR5,NEXMIF,RRP36,NEIL2,TUT4,PPP1R3B,GOLM1,RPA2,ZBTB45,PSMD2,HUWE1,ZNF260,NAA50,LTN1,KANSL2,UBE3B,ST8SIA2,ZNF710,GTF2H2,FBXL19,RPL22L1,MED22,SPTAN1,DDX24,USP42,PICALM,UTP20,MAGT1,GPS2,PARG,DBI,AEN,CD81,PARP10,WDR45B,THAP5,TRIM11,YTHDC2,RBM8A,SND1,FANCI,PAPOLA,ZER1,KRR1,CREM,TET3,FANCL,RAB8A,NUP210,GLIS2,IL6ST,INTS1,POP7,NOC2L,EIF5,ASB6,RYBP,PLK1,RPP25,PTPN18,RBX1,APH1A,RAD51AP1,SNRPB,CDC6,UBE2V1,PBRM1,EAF2,UTP3,KRTCAP2,LUC7L,USP21,ALG3,TRIM4,CHD3,ZNF367,E2F4,ARRDC1,ADAM9,PRPF4,KPNA2,DVL1,CLN3,BEND6,FAM208A,NGLY1,POT1,ZNF564,FUBP1,RMND5A,CTU2,ZCCHC9,PHB2,CENPF,LAMTOR3,SDC2,CHCHD2,ADCK5,CDK13,RAB6A,CNOT11,ARID1B,C1GALT1,SUB1,MLX,UBE2Q2,CCP110,MBD2,SSBP3,XPA,ZNF746,CTR9,RBM3,ICE2,GLE1,MRPL48,LRSAM1,DCAF8,LDB1,MAP4K3,ZNF761,METTL22,ARMC8,STYXL1,RBM38,NMT2,IRF5,RXRB,RPL36,PAXX,MBIP,GALNT2,ZDHHC7,DTD1,RUVBL2,ECPAS,BCCIP,USP7,SART1,GLT8D1,TRAF7,RPLP2,ARID2,LAGE3,ZNF416,RRAGC,LYN,PCBP1,ZNF121,MRPL50,NRF1,PSMA6,ZNF473,KMT5C,BRPF3,ZNF302,ABRAXAS2,PIN1,PPME1,RPAP1,TARDBP,LMAN1,TOP1MT,AHCYL1,STRAP,SPIDR,CTDSP2,SPSB3,ZNF583,PRPF19,SNX25,PPIF,KDM3B,MND1,BIRC3,POLR2G,ZNF780B,PPT1,RAB7A,PPIE,NUP155,DCLRE1C,MRPS14,RHBDF2,EIF3H,SUGP1,IDE,DHX16,RBL1,UBXN2B,FASTK,STK38,UHRF2,CHMP4B,XRCC3,H3F3A,CHID1,SMAD4,RAD51D,SLC30A9,NIFK,MCM10,MTERF1,KLHL21,AGO2,TMX3,CDCA8,GTF3A,CDK11B,PAGR1,SCYL2,DNAJB9,HERC3,GTPBP3,CTSS,POLR1B,ORC3,RNF5,RBM15B,YTHDC1,RHOA,RPRD1A,HMGN5,PRKDC,TUFM,TOP3A,RANGAP1,PCGF1,DDX23,PDCD6,NEK1,L3MBTL3,NEIL3,CTBS,BBX,E2F1,USP20,RBPJ,TAF12,NR2F2,HIPK3,IFI16,TXN,NUP188,MAX,PDCD6IP,GXYLT1,ADAM10,PRKCSH,CXXC1,CUL1,USP39,GYG1,UBE2I,MYEF2,PARK7,ASPHD2,PA2G4,NOL11,FIZ1,ZNF200,TRA2B,FBXW2,AP2B1,TAF5L,MARCH2,ZNF800,CDC5L,SRSF10,ZNF524,KLF10,NSUN2,LACTB,USP22,CBFB,RFC2,CLNS1A,EIF3A,PRIM1,DOT1L,IWS1,MAP3K4,HHEX,MKNK1,BRD2,RPS14,TPP2,LUC7L3,MRPL27,BTF3,PTPDC1,SLF1,CCDC59,B4GALT2,PTOV1,PRPF38B,RECQL,EWSR1,DHPS,POLR2K,GSPT2,PRKAA1,RRM1,TATDN3,B4GALT1,CYCS,SUPT7L,PRPF39,ZNF79,ZNF518A,PSEN1,TMEM165,VPS25,YY1AP1,CNOT3,NPLOC4,WDR48,RPN1,LHX8,EXOSC7,KLHL5,ZNRF2,PPP4R1,MSH2,TPST1,DAPK1,PIGG,FBXL7,MRPL40,MRM3,APOL1,SOCS5,EIF5A,PIGT,PRIM2,CPQ,ELL2,COQ8A,MFNG,USF3,ZNF574,RPS24,EXOSC9,ARID1A,ADRB2,MAP2K2,TWISTNB,PHF6,XRCC5,DERL1,CAT,GOLGA2,EPOP,RBMX,MED15,PIAS2,USP32,CEBPG,ZNF511,NDC1,ATXN3,TP53RK,RAB11B,RAF1,C2orf49,SPINDOC,CCNA2,SIAH1,MTMR4,LPIN2,SOCS6,MRPS27,TTC3,RNASEH2A,AQR,ILKAP,CDK12,CFL1,SAP30,BRD4,DRAP1,ELP4,EDF1,PKMYT1,ASB13,ERC1,SERP1,TRIM28,SUPT16H,AMZ2,EIF3K,ANKZF1,ZNF282,RAD51C,HINT1,DDOST,DGCR8,SAFB,FTSJ1,ATF6,BEND3,XRCC4,EYA2,ADAM23,PRPF4B,DEPDC1,B4GALT5,MANBA,MECP2,CBLL1,ARGLU1,SECISBP2,POFUT1,HMG20A,WWP2,RFWD3,CCNK,DNAJC8,ELP5,FUT8,PTPN11,AXIN2,MRPL54,FEM1B,RPL19,CARF,CITED2,MSH6,KAT2A,LONRF3,RFXANK,FBXO9,BMS1,OTUD3,ARSK,GUF1,COMMD4,KLF6,SPPL2B,FADD,SH3GLB1,CBX3,RPL32,ZHX1,PPP1R11,DUSP11,DDX5,WDR62,WDR91,TAF6,ESPL1,PURA,DDB1,RORB,POLA2,CCNC,ZNF76,PIGM,KMT2E,PHRF1,UBE2Q1,PTP4A3,COMMD5,MRPL19,ZNF696,SF3B2,PCYOX1L,CDC42,JAZF1,RPF2,GPATCH1,TCEA1,SLC35C2,CARM1,SRPK2,DEAF1,LARS,SNRNP200,NCK1,LAP3,VHL,RIOX2,SREK1,SUMF2,KMT2C,ASF1B,RPL37,MAN2A2,BRWD1,U2SURP,PPM1G,CRCP,CAB39,BAZ1B,STK11,ZNF268,CHEK2,CLU,VPS4A,MRPL13,DCAF5,CAPN1,UBE2D3,NSMCE4A,PPP1R2,PPP1R12A,ZCCHC8,GORASP1,UBXN1,NACA,PCSK7,RPL15,PM20D2,THRAP3,XPNPEP3,TTF1,NUP205,PRPF18,LYAR,DTL,MED10,PYURF,TENM3,ZRANB1,CSNK1G3,POLR2I,ERLIN1,SUGP2,RPL6,EIF2A,SYVN1,VKORC1,SLTM,DAPK3,MASTL,KLHL15,NFIL3,SIAH2,FN3KRP,CTSA,SNRNP70,APOL2,TSEN15,ADNP2,TCF12,PRKAB1,MDH2,PMS2,SMARCA4,ORC1,EXT2,MXD1,USP5,HNRNPA2B1,SAP130,RRN3,UBXN2A,IARS,CD3EAP,KIF14,EXOSC1,PPP6C,UTP4,ZNF770,CSTF1,CHP1,POU2AF1,NXT1,PGGT1B,RNF25,METTL2A,SMU1,PCGF6,ATXN1,LSM8,OGDH,EDEM2,TOLLIP,MBD3,FANCE,RPS9,DUS3L,HNRNPR,STAT6,ARNTL,FKBP5,BRD9,MAPK1,ABCA1,CWC25,PDF,NAT14,DNAJC2,TRIP12,ZNF316,SHPRH,RAE1,SCYL1,NUP54,PAWR,MXD4,DCUN1D4,GFM2,SPPL2A,FASTKD3,FGFR3,GRK2,KLHL20,KMT5A,PPIG,RRBP1,NABP2,DUS2,ANP32A,FBL,ERI3,STAT3,SLC35A1,B3GALT6,TGFB1,PPP1R9B,DCAF6,HEMK1,HELB,PSPC1,MIER1,RFFL,RCOR1,PRMT2,CDK11A,TFEB,MTMR3,CTSL,UPF1,ZC3H7B,DTX4,KMT2B,ZMIZ1,PLOD3,HRAS,SLF2,TERF1,FGFR1OP,ADD1,KDM4A,MRPS15,MAP3K7CL,PIGQ,XIAP,DHX8,EDRF1,PABPC4,CDK5,PSMD1,CIPC,NEK6,NSRP1,SRSF4,PDS5B,FNIP2,NUP153,SENP1,PCBP2,PGAP2,PLK3,ZNF672,TMEM115,MRPL43,TOPORS,DCUN1D5,ICMT,STOML2,BRMS1,ZNF689,AXIN1,LIMK1,ATE1,VIPAS39,ST3GAL2,SMG9,FBXL3,TFDP2,E2F2,LONP2,AAAS,DDX42,SSRP1,MRPL9,MRPS2,TOP2B,EZH1,ZNRF3,MCTS1,RAVER2,DDRGK1,GNS,DDX56,EIF2S2,INTS7,MCM5,ZNF326,RTCB,FOXN2,CARS2,UBE2QL1,NAGPA,ETV3,RB1CC1,DHX29,ZMYND11,MAN1B1,TEX10,MYBL2,RPS10,ARMT1,SRSF5,CBFA2T2,MPG,ABCF1,PTPRF,POLR2J,DUSP3,CSK,SETD3,TEX30,PTAR1,CNOT6,HEXA,SGF29,RNF139,EGLN1,ZNF296,SARNP,ABCA3,TRERF1,IVNS1ABP,UBR2,CHD1L,RMI2,WDTC1,MYH9,CREBL2,RXYLT1,EFL1,ZNF267,SAFB2,PRKACA,TCF19,STAM,APP,KTN1,ANKIB1,PRKD3,SP100,ZKSCAN1,UTP18,DUT,GRSF1,DDA1,NUP107,ANAPC7,MAVS,RNF19A,ATF2,RBM15,CLN6,RNF169,INTS13,MAP4K4,RNPS1,WBP2,NDUFA7,FKBP3,DDX17,TAF2,CHCHD3,PEX5,CDC16,NT5C3B,HIPK2,RPLP1,RBMS1,FUS,GEN1,ZBTB11,LRP8,ZNF786,RPS2,TRAK1,JMJD6,UBE4A,ETS1,ZNF92,PNO1,KRI1,FBXO3,CAPN2,SUV39H2,GATC,PPP1R8,PRDM4,DCP1A,GTSE1,GEMIN6,TTLL12,HNRNPM,LYPLA2,PDPK1,PPP3CA,TK1,TNFAIP3,POLK,ZNF512,MRPS10,DDX39A,RPA1,ZNF180,ZNF862,KEAP1,POLE,TATDN2,PITX1,MAPK6,CAPN7,LRPPRC,PML,HMGB2,USF2,ANAPC4,FAF1,SNAPIN,DDX47,THOC1,AGRN,GPBP1L1,PPP1R15B,CSNK2A1,EBNA1BP2,BIRC2,LIN9,ABL2,PCNA,ZNF639,ETV6,TRMU,XRCC2,MCMBP,MYBL1,MRPL32,CCAR1,ABCC5,PTPRK,CDC37,SP3,METTL1,EXOSC6,BAZ2A,HARS,TLK1,MRPL12,GMFB,EZR,BRCA1,PRKRA,TONSL,NAGLU,SOCS4,QRSL1,ACTB,OSGEPL1,ZNF45,NAA60,GEMIN7,SEPHS2,TMUB1,CTCF,PPP3CB,B4GALT4,RLF,ASXL2,SNRNP25,RB1,NUS1,MED8,CMTR2,PPIL2,TIMELESS,MDFIC,MAML1,PREB,UTP15,KRAS,RTF1,EIF2AK1,UBE4B,NFATC2IP,LY6E,EIF4G2,ZDHHC3,ZNF174,PSMC4,SYNCRIP,PALB2,CDC27,TBPL1,PRMT7,RNF114,KCTD7,CYLD,UGP2,FOXM1,MRPL39,XAB2,DYNLL1,SUMO2,DUSP22,RPAIN,COMMD8,RPL11,RAD23A,SEC11A,CSDE1,PDK2,ZBTB21,MDM2,DUS4L,MRPL34,MINPP1,SAP30L,DVL2,RPL29,RPL35,PSMA8,BTG2,MTMR6,NFATC2,PRPF3,KDM1B,TXNL4A,USP36,RPSA,SRSF1,DNAJC10,MRPL2,CLK3,ZNF700,MAFK,PSMD3,ZNF436,DNAJC17,NCOA1,LTA4H,AP2S1,USP53,ZC3HC1,INTS2,CTDP1,CDC40,RRP15,CDT1,ARID5A,SMC6,NKRF,SUMF1,GGA2,CSNK1A1,RMI1,TFRC,WRNIP1,PTPN2,IRF4,CWC27,SS18L1,DDX31,PTGES3,CAMK2G,CNTN5,ZNF202,ZMYM5,PPWD1,FBXO41,GOLGA7,BIRC5,TFE3,CDCA7L,SPCS3,RPS6KC1,UBE2C,GCSH,ZNF496,ZDHHC8,NHLRC3,CCNB1,EIF1B,COMMD6,POLR3K,UTP25,SNUPN,PARPBP,RNASEK,CDC25B,MAST2,DNMT1,SEH1L,AKT2,PBK,NOL8,ELOA,MRNIP,DDX20,GALNT7,AURKB,CCNF,MCFD2,MAK16,RBM47,STT3A,PSMD8,WDR4,EIF2D,PTPN7,ITGB1,RRS1,ARRB2,ZNF598,HDAC2,DDX58,WSB2,PPIB,LIME1,GMFG,CHTF18,MAN2B1,NOTCH2,PMF1,METTL3,JMY,CFLAR,FKBP1A,RNF121,KLF16,HDAC7,DAD1,RNF135,EEF1D,TERF2,MORC3,PHF10,DDX28,ZNF84,NOA1,CYFIP2,KDM3A,PATL1,SF3A2,PSMB3,EPRS,ZNF777,SERTAD2,ZFP92,QARS,CSNK1G1,PPP3R1,DCAF11,VCPIP1,YY1,MAP3K5,RNF14,CDK2,NRBP1,ZC3HAV1,DNMT3A,RWDD1,ZBTB37,RPS6KA1,SF3B1,SUZ12,EIF3D,RAC1,KLHL18,SDE2,TERF2IP,CRKL,APLP2,ZNF75D,SHC1,KDM2A,UCHL5,NAA35,MRM2,RFC3,ERF,TAOK1,CUL3,SLBP,KIAA1586,CDC23,POLG2,GAR1,PSMB9,CENPU,DHX57,PRDM11,SOCS7,NSA2,VEZF1,PPP2R5A,MRPL55,JAK1,TBL3,FAAP100,STAT1,SEL1L,PPA2,H2AFX,TRIM32,B4GALT3,PDCD11,ATMIN,CSNK1D,POLQ,OTUD5,POU3F2,NCOR2,TWNK,TCF3,BABAM1,CDCA3,BRAP,MYNN,SDF2L1,BLM,RAB11A,FOXO3,MAD2L2,GTF2F1,RBM17,RPL17,PTEN,COPS7B,UPF2,OSTC,CREB1,MAP3K14,CNOT6L,UBE2M,NCOA2,TSHZ1,ZFP64,RNASEH2C,NEK7,TRIR,WDR18,PARP4,ILF3,RPL8,TBRG4,ANAPC2,RHOT1,RPL27A,MARK2,TSR2,POLR2A,FBXO21,NUCB1,SGSH,HGS,TTLL4,PRDX3,HNRNPH3,TFDP1,KHSRP,CPEB2,BYSL,DDX52,MIB2,ADA2,PTMS,IER2,UBE2E2,NOP2,DCAF15,NF1,ALKBH5,MOGS,DNAJC24,ZNF107,UBE2Z,SIRT2,AGFG1,TAF6L,UBQLN2,SNRPD3,FKBP2,USP48,BECN1,MAPK14,SNAPC4,RNF103,EDC3,UBLCP1,MBD4,CYREN,THADA,EIF4A3,ATG3,IMPAD1,METTL14,PHTF1,SRI,KHDC4,KIF22,ZBTB22,JOSD1,NFU1,OGG1,ARID4A,FGFR1OP2,TIMM50,ELOF1,COPS8,FYTTD1,TDP1,TRIM8,DPM1,RRM2,WDR82,SOX4,STK17B,DHX15,CHAF1A,GEMIN5,UBTF,PAF1,UEVLD,IARS2,PQBP1,ROCK1,GALNT10,COPS6,RPS26,PSMC1,RPS15,PIGN,ZNF768,UFC1,CIB1,MED13L,MEF2A,SRRT,RHBDD1,NFATC3,ZNF449,ZNF335,BUD31,BCL2,YBX1,ACAD8,UBE3C,N4BP2,ZNF189,VOPP1,CIC,PSMA1,ISG15,CAND1,GNAS,NAP1L1,RBM25,CDCA5,NUP62,TRMT10B,ZFP90,NAA20,RBBP4,HNRNPDL,ZBTB24,MBD1,TOMM20,ASH1L,MPHOSPH8,CHERP,WDYHV1,PLAGL2,NSD3,IRF3,CHD1,PAIP1,MEAF6,FARSA,ANKLE1,BABAM2,AKAP8,PARL,RPN2,CHTOP,PDIA6,ABI1,SCYL3,HTRA2,RLIM,ZNF500,PSMB7,NLN,BUD13,PEF1,EIF3G,BTBD1,RAD54B,ZNF317,DAP3,TAB2,CHCHD1,CANT1,USP11,AKNA,SMURF1,PPP2R2D,TSPAN5,CBX4,SH2D3A,MRPL42,CASP6,EYA1,SRGN,MRPS26,DBF4,KLF13,MAN1A1,CTNNBL1,PELO,TANK,BRD7,MRPL11,SAMD4B,GINS1,ZDHHC18,CSNK1G2,TELO2,GTF3C6,ADAM17,HMGN1,NASP,PRKAR1B,POLR3GL,WDR81,MEN1,ZNF407,SYMPK,SNRPA,TARS,MAPK3,HSPA1B,CNOT9,ATAD2,PLAA,KBTBD7,ZRANB2,MBD6,SRSF3,PREPL,TATDN1,TYW1B |
| 1.542e-52 | -119.30 | nucleobase-containing compound metabolic process | biological process | GO:0006139 | 4513 | 1012 | 17256 | 2622 |
ZBTB10,KDM4A,DHX8,LACTB2,CCNL2,EDRF1,RBM4,ZNF275,PABPC4,RPL23A,USF1,CIPC,NSRP1,RAD23B,SRSF4,PDS5B,UPRT,CRY2,ECD,ZNRD1,FTSJ3,KCNAB2,PCBP2,ZNF672,ERCC1,ZNF559,GABPA,EHMT1,HNRNPF,WDHD1,MIER2,TOPORS,DIDO1,MCM2,GINS4,STOML2,BRMS1,SMAD2,RAD18,RPS27A,ZNF689,MYO18A,COX5A,VIPAS39,RNASEL,SMG9,TFDP2,SMAD1,E2F2,ZNF75A,PFKP,SMNDC1,SLC25A33,DDX42,SSRP1,HIVEP3,NDUFV2,CLSPN,MUM1,DHX9,RAB23,TOP2B,EZH1,PDCD7,PARN,CDC73,MCTS1,RAVER2,TFAP4,DDX56,SMC3,INTS7,MCM5,EFTUD2,ZNF326,RTCB,FOXN2,GEMIN4,CPSF4,PABPC1,NSUN4,PPA1,LUC7L2,CARS2,SRSF11,AGGF1,ETV3,FOXK1,RB1CC1,DHX29,ZMYND11,MTA2,SF3B6,TEX10,TYW1,GTPBP4,RPS10,MYBL2,USP10,BCLAF1,SRSF5,CBFA2T2,MPG,ELK1,KPNA1,POLR2J,ETS2,SETD3,TYW5,MDH1,CNOT6,ZNF830,SGF29,ZNF296,KARS,SARNP,TRERF1,IVNS1ABP,UBR2,CHD1L,PTTG1,RMI2,CREBL2,ZNF267,SLC35B2,INO80E,EFL1,SAFB2,PRKACA,RCOR3,TCF19,APP,RBM23,ZNF420,SP100,UTP18,ZKSCAN1,MTA1,GRSF1,DUT,GMEB1,NABP1,INTS12,ZNF226,ATF2,RBM15,GPD1L,ZC3H3,RPRD1B,CGGBP1,PDCL3,ADCY7,ENPP4,CPNE1,POLR2L,EID1,KAT7,INTS13,CRNKL1,WBP2,RPL38,POLR2D,RNPS1,E2F3,ATP6V0A1,NDUFA7,MEF2D,TAZ,DDX17,TAF2,PPP2CA,CHCHD3,LSM6,NSMCE2,HIPK2,NT5C3B,RPLP1,RBMS1,FUS,SNRPG,PPP5C,GEN1,ZBTB11,COMMD10,GALK1,ZNF786,RPS2,ZNF445,SRSF6,TRMT6,HABP4,JMJD6,ABHD14B,ATP5F1B,WDR5,ETS1,NEXMIF,RRP36,PNO1,ZNF92,NEIL2,TUT4,KRI1,RPA2,ZBTB45,ERH,GATC,SUV39H2,NDUFB4,HUWE1,PPP1R8,PRDM4,ZNF260,DCP1A,GEMIN6,ZNF710,GTF2H2,HNRNPM,MED22,LDHB,PDPK1,TK1,GUK1,DDX24,POLK,ZNF512,LDHA,DDX39A,PDE3B,RPA1,UTP20,ZNF862,ZNF180,KEAP1,POLE,TATDN2,PARG,PITX1,LRPPRC,PML,AEN,HMGB2,PARP10,USF2,THAP5,COX15,DDX47,THOC1,GPBP1L1,GNPDA1,YTHDC2,RBM8A,CSNK2A1,EBNA1BP2,SND1,BIRC2,FANCI,PAPOLA,CREM,KRR1,LIN9,FANCL,TET3,PCNA,GLIS2,ZNF639,INTS1,ETV6,TRMU,XRCC2,POP7,NOC2L,PPCDC,MCMBP,MYBL1,CCAR1,RYBP,SP3,METTL1,RPP25,EXOSC6,RBX1,HARS,BAZ2A,RAD51AP1,SNRPB,MRPL12,CDC6,UBE2V1,PBRM1,EAF2,UTP3,BRCA1,PRKRA,LUC7L,USP21,TONSL,CHD3,ZNF367,E2F4,QRSL1,PRPF4,KPNA2,DVL1,DHFR2,OSGEPL1,ZNF45,BEND6,FAM208A,NUDT11,POT1,GEMIN7,ZNF564,FUBP1,SEPHS2,CTU2,ZCCHC9,PHB2,CENPF,CTCF,CHCHD2,COX4I1,CDK13,RLF,ASXL2,CNOT11,ARID1B,SNRNP25,SUB1,RB1,MLX,MED8,MBD2,CMTR2,SSBP3,XPA,ZNF746,CTR9,TIMELESS,MDFIC,AHCY,RBM3,ICE2,MAML1,PREB,LDB1,AMD1,UTP15,RTF1,ZNF761,RBM38,IRF5,ZNF174,RXRB,RPL36,PAXX,MBIP,SYNCRIP,PALB2,PRPS2,COX7A2L,TBPL1,PRMT7,DTD1,RUVBL2,ATP5F1A,BCCIP,USP7,SART1,NDUFA5,TRAF7,RPLP2,UGP2,SUCLG1,ARID2,FOXM1,MRPL39,DYNLL1,XAB2,SUMO2,LAGE3,ZNF416,RRAGC,ATP6V1B2,PCBP1,COMMD8,RPAIN,ZNF121,RAD23A,RPL11,CSDE1,ZBTB21,NRF1,ZNF473,KMT5C,DUS4L,ZNF302,RPAP1,TARDBP,TOP1MT,AHCYL1,STRAP,SAP30L,SPIDR,ZNF583,DVL2,PRPF19,KDM3B,MND1,RPL29,RPL35,POLR2G,ZNF780B,BTG2,PPIE,NFATC2,DCLRE1C,PRPF3,KDM1B,TXNL4A,RPSA,SRSF1,SUGP1,DHX16,ZNF700,RBL1,MAFK,NDUFA11,ZNF436,UHRF2,DNAJC17,XRCC3,NCOA1,SMAD4,RAD51D,INTS2,SLC30A9,CTDP1,NADSYN1,NIFK,MCM10,CDC40,MTERF1,RRP15,CDT1,GNE,AGO2,ARID5A,SMC6,GTF3A,NKRF,PAGR1,RMI1,WRNIP1,GTPBP3,IRF4,NDUFV1,CWC27,DDX31,SS18L1,PTGES3,POLR1B,ORC3,RNLS,RBM15B,YTHDC1,RPRD1A,RHOA,HMGN5,PRKDC,ZNF202,ZMYM5,TOP3A,PPWD1,PCGF1,DDX23,BIRC5,L3MBTL3,NEIL3,TFE3,CDCA7L,BBX,E2F1,IMPDH1,RBPJ,TAF12,NR2F2,PGAM1,HIPK3,IFI16,TXN,ZNF496,MAX,PPCS,NDUFB6,CXXC1,USP39,NANS,CCNB1,UBE2I,COMMD6,POLR3K,MYEF2,PARK7,UTP25,PA2G4,SNUPN,NOL11,PARPBP,FIZ1,RNASEK,ZNF200,TRA2B,TAF5L,SLC26A2,DNMT1,ZNF800,CDC5L,SRSF10,ZNF524,KLF10,NOL8,NSUN2,ELOA,MRNIP,DDX20,USP22,AMDHD2,CBFB,RFC2,MAK16,CLNS1A,PRIM1,DOT1L,IWS1,HHEX,RBM47,BRD2,RPS14,LUC7L3,WDR4,DHTKD1,UQCRH,BTF3,RRS1,ARRB2,SLF1,CCDC59,HDAC2,PTOV1,PRPF38B,RECQL,COX5B,EWSR1,LIME1,POLR2K,CHTF18,PRKAA1,GSPT2,RRM1,TATDN3,NDUFA4,CYCS,PMF1,NOTCH2,SUPT7L,PRPF39,ZNF79,ZNF518A,METTL3,VPS25,NDUFS7,YY1AP1,NPLOC4,CNOT3,JMY,WDR48,NDUFS4,LHX8,EXOSC7,KLF16,HDAC7,ATIC,CTPS1,MSH2,TPST1,ATP6V0A2,CYC1,MRM3,EEF1D,TERF2,PHF10,DDX28,ZNF84,PRIM2,ELL2,ZNF574,RPS24,DCTD,EXOSC9,ARID1A,PKM,KDM3A,PATL1,SF3A2,TWISTNB,PHF6,XRCC5,ADSS,EPRS,ZNF777,SERTAD2,ZFP92,RBMX,QARS,DCK,MED15,ACLY,PIAS2,CEBPG,GPI,YY1,RNF14,CDK2,NRBP1,NUDT3,ZNF511,DNMT3A,ATXN3,TP53RK,ZBTB37,SF3B1,SUZ12,OLA1,ADPGK,C2orf49,SDHA,SDE2,TERF2IP,SPINDOC,FLAD1,ZNF75D,KDM2A,UCHL5,LPIN2,ADCY9,RNASEH2A,AQR,TALDO1,CDK12,MRM2,SAP30,BRD4,RFC3,ERF,DRAP1,TAOK1,SLBP,ELP4,EDF1,POLG2,GAR1,TRIM28,CENPU,DHX57,PRDM11,SUPT16H,NSA2,VEZF1,ZNF282,RAD51C,HINT1,DGCR8,SAFB,TBL3,FAAP100,GUCY1B1,H2AFX,STAT1,FTSJ1,PPA2,ATF6,BEND3,PDCD11,XRCC4,EYA2,CSNK1D,ATMIN,POLQ,PRPF4B,POU3F2,NCOR2,NDUFS1,DEPDC1,TWNK,MECP2,TCF3,BABAM1,TKT,ARGLU1,MYNN,BLM,HMG20A,FOXO3,MAD2L2,WWP2,GTF2F1,RBM17,RFWD3,CCNK,DNAJC8,NDUFA2,RPL17,ELP5,FUT8,AXIN2,RPL19,UPF2,COPS7B,CARF,CITED2,CNOT6L,CREB1,NDUFA3,MSH6,NCOA2,TSHZ1,ZFP64,KAT2A,RNASEH2C,TRIR,WDR18,ILF3,PARP4,RPL8,RFXANK,ADSL,TBRG4,BMS1,KCNQ1,RPL27A,KLF6,COMMD4,TSR2,POLR2A,CBX3,RPL32,ATP5MC3,ZHX1,HNRNPH3,TFDP1,KHSRP,NAXE,DUSP11,DDX5,NDUFS5,WDR62,TAF6,PURA,DDB1,BYSL,DDX52,RORB,ADA2,POLA2,CCNC,ZNF76,PTMS,IER2,NOP2,KMT2E,UQCR10,PHRF1,ALKBH5,ZNF107,SLC29A1,TAF6L,SIRT2,SNRPD3,COMMD5,MAPK14,ATP5PF,SNAPC4,ZNF696,EDC3,SF3B2,MBD4,CYREN,EIF4A3,THADA,METTL14,IMPAD1,JAZF1,DPYSL2,PHTF1,RPF2,GPATCH1,KHDC4,KIF22,NDUFB9,ZBTB22,TCEA1,OGG1,ARID4A,CARM1,SRPK2,ELOF1,COPS8,TDP1,DEAF1,LARS,SNRNP200,RIOX2,SREK1,RRM2,KMT2C,SOX4,PRPSAP1,MPC1,ASF1B,DHX15,CHAF1A,RPL37,PAF1,GEMIN5,UBTF,BRWD1,U2SURP,PQBP1,IARS2,CRCP,BAZ1B,ZNF268,CHEK2,COPS6,RPS26,UBE2D3,RPS15,NSMCE4A,ZCCHC8,ZNF768,NACA,CIB1,MED13L,RPL15,MEF2A,THRAP3,TTF1,SRRT,PRPF18,LYAR,DTL,NFATC3,ZNF449,MED10,ZNF335,BUD31,YBX1,ACAD8,N4BP2,ZNF189,VOPP1,POLR2I,TSTA3,NUDT4,CIC,SUGP2,RPL6,SLTM,DAPK3,ISG15,GNAS,NAP1L1,RBM25,UAP1,NFIL3,CDCA5,TRMT10B,NUP62,DNPH1,ZFP90,RBBP4,SNRNP70,HNRNPDL,NIPSNAP2,TSEN15,ZBTB24,ADNP2,TCF12,MBD1,ASH1L,MPHOSPH8,GNPNAT1,CHERP,MDH2,PMS2,UCK2,SMARCA4,UCK1,PLAGL2,NSD3,ORC1,IRF3,CHD1,MEAF6,MXD1,PAIP1,HNRNPA2B1,SAP130,FARSA,RRN3,ANKLE1,BABAM2,IARS,CD3EAP,EXOSC1,AKAP8,CHTOP,UTP4,ZNF770,RLIM,CSTF1,POU2AF1,CGAS,ZNF500,METTL2A,SMU1,PCGF6,LSM8,ATXN1,OGDH,NDUFB1,BUD13,MBD3,FANCE,RPS9,PDHX,RAD54B,ZNF317,DUS3L,HNRNPR,STAT6,ARNTL,AKNA,MAPK1,BRD9,CBX4,CWC25,NAT14,DNAJC2,TRIP12,ZNF316,SHPRH,EYA1,SCYL1,DBF4,KLF13,PAWR,MXD4,HDDC2,GART,CTNNBL1,KMT5A,PPIG,PELO,DUS2,NABP2,BRD7,ANP32A,NDUFS8,ERI3,FBL,STAT3,AMPD2,TGFB1,SAMD4B,GINS1,TELO2,GTF3C6,PPP1R9B,HEMK1,HMGN1,NASP,PSPC1,HELB,MIER1,NADK2,RCOR1,POLR3GL,MEN1,ATP5MF,ZNF407,SYMPK,SNRPA,TARS,MAPK3,TFEB,HSPA1B,CNOT9,UPF1,ATAD2,ZC3H7B,COX8A,KMT2B,ACAT1,ZRANB2,SRSF3,TATDN1,ZMIZ1,SLF2,TERF1,TYW1B |
| 6.690e-51 | -115.53 | GO_RNA_BINDING | MSigDB lists | GO_RNA_BINDING | 1488 | 441 | 17377 | 2626 |
PNISR,TXN,ADD1,MRPS15,YTHDF3,DHX8,UBE2I,EIF1B,MYEF2,PARK7,RBM4,PABPC4,RPL23A,EEF2K,PA2G4,SNUPN,NOL11,NSRP1,SRSF4,TRA2B,CISD2,SMARCE1,LRRC59,DNMT1,FTSJ3,PCBP2,CDC5L,SRSF10,NOL12,SRP72,USO1,AATF,NOL8,NSUN2,MKI67,MRPL43,HNRNPF,DIDO1,SLC25A5,MAK16,EIF3A,CLNS1A,AHNAK,RBM47,RPS27A,RPS14,LUC7L3,EIF2D,MRPL27,MAP4,MYO18A,BTF3,RNASEL,RRS1,ZNF598,NMD3,ZMAT3,CCDC59,HDAC2,SMNDC1,PDCD4,ANXA11,SSRP1,DDX42,DDX58,PPIB,PRPF38B,MAPRE1,MRPL9,EWSR1,GSPT2,DHX9,EIF2AK4,PRPF39,PARN,METTL3,MCTS1,RAVER2,DDX56,RPN1,EIF2S2,EXOSC7,MEX3C,RBM34,EFTUD2,ZNF326,MRPL40,MRPL21,CPSF4,PABPC1,NSUN4,EEF1D,LUC7L2,MORC3,EIF5A,SRSF11,DDX28,EIF3L,RBM42,PRRC2A,NOA1,DHX29,RPS10,GTPBP4,RPS24,C1orf35,USP10,FAM133B,EXOSC9,BCLAF1,MRPL16,PLEC,SRSF5,FXR1,EIF4H,SF3A2,PATL1,MATR3,ABCF1,PHF6,XRCC5,AKAP1,HMGN2,EPRS,CCDC86,QARS,RBMX,TYW5,CNOT6,TCOF1,YY1,MRPL3,ZC3HAV1,CDKN2A,ZNF207,KARS,SARNP,NQO1,CAST,SF3B1,SUZ12,EIF3D,MYH9,SAFB2,GLRX3,KTN1,CPNE3,PAIP2,CRKL,RBM23,UTP18,UCHL5,DUT,GRSF1,RNASEH2A,AQR,RBM12B,RBM15,CDKN2AIP,SEC61B,RNPS1,CRNKL1,CIRBP,RPL38,POLR2D,SLBP,NUSAP1,EDF1,GAR1,FKBP3,TRIM28,DHX57,DDX17,SUPT16H,NSA2,EIF3K,DGCR8,LSM6,TBL3,SAFB,RPLP1,RBMS1,TRIM32,SNRPG,PPP5C,PDCD11,PRPF4B,RPS2,MECP2,SRSF6,TRMT6,JMJD6,SECISBP2,PNO1,HLA-A,RRP36,GTF2F1,JAKMIP1,RBM17,KRI1,ERH,RPL17,HUWE1,PPP1R8,ARHGEF1,DCP1A,MRPL54,UPF2,RPL19,NAP1L4,GTF2H2,HNRNPM,STAU1,DDX24,ILF3,RPL8,TBRG4,BMS1,LLPH,RPL27A,DDX39A,MACF1,MARK2,PRDX1,POLR2A,UTP20,C1orf131,RPL32,MFAP1,HNRNPH3,LRPPRC,KHSRP,HMGB2,DUSP11,DDX5,CPEB2,PURA,BYSL,GPATCH4,DDX52,DDX47,HNRNPAB,NOP2,THOC1,FLYWCH2,YTHDC2,RBM8A,ALKBH5,EBNA1BP2,AGFG1,SND1,SNRPD3,BRIX1,EDC3,KRR1,PAPOLA,SF3B2,EIF4A3,GOT2,METTL14,TRMU,POP7,NOC2L,HADHB,RPF2,EIF5,MRPL32,CCAR1,TIMM50,SRPK2,FYTTD1,METTL1,RPP25,EXOSC6,SNRNP200,BAZ2A,SNRPB,RAD51AP1,MRPL12,EZR,SREK1,BRCA1,UTP3,PRKRA,LUC7L,DHX15,GEMIN5,UBTF,RPL37,EIF4ENIF1,CHD3,NIP7,U2SURP,ATXN2L,PRPF4,KPNA2,FAM208A,MRPL13,PSMC1,RPS26,CCDC137,FUBP1,CTU2,RPS15,PARP12,ZCCHC9,ZCCHC8,ZNF768,TIA1,RPL15,CDK13,THRAP3,SRRT,LYAR,SUB1,MBD2,YBX1,RBM3,ALDH18A1,NTPCR,NUDT4,SUGP2,UTP15,RPL6,PSMA1,RTF1,EIF2A,EIF4G2,SLTM,RBM38,RPL36,NAP1L1,RBM25,SYNCRIP,YWHAZ,SNRNP70,BCCIP,SART1,IMMT,RPLP2,SUCLG1,CHERP,MRPL39,MDH2,HNRNPUL2,SUMO2,TWF2,PCBP1,PAIP1,RPL11,CSDE1,HNRNPA2B1,FARSA,PSMA6,STRBP,CD3EAP,NVL,AKAP8,EXOSC1,CS,TARDBP,CORO1A,CHTOP,AHCYL1,STRAP,CSTF1,RPL29,RPL35,POLR2G,PPIE,ATXN1,PRPF3,BUD13,PEF1,MRPS14,EIF3G,RPS9,RPSA,USP36,EIF3H,SRSF1,SUGP1,MRPL2,DAP3,DUS3L,CLK3,DHX16,HNRNPR,CHCHD1,FASTK,DNAJC17,FAU,LTA4H,CBX4,UNK,DNAJC2,MIF4GD,CDC40,MRPL42,EYA1,PDAP1,RAE1,MRPS26,NKRF,GTF3A,ARF1,CDK11B,GFM2,TFRC,FASTKD3,PPIG,RRBP1,ANP32A,DDX31,MRPL11,FBL,ERI3,MYO5A,RBM15B,SAMD4B,YTHDC1,PPAN,CSRP1,HMGN5,PRKDC,HELB,PSPC1,TUFM,API5,TARS,SNRPA,ZFR,DDX23,TPD52L2,SEC23IP,UPF1,ZC3H7B,IMPDH1,ZRANB2,SRSF3,IFI16 |
| 9.868e-51 | -115.14 | heterocycle metabolic process | biological process | GO:0046483 | 4689 | 1036 | 17256 | 2622 |
ZBTB10,LACTB2,CCNL2,RBM4,ZNF275,RPL23A,USF1,RAD23B,UPRT,CRY2,ECD,ZNRD1,FTSJ3,ERCC1,ZNF559,GABPA,EHMT1,HNRNPF,WDHD1,MIER2,DIDO1,MCM2,GINS4,SMAD2,RAD18,RPS27A,MYO18A,COX5A,RNASEL,SMAD1,ZNF75A,SMNDC1,SLC25A33,HIVEP3,CLSPN,MUM1,DHX9,RAB23,PDCD7,PARN,CDC73,TFAP4,PDXP,SMC3,EFTUD2,GEMIN4,CPSF4,PABPC1,NSUN4,PPA1,LUC7L2,SRSF11,AGGF1,FOXK1,MTA2,SF3B6,TYW1,GTPBP4,USP10,BCLAF1,ELK1,KPNA1,ETS2,TYW5,ZNF830,KARS,PTTG1,INO80E,SLC35B2,RCOR3,RBM23,ZNF420,MTA1,GMEB1,NABP1,INTS12,ZNF226,GPD1L,ZC3H3,RPRD1B,CGGBP1,PDCL3,CPNE1,POLR2L,EID1,KAT7,CRNKL1,RPL38,E2F3,POLR2D,MEF2D,PPP2CA,LSM6,NSMCE2,SNRPG,PPP5C,COMMD10,ZNF445,SRSF6,TRMT6,HABP4,ABHD14B,ATP5F1B,WDR5,NEXMIF,RRP36,NEIL2,TUT4,RPA2,ZBTB45,HUWE1,ZNF260,ZNF710,GTF2H2,MED22,DDX24,LDHA,UTP20,SLC19A1,PARG,AEN,PARP10,THAP5,YTHDC2,RBM8A,SND1,FANCI,PAPOLA,KRR1,CREM,TET3,FANCL,GLIS2,INTS1,POP7,NOC2L,RYBP,RPP25,RBX1,RAD51AP1,SNRPB,CDC6,UBE2V1,PBRM1,EAF2,UTP3,LUC7L,USP21,CHD3,ZNF367,E2F4,PRPF4,KPNA2,DVL1,BEND6,FAM208A,POT1,ZNF564,FUBP1,CTU2,ZCCHC9,PHB2,CENPF,CHCHD2,COX4I1,CDK13,CNOT11,RSAD1,ARID1B,SUB1,MLX,MBD2,SSBP3,XPA,ZNF746,CTR9,AHCY,RBM3,ICE2,LDB1,AMD1,ZNF761,RBM38,IRF5,RXRB,RPL36,PAXX,MBIP,COX7A2L,DTD1,RUVBL2,BCCIP,USP7,SART1,TRAF7,RPLP2,SUCLG1,ARID2,LAGE3,ZNF416,RRAGC,ATP6V1B2,PCBP1,ZNF121,NRF1,ZNF473,KMT5C,ZNF302,RPAP1,TARDBP,TOP1MT,AHCYL1,STRAP,SPIDR,ZNF583,PRPF19,KDM3B,MND1,POLR2G,ZNF780B,PPIE,DCLRE1C,SUGP1,DHX16,RBL1,UHRF2,XRCC3,SMAD4,RAD51D,SLC30A9,NADSYN1,NIFK,MCM10,MTERF1,AGO2,GTF3A,PAGR1,GTPBP3,POLR1B,ORC3,RNLS,RBM15B,YTHDC1,RHOA,RPRD1A,HMGN5,PRKDC,TOP3A,PCGF1,DDX23,L3MBTL3,NEIL3,BBX,E2F1,IMPDH1,RBPJ,TAF12,NR2F2,PGAM1,HIPK3,IFI16,TXN,MAX,CXXC1,USP39,NANS,UBE2I,OAT,MYEF2,PARK7,PA2G4,NOL11,FIZ1,ZNF200,TRA2B,TAF5L,SLC26A2,ZNF800,CDC5L,SRSF10,ZNF524,KLF10,NSUN2,USP22,CBFB,RFC2,CLNS1A,PRIM1,DOT1L,IWS1,HHEX,BRD2,RPS14,LUC7L3,BTF3,SLF1,CCDC59,PTOV1,PRPF38B,RECQL,COX5B,EWSR1,POLR2K,PRKAA1,GSPT2,RRM1,TATDN3,CYCS,SUPT7L,PRPF39,ZNF79,ZNF518A,VPS25,NDUFS7,YY1AP1,CNOT3,NPLOC4,WDR48,LHX8,EXOSC7,MSH2,TPST1,CYC1,MRM3,PRIM2,ELL2,ZNF574,RPS24,EXOSC9,ARID1A,MTR,TWISTNB,PHF6,XRCC5,MTHFD2,RBMX,MED15,PIAS2,CEBPG,GPI,NUDT3,ZNF511,ATXN3,TP53RK,UROD,C2orf49,CD320,SPINDOC,LPIN2,ADCY9,RNASEH2A,AQR,CDK12,SAP30,BRD4,DRAP1,ELP4,EDF1,TRIM28,SUPT16H,ZNF282,RAD51C,HINT1,DGCR8,SAFB,FTSJ1,ATF6,BEND3,XRCC4,EYA2,PRPF4B,NDUFS1,DEPDC1,MECP2,TKT,ARGLU1,HMG20A,WWP2,RFWD3,CCNK,DNAJC8,NDUFA2,ELP5,FUT8,AXIN2,RPL19,CARF,CITED2,NDUFA3,MSH6,KAT2A,RFXANK,ADSL,BMS1,KCNQ1,COMMD4,KLF6,CBX3,RPL32,ZHX1,DUSP11,DDX5,NDUFS5,WDR62,TAF6,PURA,DDB1,RORB,POLA2,CCNC,ZNF76,KMT2E,UQCR10,PHRF1,COMMD5,ATP5PF,ZNF696,SF3B2,JAZF1,RPF2,GPATCH1,TCEA1,CARMIL1,CARM1,SRPK2,DEAF1,LARS,SNRNP200,RIOX2,SREK1,KMT2C,PRPSAP1,MPC1,ASF1B,RPL37,BRWD1,U2SURP,CRCP,BAZ1B,ZNF268,CHEK2,UBE2D3,NSMCE4A,ZCCHC8,NACA,RPL15,PM20D2,THRAP3,TTF1,PRPF18,LYAR,DTL,MED10,ATP5IF1,POLR2I,NUDT4,SUGP2,RPL6,SLTM,DAPK3,UAP1,NFIL3,DNPH1,SNRNP70,TSEN15,ADNP2,TCF12,MDH2,UCK2,PMS2,SMARCA4,UCK1,ORC1,MXD1,HNRNPA2B1,SAP130,RRN3,IARS,CD3EAP,EXOSC1,UTP4,ZNF770,CSTF1,POU2AF1,METTL2A,SMU1,PCGF6,LSM8,ATXN1,OGDH,MBD3,FANCE,RPS9,PDHX,DUS3L,HNRNPR,STAT6,ARNTL,MAPK1,BRD9,CWC25,NAT14,DNAJC2,TRIP12,ZNF316,SHPRH,SCYL1,PAWR,MXD4,KMT5A,PPIG,DUS2,NABP2,ANP32A,NDUFS8,ERI3,FBL,STAT3,AMPD2,TGFB1,PPP1R9B,HEMK1,PSPC1,HELB,MIER1,NADK2,RCOR1,TFEB,UPF1,ZC3H7B,KMT2B,ACAT1,ZMIZ1,SLF2,TERF1,KDM4A,DHX8,EDRF1,PABPC4,CIPC,NSRP1,SRSF4,PDS5B,PCBP2,KCNAB2,ZNF672,TOPORS,STOML2,BRMS1,ZNF689,VIPAS39,SMG9,TFDP2,E2F2,PFKP,SSRP1,DDX42,NDUFV2,TOP2B,EZH1,RAVER2,MCTS1,DDX56,INTS7,MCM5,ZNF326,RTCB,FOXN2,CARS2,ETV3,RB1CC1,ZMYND11,DHX29,TEX10,MYBL2,RPS10,SRSF5,MPG,CBFA2T2,POLR2J,SETD3,CNOT6,MDH1,SGF29,ZNF296,SARNP,TRERF1,IVNS1ABP,UBR2,CHD1L,RMI2,CREBL2,EFL1,ZNF267,TCF19,PRKACA,SAFB2,APP,SP100,ZKSCAN1,UTP18,DUT,GRSF1,RBM15,ATF2,ADCY7,ENPP4,INTS13,RNPS1,WBP2,ATP6V0A1,NDUFA7,TAZ,DDX17,CHCHD3,TAF2,NT5C3B,HIPK2,RPLP1,RBMS1,FUS,PDXK,ZBTB11,GEN1,ZNF786,GALK1,RPS2,JMJD6,ETS1,ZNF92,PNO1,KRI1,ERH,SUV39H2,GATC,NDUFB4,PPP1R8,PRDM4,GEMIN6,DCP1A,HNRNPM,LDHB,PDPK1,TK1,GUK1,POLK,ZNF512,PDE3B,DDX39A,RPA1,ZNF862,ZNF180,KEAP1,POLE,TATDN2,PITX1,PML,LRPPRC,SLC25A19,HMGB2,USF2,COX15,DDX47,THOC1,GNPDA1,GPBP1L1,MCCC1,CSNK2A1,EBNA1BP2,BIRC2,LIN9,PCNA,ZNF639,XRCC2,TRMU,ETV6,PPCDC,MYBL1,MCMBP,CCAR1,SP3,METTL1,EXOSC6,BAZ2A,HARS,MRPL12,BRCA1,PRKRA,TONSL,QRSL1,DHFR2,ZNF45,OSGEPL1,NUDT11,GEMIN7,SEPHS2,CTCF,ASXL2,RLF,RB1,SNRNP25,MED8,CMTR2,TIMELESS,MDFIC,ALDH18A1,MAML1,ABCC1,PREB,UTP15,RTF1,EIF2AK1,ZNF174,PALB2,SYNCRIP,PRPS2,TBPL1,PRMT7,ATP5F1A,NDUFA5,UGP2,FOXM1,XAB2,DYNLL1,MRPL39,SUMO2,RPAIN,COMMD8,RPL11,RAD23A,CSDE1,ZBTB21,DUS4L,SAP30L,DVL2,RPL29,RPL35,BTG2,CPOX,NFATC2,PRPF3,KDM1B,TXNL4A,RPSA,SRSF1,ZNF700,MAFK,NDUFA11,DNAJC17,ZNF436,NCOA1,SLC25A39,INTS2,CTDP1,CDC40,RRP15,GNE,CDT1,ARID5A,SMC6,NKRF,RMI1,WRNIP1,IRF4,NDUFV1,CWC27,SS18L1,DDX31,PTGES3,ZNF202,ZMYM5,PPWD1,BIRC5,TFE3,CDCA7L,PPCS,ZNF496,NDUFB6,CCNB1,COMMD6,POLR3K,UTP25,SNUPN,RNASEK,PARPBP,DNMT1,NOL8,ELOA,DDX20,MRNIP,AMDHD2,MAK16,RBM47,WDR4,DHTKD1,UQCRH,RRS1,ARRB2,HDAC2,LIME1,MUT,CHTF18,NDUFA4,NOTCH2,PMF1,METTL3,JMY,NDUFS4,KLF16,ATIC,HDAC7,CTPS1,ATP6V0A2,EEF1D,TERF2,DDX28,PHF10,ZNF84,DCTD,PKM,KDM3A,SF3A2,PATL1,ADSS,EPRS,SERTAD2,ZNF777,ZFP92,DCK,QARS,ACLY,YY1,CDK2,RNF14,NRBP1,DNMT3A,SUZ12,SF3B1,ZBTB37,OLA1,ADPGK,SDE2,SDHA,FLAD1,TERF2IP,ZNF75D,KDM2A,UCHL5,TALDO1,MRM2,RFC3,ERF,TAOK1,SLBP,GAR1,POLG2,DHX57,CENPU,PRDM11,NSA2,VEZF1,GUCY1B1,FAAP100,TBL3,PPA2,STAT1,H2AFX,PDCD11,ATMIN,CSNK1D,POLQ,POU3F2,NCOR2,TWNK,BABAM1,TCF3,MYNN,BLM,SPR,FOXO3,MAD2L2,GTF2F1,RBM17,RPL17,COPS7B,UPF2,CREB1,CNOT6L,NCOA2,TSHZ1,ZFP64,RNASEH2C,TRIR,WDR18,RPL8,PARP4,ILF3,TBRG4,RPL27A,TSR2,POLR2A,ATP5MC3,HNRNPH3,TFDP1,KHSRP,NAXE,BYSL,DDX52,ADA2,IER2,PTMS,NOP2,ALKBH5,ZNF107,SIRT2,TAF6L,SLC29A1,SNRPD3,MAPK14,SNAPC4,MBD4,EDC3,CYREN,EIF4A3,THADA,DPYSL2,IMPAD1,METTL14,PHTF1,KHDC4,ZBTB22,NDUFB9,KIF22,OGG1,ARID4A,ELOF1,COPS8,TDP1,RRM2,SOX4,DHX15,CHAF1A,UBTF,GEMIN5,PAF1,IARS2,PQBP1,COPS6,RPS26,RPS15,ZNF768,CIB1,MED13L,MEF2A,EPHX2,SRRT,NFATC3,ZNF449,BUD31,ZNF335,YBX1,ACAD8,N4BP2,ZNF189,VOPP1,TSTA3,CIC,ISG15,GNAS,NAP1L1,RBM25,CDCA5,TRMT10B,NUP62,ZFP90,RBBP4,HNRNPDL,NIPSNAP2,ZBTB24,MBD1,MMACHC,ASH1L,GNPNAT1,MPHOSPH8,CHERP,PLAGL2,NSD3,IRF3,CHD1,PAIP1,MEAF6,FARSA,ANKLE1,BABAM2,AKAP8,CHTOP,TMEM14C,RLIM,CGAS,ZNF500,BUD13,NDUFB1,RAD54B,ZNF317,AKNA,CBX4,EYA1,DBF4,KLF13,HDDC2,GART,CTNNBL1,PELO,BRD7,GINS1,SAMD4B,GTF3C6,TELO2,HMGN1,NASP,POLR3GL,ATP5MF,MEN1,ZNF407,SYMPK,SNRPA,TARS,HSPA1B,MAPK3,CNOT9,ATAD2,COX8A,ZRANB2,SRSF3,TATDN1,TYW1B |
| 2.637e-50 | -114.16 | cellular aromatic compound metabolic process | biological process | GO:0006725 | 4727 | 1041 | 17256 | 2622 |
ZBTB10,LACTB2,CCNL2,RBM4,ZNF275,RPL23A,USF1,RAD23B,UPRT,CRY2,ECD,ZNRD1,FTSJ3,ERCC1,ZNF559,GABPA,EHMT1,HNRNPF,WDHD1,MIER2,DIDO1,MCM2,GINS4,SMAD2,RAD18,RPS27A,MYO18A,COX5A,RNASEL,SMAD1,ZNF75A,SMNDC1,SLC25A33,HIVEP3,CLSPN,MUM1,DHX9,RAB23,PDCD7,PARN,CDC73,TFAP4,PDXP,SMC3,EFTUD2,GEMIN4,CPSF4,PABPC1,NSUN4,PPA1,LUC7L2,SRSF11,AGGF1,FOXK1,MTA2,SF3B6,TYW1,GTPBP4,USP10,BCLAF1,ELK1,KPNA1,ETS2,TYW5,ZNF830,KARS,PTTG1,SLC35B2,INO80E,RCOR3,RBM23,ZNF420,MTA1,GMEB1,NABP1,INTS12,ZNF226,GPD1L,ZC3H3,RPRD1B,CGGBP1,PDCL3,CPNE1,POLR2L,EID1,KAT7,CRNKL1,RPL38,E2F3,POLR2D,MEF2D,PPP2CA,LSM6,NSMCE2,SNRPG,PPP5C,COMMD10,ZNF445,SRSF6,TRMT6,HABP4,ABHD14B,ATP5F1B,WDR5,NEXMIF,RRP36,NEIL2,TUT4,RPA2,ZBTB45,HUWE1,ZNF260,ZNF710,GTF2H2,MED22,DDX24,LDHA,UTP20,SLC19A1,PARG,AEN,PARP10,THAP5,YTHDC2,RBM8A,SND1,FANCI,PAPOLA,KRR1,CREM,TET3,FANCL,GLIS2,INTS1,POP7,NOC2L,MTPN,RYBP,RPP25,RBX1,RAD51AP1,SNRPB,CDC6,UBE2V1,PBRM1,EAF2,UTP3,LUC7L,USP21,CHD3,ZNF367,E2F4,PRPF4,KPNA2,DVL1,BEND6,FAM208A,POT1,ZNF564,FUBP1,CTU2,ZCCHC9,PHB2,CENPF,CHCHD2,COX4I1,CDK13,CNOT11,RSAD1,ARID1B,SUB1,MLX,MBD2,SSBP3,XPA,ZNF746,CTR9,AHCY,RBM3,ICE2,LDB1,AMD1,ZNF761,RBM38,IRF5,RXRB,RPL36,PAXX,MBIP,COX7A2L,DTD1,RUVBL2,BCCIP,USP7,SART1,TRAF7,RPLP2,SUCLG1,ARID2,LAGE3,ZNF416,RRAGC,ATP6V1B2,PCBP1,ZNF121,NRF1,ZNF473,KMT5C,ZNF302,RPAP1,TARDBP,TOP1MT,AHCYL1,STRAP,SPIDR,ZNF583,PRPF19,KDM3B,MND1,POLR2G,ZNF780B,PPIE,DCLRE1C,SUGP1,DHX16,RBL1,UHRF2,XRCC3,SMAD4,RAD51D,SLC30A9,NADSYN1,NIFK,MCM10,MTERF1,AGO2,GTF3A,PAGR1,GTPBP3,POLR1B,ORC3,RNLS,RBM15B,YTHDC1,RHOA,RPRD1A,HMGN5,PRKDC,TOP3A,PCGF1,DDX23,L3MBTL3,NEIL3,BBX,E2F1,IMPDH1,RBPJ,TAF12,NR2F2,PGAM1,HIPK3,IFI16,TXN,MAX,CXXC1,USP39,NANS,UBE2I,MYEF2,PARK7,PA2G4,NOL11,FIZ1,ZNF200,TRA2B,TAF5L,SLC26A2,ZNF800,CDC5L,SRSF10,ZNF524,KLF10,NSUN2,USP22,CBFB,RFC2,CLNS1A,PRIM1,DOT1L,IWS1,HHEX,BRD2,RPS14,LUC7L3,BTF3,SLF1,CCDC59,PTOV1,PRPF38B,RECQL,COX5B,EWSR1,POLR2K,PRKAA1,GSPT2,RRM1,TATDN3,CYCS,SUPT7L,PRPF39,ZNF79,ZNF518A,VPS25,NDUFS7,YY1AP1,CNOT3,NPLOC4,WDR48,LHX8,EXOSC7,MSH2,TPST1,CYC1,MRM3,PRIM2,CPQ,ELL2,ZNF574,RPS24,EXOSC9,ARID1A,MTR,TWISTNB,PHF6,XRCC5,MTHFD2,RBMX,MED15,PIAS2,CEBPG,GPI,NUDT3,ZNF511,ATXN3,TP53RK,UROD,C2orf49,CD320,SPINDOC,LPIN2,ADCY9,RNASEH2A,AQR,CDK12,SAP30,BRD4,DRAP1,ELP4,EDF1,TRIM28,SUPT16H,ZNF282,RAD51C,HINT1,DGCR8,SAFB,FTSJ1,ATF6,BEND3,XRCC4,EYA2,PRPF4B,NDUFS1,DEPDC1,MECP2,TKT,ARGLU1,HMG20A,WWP2,RFWD3,CCNK,DNAJC8,NDUFA2,ELP5,FUT8,AXIN2,RPL19,CARF,CITED2,NDUFA3,MSH6,KAT2A,RFXANK,ADSL,BMS1,KCNQ1,COMMD4,KLF6,CBX3,RPL32,ZHX1,DUSP11,DDX5,NDUFS5,WDR62,TAF6,PURA,DDB1,RORB,POLA2,CCNC,ZNF76,KMT2E,UQCR10,PHRF1,COMMD5,ATP5PF,ZNF696,SF3B2,GOT2,JAZF1,RPF2,GPATCH1,TCEA1,CARMIL1,CARM1,SRPK2,DEAF1,LARS,SNRNP200,RIOX2,SREK1,KMT2C,PRPSAP1,MPC1,ASF1B,RPL37,BRWD1,U2SURP,CRCP,BAZ1B,ZNF268,CHEK2,UBE2D3,NSMCE4A,ZCCHC8,NACA,RPL15,PM20D2,THRAP3,TTF1,PRPF18,LYAR,DTL,MED10,ATP5IF1,POLR2I,NUDT4,SUGP2,RPL6,SLTM,DAPK3,UAP1,NFIL3,DNPH1,SNRNP70,TSEN15,ADNP2,TCF12,MDH2,PMS2,UCK2,SMARCA4,UCK1,ORC1,MXD1,HNRNPA2B1,SAP130,RRN3,IARS,CD3EAP,EXOSC1,UTP4,ZNF770,CSTF1,POU2AF1,HPDL,METTL2A,SMU1,PCGF6,ATXN1,LSM8,OGDH,MBD3,FANCE,RPS9,PDHX,PON2,DUS3L,HNRNPR,STAT6,ARNTL,MAPK1,BRD9,CWC25,NAT14,DNAJC2,TRIP12,ZNF316,SHPRH,SCYL1,PAWR,MXD4,KMT5A,PPIG,DUS2,NABP2,ANP32A,NDUFS8,ERI3,FBL,STAT3,MYO5A,AMPD2,TGFB1,PPP1R9B,HEMK1,PSPC1,HELB,MIER1,NADK2,RCOR1,TFEB,UPF1,ZC3H7B,KMT2B,ACAT1,ZMIZ1,SLF2,TERF1,KDM4A,DHX8,EDRF1,PABPC4,CIPC,NSRP1,SRSF4,PDS5B,PCBP2,KCNAB2,ZNF672,TOPORS,STOML2,BRMS1,ZNF689,VIPAS39,SMG9,TFDP2,E2F2,PFKP,SSRP1,DDX42,NDUFV2,TOP2B,EZH1,RAVER2,MCTS1,DDX56,INTS7,MCM5,ZNF326,RTCB,FOXN2,CARS2,ETV3,RB1CC1,ZMYND11,DHX29,TEX10,MYBL2,RPS10,SRSF5,MPG,CBFA2T2,POLR2J,SETD3,CNOT6,MDH1,SGF29,ZNF296,SARNP,TRERF1,IVNS1ABP,UBR2,CHD1L,RMI2,CREBL2,EFL1,ZNF267,TCF19,PRKACA,SAFB2,APP,SP100,ZKSCAN1,UTP18,DUT,GRSF1,RBM15,ATF2,ADCY7,ENPP4,INTS13,RNPS1,WBP2,ATP6V0A1,NDUFA7,TAZ,DDX17,CHCHD3,TAF2,NT5C3B,HIPK2,RPLP1,RBMS1,FUS,PDXK,ZBTB11,GEN1,ZNF786,GALK1,RPS2,JMJD6,ETS1,ZNF92,PNO1,KRI1,ERH,SUV39H2,GATC,NDUFB4,PPP1R8,PRDM4,GEMIN6,DCP1A,HNRNPM,LDHB,PDPK1,TK1,GUK1,POLK,ZNF512,PDE3B,DDX39A,RPA1,ZNF180,ZNF862,KEAP1,POLE,TATDN2,PITX1,PML,LRPPRC,SLC25A19,HMGB2,USF2,COX15,DDX47,THOC1,GNPDA1,GPBP1L1,CSNK2A1,EBNA1BP2,BIRC2,LIN9,PCNA,ZNF639,XRCC2,TRMU,ETV6,PPCDC,MYBL1,MCMBP,CCAR1,METTL1,SP3,EXOSC6,BAZ2A,HARS,MRPL12,BRCA1,PRKRA,TONSL,QRSL1,DHFR2,ZNF45,OSGEPL1,NUDT11,GEMIN7,SEPHS2,CTCF,ASXL2,RLF,RB1,SNRNP25,MED8,CMTR2,TIMELESS,MDFIC,MAML1,ABCC1,PREB,UTP15,RTF1,EIF2AK1,ZNF174,PALB2,SYNCRIP,PRPS2,TBPL1,PRMT7,ATP5F1A,NDUFA5,UGP2,FOXM1,XAB2,DYNLL1,MRPL39,SUMO2,RPAIN,COMMD8,RPL11,RAD23A,CSDE1,ZBTB21,DUS4L,SAP30L,DVL2,RPL29,RPL35,BTG2,CPOX,NFATC2,PRPF3,KDM1B,TXNL4A,RPSA,SRSF1,ZNF700,MAFK,NDUFA11,DNAJC17,ZNF436,NCOA1,SLC25A39,INTS2,CTDP1,CDC40,RRP15,GNE,CDT1,ARID5A,SMC6,NKRF,RMI1,WRNIP1,IRF4,NDUFV1,CWC27,SS18L1,DDX31,PTGES3,ZNF202,ZMYM5,PPWD1,BIRC5,TFE3,CDCA7L,PPCS,ZNF496,NDUFB6,CCNB1,COMMD6,POLR3K,UTP25,SNUPN,RNASEK,PARPBP,DNMT1,NOL8,ELOA,DDX20,MRNIP,AMDHD2,MAK16,RBM47,WDR4,DHTKD1,UQCRH,RRS1,ARRB2,HDAC2,LIME1,MUT,CHTF18,NDUFA4,NOTCH2,PMF1,METTL3,JMY,NDUFS4,KLF16,ATIC,HDAC7,CTPS1,ATP6V0A2,EEF1D,TERF2,DDX28,PHF10,ZNF84,DCTD,PKM,KDM3A,SF3A2,PATL1,ADSS,EPRS,SERTAD2,ZNF777,ZFP92,DCK,QARS,ACLY,YY1,CDK2,RNF14,NRBP1,DNMT3A,SUZ12,SF3B1,ZBTB37,OLA1,ADPGK,SDE2,SDHA,FLAD1,TERF2IP,ZNF75D,KDM2A,UCHL5,TALDO1,MRM2,RFC3,ERF,TAOK1,SLBP,GAR1,POLG2,DHX57,CENPU,PRDM11,NSA2,VEZF1,GUCY1B1,FAAP100,TBL3,PPA2,STAT1,H2AFX,PDCD11,ATMIN,CSNK1D,POLQ,POU3F2,NCOR2,TWNK,BABAM1,TCF3,MYNN,BLM,SPR,FOXO3,MAD2L2,GTF2F1,RBM17,RPL17,COPS7B,UPF2,CREB1,CNOT6L,NCOA2,TSHZ1,ZFP64,RNASEH2C,TRIR,WDR18,RPL8,PARP4,ILF3,TBRG4,RPL27A,TSR2,POLR2A,ATP5MC3,HNRNPH3,TFDP1,KHSRP,NAXE,BYSL,DDX52,ADA2,IER2,PTMS,NOP2,ALKBH5,ZNF107,SIRT2,TAF6L,SLC29A1,SNRPD3,MAPK14,SNAPC4,EDC3,MBD4,CYREN,EIF4A3,THADA,DPYSL2,IMPAD1,METTL14,PHTF1,AKR1B1,KHDC4,ZBTB22,NDUFB9,KIF22,OGG1,ARID4A,ELOF1,COPS8,TDP1,RRM2,SOX4,DHX15,CHAF1A,UBTF,GEMIN5,PAF1,IARS2,PQBP1,COPS6,RPS26,RPS15,ZNF768,CIB1,MED13L,MEF2A,EPHX2,SRRT,NFATC3,ZNF449,BUD31,ZNF335,YBX1,BCL2,ACAD8,N4BP2,ZNF189,VOPP1,TSTA3,CIC,ISG15,GNAS,NAP1L1,RBM25,CDCA5,NUP62,TRMT10B,ZFP90,RBBP4,NIPSNAP2,HNRNPDL,ZBTB24,MBD1,MMACHC,ASH1L,GNPNAT1,MPHOSPH8,CHERP,PLAGL2,NSD3,IRF3,CHD1,PAIP1,MEAF6,FARSA,ANKLE1,BABAM2,AKAP8,CHTOP,TMEM14C,RLIM,CGAS,ZNF500,BUD13,NDUFB1,RAD54B,ZNF317,AKNA,CBX4,EYA1,DBF4,KLF13,HDDC2,GART,CTNNBL1,PELO,BRD7,GINS1,SAMD4B,GTF3C6,TELO2,HMGN1,NASP,POLR3GL,MEN1,ATP5MF,ZNF407,SYMPK,SNRPA,TARS,HSPA1B,MAPK3,CNOT9,ATAD2,COX8A,ZRANB2,SRSF3,TATDN1,TYW1B |
| 2.665e-48 | -109.54 | cellular macromolecule metabolic process | biological process | GO:0044260 | 6600 | 1341 | 17256 | 2622 |
ZBTB10,HEXB,TGOLN2,CCNL2,RBM4,ZNF275,FBXO22,EEF2K,RPL23A,USF1,RAD23B,DNM2,CRY2,ECD,RNF26,ZNRD1,TIPARP,ANKRD9,MGAT5,FTSJ3,MRPL57,USP34,ERCC1,ZNF559,NRAS,GABPA,EHMT1,WDHD1,MIER2,DIDO1,MCM2,ARF4,GINS4,SMAD2,RAD18,RPS27A,MYO18A,OGT,RNASEL,KLHL42,SMAD1,CHPF2,ZNF75A,SLC25A33,ZNF720,HIVEP3,CLSPN,GGA1,MUM1,TRIO,DHX9,KCTD17,EIF2AK4,PSMD9,APH1B,PARN,CDC73,ATG4A,TFAP4,PDXP,SMC3,RNFT1,FBXO7,EFTUD2,MRPL21,CPSF4,NUP85,PABPC1,PHKG2,NSUN4,PPA1,SRSF11,EIF3L,FOXK1,MAPKAPK3,MTA2,ERO1A,USP10,BCLAF1,MRPL16,ELK1,EIF4H,FNTA,KPNA1,ETS2,WIPI2,ZNF830,CFAP20,MRPL3,NUP58,ALS2,TRIM41,KARS,PTTG1,INO80E,RCOR3,CPNE3,FBXL6,ZNF420,MTA1,UBA5,GMEB1,NABP1,NSFL1C,INTS12,ZNF226,RPRD1B,CGGBP1,CPNE1,ULK3,SEC61B,POLR2L,EID1,KAT7,RPL38,E2F3,POLR2D,MEF2D,RAB1A,PPP2CA,LSM6,NSMCE2,CAMKMT,RNF38,DMWD,SNRPG,PPP5C,USP13,COMMD10,ZNF445,SRSF6,ZFP91,TRMT6,CCM2,HABP4,WDR5,NEXMIF,NEIL2,TUT4,PPP1R3B,GOLM1,RPA2,ZBTB45,PSMD2,HUWE1,ZNF260,NAA50,LTN1,KANSL2,UBE3B,ST8SIA2,ZNF710,FBXL19,GTF2H2,RPL22L1,MED22,SPTAN1,USP42,PICALM,MAGT1,GPS2,DBI,CD81,PARP10,WDR45B,THAP5,TRIM11,RBM8A,SND1,FANCI,PAPOLA,ZER1,CREM,TET3,FANCL,RAB8A,NUP210,GLIS2,IL6ST,INTS1,NOC2L,EIF5,ASB6,RYBP,PLK1,PTPN18,RBX1,APH1A,RAD51AP1,SNRPB,CDC6,UBE2V1,PBRM1,EAF2,KRTCAP2,USP21,TRIM4,ALG3,CHD3,ZNF367,E2F4,ARRDC1,KPNA2,DVL1,BEND6,FAM208A,NGLY1,POT1,ZNF564,FUBP1,RMND5A,ZCCHC9,PHB2,CENPF,LAMTOR3,SDC2,CHCHD2,ADCK5,CDK13,RAB6A,CNOT11,ARID1B,C1GALT1,SUB1,MLX,UBE2Q2,CCP110,MBD2,SSBP3,XPA,ZNF746,CTR9,ICE2,MRPL48,LRSAM1,DCAF8,LDB1,MAP4K3,ZNF761,METTL22,ARMC8,STYXL1,NMT2,IRF5,RXRB,RPL36,PAXX,MBIP,GALNT2,ZDHHC7,DTD1,RUVBL2,ECPAS,BCCIP,USP7,TRAF7,RPLP2,ARID2,ZNF416,RRAGC,LYN,ZNF121,MRPL50,NRF1,PSMA6,ZNF473,KMT5C,BRPF3,ZNF302,ABRAXAS2,PIN1,PPME1,RPAP1,TARDBP,LMAN1,TOP1MT,SPIDR,CTDSP2,SPSB3,ZNF583,PRPF19,SNX25,PPIF,KDM3B,MND1,BIRC3,POLR2G,ZNF780B,PPT1,RAB7A,PPIE,NUP155,DCLRE1C,MRPS14,EIF3H,IDE,RBL1,UBXN2B,FASTK,STK38,UHRF2,CHMP4B,XRCC3,H3F3A,SMAD4,RAD51D,SLC30A9,NIFK,MCM10,MTERF1,KLHL21,AGO2,CDCA8,TMX3,GTF3A,CDK11B,PAGR1,SCYL2,DNAJB9,HERC3,GTPBP3,CTSS,POLR1B,ORC3,RNF5,RBM15B,RHOA,RPRD1A,HMGN5,PRKDC,TUFM,TOP3A,RANGAP1,PCGF1,NEK1,L3MBTL3,NEIL3,BBX,E2F1,USP20,RBPJ,TAF12,NR2F2,HIPK3,IFI16,TXN,NUP188,MAX,PDCD6IP,GXYLT1,ADAM10,PRKCSH,CXXC1,CUL1,USP39,GYG1,UBE2I,MYEF2,PARK7,ASPHD2,PA2G4,NOL11,FIZ1,ZNF200,FBXW2,AP2B1,TAF5L,MARCH2,ZNF800,CDC5L,ZNF524,KLF10,NSUN2,USP22,CBFB,RFC2,EIF3A,PRIM1,DOT1L,IWS1,MAP3K4,HHEX,MKNK1,BRD2,RPS14,TPP2,MRPL27,BTF3,PTPDC1,SLF1,CCDC59,B4GALT2,PTOV1,RECQL,EWSR1,DHPS,POLR2K,GSPT2,PRKAA1,RRM1,TATDN3,B4GALT1,CYCS,SUPT7L,ZNF79,ZNF518A,PSEN1,TMEM165,VPS25,YY1AP1,CNOT3,NPLOC4,WDR48,RPN1,LHX8,EXOSC7,KLHL5,ZNRF2,PPP4R1,MSH2,TPST1,DAPK1,PIGG,FBXL7,MRPL40,MRM3,APOL1,SOCS5,EIF5A,PIGT,PRIM2,ELL2,COQ8A,USF3,MFNG,ZNF574,RPS24,EXOSC9,ARID1A,ADRB2,MAP2K2,TWISTNB,PHF6,XRCC5,DERL1,CAT,GOLGA2,EPOP,RBMX,MED15,PIAS2,USP32,CEBPG,ZNF511,NDC1,ATXN3,TP53RK,RAB11B,RAF1,SPINDOC,CCNA2,SIAH1,MTMR4,LPIN2,SOCS6,MRPS27,TTC3,RNASEH2A,AQR,ILKAP,CDK12,CFL1,SAP30,BRD4,DRAP1,ELP4,EDF1,PKMYT1,ASB13,ERC1,SERP1,TRIM28,SUPT16H,EIF3K,ANKZF1,ZNF282,RAD51C,HINT1,DDOST,SAFB,FTSJ1,ATF6,BEND3,XRCC4,EYA2,PRPF4B,DEPDC1,B4GALT5,MANBA,MECP2,CBLL1,ARGLU1,SECISBP2,POFUT1,HMG20A,WWP2,RFWD3,CCNK,ELP5,FUT8,PTPN11,AXIN2,MRPL54,FEM1B,RPL19,CARF,CITED2,MSH6,KAT2A,LONRF3,RFXANK,FBXO9,OTUD3,ARSK,GUF1,COMMD4,KLF6,SPPL2B,SH3GLB1,CBX3,RPL32,ZHX1,PPP1R11,DUSP11,DDX5,WDR91,TAF6,PURA,DDB1,RORB,POLA2,CCNC,ZNF76,PIGM,KMT2E,PHRF1,UBE2Q1,PTP4A3,COMMD5,MRPL19,ZNF696,PCYOX1L,CDC42,JAZF1,TCEA1,SLC35C2,CARM1,SRPK2,DEAF1,LARS,NCK1,VHL,RIOX2,SUMF2,KMT2C,ASF1B,RPL37,MAN2A2,BRWD1,PPM1G,CRCP,CAB39,BAZ1B,STK11,ZNF268,CHEK2,VPS4A,MRPL13,DCAF5,CAPN1,UBE2D3,NSMCE4A,PPP1R2,PPP1R12A,GORASP1,NACA,UBXN1,RPL15,THRAP3,TTF1,NUP205,PRPF18,LYAR,DTL,MED10,PYURF,ZRANB1,CSNK1G3,POLR2I,ERLIN1,RPL6,EIF2A,SYVN1,VKORC1,SLTM,DAPK3,MASTL,KLHL15,NFIL3,SIAH2,FN3KRP,CTSA,ADNP2,TCF12,PRKAB1,MDH2,PMS2,SMARCA4,ORC1,EXT2,MXD1,USP5,SAP130,RRN3,UBXN2A,IARS,CD3EAP,KIF14,EXOSC1,PPP6C,UTP4,ZNF770,CSTF1,POU2AF1,PGGT1B,RNF25,METTL2A,PCGF6,ATXN1,OGDH,EDEM2,TOLLIP,MBD3,FANCE,RPS9,STAT6,ARNTL,FKBP5,MAPK1,BRD9,ABCA1,PDF,NAT14,DNAJC2,TRIP12,ZNF316,SHPRH,RAE1,SCYL1,NUP54,PAWR,MXD4,DCUN1D4,GFM2,SPPL2A,FASTKD3,FGFR3,GRK2,KLHL20,KMT5A,PPIG,RRBP1,NABP2,ANP32A,FBL,ERI3,STAT3,SLC35A1,B3GALT6,TGFB1,DCAF6,HEMK1,HELB,PSPC1,MIER1,RFFL,RCOR1,PRMT2,CDK11A,TFEB,MTMR3,CTSL,UPF1,DTX4,KMT2B,ZMIZ1,PLOD3,HRAS,SLF2,TERF1,FGFR1OP,ADD1,MAP3K7CL,MRPS15,KDM4A,PIGQ,XIAP,EDRF1,PABPC4,CDK5,CIPC,PSMD1,NEK6,SRSF4,PDS5B,FNIP2,NUP153,SENP1,PCBP2,PGAP2,PLK3,ZNF672,TMEM115,MRPL43,TOPORS,DCUN1D5,ICMT,STOML2,BRMS1,ZNF689,AXIN1,LIMK1,ATE1,VIPAS39,ST3GAL2,SMG9,FBXL3,TFDP2,E2F2,LONP2,AAAS,SSRP1,MRPL9,MRPS2,TOP2B,EZH1,ZNRF3,MCTS1,DDRGK1,EIF2S2,INTS7,MCM5,ZNF326,FOXN2,CARS2,UBE2QL1,NAGPA,ETV3,RB1CC1,DHX29,ZMYND11,MAN1B1,MYBL2,RPS10,ARMT1,SRSF5,MPG,CBFA2T2,ABCF1,PTPRF,POLR2J,CSK,DUSP3,SETD3,TEX30,PTAR1,CNOT6,HEXA,RNF139,SGF29,EGLN1,ZNF296,SARNP,ABCA3,TRERF1,IVNS1ABP,UBR2,CHD1L,RMI2,WDTC1,CREBL2,RXYLT1,EFL1,ZNF267,SAFB2,PRKACA,TCF19,STAM,APP,KTN1,ANKIB1,PRKD3,SP100,ZKSCAN1,DUT,DDA1,NUP107,ANAPC7,MAVS,RNF19A,CLN6,ATF2,RNF169,MAP4K4,INTS13,RNPS1,WBP2,NDUFA7,FKBP3,DDX17,CHCHD3,TAF2,PEX5,CDC16,NT5C3B,HIPK2,RPLP1,RBMS1,ZBTB11,GEN1,ZNF786,RPS2,TRAK1,JMJD6,UBE4A,ETS1,ZNF92,FBXO3,CAPN2,SUV39H2,GATC,PPP1R8,PRDM4,DCP1A,GTSE1,TTLL12,LYPLA2,PDPK1,PPP3CA,TK1,TNFAIP3,POLK,ZNF512,MRPS10,DDX39A,RPA1,ZNF862,ZNF180,KEAP1,POLE,TATDN2,PITX1,MAPK6,PML,LRPPRC,HMGB2,USF2,ANAPC4,FAF1,THOC1,GPBP1L1,PPP1R15B,CSNK2A1,BIRC2,LIN9,ABL2,PCNA,ZNF639,ETV6,XRCC2,MCMBP,MYBL1,CCAR1,MRPL32,PTPRK,CDC37,SP3,METTL1,EXOSC6,BAZ2A,HARS,TLK1,MRPL12,GMFB,EZR,BRCA1,PRKRA,TONSL,SOCS4,QRSL1,ACTB,ZNF45,NAA60,TMUB1,CTCF,PPP3CB,B4GALT4,RLF,ASXL2,RB1,NUS1,MED8,CMTR2,PPIL2,TIMELESS,MDFIC,MAML1,PREB,UTP15,RTF1,EIF2AK1,KRAS,UBE4B,NFATC2IP,LY6E,EIF4G2,ZDHHC3,ZNF174,PSMC4,PALB2,CDC27,TBPL1,PRMT7,RNF114,KCTD7,CYLD,UGP2,FOXM1,XAB2,DYNLL1,MRPL39,SUMO2,DUSP22,RPAIN,COMMD8,RPL11,RAD23A,SEC11A,CSDE1,PDK2,ZBTB21,MDM2,MRPL34,MINPP1,SAP30L,DVL2,RPL29,RPL35,PSMA8,BTG2,MTMR6,NFATC2,KDM1B,USP36,RPSA,SRSF1,DNAJC10,MRPL2,CLK3,ZNF700,MAFK,PSMD3,ZNF436,DNAJC17,NCOA1,LTA4H,AP2S1,USP53,ZC3HC1,INTS2,CTDP1,CDC40,CDT1,ARID5A,SMC6,NKRF,SUMF1,GGA2,CSNK1A1,RMI1,TFRC,WRNIP1,PTPN2,IRF4,CWC27,SS18L1,PTGES3,CAMK2G,CNTN5,ZNF202,ZMYM5,PPWD1,FBXO41,GOLGA7,BIRC5,TFE3,CDCA7L,SPCS3,RPS6KC1,UBE2C,GCSH,ZNF496,ZDHHC8,NHLRC3,CCNB1,EIF1B,COMMD6,POLR3K,PARPBP,CDC25B,MAST2,DNMT1,SEH1L,AKT2,PBK,ELOA,MRNIP,GALNT7,AURKB,CCNF,MCFD2,STT3A,PSMD8,WDR4,EIF2D,PTPN7,ITGB1,ARRB2,ZNF598,HDAC2,DDX58,WSB2,PPIB,GMFG,CHTF18,MAN2B1,NOTCH2,PMF1,METTL3,JMY,FKBP1A,RNF121,KLF16,DAD1,HDAC7,RNF135,EEF1D,TERF2,MORC3,PHF10,ZNF84,NOA1,KDM3A,PATL1,PSMB3,EPRS,ZNF777,SERTAD2,ZFP92,QARS,CSNK1G1,PPP3R1,DCAF11,VCPIP1,MAP3K5,YY1,CDK2,RNF14,NRBP1,ZC3HAV1,DNMT3A,RWDD1,ZBTB37,RPS6KA1,SUZ12,EIF3D,RAC1,KLHL18,SDE2,TERF2IP,CRKL,APLP2,ZNF75D,KDM2A,SHC1,UCHL5,NAA35,MRM2,RFC3,ERF,TAOK1,CUL3,SLBP,KIAA1586,CDC23,POLG2,GAR1,PSMB9,CENPU,SOCS7,PRDM11,VEZF1,PPP2R5A,MRPL55,JAK1,FAAP100,SEL1L,STAT1,PPA2,H2AFX,TRIM32,B4GALT3,ATMIN,CSNK1D,POLQ,OTUD5,POU3F2,NCOR2,TWNK,TCF3,BABAM1,CDCA3,BRAP,MYNN,SDF2L1,BLM,RAB11A,FOXO3,MAD2L2,GTF2F1,RBM17,RPL17,PTEN,COPS7B,UPF2,OSTC,CREB1,MAP3K14,CNOT6L,UBE2M,NCOA2,TSHZ1,ZFP64,RNASEH2C,TRIR,NEK7,WDR18,RPL8,PARP4,ILF3,TBRG4,ANAPC2,RHOT1,RPL27A,MARK2,POLR2A,FBXO21,NUCB1,SGSH,HGS,TTLL4,PRDX3,TFDP1,KHSRP,CPEB2,MIB2,ADA2,PTMS,IER2,UBE2E2,NOP2,DCAF15,NF1,ALKBH5,MOGS,DNAJC24,ZNF107,UBE2Z,SIRT2,TAF6L,SNRPD3,UBQLN2,USP48,FKBP2,MAPK14,BECN1,SNAPC4,RNF103,EDC3,MBD4,UBLCP1,CYREN,THADA,EIF4A3,ATG3,IMPAD1,METTL14,PHTF1,KIF22,ZBTB22,JOSD1,OGG1,ARID4A,FGFR1OP2,TIMM50,ELOF1,COPS8,TDP1,TRIM8,DPM1,RRM2,WDR82,SOX4,STK17B,CHAF1A,UBTF,GEMIN5,PAF1,UEVLD,IARS2,PQBP1,ROCK1,GALNT10,COPS6,RPS26,PSMC1,RPS15,PIGN,ZNF768,UFC1,CIB1,MED13L,MEF2A,SRRT,RHBDD1,NFATC3,ZNF449,BUD31,ZNF335,BCL2,YBX1,UBE3C,ACAD8,ZNF189,VOPP1,CIC,PSMA1,ISG15,CAND1,GNAS,NAP1L1,CDCA5,TRMT10B,NUP62,ZFP90,NAA20,RBBP4,HNRNPDL,ZBTB24,MBD1,TOMM20,ASH1L,MPHOSPH8,WDYHV1,PLAGL2,NSD3,IRF3,CHD1,PAIP1,MEAF6,FARSA,ANKLE1,BABAM2,AKAP8,RPN2,CHTOP,PDIA6,SCYL3,ABI1,HTRA2,RLIM,ZNF500,PSMB7,EIF3G,BTBD1,RAD54B,ZNF317,DAP3,TAB2,CHCHD1,CANT1,USP11,AKNA,SMURF1,PPP2R2D,CBX4,MRPL42,SH2D3A,EYA1,MRPS26,DBF4,KLF13,MAN1A1,PELO,BRD7,MRPL11,SAMD4B,GINS1,ZDHHC18,TELO2,GTF3C6,CSNK1G2,HMGN1,ADAM17,NASP,PRKAR1B,POLR3GL,WDR81,MEN1,ZNF407,SYMPK,TARS,HSPA1B,MAPK3,CNOT9,PLAA,ATAD2,KBTBD7,MBD6,SRSF3,TATDN1 |
| 3.673e-48 | -109.22 | DODD_NASOPHARYNGEAL_CARCINOMA_DN | MSigDB lists | DODD_NASOPHARYNGEAL_CARCINOMA_DN | 1240 | 382 | 17377 | 2626 |
H2AFZ,GXYLT1,AP3M2,CUL1,PLXNA1,CCNB1,IKBIP,RBM4,FBXO22,PA2G4,NOL11,TRA2B,CISD2,SMARCE1,SENP1,SEH1L,SRSF10,SRP72,NRAS,AATF,PBK,NOL8,MKI67,KIF15,WDHD1,SMC2,CCNF,MCM2,PRIM1,KIF18B,RAD18,PDRG1,LUC7L3,WDR4,C1orf109,DHTKD1,UQCRH,CCDC59,NMD3,HDAC2,DDX58,RECQL,MAPRE1,MRPL9,ADO,RRM1,KIF23,PXMP2,CYCS,ZNRF3,EIF2AK4,SUPT7L,SPAG5,RTKN,FKBP1A,EIF2S2,KLHL5,INTS7,ATIC,RBM34,PHF14,MSH2,CYC1,CPSF4,FAM171A1,NUP85,PPA1,LUC7L2,SOCS5,IFRD1,ZNF84,PRIM2,GTPBP4,RPS24,DCTD,TOMM40,FXR1,PATL1,MTR,CCT8,PSMB3,FAS,XRCC5,DERL1,EPRS,MTHFD2,FNTA,RBMX,PPP3R1,NDE1,MRPL3,NUDT3,EGLN1,ZNF207,SARNP,SUZ12,URB2,PTTG1,OLA1,RMI2,TMEM97,TPX2,NUF2,ZNF267,STMN1,C19orf48,ANKIB1,ARL6IP6,FLAD1,CCNA2,AHCTF1,UTP18,MTMR4,UCHL5,DUT,GRSF1,UBA5,NUP107,INTS12,ANAPC7,RNASEH2A,C8orf59,RBM15,CDK12,ANKLE2,CCT2,RFC3,PSRC1,MKLN1,RNPS1,E2F3,POLR2D,SLBP,CDCA2,NUSAP1,GORAB,POLG2,MAT2A,CHCHD3,C19orf54,RAD51C,DSN1,LSM6,CCDC14,STAT1,LMBR1,SNRPG,XRCC4,TUBB,POLQ,ADAM23,PKP4,DEPDC1,TCF3,BRAP,MYNN,AGPAT3,SIKE1,HMG20A,PNO1,ZNF92,SLC25A36,SUV39H2,PTEN,CENPJ,FJX1,ZNF260,PRC1,NAA50,OSTC,MTX2,HNRNPM,MSH6,SMC4,JMJD4,TK1,ZNF512,ILF3,LDHA,ADSL,LLPH,RHOT1,DDX39A,KIF11,CBX3,C1orf131,KIF18A,MAGT1,PFDN4,TTLL4,LRPPRC,KHSRP,C4orf46,AEN,HMGB2,YWHAH,DDX52,S100PBP,ZBED3,PIGM,SKA3,DDX47,NOP2,HNRNPAB,THOC1,NF1,GNPDA1,UBE2Z,KIF2C,SND1,BRIX1,MRPL19,FANCI,PRNP,FANCL,LIN9,PCNA,TIMM23,DPYSL2,SLC44A1,ETV6,NDUFB9,MCMBP,FGFR1OP2,CCAR1,MRPL32,METTL1,LARS,LAP3,RAD51AP1,RRM2,PSMG1,CDC6,PITPNB,BRCA1,SOX4,ANLN,STX16,DHX15,RHEB,CHAF1A,TRAM2,FBXO28,ZNF367,U2SURP,BAZ1B,KPNA2,CHEK2,ZNF45,OSGEPL1,SASS6,FAM208A,POT1,STARD3NL,FUBP1,C1orf74,RPS15,PARP12,HJURP,CENPF,SDC2,TIA1,RACGAP1,PM20D2,NUP205,PRPF18,LYAR,DTL,SUB1,TIMELESS,YBX1,AHCY,KNTC1,UBE3C,NIPSNAP1,NTPCR,RPL6,PSMA1,CAND1,MASTL,NAP1L1,GALNT2,PALB2,CDC27,TMEM168,CDCA5,SLC16A1,NUP62,RBBP4,CCNB2,TSEN15,ZBTB24,ADNP2,TCF12,IMMT,FEZ2,FOXM1,ARID2,SUMO2,UCK2,PLAGL2,SMARCA4,ATP6V1B2,PAIP1,TMEM69,OIP5,HNRNPA2B1,RRN3,ZNF473,IARS,KIF14,CS,RPN2,CHTOP,MINPP1,LMAN1,F2R,STRAP,CSTF1,PPIF,MND1,NXT1,CPOX,NLN,DNAJC9,TOR1AIP2,NUP155,TXNL4A,RAD54B,SRSF1,ZNF317,RBL1,UBXN2B,CEP55,PROSER1,FKBP5,ZNF146,TMEM33,DNAJC2,MCM10,MRPL42,RRP15,CASP6,DBF4,NUP54,PAWR,NCAPG,BZW2,SCYL2,TFRC,FBXO5,SAC3D1,FASTKD3,GART,PELO,TANK,POLR1B,ORC3,FBL,GINS1,B3GALT6,RPRD1A,DCAF6,FAM49B,TIMMDC1,TMEM39A,ASPM,PRKDC,ABCF2,METTL5,ATP2C1,SNRPA,TARS,ZFR,ATAD2,TWSG1,BIRC5,NEIL3,E2F1,SRSF3,RBPJ,UBE2C |
| 9.535e-47 | -105.97 | protein binding | molecular function | GO:0005515 | 11470 | 2073 | 17224 | 2647 |
ZBTB10,HEXB,TGOLN2,CCNL2,SYNRG,FBXO22,EEF2K,THAP4,RAD23B,DNM2,FTSJ3,USP34,CCDC57,ERCC1,NRAS,EHMT1,KIF15,HNRNPF,WDHD1,MIER2,MCM2,RAB22A,MID1IP1,SMAD2,RPS27A,MYO18A,OGT,COX5A,KLHL42,SMAD1,ANXA11,GGA1,SEC61G,CCZ1,MUM1,TRIO,CUTA,RAB23,KCTD17,HAUS4,APH1B,PARN,CDC73,MYL6B,ATG4A,PDXP,SMC3,TNPO3,GEMIN4,MVP,PABPC1,NUP85,NSUN4,PPP6R1,IFRD1,AGGF1,RBM42,FOXK1,GTPBP4,MAP7D1,ELK1,EIF4H,MAGED2,KPNA1,ETS2,TYW5,YJU2,WIPI2,RUFY3,PDLIM5,ACSF2,RHOG,EXOC3,VTI1A,C5orf30,INO80E,RCOR3,LCLAT1,CPNE3,RBM23,ZNF420,TBC1D22A,TBC1D14,NSFL1C,SEPT11,GPD1L,ZC3H3,PDCL3,SNX8,EID1,POLR2D,HTATIP2,TMEM147,MEF2D,GSTCD,MAT2A,VPS26B,CORO1C,NSMCE2,CAMKMT,PPP5C,TUBB,COMMD10,SRSF6,CCM2,HABP4,FLOT1,BTN3A1,ABHD14B,ATP5F1B,HDGFL2,TUT4,PPP1R3B,GOLM1,HUWE1,ZNF260,NAA50,ANXA5,LTN1,KANSL2,NAP1L4,MED22,SPTAN1,STAU1,TCTEX1D2,DDX24,TACC1,USP42,LDHA,HEBP2,LLPH,RAB3IP,PICALM,TTC33,SH3BP5,PARG,ACOX1,FAM3C,AEN,PARP10,YWHAH,THAP5,GPATCH4,FAM129A,TRIM11,YTHDC2,RBM8A,SNX15,ENSA,NENF,SND1,RUFY1,KRR1,PRNP,RAB8A,NUP210,NOC2L,EIF5,TACC3,RYBP,PTPN18,MIOS,SNRPB,CDC6,PBRM1,UTP3,ODC1,USP21,TRAM2,FBXO28,GRIPAP1,ARRDC1,ADAM9,DVL1,NUMB,ZNF564,FUBP1,CTU2,CENPF,LAMTOR3,CHCHD2,NCKAP1,LYRM2,TNS3,SUB1,RINL,MBD2,SSBP3,KIF13B,XPA,AHCY,RBM3,GLE1,MRPL48,LRSAM1,HDHD2,CAMSAP1,METTL22,ICAM2,APPL1,BBS12,RXRB,SDHB,PCM1,GALNT2,NLRC5,RUVBL2,MYO9A,CCNB2,ECPAS,USP7,RPLP2,ARID2,SLC2A1,ATP6V1B2,LYN,PCBP1,BCAP31,VAV1,PSMA6,ZNF473,BRPF3,KMT5C,ZNF302,TARDBP,SPIDR,CTDSP2,PRPF19,PPIF,CLCN3,BIRC3,RAB7A,PPIE,CHMP2B,VDAC1,TMEM201,EIF3H,GLOD4,IDE,DHX16,UHRF2,CHMP4B,XRCC3,CYBC1,PARD3,BCL2L12,NIFK,MCM10,MTERF1,KLHL21,CDCA8,TMX3,ARF1,CDK11B,PAGR1,TUBGCP2,DNAJB9,HOMER1,WBP1L,POLR1B,RNF5,RBM15B,RHOA,RPRD1A,TOP3A,ARHGEF12,PCGF1,DDX23,RAB18,TRIM26,PDCD6,NEK1,ATP6V1D,FAM110A,L3MBTL3,TAF12,NR2F2,PGAM1,IFI16,TXN,H2AFZ,TMEM203,PRKCSH,USP39,UBE2I,PARK7,RAB4A,TRA2B,SUCLG2,CISD2,TAF5L,SMARCE1,CDC5L,ZNF524,OSBP2,USP22,CLNS1A,EIF3A,DOT1L,IWS1,ANKRD10,MKNK1,WAS,KIF18B,TPP2,C1orf109,ZMAT3,PRPF38B,RECQL,C9orf78,EWSR1,GADD45G,RRM1,DNAAF5,ACAP1,B4GALT1,CYCS,SUPT7L,WDR48,SPAG5,NPLOC4,CNOT3,RTKN,TMEM250,CEP104,EXOSC7,KLHL5,LRRC8D,PPP4R1,MSH2,OSTF1,MRPL40,SYTL3,APOL1,EIF5A,GCC2,ELL2,COQ8A,USF3,RPS24,GORASP2,CAPZA2,ADRB2,MTR,CCT8,PHF6,PFDN5,GOLGA2,RBMX,MED15,PIAS2,APPL2,CDKN2A,ZNF511,ATXN3,RAF1,EPM2A,CD320,CCNA2,MTMR4,BRI3,TAP2,AQR,TP53BP2,RBM12B,CDK12,ILKAP,SAP30,BRD4,DRAP1,NARF,LRRC8A,ELP4,PKMYT1,ASB13,SERP1,TRIM28,SUPT16H,EIF3K,CHMP4A,ATF6,XRCC4,PRPF4B,ADAM23,NDUFS1,DEPDC1,MECP2,SECISBP2,SPDL1,HMG20A,WWP2,JAKMIP1,CCNK,DNAJC8,ELP5,AXIN2,CITED2,JMJD4,KAT2A,TMEM126B,RABIF,PACS1,KCNQ1,OTUD3,MACF1,KLF6,COMMD4,KIF11,FADD,SMAP2,SH3GLB1,MYO1F,CBX3,INF2,TMEM127,PPP1R11,DDX5,WDR62,TAF6,ESPL1,PURA,DEF6,FAM83G,IPO4,DDB1,CCNC,NAT9,PTP4A3,UBE2Q1,SF3B2,CDC42,SYNM,GOT2,HADHB,CNNM3,CARM1,SRPK2,WDR41,LARS,ZCCHC10,RIOX2,TMEM216,KMT2C,OGFR,PRPSAP1,ASF1B,EIF4ENIF1,NIP7,U2SURP,MIA2,VPS4A,PPP1R2,RGS2,LYAR,FAM89B,TRAFD1,GBA,SYVN1,EIF2A,DAPK3,ARHGAP15,MASTL,UAP1,NFIL3,YWHAZ,TMEM14A,TOB1,ADNP2,TCF12,PRKAB1,MDH2,SMARCA4,ORC1,RRN3,UBXN2A,IARS,KIF14,EXOSC1,CLTB,DNAL4,CSTF1,CHP1,POU2AF1,UBQLN4,NXT1,PPP1R18,SELPLG,SMU1,ATXN1,LSM8,BICD2,CADM1,HERPUD2,TOLLIP,FANCE,MBD3,RPS9,PDHX,ALKBH6,SURF4,ARNTL,ANP32E,FKBP5,ABCA1,GCLM,RAE1,DCTN2,NUP54,CHIC2,PAWR,MXD4,DCUN1D4,PIP4K2A,FERMT3,KIF5B,KLHL20,SEC24C,DUS2,ARHGEF2,ANP32A,STAT3,MYO5A,NIPAL3,AMPD2,COA3,PHF20L1,DCAF6,FAM49B,COG1,RFFL,RCOR1,PRMT2,TFEB,LEMD2,CTSL,UPF1,ELMO1,ZC3H7B,HRAS,TERF1,SLF2,CCDC93,FGFR1OP,MAP3K7CL,AGPAT1,CNTROB,PPP1R16B,MIEN1,MIS12,CIPC,TTC9C,PDS5B,NUP153,SENP1,PGAP2,TMEM115,AATF,ARMH3,DCUN1D5,PLEKHF2,BRMS1,PWWP2B,WDR11,AXIN1,SMG9,LONP2,NDUFV2,PHF23,CERK,ITGB5,LMNA,MCTS1,EIF2S2,FOXN2,C16orf72,RB1CC1,PRRC2A,ZMYND11,MYBL2,ARMT1,UHRF1BP1,SRSF5,MPG,MATR3,CYB5A,NCDN,POLR2J,SETD3,CNOT6,NDE1,EGLN1,ZNF207,ANKRD27,PPP1R37,SARNP,TMEM97,MON1B,NUF2,TCF19,KTN1,APP,CLUAP1,PRKD3,ATP2A2,GRSF1,DUT,ANAPC7,FAM76B,RNF19A,CLN6,GCC1,RNF169,ATP6V1G1,RNPS1,FKBP3,DDX17,CHCHD3,PEX5,CDC16,HIPK2,NT5C3B,TICAM1,PDXK,NKAPD1,TMBIM4,ANXA6,GMCL1,UBE4A,ETS1,CAPN2,ADD3,SUV39H2,TPCN1,HNRNPM,LYPLA2,LDHB,PPP3CA,JTB,EMP3,MTMR12,ZP3,PDE3B,CIP2A,KIF18A,CCDC6,WNT5B,MAPK6,C4orf46,RGL1,PSAP,IGBP1,FAF1,SNAPIN,AGRN,THOC1,GNPDA1,PPP1R15B,CSNK2A1,EBNA1BP2,BIRC2,GIT2,ATPAF1,ABL2,DLG5,XRCC2,ZFYVE27,MCMBP,PTPRK,CDC37,SP3,METTL1,HARS,GMFB,ESYT1,ANLN,RAB5B,RHEB,DPYSL3,TBC1D17,CDCA4,TONSL,NRM,ACTB,SINHCAF,TMUB1,CTCF,DOCK11,ASXL2,CRLF3,LRRC14,NUS1,MDFIC,AFF1,MAML1,CYTH1,NQO2,UTP15,EIF2AK1,EIF4G2,ITPRIPL1,CDC27,SNAP23,TBPL1,PRMT7,ATP5F1A,KCTD7,NDUFA5,CYLD,UGP2,FAM207A,DYNLL1,COPE,GGPS1,ABRACL,RAD23A,PDK2,ZBTB21,STRBP,TNFAIP8,PDCD2,SAP30L,CLPTM1,RPL29,TIMP2,BTG2,TUBGCP5,DNAJC9,MTMR6,NFATC2,KDM1B,USP36,ATP1A1,CLK3,MAFK,PSMD3,CEP55,ZNF436,PLGRKT,NCOA1,ZC3HC1,SMAP1,CDC40,DAP,GNE,SMC6,ARFIP2,NKRF,BZW2,WRNIP1,SS18L1,PTGES3,CAMK2G,MLEC,ZNF202,FAM50B,RHOT2,NEU1,GOLGA7,TWSG1,PGRMC1,GLG1,FAM126A,GUCD1,RPS6KC1,UBE2C,CCNB1,COMMD6,RIC1,UTP25,SNUPN,ASAP2,CNPY4,TFG,PLCL2,SPTSSA,SEH1L,ATG9A,PBK,ARHGAP45,MKI67,DDX20,AMDHD2,CCNF,WDR4,SARAF,TRAF5,HDAC2,PWWP2A,HSPH1,MAPRE1,CHTF18,KIF23,PMF1,NOTCH2,JMY,FKBP1A,SLC31A1,SNX18,ATIC,CTPS1,ATP6V0A2,RNF135,PIKFYVE,EEF1D,TMED2,FTL,PIP4K2C,PLEC,RIT1,CYFIP2,KDM3A,SF3A2,FAS,EPRS,CSNK1G1,QARS,DCAF11,PPP3R1,TCOF1,NRBP1,CABLES1,DNMT3A,CKLF,RWDD1,TRIP10,RPS6KA1,SF3B1,SUZ12,CAST,RAC1,OLA1,GNB2,FLAD1,APLP2,KDM2A,TNPO2,CDKN1B,TALDO1,GPX4,MAPRE2,RFC3,TAOK1,CUL3,SLBP,POLG2,PSMB9,H2AFV,GAR1,CENPU,DHX57,SOCS7,HSPA4,JAK1,TBL3,FAAP100,H2AFX,SEL1L,KLHDC4,PDCD11,CSNK1D,ATMIN,POLQ,POU3F2,NCOR2,PKP4,SCAMP3,TWNK,BABAM1,CDCA3,BLM,GTF2F1,TMCC3,RPL17,CRAT,AHSA1,PRC1,UPF2,COPS7B,CNOT6L,CNPY3,IFT46,UBE2M,ZFP64,STRIP1,DENND1B,DENND4C,TRIR,WDR18,ILF3,RHOT1,TSR2,MARK2,ECH1,PRDX1,POLR2A,GNA12,NUCB1,PLD3,PFDN4,PRDX3,HNRNPH3,STX18,TFDP1,NAXE,KHSRP,ASNA1,BYSL,SSSCA1,VPS29,S100PBP,MIB2,ADA2,NOP2,UBN1,DCAF15,NF1,UBE2Z,TAF6L,BECN1,MAPK14,RNF103,MBD4,CYREN,METTL14,ZNHIT6,RCSD1,SRI,KHDC4,KIF22,ZBTB22,NFU1,OGG1,ELOF1,COPS8,FYTTD1,TRIM8,RRM2,SOX4,PAF1,UBTF,CXXC4,SPATA2,ATXN2L,PQBP1,ROCK1,STARD3NL,RPS15,AGTRAP,CDIP1,CIB1,XPO7,SRRT,ZNF449,CAPZA1,KIFAP3,BCL2,GLTP,N4BP2,HP1BP3,ISG15,CAND1,GNAS,TSC1,RBM25,CDCA5,RBBP4,HNRNPDL,NIPSNAP2,ZBTB24,SMARCD1,WASF2,MBD1,MMACHC,TOMM20,FAM92A,MPHOSPH8,GNPNAT1,NSD3,CHD1,MEAF6,MIEF1,BABAM2,CCDC50,AKAP8,PARL,RPN2,CHTOP,F2R,ABI1,SCYL3,TMEM14C,HTRA2,RLIM,PSMB7,WIPF1,BOLA1,ERBIN,BUD13,PEF1,EIF3G,BTBD1,TAB2,TULP3,CHCHD1,WDR59,CANT1,SCARB1,GAS2,USP11,SMURF1,TSPAN5,PPP2R2D,MAGEH1,EYA1,CDK2AP2,LETMD1,KLF13,HDDC2,RGS1,FBXO5,PELO,TANK,BRD7,MRPL11,SAMD4B,GTF3C6,POLR3GL,WDR81,MEN1,MFN2,COX8A,ZRANB2,SRSF3,ATP6V1C1,TATDN1,TSC2,LACTB2,RBM4,CMTM6,RPL23A,CDKN2C,USF1,NAPG,DNAAF2,AP1M1,UPRT,CRY2,ECD,MOB1A,RNF26,LRRC59,BAK1,RHOBTB3,ZNF559,GABPA,NUTF2,WBP1,GINS4,ARF4,KRIT1,AHNAK,RAD18,PDRG1,RNASEL,OAZ1,PDCD4,SMNDC1,NXT2,CLSPN,RHOC,DHX9,PSMD9,HAUS2,COPB2,CD59,TFAP4,RIMS3,MEGF8,EFTUD2,FBXO7,MYDGF,CPSF4,PHKG2,LUC7L2,SRSF11,EIF3L,MAPKAPK3,MTA2,ERO1A,MTFR2,SF3B6,SSR2,USP10,ITM2A,BCLAF1,FNTA,PDLIM1,TXNDC16,CFAP20,TMEM159,ZNF830,NUP58,ALS2,FAM72A,KARS,TRIM41,NQO1,POC1A,ANK3,PTTG1,TPX2,TBC1D13,DAZAP2,GLRX3,STMN1,REPS1,ABHD16A,SH3BP1,MTA1,UBA5,NABP1,INTS12,MICU2,RPRD1B,CGGBP1,CPNE1,ULK3,SEC61B,POLR2L,FAM118B,KAT7,GOPC,E2F3,CIRBP,CRNKL1,GORAB,RAB1A,GIGYF1,KIF2A,PPP2CA,ALDH3B1,CCDC14,LSM6,SNRPG,USP13,MZT1,IP6K2,WDR5,IFT27,NEIL2,SAPCD2,SRXN1,RPA2,PSMD2,CLIC4,PDCD10,COQ4,ITGB8,ARF5,ARHGEF1,GTF2H2,FBXL19,UTP20,MAGT1,GPS2,DBI,SSNA1,MRFAP1L1,CD81,AAMDC,FANCI,CREM,PAPOLA,FANCL,TET3,GLIS2,TIMM23,IL6ST,POP7,ASB6,RPP25,PLK1,SEPT9,APH1A,RBX1,RAD51AP1,PSMG1,UBE2V1,EAF2,IL12RB1,LUC7L,ALG3,CHD3,E2F4,KPNA2,PRPF4,CLN3,NGLY1,FAM208A,MYL12B,POT1,CCDC137,RMND5A,HJURP,PHB2,DNAJB2,FAM53C,SDC2,NKD2,KLC1,CDK13,ADCK5,COX4I1,DNAJB1,RAB6A,CNOT11,ARID1B,C1GALT1,MLX,CCP110,ZNF746,ARL6IP1,CTR9,ICE2,NIPSNAP1,DCAF8,LDB1,ACSL3,MAP4K3,ARMC8,IRF5,RPL36,HAUS8,MBIP,PAXX,LAMTOR4,SIL1,FAM122A,UNC13C,BCCIP,SART1,TRAF7,TOR1AIP1,LAGE3,RRAGC,ZFYVE21,OIP5,NRF1,ABRAXAS2,PPME1,PIN1,RPAP1,AHCYL1,LMAN1,STRAP,SPSB3,SNX25,ARHGAP17,POLR2G,PPT1,KIAA0040,NUP155,DCLRE1C,RHBDF2,AFDN,SUGP1,RBL1,STK38,FASTK,UBXN2B,AP1S1,SLC22A23,H3F3A,SMAD4,CHID1,RAD51D,SLC30A9,NADSYN1,AGO2,HMGN3,NCAPG,SCYL2,FZD6,GTPBP3,CTSS,ORC3,YTHDC1,PRKDC,TUFM,RANGAP1,API5,HAGH,ZFR,SEC23IP,E2F1,USP20,RBPJ,PDCD6IP,MAX,ADAM10,CXXC1,TSC22D3,CUL1,GYG1,OAT,ANKRD26,MTFR1L,PA2G4,NOL11,FIZ1,AP2B1,FBXW2,MARCH2,SRSF10,SRP72,KLF10,LACTB,SUPT20H,RFC2,CBFB,RAB2B,MAP3K4,HHEX,BRD2,LUC7L3,RPS14,MAP4,MRPL27,BTF3,SLF1,NMD3,CCDC59,COX5B,SCOC,DHPS,C16orf87,PRKAA1,VAV2,GSPT2,DLGAP4,PXMP2,PSEN1,ZNF79,VPS25,PDXDC1,YY1AP1,NDUFS7,FAM192A,RPN1,LHX8,ARPC5,TPST1,DAPK1,PIK3IP1,MRM3,SOCS5,FDFT1,GID8,PIGT,CPQ,WDR1,C1orf35,EXOSC9,ARID1A,FXR1,PTTG1IP,GOSR1,MAP2K2,XRCC5,PI4K2A,HMGN2,AKAP1,CAT,SEC31A,DERL1,HSPBP1,CEBPG,ARAP1,FAM83D,USP32,GPI,CYTIP,TP53RK,REPS2,RAB11B,UROD,SLC39A13,BCL2L1,POMP,NUDT19,SPINDOC,RALB,SIAH1,MRPS27,SOCS6,TTC3,CFL1,ANKLE2,VDAC2,EDF1,EML4,ERC1,ANKZF1,RAD51C,DDOST,HINT1,DSN1,DGCR8,RAB24,SAFB,EFCAB14,NCLN,BEND3,EYA2,DYNC1LI2,TKT,CBLL1,ARGLU1,LANCL1,HLA-A,EBP,RFWD3,FUT8,BTF3L4,PTPN11,FEM1B,RPL19,CNN2,MTX2,MSH6,PDLIM2,FOCAD,LONRF3,RFXANK,FBXO9,SPPL2B,LTBP4,ZHX1,OAZ2,WDR91,POLA2,RORB,COPA,KMT2E,PHRF1,ABCB10,COMMD5,MAP1LC3B,DST,SIVA1,RAB35,TCEA1,CARMIL1,DEAF1,TRAPPC13,SNRNP200,NCK1,VHL,SREK1,ARHGDIB,HSPB11,PPM1G,SH3GLB2,BAZ1B,CAB39,CRCP,STK11,CLU,CHEK2,TSTD2,MRPL13,DCAF5,CAPN1,UBE2D3,NSMCE4A,PPP1R12A,GORASP1,ZCCHC8,UBXN1,C19orf25,RPL15,EPN1,THRAP3,NUP205,CHKA,DTL,MED10,PYURF,ORAI1,TENM3,ZRANB1,SLC12A2,MCPH1,ATP6V0D1,ATP5IF1,CREG1,NUDT4,ERLIN1,RPL6,KLHL15,SIAH2,SLC16A1,DNPH1,SNRNP70,EHD4,APOL2,N4BP2L2,CHMP2A,SNX27,FEZ2,CORO7,PMS2,EXT2,MXD1,USP5,HNRNPA2B1,NVL,PPP6C,CYB5R1,UTP4,RNF25,PCGF6,PON2,HNRNPR,HPS5,STAT6,MAPK1,BRD9,TMEM33,DNAJC2,TRIP12,SHPRH,SCYL1,VPS45,MYO9B,GFM2,SPPL2A,FASTKD3,FGFR3,GRK2,PPIG,KMT5A,NABP2,H2AFY,ATG13,FBL,FRMD8,MICAL3,TGFB1,PPP1R9B,ELOVL5,HEMK1,TIMMDC1,PSPC1,MIER1,NADK2,MTMR3,ACAT1,KMT2B,CENPT,PLOD3,RAB3IL1,RAB14,ADD1,KDM4A,XIAP,DHX8,GLUD1,ANKRD23,PABPC4,CALM2,CDK5,PSMD1,NEK6,NSRP1,RABGAP1L,SRSF4,FNIP2,SPATC1L,PCBP2,MLST8,PLK3,MRPL43,TOPORS,MCL1,SMC2,PPFIA3,STOML2,LIMK1,PRDX5,MLYCD,VIPAS39,ATE1,ATP6V0C,TFDP2,FBXL3,E2F2,PFKP,SSRP1,DDX42,MRPL9,STRN4,TOP2B,ZNRF3,DDRGK1,GNS,INPP5A,INTS7,MCM5,PHF14,RTCB,ZNF326,UBE2QL1,NAGPA,CYFIP1,ETV3,TSPYL4,DHX29,TEX10,RPS10,CBFA2T2,ABCF1,RHOB,PTPRF,SCARB2,CCDC86,CSK,DUSP3,SLAIN1,MDH1,HEXA,RNF139,SGF29,FAM208B,TRERF1,UBR2,ACTR3,CHD1L,WDTC1,MYH9,SAFB2,PRKACA,ANKIB1,STAM,RAB21,SP100,ZKSCAN1,DDA1,NUP107,ANKRD13C,MAVS,CEP63,ATF2,RBM15,DCTN1,SHOC2,PSRC1,MAP4K4,INTS13,WBP2,ATP6V0A1,NUSAP1,DNAJA1,TAF2,SEC61A1,RPLP1,RBMS1,FUS,LRP8,COIL,LRCH1,RPS2,SESTD1,TRAK1,SIKE1,JMJD6,AKT1S1,FBXO3,ERH,GATC,PPP1R8,PRDM4,GEMIN6,GTSE1,DCP1A,IMPA2,S100A6,NUDC,MOB4,PDPK1,TK1,TNFAIP3,KIAA0930,DDX39A,RPA1,ZNF180,ZNF862,KEAP1,POLE,CAPN7,PITX1,PML,LRPPRC,HMGB2,USF2,ANAPC4,SRM,DDX47,MCCC1,CDC42SE2,S1PR2,CDIPT,SEC16A,SSR1,LIN9,PCNA,ZNF639,PIK3R2,ETV6,PPCDC,TXLNA,FAM86C1,CCAR1,BAZ2A,PBXIP1,TLK1,MRPL12,LNX2,EZR,LRP5,BRCA1,PRKRA,STX16,EPB41,OPTN,SEPT1,SOCS4,QRSL1,NAA60,GEMIN7,RACGAP1,PPP3CB,RLF,RAPGEF6,RB1,SNRNP25,VASP,TIGAR,MED8,VMP1,PPIL2,MEA1,TIMELESS,TMEM8A,ALDH18A1,PREB,TRAPPC9,AACS,MEMO1,RTF1,KRAS,UBE4B,ARPC1A,ZNF174,PSMC4,GOLGA4,PALB2,SYNCRIP,PRPS2,RNF114,FOXM1,XAB2,SUMO2,COMMD8,RPL11,CSDE1,MDM2,CORO1A,METTL9,DVL2,POC5,CPOX,SLC26A6,PRPF3,TXNL4A,RPSA,SRSF1,DNAJC10,SCAP,PLEKHG4B,FAU,LTA4H,USP53,AP2S1,INTS2,CTDP1,MIF4GD,CDT1,ARID5A,SUMF1,GGA2,AP3S1,CSNK1A1,RMI1,TFRC,PTPN2,GSTK1,IRF4,STARD9,SLC35B4,DDX31,ABCD1,RPAP3,SNX2,ZMYM5,BORA,CHCHD6,KPNA4,CDKN2AIPNL,BIRC5,SNAP29,TFE3,CDCA7L,PKD2,ACADM,CHMP7,SAT2,GCSH,ZNF496,TAP1,YTHDF3,IKBIP,KIFC1,PARPBP,MAST2,CDC25B,PRADC1,DNMT1,NOL12,ORAI2,USO1,AKT2,NOL8,ELOA,MRNIP,AURKB,MCFD2,ZFAND5,SLC25A5,TMED10,STT3A,ITGB1,PTPN7,UQCRH,RRS1,ARRB2,ZNF598,RTN3,SVIP,DDX58,PPIB,GMFG,MUT,HLA-E,NDUFA4,MAN2B1,METTL3,CFLAR,MEX3C,HDAC7,GNAI2,ANKHD1,MORC3,TERF2,NOA1,SEPT8,DCTD,TOMM40,PKM,PATL1,PSMB3,ADSS,NSF,DCK,ACLY,PPP6R2,PPP6R3,MAP3K5,YY1,CDK2,RNF14,ZC3HAV1,MAGED1,EIF3D,KLHL18,AP1B1,SDHA,PAIP2,CRKL,PHC2,MOAP1,TERF2IP,CYHR1,SHC1,UCHL5,NAA35,TMBIM1,CDKN2AIP,CCT2,MKLN1,HMGN4,CDC23,SHCBP1,AP4E1,PPP2R5A,GUCY1B1,STAT1,TRIM32,RHEBL1,R3HCC1L,TCF3,MRI1,BRAP,SDF2L1,FOXO3,REEP5,RAB11A,CCDC28A,MAD2L2,PIP5K1C,MAT2B,RBM17,TEDC2,PTEN,CENPJ,TAGLN2,MAP3K14,CREB1,OSTC,NCOA2,PACS2,SMC4,NET1,NEK7,PARP4,TBRG4,ANAPC2,RPL27A,YIF1A,HGS,SLC38A7,TTLL4,MFAP1,CCDC69,ESYT2,SKA3,UBE2E2,NPHP4,HNRNPAB,ST13,PLXNC1,AGFG1,SIRT2,KIF2C,SNRPD3,UBQLN2,FKBP2,CUTC,EDC3,UBLCP1,RAP1A,EIF4A3,THADA,DPYSL2,ATG3,PPP1R12C,JOSD1,NDUFB9,RP2,TTC4,TECR,FGFR1OP2,TIMM50,TDP1,DPM1,WDR82,DHX15,CHAF1A,GEMIN5,TIMM29,COPS6,SASS6,RPS26,PSMC1,SLC12A7,TBC1D12,TM9SF4,UFC1,TIA1,MEF2A,EPHX2,NFATC3,BANF1,BUD31,ZNF335,YBX1,KNTC1,UBE3C,TSTA3,CIC,PSMA1,SEPT7,NAP1L1,NSMF,ODF2,EXOC4,NUP62,KIAA1328,MZT2B,PDSS2,TMEM106C,IMMT,CHERP,WDYHV1,IRF3,TWF2,PAIP1,ANKRD28,FARSA,ANKLE1,SAR1A,APOOL,PDIA6,CGAS,TOR1AIP2,AZI2,GFER,RAD54B,TMEM41A,ZNF317,DAP3,GADD45B,AKNA,REEP4,CBX4,MIF,KIF3B,GOLPH3L,SH2D3A,CASP6,SRGN,DBF4,TIMM21,SAC3D1,CTNNBL1,TTC17,TELO2,CSNK1G2,ADAM17,NASP,ASPM,PRKAR1B,SYMPK,SNRPA,TARS,HSPA1B,MAPK3,CNOT9,HLA-B,PLAA,ATAD2,ZNF330,KBTBD7 |
| 4.236e-46 | -104.48 | organic cyclic compound metabolic process | biological process | GO:1901360 | 4945 | 1063 | 17256 | 2622 |
ZBTB10,LACTB2,CCNL2,RBM4,ZNF275,RPL23A,USF1,RAD23B,UPRT,CRY2,ECD,ZNRD1,TIPARP,FTSJ3,ERCC1,ZNF559,GABPA,EHMT1,HNRNPF,WDHD1,MIER2,DIDO1,MCM2,GINS4,SMAD2,RAD18,RPS27A,MYO18A,COX5A,RNASEL,SMAD1,ZNF75A,SMNDC1,SLC25A33,HIVEP3,CLSPN,MUM1,DHX9,RAB23,PDCD7,PARN,CDC73,TFAP4,PDXP,SMC3,EFTUD2,GEMIN4,CPSF4,PABPC1,NSUN4,PPA1,LUC7L2,SRSF11,AGGF1,FOXK1,MTA2,SF3B6,TYW1,GTPBP4,USP10,BCLAF1,ELK1,KPNA1,ETS2,TYW5,ZNF830,KARS,PTTG1,SLC35B2,INO80E,RCOR3,RBM23,ZNF420,MTA1,GMEB1,NABP1,INTS12,ZNF226,GPD1L,ZC3H3,RPRD1B,CGGBP1,PDCL3,CPNE1,POLR2L,EID1,KAT7,CRNKL1,RPL38,E2F3,POLR2D,MEF2D,PPP2CA,LSM6,NSMCE2,SNRPG,PPP5C,COMMD10,ZNF445,SRSF6,TRMT6,HABP4,ABHD14B,ATP5F1B,WDR5,PMVK,NEXMIF,RRP36,NEIL2,TUT4,RPA2,ZBTB45,HUWE1,ZNF260,ZNF710,GTF2H2,MED22,DDX24,LDHA,UTP20,SLC19A1,PARG,AEN,PARP10,YWHAH,THAP5,YTHDC2,RBM8A,SND1,FANCI,PAPOLA,KRR1,CREM,TET3,FANCL,GLIS2,INTS1,POP7,NOC2L,MTPN,RYBP,RPP25,RBX1,RAD51AP1,SNRPB,CDC6,UBE2V1,PBRM1,EAF2,UTP3,LUC7L,USP21,CHD3,ZNF367,E2F4,PRPF4,KPNA2,DVL1,BEND6,FAM208A,POT1,ZNF564,FUBP1,CTU2,ZCCHC9,PHB2,CENPF,CHCHD2,COX4I1,CDK13,CNOT11,RSAD1,ARID1B,SUB1,MLX,MBD2,SSBP3,XPA,ZNF746,CTR9,AHCY,RBM3,ICE2,NSDHL,LDB1,AMD1,ZNF761,RBM38,IRF5,RXRB,RPL36,PAXX,MBIP,COX7A2L,DTD1,RUVBL2,BCCIP,USP7,SART1,TRAF7,RPLP2,SUCLG1,ARID2,LAGE3,ZNF416,RRAGC,ATP6V1B2,PCBP1,ZNF121,NRF1,ZNF473,KMT5C,ZNF302,RPAP1,TARDBP,TOP1MT,AHCYL1,STRAP,SPIDR,ZNF583,PRPF19,KDM3B,MND1,POLR2G,ZNF780B,PPIE,DCLRE1C,SUGP1,DHX16,RBL1,UHRF2,XRCC3,SMAD4,RAD51D,SLC30A9,NADSYN1,NIFK,MCM10,MTERF1,AGO2,GTF3A,PAGR1,GTPBP3,POLR1B,ORC3,RNLS,RBM15B,YTHDC1,RHOA,RPRD1A,HMGN5,PRKDC,TOP3A,PCGF1,DDX23,L3MBTL3,NEIL3,BBX,E2F1,IMPDH1,RBPJ,TAF12,NR2F2,PGAM1,HIPK3,IFI16,TXN,MAX,CXXC1,USP39,NANS,UBE2I,OAT,MYEF2,PARK7,PA2G4,NOL11,FIZ1,ZNF200,TRA2B,TAF5L,SLC26A2,ZNF800,CDC5L,SRSF10,ZNF524,KLF10,NSUN2,USP22,CBFB,RFC2,CLNS1A,PRIM1,DOT1L,IWS1,HHEX,BRD2,RPS14,LUC7L3,BTF3,SLF1,CCDC59,PTOV1,PRPF38B,RECQL,COX5B,EWSR1,POLR2K,PRKAA1,GSPT2,RRM1,TATDN3,CYCS,SUPT7L,PRPF39,ZNF79,ZNF518A,VPS25,NDUFS7,YY1AP1,NPLOC4,CNOT3,WDR48,LHX8,EXOSC7,MSH2,TPST1,CYC1,MRM3,APOL1,FDFT1,PRIM2,CPQ,ELL2,ZNF574,RPS24,EXOSC9,ARID1A,MTR,TWISTNB,PHF6,XRCC5,CAT,MTHFD2,RBMX,MED15,PIAS2,CEBPG,GPI,NUDT3,ZNF511,ATXN3,TP53RK,UROD,C2orf49,CD320,SPINDOC,LPIN2,ADCY9,RNASEH2A,AQR,CDK12,SAP30,BRD4,DRAP1,ELP4,EDF1,TRIM28,SUPT16H,ZNF282,RAD51C,HINT1,DGCR8,SAFB,FTSJ1,ATF6,BEND3,XRCC4,EYA2,PRPF4B,NDUFS1,DEPDC1,MECP2,TKT,ARGLU1,HMG20A,WWP2,EBP,RFWD3,CCNK,DNAJC8,NDUFA2,ELP5,FUT8,AXIN2,RPL19,CARF,CITED2,NDUFA3,MSH6,KAT2A,RFXANK,ADSL,BMS1,KCNQ1,COMMD4,KLF6,CBX3,RPL32,ZHX1,DUSP11,DDX5,NDUFS5,WDR62,TAF6,PURA,DDB1,RORB,POLA2,CCNC,ZNF76,KMT2E,UQCR10,PHRF1,COMMD5,ATP5PF,ZNF696,SF3B2,GOT2,JAZF1,RPF2,GPATCH1,TCEA1,CARMIL1,CARM1,SRPK2,DEAF1,LARS,SNRNP200,RIOX2,SREK1,KMT2C,PRPSAP1,MPC1,ASF1B,RPL37,BRWD1,U2SURP,CRCP,BAZ1B,ZNF268,CHEK2,UBE2D3,NSMCE4A,ZCCHC8,NACA,RPL15,PM20D2,THRAP3,TTF1,PRPF18,LYAR,DTL,MED10,ATP5IF1,POLR2I,ERLIN1,NUDT4,SUGP2,RPL6,SLTM,DAPK3,UAP1,NFIL3,DNPH1,SNRNP70,APOL2,TSEN15,ADNP2,TCF12,MDH2,PMS2,UCK2,SMARCA4,UCK1,ORC1,MXD1,HNRNPA2B1,SAP130,RRN3,IARS,CD3EAP,EXOSC1,CYB5R1,UTP4,ZNF770,CSTF1,POU2AF1,HPDL,METTL2A,SMU1,PCGF6,LSM8,ATXN1,OGDH,MBD3,FANCE,RPS9,PDHX,DUS3L,HNRNPR,STAT6,ARNTL,MAPK1,BRD9,ABCA1,CWC25,NAT14,DNAJC2,TRIP12,ZNF316,SHPRH,SCYL1,PAWR,MXD4,KMT5A,PPIG,DUS2,NABP2,ANP32A,NDUFS8,ERI3,FBL,STAT3,MYO5A,AMPD2,TGFB1,PPP1R9B,HEMK1,PSPC1,HELB,MIER1,NADK2,RCOR1,TFEB,UPF1,ZC3H7B,KMT2B,ACAT1,ZMIZ1,SLF2,TERF1,KDM4A,DHX8,EDRF1,PABPC4,CIPC,NSRP1,SRSF4,PDS5B,PCBP2,KCNAB2,ZNF672,TOPORS,STOML2,BRMS1,ZNF689,VIPAS39,SMG9,TFDP2,E2F2,PFKP,SSRP1,DDX42,NDUFV2,TOP2B,EZH1,RAVER2,MCTS1,DDX56,INTS7,MCM5,ZNF326,RTCB,FOXN2,CARS2,ETV3,RB1CC1,ZMYND11,DHX29,TEX10,MYBL2,RPS10,SRSF5,MPG,CBFA2T2,POLR2J,SETD3,CNOT6,MDH1,PLPP6,SGF29,ZNF296,SARNP,TRERF1,IVNS1ABP,UBR2,CHD1L,RMI2,CREBL2,EFL1,ZNF267,TCF19,PRKACA,SAFB2,APP,SP100,ZKSCAN1,UTP18,DUT,GRSF1,CLN6,RBM15,ATF2,ADCY7,ENPP4,INTS13,RNPS1,WBP2,ATP6V0A1,NDUFA7,TAZ,DDX17,CHCHD3,TAF2,NT5C3B,HIPK2,RPLP1,RBMS1,FUS,PDXK,ZBTB11,GEN1,ZNF786,GALK1,RPS2,JMJD6,ETS1,ZNF92,PNO1,KRI1,ERH,SUV39H2,GATC,NDUFB4,PPP1R8,PRDM4,GEMIN6,DCP1A,HNRNPM,LDHB,PDPK1,TK1,GUK1,POLK,ZNF512,PDE3B,DDX39A,RPA1,ZNF180,ZNF862,KEAP1,POLE,TATDN2,PITX1,PML,LRPPRC,SLC25A19,HMGB2,USF2,COX15,DDX47,THOC1,GNPDA1,GPBP1L1,MCCC1,CSNK2A1,EBNA1BP2,BIRC2,LIN9,PCNA,ZNF639,XRCC2,TRMU,ETV6,PPCDC,MYBL1,MCMBP,CCAR1,SP3,METTL1,EXOSC6,BAZ2A,HARS,MRPL12,LRP5,BRCA1,PRKRA,TONSL,QRSL1,DHFR2,ZNF45,OSGEPL1,NUDT11,GEMIN7,SEPHS2,CTCF,ASXL2,RLF,RB1,SNRNP25,MED8,CMTR2,TIMELESS,MDFIC,ALDH18A1,MAML1,ABCC1,PREB,UTP15,RTF1,EIF2AK1,ZNF174,PALB2,SYNCRIP,PRPS2,TBPL1,PRMT7,ATP5F1A,NDUFA5,UGP2,FOXM1,XAB2,DYNLL1,MRPL39,SUMO2,GGPS1,RPAIN,COMMD8,RPL11,RAD23A,CSDE1,ZBTB21,DUS4L,SAP30L,DVL2,RPL29,RPL35,BTG2,CPOX,NFATC2,PRPF3,KDM1B,TXNL4A,RPSA,SRSF1,SCAP,ZNF700,MAFK,NDUFA11,DNAJC17,ZNF436,NCOA1,SLC25A39,INTS2,CTDP1,CDC40,RRP15,CDT1,GNE,ARID5A,SMC6,NKRF,RMI1,WRNIP1,IRF4,NDUFV1,CWC27,SS18L1,DDX31,PTGES3,ZNF202,ZMYM5,PPWD1,BIRC5,TFE3,CDCA7L,PPCS,ZNF496,NDUFB6,CCNB1,COMMD6,POLR3K,UTP25,SNUPN,PARPBP,RNASEK,DNMT1,NOL8,ELOA,MRNIP,DDX20,AMDHD2,MAK16,RBM47,WDR4,DHTKD1,UQCRH,RRS1,ARRB2,HDAC2,LIME1,MUT,CHTF18,NDUFA4,NOTCH2,PMF1,METTL3,JMY,NDUFS4,KLF16,ATIC,HDAC7,CTPS1,ATP6V0A2,EEF1D,TERF2,DDX28,PHF10,ZNF84,DCTD,PKM,KDM3A,PATL1,SF3A2,ADSS,EPRS,SERTAD2,ZNF777,ZFP92,DCK,QARS,ACLY,YY1,CDK2,RNF14,NRBP1,DNMT3A,ZBTB37,SUZ12,SF3B1,OLA1,ADPGK,SDE2,SDHA,TERF2IP,FLAD1,ZNF75D,KDM2A,UCHL5,TALDO1,MRM2,RFC3,ERF,TAOK1,SLBP,GAR1,POLG2,DHX57,CENPU,PRDM11,NSA2,VEZF1,GUCY1B1,FAAP100,TBL3,PPA2,STAT1,H2AFX,PDCD11,ATMIN,CSNK1D,POLQ,POU3F2,NCOR2,TWNK,TCF3,BABAM1,MYNN,BLM,SPR,FOXO3,MAD2L2,GTF2F1,RBM17,RPL17,COPS7B,UPF2,CREB1,CNOT6L,NCOA2,TSHZ1,ZFP64,RNASEH2C,TRIR,WDR18,RPL8,PARP4,ILF3,TBRG4,RPL27A,TSR2,POLR2A,ATP5MC3,HNRNPH3,TFDP1,KHSRP,NAXE,BYSL,DDX52,ADA2,IER2,PTMS,NOP2,ALKBH5,ZNF107,SIRT2,TAF6L,SLC29A1,SNRPD3,MAPK14,SNAPC4,EDC3,MBD4,CYREN,EIF4A3,THADA,DPYSL2,IMPAD1,METTL14,PHTF1,AKR1B1,KHDC4,ZBTB22,NDUFB9,KIF22,OGG1,ARID4A,ELOF1,COPS8,TDP1,RRM2,SOX4,DHX15,CHAF1A,UBTF,GEMIN5,PAF1,IARS2,PQBP1,COPS6,RPS26,STARD3NL,RPS15,ZNF768,CIB1,MED13L,MEF2A,EPHX2,SRRT,NFATC3,ZNF449,BUD31,ZNF335,YBX1,BCL2,ACAD8,N4BP2,ZNF189,VOPP1,TSTA3,CIC,ISG15,GNAS,NAP1L1,RBM25,CDCA5,TRMT10B,NUP62,ZFP90,RBBP4,HNRNPDL,NIPSNAP2,ZBTB24,MBD1,MMACHC,ASH1L,GNPNAT1,MPHOSPH8,CHERP,PLAGL2,NSD3,IRF3,CHD1,PAIP1,MEAF6,FARSA,ANKLE1,BABAM2,AKAP8,CHTOP,TMEM14C,HTRA2,RLIM,CGAS,ZNF500,BUD13,NDUFB1,RAD54B,ZNF317,SCARB1,AKNA,CBX4,EYA1,DBF4,KLF13,HDDC2,GART,CTNNBL1,PELO,BRD7,SAMD4B,GINS1,GTF3C6,TELO2,HMGN1,NASP,POLR3GL,MEN1,ATP5MF,ZNF407,SYMPK,SNRPA,TARS,HSPA1B,MAPK3,CNOT9,ATAD2,COX8A,ZRANB2,SRSF3,TATDN1,TYW1B |
| 2.089e-44 | -100.58 | PUJANA_CHEK2_PCC_NETWORK | MSigDB lists | PUJANA_CHEK2_PCC_NETWORK | 737 | 261 | 17377 | 2626 |
H2AFZ,KDM4A,ABCC10,CCNB1,UBE2I,KIFC1,CDKN2C,PA2G4,ATP13A3,TRA2B,NUP153,TAF5L,MOB1A,DNMT1,SRSF10,PGAP2,SRP72,AATF,MKI67,HNRNPF,WDHD1,AURKB,SMC2,NUTF2,CCNF,MCM2,SLC25A5,CBFB,MAK16,RPS27A,TPP2,BTF3,RRS1,TFDP2,HDAC2,SMNDC1,SSRP1,HSPH1,NDUFV2,RECQL,EWSR1,SEC61G,RRM1,DHX9,CYCS,PSMD9,CNOT3,SPAG5,TFAP4,EIF2S2,SMC3,ATIC,MCM5,RBM34,MSH2,CPSF4,PABPC1,FDFT1,SRSF11,RB1CC1,MYBL2,ARID1A,TOMM40,EIF4H,CCT8,XRCC5,HMGN2,MTHFD2,POLR2J,DCK,RBMX,ACLY,CEBPG,PIAS2,YY1,MRPL3,KARS,URB2,SUZ12,PTTG1,STARD7,TPX2,STMN1,CCNA2,SP100,UTP18,DUT,MTA1,RNASEH2A,CCT2,RFC3,HMGN4,CDC123,SLBP,CDC23,H2AFV,MAT2A,NSA2,TAF2,RAD51C,HSPA4,ACYP1,LSM6,FTSJ1,SNRPG,USP13,TCF3,FAM76A,SIKE1,BLM,PNO1,ERH,PDCD10,AHSA1,PPP1R8,GTSE1,NAP1L4,MTX2,TMX1,HNRNPM,MSH6,SMC4,LDHB,ILF3,JTB,LDHA,ADSL,DDX39A,KIF11,PRDX1,RPA1,CBX3,UTP20,POLE,PRDX3,PFDN4,MFAP1,TATDN2,PARG,TFDP1,DBI,KHSRP,HMGB2,DUSP11,ESPL1,DDX52,CCNC,HNRNPAB,NOP2,NF1,CSNK2A1,DNAJC24,KIF2C,SNRPD3,MRPL19,FANCI,NUP210,PCNA,EIF4A3,TCEA1,OGG1,PLK1,SNRNP200,NCK1,DPM1,RAD51AP1,SNRPB,RRM2,CDC6,UTP3,BRCA1,PRKRA,ODC1,DHX15,EPB41,CHAF1A,HSPB11,IARS2,BAZ1B,PRPF4,KPNA2,CHEK2,POT1,FUBP1,RMND5A,UBE2D3,TM9SF4,CENPF,NACA,CTCF,TTF1,NUP205,RB1,CAPZA1,CTR9,TIMELESS,YBX1,KNTC1,RPL6,PSMA1,KRAS,NFATC2IP,NAP1L1,SYNCRIP,SLC16A1,NUP62,RBBP4,CCNB2,ADNP2,ZBTB24,SMARCD1,TMEM106C,IMMT,FOXM1,CHERP,UCK2,SMARCA4,PLAGL2,HNRNPA2B1,OIP5,PSMA6,IARS,SAR1A,KIF14,TARDBP,PRPF19,POU2AF1,POLR2G,DNAJC9,TXNL4A,EIF3H,SRSF1,HNRNPR,TIMM17A,PSMD3,ANP32E,MIF,DNAJC2,GOLIM4,CDT1,DBF4,HMGN3,GTF3A,AP3S1,TFRC,PTPN2,IRF4,SLC1A4,PPIG,FBL,GINS1,HMGN1,NASP,PRKDC,PCGF1,SNRPA,ZNF330,SRSF3,IDH3B,UBE2C,GCSH |
| 2.539e-44 | -100.38 | BRCA1 (BRCA1, DNA repair associated) | protein interactions | 672 | 967 | 328 | 17029 | 2761 |
FGFR1OP,PDCD6IP,PRKCSH,XIAP,YTHDF3,CCNB1,UBE2I,PABPC4,RPL23A,KIFC1,ANKRD26,PA2G4,PSMD1,NOL11,RAD23B,AP1M1,AP2B1,TRA2B,CRY2,NUP153,TFG,LRRC59,DNMT1,PCBP2,CDC5L,SRP72,USO1,ELOA,MKI67,HNRNPF,MCM2,RFC2,EIF3A,RCC1L,AHNAK,SMAD2,RAD18,RPS14,TPP2,MAP4,OGT,AAAS,PFKP,HDAC2,SSRP1,HSPH1,EWSR1,CLSPN,POLR2K,DHPS,DHX9,KIF23,PRPF39,PSMD9,COPB2,LMNA,WDR48,TFAP4,SMC3,MCM5,EFTUD2,ZNF326,CTPS1,MSH2,MVP,PPA1,PABPC1,PPP6R1,EEF1D,TERF2,EIF3L,MTA2,RPS24,PLEC,PKM,ELK1,MATR3,CCT8,XRCC5,SEC31A,EPRS,FNTA,POLR2J,ETS2,NSF,QARS,ACLY,MDH1,GPI,TCOF1,YY1,PPP6R3,CDK2,PDLIM5,ZC3HAV1,CDKN2A,KARS,NDC1,UBR2,SUZ12,SF3B1,TPX2,OLA1,MYH9,APLP2,CCNA2,UCHL5,NUP107,TALDO1,RPRD1B,GCC1,RNF169,MRM2,DCTN1,CCT2,CDKN2AIP,BRD4,MAP4K4,POLR2D,CDCA2,DNAJA1,GAR1,ERC1,TRIM28,SUPT16H,DDX17,PPP2CA,PEX5,CDC16,HSPA4,JAK1,TBL3,STAT1,RPLP1,RWDD4,H2AFX,FUS,TUBB,CSNK1D,RPS2,BABAM1,TKT,BRAP,WDR5,BLM,ETS1,FOXO3,GTF2F1,PSMD2,HUWE1,RPL17,ANXA5,CNN2,MAP3K14,CREB1,NCOA2,MSH6,HNRNPM,NUDC,SPTAN1,LDHB,STAU1,TCTEX1D2,DDX24,PARP4,RPL8,ILF3,LDHA,RPL27A,DDX39A,KIF11,PRDX1,POLR2A,RPA1,CBX3,KEAP1,RPL32,TATDN2,HNRNPH3,PARG,KHSRP,DDX5,PSAP,USF2,DDB1,UBE2E2,HNRNPAB,NOP2,COPA,CSNK2A1,EBNA1BP2,SND1,SNRPD3,SEC16A,BECN1,SF3B2,PCNA,TXLNA,KIF22,CARM1,CDC37,PLK1,LARS,SNRNP200,SEPT9,EZR,PSMG1,BRCA1,PRKRA,OGFR,DHX15,GEMIN5,UBTF,TONSL,E2F4,ATXN2L,KPNA2,CHEK2,PSMC1,UBE2D3,PHB2,ZCCHC8,CENPF,UBXN1,NACA,RPL15,DNAJB1,RB1,CAPZA1,YBX1,AHCY,BCL2,ALDH9A1,HP1BP3,POLR2I,RPL6,PSMA1,SEPT7,PSMC4,CAND1,RPL36,NAP1L1,SYNCRIP,PALB2,ODF2,FN3KRP,YWHAZ,RUVBL2,RBBP4,ECPAS,HNRNPDL,USP7,RPLP2,MDH2,SUMO2,COPE,HNRNPUL2,PMS2,SMARCA4,PCBP1,RPL11,ANKRD28,CSDE1,HNRNPA2B1,PSMA6,BABAM2,IARS,AKAP8,PPP6C,TARDBP,STRAP,UTP4,CSTF1,PRPF19,RPL29,RPL35,PPP1R18,POLR2G,CPOX,NUP155,PRPF3,DCLRE1C,RPS9,EIF3G,RPSA,EIF3H,SRSF1,DNAJC10,RBL1,HNRNPR,PSMD3,NCOA1,FAU,MAPK1,SMAD4,CMAS,AGO2,DBF4,NKRF,TFRC,FBXO5,KIF5B,GART,SEC24C,NABP2,BRD7,H2AFY,ORC3,FBL,STAT3,RPAP3,GTF3C6,PPP1R9B,RPRD1A,PRKDC,ABCF2,RANGAP1,BORA,TARS,ZFR,MAPK3,DDX23,UPF1,SEC23IP,E2F1,ZMIZ1,TERF1,IFI16 |
| 1.923e-43 | -98.36 | nucleic acid metabolic process | biological process | GO:0090304 | 3975 | 888 | 17256 | 2622 |
ZBTB10,KDM4A,DHX8,LACTB2,CCNL2,EDRF1,RBM4,ZNF275,PABPC4,RPL23A,USF1,CIPC,NSRP1,RAD23B,SRSF4,PDS5B,CRY2,ECD,ZNRD1,FTSJ3,PCBP2,ZNF672,ERCC1,ZNF559,GABPA,EHMT1,HNRNPF,WDHD1,MIER2,TOPORS,DIDO1,MCM2,GINS4,BRMS1,SMAD2,RAD18,RPS27A,ZNF689,MYO18A,VIPAS39,RNASEL,SMG9,TFDP2,SMAD1,E2F2,ZNF75A,SMNDC1,SLC25A33,DDX42,SSRP1,HIVEP3,CLSPN,MUM1,DHX9,TOP2B,EZH1,PDCD7,PARN,CDC73,MCTS1,RAVER2,TFAP4,DDX56,SMC3,INTS7,MCM5,EFTUD2,ZNF326,RTCB,FOXN2,GEMIN4,CPSF4,PABPC1,NSUN4,PPA1,LUC7L2,CARS2,SRSF11,AGGF1,ETV3,FOXK1,RB1CC1,DHX29,ZMYND11,MTA2,SF3B6,TEX10,TYW1,GTPBP4,RPS10,MYBL2,USP10,BCLAF1,SRSF5,CBFA2T2,MPG,ELK1,KPNA1,POLR2J,ETS2,SETD3,TYW5,CNOT6,ZNF830,SGF29,ZNF296,KARS,SARNP,TRERF1,IVNS1ABP,UBR2,CHD1L,PTTG1,RMI2,CREBL2,ZNF267,INO80E,SAFB2,PRKACA,RCOR3,TCF19,APP,RBM23,ZNF420,SP100,UTP18,ZKSCAN1,MTA1,GRSF1,DUT,GMEB1,NABP1,INTS12,ZNF226,ATF2,RBM15,ZC3H3,RPRD1B,CGGBP1,CPNE1,POLR2L,EID1,KAT7,INTS13,CRNKL1,WBP2,RPL38,POLR2D,RNPS1,E2F3,MEF2D,DDX17,TAF2,PPP2CA,CHCHD3,LSM6,NSMCE2,HIPK2,NT5C3B,RPLP1,RBMS1,FUS,SNRPG,PPP5C,GEN1,ZBTB11,COMMD10,ZNF786,RPS2,ZNF445,SRSF6,TRMT6,HABP4,JMJD6,WDR5,ETS1,NEXMIF,RRP36,PNO1,ZNF92,TUT4,NEIL2,KRI1,RPA2,ZBTB45,GATC,SUV39H2,HUWE1,PPP1R8,PRDM4,ZNF260,DCP1A,GEMIN6,ZNF710,GTF2H2,HNRNPM,MED22,PDPK1,TK1,DDX24,POLK,ZNF512,DDX39A,RPA1,UTP20,ZNF180,ZNF862,KEAP1,POLE,TATDN2,PITX1,LRPPRC,PML,AEN,HMGB2,USF2,THAP5,DDX47,THOC1,GPBP1L1,YTHDC2,RBM8A,CSNK2A1,EBNA1BP2,SND1,BIRC2,FANCI,PAPOLA,CREM,KRR1,LIN9,TET3,FANCL,PCNA,GLIS2,ZNF639,INTS1,ETV6,TRMU,XRCC2,POP7,NOC2L,MCMBP,MYBL1,CCAR1,RYBP,SP3,METTL1,RPP25,EXOSC6,RBX1,HARS,BAZ2A,RAD51AP1,SNRPB,MRPL12,CDC6,UBE2V1,PBRM1,EAF2,UTP3,BRCA1,PRKRA,LUC7L,USP21,TONSL,CHD3,ZNF367,E2F4,QRSL1,PRPF4,KPNA2,DVL1,OSGEPL1,ZNF45,BEND6,FAM208A,POT1,GEMIN7,ZNF564,FUBP1,SEPHS2,CTU2,ZCCHC9,PHB2,CENPF,CTCF,CHCHD2,CDK13,RLF,ASXL2,CNOT11,ARID1B,SNRNP25,SUB1,RB1,MLX,MED8,MBD2,CMTR2,SSBP3,XPA,ZNF746,CTR9,TIMELESS,MDFIC,RBM3,ICE2,MAML1,PREB,LDB1,UTP15,RTF1,ZNF761,RBM38,IRF5,ZNF174,RXRB,RPL36,PAXX,PALB2,SYNCRIP,TBPL1,PRMT7,DTD1,RUVBL2,BCCIP,USP7,SART1,TRAF7,RPLP2,ARID2,FOXM1,MRPL39,DYNLL1,XAB2,SUMO2,LAGE3,ZNF416,RRAGC,PCBP1,COMMD8,RPAIN,ZNF121,RAD23A,RPL11,CSDE1,ZBTB21,NRF1,ZNF473,KMT5C,DUS4L,ZNF302,RPAP1,TARDBP,TOP1MT,AHCYL1,STRAP,SAP30L,SPIDR,ZNF583,DVL2,PRPF19,KDM3B,MND1,RPL29,RPL35,POLR2G,ZNF780B,BTG2,PPIE,NFATC2,DCLRE1C,PRPF3,KDM1B,TXNL4A,RPSA,SRSF1,SUGP1,DHX16,ZNF700,RBL1,MAFK,ZNF436,UHRF2,DNAJC17,XRCC3,NCOA1,SMAD4,RAD51D,INTS2,SLC30A9,CTDP1,NIFK,MCM10,CDC40,MTERF1,RRP15,CDT1,AGO2,ARID5A,SMC6,GTF3A,NKRF,PAGR1,RMI1,WRNIP1,GTPBP3,IRF4,CWC27,DDX31,SS18L1,PTGES3,POLR1B,ORC3,RBM15B,YTHDC1,RPRD1A,HMGN5,PRKDC,ZNF202,ZMYM5,TOP3A,PPWD1,PCGF1,DDX23,BIRC5,L3MBTL3,NEIL3,TFE3,CDCA7L,BBX,E2F1,RBPJ,TAF12,NR2F2,HIPK3,IFI16,TXN,ZNF496,MAX,CXXC1,USP39,CCNB1,UBE2I,COMMD6,POLR3K,MYEF2,PARK7,UTP25,PA2G4,SNUPN,NOL11,PARPBP,FIZ1,RNASEK,ZNF200,TRA2B,TAF5L,DNMT1,ZNF800,CDC5L,SRSF10,ZNF524,KLF10,NOL8,NSUN2,ELOA,MRNIP,DDX20,USP22,RFC2,CBFB,MAK16,CLNS1A,PRIM1,IWS1,DOT1L,HHEX,RBM47,BRD2,RPS14,LUC7L3,WDR4,BTF3,RRS1,ARRB2,SLF1,CCDC59,HDAC2,PTOV1,PRPF38B,RECQL,EWSR1,LIME1,POLR2K,CHTF18,PRKAA1,GSPT2,RRM1,TATDN3,PMF1,NOTCH2,SUPT7L,PRPF39,ZNF79,ZNF518A,METTL3,VPS25,YY1AP1,NPLOC4,CNOT3,JMY,WDR48,LHX8,EXOSC7,KLF16,HDAC7,MSH2,MRM3,EEF1D,TERF2,PHF10,DDX28,ZNF84,PRIM2,ELL2,ZNF574,RPS24,EXOSC9,ARID1A,KDM3A,PATL1,SF3A2,TWISTNB,PHF6,XRCC5,EPRS,ZNF777,SERTAD2,ZFP92,RBMX,QARS,MED15,CEBPG,PIAS2,YY1,RNF14,CDK2,NRBP1,ZNF511,DNMT3A,ATXN3,TP53RK,ZBTB37,SF3B1,SUZ12,C2orf49,SDE2,TERF2IP,SPINDOC,ZNF75D,KDM2A,UCHL5,LPIN2,RNASEH2A,AQR,CDK12,MRM2,SAP30,BRD4,RFC3,ERF,DRAP1,TAOK1,SLBP,ELP4,EDF1,POLG2,GAR1,TRIM28,CENPU,DHX57,PRDM11,SUPT16H,NSA2,VEZF1,ZNF282,RAD51C,HINT1,DGCR8,SAFB,TBL3,FAAP100,H2AFX,STAT1,FTSJ1,PPA2,ATF6,BEND3,PDCD11,XRCC4,EYA2,ATMIN,CSNK1D,POLQ,PRPF4B,POU3F2,NCOR2,DEPDC1,TWNK,MECP2,TCF3,BABAM1,ARGLU1,MYNN,BLM,FOXO3,HMG20A,MAD2L2,WWP2,GTF2F1,RBM17,RFWD3,CCNK,DNAJC8,RPL17,ELP5,AXIN2,RPL19,UPF2,COPS7B,CARF,CITED2,CNOT6L,CREB1,MSH6,NCOA2,TSHZ1,ZFP64,KAT2A,RNASEH2C,TRIR,WDR18,ILF3,PARP4,RPL8,RFXANK,TBRG4,BMS1,RPL27A,COMMD4,KLF6,TSR2,POLR2A,CBX3,RPL32,ZHX1,HNRNPH3,TFDP1,KHSRP,DDX5,DUSP11,WDR62,TAF6,PURA,DDB1,BYSL,DDX52,RORB,CCNC,POLA2,ZNF76,PTMS,IER2,NOP2,KMT2E,PHRF1,ALKBH5,ZNF107,TAF6L,SIRT2,SNRPD3,COMMD5,MAPK14,SNAPC4,ZNF696,EDC3,SF3B2,MBD4,CYREN,EIF4A3,THADA,METTL14,JAZF1,PHTF1,RPF2,GPATCH1,KHDC4,KIF22,ZBTB22,TCEA1,OGG1,ARID4A,CARM1,ELOF1,SRPK2,COPS8,TDP1,DEAF1,LARS,SNRNP200,RIOX2,SREK1,RRM2,SOX4,KMT2C,ASF1B,DHX15,CHAF1A,RPL37,PAF1,GEMIN5,UBTF,BRWD1,U2SURP,PQBP1,IARS2,CRCP,BAZ1B,ZNF268,CHEK2,COPS6,RPS26,UBE2D3,RPS15,NSMCE4A,ZCCHC8,ZNF768,NACA,CIB1,MED13L,RPL15,MEF2A,THRAP3,TTF1,SRRT,PRPF18,LYAR,DTL,NFATC3,ZNF449,MED10,ZNF335,BUD31,YBX1,ACAD8,N4BP2,ZNF189,VOPP1,POLR2I,CIC,SUGP2,RPL6,SLTM,DAPK3,ISG15,GNAS,NAP1L1,RBM25,NFIL3,CDCA5,TRMT10B,NUP62,ZFP90,RBBP4,SNRNP70,HNRNPDL,TSEN15,ZBTB24,ADNP2,TCF12,MBD1,ASH1L,MPHOSPH8,CHERP,PMS2,SMARCA4,PLAGL2,NSD3,IRF3,ORC1,CHD1,MEAF6,MXD1,PAIP1,HNRNPA2B1,SAP130,FARSA,RRN3,ANKLE1,BABAM2,IARS,CD3EAP,EXOSC1,AKAP8,CHTOP,UTP4,ZNF770,RLIM,CSTF1,POU2AF1,ZNF500,METTL2A,SMU1,PCGF6,ATXN1,LSM8,BUD13,MBD3,FANCE,RPS9,RAD54B,ZNF317,DUS3L,HNRNPR,STAT6,ARNTL,AKNA,MAPK1,BRD9,CBX4,CWC25,NAT14,DNAJC2,TRIP12,ZNF316,SHPRH,EYA1,SCYL1,DBF4,KLF13,PAWR,MXD4,CTNNBL1,KMT5A,PPIG,PELO,DUS2,NABP2,BRD7,ANP32A,ERI3,FBL,STAT3,SAMD4B,GINS1,TELO2,GTF3C6,PPP1R9B,HEMK1,HMGN1,NASP,PSPC1,HELB,MIER1,POLR3GL,RCOR1,MEN1,ZNF407,SYMPK,SNRPA,TARS,MAPK3,TFEB,HSPA1B,CNOT9,UPF1,ATAD2,ZC3H7B,KMT2B,ZRANB2,SRSF3,TATDN1,ZMIZ1,SLF2,TERF1,TYW1B |
| 3.479e-42 | -95.46 | GO_CELL_CYCLE | MSigDB lists | GO_CELL_CYCLE | 1235 | 367 | 17377 | 2626 |
FGFR1OP,PDCD6IP,NUP188,TSC2,XIAP,USP39,CUL1,CNTROB,CCNB1,UBE2I,MIS12,KIFC1,CDK5,CALM2,CDKN2C,PA2G4,PSMD1,NEK6,PDS5B,DNM2,NUP153,CDC25B,SEH1L,MLST8,CDC5L,PLK3,PBK,NSUN2,MKI67,KIF15,AURKB,SMC2,USP22,CCNF,MCM2,PRIM1,KIF18B,RPS27A,PSMD8,MAP4,ITGB1,RRS1,TFDP2,E2F2,AAAS,ANXA11,MAPRE1,CLSPN,CHTF18,RHOC,PRKAA1,GSPT2,RRM1,KIF23,TOP2B,HAUS4,NOTCH2,PMF1,EIF2AK4,PSMD9,CDC73,HAUS2,JMY,LMNA,CNOT3,SPAG5,MCTS1,SMC3,SNX18,INTS7,MCM5,MSH2,FBXL7,GNAI2,NUP85,TERF2,PRIM2,RB1CC1,ZMYND11,MYBL2,PSMB3,RHOB,GOLGA2,ARAP1,APPL2,FAM83D,VCPIP1,CNOT6,NDE1,ZNF830,CDK2,CABLES1,CDKN2A,ZNF207,DNMT3A,RPS6KA1,UBR2,ACTR3,ANK3,PTTG1,TPX2,MYH9,NUF2,CREBL2,BCL2L1,PRKACA,STMN1,AHCTF1,CCNA2,RALB,SIAH1,NUP107,CDKN1B,SEPT11,ANAPC7,CEP63,TP53BP2,ATF2,DCTN1,ANKLE2,MAPRE2,PSRC1,BRD4,ERF,EID1,CDC123,TAOK1,CUL3,E2F3,SLBP,NUSAP1,CDCA2,PKMYT1,CDC23,RAB1A,PSMB9,EML4,TAF2,PPP2CA,KIF2A,RAD51C,CDC16,CHMP4A,DSN1,NSMCE2,H2AFX,PPP5C,CSNK1D,TUBB,BABAM1,CDCA3,BLM,RAB11A,MAD2L2,RFWD3,CCNK,RPA2,ERH,PSMD2,SUV39H2,PTEN,CENPJ,PRC1,PTPN11,NAA50,GTSE1,CNOT6L,MSH6,SMC4,NUDC,PPP3CA,TACC1,NEK7,JTB,TBRG4,ANAPC2,MACF1,KIF11,RPA1,KIF18A,POLE,GPS2,TFDP1,MAPK6,PML,SSNA1,WDR62,ESPL1,THAP5,SSSCA1,ANAPC4,POLA2,SKA3,GPR132,ENSA,CSNK2A1,KIF2C,SIRT2,MAPK14,BECN1,BIRC2,FANCI,PRNP,DST,LIN9,RAB8A,NUP210,PCNA,RAB35,XRCC2,KIF22,MCMBP,CARM1,CCAR1,PLK1,SEPT9,TLK1,RRM2,EZR,CDC6,PBRM1,BRCA1,SOX4,ANLN,RHEB,CHAF1A,OPTN,SEPT1,CHD3,E2F4,PPM1G,CAB39,STK11,ZNF268,VPS4A,CHEK2,SASS6,PSMC1,HJURP,PPP1R12A,PHB2,GORASP1,CENPF,CIB1,LAMTOR3,RACGAP1,RGS2,CRLF3,NUP205,DTL,RB1,CCP110,BANF1,TIMELESS,KNTC1,MCPH1,PSMA1,SEPT7,EIF4G2,APPL1,RBM38,DAPK3,HAUS8,MASTL,PSMC4,TSC1,PCM1,CDC27,ODF2,CDCA5,SIAH2,NUP62,RBBP4,CCNB2,BCCIP,SART1,CHMP2A,PRKAB1,CYLD,FOXM1,DYNLL1,RRAGC,SMARCA4,ORC1,OIP5,PSMA6,MDM2,PIN1,KIF14,AKAP8,PPP6C,CABLES2,POC5,PRPF19,MND1,BIRC3,BTG2,PSMB7,TUBGCP5,NUP155,AZI2,CHMP2B,TXNL4A,RAD54B,RBL1,PSMD3,CEP55,UHRF2,XRCC3,CHMP4B,GAS2,REEP4,MAPK1,PPP2R2D,PDCD2L,ZC3HC1,PARD3,RAD51D,KIF3B,CTDP1,MCM10,KLHL21,EYA1,RAE1,CDT1,DCTN2,DBF4,CDCA8,NUP54,CDK11B,CSNK1A1,NCAPG,TUBGCP2,FBXO5,SAC3D1,STARD9,PELO,BRD7,ARHGEF2,CENPM,ORC3,CAMK2G,GINS1,TGFB1,PPP1R9B,RHOA,NASP,ASPM,PRKDC,TOP3A,RANGAP1,WDR81,MEN1,BORA,CDK11A,MFN2,MAPK3,NEK1,UPF1,BIRC5,E2F1,PKD2,CENPT,CHMP7,UBE2C,HRAS,TERF1 |
| 9.764e-42 | -94.43 | cell part | cellular component | GO:0044464 | 16492 | 2614 | 18223 | 2701 |
HECA,ZBTB10,ABCC10,HEXB,TGOLN2,CCNL2,SYNRG,FBXO22,EEF2K,RAD23B,ATP13A3,DNM2,ZNRD1,FTSJ3,USP34,ERCC1,NRAS,EHMT1,KIF15,HNRNPF,WDHD1,MIER2,DIDO1,MCM2,RAB22A,SMAD2,MID1IP1,RPS27A,MYO18A,OGT,MPV17,COX5A,KLHL42,SMAD1,ZNF75A,ANXA11,SLC25A33,ZNF720,SEC61G,GGA1,MUM1,CCZ1,TRIO,RAB23,KCTD17,HAUS4,EIF2AK4,APH1B,PARN,CDC73,MYL6B,ATG4A,TMEM179B,PDXP,SMC3,TNPO3,GEMIN4,MVP,NUP85,PPP6R1,PABPC1,NSUN4,PPA1,IFRD1,AGGF1,FOXK1,RBM42,GTPBP4,MAP7D1,MRPL16,ELK1,EIF4H,RDH11,MAGED2,KPNA1,ETS2,TYW5,WIPI2,RUFY3,PDLIM5,ACSF2,FAM72D,RHOG,EXOC3,STARD7,VTI1A,C5orf30,SLC35B2,INO80E,LCLAT1,RCOR3,CPNE3,KIAA1147,RBM23,ZNF420,AHCTF1,TBC1D22A,TBC1D14,GMEB1,NSFL1C,SEPT11,ZNF226,GPD1L,ZC3H3,ARL5A,PDCL3,SNX8,ERMP1,EID1,IDH3A,NBPF11,POLR2D,HTATIP2,MEF2D,TMEM147,GSTCD,TANC1,MAT2A,VPS26B,NSMCE2,CORO1C,CAMKMT,PPP5C,PITRM1,TUBB,COMMD10,ZNF445,SRSF6,HABP4,CCM2,FLOT1,BTN3A1,ATG2B,ABHD14B,ATP5F1B,HDGFL2,NEXMIF,TUT4,PPP1R3B,GOLM1,ZBTB45,HUWE1,ZNF260,NAA50,ANXA5,LTN1,KANSL2,UBE3B,NAP1L4,ZNF710,ST8SIA2,RPL22L1,MED22,SPTAN1,STAU1,TCTEX1D2,DDX24,TACC1,USP42,MRS2,LDHA,HEBP2,LLPH,RAB3IP,PICALM,SH3BP5,SLC19A1,PARG,ACOX1,FAM3C,AEN,PARP10,YWHAH,WDR45B,THAP5,FAM129A,TRIM11,YTHDC2,SNX15,RBM8A,ENSA,NENF,SND1,RUFY1,TRIM65,ZER1,PRNP,KRR1,RAB8A,NUP210,NOC2L,EIF5,TACC3,RYBP,PTPN18,MIOS,SNRPB,CDC6,UTP3,PBRM1,ODC1,USP21,TRAM2,FBXO28,GRIPAP1,ARRDC1,ADAM9,DVL1,NUMB,ZNF564,FUBP1,CTU2,PARP12,ZCCHC9,CENPF,LAMTOR3,CHCHD2,NCKAP1,RSAD1,TNS3,SUB1,RINL,SSBP3,KIF13B,MBD2,XPA,AHCY,RBM3,GLE1,MRPL48,LRSAM1,NSDHL,AMD1,CAMSAP1,ZNF761,METTL22,ICAM2,STYXL1,APPL1,BBS12,RXRB,SDHB,PCM1,GALNT2,TMEM168,NLRC5,RUVBL2,BTBD10,MYO9A,ECPAS,CCNB2,USP7,GLT8D1,RPLP2,SUCLG1,ARID2,TMX4,SLC2A1,ATP6V1B2,PCBP1,LYN,BCAP31,VAV1,MRPL50,PSMA6,ZNF473,ZNF302,KMT5C,BRPF3,TARDBP,BCAP29,CTDSP2,SPIDR,PRPF19,PPIF,KDM3B,MND1,CLCN3,BIRC3,RAB7A,PPIE,CHMP2B,VDAC1,EIF3H,TMEM201,GLOD4,IDE,DHX16,UHRF2,CHMP4B,XRCC3,PARD3,BCL2L12,NIFK,MCM10,C19orf53,MTERF1,KLHL21,PDAP1,CDCA8,TMX3,GTF3A,ARF1,SLC12A9,CDK11B,PAGR1,TUBGCP2,DNAJB9,HOMER1,POLR1B,RNF5,RBM15B,PPAN,RHOA,RPRD1A,BTAF1,TOP3A,ARHGEF12,PCGF1,DDX23,RAB18,CACNB1,TRIM26,PDCD6,ATP6V1D,NEK1,L3MBTL3,FAM110A,NEIL3,CTBS,BBX,IMPDH1,TAF12,NR2F2,PGAM1,ARHGAP23,HIPK3,IFI16,TXN,NUP188,H2AFZ,PNISR,TMEM203,PRKCSH,USP39,UBE2I,PARK7,SLC25A37,GLMP,RAB4A,TRA2B,SUCLG2,CISD2,TAF5L,SMARCE1,ZNF800,CDC5L,ZNF524,SGCE,OSBP2,NSUN2,USP22,CLNS1A,EIF3A,ZMYM3,DOT1L,IWS1,MKNK1,WAS,KIF18B,TPP2,C1orf109,ZMAT3,FAM72C,B4GALT2,PRPF38B,RECQL,C9orf78,EWSR1,GADD45G,RRM1,DNAAF5,ACAP1,B4GALT1,CYCS,FAM136A,SUPT7L,ZNF518A,TMEM165,NPLOC4,CNOT3,SPAG5,WDR48,RTKN,TMEM250,CEP104,EXOSC7,KLHL5,LRRC8D,PPP4R1,MSH2,PIGG,OSTF1,FBXL7,MRPL40,TNRC18,SYTL3,APOL1,EIF5A,GCC2,PRIM2,COQ8A,ELL2,RDH10,MFNG,USF3,RPS24,GORASP2,CAPZA2,ADRB2,CCT8,MTR,PHF6,PFDN5,SLCO4A1,GOLGA2,EPOP,RBMX,MED15,PIAS2,APPL2,SAMD8,NUDT3,CDKN2A,ZNF511,NDC1,ATXN3,RAF1,C2orf49,CD320,EPM2A,CCNA2,MTMR4,BRI3,TAP2,TP53BP2,AQR,ILKAP,CDK12,SAP30,BRD4,DRAP1,NARF,LRRC8A,ELP4,ABHD11,PKMYT1,ASB13,SERP1,TRIM28,SUPT16H,EIF3K,CHMP4A,CERS6,ATF6,XRCC4,PRPF4B,ADAM23,NDUFS1,DEPDC1,MECP2,SECISBP2,SPDL1,HMG20A,WWP2,JAKMIP1,SLC25A36,CCNK,DNAJC8,ELP5,AXIN2,CARF,CITED2,ANKRD37,KAT2A,TMEM126B,RABIF,ADSL,PACS1,BMS1,KCNQ1,OTUD3,ARSK,MACF1,KIF11,COMMD4,KLF6,SMAP2,FADD,SH3GLB1,MYO1F,CBX3,SELENOW,TMEM127,INF2,PPP1R11,DUSP11,DDX5,WDR62,TAF6,ESPL1,PURA,DDB1,DEF6,IPO4,FAM83G,UBL3,CCNC,PIGM,LYRM4,GPR132,UBE2Q1,PTP4A3,BRIX1,MRPL19,ZNF696,SF3B2,PCYOX1L,CDC42,SYNM,GOT2,JAZF1,HADHB,RPF2,SLC35C2,CNNM3,CARM1,SRPK2,WDR41,LARS,LRBA,TMEM216,RIOX2,SUMF2,KMT2C,OGFR,MPC1,ASF1B,RPL37,MAN2A2,EIF4ENIF1,NIP7,U2SURP,MIA2,ZNF268,VPS4A,ATP6V0E1,PPP1R2,PM20D2,XPNPEP3,RGS2,LYAR,FAM89B,EI24,POLR2I,SUGP2,GBA,EIF2A,SYVN1,DAPK3,ARHGAP15,MASTL,UAP1,NFIL3,FN3KRP,YWHAZ,CTSA,TMEM14A,TOB1,TSEN15,ADNP2,TCF12,PRKAB1,MDH2,SMARCA4,ORC1,RRN3,UBXN2A,IARS,CD3EAP,KIF14,EXOSC1,CS,CLTB,DNAL4,CSTF1,CHP1,POU2AF1,UBQLN4,NXT1,PPP1R18,PGGT1B,SELPLG,SMU1,ATXN1,LSM8,GLO1,OGDH,BICD2,CADM1,EDEM2,TOLLIP,FANCE,MBD3,PDHX,RPS9,ALKBH6,SURF4,DUS3L,ARNTL,ANP32E,FKBP5,CCDC125,ABCA1,PDCD2L,CWC25,GCLM,ZNF316,RAE1,DCTN2,NUP54,CHIC2,PAWR,MXD4,DCUN1D4,PIP4K2A,XPR1,FERMT3,KIF5B,KLHL20,SEC24C,RRBP1,DUS2,ARHGEF2,ANP32A,LDLRAD3,STAT3,MYO5A,AMPD2,TXNL1,COA3,PHF20L1,DCAF6,FAM49B,ATP2C1,RFFL,COG1,RCOR1,PRMT2,TFEB,LEMD2,CTSL,UPF1,ELMO1,ZC3H7B,DTX4,ZMIZ1,TERF1,HRAS,SLF2,CCDC93,FGFR1OP,TMED7,MAP3K7CL,PIGQ,AGPAT1,CNTROB,PPP1R16B,EDRF1,MIEN1,MIS12,CIPC,GSDMB,PDS5B,NUP153,SENP1,PGAP2,TMEM115,AATF,DCUN1D5,PLEKHF2,BRMS1,PWWP2B,TRIM47,WDR11,AXIN1,SMG9,TRIM52,LONP2,NDUFV2,PHF23,CERK,SLC4A2,EZH1,ITGB5,LMNA,MCTS1,DDX56,EIF2S2,SLC38A5,FOXN2,CARS2,PRRC2A,RB1CC1,ZMYND11,PGS1,MYBL2,SRSF5,MPG,MATR3,CYB5A,NCDN,POLR2J,SETD3,TEX30,PTAR1,CNOT6,NDE1,PLPP6,EGLN1,ZNF207,ANKRD27,ABCA3,SARNP,IVNS1ABP,MON1B,RMI2,TMEM97,NIT2,RXYLT1,NUF2,ZNF267,TCF19,KTN1,APP,PRKD3,CLUAP1,ATP2A2,UTP18,GRSF1,DUT,ZCCHC2,ANAPC7,RNF19A,FAM76B,CLN6,TMEM9,GCC1,RNF169,ADCY7,ATP6V1G1,ENPP4,RNPS1,CDCA2,FKBP3,DDX17,CHCHD3,PEX5,CDC16,HIPK2,NT5C3B,MBOAT1,TICAM1,PDXK,ZBTB11,ANXA6,TMBIM4,GMCL1,UBE4A,IL21R,ETS1,WRB,PLPP5,ZNF92,PNO1,CAPN2,ADD3,SUV39H2,TPCN1,TMX1,HNRNPM,LYPLA2,MFSD12,LDHB,PPP3CA,POLK,JTB,EMP3,MTMR12,ZP3,PDE3B,CIP2A,KIF18A,CCDC6,WNT5B,MAPK6,LY75,C4orf46,SLC25A19,RGL1,PSAP,WDR76,IGBP1,FAF1,SNAPIN,COX15,AGRN,THOC1,GNPDA1,GPBP1L1,PPP1R15B,CSNK2A1,EBNA1BP2,GIT2,BIRC2,ATPAF1,DLG5,ABL2,XRCC2,ZFYVE27,MCMBP,PTPRK,CDC37,METTL1,SP3,EXOSC6,HARS,CYSTM1,GMFB,ESYT1,ANLN,RAB5B,RHEB,DPYSL3,TBC1D17,TIMM13,CDCA4,TONSL,NRM,NAGLU,ACTB,ZNF45,SINHCAF,C2CD5,TMUB1,CTCF,ASAH1,DOCK11,CRLF3,ASXL2,LRRC14,NUS1,CMTR2,SLC27A4,AFF1,MDFIC,MAML1,CYTH1,NQO2,UTP15,EIF2AK1,EIF4G2,ZDHHC3,SPATA33,MOSPD3,CDC27,SNAP23,TBPL1,PRMT7,ATP5F1A,KCTD7,NDUFA5,CYLD,UGP2,DYNLL1,COPE,HCFC1R1,ZADH2,GGPS1,RPAIN,RAD23A,ABRACL,SEC11A,PDK2,ATP6V0B,ZBTB21,STRBP,TNFAIP8,DUS4L,MRPL34,PDCD2,SAP30L,CLPTM1,RPL29,TIMP2,RPL35,BTG2,TUBGCP5,DNAJC9,FRAT2,MTMR6,NFATC2,KDM1B,ARL5B,USP36,MRPL2,ATP1A1,CLK3,MAFK,PSMD3,NDUFA11,CEP55,PLGRKT,ZNF436,DNAJC17,NCOA1,SLC25A39,ZC3HC1,ZNF146,CDC40,SMAP1,GOLIM4,GNE,SMC6,ARFIP2,NKRF,CHAC2,BZW2,WRNIP1,SS18L1,CENPM,PTGES3,CAMK2G,MLEC,ZNF202,PPWD1,FAM50B,RHOT2,NEU1,GOLGA7,PGRMC1,GLG1,FAM126A,SPCS3,RPS6KC1,UBE2C,PPCS,NDUFB6,ZDHHC8,PLXNA1,CCNB1,SLC20A1,COMMD6,ABHD14A,RIC1,POLR3K,C14orf119,UTP25,ASAP2,SNUPN,CNPY4,SPTSSA,PLCL2,TFG,SEH1L,ATG9A,ARHGAP45,PBK,MKI67,DDX20,AMDHD2,SLC17A5,GALNT7,CCNF,FOXRED1,RBM47,WDR4,SARAF,DHTKD1,TRAF5,HDAC2,PWWP2A,HSPH1,LIME1,MAPRE1,CHTF18,ADO,KIF23,SLC35B1,NOTCH2,PMF1,COPG2,JMY,NDUFAF6,FKBP1A,SLC31A1,SNX18,ATIC,CTPS1,SLC25A51,ATP6V0A2,PIKFYVE,RNF135,LPCAT1,EEF1D,TMED2,PHF10,FTL,DDX28,ZNF84,SIGMAR1,PIP4K2C,RIT1,PLEC,CYFIP2,KDM3A,SF3A2,FAS,EPRS,ZNF777,QARS,CSNK1G1,DCAF11,PPP3R1,TCOF1,NRBP1,CABLES1,DNMT3A,RWDD1,TRIP10,SF3B1,RPS6KA1,SUZ12,CAST,RAC1,GPR89A,OLA1,SNN,SDE2,GNB2,FLAD1,APLP2,KDM2A,TNPO2,CDKN1B,TALDO1,GPX4,ATP13A1,MAPRE2,RFC3,ERF,TAOK1,CUL3,SLBP,H2AFV,POLG2,GAR1,PSMB9,CENPU,DHX57,SOCS7,NSA2,HSPA4,MRPL55,JAK1,FAAP100,TBL3,GOLGA8A,SEL1L,H2AFX,B4GALT3,PDCD11,CSNK1D,ATMIN,POLQ,POU3F2,OTUD5,NCOR2,ANKRD13D,PKP4,SCAMP3,TWNK,BABAM1,CDCA3,SLC25A12,BLM,TMCC3,GTF2F1,RPL17,CRAT,AHSA1,PRC1,UPF2,COPS7B,SLC38A10,CNOT6L,CNPY3,UBE2M,IFT46,TSHZ1,ZFP64,STRIP1,DENND4C,DENND1B,WDR18,RPL8,ILF3,LRRC1,RHOT1,MARK2,TSR2,ECH1,POLR2A,PRDX1,PLD3,NUCB1,FBXO21,GNA12,C1orf131,PRDX3,PFDN4,HNRNPH3,CCZ1B,STX18,TFDP1,NAXE,KHSRP,ASNA1,CPEB2,BYSL,VPS29,DDX52,S100PBP,MIB2,ADA2,IER2,PTMS,NOP2,UBN1,NF1,DCAF15,ALKBH5,MOGS,UBE2Z,TAF6L,BECN1,MAPK14,SNAPC4,RNF103,BCAT2,MBD4,CYREN,CMSS1,METTL14,IMPAD1,RCSD1,PHTF1,SRI,KHDC4,KIF22,ZBTB22,NFU1,OGG1,TRIM14,ELOF1,COPS8,FYTTD1,TRIM8,RRM2,SOX4,ABHD5,CXXC4,UBTF,PAF1,SPATA2,PQBP1,IARS2,ATXN2L,ROCK1,GALNT10,STARD3NL,CEP170B,RPS15,PIGN,AGTRAP,CIB1,CDIP1,XPO7,SRRT,APOPT1,ZNF449,CAPZA1,GLTP,KIFAP3,BCL2,N4BP2,HP1BP3,VOPP1,ISG15,CAND1,GNAS,TSC1,RBM25,CDCA5,ZFP90,NANP,RBBP4,HNRNPDL,NIPSNAP2,ZBTB24,SMARCD1,MBD1,WASF2,MMACHC,TOMM20,IFI27L1,GNPNAT1,FAM92A,MPHOSPH8,HNRNPUL2,NSD3,CHD1,MEAF6,MIEF1,BABAM2,CCDC50,AKAP8,PARL,RPN2,CHTOP,F2R,TMEM14C,SCYL3,ABI1,HTRA2,MOSPD1,RLIM,FAM172A,ZNF500,PSMB7,NLN,WIPF1,BOLA1,ERBIN,BUD13,NDUFB1,PEF1,EIF3G,BTBD1,TAB2,CHCHD1,TULP3,WDR59,CANT1,SCARB1,GAS2,USP11,SMURF1,TSPAN5,PPP2R2D,CDS2,MAGEH1,MRPL42,EYA1,CDK2AP2,MRPS26,LETMD1,KLF13,HDDC2,RGS1,MAN1A1,FBXO5,GART,PELO,TANK,BRD7,MRPL11,SAMD4B,ZDHHC18,GTF3C6,POLR3GL,WDR81,MEN1,ZNF407,MFN2,COX8A,ZRANB2,SRSF3,MBD6,ATP6V1C1,IDH3B,TATDN1,TSC2,LACTB2,CMTM6,RBM4,ZNF275,RPL23A,CDKN2C,NAPG,USF1,DNAAF2,MECR,AP1M1,UPRT,CRY2,ECD,RNF26,MOB1A,TIPARP,LRRC59,ANKRD9,MGAT5,RHBDD2,MRPL57,BAK1,ZNF559,RHOBTB3,GABPA,NUTF2,COA7,GINS4,ARF4,KRIT1,BOLA3,AHNAK,RAD18,PDRG1,RNASEL,CHPF2,OAZ1,PDCD4,SMNDC1,NXT2,HIVEP3,CLSPN,RHOC,DHX9,PDCD7,PSMD9,HAUS2,COPB2,TFAP4,CD59,RNFT1,RBM34,RIMS3,MEGF8,EFTUD2,FBXO7,MYDGF,MRPL21,CPSF4,PHKG2,LUC7L2,SRSF11,EIF3L,MAPKAPK3,MTA2,SF3B6,ERO1A,MTFR2,USP10,ITM2A,SSR2,BCLAF1,MTX1,SFXN5,FNTA,PDLIM1,TXNDC16,CFAP20,ZNF830,MRPL3,NUP58,ALS2,FAM72A,TRIM41,KARS,GGNBP2,NQO1,POC1A,PTTG1,ANK3,TPX2,TBC1D13,DAZAP2,STMN1,GLRX3,REPS1,SH3BP1,MTA1,UBA5,CLCN6,NABP1,MICU2,INTS12,RPRD1B,CGGBP1,CPNE1,ULK3,SEC61B,POLR2L,FAM118B,KAT7,GOPC,CRNKL1,E2F3,CIRBP,RPL38,PFKFB3,GORAB,RAB1A,PPP2CA,KIF2A,ALDH3B1,CCDC14,LSM6,RNF38,DMWD,SNRPG,CENPBD1,USP13,MZT1,ZFP91,TRMT6,IP6K2,WDR5,SLC25A43,IFT27,PMVK,RRP36,NEIL2,SAPCD2,SRXN1,RPA2,PSMD2,CLIC4,PDCD10,ITGB8,COQ4,ARF5,ARHGEF1,GTF2H2,FBXL19,UTP20,MAGT1,GPS2,DBI,SSNA1,CD81,AAMDC,WDR13,FANCI,PAPOLA,CREM,FANCL,TET3,TIMM23,GLIS2,IL6ST,INTS1,POP7,SLC44A1,MTPN,ASB6,PLK1,RPP25,CELSR2,SEPT9,RBX1,APH1A,RAD51AP1,ZBED5,CKAP2L,PSMG1,UBE2V1,IL12RB1,EAF2,KRTCAP2,LUC7L,LSG1,NECAP2,ALG3,TRIM4,AGPAT2,CHD3,ZNF367,E2F4,PRPF4,KPNA2,BEND6,CLN3,DNAJC30,FAM208A,NGLY1,POT1,MYL12B,CCDC137,RMND5A,NEMP2,HJURP,PHB2,DNAJB2,NKD2,SDC2,KLC1,CDK13,COX4I1,RAB6A,DNAJB1,CNOT11,ARID1B,C1GALT1,MLX,UBE2Q2,CCP110,ZNF746,ARL6IP1,CTR9,ICE2,NIPSNAP1,ABHD2,DCAF8,ACSL3,LDB1,MAP4K3,ARMC8,NPIPA1,RBM38,IRF5,RMC1,NMT2,RPL36,HAUS8,PAXX,MBIP,ORMDL2,COX7A2L,LAMTOR4,ZDHHC7,SIL1,DTD1,UNC13C,BCCIP,SART1,TRAF7,NDUFAF2,TOR1AIP1,ZNF416,LAGE3,ZFYVE21,RRAGC,ZNF121,OIP5,NRF1,ABRAXAS2,WDR44,PIN1,PPME1,RPAP1,TOP1MT,LMAN1,AHCYL1,STRAP,SPSB3,ZNF583,SNX25,ARHGAP17,POLR2G,ZNF780B,PPT1,NUP155,DCLRE1C,MRPS14,RHBDF2,AFDN,SUGP1,RBL1,FASTK,UBXN2B,STK38,AP1S1,SPRYD4,SLC22A23,H3F3A,CHID1,SMAD4,RAD51D,SLC30A9,NADSYN1,CMAS,UNK,AGO2,HMGN3,NCAPG,SCYL2,FZD6,HERC3,GTPBP3,CTSS,ORC3,YTHDC1,ACP2,CSRP1,HMGN5,PRKDC,ABCF2,TUFM,RANGAP1,PNPLA8,HAGH,API5,ZFR,SEC23IP,E2F1,USP20,TMEM219,RBPJ,MAX,PDCD6IP,LUZP1,ADAM10,CXXC1,TSC22D3,AP3M2,CUL1,GYG1,NANS,OAT,MYEF2,ANKRD26,PA2G4,MTFR1L,NOL11,FIZ1,ZNF200,AP2B1,FBXW2,MARCH2,SLC26A2,SRSF10,SRP72,KLF10,LACTB,SUPT20H,CBFB,RFC2,RAB2B,PRIM1,MAP3K4,HHEX,BRD2,RPS14,LUC7L3,MAP4,MRPL27,BTF3,PTPDC1,SLF1,CCDC59,NMD3,PTOV1,COX5B,DNAJC5,SCOC,DHPS,POLR2K,ANKH,VAV2,PRKAA1,GSPT2,DLGAP4,TATDN3,PXMP2,PRPF39,PSEN1,ZNF79,PDXDC1,VPS25,NDUFS7,YY1AP1,C12orf10,FAM192A,RPN1,LHX8,ARPC5,ZNRF2,DAPK1,TPST1,PIK3IP1,CYC1,MRM3,SOCS5,FDFT1,GID8,PIGT,CPQ,WDR1,EMB,ZNF574,C1orf35,EXOSC9,ARID1A,PTTG1IP,FXR1,GOSR1,MAP2K2,TWISTNB,AKAP1,XRCC5,HMGN2,PI4K2A,SEC31A,CAT,DERL1,HSPBP1,MTHFD2,CEBPG,ARAP1,USP32,FAM83D,CABIN1,SMPD4,GPI,CYTIP,TP53RK,REPS2,RAB11B,UROD,SLC39A13,POMP,BCL2L1,NUDT19,DECR1,RALB,SIAH1,LPIN2,ADCY9,SOCS6,MRPS27,TTC3,RNASEH2A,CFL1,ANKLE2,CDC123,VDAC2,EDF1,ERC1,EML4,ANKZF1,ZNF282,RAD51C,DSN1,DDOST,HINT1,DGCR8,RAB24,SAFB,FTSJ1,NCLN,BEND3,EYA2,DYNC1LI2,B4GALT5,SLC41A1,MANBA,TKT,FAM76A,CBLL1,ARGLU1,LANCL1,POFUT1,HEATR5B,HLA-A,EBP,RFWD3,NDUFA2,FUT8,PTPN11,MRPL54,FEM1B,RPL19,CNN2,NDUFA3,MTX2,MSH6,PDLIM2,LONRF3,RFXANK,FBXO9,GUF1,SPPL2B,RPL32,ZHX1,OAZ2,NDUFS5,WDR91,GPR89B,HIGD2A,ZBED3,RORB,POLA2,ZNF76,MTX3,COPA,KMT2E,UQCR10,HMGXB3,ABCB10,COMMD5,MAP1LC3B,ATP5PF,DST,SIVA1,RAB35,GPATCH1,TCEA1,CARMIL1,DRAM2,DEAF1,TRAPPC13,SNRNP200,NCK1,LAP3,VHL,SREK1,ARHGDIB,PITPNB,HSPB11,BRWD1,PPM1G,SH3GLB2,CRCP,BAZ1B,CAB39,STK11,CLU,CHEK2,MRPL13,CHPT1,DCAF5,CAPN1,UBE2D3,NSMCE4A,PPP1R12A,ZCCHC8,GORASP1,UBXN1,NACA,EPN1,PCSK7,RPL15,THRAP3,TTF1,QSOX2,PRPF18,NUP205,CHKA,DTL,MED10,PYURF,ORAI1,TENM3,ZRANB1,MCPH1,SLC12A2,ATP6V0D1,CSNK1G3,ATP5IF1,CREG1,NUDT4,ERLIN1,RPL6,VKORC1,SLTM,EVC2,KLHL15,SIAH2,SLC16A1,DNPH1,EHD4,SNRNP70,C11orf1,APOL2,N4BP2L2,SNX27,CHMP2A,CORO7,FEZ2,PMS2,UCK2,UCK1,CLCC1,EXT2,MXD1,USP5,HNRNPA2B1,SAP130,NVL,PPP6C,CYB5R1,UTP4,ZNF770,EBAG9,RNF25,PCGF6,FAM72B,PON2,VPS26C,HNRNPR,STAT6,HPS5,MAPK1,TMEM33,PDF,NAT14,DNAJC2,TRIP12,SHPRH,SCYL1,VPS45,MYO9B,GFM2,SPPL2A,FASTKD3,FGFR3,MZT2A,GRK2,PPIG,KMT5A,ZDHHC13,NABP2,H2AFY,ATG13,NDUFS8,FBL,FRMD8,SLC35A1,MICAL3,TGFB1,B3GALT6,ELOVL5,PPP1R9B,HEMK1,TIMMDC1,HELB,PSPC1,MIER1,NADK2,NDRG3,CDK11A,MTMR3,ACAT1,KMT2B,CENPT,PLOD3,RAB3IL1,ZSWIM6,RAB14,ADD1,MRPS15,KDM4A,XIAP,DHX8,GLUD1,ANKRD23,PABPC4,CALM2,CDK5,PSMD1,NEK6,NSRP1,RABGAP1L,SRSF4,FNIP2,SPATC1L,KCNAB2,PCBP2,MLST8,PLK3,ZNF672,MRPL43,HSDL1,TOPORS,MCL1,SMC2,PPFIA3,ICMT,SLC50A1,STOML2,LIMK1,ZNF689,PRDX5,VIPAS39,ATE1,MLYCD,ATP6V0C,ST3GAL2,FBXL3,TFDP2,E2F2,PFKP,AAAS,DDX42,SSRP1,MRPL9,MRPS2,STRN4,TOP2B,ZNRF3,TMED3,DDRGK1,RAVER2,GNS,INTS7,INPP5A,MCM5,PHF14,ZNF326,RTCB,UBE2QL1,NAGPA,TIMM8B,CYFIP1,ETV3,TSPYL4,TSPAN31,DHX29,TEX10,MAN1B1,RPS10,CBFA2T2,ABCF1,RHOB,PTPRF,SCARB2,OSBPL11,CCDC86,DUSP3,CSK,SLAIN1,MDH1,HEXA,SGF29,RNF139,SNX14,ZNF296,FAM208B,TRERF1,UBR2,CHD1L,ACTR3,WDTC1,MYH9,CREBL2,NIPA2,PRKACA,SAFB2,ANKIB1,STAM,RAB21,SP100,ZKSCAN1,DDA1,NUP107,ANKRD13C,MAVS,CEP63,RBM15,ATF2,DCTN1,SHOC2,PSRC1,INTS13,MAP4K4,WBP2,ATP6V0A1,NUSAP1,DNAJA1,NDUFA7,TAZ,TAF2,SEC61A1,WDR7,RPLP1,RBMS1,FUS,GEN1,LRP8,COIL,LRCH1,GALK1,ZNF786,RPS2,SESTD1,TRAK1,JMJD6,SIKE1,AKT1S1,KRI1,FBXO3,ERH,GATC,NDUFB4,PPP1R8,PRDM4,GTSE1,GEMIN6,DCP1A,SGCB,S100A6,IMPA2,NUDC,PDPK1,MOB4,TK1,GUK1,TNFAIP3,GALC,ZNF512,MRPS10,DDX39A,RPA1,ZNF180,ZNF862,KEAP1,POLE,TATDN2,PITX1,CAPN7,LRPPRC,PML,HMGB2,USF2,ANAPC4,SRM,DDX47,MCCC1,CDC42SE2,S1PR2,CDIPT,SEC16A,KCMF1,SSR1,LIN9,PCNA,ZNF639,TRMU,PIK3R2,ETV6,PPCDC,TXLNA,MYBL1,MRPL32,CCAR1,ABCC5,PBXIP1,BAZ2A,TLK1,MRPL12,EZR,LRP5,BRCA1,PRKRA,STX16,EPB41,OPTN,SEPT1,SOCS4,QRSL1,PIEZO1,DHFR2,OSGEPL1,GLCCI1,NUDT11,NAA60,GEMIN7,SEPHS2,LZTR1,RACGAP1,PPP3CB,B4GALT4,RLF,RAPGEF6,SNRNP25,RB1,VASP,MED8,TIGAR,VMP1,PPIL2,MEA1,TIMELESS,ALDH18A1,TMEM8A,ABCC1,PREB,TRAPPC9,AACS,MEMO1,KRAS,RTF1,UBE4B,NFATC2IP,LY6E,ARPC1A,ZNF174,PSMC4,GOLGA4,PALB2,SYNCRIP,NIPA1,TIGD2,RNF114,FOXM1,MRPL39,XAB2,SUMO2,DUSP22,COMMD8,RPL11,CSDE1,MDM2,CORO1A,MINPP1,POC5,DVL2,GM2A,PSMA8,COQ10B,CPOX,TIGD5,SLC26A6,PRPF3,TXNL4A,RPSA,SRSF1,DNAJC10,SCAP,ZNF700,TIMM17A,TOMM6,LTA4H,AP2S1,INTS2,CTDP1,MIF4GD,CDT1,ARID5A,SUMF1,GGA2,AP3S1,CSNK1A1,RMI1,TFRC,PTPN2,IRF4,STARD9,GSTK1,NDUFV1,SLC1A4,CWC27,SLC35B4,DDX31,ABCD1,RPAP3,CNTN5,SNX2,ZMYM5,BORA,CHCHD6,KPNA4,CDKN2AIPNL,FBXO41,BIRC5,TFE3,SNAP29,CDCA7L,PKD2,ACADM,CHMP7,SAT2,GCSH,ZNF496,TMEM109,TAP1,YTHDF3,NHLRC3,IKBIP,KIFC1,DBNDD1,CYB5RL,PARPBP,CDC25B,MAST2,DNMT1,NOL12,ORAI2,USO1,AKT2,NOL8,GNG7,ELOA,MRNIP,AURKB,MCFD2,SLC25A5,ZFAND5,MAK16,STT3A,TMED10,PSMD8,EIF2D,ITGB1,PTPN7,UQCRH,RRS1,ARRB2,RTN3,SVIP,DDX58,WSB2,PPIB,MUT,GMFG,HLA-E,NDUFA4,MAN2B1,METTL3,CFLAR,NDUFS4,RNF121,MEX3C,KLF16,HDAC7,DAD1,BDH1,PCYT2,GNAI2,ANKHD1,TERF2,MORC3,NOA1,KCTD20,SEPT8,DCTD,PKM,TOMM40,PATL1,PSMB3,ADSS,SERTAD2,SERF2,ZFP92,NSF,DCK,ERGIC3,ACLY,LPCAT4,VCPIP1,YY1,PPP6R2,MAP3K5,PPP6R3,RNF14,CDK2,ZC3HAV1,SYS1,ZBTB37,URB2,EIF3D,MAGED1,KLHL18,ADPGK,SLC25A44,AP1B1,SDHA,PAIP2,PHC2,CRKL,MOAP1,TERF2IP,CYHR1,ZNF75D,SHC1,UCHL5,NAA35,TMBIM1,MRM2,CCT2,CDKN2AIP,MKLN1,HMGN4,LYRM1,GALK2,CDC23,SHCBP1,AP4E1,PRDM11,VEZF1,PPP2R5A,GUCY1B1,STAT1,PPA2,TRIM32,RHEBL1,R3HCC1L,TCF3,MRI1,BRAP,AGPAT3,MYNN,SDF2L1,SPR,RAB11A,REEP5,FOXO3,MAD2L2,PIP5K1C,RBM17,MAT2B,PTEN,CENPJ,TAGLN2,OSTC,CREB1,MAP3K14,PACS2,NCOA2,SMC4,RNASEH2C,NEK7,NET1,PARP4,TBRG4,ANAPC2,RPL27A,YIF1A,SGSH,HGS,ATP5MC3,TTLL4,SLC38A7,MFAP1,CCDC69,BRWD3,ESYT2,SKA3,NPHP4,HNRNPAB,PLXNC1,ST13,DNAJC24,ZNF107,KIF2C,SLC29A1,AGFG1,SIRT2,FKBP2,USP48,UBQLN2,SNRPD3,CUTC,EDC3,UBLCP1,ZNF804A,RAP1A,THADA,EIF4A3,AP3S2,ATG3,DPYSL2,PPP1R12C,AKR1B1,NDUFB9,JOSD1,RP2,TTC4,TECR,ARID4A,FGFR1OP2,TIMM50,TDP1,DPM1,FOPNL,SLC16A7,WDR82,SLC25A22,STK17B,DHX15,CHAF1A,GEMIN5,TIMM29,COPS6,SASS6,RPS26,PSMC1,SLC12A7,TBC1D12,TM9SF4,ZNF768,UFC1,MED13L,TIA1,MEF2A,EPHX2,PITHD1,RHBDD1,NFATC3,BANF1,BUD31,ZNF335,YBX1,KNTC1,ACAD8,UBE3C,ZNF189,ALDH9A1,KDELR1,TSTA3,CIC,OXR1,PSMA1,SEPT7,NAP1L1,NSMF,ODF2,EXOC4,TRMT10B,NUP62,PITPNA,NAA20,PTDSS1,MZT2B,PDSS2,TMEM106C,IMMT,ASH1L,CHERP,WDYHV1,PLAGL2,CHKB,IRF3,TWF2,PAIP1,ANKRD28,ANKLE1,FARSA,SAR1A,APOOL,PDIA6,ACSL5,CGAS,DMAC2,TOR1AIP2,AZI2,GFER,RAD54B,DAP3,ZNF317,GADD45B,AKNA,REEP4,CBX4,MIF,KIF3B,GOLPH3L,SH2D3A,CASP6,TOR3A,SRGN,DBF4,TIMM21,MFSD10,SAC3D1,CTNNBL1,YIF1B,CLDND1,TTC17,SLC25A1,GINS1,PAQR6,CSNK1G2,TELO2,ADAM17,HMGN1,NASP,ASPM,PRKAR1B,ATP5MF,SYMPK,TARS,SNRPA,MAPK3,HSPA1B,CNOT9,HLA-B,ATAD2,PLAA,ZNF330,OSBPL8,KBTBD7,PREPL |
| 1.139e-41 | -94.28 | CAIRO_HEPATOBLASTOMA_CLASSES_UP | MSigDB lists | CAIRO_HEPATOBLASTOMA_CLASSES_UP | 568 | 215 | 17377 | 2626 |
LYRM4,ST13,CSNK2A1,PTP4A3,AGFG1,KIF2C,CCNB1,RBM4,PABPC4,ZNF696,FANCI,NUP210,NOL11,EIF4A3,THAP4,RAB4A,POP7,AP2B1,KIF22,NUP153,TCEA1,LRRC59,DNMT1,MLST8,SRP72,PLK1,TDP1,SNRNP200,AATF,SEPT9,RBX1,PBK,SNRPB,RAD51AP1,MKI67,MRPL12,KIF15,RRM2,PSMG1,CDC6,AURKB,SMC2,CCNF,MCM2,RFC2,ODC1,CLNS1A,GINS4,CHAF1A,STOML2,CDCA4,KIF18B,NIP7,U2SURP,C1orf109,PQBP1,UQCRH,KPNA2,CHEK2,RRS1,HDAC2,PDCD4,SSRP1,DDX42,MAPRE1,HJURP,SEC61G,PHB2,CENPF,RRM1,KIF23,RPL15,CHCHD2,FAM136A,XPO7,MYL6B,NUP205,SPAG5,DTL,DDX56,EIF2S2,ATIC,MSH2,TIMELESS,YBX1,AHCY,KNTC1,CYC1,ALDH18A1,NUP85,PPA1,EEF1D,KDELR1,EIF3L,RB1CC1,MAN1B1,ACSL3,AMD1,RPL6,GTPBP4,USP10,FXR1,XRCC5,RPL36,EPRS,SLCO4A1,FNTA,PCM1,CDC27,QARS,ODF2,ERGIC3,ACLY,CNOT6,YWHAZ,RUVBL2,CCNB2,PTDSS1,BCCIP,ZNF207,KARS,TOMM20,DNMT3A,CKLF,WDYHV1,OLA1,TPX2,TMEM97,SMARCA4,COMMD8,RPL11,OIP5,SAP130,FARSA,CCNA2,IARS,UTP18,MTA1,KIF14,MRPS27,RPN2,RNASEH2A,MAVS,PDIA6,HTRA2,CPNE1,CCT2,POLR2D,VDAC2,DNAJC9,NUSAP1,TXNL4A,TRIM28,RPS9,EIF3H,SRSF1,SUPT16H,DNAJC10,DDOST,CERS6,HNRNPR,NCLN,PDCD11,LTA4H,COIL,MIF,MCM10,CDT1,DBF4,CDCA8,NCAPG,BZW2,TFRC,PNO1,FBXO5,GTF2F1,RFWD3,HOMER1,GART,HUWE1,PRC1,GTSE1,RPL19,FBL,MSH6,SMC4,GINS1,ASPM,PRKDC,KIAA0930,ABCF2,MRS2,ILF3,RPL8,RFXANK,TBRG4,ADSL,LRRC1,BORA,DDX39A,KIF11,ZFR,CBX3,UTP20,TPD52L2,KIF18A,SEC23IP,BIRC5,LRPPRC,HMGB2,TAF12,UBE2C,BYSL,GCSH,IPO4 |
| 1.265e-41 | -94.17 | ELAVL1 (ELAV like RNA binding protein 1) | protein interactions | 1994 | 1780 | 501 | 17029 | 2761 |
TMED7,HECA,PDCD6IP,TSC22D3,TMEM41B,XIAP,AGPAT1,CUL1,GLUD1,IKBIP,EIF1B,SLC20A1,CMTM6,PABPC4,SLC25A37,EEF2K,NAPG,USF1,ASAP2,CIPC,RAD23B,ZNF200,CISD2,TAF5L,MARCH2,SPTSSA,SENP1,ZNF800,PCBP2,SEH1L,CDC5L,NRAS,OSBP2,LACTB,HNRNPF,NUTF2,ICMT,SLC25A5,CBFB,MAK16,SLC50A1,RAB22A,RAB2B,ARF4,PLEKHF2,STOML2,ANKRD10,SMAD2,BRD2,RBM47,STT3A,LIMK1,ITGB1,E2F2,TRAF5,LONP2,ZMAT3,PDCD4,SMNDC1,HDAC2,NXT2,WSB2,EWSR1,MUM1,VAV2,PRKAA1,C16orf87,B4GALT1,PDCD7,PSMD9,COPG2,LMNA,NPLOC4,FAM192A,TFAP4,FKBP1A,RPN1,MEX3C,ARPC5,ZNRF2,ATP6V0A2,FOXN2,TNPO3,OSTF1,LPCAT1,NSUN4,PABPC1,LUC7L2,TMED2,TERF2,GID8,EIF5A,PRIM2,C16orf72,TSPAN31,MTA2,ZMYND11,TYW1,RDH10,PIP4K2C,DCTD,ARID1A,SRSF5,CAPZA2,FXR1,ELK1,PATL1,SF3A2,MTR,RHOB,TWISTNB,SERTAD2,OSBPL11,MTHFD2,KPNA1,POLR2J,CSK,DUSP3,DCK,SETD3,LPCAT4,CEBPG,PPP3R1,CNOT6,YY1,PPP6R3,TMEM159,ZC3HAV1,NUDT3,FAM72D,TP53RK,TRERF1,IVNS1ABP,SUZ12,CAST,TMEM97,C5orf30,CREBL2,SLC25A44,DAZAP2,LCLAT1,RCOR3,SDHA,SDE2,CPNE3,PAIP2,CRKL,RAB21,APLP2,CLUAP1,KDM2A,ATP2A2,MTMR4,MTA1,DUT,DDA1,MRPS27,NABP1,CDKN1B,TNPO2,SEPT11,FAM76B,RBM15,GPD1L,ARL5A,CDK12,CGGBP1,SZRD1,PDCL3,ERMP1,BRD4,MKLN1,VDAC2,E2F3,CIRBP,CUL3,RNPS1,POLR2D,PFKFB3,LRRC8A,NUSAP1,CDC23,RAB1A,AP4E1,H2AFV,EML4,GIGYF1,MAT2A,DDX17,SUPT16H,TAF2,VEZF1,CCDC14,SAFB,CORO1C,CAMKMT,RWDD4,RNF38,H2AFX,EFCAB14,PDXK,NKAPD1,DYNC1LI2,TUBB,ADAM23,DEPDC1,B4GALT5,SLC41A1,ZFP91,SRSF6,MECP2,TCF3,FAM76A,MYNN,ARGLU1,GMCL1,UBE4A,SLC25A43,ETS1,RAB11A,FOXO3,HMG20A,CCDC28A,HEATR5B,NEIL2,TUT4,EBP,RBM17,MAT2B,RFWD3,RPA2,CCNK,ERH,PTEN,ARF5,BTF3L4,PTPN11,GEMIN6,COPS7B,UPF2,CNN2,NAP1L4,CITED2,TMX1,TTPAL,STAU1,TNFAIP3,NET1,MRPS10,LRRC1,KIF11,TTC33,POLR2A,RPA1,CBX3,FBXO21,TMEM127,ZHX1,CCDC6,TMEM268,OAZ2,TFDP1,MAPK6,KHSRP,C4orf46,HMGB2,DUSP11,YWHAH,WDR45B,S100PBP,ZBED3,UBL3,ZNF76,PIGM,COX15,IER2,UBE2E2,ST13,KMT2E,GPBP1L1,FLYWCH2,ALKBH5,PTP4A3,CSNK2A1,ABCB10,CDC42SE2,SNRPD3,UBQLN2,TRIM65,ZNF696,SSR1,PAPOLA,RAB8A,RAP1A,CDC42,DPYSL2,ZNHIT6,ETV6,SLC44A1,TXLNA,JOSD1,CNNM3,ASB6,MTPN,FGFR1OP2,DRAM2,CARM1,RYBP,EXOSC6,TRIM8,RBX1,APH1A,FOPNL,VHL,TLK1,TMEM216,GMFB,EZR,SREK1,RRM2,SUMF2,PITPNB,KMT2C,SOX4,RAB5B,TRAM2,CDCA4,TIMM13,NIP7,SPATA2,ACTB,CHEK2,CLN3,CHPT1,FAM208A,SINHCAF,C2CD5,FUBP1,STARD3NL,UBE2D3,RPS15,PARP12,PIGN,PPP1R12A,PPP1R2,TM9SF4,SDC2,LAMTOR3,PCSK7,PROSER3,PPP3CB,RAB6A,PM20D2,CNOT11,CRLF3,PITHD1,SUB1,UBE2Q2,CCP110,VMP1,ZNF746,ARL6IP1,CAPZA1,ICE2,RBM3,GLTP,GLE1,UBE3C,CSNK1G3,AMD1,KRAS,UBE4B,TMEM241,SEPT7,ARPC1A,APPL1,ZDHHC3,ANKRD46,ISG15,CAND1,NAP1L1,UAP1,RBM25,SNAP23,ODF2,PRPS2,COX7A2L,TBPL1,RBBP4,TMEM14A,HNRNPDL,PTDSS1,PDSS2,TOB1,ADNP2,TCF12,SNX27,CYLD,TOMM20,SUMO2,TOR1AIP1,TM9SF3,PCBP1,LYN,ZADH2,CHD1,MEAF6,C2orf68,CSDE1,HNRNPA2B1,RRN3,BRPF3,SAR1A,WDR44,ABRAXAS2,AKAP8,PPP6C,RPAP1,TARDBP,BCAP29,SCAMP4,LMAN1,AHCYL1,CHTOP,ZNF770,DVL2,GM2A,CHP1,KDM3B,FAM172A,CGAS,COQ10B,RAB7A,CPOX,PCGF6,METTL2A,MTMR6,WIPF1,PRPF3,HERPUD2,VDAC1,TOLLIP,MBD3,FANCE,SRSF1,GLOD4,TMEM101,LTA4H,SLC30A9,GOLIM4,GOLPH3L,AGO2,GNE,TMX3,CDCA8,CHIC2,DCUN1D4,AP3S1,CSNK1A1,BZW2,FZD6,XPR1,DNAJB9,GART,KMT5A,ANP32A,ARHGEF2,ABCD1,LDLRAD3,C12orf75,STAT3,FRMD8,NIPAL3,SAMD4B,ELOVL5,RPRD1A,MLEC,FAM49B,PRKDC,BTAF1,MIER1,ATP2C1,NADK2,NDRG3,API5,ZFR,HSPA1B,CNOT9,KPNA4,BIRC5,CDCA7L,BBX,CTBS,RBPJ,TAF12,MBD6,SRSF3,PREPL,GUCD1,UBE2C,SLF2 |
| 7.102e-41 | -92.45 | TRIM25 (tripartite motif containing 25) | protein interactions | 7706 | 2254 | 596 | 17029 | 2761 |
TMED7,ZBTB10,ADD1,PIGQ,AGPAT1,DHX8,PPP1R16B,PABPC4,FBXO22,SMIM13,RPL23A,PSMD1,THAP4,RAD23B,PDS5B,DNM2,MGAT5,FTSJ3,MLST8,USP34,RHOBTB3,HNRNPF,PPFIA3,NUTF2,ARMH3,DIDO1,ICMT,MCM2,AHNAK,RPS27A,AXIN1,OGT,ATE1,ST3GAL2,OAZ1,LONP2,PFKP,DDX42,HIVEP3,KIAA0100,GGA1,TRIO,STRN4,DHX9,CERK,LMNA,DDX56,EIF2S2,INTS7,EFTUD2,FBXO7,ZNF326,RTCB,TNPO3,PABPC1,LUC7L2,SRSF11,CYFIP1,RB1CC1,RPS10,GTPBP4,ABCF1,SFXN5,MATR3,PTPRF,MAGED2,SETD3,MDH1,MRPL3,RHOG,EXOC3,NQO1,MYH9,DAZAP2,GLRX3,APP,KTN1,KIAA1147,RAB21,PRKD3,FBXL6,ATP2A2,UTP18,MTA1,GRSF1,NUP107,ANKRD13C,ANAPC7,MAVS,CLN6,RPRD1B,TMEM9,ARL5A,SZRD1,DCTN1,CPNE1,SHOC2,ERMP1,POLR2L,MAP4K4,E2F3,RPL38,PFKFB3,HTATIP2,DNAJA1,MAT2A,PPP2CA,CHCHD3,HIPK2,RPLP1,RNF38,TICAM1,FUS,DMWD,PPP5C,LRP8,RPS2,ZNF445,ANXA6,CCM2,AKT1S1,IP6K2,SLC25A43,SAPCD2,GOLM1,PSMD2,CLIC4,HUWE1,DCP1A,ANXA5,KANSL2,NAP1L4,S100A6,IMPA2,NUDC,LDHB,SPTAN1,DDX24,LDHA,ZP3,PICALM,RPA1,UTP20,CCDC6,MAPK6,LRPPRC,PML,CD81,FAF1,COX15,DDX47,GPBP1L1,WDR13,CDC42SE2,SND1,KCMF1,BIRC2,FANCI,ABL2,PCNA,GLIS2,IL6ST,SLC44A1,TXLNA,RYBP,PLK1,SNRPB,EZR,LNX2,LRP5,UBE2V1,BRCA1,ANLN,STX16,RAB5B,RHEB,EPB41,AGPAT2,CHD3,KPNA2,PIEZO1,FAM208A,MYL12B,GEMIN7,FUBP1,PARP12,KLC1,CTCF,CDK13,RAB6A,CRLF3,ASXL2,RAPGEF6,ARID1B,TNS3,SUB1,VASP,ZNF746,SLC27A4,AHDC1,AFF1,ABCC1,AACS,ACSL3,UBE4B,LY6E,ARPC1A,NPIPA1,RPL36,GALNT2,SYNCRIP,ORMDL2,COX7A2L,USP7,KCTD7,SART1,TRAF7,RPLP2,FOXM1,ARID2,FAM207A,SLC2A1,COPE,TM9SF3,PCBP1,LYN,GGPS1,RPL11,RAD23A,CSDE1,MDM2,PPME1,TARDBP,SPIDR,SPSB3,PRPF19,CLPTM1,CLCN3,RPL35,TIMP2,RAB7A,ANKRD33B,NUP155,RPSA,USP36,AFDN,DHX16,CLK3,TIMM17A,STK38,FASTK,AP1S1,XRCC3,FAU,USP53,SMAD4,PARD3,PDAP1,AGO2,CSNK1A1,TFRC,STARD9,NDUFV1,ABCD1,POLR1B,PTGES3,MLEC,PRKDC,BTAF1,ABCF2,RANGAP1,ARHGEF12,API5,RHOT2,ZFR,DDX23,TPD52L2,PDCD6,BBX,PGRMC1,SPCS3,NR2F2,PGAM1,HIPK3,NUP188,MAX,LUZP1,PRKCSH,ADAM10,TMEM109,USP39,SLC20A1,RIC1,RNASEK,AP2B1,TAF5L,TFG,SPTSSA,SRP72,OSBP2,DDX20,USP22,CCNF,SLC25A5,RFC2,CLNS1A,IWS1,MKNK1,RBM47,TMED10,PSMD8,RPS14,WDR4,ZNF598,RTN3,DDX58,PWWP2A,C9orf78,DNAJC5,ANKH,VAV2,DLGAP4,B4GALT1,PMF1,TMEM165,PDXDC1,NPLOC4,YY1AP1,NDUFS7,RNF121,SLC31A1,KLF16,LRRC8D,ARPC5,PPP4R1,MSH2,CTPS1,PIKFYVE,TNRC18,LPCAT1,ANKHD1,EEF1D,MORC3,SOCS5,PIGT,WDR1,KCTD20,RPS24,CAPZA2,ARID1A,PKM,PTTG1IP,MAP2K2,XRCC5,ADSS,DERL1,SEC31A,SERTAD2,RBMX,ERGIC3,ACLY,PPP3R1,ARAP1,USP32,TCOF1,SMPD4,PPP6R2,YY1,PPP6R3,CABLES1,ZC3HAV1,DNMT3A,RAF1,SUZ12,EIF3D,KLHL18,ADPGK,AP1B1,SNN,CD320,PAIP2,SPINDOC,APLP2,KDM2A,MTMR4,RALB,RNASEH2A,TALDO1,ILKAP,GPX4,ANKLE2,BRD4,MKLN1,CDC123,PKMYT1,EDF1,ASB13,H2AFV,TRIM28,ERC1,SUPT16H,RAD51C,HSPA4,PPP2R5A,HINT1,CERS6,SEL1L,ATF6,B4GALT3,CSNK1D,OTUD5,NCOR2,NDUFS1,PKP4,SCAMP3,MANBA,B4GALT5,MRI1,BABAM1,SECISBP2,LANCL1,HMG20A,MAD2L2,SLC25A36,GTF2F1,CCNK,ELP5,RPL17,PRC1,PTPN11,FEM1B,RPL19,TAGLN2,CNPY3,NCOA2,MSH6,SMC4,NEK7,RPL8,ILF3,TBRG4,ADSL,OTUD3,RPL27A,COMMD4,KLF6,PRDX1,INF2,RPL32,HNRNPH3,OAZ2,DDX5,WDR91,DDB1,ESYT2,CCNC,PTMS,NAT9,HNRNPAB,KMT2E,ALKBH5,SLC29A1,AGFG1,SNRPD3,BRIX1,MAPK14,CUTC,EDC3,SF3B2,BCAT2,DST,RAP1A,CMSS1,AP3S2,PHTF1,KHDC4,NDUFB9,TTC4,SLC35C2,CNNM3,TIMM50,SRPK2,TRIM8,LRBA,RRM2,KMT2C,RPL37,UBTF,STK11,VPS4A,GALNT10,RPS26,DCAF5,SLC12A7,UBE2D3,RPS15,TM9SF4,AGTRAP,CDIP1,MED13L,RPL15,THRAP3,XPO7,QSOX2,NUP205,YBX1,UBE3C,CSNK1G3,HP1BP3,ERLIN1,RPL6,TMEM241,ISG15,CAND1,GNAS,NAP1L1,UAP1,KLHL15,CDCA5,EXOC4,SLC16A1,YWHAZ,RBBP4,PTDSS1,MZT2B,APOL2,TCF12,WASF2,MMACHC,SNX27,TOMM20,FEZ2,CHERP,MDH2,HNRNPUL2,UCK2,SMARCA4,IRF3,USP5,ANKRD28,HNRNPA2B1,UBXN2A,IARS,CS,SCAMP4,UTP4,HPDL,PSMB7,PCGF6,TOR1AIP2,GLO1,OGDH,RPS9,BTBD1,PON2,HNRNPR,HPS5,ANP32E,FKBP5,TMEM101,SCARB1,USP11,BRD9,MAPK1,TSPAN5,TMEM33,SHLD2,MYO9B,DCUN1D4,XPR1,KIF5B,RRBP1,H2AFY,YIF1B,STAT3,MYO5A,MICAL3,TGFB1,PPP1R9B,DCAF6,FAM49B,PRKAR1B,RCOR1,RFFL,NDRG3,TARS,HSPA1B,MTMR3,UPF1,ATAD2,ZC3H7B,SRSF3,CENPT,ZMIZ1,PLOD3,NXPE3 |
| 1.000e-40 | -92.10 | GO_MITOTIC_CELL_CYCLE | MSigDB lists | GO_MITOTIC_CELL_CYCLE | 725 | 251 | 17377 | 2626 |
POLA2,FGFR1OP,SKA3,GPR132,NUP188,PDCD6IP,XIAP,ENSA,CSNK2A1,CUL1,SIRT2,KIF2C,CNTROB,CCNB1,UBE2I,BECN1,BIRC2,MIS12,FANCI,KIFC1,CALM2,CDKN2C,RAB8A,PCNA,PSMD1,NUP210,NEK6,XRCC2,PDS5B,DNM2,KIF22,NUP153,CDC25B,MCMBP,SEH1L,CARM1,CDC5L,PLK3,PLK1,PBK,NSUN2,KIF15,RRM2,CDC6,AURKB,SMC2,PBRM1,SOX4,CCNF,ANLN,MCM2,OPTN,PRIM1,KIF18B,RPS27A,PSMD8,E2F4,MAP4,ITGB1,ZNF268,VPS4A,CHEK2,RRS1,TFDP2,PSMC1,AAAS,MAPRE1,PPP1R12A,CLSPN,GORASP1,CENPF,CIB1,RRM1,KIF23,RACGAP1,TOP2B,HAUS4,PMF1,CRLF3,PSMD9,HAUS2,LMNA,NUP205,SPAG5,CNOT3,RB1,SMC3,CCP110,SNX18,MCM5,BANF1,MSH2,TIMELESS,FBXL7,KNTC1,NUP85,PRIM2,MYBL2,PSMA1,SEPT7,PSMB3,RBM38,PSMC4,MASTL,HAUS8,PCM1,CDC27,GOLGA2,ODF2,CDCA5,FAM83D,VCPIP1,NUP62,CNOT6,NDE1,ZNF830,CDK2,CCNB2,CDKN2A,ZNF207,CHMP2A,DNMT3A,FOXM1,DYNLL1,ANK3,PTTG1,TPX2,SMARCA4,NUF2,BCL2L1,ORC1,PRKACA,STMN1,OIP5,MDM2,PSMA6,CCNA2,KIF14,AKAP8,NUP107,PPP6C,CDKN1B,ANAPC7,CEP63,ATF2,DCTN1,ANKLE2,MAPRE2,PSRC1,BRD4,BIRC3,BTG2,PSMB7,CUL3,TUBGCP5,NUSAP1,CDCA2,NUP155,PKMYT1,AZI2,CDC23,RAB1A,CHMP2B,PSMB9,TXNL4A,EML4,TAF2,PPP2CA,KIF2A,CDC16,CHMP4A,DSN1,PSMD3,NSMCE2,CEP55,CHMP4B,PPP5C,REEP4,PPP2R2D,CSNK1D,ZC3HC1,TUBB,KIF3B,CTDP1,MCM10,KLHL21,EYA1,RAE1,BABAM1,CDT1,DCTN2,DBF4,CDCA3,CDCA8,NUP54,BLM,CDK11B,CSNK1A1,NCAPG,RAB11A,TUBGCP2,MAD2L2,FBXO5,SAC3D1,RPA2,CCNK,RFWD3,PSMD2,PTEN,CENPJ,PRC1,NAA50,PTPN11,GTSE1,ARHGEF2,CNOT6L,ORC3,CAMK2G,SMC4,NUDC,GINS1,TGFB1,PPP3CA,RHOA,ASPM,PRKDC,JTB,ANAPC2,WDR81,MEN1,BORA,KIF11,CDK11A,RPA1,KIF18A,NEK1,POLE,BIRC5,TFDP1,PML,E2F1,SSNA1,CENPT,WDR62,UBE2C,CHMP7,ESPL1,HRAS,TERF1,SSSCA1,ANAPC4 |
| 1.031e-40 | -92.07 | intracellular non-membrane-bounded organelle | cellular component | GO:0043232 | 4138 | 891 | 18223 | 2701 |
FGFR1OP,ADD1,KDM4A,MRPS15,CNTROB,ANKRD23,RBM4,FBXO22,PABPC4,MIS12,RPL23A,CDK5,CALM2,USF1,NEK6,PDS5B,DNM2,NUP153,MOB1A,ZNRD1,SPATC1L,LRRC59,FTSJ3,KCNAB2,MRPL57,PLK3,ERCC1,RHOBTB3,AATF,GABPA,EHMT1,MRPL43,KIF15,WDHD1,TOPORS,SMC2,DIDO1,MCM2,RAB22A,GINS4,KRIT1,STOML2,BRMS1,AHNAK,MID1IP1,SMAD2,RAD18,WDR11,RPS27A,MYO18A,KLHL42,AAAS,ANXA11,DDX42,SSRP1,MRPL9,MRPS2,DHX9,RAB23,TOP2B,HAUS4,EIF2AK4,PARN,HAUS2,CDC73,MYL6B,LMNA,MCTS1,DDRGK1,TMEM179B,DDX56,PDXP,SMC3,INTS7,MCM5,RIMS3,RBM34,GEMIN4,MRPL21,MVP,PABPC1,NUP85,NSUN4,EIF3L,ETV3,ZMYND11,MTA2,TEX10,GTPBP4,RPS10,MYBL2,MAP7D1,MRPL16,SRSF5,MPG,ABCF1,MAGED2,FNTA,CCDC86,PDLIM1,SETD3,SLAIN1,NDE1,ZNF830,CFAP20,PDLIM5,MRPL3,ALS2,ZNF207,RHOG,TRIM41,SARNP,TRERF1,IVNS1ABP,UBR2,POC1A,ACTR3,ANK3,TPX2,MYH9,NUF2,NIT2,INO80E,PRKACA,GLRX3,STMN1,CPNE3,APP,CLUAP1,AHCTF1,SP100,UTP18,MTA1,GRSF1,NUP107,NABP1,NSFL1C,SEPT11,RNF19A,CEP63,ATF2,RPRD1B,RNF169,DCTN1,PSRC1,POLR2L,EID1,KAT7,WBP2,RPL38,POLR2D,CIRBP,CDCA2,NUSAP1,GORAB,DNAJA1,NDUFA7,MEF2D,DDX17,PPP2CA,KIF2A,CDC16,LSM6,CCDC14,NSMCE2,CORO1C,RPLP1,SNRPG,GEN1,LRP8,COIL,TUBB,RPS2,MZT1,SESTD1,ZFP91,HABP4,FLOT1,JMJD6,ABHD14B,ATG2B,IP6K2,ATP5F1B,WDR5,IFT27,RRP36,PNO1,SAPCD2,NEIL2,TUT4,KRI1,CAPN2,RPA2,ADD3,CLIC4,SUV39H2,DCP1A,GTSE1,LTN1,KANSL2,SGCB,RPL22L1,HNRNPM,SPTAN1,NUDC,STAU1,PPP3CA,DDX24,TCTEX1D2,POLK,TACC1,JTB,MRPS10,LLPH,RAB3IP,DDX39A,RPA1,UTP20,KIF18A,KEAP1,POLE,CCDC6,ACOX1,PITX1,MAPK6,LRPPRC,PML,AEN,HMGB2,SSNA1,PARP10,DDX47,THOC1,WDR13,SNX15,CSNK2A1,EBNA1BP2,CDC42SE2,BIRC2,KRR1,TET3,ABL2,DLG5,RAB8A,PCNA,ETV6,XRCC2,POP7,NOC2L,MCMBP,MTPN,MRPL32,TACC3,PLK1,METTL1,RPP25,EXOSC6,SEPT9,PBXIP1,BAZ2A,RAD51AP1,MRPL12,CKAP2L,EZR,CDC6,PBRM1,UTP3,BRCA1,ANLN,EPB41,DPYSL3,SEPT1,TIMM13,FBXO28,TONSL,CHD3,E2F4,ACTB,DVL1,FAM208A,SINHCAF,POT1,MYL12B,C2CD5,CCDC137,ZCCHC9,TMUB1,HJURP,CENPF,CTCF,KLC1,RACGAP1,CDK13,NCKAP1,DNAJB1,PPP3CB,ASXL2,RAPGEF6,ARID1B,SUB1,RB1,VASP,CCP110,RINL,VMP1,MBD2,KIF13B,XPA,CTR9,TIMELESS,MDFIC,RBM3,ICE2,GLE1,MRPL48,NSDHL,ACSL3,LDB1,UTP15,CAMSAP1,RTF1,METTL22,ARPC1A,APPL1,ZNF174,HAUS8,RPL36,PAXX,MBIP,PCM1,CDC27,COX7A2L,NLRC5,PRMT7,DTD1,RUVBL2,MYO9A,BTBD10,ECPAS,CCNB2,BCCIP,USP7,CYLD,RPLP2,MRPL39,DYNLL1,SLC2A1,PCBP1,BCAP31,RPAIN,RAD23A,ABRACL,RPL11,OIP5,MRPL50,PSMA6,MDM2,STRBP,KMT5C,ABRAXAS2,MRPL34,TARDBP,CORO1A,LMAN1,TOP1MT,SAP30L,SPIDR,POC5,PRPF19,KDM3B,RPL29,RPL35,POLR2G,RAB7A,TUBGCP5,NFATC2,DCLRE1C,KDM1B,VDAC1,MRPS14,TMEM201,RPSA,USP36,MRPL2,RBL1,CLK3,CEP55,UHRF2,XRCC3,NCOA1,H3F3A,SMAD4,RAD51D,ZNF146,PARD3,SLC30A9,CTDP1,NIFK,MCM10,C19orf53,MIF4GD,MTERF1,KLHL21,CDT1,AGO2,CDCA8,ARID5A,SMC6,HMGN3,NKRF,CSNK1A1,NCAPG,TUBGCP2,DNAJB9,WRNIP1,STARD9,IRF4,HOMER1,SLC1A4,DDX31,SS18L1,CENPM,PTGES3,POLR1B,ORC3,RBM15B,PPAN,RHOA,HMGN5,PRKDC,TUFM,TOP3A,RANGAP1,ZFR,DDX23,CDKN2AIPNL,ATP6V1D,NEK1,BIRC5,L3MBTL3,FAM110A,SNAP29,CDCA7L,E2F1,USP20,PKD2,RBPJ,CHMP7,IFI16,MAX,H2AFZ,PDCD6IP,TAP1,CCNB1,UBE2I,POLR3K,PARK7,KIFC1,UTP25,ANKRD26,PA2G4,NOL11,PARPBP,TAF5L,CDC25B,MAST2,SMARCE1,DNMT1,SEH1L,CDC5L,NOL12,SGCE,USO1,NOL8,NSUN2,MKI67,DDX20,SUPT20H,AURKB,CCNF,SLC25A5,RFC2,MAK16,CLNS1A,EIF3A,PRIM1,DOT1L,WAS,KIF18B,RPS14,MRPL27,MAP4,EIF2D,PTPN7,RRS1,SLF1,TRAF5,ZMAT3,NMD3,HDAC2,DDX58,HSPH1,RECQL,EWSR1,MAPRE1,POLR2K,CHTF18,KIF23,PMF1,PSEN1,YY1AP1,CNOT3,JMY,SPAG5,RTKN,FKBP1A,TMEM250,CEP104,EXOSC7,KLHL5,ARPC5,MSH2,DAPK1,FBXL7,MRPL40,GNAI2,LPCAT1,TNRC18,EEF1D,TERF2,PHF10,DDX28,PRIM2,SIGMAR1,WDR1,RDH10,SEPT8,RPS24,EXOSC9,PLEC,ARID1A,CAPZA2,FXR1,KDM3A,PATL1,MAP2K2,CCT8,TWISTNB,PHF6,HMGN2,XRCC5,GOLGA2,EPOP,RBMX,APPL2,FAM83D,TCOF1,YY1,CDK2,CDKN2A,NDC1,DNMT3A,ATXN3,TRIP10,SUZ12,URB2,RAC1,MAGED1,OLA1,BCL2L1,SDHA,TERF2IP,PHC2,UCHL5,MRPS27,TTC3,CDK12,CFL1,MRM2,CCT2,CDKN2AIP,BRD4,MAPRE2,RFC3,HMGN4,CUL3,VDAC2,NARF,SLBP,EDF1,PKMYT1,POLG2,H2AFV,GAR1,SHCBP1,TRIM28,EML4,SERP1,CENPU,SUPT16H,NSA2,RAD51C,DSN1,JAK1,MRPL55,PPP2R5A,HINT1,DGCR8,TBL3,FAAP100,H2AFX,STAT1,TRIM32,BEND3,PDCD11,XRCC4,CSNK1D,DYNC1LI2,POLQ,PRPF4B,NCOR2,PKP4,TWNK,MECP2,TCF3,MRI1,BLM,SPDL1,RAB11A,MAD2L2,JAKMIP1,RFWD3,RPL17,CENPJ,PRC1,AXIN2,MRPL54,RPL19,UPF2,CARF,CNN2,CITED2,MAP3K14,CREB1,MTX2,IFT46,MSH6,SMC4,PDLIM2,KAT2A,NEK7,WDR18,ILF3,PARP4,RPL8,BMS1,KIF11,RPL27A,KLF6,MACF1,MARK2,SPPL2B,POLR2A,MYO1F,CBX3,C1orf131,RPL32,TTLL4,KHSRP,CCDC69,DUSP11,ASNA1,DDX5,WDR62,ESPL1,PURA,DEF6,DDB1,IPO4,BYSL,DDX52,POLA2,NPHP4,SKA3,NOP2,NF1,KMT2E,DNAJC24,KIF2C,SIRT2,BRIX1,MAP1LC3B,MAPK14,CUTC,MRPL19,EDC3,UBLCP1,MBD4,DST,ZNF804A,CDC42,SYNM,EIF4A3,JAZF1,DPYSL2,RCSD1,SRI,HADHB,RPF2,KIF22,RP2,TCEA1,CARMIL1,SRPK2,DEAF1,NCK1,FOPNL,RIOX2,TMEM216,WDR82,ARHGDIB,STK17B,ASF1B,DHX15,CHAF1A,ABHD5,RPL37,GEMIN5,UBTF,HSPB11,EIF4ENIF1,BRWD1,SPATA2,NIP7,ATXN2L,PQBP1,BAZ1B,ZNF268,CHEK2,CLU,VPS4A,ROCK1,MRPL13,SASS6,RPS26,CEP170B,RPS15,NSMCE4A,PPP1R12A,ZCCHC8,CIB1,TIA1,RPL15,MEF2A,RGS2,TTF1,LYAR,DTL,BANF1,CAPZA1,BUD31,KIFAP3,YBX1,KNTC1,MCPH1,ATP6V0D1,HP1BP3,POLR2I,OXR1,RPL6,PSMA1,EIF2A,SEPT7,DAPK3,EVC2,MASTL,TSC1,NSMF,CDCA5,ODF2,SLC16A1,NUP62,RBBP4,TSEN15,MZT2B,SMARCD1,WASF2,TCF12,MBD1,CHMP2A,ASH1L,FAM92A,MPHOSPH8,PMS2,SMARCA4,NSD3,ORC1,TWF2,CHD1,MEAF6,MXD1,HNRNPA2B1,SAP130,RRN3,CD3EAP,NVL,KIF14,EXOSC1,AKAP8,CHTOP,UTP4,ABI1,HTRA2,DNAL4,CHP1,ACSL5,PPP1R18,FAM172A,WIPF1,ATXN1,BICD2,MBD3,RPS9,BTBD1,DAP3,HNRNPR,TULP3,STAT6,CHCHD1,ARNTL,ANP32E,GAS2,USP11,AKNA,REEP4,MAPK1,KIF3B,MRPL42,SHPRH,RAE1,SCYL1,DCTN2,CDK2AP2,MRPS26,PAWR,MYO9B,FERMT3,SAC3D1,FBXO5,KIF5B,MZT2A,KLHL20,KMT5A,RRBP1,NABP2,H2AFY,ARHGEF2,TTC17,MRPL11,FBL,STAT3,FRMD8,MICAL3,MYO5A,SAMD4B,GINS1,TELO2,PPP1R9B,ADAM17,HMGN1,NASP,ASPM,PSPC1,HELB,POLR3GL,PRMT2,MEN1,SYMPK,TARS,MAPK3,MFN2,HSPA1B,CNOT9,LEMD2,UPF1,ZNF330,MBD6,CENPT,PREPL,SLF2,TERF1 |
| 1.031e-40 | -92.07 | non-membrane-bounded organelle | cellular component | GO:0043228 | 4138 | 891 | 18223 | 2701 |
FGFR1OP,ADD1,MRPS15,KDM4A,CNTROB,ANKRD23,RBM4,PABPC4,FBXO22,MIS12,RPL23A,CALM2,CDK5,USF1,NEK6,PDS5B,DNM2,NUP153,MOB1A,LRRC59,ZNRD1,SPATC1L,FTSJ3,KCNAB2,MRPL57,PLK3,ERCC1,RHOBTB3,AATF,GABPA,EHMT1,MRPL43,KIF15,WDHD1,TOPORS,SMC2,DIDO1,MCM2,RAB22A,GINS4,KRIT1,STOML2,BRMS1,AHNAK,SMAD2,MID1IP1,WDR11,RAD18,RPS27A,MYO18A,KLHL42,ANXA11,AAAS,SSRP1,DDX42,MRPL9,MRPS2,DHX9,RAB23,TOP2B,HAUS4,EIF2AK4,PARN,CDC73,HAUS2,MYL6B,LMNA,MCTS1,DDRGK1,TMEM179B,DDX56,PDXP,SMC3,INTS7,MCM5,RIMS3,RBM34,GEMIN4,MRPL21,MVP,NUP85,PABPC1,NSUN4,EIF3L,ETV3,ZMYND11,MTA2,TEX10,GTPBP4,RPS10,MYBL2,MAP7D1,MRPL16,SRSF5,MPG,ABCF1,MAGED2,FNTA,CCDC86,PDLIM1,SETD3,SLAIN1,NDE1,ZNF830,CFAP20,PDLIM5,MRPL3,ALS2,ZNF207,RHOG,TRIM41,SARNP,TRERF1,IVNS1ABP,POC1A,UBR2,ACTR3,ANK3,TPX2,MYH9,NIT2,NUF2,INO80E,PRKACA,GLRX3,STMN1,CPNE3,APP,CLUAP1,AHCTF1,SP100,UTP18,GRSF1,MTA1,NSFL1C,NUP107,NABP1,SEPT11,RNF19A,CEP63,ATF2,RPRD1B,RNF169,DCTN1,PSRC1,POLR2L,EID1,KAT7,RPL38,CIRBP,POLR2D,WBP2,CDCA2,NUSAP1,GORAB,MEF2D,DNAJA1,NDUFA7,DDX17,KIF2A,PPP2CA,CDC16,LSM6,CCDC14,CORO1C,NSMCE2,RPLP1,SNRPG,GEN1,LRP8,COIL,TUBB,RPS2,MZT1,SESTD1,ZFP91,HABP4,FLOT1,ATG2B,JMJD6,ABHD14B,ATP5F1B,IP6K2,WDR5,IFT27,RRP36,PNO1,SAPCD2,TUT4,NEIL2,KRI1,CAPN2,RPA2,ADD3,CLIC4,SUV39H2,DCP1A,GTSE1,LTN1,KANSL2,SGCB,RPL22L1,HNRNPM,SPTAN1,NUDC,STAU1,PPP3CA,TCTEX1D2,DDX24,POLK,TACC1,JTB,MRPS10,LLPH,RAB3IP,DDX39A,RPA1,UTP20,KIF18A,KEAP1,POLE,CCDC6,ACOX1,PITX1,MAPK6,PML,LRPPRC,AEN,SSNA1,HMGB2,PARP10,DDX47,THOC1,WDR13,SNX15,CSNK2A1,EBNA1BP2,CDC42SE2,BIRC2,KRR1,TET3,ABL2,DLG5,RAB8A,PCNA,XRCC2,POP7,ETV6,NOC2L,MCMBP,MTPN,MRPL32,TACC3,PLK1,METTL1,RPP25,EXOSC6,SEPT9,PBXIP1,BAZ2A,RAD51AP1,MRPL12,EZR,CKAP2L,CDC6,UTP3,BRCA1,PBRM1,ANLN,DPYSL3,EPB41,SEPT1,TIMM13,FBXO28,TONSL,CHD3,E2F4,ACTB,DVL1,FAM208A,SINHCAF,POT1,MYL12B,C2CD5,CCDC137,TMUB1,ZCCHC9,HJURP,CENPF,CTCF,KLC1,RACGAP1,CDK13,DNAJB1,NCKAP1,PPP3CB,ASXL2,ARID1B,RAPGEF6,RB1,SUB1,VASP,CCP110,VMP1,RINL,KIF13B,MBD2,XPA,TIMELESS,CTR9,RBM3,MDFIC,ICE2,GLE1,MRPL48,NSDHL,ACSL3,LDB1,CAMSAP1,UTP15,RTF1,METTL22,ARPC1A,APPL1,ZNF174,HAUS8,RPL36,PAXX,MBIP,PCM1,CDC27,COX7A2L,NLRC5,PRMT7,DTD1,RUVBL2,BTBD10,MYO9A,ECPAS,CCNB2,BCCIP,USP7,CYLD,RPLP2,MRPL39,DYNLL1,SLC2A1,PCBP1,BCAP31,RPAIN,RAD23A,RPL11,ABRACL,OIP5,MRPL50,PSMA6,MDM2,STRBP,KMT5C,ABRAXAS2,MRPL34,TARDBP,CORO1A,TOP1MT,LMAN1,SAP30L,SPIDR,POC5,PRPF19,KDM3B,RPL29,RPL35,POLR2G,RAB7A,TUBGCP5,NFATC2,DCLRE1C,VDAC1,KDM1B,MRPS14,RPSA,USP36,TMEM201,MRPL2,CLK3,RBL1,CEP55,UHRF2,XRCC3,NCOA1,H3F3A,SMAD4,RAD51D,PARD3,ZNF146,SLC30A9,NIFK,CTDP1,C19orf53,MCM10,MIF4GD,MTERF1,KLHL21,CDT1,AGO2,ARID5A,CDCA8,SMC6,NKRF,HMGN3,NCAPG,CSNK1A1,TUBGCP2,DNAJB9,WRNIP1,IRF4,STARD9,HOMER1,SLC1A4,SS18L1,DDX31,CENPM,PTGES3,POLR1B,ORC3,RBM15B,PPAN,RHOA,HMGN5,PRKDC,TUFM,TOP3A,RANGAP1,ZFR,DDX23,ATP6V1D,CDKN2AIPNL,NEK1,BIRC5,L3MBTL3,FAM110A,SNAP29,CDCA7L,E2F1,USP20,PKD2,RBPJ,CHMP7,IFI16,MAX,PDCD6IP,H2AFZ,TAP1,CCNB1,UBE2I,POLR3K,PARK7,ANKRD26,UTP25,KIFC1,PA2G4,NOL11,PARPBP,TAF5L,MAST2,CDC25B,SMARCE1,DNMT1,SEH1L,CDC5L,NOL12,SGCE,USO1,NOL8,NSUN2,MKI67,DDX20,SUPT20H,AURKB,CCNF,RFC2,SLC25A5,MAK16,CLNS1A,EIF3A,DOT1L,PRIM1,WAS,KIF18B,RPS14,MAP4,EIF2D,MRPL27,PTPN7,RRS1,TRAF5,SLF1,ZMAT3,NMD3,HDAC2,DDX58,HSPH1,RECQL,EWSR1,MAPRE1,POLR2K,CHTF18,KIF23,PMF1,PSEN1,JMY,SPAG5,YY1AP1,CNOT3,RTKN,TMEM250,FKBP1A,CEP104,EXOSC7,KLHL5,ARPC5,MSH2,DAPK1,FBXL7,MRPL40,GNAI2,LPCAT1,TNRC18,EEF1D,TERF2,PHF10,DDX28,PRIM2,SIGMAR1,WDR1,RDH10,RPS24,SEPT8,EXOSC9,CAPZA2,ARID1A,PLEC,FXR1,KDM3A,MAP2K2,CCT8,PATL1,TWISTNB,PHF6,XRCC5,HMGN2,GOLGA2,EPOP,RBMX,FAM83D,APPL2,TCOF1,YY1,CDK2,CDKN2A,NDC1,DNMT3A,ATXN3,TRIP10,URB2,SUZ12,MAGED1,RAC1,OLA1,BCL2L1,SDHA,PHC2,TERF2IP,UCHL5,MRPS27,TTC3,CDK12,CFL1,MRM2,CCT2,CDKN2AIP,BRD4,RFC3,MAPRE2,HMGN4,NARF,VDAC2,CUL3,SLBP,EDF1,PKMYT1,GAR1,SHCBP1,POLG2,H2AFV,SERP1,EML4,TRIM28,CENPU,SUPT16H,NSA2,RAD51C,HINT1,PPP2R5A,MRPL55,JAK1,DSN1,DGCR8,FAAP100,TBL3,STAT1,H2AFX,BEND3,TRIM32,PDCD11,XRCC4,CSNK1D,DYNC1LI2,PRPF4B,POLQ,NCOR2,PKP4,TWNK,MECP2,TCF3,MRI1,BLM,SPDL1,RAB11A,MAD2L2,JAKMIP1,RFWD3,RPL17,CENPJ,AXIN2,PRC1,MRPL54,RPL19,UPF2,CARF,CNN2,CREB1,MAP3K14,CITED2,MTX2,IFT46,MSH6,SMC4,PDLIM2,KAT2A,NEK7,WDR18,RPL8,PARP4,ILF3,BMS1,RPL27A,KIF11,KLF6,MACF1,MARK2,SPPL2B,POLR2A,MYO1F,CBX3,C1orf131,RPL32,TTLL4,KHSRP,CCDC69,DDX5,ASNA1,DUSP11,WDR62,ESPL1,PURA,DDB1,IPO4,BYSL,DEF6,DDX52,POLA2,SKA3,NPHP4,NOP2,KMT2E,NF1,DNAJC24,SIRT2,KIF2C,BRIX1,MAPK14,MAP1LC3B,MRPL19,CUTC,EDC3,UBLCP1,MBD4,ZNF804A,DST,CDC42,SYNM,EIF4A3,DPYSL2,JAZF1,RCSD1,HADHB,SRI,RPF2,KIF22,RP2,TCEA1,CARMIL1,SRPK2,DEAF1,NCK1,FOPNL,TMEM216,RIOX2,WDR82,ARHGDIB,STK17B,DHX15,ASF1B,ABHD5,CHAF1A,RPL37,UBTF,GEMIN5,HSPB11,EIF4ENIF1,BRWD1,NIP7,SPATA2,PQBP1,ATXN2L,BAZ1B,ZNF268,ROCK1,VPS4A,CLU,CHEK2,SASS6,MRPL13,RPS26,CEP170B,RPS15,NSMCE4A,PPP1R12A,ZCCHC8,CIB1,TIA1,RPL15,MEF2A,RGS2,TTF1,LYAR,DTL,BANF1,BUD31,CAPZA1,YBX1,KIFAP3,KNTC1,MCPH1,ATP6V0D1,HP1BP3,POLR2I,OXR1,RPL6,PSMA1,EIF2A,SEPT7,DAPK3,EVC2,MASTL,TSC1,NSMF,CDCA5,ODF2,SLC16A1,NUP62,RBBP4,MZT2B,TSEN15,SMARCD1,MBD1,TCF12,WASF2,CHMP2A,ASH1L,MPHOSPH8,FAM92A,PMS2,SMARCA4,NSD3,ORC1,TWF2,CHD1,MEAF6,MXD1,SAP130,HNRNPA2B1,RRN3,NVL,CD3EAP,KIF14,AKAP8,EXOSC1,CHTOP,UTP4,ABI1,HTRA2,DNAL4,CHP1,ACSL5,PPP1R18,FAM172A,ATXN1,WIPF1,BICD2,MBD3,RPS9,BTBD1,DAP3,HNRNPR,CHCHD1,STAT6,TULP3,ARNTL,ANP32E,GAS2,USP11,AKNA,MAPK1,REEP4,KIF3B,MRPL42,RAE1,SHPRH,CDK2AP2,DCTN2,SCYL1,MRPS26,PAWR,MYO9B,SAC3D1,FBXO5,FERMT3,KIF5B,MZT2A,KLHL20,KMT5A,RRBP1,NABP2,H2AFY,ARHGEF2,TTC17,MRPL11,FBL,STAT3,FRMD8,MYO5A,MICAL3,SAMD4B,GINS1,PPP1R9B,TELO2,ADAM17,HMGN1,NASP,PSPC1,HELB,ASPM,POLR3GL,MEN1,PRMT2,SYMPK,TARS,MFN2,HSPA1B,MAPK3,LEMD2,CNOT9,UPF1,ZNF330,MBD6,CENPT,PREPL,TERF1,SLF2 |
| 3.643e-40 | -90.81 | cell | cellular component | GO:0005623 | 16522 | 2614 | 18223 | 2701 |
HECA,ZBTB10,ABCC10,HEXB,TGOLN2,CCNL2,SYNRG,FBXO22,EEF2K,RAD23B,ATP13A3,DNM2,ZNRD1,FTSJ3,USP34,ERCC1,NRAS,EHMT1,KIF15,HNRNPF,WDHD1,MIER2,DIDO1,MCM2,RAB22A,SMAD2,MID1IP1,RPS27A,MYO18A,OGT,MPV17,COX5A,KLHL42,SMAD1,ZNF75A,ANXA11,SLC25A33,ZNF720,SEC61G,GGA1,MUM1,CCZ1,TRIO,RAB23,KCTD17,HAUS4,EIF2AK4,APH1B,PARN,CDC73,MYL6B,ATG4A,TMEM179B,PDXP,SMC3,TNPO3,GEMIN4,MVP,NUP85,PPP6R1,PABPC1,NSUN4,PPA1,IFRD1,AGGF1,FOXK1,RBM42,GTPBP4,MAP7D1,MRPL16,ELK1,EIF4H,RDH11,MAGED2,KPNA1,ETS2,TYW5,WIPI2,RUFY3,PDLIM5,ACSF2,FAM72D,EXOC3,RHOG,STARD7,VTI1A,C5orf30,SLC35B2,INO80E,RCOR3,LCLAT1,CPNE3,KIAA1147,RBM23,ZNF420,AHCTF1,TBC1D22A,TBC1D14,GMEB1,NSFL1C,SEPT11,ZNF226,GPD1L,ZC3H3,ARL5A,PDCL3,SNX8,ERMP1,EID1,IDH3A,NBPF11,POLR2D,HTATIP2,MEF2D,TMEM147,GSTCD,TANC1,MAT2A,VPS26B,CORO1C,NSMCE2,CAMKMT,PPP5C,PITRM1,TUBB,COMMD10,ZNF445,SRSF6,HABP4,CCM2,FLOT1,BTN3A1,ATG2B,ABHD14B,ATP5F1B,HDGFL2,NEXMIF,TUT4,PPP1R3B,GOLM1,ZBTB45,HUWE1,ZNF260,NAA50,ANXA5,LTN1,KANSL2,UBE3B,NAP1L4,ZNF710,ST8SIA2,RPL22L1,MED22,SPTAN1,STAU1,TCTEX1D2,DDX24,TACC1,USP42,MRS2,LDHA,HEBP2,LLPH,RAB3IP,PICALM,SH3BP5,SLC19A1,ACOX1,PARG,FAM3C,AEN,PARP10,YWHAH,WDR45B,THAP5,FAM129A,TRIM11,YTHDC2,SNX15,RBM8A,ENSA,NENF,SND1,RUFY1,TRIM65,ZER1,PRNP,KRR1,RAB8A,NUP210,NOC2L,EIF5,TACC3,RYBP,PTPN18,MIOS,SNRPB,CDC6,UTP3,PBRM1,ODC1,USP21,TRAM2,FBXO28,GRIPAP1,ARRDC1,ADAM9,DVL1,NUMB,ZNF564,FUBP1,CTU2,PARP12,ZCCHC9,CENPF,LAMTOR3,CHCHD2,NCKAP1,RSAD1,TNS3,SUB1,RINL,SSBP3,KIF13B,MBD2,XPA,AHCY,RBM3,GLE1,MRPL48,LRSAM1,NSDHL,AMD1,CAMSAP1,ZNF761,METTL22,ICAM2,STYXL1,APPL1,BBS12,RXRB,SDHB,PCM1,GALNT2,TMEM168,NLRC5,RUVBL2,MYO9A,BTBD10,ECPAS,CCNB2,USP7,GLT8D1,RPLP2,SUCLG1,ARID2,TMX4,SLC2A1,ATP6V1B2,PCBP1,LYN,BCAP31,VAV1,MRPL50,PSMA6,ZNF473,ZNF302,KMT5C,BRPF3,TARDBP,BCAP29,CTDSP2,SPIDR,PRPF19,PPIF,KDM3B,MND1,CLCN3,BIRC3,RAB7A,PPIE,CHMP2B,VDAC1,EIF3H,TMEM201,GLOD4,IDE,DHX16,UHRF2,CHMP4B,XRCC3,PARD3,BCL2L12,NIFK,C19orf53,MCM10,MTERF1,KLHL21,PDAP1,CDCA8,TMX3,GTF3A,ARF1,SLC12A9,CDK11B,PAGR1,TUBGCP2,DNAJB9,HOMER1,POLR1B,RNF5,RBM15B,PPAN,RHOA,RPRD1A,BTAF1,TOP3A,ARHGEF12,PCGF1,DDX23,RAB18,CACNB1,TRIM26,PDCD6,ATP6V1D,NEK1,L3MBTL3,FAM110A,NEIL3,CTBS,BBX,IMPDH1,TAF12,NR2F2,PGAM1,ARHGAP23,HIPK3,IFI16,TXN,NUP188,H2AFZ,PNISR,TMEM203,PRKCSH,USP39,UBE2I,PARK7,SLC25A37,GLMP,RAB4A,TRA2B,SUCLG2,CISD2,TAF5L,SMARCE1,ZNF800,CDC5L,ZNF524,SGCE,OSBP2,NSUN2,USP22,CLNS1A,EIF3A,ZMYM3,DOT1L,IWS1,MKNK1,WAS,KIF18B,TPP2,C1orf109,ZMAT3,FAM72C,B4GALT2,PRPF38B,RECQL,C9orf78,EWSR1,GADD45G,RRM1,DNAAF5,ACAP1,B4GALT1,CYCS,FAM136A,SUPT7L,ZNF518A,TMEM165,CNOT3,NPLOC4,SPAG5,WDR48,RTKN,TMEM250,CEP104,EXOSC7,KLHL5,LRRC8D,PPP4R1,MSH2,PIGG,OSTF1,FBXL7,MRPL40,TNRC18,SYTL3,APOL1,EIF5A,GCC2,PRIM2,COQ8A,ELL2,RDH10,MFNG,USF3,RPS24,GORASP2,CAPZA2,ADRB2,CCT8,MTR,PHF6,PFDN5,SLCO4A1,GOLGA2,EPOP,RBMX,MED15,PIAS2,APPL2,SAMD8,CDKN2A,NUDT3,ZNF511,NDC1,ATXN3,RAF1,C2orf49,CD320,EPM2A,CCNA2,MTMR4,BRI3,TAP2,TP53BP2,AQR,ILKAP,CDK12,SAP30,BRD4,DRAP1,NARF,LRRC8A,ELP4,ABHD11,PKMYT1,ASB13,SERP1,TRIM28,SUPT16H,EIF3K,CHMP4A,CERS6,ATF6,XRCC4,PRPF4B,ADAM23,NDUFS1,DEPDC1,MECP2,SECISBP2,SPDL1,HMG20A,WWP2,JAKMIP1,SLC25A36,CCNK,DNAJC8,ELP5,AXIN2,CARF,CITED2,ANKRD37,KAT2A,TMEM126B,RABIF,ADSL,PACS1,BMS1,KCNQ1,OTUD3,ARSK,MACF1,KIF11,COMMD4,KLF6,SMAP2,FADD,SH3GLB1,MYO1F,CBX3,SELENOW,TMEM127,INF2,PPP1R11,DUSP11,DDX5,WDR62,TAF6,ESPL1,PURA,DDB1,DEF6,IPO4,FAM83G,UBL3,CCNC,PIGM,LYRM4,GPR132,UBE2Q1,PTP4A3,BRIX1,MRPL19,ZNF696,SF3B2,PCYOX1L,CDC42,SYNM,GOT2,JAZF1,HADHB,RPF2,SLC35C2,CNNM3,CARM1,SRPK2,WDR41,LARS,LRBA,TMEM216,RIOX2,SUMF2,KMT2C,OGFR,MPC1,ASF1B,RPL37,MAN2A2,EIF4ENIF1,NIP7,U2SURP,MIA2,ZNF268,VPS4A,ATP6V0E1,PPP1R2,PM20D2,XPNPEP3,RGS2,LYAR,FAM89B,EI24,POLR2I,SUGP2,GBA,EIF2A,SYVN1,DAPK3,ARHGAP15,MASTL,UAP1,NFIL3,FN3KRP,YWHAZ,CTSA,TMEM14A,TOB1,TSEN15,ADNP2,TCF12,PRKAB1,MDH2,SMARCA4,ORC1,RRN3,UBXN2A,IARS,CD3EAP,KIF14,EXOSC1,CS,CLTB,DNAL4,CSTF1,CHP1,POU2AF1,UBQLN4,NXT1,PPP1R18,PGGT1B,SELPLG,SMU1,LSM8,ATXN1,GLO1,OGDH,BICD2,CADM1,EDEM2,TOLLIP,FANCE,MBD3,PDHX,RPS9,ALKBH6,SURF4,DUS3L,ARNTL,ANP32E,FKBP5,CCDC125,ABCA1,PDCD2L,CWC25,GCLM,ZNF316,RAE1,DCTN2,NUP54,CHIC2,PAWR,MXD4,DCUN1D4,PIP4K2A,XPR1,FERMT3,KIF5B,KLHL20,SEC24C,RRBP1,DUS2,ARHGEF2,ANP32A,LDLRAD3,STAT3,MYO5A,AMPD2,TXNL1,COA3,PHF20L1,DCAF6,FAM49B,ATP2C1,RFFL,COG1,RCOR1,PRMT2,TFEB,LEMD2,CTSL,UPF1,ELMO1,ZC3H7B,DTX4,ZMIZ1,TERF1,HRAS,SLF2,CCDC93,FGFR1OP,TMED7,MAP3K7CL,PIGQ,AGPAT1,CNTROB,PPP1R16B,EDRF1,MIEN1,MIS12,CIPC,GSDMB,PDS5B,NUP153,SENP1,PGAP2,TMEM115,AATF,DCUN1D5,PLEKHF2,BRMS1,PWWP2B,TRIM47,WDR11,AXIN1,SMG9,TRIM52,LONP2,NDUFV2,PHF23,CERK,SLC4A2,EZH1,ITGB5,LMNA,MCTS1,DDX56,EIF2S2,SLC38A5,FOXN2,CARS2,PRRC2A,RB1CC1,ZMYND11,PGS1,MYBL2,SRSF5,MPG,MATR3,CYB5A,NCDN,POLR2J,SETD3,TEX30,PTAR1,CNOT6,NDE1,PLPP6,EGLN1,ZNF207,ANKRD27,ABCA3,SARNP,IVNS1ABP,RMI2,MON1B,TMEM97,NIT2,RXYLT1,NUF2,ZNF267,TCF19,KTN1,APP,PRKD3,CLUAP1,ATP2A2,UTP18,GRSF1,DUT,ZCCHC2,ANAPC7,RNF19A,FAM76B,CLN6,TMEM9,GCC1,RNF169,ADCY7,ATP6V1G1,ENPP4,RNPS1,CDCA2,FKBP3,DDX17,CHCHD3,PEX5,CDC16,HIPK2,NT5C3B,MBOAT1,TICAM1,PDXK,ZBTB11,ANXA6,TMBIM4,GMCL1,UBE4A,IL21R,ETS1,WRB,PLPP5,ZNF92,PNO1,CAPN2,ADD3,SUV39H2,TPCN1,TMX1,HNRNPM,LYPLA2,MFSD12,LDHB,PPP3CA,POLK,JTB,EMP3,MTMR12,ZP3,PDE3B,CIP2A,KIF18A,CCDC6,WNT5B,MAPK6,C4orf46,LY75,SLC25A19,RGL1,PSAP,WDR76,IGBP1,FAF1,SNAPIN,COX15,THOC1,AGRN,GNPDA1,GPBP1L1,PPP1R15B,CSNK2A1,EBNA1BP2,GIT2,BIRC2,ATPAF1,DLG5,ABL2,XRCC2,ZFYVE27,MCMBP,PTPRK,CDC37,SP3,METTL1,EXOSC6,HARS,CYSTM1,GMFB,ESYT1,ANLN,RAB5B,RHEB,DPYSL3,TBC1D17,TIMM13,CDCA4,TONSL,NRM,NAGLU,ACTB,ZNF45,SINHCAF,C2CD5,TMUB1,CTCF,ASAH1,DOCK11,CRLF3,ASXL2,LRRC14,NUS1,CMTR2,SLC27A4,AFF1,MDFIC,MAML1,CYTH1,NQO2,UTP15,EIF2AK1,EIF4G2,ZDHHC3,SPATA33,MOSPD3,CDC27,SNAP23,TBPL1,PRMT7,ATP5F1A,KCTD7,NDUFA5,CYLD,UGP2,DYNLL1,COPE,HCFC1R1,ZADH2,GGPS1,RPAIN,RAD23A,ABRACL,SEC11A,ATP6V0B,PDK2,ZBTB21,TNFAIP8,STRBP,DUS4L,MRPL34,PDCD2,SAP30L,CLPTM1,RPL29,TIMP2,RPL35,BTG2,TUBGCP5,DNAJC9,FRAT2,MTMR6,NFATC2,KDM1B,ARL5B,USP36,MRPL2,ATP1A1,CLK3,MAFK,PSMD3,NDUFA11,CEP55,PLGRKT,ZNF436,DNAJC17,NCOA1,SLC25A39,ZC3HC1,ZNF146,CDC40,SMAP1,GOLIM4,GNE,SMC6,ARFIP2,NKRF,CHAC2,BZW2,WRNIP1,SS18L1,CENPM,PTGES3,CAMK2G,MLEC,ZNF202,PPWD1,FAM50B,RHOT2,NEU1,GOLGA7,GLG1,PGRMC1,FAM126A,SPCS3,RPS6KC1,UBE2C,PPCS,NDUFB6,ZDHHC8,PLXNA1,CCNB1,SLC20A1,COMMD6,RIC1,ABHD14A,POLR3K,C14orf119,UTP25,ASAP2,SNUPN,CNPY4,SPTSSA,PLCL2,TFG,SEH1L,ATG9A,ARHGAP45,PBK,MKI67,DDX20,AMDHD2,GALNT7,SLC17A5,CCNF,FOXRED1,RBM47,WDR4,DHTKD1,SARAF,TRAF5,HDAC2,PWWP2A,HSPH1,LIME1,MAPRE1,CHTF18,ADO,KIF23,SLC35B1,NOTCH2,PMF1,COPG2,JMY,NDUFAF6,FKBP1A,SLC31A1,SNX18,ATIC,CTPS1,SLC25A51,ATP6V0A2,PIKFYVE,RNF135,LPCAT1,EEF1D,TMED2,FTL,PHF10,DDX28,ZNF84,SIGMAR1,PIP4K2C,RIT1,PLEC,CYFIP2,KDM3A,SF3A2,FAS,EPRS,ZNF777,QARS,CSNK1G1,DCAF11,PPP3R1,TCOF1,NRBP1,CABLES1,DNMT3A,RWDD1,TRIP10,SF3B1,RPS6KA1,SUZ12,CAST,RAC1,GPR89A,OLA1,SNN,SDE2,GNB2,FLAD1,APLP2,KDM2A,TNPO2,CDKN1B,TALDO1,GPX4,ATP13A1,MAPRE2,RFC3,ERF,TAOK1,CUL3,SLBP,H2AFV,POLG2,GAR1,PSMB9,CENPU,DHX57,SOCS7,NSA2,HSPA4,MRPL55,JAK1,FAAP100,TBL3,GOLGA8A,SEL1L,H2AFX,B4GALT3,PDCD11,ATMIN,CSNK1D,POLQ,POU3F2,OTUD5,NCOR2,ANKRD13D,PKP4,SCAMP3,TWNK,BABAM1,CDCA3,SLC25A12,BLM,TMCC3,GTF2F1,RPL17,CRAT,AHSA1,PRC1,UPF2,COPS7B,SLC38A10,CNOT6L,CNPY3,UBE2M,IFT46,TSHZ1,ZFP64,STRIP1,DENND4C,DENND1B,WDR18,RPL8,ILF3,LRRC1,RHOT1,MARK2,TSR2,ECH1,PRDX1,POLR2A,PLD3,NUCB1,FBXO21,GNA12,C1orf131,PRDX3,PFDN4,CCZ1B,HNRNPH3,STX18,TFDP1,NAXE,KHSRP,ASNA1,CPEB2,BYSL,VPS29,DDX52,S100PBP,MIB2,ADA2,IER2,PTMS,NOP2,UBN1,NF1,DCAF15,ALKBH5,MOGS,UBE2Z,TAF6L,BECN1,MAPK14,SNAPC4,RNF103,BCAT2,MBD4,CYREN,CMSS1,METTL14,IMPAD1,RCSD1,PHTF1,SRI,KHDC4,KIF22,ZBTB22,NFU1,OGG1,TRIM14,ELOF1,COPS8,FYTTD1,TRIM8,RRM2,SOX4,ABHD5,UBTF,CXXC4,PAF1,SPATA2,PQBP1,IARS2,ATXN2L,GALNT10,ROCK1,STARD3NL,CEP170B,RPS15,PIGN,AGTRAP,CIB1,CDIP1,XPO7,SRRT,APOPT1,ZNF449,CAPZA1,GLTP,KIFAP3,BCL2,N4BP2,HP1BP3,VOPP1,ISG15,CAND1,GNAS,TSC1,RBM25,CDCA5,ZFP90,NANP,RBBP4,NIPSNAP2,HNRNPDL,ZBTB24,SMARCD1,MBD1,WASF2,MMACHC,TOMM20,IFI27L1,GNPNAT1,FAM92A,MPHOSPH8,HNRNPUL2,NSD3,CHD1,MEAF6,MIEF1,BABAM2,CCDC50,AKAP8,PARL,RPN2,CHTOP,F2R,TMEM14C,SCYL3,ABI1,HTRA2,MOSPD1,RLIM,FAM172A,ZNF500,PSMB7,NLN,WIPF1,BOLA1,ERBIN,BUD13,NDUFB1,PEF1,EIF3G,BTBD1,TAB2,CHCHD1,TULP3,WDR59,CANT1,SCARB1,GAS2,USP11,SMURF1,TSPAN5,PPP2R2D,CDS2,MAGEH1,MRPL42,EYA1,CDK2AP2,MRPS26,LETMD1,KLF13,HDDC2,RGS1,MAN1A1,FBXO5,GART,PELO,TANK,BRD7,MRPL11,SAMD4B,ZDHHC18,GTF3C6,POLR3GL,WDR81,MEN1,ZNF407,MFN2,COX8A,ZRANB2,SRSF3,MBD6,ATP6V1C1,IDH3B,TATDN1,TSC2,LACTB2,CMTM6,RBM4,ZNF275,RPL23A,CDKN2C,NAPG,USF1,DNAAF2,MECR,AP1M1,UPRT,CRY2,ECD,RNF26,MOB1A,TIPARP,LRRC59,ANKRD9,MGAT5,RHBDD2,MRPL57,BAK1,ZNF559,RHOBTB3,GABPA,NUTF2,COA7,GINS4,ARF4,KRIT1,BOLA3,AHNAK,RAD18,PDRG1,RNASEL,CHPF2,OAZ1,SMNDC1,PDCD4,NXT2,HIVEP3,CLSPN,RHOC,DHX9,PDCD7,PSMD9,HAUS2,COPB2,TFAP4,CD59,RNFT1,RBM34,RIMS3,MEGF8,FBXO7,EFTUD2,MYDGF,MRPL21,CPSF4,PHKG2,LUC7L2,SRSF11,EIF3L,MAPKAPK3,MTA2,SF3B6,ERO1A,MTFR2,USP10,ITM2A,SSR2,BCLAF1,MTX1,SFXN5,FNTA,PDLIM1,TXNDC16,CFAP20,ZNF830,MRPL3,NUP58,ALS2,FAM72A,TRIM41,KARS,GGNBP2,NQO1,POC1A,PTTG1,ANK3,TPX2,TBC1D13,DAZAP2,STMN1,GLRX3,REPS1,SH3BP1,MTA1,UBA5,CLCN6,NABP1,MICU2,INTS12,RPRD1B,CGGBP1,CPNE1,ULK3,SEC61B,POLR2L,FAM118B,KAT7,GOPC,CRNKL1,E2F3,CIRBP,RPL38,PFKFB3,GORAB,RAB1A,PPP2CA,KIF2A,ALDH3B1,CCDC14,LSM6,RNF38,DMWD,SNRPG,CENPBD1,USP13,MZT1,ZFP91,TRMT6,IP6K2,WDR5,SLC25A43,IFT27,PMVK,RRP36,NEIL2,SAPCD2,SRXN1,RPA2,PSMD2,CLIC4,PDCD10,ITGB8,COQ4,ARF5,ARHGEF1,GTF2H2,FBXL19,UTP20,MAGT1,GPS2,DBI,SSNA1,CD81,AAMDC,WDR13,FANCI,PAPOLA,CREM,TET3,FANCL,TIMM23,GLIS2,IL6ST,INTS1,POP7,SLC44A1,MTPN,ASB6,PLK1,RPP25,SEPT9,CELSR2,RBX1,APH1A,RAD51AP1,ZBED5,CKAP2L,PSMG1,UBE2V1,IL12RB1,EAF2,KRTCAP2,LUC7L,LSG1,NECAP2,TRIM4,ALG3,AGPAT2,CHD3,ZNF367,E2F4,PRPF4,KPNA2,BEND6,CLN3,DNAJC30,FAM208A,NGLY1,POT1,MYL12B,CCDC137,RMND5A,NEMP2,HJURP,PHB2,DNAJB2,NKD2,SDC2,KLC1,CDK13,COX4I1,RAB6A,DNAJB1,CNOT11,ARID1B,C1GALT1,MLX,UBE2Q2,CCP110,ZNF746,ARL6IP1,CTR9,ICE2,NIPSNAP1,ABHD2,DCAF8,ACSL3,LDB1,MAP4K3,ARMC8,NPIPA1,RBM38,IRF5,RMC1,NMT2,RPL36,HAUS8,PAXX,MBIP,ORMDL2,COX7A2L,LAMTOR4,ZDHHC7,SIL1,DTD1,UNC13C,BCCIP,SART1,TRAF7,NDUFAF2,TOR1AIP1,ZNF416,LAGE3,ZFYVE21,RRAGC,ZNF121,OIP5,NRF1,ABRAXAS2,WDR44,PIN1,PPME1,RPAP1,TOP1MT,LMAN1,AHCYL1,STRAP,SPSB3,ZNF583,SNX25,ARHGAP17,POLR2G,ZNF780B,PPT1,NUP155,DCLRE1C,MRPS14,RHBDF2,AFDN,SUGP1,RBL1,FASTK,UBXN2B,STK38,AP1S1,SPRYD4,SLC22A23,H3F3A,CHID1,SMAD4,RAD51D,SLC30A9,NADSYN1,UNK,CMAS,AGO2,HMGN3,NCAPG,SCYL2,FZD6,HERC3,GTPBP3,CTSS,ORC3,YTHDC1,ACP2,CSRP1,HMGN5,PRKDC,ABCF2,TUFM,RANGAP1,PNPLA8,HAGH,API5,ZFR,SEC23IP,E2F1,USP20,TMEM219,RBPJ,MAX,PDCD6IP,LUZP1,ADAM10,CXXC1,TSC22D3,AP3M2,CUL1,GYG1,NANS,OAT,MYEF2,ANKRD26,PA2G4,MTFR1L,NOL11,FIZ1,ZNF200,AP2B1,FBXW2,MARCH2,SLC26A2,SRSF10,SRP72,KLF10,LACTB,SUPT20H,CBFB,RFC2,RAB2B,PRIM1,MAP3K4,HHEX,BRD2,RPS14,LUC7L3,MAP4,MRPL27,BTF3,PTPDC1,SLF1,CCDC59,NMD3,PTOV1,COX5B,DNAJC5,SCOC,DHPS,POLR2K,ANKH,PRKAA1,VAV2,GSPT2,DLGAP4,TATDN3,PXMP2,PRPF39,PSEN1,ZNF79,PDXDC1,VPS25,NDUFS7,YY1AP1,C12orf10,FAM192A,RPN1,LHX8,ARPC5,ZNRF2,DAPK1,TPST1,PIK3IP1,CYC1,MRM3,SOCS5,FDFT1,GID8,PIGT,CPQ,WDR1,EMB,ZNF574,C1orf35,EXOSC9,ARID1A,PTTG1IP,FXR1,GOSR1,MAP2K2,TWISTNB,AKAP1,XRCC5,HMGN2,PI4K2A,SEC31A,CAT,DERL1,HSPBP1,MTHFD2,CEBPG,ARAP1,FAM83D,USP32,CABIN1,SMPD4,GPI,CYTIP,TP53RK,REPS2,RAB11B,UROD,SLC39A13,POMP,BCL2L1,NUDT19,DECR1,RALB,SIAH1,LPIN2,ADCY9,SOCS6,MRPS27,TTC3,RNASEH2A,CFL1,ANKLE2,CDC123,VDAC2,EDF1,ERC1,EML4,ANKZF1,ZNF282,RAD51C,DSN1,DDOST,HINT1,RAB24,DGCR8,SAFB,FTSJ1,NCLN,BEND3,EYA2,DYNC1LI2,SLC41A1,B4GALT5,MANBA,TKT,FAM76A,CBLL1,ARGLU1,LANCL1,POFUT1,HEATR5B,HLA-A,EBP,RFWD3,NDUFA2,FUT8,PTPN11,MRPL54,FEM1B,RPL19,CNN2,NDUFA3,MTX2,MSH6,PDLIM2,LONRF3,RFXANK,FBXO9,GUF1,SPPL2B,RPL32,ZHX1,OAZ2,NDUFS5,WDR91,GPR89B,HIGD2A,ZBED3,RORB,POLA2,ZNF76,MTX3,COPA,KMT2E,UQCR10,HMGXB3,ABCB10,COMMD5,MAP1LC3B,ATP5PF,DST,SIVA1,RAB35,GPATCH1,TCEA1,CARMIL1,DRAM2,DEAF1,TRAPPC13,SNRNP200,NCK1,LAP3,VHL,SREK1,ARHGDIB,PITPNB,HSPB11,BRWD1,PPM1G,SH3GLB2,CRCP,BAZ1B,CAB39,STK11,CLU,CHEK2,MRPL13,CHPT1,DCAF5,CAPN1,UBE2D3,NSMCE4A,PPP1R12A,ZCCHC8,GORASP1,NACA,UBXN1,PCSK7,EPN1,RPL15,THRAP3,TTF1,QSOX2,NUP205,PRPF18,CHKA,DTL,MED10,PYURF,ORAI1,TENM3,ZRANB1,MCPH1,SLC12A2,ATP6V0D1,CSNK1G3,ATP5IF1,CREG1,NUDT4,ERLIN1,RPL6,VKORC1,SLTM,EVC2,KLHL15,SIAH2,SLC16A1,DNPH1,EHD4,SNRNP70,C11orf1,APOL2,N4BP2L2,SNX27,CHMP2A,CORO7,FEZ2,PMS2,UCK2,UCK1,CLCC1,EXT2,MXD1,USP5,HNRNPA2B1,SAP130,NVL,PPP6C,CYB5R1,UTP4,ZNF770,EBAG9,RNF25,PCGF6,FAM72B,PON2,VPS26C,HNRNPR,HPS5,STAT6,MAPK1,TMEM33,PDF,NAT14,DNAJC2,TRIP12,SHPRH,SCYL1,VPS45,MYO9B,GFM2,SPPL2A,FASTKD3,FGFR3,MZT2A,GRK2,PPIG,KMT5A,ZDHHC13,NABP2,H2AFY,ATG13,NDUFS8,FBL,SLC35A1,FRMD8,MICAL3,TGFB1,B3GALT6,ELOVL5,PPP1R9B,HEMK1,TIMMDC1,HELB,PSPC1,MIER1,NADK2,NDRG3,CDK11A,MTMR3,ACAT1,KMT2B,CENPT,PLOD3,RAB3IL1,ZSWIM6,RAB14,ADD1,MRPS15,KDM4A,XIAP,DHX8,GLUD1,ANKRD23,PABPC4,CALM2,CDK5,PSMD1,NEK6,NSRP1,RABGAP1L,SRSF4,FNIP2,SPATC1L,KCNAB2,PCBP2,MLST8,PLK3,ZNF672,MRPL43,HSDL1,TOPORS,MCL1,SMC2,PPFIA3,ICMT,SLC50A1,STOML2,LIMK1,ZNF689,PRDX5,VIPAS39,ATE1,MLYCD,ATP6V0C,ST3GAL2,FBXL3,TFDP2,E2F2,PFKP,AAAS,DDX42,SSRP1,MRPL9,MRPS2,STRN4,TOP2B,ZNRF3,TMED3,DDRGK1,RAVER2,GNS,INTS7,INPP5A,MCM5,PHF14,ZNF326,RTCB,UBE2QL1,NAGPA,TIMM8B,CYFIP1,ETV3,TSPYL4,TSPAN31,DHX29,TEX10,MAN1B1,RPS10,CBFA2T2,ABCF1,RHOB,PTPRF,SCARB2,OSBPL11,CCDC86,DUSP3,CSK,SLAIN1,MDH1,HEXA,SGF29,RNF139,SNX14,ZNF296,FAM208B,TRERF1,UBR2,CHD1L,ACTR3,WDTC1,MYH9,CREBL2,NIPA2,PRKACA,SAFB2,ANKIB1,STAM,RAB21,SP100,ZKSCAN1,DDA1,NUP107,ANKRD13C,MAVS,CEP63,RBM15,ATF2,DCTN1,SHOC2,PSRC1,INTS13,MAP4K4,WBP2,ATP6V0A1,NUSAP1,DNAJA1,NDUFA7,TAZ,TAF2,SEC61A1,WDR7,RPLP1,RBMS1,FUS,GEN1,LRP8,COIL,LRCH1,GALK1,ZNF786,RPS2,SESTD1,TRAK1,JMJD6,SIKE1,AKT1S1,KRI1,FBXO3,ERH,GATC,NDUFB4,PPP1R8,PRDM4,GTSE1,GEMIN6,DCP1A,SGCB,S100A6,IMPA2,NUDC,PDPK1,MOB4,TK1,GUK1,TNFAIP3,GALC,ZNF512,MRPS10,DDX39A,RPA1,ZNF180,ZNF862,KEAP1,POLE,TATDN2,PITX1,CAPN7,LRPPRC,PML,HMGB2,USF2,ANAPC4,SRM,DDX47,MCCC1,CDC42SE2,S1PR2,CDIPT,SEC16A,KCMF1,SSR1,LIN9,PCNA,ZNF639,TRMU,PIK3R2,ETV6,PPCDC,TXLNA,MYBL1,MRPL32,CCAR1,ABCC5,PBXIP1,BAZ2A,TLK1,MRPL12,EZR,LRP5,BRCA1,PRKRA,STX16,EPB41,OPTN,SEPT1,SOCS4,QRSL1,PIEZO1,DHFR2,OSGEPL1,GLCCI1,NUDT11,NAA60,GEMIN7,SEPHS2,LZTR1,RACGAP1,PPP3CB,B4GALT4,RLF,RAPGEF6,SNRNP25,RB1,VASP,MED8,TIGAR,VMP1,PPIL2,MEA1,TIMELESS,ALDH18A1,TMEM8A,ABCC1,PREB,TRAPPC9,AACS,MEMO1,KRAS,RTF1,UBE4B,NFATC2IP,LY6E,ARPC1A,ZNF174,PSMC4,GOLGA4,PALB2,SYNCRIP,NIPA1,TIGD2,RNF114,FOXM1,MRPL39,XAB2,SUMO2,DUSP22,COMMD8,RPL11,CSDE1,MDM2,CORO1A,MINPP1,POC5,DVL2,GM2A,PSMA8,COQ10B,CPOX,TIGD5,SLC26A6,PRPF3,TXNL4A,RPSA,SRSF1,DNAJC10,SCAP,ZNF700,TIMM17A,TOMM6,LTA4H,AP2S1,INTS2,CTDP1,MIF4GD,CDT1,ARID5A,SUMF1,GGA2,AP3S1,CSNK1A1,RMI1,TFRC,PTPN2,STARD9,IRF4,GSTK1,NDUFV1,SLC1A4,CWC27,SLC35B4,DDX31,ABCD1,RPAP3,CNTN5,SNX2,ZMYM5,BORA,CHCHD6,KPNA4,CDKN2AIPNL,FBXO41,BIRC5,TFE3,SNAP29,CDCA7L,PKD2,ACADM,CHMP7,SAT2,GCSH,ZNF496,TMEM109,TAP1,YTHDF3,NHLRC3,IKBIP,KIFC1,DBNDD1,CYB5RL,PARPBP,CDC25B,MAST2,DNMT1,NOL12,ORAI2,USO1,AKT2,NOL8,GNG7,ELOA,MRNIP,AURKB,MCFD2,SLC25A5,ZFAND5,MAK16,STT3A,TMED10,PSMD8,EIF2D,ITGB1,PTPN7,UQCRH,RRS1,ARRB2,RTN3,SVIP,DDX58,WSB2,PPIB,MUT,GMFG,HLA-E,NDUFA4,MAN2B1,METTL3,CFLAR,NDUFS4,RNF121,MEX3C,KLF16,HDAC7,DAD1,BDH1,PCYT2,GNAI2,ANKHD1,TERF2,MORC3,NOA1,KCTD20,SEPT8,DCTD,PKM,TOMM40,PATL1,PSMB3,ADSS,SERTAD2,SERF2,ZFP92,NSF,DCK,ERGIC3,ACLY,LPCAT4,VCPIP1,YY1,PPP6R2,MAP3K5,PPP6R3,RNF14,CDK2,ZC3HAV1,SYS1,ZBTB37,URB2,EIF3D,MAGED1,KLHL18,ADPGK,SLC25A44,AP1B1,SDHA,PAIP2,PHC2,CRKL,MOAP1,TERF2IP,CYHR1,ZNF75D,SHC1,UCHL5,NAA35,TMBIM1,MRM2,CCT2,CDKN2AIP,MKLN1,HMGN4,LYRM1,GALK2,CDC23,SHCBP1,AP4E1,PRDM11,VEZF1,PPP2R5A,GUCY1B1,STAT1,PPA2,TRIM32,RHEBL1,R3HCC1L,TCF3,MRI1,BRAP,AGPAT3,MYNN,SDF2L1,SPR,RAB11A,REEP5,FOXO3,MAD2L2,PIP5K1C,RBM17,MAT2B,PTEN,CENPJ,TAGLN2,OSTC,MAP3K14,CREB1,PACS2,NCOA2,SMC4,RNASEH2C,NEK7,NET1,PARP4,TBRG4,ANAPC2,RPL27A,YIF1A,SGSH,HGS,ATP5MC3,TTLL4,SLC38A7,MFAP1,CCDC69,BRWD3,ESYT2,SKA3,NPHP4,HNRNPAB,PLXNC1,ST13,DNAJC24,ZNF107,KIF2C,SLC29A1,AGFG1,SIRT2,FKBP2,USP48,UBQLN2,SNRPD3,CUTC,EDC3,UBLCP1,ZNF804A,RAP1A,THADA,EIF4A3,AP3S2,ATG3,DPYSL2,PPP1R12C,AKR1B1,NDUFB9,JOSD1,RP2,TTC4,TECR,ARID4A,FGFR1OP2,TIMM50,TDP1,DPM1,FOPNL,SLC16A7,WDR82,SLC25A22,STK17B,DHX15,CHAF1A,GEMIN5,TIMM29,COPS6,SASS6,RPS26,PSMC1,SLC12A7,TBC1D12,TM9SF4,ZNF768,UFC1,MED13L,TIA1,MEF2A,EPHX2,PITHD1,RHBDD1,NFATC3,BANF1,BUD31,ZNF335,YBX1,KNTC1,ACAD8,UBE3C,ZNF189,ALDH9A1,KDELR1,TSTA3,CIC,OXR1,PSMA1,SEPT7,NAP1L1,NSMF,ODF2,EXOC4,TRMT10B,NUP62,PITPNA,NAA20,PTDSS1,MZT2B,PDSS2,TMEM106C,IMMT,ASH1L,CHERP,WDYHV1,PLAGL2,CHKB,IRF3,TWF2,PAIP1,ANKRD28,ANKLE1,FARSA,SAR1A,APOOL,PDIA6,ACSL5,CGAS,DMAC2,TOR1AIP2,AZI2,GFER,RAD54B,DAP3,ZNF317,GADD45B,AKNA,REEP4,CBX4,MIF,KIF3B,GOLPH3L,SH2D3A,CASP6,TOR3A,SRGN,DBF4,TIMM21,MFSD10,SAC3D1,CTNNBL1,YIF1B,CLDND1,TTC17,SLC25A1,GINS1,PAQR6,CSNK1G2,TELO2,ADAM17,HMGN1,NASP,ASPM,PRKAR1B,ATP5MF,SYMPK,TARS,SNRPA,MAPK3,HSPA1B,CNOT9,HLA-B,ATAD2,PLAA,ZNF330,OSBPL8,KBTBD7,PREPL |
| 4.847e-40 | -90.53 | CUL3 (cullin 3) | protein interactions | 8452 | 1193 | 370 | 17029 | 2761 |
ZBTB10,PDCD6IP,MRPS15,DHX8,CUL1,GLUD1,RBM4,PABPC4,ANKRD39,RPL23A,CALM2,PSMD1,SRSF4,AP2B1,SUCLG2,TRA2B,NUP153,TFG,SMARCE1,FTSJ3,PCBP2,CDC5L,SRP72,RHOBTB3,NSUN2,ELOA,HNRNPF,AURKB,DCUN1D5,SLC25A5,RFC2,ARF4,BRMS1,RPS14,EIF2D,VIPAS39,KLHL42,RRS1,ARRB2,PFKP,SMNDC1,HSPH1,EWSR1,DHX9,KCTD17,NDUFA4,PRPF39,TMEM165,COPB2,WDR48,RPN1,SMC3,KLHL5,EFTUD2,ZNF326,RTCB,DAPK1,CTPS1,MRPL21,PABPC1,LUC7L2,SRSF11,DDX28,PRRC2A,WDR1,MTA2,MTFR2,RPS10,KCTD20,C1orf35,RPS24,EXOSC9,BCLAF1,GORASP2,ARID1A,PLEC,SRSF5,PKM,FXR1,SF3A2,MATR3,CCT8,PHF6,XRCC5,ADSS,SEC31A,MAGED2,EPRS,MTHFD2,KPNA1,NSF,QARS,RBMX,ACLY,USP32,ZC3HAV1,FAM208B,SF3B1,MAGED1,WDTC1,KLHL18,AP1B1,SAFB2,PRKACA,SDHA,APP,ATP2A2,GRSF1,DUT,NUP107,MRPS27,NSFL1C,ATF2,DCTN1,CCT2,CDKN2AIP,RPL38,CIRBP,CUL3,RNPS1,DNAJA1,H2AFV,ERC1,TRIM28,MAT2A,SUPT16H,DDX17,PPP2CA,HSPA4,DGCR8,SAFB,RPLP1,FTSJ1,TRIM32,FUS,SNRPG,DMWD,PDXK,PDCD11,NKAPD1,DYNC1LI2,TUBB,GALK1,RPS2,NDUFS1,TRMT6,TKT,MYNN,GMCL1,SDF2L1,LANCL1,ATP5F1B,WDR5,RBM17,FBXO3,RPA2,PSMD2,CBWD2,RPL17,HUWE1,AHSA1,RPL19,COPS7B,NAP1L4,UBE2M,MSH6,HNRNPM,SPTAN1,LDHB,STAU1,DDX24,WDR18,RPL8,ILF3,LDHA,MACF1,PRDX1,FADD,KEAP1,PRDX3,HNRNPH3,KHSRP,DDX5,WDR76,WDR91,YWHAH,PURA,DDB1,GPATCH4,IPO4,FAF1,UBE2E2,HNRNPAB,NOP2,YTHDC2,EBNA1BP2,SND1,SNRPD3,BRIX1,SEC16A,MAP1LC3B,MRPL19,FANCI,SSR1,KRR1,SF3B2,DLG5,PCNA,EIF4A3,THADA,PIK3R2,TXLNA,TECR,MCMBP,CARM1,TIMM50,SRPK2,COPS8,LARS,EXOSC6,SNRNP200,RBX1,SNRPB,MRPL12,SLC25A22,USP21,DHX15,GEMIN5,TIMM13,BRWD1,U2SURP,ATXN2L,ACTB,KPNA2,PRPF4,COPS6,PSMC1,FUBP1,RPS15,LZTR1,ZCCHC8,NACA,UBXN1,TIA1,RPL15,XPNPEP3,DNAJB1,SRRT,NUP205,LYAR,KIF13B,CAPZA1,YBX1,RBM3,AHCY,ALDH18A1,HP1BP3,NTPCR,MEMO1,UTP15,RPL6,ARMC8,PSMC4,CAND1,RPL36,SDHB,NAP1L1,PALB2,SYNCRIP,KLHL15,FN3KRP,SLC16A1,NUP62,YWHAZ,RUVBL2,ATP5F1A,SNRNP70,BTBD10,NIPSNAP2,HNRNPDL,KCTD7,USP7,NDUFA5,SART1,RPLP2,MRPL39,XAB2,SUMO2,HNRNPUL2,SMARCA4,CLCC1,COMMD8,PAIP1,RPL11,CSDE1,HNRNPA2B1,MRPL50,OIP5,FARSA,STRBP,IARS,NVL,AKAP8,TARDBP,RPN2,PDIA6,DVL2,PRPF19,RPL35,CPOX,SMU1,DNAJC9,NUP155,ERBIN,PEF1,RPS9,EIF3G,BTBD1,SRSF1,DNAJC10,PON2,MRPL2,ATP1A1,HNRNPR,FAU,GCLM,NIFK,RRP15,KLHL21,RAE1,DCTN2,AGO2,MRPS26,NKRF,DCUN1D4,NCAPG,GART,KLHL20,PPIG,SEC24C,RRBP1,PELO,H2AFY,SS18L1,FBL,MRPL11,CAMK2G,RPAP3,RHOA,ASPM,PSPC1,PRKDC,PRKAR1B,TUFM,ARHGEF12,WDR81,TARS,SNRPA,ZFR,HSPA1B,MTMR3,KPNA4,UPF1,KBTBD7,PGRMC1,ACAT1,ZRANB2,ACADM,SRSF3,PLOD3 |
| 5.978e-40 | -90.32 | MOV10 (Mov10 RISC complex RNA helicase) | protein interactions | 4343 | 1009 | 328 | 17029 | 2761 |
PNISR,KDM4A,AGPAT1,DHX8,MIEN1,PA2G4,PSMD1,CIPC,MECR,SMARCE1,RHBDD2,MLST8,ZNF672,OSBP2,NOL8,NUTF2,ARMH3,USP22,FOXRED1,PLEKHF2,PRIM1,ZMYM3,IWS1,MKNK1,KIF18B,LUC7L3,C1orf109,MYO18A,MPV17,SARAF,RRS1,E2F2,SMNDC1,HDAC2,DDX42,PPIB,COX5B,POLR2K,GSPT2,C16orf87,STRN4,DLGAP4,DHX9,DNAAF5,KIF23,SLC4A2,HAUS4,MAN2B1,TMED3,METTL3,LMNA,NPLOC4,FAM192A,SLC31A1,PDXP,HDAC7,PHF14,CYC1,MYDGF,ANKHD1,LUC7L2,GID8,AGGF1,PRIM2,SIGMAR1,WDR1,RPS10,RPS24,BCLAF1,ARID1A,SRSF5,C9orf40,EIF4H,MTR,CAT,SEC31A,EPOP,QARS,VCPIP1,NDE1,ZC3HAV1,NUDT3,CDKN2A,ZNF207,NQO1,RAF1,UROD,SAFB2,PRKACA,CRKL,FLAD1,AHCTF1,SHC1,SP100,MRPS27,CLCN6,TNPO2,RNASEH2A,ZC3H3,TMBIM1,SZRD1,DCTN1,SNX8,GOPC,CIRBP,CUL3,EDF1,MEF2D,TANC1,ASB13,TAZ,SUPT16H,PEX5,CDC16,HSPA4,SEC61A1,DSN1,DDOST,DGCR8,VPS26B,NT5C3B,KLHDC4,PDXK,PPP5C,ZBTB11,LRP8,USP13,OTUD5,RPS2,PKP4,R3HCC1L,BABAM1,JMJD6,POFUT1,HMG20A,MAD2L2,PIP5K1C,EBP,WWP2,RFWD3,RPA2,PSMD2,CENPJ,TAGLN2,NAP1L4,MTX2,HNRNPM,NUDC,JMJD4,STAU1,TK1,GUK1,DDX24,STRIP1,WDR18,RFXANK,ILF3,TBRG4,MRPS10,HEBP2,POLR2A,RPA1,SELENOW,SH3BP5,INF2,HGS,MAGT1,ATP5MC3,TATDN2,HNRNPH3,OAZ2,LRPPRC,SLC25A19,HMGB2,ESPL1,IPO4,FAM83G,SRM,ZNF76,HNRNPAB,AGRN,NOP2,COPA,GNPDA1,UQCR10,UBE2Z,KIF2C,GIT2,FANCI,PCYOX1L,MBD4,LIN9,PIK3R2,TXLNA,NOC2L,KHDC4,KIF22,MCMBP,ABCC5,CDC37,FYTTD1,TDP1,PTPN18,HARS,APH1A,LRBA,BRCA1,PITPNB,RAB5B,LSG1,DHX15,ASF1B,GEMIN5,CHD3,E2F4,CRCP,GALNT10,MRPL13,RPS26,SEPHS2,PIGN,HJURP,LAMTOR3,EPN1,B4GALT4,XPO7,RAPGEF6,NUP205,SNRNP25,TNS3,NFATC3,VASP,MED8,CCP110,ZNF746,FAM89B,RBM3,ALDH18A1,ZRANB1,NIPSNAP1,TRAPPC9,NSDHL,NQO2,SUGP2,RPL6,NFATC2IP,ZNF174,PSMC4,CAND1,TSC1,PALB2,RBM25,ZDHHC7,YWHAZ,ATP5F1A,MYO9A,NIPSNAP2,ADNP2,TCF12,MBD1,TOMM20,MPHOSPH8,ATP6V1B2,BCAP31,USP5,ATP6V0B,SAR1A,NVL,CS,EFCAB11,TARDBP,CHTOP,AHCYL1,STRAP,UTP4,SPSB3,CHP1,PRPF19,SLC39A9,KDM3B,DMAC2,DNAJC9,OGDH,VDAC1,SRSF1,SURF4,SCAP,CLK3,PSMD3,CANT1,AP1S1,SPRYD4,USP11,SLC25A39,RAD51D,KIF3B,CDC40,GOLPH3L,MRPS26,ARFIP2,LETMD1,NKRF,FBXO5,HERC3,GRK2,SEC24C,ARHGEF2,MRPL11,FBL,STAT3,PPAN,COA3,DCAF6,RPRD1A,ABCF2,WDR81,ZFR,CTSL,TPD52L2,UPF1,PDCD6,TWSG1,ZC3H7B,E2F1,ATP6V1C1,IDH3B,CHMP7,HRAS |
| 6.274e-39 | -87.96 | NXF1 (nuclear RNA export factor 1) | protein interactions | 10482 | 1125 | 352 | 17029 | 2761 |
PNISR,NUP188,KDM4A,AGPAT1,DHX8,CUL1,NANS,UBE2I,SLC20A1,MIEN1,PARK7,PSMD1,CIPC,RABGAP1L,TRA2B,CRY2,NUP153,PLCL2,SMARCE1,SEH1L,MLST8,AATF,OSBP2,PBK,NOL8,MCL1,NUTF2,ARMH3,USP22,FOXRED1,PRIM1,KRIT1,IWS1,ZMYM3,ANKRD10,AHNAK,KIF18B,LUC7L3,TPP2,C1orf109,MYO18A,OGT,SARAF,HDAC2,DDX42,NXT2,COX5B,STRN4,DLGAP4,DHX9,DNAAF5,KIF23,SLC4A2,HAUS4,MAN2B1,TMED3,HAUS2,LMNA,NPLOC4,FAM192A,SLC31A1,PDXP,MEX3C,RNFT1,HDAC7,MEGF8,TNPO3,MYDGF,ANKHD1,AGGF1,SIGMAR1,WDR1,SSR2,BCLAF1,ARID1A,C9orf40,MTR,SEC31A,EPRS,PDLIM1,EPOP,QARS,RBMX,VCPIP1,NDE1,SNX14,CDKN2A,NUDT3,ZNF207,TRERF1,NQO1,SUZ12,RAF1,ACTR3,UROD,PRKACA,SDHA,PAIP2,ABHD16A,CRKL,FLAD1,DECR1,CLUAP1,AHCTF1,SHC1,SP100,GRSF1,NUP107,MRPS27,TNPO2,AQR,TP53BP2,RBM15,ZC3H3,TMBIM1,SZRD1,DCTN1,SNX8,CCT2,ULK3,GOPC,CIRBP,CUL3,RNPS1,MEF2D,CDC23,TANC1,ASB13,SHCBP1,TAZ,SUPT16H,HSPA4,CDC16,PEX5,SEC61A1,DSN1,DDOST,VPS26B,NT5C3B,CAMKMT,KLHDC4,PDXK,PPP5C,ZBTB11,LRP8,PKP4,BABAM1,JMJD6,POFUT1,MAD2L2,EBP,WWP2,RFWD3,PSMD2,CENPJ,TAGLN2,NAP1L4,HNRNPM,NUDC,JMJD4,GUK1,TNFAIP3,DDX24,STRIP1,RFXANK,ILF3,MRPS10,ADSL,BMS1,RHOT1,POLR2A,CIP2A,SH3BP5,FBXO21,INF2,HGS,MAGT1,TTLL4,ATP5MC3,TATDN2,HNRNPH3,OAZ2,LRPPRC,SLC25A19,HMGB2,DDX5,ESPL1,DDB1,IPO4,FAM83G,SRM,ZNF76,HNRNPAB,COPA,AGRN,GPBP1L1,GNPDA1,NF1,RBM8A,CSNK2A1,UBE2Z,EBNA1BP2,KIF2C,FANCI,KRR1,PCYOX1L,MBD4,LIN9,EIF4A3,PIK3R2,TXLNA,NOC2L,RPF2,KHDC4,NDUFB9,KIF22,MCMBP,ABCC5,SRPK2,CDC37,FYTTD1,PTPN18,HARS,APH1A,RIOX2,LNX2,PITPNB,RAB5B,LSG1,DHX15,ASF1B,GEMIN5,CHD3,E2F4,CRCP,KPNA2,GALNT10,ROCK1,SEPHS2,PIGN,HJURP,UBXN1,EPN1,B4GALT4,XPO7,RAPGEF6,NUP205,SNRNP25,TNS3,NFATC3,VASP,MLX,MED8,CAPZA1,SLC27A4,CTR9,GLE1,ALDH18A1,ZRANB1,HP1BP3,NIPSNAP1,TRAPPC9,NSDHL,NQO2,KRAS,NFATC2IP,ZNF761,EIF2A,PSMC4,CAND1,TSC1,RBM25,ZDHHC7,NUP62,YWHAZ,RUVBL2,ATP5F1A,MYO9A,NIPSNAP2,TOB1,ADNP2,TCF12,MBD1,TOMM20,MPHOSPH8,BCAP31,USP5,HNRNPA2B1,ATP6V0B,SAR1A,AKAP8,CS,EFCAB11,TARDBP,CHTOP,AHCYL1,STRAP,CHP1,PRPF19,SLC39A9,UBQLN4,ARHGAP17,NXT1,ANKRD33B,DMAC2,OGDH,VDAC1,PDHX,SRSF1,SURF4,SCAP,PSMD3,CANT1,USP11,SLC25A39,RAD51D,ATXN7L2,KIF3B,CDC40,SH2D3A,RAE1,DCTN2,LETMD1,NKRF,FBXO5,HERC3,SEC24C,SLC35B4,H2AFY,ARHGEF2,FBL,LDLRAD3,STAT3,RBM15B,GTF3C6,DCAF6,RPRD1A,ABCF2,RANGAP1,WDR81,ZFR,MFN2,CTSL,TPD52L2,PDCD6,ATAD2,ZC3H7B,E2F1,SRSF3,IDH3B,CHMP7,IFI16 |
| 3.161e-38 | -86.35 | RNA binding | molecular function | GO:0003723 | 1848 | 486 | 17224 | 2647 |
TXN,PNISR,ADD1,MRPS15,YTHDF3,DHX8,LACTB2,UBE2I,EIF1B,RBM4,MYEF2,PARK7,PABPC4,EEF2K,RPL23A,UTP25,PA2G4,SNUPN,NOL11,NSRP1,SRSF4,TRA2B,CISD2,SMARCE1,LRRC59,DNMT1,FTSJ3,PCBP2,SRSF10,CDC5L,SRP72,NOL12,USO1,AATF,NOL8,NSUN2,MRPL43,MKI67,HNRNPF,WDHD1,DIDO1,SLC25A5,MAK16,CLNS1A,EIF3A,RCC1L,AHNAK,SMAD2,RBM47,RPS27A,RPS14,LUC7L3,MRPL27,MAP4,EIF2D,MYO18A,BTF3,RNASEL,RRS1,SMAD1,ZNF598,CCDC59,NMD3,ZMAT3,HDAC2,ANXA11,SMNDC1,PDCD4,DDX42,SSRP1,DDX58,PPIB,PRPF38B,MRPL9,EWSR1,MAPRE1,GSPT2,DHX9,EIF2AK4,PRPF39,PARN,METTL3,MCTS1,RAVER2,RPN1,DDX56,EXOSC7,EIF2S2,MEX3C,RBM34,EFTUD2,ZNF326,RTCB,MRPL40,MRPL21,CPSF4,ANKHD1,MRM3,PABPC1,NSUN4,LUC7L2,EEF1D,MORC3,SRSF11,EIF5A,CYFIP1,EIF3L,DDX28,AGGF1,RBM42,PRRC2A,DHX29,NOA1,SF3B6,GTPBP4,RPS10,USP10,RPS24,C1orf35,BCLAF1,FAM133B,EXOSC9,MRPL16,PLEC,SRSF5,PKM,FXR1,CYFIP2,EIF4H,PATL1,ABCF1,SF3A2,MATR3,PHF6,AKAP1,HMGN2,XRCC5,EPRS,CCDC86,RBMX,TYW5,CNOT6,TCOF1,YY1,CFAP20,MRPL3,CDKN2A,ZC3HAV1,ZNF207,KARS,SARNP,NQO1,SUZ12,CAST,SF3B1,EIF3D,MYH9,EFL1,SAFB2,GLRX3,CPNE3,KTN1,PAIP2,CRKL,RBM23,UTP18,GRSF1,UCHL5,DUT,MRPS27,NABP1,RNASEH2A,AQR,RBM12B,RBM15,ZC3H3,CDKN2AIP,SEC61B,CRNKL1,RPL38,POLR2D,RNPS1,CIRBP,SLBP,NUSAP1,EDF1,GAR1,FKBP3,TRIM28,DHX57,SUPT16H,DDX17,EIF3K,NSA2,DGCR8,LSM6,SAFB,TBL3,RBMS1,TRIM32,FUS,SNRPG,PPP5C,PDCD11,PRPF4B,RPS2,SRSF6,MECP2,TRMT6,HABP4,JMJD6,SECISBP2,RRP36,PNO1,TUT4,HLA-A,GTF2F1,JAKMIP1,KRI1,RBM17,ERH,RPL17,HUWE1,PPP1R8,ARHGEF1,DCP1A,MRPL54,RPL19,UPF2,NAP1L4,GTF2H2,RPL22L1,HNRNPM,STAU1,DDX24,TRIR,RPL8,ILF3,TBRG4,LLPH,BMS1,DDX39A,MACF1,RPL27A,MARK2,POLR2A,PRDX1,UTP20,C1orf131,RPL32,MFAP1,HNRNPH3,LRPPRC,KHSRP,DUSP11,DDX5,HMGB2,WDR62,CPEB2,PURA,GPATCH4,BYSL,DDX52,DDX47,THOC1,NOP2,HNRNPAB,FLYWCH2,YTHDC2,RBM8A,ALKBH5,EBNA1BP2,SND1,AGFG1,SNRPD3,BRIX1,EDC3,PAPOLA,SF3B2,KRR1,CMSS1,GOT2,EIF4A3,METTL14,TRMU,POP7,NOC2L,HADHB,RPF2,GPATCH1,KHDC4,EIF5,MRPL32,CCAR1,TIMM50,SRPK2,METTL1,RPP25,FYTTD1,SNRNP200,EXOSC6,BAZ2A,RAD51AP1,SNRPB,MRPL12,SREK1,EZR,UTP3,BRCA1,KMT2C,PRKRA,LUC7L,DHX15,RPL37,GEMIN5,UBTF,EIF4ENIF1,NIP7,CHD3,U2SURP,ATXN2L,IARS2,PRPF4,KPNA2,DHFR2,MRPL13,FAM208A,RPS26,PSMC1,CCDC137,FUBP1,CTU2,RPS15,PARP12,ZCCHC9,ZCCHC8,ZNF768,TIA1,RPL15,CDK13,THRAP3,SRRT,LYAR,SUB1,MBD2,RBM3,YBX1,ALDH18A1,NTPCR,NUDT4,SUGP2,RPL6,UTP15,PSMA1,RTF1,EIF2A,EIF4G2,SLTM,RBM38,RPL36,NAP1L1,SYNCRIP,RBM25,DTD1,YWHAZ,ATP5F1A,SNRNP70,HNRNPDL,BCCIP,NOP9,SART1,IMMT,SUCLG1,CHERP,MRPL39,MDH2,SUMO2,HNRNPUL2,SMARCA4,TWF2,PCBP1,PAIP1,RPL11,HNRNPA2B1,CSDE1,FARSA,PSMA6,MDM2,STRBP,IARS,CD3EAP,NVL,EXOSC1,AKAP8,CS,TARDBP,CORO1A,CHTOP,AHCYL1,UTP4,STRAP,CSTF1,RPL29,RPL35,POLR2G,FAM172A,PPIE,ATXN1,LSM8,PRPF3,BUD13,PEF1,MRPS14,EIF3G,RPS9,EIF3H,USP36,RPSA,SRSF1,SUGP1,MRPL2,DAP3,DUS3L,DHX16,CLK3,HNRNPR,FASTK,CHCHD1,DNAJC17,FAU,LTA4H,CBX4,DNAJC2,NIFK,UNK,CDC40,MIF4GD,MTERF1,MRPL42,PDAP1,EYA1,RAE1,AGO2,ARID5A,MRPS26,GTF3A,NKRF,ARF1,CDK11B,GFM2,TFRC,FASTKD3,PPIG,RRBP1,DUS2,ANP32A,DDX31,MRPL11,ERI3,FBL,MYO5A,RBM15B,YTHDC1,PPAN,SAMD4B,CSRP1,HMGN5,PSPC1,PRKDC,HELB,TUFM,RANGAP1,API5,SNRPA,ZFR,TARS,DDX23,HSPA1B,TPD52L2,SEC23IP,UPF1,ZC3H7B,IMPDH1,ZRANB2,SRSF3,IFI16 |
| 5.435e-38 | -85.81 | cell cycle | biological process | GO:0007049 | 1351 | 382 | 17256 | 2622 |
FGFR1OP,NUP188,MAX,PDCD6IP,TSC2,XIAP,CUL1,USP39,CNTROB,CCNB1,UBE2I,MIS12,KIFC1,CDK5,CDKN2C,PA2G4,NEK6,RABGAP1L,PDS5B,DNM2,NUP153,CDC25B,SEH1L,MLST8,CDC5L,PLK3,ERCC1,PBK,NSUN2,KIF15,MKI67,MRNIP,WDHD1,SMC2,USP22,AURKB,CCNF,MCM2,RFC2,PRIM1,KIF18B,RPS27A,MAP4,ITGB1,KLHL42,RRS1,TFDP2,E2F2,AAAS,ANXA11,MAPRE1,CLSPN,PHF23,CHTF18,RHOC,GSPT2,PRKAA1,RRM1,KIF23,TOP2B,HAUS4,EIF2AK4,PMF1,NOTCH2,HAUS2,CDC73,LMNA,SPAG5,CNOT3,JMY,MCTS1,RTKN,TMEM250,SMC3,SNX18,MCM5,MSH2,FBXL7,GNAI2,NUP85,TERF2,PRIM2,RB1CC1,ZMYND11,MYBL2,SEPT8,RHOB,GOLGA2,FAM83D,APPL2,ARAP1,VCPIP1,CNOT6,NDE1,ZNF830,CDK2,CABLES1,NUP58,CDKN2A,ZNF207,NDC1,DNMT3A,RPS6KA1,UBR2,POC1A,PTTG1,ANK3,ACTR3,TPX2,MYH9,CREBL2,NUF2,BCL2L1,PRKACA,STMN1,SDE2,CCNA2,AHCTF1,SIAH1,RALB,NUP107,NABP1,SEPT11,CDKN1B,ANAPC7,TP53BP2,CEP63,ATF2,CFL1,DCTN1,ANKLE2,PSRC1,MAPRE2,RFC3,BRD4,CDC123,ERF,EID1,INTS13,TAOK1,CUL3,E2F3,SLBP,CDCA2,NUSAP1,PKMYT1,CDC23,EML4,CENPU,TAF2,PPP2CA,KIF2A,RAD51C,CDC16,CHMP4A,DSN1,GOLGA8A,NSMCE2,H2AFX,PPP5C,CSNK1D,TUBB,DYNC1LI2,MZT1,MECP2,BABAM1,CDCA3,BLM,SPDL1,RAB11A,MAD2L2,SAPCD2,RFWD3,RPA2,CCNK,ERH,SUV39H2,CENPJ,PTPN11,PRC1,NAA50,GTSE1,CNOT6L,MSH6,SMC4,NUDC,PPP3CA,TACC1,NEK7,WDR18,JTB,TBRG4,ANAPC2,KIF11,RPA1,KIF18A,POLE,MAPK6,TFDP1,PML,CCDC69,SSNA1,WDR62,ESPL1,THAP5,ANAPC4,SSSCA1,POLA2,GPR132,SKA3,KMT2E,ENSA,CSNK2A1,KIF2C,SIRT2,BECN1,BIRC2,FANCI,PRNP,LIN9,RAB8A,PCNA,NUP210,RAB35,XRCC2,KIF22,MCMBP,MYBL1,CARM1,CCAR1,TACC3,PLK1,SEPT9,TLK1,RRM2,EZR,CDC6,BRCA1,PBRM1,SOX4,ANLN,RHEB,OPTN,CHAF1A,EPB41,SEPT1,CHD3,E2F4,PPM1G,CAB39,STK11,CHEK2,VPS4A,SASS6,PPP1R12A,HJURP,PHB2,CENPF,LAMTOR3,CIB1,RACGAP1,RGS2,CRLF3,CNOT11,NUP205,RB1,CCP110,BANF1,TIMELESS,KNTC1,MCPH1,SEPT7,EIF4G2,APPL1,RBM38,MASTL,HAUS8,TSC1,PCM1,CDC27,LAMTOR4,CDCA5,ODF2,SIAH2,SLC16A1,NUP62,RBBP4,CCNB2,BCCIP,CHMP2A,PRKAB1,CYLD,FOXM1,DYNLL1,RRAGC,ORC1,OIP5,ANKLE1,MDM2,BABAM2,ABRAXAS2,PPME1,KIF14,PIN1,AKAP8,PPP6C,CABLES2,POC5,MND1,BIRC3,BTG2,TUBGCP5,NUP155,AZI2,CHMP2B,TXNL4A,RAD54B,RBL1,CEP55,UHRF2,XRCC3,CHMP4B,GAS2,REEP4,MAPK1,PPP2R2D,PDCD2L,PARD3,ZC3HC1,RAD51D,CTDP1,KIF3B,MCM10,KLHL21,RAE1,CDT1,DCTN2,NUP54,DBF4,CDCA8,CDK11B,CSNK1A1,NCAPG,TUBGCP2,SAC3D1,FBXO5,STARD9,KMT5A,PELO,NABP2,BRD7,ARHGEF2,CENPM,ORC3,CAMK2G,MICAL3,TGFB1,GINS1,PPP1R9B,RHOA,NASP,ASPM,PRKDC,TOP3A,RANGAP1,MEN1,BORA,CDK11A,MAPK3,MFN2,CNOT9,LEMD2,NEK1,UPF1,BIRC5,E2F1,PKD2,CENPT,UBE2C,CHMP7,HRAS,TERF1 |
| 6.388e-38 | -85.64 | CUL7 (cullin 7) | protein interactions | 9820 | 655 | 239 | 17029 | 2761 |
RAB14,DDX47,HNRNPAB,COPA,NOP2,PRKCSH,CSNK2A1,USP39,GLUD1,EBNA1BP2,SND1,SNRPD3,BRIX1,MAPK14,SLC20A1,MYEF2,RBM4,PABPC4,RPL23A,SF3B2,PA2G4,PCNA,NUP210,NOL11,EIF4A3,GOT2,HADHB,NOC2L,RPF2,TECR,TFG,LRRC59,PCBP2,TIMM50,SRSF10,CDC5L,SNRNP200,RBX1,SNRPB,MKI67,HNRNPF,EZR,AURKB,SLC25A5,RAB5B,DHX15,STOML2,UBTF,AHNAK,LUC7L3,RPS14,U2SURP,BAZ1B,COX5A,KPNA2,RRS1,MRPL13,RPS26,AAAS,PFKP,HDAC2,DDX42,SSRP1,FUBP1,PPIB,EWSR1,CENPF,DHX9,RPL15,RACGAP1,TOP2B,THRAP3,SRRT,NUP205,LMNA,DDX56,SMC3,ATIC,EFTUD2,RTCB,ZNF326,CAPZA1,YBX1,AHCY,SLC12A2,PABPC1,EEF1D,NIPSNAP1,HP1BP3,EIF5A,ERLIN1,TEX10,ACSL3,SF3B6,RPS10,RPL6,GTPBP4,BCLAF1,PLEC,CAPZA2,PKM,FXR1,ARPC1A,EIF4H,SF3A2,CCT8,MATR3,XRCC5,RPL36,PTPRF,EPRS,NAP1L1,SYNCRIP,PDLIM1,RBM25,QARS,RBMX,ACLY,YWHAZ,GPI,TCOF1,ATP5F1A,RUVBL2,SNRNP70,RBBP4,HNRNPDL,SART1,IMMT,RPLP2,RAB11B,MDH2,SF3B1,ACTR3,HNRNPUL2,OLA1,SAFB2,PCBP1,APP,CHD1,RPL11,CRKL,HNRNPA2B1,RAB21,IARS,ATP2A2,SAR1A,PIN1,NUP107,CS,TARDBP,PDIA6,RBM15,CFL1,PRPF19,CCT2,RPL29,RPL35,RAB7A,IDH3A,SMU1,RNPS1,NUP155,GLO1,RAB1A,H2AFV,TRIM28,RPS9,RPSA,SRSF1,SUPT16H,DDX17,AFDN,CHCHD3,ATP1A1,DDOST,SURF4,HNRNPR,DHX16,SAFB,CORO1C,TBL3,FUS,MAPK1,PDCD11,MIF,NIFK,RPS2,RRP15,RAE1,SRSF6,FLOT1,ARGLU1,ARF1,ATP5F1B,TFRC,HLA-A,KIF5B,PSMD2,GART,RRBP1,H2AFY,ANXA5,RPL19,TAGLN2,FBL,UBE2M,NUDC,PPAN,STAU1,PSPC1,PRKDC,WDR18,TUFM,LDHA,RPL8,ILF3,RANGAP1,RPL27A,MACF1,SNRPA,TARS,ZFR,POLR2A,PRDX1,RPA1,CBX3,DDX23,PLD3,PRDX3,HNRNPH3,LRPPRC,PGRMC1,ACAT1,KHSRP,DDX5,ASNA1,SRSF3,IDH3B,DDB1 |
| 2.230e-37 | -84.39 | gene expression | biological process | GO:0010467 | 3791 | 834 | 17256 | 2622 |
ZBTB10,KDM4A,MRPS15,DHX8,CCNL2,EDRF1,RBM4,ZNF275,PABPC4,EEF2K,RPL23A,USF1,CIPC,NSRP1,SRSF4,CRY2,NUP153,ECD,ZNRD1,FTSJ3,PCBP2,MRPL57,BAK1,ZNF672,ZNF559,GABPA,MRPL43,HNRNPF,WDHD1,MIER2,TOPORS,DIDO1,STOML2,BRMS1,SMAD2,RPS27A,ZNF689,OGT,VIPAS39,RNASEL,TFDP2,SMAD1,E2F2,ZNF75A,LONP2,AAAS,SMNDC1,SLC25A33,DDX42,SSRP1,HIVEP3,MRPL9,MRPS2,DHX9,EZH1,PDCD7,APH1B,CDC73,MCTS1,RAVER2,TFAP4,DDX56,EIF2S2,INTS7,EFTUD2,ZNF326,RTCB,FOXN2,GEMIN4,MRPL21,CPSF4,PABPC1,NUP85,NSUN4,PPA1,LUC7L2,CARS2,SRSF11,EIF3L,AGGF1,ETV3,FOXK1,RB1CC1,DHX29,ZMYND11,SF3B6,ERO1A,TEX10,TYW1,GTPBP4,RPS10,MYBL2,BCLAF1,MRPL16,SRSF5,CBFA2T2,ELK1,EIF4H,ABCF1,POLR2J,ETS2,SETD3,TYW5,CNOT6,ZNF830,SGF29,MRPL3,NUP58,ZNF296,KARS,SARNP,TRERF1,IVNS1ABP,PTTG1,CREBL2,ZNF267,INO80E,EFL1,SAFB2,PRKACA,GLRX3,RCOR3,TCF19,APP,RBM23,ZNF420,SP100,UTP18,ZKSCAN1,MTA1,GRSF1,GMEB1,NUP107,NABP1,INTS12,ZNF226,ATF2,RBM15,ZC3H3,RPRD1B,CGGBP1,CPNE1,POLR2L,EID1,KAT7,INTS13,CRNKL1,WBP2,RPL38,POLR2D,RNPS1,E2F3,NDUFA7,MEF2D,DDX17,TAF2,PPP2CA,CHCHD3,LSM6,HIPK2,RPLP1,RBMS1,FUS,SNRPG,PPP5C,ZBTB11,COMMD10,ZNF786,RPS2,ZNF445,SRSF6,TRMT6,HABP4,JMJD6,WDR5,ETS1,NEXMIF,RRP36,PNO1,ZNF92,TUT4,KRI1,CAPN2,ZBTB45,GATC,SUV39H2,PPP1R8,PRDM4,ZNF260,NAA50,LTN1,GEMIN6,ZNF710,GTF2H2,RPL22L1,HNRNPM,MED22,PDPK1,ZNF512,MRPS10,DDX39A,UTP20,ZNF180,ZNF862,KEAP1,PITX1,LRPPRC,PML,HMGB2,USF2,THAP5,SNAPIN,DDX47,THOC1,GPBP1L1,YTHDC2,RBM8A,CSNK2A1,EBNA1BP2,SND1,BIRC2,PAPOLA,CREM,KRR1,LIN9,NUP210,GLIS2,ZNF639,INTS1,ETV6,TRMU,POP7,NOC2L,EIF5,MYBL1,MRPL32,CCAR1,RYBP,SP3,METTL1,RPP25,EXOSC6,HARS,BAZ2A,APH1A,SNRPB,MRPL12,PBRM1,EAF2,UTP3,BRCA1,PRKRA,LUC7L,USP21,CHD3,ZNF367,E2F4,QRSL1,PRPF4,DVL1,OSGEPL1,CLN3,ZNF45,BEND6,FAM208A,NAA60,GEMIN7,ZNF564,FUBP1,SEPHS2,CTU2,ZCCHC9,PHB2,CTCF,CHCHD2,CDK13,RLF,ASXL2,CNOT11,ARID1B,SNRNP25,SUB1,RB1,MLX,MED8,MBD2,CMTR2,SSBP3,ZNF746,CTR9,TIMELESS,MDFIC,RBM3,ICE2,GLE1,MRPL48,MAML1,PREB,LDB1,UTP15,RTF1,ZNF761,EIF4G2,RBM38,IRF5,ZNF174,RXRB,RPL36,SYNCRIP,TBPL1,PRMT7,RUVBL2,SART1,CYLD,TRAF7,RPLP2,ARID2,FOXM1,MRPL39,DYNLL1,XAB2,LAGE3,ZNF416,RRAGC,PCBP1,COMMD8,ZNF121,RPL11,SEC11A,MRPL50,ZBTB21,NRF1,ZNF473,KMT5C,DUS4L,ZNF302,MRPL34,RPAP1,TARDBP,AHCYL1,STRAP,SAP30L,ZNF583,DVL2,PRPF19,KDM3B,RPL29,RPL35,POLR2G,ZNF780B,BTG2,PPIE,NUP155,NFATC2,PRPF3,KDM1B,TXNL4A,MRPS14,RHBDF2,EIF3H,RPSA,SRSF1,SUGP1,MRPL2,DHX16,ZNF700,RBL1,MAFK,ZNF436,DNAJC17,NCOA1,SMAD4,INTS2,SLC30A9,CTDP1,NIFK,CDC40,MTERF1,RRP15,AGO2,ARID5A,GTF3A,NKRF,PAGR1,GTPBP3,IRF4,CTSS,CWC27,SS18L1,POLR1B,RBM15B,YTHDC1,RPRD1A,HMGN5,ZNF202,ZMYM5,TUFM,PPWD1,PCGF1,DDX23,BIRC5,L3MBTL3,TFE3,CDCA7L,BBX,E2F1,RBPJ,SPCS3,TAF12,NR2F2,HIPK3,IFI16,GCSH,NUP188,TXN,ZNF496,MAX,ADAM10,CXXC1,USP39,CCNB1,EIF1B,COMMD6,POLR3K,MYEF2,UTP25,PA2G4,SNUPN,NOL11,FIZ1,ZNF200,TRA2B,TAF5L,DNMT1,ZNF800,SEH1L,CDC5L,SRSF10,ZNF524,KLF10,NOL8,NSUN2,ELOA,DDX20,USP22,CBFB,MAK16,CLNS1A,EIF3A,IWS1,HHEX,BRD2,RPS14,LUC7L3,MRPL27,WDR4,EIF2D,BTF3,RRS1,ARRB2,ZNF598,CCDC59,HDAC2,PTOV1,PRPF38B,EWSR1,LIME1,DHPS,POLR2K,PRKAA1,GSPT2,NOTCH2,PMF1,SUPT7L,PRPF39,ZNF79,PSEN1,ZNF518A,METTL3,VPS25,YY1AP1,CNOT3,FKBP1A,LHX8,EXOSC7,KLF16,HDAC7,MRPL40,MRM3,EEF1D,EIF5A,PHF10,ZNF84,ELL2,NOA1,ZNF574,RPS24,EXOSC9,ARID1A,CYFIP2,KDM3A,SF3A2,TWISTNB,PHF6,XRCC5,EPRS,ZNF777,SERTAD2,ZFP92,RBMX,QARS,MED15,CEBPG,PIAS2,YY1,RNF14,NRBP1,ZNF511,NDC1,ATXN3,TP53RK,RWDD1,ZBTB37,SF3B1,SUZ12,EIF3D,C2orf49,TERF2IP,SPINDOC,ZNF75D,KDM2A,UCHL5,LPIN2,MRPS27,AQR,NAA35,CDK12,MRM2,SAP30,BRD4,ERF,DRAP1,SLBP,ELP4,EDF1,POLG2,GAR1,TRIM28,CENPU,DHX57,PRDM11,SUPT16H,NSA2,EIF3K,VEZF1,ZNF282,MRPL55,HINT1,DGCR8,SAFB,TBL3,STAT1,FTSJ1,PPA2,ATF6,BEND3,PDCD11,EYA2,ATMIN,CSNK1D,PRPF4B,POU3F2,NCOR2,DEPDC1,TWNK,MECP2,TCF3,ARGLU1,SECISBP2,MYNN,FOXO3,HMG20A,MAD2L2,WWP2,GTF2F1,RBM17,CCNK,DNAJC8,RPL17,ELP5,MRPL54,RPL19,UPF2,CARF,CITED2,CREB1,CNOT6L,NCOA2,TSHZ1,ZFP64,KAT2A,WDR18,ILF3,RPL8,RFXANK,TBRG4,BMS1,RPL27A,COMMD4,KLF6,GUF1,TSR2,SPPL2B,FADD,POLR2A,CBX3,RPL32,ZHX1,HNRNPH3,TFDP1,KHSRP,DDX5,DUSP11,WDR62,TAF6,CPEB2,PURA,BYSL,DDX52,RORB,CCNC,ZNF76,IER2,NOP2,KMT2E,PHRF1,ALKBH5,ZNF107,TAF6L,SIRT2,AGFG1,SNRPD3,COMMD5,MAPK14,SNAPC4,MRPL19,ZNF696,SF3B2,EIF4A3,THADA,METTL14,JAZF1,PHTF1,RPF2,GPATCH1,KHDC4,ZBTB22,NFU1,TCEA1,ARID4A,CARM1,ELOF1,SRPK2,FYTTD1,DEAF1,LARS,SNRNP200,RIOX2,SREK1,SOX4,KMT2C,ASF1B,DHX15,RPL37,PAF1,GEMIN5,UBTF,BRWD1,U2SURP,PQBP1,IARS2,CRCP,BAZ1B,ZNF268,CHEK2,MRPL13,RPS26,RPS15,ZCCHC8,ZNF768,NACA,PCSK7,MED13L,RPL15,MEF2A,XPNPEP3,THRAP3,TTF1,SRRT,PRPF18,NUP205,LYAR,NFATC3,ZNF449,MED10,BUD31,ZNF335,YBX1,ACAD8,ZNF189,VOPP1,POLR2I,CIC,SUGP2,RPL6,EIF2A,SLTM,DAPK3,RBM25,NFIL3,NUP62,TRMT10B,ZFP90,RBBP4,NAA20,SNRNP70,HNRNPDL,TSEN15,ZBTB24,ADNP2,TCF12,MBD1,ASH1L,MPHOSPH8,CHERP,SMARCA4,PLAGL2,NSD3,IRF3,CHD1,MEAF6,MXD1,PAIP1,HNRNPA2B1,SAP130,FARSA,RRN3,IARS,CD3EAP,EXOSC1,AKAP8,CHTOP,UTP4,ZNF770,HTRA2,RLIM,CSTF1,POU2AF1,NXT1,ZNF500,METTL2A,SMU1,PCGF6,ATXN1,LSM8,BUD13,MBD3,EIF3G,RPS9,ZNF317,DAP3,DUS3L,HNRNPR,STAT6,CHCHD1,ARNTL,AKNA,MAPK1,BRD9,TSPAN5,CBX4,PDF,CWC25,NAT14,DNAJC2,MRPL42,ZNF316,RAE1,EYA1,SCYL1,SRGN,NUP54,MRPS26,KLF13,PAWR,MXD4,GFM2,SPPL2A,CTNNBL1,KMT5A,PPIG,PELO,RRBP1,DUS2,NABP2,ANP32A,BRD7,MRPL11,FBL,STAT3,SAMD4B,GTF3C6,PPP1R9B,PSPC1,HELB,MIER1,POLR3GL,RCOR1,MEN1,ZNF407,SYMPK,SNRPA,TARS,MAPK3,TFEB,CNOT9,UPF1,ATAD2,ZC3H7B,KMT2B,ZRANB2,SRSF3,ZMIZ1,TYW1B |
| 4.809e-37 | -83.63 | GO_CELL_CYCLE_PROCESS | MSigDB lists | GO_CELL_CYCLE_PROCESS | 1011 | 307 | 17377 | 2626 |
FGFR1OP,PDCD6IP,NUP188,TSC2,XIAP,CUL1,CNTROB,CCNB1,UBE2I,MIS12,KIFC1,CALM2,CDKN2C,PA2G4,PSMD1,NEK6,PDS5B,DNM2,NUP153,CDC25B,SEH1L,MLST8,CDC5L,PLK3,PBK,NSUN2,MKI67,KIF15,AURKB,SMC2,CCNF,MCM2,PRIM1,KIF18B,RPS27A,PSMD8,MAP4,ITGB1,RRS1,TFDP2,AAAS,MAPRE1,CLSPN,RHOC,PRKAA1,KIF23,TOP2B,HAUS4,PMF1,NOTCH2,EIF2AK4,PSMD9,HAUS2,JMY,LMNA,CNOT3,SPAG5,SMC3,INTS7,SNX18,MCM5,MSH2,FBXL7,NUP85,PRIM2,MYBL2,PSMB3,RHOB,GOLGA2,FAM83D,ARAP1,VCPIP1,CNOT6,ZNF830,NDE1,CDK2,CDKN2A,ZNF207,UBR2,ACTR3,ANK3,PTTG1,TPX2,MYH9,NUF2,BCL2L1,PRKACA,STMN1,AHCTF1,CCNA2,RALB,NUP107,CDKN1B,ANAPC7,CEP63,ATF2,DCTN1,ANKLE2,PSRC1,BRD4,MAPRE2,CDC123,TAOK1,CUL3,SLBP,NUSAP1,CDCA2,PKMYT1,CDC23,RAB1A,PSMB9,EML4,TAF2,PPP2CA,KIF2A,RAD51C,CHMP4A,CDC16,DSN1,NSMCE2,H2AFX,PPP5C,TUBB,CSNK1D,BABAM1,CDCA3,BLM,RAB11A,MAD2L2,RFWD3,RPA2,CCNK,PSMD2,PTEN,CENPJ,PTPN11,PRC1,NAA50,GTSE1,CNOT6L,MSH6,SMC4,NUDC,PPP3CA,NEK7,JTB,TBRG4,ANAPC2,MACF1,KIF11,RPA1,KIF18A,POLE,TFDP1,PML,SSNA1,WDR62,ESPL1,ANAPC4,SSSCA1,POLA2,SKA3,GPR132,ENSA,CSNK2A1,SIRT2,KIF2C,BECN1,MAPK14,BIRC2,FANCI,PRNP,DST,RAB8A,NUP210,PCNA,RAB35,XRCC2,KIF22,MCMBP,CARM1,PLK1,RRM2,EZR,CDC6,PBRM1,BRCA1,ANLN,SOX4,RHEB,OPTN,CHD3,E2F4,PPM1G,CAB39,ZNF268,STK11,VPS4A,CHEK2,SASS6,PSMC1,PPP1R12A,PHB2,GORASP1,CENPF,LAMTOR3,RACGAP1,CRLF3,NUP205,DTL,RB1,CCP110,BANF1,TIMELESS,KNTC1,MCPH1,PSMA1,SEPT7,EIF4G2,DAPK3,RBM38,PSMC4,MASTL,HAUS8,TSC1,PCM1,CDC27,ODF2,CDCA5,NUP62,CCNB2,PRKAB1,SART1,CHMP2A,FOXM1,DYNLL1,SMARCA4,RRAGC,ORC1,OIP5,MDM2,PSMA6,KIF14,AKAP8,PPP6C,PRPF19,BIRC3,BTG2,TUBGCP5,PSMB7,NUP155,CHMP2B,TXNL4A,RAD54B,PSMD3,CEP55,XRCC3,CHMP4B,GAS2,REEP4,PPP2R2D,ZC3HC1,RAD51D,KIF3B,CTDP1,MCM10,KLHL21,RAE1,EYA1,CDT1,DCTN2,DBF4,NUP54,CDCA8,CDK11B,CSNK1A1,NCAPG,TUBGCP2,SAC3D1,FBXO5,STARD9,ARHGEF2,CENPM,ORC3,CAMK2G,GINS1,TGFB1,PPP1R9B,RHOA,ASPM,PRKDC,TOP3A,RANGAP1,WDR81,BORA,CDK11A,MFN2,UPF1,NEK1,BIRC5,E2F1,PKD2,CENPT,CHMP7,UBE2C,HRAS,TERF1 |
| 4.853e-37 | -83.62 | organelle organization | biological process | GO:0006996 | 3330 | 752 | 17256 | 2622 |
TMED7,RAB14,FGFR1OP,ADD1,KDM4A,HEXB,XIAP,GLUD1,CNTROB,MIS12,RPL23A,CDK5,NEK6,DNAAF2,RAD23B,AP1M1,PDS5B,DNM2,NUP153,RNF26,BAK1,PLK3,ERCC1,RHOBTB3,GABPA,EHMT1,WDHD1,MCL1,MIER2,SMC2,MCM2,RAB22A,GINS4,STOML2,BRMS1,RPS27A,LIMK1,AXIN1,MYO18A,OGT,MPV17,ATP6V0C,TFDP2,LONP2,AAAS,SLC25A33,SSRP1,NDUFV2,PHF23,RHOC,MUM1,DHX9,RAB23,TOP2B,HAUS4,EZH1,TMED3,ITGB5,HAUS2,CDC73,LMNA,MCTS1,ATG4A,CD59,PDXP,SMC3,FBXO7,NUP85,NSUN4,PPP6R1,NAGPA,TIMM8B,TSPYL4,RB1CC1,ZMYND11,MTA2,MTFR2,RPS10,MYBL2,MAP7D1,MTX1,RHOB,SETD3,TEX30,WIPI2,NDE1,ZNF830,CFAP20,RUFY3,SGF29,NUP58,ALS2,ZNF207,RHOG,UBR2,POC1A,CHD1L,PTTG1,ACTR3,ANK3,VTI1A,C5orf30,TPX2,MYH9,NUF2,INO80E,EFL1,PRKACA,STMN1,STAM,CLUAP1,AHCTF1,ATP2A2,SP100,SH3BP1,MTA1,NUP107,NSFL1C,SEPT11,RNF19A,CEP63,ATF2,CLN6,DCTN1,ATP6V1G1,SNX8,ULK3,PSRC1,FAM118B,KAT7,INTS13,RPL38,CIRBP,ATP6V0A1,NUSAP1,GORAB,NDUFA7,RAB1A,TAZ,PPP2CA,CHCHD3,KIF2A,PEX5,SEC61A1,CORO1C,NSMCE2,HIPK2,CAMKMT,PPP5C,PITRM1,TUBB,MZT1,TRAK1,JMJD6,ATG2B,ATP5F1B,WDR5,ETS1,IFT27,WRB,SAPCD2,GOLM1,RPA2,PDCD10,ADD3,SUV39H2,NDUFB4,HUWE1,PRDM4,NAA50,KANSL2,NAP1L4,GTF2H2,SPTAN1,NUDC,PDPK1,TCTEX1D2,TACC1,JTB,HEBP2,RAB3IP,PICALM,RPA1,KIF18A,POLE,CCDC6,PML,HMGB2,SSNA1,WDR45B,YWHAH,SNAPIN,AGRN,S1PR2,SEC16A,BIRC2,ATPAF1,TET3,RAB8A,PCNA,NUP210,TIMM23,XRCC2,NOC2L,ZFYVE27,MCMBP,MYBL1,TACC3,RYBP,PLK1,SEPT9,RBX1,BAZ2A,TLK1,EZR,PBRM1,UTP3,BRCA1,ANLN,STX16,RAB5B,USP21,OPTN,EPB41,DPYSL3,TRAM2,SEPT1,TIMM13,CHD3,E2F4,NAGLU,ACTB,DVL1,CLN3,POT1,NAA60,C2CD5,HJURP,PHB2,CENPF,NKD2,CTCF,KLC1,CHCHD2,RACGAP1,NCKAP1,RLF,ARID1B,RB1,VASP,CCP110,VMP1,MBD2,XPA,ARL6IP1,CTR9,PREB,TRAPPC9,LDB1,CAMSAP1,KRAS,RTF1,ARPC1A,BBS12,HAUS8,MBIP,PCM1,SNAP23,TBPL1,PRMT7,RUVBL2,ATP5F1A,CCNB2,UNC13C,BCCIP,USP7,NDUFA5,ARID2,NDUFAF2,DYNLL1,TOR1AIP1,ATP6V1B2,RPL11,OIP5,NRF1,ATP6V0B,KMT5C,BRPF3,ABRAXAS2,PIN1,TARDBP,CORO1A,LMAN1,TOP1MT,SAP30L,KDM3B,PPIF,ARHGAP17,MND1,CLCN3,BIRC3,PPT1,RAB7A,TUBGCP5,NUP155,DCLRE1C,KDM1B,CHMP2B,RPSA,USP36,RBL1,UBXN2B,TIMM17A,NDUFA11,CEP55,CHMP4B,XRCC3,NCOA1,H3F3A,RAD51D,PARD3,CTDP1,MTERF1,CDT1,CDCA8,SMC6,ARFIP2,HMGN3,CSNK1A1,NCAPG,TUBGCP2,STARD9,IRF4,NDUFV1,SS18L1,ABCD1,CENPM,PTGES3,POLR1B,PPAN,ACP2,RHOA,HMGN5,SNX2,PRKDC,ZMYM5,TOP3A,RANGAP1,PCGF1,RHOT2,CHCHD6,RAB18,SEC23IP,PDCD6,ATP6V1D,NEK1,BIRC5,L3MBTL3,SNAP29,E2F1,PKD2,TAF12,CHMP7,UBE2C,NUP188,H2AFZ,PDCD6IP,NDUFB6,CXXC1,TAP1,CCNB1,PARK7,KIFC1,MTFR1L,TAF5L,CISD2,CDC25B,MAST2,TFG,SMARCE1,DNMT1,SEH1L,USO1,ATG9A,AURKB,USP22,MCFD2,SLC25A5,RFC2,FOXRED1,PRIM1,ZMYM3,DOT1L,HHEX,WAS,KIF18B,BRD2,TMED10,RPS14,MAP4,EIF2D,ITGB1,PTPDC1,RRS1,RTN3,HDAC2,RECQL,MAPRE1,PRKAA1,DNAAF5,KIF23,CYCS,PMF1,SUPT7L,PSEN1,TMEM165,VPS25,NDUFS7,NPLOC4,JMY,SPAG5,CFLAR,NDUFS4,RTKN,NDUFAF6,TMEM250,ARPC5,SNX18,HDAC7,MSH2,ATP6V0A2,PIKFYVE,TNRC18,SYTL3,TMED2,TERF2,GCC2,DDX28,PRIM2,WDR1,SEPT8,GORASP2,ARID1A,TOMM40,GOSR1,KDM3A,PATL1,XRCC5,PI4K2A,SEC31A,GOLGA2,NSF,EPOP,ARAP1,PPP3R1,VCPIP1,CABIN1,YY1,PPP6R3,CDK2,CDKN2A,NDC1,DNMT3A,ATXN3,TRIP10,RAF1,SUZ12,RAC1,BCL2L1,MOAP1,TERF2IP,CCNA2,SHC1,KDM2A,TAP2,TP53BP2,CFL1,SAP30,ANKLE2,BRD4,RFC3,MKLN1,TAOK1,CUL3,ELP4,CDC23,POLG2,H2AFV,GAR1,TRIM28,EML4,CENPU,SUPT16H,RAD51C,HSPA4,CHMP4A,DSN1,SAFB,GOLGA8A,H2AFX,TRIM32,BEND3,EYA2,DYNC1LI2,CSNK1D,ATMIN,NDUFS1,TWNK,MECP2,BABAM1,SPDL1,BLM,RAB11A,HMG20A,MAD2L2,PIP5K1C,SLC25A36,NDUFA2,PTEN,CENPJ,PRC1,AXIN2,COPS7B,CNN2,CREB1,NDUFA3,MTX2,IFT46,PACS2,MSH6,SMC4,ZFP64,KAT2A,STRIP1,TMEM126B,NEK7,WDR18,RHOT1,KIF11,MARK2,CBX3,INF2,TMEM127,HGS,ATP5MC3,PRDX3,STX18,TFDP1,CCDC69,NDUFS5,WDR62,BRWD3,TAF6,ESPL1,PURA,DDB1,IPO4,POLA2,NPHP4,MTX3,NOP2,UBN1,NF1,KMT2E,UQCR10,KIF2C,SIRT2,AGFG1,TAF6L,BRIX1,BECN1,ATP5PF,MAP1LC3B,EDC3,DST,SYNM,CDC42,RAB35,ATG3,DPYSL2,RPF2,KIF22,NDUFB9,CARMIL1,ARID4A,CARM1,TIMM50,ELOF1,SRPK2,COPS8,NCK1,FOPNL,RIOX2,TMEM216,WDR82,PITPNB,KMT2C,ASF1B,CHAF1A,UBTF,PAF1,HSPB11,BRWD1,NIP7,TIMM29,ATXN2L,BAZ1B,CHEK2,ROCK1,VPS4A,CLU,COPS6,SASS6,ATP6V0E1,RPS15,PPP1R12A,GORASP1,CIB1,MEF2A,NUP205,BANF1,ZNF335,BCL2,KIFAP3,KNTC1,ZRANB1,MCPH1,ATP6V0D1,HP1BP3,ATP5IF1,RPL6,GBA,EIF2A,SEPT7,DAPK3,MASTL,NAP1L1,CDCA5,ODF2,SLC16A1,NUP62,YWHAZ,RBBP4,TMEM14A,SMARCD1,MBD1,WASF2,CHMP2A,CORO7,TOMM20,IMMT,ASH1L,FAM92A,SMARCA4,NSD3,TWF2,CHD1,MEAF6,MIEF1,HNRNPA2B1,ANKRD28,RRN3,ANKLE1,UBXN2A,BABAM2,SAR1A,KIF14,AKAP8,PPP6C,APOOL,F2R,ABI1,HTRA2,CHP1,FAM172A,DMAC2,PCGF6,WIPF1,TOR1AIP2,BICD2,ERBIN,NDUFB1,MBD3,PEF1,RAD54B,SURF4,HPS5,ANP32E,SMURF1,REEP4,BRD9,PPP2R2D,ABCA1,CBX4,TMEM33,DNAJC2,KIF3B,GCLM,GOLPH3L,RAE1,EYA1,SHPRH,DCTN2,SRGN,NUP54,TIMM21,PAWR,GFM2,FBXO5,KIF5B,FASTKD3,KLHL20,KMT5A,SEC24C,PELO,ANP32A,ARHGEF2,H2AFY,NDUFS8,ATG13,TTC17,FBL,MRPL11,STAT3,MICAL3,GINS1,TELO2,PPP1R9B,COA3,HMGN1,NASP,TIMMDC1,ASPM,HELB,MIER1,ATP2C1,COG1,RCOR1,WDR81,PRMT2,MEN1,ATP5MF,TFEB,MFN2,LEMD2,UPF1,ATAD2,ELMO1,KMT2B,CENPT,ATP6V1C1,TERF1 |
| 5.626e-37 | -83.47 | XPO1 (exportin 1) | protein interactions | 7514 | 1228 | 370 | 17029 | 2761 |
FGFR1OP,MAX,PNISR,ADD1,AP3M2,YTHDF3,GYG1,CNTROB,CCNB1,UBE2I,SYNRG,RBM4,PABPC4,MIS12,RPL23A,C14orf119,EEF2K,MTFR1L,SNUPN,AP1M1,AP2B1,CRY2,NUP153,CDC25B,ECD,SMARCE1,MLST8,SRP72,AATF,WDHD1,AURKB,MCM2,IWS1,MKNK1,RAD18,RPS14,AXIN1,C1orf109,PTPDC1,SMAD1,ARRB2,RTN3,NMD3,AAAS,PDCD4,SSRP1,CLSPN,POLR2K,TOP2B,HAUS4,HAUS2,COPG2,CDC73,COPB2,CNOT3,MCTS1,FBRS,RTKN,DDX56,EIF2S2,MEX3C,ZNRF2,SNX18,FBXO7,PPP4R1,RTCB,PCYT2,CPSF4,PABPC1,PPP6R1,EIF5A,EIF3L,ETV3,FOXK1,RPS10,KCTD20,SEPT8,BCLAF1,GORASP2,SRSF5,C9orf40,PATL1,ABCF1,MAP2K2,NCDN,SEC31A,MAGED2,EPRS,SERTAD2,GOLGA2,ETS2,TCOF1,PPP6R2,PPP6R3,CFAP20,NDE1,PDLIM5,ZC3HAV1,RWDD1,RAF1,EIF3D,ACTR3,PTTG1,WDTC1,C5orf30,AP1B1,PRKACA,GNB2,PAIP2,TERF2IP,SHC1,UTP18,TBC1D14,UBA5,NUP107,NABP1,TNPO2,CDKN1B,ANAPC7,ATF2,CDKN2AIP,PSRC1,CDC123,ERF,EID1,KAT7,MAP4K4,RNPS1,MEF2D,CDC23,GSTCD,AP4E1,GIGYF1,MAT2A,DDX17,ANKZF1,PEX5,STAT1,RWDD4,RBMS1,TICAM1,DMWD,PPP5C,COIL,CSNK1D,TUBB,LRCH1,PRPF4B,RPS2,SRSF6,TCF3,TRAK1,AKT1S1,WDR5,FOXO3,CCDC28A,HEATR5B,SAPCD2,PNO1,GTF2F1,RBM17,MAT2B,RFWD3,CAPN2,ADD3,HUWE1,ARHGEF1,GTSE1,DCP1A,ANXA5,UPF2,NAP1L4,HNRNPM,PDPK1,STAU1,DENND1B,DENND4C,RPL8,FBXO9,PICALM,POLR2A,SMAP2,CIP2A,SH3BP5,NUCB1,KEAP1,TTLL4,GPS2,CCDC6,MFAP1,HNRNPH3,PITX1,MAPK6,DDX5,WDR91,YWHAH,ESPL1,ANAPC4,BYSL,POLA2,ZBED3,DDX47,COPA,GPBP1L1,CSNK2A1,UBE2Z,SIRT2,AGFG1,SEC16A,BECN1,KCMF1,EDC3,LIN9,AP3S2,ATG3,NOC2L,EIF5,SEPT9,WDR82,BRCA1,EAF2,PRPSAP1,LUC7L,USP21,PAF1,EIF4ENIF1,TBC1D17,CDCA4,SPATA2,E2F4,ARRDC1,PRPF4,DVL1,CLU,CLN3,GLCCI1,TSTD2,NUMB,TBC1D12,PARP12,ZCCHC8,GORASP1,FAM53C,EPN1,MEF2A,THRAP3,XPO7,CNOT11,RAPGEF6,SRRT,TNS3,VASP,CCP110,XPA,CTR9,YBX1,MAML1,HP1BP3,NIPSNAP1,POLR2I,TRAFD1,TSTA3,DCAF8,UTP15,RPL6,KRAS,SEPT7,ARPC1A,EIF4G2,IRF5,HAUS8,GNAS,NAP1L1,CDC27,FAM122A,NUP62,YWHAZ,RUVBL2,SNRNP70,CCNB2,ECPAS,NIPSNAP2,TCF12,CHMP2A,CYLD,FAM207A,COPE,PMS2,IRF3,ORC1,TWF2,C2orf68,CSDE1,MDM2,ABRAXAS2,PPP6C,RPAP1,AHCYL1,UTP4,SCYL3,STRAP,DVL2,POC5,CHP1,KDM3B,NXT1,POLR2G,SMU1,FRAT2,BICD2,ERBIN,CHMP2B,TOLLIP,RPS9,RPSA,EIF3H,SRSF1,SUGP1,DHX16,TAB2,CEP55,AP1S1,XRCC3,SMURF1,PDCD2L,SMAD4,UNK,SMAP1,PDAP1,CDT1,SCYL1,DBF4,CDCA8,GGA2,AP3S1,CSNK1A1,PAGR1,TUBGCP2,SCYL2,WRNIP1,KLHL20,SEC24C,PELO,ANP32A,FBL,RPAP3,SAMD4B,TELO2,PRKAR1B,TUFM,RANGAP1,WDR81,BORA,SNRPA,TFEB,CNOT9,UPF1,NEK1,PDCD6,TRIM26,SEC23IP,BIRC5,L3MBTL3,ZNF330,SNAP29,TFE3,TAF12,RBPJ,CHMP7,TERF1 |
| 7.932e-37 | -83.12 | SCGGAAGY_V$ELK1_02 | MSigDB lists | SCGGAAGY_V$ELK1_02 | 1112 | 328 | 17377 | 2626 |
TSC2,CXXC1,YTHDF3,DHX8,CNTROB,MIEN1,SYNRG,PABPC4,FBXO22,C14orf119,USF1,DNAAF2,SRSF4,AP1M1,TAF5L,ECD,PRADC1,DNMT1,ZNF800,PCBP2,NOL12,ERCC1,NRAS,AATF,NSUN2,MRPL43,MCL1,NUTF2,SLC25A5,RFC2,FOXRED1,STOML2,KRIT1,WAS,RPS14,PRDX5,MRPL27,MLYCD,UQCRH,RRS1,DDX42,NXT2,COX5B,HSPH1,MAPRE1,MUT,POLR2K,PHF23,GGA1,ZNF79,MYL6B,CNOT3,WDR48,MCTS1,FAM192A,RNF121,SLC31A1,EFTUD2,TNPO3,MRPL40,ANKHD1,PABPC1,MORC3,EIF5A,EIF3L,GCC2,PIGT,RB1CC1,WDR1,MTA2,PGS1,TOMM40,C9orf40,SEC31A,MAGED2,PDLIM1,USP32,VCPIP1,TCOF1,PDLIM5,MRPL3,TRIM41,RAB11B,SF3B1,TPX2,MON1B,KLHL18,TBC1D13,BCL2L1,POMP,INO80E,AP1B1,C2orf49,PAIP2,FBXL6,SHC1,ATP2A2,MTMR4,UBA5,NUP107,CGGBP1,ATP13A1,CDC123,KAT7,LYRM1,RNPS1,DNAJA1,GAR1,DHX57,SUPT16H,AMZ2,HSPA4,SEC61A1,DDOST,ACYP1,RAB24,CORO1C,GEN1,XRCC4,ZBTB11,NDUFS1,TMBIM4,SRSF6,TRMT6,CDCA3,CBLL1,AKT1S1,UBE4A,BLM,HMG20A,CCDC28A,FBXO3,ERH,FUT8,DCP1A,LTN1,RPL19,SLC38A10,COPS7B,CNPY3,MTX2,TMX1,LYPLA2,NUDC,TTPAL,ZFP64,ZNF512,RFXANK,MRPS10,LLPH,DDX39A,MARK2,SMAP2,ZNF180,TMEM127,RPL32,PPP1R11,DDX5,BRWD3,ANAPC4,IPO4,COX15,IER2,DDX47,NF1,TRIM11,DNAJC24,UBE2Z,EBNA1BP2,SIRT2,SND1,COMMD5,BECN1,CUTC,GIT2,UBLCP1,ZER1,KRR1,BCAT2,RAB8A,TIMM23,ATG3,RCSD1,PHTF1,NOC2L,ZFYVE27,SLC35C2,MCMBP,OGG1,MTPN,ASB6,ARID4A,VPS13B,CDC37,DPM1,HARS,SNRPB,TLK1,UTP3,KRTCAP2,DHX15,C1orf122,NECAP2,RPL37,TBC1D17,AGPAT2,GRIPAP1,E2F4,SH3GLB2,ACTB,GALNT10,CLN3,TSTD2,PSMC1,NAA60,ZCCHC9,TMUB1,PHB2,UFC1,UBXN1,EPN1,CDK13,DNAJB1,TTF1,PRPF18,MED8,CCP110,VMP1,BANF1,PPIL2,MEA1,CTR9,GLE1,SLC12A2,TSTA3,RPL6,EIF2AK1,MAP4K3,SEPT7,PSMC4,RXRB,MASTL,EVC2,MOSPD3,PALB2,ODF2,PITPNA,NAA20,RBBP4,EHD4,WASF2,PRKAB1,SART1,CHMP2A,TOMM20,RPLP2,TRAF7,CHERP,XAB2,COPE,PCBP1,RPL11,RAD23A,USP5,SEC11A,SAP130,PSMA6,SAR1A,PPME1,PARL,RPAP1,CSTF1,PRPF19,SLC39A9,KDM3B,RAB7A,SMU1,PSMB7,NUP155,DCLRE1C,HERPUD2,ARL5B,EIF3H,BTBD1,SUGP1,CEP55,PROSER1,TMEM101,AP2S1,CHID1,RAD51D,CWC25,TMEM33,RRP15,PDAP1,ARFIP2,SMC6,BZW2,PIP4K2A,PTPN2,GART,CTNNBL1,SEC24C,PPIG,SLC25A1,PPAN,B3GALT6,PHF20L1,MLEC,RHOA,ACP2,NASP,TIMMDC1,BTAF1,PPP1R21,ATP2C1,METTL5,MIER1,TUFM,SCFD2,PNPLA8,PCGF1,ATP6V1D,PDCD6,SEC23IP,COX8A,ZRANB2,RPS6KC1 |
| 8.080e-37 | -83.11 | SIRT7 (sirtuin 7) | protein interactions | 51547 | 668 | 240 | 17029 | 2761 |
PDCD6IP,NUP188,COPA,NOP2,NF1,PHRF1,YTHDC2,DHX8,CSNK2A1,EBNA1BP2,SND1,OAT,BRIX1,SEC16A,MYEF2,PABPC4,FANCI,RPL23A,SF3B2,KRR1,DST,UTP25,PSMD1,NUP210,NOL11,DPYSL2,INTS1,SRSF4,PDS5B,NOC2L,DNM2,AP2B1,RPF2,NUP153,DNMT1,FTSJ3,CCAR1,USP34,SRP72,SNRNP200,AATF,BAZ2A,NSUN2,MKI67,HNRNPF,DDX20,DIDO1,PBRM1,PRKRA,MAK16,DHX15,STOML2,ZMYM3,GEMIN5,UBTF,AHNAK,RPS14,TPP2,PPM1G,MAP4,U2SURP,IARS2,ATXN2L,BAZ1B,RRS1,RPS26,PFKP,CAPN1,HDAC2,ANXA11,DDX42,RPS15,RECQL,EWSR1,ZCCHC8,CENPF,RPL15,KIF23,CTCF,NCKAP1,XPO7,PARN,TTF1,COPG2,NUP205,COPB2,LMNA,DDX56,MCM5,RBM34,ATIC,RTCB,MSH2,GEMIN4,ALDH18A1,MVP,ANKHD1,PABPC1,HP1BP3,EIF3L,PRRC2A,MTA2,TEX10,ACSL3,SUGP2,RPS10,RPL6,UTP15,GTPBP4,RPS24,ARID1A,PLEC,SRSF5,FXR1,ABCF1,SLTM,XRCC5,NAP1L1,PCM1,SYNCRIP,CCDC86,RBM25,RBMX,ACLY,TCOF1,PPP6R3,SNRNP70,RBBP4,ECPAS,ZC3HAV1,USP7,SART1,KARS,IMMT,FAM208B,RPLP2,CHERP,URB2,XAB2,SF3B1,EIF3D,MAGED1,ACTR3,MYH9,SMARCA4,AP1B1,SDHA,APP,CHD1,USP5,ANKRD28,CSDE1,MDM2,AHCTF1,ATP2A2,STRBP,NVL,UTP18,KIF14,NUP107,RPN2,AQR,RBM15,UTP4,CCT2,CRNKL1,SMU1,RPL38,NUP155,DNAJA1,VDAC1,RPSA,DHX57,AFDN,NSA2,ATP1A1,HSPA4,DHX16,TBL3,RPLP1,H2AFX,FUS,BEND3,USP11,LTA4H,ZBTB11,PDCD11,COIL,PRPF4B,NIFK,RPS2,NDUFS1,TRIP12,ANXA6,NKRF,BLM,KRI1,KIF5B,PSMD2,GART,HUWE1,SEC24C,DDX31,RPL19,FBL,TTLL12,MSH6,MYO5A,SMC4,SPTAN1,STAU1,DDX24,ZNF512,PRKDC,WDR18,TUFM,RPL8,RANGAP1,BMS1,MACF1,SYMPK,ZFR,POLR2A,CBX3,DDX23,UTP20,UPF1,ATAD2,POLE,OSBPL8,KBTBD7,LRPPRC,ACAT1,KHSRP,SRSF3,PGAM1,IPO4,DDB1,BYSL,DDX52 |
| 9.757e-37 | -82.92 | mitotic cell cycle | biological process | GO:0000278 | 696 | 237 | 17256 | 2622 |
POLA2,FGFR1OP,NUP188,MAX,SKA3,PDCD6IP,GPR132,XIAP,ENSA,CUL1,CNTROB,KIF2C,CCNB1,BECN1,BIRC2,FANCI,MIS12,KIFC1,CDKN2C,RAB8A,PCNA,NUP210,NEK6,RAB35,XRCC2,PDS5B,DNM2,KIF22,NUP153,CDC25B,MYBL1,SEH1L,TACC3,CARM1,CDC5L,PLK1,PLK3,SEPT9,PBK,KIF15,MRNIP,WDHD1,RRM2,CDC6,SMC2,PBRM1,AURKB,BRCA1,ANLN,MCM2,SOX4,OPTN,PRIM1,SEPT1,KIF18B,RPS27A,E2F4,MAP4,ITGB1,CHEK2,VPS4A,RRS1,TFDP2,AAAS,MAPRE1,CLSPN,PPP1R12A,PHF23,RHOC,CENPF,RRM1,CIB1,KIF23,TOP2B,HAUS4,RACGAP1,CNOT11,CRLF3,HAUS2,LMNA,NUP205,CNOT3,SPAG5,RTKN,TMEM250,RB1,SMC3,CCP110,SNX18,MCM5,BANF1,MSH2,FBXL7,KNTC1,MCPH1,NUP85,PRIM2,MYBL2,SEPT8,SEPT7,RHOB,HAUS8,MASTL,PCM1,CDC27,GOLGA2,ODF2,CDCA5,VCPIP1,NUP62,CNOT6,NDE1,ZNF830,CDK2,CCNB2,NUP58,CDKN2A,BCCIP,ZNF207,NDC1,CHMP2A,DNMT3A,FOXM1,DYNLL1,POC1A,ANK3,TPX2,NUF2,ORC1,BCL2L1,PRKACA,STMN1,CCNA2,MDM2,ABRAXAS2,KIF14,PPME1,AKAP8,NUP107,PPP6C,NABP1,SEPT11,CDKN1B,CEP63,ATF2,CFL1,DCTN1,ANKLE2,PSRC1,BRD4,BIRC3,ERF,BTG2,INTS13,TAOK1,CUL3,TUBGCP5,NUSAP1,NUP155,PKMYT1,CHMP2B,CDC23,AZI2,EML4,TAF2,PPP2CA,KIF2A,CDC16,CHMP4A,DSN1,CEP55,CHMP4B,PPP5C,REEP4,PPP2R2D,CSNK1D,TUBB,CTDP1,KIF3B,MCM10,MZT1,MECP2,RAE1,CDT1,DCTN2,CDCA8,NUP54,DBF4,BLM,SPDL1,CDK11B,NCAPG,RAB11A,TUBGCP2,MAD2L2,SAPCD2,FBXO5,RFWD3,RPA2,CENPJ,PTPN11,PRC1,NAA50,NABP2,GTSE1,ARHGEF2,ORC3,CNOT6L,CAMK2G,SMC4,TGFB1,GINS1,PPP3CA,RHOA,NASP,PRKDC,JTB,MEN1,BORA,KIF11,CDK11A,RPA1,CNOT9,KIF18A,POLE,BIRC5,TFDP1,E2F1,PML,SSNA1,CENPT,WDR62,UBE2C,CHMP7,HRAS,ESPL1,SSSCA1 |
| 2.113e-36 | -82.14 | catalytic complex | cellular component | GO:1902494 | 1402 | 382 | 18223 | 2701 |
MAX,NDUFB6,CXXC1,PIGQ,DHX8,CUL1,CCNL2,CCNB1,UBE2I,POLR3K,PARK7,CALM2,USF1,PSMD1,NSRP1,RAD23B,SUCLG2,TAF5L,SPTSSA,SMARCE1,ZNRD1,CDC5L,ERCC1,GNG7,HNRNPF,TOPORS,SUPT20H,USP22,DCUN1D5,CCNF,FOXRED1,CLNS1A,PRIM1,BRMS1,RAD18,STT3A,PSMD8,WDR4,OGT,DHTKD1,UQCRH,KLHL42,FBXL3,HDAC2,NDUFV2,POLR2K,PRKAA1,DHX9,RRM1,STRN4,KCTD17,NDUFA4,CYCS,EZH1,SUPT7L,PSMD9,METTL3,CDC73,NDUFS7,YY1AP1,CFLAR,NDUFS4,RPN1,EXOSC7,KLHL5,INTS7,HDAC7,DAD1,FBXO7,EFTUD2,PPP4R1,FBXL7,CYC1,GNAI2,PABPC1,PHKG2,PHF10,PRIM2,PIGT,RB1CC1,MTA2,SF3B6,TEX10,EXOSC9,ARID1A,PKM,SF3A2,PSMB3,TWISTNB,FNTA,POLR2J,EPOP,RBMX,DCAF11,PPP3R1,PTAR1,APPL2,YY1,MAP3K5,RNF14,CDK2,SGF29,TRERF1,UBR2,SUZ12,SF3B1,KLHL18,INO80E,SDHA,ANKIB1,PHC2,CCNA2,UCHL5,DDA1,INTS12,CDKN1B,ANAPC7,RNF19A,AQR,GPD1L,NAA35,RPRD1B,CDK12,DCTN1,SAP30,SHOC2,POLR2L,KAT7,CRNKL1,POLR2D,CUL3,ELP4,EDF1,NDUFA7,DNAJA1,CDC23,PSMB9,GAR1,ERC1,MAT2A,TAF2,PPP2CA,CDC16,HINT1,DDOST,PPP2R5A,DGCR8,NSMCE2,SEL1L,TICAM1,SNRPG,DYNC1LI2,PRPF4B,NCOR2,NDUFS1,TRMT6,CBLL1,BRAP,GMCL1,UBE4A,WDR5,MAD2L2,NEXMIF,WWP2,GTF2F1,PPP1R3B,MAT2B,CCNK,ERH,PSMD2,NDUFA2,NDUFB4,PRDM4,NAA50,KANSL2,OSTC,NDUFA3,FBXL19,GTF2H2,HNRNPM,PPP3CA,ZFP64,KAT2A,TCTEX1D2,FBXO9,ANAPC2,FADD,POLR2A,FBXO21,GNA12,KEAP1,MAGT1,POLE,PRDX3,KHSRP,PPP1R11,DDX5,NDUFS5,WDR62,TAF6,ANAPC4,DDB1,MIB2,POLA2,CCNC,DCAF15,UQCR10,PPP1R15B,RBM8A,MCCC1,CSNK2A1,TAF6L,SNRPD3,BECN1,SF3B2,ZER1,EIF4A3,INTS1,ATG3,METTL14,PIK3R2,POP7,GPATCH1,NDUFB9,TCEA1,WDR41,METTL1,RPP25,SNRNP200,EXOSC6,DPM1,RBX1,NCK1,SNRPB,VHL,RRM2,WDR82,UBE2V1,BRCA1,PBRM1,PRKRA,KMT2C,KRTCAP2,PAF1,CHD3,CRCP,CAB39,ACTB,SINHCAF,PSMC1,DCAF5,NSMCE4A,PPP1R2,PPP1R12A,ZCCHC8,ZNF768,UBXN1,CDK13,PPP3CB,ARID1B,DTL,RB1,MED8,MED10,PYURF,MBD2,BUD31,ZNF335,CTR9,UBE3C,POLR2I,DCAF8,PSMA1,RTF1,UBE4B,SYVN1,APPL1,CAND1,PSMC4,GNAS,SDHB,MBIP,SYNCRIP,ORMDL2,CDC27,KLHL15,PRPS2,TBPL1,RUVBL2,NAA20,RBBP4,ECPAS,PDSS2,SMARCD1,BCCIP,NDUFA5,PRKAB1,SART1,MPHOSPH8,TRAF7,XAB2,DYNLL1,SMARCA4,MEAF6,RAD23A,HNRNPA2B1,SEC11A,SAP130,FARSA,PDK2,PSMA6,BABAM2,BRPF3,EXOSC1,RPN2,SAP30L,GM2A,SPSB3,HTRA2,DNAL4,PRPF19,UBQLN4,POLR2G,PGGT1B,PSMA8,PPIE,DMAC2,PSMB7,PCGF6,OGDH,NDUFB1,MBD3,PEF1,PDHX,BTBD1,SRSF1,ATP1A1,IDE,HNRNPR,PSMD3,NDUFA11,ANP32E,PPP2R2D,CBX4,INTS2,CTDP1,GCLM,CDC40,KLHL21,DCTN2,AGO2,SMC6,DCUN1D4,PAGR1,NDUFV1,KLHL20,CWC27,H2AFY,SS18L1,NDUFS8,ATG13,POLR1B,TXNL1,PPP1R9B,DCAF6,RPRD1A,HELB,ABCF2,POLR3GL,PPWD1,MEN1,DDX23,HSPA1B,PDCD6,GOLGA7,KBTBD7,KMT2B,TAF12,SPCS3,UBE2C,GCSH,ZSWIM6 |
| 3.362e-36 | -81.68 | TIEN_INTESTINE_PROBIOTICS_24HR_UP | MSigDB lists | TIEN_INTESTINE_PROBIOTICS_24HR_UP | 527 | 195 | 17377 | 2626 |
LYRM4,NUP188,HNRNPAB,NDUFB6,RBM8A,TMEM109,TGOLN2,PLXNA1,SNRPD3,CCNB1,OAT,POLR3K,CMTM6,RAB8A,PCNA,PSMD1,CDC42,EIF4A3,TIMM23,SIVA1,ATP13A3,RP2,DNMT1,TRIM14,SEH1L,PLK1,MIOS,HARS,RBX1,RAD51AP1,GMFB,RRM2,WDR82,ARHGDIB,ICMT,MCM2,CBFB,RFC2,DHX15,KRIT1,MAP3K4,TIMM13,HSPB11,NIP7,LUC7L3,IARS2,PSMC1,ATP6V0E1,NXT2,NDUFV2,RECQL,MRPL9,HJURP,MRPS2,CENPF,DHX9,RRM1,KIF23,ASAH1,RACGAP1,TOP2B,PXMP2,LYRM2,SRRT,NUP205,SPAG5,GNS,SNRNP25,TNS3,SUB1,EXOSC7,INPP5A,MCM5,RBM34,EI24,GEMIN4,LPCAT1,NUP85,TIMM8B,CREG1,PGS1,DHX29,ERLIN1,AMD1,BCLAF1,NFATC2IP,SRSF5,RDH11,SYNCRIP,CCDC86,NSF,DCK,ACLY,TMEM14A,ZC3HAV1,USP7,NDUFA5,CKLF,FOXM1,CAST,DYNLL1,PTTG1,UROD,STARD7,SLC25A44,SNN,SAFB2,COMMD8,PAIP1,PSMA6,CCNA2,SAR1A,KIF14,DUT,NUP107,TARDBP,CHTOP,GM2A,PPIF,RFC3,POLR2L,EID1,CDC123,MAP4K4,PSMB7,SLBP,DNAJC9,PFKFB3,HTATIP2,NUSAP1,CADM1,DNAJA1,NDUFB1,H2AFV,SHCBP1,PDHX,FKBP3,SRSF1,SUPT16H,PON2,ACYP1,ANP32E,SNRPG,USP11,H3F3A,BRD9,RRP15,KLHL21,BABAM1,DBF4,HMGN3,UBE4A,GGA2,REEP5,WRB,SAC3D1,FBXO5,EBP,FASTKD3,FBXO3,PSMD2,ERH,NDUFA2,AHSA1,PRC1,GTSE1,TAGLN2,TPCN1,MSH6,HNRNPM,IMPA2,SLC25A1,SMC4,NUDC,GINS1,DCAF6,TK1,NASP,MRS2,ATP2C1,TBRG4,FBXO9,ADSL,KIF11,PICALM,RPA1,GOLGA7,HNRNPH3,DBI,LRPPRC,SRSF3,NR2F2,PGAM1,ESPL1,DDX52 |
| 5.929e-36 | -81.11 | MORF_EIF3S2 | MSigDB lists | MORF_EIF3S2 | 233 | 116 | 17377 | 2626 |
SRM,TOMM20,IMMT,H2AFZ,NUP188,HNRNPAB,EIF3D,SUMO2,STARD7,UBE2I,GNB2,PARK7,PABPC4,RAD23A,HNRNPA2B1,IARS,DUT,PIN1,TXLNA,CS,MRPS27,TCEA1,PDIA6,DNMT1,SRP72,CCT2,DEAF1,SNRNP200,AATF,PPIE,PSMB7,RNPS1,VDAC2,NDUFA7,PKMYT1,MCM2,VDAC1,SLC25A5,TXNL4A,SERP1,RHEB,EIF3H,CLNS1A,CHAF1A,NSA2,EIF3K,ALG3,DAP3,DDOST,HNRNPR,TBL3,TIMM17A,SAFB,PPM1G,BAZ1B,UQCRH,HDAC2,SSRP1,PPIB,MRPL9,PHB2,CYCS,SLC4A2,XPO7,AP3S1,EBP,RPA2,PSMD2,RPN1,NDUFV1,DNAJC8,EIF2S2,HUWE1,CAPZA1,YBX1,PTGES3,NAP1L4,CYC1,FBL,LDHB,NUDC,IFRD1,MLEC,POLR2I,PRKDC,WDR18,ILF3,TUFM,LDHA,PSMA1,DCTD,DDX39A,EIF4H,SF3A2,MAP2K2,SNRPA,TARS,POLR2A,XRCC5,CBX3,SDHB,EPRS,NAP1L1,CSK,PRPS2,ACLY,LRPPRC,IMPDH1,MDH1,TCOF1,GPI,RUVBL2,NDUFS5,IDH3B,CDK2,PTDSS1 |
| 2.230e-35 | -79.79 | U2AF2 (U2 small nuclear RNA auxiliary factor 2) | protein interactions | 11338 | 382 | 163 | 17029 | 2761 |
HNRNPAB,ST13,CUL1,GLUD1,SND1,RBM4,PARK7,PABPC4,SF3B2,KIFC1,PA2G4,PCNA,EIF4A3,GLIS2,GOT2,SRSF4,KHDC4,RPF2,TRA2B,LRRC59,CCAR1,SRSF10,CDC37,SRPK2,CDC5L,SNRNP200,SEPT9,LAP3,HNRNPF,EZR,ARHGDIB,ESYT1,MCM2,SLC25A5,LUC7L,DHX15,EIF3A,EPB41,AHNAK,SMAD2,U2SURP,RRS1,FUBP1,PPIB,HSPH1,EWSR1,MAPRE1,GMFG,ZCCHC8,PHB2,DHX9,CERK,RPL15,THRAP3,LMNA,RPN1,ATIC,EFTUD2,YBX1,MVP,GNAI2,PABPC1,LUC7L2,EEF1D,TERF2,SRSF11,EIF5A,WDR1,SF3B6,RPL6,PSMA1,RPS24,BCLAF1,SRSF5,SEPT7,PKM,EIF4H,CCT8,MATR3,SF3A2,CAND1,EPRS,SYNCRIP,RBMX,COX7A2L,YWHAZ,GPI,SNRNP70,HNRNPDL,SART1,SARNP,CHERP,MDH2,SF3B1,SUZ12,POC1A,PCBP1,HNRNPA2B1,MDM2,PIN1,TARDBP,CORO1A,TALDO1,CHTOP,PDIA6,DVL2,CFL1,PRPF19,CCT2,RAB7A,PPIE,RNPS1,CUL3,VDAC2,ATXN1,NUSAP1,PRPF3,VDAC1,TRIM28,SRSF1,DDX17,SUGP1,DAP3,HINT1,CLK3,HNRNPR,SAFB,STAT1,TUBB,ANXA6,PDAP1,SRSF6,FLOT1,TKT,CHIC2,JMJD6,PSMD2,HUWE1,ANP32A,ANXA5,TAGLN2,CNN2,FBL,S100A6,HNRNPM,SPTAN1,RHOA,PRKDC,PSPC1,ILF3,TUFM,RANGAP1,SNRPA,PRDX1,POLR2A,UPF1,KHSRP,HMGB2,DDX5,ZRANB2,SRSF3,TERF1,IFI16 |
| 3.695e-35 | -79.28 | GO_RNA_PROCESSING | MSigDB lists | GO_RNA_PROCESSING | 771 | 250 | 17377 | 2626 |
DDX47,NOP2,THOC1,PHRF1,YTHDC2,RBM8A,ALKBH5,DHX8,USP39,EBNA1BP2,SNRPD3,RBM4,PABPC4,SF3B2,KRR1,PAPOLA,RPL23A,PA2G4,SNUPN,NOL11,EIF4A3,NSRP1,METTL14,INTS1,TRMU,SRSF4,POP7,GPATCH1,RPF2,TRA2B,FTSJ3,CCAR1,PCBP2,SRPK2,CDC5L,SRSF10,METTL1,RPP25,EXOSC6,SNRNP200,SNRPB,NOL8,NSUN2,HNRNPF,DDX20,SREK1,UTP3,PRKRA,LUC7L,MAK16,DHX15,CLNS1A,IWS1,PAF1,GEMIN5,RPL37,SMAD2,RPS27A,LUC7L3,RPS14,WDR4,U2SURP,PQBP1,PRPF4,RNASEL,RRS1,OSGEPL1,SMAD1,RPS26,SMNDC1,GEMIN7,CTU2,RPS15,PRPF38B,ZCCHC8,POLR2K,DHX9,RPL15,CDK13,THRAP3,PRPF39,PDCD7,SRRT,METTL3,CDC73,PRPF18,RAVER2,SNRNP25,DDX56,EXOSC7,INTS7,EFTUD2,BUD31,ZNF326,YBX1,RBM3,GEMIN4,CPSF4,NSUN4,PABPC1,LUC7L2,SRSF11,POLR2I,AGGF1,DHX29,TEX10,SUGP2,TYW1,UTP15,RPS10,RPL6,RPS24,EXOSC9,SRSF5,SF3A2,RBM38,RPL36,RBM25,SYNCRIP,POLR2J,RBMX,TYW5,PRMT7,SNRNP70,TSEN15,CDKN2A,KARS,SART1,SARNP,TP53RK,RPLP2,CHERP,IVNS1ABP,SF3B1,XAB2,LAGE3,RRAGC,C2orf49,PRKACA,PCBP1,APP,RPL11,HNRNPA2B1,RBM23,ZNF473,DUS4L,UTP18,GRSF1,UBA5,EXOSC1,INTS12,TARDBP,AQR,CHTOP,AHCYL1,RBM15,ZC3H3,STRAP,CDK12,PRPF19,CSTF1,RPL29,RPL35,POLR2L,POLR2G,PPIE,RNPS1,POLR2D,CRNKL1,RPL38,METTL2A,SLBP,ATXN1,PRPF3,BUD13,GAR1,TXNL4A,RPS9,DHX57,RPSA,SRSF1,DDX17,NSA2,PPP2CA,SUGP1,DUS3L,HNRNPR,LSM6,DHX16,DGCR8,TBL3,RPLP1,FTSJ1,RBMS1,SNRPG,FAU,PDCD11,CSNK1D,PRPF4B,INTS2,CDC40,RPS2,SRSF6,TRMT6,JMJD6,PNO1,RRP36,GTF2F1,RBM17,GTPBP3,DNAJC8,CTNNBL1,RPL17,CWC27,PPP1R8,PPIG,GEMIN6,RPL19,CNOT6L,ERI3,FBL,GTF2H2,HNRNPM,RBM15B,YTHDC1,PPP1R9B,HELB,PSPC1,WDR18,RPL8,BMS1,PPWD1,RPL27A,DDX39A,SYMPK,TSR2,SNRPA,POLR2A,DDX23,UTP20,RPL32,HNRNPH3,KHSRP,ZRANB2,DUSP11,DDX5,SRSF3,BYSL,TYW1B,DDX52 |
| 6.736e-35 | -78.68 | MORF_BUB3 | MSigDB lists | MORF_BUB3 | 265 | 124 | 17377 | 2626 |
SRM,POLA2,KARS,IMMT,H2AFZ,NUP188,HNRNPAB,CHERP,DYNLL1,STARD7,STMN1,SDHA,PARK7,PABPC4,RAD23A,SF3B2,CALM2,HNRNPA2B1,PCNA,IARS,GOT2,DUT,CS,MRPS27,TARDBP,TCEA1,PDIA6,DNMT1,CCT2,SNRNP200,AATF,PPT1,PPIE,PSMB7,VDAC2,SLBP,DNAJC9,GLO1,AURKB,MCM2,VDAC1,H2AFV,TXNL4A,SERP1,TRIM28,RHEB,CHAF1A,SRSF1,EIF3K,DAP3,DDOST,HNRNPR,PSMD8,SAFB,PPM1G,BAZ1B,UQCRH,HDAC2,SSRP1,MAPRE1,MRPL9,SCAMP3,PHB2,RRM1,CYCS,XPO7,AP3S1,HDDC2,NDUFS4,RPA2,NDUFV1,EIF2S2,SMC3,DNAJC8,AHSA1,MCM5,SEC24C,CAPZA1,MSH2,PTPN11,EI24,TNPO3,ANP32A,PTGES3,CYC1,FBL,HNRNPM,NUDC,IFRD1,POLR2I,NASP,PRKDC,NSDHL,ILF3,TUFM,DCTD,RANGAP1,DDX39A,EIF4H,SF3A2,MAP2K2,SNRPA,TARS,XRCC5,CBX3,SDHB,EPRS,PRDX3,CSK,RBMX,TFDP1,PRPS2,ACLY,LRPPRC,KHSRP,IMPDH1,MDH1,SRSF3,RUVBL2,NDUFS5,RBBP4,CDK2,PTDSS1,ESPL1 |
| 8.819e-35 | -78.41 | MORF_RAD23A | MSigDB lists | MORF_RAD23A | 330 | 142 | 17377 | 2626 |
POLA2,H2AFZ,NUP188,HNRNPAB,PARK7,PABPC4,SF3B2,KIFC1,CALM2,GOT2,HADHB,TCEA1,DNMT1,SRP72,DEAF1,SNRNP200,AATF,MCM2,DHX15,RHEB,KRIT1,PPM1G,BAZ1B,UQCRH,PIEZO1,HDAC2,SMNDC1,NDUFV2,MAPRE1,MRPL9,PHB2,CYCS,XPO7,NUP205,NDUFS4,RPN1,EIF2S2,CAPZA1,EI24,TNPO3,CYC1,IFRD1,POLR2I,WDR1,NSDHL,DCTD,EIF4H,SF3A2,MAP2K2,XRCC5,SDHB,EPRS,CSK,RBMX,PRPS2,ACLY,MDH1,RUVBL2,RBBP4,PTDSS1,KARS,CHMP2A,TOMM20,IMMT,CHERP,DYNLL1,ACTR3,COPE,SUMO2,STARD7,LAGE3,BCAP31,SDHA,GNB2,RAD23A,HNRNPA2B1,FARSA,IARS,DUT,CS,TARDBP,PDIA6,PPIF,CCT2,PPT1,CDC123,PPIE,PSMB7,VDAC2,RNPS1,DNAJC9,SLBP,GLO1,NDUFA7,VDAC1,TXNL4A,H2AFV,TRIM28,SERP1,EIF3H,SRSF1,EIF3K,CDC16,DDOST,HNRNPR,SAFB,TBL3,AP2S1,SCAMP3,AP3S1,HDDC2,DNAJC8,NDUFV1,PPIG,SEC24C,AHSA1,PTPN11,ANP32A,NDUFS8,PTGES3,FBL,HNRNPM,NUDC,PRKDC,TUFM,JTB,ILF3,DDX39A,SNRPA,TARS,POLR2A,CBX3,PRDX3,MFAP1,TFDP1,LRPPRC,IMPDH1,KHSRP,NDUFS5,IDH3B,ESPL1,TERF1 |
| 2.251e-34 | -77.48 | RNA processing | biological process | GO:0006396 | 906 | 279 | 17256 | 2622 |
DHX8,USP39,RBM4,PABPC4,RPL23A,UTP25,PA2G4,SNUPN,NOL11,NSRP1,SRSF4,TRA2B,ECD,FTSJ3,PCBP2,SRSF10,CDC5L,NOL8,NSUN2,HNRNPF,WDHD1,DDX20,MAK16,CLNS1A,IWS1,SMAD2,RPS27A,RPS14,LUC7L3,WDR4,RNASEL,RRS1,SMAD1,SMNDC1,DDX42,PRPF38B,LIME1,POLR2K,DHX9,PDCD7,PRPF39,METTL3,CDC73,RAVER2,DDX56,EXOSC7,INTS7,EFTUD2,ZNF326,RTCB,GEMIN4,CPSF4,MRM3,PABPC1,NSUN4,LUC7L2,SRSF11,AGGF1,DHX29,SF3B6,TEX10,TYW1,GTPBP4,RPS10,RPS24,EXOSC9,SRSF5,SF3A2,POLR2J,RBMX,TYW5,ZNF830,KARS,TP53RK,SARNP,IVNS1ABP,SF3B1,C2orf49,PRKACA,APP,RBM23,UTP18,GRSF1,INTS12,AQR,RBM15,ZC3H3,CDK12,MRM2,POLR2L,CRNKL1,RNPS1,POLR2D,RPL38,SLBP,ELP4,GAR1,DHX57,DDX17,PPP2CA,NSA2,DGCR8,LSM6,TBL3,FTSJ1,RPLP1,RBMS1,SNRPG,FUS,PDCD11,CSNK1D,PRPF4B,RPS2,SRSF6,TRMT6,HABP4,JMJD6,RRP36,PNO1,TUT4,GTF2F1,KRI1,RBM17,DNAJC8,RPL17,ELP5,PPP1R8,GEMIN6,RPL19,CNOT6L,GTF2H2,HNRNPM,WDR18,RPL8,TBRG4,BMS1,DDX39A,RPL27A,TSR2,POLR2A,UTP20,RPL32,HNRNPH3,KHSRP,DUSP11,DDX5,WDR62,BYSL,DDX52,DDX47,NOP2,THOC1,PHRF1,RBM8A,YTHDC2,ALKBH5,EBNA1BP2,SNRPD3,KRR1,SF3B2,PAPOLA,EIF4A3,THADA,INTS1,METTL14,TRMU,POP7,KHDC4,GPATCH1,RPF2,CCAR1,SRPK2,METTL1,RPP25,EXOSC6,SNRNP200,SNRPB,SREK1,UTP3,PRKRA,LUC7L,DHX15,GEMIN5,PAF1,RPL37,U2SURP,PQBP1,PRPF4,OSGEPL1,RPS26,GEMIN7,SEPHS2,CTU2,RPS15,ZCCHC8,RPL15,CDK13,THRAP3,SRRT,PRPF18,LYAR,SNRNP25,CMTR2,BUD31,RBM3,YBX1,POLR2I,SUGP2,UTP15,RPL6,RBM38,RPL36,SYNCRIP,RBM25,PRMT7,TRMT10B,SNRNP70,TSEN15,SART1,RPLP2,CHERP,XAB2,LAGE3,RRAGC,PCBP1,RPL11,HNRNPA2B1,ZNF473,DUS4L,EXOSC1,TARDBP,AHCYL1,CHTOP,UTP4,STRAP,PRPF19,CSTF1,RPL29,RPL35,POLR2G,PPIE,METTL2A,SMU1,LSM8,ATXN1,PRPF3,BUD13,TXNL4A,RPS9,RPSA,SRSF1,SUGP1,DUS3L,HNRNPR,DHX16,CWC25,INTS2,CDC40,RRP15,AGO2,GTPBP3,CTNNBL1,CWC27,PPIG,DUS2,FBL,RBM15B,YTHDC1,PPP1R9B,HELB,PSPC1,PPWD1,SYMPK,SNRPA,DDX23,ZC3H7B,ZRANB2,SRSF3,TYW1B |
| 2.630e-34 | -77.32 | nucleoplasm part | cellular component | GO:0044451 | 1113 | 318 | 18223 | 2701 |
ZNF496,MAX,PNISR,ADD1,CXXC1,DHX8,CCNL2,UBE2I,PPP1R16B,RBM4,POLR3K,PARK7,USF1,NEK6,NSRP1,SRSF4,CRY2,TAF5L,SRSF10,CDC5L,ERCC1,EHMT1,ELOA,MKI67,DDX20,TOPORS,SUPT20H,USP22,GINS4,BRMS1,BRD2,RAD18,KIF18B,LIMK1,LUC7L3,TPP2,EIF2D,OGT,FBXL3,HDAC2,SMNDC1,DDX42,POLR2K,PRKAA1,DHX9,EZH1,SUPT7L,METTL3,CDC73,LMNA,TMEM179B,INTS7,HDAC7,EFTUD2,GEMIN4,CPSF4,TNRC18,LUC7L2,TERF2,MORC3,SRSF11,AGGF1,ETV3,ELL2,MTA2,TEX10,BCLAF1,SRSF5,PATL1,SF3A2,FAS,POLR2J,EPOP,MED15,PIAS2,APPL2,ZNF830,CDK2,SGF29,TRIM41,SARNP,TRERF1,SF3B1,RAF1,SUZ12,RMI2,POMP,DAZAP2,PRKACA,SAFB2,TERF2IP,SP100,INTS12,TAP2,FAM76B,RBM15,ZC3H3,CDK12,RPRD1B,RNF169,SAP30,POLR2L,FAM118B,KAT7,CRNKL1,RNPS1,POLR2D,ATP6V0A1,ELP4,EDF1,GAR1,SUPT16H,DDX17,TAF2,KIF2A,DSN1,HINT1,FAAP100,NSMCE2,HIPK2,H2AFX,COIL,ATMIN,PRPF4B,NCOR2,SRSF6,TCF3,BABAM1,HABP4,TKT,CBLL1,WDR5,BLM,GTF2F1,RFWD3,RPA2,PTEN,PPP1R8,PRDM4,GEMIN6,KANSL2,GTF2H2,HNRNPM,MED22,NCOA2,SMC4,ZFP64,KAT2A,POLK,DENND1B,WDR18,DDX39A,POLR2A,RPA1,SH3BP5,TATDN2,PML,DUSP11,TAF6,S100PBP,CCNC,LYRM4,THOC1,UBN1,KMT2E,RBM8A,ALKBH5,CSNK2A1,SIRT2,TAF6L,SNRPD3,RUFY1,MAPK14,MBD4,SF3B2,FANCL,PCNA,GLIS2,EIF4A3,IMPAD1,INTS1,KIF22,RP2,TCEA1,OGG1,CARMIL1,TIMM50,ELOF1,SP3,FYTTD1,LARS,TRIM8,BAZ2A,SREK1,WDR82,EAF2,KMT2C,LSG1,DHX15,GEMIN5,PAF1,EIF4ENIF1,CHD3,TONSL,ATXN2L,PQBP1,CRCP,BAZ1B,ACTB,PRPF4,CHEK2,SINHCAF,GEMIN7,NSMCE4A,ZCCHC8,ZNF768,MED13L,CDK13,THRAP3,PRPF18,RB1,MED8,MED10,MBD2,ZNF335,CTR9,ICE2,AFF1,MAML1,HP1BP3,POLR2I,SUGP2,RTF1,SLTM,APPL1,DAPK3,MBIP,RBM25,TBPL1,RUVBL2,SNRNP70,RBBP4,MBD1,TCF12,USP7,SART1,SUMO2,LAGE3,PCBP1,RPAIN,MEAF6,HNRNPA2B1,OIP5,SAP130,MDM2,ZNF473,BRPF3,PIN1,TARDBP,CHTOP,SAP30L,DVL2,PRPF19,NXT1,POLR2G,PPIE,SMU1,ATXN1,PRPF3,ERBIN,NDUFB1,FANCE,MBD3,TOLLIP,USP36,SRSF1,AFDN,CLK3,ARNTL,CBX4,CWC25,INTS2,CTDP1,TRIP12,EYA1,CDT1,DBF4,SMC6,CSNK1A1,PAGR1,RMI1,KLHL20,PPIG,H2AFY,SS18L1,ORC3,FBL,GINS1,YTHDC1,TELO2,GTF3C6,RPRD1A,PSPC1,TOP3A,POLR3GL,PPWD1,MEN1,API5,HSPA1B,KMT2B,CENPT,ACADM,TAF12,SRSF3,ZMIZ1,TERF1,HIPK3,IFI16 |
| 3.225e-34 | -77.12 | OBSL1 (obscurin like 1) | protein interactions | 23363 | 641 | 228 | 17029 | 2761 |
DDX47,NUP188,HNRNPAB,COPA,NOP2,THOC1,RBM8A,DHX8,CSNK2A1,USP39,EBNA1BP2,SND1,SNRPD3,BRIX1,MAPK14,MYEF2,RBM4,RPL23A,SF3B2,DST,PA2G4,PCNA,NUP210,NOL11,EIF4A3,ATG3,PDS5B,NOC2L,RPF2,TRA2B,KIF22,NUP153,LRRC59,FTSJ3,PCBP2,TIMM50,SRSF10,CDC5L,SNRNP200,EXOSC6,SEPT9,AATF,SNRPB,MKI67,HNRNPF,EZR,PBRM1,MCM2,SLC25A5,DHX15,EIF3A,STOML2,UBTF,AHNAK,BRD2,LUC7L3,U2SURP,PQBP1,BAZ1B,PRPF4,KPNA2,RRS1,AAAS,HDAC2,DDX42,SSRP1,FUBP1,PPIB,EWSR1,CENPF,DHX9,RPL15,TOP2B,THRAP3,XPNPEP3,SRRT,NUP205,LMNA,DDX56,SMC3,MCM5,EFTUD2,RTCB,ZNF326,CAPZA1,YBX1,MCPH1,PABPC1,NUP85,NIPSNAP1,HP1BP3,SRSF11,MTA2,TEX10,ACSL3,SUGP2,RPL6,GTPBP4,EXOSC9,BCLAF1,PLEC,CAPZA2,PKM,ABCF1,SLTM,SF3A2,MATR3,CCT8,XRCC5,PCM1,SYNCRIP,CCDC86,RBM25,RBMX,ACLY,NUP62,YWHAZ,GPI,TCOF1,ATP5F1A,RUVBL2,SNRNP70,RBBP4,HNRNPDL,NUP58,SART1,NDC1,IMMT,CHERP,URB2,XAB2,MDH2,SF3B1,ACTR3,HNRNPUL2,SMARCA4,SAFB2,PCBP1,APP,CHD1,RPL11,HNRNPA2B1,STRBP,KIF14,NUP107,AQR,RBM12B,CHTOP,PDIA6,RBM15,UTP4,PRPF19,CCT2,MAP4K4,SMU1,RNPS1,CRNKL1,NUP155,PRPF3,DNAJA1,GAR1,H2AFV,TRIM28,RPS9,RPSA,SRSF1,SUPT16H,DDX17,AFDN,KIF2A,CHCHD3,ALDH3B1,HNRNPR,DHX16,SAFB,CORO1C,TBL3,TULP3,FUS,PDCD11,COIL,PRPF4B,NIFK,RPS2,TRIP12,RRP15,RAE1,SRSF6,NUP54,CDCA8,FLOT1,NKRF,ATP5F1B,RRP36,RBM17,PSMD2,SEC24C,H2AFY,RPL19,TAGLN2,FBL,PPAN,PSPC1,PRKDC,WDR18,TUFM,LDHA,RPL8,ILF3,POLR3GL,RANGAP1,MACF1,SNRPA,ZFR,POLR2A,PRDX1,CBX3,DDX23,UTP20,PRDX3,MFAP1,HNRNPH3,KBTBD7,KHSRP,DDX5,SRSF3,DDB1,DDX52 |
| 8.924e-34 | -76.10 | mitotic cell cycle process | biological process | GO:1903047 | 619 | 213 | 17256 | 2622 |
POLA2,FGFR1OP,NUP188,MAX,PDCD6IP,GPR132,XIAP,ENSA,CUL1,CNTROB,KIF2C,CCNB1,BECN1,BIRC2,FANCI,MIS12,KIFC1,CDKN2C,RAB8A,PCNA,NUP210,NEK6,RAB35,DNM2,PDS5B,KIF22,NUP153,CDC25B,SEH1L,TACC3,CARM1,PLK1,PLK3,SEPT9,MRNIP,RRM2,CDC6,SMC2,AURKB,BRCA1,ANLN,MCM2,SOX4,OPTN,PRIM1,SEPT1,KIF18B,RPS27A,E2F4,MAP4,ITGB1,CHEK2,VPS4A,RRS1,TFDP2,AAAS,MAPRE1,CLSPN,PPP1R12A,PHF23,RHOC,CENPF,KIF23,TOP2B,HAUS4,RACGAP1,CNOT11,CRLF3,HAUS2,LMNA,NUP205,CNOT3,SPAG5,RTKN,TMEM250,RB1,CCP110,SNX18,MCM5,BANF1,MSH2,FBXL7,KNTC1,MCPH1,NUP85,PRIM2,MYBL2,SEPT8,SEPT7,RHOB,HAUS8,MASTL,PCM1,CDC27,GOLGA2,ODF2,CDCA5,NUP62,CNOT6,NDE1,ZNF830,CDK2,CCNB2,NUP58,CDKN2A,BCCIP,ZNF207,NDC1,CHMP2A,FOXM1,POC1A,DYNLL1,ANK3,TPX2,NUF2,BCL2L1,ORC1,PRKACA,STMN1,CCNA2,MDM2,ABRAXAS2,PPME1,KIF14,AKAP8,NUP107,PPP6C,NABP1,SEPT11,CDKN1B,CEP63,ATF2,CFL1,DCTN1,ANKLE2,PSRC1,BRD4,BIRC3,BTG2,INTS13,TAOK1,CUL3,TUBGCP5,NUSAP1,NUP155,PKMYT1,CDC23,CHMP2B,TAF2,PPP2CA,KIF2A,CHMP4A,DSN1,CEP55,CHMP4B,REEP4,PPP2R2D,CSNK1D,TUBB,CTDP1,KIF3B,MZT1,MCM10,RAE1,MECP2,CDT1,DCTN2,NUP54,DBF4,CDCA8,BLM,SPDL1,NCAPG,RAB11A,TUBGCP2,MAD2L2,SAPCD2,FBXO5,RFWD3,RPA2,CENPJ,PRC1,NABP2,NAA50,GTSE1,ARHGEF2,ORC3,CNOT6L,CAMK2G,SMC4,TGFB1,GINS1,PPP3CA,RHOA,NASP,PRKDC,JTB,BORA,KIF11,RPA1,CNOT9,KIF18A,POLE,BIRC5,TFDP1,E2F1,PML,SSNA1,WDR62,UBE2C,CHMP7,HRAS,ESPL1 |
| 2.196e-33 | -75.20 | MORF_GNB1 | MSigDB lists | MORF_GNB1 | 294 | 130 | 17377 | 2626 |
POLA2,H2AFZ,NUP188,HNRNPAB,ADD1,SND1,PARK7,PABPC4,KIFC1,CALM2,GOT2,TXLNA,HADHB,TRA2B,TCEA1,DNMT1,SRP72,SNRNP200,BAZ2A,MCFD2,MCM2,CBFB,RHEB,PPM1G,ATXN2L,BAZ1B,UQCRH,SMNDC1,HDAC2,RMND5A,MRPL9,MAPRE1,PHB2,RRM1,XPO7,NDUFS4,RPN1,EI24,CAPZA1,TNPO3,IFRD1,WDR1,SUGP2,PSMA1,DCTD,SEPT7,EIF4H,MAP2K2,SF3A2,XRCC5,SDHB,EPRS,CSK,RBMX,PRPS2,MDH1,RUVBL2,RBBP4,CDK2,PTDSS1,TOMM20,IMMT,DYNLL1,COPE,ACTR3,SUMO2,EIF3D,STARD7,STMN1,GNB2,SDHA,RAD23A,HNRNPA2B1,IARS,DUT,PIN1,CS,TARDBP,AHCYL1,PDIA6,PPIF,PPT1,PPIE,RNPS1,PSMB7,VDAC2,DNAJC9,SLBP,NDUFA7,VDAC1,H2AFV,TXNL4A,SERP1,TRIM28,EIF3H,EIF3K,CDC16,DDOST,HNRNPR,SAFB,TIMM17A,NCOR2,TRAK1,LANCL1,AP3S1,DNAJC8,NDUFV1,SEC24C,ANP32A,PTGES3,HNRNPM,NUDC,ELOVL5,MLEC,PRKDC,ILF3,JTB,TUFM,DDX39A,SNRPA,POLR2A,TARS,CBX3,LRPPRC,KHSRP,IMPDH1,NDUFS5,IDH3B,TERF1,ESPL1 |
| 1.307e-32 | -73.41 | GO_MITOTIC_NUCLEAR_DIVISION | MSigDB lists | GO_MITOTIC_NUCLEAR_DIVISION | 339 | 141 | 17377 | 2626 |
SKA3,PDCD6IP,XIAP,ENSA,SIRT2,KIF2C,CCNB1,UBE2I,BECN1,BIRC2,MIS12,KIFC1,NEK6,PDS5B,KIF22,NUP153,CDC25B,MCMBP,SEH1L,PLK1,PBK,NSUN2,KIF15,CDC6,AURKB,SMC2,PBRM1,CCNF,ANLN,KIF18B,ZNF268,CHEK2,VPS4A,RRS1,MAPRE1,PPP1R12A,GORASP1,CENPF,KIF23,RACGAP1,HAUS4,PMF1,HAUS2,SPAG5,RB1,SMC3,SNX18,TIMELESS,FBXL7,KNTC1,MYBL2,SEPT7,HAUS8,MASTL,CDC27,GOLGA2,CDCA5,FAM83D,VCPIP1,NUP62,NDE1,ZNF830,CDK2,CCNB2,ZNF207,CHMP2A,PTTG1,TPX2,SMARCA4,NUF2,OIP5,CCNA2,KIF14,AKAP8,ANAPC7,CEP63,DCTN1,ANKLE2,PSRC1,MAPRE2,BIRC3,TUBGCP5,CUL3,CDCA2,NUSAP1,PKMYT1,CHMP2B,RAB1A,CDC23,TXNL4A,EML4,KIF2A,CHMP4A,CDC16,DSN1,NSMCE2,CEP55,CHMP4B,PPP5C,REEP4,PPP2R2D,ZC3HC1,KIF3B,CTDP1,KLHL21,DCTN2,BABAM1,CDCA8,CDCA3,CDK11B,NCAPG,CSNK1A1,TUBGCP2,RAB11A,MAD2L2,FBXO5,SAC3D1,CCNK,PTEN,NAA50,PRC1,ARHGEF2,NUDC,SMC4,RHOA,ASPM,JTB,ANAPC2,KIF11,BORA,CDK11A,NEK1,KIF18A,BIRC5,CENPT,CHMP7,UBE2C,TERF1,ESPL1,ANAPC4,SSSCA1 |
| 7.485e-32 | -71.67 | cellular protein metabolic process | biological process | GO:0044267 | 3771 | 809 | 17256 | 2622 |
FGFR1OP,KDM4A,MRPS15,MAP3K7CL,PIGQ,HEXB,XIAP,TGOLN2,RBM4,FBXO22,PABPC4,EEF2K,RPL23A,CDK5,PSMD1,NEK6,RAD23B,CRY2,NUP153,FNIP2,RNF26,TIPARP,ANKRD9,MGAT5,SENP1,PCBP2,MRPL57,USP34,PLK3,PGAP2,TMEM115,NRAS,EHMT1,MRPL43,MIER2,TOPORS,DCUN1D5,ICMT,ARF4,STOML2,BRMS1,SMAD2,RAD18,RPS27A,LIMK1,AXIN1,OGT,ATE1,VIPAS39,ST3GAL2,RNASEL,KLHL42,FBXL3,SMAD1,LONP2,AAAS,ZNF720,MRPL9,CLSPN,MRPS2,GGA1,TRIO,KCTD17,TOP2B,EZH1,EIF2AK4,ZNRF3,PSMD9,APH1B,CDC73,MCTS1,ATG4A,DDRGK1,PDXP,EIF2S2,RNFT1,EFTUD2,FBXO7,MRPL21,PABPC1,NUP85,PHKG2,PPA1,UBE2QL1,CARS2,NAGPA,EIF3L,FOXK1,MAPKAPK3,DHX29,MTA2,ERO1A,MAN1B1,RPS10,ARMT1,USP10,MRPL16,EIF4H,ABCF1,PTPRF,FNTA,DUSP3,CSK,SETD3,TEX30,PTAR1,WIPI2,CFAP20,SGF29,RNF139,MRPL3,NUP58,EGLN1,TRIM41,KARS,ABCA3,UBR2,PTTG1,WDTC1,RXYLT1,INO80E,EFL1,PRKACA,STAM,CPNE3,ANKIB1,KTN1,APP,PRKD3,FBXL6,MTA1,DDA1,UBA5,NUP107,NSFL1C,ANAPC7,RNF19A,MAVS,ATF2,RPRD1B,RNF169,ULK3,SEC61B,KAT7,MAP4K4,RPL38,NDUFA7,RAB1A,FKBP3,PPP2CA,PEX5,CDC16,NSMCE2,HIPK2,CAMKMT,RNF38,RPLP1,DMWD,PPP5C,USP13,RPS2,ZFP91,CCM2,TRAK1,JMJD6,UBE4A,WDR5,PPP1R3B,CAPN2,GOLM1,FBXO3,PSMD2,GATC,SUV39H2,HUWE1,PRDM4,NAA50,GTSE1,LTN1,KANSL2,UBE3B,TTLL12,ST8SIA2,GTF2H2,FBXL19,RPL22L1,LYPLA2,SPTAN1,PDPK1,PPP3CA,TNFAIP3,USP42,MRPS10,ZNF862,KEAP1,MAGT1,GPS2,DBI,MAPK6,PML,PARP10,WDR45B,ANAPC4,FAF1,TRIM11,PPP1R15B,CSNK2A1,BIRC2,ZER1,FANCL,TET3,ABL2,RAB8A,PCNA,NUP210,EIF5,ASB6,MRPL32,RYBP,CDC37,PTPRK,PLK1,SP3,PTPN18,RBX1,HARS,BAZ2A,APH1A,SNRPB,TLK1,GMFB,MRPL12,UBE2V1,BRCA1,KRTCAP2,PRKRA,USP21,TRIM4,ALG3,CHD3,SOCS4,QRSL1,ARRDC1,ACTB,NGLY1,NAA60,RMND5A,TMUB1,LAMTOR3,SDC2,ADCK5,CDK13,RAB6A,PPP3CB,B4GALT4,RLF,ASXL2,C1GALT1,NUS1,UBE2Q2,MED8,CCP110,PPIL2,CTR9,MDFIC,MRPL48,MAML1,LRSAM1,DCAF8,LDB1,KRAS,EIF2AK1,MAP4K3,RTF1,UBE4B,NFATC2IP,LY6E,METTL22,EIF4G2,ARMC8,STYXL1,ZDHHC3,NMT2,PSMC4,RPL36,MBIP,GALNT2,CDC27,ZDHHC7,PRMT7,RUVBL2,ECPAS,RNF114,USP7,KCTD7,CYLD,TRAF7,RPLP2,MRPL39,SUMO2,LYN,DUSP22,RAD23A,RPL11,SEC11A,MRPL50,PDK2,PSMA6,MDM2,BRPF3,KMT5C,ABRAXAS2,PIN1,PPME1,MRPL34,MINPP1,LMAN1,SAP30L,CTDSP2,SPSB3,PRPF19,KDM3B,PPIF,RPL29,RPL35,BIRC3,PPT1,PSMA8,RAB7A,BTG2,PPIE,MTMR6,NUP155,KDM1B,MRPS14,EIF3H,RPSA,USP36,MRPL2,DNAJC10,IDE,CLK3,UBXN2B,FASTK,PSMD3,STK38,UHRF2,CHMP4B,NCOA1,H3F3A,LTA4H,AP2S1,USP53,SMAD4,ZC3HC1,CTDP1,KLHL21,AGO2,TMX3,CDCA8,SUMF1,CDK11B,GGA2,CSNK1A1,SCYL2,DNAJB9,PTPN2,HERC3,IRF4,CTSS,CWC27,CAMK2G,RNF5,CNTN5,RPRD1A,RHOA,PRKDC,TUFM,RANGAP1,PPWD1,PCGF1,FBXO41,NEK1,GOLGA7,BIRC5,USP20,SPCS3,TAF12,UBE2C,RPS6KC1,HIPK3,GCSH,TXN,NUP188,PDCD6IP,GXYLT1,ADAM10,PRKCSH,ZDHHC8,CXXC1,CUL1,USP39,NHLRC3,CCNB1,UBE2I,EIF1B,PARK7,ASPHD2,AP2B1,FBXW2,TAF5L,MARCH2,CDC25B,MAST2,SEH1L,AKT2,PBK,GALNT7,AURKB,USP22,CCNF,MCFD2,CBFB,EIF3A,DOT1L,MAP3K4,MKNK1,STT3A,PSMD8,RPS14,TPP2,MRPL27,EIF2D,PTPN7,PTPDC1,ARRB2,ZNF598,CCDC59,HDAC2,B4GALT2,DDX58,WSB2,PPIB,GMFG,DHPS,PRKAA1,GSPT2,B4GALT1,CYCS,MAN2B1,SUPT7L,PSEN1,TMEM165,VPS25,NPLOC4,WDR48,FKBP1A,RPN1,RNF121,KLHL5,ZNRF2,HDAC7,DAD1,PPP4R1,TPST1,DAPK1,PIGG,FBXL7,MRPL40,RNF135,EEF1D,APOL1,MORC3,SOCS5,EIF5A,PIGT,COQ8A,NOA1,MFNG,RPS24,ADRB2,KDM3A,MAP2K2,PSMB3,DERL1,EPRS,GOLGA2,EPOP,QARS,CSNK1G1,PPP3R1,USP32,PIAS2,DCAF11,VCPIP1,YY1,MAP3K5,RNF14,CDK2,NRBP1,ZC3HAV1,NDC1,TP53RK,ATXN3,RWDD1,RAB11B,RPS6KA1,RAF1,SUZ12,EIF3D,RAC1,KLHL18,CRKL,APLP2,CCNA2,SHC1,KDM2A,SIAH1,MTMR4,UCHL5,SOCS6,MRPS27,TTC3,NAA35,ILKAP,CDK12,CFL1,SAP30,TAOK1,CUL3,ELP4,KIAA1586,PKMYT1,ASB13,CDC23,POLG2,PSMB9,ERC1,TRIM28,SERP1,SOCS7,EIF3K,ANKZF1,MRPL55,DDOST,PPP2R5A,JAK1,SEL1L,FTSJ1,PPA2,TRIM32,BEND3,B4GALT3,EYA2,CSNK1D,PRPF4B,OTUD5,B4GALT5,MECP2,MANBA,BABAM1,CDCA3,CBLL1,BRAP,SECISBP2,SDF2L1,RAB11A,POFUT1,WWP2,RFWD3,CCNK,RPL17,PTEN,FUT8,PTPN11,AXIN2,MRPL54,FEM1B,RPL19,COPS7B,MAP3K14,CREB1,OSTC,UBE2M,KAT2A,LONRF3,NEK7,ILF3,PARP4,RPL8,FBXO9,TBRG4,ANAPC2,OTUD3,RHOT1,ARSK,RPL27A,GUF1,MARK2,SPPL2B,FBXO21,NUCB1,HGS,RPL32,PRDX3,TTLL4,PPP1R11,DUSP11,WDR91,CPEB2,DDB1,MIB2,CCNC,ADA2,PIGM,UBE2E2,DCAF15,NF1,KMT2E,MOGS,DNAJC24,PTP4A3,UBE2Z,UBE2Q1,SIRT2,TAF6L,SNRPD3,UBQLN2,USP48,FKBP2,BECN1,MAPK14,MRPL19,RNF103,UBLCP1,PCYOX1L,CDC42,ATG3,JOSD1,SLC35C2,ARID4A,FGFR1OP2,CARM1,TIMM50,SRPK2,COPS8,LARS,TRIM8,DPM1,NCK1,VHL,RIOX2,WDR82,SUMF2,KMT2C,STK17B,RPL37,MAN2A2,GEMIN5,PAF1,UEVLD,PPM1G,IARS2,CAB39,BAZ1B,STK11,CHEK2,VPS4A,GALNT10,ROCK1,COPS6,MRPL13,RPS26,PSMC1,DCAF5,UBE2D3,RPS15,PIGN,PPP1R12A,GORASP1,UFC1,UBXN1,RPL15,MEF2A,TTF1,RHBDD1,NUP205,DTL,MED10,PYURF,ZNF335,BCL2,YBX1,ZRANB1,UBE3C,CSNK1G3,ERLIN1,RPL6,PSMA1,SYVN1,EIF2A,VKORC1,DAPK3,ISG15,CAND1,MASTL,KLHL15,SIAH2,FN3KRP,NUP62,CTSA,NAA20,RBBP4,PRKAB1,TOMM20,ASH1L,MPHOSPH8,WDYHV1,MDH2,NSD3,EXT2,PAIP1,MEAF6,USP5,FARSA,UBXN2A,BABAM2,IARS,KIF14,PPP6C,RPN2,PDIA6,ABI1,SCYL3,HTRA2,RLIM,PGGT1B,RNF25,PCGF6,PSMB7,OGDH,EDEM2,MBD3,TOLLIP,EIF3G,RPS9,BTBD1,DAP3,TAB2,CHCHD1,ARNTL,FKBP5,USP11,SMURF1,MAPK1,PPP2R2D,ABCA1,CBX4,PDF,SH2D3A,TRIP12,MRPL42,SHPRH,RAE1,EYA1,SCYL1,NUP54,MRPS26,DCUN1D4,GFM2,MAN1A1,SPPL2A,FASTKD3,FGFR3,GRK2,KLHL20,KMT5A,PPIG,PELO,RRBP1,MRPL11,FBL,SLC35A1,TGFB1,B3GALT6,ZDHHC18,CSNK1G2,DCAF6,ADAM17,HEMK1,MIER1,PRKAR1B,RFFL,RCOR1,WDR81,PRMT2,MEN1,CDK11A,TARS,MAPK3,MTMR3,CTSL,PLAA,DTX4,KBTBD7,KMT2B,MBD6,PLOD3,HRAS |
| 8.673e-32 | -71.52 | GO_ESTABLISHMENT_OF_LOCALIZATION_IN_CELL | MSigDB lists | GO_ESTABLISHMENT_OF_LOCALIZATION_IN_CELL | 1570 | 407 | 17377 | 2626 |
CCDC93,RAB14,TMED7,PDCD6IP,NUP188,TSC2,TAP1,AP3M2,TGOLN2,CCNB1,SYNRG,PARK7,SLC25A37,FBXO22,RPL23A,KIFC1,CDK5,NAPG,SNUPN,NSRP1,RABGAP1L,SRSF4,RAB4A,AP1M1,DNM2,AP2B1,NUP153,TFG,SEH1L,SRSF10,SRP72,BAK1,USO1,RHOBTB3,TMEM115,AKT2,KIF15,DDX20,PPFIA3,NUTF2,MCFD2,ICMT,SLC25A5,RAB22A,RAB2B,ARF4,STOML2,HHEX,WAS,TMED10,RPS27A,RPS14,EIF2D,MAP4,MYO18A,ITGB1,RRS1,NMD3,LONP2,AAAS,SLC25A33,DNAJC5,SEC61G,GGA1,RAB23,KIF23,TMED3,PSEN1,TMEM165,VPS25,COPG2,COPB2,LMNA,NPLOC4,SPAG5,ATG4A,CD59,SNX18,FBXO7,TNPO3,GEMIN4,PIKFYVE,SYTL3,PPP6R1,NUP85,TMED2,NAGPA,SRSF11,EIF5A,TIMM8B,GCC2,RPS10,SSR2,RPS24,MTX1,RIT1,SRSF5,ADRB2,TOMM40,PTTG1IP,GOSR1,RHOB,SEC31A,DERL1,SCARB2,KPNA1,GOLGA2,NSF,FAM83D,PPP3R1,PPP6R3,NDE1,NRBP1,ALS2,RHOG,ANKRD27,SARNP,SYS1,RAB11B,RAF1,ACTR3,ANK3,VTI1A,MYH9,TBC1D13,BCL2L1,AP1B1,STAM,APP,MOAP1,RAB21,ATP2A2,RALB,TBC1D22A,TBC1D14,NUP107,TNPO2,TAP2,TP53BP2,ATF2,GCC1,ZC3H3,DCTN1,SNX8,PSRC1,SEC61B,GOPC,RPL38,CUL3,RNPS1,POLR2D,SLBP,HTATIP2,NUSAP1,CDC23,RAB1A,AP4E1,ERC1,KIF2A,HSPA4,PEX5,CHMP4A,SEC61A1,RAB24,VPS26B,RPLP1,SEL1L,SNRPG,EYA2,DYNC1LI2,CSNK1D,TUBB,RPS2,SCAMP3,SRSF6,TRAK1,SLC25A12,IFT27,RAB11A,PIP5K1C,PDCD10,RPL17,ARF5,GEMIN6,RPL19,UPF2,MTX2,IFT46,TPCN1,PACS2,SPTAN1,PPP3CA,DENND1B,MRS2,RPL8,HEBP2,PACS1,RAB3IP,RHOT1,ZP3,RPL27A,DDX39A,KIF11,MACF1,PICALM,HGS,KIF18A,RPL32,STX18,TFDP1,LRPPRC,PML,SSNA1,YWHAH,ESPL1,VPS29,IPO4,SNAPIN,POLA2,MTX3,COPA,THOC1,NF1,RBM8A,SNX15,ALKBH5,AGFG1,KIF2C,SNRPD3,SEC16A,BECN1,SSR1,RAB8A,RAP1A,NUP210,CDC42,EIF4A3,TIMM23,DPYSL2,ATG3,AP3S2,SIVA1,RAB35,NOC2L,KIF22,RP2,TIMM50,CDC37,FYTTD1,SNRPB,TLK1,EZR,STX16,RAB5B,LSG1,OPTN,GEMIN5,RPL37,TRAM2,TBC1D17,TIMM13,KPNA2,DVL1,VPS4A,CLN3,RPS26,GEMIN7,TBC1D12,RPS15,GORASP1,PHB2,CENPF,NKD2,RPL15,KLC1,RACGAP1,RAB6A,XPO7,RHBDD1,NUP205,KIF13B,BANF1,ARL6IP1,BCL2,KIFAP3,GLE1,KDELR1,PREB,TRAPPC9,NUDT4,RPL6,KRAS,SYVN1,ZDHHC3,BBS12,NMT2,RPL36,GNAS,TSC1,GOLGA4,PCM1,SNAP23,CDCA5,SIL1,NUP62,CTSA,YWHAZ,EHD4,TOB1,SNX27,CHMP2A,CORO7,TOMM20,RPLP2,CHERP,DYNLL1,COPE,LYN,BCAP31,RPAIN,RPL11,ANKRD28,HNRNPA2B1,SAR1A,KIF14,PPP6C,BCAP29,CORO1A,CLTB,CHTOP,LMAN1,AHCYL1,F2R,PPIF,RPL29,NXT1,RPL35,PPT1,RAB7A,ATXN1,NUP155,BICD2,CHMP2B,VDAC1,BUD13,RPS9,RPSA,TMEM201,SRSF1,SURF4,TIMM17A,ARNTL,CEP55,AP1S1,CHMP4B,FAU,MAPK1,SMURF1,AP2S1,ABCA1,PARD3,KIF3B,CDC40,GOLPH3L,RAE1,EYA1,SCYL1,DCTN2,VPS45,NUP54,CDCA8,CHIC2,ARF1,GGA2,AP3S1,SCYL2,KIF5B,STARD9,KLHL20,SEC24C,ARHGEF2,ANP32A,ABCD1,STAT3,MYO5A,RBM15B,TGFB1,SNX2,ATP2C1,COG1,WDR81,RHOT2,MAPK3,MFN2,RAB18,KPNA4,UPF1,PDCD6,SEC23IP,GOLGA7,BIRC5,SNAP29,E2F1,PKD2,SRSF3,CHMP7,TERF1 |
| 3.576e-31 | -70.11 | SNW1 (SNW domain containing 1) | protein interactions | 22938 | 537 | 196 | 17029 | 2761 |
PDCD6IP,HNRNPAB,COPA,YTHDC2,DHX8,CUL1,UBE2Q1,EBNA1BP2,KIF2C,SND1,SNRPD3,USP48,CCNB1,RBM4,FANCI,SF3B2,PSMD1,SNUPN,EIF4A3,INTS1,DNM2,NUP153,SEH1L,CDC5L,SRP72,PLK1,FYTTD1,SNRNP200,SEPT9,HARS,HNRNPF,AURKB,ANLN,RFC2,LUC7L,DHX15,AHNAK,SMAD2,RAD18,CHD3,LUC7L3,U2SURP,BCL7C,PRPF4,KPNA2,ACTB,COPS6,PSMC1,ZMAT3,PFKP,HDAC2,DDX42,FUBP1,VAV2,DHX9,RACGAP1,METTL3,COPG2,CDC73,LMNA,RB1,VASP,SMC3,EFTUD2,BUD31,RTCB,ZNF326,CAPZA1,MSH2,GEMIN4,CPSF4,MVP,PABPC1,LUC7L2,SRSF11,SF3B6,GTPBP4,KRAS,ARID1A,PLEC,SRSF5,SEPT7,MAP2K2,CCT8,PSMC4,CAND1,MAGED2,KPNA1,SYNCRIP,GOLGA2,CDC27,NSF,CSK,RBMX,EXOC4,ARAP1,YJU2,RUVBL2,SNRNP70,EHD4,ZNF830,EXOC3,SART1,CHERP,XAB2,SF3B1,SUZ12,CHD1L,OLA1,MYH9,NUF2,AP1B1,PCBP1,CPNE3,HNRNPA2B1,UCHL5,UBA5,TARDBP,AQR,RBM15,CDK12,DCTN1,PRPF19,CCT2,CDKN2AIP,SHOC2,RFC3,INTS13,PPIE,TAOK1,CUL3,CRNKL1,NUP155,DNAJA1,CDC23,SRSF1,HNRNPR,RBL1,PSMD3,CEP55,FUS,NCOA1,SNRPG,NKAPD1,SMAD4,DYNC1LI2,TUBB,NCOR2,CDC40,TRIP12,RAE1,SRSF6,DCTN2,BABAM1,TRMT6,BLM,WDR5,NCAPG,TUBGCP2,SCYL2,RBM17,PSMD2,CTNNBL1,CWC27,ARHGEF1,ARHGEF2,ORC3,UBE2M,NCOA2,MSH6,HNRNPM,SMC4,NUDC,SPTAN1,BTAF1,PRKDC,WDR18,ABCF2,RANGAP1,MEN1,DDX39A,KIF11,API5,SYMPK,PICALM,RPA1,DDX23,UPF1,POLE,MFAP1,MAPK6,DDX5,SRSF3,RBPJ,PURA,DDB1 |
| 3.897e-31 | -70.02 | RODRIGUES_THYROID_CARCINOMA_POORLY_DIFFERENTIATED_UP | MSigDB lists | RODRIGUES_THYROID_CARCINOMA_POORLY_DIFFERENTIATED_UP | 585 | 199 | 17377 | 2626 |
H2AFZ,YTHDF3,AGFG1,KIF2C,LACTB2,IKBIP,CCNB1,BRIX1,FANCI,FBXO22,SSR1,PAPOLA,LIN9,PCNA,IL6ST,PHTF1,MOB1A,MYBL1,MCMBP,DNMT1,SEH1L,SRSF10,SRPK2,WDR41,COPS8,SGCE,RHOBTB3,NRAS,RAD51AP1,PBK,TLK1,MKI67,GMFB,PSMG1,WDHD1,CDC6,BRCA1,SMC2,ANLN,MCM2,CBFB,RFC2,BRWD1,RAD18,PSMD8,ZNF367,WDR4,U2SURP,ITGB1,SOCS4,ADAM9,KPNA2,TFDP2,SASS6,MRPL13,NMD3,C16orf87,PRKAA1,CENPF,DHX9,RRM1,RACGAP1,CYCS,ASXL2,DTL,LYAR,SUB1,SMC3,EIF2S2,INTS7,ATIC,PHF14,KNTC1,CSNK1G3,EIF5A,AGGF1,ERLIN1,LDB1,GTPBP4,UTP15,EXOSC9,LY6E,FXR1,EIF4G2,CCT8,MATR3,PI4K2A,MASTL,DERL1,EPRS,MTHFD2,CEBPG,SLC16A1,CTSA,YWHAZ,RBBP4,NDE1,TSEN15,EGLN1,BCCIP,ATXN3,CKLF,NQO1,SLC2A1,UCK2,TMEM97,GLRX3,STMN1,STAM,TMEM161B,CCNA2,SAR1A,UCHL5,KIF14,RNASEH2A,SLC39A9,PSRC1,MKLN1,CDC123,DNAJC9,NLN,NUSAP1,NUP155,SHCBP1,ARL5B,SUPT16H,CHCHD3,KIF2A,DNAJC10,RAD51C,IDE,HSPA4,DSN1,CCDC14,RBL1,TIMM17A,SEL1L,MAPK1,XRCC4,AP2S1,ZNF146,DNAJC2,MRPL42,SRSF6,DBF4,SMC6,SIKE1,CHAC2,DCUN1D4,CSNK1A1,NCAPG,GFM2,PIP4K2A,MAD2L2,TFRC,FBXO5,RFWD3,KIF5B,GART,CLIC4,SUV39H2,TANK,PRC1,GTSE1,SGCB,GTF2H2,UBE2M,MSH6,SMC4,GINS1,RPAP3,RPRD1A,NASP,GALC,PRKDC,ABCF2,CCDC34,ADSL,BMS1,DDX39A,GUF1,TARS,CBX3,KPNA4,KIF18A,ATAD2,GOLGA7,PFDN4,LRPPRC,C4orf46,IMPDH1,HMGB2,WDR76,SPCS3,PLOD3,ATP6V1C1,UBE2C,FAF1,IFI16 |
| 5.584e-31 | -69.66 | CAND1 (cullin associated and neddylation dissociated 1) | protein interactions | 55832 | 678 | 230 | 17029 | 2761 |
ZNF76,DDX47,HNRNPAB,NOP2,MRPS15,YTHDC2,DHX8,CUL1,USP39,EBNA1BP2,SND1,SNRPD3,CCNB1,BRIX1,SEC16A,RBM4,MRPL19,PABPC4,SSR1,RPL23A,SF3B2,KRR1,CMSS1,EIF4A3,SRSF4,TRA2B,CRY2,TECR,TFG,LRRC59,SMARCE1,FTSJ3,CCAR1,CARM1,SRSF10,SRPK2,CDC5L,SRP72,SNRNP200,AATF,RBX1,SNRPB,NSUN2,MRPL12,MRPL43,MKI67,HNRNPF,BRCA1,DCUN1D5,PRKRA,MCM2,SLC25A5,RFC2,DHX15,TIMM13,LUC7L3,RPS14,PPM1G,U2SURP,PRPF4,KPNA2,ACTB,FBXL3,CLN3,SSRP1,RPS15,MRPL9,EWSR1,MRPS2,DHX9,TIA1,RPL15,CTCF,THRAP3,PRPF39,ARID1B,CDC73,CNOT3,LYAR,DDX56,EIF2S2,CCP110,ZNF746,ZNF326,RTCB,CTPS1,YBX1,RBM3,AHCY,ANKHD1,MRM3,PABPC1,LUC7L2,HP1BP3,SRSF11,RBM42,PRRC2A,SF3B6,RPS10,RPL6,GTPBP4,RPS24,EXOSC9,BCLAF1,SRSF5,FXR1,MATR3,PHF6,RPL36,CAND1,DERL1,SDHB,NAP1L1,OSBPL11,KPNA1,SYNCRIP,RBMX,ACLY,USP32,TCOF1,ATP5F1A,SNRNP70,CDK2,HNRNPDL,MRPL3,ZC3HAV1,KARS,RPLP2,MRPL39,SF3B1,EIF3D,HNRNPUL2,LAGE3,SMARCA4,SAFB2,PCBP1,SDHA,PAIP1,RPL11,HNRNPA2B1,ZNF302,STRBP,GRSF1,DDA1,AKAP8,MRPS27,TARDBP,PDIA6,PRPF19,RPL35,RPL38,CIRBP,RNPS1,CUL3,DNAJC9,GAR1,H2AFV,TRIM28,RPS9,RPSA,DHX57,SRSF1,SUPT16H,DDX17,DNAJC10,HSPA4,HNRNPR,STAT1,RPLP1,FUS,SNRPG,PDXK,SCARB1,FAU,USP11,PDCD11,TUBB,UNK,NIFK,RPS2,SRSF6,AGO2,TRMT6,MRPS26,JMJD6,PAWR,NKRF,ATP5F1B,WDR5,DCUN1D4,BLM,SLC25A43,TUT4,PNO1,RPL17,SEC24C,DDX31,RPL19,POLR1B,NAP1L4,MRPL11,RPL22L1,UBE2M,HNRNPM,PPAN,STAU1,DDX24,LDHA,RPL8,ILF3,RPL27A,ZNF407,SNRPA,ZFR,POLR2A,PRDX1,HSPA1B,UPF1,PDCD6,TRIM26,RPL32,HNRNPH3,KHSRP,DDX5,ACADM,SRSF3,PLOD3,PURA,DDB1,DDX52 |
| 1.069e-30 | -69.01 | MORF_RAN | MSigDB lists | MORF_RAN | 251 | 114 | 17377 | 2626 |
KARS,H2AFZ,HNRNPAB,RPLP2,DYNLL1,RAC1,SUMO2,COPE,STARD7,UBE2I,SDHA,PARK7,BCAP31,RPL11,RAD23A,RPL23A,HNRNPA2B1,PCNA,UTP18,CS,HADHB,RPN2,TARDBP,TCEA1,PCBP2,CCT2,SNRNP200,SEC61B,CDC123,SNRPB,PSMB7,RNPS1,VDAC2,TMEM147,H2AFV,SLC25A5,TRIM28,RHEB,CLNS1A,EIF3H,STOML2,EIF3K,DAP3,HSPB11,HINT1,RPS27A,PSMD8,PPM1G,COX5A,UQCRH,BTF3,SNRPG,COPS6,FAU,PSMC1,AP2S1,MYL12B,MIF,COX5B,MRPL9,PHB2,PDAP1,NACA,DCTN2,COX4I1,CYCS,MYL6B,EBP,ERH,NDUFV1,DNAJC8,NDUFA2,HUWE1,BANF1,CAPZA1,YBX1,CYC1,FBL,PABPC1,EEF1D,TMED2,NIPSNAP1,HMGN1,POLR2I,JTB,RPS10,TUFM,LDHA,RPL6,SSR2,RPS24,EIF4G2,DDX39A,EIF4H,COMMD4,SNRPA,PRDX1,PSMB3,CBX3,GNAS,NAP1L1,PDCD6,RBMX,COX7A2L,COX8A,ACLY,MDH1,YWHAZ,SRSF3,RUVBL2,GPI,NDUFS5,IDH3B,PGAM1 |
| 1.141e-30 | -68.95 | DANG_BOUND_BY_MYC | MSigDB lists | DANG_BOUND_BY_MYC | 1048 | 299 | 17377 | 2626 |
TXN,H2AFZ,TSC2,NDUFB6,PRKCSH,TSC22D3,CXXC1,XIAP,CCNB1,RBM4,POLR3K,PA2G4,UPRT,NUP153,CDC25B,ZNRD1,USO1,NRAS,GABPA,KIF15,MCL1,RFC2,ARF4,CLNS1A,MKNK1,TMED10,RPS27A,PSMD8,TPP2,PRDX5,WDR4,ITGB1,ARRB2,OAZ1,PTOV1,DDX58,RECQL,MAPRE1,SCOC,CUTA,SLC4A2,LMNA,SPAG5,GNS,SLC31A1,RNFT1,MCM5,MSH2,MRPL40,PPA1,NAGPA,SRSF11,SIGMAR1,MYBL2,MFNG,SRSF5,FXR1,ELK1,EIF4H,CCT8,HMGN2,AKAP1,DCK,MDH1,YY1,MAP3K5,RHOG,CYTIP,IVNS1ABP,CHD1L,ACTR3,UROD,OLA1,CREBL2,STMN1,APP,EPM2A,PAIP2,ADCY9,CLCN6,CDKN1B,AQR,SAP30,SEC61B,MAPRE2,MKLN1,ERF,VDAC2,E2F3,RNPS1,SLBP,KIAA1586,RAB1A,AP4E1,SERP1,MAT2A,SUPT16H,DDX17,PPP2CA,EIF3K,CDC16,HSPA4,HINT1,CORO1C,FTSJ1,H2AFX,CBWD1,ATF6,NDUFS1,SCAMP3,TRMT6,SDF2L1,LANCL1,WDR5,BLM,PMVK,RAB11A,HMG20A,PNO1,MAT2B,PDCD10,NDUFA2,NDUFB4,CRAT,RPL19,TAGLN2,CREB1,GTF2H2,IMPA2,PDPK1,PPP3CA,TK1,GALC,LDHA,RPL8,RPL27A,TTC33,CBX3,YIF1A,SLC19A1,GNA12,KEAP1,RPL32,PRDX3,CCDC6,MFAP1,PARG,ACOX1,DBI,KHSRP,DDX5,PSAP,YWHAH,IGBP1,VPS29,DDB1,DEF6,CCNC,UBL3,SRM,COX15,IER2,GPR132,PLXNC1,NOP2,UQCR10,RBM8A,ABCB10,FKBP2,SNRPD3,MBD4,RAB8A,PCNA,PPP1R12C,HADHB,SRI,TTC4,MTPN,ARID4A,METTL1,DPM1,HARS,SNRPB,RAD51AP1,VHL,PSMG1,CDC6,PRKRA,ODC1,PRPSAP1,STX16,RHEB,DPYSL3,RPL37,MAN2A2,U2SURP,PQBP1,BAZ1B,CLN3,RPS26,UBE2D3,RPS15,LZTR1,PPP1R12A,PHB2,UBXN1,NACA,CIB1,ASAH1,RPL15,THRAP3,RGS2,RAPGEF6,MLX,VASP,CAPZA1,RBM3,ACAD8,SLC12A2,ALDH9A1,DCAF8,ERLIN1,AMD1,PSMA1,STYXL1,APPL1,ZNF174,RXRB,PSMC4,NAP1L1,PCM1,NFIL3,COX7A2L,PRPS2,NUP62,RBBP4,PTDSS1,TCF12,MBD1,BCCIP,PRKAB1,GLT8D1,SUCLG1,CHERP,FOXM1,LAGE3,IRF3,HNRNPA2B1,CSDE1,PDK2,MDM2,PPP6C,AHCYL1,CLCN3,NXT1,BIRC3,PPIE,PSMB7,NUP155,BTBD1,SRSF1,DAP3,RBL1,PSMD3,TULP3,STAT6,USP11,LTA4H,ZNF146,BCL2L12,CMAS,NUP54,ARFIP2,ARF1,NCAPG,TFRC,FBXO5,IRF4,SLC1A4,CWC27,H2AFY,PTGES3,POLR1B,RBM15B,GINS1,AMPD2,TGFB1,PRKDC,MEN1,SYMPK,SNRPA,SERF1B,CACNB1,ATP6V1D,E2F1,ACADM,IDH3B,PLOD3,UBE2C |
| 1.176e-30 | -68.92 | GOBERT_OLIGODENDROCYTE_DIFFERENTIATION_UP | MSigDB lists | GOBERT_OLIGODENDROCYTE_DIFFERENTIATION_UP | 521 | 183 | 17377 | 2626 |
SRM,POLA2,SKA3,H2AFZ,TMEM109,KIF2C,CCNB1,FANCI,LIN9,CDKN2C,PA2G4,NUP210,SIVA1,DNAAF2,XRCC2,NOC2L,KIF22,CDC25B,RNF26,MCMBP,MYBL1,ZNRD1,DNMT1,TACC3,PLK1,PBXIP1,PBK,RAD51AP1,MKI67,RRM2,DDX20,WDHD1,CKAP2L,CDC6,AURKB,SMC2,CCNF,MCM2,RFC2,ODC1,STK17B,ASF1B,PRIM1,GEMIN5,CDCA4,KIF18B,RAD18,TONSL,LIMK1,ZNF367,KPNA2,ROCK1,CHEK2,SASS6,E2F2,AAAS,PTOV1,CLSPN,HJURP,CHTF18,CENPF,NKD2,RRM1,KIF23,RACGAP1,HAUS4,PMF1,SPAG5,LYAR,DTL,C12orf10,MCM5,TIMELESS,KNTC1,NUP85,PABPC1,VOPP1,PRIM2,MYBL2,DCTD,MATR3,HAUS8,PALB2,PDLIM1,CDCA5,LPCAT4,FAM83D,TCOF1,RBBP4,CDK2,CCNB2,CDKN2A,FAM72A,FOXM1,DYNLL1,PTTG1,TPX2,PMS2,TMEM97,NUF2,ORC1,STMN1,TCF19,OIP5,ANKLE1,CCNA2,UCHL5,DUT,LPIN2,NUP107,PPIF,SNX25,RFC3,PSRC1,SLBP,DNAJC9,CDCA2,NUSAP1,PKMYT1,SHCBP1,JAK1,RBL1,CEP55,H2AFX,ANP32E,BEND3,ADAM23,MCM10,DEPDC1,C1orf112,CDT1,DBF4,CDCA3,CDCA8,NUP54,PAWR,BLM,NCAPG,FBXO5,SPPL2A,RPA2,CCNK,FGFR3,SUV39H2,PRC1,GTSE1,GEMIN6,CENPM,MSH6,IMPA2,SMC4,LDHB,GINS1,TK1,MLEC,NASP,HMGN5,ASPM,NET1,CCDC34,RANGAP1,BORA,KIF11,POLR2A,RPA1,KIF18A,ATAD2,POLE,TTLL4,BIRC5,FAM110A,CDCA7L,E2F1,AEN,C4orf46,HMGB2,CENPT,WDR76,WDR62,UBE2C,ESPL1,TERF1,GPATCH4 |
| 2.928e-30 | -68.00 | NUYTTEN_EZH2_TARGETS_DN | MSigDB lists | NUYTTEN_EZH2_TARGETS_DN | 929 | 273 | 17377 | 2626 |
FGFR1OP,ADD1,TGOLN2,GYG1,CCNB1,UBE2I,KIFC1,CDK5,CNPY4,AP2B1,MARCH2,SLC26A2,PBK,KIF15,WDHD1,AURKB,NUTF2,DIDO1,MCM2,GINS4,PRIM1,RAD18,RBM47,KIF18B,WDR4,ITGB1,MLYCD,E2F2,HDAC2,SSRP1,WSB2,NDUFV2,CLSPN,CHTF18,CERK,KIF23,HAUS4,PMF1,SPAG5,SMC3,ZNF326,GEMIN4,RPS10,GTPBP4,BCLAF1,C9orf40,DTWD1,SERTAD2,DCK,FAM83D,TCOF1,WIPI2,NDE1,POC1A,PTTG1,RAC1,TPX2,RMI2,TMEM97,MYH9,CREBL2,NUF2,SLC35B2,DAZAP2,TCF19,CD320,ARL6IP6,CYHR1,CCNA2,SP100,MTMR4,UTP18,ADCY9,RNASEH2A,CGGBP1,CCT2,PSRC1,MAP4K4,CUL3,ABHD11,GALK2,SHCBP1,H2AFV,AMZ2,RAD51C,PPP2R5A,DSN1,ACYP1,CCDC14,CERS6,NSMCE2,H2AFX,BEND3,GEN1,LRP8,ATMIN,DEPDC1,C1orf112,CCM2,FLOT1,CDCA3,WDR5,BLM,SLC25A43,IFT27,FAM8A1,RFWD3,CCNK,DNAJC8,ADD3,CENPJ,PRC1,GEMIN6,GTSE1,IMPA2,HNRNPM,SMC4,JMJD4,MRS2,DDX39A,COMMD4,FBXO21,C1orf131,PITX1,TFDP1,HMGB2,WDR76,YWHAH,THAP5,GPATCH4,PIGM,SKA3,RBM8A,ALKBH5,KIF2C,SLC29A1,GIT2,ATPAF1,FANCI,PCYOX1L,PAPOLA,LIN9,NUP210,CDC42,THADA,IMPAD1,SLC44A1,KIF22,NFU1,MCMBP,MYBL1,TACC3,DRAM2,ABCC5,SP3,PLK1,PTPN18,CCDC138,PBXIP1,SNRPB,RAD51AP1,TLK1,RRM2,CKAP2L,PSMG1,BRCA1,PRPSAP1,CHAF1A,TRIM4,TONSL,BAZ1B,OSGEPL1,SASS6,POT1,ZCCHC9,HJURP,CENPF,RPL15,RACGAP1,PPP3CB,LYRM2,DTL,UBE2Q2,BANF1,TIMELESS,MDFIC,KNTC1,ALDH18A1,SLC12A2,HP1BP3,NIPSNAP1,PREB,GBA,EIF2AK1,IRF5,RBM38,HAUS8,TSC1,ORMDL2,SNAP23,ODF2,CDCA5,PRPS2,NAA20,BTBD10,CCNB2,PDSS2,TIGD2,GLT8D1,FOXM1,LAGE3,TWF2,RPAIN,MEAF6,MRPL50,OIP5,KIF14,EFCAB11,RPAP1,TOP1MT,F2R,MND1,NXT1,POLR2G,MTMR6,NUP155,FANCE,USP36,RAD54B,TMEM41A,CEP55,FKBP5,SPRYD4,REEP4,PDCD2L,BCL2L12,CMAS,GOLIM4,MCM10,MIF4GD,MRPL42,CASP6,CDK2AP2,CDT1,TMX3,CDCA8,ARFIP2,GGA2,RMI1,FZD6,TFRC,SAC3D1,GTPBP3,GART,ZDHHC13,ANP32A,TMEM99,CENPM,MRPL11,FBL,NIPAL3,NASP,HMGN5,ASPM,ATP2C1,METTL5,BORA,ATAD2,BIRC5,NEIL3,IMPDH1,ATP6V1C1,UBE2C |
| 3.248e-30 | -67.90 | MORF_XRCC5 | MSigDB lists | MORF_XRCC5 | 222 | 105 | 17377 | 2626 |
POLA2,IMMT,TOMM20,H2AFZ,NUP188,HNRNPAB,ADD1,DYNLL1,EIF3D,SUMO2,STARD7,UBE2I,STMN1,PARK7,PABPC4,RAD23A,HNRNPA2B1,IARS,PIN1,DUT,TXLNA,CS,HADHB,TRA2B,TARDBP,TCEA1,PDIA6,DNMT1,CCT2,SNRNP200,AATF,PPIE,VDAC2,PSMB7,RNPS1,SLBP,DNAJC9,NDUFA7,MCFD2,MCM2,TXNL4A,CBFB,H2AFV,EIF3H,CHAF1A,SRSF1,NSA2,DAP3,CDC16,HNRNPR,TIMM17A,SAFB,PPM1G,BAZ1B,UQCRH,HDAC2,SSRP1,COX5B,MAPRE1,PHB2,RRM1,DHX9,XPO7,HDDC2,NDUFS4,RPN1,NDUFV1,DNAJC8,AHSA1,CAPZA1,ANP32A,NAP1L4,PTGES3,HNRNPM,NUDC,IFRD1,MLEC,PRKDC,WDR1,WDR18,JTB,TUFM,PSMA1,DCTD,SEPT7,DDX39A,API5,SNRPA,POLR2A,XRCC5,SDHB,EPRS,CSK,PRPS2,ACLY,LRPPRC,IMPDH1,MDH1,RUVBL2,NDUFS5,SNRNP70,IDH3B,CDK2,PTDSS1,TERF1 |
| 3.318e-30 | -67.88 | MORF_DEK | MSigDB lists | MORF_DEK | 250 | 113 | 17377 | 2626 |
KARS,H2AFZ,NUP188,HNRNPAB,CHERP,RAF1,SUMO2,STARD7,CUL1,UBE2I,SDHA,PARK7,RAD23A,TERF2IP,CRKL,HNRNPA2B1,PCNA,DUT,PIN1,CS,HADHB,TRA2B,TARDBP,TCEA1,PCBP2,SP3,KDM3B,CCT2,SNRNP200,SEC61B,AATF,CDC123,SNRPB,PSMB7,RNPS1,VDAC2,AURKB,MCM2,H2AFV,SLC25A5,SERP1,TRIM28,RHEB,EIF3H,CLNS1A,SRSF1,STOML2,KRIT1,NSA2,EIF3K,PPP2CA,KIF2A,DAP3,HSPB11,ACYP1,HNRNPR,RPS27A,SAFB,PPM1G,UQCRH,COPS6,HDAC2,SMNDC1,MRPL9,SEC61G,PHB2,NACA,CTCF,COX4I1,XPO7,AP3S1,EBP,ERH,NDUFV1,DNAJC8,HUWE1,ARPC5,BANF1,CAPZA1,MSH2,NAP1L4,CYC1,FBL,HNRNPM,MSH6,IFRD1,HMGN1,POLR2I,ILF3,JTB,TUFM,LDHA,RPL6,SEPT7,DDX39A,EIF4H,SNRPA,POLR2A,RPA1,XRCC5,CBX3,NAP1L1,SYNCRIP,RBMX,COX7A2L,ACLY,LRPPRC,HMGB2,MDH1,YWHAZ,SRSF3,IDH3B,CDK2 |
| 5.499e-30 | -67.37 | chromosome | cellular component | GO:0005694 | 1021 | 288 | 18223 | 2701 |
MAX,H2AFZ,CCNB1,UBE2I,PARK7,MIS12,USF1,PARPBP,PDS5B,SMARCE1,DNMT1,SEH1L,CDC5L,ERCC1,GABPA,EHMT1,MKI67,WDHD1,SMC2,AURKB,MCM2,RFC2,GINS4,PRIM1,DOT1L,BRMS1,SMAD2,RAD18,RRS1,SLF1,HDAC2,SSRP1,RECQL,CHTF18,DHX9,TOP2B,PMF1,PSEN1,CDC73,YY1AP1,SPAG5,SMC3,INTS7,MCM5,MSH2,TNRC18,NUP85,TERF2,PHF10,ETV3,PRIM2,ZMYND11,MTA2,MYBL2,EXOSC9,ARID1A,KDM3A,PHF6,HMGN2,XRCC5,EPOP,SETD3,RBMX,APPL2,NDE1,YY1,ZNF830,CDK2,CDKN2A,ZNF207,DNMT3A,UBR2,SUZ12,MAGED1,NUF2,INO80E,PHC2,TERF2IP,AHCTF1,SP100,UCHL5,NUP107,NSFL1C,NABP1,ATF2,CDK12,RNF169,DCTN1,BRD4,RFC3,HMGN4,WBP2,CDCA2,NUSAP1,MEF2D,POLG2,H2AFV,GAR1,TRIM28,CENPU,SUPT16H,PPP2CA,RAD51C,DSN1,PPP2R5A,NSMCE2,H2AFX,STAT1,BEND3,XRCC4,DYNC1LI2,POLQ,PRPF4B,NCOR2,MECP2,TCF3,BLM,SPDL1,RFWD3,RPA2,CAPN2,ADD3,SUV39H2,CITED2,CREB1,MSH6,SMC4,KAT2A,POLK,LLPH,CBX3,RPA1,KIF18A,C1orf131,POLE,LRPPRC,PML,HMGB2,PURA,IPO4,DDB1,POLA2,SKA3,THOC1,KMT2E,CSNK2A1,SIRT2,KIF2C,BIRC2,MBD4,TET3,PCNA,XRCC2,KIF22,MCMBP,PLK1,BAZ2A,RAD51AP1,WDR82,BRCA1,PBRM1,ASF1B,CHAF1A,FBXO28,CHD3,TONSL,E2F4,BAZ1B,ACTB,CHEK2,SINHCAF,FAM208A,POT1,CCDC137,NSMCE4A,PPP1R12A,HJURP,CENPF,CTCF,MEF2A,CDK13,ASXL2,ARID1B,DTL,RB1,MBD2,BANF1,XPA,BUD31,TIMELESS,CTR9,ICE2,KIFAP3,KNTC1,HP1BP3,LDB1,SEPT7,APPL1,PAXX,NSMF,CDCA5,RUVBL2,RBBP4,SMARCD1,MBD1,TCF12,USP7,CHMP2A,ASH1L,MPHOSPH8,DYNLL1,SMARCA4,NSD3,ORC1,MXD1,MEAF6,HNRNPA2B1,OIP5,SAP130,KMT5C,CD3EAP,AKAP8,TARDBP,TOP1MT,UTP4,SPIDR,HTRA2,PRPF19,KDM3B,FAM172A,NFATC2,DCLRE1C,KDM1B,MBD3,RBL1,STAT6,UHRF2,XRCC3,ANP32E,NCOA1,H3F3A,USP11,SMAD4,RAD51D,NIFK,MCM10,SHPRH,CDT1,DCTN2,CDCA8,SMC6,HMGN3,PAWR,CSNK1A1,NCAPG,WRNIP1,IRF4,KMT5A,NABP2,H2AFY,SS18L1,PTGES3,CENPM,ORC3,FBL,STAT3,GINS1,TELO2,HMGN1,HMGN5,NASP,PRKDC,HELB,TOP3A,POLR3GL,RANGAP1,MEN1,ZFR,LEMD2,UPF1,BIRC5,ZNF330,E2F1,CENPT,MBD6,CHMP7,TERF1,SLF2 |
| 8.795e-30 | -66.90 | GRAESSMANN_APOPTOSIS_BY_DOXORUBICIN_DN | MSigDB lists | GRAESSMANN_APOPTOSIS_BY_DOXORUBICIN_DN | 1664 | 419 | 17377 | 2626 |
RAB14,ADAM10,CXXC1,TMEM109,XIAP,AP3M2,YTHDF3,LACTB2,CNTROB,EEF2K,CALM2,RABGAP1L,RAB4A,RAD23B,ATP13A3,FBXW2,AP2B1,SUCLG2,SMARCE1,ZNRD1,SENP1,SEH1L,SRSF10,USP34,NRAS,AATF,GABPA,PBK,MKI67,NUTF2,GALNT7,USP22,MCM2,STOML2,ZMYM3,MAP3K4,MID1IP1,RAD18,LIMK1,WDR4,OGT,ATE1,ARRB2,PFKP,PTOV1,PRPF38B,EWSR1,KRBA1,DHPS,ANKH,TRIO,CUTA,DHX9,RRM1,NOTCH2,PMF1,EZH1,PRPF39,PARN,COPG2,MYL6B,CDC73,NDUFS7,TMEM179B,C12orf10,TFAP4,EIF2S2,EXOSC7,KLHL5,INTS7,SNX18,HDAC7,ATP6V0A2,FOXN2,TNPO3,MRPL40,LPCAT1,NSUN4,LUC7L2,FDFT1,PRIM2,BCLAF1,GORASP2,TOMM40,ELK1,XRCC5,PTPRF,CAT,MTHFD2,HSPBP1,KPNA1,CEBPG,PIAS2,CNOT6,TCOF1,MAP3K5,RUFY3,CDK2,SNX14,MRPL3,ZC3HAV1,EGLN1,ZNF207,SARNP,IVNS1ABP,UBR2,SUZ12,RAF1,CHD1L,OLA1,VTI1A,NUF2,TCF19,LCLAT1,REPS1,KIAA1147,PRKD3,AHCTF1,ATP2A2,MTMR4,NUP107,SOCS6,NSFL1C,CDKN1B,BRI3,TTC3,ATF2,ILKAP,CPNE1,MAPRE2,BRD4,EID1,KAT7,TAOK1,CUL3,ATP6V0A1,ELP4,NUSAP1,TANC1,ERC1,DDX17,AMZ2,KIF2A,CHCHD3,RAD51C,ZNF282,HSPA4,DGCR8,HIPK2,NSMCE2,LMBR1,RBMS1,MBOAT1,ATF6,XRCC4,COIL,CSNK1D,TUBB,GALK1,PKP4,ZNF445,ANXA6,ZFP91,SRSF6,MECP2,TCF3,TRAK1,FLOT1,MYNN,ARGLU1,ETS1,POFUT1,MAD2L2,KRI1,ZBTB45,ADD3,NDUFB4,HUWE1,FJX1,FUT8,PTPN11,DCP1A,GEMIN6,CREB1,CNOT6L,IFT46,RPL22L1,SPTAN1,PPP3CA,TK1,KAT2A,NET1,NEK7,ILF3,JTB,TBRG4,RABIF,KLF6,KIF11,CBX3,SH3BP5,GNA12,FBXO21,SLC19A1,KEAP1,POLE,FAM3C,HMGB2,DUSP11,YWHAH,PURA,ANAPC4,BYSL,SNAPIN,ZBED3,PTMS,UBE2E2,ST13,NF1,SNX15,ENSA,DNAJC24,CSNK2A1,SND1,MRPL19,FANCI,SSR1,PRNP,PAPOLA,DST,FANCL,IL6ST,SLC44A1,ZBTB22,RP2,MCMBP,OGG1,MRPL32,DRAM2,CARM1,SRPK2,PTPRK,SP3,METTL1,TDP1,MIOS,FOPNL,LRBA,MRPL12,TMEM216,GMFB,SREK1,PSMG1,WDR82,CDC6,PITPNB,PBRM1,ANLN,KRTCAP2,PRPSAP1,USP21,ALG3,TBC1D17,BRWD1,NRM,IARS2,PQBP1,ACTB,CHEK2,ROCK1,DCAF5,POT1,NUMB,FUBP1,UBE2D3,NSMCE4A,ZCCHC8,ZNF768,UFC1,NKD2,TIA1,KLC1,CTCF,MEF2A,RACGAP1,THRAP3,XPO7,LYRM2,RHBDD1,DTL,NFATC3,VASP,MBD2,XPA,CAPZA1,TIMELESS,AHDC1,MDFIC,BCL2,ALDH18A1,KDELR1,ABCC1,HP1BP3,POLR2I,ERLIN1,NUDT4,DCAF8,KRAS,MAP4K3,UBE4B,METTL22,ZDHHC3,PCM1,GALNT2,SYNCRIP,TMEM168,CDC27,RBM25,EXOC4,SIL1,FAM122A,PRMT7,YWHAZ,ZFP90,MYO9A,TSEN15,BCCIP,TCF12,MMACHC,IMMT,ASH1L,FEZ2,GNPNAT1,FOXM1,UCK2,TM9SF3,IRF3,DUSP22,CHD1,RAD23A,CSDE1,MRPL50,NRF1,PDK2,IARS,CCDC50,EXOSC1,AKAP8,MRPL34,SCAMP4,CYB5R1,APOOL,MINPP1,CTDSP2,RLIM,MND1,NXT1,BOLA1,CADM1,MBD3,USP36,SRSF1,CCDC127,IDE,HNRNPR,RBL1,STAT6,FASTK,LTA4H,SMAD4,TSPAN5,PARD3,C19orf53,GOLIM4,RRP15,MRPL42,PDAP1,DAP,DBF4,SMC6,LETMD1,KLF13,CHAC2,TFRC,XPR1,KIF5B,GART,KLHL20,RRBP1,NDUFS8,POLR1B,ERI3,ORC3,CAMK2G,ELOVL5,ADAM17,NASP,TMEM39A,PRKDC,COG1,ARHGEF12,PRMT2,RHOT2,SNRPA,TARS,MAPK3,MTMR3,RAB18,TPD52L2,ELMO1,NEIL3,CDCA7L,CTBS,BBX,GLG1,SPCS3,SRSF3,UBE2C,GCSH |
| 1.365e-29 | -66.46 | JOHNSTONE_PARVB_TARGETS_3_DN | MSigDB lists | JOHNSTONE_PARVB_TARGETS_3_DN | 829 | 250 | 17377 | 2626 |
TMED7,SKA3,MRPS15,YTHDC2,DNAJC24,EBNA1BP2,GLUD1,ABCB10,KIF2C,CDC42SE2,BRIX1,EIF1B,MAP1LC3B,CMTM6,FANCI,SSR1,CREM,FANCL,CDKN2C,PCNA,NOL11,ATG3,ZNF639,RABGAP1L,SRSF4,PDS5B,TRA2B,CISD2,RP2,TCEA1,SPTSSA,EIF5,MYBL1,ZNRD1,TIPARP,MTPN,SEH1L,CCAR1,RYBP,USP34,COPS8,ZNF559,CCDC138,NCK1,FOPNL,PBK,MBLAC2,RAD51AP1,KIF15,RRM2,WDHD1,MCL1,CDC6,SMC2,NUTF2,PRKRA,CBFB,RFC2,ODC1,DHX15,RHEB,IWS1,C1orf122,BRD2,STT3A,NIP7,ZNF367,U2SURP,OGT,BEND6,SASS6,MRPL13,ATP6V0E1,SMNDC1,STARD3NL,FUBP1,WSB2,RECQL,EWSR1,CENPF,RRM1,KIF23,RACGAP1,PM20D2,NCKAP1,PITHD1,RAPGEF6,SPAG5,MCTS1,DTL,C1GALT1,SUB1,SMC3,KLHL5,MBD2,MEA1,MSH2,FOXN2,ALDH18A1,N4BP2,EEF1D,LUC7L2,HP1BP3,MORC3,IFRD1,ELL2,DHX29,OXR1,UTP15,GTPBP4,GORASP2,RIT1,ARID1A,SEPT7,C9orf40,CYB5A,PHF6,MASTL,SERTAD2,OSBPL11,MTHFD2,SYNCRIP,UAP1,KLHL15,PRPS2,RUVBL2,SNRNP70,RUFY3,TSEN15,N4BP2L2,TCF12,FAM208B,NQO1,RPLP2,IVNS1ABP,RAC1,PTTG1,TMX4,TMEM97,NUF2,POMP,TCF19,STMN1,RPAIN,KTN1,ANKRD28,OIP5,NUDT19,APLP2,PRKD3,UBXN2A,CCNA2,IARS,SAR1A,NUP107,SOCS6,PARL,FAM76B,RNASEH2A,CHTOP,PDIA6,RBM15,ATF2,EBAG9,HMGN4,PPT1,PGGT1B,GOPC,TAOK1,CUL3,RPL38,PFKFB3,TOR1AIP2,KIAA1586,NUSAP1,GLO1,AZI2,HERPUD2,H2AFV,SHCBP1,TXNL4A,SERP1,KIF2A,CCDC14,RBL1,HNRNPR,TIMM17A,NDUFA11,RBMS1,ANP32E,FKBP5,XRCC4,GOLIM4,MZT1,DBF4,CDCA8,FLOT1,NUP54,ARGLU1,CSNK1A1,NCAPG,SLC25A43,RMI1,FBXO5,RBM17,RPA2,SUV39H2,KLHL20,PTEN,CWC27,PPP1R8,PRC1,NAA50,CENPM,CNOT6L,TMX1,HNRNPM,MSH6,MYO5A,SMC4,GINS1,TSHZ1,YTHDC1,PPP3CA,HMGN1,TK1,HMGN5,ASPM,PRKDC,ZMYM5,MRS2,ATP2C1,RFFL,ARHGEF12,RHOT1,KIF11,RPA1,RAB18,KIF18A,ATAD2,TWSG1,BIRC5,ZNF330,TFDP1,CDCA7L,MAPK6,C4orf46,SRSF3,WDR76,THAP5 |
| 2.136e-29 | -66.02 | RNA metabolic process | biological process | GO:0016070 | 3470 | 747 | 17256 | 2622 |
ZBTB10,KDM4A,DHX8,LACTB2,CCNL2,EDRF1,RBM4,ZNF275,PABPC4,RPL23A,USF1,CIPC,NSRP1,SRSF4,CRY2,ECD,ZNRD1,FTSJ3,PCBP2,ZNF672,ZNF559,GABPA,HNRNPF,WDHD1,MIER2,TOPORS,DIDO1,BRMS1,SMAD2,RPS27A,ZNF689,VIPAS39,RNASEL,SMG9,TFDP2,SMAD1,E2F2,ZNF75A,SMNDC1,SLC25A33,DDX42,SSRP1,HIVEP3,DHX9,EZH1,PDCD7,PARN,CDC73,MCTS1,RAVER2,TFAP4,DDX56,INTS7,EFTUD2,ZNF326,RTCB,FOXN2,GEMIN4,CPSF4,PABPC1,NSUN4,PPA1,LUC7L2,CARS2,SRSF11,AGGF1,ETV3,FOXK1,RB1CC1,DHX29,ZMYND11,SF3B6,TEX10,TYW1,GTPBP4,RPS10,MYBL2,BCLAF1,SRSF5,CBFA2T2,ELK1,POLR2J,ETS2,SETD3,TYW5,CNOT6,ZNF830,SGF29,ZNF296,KARS,SARNP,TRERF1,IVNS1ABP,PTTG1,CREBL2,ZNF267,INO80E,SAFB2,PRKACA,RCOR3,TCF19,APP,RBM23,ZNF420,SP100,UTP18,ZKSCAN1,MTA1,GRSF1,GMEB1,NABP1,INTS12,ZNF226,ATF2,RBM15,ZC3H3,RPRD1B,CGGBP1,CPNE1,POLR2L,EID1,KAT7,INTS13,CRNKL1,WBP2,RPL38,POLR2D,RNPS1,E2F3,MEF2D,DDX17,TAF2,PPP2CA,CHCHD3,LSM6,HIPK2,NT5C3B,RPLP1,RBMS1,FUS,SNRPG,PPP5C,ZBTB11,COMMD10,ZNF786,RPS2,ZNF445,SRSF6,TRMT6,HABP4,JMJD6,WDR5,ETS1,NEXMIF,RRP36,PNO1,ZNF92,TUT4,KRI1,ZBTB45,GATC,SUV39H2,PPP1R8,PRDM4,ZNF260,DCP1A,GEMIN6,ZNF710,GTF2H2,HNRNPM,MED22,PDPK1,DDX24,ZNF512,DDX39A,UTP20,ZNF180,ZNF862,KEAP1,POLE,PITX1,LRPPRC,PML,HMGB2,USF2,THAP5,DDX47,THOC1,GPBP1L1,YTHDC2,RBM8A,CSNK2A1,EBNA1BP2,SND1,BIRC2,PAPOLA,CREM,KRR1,LIN9,PCNA,GLIS2,ZNF639,INTS1,ETV6,TRMU,POP7,NOC2L,MYBL1,CCAR1,RYBP,SP3,METTL1,RPP25,EXOSC6,HARS,BAZ2A,SNRPB,MRPL12,PBRM1,EAF2,UTP3,BRCA1,PRKRA,LUC7L,USP21,CHD3,ZNF367,E2F4,QRSL1,PRPF4,DVL1,OSGEPL1,ZNF45,BEND6,FAM208A,GEMIN7,ZNF564,FUBP1,SEPHS2,CTU2,ZCCHC9,PHB2,CTCF,CHCHD2,CDK13,RLF,ASXL2,CNOT11,ARID1B,SNRNP25,SUB1,RB1,MLX,MED8,MBD2,CMTR2,SSBP3,ZNF746,CTR9,TIMELESS,MDFIC,RBM3,ICE2,MAML1,PREB,LDB1,UTP15,RTF1,ZNF761,RBM38,IRF5,ZNF174,RXRB,RPL36,SYNCRIP,TBPL1,PRMT7,DTD1,RUVBL2,SART1,TRAF7,RPLP2,ARID2,FOXM1,MRPL39,DYNLL1,XAB2,LAGE3,ZNF416,RRAGC,PCBP1,COMMD8,ZNF121,RPL11,CSDE1,NRF1,ZBTB21,ZNF473,KMT5C,DUS4L,ZNF302,RPAP1,TARDBP,AHCYL1,STRAP,SAP30L,ZNF583,DVL2,PRPF19,KDM3B,RPL29,RPL35,POLR2G,ZNF780B,BTG2,PPIE,NFATC2,PRPF3,KDM1B,TXNL4A,RPSA,SRSF1,SUGP1,DHX16,ZNF700,RBL1,MAFK,ZNF436,DNAJC17,NCOA1,SMAD4,INTS2,SLC30A9,CTDP1,NIFK,CDC40,MTERF1,RRP15,AGO2,ARID5A,GTF3A,NKRF,PAGR1,GTPBP3,IRF4,CWC27,DDX31,SS18L1,POLR1B,RBM15B,YTHDC1,RPRD1A,HMGN5,ZNF202,ZMYM5,PPWD1,PCGF1,DDX23,BIRC5,L3MBTL3,TFE3,CDCA7L,BBX,E2F1,RBPJ,TAF12,NR2F2,HIPK3,IFI16,TXN,ZNF496,MAX,CXXC1,USP39,CCNB1,COMMD6,POLR3K,MYEF2,UTP25,PA2G4,SNUPN,NOL11,FIZ1,RNASEK,ZNF200,TRA2B,TAF5L,DNMT1,ZNF800,CDC5L,SRSF10,ZNF524,KLF10,NOL8,NSUN2,ELOA,DDX20,USP22,CBFB,MAK16,CLNS1A,PRIM1,IWS1,HHEX,RBM47,BRD2,LUC7L3,RPS14,WDR4,BTF3,RRS1,ARRB2,CCDC59,HDAC2,PTOV1,PRPF38B,EWSR1,LIME1,POLR2K,PRKAA1,GSPT2,NOTCH2,PMF1,SUPT7L,PRPF39,ZNF518A,ZNF79,METTL3,VPS25,CNOT3,YY1AP1,EXOSC7,LHX8,KLF16,HDAC7,MRM3,EEF1D,PHF10,DDX28,ZNF84,PRIM2,ELL2,ZNF574,RPS24,EXOSC9,ARID1A,KDM3A,PATL1,SF3A2,TWISTNB,PHF6,XRCC5,EPRS,ZNF777,SERTAD2,ZFP92,RBMX,QARS,MED15,CEBPG,PIAS2,YY1,RNF14,NRBP1,ZNF511,TP53RK,ATXN3,ZBTB37,SF3B1,SUZ12,C2orf49,TERF2IP,SPINDOC,ZNF75D,KDM2A,UCHL5,LPIN2,RNASEH2A,AQR,CDK12,MRM2,SAP30,BRD4,ERF,DRAP1,SLBP,ELP4,EDF1,POLG2,GAR1,TRIM28,CENPU,DHX57,PRDM11,SUPT16H,NSA2,VEZF1,ZNF282,HINT1,DGCR8,SAFB,TBL3,STAT1,FTSJ1,PPA2,ATF6,BEND3,PDCD11,EYA2,ATMIN,CSNK1D,PRPF4B,POU3F2,NCOR2,DEPDC1,TWNK,MECP2,TCF3,MYNN,ARGLU1,FOXO3,HMG20A,MAD2L2,WWP2,GTF2F1,RBM17,CCNK,DNAJC8,RPL17,ELP5,RPL19,UPF2,CARF,CITED2,CREB1,CNOT6L,NCOA2,TSHZ1,ZFP64,KAT2A,RNASEH2C,TRIR,WDR18,ILF3,RPL8,RFXANK,TBRG4,BMS1,RPL27A,COMMD4,KLF6,TSR2,POLR2A,CBX3,RPL32,ZHX1,HNRNPH3,TFDP1,KHSRP,DDX5,DUSP11,WDR62,TAF6,PURA,BYSL,DDX52,RORB,CCNC,ZNF76,IER2,NOP2,KMT2E,PHRF1,ALKBH5,ZNF107,SIRT2,TAF6L,SNRPD3,COMMD5,MAPK14,SNAPC4,ZNF696,EDC3,SF3B2,EIF4A3,THADA,JAZF1,METTL14,PHTF1,RPF2,KHDC4,GPATCH1,ZBTB22,TCEA1,ARID4A,CARM1,ELOF1,SRPK2,LARS,DEAF1,SNRNP200,RIOX2,SREK1,SOX4,KMT2C,ASF1B,DHX15,RPL37,GEMIN5,UBTF,PAF1,BRWD1,U2SURP,IARS2,PQBP1,CRCP,BAZ1B,ZNF268,CHEK2,RPS26,RPS15,ZCCHC8,ZNF768,NACA,MED13L,RPL15,MEF2A,THRAP3,SRRT,TTF1,PRPF18,LYAR,NFATC3,ZNF449,MED10,BUD31,ZNF335,YBX1,ACAD8,ZNF189,VOPP1,POLR2I,CIC,SUGP2,RPL6,SLTM,DAPK3,RBM25,NFIL3,NUP62,TRMT10B,ZFP90,SNRNP70,RBBP4,HNRNPDL,TSEN15,ADNP2,ZBTB24,TCF12,MBD1,ASH1L,MPHOSPH8,CHERP,SMARCA4,PLAGL2,NSD3,IRF3,CHD1,MXD1,PAIP1,MEAF6,HNRNPA2B1,SAP130,FARSA,RRN3,IARS,CD3EAP,EXOSC1,AKAP8,CHTOP,UTP4,ZNF770,RLIM,CSTF1,POU2AF1,ZNF500,METTL2A,SMU1,PCGF6,ATXN1,LSM8,BUD13,MBD3,RPS9,ZNF317,DUS3L,HNRNPR,STAT6,ARNTL,AKNA,MAPK1,BRD9,CBX4,CWC25,NAT14,DNAJC2,ZNF316,EYA1,SCYL1,KLF13,PAWR,MXD4,CTNNBL1,KMT5A,PPIG,PELO,DUS2,NABP2,ANP32A,BRD7,FBL,STAT3,SAMD4B,GTF3C6,PPP1R9B,PSPC1,HELB,MIER1,POLR3GL,RCOR1,MEN1,ZNF407,SYMPK,SNRPA,TARS,MAPK3,TFEB,HSPA1B,CNOT9,UPF1,ATAD2,ZC3H7B,KMT2B,ZRANB2,SRSF3,ZMIZ1,TYW1B |
| 9.312e-29 | -64.54 | cellular response to stress | biological process | GO:0033554 | 1631 | 411 | 17256 | 2622 |
TXN,MAX,ADD1,CXXC1,TMEM109,XIAP,CUL1,CCNB1,UBE2I,RBM4,PARK7,FBXO22,EEF2K,PSMD1,PARPBP,RAD23B,PDS5B,DNM2,FNIP2,CRY2,SEH1L,CDC5L,PLK3,BAK1,PGAP2,ERCC1,AATF,KLF10,MRNIP,WDHD1,TOPORS,MCL1,RFC2,GINS4,PLEKHF2,STOML2,DOT1L,MAP3K4,RAD18,RPS27A,PSMD8,AXIN1,PRDX5,MPV17,TFDP2,SLF1,ZMAT3,HDAC2,SSRP1,HSPH1,RECQL,CLSPN,SEC61G,POLR2K,MUM1,PRKAA1,PXMP2,CYCS,EIF2AK4,PSEN1,PSMD9,METTL3,WDR48,JMY,NPLOC4,CNOT3,LMNA,DDRGK1,MCTS1,CFLAR,TFAP4,RNF121,SMC3,INTS7,MSH2,DAPK1,MYDGF,TERF2,SOCS5,MAN1B1,ERO1A,USP10,ARMT1,BCLAF1,MPG,MTR,MAP2K2,RHOB,PSMB3,FAS,XRCC5,PTPRF,DERL1,SEC31A,CAT,POLR2J,CNOT6,MAP3K5,YY1,ZNF830,CDK2,RNF139,CDKN2A,EGLN1,ATXN3,DNMT3A,RWDD1,NQO1,RPS6KA1,CHD1L,PTTG1,RMI2,BCL2L1,INO80E,PRKACA,TERF2IP,MOAP1,CRKL,CCNA2,ATP2A2,SHC1,SP100,KDM2A,RALB,UCHL5,MTA1,UBA5,NABP1,CDKN1B,RNASEH2A,CEP63,AQR,ATF2,RNF169,DCTN1,ULK3,CDKN2AIP,SEC61B,RFC3,BRD4,POLR2L,KAT7,MAP4K4,TAOK1,POLR2D,CUL3,DNAJA1,POLG2,PSMB9,TRIM28,SERP1,SUPT16H,ANKZF1,RAD51C,ALDH3B1,HSPA4,SEC61A1,GUCY1B1,NSMCE2,HIPK2,FAAP100,SEL1L,H2AFX,ATF6,PPP5C,XRCC4,GEN1,EYA2,ATMIN,USP13,POLQ,CCM2,BABAM1,FLOT1,SDF2L1,UBE4A,BLM,ETS1,FOXO3,MAD2L2,NEXMIF,NEIL2,SRXN1,CCNK,RBM17,RFWD3,RPA2,PSMD2,PDCD10,SUV39H2,PTEN,HUWE1,CENPJ,PTPN11,GTSE1,COPS7B,CITED2,MAP3K14,CNOT6L,GTF2H2,TMX1,MSH6,STAU1,TNFAIP3,POLK,NET1,PARP4,DDX39A,POLR2A,PRDX1,SH3GLB1,RPA1,YIF1A,POLE,GPS2,PRDX3,TATDN2,TFDP1,PML,AEN,HMGB2,ASNA1,WDR76,CPEB2,DDB1,UBE2E2,NF1,PPP1R15B,FAM129A,ALKBH5,SLC29A1,SIRT2,UBQLN2,BECN1,MAPK14,MAP1LC3B,RNF103,FANCI,MBD4,SSR1,FANCL,CYREN,PCNA,RCSD1,XRCC2,PIK3R2,AKR1B1,KIF22,TCEA1,OGG1,CARM1,CDC37,PTPRK,PLK1,COPS8,TDP1,LARS,MIOS,RBX1,NCK1,RAD51AP1,VHL,TLK1,UBE2V1,BRCA1,SOX4,PRKRA,OPTN,CHAF1A,TONSL,E2F4,BAZ1B,CAB39,STK11,CHEK2,COPS6,PSMC1,UBE2D3,NSMCE4A,TMUB1,PHB2,UFC1,CIB1,CDIP1,DNAJB1,CNOT11,PITHD1,RHBDD1,DTL,TIGAR,XPA,TIMELESS,BCL2,MDFIC,ATP6V0D1,PREB,HP1BP3,ATP5IF1,POLR2I,ERLIN1,OXR1,GBA,PSMA1,EIF2AK1,MAP4K3,UBE4B,EIF2A,SYVN1,ISG15,PSMC4,MASTL,MBIP,PAXX,PALB2,KLHL15,CDCA5,RUVBL2,ECPAS,ADNP2,BCCIP,USP7,FOXM1,XAB2,SUMO2,SLC2A1,TMX4,PMS2,RRAGC,IRF3,LYN,RPAIN,RAD23A,PDK2,ANKLE1,BABAM2,MDM2,PSMA6,TARDBP,PDIA6,CTDSP2,SPIDR,HTRA2,PRPF19,PPIF,MND1,POLR2G,CGAS,PSMA8,BTG2,PPIE,PSMB7,NFATC2,DCLRE1C,EDEM2,FANCE,RAD54B,DNAJC10,SCAP,TAB2,PSMD3,STAT6,WDR59,ARNTL,XRCC3,SMURF1,MAPK1,RAD51D,TMEM33,SLC30A9,MIF,MCM10,TRIP12,SH2D3A,DAP,EYA1,SHPRH,MRPS26,TMX3,SMC6,PAGR1,RMI1,DNAJB9,WRNIP1,TANK,NABP2,ARHGEF2,ATG13,RNF5,TXNL1,HMGN1,RHOA,HELB,PRKDC,TOP3A,MEN1,CHCHD6,HSPA1B,MFN2,MAPK3,CNOT9,MTMR3,PDCD6,UPF1,NEK1,NEIL3,E2F1,PKD2,RBPJ,SLF2,HRAS,IFI16 |
| 1.486e-28 | -64.08 | SPIELMAN_LYMPHOBLAST_EUROPEAN_VS_ASIAN_DN | MSigDB lists | SPIELMAN_LYMPHOBLAST_EUROPEAN_VS_ASIAN_DN | 565 | 189 | 17377 | 2626 |
CCNC,ST13,COPA,FAM129A,XIAP,CUL1,TGOLN2,BECN1,MAP1LC3B,BIRC2,MBD4,CREM,SNUPN,HADHB,AP2B1,TFG,EIF5,SRP72,KLF10,NCK1,LAP3,GABPA,SNRPB,GMFB,MCL1,SLC17A5,PITPNB,UTP3,MCM2,SLC25A5,PRPSAP1,ODC1,DHX15,ARF4,OPTN,STOML2,TRAM2,SMAD2,TMED10,PTER,PRPF4,ZNF45,ATP6V0E1,NMD3,PFKP,ANXA11,SLC12A7,UBE2D3,MAPRE1,PPP1R2,LAMTOR3,ASAH1,RPL15,PPP3CB,TMED3,CRLF3,PRPF18,COPB2,NDUFS4,CFLAR,CD59,NFATC3,EIF2S2,ARPC5,KIFAP3,RBM3,GEMIN4,CPSF4,SLC12A2,PPA1,TSPAN31,GTPBP4,PSMA1,SSR2,RIT1,ICAM2,RHOB,NMT2,FAS,CAT,GOLGA4,CDC27,NSF,ERGIC3,NFIL3,COX7A2L,SIAH2,PITPNA,YWHAZ,PDLIM5,PTDSS1,RNF139,EGLN1,WASF2,ZNF207,PRKAB1,TOMM20,UGP2,SF3B1,MDH2,RRAGC,CREBL2,CHKB,DAZAP2,ATP6V1B2,PCBP1,CSDE1,TNFAIP8,RALB,UCHL5,GRSF1,NSFL1C,RPN2,TTC3,LMAN1,ARL5A,CTDSP2,CGGBP1,ATP6V1G1,CCT2,CLCN3,MKLN1,HMGN4,PPT1,CDC123,BTG2,PPIE,POLR2D,ATXN1,DNAJA1,CDC23,RAB1A,VDAC1,PSMB9,PDHX,KIF2A,DAP3,CDC16,JAK1,DDOST,GOLGA8A,TIMM17A,SEL1L,SMAD4,CBX4,SCAMP3,SRSF6,ARFIP2,GMCL1,CSNK1A1,DNAJB9,RPA2,KIF5B,CTSS,PDCD10,PTEN,PPP1R8,ANP32A,CREB1,STAT3,MYO5A,TMX1,YTHDC1,DDX24,GALC,PARP4,JTB,TBRG4,RABIF,KLF6,PDE3B,PICALM,NEU1,ZFR,ATP6V1D,PDCD6,GOLGA7,PRDX3,CCDC6,MFAP1,CTBS,OAZ2,CAPN7,PGRMC1,GLG1,RBPJ,PSAP,IDH3B,DDB1 |
| 1.530e-28 | -64.05 | RNF2 (ring finger protein 2) | protein interactions | 6045 | 723 | 235 | 17029 | 2761 |
UBE2E2,MAX,HNRNPAB,COPA,NOP2,THOC1,CXXC1,RBM8A,MCCC1,CSNK2A1,SNRPD3,SEC16A,BECN1,MYEF2,PABPC4,RPL23A,SF3B2,KRR1,NOL11,EIF4A3,PDS5B,NOC2L,RPF2,TECR,SMARCE1,FTSJ3,TRIM14,TIMM50,SRSF10,CDC5L,RYBP,SRP72,FYTTD1,SNRNP200,PBXIP1,LAP3,SLC25A22,UBE2V1,MIER2,OGFR,EIF3A,ZMYM3,UBTF,RBM47,TMED10,CHD3,LUC7L3,BAZ1B,ADAM9,FAM208A,SINHCAF,RPS26,HDAC2,SSRP1,UBE2D3,RPS15,PARP12,EWSR1,ZCCHC8,PHB2,DHX9,RRM1,RPL15,NDUFA4,CDK13,THRAP3,PDXDC1,MYL6B,NUP205,COPB2,FBRS,LYAR,RPN1,DDX56,SMC3,EIF2S2,MCM5,EFTUD2,ZNF326,YBX1,GLE1,MRPL48,GNAI2,LUC7L2,EEF1D,HP1BP3,EIF3L,MAPKAPK3,MTA2,TEX10,SUGP2,RPS10,RPL6,UTP15,GTPBP4,ITM2A,RPS24,BCLAF1,ABCF1,PSMC4,XRCC5,RPL36,MAGED2,EPRS,SYNCRIP,NSF,QARS,RBMX,RUVBL2,YY1,PPP6R3,SNRNP70,RBBP4,HNRNPDL,PDLIM5,PTDSS1,ZC3HAV1,CDKN2A,RNF114,USP7,MBD1,SART1,TRIM41,XAB2,SUZ12,SF3B1,EIF3D,HNRNPUL2,ANK3,SMARCA4,LCLAT1,APP,PHC2,SEC11A,MDM2,PSMA6,ATP2A2,STRBP,SIAH1,CD3EAP,UTP18,MTA1,AKAP8,PPP6C,TARDBP,AQR,APOOL,CHTOP,CLN6,UTP4,PRPF19,RPL29,POLR2G,KAT7,PCGF6,RPL38,CRNKL1,RNPS1,CIRBP,GAR1,TRIM28,RPSA,SRSF1,SUPT16H,CHCHD3,NSA2,HNRNPR,RPLP1,H2AFX,H3F3A,USP11,PDCD11,CBX4,LRCH1,DNAJC2,NIFK,RPS2,NDUFS1,ZFP91,TMX3,MRPS26,CBLL1,ATP5F1B,WDR5,TFRC,PNO1,ERH,ADD3,RPL17,H2AFY,DDX31,RPL19,FBL,MRPL11,SMC4,LDHB,PPP1R9B,ZFP64,CSRP1,DDX24,TIMMDC1,ZNF512,ATP2C1,TUFM,LDHA,ILF3,RANGAP1,BMS1,PCGF1,RPL27A,RHOT2,TARS,SNRPA,ZFR,HSPA1B,RPA1,CBX3,UPF1,TRIM26,PLAA,RPL32,MAGT1,MFAP1,HNRNPH3,TFDP1,LRPPRC,GLG1,KHSRP,DDX5,SRSF3,TERF1,IPO4,GPATCH4,BYSL,DDX52 |
| 1.666e-28 | -63.96 | cell cycle process | biological process | GO:0022402 | 1003 | 285 | 17256 | 2622 |
FGFR1OP,NUP188,MAX,PDCD6IP,TSC2,XIAP,CUL1,CNTROB,CCNB1,MIS12,KIFC1,CDKN2C,PA2G4,NEK6,PDS5B,DNM2,NUP153,CDC25B,SEH1L,MLST8,PLK3,ERCC1,NSUN2,MRNIP,SMC2,AURKB,CCNF,MCM2,RFC2,PRIM1,KIF18B,RPS27A,MAP4,ITGB1,RRS1,TFDP2,AAAS,ANXA11,MAPRE1,CLSPN,PHF23,RHOC,PRKAA1,KIF23,TOP2B,HAUS4,EIF2AK4,PMF1,NOTCH2,HAUS2,LMNA,SPAG5,CNOT3,JMY,RTKN,TMEM250,SMC3,SNX18,MCM5,MSH2,FBXL7,NUP85,PRIM2,MYBL2,SEPT8,RHOB,GOLGA2,FAM83D,ARAP1,CNOT6,NDE1,ZNF830,CDK2,NUP58,CDKN2A,ZNF207,NDC1,UBR2,POC1A,PTTG1,ANK3,ACTR3,TPX2,MYH9,NUF2,BCL2L1,PRKACA,STMN1,CCNA2,AHCTF1,NUP107,NABP1,SEPT11,CDKN1B,CEP63,ATF2,CFL1,DCTN1,ANKLE2,PSRC1,BRD4,RFC3,CDC123,INTS13,TAOK1,CUL3,SLBP,NUSAP1,PKMYT1,CDC23,CENPU,TAF2,PPP2CA,KIF2A,RAD51C,CHMP4A,DSN1,GOLGA8A,CSNK1D,TUBB,DYNC1LI2,MZT1,MECP2,BLM,SPDL1,RAB11A,MAD2L2,SAPCD2,RFWD3,RPA2,CENPJ,PRC1,NAA50,GTSE1,CNOT6L,MSH6,SMC4,NUDC,PPP3CA,NEK7,WDR18,JTB,TBRG4,KIF11,RPA1,KIF18A,POLE,TFDP1,PML,CCDC69,SSNA1,WDR62,ESPL1,POLA2,GPR132,KMT2E,ENSA,KIF2C,BECN1,BIRC2,FANCI,PRNP,RAB8A,NUP210,PCNA,RAB35,XRCC2,KIF22,MYBL1,MCMBP,CARM1,TACC3,PLK1,SEPT9,RRM2,EZR,CDC6,BRCA1,SOX4,ANLN,RHEB,OPTN,SEPT1,CHD3,E2F4,PPM1G,CAB39,STK11,CHEK2,VPS4A,SASS6,PPP1R12A,PHB2,CENPF,LAMTOR3,RACGAP1,CRLF3,CNOT11,NUP205,RB1,CCP110,BANF1,TIMELESS,KNTC1,MCPH1,SEPT7,EIF4G2,MASTL,HAUS8,TSC1,PCM1,CDC27,LAMTOR4,CDCA5,ODF2,SLC16A1,NUP62,CCNB2,BCCIP,CHMP2A,PRKAB1,FOXM1,DYNLL1,RRAGC,ORC1,ANKLE1,MDM2,ABRAXAS2,PPME1,KIF14,AKAP8,PPP6C,MND1,BIRC3,BTG2,TUBGCP5,NUP155,CHMP2B,RAD54B,CEP55,CHMP4B,XRCC3,GAS2,REEP4,PPP2R2D,RAD51D,KIF3B,CTDP1,MCM10,RAE1,CDT1,DCTN2,NUP54,DBF4,CDCA8,NCAPG,TUBGCP2,FBXO5,STARD9,NABP2,ARHGEF2,CENPM,ORC3,CAMK2G,TGFB1,GINS1,PPP1R9B,RHOA,NASP,PRKDC,ASPM,RANGAP1,BORA,MFN2,CNOT9,LEMD2,UPF1,BIRC5,E2F1,PKD2,CENPT,UBE2C,CHMP7,TERF1,HRAS |
| 1.973e-28 | -63.79 | FEVR_CTNNB1_TARGETS_DN | MSigDB lists | FEVR_CTNNB1_TARGETS_DN | 523 | 179 | 17377 | 2626 |
H2AFZ,HNRNPAB,THOC1,MOGS,UBQLN2,PAPOLA,KIFC1,PA2G4,PCNA,NUP210,ZNHIT6,DNAAF2,PDS5B,AKR1B1,KIF22,EIF5,CNNM3,DNMT1,SP3,RHOBTB3,RAD51AP1,MKI67,RRM2,CDC6,AURKB,BRCA1,NUTF2,UTP3,SOX4,MCM2,SLC25A5,RFC2,CBFB,LUC7L,DHX15,ASF1B,EIF3A,PRIM1,ANKRD10,CDCA4,NRM,U2SURP,PQBP1,BCL7C,PRPF4,KPNA2,ROCK1,CHEK2,BTF3,RRS1,MRPL13,HDAC2,PFKP,SSRP1,NSMCE4A,KIAA0100,SCOC,CHTF18,NACA,SDC2,RRM1,KIF23,CTCF,RACGAP1,NOTCH2,FAM136A,SPAG5,EIF2S2,SMC3,CCP110,MCM5,MSH2,TIMELESS,KNTC1,GEMIN4,SLC12A2,PABPC1,EEF1D,EIF3L,PRIM2,RB1CC1,GTPBP4,PSMA1,RPS24,DCTD,EIF2A,MATR3,TWISTNB,HAUS8,HMGN2,NAP1L1,DCK,PRPS2,NUP62,YWHAZ,SMPD4,RBBP4,CCNB2,MRPL3,TCF12,ZNF207,SARNP,GNPNAT1,FOXM1,SF3B1,NUF2,STMN1,GLRX3,TCF19,PSMA6,CCNA2,UCHL5,GRSF1,AHCYL1,STRAP,CCT2,RFC3,NXT1,PSMB7,SLBP,NUP155,RAB1A,KDM1B,SHCBP1,GFER,TRIM28,FKBP3,SRSF1,PPP2CA,IDE,HNRNPR,SCARB1,PITRM1,TUBB,RRP15,SRSF6,TRMT6,CDT1,CBLL1,SMC6,ARGLU1,TUBGCP2,FBXO5,SPPL2A,KIF5B,ERH,GART,ADD3,PTEN,PRC1,AXIN2,H2AFY,POLR1B,CREB1,FBL,MSH6,IMPA2,GINS1,HMGN1,ACP2,NASP,HMGN5,KAT2A,ILF3,ADSL,KCNQ1,BORA,RPA1,SLC19A1,KIF18A,MAGT1,RPL32,POLE,BIRC5,E2F1,DDX5,HMGB2,SRSF3,TERF1 |
| 2.568e-28 | -63.53 | BENPORATH_MYC_MAX_TARGETS | MSigDB lists | BENPORATH_MYC_MAX_TARGETS | 737 | 227 | 17377 | 2626 |
UBL3,IER2,COX15,GPR132,H2AFZ,TSC2,NDUFB6,PRKCSH,UQCR10,CXXC1,SNX15,ABCB10,FKBP2,SNRPD3,RBM4,POLR3K,MBD4,PA2G4,RAB8A,PCNA,SRI,HADHB,NUP153,TTC4,CDC25B,ZNRD1,ARID4A,METTL1,USO1,DPM1,GABPA,HARS,RAD51AP1,KIF15,PSMG1,CDC6,PRKRA,STX16,PRPSAP1,RHEB,DPYSL3,RPL37,MKNK1,TMED10,RPS27A,PSMD8,TPP2,PRDX5,WDR4,BAZ1B,CLN3,ARRB2,RPS26,OAZ1,PTOV1,DDX58,UBE2D3,RECQL,LZTR1,MAPRE1,PPP1R12A,PHB2,NACA,UBXN1,CUTA,CIB1,RPL15,ASAH1,THRAP3,RAPGEF6,SPAG5,GNS,SLC31A1,VASP,MLX,RNFT1,MCM5,EFTUD2,CAPZA1,MSH2,MRPL40,ACAD8,ALDH18A1,MAML1,SLC12A2,PPA1,NAGPA,SRSF11,TIMM8B,SIGMAR1,ERLIN1,DCAF8,AMD1,MFNG,PSMA1,SRSF5,STYXL1,EIF4H,ZDHHC3,APPL1,CCT8,ZNF174,PSMC4,RXRB,PTPRF,PCM1,PRPS2,COX7A2L,DCAF11,NUP62,MDH1,MAP3K5,YY1,PTDSS1,TCF12,CYTIP,GLT8D1,PRKAB1,SUCLG1,IVNS1ABP,CHD1L,ACTR3,LAGE3,CREBL2,IRF3,EPM2A,CSDE1,PDK2,PPME1,PPP6C,CLCN6,CDKN1B,AHCYL1,HTRA2,SAP30,CLCN3,NXT1,RPL35,MAPRE2,SEC61B,MKLN1,VDAC2,RNPS1,PSMB7,NDUFB1,RAB1A,AP4E1,SERP1,MAT2A,BTBD1,SUPT16H,DDX17,EIF3K,PPP2CA,DAP3,CDC16,RBL1,TIMM17A,CORO1C,PSMD3,TULP3,RPLP1,FTSJ1,H2AFX,CBWD1,ATF6,USP11,LTA4H,COIL,NDUFS1,SCAMP3,TRMT6,NUP54,ARFIP2,SDF2L1,LANCL1,NCAPG,PMVK,RAB11A,HMG20A,HLA-A,PNO1,FBXO5,MAT2B,NDUFV1,PDCD10,SLC1A4,NDUFA2,CWC27,NDUFB4,H2AFY,RPL19,TAGLN2,POLR1B,PTGES3,CREB1,RBM15B,GINS1,PPP3CA,GALC,PRKDC,LDHA,RPL8,RPL27A,KIF11,TTC33,SNRPA,YIF1A,SERF1B,CACNB1,GNA12,KEAP1,ATP6V1D,RPL32,CCDC6,MFAP1,PARG,DBI,KHSRP,DDX5,PLOD3,IDH3B,YWHAH,IGBP1,DEF6,DDB1,VPS29 |
| 2.778e-28 | -63.45 | mRNA metabolic process | biological process | GO:0016071 | 675 | 214 | 17256 | 2622 |
DDX47,THOC1,PHRF1,RBM8A,ALKBH5,DHX8,USP39,SNRPD3,RBM4,POLR3K,EDC3,PAPOLA,SF3B2,RPL23A,SNUPN,NSRP1,EIF4A3,METTL14,SRSF4,GPATCH1,KHDC4,TRA2B,ECD,ZNRD1,CCAR1,PCBP2,SRPK2,SRSF10,CDC5L,SNRNP200,EXOSC6,SNRPB,HNRNPF,SREK1,DDX20,LUC7L,CLNS1A,DHX15,IWS1,RPL37,PAF1,GEMIN5,RPS27A,RPS14,LUC7L3,U2SURP,PQBP1,PRPF4,RNASEL,SMG9,RPS26,SMNDC1,GEMIN7,DDX42,PRPF38B,RPS15,LIME1,ZCCHC8,POLR2K,GSPT2,DHX9,RPL15,CDK13,THRAP3,PDCD7,PRPF39,CNOT11,PARN,METTL3,CDC73,SRRT,PRPF18,CNOT3,RAVER2,SNRNP25,EXOSC7,CMTR2,EFTUD2,BUD31,ZNF326,YBX1,GEMIN4,CPSF4,PABPC1,LUC7L2,SRSF11,POLR2I,AGGF1,SF3B6,SUGP2,RPL6,RPS10,RPS24,EXOSC9,SRSF5,PATL1,SF3A2,RBM38,RPL36,SYNCRIP,RBM25,POLR2J,RBMX,CEBPG,PRMT7,CNOT6,ZNF830,SNRNP70,TSEN15,SART1,SARNP,RPLP2,CHERP,SF3B1,XAB2,PRKACA,PCBP1,APP,PAIP1,RPL11,HNRNPA2B1,CSDE1,RBM23,ZNF473,GRSF1,EXOSC1,TARDBP,AQR,CHTOP,AHCYL1,RBM15,STRAP,ZC3H3,CDK12,PRPF19,CSTF1,RPL29,RPL35,POLR2G,POLR2L,PPIE,SMU1,CRNKL1,RNPS1,POLR2D,RPL38,SLBP,LSM8,PRPF3,BUD13,TXNL4A,RPS9,RPSA,SRSF1,DDX17,SUGP1,PPP2CA,DHX16,LSM6,HNRNPR,NT5C3B,RPLP1,SNRPG,FUS,PDCD11,PRPF4B,CWC25,CDC40,RPS2,SRSF6,TRMT6,HABP4,AGO2,JMJD6,TUT4,GTF2F1,RBM17,DNAJC8,CTNNBL1,RPL17,CWC27,PPP1R8,PELO,DCP1A,GEMIN6,RPL19,UPF2,CNOT6L,GTF2H2,STAT3,HNRNPM,RBM15B,YTHDC1,SAMD4B,PSPC1,RPL8,TBRG4,PPWD1,DDX39A,RPL27A,SYMPK,SNRPA,POLR2A,DDX23,HSPA1B,CNOT9,UPF1,RPL32,HNRNPH3,KHSRP,ZRANB2,DDX5,SRSF3,HIPK3 |
| 3.427e-28 | -63.24 | KRIGE_RESPONSE_TO_TOSEDOSTAT_24HR_DN | MSigDB lists | KRIGE_RESPONSE_TO_TOSEDOSTAT_24HR_DN | 916 | 265 | 17377 | 2626 |
FGFR1OP,TMEM109,IKBIP,EEF2K,PA2G4,NOL11,THAP4,DNAAF2,TAF5L,PRADC1,SEH1L,AKT2,DCUN1D5,BOLA3,RAD18,LUC7L3,TPP2,WDR4,COX5A,RRS1,HDAC2,HIVEP3,HSPH1,C9orf78,EWSR1,MUM1,ZNRF3,TMED3,FAM136A,CD59,FKBP1A,EXOSC7,SLC38A5,C4orf3,BDH1,GEMIN4,MRPL21,LPCAT1,NAGPA,SRSF11,EIF5A,TIMM8B,DHX29,RDH10,ZNF574,GTPBP4,MFNG,ITM2A,MRPL16,ADRB2,TOMM40,MATR3,TWISTNB,CYB5A,AKAP1,FAS,HSPBP1,CCDC86,DUSP3,PIAS2,TCOF1,YY1,CABLES1,ANKRD27,TMEM97,KLHL18,PRKACA,CD320,UTP18,GRSF1,DUT,TNPO2,FAM76B,GPD1L,CLN6,ARL5A,SAP30,FAM118B,IDH3A,POLR2D,DNAJA1,TMEM147,ASB13,GAR1,DHX57,PEX5,TBL3,FTSJ1,NCLN,BEND3,PDCD11,COIL,PKP4,B4GALT5,MRI1,TCF3,SLC25A12,SDF2L1,SPR,PMVK,PNO1,EBP,GOLM1,AHSA1,FJX1,GEMIN6,COPS7B,TTLL12,GTF2H2,RPL22L1,MSH6,SMC4,NUDC,DDX24,LDHA,ILF3,LLPH,RPL27A,PRDX1,UTP20,INF2,SLC19A1,TFDP1,LRPPRC,SLC25A19,KHSRP,CD81,IPO4,GPATCH4,SSSCA1,BYSL,ESYT2,SRM,UBE2E2,NOP2,MOGS,EBNA1BP2,ABCB10,SLC29A1,CUTC,ZNF696,GOT2,TIMM23,THADA,SIVA1,ATG3,POP7,TRMU,NOC2L,TRIM14,ELOF1,ABCC5,TIMM50,DEAF1,CCDC138,MRPL12,SOX4,LUC7L,ALG3,GEMIN5,TIMM13,NIP7,STK11,RPS26,FUBP1,ASAH1,PM20D2,DNAJB1,LYRM2,SRRT,LYAR,SNRNP25,SSBP3,EI24,MDFIC,ALDH18A1,TRAFD1,DCAF8,AMD1,UTP15,VKORC1,LY6E,SEPT7,ARMC8,GALNT2,UAP1,RBM25,SYNCRIP,PRPS2,SLC16A1,NUP62,RUVBL2,SNRNP70,NAA20,SMARCD1,ZBTB24,USP7,BCCIP,MMACHC,CORO7,GNPNAT1,SLC2A1,UCK2,RPAIN,FARSA,ANKLE1,STRBP,CD3EAP,TARDBP,CLTB,TOP1MT,GM2A,ACSL5,CLPTM1,NXT1,HPDL,NLN,VDAC1,TXNL4A,TMEM201,DUS3L,TIMM17A,GADD45B,NDUFA11,SCARB1,SPRYD4,SMURF1,SLC25A39,PDCD2L,PPP2R2D,CWC25,MIF,RRP15,PDAP1,SRGN,MRPS26,HMGN3,SLC12A9,GGA2,BZW2,HDDC2,TFRC,HOMER1,GART,H2AFY,DDX31,CENPM,POLR1B,LDLRAD3,FBL,ERI3,PPAN,TELO2,NASP,HMGN5,ABCF2,SCFD2,RANGAP1,RHOT2,ARL17A,ZNF330,ACAT1,NR2F2,IDH3B,GCSH |
| 3.634e-28 | -63.18 | GO_RIBONUCLEOPROTEIN_COMPLEX | MSigDB lists | GO_RIBONUCLEOPROTEIN_COMPLEX | 675 | 213 | 17377 | 2626 |
HNRNPAB,MRPS15,RBM8A,DHX8,USP39,EBNA1BP2,SND1,SNRPD3,MRPL19,RBM4,PABPC4,EDC3,SF3B2,KRR1,RPL23A,PA2G4,CDC42,EIF4A3,NSRP1,ZNHIT6,POP7,NOC2L,GPATCH1,FTSJ3,MRPL32,PCBP2,CDC5L,SRP72,SNRNP200,NCK1,SNRPB,NSUN2,MRPL12,MRPL43,HNRNPF,SREK1,BRCA1,UTP3,LUC7L,MAK16,DHX15,RHEB,EIF3A,RPL37,EIF4ENIF1,RPS27A,LUC7L3,RPS14,EIF2D,MRPL27,PQBP1,ATXN2L,ACTB,PRPF4,RRS1,MRPL13,RPS26,SMNDC1,RPS15,PRPF38B,MRPL9,MRPS2,ZCCHC8,DHX9,TIA1,RPL15,EIF2AK4,PRPF39,PDCD7,PRPF18,CNOT3,MCTS1,SNRNP25,EFTUD2,BUD31,ZNF326,YBX1,RBM3,MRPL40,GEMIN4,MRPL48,MVP,MRPL21,PABPC1,NSUN4,LUC7L2,DDX28,EIF3L,DHX29,RPS10,RPL6,PSMA1,RPS24,MRPL16,FXR1,EIF4H,PATL1,SF3A2,ABCF1,RPL36,EPRS,RBM25,SYNCRIP,RBMX,NUP62,RUVBL2,SNRNP70,MRPL3,SART1,RPLP2,IVNS1ABP,SF3B1,XAB2,MRPL39,RAC1,EIF3D,PCBP1,EPM2A,RPL11,MRPL50,HNRNPA2B1,PSMA6,NVL,UTP18,GRSF1,MRPL34,MRPS27,AQR,NAA35,PRPF19,RPL29,RPL35,POLR2G,PPIE,POLR2D,CRNKL1,RPL38,CIRBP,SLBP,NFATC2,PRPF3,NDUFA7,GAR1,TXNL4A,MRPS14,EIF3G,SERP1,RPS9,BTBD1,RPSA,EIF3H,SRSF1,NSA2,SUGP1,EIF3K,MRPL2,DAP3,MRPL55,LSM6,DHX16,HNRNPR,TBL3,ARNTL,RPLP1,SNRPG,FAU,PDCD11,TUBB,PRPF4B,UNK,CDC40,RPS2,MRPL42,MRPS26,JMJD6,SECISBP2,RRP36,JAKMIP1,RBM17,CTNNBL1,RPL17,CWC27,PPP1R8,RRBP1,DCP1A,MRPL54,RPL19,PTGES3,MRPL11,FBL,RPL22L1,HNRNPM,PPAN,STAU1,HELB,RPL8,PARP4,ILF3,MRPS10,PPWD1,RPL27A,DDX39A,API5,SNRPA,DDX23,UTP20,UPF1,RPL32,HNRNPH3,LRPPRC,KHSRP,DDX5,CPEB2 |
| 5.252e-28 | -62.81 | nucleic acid binding | molecular function | GO:0003676 | 4207 | 875 | 17224 | 2647 |
ZBTB10,ADD1,MRPS15,DHX8,LACTB2,RBM4,ZNF275,PABPC4,EEF2K,RPL23A,USF1,NSRP1,THAP4,RAD23B,SRSF4,PDS5B,CRY2,NUP153,ZNRD1,TIPARP,LRRC59,FTSJ3,PCBP2,ZNF672,ERCC1,ZNF559,AATF,GABPA,MRPL43,KIF15,HNRNPF,WDHD1,MIER2,TOPORS,DIDO1,MCM2,AHNAK,SMAD2,RAD18,RPS27A,ZNF689,PRDX5,MYO18A,RNASEL,TFDP2,SMAD1,E2F2,ZNF75A,ANXA11,PDCD4,SMNDC1,DDX42,ZNF720,SSRP1,HIVEP3,MRPL9,CLSPN,DHX9,TOP2B,EIF2AK4,PARN,MCTS1,RAVER2,TFAP4,DDX56,EIF2S2,MCM5,RBM34,EFTUD2,ZNF326,RTCB,FOXN2,MRPL21,CPSF4,PABPC1,NSUN4,LUC7L2,SRSF11,CYFIP1,EIF3L,AGGF1,RBM42,ETV3,FOXK1,PRRC2A,DHX29,ZMYND11,MTA2,SF3B6,GTPBP4,RPS10,MYBL2,USP10,BCLAF1,MRPL16,SRSF5,MPG,ELK1,EIF4H,ABCF1,MATR3,POLR2J,CCDC86,ETS2,TYW5,CNOT6,ZNF830,CFAP20,MRPL3,ZNF207,ZNF296,KARS,SARNP,TRERF1,NQO1,IVNS1ABP,RMI2,MYH9,CREBL2,ZNF267,EFL1,SAFB2,GLRX3,RCOR3,CPNE3,KTN1,APP,RBM23,AHCTF1,ZNF420,SP100,UTP18,ZKSCAN1,MTA1,GRSF1,DUT,GMEB1,ZCCHC2,NABP1,ZNF226,ATF2,RBM15,ZC3H3,CGGBP1,SEC61B,POLR2L,KAT7,CRNKL1,WBP2,RPL38,POLR2D,RNPS1,CIRBP,E2F3,NUSAP1,MEF2D,FKBP3,DDX17,TAF2,LSM6,RBMS1,CENPBD1,FUS,SNRPG,PPP5C,GEN1,ZBTB11,ZNF786,RPS2,ZNF445,SRSF6,ZFP91,TRMT6,HABP4,JMJD6,ETS1,RRP36,PNO1,ZNF92,TUT4,NEIL2,KRI1,RPA2,ZBTB45,ERH,SUV39H2,HUWE1,PPP1R8,PRDM4,ZNF260,ARHGEF1,DCP1A,NAP1L4,ZNF710,FBXL19,GTF2H2,RPL22L1,HNRNPM,STAU1,TNFAIP3,DDX24,POLK,ZNF512,LLPH,DDX39A,RPA1,UTP20,ZNF862,ZNF180,POLE,PITX1,LRPPRC,PML,AEN,HMGB2,WDR76,USF2,THAP5,GPATCH4,DDX47,THOC1,GPBP1L1,YTHDC2,RBM8A,EBNA1BP2,SND1,KCMF1,FANCI,PAPOLA,CREM,KRR1,LIN9,TET3,PCNA,GLIS2,ZNF639,ETV6,TRMU,XRCC2,POP7,NOC2L,EIF5,MYBL1,MTPN,MRPL32,CCAR1,RYBP,SP3,METTL1,RPP25,EXOSC6,BAZ2A,RAD51AP1,SNRPB,ZBED5,MRPL12,EZR,PBRM1,EAF2,UTP3,BRCA1,PRKRA,LUC7L,CHD3,ZNF367,E2F4,PRPF4,KPNA2,ACTB,DHFR2,ZNF45,FAM208A,POT1,CCDC137,ZNF564,FUBP1,CTU2,ZCCHC9,PARP12,HJURP,CTCF,CHCHD2,CDK13,RLF,ASXL2,CRLF3,ARID1B,SUB1,RB1,MLX,MED8,MBD2,SSBP3,XPA,ZNF746,TIMELESS,AHDC1,RBM3,AFF1,ALDH18A1,PREB,NTPCR,LDB1,UTP15,RTF1,ZNF761,EIF4G2,RBM38,IRF5,ZNF174,RXRB,RPL36,PALB2,SYNCRIP,NLRC5,TBPL1,DTD1,RUVBL2,ATP5F1A,TIGD2,BCCIP,SART1,SUCLG1,ARID2,FOXM1,MRPL39,SUMO2,ZNF416,PCBP1,ZNF121,RAD23A,RPL11,CSDE1,ZBTB21,NRF1,PSMA6,ZNF473,MDM2,STRBP,ZNF302,PDCD2,RPAP1,TARDBP,CORO1A,TOP1MT,AHCYL1,STRAP,SAP30L,ZNF583,KDM3B,MND1,RPL29,RPL35,POLR2G,ZNF780B,PPIE,TIGD5,NFATC2,DCLRE1C,PRPF3,KDM1B,MRPS14,EIF3H,RPSA,USP36,SRSF1,SUGP1,MRPL2,DHX16,ZNF700,RBL1,CLK3,MAFK,FASTK,ZNF436,UHRF2,DNAJC17,XRCC3,NCOA1,H3F3A,FAU,LTA4H,SMAD4,RAD51D,ZNF146,NIFK,UNK,MCM10,MIF4GD,CDC40,MTERF1,PDAP1,CDT1,AGO2,ARID5A,GTF3A,HMGN3,NKRF,ARF1,CDK11B,TFRC,WRNIP1,IRF4,DDX31,POLR1B,ORC3,RBM15B,YTHDC1,PPAN,CSRP1,HMGN5,BTAF1,PRKDC,ZNF202,METTL5,ZMYM5,TUFM,TOP3A,RANGAP1,API5,ZFR,DDX23,TPD52L2,SEC23IP,TRIM26,NEIL3,TFE3,BBX,E2F1,IMPDH1,RBPJ,TAF12,NR2F2,IFI16,TXN,ZNF496,MAX,H2AFZ,PNISR,CXXC1,YTHDF3,UBE2I,EIF1B,POLR3K,MYEF2,PARK7,GLMP,UTP25,ZNF428,PA2G4,SNUPN,NOL11,PARPBP,FIZ1,ZNF200,TRA2B,CISD2,SMARCE1,DNMT1,ZNF800,CDC5L,SRSF10,SRP72,NOL12,ZNF524,USO1,KLF10,NOL8,NSUN2,MKI67,DDX20,SLC25A5,RFC2,CBFB,ZFAND5,MAK16,CLNS1A,EIF3A,RCC1L,PRIM1,ZMYM3,DOT1L,HHEX,RBM47,RPS14,LUC7L3,MRPL27,MAP4,EIF2D,BTF3,RRS1,ZNF598,CCDC59,ZMAT3,NMD3,HDAC2,DDX58,PPIB,PRPF38B,RECQL,EWSR1,MAPRE1,POLR2K,CHTF18,GSPT2,PRPF39,ZNF79,ZNF518A,METTL3,RPN1,LHX8,EXOSC7,MEX3C,KLF16,MSH2,MRPL40,TNRC18,ANKHD1,MRM3,EEF1D,TERF2,MORC3,EIF5A,DDX28,ZNF84,PRIM2,NOA1,ZNF574,USF3,C1orf35,RPS24,FAM133B,EXOSC9,PLEC,ARID1A,PKM,CYFIP2,FXR1,KDM3A,PATL1,SF3A2,PHF6,HMGN2,AKAP1,XRCC5,EPRS,ZNF777,ZFP92,RBMX,CEBPG,PIAS2,TCOF1,YY1,ZC3HAV1,CDKN2A,ZNF511,DNMT3A,ZBTB37,SF3B1,CAST,SUZ12,EIF3D,SDE2,PAIP2,TERF2IP,PHC2,CRKL,APLP2,ZNF75D,KDM2A,UCHL5,MRPS27,RNASEH2A,AQR,RBM12B,CDK12,SAP30,CDKN2AIP,RFC3,ERF,HMGN4,DRAP1,SLBP,EDF1,POLG2,H2AFV,GAR1,TRIM28,DHX57,SUPT16H,NSA2,EIF3K,ANKZF1,VEZF1,ZNF282,RAD51C,DGCR8,CERS6,SAFB,TBL3,FAAP100,H2AFX,STAT1,ATF6,TRIM32,BEND3,PDCD11,XRCC4,ATMIN,POLQ,PRPF4B,POU3F2,NCOR2,TWNK,MECP2,TCF3,BRAP,SECISBP2,MYNN,BLM,FOXO3,HMG20A,HLA-A,GTF2F1,JAKMIP1,RBM17,RPL17,MRPL54,RPL19,UPF2,CARF,CREB1,MSH6,NCOA2,TSHZ1,ZFP64,TRIR,ILF3,PARP4,RPL8,RFXANK,TBRG4,BMS1,RPL27A,KLF6,MACF1,MARK2,POLR2A,PRDX1,FBXO21,NUCB1,C1orf131,RPL32,ZHX1,HNRNPH3,MFAP1,TFDP1,KHSRP,DDX5,DUSP11,WDR62,TAF6,CPEB2,PURA,DDB1,BYSL,DDX52,RORB,ZBED3,POLA2,ZNF76,IER2,NOP2,HNRNPAB,UBN1,HMGXB3,FLYWCH2,ALKBH5,ZNF107,KIF2C,TAF6L,AGFG1,SNRPD3,BRIX1,SNAPC4,ZNF696,EDC3,SF3B2,MBD4,ZNF804A,CMSS1,GOT2,EIF4A3,METTL14,JAZF1,PHTF1,HADHB,RPF2,GPATCH1,KHDC4,KIF22,ZBTB22,TCEA1,OGG1,ARID4A,CARM1,TIMM50,SRPK2,FYTTD1,TDP1,DEAF1,SNRNP200,ZCCHC10,SREK1,SOX4,KMT2C,DHX15,RPL37,GEMIN5,UBTF,CXXC4,EIF4ENIF1,NIP7,U2SURP,ATXN2L,PQBP1,IARS2,ZNF268,MRPL13,RPS26,PSMC1,RPS15,ZCCHC8,ZNF768,NACA,TIA1,RPL15,MEF2A,THRAP3,TTF1,SRRT,LYAR,NFATC3,ZNF449,BANF1,ZNF335,BCL2,YBX1,ZNF189,HP1BP3,POLR2I,NUDT4,CIC,SUGP2,RPL6,PSMA1,EIF2A,SLTM,NAP1L1,RBM25,NFIL3,YWHAZ,ZFP90,EHD4,RBBP4,SNRNP70,HNRNPDL,TSEN15,ZBTB24,ADNP2,NOP9,TCF12,MBD1,IMMT,ASH1L,CHERP,MDH2,HNRNPUL2,PMS2,SMARCA4,PLAGL2,IRF3,ORC1,TWF2,CHD1,MXD1,PAIP1,HNRNPA2B1,FARSA,RRN3,ANKLE1,IARS,CD3EAP,NVL,EXOSC1,AKAP8,CS,CHTOP,UTP4,ZNF770,CSTF1,POU2AF1,FAM172A,CGAS,ZNF500,PCGF6,ATXN1,LSM8,BUD13,PEF1,MBD3,EIF3G,RPS9,RAD54B,ZNF317,DAP3,DUS3L,HNRNPR,STAT6,CHCHD1,ARNTL,AKNA,MAPK1,BRD9,CBX4,NAT14,DNAJC2,MRPL42,ZNF316,SHPRH,EYA1,RAE1,SCYL1,MRPS26,DBF4,KLF13,MXD4,GFM2,FASTKD3,PPIG,RRBP1,DUS2,NABP2,H2AFY,BRD7,ANP32A,MRPL11,ERI3,FBL,STAT3,MYO5A,SAMD4B,TELO2,GTF3C6,HEMK1,HMGN1,PSPC1,HELB,MIER1,RCOR1,MEN1,ZNF407,SNRPA,TARS,TFEB,HSPA1B,LEMD2,UPF1,ZC3H7B,KMT2B,ZRANB2,MBD6,SRSF3,CENPT,TERF1 |
| 5.484e-28 | -62.77 | PUJANA_ATM_PCC_NETWORK | MSigDB lists | PUJANA_ATM_PCC_NETWORK | 1363 | 355 | 17377 | 2626 |
MAX,H2AFZ,KDM4A,ADAM10,ABCC10,TAP1,TGOLN2,RPL23A,KIFC1,ANKRD26,CDKN2C,PDS5B,TRA2B,NUP153,TAF5L,ECD,PLCL2,MOB1A,DNMT1,SRSF10,USP34,PGAP2,SRP72,NRAS,AATF,AKT2,MKI67,HNRNPF,AURKB,SMC2,DIDO1,NUTF2,CCNF,MCM2,CBFB,MAK16,WAS,SMAD2,RPS27A,TPP2,PTPN7,OGT,ST3GAL2,BTF3,RRS1,TFDP2,SMNDC1,RECQL,EWSR1,GMFG,RRM1,DHX9,TOP2B,PSMD9,PARN,CNOT3,CFLAR,TFAP4,SMC3,ARPC5,ATIC,MCM5,MSH2,OSTF1,CPSF4,PPP6R1,PABPC1,SRSF11,DDX28,AGGF1,RB1CC1,MYBL2,KCTD20,RPS24,USP10,ARID1A,TOMM40,CBFA2T2,KDM3A,GOSR1,EIF4H,MATR3,CCT8,FAS,HMGN2,SERTAD2,MTHFD2,CSK,DCK,RBMX,PIAS2,TCOF1,YY1,HEXA,RNF139,MRPL3,ZC3HAV1,ATXN3,SF3B1,CAST,SUZ12,URB2,UBR2,RAF1,ACTR3,STARD7,KLHL18,ZNF267,STMN1,CCNA2,SP100,UTP18,DUT,MTA1,ATF2,ADCY7,SAP30,RFC3,HMGN4,CDC123,SLBP,PFKFB3,H2AFV,MAT2A,NSA2,TAF2,RAD51C,HSPA4,ACYP1,LSM6,SAFB,STAT1,FTSJ1,TRIM32,PRPF4B,NCOR2,SRSF6,TCF3,TKT,FAM76A,BTN3A1,SIKE1,BLM,ETS1,PNO1,RPA2,ERH,PDCD10,PTEN,RPL17,AHSA1,ARHGEF1,GTSE1,UPF2,RPL19,CNPY3,GTF2H2,HNRNPM,TMX1,MSH6,SMC4,LDHB,NEK7,ILF3,JTB,LDHA,ADSL,BMS1,DDX39A,RPA1,CBX3,ZNF862,SLC19A1,POLE,PRDX3,TFDP1,LY75,HMGB2,DUSP11,DDX5,IGBP1,ESPL1,DDX52,NPHP4,NOP2,HNRNPAB,UBN1,SNX15,RBM8A,DNAJC24,CSNK2A1,MAP1LC3B,GIT2,FANCI,MBD4,PAPOLA,ZNF804A,FANCL,RAP1A,NUP210,PCNA,EIF4A3,INTS1,XRCC2,ETV6,TCEA1,OGG1,SP3,PTPN18,DPM1,NCK1,BAZ2A,RAD51AP1,SNRPB,VHL,ARHGDIB,UTP3,PITPNB,BRCA1,ODC1,STX16,STK17B,CHAF1A,EPB41,RPL37,HSPB11,E2F4,CRCP,BAZ1B,PRPF4,ACTB,ROCK1,CHEK2,POT1,FUBP1,RMND5A,UBE2D3,PPP1R2,TM9SF4,NACA,CTCF,CDK13,CRLF3,PRPF18,RB1,NFATC3,MBD2,CAPZA1,CTR9,TIMELESS,BCL2,YBX1,RBM3,KNTC1,GLE1,ABCC1,CREG1,RPL6,NFATC2IP,IRF5,NAP1L1,GALNT2,SYNCRIP,SNAP23,NUP62,PITPNA,RBBP4,SMARCD1,ZBTB24,RNF114,KCTD7,IMMT,RPLP2,CHERP,FOXM1,SLC2A1,PLAGL2,CHKB,LYN,PCBP1,RPL11,OIP5,VAV1,HNRNPA2B1,RRN3,MDM2,TNFAIP8,PDCD2,CORO1A,CLTB,ABI1,SCYL3,HTRA2,PRPF19,KDM3B,POU2AF1,DNAJC9,MRPS14,TXNL4A,EIF3H,SRSF1,DAP3,DHX16,HNRNPR,TULP3,STK38,PSMD3,ANP32E,LTA4H,RAD51D,DNAJC2,PDAP1,HMGN3,GTF3A,NKRF,AP3S1,PTPN2,IRF4,CTSS,SLC1A4,PPIG,TANK,ANP32A,ARHGEF2,H2AFY,FBL,GINS1,YTHDC1,TGFB1,TELO2,CSNK1G2,ELOVL5,ADAM17,HMGN1,NASP,SNX2,PRKDC,BTAF1,ABCF2,RCOR1,PPWD1,PCGF1,PRMT2,SNRPA,ZFR,SEC23IP,ZNF330,PKD2,SRSF3,ACADM,IDH3B,CHMP7,UBE2C,HIPK3,IFI16 |
| 8.433e-28 | -62.34 | nuclear body | cellular component | GO:0016604 | 746 | 225 | 18223 | 2701 |
ZNF496,MAX,PNISR,LYRM4,ADD1,THOC1,UBN1,KMT2E,CXXC1,RBM8A,ALKBH5,DHX8,CCNL2,SNRPD3,UBE2I,PPP1R16B,MAPK14,RUFY1,RBM4,PARK7,SF3B2,MBD4,FANCL,PCNA,NEK6,NSRP1,EIF4A3,GLIS2,IMPAD1,SRSF4,KIF22,CRY2,TAF5L,RP2,CARMIL1,OGG1,TIMM50,SRSF10,CDC5L,FYTTD1,SP3,LARS,TRIM8,BAZ2A,EHMT1,MKI67,SREK1,DDX20,TOPORS,USP22,EAF2,LSG1,DHX15,GEMIN5,EIF4ENIF1,BRD2,RAD18,KIF18B,TONSL,LIMK1,LUC7L3,TPP2,EIF2D,ATXN2L,PQBP1,BAZ1B,PRPF4,CHEK2,FBXL3,SMNDC1,GEMIN7,DDX42,NSMCE4A,ZCCHC8,PRKAA1,DHX9,CDK13,THRAP3,METTL3,LMNA,PRPF18,TMEM179B,RB1,INTS7,EFTUD2,CTR9,ICE2,GEMIN4,MAML1,LUC7L2,TERF2,MORC3,HP1BP3,SRSF11,AGGF1,SUGP2,BCLAF1,SRSF5,PATL1,SLTM,SF3A2,DAPK3,FAS,RBM25,PIAS2,ZNF830,SNRNP70,CDK2,USP7,TCF12,MBD1,SART1,TRIM41,SARNP,SF3B1,RAF1,SUZ12,SUMO2,LAGE3,RMI2,POMP,DAZAP2,PRKACA,SAFB2,PCBP1,RPAIN,TERF2IP,HNRNPA2B1,OIP5,SAP130,ZNF473,MDM2,SP100,PIN1,TAP2,TARDBP,FAM76B,CHTOP,RBM15,CDK12,DVL2,RNF169,PRPF19,NXT1,FAM118B,PPIE,SMU1,CRNKL1,RNPS1,POLR2D,ATP6V0A1,ERBIN,PRPF3,NDUFB1,GAR1,TOLLIP,USP36,SRSF1,DDX17,AFDN,KIF2A,DSN1,CLK3,HIPK2,NSMCE2,ARNTL,H2AFX,COIL,CBX4,ATMIN,PRPF4B,CWC25,NCOR2,TRIP12,SRSF6,EYA1,TCF3,CDT1,BABAM1,HABP4,TKT,DBF4,SMC6,CBLL1,BLM,CSNK1A1,RMI1,RFWD3,RPA2,KLHL20,PTEN,PPIG,PPP1R8,GEMIN6,SS18L1,ORC3,FBL,GTF2H2,HNRNPM,NCOA2,SMC4,YTHDC1,TELO2,GTF3C6,POLK,DENND1B,PSPC1,TOP3A,PPWD1,DDX39A,API5,RPA1,HSPA1B,SH3BP5,TATDN2,PML,DUSP11,SRSF3,CENPT,ACADM,ZMIZ1,TERF1,HIPK3,IFI16,S100PBP |
| 1.242e-27 | -61.95 | MORF_AATF | MSigDB lists | MORF_AATF | 200 | 95 | 17377 | 2626 |
IMMT,NUP188,HNRNPAB,PRKCSH,SUMO2,AGPAT1,STARD7,CUL1,GLUD1,UBE2I,SDHA,PABPC4,USP5,RAD23A,TERF2IP,HNRNPA2B1,IARS,PIN1,TXLNA,CS,HADHB,TCEA1,KDM3B,CCT2,SNRNP200,AATF,IDH3A,VDAC2,PSMB7,RNPS1,PKMYT1,ESYT1,MCM2,SERP1,CLNS1A,ALG3,PPP2CA,EIF3K,DAP3,TIMM17A,SAFB,PSMD3,BAZ1B,SCARB1,COPS6,SMNDC1,HDAC2,SSRP1,MRPL9,PHB2,XPO7,SRRT,EBP,TFAP4,RPA2,PSMD2,RPN1,DNAJC8,HUWE1,MCM5,AHSA1,CAPZA1,NAP1L4,CYC1,NUDC,MLEC,POLR2I,KAT2A,PRKDC,WDR18,TUFM,ADSL,BMS1,MTX1,SEPT7,DDX39A,EIF4H,SNRPA,PSMB3,POLR2A,MFN2,XRCC5,EPRS,CSK,ACLY,LRPPRC,NUP62,MDH1,RUVBL2,TCOF1,IDH3B,CDK2,PTDSS1,DDB1,NUDT3 |
| 1.295e-27 | -61.91 | heterocyclic compound binding | molecular function | GO:1901363 | 6080 | 1183 | 17224 | 2647 |
ZBTB10,ABCC10,LACTB2,RBM4,ZNF275,EEF2K,RPL23A,USF1,THAP4,RAD23B,ATP13A3,DNM2,UPRT,CRY2,ZNRD1,TIPARP,LRRC59,FTSJ3,ERCC1,RHOBTB3,ZNF559,NRAS,GABPA,KIF15,HNRNPF,WDHD1,MIER2,DIDO1,MCM2,RAB22A,ARF4,AHNAK,SMAD2,RAD18,RPS27A,MYO18A,RNASEL,SMAD1,ZNF75A,ANXA11,SMNDC1,PDCD4,ZNF720,HIVEP3,CLSPN,RHOC,TRIO,DHX9,RAB23,EIF2AK4,PARN,TFAP4,SMC3,RBM34,EFTUD2,MRPL21,CPSF4,PABPC1,PHKG2,NSUN4,LUC7L2,SRSF11,EIF3L,AGGF1,RBM42,FOXK1,MAPKAPK3,MTA2,SF3B6,TYW1,GTPBP4,USP10,BCLAF1,MRPL16,ELK1,EIF4H,ETS2,TYW5,ZNF830,CFAP20,ACSF2,MRPL3,RHOG,KARS,NQO1,TPX2,GLRX3,RCOR3,CPNE3,CBWD5,RBM23,AHCTF1,ZNF420,MTA1,UBA5,GMEB1,NABP1,CLCN6,SEPT11,ZNF226,GPD1L,ZC3H3,ARL5A,CGGBP1,ULK3,SEC61B,POLR2L,KAT7,IDH3A,CRNKL1,RPL38,CIRBP,E2F3,POLR2D,PFKFB3,MEF2D,RAB1A,MAT2A,KIF2A,LSM6,CENPBD1,SNRPG,PPP5C,TUBB,ZNF445,SRSF6,ZFP91,TRMT6,HABP4,IP6K2,ATP5F1B,PMVK,IFT27,RRP36,NEIL2,TUT4,SRXN1,RPA2,ZBTB45,CBWD2,HUWE1,ARF5,ARHGEF1,ZNF260,NAP1L4,ZNF710,FBXL19,GTF2H2,RPL22L1,STAU1,DDX24,LDHA,LLPH,UTP20,SLC19A1,ACOX1,AEN,THAP5,GPATCH4,YTHDC2,RBM8A,SND1,FANCI,PAPOLA,KRR1,CREM,TET3,RAB8A,GLIS2,POP7,NOC2L,EIF5,MTPN,RYBP,PLK1,RPP25,SEPT9,RAD51AP1,SNRPB,ZBED5,CDC6,PBRM1,EAF2,UTP3,LUC7L,LSG1,CHD3,ZNF367,E2F4,PRPF4,KPNA2,FAM208A,POT1,CCDC137,ZNF564,FUBP1,CTU2,PARP12,ZCCHC9,HJURP,CHCHD2,CDK13,RAB6A,ARID1B,SUB1,MLX,UBE2Q2,MBD2,SSBP3,KIF13B,XPA,ZNF746,AHCY,RBM3,NTPCR,ACSL3,LDB1,MAP4K3,ZNF761,RBM38,IRF5,BBS12,RXRB,RPL36,NLRC5,SIL1,DTD1,RUVBL2,MYO9A,BCCIP,SART1,SUCLG1,ARID2,ZNF416,RRAGC,ATP6V1B2,LYN,PCBP1,ZNF121,NRF1,PSMA6,ZNF473,ZNF302,RPAP1,TARDBP,TOP1MT,AHCYL1,STRAP,ZNF583,KDM3B,MND1,CLCN3,POLR2G,ZNF780B,RAB7A,PPIE,DCLRE1C,MRPS14,EIF3H,SUGP1,IDE,DHX16,RBL1,FASTK,STK38,UHRF2,XRCC3,H3F3A,SMAD4,RAD51D,NADSYN1,NIFK,UNK,MCM10,MTERF1,PDAP1,AGO2,GTF3A,HMGN3,ARF1,CDK11B,SCYL2,GTPBP3,POLR1B,ORC3,RNLS,RBM15B,YTHDC1,PPAN,RHOA,CSRP1,HMGN5,BTAF1,PRKDC,METTL5,ABCF2,TUFM,TOP3A,RANGAP1,PNPLA8,API5,ZFR,DDX23,RAB18,SEC23IP,TRIM26,NEK1,NEIL3,BBX,E2F1,IMPDH1,RBPJ,TAF12,NR2F2,HIPK3,IFI16,TXN,MAX,H2AFZ,PNISR,CXXC1,UBE2I,OAT,MYEF2,PARK7,GLMP,ZNF428,PA2G4,NOL11,FIZ1,RAB4A,ZNF200,TRA2B,SUCLG2,CISD2,SMARCE1,ZNF800,CDC5L,SRSF10,SRP72,ZNF524,KLF10,NSUN2,CBFB,RFC2,RAB2B,CLNS1A,EIF3A,PRIM1,ZMYM3,DOT1L,MAP3K4,HHEX,MKNK1,KIF18B,RPS14,LUC7L3,MRPL27,MAP4,BTF3,CCDC59,ZMAT3,NMD3,PRPF38B,RECQL,EWSR1,POLR2K,PRKAA1,GSPT2,RRM1,CYCS,PRPF39,ZNF79,ZNF518A,PDXDC1,RTKN,RPN1,CEP104,LHX8,EXOSC7,MSH2,DAPK1,MRPL40,CYC1,TNRC18,MRM3,EIF5A,PRIM2,COQ8A,USF3,ZNF574,C1orf35,RPS24,EXOSC9,ARID1A,FXR1,MTR,MAP2K2,CCT8,PHF6,AKAP1,HMGN2,XRCC5,PI4K2A,CAT,HSPBP1,RBMX,PIAS2,CEBPG,CDKN2A,ZNF511,TP53RK,RAB11B,RAF1,KIAA0232,CD320,DECR1,RALB,ADCY9,MRPS27,TAP2,RNASEH2A,AQR,RBM12B,CDK12,SAP30,DRAP1,VDAC2,EDF1,PKMYT1,TRIM28,SUPT16H,EIF3K,ANKZF1,ZNF282,RAD51C,HINT1,RAB24,DGCR8,CERS6,SAFB,CBWD1,ATF6,BEND3,XRCC4,DYNC1LI2,PRPF4B,MECP2,SECISBP2,HMG20A,HLA-A,JAKMIP1,MRPL54,RPL19,CARF,MSH6,RFXANK,BMS1,MACF1,KIF11,KLF6,GUF1,MYO1F,RPL32,ZHX1,DUSP11,DDX5,WDR62,TAF6,PURA,DDB1,RORB,ZBED3,POLA2,ZNF76,HMGXB3,UBE2Q1,ABCB10,BRIX1,ZNF696,SF3B2,CDC42,GOT2,RAB35,JAZF1,HADHB,RPF2,GPATCH1,TCEA1,CARM1,SRPK2,DEAF1,LARS,SNRNP200,ZCCHC10,SREK1,KMT2C,RPL37,EIF4ENIF1,NIP7,U2SURP,CRCP,BAZ1B,ZNF268,STK11,CHEK2,VPS4A,MRPL13,UBE2D3,ZCCHC8,NACA,RPL15,THRAP3,TTF1,CHKA,LYAR,CSNK1G3,POLR2I,NUDT4,SUGP2,RPL6,EIF2A,SLTM,DAPK3,MASTL,NFIL3,YWHAZ,EHD4,SNRNP70,TSEN15,ADNP2,TCF12,MDH2,PMS2,UCK2,SMARCA4,UCK1,ORC1,MXD1,HNRNPA2B1,RRN3,IARS,CD3EAP,NVL,KIF14,EXOSC1,CS,CYB5R1,UTP4,ZNF770,CSTF1,POU2AF1,PCGF6,ATXN1,LSM8,OGDH,MBD3,RPS9,DUS3L,HNRNPR,STAT6,ARNTL,FKBP5,MAPK1,BRD9,ABCA1,NAT14,DNAJC2,ZNF316,SHPRH,RAE1,SCYL1,MYO9B,MXD4,PIP4K2A,GFM2,KIF5B,FASTKD3,FGFR3,GRK2,PPIG,RRBP1,NABP2,DUS2,H2AFY,ANP32A,FBL,ERI3,STAT3,MICAL3,MYO5A,HEMK1,HELB,PSPC1,MIER1,ATP2C1,NADK2,RCOR1,CDK11A,TFEB,LEMD2,UPF1,ZC3H7B,KMT2B,CENPT,HRAS,TERF1,RAB14,ADD1,MRPS15,DHX8,GLUD1,PABPC4,CDK5,NEK6,NSRP1,SRSF4,PDS5B,NUP153,PCBP2,PLK3,ZNF672,AATF,MRPL43,TOPORS,SMC2,ZNF689,LIMK1,PRDX5,TFDP2,E2F2,LONP2,PFKP,SSRP1,DDX42,MRPL9,CERK,TOP2B,RAVER2,MCTS1,DDX56,EIF2S2,MCM5,ZNF326,RTCB,FOXN2,CARS2,UBE2QL1,CYFIP1,ETV3,PRRC2A,DHX29,PGS1,ZMYND11,MYBL2,RPS10,SRSF5,MPG,MATR3,ABCF1,RHOB,CYB5A,CCDC86,POLR2J,CSK,MDH1,CNOT6,ZNF207,ZNF296,SARNP,ABCA3,TRERF1,IVNS1ABP,ACTR3,CHD1L,RMI2,MYH9,CREBL2,EFL1,ZNF267,SAFB2,PRKACA,APP,KTN1,PRKD3,RAB21,SP100,ATP2A2,ZKSCAN1,UTP18,DUT,GRSF1,ZCCHC2,RBM15,ATF2,ADCY7,MAP4K4,RNPS1,WBP2,NUSAP1,DNAJA1,FKBP3,DDX17,TAF2,NT5C3B,HIPK2,RBMS1,FUS,PDXK,ZBTB11,GEN1,ZNF786,GALK1,RPS2,ANXA6,JMJD6,ETS1,ZNF92,PNO1,KRI1,ERH,SUV39H2,GATC,PPP1R8,PRDM4,DCP1A,TTLL12,HNRNPM,LDHB,PDPK1,TK1,GUK1,TNFAIP3,POLK,ZNF512,DDX39A,RPA1,ZNF180,ZNF862,KIF18A,POLE,PITX1,MAPK6,PML,LRPPRC,HMGB2,WDR76,USF2,DDX47,THOC1,GPBP1L1,MCCC1,CSNK2A1,EBNA1BP2,KCMF1,LIN9,ABL2,PCNA,ZNF639,ETV6,TRMU,XRCC2,MYBL1,CCAR1,MRPL32,ABCC5,SP3,METTL1,EXOSC6,BAZ2A,HARS,TLK1,MRPL12,EZR,BRCA1,PRKRA,RAB5B,RHEB,SEPT1,QRSL1,ACTB,DHFR2,ZNF45,SEPHS2,CTCF,RLF,CRLF3,ASXL2,RB1,MED8,TIMELESS,SLC27A4,AFF1,AHDC1,ALDH18A1,PREB,ABCC1,AACS,NQO2,UTP15,RTF1,EIF2AK1,KRAS,UBE4B,EIF4G2,ZNF174,PSMC4,SYNCRIP,PALB2,PRPS2,TBPL1,ATP5F1A,TIGD2,UGP2,FOXM1,MRPL39,SUMO2,RPL11,RAD23A,CSDE1,PDK2,ZBTB21,MDM2,DUS4L,STRBP,PDCD2,CORO1A,SAP30L,RPL29,RPL35,TIGD5,CYP20A1,NFATC2,PRPF3,KDM1B,ARL5B,USP36,RPSA,SRSF1,MRPL2,ATP1A1,CLK3,ZNF700,MAFK,DNAJC17,ZNF436,NCOA1,FAU,LTA4H,ZNF146,CDC40,MIF4GD,CDT1,GNE,ARID5A,ARFIP2,SMC6,NKRF,CSNK1A1,RMI1,TFRC,WRNIP1,STARD9,IRF4,NDUFV1,ABCD1,DDX31,CAMK2G,ZNF202,ZMYM5,RHOT2,TPD52L2,TFE3,PGRMC1,ACADM,RPS6KC1,UBE2C,ZNF496,TAP1,YTHDF3,EIF1B,POLR3K,UTP25,KIFC1,SNUPN,CYB5RL,PARPBP,MAST2,DNMT1,NOL12,USO1,AKT2,PBK,NOL8,MKI67,DDX20,AURKB,SLC25A5,ZFAND5,MAK16,RCC1L,RBM47,EIF2D,DHTKD1,RRS1,ZNF598,HDAC2,DDX58,PPIB,HSPH1,MAPRE1,MUT,CHTF18,KIF23,METTL3,FKBP1A,MEX3C,KLF16,CTPS1,PIKFYVE,GNAI2,ANKHD1,EEF1D,TERF2,MORC3,DDX28,ZNF84,NOA1,PIP4K2C,SEPT8,FAM133B,RIT1,PLEC,CYFIP2,PKM,KDM3A,PATL1,SF3A2,ADSS,EPRS,ZNF777,NSF,ZFP92,QARS,DCK,CSNK1G1,ACLY,TCOF1,MAP3K5,YY1,CDK2,NRBP1,ZC3HAV1,DNMT3A,ZBTB37,CAST,SUZ12,SF3B1,RPS6KA1,EIF3D,RAC1,OLA1,SDE2,SDHA,PAIP2,TERF2IP,PHC2,FLAD1,CRKL,APLP2,ZNF75D,KDM2A,UCHL5,CDKN2AIP,CCT2,RFC3,ATP13A1,HMGN4,ERF,TAOK1,SLBP,GALK2,GAR1,H2AFV,POLG2,DHX57,NSA2,VEZF1,HSPA4,JAK1,GUCY1B1,FAAP100,TBL3,STAT1,H2AFX,TRIM32,PDCD11,ATMIN,CSNK1D,RHEBL1,POLQ,POU3F2,NCOR2,TWNK,TCF3,BRAP,MYNN,BLM,SPR,RAB11A,FOXO3,PIP5K1C,GTF2F1,RBM17,RPL17,UPF2,CREB1,MAP3K14,UBE2M,NCOA2,SMC4,TSHZ1,ZFP64,TRIR,NEK7,RPL8,PARP4,ILF3,TBRG4,RHOT1,RPL27A,MARK2,POLR2A,PRDX1,GNA12,FBXO21,NUCB1,C1orf131,TTLL4,HNRNPH3,MFAP1,TFDP1,KHSRP,NAXE,ASNA1,CPEB2,BYSL,DDX52,IER2,UBE2E2,ST13,NOP2,HNRNPAB,UBN1,FLYWCH2,ALKBH5,ZNF107,UBE2Z,SIRT2,AGFG1,TAF6L,KIF2C,SNRPD3,FKBP2,MAPK14,SNAPC4,EDC3,MBD4,ZNF804A,CMSS1,RAP1A,EIF4A3,METTL14,PHTF1,KHDC4,ZBTB22,KIF22,RP2,OGG1,ARID4A,TIMM50,FYTTD1,TDP1,SOX4,STK17B,DHX15,UBTF,CXXC4,GEMIN5,IARS2,PQBP1,ATXN2L,ROCK1,RPS26,PSMC1,RPS15,ZNF768,TIA1,MEF2A,SRRT,NFATC3,ZNF449,BANF1,ZNF335,YBX1,BCL2,ACAD8,N4BP2,HP1BP3,ZNF189,CIC,PSMA1,SEPT7,GNAS,NAP1L1,RBM25,ZFP90,RBBP4,HNRNPDL,ZBTB24,MBD1,NOP9,MMACHC,IMMT,ASH1L,CHERP,HNRNPUL2,PLAGL2,IRF3,CHKB,TWF2,CHD1,PAIP1,MIEF1,FARSA,ANKLE1,SAR1A,AKAP8,CHTOP,SCYL3,ACSL5,FAM172A,CGAS,ZNF500,BUD13,PEF1,GFER,EIF3G,RAD54B,ZNF317,DAP3,CHCHD1,AKNA,CBX4,KIF3B,MRPL42,EYA1,TOR3A,MRPS26,DBF4,KLF13,GART,BRD7,MRPL11,SAMD4B,TELO2,GTF3C6,CSNK1G2,HMGN1,PRKAR1B,MEN1,ZNF407,SNRPA,TARS,HSPA1B,MFN2,MAPK3,ATAD2,ZRANB2,MBD6,SRSF3,IDH3B,TYW1B |
| 1.561e-27 | -61.72 | MARSON_BOUND_BY_E2F4_UNSTIMULATED | MSigDB lists | MARSON_BOUND_BY_E2F4_UNSTIMULATED | 668 | 210 | 17377 | 2626 |
PIGM,NPHP4,SKA3,H2AFZ,PPP1R15B,TAP1,KIF2C,BRIX1,FANCI,MIS12,FANCL,RAB8A,SIVA1,POP7,XRCC2,TXLNA,TRA2B,JOSD1,KIF22,NUP153,DNMT1,OGG1,SENP1,KCNAB2,TACC3,TIMM50,SRSF10,PLK1,TDP1,RAD51AP1,PBK,NOL8,KIF15,CKAP2L,RRM2,SLC25A22,CDC6,AURKB,SMC2,NUTF2,UTP3,CCNF,ANLN,ASF1B,PRIM1,IWS1,KIF18B,TONSL,ZNF689,ZNF367,MRPL27,NRM,C1orf109,KPNA2,CHEK2,RRS1,SASS6,MRPL13,AAAS,RECQL,MUT,HJURP,CLSPN,FAM53C,CHTF18,ANKH,TATDN3,RRM1,KIF23,RACGAP1,PMF1,SPAG5,LRRC14,DTL,C12orf10,TFAP4,SLC31A1,SMC3,CCP110,INTS7,MCM5,MSH2,MCPH1,NUP85,SRSF11,PRIM2,TYW1,MYBL2,NFATC2IP,ARMC8,MATR3,HAUS8,MASTL,PALB2,DCK,RBMX,CDCA5,CNOT6,SMPD4,EHD4,BTBD10,CCNB2,TSEN15,FAM72A,MMACHC,RAB11B,POC1A,PMS2,TPX2,NUF2,TBC1D13,ORC1,TCF19,USP5,HNRNPA2B1,FLAD1,AHCTF1,CCNA2,SHC1,CD3EAP,NUP107,EFCAB11,INTS12,RPN2,FAM76B,RPRD1B,PRPF19,CSTF1,MND1,NXT1,CRNKL1,DNAJC9,SLBP,NUSAP1,CDCA2,BICD2,GSTCD,SHCBP1,PSMB9,FKBP3,EIF3G,SRSF1,DDOST,RAB24,DGCR8,RBL1,VPS26B,CEP55,STAT1,H2AFX,ANP32E,GEN1,XRCC4,TUBB,POLQ,MCM10,MZT1,DEPDC1,SCAMP3,C1orf112,SRSF6,TCF3,CDT1,CCM2,CDK2AP2,TRMT6,CDCA8,CDCA3,SMC6,MYO9B,BLM,IFT27,FBXO5,RPA2,BTF3L4,PRC1,GEMIN6,GTSE1,CENPM,MSH6,TMX1,SMC4,TXNL1,NASP,ASPM,NET1,PRKDC,SCFD2,TOP3A,CCDC34,RANGAP1,PPWD1,BORA,KIF11,FADD,NEU1,POLR2A,CBX3,PLAA,BIRC5,FAM110A,MFAP1,NEIL3,PML,E2F1,COX8A,WDR76,IDH3B,UBE2C,ESPL1 |
| 1.638e-27 | -61.68 | protein localization | biological process | GO:0008104 | 1943 | 466 | 17256 | 2622 |
CCDC93,TMED7,RAB14,TXN,NUP188,PDCD6IP,TSC2,TAP1,AP3M2,SYNRG,RIC1,PARK7,MIS12,RPL23A,CDK5,NAPG,SNUPN,RABGAP1L,RAB4A,SRSF4,AP1M1,DNM2,AP2B1,NUP153,RNF26,SEH1L,SRP72,PGAP2,USO1,TMEM115,ATG9A,AKT2,NOL8,MRNIP,MCL1,TOPORS,NUTF2,AURKB,ICMT,MCFD2,RAB22A,RAB2B,ARF4,PLEKHF2,HHEX,SMAD2,TMED10,RPS27A,RPS14,EIF2D,VIPAS39,ATP6V0C,BTF3,RRS1,ARRB2,SLF1,NMD3,LONP2,ZMAT3,AAAS,DDX42,NXT2,MAPRE1,GGA1,SEC61G,CUTA,DHX9,RAB23,ACAP1,TMED3,SUPT7L,PSEN1,VPS25,COPG2,LMNA,SPAG5,NPLOC4,COPB2,ATG4A,RTKN,TMEM250,SNX18,FBXO7,TNPO3,ATP6V0A2,PIKFYVE,MVP,CPSF4,SYTL3,NUP85,TMED2,TERF2,MORC3,SRSF11,NAGPA,EIF5A,TIMM8B,GCC2,RPS10,RPS24,SEPT8,SSR2,SRSF5,MTX1,TOMM40,PTTG1IP,GOSR1,RHOB,XRCC5,DERL1,SEC31A,SCARB2,FNTA,KPNA1,NSF,FAM83D,PPP3R1,WIPI2,SGF29,SNX14,NUP58,ALS2,EXOC3,ANKRD27,NDC1,SARNP,ATXN3,SYS1,RAB11B,RAF1,GPR89A,ANK3,VTI1A,C5orf30,MYH9,TBC1D13,AP1B1,STAM,TERF2IP,MOAP1,RAB21,AHCTF1,SP100,TBC1D22A,TBC1D14,NUP107,SEPT11,TNPO2,TAP2,ANKRD13C,ZC3H3,ARL5A,ATP6V1G1,SNX8,SEC61B,GOPC,INTS13,WBP2,RPL38,POLR2D,RNPS1,SLBP,ATP6V0A1,DNAJA1,RAB1A,AP4E1,ERC1,SERP1,PEX5,CHMP4A,HSPA4,SEC61A1,VPS26B,RAB24,CCDC14,CORO1C,RPLP1,SEL1L,PITRM1,CSNK1D,RPS2,MZT1,SCAMP3,SRSF6,MECP2,FLOT1,TRAK1,BTN3A1,SPDL1,IFT27,RAB11A,WRB,HEATR5B,JAKMIP1,RPA2,RPL17,ARF5,AXIN2,DCP1A,RPL19,UPF2,MTX2,PACS2,PPP3CA,TNFAIP3,GUK1,DENND1B,DENND4C,RPL8,RABIF,PACS1,RAB3IP,DDX39A,MACF1,RPL27A,SH3GLB1,RPA1,YIF1A,KIF18A,KEAP1,HGS,RPL32,STX18,PML,SSNA1,CD81,YWHAH,WDR45B,VPS29,FAF1,IPO4,GPR89B,SNAPIN,POLA2,MTX3,AGRN,THOC1,COPA,RBM8A,SNX15,ALKBH5,UBE2Q1,AGFG1,RUFY1,BECN1,SEC16A,SSR1,DLG5,RAB8A,NUP210,RAP1A,TIMM23,EIF4A3,AP3S2,RAB35,ATG3,PIK3R2,SRI,ZFYVE27,RPF2,RP2,CARM1,TIMM50,PTPRK,CDC37,VPS13B,PLK1,FYTTD1,LARS,SEPT9,MIOS,TLK1,EZR,ANLN,STX16,RAB5B,LSG1,OPTN,NECAP2,RPL37,PAF1,TRAM2,SEPT1,TBC1D17,HSPB11,EIF4ENIF1,TIMM13,TONSL,GRIPAP1,UEVLD,TIMM29,MIA2,ARRDC1,KPNA2,CLU,VPS4A,ROCK1,DVL1,RPS26,POT1,ATP6V0E1,C2CD5,TBC1D12,RPS15,GORASP1,PHB2,CENPF,NKD2,LAMTOR3,CTCF,TIA1,RPL15,RAB6A,XPO7,RAPGEF6,RHBDD1,NUP205,RB1,RINL,KIF13B,XPA,PPIL2,ARL6IP1,KIFAP3,YBX1,GLE1,MCPH1,LRSAM1,ATP6V0D1,PREB,KDELR1,RPL6,SYVN1,SEPT7,ZDHHC3,NPIPA1,RPL36,TSC1,GOLGA4,PCM1,SNAP23,LAMTOR4,ODF2,EXOC4,ZDHHC7,SIL1,NUP62,CTSA,RUVBL2,SNX27,CHMP2A,CORO7,TOMM20,RPLP2,TOR1AIP1,COPE,RRAGC,ATP6V1B2,LYN,TWF2,RPAIN,BCAP31,RPL11,HNRNPA2B1,ANKLE1,ATP6V0B,MDM2,SAR1A,KIF14,AKAP8,BCAP29,SCAMP4,LMAN1,CHTOP,AHCYL1,CLTB,DVL2,CHP1,PRPF19,SNX25,RPL29,RPL35,NXT1,PPT1,RAB7A,TOR1AIP2,NUP155,BICD2,ERBIN,CHMP2B,ARL5B,TOLLIP,RPS9,RHBDF2,RPSA,SRSF1,SURF4,VPS26C,TULP3,TOMM6,TIMM17A,CEP55,ARNTL,AP1S1,CHMP4B,SMURF1,AP2S1,TSPAN5,ABCA1,PARD3,TMEM33,CDC40,GOLPH3L,KLHL21,RAE1,SRGN,DCTN2,VPS45,NUP54,ARFIP2,TIMM21,ARF1,GGA2,AP3S1,TFRC,KIF5B,KLHL20,SEC24C,RRBP1,NABP2,H2AFY,ARHGEF2,ATG13,STAT3,CAMK2G,MYO5A,TGFB1,ZDHHC18,NASP,SNX2,SCFD2,COG1,RANGAP1,SYMPK,MFN2,LEMD2,RAB18,SEC23IP,KPNA4,UPF1,ATP6V1D,PDCD6,GOLGA7,OSBPL8,SNAP29,FAM126A,PKD2,RBPJ,SRSF3,SPCS3,CENPT,ATP6V1C1,PLOD3,CHMP7,SLF2,RAB3IL1 |
| 1.798e-27 | -61.58 | Gene Expression | REACTOME pathways | R-HSA-74160 | 1821 | 463 | 10287 | 1696 |
ZNF496,H2AFZ,TXN,NUP188,TSC2,USP39,CCNB1,UBE2I,POLR3K,RPL23A,CDK5,UTP25,PSMD1,SNUPN,NOL11,SRSF4,ZNF200,TRA2B,NUP153,ZNRD1,DNMT1,PCBP2,SEH1L,MLST8,SRSF10,CDC5L,PLK3,SRP72,ZNF559,AKT2,NSUN2,EHMT1,ELOA,HNRNPF,DDX20,AURKB,RFC2,CLNS1A,EIF3A,IWS1,SMAD2,RPS27A,PSMD8,ZNF689,RPS14,PRDX5,WDR4,COX5A,SMG9,TFDP2,ZNF75A,AAAS,SMNDC1,HDAC2,SSRP1,DDX42,ZNF720,COX5B,KRBA1,POLR2K,SEC61G,PRKAA1,GSPT2,DHX9,NDUFA4,CYCS,NOTCH2,PDCD7,ZNF79,PSMD9,PARN,METTL3,CDC73,JMY,CNOT3,RPN1,EIF2S2,EXOSC7,INTS7,EFTUD2,RTCB,MSH2,GEMIN4,CPSF4,MRM3,PABPC1,NUP85,NSUN4,PPA1,EEF1D,CARS2,SRSF11,EIF3L,ELL2,MTA2,TEX10,SF3B6,TYW1,RPS10,PIP4K2C,MYBL2,SSR2,RPS24,EXOSC9,SRSF5,EIF4H,PATL1,SF3A2,PSMB3,TWISTNB,FAS,EPRS,ZNF777,POLR2J,QARS,RBMX,MED15,TYW5,CNOT6,GPI,YY1,CDK2,NUP58,NRBP1,CDKN2A,KARS,NDC1,TP53RK,DNMT3A,SARNP,SF3B1,SUZ12,EIF3D,TPX2,RMI2,ZNF267,C2orf49,ZNF75D,ZNF420,CCNA2,ZKSCAN1,UTP18,MTA1,NUP107,NABP1,INTS12,CDKN1B,ZNF226,AQR,TP53BP2,ATF2,RPRD1B,CDK12,MRM2,SAP30,SEC61B,RFC3,POLR2L,INTS13,RPL38,CRNKL1,RNPS1,POLR2D,SLBP,PSMB9,GAR1,H2AFV,TRIM28,SUPT16H,TAF2,PPP2CA,EIF3K,ZNF282,SEC61A1,DDOST,DGCR8,LSM6,TBL3,HIPK2,NT5C3B,PPA2,RPLP1,FTSJ1,H2AFX,FUS,SNRPG,PDCD11,CSNK1D,ZNF786,NCOR2,RPS2,ZNF445,SRSF6,TRMT6,BLM,RRP36,PNO1,ZNF92,GTF2F1,RBM17,RPA2,CCNK,PSMD2,DNAJC8,PTEN,RPL17,CENPJ,DCP1A,GEMIN6,RPL19,UPF2,CNOT6L,ZNF710,CITED2,GTF2H2,RPL22L1,NCOA2,HNRNPM,PDPK1,KAT2A,WDR18,RPL8,BMS1,RPL27A,DDX39A,PRDX1,POLR2A,RPA1,CBX3,UTP20,ZNF180,RPL32,TFDP1,PML,LRPPRC,KHSRP,DDX5,YWHAH,TAF6,BYSL,DDX52,RORB,CCNC,DDX47,THOC1,NOP2,RBM8A,CSNK2A1,SNRPD3,MAPK14,SNAPC4,FANCI,ZNF696,EDC3,SSR1,PAPOLA,KRR1,SF3B2,TET3,PCNA,NUP210,EIF4A3,INTS1,METTL14,TRMU,POP7,NOC2L,TCEA1,EIF5,MYBL1,CCAR1,CARM1,RPP25,METTL1,FYTTD1,LARS,SNRNP200,EXOSC6,BAZ2A,HARS,SNRPB,BRCA1,EAF2,UTP3,PRKRA,DHX15,RHEB,GEMIN5,RPL37,PAF1,UBTF,CHD3,E2F4,U2SURP,IARS2,PQBP1,BAZ1B,CRCP,STK11,PRPF4,ZNF268,ACTB,CHEK2,ZNF45,PSMC1,RPS26,GEMIN7,ZNF564,UBE2D3,CTU2,RPS15,LAMTOR3,RPL15,COX4I1,CDK13,CNOT11,TTF1,SRRT,NUP205,SNRNP25,TIGAR,MED8,MED10,MBD2,ZNF746,BUD31,CTR9,YBX1,ICE2,MAML1,ZNF189,POLR2I,RPL6,UTP15,PSMA1,RTF1,ZNF761,PSMC4,RPL36,RXRB,TSC1,COX7A2L,LAMTOR4,NUP62,YWHAZ,ZFP90,SNRNP70,RBBP4,TSEN15,USP7,SART1,PRKAB1,RPLP2,CHERP,XAB2,PMS2,LAGE3,ZNF416,RRAGC,PCBP1,PAIP1,MEAF6,RPL11,HNRNPA2B1,SAP130,SEC11A,FARSA,RRN3,MDM2,PSMA6,ZNF473,IARS,BRPF3,ZNF302,CD3EAP,PIN1,EXOSC1,RPN2,CHTOP,ZNF770,UTP4,SAP30L,ZNF583,CSTF1,PRPF19,RPL29,NXT1,RPL35,POLR2G,PSMA8,ZNF500,BTG2,PPIE,PSMB7,LSM8,NUP155,PRPF3,TXNL4A,MBD3,RPS9,EIF3G,RPSA,EIF3H,SRSF1,SUGP1,ZNF317,ZNF700,HNRNPR,RBL1,DHX16,PSMD3,ZNF436,NCOA1,FAU,H3F3A,SMAD4,RAD51D,CWC25,INTS2,CTDP1,CDC40,MTERF1,CASP6,RAE1,AGO2,NUP54,GTF3A,RMI1,PIP4K2A,GTPBP3,CTNNBL1,CWC27,KMT5A,NABP2,DUS2,ANP32A,BRD7,POLR1B,FBL,GTF3C6,RPRD1A,ZNF202,TOP3A,RFFL,POLR3GL,PPWD1,MEN1,SYMPK,SNRPA,TARS,MAPK3,DDX23,CNOT9,UPF1,ATAD2,BIRC5,E2F1,COX8A,TMEM219,RBPJ,TAF12,SPCS3,SRSF3 |
| 2.520e-27 | -61.25 | ribonucleoprotein complex | cellular component | GO:1990904 | 789 | 233 | 18223 | 2701 |
HNRNPAB,MRPS15,RBM8A,DHX8,USP39,EBNA1BP2,SND1,SNRPD3,RBM4,MRPL19,PABPC4,EDC3,SF3B2,RPL23A,KRR1,UTP25,CMSS1,CDC42,NSRP1,EIF4A3,ZNHIT6,POP7,NOC2L,GPATCH1,KHDC4,TRA2B,TAF5L,FTSJ3,MRPL32,MRPL57,CDC5L,SRP72,RPP25,SNRNP200,NCK1,SNRPB,NSUN2,MRPL43,HNRNPF,MRPL12,SREK1,UTP3,LUC7L,MAK16,RHEB,DHX15,EIF3A,RPL37,GEMIN5,EIF4ENIF1,NIP7,RPS27A,RPS14,LUC7L3,MRPL27,EIF2D,ATXN2L,PQBP1,PRPF4,ACTB,ROCK1,RRS1,MRPL13,RPS26,SMNDC1,PRPF38B,RPS15,MRPL9,LIME1,MRPS2,ZCCHC8,DHX9,RPL15,TIA1,TOP2B,EIF2AK4,PDCD7,PRPF39,PRPF18,CNOT3,MCTS1,SNRNP25,EFTUD2,BUD31,ZNF326,YBX1,RBM3,MRPL40,MRPL48,GEMIN4,MRPL21,PABPC1,NSUN4,LUC7L2,DDX28,DHX29,SF3B6,RPL6,RPS10,RPS24,PSMA1,MRPL16,EIF2A,FXR1,EIF4H,PATL1,ABCF1,SF3A2,RPL36,XRCC5,DERL1,EPRS,SYNCRIP,RBM25,RBMX,ZNF830,SNRNP70,MRPL3,SART1,SARNP,RWDD1,RPLP2,IVNS1ABP,MRPL39,SF3B1,XAB2,RAC1,PMS2,PCBP1,RPL11,HNRNPA2B1,MRPL50,PSMA6,NVL,UTP18,GRSF1,MRPL34,MRPS27,AQR,CHTOP,NAA35,PRPF19,RPL29,RPL35,POLR2G,EID1,PPIE,SMU1,CRNKL1,CIRBP,POLR2D,RPL38,SLBP,LSM8,NDUFA7,PRPF3,TXNL4A,GAR1,MRPS14,RPS9,SERP1,BTBD1,RPSA,SRSF1,SUGP1,NSA2,MRPL2,DAP3,MRPL55,DHX16,LSM6,HNRNPR,TBL3,CHCHD1,ARNTL,RPLP1,SNRPG,FUS,PDCD11,TUBB,PRPF4B,UNK,CDC40,RPS2,RRP15,MRPL42,HABP4,AGO2,MRPS26,RRP36,KRI1,RBM17,CTNNBL1,RPL17,CWC27,PPP1R8,RRBP1,DCP1A,MRPL54,LTN1,RPL19,UPF2,PTGES3,MRPL11,FBL,RPL22L1,HNRNPM,PPAN,SAMD4B,STAU1,PARP4,ILF3,RPL8,MRPS10,BMS1,PPWD1,DDX39A,RPL27A,API5,SYMPK,SNRPA,DDX23,HSPA1B,CNOT9,UTP20,UPF1,RPL32,HNRNPH3,KHSRP,DDX5,WDR62,CPEB2,BYSL |
| 2.521e-27 | -61.25 | CDK2 (cyclin dependent kinase 2) | protein interactions | 1017 | 671 | 220 | 17029 | 2761 |
TXN,ST13,COPA,LUZP1,NOP2,KMT2E,CUL1,PTP4A3,SIRT2,CNTROB,SND1,OAT,CCNB1,UBE2I,SEC16A,RBM4,RPL23A,DST,PA2G4,PCNA,EIF4A3,GOT2,DPYSL2,HADHB,CDC25B,DNMT1,ARID4A,PCBP2,CDC37,CDC5L,LARS,KLF10,VHL,HNRNPF,CDC6,BRCA1,ESYT1,MCM2,DHX15,ARF4,EIF3A,CHAF1A,EPB41,DPYSL3,UBTF,RPL37,AHNAK,SMAD2,TMED10,RPS27A,PSMD8,RPS14,E2F4,TPP2,MRPL27,MYO18A,OGT,KPNA2,ACTB,COPS6,MYL12B,C2CD5,FUBP1,PPIB,MAPRE1,PPP1R12A,GORASP1,PHB2,RHOC,DHX9,RRM1,CDK13,CYCS,PSMD9,LMNA,RB1,SUB1,SMC3,CCP110,DAD1,ATIC,CTPS1,MSH2,BCL2,AHCY,RBM3,ALDH18A1,EEF1D,WDR1,ZMYND11,RPS10,RPL6,MYBL2,RPS24,BCLAF1,FAM133B,PLEC,PKM,MATR3,CCT8,DAPK3,HMGN2,XRCC5,RPL36,CAND1,EPRS,NAP1L1,SYNCRIP,TMEM54,GOLGA2,QARS,CEBPG,YWHAZ,CTSA,GPI,TCOF1,ATP5F1A,CDK2,CCNB2,BCCIP,USP7,SARNP,RPLP2,UGP2,FOXM1,RAB11B,MDH2,RAC1,MYH9,ORC1,AP1B1,LYN,PCBP1,STMN1,GNB2,RPL11,RRN3,PSMA6,CCNA2,IARS,PIN1,CDKN1B,TOP1MT,TALDO1,PDIA6,CFL1,CCT2,RPL35,MAPRE2,VDAC2,SLBP,VDAC1,TRIM28,RPS9,EIF3H,SUPT16H,DDX17,PPP2CA,ATP1A1,HSPA4,RBL1,CORO1C,PSMD3,UHRF2,FUS,COIL,MIF,RPS2,CDT1,DBF4,TKT,ARGLU1,ARF1,ATP5F1B,RBM17,PTPN2,CCNK,ERH,PSMD2,CLIC4,PRC1,ANXA5,RPL19,TAGLN2,FBL,UBE2M,S100A6,MYO5A,HNRNPM,SMC4,SPTAN1,LDHB,NASP,KAT2A,PRKDC,TUFM,LDHA,RPL8,ILF3,RPL27A,SNRPA,TARS,PRDX1,POLR2A,RPA1,UPF1,RPL32,BIRC5,PRDX3,MFAP1,TFDP1,PML,LRPPRC,E2F1,GLG1,KHSRP,HMGB2,DDX5,PARP10,YWHAH |
| 2.839e-27 | -61.13 | cellular nitrogen compound biosynthetic process | biological process | GO:0044271 | 3545 | 751 | 17256 | 2622 |
ZBTB10,KDM4A,MRPS15,CCNL2,EDRF1,RBM4,ZNF275,PABPC4,EEF2K,RPL23A,USF1,CIPC,SRSF4,UPRT,CRY2,ECD,ZNRD1,MRPL57,ZNF672,ZNF559,GABPA,MRPL43,MIER2,TOPORS,DIDO1,STOML2,BRMS1,SMAD2,RPS27A,ZNF689,VIPAS39,TFDP2,SMAD1,E2F2,ZNF75A,OAZ1,PFKP,SLC25A33,SSRP1,HIVEP3,MRPL9,MRPS2,DHX9,EZH1,CDC73,MCTS1,TFAP4,EIF2S2,INTS7,EFTUD2,ZNF326,FOXN2,MRPL21,CPSF4,PABPC1,PPA1,CARS2,SRSF11,EIF3L,ETV3,FOXK1,RB1CC1,DHX29,ZMYND11,RPS10,MYBL2,USP10,BCLAF1,MRPL16,SRSF5,CBFA2T2,ELK1,EIF4H,ABCF1,POLR2J,ETS2,SETD3,CNOT6,SGF29,MRPL3,ZNF296,KARS,SARNP,TRERF1,NQO1,IVNS1ABP,PTTG1,RMI2,CREBL2,ZNF267,INO80E,SLC35B2,EFL1,SAFB2,RCOR3,TCF19,ZNF420,SP100,ZKSCAN1,MTA1,DUT,GMEB1,NABP1,INTS12,ZNF226,ATF2,RPRD1B,CGGBP1,PDCL3,ADCY7,CPNE1,POLR2L,EID1,KAT7,INTS13,WBP2,RPL38,POLR2D,RNPS1,E2F3,ATP6V0A1,NDUFA7,MEF2D,DDX17,TAF2,CHCHD3,HIPK2,RPLP1,PDXK,SNRPG,PPP5C,ZBTB11,COMMD10,GALK1,ZNF786,RPS2,ZNF445,SRSF6,HABP4,JMJD6,ATP5F1B,WDR5,ETS1,NEXMIF,ZNF92,NEIL2,RPA2,ZBTB45,ERH,GATC,SUV39H2,PPP1R8,PRDM4,ZNF260,LTN1,ST8SIA2,ZNF710,GTF2H2,RPL22L1,MED22,PDPK1,TK1,GUK1,POLK,ZNF512,LDHA,MRPS10,DDX39A,PDE3B,RPA1,ZNF862,ZNF180,KEAP1,POLE,PITX1,LRPPRC,PML,HMGB2,PARP10,USF2,THAP5,SRM,COX15,THOC1,GPBP1L1,GNPDA1,RBM8A,CSNK2A1,SND1,BIRC2,PAPOLA,CREM,LIN9,PCNA,GLIS2,ZNF639,INTS1,ETV6,XRCC2,NOC2L,PPCDC,EIF5,MYBL1,MRPL32,CCAR1,RYBP,SP3,HARS,BAZ2A,RAD51AP1,SNRPB,MRPL12,PBRM1,EAF2,BRCA1,ODC1,USP21,CHD3,ZNF367,E2F4,QRSL1,DVL1,DHFR2,ZNF45,BEND6,FAM208A,NUDT11,POT1,ZNF564,FUBP1,ZCCHC9,PHB2,CENPF,CTCF,CHCHD2,CDK13,RLF,ASXL2,CNOT11,RSAD1,ARID1B,SUB1,RB1,MLX,MED8,MBD2,SSBP3,ZNF746,CTR9,TIMELESS,MDFIC,ICE2,MRPL48,MAML1,PREB,LDB1,AMD1,UTP15,RTF1,ZNF761,EIF4G2,IRF5,ZNF174,RXRB,RPL36,PALB2,PRPS2,TBPL1,PRMT7,RUVBL2,ATP5F1A,CYLD,TRAF7,RPLP2,UGP2,SUCLG1,ARID2,FOXM1,MRPL39,DYNLL1,XAB2,ZNF416,RRAGC,COMMD8,ZNF121,RPL11,MRPL50,NRF1,ZBTB21,ZNF473,KMT5C,ZNF302,MRPL34,RPAP1,TARDBP,SAP30L,ZNF583,DVL2,KDM3B,RPL29,RPL35,POLR2G,ZNF780B,BTG2,CPOX,NFATC2,KDM1B,MRPS14,EIF3H,RPSA,SRSF1,MRPL2,ZNF700,RBL1,MAFK,ZNF436,DNAJC17,XRCC3,NCOA1,SLC25A39,SMAD4,RAD51D,INTS2,SLC30A9,CTDP1,NADSYN1,NIFK,CDC40,MTERF1,AGO2,ARID5A,GTF3A,NKRF,CHAC2,PAGR1,RMI1,WRNIP1,IRF4,SS18L1,PTGES3,POLR1B,RNLS,RBM15B,RPRD1A,HMGN5,ZNF202,ZMYM5,TUFM,TOP3A,PCGF1,HAGH,BIRC5,L3MBTL3,TFE3,CDCA7L,BBX,E2F1,IMPDH1,RBPJ,TAF12,ACADM,NR2F2,PGAM1,HIPK3,IFI16,TXN,ZNF496,PPCS,MAX,CXXC1,NANS,CCNB1,EIF1B,COMMD6,POLR3K,MYEF2,PA2G4,NOL11,FIZ1,ZNF200,TAF5L,SLC26A2,SPTSSA,DNMT1,ZNF800,CDC5L,ZNF524,KLF10,ELOA,AMDHD2,USP22,CBFB,RFC2,EIF3A,PRIM1,IWS1,HHEX,BRD2,RPS14,MRPL27,EIF2D,DHTKD1,BTF3,ARRB2,ZNF598,CCDC59,HDAC2,PTOV1,COX5B,EWSR1,DHPS,POLR2K,PRKAA1,GSPT2,RRM1,NOTCH2,PMF1,SUPT7L,ZNF518A,ZNF79,VPS25,NPLOC4,CNOT3,YY1AP1,LHX8,KLF16,HDAC7,ATIC,CTPS1,ATP6V0A2,CYC1,MRPL40,EEF1D,TERF2,EIF5A,PHF10,ZNF84,PRIM2,ELL2,NOA1,ZNF574,RPS24,DCTD,ARID1A,PKM,KDM3A,TWISTNB,PHF6,XRCC5,ADSS,EPRS,ZNF777,SERTAD2,ZFP92,RBMX,QARS,DCK,MED15,CEBPG,PIAS2,SAMD8,SMPD4,GPI,YY1,RNF14,NRBP1,NUDT3,ZNF511,ATXN3,RWDD1,ZBTB37,SUZ12,EIF3D,UROD,ADPGK,TERF2IP,SPINDOC,FLAD1,ZNF75D,KDM2A,UCHL5,LPIN2,ADCY9,MRPS27,CDK12,SAP30,BRD4,RFC3,ERF,DRAP1,SLBP,ELP4,EDF1,POLG2,GAR1,TRIM28,CENPU,PRDM11,SUPT16H,EIF3K,VEZF1,RAD51C,ZNF282,MRPL55,HINT1,CERS6,SAFB,GUCY1B1,STAT1,FTSJ1,PPA2,ATF6,BEND3,B4GALT3,EYA2,ATMIN,POLQ,POU3F2,NCOR2,DEPDC1,TWNK,MECP2,TCF3,SECISBP2,MYNN,ARGLU1,BLM,SPR,FOXO3,HMG20A,MAD2L2,WWP2,GTF2F1,CCNK,RPL17,ELP5,MRPL54,RPL19,CARF,CITED2,CREB1,CNOT6L,NCOA2,TSHZ1,ZFP64,KAT2A,ILF3,RPL8,RFXANK,ADSL,RPL27A,KLF6,COMMD4,GUF1,POLR2A,CBX3,RPL32,ATP5MC3,ZHX1,OAZ2,TFDP1,KHSRP,NAXE,DDX5,TAF6,CPEB2,PURA,RORB,CCNC,POLA2,ADA2,ZNF76,IER2,KMT2E,PHRF1,ZNF107,SIRT2,TAF6L,SNRPD3,COMMD5,MAPK14,ATP5PF,SNAPC4,MRPL19,ZNF696,MBD4,EIF4A3,JAZF1,PHTF1,ZBTB22,TCEA1,OGG1,ARID4A,CARM1,ELOF1,LARS,DEAF1,RIOX2,RRM2,SOX4,KMT2C,PRPSAP1,ASF1B,RPL37,GEMIN5,UBTF,PAF1,BRWD1,IARS2,PQBP1,CRCP,BAZ1B,ZNF268,CHEK2,MRPL13,RPS26,RPS15,ZNF768,NACA,MED13L,RPL15,MEF2A,THRAP3,SRRT,TTF1,LYAR,DTL,NFATC3,ZNF449,MED10,ZNF335,BUD31,YBX1,ACAD8,ZNF189,ALDH9A1,VOPP1,ATP5IF1,POLR2I,TSTA3,NUDT4,CIC,RPL6,GBA,EIF2A,SLTM,DAPK3,ISG15,UAP1,NFIL3,NUP62,DNPH1,ZFP90,RBBP4,HNRNPDL,NIPSNAP2,ADNP2,ZBTB24,TCF12,MBD1,MMACHC,ASH1L,MPHOSPH8,GNPNAT1,UCK2,SMARCA4,UCK1,PLAGL2,NSD3,IRF3,CHD1,MXD1,PAIP1,MEAF6,SAP130,FARSA,RRN3,IARS,CD3EAP,AKAP8,CHTOP,UTP4,TMEM14C,ZNF770,RLIM,CSTF1,POU2AF1,CGAS,ZNF500,PCGF6,ATXN1,OGDH,MBD3,EIF3G,RPS9,ZNF317,DAP3,STAT6,CHCHD1,ARNTL,AKNA,MAPK1,BRD9,CBX4,PDF,NAT14,DNAJC2,GCLM,MRPL42,ZNF316,EYA1,SCYL1,MRPS26,KLF13,PAWR,MXD4,GFM2,HDDC2,GART,KMT5A,PELO,RRBP1,NABP2,ANP32A,BRD7,MRPL11,STAT3,AMPD2,TGFB1,SAMD4B,GTF3C6,PSPC1,HELB,MIER1,NADK2,POLR3GL,RCOR1,MEN1,ATP5MF,ZNF407,SYMPK,TARS,MAPK3,TFEB,CNOT9,ATAD2,KMT2B,ACAT1,SRSF3,ZMIZ1,TERF1 |
| 3.451e-27 | -60.93 | GO_MRNA_METABOLIC_PROCESS | MSigDB lists | GO_MRNA_METABOLIC_PROCESS | 569 | 187 | 17377 | 2626 |
DDX47,THOC1,PHRF1,RBM8A,ALKBH5,DHX8,USP39,SNRPD3,RBM4,EDC3,PAPOLA,RPL23A,SF3B2,SNUPN,EIF4A3,NSRP1,METTL14,SRSF4,GPATCH1,TRA2B,CCAR1,PCBP2,SRSF10,SRPK2,CDC5L,SNRNP200,EXOSC6,SNRPB,HNRNPF,SREK1,DDX20,LUC7L,DHX15,CLNS1A,IWS1,GEMIN5,PAF1,RPL37,RPS27A,RPS14,LUC7L3,PQBP1,PRPF4,RNASEL,SMG9,RPS26,SMNDC1,GEMIN7,RPS15,PRPF38B,ZCCHC8,POLR2K,GSPT2,DHX9,RPL15,CDK13,THRAP3,PRPF39,PDCD7,PARN,METTL3,SRRT,CDC73,PRPF18,CNOT3,RAVER2,SNRNP25,EXOSC7,EFTUD2,BUD31,ZNF326,YBX1,GEMIN4,CPSF4,PABPC1,LUC7L2,SRSF11,POLR2I,SUGP2,RPS10,RPL6,RPS24,EXOSC9,SRSF5,PATL1,SF3A2,RBM38,RPL36,SYNCRIP,RBM25,POLR2J,RBMX,CEBPG,PRMT7,CNOT6,SNRNP70,TSEN15,SART1,SARNP,RPLP2,XAB2,SF3B1,PRKACA,PCBP1,APP,PAIP1,RPL11,CSDE1,HNRNPA2B1,RBM23,ZNF473,GRSF1,EXOSC1,TARDBP,AQR,CHTOP,AHCYL1,RBM15,ZC3H3,CDK12,STRAP,PRPF19,CSTF1,RPL29,RPL35,POLR2L,POLR2G,PPIE,POLR2D,RNPS1,CRNKL1,RPL38,SLBP,PRPF3,BUD13,TXNL4A,RPS9,RPSA,SRSF1,PPP2CA,SUGP1,HNRNPR,DHX16,LSM6,RPLP1,SNRPG,FAU,PDCD11,PRPF4B,RPS2,CDC40,SRSF6,JMJD6,GTF2F1,RBM17,DNAJC8,CTNNBL1,CWC27,RPL17,PPP1R8,PELO,DCP1A,GEMIN6,UPF2,RPL19,CNOT6L,GTF2H2,HNRNPM,RBM15B,YTHDC1,PSPC1,HELB,RPL8,PPWD1,RPL27A,DDX39A,SYMPK,SNRPA,POLR2A,DDX23,UPF1,RPL32,HNRNPH3,KHSRP,DDX5,ZRANB2,SRSF3 |
| 3.496e-27 | -60.92 | cellular localization | biological process | GO:0051641 | 2247 | 521 | 17256 | 2622 |
TMED7,RAB14,FGFR1OP,TSC2,TGOLN2,SYNRG,FBXO22,MIS12,RPL23A,CDK5,NAPG,RABGAP1L,SRSF4,AP1M1,DNM2,NUP153,RHOBTB3,TMEM115,TOPORS,PPFIA3,NUTF2,ICMT,RAB22A,ARF4,STOML2,MID1IP1,RPS27A,VIPAS39,LONP2,AAAS,NXT2,GGA1,SEC61G,DHX9,RAB23,HAUS4,TMED3,HAUS2,LMNA,COPB2,ATG4A,CD59,RIMS3,FBXO7,TNPO3,GEMIN4,CPSF4,NUP85,PPP6R1,SRSF11,NAGPA,TIMM8B,ERO1A,RPS10,SSR2,SRSF5,MTX1,RHOB,SCARB2,FNTA,KPNA1,WIPI2,NDE1,SGF29,NUP58,ALS2,EXOC3,ANKRD27,SARNP,ANK3,ACTR3,VTI1A,MYH9,TBC1D13,NUF2,PRKACA,STAM,APP,CLUAP1,RAB21,ATP2A2,SP100,TBC1D22A,TBC1D14,NUP107,SEPT11,ANKRD13C,CEP63,ZC3H3,ARL5A,DCTN1,SNX8,SEC61B,PSRC1,GOPC,INTS13,RPL38,RNPS1,POLR2D,HTATIP2,NUSAP1,DNAJA1,RAB1A,PEX5,SEC61A1,VPS26B,CCDC14,RPLP1,SNRPG,PITRM1,TUBB,RPS2,MZT1,SRSF6,FLOT1,TRAK1,ATP5F1B,IFT27,WRB,SAPCD2,RPA2,PDCD10,DCP1A,GEMIN6,TPCN1,SPTAN1,PPP3CA,TNFAIP3,RAB3IP,DDX39A,PICALM,RPA1,KIF18A,LRPPRC,PML,SSNA1,CD81,YWHAH,WDR45B,SNAPIN,AGRN,THOC1,SNX15,RBM8A,SEC16A,SSR1,RAB8A,NUP210,TIMM23,ZFYVE27,PTPRK,CDC37,PLK1,SEPT9,MIOS,SNRPB,TLK1,EZR,ESYT1,ANLN,STX16,RAB5B,LSG1,OPTN,TRAM2,SEPT1,TBC1D17,TIMM13,GRIPAP1,KPNA2,DVL1,CLN3,POT1,C2CD5,GEMIN7,PHB2,CENPF,NKD2,LAMTOR3,CTCF,RAB6A,RAPGEF6,RB1,CCP110,KIF13B,XPA,PPIL2,ARL6IP1,GLE1,LRSAM1,PREB,TRAPPC9,ZDHHC3,BBS12,RPL36,HAUS8,GOLGA4,PCM1,SNAP23,LAMTOR4,ZDHHC7,SIL1,RUVBL2,ATP5F1A,UNC13C,RPLP2,DYNLL1,TOR1AIP1,COPE,ZFYVE21,RRAGC,LYN,RPAIN,BCAP31,RPL11,MDM2,BCAP29,CORO1A,LMAN1,AHCYL1,DVL2,PRPF19,RPL29,RPL35,PPT1,RAB7A,NUP155,CHMP2B,ARL5B,TMEM201,RPSA,SRSF1,TIMM17A,CEP55,AP1S1,CHMP4B,AP2S1,PARD3,CDC40,KLHL21,CDT1,CDCA8,ARFIP2,GGA2,AP3S1,SCYL2,ABCD1,RBM15B,SNX2,RANGAP1,RHOT2,RAB18,SEC23IP,KPNA4,ATP6V1D,PDCD6,GOLGA7,SNAP29,FAM126A,PKD2,SPCS3,CHMP7,PDCD6IP,NUP188,TXN,AP3M2,TAP1,CCNB1,PARK7,RIC1,KIFC1,SNUPN,RAB4A,AP2B1,TFG,SEH1L,SRSF10,SRP72,USO1,ATG9A,AKT2,NOL8,DDX20,MRNIP,AURKB,MCFD2,RAB2B,HHEX,WAS,TMED10,RPS14,EIF2D,MAP4,RRS1,SLF1,NMD3,COX5B,MAPRE1,DNAJC5,KIF23,SUPT7L,PSEN1,COPG2,VPS25,NPLOC4,SPAG5,RTKN,TMEM250,SNX18,CYC1,PIKFYVE,SYTL3,TMED2,TERF2,MORC3,EIF5A,GCC2,FTL,SEPT8,RPS24,ADRB2,CAPZA2,FXR1,PTTG1IP,TOMM40,GOSR1,XRCC5,SEC31A,DERL1,GOLGA2,NSF,PPP3R1,FAM83D,PPP6R3,NRBP1,NDC1,SYS1,RAB11B,RAF1,RAC1,AP1B1,TERF2IP,MOAP1,TNPO2,TAP2,CUL3,SLBP,CDC23,AP4E1,ERC1,HSPA4,CHMP4A,RAB24,SEL1L,DYNC1LI2,CSNK1D,SPDL1,RAB11A,HEATR5B,PIP5K1C,RPL17,CENPJ,AXIN2,UPF2,RPL19,IFT46,MTX2,PACS2,KAT2A,DENND4C,DENND1B,RPL8,PACS1,RHOT1,RPL27A,MACF1,MARK2,SH3GLB1,YIF1A,HGS,RPL32,ATP5MC3,STX18,WDR91,ESPL1,IPO4,VPS29,ESYT2,POLA2,NPHP4,COPA,MTX3,NF1,ALKBH5,AGFG1,KIF2C,SNRPD3,ATP5PF,BECN1,DST,CDC42,EIF4A3,ATG3,RAB35,AP3S2,SRI,RPF2,KIF22,CARM1,TIMM50,FYTTD1,LARS,TMEM216,GEMIN5,PAF1,RPL37,HSPB11,TIMM29,MIA2,STK11,ROCK1,VPS4A,CLU,RPS26,STARD3NL,RPS15,TBC1D12,GORASP1,RPL15,TIA1,MEF2A,XPO7,RHBDD1,PRPF18,NUP205,BANF1,CAPZA1,YBX1,KIFAP3,MCPH1,KDELR1,RPL6,SYVN1,SEPT7,TSC1,ODF2,CDCA5,EXOC4,NUP62,CTSA,YWHAZ,EHD4,CHMP2A,SNX27,TOMM20,CORO7,CHERP,TWF2,ANKRD28,HNRNPA2B1,ANKLE1,SAR1A,KIF14,PPP6C,CLTB,CHTOP,F2R,CHP1,NXT1,ATXN1,WIPF1,TOR1AIP2,ERBIN,BICD2,TOLLIP,PEF1,RPS9,VPS26C,SURF4,TULP3,ARNTL,ANP32E,SMURF1,TSPAN5,ABCA1,TMEM33,KIF3B,GOLPH3L,RAE1,DCTN2,SRGN,NUP54,VPS45,TIMM21,KIF5B,KLHL20,SEC24C,NABP2,ANP32A,ARHGEF2,H2AFY,YIF1B,ATG13,STAT3,MYO5A,TGFB1,ZDHHC18,ASPM,SCFD2,COG1,WDR81,ATP5MF,SYMPK,MFN2,LEMD2,UPF1,OSBPL8,CENPT,SRSF3,TERF1,SLF2 |
| 5.143e-27 | -60.53 | organic substance biosynthetic process | biological process | GO:1901576 | 4806 | 962 | 17256 | 2622 |
RAB14,ZBTB10,KDM4A,MRPS15,PIGQ,HEXB,AGPAT1,GLUD1,CCNL2,EDRF1,RBM4,ZNF275,PABPC4,EEF2K,RPL23A,USF1,CIPC,SRSF4,MECR,UPRT,CRY2,ECD,ZNRD1,MGAT5,MRPL57,PGAP2,ZNF672,ZNF559,TMEM115,GABPA,MRPL43,WDHD1,MIER2,TOPORS,DIDO1,MCM2,GINS4,STOML2,BRMS1,SMAD2,RPS27A,ZNF689,OGT,MLYCD,VIPAS39,ST3GAL2,TFDP2,SMAD1,E2F2,CHPF2,ZNF75A,OAZ1,PFKP,SLC25A33,SSRP1,HIVEP3,MRPL9,CLSPN,MRPS2,DHX9,EZH1,CDC73,MCTS1,ATG4A,TFAP4,PDXP,EIF2S2,INTS7,MCM5,EFTUD2,ZNF326,FOXN2,MRPL21,CPSF4,PABPC1,PHKG2,PPA1,CARS2,SRSF11,NAGPA,EIF3L,ETV3,FOXK1,RB1CC1,DHX29,ZMYND11,PGS1,MAN1B1,RPS10,MYBL2,USP10,BCLAF1,MRPL16,SRSF5,CBFA2T2,ELK1,EIF4H,ABCF1,POLR2J,ETS2,SETD3,TYW5,MDH1,CNOT6,WIPI2,ZNF830,PLPP6,HEXA,SGF29,MRPL3,ZNF296,KARS,SARNP,TRERF1,IVNS1ABP,PTTG1,STARD7,RMI2,CREBL2,RXYLT1,ZNF267,SLC35B2,INO80E,EFL1,SAFB2,RCOR3,LCLAT1,TCF19,CPNE3,PRKD3,ZNF420,SP100,ZKSCAN1,MTA1,DUT,GMEB1,NABP1,INTS12,ZNF226,ATF2,GPD1L,RPRD1B,CGGBP1,PDCL3,ADCY7,CPNE1,POLR2L,EID1,KAT7,INTS13,WBP2,RPL38,POLR2D,RNPS1,E2F3,ATP6V0A1,NDUFA7,MEF2D,TAZ,MAT2A,DDX17,TAF2,CHCHD3,ALDH3B1,HIPK2,RPLP1,RBMS1,MBOAT1,PDXK,SNRPG,PPP5C,ZBTB11,COMMD10,GALK1,ZNF786,RPS2,ZNF445,SRSF6,HABP4,TRAK1,JMJD6,ATP5F1B,IP6K2,WDR5,ETS1,PMVK,NEXMIF,ZNF92,NEIL2,RPA2,ZBTB45,ERH,GATC,COQ4,SUV39H2,PPP1R8,PRDM4,ZNF260,LTN1,ST8SIA2,ZNF710,GTF2H2,RPL22L1,MED22,IMPA2,PDPK1,TK1,GUK1,POLK,ZNF512,LDHA,MRPS10,MTMR12,DDX39A,PDE3B,RPA1,ZNF180,ZNF862,KEAP1,MAGT1,POLE,PITX1,DBI,LRPPRC,PML,HMGB2,PARP10,USF2,WDR45B,THAP5,SRM,COX15,AGRN,THOC1,GPBP1L1,GNPDA1,RBM8A,CSNK2A1,SND1,CDIPT,RUFY1,BIRC2,PAPOLA,CREM,LIN9,TET3,PCNA,GLIS2,ZNF639,INTS1,ETV6,PIK3R2,SLC44A1,XRCC2,NOC2L,PPCDC,EIF5,MCMBP,MYBL1,MRPL32,CCAR1,ABCC5,RYBP,SP3,HARS,BAZ2A,RAD51AP1,SNRPB,MRPL12,CDC6,PBRM1,EAF2,BRCA1,KRTCAP2,ODC1,USP21,ALG3,AGPAT2,TONSL,CHD3,ZNF367,E2F4,QRSL1,DVL1,DHFR2,ZNF45,BEND6,FAM208A,NUDT11,POT1,ZNF564,FUBP1,SEPHS2,ZCCHC9,PHB2,CENPF,SDC2,CTCF,CHCHD2,CDK13,B4GALT4,RLF,ASXL2,CNOT11,RSAD1,ARID1B,C1GALT1,SUB1,RB1,MLX,NUS1,MED8,MBD2,SSBP3,ZNF746,CTR9,TIMELESS,MDFIC,AHCY,ICE2,MRPL48,MAML1,ALDH18A1,PREB,ABHD2,AACS,NSDHL,ACSL3,LDB1,AMD1,UTP15,RTF1,ZNF761,LY6E,EIF4G2,ZDHHC3,NMT2,IRF5,ZNF174,RXRB,RPL36,MBIP,GALNT2,PALB2,PRPS2,TBPL1,ZDHHC7,PRMT7,DTD1,RUVBL2,ATP5F1A,GLT8D1,CYLD,TRAF7,RPLP2,UGP2,SUCLG1,ARID2,FOXM1,MRPL39,DYNLL1,XAB2,SLC2A1,ZNF416,RRAGC,GGPS1,COMMD8,RPAIN,ZNF121,RPL11,MRPL50,ZBTB21,NRF1,ZNF473,KMT5C,ZNF302,MRPL34,RPAP1,TARDBP,LMAN1,TOP1MT,SAP30L,ZNF583,DVL2,PRPF19,KDM3B,RPL29,RPL35,POLR2G,ZNF780B,PPT1,COQ10B,BTG2,CPOX,MTMR6,NFATC2,KDM1B,MRPS14,EIF3H,RPSA,SRSF1,MRPL2,ZNF700,RBL1,MAFK,ZNF436,DNAJC17,XRCC3,NCOA1,LTA4H,SLC25A39,SMAD4,RAD51D,INTS2,SLC30A9,CTDP1,NADSYN1,NIFK,MCM10,CDC40,MTERF1,CDT1,GNE,AGO2,ARID5A,GTF3A,NKRF,ARF1,CHAC2,PAGR1,RMI1,WRNIP1,GSTK1,IRF4,SS18L1,PTGES3,POLR1B,ORC3,RNLS,RBM15B,CNTN5,RPRD1A,HMGN5,ZNF202,ZMYM5,TUFM,TOP3A,PNPLA8,PCGF1,HAGH,GOLGA7,BIRC5,L3MBTL3,TFE3,CDCA7L,BBX,E2F1,IMPDH1,RBPJ,TAF12,ACADM,NR2F2,PGAM1,HIPK3,IFI16,TXN,ZNF496,MAX,PPCS,GXYLT1,ZDHHC8,CXXC1,NANS,GYG1,CCNB1,OAT,EIF1B,COMMD6,POLR3K,MYEF2,PARK7,PA2G4,NOL11,FIZ1,RAB4A,ZNF200,TAF5L,SLC26A2,SPTSSA,DNMT1,ZNF800,CDC5L,ZNF524,KLF10,AKT2,ELOA,USP22,GALNT7,AMDHD2,MCFD2,CBFB,RFC2,EIF3A,PRIM1,IWS1,HHEX,BRD2,STT3A,RPS14,MRPL27,EIF2D,DHTKD1,BTF3,ARRB2,ZNF598,CCDC59,HDAC2,B4GALT2,PTOV1,COX5B,EWSR1,DHPS,POLR2K,CHTF18,PRKAA1,GSPT2,RRM1,B4GALT1,PMF1,NOTCH2,SUPT7L,ZNF79,ZNF518A,PSEN1,TMEM165,VPS25,YY1AP1,NPLOC4,CNOT3,RPN1,LHX8,KLF16,HDAC7,ATIC,DAD1,BDH1,CTPS1,PIGG,ATP6V0A2,MRPL40,CYC1,PCYT2,PIKFYVE,LPCAT1,EEF1D,TERF2,FDFT1,EIF5A,PHF10,ZNF84,PIGT,PRIM2,ELL2,COQ8A,NOA1,RDH10,MFNG,PIP4K2C,ZNF574,RPS24,DCTD,ARID1A,PKM,KDM3A,MTR,TWISTNB,PHF6,XRCC5,PI4K2A,ADSS,EPRS,ZNF777,SERTAD2,GOLGA2,ZFP92,RBMX,QARS,DCK,MED15,ACLY,PIAS2,CEBPG,LPCAT4,SAMD8,SMPD4,GPI,YY1,RNF14,CDK2,NRBP1,NUDT3,ZNF511,ATXN3,RWDD1,ZBTB37,SUZ12,EIF3D,UROD,ADPGK,SDE2,TERF2IP,SPINDOC,FLAD1,ZNF75D,KDM2A,MTMR4,UCHL5,LPIN2,ADCY9,MRPS27,RNASEH2A,TALDO1,CDK12,SAP30,BRD4,RFC3,ERF,DRAP1,SLBP,ELP4,EDF1,POLG2,GAR1,SERP1,TRIM28,CENPU,PRDM11,SUPT16H,EIF3K,VEZF1,ZNF282,RAD51C,MRPL55,DDOST,HINT1,CERS6,SAFB,GUCY1B1,STAT1,FTSJ1,PPA2,ATF6,BEND3,B4GALT3,EYA2,ATMIN,POLQ,POU3F2,NCOR2,DEPDC1,B4GALT5,TWNK,MECP2,MRI1,TCF3,TKT,SLC25A12,AGPAT3,ARGLU1,SECISBP2,MYNN,SDF2L1,BLM,SPR,POFUT1,HMG20A,FOXO3,MAD2L2,PIP5K1C,WWP2,GTF2F1,EBP,RFWD3,MAT2B,CCNK,RPL17,ELP5,PTEN,FUT8,PTPN11,MRPL54,RPL19,CARF,CITED2,CNOT6L,CREB1,OSTC,NCOA2,TSHZ1,ZFP64,KAT2A,WDR18,ILF3,RPL8,RFXANK,ADSL,RPL27A,COMMD4,KLF6,GUF1,POLR2A,CBX3,RPL32,ATP5MC3,ZHX1,TFDP1,OAZ2,NAXE,KHSRP,DDX5,TAF6,CPEB2,PURA,RORB,ADA2,POLA2,CCNC,ZNF76,PTMS,PIGM,IER2,KMT2E,PHRF1,MOGS,ZNF107,TAF6L,SIRT2,SNRPD3,COMMD5,MAPK14,ATP5PF,SNAPC4,MRPL19,ZNF696,BCAT2,MBD4,GOT2,EIF4A3,IMPAD1,JAZF1,PHTF1,AKR1B1,ZBTB22,TCEA1,SLC35C2,TECR,OGG1,ARID4A,CARM1,ELOF1,DEAF1,LARS,DPM1,RIOX2,RRM2,KMT2C,SOX4,PRPSAP1,MPC1,ASF1B,CHAF1A,ABHD5,RPL37,PAF1,GEMIN5,MAN2A2,UBTF,BRWD1,PQBP1,IARS2,CRCP,BAZ1B,ZNF268,CHEK2,GALNT10,CHPT1,MRPL13,RPS26,STARD3NL,RPS15,PIGN,GORASP1,ZNF768,NACA,MED13L,RPL15,MEF2A,THRAP3,TTF1,SRRT,CHKA,LYAR,DTL,NFATC3,ZNF449,MED10,PYURF,BUD31,ZNF335,YBX1,ACAD8,ZNF189,ALDH9A1,VOPP1,ATP5IF1,POLR2I,TSTA3,NUDT4,CIC,RPL6,GBA,EIF2A,SYVN1,SLTM,DAPK3,ISG15,NAP1L1,UAP1,NFIL3,NUP62,DNPH1,ZFP90,RBBP4,NANP,HNRNPDL,NIPSNAP2,PTDSS1,PDSS2,ZBTB24,ADNP2,TCF12,MBD1,PRKAB1,MMACHC,ASH1L,MPHOSPH8,GNPNAT1,MDH2,UCK2,SMARCA4,UCK1,PLAGL2,NSD3,CHKB,ORC1,IRF3,CHD1,EXT2,MEAF6,MXD1,PAIP1,SAP130,FARSA,RRN3,IARS,CD3EAP,AKAP8,RPN2,CYB5R1,CHTOP,UTP4,ZNF770,TMEM14C,RLIM,CSTF1,POU2AF1,ACSL5,CGAS,ZNF500,PCGF6,ATXN1,OGDH,MBD3,EIF3G,RPS9,PDHX,ZNF317,DAP3,STAT6,CHCHD1,ARNTL,CANT1,SCARB1,AKNA,MAPK1,BRD9,ABCA1,CBX4,PDF,NAT14,MIF,DNAJC2,GCLM,CDS2,MRPL42,ZNF316,EYA1,SCYL1,MRPS26,DBF4,KLF13,PAWR,MXD4,PIP4K2A,GFM2,HDDC2,MAN1A1,FGFR3,GART,KMT5A,PELO,RRBP1,NABP2,BRD7,ANP32A,MRPL11,STAT3,MYO5A,SLC25A1,AMPD2,TGFB1,SAMD4B,B3GALT6,GINS1,ELOVL5,ZDHHC18,CSNK1G2,GTF3C6,NASP,PSPC1,HELB,MIER1,NADK2,RCOR1,POLR3GL,MEN1,ATP5MF,ZNF407,SYMPK,TARS,MAPK3,TFEB,CNOT9,MTMR3,UPF1,ATAD2,KMT2B,ACAT1,SRSF3,ZMIZ1,PLOD3,TERF1 |
| 5.542e-27 | -60.46 | cellular response to DNA damage stimulus | biological process | GO:0006974 | 748 | 227 | 17256 | 2622 |
UBE2E2,TMEM109,XIAP,ALKBH5,CCNB1,UBE2I,MAPK14,PARK7,FANCI,MBD4,FANCL,PCNA,CYREN,PARPBP,XRCC2,RAD23B,PDS5B,KIF22,FNIP2,CRY2,TCEA1,OGG1,CARM1,CDC5L,PLK3,PLK1,COPS8,BAK1,PGAP2,TDP1,ERCC1,AATF,RBX1,RAD51AP1,TLK1,MRNIP,WDHD1,TOPORS,MCL1,UBE2V1,BRCA1,SOX4,RFC2,GINS4,CHAF1A,DOT1L,RAD18,TONSL,RPS27A,E2F4,BAZ1B,STK11,CHEK2,TFDP2,COPS6,SLF1,ZMAT3,SSRP1,UBE2D3,RECQL,NSMCE4A,CLSPN,POLR2K,MUM1,CDIP1,CIB1,EIF2AK4,CNOT11,PSEN1,METTL3,PITHD1,WDR48,NPLOC4,CNOT3,JMY,MCTS1,DTL,TFAP4,SMC3,TIGAR,INTS7,XPA,MSH2,TIMELESS,BCL2,TERF2,POLR2I,USP10,ARMT1,MPG,ISG15,XRCC5,MASTL,PAXX,PALB2,POLR2J,CDCA5,CNOT6,RUVBL2,YY1,ZNF830,CDK2,BCCIP,USP7,ATXN3,FOXM1,XAB2,SUMO2,PTTG1,CHD1L,PMS2,RMI2,IRF3,BCL2L1,INO80E,LYN,RPAIN,RAD23A,MOAP1,TERF2IP,ANKLE1,BABAM2,MDM2,KDM2A,SP100,UCHL5,MTA1,NABP1,CDKN1B,RNASEH2A,AQR,CEP63,ATF2,SPIDR,HTRA2,RNF169,PRPF19,MND1,CDKN2AIP,RFC3,BRD4,POLR2L,POLR2G,CGAS,BTG2,TAOK1,PPIE,POLR2D,NFATC2,DCLRE1C,DNAJA1,POLG2,FANCE,TRIM28,RAD54B,SUPT16H,RAD51C,NSMCE2,HIPK2,FAAP100,H2AFX,XRCC3,PPP5C,MAPK1,GEN1,XRCC4,EYA2,RAD51D,ATMIN,POLQ,SLC30A9,MIF,MCM10,TRIP12,EYA1,SHPRH,BABAM1,MRPS26,SMC6,BLM,PAGR1,FOXO3,RMI1,MAD2L2,NEIL2,NEXMIF,WRNIP1,CCNK,RPA2,RFWD3,RBM17,HUWE1,CENPJ,TANK,NABP2,PTPN11,GTSE1,COPS7B,CNOT6L,GTF2H2,MSH6,HMGN1,POLK,HELB,PRKDC,PARP4,TOP3A,MEN1,DDX39A,CHCHD6,POLR2A,RPA1,MAPK3,CNOT9,UPF1,NEK1,POLE,NEIL3,TFDP1,E2F1,PML,AEN,HMGB2,WDR76,SLF2,DDB1,IFI16 |
| 6.446e-27 | -60.31 | cellular biosynthetic process | biological process | GO:0044249 | 4724 | 948 | 17256 | 2622 |
RAB14,ZBTB10,KDM4A,MRPS15,PIGQ,HEXB,AGPAT1,GLUD1,CCNL2,EDRF1,RBM4,ZNF275,PABPC4,EEF2K,RPL23A,USF1,CIPC,SRSF4,MECR,UPRT,CRY2,ECD,ZNRD1,MGAT5,MRPL57,PGAP2,ZNF672,ZNF559,TMEM115,GABPA,MRPL43,WDHD1,MIER2,TOPORS,DIDO1,MCM2,GINS4,STOML2,BRMS1,SMAD2,RPS27A,ZNF689,OGT,MLYCD,VIPAS39,ST3GAL2,TFDP2,SMAD1,E2F2,CHPF2,ZNF75A,OAZ1,PFKP,SLC25A33,SSRP1,HIVEP3,MRPL9,CLSPN,MRPS2,DHX9,EZH1,CDC73,MCTS1,ATG4A,TFAP4,PDXP,EIF2S2,INTS7,MCM5,EFTUD2,ZNF326,FOXN2,MRPL21,CPSF4,PABPC1,PHKG2,PPA1,CARS2,SRSF11,NAGPA,EIF3L,ETV3,FOXK1,RB1CC1,DHX29,ZMYND11,PGS1,MAN1B1,RPS10,MYBL2,USP10,BCLAF1,MRPL16,SRSF5,CBFA2T2,ELK1,EIF4H,ABCF1,POLR2J,ETS2,SETD3,CNOT6,WIPI2,ZNF830,SGF29,MRPL3,ZNF296,KARS,SARNP,TRERF1,NQO1,IVNS1ABP,PTTG1,STARD7,RMI2,CREBL2,RXYLT1,ZNF267,SLC35B2,INO80E,EFL1,SAFB2,RCOR3,LCLAT1,TCF19,CPNE3,PRKD3,ZNF420,SP100,ZKSCAN1,MTA1,DUT,GMEB1,NABP1,INTS12,ZNF226,ATF2,GPD1L,RPRD1B,CGGBP1,PDCL3,ADCY7,CPNE1,POLR2L,EID1,KAT7,INTS13,WBP2,RPL38,POLR2D,RNPS1,E2F3,ATP6V0A1,NDUFA7,MEF2D,TAZ,MAT2A,DDX17,TAF2,CHCHD3,ALDH3B1,HIPK2,RPLP1,RBMS1,MBOAT1,PDXK,SNRPG,PPP5C,ZBTB11,COMMD10,GALK1,ZNF786,RPS2,ZNF445,SRSF6,HABP4,TRAK1,JMJD6,ATP5F1B,WDR5,ETS1,PMVK,NEXMIF,ZNF92,NEIL2,RPA2,ZBTB45,ERH,GATC,COQ4,SUV39H2,PPP1R8,PRDM4,ZNF260,LTN1,ST8SIA2,ZNF710,GTF2H2,RPL22L1,MED22,IMPA2,PDPK1,TK1,GUK1,POLK,ZNF512,LDHA,MRPS10,MTMR12,DDX39A,PDE3B,RPA1,ZNF862,ZNF180,KEAP1,MAGT1,POLE,PITX1,DBI,LRPPRC,PML,HMGB2,PARP10,USF2,WDR45B,THAP5,SRM,COX15,THOC1,GPBP1L1,GNPDA1,RBM8A,CSNK2A1,SND1,CDIPT,RUFY1,BIRC2,PAPOLA,CREM,LIN9,TET3,PCNA,GLIS2,ZNF639,INTS1,ETV6,PIK3R2,SLC44A1,XRCC2,NOC2L,PPCDC,EIF5,MCMBP,MYBL1,MRPL32,CCAR1,ABCC5,RYBP,SP3,HARS,BAZ2A,RAD51AP1,SNRPB,MRPL12,CDC6,PBRM1,EAF2,BRCA1,KRTCAP2,ODC1,USP21,ALG3,AGPAT2,TONSL,CHD3,ZNF367,E2F4,QRSL1,DVL1,DHFR2,ZNF45,BEND6,FAM208A,NUDT11,POT1,ZNF564,FUBP1,SEPHS2,ZCCHC9,PHB2,CENPF,CTCF,CHCHD2,CDK13,B4GALT4,RLF,ASXL2,CNOT11,RSAD1,ARID1B,C1GALT1,SUB1,RB1,MLX,NUS1,MED8,MBD2,SSBP3,ZNF746,CTR9,TIMELESS,MDFIC,AHCY,ICE2,MRPL48,MAML1,ALDH18A1,PREB,ABHD2,AACS,ACSL3,LDB1,AMD1,UTP15,RTF1,ZNF761,LY6E,EIF4G2,ZDHHC3,NMT2,IRF5,ZNF174,RXRB,RPL36,MBIP,GALNT2,PALB2,PRPS2,TBPL1,ZDHHC7,PRMT7,DTD1,RUVBL2,ATP5F1A,CYLD,TRAF7,RPLP2,UGP2,SUCLG1,ARID2,FOXM1,MRPL39,DYNLL1,XAB2,SLC2A1,ZNF416,RRAGC,GGPS1,COMMD8,RPAIN,ZNF121,RPL11,MRPL50,ZBTB21,NRF1,ZNF473,KMT5C,ZNF302,MRPL34,RPAP1,TARDBP,LMAN1,TOP1MT,SAP30L,ZNF583,DVL2,KDM3B,RPL29,RPL35,POLR2G,ZNF780B,PPT1,COQ10B,BTG2,CPOX,MTMR6,NFATC2,KDM1B,MRPS14,EIF3H,RPSA,SRSF1,MRPL2,ZNF700,RBL1,MAFK,ZNF436,DNAJC17,XRCC3,NCOA1,LTA4H,SLC25A39,SMAD4,RAD51D,INTS2,SLC30A9,CTDP1,NADSYN1,NIFK,MCM10,CDC40,MTERF1,CDT1,AGO2,ARID5A,GTF3A,NKRF,ARF1,CHAC2,PAGR1,RMI1,WRNIP1,GSTK1,IRF4,SS18L1,PTGES3,POLR1B,ORC3,RNLS,RBM15B,CNTN5,RPRD1A,HMGN5,ZNF202,ZMYM5,TUFM,TOP3A,PNPLA8,PCGF1,HAGH,GOLGA7,BIRC5,L3MBTL3,TFE3,CDCA7L,BBX,E2F1,IMPDH1,RBPJ,TAF12,ACADM,NR2F2,PGAM1,HIPK3,IFI16,TXN,ZNF496,MAX,PPCS,GXYLT1,ZDHHC8,CXXC1,NANS,GYG1,CCNB1,OAT,EIF1B,COMMD6,POLR3K,MYEF2,PARK7,PA2G4,NOL11,FIZ1,RAB4A,ZNF200,TAF5L,SLC26A2,SPTSSA,DNMT1,ZNF800,CDC5L,ZNF524,KLF10,AKT2,ELOA,GALNT7,AMDHD2,USP22,MCFD2,CBFB,RFC2,EIF3A,PRIM1,IWS1,HHEX,BRD2,STT3A,RPS14,MRPL27,EIF2D,DHTKD1,BTF3,ARRB2,ZNF598,CCDC59,HDAC2,B4GALT2,PTOV1,COX5B,EWSR1,DHPS,POLR2K,CHTF18,PRKAA1,GSPT2,RRM1,B4GALT1,PMF1,NOTCH2,SUPT7L,ZNF79,ZNF518A,PSEN1,TMEM165,VPS25,YY1AP1,CNOT3,NPLOC4,RPN1,LHX8,KLF16,HDAC7,ATIC,DAD1,BDH1,CTPS1,PIGG,ATP6V0A2,MRPL40,CYC1,PCYT2,PIKFYVE,LPCAT1,EEF1D,TERF2,FDFT1,EIF5A,PHF10,ZNF84,PIGT,PRIM2,ELL2,COQ8A,NOA1,RDH10,MFNG,PIP4K2C,ZNF574,RPS24,DCTD,ARID1A,PKM,KDM3A,MTR,TWISTNB,PHF6,XRCC5,PI4K2A,ADSS,EPRS,ZNF777,SERTAD2,GOLGA2,ZFP92,RBMX,QARS,DCK,MED15,ACLY,PIAS2,CEBPG,LPCAT4,SAMD8,SMPD4,GPI,YY1,RNF14,CDK2,NRBP1,NUDT3,ZNF511,ATXN3,RWDD1,ZBTB37,SUZ12,EIF3D,UROD,ADPGK,SDE2,TERF2IP,SPINDOC,FLAD1,ZNF75D,KDM2A,MTMR4,UCHL5,LPIN2,ADCY9,MRPS27,RNASEH2A,CDK12,SAP30,BRD4,RFC3,ERF,DRAP1,SLBP,ELP4,EDF1,POLG2,GAR1,SERP1,TRIM28,CENPU,PRDM11,SUPT16H,EIF3K,VEZF1,ZNF282,RAD51C,MRPL55,DDOST,HINT1,CERS6,SAFB,GUCY1B1,STAT1,FTSJ1,PPA2,ATF6,BEND3,B4GALT3,EYA2,ATMIN,POLQ,POU3F2,NCOR2,DEPDC1,B4GALT5,TWNK,MECP2,MRI1,TCF3,TKT,AGPAT3,ARGLU1,SECISBP2,MYNN,SDF2L1,BLM,SPR,POFUT1,HMG20A,FOXO3,MAD2L2,PIP5K1C,WWP2,GTF2F1,RFWD3,MAT2B,CCNK,RPL17,ELP5,PTEN,FUT8,PTPN11,MRPL54,RPL19,CARF,CITED2,CNOT6L,CREB1,OSTC,NCOA2,TSHZ1,ZFP64,KAT2A,WDR18,ILF3,RPL8,RFXANK,ADSL,RPL27A,COMMD4,KLF6,GUF1,POLR2A,CBX3,RPL32,ATP5MC3,ZHX1,TFDP1,OAZ2,NAXE,KHSRP,DDX5,TAF6,CPEB2,PURA,RORB,ADA2,POLA2,CCNC,ZNF76,PTMS,PIGM,IER2,KMT2E,PHRF1,MOGS,DNAJC24,ZNF107,TAF6L,SIRT2,SNRPD3,COMMD5,MAPK14,ATP5PF,SNAPC4,MRPL19,ZNF696,BCAT2,MBD4,GOT2,EIF4A3,IMPAD1,JAZF1,PHTF1,AKR1B1,ZBTB22,TCEA1,SLC35C2,TECR,OGG1,ARID4A,CARM1,ELOF1,DEAF1,LARS,DPM1,RIOX2,RRM2,KMT2C,SOX4,PRPSAP1,MPC1,ASF1B,CHAF1A,ABHD5,RPL37,PAF1,GEMIN5,MAN2A2,UBTF,BRWD1,PQBP1,IARS2,CRCP,BAZ1B,ZNF268,CHEK2,GALNT10,CHPT1,MRPL13,RPS26,STARD3NL,RPS15,PIGN,GORASP1,ZNF768,NACA,MED13L,RPL15,MEF2A,THRAP3,TTF1,SRRT,CHKA,LYAR,DTL,NFATC3,ZNF449,MED10,PYURF,ZNF335,BUD31,YBX1,ACAD8,ZNF189,ALDH9A1,VOPP1,ATP5IF1,POLR2I,TSTA3,NUDT4,CIC,RPL6,GBA,EIF2A,SYVN1,SLTM,DAPK3,ISG15,NAP1L1,UAP1,NFIL3,NUP62,DNPH1,ZFP90,RBBP4,NANP,HNRNPDL,NIPSNAP2,PTDSS1,PDSS2,ZBTB24,ADNP2,TCF12,MBD1,PRKAB1,MMACHC,ASH1L,MPHOSPH8,GNPNAT1,UCK2,SMARCA4,UCK1,PLAGL2,NSD3,CHKB,ORC1,IRF3,CHD1,EXT2,MEAF6,MXD1,PAIP1,SAP130,FARSA,RRN3,IARS,CD3EAP,AKAP8,RPN2,CHTOP,UTP4,ZNF770,TMEM14C,RLIM,CSTF1,POU2AF1,ACSL5,CGAS,ZNF500,PCGF6,ATXN1,OGDH,MBD3,EIF3G,RPS9,PDHX,ZNF317,DAP3,STAT6,CHCHD1,ARNTL,CANT1,SCARB1,AKNA,MAPK1,BRD9,ABCA1,CBX4,PDF,NAT14,MIF,DNAJC2,GCLM,CDS2,MRPL42,ZNF316,EYA1,SCYL1,MRPS26,DBF4,KLF13,PAWR,MXD4,PIP4K2A,GFM2,HDDC2,MAN1A1,FGFR3,GART,KMT5A,PELO,RRBP1,NABP2,BRD7,ANP32A,MRPL11,STAT3,MYO5A,SLC25A1,AMPD2,TGFB1,SAMD4B,B3GALT6,GINS1,ELOVL5,ZDHHC18,CSNK1G2,GTF3C6,NASP,PSPC1,HELB,MIER1,NADK2,RCOR1,POLR3GL,MEN1,ATP5MF,ZNF407,SYMPK,TARS,MAPK3,TFEB,CNOT9,MTMR3,UPF1,ATAD2,KMT2B,ACAT1,SRSF3,ZMIZ1,PLOD3,TERF1 |
| 7.525e-27 | -60.15 | GO_NUCLEOPLASM_PART | MSigDB lists | GO_NUCLEOPLASM_PART | 648 | 204 | 17377 | 2626 |
CCNC,ZNF496,MAX,PNISR,THOC1,UBN1,CXXC1,RBM8A,ALKBH5,CSNK2A1,TAF6L,CCNL2,UBE2I,RBM4,POLR3K,PARK7,FANCL,NEK6,EIF4A3,NSRP1,GLIS2,INTS1,SRSF4,TAF5L,OGG1,TIMM50,SRSF10,CDC5L,USP34,FYTTD1,SP3,ERCC1,TRIM8,DDX20,WDR82,TOPORS,EAF2,USP22,LSG1,GINS4,GEMIN5,PAF1,BRMS1,EIF4ENIF1,CHD3,TONSL,LUC7L3,ATXN2L,PQBP1,OGT,CRCP,PRPF4,ACTB,CHEK2,SMNDC1,HDAC2,GEMIN7,DDX42,POLR2K,ZNF768,MED13L,CDK13,THRAP3,EZH1,SUPT7L,METTL3,CDC73,PRPF18,LMNA,RB1,MED8,MED10,INTS7,HDAC7,MBD2,EFTUD2,ZNF335,CTR9,AFF1,GEMIN4,CPSF4,MAML1,LUC7L2,MORC3,POLR2I,ETV3,ELL2,MTA2,TEX10,RTF1,BCLAF1,SRSF5,PATL1,SF3A2,APPL1,DAPK3,MBIP,RBM25,POLR2J,TBPL1,PIAS2,APPL2,RUVBL2,SNRNP70,ZNF830,RBBP4,CDK2,CDKN2A,USP7,MBD1,SART1,SARNP,TRERF1,SF3B1,SUZ12,SUMO2,PRKACA,RPAIN,MEAF6,SAP130,OIP5,MDM2,ZNF473,SP100,BRPF3,PIN1,INTS12,TARDBP,FAM76B,CHTOP,RBM15,ZC3H3,CDK12,RPRD1B,PRPF19,SAP30,NXT1,POLR2G,POLR2L,FAM118B,KAT7,POLR2D,RNPS1,CRNKL1,ELP4,ATXN1,PRPF3,EDF1,TOLLIP,MBD3,FANCE,GAR1,SRSF1,TAF2,HINT1,CLK3,STK38,NSMCE2,HIPK2,ARNTL,COIL,CBX4,INTS2,CTDP1,NCOR2,SRSF6,CBLL1,SMC6,BLM,WDR5,CSNK1A1,GTF2F1,RFWD3,RPA2,KLHL20,PTEN,PPP1R8,PPIG,PRDM4,GEMIN6,H2AFY,SS18L1,FBL,GTF2H2,HNRNPM,MED22,GINS1,YTHDC1,RPRD1A,KAT2A,PSPC1,TOP3A,POLR3GL,MEN1,POLR2A,RPA1,PML,DUSP11,TAF12,SRSF3,ZMIZ1,TAF6,HIPK3,IFI16 |
| 9.545e-27 | -59.91 | MORF_CSNK2B | MSigDB lists | MORF_CSNK2B | 273 | 114 | 17377 | 2626 |
KARS,H2AFZ,HNRNPAB,CHERP,DYNLL1,SUMO2,RAC1,COPE,LAGE3,STARD7,SDHA,GNB2,PARK7,BCAP31,RAD23A,SF3B2,CALM2,HNRNPA2B1,PCNA,RAD23B,CS,HADHB,TARDBP,TCEA1,TECR,GPX4,CCT2,SNRNP200,CDC123,VDAC2,PSMB7,GLO1,TMEM147,CDC23,VDAC1,RFC2,H2AFV,TRIM28,RHEB,SRSF1,KIF2A,EIF3K,DAP3,DDOST,DHX16,PSMD8,TBL3,PPM1G,MPV17,COX5A,UQCRH,KPNA2,SNRPG,AP2S1,PTOV1,COX5B,NDUFV2,MRPL9,NDUFS1,SCAMP3,PHB2,PDAP1,DAP,DCTN2,COX4I1,CYCS,SLC4A2,XPO7,AP3S1,PSMD9,HDDC2,NDUFS4,ERH,NDUFV1,HUWE1,SEC24C,ATIC,BANF1,PTPN11,EI24,NDUFS8,CYC1,PTGES3,FBL,KDELR1,IFRD1,HMGN1,POLR2I,NSDHL,TUFM,JTB,ILF3,DDX39A,COMMD4,EIF4H,MAP2K2,SF3A2,SNRPA,CBX3,SDHB,PDCD6,PRDX3,MFAP1,RBMX,PRPS2,ACLY,IMPDH1,MDH1,NDUFS5,GPI,RUVBL2,SRSF3,RBBP4,ESPL1 |
| 9.912e-27 | -59.88 | SHEN_SMARCA2_TARGETS_UP | MSigDB lists | SHEN_SMARCA2_TARGETS_UP | 407 | 148 | 17377 | 2626 |
UBL3,RAB14,TMED7,ST13,NDUFB6,NF1,TMEM41B,YTHDC2,TGOLN2,GYG1,UBQLN2,MBD4,ATG3,RAB4A,SRI,FBXW2,SUCLG2,NFU1,SRSF10,COPS8,SP3,DPM1,TLK1,PRKRA,RAB22A,KRIT1,SMAD2,WDR11,FBXO28,TMED10,LUC7L3,U2SURP,ROCK1,ATP6V0E1,NUMB,RMND5A,PRPF38B,NSMCE4A,PPP1R2,RAB23,CTCF,NCKAP1,CD59,RB1,SMC3,RBM34,XPA,CTR9,KIFAP3,AGGF1,CREG1,DHX29,ZMYND11,CAMSAP1,MAP4K3,BCLAF1,CAPZA2,ARMC8,SLTM,MATR3,XRCC5,CAND1,ADSS,RNF14,TMEM14A,RNF114,FAM208B,SUCLG1,RAF1,CAST,UBR2,TMX4,TOR1AIP1,ACTR3,DAZAP2,RCOR3,KTN1,PAIP1,PRKD3,RAB21,ZNF302,RALB,NSFL1C,SOCS6,CDKN1B,APOOL,CHTOP,ABI1,KDM3B,SHOC2,HMGN4,EID1,RAB7A,ATXN1,CDC23,RAB1A,H2AFV,MRPS14,GLOD4,AMZ2,PON2,IDE,TAB2,RNF38,NCOA1,SMAD4,ATMIN,COMMD10,PKP4,SMAP1,TRIP12,MECP2,VPS45,SLC25A12,LANCL1,HMG20A,FBXO3,TANK,PTPN11,ANP32A,FEM1B,UPF2,YTHDC1,MOB4,STAU1,DCAF6,RPRD1A,SNX2,NEK7,TMEM126B,DENND4C,MRS2,METTL5,PPWD1,RHOT1,MACF1,TTC33,RPA1,SEC23IP,TWSG1,OSBPL8,HNRNPH3,CAPN7,MRFAP1L1,RBPJ,PREPL,PURA,TMEM131 |
| 1.031e-26 | -59.84 | MITSIADES_RESPONSE_TO_APLIDIN_DN | MSigDB lists | MITSIADES_RESPONSE_TO_APLIDIN_DN | 240 | 105 | 17377 | 2626 |
TMEM106C,USP7,TOMM20,NUP188,HNRNPAB,FOXM1,SF3B1,MAGED1,PTTG1,TMEM97,TPX2,CSNK2A1,CCNB1,PPP1R16B,MRPL19,CPNE3,FANCI,CALM2,CCNA2,NUP210,MTMR4,DUT,KIF14,ATP13A3,PDS5B,TTC3,TARDBP,TACC3,SEPT9,CUL3,MKI67,RRM2,ATXN1,NUSAP1,SMC2,BICD2,MCM2,SHCBP1,CBFB,EIF3A,CHAF1A,SUPT16H,ANKRD10,TRAM2,KIF18B,HNRNPR,PDXK,NGLY1,TUBB,POLQ,WSB2,KIAA0100,HJURP,CASP6,MUM1,CDT1,CENPF,CDCA8,RRM1,CERK,RACGAP1,NOTCH2,BLM,NCAPG,RAB11A,NUP205,FBXO5,PSMD2,ADD3,SMC3,MCM5,FUT8,MSH2,PTPN11,AHCY,LPCAT1,IMPA2,MSH6,GINS1,ZFP64,ASPM,DENND1B,PRKDC,NSDHL,SUGP2,CAMSAP1,MYBL2,PLEC,NFATC2IP,MACF1,SNRPA,CBX3,DERL1,EPRS,PALB2,BIRC5,OSBPL8,TFDP1,MAPK6,ACLY,IMPDH1,WDR76,GPI,PGAM1,ZC3HAV1 |
| 1.341e-26 | -59.57 | cellular protein localization | biological process | GO:0034613 | 1388 | 357 | 17256 | 2622 |
TMED7,RAB14,TXN,NUP188,TSC2,AP3M2,SYNRG,RIC1,PARK7,MIS12,RPL23A,CDK5,NAPG,SNUPN,RABGAP1L,RAB4A,SRSF4,AP1M1,AP2B1,NUP153,SEH1L,SRP72,USO1,ATG9A,AKT2,NOL8,MRNIP,TOPORS,NUTF2,AURKB,ICMT,RAB22A,RAB2B,ARF4,HHEX,TMED10,RPS27A,RPS14,EIF2D,VIPAS39,RRS1,SLF1,NMD3,LONP2,AAAS,NXT2,MAPRE1,GGA1,SEC61G,DHX9,RAB23,TMED3,SUPT7L,VPS25,COPG2,LMNA,SPAG5,NPLOC4,COPB2,ATG4A,RTKN,TMEM250,FBXO7,TNPO3,PIKFYVE,CPSF4,SYTL3,NUP85,TMED2,MORC3,TERF2,SRSF11,NAGPA,EIF5A,TIMM8B,GCC2,RPS10,RPS24,SEPT8,SSR2,SRSF5,MTX1,TOMM40,PTTG1IP,RHOB,XRCC5,DERL1,SEC31A,SCARB2,FNTA,KPNA1,NSF,FAM83D,PPP3R1,WIPI2,SGF29,NUP58,EXOC3,NDC1,SARNP,SYS1,RAB11B,ANK3,VTI1A,TBC1D13,AP1B1,STAM,MOAP1,TERF2IP,RAB21,SP100,TBC1D22A,TBC1D14,NUP107,SEPT11,TNPO2,ANKRD13C,ZC3H3,ARL5A,SNX8,SEC61B,INTS13,RNPS1,POLR2D,RPL38,SLBP,DNAJA1,RAB1A,AP4E1,PEX5,CHMP4A,HSPA4,SEC61A1,VPS26B,RAB24,CCDC14,RPLP1,SEL1L,PITRM1,CSNK1D,RPS2,MZT1,SRSF6,FLOT1,TRAK1,SPDL1,IFT27,RAB11A,WRB,RPA2,RPL17,AXIN2,DCP1A,RPL19,UPF2,MTX2,PACS2,PPP3CA,TNFAIP3,DENND4C,RPL8,PACS1,RAB3IP,DDX39A,MACF1,RPL27A,SH3GLB1,RPA1,HGS,RPL32,STX18,PML,SSNA1,CD81,YWHAH,WDR45B,IPO4,VPS29,SNAPIN,POLA2,MTX3,COPA,THOC1,AGRN,RBM8A,SNX15,ALKBH5,AGFG1,BECN1,SEC16A,SSR1,RAB8A,NUP210,TIMM23,EIF4A3,AP3S2,RAB35,ATG3,ZFYVE27,RPF2,CARM1,TIMM50,PTPRK,CDC37,PLK1,FYTTD1,LARS,SEPT9,MIOS,TLK1,EZR,ANLN,RAB5B,STX16,OPTN,RPL37,PAF1,TRAM2,SEPT1,TBC1D17,TIMM13,GRIPAP1,TIMM29,MIA2,KPNA2,VPS4A,ROCK1,DVL1,CLU,RPS26,POT1,C2CD5,RPS15,TBC1D12,PHB2,NKD2,LAMTOR3,TIA1,RPL15,CTCF,RAB6A,XPO7,RAPGEF6,RHBDD1,NUP205,RB1,KIF13B,XPA,PPIL2,ARL6IP1,YBX1,GLE1,MCPH1,LRSAM1,PREB,KDELR1,RPL6,SYVN1,SEPT7,ZDHHC3,RPL36,TSC1,PCM1,GOLGA4,LAMTOR4,EXOC4,ZDHHC7,SIL1,NUP62,CTSA,RUVBL2,SNX27,TOMM20,RPLP2,TOR1AIP1,RRAGC,TWF2,RPAIN,BCAP31,RPL11,HNRNPA2B1,ANKLE1,MDM2,SAR1A,BCAP29,AHCYL1,CLTB,CHTOP,LMAN1,DVL2,CHP1,PRPF19,RPL29,NXT1,RPL35,RAB7A,TOR1AIP2,NUP155,BICD2,ERBIN,ARL5B,TOLLIP,RPS9,RPSA,SRSF1,SURF4,VPS26C,TIMM17A,TULP3,ARNTL,AP1S1,CHMP4B,SMURF1,AP2S1,TSPAN5,PARD3,TMEM33,CDC40,GOLPH3L,KLHL21,RAE1,DCTN2,SRGN,NUP54,VPS45,ARFIP2,TIMM21,GGA2,AP3S1,SEC24C,NABP2,ARHGEF2,H2AFY,ATG13,STAT3,MYO5A,TGFB1,ZDHHC18,SNX2,RANGAP1,SYMPK,MFN2,LEMD2,RAB18,SEC23IP,UPF1,ATP6V1D,PDCD6,KPNA4,GOLGA7,OSBPL8,FAM126A,CENPT,SPCS3,SRSF3,CHMP7,SLF2 |
| 1.400e-26 | -59.53 | RNA splicing | biological process | GO:0008380 | 394 | 145 | 17256 | 2622 |
DDX47,THOC1,RBM8A,DHX8,USP39,SNRPD3,RBM4,PAPOLA,SF3B2,SNUPN,NSRP1,EIF4A3,METTL14,SRSF4,GPATCH1,KHDC4,TRA2B,ECD,CCAR1,PCBP2,SRPK2,SRSF10,CDC5L,SNRNP200,SNRPB,HNRNPF,DDX20,SREK1,LUC7L,CLNS1A,DHX15,IWS1,GEMIN5,LUC7L3,U2SURP,PQBP1,PRPF4,SMNDC1,GEMIN7,DDX42,PRPF38B,LIME1,ZCCHC8,POLR2K,DHX9,CDK13,THRAP3,PRPF39,PDCD7,METTL3,SRRT,PRPF18,RAVER2,SNRNP25,EFTUD2,BUD31,RTCB,ZNF326,YBX1,GEMIN4,CPSF4,PABPC1,LUC7L2,SRSF11,POLR2I,SF3B6,SUGP2,SRSF5,SF3A2,RBM38,SYNCRIP,RBM25,POLR2J,RBMX,PRMT7,ZNF830,SNRNP70,TSEN15,SART1,CHERP,IVNS1ABP,SF3B1,XAB2,RRAGC,C2orf49,PCBP1,HNRNPA2B1,TARDBP,AQR,RBM15,STRAP,CDK12,PRPF19,CSTF1,POLR2G,POLR2L,PPIE,RNPS1,POLR2D,CRNKL1,SMU1,LSM8,PRPF3,BUD13,TXNL4A,SRSF1,DDX17,SUGP1,PPP2CA,LSM6,HNRNPR,DHX16,SNRPG,FUS,PRPF4B,CWC25,CDC40,SRSF6,HABP4,JMJD6,GTF2F1,RBM17,DNAJC8,CTNNBL1,CWC27,PPP1R8,PPIG,GEMIN6,HNRNPM,RBM15B,YTHDC1,PPP1R9B,PSPC1,PPWD1,DDX39A,SYMPK,SNRPA,POLR2A,DDX23,HNRNPH3,KHSRP,DDX5,ZRANB2,SRSF3,WDR62 |
| 1.494e-26 | -59.47 | organonitrogen compound metabolic process | biological process | GO:1901564 | 5382 | 1054 | 17256 | 2622 |
HEXB,TGOLN2,RBM4,FBXO22,EEF2K,RPL23A,RAD23B,UPRT,CRY2,RNF26,TIPARP,ANKRD9,MGAT5,RHBDD2,MRPL57,USP34,BAK1,NRAS,EHMT1,MIER2,ARF4,SMAD2,RAD18,RPS27A,OGT,COX5A,RNASEL,KLHL42,SMAD1,CHPF2,OAZ1,ZNF720,CLSPN,GGA1,TRIO,RAB23,KCTD17,EIF2AK4,PSMD9,APH1B,CDC73,ATG4A,PDXP,RNFT1,FBXO7,EFTUD2,MRPL21,NUP85,PABPC1,PHKG2,PPA1,EIF3L,FOXK1,MAPKAPK3,MTA2,ERO1A,USP10,MRPL16,EIF4H,FNTA,TYW5,WIPI2,CFAP20,MRPL3,NUP58,TRIM41,KARS,PTTG1,STARD7,SLC35B2,INO80E,GLRX3,CPNE3,FBXL6,MTA1,UBA5,NSFL1C,GPD1L,RPRD1B,PDCL3,CPNE1,ULK3,SEC61B,ERMP1,KAT7,RPL38,RAB1A,PPP2CA,ALDH3B1,NSMCE2,CAMKMT,RNF38,DMWD,PPP5C,PITRM1,USP13,ZFP91,CCM2,ABHD14B,ATP5F1B,WDR5,NEIL2,PPP1R3B,GOLM1,PSMD2,CLIC4,ITGB8,HUWE1,NAA50,LTN1,KANSL2,UBE3B,ST8SIA2,GTF2H2,FBXL19,RPL22L1,SPTAN1,USP42,LDHA,SLC19A1,MAGT1,GPS2,PARG,DBI,PARP10,WDR45B,TRIM11,ZER1,CREM,TET3,FANCL,RAB8A,NUP210,SLC44A1,EIF5,MTPN,ASB6,RYBP,PLK1,PTPN18,RBX1,APH1A,SNRPB,UBE2V1,KRTCAP2,ODC1,USP21,TRIM4,ALG3,CHD3,ARRDC1,ADAM9,CLN3,NGLY1,RMND5A,LAMTOR3,SDC2,COX4I1,ADCK5,CDK13,RAB6A,RSAD1,C1GALT1,UBE2Q2,CCP110,CTR9,AHCY,MRPL48,LRSAM1,DCAF8,LDB1,AMD1,MAP4K3,METTL22,ARMC8,STYXL1,NMT2,RPL36,MBIP,GALNT2,ORMDL2,COX7A2L,ZDHHC7,RUVBL2,ECPAS,USP7,TRAF7,RPLP2,ATP6V1B2,LYN,MRPL50,PSMA6,KMT5C,BRPF3,ABRAXAS2,PIN1,PPME1,LMAN1,AHCYL1,CTDSP2,SPSB3,PRPF19,PPIF,KDM3B,BIRC3,PPT1,RAB7A,PPIE,NUP155,MRPS14,RHBDF2,EIF3H,IDE,UBXN2B,FASTK,STK38,UHRF2,CHMP4B,H3F3A,CHID1,SMAD4,NADSYN1,KLHL21,AGO2,CDCA8,TMX3,CDK11B,SCYL2,DNAJB9,HERC3,CTSS,RNF5,RNLS,RHOA,RPRD1A,PRKDC,TUFM,RANGAP1,PNPLA8,PCGF1,HAGH,PDCD6,NEK1,CTBS,IMPDH1,USP20,TAF12,PGAM1,HIPK3,IFI16,TXN,NUP188,PDCD6IP,GXYLT1,ADAM10,PRKCSH,CXXC1,CUL1,USP39,UBE2I,OAT,PARK7,ASPHD2,AP2B1,FBXW2,TAF5L,SLC26A2,MARCH2,LACTB,USP22,CBFB,EIF3A,DOT1L,MAP3K4,MKNK1,RPS14,TPP2,MRPL27,PTPDC1,CCDC59,B4GALT2,COX5B,DHPS,PRKAA1,GSPT2,RRM1,B4GALT1,CYCS,SUPT7L,PSEN1,TMEM165,VPS25,NDUFS7,NPLOC4,WDR48,RPN1,KLHL5,ZNRF2,PPP4R1,MSH2,TPST1,DAPK1,PIGG,FBXL7,MRPL40,CYC1,APOL1,SOCS5,EIF5A,PIGT,CPQ,COQ8A,MFNG,USF3,RPS24,ADRB2,MTR,MAP2K2,DERL1,CAT,MTHFD2,GOLGA2,EPOP,RBMX,PIAS2,USP32,SAMD8,SMPD4,GPI,NUDT3,NDC1,ATXN3,TP53RK,RAB11B,RAF1,UROD,CD320,CCNA2,SIAH1,MTMR4,LPIN2,ADCY9,SOCS6,MRPS27,TTC3,ILKAP,CDK12,CFL1,SAP30,ELP4,PKMYT1,ASB13,ERC1,SERP1,TRIM28,AMZ2,EIF3K,ANKZF1,DDOST,HINT1,CERS6,FTSJ1,BEND3,EYA2,PRPF4B,ADAM23,NDUFS1,B4GALT5,MECP2,MANBA,TKT,CBLL1,SECISBP2,POFUT1,WWP2,RFWD3,CCNK,NDUFA2,FUT8,PTPN11,AXIN2,MRPL54,FEM1B,RPL19,NDUFA3,KAT2A,LONRF3,ADSL,FBXO9,OTUD3,ARSK,GUF1,SPPL2B,FADD,RPL32,OAZ2,PPP1R11,DUSP11,NDUFS5,WDR91,ESPL1,DDB1,CCNC,PIGM,KMT2E,UQCR10,UBE2Q1,PTP4A3,ATP5PF,MRPL19,PCYOX1L,CDC42,GOT2,SLC35C2,CARMIL1,CARM1,SRPK2,LARS,NCK1,LAP3,VHL,RIOX2,SUMF2,KMT2C,MPC1,RPL37,MAN2A2,PPM1G,CAB39,BAZ1B,STK11,CHEK2,CLU,VPS4A,CHPT1,MRPL13,DCAF5,CAPN1,UBE2D3,PPP1R12A,GORASP1,UBXN1,PCSK7,RPL15,PM20D2,XPNPEP3,TTF1,NUP205,CHKA,DTL,MED10,PYURF,TENM3,ZRANB1,CSNK1G3,ATP5IF1,ERLIN1,NUDT4,RPL6,GBA,EIF2A,SYVN1,VKORC1,DAPK3,MASTL,KLHL15,SIAH2,FN3KRP,DNPH1,CTSA,APOL2,PRKAB1,MDH2,UCK2,UCK1,EXT2,USP5,UBXN2A,IARS,KIF14,PPP6C,CHP1,HPDL,PGGT1B,RNF25,PCGF6,GLO1,OGDH,EDEM2,TOLLIP,MBD3,RPS9,PDHX,ARNTL,FKBP5,MAPK1,ABCA1,PDF,GCLM,TRIP12,SHPRH,RAE1,SCYL1,NUP54,PAWR,DCUN1D4,GFM2,SPPL2A,FASTKD3,FGFR3,GRK2,KLHL20,KMT5A,PPIG,RRBP1,NDUFS8,FBL,SLC35A1,AMPD2,TGFB1,B3GALT6,ELOVL5,DCAF6,HEMK1,MIER1,NADK2,RFFL,RCOR1,PRMT2,CDK11A,MTMR3,CTSL,DTX4,KMT2B,ACAT1,PLOD3,HRAS,FGFR1OP,ADD1,MAP3K7CL,MRPS15,KDM4A,PIGQ,XIAP,GLUD1,PABPC4,CDK5,PSMD1,NEK6,FNIP2,NUP153,SENP1,PCBP2,KCNAB2,PGAP2,PLK3,TMEM115,MRPL43,TOPORS,DCUN1D5,ICMT,STOML2,BRMS1,AXIN1,LIMK1,VIPAS39,ATE1,ST3GAL2,FBXL3,LONP2,PFKP,AAAS,NDUFV2,MRPL9,MRPS2,CERK,TOP2B,ZNRF3,EZH1,DDRGK1,MCTS1,GNS,EIF2S2,CARS2,UBE2QL1,NAGPA,DHX29,MAN1B1,RPS10,ARMT1,ABCF1,PTPRF,CSK,DUSP3,TEX30,SETD3,PTAR1,MDH1,HEXA,RNF139,SGF29,EGLN1,ABCA3,UBR2,WDTC1,MYH9,NIT2,RXYLT1,EFL1,PRKACA,APP,KTN1,ANKIB1,STAM,PRKD3,DUT,DDA1,NUP107,ANAPC7,MAVS,RNF19A,CLN6,ATF2,RNF169,ADCY7,ENPP4,MAP4K4,ATP6V0A1,NDUFA7,TAZ,FKBP3,CDC16,PEX5,HIPK2,RPLP1,MBOAT1,PDXK,LRP8,GALK1,RPS2,TRAK1,JMJD6,UBE4A,FBXO3,CAPN2,ERH,SUV39H2,GATC,NDUFB4,PRDM4,GTSE1,TTLL12,LYPLA2,LDHB,PDPK1,PPP3CA,TK1,GUK1,TNFAIP3,GALC,MRPS10,PDE3B,ZNF862,KEAP1,CAPN7,MAPK6,PML,SLC25A19,PSAP,FAF1,ANAPC4,SNAPIN,SRM,COX15,AGRN,PPP1R15B,MCCC1,CSNK2A1,BIRC2,ABL2,PCNA,PPCDC,MRPL32,PTPRK,CDC37,ABCC5,SP3,BAZ2A,HARS,TLK1,MRPL12,GMFB,BRCA1,ESYT1,PRKRA,NAGLU,SOCS4,QRSL1,ACTB,DHFR2,OSGEPL1,NUDT11,NAA60,SEPHS2,TMUB1,ASAH1,PPP3CB,B4GALT4,ASXL2,RLF,NUS1,MED8,PPIL2,MDFIC,ALDH18A1,MAML1,ABCC1,RTF1,EIF2AK1,KRAS,NFATC2IP,UBE4B,LY6E,EIF4G2,ZDHHC3,PSMC4,CDC27,PRPS2,TBPL1,PRMT7,ATP5F1A,RNF114,KCTD7,NDUFA5,CYLD,MRPL39,SUMO2,DUSP22,RPL11,RAD23A,SEC11A,PDK2,MDM2,MRPL34,MINPP1,SAP30L,GM2A,RPL29,RPL35,PSMA8,BTG2,CPOX,MTMR6,KDM1B,USP36,RPSA,DNAJC10,MRPL2,CLK3,PSMD3,NDUFA11,NCOA1,LTA4H,USP53,SLC25A39,AP2S1,ZC3HC1,CTDP1,SUMF1,CHAC2,GGA2,CSNK1A1,PTPN2,IRF4,GSTK1,NDUFV1,CWC27,CAMK2G,CNTN5,PPWD1,NEU1,FBXO41,GOLGA7,BIRC5,ACADM,SPCS3,RPS6KC1,UBE2C,SAT2,GCSH,PPCS,NDUFB6,ZDHHC8,NHLRC3,CCNB1,EIF1B,MAST2,CDC25B,SPTSSA,SEH1L,PBK,AKT2,AURKB,GALNT7,MCFD2,CCNF,STT3A,PSMD8,EIF2D,PTPN7,DHTKD1,UQCRH,ARRB2,ZNF598,HDAC2,DDX58,WSB2,PPIB,MUT,GMFG,ADO,NDUFA4,MAN2B1,NDUFS4,CFLAR,FKBP1A,RNF121,DAD1,ATIC,HDAC7,CTPS1,ATP6V0A2,RNF135,LPCAT1,EEF1D,MORC3,NOA1,DCTD,CYFIP2,PKM,KDM3A,PSMB3,ADSS,EPRS,DCK,QARS,CSNK1G1,ACLY,PPP3R1,LPCAT4,DCAF11,VCPIP1,MAP3K5,YY1,CDK2,RNF14,NRBP1,ZC3HAV1,RWDD1,SUZ12,RPS6KA1,EIF3D,RAC1,OLA1,KLHL18,ADPGK,SDHA,FLAD1,CRKL,APLP2,KDM2A,SHC1,UCHL5,TALDO1,NAA35,TAOK1,CUL3,KIAA1586,CDC23,PSMB9,POLG2,SOCS7,PPP2R5A,MRPL55,JAK1,GUCY1B1,PPA2,SEL1L,TRIM32,B4GALT3,CSNK1D,OTUD5,MRI1,BABAM1,CDCA3,BRAP,SDF2L1,SPR,RAB11A,PTEN,RPL17,CRAT,COPS7B,OSTC,CREB1,MAP3K14,UBE2M,NEK7,RPL8,PARP4,ILF3,TBRG4,ANAPC2,RHOT1,RPL27A,MARK2,NUCB1,FBXO21,SGSH,HGS,TTLL4,PRDX3,ATP5MC3,NAXE,CPEB2,ESYT2,ADA2,MIB2,UBE2E2,NF1,DCAF15,MOGS,DNAJC24,UBE2Z,SIRT2,TAF6L,SNRPD3,UBQLN2,USP48,FKBP2,MAPK14,BECN1,RNF103,MBD4,UBLCP1,BCAT2,IMPAD1,ATG3,SRI,AKR1B1,JOSD1,NDUFB9,NFU1,OGG1,ARID4A,FGFR1OP2,TIMM50,COPS8,TRIM8,DPM1,WDR82,STK17B,GEMIN5,PAF1,UEVLD,IARS2,GALNT10,ROCK1,COPS6,RPS26,PSMC1,RPS15,PIGN,UFC1,MEF2A,RHBDD1,ZNF335,YBX1,GLTP,BCL2,UBE3C,ACAD8,ALDH9A1,PSMA1,ISG15,CAND1,NUP62,NAA20,RBBP4,NIPSNAP2,PTDSS1,MMACHC,ASH1L,TOMM20,MPHOSPH8,WDYHV1,NSD3,IRF3,CHKB,PAIP1,MEAF6,FARSA,BABAM2,PARL,RPN2,PDIA6,TMEM14C,SCYL3,ABI1,HTRA2,RLIM,PSMB7,NLN,NDUFB1,PEF1,EIF3G,BTBD1,DAP3,TAB2,CHCHD1,CANT1,USP11,SMURF1,PPP2R2D,TSPAN5,CBX4,MRPL42,SH2D3A,CASP6,EYA1,SRGN,MRPS26,HDDC2,MAN1A1,GART,TANK,PELO,MRPL11,CSNK1G2,ZDHHC18,ADAM17,PRKAR1B,WDR81,MEN1,ATP5MF,TARS,HSPA1B,MAPK3,PLAA,OSBPL8,KBTBD7,COX8A,MBD6,PREPL |
| 1.859e-26 | -59.25 | cellular component organization or biogenesis | biological process | GO:0071840 | 5595 | 1088 | 17256 | 2622 |
HEXB,TGOLN2,RPL23A,NAPG,DNAAF2,RAD23B,AP1M1,DNM2,RNF26,FTSJ3,MRPL57,BAK1,ERCC1,RHOBTB3,NRAS,GABPA,EHMT1,WDHD1,MIER2,MCM2,RAB22A,ARF4,GINS4,AHNAK,MID1IP1,SMAD2,RPS27A,MYO18A,OGT,MPV17,RNASEL,SMAD1,SLC25A33,RHOC,MUM1,DHX9,RAB23,KCTD17,HAUS4,EIF2AK4,PSMD9,HAUS2,CDC73,ATG4A,TFAP4,CD59,PDXP,SMC3,MEGF8,FBXO7,GEMIN4,MRPL21,NUP85,NSUN4,PPP6R1,LUC7L2,IFRD1,MTA2,MTFR2,ERO1A,GTPBP4,MAP7D1,MRPL16,MTX1,EIF4H,FNTA,KPNA1,WIPI2,ZNF830,CFAP20,RUFY3,MRPL3,NUP58,ALS2,RHOG,POC1A,PTTG1,ANK3,C5orf30,VTI1A,TPX2,INO80E,GLRX3,STMN1,REPS1,AHCTF1,SH3BP1,MTA1,CLCN6,NSFL1C,SEPT11,SNX8,CPNE1,ULK3,FAM118B,GOPC,KAT7,CRNKL1,RPL38,CIRBP,POLR2D,GORAB,RAB1A,TANC1,MAT2A,PPP2CA,KIF2A,LSM6,CORO1C,NSMCE2,CAMKMT,SNRPG,PPP5C,PITRM1,TUBB,MZT1,SRSF6,CCM2,FLOT1,ATG2B,ATP5F1B,WDR5,IFT27,RRP36,SAPCD2,GOLM1,RPA2,PDCD10,CLIC4,ITGB8,HUWE1,NAA50,KANSL2,NAP1L4,GTF2H2,SPTAN1,TCTEX1D2,TACC1,HEBP2,LLPH,RAB3IP,PICALM,UTP20,SSNA1,YWHAH,WDR45B,KRR1,PRNP,TET3,RAB8A,NUP210,TIMM23,NOC2L,EIF5,MTPN,TACC3,RYBP,PLK1,RPP25,CELSR2,SEPT9,RBX1,SNRPB,PSMG1,PBRM1,UTP3,LUC7L,USP21,LSG1,TRIM4,TRAM2,CHD3,GRIPAP1,E2F4,ARRDC1,DVL1,CLN3,POT1,NUMB,HJURP,PHB2,CENPF,NKD2,SDC2,KLC1,CHCHD2,NCKAP1,ARID1B,CCP110,MBD2,SSBP3,XPA,ARL6IP1,CTR9,MRPL48,ACSL3,LDB1,CAMSAP1,ICAM2,BBS12,HAUS8,RPL36,MBIP,PCM1,LAMTOR4,RUVBL2,MYO9A,ECPAS,CCNB2,UNC13C,BCCIP,USP7,SART1,RPLP2,ARID2,NDUFAF2,TOR1AIP1,SLC2A1,ATP6V1B2,LYN,OIP5,VAV1,MRPL50,NRF1,KMT5C,BRPF3,ABRAXAS2,PIN1,TARDBP,LMAN1,TOP1MT,STRAP,PRPF19,PPIF,KDM3B,ARHGAP17,MND1,CLCN3,BIRC3,PPT1,RAB7A,NUP155,DCLRE1C,CHMP2B,MRPS14,AFDN,IDE,RBL1,UBXN2B,CHMP4B,XRCC3,H3F3A,SMAD4,RAD51D,PARD3,NIFK,UNK,MTERF1,AGO2,CDCA8,GTF3A,HMGN3,ARF1,SLC12A9,NCAPG,TUBGCP2,CTSS,POLR1B,ORC3,YTHDC1,PPAN,ACP2,RHOA,HMGN5,PRKDC,TOP3A,RANGAP1,PCGF1,DDX23,RAB18,CACNB1,SEC23IP,PDCD6,NEK1,ATP6V1D,L3MBTL3,E2F1,TAF12,NUP188,MAX,H2AFZ,PDCD6IP,ADAM10,CXXC1,CUL1,USP39,OAT,PARK7,PA2G4,MTFR1L,NOL11,TRA2B,AP2B1,TAF5L,CISD2,SMARCE1,SRSF10,SGCE,USP22,RFC2,CLNS1A,EIF3A,PRIM1,ZMYM3,DOT1L,HHEX,WAS,KIF18B,BRD2,RPS14,LUC7L3,MRPL27,MAP4,PTPDC1,NMD3,RECQL,DHPS,VAV2,PRKAA1,GSPT2,RRM1,DNAAF5,B4GALT1,CYCS,SUPT7L,PRPF39,PSEN1,TMEM165,VPS25,NDUFS7,NPLOC4,SPAG5,RTKN,TMEM250,EXOSC7,ARPC5,MSH2,FBXL7,MRPL40,TNRC18,MRM3,SYTL3,GCC2,PRIM2,WDR1,RPS24,GORASP2,EXOSC9,ARID1A,CAPZA2,ADRB2,GOSR1,MTR,CCT8,XRCC5,PI4K2A,DERL1,SEC31A,CAT,GOLGA2,EPOP,RBMX,ARAP1,CABIN1,CDKN2A,NDC1,ATXN3,REPS2,RAF1,POMP,BCL2L1,DECR1,CCNA2,SIAH1,MRPS27,TAP2,TP53BP2,CFL1,SAP30,ANKLE2,BRD4,CDC123,LRRC8A,ELP4,SERP1,TRIM28,EML4,SUPT16H,RAD51C,CHMP4A,DSN1,SAFB,BEND3,EYA2,DYNC1LI2,NDUFS1,MECP2,SPDL1,HMG20A,SLC25A36,NDUFA2,PTPN11,AXIN2,MRPL54,RPL19,CNN2,NDUFA3,MTX2,MSH6,KAT2A,TMEM126B,RABIF,ADSL,BMS1,MACF1,KIF11,FADD,SH3GLB1,CBX3,INF2,TMEM127,RPL32,NDUFS5,WDR62,TAF6,ESPL1,PURA,DDB1,IPO4,POLA2,MTX3,KMT2E,UQCR10,BRIX1,MAP1LC3B,ATP5PF,MRPL19,DST,CDC42,SYNM,RAB35,RPF2,CARMIL1,CARM1,SRPK2,LARS,SNRNP200,NCK1,VHL,RIOX2,TMEM216,PITPNB,KMT2C,ASF1B,RPL37,HSPB11,BRWD1,NIP7,MIA2,CAB39,BAZ1B,STK11,CHEK2,CLU,VPS4A,MRPL13,ATP6V0E1,CAPN1,PPP1R12A,GORASP1,EPN1,RPL15,NUP205,PRPF18,LYAR,TENM3,ZRANB1,MCPH1,SLC12A2,ATP6V0D1,ATP5IF1,RPL6,GBA,EIF2A,DAPK3,MASTL,SIAH2,SLC16A1,YWHAZ,EHD4,TMEM14A,CHMP2A,PRKAB1,CORO7,FEZ2,SMARCA4,HNRNPA2B1,RRN3,UBXN2A,NVL,KIF14,EXOSC1,PPP6C,CLTB,UTP4,CHP1,PCGF6,BICD2,CADM1,MBD3,RPS9,SURF4,HPS5,ANP32E,MAPK1,BRD9,ABCA1,TMEM33,DNAJC2,GCLM,SHPRH,RAE1,DCTN2,NUP54,PAWR,GFM2,FERMT3,KIF5B,FASTKD3,KLHL20,KMT5A,SEC24C,H2AFY,ARHGEF2,ANP32A,ATG13,NDUFS8,FBL,STAT3,MICAL3,MYO5A,TGFB1,COA3,PPP1R9B,TIMMDC1,HELB,MIER1,ATP2C1,COG1,RCOR1,PRMT2,TFEB,LEMD2,CTSL,UPF1,ELMO1,KMT2B,ACAT1,CENPT,ZMIZ1,PLOD3,HRAS,TERF1,FGFR1OP,RAB14,TMED7,ADD1,MRPS15,KDM4A,XIAP,GLUD1,CNTROB,MIS12,CDK5,NEK6,PDS5B,NUP153,MLST8,PLK3,AATF,MRPL43,TOPORS,MCL1,SMC2,STOML2,BRMS1,AXIN1,LIMK1,VIPAS39,ATP6V0C,TFDP2,LONP2,AAAS,SSRP1,NDUFV2,MRPL9,MRPS2,PHF23,TOP2B,TMED3,EZH1,ITGB5,LMNA,MCTS1,DDX56,NAGPA,CYFIP1,TIMM8B,RB1CC1,TSPYL4,ZMYND11,TEX10,MYBL2,RPS10,SRSF5,RHOB,NCDN,PTPRF,SCARB2,CSK,TEX30,SETD3,NDE1,SNX14,SGF29,ZNF207,ANKRD27,UBR2,ACTR3,CHD1L,WDTC1,MYH9,NUF2,EFL1,PRKACA,STAM,APP,RAB21,CLUAP1,SP100,ATP2A2,UTP18,NUP107,CEP63,RNF19A,CLN6,ATF2,DCTN1,ATP6V1G1,PSRC1,MAP4K4,INTS13,ATP6V0A1,NUSAP1,NDUFA7,TAZ,DDX17,CHCHD3,TAF2,PEX5,SEC61A1,HIPK2,RPLP1,RPS2,ANXA6,TRAK1,JMJD6,AKT1S1,ETS1,WRB,PNO1,KRI1,CAPN2,ADD3,SUV39H2,NDUFB4,PRDM4,GEMIN6,SGCB,S100A6,LYPLA2,NUDC,PDPK1,TK1,TNFAIP3,JTB,MRPS10,EMP3,RPA1,KIF18A,POLE,CCDC6,PML,HMGB2,SNAPIN,COX15,DDX47,AGRN,MCCC1,EBNA1BP2,S1PR2,SEC16A,BIRC2,ATPAF1,DLG5,PCNA,ETV6,XRCC2,ZFYVE27,MYBL1,MCMBP,MRPL32,PTPRK,EXOSC6,BAZ2A,TLK1,MRPL12,GMFB,EZR,LNX2,LRP5,BRCA1,ANLN,RAB5B,STX16,OPTN,DPYSL3,EPB41,SEPT1,TIMM13,NAGLU,ACTB,C2CD5,NAA60,GEMIN7,CTCF,RACGAP1,PPP3CB,RLF,RAPGEF6,RB1,VASP,VMP1,PREB,ABCC1,TRAPPC9,UTP15,RTF1,KRAS,UBE4B,ARPC1A,GOLGA4,SNAP23,TBPL1,PRMT7,ATP5F1A,KCTD7,NDUFA5,CYLD,XAB2,DYNLL1,MRPL39,RPL11,ATP6V0B,MDM2,MRPL34,CORO1A,SAP30L,DVL2,RPL29,RPL35,TIMP2,BTG2,TUBGCP5,FRAT2,PRPF3,KDM1B,TXNL4A,USP36,RPSA,SRSF1,MRPL2,TIMM17A,CEP55,NDUFA11,NCOA1,AP2S1,CTDP1,RRP15,CDT1,ARFIP2,SMC6,CSNK1A1,TFRC,IRF4,STARD9,NDUFV1,ABCD1,SS18L1,DDX31,PTGES3,CENPM,CAMK2G,SNX2,ZMYM5,RHOT2,CHCHD6,BIRC5,SNAP29,PKD2,UBE2C,CHMP7,NDUFB6,ZDHHC8,TAP1,PLXNA1,CCNB1,UTP25,KIFC1,SNUPN,DBNDD1,MAST2,CDC25B,TFG,DNMT1,SEH1L,USO1,ATG9A,AKT2,NOL8,DDX20,AURKB,MCFD2,SLC25A5,FOXRED1,MAK16,TMED10,PSMD8,EIF2D,ITGB1,RRS1,ARRB2,RTN3,HDAC2,LIME1,MAPRE1,GMFG,KIF23,PMF1,METTL3,JMY,NDUFS4,CFLAR,FKBP1A,NDUFAF6,SNX18,HDAC7,ATP6V0A2,PIKFYVE,TMED2,TERF2,DDX28,SIGMAR1,NOA1,SEPT8,PLEC,TOMM40,CYFIP2,PKM,KDM3A,PATL1,SF3A2,FAS,EPRS,NSF,PPP3R1,VCPIP1,PPP6R3,YY1,CDK2,DNMT3A,TRIP10,URB2,SUZ12,SF3B1,EIF3D,RAC1,TERF2IP,MOAP1,KDM2A,SHC1,GPX4,MRM2,CCT2,RFC3,MKLN1,TAOK1,CUL3,CDC23,GAR1,H2AFV,POLG2,CENPU,NSA2,HSPA4,MRPL55,GOLGA8A,TBL3,H2AFX,TRIM32,PDCD11,ATMIN,CSNK1D,POLQ,PKP4,TWNK,BABAM1,BLM,RAB11A,MAD2L2,PIP5K1C,PTEN,RPL17,CENPJ,PRC1,COPS7B,CREB1,IFT46,PACS2,SMC4,ZFP64,STRIP1,NEK7,WDR18,RPL8,ANAPC2,RHOT1,RPL27A,TSR2,MARK2,HGS,PRDX3,ATP5MC3,TFDP1,STX18,CCDC69,NAXE,BRWD3,BYSL,DDX52,NPHP4,PLXNC1,NOP2,ST13,NF1,UBN1,AGFG1,SIRT2,TAF6L,KIF2C,SNRPD3,MAPK14,BECN1,CUTC,EDC3,RAP1A,EIF4A3,ZNHIT6,ATG3,DPYSL2,KHDC4,NDUFB9,KIF22,RP2,NFU1,ARID4A,TIMM50,ELOF1,COPS8,FOPNL,WDR82,CHAF1A,UBTF,GEMIN5,PAF1,TIMM29,PQBP1,ATXN2L,ROCK1,COPS6,SASS6,RPS26,STARD3NL,SLC12A7,RPS15,TM9SF4,CIB1,MEF2A,BANF1,CAPZA1,ZNF335,GLTP,BCL2,KIFAP3,KNTC1,HP1BP3,SEPT7,CAND1,TSC1,NAP1L1,CDCA5,ODF2,NUP62,PITPNA,RBBP4,PDSS2,SMARCD1,MBD1,WASF2,ASH1L,IMMT,TOMM20,FAM92A,PLAGL2,NSD3,TWF2,CHD1,MEAF6,MIEF1,ANKRD28,FARSA,ANKLE1,BABAM2,SAR1A,AKAP8,APOOL,F2R,ABI1,HTRA2,FAM172A,DMAC2,WIPF1,TOR1AIP2,ERBIN,NDUFB1,PEF1,RAD54B,DAP3,CHCHD1,SCARB1,REEP4,SMURF1,PPP2R2D,CBX4,MIF,KIF3B,GOLPH3L,MRPL42,EYA1,SRGN,MRPS26,TIMM21,FBXO5,PELO,MRPL11,TTC17,GINS1,TELO2,HMGN1,NASP,ASPM,WDR81,MEN1,ATP5MF,MFN2,MAPK3,ATAD2,ATP6V1C1 |
| 1.974e-26 | -59.19 | organic cyclic compound binding | molecular function | GO:0097159 | 6166 | 1191 | 17224 | 2647 |
ZBTB10,ABCC10,LACTB2,RBM4,ZNF275,EEF2K,RPL23A,USF1,THAP4,RAD23B,ATP13A3,DNM2,UPRT,CRY2,ZNRD1,TIPARP,LRRC59,FTSJ3,ERCC1,RHOBTB3,ZNF559,NRAS,GABPA,KIF15,HNRNPF,WDHD1,MIER2,DIDO1,MCM2,RAB22A,ARF4,AHNAK,SMAD2,RAD18,RPS27A,MYO18A,RNASEL,SMAD1,ZNF75A,ANXA11,SMNDC1,PDCD4,ZNF720,HIVEP3,CLSPN,RHOC,TRIO,DHX9,RAB23,EIF2AK4,PARN,TFAP4,SMC3,RBM34,EFTUD2,MRPL21,CPSF4,PABPC1,PHKG2,NSUN4,LUC7L2,SRSF11,EIF3L,AGGF1,RBM42,FOXK1,MAPKAPK3,MTA2,SF3B6,TYW1,GTPBP4,USP10,BCLAF1,MRPL16,ELK1,EIF4H,ETS2,TYW5,ZNF830,CFAP20,ACSF2,MRPL3,RHOG,KARS,NQO1,TPX2,GLRX3,RCOR3,CPNE3,CBWD5,RBM23,AHCTF1,ZNF420,MTA1,UBA5,GMEB1,NABP1,CLCN6,SEPT11,ZNF226,GPD1L,ZC3H3,ARL5A,CGGBP1,ULK3,SEC61B,POLR2L,KAT7,IDH3A,CRNKL1,RPL38,CIRBP,E2F3,POLR2D,PFKFB3,MEF2D,RAB1A,MAT2A,KIF2A,LSM6,CENPBD1,SNRPG,PPP5C,TUBB,ZNF445,SRSF6,ZFP91,TRMT6,HABP4,IP6K2,ATP5F1B,PMVK,IFT27,RRP36,NEIL2,TUT4,SRXN1,RPA2,ZBTB45,CBWD2,HUWE1,ARF5,ARHGEF1,ZNF260,NAP1L4,ZNF710,FBXL19,GTF2H2,RPL22L1,STAU1,DDX24,LDHA,LLPH,UTP20,SLC19A1,ACOX1,AEN,THAP5,GPATCH4,YTHDC2,RBM8A,SND1,FANCI,PAPOLA,KRR1,CREM,TET3,RAB8A,GLIS2,POP7,NOC2L,EIF5,MTPN,RYBP,PLK1,RPP25,SEPT9,RAD51AP1,SNRPB,ZBED5,CDC6,PBRM1,EAF2,UTP3,LUC7L,LSG1,CHD3,ZNF367,E2F4,PRPF4,KPNA2,FAM208A,POT1,CCDC137,ZNF564,FUBP1,CTU2,PARP12,ZCCHC9,HJURP,CHCHD2,CDK13,RAB6A,ARID1B,SUB1,MLX,UBE2Q2,MBD2,SSBP3,KIF13B,XPA,ZNF746,AHCY,RBM3,NTPCR,ACSL3,LDB1,MAP4K3,ZNF761,RBM38,IRF5,BBS12,RXRB,RPL36,NLRC5,SIL1,DTD1,RUVBL2,MYO9A,BCCIP,SART1,SUCLG1,ARID2,ZNF416,RRAGC,ATP6V1B2,LYN,PCBP1,ZNF121,NRF1,PSMA6,ZNF473,ZNF302,RPAP1,TARDBP,TOP1MT,AHCYL1,STRAP,ZNF583,KDM3B,MND1,CLCN3,POLR2G,ZNF780B,RAB7A,PPIE,DCLRE1C,MRPS14,EIF3H,SUGP1,IDE,DHX16,RBL1,FASTK,STK38,UHRF2,XRCC3,H3F3A,SMAD4,RAD51D,NADSYN1,NIFK,UNK,MCM10,MTERF1,PDAP1,AGO2,GTF3A,HMGN3,ARF1,CDK11B,SCYL2,GTPBP3,POLR1B,ORC3,RNLS,RBM15B,YTHDC1,PPAN,RHOA,CSRP1,HMGN5,BTAF1,PRKDC,METTL5,ABCF2,TUFM,TOP3A,RANGAP1,PNPLA8,API5,ZFR,DDX23,RAB18,SEC23IP,TRIM26,NEK1,NEIL3,BBX,E2F1,IMPDH1,RBPJ,TAF12,NR2F2,HIPK3,IFI16,TXN,MAX,H2AFZ,PNISR,CXXC1,UBE2I,OAT,MYEF2,PARK7,GLMP,ZNF428,PA2G4,NOL11,FIZ1,RAB4A,ZNF200,TRA2B,SUCLG2,CISD2,SMARCE1,ZNF800,CDC5L,SRSF10,SRP72,ZNF524,KLF10,OSBP2,NSUN2,CBFB,RFC2,RAB2B,CLNS1A,EIF3A,PRIM1,ZMYM3,DOT1L,MAP3K4,HHEX,MKNK1,KIF18B,RPS14,LUC7L3,MRPL27,MAP4,BTF3,CCDC59,ZMAT3,NMD3,PRPF38B,RECQL,EWSR1,POLR2K,PRKAA1,GSPT2,RRM1,CYCS,PRPF39,ZNF79,ZNF518A,PDXDC1,RTKN,RPN1,CEP104,LHX8,EXOSC7,MSH2,DAPK1,MRPL40,CYC1,TNRC18,MRM3,EIF5A,PRIM2,COQ8A,USF3,ZNF574,C1orf35,RPS24,EXOSC9,ARID1A,ADRB2,FXR1,MTR,MAP2K2,CCT8,PHF6,AKAP1,HMGN2,XRCC5,PI4K2A,CAT,HSPBP1,RBMX,PIAS2,CEBPG,CDKN2A,ZNF511,TP53RK,RAB11B,RAF1,KIAA0232,CD320,DECR1,RALB,ADCY9,MRPS27,TAP2,RNASEH2A,AQR,RBM12B,CDK12,SAP30,DRAP1,VDAC2,EDF1,PKMYT1,TRIM28,SUPT16H,EIF3K,ANKZF1,ZNF282,RAD51C,HINT1,RAB24,DGCR8,CERS6,SAFB,CBWD1,ATF6,BEND3,XRCC4,DYNC1LI2,PRPF4B,MECP2,SECISBP2,HMG20A,HLA-A,JAKMIP1,MRPL54,RPL19,CARF,MSH6,RFXANK,BMS1,MACF1,GUF1,KIF11,KLF6,MYO1F,RPL32,ZHX1,DUSP11,DDX5,WDR62,TAF6,PURA,DDB1,RORB,ZBED3,POLA2,ZNF76,HMGXB3,UBE2Q1,ABCB10,BRIX1,ZNF696,SF3B2,CDC42,GOT2,RAB35,JAZF1,HADHB,RPF2,GPATCH1,TCEA1,CARM1,SRPK2,DEAF1,LARS,SNRNP200,ZCCHC10,SREK1,KMT2C,RPL37,EIF4ENIF1,NIP7,U2SURP,CRCP,BAZ1B,STK11,ZNF268,CHEK2,VPS4A,MRPL13,UBE2D3,ZCCHC8,NACA,RPL15,THRAP3,TTF1,CHKA,LYAR,CSNK1G3,POLR2I,ERLIN1,NUDT4,SUGP2,RPL6,EIF2A,SLTM,DAPK3,MASTL,NFIL3,SLC16A1,YWHAZ,EHD4,SNRNP70,TSEN15,ADNP2,TCF12,MDH2,PMS2,UCK2,SMARCA4,UCK1,ORC1,MXD1,HNRNPA2B1,RRN3,IARS,CD3EAP,NVL,KIF14,EXOSC1,CS,CYB5R1,UTP4,ZNF770,CSTF1,POU2AF1,PCGF6,ATXN1,LSM8,OGDH,MBD3,RPS9,DUS3L,HNRNPR,STAT6,ARNTL,FKBP5,MAPK1,BRD9,ABCA1,NAT14,DNAJC2,ZNF316,SHPRH,RAE1,SCYL1,MYO9B,MXD4,PIP4K2A,GFM2,KIF5B,FASTKD3,FGFR3,GRK2,PPIG,RRBP1,NABP2,DUS2,H2AFY,ANP32A,FBL,ERI3,STAT3,MICAL3,MYO5A,HEMK1,HELB,PSPC1,MIER1,ATP2C1,NADK2,RCOR1,CDK11A,TFEB,LEMD2,UPF1,ZC3H7B,KMT2B,CENPT,HRAS,TERF1,RAB14,ADD1,MRPS15,DHX8,GLUD1,PABPC4,CDK5,NEK6,NSRP1,SRSF4,PDS5B,NUP153,PCBP2,PLK3,ZNF672,AATF,MRPL43,TOPORS,SMC2,ZNF689,LIMK1,PRDX5,TFDP2,E2F2,LONP2,PFKP,SSRP1,DDX42,MRPL9,CERK,TOP2B,RAVER2,MCTS1,DDX56,EIF2S2,MCM5,ZNF326,RTCB,FOXN2,CARS2,UBE2QL1,CYFIP1,ETV3,PRRC2A,DHX29,PGS1,ZMYND11,MYBL2,RPS10,SRSF5,MPG,MATR3,ABCF1,RHOB,CYB5A,CCDC86,POLR2J,CSK,MDH1,CNOT6,ZNF207,ZNF296,SARNP,ABCA3,TRERF1,IVNS1ABP,ACTR3,CHD1L,RMI2,MYH9,CREBL2,EFL1,ZNF267,SAFB2,PRKACA,APP,KTN1,PRKD3,RAB21,SP100,ATP2A2,ZKSCAN1,UTP18,DUT,GRSF1,ZCCHC2,RBM15,ATF2,ADCY7,MAP4K4,RNPS1,WBP2,NUSAP1,DNAJA1,FKBP3,DDX17,TAF2,NT5C3B,HIPK2,RBMS1,FUS,PDXK,ZBTB11,GEN1,ZNF786,GALK1,RPS2,ANXA6,JMJD6,ETS1,ZNF92,PNO1,KRI1,ERH,SUV39H2,GATC,PPP1R8,PRDM4,DCP1A,TTLL12,HNRNPM,LDHB,PDPK1,TK1,GUK1,TNFAIP3,POLK,ZNF512,DDX39A,RPA1,ZNF180,ZNF862,KIF18A,POLE,PITX1,MAPK6,PML,LRPPRC,HMGB2,WDR76,USF2,DDX47,THOC1,GPBP1L1,MCCC1,CSNK2A1,EBNA1BP2,KCMF1,LIN9,ABL2,PCNA,ZNF639,ETV6,TRMU,XRCC2,MYBL1,CCAR1,MRPL32,ABCC5,SP3,METTL1,EXOSC6,BAZ2A,HARS,TLK1,MRPL12,EZR,BRCA1,PRKRA,RAB5B,RHEB,SEPT1,QRSL1,ACTB,DHFR2,ZNF45,SEPHS2,CTCF,RLF,CRLF3,ASXL2,RB1,MED8,TIMELESS,SLC27A4,AFF1,AHDC1,ALDH18A1,PREB,ABCC1,AACS,NQO2,UTP15,RTF1,EIF2AK1,KRAS,UBE4B,EIF4G2,ZNF174,PSMC4,SYNCRIP,PALB2,PRPS2,TBPL1,ATP5F1A,TIGD2,UGP2,FOXM1,MRPL39,SUMO2,RPL11,RAD23A,CSDE1,PDK2,ZBTB21,MDM2,DUS4L,STRBP,PDCD2,CORO1A,SAP30L,RPL29,RPL35,TIGD5,CYP20A1,NFATC2,PRPF3,KDM1B,ARL5B,USP36,RPSA,SRSF1,MRPL2,ATP1A1,CLK3,SCAP,ZNF700,MAFK,DNAJC17,ZNF436,NCOA1,FAU,LTA4H,ZNF146,CDC40,MIF4GD,CDT1,GNE,ARID5A,ARFIP2,SMC6,NKRF,CSNK1A1,RMI1,TFRC,WRNIP1,STARD9,IRF4,NDUFV1,ABCD1,DDX31,CAMK2G,ZNF202,ZMYM5,RHOT2,TPD52L2,TFE3,PGRMC1,ACADM,RPS6KC1,UBE2C,ZNF496,TAP1,YTHDF3,EIF1B,POLR3K,UTP25,KIFC1,SNUPN,CYB5RL,PARPBP,MAST2,DNMT1,NOL12,USO1,AKT2,PBK,NOL8,MKI67,DDX20,AURKB,SLC25A5,ZFAND5,MAK16,RCC1L,RBM47,EIF2D,DHTKD1,RRS1,ZNF598,HDAC2,DDX58,PPIB,HSPH1,MAPRE1,MUT,CHTF18,KIF23,METTL3,FKBP1A,MEX3C,KLF16,CTPS1,PIKFYVE,GNAI2,ANKHD1,EEF1D,TERF2,MORC3,DDX28,ZNF84,NOA1,PIP4K2C,SEPT8,FAM133B,RIT1,PLEC,CYFIP2,PKM,KDM3A,PATL1,SF3A2,ADSS,EPRS,ZNF777,NSF,ZFP92,QARS,DCK,CSNK1G1,ACLY,TCOF1,MAP3K5,YY1,CDK2,NRBP1,ZC3HAV1,DNMT3A,ZBTB37,CAST,SUZ12,SF3B1,RPS6KA1,EIF3D,RAC1,OLA1,SDE2,SDHA,PAIP2,TERF2IP,PHC2,FLAD1,CRKL,APLP2,ZNF75D,KDM2A,UCHL5,CDKN2AIP,CCT2,RFC3,ATP13A1,HMGN4,ERF,TAOK1,SLBP,GALK2,GAR1,H2AFV,POLG2,DHX57,NSA2,VEZF1,HSPA4,JAK1,GUCY1B1,FAAP100,TBL3,STAT1,H2AFX,TRIM32,PDCD11,ATMIN,CSNK1D,RHEBL1,POLQ,POU3F2,NCOR2,TWNK,TCF3,BRAP,MYNN,BLM,SPR,RAB11A,FOXO3,PIP5K1C,GTF2F1,RBM17,RPL17,UPF2,CREB1,MAP3K14,UBE2M,NCOA2,SMC4,TSHZ1,ZFP64,TRIR,NEK7,RPL8,PARP4,ILF3,TBRG4,RHOT1,RPL27A,MARK2,POLR2A,PRDX1,GNA12,FBXO21,NUCB1,C1orf131,TTLL4,HNRNPH3,MFAP1,TFDP1,KHSRP,NAXE,ASNA1,CPEB2,BYSL,DDX52,IER2,UBE2E2,ST13,NOP2,HNRNPAB,UBN1,FLYWCH2,ALKBH5,ZNF107,UBE2Z,SIRT2,AGFG1,TAF6L,KIF2C,SNRPD3,FKBP2,MAPK14,SNAPC4,EDC3,MBD4,ZNF804A,CMSS1,RAP1A,EIF4A3,METTL14,PHTF1,KHDC4,ZBTB22,KIF22,RP2,OGG1,ARID4A,TIMM50,FYTTD1,TDP1,SOX4,STK17B,DHX15,UBTF,CXXC4,GEMIN5,IARS2,PQBP1,ATXN2L,ROCK1,RPS26,PSMC1,STARD3NL,RPS15,ZNF768,TIA1,MEF2A,SRRT,NFATC3,ZNF449,BANF1,ZNF335,YBX1,BCL2,ACAD8,N4BP2,HP1BP3,ZNF189,CIC,PSMA1,SEPT7,GNAS,NAP1L1,RBM25,ZFP90,RBBP4,HNRNPDL,ZBTB24,MBD1,NOP9,MMACHC,IMMT,ASH1L,CHERP,HNRNPUL2,PLAGL2,IRF3,CHKB,TWF2,CHD1,PAIP1,MIEF1,FARSA,ANKLE1,SAR1A,AKAP8,CHTOP,SCYL3,ACSL5,FAM172A,CGAS,ZNF500,BUD13,PEF1,GFER,EIF3G,RAD54B,ZNF317,DAP3,CHCHD1,AKNA,CBX4,KIF3B,MRPL42,EYA1,TOR3A,MRPS26,DBF4,KLF13,GART,BRD7,MRPL11,SAMD4B,PAQR6,TELO2,GTF3C6,CSNK1G2,HMGN1,PRKAR1B,MEN1,ZNF407,SNRPA,TARS,HSPA1B,MFN2,MAPK3,ATAD2,OSBPL8,ZRANB2,MBD6,SRSF3,IDH3B,TYW1B |
| 2.030e-26 | -59.16 | cellular macromolecule localization | biological process | GO:0070727 | 1396 | 358 | 17256 | 2622 |
TMED7,RAB14,TXN,NUP188,TSC2,AP3M2,SYNRG,RIC1,PARK7,MIS12,RPL23A,CDK5,NAPG,SNUPN,RABGAP1L,RAB4A,SRSF4,AP1M1,AP2B1,NUP153,SEH1L,SRP72,USO1,ATG9A,AKT2,NOL8,MRNIP,TOPORS,NUTF2,AURKB,ICMT,RAB22A,RAB2B,ARF4,HHEX,TMED10,RPS27A,RPS14,EIF2D,VIPAS39,RRS1,SLF1,NMD3,LONP2,AAAS,NXT2,MAPRE1,GGA1,SEC61G,DHX9,RAB23,TMED3,SUPT7L,VPS25,COPG2,LMNA,SPAG5,NPLOC4,COPB2,ATG4A,RTKN,TMEM250,FBXO7,TNPO3,PIKFYVE,CPSF4,SYTL3,NUP85,TMED2,TERF2,MORC3,SRSF11,NAGPA,EIF5A,TIMM8B,GCC2,RPS10,RPS24,SEPT8,SSR2,SRSF5,MTX1,TOMM40,PTTG1IP,RHOB,XRCC5,DERL1,SEC31A,SCARB2,FNTA,KPNA1,NSF,FAM83D,PPP3R1,WIPI2,SGF29,NUP58,EXOC3,NDC1,SARNP,SYS1,RAB11B,ANK3,VTI1A,TBC1D13,AP1B1,STAM,TERF2IP,MOAP1,RAB21,SP100,TBC1D22A,TBC1D14,NUP107,SEPT11,TNPO2,ANKRD13C,ZC3H3,ARL5A,SNX8,SEC61B,INTS13,RNPS1,POLR2D,RPL38,SLBP,DNAJA1,RAB1A,AP4E1,PEX5,CHMP4A,HSPA4,SEC61A1,VPS26B,RAB24,CCDC14,RPLP1,SEL1L,PITRM1,CSNK1D,RPS2,MZT1,SRSF6,FLOT1,TRAK1,SPDL1,IFT27,RAB11A,WRB,RPA2,RPL17,AXIN2,DCP1A,RPL19,UPF2,MTX2,PACS2,PPP3CA,TNFAIP3,DENND4C,RPL8,PACS1,RAB3IP,DDX39A,MACF1,RPL27A,SH3GLB1,RPA1,HGS,RPL32,STX18,PML,SSNA1,CD81,YWHAH,WDR45B,IPO4,VPS29,SNAPIN,POLA2,MTX3,COPA,THOC1,AGRN,RBM8A,SNX15,ALKBH5,AGFG1,BECN1,SEC16A,SSR1,RAB8A,NUP210,TIMM23,EIF4A3,AP3S2,RAB35,ATG3,ZFYVE27,RPF2,CARM1,TIMM50,PTPRK,CDC37,PLK1,FYTTD1,LARS,SEPT9,MIOS,TLK1,EZR,ANLN,RAB5B,STX16,OPTN,RPL37,PAF1,TRAM2,SEPT1,TBC1D17,TIMM13,GRIPAP1,TIMM29,MIA2,KPNA2,VPS4A,ROCK1,DVL1,CLU,RPS26,POT1,C2CD5,RPS15,TBC1D12,PHB2,NKD2,LAMTOR3,TIA1,RPL15,CTCF,RAB6A,XPO7,RAPGEF6,RHBDD1,NUP205,PRPF18,RB1,KIF13B,XPA,PPIL2,ARL6IP1,YBX1,GLE1,MCPH1,LRSAM1,PREB,KDELR1,RPL6,SYVN1,SEPT7,ZDHHC3,RPL36,TSC1,PCM1,GOLGA4,LAMTOR4,EXOC4,ZDHHC7,SIL1,NUP62,CTSA,RUVBL2,SNX27,TOMM20,RPLP2,TOR1AIP1,RRAGC,TWF2,RPAIN,BCAP31,RPL11,HNRNPA2B1,ANKLE1,MDM2,SAR1A,BCAP29,AHCYL1,CLTB,CHTOP,LMAN1,DVL2,CHP1,PRPF19,RPL29,NXT1,RPL35,RAB7A,TOR1AIP2,NUP155,BICD2,ERBIN,ARL5B,TOLLIP,RPS9,RPSA,SRSF1,SURF4,VPS26C,TIMM17A,TULP3,ARNTL,AP1S1,CHMP4B,SMURF1,AP2S1,TSPAN5,PARD3,TMEM33,CDC40,GOLPH3L,KLHL21,RAE1,DCTN2,SRGN,NUP54,VPS45,ARFIP2,TIMM21,GGA2,AP3S1,SEC24C,NABP2,ARHGEF2,H2AFY,ATG13,STAT3,MYO5A,TGFB1,ZDHHC18,SNX2,RANGAP1,SYMPK,MFN2,LEMD2,RAB18,SEC23IP,UPF1,ATP6V1D,PDCD6,KPNA4,GOLGA7,OSBPL8,FAM126A,CENPT,SPCS3,SRSF3,CHMP7,SLF2 |
| 2.355e-26 | -59.01 | WEI_MYCN_TARGETS_WITH_E_BOX | MSigDB lists | WEI_MYCN_TARGETS_WITH_E_BOX | 731 | 221 | 17377 | 2626 |
SRM,SKA3,NOP2,MRPS15,GNPDA1,XIAP,LACTB2,OAT,BRIX1,SLC20A1,CUTC,POLR3K,MRPL19,ANKRD39,FBXO22,SSR1,PAPOLA,CREM,CALM2,PA2G4,PSMD1,NOL11,CDC42,ZNF639,SIVA1,IMPAD1,POP7,ATP13A3,CISD2,EIF5,MCMBP,DNMT1,SEH1L,TIMM50,COPS8,CCDC138,NSUN2,PSMG1,RRM2,DDX20,CDC6,AURKB,SMC2,ANLN,CBFB,ODC1,LSG1,DPYSL3,DOT1L,GEMIN5,HSPB11,PPM1G,MRPL27,WDR4,C1orf109,PTPN7,QRSL1,CLN3,CCDC59,ATP6V0E1,SMNDC1,B4GALT2,SVIP,CCDC137,NXT2,STARD3NL,HSPH1,C9orf78,MAPRE1,MRPS2,DHX9,SLC35B1,HAUS2,LYAR,RB1,MED10,MSH2,TNPO3,SLC12A2,LPCAT1,TRAFD1,PRIM2,MAPKAPK3,SIGMAR1,WDR1,NSDHL,AMD1,EXOSC9,MAP7D1,C9orf40,ICAM2,CCT8,DAPK3,AKAP1,MASTL,SLCO4A1,SYNCRIP,UAP1,CSK,CDCA5,ACLY,FAM83D,SLC16A1,EHD4,SNRNP70,PTDSS1,EGLN1,ZNF511,BCCIP,CORO7,SUCLG1,URB2,MRPL39,UCK2,STARD7,TMEM97,KLHL18,SMARCA4,ADPGK,ZNF267,LYN,GLRX3,COMMD8,KTN1,USP5,NUDT19,MRPL50,FLAD1,ATP6V0B,AHCTF1,ATP2A2,CD3EAP,UTP18,UCHL5,NUP107,CLN6,ARL5A,SAP30,PPIF,CCT2,MND1,RFC3,CDC123,E2F3,NLN,NUP155,RAD54B,RAD51C,IDE,HSPA4,DUS3L,SURF4,CERS6,LSM6,TIMM17A,CHCHD1,CANT1,ANP32E,SCARB1,GEN1,XRCC4,LRP8,PDCD2L,SLC25A39,TUBB,GCLM,MZT1,MCM10,DEPDC1,RRP15,MRPL42,C1orf112,TOR3A,TRMT6,SMC6,SDF2L1,CHAC2,GGA2,BLM,TFRC,PNO1,EBP,SRXN1,RFWD3,GTPBP3,GOLM1,PSMD2,HOMER1,AHSA1,GEMIN6,UPF2,POLR1B,UBE3B,LDLRAD3,MYO5A,TMX1,HNRNPM,MOB4,MLEC,TMEM126B,ABCF2,SCFD2,LLPH,SYMPK,HSPA1B,HGS,KPNA4,PDCD6,C1orf131,ATAD2,BIRC5,ZNF330,DBI,C4orf46,SPCS3,ATP6V1C1,YWHAH,HRAS,THAP5,SSSCA1,BYSL |
| 2.567e-26 | -58.92 | PATIL_LIVER_CANCER | MSigDB lists | PATIL_LIVER_CANCER | 690 | 212 | 17377 | 2626 |
CCDC93,PLXNC1,AGRN,AP3M2,UBE2Q1,PTP4A3,ABCB10,SLC29A1,BCAT2,CDKN2C,DLG5,ABL2,PCNA,IMPAD1,PIK3R2,MECR,CDC25B,TCEA1,SLC26A2,TACC3,PLK1,BAK1,RHOBTB3,OSBP2,APH1A,PBK,SNRPB,RRM2,CDC6,DIDO1,PRPSAP1,USP21,PLEKHF2,ASF1B,CHAF1A,PRIM1,MID1IP1,NRM,U2SURP,OGT,KPNA2,CLN3,E2F2,RTN3,CAPN1,SVIP,PARP12,HJURP,KIAA0100,POLR2K,RHOC,TRIO,CUTA,CENPF,RRM1,KIF23,FAM136A,XPO7,NUP205,YY1AP1,DTL,INTS7,MCM5,RBM3,KNTC1,CYC1,PIK3IP1,ALDH18A1,LPCAT1,TMED2,PRIM2,RB1CC1,AACS,RDH10,MYBL2,MTX1,ABCF1,HMGN2,PTPRF,NAP1L1,DCK,CDCA5,ACLY,DTD1,CTSA,YWHAZ,TCOF1,TOB1,TMEM106C,WASF2,SNX27,ANKRD27,DNMT3A,TOMM20,CKLF,NQO1,PTTG1,UCK2,LAGE3,TMEM97,OLA1,TPX2,SMARCA4,NUF2,TBC1D13,STMN1,ANKIB1,BCAP31,KIAA1147,RAD23A,HNRNPA2B1,FLAD1,CCNA2,SHC1,IARS,DUS4L,ZKSCAN1,UCHL5,TBC1D14,CS,MAVS,CABLES2,TP53BP2,TMEM136,RBM12B,SAP30L,DVL2,MOSPD1,CLPTM1,CPNE1,ERMP1,MAP4K4,SLC26A6,E2F3,HTATIP2,NUSAP1,NUP155,BOLA1,FAM72B,PKMYT1,MEF2D,TRIM28,RPSA,SUPT16H,PPP2R5A,DDOST,CCDC14,UBXN2B,FASTK,HIPK2,CEP55,H2AFX,AP1S1,XRCC3,SLC22A23,B4GALT3,TSPAN5,TUBB,GCLM,MZT1,SCAMP3,MRPL42,SESTD1,SCYL1,CDCA8,KLF13,GMCL1,AKT1S1,MXD4,AP3S1,IL21R,RAB11A,RMI1,POFUT1,XPR1,SAC3D1,SRXN1,SLC1A4,CENPJ,UBE3B,CENPM,ERI3,ORC3,UBE2M,NCOA2,CAMK2G,SMC4,RBM15B,JMJD4,ELOVL5,TK1,FAM49B,KAT2A,PRKDC,ILF3,CCDC34,ADSL,NDRG3,KIF11,NEU1,PRDX1,GNA12,HGS,CDKN2AIPNL,ATAD2,ELMO1,BBX,E2F1,PLOD3,TAF6,UBE2C,ESPL1 |
| 4.877e-26 | -58.28 | GRADE_COLON_CANCER_UP | MSigDB lists | GRADE_COLON_CANCER_UP | 800 | 235 | 17377 | 2626 |
MIB2,SKA3,H2AFZ,TXN,PRKCSH,ZNF107,PTP4A3,NENF,PLXNA1,SND1,CCNL2,FKBP2,SNRPD3,MIEN1,KCMF1,PABPC4,ANKRD39,SSR1,PAPOLA,PCNA,INTS1,ATP13A3,TXLNA,NOC2L,AP1M1,ECD,TECR,MGAT5,PCBP2,CARM1,SRP72,ORAI2,EXOSC6,DPM1,RBX1,SNRPB,MRPL12,RRM2,NUTF2,SOX4,STX16,ODC1,RAB22A,BRMS1,ALG3,SEPT1,PSMD8,RPS14,PRDX5,U2SURP,BCL7C,OGT,CRCP,ST3GAL2,MRPL13,ZNF598,OAZ1,UBE2D3,PPIB,MRPL9,KIAA0100,DLGAP4,DHX9,CHCHD2,NDUFA4,PMF1,TMEM165,PDXDC1,FBRS,MCTS1,RTKN,RPN1,SUB1,VMP1,INTS7,ATIC,MCM5,RBM34,MEGF8,BANF1,YBX1,RBM3,SLC12A2,PPA1,EEF1D,EIF5A,POLR2I,PIGT,TSTA3,PSMA1,RPS24,SSR2,TOMM40,MPG,EIF4H,SF3A2,ZDHHC3,CCT8,PSMB3,CAND1,PSMC4,RPL36,TSC1,EPRS,SLCO4A1,HSPBP1,PALB2,SYNCRIP,ERGIC3,SMPD4,MZT2B,ZNF511,WASF2,ZNF207,PPP1R37,RPLP2,DYNLL1,MDH2,EIF3D,ACTR3,OLA1,MYH9,POMP,C19orf48,PCBP1,GNB2,BCAP31,C2orf68,RPL11,RAD23A,USP5,HNRNPA2B1,NSFL1C,TALDO1,GPX4,ATP6V1G1,DCTN1,CPNE1,PPIF,CCT2,RPL29,RPL35,SEC61B,CDC123,PSMB7,RPL38,ABHD11,NDUFA7,EIF3G,TRIM28,RPS9,GIGYF1,EIF3H,SRSF1,NSA2,EIF3K,SEC61A1,DSN1,DDOST,VPS26B,MAFK,NSMCE2,STAT6,HAGHL,CBWD1,PDXK,SNRPG,CENPBD1,TMEM101,SLC25A39,PDCD2L,MIF,BCL2L12,C19orf53,PDAP1,SRSF6,TCF3,TKT,GTF3A,SLC12A9,POFUT1,WRNIP1,RBM17,ERH,HOMER1,NDUFV1,ADD3,NDUFB4,ARHGEF1,AXIN2,ANP32A,H2AFY,UPF2,RPL19,TAGLN2,FBL,HNRNPM,LYPLA2,S100A6,AMPD2,PPP3CA,STAU1,HMGN1,MLEC,GUK1,NET1,PRKDC,BTAF1,ILF3,RPL8,PARP4,JTB,TUFM,LDHA,BMS1,RPL27A,DDX39A,API5,TARS,NUCB1,HGS,PDCD6,ATAD2,RPL32,PITX1,KHSRP,ASNA1,HMGB2,SSNA1,PSAP,PLOD3,UBE2C,USF2,YWHAH,ESYT2 |
| 7.306e-26 | -57.88 | LEE_BMP2_TARGETS_DN | MSigDB lists | LEE_BMP2_TARGETS_DN | 821 | 239 | 17377 | 2626 |
SRM,SKA3,HNRNPAB,NOP2,YTHDC2,MOGS,USP39,EBNA1BP2,AGFG1,BRIX1,SLC20A1,KCMF1,POLR3K,SSR1,KRR1,ANKRD26,PA2G4,NOL11,TIMM23,DNAAF2,RAD23B,NOC2L,AKR1B1,RPF2,NUP153,LRRC59,DNMT1,SEH1L,SRSF10,COPS8,RAD51AP1,NOL8,NSUN2,GMFB,RRM2,DDX20,WDHD1,CDC6,BRCA1,NUTF2,MCM2,LUC7L,FOXRED1,ODC1,MAK16,ASF1B,CLNS1A,DOT1L,GEMIN5,ALG3,NIP7,LIMK1,WDR4,QRSL1,KPNA2,RRS1,NMD3,HDAC2,FUBP1,HSPH1,RECQL,SCOC,CLSPN,MRPS2,RRM1,CYCS,DNAJB1,FAM136A,QSOX2,CDC73,NUP205,DTL,LYAR,DDX56,PDXP,NUS1,EIF2S2,SMC3,MED8,MCM5,ATIC,FOXN2,RBM3,CYC1,GEMIN4,NUP85,PPA1,HDHD2,IFRD1,NOA1,DHX29,NQO2,AMD1,UTP15,GTPBP4,USP10,RPS24,DCTD,NFATC2IP,C9orf40,MATR3,CCT8,TWISTNB,MTHFD2,KPNA1,SYNCRIP,CCDC86,DCK,RBMX,SLC16A1,PRMT7,TCOF1,RUVBL2,NAA20,BCCIP,MMACHC,TOMM20,URB2,UCK2,TMEM97,ADPGK,CHD1,ARL6IP6,MRPL50,TMEM69,RRN3,IARS,DUS4L,NVL,UTP18,UCHL5,PIN1,DUT,EXOSC1,NUP107,TARDBP,LMAN1,GPD1L,STRAP,HTRA2,PPIF,FAM118B,COQ10B,IDH3A,PCGF6,E2F3,RNPS1,CUL3,NLN,NUP155,GSTCD,GAR1,RPS9,FKBP3,MAT2A,SRSF1,TAF2,HSPA4,JAK1,LSM6,TIMM17A,TBL3,RWDD4,FKBP5,ANP32E,BEND3,PDCD11,USP53,TMEM33,PRPF4B,DNAJC2,MCM10,RRP15,C1orf112,B4GALT5,CDT1,TRMT6,DBF4,NUP54,JMJD6,SECISBP2,NKRF,SDF2L1,WDR5,BLM,TFRC,PNO1,RPA2,GART,CTNNBL1,SUV39H2,PPP1R8,AHSA1,FUT8,TANK,ZDHHC13,NAA50,GEMIN6,POLR1B,ST8SIA2,MSH6,TMX1,GINS1,PPAN,TXNL1,PHF20L1,MLEC,NASP,HMGN5,TIMMDC1,PSPC1,BTAF1,WDR18,LDHA,BORA,DDX39A,PDE3B,TSR2,RPA1,UTP20,SLC19A1,KPNA4,SEC23IP,C1orf131,ATAD2,PLAA,TTLL4,PFDN4,MAPK6,TFDP1,LRPPRC,AEN,LY75,SRSF3,WDR76,ZMIZ1,PGAM1,SSSCA1,BYSL |
| 8.065e-26 | -57.78 | RNA splicing, via transesterification reactions | biological process | GO:0000375 | 285 | 116 | 17256 | 2622 |
SART1,CHERP,XAB2,SF3B1,RBM8A,DHX8,USP39,SNRPD3,PCBP1,PAPOLA,SF3B2,HNRNPA2B1,SNUPN,EIF4A3,METTL14,SRSF4,GPATCH1,KHDC4,TRA2B,AQR,RBM15,STRAP,CCAR1,PCBP2,CSTF1,SRPK2,PRPF19,SRSF10,CDC5L,SNRNP200,POLR2L,POLR2G,SNRPB,PPIE,SMU1,CRNKL1,HNRNPF,POLR2D,RNPS1,LSM8,DDX20,PRPF3,BUD13,TXNL4A,LUC7L,CLNS1A,DHX15,SRSF1,DDX17,SUGP1,GEMIN5,DHX16,HNRNPR,LSM6,LUC7L3,U2SURP,PQBP1,PRPF4,FUS,SNRPG,SMNDC1,GEMIN7,DDX42,CWC25,PRPF4B,CDC40,LIME1,ZCCHC8,POLR2K,SRSF6,DHX9,CDK13,PRPF39,PDCD7,METTL3,SRRT,PRPF18,GTF2F1,RAVER2,RBM17,SNRNP25,DNAJC8,CTNNBL1,CWC27,EFTUD2,BUD31,GEMIN6,YBX1,GEMIN4,CPSF4,PABPC1,LUC7L2,HNRNPM,RBM15B,SRSF11,YTHDC1,POLR2I,PSPC1,SF3B6,PPWD1,SRSF5,DDX39A,SYMPK,SF3A2,SNRPA,POLR2A,DDX23,SYNCRIP,POLR2J,RBMX,HNRNPH3,KHSRP,PRMT7,DDX5,SRSF3,SNRNP70 |
| 8.137e-26 | -57.77 | SCHLOSSER_SERUM_RESPONSE_DN | MSigDB lists | SCHLOSSER_SERUM_RESPONSE_DN | 668 | 206 | 17377 | 2626 |
H2AFZ,PLXNC1,KDM4A,ADAM10,HEXB,ABCB10,MAP1LC3B,BECN1,MBD4,CALM2,RAP1A,PSMD1,RABGAP1L,IL6ST,RAD23B,PDS5B,TRA2B,TAF5L,RP2,TCEA1,SPTSSA,PLCL2,EIF5,SMARCE1,ARID4A,PTPRK,RYBP,COPS8,SGCE,USO1,SNRNP200,BAZ2A,GMFB,UTP3,MCFD2,SLC25A5,ZFAND5,KRIT1,HSPB11,STT3A,TPP2,OGT,SMAD1,E2F2,FAM208A,SMNDC1,NXT2,GMFG,PPP1R12A,PPP1R2,SEC61G,DHX9,MEF2A,TOP2B,SLC35B1,PRPF18,NDUFS4,LRRC14,RB1,SUB1,EIF2S2,MEGF8,RBM34,MBD2,XPA,CAPZA1,MSH2,KIFAP3,PIKFYVE,TMED2,MORC3,FDFT1,NAGPA,SRSF11,PRIM2,CREG1,RB1CC1,ZMYND11,PSMA1,BCLAF1,SRSF5,ICAM2,GOSR1,EIF4H,XRCC5,CAT,NAP1L1,SERTAD2,GOLGA4,ETS2,POLR2J,DCK,COX7A2L,MDH1,MAP3K5,RBBP4,TOB1,TCF12,ZNF207,NDUFA5,UBR2,CAST,SF3B1,SUZ12,TOR1AIP1,STARD7,NIPA2,EXT2,CPNE3,KTN1,PAIP1,ANKRD28,HNRNPA2B1,SEC11A,RAB21,DECR1,SP100,ATP2A2,PPP6C,SOCS6,MRPS27,RPN2,TP53BP2,MINPP1,ATF2,ABI1,STRAP,ATP6V1G1,POU2AF1,SEC61B,HMGN4,EID1,PGGT1B,CDC123,GLO1,CHMP2B,RAB1A,H2AFV,EIF3H,NSA2,DAP3,HSPA4,HNRNPR,LSM6,HPS5,STAT1,WDR7,ANP32E,SNRPG,COIL,SLC30A9,CDC40,PKP4,MANBA,TCF3,GNE,FAM76A,HMGN3,LANCL1,FAM8A1,IRF4,ERH,ADD3,CLIC4,PDCD10,NDUFA2,PPP1R8,PPIG,PTPN11,ANP32A,UPF2,SLC35A1,NCOA2,MSH6,YTHDC1,ELOVL5,PPP3CA,HMGN1,ADAM17,SNX2,NEK7,ABCF2,RABIF,PPWD1,SH3GLB1,PRDX1,ECH1,CBX3,PDCD6,ELMO1,PRDX3,TFE3,PARG,FAM3C,CCDC69,MEGF9,LY75,DUSP11,DDX5,MRFAP1L1,ACADM,ATP6V1C1,IGBP1,TERF1,PURA,IFI16 |
| 8.148e-26 | -57.77 | biosynthetic process | biological process | GO:0009058 | 4865 | 966 | 17256 | 2622 |
RAB14,ZBTB10,KDM4A,MRPS15,PIGQ,HEXB,AGPAT1,GLUD1,CCNL2,EDRF1,RBM4,ZNF275,PABPC4,EEF2K,RPL23A,USF1,CIPC,SRSF4,MECR,UPRT,CRY2,ECD,ZNRD1,MGAT5,MRPL57,PGAP2,ZNF672,ZNF559,TMEM115,GABPA,MRPL43,WDHD1,MIER2,TOPORS,DIDO1,MCM2,GINS4,STOML2,BRMS1,SMAD2,RPS27A,ZNF689,OGT,MLYCD,VIPAS39,ST3GAL2,TFDP2,SMAD1,E2F2,CHPF2,ZNF75A,OAZ1,PFKP,SLC25A33,SSRP1,HIVEP3,MRPL9,CLSPN,MRPS2,DHX9,EZH1,CDC73,MCTS1,ATG4A,TFAP4,PDXP,EIF2S2,INTS7,MCM5,EFTUD2,ZNF326,FOXN2,MRPL21,CPSF4,PABPC1,PHKG2,PPA1,CARS2,SRSF11,NAGPA,EIF3L,ETV3,FOXK1,RB1CC1,DHX29,ZMYND11,PGS1,MAN1B1,RPS10,MYBL2,USP10,BCLAF1,MRPL16,SRSF5,CBFA2T2,ELK1,EIF4H,ABCF1,POLR2J,ETS2,SETD3,TYW5,MDH1,CNOT6,WIPI2,ZNF830,PLPP6,HEXA,SGF29,MRPL3,ZNF296,KARS,SARNP,TRERF1,NQO1,IVNS1ABP,PTTG1,STARD7,RMI2,CREBL2,RXYLT1,ZNF267,SLC35B2,INO80E,EFL1,SAFB2,RCOR3,LCLAT1,TCF19,CPNE3,PRKD3,ZNF420,SP100,ZKSCAN1,MTA1,DUT,GMEB1,NABP1,INTS12,ZNF226,ATF2,GPD1L,RPRD1B,CGGBP1,PDCL3,ADCY7,CPNE1,POLR2L,EID1,KAT7,INTS13,WBP2,RPL38,POLR2D,RNPS1,E2F3,ATP6V0A1,NDUFA7,MEF2D,TAZ,MAT2A,DDX17,TAF2,CHCHD3,ALDH3B1,HIPK2,RPLP1,RBMS1,MBOAT1,PDXK,SNRPG,PPP5C,ZBTB11,COMMD10,GALK1,ZNF786,RPS2,ZNF445,SRSF6,HABP4,TRAK1,JMJD6,ATP5F1B,IP6K2,WDR5,ETS1,PMVK,NEXMIF,ZNF92,NEIL2,RPA2,ZBTB45,ERH,GATC,COQ4,SUV39H2,PPP1R8,PRDM4,ZNF260,LTN1,ST8SIA2,ZNF710,GTF2H2,RPL22L1,MED22,IMPA2,PDPK1,TK1,GUK1,POLK,ZNF512,LDHA,MRPS10,MTMR12,DDX39A,PDE3B,RPA1,ZNF180,ZNF862,KEAP1,MAGT1,POLE,PITX1,DBI,LRPPRC,PML,HMGB2,PARP10,USF2,WDR45B,THAP5,SRM,COX15,AGRN,THOC1,GPBP1L1,GNPDA1,RBM8A,CSNK2A1,SND1,CDIPT,RUFY1,BIRC2,PAPOLA,CREM,LIN9,TET3,PCNA,GLIS2,ZNF639,INTS1,ETV6,PIK3R2,SLC44A1,XRCC2,NOC2L,PPCDC,EIF5,MCMBP,MYBL1,MRPL32,CCAR1,ABCC5,RYBP,SP3,HARS,BAZ2A,RAD51AP1,SNRPB,MRPL12,CDC6,PBRM1,EAF2,BRCA1,KRTCAP2,ODC1,USP21,ALG3,TRAM2,AGPAT2,TONSL,CHD3,ZNF367,E2F4,QRSL1,DVL1,DHFR2,ZNF45,BEND6,FAM208A,NUDT11,POT1,ZNF564,FUBP1,SEPHS2,ZCCHC9,PHB2,CENPF,SDC2,CTCF,CHCHD2,CDK13,B4GALT4,RLF,ASXL2,CNOT11,RSAD1,ARID1B,C1GALT1,SUB1,RB1,MLX,NUS1,MED8,MBD2,SSBP3,ZNF746,CTR9,TIMELESS,MDFIC,AHCY,ICE2,MRPL48,MAML1,ALDH18A1,PREB,ABHD2,AACS,NSDHL,ACSL3,LDB1,AMD1,UTP15,RTF1,ZNF761,LY6E,EIF4G2,ZDHHC3,NMT2,IRF5,ZNF174,RXRB,RPL36,MBIP,GALNT2,PALB2,PRPS2,TBPL1,ZDHHC7,PRMT7,DTD1,RUVBL2,ATP5F1A,GLT8D1,CYLD,TRAF7,RPLP2,UGP2,SUCLG1,ARID2,FOXM1,MRPL39,DYNLL1,XAB2,SLC2A1,ZNF416,RRAGC,GGPS1,COMMD8,RPAIN,ZNF121,RPL11,MRPL50,ZBTB21,NRF1,ZNF473,KMT5C,ZNF302,MRPL34,RPAP1,TARDBP,LMAN1,TOP1MT,SAP30L,ZNF583,DVL2,PRPF19,KDM3B,RPL29,RPL35,POLR2G,ZNF780B,PPT1,COQ10B,BTG2,CPOX,MTMR6,NFATC2,KDM1B,MRPS14,EIF3H,RPSA,SRSF1,MRPL2,ZNF700,RBL1,MAFK,ZNF436,DNAJC17,XRCC3,NCOA1,LTA4H,SLC25A39,SMAD4,RAD51D,INTS2,SLC30A9,CTDP1,NADSYN1,NIFK,MCM10,CDC40,MTERF1,CDT1,GNE,AGO2,ARID5A,GTF3A,NKRF,ARF1,CHAC2,PAGR1,RMI1,WRNIP1,GSTK1,IRF4,SS18L1,PTGES3,POLR1B,ORC3,RNLS,RBM15B,CNTN5,RPRD1A,HMGN5,ZNF202,ZMYM5,TUFM,TOP3A,PNPLA8,PCGF1,HAGH,GOLGA7,BIRC5,L3MBTL3,TFE3,CDCA7L,BBX,E2F1,IMPDH1,RBPJ,TAF12,ACADM,NR2F2,PGAM1,HIPK3,IFI16,TXN,ZNF496,MAX,PPCS,GXYLT1,ZDHHC8,CXXC1,NANS,GYG1,CCNB1,OAT,EIF1B,COMMD6,POLR3K,MYEF2,PARK7,PA2G4,NOL11,FIZ1,RAB4A,ZNF200,TAF5L,SLC26A2,SPTSSA,DNMT1,ZNF800,CDC5L,ZNF524,KLF10,AKT2,ELOA,USP22,GALNT7,AMDHD2,MCFD2,CBFB,RFC2,EIF3A,PRIM1,IWS1,HHEX,BRD2,STT3A,RPS14,MRPL27,EIF2D,DHTKD1,BTF3,ARRB2,ZNF598,CCDC59,HDAC2,B4GALT2,PTOV1,COX5B,EWSR1,DHPS,POLR2K,CHTF18,PRKAA1,GSPT2,RRM1,B4GALT1,PMF1,NOTCH2,SUPT7L,ZNF79,ZNF518A,PSEN1,TMEM165,VPS25,YY1AP1,NPLOC4,CNOT3,NDUFAF6,RPN1,LHX8,KLF16,HDAC7,ATIC,DAD1,BDH1,CTPS1,PIGG,ATP6V0A2,MRPL40,CYC1,PCYT2,PIKFYVE,LPCAT1,EEF1D,TERF2,FDFT1,EIF5A,PHF10,ZNF84,PIGT,PRIM2,ELL2,COQ8A,NOA1,RDH10,MFNG,PIP4K2C,ZNF574,RPS24,DCTD,ARID1A,PKM,KDM3A,MTR,TWISTNB,PHF6,XRCC5,PI4K2A,ADSS,EPRS,ZNF777,SERTAD2,GOLGA2,ZFP92,RBMX,QARS,DCK,MED15,ACLY,PIAS2,CEBPG,LPCAT4,SAMD8,SMPD4,GPI,YY1,RNF14,CDK2,NRBP1,NUDT3,ZNF511,ATXN3,RWDD1,ZBTB37,SUZ12,EIF3D,UROD,ADPGK,SDE2,TERF2IP,SPINDOC,FLAD1,ZNF75D,KDM2A,MTMR4,UCHL5,LPIN2,ADCY9,MRPS27,RNASEH2A,TALDO1,CDK12,SAP30,BRD4,RFC3,ERF,DRAP1,SLBP,ELP4,EDF1,POLG2,GAR1,SERP1,TRIM28,CENPU,PRDM11,SUPT16H,EIF3K,VEZF1,ZNF282,RAD51C,MRPL55,DDOST,HINT1,CERS6,SAFB,GUCY1B1,STAT1,FTSJ1,PPA2,ATF6,BEND3,B4GALT3,EYA2,ATMIN,POLQ,POU3F2,NCOR2,DEPDC1,B4GALT5,TWNK,MECP2,MRI1,TCF3,TKT,SLC25A12,AGPAT3,ARGLU1,SECISBP2,MYNN,SDF2L1,BLM,SPR,POFUT1,HMG20A,FOXO3,MAD2L2,PIP5K1C,WWP2,GTF2F1,EBP,RFWD3,MAT2B,CCNK,RPL17,ELP5,PTEN,FUT8,PTPN11,MRPL54,RPL19,CARF,CITED2,CNOT6L,CREB1,OSTC,NCOA2,TSHZ1,ZFP64,KAT2A,WDR18,ILF3,RPL8,RFXANK,ADSL,RPL27A,COMMD4,KLF6,GUF1,POLR2A,CBX3,RPL32,ATP5MC3,ZHX1,TFDP1,OAZ2,NAXE,KHSRP,DDX5,TAF6,CPEB2,PURA,RORB,ADA2,POLA2,CCNC,ZNF76,PTMS,PIGM,IER2,KMT2E,PHRF1,MOGS,DNAJC24,ZNF107,TAF6L,SIRT2,SNRPD3,COMMD5,MAPK14,ATP5PF,SNAPC4,MRPL19,ZNF696,BCAT2,MBD4,GOT2,EIF4A3,IMPAD1,JAZF1,PHTF1,AKR1B1,ZBTB22,TCEA1,SLC35C2,TECR,OGG1,ARID4A,CARM1,ELOF1,DEAF1,LARS,DPM1,RIOX2,RRM2,KMT2C,SOX4,PRPSAP1,MPC1,ASF1B,CHAF1A,ABHD5,RPL37,PAF1,GEMIN5,MAN2A2,UBTF,BRWD1,PQBP1,IARS2,CRCP,BAZ1B,ZNF268,CHEK2,GALNT10,CHPT1,MRPL13,RPS26,STARD3NL,RPS15,PIGN,GORASP1,ZNF768,NACA,MED13L,RPL15,MEF2A,THRAP3,TTF1,SRRT,CHKA,LYAR,DTL,NFATC3,ZNF449,MED10,PYURF,BUD31,ZNF335,YBX1,ACAD8,ZNF189,ALDH9A1,VOPP1,ATP5IF1,POLR2I,TSTA3,NUDT4,CIC,RPL6,GBA,EIF2A,SYVN1,SLTM,DAPK3,ISG15,NAP1L1,UAP1,NFIL3,NUP62,DNPH1,ZFP90,RBBP4,NANP,NIPSNAP2,HNRNPDL,PTDSS1,PDSS2,ZBTB24,ADNP2,TCF12,MBD1,PRKAB1,MMACHC,ASH1L,MPHOSPH8,GNPNAT1,MDH2,UCK2,SMARCA4,UCK1,PLAGL2,NSD3,CHKB,ORC1,IRF3,CHD1,EXT2,MEAF6,MXD1,PAIP1,SAP130,FARSA,RRN3,IARS,CD3EAP,AKAP8,RPN2,CYB5R1,CHTOP,UTP4,ZNF770,TMEM14C,RLIM,CSTF1,POU2AF1,ACSL5,CGAS,ZNF500,PCGF6,ATXN1,OGDH,MBD3,EIF3G,RPS9,PDHX,ZNF317,DAP3,STAT6,CHCHD1,ARNTL,CANT1,SCARB1,AKNA,MAPK1,BRD9,ABCA1,CBX4,PDF,NAT14,MIF,DNAJC2,GCLM,CDS2,MRPL42,ZNF316,EYA1,SCYL1,MRPS26,DBF4,KLF13,PAWR,MXD4,PIP4K2A,GFM2,HDDC2,MAN1A1,FGFR3,GART,KMT5A,PELO,RRBP1,NABP2,BRD7,ANP32A,MRPL11,STAT3,MYO5A,SLC25A1,AMPD2,TGFB1,SAMD4B,B3GALT6,GINS1,ELOVL5,ZDHHC18,CSNK1G2,GTF3C6,NASP,PSPC1,HELB,MIER1,NADK2,RCOR1,POLR3GL,MEN1,ATP5MF,ZNF407,SYMPK,TARS,MAPK3,TFEB,CNOT9,MTMR3,UPF1,ATAD2,KMT2B,ACAT1,SRSF3,ZMIZ1,PLOD3,TERF1 |
| 8.921e-26 | -57.68 | EED (embryonic ectoderm development) | protein interactions | 8726 | 477 | 170 | 17029 | 2761 |
RAB14,DDX47,NUP188,HNRNPAB,NOP2,CUL1,EBNA1BP2,SNRPD3,BRIX1,MAP1LC3B,MYEF2,RBM4,RPL23A,NUP210,NOL11,EIF4A3,INTS1,PDS5B,NOC2L,TRA2B,TCEA1,DNMT1,FTSJ3,PCBP2,SRSF10,SRPK2,CDC5L,RYBP,PLK1,SNRNP200,SEPT9,BAZ2A,EHMT1,HNRNPF,BRCA1,DIDO1,PBRM1,SLC25A5,RAB5B,DHX15,EIF3A,RPS27A,LUC7L3,RPS14,BAZ1B,RPS26,HDAC2,DDX42,SSRP1,FUBP1,PPIB,PHB2,DHX9,CTCF,EZH1,SRRT,NUP205,LMNA,RPN1,SMC3,DAD1,EFTUD2,ZNF326,NUP85,EEF1D,HP1BP3,SF3B6,RPS10,GTPBP4,RPS24,ARID1A,PLEC,ABCF1,SLTM,MATR3,XRCC5,SYNCRIP,RBM25,EPOP,RBMX,SMPD4,RUVBL2,TCOF1,YY1,SNRNP70,RBBP4,HNRNPDL,USP7,DNMT3A,DYNLL1,SUZ12,SF3B1,RAC1,HNRNPUL2,MYH9,SMARCA4,SAFB2,PCBP1,RPL11,PHC2,VAV1,HNRNPA2B1,MDM2,AHCTF1,STRBP,KDM2A,MTA1,NUP107,TARDBP,RPN2,RBM12B,RBM15,CFL1,PRPF19,RPL29,RAB7A,CRNKL1,PCGF6,TRIM28,SRSF1,SUPT16H,DDX17,DDOST,CLK3,HNRNPR,TBL3,SAFB,UHRF2,PDCD11,CBX4,NIFK,TRIP12,SRSF6,CDK2AP2,FLOT1,PAWR,ARGLU1,PNO1,ERH,PPP1R8,KMT5A,ANXA5,H2AFY,OSTC,FBL,HNRNPM,ADAM17,PSPC1,PRKDC,ILF3,RPL8,PPWD1,PCGF1,MEN1,RPL27A,DDX39A,API5,SNRPA,POLR2A,CBX3,CTSL,UTP20,MAGT1,HNRNPH3,KHSRP,HMGB2,DDX5,SRSF3,DDB1,DDX52 |
| 1.016e-25 | -57.55 | kidney-carcinoma | COSMIC cancer mutations | kidney-carcinoma | 3756 | 767 | 17385 | 2587 |
RAB14,FGFR1OP,KDM4A,PIGQ,XIAP,DHX8,LACTB2,PPP1R16B,FBXO22,EEF2K,CDKN2C,CDK5,NEK6,RABGAP1L,RAD23B,SRSF4,NUP153,RNF26,SENP1,PCBP2,MLST8,PLK3,BAK1,ERCC1,RHOBTB3,NRAS,GABPA,MCL1,TOPORS,SMC2,PPFIA3,MCM2,ICMT,RAB22A,ARF4,TRIM47,SMAD2,WDR11,RAD18,LIMK1,AXIN1,RNASEL,FBXL3,TFDP2,SMAD1,E2F2,PDCD4,PFKP,SSRP1,DDX42,CLSPN,RHOC,TRIO,RAB23,CERK,TOP2B,EZH1,EIF2AK4,PDCD7,ITGB5,APH1B,LMNA,DDX56,RNFT1,INPP5A,MCM5,FBXO7,PHF14,FOXN2,GEMIN4,NUP85,PHKG2,SRSF11,IFRD1,ETV3,DHX29,MYBL2,USP10,BCLAF1,SRSF5,MPG,ELK1,RHOB,PTPRF,DTWD1,OSBPL11,KPNA1,ETS2,DUSP3,MDH1,SNX14,RNF139,ALS2,EGLN1,RHOG,TRIM41,TRERF1,PTTG1,CHD1L,TPX2,MYH9,NUF2,PRKACA,KTN1,RAB21,PRKD3,FBXL6,DUT,UBA5,NUP107,ANAPC7,RNF19A,RBM15,ARL5A,SNX8,GOPC,IDH3A,MAP4K4,CIRBP,E2F3,MEF2D,DNAJA1,RAB1A,FKBP3,DDX17,KIF2A,TAF2,PPP2CA,CDC16,LSM6,CORO1C,HIPK2,RNF38,FUS,PDXK,PPP5C,GEN1,USP13,SRSF6,SESTD1,SIKE1,AKT1S1,UBE4A,IP6K2,IL21R,ETS1,IFT27,NEIL2,PPP1R3B,FBXO3,RPA2,ERH,PDCD10,CLIC4,ITGB8,SUV39H2,HUWE1,PPP1R8,ARF5,ARHGEF1,GTSE1,GEMIN6,UBE3B,FBXL19,IMPA2,LDHB,PDPK1,STAU1,PPP3CA,TK1,TNFAIP3,DDX24,POLK,TACC1,LDHA,MTMR12,RAB3IP,DDX39A,PICALM,RPA1,POLE,CCDC6,PITX1,MAPK6,FAM3C,PML,AEN,HMGB2,RGL1,CD81,YWHAH,IGBP1,FAF1,ANAPC4,COX15,DDX47,TRIM11,PPP1R15B,SNX15,CSNK2A1,GIT2,BIRC2,FANCL,ABL2,RAB8A,PCNA,NUP210,NT5DC1,IL6ST,PIK3R2,XRCC2,ETV6,MYBL1,ASB6,PTPRK,VPS13B,PLK1,SP3,PTPN18,SEPT9,RBX1,SNRPB,RAD51AP1,TLK1,GMFB,LNX2,CDC6,LRP5,UBE2V1,UTP3,BRCA1,PBRM1,RAB5B,USP21,RHEB,TRIM4,FBXO28,CHD3,E2F4,SOCS4,BCL7C,ADAM9,KPNA2,ACTB,DVL1,POT1,NUMB,FUBP1,DNAJB2,NKD2,LAMTOR3,RACGAP1,COX4I1,CDK13,ADCK5,RAB6A,DNAJB1,PPP3CB,RAPGEF6,VMP1,MBD2,XPA,AFF1,MAML1,CYTH1,ABHD2,TRAPPC9,ACSL3,LDB1,KRAS,MAP4K3,EIF2AK1,UBE4B,IRF5,RXRB,SDHB,MBIP,CDC27,PALB2,COX7A2L,ZDHHC7,RUVBL2,CCNB2,USP7,SART1,TRAF7,FOXM1,XAB2,SUMO2,PCBP1,LYN,DUSP22,RAD23A,RPL11,VAV1,CSDE1,MRPL50,PDK2,PSMA6,MDM2,PIN1,PDCD2,CORO1A,MINPP1,STRAP,SAP30L,SPSB3,DVL2,SNX25,KDM3B,ARHGAP17,BIRC3,BTG2,RAB7A,DNAJC9,FRAT2,NUP155,DCLRE1C,CHMP2B,MRPS14,ARL5B,EIF3H,USP36,SRSF1,DNAJC10,DHX16,PLEKHG4B,CLK3,RBL1,STK38,MAFK,FASTK,UHRF2,DNAJC17,AP1S1,XRCC3,NCOA1,USP53,SMAD4,RAD51D,INTS2,BCL2L12,MCM10,GOLIM4,CDT1,ARID5A,SMC6,HMGN3,ARF1,CSNK1A1,SCYL2,DNAJB9,TFRC,FZD6,PTPN2,HERC3,IRF4,SS18L1,DDX31,ORC3,CAMK2G,RNF5,CNTN5,RHOA,SNX2,TOP3A,ARHGEF12,PCGF1,DDX23,RAB18,TRIM26,KPNA4,PDCD6,FBXO41,ATP6V1D,BIRC5,TFE3,NEIL3,E2F1,USP20,IMPDH1,RBPJ,NR2F2,PGAM1,RPS6KC1,UBE2C,HIPK3,NUP188,MAX,PDCD6IP,ADAM10,USP39,CUL1,CCNB1,IKBIP,UBE2I,PARK7,RAB4A,SUCLG2,CDC25B,PLCL2,TFG,SMARCE1,DNMT1,CDC5L,ORAI2,KLF10,AKT2,PBK,GNG7,DDX20,AURKB,USP22,CCNF,RFC2,CBFB,RAB2B,EIF3A,MAP3K4,ANKRD10,HHEX,ITGB1,PTPN7,PTPDC1,TRAF5,ZMAT3,HDAC2,PTOV1,DDX58,RECQL,COX5B,DNAJC5,CHTF18,GSPT2,VAV2,PRKAA1,RRM1,KIF23,CYCS,NOTCH2,PSEN1,JMY,CFLAR,FKBP1A,RPN1,RNF121,MEX3C,SNX18,HDAC7,ATIC,PPP4R1,MSH2,DAPK1,FBXL7,CYC1,PIKFYVE,RNF135,GNAI2,ANKHD1,EEF1D,TERF2,SOCS5,PHF10,DDX28,PRIM2,PIGT,MFNG,PIP4K2C,ARID1A,RIT1,KDM3A,MAP2K2,AKAP1,FAS,PI4K2A,XRCC5,HMGN2,ADSS,CAT,DERL1,PFDN5,TMEM54,ACLY,PIAS2,USP32,PPP3R1,VCPIP1,GPI,YY1,MAP3K5,RNF14,CDK2,NRBP1,CDKN2A,DNMT3A,TP53RK,RAB11B,TRIP10,RAF1,SUZ12,RPS6KA1,SF3B1,RAC1,BCL2L1,SDHA,GNB2,EPM2A,PHC2,CRKL,TERF2IP,CCNA2,SHC1,KDM2A,RALB,SIAH1,UCHL5,LPIN2,SOCS6,TNPO2,CDKN1B,TP53BP2,CDK12,SAP30,CCT2,BRD4,MAPRE2,RFC3,HMGN4,ERF,NARF,CUL3,PKMYT1,CDC23,ASB13,POLG2,ERC1,TRIM28,DHX57,RAD51C,HSPA4,PPP2R5A,JAK1,ACYP1,SAFB,STAT1,SEL1L,H2AFX,TRIM32,PDCD11,XRCC4,ADAM23,PRPF4B,RHEBL1,POLQ,NCOR2,MECP2,TCF3,CBLL1,BLM,POFUT1,HMG20A,FOXO3,RAB11A,MAD2L2,JAKMIP1,WWP2,PIP5K1C,PTEN,AHSA1,AXIN2,PTPN11,COPS7B,UBE2M,NCOA2,MSH6,SMC4,JMJD4,LONRF3,NET1,NEK7,RABIF,ADSL,FBXO9,ANAPC2,KIF11,MARK2,FADD,CBX3,FBXO21,GNA12,PLD3,PFDN4,MFAP1,TFDP1,KHSRP,PPP1R11,DDX5,DUSP11,ESPL1,IPO4,GPR89B,DEF6,DDB1,RORB,POLA2,PIGM,IER2,UBE2E2,ST13,NF1,PTP4A3,UBE2Q1,AGFG1,SIRT2,KIF2C,FKBP2,USP48,BECN1,MAPK14,RNF103,MBD4,RAP1A,CDC42,EIF4A3,THADA,JAZF1,RAB35,PPP1R12C,TCEA1,OGG1,ARID4A,TRIM14,SRPK2,COPS8,TRIM8,NCK1,VHL,RRM2,WDR82,PITPNB,KMT2C,SOX4,STK17B,GEMIN5,CXXC4,UEVLD,PPM1G,CAB39,STK11,CHEK2,COPS6,MRPL13,UBE2D3,PIGN,PPP1R2,PPP1R12A,NACA,PCSK7,MED13L,THRAP3,RGS2,XPO7,NUP205,BCL2,KNTC1,UBE3C,ZRANB1,MCPH1,N4BP2,CSNK1G3,ALDH9A1,ZNF189,CREG1,DAPK3,ARHGAP15,MASTL,UAP1,SIAH2,PITPNA,YWHAZ,NUP62,RBBP4,TOB1,SMARCD1,WASF2,MBD1,TCF12,PRKAB1,SNX27,ASH1L,MDH2,PMS2,SMARCA4,PLAGL2,ORC1,TWF2,CHD1,MXD1,USP5,SAR1A,AKAP8,PPP6C,CS,SCYL3,ABI1,DNAL4,EBAG9,RLIM,POU2AF1,RNF25,PCGF6,METTL2A,GLO1,OGDH,BICD2,FANCE,PDHX,RAD54B,DAP3,TAB2,TULP3,STAT6,FKBP5,SCARB1,GAS2,USP11,SMURF1,MAPK1,PPP2R2D,CBX4,DNAJC2,CDS2,SH2D3A,CASP6,RAE1,SHPRH,EYA1,SCYL1,DBF4,NUP54,CHIC2,MXD4,PIP4K2A,RGS1,FBXO5,FGFR3,CTNNBL1,KLHL20,TANK,ARHGEF2,STAT3,FRMD8,AMPD2,CSNK1G2,ADAM17,HMGN1,ASPM,TFEB,MAPK3,MTMR3,COX8A,SRSF3,ZMIZ1,IDH3B,HRAS,TERF1,RAB3IL1 |
| 1.080e-25 | -57.49 | RNA splicing, via transesterification reactions with bulged adenosine as nucleophile | biological process | GO:0000377 | 282 | 115 | 17256 | 2622 |
SART1,CHERP,XAB2,SF3B1,RBM8A,DHX8,USP39,SNRPD3,PCBP1,PAPOLA,SF3B2,HNRNPA2B1,SNUPN,EIF4A3,METTL14,SRSF4,GPATCH1,KHDC4,TRA2B,AQR,RBM15,STRAP,CCAR1,PCBP2,CSTF1,SRPK2,PRPF19,SRSF10,CDC5L,SNRNP200,POLR2L,POLR2G,SNRPB,PPIE,SMU1,CRNKL1,HNRNPF,POLR2D,RNPS1,LSM8,DDX20,PRPF3,BUD13,TXNL4A,LUC7L,CLNS1A,DHX15,SRSF1,DDX17,SUGP1,GEMIN5,DHX16,HNRNPR,LSM6,LUC7L3,U2SURP,PQBP1,PRPF4,FUS,SNRPG,SMNDC1,GEMIN7,DDX42,CWC25,PRPF4B,CDC40,LIME1,ZCCHC8,POLR2K,SRSF6,DHX9,CDK13,PRPF39,PDCD7,METTL3,SRRT,PRPF18,GTF2F1,RAVER2,RBM17,SNRNP25,DNAJC8,CTNNBL1,CWC27,EFTUD2,BUD31,GEMIN6,YBX1,GEMIN4,CPSF4,PABPC1,LUC7L2,HNRNPM,RBM15B,SRSF11,YTHDC1,POLR2I,PSPC1,SF3B6,PPWD1,SRSF5,DDX39A,SYMPK,SF3A2,SNRPA,POLR2A,DDX23,SYNCRIP,POLR2J,RBMX,HNRNPH3,PRMT7,DDX5,SRSF3,SNRNP70 |
| 1.080e-25 | -57.49 | mRNA splicing, via spliceosome | biological process | GO:0000398 | 282 | 115 | 17256 | 2622 |
SART1,CHERP,XAB2,SF3B1,RBM8A,DHX8,USP39,SNRPD3,PCBP1,PAPOLA,SF3B2,HNRNPA2B1,SNUPN,EIF4A3,METTL14,SRSF4,GPATCH1,KHDC4,TRA2B,AQR,RBM15,STRAP,CCAR1,PCBP2,CSTF1,SRPK2,PRPF19,SRSF10,CDC5L,SNRNP200,POLR2L,POLR2G,SNRPB,PPIE,SMU1,CRNKL1,HNRNPF,POLR2D,RNPS1,LSM8,DDX20,PRPF3,BUD13,TXNL4A,LUC7L,CLNS1A,DHX15,SRSF1,DDX17,SUGP1,GEMIN5,DHX16,HNRNPR,LSM6,LUC7L3,U2SURP,PQBP1,PRPF4,FUS,SNRPG,SMNDC1,GEMIN7,DDX42,CWC25,PRPF4B,CDC40,LIME1,ZCCHC8,POLR2K,SRSF6,DHX9,CDK13,PRPF39,PDCD7,METTL3,SRRT,PRPF18,GTF2F1,RAVER2,RBM17,SNRNP25,DNAJC8,CTNNBL1,CWC27,EFTUD2,BUD31,GEMIN6,YBX1,GEMIN4,CPSF4,PABPC1,LUC7L2,HNRNPM,RBM15B,SRSF11,YTHDC1,POLR2I,PSPC1,SF3B6,PPWD1,SRSF5,DDX39A,SYMPK,SF3A2,SNRPA,POLR2A,DDX23,SYNCRIP,POLR2J,RBMX,HNRNPH3,PRMT7,DDX5,SRSF3,SNRNP70 |
| 1.645e-25 | -57.07 | TARTE_PLASMA_CELL_VS_PLASMABLAST_DN | MSigDB lists | TARTE_PLASMA_CELL_VS_PLASMABLAST_DN | 296 | 118 | 17377 | 2626 |
CYTIP,TXN,ADD1,FOXM1,SUMO2,TMEM97,UCK2,SMARCA4,EBNA1BP2,KIF2C,ORC1,SNRPD3,CCNB1,OAT,GIT2,MRPL19,SSR1,PAPOLA,KIFC1,PCNA,CCNA2,DUT,KIF14,ATP13A3,TRA2B,KIF22,CDC25B,CORO1A,EIF5,BAK1,PPIF,CCT2,CLCN3,RFC3,CDC123,CPOX,MKI67,MRPL12,RRM2,ARHGDIB,CDC6,CCNF,VDAC1,EIF3A,CHAF1A,PRIM1,KIF2A,HSPA4,SCAP,TIMM17A,ITGB1,UQCRH,KPNA2,SNRPG,MAPK1,PFKP,UBE2D3,RECQL,GCLM,NDUFV2,EWSR1,NDUFS1,ANXA6,PPP1R2,CASP6,PDAP1,RRM1,TKT,KIF23,NKRF,CYCS,TOP2B,TFRC,EBP,RB1,GART,HUWE1,ATIC,ANP32A,YBX1,AFF1,AHCY,OSTF1,MVP,MYO5A,LDHB,FDFT1,GINS1,NASP,MAPKAPK3,PRKDC,PSMA1,DDX39A,KIF11,TARS,FAS,RPA1,CBX3,SDHB,SLC19A1,MTHFD2,CDC27,PDLIM1,ELMO1,PRPS2,MAPK6,DBI,NFIL3,SLC16A1,ASNA1,HMGB2,SRSF3,GPI,UBE2C,YWHAH,MRPL3,ESPL1,BYSL |
| 1.829e-25 | -56.96 | MORF_SOD1 | MSigDB lists | MORF_SOD1 | 262 | 109 | 17377 | 2626 |
TMEM106C,KARS,H2AFZ,HNRNPAB,CHERP,DYNLL1,RAC1,ENSA,STARD7,CCNB1,SDHA,PARK7,BCAP31,RAD23A,SF3B2,CALM2,HNRNPA2B1,PCNA,UTP18,MTA1,RAD23B,CS,HADHB,TARDBP,TECR,EBAG9,CCT2,SNRNP200,CDC123,PSMB7,VDAC2,GLO1,TMEM147,CDC23,VDAC1,TRIM28,RHEB,CLNS1A,SRSF1,STOML2,KIF2A,HSPA4,DHX16,TBL3,PSMD8,PPM1G,MPV17,COX5A,UQCRH,KPNA2,SNRPG,PSMC1,AP2S1,MYL12B,HDAC2,NDUFV2,NDUFS1,MRPL9,SCAMP3,SEC61G,PHB2,DAP,DCTN2,COX4I1,CYCS,SLC4A2,XPO7,PSMD9,ERH,NDUFV1,HUWE1,AHSA1,ATIC,BANF1,MSH2,PTPN11,EI24,NDUFS8,PTGES3,CYC1,MAML1,FBL,TMED2,NUDC,IFRD1,HMGN1,POLR2I,NSDHL,ILF3,TUFM,EIF4H,MAP2K2,SNRPA,TARS,RPA1,CBX3,PDCD6,PRDX3,MFAP1,RBMX,PRPS2,ACLY,PGRMC1,LRPPRC,MDH1,RUVBL2,NDUFS5,MRPL3,SSSCA1 |
| 2.105e-25 | -56.82 | CDC5L (cell division cycle 5 like) | protein interactions | 988 | 588 | 196 | 17029 | 2761 |
DDX47,COPA,NOP2,UBN1,NF1,DHX8,CUL1,USP39,KIF2C,SNRPD3,CCNB1,RBM4,FANCI,SF3B2,DST,PSMD1,EIF4A3,INTS1,SRSF4,DNM2,KHDC4,CDC25B,FTSJ3,PCBP2,SEH1L,CDC5L,SRP72,PLK1,ERCC1,USO1,SNRNP200,SEPT9,HNRNPF,SREK1,AURKB,BRCA1,SMC2,ANLN,RFC2,LUC7L,DHX15,ARF4,AHNAK,BRD2,RAD18,EIF2D,U2SURP,KPNA2,ACTB,PSMC1,PFKP,ANXA11,DDX42,CCZ1,TRIO,DHX9,RACGAP1,COPG2,CDC73,COPB2,LMNA,RPN1,SUB1,SMC3,EIF2S2,MCM5,ZNF746,EFTUD2,RTCB,CAPZA1,MSH2,GEMIN4,MRPL40,MVP,SF3B6,USP10,ARID1A,PLEC,SRSF5,SEPT7,SF3A2,CCT8,PSMC4,CAND1,RXRB,GNAS,CDC27,GOLGA2,NSF,RBMX,EXOC4,YJU2,YWHAZ,RUVBL2,EHD4,SNRNP70,RBBP4,CDK2,CDKN2A,SMARCD1,SART1,CYLD,CHERP,SF3B1,CHD1L,TPX2,MYH9,SMARCA4,NUF2,ORC1,AP1B1,PCBP1,HNRNPA2B1,SHC1,UCHL5,AKAP8,UBA5,NUP107,TARDBP,ANAPC7,PRPF19,CCT2,CDKN2AIP,BRD4,RFC3,PPIE,CUL3,NUP155,PRPF3,DNAJA1,CDC23,SRSF1,DDX17,CDC16,HNRNPR,PSMD3,FUS,DYNC1LI2,TUBB,ZC3HC1,PRPF4B,MCM10,CDT1,DCTN2,TRAK1,ARGLU1,TUBGCP2,SCYL2,WRNIP1,RBM17,KIF5B,RPA2,PSMD2,CTNNBL1,HUWE1,PPP1R8,SEC24C,ARF5,PELO,ARHGEF1,GEMIN6,ARHGEF2,BRD7,ORC3,UBE2M,MSH6,HNRNPM,SMC4,NUDC,SPTAN1,STAU1,SNX2,BTAF1,PRKDC,WDR18,PARP4,ILF3,ANAPC2,RANGAP1,LRRC1,DDX39A,MACF1,KIF11,API5,SYMPK,PICALM,MARK2,SNRPA,RPA1,SH3BP5,UPF1,CCZ1B,DDX5,ISY1-RAB43,FAF1,DDB1 |
| 2.682e-25 | -56.58 | GO_ENZYME_BINDING | MSigDB lists | GO_ENZYME_BINDING | 1684 | 408 | 17377 | 2626 |
FGFR1OP,TSC2,KDM4A,PRKCSH,ADAM10,CUL1,CCNL2,CCNB1,UBE2I,PARK7,CDK5,CALM2,CDKN2C,PA2G4,USF1,NEK6,RABGAP1L,RAB4A,FIZ1,DNM2,NUP153,CRY2,CDC25B,MAST2,ECD,DNMT1,PCBP2,CDC5L,RHOBTB3,AKT2,DDX20,TOPORS,DCUN1D5,USP22,NUTF2,MCM2,SLC25A5,RFC2,STOML2,BRMS1,WAS,SMAD2,RAD18,AXIN1,ITGB1,ATP6V0C,SMAD1,TRAF5,ARRB2,LONP2,HDAC2,SVIP,PPIB,PRKAA1,CUTA,TRIO,STRN4,B4GALT1,SLC4A2,TOP2B,PARN,CDC73,LMNA,NPLOC4,NDUFS7,CFLAR,DDRGK1,RTKN,TFAP4,HDAC7,FBXO7,ZNF326,MSH2,ATP6V0A2,PIK3IP1,MVP,SYTL3,PPP6R1,PHKG2,LUC7L2,SOCS5,CYFIP1,ETV3,RB1CC1,MTA2,UHRF1BP1,ADRB2,CYB5A,PHF6,FAS,AKAP1,XRCC5,CAT,DERL1,EPRS,SCARB2,FNTA,GOLGA2,NSF,DUSP3,CSK,FAM83D,PIAS2,CABIN1,GPI,PPP6R3,MAP3K5,RNF14,PDLIM5,RNF139,CDKN2A,ALS2,EGLN1,PPP1R37,ANKRD27,ATXN3,CAST,RAF1,RAC1,WDTC1,TPX2,TBC1D13,BCL2L1,AP1B1,PRKACA,GLRX3,RCOR3,GNB2,APP,ANKIB1,CPNE3,MOAP1,CCNA2,SHC1,ATP2A2,SP100,RALB,TBC1D22A,TBC1D14,NSFL1C,TNPO2,CDKN1B,ANAPC7,MAVS,RNF19A,ATF2,RPRD1B,ATP6V1G1,ANKLE2,CCT2,SHOC2,EID1,CUL3,ATP6V0A1,ELP4,DNAJA1,MEF2D,ERC1,TRIM28,CHCHD3,PEX5,CHMP4A,PPP2R5A,JAK1,HINT1,SAFB,CORO1C,H2AFX,STAT1,TICAM1,ATF6,TUBB,USP13,NCOR2,RPS2,SCAMP3,MECP2,TCF3,FLOT1,SDF2L1,ETS1,FOXO3,MAD2L2,JAKMIP1,MAT2B,CCNK,RPA2,PPP1R3B,ADD3,PDCD10,PTEN,CENPJ,PRDM4,PRC1,AXIN2,PTPN11,ANXA5,CREB1,CITED2,UBE2M,NCOA2,LDHB,PDPK1,MOB4,PPP3CA,STAU1,TNFAIP3,KAT2A,NET1,PARP4,JTB,RFXANK,LDHA,ANAPC2,KCNQ1,ZP3,PDE3B,KIF11,POLR2A,FADD,CBX3,INF2,TMEM127,PRDX3,MAPK6,LRPPRC,PML,DDX5,IGBP1,YWHAH,THAP5,FAF1,ANAPC4,IPO4,PHRF1,YTHDC2,ENSA,UBE2Z,SIRT2,SNRPD3,BECN1,MAPK14,MAP1LC3B,FANCI,FANCL,RAB8A,RAP1A,PCNA,CDC42,GOT2,ATG3,DPYSL2,ZNHIT6,PIK3R2,SRI,PPP1R12C,PTPRK,CDC37,PLK1,RBX1,NCK1,VHL,EZR,CDC6,UBE2V1,ARHGDIB,BRCA1,PRKRA,PRPSAP1,RHEB,OPTN,PAF1,ADAM9,CAB39,ACTB,KPNA2,ROCK1,DVL1,CHEK2,CLU,POT1,SLC12A7,TBC1D12,PPP1R12A,DNAJB2,UBXN1,CIB1,NKD2,MEF2A,RACGAP1,PPP3CB,DNAJB1,NCKAP1,XPO7,DOCK11,RAPGEF6,RB1,KIF13B,ZNF746,CTR9,BCL2,YBX1,MAML1,HDHD2,LDB1,ACSL3,UBE4B,SYVN1,APPL1,DAPK3,MASTL,GOLGA4,CDC27,ODF2,EXOC4,SIAH2,YWHAZ,RUVBL2,RBBP4,TOB1,N4BP2L2,RNF114,USP7,PRKAB1,CYLD,FOXM1,SUMO2,TOR1AIP1,SLC2A1,SMARCA4,TWF2,LYN,RAD23A,RRN3,MDM2,CCDC50,IARS,WDR44,PIN1,PPME1,KIF14,AKAP8,PDCD2,DVL2,TIMP2,PPP1R18,NXT1,RAB7A,TOR1AIP2,BICD2,VDAC1,TOLLIP,DNAJC10,ATP1A1,TULP3,STK38,STAT6,NCOA1,MAPK1,TSPAN5,ABCA1,CBX4,ZC3HC1,PARD3,KIF3B,GCLM,MCM10,SHPRH,SMC6,ARFIP2,PAWR,MYO9B,GGA2,DCUN1D4,FZD6,FBXO5,PTPN2,CTNNBL1,TANK,H2AFY,ARHGEF2,ABCD1,ATG13,FBL,STAT3,MYO5A,MICAL3,TGFB1,TELO2,PPP1R9B,MLEC,PRKDC,PPP1R21,PRKAR1B,RFFL,RANGAP1,BORA,HSPA1B,MAPK3,MFN2,CACNB1,BIRC5,E2F1,ACAT1,PKD2,SRSF3,UBE2C,PGAM1 |
| 2.686e-25 | -56.58 | CUL1 (cullin 1) | protein interactions | 8454 | 679 | 217 | 17029 | 2761 |
TXN,HNRNPAB,NOP2,KDM4A,KMT2E,CUL1,EBNA1BP2,SNRPD3,BRIX1,RBM4,MRPL19,PABPC4,FBXO22,RPL23A,CALM2,PCNA,EIF4A3,SRSF4,FBXW2,TRA2B,CRY2,CDC25B,TFG,FTSJ3,PCBP2,CARM1,TIMM50,CDC5L,COPS8,RBX1,SNRPB,NSUN2,MRPL12,HNRNPF,SREK1,PSMG1,MCL1,DCUN1D5,CCNF,SLC25A5,DHX15,TRIM47,TIMM13,LUC7L3,RPS14,U2SURP,KPNA2,ACTB,CHEK2,CLU,COPS6,FBXL3,MYL12B,SSRP1,RPS15,EWSR1,PPP1R12A,UBXN1,DHX9,TIA1,RPL15,RACGAP1,CDC73,MYL6B,GNS,TFAP4,LYAR,DDX56,SNX18,FBXO7,RTCB,CTPS1,YBX1,RBM3,AHCY,FBXL7,MRM3,PABPC1,EEF1D,HP1BP3,EIF3L,RPS10,RPL6,PSMA1,RPS24,ARID1A,SRSF5,PKM,CCT8,MATR3,PSMB3,RPL36,CAND1,SDHB,EPRS,NAP1L1,KPNA1,SYNCRIP,QARS,YWHAZ,ATP5F1A,RUVBL2,SNRNP70,CDK2,HNRNPDL,KARS,CORO7,RPLP2,UGP2,DYNLL1,SF3B1,PTTG1,MYH9,IRF3,POMP,SDHA,COMMD8,RPL11,CSDE1,HNRNPA2B1,SAP130,OIP5,FARSA,MDM2,PSMA6,CCNA2,STRBP,GRSF1,MRPS27,NSFL1C,CDKN1B,PDIA6,PRPF19,CCT2,RPL35,EID1,BTG2,RNPS1,CUL3,CIRBP,RPL38,DNAJC9,SLBP,DNAJA1,TRIM28,RPS9,RPSA,SRSF1,DDX17,PPP2CA,DNAJC10,HSPA4,HNRNPR,HIPK2,RPLP1,FUS,PDXK,SCARB1,SNRPG,FAU,USP11,TUBB,ZC3HC1,RPS2,RAE1,SRSF6,CDT1,AGO2,CDCA3,MRPS26,BRAP,NKRF,DCUN1D4,WDR5,SLC25A43,TUT4,WWP2,FBXO3,RPA2,NABP2,RPL19,COPS7B,NAP1L4,MRPL11,UBE2M,HNRNPM,SPTAN1,PPAN,STAU1,RPL8,ILF3,FBXO9,RPL27A,BORA,SNRPA,TARS,PRDX1,HSPA1B,RPA1,CBX3,FBXO21,PDCD6,RPL32,CCDC6,PRDX3,HNRNPH3,PML,E2F1,ACAT1,KHSRP,DDX5,RBPJ,SRSF3,PURA,FAF1,DDB1,GPATCH4 |
| 3.051e-25 | -56.45 | mRNA processing | biological process | GO:0006397 | 459 | 158 | 17256 | 2622 |
DDX47,THOC1,PHRF1,RBM8A,ALKBH5,DHX8,USP39,SNRPD3,RBM4,PAPOLA,SF3B2,SNUPN,NSRP1,EIF4A3,METTL14,SRSF4,GPATCH1,KHDC4,TRA2B,ECD,CCAR1,PCBP2,SRPK2,SRSF10,CDC5L,SNRNP200,SNRPB,HNRNPF,DDX20,SREK1,LUC7L,CLNS1A,DHX15,IWS1,PAF1,GEMIN5,LUC7L3,U2SURP,PQBP1,PRPF4,RNASEL,SMNDC1,GEMIN7,DDX42,PRPF38B,LIME1,ZCCHC8,POLR2K,DHX9,CDK13,THRAP3,PRPF39,PDCD7,METTL3,CDC73,SRRT,PRPF18,RAVER2,SNRNP25,CMTR2,EFTUD2,BUD31,ZNF326,YBX1,GEMIN4,CPSF4,PABPC1,LUC7L2,SRSF11,POLR2I,AGGF1,SF3B6,SUGP2,SRSF5,SF3A2,RBM38,SYNCRIP,RBM25,POLR2J,RBMX,PRMT7,ZNF830,SNRNP70,TSEN15,SART1,SARNP,CHERP,SF3B1,XAB2,PRKACA,PCBP1,APP,HNRNPA2B1,RBM23,ZNF473,GRSF1,TARDBP,AQR,AHCYL1,CHTOP,RBM15,STRAP,CDK12,ZC3H3,PRPF19,CSTF1,POLR2G,POLR2L,PPIE,RNPS1,POLR2D,CRNKL1,SMU1,LSM8,SLBP,PRPF3,BUD13,TXNL4A,SRSF1,DDX17,SUGP1,LSM6,HNRNPR,DHX16,SNRPG,FUS,PDCD11,PRPF4B,CWC25,CDC40,SRSF6,HABP4,JMJD6,GTF2F1,RBM17,DNAJC8,CTNNBL1,CWC27,PPP1R8,GEMIN6,CNOT6L,GTF2H2,HNRNPM,RBM15B,YTHDC1,PSPC1,TBRG4,PPWD1,DDX39A,SYMPK,SNRPA,POLR2A,DDX23,HNRNPH3,KHSRP,ZRANB2,DDX5,SRSF3 |
| 4.184e-25 | -56.13 | ROSTY_CERVICAL_CANCER_PROLIFERATION_CLUSTER | MSigDB lists | ROSTY_CERVICAL_CANCER_PROLIFERATION_CLUSTER | 132 | 71 | 17377 | 2626 |
POLA2,H2AFZ,FOXM1,MRPS15,PTTG1,TPX2,KIF2C,CCNB1,COMMD8,FANCI,KIFC1,OIP5,PCNA,CCNA2,KIF14,TACC3,PLK1,RAD51AP1,PBK,KIF15,MKI67,RRM2,NUSAP1,CDC6,AURKB,BRCA1,SMC2,MCM2,CCNF,SHCBP1,GINS4,ASF1B,HSPB11,KIF18B,CEP55,H2AFX,KPNA2,ANP32E,LRP8,POLQ,MCM10,HJURP,CENPF,DBF4,CDCA8,CDCA3,KIF23,RACGAP1,NCAPG,SPAG5,SAC3D1,FBXO5,EBP,DTL,PRC1,GTSE1,CENPM,SMC4,GINS1,TK1,ASPM,MYBL2,KIF11,ATAD2,BIRC5,E2F1,HMGB2,UBE2C,CCNB2,ESPL1,CDKN2A |
| 6.434e-25 | -55.70 | chromosome organization | biological process | GO:0051276 | 1101 | 295 | 17256 | 2622 |
PDCD6IP,H2AFZ,KDM4A,CXXC1,CCNB1,MIS12,KIFC1,RAD23B,PDS5B,TAF5L,SMARCE1,DNMT1,SEH1L,ERCC1,EHMT1,WDHD1,MIER2,SMC2,USP22,AURKB,MCM2,RFC2,GINS4,PRIM1,DOT1L,BRMS1,HHEX,BRD2,KIF18B,RPS27A,OGT,RRS1,HDAC2,SSRP1,RECQL,MAPRE1,PHF23,MUM1,PRKAA1,DHX9,KIF23,TOP2B,EZH1,PMF1,SUPT7L,CDC73,SPAG5,SMC3,HDAC7,MSH2,TNRC18,NUP85,TERF2,PRIM2,TSPYL4,ZMYND11,MTA2,ARID1A,KDM3A,XRCC5,EPOP,SETD3,TEX30,CABIN1,NDE1,YY1,ZNF830,CDK2,SGF29,CDKN2A,ZNF207,NDC1,DNMT3A,SUZ12,UBR2,CHD1L,PTTG1,NUF2,INO80E,TERF2IP,CCNA2,AHCTF1,SP100,KDM2A,MTA1,NUP107,ATF2,SAP30,PSRC1,BRD4,RFC3,KAT7,TAOK1,CUL3,ELP4,NUSAP1,CDC23,H2AFV,GAR1,TRIM28,CENPU,SUPT16H,KIF2A,RAD51C,CHMP4A,DSN1,SAFB,NSMCE2,H2AFX,BEND3,PPP5C,EYA2,DYNC1LI2,TWNK,MECP2,BABAM1,JMJD6,WDR5,BLM,SPDL1,RAB11A,HMG20A,RPA2,SUV39H2,HUWE1,PRDM4,PRC1,AXIN2,NAA50,KANSL2,COPS7B,NAP1L4,GTF2H2,MSH6,SMC4,NUDC,ZFP64,KAT2A,CBX3,RPA1,KIF18A,POLE,HMGB2,TAF6,ESPL1,PURA,DDB1,IPO4,POLA2,UBN1,KMT2E,SIRT2,TAF6L,KIF2C,BECN1,TET3,PCNA,NOC2L,KIF22,MCMBP,ARID4A,CARM1,ELOF1,RYBP,PLK1,COPS8,RBX1,BAZ2A,TLK1,RIOX2,WDR82,UTP3,PBRM1,KMT2C,USP21,ASF1B,CHAF1A,UBTF,PAF1,BRWD1,CHD3,BAZ1B,ACTB,VPS4A,COPS6,POT1,NAA60,HJURP,PHB2,CENPF,CTCF,RACGAP1,RLF,ARID1B,RB1,MBD2,XPA,ZNF335,CTR9,KNTC1,HP1BP3,LDB1,RTF1,DAPK3,MBIP,NAP1L1,CDCA5,PRMT7,NUP62,RUVBL2,RBBP4,SMARCD1,MBD1,USP7,CHMP2A,ASH1L,ARID2,DYNLL1,SMARCA4,NSD3,CHD1,MEAF6,HNRNPA2B1,OIP5,ANKLE1,BABAM2,KMT5C,BRPF3,KIF14,AKAP8,TOP1MT,SAP30L,KDM3B,FAM172A,PCGF6,NUP155,DCLRE1C,CHMP2B,KDM1B,MBD3,USP36,RAD54B,RBL1,CEP55,CHMP4B,XRCC3,ANP32E,NCOA1,H3F3A,BRD9,CBX4,RAD51D,DNAJC2,MTERF1,RAE1,EYA1,SHPRH,CDT1,CDCA8,SMC6,HMGN3,NCAPG,IRF4,KMT5A,PELO,ANP32A,H2AFY,SS18L1,PTGES3,CENPM,FBL,GINS1,TELO2,HMGN1,HMGN5,NASP,HELB,PRKDC,MIER1,TOP3A,RCOR1,RANGAP1,PRMT2,MEN1,PCGF1,LEMD2,UPF1,ATAD2,BIRC5,L3MBTL3,KMT2B,CENPT,TAF12,CHMP7,TERF1 |
| 7.535e-25 | -55.55 | GO_RNA_SPLICING | MSigDB lists | GO_RNA_SPLICING | 344 | 129 | 17377 | 2626 |
DDX47,THOC1,RBM8A,DHX8,USP39,SNRPD3,RBM4,PAPOLA,SF3B2,SNUPN,EIF4A3,NSRP1,METTL14,SRSF4,GPATCH1,TRA2B,CCAR1,PCBP2,SRSF10,SRPK2,CDC5L,SNRNP200,SNRPB,HNRNPF,SREK1,DDX20,LUC7L,DHX15,CLNS1A,IWS1,GEMIN5,LUC7L3,PQBP1,PRPF4,SMNDC1,GEMIN7,PRPF38B,ZCCHC8,POLR2K,DHX9,CDK13,THRAP3,PRPF39,PDCD7,METTL3,SRRT,PRPF18,RAVER2,SNRNP25,EFTUD2,BUD31,ZNF326,YBX1,GEMIN4,CPSF4,PABPC1,LUC7L2,SRSF11,POLR2I,SUGP2,SRSF5,SF3A2,RBM38,SYNCRIP,POLR2J,RBM25,RBMX,PRMT7,SNRNP70,TSEN15,SART1,IVNS1ABP,SF3B1,XAB2,RRAGC,C2orf49,PCBP1,HNRNPA2B1,TARDBP,AQR,RBM15,CDK12,STRAP,PRPF19,CSTF1,POLR2L,POLR2G,PPIE,POLR2D,RNPS1,CRNKL1,PRPF3,BUD13,TXNL4A,SRSF1,PPP2CA,SUGP1,DHX16,LSM6,HNRNPR,SNRPG,PRPF4B,CDC40,SRSF6,JMJD6,GTF2F1,RBM17,DNAJC8,CTNNBL1,CWC27,PPIG,PPP1R8,GEMIN6,HNRNPM,RBM15B,YTHDC1,PPP1R9B,HELB,PSPC1,PPWD1,DDX39A,POLR2A,SNRPA,DDX23,HNRNPH3,KHSRP,ZRANB2,DDX5,SRSF3 |
| 9.034e-25 | -55.36 | establishment of protein localization | biological process | GO:0045184 | 1418 | 357 | 17256 | 2622 |
CCDC93,TMED7,RAB14,NUP188,PDCD6IP,TSC2,TAP1,AP3M2,SYNRG,RIC1,PARK7,RPL23A,CDK5,NAPG,SNUPN,RABGAP1L,RAB4A,SRSF4,AP1M1,DNM2,AP2B1,NUP153,SEH1L,SRP72,PGAP2,USO1,TMEM115,ATG9A,AKT2,MCL1,NUTF2,ICMT,MCFD2,RAB22A,RAB2B,ARF4,PLEKHF2,HHEX,SMAD2,TMED10,RPS27A,RPS14,EIF2D,VIPAS39,ATP6V0C,BTF3,RRS1,ARRB2,NMD3,ZMAT3,LONP2,AAAS,NXT2,GGA1,SEC61G,RAB23,ACAP1,TMED3,PSEN1,VPS25,COPG2,NPLOC4,COPB2,ATG4A,SNX18,FBXO7,TNPO3,ATP6V0A2,MVP,CPSF4,SYTL3,NUP85,TMED2,SRSF11,NAGPA,EIF5A,TIMM8B,GCC2,RPS10,RPS24,SSR2,SRSF5,MTX1,TOMM40,PTTG1IP,GOSR1,RHOB,DERL1,SEC31A,SCARB2,KPNA1,NSF,PPP3R1,SGF29,SNX14,NUP58,EXOC3,ANKRD27,NDC1,SARNP,SYS1,RAB11B,RAF1,GPR89A,ANK3,VTI1A,C5orf30,MYH9,TBC1D13,AP1B1,STAM,MOAP1,RAB21,AHCTF1,TBC1D22A,TBC1D14,NUP107,TNPO2,TAP2,ZC3H3,ATP6V1G1,SNX8,SEC61B,GOPC,WBP2,RNPS1,POLR2D,RPL38,SLBP,ATP6V0A1,RAB1A,AP4E1,ERC1,SERP1,PEX5,CHMP4A,HSPA4,SEC61A1,VPS26B,RAB24,CORO1C,RPLP1,SEL1L,PITRM1,RPS2,SCAMP3,SRSF6,TRAK1,BTN3A1,IFT27,RAB11A,WRB,JAKMIP1,RPL17,ARF5,RPL19,UPF2,MTX2,PPP3CA,TNFAIP3,GUK1,DENND1B,DENND4C,RPL8,RABIF,RAB3IP,DDX39A,MACF1,RPL27A,YIF1A,KIF18A,HGS,RPL32,STX18,PML,YWHAH,GPR89B,IPO4,VPS29,SNAPIN,POLA2,MTX3,COPA,THOC1,RBM8A,SNX15,ALKBH5,UBE2Q1,AGFG1,RUFY1,SEC16A,SSR1,RAB8A,NUP210,RAP1A,TIMM23,EIF4A3,AP3S2,RAB35,ATG3,PIK3R2,RP2,TIMM50,CDC37,VPS13B,PLK1,FYTTD1,LARS,TLK1,RAB5B,STX16,LSG1,OPTN,NECAP2,RPL37,TRAM2,TBC1D17,TIMM13,EIF4ENIF1,HSPB11,GRIPAP1,UEVLD,TIMM29,MIA2,ARRDC1,KPNA2,VPS4A,CLU,RPS26,POT1,ATP6V0E1,C2CD5,RPS15,TBC1D12,GORASP1,PHB2,CENPF,RPL15,RAB6A,XPO7,RHBDD1,NUP205,RINL,KIF13B,ARL6IP1,GLE1,LRSAM1,ATP6V0D1,PREB,KDELR1,RPL6,SYVN1,ZDHHC3,NPIPA1,RPL36,TSC1,GOLGA4,SNAP23,EXOC4,ZDHHC7,SIL1,NUP62,CTSA,RUVBL2,CHMP2A,SNX27,CORO7,TOMM20,RPLP2,COPE,ATP6V1B2,LYN,RPAIN,BCAP31,RPL11,HNRNPA2B1,ATP6V0B,ANKLE1,MDM2,SAR1A,KIF14,AKAP8,BCAP29,SCAMP4,AHCYL1,CLTB,CHTOP,LMAN1,CHP1,SNX25,RPL29,NXT1,RPL35,PPT1,RAB7A,NUP155,BICD2,ERBIN,CHMP2B,RPS9,RHBDF2,RPSA,SRSF1,SURF4,VPS26C,TOMM6,TIMM17A,CEP55,ARNTL,AP1S1,CHMP4B,SMURF1,AP2S1,ABCA1,PARD3,CDC40,GOLPH3L,RAE1,NUP54,VPS45,ARFIP2,TIMM21,ARF1,GGA2,AP3S1,TFRC,KLHL20,SEC24C,RRBP1,NABP2,ARHGEF2,H2AFY,STAT3,CAMK2G,MYO5A,TGFB1,ZDHHC18,NASP,SNX2,SCFD2,COG1,SYMPK,MFN2,RAB18,SEC23IP,UPF1,ATP6V1D,PDCD6,KPNA4,GOLGA7,SNAP29,RBPJ,SPCS3,SRSF3,ATP6V1C1,CHMP7,RAB3IL1 |
| 9.143e-25 | -55.35 | GO_CELLULAR_RESPONSE_TO_STRESS | MSigDB lists | GO_CELLULAR_RESPONSE_TO_STRESS | 1467 | 365 | 17377 | 2626 |
MAX,ADD1,TMEM203,CXXC1,TMEM109,XIAP,CUL1,CCNB1,UBE2I,RBM4,PARK7,FBXO22,EEF2K,NEK6,DNAAF2,RAD23B,DNM2,FNIP2,CRY2,SEH1L,CDC5L,PLK3,BAK1,PGAP2,ERCC1,KLF10,AATF,MKI67,TOPORS,MCL1,RFC2,GINS4,STOML2,RAD18,RPS27A,AXIN1,PRDX5,MPV17,TFDP2,ZMAT3,PFKP,HDAC2,SSRP1,RECQL,CLSPN,MRPS2,POLR2K,SEC61G,MUM1,PRKAA1,EIF2AK4,PSEN1,JMY,LMNA,NPLOC4,WDR48,CNOT3,DDRGK1,MCTS1,TFAP4,RNF121,SMC3,MEX3C,INTS7,RIMS3,MSH2,TERF2,RB1CC1,MAN1B1,USP10,BCLAF1,ADRB2,MPG,MTR,RHOB,XRCC5,PI4K2A,FAS,PTPRF,SEC31A,DERL1,POLR2J,MDH1,CNOT6,MAP3K5,YY1,ZNF830,CDK2,RNF139,CDKN2A,EGLN1,DNMT3A,ATXN3,NQO1,RPS6KA1,CHD1L,PTTG1,RMI2,BCL2L1,INO80E,CRKL,MOAP1,TERF2IP,CCNA2,SHC1,SP100,KDM2A,ATP2A2,RALB,UCHL5,MTA1,UBA5,CDKN1B,CEP63,RNASEH2A,C8orf59,AQR,ATF2,RNF169,DCTN1,CDKN2AIP,ULK3,SEC61B,RFC3,BRD4,POLR2L,TAOK1,CRNKL1,POLR2D,DNAJA1,POLG2,TRIM28,SERP1,SUPT16H,ANKZF1,RAD51C,ALDH3B1,SEC61A1,NSMCE2,HIPK2,SEL1L,H2AFX,ATF6,PPP5C,GEN1,XRCC4,EYA2,CSNK1D,ATMIN,USP13,POLQ,BABAM1,CCM2,FLOT1,SDF2L1,BLM,ETS1,FOXO3,MAD2L2,NEIL2,RFWD3,RPA2,CCNK,PDCD10,SUV39H2,PTEN,HUWE1,CENPJ,PTPN11,GTSE1,ANXA5,COPS7B,CNOT6L,CITED2,GTF2H2,MSH6,TMX1,STAU1,TNFAIP3,POLK,NET1,PARP4,MRPS10,DDX39A,KLF6,POLR2A,PRDX1,SH3GLB1,RPA1,YIF1A,POLE,GPS2,PRDX3,TATDN2,TFDP1,PML,AEN,HMGB2,ASNA1,WDR76,CPEB2,DDB1,UBE2E2,THOC1,NF1,FAM129A,PPP1R15B,SLC29A1,SIRT2,UBQLN2,BECN1,MAPK14,MAP1LC3B,RNF103,FANCI,SSR1,MBD4,FANCL,PCNA,PIK3R2,XRCC2,RCSD1,TXLNA,AKR1B1,NDUFB9,KIF22,TCEA1,OGG1,CARM1,PTPRK,CDC37,COPS8,PLK1,TDP1,MIOS,RBX1,NCK1,SNRPB,RAD51AP1,VHL,TLK1,UBE2V1,BRCA1,PRKRA,SOX4,CHAF1A,TONSL,E2F4,CAB39,BAZ1B,STK11,CHEK2,COPS6,PSMC1,UBE2D3,TMUB1,NSMCE4A,DNAJB2,UFC1,CIB1,RHBDD1,DTL,XPA,TIMELESS,MDFIC,BCL2,ATP6V0D1,ZNF189,PREB,HP1BP3,POLR2I,ERLIN1,OXR1,GBA,EIF2AK1,MAP4K3,UBE4B,EIF2A,SYVN1,ISG15,RBM38,PSMC4,MASTL,PALB2,CDCA5,RUVBL2,ADNP2,USP7,BCCIP,FOXM1,XAB2,SUMO2,TMX4,SLC2A1,PMS2,RRAGC,IRF3,LYN,RPAIN,RAD23A,PDK2,MDM2,TARDBP,PDIA6,CTDSP2,HTRA2,PRPF19,PPIF,POLR2G,BTG2,PPIE,NFATC2,DCLRE1C,EDEM2,FANCE,RAD54B,DNAJC10,SCAP,TAB2,STAT6,ARNTL,WDR59,XRCC3,MAPK1,SMURF1,RAD51D,TMEM33,MIF,SLC30A9,MCM10,SH2D3A,TRIP12,SHPRH,DAP,EYA1,TMX3,MRPS26,SMC6,RMI1,DNAJB9,WRNIP1,SLC1A4,ARHGEF2,ATG13,RNF5,TXNL1,HMGN1,TMEM39A,HELB,PRKDC,TOP3A,MEN1,CHCHD6,HSPA1B,MAPK3,MTMR3,UPF1,PDCD6,NEIL3,COX8A,E2F1,PKD2,RBPJ,HRAS,IFI16 |
| 1.214e-24 | -55.07 | protein transport | biological process | GO:0015031 | 1348 | 343 | 17256 | 2622 |
CCDC93,TMED7,RAB14,NUP188,PDCD6IP,TSC2,TAP1,AP3M2,SYNRG,RIC1,PARK7,RPL23A,CDK5,NAPG,SNUPN,RABGAP1L,RAB4A,SRSF4,AP1M1,DNM2,AP2B1,NUP153,SEH1L,SRP72,PGAP2,USO1,TMEM115,ATG9A,AKT2,MCL1,NUTF2,ICMT,MCFD2,RAB22A,RAB2B,ARF4,PLEKHF2,HHEX,SMAD2,TMED10,RPS27A,RPS14,EIF2D,VIPAS39,ATP6V0C,BTF3,RRS1,ARRB2,NMD3,ZMAT3,LONP2,AAAS,NXT2,GGA1,SEC61G,RAB23,ACAP1,TMED3,PSEN1,VPS25,COPG2,NPLOC4,COPB2,ATG4A,SNX18,FBXO7,TNPO3,ATP6V0A2,MVP,CPSF4,SYTL3,NUP85,TMED2,SRSF11,NAGPA,EIF5A,TIMM8B,GCC2,RPS10,RPS24,SSR2,SRSF5,MTX1,TOMM40,PTTG1IP,GOSR1,RHOB,DERL1,SEC31A,SCARB2,KPNA1,NSF,PPP3R1,NUP58,SNX14,EXOC3,ANKRD27,NDC1,SARNP,SYS1,RAB11B,RAF1,GPR89A,ANK3,VTI1A,C5orf30,MYH9,TBC1D13,AP1B1,STAM,RAB21,AHCTF1,TBC1D22A,TBC1D14,NUP107,TNPO2,TAP2,ZC3H3,ATP6V1G1,SNX8,SEC61B,GOPC,RNPS1,POLR2D,RPL38,SLBP,ATP6V0A1,RAB1A,AP4E1,ERC1,SERP1,PEX5,CHMP4A,HSPA4,SEC61A1,VPS26B,RAB24,RPLP1,SEL1L,PITRM1,RPS2,SCAMP3,SRSF6,TRAK1,BTN3A1,IFT27,RAB11A,JAKMIP1,RPL17,ARF5,RPL19,UPF2,MTX2,PPP3CA,GUK1,DENND1B,DENND4C,RPL8,RABIF,RAB3IP,DDX39A,MACF1,RPL27A,YIF1A,KIF18A,HGS,RPL32,STX18,PML,YWHAH,GPR89B,IPO4,VPS29,SNAPIN,POLA2,MTX3,COPA,THOC1,SNX15,RBM8A,ALKBH5,UBE2Q1,AGFG1,RUFY1,SEC16A,SSR1,RAB8A,NUP210,RAP1A,TIMM23,EIF4A3,AP3S2,RAB35,ATG3,PIK3R2,RP2,TIMM50,CDC37,VPS13B,FYTTD1,LARS,TLK1,RAB5B,STX16,LSG1,OPTN,NECAP2,RPL37,TRAM2,TBC1D17,TIMM13,EIF4ENIF1,HSPB11,GRIPAP1,UEVLD,TIMM29,MIA2,ARRDC1,KPNA2,VPS4A,CLU,RPS26,ATP6V0E1,C2CD5,RPS15,TBC1D12,GORASP1,PHB2,CENPF,RPL15,RAB6A,XPO7,RHBDD1,NUP205,RINL,KIF13B,ARL6IP1,GLE1,LRSAM1,ATP6V0D1,PREB,KDELR1,RPL6,SYVN1,ZDHHC3,NPIPA1,RPL36,TSC1,GOLGA4,SNAP23,EXOC4,ZDHHC7,SIL1,NUP62,CTSA,CHMP2A,SNX27,CORO7,TOMM20,RPLP2,COPE,ATP6V1B2,LYN,RPAIN,BCAP31,RPL11,HNRNPA2B1,ATP6V0B,ANKLE1,SAR1A,AKAP8,BCAP29,SCAMP4,AHCYL1,CLTB,CHTOP,LMAN1,CHP1,SNX25,RPL29,NXT1,RPL35,PPT1,RAB7A,NUP155,BICD2,ERBIN,CHMP2B,RPS9,RHBDF2,RPSA,SRSF1,SURF4,VPS26C,TOMM6,TIMM17A,ARNTL,AP1S1,CHMP4B,SMURF1,AP2S1,ABCA1,PARD3,CDC40,GOLPH3L,RAE1,NUP54,VPS45,ARFIP2,TIMM21,ARF1,GGA2,AP3S1,TFRC,KLHL20,SEC24C,RRBP1,ARHGEF2,STAT3,CAMK2G,MYO5A,TGFB1,ZDHHC18,NASP,SNX2,SCFD2,COG1,SYMPK,MFN2,RAB18,SEC23IP,UPF1,ATP6V1D,PDCD6,KPNA4,GOLGA7,SNAP29,RBPJ,SPCS3,SRSF3,ATP6V1C1,CHMP7,RAB3IL1 |
| 2.480e-24 | -54.35 | desmoplastic | COSMIC cancer mutations | desmoplastic | 15212 | 2411 | 17385 | 2587 |
HECA,ZBTB10,ABCC10,HEXB,CCNL2,FBXO22,EEF2K,RAD23B,ATP13A3,DNM2,ZNRD1,FTSJ3,USP34,CCDC57,ERCC1,NRAS,EHMT1,KIF15,HNRNPF,WDHD1,MIER2,DIDO1,MCM2,RAB22A,SMAD2,MID1IP1,RPS27A,MPV17,COX5A,SMAD1,ZNF75A,ANXA11,SLC25A33,SEC61G,GGA1,MUM1,CCZ1,TRIO,CUTA,RAB23,KCTD17,HAUS4,EIF2AK4,APH1B,PARN,CDC73,MYL6B,ATG4A,TMEM179B,PDXP,SMC3,MVP,NSUN4,PPA1,IFRD1,AGGF1,FOXK1,RBM42,GTPBP4,MAP7D1,MRPL16,ELK1,EIF4H,RDH11,MAGED2,KPNA1,ETS2,TYW5,WIPI2,RUFY3,PDLIM5,ACSF2,RHOG,EXOC3,STARD7,C5orf30,VTI1A,SLC35B2,INO80E,LCLAT1,RCOR3,CPNE3,KIAA1147,RBM23,ZNF420,AHCTF1,TBC1D22A,TBC1D14,GMEB1,NSFL1C,SEPT11,GPD1L,ZC3H3,ARL5A,PDCL3,SNX8,ERMP1,EID1,IDH3A,POLR2D,HTATIP2,MEF2D,TMEM147,GSTCD,TANC1,MAT2A,VPS26B,NSMCE2,CORO1C,CAMKMT,PPP5C,PITRM1,TUBB,COMMD10,ZNF445,SRSF6,HABP4,CCM2,FLOT1,BTN3A1,ATG2B,ABHD14B,PPP1R3B,GOLM1,ZBTB45,HUWE1,ZNF260,NAA50,ANXA5,LTN1,UBE3B,NAP1L4,ZNF710,ST8SIA2,MED22,SPTAN1,STAU1,TCTEX1D2,DDX24,TACC1,MRS2,LDHA,HEBP2,LLPH,RAB3IP,TTC33,PICALM,SH3BP5,SLC19A1,ACOX1,FAM3C,AEN,PARP10,YWHAH,GPATCH4,FAM129A,TRIM11,YTHDC2,SNX15,RBM8A,ENSA,NENF,SND1,RUFY1,TRIM65,ZER1,PRNP,KRR1,RAB8A,NT5DC1,NOC2L,EIF5,TACC3,VPS13B,PTPN18,MIOS,SNRPB,MBLAC2,CDC6,UTP3,PBRM1,USP21,TRAM2,FBXO28,BCL7C,ARRDC1,ADAM9,DVL1,ZNF564,FUBP1,C1orf74,CTU2,PARP12,ZCCHC9,CENPF,LAMTOR3,CHCHD2,NCKAP1,LYRM2,RSAD1,TNS3,SUB1,RINL,SSBP3,MBD2,XPA,AHCY,RBM3,GLE1,LRSAM1,HDHD2,NTPCR,NSDHL,AMD1,CAMSAP1,ZNF761,METTL22,ICAM2,STYXL1,APPL1,BBS12,ANKRD46,RXRB,SDHB,PCM1,GALNT2,TMEM168,NLRC5,RUVBL2,MYO9A,BTBD10,CCNB2,USP7,GLT8D1,RPLP2,SUCLG1,ARID2,TMX4,SLC2A1,ATP6V1B2,PCBP1,LYN,BCAP31,VAV1,TMEM69,MRPL50,PSMA6,ZNF473,BRPF3,TARDBP,BCAP29,CTDSP2,PRPF19,PPIF,KDM3B,MND1,CLCN3,BIRC3,RAB7A,ANKRD33B,PPIE,CHMP2B,VDAC1,EIF3H,TMEM201,GLOD4,IDE,DHX16,UHRF2,CHMP4B,XRCC3,PARD3,BCL2L12,MCM10,C19orf53,KLHL21,PDAP1,CDCA8,TMX3,ARF1,SLC12A9,TUBGCP2,DNAJB9,HOMER1,POLR1B,RNF5,RBM15B,PPAN,RHOA,RPRD1A,BTAF1,TOP3A,ARHGEF12,PCGF1,DDX23,RAB18,CACNB1,PDCD6,ATP6V1D,L3MBTL3,FAM110A,NEIL3,CTBS,BBX,IMPDH1,TAF12,NR2F2,PGAM1,HIPK3,IFI16,TXN,H2AFZ,PNISR,TMEM203,PRKCSH,USP39,UBE2I,PARK7,SLC25A37,ASPHD2,ZNF428,RAB4A,TRA2B,SUCLG2,TAF5L,CISD2,SMARCE1,ZNF800,CDC5L,ZNF524,SGCE,NSUN2,USP22,CLNS1A,EIF3A,ZMYM3,DOT1L,IWS1,ANKRD10,WAS,KIF18B,TPP2,C1orf109,ZMAT3,B4GALT2,PRPF38B,RECQL,C9orf78,EWSR1,GADD45G,RRM1,ACAP1,B4GALT1,CYCS,FAM136A,SUPT7L,TMEM165,CNOT3,NPLOC4,SPAG5,WDR48,RTKN,CEP104,EXOSC7,KLHL5,LRRC8D,PPP4R1,MSH2,PIGG,FBXL7,MRPL40,SYTL3,FAM171A1,APOL1,EIF5A,GCC2,PRIM2,ELL2,RDH10,MFNG,RPS24,GORASP2,CAPZA2,ADRB2,CCT8,MTR,PHF6,PFDN5,SLCO4A1,TTC13,GOLGA2,RBMX,MED15,PIAS2,APPL2,SAMD8,NUDT3,CDKN2A,ZNF511,ATXN3,RAF1,KIAA0232,C2orf49,CD320,EPM2A,CCNA2,MTMR4,BRI3,TP53BP2,AQR,RBM12B,ILKAP,CDK12,SAP30,BRD4,DRAP1,NARF,LRRC8A,ELP4,ABHD11,PKMYT1,ASB13,SERP1,TRIM28,SUPT16H,EIF3K,CHMP4A,CBWD1,ATF6,XRCC4,PRPF4B,ADAM23,NDUFS1,DEPDC1,MECP2,SECISBP2,HMG20A,WWP2,JAKMIP1,SLC25A36,DNAJC8,AXIN2,CITED2,JMJD4,ANKRD37,KAT2A,TMEM126B,RABIF,ADSL,BMS1,KCNQ1,ARSK,MACF1,KIF11,COMMD4,KLF6,SMAP2,FADD,SH3GLB1,MYO1F,CBX3,TMEM127,INF2,PPP1R11,DUSP11,DDX5,WDR62,TAF6,ESPL1,PURA,DDB1,DEF6,IPO4,FAM83G,UBL3,PIGM,NAT9,LYRM4,GPR132,UBE2Q1,PTP4A3,BRIX1,MRPL19,ZNF696,SF3B2,PCYOX1L,CDC42,SYNM,GOT2,JAZF1,HADHB,RPF2,SLC35C2,CNNM3,CARM1,SRPK2,WDR41,LARS,ZCCHC10,CCDC138,LRBA,SUMF2,KMT2C,PRPSAP1,ASF1B,RPL37,MAN2A2,EIF4ENIF1,NIP7,U2SURP,MIA2,ZNF268,ATP6V0E1,PPP1R2,PM20D2,XPNPEP3,RGS2,LYAR,FAM89B,POLR2I,TRAFD1,SUGP2,GBA,SYVN1,DAPK3,ARHGAP15,MASTL,UAP1,NFIL3,FN3KRP,YWHAZ,CTSA,TMEM14A,TOB1,TSEN15,ADNP2,TCF12,PRKAB1,MDH2,SMARCA4,RRN3,UBXN2A,IARS,CD3EAP,KIF14,EXOSC1,CS,CLTB,DNAL4,CSTF1,POU2AF1,UBQLN4,HPDL,PGGT1B,SELPLG,SMU1,ATXN1,GLO1,OGDH,BICD2,CADM1,EDEM2,HERPUD2,TOLLIP,FANCE,MBD3,PDHX,RPS9,ALKBH6,SURF4,DUS3L,ARNTL,ANP32E,FKBP5,TMEM101,CCDC125,ABCA1,PDCD2L,GCLM,RAE1,DCTN2,CHIC2,PAWR,MXD4,DCUN1D4,PIP4K2A,XPR1,FERMT3,KIF5B,KLHL20,SEC24C,RRBP1,ARHGEF2,LDLRAD3,STAT3,MYO5A,NIPAL3,AMPD2,TXNL1,PHF20L1,DCAF6,FAM49B,TMEM39A,ATP2C1,RFFL,COG1,RCOR1,PRMT2,TFEB,LEMD2,UPF1,ELMO1,ZC3H7B,DTX4,ZMIZ1,TERF1,HRAS,CCDC93,FGFR1OP,TMED7,PIGQ,AGPAT1,CNTROB,PPP1R16B,MIS12,GSDMB,TTC9C,PDS5B,SENP1,PGAP2,TMEM115,PLEKHM3,DCUN1D5,PLEKHF2,BRMS1,PWWP2B,TRIM47,WDR11,AXIN1,SMG9,TRIM52,LONP2,NDUFV2,PHF23,CERK,SLC4A2,EZH1,ITGB5,LMNA,FBRS,MCTS1,DDX56,EIF2S2,SLC38A5,FOXN2,CARS2,PRRC2A,C16orf72,RB1CC1,ZMYND11,PGS1,MYBL2,UHRF1BP1,SRSF5,MPG,MATR3,CYB5A,NCDN,POLR2J,SETD3,PTAR1,CNOT6,NDE1,EGLN1,ZNF207,ANKRD27,ABCA3,SARNP,IVNS1ABP,MON1B,RMI2,TMEM97,NIT2,NUF2,ZNF267,TCF19,TMEM161B,KTN1,APP,PRKD3,CLUAP1,ATP2A2,UTP18,DUT,ANAPC7,RNF19A,FAM76B,CLN6,TMEM9,GCC1,RNF169,ADCY7,ATP6V1G1,ENPP4,RNPS1,CDCA2,FKBP3,GPR137,DDX17,CHCHD3,PEX5,CDC16,HIPK2,MBOAT1,TICAM1,PDXK,ZBTB11,TMBIM4,GMCL1,UBE4A,IL21R,ETS1,WRB,ZNF92,PNO1,CAPN2,ADD3,SUV39H2,TTLL12,TPCN1,TMX1,LYPLA2,HNRNPM,LDHB,PPP3CA,NUDT8,POLK,JTB,EMP3,MTMR12,ZP3,PDE3B,KIF18A,CCDC6,WNT5B,MAPK6,LY75,C4orf46,SLC25A19,RGL1,PSAP,WDR76,IGBP1,FAF1,SNAPIN,COX15,AGRN,THOC1,GNPDA1,GPBP1L1,PPP1R15B,CSNK2A1,EBNA1BP2,GIT2,BIRC2,ATPAF1,DLG5,ABL2,XRCC2,ZFYVE27,MCMBP,PTPRK,CDC37,METTL1,SP3,EXOSC6,HARS,GMFB,ESYT1,ANLN,RAB5B,RHEB,DPYSL3,TBC1D17,TIMM13,CDCA4,TONSL,NRM,NAGLU,ACTB,ZNF45,TMUB1,CTCF,ASAH1,DOCK11,CRLF3,ASXL2,LRRC14,SLC27A4,AFF1,MDFIC,MAML1,CYTH1,NQO2,UTP15,EIF2AK1,EIF4G2,ZDHHC3,MOSPD3,ITPRIPL1,CDC27,SNAP23,TBPL1,PRMT7,KCTD7,NDUFA5,CYLD,UGP2,DYNLL1,COPE,HCFC1R1,ZADH2,GGPS1,RPAIN,RAD23A,SEC11A,PDK2,ATP6V0B,STRBP,TNFAIP8,DUS4L,MRPL34,PDCD2,SAP30L,SLC39A9,CLPTM1,RPL29,RPL35,BTG2,DNAJC9,MTMR6,FRAT2,NFATC2,KDM1B,ARL5B,USP36,CCDC127,MRPL2,ATP1A1,CLK3,PSMD3,MAFK,CEP55,NDUFA11,DNAJC17,ZNF436,NCOA1,SLC25A39,ZC3HC1,ZNF146,ATXN7L2,CDC40,GOLIM4,SMAP1,RRP15,DAP,GNE,SMC6,ARFIP2,NKRF,CHAC2,BZW2,WRNIP1,SS18L1,CENPM,PTGES3,CAMK2G,MLEC,ZNF202,PPWD1,FAM50B,RHOT2,NEU1,TPD52L2,GOLGA7,TWSG1,PGRMC1,GLG1,FAM126A,SPCS3,RPS6KC1,UBE2C,PPCS,NDUFB6,TMEM41B,ZDHHC8,PLXNA1,CCNB1,SLC20A1,COMMD6,ABHD14A,POLR3K,C14orf119,ASAP2,SNUPN,CNPY4,TFG,PLCL2,SEH1L,ATG9A,PBK,MKI67,DDX20,AMDHD2,SLC17A5,GALNT7,CCNF,FOXRED1,RBM47,PTER,WDR4,DHTKD1,TRAF5,HDAC2,PWWP2A,HSPH1,LIME1,MAPRE1,CHTF18,ADO,KIF23,SLC35B1,NOTCH2,PMF1,JMY,FKBP1A,SLC31A1,SNX18,ATIC,ATP6V0A2,PIKFYVE,RNF135,LPCAT1,EEF1D,TMED2,FTL,PHF10,DDX28,ZNF84,SIGMAR1,PIP4K2C,RIT1,PLEC,KDM3A,SF3A2,FAS,EPRS,ZNF777,TMEM54,QARS,PPP3R1,TCOF1,CABLES1,NRBP1,DNMT3A,RWDD1,CKLF,TRIP10,SF3B1,SUZ12,CAST,RAC1,GPR89A,GNB2,FLAD1,APLP2,KDM2A,TNPO2,CDKN1B,TALDO1,GPX4,ATP13A1,RFC3,MAPRE2,ERF,CUL3,SLBP,KIAA1586,H2AFV,GAR1,PSMB9,POLG2,DHX57,NSA2,HSPA4,MRPL55,JAK1,TBL3,SEL1L,H2AFX,KLHDC4,B4GALT3,PDCD11,ATMIN,POLQ,POU3F2,NCOR2,ANKRD13D,PKP4,SCAMP3,CDCA3,SLC25A12,BLM,TMCC3,GTF2F1,CRAT,AHSA1,PRC1,UPF2,COPS7B,SLC38A10,CNPY3,UBE2M,IFT46,TMEM160,TSHZ1,ZFP64,DENND4C,DENND1B,WDR18,RPL8,ILF3,LRRC1,RHOT1,MARK2,TSR2,ECH1,PRDX1,PLD3,NUCB1,FBXO21,GNA12,C1orf131,PRDX3,PFDN4,HNRNPH3,STX18,TFDP1,KHSRP,ASNA1,CPEB2,SSSCA1,BYSL,VPS29,S100PBP,MIB2,IER2,PTMS,NOP2,UBN1,DCAF15,NF1,FLYWCH2,ALKBH5,MOGS,TAF6L,MAPK14,BECN1,SNAPC4,RNF103,BCAT2,MBD4,C18orf32,METTL14,ZNHIT6,IMPAD1,RCSD1,PHTF1,SRI,KIF22,ZBTB22,NFU1,TRIM14,ELOF1,COPS8,FYTTD1,TRIM8,RRM2,SOX4,ABHD5,UBTF,CXXC4,UEVLD,SPATA2,PQBP1,IARS2,ATXN2L,GALNT10,STARD3NL,RPS15,PIGN,AGTRAP,CIB1,XPO7,SRRT,ZNF449,CAPZA1,GLTP,KIFAP3,BCL2,N4BP2,HP1BP3,THNSL1,ISG15,CAND1,GNAS,TSC1,RBM25,CDCA5,ZFP90,NANP,RBBP4,ZBTB24,SMARCD1,MBD1,WASF2,MMACHC,TOMM20,IFI27L1,GNPNAT1,MPHOSPH8,HNRNPUL2,CHD1,MEAF6,C2orf68,CCDC50,AKAP8,PARL,RPN2,CHTOP,FAM3A,F2R,TMEM14C,SCYL3,ABI1,HTRA2,MOSPD1,RLIM,FAM172A,ZNF500,PSMB7,NLN,WIPF1,BUD13,NDUFB1,PEF1,EIF3G,BTBD1,TAB2,CHCHD1,TULP3,WDR59,CANT1,SCARB1,GAS2,USP11,SMURF1,PPP2R2D,TSPAN5,CDS2,MAGEH1,MRPL42,EYA1,CDK2AP2,MRPS26,LETMD1,KLF13,HDDC2,RGS1,MAN1A1,FBXO5,GART,PELO,TANK,BRD7,MRPL11,SAMD4B,ZDHHC18,GTF3C6,POLR3GL,WDR81,MEN1,ZNF407,MFN2,COX8A,ZRANB2,MBD6,SRSF3,ATP6V1C1,IDH3B,TATDN1,TSC2,LACTB2,CMTM6,RBM4,ZNF275,ANKRD39,RPL23A,CDKN2C,USF1,MECR,AP1M1,UPRT,CRY2,ECD,RNF26,TIPARP,LRRC59,ANKRD9,RHBDD2,MGAT5,BAK1,ZNF559,RHOBTB3,GABPA,WBP1,ARF4,GINS4,KRIT1,BOLA3,AHNAK,RAD18,PDRG1,RNASEL,CHPF2,SMNDC1,PDCD4,HIVEP3,KIAA0100,CLSPN,RHOC,DHX9,PDCD7,PSMD9,HAUS2,COPB2,TFAP4,CD59,RNFT1,RIMS3,MEGF8,EFTUD2,FBXO7,CPSF4,MRPL21,PHKG2,LUC7L2,SRSF11,EIF3L,MTA2,TYW1,ITM2A,SSR2,BCLAF1,MTX1,SFXN5,FNTA,PDLIM1,TXNDC16,ZNF830,TMEM159,MRPL3,ALS2,FAM72A,TRIM41,KARS,NQO1,POC1A,ANK3,PTTG1,TPX2,TBC1D13,DAZAP2,STMN1,GLRX3,REPS1,ABHD16A,FBXL6,SH3BP1,MTA1,UBA5,CLCN6,INTS12,C8orf59,RPRD1B,CGGBP1,CPNE1,SEC61B,POLR2L,FAM118B,GOPC,E2F3,CIRBP,RPL38,CRNKL1,PFKFB3,GORAB,RAB1A,GIGYF1,TMEM184C,PPP2CA,KIF2A,CCDC14,LSM6,RNF38,SNRPG,DMWD,USP13,MZT1,ZFP91,TRMT6,IP6K2,WDR5,SLC25A43,IFT27,PMVK,NEIL2,RRP36,SRXN1,RPA2,PSMD2,CLIC4,PDCD10,CBWD2,COQ4,ITGB8,ARF5,ARHGEF1,FBXL19,TTPAL,UTP20,GPS2,DBI,SSNA1,MRFAP1L1,CD81,TMEM131,WDR13,FANCI,CREM,FANCL,GLIS2,IL6ST,POP7,SLC44A1,MTPN,ASB6,PLK1,RPP25,SEPT9,CELSR2,RBX1,APH1A,RAD51AP1,CKAP2L,PSMG1,UBE2V1,EAF2,IL12RB1,KRTCAP2,LUC7L,LSG1,NECAP2,C1orf122,TRIM4,AGPAT2,CHD3,ZNF367,E2F4,PRPF4,BEND6,CLN3,DNAJC30,NGLY1,POT1,MYL12B,CCDC137,RMND5A,HJURP,PHB2,DNAJB2,FAM53C,NKD2,SDC2,KLC1,CDK13,ADCK5,COX4I1,DNAJB1,RAB6A,ARID1B,C1GALT1,MLX,UBE2Q2,CCP110,ZNF746,ARL6IP1,CTR9,NIPSNAP1,ABHD2,DCAF8,ACSL3,LDB1,MAP4K3,ARMC8,NMT2,IRF5,RPL36,HAUS8,MBIP,COX7A2L,ZDHHC7,SIL1,FAM122A,DTD1,UNC13C,BCCIP,SART1,TRAF7,NDUFAF2,TOR1AIP1,ZNF416,LAGE3,TM9SF3,ZFYVE21,RRAGC,ZNF121,NRF1,WDR44,PIN1,EFCAB11,RPAP1,CABLES2,LMAN1,AHCYL1,TOP1MT,STRAP,SPSB3,ZNF583,SNX25,ARHGAP17,POLR2G,ZNF780B,PPT1,DCLRE1C,MRPS14,RHBDF2,SUGP1,RBL1,FASTK,UBXN2B,STK38,AP1S1,SPRYD4,SLC22A23,H3F3A,CHID1,SMAD4,RAD51D,SLC30A9,UNK,CMAS,NADSYN1,HMGN3,NCAPG,SCYL2,FZD6,HERC3,GTPBP3,CTSS,RNLS,YTHDC1,ACP2,HMGN5,CSRP1,METTL5,ABCF2,TUFM,RANGAP1,PNPLA8,HAGH,API5,ZFR,SEC23IP,E2F1,TMEM219,USP20,RBPJ,PDCD6IP,MAX,LUZP1,GXYLT1,ADAM10,CXXC1,TSC22D3,AP3M2,CUL1,GYG1,NANS,MYEF2,ANKRD26,NOL11,FIZ1,ZNF200,MARCH2,SLC26A2,SRP72,KLF10,LACTB,RFC2,CBFB,RAB2B,MAP3K4,HHEX,LUC7L3,RPS14,MAP4,MRPL27,BTF3,PTPDC1,NMD3,CCDC59,PTOV1,COX5B,DNAJC5,SCOC,DHPS,POLR2K,ANKH,C16orf87,VAV2,GSPT2,TATDN3,DLGAP4,PXMP2,PRPF39,PSEN1,ZNF79,PDXDC1,VPS25,NDUFS7,YY1AP1,C12orf10,FAM192A,RPN1,LHX8,ARPC5,ZNRF2,TPST1,DAPK1,PIK3IP1,CYC1,SOCS5,FDFT1,PIGT,EMB,WDR1,ZNF574,C1orf35,EXOSC9,ARID1A,PTTG1IP,C9orf40,FXR1,GOSR1,TWISTNB,AKAP1,XRCC5,HMGN2,PI4K2A,CAT,DERL1,MTHFD2,HSPBP1,ARAP1,USP32,FAM83D,CABIN1,SMPD4,GPI,CYTIP,TP53RK,REPS2,RAB11B,UROD,SLC39A13,POMP,BCL2L1,NUDT19,DECR1,RALB,SIAH1,ADCY9,LPIN2,MRPS27,SOCS6,TTC3,RNASEH2A,CFL1,ANKLE2,CDC123,VDAC2,EDF1,EML4,ERC1,AMZ2,ANKZF1,ZNF282,DSN1,DDOST,HINT1,DGCR8,SAFB,HAGHL,FTSJ1,RWDD4,LMBR1,NCLN,BEND3,EYA2,DYNC1LI2,MANBA,SLC41A1,B4GALT5,FAM76A,TKT,CBLL1,ARGLU1,LANCL1,POFUT1,FAM8A1,HEATR5B,HLA-A,EBP,RFWD3,NDUFA2,FUT8,BTF3L4,PTPN11,MRPL54,FEM1B,RPL19,CNN2,NDUFA3,MTX2,MSH6,PDLIM2,LONRF3,RFXANK,FBXO9,GUF1,RPL32,ZHX1,NDUFS5,WDR91,HIGD2A,GPR89B,ZBED3,RORB,POLA2,ZNF76,COPA,UQCR10,HMGXB3,ABCB10,COMMD5,MAP1LC3B,DST,RAB35,SIVA1,GPATCH1,DRAM2,DEAF1,SNRNP200,LAP3,NCK1,VHL,SREK1,ARHGDIB,PITPNB,HSPB11,BRWD1,PPM1G,SH3GLB2,CRCP,BAZ1B,CAB39,ACBD4,STK11,CLU,CHEK2,ZSWIM3,TSTD2,MRPL13,CHPT1,DCAF5,CAPN1,UBE2D3,NSMCE4A,PPP1R12A,ZCCHC8,GORASP1,UBXN1,NACA,RPL15,PCSK7,THRAP3,QSOX2,TTF1,PRPF18,CHKA,DTL,MED10,ZRANB1,MCPH1,SLC12A2,ATP6V0D1,CSNK1G3,CREG1,NUDT4,RPL6,VKORC1,SLTM,EVC2,KLHL15,SIAH2,SLC16A1,EHD4,SNRNP70,C11orf1,APOL2,N4BP2L2,SNX27,CHMP2A,CORO7,FEZ2,UCK2,PMS2,UCK1,CLCC1,EXT2,MXD1,USP5,HNRNPA2B1,SAP130,NVL,PPP6C,CYB5R1,ZNF770,EBAG9,RNF25,PCGF6,METTL2A,FAM72B,PON2,HNRNPR,HPS5,STAT6,MAPK1,BRD9,TMEM33,NAT14,DNAJC2,TRIP12,SHPRH,SCYL1,VPS45,GFM2,SPPL2A,FASTKD3,FGFR3,MZT2A,PPIG,ZDHHC13,TMEM99,H2AFY,NDUFS8,ATG13,ERI3,FBL,FRMD8,SLC35A1,MICAL3,TGFB1,B3GALT6,ELOVL5,HEMK1,TIMMDC1,HELB,PSPC1,MIER1,SCFD2,NDRG3,MTMR3,ACAT1,CENPT,PLOD3,RAB3IL1,RAB14,ADD1,KDM4A,MRPS15,XIAP,DHX8,GLUD1,ANKRD23,CDK5,CALM2,PSMD1,NEK6,NSRP1,RABGAP1L,SRSF4,FNIP2,KCNAB2,PCBP2,PLK3,ZNF672,HSDL1,MRPL43,TOPORS,MCL1,PPFIA3,SMC2,ICMT,SLC50A1,STOML2,LIMK1,ZNF689,PRDX5,ATE1,MLYCD,ST3GAL2,ATP6V0C,FBXL3,TFDP2,E2F2,PFKP,AAAS,DDX42,SSRP1,MRPL9,MRPS2,STRN4,TOP2B,ZNRF3,TMED3,DDRGK1,RAVER2,GNS,INTS7,INPP5A,MCM5,PHF14,ZNF326,NAGPA,TIMM8B,ETV3,TSPAN31,DHX29,TEX10,MAN1B1,RPS10,CBFA2T2,ABCF1,RHOB,LRRC14B,DTWD1,PTPRF,SCARB2,CCDC86,DUSP3,SLAIN1,MDH1,HEXA,RNF139,SNX14,ZNF296,TRERF1,UBR2,CHD1L,ACTR3,WDTC1,MYH9,CREBL2,NIPA2,PRKACA,SAFB2,STAM,ARL6IP6,RAB21,SP100,ZKSCAN1,DDA1,ANKRD13C,MAVS,CEP63,TMEM136,ATF2,RBM15,DCTN1,SHOC2,PSRC1,MAP4K4,WBP2,ATP6V0A1,NDUFA7,DNAJA1,TAZ,TAF2,SEC61A1,RPLP1,WDR7,CBLN2,RBMS1,FUS,GEN1,LRP8,COIL,LRCH1,GALK1,RPS2,SESTD1,TRAK1,JMJD6,SIKE1,AKT1S1,KRI1,FBXO3,ERH,GATC,PPP1R8,PRDM4,GTSE1,GEMIN6,DCP1A,SGCB,S100A6,IMPA2,NUDC,PDPK1,TK1,GUK1,TNFAIP3,GALC,ZNF512,KIAA0930,MRPS10,DDX39A,RPA1,ZNF862,ZNF180,KEAP1,POLE,TATDN2,PITX1,CAPN7,LRPPRC,PML,HMGB2,USF2,ANAPC4,SRM,DDX47,MCCC1,CDC42SE2,S1PR2,CDIPT,KCMF1,SSR1,LIN9,PCNA,ZNF639,TRMU,ETV6,PIK3R2,PPCDC,TXLNA,FAM86C1,MYBL1,MRPL32,CCAR1,ABCC5,PBXIP1,TLK1,MRPL12,EZR,LNX2,LRP5,BRCA1,PRKRA,STX16,EPB41,SEPT1,SOCS4,QRSL1,GLCCI1,NUDT11,GEMIN7,LZTR1,RACGAP1,PPP3CB,B4GALT4,RLF,RAPGEF6,SNRNP25,RB1,VASP,MED8,VMP1,PPIL2,MEA1,TIMELESS,AHDC1,ALDH18A1,TMEM8A,ABCC1,PREB,TRAPPC9,AACS,MEMO1,KRAS,RTF1,UBE4B,NFATC2IP,LY6E,ARPC1A,ZNF174,PSMC4,GOLGA4,SYNCRIP,PRPS2,NIPA1,TIGD2,RNF114,FOXM1,MRPL39,XAB2,DUSP22,COMMD8,RPL11,CSDE1,MDM2,CORO1A,METTL9,MINPP1,POC5,DVL2,GM2A,PSMA8,COQ10B,CPOX,TIGD5,SLC26A6,CYP20A1,PRPF3,TXNL4A,RPSA,SRSF1,DNAJC10,ZNF700,SCAP,PLEKHG4B,TIMM17A,FAU,LTA4H,AP2S1,USP53,CTDP1,MIF4GD,CDT1,ARID5A,SUMF1,GGA2,AP3S1,CSNK1A1,RMI1,TFRC,PTPN2,STARD9,IRF4,GSTK1,NDUFV1,SLC1A4,CWC27,SLC35B4,DDX31,ABCD1,RPAP3,CNTN5,SNX2,ZMYM5,CCDC34,CHCHD6,BSDC1,KPNA4,CDKN2AIPNL,FBXO41,BIRC5,TFE3,SNAP29,CDCA7L,PKD2,ACADM,CHMP7,SAT2,GCSH,ZNF496,TMEM109,TAP1,NHLRC3,IKBIP,EIF1B,ELMOD2,KIFC1,DBNDD1,RNASEK,CDC25B,PRADC1,DNMT1,NOL12,USO1,AKT2,NOL8,GNG7,AURKB,MCFD2,SLC25A5,ZFAND5,MAK16,STT3A,TMED10,PSMD8,EIF2D,ITGB1,PTPN7,UQCRH,RRS1,ARRB2,RTN3,SVIP,DDX58,WSB2,PPIB,MUT,GMFG,HLA-E,NDUFA4,MAN2B1,METTL3,CFLAR,NDUFS4,RNF121,MEX3C,KLF16,HDAC7,DAD1,BDH1,PCYT2,GNAI2,ANKHD1,TERF2,MORC3,KCTD20,SEPT8,DCTD,TOMM40,ADSS,SERTAD2,SERF2,ZFP92,NSF,DCK,ERGIC3,ACLY,LPCAT4,VCPIP1,YY1,MAP3K5,PPP6R3,PPP6R2,RNF14,CDK2,ZC3HAV1,SYS1,ZBTB37,URB2,EIF3D,MAGED1,KLHL18,ADPGK,SLC25A44,AP1B1,SDHA,PHC2,CRKL,TERF2IP,MOAP1,CYHR1,ZNF75D,SHC1,UCHL5,NAA35,TMBIM1,CCT2,CDKN2AIP,MKLN1,GALK2,CDC23,SHCBP1,AP4E1,PRDM11,VEZF1,PPP2R5A,ACYP1,STAT1,PPA2,TRIM32,RHEBL1,C1orf112,MRI1,TCF3,BRAP,AGPAT3,MYNN,SDF2L1,SPR,RAB11A,REEP5,FOXO3,MAD2L2,CCDC28A,PIP5K1C,RBM17,MAT2B,PTEN,CENPJ,TAGLN2,CREB1,SMC4,RNASEH2C,NEK7,NET1,PARP4,TBRG4,ANAPC2,RPL27A,YIF1A,SGSH,HGS,TTLL4,SLC38A7,MFAP1,CCDC69,BRWD3,ESYT2,SKA3,NPHP4,UBE2E2,HNRNPAB,PLXNC1,TMEM184B,ST13,DNAJC24,ZNF107,SLC29A1,KIF2C,AGFG1,SIRT2,FKBP2,USP48,SNRPD3,UBQLN2,CUTC,EDC3,UBLCP1,ZNF804A,RAP1A,THADA,EIF4A3,AP3S2,ATG3,DPYSL2,PPP1R12C,AKR1B1,NDUFB9,JOSD1,RP2,TTC4,TECR,ARID4A,FGFR1OP2,TIMM50,TDP1,DPM1,FOPNL,SLC16A7,WDR82,SLC25A22,STK17B,DHX15,CHAF1A,GEMIN5,COPS6,SASS6,RPS26,PSMC1,SLC12A7,TBC1D12,TM9SF4,ZNF768,UFC1,MED13L,TIA1,MEF2A,EPHX2,PITHD1,RHBDD1,NFATC3,BANF1,ZNF335,BUD31,YBX1,KNTC1,ACAD8,UBE3C,ZNF189,ALDH9A1,KDELR1,TSTA3,CIC,PSMA1,NAP1L1,EXOC4,KIAA1328,PITPNA,NAA20,PTDSS1,MZT2B,PDSS2,C7orf26,TMEM106C,IMMT,ASH1L,CHERP,WDYHV1,PLAGL2,CHKB,IRF3,TWF2,ANKRD28,FARSA,SAR1A,APOOL,PDIA6,ACSL5,TOR1AIP2,AZI2,GFER,RAD54B,DAP3,TMEM41A,ZNF317,GADD45B,AKNA,REEP4,CBX4,MIF,KIF3B,GOLPH3L,SH2D3A,CASP6,TOR3A,SRGN,DBF4,MFSD10,SAC3D1,CTNNBL1,YIF1B,CLDND1,TTC17,SLC25A1,GINS1,CSNK1G2,TELO2,ADAM17,HMGN1,NASP,ASPM,PRKAR1B,SYMPK,TARS,SNRPA,MAPK3,HSPA1B,HLA-B,ATAD2,PLAA,ZNF330,KBTBD7,PREPL |
| 2.609e-24 | -54.30 | GO_CELLULAR_RESPONSE_TO_DNA_DAMAGE_STIMULUS | MSigDB lists | GO_CELLULAR_RESPONSE_TO_DNA_DAMAGE_STIMULUS | 657 | 200 | 17377 | 2626 |
UBE2E2,THOC1,TMEM109,XIAP,CCNB1,UBE2I,MAPK14,FANCI,MBD4,FANCL,PCNA,NEK6,XRCC2,RAD23B,FNIP2,CRY2,KIF22,TCEA1,OGG1,CARM1,CDC5L,PLK3,PLK1,BAK1,COPS8,PGAP2,TDP1,ERCC1,AATF,RBX1,RAD51AP1,TLK1,TOPORS,MCL1,UBE2V1,BRCA1,SOX4,RFC2,GINS4,CHAF1A,RAD18,TONSL,RPS27A,E2F4,BAZ1B,STK11,CHEK2,COPS6,TFDP2,ZMAT3,SSRP1,UBE2D3,RECQL,NSMCE4A,CLSPN,POLR2K,MUM1,CIB1,PSEN1,JMY,CNOT3,NPLOC4,WDR48,MCTS1,DTL,TFAP4,SMC3,INTS7,XPA,MSH2,TIMELESS,BCL2,TERF2,POLR2I,USP10,MPG,RBM38,ISG15,XRCC5,MASTL,PALB2,POLR2J,CDCA5,CNOT6,RUVBL2,YY1,ZNF830,CDK2,USP7,BCCIP,ATXN3,FOXM1,XAB2,SUMO2,CHD1L,PTTG1,PMS2,RMI2,IRF3,BCL2L1,INO80E,LYN,RPAIN,RAD23A,MOAP1,TERF2IP,MDM2,CCNA2,SP100,KDM2A,UCHL5,MTA1,CDKN1B,CEP63,RNASEH2A,AQR,ATF2,RNF169,HTRA2,PRPF19,CDKN2AIP,BRD4,RFC3,POLR2L,POLR2G,BTG2,PPIE,TAOK1,POLR2D,NFATC2,DNAJA1,DCLRE1C,FANCE,POLG2,TRIM28,RAD54B,SUPT16H,RAD51C,NSMCE2,HIPK2,H2AFX,XRCC3,PPP5C,GEN1,MAPK1,XRCC4,EYA2,CSNK1D,ATMIN,RAD51D,POLQ,MIF,SLC30A9,MCM10,TRIP12,SHPRH,EYA1,BABAM1,MRPS26,SMC6,BLM,FOXO3,RMI1,MAD2L2,NEIL2,WRNIP1,RFWD3,CCNK,RPA2,HUWE1,CENPJ,PTPN11,GTSE1,COPS7B,CNOT6L,GTF2H2,MSH6,HMGN1,POLK,HELB,PRKDC,PARP4,TOP3A,MEN1,DDX39A,CHCHD6,POLR2A,MAPK3,RPA1,UPF1,POLE,NEIL3,TFDP1,PML,E2F1,AEN,HMGB2,WDR76,DDB1,IFI16 |
| 2.832e-24 | -54.22 | GO_ESTABLISHMENT_OF_PROTEIN_LOCALIZATION | MSigDB lists | GO_ESTABLISHMENT_OF_PROTEIN_LOCALIZATION | 1361 | 343 | 17377 | 2626 |
CCDC93,RAB14,TMED7,PDCD6IP,NUP188,TSC2,TAP1,AP3M2,SYNRG,RPL23A,CDK5,NAPG,SNUPN,RABGAP1L,RAB4A,AP1M1,DNM2,AP2B1,NUP153,SEH1L,SRP72,PGAP2,USO1,TMEM115,NRAS,ATG9A,AKT2,MCL1,NUTF2,MCFD2,ICMT,RAB22A,RAB2B,ARF4,PLEKHF2,SMAD2,TMED10,RPS27A,RPS14,EIF2D,ITGB1,ATP6V0C,BTF3,ARRB2,NMD3,LONP2,ZMAT3,AAAS,NXT2,SEC61G,GGA1,RHOC,RAB23,ACAP1,TMED3,PSEN1,VPS25,COPG2,COPB2,LMNA,NPLOC4,ATG4A,SNX18,FBXO7,ATP6V0A2,TNPO3,MVP,NUP85,SYTL3,TMED2,NAGPA,EIF5A,TIMM8B,GCC2,RPS10,SSR2,RPS24,MTX1,RIT1,TOMM40,PTTG1IP,GOSR1,RHOB,SEC31A,DERL1,SCARB2,KPNA1,NSF,SNX14,RHOG,EXOC3,ANKRD27,SYS1,RAB11B,RAF1,ANK3,RAC1,GPR89A,C5orf30,VTI1A,MYH9,TBC1D13,AP1B1,STAM,MOAP1,RAB21,AHCTF1,RALB,TBC1D22A,TBC1D14,NUP107,TNPO2,TAP2,GCC1,ATP6V1G1,SNX8,SEC61B,GOPC,WBP2,RPL38,ATP6V0A1,RAB1A,AP4E1,ERC1,SERP1,HSPA4,CHMP4A,PEX5,SEC61A1,RAB24,VPS26B,CORO1C,RPLP1,SEL1L,RHEBL1,RPS2,SCAMP3,TRAK1,FLOT1,BTN3A1,IFT27,RAB11A,WRB,JAKMIP1,RPL17,ARF5,RPL19,MTX2,IFT46,PACS2,PPP3CA,TNFAIP3,GUK1,DENND1B,DENND4C,RPL8,RABIF,PACS1,RAB3IP,RHOT1,ZP3,RPL27A,MACF1,YIF1A,HGS,KIF18A,RPL32,STX18,PML,SSNA1,ASNA1,YWHAH,GPR89B,VPS29,IPO4,SNAPIN,POLA2,COPA,MTX3,SNX15,UBE2Q1,SEC16A,RUFY1,BECN1,SSR1,RAB8A,RAP1A,NUP210,CDC42,TIMM23,ATG3,AP3S2,RAB35,PIK3R2,RP2,TIMM50,VPS13B,CDC37,PLK1,TLK1,EZR,STX16,RAB5B,LSG1,RHEB,OPTN,NECAP2,RPL37,TRAM2,EIF4ENIF1,TBC1D17,TIMM13,HSPB11,UEVLD,KPNA2,VPS4A,ROCK1,CLU,RPS26,ATP6V0E1,POT1,TBC1D12,RPS15,PHB2,GORASP1,CENPF,NACA,NKD2,RPL15,RAB6A,XPO7,RHBDD1,NUP205,RINL,KIF13B,ARL6IP1,GLE1,LRSAM1,ATP6V0D1,KDELR1,PREB,RPL6,KRAS,SYVN1,ZDHHC3,BBS12,RPL36,GNAS,GOLGA4,PCM1,SNAP23,EXOC4,SIL1,NUP62,YWHAZ,CTSA,RUVBL2,TOB1,CHMP2A,SNX27,TOMM20,CORO7,RPLP2,DYNLL1,COPE,ATP6V1B2,LYN,RPAIN,BCAP31,RPL11,ATP6V0B,MDM2,SAR1A,KIF14,AKAP8,BCAP29,SCAMP4,CLTB,LMAN1,AHCYL1,F2R,SNX25,RPL29,NXT1,RPL35,PPT1,RAB7A,NUP155,CHMP2B,RPS9,RPSA,RHBDF2,SURF4,TIMM17A,TOMM6,ARNTL,CEP55,AP1S1,CHMP4B,FAU,SMURF1,MAPK1,AP2S1,ABCA1,TSPAN5,PARD3,RAE1,NUP54,VPS45,ARF1,GGA2,AP3S1,TFRC,KLHL20,SEC24C,RRBP1,ARHGEF2,H2AFY,STAT3,MYO5A,CAMK2G,TGFB1,RHOA,NASP,SNX2,SCFD2,COG1,RHOT2,MAPK3,MFN2,RAB18,KPNA4,ATP6V1D,PDCD6,SEC23IP,GOLGA7,SNAP29,FAM126A,RBPJ,ATP6V1C1,CHMP7,HRAS,RAB3IL1 |
| 2.961e-24 | -54.18 | GO_MRNA_PROCESSING | MSigDB lists | GO_MRNA_PROCESSING | 402 | 142 | 17377 | 2626 |
DDX47,THOC1,PHRF1,RBM8A,ALKBH5,DHX8,USP39,SNRPD3,RBM4,SF3B2,PAPOLA,SNUPN,EIF4A3,NSRP1,METTL14,SRSF4,GPATCH1,TRA2B,CCAR1,PCBP2,SRPK2,SRSF10,CDC5L,SNRNP200,SNRPB,HNRNPF,DDX20,SREK1,LUC7L,DHX15,CLNS1A,IWS1,PAF1,GEMIN5,LUC7L3,PQBP1,PRPF4,RNASEL,SMNDC1,GEMIN7,PRPF38B,POLR2K,ZCCHC8,DHX9,CDK13,THRAP3,PDCD7,PRPF39,SRRT,METTL3,CDC73,PRPF18,RAVER2,SNRNP25,EFTUD2,BUD31,ZNF326,YBX1,GEMIN4,CPSF4,PABPC1,LUC7L2,SRSF11,POLR2I,SUGP2,SRSF5,SF3A2,RBM38,RBM25,SYNCRIP,POLR2J,RBMX,PRMT7,SNRNP70,TSEN15,SART1,SARNP,XAB2,SF3B1,PCBP1,PRKACA,APP,HNRNPA2B1,RBM23,ZNF473,GRSF1,TARDBP,AQR,CHTOP,AHCYL1,RBM15,ZC3H3,STRAP,CDK12,PRPF19,CSTF1,POLR2L,POLR2G,PPIE,CRNKL1,POLR2D,RNPS1,SLBP,PRPF3,BUD13,TXNL4A,SRSF1,SUGP1,LSM6,DHX16,HNRNPR,SNRPG,PDCD11,PRPF4B,CDC40,SRSF6,JMJD6,GTF2F1,RBM17,DNAJC8,CTNNBL1,CWC27,PPP1R8,GEMIN6,CNOT6L,GTF2H2,HNRNPM,RBM15B,YTHDC1,PSPC1,HELB,PPWD1,DDX39A,SYMPK,SNRPA,POLR2A,DDX23,HNRNPH3,KHSRP,ZRANB2,DDX5,SRSF3 |
| 2.973e-24 | -54.17 | GO_CHROMOSOME_ORGANIZATION | MSigDB lists | GO_CHROMOSOME_ORGANIZATION | 938 | 259 | 17377 | 2626 |
PDCD6IP,H2AFZ,KDM4A,CXXC1,CCNB1,MIS12,KIFC1,RAD23B,PDS5B,TAF5L,SMARCE1,DNMT1,SEH1L,USP34,ERCC1,EHMT1,AURKB,SMC2,USP22,MCM2,RFC2,GINS4,PRIM1,DOT1L,BRMS1,HHEX,BRD2,KIF18B,RPS27A,OGT,RRS1,HDAC2,RECQL,MAPRE1,MUM1,PRKAA1,DHX9,KIF23,TOP2B,PMF1,EZH1,SUPT7L,CDC73,SPAG5,SMC3,HDAC7,MCM5,MSH2,TNRC18,NUP85,TERF2,PRIM2,TSPYL4,MTA2,ZMYND11,ARID1A,KDM3A,XRCC5,SETD3,CABIN1,ZNF830,NDE1,CDK2,CDKN2A,ZNF207,ATXN3,DNMT3A,UBR2,SUZ12,CHD1L,PTTG1,NUF2,TERF2IP,AHCTF1,SP100,KDM2A,MTA1,NUP107,ATF2,SAP30,PSRC1,BRD4,RFC3,KAT7,TAOK1,CUL3,ELP4,NUSAP1,CDC23,GAR1,H2AFV,TRIM28,SUPT16H,KIF2A,RAD51C,CHMP4A,DSN1,SAFB,NSMCE2,H2AFX,BEND3,PPP5C,EYA2,MECP2,BABAM1,JMJD6,WDR5,BLM,RAB11A,HMG20A,RPA2,SUV39H2,HUWE1,PRDM4,AXIN2,NAA50,PRC1,COPS7B,NAP1L4,GTF2H2,NCOA2,MSH6,SMC4,NUDC,KAT2A,RPA1,CBX3,KIF18A,POLE,HMGB2,PURA,ESPL1,IPO4,DDB1,POLA2,UBN1,TAF6L,KIF2C,SIRT2,BECN1,TET3,PCNA,NOC2L,KIF22,MCMBP,CARM1,ARID4A,RYBP,COPS8,PLK1,RBX1,BAZ2A,TLK1,WDR82,UTP3,PBRM1,BRCA1,USP21,ASF1B,CHAF1A,PAF1,CHD3,BAZ1B,ACTB,VPS4A,COPS6,POT1,NAA60,HJURP,PHB2,CENPF,CTCF,RACGAP1,RLF,ARID1B,TTF1,RB1,MBD2,XPA,ZNF335,CTR9,KNTC1,HP1BP3,LDB1,RTF1,DAPK3,MBIP,NAP1L1,PALB2,CDCA5,PRMT7,RUVBL2,RBBP4,SMARCD1,MBD1,CHMP2A,ASH1L,ARID2,SMARCA4,CHD1,MEAF6,OIP5,SAP130,BRPF3,KIF14,AKAP8,TOP1MT,SAP30L,KDM3B,NUP155,DCLRE1C,KDM1B,CHMP2B,MBD3,RAD54B,RBL1,CEP55,ANP32E,CHMP4B,XRCC3,NCOA1,H3F3A,BRD9,RAD51D,CBX4,DNAJC2,RAE1,EYA1,SHPRH,CDCA8,SMC6,HMGN3,NCAPG,IRF4,PELO,H2AFY,SS18L1,PTGES3,CENPM,FBL,GINS1,NASP,HMGN5,PRKDC,HELB,TOP3A,RCOR1,RANGAP1,PRMT2,PCGF1,MEN1,UPF1,ATAD2,L3MBTL3,BIRC5,TAF12,CENPT,CHMP7,TERF1 |
| 3.105e-24 | -54.13 | GO_ORGANELLE_FISSION | MSigDB lists | GO_ORGANELLE_FISSION | 453 | 154 | 17377 | 2626 |
SKA3,PDCD6IP,XIAP,ENSA,KIF2C,SIRT2,CCNB1,UBE2I,BECN1,BIRC2,MIS12,KIFC1,NEK6,XRCC2,PDS5B,KIF22,NUP153,CDC25B,MCMBP,SEH1L,PLK1,PBK,NSUN2,MKI67,KIF15,CDC6,AURKB,SMC2,PBRM1,CCNF,ANLN,KIF18B,ZNF268,VPS4A,CHEK2,RRS1,MAPRE1,PPP1R12A,GORASP1,CENPF,KIF23,RACGAP1,TOP2B,HAUS4,PMF1,HAUS2,SPAG5,RB1,SMC3,SNX18,MSH2,TIMELESS,FBXL7,KNTC1,MYBL2,SEPT7,HAUS8,MASTL,CDC27,GOLGA2,CDCA5,FAM83D,VCPIP1,NUP62,NDE1,ZNF830,CDK2,CCNB2,ZNF207,CHMP2A,UBR2,PTTG1,ACTR3,TPX2,SMARCA4,NUF2,OIP5,CCNA2,KIF14,AKAP8,ANAPC7,CEP63,DCTN1,ANKLE2,PSRC1,MAPRE2,BIRC3,TUBGCP5,CUL3,NUSAP1,CDCA2,PKMYT1,CHMP2B,RAB1A,CDC23,TXNL4A,EML4,RAD54B,KIF2A,RAD51C,CHMP4A,CDC16,DSN1,NSMCE2,CEP55,XRCC3,CHMP4B,PPP5C,REEP4,PPP2R2D,RAD51D,ZC3HC1,KIF3B,CTDP1,KLHL21,BABAM1,DCTN2,CDCA3,CDCA8,CDK11B,NCAPG,CSNK1A1,RAB11A,TUBGCP2,MAD2L2,SAC3D1,FBXO5,CCNK,PTEN,PRC1,NAA50,ARHGEF2,MSH6,SMC4,NUDC,RHOA,ASPM,TOP3A,JTB,ANAPC2,KIF11,BORA,CDK11A,NEK1,KIF18A,BIRC5,ACOX1,CENPT,UBE2C,CHMP7,ESPL1,TERF1,SSSCA1,ANAPC4 |
| 3.122e-24 | -54.12 | central_nervous_system-medulla-primitive_neuroectodermal_tumour-medulloblastoma-classic | COSMIC cancer mutations | central_nervous_system-medulla-primitive_neuroectodermal_tumour-medulloblastoma-classic | 15206 | 2410 | 17385 | 2587 |
HECA,ZBTB10,ABCC10,HEXB,CCNL2,FBXO22,EEF2K,RAD23B,ATP13A3,DNM2,ZNRD1,FTSJ3,USP34,CCDC57,ERCC1,NRAS,EHMT1,KIF15,HNRNPF,WDHD1,MIER2,DIDO1,MCM2,RAB22A,SMAD2,MID1IP1,RPS27A,MPV17,COX5A,SMAD1,ZNF75A,ANXA11,SLC25A33,SEC61G,GGA1,MUM1,CCZ1,TRIO,CUTA,RAB23,KCTD17,HAUS4,EIF2AK4,APH1B,PARN,CDC73,MYL6B,ATG4A,TMEM179B,PDXP,SMC3,MVP,NSUN4,PPA1,IFRD1,AGGF1,FOXK1,RBM42,GTPBP4,MAP7D1,MRPL16,ELK1,EIF4H,RDH11,MAGED2,KPNA1,ETS2,TYW5,WIPI2,RUFY3,PDLIM5,ACSF2,EXOC3,RHOG,STARD7,C5orf30,VTI1A,SLC35B2,INO80E,LCLAT1,RCOR3,CPNE3,KIAA1147,RBM23,ZNF420,AHCTF1,TBC1D22A,TBC1D14,GMEB1,NSFL1C,SEPT11,GPD1L,ZC3H3,ARL5A,PDCL3,SNX8,ERMP1,EID1,IDH3A,POLR2D,HTATIP2,MEF2D,TMEM147,GSTCD,TANC1,MAT2A,VPS26B,NSMCE2,CORO1C,CAMKMT,PPP5C,PITRM1,TUBB,COMMD10,ZNF445,SRSF6,HABP4,CCM2,FLOT1,BTN3A1,ATG2B,ABHD14B,PPP1R3B,GOLM1,ZBTB45,HUWE1,ZNF260,NAA50,ANXA5,LTN1,UBE3B,NAP1L4,ZNF710,ST8SIA2,MED22,SPTAN1,STAU1,TCTEX1D2,DDX24,TACC1,MRS2,LDHA,HEBP2,LLPH,RAB3IP,TTC33,PICALM,SH3BP5,SLC19A1,ACOX1,FAM3C,AEN,PARP10,YWHAH,GPATCH4,FAM129A,TRIM11,YTHDC2,SNX15,RBM8A,ENSA,NENF,SND1,RUFY1,TRIM65,ZER1,PRNP,KRR1,RAB8A,NT5DC1,NOC2L,EIF5,TACC3,VPS13B,PTPN18,MIOS,SNRPB,MBLAC2,CDC6,UTP3,USP21,TRAM2,FBXO28,BCL7C,ARRDC1,ADAM9,DVL1,ZNF564,FUBP1,C1orf74,CTU2,PARP12,ZCCHC9,CENPF,LAMTOR3,CHCHD2,NCKAP1,LYRM2,RSAD1,TNS3,SUB1,RINL,SSBP3,MBD2,XPA,AHCY,RBM3,GLE1,LRSAM1,HDHD2,NTPCR,NSDHL,AMD1,CAMSAP1,ZNF761,METTL22,ICAM2,STYXL1,APPL1,BBS12,ANKRD46,RXRB,SDHB,PCM1,GALNT2,TMEM168,NLRC5,RUVBL2,BTBD10,MYO9A,CCNB2,USP7,GLT8D1,RPLP2,SUCLG1,ARID2,TMX4,SLC2A1,ATP6V1B2,PCBP1,LYN,BCAP31,VAV1,TMEM69,MRPL50,PSMA6,ZNF473,BRPF3,TARDBP,BCAP29,CTDSP2,PRPF19,PPIF,KDM3B,MND1,CLCN3,BIRC3,RAB7A,ANKRD33B,PPIE,CHMP2B,VDAC1,EIF3H,TMEM201,GLOD4,IDE,DHX16,UHRF2,XRCC3,CHMP4B,PARD3,BCL2L12,C19orf53,MCM10,KLHL21,PDAP1,CDCA8,TMX3,ARF1,SLC12A9,TUBGCP2,DNAJB9,HOMER1,POLR1B,RNF5,RBM15B,PPAN,RHOA,RPRD1A,BTAF1,TOP3A,ARHGEF12,PCGF1,DDX23,RAB18,CACNB1,PDCD6,ATP6V1D,L3MBTL3,FAM110A,NEIL3,CTBS,BBX,IMPDH1,TAF12,NR2F2,PGAM1,HIPK3,IFI16,TXN,H2AFZ,PNISR,TMEM203,PRKCSH,USP39,UBE2I,PARK7,SLC25A37,ASPHD2,ZNF428,RAB4A,TRA2B,SUCLG2,CISD2,TAF5L,SMARCE1,ZNF800,CDC5L,ZNF524,SGCE,NSUN2,USP22,CLNS1A,EIF3A,ZMYM3,DOT1L,IWS1,ANKRD10,WAS,KIF18B,TPP2,C1orf109,ZMAT3,B4GALT2,PRPF38B,RECQL,C9orf78,EWSR1,GADD45G,RRM1,ACAP1,B4GALT1,CYCS,FAM136A,SUPT7L,TMEM165,NPLOC4,CNOT3,WDR48,SPAG5,RTKN,CEP104,EXOSC7,KLHL5,LRRC8D,PPP4R1,MSH2,PIGG,FBXL7,MRPL40,SYTL3,FAM171A1,APOL1,EIF5A,GCC2,PRIM2,ELL2,RDH10,MFNG,RPS24,GORASP2,CAPZA2,ADRB2,CCT8,MTR,PHF6,PFDN5,SLCO4A1,TTC13,GOLGA2,RBMX,MED15,PIAS2,APPL2,SAMD8,NUDT3,CDKN2A,ZNF511,ATXN3,RAF1,KIAA0232,C2orf49,EPM2A,CD320,CCNA2,MTMR4,BRI3,TP53BP2,AQR,RBM12B,ILKAP,CDK12,SAP30,BRD4,DRAP1,NARF,LRRC8A,ELP4,ABHD11,PKMYT1,ASB13,SERP1,TRIM28,SUPT16H,EIF3K,CHMP4A,CBWD1,ATF6,XRCC4,ADAM23,PRPF4B,NDUFS1,DEPDC1,MECP2,SECISBP2,HMG20A,WWP2,SLC25A36,JAKMIP1,DNAJC8,AXIN2,CITED2,JMJD4,ANKRD37,KAT2A,TMEM126B,RABIF,ADSL,BMS1,KCNQ1,ARSK,MACF1,KIF11,KLF6,COMMD4,SMAP2,FADD,SH3GLB1,MYO1F,CBX3,TMEM127,INF2,PPP1R11,DUSP11,DDX5,WDR62,TAF6,ESPL1,PURA,DDB1,DEF6,IPO4,FAM83G,UBL3,NAT9,PIGM,LYRM4,GPR132,UBE2Q1,PTP4A3,BRIX1,MRPL19,ZNF696,SF3B2,PCYOX1L,CDC42,SYNM,GOT2,JAZF1,HADHB,RPF2,SLC35C2,CNNM3,CARM1,SRPK2,WDR41,LARS,ZCCHC10,CCDC138,LRBA,SUMF2,KMT2C,PRPSAP1,ASF1B,RPL37,MAN2A2,EIF4ENIF1,NIP7,U2SURP,MIA2,ZNF268,ATP6V0E1,PPP1R2,PM20D2,XPNPEP3,RGS2,LYAR,FAM89B,POLR2I,TRAFD1,SUGP2,GBA,SYVN1,DAPK3,ARHGAP15,MASTL,UAP1,NFIL3,FN3KRP,YWHAZ,CTSA,TMEM14A,TOB1,TSEN15,ADNP2,TCF12,PRKAB1,MDH2,SMARCA4,RRN3,UBXN2A,IARS,CD3EAP,KIF14,EXOSC1,CS,CLTB,DNAL4,CSTF1,POU2AF1,UBQLN4,HPDL,PGGT1B,SELPLG,SMU1,ATXN1,GLO1,OGDH,BICD2,CADM1,EDEM2,HERPUD2,TOLLIP,FANCE,MBD3,PDHX,RPS9,ALKBH6,SURF4,DUS3L,ARNTL,ANP32E,FKBP5,TMEM101,CCDC125,ABCA1,PDCD2L,GCLM,RAE1,DCTN2,CHIC2,PAWR,MXD4,DCUN1D4,PIP4K2A,XPR1,FERMT3,KIF5B,KLHL20,SEC24C,RRBP1,ARHGEF2,LDLRAD3,STAT3,MYO5A,NIPAL3,AMPD2,TXNL1,PHF20L1,DCAF6,FAM49B,TMEM39A,ATP2C1,RFFL,COG1,RCOR1,PRMT2,TFEB,LEMD2,UPF1,ELMO1,ZC3H7B,DTX4,ZMIZ1,TERF1,HRAS,CCDC93,FGFR1OP,TMED7,PIGQ,AGPAT1,CNTROB,PPP1R16B,MIS12,GSDMB,TTC9C,PDS5B,SENP1,PGAP2,TMEM115,PLEKHM3,DCUN1D5,PLEKHF2,BRMS1,PWWP2B,TRIM47,WDR11,AXIN1,SMG9,TRIM52,LONP2,NDUFV2,PHF23,CERK,SLC4A2,EZH1,ITGB5,LMNA,FBRS,MCTS1,DDX56,EIF2S2,SLC38A5,FOXN2,CARS2,PRRC2A,C16orf72,RB1CC1,ZMYND11,PGS1,MYBL2,UHRF1BP1,SRSF5,MPG,MATR3,CYB5A,NCDN,POLR2J,SETD3,PTAR1,CNOT6,NDE1,EGLN1,ZNF207,ANKRD27,ABCA3,SARNP,IVNS1ABP,MON1B,RMI2,TMEM97,NIT2,NUF2,ZNF267,TCF19,TMEM161B,KTN1,APP,PRKD3,CLUAP1,ATP2A2,UTP18,DUT,ANAPC7,RNF19A,FAM76B,CLN6,TMEM9,GCC1,RNF169,ADCY7,ATP6V1G1,ENPP4,RNPS1,CDCA2,FKBP3,GPR137,DDX17,CHCHD3,PEX5,CDC16,HIPK2,MBOAT1,TICAM1,PDXK,ZBTB11,TMBIM4,GMCL1,UBE4A,IL21R,ETS1,WRB,ZNF92,PNO1,CAPN2,ADD3,SUV39H2,TTLL12,TPCN1,TMX1,LYPLA2,HNRNPM,LDHB,PPP3CA,NUDT8,POLK,JTB,EMP3,MTMR12,ZP3,PDE3B,KIF18A,CCDC6,WNT5B,MAPK6,C4orf46,LY75,SLC25A19,RGL1,PSAP,WDR76,IGBP1,FAF1,SNAPIN,COX15,THOC1,AGRN,GNPDA1,GPBP1L1,PPP1R15B,CSNK2A1,EBNA1BP2,GIT2,BIRC2,ATPAF1,DLG5,ABL2,XRCC2,ZFYVE27,MCMBP,PTPRK,CDC37,METTL1,SP3,EXOSC6,HARS,GMFB,ESYT1,ANLN,RAB5B,RHEB,DPYSL3,TBC1D17,TIMM13,CDCA4,TONSL,NRM,NAGLU,ACTB,ZNF45,TMUB1,CTCF,ASAH1,DOCK11,CRLF3,ASXL2,LRRC14,SLC27A4,AFF1,MDFIC,MAML1,CYTH1,NQO2,UTP15,EIF2AK1,EIF4G2,ZDHHC3,MOSPD3,ITPRIPL1,CDC27,SNAP23,TBPL1,PRMT7,KCTD7,NDUFA5,CYLD,UGP2,DYNLL1,COPE,HCFC1R1,ZADH2,GGPS1,RPAIN,RAD23A,SEC11A,PDK2,ATP6V0B,TNFAIP8,STRBP,DUS4L,MRPL34,PDCD2,SAP30L,SLC39A9,CLPTM1,RPL29,RPL35,BTG2,DNAJC9,MTMR6,FRAT2,NFATC2,KDM1B,ARL5B,USP36,CCDC127,MRPL2,ATP1A1,CLK3,PSMD3,MAFK,CEP55,NDUFA11,DNAJC17,ZNF436,NCOA1,SLC25A39,ZC3HC1,ZNF146,ATXN7L2,CDC40,GOLIM4,SMAP1,RRP15,DAP,GNE,SMC6,ARFIP2,NKRF,CHAC2,BZW2,WRNIP1,SS18L1,CENPM,PTGES3,CAMK2G,MLEC,ZNF202,PPWD1,FAM50B,RHOT2,NEU1,TPD52L2,GOLGA7,TWSG1,GLG1,PGRMC1,FAM126A,SPCS3,RPS6KC1,UBE2C,PPCS,NDUFB6,TMEM41B,ZDHHC8,PLXNA1,CCNB1,SLC20A1,COMMD6,ABHD14A,POLR3K,C14orf119,ASAP2,SNUPN,CNPY4,TFG,PLCL2,SEH1L,ATG9A,PBK,MKI67,DDX20,AMDHD2,SLC17A5,GALNT7,CCNF,FOXRED1,RBM47,PTER,WDR4,DHTKD1,TRAF5,HDAC2,PWWP2A,HSPH1,LIME1,MAPRE1,CHTF18,ADO,KIF23,SLC35B1,NOTCH2,PMF1,JMY,FKBP1A,SLC31A1,SNX18,ATIC,ATP6V0A2,PIKFYVE,RNF135,LPCAT1,EEF1D,TMED2,FTL,PHF10,DDX28,ZNF84,SIGMAR1,PIP4K2C,RIT1,PLEC,KDM3A,SF3A2,FAS,EPRS,ZNF777,TMEM54,QARS,PPP3R1,TCOF1,CABLES1,NRBP1,DNMT3A,RWDD1,CKLF,TRIP10,SF3B1,SUZ12,CAST,RAC1,GPR89A,GNB2,FLAD1,APLP2,KDM2A,TNPO2,CDKN1B,TALDO1,GPX4,ATP13A1,RFC3,MAPRE2,ERF,CUL3,SLBP,KIAA1586,H2AFV,GAR1,PSMB9,POLG2,DHX57,NSA2,HSPA4,MRPL55,JAK1,TBL3,SEL1L,H2AFX,KLHDC4,B4GALT3,PDCD11,ATMIN,POLQ,POU3F2,NCOR2,ANKRD13D,PKP4,SCAMP3,CDCA3,SLC25A12,BLM,TMCC3,GTF2F1,CRAT,AHSA1,PRC1,UPF2,COPS7B,SLC38A10,CNPY3,UBE2M,IFT46,TMEM160,TSHZ1,ZFP64,DENND4C,DENND1B,WDR18,RPL8,ILF3,LRRC1,RHOT1,TSR2,MARK2,ECH1,PRDX1,PLD3,NUCB1,FBXO21,GNA12,C1orf131,PRDX3,PFDN4,HNRNPH3,STX18,TFDP1,KHSRP,ASNA1,CPEB2,SSSCA1,VPS29,BYSL,S100PBP,MIB2,IER2,PTMS,NOP2,UBN1,NF1,DCAF15,FLYWCH2,ALKBH5,MOGS,TAF6L,BECN1,MAPK14,SNAPC4,RNF103,BCAT2,MBD4,C18orf32,METTL14,IMPAD1,ZNHIT6,RCSD1,PHTF1,SRI,KIF22,ZBTB22,NFU1,TRIM14,ELOF1,COPS8,FYTTD1,TRIM8,RRM2,SOX4,ABHD5,UBTF,CXXC4,UEVLD,SPATA2,PQBP1,IARS2,ATXN2L,GALNT10,STARD3NL,RPS15,PIGN,AGTRAP,CIB1,XPO7,SRRT,ZNF449,CAPZA1,GLTP,BCL2,KIFAP3,N4BP2,HP1BP3,THNSL1,ISG15,CAND1,GNAS,TSC1,RBM25,CDCA5,ZFP90,NANP,RBBP4,ZBTB24,SMARCD1,MBD1,WASF2,MMACHC,TOMM20,IFI27L1,GNPNAT1,MPHOSPH8,HNRNPUL2,CHD1,MEAF6,C2orf68,CCDC50,AKAP8,PARL,RPN2,CHTOP,FAM3A,F2R,TMEM14C,SCYL3,ABI1,HTRA2,MOSPD1,RLIM,FAM172A,ZNF500,PSMB7,NLN,WIPF1,BUD13,NDUFB1,PEF1,EIF3G,BTBD1,TAB2,CHCHD1,TULP3,WDR59,CANT1,SCARB1,GAS2,USP11,SMURF1,TSPAN5,PPP2R2D,CDS2,MAGEH1,MRPL42,EYA1,CDK2AP2,MRPS26,LETMD1,KLF13,HDDC2,RGS1,MAN1A1,FBXO5,GART,PELO,TANK,BRD7,MRPL11,SAMD4B,ZDHHC18,GTF3C6,POLR3GL,WDR81,MEN1,ZNF407,MFN2,COX8A,ZRANB2,MBD6,SRSF3,ATP6V1C1,IDH3B,TATDN1,TSC2,LACTB2,CMTM6,RBM4,ZNF275,ANKRD39,RPL23A,CDKN2C,USF1,MECR,AP1M1,UPRT,CRY2,ECD,RNF26,TIPARP,LRRC59,ANKRD9,RHBDD2,MGAT5,BAK1,ZNF559,RHOBTB3,GABPA,WBP1,ARF4,GINS4,KRIT1,BOLA3,AHNAK,RAD18,PDRG1,RNASEL,CHPF2,PDCD4,SMNDC1,HIVEP3,KIAA0100,CLSPN,RHOC,DHX9,PDCD7,PSMD9,HAUS2,COPB2,TFAP4,CD59,RNFT1,MEGF8,RIMS3,FBXO7,EFTUD2,CPSF4,MRPL21,PHKG2,LUC7L2,SRSF11,EIF3L,MTA2,TYW1,ITM2A,SSR2,BCLAF1,MTX1,SFXN5,FNTA,PDLIM1,TXNDC16,ZNF830,TMEM159,MRPL3,ALS2,FAM72A,TRIM41,KARS,NQO1,POC1A,ANK3,PTTG1,TPX2,TBC1D13,DAZAP2,STMN1,GLRX3,REPS1,ABHD16A,FBXL6,SH3BP1,MTA1,UBA5,CLCN6,INTS12,C8orf59,RPRD1B,CGGBP1,CPNE1,SEC61B,POLR2L,FAM118B,GOPC,E2F3,CIRBP,RPL38,CRNKL1,PFKFB3,GORAB,RAB1A,GIGYF1,TMEM184C,PPP2CA,KIF2A,CCDC14,LSM6,RNF38,SNRPG,DMWD,USP13,MZT1,ZFP91,TRMT6,IP6K2,WDR5,SLC25A43,IFT27,PMVK,NEIL2,RRP36,SRXN1,RPA2,PSMD2,CLIC4,PDCD10,CBWD2,COQ4,ITGB8,ARF5,ARHGEF1,FBXL19,TTPAL,UTP20,GPS2,DBI,SSNA1,MRFAP1L1,CD81,TMEM131,WDR13,FANCI,CREM,FANCL,GLIS2,IL6ST,POP7,SLC44A1,MTPN,ASB6,PLK1,RPP25,SEPT9,CELSR2,RBX1,APH1A,RAD51AP1,CKAP2L,PSMG1,UBE2V1,EAF2,IL12RB1,KRTCAP2,LUC7L,LSG1,NECAP2,C1orf122,TRIM4,AGPAT2,CHD3,ZNF367,E2F4,PRPF4,BEND6,CLN3,DNAJC30,NGLY1,POT1,MYL12B,CCDC137,RMND5A,HJURP,PHB2,DNAJB2,FAM53C,NKD2,SDC2,KLC1,CDK13,ADCK5,COX4I1,DNAJB1,RAB6A,ARID1B,C1GALT1,MLX,UBE2Q2,CCP110,ZNF746,ARL6IP1,CTR9,NIPSNAP1,ABHD2,DCAF8,ACSL3,LDB1,MAP4K3,ARMC8,NMT2,IRF5,RPL36,HAUS8,MBIP,COX7A2L,ZDHHC7,SIL1,FAM122A,DTD1,UNC13C,BCCIP,SART1,TRAF7,NDUFAF2,TOR1AIP1,ZNF416,LAGE3,ZFYVE21,TM9SF3,RRAGC,ZNF121,NRF1,WDR44,PIN1,EFCAB11,RPAP1,CABLES2,LMAN1,AHCYL1,TOP1MT,STRAP,SPSB3,ZNF583,SNX25,ARHGAP17,POLR2G,ZNF780B,PPT1,DCLRE1C,MRPS14,RHBDF2,SUGP1,RBL1,FASTK,UBXN2B,STK38,AP1S1,SPRYD4,SLC22A23,H3F3A,CHID1,SMAD4,RAD51D,SLC30A9,CMAS,UNK,NADSYN1,HMGN3,NCAPG,SCYL2,FZD6,HERC3,GTPBP3,CTSS,RNLS,YTHDC1,ACP2,HMGN5,CSRP1,METTL5,ABCF2,TUFM,RANGAP1,PNPLA8,HAGH,API5,ZFR,SEC23IP,E2F1,TMEM219,USP20,RBPJ,PDCD6IP,MAX,GXYLT1,LUZP1,ADAM10,CXXC1,TSC22D3,AP3M2,CUL1,GYG1,NANS,MYEF2,ANKRD26,NOL11,FIZ1,ZNF200,MARCH2,SLC26A2,SRP72,KLF10,LACTB,RFC2,CBFB,RAB2B,MAP3K4,HHEX,LUC7L3,RPS14,MAP4,MRPL27,BTF3,PTPDC1,NMD3,CCDC59,PTOV1,COX5B,DNAJC5,SCOC,DHPS,POLR2K,ANKH,C16orf87,VAV2,GSPT2,TATDN3,DLGAP4,PXMP2,PRPF39,PSEN1,ZNF79,PDXDC1,VPS25,NDUFS7,YY1AP1,C12orf10,FAM192A,RPN1,LHX8,ARPC5,ZNRF2,TPST1,DAPK1,PIK3IP1,CYC1,SOCS5,FDFT1,PIGT,EMB,WDR1,ZNF574,C1orf35,EXOSC9,ARID1A,PTTG1IP,C9orf40,FXR1,GOSR1,TWISTNB,AKAP1,XRCC5,HMGN2,PI4K2A,CAT,DERL1,HSPBP1,MTHFD2,ARAP1,FAM83D,USP32,CABIN1,SMPD4,GPI,CYTIP,TP53RK,REPS2,RAB11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ELO2,ADAM17,HMGN1,NASP,ASPM,PRKAR1B,SYMPK,TARS,SNRPA,MAPK3,HSPA1B,HLA-B,ATAD2,PLAA,ZNF330,KBTBD7,PREPL |
| 3.122e-24 | -54.12 | central_nervous_system-medulla-primitive_neuroectodermal_tumour-medulloblastoma-desmoplastic | COSMIC cancer mutations | central_nervous_system-medulla-primitive_neuroectodermal_tumour-medulloblastoma-desmoplastic | 15206 | 2410 | 17385 | 2587 |
HECA,ZBTB10,ABCC10,HEXB,CCNL2,FBXO22,EEF2K,RAD23B,ATP13A3,DNM2,ZNRD1,FTSJ3,USP34,CCDC57,ERCC1,NRAS,EHMT1,KIF15,HNRNPF,WDHD1,MIER2,DIDO1,MCM2,RAB22A,SMAD2,MID1IP1,RPS27A,MPV17,COX5A,SMAD1,ZNF75A,ANXA11,SLC25A33,SEC61G,GGA1,MUM1,CCZ1,TRIO,CUTA,RAB23,KCTD17,HAUS4,EIF2AK4,APH1B,PARN,CDC73,MYL6B,ATG4A,TMEM179B,PDXP,SMC3,MVP,NSUN4,PPA1,IFRD1,AGGF1,FOXK1,RBM42,GTPBP4,MAP7D1,MRPL16,ELK1,EIF4H,RDH11,MAGED2,KPNA1,ETS2,TYW5,WIPI2,RUFY3,PDLIM5,ACSF2,RHOG,EXOC3,STARD7,C5orf30,VTI1A,SLC35B2,INO80E,LCLAT1,RCOR3,CPNE3,KIAA1147,RBM23,ZNF420,AHCTF1,TBC1D22A,TBC1D14,GMEB1,NSFL1C,SEPT11,GPD1L,ZC3H3,ARL5A,PDCL3,SNX8,ERMP1,EID1,IDH3A,POLR2D,HTATIP2,MEF2D,TMEM147,GSTCD,TANC1,MAT2A,VPS26B,NSMCE2,CORO1C,CAMKMT,PPP5C,PITRM1,TUBB,COMMD10,ZNF445,SRSF6,HABP4,CCM2,FLOT1,BTN3A1,ATG2B,ABHD14B,PPP1R3B,GOLM1,ZBTB45,HUWE1,ZNF260,NAA50,ANXA5,LTN1,UBE3B,NAP1L4,ZNF710,ST8SIA2,MED22,SPTAN1,STAU1,TCTEX1D2,DDX24,TACC1,MRS2,LDHA,HEBP2,LLPH,RAB3IP,TTC33,PICALM,SH3BP5,SLC19A1,ACOX1,FAM3C,AEN,PARP10,YWHAH,GPATCH4,FAM129A,TRIM11,YTHDC2,SNX15,RBM8A,ENSA,NENF,SND1,RUFY1,TRIM65,ZER1,PRNP,KRR1,RAB8A,NT5DC1,NOC2L,EIF5,TACC3,VPS13B,PTPN18,MIOS,SNRPB,MBLAC2,CDC6,UTP3,USP21,TRAM2,FBXO28,BCL7C,ARRDC1,ADAM9,DVL1,ZNF564,FUBP1,C1orf74,CTU2,PARP12,ZCCHC9,CENPF,LAMTOR3,CHCHD2,NCKAP1,LYRM2,RSAD1,TNS3,SUB1,RINL,SSBP3,MBD2,XPA,AHCY,RBM3,GLE1,LRSAM1,HDHD2,NTPCR,NSDHL,AMD1,CAMSAP1,ZNF761,METTL22,ICAM2,STYXL1,APPL1,BBS12,ANKRD46,RXRB,SDHB,PCM1,GALNT2,TMEM168,NLRC5,RUVBL2,MYO9A,BTBD10,CCNB2,USP7,GLT8D1,RPLP2,SUCLG1,ARID2,TMX4,SLC2A1,ATP6V1B2,PCBP1,LYN,BCAP31,VAV1,TMEM69,MRPL50,PSMA6,ZNF473,BRPF3,TARDBP,BCAP29,CTDSP2,PRPF19,PPIF,KDM3B,MND1,CLCN3,BIRC3,RAB7A,ANKRD33B,PPIE,CHMP2B,VDAC1,EIF3H,TMEM201,GLOD4,IDE,DHX16,UHRF2,CHMP4B,XRCC3,PARD3,BCL2L12,MCM10,C19orf53,KLHL21,PDAP1,CDCA8,TMX3,ARF1,SLC12A9,TUBGCP2,DNAJB9,HOMER1,POLR1B,RNF5,RBM15B,PPAN,RHOA,RPRD1A,BTAF1,TOP3A,ARHGEF12,PCGF1,DDX23,RAB18,CACNB1,PDCD6,ATP6V1D,L3MBTL3,FAM110A,NEIL3,CTBS,BBX,IMPDH1,TAF12,NR2F2,PGAM1,HIPK3,IFI16,TXN,H2AFZ,PNISR,TMEM203,PRKCSH,USP39,UBE2I,PARK7,SLC25A37,ASPHD2,ZNF428,RAB4A,TRA2B,SUCLG2,TAF5L,CISD2,SMARCE1,ZNF800,CDC5L,ZNF524,SGCE,NSUN2,USP22,CLNS1A,EIF3A,ZMYM3,DOT1L,IWS1,ANKRD10,WAS,KIF18B,TPP2,C1orf109,ZMAT3,B4GALT2,PRPF38B,RECQL,C9orf78,EWSR1,GADD45G,RRM1,ACAP1,B4GALT1,CYCS,FAM136A,SUPT7L,TMEM165,CNOT3,NPLOC4,SPAG5,WDR48,RTKN,CEP104,EXOSC7,KLHL5,LRRC8D,PPP4R1,MSH2,PIGG,FBXL7,MRPL40,SYTL3,FAM171A1,APOL1,EIF5A,GCC2,PRIM2,ELL2,RDH10,MFNG,RPS24,GORASP2,CAPZA2,ADRB2,CCT8,MTR,PHF6,PFDN5,SLCO4A1,TTC13,GOLGA2,RBMX,MED15,PIAS2,APPL2,SAMD8,NUDT3,CDKN2A,ZNF511,ATXN3,RAF1,KIAA0232,C2orf49,CD320,EPM2A,CCNA2,MTMR4,BRI3,TP53BP2,AQR,RBM12B,ILKAP,CDK12,SAP30,BRD4,DRAP1,NARF,LRRC8A,ELP4,ABHD11,PKMYT1,ASB13,SERP1,TRIM28,SUPT16H,EIF3K,CHMP4A,CBWD1,ATF6,XRCC4,PRPF4B,ADAM23,NDUFS1,DEPDC1,MECP2,SECISBP2,HMG20A,WWP2,JAKMIP1,SLC25A36,DNAJC8,AXIN2,CITED2,JMJD4,ANKRD37,KAT2A,TMEM126B,RABIF,ADSL,BMS1,KCNQ1,ARSK,MACF1,KIF11,COMMD4,KLF6,SMAP2,FADD,SH3GLB1,MYO1F,CBX3,TMEM127,INF2,PPP1R11,DUSP11,DDX5,WDR62,TAF6,ESPL1,PURA,DDB1,DEF6,IPO4,FAM83G,UBL3,PIGM,NAT9,LYRM4,GPR132,UBE2Q1,PTP4A3,BRIX1,MRPL19,ZNF696,SF3B2,PCYOX1L,CDC42,SYNM,GOT2,JAZF1,HADHB,RPF2,SLC35C2,CNNM3,CARM1,SRPK2,WDR41,LARS,ZCCHC10,CCDC138,LRBA,SUMF2,KMT2C,PRPSAP1,ASF1B,RPL37,MAN2A2,EIF4ENIF1,NIP7,U2SURP,MIA2,ZNF268,ATP6V0E1,PPP1R2,PM20D2,XPNPEP3,RGS2,LYAR,FAM89B,POLR2I,TRAFD1,SUGP2,GBA,SYVN1,DAPK3,ARHGAP15,MASTL,UAP1,NFIL3,FN3KRP,YWHAZ,CTSA,TMEM14A,TOB1,TSEN15,ADNP2,TCF12,PRKAB1,MDH2,SMARCA4,RRN3,UBXN2A,IARS,CD3EAP,KIF14,EXOSC1,CS,CLTB,DNAL4,CSTF1,POU2AF1,UBQLN4,HPDL,PGGT1B,SELPLG,SMU1,ATXN1,GLO1,OGDH,BICD2,CADM1,EDEM2,HERPUD2,TOLLIP,FANCE,MBD3,PDHX,RPS9,ALKBH6,SURF4,DUS3L,ARNTL,ANP32E,FKBP5,TMEM101,CCDC125,ABCA1,PDCD2L,GCLM,RAE1,DCTN2,CHIC2,PAWR,MXD4,DCUN1D4,PIP4K2A,XPR1,FERMT3,KIF5B,KLHL20,SEC24C,RRBP1,ARHGEF2,LDLRAD3,STAT3,MYO5A,NIPAL3,AMPD2,TXNL1,PHF20L1,DCAF6,FAM49B,TMEM39A,ATP2C1,RFFL,COG1,RCOR1,PRMT2,TFEB,LEMD2,UPF1,ELMO1,ZC3H7B,DTX4,ZMIZ1,TERF1,HRAS,CCDC93,FGFR1OP,TMED7,PIGQ,AGPAT1,CNTROB,PPP1R16B,MIS12,GSDMB,TTC9C,PDS5B,SENP1,PGAP2,TMEM115,PLEKHM3,DCUN1D5,PLEKHF2,BRMS1,PWWP2B,TRIM47,WDR11,AXIN1,SMG9,TRIM52,LONP2,NDUFV2,PHF23,CERK,SLC4A2,EZH1,ITGB5,LMNA,FBRS,MCTS1,DDX56,EIF2S2,SLC38A5,FOXN2,CARS2,PRRC2A,C16orf72,RB1CC1,ZMYND11,PGS1,MYBL2,UHRF1BP1,SRSF5,MPG,MATR3,CYB5A,NCDN,POLR2J,SETD3,PTAR1,CNOT6,NDE1,EGLN1,ZNF207,ANKRD27,ABCA3,SARNP,IVNS1ABP,MON1B,RMI2,TMEM97,NIT2,NUF2,ZNF267,TCF19,TMEM161B,KTN1,APP,PRKD3,CLUAP1,ATP2A2,UTP18,DUT,ANAPC7,RNF19A,FAM76B,CLN6,TMEM9,GCC1,RNF169,ADCY7,ATP6V1G1,ENPP4,RNPS1,CDCA2,FKBP3,GPR137,DDX17,CHCHD3,PEX5,CDC16,HIPK2,MBOAT1,TICAM1,PDXK,ZBTB11,TMBIM4,GMCL1,UBE4A,IL21R,ETS1,WRB,ZNF92,PNO1,CAPN2,ADD3,SUV39H2,TTLL12,TPCN1,TMX1,LYPLA2,HNRNPM,LDHB,PPP3CA,NUDT8,POLK,JTB,EMP3,MTMR12,ZP3,PDE3B,KIF18A,CCDC6,WNT5B,MAPK6,LY75,C4orf46,SLC25A19,RGL1,PSAP,WDR76,IGBP1,FAF1,SNAPIN,COX15,AGRN,THOC1,GNPDA1,GPBP1L1,PPP1R15B,CSNK2A1,EBNA1BP2,GIT2,BIRC2,ATPAF1,DLG5,ABL2,XRCC2,ZFYVE27,MCMBP,PTPRK,CDC37,METTL1,SP3,EXOSC6,HARS,GMFB,ESYT1,ANLN,RAB5B,RHEB,DPYSL3,TBC1D17,TIMM13,CDCA4,TONSL,NRM,NAGLU,ACTB,ZNF45,TMUB1,CTCF,ASAH1,DOCK11,CRLF3,ASXL2,LRRC14,SLC27A4,AFF1,MDFIC,MAML1,CYTH1,NQO2,UTP15,EIF2AK1,EIF4G2,ZDHHC3,MOSPD3,ITPRIPL1,CDC27,SNAP23,TBPL1,PRMT7,KCTD7,NDUFA5,CYLD,UGP2,DYNLL1,COPE,HCFC1R1,ZADH2,GGPS1,RPAIN,RAD23A,SEC11A,PDK2,ATP6V0B,STRBP,TNFAIP8,DUS4L,MRPL34,PDCD2,SAP30L,SLC39A9,CLPTM1,RPL29,RPL35,BTG2,DNAJC9,MTMR6,FRAT2,NFATC2,KDM1B,ARL5B,USP36,CCDC127,MRPL2,ATP1A1,CLK3,PSMD3,MAFK,CEP55,NDUFA11,DNAJC17,ZNF436,NCOA1,SLC25A39,ZC3HC1,ZNF146,ATXN7L2,CDC40,GOLIM4,SMAP1,RRP15,DAP,GNE,SMC6,ARFIP2,NKRF,CHAC2,BZW2,WRNIP1,SS18L1,CENPM,PTGES3,CAMK2G,MLEC,ZNF202,PPWD1,FAM50B,RHOT2,NEU1,TPD52L2,GOLGA7,TWSG1,PGRMC1,GLG1,FAM126A,SPCS3,RPS6KC1,UBE2C,PPCS,NDUFB6,TMEM41B,ZDHHC8,PLXNA1,CCNB1,SLC20A1,COMMD6,ABHD14A,POLR3K,C14orf119,ASAP2,SNUPN,CNPY4,TFG,PLCL2,SEH1L,ATG9A,PBK,MKI67,DDX20,AMDHD2,SLC17A5,GALNT7,CCNF,FOXRED1,RBM47,PTER,WDR4,DHTKD1,TRAF5,HDAC2,PWWP2A,HSPH1,LIME1,MAPRE1,CHTF18,ADO,KIF23,SLC35B1,NOTCH2,PMF1,JMY,FKBP1A,SLC31A1,SNX18,ATIC,ATP6V0A2,PIKFYVE,RNF135,LPCAT1,EEF1D,TMED2,FTL,PHF10,DDX28,ZNF84,SIGMAR1,PIP4K2C,RIT1,PLEC,KDM3A,SF3A2,FAS,EPRS,ZNF777,TMEM54,QARS,PPP3R1,TCOF1,CABLES1,NRBP1,DNMT3A,RWDD1,CKLF,TRIP10,SF3B1,SUZ12,CAST,RAC1,GPR89A,GNB2,FLAD1,APLP2,KDM2A,TNPO2,CDKN1B,TALDO1,GPX4,ATP13A1,RFC3,MAPRE2,ERF,CUL3,SLBP,KIAA1586,H2AFV,GAR1,PSMB9,POLG2,DHX57,NSA2,HSPA4,MRPL55,JAK1,TBL3,SEL1L,H2AFX,KLHDC4,B4GALT3,PDCD11,ATMIN,POLQ,POU3F2,NCOR2,ANKRD13D,PKP4,SCAMP3,CDCA3,SLC25A12,BLM,TMCC3,GTF2F1,CRAT,AHSA1,PRC1,UPF2,COPS7B,SLC38A10,CNPY3,UBE2M,IFT46,TMEM160,TSHZ1,ZFP64,DENND4C,DENND1B,WDR18,RPL8,ILF3,LRRC1,RHOT1,MARK2,TSR2,ECH1,PRDX1,PLD3,NUCB1,FBXO21,GNA12,C1orf131,PRDX3,PFDN4,HNRNPH3,STX18,TFDP1,KHSRP,ASNA1,CPEB2,SSSCA1,BYSL,VPS29,S100PBP,MIB2,IER2,PTMS,NOP2,UBN1,DCAF15,NF1,FLYWCH2,ALKBH5,MOGS,TAF6L,MAPK14,BECN1,SNAPC4,RNF103,BCAT2,MBD4,C18orf32,METTL14,ZNHIT6,IMPAD1,RCSD1,PHTF1,SRI,KIF22,ZBTB22,NFU1,TRIM14,ELOF1,COPS8,FYTTD1,TRIM8,RRM2,SOX4,ABHD5,UBTF,CXXC4,UEVLD,SPATA2,PQBP1,IARS2,ATXN2L,GALNT10,STARD3NL,RPS15,PIGN,AGTRAP,CIB1,XPO7,SRRT,ZNF449,CAPZA1,GLTP,KIFAP3,BCL2,N4BP2,HP1BP3,THNSL1,ISG15,CAND1,GNAS,TSC1,RBM25,CDCA5,ZFP90,NANP,RBBP4,ZBTB24,SMARCD1,MBD1,WASF2,MMACHC,TOMM20,IFI27L1,GNPNAT1,MPHOSPH8,HNRNPUL2,CHD1,MEAF6,C2orf68,CCDC50,AKAP8,PARL,RPN2,CHTOP,FAM3A,F2R,TMEM14C,SCYL3,ABI1,HTRA2,MOSPD1,RLIM,FAM172A,ZNF500,PSMB7,NLN,WIPF1,BUD13,NDUFB1,PEF1,EIF3G,BTBD1,TAB2,CHCHD1,TULP3,WDR59,CANT1,SCARB1,GAS2,USP11,SMURF1,PPP2R2D,TSPAN5,CDS2,MAGEH1,MRPL42,EYA1,CDK2AP2,MRPS26,LETMD1,KLF13,HDDC2,RGS1,MAN1A1,FBXO5,GART,PELO,TANK,BRD7,MRPL11,SAMD4B,ZDHHC18,GTF3C6,POLR3GL,WDR81,MEN1,ZNF407,MFN2,COX8A,ZRANB2,MBD6,SRSF3,ATP6V1C1,IDH3B,TATDN1,TSC2,LACTB2,CMTM6,RBM4,ZNF275,ANKRD39,RPL23A,CDKN2C,USF1,MECR,AP1M1,UPRT,CRY2,ECD,RNF26,TIPARP,LRRC59,ANKRD9,RHBDD2,MGAT5,BAK1,ZNF559,RHOBTB3,GABPA,WBP1,ARF4,GINS4,KRIT1,BOLA3,AHNAK,RAD18,PDRG1,RNASEL,CHPF2,SMNDC1,PDCD4,HIVEP3,KIAA0100,CLSPN,RHOC,DHX9,PDCD7,PSMD9,HAUS2,COPB2,TFAP4,CD59,RNFT1,RIMS3,MEGF8,EFTUD2,FBXO7,CPSF4,MRPL21,PHKG2,LUC7L2,SRSF11,EIF3L,MTA2,TYW1,ITM2A,SSR2,BCLAF1,MTX1,SFXN5,FNTA,PDLIM1,TXNDC16,ZNF830,TMEM159,MRPL3,ALS2,FAM72A,TRIM41,KARS,NQO1,POC1A,ANK3,PTTG1,TPX2,TBC1D13,DAZAP2,STMN1,GLRX3,REPS1,ABHD16A,FBXL6,SH3BP1,MTA1,UBA5,CLCN6,INTS12,C8orf59,RPRD1B,CGGBP1,CPNE1,SEC61B,POLR2L,FAM118B,GOPC,E2F3,CIRBP,RPL38,CRNKL1,PFKFB3,GORAB,RAB1A,GIGYF1,TMEM184C,PPP2CA,KIF2A,CCDC14,LSM6,RNF38,SNRPG,DMWD,USP13,MZT1,ZFP91,TRMT6,IP6K2,WDR5,SLC25A43,IFT27,PMVK,NEIL2,RRP36,SRXN1,RPA2,PSMD2,CLIC4,PDCD10,CBWD2,COQ4,ITGB8,ARF5,ARHGEF1,FBXL19,TTPAL,UTP20,GPS2,DBI,SSNA1,MRFAP1L1,CD81,TMEM131,WDR13,FANCI,CREM,FANCL,GLIS2,IL6ST,POP7,SLC44A1,MTPN,ASB6,PLK1,RPP25,SEPT9,CELSR2,RBX1,APH1A,RAD51AP1,CKAP2L,PSMG1,UBE2V1,EAF2,IL12RB1,KRTCAP2,LUC7L,LSG1,NECAP2,C1orf122,TRIM4,AGPAT2,CHD3,ZNF367,E2F4,PRPF4,BEND6,CLN3,DNAJC30,NGLY1,POT1,MYL12B,CCDC137,RMND5A,HJURP,PHB2,DNAJB2,FAM53C,NKD2,SDC2,KLC1,CDK13,ADCK5,COX4I1,DNAJB1,RAB6A,ARID1B,C1GALT1,MLX,UBE2Q2,CCP110,ZNF746,ARL6IP1,CTR9,NIPSNAP1,ABHD2,DCAF8,ACSL3,LDB1,MAP4K3,ARMC8,NMT2,IRF5,RPL36,HAUS8,MBIP,COX7A2L,ZDHHC7,SIL1,FAM122A,DTD1,UNC13C,BCCIP,SART1,TRAF7,NDUFAF2,TOR1AIP1,ZNF416,LAGE3,TM9SF3,ZFYVE21,RRAGC,ZNF121,NRF1,WDR44,PIN1,EFCAB11,RPAP1,CABLES2,LMAN1,AHCYL1,TOP1MT,STRAP,SPSB3,ZNF583,SNX25,ARHGAP17,POLR2G,ZNF780B,PPT1,DCLRE1C,MRPS14,RHBDF2,SUGP1,RBL1,FASTK,UBXN2B,STK38,AP1S1,SPRYD4,SLC22A23,H3F3A,CHID1,SMAD4,RAD51D,SLC30A9,UNK,CMAS,NADSYN1,HMGN3,NCAPG,SCYL2,FZD6,HERC3,GTPBP3,CTSS,RNLS,YTHDC1,ACP2,HMGN5,CSRP1,METTL5,ABCF2,TUFM,RANGAP1,PNPLA8,HAGH,API5,ZFR,SEC23IP,E2F1,TMEM219,USP20,RBPJ,PDCD6IP,MAX,LUZP1,GXYLT1,ADAM10,CXXC1,TSC22D3,AP3M2,CUL1,GYG1,NANS,MYEF2,ANKRD26,NOL11,FIZ1,ZNF200,MARCH2,SLC26A2,SRP72,KLF10,LACTB,RFC2,CBFB,RAB2B,MAP3K4,HHEX,LUC7L3,RPS14,MAP4,MRPL27,BTF3,PTPDC1,NMD3,CCDC59,PTOV1,COX5B,DNAJC5,SCOC,DHPS,POLR2K,ANKH,C16orf87,VAV2,GSPT2,TATDN3,DLGAP4,PXMP2,PRPF39,PSEN1,ZNF79,PDXDC1,VPS25,NDUFS7,YY1AP1,C12orf10,FAM192A,RPN1,LHX8,ARPC5,ZNRF2,TPST1,DAPK1,PIK3IP1,CYC1,SOCS5,FDFT1,PIGT,EMB,WDR1,ZNF574,C1orf35,EXOSC9,ARID1A,PTTG1IP,C9orf40,FXR1,GOSR1,TWISTNB,AKAP1,XRCC5,HMGN2,PI4K2A,CAT,DERL1,MTHFD2,HSPBP1,ARAP1,USP32,FAM83D,CABIN1,SMPD4,GPI,CYTIP,TP53RK,REPS2,RAB11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ELO2,ADAM17,HMGN1,NASP,ASPM,PRKAR1B,SYMPK,TARS,SNRPA,MAPK3,HSPA1B,HLA-B,ATAD2,PLAA,ZNF330,KBTBD7,PREPL |
| 3.122e-24 | -54.12 | central_nervous_system-medulla-primitive_neuroectodermal_tumour-medulloblastoma-large_cell | COSMIC cancer mutations | central_nervous_system-medulla-primitive_neuroectodermal_tumour-medulloblastoma-large_cell | 15206 | 2410 | 17385 | 2587 |
HECA,ZBTB10,ABCC10,HEXB,CCNL2,FBXO22,EEF2K,RAD23B,ATP13A3,DNM2,ZNRD1,FTSJ3,USP34,CCDC57,ERCC1,NRAS,EHMT1,KIF15,HNRNPF,WDHD1,MIER2,DIDO1,MCM2,RAB22A,SMAD2,MID1IP1,RPS27A,MPV17,COX5A,SMAD1,ZNF75A,ANXA11,SLC25A33,SEC61G,GGA1,MUM1,CCZ1,TRIO,CUTA,RAB23,KCTD17,HAUS4,EIF2AK4,APH1B,PARN,CDC73,MYL6B,ATG4A,TMEM179B,PDXP,SMC3,MVP,NSUN4,PPA1,IFRD1,AGGF1,FOXK1,RBM42,GTPBP4,MAP7D1,MRPL16,ELK1,EIF4H,RDH11,MAGED2,KPNA1,ETS2,TYW5,WIPI2,RUFY3,PDLIM5,ACSF2,EXOC3,RHOG,STARD7,VTI1A,C5orf30,INO80E,SLC35B2,LCLAT1,RCOR3,CPNE3,KIAA1147,RBM23,ZNF420,AHCTF1,TBC1D22A,TBC1D14,GMEB1,NSFL1C,SEPT11,GPD1L,ZC3H3,ARL5A,PDCL3,SNX8,ERMP1,EID1,IDH3A,POLR2D,HTATIP2,MEF2D,TMEM147,GSTCD,TANC1,MAT2A,VPS26B,NSMCE2,CORO1C,CAMKMT,PPP5C,PITRM1,TUBB,COMMD10,ZNF445,SRSF6,HABP4,CCM2,FLOT1,BTN3A1,ATG2B,ABHD14B,PPP1R3B,GOLM1,ZBTB45,HUWE1,ZNF260,NAA50,ANXA5,LTN1,UBE3B,NAP1L4,ZNF710,ST8SIA2,MED22,SPTAN1,STAU1,DDX24,TCTEX1D2,TACC1,MRS2,LDHA,HEBP2,LLPH,RAB3IP,TTC33,PICALM,SH3BP5,SLC19A1,ACOX1,FAM3C,AEN,PARP10,YWHAH,GPATCH4,FAM129A,TRIM11,YTHDC2,SNX15,RBM8A,ENSA,NENF,SND1,RUFY1,TRIM65,ZER1,PRNP,KRR1,RAB8A,NT5DC1,NOC2L,EIF5,TACC3,VPS13B,PTPN18,MIOS,SNRPB,MBLAC2,CDC6,UTP3,USP21,TRAM2,FBXO28,BCL7C,ARRDC1,ADAM9,DVL1,ZNF564,FUBP1,C1orf74,CTU2,PARP12,ZCCHC9,CENPF,LAMTOR3,CHCHD2,NCKAP1,LYRM2,RSAD1,TNS3,SUB1,RINL,SSBP3,MBD2,XPA,AHCY,RBM3,GLE1,LRSAM1,HDHD2,NTPCR,NSDHL,AMD1,CAMSAP1,ZNF761,METTL22,ICAM2,STYXL1,APPL1,BBS12,ANKRD46,RXRB,SDHB,PCM1,GALNT2,TMEM168,NLRC5,RUVBL2,BTBD10,MYO9A,CCNB2,USP7,GLT8D1,RPLP2,SUCLG1,ARID2,TMX4,SLC2A1,ATP6V1B2,PCBP1,LYN,BCAP31,VAV1,TMEM69,MRPL50,PSMA6,ZNF473,BRPF3,TARDBP,BCAP29,CTDSP2,PRPF19,PPIF,KDM3B,MND1,CLCN3,BIRC3,RAB7A,ANKRD33B,PPIE,CHMP2B,VDAC1,EIF3H,TMEM201,GLOD4,IDE,DHX16,UHRF2,CHMP4B,XRCC3,PARD3,BCL2L12,C19orf53,MCM10,KLHL21,PDAP1,TMX3,CDCA8,ARF1,SLC12A9,TUBGCP2,DNAJB9,HOMER1,POLR1B,RNF5,RBM15B,PPAN,RHOA,RPRD1A,BTAF1,TOP3A,ARHGEF12,PCGF1,DDX23,RAB18,CACNB1,PDCD6,ATP6V1D,L3MBTL3,FAM110A,NEIL3,CTBS,BBX,IMPDH1,TAF12,NR2F2,PGAM1,HIPK3,IFI16,TXN,H2AFZ,PNISR,TMEM203,PRKCSH,USP39,UBE2I,PARK7,SLC25A37,ASPHD2,ZNF428,RAB4A,TRA2B,SUCLG2,TAF5L,CISD2,SMARCE1,ZNF800,CDC5L,ZNF524,SGCE,NSUN2,USP22,CLNS1A,EIF3A,ZMYM3,DOT1L,IWS1,ANKRD10,WAS,KIF18B,TPP2,C1orf109,ZMAT3,B4GALT2,PRPF38B,RECQL,C9orf78,EWSR1,GADD45G,RRM1,ACAP1,B4GALT1,CYCS,FAM136A,SUPT7L,TMEM165,NPLOC4,CNOT3,SPAG5,WDR48,RTKN,CEP104,EXOSC7,KLHL5,LRRC8D,PPP4R1,MSH2,PIGG,FBXL7,MRPL40,SYTL3,FAM171A1,APOL1,EIF5A,GCC2,PRIM2,ELL2,RDH10,MFNG,RPS24,GORASP2,CAPZA2,ADRB2,CCT8,MTR,PHF6,PFDN5,SLCO4A1,TTC13,GOLGA2,RBMX,MED15,PIAS2,APPL2,SAMD8,NUDT3,CDKN2A,ZNF511,ATXN3,RAF1,KIAA0232,C2orf49,CD320,EPM2A,CCNA2,MTMR4,BRI3,TP53BP2,AQR,RBM12B,ILKAP,CDK12,SAP30,BRD4,DRAP1,NARF,LRRC8A,ELP4,ABHD11,PKMYT1,ASB13,SERP1,TRIM28,SUPT16H,EIF3K,CHMP4A,CBWD1,ATF6,XRCC4,PRPF4B,ADAM23,NDUFS1,DEPDC1,MECP2,SECISBP2,HMG20A,WWP2,JAKMIP1,SLC25A36,DNAJC8,AXIN2,CITED2,JMJD4,ANKRD37,KAT2A,TMEM126B,RABIF,ADSL,BMS1,KCNQ1,ARSK,MACF1,KIF11,COMMD4,KLF6,SMAP2,FADD,SH3GLB1,MYO1F,CBX3,TMEM127,INF2,PPP1R11,DUSP11,DDX5,WDR62,TAF6,ESPL1,PURA,DDB1,DEF6,IPO4,FAM83G,UBL3,NAT9,PIGM,LYRM4,GPR132,UBE2Q1,PTP4A3,BRIX1,MRPL19,ZNF696,SF3B2,PCYOX1L,CDC42,SYNM,GOT2,JAZF1,HADHB,RPF2,SLC35C2,CNNM3,CARM1,SRPK2,WDR41,LARS,ZCCHC10,CCDC138,LRBA,SUMF2,KMT2C,PRPSAP1,ASF1B,RPL37,MAN2A2,EIF4ENIF1,NIP7,U2SURP,MIA2,ZNF268,ATP6V0E1,PPP1R2,PM20D2,XPNPEP3,RGS2,LYAR,FAM89B,POLR2I,TRAFD1,SUGP2,GBA,SYVN1,DAPK3,ARHGAP15,MASTL,UAP1,NFIL3,FN3KRP,YWHAZ,CTSA,TMEM14A,TOB1,TSEN15,ADNP2,TCF12,PRKAB1,MDH2,SMARCA4,RRN3,UBXN2A,IARS,CD3EAP,KIF14,EXOSC1,CS,CLTB,DNAL4,CSTF1,POU2AF1,UBQLN4,HPDL,PGGT1B,SELPLG,SMU1,ATXN1,GLO1,OGDH,BICD2,CADM1,EDEM2,HERPUD2,TOLLIP,FANCE,MBD3,PDHX,RPS9,ALKBH6,SURF4,DUS3L,ARNTL,ANP32E,FKBP5,TMEM101,CCDC125,ABCA1,PDCD2L,GCLM,RAE1,DCTN2,CHIC2,PAWR,MXD4,DCUN1D4,PIP4K2A,XPR1,FERMT3,KIF5B,KLHL20,SEC24C,RRBP1,ARHGEF2,LDLRAD3,STAT3,MYO5A,NIPAL3,AMPD2,TXNL1,PHF20L1,DCAF6,FAM49B,TMEM39A,ATP2C1,RFFL,COG1,RCOR1,PRMT2,TFEB,LEMD2,UPF1,ELMO1,ZC3H7B,DTX4,ZMIZ1,TERF1,HRAS,CCDC93,FGFR1OP,TMED7,PIGQ,AGPAT1,CNTROB,PPP1R16B,MIS12,GSDMB,TTC9C,PDS5B,SENP1,PGAP2,TMEM115,PLEKHM3,DCUN1D5,PLEKHF2,BRMS1,PWWP2B,TRIM47,WDR11,AXIN1,SMG9,TRIM52,LONP2,NDUFV2,PHF23,CERK,SLC4A2,EZH1,ITGB5,LMNA,FBRS,MCTS1,DDX56,EIF2S2,SLC38A5,FOXN2,CARS2,PRRC2A,C16orf72,RB1CC1,ZMYND11,PGS1,MYBL2,UHRF1BP1,SRSF5,MPG,MATR3,CYB5A,NCDN,POLR2J,SETD3,PTAR1,CNOT6,NDE1,EGLN1,ZNF207,ANKRD27,ABCA3,SARNP,IVNS1ABP,MON1B,RMI2,TMEM97,NIT2,NUF2,ZNF267,TCF19,TMEM161B,KTN1,APP,PRKD3,CLUAP1,ATP2A2,UTP18,DUT,ANAPC7,RNF19A,FAM76B,CLN6,TMEM9,GCC1,RNF169,ADCY7,ATP6V1G1,ENPP4,RNPS1,CDCA2,FKBP3,GPR137,DDX17,CHCHD3,PEX5,CDC16,HIPK2,MBOAT1,TICAM1,PDXK,ZBTB11,TMBIM4,GMCL1,UBE4A,IL21R,ETS1,WRB,ZNF92,PNO1,CAPN2,ADD3,SUV39H2,TTLL12,TPCN1,TMX1,LYPLA2,HNRNPM,LDHB,PPP3CA,NUDT8,POLK,JTB,EMP3,MTMR12,ZP3,PDE3B,KIF18A,CCDC6,WNT5B,MAPK6,C4orf46,LY75,SLC25A19,RGL1,PSAP,WDR76,IGBP1,FAF1,SNAPIN,COX15,AGRN,THOC1,GNPDA1,GPBP1L1,PPP1R15B,CSNK2A1,EBNA1BP2,GIT2,BIRC2,ATPAF1,DLG5,ABL2,XRCC2,ZFYVE27,MCMBP,PTPRK,CDC37,SP3,METTL1,EXOSC6,HARS,GMFB,ESYT1,ANLN,RAB5B,RHEB,DPYSL3,TBC1D17,TIMM13,CDCA4,TONSL,NRM,NAGLU,ACTB,ZNF45,TMUB1,CTCF,ASAH1,DOCK11,CRLF3,ASXL2,LRRC14,SLC27A4,AFF1,MDFIC,MAML1,CYTH1,NQO2,UTP15,EIF2AK1,EIF4G2,ZDHHC3,MOSPD3,ITPRIPL1,CDC27,SNAP23,TBPL1,PRMT7,KCTD7,NDUFA5,CYLD,UGP2,DYNLL1,COPE,HCFC1R1,ZADH2,GGPS1,RPAIN,RAD23A,SEC11A,ATP6V0B,PDK2,STRBP,TNFAIP8,DUS4L,MRPL34,PDCD2,SAP30L,SLC39A9,CLPTM1,RPL29,RPL35,BTG2,DNAJC9,MTMR6,FRAT2,NFATC2,KDM1B,ARL5B,USP36,CCDC127,MRPL2,ATP1A1,CLK3,PSMD3,MAFK,CEP55,NDUFA11,DNAJC17,ZNF436,NCOA1,SLC25A39,ZC3HC1,ZNF146,ATXN7L2,CDC40,GOLIM4,SMAP1,RRP15,DAP,GNE,SMC6,ARFIP2,NKRF,CHAC2,BZW2,WRNIP1,SS18L1,CENPM,PTGES3,CAMK2G,MLEC,ZNF202,PPWD1,FAM50B,RHOT2,NEU1,TPD52L2,GOLGA7,TWSG1,PGRMC1,GLG1,FAM126A,SPCS3,RPS6KC1,UBE2C,PPCS,NDUFB6,TMEM41B,ZDHHC8,PLXNA1,CCNB1,SLC20A1,COMMD6,ABHD14A,POLR3K,C14orf119,ASAP2,SNUPN,CNPY4,PLCL2,TFG,SEH1L,ATG9A,PBK,MKI67,DDX20,AMDHD2,GALNT7,SLC17A5,CCNF,FOXRED1,RBM47,PTER,WDR4,DHTKD1,TRAF5,HDAC2,PWWP2A,HSPH1,LIME1,MAPRE1,CHTF18,ADO,KIF23,SLC35B1,NOTCH2,PMF1,JMY,FKBP1A,SLC31A1,SNX18,ATIC,ATP6V0A2,PIKFYVE,RNF135,LPCAT1,EEF1D,TMED2,FTL,PHF10,DDX28,ZNF84,SIGMAR1,PIP4K2C,RIT1,PLEC,KDM3A,SF3A2,FAS,EPRS,ZNF777,TMEM54,QARS,PPP3R1,TCOF1,CABLES1,NRBP1,DNMT3A,RWDD1,CKLF,TRIP10,SF3B1,CAST,SUZ12,RAC1,GPR89A,GNB2,FLAD1,APLP2,KDM2A,CDKN1B,TNPO2,TALDO1,GPX4,ATP13A1,RFC3,MAPRE2,ERF,CUL3,SLBP,KIAA1586,H2AFV,GAR1,PSMB9,POLG2,DHX57,NSA2,HSPA4,MRPL55,JAK1,TBL3,SEL1L,H2AFX,KLHDC4,B4GALT3,PDCD11,ATMIN,POLQ,POU3F2,NCOR2,ANKRD13D,PKP4,SCAMP3,CDCA3,SLC25A12,BLM,TMCC3,GTF2F1,CRAT,AHSA1,PRC1,UPF2,COPS7B,SLC38A10,CNPY3,UBE2M,IFT46,TMEM160,TSHZ1,ZFP64,DENND4C,DENND1B,WDR18,RPL8,ILF3,LRRC1,RHOT1,TSR2,MARK2,ECH1,PRDX1,PLD3,NUCB1,FBXO21,GNA12,C1orf131,PRDX3,PFDN4,HNRNPH3,STX18,TFDP1,KHSRP,ASNA1,CPEB2,SSSCA1,BYSL,VPS29,S100PBP,MIB2,IER2,PTMS,NOP2,UBN1,NF1,DCAF15,FLYWCH2,ALKBH5,MOGS,TAF6L,MAPK14,BECN1,SNAPC4,RNF103,BCAT2,MBD4,C18orf32,METTL14,ZNHIT6,IMPAD1,RCSD1,PHTF1,SRI,KIF22,ZBTB22,NFU1,TRIM14,ELOF1,COPS8,FYTTD1,TRIM8,RRM2,SOX4,ABHD5,CXXC4,UBTF,UEVLD,SPATA2,PQBP1,IARS2,ATXN2L,GALNT10,STARD3NL,RPS15,PIGN,AGTRAP,CIB1,XPO7,SRRT,ZNF449,CAPZA1,GLTP,KIFAP3,BCL2,N4BP2,HP1BP3,THNSL1,ISG15,CAND1,GNAS,TSC1,RBM25,CDCA5,ZFP90,NANP,RBBP4,ZBTB24,SMARCD1,MBD1,WASF2,MMACHC,TOMM20,IFI27L1,GNPNAT1,MPHOSPH8,HNRNPUL2,CHD1,MEAF6,C2orf68,CCDC50,AKAP8,PARL,RPN2,CHTOP,FAM3A,F2R,SCYL3,TMEM14C,ABI1,HTRA2,MOSPD1,RLIM,FAM172A,ZNF500,PSMB7,NLN,WIPF1,BUD13,NDUFB1,PEF1,EIF3G,BTBD1,TAB2,CHCHD1,TULP3,WDR59,CANT1,SCARB1,GAS2,USP11,SMURF1,PPP2R2D,TSPAN5,CDS2,MAGEH1,MRPL42,EYA1,CDK2AP2,MRPS26,LETMD1,KLF13,HDDC2,RGS1,MAN1A1,FBXO5,GART,PELO,TANK,BRD7,MRPL11,SAMD4B,ZDHHC18,GTF3C6,POLR3GL,WDR81,MEN1,ZNF407,MFN2,COX8A,ZRANB2,SRSF3,MBD6,ATP6V1C1,IDH3B,TATDN1,TSC2,LACTB2,CMTM6,RBM4,ZNF275,ANKRD39,RPL23A,CDKN2C,USF1,MECR,AP1M1,UPRT,CRY2,ECD,RNF26,TIPARP,LRRC59,ANKRD9,RHBDD2,MGAT5,BAK1,ZNF559,RHOBTB3,GABPA,WBP1,ARF4,GINS4,KRIT1,BOLA3,AHNAK,RAD18,PDRG1,RNASEL,CHPF2,SMNDC1,PDCD4,HIVEP3,KIAA0100,CLSPN,RHOC,DHX9,PDCD7,PSMD9,HAUS2,COPB2,CD59,TFAP4,RNFT1,MEGF8,RIMS3,EFTUD2,FBXO7,CPSF4,MRPL21,PHKG2,LUC7L2,SRSF11,EIF3L,MTA2,TYW1,ITM2A,SSR2,BCLAF1,MTX1,SFXN5,FNTA,PDLIM1,TXNDC16,ZNF830,TMEM159,MRPL3,ALS2,FAM72A,TRIM41,KARS,NQO1,POC1A,ANK3,PTTG1,TPX2,TBC1D13,DAZAP2,GLRX3,STMN1,REPS1,ABHD16A,FBXL6,SH3BP1,MTA1,UBA5,CLCN6,INTS12,C8orf59,RPRD1B,CGGBP1,CPNE1,SEC61B,POLR2L,FAM118B,GOPC,E2F3,CIRBP,RPL38,CRNKL1,PFKFB3,GORAB,RAB1A,GIGYF1,TMEM184C,PPP2CA,KIF2A,CCDC14,LSM6,RNF38,SNRPG,DMWD,USP13,MZT1,ZFP91,TRMT6,IP6K2,WDR5,SLC25A43,IFT27,PMVK,NEIL2,RRP36,SRXN1,RPA2,PSMD2,CLIC4,PDCD10,CBWD2,COQ4,ITGB8,ARF5,ARHGEF1,FBXL19,TTPAL,UTP20,GPS2,DBI,SSNA1,MRFAP1L1,CD81,TMEM131,WDR13,FANCI,CREM,FANCL,GLIS2,IL6ST,POP7,SLC44A1,MTPN,ASB6,PLK1,RPP25,CELSR2,SEPT9,RBX1,APH1A,RAD51AP1,CKAP2L,PSMG1,UBE2V1,EAF2,IL12RB1,KRTCAP2,LUC7L,LSG1,NECAP2,C1orf122,TRIM4,AGPAT2,CHD3,ZNF367,E2F4,PRPF4,BEND6,CLN3,DNAJC30,NGLY1,POT1,MYL12B,CCDC137,RMND5A,HJURP,PHB2,DNAJB2,FAM53C,NKD2,SDC2,KLC1,CDK13,ADCK5,COX4I1,DNAJB1,RAB6A,ARID1B,C1GALT1,MLX,UBE2Q2,CCP110,ZNF746,ARL6IP1,CTR9,NIPSNAP1,ABHD2,DCAF8,ACSL3,LDB1,MAP4K3,ARMC8,NMT2,IRF5,RPL36,HAUS8,MBIP,COX7A2L,ZDHHC7,SIL1,FAM122A,DTD1,UNC13C,BCCIP,SART1,TRAF7,NDUFAF2,TOR1AIP1,ZNF416,LAGE3,ZFYVE21,TM9SF3,RRAGC,ZNF121,NRF1,WDR44,PIN1,EFCAB11,RPAP1,CABLES2,LMAN1,AHCYL1,TOP1MT,STRAP,SPSB3,ZNF583,SNX25,ARHGAP17,POLR2G,ZNF780B,PPT1,DCLRE1C,MRPS14,RHBDF2,SUGP1,RBL1,FASTK,UBXN2B,STK38,AP1S1,SPRYD4,SLC22A23,H3F3A,CHID1,SMAD4,RAD51D,SLC30A9,CMAS,UNK,NADSYN1,HMGN3,NCAPG,SCYL2,FZD6,HERC3,GTPBP3,CTSS,RNLS,YTHDC1,ACP2,HMGN5,CSRP1,METTL5,ABCF2,TUFM,RANGAP1,PNPLA8,HAGH,API5,ZFR,SEC23IP,E2F1,TMEM219,USP20,RBPJ,PDCD6IP,MAX,LUZP1,GXYLT1,ADAM10,CXXC1,TSC22D3,AP3M2,CUL1,GYG1,NANS,MYEF2,ANKRD26,NOL11,FIZ1,ZNF200,MARCH2,SLC26A2,SRP72,KLF10,LACTB,RFC2,CBFB,RAB2B,MAP3K4,HHEX,LUC7L3,RPS14,MAP4,MRPL27,BTF3,PTPDC1,NMD3,CCDC59,PTOV1,COX5B,DNAJC5,SCOC,DHPS,POLR2K,ANKH,C16orf87,VAV2,GSPT2,TATDN3,DLGAP4,PXMP2,PRPF39,PSEN1,ZNF79,PDXDC1,VPS25,NDUFS7,YY1AP1,C12orf10,FAM192A,RPN1,LHX8,ARPC5,ZNRF2,TPST1,DAPK1,PIK3IP1,CYC1,SOCS5,FDFT1,PIGT,EMB,WDR1,ZNF574,C1orf35,EXOSC9,ARID1A,PTTG1IP,C9orf40,FXR1,GOSR1,TWISTNB,AKAP1,XRCC5,HMGN2,PI4K2A,CAT,DERL1,HSPBP1,MTHFD2,ARAP1,USP32,FAM83D,CABIN1,SMPD4,GPI,CYTIP,TP53RK,REPS2,RAB11B,UROD,SLC39A13,POMP,BCL2L1,NUDT19,DECR1,RALB,SIAH1,ADCY9,LPIN2,MRPS27,SOCS6,TTC3,RNASEH2A,CFL1,ANKLE2,CDC123,VDAC2,EDF1,EML4,ERC1,AMZ2,ANKZF1,ZNF282,DSN1,DDOST,HINT1,DGCR8,SAFB,HAGHL,RWDD4,FTSJ1,LMBR1,NCLN,BEND3,EYA2,DYNC1LI2,MANBA,B4GALT5,SLC41A1,FAM76A,TKT,CBLL1,ARGLU1,LANCL1,POFUT1,FAM8A1,HEATR5B,HLA-A,EBP,RFWD3,NDUFA2,FUT8,BTF3L4,PTPN11,MRPL54,FEM1B,RPL19,CNN2,NDUFA3,MTX2,MSH6,PDLIM2,LONRF3,RFXANK,FBXO9,GUF1,RPL32,ZHX1,NDUFS5,WDR91,GPR89B,HIGD2A,ZBED3,RORB,POLA2,ZNF76,COPA,UQCR10,HMGXB3,ABCB10,COMMD5,MAP1LC3B,DST,RAB35,SIVA1,GPATCH1,DRAM2,DEAF1,SNRNP200,LAP3,NCK1,VHL,SREK1,ARHGDIB,PITPNB,HSPB11,BRWD1,PPM1G,SH3GLB2,CRCP,BAZ1B,CAB39,ACBD4,STK11,CLU,CHEK2,ZSWIM3,TSTD2,MRPL13,CHPT1,DCAF5,CAPN1,UBE2D3,NSMCE4A,PPP1R12A,ZCCHC8,GORASP1,UBXN1,NACA,RPL15,PCSK7,THRAP3,QSOX2,TTF1,PRPF18,CHKA,DTL,MED10,ZRANB1,MCPH1,SLC12A2,ATP6V0D1,CSNK1G3,CREG1,NUDT4,RPL6,VKORC1,SLTM,EVC2,KLHL15,SIAH2,SLC16A1,EHD4,SNRNP70,C11orf1,APOL2,N4BP2L2,SNX27,CHMP2A,CORO7,FEZ2,UCK2,PMS2,UCK1,CLCC1,EXT2,MXD1,USP5,HNRNPA2B1,SAP130,NVL,PPP6C,CYB5R1,ZNF770,EBAG9,RNF25,PCGF6,METTL2A,FAM72B,PON2,HNRNPR,STAT6,HPS5,MAPK1,BRD9,TMEM33,NAT14,DNAJC2,TRIP12,SHPRH,SCYL1,VPS45,GFM2,SPPL2A,FASTKD3,FGFR3,MZT2A,PPIG,ZDHHC13,TMEM99,H2AFY,NDUFS8,ATG13,ERI3,FBL,SLC35A1,FRMD8,MICAL3,TGFB1,B3GALT6,ELOVL5,HEMK1,TIMMDC1,HELB,PSPC1,MIER1,SCFD2,NDRG3,MTMR3,ACAT1,CENPT,PLOD3,RAB3IL1,RAB14,ADD1,KDM4A,MRPS15,XIAP,DHX8,GLUD1,ANKRD23,CDK5,CALM2,PSMD1,NEK6,NSRP1,RABGAP1L,SRSF4,FNIP2,KCNAB2,PCBP2,PLK3,ZNF672,HSDL1,MRPL43,TOPORS,MCL1,PPFIA3,SMC2,ICMT,SLC50A1,STOML2,LIMK1,ZNF689,PRDX5,ATE1,MLYCD,ST3GAL2,ATP6V0C,FBXL3,TFDP2,E2F2,PFKP,AAAS,DDX42,SSRP1,MRPL9,MRPS2,STRN4,TOP2B,ZNRF3,TMED3,DDRGK1,RAVER2,GNS,INTS7,INPP5A,MCM5,PHF14,ZNF326,NAGPA,TIMM8B,ETV3,TSPAN31,DHX29,TEX10,MAN1B1,RPS10,CBFA2T2,ABCF1,RHOB,LRRC14B,DTWD1,PTPRF,SCARB2,CCDC86,DUSP3,SLAIN1,MDH1,HEXA,RNF139,SNX14,ZNF296,TRERF1,UBR2,CHD1L,ACTR3,WDTC1,MYH9,CREBL2,NIPA2,PRKACA,SAFB2,STAM,ARL6IP6,RAB21,SP100,ZKSCAN1,DDA1,ANKRD13C,MAVS,CEP63,TMEM136,ATF2,RBM15,DCTN1,SHOC2,PSRC1,MAP4K4,WBP2,ATP6V0A1,NDUFA7,DNAJA1,TAZ,TAF2,SEC61A1,RPLP1,WDR7,CBLN2,RBMS1,FUS,GEN1,LRP8,COIL,LRCH1,GALK1,RPS2,SESTD1,TRAK1,JMJD6,SIKE1,AKT1S1,KRI1,FBXO3,ERH,GATC,PPP1R8,PRDM4,GTSE1,GEMIN6,DCP1A,SGCB,S100A6,IMPA2,NUDC,PDPK1,TK1,GUK1,TNFAIP3,GALC,ZNF512,KIAA0930,MRPS10,DDX39A,RPA1,ZNF180,ZNF862,KEAP1,POLE,TATDN2,PITX1,CAPN7,LRPPRC,PML,HMGB2,USF2,ANAPC4,SRM,DDX47,MCCC1,CDC42SE2,S1PR2,CDIPT,KCMF1,SSR1,LIN9,PCNA,ZNF639,TRMU,ETV6,PIK3R2,PPCDC,TXLNA,FAM86C1,MYBL1,MRPL32,CCAR1,ABCC5,PBXIP1,TLK1,MRPL12,EZR,LNX2,LRP5,BRCA1,PRKRA,STX16,EPB41,SEPT1,SOCS4,QRSL1,GLCCI1,NUDT11,GEMIN7,LZTR1,RACGAP1,PPP3CB,B4GALT4,RLF,RAPGEF6,SNRNP25,RB1,VASP,MED8,VMP1,PPIL2,MEA1,TIMELESS,AHDC1,ALDH18A1,TMEM8A,ABCC1,PREB,TRAPPC9,AACS,MEMO1,KRAS,RTF1,UBE4B,NFATC2IP,LY6E,ARPC1A,ZNF174,PSMC4,GOLGA4,SYNCRIP,PRPS2,NIPA1,TIGD2,RNF114,FOXM1,MRPL39,XAB2,DUSP22,COMMD8,RPL11,CSDE1,MDM2,CORO1A,METTL9,MINPP1,POC5,DVL2,GM2A,PSMA8,COQ10B,CPOX,TIGD5,SLC26A6,CYP20A1,PRPF3,TXNL4A,RPSA,SRSF1,DNAJC10,SCAP,ZNF700,PLEKHG4B,TIMM17A,FAU,LTA4H,AP2S1,USP53,CTDP1,MIF4GD,CDT1,ARID5A,SUMF1,GGA2,AP3S1,CSNK1A1,RMI1,TFRC,PTPN2,IRF4,STARD9,GSTK1,NDUFV1,SLC1A4,CWC27,SLC35B4,DDX31,ABCD1,RPAP3,CNTN5,SNX2,ZMYM5,CCDC34,CHCHD6,BSDC1,KPNA4,CDKN2AIPNL,FBXO41,BIRC5,TFE3,SNAP29,CDCA7L,PKD2,ACADM,CHMP7,SAT2,GCSH,ZNF496,TMEM109,TAP1,NHLRC3,IKBIP,EIF1B,ELMOD2,KIFC1,DBNDD1,RNASEK,CDC25B,PRADC1,DNMT1,NOL12,USO1,AKT2,NOL8,GNG7,AURKB,MCFD2,SLC25A5,ZFAND5,MAK16,STT3A,TMED10,PSMD8,EIF2D,ITGB1,PTPN7,UQCRH,RRS1,ARRB2,RTN3,SVIP,DDX58,WSB2,PPIB,MUT,GMFG,HLA-E,NDUFA4,MAN2B1,METTL3,CFLAR,NDUFS4,RNF121,MEX3C,KLF16,HDAC7,DAD1,BDH1,PCYT2,GNAI2,ANKHD1,TERF2,MORC3,KCTD20,SEPT8,DCTD,TOMM40,ADSS,SERTAD2,SERF2,ZFP92,NSF,DCK,ERGIC3,ACLY,LPCAT4,VCPIP1,YY1,PPP6R2,MAP3K5,PPP6R3,RNF14,CDK2,ZC3HAV1,SYS1,ZBTB37,URB2,EIF3D,MAGED1,KLHL18,ADPGK,SLC25A44,AP1B1,SDHA,PHC2,CRKL,MOAP1,TERF2IP,CYHR1,ZNF75D,SHC1,UCHL5,NAA35,TMBIM1,CCT2,CDKN2AIP,MKLN1,GALK2,CDC23,SHCBP1,AP4E1,PRDM11,VEZF1,PPP2R5A,ACYP1,STAT1,PPA2,TRIM32,RHEBL1,C1orf112,MRI1,TCF3,BRAP,AGPAT3,MYNN,SDF2L1,SPR,RAB11A,REEP5,FOXO3,MAD2L2,CCDC28A,PIP5K1C,RBM17,MAT2B,PTEN,CENPJ,TAGLN2,CREB1,SMC4,RNASEH2C,NEK7,NET1,PARP4,TBRG4,ANAPC2,RPL27A,YIF1A,SGSH,HGS,TTLL4,SLC38A7,MFAP1,CCDC69,BRWD3,ESYT2,SKA3,NPHP4,UBE2E2,HNRNPAB,PLXNC1,TMEM184B,ST13,DNAJC24,ZNF107,KIF2C,SLC29A1,AGFG1,SIRT2,FKBP2,USP48,SNRPD3,UBQLN2,CUTC,EDC3,UBLCP1,ZNF804A,RAP1A,THADA,EIF4A3,AP3S2,ATG3,DPYSL2,PPP1R12C,AKR1B1,NDUFB9,JOSD1,RP2,TTC4,TECR,ARID4A,FGFR1OP2,TIMM50,TDP1,DPM1,FOPNL,SLC16A7,WDR82,SLC25A22,STK17B,DHX15,CHAF1A,GEMIN5,COPS6,SASS6,RPS26,PSMC1,SLC12A7,TBC1D12,TM9SF4,ZNF768,UFC1,MED13L,TIA1,MEF2A,EPHX2,PITHD1,RHBDD1,NFATC3,BANF1,BUD31,ZNF335,YBX1,KNTC1,ACAD8,UBE3C,ZNF189,ALDH9A1,KDELR1,TSTA3,CIC,PSMA1,NAP1L1,EXOC4,KIAA1328,PITPNA,NAA20,PTDSS1,MZT2B,PDSS2,C7orf26,TMEM106C,IMMT,ASH1L,CHERP,WDYHV1,PLAGL2,CHKB,IRF3,TWF2,ANKRD28,FARSA,SAR1A,APOOL,PDIA6,ACSL5,TOR1AIP2,AZI2,GFER,RAD54B,TMEM41A,DAP3,ZNF317,GADD45B,AKNA,REEP4,CBX4,MIF,KIF3B,GOLPH3L,SH2D3A,CASP6,TOR3A,SRGN,DBF4,MFSD10,SAC3D1,CTNNBL1,YIF1B,CLDND1,TTC17,SLC25A1,GINS1,CSNK1G2,TELO2,ADAM17,HMGN1,NASP,ASPM,PRKAR1B,SYMPK,TARS,SNRPA,MAPK3,HSPA1B,HLA-B,ATAD2,PLAA,ZNF330,KBTBD7,PREPL |
| 3.122e-24 | -54.12 | central_nervous_system-medulla-primitive_neuroectodermal_tumour-medulloblastoma | COSMIC cancer mutations | central_nervous_system-medulla-primitive_neuroectodermal_tumour-medulloblastoma | 15206 | 2410 | 17385 | 2587 |
HECA,ZBTB10,ABCC10,HEXB,CCNL2,FBXO22,EEF2K,RAD23B,ATP13A3,DNM2,ZNRD1,FTSJ3,USP34,CCDC57,ERCC1,NRAS,EHMT1,KIF15,HNRNPF,WDHD1,MIER2,DIDO1,MCM2,RAB22A,SMAD2,MID1IP1,RPS27A,MPV17,COX5A,SMAD1,ZNF75A,ANXA11,SLC25A33,SEC61G,GGA1,MUM1,CCZ1,TRIO,CUTA,RAB23,KCTD17,HAUS4,EIF2AK4,APH1B,PARN,CDC73,MYL6B,ATG4A,TMEM179B,PDXP,SMC3,MVP,NSUN4,PPA1,IFRD1,AGGF1,FOXK1,RBM42,GTPBP4,MAP7D1,MRPL16,ELK1,EIF4H,RDH11,MAGED2,KPNA1,ETS2,TYW5,WIPI2,RUFY3,PDLIM5,ACSF2,EXOC3,RHOG,STARD7,C5orf30,VTI1A,INO80E,SLC35B2,RCOR3,LCLAT1,CPNE3,KIAA1147,RBM23,ZNF420,AHCTF1,TBC1D22A,TBC1D14,GMEB1,NSFL1C,SEPT11,GPD1L,ZC3H3,ARL5A,PDCL3,SNX8,ERMP1,EID1,IDH3A,POLR2D,HTATIP2,MEF2D,TMEM147,GSTCD,TANC1,MAT2A,VPS26B,NSMCE2,CORO1C,CAMKMT,PPP5C,PITRM1,TUBB,COMMD10,ZNF445,SRSF6,HABP4,CCM2,FLOT1,BTN3A1,ATG2B,ABHD14B,PPP1R3B,GOLM1,ZBTB45,HUWE1,ZNF260,NAA50,ANXA5,LTN1,UBE3B,NAP1L4,ZNF710,ST8SIA2,MED22,SPTAN1,STAU1,DDX24,TCTEX1D2,TACC1,MRS2,LDHA,HEBP2,LLPH,RAB3IP,TTC33,PICALM,SH3BP5,SLC19A1,ACOX1,FAM3C,AEN,PARP10,YWHAH,GPATCH4,FAM129A,TRIM11,YTHDC2,SNX15,RBM8A,ENSA,NENF,SND1,RUFY1,TRIM65,ZER1,PRNP,KRR1,RAB8A,NT5DC1,NOC2L,EIF5,TACC3,VPS13B,PTPN18,MIOS,MBLAC2,SNRPB,CDC6,UTP3,USP21,TRAM2,FBXO28,BCL7C,ARRDC1,ADAM9,DVL1,ZNF564,FUBP1,C1orf74,CTU2,PARP12,ZCCHC9,CENPF,LAMTOR3,CHCHD2,NCKAP1,LYRM2,RSAD1,TNS3,SUB1,RINL,SSBP3,MBD2,XPA,AHCY,RBM3,GLE1,LRSAM1,HDHD2,NTPCR,NSDHL,AMD1,CAMSAP1,ZNF761,METTL22,ICAM2,STYXL1,APPL1,BBS12,ANKRD46,RXRB,SDHB,PCM1,GALNT2,TMEM168,NLRC5,RUVBL2,BTBD10,MYO9A,CCNB2,USP7,GLT8D1,RPLP2,SUCLG1,ARID2,TMX4,SLC2A1,ATP6V1B2,PCBP1,LYN,BCAP31,VAV1,MRPL50,TMEM69,PSMA6,ZNF473,BRPF3,TARDBP,BCAP29,CTDSP2,PRPF19,PPIF,KDM3B,MND1,CLCN3,BIRC3,RAB7A,ANKRD33B,PPIE,CHMP2B,VDAC1,EIF3H,TMEM201,GLOD4,IDE,DHX16,UHRF2,CHMP4B,XRCC3,PARD3,BCL2L12,C19orf53,MCM10,KLHL21,PDAP1,TMX3,CDCA8,ARF1,SLC12A9,TUBGCP2,DNAJB9,HOMER1,POLR1B,RNF5,RBM15B,PPAN,RHOA,RPRD1A,BTAF1,TOP3A,ARHGEF12,PCGF1,DDX23,RAB18,CACNB1,PDCD6,ATP6V1D,L3MBTL3,FAM110A,NEIL3,CTBS,BBX,IMPDH1,TAF12,NR2F2,PGAM1,HIPK3,IFI16,TXN,H2AFZ,PNISR,TMEM203,PRKCSH,USP39,UBE2I,PARK7,SLC25A37,ASPHD2,ZNF428,RAB4A,TRA2B,SUCLG2,TAF5L,CISD2,SMARCE1,ZNF800,CDC5L,ZNF524,SGCE,NSUN2,USP22,CLNS1A,EIF3A,ZMYM3,DOT1L,IWS1,ANKRD10,WAS,KIF18B,TPP2,C1orf109,ZMAT3,B4GALT2,PRPF38B,RECQL,C9orf78,EWSR1,GADD45G,RRM1,ACAP1,B4GALT1,CYCS,FAM136A,SUPT7L,TMEM165,NPLOC4,CNOT3,WDR48,SPAG5,RTKN,CEP104,EXOSC7,KLHL5,LRRC8D,PPP4R1,MSH2,PIGG,FBXL7,MRPL40,SYTL3,FAM171A1,APOL1,EIF5A,GCC2,PRIM2,ELL2,RDH10,MFNG,RPS24,GORASP2,CAPZA2,ADRB2,CCT8,MTR,PHF6,PFDN5,SLCO4A1,TTC13,GOLGA2,RBMX,MED15,PIAS2,APPL2,SAMD8,CDKN2A,NUDT3,ZNF511,ATXN3,RAF1,KIAA0232,C2orf49,EPM2A,CD320,CCNA2,MTMR4,BRI3,TP53BP2,AQR,RBM12B,ILKAP,CDK12,SAP30,BRD4,DRAP1,NARF,LRRC8A,ELP4,ABHD11,PKMYT1,ASB13,SERP1,TRIM28,SUPT16H,EIF3K,CHMP4A,CBWD1,ATF6,XRCC4,PRPF4B,ADAM23,NDUFS1,DEPDC1,MECP2,SECISBP2,HMG20A,WWP2,JAKMIP1,SLC25A36,DNAJC8,AXIN2,CITED2,JMJD4,ANKRD37,KAT2A,TMEM126B,RABIF,ADSL,BMS1,KCNQ1,ARSK,MACF1,KIF11,KLF6,COMMD4,SMAP2,FADD,SH3GLB1,MYO1F,CBX3,TMEM127,INF2,PPP1R11,DUSP11,DDX5,WDR62,TAF6,ESPL1,PURA,DDB1,DEF6,IPO4,FAM83G,UBL3,NAT9,PIGM,LYRM4,GPR132,UBE2Q1,PTP4A3,BRIX1,MRPL19,ZNF696,SF3B2,PCYOX1L,CDC42,SYNM,GOT2,JAZF1,HADHB,RPF2,SLC35C2,CNNM3,CARM1,SRPK2,WDR41,LARS,ZCCHC10,CCDC138,LRBA,SUMF2,KMT2C,PRPSAP1,ASF1B,RPL37,MAN2A2,EIF4ENIF1,NIP7,U2SURP,MIA2,ZNF268,ATP6V0E1,PPP1R2,PM20D2,XPNPEP3,RGS2,LYAR,FAM89B,POLR2I,TRAFD1,SUGP2,GBA,SYVN1,DAPK3,ARHGAP15,MASTL,UAP1,NFIL3,FN3KRP,YWHAZ,CTSA,TMEM14A,TOB1,TSEN15,ADNP2,TCF12,PRKAB1,MDH2,SMARCA4,RRN3,UBXN2A,IARS,CD3EAP,KIF14,EXOSC1,CS,CLTB,DNAL4,CSTF1,POU2AF1,UBQLN4,HPDL,PGGT1B,SELPLG,SMU1,ATXN1,GLO1,OGDH,BICD2,CADM1,EDEM2,HERPUD2,TOLLIP,FANCE,MBD3,PDHX,RPS9,ALKBH6,SURF4,DUS3L,ARNTL,ANP32E,FKBP5,TMEM101,CCDC125,ABCA1,PDCD2L,GCLM,RAE1,DCTN2,CHIC2,PAWR,MXD4,DCUN1D4,PIP4K2A,XPR1,FERMT3,KIF5B,KLHL20,SEC24C,RRBP1,ARHGEF2,LDLRAD3,STAT3,MYO5A,NIPAL3,AMPD2,TXNL1,PHF20L1,DCAF6,FAM49B,TMEM39A,ATP2C1,RFFL,COG1,RCOR1,PRMT2,TFEB,LEMD2,UPF1,ELMO1,ZC3H7B,DTX4,ZMIZ1,TERF1,HRAS,CCDC93,FGFR1OP,TMED7,PIGQ,AGPAT1,CNTROB,PPP1R16B,MIS12,GSDMB,TTC9C,PDS5B,SENP1,PGAP2,TMEM115,PLEKHM3,DCUN1D5,PLEKHF2,BRMS1,PWWP2B,TRIM47,WDR11,AXIN1,SMG9,TRIM52,LONP2,NDUFV2,PHF23,CERK,SLC4A2,EZH1,ITGB5,LMNA,FBRS,MCTS1,DDX56,EIF2S2,SLC38A5,FOXN2,CARS2,PRRC2A,C16orf72,RB1CC1,ZMYND11,PGS1,MYBL2,UHRF1BP1,SRSF5,MPG,MATR3,CYB5A,NCDN,POLR2J,SETD3,PTAR1,CNOT6,NDE1,EGLN1,ZNF207,ANKRD27,ABCA3,SARNP,IVNS1ABP,MON1B,RMI2,TMEM97,NIT2,NUF2,ZNF267,TCF19,TMEM161B,KTN1,APP,PRKD3,CLUAP1,ATP2A2,UTP18,DUT,ANAPC7,RNF19A,FAM76B,CLN6,TMEM9,GCC1,RNF169,ADCY7,ATP6V1G1,ENPP4,RNPS1,CDCA2,FKBP3,GPR137,DDX17,CHCHD3,PEX5,CDC16,HIPK2,MBOAT1,TICAM1,PDXK,ZBTB11,TMBIM4,GMCL1,UBE4A,IL21R,ETS1,WRB,ZNF92,PNO1,CAPN2,ADD3,SUV39H2,TTLL12,TPCN1,TMX1,LYPLA2,HNRNPM,LDHB,PPP3CA,NUDT8,POLK,JTB,EMP3,MTMR12,ZP3,PDE3B,KIF18A,CCDC6,WNT5B,MAPK6,C4orf46,LY75,SLC25A19,RGL1,PSAP,WDR76,IGBP1,FAF1,SNAPIN,COX15,THOC1,AGRN,GNPDA1,GPBP1L1,PPP1R15B,CSNK2A1,EBNA1BP2,GIT2,BIRC2,ATPAF1,DLG5,ABL2,XRCC2,ZFYVE27,MCMBP,PTPRK,CDC37,SP3,METTL1,EXOSC6,HARS,GMFB,ESYT1,ANLN,RAB5B,RHEB,DPYSL3,TBC1D17,TIMM13,CDCA4,TONSL,NRM,NAGLU,ACTB,ZNF45,TMUB1,CTCF,ASAH1,DOCK11,CRLF3,ASXL2,LRRC14,SLC27A4,AFF1,MDFIC,MAML1,CYTH1,NQO2,UTP15,EIF2AK1,EIF4G2,ZDHHC3,MOSPD3,ITPRIPL1,CDC27,SNAP23,TBPL1,PRMT7,KCTD7,NDUFA5,CYLD,UGP2,DYNLL1,COPE,HCFC1R1,ZADH2,GGPS1,RPAIN,RAD23A,SEC11A,PDK2,ATP6V0B,TNFAIP8,STRBP,DUS4L,MRPL34,PDCD2,SAP30L,SLC39A9,CLPTM1,RPL29,RPL35,BTG2,DNAJC9,MTMR6,FRAT2,NFATC2,KDM1B,ARL5B,USP36,CCDC127,MRPL2,ATP1A1,CLK3,PSMD3,MAFK,CEP55,NDUFA11,DNAJC17,ZNF436,NCOA1,SLC25A39,ZC3HC1,ZNF146,ATXN7L2,CDC40,GOLIM4,SMAP1,RRP15,DAP,GNE,SMC6,ARFIP2,NKRF,CHAC2,BZW2,WRNIP1,SS18L1,CENPM,PTGES3,CAMK2G,MLEC,ZNF202,PPWD1,FAM50B,RHOT2,NEU1,TPD52L2,GOLGA7,TWSG1,PGRMC1,GLG1,FAM126A,SPCS3,RPS6KC1,UBE2C,PPCS,NDUFB6,TMEM41B,ZDHHC8,PLXNA1,CCNB1,SLC20A1,COMMD6,ABHD14A,POLR3K,C14orf119,ASAP2,SNUPN,CNPY4,TFG,PLCL2,SEH1L,ATG9A,PBK,MKI67,DDX20,AMDHD2,GALNT7,SLC17A5,CCNF,FOXRED1,RBM47,PTER,WDR4,DHTKD1,TRAF5,HDAC2,PWWP2A,HSPH1,LIME1,MAPRE1,CHTF18,ADO,KIF23,SLC35B1,NOTCH2,PMF1,JMY,FKBP1A,SLC31A1,SNX18,ATIC,ATP6V0A2,PIKFYVE,RNF135,LPCAT1,EEF1D,TMED2,FTL,PHF10,DDX28,ZNF84,SIGMAR1,PIP4K2C,RIT1,PLEC,KDM3A,SF3A2,FAS,EPRS,ZNF777,TMEM54,QARS,PPP3R1,TCOF1,CABLES1,NRBP1,DNMT3A,RWDD1,CKLF,TRIP10,SF3B1,SUZ12,CAST,RAC1,GPR89A,GNB2,FLAD1,APLP2,KDM2A,CDKN1B,TNPO2,TALDO1,GPX4,ATP13A1,MAPRE2,RFC3,ERF,CUL3,SLBP,KIAA1586,H2AFV,GAR1,PSMB9,POLG2,DHX57,NSA2,HSPA4,MRPL55,JAK1,TBL3,SEL1L,H2AFX,KLHDC4,B4GALT3,PDCD11,ATMIN,POLQ,POU3F2,NCOR2,ANKRD13D,PKP4,SCAMP3,CDCA3,SLC25A12,BLM,TMCC3,GTF2F1,CRAT,AHSA1,PRC1,UPF2,COPS7B,SLC38A10,CNPY3,UBE2M,IFT46,TMEM160,TSHZ1,ZFP64,DENND4C,DENND1B,WDR18,RPL8,ILF3,LRRC1,RHOT1,MARK2,TSR2,ECH1,PRDX1,PLD3,NUCB1,FBXO21,GNA12,C1orf131,PRDX3,PFDN4,HNRNPH3,STX18,TFDP1,KHSRP,ASNA1,CPEB2,SSSCA1,BYSL,VPS29,S100PBP,MIB2,IER2,PTMS,NOP2,UBN1,DCAF15,NF1,FLYWCH2,ALKBH5,MOGS,TAF6L,MAPK14,BECN1,SNAPC4,RNF103,BCAT2,MBD4,C18orf32,METTL14,IMPAD1,ZNHIT6,RCSD1,PHTF1,SRI,KIF22,ZBTB22,NFU1,TRIM14,ELOF1,COPS8,FYTTD1,TRIM8,RRM2,SOX4,ABHD5,CXXC4,UBTF,UEVLD,SPATA2,PQBP1,IARS2,ATXN2L,GALNT10,STARD3NL,RPS15,PIGN,AGTRAP,CIB1,XPO7,SRRT,ZNF449,CAPZA1,GLTP,BCL2,KIFAP3,N4BP2,HP1BP3,THNSL1,ISG15,CAND1,GNAS,TSC1,RBM25,CDCA5,ZFP90,NANP,RBBP4,ZBTB24,SMARCD1,MBD1,WASF2,MMACHC,TOMM20,IFI27L1,GNPNAT1,MPHOSPH8,HNRNPUL2,CHD1,MEAF6,C2orf68,CCDC50,AKAP8,PARL,RPN2,CHTOP,FAM3A,F2R,TMEM14C,SCYL3,ABI1,HTRA2,MOSPD1,RLIM,FAM172A,ZNF500,PSMB7,NLN,WIPF1,BUD13,NDUFB1,PEF1,EIF3G,BTBD1,TAB2,CHCHD1,TULP3,WDR59,CANT1,SCARB1,GAS2,USP11,SMURF1,PPP2R2D,TSPAN5,CDS2,MAGEH1,MRPL42,EYA1,CDK2AP2,MRPS26,LETMD1,KLF13,HDDC2,RGS1,MAN1A1,FBXO5,GART,PELO,TANK,BRD7,MRPL11,SAMD4B,ZDHHC18,GTF3C6,POLR3GL,WDR81,MEN1,ZNF407,MFN2,COX8A,ZRANB2,MBD6,SRSF3,ATP6V1C1,IDH3B,TATDN1,TSC2,LACTB2,CMTM6,RBM4,ZNF275,ANKRD39,RPL23A,CDKN2C,USF1,MECR,AP1M1,UPRT,CRY2,ECD,RNF26,TIPARP,LRRC59,ANKRD9,RHBDD2,MGAT5,BAK1,ZNF559,RHOBTB3,GABPA,WBP1,ARF4,GINS4,KRIT1,BOLA3,AHNAK,RAD18,PDRG1,RNASEL,CHPF2,PDCD4,SMNDC1,HIVEP3,KIAA0100,CLSPN,RHOC,DHX9,PDCD7,PSMD9,HAUS2,COPB2,CD59,TFAP4,RNFT1,RIMS3,MEGF8,FBXO7,EFTUD2,CPSF4,MRPL21,PHKG2,LUC7L2,SRSF11,EIF3L,MTA2,TYW1,ITM2A,SSR2,BCLAF1,MTX1,SFXN5,FNTA,PDLIM1,TXNDC16,ZNF830,TMEM159,MRPL3,ALS2,FAM72A,TRIM41,KARS,NQO1,POC1A,ANK3,PTTG1,TPX2,TBC1D13,DAZAP2,STMN1,GLRX3,REPS1,ABHD16A,FBXL6,SH3BP1,MTA1,UBA5,CLCN6,INTS12,C8orf59,RPRD1B,CGGBP1,CPNE1,SEC61B,POLR2L,FAM118B,GOPC,E2F3,CIRBP,RPL38,CRNKL1,PFKFB3,GORAB,RAB1A,GIGYF1,TMEM184C,PPP2CA,KIF2A,CCDC14,LSM6,RNF38,SNRPG,DMWD,USP13,MZT1,ZFP91,TRMT6,IP6K2,WDR5,SLC25A43,IFT27,PMVK,NEIL2,RRP36,SRXN1,RPA2,PSMD2,CLIC4,PDCD10,CBWD2,COQ4,ITGB8,ARF5,ARHGEF1,FBXL19,TTPAL,UTP20,GPS2,DBI,SSNA1,MRFAP1L1,CD81,TMEM131,WDR13,FANCI,CREM,FANCL,GLIS2,IL6ST,POP7,SLC44A1,MTPN,ASB6,PLK1,RPP25,CELSR2,SEPT9,RBX1,APH1A,RAD51AP1,CKAP2L,PSMG1,UBE2V1,EAF2,IL12RB1,KRTCAP2,LUC7L,LSG1,NECAP2,C1orf122,TRIM4,AGPAT2,CHD3,ZNF367,E2F4,PRPF4,BEND6,CLN3,DNAJC30,NGLY1,POT1,MYL12B,CCDC137,RMND5A,HJURP,PHB2,DNAJB2,FAM53C,NKD2,SDC2,KLC1,CDK13,ADCK5,COX4I1,DNAJB1,RAB6A,ARID1B,C1GALT1,MLX,UBE2Q2,CCP110,ZNF746,ARL6IP1,CTR9,NIPSNAP1,ABHD2,DCAF8,ACSL3,LDB1,MAP4K3,ARMC8,NMT2,IRF5,RPL36,HAUS8,MBIP,COX7A2L,ZDHHC7,SIL1,FAM122A,DTD1,UNC13C,BCCIP,SART1,TRAF7,NDUFAF2,TOR1AIP1,ZNF416,LAGE3,ZFYVE21,TM9SF3,RRAGC,ZNF121,NRF1,WDR44,PIN1,EFCAB11,RPAP1,CABLES2,LMAN1,AHCYL1,TOP1MT,STRAP,SPSB3,ZNF583,SNX25,ARHGAP17,POLR2G,ZNF780B,PPT1,DCLRE1C,MRPS14,RHBDF2,SUGP1,RBL1,FASTK,UBXN2B,STK38,AP1S1,SPRYD4,SLC22A23,H3F3A,CHID1,SMAD4,RAD51D,SLC30A9,UNK,CMAS,NADSYN1,HMGN3,NCAPG,SCYL2,FZD6,HERC3,GTPBP3,CTSS,RNLS,YTHDC1,ACP2,HMGN5,CSRP1,METTL5,ABCF2,TUFM,RANGAP1,PNPLA8,HAGH,API5,ZFR,SEC23IP,E2F1,TMEM219,USP20,RBPJ,PDCD6IP,MAX,GXYLT1,LUZP1,ADAM10,CXXC1,TSC22D3,AP3M2,CUL1,GYG1,NANS,MYEF2,ANKRD26,NOL11,FIZ1,ZNF200,MARCH2,SLC26A2,SRP72,KLF10,LACTB,RFC2,CBFB,RAB2B,MAP3K4,HHEX,LUC7L3,RPS14,MAP4,MRPL27,BTF3,PTPDC1,NMD3,CCDC59,PTOV1,COX5B,DNAJC5,SCOC,DHPS,POLR2K,ANKH,VAV2,C16orf87,GSPT2,TATDN3,DLGAP4,PXMP2,PRPF39,PSEN1,ZNF79,PDXDC1,VPS25,NDUFS7,YY1AP1,C12orf10,FAM192A,RPN1,LHX8,ARPC5,ZNRF2,TPST1,DAPK1,PIK3IP1,CYC1,SOCS5,FDFT1,PIGT,EMB,WDR1,ZNF574,C1orf35,EXOSC9,ARID1A,PTTG1IP,C9orf40,FXR1,GOSR1,TWISTNB,AKAP1,XRCC5,HMGN2,PI4K2A,CAT,DERL1,MTHFD2,HSPBP1,ARAP1,USP32,FAM83D,CABIN1,SMPD4,GPI,CYTIP,TP53RK,REPS2,RAB11B,UROD,SLC39A13,POMP,BCL2L1,NUDT19,DECR1,RALB,SIAH1,ADCY9,LPIN2,MRPS27,SOCS6,TTC3,RNASEH2A,CFL1,ANKLE2,CDC123,VDAC2,EDF1,EML4,ERC1,AMZ2,ANKZF1,ZNF282,DSN1,DDOST,HINT1,DGCR8,SAFB,HAGHL,FTSJ1,RWDD4,LMBR1,NCLN,BEND3,EYA2,DYNC1LI2,MANBA,B4GALT5,SLC41A1,FAM76A,TKT,CBLL1,ARGLU1,LANCL1,POFUT1,FAM8A1,HEATR5B,HLA-A,EBP,RFWD3,NDUFA2,FUT8,BTF3L4,PTPN11,MRPL54,FEM1B,RPL19,CNN2,NDUFA3,MTX2,MSH6,PDLIM2,LONRF3,RFXANK,FBXO9,GUF1,RPL32,ZHX1,NDUFS5,WDR91,HIGD2A,GPR89B,ZBED3,RORB,POLA2,ZNF76,COPA,UQCR10,HMGXB3,ABCB10,COMMD5,MAP1LC3B,DST,RAB35,SIVA1,GPATCH1,DRAM2,DEAF1,SNRNP200,LAP3,NCK1,VHL,SREK1,ARHGDIB,PITPNB,HSPB11,BRWD1,PPM1G,SH3GLB2,CRCP,BAZ1B,CAB39,ACBD4,STK11,CLU,CHEK2,ZSWIM3,TSTD2,MRPL13,CHPT1,DCAF5,CAPN1,UBE2D3,NSMCE4A,PPP1R12A,ZCCHC8,GORASP1,NACA,UBXN1,RPL15,PCSK7,THRAP3,QSOX2,TTF1,PRPF18,CHKA,DTL,MED10,ZRANB1,MCPH1,SLC12A2,ATP6V0D1,CSNK1G3,CREG1,NUDT4,RPL6,VKORC1,SLTM,EVC2,KLHL15,SIAH2,SLC16A1,EHD4,SNRNP70,C11orf1,APOL2,N4BP2L2,SNX27,CHMP2A,CORO7,FEZ2,UCK2,PMS2,UCK1,CLCC1,EXT2,MXD1,USP5,HNRNPA2B1,SAP130,NVL,PPP6C,CYB5R1,ZNF770,EBAG9,RNF25,PCGF6,METTL2A,FAM72B,PON2,HNRNPR,STAT6,HPS5,MAPK1,BRD9,TMEM33,NAT14,DNAJC2,TRIP12,SHPRH,SCYL1,VPS45,GFM2,SPPL2A,FASTKD3,FGFR3,MZT2A,PPIG,ZDHHC13,TMEM99,H2AFY,NDUFS8,ATG13,ERI3,FBL,FRMD8,SLC35A1,MICAL3,TGFB1,B3GALT6,ELOVL5,HEMK1,TIMMDC1,HELB,PSPC1,MIER1,SCFD2,NDRG3,MTMR3,ACAT1,CENPT,PLOD3,RAB3IL1,RAB14,ADD1,KDM4A,MRPS15,XIAP,DHX8,GLUD1,ANKRD23,CDK5,CALM2,PSMD1,NEK6,NSRP1,RABGAP1L,SRSF4,FNIP2,KCNAB2,PCBP2,PLK3,ZNF672,MRPL43,HSDL1,TOPORS,MCL1,PPFIA3,SMC2,ICMT,SLC50A1,STOML2,LIMK1,ZNF689,PRDX5,ATE1,MLYCD,ST3GAL2,ATP6V0C,FBXL3,TFDP2,E2F2,PFKP,AAAS,DDX42,SSRP1,MRPL9,MRPS2,STRN4,TOP2B,ZNRF3,TMED3,DDRGK1,RAVER2,GNS,INTS7,INPP5A,MCM5,PHF14,ZNF326,NAGPA,TIMM8B,ETV3,TSPAN31,DHX29,TEX10,MAN1B1,RPS10,CBFA2T2,ABCF1,RHOB,LRRC14B,DTWD1,PTPRF,SCARB2,CCDC86,DUSP3,SLAIN1,MDH1,HEXA,RNF139,SNX14,ZNF296,TRERF1,UBR2,CHD1L,ACTR3,WDTC1,MYH9,CREBL2,NIPA2,PRKACA,SAFB2,STAM,ARL6IP6,RAB21,SP100,ZKSCAN1,DDA1,ANKRD13C,MAVS,CEP63,TMEM136,ATF2,RBM15,DCTN1,SHOC2,PSRC1,MAP4K4,WBP2,ATP6V0A1,DNAJA1,NDUFA7,TAZ,TAF2,SEC61A1,RPLP1,WDR7,CBLN2,RBMS1,FUS,GEN1,LRP8,COIL,LRCH1,GALK1,RPS2,SESTD1,TRAK1,JMJD6,SIKE1,AKT1S1,KRI1,FBXO3,ERH,GATC,PPP1R8,PRDM4,GTSE1,GEMIN6,DCP1A,SGCB,S100A6,IMPA2,NUDC,PDPK1,TK1,GUK1,TNFAIP3,GALC,ZNF512,KIAA0930,MRPS10,DDX39A,RPA1,ZNF180,ZNF862,KEAP1,POLE,TATDN2,PITX1,CAPN7,LRPPRC,PML,HMGB2,USF2,ANAPC4,SRM,DDX47,MCCC1,CDC42SE2,S1PR2,CDIPT,KCMF1,SSR1,LIN9,PCNA,ZNF639,TRMU,ETV6,PIK3R2,PPCDC,TXLNA,FAM86C1,MYBL1,MRPL32,CCAR1,ABCC5,PBXIP1,TLK1,MRPL12,EZR,LNX2,LRP5,BRCA1,PRKRA,STX16,EPB41,SEPT1,SOCS4,QRSL1,GLCCI1,NUDT11,GEMIN7,LZTR1,RACGAP1,PPP3CB,B4GALT4,RLF,RAPGEF6,SNRNP25,RB1,VASP,MED8,VMP1,PPIL2,MEA1,TIMELESS,AHDC1,ALDH18A1,TMEM8A,ABCC1,PREB,TRAPPC9,AACS,MEMO1,KRAS,RTF1,UBE4B,NFATC2IP,LY6E,ARPC1A,ZNF174,PSMC4,GOLGA4,SYNCRIP,PRPS2,NIPA1,TIGD2,RNF114,FOXM1,MRPL39,XAB2,DUSP22,COMMD8,RPL11,CSDE1,MDM2,CORO1A,MINPP1,METTL9,POC5,DVL2,GM2A,PSMA8,COQ10B,CPOX,TIGD5,SLC26A6,CYP20A1,PRPF3,TXNL4A,RPSA,SRSF1,DNAJC10,SCAP,ZNF700,PLEKHG4B,TIMM17A,FAU,LTA4H,AP2S1,USP53,CTDP1,MIF4GD,CDT1,ARID5A,SUMF1,GGA2,AP3S1,CSNK1A1,RMI1,TFRC,PTPN2,STARD9,IRF4,GSTK1,NDUFV1,SLC1A4,CWC27,SLC35B4,DDX31,ABCD1,RPAP3,CNTN5,SNX2,ZMYM5,CCDC34,CHCHD6,BSDC1,KPNA4,CDKN2AIPNL,FBXO41,BIRC5,TFE3,SNAP29,CDCA7L,PKD2,ACADM,CHMP7,SAT2,GCSH,ZNF496,TMEM109,TAP1,NHLRC3,IKBIP,EIF1B,ELMOD2,KIFC1,DBNDD1,RNASEK,CDC25B,PRADC1,DNMT1,NOL12,USO1,AKT2,NOL8,GNG7,AURKB,MCFD2,SLC25A5,ZFAND5,MAK16,STT3A,TMED10,PSMD8,EIF2D,ITGB1,PTPN7,UQCRH,RRS1,ARRB2,RTN3,SVIP,DDX58,WSB2,PPIB,MUT,GMFG,HLA-E,NDUFA4,MAN2B1,METTL3,CFLAR,NDUFS4,RNF121,MEX3C,KLF16,HDAC7,DAD1,BDH1,PCYT2,GNAI2,ANKHD1,TERF2,MORC3,KCTD20,SEPT8,DCTD,TOMM40,ADSS,SERTAD2,SERF2,ZFP92,NSF,DCK,ERGIC3,ACLY,LPCAT4,VCPIP1,YY1,PPP6R2,PPP6R3,MAP3K5,RNF14,CDK2,ZC3HAV1,SYS1,ZBTB37,URB2,EIF3D,MAGED1,KLHL18,ADPGK,SLC25A44,AP1B1,SDHA,PHC2,CRKL,MOAP1,TERF2IP,CYHR1,ZNF75D,SHC1,UCHL5,NAA35,TMBIM1,CCT2,CDKN2AIP,MKLN1,GALK2,CDC23,SHCBP1,AP4E1,PRDM11,VEZF1,PPP2R5A,ACYP1,STAT1,PPA2,TRIM32,RHEBL1,C1orf112,MRI1,TCF3,BRAP,AGPAT3,MYNN,SDF2L1,SPR,RAB11A,REEP5,FOXO3,MAD2L2,CCDC28A,PIP5K1C,RBM17,MAT2B,PTEN,CENPJ,TAGLN2,CREB1,SMC4,RNASEH2C,NEK7,NET1,PARP4,TBRG4,ANAPC2,RPL27A,YIF1A,SGSH,HGS,TTLL4,SLC38A7,MFAP1,CCDC69,BRWD3,ESYT2,SKA3,NPHP4,UBE2E2,HNRNPAB,PLXNC1,ST13,TMEM184B,DNAJC24,ZNF107,KIF2C,SLC29A1,AGFG1,SIRT2,FKBP2,USP48,SNRPD3,UBQLN2,CUTC,EDC3,UBLCP1,ZNF804A,RAP1A,THADA,EIF4A3,AP3S2,ATG3,DPYSL2,PPP1R12C,AKR1B1,NDUFB9,JOSD1,RP2,TTC4,TECR,ARID4A,FGFR1OP2,TIMM50,TDP1,DPM1,FOPNL,SLC16A7,WDR82,SLC25A22,STK17B,DHX15,CHAF1A,GEMIN5,COPS6,SASS6,RPS26,PSMC1,SLC12A7,TBC1D12,TM9SF4,ZNF768,UFC1,MED13L,TIA1,MEF2A,EPHX2,PITHD1,RHBDD1,NFATC3,BANF1,BUD31,ZNF335,YBX1,KNTC1,ACAD8,UBE3C,ZNF189,ALDH9A1,KDELR1,TSTA3,CIC,PSMA1,NAP1L1,EXOC4,KIAA1328,PITPNA,NAA20,PTDSS1,MZT2B,PDSS2,C7orf26,TMEM106C,IMMT,ASH1L,CHERP,WDYHV1,PLAGL2,CHKB,IRF3,TWF2,ANKRD28,FARSA,SAR1A,APOOL,PDIA6,ACSL5,TOR1AIP2,AZI2,GFER,RAD54B,TMEM41A,DAP3,ZNF317,GADD45B,AKNA,REEP4,CBX4,MIF,KIF3B,GOLPH3L,SH2D3A,CASP6,TOR3A,SRGN,DBF4,MFSD10,SAC3D1,CTNNBL1,YIF1B,CLDND1,TTC17,SLC25A1,GINS1,CSNK1G2,TELO2,ADAM17,HMGN1,NASP,ASPM,PRKAR1B,SYMPK,TARS,SNRPA,MAPK3,HSPA1B,HLA-B,ATAD2,PLAA,ZNF330,KBTBD7,PREPL |
| 3.410e-24 | -54.04 | classic | COSMIC cancer mutations | classic | 15207 | 2410 | 17385 | 2587 |
HECA,ZBTB10,ABCC10,HEXB,CCNL2,FBXO22,EEF2K,RAD23B,ATP13A3,DNM2,ZNRD1,FTSJ3,USP34,CCDC57,ERCC1,NRAS,EHMT1,KIF15,HNRNPF,WDHD1,MIER2,DIDO1,MCM2,RAB22A,SMAD2,MID1IP1,RPS27A,MPV17,COX5A,SMAD1,ZNF75A,ANXA11,SLC25A33,SEC61G,GGA1,MUM1,CCZ1,TRIO,CUTA,RAB23,KCTD17,HAUS4,EIF2AK4,APH1B,PARN,CDC73,MYL6B,ATG4A,TMEM179B,PDXP,SMC3,MVP,NSUN4,PPA1,IFRD1,AGGF1,FOXK1,RBM42,GTPBP4,MAP7D1,MRPL16,ELK1,EIF4H,RDH11,MAGED2,KPNA1,ETS2,TYW5,WIPI2,RUFY3,PDLIM5,ACSF2,EXOC3,RHOG,STARD7,C5orf30,VTI1A,SLC35B2,INO80E,LCLAT1,RCOR3,CPNE3,KIAA1147,RBM23,ZNF420,AHCTF1,TBC1D22A,TBC1D14,GMEB1,NSFL1C,SEPT11,GPD1L,ZC3H3,ARL5A,PDCL3,SNX8,ERMP1,EID1,IDH3A,POLR2D,HTATIP2,MEF2D,TMEM147,GSTCD,TANC1,MAT2A,VPS26B,NSMCE2,CORO1C,CAMKMT,PPP5C,PITRM1,TUBB,COMMD10,ZNF445,SRSF6,HABP4,CCM2,FLOT1,BTN3A1,ATG2B,ABHD14B,PPP1R3B,GOLM1,ZBTB45,HUWE1,ZNF260,NAA50,ANXA5,LTN1,UBE3B,NAP1L4,ZNF710,ST8SIA2,MED22,SPTAN1,STAU1,TCTEX1D2,DDX24,TACC1,MRS2,LDHA,HEBP2,LLPH,RAB3IP,TTC33,PICALM,SH3BP5,SLC19A1,ACOX1,FAM3C,AEN,PARP10,YWHAH,GPATCH4,FAM129A,TRIM11,YTHDC2,SNX15,RBM8A,ENSA,NENF,SND1,RUFY1,TRIM65,ZER1,PRNP,KRR1,RAB8A,NT5DC1,NOC2L,EIF5,TACC3,VPS13B,PTPN18,MIOS,SNRPB,MBLAC2,CDC6,UTP3,USP21,TRAM2,FBXO28,BCL7C,ARRDC1,ADAM9,DVL1,ZNF564,FUBP1,C1orf74,CTU2,PARP12,ZCCHC9,CENPF,LAMTOR3,CHCHD2,NCKAP1,LYRM2,RSAD1,TNS3,SUB1,RINL,SSBP3,MBD2,XPA,AHCY,RBM3,GLE1,LRSAM1,HDHD2,NTPCR,NSDHL,AMD1,CAMSAP1,ZNF761,METTL22,ICAM2,STYXL1,APPL1,BBS12,ANKRD46,RXRB,SDHB,PCM1,GALNT2,TMEM168,NLRC5,RUVBL2,BTBD10,MYO9A,CCNB2,USP7,GLT8D1,RPLP2,SUCLG1,ARID2,TMX4,SLC2A1,ATP6V1B2,PCBP1,LYN,BCAP31,VAV1,TMEM69,MRPL50,PSMA6,ZNF473,BRPF3,TARDBP,BCAP29,CTDSP2,PRPF19,PPIF,KDM3B,MND1,CLCN3,BIRC3,RAB7A,ANKRD33B,PPIE,CHMP2B,VDAC1,EIF3H,TMEM201,GLOD4,IDE,DHX16,UHRF2,XRCC3,CHMP4B,PARD3,BCL2L12,C19orf53,MCM10,KLHL21,PDAP1,CDCA8,TMX3,ARF1,SLC12A9,TUBGCP2,DNAJB9,HOMER1,POLR1B,RNF5,RBM15B,PPAN,RHOA,RPRD1A,BTAF1,TOP3A,ARHGEF12,PCGF1,DDX23,RAB18,CACNB1,PDCD6,ATP6V1D,L3MBTL3,FAM110A,NEIL3,CTBS,BBX,IMPDH1,TAF12,NR2F2,PGAM1,HIPK3,IFI16,TXN,H2AFZ,PNISR,TMEM203,PRKCSH,USP39,UBE2I,PARK7,SLC25A37,ASPHD2,ZNF428,RAB4A,TRA2B,SUCLG2,CISD2,TAF5L,SMARCE1,ZNF800,CDC5L,ZNF524,SGCE,NSUN2,USP22,CLNS1A,EIF3A,ZMYM3,DOT1L,IWS1,ANKRD10,WAS,KIF18B,TPP2,C1orf109,ZMAT3,B4GALT2,PRPF38B,RECQL,C9orf78,EWSR1,GADD45G,RRM1,ACAP1,B4GALT1,CYCS,FAM136A,SUPT7L,TMEM165,NPLOC4,CNOT3,WDR48,SPAG5,RTKN,CEP104,EXOSC7,KLHL5,LRRC8D,PPP4R1,MSH2,PIGG,FBXL7,MRPL40,SYTL3,FAM171A1,APOL1,EIF5A,GCC2,PRIM2,ELL2,RDH10,MFNG,RPS24,GORASP2,CAPZA2,ADRB2,CCT8,MTR,PHF6,PFDN5,SLCO4A1,TTC13,GOLGA2,RBMX,MED15,PIAS2,APPL2,SAMD8,NUDT3,CDKN2A,ZNF511,ATXN3,RAF1,KIAA0232,C2orf49,EPM2A,CD320,CCNA2,MTMR4,BRI3,TP53BP2,AQR,RBM12B,ILKAP,CDK12,SAP30,BRD4,DRAP1,NARF,LRRC8A,ELP4,ABHD11,PKMYT1,ASB13,SERP1,TRIM28,SUPT16H,EIF3K,CHMP4A,CBWD1,ATF6,XRCC4,ADAM23,PRPF4B,NDUFS1,DEPDC1,MECP2,SECISBP2,HMG20A,WWP2,SLC25A36,JAKMIP1,DNAJC8,AXIN2,CITED2,JMJD4,ANKRD37,KAT2A,TMEM126B,RABIF,ADSL,BMS1,KCNQ1,ARSK,MACF1,KIF11,KLF6,COMMD4,SMAP2,FADD,SH3GLB1,MYO1F,CBX3,TMEM127,INF2,PPP1R11,DUSP11,DDX5,WDR62,TAF6,ESPL1,PURA,DDB1,DEF6,IPO4,FAM83G,UBL3,NAT9,PIGM,LYRM4,GPR132,UBE2Q1,PTP4A3,BRIX1,MRPL19,ZNF696,SF3B2,PCYOX1L,CDC42,SYNM,GOT2,JAZF1,HADHB,RPF2,SLC35C2,CNNM3,CARM1,SRPK2,WDR41,LARS,ZCCHC10,CCDC138,LRBA,SUMF2,KMT2C,PRPSAP1,ASF1B,RPL37,MAN2A2,EIF4ENIF1,NIP7,U2SURP,MIA2,ZNF268,ATP6V0E1,PPP1R2,PM20D2,XPNPEP3,RGS2,LYAR,FAM89B,POLR2I,TRAFD1,SUGP2,GBA,SYVN1,DAPK3,ARHGAP15,MASTL,UAP1,NFIL3,FN3KRP,YWHAZ,CTSA,TMEM14A,TOB1,TSEN15,ADNP2,TCF12,PRKAB1,MDH2,SMARCA4,RRN3,UBXN2A,IARS,CD3EAP,KIF14,EXOSC1,CS,CLTB,DNAL4,CSTF1,POU2AF1,UBQLN4,HPDL,PGGT1B,SELPLG,SMU1,ATXN1,GLO1,OGDH,BICD2,CADM1,EDEM2,HERPUD2,TOLLIP,FANCE,MBD3,PDHX,RPS9,ALKBH6,SURF4,DUS3L,ARNTL,ANP32E,FKBP5,TMEM101,CCDC125,ABCA1,PDCD2L,GCLM,RAE1,DCTN2,CHIC2,PAWR,MXD4,DCUN1D4,PIP4K2A,XPR1,FERMT3,KIF5B,KLHL20,SEC24C,RRBP1,ARHGEF2,LDLRAD3,STAT3,MYO5A,NIPAL3,AMPD2,TXNL1,PHF20L1,DCAF6,FAM49B,TMEM39A,ATP2C1,RFFL,COG1,RCOR1,PRMT2,TFEB,LEMD2,UPF1,ELMO1,ZC3H7B,DTX4,ZMIZ1,TERF1,HRAS,CCDC93,FGFR1OP,TMED7,PIGQ,AGPAT1,CNTROB,PPP1R16B,MIS12,GSDMB,TTC9C,PDS5B,SENP1,PGAP2,TMEM115,PLEKHM3,DCUN1D5,PLEKHF2,BRMS1,PWWP2B,TRIM47,WDR11,AXIN1,SMG9,TRIM52,LONP2,NDUFV2,PHF23,CERK,SLC4A2,EZH1,ITGB5,LMNA,FBRS,MCTS1,DDX56,EIF2S2,SLC38A5,FOXN2,CARS2,PRRC2A,C16orf72,RB1CC1,ZMYND11,PGS1,MYBL2,UHRF1BP1,SRSF5,MPG,MATR3,CYB5A,NCDN,POLR2J,SETD3,PTAR1,CNOT6,NDE1,EGLN1,ZNF207,ANKRD27,ABCA3,SARNP,IVNS1ABP,MON1B,RMI2,TMEM97,NIT2,NUF2,ZNF267,TCF19,TMEM161B,KTN1,APP,PRKD3,CLUAP1,ATP2A2,UTP18,DUT,ANAPC7,RNF19A,FAM76B,CLN6,TMEM9,GCC1,RNF169,ADCY7,ATP6V1G1,ENPP4,RNPS1,CDCA2,FKBP3,GPR137,DDX17,CHCHD3,PEX5,CDC16,HIPK2,MBOAT1,TICAM1,PDXK,ZBTB11,TMBIM4,GMCL1,UBE4A,IL21R,ETS1,WRB,ZNF92,PNO1,CAPN2,ADD3,SUV39H2,TTLL12,TPCN1,TMX1,LYPLA2,HNRNPM,LDHB,PPP3CA,NUDT8,POLK,JTB,EMP3,MTMR12,ZP3,PDE3B,KIF18A,CCDC6,WNT5B,MAPK6,C4orf46,LY75,SLC25A19,RGL1,PSAP,WDR76,IGBP1,FAF1,SNAPIN,COX15,THOC1,AGRN,GNPDA1,GPBP1L1,PPP1R15B,CSNK2A1,EBNA1BP2,GIT2,BIRC2,ATPAF1,DLG5,ABL2,XRCC2,ZFYVE27,MCMBP,PTPRK,CDC37,METTL1,SP3,EXOSC6,HARS,GMFB,ESYT1,ANLN,RAB5B,RHEB,DPYSL3,TBC1D17,TIMM13,CDCA4,TONSL,NRM,NAGLU,ACTB,ZNF45,TMUB1,CTCF,ASAH1,DOCK11,CRLF3,ASXL2,LRRC14,SLC27A4,AFF1,MDFIC,MAML1,CYTH1,NQO2,UTP15,EIF2AK1,EIF4G2,ZDHHC3,MOSPD3,ITPRIPL1,CDC27,SNAP23,TBPL1,PRMT7,KCTD7,NDUFA5,CYLD,UGP2,DYNLL1,COPE,HCFC1R1,ZADH2,GGPS1,RPAIN,RAD23A,SEC11A,PDK2,ATP6V0B,TNFAIP8,STRBP,DUS4L,MRPL34,PDCD2,SAP30L,SLC39A9,CLPTM1,RPL29,RPL35,BTG2,DNAJC9,MTMR6,FRAT2,NFATC2,KDM1B,ARL5B,USP36,CCDC127,MRPL2,ATP1A1,CLK3,PSMD3,MAFK,CEP55,NDUFA11,DNAJC17,ZNF436,NCOA1,SLC25A39,ZC3HC1,ZNF146,ATXN7L2,CDC40,GOLIM4,SMAP1,RRP15,DAP,GNE,SMC6,ARFIP2,NKRF,CHAC2,BZW2,WRNIP1,SS18L1,CENPM,PTGES3,CAMK2G,MLEC,ZNF202,PPWD1,FAM50B,RHOT2,NEU1,TPD52L2,GOLGA7,TWSG1,GLG1,PGRMC1,FAM126A,SPCS3,RPS6KC1,UBE2C,PPCS,NDUFB6,TMEM41B,ZDHHC8,PLXNA1,CCNB1,SLC20A1,COMMD6,ABHD14A,POLR3K,C14orf119,ASAP2,SNUPN,CNPY4,TFG,PLCL2,SEH1L,ATG9A,PBK,MKI67,DDX20,AMDHD2,SLC17A5,GALNT7,CCNF,FOXRED1,RBM47,PTER,WDR4,DHTKD1,TRAF5,HDAC2,PWWP2A,HSPH1,LIME1,MAPRE1,CHTF18,ADO,KIF23,SLC35B1,NOTCH2,PMF1,JMY,FKBP1A,SLC31A1,SNX18,ATIC,ATP6V0A2,PIKFYVE,RNF135,LPCAT1,EEF1D,TMED2,FTL,PHF10,DDX28,ZNF84,SIGMAR1,PIP4K2C,RIT1,PLEC,KDM3A,SF3A2,FAS,EPRS,ZNF777,TMEM54,QARS,PPP3R1,TCOF1,CABLES1,NRBP1,DNMT3A,RWDD1,CKLF,TRIP10,SF3B1,SUZ12,CAST,RAC1,GPR89A,GNB2,FLAD1,APLP2,KDM2A,TNPO2,CDKN1B,TALDO1,GPX4,ATP13A1,RFC3,MAPRE2,ERF,CUL3,SLBP,KIAA1586,H2AFV,GAR1,PSMB9,POLG2,DHX57,NSA2,HSPA4,MRPL55,JAK1,TBL3,SEL1L,H2AFX,KLHDC4,B4GALT3,PDCD11,ATMIN,POLQ,POU3F2,NCOR2,ANKRD13D,PKP4,SCAMP3,CDCA3,SLC25A12,BLM,TMCC3,GTF2F1,CRAT,AHSA1,PRC1,UPF2,COPS7B,SLC38A10,CNPY3,UBE2M,IFT46,TMEM160,TSHZ1,ZFP64,DENND4C,DENND1B,WDR18,RPL8,ILF3,LRRC1,RHOT1,TSR2,MARK2,ECH1,PRDX1,PLD3,NUCB1,FBXO21,GNA12,C1orf131,PRDX3,PFDN4,HNRNPH3,STX18,TFDP1,KHSRP,ASNA1,CPEB2,SSSCA1,VPS29,BYSL,S100PBP,MIB2,IER2,PTMS,NOP2,UBN1,NF1,DCAF15,FLYWCH2,ALKBH5,MOGS,TAF6L,BECN1,MAPK14,SNAPC4,RNF103,BCAT2,MBD4,C18orf32,METTL14,IMPAD1,ZNHIT6,RCSD1,PHTF1,SRI,KIF22,ZBTB22,NFU1,TRIM14,ELOF1,COPS8,FYTTD1,TRIM8,RRM2,SOX4,ABHD5,UBTF,CXXC4,UEVLD,SPATA2,PQBP1,IARS2,ATXN2L,GALNT10,STARD3NL,RPS15,PIGN,AGTRAP,CIB1,XPO7,SRRT,ZNF449,CAPZA1,GLTP,BCL2,KIFAP3,N4BP2,HP1BP3,THNSL1,ISG15,CAND1,GNAS,TSC1,RBM25,CDCA5,ZFP90,NANP,RBBP4,ZBTB24,SMARCD1,MBD1,WASF2,MMACHC,TOMM20,IFI27L1,GNPNAT1,MPHOSPH8,HNRNPUL2,CHD1,MEAF6,C2orf68,CCDC50,AKAP8,PARL,RPN2,CHTOP,FAM3A,F2R,TMEM14C,SCYL3,ABI1,HTRA2,MOSPD1,RLIM,FAM172A,ZNF500,PSMB7,NLN,WIPF1,BUD13,NDUFB1,PEF1,EIF3G,BTBD1,TAB2,CHCHD1,TULP3,WDR59,CANT1,SCARB1,GAS2,USP11,SMURF1,TSPAN5,PPP2R2D,CDS2,MAGEH1,MRPL42,EYA1,CDK2AP2,MRPS26,LETMD1,KLF13,HDDC2,RGS1,MAN1A1,FBXO5,GART,PELO,TANK,BRD7,MRPL11,SAMD4B,ZDHHC18,GTF3C6,POLR3GL,WDR81,MEN1,ZNF407,MFN2,COX8A,ZRANB2,MBD6,SRSF3,ATP6V1C1,IDH3B,TATDN1,TSC2,LACTB2,CMTM6,RBM4,ZNF275,ANKRD39,RPL23A,CDKN2C,USF1,MECR,AP1M1,UPRT,CRY2,ECD,RNF26,TIPARP,LRRC59,ANKRD9,RHBDD2,MGAT5,BAK1,ZNF559,RHOBTB3,GABPA,WBP1,ARF4,GINS4,KRIT1,BOLA3,AHNAK,RAD18,PDRG1,RNASEL,CHPF2,PDCD4,SMNDC1,HIVEP3,KIAA0100,CLSPN,RHOC,DHX9,PDCD7,PSMD9,HAUS2,COPB2,TFAP4,CD59,RNFT1,MEGF8,RIMS3,FBXO7,EFTUD2,CPSF4,MRPL21,PHKG2,LUC7L2,SRSF11,EIF3L,MTA2,TYW1,ITM2A,SSR2,BCLAF1,MTX1,SFXN5,FNTA,PDLIM1,TXNDC16,ZNF830,TMEM159,MRPL3,ALS2,FAM72A,TRIM41,KARS,NQO1,POC1A,ANK3,PTTG1,TPX2,TBC1D13,DAZAP2,STMN1,GLRX3,REPS1,ABHD16A,FBXL6,SH3BP1,MTA1,UBA5,CLCN6,INTS12,C8orf59,RPRD1B,CGGBP1,CPNE1,SEC61B,POLR2L,FAM118B,GOPC,E2F3,CIRBP,RPL38,CRNKL1,PFKFB3,GORAB,RAB1A,GIGYF1,TMEM184C,PPP2CA,KIF2A,CCDC14,LSM6,RNF38,SNRPG,DMWD,USP13,MZT1,ZFP91,TRMT6,IP6K2,WDR5,SLC25A43,IFT27,PMVK,NEIL2,RRP36,SRXN1,RPA2,PSMD2,CLIC4,PDCD10,CBWD2,COQ4,ITGB8,ARF5,ARHGEF1,FBXL19,TTPAL,UTP20,GPS2,DBI,SSNA1,MRFAP1L1,CD81,TMEM131,WDR13,FANCI,CREM,FANCL,GLIS2,IL6ST,POP7,SLC44A1,MTPN,ASB6,PLK1,RPP25,SEPT9,CELSR2,RBX1,APH1A,RAD51AP1,CKAP2L,PSMG1,UBE2V1,EAF2,IL12RB1,KRTCAP2,LUC7L,LSG1,NECAP2,C1orf122,TRIM4,AGPAT2,CHD3,ZNF367,E2F4,PRPF4,BEND6,CLN3,DNAJC30,NGLY1,POT1,MYL12B,CCDC137,RMND5A,HJURP,PHB2,DNAJB2,FAM53C,NKD2,SDC2,KLC1,CDK13,ADCK5,COX4I1,DNAJB1,RAB6A,ARID1B,C1GALT1,MLX,UBE2Q2,CCP110,ZNF746,ARL6IP1,CTR9,NIPSNAP1,ABHD2,DCAF8,ACSL3,LDB1,MAP4K3,ARMC8,NMT2,IRF5,RPL36,HAUS8,MBIP,COX7A2L,ZDHHC7,SIL1,FAM122A,DTD1,UNC13C,BCCIP,SART1,TRAF7,NDUFAF2,TOR1AIP1,ZNF416,LAGE3,ZFYVE21,TM9SF3,RRAGC,ZNF121,NRF1,WDR44,PIN1,EFCAB11,RPAP1,CABLES2,LMAN1,AHCYL1,TOP1MT,STRAP,SPSB3,ZNF583,SNX25,ARHGAP17,POLR2G,ZNF780B,PPT1,DCLRE1C,MRPS14,RHBDF2,SUGP1,RBL1,FASTK,UBXN2B,STK38,AP1S1,SPRYD4,SLC22A23,H3F3A,CHID1,SMAD4,RAD51D,SLC30A9,CMAS,UNK,NADSYN1,HMGN3,NCAPG,SCYL2,FZD6,HERC3,GTPBP3,CTSS,RNLS,YTHDC1,ACP2,HMGN5,CSRP1,METTL5,ABCF2,TUFM,RANGAP1,PNPLA8,HAGH,API5,ZFR,SEC23IP,E2F1,TMEM219,USP20,RBPJ,PDCD6IP,MAX,GXYLT1,LUZP1,ADAM10,CXXC1,TSC22D3,AP3M2,CUL1,GYG1,NANS,MYEF2,ANKRD26,NOL11,FIZ1,ZNF200,MARCH2,SLC26A2,SRP72,KLF10,LACTB,RFC2,CBFB,RAB2B,MAP3K4,HHEX,LUC7L3,RPS14,MAP4,MRPL27,BTF3,PTPDC1,NMD3,CCDC59,PTOV1,COX5B,DNAJC5,SCOC,DHPS,POLR2K,ANKH,C16orf87,VAV2,GSPT2,TATDN3,DLGAP4,PXMP2,PRPF39,PSEN1,ZNF79,PDXDC1,VPS25,NDUFS7,YY1AP1,C12orf10,FAM192A,RPN1,LHX8,ARPC5,ZNRF2,TPST1,DAPK1,PIK3IP1,CYC1,SOCS5,FDFT1,PIGT,EMB,WDR1,ZNF574,C1orf35,EXOSC9,ARID1A,PTTG1IP,C9orf40,FXR1,GOSR1,TWISTNB,AKAP1,XRCC5,HMGN2,PI4K2A,CAT,DERL1,HSPBP1,MTHFD2,ARAP1,FAM83D,USP32,CABIN1,SMPD4,GPI,CYTIP,TP53RK,REPS2,RAB11B,UROD,SLC39A13,POMP,BCL2L1,NUDT19,DECR1,RALB,SIAH1,ADCY9,LPIN2,MRPS27,SOCS6,TTC3,RNASEH2A,CFL1,ANKLE2,CDC123,VDAC2,EDF1,EML4,ERC1,AMZ2,ANKZF1,ZNF282,DSN1,DDOST,HINT1,DGCR8,SAFB,HAGHL,FTSJ1,RWDD4,LMBR1,NCLN,BEND3,EYA2,DYNC1LI2,MANBA,SLC41A1,B4GALT5,FAM76A,TKT,CBLL1,ARGLU1,LANCL1,POFUT1,FAM8A1,HEATR5B,HLA-A,EBP,RFWD3,NDUFA2,FUT8,BTF3L4,PTPN11,MRPL54,FEM1B,RPL19,CNN2,NDUFA3,MTX2,MSH6,PDLIM2,LONRF3,RFXANK,FBXO9,GUF1,RPL32,ZHX1,NDUFS5,WDR91,GPR89B,HIGD2A,ZBED3,RORB,POLA2,ZNF76,COPA,UQCR10,HMGXB3,ABCB10,COMMD5,MAP1LC3B,DST,RAB35,SIVA1,GPATCH1,DRAM2,DEAF1,SNRNP200,LAP3,NCK1,VHL,SREK1,ARHGDIB,PITPNB,HSPB11,BRWD1,PPM1G,SH3GLB2,CRCP,BAZ1B,ACBD4,CAB39,STK11,CLU,CHEK2,ZSWIM3,TSTD2,MRPL13,CHPT1,DCAF5,CAPN1,UBE2D3,NSMCE4A,PPP1R12A,ZCCHC8,GORASP1,UBXN1,NACA,RPL15,PCSK7,THRAP3,QSOX2,TTF1,PRPF18,CHKA,DTL,MED10,ZRANB1,MCPH1,SLC12A2,ATP6V0D1,CSNK1G3,CREG1,NUDT4,RPL6,VKORC1,SLTM,EVC2,KLHL15,SIAH2,SLC16A1,EHD4,SNRNP70,C11orf1,APOL2,N4BP2L2,SNX27,CHMP2A,CORO7,FEZ2,UCK2,PMS2,UCK1,CLCC1,EXT2,MXD1,USP5,HNRNPA2B1,SAP130,NVL,PPP6C,CYB5R1,ZNF770,EBAG9,RNF25,PCGF6,METTL2A,FAM72B,PON2,HNRNPR,HPS5,STAT6,MAPK1,BRD9,TMEM33,NAT14,DNAJC2,TRIP12,SHPRH,SCYL1,VPS45,GFM2,SPPL2A,FASTKD3,FGFR3,MZT2A,PPIG,ZDHHC13,TMEM99,H2AFY,NDUFS8,ATG13,ERI3,FBL,SLC35A1,FRMD8,MICAL3,TGFB1,B3GALT6,ELOVL5,HEMK1,TIMMDC1,HELB,PSPC1,MIER1,SCFD2,NDRG3,MTMR3,ACAT1,CENPT,PLOD3,RAB3IL1,RAB14,ADD1,KDM4A,MRPS15,XIAP,DHX8,GLUD1,ANKRD23,CDK5,CALM2,PSMD1,NEK6,NSRP1,RABGAP1L,SRSF4,FNIP2,KCNAB2,PCBP2,PLK3,ZNF672,MRPL43,HSDL1,TOPORS,MCL1,PPFIA3,SMC2,ICMT,SLC50A1,STOML2,LIMK1,ZNF689,PRDX5,ATE1,MLYCD,ST3GAL2,ATP6V0C,FBXL3,TFDP2,E2F2,PFKP,AAAS,DDX42,SSRP1,MRPL9,MRPS2,STRN4,TOP2B,ZNRF3,TMED3,DDRGK1,RAVER2,GNS,INTS7,INPP5A,MCM5,PHF14,ZNF326,NAGPA,TIMM8B,ETV3,TSPAN31,DHX29,TEX10,MAN1B1,RPS10,CBFA2T2,ABCF1,RHOB,LRRC14B,DTWD1,PTPRF,SCARB2,CCDC86,DUSP3,SLAIN1,MDH1,HEXA,RNF139,SNX14,ZNF296,TRERF1,UBR2,CHD1L,ACTR3,WDTC1,MYH9,CREBL2,NIPA2,PRKACA,SAFB2,STAM,ARL6IP6,RAB21,SP100,ZKSCAN1,DDA1,ANKRD13C,MAVS,CEP63,TMEM136,ATF2,RBM15,DCTN1,SHOC2,PSRC1,MAP4K4,WBP2,ATP6V0A1,DNAJA1,NDUFA7,TAZ,TAF2,SEC61A1,RPLP1,WDR7,CBLN2,RBMS1,FUS,GEN1,LRP8,COIL,LRCH1,GALK1,RPS2,SESTD1,TRAK1,JMJD6,SIKE1,AKT1S1,KRI1,FBXO3,ERH,GATC,PPP1R8,PRDM4,GTSE1,GEMIN6,DCP1A,SGCB,S100A6,IMPA2,NUDC,PDPK1,TK1,GUK1,TNFAIP3,GALC,ZNF512,KIAA0930,MRPS10,DDX39A,RPA1,ZNF180,ZNF862,KEAP1,POLE,TATDN2,PITX1,CAPN7,LRPPRC,PML,HMGB2,USF2,ANAPC4,SRM,DDX47,MCCC1,CDC42SE2,S1PR2,CDIPT,KCMF1,SSR1,LIN9,PCNA,ZNF639,TRMU,ETV6,PIK3R2,TXLNA,PPCDC,FAM86C1,MYBL1,MRPL32,CCAR1,ABCC5,PBXIP1,TLK1,MRPL12,EZR,LNX2,LRP5,BRCA1,PRKRA,STX16,EPB41,SEPT1,SOCS4,QRSL1,GLCCI1,NUDT11,GEMIN7,LZTR1,RACGAP1,PPP3CB,B4GALT4,RLF,RAPGEF6,SNRNP25,RB1,VASP,MED8,VMP1,PPIL2,MEA1,TIMELESS,AHDC1,ALDH18A1,TMEM8A,ABCC1,PREB,TRAPPC9,AACS,MEMO1,KRAS,RTF1,UBE4B,NFATC2IP,LY6E,ARPC1A,ZNF174,PSMC4,GOLGA4,SYNCRIP,PRPS2,NIPA1,TIGD2,RNF114,FOXM1,MRPL39,XAB2,DUSP22,COMMD8,RPL11,CSDE1,MDM2,CORO1A,MINPP1,METTL9,POC5,DVL2,GM2A,PSMA8,COQ10B,CPOX,TIGD5,SLC26A6,CYP20A1,PRPF3,TXNL4A,RPSA,SRSF1,DNAJC10,SCAP,ZNF700,PLEKHG4B,TIMM17A,FAU,LTA4H,AP2S1,USP53,CTDP1,MIF4GD,CDT1,ARID5A,SUMF1,GGA2,AP3S1,CSNK1A1,RMI1,TFRC,PTPN2,IRF4,STARD9,GSTK1,NDUFV1,SLC1A4,CWC27,SLC35B4,DDX31,ABCD1,RPAP3,CNTN5,SNX2,ZMYM5,CCDC34,CHCHD6,BSDC1,KPNA4,CDKN2AIPNL,FBXO41,BIRC5,TFE3,SNAP29,CDCA7L,PKD2,ACADM,CHMP7,SAT2,GCSH,ZNF496,TMEM109,TAP1,NHLRC3,IKBIP,EIF1B,ELMOD2,KIFC1,DBNDD1,RNASEK,CDC25B,PRADC1,DNMT1,NOL12,USO1,AKT2,NOL8,GNG7,AURKB,MCFD2,SLC25A5,ZFAND5,MAK16,STT3A,TMED10,PSMD8,EIF2D,ITGB1,PTPN7,UQCRH,RRS1,ARRB2,RTN3,SVIP,DDX58,WSB2,PPIB,MUT,GMFG,HLA-E,NDUFA4,MAN2B1,METTL3,CFLAR,NDUFS4,RNF121,MEX3C,KLF16,HDAC7,DAD1,BDH1,PCYT2,GNAI2,ANKHD1,MORC3,TERF2,KCTD20,SEPT8,DCTD,TOMM40,ADSS,SERTAD2,SERF2,ZFP92,NSF,DCK,ERGIC3,ACLY,LPCAT4,VCPIP1,YY1,PPP6R2,MAP3K5,PPP6R3,RNF14,CDK2,ZC3HAV1,SYS1,ZBTB37,URB2,EIF3D,MAGED1,KLHL18,ADPGK,SLC25A44,AP1B1,SDHA,PHC2,CRKL,MOAP1,TERF2IP,CYHR1,ZNF75D,SHC1,UCHL5,NAA35,TMBIM1,CCT2,CDKN2AIP,MKLN1,GALK2,CDC23,SHCBP1,AP4E1,PRDM11,VEZF1,PPP2R5A,ACYP1,STAT1,PPA2,TRIM32,RHEBL1,C1orf112,TCF3,MRI1,BRAP,AGPAT3,MYNN,SDF2L1,SPR,RAB11A,REEP5,FOXO3,MAD2L2,CCDC28A,PIP5K1C,RBM17,MAT2B,PTEN,CENPJ,TAGLN2,CREB1,SMC4,RNASEH2C,NEK7,NET1,PARP4,TBRG4,ANAPC2,RPL27A,YIF1A,SGSH,HGS,TTLL4,SLC38A7,MFAP1,CCDC69,BRWD3,ESYT2,SKA3,NPHP4,UBE2E2,HNRNPAB,PLXNC1,ST13,TMEM184B,DNAJC24,ZNF107,KIF2C,SLC29A1,AGFG1,SIRT2,FKBP2,USP48,SNRPD3,UBQLN2,CUTC,EDC3,UBLCP1,ZNF804A,RAP1A,THADA,EIF4A3,AP3S2,ATG3,DPYSL2,PPP1R12C,AKR1B1,NDUFB9,JOSD1,RP2,TTC4,TECR,ARID4A,FGFR1OP2,TIMM50,TDP1,DPM1,FOPNL,SLC16A7,WDR82,SLC25A22,STK17B,DHX15,CHAF1A,GEMIN5,COPS6,SASS6,RPS26,PSMC1,SLC12A7,TBC1D12,TM9SF4,ZNF768,UFC1,MED13L,TIA1,MEF2A,EPHX2,PITHD1,RHBDD1,NFATC3,BANF1,ZNF335,BUD31,YBX1,KNTC1,ACAD8,UBE3C,ZNF189,ALDH9A1,KDELR1,TSTA3,CIC,PSMA1,NAP1L1,EXOC4,KIAA1328,PITPNA,NAA20,PTDSS1,MZT2B,PDSS2,C7orf26,TMEM106C,IMMT,ASH1L,CHERP,WDYHV1,PLAGL2,CHKB,IRF3,TWF2,ANKRD28,FARSA,SAR1A,APOOL,PDIA6,ACSL5,TOR1AIP2,AZI2,GFER,RAD54B,DAP3,TMEM41A,ZNF317,GADD45B,AKNA,REEP4,CBX4,MIF,KIF3B,GOLPH3L,SH2D3A,CASP6,TOR3A,SRGN,DBF4,MFSD10,SAC3D1,CTNNBL1,YIF1B,CLDND1,TTC17,SLC25A1,GINS1,CSNK1G2,TELO2,ADAM17,HMGN1,NASP,ASPM,PRKAR1B,SYMPK,TARS,SNRPA,MAPK3,HSPA1B,HLA-B,ATAD2,PLAA,ZNF330,KBTBD7,PREPL |
| 3.426e-24 | -54.03 | HNRNPU (heterogeneous nuclear ribonucleoprotein U) | protein interactions | 3192 | 524 | 178 | 17029 | 2761 |
DDX47,MAX,HNRNPAB,NOP2,MRPS15,YTHDC2,CUL1,USP39,EBNA1BP2,SND1,UBQLN2,BRIX1,UBE2I,PABPC4,RPL23A,KRR1,EIF4A3,NOC2L,TRA2B,FTSJ3,CDC5L,SRP72,SNRNP200,AATF,VHL,RIOX2,SREK1,AURKB,BRCA1,MCM2,SLC25A5,RFC2,RCC1L,DOT1L,UBTF,CDCA4,NIP7,ZNF689,RPS14,LUC7L3,MRPL27,BAZ1B,PRPF4,ACTB,RRS1,ARRB2,MRPL13,RPS26,CCDC137,RPS15,MRPS2,DHX9,RPL15,THRAP3,HAUS2,LMNA,LYAR,RPN1,MCM5,RBM34,PHF14,EFTUD2,RTCB,YBX1,MRPL48,PABPC1,HP1BP3,SRSF11,DHX29,RPS10,RPL6,GTPBP4,RPS24,ADRB2,SEPT7,ABCF1,MATR3,SF3A2,RHOB,ISG15,PHF6,RPL36,CAND1,MAGED2,SYNCRIP,CCDC86,TXNDC16,POLR2J,RUVBL2,ATP5F1A,SNRNP70,CDK2,HNRNPDL,CDKN2A,BCCIP,SART1,CYLD,RPLP2,IVNS1ABP,TRIP10,EIF3D,MYH9,CHD1,RPL11,MRPL50,HNRNPA2B1,MDM2,FBXL6,SHC1,NVL,UTP18,PIN1,MRPS27,TARDBP,LMAN1,CDKN2AIP,RPL35,RFC3,SMU1,RNPS1,CUL3,VDAC2,MRPS14,RPS9,FKBP3,RPSA,USP36,SRSF1,SUPT16H,DAP3,HNRNPR,DGCR8,TBL3,SAFB,RPLP1,FUS,PDCD11,SMURF1,UNK,RPS2,C19orf53,RRP15,MRPL42,NKRF,PNO1,GTF2F1,KRI1,RPA2,PTEN,HUWE1,RPL17,AHSA1,BTF3L4,PTPN11,DDX31,RPL19,FBL,STAU1,DDX24,FOCAD,WDR18,RPL8,ILF3,RPL27A,SNRPA,POLR2A,RPA1,UPF1,PDCD6,RPL32,HNRNPH3,PML,PGRMC1,DDX5,SRSF3,CD81,ESPL1,IFI16 |
| 4.341e-24 | -53.79 | MORF_PRKAG1 | MSigDB lists | MORF_PRKAG1 | 211 | 93 | 17377 | 2626 |
NUP188,ST13,PRKCSH,RAF1,SUMO2,TOR1AIP1,RAC1,AGPAT1,CSNK2A1,GLUD1,BECN1,SDHA,SSR1,USP5,TERF2IP,HNRNPA2B1,CYHR1,MTA1,TXLNA,CS,HADHB,RPN2,TCEA1,AHCYL1,KDM3B,SNRNP200,SEC61B,AATF,HMGN4,DRAP1,PKMYT1,ESYT1,MCFD2,RAB1A,SERP1,ALG3,DAP3,SMAD2,CHD3,PSMD3,ATXN2L,SCARB1,COPS6,B4GALT3,SMNDC1,CSNK1D,HDAC2,NCOR2,MRPL9,CIB1,SLC4A2,LANCL1,XPO7,AP3S1,PARN,SRRT,PDXDC1,CNOT3,EBP,TFAP4,RPA2,PSMD2,DNAJC8,HUWE1,MEA1,CAPZA1,NAP1L4,UBE3C,CPSF4,NIPSNAP1,CSNK1G2,MLEC,TSTA3,BMS1,MTX1,SEPT7,PCGF1,POLR2A,MFN2,YIF1A,SEC31A,EPRS,SEC23IP,PARG,LRPPRC,GLG1,COX8A,PPP1R11,NUP62,TCOF1,RUVBL2,DDB1,NUDT3 |
| 4.482e-24 | -53.76 | MORF_DDB1 | MSigDB lists | MORF_DDB1 | 233 | 99 | 17377 | 2626 |
NUP188,HNRNPAB,PRKCSH,RAF1,SUMO2,RAC1,AGPAT1,STARD7,CUL1,CSNK2A1,GLUD1,BECN1,SDHA,SSR1,USP5,TERF2IP,HNRNPA2B1,PIN1,TXLNA,CS,TCEA1,AHCYL1,KDM3B,SNRNP200,AATF,HMGN4,ATG9A,DRAP1,PKMYT1,ESYT1,RAB1A,MCM2,SERP1,ALG3,DAP3,SMAD2,CHD3,PSMD3,ATXN2L,PRPF4,SCARB1,COPS6,B4GALT3,SMNDC1,CSNK1D,SSRP1,NCOR2,PHB2,PDAP1,CIB1,SLC4A2,LANCL1,XPO7,PARN,PDXDC1,TUBGCP2,SRRT,CNOT3,EBP,TFAP4,RPA2,PSMD2,DNAJC8,HUWE1,MEA1,NAP1L4,UBE3C,CPSF4,CSNK1G2,MLEC,KAT2A,TSTA3,PRKDC,WDR18,BMS1,MTX1,SEPT7,PCGF1,ELK1,DDX39A,ABCF1,POLR2A,MFN2,YIF1A,SEC31A,EPRS,SEC23IP,PARG,LRPPRC,COX8A,PPP1R11,NUP62,RUVBL2,TCOF1,WDR62,IDH3B,CDK2,DDB1,NUDT3 |
| 4.853e-24 | -53.68 | medulla | COSMIC cancer mutations | medulla | 15211 | 2410 | 17385 | 2587 |
HECA,ZBTB10,ABCC10,HEXB,CCNL2,FBXO22,EEF2K,RAD23B,ATP13A3,DNM2,ZNRD1,FTSJ3,USP34,CCDC57,ERCC1,NRAS,EHMT1,KIF15,HNRNPF,WDHD1,MIER2,DIDO1,MCM2,RAB22A,SMAD2,MID1IP1,RPS27A,MPV17,COX5A,SMAD1,ZNF75A,ANXA11,SLC25A33,SEC61G,GGA1,MUM1,CCZ1,TRIO,CUTA,RAB23,KCTD17,HAUS4,EIF2AK4,APH1B,PARN,CDC73,MYL6B,ATG4A,TMEM179B,PDXP,SMC3,MVP,NSUN4,PPA1,IFRD1,AGGF1,FOXK1,RBM42,GTPBP4,MAP7D1,MRPL16,ELK1,EIF4H,RDH11,MAGED2,KPNA1,ETS2,TYW5,WIPI2,RUFY3,PDLIM5,ACSF2,EXOC3,RHOG,STARD7,C5orf30,VTI1A,SLC35B2,INO80E,LCLAT1,RCOR3,CPNE3,KIAA1147,RBM23,ZNF420,AHCTF1,TBC1D22A,TBC1D14,GMEB1,NSFL1C,SEPT11,GPD1L,ZC3H3,ARL5A,PDCL3,SNX8,ERMP1,EID1,IDH3A,POLR2D,HTATIP2,MEF2D,TMEM147,GSTCD,TANC1,MAT2A,VPS26B,CORO1C,NSMCE2,CAMKMT,PPP5C,PITRM1,TUBB,COMMD10,ZNF445,SRSF6,HABP4,CCM2,FLOT1,BTN3A1,ATG2B,ABHD14B,PPP1R3B,GOLM1,ZBTB45,HUWE1,ZNF260,NAA50,ANXA5,LTN1,UBE3B,NAP1L4,ZNF710,ST8SIA2,MED22,SPTAN1,STAU1,TCTEX1D2,DDX24,TACC1,MRS2,LDHA,HEBP2,LLPH,RAB3IP,TTC33,PICALM,SH3BP5,SLC19A1,ACOX1,FAM3C,AEN,PARP10,YWHAH,GPATCH4,FAM129A,TRIM11,YTHDC2,SNX15,RBM8A,ENSA,NENF,SND1,RUFY1,TRIM65,ZER1,PRNP,KRR1,RAB8A,NT5DC1,NOC2L,EIF5,TACC3,VPS13B,PTPN18,MIOS,MBLAC2,SNRPB,CDC6,UTP3,USP21,TRAM2,FBXO28,BCL7C,ARRDC1,ADAM9,DVL1,ZNF564,FUBP1,C1orf74,CTU2,PARP12,ZCCHC9,CENPF,LAMTOR3,CHCHD2,NCKAP1,LYRM2,RSAD1,TNS3,SUB1,RINL,SSBP3,MBD2,XPA,AHCY,RBM3,GLE1,LRSAM1,HDHD2,NTPCR,NSDHL,AMD1,CAMSAP1,ZNF761,METTL22,ICAM2,STYXL1,APPL1,BBS12,ANKRD46,RXRB,SDHB,PCM1,GALNT2,TMEM168,NLRC5,RUVBL2,BTBD10,MYO9A,CCNB2,USP7,GLT8D1,RPLP2,SUCLG1,ARID2,TMX4,SLC2A1,ATP6V1B2,PCBP1,LYN,BCAP31,VAV1,TMEM69,MRPL50,PSMA6,ZNF473,BRPF3,TARDBP,BCAP29,CTDSP2,PRPF19,PPIF,KDM3B,MND1,CLCN3,BIRC3,RAB7A,ANKRD33B,PPIE,CHMP2B,VDAC1,EIF3H,TMEM201,GLOD4,IDE,DHX16,UHRF2,CHMP4B,XRCC3,PARD3,BCL2L12,MCM10,C19orf53,KLHL21,PDAP1,CDCA8,TMX3,ARF1,SLC12A9,TUBGCP2,DNAJB9,HOMER1,POLR1B,RNF5,RBM15B,PPAN,RHOA,RPRD1A,BTAF1,TOP3A,ARHGEF12,PCGF1,DDX23,RAB18,CACNB1,PDCD6,ATP6V1D,L3MBTL3,FAM110A,NEIL3,CTBS,BBX,IMPDH1,TAF12,NR2F2,PGAM1,HIPK3,IFI16,TXN,H2AFZ,PNISR,TMEM203,PRKCSH,USP39,UBE2I,PARK7,SLC25A37,ASPHD2,ZNF428,RAB4A,TRA2B,SUCLG2,TAF5L,CISD2,SMARCE1,ZNF800,CDC5L,ZNF524,SGCE,NSUN2,USP22,CLNS1A,EIF3A,ZMYM3,DOT1L,IWS1,ANKRD10,WAS,KIF18B,TPP2,C1orf109,ZMAT3,B4GALT2,PRPF38B,RECQL,C9orf78,EWSR1,GADD45G,RRM1,ACAP1,B4GALT1,CYCS,FAM136A,SUPT7L,TMEM165,NPLOC4,CNOT3,WDR48,SPAG5,RTKN,CEP104,EXOSC7,KLHL5,LRRC8D,PPP4R1,MSH2,PIGG,FBXL7,MRPL40,SYTL3,FAM171A1,APOL1,EIF5A,GCC2,PRIM2,ELL2,RDH10,MFNG,RPS24,GORASP2,CAPZA2,ADRB2,CCT8,MTR,PHF6,PFDN5,SLCO4A1,TTC13,GOLGA2,RBMX,MED15,PIAS2,APPL2,SAMD8,NUDT3,CDKN2A,ZNF511,ATXN3,RAF1,KIAA0232,C2orf49,EPM2A,CD320,CCNA2,MTMR4,BRI3,TP53BP2,AQR,RBM12B,ILKAP,CDK12,SAP30,BRD4,DRAP1,NARF,LRRC8A,ELP4,ABHD11,PKMYT1,ASB13,SERP1,TRIM28,SUPT16H,EIF3K,CHMP4A,CBWD1,ATF6,XRCC4,PRPF4B,ADAM23,NDUFS1,DEPDC1,MECP2,SECISBP2,HMG20A,WWP2,JAKMIP1,SLC25A36,DNAJC8,AXIN2,CITED2,JMJD4,ANKRD37,KAT2A,TMEM126B,RABIF,ADSL,BMS1,KCNQ1,ARSK,MACF1,KIF11,COMMD4,KLF6,SMAP2,FADD,SH3GLB1,MYO1F,CBX3,TMEM127,INF2,PPP1R11,DUSP11,DDX5,WDR62,TAF6,ESPL1,PURA,DDB1,DEF6,IPO4,FAM83G,UBL3,NAT9,PIGM,LYRM4,GPR132,UBE2Q1,PTP4A3,BRIX1,MRPL19,ZNF696,SF3B2,PCYOX1L,CDC42,SYNM,GOT2,JAZF1,HADHB,RPF2,SLC35C2,CNNM3,CARM1,SRPK2,WDR41,LARS,ZCCHC10,CCDC138,LRBA,SUMF2,KMT2C,PRPSAP1,ASF1B,RPL37,MAN2A2,EIF4ENIF1,NIP7,U2SURP,MIA2,ZNF268,ATP6V0E1,PPP1R2,PM20D2,XPNPEP3,RGS2,LYAR,FAM89B,POLR2I,TRAFD1,SUGP2,GBA,SYVN1,DAPK3,ARHGAP15,MASTL,UAP1,NFIL3,FN3KRP,YWHAZ,CTSA,TMEM14A,TOB1,TSEN15,ADNP2,TCF12,PRKAB1,MDH2,SMARCA4,RRN3,UBXN2A,IARS,CD3EAP,KIF14,EXOSC1,CS,CLTB,DNAL4,CSTF1,POU2AF1,UBQLN4,HPDL,PGGT1B,SELPLG,SMU1,ATXN1,GLO1,OGDH,BICD2,CADM1,EDEM2,HERPUD2,TOLLIP,FANCE,MBD3,PDHX,RPS9,ALKBH6,SURF4,DUS3L,ARNTL,ANP32E,FKBP5,TMEM101,CCDC125,ABCA1,PDCD2L,GCLM,RAE1,DCTN2,CHIC2,PAWR,MXD4,DCUN1D4,PIP4K2A,XPR1,FERMT3,KIF5B,KLHL20,SEC24C,RRBP1,ARHGEF2,LDLRAD3,STAT3,MYO5A,NIPAL3,AMPD2,TXNL1,PHF20L1,DCAF6,FAM49B,TMEM39A,ATP2C1,RFFL,COG1,RCOR1,PRMT2,TFEB,LEMD2,UPF1,ELMO1,ZC3H7B,DTX4,ZMIZ1,TERF1,HRAS,CCDC93,FGFR1OP,TMED7,PIGQ,AGPAT1,CNTROB,PPP1R16B,MIS12,GSDMB,TTC9C,PDS5B,SENP1,PGAP2,TMEM115,PLEKHM3,DCUN1D5,PLEKHF2,BRMS1,PWWP2B,TRIM47,WDR11,AXIN1,SMG9,TRIM52,LONP2,NDUFV2,PHF23,CERK,SLC4A2,EZH1,ITGB5,LMNA,FBRS,MCTS1,DDX56,EIF2S2,SLC38A5,FOXN2,CARS2,PRRC2A,C16orf72,RB1CC1,ZMYND11,PGS1,MYBL2,UHRF1BP1,SRSF5,MPG,MATR3,CYB5A,NCDN,POLR2J,SETD3,PTAR1,CNOT6,NDE1,EGLN1,ZNF207,ANKRD27,ABCA3,SARNP,IVNS1ABP,MON1B,RMI2,TMEM97,NIT2,NUF2,ZNF267,TCF19,TMEM161B,KTN1,APP,PRKD3,CLUAP1,ATP2A2,UTP18,DUT,ANAPC7,RNF19A,FAM76B,CLN6,TMEM9,GCC1,RNF169,ADCY7,ATP6V1G1,ENPP4,RNPS1,CDCA2,FKBP3,GPR137,DDX17,CHCHD3,PEX5,CDC16,HIPK2,MBOAT1,TICAM1,PDXK,ZBTB11,TMBIM4,GMCL1,UBE4A,IL21R,ETS1,WRB,ZNF92,PNO1,CAPN2,ADD3,SUV39H2,TTLL12,TPCN1,TMX1,LYPLA2,HNRNPM,LDHB,PPP3CA,NUDT8,POLK,JTB,EMP3,MTMR12,ZP3,PDE3B,KIF18A,CCDC6,WNT5B,MAPK6,C4orf46,LY75,SLC25A19,RGL1,PSAP,WDR76,IGBP1,FAF1,SNAPIN,COX15,AGRN,THOC1,GNPDA1,GPBP1L1,PPP1R15B,CSNK2A1,EBNA1BP2,GIT2,BIRC2,ATPAF1,DLG5,ABL2,XRCC2,ZFYVE27,MCMBP,PTPRK,CDC37,SP3,METTL1,EXOSC6,HARS,GMFB,ESYT1,ANLN,RAB5B,RHEB,DPYSL3,TBC1D17,TIMM13,CDCA4,TONSL,NRM,NAGLU,ACTB,ZNF45,TMUB1,CTCF,ASAH1,DOCK11,CRLF3,ASXL2,LRRC14,SLC27A4,AFF1,MDFIC,MAML1,CYTH1,NQO2,UTP15,EIF2AK1,EIF4G2,ZDHHC3,MOSPD3,ITPRIPL1,CDC27,SNAP23,TBPL1,PRMT7,KCTD7,NDUFA5,CYLD,UGP2,DYNLL1,COPE,HCFC1R1,ZADH2,GGPS1,RPAIN,RAD23A,SEC11A,PDK2,ATP6V0B,STRBP,TNFAIP8,DUS4L,MRPL34,PDCD2,SAP30L,SLC39A9,CLPTM1,RPL29,RPL35,BTG2,DNAJC9,MTMR6,FRAT2,NFATC2,KDM1B,ARL5B,USP36,CCDC127,MRPL2,ATP1A1,CLK3,PSMD3,MAFK,CEP55,NDUFA11,DNAJC17,ZNF436,NCOA1,SLC25A39,ZC3HC1,ZNF146,ATXN7L2,CDC40,GOLIM4,SMAP1,RRP15,DAP,GNE,SMC6,ARFIP2,NKRF,CHAC2,BZW2,WRNIP1,SS18L1,CENPM,PTGES3,CAMK2G,MLEC,ZNF202,PPWD1,FAM50B,RHOT2,NEU1,TPD52L2,GOLGA7,TWSG1,GLG1,PGRMC1,FAM126A,SPCS3,RPS6KC1,UBE2C,PPCS,NDUFB6,TMEM41B,ZDHHC8,PLXNA1,CCNB1,SLC20A1,COMMD6,ABHD14A,POLR3K,C14orf119,ASAP2,SNUPN,CNPY4,TFG,PLCL2,SEH1L,ATG9A,PBK,MKI67,DDX20,AMDHD2,GALNT7,SLC17A5,CCNF,FOXRED1,RBM47,PTER,WDR4,DHTKD1,TRAF5,HDAC2,PWWP2A,HSPH1,LIME1,MAPRE1,CHTF18,ADO,KIF23,SLC35B1,NOTCH2,PMF1,JMY,FKBP1A,SLC31A1,SNX18,ATIC,ATP6V0A2,PIKFYVE,RNF135,LPCAT1,EEF1D,TMED2,PHF10,FTL,DDX28,ZNF84,SIGMAR1,PIP4K2C,RIT1,PLEC,KDM3A,SF3A2,FAS,EPRS,ZNF777,TMEM54,QARS,PPP3R1,TCOF1,CABLES1,NRBP1,DNMT3A,RWDD1,CKLF,TRIP10,SF3B1,CAST,SUZ12,RAC1,GPR89A,GNB2,FLAD1,APLP2,KDM2A,TNPO2,CDKN1B,TALDO1,GPX4,ATP13A1,RFC3,MAPRE2,ERF,CUL3,SLBP,KIAA1586,H2AFV,GAR1,PSMB9,POLG2,DHX57,NSA2,HSPA4,MRPL55,JAK1,TBL3,SEL1L,H2AFX,KLHDC4,B4GALT3,PDCD11,ATMIN,POLQ,POU3F2,NCOR2,ANKRD13D,PKP4,SCAMP3,CDCA3,SLC25A12,BLM,TMCC3,GTF2F1,CRAT,AHSA1,PRC1,UPF2,COPS7B,SLC38A10,CNPY3,UBE2M,IFT46,TMEM160,TSHZ1,ZFP64,DENND4C,DENND1B,WDR18,RPL8,ILF3,LRRC1,RHOT1,TSR2,MARK2,ECH1,PRDX1,PLD3,NUCB1,FBXO21,GNA12,C1orf131,PRDX3,PFDN4,HNRNPH3,STX18,TFDP1,KHSRP,ASNA1,CPEB2,SSSCA1,BYSL,VPS29,S100PBP,MIB2,IER2,PTMS,NOP2,UBN1,NF1,DCAF15,FLYWCH2,ALKBH5,MOGS,TAF6L,MAPK14,BECN1,SNAPC4,RNF103,BCAT2,MBD4,C18orf32,METTL14,ZNHIT6,IMPAD1,RCSD1,PHTF1,SRI,KIF22,ZBTB22,NFU1,TRIM14,ELOF1,COPS8,FYTTD1,TRIM8,RRM2,SOX4,ABHD5,CXXC4,UBTF,UEVLD,SPATA2,PQBP1,IARS2,ATXN2L,GALNT10,STARD3NL,RPS15,PIGN,AGTRAP,CIB1,XPO7,SRRT,ZNF449,CAPZA1,GLTP,BCL2,KIFAP3,N4BP2,HP1BP3,THNSL1,ISG15,CAND1,GNAS,TSC1,RBM25,CDCA5,ZFP90,NANP,RBBP4,ZBTB24,SMARCD1,MBD1,WASF2,MMACHC,TOMM20,IFI27L1,GNPNAT1,MPHOSPH8,HNRNPUL2,CHD1,MEAF6,C2orf68,CCDC50,AKAP8,PARL,RPN2,CHTOP,FAM3A,F2R,TMEM14C,SCYL3,ABI1,HTRA2,MOSPD1,RLIM,FAM172A,ZNF500,PSMB7,NLN,WIPF1,BUD13,NDUFB1,PEF1,EIF3G,BTBD1,TAB2,CHCHD1,TULP3,WDR59,CANT1,SCARB1,GAS2,USP11,SMURF1,PPP2R2D,TSPAN5,CDS2,MAGEH1,MRPL42,EYA1,CDK2AP2,MRPS26,LETMD1,KLF13,HDDC2,RGS1,MAN1A1,FBXO5,GART,PELO,TANK,BRD7,MRPL11,SAMD4B,ZDHHC18,GTF3C6,POLR3GL,WDR81,MEN1,ZNF407,MFN2,COX8A,ZRANB2,MBD6,SRSF3,ATP6V1C1,IDH3B,TATDN1,TSC2,LACTB2,CMTM6,RBM4,ZNF275,ANKRD39,RPL23A,CDKN2C,USF1,MECR,AP1M1,UPRT,CRY2,ECD,RNF26,TIPARP,LRRC59,ANKRD9,RHBDD2,MGAT5,BAK1,ZNF559,RHOBTB3,GABPA,WBP1,ARF4,GINS4,KRIT1,BOLA3,AHNAK,RAD18,PDRG1,RNASEL,CHPF2,PDCD4,SMNDC1,HIVEP3,KIAA0100,CLSPN,RHOC,DHX9,PDCD7,PSMD9,HAUS2,COPB2,TFAP4,CD59,RNFT1,RIMS3,MEGF8,EFTUD2,FBXO7,CPSF4,MRPL21,PHKG2,LUC7L2,SRSF11,EIF3L,MTA2,TYW1,ITM2A,SSR2,BCLAF1,MTX1,SFXN5,FNTA,PDLIM1,TXNDC16,ZNF830,TMEM159,MRPL3,ALS2,FAM72A,TRIM41,KARS,NQO1,POC1A,ANK3,PTTG1,TPX2,TBC1D13,DAZAP2,STMN1,GLRX3,REPS1,ABHD16A,FBXL6,SH3BP1,MTA1,UBA5,CLCN6,INTS12,C8orf59,RPRD1B,CGGBP1,CPNE1,SEC61B,POLR2L,FAM118B,GOPC,E2F3,CIRBP,RPL38,CRNKL1,PFKFB3,GORAB,RAB1A,GIGYF1,TMEM184C,PPP2CA,KIF2A,CCDC14,LSM6,RNF38,SNRPG,DMWD,USP13,MZT1,ZFP91,TRMT6,IP6K2,WDR5,SLC25A43,IFT27,PMVK,NEIL2,RRP36,SRXN1,RPA2,PSMD2,CLIC4,PDCD10,CBWD2,COQ4,ITGB8,ARF5,ARHGEF1,FBXL19,TTPAL,UTP20,GPS2,DBI,SSNA1,MRFAP1L1,CD81,TMEM131,WDR13,FANCI,CREM,FANCL,GLIS2,IL6ST,POP7,SLC44A1,MTPN,ASB6,PLK1,RPP25,CELSR2,SEPT9,RBX1,APH1A,RAD51AP1,CKAP2L,PSMG1,UBE2V1,EAF2,IL12RB1,KRTCAP2,LUC7L,LSG1,NECAP2,C1orf122,TRIM4,AGPAT2,CHD3,ZNF367,E2F4,PRPF4,BEND6,CLN3,DNAJC30,NGLY1,POT1,MYL12B,CCDC137,RMND5A,HJURP,PHB2,DNAJB2,FAM53C,NKD2,SDC2,KLC1,CDK13,ADCK5,COX4I1,DNAJB1,RAB6A,ARID1B,C1GALT1,MLX,UBE2Q2,CCP110,ZNF746,ARL6IP1,CTR9,NIPSNAP1,ABHD2,DCAF8,ACSL3,LDB1,MAP4K3,ARMC8,NMT2,IRF5,RPL36,HAUS8,MBIP,COX7A2L,ZDHHC7,SIL1,FAM122A,DTD1,UNC13C,BCCIP,SART1,TRAF7,NDUFAF2,TOR1AIP1,ZNF416,LAGE3,ZFYVE21,TM9SF3,RRAGC,ZNF121,NRF1,WDR44,PIN1,EFCAB11,RPAP1,CABLES2,LMAN1,AHCYL1,TOP1MT,STRAP,SPSB3,ZNF583,SNX25,ARHGAP17,POLR2G,ZNF780B,PPT1,DCLRE1C,MRPS14,RHBDF2,SUGP1,RBL1,FASTK,UBXN2B,STK38,AP1S1,SPRYD4,SLC22A23,H3F3A,CHID1,SMAD4,RAD51D,SLC30A9,CMAS,UNK,NADSYN1,HMGN3,NCAPG,SCYL2,FZD6,HERC3,GTPBP3,CTSS,RNLS,YTHDC1,ACP2,HMGN5,CSRP1,METTL5,ABCF2,TUFM,RANGAP1,PNPLA8,HAGH,API5,ZFR,SEC23IP,E2F1,TMEM219,USP20,RBPJ,PDCD6IP,MAX,LUZP1,GXYLT1,ADAM10,CXXC1,TSC22D3,AP3M2,CUL1,GYG1,NANS,MYEF2,ANKRD26,NOL11,FIZ1,ZNF200,MARCH2,SLC26A2,SRP72,KLF10,LACTB,RFC2,CBFB,RAB2B,MAP3K4,HHEX,LUC7L3,RPS14,MAP4,MRPL27,BTF3,PTPDC1,NMD3,CCDC59,PTOV1,COX5B,DNAJC5,SCOC,DHPS,POLR2K,ANKH,C16orf87,VAV2,GSPT2,TATDN3,DLGAP4,PXMP2,PRPF39,PSEN1,ZNF79,PDXDC1,VPS25,NDUFS7,YY1AP1,C12orf10,FAM192A,RPN1,LHX8,ARPC5,ZNRF2,TPST1,DAPK1,PIK3IP1,CYC1,SOCS5,FDFT1,PIGT,EMB,WDR1,ZNF574,C1orf35,EXOSC9,ARID1A,PTTG1IP,C9orf40,FXR1,GOSR1,TWISTNB,AKAP1,XRCC5,HMGN2,PI4K2A,CAT,DERL1,HSPBP1,MTHFD2,ARAP1,USP32,FAM83D,CABIN1,SMPD4,GPI,CYTIP,TP53RK,REPS2,RAB11B,UROD,SLC39A13,POMP,BCL2L1,NUDT19,DECR1,RALB,SIAH1,ADCY9,LPIN2,MRPS27,SOCS6,TTC3,RNASEH2A,CFL1,ANKLE2,CDC123,VDAC2,EDF1,EML4,ERC1,AMZ2,ANKZF1,ZNF282,DSN1,DDOST,HINT1,DGCR8,SAFB,HAGHL,FTSJ1,RWDD4,LMBR1,NCLN,BEND3,EYA2,DYNC1LI2,MANBA,B4GALT5,SLC41A1,FAM76A,TKT,CBLL1,ARGLU1,LANCL1,POFUT1,FAM8A1,HEATR5B,HLA-A,EBP,RFWD3,NDUFA2,FUT8,BTF3L4,PTPN11,MRPL54,FEM1B,RPL19,CNN2,NDUFA3,MTX2,MSH6,PDLIM2,LONRF3,RFXANK,FBXO9,GUF1,RPL32,ZHX1,NDUFS5,WDR91,GPR89B,HIGD2A,ZBED3,RORB,POLA2,ZNF76,COPA,UQCR10,HMGXB3,ABCB10,COMMD5,MAP1LC3B,DST,RAB35,SIVA1,GPATCH1,DRAM2,DEAF1,SNRNP200,LAP3,NCK1,VHL,SREK1,ARHGDIB,PITPNB,HSPB11,BRWD1,PPM1G,SH3GLB2,CRCP,BAZ1B,CAB39,ACBD4,STK11,CLU,CHEK2,ZSWIM3,TSTD2,CHPT1,MRPL13,DCAF5,CAPN1,UBE2D3,NSMCE4A,PPP1R12A,ZCCHC8,GORASP1,UBXN1,NACA,RPL15,PCSK7,THRAP3,QSOX2,TTF1,PRPF18,CHKA,DTL,MED10,ZRANB1,MCPH1,SLC12A2,ATP6V0D1,CSNK1G3,CREG1,NUDT4,RPL6,VKORC1,SLTM,EVC2,KLHL15,SIAH2,SLC16A1,EHD4,SNRNP70,C11orf1,APOL2,N4BP2L2,SNX27,CHMP2A,CORO7,FEZ2,UCK2,PMS2,UCK1,CLCC1,EXT2,MXD1,USP5,HNRNPA2B1,SAP130,NVL,PPP6C,CYB5R1,ZNF770,EBAG9,RNF25,PCGF6,METTL2A,FAM72B,PON2,HNRNPR,HPS5,STAT6,MAPK1,BRD9,TMEM33,NAT14,DNAJC2,TRIP12,SHPRH,SCYL1,VPS45,GFM2,SPPL2A,FASTKD3,FGFR3,MZT2A,PPIG,ZDHHC13,TMEM99,H2AFY,NDUFS8,ATG13,ERI3,FBL,FRMD8,SLC35A1,MICAL3,TGFB1,B3GALT6,ELOVL5,HEMK1,TIMMDC1,HELB,PSPC1,MIER1,SCFD2,NDRG3,MTMR3,ACAT1,CENPT,PLOD3,RAB3IL1,RAB14,ADD1,KDM4A,MRPS15,XIAP,DHX8,GLUD1,ANKRD23,CDK5,CALM2,PSMD1,NEK6,NSRP1,RABGAP1L,SRSF4,FNIP2,KCNAB2,PCBP2,PLK3,ZNF672,MRPL43,HSDL1,TOPORS,MCL1,PPFIA3,SMC2,ICMT,SLC50A1,STOML2,LIMK1,ZNF689,PRDX5,ATE1,MLYCD,ST3GAL2,ATP6V0C,FBXL3,TFDP2,E2F2,PFKP,AAAS,DDX42,SSRP1,MRPL9,MRPS2,STRN4,TOP2B,ZNRF3,TMED3,DDRGK1,RAVER2,GNS,INTS7,INPP5A,MCM5,PHF14,ZNF326,NAGPA,TIMM8B,ETV3,TSPAN31,DHX29,TEX10,MAN1B1,RPS10,CBFA2T2,ABCF1,RHOB,LRRC14B,DTWD1,PTPRF,SCARB2,CCDC86,DUSP3,SLAIN1,MDH1,HEXA,RNF139,SNX14,ZNF296,TRERF1,UBR2,CHD1L,ACTR3,WDTC1,MYH9,CREBL2,NIPA2,PRKACA,SAFB2,STAM,ARL6IP6,RAB21,SP100,ZKSCAN1,DDA1,ANKRD13C,MAVS,CEP63,TMEM136,ATF2,RBM15,DCTN1,SHOC2,PSRC1,MAP4K4,WBP2,ATP6V0A1,DNAJA1,NDUFA7,TAZ,TAF2,SEC61A1,RPLP1,WDR7,CBLN2,RBMS1,FUS,GEN1,LRP8,COIL,LRCH1,GALK1,RPS2,SESTD1,TRAK1,JMJD6,SIKE1,AKT1S1,KRI1,FBXO3,ERH,GATC,PPP1R8,PRDM4,GTSE1,GEMIN6,DCP1A,SGCB,S100A6,IMPA2,NUDC,PDPK1,TK1,GUK1,TNFAIP3,GALC,ZNF512,KIAA0930,MRPS10,DDX39A,RPA1,ZNF862,ZNF180,KEAP1,POLE,TATDN2,PITX1,CAPN7,LRPPRC,PML,HMGB2,USF2,ANAPC4,SRM,DDX47,MCCC1,CDC42SE2,S1PR2,CDIPT,KCMF1,SSR1,LIN9,PCNA,ZNF639,TRMU,ETV6,PIK3R2,PPCDC,TXLNA,FAM86C1,MYBL1,MRPL32,CCAR1,ABCC5,PBXIP1,TLK1,MRPL12,EZR,LNX2,LRP5,BRCA1,PRKRA,STX16,EPB41,SEPT1,SOCS4,QRSL1,GLCCI1,NUDT11,GEMIN7,LZTR1,RACGAP1,PPP3CB,B4GALT4,RLF,RAPGEF6,SNRNP25,RB1,VASP,MED8,VMP1,PPIL2,MEA1,TIMELESS,AHDC1,ALDH18A1,TMEM8A,ABCC1,PREB,TRAPPC9,AACS,MEMO1,KRAS,RTF1,UBE4B,NFATC2IP,LY6E,ARPC1A,ZNF174,PSMC4,GOLGA4,SYNCRIP,PRPS2,NIPA1,TIGD2,RNF114,FOXM1,MRPL39,XAB2,DUSP22,COMMD8,RPL11,CSDE1,MDM2,CORO1A,METTL9,MINPP1,POC5,DVL2,GM2A,PSMA8,COQ10B,CPOX,TIGD5,SLC26A6,CYP20A1,PRPF3,TXNL4A,RPSA,SRSF1,DNAJC10,SCAP,ZNF700,PLEKHG4B,TIMM17A,FAU,LTA4H,AP2S1,USP53,CTDP1,MIF4GD,CDT1,ARID5A,SUMF1,GGA2,AP3S1,CSNK1A1,RMI1,TFRC,PTPN2,IRF4,STARD9,GSTK1,NDUFV1,SLC1A4,CWC27,SLC35B4,DDX31,ABCD1,RPAP3,CNTN5,SNX2,ZMYM5,CCDC34,CHCHD6,BSDC1,KPNA4,CDKN2AIPNL,FBXO41,BIRC5,TFE3,SNAP29,CDCA7L,PKD2,ACADM,CHMP7,SAT2,GCSH,ZNF496,TMEM109,TAP1,NHLRC3,IKBIP,EIF1B,ELMOD2,KIFC1,DBNDD1,RNASEK,CDC25B,PRADC1,DNMT1,NOL12,USO1,AKT2,NOL8,GNG7,AURKB,MCFD2,SLC25A5,ZFAND5,MAK16,STT3A,TMED10,PSMD8,EIF2D,ITGB1,PTPN7,UQCRH,RRS1,ARRB2,RTN3,SVIP,DDX58,WSB2,PPIB,MUT,GMFG,HLA-E,NDUFA4,MAN2B1,METTL3,CFLAR,NDUFS4,RNF121,MEX3C,KLF16,HDAC7,DAD1,BDH1,PCYT2,GNAI2,ANKHD1,TERF2,MORC3,KCTD20,SEPT8,DCTD,TOMM40,ADSS,SERTAD2,SERF2,ZFP92,NSF,DCK,ERGIC3,ACLY,LPCAT4,VCPIP1,YY1,PPP6R2,PPP6R3,MAP3K5,RNF14,CDK2,ZC3HAV1,SYS1,ZBTB37,URB2,EIF3D,MAGED1,KLHL18,ADPGK,SLC25A44,AP1B1,SDHA,PHC2,CRKL,TERF2IP,MOAP1,CYHR1,ZNF75D,SHC1,UCHL5,NAA35,TMBIM1,CCT2,CDKN2AIP,MKLN1,GALK2,CDC23,SHCBP1,AP4E1,PRDM11,VEZF1,PPP2R5A,ACYP1,STAT1,PPA2,TRIM32,RHEBL1,C1orf112,TCF3,MRI1,BRAP,AGPAT3,MYNN,SDF2L1,SPR,RAB11A,REEP5,FOXO3,MAD2L2,CCDC28A,PIP5K1C,RBM17,MAT2B,PTEN,CENPJ,TAGLN2,CREB1,SMC4,RNASEH2C,NEK7,NET1,PARP4,TBRG4,ANAPC2,RPL27A,YIF1A,SGSH,HGS,TTLL4,SLC38A7,MFAP1,CCDC69,BRWD3,ESYT2,SKA3,NPHP4,UBE2E2,HNRNPAB,PLXNC1,ST13,TMEM184B,DNAJC24,ZNF107,KIF2C,SLC29A1,AGFG1,SIRT2,FKBP2,USP48,SNRPD3,UBQLN2,CUTC,EDC3,UBLCP1,ZNF804A,RAP1A,THADA,EIF4A3,AP3S2,ATG3,DPYSL2,PPP1R12C,AKR1B1,NDUFB9,JOSD1,RP2,TTC4,TECR,ARID4A,FGFR1OP2,TIMM50,TDP1,DPM1,FOPNL,SLC16A7,WDR82,SLC25A22,STK17B,DHX15,CHAF1A,GEMIN5,COPS6,SASS6,RPS26,PSMC1,SLC12A7,TBC1D12,TM9SF4,ZNF768,UFC1,MED13L,TIA1,MEF2A,EPHX2,PITHD1,RHBDD1,NFATC3,BANF1,ZNF335,BUD31,YBX1,KNTC1,ACAD8,UBE3C,ZNF189,ALDH9A1,KDELR1,TSTA3,CIC,PSMA1,NAP1L1,EXOC4,KIAA1328,PITPNA,NAA20,PTDSS1,MZT2B,PDSS2,C7orf26,TMEM106C,IMMT,ASH1L,CHERP,WDYHV1,PLAGL2,CHKB,IRF3,TWF2,ANKRD28,FARSA,SAR1A,APOOL,PDIA6,ACSL5,TOR1AIP2,AZI2,GFER,RAD54B,TMEM41A,DAP3,ZNF317,GADD45B,AKNA,REEP4,CBX4,MIF,KIF3B,GOLPH3L,SH2D3A,CASP6,TOR3A,SRGN,DBF4,MFSD10,SAC3D1,CTNNBL1,YIF1B,CLDND1,TTC17,SLC25A1,GINS1,CSNK1G2,TELO2,ADAM17,HMGN1,NASP,ASPM,PRKAR1B,SYMPK,TARS,SNRPA,MAPK3,HSPA1B,HLA-B,ATAD2,PLAA,ZNF330,KBTBD7,PREPL |
| 6.018e-24 | -53.47 | FN1 (fibronectin 1) | protein interactions | 2335 | 769 | 234 | 17029 | 2761 |
SRM,DDX47,ST13,HNRNPAB,SNX15,CSNK2A1,USP39,GLUD1,KIF2C,SND1,SNRPD3,RBM4,PABPC4,RPL23A,PA2G4,NAPG,PCNA,NUP210,EIF4A3,RAB35,TTC9C,SRI,DNM2,AP2B1,EIF5,LRRC59,PCBP2,LARS,SNRNP200,SEPT9,VHL,SNRPB,LRBA,HNRNPF,EZR,PSMG1,ESYT1,MCM2,SLC25A5,DHX15,EIF3A,CLNS1A,EPB41,NECAP2,AHNAK,RPS27A,RPS14,MAP4,ITGB1,KPNA2,PRPF4,ACTB,MRPL13,RPS26,PFKP,CAPN1,FUBP1,RPS15,NDUFV2,MAPRE1,EWSR1,PHB2,NACA,SDC2,DHX9,TIA1,EPN1,RPL15,DNAJB1,NUP205,LMNA,RPN1,SUB1,VASP,MCM5,EFTUD2,RTCB,CAPZA1,CTR9,YBX1,RBM3,PABPC1,PPA1,EEF1D,FDFT1,EIF3L,NTPCR,SF3B6,RPS10,RPL6,GTPBP4,RPS24,PLEC,PKM,EIF4G2,EIF4H,ABCF1,CCT8,MATR3,PSMB3,XRCC5,RPL36,CAND1,EPRS,SYNCRIP,QARS,SNAP23,RBMX,PRPS2,ACLY,YWHAZ,ATP5F1A,RUVBL2,SNRNP70,RBBP4,HNRNPDL,ECPAS,PDLIM5,CDKN2A,NDUFA5,KARS,SARNP,RPLP2,NQO1,MDH2,SF3B1,EIF3D,ACTR3,COPE,RAC1,OLA1,MYH9,ATP6V1B2,PCBP1,GLRX3,STMN1,SDHA,RPL11,HNRNPA2B1,DECR1,PSMA6,IARS,SAR1A,TARDBP,CLTB,PDIA6,CFL1,PRPF19,CPNE1,CCT2,RPL29,RPL35,SEC61B,RAB7A,VDAC2,CIRBP,NUP155,GAR1,H2AFV,TRIM28,RPS9,RPSA,SRSF1,DDX17,AFDN,EIF3K,PPP2CA,DDOST,HNRNPR,RBL1,TAB2,CORO1C,FUS,FAU,SMAD4,TUBB,MIF,RPS2,RAE1,PDAP1,TKT,FLOT1,ATP5F1B,RAB11A,BZW2,TFRC,FERMT3,RPA2,GSTK1,GART,PDCD10,NDUFA2,RPL17,SEC24C,ARHGEF1,H2AFY,TAGLN2,CNN2,PTGES3,FBL,TTLL12,UBE2M,HNRNPM,SLC25A1,LDHB,TK1,PRKDC,TUFM,LDHA,RPL8,ILF3,RPL27A,MACF1,SYMPK,PICALM,TARS,SNRPA,SMAP2,PRDX1,HSPA1B,RPA1,CBX3,UPF1,PDCD6,PRDX3,HNRNPH3,LRPPRC,KHSRP,HMGB2,DDX5,SRSF3,YWHAH,IPO4,ESYT2 |
| 6.109e-24 | -53.45 | peptide transport | biological process | GO:0015833 | 1370 | 345 | 17256 | 2622 |
CCDC93,TMED7,RAB14,NUP188,PDCD6IP,TSC2,TAP1,AP3M2,SYNRG,RIC1,PARK7,RPL23A,CDK5,NAPG,SNUPN,RABGAP1L,RAB4A,SRSF4,AP1M1,DNM2,AP2B1,NUP153,SEH1L,SRP72,PGAP2,USO1,TMEM115,ATG9A,AKT2,MCL1,NUTF2,ICMT,MCFD2,RAB22A,RAB2B,ARF4,PLEKHF2,HHEX,SMAD2,TMED10,RPS27A,RPS14,EIF2D,VIPAS39,ATP6V0C,BTF3,RRS1,ARRB2,NMD3,ZMAT3,LONP2,AAAS,NXT2,GGA1,SEC61G,RAB23,ACAP1,TMED3,PSEN1,VPS25,COPG2,NPLOC4,COPB2,ATG4A,SNX18,FBXO7,TNPO3,ATP6V0A2,MVP,CPSF4,SYTL3,NUP85,TMED2,SRSF11,NAGPA,EIF5A,TIMM8B,GCC2,RPS10,RPS24,SSR2,SRSF5,MTX1,TOMM40,PTTG1IP,GOSR1,RHOB,DERL1,SEC31A,SCARB2,KPNA1,NSF,PPP3R1,SNX14,NUP58,EXOC3,ANKRD27,NDC1,SARNP,SYS1,RAB11B,RAF1,GPR89A,ANK3,VTI1A,C5orf30,MYH9,TBC1D13,AP1B1,STAM,RAB21,AHCTF1,TBC1D22A,TBC1D14,NUP107,TNPO2,TAP2,ZC3H3,ATP6V1G1,SNX8,SEC61B,GOPC,RNPS1,POLR2D,RPL38,SLBP,ATP6V0A1,RAB1A,AP4E1,ERC1,SERP1,PEX5,CHMP4A,HSPA4,SEC61A1,VPS26B,RAB24,RPLP1,SEL1L,PITRM1,RPS2,SCAMP3,SRSF6,TRAK1,BTN3A1,IFT27,RAB11A,JAKMIP1,RPL17,ARF5,RPL19,UPF2,MTX2,PPP3CA,GUK1,DENND1B,DENND4C,RPL8,RABIF,RAB3IP,DDX39A,MACF1,RPL27A,YIF1A,KIF18A,HGS,RPL32,LTBP4,STX18,PML,YWHAH,GPR89B,IPO4,VPS29,SNAPIN,POLA2,MTX3,COPA,THOC1,SNX15,RBM8A,ALKBH5,UBE2Q1,AGFG1,RUFY1,SEC16A,SSR1,RAB8A,NUP210,RAP1A,TIMM23,EIF4A3,AP3S2,RAB35,ATG3,PIK3R2,RP2,TIMM50,CDC37,VPS13B,FYTTD1,LARS,TLK1,RAB5B,STX16,LSG1,OPTN,NECAP2,RPL37,TRAM2,TBC1D17,TIMM13,EIF4ENIF1,HSPB11,GRIPAP1,UEVLD,TIMM29,MIA2,ARRDC1,KPNA2,VPS4A,CLU,RPS26,ATP6V0E1,C2CD5,RPS15,TBC1D12,GORASP1,PHB2,CENPF,RPL15,RAB6A,XPO7,RHBDD1,NUP205,RINL,KIF13B,ARL6IP1,GLE1,LRSAM1,ATP6V0D1,PREB,KDELR1,ABCC1,RPL6,SYVN1,ZDHHC3,NPIPA1,RPL36,TSC1,GOLGA4,SNAP23,EXOC4,ZDHHC7,SIL1,NUP62,CTSA,CHMP2A,SNX27,CORO7,TOMM20,RPLP2,COPE,ATP6V1B2,LYN,RPAIN,BCAP31,RPL11,HNRNPA2B1,ATP6V0B,ANKLE1,SAR1A,AKAP8,BCAP29,SCAMP4,AHCYL1,CLTB,CHTOP,LMAN1,CHP1,SNX25,RPL29,NXT1,RPL35,PPT1,RAB7A,NUP155,BICD2,ERBIN,CHMP2B,RPS9,RHBDF2,RPSA,SRSF1,SURF4,VPS26C,TOMM6,TIMM17A,ARNTL,AP1S1,CHMP4B,SMURF1,AP2S1,ABCA1,PARD3,CDC40,GOLPH3L,RAE1,NUP54,VPS45,ARFIP2,TIMM21,ARF1,GGA2,AP3S1,TFRC,KLHL20,SEC24C,RRBP1,ARHGEF2,STAT3,CAMK2G,MYO5A,TGFB1,ZDHHC18,NASP,SNX2,SCFD2,COG1,SYMPK,MFN2,RAB18,SEC23IP,UPF1,ATP6V1D,PDCD6,KPNA4,GOLGA7,SNAP29,RBPJ,SPCS3,SRSF3,ATP6V1C1,CHMP7,RAB3IL1 |
| 6.453e-24 | -53.40 | NPM1 (nucleophosmin 1) | protein interactions | 4869 | 590 | 193 | 17029 | 2761 |
DDX47,TXN,NOP2,CUL1,CSNK2A1,EBNA1BP2,SND1,BRIX1,MRPL19,PARK7,PABPC4,RPL23A,PA2G4,PSMD1,POP7,NOC2L,RPF2,ZNF800,FTSJ3,CDC37,NOL12,SRP72,PLK1,RPP25,NSUN2,MRPL12,MRPL43,MKI67,SREK1,BRCA1,MCM2,SLC25A5,MAK16,DHX15,EIF3A,DOT1L,RPL37,NIP7,RPS14,PPM1G,UQCRH,COPS6,RRS1,ARRB2,HDAC2,CCDC137,RPS15,EWSR1,TMUB1,HJURP,CENPF,KCTD17,RPL15,CTCF,SRRT,LMNA,LYAR,RB1,DDX56,VASP,EIF2S2,RBM34,ZNF746,RTCB,YBX1,AFF1,CPSF4,GNAI2,PPA1,EEF1D,ABCC1,NIPSNAP1,HP1BP3,GID8,EIF5A,EIF3L,DHX29,TEX10,RPS10,RPL6,GTPBP4,UTP15,USP10,RPS24,PKM,MPG,EIF4G2,PHF6,PSMC4,RPL36,CAND1,NAP1L1,KPNA1,CCDC86,GOLGA2,NUP62,YWHAZ,ATP5F1A,YY1,RBBP4,CDK2,CDKN2A,BCCIP,CYLD,MRPL39,COPE,SMARCA4,PCBP1,KTN1,APP,CHD1,RPL11,MRPL50,DECR1,MDM2,AHCTF1,SHC1,NVL,SIAH1,TARDBP,CFL1,CGGBP1,CCT2,RPL29,RPL35,CUL3,RPL38,DNAJA1,H2AFV,TRIM28,RPS9,EIF3G,RPSA,EIF3H,USP36,DHX57,SRSF1,SUPT16H,CHCHD3,NSA2,PPP2CA,HSPA4,SURF4,JAK1,HNRNPR,TAB2,STK38,RPLP1,H2AFX,FUS,FAU,PDCD11,CBX4,NIFK,RPS2,CDT1,MRPS26,NKRF,ARF1,NCAPG,PNO1,WWP2,RPA2,CTNNBL1,HUWE1,RPL17,MRPL54,DDX31,RPL19,NAP1L4,FBL,MRPL11,HNRNPM,STAU1,DDX24,ZNF512,WDR18,ABCF2,RPL8,TUFM,RCOR1,RPL27A,KIF11,CHCHD6,RPA1,KEAP1,RPL32,PML,COX8A,USF2,CD81,GPATCH4,BYSL |
| 8.355e-24 | -53.14 | cellular macromolecule biosynthetic process | biological process | GO:0034645 | 3671 | 757 | 17256 | 2622 |
ZBTB10,KDM4A,MRPS15,PIGQ,CCNL2,EDRF1,RBM4,ZNF275,PABPC4,EEF2K,RPL23A,USF1,CIPC,SRSF4,CRY2,ECD,ZNRD1,MGAT5,MRPL57,PGAP2,ZNF672,ZNF559,TMEM115,GABPA,MRPL43,WDHD1,MIER2,TOPORS,DIDO1,MCM2,GINS4,BRMS1,SMAD2,RPS27A,ZNF689,OGT,VIPAS39,ST3GAL2,TFDP2,SMAD1,E2F2,CHPF2,ZNF75A,SLC25A33,SSRP1,HIVEP3,MRPL9,CLSPN,MRPS2,DHX9,EZH1,CDC73,MCTS1,ATG4A,TFAP4,EIF2S2,INTS7,MCM5,EFTUD2,ZNF326,FOXN2,MRPL21,CPSF4,PABPC1,PHKG2,PPA1,CARS2,SRSF11,NAGPA,EIF3L,ETV3,FOXK1,RB1CC1,DHX29,ZMYND11,MAN1B1,RPS10,MYBL2,USP10,BCLAF1,MRPL16,SRSF5,CBFA2T2,ELK1,EIF4H,ABCF1,POLR2J,ETS2,SETD3,CNOT6,WIPI2,ZNF830,SGF29,MRPL3,ZNF296,KARS,SARNP,TRERF1,IVNS1ABP,PTTG1,RMI2,CREBL2,RXYLT1,ZNF267,INO80E,EFL1,SAFB2,RCOR3,TCF19,ZNF420,SP100,ZKSCAN1,MTA1,DUT,GMEB1,NABP1,INTS12,ZNF226,ATF2,RPRD1B,CGGBP1,CPNE1,POLR2L,EID1,KAT7,INTS13,WBP2,RPL38,POLR2D,RNPS1,E2F3,NDUFA7,MEF2D,DDX17,TAF2,CHCHD3,HIPK2,RPLP1,RBMS1,SNRPG,PPP5C,ZBTB11,COMMD10,ZNF786,RPS2,ZNF445,SRSF6,HABP4,TRAK1,JMJD6,WDR5,ETS1,NEXMIF,ZNF92,RPA2,ZBTB45,GATC,SUV39H2,PPP1R8,PRDM4,ZNF260,LTN1,ST8SIA2,ZNF710,GTF2H2,RPL22L1,MED22,PDPK1,TK1,POLK,ZNF512,MRPS10,DDX39A,RPA1,ZNF180,ZNF862,KEAP1,MAGT1,POLE,PITX1,DBI,LRPPRC,PML,HMGB2,USF2,WDR45B,THAP5,THOC1,GPBP1L1,RBM8A,CSNK2A1,SND1,BIRC2,PAPOLA,CREM,LIN9,TET3,PCNA,GLIS2,ZNF639,INTS1,ETV6,XRCC2,NOC2L,EIF5,MCMBP,MYBL1,MRPL32,CCAR1,RYBP,SP3,HARS,BAZ2A,RAD51AP1,SNRPB,MRPL12,CDC6,PBRM1,EAF2,BRCA1,KRTCAP2,USP21,ALG3,TONSL,CHD3,ZNF367,E2F4,QRSL1,DVL1,ZNF45,BEND6,FAM208A,POT1,ZNF564,FUBP1,ZCCHC9,PHB2,CENPF,CTCF,CHCHD2,CDK13,B4GALT4,RLF,ASXL2,CNOT11,ARID1B,C1GALT1,SUB1,RB1,MLX,NUS1,MED8,MBD2,SSBP3,ZNF746,CTR9,TIMELESS,MDFIC,ICE2,MRPL48,MAML1,PREB,LDB1,UTP15,RTF1,ZNF761,LY6E,EIF4G2,ZDHHC3,NMT2,IRF5,ZNF174,RXRB,RPL36,GALNT2,PALB2,TBPL1,ZDHHC7,PRMT7,DTD1,RUVBL2,CYLD,TRAF7,RPLP2,UGP2,ARID2,FOXM1,MRPL39,DYNLL1,XAB2,ZNF416,RRAGC,COMMD8,ZNF121,RPAIN,RPL11,MRPL50,NRF1,ZBTB21,ZNF473,KMT5C,ZNF302,MRPL34,RPAP1,TARDBP,LMAN1,TOP1MT,SAP30L,ZNF583,DVL2,KDM3B,RPL29,RPL35,POLR2G,ZNF780B,BTG2,NFATC2,KDM1B,MRPS14,EIF3H,RPSA,SRSF1,MRPL2,ZNF700,RBL1,MAFK,ZNF436,DNAJC17,XRCC3,NCOA1,SMAD4,RAD51D,INTS2,SLC30A9,CTDP1,NIFK,MCM10,CDC40,MTERF1,CDT1,AGO2,ARID5A,GTF3A,NKRF,PAGR1,RMI1,WRNIP1,IRF4,SS18L1,PTGES3,POLR1B,ORC3,RBM15B,CNTN5,RPRD1A,HMGN5,ZNF202,ZMYM5,TUFM,TOP3A,PCGF1,GOLGA7,BIRC5,L3MBTL3,TFE3,CDCA7L,BBX,E2F1,RBPJ,TAF12,NR2F2,HIPK3,IFI16,TXN,ZNF496,MAX,GXYLT1,ZDHHC8,CXXC1,GYG1,CCNB1,EIF1B,COMMD6,POLR3K,MYEF2,PA2G4,NOL11,FIZ1,ZNF200,TAF5L,DNMT1,ZNF800,CDC5L,ZNF524,KLF10,AKT2,ELOA,GALNT7,USP22,MCFD2,CBFB,RFC2,EIF3A,PRIM1,IWS1,HHEX,BRD2,STT3A,RPS14,MRPL27,EIF2D,BTF3,ARRB2,ZNF598,CCDC59,HDAC2,B4GALT2,PTOV1,EWSR1,DHPS,POLR2K,CHTF18,PRKAA1,GSPT2,RRM1,B4GALT1,NOTCH2,PMF1,SUPT7L,PSEN1,TMEM165,ZNF518A,ZNF79,VPS25,NPLOC4,CNOT3,YY1AP1,RPN1,LHX8,KLF16,HDAC7,DAD1,PIGG,MRPL40,EEF1D,TERF2,EIF5A,PHF10,ZNF84,PIGT,PRIM2,ELL2,NOA1,ZNF574,MFNG,RPS24,ARID1A,KDM3A,TWISTNB,PHF6,XRCC5,EPRS,ZNF777,SERTAD2,GOLGA2,ZFP92,RBMX,QARS,MED15,CEBPG,PIAS2,YY1,RNF14,CDK2,NRBP1,ZNF511,ATXN3,RWDD1,ZBTB37,SUZ12,EIF3D,SDE2,TERF2IP,SPINDOC,ZNF75D,KDM2A,UCHL5,LPIN2,MRPS27,RNASEH2A,CDK12,SAP30,BRD4,RFC3,ERF,DRAP1,SLBP,ELP4,EDF1,POLG2,GAR1,TRIM28,SERP1,CENPU,PRDM11,SUPT16H,EIF3K,VEZF1,RAD51C,ZNF282,DDOST,MRPL55,HINT1,SAFB,STAT1,FTSJ1,PPA2,ATF6,BEND3,B4GALT3,EYA2,ATMIN,POLQ,POU3F2,NCOR2,DEPDC1,TWNK,MECP2,B4GALT5,TCF3,SECISBP2,MYNN,ARGLU1,SDF2L1,BLM,POFUT1,FOXO3,HMG20A,MAD2L2,WWP2,GTF2F1,CCNK,RFWD3,RPL17,ELP5,FUT8,MRPL54,RPL19,CARF,CITED2,CREB1,OSTC,CNOT6L,NCOA2,TSHZ1,ZFP64,KAT2A,WDR18,ILF3,RPL8,RFXANK,RPL27A,COMMD4,KLF6,GUF1,POLR2A,CBX3,RPL32,ZHX1,TFDP1,KHSRP,DDX5,TAF6,CPEB2,PURA,RORB,CCNC,POLA2,ZNF76,PTMS,IER2,PIGM,KMT2E,PHRF1,MOGS,ZNF107,SIRT2,TAF6L,SNRPD3,COMMD5,MAPK14,SNAPC4,MRPL19,ZNF696,EIF4A3,JAZF1,PHTF1,ZBTB22,TCEA1,SLC35C2,ARID4A,CARM1,ELOF1,LARS,DEAF1,DPM1,RIOX2,RRM2,SOX4,KMT2C,ASF1B,CHAF1A,RPL37,MAN2A2,GEMIN5,UBTF,PAF1,BRWD1,IARS2,PQBP1,CRCP,BAZ1B,ZNF268,CHEK2,GALNT10,MRPL13,RPS26,RPS15,PIGN,GORASP1,ZNF768,NACA,MED13L,RPL15,MEF2A,THRAP3,SRRT,TTF1,LYAR,DTL,NFATC3,ZNF449,MED10,PYURF,BUD31,ZNF335,YBX1,ACAD8,ZNF189,VOPP1,POLR2I,CIC,RPL6,SYVN1,EIF2A,SLTM,DAPK3,ISG15,NAP1L1,NFIL3,NUP62,ZFP90,RBBP4,HNRNPDL,ADNP2,ZBTB24,TCF12,MBD1,ASH1L,MPHOSPH8,SMARCA4,PLAGL2,NSD3,IRF3,ORC1,EXT2,CHD1,MXD1,PAIP1,MEAF6,SAP130,FARSA,RRN3,IARS,CD3EAP,AKAP8,RPN2,CHTOP,UTP4,ZNF770,RLIM,CSTF1,POU2AF1,ZNF500,PCGF6,ATXN1,MBD3,EIF3G,RPS9,ZNF317,DAP3,STAT6,CHCHD1,ARNTL,CANT1,AKNA,MAPK1,BRD9,ABCA1,CBX4,PDF,NAT14,DNAJC2,MRPL42,ZNF316,EYA1,SCYL1,MRPS26,DBF4,KLF13,PAWR,MXD4,GFM2,MAN1A1,KMT5A,PELO,RRBP1,NABP2,ANP32A,BRD7,MRPL11,STAT3,SAMD4B,B3GALT6,GINS1,ZDHHC18,GTF3C6,NASP,PSPC1,HELB,MIER1,POLR3GL,RCOR1,MEN1,ZNF407,SYMPK,TARS,MAPK3,TFEB,CNOT9,UPF1,ATAD2,KMT2B,SRSF3,PLOD3,ZMIZ1,TERF1 |
| 9.086e-24 | -53.06 | MORF_HDAC2 | MSigDB lists | MORF_HDAC2 | 265 | 107 | 17377 | 2626 |
KARS,IMMT,H2AFZ,NUP188,HNRNPAB,CHERP,ACTR3,STARD7,CUL1,SDHA,PABPC4,RAD23A,HNRNPA2B1,IARS,GOT2,MTA1,DUT,TXLNA,MRPS27,CS,HADHB,TARDBP,TCEA1,DNMT1,CCT2,SNRNP200,AATF,HMGN4,PPT1,VDAC2,SLBP,DNAJC9,MCFD2,MCM2,VDAC1,TXNL4A,SERP1,CLNS1A,CHAF1A,SRSF1,KRIT1,PPP2CA,HNRNPR,SAFB,PPM1G,BAZ1B,SMNDC1,HDAC2,SSRP1,MRPL9,TM9SF4,RRM1,CYCS,XPO7,AP3S1,CNOT3,HDDC2,TFAP4,RPA2,RPN1,NDUFV1,DNAJC8,EIF2S2,SEC24C,AHSA1,MSH2,EI24,CAPZA1,TNPO3,ANP32A,PTGES3,MTX2,HNRNPM,NUDC,IFRD1,POLR2I,MLEC,NSDHL,PRKDC,ILF3,TUFM,DCTD,BMS1,DDX39A,EIF4H,ABCF1,CDK11A,MAP2K2,SNRPA,TARS,POLR2A,RPA1,XRCC5,SDHB,EPRS,PRDX3,MFAP1,RBMX,PRPS2,TFDP1,LRPPRC,KHSRP,NUP62,MDH1,RUVBL2,CDK2,PTDSS1 |
| 1.146e-23 | -52.82 | large_cell | COSMIC cancer mutations | large_cell | 15281 | 2417 | 17385 | 2587 |
HECA,ZBTB10,ABCC10,HEXB,CCNL2,FBXO22,EEF2K,RAD23B,ATP13A3,DNM2,ZNRD1,FTSJ3,USP34,CCDC57,ERCC1,NRAS,EHMT1,KIF15,HNRNPF,WDHD1,MIER2,DIDO1,MCM2,RAB22A,SMAD2,MID1IP1,RPS27A,MPV17,COX5A,SMAD1,ZNF75A,ANXA11,SLC25A33,SEC61G,GGA1,MUM1,CCZ1,TRIO,CUTA,RAB23,KCTD17,HAUS4,EIF2AK4,APH1B,PARN,CDC73,MYL6B,ATG4A,TMEM179B,PDXP,SMC3,MVP,NSUN4,PPA1,IFRD1,AGGF1,FOXK1,RBM42,GTPBP4,MAP7D1,MRPL16,ELK1,EIF4H,RDH11,MAGED2,KPNA1,ETS2,TYW5,WIPI2,RUFY3,PDLIM5,ACSF2,EXOC3,RHOG,STARD7,VTI1A,C5orf30,INO80E,SLC35B2,LCLAT1,RCOR3,CPNE3,KIAA1147,RBM23,ZNF420,AHCTF1,TBC1D22A,TBC1D14,GMEB1,NSFL1C,SEPT11,GPD1L,ZC3H3,ARL5A,PDCL3,SNX8,ERMP1,EID1,IDH3A,POLR2D,HTATIP2,MEF2D,TMEM147,GSTCD,TANC1,MAT2A,VPS26B,NSMCE2,CORO1C,CAMKMT,PPP5C,PITRM1,TUBB,COMMD10,ZNF445,SRSF6,HABP4,CCM2,FLOT1,BTN3A1,ATG2B,ABHD14B,PPP1R3B,GOLM1,ZBTB45,HUWE1,ZNF260,NAA50,ANXA5,LTN1,UBE3B,NAP1L4,ZNF710,ST8SIA2,MED22,SPTAN1,STAU1,DDX24,TCTEX1D2,TACC1,MRS2,LDHA,HEBP2,LLPH,RAB3IP,TTC33,PICALM,SH3BP5,SLC19A1,ACOX1,FAM3C,AEN,PARP10,YWHAH,GPATCH4,FAM129A,TRIM11,YTHDC2,SNX15,RBM8A,ENSA,NENF,SND1,RUFY1,TRIM65,ZER1,PRNP,KRR1,RAB8A,NT5DC1,NOC2L,EIF5,TACC3,VPS13B,PTPN18,MIOS,SNRPB,MBLAC2,CDC6,UTP3,USP21,TRAM2,FBXO28,BCL7C,ARRDC1,ADAM9,DVL1,ZNF564,FUBP1,C1orf74,CTU2,PARP12,ZCCHC9,CENPF,LAMTOR3,CHCHD2,NCKAP1,LYRM2,RSAD1,TNS3,SUB1,RINL,SSBP3,MBD2,XPA,AHCY,RBM3,GLE1,LRSAM1,HDHD2,NTPCR,NSDHL,AMD1,CAMSAP1,ZNF761,METTL22,ICAM2,STYXL1,APPL1,BBS12,ANKRD46,RXRB,SDHB,PCM1,GALNT2,TMEM168,NLRC5,RUVBL2,BTBD10,MYO9A,CCNB2,USP7,GLT8D1,RPLP2,SUCLG1,ARID2,TMX4,SLC2A1,ATP6V1B2,PCBP1,LYN,BCAP31,VAV1,TMEM69,MRPL50,PSMA6,ZNF473,BRPF3,TARDBP,BCAP29,CTDSP2,PRPF19,PPIF,KDM3B,MND1,CLCN3,BIRC3,RAB7A,ANKRD33B,PPIE,CHMP2B,VDAC1,EIF3H,TMEM201,GLOD4,IDE,DHX16,UHRF2,CHMP4B,XRCC3,PARD3,BCL2L12,C19orf53,MCM10,KLHL21,PDAP1,TMX3,CDCA8,ARF1,SLC12A9,TUBGCP2,DNAJB9,HOMER1,POLR1B,RNF5,RBM15B,PPAN,RHOA,RPRD1A,BTAF1,TOP3A,ARHGEF12,PCGF1,DDX23,RAB18,CACNB1,PDCD6,ATP6V1D,L3MBTL3,FAM110A,NEIL3,CTBS,BBX,IMPDH1,TAF12,NR2F2,PGAM1,HIPK3,IFI16,TXN,H2AFZ,PNISR,TMEM203,PRKCSH,USP39,UBE2I,PARK7,SLC25A37,ASPHD2,ZNF428,RAB4A,TRA2B,SUCLG2,TAF5L,CISD2,SMARCE1,ZNF800,CDC5L,ZNF524,SGCE,OSBP2,NSUN2,USP22,CLNS1A,EIF3A,ZMYM3,DOT1L,IWS1,ANKRD10,WAS,KIF18B,TPP2,C1orf109,ZMAT3,B4GALT2,PRPF38B,RECQL,C9orf78,EWSR1,GADD45G,RRM1,ACAP1,B4GALT1,CYCS,FAM136A,SUPT7L,TMEM165,NPLOC4,CNOT3,SPAG5,WDR48,RTKN,CEP104,EXOSC7,KLHL5,LRRC8D,PPP4R1,MSH2,PIGG,FBXL7,MRPL40,SYTL3,FAM171A1,APOL1,EIF5A,GCC2,PRIM2,ELL2,RDH10,MFNG,RPS24,GORASP2,CAPZA2,ADRB2,CCT8,MTR,PHF6,PFDN5,SLCO4A1,TTC13,GOLGA2,RBMX,MED15,PIAS2,APPL2,SAMD8,NUDT3,CDKN2A,ZNF511,ATXN3,RAF1,KIAA0232,C2orf49,CD320,EPM2A,CCNA2,MTMR4,BRI3,TP53BP2,AQR,RBM12B,ILKAP,CDK12,SAP30,BRD4,DRAP1,NARF,LRRC8A,ELP4,ABHD11,PKMYT1,ASB13,SERP1,TRIM28,SUPT16H,EIF3K,CHMP4A,CBWD1,ATF6,XRCC4,PRPF4B,ADAM23,NDUFS1,DEPDC1,MECP2,SECISBP2,HMG20A,WWP2,JAKMIP1,SLC25A36,DNAJC8,AXIN2,CITED2,JMJD4,ANKRD37,KAT2A,TMEM126B,RABIF,ADSL,BMS1,KCNQ1,ARSK,MACF1,KIF11,COMMD4,KLF6,SMAP2,FADD,SH3GLB1,MYO1F,CBX3,TMEM127,INF2,PPP1R11,DUSP11,DDX5,WDR62,TAF6,ESPL1,PURA,DDB1,DEF6,IPO4,FAM83G,UBL3,NAT9,PIGM,LYRM4,GPR132,UBE2Q1,PTP4A3,BRIX1,MRPL19,ZNF696,SF3B2,PCYOX1L,CDC42,SYNM,GOT2,JAZF1,HADHB,RPF2,SLC35C2,CNNM3,CARM1,SRPK2,WDR41,LARS,ZCCHC10,CCDC138,LRBA,SUMF2,KMT2C,PRPSAP1,ASF1B,RPL37,MAN2A2,EIF4ENIF1,NIP7,U2SURP,MIA2,ZNF268,ATP6V0E1,PPP1R2,PM20D2,XPNPEP3,RGS2,LYAR,FAM89B,POLR2I,TRAFD1,SUGP2,GBA,SYVN1,DAPK3,ARHGAP15,MASTL,UAP1,NFIL3,FN3KRP,YWHAZ,CTSA,TMEM14A,TOB1,TSEN15,ADNP2,TCF12,PRKAB1,MDH2,SMARCA4,RRN3,UBXN2A,IARS,CD3EAP,KIF14,EXOSC1,CS,CLTB,DNAL4,CSTF1,POU2AF1,UBQLN4,HPDL,PGGT1B,SELPLG,SMU1,ATXN1,GLO1,OGDH,BICD2,CADM1,EDEM2,HERPUD2,TOLLIP,FANCE,MBD3,PDHX,RPS9,ALKBH6,SURF4,DUS3L,ARNTL,ANP32E,FKBP5,TMEM101,CCDC125,ABCA1,PDCD2L,GCLM,RAE1,DCTN2,CHIC2,PAWR,MXD4,DCUN1D4,PIP4K2A,XPR1,FERMT3,KIF5B,KLHL20,SEC24C,RRBP1,ARHGEF2,LDLRAD3,STAT3,MYO5A,NIPAL3,AMPD2,TXNL1,PHF20L1,DCAF6,FAM49B,TMEM39A,ATP2C1,RFFL,COG1,RCOR1,PRMT2,TFEB,LEMD2,UPF1,ELMO1,ZC3H7B,DTX4,ZMIZ1,TERF1,HRAS,CCDC93,FGFR1OP,TMED7,PIGQ,AGPAT1,CNTROB,PPP1R16B,MIS12,GSDMB,TTC9C,PDS5B,SENP1,PGAP2,TMEM115,PLEKHM3,DCUN1D5,PLEKHF2,BRMS1,PWWP2B,TRIM47,WDR11,AXIN1,SMG9,TRIM52,LONP2,NDUFV2,PHF23,CERK,SLC4A2,EZH1,ITGB5,LMNA,FBRS,MCTS1,DDX56,EIF2S2,SLC38A5,FOXN2,CARS2,PRRC2A,C16orf72,RB1CC1,ZMYND11,PGS1,MYBL2,UHRF1BP1,SRSF5,MPG,MATR3,CYB5A,NCDN,POLR2J,SETD3,PTAR1,CNOT6,NDE1,EGLN1,ZNF207,ANKRD27,ABCA3,SARNP,IVNS1ABP,MON1B,RMI2,TMEM97,NIT2,NUF2,ZNF267,TCF19,TMEM161B,KTN1,APP,PRKD3,CLUAP1,ATP2A2,UTP18,DUT,ANAPC7,RNF19A,FAM76B,CLN6,TMEM9,GCC1,RNF169,ADCY7,ATP6V1G1,ENPP4,RNPS1,CDCA2,FKBP3,GPR137,DDX17,CHCHD3,PEX5,CDC16,HIPK2,MBOAT1,TICAM1,PDXK,ZBTB11,TMBIM4,GMCL1,UBE4A,IL21R,ETS1,WRB,ZNF92,PNO1,CAPN2,ADD3,SUV39H2,TTLL12,TPCN1,TMX1,LYPLA2,HNRNPM,LDHB,PPP3CA,NUDT8,POLK,JTB,EMP3,MTMR12,ZP3,PDE3B,KIF18A,CCDC6,WNT5B,MAPK6,C4orf46,LY75,SLC25A19,RGL1,PSAP,WDR76,IGBP1,FAF1,SNAPIN,COX15,AGRN,THOC1,GNPDA1,GPBP1L1,PPP1R15B,CSNK2A1,EBNA1BP2,GIT2,BIRC2,ATPAF1,DLG5,ABL2,XRCC2,ZFYVE27,MCMBP,PTPRK,CDC37,SP3,METTL1,EXOSC6,HARS,GMFB,ESYT1,ANLN,RAB5B,RHEB,DPYSL3,TBC1D17,TIMM13,CDCA4,TONSL,NRM,NAGLU,ACTB,ZNF45,TMUB1,CTCF,ASAH1,DOCK11,CRLF3,ASXL2,LRRC14,SLC27A4,AFF1,MDFIC,MAML1,CYTH1,NQO2,UTP15,EIF2AK1,EIF4G2,ZDHHC3,MOSPD3,ITPRIPL1,CDC27,SNAP23,TBPL1,PRMT7,KCTD7,NDUFA5,CYLD,UGP2,DYNLL1,COPE,HCFC1R1,ZADH2,GGPS1,RPAIN,RAD23A,SEC11A,ATP6V0B,PDK2,STRBP,TNFAIP8,DUS4L,MRPL34,PDCD2,SAP30L,SLC39A9,CLPTM1,RPL29,RPL35,BTG2,DNAJC9,MTMR6,FRAT2,NFATC2,KDM1B,ARL5B,USP36,CCDC127,MRPL2,ATP1A1,CLK3,PSMD3,MAFK,CEP55,NDUFA11,DNAJC17,ZNF436,NCOA1,SLC25A39,ZC3HC1,ZNF146,ATXN7L2,CDC40,GOLIM4,SMAP1,RRP15,DAP,GNE,SMC6,ARFIP2,NKRF,CHAC2,BZW2,WRNIP1,SS18L1,CENPM,PTGES3,CAMK2G,MLEC,ZNF202,PPWD1,FAM50B,RHOT2,NEU1,TPD52L2,GOLGA7,TWSG1,PGRMC1,GLG1,FAM126A,SPCS3,RPS6KC1,UBE2C,PPCS,NDUFB6,TMEM41B,ZDHHC8,PLXNA1,CCNB1,SLC20A1,COMMD6,ABHD14A,POLR3K,C14orf119,ASAP2,SNUPN,CNPY4,PLCL2,TFG,SEH1L,ATG9A,PBK,MKI67,DDX20,AMDHD2,GALNT7,SLC17A5,CCNF,FOXRED1,RBM47,PTER,WDR4,DHTKD1,TRAF5,HDAC2,PWWP2A,HSPH1,LIME1,MAPRE1,CHTF18,ADO,KIF23,SLC35B1,NOTCH2,PMF1,JMY,FKBP1A,SLC31A1,SNX18,ATIC,ATP6V0A2,PIKFYVE,RNF135,LPCAT1,EEF1D,TMED2,FTL,PHF10,DDX28,ZNF84,SIGMAR1,PIP4K2C,RIT1,PLEC,KDM3A,SF3A2,FAS,EPRS,ZNF777,TMEM54,QARS,PPP3R1,TCOF1,CABLES1,NRBP1,DNMT3A,RWDD1,CKLF,TRIP10,SF3B1,CAST,SUZ12,RAC1,GPR89A,GNB2,FLAD1,APLP2,KDM2A,CDKN1B,TNPO2,TALDO1,GPX4,ATP13A1,RFC3,MAPRE2,ERF,CUL3,SLBP,KIAA1586,H2AFV,POLG2,GAR1,PSMB9,DHX57,NSA2,HSPA4,MRPL55,JAK1,TBL3,SEL1L,H2AFX,KLHDC4,B4GALT3,PDCD11,ATMIN,POLQ,POU3F2,NCOR2,ANKRD13D,PKP4,SCAMP3,CDCA3,SLC25A12,BLM,TMCC3,GTF2F1,CRAT,AHSA1,PRC1,UPF2,COPS7B,SLC38A10,CNPY3,UBE2M,IFT46,TMEM160,TSHZ1,ZFP64,DENND4C,DENND1B,WDR18,RPL8,ILF3,LRRC1,RHOT1,TSR2,MARK2,ECH1,PRDX1,PLD3,NUCB1,FBXO21,GNA12,C1orf131,PRDX3,PFDN4,HNRNPH3,STX18,TFDP1,KHSRP,ASNA1,CPEB2,SSSCA1,BYSL,VPS29,S100PBP,MIB2,IER2,PTMS,NOP2,UBN1,NF1,DCAF15,FLYWCH2,ALKBH5,MOGS,TAF6L,MAPK14,BECN1,SNAPC4,RNF103,BCAT2,MBD4,C18orf32,METTL14,ZNHIT6,IMPAD1,RCSD1,PHTF1,SRI,KIF22,ZBTB22,NFU1,TRIM14,ELOF1,COPS8,FYTTD1,TRIM8,RRM2,SOX4,ABHD5,CXXC4,UBTF,UEVLD,SPATA2,PQBP1,IARS2,ATXN2L,GALNT10,STARD3NL,RPS15,PIGN,AGTRAP,CIB1,XPO7,SRRT,ZNF449,CAPZA1,GLTP,KIFAP3,BCL2,N4BP2,HP1BP3,THNSL1,ISG15,CAND1,GNAS,TSC1,RBM25,CDCA5,ZFP90,NANP,RBBP4,ZBTB24,SMARCD1,MBD1,WASF2,MMACHC,TOMM20,IFI27L1,GNPNAT1,MPHOSPH8,HNRNPUL2,CHD1,MEAF6,C2orf68,CCDC50,AKAP8,PARL,RPN2,CHTOP,FAM3A,F2R,SCYL3,TMEM14C,ABI1,HTRA2,MOSPD1,RLIM,FAM172A,ZNF500,PSMB7,NLN,WIPF1,BUD13,NDUFB1,PEF1,EIF3G,BTBD1,TAB2,CHCHD1,TULP3,WDR59,CANT1,SCARB1,GAS2,USP11,SMURF1,PPP2R2D,TSPAN5,CDS2,MAGEH1,MRPL42,EYA1,CDK2AP2,MRPS26,LETMD1,KLF13,HDDC2,RGS1,MAN1A1,FBXO5,GART,PELO,TANK,BRD7,MRPL11,SAMD4B,ZDHHC18,GTF3C6,POLR3GL,WDR81,MEN1,ZNF407,MFN2,COX8A,ZRANB2,SRSF3,MBD6,ATP6V1C1,IDH3B,TATDN1,TSC2,LACTB2,CMTM6,RBM4,ZNF275,ANKRD39,RPL23A,CDKN2C,USF1,MECR,AP1M1,UPRT,CRY2,ECD,RNF26,TIPARP,LRRC59,ANKRD9,RHBDD2,MGAT5,BAK1,ZNF559,RHOBTB3,GABPA,WBP1,ARF4,GINS4,KRIT1,BOLA3,AHNAK,RAD18,PDRG1,RNASEL,CHPF2,SMNDC1,PDCD4,HIVEP3,KIAA0100,CLSPN,RHOC,DHX9,PDCD7,PSMD9,HAUS2,COPB2,CD59,TFAP4,RNFT1,MEGF8,RIMS3,EFTUD2,FBXO7,CPSF4,MRPL21,PHKG2,LUC7L2,SRSF11,EIF3L,MTA2,TYW1,ITM2A,SSR2,BCLAF1,MTX1,SFXN5,FNTA,PDLIM1,TXNDC16,ZNF830,TMEM159,MRPL3,ALS2,FAM72A,TRIM41,KARS,NQO1,POC1A,ANK3,PTTG1,TPX2,TBC1D13,DAZAP2,GLRX3,STMN1,REPS1,ABHD16A,FBXL6,SH3BP1,MTA1,UBA5,CLCN6,INTS12,C8orf59,RPRD1B,CGGBP1,CPNE1,SEC61B,POLR2L,FAM118B,GOPC,E2F3,CIRBP,RPL38,CRNKL1,PFKFB3,GORAB,RAB1A,GIGYF1,TMEM184C,PPP2CA,KIF2A,CCDC14,LSM6,RNF38,SNRPG,DMWD,USP13,MZT1,ZFP91,TRMT6,IP6K2,WDR5,SLC25A43,IFT27,PMVK,NEIL2,RRP36,SRXN1,RPA2,PSMD2,CLIC4,PDCD10,CBWD2,COQ4,ITGB8,ARF5,ARHGEF1,FBXL19,GTF2H2,TTPAL,UTP20,MAGT1,GPS2,DBI,SSNA1,MRFAP1L1,CD81,TMEM131,WDR13,FANCI,CREM,FANCL,GLIS2,IL6ST,POP7,SLC44A1,MTPN,ASB6,PLK1,RPP25,CELSR2,SEPT9,RBX1,APH1A,RAD51AP1,CKAP2L,PSMG1,UBE2V1,EAF2,IL12RB1,KRTCAP2,LUC7L,LSG1,NECAP2,C1orf122,TRIM4,AGPAT2,CHD3,ZNF367,E2F4,PRPF4,BEND6,CLN3,DNAJC30,NGLY1,POT1,MYL12B,CCDC137,RMND5A,HJURP,PHB2,DNAJB2,FAM53C,NKD2,SDC2,KLC1,CDK13,ADCK5,COX4I1,DNAJB1,RAB6A,ARID1B,C1GALT1,MLX,UBE2Q2,CCP110,ZNF746,ARL6IP1,CTR9,NIPSNAP1,ABHD2,DCAF8,ACSL3,LDB1,MAP4K3,ARMC8,NMT2,IRF5,RPL36,HAUS8,MBIP,COX7A2L,ZDHHC7,SIL1,FAM122A,DTD1,UNC13C,BCCIP,SART1,TRAF7,NDUFAF2,TOR1AIP1,ZNF416,LAGE3,ZFYVE21,TM9SF3,RRAGC,ZNF121,NRF1,WDR44,PIN1,EFCAB11,RPAP1,CABLES2,LMAN1,AHCYL1,TOP1MT,STRAP,SPSB3,ZNF583,SNX25,ARHGAP17,POLR2G,ZNF780B,PPT1,DCLRE1C,MRPS14,RHBDF2,SUGP1,RBL1,FASTK,UBXN2B,STK38,AP1S1,SPRYD4,SLC22A23,H3F3A,CHID1,SMAD4,RAD51D,SLC30A9,CMAS,UNK,NADSYN1,HMGN3,NCAPG,SCYL2,FZD6,HERC3,GTPBP3,CTSS,RNLS,YTHDC1,ACP2,HMGN5,CSRP1,METTL5,ABCF2,TUFM,RANGAP1,PNPLA8,HAGH,API5,ZFR,SEC23IP,E2F1,TMEM219,USP20,RBPJ,PDCD6IP,MAX,LUZP1,GXYLT1,ADAM10,CXXC1,TSC22D3,AP3M2,CUL1,GYG1,NANS,MYEF2,ANKRD26,NOL11,FIZ1,ZNF200,MARCH2,SLC26A2,SRP72,KLF10,LACTB,RFC2,CBFB,RAB2B,MAP3K4,HHEX,LUC7L3,RPS14,MAP4,MRPL27,BTF3,PTPDC1,NMD3,CCDC59,PTOV1,COX5B,DNAJC5,SCOC,DHPS,POLR2K,ANKH,C16orf87,VAV2,GSPT2,TATDN3,DLGAP4,PXMP2,PRPF39,PSEN1,ZNF79,PDXDC1,VPS25,NDUFS7,YY1AP1,C12orf10,FAM192A,RPN1,LHX8,ARPC5,ZNRF2,TPST1,DAPK1,PIK3IP1,CYC1,SOCS5,FDFT1,PIGT,EMB,WDR1,ZNF574,C1orf35,EXOSC9,ARID1A,PTTG1IP,C9orf40,FXR1,GOSR1,TWISTNB,AKAP1,XRCC5,HMGN2,PI4K2A,CAT,DERL1,HSPBP1,MTHFD2,ARAP1,USP32,FAM83D,CABIN1,SMPD4,GPI,CYTIP,TP53RK,REPS2,RAB11B,UROD,SLC39A13,POMP,BCL2L1,NUDT19,DECR1,RALB,SIAH1,ADCY9,LPIN2,MRPS27,SOCS6,TTC3,RNASEH2A,CFL1,ANKLE2,CDC123,VDAC2,EDF1,EML4,ERC1,AMZ2,ANKZF1,ZNF282,DSN1,DDOST,HINT1,DGCR8,SAFB,HAGHL,RWDD4,FTSJ1,LMBR1,NCLN,BEND3,EYA2,DYNC1LI2,MANBA,B4GALT5,SLC41A1,FAM76A,TKT,CBLL1,ARGLU1,LANCL1,POFUT1,FAM8A1,HEATR5B,HLA-A,EBP,RFWD3,NDUFA2,FUT8,BTF3L4,PTPN11,MRPL54,FEM1B,RPL19,CNN2,NDUFA3,MTX2,MSH6,PDLIM2,LONRF3,RFXANK,FBXO9,GUF1,RPL32,ZHX1,NDUFS5,WDR91,GPR89B,HIGD2A,ZBED3,RORB,POLA2,ZNF76,COPA,UQCR10,HMGXB3,ABCB10,COMMD5,MAP1LC3B,DST,RAB35,SIVA1,GPATCH1,DRAM2,DEAF1,SNRNP200,LAP3,NCK1,VHL,SREK1,ARHGDIB,PITPNB,HSPB11,BRWD1,PPM1G,SH3GLB2,CRCP,BAZ1B,CAB39,ACBD4,STK11,CLU,CHEK2,ZSWIM3,TSTD2,MRPL13,CHPT1,DCAF5,CAPN1,UBE2D3,NSMCE4A,PPP1R12A,ZCCHC8,GORASP1,UBXN1,NACA,RPL15,PCSK7,THRAP3,QSOX2,TTF1,PRPF18,CHKA,DTL,MED10,ZRANB1,MCPH1,SLC12A2,ATP6V0D1,CSNK1G3,CREG1,NUDT4,RPL6,VKORC1,SLTM,EVC2,KLHL15,SIAH2,SLC16A1,EHD4,SNRNP70,C11orf1,APOL2,N4BP2L2,SNX27,CHMP2A,CORO7,FEZ2,UCK2,PMS2,UCK1,CLCC1,EXT2,MXD1,USP5,HNRNPA2B1,SAP130,NVL,PPP6C,CYB5R1,ZNF770,EBAG9,RNF25,PCGF6,METTL2A,FAM72B,PON2,HNRNPR,STAT6,HPS5,MAPK1,BRD9,TMEM33,NAT14,DNAJC2,TRIP12,SHPRH,SCYL1,VPS45,GFM2,SPPL2A,FASTKD3,FGFR3,MZT2A,PPIG,ZDHHC13,TMEM99,H2AFY,NDUFS8,ATG13,ERI3,FBL,SLC35A1,FRMD8,MICAL3,TGFB1,B3GALT6,ELOVL5,HEMK1,TIMMDC1,HELB,PSPC1,MIER1,SCFD2,NDRG3,MTMR3,MEGF9,ACAT1,CENPT,PLOD3,RAB3IL1,RAB14,ADD1,KDM4A,MRPS15,XIAP,DHX8,GLUD1,ANKRD23,CDK5,CALM2,PSMD1,NEK6,NSRP1,RABGAP1L,SRSF4,FNIP2,KCNAB2,PCBP2,PLK3,ZNF672,HSDL1,MRPL43,TOPORS,MCL1,PPFIA3,SMC2,ICMT,SLC50A1,STOML2,LIMK1,ZNF689,PRDX5,ATE1,MLYCD,ST3GAL2,ATP6V0C,FBXL3,TFDP2,E2F2,PFKP,AAAS,DDX42,SSRP1,MRPL9,MRPS2,STRN4,TOP2B,ZNRF3,TMED3,DDRGK1,RAVER2,GNS,INTS7,INPP5A,MCM5,PHF14,ZNF326,NAGPA,TIMM8B,ETV3,TSPAN31,DHX29,TEX10,MAN1B1,RPS10,CBFA2T2,ABCF1,RHOB,LRRC14B,DTWD1,PTPRF,SCARB2,CCDC86,DUSP3,SLAIN1,MDH1,HEXA,RNF139,SNX14,ZNF296,TRERF1,UBR2,CHD1L,ACTR3,WDTC1,MYH9,CREBL2,NIPA2,PRKACA,SAFB2,STAM,ARL6IP6,RAB21,SP100,ZKSCAN1,DDA1,ANKRD13C,MAVS,CEP63,TMEM136,RBM15,ATF2,DCTN1,SHOC2,PSRC1,MAP4K4,WBP2,ATP6V0A1,NDUFA7,DNAJA1,TAZ,TAF2,SEC61A1,WDR7,RPLP1,CBLN2,RBMS1,FUS,GEN1,LRP8,COIL,LRCH1,GALK1,RPS2,SESTD1,TRAK1,JMJD6,SIKE1,AKT1S1,KRI1,FBXO3,ERH,GATC,PPP1R8,PRDM4,GTSE1,GEMIN6,DCP1A,SGCB,S100A6,IMPA2,NUDC,PDPK1,TK1,GUK1,TNFAIP3,GALC,ZNF512,KIAA0930,MRPS10,DDX39A,RPA1,ZNF180,ZNF862,KEAP1,POLE,TATDN2,PITX1,CAPN7,LRPPRC,PML,HMGB2,USF2,ANAPC4,SRM,DDX47,MCCC1,CDC42SE2,S1PR2,CDIPT,KCMF1,SSR1,LIN9,PCNA,ZNF639,TRMU,PIK3R2,ETV6,PPCDC,TXLNA,FAM86C1,MYBL1,MRPL32,CCAR1,ABCC5,PBXIP1,TLK1,MRPL12,EZR,LNX2,LRP5,BRCA1,PRKRA,STX16,EPB41,OPTN,SEPT1,SOCS4,QRSL1,PIEZO1,GLCCI1,NUDT11,GEMIN7,LZTR1,RACGAP1,PPP3CB,B4GALT4,RLF,RAPGEF6,SNRNP25,RB1,VASP,MED8,VMP1,PPIL2,MEA1,TIMELESS,AHDC1,ALDH18A1,TMEM8A,ABCC1,PREB,TRAPPC9,AACS,MEMO1,KRAS,RTF1,UBE4B,NFATC2IP,LY6E,ARPC1A,ZNF174,PSMC4,GOLGA4,SYNCRIP,PRPS2,NIPA1,TIGD2,RNF114,FOXM1,MRPL39,XAB2,DUSP22,COMMD8,RPL11,CSDE1,MDM2,CORO1A,METTL9,MINPP1,POC5,DVL2,GM2A,PSMA8,COQ10B,CPOX,TIGD5,SLC26A6,CYP20A1,PRPF3,TXNL4A,RPSA,SRSF1,DNAJC10,SCAP,ZNF700,PLEKHG4B,TIMM17A,FAU,LTA4H,AP2S1,USP53,CTDP1,MIF4GD,CDT1,ARID5A,SUMF1,GGA2,AP3S1,CSNK1A1,RMI1,TFRC,PTPN2,IRF4,STARD9,GSTK1,NDUFV1,SLC1A4,CWC27,SLC35B4,DDX31,ABCD1,RPAP3,CNTN5,SNX2,ZMYM5,CCDC34,CHCHD6,BSDC1,KPNA4,CDKN2AIPNL,FBXO41,BIRC5,TFE3,SNAP29,CDCA7L,PKD2,ACADM,CHMP7,SAT2,GCSH,ZNF496,TMEM109,TAP1,NHLRC3,IKBIP,EIF1B,ELMOD2,KIFC1,DBNDD1,RNASEK,CDC25B,PRADC1,DNMT1,NOL12,USO1,AKT2,NOL8,GNG7,AURKB,MCFD2,SLC25A5,ZFAND5,MAK16,STT3A,TMED10,PSMD8,EIF2D,ITGB1,PTPN7,UQCRH,RRS1,ARRB2,RTN3,SVIP,DDX58,WSB2,PPIB,MUT,GMFG,HLA-E,NDUFA4,MAN2B1,METTL3,CFLAR,NDUFS4,RNF121,MEX3C,KLF16,HDAC7,DAD1,BDH1,PCYT2,GNAI2,ANKHD1,TERF2,MORC3,KCTD20,SEPT8,DCTD,TOMM40,ADSS,SERTAD2,SERF2,ZFP92,NSF,DCK,ERGIC3,ACLY,LPCAT4,VCPIP1,YY1,PPP6R2,MAP3K5,PPP6R3,RNF14,CDK2,ZC3HAV1,SYS1,ZBTB37,URB2,EIF3D,MAGED1,KLHL18,ADPGK,SLC25A44,AP1B1,SDHA,PHC2,CRKL,MOAP1,TERF2IP,CYHR1,ZNF75D,SHC1,UCHL5,NAA35,TMBIM1,CCT2,CDKN2AIP,MKLN1,GALK2,CDC23,SHCBP1,AP4E1,PRDM11,VEZF1,PPP2R5A,ACYP1,STAT1,PPA2,TRIM32,RHEBL1,C1orf112,MRI1,TCF3,BRAP,AGPAT3,MYNN,SDF2L1,SPR,RAB11A,REEP5,FOXO3,MAD2L2,CCDC28A,PIP5K1C,RBM17,MAT2B,PTEN,CENPJ,TAGLN2,CREB1,SMC4,RNASEH2C,NEK7,NET1,PARP4,TBRG4,ANAPC2,RPL27A,YIF1A,SGSH,HGS,TTLL4,SLC38A7,MFAP1,CCDC69,BRWD3,ESYT2,SKA3,NPHP4,UBE2E2,HNRNPAB,PLXNC1,TMEM184B,ST13,DNAJC24,ZNF107,KIF2C,SLC29A1,AGFG1,SIRT2,FKBP2,USP48,SNRPD3,UBQLN2,CUTC,EDC3,UBLCP1,ZNF804A,RAP1A,THADA,EIF4A3,AP3S2,ATG3,DPYSL2,PPP1R12C,AKR1B1,NDUFB9,JOSD1,RP2,TTC4,TECR,ARID4A,FGFR1OP2,TIMM50,TDP1,DPM1,FOPNL,SLC16A7,WDR82,SLC25A22,STK17B,DHX15,CHAF1A,GEMIN5,COPS6,SASS6,RPS26,PSMC1,SLC12A7,TBC1D12,TM9SF4,ZNF768,UFC1,MED13L,TIA1,MEF2A,EPHX2,PITHD1,RHBDD1,NFATC3,BANF1,BUD31,ZNF335,YBX1,KNTC1,ACAD8,UBE3C,ZNF189,ALDH9A1,KDELR1,TSTA3,CIC,PSMA1,NAP1L1,EXOC4,KIAA1328,PITPNA,NAA20,PTDSS1,MZT2B,PDSS2,C7orf26,TMEM106C,IMMT,ASH1L,CHERP,WDYHV1,PLAGL2,CHKB,IRF3,TWF2,ANKRD28,FARSA,SAR1A,APOOL,PDIA6,ACSL5,TOR1AIP2,AZI2,GFER,RAD54B,TMEM41A,DAP3,ZNF317,GADD45B,AKNA,REEP4,CBX4,MIF,KIF3B,GOLPH3L,SH2D3A,CASP6,TOR3A,SRGN,DBF4,MFSD10,SAC3D1,CTNNBL1,YIF1B,CLDND1,TTC17,SLC25A1,GINS1,CSNK1G2,TELO2,ADAM17,HMGN1,NASP,ASPM,PRKAR1B,SYMPK,TARS,SNRPA,MAPK3,HSPA1B,HLA-B,ATAD2,PLAA,ZNF330,OSBPL8,KBTBD7,PREPL |
| 1.171e-23 | -52.80 | establishment of localization in cell | biological process | GO:0051649 | 1674 | 402 | 17256 | 2622 |
TMED7,RAB14,NUP188,PDCD6IP,TSC2,TAP1,AP3M2,TGOLN2,CCNB1,SYNRG,RIC1,PARK7,FBXO22,MIS12,RPL23A,KIFC1,CDK5,NAPG,SNUPN,RABGAP1L,RAB4A,SRSF4,AP1M1,DNM2,AP2B1,NUP153,TFG,SEH1L,SRSF10,SRP72,USO1,RHOBTB3,TMEM115,AKT2,DDX20,PPFIA3,NUTF2,ICMT,MCFD2,RAB22A,RAB2B,ARF4,STOML2,HHEX,WAS,MID1IP1,TMED10,RPS27A,RPS14,MAP4,EIF2D,VIPAS39,RRS1,NMD3,LONP2,AAAS,NXT2,COX5B,DNAJC5,GGA1,SEC61G,RAB23,KIF23,TMED3,PSEN1,VPS25,COPG2,SPAG5,NPLOC4,COPB2,ATG4A,CD59,SNX18,RIMS3,FBXO7,TNPO3,GEMIN4,CYC1,PIKFYVE,CPSF4,SYTL3,NUP85,PPP6R1,TMED2,TERF2,SRSF11,NAGPA,EIF5A,TIMM8B,GCC2,ERO1A,RPS10,RPS24,SSR2,CAPZA2,SRSF5,ADRB2,MTX1,TOMM40,PTTG1IP,FXR1,GOSR1,RHOB,DERL1,SEC31A,SCARB2,KPNA1,GOLGA2,NSF,FAM83D,PPP3R1,NDE1,PPP6R3,NRBP1,NUP58,ALS2,ANKRD27,NDC1,SARNP,SYS1,RAB11B,RAF1,ANK3,ACTR3,VTI1A,MYH9,TBC1D13,NUF2,AP1B1,STAM,APP,MOAP1,CLUAP1,RAB21,ATP2A2,TBC1D22A,TBC1D14,NUP107,TNPO2,TAP2,ZC3H3,DCTN1,SNX8,SEC61B,PSRC1,GOPC,RPL38,CUL3,RNPS1,POLR2D,SLBP,HTATIP2,NUSAP1,RAB1A,CDC23,AP4E1,ERC1,PEX5,CHMP4A,HSPA4,SEC61A1,VPS26B,RAB24,RPLP1,SEL1L,SNRPG,PITRM1,CSNK1D,TUBB,DYNC1LI2,RPS2,SRSF6,TRAK1,ATP5F1B,SPDL1,IFT27,RAB11A,HEATR5B,SAPCD2,PIP5K1C,PDCD10,RPL17,GEMIN6,RPL19,UPF2,MTX2,IFT46,TPCN1,SPTAN1,PPP3CA,DENND1B,RPL8,RAB3IP,RHOT1,DDX39A,RPL27A,PICALM,YIF1A,KIF18A,HGS,RPL32,ATP5MC3,STX18,LRPPRC,PML,SSNA1,WDR91,YWHAH,ESPL1,IPO4,VPS29,SNAPIN,POLA2,MTX3,COPA,THOC1,NF1,RBM8A,SNX15,ALKBH5,KIF2C,AGFG1,SNRPD3,BECN1,ATP5PF,SEC16A,SSR1,DST,RAB8A,NUP210,CDC42,TIMM23,EIF4A3,AP3S2,RAB35,ATG3,KIF22,TIMM50,CDC37,FYTTD1,LARS,SNRPB,TLK1,EZR,STX16,RAB5B,LSG1,RPL37,GEMIN5,TBC1D17,TIMM13,HSPB11,GRIPAP1,TIMM29,MIA2,KPNA2,VPS4A,DVL1,CLU,CLN3,RPS26,C2CD5,GEMIN7,STARD3NL,TBC1D12,RPS15,GORASP1,PHB2,CENPF,RPL15,RAB6A,XPO7,RHBDD1,NUP205,KIF13B,BANF1,CAPZA1,ARL6IP1,KIFAP3,GLE1,MCPH1,PREB,KDELR1,TRAPPC9,RPL6,SYVN1,ZDHHC3,BBS12,RPL36,TSC1,PCM1,SNAP23,CDCA5,EXOC4,ZDHHC7,SIL1,NUP62,YWHAZ,CTSA,ATP5F1A,EHD4,UNC13C,SNX27,CHMP2A,CORO7,TOMM20,RPLP2,CHERP,DYNLL1,COPE,ZFYVE21,LYN,RPAIN,BCAP31,RPL11,HNRNPA2B1,ANKRD28,ANKLE1,SAR1A,KIF14,PPP6C,BCAP29,CORO1A,AHCYL1,CLTB,CHTOP,LMAN1,F2R,CHP1,RPL29,NXT1,RPL35,PPT1,RAB7A,ATXN1,NUP155,BICD2,ERBIN,CHMP2B,PEF1,RPS9,TMEM201,RPSA,SRSF1,SURF4,VPS26C,TIMM17A,CEP55,ARNTL,AP1S1,ANP32E,CHMP4B,SMURF1,AP2S1,ABCA1,PARD3,TMEM33,KIF3B,CDC40,RAE1,CDT1,DCTN2,NUP54,VPS45,CDCA8,ARFIP2,TIMM21,GGA2,AP3S1,SCYL2,KIF5B,KLHL20,SEC24C,ANP32A,ARHGEF2,YIF1B,ABCD1,STAT3,MYO5A,RBM15B,TGFB1,ZDHHC18,SNX2,COG1,WDR81,ATP5MF,RHOT2,SYMPK,MFN2,LEMD2,RAB18,SEC23IP,KPNA4,UPF1,PDCD6,GOLGA7,SNAP29,PKD2,SPCS3,SRSF3,CHMP7,TERF1 |
| 1.425e-23 | -52.61 | intracellular transport | biological process | GO:0046907 | 1449 | 359 | 17256 | 2622 |
TMED7,RAB14,NUP188,TSC2,TAP1,AP3M2,TGOLN2,SYNRG,RIC1,FBXO22,RPL23A,CDK5,NAPG,SNUPN,RABGAP1L,RAB4A,SRSF4,AP1M1,DNM2,AP2B1,NUP153,TFG,SEH1L,SRSF10,SRP72,USO1,RHOBTB3,TMEM115,AKT2,DDX20,NUTF2,ICMT,MCFD2,RAB22A,RAB2B,ARF4,STOML2,HHEX,WAS,MID1IP1,TMED10,RPS27A,RPS14,EIF2D,VIPAS39,RRS1,NMD3,LONP2,AAAS,NXT2,COX5B,DNAJC5,GGA1,SEC61G,RAB23,KIF23,TMED3,PSEN1,VPS25,COPG2,NPLOC4,COPB2,ATG4A,CD59,SNX18,RIMS3,FBXO7,TNPO3,GEMIN4,CYC1,PIKFYVE,CPSF4,SYTL3,NUP85,PPP6R1,TMED2,TERF2,SRSF11,NAGPA,EIF5A,TIMM8B,GCC2,RPS10,RPS24,SSR2,CAPZA2,SRSF5,ADRB2,MTX1,TOMM40,PTTG1IP,FXR1,GOSR1,RHOB,DERL1,SEC31A,SCARB2,KPNA1,GOLGA2,NSF,PPP3R1,NDE1,PPP6R3,NRBP1,NUP58,ALS2,ANKRD27,NDC1,SARNP,SYS1,RAB11B,ANK3,VTI1A,TBC1D13,AP1B1,STAM,APP,CLUAP1,RAB21,ATP2A2,TBC1D22A,TBC1D14,NUP107,TNPO2,TAP2,ZC3H3,DCTN1,SNX8,SEC61B,GOPC,CUL3,RNPS1,POLR2D,RPL38,SLBP,HTATIP2,RAB1A,AP4E1,ERC1,PEX5,CHMP4A,HSPA4,SEC61A1,VPS26B,RAB24,RPLP1,SEL1L,SNRPG,PITRM1,CSNK1D,TUBB,DYNC1LI2,RPS2,SRSF6,TRAK1,ATP5F1B,IFT27,RAB11A,HEATR5B,PIP5K1C,RPL17,GEMIN6,RPL19,UPF2,MTX2,IFT46,SPTAN1,PPP3CA,DENND1B,RPL8,RAB3IP,RHOT1,DDX39A,RPL27A,PICALM,YIF1A,HGS,RPL32,ATP5MC3,STX18,LRPPRC,PML,SSNA1,WDR91,YWHAH,IPO4,VPS29,SNAPIN,POLA2,MTX3,COPA,THOC1,RBM8A,SNX15,ALKBH5,AGFG1,SNRPD3,BECN1,ATP5PF,SEC16A,SSR1,DST,RAB8A,NUP210,CDC42,TIMM23,EIF4A3,AP3S2,RAB35,ATG3,TIMM50,CDC37,FYTTD1,LARS,SNRPB,TLK1,RAB5B,STX16,LSG1,RPL37,GEMIN5,TBC1D17,TIMM13,HSPB11,GRIPAP1,TIMM29,MIA2,KPNA2,VPS4A,CLU,CLN3,RPS26,C2CD5,GEMIN7,RPS15,TBC1D12,GORASP1,PHB2,RPL15,RAB6A,XPO7,RHBDD1,NUP205,KIF13B,BANF1,CAPZA1,ARL6IP1,KIFAP3,GLE1,PREB,KDELR1,TRAPPC9,RPL6,SYVN1,ZDHHC3,BBS12,RPL36,TSC1,PCM1,SNAP23,EXOC4,ZDHHC7,SIL1,NUP62,CTSA,ATP5F1A,EHD4,UNC13C,CHMP2A,SNX27,CORO7,TOMM20,RPLP2,DYNLL1,COPE,ZFYVE21,LYN,RPAIN,BCAP31,RPL11,HNRNPA2B1,ANKRD28,ANKLE1,SAR1A,KIF14,PPP6C,BCAP29,CORO1A,AHCYL1,CLTB,CHTOP,LMAN1,CHP1,RPL29,NXT1,RPL35,RAB7A,ATXN1,NUP155,BICD2,ERBIN,CHMP2B,PEF1,RPS9,TMEM201,RPSA,SRSF1,SURF4,VPS26C,TIMM17A,ARNTL,AP1S1,ANP32E,CHMP4B,SMURF1,AP2S1,ABCA1,PARD3,TMEM33,KIF3B,CDC40,RAE1,DCTN2,NUP54,VPS45,ARFIP2,TIMM21,GGA2,AP3S1,SCYL2,KIF5B,KLHL20,SEC24C,ANP32A,ARHGEF2,YIF1B,ABCD1,STAT3,MYO5A,RBM15B,TGFB1,ZDHHC18,SNX2,COG1,WDR81,ATP5MF,RHOT2,SYMPK,MFN2,RAB18,SEC23IP,UPF1,PDCD6,KPNA4,GOLGA7,SNAP29,SPCS3,SRSF3,CHMP7 |
| 1.543e-23 | -52.53 | MGGAAGTG_V$GABP_B | MSigDB lists | MGGAAGTG_V$GABP_B | 717 | 211 | 17377 | 2626 |
COX15,ZBTB10,DDX47,NF1,PRKCSH,YTHDF3,DHX8,COMMD5,SYNRG,CUTC,CMTM6,GIT2,FBXO22,EDC3,BCAT2,C14orf119,ZER1,CDK5,USF1,AP3S2,PIK3R2,SRSF4,AP1M1,NOC2L,TAF5L,ECD,PRADC1,DNMT1,MTPN,ZNF800,CDC5L,VPS13B,NOL12,ERCC1,NRAS,TLK1,WDHD1,CBFB,RAB2B,C1orf122,DPYSL3,RPL37,SEPT1,FBXO28,PRDX5,SOCS4,UQCRH,ACTB,GALNT10,ARRB2,NAA60,ATP6V0E1,ZMAT3,AAAS,UBE2D3,HSPH1,MAPRE1,LIME1,TMUB1,ZCCHC9,PHB2,PHF23,GGA1,ZNF768,UFC1,UBXN1,GSPT2,CIB1,CDK13,ZNF79,TTF1,WDR48,NFATC3,VASP,VMP1,RINL,SSBP3,CAPZA1,CTR9,TNPO3,OSTF1,MORC3,EIF5A,ETV3,PRIM2,WDR1,AMD1,MFNG,BCLAF1,TOMM40,C9orf40,ARHGAP15,SEC31A,MAGED2,FNTA,ITPRIPL1,SYNCRIP,PALB2,ARAP1,APPL2,TCOF1,WIPI2,ZNF830,MRPL3,ADNP2,TCF12,TRIM41,FEZ2,CHERP,CAST,MAGED1,SLC39A13,MON1B,BCL2L1,POMP,INO80E,C2orf49,PRKACA,ZADH2,PAIP2,VAV1,SEC11A,SHC1,RALB,MTMR4,PPME1,CSTF1,RLIM,ACSL5,SLC39A9,ERF,RAB7A,LYRM1,SMU1,RNPS1,PSMB7,E2F3,WIPF1,NUP155,CADM1,HERPUD2,AP4E1,ARL5B,GAR1,RPSA,SUPT16H,TAF2,SUGP1,DDOST,TIMM17A,HPS5,CORO1C,KLHDC4,GEN1,BRD9,XRCC4,ZBTB11,TMEM33,CWC25,KIF3B,CMAS,TMBIM4,SLC41A1,RAE1,EYA1,SMC6,ARFIP2,UBE4A,CDK11B,TFRC,DNAJB9,PTPN2,KIF5B,RPA2,ERH,CTSS,SEC24C,SLC38A10,CITED2,TMX1,PDLIM2,NIPAL3,PPAN,TTPAL,ELOVL5,PPP3CA,ACP2,MLEC,ZFP64,NASP,ZNF512,BTAF1,PPP1R21,ATP2C1,TUFM,PNPLA8,PCGF1,DDX39A,CDK11A,PICALM,MFN2,TMEM127,SEC23IP,ATP6V1D,FAM110A,ELMO1,TFE3,PML,PPP1R11,ZRANB2,THAP5 |
| 1.560e-23 | -52.51 | IFI16 (interferon gamma inducible protein 16) | protein interactions | 3428 | 356 | 135 | 17029 | 2761 |
RAB14,DDX47,PDCD6IP,NUP188,ADD1,RBM8A,YTHDC2,DHX8,CSNK2A1,EBNA1BP2,BRIX1,KRR1,NOL11,CDC42,NOC2L,RPF2,NUP153,TFG,FTSJ3,SEH1L,CARM1,SRP72,EXOSC6,AATF,BAZ2A,MKI67,BRCA1,UTP3,PBRM1,PRKRA,RFC2,MAK16,UBTF,PAF1,BAZ1B,BTF3,RRS1,FAM208A,AAAS,SSRP1,CCDC137,LZTR1,CTCF,KIF23,RACGAP1,TOP2B,NUP205,LYAR,DDX56,EXOSC7,RBM34,MBD2,PHF14,GLE1,NUP85,HP1BP3,DDX28,PRRC2A,DHX29,TEX10,ZNF574,GTPBP4,UTP15,FXR1,CCDC86,RBM25,NUP62,NUP58,ZC3HAV1,USP7,NDC1,SART1,MPHOSPH8,URB2,DYNLL1,XAB2,TOR1AIP1,APP,AHCTF1,MDM2,SP100,UTP18,NVL,NUP107,RBM15,UTP4,RFC3,KAT7,SMU1,CRNKL1,NFATC2,USP36,DHX57,SUPT16H,EIF3K,NSA2,DNAJC10,DHX16,TBL3,PDCD11,COIL,NIFK,TRIP12,RAE1,PDAP1,AGO2,NUP54,TKT,NKRF,PIP4K2A,HLA-A,KRI1,HUWE1,H2AFY,PPAN,YTHDC1,STAU1,DDX24,PSPC1,ZNF512,WDR18,BMS1,POLR2A,MAPK3,CBX3,LEMD2,UTP20,INF2,UPF1,TRIM26,ATAD2,OSBPL8,PML,BYSL,DDX52 |
| 1.701e-23 | -52.43 | GO_CATALYTIC_COMPLEX | MSigDB lists | GO_CATALYTIC_COMPLEX | 983 | 266 | 17377 | 2626 |
MAX,NDUFB6,CXXC1,CUL1,CCNL2,UBE2I,POLR3K,PARK7,TAF5L,SPTSSA,ZNRD1,USP34,ERCC1,GNG7,TOPORS,DCUN1D5,USP22,CCNF,FOXRED1,CLNS1A,BRMS1,RAD18,STT3A,OGT,DHTKD1,FBXL3,HDAC2,NDUFV2,POLR2K,PRKAA1,STRN4,KCTD17,RRM1,NDUFA4,CYCS,EZH1,SUPT7L,METTL3,CDC73,NDUFS7,NDUFS4,CFLAR,RPN1,KLHL5,INTS7,HDAC7,DAD1,FBXO7,PPP4R1,FBXL7,GNAI2,PHKG2,PIGT,RB1CC1,MTA2,TEX10,TWISTNB,FNTA,POLR2J,PPP3R1,DCAF11,PTAR1,APPL2,MAP3K5,YY1,RNF14,CDK2,TRERF1,UBR2,SUZ12,KLHL18,INO80E,PRKACA,SDHA,ANKIB1,PHC2,ATP2A2,UCHL5,INTS12,CDKN1B,ANAPC7,RNF19A,GPD1L,NAA35,RPRD1B,CDK12,DCTN1,SAP30,SHOC2,POLR2L,KAT7,POLR2D,CUL3,ELP4,NDUFA7,DNAJA1,EDF1,CDC23,ERC1,MAT2A,TAF2,PPP2CA,CDC16,PPP2R5A,DDOST,HINT1,DGCR8,SEL1L,TICAM1,SNRPG,DYNC1LI2,NCOR2,NDUFS1,TRMT6,BRAP,CBLL1,SDF2L1,UBE4A,WDR5,MAD2L2,WWP2,GTF2F1,MAT2B,CCNK,PPP1R3B,ERH,NDUFA2,NDUFB4,PRDM4,NAA50,OSTC,NDUFA3,GTF2H2,FBXL19,PPP3CA,KAT2A,FBXO9,ANAPC2,FADD,POLR2A,GNA12,FBXO21,KEAP1,POLE,MAGT1,PRDX3,PPP1R11,NDUFS5,TAF6,ANAPC4,DDB1,CCNC,MIB2,POLA2,PPP1R15B,UQCR10,CSNK2A1,TAF6L,SNRPD3,BECN1,ZER1,METTL14,INTS1,ATG3,POP7,PIK3R2,NDUFB9,METTL1,RBX1,NCK1,DPM1,SNRPB,VHL,RRM2,WDR82,UBE2V1,BRCA1,KRTCAP2,PRPSAP1,PAF1,CHD3,CAB39,CRCP,ACTB,DCAF5,PPP1R2,PPP1R12A,ZNF768,CDK13,PPP3CB,DTL,RB1,MED10,MBD2,ZNF335,CTR9,POLR2I,DCAF8,RTF1,SYVN1,UBE4B,APPL1,CAND1,SDHB,GNAS,MBIP,CDC27,KLHL15,TBPL1,RUVBL2,NAA20,RBBP4,PDSS2,BCCIP,NDUFA5,PRKAB1,TRAF7,DYNLL1,MEAF6,SAP130,FARSA,PDK2,BRPF3,CD3EAP,RPN2,DNAL4,GM2A,POLR2G,PGGT1B,PCGF6,OGDH,NDUFB1,MBD3,PDHX,ATP1A1,STK38,NDUFA11,PPP2R2D,CBX4,INTS2,GCLM,CTDP1,KLHL21,DCTN2,DCUN1D4,NDUFV1,KLHL20,H2AFY,NDUFS8,ATG13,POLR1B,PPP1R9B,RPRD1A,DCAF6,HELB,ABCF2,PRKAR1B,POLR3GL,MEN1,HSPA1B,GOLGA7,KBTBD7,SPCS3,TAF12,UBE2C,GCSH |
| 1.812e-23 | -52.37 | ACEVEDO_LIVER_CANCER_UP | MSigDB lists | ACEVEDO_LIVER_CANCER_UP | 895 | 248 | 17377 | 2626 |
TMED7,H2AFZ,COPA,MTX3,WDR13,TMEM109,TAP1,YTHDF3,UBE2Q1,ABCB10,UBQLN2,EIF1B,UBLCP1,SSR1,RPL23A,BCAT2,CDK5,ASAP2,EIF4A3,DNAAF2,IMPAD1,RAB4A,NUP153,MARCH2,RNF26,TFG,PLCL2,LRRC59,SMARCE1,DNMT1,MTPN,WDR41,CDC5L,USP34,SRP72,RHOBTB3,NRAS,DPM1,LAP3,RBX1,GMFB,PSMG1,SUMF2,UTP3,MCFD2,SLC50A1,DHX15,RHEB,ABHD5,TRAM2,HSPB11,EIF4ENIF1,RBM47,WDR11,FBXO28,TMED10,RPS27A,IARS2,MPV17,UQCRH,KPNA2,MRPL13,NGLY1,NMD3,ATP6V0E1,SMNDC1,HDAC2,WSB2,MRPL9,ZCCHC9,GMFG,SCOC,GORASP1,PHF23,HLA-E,UFC1,LAMTOR3,CTCF,DNAJB1,PMF1,PDCD7,ASXL2,METTL3,VPS25,NUP205,PRPF18,COPB2,CHKA,LRRC14,MCTS1,DTL,FAM192A,LYAR,SUB1,UBE2Q2,SMC3,ARPC5,LRRC8D,DAD1,RBM34,KIFAP3,PIK3IP1,UBE3C,VOPP1,NTPCR,PIGT,RB1CC1,DHX29,NQO2,GTPBP4,GBA,C1orf35,SSR2,PTTG1IP,DTWD1,DERL1,MBIP,EPRS,SERTAD2,GOLGA4,UAP1,RBMX,ACLY,FAM83D,TMEM14A,TSEN15,PRKAB1,IMMT,CKLF,SUMO2,ACTR3,TOR1AIP1,UCK2,RMI2,TWF2,GGPS1,ABHD16A,MRPL50,AHCTF1,PSMA6,CCNA2,STRBP,SAR1A,UCHL5,SEPT11,RPN2,RNASEH2A,TP53BP2,MINPP1,TALDO1,CHTOP,PDIA6,CDK12,TMEM9,SAP30L,TMEM14C,KDM3B,HMGN4,PPT1,SLC26A6,TIGD5,ATXN1,MTMR6,NUSAP1,BOLA1,PRPF3,CHMP2B,EDEM2,SERP1,EIF3H,CHCHD3,PON2,CDC16,PPP2R5A,DSN1,HNRNPR,DHX16,NSMCE2,CHCHD1,RPLP1,LMBR1,H2AFX,CANT1,ATF6,FKBP5,USP13,COMMD10,MIF4GD,GOLPH3L,TRIP12,RRP15,SRGN,VPS45,KLF13,MYNN,LANCL1,AP3S1,ETS1,RMI1,SCYL2,WRB,BZW2,RRP36,XPR1,RGS1,SPPL2A,SRXN1,PSMD2,KLHL20,CWC27,RPL17,PRC1,LTN1,CLDND1,TAGLN2,PTGES3,OSTC,ORC3,CNPY3,TXNL1,ELOVL5,GTF3C6,TK1,SNX2,ASPM,TMEM126B,BTAF1,METTL5,LLPH,RAB3IP,ZFR,FADD,SMAP2,HSPA1B,HLA-B,RAB18,SEC23IP,C1orf131,MFAP1,HNRNPH3,BBX,HMGB2,TAF12,PREPL,TATDN1,IGBP1,PURA,IPO4 |
| 1.817e-23 | -52.36 | BERENJENO_TRANSFORMED_BY_RHOA_UP | MSigDB lists | BERENJENO_TRANSFORMED_BY_RHOA_UP | 508 | 165 | 17377 | 2626 |
SRM,POLA2,H2AFZ,TXN,NOP2,EBNA1BP2,KIF2C,FKBP2,SNRPD3,CCNB1,POLR3K,LIN9,PA2G4,PCNA,TIMM23,RPF2,KIF22,LRRC59,DNMT1,FTSJ3,TACC3,HARS,RAD51AP1,NSUN2,MKI67,MRPL12,EZR,WDHD1,CDC6,AURKB,BRCA1,SMC2,CCNF,ANLN,MCM2,ODC1,MAK16,ASF1B,DPYSL3,PRIM1,CDCA4,KPNA2,RRS1,SSRP1,SEPHS2,HSPH1,NSMCE4A,RRM1,KIF23,RACGAP1,CYCS,PMF1,FAM136A,DTL,C4orf3,MCM5,BANF1,MSH2,EI24,TIMELESS,AHCY,NUP85,PPA1,FAM171A1,IFRD1,PRIM2,ELL2,MYBL2,PSMA1,USP10,MRPL16,TOMM40,C9orf40,PSMB3,RBM38,MTHFD2,PDLIM1,DCK,CDCA5,RUVBL2,NDE1,CYTIP,FEZ2,IVNS1ABP,FOXM1,SUZ12,PTTG1,SLC2A1,UCK2,TMEM97,ORC1,STMN1,TCF19,CHD1,PHC2,CYHR1,RRN3,CCNA2,MDM2,UTP18,UCHL5,NUP107,MRPL34,TARDBP,RNASEH2A,TALDO1,RPRD1B,SAP30,ACSL5,CLCN3,RFC3,NXT1,RNPS1,SLBP,FRAT2,DNAJC9,NUSAP1,GAR1,SRSF1,PON2,HSPA4,RBL1,TBL3,CORO1C,GCLM,DNAJC2,PKP4,MCM10,CDT1,CDCA8,NUP54,PNO1,TFRC,GART,PRC1,H2AFY,GTSE1,TAGLN2,PTGES3,FBL,SMC4,TK1,NASP,HMGN5,TNFAIP3,RNASEH2C,ASPM,NET1,ABCF2,LDHA,MRPS10,RANGAP1,KIF11,RPA1,FAM110A,BIRC5,TFDP1,MAPK6,CDCA7L,E2F1,LY75,ASNA1,HMGB2,PGAM1,BYSL |
| 1.871e-23 | -52.33 | KIM_ALL_DISORDERS_OLIGODENDROCYTE_NUMBER_CORR_UP | MSigDB lists | KIM_ALL_DISORDERS_OLIGODENDROCYTE_NUMBER_CORR_UP | 718 | 211 | 17377 | 2626 |
IER2,TMEM184B,GNPDA1,AP3M2,AGPAT1,ENSA,CDIPT,OAT,MAP1LC3B,BECN1,SLC20A1,PPP1R16B,ABHD14A,RNF103,SF3B2,CDK5,CALM2,GOT2,DPYSL2,RAD23B,HADHB,AKR1B1,TRA2B,JOSD1,CRY2,TECR,PTPRK,DEAF1,ATG9A,SNRPB,ESYT1,CLNS1A,MAN2A2,RPL37,RPS27A,PSMD8,COX5A,UQCRH,ATP6V0C,ARRB2,PSMC1,OAZ1,PFKP,DDX42,PTOV1,WSB2,COX5B,DHPS,DNAJB2,CTCF,COX4I1,DNAJB1,NCKAP1,MYL6B,NDUFS7,NDUFS4,FKBP1A,DAD1,RIMS3,FAM89B,KIFAP3,AHCY,CYC1,MRPL40,ATP6V0D1,FAM171A1,TMED2,NIPSNAP1,NAGPA,FTL,RPS10,SEPT8,CAPZA2,LY6E,CYFIP2,EIF4G2,CCT8,PSMB3,NCDN,GNAS,MAGED2,PFDN5,POLR2J,NSF,COX7A2L,MDH1,CABIN1,CTSA,GPI,RUVBL2,PTDSS1,EXOC3,CHMP2A,ABCA3,SUCLG1,MAGED1,EIF3D,SUMO2,KIAA0232,COPE,STARD7,SMARCA4,ATP6V1B2,HCFC1R1,SNN,DAZAP2,SDHA,BCAP31,RPL11,SEC11A,FARSA,ATP6V0B,APLP2,PSMA6,PIN1,CLCN6,CORO1A,CLTB,TALDO1,CFL1,GPX4,CCT2,SHOC2,RPL29,RPL35,EID1,DRAP1,WBP2,RNPS1,CIRBP,MTMR6,GLO1,NDUFA7,TMEM147,NDUFB1,MBD3,PEF1,SERP1,TRIM28,PDHX,EIF3G,EIF3K,CDC16,HINT1,DDOST,SCAP,WDR7,RPLP1,SNRPG,FAU,USP11,LTA4H,AP2S1,MIF,SLC30A9,NDUFS1,ANXA6,SCAMP3,KLHL21,DCTN2,TKT,ARFIP2,SLC25A12,GTF3A,LANCL1,PMVK,REEP5,SAC3D1,PIP5K1C,PSMD2,NDUFV1,AHSA1,ARF5,H2AFY,NDUFS8,CLDND1,ERI3,SLC35A1,MTX2,UBE2M,CAMK2G,NUDC,LDHB,SPTAN1,AMPD2,HMGN1,RHOA,CSRP1,RPL8,TUFM,FBXO9,HAGH,SNRPA,PRDX1,ECH1,MAPK3,NUCB1,RPL32,ELMO1,TATDN2,DTX4,PGRMC1,COX8A,PPP1R11,SSNA1,PSAP,IDH3B,TAF6,CD81,HRAS,DDB1 |
| 1.927e-23 | -52.30 | BENPORATH_CYCLING_GENES | MSigDB lists | BENPORATH_CYCLING_GENES | 607 | 187 | 17377 | 2626 |
UBL3,PTMS,KDM4A,RBM8A,AP3M2,DHX8,KIF2C,AGFG1,UBQLN2,CCNB1,BIRC2,MRPL19,FANCI,MBD4,ASPHD2,KIFC1,CDKN2C,PCNA,SNUPN,CDC42,NT5DC1,SUCLG2,KIF22,CDC25B,TACC3,SRSF10,PLK1,RHOBTB3,RAD51AP1,PBK,ZBED5,MKI67,RRM2,ARHGDIB,CDC6,AURKB,BRCA1,CCNF,ANLN,MCM2,RFC2,PRPSAP1,RHEB,ASF1B,CHAF1A,PRIM1,ANKRD10,RAD18,OGT,KPNA2,CHEK2,ROCK1,UBE2D3,HJURP,CLSPN,PPP1R2,MRPS2,CENPF,RAB23,RRM1,KIF23,CTCF,THRAP3,DNAJB1,PSEN1,VPS25,SPAG5,LMNA,CFLAR,DTL,FKBP1A,LYAR,PDXP,INTS7,MCM5,ARL6IP1,MSH2,CTR9,HP1BP3,PRIM2,CIC,NUDT4,AMD1,KRAS,BCLAF1,SRSF5,FXR1,HAUS8,MASTL,SYNCRIP,CDC27,ODF2,FAM83D,PPP6R3,NDE1,CCNB2,SMARCD1,ZNF207,FOXM1,IVNS1ABP,DYNLL1,POC1A,PTTG1,TPX2,NUF2,ORC1,KIAA1147,FLAD1,MDM2,CCNA2,SHC1,KIF14,CDKN1B,TNPO2,SAP30,CDKN2AIP,MND1,RNPS1,SLBP,NUSAP1,KIAA1586,PKMYT1,CADM1,HERPUD2,SHCBP1,PPP2CA,RAD51C,CDC16,ACYP1,TAB2,CCDC14,GOLGA8A,CEP55,STAT1,H2AFX,ANP32E,USP53,ZC3HC1,POLQ,USP13,GCLM,MRI1,CDCA8,CDCA3,AGPAT3,ARGLU1,RMI1,DNAJB9,SLC25A36,KIF5B,RPA2,PRC1,GTSE1,FEM1B,BRD7,CNN2,CENPM,ORC3,SMC4,PPP3CA,NASP,TOP3A,RANGAP1,RPL27A,BORA,KLF6,KIF11,FADD,CBX3,ATAD2,MAGT1,BIRC5,FAM110A,NEIL3,CDCA7L,CAPN7,E2F1,MEGF9,HMGB2,ZRANB2,SRSF3,WDR62,YWHAH,UBE2C,HRAS,ESPL1,GCSH |
| 2.327e-23 | -52.11 | COPS5 (COP9 signalosome subunit 5) | protein interactions | 10987 | 785 | 236 | 17029 | 2761 |
MAX,TXN,HNRNPAB,NOP2,MRPS15,PHRF1,YTHDC2,CUL1,CSNK2A1,EBNA1BP2,SNRPD3,MAPK14,RBM4,PABPC4,FBXO22,RPL23A,CIPC,TRA2B,TFG,ASB6,FTSJ3,PCBP2,SEH1L,CARM1,CDC5L,PLK1,COPS8,SNRNP200,RBX1,VHL,SNRPB,NSUN2,MRPL43,HNRNPF,DDX20,SLC25A5,RFC2,PRPSAP1,DHX15,SMAD2,BRWD1,LUC7L3,RPS14,U2SURP,PRPF4,KPNA2,ACTB,KLHL42,COPS6,PFKP,SSRP1,FUBP1,RPS15,MAPRE1,EWSR1,DHX9,RRM1,TIA1,RPL15,PRPF39,LRRC14,DTL,C12orf10,LYAR,RPN1,DDX56,SMC3,FBXO7,EFTUD2,RTCB,CTPS1,YBX1,RBM3,AHCY,PABPC1,LUC7L2,EIF5A,POLR2I,RBM42,DHX29,DCAF8,NQO2,RPS10,RPL6,GTPBP4,RPS24,KRAS,EXOSC9,MAP4K3,SRSF5,PKM,FXR1,ABCF1,MAP2K2,MATR3,CCT8,CAND1,SDHB,MAGED2,EPRS,NAP1L1,KPNA1,SYNCRIP,KLHL15,DCAF11,YWHAZ,WIPI2,SNRNP70,CDK2,HNRNPDL,RNF139,NRBP1,ZC3HAV1,CDKN2A,USP7,KARS,RPLP2,RAF1,MDH2,CAST,SF3B1,HNRNPUL2,KLHL18,SMARCA4,AP1B1,SAFB2,PCBP1,SDHA,APP,RPL11,CSDE1,SAP130,HNRNPA2B1,MDM2,PSMA6,CCNA2,BABAM2,ZNF302,IARS,STRBP,SIAH1,DDA1,AKAP8,MRPS27,MICU2,CDKN1B,ANAPC7,PDIA6,PRPF19,CCT2,RPL35,RPL38,CIRBP,RNPS1,CUL3,DNAJC9,TOR1AIP2,NUP155,DNAJA1,MEF2D,GFER,TRIM28,RPS9,RPSA,EIF3H,MAT2A,DHX57,BTBD1,SRSF1,DDX17,DNAJC10,HSPA4,HNRNPR,RPLP1,FUS,SNRPG,PDXK,NCOA1,FAU,SMAD4,ABCA1,TUBB,MIF,SLC30A9,RPS2,RRP15,KLHL21,SRSF6,CDT1,AGO2,MYNN,NKRF,WDR5,BLM,CSNK1A1,TUT4,FBXO3,KIF5B,NDUFV1,RPL17,FEM1B,RPL19,COPS7B,FBL,MRPL11,STAT3,UBE2M,HNRNPM,SPTAN1,LDHB,PRKDC,TUFM,RPL8,ILF3,FBXO9,ANAPC2,RPL27A,SNRPA,ZFR,PRDX1,HSPA1B,TPD52L2,FBXO21,UPF1,RPL32,PRDX3,HNRNPH3,PGRMC1,ACAT1,KHSRP,DDX5,CENPT,SRSF3,DDB1,BYSL,DDX52 |
| 2.470e-23 | -52.06 | GO_PROTEIN_LOCALIZATION | MSigDB lists | GO_PROTEIN_LOCALIZATION | 1721 | 408 | 17377 | 2626 |
CCDC93,TMED7,RAB14,NUP188,PDCD6IP,TSC2,TAP1,AP3M2,SYNRG,MIS12,RPL23A,CDK5,NAPG,SNUPN,RABGAP1L,RAB4A,AP1M1,DNM2,AP2B1,NUP153,SEH1L,PGAP2,SRP72,USO1,TMEM115,NRAS,ATG9A,AKT2,TOPORS,MCL1,AURKB,NUTF2,MCFD2,ICMT,RAB22A,PLEKHF2,RAB2B,ARF4,HHEX,SMAD2,TMED10,RPS27A,RPS14,EIF2D,ITGB1,ATP6V0C,BTF3,ARRB2,LONP2,NMD3,ZMAT3,AAAS,DDX42,NXT2,MAPRE1,SEC61G,GGA1,RHOC,CUTA,ACAP1,RAB23,DHX9,TMED3,SUPT7L,PSEN1,COPG2,VPS25,LMNA,NPLOC4,SPAG5,COPB2,ATG4A,SNX18,FBXO7,ATP6V0A2,TNPO3,PIKFYVE,MVP,SYTL3,NUP85,TMED2,MORC3,TERF2,NAGPA,EIF5A,TIMM8B,GCC2,RPS10,RPS24,SSR2,RIT1,MTX1,TOMM40,PTTG1IP,GOSR1,RHOB,SEC31A,DERL1,SCARB2,FNTA,KPNA1,NSF,FAM83D,WIPI2,SNX14,ALS2,RHOG,EXOC3,ANKRD27,ATXN3,SYS1,RAB11B,RAF1,RAC1,GPR89A,ANK3,C5orf30,VTI1A,MYH9,TBC1D13,AP1B1,STAM,TERF2IP,MOAP1,RAB21,AHCTF1,RALB,TBC1D22A,TBC1D14,NUP107,TNPO2,ANKRD13C,TAP2,GCC1,ATP6V1G1,SNX8,SEC61B,GOPC,WBP2,RPL38,ATP6V0A1,DNAJA1,RAB1A,AP4E1,ERC1,SERP1,HSPA4,PEX5,CHMP4A,SEC61A1,RAB24,VPS26B,CCDC14,CORO1C,SEL1L,RPLP1,CSNK1D,RHEBL1,RPS2,MZT1,SCAMP3,MECP2,TRAK1,FLOT1,BTN3A1,IFT27,RAB11A,WRB,JAKMIP1,RPL17,ARF5,AXIN2,DCP1A,RPL19,IFT46,MTX2,PACS2,PPP3CA,TNFAIP3,GUK1,DENND1B,DENND4C,RPL8,RABIF,PACS1,RAB3IP,RHOT1,ZP3,RPL27A,MACF1,SH3GLB1,YIF1A,HGS,KIF18A,KEAP1,RPL32,STX18,PML,ASNA1,SSNA1,CD81,YWHAH,VPS29,FAF1,IPO4,GPR89B,SNAPIN,POLA2,AGRN,COPA,MTX3,SNX15,UBE2Q1,BECN1,SEC16A,RUFY1,SSR1,DLG5,RAB8A,RAP1A,NUP210,CDC42,TIMM23,ATG3,AP3S2,RAB35,PIK3R2,SRI,ZFYVE27,RP2,TIMM50,PTPRK,CDC37,VPS13B,PLK1,MIOS,TLK1,EZR,RAB5B,STX16,LSG1,RHEB,OPTN,NECAP2,PAF1,RPL37,TRAM2,TIMM13,TBC1D17,HSPB11,EIF4ENIF1,UEVLD,TONSL,KPNA2,ROCK1,DVL1,VPS4A,CLU,RPS26,POT1,ATP6V0E1,RPS15,TBC1D12,PHB2,GORASP1,CENPF,NACA,NKD2,LAMTOR3,TIA1,RPL15,RAB6A,XPO7,RAPGEF6,RHBDD1,NUP205,RB1,RINL,KIF13B,PPIL2,ARL6IP1,KIFAP3,YBX1,GLE1,LRSAM1,ATP6V0D1,KDELR1,PREB,RPL6,KRAS,SYVN1,ZDHHC3,BBS12,RPL36,GNAS,GOLGA4,PCM1,SNAP23,EXOC4,SIL1,NUP62,CTSA,YWHAZ,RUVBL2,TOB1,CHMP2A,SNX27,TOMM20,CORO7,RPLP2,DYNLL1,COPE,TOR1AIP1,RRAGC,ATP6V1B2,TWF2,LYN,RPAIN,BCAP31,RPL11,ATP6V0B,MDM2,SAR1A,KIF14,AKAP8,BCAP29,SCAMP4,AHCYL1,LMAN1,CLTB,F2R,DVL2,PRPF19,SNX25,RPL29,RPL35,NXT1,PPT1,RAB7A,TOR1AIP2,NUP155,CHMP2B,TOLLIP,RPS9,RPSA,RHBDF2,SURF4,TULP3,TIMM17A,TOMM6,CEP55,ARNTL,AP1S1,CHMP4B,FAU,SMURF1,MAPK1,TSPAN5,AP2S1,ABCA1,PARD3,TMEM33,KLHL21,EYA1,RAE1,SRGN,DCTN2,NUP54,VPS45,ARF1,GGA2,AP3S1,TFRC,KLHL20,SEC24C,RRBP1,H2AFY,ARHGEF2,STAT3,CAMK2G,MYO5A,TGFB1,ZDHHC18,RHOA,NASP,SNX2,SCFD2,COG1,RHOT2,MAPK3,MFN2,RAB18,KPNA4,PDCD6,ATP6V1D,SEC23IP,GOLGA7,BIRC5,OSBPL8,SNAP29,PKD2,FAM126A,RBPJ,ATP6V1C1,PLOD3,CHMP7,HRAS,RAB3IL1 |
| 2.497e-23 | -52.04 | amide transport | biological process | GO:0042886 | 1396 | 348 | 17256 | 2622 |
CCDC93,TMED7,RAB14,NUP188,PDCD6IP,TSC2,TAP1,AP3M2,SYNRG,RIC1,PARK7,RPL23A,CDK5,NAPG,SNUPN,RABGAP1L,RAB4A,SRSF4,AP1M1,DNM2,AP2B1,NUP153,SEH1L,SRP72,PGAP2,USO1,TMEM115,ATG9A,AKT2,MCL1,NUTF2,ICMT,MCFD2,RAB22A,RAB2B,ARF4,PLEKHF2,HHEX,SMAD2,TMED10,RPS27A,RPS14,EIF2D,VIPAS39,ATP6V0C,BTF3,RRS1,ARRB2,NMD3,ZMAT3,LONP2,AAAS,NXT2,GGA1,SEC61G,RAB23,ACAP1,TMED3,PSEN1,VPS25,COPG2,NPLOC4,COPB2,ATG4A,SNX18,FBXO7,TNPO3,ATP6V0A2,MVP,CPSF4,SYTL3,NUP85,TMED2,SRSF11,NAGPA,EIF5A,TIMM8B,GCC2,RPS10,RPS24,SSR2,SRSF5,MTX1,TOMM40,PTTG1IP,GOSR1,RHOB,DERL1,SEC31A,SCARB2,KPNA1,NSF,PPP3R1,SNX14,NUP58,EXOC3,ANKRD27,NDC1,SARNP,SYS1,RAB11B,RAF1,GPR89A,ANK3,VTI1A,C5orf30,MYH9,TBC1D13,AP1B1,STAM,RAB21,AHCTF1,TBC1D22A,TBC1D14,NUP107,TNPO2,TAP2,ZC3H3,ATP6V1G1,SNX8,SEC61B,GOPC,RNPS1,POLR2D,RPL38,SLBP,ATP6V0A1,RAB1A,AP4E1,ERC1,SERP1,PEX5,CHMP4A,HSPA4,SEC61A1,VPS26B,RAB24,RPLP1,SEL1L,PITRM1,RPS2,SCAMP3,SRSF6,TRAK1,BTN3A1,IFT27,RAB11A,JAKMIP1,RPL17,ARF5,RPL19,UPF2,MTX2,PPP3CA,GUK1,DENND1B,DENND4C,RPL8,RABIF,RAB3IP,DDX39A,MACF1,RPL27A,YIF1A,SLC19A1,KIF18A,HGS,RPL32,LTBP4,SLC38A7,STX18,PML,PSAP,YWHAH,GPR89B,IPO4,VPS29,SNAPIN,POLA2,MTX3,COPA,THOC1,SNX15,RBM8A,ALKBH5,UBE2Q1,AGFG1,RUFY1,SEC16A,SSR1,RAB8A,NUP210,RAP1A,TIMM23,EIF4A3,AP3S2,RAB35,ATG3,PIK3R2,RP2,TIMM50,CDC37,VPS13B,FYTTD1,LARS,TLK1,RAB5B,STX16,LSG1,OPTN,NECAP2,RPL37,TRAM2,TBC1D17,TIMM13,EIF4ENIF1,HSPB11,GRIPAP1,UEVLD,TIMM29,MIA2,ARRDC1,KPNA2,VPS4A,CLU,RPS26,ATP6V0E1,C2CD5,RPS15,TBC1D12,GORASP1,PHB2,CENPF,RPL15,RAB6A,XPO7,RHBDD1,NUP205,RINL,KIF13B,ARL6IP1,GLE1,LRSAM1,ATP6V0D1,PREB,KDELR1,ABCC1,RPL6,SYVN1,ZDHHC3,NPIPA1,RPL36,TSC1,GOLGA4,SNAP23,EXOC4,ZDHHC7,SIL1,NUP62,CTSA,CHMP2A,SNX27,CORO7,TOMM20,RPLP2,COPE,ATP6V1B2,LYN,RPAIN,BCAP31,RPL11,HNRNPA2B1,ATP6V0B,ANKLE1,SAR1A,AKAP8,BCAP29,SCAMP4,AHCYL1,CLTB,CHTOP,LMAN1,CHP1,SNX25,RPL29,NXT1,RPL35,PPT1,RAB7A,NUP155,BICD2,ERBIN,CHMP2B,RPS9,RHBDF2,RPSA,SRSF1,SURF4,VPS26C,TOMM6,TIMM17A,ARNTL,AP1S1,CHMP4B,SMURF1,AP2S1,ABCA1,PARD3,CDC40,GOLPH3L,RAE1,NUP54,VPS45,ARFIP2,TIMM21,ARF1,GGA2,AP3S1,TFRC,KLHL20,SEC24C,RRBP1,ARHGEF2,STAT3,CAMK2G,MYO5A,TGFB1,ZDHHC18,NASP,SNX2,SCFD2,COG1,SYMPK,MFN2,RAB18,SEC23IP,UPF1,ATP6V1D,PDCD6,KPNA4,GOLGA7,SNAP29,RBPJ,SPCS3,SRSF3,ATP6V1C1,CHMP7,RAB3IL1 |
| 2.965e-23 | -51.87 | GO_RNA_SPLICING_VIA_TRANSESTERIFICATION_REACTIONS | MSigDB lists | GO_RNA_SPLICING_VIA_TRANSESTERIFICATION_REACTIONS | 253 | 103 | 17377 | 2626 |
SART1,XAB2,SF3B1,RBM8A,DHX8,USP39,SNRPD3,PCBP1,PAPOLA,SF3B2,HNRNPA2B1,SNUPN,EIF4A3,METTL14,SRSF4,GPATCH1,TRA2B,AQR,RBM15,STRAP,CCAR1,PCBP2,SRSF10,CSTF1,SRPK2,PRPF19,CDC5L,SNRNP200,POLR2G,POLR2L,SNRPB,PPIE,CRNKL1,HNRNPF,POLR2D,RNPS1,DDX20,PRPF3,BUD13,TXNL4A,LUC7L,DHX15,CLNS1A,SRSF1,GEMIN5,SUGP1,HNRNPR,LSM6,DHX16,LUC7L3,PQBP1,PRPF4,SNRPG,SMNDC1,GEMIN7,PRPF4B,CDC40,ZCCHC8,POLR2K,SRSF6,DHX9,CDK13,PRPF39,PDCD7,METTL3,SRRT,PRPF18,RAVER2,GTF2F1,RBM17,SNRNP25,DNAJC8,CTNNBL1,CWC27,EFTUD2,BUD31,GEMIN6,YBX1,GEMIN4,PABPC1,HNRNPM,LUC7L2,SRSF11,YTHDC1,POLR2I,HELB,PSPC1,PPWD1,SRSF5,DDX39A,SF3A2,SNRPA,POLR2A,DDX23,SYNCRIP,POLR2J,RBMX,HNRNPH3,PRMT7,KHSRP,DDX5,SRSF3,SNRNP70 |
| 4.023e-23 | -51.57 | intracellular protein transport | biological process | GO:0006886 | 842 | 237 | 17256 | 2622 |
POLA2,TMED7,RAB14,NUP188,MTX3,TSC2,THOC1,COPA,RBM8A,SNX15,ALKBH5,AP3M2,AGFG1,SYNRG,RIC1,SSR1,RPL23A,CDK5,NAPG,RAB8A,SNUPN,NUP210,EIF4A3,TIMM23,AP3S2,RAB35,RABGAP1L,ATG3,RAB4A,SRSF4,AP1M1,AP2B1,NUP153,SEH1L,TIMM50,CDC37,SRP72,FYTTD1,LARS,USO1,AKT2,TLK1,NUTF2,ICMT,STX16,RAB5B,RAB22A,RAB2B,RPL37,HHEX,TBC1D17,TIMM13,TMED10,RPS27A,GRIPAP1,TIMM29,RPS14,EIF2D,MIA2,VIPAS39,KPNA2,CLU,VPS4A,RRS1,RPS26,NMD3,LONP2,C2CD5,AAAS,NXT2,TBC1D12,RPS15,GGA1,PHB2,SEC61G,RAB23,RPL15,RAB6A,TMED3,XPO7,VPS25,COPG2,RHBDD1,NUP205,NPLOC4,COPB2,ATG4A,KIF13B,FBXO7,ARL6IP1,TNPO3,GLE1,CPSF4,SYTL3,NUP85,TMED2,PREB,KDELR1,SRSF11,NAGPA,EIF5A,TIMM8B,GCC2,RPL6,RPS10,SSR2,RPS24,SYVN1,MTX1,SRSF5,TOMM40,PTTG1IP,ZDHHC3,RHOB,RPL36,DERL1,SEC31A,TSC1,SCARB2,KPNA1,NSF,EXOC4,PPP3R1,ZDHHC7,SIL1,NUP62,CTSA,NUP58,SNX27,NDC1,TOMM20,SARNP,RPLP2,RAB11B,VTI1A,TBC1D13,AP1B1,STAM,RPAIN,BCAP31,RPL11,HNRNPA2B1,ANKLE1,RAB21,SAR1A,TBC1D22A,TBC1D14,NUP107,TNPO2,BCAP29,LMAN1,CHTOP,AHCYL1,CLTB,ZC3H3,CHP1,SNX8,RPL29,SEC61B,RPL35,NXT1,RAB7A,RNPS1,POLR2D,RPL38,SLBP,NUP155,ERBIN,RAB1A,AP4E1,RPS9,RPSA,SRSF1,PEX5,HSPA4,CHMP4A,SURF4,VPS26C,SEC61A1,VPS26B,RAB24,TIMM17A,ARNTL,SEL1L,RPLP1,AP1S1,CHMP4B,SMURF1,PITRM1,AP2S1,PARD3,CDC40,RPS2,SRSF6,RAE1,TRAK1,NUP54,VPS45,ARFIP2,TIMM21,GGA2,AP3S1,IFT27,RAB11A,RPL17,SEC24C,ARHGEF2,RPL19,UPF2,STAT3,MTX2,TGFB1,ZDHHC18,PPP3CA,SNX2,RPL8,RAB3IP,DDX39A,RPL27A,SYMPK,MFN2,RAB18,SEC23IP,KPNA4,UPF1,HGS,PDCD6,RPL32,GOLGA7,STX18,PML,SRSF3,SPCS3,YWHAH,IPO4,VPS29,SNAPIN |
| 4.461e-23 | -51.46 | RPA3 (replication protein A3) | protein interactions | 6119 | 391 | 143 | 17029 | 2761 |
RAB14,HNRNPAB,ADD1,COPA,THOC1,YTHDF3,CUL1,EIF1B,RBM4,PABPC4,SF3B2,RAB8A,PCNA,RAB35,INTS1,AP2B1,KCNAB2,SEH1L,CDC5L,ERCC1,SNRNP200,VHL,SNRPB,HNRNPF,WDHD1,WDR82,SMC2,ESYT1,DIDO1,MCM2,RFC2,DHX15,PRIM1,GEMIN5,AHNAK,TIMM13,MAP4,U2SURP,PTPN7,ITGB1,ACTB,ZNF598,PARP12,EWSR1,PPP1R12A,ZCCHC8,DHPS,CHTF18,UBXN1,DHX9,RPL15,TOP2B,RAB6A,SMC3,EXOSC7,EIF2S2,ARPC5,EFTUD2,MSH2,CAPZA1,GEMIN4,ATP6V0D1,PABPC1,TERF2,NTPCR,PRRC2A,TEX10,RPL6,MPG,MATR3,XRCC5,EPRS,SYNCRIP,RBM25,RUVBL2,TCOF1,HNRNPDL,USP7,CHERP,RAB11B,SF3B1,CHD1L,TPX2,MYH9,AP1B1,BCAP31,HNRNPA2B1,STRBP,AKAP8,TARDBP,RBM15,RPRD1B,PRPF19,CDKN2AIP,RFC3,RAB7A,CUL3,DNAJC9,NFATC2,RAB1A,TRIM28,RPS9,SUPT16H,DDX17,PPP2CA,HNRNPR,FUS,TUBB,TMEM33,UNK,SCAMP3,TRIP12,EYA1,BLM,CSNK1A1,RMI1,TFRC,RPA2,RFWD3,ARHGEF2,LTN1,RPL19,TAGLN2,POLR1B,FBL,HNRNPM,SMC4,SPTAN1,PRKDC,ILF3,LDHA,TOP3A,SYMPK,PRDX1,ZFR,MYO1F,DDX23,RPA1,TFE3,BBX,PGRMC1,DDX5,DDB1 |
| 4.876e-23 | -51.38 | GSE36476_CTRL_VS_TSST_ACT_72H_MEMORY_CD4_TCELL_OLD_DN | MSigDB lists | GSE36476_CTRL_VS_TSST_ACT_72H_MEMORY_CD4_TCELL_OLD_DN | 188 | 85 | 17377 | 2626 |
TMEM106C,LYRM4,HNRNPAB,SUCLG1,FOXM1,GNPDA1,UCK2,TPX2,EBNA1BP2,NIT2,CLCC1,CCNB1,STMN1,FANCI,OIP5,SNUPN,CCNA2,IARS,GOT2,RNASEH2A,MKI67,PSMG1,RRM2,NUSAP1,CDC6,AURKB,SMC2,ICMT,MCM2,MRPS14,FANCE,SRSF1,RAD51C,CORO1C,CEP55,MLYCD,ATF6,TRIM32,RAD51D,TUBB,SEPHS2,MCM10,MUT,HJURP,CENPF,CDCA3,KIF23,RACGAP1,HAUS4,BLM,NCAPG,MYL6B,SPAG5,DTL,IRF4,SNRNP25,PSMD2,GART,MED8,MCM5,BDH1,TIMELESS,H2AFY,NAP1L4,CENPM,CYC1,MRPL11,ZNF189,TIMM8B,TK1,ASPM,METTL5,TEX10,FAM50B,COMMD4,KIF11,TARS,FADD,HMGN2,SLCO4A1,KEAP1,UBE2C,CCNB2,PGAM1,ESPL1 |
| 6.172e-23 | -51.14 | gag-pol (Gag-Pol) | protein interactions | 155348 | 714 | 219 | 17029 | 2761 |
HNRNPAB,COPA,ADAM10,RBM8A,MOGS,CSNK2A1,EBNA1BP2,SND1,CDIPT,OAT,UBE2I,MAP1LC3B,PABPC4,SF3B2,KRR1,PA2G4,RAB8A,PSMD1,EIF4A3,SRSF4,DNM2,SUCLG2,NUP153,NFU1,LRRC59,CARM1,SRSF10,CDC5L,SRP72,SP3,LARS,SNRNP200,VHL,HNRNPF,RRM2,MCL1,NUTF2,SLC25A5,DHX15,ARF4,EIF3A,IWS1,WAS,RAD18,PSMD8,KPNA2,ACTB,BTF3,RRS1,ARRB2,PSMC1,ZNF598,DDX58,RECQL,PHB2,DHX9,CTCF,TOP2B,CYCS,THRAP3,EIF2AK4,PSMD9,RPN1,MCM5,BANF1,BUD31,MSH2,TNPO3,YBX1,KIFAP3,BCL2,AHCY,ALDH18A1,ATP6V0D1,PABPC1,LUC7L2,EEF1D,EIF5A,EIF3L,TSTA3,ACSL3,RPL6,PSMA1,RPS24,PKM,MATR3,PSMB3,PSMC4,HMGN2,XRCC5,AKAP1,FAS,EPRS,KPNA1,SYNCRIP,NSF,RBMX,ACLY,NUP62,YWHAZ,ATP5F1A,YY1,PTDSS1,ZC3HAV1,CDKN2A,KCTD7,KARS,SART1,UBR2,MDH2,DYNLL1,SF3B1,EIF3D,SUMO2,MYH9,IRF3,C2orf49,PCBP1,STMN1,CPNE3,APP,HNRNPA2B1,FLAD1,PSMA6,IARS,PIN1,DUT,AKAP8,ANKRD13C,TARDBP,CLTB,PDIA6,CCT2,RPL29,RPL35,CGAS,RAB7A,IDH3A,KAT7,NARF,PSMB7,NUP155,NFATC2,BICD2,VDAC1,PSMB9,TRIM28,RPS9,EIF3G,EIF3H,SRSF1,DDX17,EIF3K,ATP1A1,SEC61A1,DDOST,HNRNPR,DHX16,SAFB,STK38,PSMD3,H2AFX,ANP32E,MAPK1,PRPF4B,NIFK,RPS2,PKP4,TKT,NKRF,HDGFL2,AP3S1,RAB11A,HLA-A,HDDC2,RPA2,PSMD2,DNAJC8,HUWE1,RPL17,ARF5,PELO,RPL19,HNRNPM,NUDC,RBM15B,SPTAN1,LDHB,AMPD2,STAU1,NASP,KAT2A,PRKDC,ZNF202,PARP4,TUFM,LDHA,RPL8,ILF3,ANAPC2,ARHGEF12,ZFR,PRDX1,HSPA1B,MAPK3,RPA1,DDX23,KPNA4,UPF1,PLAA,POLE,HNRNPH3,CDCA7L,LRPPRC,PML,KHSRP,DDX5,IPO4,SSSCA1 |
| 8.800e-23 | -50.78 | macromolecule biosynthetic process | biological process | GO:0009059 | 3729 | 762 | 17256 | 2622 |
ZBTB10,KDM4A,MRPS15,PIGQ,CCNL2,EDRF1,RBM4,ZNF275,PABPC4,EEF2K,RPL23A,USF1,CIPC,SRSF4,CRY2,ECD,ZNRD1,MGAT5,MRPL57,PGAP2,ZNF672,ZNF559,TMEM115,GABPA,MRPL43,WDHD1,MIER2,TOPORS,DIDO1,MCM2,GINS4,BRMS1,SMAD2,RPS27A,ZNF689,OGT,VIPAS39,ST3GAL2,TFDP2,SMAD1,E2F2,CHPF2,ZNF75A,SLC25A33,SSRP1,HIVEP3,MRPL9,CLSPN,MRPS2,DHX9,EZH1,CDC73,MCTS1,ATG4A,TFAP4,EIF2S2,INTS7,MCM5,EFTUD2,ZNF326,FOXN2,MRPL21,CPSF4,PABPC1,PHKG2,PPA1,CARS2,SRSF11,NAGPA,EIF3L,ETV3,FOXK1,RB1CC1,DHX29,ZMYND11,MAN1B1,RPS10,MYBL2,USP10,BCLAF1,MRPL16,SRSF5,CBFA2T2,ELK1,EIF4H,ABCF1,POLR2J,ETS2,SETD3,CNOT6,WIPI2,ZNF830,HEXA,SGF29,MRPL3,ZNF296,KARS,SARNP,TRERF1,IVNS1ABP,PTTG1,RMI2,CREBL2,RXYLT1,ZNF267,INO80E,EFL1,SAFB2,RCOR3,TCF19,ZNF420,SP100,ZKSCAN1,MTA1,DUT,GMEB1,NABP1,INTS12,ZNF226,ATF2,RPRD1B,CGGBP1,CPNE1,POLR2L,EID1,KAT7,INTS13,WBP2,RPL38,POLR2D,RNPS1,E2F3,NDUFA7,MEF2D,DDX17,TAF2,CHCHD3,HIPK2,RPLP1,RBMS1,SNRPG,PPP5C,ZBTB11,COMMD10,ZNF786,RPS2,ZNF445,SRSF6,HABP4,TRAK1,JMJD6,WDR5,ETS1,NEXMIF,ZNF92,RPA2,ZBTB45,GATC,SUV39H2,PPP1R8,PRDM4,ZNF260,LTN1,ST8SIA2,ZNF710,GTF2H2,RPL22L1,MED22,PDPK1,TK1,POLK,ZNF512,MRPS10,DDX39A,RPA1,ZNF180,ZNF862,KEAP1,MAGT1,POLE,PITX1,DBI,LRPPRC,PML,HMGB2,USF2,WDR45B,THAP5,AGRN,THOC1,GPBP1L1,RBM8A,CSNK2A1,SND1,BIRC2,PAPOLA,CREM,LIN9,TET3,PCNA,GLIS2,ZNF639,INTS1,ETV6,XRCC2,NOC2L,EIF5,MCMBP,MYBL1,MRPL32,CCAR1,ABCC5,RYBP,SP3,HARS,BAZ2A,RAD51AP1,SNRPB,MRPL12,CDC6,PBRM1,EAF2,BRCA1,KRTCAP2,USP21,ALG3,TONSL,CHD3,ZNF367,E2F4,QRSL1,DVL1,ZNF45,BEND6,FAM208A,POT1,ZNF564,FUBP1,ZCCHC9,PHB2,CENPF,SDC2,CTCF,CHCHD2,CDK13,B4GALT4,RLF,ASXL2,CNOT11,ARID1B,C1GALT1,SUB1,RB1,MLX,NUS1,MED8,MBD2,SSBP3,ZNF746,CTR9,TIMELESS,MDFIC,ICE2,MRPL48,MAML1,PREB,LDB1,UTP15,RTF1,ZNF761,LY6E,EIF4G2,ZDHHC3,NMT2,IRF5,ZNF174,RXRB,RPL36,GALNT2,PALB2,TBPL1,ZDHHC7,PRMT7,DTD1,RUVBL2,GLT8D1,CYLD,TRAF7,RPLP2,UGP2,ARID2,FOXM1,MRPL39,DYNLL1,XAB2,ZNF416,RRAGC,COMMD8,ZNF121,RPAIN,RPL11,MRPL50,NRF1,ZBTB21,ZNF473,KMT5C,ZNF302,MRPL34,RPAP1,TARDBP,LMAN1,TOP1MT,SAP30L,ZNF583,DVL2,KDM3B,RPL29,RPL35,POLR2G,ZNF780B,BTG2,NFATC2,KDM1B,MRPS14,EIF3H,RPSA,SRSF1,MRPL2,ZNF700,RBL1,MAFK,ZNF436,DNAJC17,XRCC3,NCOA1,SMAD4,RAD51D,INTS2,SLC30A9,CTDP1,NIFK,MCM10,CDC40,MTERF1,CDT1,AGO2,ARID5A,GTF3A,NKRF,PAGR1,RMI1,WRNIP1,IRF4,SS18L1,PTGES3,POLR1B,ORC3,RBM15B,CNTN5,RPRD1A,HMGN5,ZNF202,ZMYM5,TUFM,TOP3A,PCGF1,GOLGA7,BIRC5,L3MBTL3,TFE3,CDCA7L,BBX,E2F1,RBPJ,TAF12,NR2F2,HIPK3,IFI16,TXN,ZNF496,MAX,GXYLT1,ZDHHC8,CXXC1,GYG1,CCNB1,EIF1B,COMMD6,POLR3K,MYEF2,PA2G4,NOL11,FIZ1,ZNF200,TAF5L,DNMT1,ZNF800,CDC5L,ZNF524,KLF10,AKT2,ELOA,GALNT7,USP22,MCFD2,RFC2,CBFB,EIF3A,PRIM1,IWS1,HHEX,BRD2,STT3A,RPS14,MRPL27,EIF2D,BTF3,ARRB2,ZNF598,CCDC59,HDAC2,B4GALT2,PTOV1,EWSR1,DHPS,POLR2K,CHTF18,PRKAA1,GSPT2,RRM1,B4GALT1,NOTCH2,PMF1,SUPT7L,PSEN1,TMEM165,ZNF518A,ZNF79,VPS25,NPLOC4,CNOT3,YY1AP1,RPN1,LHX8,KLF16,HDAC7,DAD1,PIGG,MRPL40,EEF1D,TERF2,EIF5A,PHF10,ZNF84,PIGT,PRIM2,ELL2,NOA1,ZNF574,MFNG,RPS24,ARID1A,KDM3A,TWISTNB,PHF6,XRCC5,EPRS,ZNF777,SERTAD2,GOLGA2,ZFP92,RBMX,QARS,MED15,CEBPG,PIAS2,YY1,RNF14,CDK2,NRBP1,ZNF511,ATXN3,RWDD1,ZBTB37,SUZ12,EIF3D,SDE2,TERF2IP,SPINDOC,ZNF75D,KDM2A,UCHL5,LPIN2,MRPS27,RNASEH2A,CDK12,SAP30,BRD4,RFC3,ERF,DRAP1,SLBP,ELP4,EDF1,POLG2,GAR1,TRIM28,SERP1,CENPU,PRDM11,SUPT16H,EIF3K,VEZF1,RAD51C,ZNF282,MRPL55,DDOST,HINT1,SAFB,STAT1,FTSJ1,PPA2,ATF6,BEND3,B4GALT3,EYA2,ATMIN,POLQ,POU3F2,NCOR2,DEPDC1,TWNK,MECP2,B4GALT5,TCF3,SECISBP2,MYNN,ARGLU1,SDF2L1,BLM,POFUT1,FOXO3,HMG20A,MAD2L2,WWP2,GTF2F1,RFWD3,CCNK,RPL17,ELP5,FUT8,MRPL54,RPL19,CARF,CITED2,CREB1,OSTC,CNOT6L,NCOA2,TSHZ1,ZFP64,KAT2A,WDR18,ILF3,RPL8,RFXANK,RPL27A,COMMD4,KLF6,GUF1,POLR2A,CBX3,RPL32,ZHX1,TFDP1,KHSRP,DDX5,TAF6,CPEB2,PURA,RORB,CCNC,POLA2,ZNF76,PTMS,IER2,PIGM,KMT2E,PHRF1,MOGS,ZNF107,SIRT2,TAF6L,SNRPD3,COMMD5,MAPK14,SNAPC4,MRPL19,ZNF696,EIF4A3,JAZF1,PHTF1,ZBTB22,TCEA1,SLC35C2,ARID4A,CARM1,ELOF1,DEAF1,LARS,DPM1,RIOX2,RRM2,SOX4,KMT2C,ASF1B,CHAF1A,RPL37,MAN2A2,GEMIN5,UBTF,PAF1,BRWD1,IARS2,PQBP1,CRCP,BAZ1B,ZNF268,CHEK2,GALNT10,MRPL13,RPS26,RPS15,PIGN,GORASP1,ZNF768,NACA,MED13L,RPL15,MEF2A,THRAP3,TTF1,SRRT,LYAR,DTL,NFATC3,ZNF449,MED10,PYURF,BUD31,ZNF335,YBX1,ACAD8,ZNF189,VOPP1,POLR2I,CIC,RPL6,SYVN1,EIF2A,SLTM,DAPK3,ISG15,NAP1L1,NFIL3,NUP62,ZFP90,RBBP4,HNRNPDL,ADNP2,ZBTB24,TCF12,MBD1,ASH1L,MPHOSPH8,SMARCA4,PLAGL2,NSD3,IRF3,ORC1,EXT2,CHD1,MXD1,PAIP1,MEAF6,SAP130,FARSA,RRN3,IARS,CD3EAP,AKAP8,RPN2,CHTOP,UTP4,ZNF770,RLIM,CSTF1,POU2AF1,ZNF500,PCGF6,ATXN1,MBD3,EIF3G,RPS9,ZNF317,DAP3,STAT6,CHCHD1,ARNTL,CANT1,AKNA,MAPK1,BRD9,ABCA1,CBX4,PDF,NAT14,DNAJC2,MRPL42,ZNF316,EYA1,SCYL1,MRPS26,DBF4,KLF13,PAWR,MXD4,GFM2,MAN1A1,KMT5A,PELO,RRBP1,NABP2,ANP32A,BRD7,MRPL11,STAT3,SAMD4B,B3GALT6,GINS1,ZDHHC18,GTF3C6,NASP,PSPC1,HELB,MIER1,POLR3GL,RCOR1,MEN1,ZNF407,SYMPK,TARS,MAPK3,TFEB,CNOT9,UPF1,ATAD2,KMT2B,SRSF3,PLOD3,ZMIZ1,TERF1 |
| 1.033e-22 | -50.62 | SHEDDEN_LUNG_CANCER_POOR_SURVIVAL_A6 | MSigDB lists | SHEDDEN_LUNG_CANCER_POOR_SURVIVAL_A6 | 428 | 145 | 17377 | 2626 |
SRM,CCDC93,FGFR1OP,H2AFZ,KIF2C,CCNB1,MRPL19,FANCI,KRR1,CALM2,CDKN2C,PA2G4,PCNA,NUP210,EIF4A3,IMPAD1,AP2B1,MOB1A,TFG,MYBL1,TACC3,RPP25,NRAS,RAD51AP1,PBK,SNRPB,MRPL12,MKI67,GMFB,KIF15,RRM2,WDHD1,CDC6,AURKB,SMC2,RFC2,RAB22A,GINS4,PRIM1,KIF18B,PPM1G,KPNA2,MRPL13,CCDC59,PFKP,SMNDC1,HDAC2,RECQL,HJURP,CENPF,STRN4,KLC1,KIF23,RACGAP1,SPAG5,DTL,MED8,KLHL5,MCM5,KNTC1,PHF10,PRIM2,MYBL2,TOMM40,GNAS,MTHFD2,SYNCRIP,CDC27,DCK,SLC16A1,NUP62,RUVBL2,CCNB2,NUDT3,CDKN2A,FOXM1,WDYHV1,SLC2A1,PTTG1,ACTR3,TPX2,ORC1,STMN1,COMMD8,OIP5,CCNA2,SAR1A,KIF14,DDA1,PDCD2,SAP30,PPIF,ANKLE2,RFC3,PSRC1,DNAJC9,SLBP,NUSAP1,DNAJA1,SHCBP1,KIF2A,DSN1,RBL1,CEP55,H2AFX,XRCC3,AP2S1,CSNK1D,MIF,CMAS,MCM10,DEPDC1,MRPL42,CDT1,DBF4,CDCA3,CDCA8,SMC6,PAWR,NCAPG,FBXO5,PRC1,NAA50,GTSE1,CENPM,MSH6,LDHB,GINS1,TK1,ASPM,PRKDC,TBRG4,KIF11,KIF18A,ATAD2,BIRC5,TWSG1,NEIL3,TFDP1,PITX1,LRPPRC,HMGB2,WDR76,WDR62,UBE2C |
| 1.063e-22 | -50.60 | MORF_UBE2I | MSigDB lists | MORF_UBE2I | 230 | 96 | 17377 | 2626 |
SART1,KARS,NUP188,HNRNPAB,RPLP2,UBN1,RAF1,EIF3D,SUMO2,STARD7,DAZAP2,UBE2I,GNB2,PARK7,RPL11,HNRNPA2B1,RAB8A,CS,TARDBP,STRAP,PCBP2,CFL1,CCT2,SNRNP200,SEC61B,AATF,SNRPB,PSMB7,RNPS1,USP22,H2AFV,TRIM28,EIF3H,PPP2CA,EIF3K,DAP3,HSPB11,HINT1,BRD2,RPS27A,PSMD8,UQCRH,BTF3,COPS6,FAU,OAZ1,COX5B,MRPL9,PHB2,PDAP1,NACA,COX4I1,EBP,ERH,DNAJC8,HUWE1,RPL17,BANF1,YBX1,RPL19,RBM3,NAP1L4,CYC1,FBL,PABPC1,LYPLA2,HNRNPM,EEF1D,HMGN1,POLR2I,RHOA,RPL6,LDHA,JTB,ILF3,TUFM,RPS24,SSR2,DDX39A,EIF4H,EIF4G2,PSMB3,POLR2A,CBX3,XRCC5,GNAS,NAP1L1,HGS,CSK,RBMX,COX7A2L,COX8A,YWHAZ,SRSF3,SNRNP70,IDH3B |
| 1.100e-22 | -50.56 | regulation of catabolic process | biological process | GO:0009894 | 911 | 250 | 17256 | 2622 |
NUP188,TSC2,KDM4A,CSNK2A1,YTHDF3,SIRT2,UBQLN2,BECN1,MAPK14,RIC1,PARK7,TRIM65,FBXO22,PABPC4,CDK5,ABL2,RAB8A,PSMD1,NUP210,METTL14,PIK3R2,RAD23B,NUP153,CISD2,ECD,TIPARP,SENP1,DRAM2,SEH1L,MLST8,RYBP,CDC37,WDR41,PLK1,PLK3,LARS,TRIM8,EXOSC6,RBX1,AKT2,PBK,EZR,MCL1,ODC1,RHEB,OPTN,ABHD5,RPS27A,PSMD8,AXIN1,SOCS4,ITGB1,OGT,ADAM9,ATP6V0C,STK11,CHEK2,RNASEL,CLU,DVL1,ROCK1,PSMC1,OAZ1,ATP6V0E1,LONP2,AAAS,CAPN1,SVIP,TBC1D12,SCOC,GGA1,PHF23,UBXN1,PRKAA1,NKD2,DHX9,LAMTOR3,EIF2AK4,THRAP3,PSMD9,PARN,PSEN1,METTL3,NUP205,DDRGK1,DTL,EXOSC7,TIGAR,FBXO7,DAPK1,ATP6V0A2,BCL2,YBX1,PIKFYVE,LRSAM1,LPCAT1,ATP6V0D1,PABPC1,NUP85,PHKG2,SOCS5,ATP5IF1,RB1CC1,GBA,PIP4K2C,USP10,PSMA1,EXOSC9,ADRB2,PTTG1IP,FXR1,EIF4G2,DAPK3,PSMB3,RMC1,PSMC4,TSC1,HSPBP1,SYNCRIP,GOLGA2,NSF,LAMTOR4,EXOC4,FAM83D,NUP62,YWHAZ,CTSA,SNRNP70,RNF14,TOB1,RNF139,NUP58,ZC3HAV1,EGLN1,RNF114,USP7,NDC1,PRKAB1,ATXN3,FEZ2,SUMO2,RRAGC,ATP6V1B2,PRKACA,BCAP31,ANKIB1,EPM2A,PAIP1,RPL11,RAD23A,USP5,UBXN2A,ATP6V0B,PSMA6,MDM2,RALB,PIN1,TBC1D14,UCHL5,DDA1,EXOSC1,NUP107,CDKN1B,TARDBP,RNF19A,HTRA2,PDCL3,ATP6V1G1,UBQLN4,ULK3,TIMP2,POLR2G,PSMA8,RAB7A,BTG2,PSMB7,CIRBP,PFKFB3,ATP6V0A1,NUP155,EDEM2,VDAC1,PSMB9,USP36,CHMP4A,IDE,VPS26B,TAB2,HNRNPR,PSMD3,HIPK2,ARNTL,CHMP4B,TICAM1,SCARB1,TRIM32,SMURF1,CSNK1D,USP13,DAP,RAE1,AGO2,NUP54,SECISBP2,CSNK1A1,PIP4K2A,MAD2L2,WWP2,PPP1R3B,FASTKD3,PSMD2,PTEN,AXIN2,DCP1A,ANP32A,ATG13,CNOT6L,STAT3,TPCN1,RNF5,SAMD4B,LONRF3,TNFAIP3,TBRG4,PDE3B,SH3GLB1,MAPK3,MFN2,TFEB,HSPA1B,MTMR3,GNA12,KEAP1,ATP6V1D,UPF1,HGS,OAZ2,LRPPRC,E2F1,PML,KHSRP,PSAP,ATP6V1C1,WDR91,CD81,PGAM1,IFI16,DDB1,FAF1,VPS29 |
| 1.126e-22 | -50.54 | protein metabolic process | biological process | GO:0019538 | 4335 | 863 | 17256 | 2622 |
FGFR1OP,ADD1,KDM4A,MRPS15,MAP3K7CL,PIGQ,HEXB,XIAP,TGOLN2,RBM4,FBXO22,PABPC4,EEF2K,RPL23A,CDK5,PSMD1,NEK6,RAD23B,CRY2,NUP153,FNIP2,RNF26,TIPARP,ANKRD9,MGAT5,RHBDD2,SENP1,PCBP2,MRPL57,USP34,BAK1,PLK3,PGAP2,TMEM115,NRAS,EHMT1,MRPL43,MIER2,TOPORS,DCUN1D5,ICMT,ARF4,STOML2,BRMS1,SMAD2,RAD18,RPS27A,LIMK1,AXIN1,OGT,ATE1,VIPAS39,ST3GAL2,RNASEL,KLHL42,FBXL3,SMAD1,CHPF2,LONP2,AAAS,ZNF720,MRPL9,CLSPN,MRPS2,GGA1,TRIO,KCTD17,TOP2B,EZH1,EIF2AK4,ZNRF3,PSMD9,APH1B,CDC73,MCTS1,ATG4A,DDRGK1,PDXP,EIF2S2,RNFT1,FBXO7,EFTUD2,MRPL21,NUP85,PABPC1,PHKG2,PPA1,UBE2QL1,CARS2,NAGPA,EIF3L,FOXK1,MAPKAPK3,DHX29,MTA2,ERO1A,MAN1B1,RPS10,ARMT1,USP10,MRPL16,EIF4H,ABCF1,PTPRF,FNTA,DUSP3,CSK,SETD3,TEX30,PTAR1,WIPI2,CFAP20,HEXA,SGF29,RNF139,MRPL3,NUP58,EGLN1,TRIM41,KARS,ABCA3,UBR2,PTTG1,WDTC1,MYH9,RXYLT1,INO80E,EFL1,PRKACA,GLRX3,STAM,CPNE3,ANKIB1,KTN1,APP,PRKD3,FBXL6,MTA1,DDA1,UBA5,NUP107,NSFL1C,ANAPC7,RNF19A,MAVS,ATF2,CLN6,RPRD1B,RNF169,CPNE1,ULK3,SEC61B,ERMP1,KAT7,MAP4K4,RPL38,NDUFA7,RAB1A,FKBP3,PPP2CA,PEX5,CDC16,NSMCE2,HIPK2,CAMKMT,RNF38,RPLP1,DMWD,PPP5C,PITRM1,LRP8,USP13,RPS2,ZFP91,CCM2,TRAK1,JMJD6,UBE4A,WDR5,PPP1R3B,CAPN2,GOLM1,FBXO3,PSMD2,GATC,SUV39H2,HUWE1,PRDM4,NAA50,GTSE1,LTN1,KANSL2,UBE3B,TTLL12,ST8SIA2,GTF2H2,FBXL19,RPL22L1,LYPLA2,SPTAN1,PDPK1,PPP3CA,TNFAIP3,USP42,MRPS10,ZNF862,KEAP1,MAGT1,GPS2,DBI,MAPK6,CAPN7,PML,PARP10,WDR45B,ANAPC4,FAF1,SNAPIN,TRIM11,PPP1R15B,CSNK2A1,BIRC2,ZER1,TET3,FANCL,ABL2,RAB8A,PCNA,NUP210,EIF5,ASB6,MRPL32,RYBP,CDC37,PTPRK,PLK1,SP3,PTPN18,RBX1,HARS,BAZ2A,APH1A,SNRPB,TLK1,GMFB,MRPL12,UBE2V1,BRCA1,KRTCAP2,PRKRA,USP21,ALG3,TRIM4,CHD3,SOCS4,QRSL1,ADAM9,ARRDC1,ACTB,OSGEPL1,CLN3,NGLY1,NAA60,RMND5A,TMUB1,LAMTOR3,SDC2,ADCK5,CDK13,RAB6A,PPP3CB,B4GALT4,RLF,ASXL2,C1GALT1,NUS1,UBE2Q2,MED8,CCP110,PPIL2,CTR9,MDFIC,MRPL48,MAML1,LRSAM1,DCAF8,LDB1,KRAS,EIF2AK1,MAP4K3,RTF1,UBE4B,NFATC2IP,LY6E,METTL22,EIF4G2,ARMC8,STYXL1,ZDHHC3,NMT2,PSMC4,RPL36,MBIP,GALNT2,CDC27,ZDHHC7,PRMT7,RUVBL2,ECPAS,RNF114,USP7,KCTD7,CYLD,TRAF7,RPLP2,MRPL39,SUMO2,LYN,DUSP22,RAD23A,RPL11,SEC11A,MRPL50,PDK2,PSMA6,MDM2,KMT5C,BRPF3,ABRAXAS2,PIN1,PPME1,MRPL34,MINPP1,LMAN1,SAP30L,CTDSP2,SPSB3,PRPF19,KDM3B,PPIF,RPL29,RPL35,BIRC3,PPT1,PSMA8,RAB7A,BTG2,PPIE,MTMR6,NUP155,KDM1B,MRPS14,RHBDF2,EIF3H,RPSA,USP36,MRPL2,DNAJC10,IDE,CLK3,UBXN2B,FASTK,PSMD3,STK38,UHRF2,CHMP4B,NCOA1,H3F3A,LTA4H,AP2S1,USP53,SMAD4,ZC3HC1,CTDP1,KLHL21,AGO2,TMX3,CDCA8,SUMF1,CDK11B,GGA2,CSNK1A1,SCYL2,DNAJB9,PTPN2,HERC3,IRF4,CTSS,CWC27,CAMK2G,RNF5,CNTN5,RPRD1A,RHOA,PRKDC,TUFM,RANGAP1,PPWD1,PCGF1,PDCD6,FBXO41,NEK1,GOLGA7,BIRC5,USP20,SPCS3,TAF12,UBE2C,RPS6KC1,HIPK3,IFI16,GCSH,TXN,NUP188,PDCD6IP,GXYLT1,ADAM10,PRKCSH,ZDHHC8,CXXC1,CUL1,USP39,NHLRC3,CCNB1,UBE2I,EIF1B,PARK7,ASPHD2,AP2B1,FBXW2,TAF5L,MARCH2,CDC25B,MAST2,SEH1L,AKT2,PBK,LACTB,GALNT7,AURKB,USP22,CCNF,MCFD2,CBFB,EIF3A,DOT1L,MAP3K4,MKNK1,STT3A,PSMD8,RPS14,TPP2,MRPL27,EIF2D,PTPN7,PTPDC1,ARRB2,ZNF598,CCDC59,HDAC2,B4GALT2,DDX58,WSB2,PPIB,GMFG,DHPS,PRKAA1,GSPT2,B4GALT1,CYCS,MAN2B1,SUPT7L,PSEN1,TMEM165,VPS25,NPLOC4,WDR48,CFLAR,FKBP1A,RPN1,RNF121,KLHL5,ZNRF2,HDAC7,DAD1,PPP4R1,TPST1,DAPK1,PIGG,FBXL7,MRPL40,RNF135,EEF1D,APOL1,MORC3,SOCS5,EIF5A,PIGT,CPQ,COQ8A,NOA1,MFNG,USF3,RPS24,ADRB2,CYFIP2,KDM3A,MAP2K2,PSMB3,DERL1,CAT,EPRS,GOLGA2,EPOP,RBMX,CSNK1G1,QARS,DCAF11,PPP3R1,USP32,PIAS2,VCPIP1,YY1,MAP3K5,RNF14,CDK2,NRBP1,ZC3HAV1,NDC1,ATXN3,TP53RK,RWDD1,RAB11B,RPS6KA1,RAF1,SUZ12,EIF3D,RAC1,KLHL18,CRKL,APLP2,CCNA2,SHC1,KDM2A,SIAH1,MTMR4,UCHL5,SOCS6,MRPS27,TTC3,NAA35,ILKAP,CDK12,CFL1,SAP30,TAOK1,CUL3,ELP4,KIAA1586,PKMYT1,ASB13,CDC23,POLG2,PSMB9,ERC1,TRIM28,SERP1,SOCS7,AMZ2,EIF3K,ANKZF1,JAK1,MRPL55,DDOST,PPP2R5A,SEL1L,FTSJ1,PPA2,TRIM32,BEND3,B4GALT3,EYA2,CSNK1D,ADAM23,PRPF4B,OTUD5,B4GALT5,MECP2,MANBA,BABAM1,CDCA3,CBLL1,BRAP,SECISBP2,SDF2L1,RAB11A,POFUT1,WWP2,RFWD3,CCNK,RPL17,PTEN,FUT8,PTPN11,AXIN2,MRPL54,FEM1B,RPL19,COPS7B,MAP3K14,CREB1,OSTC,UBE2M,KAT2A,LONRF3,NEK7,ILF3,PARP4,RPL8,FBXO9,TBRG4,ANAPC2,OTUD3,RHOT1,ARSK,RPL27A,GUF1,MARK2,SPPL2B,FADD,FBXO21,NUCB1,SGSH,HGS,RPL32,PRDX3,TTLL4,PPP1R11,DUSP11,WDR91,CPEB2,ESPL1,DDB1,MIB2,ADA2,CCNC,PIGM,UBE2E2,NF1,DCAF15,KMT2E,MOGS,DNAJC24,UBE2Z,UBE2Q1,PTP4A3,TAF6L,SIRT2,UBQLN2,SNRPD3,FKBP2,USP48,BECN1,MAPK14,MRPL19,RNF103,UBLCP1,PCYOX1L,CDC42,ATG3,IMPAD1,SRI,JOSD1,NFU1,SLC35C2,ARID4A,FGFR1OP2,CARM1,TIMM50,SRPK2,COPS8,LARS,TRIM8,DPM1,NCK1,LAP3,VHL,RIOX2,WDR82,SUMF2,KMT2C,STK17B,RPL37,PAF1,GEMIN5,MAN2A2,UEVLD,PPM1G,IARS2,CAB39,BAZ1B,STK11,CHEK2,CLU,VPS4A,GALNT10,ROCK1,COPS6,MRPL13,RPS26,PSMC1,DCAF5,CAPN1,UBE2D3,RPS15,PIGN,PPP1R12A,GORASP1,UFC1,UBXN1,PCSK7,RPL15,MEF2A,PM20D2,XPNPEP3,TTF1,RHBDD1,NUP205,DTL,MED10,PYURF,ZNF335,TENM3,BCL2,YBX1,ZRANB1,UBE3C,CSNK1G3,ERLIN1,RPL6,PSMA1,EIF2A,SYVN1,VKORC1,DAPK3,ISG15,CAND1,MASTL,KLHL15,SIAH2,FN3KRP,NUP62,CTSA,RBBP4,NAA20,APOL2,PRKAB1,TOMM20,ASH1L,MPHOSPH8,WDYHV1,MDH2,NSD3,IRF3,EXT2,MEAF6,PAIP1,USP5,FARSA,UBXN2A,BABAM2,IARS,KIF14,PPP6C,PARL,RPN2,PDIA6,ABI1,SCYL3,HTRA2,RLIM,PGGT1B,RNF25,PCGF6,PSMB7,NLN,OGDH,EDEM2,PEF1,MBD3,TOLLIP,EIF3G,RPS9,BTBD1,DAP3,TAB2,CHCHD1,ARNTL,CANT1,FKBP5,USP11,SMURF1,MAPK1,PPP2R2D,TSPAN5,ABCA1,CBX4,PDF,SH2D3A,TRIP12,MRPL42,CASP6,SHPRH,EYA1,RAE1,SCYL1,SRGN,MRPS26,NUP54,PAWR,DCUN1D4,GFM2,MAN1A1,SPPL2A,FASTKD3,FGFR3,GRK2,KLHL20,KMT5A,PPIG,PELO,RRBP1,TANK,MRPL11,FBL,SLC35A1,TGFB1,B3GALT6,ZDHHC18,CSNK1G2,DCAF6,ADAM17,HEMK1,MIER1,PRKAR1B,RFFL,RCOR1,WDR81,PRMT2,MEN1,CDK11A,TARS,MAPK3,MTMR3,CTSL,PLAA,DTX4,KBTBD7,KMT2B,MBD6,PLOD3,PREPL,HRAS |
| 1.309e-22 | -50.39 | GO_CHROMOSOME | MSigDB lists | GO_CHROMOSOME | 824 | 231 | 17377 | 2626 |
POLA2,SKA3,H2AFZ,THOC1,KDM4A,CSNK2A1,SIRT2,KIF2C,CCNB1,UBE2I,BIRC2,PARK7,MIS12,MBD4,PCNA,XRCC2,PDS5B,KIF22,SMARCE1,DNMT1,SEH1L,CDC5L,PLK1,ERCC1,BAZ2A,GABPA,EHMT1,MKI67,WDR82,AURKB,BRCA1,SMC2,PBRM1,MCM2,RFC2,GINS4,ASF1B,CHAF1A,PRIM1,BRMS1,SMAD2,RAD18,TONSL,E2F4,OGT,BAZ1B,ACTB,CHEK2,RRS1,FAM208A,POT1,HDAC2,SSRP1,RECQL,NSMCE4A,PPP1R12A,HJURP,CHTF18,CENPF,CTCF,MEF2A,TOP2B,PMF1,PSEN1,CDC73,SPAG5,DTL,RB1,SMC3,INTS7,MCM5,MBD2,BANF1,XPA,BUD31,MSH2,TIMELESS,CTR9,KIFAP3,KNTC1,TNRC18,NUP85,TERF2,HP1BP3,ETV3,PRIM2,MTA2,ZMYND11,LDB1,MYBL2,EXOSC9,ARID1A,SEPT7,PHF6,XRCC5,HMGN2,SETD3,RBMX,CDCA5,RUVBL2,YY1,ZNF830,RBBP4,NDE1,CDK2,CDKN2A,TCF12,ZNF207,MBD1,ASH1L,DNMT3A,MPHOSPH8,UBR2,DYNLL1,SUZ12,MAGED1,SMARCA4,NUF2,INO80E,ORC1,MXD1,TERF2IP,PHC2,SAP130,OIP5,AHCTF1,SP100,CD3EAP,UCHL5,AKAP8,NUP107,NSFL1C,TARDBP,TOP1MT,ATF2,RNF169,HTRA2,DCTN1,PRPF19,BRD4,RFC3,HMGN4,WBP2,NUSAP1,CDCA2,DCLRE1C,MBD3,GAR1,H2AFV,POLG2,TRIM28,SUPT16H,PPP2CA,RAD51C,PPP2R5A,DSN1,STAT6,NSMCE2,STAT1,UHRF2,H2AFX,XRCC3,ANP32E,BEND3,NCOA1,H3F3A,XRCC4,SMAD4,RAD51D,PRPF4B,POLQ,NCOR2,MCM10,SHPRH,MECP2,TCF3,DCTN2,CDCA8,SMC6,HMGN3,BLM,CSNK1A1,NCAPG,WRNIP1,RFWD3,CAPN2,RPA2,IRF4,ADD3,SUV39H2,H2AFY,SS18L1,CENPM,PTGES3,CREB1,ORC3,CITED2,STAT3,MSH6,SMC4,GINS1,TELO2,HMGN1,NASP,HMGN5,KAT2A,HELB,PRKDC,TOP3A,POLR3GL,RANGAP1,WDR81,MEN1,ZFR,RPA1,CBX3,UPF1,KIF18A,POLE,BIRC5,ZNF330,LRPPRC,PML,E2F1,HMGB2,CENPT,MBD6,TERF1,PURA,DDB1,IPO4 |
| 1.347e-22 | -50.36 | chromosomal part | cellular component | GO:0044427 | 893 | 242 | 18223 | 2701 |
POLA2,MAX,SKA3,H2AFZ,THOC1,KMT2E,CSNK2A1,KIF2C,SIRT2,CCNB1,UBE2I,PARK7,MIS12,MBD4,USF1,PCNA,PARPBP,XRCC2,PDS5B,KIF22,MCMBP,SMARCE1,DNMT1,SEH1L,CDC5L,PLK1,ERCC1,BAZ2A,GABPA,RAD51AP1,WDHD1,WDR82,SMC2,PBRM1,AURKB,BRCA1,MCM2,RFC2,GINS4,ASF1B,PRIM1,CHAF1A,DOT1L,BRMS1,SMAD2,FBXO28,RAD18,TONSL,CHD3,E2F4,BAZ1B,ACTB,CHEK2,SLF1,SINHCAF,POT1,HDAC2,NSMCE4A,HJURP,PPP1R12A,CHTF18,CENPF,DHX9,CTCF,MEF2A,TOP2B,PMF1,ASXL2,PSEN1,CDC73,ARID1B,YY1AP1,SPAG5,RB1,SMC3,MCM5,MBD2,XPA,MSH2,BUD31,CTR9,TIMELESS,ICE2,KNTC1,TNRC18,NUP85,TERF2,HP1BP3,PHF10,ETV3,PRIM2,MTA2,LDB1,MYBL2,ARID1A,SEPT7,KDM3A,APPL1,PHF6,HMGN2,XRCC5,PAXX,NSMF,SETD3,RBMX,CDCA5,APPL2,RUVBL2,NDE1,YY1,RBBP4,CDK2,CDKN2A,SMARCD1,ZNF207,TCF12,CHMP2A,DNMT3A,MPHOSPH8,DYNLL1,SUZ12,UBR2,MAGED1,SMARCA4,NUF2,ORC1,INO80E,MEAF6,MXD1,PHC2,TERF2IP,HNRNPA2B1,OIP5,SAP130,AHCTF1,KMT5C,SP100,UCHL5,NUP107,NABP1,TARDBP,TOP1MT,ATF2,HTRA2,RNF169,DCTN1,PRPF19,KDM3B,RFC3,FAM172A,HMGN4,WBP2,NFATC2,DCLRE1C,MEF2D,KDM1B,H2AFV,MBD3,GAR1,TRIM28,CENPU,PPP2CA,RAD51C,DSN1,PPP2R5A,RBL1,NSMCE2,STAT6,H2AFX,UHRF2,STAT1,ANP32E,XRCC3,BEND3,NCOA1,H3F3A,SMAD4,RAD51D,DYNC1LI2,NCOR2,MCM10,SHPRH,MECP2,TCF3,CDT1,DCTN2,CDCA8,SMC6,PAWR,HMGN3,BLM,SPDL1,CSNK1A1,NCAPG,WRNIP1,RFWD3,RPA2,CAPN2,IRF4,SUV39H2,NABP2,H2AFY,SS18L1,CENPM,PTGES3,ORC3,CITED2,CREB1,STAT3,MSH6,SMC4,GINS1,TELO2,HMGN1,KAT2A,HMGN5,NASP,POLK,PRKDC,HELB,POLR3GL,RANGAP1,MEN1,CBX3,RPA1,LEMD2,KIF18A,UPF1,POLE,BIRC5,ZNF330,E2F1,PML,HMGB2,MBD6,CENPT,CHMP7,PURA,SLF2,TERF1,DDB1,IPO4 |
| 1.624e-22 | -50.17 | BORCZUK_MALIGNANT_MESOTHELIOMA_UP | MSigDB lists | BORCZUK_MALIGNANT_MESOTHELIOMA_UP | 289 | 111 | 17377 | 2626 |
TMED7,H2AFZ,COPA,RAF1,MAGED1,RAC1,TPX2,TMEM97,C5orf30,UBQLN2,CCNB1,PARK7,SSR1,PAPOLA,CDKN2C,RAP1A,PCNA,ATP2A2,RAB4A,TAF5L,RP2,MOB1A,CHTOP,F2R,SRSF10,SRPK2,SAP30,CCT2,RHOBTB3,NCK1,PPT1,PSMB7,GLO1,DNAJA1,BICD2,RAB1A,CCNF,VDAC1,RFC2,H2AFV,EIF3H,SRSF1,KRIT1,KIF2A,HSPA4,SMAD2,DDOST,PSMD8,FTSJ1,IARS2,KPNA2,AP2S1,SMAD4,SMNDC1,CSNK1D,WSB2,UBE2D3,MAPRE1,PPP1R2,SCAMP3,SEC61G,FZD6,PNO1,KIF5B,FKBP1A,PSMD2,H2AFY,AHCY,KIFAP3,PTGES3,FBL,STAT3,PABPC1,MSH6,SLC25A1,SMC4,GINS1,TGFB1,TK1,PRKDC,ZMYND11,JTB,RCOR1,RIT1,KIF11,RPA1,XRCC5,CBX3,MAGED2,SDHB,EPRS,PLD3,NAP1L1,SEC23IP,PDCD6,FNTA,CDC27,DCK,ERGIC3,PRPS2,CAPN7,DBI,TFDP1,PGRMC1,YWHAZ,TAF12,SRSF3,RBBP4,UBE2C,MRPL3,TERF1 |
| 1.667e-22 | -50.15 | HIST1H2BG (histone cluster 1 H2B family member g) | protein interactions | 8339 | 225 | 98 | 17029 | 2761 |
COX15,DNMT3A,MPHOSPH8,FOXM1,UBR2,FLYWCH2,SUZ12,CHD1L,TOR1AIP1,PMS2,TPX2,NSD3,KIF2C,USP48,SDHA,SDE2,PHC2,KIFC1,LIN9,BABAM2,CCNA2,KDM2A,RAD23B,KIF22,ZNF226,RNASEH2A,ARID4A,RNF169,RAD51AP1,KAT7,CUL3,SLBP,NUSAP1,CDCA2,AURKB,BRCA1,VDAC1,MCM2,ANLN,KDM1B,IWS1,BRD2,KIF18B,PPM1G,DNAJC17,CHMP4B,CCDC59,CBX4,PDCD4,ZC3HC1,PWWP2A,RECQL,C9orf78,CMAS,MCM10,TRIP12,PPP1R2,ZNF768,PDAP1,MECP2,ZFP91,CDCA8,KIF23,RACGAP1,RLF,METTL3,PPIL2,PRC1,PTPN11,TAGLN2,MORC3,TERF2,ZNF512,MIER1,NFATC2IP,MPG,CCDC71L,PCGF1,MEN1,EIF4H,ZNF174,PHF6,KIF18A,ATAD2,PALB2,CCDC86,BIRC5,L3MBTL3,PARG,BBX,CDCA5,YJU2,HMGB2,CENPT,WDR76,IGBP1,SGF29,ZBTB24 |
| 1.759e-22 | -50.09 | cell division | biological process | GO:0051301 | 480 | 157 | 17256 | 2622 |
SKA3,PDCD6IP,ENSA,USP39,CNTROB,KIF2C,SIRT2,CCNB1,UBE2I,BECN1,MIS12,KIFC1,CDK5,NEK6,RAB35,PDS5B,CDC25B,MCMBP,SEH1L,TACC3,PLK1,SEPT9,AATF,NSUN2,CDC6,SMC2,AURKB,CCNF,ANLN,EPB41,SEPT1,KIF18B,MAP4,CHEK2,VPS4A,KLHL42,ANXA11,NUMB,MAPRE1,RHOC,CENPF,CIB1,KIF23,HAUS4,RACGAP1,PMF1,HAUS2,SPAG5,RTKN,TMEM250,RB1,SMC3,ZNF449,SNX18,TIMELESS,FBXL7,KNTC1,GNAI2,SEPT8,SEPT7,RHOB,HAUS8,MASTL,GOLGA2,CDCA5,FAM83D,NDE1,ZNF830,CDK2,CCNB2,CABLES1,ZNF207,CHMP2A,ANK3,ACTR3,PTTG1,TPX2,MYH9,NUF2,STMN1,SDE2,OIP5,BABAM2,AHCTF1,CCNA2,ABRAXAS2,RALB,KIF14,SEPT11,ANAPC7,CABLES2,CEP63,CFL1,DCTN1,ANKLE2,MAPRE2,PSRC1,CDC123,INTS13,CUL3,NUSAP1,CDCA2,CDC23,CHMP2B,TXNL4A,KIF2A,CHMP4A,CDC16,DSN1,NSMCE2,CEP55,CHMP4B,REEP4,PPP2R2D,PARD3,ZC3HC1,TUBB,POU3F2,CTDP1,KLHL21,RAE1,CDT1,BABAM1,CDCA3,CDCA8,SPDL1,CSNK1A1,NCAPG,MAD2L2,SAPCD2,SAC3D1,FBXO5,CCNK,CENPJ,KMT5A,PELO,PRC1,ARHGEF2,MICAL3,SMC4,NUDC,RHOA,TACC1,ASPM,JTB,ANAPC2,KIF11,BORA,NEK1,BIRC5,CENPT,UBE2C,CHMP7,TERF1,ESPL1,ANAPC4,SSSCA1 |
| 2.534e-22 | -49.73 | HSIAO_HOUSEKEEPING_GENES | MSigDB lists | HSIAO_HOUSEKEEPING_GENES | 372 | 131 | 17377 | 2626 |
H2AFZ,TXN,COPA,AGPAT1,BECN1,SF3B2,EIF4A3,JOSD1,TCEA1,PCBP2,HNRNPF,EZR,ARHGDIB,SLC25A5,ARF4,BRD2,TMED10,RPS27A,PSMD8,RPS14,ITGB1,UQCRH,ACTB,CLU,COPS6,PSMC1,RPS26,OAZ1,ANXA11,UBE2D3,RPS15,NDUFV2,PHB2,DHPS,HLA-E,NACA,NDUFA4,COX4I1,PSEN1,FKBP1A,ATIC,BUD31,CAPZA1,ARL6IP1,YBX1,PABPC1,EEF1D,FTL,RPS10,RPL6,SSR2,BCLAF1,EIF4G2,EIF4H,PSMB3,FAS,HMGN2,GNAS,PFDN5,NAP1L1,FNTA,PDLIM1,QARS,MDH1,YWHAZ,SNRNP70,PTDSS1,KARS,RPLP2,DYNLL1,CAST,RAC1,MYH9,CHKB,DAZAP2,STMN1,BCAP31,RPL11,APLP2,RPN2,CTDSP2,CFL1,GPX4,RPL29,SEC61B,RPL35,POLR2L,BTG2,CIRBP,RPL38,VDAC2,TRIM28,RPS9,RPSA,HINT1,RPLP1,USP11,H3F3A,LTA4H,TUBB,NCOR2,RPS2,DCTN2,ARF1,AP3S1,HLA-A,RPA2,CAPN2,PSMD2,ERH,RPL17,RPL19,TAGLN2,FBL,STAT3,LDHB,RHOA,LDHA,RPL8,RPL27A,PRDX1,RPL32,GPS2,COX8A,DDX5,PSAP,PGAM1,YWHAH,CD81,UBE2C,DDB1 |
| 2.737e-22 | -49.65 | CCDC8 (coiled-coil domain containing 8) | protein interactions | 83987 | 551 | 180 | 17029 | 2761 |
RAB14,PDCD6IP,NUP188,COPA,NOP2,NF1,FAM129A,YTHDC2,TAP1,USP39,TAF6L,SND1,SEC16A,MAPK14,PABPC4,KIFC1,DST,PA2G4,PSMD1,RAB35,INTS1,NOC2L,TRA2B,RP2,LRRC59,CNNM3,PCBP2,TIMM50,LARS,SNRNP200,NSUN2,MKI67,HNRNPF,CKAP2L,AURKB,SMC2,MCM2,RFC2,LUC7L,EIF3A,STOML2,AHNAK,CHD3,RPS14,MAP4,ITGB1,BAZ1B,KPNA2,PSMC1,PFKP,HDAC2,ANXA11,EWSR1,NACA,PRKAA1,DHX9,XPO7,MYL6B,NUP205,LMNA,SMC3,ZNRF2,MCM5,EFTUD2,ZNF326,RTCB,MSH2,YBX1,GLE1,CPSF4,GNAI2,SLC12A2,PABPC1,RB1CC1,ACSL3,SUGP2,RPL6,PLEC,CAPZA2,PKM,FXR1,ABCF1,CCT8,MATR3,NCDN,XRCC5,CAND1,CAT,GNAS,EPRS,GALNT2,PCM1,SYNCRIP,NSF,QARS,RBMX,SNAP23,ACLY,RUVBL2,ATP5F1A,EHD4,NOP9,EXOC3,NDC1,SART1,IMMT,MDH2,SF3B1,EIF3D,TOR1AIP1,UCK2,ATP6V1B2,LYN,CPNE3,RPL11,ZBTB21,IARS,ATP2A2,AKAP8,RPAP1,ANAPC7,CHTOP,PDIA6,CCT2,RFC3,GOPC,NUP155,CDC23,RAB1A,TRIM28,DDX17,CHCHD3,AFDN,PEX5,ATP1A1,HSPA4,HNRNPR,PSMD3,STAT1,NCLN,PDCD11,RPS2,TRIP12,ANXA6,SCAMP3,FLOT1,PAWR,MYO9B,ATP5F1B,HEATR5B,HLA-A,PSMD2,GART,HUWE1,GTSE1,ARHGEF2,FBL,MYO5A,SMC4,STAU1,SNX2,BTAF1,PRKDC,ABCF2,LDHA,RPL8,ILF3,TUFM,MACF1,MARK2,POLR2A,ZFR,RPA1,UTP20,HNRNPH3,LRPPRC,PGRMC1,KHSRP,DDX5,YWHAH |
| 2.896e-22 | -49.59 | binding | molecular function | GO:0005488 | 14760 | 2420 | 17224 | 2647 |
ZBTB10,ABCC10,HEXB,TGOLN2,CCNL2,SYNRG,FBXO22,EEF2K,THAP4,RAD23B,ATP13A3,DNM2,ZNRD1,FTSJ3,USP34,CCDC57,ERCC1,NRAS,EHMT1,KIF15,HNRNPF,WDHD1,MIER2,DIDO1,MCM2,RAB22A,MID1IP1,SMAD2,RPS27A,MYO18A,OGT,COX5A,KLHL42,SMAD1,ZNF75A,ANXA11,ZNF720,GGA1,SEC61G,CCZ1,MUM1,TRIO,CUTA,RAB23,KCTD17,HAUS4,EIF2AK4,APH1B,PARN,CDC73,MYL6B,ATG4A,PDXP,SMC3,TNPO3,GEMIN4,MVP,NUP85,PABPC1,NSUN4,PPP6R1,PPA1,IFRD1,AGGF1,RBM42,FOXK1,GTPBP4,MAP7D1,MRPL16,ELK1,EIF4H,MAGED2,KPNA1,ETS2,TYW5,YJU2,WIPI2,RUFY3,PDLIM5,ACSF2,EXOC3,RHOG,VTI1A,C5orf30,STARD7,INO80E,RCOR3,LCLAT1,CPNE3,RBM23,AHCTF1,ZNF420,TBC1D22A,TBC1D14,GMEB1,NSFL1C,SEPT11,ZNF226,GPD1L,ZC3H3,ARL5A,PDCL3,SNX8,ERMP1,EID1,IDH3A,POLR2D,HTATIP2,MEF2D,TMEM147,GSTCD,MAT2A,VPS26B,CORO1C,NSMCE2,CAMKMT,PPP5C,PITRM1,TUBB,COMMD10,ZNF445,SRSF6,CCM2,HABP4,FLOT1,BTN3A1,ABHD14B,ATP5F1B,HDGFL2,TUT4,PPP1R3B,GOLM1,ZBTB45,HUWE1,ZNF260,NAA50,ANXA5,LTN1,KANSL2,NAP1L4,ST8SIA2,ZNF710,RPL22L1,MED22,SPTAN1,STAU1,TCTEX1D2,DDX24,TACC1,USP42,LDHA,HEBP2,LLPH,RAB3IP,PICALM,TTC33,SH3BP5,SLC19A1,PARG,ACOX1,FAM3C,AEN,PARP10,YWHAH,WDR45B,THAP5,GPATCH4,FAM129A,TRIM11,YTHDC2,RBM8A,SNX15,ENSA,NENF,SND1,RUFY1,TRIM65,PRNP,KRR1,RAB8A,NUP210,NT5DC1,NOC2L,EIF5,TACC3,RYBP,PTPN18,MIOS,SNRPB,MBLAC2,CDC6,PBRM1,UTP3,ODC1,USP21,TRAM2,FBXO28,GRIPAP1,ARRDC1,ADAM9,DVL1,NUMB,ZNF564,FUBP1,CTU2,PARP12,ZCCHC9,CENPF,LAMTOR3,CHCHD2,NCKAP1,LYRM2,RSAD1,TNS3,SUB1,RINL,MBD2,SSBP3,KIF13B,XPA,AHCY,RBM3,GLE1,MRPL48,LRSAM1,HDHD2,NTPCR,AMD1,CAMSAP1,ZNF761,ICAM2,METTL22,APPL1,BBS12,RXRB,SDHB,PCM1,GALNT2,NLRC5,RUVBL2,MYO9A,CCNB2,ECPAS,USP7,RPLP2,SUCLG1,ARID2,SLC2A1,ATP6V1B2,LYN,PCBP1,BCAP31,VAV1,PSMA6,ZNF473,KMT5C,BRPF3,ZNF302,TARDBP,SPIDR,CTDSP2,PRPF19,PPIF,KDM3B,MND1,CLCN3,BIRC3,RAB7A,PPIE,CHMP2B,VDAC1,TMEM201,EIF3H,GLOD4,IDE,DHX16,UHRF2,CHMP4B,XRCC3,CYBC1,PARD3,BCL2L12,NIFK,MCM10,MTERF1,KLHL21,PDAP1,TMX3,CDCA8,GTF3A,ARF1,CDK11B,PAGR1,TUBGCP2,DNAJB9,HOMER1,WBP1L,POLR1B,RNF5,RBM15B,PPAN,RHOA,RPRD1A,BTAF1,TOP3A,ARHGEF12,PCGF1,DDX23,RAB18,TRIM26,PDCD6,NEK1,ATP6V1D,FAM110A,L3MBTL3,NEIL3,CTBS,BBX,IMPDH1,TAF12,NR2F2,PGAM1,HIPK3,IFI16,TXN,PNISR,H2AFZ,TMEM203,PRKCSH,USP39,UBE2I,PARK7,GLMP,ASPHD2,ZNF428,RAB4A,TRA2B,SUCLG2,TAF5L,CISD2,SMARCE1,ZNF800,CDC5L,ZNF524,OSBP2,NSUN2,USP22,CLNS1A,EIF3A,ZMYM3,DOT1L,IWS1,ANKRD10,MKNK1,WAS,KIF18B,TPP2,C1orf109,ZMAT3,B4GALT2,PRPF38B,RECQL,C9orf78,EWSR1,GADD45G,RRM1,DNAAF5,ACAP1,B4GALT1,CYCS,SUPT7L,ZNF518A,WDR48,SPAG5,NPLOC4,CNOT3,RTKN,TMEM250,CEP104,EXOSC7,KLHL5,LRRC8D,PPP4R1,MSH2,OSTF1,MRPL40,TNRC18,SYTL3,APOL1,EIF5A,GCC2,PRIM2,ELL2,COQ8A,MFNG,USF3,RPS24,GORASP2,CAPZA2,ADRB2,MTR,CCT8,PHF6,PFDN5,GOLGA2,EPOP,RBMX,MED15,PIAS2,APPL2,CDKN2A,NUDT3,ZNF511,ATXN3,RAF1,KIAA0232,CD320,EPM2A,CCNA2,MTMR4,BRI3,TAP2,AQR,TP53BP2,RBM12B,CDK12,ILKAP,SAP30,BRD4,DRAP1,NARF,LRRC8A,ELP4,PKMYT1,ASB13,SERP1,TRIM28,SUPT16H,EIF3K,CHMP4A,CERS6,CBWD1,ATF6,XRCC4,ADAM23,PRPF4B,NDUFS1,DEPDC1,MECP2,SECISBP2,SPDL1,HMG20A,WWP2,JAKMIP1,CCNK,DNAJC8,ELP5,AXIN2,CARF,CITED2,JMJD4,KAT2A,TMEM126B,RABIF,PACS1,BMS1,KCNQ1,OTUD3,ARSK,MACF1,KLF6,COMMD4,KIF11,FADD,SH3GLB1,SMAP2,MYO1F,CBX3,INF2,TMEM127,PPP1R11,DUSP11,DDX5,WDR62,TAF6,ESPL1,PURA,DEF6,IPO4,FAM83G,DDB1,CCNC,NAT9,PTP4A3,UBE2Q1,BRIX1,ZNF696,SF3B2,CDC42,SYNM,GOT2,JAZF1,HADHB,RPF2,CNNM3,CARM1,SRPK2,WDR41,LARS,ZCCHC10,RIOX2,TMEM216,SUMF2,KMT2C,OGFR,PRPSAP1,ASF1B,RPL37,MAN2A2,EIF4ENIF1,NIP7,U2SURP,MIA2,ZNF268,VPS4A,PPP1R2,XPNPEP3,RGS2,LYAR,FAM89B,POLR2I,TRAFD1,SUGP2,GBA,SYVN1,EIF2A,DAPK3,ARHGAP15,MASTL,UAP1,NFIL3,YWHAZ,TMEM14A,TOB1,TSEN15,ADNP2,TCF12,PRKAB1,MDH2,SMARCA4,ORC1,RRN3,UBXN2A,IARS,CD3EAP,KIF14,EXOSC1,CS,CLTB,DNAL4,CSTF1,CHP1,POU2AF1,UBQLN4,PPP1R18,NXT1,HPDL,PGGT1B,SELPLG,SMU1,ATXN1,LSM8,GLO1,BICD2,OGDH,CADM1,EDEM2,HERPUD2,TOLLIP,FANCE,MBD3,RPS9,PDHX,ALKBH6,DUS3L,SURF4,ARNTL,ANP32E,FKBP5,ABCA1,GCLM,ZNF316,RAE1,DCTN2,NUP54,CHIC2,PAWR,MXD4,DCUN1D4,PIP4K2A,XPR1,FERMT3,KIF5B,KLHL20,SEC24C,RRBP1,DUS2,ARHGEF2,ANP32A,LDLRAD3,STAT3,MYO5A,AMPD2,NIPAL3,COA3,PHF20L1,DCAF6,FAM49B,ATP2C1,RFFL,COG1,RCOR1,PRMT2,TFEB,LEMD2,CTSL,UPF1,ELMO1,ZC3H7B,DTX4,ZMIZ1,HRAS,TERF1,SLF2,CCDC93,FGFR1OP,MAP3K7CL,AGPAT1,CNTROB,PPP1R16B,MIEN1,MIS12,CIPC,GSDMB,TTC9C,PDS5B,NUP153,SENP1,PGAP2,TMEM115,AATF,PLEKHM3,ARMH3,DCUN1D5,PLEKHF2,BRMS1,TRIM47,PWWP2B,WDR11,AXIN1,SMG9,TRIM52,LONP2,NDUFV2,PHF23,CERK,EZH1,ITGB5,LMNA,MCTS1,DDX56,EIF2S2,FOXN2,CARS2,C16orf72,RB1CC1,PRRC2A,ZMYND11,PGS1,MYBL2,ARMT1,UHRF1BP1,SRSF5,MPG,MATR3,CYB5A,NCDN,POLR2J,SETD3,CNOT6,NDE1,EGLN1,ZNF207,ANKRD27,PPP1R37,ABCA3,SARNP,IVNS1ABP,RMI2,TMEM97,MON1B,NUF2,ZNF267,EFL1,TCF19,KTN1,APP,CLUAP1,PRKD3,ATP2A2,UTP18,GRSF1,DUT,ZCCHC2,ANAPC7,FAM76B,RNF19A,CLN6,GCC1,RNF169,ATP6V1G1,ADCY7,ENPP4,RNPS1,FKBP3,DDX17,CHCHD3,PEX5,CDC16,HIPK2,NT5C3B,TICAM1,PDXK,NKAPD1,ZBTB11,TMBIM4,ANXA6,GMCL1,UBE4A,ETS1,PNO1,ZNF92,CAPN2,ADD3,SUV39H2,TTLL12,TPCN1,HNRNPM,LYPLA2,LDHB,PPP3CA,NUDT8,POLK,JTB,EMP3,MTMR12,ZP3,PDE3B,CIP2A,KIF18A,CCDC6,WNT5B,MAPK6,LY75,C4orf46,RGL1,PSAP,WDR76,IGBP1,FAF1,SNAPIN,AGRN,THOC1,GPBP1L1,GNPDA1,PPP1R15B,CSNK2A1,EBNA1BP2,BIRC2,GIT2,ATPAF1,ABL2,DLG5,XRCC2,ZFYVE27,MCMBP,PTPRK,CDC37,SP3,METTL1,EXOSC6,HARS,GMFB,ESYT1,ANLN,RAB5B,RHEB,DPYSL3,TBC1D17,CDCA4,TIMM13,TONSL,NRM,ACTB,ZNF45,SINHCAF,C2CD5,TMUB1,CTCF,DOCK11,ASXL2,CRLF3,LRRC14,NUS1,SLC27A4,MDFIC,AFF1,MAML1,CYTH1,NQO2,UTP15,EIF2AK1,EIF4G2,ITPRIPL1,CDC27,SNAP23,TBPL1,PRMT7,ATP5F1A,KCTD7,NDUFA5,CYLD,UGP2,FAM207A,DYNLL1,COPE,ZADH2,GGPS1,RPAIN,ABRACL,RAD23A,PDK2,ZBTB21,STRBP,TNFAIP8,DUS4L,PDCD2,SAP30L,CLPTM1,RPL29,TIMP2,RPL35,BTG2,TUBGCP5,DNAJC9,MTMR6,NFATC2,KDM1B,ARL5B,USP36,MRPL2,ATP1A1,CLK3,MAFK,PSMD3,CEP55,PLGRKT,ZNF436,DNAJC17,NCOA1,ZC3HC1,ZNF146,SMAP1,CDC40,DAP,GNE,SMC6,ARFIP2,NKRF,BZW2,WRNIP1,SS18L1,PTGES3,CAMK2G,MLEC,ZNF202,FAM50B,RHOT2,NEU1,TPD52L2,GOLGA7,TWSG1,PGRMC1,GLG1,FAM126A,GUCD1,RPS6KC1,UBE2C,CCNB1,COMMD6,POLR3K,RIC1,UTP25,SNUPN,ASAP2,CNPY4,TFG,PLCL2,SPTSSA,SEH1L,ATG9A,PBK,ARHGAP45,MKI67,DDX20,GALNT7,AMDHD2,CCNF,RBM47,PTER,WDR4,DHTKD1,SARAF,TRAF5,HDAC2,PWWP2A,HSPH1,MAPRE1,CHTF18,ADO,KIF23,PMF1,NOTCH2,JMY,FKBP1A,SLC31A1,SNX18,ATIC,CTPS1,ATP6V0A2,RNF135,PIKFYVE,LPCAT1,EEF1D,TMED2,PHF10,FTL,DDX28,ZNF84,SIGMAR1,PIP4K2C,FAM133B,PLEC,RIT1,CYFIP2,KDM3A,SF3A2,FAS,EPRS,ZNF777,CSNK1G1,QARS,DCAF11,PPP3R1,TCOF1,NRBP1,CABLES1,DNMT3A,CKLF,RWDD1,TRIP10,RPS6KA1,SF3B1,CAST,SUZ12,RAC1,OLA1,SNN,GNB2,SDE2,FLAD1,APLP2,KDM2A,CDKN1B,TNPO2,TALDO1,GPX4,ATP13A1,RFC3,MAPRE2,ERF,TAOK1,CUL3,SLBP,POLG2,PSMB9,H2AFV,GAR1,DHX57,CENPU,SOCS7,NSA2,HSPA4,JAK1,TBL3,FAAP100,H2AFX,SEL1L,KLHDC4,B4GALT3,PDCD11,CSNK1D,ATMIN,POLQ,POU3F2,NCOR2,PKP4,SCAMP3,TWNK,BABAM1,CDCA3,SLC25A12,BLM,TMCC3,GTF2F1,RPL17,CRAT,AHSA1,PRC1,UPF2,COPS7B,CNOT6L,CNPY3,IFT46,UBE2M,TSHZ1,ZFP64,STRIP1,DENND1B,DENND4C,TRIR,WDR18,ILF3,RPL8,RHOT1,MARK2,TSR2,ECH1,PRDX1,POLR2A,FBXO21,NUCB1,GNA12,PLD3,C1orf131,PFDN4,PRDX3,HNRNPH3,STX18,TFDP1,NAXE,KHSRP,ASNA1,CPEB2,SSSCA1,BYSL,VPS29,S100PBP,DDX52,MIB2,ADA2,IER2,NOP2,UBN1,DCAF15,NF1,FLYWCH2,ALKBH5,UBE2Z,TAF6L,MAPK14,BECN1,SNAPC4,RNF103,MBD4,CYREN,CMSS1,METTL14,ZNHIT6,IMPAD1,RCSD1,PHTF1,SRI,KHDC4,KIF22,ZBTB22,NFU1,OGG1,TRIM14,ELOF1,COPS8,FYTTD1,TRIM8,RRM2,SOX4,PAF1,CXXC4,UBTF,SPATA2,ATXN2L,PQBP1,IARS2,GALNT10,ROCK1,STARD3NL,RPS15,AGTRAP,CDIP1,CIB1,XPO7,SRRT,ZNF449,CAPZA1,KIFAP3,BCL2,GLTP,N4BP2,HP1BP3,ISG15,CAND1,GNAS,TSC1,RBM25,CDCA5,ZFP90,RBBP4,NIPSNAP2,HNRNPDL,ZBTB24,SMARCD1,WASF2,MBD1,MMACHC,TOMM20,FAM92A,MPHOSPH8,GNPNAT1,HNRNPUL2,NSD3,CHD1,MEAF6,MIEF1,BABAM2,CCDC50,AKAP8,PARL,RPN2,CHTOP,F2R,ABI1,SCYL3,TMEM14C,HTRA2,RLIM,FAM172A,ZNF500,PSMB7,NLN,WIPF1,BOLA1,ERBIN,BUD13,PEF1,EIF3G,BTBD1,TAB2,TULP3,CHCHD1,WDR59,CANT1,SCARB1,GAS2,USP11,SMURF1,PPP2R2D,TSPAN5,MAGEH1,MRPL42,EYA1,CDK2AP2,MRPS26,LETMD1,KLF13,HDDC2,RGS1,MAN1A1,FBXO5,GART,PELO,TANK,BRD7,MRPL11,SAMD4B,GTF3C6,POLR3GL,WDR81,MEN1,ZNF407,MFN2,COX8A,ZRANB2,SRSF3,MBD6,ATP6V1C1,TATDN1,IDH3B,TSC2,LACTB2,CMTM6,RBM4,ZNF275,RPL23A,CDKN2C,NAPG,USF1,DNAAF2,AP1M1,UPRT,CRY2,ECD,MOB1A,RNF26,LRRC59,TIPARP,BAK1,RHOBTB3,ZNF559,GABPA,WBP1,NUTF2,ARF4,GINS4,KRIT1,AHNAK,RAD18,PDRG1,RNASEL,OAZ1,SMNDC1,PDCD4,NXT2,HIVEP3,CLSPN,RHOC,DHX9,PSMD9,HAUS2,COPB2,CD59,TFAP4,RNFT1,MEGF8,RIMS3,RBM34,FBXO7,EFTUD2,MYDGF,CPSF4,MRPL21,PHKG2,LUC7L2,SRSF11,EIF3L,MAPKAPK3,MTA2,MTFR2,SF3B6,TYW1,ERO1A,ITM2A,SSR2,USP10,BCLAF1,FNTA,PDLIM1,TXNDC16,CFAP20,ZNF830,TMEM159,MRPL3,NUP58,ALS2,FAM72A,KARS,TRIM41,NQO1,POC1A,ANK3,PTTG1,TPX2,TBC1D13,DAZAP2,GLRX3,STMN1,CBWD5,REPS1,ABHD16A,SH3BP1,MTA1,UBA5,CLCN6,NABP1,INTS12,MICU2,RPRD1B,CGGBP1,CPNE1,ULK3,SEC61B,POLR2L,FAM118B,GOPC,KAT7,CIRBP,E2F3,RPL38,CRNKL1,PFKFB3,GORAB,RAB1A,GIGYF1,KIF2A,PPP2CA,ALDH3B1,LSM6,CCDC14,RNF38,CENPBD1,SNRPG,USP13,MZT1,ZFP91,TRMT6,IP6K2,WDR5,PMVK,IFT27,NEIL2,SAPCD2,RRP36,SRXN1,RPA2,PSMD2,PDCD10,CLIC4,CBWD2,COQ4,ITGB8,ARF5,ARHGEF1,FBXL19,GTF2H2,UTP20,MAGT1,GPS2,DBI,SSNA1,MRFAP1L1,CD81,AAMDC,WDR13,FANCI,PAPOLA,CREM,TET3,FANCL,GLIS2,TIMM23,IL6ST,POP7,MTPN,ASB6,PLK1,RPP25,CELSR2,SEPT9,RBX1,APH1A,RAD51AP1,ZBED5,PSMG1,UBE2V1,EAF2,IL12RB1,LUC7L,LSG1,ALG3,TRIM4,CHD3,E2F4,ZNF367,KPNA2,PRPF4,BEND6,CLN3,FAM208A,NGLY1,POT1,MYL12B,CCDC137,RMND5A,HJURP,PHB2,DNAJB2,FAM53C,NKD2,SDC2,KLC1,COX4I1,CDK13,ADCK5,DNAJB1,RAB6A,CNOT11,ARID1B,C1GALT1,MLX,UBE2Q2,CCP110,ZNF746,ARL6IP1,CTR9,ICE2,NIPSNAP1,ABHD2,DCAF8,ACSL3,LDB1,MAP4K3,ARMC8,RBM38,IRF5,RPL36,HAUS8,PAXX,MBIP,LAMTOR4,SIL1,FAM122A,DTD1,UNC13C,BCCIP,SART1,TRAF7,TOR1AIP1,ZNF416,LAGE3,ZFYVE21,RRAGC,ZNF121,OIP5,NRF1,ABRAXAS2,PPME1,PIN1,EFCAB11,RPAP1,AHCYL1,TOP1MT,LMAN1,STRAP,SPSB3,ZNF583,SNX25,ARHGAP17,POLR2G,ZNF780B,KIAA0040,PPT1,NUP155,DCLRE1C,MRPS14,RHBDF2,SUGP1,AFDN,RBL1,UBXN2B,STK38,FASTK,AP1S1,H3F3A,SLC22A23,CHID1,SMAD4,RAD51D,SLC30A9,UNK,NADSYN1,AGO2,HMGN3,NCAPG,SCYL2,FZD6,GTPBP3,CTSS,ORC3,RNLS,YTHDC1,HMGN5,CSRP1,PRKDC,METTL5,ABCF2,TUFM,RANGAP1,PNPLA8,HAGH,API5,ZFR,SEC23IP,E2F1,USP20,RBPJ,PDCD6IP,MAX,ADAM10,TSC22D3,CXXC1,CUL1,GYG1,OAT,MYEF2,ANKRD26,MTFR1L,PA2G4,NOL11,FIZ1,ZNF200,AP2B1,FBXW2,MARCH2,SRSF10,SRP72,KLF10,LACTB,SUPT20H,CBFB,RFC2,RAB2B,PRIM1,MAP3K4,HHEX,BRD2,LUC7L3,RPS14,MAP4,MRPL27,BTF3,SLF1,NMD3,CCDC59,COX5B,SCOC,DHPS,POLR2K,C16orf87,VAV2,PRKAA1,GSPT2,TATDN3,DLGAP4,PXMP2,PRPF39,PSEN1,ZNF79,PDXDC1,VPS25,NDUFS7,YY1AP1,FAM192A,RPN1,LHX8,ARPC5,ZNRF2,TPST1,DAPK1,PIK3IP1,CYC1,MRM3,FDFT1,SOCS5,GID8,PIGT,CPQ,WDR1,ZNF574,C1orf35,EXOSC9,ARID1A,FXR1,PTTG1IP,GOSR1,MAP2K2,AKAP1,HMGN2,XRCC5,PI4K2A,DERL1,CAT,SEC31A,MTHFD2,HSPBP1,CEBP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|
| 3.007e-22 | -49.56 | macromolecule localization | biological process | GO:0033036 | 2248 | 502 | 17256 | 2622 |
CCDC93,TMED7,RAB14,TXN,NUP188,PDCD6IP,TSC2,HEXB,TAP1,AP3M2,SYNRG,RIC1,PARK7,MIS12,RPL23A,CDK5,NAPG,SNUPN,RABGAP1L,RAB4A,SRSF4,AP1M1,DNM2,AP2B1,NUP153,RNF26,SEH1L,SRP72,PGAP2,USO1,TMEM115,OSBP2,ATG9A,AKT2,NOL8,MRNIP,MCL1,TOPORS,NUTF2,AURKB,ICMT,MCFD2,RAB22A,RAB2B,ARF4,PLEKHF2,STOML2,IWS1,HHEX,MID1IP1,SMAD2,TMED10,RPS27A,RPS14,EIF2D,VIPAS39,ATP6V0C,BTF3,RRS1,ARRB2,SLF1,NMD3,LONP2,ZMAT3,AAAS,DDX42,NXT2,MAPRE1,GGA1,SEC61G,CUTA,DHX9,RAB23,ACAP1,TMED3,SUPT7L,PSEN1,VPS25,COPG2,LMNA,SPAG5,NPLOC4,COPB2,ATG4A,RTKN,TMEM250,SNX18,FBXO7,TNPO3,ATP6V0A2,PIKFYVE,MVP,CPSF4,SYTL3,NUP85,TMED2,APOL1,MORC3,TERF2,SRSF11,NAGPA,EIF5A,TIMM8B,GCC2,SIGMAR1,RPS10,RPS24,SEPT8,SSR2,SRSF5,MTX1,TOMM40,PTTG1IP,GOSR1,RHOB,XRCC5,DERL1,SEC31A,EPRS,SCARB2,OSBPL11,FNTA,KPNA1,NSF,FAM83D,PPP3R1,WIPI2,YY1,SGF29,SNX14,NUP58,ALS2,EXOC3,ANKRD27,NDC1,ABCA3,SARNP,ATXN3,SYS1,RAB11B,RAF1,GPR89A,ANK3,C5orf30,VTI1A,STARD7,MYH9,TBC1D13,AP1B1,STAM,MOAP1,TERF2IP,RAB21,AHCTF1,SP100,TBC1D22A,TBC1D14,NUP107,SEPT11,TNPO2,TAP2,ANKRD13C,ZC3H3,ARL5A,ATP6V1G1,SNX8,CCT2,SEC61B,GOPC,INTS13,WBP2,RPL38,POLR2D,RNPS1,SLBP,ATP6V0A1,DNAJA1,RAB1A,AP4E1,ERC1,SERP1,PEX5,CHMP4A,HSPA4,SEC61A1,VPS26B,RAB24,CCDC14,CORO1C,RPLP1,SEL1L,PITRM1,CSNK1D,RPS2,MZT1,SCAMP3,SRSF6,MECP2,FLOT1,TRAK1,BTN3A1,SPDL1,IFT27,RAB11A,WRB,HEATR5B,JAKMIP1,RPA2,RPL17,ARF5,AXIN2,DCP1A,RPL19,UPF2,MTX2,PACS2,NCOA2,PPP3CA,TNFAIP3,GUK1,DENND1B,DENND4C,RPL8,RABIF,PACS1,RAB3IP,DDX39A,MACF1,RPL27A,SH3GLB1,RPA1,YIF1A,KIF18A,KEAP1,HGS,RPL32,STX18,LRPPRC,PML,KHSRP,SSNA1,PSAP,CD81,YWHAH,WDR45B,VPS29,FAF1,IPO4,GPR89B,ESYT2,SNAPIN,POLA2,MTX3,AGRN,THOC1,COPA,RBM8A,SNX15,ALKBH5,UBE2Q1,AGFG1,RUFY1,BECN1,SEC16A,SSR1,DLG5,RAB8A,NUP210,RAP1A,GOT2,TIMM23,EIF4A3,AP3S2,RAB35,ZNHIT6,ATG3,PIK3R2,SRI,ZFYVE27,RPF2,RP2,CARM1,TIMM50,PTPRK,CDC37,VPS13B,PLK1,FYTTD1,LARS,SEPT9,MIOS,TLK1,EZR,PITPNB,ESYT1,ANLN,STX16,RAB5B,LSG1,OPTN,NECAP2,RPL37,PAF1,TRAM2,SEPT1,TBC1D17,HSPB11,EIF4ENIF1,TIMM13,TONSL,GRIPAP1,UEVLD,TIMM29,MIA2,ARRDC1,KPNA2,CLU,DVL1,VPS4A,ROCK1,RPS26,POT1,ATP6V0E1,C2CD5,TBC1D12,RPS15,GORASP1,PHB2,CENPF,NKD2,LAMTOR3,CTCF,TIA1,RPL15,RAB6A,XPO7,RAPGEF6,RHBDD1,NUP205,PRPF18,CHKA,RB1,RINL,KIF13B,XPA,PPIL2,ARL6IP1,SLC27A4,KIFAP3,GLTP,YBX1,GLE1,MCPH1,LRSAM1,ATP6V0D1,PREB,ABCC1,KDELR1,ACSL3,RPL6,SYVN1,SEPT7,ZDHHC3,NPIPA1,RPL36,TSC1,GOLGA4,PCM1,SNAP23,LAMTOR4,ODF2,EXOC4,ZDHHC7,SIL1,NUP62,CTSA,PITPNA,RUVBL2,APOL2,SNX27,CHMP2A,CORO7,TOMM20,RPLP2,TOR1AIP1,COPE,RRAGC,ATP6V1B2,LYN,TWF2,BCAP31,RPAIN,RPL11,HNRNPA2B1,ANKLE1,ATP6V0B,MDM2,SAR1A,KIF14,AKAP8,BCAP29,SCAMP4,LMAN1,CHTOP,CLTB,AHCYL1,GM2A,DVL2,PRPF19,CHP1,SNX25,RPL29,RPL35,NXT1,PPT1,RAB7A,TOR1AIP2,NUP155,BICD2,ERBIN,CHMP2B,ARL5B,TOLLIP,RPS9,RHBDF2,RPSA,SRSF1,SURF4,VPS26C,TULP3,TOMM6,TIMM17A,ARNTL,CEP55,AP1S1,CHMP4B,SCARB1,NCOA1,SMURF1,AP2S1,ABCA1,TSPAN5,PARD3,TMEM33,CDC40,GOLPH3L,KLHL21,RAE1,SRGN,DCTN2,VPS45,NUP54,ARFIP2,TIMM21,ARF1,GGA2,AP3S1,TFRC,KIF5B,KLHL20,SEC24C,RRBP1,NABP2,H2AFY,ARHGEF2,ATG13,ABCD1,FBL,STAT3,CAMK2G,MYO5A,TGFB1,ZDHHC18,NASP,SNX2,SCFD2,COG1,RANGAP1,PNPLA8,SYMPK,MFN2,LEMD2,RAB18,SEC23IP,KPNA4,PDCD6,UPF1,ATP6V1D,GOLGA7,OSBPL8,SNAP29,FAM126A,PKD2,RBPJ,SRSF3,SPCS3,CENPT,ATP6V1C1,PLOD3,CHMP7,SLF2,RAB3IL1 |
| 3.019e-22 | -49.55 | GO_NUCLEOLUS | MSigDB lists | GO_NUCLEOLUS | 795 | 224 | 17377 | 2626 |
DDX47,NOP2,KDM4A,NF1,SNX15,EBNA1BP2,BRIX1,CUTC,RBM4,POLR3K,UBLCP1,RPL23A,KRR1,PA2G4,RAB8A,NOL11,JAZF1,ETV6,POP7,PHTF1,NOC2L,RPF2,NUP153,TCEA1,ZNRD1,FTSJ3,SRPK2,CDC5L,NOL12,PLK3,SRP72,PLK1,METTL1,DEAF1,USO1,EXOSC6,AATF,BAZ2A,NOL8,NSUN2,MKI67,EZR,SMC2,UTP3,MAK16,DHX15,EIF3A,CHAF1A,UBTF,TIMM13,BRWD1,CHD3,SPATA2,NIP7,RPS27A,RPS14,RRS1,RPS26,NMD3,ZMAT3,SSRP1,CCDC137,TMUB1,ZCCHC9,EWSR1,HJURP,POLR2K,DHX9,CTCF,TOP2B,DNAJB1,RGS2,PARN,TTF1,VPS25,DTL,LYAR,SUB1,DDX56,NFATC3,EXOSC7,VMP1,RBM34,TIMELESS,MDFIC,RBM3,GEMIN4,MRPL40,EEF1D,EIF3L,DDX28,POLR2I,OXR1,TEX10,RPS10,UTP15,GTPBP4,RTF1,EXOSC9,BCLAF1,SRSF5,SEPT7,FXR1,TWISTNB,PHF6,XRCC5,RPL36,MBIP,CCDC86,ZDHHC7,PRMT7,TCOF1,BTBD10,TSEN15,CDKN2A,ZNF207,TRIM41,MPHOSPH8,URB2,SUZ12,OLA1,SMARCA4,INO80E,ORC1,RPAIN,MEAF6,RPL11,RRN3,MDM2,SP100,KDM2A,NVL,CD3EAP,UTP18,EXOSC1,AKAP8,TTC3,TOP1MT,CHTOP,CDK12,SAP30L,ACSL5,CDKN2AIP,RPL35,POLR2L,KAT7,CIRBP,NUSAP1,GORAB,EDF1,GAR1,RPS9,USP36,DDX17,KIF2A,NSA2,VEZF1,HNRNPR,DGCR8,LSM6,TBL3,TULP3,CHCHD1,STAT1,BEND3,PDCD11,COIL,ZNF146,MIF4GD,RPS2,MCM10,RRP15,RAE1,MRI1,ARID5A,CDCA8,JMJD6,ABHD14B,NKRF,BLM,RRP36,DNAJB9,PNO1,KRI1,H2AFY,DDX31,RPL19,POLR1B,FBL,HNRNPM,TMX1,RBM15B,PPAN,HMGN5,DDX24,PSPC1,PRKDC,ILF3,RPL8,BMS1,LLPH,PRMT2,SNRPA,POLR2A,DDX23,UTP20,ZNF330,ACOX1,CDCA7L,PITX1,PML,PGRMC1,AEN,HMGB2,DDX5,ASNA1,RBPJ,MBD6,PARP10,TERF1,IFI16,BYSL,SNAPIN,DDX52 |
| 3.036e-22 | -49.55 | GGGCGGR_V$SP1_Q6 | MSigDB lists | GGGCGGR_V$SP1_Q6 | 2741 | 587 | 17377 | 2626 |
ADD1,XIAP,AGPAT1,CNTROB,SYNRG,PABPC4,EEF2K,CALM2,CDKN2C,USF1,PSMD1,NSRP1,SRSF4,RAD23B,MECR,PDS5B,DNM2,UPRT,CRY2,NUP153,RHBDD2,SENP1,FTSJ3,PCBP2,NRAS,MRPL43,HNRNPF,TOPORS,NUTF2,SLC50A1,RAB22A,GINS4,AHNAK,SMAD2,MYO18A,OGT,COX5A,ATP6V0C,ST3GAL2,DDX42,NXT2,PHF23,GGA1,SEC61G,DHX9,MYL6B,DDRGK1,MCTS1,TFAP4,EIF2S2,INTS7,NSUN4,PABPC1,LUC7L2,C16orf72,PRRC2A,MAN1B1,MTX1,ELK1,MATR3,MAGED2,FNTA,DUSP3,WIPI2,RNF139,ALS2,RHOG,ZNF296,TRIM41,ANKRD27,GGNBP2,SARNP,TRERF1,IVNS1ABP,POC1A,WDTC1,STARD7,CREBL2,DAZAP2,PRKACA,STMN1,REPS1,KTN1,ARL6IP6,ABHD16A,AHCTF1,SH3BP1,UTP18,DDA1,CEP63,FAM76B,ATF2,GPD1L,GCC1,CGGBP1,PDCL3,CPNE1,KAT7,IDH3A,E2F3,CIRBP,POLR2D,PFKFB3,NUSAP1,GORAB,DNAJA1,MEF2D,RAB1A,FKBP3,MAT2A,CHCHD3,PEX5,VPS26B,CORO1C,RNF38,RBMS1,ZBTB11,ZFP91,HABP4,FLOT1,JMJD6,AKT1S1,IP6K2,PMVK,FBXO3,PPP1R3B,PDCD10,ITGB8,ARF5,DCP1A,ST8SIA2,ZNF710,FBXL19,TPCN1,SPTAN1,TTPAL,DDX24,ZNF512,EMP3,C14orf132,RAB3IP,DDX39A,PICALM,RPA1,SH3BP5,KEAP1,GPS2,CCDC6,CAPN7,MAPK6,RGL1,FAF1,SNAPIN,WDR13,FAM129A,ENSA,CSNK2A1,CDIPT,SSR1,ZER1,RAB8A,IL6ST,PIK3R2,NOC2L,EIF5,CDC37,PLK1,SP3,MIOS,BAZ2A,RBX1,APH1A,MBLAC2,LNX2,CKAP2L,BRCA1,EAF2,ESYT1,PRKRA,KRTCAP2,ANLN,STX16,USP21,EPB41,OPTN,C1orf122,TBC1D17,AGPAT2,GRIPAP1,ZNF367,NRM,BCL7C,RMND5A,TMUB1,DNAJB2,CTCF,PPP3CB,RAB6A,RAPGEF6,VASP,MLX,NUS1,VMP1,MEA1,TIMELESS,CTR9,AHCY,MDFIC,LRSAM1,ABHD2,DCAF8,LDB1,MAP4K3,EIF2AK1,UBE4B,EIF4G2,APPL1,PSMC4,RXRB,MOSPD3,PCM1,ITPRIPL1,SYNCRIP,ORMDL2,PRPS2,TBPL1,ZDHHC7,MYO9A,BTBD10,TIGD2,SART1,NDUFA5,CYLD,UGP2,XAB2,DYNLL1,SUMO2,SLC2A1,LAGE3,TM9SF3,RRAGC,ZFYVE21,HCFC1R1,ZADH2,BCAP31,OIP5,VAV1,SEC11A,NRF1,ATP6V0B,TNFAIP8,WDR44,CORO1A,LMAN1,DVL2,SPSB3,POLR2G,SLC26A6,PRPF3,MRPS14,SUGP1,MRPL2,FASTK,ZNF436,AP1S1,XRCC3,SLC25A39,ATXN7L2,CDC40,ARFIP2,ARF1,AP3S1,BZW2,PTPN2,GTPBP3,HOMER1,ABCD1,RNF5,RBM15B,YTHDC1,RHOA,PNPLA8,PCGF1,TPD52L2,KPNA4,TFE3,NEIL3,E2F1,PGRMC1,IMPDH1,NR2F2,CHMP7,H2AFZ,TXN,ZNF496,ADAM10,TSC22D3,OAT,EIF1B,PA2G4,FIZ1,CNPY4,SLC26A2,CDC25B,MAST2,PRADC1,SMARCE1,ZNF800,NOL12,ZNF524,KLF10,AKT2,ZFAND5,CBFB,SLC25A5,RAB2B,IWS1,HHEX,BRD2,TMED10,TPP2,PTER,RPS14,LUC7L3,MAP4,ITGB1,ARRB2,RTN3,B4GALT2,PTOV1,HSPH1,MAPRE1,CHTF18,ADO,RRM1,DLGAP4,MAN2B1,PMF1,PSEN1,PDXDC1,WDR48,CNOT3,RTKN,RNF121,SLC31A1,ARPC5,BDH1,PCYT2,PIKFYVE,GNAI2,ANKHD1,TMED2,FDFT1,EIF5A,ELL2,MFNG,PLEC,TOMM40,KDM3A,MTR,PSMB3,XRCC5,HMGN2,ADSS,GOLGA2,TMEM54,ERGIC3,ACLY,ARAP1,USP32,SAMD8,YY1,CDK2,DNMT3A,REPS2,TRIP10,RAB11B,ZBTB37,EIF3D,ADPGK,BCL2L1,AP1B1,GNB2,PAIP2,APLP2,SHC1,KDM2A,MTMR4,RALB,UCHL5,TNPO2,CDKN1B,CFL1,SAP30,GPX4,CCT2,ERF,DRAP1,VDAC2,ABHD11,H2AFV,TRIM28,ERC1,EML4,SUPT16H,VEZF1,ZNF282,HSPA4,PPP2R5A,DDOST,SAFB,RHEBL1,ADAM23,OTUD5,POU3F2,MECP2,SLC41A1,MANBA,MRI1,CDCA3,FAM76A,CBLL1,BLM,RAB11A,FOXO3,HMG20A,POFUT1,FUT8,AXIN2,PRC1,UPF2,TAGLN2,OSTC,CREB1,CITED2,CNPY3,NCOA2,SMC4,PDLIM2,KAT2A,LONRF3,NET1,ILF3,RPL8,COMMD4,MARK2,SMAP2,POLR2A,ECH1,TMEM127,GNA12,OAZ2,KHSRP,DDX5,BRWD3,TAF6,PURA,DDB1,DEF6,VPS29,RORB,PTMS,HNRNPAB,TMEM184B,FLYWCH2,MOGS,UBE2Z,ABCB10,KIF2C,SIRT2,TAF6L,FKBP2,UBQLN2,ATG3,DPYSL2,RAB35,SIVA1,PHTF1,JOSD1,ZBTB22,CNNM3,OGG1,FGFR1OP2,ARID4A,TRIM14,TRIM8,CCDC138,SOX4,GEMIN5,RPL37,MAN2A2,PAF1,UBTF,ATXN2L,PQBP1,SH3GLB2,COPS6,ATP6V0E1,STARD3NL,UBE2D3,PPP1R12A,ZCCHC8,UBXN1,CIB1,EPN1,CHKA,YBX1,KIFAP3,SLC12A2,POLR2I,OXR1,PSMA1,THNSL1,CAND1,ODF2,SLC16A1,NUP62,YWHAZ,RBBP4,ADNP2,TCF12,WASF2,SNX27,FEZ2,MPHOSPH8,PLAGL2,ORC1,USP5,SAP130,SAR1A,CD3EAP,AKAP8,CS,SCAMP4,PDIA6,SCYL3,DNAL4,HTRA2,MOSPD1,EBAG9,NXT1,PSMB7,ATXN1,GLO1,CADM1,OGDH,HERPUD2,PON2,DAP3,TAB2,HNRNPR,TULP3,ARNTL,FKBP5,REEP4,ABCA1,SHPRH,SCYL1,KLF13,DCUN1D4,PIP4K2A,XPR1,FERMT3,SEC24C,PPIG,RRBP1,ANP32A,CLDND1,TTC17,LDLRAD3,FBL,C12orf75,SLC25A1,B3GALT6,TGFB1,ADAM17,HMGN1,NASP,PPP1R21,MIER1,WDR81,SYMPK,TFEB,LEMD2,MTMR3,ZNF330,MBD6 |
| 3.836e-22 | -49.31 | KOBAYASHI_EGFR_SIGNALING_24HR_DN | MSigDB lists | KOBAYASHI_EGFR_SIGNALING_24HR_DN | 241 | 98 | 17377 | 2626 |
SRM,POLA2,H2AFZ,CKLF,UCK2,TPX2,KIF2C,SLC29A1,ORC1,CCNB1,SLC20A1,POLR3K,FANCI,PA2G4,PCNA,CCNA2,DUT,KIF14,RNASEH2A,MYBL1,PLK1,PPIF,PSRC1,RFC3,RAD51AP1,PBK,MKI67,KIF15,POLR2D,RRM2,DNAJC9,NUSAP1,CDC6,AURKB,BRCA1,SMC2,PKMYT1,CCNF,MCM2,SHCBP1,RFC2,ODC1,ASF1B,RAD54B,CHAF1A,PRIM1,CDCA4,DSN1,KIF18B,CEP55,H2AFX,KPNA2,GALNT10,TUBB,MCM10,DEPDC1,RRP15,HJURP,CDT1,DBF4,CDCA8,RRM1,CDCA3,KIF23,RACGAP1,BLM,NCAPG,RMI1,SPAG5,RFWD3,DTL,MCM5,MSH2,PRC1,TIMELESS,GTSE1,CENPM,MSH6,SMC4,GINS1,TK1,ELL2,ASPM,MYBL2,RANGAP1,DDX39A,KIF11,SLCO4A1,ATAD2,BIRC5,TFDP1,E2F1,HMGB2,TCOF1,CDK2,UBE2C,ESPL1,ZC3HAV1 |
| 3.952e-22 | -49.28 | GRADE_COLON_AND_RECTAL_CANCER_UP | MSigDB lists | GRADE_COLON_AND_RECTAL_CANCER_UP | 272 | 106 | 17377 | 2626 |
USP7,KARS,SKA3,H2AFZ,OLA1,TMEM97,RMI2,DHX8,NIT2,POMP,CCNB1,HNRNPA2B1,PA2G4,PCNA,CDC25B,ECD,TALDO1,MLST8,RLIM,CSTF1,SRP72,PLK1,COPS8,MKLN1,DPM1,SNRPB,NOL8,PSMB7,POLR2D,PSMG1,RRM2,NUSAP1,CDC6,GLO1,MCM2,RFC2,RHEB,SRSF1,DAP3,HSPA4,NIP7,NSMCE2,PDXK,TRAF5,LRP8,PDCD2L,SSRP1,POLQ,DNAJC2,MRPL9,HJURP,TKT,RRM1,DHX9,CHCHD2,KIF23,GTF3A,ITGB5,METTL3,POFUT1,RTKN,LYAR,EIF2S2,CBWD2,INTS7,MCM5,ATIC,EFTUD2,TIMELESS,GEMIN6,H2AFY,ANXA5,AHCY,KNTC1,FBL,SLC12A2,PPA1,LDHB,FDFT1,TTPAL,ZNF84,NQO2,PRKDC,METTL5,CAMSAP1,LDHA,PSMA1,LY6E,BORA,DDX39A,ABCF1,CCT8,TARS,PSMB3,PRDX1,MAGED2,EPRS,MTHFD2,PDCD6,SYNCRIP,ETS2,HMGB2,SMPD4,PTDSS1,MRPL3,GCSH |
| 4.098e-22 | -49.25 | MORF_HDAC1 | MSigDB lists | MORF_HDAC1 | 245 | 99 | 17377 | 2626 |
POLA2,CHMP2A,KARS,H2AFZ,HNRNPAB,CHERP,DYNLL1,EIF3D,SUMO2,COPE,STARD7,AP1B1,SDHA,GNB2,PARK7,RAD23A,SF3B2,CALM2,HNRNPA2B1,RAB8A,DUT,CS,HADHB,TRA2B,TARDBP,TCEA1,PDIA6,CDC37,CCT2,SNRNP200,BAZ2A,CDC123,EID1,TLK1,PPIE,VDAC2,PSMB7,RNPS1,NDUFA7,H2AFV,EIF3G,TRIM28,EIF3H,EIF3K,HSPB11,DDOST,HNRNPR,PPM1G,UQCRH,BTF3,COPS6,HDAC2,NDUFV2,COX5B,MRPL9,SCAMP3,PHB2,NACA,COX4I1,XPO7,AP3S1,NDUFS4,ERH,RPN1,NDUFV1,DNAJC8,CAPZA1,H2AFY,ANP32A,PTGES3,CYC1,HNRNPM,IFRD1,HMGN1,NSDHL,WDR1,JTB,ILF3,TUFM,FBXO9,DDX39A,EIF4H,SF3A2,SNRPA,CBX3,XRCC5,SDHB,CSK,TATDN2,SETD3,RBMX,ACLY,IMPDH1,HMGB2,MDH1,YWHAZ,SRSF3,NDUFS5,RBBP4 |
| 4.121e-22 | -49.24 | DNA metabolic process | biological process | GO:0006259 | 788 | 223 | 17256 | 2622 |
POLA2,PTMS,THOC1,KMT2E,ALKBH5,UBE2I,PARK7,FANCI,MBD4,LIN9,FANCL,TET3,PCNA,CYREN,PARPBP,XRCC2,RAD23B,PDS5B,KIF22,CRY2,TCEA1,MCMBP,DNMT1,OGG1,CDC5L,COPS8,TDP1,ERCC1,EXOSC6,RBX1,BAZ2A,RAD51AP1,EHMT1,MRNIP,WDHD1,RRM2,CDC6,UBE2V1,BRCA1,MCM2,RFC2,GINS4,PRIM1,CHAF1A,DOT1L,RAD18,TONSL,RPS27A,MYO18A,KPNA2,CHEK2,COPS6,SLF1,POT1,SSRP1,UBE2D3,RECQL,NSMCE4A,CLSPN,POLR2K,CHTF18,MUM1,CENPF,DHX9,RRM1,TATDN3,CIB1,TOP2B,RLF,NPLOC4,JMY,WDR48,DTL,SMC3,MCM5,MBD2,XPA,MSH2,TIMELESS,TERF2,POLR2I,PRIM2,MTA2,USP10,MPG,ISG15,XRCC5,GNAS,PAXX,NAP1L1,KPNA1,PALB2,POLR2J,CDCA5,PRMT7,DTD1,RUVBL2,YY1,ZNF830,RBBP4,CDK2,BCCIP,USP7,MBD1,ATXN3,DNMT3A,FOXM1,UBR2,XAB2,SUMO2,CHD1L,PTTG1,PMS2,RMI2,INO80E,ORC1,RPAIN,SDE2,RAD23A,TERF2IP,ANKLE1,BABAM2,SP100,KDM2A,MTA1,DUT,UCHL5,NABP1,RNASEH2A,AQR,TOP1MT,SPIDR,PRPF19,MND1,RFC3,POLR2G,POLR2L,BTG2,KAT7,TAOK1,PPIE,POLR2D,SLBP,DCLRE1C,KDM1B,POLG2,MBD3,FANCE,GAR1,TRIM28,RAD54B,SUPT16H,RAD51C,FAAP100,NSMCE2,H2AFX,UHRF2,RBMS1,XRCC3,BEND3,PPP5C,GEN1,XRCC4,EYA2,RAD51D,POLQ,SLC30A9,DNAJC2,MCM10,TRIP12,SHPRH,EYA1,TWNK,TCF3,CDT1,BABAM1,DBF4,SMC6,BLM,PAGR1,RMI1,MAD2L2,NEXMIF,NEIL2,WRNIP1,RBM17,RFWD3,RPA2,HUWE1,NABP2,AXIN2,COPS7B,PTGES3,ORC3,ERI3,GTF2H2,MSH6,GINS1,TELO2,HEMK1,TK1,HMGN1,NASP,POLK,PRKDC,HELB,WDR18,TOP3A,PARP4,MEN1,POLR2A,RPA1,UPF1,POLE,TATDN2,NEIL3,HMGB2,RBPJ,TATDN1,TERF1,PURA,SLF2,DDB1 |
| 4.202e-22 | -49.22 | VCP (valosin containing protein) | protein interactions | 7415 | 609 | 193 | 17029 | 2761 |
RAB14,ST13,ADD1,NF1,CUL1,TAF6L,CCNB1,SEC16A,COMMD6,KCMF1,FANCI,RNF103,PIK3R2,CRY2,TTC4,CDC37,PLK1,TDP1,ATG9A,LRBA,WDR82,BRCA1,MCM2,TMED10,ITGB1,CAB39,PRPF4,ACTB,CHEK2,ARRB2,NGLY1,PSMC1,NMD3,PDCD4,SVIP,GGA1,UBXN1,PRKAA1,PDXDC1,CDC73,RHBDD1,NUP205,NPLOC4,LMNA,LYAR,RPN1,ZNF326,TNPO3,ALDH18A1,ANKHD1,PHKG2,TERF2,ABCC1,NIPSNAP1,SRSF11,EIF5A,COQ8A,RPL6,PSMA1,USP10,BCLAF1,UBE4B,PLEC,ADRB2,SYVN1,PKM,CCT8,APPL1,ISG15,NCDN,PSMC4,DERL1,CDC27,NSF,CSK,DCAF11,VCPIP1,NUP62,YWHAZ,RUVBL2,RBBP4,CDK2,NIPSNAP2,NUP58,ALS2,BCCIP,ATXN3,CYLD,RAB11B,WDYHV1,RAF1,RPS6KA1,SUZ12,SUMO2,COPE,AP1B1,STMN1,RAD23A,RBM23,UBXN2A,CLUAP1,MDM2,PSMA6,UBA5,NUP107,PPP6C,NSFL1C,CDKN1B,TARDBP,ANAPC7,RPN2,RNF19A,LMAN1,CLN6,HTRA2,PRPF19,ANKLE2,KDM3B,CCT2,CDKN2AIP,ULK3,ARHGAP17,PPP1R18,RFC3,PPT1,RAB7A,CUL3,ATXN1,H2AFV,RPS9,SUPT16H,ANKZF1,PPP2CA,DNAJC10,DAP3,HSPA4,UBXN2B,CEP55,STAT1,CHMP4B,FUS,NCOA1,MAPK1,SMURF1,COIL,TUBB,TMEM33,USP13,ANKRD13D,GOLPH3L,TRIP12,TKT,NUP54,UBE4A,GGA2,BLM,BZW2,TUBGCP2,HLA-A,PNO1,DNAJB9,WRNIP1,RPA2,PDCD10,CTNNBL1,HUWE1,RRBP1,ARHGEF2,ANXA5,PTGES3,UBE2M,SPTAN1,TELO2,PPP3CA,NASP,SYMPK,MARK2,CIP2A,POLR2A,ZFR,MAPK3,CNOT9,HLA-B,INF2,TPD52L2,PDCD6,PLAA,HNRNPH3,SRSF3,YWHAH,ESPL1,FAF1,IPO4 |
| 5.136e-22 | -49.02 | BLALOCK_ALZHEIMERS_DISEASE_DN | MSigDB lists | BLALOCK_ALZHEIMERS_DISEASE_DN | 1177 | 300 | 17377 | 2626 |
TXN,MRPS15,HEXB,CUL1,GLUD1,OAT,EIF1B,ABHD14A,CALM2,CDK5,PSMD1,RAD23B,PDS5B,MECR,AP2B1,NUP153,PLCL2,KCNAB2,CDC5L,SRP72,USO1,WDHD1,SLC25A5,ARF4,OGT,MPV17,COX5A,UQCRH,ATP6V0C,RTN3,ZMAT3,HSPH1,NDUFV2,COX5B,RECQL,POLR2K,GSPT2,CUTA,NDUFA4,CYCS,SLC35B1,SUPT7L,NDUFS4,MCTS1,CD59,ARPC5,ATIC,MSH2,CYC1,PPA1,TMED2,IFRD1,RB1CC1,PGS1,USP10,GORASP2,MRPL16,SRSF5,MATR3,PSMB3,RDH11,SEC31A,ETS2,RBMX,PPP3R1,MDH1,GPI,RNF14,MRPL3,ZNF207,NQO1,MAGED1,EIF3D,ACTR3,ANK3,NIT2,SNN,SDHA,APP,STAM,TERF2IP,MOAP1,APLP2,ZNF75D,ATP2A2,UTP18,RALB,MTMR4,ADCY9,NSFL1C,TTC3,NAA35,CCT2,HMGN4,EID1,DRAP1,RPL38,CRNKL1,NDUFA7,DNAJA1,TMEM147,H2AFV,FKBP3,KIF2A,PPP2CA,EIF3K,RAD51C,DDOST,HINT1,GOLGA8A,STAT1,WDR7,RNF38,TRIM32,PITRM1,LRP8,ADAM23,SLC25A12,LANCL1,RAB11A,REEP5,WRB,HMG20A,PIP5K1C,EBP,FBXO3,DNAJC8,NDUFA2,PTEN,NDUFB4,AHSA1,ARF5,LTN1,NDUFA3,UBE2M,MTX2,MOB4,PPP3CA,GUK1,GALC,TMEM126B,ILF3,LDHA,MRPS10,ECH1,FBXO21,PFDN4,PRDX3,CCDC6,TFDP1,OAZ2,LRPPRC,PPP1R11,ASNA1,DDX5,YWHAH,UBL3,DDX47,COPA,UQCR10,ENSA,MCCC1,CSNK2A1,BECN1,MAPK14,MRPL19,SSR1,PCNA,CDC42,TIMM23,GOT2,PHTF1,POP7,NFU1,EIF5,SRPK2,COPS8,DEAF1,RBX1,TLK1,PSMG1,PITPNB,RHEB,HSPB11,SH3GLB2,CAB39,KPNA2,MRPL13,NUDT11,RPS26,MYL12B,NUMB,UBE2D3,PPP1R2,PPP1R12A,LAMTOR3,KLC1,CHCHD2,RPL15,ASAH1,MEF2A,COX4I1,RAB6A,PPP3CB,XPO7,RGS2,SUB1,KIFAP3,ACAD8,CSNK1G3,NIPSNAP1,OXR1,ACSL3,RPL6,PSMA1,MAP4K3,EIF2AK1,ARPC1A,CAND1,GNAS,SDHB,UAP1,SYNCRIP,CDC27,COX7A2L,TBPL1,PITPNA,YWHAZ,TMEM14A,PTDSS1,GLT8D1,CHMP2A,NDUFA5,TOMM20,UGP2,MDH2,DYNLL1,SUMO2,PAIP1,IARS,CS,PDCD2,RPN2,BCAP29,PDIA6,HTRA2,PRPF19,POLR2G,PPT1,RAB7A,ATXN1,GLO1,NDUFB1,VDAC1,PDHX,GLOD4,PON2,HNRNPR,TIMM17A,MAPK1,AP2S1,SLC30A9,CDS2,CDC40,SMAP1,DCTN2,LETMD1,ARF1,AP3S1,DNAJB9,TFRC,MAN1A1,FGFR3,SLC1A4,H2AFY,PTGES3,ORC3,SLC35A1,RNF5,ADAM17,DCAF6,PSPC1,METTL5,ATP2C1,PRKAR1B,TUFM,RCOR1,ZFR,HLA-B,ATP6V1D,SEC23IP,ELMO1,COX8A,PGRMC1,ACAT1,SRSF3,PREPL,ATP6V1C1,IDH3B,PGAM1 |
| 5.569e-22 | -48.94 | RPA2 (replication protein A2) | protein interactions | 6118 | 449 | 155 | 17029 | 2761 |
RAB14,MAX,HNRNPAB,ADD1,COPA,THOC1,YTHDF3,CUL1,UBQLN2,RBM4,PABPC4,SF3B2,RAB8A,PCNA,RAB35,INTS1,AP2B1,KCNAB2,SEH1L,CDC5L,ERCC1,SNRNP200,SNRPB,HNRNPF,WDHD1,WDR82,SMC2,ESYT1,DIDO1,MCM2,RFC2,DHX15,PRIM1,GEMIN5,AHNAK,MAP4,U2SURP,ITGB1,ACTB,COPS6,ZNF598,SSRP1,PARP12,EWSR1,PPP1R12A,ZCCHC8,CHTF18,UBXN1,DHX9,RPL15,TOP2B,RAB6A,SMC3,EXOSC7,EIF2S2,MCM5,EFTUD2,XPA,CAPZA1,MSH2,GEMIN4,ATP6V0D1,PABPC1,TERF2,NTPCR,RB1CC1,PRRC2A,TEX10,RPL6,KRAS,MPG,EIF4G2,MATR3,XRCC5,EPRS,SYNCRIP,RBM25,TCOF1,RUVBL2,HNRNPDL,USP7,CHERP,RAB11B,SF3B1,CHD1L,TPX2,MYH9,ORC1,AP1B1,PRKACA,BCAP31,APP,RPAIN,HNRNPA2B1,STRBP,AKAP8,TARDBP,RBM15,RPRD1B,PRPF19,CDKN2AIP,RFC3,RAB7A,CUL3,DNAJC9,NFATC2,RAB1A,TRIM28,RPS9,SUPT16H,DDX17,PPP2CA,HNRNPR,RPLP1,FUS,TUBB,TMEM33,SCAMP3,TRIP12,EYA1,BLM,CSNK1A1,RMI1,TFRC,GOLM1,RFWD3,HUWE1,ARHGEF2,ANP32A,RPL19,TAGLN2,POLR1B,FBL,STAT3,HNRNPM,SMC4,SPTAN1,PRKDC,LDHA,TOP3A,ILF3,MEN1,SYMPK,SH3GLB1,PRDX1,ZFR,RPA1,MYO1F,DDX23,TPD52L2,BBX,PGRMC1,DDX5,RBPJ,DDB1 |
| 5.782e-22 | -48.90 | DUTERTRE_ESTRADIOL_RESPONSE_24HR_UP | MSigDB lists | DUTERTRE_ESTRADIOL_RESPONSE_24HR_UP | 309 | 115 | 17377 | 2626 |
POLA2,SKA3,FOXM1,SLC2A1,PTTG1,TPX2,SLC29A1,KIF2C,TCF19,STMN1,CD320,FANCI,KIFC1,PCNA,CCNA2,DUT,XRCC2,NUP107,RNASEH2A,SLC26A2,MYBL1,DNMT1,TACC3,PLK1,PPIF,RFC3,CELSR2,PBK,MKI67,RRM2,WDHD1,NFATC2,CDCA2,NUSAP1,CDC6,AURKB,BRCA1,SMC2,PKMYT1,ANLN,MCM2,SHCBP1,RFC2,ASF1B,RAD54B,CHAF1A,PRIM1,CDCA4,DSN1,RAD18,TONSL,RBL1,ZNF367,CEP55,H2AFX,DHTKD1,FKBP5,XRCC3,E2F2,CHPT1,POLQ,MCM10,CLSPN,CHTF18,CDT1,RRM1,KIF23,RACGAP1,HAUS4,BLM,NCAPG,RMI1,SPAG5,FBXO5,MAN1A1,EBP,TFAP4,DTL,SNRNP25,SUV39H2,CENPJ,MCM5,PRC1,TIMELESS,GTSE1,BCL2,KNTC1,CENPM,NUP85,IMPA2,GINS1,ABHD2,TK1,NASP,ASPM,MYBL2,CCDC34,KIF11,HAUS8,MASTL,ATAD2,POLE,BIRC5,CDCA5,TFDP1,CDCA7L,FAM83D,E2F1,SIAH2,WDR76,WDR62,CDK2,UBE2C,CCNB2,ESPL1 |
| 6.276e-22 | -48.82 | RCGCANGCGY_V$NRF1_Q6 | MSigDB lists | RCGCANGCGY_V$NRF1_Q6 | 838 | 232 | 17377 | 2626 |
CCDC93,POLA2,PDCD6IP,MAX,TMEM184B,NF1,ADAM10,PPP1R15B,UQCR10,ALKBH5,CNTROB,SND1,FKBP2,ABHD14A,GIT2,C14orf119,ZNF428,NAPG,PCNA,DPYSL2,RAB35,POP7,RAD23B,AP1M1,TECR,DNMT1,SENP1,MTPN,FTSJ3,ARID4A,SEH1L,CCAR1,ABCC5,MLST8,CDC5L,FYTTD1,TDP1,USO1,TMEM115,AATF,AKT2,HSDL1,WDHD1,TOPORS,DIDO1,CCNF,ICMT,CBFB,EIF3A,ARF4,ABHD5,IWS1,MKNK1,TBC1D17,BRD2,ATXN2L,SOCS4,ACTB,ARRB2,NUDT11,TSTD2,RTN3,DDX42,UBE2D3,EWSR1,PPP1R12A,PHF23,DHX9,LAMTOR3,TIA1,CTCF,PITHD1,PDXDC1,EIF2S2,MLX,INTS7,ARPC5,DAD1,KIFAP3,PCYT2,GEMIN4,CPSF4,ATP6V0D1,PABPC1,PHKG2,MORC3,PREB,EIF5A,C16orf72,NUDT4,DCAF8,SUGP2,RDH10,TYW1,FAM133B,BCLAF1,EIF2A,METTL22,KDM3A,MAP2K2,RXRB,MAGED2,GOLGA4,KPNA1,PALB2,ERGIC3,COX7A2L,VCPIP1,FAM122A,NUP62,SAMD8,SMPD4,WIPI2,SNRNP70,MZT2B,TMEM106C,BCCIP,NDUFA5,CHMP2A,CKLF,RWDD1,CHERP,MAGED1,WDTC1,PMS2,SDHA,TMEM161B,CD320,PAIP2,CSDE1,TMEM69,CCNA2,SHC1,KDM2A,UTP18,WDR44,PPME1,AKAP8,NUP107,EFCAB11,ABI1,NAA35,ZNF770,DVL2,PDCL3,CFL1,CSTF1,CPNE1,EID1,KAT7,GOPC,CIRBP,PCGF6,PRPF3,DNAJA1,CHMP2B,MBD3,TOLLIP,SERP1,TRIM28,CCDC127,SRSF1,PPP2CA,EIF3K,HINT1,VPS26B,TULP3,STK38,SAFB,AP1S1,REEP4,GEN1,PDCD2L,INTS2,CDS2,SCAMP3,ZFP91,MECP2,LETMD1,SMC6,CBLL1,SIKE1,ABHD14B,UBE4A,AKT1S1,IFT27,WRB,DNAJB9,FBXO5,GTF2F1,EBP,PTPN2,KIF5B,GART,SEC24C,FUT8,ANP32A,UPF2,OSTC,SGCB,UBE2M,SMC4,TXNL1,RHOA,KAT2A,PRKDC,PSPC1,MIER1,ATP2C1,ILF3,RFXANK,RABIF,RAB3IP,PCGF1,DDX39A,ARSK,NDRG3,SYMPK,POLR2A,SMAP2,FADD,RAB18,ATP6V1D,TTLL4,SNAP29,CAPN7,OAZ2,RGL1,PLOD3,USF2,THAP5,HIGD2A |
| 8.030e-22 | -48.57 | MODULE_83 | MSigDB lists | MODULE_83 | 302 | 113 | 17377 | 2626 |
CHMP2A,IER2,RPLP2,DYNLL1,EIF3D,FKBP2,CDIPT,OAT,STMN1,PCBP1,RBM4,BCAP31,RPL11,RPL23A,PSMD1,EIF4A3,TRA2B,STRAP,MTPN,PCBP2,MOSPD1,CDC37,RPL29,SEC61B,RPL35,POLR2G,CDC123,SNRPB,RPL38,PSMB7,DNAJA1,TMEM147,NDUFB1,VDAC1,EIF3G,SERP1,RPS9,RPSA,EIF3H,PLEKHF2,NSA2,RPL37,DAP3,HINT1,HNRNPR,RPS27A,PSMD8,PRDX5,RPLP1,RBMS1,UQCRH,KPNA2,BTF3,SNRPG,FAU,MYL12B,ATP6V0E1,PPIB,COX5B,NDUFV2,RPS15,RPS2,CDC40,PHB2,SRSF6,DAP,NACA,GADD45G,RPL15,RAB11A,NDUFS4,SUB1,EXOSC7,RPL17,DAD1,YBX1,RPL19,RBM3,MRPL21,PPA1,PABPC1,TMED2,EEF1D,ALDH9A1,LDHB,EIF5A,SRSF11,STAU1,RNASEH2C,TIMMDC1,RPS10,RPL6,LDHA,RPL8,PSMA1,RPS24,RPL27A,EIF4H,CCT8,PSMB3,PRDX1,ECH1,SDHB,GNAS,PFDN5,NAP1L1,KPNA4,RPL32,MAGT1,MDH1,ACADM,NDUFS5,HIGD2A |
| 8.392e-22 | -48.53 | CASORELLI_ACUTE_PROMYELOCYTIC_LEUKEMIA_DN | MSigDB lists | CASORELLI_ACUTE_PROMYELOCYTIC_LEUKEMIA_DN | 630 | 188 | 17377 | 2626 |
POLA2,HNRNPAB,ENSA,GLUD1,KIF2C,NANS,CCNB1,MAPK14,FANCI,EDC3,SSR1,KIFC1,RAD23B,SRI,AKR1B1,KIF22,TECR,TIMM50,SRPK2,CDC5L,PLK1,AATF,SNRPB,MRPL12,MKI67,HNRNPF,KIF15,RRM2,WDHD1,CDC6,AURKB,BRCA1,MCM2,LUC7L,ODC1,DHX15,GINS4,CHAF1A,OPTN,PAF1,STT3A,LUC7L3,PPM1G,BAZ1B,DHTKD1,KPNA2,PRPF4,ACTB,CHEK2,NUDT11,RTN3,PFKP,SSRP1,FUBP1,PPIB,CENPF,DHX9,RAPGEF6,SPAG5,LMNA,CD59,RNF121,SNRNP25,RPN1,EIF2S2,MCM5,ATIC,TIMELESS,YBX1,KIFAP3,PCYT2,CYC1,ATP6V0D1,PPA1,FAM171A1,LUC7L2,FDFT1,VOPP1,EIF5A,TRAFD1,AACS,NSDHL,ACSL3,PSMA1,CAPZA2,XRCC5,RDH11,EPRS,ETS2,ACLY,PRMT7,SNRNP70,CCNB2,TMEM14A,TMEM106C,EXOC3,FOXM1,IVNS1ABP,ACTR3,HNRNPUL2,TMEM97,ORC1,SDHA,BCAP31,HNRNPA2B1,CCNA2,DUS4L,TARDBP,CHTOP,PDIA6,CLN6,ILKAP,TMBIM1,DVL2,ENPP4,RFC3,MAPRE2,EID1,CDC123,CIRBP,HTATIP2,DNAJC9,NUSAP1,GLO1,NUP155,VDAC1,RAD54B,GLOD4,CHCHD3,CHMP4A,HSPA4,RBL1,TBL3,SAFB,CEP55,DNAJC17,COIL,TUBB,POLQ,CMAS,NADSYN1,FLOT1,PAWR,GGA2,NCAPG,FZD6,EBP,NDUFV1,DNAJC8,CTNNBL1,SEC24C,PRC1,GTSE1,FEM1B,NAP1L4,CENPM,TTLL12,HNRNPM,SLC25A1,SMC4,NUDC,LDHB,GINS1,PPAN,ELOVL5,TK1,NASP,CSRP1,ASPM,ABCF2,LDHA,ILF3,TUFM,MRPS10,RANGAP1,KIF11,PICALM,TSR2,RPA1,KEAP1,UPF1,BIRC5,HNRNPH3,ACAT1,SRSF3,IDH3B,YWHAH,ESPL1 |
| 9.436e-22 | -48.41 | GO_NUCLEAR_BODY | MSigDB lists | GO_NUCLEAR_BODY | 331 | 120 | 17377 | 2626 |
MBD1,USP7,SART1,ZNF496,MAX,SARNP,PNISR,THOC1,UBN1,CXXC1,SF3B1,SUMO2,RBM8A,ALKBH5,CCNL2,UBE2I,PRKACA,RBM4,RPAIN,PARK7,OIP5,MDM2,ZNF473,SP100,NEK6,EIF4A3,NSRP1,GLIS2,PIN1,SRSF4,TARDBP,FAM76B,CHTOP,RBM15,OGG1,CDK12,TIMM50,SRSF10,PRPF19,CDC5L,FYTTD1,SP3,TRIM8,NXT1,FAM118B,CRNKL1,RNPS1,DDX20,TOPORS,PRPF3,EAF2,GAR1,TOLLIP,LSG1,SRSF1,GEMIN5,EIF4ENIF1,CLK3,LUC7L3,HIPK2,NSMCE2,ARNTL,ATXN2L,PQBP1,PRPF4,CHEK2,COIL,CBX4,SMNDC1,GEMIN7,DDX42,NCOR2,SRSF6,CBLL1,SMC6,CDK13,THRAP3,BLM,CSNK1A1,METTL3,PRPF18,LMNA,RFWD3,RPA2,RB1,KLHL20,PTEN,PPP1R8,PPIG,EFTUD2,GEMIN6,CTR9,SS18L1,GEMIN4,FBL,MAML1,HNRNPM,LUC7L2,MORC3,YTHDC1,PSPC1,TOP3A,BCLAF1,SRSF5,PATL1,SF3A2,DAPK3,RPA1,RBM25,PML,PIAS2,DUSP11,SRSF3,SNRNP70,ZMIZ1,ZNF830,CDK2,HIPK3,CDKN2A,IFI16 |
| 9.517e-22 | -48.40 | KRIGE_RESPONSE_TO_TOSEDOSTAT_6HR_DN | MSigDB lists | KRIGE_RESPONSE_TO_TOSEDOSTAT_6HR_DN | 821 | 228 | 17377 | 2626 |
SRM,FGFR1OP,NOP2,MOGS,TMEM109,EBNA1BP2,SLC29A1,IKBIP,CUTC,EEF2K,PA2G4,NOL11,THADA,GOT2,TIMM23,THAP4,DPYSL2,ATG3,SIVA1,DNAAF2,TRMU,POP7,NOC2L,TAF5L,PRADC1,TRIM14,SEH1L,ELOF1,DEAF1,CCDC138,BAZ2A,AKT2,MRPL12,DCUN1D5,SOX4,LUC7L,GEMIN5,ALG3,BOLA3,TIMM13,RAD18,NIP7,TPP2,LUC7L3,WDR4,COX5A,STK11,RRS1,RPS26,HDAC2,FUBP1,HIVEP3,HSPH1,C9orf78,EWSR1,MUM1,SDC2,ASAH1,ZNRF3,PM20D2,DNAJB1,FAM136A,LYRM2,SRRT,FKBP1A,LYAR,CD59,SNRNP25,EXOSC7,C4orf3,SSBP3,BDH1,EI24,MDFIC,GEMIN4,ALDH18A1,MRPL21,LPCAT1,NAGPA,EIF5A,SRSF11,TIMM8B,DCAF8,RDH10,AMD1,ZNF574,MFNG,MRPL16,ADRB2,SEPT7,LY6E,VKORC1,MATR3,CYB5A,AKAP1,HSPBP1,GALNT2,RBM25,SYNCRIP,CCDC86,UAP1,DUSP3,PRPS2,PIAS2,SLC16A1,NUP62,TCOF1,NAA20,YY1,SNRNP70,CABLES1,ZBTB24,BCCIP,USP7,MMACHC,ANKRD27,CORO7,GNPNAT1,SLC2A1,UCK2,TMEM97,KLHL18,PRKACA,FARSA,ANKLE1,STRBP,CD3EAP,GRSF1,DUT,TNPO2,TARDBP,APOOL,TOP1MT,CLTB,GPD1L,ARL5A,GM2A,ACSL5,CLPTM1,TIMP2,FAM118B,HPDL,IDH3A,POLR2D,NLN,TMEM147,DNAJA1,VDAC1,ASB13,GAR1,DHX57,TMEM201,PEX5,DUS3L,TBL3,TIMM17A,GADD45B,NDUFA11,SCARB1,NCOA1,SPRYD4,BEND3,PDCD11,PPP2R2D,SLC25A39,COIL,CWC25,MIF,RRP15,PDAP1,B4GALT5,SRGN,MRI1,TCF3,MRPS26,SLC25A12,HMGN3,SDF2L1,GGA2,SPR,BZW2,HDDC2,TFRC,DNAJB9,PNO1,EBP,GOLM1,GART,AHSA1,FJX1,H2AFY,GEMIN6,COPS7B,DDX31,CENPM,POLR1B,LDLRAD3,TTLL12,GTF2H2,MSH6,SMC4,NUDC,PPAN,TELO2,NASP,DDX24,ABCF2,ILF3,LDHA,SCFD2,RANGAP1,LLPH,PRMT2,RPL27A,RHOT2,PRDX1,SLC19A1,INF2,TFDP1,LRPPRC,SLC25A19,IDH3B,NR2F2,CD81,GCSH,IFI16,GPATCH4,IPO4 |
| 9.815e-22 | -48.37 | primitive_neuroectodermal_tumour-medulloblastoma | COSMIC cancer mutations | primitive_neuroectodermal_tumour-medulloblastoma | 15815 | 2472 | 17385 | 2587 |
HECA,ZBTB10,ABCC10,HEXB,CCNL2,FBXO22,EEF2K,RAD23B,ATP13A3,DNM2,ZNRD1,FTSJ3,USP34,CCDC57,ERCC1,NRAS,EHMT1,KIF15,HNRNPF,WDHD1,MIER2,DIDO1,MCM2,RAB22A,SMAD2,MID1IP1,RPS27A,OGT,MPV17,COX5A,SMAD1,ZNF75A,ANXA11,SLC25A33,SEC61G,GGA1,MUM1,CCZ1,TRIO,CUTA,RAB23,KCTD17,HAUS4,EIF2AK4,APH1B,PARN,CDC73,MYL6B,ATG4A,TMEM179B,PDXP,SMC3,MVP,NUP85,NSUN4,PPA1,IFRD1,AGGF1,FOXK1,RBM42,GTPBP4,MAP7D1,MRPL16,ELK1,EIF4H,RDH11,MAGED2,KPNA1,ETS2,TYW5,WIPI2,RUFY3,PDLIM5,ACSF2,EXOC3,RHOG,STARD7,C5orf30,VTI1A,SLC35B2,INO80E,LCLAT1,RCOR3,CPNE3,KIAA1147,RBM23,ZNF420,AHCTF1,TBC1D22A,TBC1D14,GMEB1,NSFL1C,SEPT11,ZNF226,GPD1L,ZC3H3,ARL5A,PDCL3,SNX8,ERMP1,EID1,IDH3A,POLR2D,HTATIP2,MEF2D,TMEM147,GSTCD,TANC1,MAT2A,VPS26B,CORO1C,NSMCE2,CAMKMT,PPP5C,PITRM1,TUBB,COMMD10,ZNF445,SRSF6,HABP4,CCM2,FLOT1,BTN3A1,ATG2B,ABHD14B,PPP1R3B,GOLM1,ZBTB45,HUWE1,ZNF260,NAA50,ANXA5,LTN1,UBE3B,NAP1L4,ZNF710,ST8SIA2,MED22,SPTAN1,STAU1,TCTEX1D2,DDX24,TACC1,MRS2,LDHA,HEBP2,LLPH,RAB3IP,TTC33,PICALM,SH3BP5,SLC19A1,ACOX1,FAM3C,AEN,PARP10,YWHAH,THAP5,GPATCH4,FAM129A,TRIM11,YTHDC2,SNX15,RBM8A,ENSA,NENF,SND1,RUFY1,TRIM65,ZER1,PRNP,KRR1,RAB8A,NUP210,NT5DC1,NOC2L,EIF5,TACC3,VPS13B,PTPN18,MIOS,MBLAC2,SNRPB,CDC6,UTP3,PBRM1,USP21,TRAM2,FBXO28,BCL7C,ARRDC1,ADAM9,DVL1,NUMB,ZNF564,FUBP1,C1orf74,CTU2,PARP12,ZCCHC9,CENPF,LAMTOR3,CHCHD2,NCKAP1,LYRM2,RSAD1,TNS3,SUB1,RINL,SSBP3,MBD2,XPA,AHCY,RBM3,GLE1,MRPL48,LRSAM1,HDHD2,NTPCR,NSDHL,AMD1,CAMSAP1,ZNF761,METTL22,ICAM2,STYXL1,APPL1,BBS12,ANKRD46,RXRB,SDHB,PCM1,GALNT2,TMEM168,NLRC5,RUVBL2,BTBD10,MYO9A,CCNB2,USP7,GLT8D1,RPLP2,SUCLG1,ARID2,TMX4,SLC2A1,ATP6V1B2,PCBP1,LYN,BCAP31,VAV1,TMEM69,MRPL50,PSMA6,ZNF473,BRPF3,TARDBP,BCAP29,CTDSP2,PRPF19,PPIF,KDM3B,MND1,CLCN3,BIRC3,RAB7A,ANKRD33B,PPIE,CHMP2B,VDAC1,EIF3H,TMEM201,GLOD4,IDE,DHX16,UHRF2,CHMP4B,XRCC3,PARD3,BCL2L12,MCM10,C19orf53,KLHL21,PDAP1,CDCA8,TMX3,ARF1,SLC12A9,TUBGCP2,DNAJB9,HOMER1,POLR1B,RNF5,RBM15B,PPAN,RHOA,RPRD1A,BTAF1,TOP3A,ARHGEF12,PCGF1,DDX23,RAB18,CACNB1,PDCD6,ATP6V1D,L3MBTL3,FAM110A,NEIL3,CTBS,BBX,IMPDH1,TAF12,NR2F2,PGAM1,HIPK3,IFI16,TXN,H2AFZ,PNISR,TMEM203,PRKCSH,USP39,UBE2I,PARK7,SLC25A37,ASPHD2,ZNF428,RAB4A,TRA2B,SUCLG2,TAF5L,CISD2,SMARCE1,ZNF800,CDC5L,ZNF524,SGCE,OSBP2,NSUN2,USP22,CLNS1A,EIF3A,ZMYM3,DOT1L,IWS1,ANKRD10,WAS,KIF18B,TPP2,C1orf109,ZMAT3,B4GALT2,PRPF38B,RECQL,C9orf78,EWSR1,GADD45G,RRM1,ACAP1,B4GALT1,CYCS,FAM136A,SUPT7L,TMEM165,NPLOC4,CNOT3,WDR48,SPAG5,RTKN,CEP104,EXOSC7,KLHL5,LRRC8D,PPP4R1,MSH2,PIGG,FBXL7,MRPL40,TNRC18,SYTL3,FAM171A1,APOL1,EIF5A,GCC2,PRIM2,ELL2,RDH10,MFNG,RPS24,GORASP2,CAPZA2,ADRB2,CCT8,MTR,PHF6,PFDN5,SLCO4A1,TTC13,GOLGA2,RBMX,MED15,PIAS2,APPL2,SAMD8,NUDT3,CDKN2A,ZNF511,ATXN3,RAF1,KIAA0232,C2orf49,EPM2A,CD320,CCNA2,MTMR4,BRI3,TP53BP2,AQR,RBM12B,ILKAP,CDK12,SAP30,BRD4,DRAP1,NARF,LRRC8A,ELP4,ABHD11,PKMYT1,ASB13,SERP1,TRIM28,SUPT16H,EIF3K,CHMP4A,CBWD1,ATF6,XRCC4,PRPF4B,ADAM23,NDUFS1,DEPDC1,MECP2,SECISBP2,HMG20A,WWP2,JAKMIP1,SLC25A36,DNAJC8,AXIN2,CITED2,JMJD4,ANKRD37,KAT2A,TMEM126B,RABIF,ADSL,PACS1,BMS1,KCNQ1,ARSK,MACF1,KIF11,COMMD4,KLF6,SMAP2,FADD,SH3GLB1,MYO1F,CBX3,TMEM127,INF2,PPP1R11,DUSP11,DDX5,WDR62,TAF6,ESPL1,PURA,DDB1,DEF6,IPO4,FAM83G,UBL3,NAT9,PIGM,LYRM4,GPR132,UBE2Q1,PTP4A3,BRIX1,MRPL19,ZNF696,SF3B2,PCYOX1L,CDC42,SYNM,GOT2,JAZF1,HADHB,RPF2,SLC35C2,CNNM3,CARM1,SRPK2,WDR41,LARS,ZCCHC10,CCDC138,LRBA,SUMF2,KMT2C,PRPSAP1,ASF1B,RPL37,MAN2A2,EIF4ENIF1,NIP7,U2SURP,MIA2,ZNF268,VPS4A,ATP6V0E1,PPP1R2,PM20D2,XPNPEP3,RGS2,LYAR,FAM89B,POLR2I,TRAFD1,SUGP2,GBA,SYVN1,DAPK3,ARHGAP15,MASTL,UAP1,NFIL3,FN3KRP,YWHAZ,CTSA,TMEM14A,TOB1,TSEN15,ADNP2,TCF12,PRKAB1,MDH2,SMARCA4,RRN3,UBXN2A,IARS,CD3EAP,KIF14,EXOSC1,CS,CLTB,DNAL4,CSTF1,POU2AF1,UBQLN4,HPDL,PGGT1B,SELPLG,SMU1,ATXN1,GLO1,OGDH,BICD2,CADM1,EDEM2,HERPUD2,TOLLIP,FANCE,MBD3,PDHX,RPS9,ALKBH6,SURF4,DUS3L,ARNTL,ANP32E,FKBP5,TMEM101,CCDC125,ABCA1,PDCD2L,GCLM,RAE1,DCTN2,NUP54,CHIC2,PAWR,MXD4,DCUN1D4,PIP4K2A,XPR1,FERMT3,KIF5B,KLHL20,SEC24C,RRBP1,ARHGEF2,ANP32A,LDLRAD3,C12orf75,STAT3,MYO5A,NIPAL3,AMPD2,TXNL1,PHF20L1,DCAF6,FAM49B,TMEM39A,ATP2C1,RFFL,COG1,RCOR1,PRMT2,TFEB,LEMD2,UPF1,ELMO1,ZC3H7B,DTX4,ZMIZ1,TERF1,HRAS,CCDC93,FGFR1OP,TMED7,PIGQ,AGPAT1,CNTROB,PPP1R16B,MIS12,GSDMB,TTC9C,PDS5B,NUP153,SENP1,PGAP2,TMEM115,PLEKHM3,DCUN1D5,PLEKHF2,BRMS1,PWWP2B,TRIM47,WDR11,AXIN1,SMG9,TRIM52,LONP2,NDUFV2,PHF23,CERK,SLC4A2,EZH1,ITGB5,LMNA,FBRS,MCTS1,DDX56,EIF2S2,SLC38A5,FOXN2,CARS2,PRRC2A,C16orf72,RB1CC1,ZMYND11,PGS1,MYBL2,UHRF1BP1,SRSF5,MPG,MATR3,CYB5A,NCDN,POLR2J,SETD3,PTAR1,CNOT6,NDE1,EGLN1,ZNF207,ANKRD27,ABCA3,SARNP,IVNS1ABP,MON1B,RMI2,TMEM97,NIT2,NUF2,ZNF267,TCF19,TMEM161B,KTN1,APP,PRKD3,CLUAP1,ATP2A2,UTP18,DUT,ANAPC7,RNF19A,FAM76B,CLN6,TMEM9,GCC1,RNF169,ADCY7,ATP6V1G1,ENPP4,RNPS1,CDCA2,FKBP3,GPR137,DDX17,CHCHD3,PEX5,CDC16,HIPK2,MBOAT1,TICAM1,PDXK,ZBTB11,TMBIM4,GMCL1,UBE4A,IL21R,ETS1,WRB,ZNF92,PNO1,CAPN2,ADD3,SUV39H2,TTLL12,TPCN1,TMX1,LYPLA2,HNRNPM,LDHB,PPP3CA,NUDT8,POLK,JTB,EMP3,MTMR12,ZP3,PDE3B,KIF18A,CCDC6,WNT5B,MAPK6,C4orf46,LY75,SLC25A19,RGL1,PSAP,WDR76,IGBP1,FAF1,SNAPIN,COX15,AGRN,THOC1,GNPDA1,GPBP1L1,PPP1R15B,CSNK2A1,EBNA1BP2,GIT2,BIRC2,ATPAF1,DLG5,ABL2,XRCC2,ZFYVE27,MCMBP,PTPRK,CDC37,SP3,METTL1,EXOSC6,HARS,GMFB,ESYT1,ANLN,RAB5B,RHEB,DPYSL3,TBC1D17,TIMM13,CDCA4,TONSL,NRM,NAGLU,ACTB,ZNF45,TMUB1,CTCF,ASAH1,DOCK11,CRLF3,ASXL2,LRRC14,NUS1,SLC27A4,AFF1,MDFIC,MAML1,CYTH1,NQO2,UTP15,EIF2AK1,EIF4G2,ZDHHC3,MOSPD3,ITPRIPL1,CDC27,SNAP23,TBPL1,PRMT7,KCTD7,NDUFA5,CYLD,UGP2,DYNLL1,COPE,HCFC1R1,ZADH2,GGPS1,RPAIN,RAD23A,SEC11A,PDK2,ATP6V0B,STRBP,TNFAIP8,DUS4L,MRPL34,PDCD2,SAP30L,SLC39A9,CLPTM1,RPL29,RPL35,BTG2,DNAJC9,MTMR6,FRAT2,NFATC2,KDM1B,ARL5B,USP36,CCDC127,MRPL2,ATP1A1,CLK3,PSMD3,MAFK,CEP55,NDUFA11,DNAJC17,ZNF436,NCOA1,SLC25A39,ZC3HC1,ZNF146,ATXN7L2,CDC40,GOLIM4,SMAP1,RRP15,DAP,GNE,SMC6,ARFIP2,NKRF,CHAC2,BZW2,WRNIP1,SS18L1,CENPM,PTGES3,CAMK2G,MLEC,ZNF202,PPWD1,FAM50B,RHOT2,NEU1,TPD52L2,GOLGA7,TWSG1,GLG1,PGRMC1,FAM126A,SPCS3,RPS6KC1,UBE2C,PPCS,NDUFB6,TMEM41B,ZDHHC8,PLXNA1,CCNB1,SLC20A1,COMMD6,ABHD14A,POLR3K,C14orf119,ASAP2,SNUPN,CNPY4,TFG,PLCL2,SEH1L,ATG9A,PBK,MKI67,DDX20,AMDHD2,GALNT7,SLC17A5,CCNF,FOXRED1,RBM47,PTER,WDR4,DHTKD1,TRAF5,HDAC2,PWWP2A,HSPH1,LIME1,MAPRE1,CHTF18,ADO,KIF23,SLC35B1,NOTCH2,PMF1,JMY,FKBP1A,SLC31A1,SNX18,ATIC,ATP6V0A2,PIKFYVE,RNF135,LPCAT1,EEF1D,TMED2,PHF10,FTL,DDX28,ZNF84,SIGMAR1,PIP4K2C,RIT1,PLEC,KDM3A,SF3A2,FAS,EPRS,ZNF777,TMEM54,QARS,PPP3R1,TCOF1,NRBP1,CABLES1,DNMT3A,RWDD1,CKLF,TRIP10,SF3B1,CAST,SUZ12,RAC1,GPR89A,OLA1,GNB2,FLAD1,APLP2,KDM2A,TNPO2,CDKN1B,TALDO1,GPX4,ATP13A1,RFC3,MAPRE2,ERF,CUL3,SLBP,KIAA1586,H2AFV,POLG2,GAR1,PSMB9,DHX57,NSA2,HSPA4,MRPL55,JAK1,TBL3,SEL1L,H2AFX,KLHDC4,B4GALT3,PDCD11,ATMIN,POLQ,POU3F2,OTUD5,NCOR2,ANKRD13D,PKP4,SCAMP3,CDCA3,SLC25A12,BLM,TMCC3,GTF2F1,CRAT,AHSA1,PRC1,UPF2,COPS7B,SLC38A10,CNPY3,UBE2M,IFT46,TMEM160,TSHZ1,ZFP64,DENND4C,DENND1B,WDR18,RPL8,ILF3,LRRC1,RHOT1,TSR2,MARK2,ECH1,PRDX1,PLD3,NUCB1,FBXO21,GNA12,C1orf131,PRDX3,PFDN4,HNRNPH3,STX18,TFDP1,KHSRP,ASNA1,CPEB2,SSSCA1,BYSL,VPS29,S100PBP,MIB2,IER2,PTMS,NOP2,UBN1,NF1,DCAF15,FLYWCH2,ALKBH5,MOGS,TAF6L,MAPK14,BECN1,SNAPC4,RNF103,BCAT2,MBD4,C18orf32,METTL14,ZNHIT6,IMPAD1,RCSD1,PHTF1,SRI,KIF22,ZBTB22,NFU1,TRIM14,ELOF1,COPS8,FYTTD1,TRIM8,RRM2,SOX4,ABHD5,CXXC4,UBTF,PAF1,UEVLD,SPATA2,PQBP1,IARS2,ATXN2L,GALNT10,STARD3NL,RPS15,PIGN,AGTRAP,CIB1,XPO7,SRRT,ZNF449,CAPZA1,GLTP,BCL2,KIFAP3,N4BP2,HP1BP3,VOPP1,THNSL1,ISG15,CAND1,GNAS,TSC1,RBM25,CDCA5,ZFP90,NANP,RBBP4,ZBTB24,SMARCD1,MBD1,WASF2,MMACHC,TOMM20,IFI27L1,GNPNAT1,MPHOSPH8,HNRNPUL2,CHD1,MEAF6,C2orf68,CCDC50,AKAP8,PARL,RPN2,CHTOP,FAM3A,F2R,TMEM14C,SCYL3,ABI1,HTRA2,MOSPD1,RLIM,FAM172A,ZNF500,PSMB7,NLN,WIPF1,BUD13,NDUFB1,PEF1,EIF3G,BTBD1,TAB2,CHCHD1,TULP3,WDR59,CANT1,SCARB1,GAS2,USP11,SMURF1,PPP2R2D,TSPAN5,CDS2,MAGEH1,MRPL42,EYA1,CDK2AP2,MRPS26,LETMD1,KLF13,HDDC2,RGS1,MAN1A1,FBXO5,GART,PELO,TANK,BRD7,MRPL11,SAMD4B,ZDHHC18,GTF3C6,POLR3GL,WDR81,MEN1,ZNF407,MFN2,COX8A,ZRANB2,MBD6,SRSF3,ATP6V1C1,IDH3B,TATDN1,TSC2,LACTB2,CMTM6,RBM4,ZNF275,ANKRD39,RPL23A,CDKN2C,USF1,MECR,AP1M1,UPRT,CRY2,ECD,RNF26,TIPARP,LRRC59,ANKRD9,RHBDD2,MGAT5,BAK1,ZNF559,RHOBTB3,GABPA,WBP1,ARF4,GINS4,KRIT1,BOLA3,AHNAK,RAD18,PDRG1,RNASEL,CHPF2,PDCD4,SMNDC1,HIVEP3,KIAA0100,CLSPN,RHOC,DHX9,PDCD7,PSMD9,HAUS2,COPB2,TFAP4,CD59,RNFT1,RIMS3,MEGF8,EFTUD2,FBXO7,CPSF4,MRPL21,PHKG2,LUC7L2,SRSF11,EIF3L,MTA2,TYW1,USP10,ITM2A,SSR2,BCLAF1,MTX1,SFXN5,FNTA,PDLIM1,TXNDC16,ZNF830,TMEM159,MRPL3,ALS2,FAM72A,TRIM41,KARS,NQO1,POC1A,ANK3,PTTG1,TPX2,TBC1D13,DAZAP2,STMN1,GLRX3,REPS1,ABHD16A,FBXL6,SH3BP1,MTA1,UBA5,CLCN6,INTS12,C8orf59,RPRD1B,CGGBP1,CPNE1,SEC61B,POLR2L,FAM118B,GOPC,E2F3,CIRBP,RPL38,CRNKL1,PFKFB3,GORAB,RAB1A,GIGYF1,TMEM184C,PPP2CA,KIF2A,CCDC14,LSM6,RNF38,SNRPG,DMWD,USP13,MZT1,ZFP91,TRMT6,IP6K2,WDR5,SLC25A43,IFT27,PMVK,NEIL2,RRP36,SRXN1,RPA2,PSMD2,CLIC4,PDCD10,CBWD2,COQ4,ITGB8,ARF5,ARHGEF1,FBXL19,GTF2H2,TTPAL,UTP20,MAGT1,GPS2,DBI,SSNA1,MRFAP1L1,CD81,TMEM131,WDR13,FANCI,PAPOLA,CREM,TET3,FANCL,GLIS2,IL6ST,INTS1,POP7,SLC44A1,MTPN,ASB6,PLK1,RPP25,CELSR2,SEPT9,RBX1,APH1A,RAD51AP1,CKAP2L,PSMG1,UBE2V1,EAF2,IL12RB1,KRTCAP2,LUC7L,LSG1,NECAP2,C1orf122,ALG3,TRIM4,AGPAT2,CHD3,ZNF367,E2F4,PRPF4,KPNA2,BEND6,CLN3,DNAJC30,FAM208A,NGLY1,POT1,MYL12B,CCDC137,RMND5A,HJURP,PHB2,DNAJB2,FAM53C,NKD2,SDC2,KLC1,CDK13,ADCK5,COX4I1,DNAJB1,RAB6A,ARID1B,C1GALT1,MLX,UBE2Q2,CCP110,ZNF746,ARL6IP1,CTR9,NIPSNAP1,ABHD2,DCAF8,ACSL3,LDB1,MAP4K3,ARMC8,NMT2,IRF5,RPL36,HAUS8,MBIP,COX7A2L,ZDHHC7,SIL1,FAM122A,DTD1,UNC13C,BCCIP,SART1,TRAF7,NDUFAF2,TOR1AIP1,ZNF416,LAGE3,ZFYVE21,TM9SF3,RRAGC,ZNF121,NRF1,WDR44,PPME1,PIN1,EFCAB11,RPAP1,CABLES2,LMAN1,AHCYL1,TOP1MT,STRAP,SPSB3,ZNF583,SNX25,ARHGAP17,POLR2G,ZNF780B,PPT1,NUP155,DCLRE1C,MRPS14,RHBDF2,SUGP1,RBL1,FASTK,UBXN2B,STK38,AP1S1,SPRYD4,SLC22A23,H3F3A,CHID1,SMAD4,RAD51D,SLC30A9,CMAS,UNK,NADSYN1,HMGN3,NCAPG,SCYL2,FZD6,HERC3,GTPBP3,CTSS,ORC3,RNLS,YTHDC1,ACP2,HMGN5,CSRP1,METTL5,ABCF2,TUFM,RANGAP1,PNPLA8,HAGH,API5,ZFR,SEC23IP,E2F1,TMEM219,USP20,RBPJ,PDCD6IP,MAX,LUZP1,GXYLT1,ADAM10,CXXC1,TSC22D3,AP3M2,CUL1,GYG1,NANS,MYEF2,ANKRD26,NOL11,FIZ1,ZNF200,MARCH2,SLC26A2,SRP72,KLF10,LACTB,RFC2,CBFB,RAB2B,MAP3K4,HHEX,LUC7L3,RPS14,MAP4,MRPL27,BTF3,PTPDC1,NMD3,CCDC59,PTOV1,COX5B,DNAJC5,SCOC,DHPS,POLR2K,ANKH,C16orf87,PRKAA1,VAV2,GSPT2,TATDN3,DLGAP4,PXMP2,PRPF39,PSEN1,ZNF79,PDXDC1,VPS25,NDUFS7,YY1AP1,C12orf10,FAM192A,RPN1,LHX8,ARPC5,ZNRF2,TPST1,DAPK1,PIK3IP1,CYC1,SOCS5,FDFT1,PIGT,EMB,WDR1,ZNF574,C1orf35,EXOSC9,ARID1A,PTTG1IP,C9orf40,FXR1,GOSR1,TWISTNB,AKAP1,XRCC5,HMGN2,PI4K2A,CAT,DERL1,HSPBP1,MTHFD2,ARAP1,USP32,FAM83D,CABIN1,SMPD4,GPI,CYTIP,TP53RK,REPS2,RAB11B,UROD,SLC39A13,POMP,BCL2L1,NUDT19,DECR1,RALB,SIAH1,LPIN2,ADCY9,MRPS27,SOCS6,TTC3,RNASEH2A,CFL1,ANKLE2,CDC123,VDAC2,EDF1,EML4,ERC1,AMZ2,ANKZF1,ZNF282,DSN1,DDOST,HINT1,DGCR8,SAFB,HAGHL,LMBR1,RWDD4,FTSJ1,NCLN,BEND3,EYA2,DYNC1LI2,SLC41A1,B4GALT5,MANBA,TKT,FAM76A,CBLL1,ARGLU1,LANCL1,POFUT1,FAM8A1,HEATR5B,HLA-A,EBP,RFWD3,NDUFA2,FUT8,BTF3L4,PTPN11,MRPL54,FEM1B,RPL19,CNN2,NDUFA3,MTX2,MSH6,PDLIM2,LONRF3,RFXANK,FBXO9,GUF1,RPL32,ZHX1,NDUFS5,WDR91,GPR89B,HIGD2A,ZBED3,RORB,POLA2,ZNF76,COPA,UQCR10,HMGXB3,PHRF1,ABCB10,COMMD5,MAP1LC3B,DST,SIVA1,RAB35,GPATCH1,DRAM2,DEAF1,SNRNP200,NCK1,LAP3,VHL,SREK1,ARHGDIB,PITPNB,HSPB11,BRWD1,PPM1G,SH3GLB2,CRCP,BAZ1B,CAB39,ACBD4,STK11,CLU,CHEK2,ZSWIM3,TSTD2,CHPT1,MRPL13,DCAF5,CAPN1,UBE2D3,NSMCE4A,PPP1R12A,ZCCHC8,GORASP1,NACA,UBXN1,PCSK7,RPL15,THRAP3,TTF1,QSOX2,PRPF18,NUP205,CHKA,DTL,MED10,ZRANB1,MCPH1,SLC12A2,ATP6V0D1,CSNK1G3,CREG1,NUDT4,RPL6,VKORC1,SLTM,EVC2,KLHL15,SIAH2,SLC16A1,EHD4,SNRNP70,C11orf1,APOL2,N4BP2L2,SNX27,CHMP2A,CORO7,FEZ2,UCK2,PMS2,UCK1,CLCC1,EXT2,MXD1,USP5,HNRNPA2B1,SAP130,NVL,PPP6C,CYB5R1,ZNF770,EBAG9,RNF25,PCGF6,METTL2A,FAM72B,PON2,HNRNPR,HPS5,STAT6,MAPK1,BRD9,TMEM33,NAT14,DNAJC2,TRIP12,SHPRH,SCYL1,VPS45,MYO9B,GFM2,SPPL2A,FASTKD3,FGFR3,MZT2A,PPIG,ZDHHC13,TMEM99,H2AFY,ATG13,NDUFS8,ERI3,FBL,FRMD8,SLC35A1,MICAL3,TGFB1,B3GALT6,ELOVL5,HEMK1,TIMMDC1,HELB,PSPC1,MIER1,SCFD2,NDRG3,CDK11A,MTMR3,MEGF9,ACAT1,CENPT,PLOD3,RAB3IL1,ZSWIM6,RAB14,ADD1,MRPS15,KDM4A,XIAP,DHX8,GLUD1,ANKRD23,PABPC4,CALM2,CDK5,PSMD1,NEK6,NSRP1,RABGAP1L,SRSF4,FNIP2,KCNAB2,PCBP2,PLK3,ZNF672,MRPL43,HSDL1,TOPORS,MCL1,SMC2,PPFIA3,ICMT,SLC50A1,STOML2,LIMK1,ZNF689,PRDX5,ATE1,MLYCD,ATP6V0C,ST3GAL2,FBXL3,TFDP2,E2F2,PFKP,AAAS,DDX42,SSRP1,MRPL9,MRPS2,STRN4,TOP2B,ZNRF3,TMED3,DDRGK1,RAVER2,GNS,INTS7,INPP5A,MCM5,PHF14,ZNF326,UBE2QL1,NAGPA,TIMM8B,ETV3,TSPAN31,DHX29,TEX10,MAN1B1,RPS10,CBFA2T2,ABCF1,RHOB,LRRC14B,DTWD1,PTPRF,SCARB2,OSBPL11,CCDC86,DUSP3,SLAIN1,MDH1,HEXA,RNF139,SNX14,ZNF296,TRERF1,UBR2,CHD1L,ACTR3,WDTC1,MYH9,CREBL2,NIPA2,PRKACA,SAFB2,ANKIB1,STAM,ARL6IP6,RAB21,SP100,ZKSCAN1,DDA1,NUP107,ANKRD13C,MAVS,CEP63,TMEM136,RBM15,ATF2,DCTN1,SHOC2,PSRC1,MAP4K4,WBP2,ATP6V0A1,NUSAP1,DNAJA1,NDUFA7,TAZ,TAF2,SEC61A1,WDR7,RPLP1,CBLN2,RBMS1,FUS,GEN1,LRP8,COIL,LRCH1,GALK1,ZNF786,RPS2,SESTD1,TRAK1,JMJD6,SIKE1,AKT1S1,KRI1,FBXO3,ERH,GATC,PPP1R8,PRDM4,GTSE1,GEMIN6,DCP1A,SGCB,S100A6,IMPA2,NUDC,PDPK1,TK1,GUK1,TNFAIP3,GALC,ZNF512,KIAA0930,MRPS10,DDX39A,RPA1,ZNF862,ZNF180,KEAP1,POLE,TATDN2,PITX1,CAPN7,LRPPRC,PML,HMGB2,USF2,ANAPC4,SRM,DDX47,MCCC1,CDC42SE2,S1PR2,CDIPT,SEC16A,KCMF1,SSR1,LIN9,PCNA,ZNF639,TRMU,PIK3R2,ETV6,PPCDC,TXLNA,FAM86C1,MYBL1,MRPL32,CCAR1,ABCC5,PBXIP1,TLK1,MRPL12,EZR,LNX2,LRP5,BRCA1,PRKRA,STX16,EPB41,OPTN,SEPT1,SOCS4,QRSL1,PIEZO1,GLCCI1,NUDT11,GEMIN7,LZTR1,RACGAP1,PPP3CB,B4GALT4,RLF,RAPGEF6,SNRNP25,RB1,VASP,MED8,VMP1,PPIL2,MEA1,TIMELESS,AHDC1,ALDH18A1,TMEM8A,ABCC1,PREB,TRAPPC9,AACS,MEMO1,KRAS,RTF1,UBE4B,NFATC2IP,LY6E,ARPC1A,ZNF174,PSMC4,GOLGA4,SYNCRIP,PALB2,PRPS2,NIPA1,TIGD2,RNF114,FOXM1,MRPL39,XAB2,DUSP22,COMMD8,RPL11,CSDE1,MDM2,CORO1A,METTL9,MINPP1,POC5,DVL2,GM2A,PSMA8,COQ10B,CPOX,TIGD5,SLC26A6,CYP20A1,PRPF3,TXNL4A,RPSA,SRSF1,DNAJC10,SCAP,ZNF700,PLEKHG4B,TIMM17A,FAU,LTA4H,AP2S1,USP53,CTDP1,MIF4GD,CDT1,ARID5A,SUMF1,GGA2,AP3S1,CSNK1A1,RMI1,TFRC,PTPN2,IRF4,STARD9,GSTK1,NDUFV1,SLC1A4,CWC27,SLC35B4,DDX31,ABCD1,RPAP3,CNTN5,SNX2,ZMYM5,CCDC34,CHCHD6,BSDC1,KPNA4,CDKN2AIPNL,FBXO41,BIRC5,TFE3,SNAP29,CDCA7L,PKD2,ACADM,CHMP7,SAT2,GCSH,ZNF496,TMEM109,TAP1,NHLRC3,IKBIP,EIF1B,ELMOD2,KIFC1,DBNDD1,CYB5RL,PARPBP,RNASEK,CDC25B,PRADC1,DNMT1,NOL12,USO1,AKT2,NOL8,GNG7,AURKB,MCFD2,SLC25A5,ZFAND5,MAK16,STT3A,TMED10,PSMD8,EIF2D,ITGB1,PTPN7,UQCRH,RRS1,ARRB2,RTN3,ZNF598,SVIP,DDX58,WSB2,PPIB,MUT,GMFG,HLA-E,NDUFA4,MAN2B1,METTL3,CFLAR,NDUFS4,RNF121,MEX3C,KLF16,HDAC7,DAD1,BDH1,PCYT2,GNAI2,ANKHD1,TERF2,MORC3,KCTD20,SEPT8,DCTD,TOMM40,PATL1,ADSS,SERTAD2,SERF2,ZFP92,NSF,DCK,ERGIC3,ACLY,LPCAT4,VCPIP1,YY1,PPP6R2,PPP6R3,MAP3K5,RNF14,CDK2,ZC3HAV1,SYS1,ZBTB37,URB2,EIF3D,MAGED1,KLHL18,ADPGK,SLC25A44,AP1B1,SDHA,PHC2,CRKL,TERF2IP,MOAP1,CYHR1,ZNF75D,SHC1,UCHL5,NAA35,TMBIM1,CCT2,CDKN2AIP,MKLN1,LYRM1,GALK2,CDC23,SHCBP1,AP4E1,PRDM11,VEZF1,PPP2R5A,ACYP1,STAT1,PPA2,TRIM32,RHEBL1,C1orf112,TCF3,MRI1,BRAP,AGPAT3,MYNN,SDF2L1,SPR,RAB11A,REEP5,FOXO3,MAD2L2,CCDC28A,PIP5K1C,RBM17,MAT2B,PTEN,CENPJ,TAGLN2,CREB1,PACS2,NCOA2,SMC4,RNASEH2C,NEK7,NET1,PARP4,TBRG4,ANAPC2,RPL27A,YIF1A,SGSH,HGS,TTLL4,SLC38A7,MFAP1,CCDC69,BRWD3,ESYT2,SKA3,NPHP4,UBE2E2,HNRNPAB,PLXNC1,ST13,TMEM184B,DNAJC24,ZNF107,KIF2C,SLC29A1,AGFG1,SIRT2,FKBP2,USP48,SNRPD3,UBQLN2,CUTC,EDC3,UBLCP1,ZNF804A,RAP1A,THADA,EIF4A3,AP3S2,ATG3,DPYSL2,PPP1R12C,AKR1B1,NDUFB9,JOSD1,RP2,TTC4,TECR,ARID4A,FGFR1OP2,TIMM50,TDP1,DPM1,FOPNL,SLC16A7,WDR82,SLC25A22,STK17B,DHX15,CHAF1A,GEMIN5,COPS6,SASS6,RPS26,PSMC1,SLC12A7,TBC1D12,TM9SF4,ZNF768,UFC1,MED13L,TIA1,MEF2A,EPHX2,PITHD1,RHBDD1,NFATC3,BANF1,ZNF335,BUD31,YBX1,KNTC1,ACAD8,UBE3C,ZNF189,ALDH9A1,KDELR1,TSTA3,CIC,PSMA1,SEPT7,NAP1L1,EXOC4,KIAA1328,PITPNA,NAA20,PTDSS1,MZT2B,PDSS2,C7orf26,TMEM106C,IMMT,ASH1L,CHERP,WDYHV1,PLAGL2,CHKB,IRF3,TWF2,ANKRD28,FARSA,SAR1A,SCAMP4,APOOL,PDIA6,ACSL5,TOR1AIP2,AZI2,GFER,RAD54B,TMEM41A,DAP3,ZNF317,GADD45B,AKNA,REEP4,CBX4,MIF,KIF3B,GOLPH3L,SH2D3A,CASP6,TOR3A,SRGN,DBF4,MFSD10,SAC3D1,CTNNBL1,YIF1B,CLDND1,TTC17,SLC25A1,GINS1,CSNK1G2,TELO2,ADAM17,HMGN1,NASP,ASPM,PPP1R21,PRKAR1B,SYMPK,TARS,SNRPA,MAPK3,HSPA1B,HLA-B,ATAD2,PLAA,ZNF330,OSBPL8,KBTBD7,PREPL |
| 1.370e-21 | -48.04 | FBXO6 (F-box protein 6) | protein interactions | 26270 | 619 | 194 | 17029 | 2761 |
COPA,ADAM10,HEXB,CUL1,PLXNA1,IKBIP,OAT,SSR1,PCYOX1L,SF3B2,PCNA,NUP210,EIF4A3,TIMM23,HADHB,DNM2,FBXW2,RPF2,TTC4,CNNM3,PCBP2,TIMM50,CDC37,PLK1,COPS8,SNRNP200,DPM1,RBX1,HNRNPF,EZR,SLC25A22,SMC2,SLC25A5,DHX15,ARF4,EIF3A,CLNS1A,STOML2,GEMIN5,MAN2A2,STT3A,TMED10,NRM,NAGLU,ITGB1,CLU,VPS4A,COPS6,NGLY1,CHPF2,PSMC1,PFKP,PPIB,HSPH1,DHX9,RRM1,ASAH1,MAN2B1,COPG2,NUP205,NDUFS7,COPB2,LMNA,GNS,RPN1,SMC3,MCM5,MEGF8,CAPZA1,CTPS1,YBX1,AHCY,CYC1,PPA1,PABPC1,NUP85,EEF1D,FDFT1,CREG1,ERLIN1,ERO1A,RPS10,RPL6,GBA,PSMA1,PKM,CCT8,EPRS,SYNCRIP,TTC13,RBMX,SIL1,YWHAZ,CTSA,RUVBL2,ATP5F1A,RBBP4,HEXA,HNRNPDL,RHOG,KARS,IMMT,RPLP2,IVNS1ABP,SF3B1,UCK2,SMARCA4,PCBP1,SDHA,ANKRD28,HNRNPA2B1,SEC11A,FARSA,IARS,PPP6C,TARDBP,RPN2,MINPP1,PDIA6,STRAP,CCT2,RFC3,PPT1,VDAC2,TOR1AIP2,NUP155,DNAJA1,TRIM28,RPS9,TMEM201,MAT2A,SRSF1,DDX17,PON2,ATP1A1,DDOST,HNRNPR,PSMD3,STK38,SEL1L,ATF6,NCLN,SCARB1,B4GALT3,TUBB,GALK1,CMAS,NDUFS1,SCAMP3,MANBA,TKT,SLC25A12,SDF2L1,ARF1,ATP5F1B,SCYL2,POFUT1,TFRC,GART,HUWE1,AHSA1,ARHGEF2,COPS7B,TTC17,HNRNPM,SLC25A1,SMC4,TGFB1,ADAM17,ACP2,PRKDC,ABCF2,LDHA,RPL8,ILF3,TUFM,DDX39A,RHOT2,KIF11,NEU1,HSPA1B,RPA1,PLD3,SGSH,MAGT1,LTBP4,RPL32,LRPPRC,ACAT1,DDX5,SPCS3,PSAP,PLOD3,TMEM131 |
| 1.458e-21 | -47.98 | MORF_ACP1 | MSigDB lists | MORF_ACP1 | 207 | 88 | 17377 | 2626 |
RAB14,SART1,TOMM20,RPLP2,EIF3D,SUMO2,COPE,STARD7,UBE2I,GNB2,PARK7,RAD23A,CALM2,RAB8A,DUT,CS,TRA2B,TARDBP,TCEA1,PDIA6,STRAP,PCBP2,SRP72,CCT2,SNRNP200,BAZ2A,TLK1,PPIE,PSMB7,RNPS1,VDAC2,NDUFA7,USP22,H2AFV,EIF3G,TRIM28,DHX15,RHEB,EIF3H,NSA2,EIF3K,BRD2,HINT1,DDOST,HNRNPR,RPS27A,SAFB,UQCRH,BTF3,MAPRE1,MRPL9,PHB2,NACA,XPO7,NDUFS4,ERH,DNAJC8,NDUFV1,PPIG,ANP32A,H2AFY,YBX1,PTGES3,NAP1L4,HNRNPM,HMGN1,RHOA,WDR1,ILF3,TUFM,JTB,PSMA1,EIF4H,DDX39A,EIF4G2,SF3A2,CBX3,XRCC5,GNAS,NAP1L1,HGS,CSK,TATDN2,LRPPRC,YWHAZ,SRSF3,SNRNP70,TERF1 |
| 1.465e-21 | -47.97 | HALLMARK_E2F_TARGETS | MSigDB lists | HALLMARK_E2F_TARGETS | 196 | 85 | 17377 | 2626 |
POLA2,H2AFZ,PTTG1,PMS2,KIF2C,STMN1,TCF19,CDKN2C,PA2G4,PCNA,DUT,POP7,NUP107,PDS5B,CDKN1B,TRA2B,KIF22,NUP153,CDC25B,RNASEH2A,DNMT1,TACC3,PLK1,RFC3,RAD51AP1,SNRPB,MKI67,RRM2,SLBP,AURKB,BRCA1,MCM2,RFC2,GINS4,ASF1B,SRSF1,RAD51C,KIF18B,LUC7L3,H2AFX,KPNA2,ANP32E,CHEK2,TUBB,SSRP1,DEPDC1,CDCA8,CDCA3,CTCF,SMC6,RACGAP1,TFRC,SPAG5,NUP205,LYAR,RPA2,SMC3,CCP110,MCM5,PPP1R8,MSH2,TIMELESS,CENPM,SMC4,GINS1,TK1,NASP,PRIM2,PRKDC,MYBL2,ILF3,TBRG4,DDX39A,RPA1,NAP1L1,MTHFD2,ATAD2,SYNCRIP,POLE,BIRC5,DCK,HMGB2,CCNB2,ESPL1,CDKN2A |
| 1.520e-21 | -47.94 | MORF_G22P1 | MSigDB lists | MORF_G22P1 | 164 | 76 | 17377 | 2626 |
ZNF207,KARS,TOMM20,H2AFZ,DYNLL1,EIF3D,SUMO2,STARD7,AP1B1,UBE2I,PARK7,RAD23A,PCNA,TRA2B,TARDBP,PDIA6,STRAP,CDC37,CCT2,SNRNP200,EID1,CDC123,SNRPB,PSMB7,RNPS1,VDAC2,USP22,H2AFV,TXNL4A,EIF3G,TRIM28,DHX15,EIF3H,CLNS1A,NSA2,EIF3K,HSPB11,PSMD8,PPM1G,UQCRH,BTF3,FAU,COX5B,NDUFV2,PHB2,NACA,DHX9,COX4I1,MYL6B,NDUFS4,ERH,NDUFV1,YBX1,FBL,HNRNPM,HMGN1,POLR2I,WDR1,TUFM,JTB,COMMD4,EIF4H,EIF4G2,SNRPA,PSMB3,CBX3,XRCC5,SDHB,NAP1L1,RBMX,ACLY,IMPDH1,MDH1,SRSF3,NDUFS5,IDH3B |
| 1.653e-21 | -47.85 | nuclear speck | cellular component | GO:0016607 | 381 | 130 | 18223 | 2701 |
PNISR,THOC1,KMT2E,CXXC1,RBM8A,ALKBH5,CCNL2,PPP1R16B,MAPK14,RUFY1,RBM4,SF3B2,MBD4,NEK6,NSRP1,EIF4A3,GLIS2,SRSF4,KIF22,CRY2,TAF5L,CARMIL1,OGG1,TIMM50,SRSF10,CDC5L,FYTTD1,BAZ2A,SREK1,TOPORS,USP22,EAF2,DHX15,EIF4ENIF1,BRD2,LIMK1,LUC7L3,PQBP1,ATXN2L,PRPF4,SMNDC1,DDX42,PRKAA1,CDK13,THRAP3,METTL3,LMNA,PRPF18,TMEM179B,EFTUD2,CTR9,MAML1,LUC7L2,HP1BP3,SRSF11,AGGF1,BCLAF1,SRSF5,PATL1,SF3A2,RBM25,PIAS2,ZNF830,SNRNP70,TCF12,MBD1,SART1,SARNP,SF3B1,RAF1,RMI2,POMP,DAZAP2,PCBP1,PRKACA,SAP130,OIP5,PIN1,TARDBP,TAP2,FAM76B,CHTOP,RBM15,CDK12,RNF169,PRPF19,NXT1,PPIE,RNPS1,POLR2D,CRNKL1,SMU1,ATP6V0A1,PRPF3,ERBIN,NDUFB1,USP36,DDX17,SRSF1,AFDN,CLK3,H2AFX,CBX4,PRPF4B,CWC25,TRIP12,SRSF6,HABP4,TCF3,TKT,CBLL1,SMC6,CSNK1A1,PPP1R8,PPIG,GTF2H2,SMC4,YTHDC1,PSPC1,DENND1B,API5,DDX39A,HSPA1B,TATDN2,DUSP11,ACADM,SRSF3,ZMIZ1,IFI16,S100PBP |
| 1.773e-21 | -47.78 | macromolecule modification | biological process | GO:0043412 | 3348 | 691 | 17256 | 2622 |
FGFR1OP,KDM4A,MAP3K7CL,PIGQ,XIAP,TGOLN2,FBXO22,EEF2K,CDK5,PSMD1,NEK6,RAD23B,CRY2,NUP153,FNIP2,RNF26,TIPARP,ANKRD9,MGAT5,SENP1,FTSJ3,USP34,PLK3,PGAP2,TMEM115,NRAS,EHMT1,MIER2,TOPORS,DCUN1D5,ICMT,ARF4,BRMS1,SMAD2,RAD18,RPS27A,LIMK1,AXIN1,OGT,ATE1,VIPAS39,ST3GAL2,RNASEL,KLHL42,FBXL3,SMAD1,AAAS,ZNF720,CLSPN,TRIO,TOP2B,EZH1,EIF2AK4,ZNRF3,PSMD9,PARN,CDC73,ATG4A,DDRGK1,PDXP,RNFT1,FBXO7,NUP85,PHKG2,NSUN4,UBE2QL1,NAGPA,FOXK1,MAPKAPK3,MTA2,ERO1A,MAN1B1,ARMT1,USP10,MPG,PTPRF,FNTA,DUSP3,CSK,SETD3,TEX30,TYW5,PTAR1,WIPI2,CFAP20,SGF29,RNF139,NUP58,EGLN1,TRIM41,KARS,UBR2,WDTC1,RXYLT1,INO80E,PRKACA,STAM,CPNE3,ANKIB1,KTN1,APP,PRKD3,FBXL6,MTA1,DDA1,UBA5,NUP107,ANAPC7,RNF19A,MAVS,ATF2,RPRD1B,RNF169,ULK3,KAT7,MAP4K4,RAB1A,FKBP3,PPP2CA,PEX5,CDC16,NSMCE2,HIPK2,CAMKMT,RNF38,DMWD,PPP5C,USP13,RPS2,ZFP91,TRMT6,CCM2,TRAK1,JMJD6,UBE4A,WDR5,NEIL2,PPP1R3B,GOLM1,FBXO3,PSMD2,SUV39H2,HUWE1,PRDM4,NAA50,LTN1,KANSL2,UBE3B,TTLL12,ST8SIA2,FBXL19,GTF2H2,LYPLA2,SPTAN1,PDPK1,PPP3CA,TNFAIP3,USP42,ZNF862,KEAP1,MAGT1,GPS2,DBI,MAPK6,LRPPRC,PML,PARP10,WDR45B,ANAPC4,TRIM11,PPP1R15B,CSNK2A1,BIRC2,ZER1,FANCL,TET3,ABL2,RAB8A,PCNA,NUP210,TRMU,ASB6,RYBP,PTPRK,CDC37,PLK1,SP3,METTL1,PTPN18,EXOSC6,RBX1,BAZ2A,SNRPB,TLK1,GMFB,UBE2V1,BRCA1,KRTCAP2,PRKRA,USP21,TRIM4,ALG3,CHD3,SOCS4,ARRDC1,ACTB,OSGEPL1,NGLY1,NAA60,SEPHS2,RMND5A,CTU2,LAMTOR3,SDC2,ADCK5,CDK13,RAB6A,PPP3CB,B4GALT4,RLF,ASXL2,C1GALT1,NUS1,UBE2Q2,MED8,CCP110,MBD2,CMTR2,PPIL2,CTR9,MDFIC,MAML1,LRSAM1,DCAF8,LDB1,KRAS,EIF2AK1,MAP4K3,RTF1,UBE4B,NFATC2IP,LY6E,METTL22,STYXL1,ZDHHC3,NMT2,PSMC4,MBIP,GALNT2,CDC27,ZDHHC7,PRMT7,RUVBL2,RNF114,USP7,KCTD7,CYLD,TRAF7,SUMO2,LYN,DUSP22,RAD23A,PDK2,PSMA6,MDM2,BRPF3,KMT5C,DUS4L,ABRAXAS2,PIN1,PPME1,MINPP1,LMAN1,SAP30L,CTDSP2,SPSB3,PRPF19,KDM3B,PPIF,BIRC3,PPT1,PSMA8,BTG2,PPIE,MTMR6,NUP155,KDM1B,USP36,CLK3,FASTK,PSMD3,STK38,UHRF2,NCOA1,USP53,SMAD4,ZC3HC1,CTDP1,KLHL21,TMX3,CDCA8,SUMF1,CDK11B,CSNK1A1,SCYL2,PTPN2,HERC3,GTPBP3,IRF4,CWC27,CAMK2G,RNF5,CNTN5,RPRD1A,RHOA,PRKDC,RANGAP1,PPWD1,PCGF1,FBXO41,NEK1,GOLGA7,BIRC5,USP20,TAF12,RPS6KC1,UBE2C,HIPK3,GCSH,NUP188,GXYLT1,PRKCSH,ADAM10,ZDHHC8,CXXC1,USP39,CUL1,NHLRC3,CCNB1,UBE2I,PARK7,ASPHD2,FBXW2,TAF5L,MARCH2,CDC25B,MAST2,DNMT1,SEH1L,AKT2,PBK,NSUN2,GALNT7,AURKB,USP22,CCNF,MCFD2,CBFB,DOT1L,MAP3K4,MKNK1,RBM47,STT3A,PSMD8,TPP2,WDR4,PTPN7,PTPDC1,ARRB2,ZNF598,HDAC2,B4GALT2,DDX58,WSB2,PPIB,GMFG,DHPS,PRKAA1,B4GALT1,CYCS,MAN2B1,SUPT7L,PSEN1,TMEM165,METTL3,WDR48,FKBP1A,RNF121,RPN1,KLHL5,ZNRF2,HDAC7,DAD1,PPP4R1,PIGG,DAPK1,TPST1,FBXL7,RNF135,MRM3,APOL1,MORC3,SOCS5,EIF5A,PIGT,COQ8A,MFNG,ADRB2,KDM3A,MAP2K2,PSMB3,DERL1,GOLGA2,EPOP,CSNK1G1,PPP3R1,USP32,PIAS2,DCAF11,VCPIP1,YY1,MAP3K5,RNF14,CDK2,NRBP1,ZC3HAV1,NDC1,TP53RK,DNMT3A,ATXN3,RAB11B,RPS6KA1,RAF1,SUZ12,RAC1,KLHL18,CRKL,APLP2,CCNA2,SHC1,KDM2A,SIAH1,MTMR4,UCHL5,SOCS6,TTC3,NAA35,ILKAP,CDK12,CFL1,MRM2,SAP30,TAOK1,CUL3,ELP4,KIAA1586,PKMYT1,ASB13,CDC23,GAR1,PSMB9,TRIM28,SERP1,ERC1,SOCS7,DDOST,PPP2R5A,JAK1,SEL1L,FTSJ1,PPA2,TRIM32,BEND3,B4GALT3,EYA2,CSNK1D,PRPF4B,OTUD5,MECP2,MANBA,B4GALT5,BABAM1,CDCA3,BRAP,CBLL1,SDF2L1,RAB11A,POFUT1,WWP2,CCNK,RFWD3,PTEN,ELP5,FUT8,PTPN11,AXIN2,FEM1B,COPS7B,MAP3K14,CREB1,OSTC,UBE2M,ZFP64,KAT2A,LONRF3,NEK7,ILF3,PARP4,FBXO9,TBRG4,ANAPC2,OTUD3,RHOT1,ARSK,MARK2,FBXO21,NUCB1,HGS,PRDX3,TTLL4,PPP1R11,DUSP11,DDB1,MIB2,CCNC,PIGM,UBE2E2,NOP2,NF1,DCAF15,KMT2E,MOGS,ALKBH5,DNAJC24,PTP4A3,UBE2Z,UBE2Q1,SIRT2,TAF6L,SNRPD3,USP48,FKBP2,MAPK14,BECN1,RNF103,MBD4,UBLCP1,CDC42,THADA,ATG3,METTL14,JOSD1,SLC35C2,OGG1,ARID4A,FGFR1OP2,CARM1,TIMM50,SRPK2,COPS8,TRIM8,DPM1,NCK1,VHL,RIOX2,WDR82,SUMF2,KMT2C,STK17B,MAN2A2,PAF1,UEVLD,PPM1G,BAZ1B,CAB39,STK11,CHEK2,ROCK1,GALNT10,COPS6,PSMC1,DCAF5,UBE2D3,PIGN,PPP1R12A,GORASP1,UFC1,MEF2A,RHBDD1,NUP205,DTL,MED10,PYURF,ZNF335,BCL2,ZRANB1,UBE3C,CSNK1G3,PSMA1,SYVN1,EIF2A,VKORC1,DAPK3,ISG15,CAND1,MASTL,GNAS,KLHL15,SIAH2,FN3KRP,NUP62,TRMT10B,NAA20,RBBP4,MBD1,PRKAB1,TOMM20,ASH1L,MPHOSPH8,WDYHV1,MDH2,NSD3,EXT2,CHD1,MEAF6,USP5,BABAM2,PPP6C,RPN2,PDIA6,ABI1,SCYL3,RLIM,PGGT1B,RNF25,METTL2A,PSMB7,PCGF6,OGDH,EDEM2,MBD3,BTBD1,DUS3L,TAB2,FKBP5,USP11,SMURF1,MAPK1,PPP2R2D,ABCA1,CBX4,PDF,SH2D3A,TRIP12,RAE1,EYA1,SHPRH,SCYL1,NUP54,DCUN1D4,MAN1A1,FASTKD3,FGFR3,KLHL20,GRK2,KMT5A,PPIG,DUS2,FBL,SLC35A1,TGFB1,B3GALT6,ZDHHC18,CSNK1G2,DCAF6,HEMK1,MIER1,PRKAR1B,RFFL,RCOR1,PRMT2,MEN1,CDK11A,MAPK3,MTMR3,DTX4,KBTBD7,KMT2B,MBD6,PLOD3,HRAS |
| 1.835e-21 | -47.75 | protein modification by small protein conjugation or removal | biological process | GO:0070647 | 998 | 264 | 17256 | 2622 |
NUP188,XIAP,CUL1,USP39,NHLRC3,UBE2I,FBXO22,PSMD1,RAD23B,FBXW2,NUP153,MARCH2,RNF26,SENP1,SEH1L,USP34,TOPORS,USP22,AURKB,DCUN1D5,CCNF,CBFB,SMAD2,RAD18,RPS27A,PSMD8,AXIN1,TPP2,OGT,KLHL42,FBXL3,SMAD1,ARRB2,ZNF598,AAAS,ZNF720,DDX58,WSB2,CLSPN,TOP2B,ZNRF3,PSMD9,CDC73,WDR48,DDRGK1,RNF121,KLHL5,RNFT1,ZNRF2,HDAC7,FBXO7,FBXL7,RNF135,NUP85,SOCS5,UBE2QL1,FOXK1,USP10,ADRB2,PSMB3,DERL1,EPOP,DCAF11,PIAS2,USP32,VCPIP1,YY1,RNF14,RNF139,NUP58,NDC1,TRIM41,ATXN3,SUZ12,UBR2,WDTC1,KLHL18,INO80E,STAM,ANKIB1,CCNA2,FBXL6,SIAH1,MTA1,UCHL5,UBA5,NUP107,SOCS6,ANAPC7,TTC3,RNF19A,MAVS,RNF169,CUL3,KIAA1586,ASB13,CDC23,PSMB9,TRIM28,SOCS7,PEX5,CDC16,NSMCE2,RNF38,TRIM32,DMWD,USP13,OTUD5,ZFP91,BABAM1,CDCA3,CBLL1,BRAP,UBE4A,WWP2,RFWD3,FBXO3,PSMD2,PTEN,HUWE1,AXIN2,LTN1,FEM1B,COPS7B,UBE3B,FBXL19,UBE2M,KAT2A,LONRF3,TNFAIP3,USP42,FBXO9,ANAPC2,OTUD3,RHOT1,ZNF862,FBXO21,KEAP1,HGS,PPP1R11,ANAPC4,DDB1,MIB2,UBE2E2,DCAF15,TRIM11,UBE2Q1,UBE2Z,USP48,BECN1,BIRC2,RNF103,ZER1,FANCL,NUP210,PCNA,CDC42,ATG3,JOSD1,ASB6,RYBP,SP3,COPS8,PLK1,TRIM8,RBX1,VHL,UBE2V1,BRCA1,USP21,PAF1,TRIM4,SOCS4,ARRDC1,ACTB,COPS6,DCAF5,PSMC1,RMND5A,UBE2D3,UFC1,ASXL2,NUP205,DTL,UBE2Q2,MED10,CCP110,MED8,PPIL2,CTR9,BCL2,ZRANB1,UBE3C,LRSAM1,DCAF8,PSMA1,RTF1,UBE4B,NFATC2IP,SYVN1,ISG15,CAND1,PSMC4,CDC27,KLHL15,SIAH2,NUP62,RNF114,USP7,CYLD,TOMM20,MPHOSPH8,TRAF7,SUMO2,USP5,RAD23A,BABAM2,MDM2,PSMA6,ABRAXAS2,SPSB3,PRPF19,RLIM,BIRC3,PSMA8,RNF25,PSMB7,PCGF6,NUP155,KDM1B,BTBD1,USP36,PSMD3,UHRF2,USP11,SMURF1,USP53,SMAD4,CBX4,ZC3HC1,TRIP12,KLHL21,RAE1,EYA1,SHPRH,NUP54,CDCA8,DCUN1D4,HERC3,KLHL20,RNF5,RHOA,DCAF6,PRKDC,RFFL,RANGAP1,PCGF1,FBXO41,BIRC5,DTX4,KBTBD7,USP20,MBD6,UBE2C |
| 1.920e-21 | -47.70 | HNRNPA1 (heterogeneous nuclear ribonucleoprotein A1) | protein interactions | 3178 | 534 | 174 | 17029 | 2761 |
COX15,HNRNPAB,MRPS15,XIAP,CUL1,SNRPD3,UBQLN2,UBE2I,SEC16A,MRPL19,PABPC4,PAPOLA,CDC42,EIF4A3,SRSF4,TRA2B,MRPL32,PCBP2,MRPL57,CARM1,SRPK2,CDC5L,SRP72,SNRNP200,VHL,MRPL43,HNRNPF,SREK1,WDR82,TOPORS,AURKB,BRCA1,MCM2,DHX15,RPS27A,MRPL27,PRPF4,ACTB,ROCK1,ARRB2,MRPL13,PDCD4,RPS15,MRPL9,EWSR1,MRPS2,PHB2,DHX9,MEF2A,PSMD9,SRRT,NUP205,LMNA,MCM5,RTCB,ZNF326,RBM3,MRPL48,MRPL21,PABPC1,DDX28,PRRC2A,SF3B6,SUGP2,MRPL16,PKM,MATR3,SF3A2,XRCC5,CAND1,SEC31A,SYNCRIP,QARS,RBMX,YWHAZ,ATP5F1A,CDK2,RNF14,HNRNPDL,ECPAS,MRPL3,CYLD,RPLP2,ARID2,IVNS1ABP,MRPL39,XAB2,UBR2,HNRNPUL2,MYH9,BCL2L1,SAFB2,SDHA,APP,PAIP2,ABHD16A,HNRNPA2B1,STRBP,DUT,AKAP8,MRPS27,RPAP1,TARDBP,AQR,RBM12B,STRAP,GM2A,CFL1,PRPF19,CSTF1,CDKN2AIP,CUL3,CIRBP,RPL38,GLO1,NFATC2,RAB1A,RPSA,EIF3H,SRSF1,DDX17,AFDN,DNAJC10,DAP3,HNRNPR,SAFB,H2AFX,RBMS1,FUS,PPP5C,H3F3A,PDCD11,SMURF1,ZC3HC1,SRSF6,NKRF,SHLD2,ATP5F1B,PNO1,GTF2F1,CAPN2,RPA2,GART,CLIC4,AHSA1,ANXA5,CARF,MRPL11,HNRNPM,YTHDC1,STAU1,PRKDC,LDHA,ILF3,MRPS10,PRMT2,RPL27A,PICALM,MARK2,PRDX1,ZFR,RPA1,DDX23,UPF1,HNRNPH3,LRPPRC,KHSRP,DDX5,DUSP11,PLOD3,ARHGAP23,CD81,PURA,HIPK3 |
| 2.034e-21 | -47.64 | PUJANA_BRCA2_PCC_NETWORK | MSigDB lists | PUJANA_BRCA2_PCC_NETWORK | 401 | 136 | 17377 | 2626 |
YTHDC2,CSNK2A1,KIF2C,CCNB1,UBE2I,FANCI,KIFC1,CDKN2C,PCNA,SIVA1,KIF22,CDC25B,MYBL1,DNMT1,SRSF10,SNRNP200,AATF,NCK1,RAD51AP1,SNRPB,MKI67,RRM2,WDHD1,ARHGDIB,CDC6,AURKB,BRCA1,SMC2,CCNF,MCM2,DHX15,CHAF1A,PRIM1,OGT,PRPF4,CHEK2,TFDP2,SSRP1,FUBP1,RECQL,MAPRE1,MRPL9,CENPF,RRM1,KIF23,CTCF,TTF1,SPAG5,CNOT3,NUP205,RB1,NFATC3,SMC3,MCM5,MSH2,TIMELESS,KNTC1,PIKFYVE,CPSF4,ABCC1,FDFT1,SRSF11,ZNF84,MYBL2,KCTD20,ITM2A,EXOSC9,NFATC2IP,XRCC5,CDC27,RBBP4,CCNB2,PTDSS1,TMEM106C,FOXM1,SUZ12,PTTG1,TPX2,SMARCA4,STMN1,VAV1,CCNA2,MDM2,KIF14,DUT,RNASEH2A,CSTF1,RFC3,POLR2G,HMGN4,DNAJC9,FRAT2,CDC23,H2AFV,TRIM28,EIF3H,MAT2A,RAD51C,ACYP1,H2AFX,XRCC3,ANP32E,PRPF4B,CASP6,RAE1,CDT1,TCF3,DBF4,BLM,SAC3D1,H2AFY,GTSE1,SMC4,GINS1,ELOVL5,HMGN1,NASP,PRKDC,BTAF1,ILF3,KIF11,DDX39A,SNRPA,CBX3,DDX23,RPA1,POLE,PFDN4,ZNF330,TFDP1,E2F1,HMGB2,SRSF3,IDH3B,UBE2C,ESPL1 |
| 2.845e-21 | -47.31 | MORF_AP2M1 | MSigDB lists | MORF_AP2M1 | 205 | 87 | 17377 | 2626 |
KARS,HNRNPAB,RAC1,SUMO2,COPE,ENSA,STARD7,AP1B1,UBE2I,DAZAP2,GNB2,SDHA,BCAP31,MBD4,SF3B2,HADHB,RPN2,PCBP2,CFL1,GPX4,SEC61B,POLR2L,SNRPB,PSMB7,GMFB,WBP2,TMEM147,RAB1A,RAB5B,RHEB,STOML2,DAP3,DDOST,PSMD8,ATP6V0C,PIEZO1,COPS6,FAU,PSMC1,AP2S1,MYL12B,CAPN1,SEPHS2,COX5B,MRPL9,PDAP1,NACA,DCTN2,COX4I1,SLC4A2,FKBP1A,DNAJC8,NDUFA2,HUWE1,ARPC5,ARF5,BANF1,CAPZA1,BUD31,CYC1,GNAI2,EEF1D,LYPLA2,TMED2,KDELR1,HMGN1,POLR2I,LDHA,RPL6,JTB,SSR2,COMMD4,EIF4G2,MAP2K2,CBX3,GNAS,SETD3,COX7A2L,COX8A,IMPDH1,SSNA1,YWHAZ,MDH1,GPI,IDH3B,PLOD3,PGAM1 |
| 2.845e-21 | -47.31 | MORF_RAC1 | MSigDB lists | MORF_RAC1 | 205 | 87 | 17377 | 2626 |
TMEM106C,KARS,HNRNPAB,RAF1,RAC1,SUMO2,ENSA,STARD7,SDHA,BCAP31,HNRNPA2B1,ATP2A2,MTA1,RAD23B,CS,HADHB,AHCYL1,GPX4,EBAG9,SP3,SNRNP200,SEC61B,DPM1,PPT1,GMFB,WBP2,TMEM147,RAB1A,RAB5B,PRPSAP1,SERP1,RHEB,ARF4,PSMD8,COX5A,CLN3,AP2S1,MYL12B,SMNDC1,SEPHS2,MRPL9,SEC61G,DAP,PDAP1,DCTN2,CYCS,SLC4A2,RAB6A,XPO7,AP3S1,COPB2,CNOT3,ARPC5,ARF5,SEC24C,BANF1,EI24,MEA1,CYC1,UBE3C,MAML1,ATP6V0D1,TMED2,KDELR1,NIPSNAP1,CSNK1G2,POLR2I,TSTA3,NSDHL,JTB,GORASP2,PICALM,MAP2K2,RPA1,YIF1A,PDCD6,PARG,COX7A2L,COX8A,GLG1,PGRMC1,PPP1R11,NUP62,MDH1,PLOD3,SSSCA1,DDB1 |
| 2.874e-21 | -47.30 | STAU1 (staufen double-stranded RNA binding protein 1) | protein interactions | 6780 | 350 | 129 | 17029 | 2761 |
HNRNPAB,COPA,MOGS,CUL1,CDIPT,OAT,CCNB1,BRIX1,PABPC4,SF3B2,KRR1,RAB8A,CDC42,EIF4A3,SRSF4,DNM2,LRRC59,FTSJ3,SRSF10,CDC5L,NOL12,SRP72,LARS,SNRNP200,HNRNPF,BRCA1,PRKRA,MCM2,SLC25A5,DHX15,ARF4,EIF3A,RPS14,ACTB,RRS1,ZMAT3,UBE2D3,PHB2,DHX9,RPL15,COPG2,RPN1,RBM34,YBX1,ALDH18A1,ATP6V0D1,PABPC1,LUC7L2,EEF1D,ACSL3,RPL6,GTPBP4,PKM,CYFIP2,MATR3,CAND1,EPRS,PCM1,SYNCRIP,GOLGA2,NSF,RBMX,QARS,ACLY,YWHAZ,ATP5F1A,PTDSS1,ZC3HAV1,SART1,CYLD,IVNS1ABP,SF3B1,RAC1,EIF3D,PCBP1,GLRX3,CPNE3,APP,HNRNPA2B1,IARS,TARDBP,RPL29,CCT2,NXT1,IDH3A,CUL3,NUP155,TRIM28,RPS9,DDX17,SRSF1,ATP1A1,DDOST,SEC61A1,HNRNPR,PSMD3,SAFB,TUBB,RPS2,NKRF,ARF1,ATP5F1B,AP3S1,KIF5B,PSMD2,RPL17,ARF5,RPL19,DDX31,HNRNPM,LDHB,SPTAN1,PPAN,STAU1,PRKDC,ZNF512,ILF3,LDHA,RPL8,ZFR,DDX23,HSPA1B,UPF1,HNRNPH3,LRPPRC,KHSRP,DDX5,GPATCH4,IFI16 |
| 3.126e-21 | -47.21 | ACEVEDO_LIVER_TUMOR_VS_NORMAL_ADJACENT_TISSUE_UP | MSigDB lists | ACEVEDO_LIVER_TUMOR_VS_NORMAL_ADJACENT_TISSUE_UP | 794 | 221 | 17377 | 2626 |
TMED7,PIGM,NAT9,H2AFZ,TMEM184B,MTX3,COPA,NDUFB6,TAP1,UBE2Q1,NANS,EIF1B,UBLCP1,SSR1,RPL23A,BCAT2,CDK5,ASAP2,EIF4A3,ATG3,IMPAD1,NUP153,RNF26,SPTSSA,TFG,DNMT1,CDC5L,USP34,LARS,NRAS,SNRPB,GMFB,PSMG1,MCFD2,PRPSAP1,ODC1,SLC50A1,LSG1,RAB22A,RHEB,ABHD5,EIF4ENIF1,MID1IP1,TMED10,STT3A,RPS27A,EIF2D,IARS2,MPV17,ATP6V0C,KPNA2,BTF3,RRS1,CLN3,CHPT1,ATP6V0E1,ZMAT3,C1orf74,HSPH1,MRPL9,MAPRE1,ZCCHC9,PPP1R2,SEC61G,UFC1,C16orf87,SDC2,RPL15,CTCF,HAUS4,MAN2B1,SLC35B1,PDCD7,METTL3,VPS25,NUP205,COPB2,LMNA,MCTS1,DTL,CD59,LYAR,SMC3,LRRC8D,DAD1,MCM5,RBM34,MEA1,TIMELESS,CTR9,KIFAP3,AHCY,MRPL48,MRPL40,PPA1,TERF2,VOPP1,NTPCR,PIGT,MAPKAPK3,NOA1,DHX29,RDH10,PIP4K2C,GTPBP4,GBA,C1orf35,SSR2,UBE4B,MTX1,EIF2A,PTTG1IP,MAP2K2,CCT8,EPRS,SERTAD2,GOLGA4,ACLY,FAM83D,NUP62,RUVBL2,TMEM14A,TSEN15,SNX27,CKLF,NDUFAF2,DYNLL1,TOR1AIP1,COPE,UCK2,LAGE3,RMI2,TWF2,GGPS1,ABHD16A,CRKL,CCNA2,ATP2A2,UCHL5,NUP107,MRPS27,RNASEH2A,TP53BP2,PDIA6,TMEM9,SAP30L,TMEM14C,CCT2,SEC61B,HMGN4,TIGD5,SLC26A6,FRAT2,DNAJC9,NUSAP1,BOLA1,NDUFA7,TMEM147,SERP1,AMZ2,PPP2R5A,DSN1,HNRNPR,DHX16,NSMCE2,CHCHD1,H2AFX,AP1S1,CANT1,FKBP5,USP11,PDCD2L,MIF4GD,GOLPH3L,RRP15,SCAMP3,CDK2AP2,VPS45,FLOT1,KLF13,SDF2L1,AP3S1,RMI1,WRB,BZW2,TFRC,XPR1,RRP36,SRXN1,PSMD2,KLHL20,PRC1,GEMIN6,YIF1B,TAGLN2,OSTC,CNPY3,MSH6,SPTAN1,TK1,ASPM,PARP4,LLPH,RAB3IP,FADD,HSPA1B,RPA1,HLA-B,C1orf131,MFAP1,SNAP29,BBX,TFDP1,HMGB2,TAF12,SRSF3,TATDN1,IGBP1,PURA,IPO4,VPS29 |
| 3.248e-21 | -47.18 | GO_REGULATION_OF_CELL_CYCLE | MSigDB lists | GO_REGULATION_OF_CELL_CYCLE | 907 | 244 | 17377 | 2626 |
CCNC,HECA,UBE2E2,PDCD6IP,GPR132,TSC2,THOC1,CUL1,CSNK2A1,SIRT2,CCNL2,CCNB1,BECN1,BIRC2,FANCI,PRNP,LIN9,CALM2,CDK5,DST,CDKN2C,PA2G4,PCNA,PSMD1,NEK6,CDC42,CDC25B,ECD,CARM1,MLST8,PTPRK,CDC37,SRPK2,CDC5L,PLK3,PLK1,BAK1,AATF,AKT2,LRP5,CDC6,AURKB,BRCA1,USP22,SOX4,CCNF,ANLN,RHEB,DOT1L,HHEX,RPS27A,PSMD8,E2F4,PPM1G,ITGB1,CAB39,STK11,ZNF268,CHEK2,VPS4A,TFDP2,E2F2,PSMC1,PDCD4,SLC25A33,CLSPN,GORASP1,PHB2,PRKAA1,CENPF,GADD45G,LAMTOR3,KIF23,CTCF,RACGAP1,TOP2B,CDK13,NOTCH2,EIF2AK4,PSMD9,CRLF3,CDC73,YY1AP1,JMY,SPAG5,CNOT3,DTL,TFAP4,RB1,PDXP,SMC3,CCP110,FBXO7,MSH2,BCL2,KNTC1,MCPH1,TERF2,MYBL2,GTPBP4,PSMA1,SRSF5,EIF4G2,PSMB3,RHOB,RBM38,DAPK3,PSMC4,MASTL,TSC1,CDC27,GOLGA2,DUSP3,CDCA5,FAM83D,CNOT6,ZNF830,RBBP4,CDK2,CCNB2,CABLES1,CDKN2A,BCCIP,ZNF207,CHMP2A,SART1,PRKAB1,CYLD,FOXM1,CAST,PTTG1,TPX2,RRAGC,SMARCA4,BCL2L1,ORC1,PRKACA,APP,MDM2,PSMA6,CCNA2,PIN1,KIF14,CDKN1B,TARDBP,ANAPC7,CABLES2,TP53BP2,ATF2,RPRD1B,CTDSP2,CDK12,HTRA2,PRPF19,PSRC1,BRD4,TIMP2,PSMA8,CDC123,PGGT1B,BTG2,CUL3,PSMB7,NUSAP1,PKMYT1,CDC23,RAB1A,CHMP2B,PSMB9,RAD51C,CDC16,RBL1,NSMCE2,HIPK2,PSMD3,GADD45B,ARNTL,UHRF2,XRCC3,CHMP4B,TRIM32,GAS2,GEN1,RAD51D,MIF,KIF3B,PKP4,KLHL21,TCF3,CDT1,CDK11B,BLM,ETS1,RAB11A,MAD2L2,FBXO5,RFWD3,RPA2,CCNK,PSMD2,PTEN,CENPJ,PTPN11,AXIN2,GTSE1,H2AFY,FEM1B,BRD7,CITED2,CNOT6L,STAT3,TGFB1,PPP1R9B,ADAM17,RHOA,TNFAIP3,HMGN5,ASPM,NEK7,PRKDC,TBRG4,ANAPC2,PRMT2,MEN1,BORA,KIF11,MACF1,CDK11A,SH3GLB1,MFN2,BIRC5,TFDP1,PML,E2F1,PKD2,NR2F2,TAF6,UBE2C,ESPL1,THAP5,TERF1,HRAS,ANAPC4,DDB1 |
| 3.570e-21 | -47.08 | nucleolus | cellular component | GO:0005730 | 959 | 251 | 18223 | 2701 |
DDX47,NOP2,MRPS15,KDM4A,NF1,SNX15,EBNA1BP2,SIRT2,UBE2I,BRIX1,RBM4,POLR3K,CUTC,RPL23A,KRR1,UBLCP1,UTP25,PA2G4,NOL11,EIF4A3,JAZF1,ETV6,POP7,NOC2L,RPF2,NUP153,TCEA1,MOB1A,ZNRD1,FTSJ3,SRPK2,NOL12,PLK3,METTL1,DEAF1,USO1,EXOSC6,AATF,BAZ2A,NOL8,NSUN2,RIOX2,MKI67,EZR,DDX20,CDC6,WDR82,SUPT20H,SMC2,UTP3,MCM2,MAK16,DHX15,EIF3A,UBTF,TIMM13,BRWD1,SPATA2,NIP7,RPS27A,CHD3,RPS14,RRS1,NMD3,ZMAT3,DDX42,CCDC137,SSRP1,EWSR1,ZCCHC9,TMUB1,HJURP,ZCCHC8,POLR2K,DHX9,CTCF,TOP2B,DNAJB1,RGS2,PARN,TTF1,YY1AP1,DDRGK1,TMEM179B,LYAR,DTL,DDX56,SUB1,EXOSC7,VMP1,RBM34,MDFIC,RBM3,GLE1,GEMIN4,EEF1D,EIF3L,DDX28,POLR2I,OXR1,TEX10,GTPBP4,RPS10,UTP15,EXOSC9,RTF1,SRSF5,METTL22,FXR1,PHF6,TWISTNB,RPL36,XRCC5,MAGED2,MBIP,CCDC86,SETD3,COX7A2L,PRMT7,DTD1,TCOF1,BTBD10,TSEN15,ZNF207,TRIM41,ATXN3,TRERF1,MPHOSPH8,URB2,SUZ12,OLA1,SMARCA4,ORC1,INO80E,CPNE3,SDHA,CHD1,RPAIN,MEAF6,RPL11,RRN3,MDM2,CD3EAP,NVL,UTP18,EXOSC1,AKAP8,TTC3,TOP1MT,CHTOP,UTP4,SAP30L,CDK12,MRM2,ACSL5,CDKN2AIP,RPL35,POLR2L,KAT7,NARF,CIRBP,SLBP,ATXN1,GORAB,NUSAP1,EDF1,PKMYT1,GAR1,RPS9,USP36,DDX17,NSA2,KIF2A,DSN1,DGCR8,LSM6,HNRNPR,TBL3,TULP3,CHCHD1,STAT1,BEND3,AKNA,PDCD11,COIL,ZNF146,NIFK,C19orf53,MCM10,RPS2,MIF4GD,ZFP91,RAE1,MRI1,HABP4,CDCA8,ARID5A,JMJD6,ABHD14B,NKRF,IP6K2,BLM,MAD2L2,DNAJB9,RRP36,PNO1,TUT4,SAPCD2,KRI1,H2AFY,DDX31,CARF,POLR1B,MAP3K14,FBL,MTX2,HNRNPM,RBM15B,PPAN,DDX24,PSPC1,PRKDC,WDR18,ILF3,LLPH,BMS1,PRMT2,DDX39A,KLF6,POLR2A,DDX23,UTP20,CDKN2AIPNL,L3MBTL3,ZNF330,ACOX1,CDCA7L,PITX1,PML,AEN,DUSP11,HMGB2,DDX5,ASNA1,RBPJ,MBD6,PARP10,TERF1,IFI16,BYSL,DDX52 |
| 3.593e-21 | -47.08 | HUWE1 (HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase) | protein interactions | 10075 | 469 | 158 | 17029 | 2761 |
MCCC1,PTP4A3,SND1,SNRPD3,OAT,SSR1,PAPOLA,PCNA,PSMD1,EIF4A3,ATG3,AP3S2,HADHB,CRY2,EIF5,CARMIL1,PCBP2,CDC5L,USO1,SNRNP200,DPM1,VHL,SNRPB,WDR82,MCL1,CDC6,BRCA1,MCM2,SLC25A5,SMAD2,PSMD8,RPS14,OGT,KPNA2,DVL1,PSMC1,HDAC2,UBE2D3,HSPH1,PHB2,UBXN1,NACA,RPL15,DNAJB1,NCKAP1,MYL6B,COPB2,SUB1,KLF16,EFTUD2,CAPZA1,AHCY,MAML1,LUC7L2,EEF1D,EIF5A,RB1CC1,C16orf72,RPS10,RPL6,PSMA1,RPS24,KRAS,SRSF5,PKM,KDM3A,CCT8,PSMC4,XRCC5,DERL1,EPRS,NAP1L1,MTHFD2,QARS,ACLY,PIAS2,VCPIP1,YWHAZ,GPI,RUVBL2,WIPI2,ATP5F1A,RBBP4,CDKN2A,USP7,RAF1,MDH2,OLA1,MYH9,PCBP1,STMN1,RAD23A,CRKL,CSDE1,HNRNPA2B1,PSMA6,ABRAXAS2,UCHL5,CS,PDIA6,RPRD1B,STRAP,PRPF19,CCT2,SHOC2,MAPRE2,IDH3A,CUL3,PSMB7,WBP2,DNAJA1,TRIM28,RPS9,SRSF1,ATP1A1,HSPA4,DDOST,PSMD3,STAT1,H2AFX,NCLN,TUBB,RAD51D,UNK,PDAP1,ARF1,ATP5F1B,TFRC,KIF5B,RPA2,PSMD2,DNAJC8,HUWE1,AHSA1,ANXA5,LDHB,NUDC,NASP,LDHA,ILF3,RPL8,TUFM,RFXANK,RANGAP1,RPL27A,MACF1,TARS,ECH1,MFN2,SLC25A19,KHSRP,ASNA1,SRSF3,NDUFS5,WDR91,YWHAH,DDB1,IFI16 |
| 3.737e-21 | -47.04 | MORF_ANP32B | MSigDB lists | MORF_ANP32B | 191 | 83 | 17377 | 2626 |
SART1,KARS,H2AFZ,HNRNPAB,RPLP2,SUMO2,COPE,STARD7,UBE2I,DAZAP2,GNB2,SDHA,PARK7,RAD23A,SF3B2,CALM2,PCNA,TARDBP,TCEA1,PCBP2,CCT2,SNRNP200,CDC123,SNRPB,PSMB7,RNPS1,VDAC2,AURKB,H2AFV,EIF3G,TRIM28,EIF3H,CLNS1A,EIF3K,HSPB11,HINT1,DDOST,RPS27A,PSMD8,PPM1G,UQCRH,BTF3,COPS6,FAU,PSMC1,COX5B,MRPL9,PHB2,PDAP1,NACA,CTCF,COX4I1,NDUFV1,BANF1,H2AFY,YBX1,CYC1,FBL,PABPC1,EEF1D,HMGN1,ILF3,TUFM,RPL6,JTB,RPS24,SSR2,EIF4H,COMMD4,DDX39A,EIF4G2,SF3A2,SNRPA,CBX3,GNAS,NAP1L1,RBMX,TATDN2,COX7A2L,YWHAZ,HMGB2,SRSF3,RBBP4 |
| 4.797e-21 | -46.79 | cellular component organization | biological process | GO:0016043 | 5372 | 1024 | 17256 | 2622 |
HEXB,TGOLN2,RPL23A,NAPG,DNAAF2,RAD23B,AP1M1,DNM2,RNF26,MRPL57,BAK1,ERCC1,RHOBTB3,NRAS,GABPA,EHMT1,WDHD1,MIER2,MCM2,RAB22A,ARF4,GINS4,AHNAK,MID1IP1,SMAD2,RPS27A,MYO18A,OGT,MPV17,SMAD1,SLC25A33,RHOC,MUM1,DHX9,RAB23,KCTD17,HAUS4,EIF2AK4,PSMD9,HAUS2,CDC73,ATG4A,TFAP4,CD59,PDXP,SMC3,MEGF8,FBXO7,GEMIN4,MRPL21,NUP85,NSUN4,PPP6R1,LUC7L2,IFRD1,MTA2,MTFR2,ERO1A,MAP7D1,MRPL16,MTX1,EIF4H,FNTA,KPNA1,WIPI2,ZNF830,CFAP20,RUFY3,MRPL3,NUP58,ALS2,RHOG,POC1A,PTTG1,ANK3,C5orf30,VTI1A,TPX2,INO80E,GLRX3,STMN1,REPS1,AHCTF1,SH3BP1,MTA1,CLCN6,NSFL1C,SEPT11,SNX8,CPNE1,ULK3,FAM118B,GOPC,KAT7,CRNKL1,RPL38,CIRBP,POLR2D,GORAB,RAB1A,TANC1,MAT2A,PPP2CA,KIF2A,NSMCE2,CORO1C,CAMKMT,SNRPG,PPP5C,PITRM1,TUBB,MZT1,SRSF6,CCM2,FLOT1,ATG2B,ATP5F1B,WDR5,IFT27,SAPCD2,GOLM1,RPA2,PDCD10,CLIC4,ITGB8,HUWE1,NAA50,KANSL2,NAP1L4,GTF2H2,SPTAN1,TCTEX1D2,TACC1,HEBP2,LLPH,RAB3IP,PICALM,SSNA1,WDR45B,YWHAH,PRNP,TET3,RAB8A,NUP210,TIMM23,NOC2L,EIF5,MTPN,TACC3,RYBP,PLK1,SEPT9,CELSR2,RBX1,SNRPB,PSMG1,PBRM1,UTP3,LUC7L,USP21,TRIM4,TRAM2,CHD3,GRIPAP1,E2F4,DVL1,CLN3,POT1,NUMB,HJURP,PHB2,CENPF,NKD2,SDC2,KLC1,CHCHD2,NCKAP1,ARID1B,CCP110,MBD2,SSBP3,XPA,ARL6IP1,CTR9,MRPL48,ACSL3,LDB1,CAMSAP1,ICAM2,BBS12,HAUS8,MBIP,PCM1,LAMTOR4,RUVBL2,MYO9A,ECPAS,CCNB2,UNC13C,BCCIP,USP7,SART1,ARID2,NDUFAF2,TOR1AIP1,SLC2A1,ATP6V1B2,LYN,OIP5,MRPL50,VAV1,NRF1,BRPF3,KMT5C,ABRAXAS2,PIN1,TARDBP,LMAN1,TOP1MT,STRAP,PRPF19,PPIF,KDM3B,ARHGAP17,MND1,CLCN3,BIRC3,PPT1,RAB7A,NUP155,DCLRE1C,CHMP2B,MRPS14,AFDN,IDE,RBL1,UBXN2B,CHMP4B,XRCC3,H3F3A,SMAD4,RAD51D,PARD3,NIFK,UNK,MTERF1,AGO2,CDCA8,HMGN3,ARF1,SLC12A9,NCAPG,TUBGCP2,CTSS,POLR1B,ORC3,YTHDC1,PPAN,ACP2,RHOA,HMGN5,PRKDC,TOP3A,RANGAP1,PCGF1,DDX23,RAB18,CACNB1,SEC23IP,PDCD6,NEK1,ATP6V1D,L3MBTL3,E2F1,TAF12,NUP188,MAX,H2AFZ,PDCD6IP,ADAM10,CXXC1,CUL1,USP39,OAT,PARK7,MTFR1L,TRA2B,AP2B1,TAF5L,CISD2,SMARCE1,SRSF10,SGCE,USP22,RFC2,CLNS1A,EIF3A,PRIM1,ZMYM3,DOT1L,HHEX,WAS,KIF18B,BRD2,RPS14,LUC7L3,MRPL27,MAP4,PTPDC1,RECQL,DHPS,PRKAA1,VAV2,GSPT2,RRM1,DNAAF5,B4GALT1,CYCS,SUPT7L,PRPF39,PSEN1,TMEM165,VPS25,NDUFS7,NPLOC4,SPAG5,RTKN,TMEM250,ARPC5,MSH2,FBXL7,MRPL40,TNRC18,SYTL3,GCC2,PRIM2,WDR1,GORASP2,ARID1A,CAPZA2,ADRB2,GOSR1,MTR,CCT8,XRCC5,PI4K2A,DERL1,CAT,SEC31A,GOLGA2,EPOP,RBMX,ARAP1,CABIN1,CDKN2A,NDC1,ATXN3,REPS2,RAF1,POMP,BCL2L1,DECR1,CCNA2,SIAH1,MRPS27,TAP2,TP53BP2,CFL1,SAP30,ANKLE2,BRD4,CDC123,LRRC8A,ELP4,SERP1,TRIM28,EML4,SUPT16H,RAD51C,CHMP4A,DSN1,SAFB,BEND3,EYA2,DYNC1LI2,NDUFS1,MECP2,SPDL1,HMG20A,SLC25A36,NDUFA2,PTPN11,AXIN2,MRPL54,CNN2,NDUFA3,MTX2,MSH6,KAT2A,TMEM126B,RABIF,ADSL,MACF1,KIF11,FADD,SH3GLB1,CBX3,INF2,TMEM127,NDUFS5,WDR62,TAF6,ESPL1,PURA,DDB1,IPO4,POLA2,MTX3,KMT2E,UQCR10,BRIX1,MAP1LC3B,ATP5PF,MRPL19,DST,CDC42,SYNM,RAB35,RPF2,CARMIL1,CARM1,SRPK2,LARS,SNRNP200,NCK1,VHL,RIOX2,TMEM216,PITPNB,KMT2C,ASF1B,HSPB11,BRWD1,NIP7,MIA2,CAB39,BAZ1B,STK11,CHEK2,CLU,VPS4A,MRPL13,ATP6V0E1,CAPN1,PPP1R12A,GORASP1,EPN1,PRPF18,NUP205,TENM3,ZRANB1,MCPH1,SLC12A2,ATP6V0D1,ATP5IF1,RPL6,GBA,EIF2A,DAPK3,MASTL,SIAH2,SLC16A1,YWHAZ,EHD4,TMEM14A,CHMP2A,PRKAB1,CORO7,FEZ2,SMARCA4,HNRNPA2B1,RRN3,UBXN2A,KIF14,PPP6C,CLTB,CHP1,PCGF6,BICD2,CADM1,MBD3,SURF4,HPS5,ANP32E,MAPK1,BRD9,ABCA1,TMEM33,DNAJC2,GCLM,SHPRH,RAE1,DCTN2,NUP54,PAWR,GFM2,FERMT3,KIF5B,FASTKD3,KLHL20,KMT5A,SEC24C,H2AFY,ARHGEF2,ANP32A,ATG13,NDUFS8,FBL,STAT3,MICAL3,MYO5A,TGFB1,COA3,PPP1R9B,TIMMDC1,HELB,MIER1,ATP2C1,COG1,RCOR1,PRMT2,TFEB,LEMD2,CTSL,UPF1,ELMO1,KMT2B,ACAT1,CENPT,ZMIZ1,PLOD3,HRAS,TERF1,FGFR1OP,RAB14,TMED7,ADD1,MRPS15,KDM4A,XIAP,GLUD1,CNTROB,MIS12,CDK5,NEK6,PDS5B,NUP153,MLST8,PLK3,MRPL43,TOPORS,MCL1,SMC2,STOML2,BRMS1,AXIN1,LIMK1,VIPAS39,ATP6V0C,TFDP2,LONP2,AAAS,SSRP1,NDUFV2,MRPL9,PHF23,MRPS2,TOP2B,TMED3,EZH1,ITGB5,LMNA,MCTS1,NAGPA,TIMM8B,CYFIP1,RB1CC1,TSPYL4,ZMYND11,MYBL2,RPS10,SRSF5,NCDN,RHOB,PTPRF,SCARB2,CSK,TEX30,SETD3,NDE1,SNX14,SGF29,ZNF207,ANKRD27,UBR2,ACTR3,CHD1L,WDTC1,MYH9,NUF2,EFL1,PRKACA,APP,STAM,RAB21,CLUAP1,SP100,ATP2A2,NUP107,CEP63,RNF19A,CLN6,ATF2,ATP6V1G1,DCTN1,PSRC1,MAP4K4,INTS13,ATP6V0A1,NUSAP1,NDUFA7,TAZ,CHCHD3,TAF2,PEX5,SEC61A1,HIPK2,ANXA6,TRAK1,JMJD6,AKT1S1,ETS1,WRB,CAPN2,ADD3,SUV39H2,NDUFB4,PRDM4,GEMIN6,SGCB,LYPLA2,S100A6,NUDC,PDPK1,TK1,TNFAIP3,JTB,EMP3,MRPS10,RPA1,KIF18A,POLE,CCDC6,PML,HMGB2,SNAPIN,COX15,AGRN,MCCC1,S1PR2,SEC16A,BIRC2,ATPAF1,DLG5,PCNA,XRCC2,ETV6,ZFYVE27,MYBL1,MCMBP,MRPL32,PTPRK,BAZ2A,TLK1,MRPL12,GMFB,EZR,LNX2,LRP5,BRCA1,ANLN,RAB5B,STX16,DPYSL3,EPB41,OPTN,TIMM13,SEPT1,NAGLU,ACTB,C2CD5,NAA60,GEMIN7,CTCF,RACGAP1,PPP3CB,RLF,RAPGEF6,RB1,VASP,VMP1,ABCC1,PREB,TRAPPC9,RTF1,KRAS,UBE4B,ARPC1A,GOLGA4,SNAP23,TBPL1,PRMT7,ATP5F1A,KCTD7,NDUFA5,CYLD,XAB2,DYNLL1,MRPL39,RPL11,ATP6V0B,MDM2,MRPL34,CORO1A,SAP30L,DVL2,TIMP2,BTG2,TUBGCP5,FRAT2,PRPF3,KDM1B,TXNL4A,USP36,RPSA,SRSF1,MRPL2,TIMM17A,CEP55,NDUFA11,NCOA1,AP2S1,CTDP1,CDT1,ARFIP2,SMC6,CSNK1A1,TFRC,IRF4,STARD9,NDUFV1,ABCD1,SS18L1,PTGES3,CENPM,CAMK2G,SNX2,ZMYM5,RHOT2,CHCHD6,BIRC5,SNAP29,PKD2,UBE2C,CHMP7,NDUFB6,ZDHHC8,TAP1,PLXNA1,CCNB1,KIFC1,SNUPN,DBNDD1,MAST2,CDC25B,TFG,DNMT1,SEH1L,USO1,ATG9A,AKT2,DDX20,AURKB,MCFD2,FOXRED1,SLC25A5,TMED10,PSMD8,EIF2D,ITGB1,RRS1,ARRB2,RTN3,HDAC2,LIME1,MAPRE1,GMFG,KIF23,PMF1,METTL3,JMY,NDUFS4,CFLAR,FKBP1A,NDUFAF6,SNX18,HDAC7,ATP6V0A2,PIKFYVE,TMED2,TERF2,DDX28,SIGMAR1,SEPT8,PLEC,TOMM40,CYFIP2,PKM,KDM3A,SF3A2,PATL1,FAS,EPRS,NSF,PPP3R1,VCPIP1,PPP6R3,YY1,CDK2,DNMT3A,TRIP10,SUZ12,SF3B1,RAC1,EIF3D,MOAP1,TERF2IP,KDM2A,SHC1,GPX4,CCT2,RFC3,MKLN1,TAOK1,CUL3,CDC23,GAR1,H2AFV,POLG2,CENPU,HSPA4,MRPL55,GOLGA8A,H2AFX,TRIM32,ATMIN,CSNK1D,POLQ,PKP4,TWNK,BABAM1,BLM,RAB11A,MAD2L2,PIP5K1C,PTEN,CENPJ,PRC1,COPS7B,CREB1,IFT46,PACS2,SMC4,ZFP64,STRIP1,NEK7,WDR18,ANAPC2,RHOT1,MARK2,HGS,PRDX3,ATP5MC3,TFDP1,STX18,CCDC69,NAXE,BRWD3,NPHP4,NOP2,ST13,PLXNC1,NF1,UBN1,AGFG1,SIRT2,TAF6L,KIF2C,SNRPD3,BECN1,MAPK14,CUTC,EDC3,RAP1A,DPYSL2,ZNHIT6,ATG3,KHDC4,NDUFB9,KIF22,NFU1,RP2,ARID4A,ELOF1,TIMM50,COPS8,FOPNL,WDR82,CHAF1A,UBTF,GEMIN5,PAF1,TIMM29,PQBP1,ATXN2L,ROCK1,COPS6,SASS6,STARD3NL,SLC12A7,RPS15,TM9SF4,CIB1,MEF2A,BANF1,ZNF335,CAPZA1,GLTP,BCL2,KIFAP3,KNTC1,HP1BP3,SEPT7,CAND1,TSC1,NAP1L1,ODF2,CDCA5,PITPNA,NUP62,RBBP4,PDSS2,SMARCD1,MBD1,WASF2,ASH1L,IMMT,TOMM20,FAM92A,PLAGL2,NSD3,TWF2,CHD1,MEAF6,MIEF1,ANKRD28,ANKLE1,FARSA,BABAM2,SAR1A,AKAP8,APOOL,F2R,ABI1,HTRA2,FAM172A,DMAC2,WIPF1,TOR1AIP2,ERBIN,NDUFB1,PEF1,RAD54B,DAP3,CHCHD1,SCARB1,REEP4,SMURF1,PPP2R2D,CBX4,MIF,KIF3B,MRPL42,GOLPH3L,EYA1,SRGN,MRPS26,TIMM21,FBXO5,PELO,MRPL11,TTC17,GINS1,TELO2,HMGN1,NASP,ASPM,WDR81,ATP5MF,MEN1,MFN2,MAPK3,ATAD2,ATP6V1C1 |
| 4.872e-21 | -46.77 | MODULE_98 | MSigDB lists | MODULE_98 | 383 | 131 | 17377 | 2626 |
H2AFZ,THOC1,AP3M2,CSNK2A1,KIF2C,AGFG1,CCNB1,MAPK14,MBD4,CDKN2C,PCNA,ASAP2,POP7,TRA2B,KIF22,NUP153,DNMT1,SRSF10,SRPK2,CDC5L,PLK1,COPS8,VHL,HNRNPF,SMC2,NUTF2,SOX4,RFC2,CBFB,CHAF1A,PRIM1,BRD2,PSMD8,SMAD1,HDAC2,SSRP1,EWSR1,POLR2K,CENPF,DHX9,CTCF,KIF23,MSH2,YBX1,KNTC1,SRSF11,PRIM2,MAPKAPK3,MYBL2,PTTG1IP,PSMC4,XRCC5,NAP1L1,KPNA1,POLR2J,DCK,CEBPG,YY1,RBBP4,CDK2,CCNB2,CDKN2A,ADNP2,ZBTB24,TCF12,FOXM1,PTTG1,ORC1,PCBP1,RAD23A,HNRNPA2B1,APLP2,NRF1,CCNA2,MTA1,PIN1,NUP107,ATF2,SAP30,RFC3,HMGN4,POLR2D,PSMB7,E2F3,SLBP,DDX17,SRSF1,RAD51C,HNRNPR,TULP3,STK38,SAFB,H2AFX,STAT1,FKBP5,XRCC3,SNRPG,COIL,LRP8,ZNF146,RAD51D,CBX4,PRPF4B,SRSF6,BLM,RPA2,PSMD2,ARF5,PPP1R8,ANP32A,NAP1L4,CITED2,FBL,HMGN1,NASP,PRKDC,ILF3,KLF6,SNRPA,DDX23,RPA1,POLE,TFDP1,E2F1,KHSRP,DDX5,HMGB2,SRSF3,NR2F2,TAF6,ESPL1 |
| 4.878e-21 | -46.77 | regulation of cellular catabolic process | biological process | GO:0031329 | 812 | 225 | 17256 | 2622 |
NUP188,TSC2,KDM4A,YTHDF3,SIRT2,UBQLN2,MAPK14,BECN1,RIC1,PARK7,TRIM65,FBXO22,PABPC4,CDK5,ABL2,RAB8A,PSMD1,NUP210,METTL14,PIK3R2,RAD23B,NUP153,CISD2,ECD,SENP1,DRAM2,SEH1L,MLST8,RYBP,CDC37,WDR41,PLK1,PLK3,LARS,TRIM8,EXOSC6,RBX1,AKT2,PBK,EZR,MCL1,RHEB,OPTN,ABHD5,RPS27A,PSMD8,AXIN1,SOCS4,OGT,ADAM9,ATP6V0C,STK11,RNASEL,CLU,DVL1,ROCK1,PSMC1,ATP6V0E1,LONP2,AAAS,CAPN1,SVIP,TBC1D12,SCOC,PHF23,UBXN1,PRKAA1,NKD2,DHX9,LAMTOR3,EIF2AK4,THRAP3,PSMD9,PARN,PSEN1,METTL3,NUP205,DDRGK1,EXOSC7,TIGAR,FBXO7,DAPK1,ATP6V0A2,BCL2,YBX1,PIKFYVE,LRSAM1,ATP6V0D1,NUP85,PABPC1,PHKG2,SOCS5,ATP5IF1,RB1CC1,GBA,PIP4K2C,USP10,PSMA1,EXOSC9,ADRB2,PTTG1IP,FXR1,EIF4G2,DAPK3,PSMB3,RMC1,PSMC4,TSC1,HSPBP1,SYNCRIP,GOLGA2,LAMTOR4,EXOC4,NUP62,YWHAZ,CTSA,SNRNP70,RNF14,TOB1,RNF139,NUP58,ZC3HAV1,EGLN1,RNF114,USP7,NDC1,PRKAB1,ATXN3,FEZ2,SUMO2,RRAGC,ATP6V1B2,PRKACA,ANKIB1,BCAP31,EPM2A,PAIP1,RPL11,RAD23A,USP5,ATP6V0B,PSMA6,MDM2,RALB,UCHL5,TBC1D14,DDA1,EXOSC1,NUP107,TARDBP,RNF19A,HTRA2,PDCL3,ATP6V1G1,UBQLN4,ULK3,TIMP2,POLR2G,PSMA8,BTG2,PSMB7,CIRBP,PFKFB3,ATP6V0A1,NUP155,EDEM2,VDAC1,PSMB9,USP36,CHMP4A,VPS26B,TAB2,HNRNPR,PSMD3,HIPK2,CHMP4B,TICAM1,SCARB1,SMURF1,CSNK1D,USP13,DAP,RAE1,AGO2,NUP54,SECISBP2,CSNK1A1,PIP4K2A,FASTKD3,PPP1R3B,PSMD2,PTEN,AXIN2,DCP1A,ANP32A,ATG13,CNOT6L,STAT3,TPCN1,RNF5,SAMD4B,LONRF3,TNFAIP3,TBRG4,SH3GLB1,MAPK3,MFN2,TFEB,HSPA1B,MTMR3,GNA12,KEAP1,ATP6V1D,UPF1,LRPPRC,E2F1,PML,KHSRP,PSAP,ATP6V1C1,WDR91,CD81,PGAM1,VPS29,IFI16 |
| 5.100e-21 | -46.73 | GO_CELL_DIVISION | MSigDB lists | GO_CELL_DIVISION | 435 | 143 | 17377 | 2626 |
SKA3,PDCD6IP,ENSA,USP39,KIF2C,SIRT2,CNTROB,CCNB1,UBE2I,BECN1,MIS12,KIFC1,CDK5,NEK6,RAB35,PDS5B,CDC25B,MCMBP,SEH1L,PLK1,AATF,SEPT9,NSUN2,CDC6,AURKB,SMC2,CCNF,ANLN,SEPT1,KIF18B,MAP4,VPS4A,CHEK2,ANXA11,NUMB,MAPRE1,RHOC,CENPF,CIB1,KIF23,RACGAP1,HAUS4,PMF1,HAUS2,SPAG5,RB1,SMC3,SNX18,TIMELESS,FBXL7,KNTC1,GNAI2,SEPT7,RHOB,DAPK3,HAUS8,MASTL,GOLGA2,CDCA5,FAM83D,NDE1,ZNF830,CDK2,CCNB2,CABLES1,CDKN2A,ZNF207,CHMP2A,PTTG1,ANK3,ACTR3,TPX2,MYH9,NUF2,BCL2L1,STMN1,OIP5,AHCTF1,CCNA2,RALB,KIF14,SEPT11,ANAPC7,CABLES2,CEP63,ANKLE2,PSRC1,MAPRE2,CDC123,CUL3,CDCA2,NUSAP1,CHMP2B,CDC23,TXNL4A,KIF2A,CHMP4A,CDC16,DSN1,NSMCE2,CEP55,CHMP4B,REEP4,PPP2R2D,PARD3,TUBB,ZC3HC1,POU3F2,CTDP1,KLHL21,BABAM1,CDCA8,CDCA3,NCAPG,CSNK1A1,RAB11A,MAD2L2,SAC3D1,FBXO5,CCNK,CENPJ,PELO,PRC1,ARHGEF2,NUDC,SMC4,RHOA,TACC1,ASPM,NEK7,JTB,ANAPC2,KIF11,BORA,NEK1,BIRC5,CENPT,UBE2C,CHMP7,ESPL1,TERF1,ANAPC4,SSSCA1 |
| 5.275e-21 | -46.69 | RPA1 (replication protein A1) | protein interactions | 6117 | 479 | 160 | 17029 | 2761 |
RAB14,HNRNPAB,ADD1,COPA,THOC1,YTHDF3,CUL1,CCNB1,RBM4,PABPC4,SF3B2,RAB8A,PCNA,RAB35,INTS1,RAD23B,AP2B1,KCNAB2,SEH1L,CDC5L,ERCC1,SNRNP200,SNRPB,NSUN2,HNRNPF,WDHD1,WDR82,BRCA1,SMC2,ESYT1,DIDO1,MCM2,RFC2,DHX15,CHAF1A,PRIM1,GEMIN5,AHNAK,MAP4,U2SURP,ITGB1,ACTB,ARRB2,ZNF598,FUBP1,RECQL,PARP12,EWSR1,PPP1R12A,ZCCHC8,CHTF18,UBXN1,DHX9,RPL15,TOP2B,RAB6A,LMNA,SMC3,EXOSC7,EIF2S2,EFTUD2,XPA,CAPZA1,MSH2,RBM3,GEMIN4,MCPH1,ATP6V0D1,PABPC1,TERF2,NTPCR,RB1CC1,PRRC2A,TEX10,RPL6,MPG,MATR3,XRCC5,DERL1,EPRS,PFDN5,SYNCRIP,RBM25,TCOF1,RUVBL2,CDK2,HNRNPDL,USP7,CHERP,RAB11B,SF3B1,ACTR3,CHD1L,TPX2,MYH9,AP1B1,BCAP31,RPAIN,HNRNPA2B1,RBM23,CCNA2,STRBP,PPME1,AKAP8,TARDBP,RBM15,RPRD1B,PRPF19,CDKN2AIP,RFC3,RAB7A,DNAJC9,NFATC2,RAB1A,TRIM28,RPS9,DDX17,PPP2CA,HNRNPR,CORO1C,UHRF2,FUS,TUBB,TMEM33,SCAMP3,TRIP12,EYA1,BLM,CSNK1A1,RMI1,TFRC,RPA2,RFWD3,ARHGEF2,LTN1,RPL19,TAGLN2,POLR1B,FBL,HNRNPM,SMC4,SPTAN1,TK1,POLK,PRKDC,HELB,LDHA,TOP3A,ILF3,SYMPK,PRDX1,POLR2A,ZFR,RPA1,MYO1F,DDX23,BBX,PGRMC1,DDX5,DDB1 |
| 5.303e-21 | -46.69 | protein-containing complex subunit organization | biological process | GO:0043933 | 1786 | 413 | 17256 | 2622 |
MAX,PDCD6IP,NDUFB6,MRPS15,ZDHHC8,CUL1,USP39,CCNB1,OAT,MIS12,RPL23A,NAPG,SNUPN,DNAAF2,RAD23B,DNM2,TRA2B,AP2B1,NUP153,TFG,SMARCE1,SEH1L,MRPL57,SRSF10,USO1,MRPL43,DDX20,SMC2,MCFD2,MCM2,FOXRED1,CLNS1A,EIF3A,STOML2,AHNAK,WAS,MID1IP1,SMAD2,BRD2,KIF18B,TMED10,RPS27A,PSMD8,RPS14,LUC7L3,AXIN1,MRPL27,EIF2D,VIPAS39,RRS1,SMAD1,SLC25A33,NDUFV2,MRPL9,LIME1,MRPS2,DHPS,GSPT2,PRKAA1,DHX9,RRM1,DNAAF5,KCTD17,B4GALT1,PRPF39,PSMD9,CDC73,NDUFS7,MCTS1,NDUFS4,NDUFAF6,CD59,TFAP4,TMEM250,FKBP1A,ATP6V0A2,FBXL7,MRPL40,GEMIN4,MRPL21,NSUN4,PPP6R1,LUC7L2,TMED2,DDX28,SIGMAR1,TSPYL4,WDR1,RPS10,SEPT8,MRPL16,ARID1A,CAPZA2,SRSF5,ADRB2,PKM,EIF4H,PATL1,SF3A2,CCT8,FAS,DERL1,CAT,SEC31A,EPRS,GOLGA2,NSF,RBMX,CABIN1,WIPI2,NDE1,PPP6R3,SNX14,NUP58,MRPL3,ZNF207,NDC1,REPS2,SF3B1,RAF1,EIF3D,CHD1L,RAC1,NUF2,POMP,EFL1,PRKACA,STMN1,DECR1,AHCTF1,NUP107,MRPS27,SEPT11,CFL1,GPX4,CCT2,CDC123,GOPC,CRNKL1,RPL38,POLR2D,CUL3,CIRBP,ATP6V0A1,NDUFA7,RAB1A,TAZ,TRIM28,MAT2A,CENPU,SUPT16H,TAF2,KIF2A,RAD51C,CHMP4A,HSPA4,MRPL55,H2AFX,SNRPG,BEND3,PPP5C,CSNK1D,DYNC1LI2,POLQ,MZT1,NDUFS1,ANXA6,SRSF6,TWNK,FLOT1,BLM,RPA2,NDUFA2,NDUFB4,CENPJ,AXIN2,MRPL54,GEMIN6,NAP1L4,NDUFA3,GTF2H2,SMC4,TK1,TNFAIP3,TMEM126B,WDR18,MRPS10,ADSL,PICALM,FADD,SH3GLB1,RPA1,KIF18A,PML,NAXE,HMGB2,NDUFS5,TAF6,DDB1,IPO4,SNAPIN,COX15,NOP2,ST13,UBN1,NF1,UQCR10,MCCC1,KIF2C,TAF6L,SNRPD3,BRIX1,MAP1LC3B,SEC16A,CUTC,MRPL19,ATPAF1,EDC3,PRNP,DLG5,ZNHIT6,XRCC2,RPF2,KHDC4,NDUFB9,EIF5,MRPL32,SRPK2,COPS8,SNRNP200,SEPT9,RBX1,NCK1,BAZ2A,SNRPB,MRPL12,PSMG1,LNX2,LRP5,PBRM1,ANLN,LUC7L,ASF1B,CHAF1A,DPYSL3,EPB41,TRIM4,GEMIN5,UBTF,PAF1,SEPT1,NIP7,MIA2,ATXN2L,CAB39,STK11,CLU,VPS4A,DVL1,CLN3,MRPL13,NAA60,GEMIN7,RPS15,HJURP,GORASP1,TM9SF4,CENPF,KLC1,CTCF,NUP205,PRPF18,VASP,MBD2,SSBP3,XPA,CAPZA1,KIFAP3,KNTC1,MRPL48,PREB,HP1BP3,ATP5IF1,TRAPPC9,ACSL3,RPL6,EIF2A,SEPT7,BBS12,CAND1,TSC1,NAP1L1,SNAP23,PRMT7,RUVBL2,EHD4,RBBP4,ECPAS,UNC13C,PDSS2,SMARCD1,KCTD7,SART1,CHMP2A,NDUFA5,PRKAB1,CORO7,TOMM20,CYLD,ARID2,NDUFAF2,MRPL39,XAB2,SLC2A1,SMARCA4,PLAGL2,TWF2,RPL11,OIP5,ANKRD28,MRPL50,FARSA,RRN3,MDM2,SAR1A,PIN1,KIF14,PPP6C,MRPL34,LMAN1,CLTB,STRAP,HTRA2,DVL2,CHP1,PRPF19,DMAC2,TUBGCP5,FRAT2,WIPF1,PRPF3,NDUFB1,CHMP2B,TXNL4A,MRPS14,PEF1,RPSA,SRSF1,MRPL2,DAP3,IDE,CHCHD1,NDUFA11,ANP32E,CHMP4B,XRCC3,SCARB1,H3F3A,AP2S1,SMAD4,ABCA1,PARD3,RAD51D,TMEM33,MIF,NIFK,MRPL42,SHPRH,CDT1,AGO2,NUP54,MRPS26,TIMM21,CSNK1A1,GFM2,TUBGCP2,FBXO5,FERMT3,KIF5B,FASTKD3,NDUFV1,SEC24C,PELO,H2AFY,ANP32A,NDUFS8,CENPM,PTGES3,ORC3,TTC17,MRPL11,CAMK2G,MICAL3,YTHDC1,TGFB1,PPAN,COA3,NASP,SNX2,TIMMDC1,MEN1,MAPK3,DDX23,SEC23IP,PDCD6,SNAP29,ACAT1,PKD2,CENPT,TAF12,PLOD3,UBE2C,CHMP7 |
| 6.083e-21 | -46.55 | Processing of Capped Intron-Containing Pre-mRNA | REACTOME pathways | R-HSA-72203 | 247 | 102 | 10287 | 1696 |
SART1,NDC1,SARNP,NUP188,THOC1,CHERP,XAB2,SF3B1,RBM8A,USP39,SNRPD3,PCBP1,PAPOLA,SF3B2,HNRNPA2B1,NUP210,EIF4A3,METTL14,SRSF4,NUP107,TRA2B,NUP153,AQR,CHTOP,CCAR1,PCBP2,SEH1L,SRSF10,CSTF1,PRPF19,CDC5L,FYTTD1,SNRNP200,NXT1,POLR2G,POLR2L,SNRPB,PPIE,CRNKL1,RNPS1,HNRNPF,POLR2D,SLBP,LSM8,NUP155,PRPF3,TXNL4A,DHX15,SRSF1,SUGP1,HNRNPR,LSM6,DHX16,U2SURP,PQBP1,PRPF4,FUS,SNRPG,AAAS,SMNDC1,DDX42,CWC25,CDC40,POLR2K,SRSF6,RAE1,NUP54,DHX9,PDCD7,METTL3,SRRT,NUP205,GTF2F1,RBM17,SNRNP25,DNAJC8,CTNNBL1,CWC27,EFTUD2,BUD31,YBX1,CPSF4,NUP85,HNRNPM,SRSF11,POLR2I,SF3B6,SRSF5,PPWD1,DDX39A,SYMPK,SF3A2,SNRPA,POLR2A,DDX23,POLR2J,RBMX,NUP62,DDX5,SRSF3,SNRNP70,NUP58 |
| 6.788e-21 | -46.44 | GO_REGULATION_OF_CATABOLIC_PROCESS | MSigDB lists | GO_REGULATION_OF_CATABOLIC_PROCESS | 707 | 202 | 17377 | 2626 |
KDM4A,ZDHHC8,CUL1,CSNK2A1,SIRT2,UBQLN2,CCNB1,MAP1LC3B,BECN1,PARK7,TRIM65,FBXO22,CDK5,ABL2,PSMD1,CDC42,PIK3R2,RAD23B,CISD2,ECD,TIPARP,SENP1,DRAM2,PLK3,PLK1,TRIM8,AKT2,PBK,EZR,ODC1,ABHD5,RPS27A,PSMD8,AXIN1,ITGB1,SOCS4,OGT,ADAM9,ATP6V0C,STK11,ZNF268,CLU,CHEK2,DVL1,CLN3,PSMC1,OAZ1,LONP2,ATP6V0E1,CAPN1,SVIP,TBC1D12,SCOC,GORASP1,GGA1,PHF23,DNAJB2,UBXN1,PRKAA1,CENPF,NKD2,EIF2AK4,PSEN1,PSMD9,RHBDD1,DDRGK1,RB1,VMP1,DAPK1,ATP6V0A2,BCL2,PIKFYVE,LPCAT1,LRSAM1,ATP6V0D1,PHKG2,PABPC1,SOCS5,RB1CC1,PIP4K2C,GBA,PSMA1,USP10,ADRB2,PTTG1IP,PSMB3,DAPK3,PSMC4,TSC1,HSPBP1,CDC27,GOLGA2,NSF,EXOC4,FAM83D,CTSA,SNRNP70,RNF14,RNF139,TOB1,ZC3HAV1,CDKN2A,RNF114,EGLN1,ZNF207,FEZ2,ATXN3,SUMO2,RRAGC,BCL2L1,ATP6V1B2,PRKACA,ANKIB1,BCAP31,EPM2A,USP5,RAD23A,UBXN2A,ATP6V0B,MDM2,PSMA6,RALB,UCHL5,TBC1D14,PIN1,CDKN1B,PARL,ANAPC7,RNF19A,PDCL3,HTRA2,ATP6V1G1,UBQLN4,TIMP2,POLR2G,PSMA8,RAB7A,BTG2,CUL3,PSMB7,ATP6V0A1,CDC23,VDAC1,EDEM2,RAB1A,PSMB9,USP36,CHMP4A,CDC16,HNRNPR,VPS26B,TAB2,NSMCE2,PSMD3,ARNTL,CHMP4B,XRCC3,TRIM32,SCARB1,GEN1,SMURF1,SMAD4,CSNK1D,USP13,DAP,SECISBP2,CSNK1A1,PIP4K2A,MAD2L2,FBXO5,PPP1R3B,PSMD2,PTEN,STAT3,TPCN1,RNF5,TNFAIP3,KAT2A,ANAPC2,PDE3B,SH3GLB1,MAPK3,TFEB,MTMR3,GNA12,HGS,KEAP1,UPF1,ATP6V1D,OAZ2,PML,LRPPRC,PSAP,ATP6V1C1,PGAM1,UBE2C,CD81,TERF1,ESPL1,ANAPC4,IFI16,FAF1 |
| 7.166e-21 | -46.38 | SPIELMAN_LYMPHOBLAST_EUROPEAN_VS_ASIAN_UP | MSigDB lists | SPIELMAN_LYMPHOBLAST_EUROPEAN_VS_ASIAN_UP | 454 | 147 | 17377 | 2626 |
POLA2,FGFR1OP,ENSA,GLUD1,NENF,FKBP2,PARK7,BCAT2,CDK5,RAB8A,CDC42,DPYSL2,AP3S2,XRCC2,KIF22,TCEA1,TECR,TACC3,PGAP2,DEAF1,ERCC1,SNRNP200,ZBED5,EZR,ARHGDIB,NUTF2,ICMT,CCNF,LUC7L,RAB5B,RPL37,STT3A,TPP2,MAP4,NAGLU,PTPN7,PQBP1,CRCP,BAZ1B,VPS4A,DVL1,RTN3,OAZ1,HDAC2,B4GALT2,PPIB,COX5B,NDUFV2,NACA,CENPF,RRM1,B4GALT1,COX4I1,PMF1,MYL6B,SPAG5,RPN1,VASP,BANF1,MEA1,EI24,YBX1,AHCY,POLR2I,PRIM2,ZNF84,PRRC2A,NSDHL,LDB1,TOMM40,MAP2K2,SF3A2,PSMB3,RPL36,NAP1L1,GOLGA2,CSK,TCOF1,RBBP4,MYO9A,NUDT3,SART1,ATXN3,RPLP2,PTTG1,SMARCA4,AP1B1,PAIP1,HNRNPA2B1,TERF2IP,FARSA,MTA1,PIN1,GPX4,NARF,MEF2D,NDUFA7,NDUFB1,MBD3,H2AFV,GFER,FKBP3,ATP1A1,ACYP1,SAFB,PPA2,H2AFX,FAU,TUBB,SRGN,CDK2AP2,ARF1,SLC12A9,IL21R,NCAPG,WWP2,EBP,ERH,DNAJC8,NDUFA2,NDUFB4,ARF5,ZDHHC13,RPL19,NDUFS8,CNPY3,NDUFA3,PPAN,CSNK1G2,HMGN1,NET1,HEBP2,RPL27A,MACF1,HAGH,CDK11A,POLE,ZNF330,ACOX1,SNAP29,DBI,KHSRP,IMPDH1,PKD2,UBE2C,TAF6,IFI16 |
| 7.278e-21 | -46.37 | cellular component biogenesis | biological process | GO:0044085 | 2699 | 576 | 17256 | 2622 |
RAB14,FGFR1OP,ADD1,XIAP,CNTROB,MIS12,RPL23A,CDK5,NAPG,NEK6,DNAAF2,RAD23B,DNM2,NUP153,FTSJ3,ERCC1,RHOBTB3,AATF,MCM2,STOML2,AHNAK,MID1IP1,SMAD2,RPS27A,AXIN1,RNASEL,SMAD1,SLC25A33,NDUFV2,RHOC,DHX9,RAB23,KCTD17,HAUS4,ITGB5,PSMD9,HAUS2,CDC73,MCTS1,ATG4A,TFAP4,CD59,DDX56,PDXP,GEMIN4,NUP85,NSUN4,PPP6R1,LUC7L2,CYFIP1,TSPYL4,RB1CC1,TEX10,GTPBP4,RPS10,MYBL2,SRSF5,EIF4H,RHOB,WIPI2,NDE1,CFAP20,NUP58,ZNF207,RHOG,POC1A,CHD1L,ANK3,ACTR3,C5orf30,TPX2,EFL1,PRKACA,GLRX3,STAM,APP,CLUAP1,AHCTF1,SH3BP1,UTP18,NUP107,NSFL1C,SEPT11,CEP63,DCTN1,ULK3,GOPC,MAP4K4,CRNKL1,RPL38,POLR2D,CIRBP,ATP6V0A1,GORAB,NDUFA7,RAB1A,TAZ,MAT2A,DDX17,TAF2,KIF2A,LSM6,RPLP1,SNRPG,PPP5C,TUBB,RPS2,MZT1,ANXA6,SRSF6,FLOT1,ATG2B,WDR5,IFT27,RRP36,PNO1,KRI1,RPA2,PDCD10,NDUFB4,GEMIN6,NAP1L4,GTF2H2,PDPK1,TK1,TNFAIP3,TCTEX1D2,EMP3,RAB3IP,PICALM,RPA1,UTP20,PML,SSNA1,HMGB2,WDR45B,COX15,DDX47,MCCC1,EBNA1BP2,S1PR2,SEC16A,BIRC2,ATPAF1,PRNP,KRR1,DLG5,RAB8A,XRCC2,NOC2L,ZFYVE27,EIF5,PTPRK,PLK1,RPP25,EXOSC6,SEPT9,RBX1,BAZ2A,SNRPB,PSMG1,EZR,LNX2,UTP3,ANLN,LUC7L,LSG1,DPYSL3,EPB41,TRIM4,SEPT1,E2F4,ARRDC1,ACTB,DVL1,POT1,NAA60,GEMIN7,HJURP,CENPF,CTCF,RACGAP1,NCKAP1,ARID1B,RAPGEF6,VASP,CCP110,VMP1,MBD2,SSBP3,XPA,ARL6IP1,PREB,TRAPPC9,ACSL3,LDB1,UTP15,BBS12,RPL36,HAUS8,PCM1,SNAP23,TBPL1,PRMT7,RUVBL2,MYO9A,ECPAS,UNC13C,BCCIP,KCTD7,SART1,NDUFA5,CYLD,RPLP2,NDUFAF2,DYNLL1,XAB2,SLC2A1,RPL11,OIP5,MDM2,ABRAXAS2,PIN1,CORO1A,LMAN1,STRAP,DVL2,PRPF19,RPL29,RPL35,BIRC3,RAB7A,TUBGCP5,PRPF3,CHMP2B,TXNL4A,RPSA,SRSF1,IDE,UBXN2B,NDUFA11,XRCC3,CHMP4B,H3F3A,AP2S1,SMAD4,PARD3,RAD51D,NIFK,RRP15,CDT1,AGO2,ARFIP2,GTF3A,CSNK1A1,TUBGCP2,STARD9,NDUFV1,DDX31,CENPM,PTGES3,POLR1B,ORC3,CAMK2G,YTHDC1,PPAN,RHOA,SNX2,DDX23,SEC23IP,PDCD6,ATP6V1D,NEK1,BIRC5,SNAP29,PKD2,TAF12,CHMP7,UBE2C,PDCD6IP,MAX,NDUFB6,ZDHHC8,USP39,CUL1,OAT,CCNB1,UTP25,KIFC1,PA2G4,SNUPN,NOL11,AP2B1,TRA2B,TFG,SRSF10,USO1,ATG9A,NOL8,DDX20,AURKB,MCFD2,FOXRED1,MAK16,EIF3A,CLNS1A,WAS,BRD2,TMED10,PSMD8,LUC7L3,RPS14,EIF2D,ITGB1,PTPDC1,RRS1,RTN3,NMD3,MAPRE1,DHPS,PRKAA1,VAV2,DNAAF5,RRM1,B4GALT1,KIF23,PRPF39,PSEN1,VPS25,NDUFS7,NDUFS4,RTKN,CFLAR,FKBP1A,TMEM250,NDUFAF6,EXOSC7,HDAC7,ATP6V0A2,FBXL7,PIKFYVE,TNRC18,MRM3,TMED2,DDX28,SIGMAR1,WDR1,NOA1,SEPT8,RPS24,EXOSC9,ADRB2,CAPZA2,PLEC,CYFIP2,PKM,PATL1,CCT8,SF3A2,FAS,DERL1,SEC31A,CAT,EPRS,GOLGA2,NSF,RBMX,VCPIP1,CABIN1,PPP6R3,CDK2,CDKN2A,NDC1,REPS2,SF3B1,RAF1,URB2,EIF3D,RAC1,POMP,DECR1,GPX4,MRM2,CCT2,CDC123,CUL3,GAR1,TRIM28,CENPU,NSA2,RAD51C,HSPA4,CHMP4A,GOLGA8A,TBL3,H2AFX,BEND3,PDCD11,DYNC1LI2,ATMIN,CSNK1D,POLQ,PKP4,NDUFS1,TWNK,MECP2,BLM,RAB11A,PIP5K1C,NDUFA2,PTEN,RPL17,CENPJ,AXIN2,RPL19,NDUFA3,IFT46,PACS2,NEK7,TMEM126B,WDR18,RPL8,ADSL,BMS1,RPL27A,KIF11,TSR2,SH3GLB1,FADD,HGS,RPL32,CCDC69,NAXE,NDUFS5,WDR62,TAF6,DDB1,IPO4,BYSL,DDX52,NPHP4,ST13,NOP2,UBN1,UQCR10,AGFG1,TAF6L,SNRPD3,BRIX1,BECN1,MAP1LC3B,CUTC,EDC3,RAP1A,CDC42,EIF4A3,RAB35,ATG3,ZNHIT6,KHDC4,RPF2,NDUFB9,NFU1,CARMIL1,SRPK2,COPS8,SNRNP200,NCK1,FOPNL,TMEM216,RIOX2,ASF1B,CHAF1A,UBTF,GEMIN5,PAF1,RPL37,HSPB11,NIP7,MIA2,ATXN2L,CAB39,STK11,CHEK2,ROCK1,VPS4A,CLU,SASS6,RPS26,RPS15,TM9SF4,GORASP1,RPL15,MEF2A,PRPF18,NUP205,LYAR,CAPZA1,KIFAP3,BCL2,KNTC1,ATP6V0D1,HP1BP3,ATP5IF1,RPL6,EIF2A,SEPT7,CAND1,TSC1,NAP1L1,ODF2,NUP62,YWHAZ,RBBP4,EHD4,PDSS2,WASF2,PRKAB1,CHMP2A,CORO7,TOMM20,FAM92A,PLAGL2,SMARCA4,ANKRD28,FARSA,UBXN2A,RRN3,SAR1A,NVL,EXOSC1,PPP6C,CLTB,UTP4,HTRA2,CHP1,DMAC2,WIPF1,NDUFB1,PEF1,RPS9,ANP32E,SMURF1,ABCA1,TMEM33,MIF,KIF3B,SHPRH,DCTN2,NUP54,TIMM21,PAWR,FBXO5,FERMT3,FASTKD3,SEC24C,ANP32A,H2AFY,NDUFS8,ATG13,FBL,MRPL11,TTC17,TGFB1,PPP1R9B,COA3,NASP,TIMMDC1,ASPM,MEN1,MFN2,MAPK3,ACAT1,CENPT,PLOD3,TERF1 |
| 8.227e-21 | -46.25 | GO_MACROMOLECULAR_COMPLEX_ASSEMBLY | MSigDB lists | GO_MACROMOLECULAR_COMPLEX_ASSEMBLY | 1317 | 323 | 17377 | 2626 |
MAX,NDUFB6,XIAP,USP39,OAT,CCNB1,MIS12,RPL23A,KIFC1,NAPG,SNUPN,NEK6,DNAAF2,RAD23B,AP2B1,NUP153,TFG,SRSF10,USO1,DDX20,AURKB,MCFD2,MCM2,FOXRED1,CLNS1A,EIF3A,STOML2,AHNAK,WAS,MID1IP1,SMAD2,BRD2,TMED10,RPS27A,PSMD8,RPS14,LUC7L3,AXIN1,EIF2D,OGT,SMAD1,SLC25A33,NDUFV2,DHPS,PRKAA1,KCTD17,RRM1,KIF23,HAUS4,PRPF39,PSMD9,HAUS2,CDC73,NDUFS7,NDUFS4,MCTS1,TFAP4,CD59,FKBP1A,ATP6V0A2,GEMIN4,TNRC18,PPP6R1,NSUN4,LUC7L2,TMED2,EIF3L,DDX28,TSPYL4,RPS10,MYBL2,SRSF5,ADRB2,CAPZA2,EIF4H,PATL1,SF3A2,CCT8,FAS,DERL1,CAT,SEC31A,EPRS,GOLGA2,NSF,RBMX,CABIN1,PPP6R3,NDE1,CDKN2A,ZNF207,REPS2,SF3B1,RAF1,EIF3D,CHD1L,RAC1,TPX2,POMP,DECR1,AHCTF1,NUP107,TNPO2,SEPT11,CEP63,CCT2,CDC123,GOPC,RPL38,CIRBP,CRNKL1,CUL3,POLR2D,ATP6V0A1,NDUFA7,RAB1A,TAZ,TRIM28,TAF2,KIF2A,EIF3K,RAD51C,HSPA4,CHMP4A,PEX5,H2AFX,SNRPG,PPP5C,CSNK1D,TUBB,POLQ,NDUFS1,ANXA6,SRSF6,FLOT1,BLM,RAB11A,RPA2,NDUFA2,NDUFB4,CENPJ,AXIN2,GEMIN6,ANXA5,NAP1L4,NDUFA3,GTF2H2,TK1,TNFAIP3,NEK7,TMEM126B,ADSL,BMS1,KIF11,PICALM,SH3GLB1,FADD,RPA1,KEAP1,PML,HMGB2,NDUFS5,IPO4,DDB1,COX15,ST13,UBN1,UQCR10,SIRT2,SNRPD3,BRIX1,SEC16A,CUTC,BIRC2,ATPAF1,EDC3,PRNP,DLG5,ZNHIT6,XRCC2,NOC2L,RPF2,NDUFB9,SRPK2,SNRNP200,SEPT9,RBX1,NCK1,SNRPB,LNX2,RRM2,PSMG1,ANLN,LUC7L,ASF1B,CHAF1A,DPYSL3,GEMIN5,PAF1,TRIM4,NIP7,ATXN2L,CAB39,STK11,CLU,CHEK2,NAA60,GEMIN7,RPS15,HJURP,GORASP1,CENPF,CTCF,RACGAP1,PRPF18,NUP205,VASP,SSBP3,MBD2,XPA,CAPZA1,KIFAP3,KNTC1,ALDH18A1,PREB,HP1BP3,TRAPPC9,ACSL3,RPL6,EIF2A,SEPT7,BBS12,CAND1,HAUS8,TSC1,NAP1L1,SNAP23,PRMT7,NUP62,RBBP4,EHD4,PDSS2,KCTD7,NDUFA5,PRKAB1,SART1,CHMP2A,CYLD,TOMM20,CORO7,NDUFAF2,XAB2,SLC2A1,PLAGL2,SMARCA4,RPL11,ANKRD28,OIP5,MDM2,PPP6C,LMAN1,STRAP,DVL2,PRPF19,BIRC3,TUBGCP5,WIPF1,PRPF3,NDUFB1,TXNL4A,EIF3G,RPSA,EIF3H,SRSF1,IDE,NDUFA11,XRCC3,CHMP4B,H3F3A,AP2S1,ABCA1,SMAD4,PARD3,RAD51D,TMEM33,MIF,KIF3B,CDC40,SHPRH,NUP54,ARF1,CSNK1A1,TUBGCP2,FERMT3,FBXO5,STARD9,NDUFV1,SEC24C,H2AFY,NDUFS8,CENPM,TTC17,MRPL11,CAMK2G,PPAN,YTHDC1,TGFB1,RHOA,NASP,SNX2,TIMMDC1,ASPM,MEN1,MAPK3,DDX23,SEC23IP,BIRC5,SNAP29,ACAT1,CENPT,UBE2C,TERF1,HRAS |
| 9.280e-21 | -46.13 | G3BP1 (G3BP stress granule assembly factor 1) | protein interactions | 10146 | 423 | 146 | 17029 | 2761 |
DDX47,PDCD6IP,NUP188,TXN,HNRNPAB,LUZP1,YTHDF3,CUL1,SND1,PABPC4,DST,PA2G4,PCNA,DPYSL2,SRSF4,SRI,PDS5B,TCEA1,FTSJ3,CDC5L,NSUN2,MKI67,PRKRA,MCM2,CBFB,LUC7L,CLNS1A,EIF3A,DPYSL3,MAP4,ITGB1,ATXN2L,BCL7C,COX5A,KPNA2,MAPRE1,PRKAA1,CENPF,TIA1,KIF23,RACGAP1,SRRT,CDC73,NUP205,LMNA,VASP,EIF2S2,MCM5,BANF1,RTCB,YBX1,ALDH18A1,PABPC1,EIF3L,PRRC2A,SUGP2,USP10,EIF2A,CAPZA2,FXR1,EIF4H,EIF4G2,ISG15,CAND1,MAGED2,KPNA1,SYNCRIP,PDLIM1,CSK,NUP62,ATP5F1A,RBBP4,PDLIM5,ZC3HAV1,CYLD,MAGED1,EIF3D,SAFB2,APP,GNB2,USP5,CSDE1,UTP18,PIN1,PPME1,TNPO2,TARDBP,RBM12B,STRAP,CFL1,CSTF1,PPP1R18,RPL35,RFC3,MAP4K4,SMU1,CUL3,DNAJA1,RAB1A,H2AFV,EIF3G,EIF3H,EIF3K,CHCHD3,HSPA4,STAT1,RBMS1,ANP32E,FAU,ANXA6,AGO2,PAWR,WWP2,KRI1,PTPN2,PSMD2,ADD3,DNAJC8,CLIC4,CTNNBL1,SEC24C,PELO,PTGES3,FBL,MSH6,SMC4,LDHB,NUDC,PDPK1,CSNK1G2,STAU1,HMGN1,TUFM,ADSL,MACF1,CIP2A,PRDX1,UPF1,ATAD2,PFDN4,MFAP1,ZC3H7B,SRSF3,YWHAH,PURA,FAF1 |
| 1.418e-20 | -45.70 | GO_DNA_METABOLIC_PROCESS | MSigDB lists | GO_DNA_METABOLIC_PROCESS | 692 | 198 | 17377 | 2626 |
POLA2,PTMS,THOC1,UBE2I,FANCI,MBD4,LIN9,TET3,FANCL,PCNA,XRCC2,RAD23B,CRY2,KIF22,TCEA1,MCMBP,DNMT1,OGG1,CDC5L,COPS8,TDP1,ERCC1,EXOSC6,BAZ2A,RBX1,RAD51AP1,NOL8,EHMT1,MKI67,RRM2,UBE2V1,CDC6,BRCA1,MCM2,RFC2,GINS4,CHAF1A,PRIM1,RAD18,TONSL,RPS27A,MYO18A,BAZ1B,KPNA2,CHEK2,COPS6,POT1,SLC25A33,SSRP1,UBE2D3,RECQL,NSMCE4A,CLSPN,POLR2K,CHTF18,MUM1,CENPF,CIB1,RRM1,CTCF,TOP2B,RLF,JMY,WDR48,NPLOC4,DTL,SMC3,MCM5,BANF1,XPA,MSH2,TIMELESS,TERF2,POLR2I,PRIM2,MTA2,USP10,MPG,ISG15,XRCC5,GNAS,NAP1L1,KPNA1,PALB2,POLR2J,CDCA5,PRMT7,DTD1,RUVBL2,YY1,ZNF830,RBBP4,CDK2,USP7,BCCIP,ATXN3,DNMT3A,FOXM1,XAB2,SUMO2,CHD1L,PTTG1,PMS2,RMI2,INO80E,ORC1,RPAIN,RAD23A,TERF2IP,SP100,KDM2A,UCHL5,DUT,MTA1,RNASEH2A,AQR,TOP1MT,PRPF19,MND1,RFC3,POLR2L,POLR2G,BTG2,KAT7,PPIE,TAOK1,POLR2D,SLBP,DCLRE1C,KDM1B,FANCE,GAR1,POLG2,TRIM28,RAD54B,SUPT16H,RAD51C,NSMCE2,UHRF2,H2AFX,RBMS1,XRCC3,BEND3,PPP5C,GEN1,XRCC4,EYA2,CSNK1D,RAD51D,POLQ,SLC30A9,DNAJC2,MCM10,TRIP12,SHPRH,EYA1,TCF3,CDT1,BABAM1,DBF4,SMC6,BLM,RMI1,MAD2L2,NEIL2,WRNIP1,RFWD3,RPA2,HUWE1,AXIN2,COPS7B,PTGES3,ORC3,GTF2H2,MSH6,GINS1,HMGN1,TK1,HEMK1,NASP,POLK,HELB,PRKDC,PARP4,TOP3A,MEN1,POLR2A,RPA1,UPF1,POLE,TATDN2,NEIL3,HMGB2,RBPJ,TATDN1,TERF1,PURA,DDB1 |
| 1.521e-20 | -45.63 | PENG_GLUTAMINE_DEPRIVATION_DN | MSigDB lists | PENG_GLUTAMINE_DEPRIVATION_DN | 320 | 115 | 17377 | 2626 |
SRM,ZNF207,RHOG,KARS,HNRNPAB,TAP1,TMEM109,UCK2,EBNA1BP2,SLC29A1,FKBP2,CCNB1,PCBP1,BCAP31,HNRNPA2B1,FARSA,PSMD1,PSMA6,ATP2A2,SAR1A,EIF4A3,UTP18,PIK3R2,POP7,RAD23B,TARDBP,APOOL,EIF5,PDIA6,STRAP,DCTN1,PRPF19,METTL1,PPIF,CCT2,SEC61B,MAPRE2,CELSR2,CDC123,ERF,IDH3A,MRPL12,DNAJA1,VDAC1,OGFR,TXNL4A,ODC1,TRIM28,DHX15,SRSF1,ALG3,HSPA4,TMED10,PSMD8,TIMM17A,TBL3,PSMD3,U2SURP,STAT1,KPNA2,PRPF4,RRS1,RPS26,MYL12B,PFKP,TUBB,PPIB,EWSR1,DHX9,CYCS,DNAJB1,SRRT,TFRC,NUP205,EBP,ERH,EXOSC7,AHSA1,FAM89B,FBL,LPCAT1,UBE2M,MED22,NUDC,FDFT1,LDHB,TGFB1,AMD1,LDHA,EMP3,RANGAP1,BMS1,TOMM40,EIF4G2,ABCF1,PSMB3,PRDX1,XRCC5,CBX3,YIF1A,SLC19A1,SYNCRIP,CCDC6,ACLY,IMPDH1,KHSRP,RUVBL2,SNRNP70,PGAM1,PTDSS1,HRAS,MRPL3,ZC3HAV1,GCSH,BYSL |
| 1.657e-20 | -45.55 | GO_RIBONUCLEOPROTEIN_COMPLEX_BIOGENESIS | MSigDB lists | GO_RIBONUCLEOPROTEIN_COMPLEX_BIOGENESIS | 405 | 135 | 17377 | 2626 |
DDX47,NOP2,USP39,EBNA1BP2,SNRPD3,BRIX1,EDC3,KRR1,RPL23A,PA2G4,SNUPN,NOL11,EIF4A3,ZNHIT6,NOC2L,RPF2,FTSJ3,SRPK2,SRSF10,RPP25,EXOSC6,SNRNP200,AATF,SNRPB,NOL8,DDX20,UTP3,LUC7L,MAK16,LSG1,EIF3A,CLNS1A,GEMIN5,RPL37,NIP7,RPS27A,RPS14,LUC7L3,EIF2D,ATXN2L,RNASEL,RRS1,RPS26,NMD3,GEMIN7,RPS15,RPL15,PRPF39,PRPF18,MCTS1,DDX56,EXOSC7,GEMIN4,NSUN4,LUC7L2,DDX28,EIF3L,NOA1,TEX10,UTP15,RPS10,GTPBP4,RPL6,RPS24,EXOSC9,SRSF5,EIF2A,EIF4H,SF3A2,PATL1,ABCF1,RPL36,TSC1,PRMT7,CDKN2A,SART1,RPLP2,XAB2,SF3B1,EIF3D,RPL11,RRN3,NVL,UTP18,EXOSC1,STRAP,PRPF19,RPL29,RPL35,CDC123,POLR2D,CIRBP,CRNKL1,RPL38,PRPF3,TXNL4A,GAR1,EIF3G,RPS9,EIF3H,RPSA,SRSF1,EIF3K,NSA2,LSM6,TBL3,RPLP1,SNRPG,FAU,PDCD11,CSNK1D,RPS2,CDC40,SRSF6,RRP36,PNO1,RPL17,GEMIN6,RPL19,DDX31,MRPL11,FBL,ERI3,PPAN,YTHDC1,WDR18,RPL8,BMS1,RPL27A,TSR2,DDX23,UTP20,RPL32,BYSL,DDX52 |
| 1.867e-20 | -45.43 | MORF_DAP3 | MSigDB lists | MORF_DAP3 | 184 | 80 | 17377 | 2626 |
KARS,NUP188,HNRNPAB,DYNLL1,SUMO2,STARD7,UBE2I,SDHA,PARK7,HNRNPA2B1,PIN1,CS,HADHB,RPN2,TCEA1,AHCYL1,SP3,CCT2,SNRNP200,SEC61B,AATF,SNRPB,VDAC2,PSMB7,TMEM147,SLC25A5,SERP1,CLNS1A,RHEB,STOML2,ALG3,EIF3K,DAP3,DDOST,PSMD8,TBL3,UQCRH,COPS6,SMNDC1,ZNF146,SLC30A9,COX5B,MRPL9,PHB2,PDAP1,COX4I1,XPO7,EBP,PSMD2,NDUFV1,DNAJC8,HUWE1,ARPC5,BANF1,CAPZA1,NAP1L4,CYC1,NIPSNAP1,POLR2I,JTB,TUFM,SSR2,DDX39A,SNRPA,PSMB3,CBX3,XRCC5,EPRS,SETD3,COX7A2L,ACLY,LRPPRC,COX8A,IMPDH1,PPP1R11,YWHAZ,MDH1,RUVBL2,IDH3B,DDB1 |
| 2.280e-20 | -45.23 | STARK_PREFRONTAL_CORTEX_22Q11_DELETION_DN | MSigDB lists | STARK_PREFRONTAL_CORTEX_22Q11_DELETION_DN | 459 | 147 | 17377 | 2626 |
TXN,H2AFZ,ST13,UQCR10,ZDHHC8,USP39,NENF,SIRT2,FKBP2,OAT,CDK5,TIMM23,POP7,RAD23B,AKR1B1,TRA2B,NFU1,CARM1,ELOF1,USP34,MBLAC2,WDR82,KRTCAP2,SLC25A5,GINS4,RHEB,CLNS1A,BRWD1,BAZ1B,KPNA2,VPS4A,COPS6,PSMC1,SEPHS2,COX5B,NDUFV2,UFC1,NACA,C19orf25,RPL15,CYCS,FAM136A,TMEM165,PDXDC1,NDUFS7,NDUFS4,DDRGK1,MCTS1,DDX56,C4orf3,BUD31,MEA1,SLC27A4,CYC1,MRPL40,NIPSNAP1,TIMM8B,EIF3L,TSPAN31,RIT1,EIF4G2,PSMB3,NMT2,ARHGAP15,PSMC4,PFDN5,HSPBP1,FNTA,KPNA1,PCM1,GOLGA2,POLR2J,PRPS2,DCAF11,GPI,MZT2B,MRPL3,NIPA1,ZNF511,BCCIP,CORO7,UGP2,MDH2,ANK3,POMP,HCFC1R1,BCAP31,COMMD8,RAD23A,PHC2,NUDT19,CYHR1,STRBP,BCAP29,SPSB3,CCT2,SEC61B,PPT1,IDH3A,SMU1,VDAC2,ABHD11,TMEM147,NDUFA7,FKBP3,EIF3H,CCDC127,EIF3K,DAP3,MRPL55,CHCHD1,TIMM17A,NDUFA11,HAGHL,CHMP4B,B4GALT3,SLC25A39,NDUFS1,MRPL42,GTF3A,SAC3D1,COQ4,NDUFA2,AHSA1,NDUFS8,MRPL11,ERI3,RPL22L1,S100A6,SLC25A1,NUDC,STAU1,GUK1,RPL8,HAGH,TTC33,PRDX1,CBX3,ATP6V1D,PDCD6,ELMO1,PRDX3,GLG1,ASNA1,PURA,HIGD2A,GCSH |
| 2.468e-20 | -45.15 | BLUM_RESPONSE_TO_SALIRASIB_DN | MSigDB lists | BLUM_RESPONSE_TO_SALIRASIB_DN | 330 | 117 | 17377 | 2626 |
POLA2,H2AFZ,PTTG1,TPX2,ZNF107,KIF2C,ORC1,STMN1,HNRNPA2B1,CDKN2C,PCNA,CCNA2,DUT,ADCY9,RAB4A,NUP107,PDCD2,TRA2B,KIF22,CDC25B,RNASEH2A,TECR,F2R,SMARCE1,DNMT1,TACC3,SRSF10,PLK1,MAPRE2,RFC3,SEPT9,RBX1,RAD51AP1,PBK,MKI67,KIF15,NARF,PFKFB3,RRM2,NUSAP1,CDC6,AURKB,BRCA1,SMC2,SOX4,CCNF,MCM2,CBFB,RFC2,H2AFV,FKBP3,DHX15,CHAF1A,SRSF1,PRIM1,DPYSL3,HNRNPR,KPNA2,TUBB,USP13,EWSR1,B4GALT5,SRSF6,ANKH,CENPF,RRM1,DHX9,TIA1,KIF23,TOP2B,PXMP2,RGS2,NCAPG,SRRT,SPAG5,LMNA,EBP,FBXO5,TNS3,NDUFA2,MCM5,MSH2,PRC1,TIMELESS,H2AFY,ANP32A,MSH6,HNRNPM,SMC4,TK1,NASP,PRKDC,MYBL2,LDHA,DDX39A,KIF11,CYB5A,RPA1,CBX3,DDX23,GALNT2,SYNCRIP,POLE,TWSG1,PRDX3,DCK,TFE3,OAZ2,TFDP1,ACLY,E2F1,SRSF3,CDK2,CCNB2,PGAM1,UBE2C,ESPL1 |
| 2.937e-20 | -44.97 | PUJANA_XPRSS_INT_NETWORK | MSigDB lists | PUJANA_XPRSS_INT_NETWORK | 160 | 73 | 17377 | 2626 |
FOXM1,SUZ12,CSNK2A1,STMN1,FANCI,KIFC1,CDKN2C,PCNA,CCNA2,DUT,DNMT1,SRSF10,RFC3,AATF,HMGN4,NCK1,RAD51AP1,SNRPB,MKI67,DNAJC9,AURKB,BRCA1,SMC2,MCM2,CCNF,H2AFV,EIF3H,MAT2A,CHAF1A,RAD51C,ACYP1,PRPF4,ANP32E,CHEK2,TFDP2,FUBP1,RECQL,TCF3,RRM1,CTCF,BLM,CNOT3,RB1,SMC3,MCM5,MSH2,GTSE1,TIMELESS,KNTC1,CPSF4,SMC4,GINS1,SRSF11,HMGN1,NASP,PRKDC,ILF3,MYBL2,NFATC2IP,DDX39A,SNRPA,CBX3,RPA1,SEC31A,POLE,ZNF330,TFDP1,HMGB2,SRSF3,IDH3B,RBBP4,UBE2C,ESPL1 |
| 3.094e-20 | -44.92 | MORF_MAP2K2 | MSigDB lists | MORF_MAP2K2 | 126 | 63 | 17377 | 2626 |
COX5B,KARS,MRPL9,H2AFZ,NUP188,HNRNPAB,RAC1,COPE,DCTN2,STARD7,SLC4A2,CYCS,XPO7,AP3S1,GNB2,SDHA,PARK7,BCAP31,RAD23A,SF3B2,RPN1,NDUFV1,MTA1,BANF1,CAPZA1,CS,HADHB,TCEA1,CYC1,GPX4,IFRD1,SNRNP200,POLR2I,PPT1,NSDHL,PSMB7,JTB,TUFM,VDAC2,RANGAP1,TMEM147,MAP2K2,TRIM28,SNRPA,RHEB,SDHB,EIF3K,DDOST,PRDX3,TBL3,PSMD8,PPM1G,COX8A,IMPDH1,MDH1,RUVBL2,GPI,NDUFS5,IDH3B,PTDSS1,AP2S1,SSSCA1,HDAC2 |
| 3.419e-20 | -44.82 | WONG_EMBRYONIC_STEM_CELL_CORE | MSigDB lists | WONG_EMBRYONIC_STEM_CELL_CORE | 327 | 116 | 17377 | 2626 |
CCNC,HNRNPAB,NOP2,GNPDA1,MRPL39,SLC2A1,EBNA1BP2,ORC1,BRIX1,TCF19,POLR3K,FARSA,PA2G4,PCNA,CCNA2,IARS,UTP18,POP7,RAD23B,NUP107,PDCD2,KIF22,DNMT1,SRSF10,PLK1,RFC3,MRPL12,E2F3,RNPS1,NLN,RRM2,WDHD1,NUSAP1,CDC6,GLO1,AURKB,SMC2,CCNF,MCM2,SLC25A5,RPSA,EIF3A,CHAF1A,STOML2,PRIM1,EIF3K,DAP3,TIMM13,MID1IP1,RAD18,NIP7,PPM1G,NDUFA11,UQCRH,KPNA2,ANP32E,CHEK2,BTF3,MRPL13,SEPHS2,COX5B,MRPS2,GSPT2,DBF4,CDCA8,RRM1,CDCA3,DHX9,KIF23,RACGAP1,CYCS,FAM136A,BLM,SPAG5,DTL,RPA2,EXOSC7,EIF2S2,GART,MCM5,BANF1,MSH2,GTSE1,GEMIN6,ACAD8,FBL,MRPL11,PABPC1,SMC4,NIPSNAP1,TIMM8B,EIF3L,NASP,HMGN5,PRIM2,MYBL2,ADSL,KRAS,MRPL16,RPL27A,KIF11,SNRPA,PRDX1,XRCC5,CBX3,NAP1L1,MTHFD2,BIRC5,CDCA5,SLC16A1,HMGB2,RUVBL2,TCOF1,YY1,CCNB2,TERF1 |
| 3.650e-20 | -44.76 | HALLMARK_G2M_CHECKPOINT | MSigDB lists | HALLMARK_G2M_CHECKPOINT | 193 | 82 | 17377 | 2626 |
POLA2,H2AFZ,PTTG1,UCK2,TPX2,CUL1,KIF2C,MAPK14,STMN1,CDKN2C,CCNA2,RAD23B,PDS5B,CDKN1B,TNPO2,TRA2B,KIF22,CDC25B,ARID4A,TACC3,SAP30,SRSF10,PLK1,PBK,CUL3,MKI67,KIF15,E2F3,NUSAP1,CDC6,AURKB,SMC2,CCNF,MCM2,H2AFV,ODC1,CHAF1A,SRSF1,RBL1,E2F4,H2AFX,KPNA2,E2F2,POLQ,PRPF4B,EWSR1,CENPF,DBF4,CTCF,KIF23,RACGAP1,NOTCH2,FBXO5,RPA2,KIF5B,MCM5,PRC1,SLC12A2,SMC4,YTHDC1,TGFB1,NASP,PRIM2,AMD1,ILF3,MYBL2,KIF11,DDX39A,HMGN2,UPF1,POLE,SYNCRIP,CDC27,BIRC5,ODF2,TFDP1,E2F1,PML,CCNB2,UBE2C,PURA,ESPL1 |
| 3.660e-20 | -44.75 | MORF_PRKDC | MSigDB lists | MORF_PRKDC | 182 | 79 | 17377 | 2626 |
IMMT,NUP188,STARD7,PABPC4,RAD23A,HNRNPA2B1,CDKN2C,IARS,GOT2,PIN1,DUT,TXLNA,MRPS27,CS,TCEA1,DNMT1,DEAF1,SNRNP200,AATF,HMGN4,IDH3A,PPIE,VDAC2,SLBP,PKMYT1,MCFD2,MCM2,TXNL4A,CHAF1A,ALG3,CDC16,HNRNPR,TIMM17A,SAFB,PSMD3,BAZ1B,SCARB1,HDAC2,SSRP1,RRM1,LANCL1,XPO7,TFAP4,RPA2,PSMD2,RPN1,DNAJC8,EIF2S2,MCM5,EI24,CAPZA1,TNPO3,ANP32A,NUDC,MLEC,PRKDC,WDR18,PSMA1,DCTD,BMS1,SEPT7,DDX39A,CDK11A,ABCF1,SNRPA,TARS,POLR2A,XRCC5,EPRS,TFDP1,PRPS2,LRPPRC,KHSRP,NUP62,TCOF1,RUVBL2,CDK2,PTDSS1,DDB1 |
| 3.720e-20 | -44.74 | RODRIGUES_THYROID_CARCINOMA_ANAPLASTIC_UP | MSigDB lists | RODRIGUES_THYROID_CARCINOMA_ANAPLASTIC_UP | 664 | 191 | 17377 | 2626 |
SKA3,COPA,ADAM10,CCNB1,BRIX1,MAPK14,PAPOLA,LIN9,ATP13A3,RPF2,MOB1A,EIF5,MYBL1,DNMT1,FGFR1OP2,CDC5L,USP34,FYTTD1,LARS,USO1,RHOBTB3,NRAS,MIOS,DPM1,RAD51AP1,SNRPB,NOL8,TLK1,LACTB,GMFB,WDHD1,AURKB,SMC2,ANLN,MCM2,STX16,CBFB,STK17B,ANKRD10,AHNAK,BRWD1,PDRG1,RPS27A,ZNF367,U2SURP,ITGB1,KPNA2,MRPL13,NMD3,DDX58,RECQL,TM9SF4,PRKAA1,TRIO,CENPF,DHX9,TIA1,RACGAP1,RLF,LYAR,SMC3,EIF2S2,MED8,KLHL5,VMP1,RBM34,UBE3C,CSNK1G3,SRSF11,EIF5A,IFRD1,PRIM2,ERLIN1,OXR1,CAMSAP1,GTPBP4,UTP15,USP10,BCLAF1,PLEC,FXR1,EIF4G2,MATR3,TWISTNB,FAS,EPRS,SLCO4A1,MTHFD2,CEBPG,SLC16A1,YWHAZ,CTSA,CDKN2A,ATXN3,TP53RK,FOXM1,SF3B1,CAST,SLC2A1,UCK2,TPX2,NUF2,BCL2L1,GLRX3,SP100,IARS,KIF14,NUP107,TAP2,TTC3,CEP63,LMAN1,MOSPD1,CCT2,BIRC3,GOPC,NLN,TOR1AIP2,NUSAP1,SUPT16H,KIF2A,DNAJC10,ZNF317,HSPA4,ZNF700,CORO1C,STK38,CEP55,SEL1L,RBMS1,MAPK1,XRCC4,ZBTB11,SMURF1,ZNF146,CSNK1D,PRPF4B,CDC40,DEPDC1,MRPL42,RAE1,SRSF6,B4GALT5,SRGN,TRMT6,DBF4,BRAP,SMC6,SIKE1,CHAC2,CSNK1A1,GFM2,SCYL2,TFRC,ZNF92,KIF5B,GART,CLIC4,SLC1A4,TANK,NAA50,PTPN11,GTF2H2,MSH6,SMC4,RPAP3,MOB4,TGFB1,TTPAL,ASPM,BTAF1,METTL5,PPWD1,BORA,DDX39A,KIF11,API5,TARS,CBX3,KPNA4,KIF18A,ATAD2,PFDN4,OSBPL8,IMPDH1,FAM126A,UBE2C,FAF1,IFI16,ESYT2,DDX52 |
| 4.118e-20 | -44.64 | lung-carcinoma-non_small_cell_carcinoma | COSMIC cancer mutations | lung-carcinoma-non_small_cell_carcinoma | 5292 | 988 | 17385 | 2587 |
RAB14,FGFR1OP,KDM4A,ABCC10,PIGQ,XIAP,DHX8,LACTB2,PPP1R16B,RBM4,ZNF275,FBXO22,EEF2K,CDKN2C,CDK5,NEK6,RABGAP1L,RAD23B,SRSF4,UPRT,NUP153,RNF26,SENP1,PCBP2,MLST8,PLK3,BAK1,ZNF672,CCDC57,ERCC1,ZNF559,RHOBTB3,NRAS,GABPA,MCL1,TOPORS,PLEKHM3,SMC2,PPFIA3,MCM2,ICMT,RAB22A,ARF4,KRIT1,TRIM47,SMAD2,MID1IP1,WDR11,RAD18,PDRG1,LIMK1,AXIN1,OGT,RNASEL,FBXL3,TFDP2,SMAD1,E2F2,PDCD4,PFKP,NXT2,SSRP1,DDX42,CLSPN,KIAA0100,PHF23,RHOC,TRIO,RAB23,CERK,TOP2B,EZH1,EIF2AK4,PDCD7,ITGB5,APH1B,HAUS2,LMNA,MCTS1,ATG4A,DDX56,SLC38A5,RNFT1,INTS7,INPP5A,MCM5,FBXO7,PHF14,ZNF326,FOXN2,GEMIN4,NUP85,PHKG2,SRSF11,IFRD1,ETV3,FOXK1,PRRC2A,DHX29,MTA2,GTPBP4,MYBL2,ITM2A,USP10,BCLAF1,SRSF5,MTX1,MPG,ELK1,EIF4H,ABCF1,RHOB,PTPRF,MAGED2,DTWD1,KPNA1,ETS2,DUSP3,MDH1,SNX14,RNF139,ALS2,EGLN1,RHOG,TRIM41,TRERF1,PTTG1,CHD1L,TPX2,MYH9,NUF2,PRKACA,SAFB2,KTN1,RAB21,PRKD3,FBXL6,ZNF420,SH3BP1,DUT,MTA1,UBA5,DDA1,ZCCHC2,NUP107,SEPT11,ANAPC7,RNF19A,MAVS,RBM15,ARL5A,SNX8,GOPC,IDH3A,MAP4K4,CIRBP,E2F3,MEF2D,DNAJA1,RAB1A,TAZ,FKBP3,DDX17,KIF2A,TAF2,PPP2CA,CDC16,LSM6,CORO1C,HIPK2,WDR7,RNF38,DMWD,FUS,PDXK,PPP5C,GEN1,USP13,ANXA6,SRSF6,SESTD1,CCM2,TRAK1,SIKE1,ABHD14B,UBE4A,IP6K2,IL21R,ETS1,IFT27,SLC25A43,NEIL2,PPP1R3B,FBXO3,RPA2,ERH,PDCD10,CLIC4,ITGB8,SUV39H2,GATC,HUWE1,PPP1R8,ARF5,ARHGEF1,GEMIN6,UBE3B,FBXL19,GTF2H2,TPCN1,S100A6,IMPA2,LDHB,PDPK1,STAU1,PPP3CA,TK1,TNFAIP3,DDX24,POLK,LDHA,MTMR12,RAB3IP,DDX39A,PICALM,RPA1,SH3BP5,KEAP1,MAGT1,POLE,CCDC6,WNT5B,PITX1,MAPK6,FAM3C,PML,AEN,HMGB2,RGL1,WDR76,CD81,YWHAH,IGBP1,FAF1,ANAPC4,TMEM131,COX15,DDX47,THOC1,WDR13,TRIM11,PPP1R15B,SNX15,CSNK2A1,GIT2,BIRC2,FANCI,PRNP,FANCL,ABL2,RAB8A,PCNA,NUP210,NT5DC1,IL6ST,PIK3R2,XRCC2,ETV6,MYBL1,MCMBP,ASB6,PTPRK,VPS13B,PLK1,SP3,PTPN18,CELSR2,SEPT9,MIOS,RBX1,PBXIP1,SNRPB,RAD51AP1,TLK1,GMFB,LNX2,EZR,CDC6,LRP5,UBE2V1,UTP3,PBRM1,BRCA1,ANLN,RAB5B,USP21,RHEB,TRIM4,SEPT1,FBXO28,CHD3,E2F4,SOCS4,BCL7C,ADAM9,KPNA2,ACTB,PIEZO1,DVL1,NUDT11,POT1,NUMB,FUBP1,HJURP,PHB2,DNAJB2,NKD2,LAMTOR3,KLC1,RACGAP1,COX4I1,ADCK5,CDK13,RAB6A,DNAJB1,PPP3CB,RSAD1,RAPGEF6,RB1,NUS1,VMP1,MBD2,XPA,SLC27A4,RBM3,AFF1,MAML1,CYTH1,ABHD2,TRAPPC9,NSDHL,ACSL3,LDB1,CAMSAP1,UTP15,KRAS,EIF2AK1,MAP4K3,UBE4B,ICAM2,ARPC1A,EIF4G2,IRF5,SDHB,MBIP,PCM1,CDC27,SYNCRIP,PALB2,COX7A2L,PRPS2,ZDHHC7,RUVBL2,BTBD10,CCNB2,BCCIP,USP7,SART1,TRAF7,SUCLG1,ARID2,FOXM1,XAB2,SUMO2,LAGE3,PCBP1,LYN,DUSP22,BCAP31,RAD23A,RPL11,VAV1,MRPL50,CSDE1,PDK2,PSMA6,MDM2,WDR44,PIN1,PDCD2,CORO1A,MINPP1,AHCYL1,STRAP,SAP30L,SPSB3,DVL2,SNX25,KDM3B,ARHGAP17,MND1,BIRC3,BTG2,RAB7A,DNAJC9,NUP155,DCLRE1C,CHMP2B,ARL5B,EIF3H,USP36,SRSF1,GLOD4,DNAJC10,DHX16,PLEKHG4B,CLK3,RBL1,STK38,MAFK,FASTK,UHRF2,DNAJC17,AP1S1,XRCC3,NCOA1,USP53,SMAD4,RAD51D,PARD3,INTS2,BCL2L12,MCM10,SMAP1,GOLIM4,CDT1,ARID5A,SMC6,NKRF,HMGN3,ARF1,CSNK1A1,SCYL2,DNAJB9,TFRC,FZD6,PTPN2,HERC3,GSTK1,IRF4,ABCD1,SS18L1,DDX31,ORC3,CAMK2G,RNF5,RPAP3,CNTN5,RHOA,HMGN5,SNX2,ABCF2,TOP3A,ARHGEF12,PCGF1,DDX23,RAB18,TRIM26,KPNA4,PDCD6,FBXO41,ATP6V1D,BIRC5,TFE3,NEIL3,E2F1,PGRMC1,USP20,IMPDH1,RBPJ,NR2F2,PGAM1,RPS6KC1,UBE2C,HIPK3,NUP188,MAX,PDCD6IP,GXYLT1,ADAM10,CXXC1,TSC22D3,USP39,CUL1,CCNB1,IKBIP,UBE2I,PARK7,PA2G4,ASAP2,RAB4A,SUCLG2,TAF5L,CDC25B,TFG,PLCL2,SMARCE1,DNMT1,CDC5L,NOL12,ORAI2,USO1,KLF10,AKT2,PBK,GNG7,MKI67,DDX20,SLC17A5,AURKB,USP22,CCNF,RFC2,CBFB,SLC25A5,RAB2B,EIF3A,DOT1L,ZMYM3,MAP3K4,ANKRD10,HHEX,WAS,TPP2,ITGB1,PTPN7,PTPDC1,TRAF5,ZMAT3,HDAC2,PTOV1,DDX58,RECQL,COX5B,DNAJC5,CHTF18,GSPT2,VAV2,PRKAA1,RRM1,KIF23,CYCS,NOTCH2,PSEN1,JMY,CNOT3,CFLAR,FKBP1A,RPN1,RNF121,MEX3C,SNX18,ATIC,HDAC7,PPP4R1,MSH2,DAPK1,FBXL7,CYC1,PIKFYVE,RNF135,GNAI2,LPCAT1,ANKHD1,EEF1D,MORC3,TERF2,SOCS5,PHF10,DDX28,PIGT,PRIM2,PIP4K2C,MFNG,SEPT8,RIT1,ARID1A,KDM3A,MAP2K2,PHF6,AKAP1,FAS,PI4K2A,XRCC5,HMGN2,ADSS,CAT,DERL1,PFDN5,TMEM54,ZFP92,RBMX,QARS,ACLY,PIAS2,FAM83D,USP32,PPP3R1,ARAP1,VCPIP1,TCOF1,GPI,YY1,MAP3K5,RNF14,CDK2,NRBP1,CDKN2A,TP53RK,DNMT3A,REPS2,RAB11B,TRIP10,URB2,SF3B1,RAF1,SUZ12,RPS6KA1,MAGED1,RAC1,POMP,BCL2L1,SDHA,GNB2,EPM2A,PHC2,CRKL,FLAD1,TERF2IP,MOAP1,CCNA2,ZNF75D,SHC1,KDM2A,RALB,MTMR4,SIAH1,LPIN2,SOCS6,TNPO2,CDKN1B,AQR,TP53BP2,TALDO1,CDK12,SAP30,CCT2,ATP13A1,BRD4,RFC3,MAPRE2,HMGN4,ERF,NARF,CUL3,LRRC8A,PKMYT1,CDC23,ASB13,GAR1,POLG2,ERC1,EML4,TRIM28,DHX57,SUPT16H,RAD51C,HSPA4,PPP2R5A,JAK1,ACYP1,SAFB,STAT1,SEL1L,FTSJ1,H2AFX,BEND3,TRIM32,PDCD11,XRCC4,POLQ,PRPF4B,ADAM23,RHEBL1,OTUD5,NCOR2,MECP2,TCF3,CBLL1,BLM,POFUT1,HMG20A,FOXO3,RAB11A,HEATR5B,MAD2L2,JAKMIP1,EBP,WWP2,PIP5K1C,RBM17,DNAJC8,PTEN,AHSA1,AXIN2,PTPN11,COPS7B,NDUFA3,CNPY3,UBE2M,NCOA2,MSH6,SMC4,JMJD4,LONRF3,NET1,NEK7,ILF3,RABIF,ADSL,FBXO9,ANAPC2,LRRC1,RHOT1,KIF11,MARK2,TSR2,FADD,CBX3,PLD3,FBXO21,GNA12,TMEM127,TTLL4,PFDN4,MFAP1,TFDP1,STX18,KHSRP,PPP1R11,CCDC69,DDX5,DUSP11,BRWD3,ESPL1,DDB1,GPR89B,IPO4,DEF6,POLA2,MIB2,RORB,PIGM,IER2,UBE2E2,ST13,NF1,HMGXB3,MOGS,PTP4A3,UBE2Q1,TAF6L,AGFG1,SIRT2,KIF2C,FKBP2,USP48,UBQLN2,MAPK14,BECN1,RNF103,MBD4,ZNF804A,RAP1A,CDC42,EIF4A3,THADA,JAZF1,IMPAD1,RAB35,PPP1R12C,RP2,TCEA1,OGG1,ARID4A,TRIM14,SRPK2,COPS8,FYTTD1,TDP1,TRIM8,SNRNP200,NCK1,VHL,RRM2,WDR82,PITPNB,KMT2C,SOX4,STK17B,UBTF,CXXC4,GEMIN5,PAF1,UEVLD,SPATA2,PPM1G,PQBP1,BAZ1B,CAB39,STK11,CLU,CHEK2,COPS6,MRPL13,CHPT1,CAPN1,SLC12A7,UBE2D3,PIGN,PPP1R2,PPP1R12A,TM9SF4,NACA,CIB1,PCSK7,MED13L,THRAP3,RGS2,XPO7,EPHX2,NUP205,NFATC3,ZNF449,GLTP,BCL2,KIFAP3,KNTC1,UBE3C,ZRANB1,MCPH1,SLC12A2,N4BP2,CSNK1G3,HP1BP3,ALDH9A1,ZNF189,OXR1,DAPK3,ARHGAP15,ISG15,CAND1,MASTL,GNAS,UAP1,KLHL15,CDCA5,SIAH2,SLC16A1,FN3KRP,KIAA1328,PITPNA,YWHAZ,NUP62,RBBP4,TOB1,APOL2,PTDSS1,ZBTB24,SMARCD1,MBD1,TCF12,WASF2,PRKAB1,SNX27,ASH1L,CORO7,MDH2,PMS2,SMARCA4,PLAGL2,ORC1,TWF2,CHD1,MXD1,USP5,CCDC50,SAR1A,AKAP8,PPP6C,CS,RPN2,APOOL,FAM3A,SCYL3,ABI1,DNAL4,EBAG9,MOSPD1,RLIM,POU2AF1,SELPLG,RNF25,PCGF6,METTL2A,GLO1,OGDH,BICD2,FANCE,PDHX,RAD54B,DAP3,DUS3L,HNRNPR,TAB2,HPS5,STAT6,TULP3,WDR59,FKBP5,SCARB1,TMEM101,GAS2,USP11,SMURF1,MAPK1,PPP2R2D,CBX4,DNAJC2,CDS2,MAGEH1,TRIP12,SH2D3A,CASP6,EYA1,RAE1,SCYL1,NUP54,DBF4,CHIC2,LETMD1,MXD4,MYO9B,PIP4K2A,XPR1,RGS1,FBXO5,KIF5B,FGFR3,CTNNBL1,TANK,ARHGEF2,ERI3,STAT3,FRMD8,MYO5A,AMPD2,TELO2,CSNK1G2,ADAM17,HMGN1,ASPM,MEN1,TFEB,MAPK3,MTMR3,ATAD2,ZC3H7B,COX8A,DTX4,SRSF3,ZMIZ1,PLOD3,PREPL,IDH3B,TERF1,HRAS,RAB3IL1 |
| 4.118e-20 | -44.64 | non_small_cell_carcinoma | COSMIC cancer mutations | non_small_cell_carcinoma | 5292 | 988 | 17385 | 2587 |
RAB14,FGFR1OP,KDM4A,ABCC10,PIGQ,XIAP,DHX8,LACTB2,PPP1R16B,RBM4,ZNF275,FBXO22,EEF2K,CDKN2C,CDK5,NEK6,RABGAP1L,RAD23B,SRSF4,UPRT,NUP153,RNF26,SENP1,PCBP2,MLST8,PLK3,BAK1,ZNF672,CCDC57,ERCC1,ZNF559,RHOBTB3,NRAS,GABPA,MCL1,TOPORS,PLEKHM3,SMC2,PPFIA3,MCM2,ICMT,RAB22A,ARF4,KRIT1,TRIM47,SMAD2,MID1IP1,WDR11,RAD18,PDRG1,LIMK1,AXIN1,OGT,RNASEL,FBXL3,TFDP2,SMAD1,E2F2,PDCD4,PFKP,NXT2,SSRP1,DDX42,CLSPN,KIAA0100,PHF23,RHOC,TRIO,RAB23,CERK,TOP2B,EZH1,EIF2AK4,PDCD7,ITGB5,APH1B,HAUS2,LMNA,MCTS1,ATG4A,DDX56,SLC38A5,RNFT1,INTS7,INPP5A,MCM5,FBXO7,PHF14,ZNF326,FOXN2,GEMIN4,NUP85,PHKG2,SRSF11,IFRD1,ETV3,FOXK1,PRRC2A,DHX29,MTA2,GTPBP4,MYBL2,ITM2A,USP10,BCLAF1,SRSF5,MTX1,MPG,ELK1,EIF4H,ABCF1,RHOB,PTPRF,MAGED2,DTWD1,KPNA1,ETS2,DUSP3,MDH1,SNX14,RNF139,ALS2,EGLN1,RHOG,TRIM41,TRERF1,PTTG1,CHD1L,TPX2,MYH9,NUF2,PRKACA,SAFB2,KTN1,RAB21,PRKD3,FBXL6,ZNF420,SH3BP1,DUT,MTA1,UBA5,DDA1,ZCCHC2,NUP107,SEPT11,ANAPC7,RNF19A,MAVS,RBM15,ARL5A,SNX8,GOPC,IDH3A,MAP4K4,CIRBP,E2F3,MEF2D,DNAJA1,RAB1A,TAZ,FKBP3,DDX17,KIF2A,TAF2,PPP2CA,CDC16,LSM6,CORO1C,HIPK2,WDR7,RNF38,DMWD,FUS,PDXK,PPP5C,GEN1,USP13,ANXA6,SRSF6,SESTD1,CCM2,TRAK1,SIKE1,ABHD14B,UBE4A,IP6K2,IL21R,ETS1,IFT27,SLC25A43,NEIL2,PPP1R3B,FBXO3,RPA2,ERH,PDCD10,CLIC4,ITGB8,SUV39H2,GATC,HUWE1,PPP1R8,ARF5,ARHGEF1,GEMIN6,UBE3B,FBXL19,GTF2H2,TPCN1,S100A6,IMPA2,LDHB,PDPK1,STAU1,PPP3CA,TK1,TNFAIP3,DDX24,POLK,LDHA,MTMR12,RAB3IP,DDX39A,PICALM,RPA1,SH3BP5,KEAP1,MAGT1,POLE,CCDC6,WNT5B,PITX1,MAPK6,FAM3C,PML,AEN,HMGB2,RGL1,WDR76,CD81,YWHAH,IGBP1,FAF1,ANAPC4,TMEM131,COX15,DDX47,THOC1,WDR13,TRIM11,PPP1R15B,SNX15,CSNK2A1,GIT2,BIRC2,FANCI,PRNP,FANCL,ABL2,RAB8A,PCNA,NUP210,NT5DC1,IL6ST,PIK3R2,XRCC2,ETV6,MYBL1,MCMBP,ASB6,PTPRK,VPS13B,PLK1,SP3,PTPN18,CELSR2,SEPT9,MIOS,RBX1,PBXIP1,SNRPB,RAD51AP1,TLK1,GMFB,LNX2,EZR,CDC6,LRP5,UBE2V1,UTP3,PBRM1,BRCA1,ANLN,RAB5B,USP21,RHEB,TRIM4,SEPT1,FBXO28,CHD3,E2F4,SOCS4,BCL7C,ADAM9,KPNA2,ACTB,PIEZO1,DVL1,NUDT11,POT1,NUMB,FUBP1,HJURP,PHB2,DNAJB2,NKD2,LAMTOR3,KLC1,RACGAP1,COX4I1,ADCK5,CDK13,RAB6A,DNAJB1,PPP3CB,RSAD1,RAPGEF6,RB1,NUS1,VMP1,MBD2,XPA,SLC27A4,RBM3,AFF1,MAML1,CYTH1,ABHD2,TRAPPC9,NSDHL,ACSL3,LDB1,CAMSAP1,UTP15,KRAS,EIF2AK1,MAP4K3,UBE4B,ICAM2,ARPC1A,EIF4G2,IRF5,SDHB,MBIP,PCM1,CDC27,SYNCRIP,PALB2,COX7A2L,PRPS2,ZDHHC7,RUVBL2,BTBD10,CCNB2,BCCIP,USP7,SART1,TRAF7,SUCLG1,ARID2,FOXM1,XAB2,SUMO2,LAGE3,PCBP1,LYN,DUSP22,BCAP31,RAD23A,RPL11,VAV1,MRPL50,CSDE1,PDK2,PSMA6,MDM2,WDR44,PIN1,PDCD2,CORO1A,MINPP1,AHCYL1,STRAP,SAP30L,SPSB3,DVL2,SNX25,KDM3B,ARHGAP17,MND1,BIRC3,BTG2,RAB7A,DNAJC9,NUP155,DCLRE1C,CHMP2B,ARL5B,EIF3H,USP36,SRSF1,GLOD4,DNAJC10,DHX16,PLEKHG4B,CLK3,RBL1,STK38,MAFK,FASTK,UHRF2,DNAJC17,AP1S1,XRCC3,NCOA1,USP53,SMAD4,RAD51D,PARD3,INTS2,BCL2L12,MCM10,SMAP1,GOLIM4,CDT1,ARID5A,SMC6,NKRF,HMGN3,ARF1,CSNK1A1,SCYL2,DNAJB9,TFRC,FZD6,PTPN2,HERC3,GSTK1,IRF4,ABCD1,SS18L1,DDX31,ORC3,CAMK2G,RNF5,RPAP3,CNTN5,RHOA,HMGN5,SNX2,ABCF2,TOP3A,ARHGEF12,PCGF1,DDX23,RAB18,TRIM26,KPNA4,PDCD6,FBXO41,ATP6V1D,BIRC5,TFE3,NEIL3,E2F1,PGRMC1,USP20,IMPDH1,RBPJ,NR2F2,PGAM1,RPS6KC1,UBE2C,HIPK3,NUP188,MAX,PDCD6IP,GXYLT1,ADAM10,CXXC1,TSC22D3,USP39,CUL1,CCNB1,IKBIP,UBE2I,PARK7,PA2G4,ASAP2,RAB4A,SUCLG2,TAF5L,CDC25B,TFG,PLCL2,SMARCE1,DNMT1,CDC5L,NOL12,ORAI2,USO1,KLF10,AKT2,PBK,GNG7,MKI67,DDX20,SLC17A5,AURKB,USP22,CCNF,RFC2,CBFB,SLC25A5,RAB2B,EIF3A,DOT1L,ZMYM3,MAP3K4,ANKRD10,HHEX,WAS,TPP2,ITGB1,PTPN7,PTPDC1,TRAF5,ZMAT3,HDAC2,PTOV1,DDX58,RECQL,COX5B,DNAJC5,CHTF18,GSPT2,VAV2,PRKAA1,RRM1,KIF23,CYCS,NOTCH2,PSEN1,JMY,CNOT3,CFLAR,FKBP1A,RPN1,RNF121,MEX3C,SNX18,ATIC,HDAC7,PPP4R1,MSH2,DAPK1,FBXL7,CYC1,PIKFYVE,RNF135,GNAI2,LPCAT1,ANKHD1,EEF1D,MORC3,TERF2,SOCS5,PHF10,DDX28,PIGT,PRIM2,PIP4K2C,MFNG,SEPT8,RIT1,ARID1A,KDM3A,MAP2K2,PHF6,AKAP1,FAS,PI4K2A,XRCC5,HMGN2,ADSS,CAT,DERL1,PFDN5,TMEM54,ZFP92,RBMX,QARS,ACLY,PIAS2,FAM83D,USP32,PPP3R1,ARAP1,VCPIP1,TCOF1,GPI,YY1,MAP3K5,RNF14,CDK2,NRBP1,CDKN2A,TP53RK,DNMT3A,REPS2,RAB11B,TRIP10,URB2,SF3B1,RAF1,SUZ12,RPS6KA1,MAGED1,RAC1,POMP,BCL2L1,SDHA,GNB2,EPM2A,PHC2,CRKL,FLAD1,TERF2IP,MOAP1,CCNA2,ZNF75D,SHC1,KDM2A,RALB,MTMR4,SIAH1,LPIN2,SOCS6,TNPO2,CDKN1B,AQR,TP53BP2,TALDO1,CDK12,SAP30,CCT2,ATP13A1,BRD4,RFC3,MAPRE2,HMGN4,ERF,NARF,CUL3,LRRC8A,PKMYT1,CDC23,ASB13,GAR1,POLG2,ERC1,EML4,TRIM28,DHX57,SUPT16H,RAD51C,HSPA4,PPP2R5A,JAK1,ACYP1,SAFB,STAT1,SEL1L,FTSJ1,H2AFX,BEND3,TRIM32,PDCD11,XRCC4,POLQ,PRPF4B,ADAM23,RHEBL1,OTUD5,NCOR2,MECP2,TCF3,CBLL1,BLM,POFUT1,HMG20A,FOXO3,RAB11A,HEATR5B,MAD2L2,JAKMIP1,EBP,WWP2,PIP5K1C,RBM17,DNAJC8,PTEN,AHSA1,AXIN2,PTPN11,COPS7B,NDUFA3,CNPY3,UBE2M,NCOA2,MSH6,SMC4,JMJD4,LONRF3,NET1,NEK7,ILF3,RABIF,ADSL,FBXO9,ANAPC2,LRRC1,RHOT1,KIF11,MARK2,TSR2,FADD,CBX3,PLD3,FBXO21,GNA12,TMEM127,TTLL4,PFDN4,MFAP1,TFDP1,STX18,KHSRP,PPP1R11,CCDC69,DDX5,DUSP11,BRWD3,ESPL1,DDB1,GPR89B,IPO4,DEF6,POLA2,MIB2,RORB,PIGM,IER2,UBE2E2,ST13,NF1,HMGXB3,MOGS,PTP4A3,UBE2Q1,TAF6L,AGFG1,SIRT2,KIF2C,FKBP2,USP48,UBQLN2,MAPK14,BECN1,RNF103,MBD4,ZNF804A,RAP1A,CDC42,EIF4A3,THADA,JAZF1,IMPAD1,RAB35,PPP1R12C,RP2,TCEA1,OGG1,ARID4A,TRIM14,SRPK2,COPS8,FYTTD1,TDP1,TRIM8,SNRNP200,NCK1,VHL,RRM2,WDR82,PITPNB,KMT2C,SOX4,STK17B,UBTF,CXXC4,GEMIN5,PAF1,UEVLD,SPATA2,PPM1G,PQBP1,BAZ1B,CAB39,STK11,CLU,CHEK2,COPS6,MRPL13,CHPT1,CAPN1,SLC12A7,UBE2D3,PIGN,PPP1R2,PPP1R12A,TM9SF4,NACA,CIB1,PCSK7,MED13L,THRAP3,RGS2,XPO7,EPHX2,NUP205,NFATC3,ZNF449,GLTP,BCL2,KIFAP3,KNTC1,UBE3C,ZRANB1,MCPH1,SLC12A2,N4BP2,CSNK1G3,HP1BP3,ALDH9A1,ZNF189,OXR1,DAPK3,ARHGAP15,ISG15,CAND1,MASTL,GNAS,UAP1,KLHL15,CDCA5,SIAH2,SLC16A1,FN3KRP,KIAA1328,PITPNA,YWHAZ,NUP62,RBBP4,TOB1,APOL2,PTDSS1,ZBTB24,SMARCD1,MBD1,TCF12,WASF2,PRKAB1,SNX27,ASH1L,CORO7,MDH2,PMS2,SMARCA4,PLAGL2,ORC1,TWF2,CHD1,MXD1,USP5,CCDC50,SAR1A,AKAP8,PPP6C,CS,RPN2,APOOL,FAM3A,SCYL3,ABI1,DNAL4,EBAG9,MOSPD1,RLIM,POU2AF1,SELPLG,RNF25,PCGF6,METTL2A,GLO1,OGDH,BICD2,FANCE,PDHX,RAD54B,DAP3,DUS3L,HNRNPR,TAB2,HPS5,STAT6,TULP3,WDR59,FKBP5,SCARB1,TMEM101,GAS2,USP11,SMURF1,MAPK1,PPP2R2D,CBX4,DNAJC2,CDS2,MAGEH1,TRIP12,SH2D3A,CASP6,EYA1,RAE1,SCYL1,NUP54,DBF4,CHIC2,LETMD1,MXD4,MYO9B,PIP4K2A,XPR1,RGS1,FBXO5,KIF5B,FGFR3,CTNNBL1,TANK,ARHGEF2,ERI3,STAT3,FRMD8,MYO5A,AMPD2,TELO2,CSNK1G2,ADAM17,HMGN1,ASPM,MEN1,TFEB,MAPK3,MTMR3,ATAD2,ZC3H7B,COX8A,DTX4,SRSF3,ZMIZ1,PLOD3,PREPL,IDH3B,TERF1,HRAS,RAB3IL1 |
| 4.213e-20 | -44.61 | GSE9006_TYPE_1_VS_TYPE_2_DIABETES_PBMC_AT_DX_UP | MSigDB lists | GSE9006_TYPE_1_VS_TYPE_2_DIABETES_PBMC_AT_DX_UP | 186 | 80 | 17377 | 2626 |
SART1,RWDD1,RPLP2,DCAF15,UBN1,XAB2,IRF3,SAFB2,RPL11,HNRNPA2B1,PIN1,MTA1,NOC2L,CORO1A,TECR,ILKAP,CFL1,HTRA2,TACC3,CDC37,PRPF19,CLPTM1,ARHGAP17,ATP13A1,DRAP1,MRPL12,SLC25A22,EDF1,PEF1,TRIM28,PAF1,BRMS1,RPL37,PEX5,CDCA4,ATP1A1,SAFB,TBL3,SH3GLB2,DNAJC17,H2AFX,RRS1,NAA60,SSRP1,PPIB,NADSYN1,ANXA6,MRPS2,PDAP1,CDK2AP2,TKT,KLF13,SDF2L1,MFSD10,CNOT3,SAC3D1,ERH,ARF5,BANF1,ARHGEF1,COPS7B,CNN2,UBE2M,MED22,HNRNPM,EEF1D,PDLIM2,RBM42,TSTA3,WDR18,ANAPC2,SF3A2,RPL36,FBXO41,GPS2,LPCAT4,PPP6R2,SNRNP70,CD81,HRAS |
| 4.824e-20 | -44.48 | TOYOTA_TARGETS_OF_MIR34B_AND_MIR34C | MSigDB lists | TOYOTA_TARGETS_OF_MIR34B_AND_MIR34C | 405 | 134 | 17377 | 2626 |
CCDC93,HNRNPAB,GNPDA1,TMEM109,ZNF107,KIF2C,SLC29A1,CCNB1,PABPC4,KIFC1,PA2G4,NUP210,IMPAD1,ZNF639,XRCC2,SRSF4,SRSF10,PLK1,MIOS,APH1A,MKI67,KIF15,RRM2,CKAP2L,AURKB,DIDO1,CCNF,FOXRED1,RFC2,LUC7L,ASF1B,KRIT1,SMAD2,PDRG1,SH3GLB2,FAM72C,CLSPN,CENPF,DHX9,HAUS4,PARN,PITHD1,RAPGEF6,PDXDC1,RAVER2,DTL,NFATC3,EIF2S2,PPP4R1,TNPO3,LPCAT1,FAM171A1,VOPP1,EIF5A,ABHD2,ERLIN1,MYBL2,ARID1A,TOMM40,LY6E,ABCF1,YWHAZ,SMPD4,RBBP4,PPP6R2,SNRNP70,MZT2B,FAM72D,BCCIP,MPHOSPH8,FOXM1,VTI1A,TMEM97,TCF19,USP5,ZNF473,CCNA2,ATP2A2,STRBP,KIF14,BCAP29,ANAPC7,METTL9,SAP30L,PRPF19,ANKLE2,PSRC1,RFC3,HMGN4,KAT7,CDCA2,NUSAP1,DCLRE1C,PKMYT1,SHCBP1,ZNF700,CANT1,KLHDC4,B4GALT3,REEP4,GEN1,TUBB,RAD51D,CWC25,SHPRH,VPS45,FLOT1,WWP2,GOLM1,RBM17,CENPJ,SLC35B4,GTSE1,COPS7B,UPF2,TAGLN2,CNPY3,MED22,PPAN,ZNF202,LDHA,ILF3,RAB3IP,KIF11,API5,BORA,ARL17A,TSR2,POLE,TTLL4,TFDP1,SLC25A19,C4orf46,IDH3B |
| 4.827e-20 | -44.48 | ZHANG_TLX_TARGETS_60HR_DN | MSigDB lists | ZHANG_TLX_TARGETS_60HR_DN | 259 | 99 | 17377 | 2626 |
SRM,POLA2,IVNS1ABP,UCK2,SMARCA4,NUF2,KIF2C,ORC1,TCF19,POLR3K,FANCI,MRPL50,CCNA2,UCHL5,DUT,NUP107,KIF22,TARDBP,TIPARP,DNMT1,TACC3,PLK1,RFC3,PPP1R18,AATF,RAD51AP1,PBK,NSUN2,MKI67,RRM2,DDX20,WDHD1,NUP155,CDC6,AURKB,BRCA1,SMC2,MCM2,ANLN,SHCBP1,ASF1B,SRSF1,PRIM1,RAD51C,HSPA4,RAD18,HNRNPR,RBL1,CEP55,ANP32E,FKBP5,SASS6,DNAJC2,MCM10,HJURP,CDT1,CENPF,DBF4,RRM1,SMC6,RACGAP1,SDF2L1,THRAP3,BLM,NCAPG,SPAG5,DTL,LYAR,RPA2,C12orf10,GART,INTS7,MCM5,TIMELESS,CENPM,SLC12A2,NUP85,MSH6,SMC4,GINS1,TK1,NASP,PRIM2,NET1,AMD1,MYBL2,KIF11,MASTL,EPRS,NAP1L1,SYNCRIP,POLE,BIRC5,DCK,CDCA7L,CDCA5,HMGB2,SRSF3,CCNB2 |
| 7.355e-20 | -44.06 | KIM_BIPOLAR_DISORDER_OLIGODENDROCYTE_DENSITY_CORR_UP | MSigDB lists | KIM_BIPOLAR_DISORDER_OLIGODENDROCYTE_DENSITY_CORR_UP | 644 | 186 | 17377 | 2626 |
HNRNPAB,ADD1,GNPDA1,AP3M2,AGPAT1,ENSA,CUL1,GLUD1,GYG1,CDIPT,SEC16A,PPP1R16B,ABHD14A,RNF103,SF3B2,PRNP,CDK5,GOT2,DPYSL2,RAD23B,SRI,AKR1B1,AP2B1,TRA2B,MARCH2,ABCC5,PTPRK,GMFB,PRPSAP1,CLNS1A,OPTN,MAN2A2,RPL37,TMED10,RPS27A,PSMD8,COX5A,UQCRH,ATP6V0C,PSMC1,MYL12B,OAZ1,PTOV1,LZTR1,PHB2,NACA,CTCF,XPO7,PDXDC1,MYL6B,NDUFS7,NDUFS4,FKBP1A,RPN1,SUB1,MLX,DAD1,RIMS3,YBX1,KIFAP3,AHCY,CYC1,MRPL40,ATP6V0D1,CYFIP1,FTL,RPS10,SEPT8,ITM2A,RPS24,CYFIP2,CCT8,PSMB3,NCDN,XRCC5,GNAS,PFDN5,POLR2J,NSF,COX7A2L,LPCAT4,CABIN1,PTDSS1,NUDT3,EXOC3,NDUFA5,SUCLG1,EIF3D,MAGED1,SUMO2,STARD7,ATP6V1B2,SNN,DAZAP2,SDHA,RPL11,MOAP1,SEC11A,FARSA,ATP6V0B,APLP2,ATP2A2,PIN1,LPIN2,CLCN6,PPP6C,CORO1A,CLTB,TALDO1,CFL1,DCTN1,GPX4,CCT2,SHOC2,RPL29,RPL35,SEC61B,EID1,DRAP1,WBP2,CIRBP,MTMR6,GLO1,TMEM147,NDUFB1,TRIM28,EIF3G,EIF3K,CDC16,HINT1,SCAP,GOLGA8A,WDR7,RPLP1,FAU,LTA4H,AP2S1,MIF,SLC30A9,ANXA6,SCAMP3,KLHL21,TKT,ARFIP2,SLC25A12,LANCL1,PMVK,PIP5K1C,FGFR3,PSMD2,NDUFV1,SLC1A4,AHSA1,ARF5,H2AFY,ARHGEF2,NDUFS8,ERI3,FBL,CAMK2G,LDHB,MOB4,HMGN1,RHOA,RPL8,TUFM,HAGH,FADD,ECH1,PRDX1,SH3BP5,NUCB1,RPL32,ELMO1,TFE3,PGRMC1,DTX4,PPP1R11,ACADM,PSAP,IDH3B,IGBP1,TAF6,CD81,HRAS,DDB1 |
| 9.311e-20 | -43.82 | Cell Cycle, Mitotic | REACTOME pathways | R-HSA-69278 | 514 | 166 | 10287 | 1696 |
POLA2,FGFR1OP,MAX,H2AFZ,NUP188,ENSA,CUL1,CSNK2A1,KIF2C,CCNB1,MIS12,LIN9,CDKN2C,RAB8A,PCNA,PSMD1,NUP210,NEK6,PDS5B,NUP153,CDC25B,SEH1L,PLK1,USO1,RBX1,AKT2,RRM2,CDC6,AURKB,SMC2,MCM2,RFC2,GINS4,OPTN,PRIM1,RPS27A,PSMD8,E2F4,TFDP2,E2F2,PSMC1,AAAS,MAPRE1,PPP1R12A,GORASP1,CENPF,KIF23,HAUS4,PMF1,PSMD9,HAUS2,NUP205,LMNA,RB1,SMC3,CCP110,MCM5,BANF1,FBXL7,KNTC1,MCPH1,NUP85,PRIM2,MYBL2,PSMA1,GORASP2,PSMB3,PSMC4,HAUS8,MASTL,PCM1,GOLGA2,CDC27,ODF2,CDCA5,NUP62,RBBP4,NDE1,CDK2,CCNB2,NUP58,CDKN2A,NDC1,FOXM1,DYNLL1,PTTG1,TPX2,NUF2,ORC1,PRKACA,PSMA6,AHCTF1,CCNA2,LPIN2,NUP107,CDKN1B,ANAPC7,CEP63,DCTN1,ANKLE2,RFC3,PSMA8,TAOK1,TUBGCP5,PSMB7,E2F3,NUP155,PKMYT1,CDC23,RAB1A,H2AFV,PSMB9,CENPU,PPP2CA,KIF2A,CDC16,PPP2R5A,DSN1,RBL1,PSMD3,H2AFX,H3F3A,MAPK1,PPP2R2D,TUBB,CSNK1D,MCM10,RAE1,CDT1,DCTN2,DBF4,NUP54,CDCA8,SPDL1,CDK11B,NCAPG,TUBGCP2,FBXO5,RPA2,PSMD2,CENPJ,KMT5A,GTSE1,CENPM,ORC3,SMC4,NUDC,GINS1,NEK7,ANAPC2,RANGAP1,BORA,CDK11A,MAPK3,RPA1,LEMD2,KIF18A,POLE,BIRC5,TFDP1,E2F1,SSNA1,CENPT,UBE2C,ESPL1,ANAPC4 |
| 9.531e-20 | -43.80 | protein localization to organelle | biological process | GO:0033365 | 614 | 180 | 17256 | 2622 |
POLA2,TXN,NUP188,MTX3,TSC2,SEC16A,BECN1,PARK7,MIS12,RPL23A,CDK5,SNUPN,TIMM23,RAB35,RPF2,NUP153,CARM1,TIMM50,PLK1,SRP72,LARS,NOL8,MRNIP,TOPORS,NUTF2,AURKB,ANLN,ARF4,OPTN,RPL37,PAF1,HHEX,TRAM2,TIMM13,RPS27A,TIMM29,RPS14,MIA2,KPNA2,CLU,DVL1,VPS4A,RRS1,SLF1,RPS26,POT1,LONP2,NXT2,RPS15,MAPRE1,SEC61G,PHB2,DHX9,CTCF,RPL15,TIA1,RAB6A,SUPT7L,VPS25,LMNA,SPAG5,RTKN,RB1,FBXO7,XPA,TNPO3,YBX1,PIKFYVE,MCPH1,LRSAM1,NUP85,MORC3,TERF2,KDELR1,NAGPA,TIMM8B,GCC2,RPL6,RPS10,RPS24,MTX1,TOMM40,PTTG1IP,XRCC5,RPL36,SCARB2,KPNA1,PCM1,LAMTOR4,FAM83D,PPP3R1,NUP62,RUVBL2,SGF29,NUP58,TOMM20,RPLP2,TOR1AIP1,VTI1A,RPAIN,BCAP31,RPL11,MOAP1,TERF2IP,MDM2,SP100,NUP107,TNPO2,BCAP29,ANKRD13C,ARL5A,RPL29,SEC61B,NXT1,RPL35,RAB7A,INTS13,RPL38,TOR1AIP2,NUP155,BICD2,DNAJA1,ARL5B,TOLLIP,RPS9,RPSA,PEX5,HSPA4,CHMP4A,SEC61A1,CCDC14,TIMM17A,TULP3,ARNTL,RPLP1,CHMP4B,SMURF1,PITRM1,CSNK1D,RPS2,KLHL21,RAE1,DCTN2,SRGN,NUP54,TIMM21,SPDL1,RAB11A,WRB,RPA2,RPL17,NABP2,DCP1A,H2AFY,RPL19,STAT3,MTX2,TGFB1,PPP3CA,TNFAIP3,RPL8,RANGAP1,PACS1,RPL27A,SH3GLB1,RPA1,MFN2,LEMD2,ATP6V1D,HGS,KPNA4,RPL32,OSBPL8,PML,CENPT,SPCS3,CD81,CHMP7,SLF2,IPO4 |
| 1.078e-19 | -43.67 | MORF_DNMT1 | MSigDB lists | MORF_DNMT1 | 112 | 58 | 17377 | 2626 |
POLA2,IMMT,MAPRE1,H2AFZ,NUP188,RRM1,EBNA1BP2,XPO7,STMN1,PABPC4,HDDC2,SPAG5,RAD23A,HNRNPA2B1,SMC3,IARS,GOT2,MCM5,DUT,MRPS27,CS,TNPO3,TRA2B,ANP32A,TARDBP,TCEA1,PTGES3,PDIA6,DNMT1,HNRNPM,NUDC,SNRNP200,NASP,PRKDC,PPIE,VDAC2,DNAJC9,SLBP,MCM2,TXNL4A,CBFB,CDK11A,SNRPA,TARS,CHAF1A,SRSF1,XRCC5,HNRNPR,SAFB,PPM1G,TFDP1,LRPPRC,BAZ1B,KHSRP,RUVBL2,ESPL1,HDAC2,SSRP1 |
| 1.081e-19 | -43.67 | protein modification process | biological process | GO:0036211 | 3147 | 648 | 17256 | 2622 |
FGFR1OP,KDM4A,MAP3K7CL,PIGQ,XIAP,TGOLN2,FBXO22,EEF2K,CDK5,PSMD1,NEK6,RAD23B,CRY2,NUP153,FNIP2,RNF26,TIPARP,ANKRD9,MGAT5,SENP1,USP34,PLK3,PGAP2,TMEM115,NRAS,EHMT1,MIER2,TOPORS,DCUN1D5,ICMT,ARF4,BRMS1,SMAD2,RAD18,RPS27A,LIMK1,AXIN1,OGT,ATE1,VIPAS39,ST3GAL2,RNASEL,KLHL42,FBXL3,SMAD1,AAAS,ZNF720,CLSPN,TRIO,TOP2B,EZH1,EIF2AK4,ZNRF3,PSMD9,CDC73,ATG4A,DDRGK1,PDXP,RNFT1,FBXO7,NUP85,PHKG2,UBE2QL1,NAGPA,FOXK1,MAPKAPK3,MTA2,ERO1A,MAN1B1,ARMT1,USP10,PTPRF,FNTA,DUSP3,CSK,SETD3,TEX30,PTAR1,WIPI2,CFAP20,SGF29,RNF139,NUP58,EGLN1,TRIM41,KARS,UBR2,WDTC1,RXYLT1,INO80E,PRKACA,STAM,CPNE3,ANKIB1,KTN1,APP,PRKD3,FBXL6,MTA1,DDA1,UBA5,NUP107,ANAPC7,RNF19A,MAVS,ATF2,RPRD1B,RNF169,ULK3,KAT7,MAP4K4,RAB1A,FKBP3,PPP2CA,PEX5,CDC16,NSMCE2,HIPK2,CAMKMT,RNF38,DMWD,PPP5C,USP13,RPS2,ZFP91,CCM2,TRAK1,JMJD6,UBE4A,WDR5,PPP1R3B,GOLM1,FBXO3,PSMD2,SUV39H2,HUWE1,PRDM4,NAA50,LTN1,KANSL2,UBE3B,TTLL12,ST8SIA2,GTF2H2,FBXL19,LYPLA2,SPTAN1,PDPK1,PPP3CA,TNFAIP3,USP42,ZNF862,KEAP1,MAGT1,GPS2,DBI,MAPK6,PML,PARP10,WDR45B,ANAPC4,TRIM11,PPP1R15B,CSNK2A1,BIRC2,ZER1,FANCL,TET3,ABL2,RAB8A,PCNA,NUP210,ASB6,RYBP,PTPRK,CDC37,PLK1,SP3,PTPN18,RBX1,BAZ2A,SNRPB,TLK1,GMFB,UBE2V1,BRCA1,KRTCAP2,PRKRA,USP21,TRIM4,ALG3,CHD3,SOCS4,ARRDC1,ACTB,NGLY1,NAA60,RMND5A,LAMTOR3,SDC2,ADCK5,CDK13,RAB6A,PPP3CB,B4GALT4,RLF,ASXL2,C1GALT1,NUS1,UBE2Q2,MED8,CCP110,PPIL2,CTR9,MDFIC,MAML1,LRSAM1,DCAF8,LDB1,KRAS,EIF2AK1,MAP4K3,RTF1,UBE4B,NFATC2IP,LY6E,METTL22,STYXL1,ZDHHC3,NMT2,PSMC4,MBIP,GALNT2,CDC27,ZDHHC7,PRMT7,RUVBL2,RNF114,USP7,KCTD7,CYLD,TRAF7,SUMO2,LYN,DUSP22,RAD23A,PDK2,PSMA6,MDM2,KMT5C,BRPF3,ABRAXAS2,PIN1,PPME1,MINPP1,LMAN1,SAP30L,CTDSP2,SPSB3,PRPF19,KDM3B,PPIF,BIRC3,PPT1,PSMA8,BTG2,PPIE,MTMR6,NUP155,KDM1B,USP36,CLK3,FASTK,PSMD3,STK38,UHRF2,NCOA1,USP53,SMAD4,ZC3HC1,CTDP1,KLHL21,CDCA8,TMX3,SUMF1,CDK11B,CSNK1A1,SCYL2,PTPN2,HERC3,IRF4,CWC27,CAMK2G,RNF5,CNTN5,RPRD1A,RHOA,PRKDC,RANGAP1,PPWD1,PCGF1,FBXO41,NEK1,GOLGA7,BIRC5,USP20,TAF12,RPS6KC1,UBE2C,HIPK3,GCSH,NUP188,GXYLT1,PRKCSH,ADAM10,ZDHHC8,CXXC1,USP39,CUL1,NHLRC3,CCNB1,UBE2I,PARK7,ASPHD2,FBXW2,TAF5L,MARCH2,CDC25B,MAST2,SEH1L,AKT2,PBK,GALNT7,AURKB,USP22,CCNF,MCFD2,CBFB,DOT1L,MAP3K4,MKNK1,STT3A,PSMD8,TPP2,PTPN7,PTPDC1,ARRB2,ZNF598,HDAC2,B4GALT2,DDX58,WSB2,PPIB,GMFG,DHPS,PRKAA1,B4GALT1,CYCS,MAN2B1,SUPT7L,PSEN1,TMEM165,WDR48,FKBP1A,RNF121,RPN1,KLHL5,ZNRF2,DAD1,HDAC7,PPP4R1,PIGG,DAPK1,TPST1,FBXL7,RNF135,APOL1,MORC3,SOCS5,EIF5A,PIGT,COQ8A,MFNG,ADRB2,KDM3A,MAP2K2,PSMB3,DERL1,GOLGA2,EPOP,CSNK1G1,PPP3R1,USP32,PIAS2,DCAF11,VCPIP1,MAP3K5,YY1,CDK2,RNF14,NRBP1,ZC3HAV1,NDC1,TP53RK,ATXN3,RAB11B,RPS6KA1,RAF1,SUZ12,RAC1,KLHL18,CRKL,APLP2,CCNA2,KDM2A,SHC1,SIAH1,MTMR4,UCHL5,SOCS6,TTC3,ILKAP,CDK12,NAA35,CFL1,SAP30,TAOK1,CUL3,ELP4,KIAA1586,PKMYT1,ASB13,CDC23,PSMB9,TRIM28,SERP1,ERC1,SOCS7,DDOST,PPP2R5A,JAK1,SEL1L,PPA2,BEND3,TRIM32,B4GALT3,EYA2,CSNK1D,PRPF4B,OTUD5,MECP2,MANBA,B4GALT5,BABAM1,CDCA3,BRAP,CBLL1,SDF2L1,RAB11A,POFUT1,WWP2,CCNK,RFWD3,PTEN,FUT8,PTPN11,AXIN2,FEM1B,COPS7B,MAP3K14,CREB1,OSTC,UBE2M,KAT2A,LONRF3,NEK7,ILF3,PARP4,FBXO9,TBRG4,ANAPC2,OTUD3,RHOT1,ARSK,MARK2,FBXO21,NUCB1,HGS,PRDX3,TTLL4,PPP1R11,DUSP11,DDB1,MIB2,CCNC,PIGM,UBE2E2,DCAF15,NF1,KMT2E,MOGS,DNAJC24,PTP4A3,UBE2Z,UBE2Q1,SIRT2,TAF6L,SNRPD3,FKBP2,USP48,BECN1,MAPK14,RNF103,UBLCP1,CDC42,ATG3,JOSD1,SLC35C2,ARID4A,FGFR1OP2,CARM1,TIMM50,SRPK2,COPS8,TRIM8,DPM1,NCK1,VHL,RIOX2,SUMF2,WDR82,KMT2C,STK17B,MAN2A2,PAF1,UEVLD,PPM1G,BAZ1B,CAB39,STK11,CHEK2,ROCK1,GALNT10,COPS6,DCAF5,PSMC1,UBE2D3,PIGN,PPP1R12A,GORASP1,UFC1,MEF2A,RHBDD1,NUP205,DTL,MED10,PYURF,ZNF335,BCL2,ZRANB1,UBE3C,CSNK1G3,PSMA1,SYVN1,EIF2A,VKORC1,DAPK3,ISG15,CAND1,MASTL,KLHL15,SIAH2,FN3KRP,NUP62,NAA20,RBBP4,PRKAB1,TOMM20,ASH1L,MPHOSPH8,WDYHV1,MDH2,NSD3,EXT2,MEAF6,USP5,BABAM2,PPP6C,RPN2,PDIA6,SCYL3,ABI1,RLIM,PGGT1B,RNF25,PSMB7,PCGF6,OGDH,EDEM2,MBD3,BTBD1,TAB2,FKBP5,USP11,SMURF1,MAPK1,PPP2R2D,ABCA1,CBX4,PDF,TRIP12,SH2D3A,RAE1,EYA1,SHPRH,SCYL1,NUP54,DCUN1D4,MAN1A1,FASTKD3,FGFR3,KLHL20,GRK2,KMT5A,PPIG,FBL,SLC35A1,TGFB1,B3GALT6,ZDHHC18,CSNK1G2,DCAF6,HEMK1,MIER1,PRKAR1B,RFFL,RCOR1,PRMT2,MEN1,CDK11A,MAPK3,MTMR3,DTX4,KBTBD7,KMT2B,MBD6,PLOD3,HRAS |
| 1.081e-19 | -43.67 | cellular protein modification process | biological process | GO:0006464 | 3147 | 648 | 17256 | 2622 |
FGFR1OP,KDM4A,MAP3K7CL,PIGQ,XIAP,TGOLN2,FBXO22,EEF2K,CDK5,PSMD1,NEK6,RAD23B,CRY2,NUP153,FNIP2,RNF26,TIPARP,ANKRD9,MGAT5,SENP1,USP34,PLK3,PGAP2,TMEM115,NRAS,EHMT1,MIER2,TOPORS,DCUN1D5,ICMT,ARF4,BRMS1,SMAD2,RAD18,RPS27A,LIMK1,AXIN1,OGT,ATE1,VIPAS39,ST3GAL2,RNASEL,KLHL42,FBXL3,SMAD1,AAAS,ZNF720,CLSPN,TRIO,TOP2B,EZH1,EIF2AK4,ZNRF3,PSMD9,CDC73,ATG4A,DDRGK1,PDXP,RNFT1,FBXO7,NUP85,PHKG2,UBE2QL1,NAGPA,FOXK1,MAPKAPK3,MTA2,ERO1A,MAN1B1,ARMT1,USP10,PTPRF,FNTA,DUSP3,CSK,SETD3,TEX30,PTAR1,WIPI2,CFAP20,SGF29,RNF139,NUP58,EGLN1,TRIM41,KARS,UBR2,WDTC1,RXYLT1,INO80E,PRKACA,STAM,CPNE3,ANKIB1,KTN1,APP,PRKD3,FBXL6,MTA1,DDA1,UBA5,NUP107,ANAPC7,RNF19A,MAVS,ATF2,RPRD1B,RNF169,ULK3,KAT7,MAP4K4,RAB1A,FKBP3,PPP2CA,PEX5,CDC16,NSMCE2,HIPK2,CAMKMT,RNF38,DMWD,PPP5C,USP13,RPS2,ZFP91,CCM2,TRAK1,JMJD6,UBE4A,WDR5,PPP1R3B,GOLM1,FBXO3,PSMD2,SUV39H2,HUWE1,PRDM4,NAA50,LTN1,KANSL2,UBE3B,TTLL12,ST8SIA2,GTF2H2,FBXL19,LYPLA2,SPTAN1,PDPK1,PPP3CA,TNFAIP3,USP42,ZNF862,KEAP1,MAGT1,GPS2,DBI,MAPK6,PML,PARP10,WDR45B,ANAPC4,TRIM11,PPP1R15B,CSNK2A1,BIRC2,ZER1,TET3,FANCL,ABL2,RAB8A,PCNA,NUP210,ASB6,RYBP,PTPRK,CDC37,PLK1,SP3,PTPN18,RBX1,BAZ2A,SNRPB,TLK1,GMFB,UBE2V1,BRCA1,KRTCAP2,PRKRA,USP21,ALG3,TRIM4,CHD3,SOCS4,ARRDC1,ACTB,NGLY1,NAA60,RMND5A,LAMTOR3,SDC2,ADCK5,CDK13,RAB6A,PPP3CB,B4GALT4,RLF,ASXL2,C1GALT1,NUS1,UBE2Q2,MED8,CCP110,PPIL2,CTR9,MDFIC,MAML1,LRSAM1,DCAF8,LDB1,KRAS,EIF2AK1,MAP4K3,RTF1,UBE4B,NFATC2IP,LY6E,METTL22,STYXL1,ZDHHC3,NMT2,PSMC4,MBIP,GALNT2,CDC27,ZDHHC7,PRMT7,RUVBL2,RNF114,USP7,KCTD7,CYLD,TRAF7,SUMO2,LYN,DUSP22,RAD23A,PDK2,PSMA6,MDM2,KMT5C,BRPF3,ABRAXAS2,PIN1,PPME1,MINPP1,LMAN1,SAP30L,CTDSP2,SPSB3,PRPF19,KDM3B,PPIF,BIRC3,PPT1,PSMA8,BTG2,PPIE,MTMR6,NUP155,KDM1B,USP36,CLK3,FASTK,PSMD3,STK38,UHRF2,NCOA1,USP53,SMAD4,ZC3HC1,CTDP1,KLHL21,CDCA8,TMX3,SUMF1,CDK11B,CSNK1A1,SCYL2,PTPN2,HERC3,IRF4,CWC27,CAMK2G,RNF5,CNTN5,RPRD1A,RHOA,PRKDC,RANGAP1,PPWD1,PCGF1,FBXO41,NEK1,GOLGA7,BIRC5,USP20,TAF12,RPS6KC1,UBE2C,HIPK3,GCSH,NUP188,GXYLT1,PRKCSH,ADAM10,ZDHHC8,CXXC1,USP39,CUL1,NHLRC3,CCNB1,UBE2I,PARK7,ASPHD2,FBXW2,TAF5L,MARCH2,CDC25B,MAST2,SEH1L,AKT2,PBK,GALNT7,AURKB,USP22,CCNF,MCFD2,CBFB,DOT1L,MAP3K4,MKNK1,STT3A,PSMD8,TPP2,PTPN7,PTPDC1,ARRB2,ZNF598,HDAC2,B4GALT2,DDX58,WSB2,PPIB,GMFG,DHPS,PRKAA1,B4GALT1,CYCS,MAN2B1,SUPT7L,PSEN1,TMEM165,WDR48,FKBP1A,RNF121,RPN1,KLHL5,ZNRF2,DAD1,HDAC7,PPP4R1,PIGG,DAPK1,TPST1,FBXL7,RNF135,APOL1,MORC3,SOCS5,EIF5A,PIGT,COQ8A,MFNG,ADRB2,KDM3A,MAP2K2,PSMB3,DERL1,GOLGA2,EPOP,CSNK1G1,PPP3R1,USP32,PIAS2,DCAF11,VCPIP1,MAP3K5,YY1,CDK2,RNF14,NRBP1,ZC3HAV1,NDC1,TP53RK,ATXN3,RAB11B,RPS6KA1,RAF1,SUZ12,RAC1,KLHL18,CRKL,APLP2,CCNA2,KDM2A,SHC1,SIAH1,MTMR4,UCHL5,SOCS6,TTC3,ILKAP,CDK12,NAA35,CFL1,SAP30,TAOK1,CUL3,ELP4,KIAA1586,PKMYT1,ASB13,CDC23,PSMB9,TRIM28,SERP1,ERC1,SOCS7,DDOST,PPP2R5A,JAK1,SEL1L,PPA2,BEND3,TRIM32,B4GALT3,EYA2,CSNK1D,PRPF4B,OTUD5,MECP2,MANBA,B4GALT5,BABAM1,CDCA3,BRAP,CBLL1,SDF2L1,RAB11A,POFUT1,WWP2,CCNK,RFWD3,PTEN,FUT8,PTPN11,AXIN2,FEM1B,COPS7B,MAP3K14,CREB1,OSTC,UBE2M,KAT2A,LONRF3,NEK7,ILF3,PARP4,FBXO9,TBRG4,ANAPC2,OTUD3,RHOT1,ARSK,MARK2,FBXO21,NUCB1,HGS,PRDX3,TTLL4,PPP1R11,DUSP11,DDB1,MIB2,CCNC,PIGM,UBE2E2,DCAF15,NF1,KMT2E,MOGS,DNAJC24,PTP4A3,UBE2Z,UBE2Q1,SIRT2,TAF6L,SNRPD3,FKBP2,USP48,BECN1,MAPK14,RNF103,UBLCP1,CDC42,ATG3,JOSD1,SLC35C2,ARID4A,FGFR1OP2,CARM1,TIMM50,SRPK2,COPS8,TRIM8,DPM1,NCK1,VHL,RIOX2,SUMF2,WDR82,KMT2C,STK17B,MAN2A2,PAF1,UEVLD,PPM1G,BAZ1B,CAB39,STK11,CHEK2,ROCK1,GALNT10,COPS6,DCAF5,PSMC1,UBE2D3,PIGN,PPP1R12A,GORASP1,UFC1,MEF2A,RHBDD1,NUP205,DTL,MED10,PYURF,ZNF335,BCL2,ZRANB1,UBE3C,CSNK1G3,PSMA1,SYVN1,EIF2A,VKORC1,DAPK3,ISG15,CAND1,MASTL,KLHL15,SIAH2,FN3KRP,NUP62,NAA20,RBBP4,PRKAB1,TOMM20,ASH1L,MPHOSPH8,WDYHV1,MDH2,NSD3,EXT2,MEAF6,USP5,BABAM2,PPP6C,RPN2,PDIA6,SCYL3,ABI1,RLIM,PGGT1B,RNF25,PSMB7,PCGF6,OGDH,EDEM2,MBD3,BTBD1,TAB2,FKBP5,USP11,SMURF1,MAPK1,PPP2R2D,ABCA1,CBX4,PDF,TRIP12,SH2D3A,RAE1,EYA1,SHPRH,SCYL1,NUP54,DCUN1D4,MAN1A1,FASTKD3,FGFR3,KLHL20,GRK2,KMT5A,PPIG,FBL,SLC35A1,TGFB1,B3GALT6,ZDHHC18,CSNK1G2,DCAF6,HEMK1,MIER1,PRKAR1B,RFFL,RCOR1,PRMT2,MEN1,CDK11A,MAPK3,MTMR3,DTX4,KBTBD7,KMT2B,MBD6,PLOD3,HRAS |
| 1.228e-19 | -43.54 | MORF_RAB1A | MSigDB lists | MORF_RAB1A | 185 | 79 | 17377 | 2626 |
KARS,PRKCSH,RAF1,SUMO2,TOR1AIP1,RAC1,ENSA,BECN1,BCAP31,RNF103,SSR1,TERF2IP,CYHR1,KDM2A,RAD23B,HADHB,RPN2,ZC3H3,EBAG9,SEC61B,DPM1,ATG9A,WBP2,GMFB,RAB1A,RAB5B,SERP1,ARF4,RHEB,SMAD2,PRPF4,COPS6,CLN3,B4GALT3,COIL,MYL12B,SMNDC1,CSNK1D,SEPHS2,COX5B,MRPL9,SEC61G,PDAP1,RAE1,DCTN2,CIB1,SLC4A2,COX4I1,RAB6A,AP3S1,CNOT3,COPB2,SLC25A36,HUWE1,ARPC5,ARF5,MEA1,FAM89B,CAPZA1,ATP6V0D1,TMED2,KDELR1,MORC3,CSNK1G2,TSTA3,JTB,SSR2,GORASP2,PICALM,POLR2A,COX7A2L,GLG1,COX8A,PPP1R11,NUP62,YWHAZ,DUSP11,MDH1,DDB1 |
| 1.408e-19 | -43.41 | BIDUS_METASTASIS_UP | MSigDB lists | BIDUS_METASTASIS_UP | 204 | 84 | 17377 | 2626 |
H2AFZ,NF1,TPX2,UBQLN2,CCNB1,PCBP1,PAIP1,FANCI,MEAF6,CRKL,HNRNPA2B1,RRN3,CCNA2,EIF4A3,RABGAP1L,DNAAF2,TRA2B,NUP153,TARDBP,ATF2,RLIM,COPS8,CCDC57,NRAS,RAB7A,PBK,RRM2,WDHD1,NUSAP1,CDC6,AZI2,CDC23,VDAC1,CBFB,ODC1,RAB22A,ASF1B,SRSF1,PPP2CA,HNRNPR,UBXN2B,MAPK1,SSRP1,TMEM33,USP13,RMND5A,UNK,MCM10,DEPDC1,MRPL42,RAE1,CENPF,DBF4,RRM1,KLC1,CBLL1,RACGAP1,WRB,TFRC,FBXO3,HUWE1,SLC35B4,ATP6V0A2,H2AFY,YBX1,PTGES3,SMC4,PHF10,PRKDC,AMD1,RCOR1,KIF11,NDRG3,PATL1,CAND1,NAP1L1,BIRC5,HNRNPH3,TFDP1,CEBPG,PREPL,RBBP4,UBE2C,CCNB2 |
| 1.720e-19 | -43.21 | GO_PROTEIN_MODIFICATION_BY_SMALL_PROTEIN_CONJUGATION_OR_REMOVAL | MSigDB lists | GO_PROTEIN_MODIFICATION_BY_SMALL_PROTEIN_CONJUGATION_OR_REMOVAL | 848 | 227 | 17377 | 2626 |
MIB2,CCNC,UBE2E2,NUP188,DCAF15,TRIM11,XIAP,CUL1,UBE2Z,UBE2Q1,USP39,USP48,CCNB1,UBE2I,BIRC2,RNF103,FBXO22,ZER1,FANCL,PCNA,PSMD1,NUP210,CDC42,ATG3,FBXW2,JOSD1,NUP153,MARCH2,ASB6,SENP1,SEH1L,USP34,RYBP,PLK1,COPS8,SP3,TRIM8,RBX1,VHL,TOPORS,UBE2V1,AURKB,BRCA1,DCUN1D5,USP22,CCNF,CBFB,USP21,TRIM4,PAF1,RAD18,RPS27A,PSMD8,TPP2,SOCS4,COPS6,FBXL3,ARRB2,TRAF5,PSMC1,DCAF5,AAAS,WSB2,UBE2D3,CTU2,NSMCE4A,UFC1,TOP2B,ZNRF3,PSMD9,CDC73,NUP205,WDR48,DDRGK1,DTL,RNF121,UBE2Q2,SMC3,MED8,MED10,KLHL5,ZNRF2,HDAC7,PPIL2,FBXO7,CTR9,BCL2,FBXL7,UBE3C,ZRANB1,RNF135,LRSAM1,NUP85,UBE2QL1,SOCS5,DCAF8,PSMA1,USP10,NFATC2IP,UBE4B,SYVN1,PSMB3,PSMC4,CAND1,CDC27,KLHL15,SIAH2,USP32,DCAF11,PIAS2,VCPIP1,NUP62,RNF14,RNF139,CDKN2A,RNF114,USP7,TRIM41,ATXN3,CYLD,TRAF7,UBR2,SUZ12,SUMO2,PTTG1,WDTC1,KLHL18,ANKIB1,USP5,PHC2,MDM2,PSMA6,FBXL6,SP100,SIAH1,UCHL5,MTA1,UBA5,NUP107,SOCS6,TTC3,ANAPC7,FAM76B,RNF19A,SPSB3,RNF169,PRPF19,RLIM,BIRC3,PSMA8,RNF25,CUL3,PSMB7,NUP155,KIAA1586,CDC23,ASB13,PSMB9,TRIM28,USP36,BTBD1,SOCS7,CDC16,NSMCE2,PSMD3,UHRF2,RNF38,TRIM32,USP11,XRCC4,SMURF1,USP53,CBX4,ZC3HC1,USP13,OTUD5,TRIP12,KLHL21,SHPRH,RAE1,EYA1,ZFP91,BABAM1,FAM76A,NUP54,CDCA8,CDCA3,BRAP,CBLL1,SMC6,UBE4A,DCUN1D4,BLM,WWP2,FBXO3,RFWD3,HERC3,PSMD2,KLHL20,HUWE1,FEM1B,LTN1,COPS7B,UBE3B,UBE2M,RNF5,DCAF6,TNFAIP3,KAT2A,USP42,FBXO9,RFFL,ANAPC2,RANGAP1,OTUD3,PCGF1,RPA1,FBXO21,KEAP1,BIRC5,KBTBD7,PML,DTX4,USP20,UBE2C,ANAPC4,DDB1 |
| 1.807e-19 | -43.16 | GO_INTRACELLULAR_PROTEIN_TRANSPORT | MSigDB lists | GO_INTRACELLULAR_PROTEIN_TRANSPORT | 750 | 207 | 17377 | 2626 |
POLA2,RAB14,NUP188,MTX3,COPA,TSC2,SNX15,TAP1,AP3M2,BECN1,SYNRG,SSR1,RPL23A,CDK5,RAB8A,NAPG,RAP1A,SNUPN,TIMM23,ATG3,AP3S2,RABGAP1L,RAB35,RAB4A,AP1M1,AP2B1,TIMM50,CDC37,SRP72,USO1,AKT2,TLK1,NUTF2,ICMT,STX16,RAB5B,RAB22A,RAB2B,OPTN,RPL37,TRAM2,TIMM13,TMED10,RPS27A,RPS14,EIF2D,ITGB1,KPNA2,RPS26,LONP2,TBC1D12,RPS15,SEC61G,GGA1,PHB2,RAB23,NKD2,RPL15,RAB6A,XPO7,COPG2,VPS25,RHBDD1,LMNA,NUP205,NPLOC4,COPB2,ATG4A,SNX18,KIF13B,FBXO7,ARL6IP1,TNPO3,SYTL3,NUP85,TMED2,KDELR1,NAGPA,EIF5A,TIMM8B,GCC2,RPS10,RPL6,RPS24,SSR2,KRAS,RIT1,SYVN1,MTX1,TOMM40,PTTG1IP,ZDHHC3,RHOB,BBS12,RPL36,DERL1,SCARB2,GOLGA4,KPNA1,PCM1,NSF,SIL1,NUP62,CTSA,YWHAZ,TOB1,RHOG,SNX27,TOMM20,SYS1,RPLP2,RAB11B,DYNLL1,ANK3,VTI1A,TBC1D13,AP1B1,RPAIN,BCAP31,STAM,RPL11,RAB21,SAR1A,TBC1D22A,RALB,TBC1D14,NUP107,TNPO2,BCAP29,TAP2,LMAN1,AHCYL1,CLTB,F2R,GCC1,SNX8,RPL29,RPL35,SEC61B,NXT1,RAB7A,RPL38,NUP155,RAB1A,AP4E1,RPS9,RPSA,HSPA4,CHMP4A,PEX5,SEC61A1,SURF4,VPS26B,RAB24,TIMM17A,ARNTL,SEL1L,RPLP1,AP1S1,CHMP4B,FAU,SMURF1,MAPK1,AP2S1,PARD3,RPS2,RAE1,TRAK1,VPS45,NUP54,GGA2,AP3S1,IFT27,RAB11A,RPL17,SEC24C,ARHGEF2,RPL19,STAT3,IFT46,MTX2,PACS2,TGFB1,PPP3CA,SNX2,RPL8,PACS1,RAB3IP,ZP3,RPL27A,MACF1,MFN2,MAPK3,RAB18,HGS,KPNA4,PDCD6,SEC23IP,GOLGA7,RPL32,STX18,PML,SSNA1,YWHAH,VPS29,IPO4,SNAPIN |
| 2.344e-19 | -42.90 | regulation of cell cycle | biological process | GO:0051726 | 1201 | 297 | 17256 | 2622 |
HECA,FGFR1OP,MAX,PDCD6IP,TSC2,CUL1,CCNL2,CCNB1,CALM2,CDK5,CDKN2C,PA2G4,PSMD1,NEK6,ECD,CDC25B,MLST8,CDC5L,BAK1,PLK3,AATF,AKT2,EHMT1,NSUN2,MKI67,MRNIP,USP22,AURKB,CCNF,DOT1L,MAP3K4,HHEX,RPS27A,PSMD8,ITGB1,TFDP2,E2F2,SLF1,PDCD4,SLC25A33,MAPRE1,CLSPN,GADD45G,PRKAA1,KIF23,TOP2B,HAUS4,EIF2AK4,NOTCH2,PSMD9,METTL3,HAUS2,CDC73,YY1AP1,SPAG5,CNOT3,JMY,DDRGK1,TFAP4,PDXP,SMC3,INTS7,FBXO7,MSH2,FBXL7,TERF2,GTPBP4,MYBL2,SRSF5,MAP2K2,RHOB,PSMB3,DUSP3,FAM83D,CNOT6,NDE1,ZNF830,CDK2,CABLES1,CDKN2A,ZNF207,POC1A,SUZ12,PTTG1,RMI2,TPX2,BCL2L1,PRKACA,APP,CCNA2,AHCTF1,NABP1,CDKN1B,TP53BP2,CEP63,ATF2,CDK12,RPRD1B,DCTN1,PSRC1,BRD4,CDC123,INTS13,MAP4K4,TAOK1,CUL3,NUSAP1,PKMYT1,CDC23,PSMB9,RAD51C,CDC16,NSMCE2,HIPK2,H2AFX,TRIM32,GEN1,CSNK1D,TUBB,PKP4,MECP2,BABAM1,BLM,SPDL1,RAB11A,MAD2L2,RFWD3,RPA2,CCNK,PSMD2,PTEN,CENPJ,PTPN11,PRC1,AXIN2,GTSE1,FEM1B,CITED2,CNOT6L,MAP3K14,KAT2A,TNFAIP3,NEK7,TBRG4,KIF11,SH3GLB1,CBX3,TFDP1,PML,SSNA1,WDR76,TAF6,ESPL1,THAP5,ANAPC4,DDB1,CCNC,GPR132,UBE2E2,THOC1,KMT2E,CSNK2A1,SIRT2,BECN1,MAPK14,BIRC2,FANCI,PRNP,LIN9,PCNA,CDC42,CARM1,TACC3,PTPRK,CDC37,RYBP,SRPK2,PLK1,RBX1,RRM2,LRP5,CDC6,BRCA1,SOX4,ANLN,RHEB,PAF1,E2F4,PPM1G,CAB39,ZNF268,STK11,CHEK2,VPS4A,PSMC1,PHB2,CENPF,LAMTOR3,CTCF,CDK13,RACGAP1,CRLF3,CNOT11,DTL,RB1,CCP110,TIMELESS,BCL2,KNTC1,MCPH1,PSMA1,MAP4K3,EIF4G2,DAPK3,MASTL,HAUS8,PSMC4,TSC1,PCM1,CDC27,LAMTOR4,CDCA5,ODF2,NUP62,RBBP4,CCNB2,BCCIP,CHMP2A,PRKAB1,CYLD,FOXM1,DYNLL1,RRAGC,RAD23A,BABAM2,MDM2,PSMA6,KIF14,PIN1,TARDBP,CABLES2,CTDSP2,HTRA2,PRPF19,TIMP2,PGGT1B,PSMA8,BTG2,PSMB7,PCGF6,CHMP2B,RBL1,PSMD3,ARNTL,GADD45B,UHRF2,XRCC3,CHMP4B,GAS2,RAD51D,MIF,KIF3B,KLHL21,RAE1,CDT1,CDK2AP2,DCTN2,CDK11B,PAGR1,FBXO5,NABP2,BRD7,H2AFY,STAT3,TGFB1,PPP1R9B,RHOA,ADAM17,HMGN5,PRKDC,ASPM,PRMT2,MEN1,BORA,CDK11A,HSPA1B,MFN2,CNOT9,NEK1,BIRC5,E2F1,PKD2,NR2F2,UBE2C,TERF1,SLF2,HRAS |
| 2.375e-19 | -42.88 | MARSON_BOUND_BY_FOXP3_UNSTIMULATED | MSigDB lists | MARSON_BOUND_BY_FOXP3_UNSTIMULATED | 1150 | 286 | 17377 | 2626 |
PDCD6IP,TXN,ADD1,TMEM203,TSC22D3,YTHDF3,SLC20A1,PARK7,CMTM6,SLC25A37,ZNF275,USF1,RNASEK,NUP153,MOB1A,TIPARP,ORAI2,KIF15,HNRNPF,SLC17A5,AURKB,WBP1,ZFAND5,MKNK1,RBM47,KIF18B,TMED10,PSMD8,TPP2,OGT,SMG9,FBXL3,E2F2,DDX42,NXT2,HSPH1,EWSR1,KIAA0100,PHF23,C16orf87,KIF23,B4GALT1,TOP2B,HAUS4,SUPT7L,PSEN1,MYL6B,NDUFS4,FBRS,FKBP1A,FAM192A,ZNRF2,LRRC8D,OSTF1,PIK3IP1,PIKFYVE,NSUN4,PABPC1,AGGF1,ETV3,MAPKAPK3,ARID1A,MPG,MAP2K2,RHOB,PHF6,CAT,MTHFD2,CSK,DCK,MDH1,ZC3HAV1,EGLN1,CYTIP,GGNBP2,RWDD1,ACTR3,PTTG1,CREBL2,NUF2,ARL6IP6,FLAD1,APLP2,SHC1,DUT,DDA1,CDKN1B,ANKRD13C,MAPRE2,EID1,CDC123,OAF,MAP4K4,CUL3,WBP2,ATP6V0A1,TMEM147,POLG2,TAZ,AMZ2,ANKZF1,EIF3K,VEZF1,HSPA4,PPP2R5A,RPLP1,RNF38,DMWD,PPP5C,GEN1,XRCC4,OTUD5,SESTD1,MANBA,MYNN,JMJD6,AKT1S1,BLM,ETS1,FOXO3,HMG20A,CCDC28A,MAT2B,KRI1,COPS7B,UBE3B,CREB1,MAP3K14,CNOT6L,CITED2,IFT46,MSH6,TSHZ1,PPP3CA,DDX24,DENND1B,EMP3,KLF6,KIF11,PICALM,PRDX1,ECH1,POLR2A,SMAP2,SGSH,MAPK6,PML,SSNA1,PARP10,DDB1,UBL3,NAT9,LYRM4,PLXNC1,USP48,BRIX1,FANCI,MBD4,ZER1,KRR1,HADHB,EIF5,FGFR1OP2,SRPK2,TRIM8,ZBED5,GMFB,UBE2V1,ARHGDIB,PITPNB,PRPSAP1,STX16,USP21,RHEB,TBC1D17,CAB39,NGLY1,RPS26,PSMC1,POT1,FUBP1,RMND5A,C1orf74,UBE2D3,SEPHS2,UFC1,MEF2A,XPO7,RGS2,PRPF18,SUB1,NFATC3,VMP1,SSBP3,XPA,MRPL48,ACAD8,HP1BP3,ABHD2,NUDT4,NQO2,LDB1,ICAM2,ARMC8,ARHGAP15,DAPK3,CDC27,NUP62,YWHAZ,NANP,C11orf1,NIPA1,WASF2,MPHOSPH8,FAM207A,TOR1AIP1,SUMO2,PMS2,CLCC1,PCBP1,GGPS1,ZADH2,SEC11A,WDR44,MRPL34,POU2AF1,RPL29,PPT1,ATXN1,FRAT2,TOR1AIP2,DCLRE1C,EIF3H,SRSF1,PON2,SURF4,RBL1,STAT6,H3F3A,ZNF146,MCM10,CDC40,GOLPH3L,DAP,SRGN,DBF4,VPS45,ARID5A,CDK11B,CSNK1A1,BZW2,RGS1,SPPL2A,HERC3,KIF5B,PTPN2,IRF4,CTSS,SLC35B4,H2AFY,ATG13,CENPM,FBL,LDLRAD3,STAT3,FRMD8,GINS1,TGFB1,CSNK1G2,GTF3C6,ELOVL5,RHOA,MLEC,NASP,METTL5,MIER1,ARHGEF12,PPWD1,RAB18,ATP6V1D,OSBPL8,ACAT1,RBPJ,PGAM1,TERF1,IFI16 |
| 2.604e-19 | -42.79 | MORF_HAT1 | MSigDB lists | MORF_HAT1 | 165 | 73 | 17377 | 2626 |
KARS,IMMT,H2AFZ,HNRNPAB,CHERP,STARD7,CCNB1,MRPL19,PARK7,RAD23A,HNRNPA2B1,PCNA,RAD23B,TARDBP,CCT2,SNRNP200,CDC123,PSMB7,VDAC2,SLBP,DNAJC9,CDC23,VDAC1,TRIM28,SRSF1,KIF2A,HSPA4,HNRNPR,PPM1G,COX5A,BAZ1B,KPNA2,AP2S1,HDAC2,NDUFV2,NDUFS1,MRPL9,RRM1,CYCS,XPO7,AP3S1,HDDC2,SMC3,NDUFV1,AHSA1,BANF1,CAPZA1,MSH2,PTPN11,EI24,PTGES3,MAML1,HNRNPM,NUDC,IFRD1,POLR2I,NSDHL,TUFM,ILF3,EIF4H,SNRPA,TARS,RPA1,SDHB,PRDX3,RBMX,MFAP1,PRPS2,TFDP1,ACLY,MDH1,ESPL1,MRPL3 |
| 3.338e-19 | -42.54 | Cell Cycle | REACTOME pathways | R-HSA-1640170 | 621 | 189 | 10287 | 1696 |
POLA2,FGFR1OP,MAX,H2AFZ,NUP188,ENSA,CUL1,CSNK2A1,KIF2C,CCNB1,UBE2I,MIS12,LIN9,CDKN2C,RAB8A,PCNA,PSMD1,NUP210,NEK6,PDS5B,NUP153,CDC25B,SEH1L,PLK1,USO1,RBX1,AKT2,RRM2,CDC6,AURKB,BRCA1,SMC2,DIDO1,MCM2,RFC2,GINS4,OPTN,PRIM1,RPS27A,PSMD8,E2F4,CHEK2,TFDP2,E2F2,PSMC1,POT1,AAAS,MAPRE1,PPP1R12A,HJURP,CLSPN,GORASP1,CENPF,KIF23,HAUS4,PMF1,PSMD9,HAUS2,NUP205,LMNA,RB1,SMC3,CCP110,MCM5,BANF1,FBXL7,KNTC1,MCPH1,NUP85,TERF2,PRIM2,MYBL2,PSMA1,GORASP2,PSMB3,PSMC4,HAUS8,MASTL,PCM1,GOLGA2,CDC27,ODF2,CDCA5,NUP62,YWHAZ,RUVBL2,RBBP4,NDE1,CDK2,CCNB2,NUP58,CDKN2A,NDC1,FOXM1,DYNLL1,PTTG1,RMI2,TPX2,NUF2,ORC1,PRKACA,TERF2IP,OIP5,MDM2,AHCTF1,PSMA6,CCNA2,BABAM2,LPIN2,NUP107,CDKN1B,ANAPC7,CEP63,DCTN1,ANKLE2,MND1,RFC3,PSMA8,TAOK1,TUBGCP5,PSMB7,E2F3,NUP155,PKMYT1,CDC23,RAB1A,H2AFV,PSMB9,CENPU,PPP2CA,KIF2A,RAD51C,CDC16,PPP2R5A,DSN1,RBL1,PSMD3,H2AFX,H3F3A,MAPK1,PPP2R2D,TUBB,CSNK1D,MCM10,RAE1,CDT1,DCTN2,BABAM1,DBF4,NUP54,CDCA8,SPDL1,CDK11B,BLM,NCAPG,RMI1,TUBGCP2,FBXO5,RPA2,PSMD2,CENPJ,KMT5A,GTSE1,CENPM,ORC3,SMC4,NUDC,GINS1,NEK7,TOP3A,ANAPC2,RANGAP1,BORA,CDK11A,MAPK3,RPA1,LEMD2,KIF18A,POLE,BIRC5,TFDP1,E2F1,SSNA1,CENPT,UBE2C,YWHAH,TERF1,ESPL1,ANAPC4 |
| 3.455e-19 | -42.51 | pleura-mesothelioma | COSMIC cancer mutations | pleura-mesothelioma | 4243 | 815 | 17385 | 2587 |
RAB14,FGFR1OP,KDM4A,PIGQ,XIAP,DHX8,LACTB2,PPP1R16B,ZNF275,FBXO22,EEF2K,CDKN2C,CDK5,NEK6,RABGAP1L,RAD23B,SRSF4,UPRT,NUP153,RNF26,SENP1,PCBP2,MLST8,PLK3,BAK1,ERCC1,RHOBTB3,NRAS,GABPA,MCL1,TOPORS,SMC2,PPFIA3,MCM2,ICMT,RAB22A,ARF4,KRIT1,TRIM47,SMAD2,MID1IP1,WDR11,RAD18,LIMK1,AXIN1,OGT,RNASEL,FBXL3,TFDP2,SMAD1,E2F2,PDCD4,PFKP,NXT2,SSRP1,DDX42,CLSPN,RHOC,TRIO,RAB23,CERK,TOP2B,EZH1,EIF2AK4,PDCD7,ITGB5,APH1B,LMNA,MCTS1,ATG4A,DDX56,SLC38A5,RNFT1,INPP5A,MCM5,FBXO7,PHF14,FOXN2,GEMIN4,NUP85,PHKG2,SRSF11,ETV3,DHX29,MYBL2,ITM2A,USP10,BCLAF1,SRSF5,MPG,ELK1,RHOB,PTPRF,MAGED2,DTWD1,KPNA1,ETS2,DUSP3,MDH1,SNX14,RNF139,ALS2,EGLN1,RHOG,TRIM41,TRERF1,PTTG1,CHD1L,TPX2,MYH9,NUF2,PRKACA,KTN1,RAB21,PRKD3,FBXL6,DUT,UBA5,NUP107,ANAPC7,RNF19A,RBM15,ARL5A,SNX8,GOPC,IDH3A,MAP4K4,CIRBP,E2F3,MEF2D,DNAJA1,RAB1A,TAZ,FKBP3,DDX17,KIF2A,TAF2,PPP2CA,CDC16,LSM6,CORO1C,HIPK2,RNF38,FUS,PDXK,PPP5C,GEN1,USP13,SRSF6,SESTD1,SIKE1,UBE4A,IP6K2,IL21R,ETS1,IFT27,SLC25A43,NEIL2,PPP1R3B,FBXO3,RPA2,ERH,PDCD10,CLIC4,ITGB8,SUV39H2,HUWE1,PPP1R8,ARF5,ARHGEF1,GEMIN6,UBE3B,GTF2H2,FBXL19,IMPA2,LDHB,PDPK1,STAU1,PPP3CA,TK1,TNFAIP3,DDX24,POLK,LDHA,MTMR12,RAB3IP,DDX39A,PICALM,RPA1,MAGT1,POLE,CCDC6,WNT5B,PITX1,MAPK6,FAM3C,PML,AEN,HMGB2,RGL1,CD81,YWHAH,IGBP1,FAF1,ANAPC4,COX15,DDX47,WDR13,TRIM11,PPP1R15B,SNX15,CSNK2A1,GIT2,BIRC2,FANCL,ABL2,RAB8A,PCNA,NUP210,NT5DC1,IL6ST,PIK3R2,XRCC2,ETV6,MYBL1,ASB6,PTPRK,VPS13B,PLK1,SP3,PTPN18,SEPT9,RBX1,SNRPB,RAD51AP1,TLK1,GMFB,LNX2,CDC6,LRP5,UBE2V1,UTP3,BRCA1,RAB5B,USP21,RHEB,TRIM4,FBXO28,CHD3,E2F4,SOCS4,BCL7C,ADAM9,KPNA2,ACTB,DVL1,NUDT11,POT1,NUMB,FUBP1,DNAJB2,NKD2,LAMTOR3,RACGAP1,COX4I1,CDK13,ADCK5,RAB6A,DNAJB1,PPP3CB,RAPGEF6,RB1,NUS1,VMP1,MBD2,XPA,RBM3,AFF1,MAML1,CYTH1,ABHD2,TRAPPC9,NSDHL,ACSL3,LDB1,KRAS,MAP4K3,EIF2AK1,UBE4B,ICAM2,IRF5,SDHB,MBIP,CDC27,PALB2,COX7A2L,PRPS2,ZDHHC7,RUVBL2,CCNB2,USP7,SART1,TRAF7,FOXM1,XAB2,SUMO2,LAGE3,PCBP1,LYN,DUSP22,BCAP31,RAD23A,RPL11,VAV1,CSDE1,MRPL50,PDK2,PSMA6,MDM2,WDR44,PIN1,PDCD2,CORO1A,MINPP1,STRAP,SAP30L,SPSB3,DVL2,SNX25,KDM3B,ARHGAP17,BIRC3,BTG2,RAB7A,DNAJC9,NUP155,DCLRE1C,CHMP2B,ARL5B,EIF3H,USP36,SRSF1,DNAJC10,DHX16,PLEKHG4B,CLK3,RBL1,STK38,MAFK,FASTK,UHRF2,DNAJC17,AP1S1,XRCC3,NCOA1,USP53,SMAD4,RAD51D,INTS2,BCL2L12,MCM10,GOLIM4,CDT1,ARID5A,SMC6,NKRF,HMGN3,ARF1,CSNK1A1,SCYL2,DNAJB9,TFRC,FZD6,PTPN2,HERC3,IRF4,ABCD1,SS18L1,DDX31,ORC3,CAMK2G,RNF5,CNTN5,RHOA,HMGN5,SNX2,TOP3A,ARHGEF12,PCGF1,DDX23,RAB18,TRIM26,KPNA4,PDCD6,FBXO41,ATP6V1D,BIRC5,TFE3,NEIL3,E2F1,PGRMC1,USP20,IMPDH1,RBPJ,NR2F2,PGAM1,RPS6KC1,UBE2C,HIPK3,NUP188,MAX,PDCD6IP,ADAM10,CXXC1,TSC22D3,USP39,CUL1,CCNB1,IKBIP,UBE2I,PARK7,RAB4A,SUCLG2,CDC25B,PLCL2,TFG,SMARCE1,DNMT1,CDC5L,ORAI2,KLF10,AKT2,PBK,GNG7,DDX20,AURKB,USP22,CCNF,CBFB,RFC2,SLC25A5,RAB2B,EIF3A,DOT1L,ZMYM3,MAP3K4,ANKRD10,HHEX,WAS,ITGB1,PTPN7,PTPDC1,TRAF5,ZMAT3,HDAC2,PTOV1,DDX58,RECQL,COX5B,DNAJC5,CHTF18,GSPT2,VAV2,PRKAA1,RRM1,KIF23,CYCS,NOTCH2,PSEN1,JMY,CFLAR,FKBP1A,RPN1,RNF121,MEX3C,SNX18,HDAC7,ATIC,PPP4R1,MSH2,DAPK1,FBXL7,CYC1,PIKFYVE,RNF135,GNAI2,ANKHD1,EEF1D,TERF2,SOCS5,PHF10,DDX28,PRIM2,PIGT,MFNG,PIP4K2C,ARID1A,RIT1,KDM3A,MAP2K2,PHF6,AKAP1,FAS,PI4K2A,XRCC5,HMGN2,ADSS,CAT,DERL1,PFDN5,TMEM54,ZFP92,RBMX,ACLY,PIAS2,USP32,PPP3R1,VCPIP1,GPI,YY1,MAP3K5,RNF14,CDK2,NRBP1,CDKN2A,DNMT3A,TP53RK,REPS2,RAB11B,TRIP10,RAF1,SUZ12,RPS6KA1,SF3B1,MAGED1,RAC1,BCL2L1,SDHA,GNB2,EPM2A,PHC2,CRKL,TERF2IP,CCNA2,ZNF75D,SHC1,KDM2A,RALB,SIAH1,LPIN2,SOCS6,CDKN1B,TNPO2,TP53BP2,CDK12,SAP30,CCT2,BRD4,MAPRE2,RFC3,HMGN4,ERF,NARF,CUL3,PKMYT1,CDC23,ASB13,POLG2,ERC1,EML4,TRIM28,DHX57,RAD51C,HSPA4,PPP2R5A,JAK1,ACYP1,SAFB,STAT1,SEL1L,FTSJ1,H2AFX,TRIM32,PDCD11,XRCC4,PRPF4B,ADAM23,RHEBL1,POLQ,OTUD5,NCOR2,MECP2,TCF3,CBLL1,BLM,POFUT1,HMG20A,FOXO3,RAB11A,HLA-A,MAD2L2,JAKMIP1,EBP,WWP2,PIP5K1C,PTEN,AHSA1,AXIN2,PTPN11,COPS7B,UBE2M,NCOA2,MSH6,SMC4,JMJD4,LONRF3,NET1,NEK7,RABIF,ADSL,FBXO9,ANAPC2,KIF11,MARK2,TSR2,FADD,CBX3,PLD3,FBXO21,GNA12,PFDN4,MFAP1,TFDP1,KHSRP,PPP1R11,DDX5,DUSP11,BRWD3,ESPL1,IPO4,GPR89B,DEF6,DDB1,RORB,POLA2,PIGM,IER2,UBE2E2,ST13,NF1,PTP4A3,UBE2Q1,AGFG1,SIRT2,KIF2C,FKBP2,USP48,UBQLN2,BECN1,MAPK14,RNF103,MBD4,RAP1A,CDC42,EIF4A3,THADA,JAZF1,RAB35,PPP1R12C,RP2,TCEA1,OGG1,ARID4A,TRIM14,SRPK2,COPS8,TRIM8,NCK1,VHL,RRM2,WDR82,PITPNB,KMT2C,SOX4,STK17B,CXXC4,GEMIN5,UEVLD,PPM1G,PQBP1,CAB39,STK11,CLU,CHEK2,COPS6,MRPL13,UBE2D3,PIGN,PPP1R2,PPP1R12A,NACA,CIB1,PCSK7,MED13L,THRAP3,RGS2,XPO7,NUP205,ZNF449,BCL2,KNTC1,UBE3C,ZRANB1,MCPH1,N4BP2,CSNK1G3,ALDH9A1,ZNF189,DAPK3,ARHGAP15,MASTL,UAP1,KLHL15,SIAH2,PITPNA,YWHAZ,NUP62,RBBP4,TOB1,SMARCD1,WASF2,MBD1,TCF12,PRKAB1,SNX27,ASH1L,MDH2,PMS2,SMARCA4,PLAGL2,ORC1,TWF2,CHD1,MXD1,USP5,SAR1A,AKAP8,PPP6C,CS,APOOL,FAM3A,SCYL3,ABI1,DNAL4,EBAG9,MOSPD1,RLIM,POU2AF1,RNF25,PCGF6,METTL2A,GLO1,OGDH,BICD2,FANCE,PDHX,RAD54B,DAP3,TAB2,TULP3,HPS5,STAT6,FKBP5,SCARB1,GAS2,USP11,SMURF1,MAPK1,PPP2R2D,CBX4,DNAJC2,CDS2,MAGEH1,SH2D3A,CASP6,RAE1,EYA1,SCYL1,DBF4,NUP54,CHIC2,MXD4,PIP4K2A,RGS1,FBXO5,FGFR3,CTNNBL1,TANK,ARHGEF2,STAT3,FRMD8,AMPD2,CSNK1G2,ADAM17,HMGN1,TFEB,MAPK3,MTMR3,COX8A,SRSF3,ZMIZ1,IDH3B,HRAS,TERF1,RAB3IL1 |
| 3.763e-19 | -42.42 | LOPEZ_MBD_TARGETS | MSigDB lists | LOPEZ_MBD_TARGETS | 888 | 234 | 17377 | 2626 |
ZNF496,MAX,ST13,PRKCSH,PPP1R15B,EBNA1BP2,UBE2I,SEC16A,CDK5,PA2G4,RAB8A,RAP1A,PCNA,CDC42,SIVA1,SRSF4,FBXW2,MAST2,TCEA1,TFG,PCBP2,CDC37,ABCC5,RBX1,APH1A,VHL,HNRNPF,RRM2,EZR,WDR82,LRP5,USP22,RHEB,ASF1B,DOT1L,RPL37,AGPAT2,PSMD8,RPS14,E2F4,ATP6V0C,PIEZO1,BTF3,TRAF5,MYL12B,CAPN1,ANXA11,FUBP1,UBE2D3,PPIB,NDUFV2,EWSR1,HLA-E,RHOC,RRM1,TOP2B,CYCS,SLC35B1,RAB6A,XPO7,ZNF79,ZNF518A,PSMD9,RSAD1,YY1AP1,COPB2,MCTS1,GNS,RNF121,RPN1,SUB1,EIF2S2,SSBP3,PPIL2,FBXO7,XPA,MEA1,FAM89B,MSH2,AHCY,GLE1,ATP6V0D1,HDHD2,EEF1D,KDELR1,ALDH9A1,IFRD1,ABHD2,TRAPPC9,CREG1,NQO2,ERLIN1,MYBL2,MFNG,PSMA1,KCTD20,RPS24,EIF2A,SEPT7,CYFIP2,TOMM40,PTTG1IP,PATL1,SLTM,PSMB3,RHOB,PSMC4,XRCC5,HMGN2,PTPRF,SCARB2,NAP1L1,KPNA1,FNTA,NSF,DUSP3,TCOF1,RBBP4,CDK2,CCNB2,SMARCD1,RPS6KA1,RAF1,PTTG1,SLC2A1,UCK2,DAZAP2,STMN1,RPAIN,APP,MEAF6,RPL11,USP5,APLP2,ATP6V0B,PDK2,ZNF75D,SHC1,IARS,DUT,MRPS27,PPP6C,CORO1A,TP53BP2,FAM3A,CFL1,ATP6V1G1,ADCY7,PPIF,RFC3,SEC61B,BIRC3,HMGN4,DRAP1,SELPLG,PPIE,PSMB7,WIPF1,GLO1,RAB1A,PSMB9,MAT2A,EIF3H,NSA2,EIF3K,ALDH3B1,CHMP4A,SEC61A1,FASTK,GADD45B,PPA2,FTSJ1,RPS2,ZFP91,CDK2AP2,AGPAT3,SIKE1,AKT1S1,MXD4,AP3S1,FGFR3,NDUFV1,ADD3,PDCD10,DNAJC8,COQ4,HUWE1,CRAT,PTPN11,BTF3L4,ANXA5,ARHGEF2,ABCD1,NDUFS8,PTGES3,OSTC,SGCB,UBE2M,MED22,SPTAN1,PPP3CA,RHOA,NEK7,WDR18,MIER1,ILF3,LDHA,ADSL,RABIF,RANGAP1,PACS1,MEN1,KIF11,PICALM,CDK11A,ECH1,PRDX1,MAPK3,DDX23,HLA-B,TPD52L2,SLC19A1,UPF1,BIRC5,CCDC6,MFAP1,WNT5B,TFDP1,COX8A,IMPDH1,USP20,SSNA1,UBE2C,DDB1 |
| 4.075e-19 | -42.34 | organelle envelope | cellular component | GO:0031967 | 1143 | 280 | 18223 | 2701 |
NUP188,NDUFB6,MRPS15,TMEM109,UBE2I,PARK7,SLC25A37,SNUPN,DNM2,TRA2B,NUP153,CISD2,LRRC59,SENP1,SEH1L,MRPL57,BAK1,MRPL43,MCL1,NUTF2,COA7,SLC25A5,FOXRED1,STOML2,RPS27A,MRPL27,MPV17,COX5A,UQCRH,SMAD1,AAAS,ANXA11,SLC25A33,NXT2,NDUFV2,COX5B,MRPL9,MRPS2,RRM1,NDUFA4,CYCS,PSEN1,NDUFS7,LMNA,NDUFS4,NDUFAF6,BDH1,SLC25A51,RTCB,TNPO3,MRPL40,CYC1,MRPL21,MVP,TNRC18,NUP85,EIF5A,TIMM8B,SIGMAR1,COQ8A,RB1CC1,NOA1,PGS1,GTPBP4,MRPL16,MTX1,TOMM40,SFXN5,ABCF1,MATR3,CYB5A,AKAP1,CAT,KPNA1,MRPL3,NUP58,NDC1,ATXN3,RAF1,STARD7,TMEM97,BCL2L1,SLC25A44,SNN,SDHA,APP,TERF2IP,MOAP1,AHCTF1,UTP18,MTA1,NUP107,MRPS27,MICU2,TNPO2,MAVS,RBM15,ATF2,DCTN1,CPNE1,VDAC2,HTATIP2,NDUFA7,TAZ,CHCHD3,ANKZF1,MRPL55,CERS6,ATF6,TUBB,NDUFS1,SLC25A12,BRAP,GMCL1,AGPAT3,ATP5F1B,SLC25A43,FOXO3,SLC25A36,EBP,NDUFA2,COQ4,NDUFB4,CRAT,MRPL54,NDUFA3,MTX2,S100A6,TMEM126B,MRS2,MRPS10,RHOT1,GUF1,SH3GLB1,CBX3,ATP5MC3,LRPPRC,AEN,SLC25A19,NDUFS5,HIGD2A,IPO4,FAF1,COX15,MTX3,UQCR10,ABCB10,AGFG1,BECN1,ATP5PF,MRPL19,PRNP,FANCL,DST,NUP210,GOT2,TIMM23,INTS1,SLC44A1,HADHB,NDUFB9,TRIM14,MRPL32,TIMM50,MRPL12,SLC25A22,MPC1,TIMM13,TIMM29,NRM,KPNA2,DHFR2,CLU,MRPL13,NEMP2,PHB2,DNAJB2,CENPF,CHCHD2,COX4I1,XPO7,QSOX2,NUP205,DTL,MLX,TIGAR,BANF1,EI24,YBX1,BCL2,MRPL48,GLE1,ALDH18A1,ATP5IF1,ACSL3,NPIPA1,SDHB,PCM1,NSMF,COX7A2L,NUP62,ATP5F1A,TMEM14A,NIPSNAP2,CHMP2A,NDUFA5,IMMT,TOMM20,NDUFAF2,MRPL39,TOR1AIP1,LYN,MIEF1,MRPL50,ANKLE1,MRPL34,PARL,APOOL,TMEM14C,HTRA2,PPIF,ACSL5,NXT1,COQ10B,CPOX,DMAC2,MTMR6,NLN,NUP155,TOR1AIP2,ERBIN,OGDH,BICD2,VDAC1,NDUFB1,MRPS14,TXNL4A,GFER,TMEM201,MRPL2,DAP3,TIMM17A,CHCHD1,TOMM6,STAT6,NDUFA11,CHMP4B,SLC25A39,ZC3HC1,TMEM33,INTS2,DNAJC2,CDS2,MRPL42,RAE1,NUP54,MRPS26,LETMD1,TIMM21,NDUFV1,NDUFS8,MRPL11,STAT3,RNF5,SLC25A1,COA3,TIMMDC1,ABCF2,RANGAP1,ATP5MF,RHOT2,CHCHD6,MFN2,MAPK3,LEMD2,KPNA4,OSBPL8,COX8A,ACADM,CHMP7 |
| 4.075e-19 | -42.34 | envelope | cellular component | GO:0031975 | 1143 | 280 | 18223 | 2701 |
NUP188,NDUFB6,MRPS15,TMEM109,UBE2I,PARK7,SLC25A37,SNUPN,DNM2,TRA2B,NUP153,CISD2,LRRC59,SENP1,SEH1L,MRPL57,BAK1,MRPL43,MCL1,NUTF2,COA7,SLC25A5,FOXRED1,STOML2,RPS27A,MRPL27,MPV17,COX5A,UQCRH,SMAD1,AAAS,ANXA11,SLC25A33,NXT2,NDUFV2,COX5B,MRPL9,MRPS2,RRM1,NDUFA4,CYCS,PSEN1,NDUFS7,LMNA,NDUFS4,NDUFAF6,BDH1,SLC25A51,RTCB,TNPO3,MRPL40,CYC1,MRPL21,MVP,TNRC18,NUP85,EIF5A,TIMM8B,SIGMAR1,COQ8A,RB1CC1,NOA1,PGS1,GTPBP4,MRPL16,MTX1,TOMM40,SFXN5,ABCF1,MATR3,CYB5A,AKAP1,CAT,KPNA1,NUP58,MRPL3,NDC1,ATXN3,RAF1,STARD7,TMEM97,BCL2L1,SLC25A44,SNN,SDHA,APP,TERF2IP,MOAP1,AHCTF1,UTP18,MTA1,NUP107,MRPS27,MICU2,TNPO2,MAVS,RBM15,ATF2,DCTN1,CPNE1,VDAC2,HTATIP2,NDUFA7,TAZ,CHCHD3,ANKZF1,MRPL55,CERS6,ATF6,TUBB,NDUFS1,SLC25A12,BRAP,GMCL1,AGPAT3,ATP5F1B,SLC25A43,FOXO3,SLC25A36,EBP,NDUFA2,COQ4,NDUFB4,CRAT,MRPL54,NDUFA3,MTX2,S100A6,TMEM126B,MRS2,MRPS10,RHOT1,GUF1,SH3GLB1,CBX3,ATP5MC3,LRPPRC,AEN,SLC25A19,NDUFS5,HIGD2A,IPO4,FAF1,COX15,MTX3,UQCR10,ABCB10,AGFG1,BECN1,ATP5PF,MRPL19,PRNP,FANCL,DST,NUP210,GOT2,TIMM23,INTS1,SLC44A1,HADHB,NDUFB9,TRIM14,MRPL32,TIMM50,MRPL12,SLC25A22,MPC1,TIMM13,TIMM29,NRM,KPNA2,DHFR2,CLU,MRPL13,NEMP2,PHB2,DNAJB2,CENPF,CHCHD2,COX4I1,XPO7,QSOX2,NUP205,DTL,MLX,TIGAR,BANF1,EI24,YBX1,BCL2,MRPL48,GLE1,ALDH18A1,ATP5IF1,ACSL3,NPIPA1,SDHB,PCM1,NSMF,COX7A2L,NUP62,ATP5F1A,TMEM14A,NIPSNAP2,CHMP2A,NDUFA5,IMMT,TOMM20,NDUFAF2,MRPL39,TOR1AIP1,LYN,MIEF1,MRPL50,ANKLE1,MRPL34,PARL,APOOL,TMEM14C,HTRA2,PPIF,ACSL5,NXT1,COQ10B,CPOX,DMAC2,MTMR6,NLN,NUP155,TOR1AIP2,ERBIN,OGDH,BICD2,VDAC1,NDUFB1,MRPS14,TXNL4A,GFER,TMEM201,MRPL2,DAP3,TIMM17A,CHCHD1,TOMM6,STAT6,NDUFA11,CHMP4B,SLC25A39,ZC3HC1,TMEM33,INTS2,DNAJC2,CDS2,MRPL42,RAE1,NUP54,MRPS26,LETMD1,TIMM21,NDUFV1,NDUFS8,MRPL11,STAT3,RNF5,SLC25A1,COA3,TIMMDC1,ABCF2,RANGAP1,ATP5MF,RHOT2,CHCHD6,MFN2,MAPK3,LEMD2,KPNA4,OSBPL8,COX8A,ACADM,CHMP7 |
| 4.516e-19 | -42.24 | BUYTAERT_PHOTODYNAMIC_THERAPY_STRESS_DN | MSigDB lists | BUYTAERT_PHOTODYNAMIC_THERAPY_STRESS_DN | 583 | 171 | 17377 | 2626 |
POLA2,ADAM10,UQCR10,CXXC1,RBM8A,TMEM109,AP3M2,AGPAT1,ENSA,UBQLN2,MAPK14,ABHD14A,POLR3K,PCYOX1L,KIFC1,CDK5,FANCL,CDKN2C,DNAAF2,PHTF1,SLC26A2,SPTSSA,PLCL2,TRIM14,PGAP2,DEAF1,RHOBTB3,PTPN18,SLC16A7,MKI67,KIF15,RRM2,ARHGDIB,AURKB,UTP3,ICMT,CCNF,GINS4,PRIM1,ZMYM3,UBTF,HHEX,TRAM2,CDCA4,KIF18B,BCL7C,GALNT10,RRS1,CHPF2,PIGN,HJURP,ADO,SDC2,PXMP2,RSAD1,CFLAR,FAM192A,SNRNP25,TNS3,SUB1,BDH1,XPA,BCL2,OSTF1,MDFIC,GEMIN4,MRPL40,VOPP1,TIMM8B,POLR2I,ERLIN1,DCAF8,AMD1,ADRB2,SEPT7,C9orf40,ZDHHC3,ZNF174,ISG15,CYB5A,PRMT7,MAP3K5,PDLIM5,TMEM14A,PTDSS1,CKLF,IVNS1ABP,MDH2,TMX4,LAGE3,ORC1,BCL2L1,HCFC1R1,FARSA,CCNA2,ATP2A2,CD3EAP,DUT,MRPL34,TARDBP,CORO1A,CLTB,CLN6,ARL5A,GM2A,EBAG9,CSTF1,ACSL5,PSRC1,ERMP1,RFC3,POLR2L,EID1,BOLA1,NDUFA7,CADM1,PSMB9,MRPS14,EML4,MAT2A,RAD54B,PON2,RAD51C,WDR7,H2AFX,AP1S1,LRP8,PPP2R2D,TUBB,USP13,NCOR2,MCM10,PKP4,C1orf112,MECP2,TOR3A,SRGN,DBF4,CDCA3,SLC25A12,LANCL1,FAM8A1,HDDC2,SAC3D1,FBXO5,EBP,GATC,FJX1,GEMIN6,ANP32A,FEM1B,COPS7B,CNN2,TTLL12,NDUFA3,TMX1,MED22,TMEM160,TTPAL,NASP,RABIF,FBXO9,TTLL4,BIRC5,NEIL3,PITX1,DBI,PGRMC1,E2F1,WDR76,SSSCA1 |
| 5.225e-19 | -42.10 | TP53 (tumor protein p53) | protein interactions | 7157 | 1047 | 279 | 17029 | 2761 |
TXN,CXXC1,TSC22D3,USP39,UBE2I,PARK7,RPL23A,CDK5,CDKN2C,RAB4A,TAF5L,ECD,DNMT1,SENP1,PLK3,BAK1,USO1,PBK,EHMT1,HNRNPF,MCL1,TOPORS,AURKB,SLC25A5,PRIM1,DOT1L,SMAD2,RPS27A,RPS14,AXIN1,RNASEL,SMAD1,HDAC2,EWSR1,MRPS2,KCTD17,TOP2B,HAUS4,SUPT7L,LMNA,WDR48,CFLAR,TFAP4,EIF2S2,EXOSC7,DAPK1,MSH2,MVP,PHKG2,PABPC1,PPA1,FOXK1,RB1CC1,PRRC2A,MTA2,ZMYND11,RPS10,GTPBP4,USP10,RPS24,ARID1A,PTTG1IP,CCT8,PSMB3,MAGED2,ETS2,PPP3R1,PIAS2,MDH1,YY1,CDK2,CABLES1,CDKN2A,TP53RK,ATXN3,NQO1,PTTG1,MYH9,BCL2L1,SAFB2,GNB2,ZNF420,CCNA2,MTA1,MRPS27,NABP1,TP53BP2,CCT2,RFC3,KAT7,DNAJA1,TRIM28,FKBP3,PPP2CA,KIF2A,HSPA4,SAFB,CORO1C,HIPK2,RNF38,H2AFX,TRIM32,TUBB,CSNK1D,OTUD5,RPS2,SRSF6,HABP4,WDR5,BLM,ETS1,FOXO3,RFWD3,RPA2,ERH,PTEN,HUWE1,RPL19,CREB1,UBE2M,NCOA2,S100A6,MSH6,MED22,HNRNPM,MFSD12,PPP3CA,TK1,TNFAIP3,KAT2A,USP42,RPL8,KLF6,RPA1,FBXO21,ZHX1,GPS2,TFDP1,PML,LRPPRC,HMGB2,DDX5,TAF6,DDB1,KMT2E,MOGS,UBE2Q1,CSNK2A1,EBNA1BP2,SNRPD3,UBQLN2,MAPK14,BECN1,MAP1LC3B,TRIM65,SF3B2,PCNA,CDC42,SIVA1,NOC2L,HADHB,CARM1,CCAR1,TIMM50,RYBP,SP3,COPS8,PLK1,ZCCHC10,TRIM8,RBX1,LAP3,VHL,RRM2,WDR82,BRCA1,SOX4,PRKRA,USP21,CHD3,MIA2,ACTB,KPNA2,STK11,CHEK2,COPS6,RPS26,NUMB,CAPN1,RPS15,PPP1R12A,RPL15,DNAJB1,THRAP3,DTL,RB1,VASP,MED8,YBX1,RBM3,BCL2,RPL6,SYVN1,UBE4B,APPL1,DAPK3,NMT2,NAP1L1,TBPL1,YWHAZ,ATP5F1A,RBBP4,MZT2B,SMARCD1,USP7,SART1,CYLD,RPLP2,MRPL39,SMARCA4,PCBP1,LYN,RAD23A,RPL11,HNRNPA2B1,BABAM2,MDM2,ZNF302,ABRAXAS2,PIN1,CABLES2,CLTB,TOP1MT,DVL2,RAB7A,CYP20A1,TOR1AIP2,DCLRE1C,MRPS14,RPS9,SRSF1,CLK3,MAFK,STAT6,CEP55,UHRF2,CHMP4B,NCOA1,USP11,FAU,SMURF1,MAPK1,MIF,BCL2L12,RAE1,AGO2,CSNK1A1,TFRC,KMT5A,NABP2,BRD7,FBL,RPRD1A,ASPM,PRKDC,RFFL,MEN1,MAPK3,HSPA1B,PDCD6,KPNA4,NEIL3,E2F1,RBPJ,ZMIZ1,IDH3B,HRAS,HIPK3,IFI16 |
| 5.409e-19 | -42.06 | cellular macromolecule catabolic process | biological process | GO:0044265 | 866 | 230 | 17256 | 2622 |
PDCD6IP,RBM8A,CUL1,UBE2Z,NHLRC3,SIRT2,SND1,UBQLN2,CCNB1,UBE2I,USP48,BIRC2,RNF103,FBXO22,PABPC4,EDC3,RPL23A,PCYOX1L,PSMD1,EIF4A3,METTL14,RAD23B,AP2B1,PCBP2,USP34,PLK1,EXOSC6,RBX1,TOPORS,USP22,AURKB,CCNF,USP21,RPL37,RPS27A,PSMD8,RPS14,AXIN1,ATE1,ARRDC1,CHEK2,VPS4A,KLHL42,SMG9,FBXL3,ARRB2,NGLY1,RPS26,PSMC1,LONP2,UBE2D3,RMND5A,RPS15,TMUB1,UBXN1,GSPT2,TATDN3,KCTD17,RPL15,THRAP3,ZNRF3,PSMD9,CNOT11,PARN,METTL3,VPS25,RHBDD1,PRPF18,CNOT3,NPLOC4,DTL,RNF121,EXOSC7,ZNRF2,FBXO7,FBXL7,ZRANB1,PABPC1,ERLIN1,MAN1B1,RPL6,RPS10,USP10,RPS24,PSMA1,EXOSC9,UBE4B,SYVN1,ARMC8,PATL1,PSMB3,ISG15,PSMC4,RPL36,DERL1,KPNA1,CDC27,KLHL15,SIAH2,DCAF11,USP32,CNOT6,CTSA,ECPAS,RNF139,USP7,ATXN3,CYLD,RPLP2,UBR2,PTTG1,PAIP1,RPL11,RAD23A,USP5,CSDE1,UBXN2A,PSMA6,MDM2,SIAH1,MTA1,KIF14,UCHL5,EXOSC1,SOCS6,NSFL1C,ANAPC7,TTC3,RNASEH2A,CLN6,SPSB3,HTRA2,RLIM,PRPF19,RPL29,SEC61B,RPL35,POLR2G,PPT1,PSMA8,RAB7A,PSMB7,CUL3,RNPS1,POLR2D,RPL38,EDEM2,CDC23,PSMB9,TOLLIP,RPS9,USP36,BTBD1,RPSA,PPP2CA,ANKZF1,DNAJC10,CDC16,IDE,LSM6,UBXN2B,PSMD3,NT5C3B,ARNTL,RNF38,SEL1L,RPLP1,CHMP4B,TRIM32,USP11,SMURF1,AP2S1,USP13,RPS2,TRIP12,MANBA,SDF2L1,UBE4A,CSNK1A1,DNAJB9,TUT4,WWP2,CAPN2,PSMD2,CTSS,KLHL20,RPL17,PPP1R8,PELO,DCP1A,GTSE1,LTN1,RPL19,UPF2,CNOT6L,FBXL19,RNF5,SAMD4B,TNFAIP3,RNASEH2C,TRIR,USP42,RPL8,RFFL,FBXO9,ANAPC2,WDR81,RPL27A,HSPA1B,CNOT9,CTSL,FBXO21,SGSH,KEAP1,UPF1,RPL32,PLAA,TATDN2,PML,KHSRP,USP20,PPP1R11,HMGB2,DDX5,TATDN1,WDR91,UBE2C,ANAPC4,DDB1,FAF1 |
| 6.816e-19 | -41.83 | mesothelioma | COSMIC cancer mutations | mesothelioma | 4538 | 861 | 17385 | 2587 |
RAB14,FGFR1OP,KDM4A,PIGQ,XIAP,DHX8,LACTB2,PPP1R16B,ZNF275,FBXO22,EEF2K,CDKN2C,CDK5,NEK6,THAP4,RABGAP1L,RAD23B,SRSF4,MECR,UPRT,NUP153,RNF26,SENP1,PCBP2,MLST8,PLK3,BAK1,ERCC1,RHOBTB3,NRAS,GABPA,MCL1,TOPORS,SMC2,PPFIA3,MCM2,ICMT,RAB22A,ARF4,KRIT1,PWWP2B,TRIM47,AHNAK,SMAD2,MID1IP1,WDR11,RAD18,LIMK1,AXIN1,OGT,RNASEL,FBXL3,TFDP2,SMAD1,E2F2,PDCD4,PFKP,NXT2,SSRP1,DDX42,HIVEP3,CLSPN,RHOC,TRIO,RAB23,CERK,TOP2B,HAUS4,ZNRF3,EZH1,EIF2AK4,PDCD7,ITGB5,APH1B,LMNA,MCTS1,ATG4A,DDX56,SLC38A5,RNFT1,INPP5A,MCM5,FBXO7,PHF14,FOXN2,GEMIN4,NUP85,PHKG2,SRSF11,ETV3,DHX29,MYBL2,ITM2A,USP10,BCLAF1,SRSF5,MPG,ELK1,RHOB,PTPRF,MAGED2,DTWD1,KPNA1,ETS2,DUSP3,MDH1,SNX14,RNF139,ALS2,EGLN1,RHOG,TRIM41,TRERF1,UBR2,PTTG1,CHD1L,TPX2,MYH9,NUF2,PRKACA,KTN1,RAB21,PRKD3,FBXL6,DUT,UBA5,NUP107,ANAPC7,RNF19A,RBM15,RPRD1B,ARL5A,PDCL3,SNX8,GOPC,IDH3A,MAP4K4,CIRBP,E2F3,MEF2D,DNAJA1,RAB1A,TAZ,FKBP3,DDX17,KIF2A,TAF2,PPP2CA,CDC16,LSM6,CORO1C,HIPK2,RNF38,FUS,PDXK,PPP5C,GEN1,ZBTB11,USP13,SRSF6,SESTD1,SIKE1,UBE4A,IP6K2,IL21R,ETS1,IFT27,SLC25A43,NEIL2,PPP1R3B,FBXO3,RPA2,ERH,PDCD10,CLIC4,ITGB8,SUV39H2,HUWE1,PPP1R8,ARF5,ARHGEF1,GEMIN6,UBE3B,GTF2H2,FBXL19,IMPA2,LDHB,PDPK1,STAU1,PPP3CA,TK1,TNFAIP3,DDX24,POLK,LDHA,MTMR12,RAB3IP,DDX39A,TTC33,PICALM,RPA1,MAGT1,POLE,CCDC6,WNT5B,PITX1,MAPK6,FAM3C,PML,AEN,HMGB2,RGL1,CD81,YWHAH,IGBP1,FAF1,ANAPC4,COX15,DDX47,WDR13,TRIM11,PPP1R15B,YTHDC2,SNX15,CSNK2A1,GIT2,BIRC2,FANCL,ABL2,RAB8A,PCNA,NUP210,NT5DC1,IL6ST,PIK3R2,XRCC2,ETV6,MYBL1,ASB6,PTPRK,VPS13B,PLK1,SP3,PTPN18,SEPT9,RBX1,APH1A,SNRPB,RAD51AP1,TLK1,GMFB,LNX2,CDC6,LRP5,UBE2V1,UTP3,BRCA1,RAB5B,USP21,RHEB,TRIM4,FBXO28,CHD3,E2F4,SOCS4,BCL7C,ADAM9,KPNA2,ACTB,DVL1,NUDT11,POT1,NUMB,FUBP1,DNAJB2,NKD2,LAMTOR3,RACGAP1,COX4I1,ADCK5,CDK13,RAB6A,DNAJB1,PPP3CB,RAPGEF6,RB1,NUS1,VMP1,MBD2,XPA,RBM3,AFF1,MAML1,PREB,CYTH1,ABHD2,TRAPPC9,NSDHL,ACSL3,LDB1,KRAS,MAP4K3,EIF2AK1,UBE4B,ICAM2,IRF5,SDHB,MBIP,PCM1,CDC27,PALB2,COX7A2L,PRPS2,ZDHHC7,RUVBL2,CCNB2,USP7,SART1,TRAF7,ARID2,FOXM1,XAB2,SUMO2,LAGE3,PCBP1,LYN,DUSP22,BCAP31,RAD23A,RPL11,VAV1,CSDE1,MRPL50,PDK2,PSMA6,MDM2,WDR44,PIN1,PDCD2,CORO1A,MINPP1,STRAP,SAP30L,SPSB3,DVL2,SNX25,KDM3B,ARHGAP17,BIRC3,BTG2,RAB7A,DNAJC9,NUP155,DCLRE1C,CHMP2B,ARL5B,EIF3H,USP36,SRSF1,DNAJC10,DHX16,PLEKHG4B,CLK3,RBL1,STK38,MAFK,FASTK,UHRF2,DNAJC17,AP1S1,XRCC3,NCOA1,USP53,SMAD4,RAD51D,INTS2,BCL2L12,MCM10,GOLIM4,CDT1,ARID5A,SMC6,NKRF,HMGN3,ARF1,CSNK1A1,SCYL2,DNAJB9,TFRC,FZD6,PTPN2,HERC3,IRF4,CTSS,ABCD1,SS18L1,DDX31,ORC3,CAMK2G,RNF5,CNTN5,RHOA,HMGN5,SNX2,TOP3A,ARHGEF12,PCGF1,DDX23,RAB18,TRIM26,KPNA4,PDCD6,FBXO41,ATP6V1D,BIRC5,TFE3,NEIL3,E2F1,PGRMC1,USP20,IMPDH1,PKD2,RBPJ,NR2F2,PGAM1,RPS6KC1,UBE2C,HIPK3,NUP188,MAX,PDCD6IP,ADAM10,CXXC1,TSC22D3,USP39,CUL1,CCNB1,IKBIP,UBE2I,PARK7,ZNF428,RAB4A,SUCLG2,CDC25B,PLCL2,TFG,SMARCE1,DNMT1,CDC5L,ORAI2,KLF10,AKT2,PBK,NOL8,GNG7,DDX20,AURKB,USP22,CCNF,CBFB,RFC2,SLC25A5,RAB2B,EIF3A,DOT1L,ZMYM3,MAP3K4,ANKRD10,HHEX,WAS,WDR4,ITGB1,PTPN7,PTPDC1,TRAF5,ZMAT3,HDAC2,PTOV1,DDX58,RECQL,COX5B,DNAJC5,EWSR1,CHTF18,GSPT2,VAV2,PRKAA1,C16orf87,RRM1,KIF23,CYCS,NOTCH2,PSEN1,JMY,CFLAR,FKBP1A,RPN1,RNF121,MEX3C,SNX18,HDAC7,ATIC,PPP4R1,MSH2,DAPK1,FBXL7,CYC1,PIKFYVE,RNF135,GNAI2,ANKHD1,EEF1D,TERF2,SOCS5,PHF10,DDX28,PRIM2,PIGT,MFNG,PIP4K2C,ARID1A,RIT1,KDM3A,MAP2K2,PHF6,AKAP1,FAS,PI4K2A,XRCC5,HMGN2,ADSS,CAT,DERL1,PFDN5,GOLGA2,TMEM54,ZFP92,RBMX,ACLY,PIAS2,USP32,PPP3R1,VCPIP1,GPI,YY1,MAP3K5,RNF14,CDK2,NRBP1,CDKN2A,ZC3HAV1,DNMT3A,TP53RK,REPS2,RAB11B,TRIP10,RAF1,SUZ12,RPS6KA1,SF3B1,MAGED1,RAC1,BCL2L1,SDHA,GNB2,EPM2A,PHC2,CRKL,TERF2IP,CCNA2,ZNF75D,SHC1,KDM2A,RALB,SIAH1,LPIN2,SOCS6,CDKN1B,TNPO2,TP53BP2,RBM12B,CDK12,SAP30,CCT2,BRD4,MAPRE2,RFC3,HMGN4,ERF,NARF,CUL3,ABHD11,PKMYT1,CDC23,ASB13,POLG2,ERC1,EML4,TRIM28,DHX57,NSA2,RAD51C,HSPA4,PPP2R5A,JAK1,ACYP1,SAFB,STAT1,SEL1L,FTSJ1,H2AFX,TRIM32,PDCD11,XRCC4,PRPF4B,ADAM23,RHEBL1,POLQ,OTUD5,NCOR2,MECP2,TCF3,CBLL1,BLM,POFUT1,HMG20A,FOXO3,RAB11A,HLA-A,MAD2L2,JAKMIP1,EBP,WWP2,PIP5K1C,PTEN,AHSA1,AXIN2,PTPN11,COPS7B,UBE2M,NCOA2,MSH6,SMC4,JMJD4,LONRF3,NET1,NEK7,RABIF,ADSL,FBXO9,BMS1,ANAPC2,KIF11,MARK2,TSR2,FADD,CBX3,PLD3,FBXO21,GNA12,PFDN4,MFAP1,TFDP1,KHSRP,PPP1R11,DDX5,DUSP11,BRWD3,ESPL1,DDB1,GPR89B,IPO4,FAM83G,DEF6,RORB,POLA2,PIGM,IER2,UBE2E2,GPR132,ST13,NF1,PTP4A3,UBE2Q1,AGFG1,SIRT2,KIF2C,FKBP2,USP48,UBQLN2,BECN1,MAPK14,RNF103,MBD4,DST,RAP1A,CDC42,EIF4A3,THADA,JAZF1,RAB35,PPP1R12C,KIF22,RP2,TCEA1,OGG1,ARID4A,TRIM14,CARM1,SRPK2,COPS8,TRIM8,NCK1,VHL,RRM2,WDR82,PITPNB,KMT2C,SOX4,STK17B,CXXC4,GEMIN5,UEVLD,PPM1G,PQBP1,CAB39,STK11,CLU,CHEK2,COPS6,MRPL13,DCAF5,UBE2D3,PIGN,PPP1R2,PPP1R12A,NACA,CIB1,PCSK7,MED13L,THRAP3,RGS2,XPO7,NUP205,ZNF449,BCL2,KNTC1,UBE3C,ZRANB1,MCPH1,N4BP2,CSNK1G3,ALDH9A1,ZNF189,DAPK3,ARHGAP15,MASTL,GNAS,UAP1,KLHL15,SIAH2,PITPNA,YWHAZ,NUP62,RBBP4,TOB1,SMARCD1,MBD1,TCF12,WASF2,PRKAB1,SNX27,ASH1L,MDH2,PMS2,SMARCA4,PLAGL2,ORC1,TWF2,CHD1,MXD1,USP5,ANKRD28,SAR1A,NVL,AKAP8,PPP6C,CS,APOOL,FAM3A,SCYL3,ABI1,DNAL4,EBAG9,MOSPD1,RLIM,POU2AF1,RNF25,PCGF6,METTL2A,ATXN1,GLO1,OGDH,BICD2,FANCE,PDHX,RAD54B,DAP3,TAB2,TULP3,HPS5,STAT6,CANT1,FKBP5,SCARB1,GAS2,USP11,SMURF1,MAPK1,PPP2R2D,CBX4,DNAJC2,CDS2,MAGEH1,SH2D3A,CASP6,RAE1,EYA1,SCYL1,NUP54,DBF4,CHIC2,MXD4,PIP4K2A,RGS1,MAN1A1,FBXO5,FGFR3,CTNNBL1,SEC24C,TANK,ARHGEF2,STAT3,FRMD8,MYO5A,AMPD2,CSNK1G2,ADAM17,HMGN1,SCFD2,PRMT2,TFEB,MAPK3,MTMR3,COX8A,SRSF3,ZMIZ1,IDH3B,TERF1,HRAS,RAB3IL1 |
| 8.410e-19 | -41.62 | ribonucleoprotein complex biogenesis | biological process | GO:0022613 | 464 | 145 | 17256 | 2622 |
DDX47,NOP2,USP39,EBNA1BP2,SNRPD3,BRIX1,EDC3,RPL23A,KRR1,UTP25,PA2G4,SNUPN,NOL11,EIF4A3,ZNHIT6,NOC2L,RPF2,KHDC4,EIF5,FTSJ3,SRPK2,SRSF10,RPP25,SNRNP200,EXOSC6,AATF,SNRPB,NOL8,RIOX2,DDX20,UTP3,LUC7L,MAK16,LSG1,CLNS1A,EIF3A,RPL37,GEMIN5,NIP7,RPS27A,RPS14,LUC7L3,EIF2D,ATXN2L,RNASEL,RRS1,RPS26,NMD3,GEMIN7,RPS15,DHX9,RPL15,PRPF39,CDC73,PRPF18,MCTS1,LYAR,DDX56,EXOSC7,GEMIN4,MRM3,NSUN4,LUC7L2,DDX28,NOA1,TEX10,RPL6,GTPBP4,UTP15,RPS10,RPS24,EXOSC9,EIF2A,SRSF5,EIF4H,PATL1,SF3A2,RPL36,TSC1,RBMX,PRMT7,RUVBL2,SART1,RPLP2,SF3B1,XAB2,URB2,EIF3D,EFL1,RPL11,RRN3,NVL,UTP18,EXOSC1,UTP4,STRAP,PRPF19,MRM2,RPL29,RPL35,CIRBP,POLR2D,RPL38,CRNKL1,PRPF3,GAR1,TXNL4A,RPS9,RPSA,SRSF1,DDX17,NSA2,LSM6,TBL3,RPLP1,SNRPG,PDCD11,CSNK1D,RPS2,RRP15,SRSF6,AGO2,GTF3A,PNO1,RRP36,KRI1,RPL17,GEMIN6,RPL19,DDX31,PTGES3,FBL,MRPL11,PPAN,YTHDC1,WDR18,RPL8,BMS1,RPL27A,TSR2,DDX23,UTP20,RPL32,BYSL,DDX52 |
| 1.033e-18 | -41.41 | GO_CELLULAR_MACROMOLECULE_LOCALIZATION | MSigDB lists | GO_CELLULAR_MACROMOLECULE_LOCALIZATION | 1177 | 289 | 17377 | 2626 |
RAB14,NUP188,TSC2,TAP1,AP3M2,SYNRG,MIS12,RPL23A,CDK5,NAPG,SNUPN,RABGAP1L,RAB4A,AP1M1,AP2B1,SEH1L,SRP72,USO1,NRAS,ATG9A,AKT2,TOPORS,AURKB,NUTF2,ICMT,RAB22A,RAB2B,ARF4,HHEX,TMED10,RPS27A,RPS14,EIF2D,ITGB1,LONP2,MAPRE1,GGA1,SEC61G,DHX9,RAB23,SUPT7L,VPS25,COPG2,COPB2,LMNA,NPLOC4,SPAG5,ATG4A,SNX18,FBXO7,TNPO3,PIKFYVE,NUP85,SYTL3,TMED2,TERF2,MORC3,NAGPA,EIF5A,TIMM8B,GCC2,RPS10,SSR2,RPS24,MTX1,RIT1,TOMM40,PTTG1IP,RHOB,DERL1,SCARB2,FNTA,KPNA1,NSF,FAM83D,WIPI2,EXOC3,RHOG,SYS1,RAB11B,ANK3,RAC1,VTI1A,TBC1D13,AP1B1,STAM,MOAP1,TERF2IP,RAB21,RALB,TBC1D22A,TBC1D14,NUP107,TNPO2,ANKRD13C,TAP2,GCC1,SNX8,SEC61B,GOPC,RPL38,DNAJA1,RAB1A,AP4E1,CHMP4A,PEX5,HSPA4,SEC61A1,RAB24,CCDC14,VPS26B,RPLP1,SEL1L,CSNK1D,RPS2,MZT1,TRAK1,FLOT1,IFT27,RAB11A,WRB,RPL17,AXIN2,DCP1A,RPL19,MTX2,IFT46,PACS2,PPP3CA,TNFAIP3,DENND4C,RPL8,PACS1,RAB3IP,ZP3,RPL27A,MACF1,SH3GLB1,HGS,KEAP1,RPL32,STX18,PML,SSNA1,ASNA1,CD81,YWHAH,IPO4,FAF1,VPS29,SNAPIN,POLA2,AGRN,MTX3,COPA,SNX15,BECN1,SSR1,RAB8A,RAP1A,CDC42,TIMM23,AP3S2,ATG3,RAB35,SRI,ZFYVE27,TIMM50,PTPRK,CDC37,PLK1,MIOS,TLK1,EZR,RAB5B,STX16,OPTN,RPL37,PAF1,TRAM2,TIMM13,TONSL,KPNA2,DVL1,ROCK1,RPS26,POT1,TBC1D12,RPS15,PHB2,LAMTOR3,NKD2,TIA1,RPL15,RAB6A,XPO7,RAPGEF6,RHBDD1,PRPF18,NUP205,RB1,KIF13B,PPIL2,ARL6IP1,YBX1,KDELR1,RPL6,KRAS,SYVN1,ZDHHC3,BBS12,RPL36,PCM1,GOLGA4,SIL1,NUP62,CTSA,YWHAZ,RUVBL2,TOB1,SNX27,TOMM20,RPLP2,DYNLL1,TOR1AIP1,RRAGC,TWF2,RPAIN,BCAP31,RPL11,MDM2,SAR1A,BCAP29,CLTB,AHCYL1,LMAN1,F2R,DVL2,PRPF19,RPL29,RPL35,NXT1,RAB7A,TOR1AIP2,NUP155,TOLLIP,RPS9,RPSA,SURF4,TULP3,TIMM17A,ARNTL,AP1S1,CHMP4B,FAU,SMURF1,MAPK1,TSPAN5,AP2S1,PARD3,TMEM33,KLHL21,RAE1,EYA1,SRGN,DCTN2,NUP54,VPS45,GGA2,AP3S1,SEC24C,ARHGEF2,H2AFY,STAT3,MYO5A,TGFB1,ZDHHC18,SNX2,MAPK3,MFN2,RAB18,PDCD6,ATP6V1D,SEC23IP,KPNA4,GOLGA7,OSBPL8,FAM126A,PKD2 |
| 1.176e-18 | -41.28 | GO_REGULATION_OF_CELL_CYCLE_PROCESS | MSigDB lists | GO_REGULATION_OF_CELL_CYCLE_PROCESS | 532 | 159 | 17377 | 2626 |
UBE2E2,PDCD6IP,GPR132,THOC1,CUL1,CSNK2A1,SIRT2,CCNB1,BECN1,FANCI,CALM2,CDK5,PCNA,PSMD1,NEK6,CDC42,CDC25B,ECD,CARM1,CDC5L,PLK3,PLK1,AKT2,LRP5,CDC6,AURKB,BRCA1,SOX4,CCNF,ANLN,RPS27A,PSMD8,E2F4,ZNF268,CHEK2,VPS4A,TFDP2,PSMC1,SLC25A33,CLSPN,GORASP1,PHB2,CENPF,CTCF,KIF23,RACGAP1,CDK13,PSMD9,CRLF3,CDC73,SPAG5,CNOT3,TFAP4,RB1,PDXP,SMC3,CCP110,FBXO7,MSH2,BCL2,KNTC1,TERF2,PSMA1,PSMB3,RBM38,DAPK3,PSMC4,GOLGA2,CDC27,CDCA5,FAM83D,CNOT6,ZNF830,CDK2,CDKN2A,ZNF207,CHMP2A,FOXM1,CAST,PTTG1,TPX2,SMARCA4,ORC1,PRKACA,APP,MDM2,PSMA6,CCNA2,KIF14,PIN1,CDKN1B,ANAPC7,CTDSP2,RPRD1B,PRPF19,BRD4,PSRC1,PSMA8,BTG2,CUL3,PSMB7,NUSAP1,PKMYT1,CDC23,CHMP2B,RAB1A,PSMB9,RAD51C,CDC16,NSMCE2,PSMD3,UHRF2,CHMP4B,XRCC3,GEN1,MIF,KIF3B,PKP4,KLHL21,TCF3,CDT1,BLM,RAB11A,MAD2L2,FBXO5,CCNK,RPA2,RFWD3,PSMD2,PTEN,CENPJ,AXIN2,BRD7,FEM1B,H2AFY,GTSE1,CNOT6L,TGFB1,PPP1R9B,ADAM17,RHOA,HMGN5,PRKDC,ANAPC2,PRMT2,MEN1,BORA,KIF11,SH3GLB1,BIRC5,TFDP1,E2F1,PML,PKD2,UBE2C,TERF1,ESPL1,DDB1,ANAPC4 |
| 1.229e-18 | -41.24 | lung-carcinoma | COSMIC cancer mutations | lung-carcinoma | 4311 | 823 | 17385 | 2587 |
FGFR1OP,RAB14,KDM4A,PIGQ,XIAP,DHX8,LACTB2,PPP1R16B,ZNF275,FBXO22,EEF2K,CDKN2C,CDK5,NEK6,RABGAP1L,RAD23B,SRSF4,UPRT,NUP153,RNF26,SENP1,PCBP2,MLST8,PLK3,BAK1,ERCC1,RHOBTB3,NRAS,GABPA,TOPORS,MCL1,PPFIA3,SMC2,ICMT,MCM2,RAB22A,ARF4,KRIT1,TRIM47,SMAD2,MID1IP1,RAD18,WDR11,LIMK1,AXIN1,OGT,RNASEL,TFDP2,FBXL3,SMAD1,E2F2,PFKP,PDCD4,NXT2,DDX42,SSRP1,CLSPN,KIAA0100,RHOC,TRIO,RAB23,CERK,TOP2B,EZH1,EIF2AK4,PDCD7,ITGB5,APH1B,LMNA,MCTS1,ATG4A,DDX56,SLC38A5,INPP5A,RNFT1,MCM5,FBXO7,PHF14,FOXN2,GEMIN4,PHKG2,NUP85,SRSF11,ETV3,DHX29,MYBL2,USP10,ITM2A,BCLAF1,SRSF5,MPG,ELK1,RHOB,PTPRF,MAGED2,DTWD1,KPNA1,ETS2,DUSP3,MDH1,NDE1,RNF139,SNX14,ALS2,EGLN1,RHOG,TRIM41,TRERF1,CHD1L,PTTG1,TPX2,MYH9,NUF2,PRKACA,KTN1,RAB21,PRKD3,FBXL6,DUT,UBA5,NUP107,ANAPC7,RNF19A,RBM15,ARL5A,SNX8,GOPC,IDH3A,MAP4K4,CIRBP,E2F3,DNAJA1,MEF2D,RAB1A,TAZ,FKBP3,DDX17,KIF2A,TAF2,PPP2CA,CDC16,LSM6,CORO1C,HIPK2,RNF38,FUS,PDXK,PPP5C,GEN1,USP13,SESTD1,SRSF6,SIKE1,IP6K2,UBE4A,SLC25A43,ETS1,IFT27,IL21R,NEIL2,FBXO3,RPA2,PPP1R3B,ERH,PDCD10,CLIC4,SUV39H2,ITGB8,HUWE1,PPP1R8,ARF5,ARHGEF1,GEMIN6,UBE3B,FBXL19,GTF2H2,IMPA2,LDHB,PDPK1,STAU1,PPP3CA,TK1,TNFAIP3,DDX24,POLK,LDHA,MTMR12,RAB3IP,DDX39A,PICALM,RPA1,KEAP1,MAGT1,POLE,CCDC6,WNT5B,PITX1,MAPK6,FAM3C,PML,AEN,HMGB2,RGL1,CD81,YWHAH,IGBP1,ANAPC4,FAF1,COX15,DDX47,TRIM11,PPP1R15B,WDR13,SNX15,CSNK2A1,GIT2,BIRC2,FANCL,ABL2,RAB8A,PCNA,NUP210,NT5DC1,IL6ST,ETV6,XRCC2,PIK3R2,ZFYVE27,MYBL1,ASB6,VPS13B,PTPRK,PLK1,SP3,PTPN18,SEPT9,RBX1,RAD51AP1,SNRPB,TLK1,GMFB,LNX2,CDC6,LRP5,UBE2V1,BRCA1,UTP3,RAB5B,USP21,RHEB,TRIM4,FBXO28,CHD3,E2F4,SOCS4,BCL7C,ADAM9,KPNA2,ACTB,DVL1,NUDT11,POT1,NUMB,FUBP1,DNAJB2,NKD2,LAMTOR3,COX4I1,RACGAP1,CDK13,ADCK5,PPP3CB,DNAJB1,RAB6A,RAPGEF6,NUS1,VMP1,MBD2,XPA,RBM3,AFF1,GLE1,MAML1,CYTH1,ABHD2,TRAPPC9,NSDHL,ACSL3,LDB1,KRAS,EIF2AK1,MAP4K3,UBE4B,ICAM2,IRF5,SDHB,MBIP,PALB2,CDC27,PRPS2,COX7A2L,ZDHHC7,RUVBL2,CCNB2,USP7,SART1,TRAF7,FOXM1,XAB2,SUMO2,LAGE3,DUSP22,LYN,PCBP1,BCAP31,RAD23A,RPL11,CSDE1,VAV1,MRPL50,PDK2,PSMA6,MDM2,WDR44,PIN1,PDCD2,CORO1A,MINPP1,STRAP,SAP30L,SPSB3,DVL2,KDM3B,SNX25,ARHGAP17,BIRC3,RAB7A,BTG2,DNAJC9,NUP155,DCLRE1C,CHMP2B,ARL5B,EIF3H,USP36,SRSF1,DNAJC10,PLEKHG4B,RBL1,CLK3,DHX16,STK38,MAFK,FASTK,UHRF2,DNAJC17,AP1S1,XRCC3,NCOA1,USP53,SMAD4,RAD51D,INTS2,BCL2L12,MCM10,GOLIM4,CDT1,ARID5A,SMC6,HMGN3,NKRF,ARF1,CSNK1A1,SCYL2,FZD6,DNAJB9,TFRC,PTPN2,HERC3,IRF4,DDX31,ABCD1,SS18L1,ORC3,CAMK2G,RNF5,RHOA,CNTN5,HMGN5,SNX2,TOP3A,ARHGEF12,PCGF1,DDX23,RAB18,TRIM26,FBXO41,KPNA4,ATP6V1D,PDCD6,BIRC5,TFE3,NEIL3,PGRMC1,E2F1,IMPDH1,USP20,RBPJ,NR2F2,RPS6KC1,UBE2C,PGAM1,HIPK3,PDCD6IP,MAX,NUP188,ADAM10,TSC22D3,CXXC1,USP39,CUL1,CCNB1,IKBIP,UBE2I,PARK7,RAB4A,SUCLG2,CDC25B,PLCL2,TFG,SMARCE1,DNMT1,CDC5L,ORAI2,KLF10,AKT2,PBK,GNG7,DDX20,AURKB,USP22,CCNF,SLC25A5,CBFB,RFC2,RAB2B,EIF3A,DOT1L,ZMYM3,MAP3K4,ANKRD10,HHEX,WAS,PTPN7,ITGB1,PTPDC1,TRAF5,ZMAT3,HDAC2,PTOV1,DDX58,RECQL,COX5B,DNAJC5,CHTF18,GSPT2,PRKAA1,VAV2,RRM1,KIF23,CYCS,NOTCH2,PSEN1,JMY,CFLAR,FKBP1A,RPN1,RNF121,MEX3C,SNX18,ATIC,HDAC7,PPP4R1,DAPK1,MSH2,FBXL7,CYC1,RNF135,PIKFYVE,GNAI2,ANKHD1,EEF1D,TERF2,SOCS5,PHF10,DDX28,PIGT,PRIM2,MFNG,PIP4K2C,RIT1,ARID1A,KDM3A,MAP2K2,PHF6,PI4K2A,AKAP1,HMGN2,FAS,XRCC5,ADSS,DERL1,CAT,PFDN5,TMEM54,ZFP92,RBMX,ACLY,USP32,PPP3R1,PIAS2,VCPIP1,GPI,MAP3K5,YY1,CDK2,RNF14,NRBP1,CDKN2A,DNMT3A,TP53RK,REPS2,TRIP10,RAB11B,SUZ12,RPS6KA1,SF3B1,RAF1,MAGED1,RAC1,BCL2L1,GNB2,SDHA,EPM2A,TERF2IP,PHC2,CRKL,ZNF75D,CCNA2,KDM2A,SHC1,SIAH1,RALB,LPIN2,SOCS6,TNPO2,CDKN1B,TP53BP2,CDK12,SAP30,CCT2,MAPRE2,RFC3,BRD4,ERF,HMGN4,NARF,CUL3,PKMYT1,CDC23,ASB13,POLG2,EML4,ERC1,TRIM28,DHX57,ANKZF1,RAD51C,HSPA4,JAK1,PPP2R5A,ACYP1,SAFB,FTSJ1,SEL1L,H2AFX,STAT1,TRIM32,PDCD11,XRCC4,RHEBL1,ADAM23,PRPF4B,POLQ,OTUD5,NCOR2,MECP2,TCF3,CBLL1,LANCL1,BLM,RAB11A,FOXO3,POFUT1,HMG20A,MAD2L2,PIP5K1C,EBP,JAKMIP1,WWP2,PTEN,AHSA1,PTPN11,AXIN2,COPS7B,UBE2M,NCOA2,MSH6,SMC4,JMJD4,LONRF3,NET1,NEK7,ADSL,FBXO9,RABIF,ANAPC2,KIF11,MARK2,TSR2,FADD,CBX3,PLD3,GNA12,FBXO21,PFDN4,MFAP1,TFDP1,KHSRP,PPP1R11,DDX5,DUSP11,BRWD3,ESPL1,GPR89B,DDB1,DEF6,IPO4,RORB,POLA2,IER2,PIGM,UBE2E2,ST13,NF1,UBE2Q1,PTP4A3,AGFG1,KIF2C,SIRT2,UBQLN2,FKBP2,USP48,BECN1,MAPK14,RNF103,MBD4,RAP1A,CDC42,EIF4A3,THADA,RAB35,JAZF1,PPP1R12C,RP2,TCEA1,OGG1,ARID4A,TRIM14,SRPK2,COPS8,TRIM8,NCK1,VHL,RRM2,WDR82,PITPNB,SOX4,KMT2C,STK17B,CXXC4,PAF1,GEMIN5,UEVLD,PPM1G,PQBP1,CAB39,STK11,CHEK2,CLU,COPS6,MRPL13,UBE2D3,PIGN,PPP1R12A,PPP1R2,NACA,CIB1,PCSK7,MED13L,THRAP3,XPO7,RGS2,NUP205,ZNF449,BCL2,KNTC1,UBE3C,ZRANB1,MCPH1,N4BP2,CSNK1G3,ALDH9A1,ZNF189,ARHGAP15,DAPK3,MASTL,UAP1,KLHL15,SIAH2,PITPNA,NUP62,YWHAZ,RBBP4,TOB1,SMARCD1,MBD1,WASF2,TCF12,PRKAB1,SNX27,ASH1L,MDH2,PMS2,PLAGL2,SMARCA4,ORC1,TWF2,CHD1,MXD1,USP5,SAR1A,AKAP8,PPP6C,CS,APOOL,FAM3A,SCYL3,ABI1,DNAL4,RLIM,MOSPD1,EBAG9,POU2AF1,RNF25,METTL2A,PCGF6,GLO1,BICD2,OGDH,FANCE,PDHX,RAD54B,DAP3,TAB2,TULP3,HPS5,STAT6,FKBP5,SCARB1,GAS2,USP11,SMURF1,MAPK1,PPP2R2D,CBX4,DNAJC2,MAGEH1,CDS2,SH2D3A,CASP6,EYA1,RAE1,SCYL1,DBF4,NUP54,CHIC2,MXD4,PIP4K2A,RGS1,FBXO5,KIF5B,FGFR3,CTNNBL1,TANK,ARHGEF2,STAT3,FRMD8,AMPD2,CSNK1G2,HMGN1,ADAM17,DCAF6,MAPK3,TFEB,MTMR3,COX8A,SRSF3,IDH3B,ZMIZ1,HRAS,TERF1,RAB3IL1 |
| 1.273e-18 | -41.21 | GARY_CD5_TARGETS_DN | MSigDB lists | GARY_CD5_TARGETS_DN | 410 | 132 | 17377 | 2626 |
POLA2,MAX,NOP2,RBM8A,ENSA,YTHDF3,EBNA1BP2,SNRPD3,IKBIP,COMMD5,CCNB1,RBM4,PAPOLA,CREM,PSMD1,NOL11,THADA,SLC44A1,SRI,EIF5,MYBL1,MRPL32,CCAR1,SRSF10,KLF10,GMFB,RRM2,DDX20,GALNT7,UTP3,PBRM1,RFC2,PLEKHF2,FBXO28,ZNF367,PQBP1,QRSL1,COX5A,KPNA2,ATP6V0E1,FUBP1,PPIB,PRPF38B,HSPH1,CLSPN,GSPT2,CENPF,DHX9,TIA1,KLC1,KIF23,SRRT,DTL,RBM3,GEMIN4,SRSF11,DHX29,AMD1,GTPBP4,UTP15,BCLAF1,MATR3,TWISTNB,SERTAD2,SYNCRIP,CDC27,RBM25,RBMX,ZBTB24,ZNF207,BCCIP,MRPL50,FLAD1,OIP5,FARSA,TNFAIP8,MTMR4,KIF14,GRSF1,UCHL5,TNPO2,TARDBP,ANAPC7,PDIA6,CDK12,RLIM,RFC3,DNAJC9,NLN,KIAA1586,DNAJA1,ARL5B,GAR1,SRSF1,DNAJC10,IDE,HSPA4,HINT1,H3F3A,TMEM33,INTS2,RRP15,SDF2L1,ETS1,PNO1,TFRC,FBXO5,PPIG,TANK,ANP32A,GEMIN6,CITED2,GTF2H2,FRMD8,HNRNPM,NUDC,GINS1,NASP,ABCF2,ILF3,ADSL,PPWD1,ZNF407,API5,SEC23IP,PLAA,MAGT1,BIRC5,SLC25A19,SRSF3,ATP6V1C1,GPATCH4 |
| 1.425e-18 | -41.09 | ITGA4 (integrin subunit alpha 4) | protein interactions | 3676 | 517 | 163 | 17029 | 2761 |
SRM,PDCD6IP,NUP188,HNRNPAB,COPA,AGFG1,SND1,SNRPD3,RBM4,PABPC4,RPL23A,PA2G4,NUP210,EIF4A3,PIK3R2,TTC9C,SRI,DNM2,AP2B1,LRRC59,PCBP2,PTPRK,LARS,SNRNP200,NSUN2,MRPL43,HNRNPF,ESYT1,MCM2,SLC25A5,DHX15,EIF3A,RPS27A,RPS14,ITGB1,ATXN2L,KPNA2,ACTB,MYL12B,PFKP,CAPN1,SSRP1,DDX42,FUBP1,EWSR1,MAPRE1,PHB2,TIA1,EPN1,CYCS,NUP205,LMNA,VASP,MCM5,EFTUD2,CAPZA1,YBX1,RBM3,PABPC1,EEF1D,HP1BP3,EIF3L,NTPCR,SF3B6,MEMO1,RPS10,PSMA1,RPS24,PLEC,SEPT7,PKM,EIF4G2,CCT8,MATR3,XRCC5,RPL36,SEC31A,SDHB,EPRS,SYNCRIP,RBMX,YWHAZ,SNRNP70,HNRNPDL,CHMP2A,IMMT,NQO1,MDH2,SLC2A1,RAC1,MYH9,PCBP1,GLRX3,STMN1,PRKACA,SDHA,RPL11,HNRNPA2B1,DECR1,PSMA6,IARS,PIN1,TARDBP,CFL1,CCT2,RPL35,SEC61B,RPL38,VDAC2,TRIM28,RPS9,RPSA,DDX17,EIF3K,PPP2CA,AFDN,PON2,HNRNPR,PSMD3,CHMP4B,FUS,H3F3A,AP2S1,MIF,RPS2,ARF1,ATP5F1B,CSNK1A1,TFRC,FERMT3,GSTK1,PSMD2,PDCD10,NDUFA2,RPL17,SEC24C,ARF5,TAGLN2,TTLL12,FBL,UBE2M,HNRNPM,LYPLA2,NUDC,LDHB,PRKDC,ILF3,RPL8,LDHA,RPL27A,PICALM,TARS,PRDX1,HSPA1B,UPF1,PDCD6,PRDX3,HNRNPH3,LRPPRC,KHSRP,ACAT1,DDX5,CD81 |
| 1.566e-18 | -41.00 | GSE14415_TCONV_VS_FOXP3_KO_INDUCED_TREG_DN | MSigDB lists | GSE14415_TCONV_VS_FOXP3_KO_INDUCED_TREG_DN | 173 | 74 | 17377 | 2626 |
PTMS,NOP2,RBM8A,TPX2,NUF2,FKBP2,STMN1,COMMD8,SSR1,PA2G4,CCNA2,KIF14,CORO1A,LMAN1,LRRC59,TACC3,PLK1,RFC3,LAP3,PBK,SNRPB,KIF15,RRM2,WDHD1,BRCA1,SMC2,MCM2,SHCBP1,PDHX,PSMD8,TOMM6,CEP55,NRM,AP1S1,KPNA2,ANP32E,GEN1,PSMC1,SEPHS2,COX5B,CLSPN,CDCA8,RRM1,CDCA3,KIF23,RACGAP1,PMF1,NCAPG,DTL,ERH,SLC31A1,PPP1R8,NAA50,PRC1,AHCY,KNTC1,PPA1,GINS1,PIGT,FAM49B,CAPZA2,KIF11,API5,SNRPA,SMAP2,HMGN2,MTHFD2,ATAD2,BIRC5,PRDX3,TFDP1,WDR76,CCNB2,CDK2 |
| 1.648e-18 | -40.95 | UNK (unkempt family zinc finger) | protein interactions | 85451 | 293 | 109 | 17029 | 2761 |
RAB14,TXN,HNRNPAB,COPA,UGP2,SF3B1,PPP1R15B,ACTR3,GLUD1,ATP6V1B2,COMMD6,GGPS1,PCBP1,STAM,PARK7,CSDE1,CALM2,DST,RRN3,RAP1A,ATP2A2,CDC42,SAR1A,DPYSL2,TRA2B,TFG,PDIA6,MCMBP,RLIM,USP34,MKLN1,ATXN1,MCL1,NUP155,OGDH,RAB1A,TXNL4A,DHX15,ARF4,EIF3H,EIF3A,PPP2CA,HSPA4,HINT1,SAFB,LUC7L3,ITGB1,OGT,COX5A,ACTB,ANP32E,PDCD4,HDAC2,TUBB,MAPRE1,PHB2,UFC1,UBXN1,TOP2B,ARF1,IP6K2,PSEN1,COPB2,SRXN1,SUB1,PDCD10,HUWE1,ARF5,RTCB,ARL6IP1,H2AFY,TNPO3,YBX1,NAP1L4,PTGES3,TTLL12,RPL22L1,MSH6,TXNL1,ATP5IF1,FAM49B,C16orf72,MTA2,LDHA,KRAS,BCLAF1,ARID1A,EIF4H,EIF4G2,MATR3,CCT8,PICALM,POLR2A,CBX3,CAND1,PTPRF,KPNA4,PLAA,PRDX3,ACAT1,SLC16A1,YWHAZ,DDX5,ZRANB2,ATP5F1A,PPP6R3,IGBP1,UBE2C,HNRNPDL |
| 2.022e-18 | -40.74 | MANALO_HYPOXIA_DN | MSigDB lists | MANALO_HYPOXIA_DN | 267 | 98 | 17377 | 2626 |
SRM,POLA2,NUP188,GNPDA1,URB2,TPX2,USP39,EBNA1BP2,SNRPD3,CUTC,POLR3K,PAIP1,FANCI,OIP5,PA2G4,CCNA2,IARS,NOL11,CD3EAP,NVL,UCHL5,ATP13A3,POP7,PDCD2,GPD1L,SEH1L,NOL12,PPIF,RFC3,POLR2L,PBK,IDH3A,RAD51AP1,RRM2,DNAJC9,PSMG1,NUSAP1,CDC6,AMDHD2,BRCA1,PKMYT1,CCNF,MCFD2,MCM2,SHCBP1,ODC1,RFC2,ASF1B,CHAF1A,IDE,WDR4,H2AFX,NCLN,RRS1,LRP8,MCM10,HJURP,RRP15,C1orf112,TOR3A,DBF4,RRM1,KIF23,FAM136A,SRRT,RSAD1,NUP205,PNO1,FBXO5,RB1,GART,ATIC,MCM5,PRC1,GEMIN6,PCYT2,MRPL40,NUP85,GINS1,TELO2,NASP,ABCF2,ILF3,TOP3A,GTPBP4,ELK1,MFN2,DDX23,AKAP1,UTP20,SLC19A1,SLCO4A1,SEC23IP,TTLL4,PRMT7,BYSL,IPO4,GCSH |
| 2.204e-18 | -40.66 | transferase complex | cellular component | GO:1990234 | 804 | 212 | 18223 | 2701 |
MIB2,CCNC,POLA2,MAX,DCAF15,CXXC1,PIGQ,CUL1,TAF6L,CCNL2,SNRPD3,CCNB1,UBE2I,BECN1,POLR3K,ZER1,USF1,METTL14,ATG3,INTS1,PIK3R2,TAF5L,TCEA1,SPTSSA,ZNRD1,WDR41,METTL1,ERCC1,DPM1,RBX1,SNRPB,VHL,WDR82,TOPORS,UBE2V1,SUPT20H,USP22,DCUN1D5,BRCA1,CCNF,KRTCAP2,KMT2C,CLNS1A,PRIM1,PAF1,RAD18,STT3A,WDR4,OGT,CRCP,CAB39,DHTKD1,ACTB,KLHL42,FBXL3,DCAF5,HDAC2,NSMCE4A,POLR2K,ZNF768,PRKAA1,KCTD17,CDK13,EZH1,SUPT7L,METTL3,CDC73,DTL,RPN1,RB1,MED8,KLHL5,MED10,INTS7,PYURF,DAD1,FBXO7,ZNF335,CTR9,FBXL7,PHKG2,POLR2I,PRIM2,RB1CC1,DCAF8,TEX10,RTF1,UBE4B,SYVN1,PKM,TWISTNB,CAND1,MBIP,FNTA,ORMDL2,POLR2J,CDC27,EPOP,KLHL15,PRPS2,DCAF11,PTAR1,TBPL1,RUVBL2,RBBP4,MAP3K5,NAA20,RNF14,CDK2,SGF29,PDSS2,BCCIP,PRKAB1,TRAF7,MPHOSPH8,SUZ12,UBR2,KLHL18,ANKIB1,MEAF6,PHC2,CCNA2,BABAM2,BRPF3,DDA1,CDKN1B,INTS12,ANAPC7,RPN2,RNF19A,NAA35,CDK12,RPRD1B,SPSB3,POLR2G,POLR2L,PGGT1B,KAT7,PCGF6,CUL3,POLR2D,ELP4,EDF1,OGDH,DNAJA1,CDC23,PEF1,ERC1,BTBD1,MAT2A,TAF2,CDC16,DDOST,NSMCE2,SEL1L,SNRPG,CBX4,INTS2,CTDP1,KLHL21,TRMT6,SMC6,CBLL1,BRAP,GMCL1,UBE4A,WDR5,DCUN1D4,PAGR1,MAD2L2,NEXMIF,WWP2,GTF2F1,CCNK,MAT2B,ERH,KLHL20,PRDM4,NAA50,H2AFY,ATG13,KANSL2,POLR1B,OSTC,FBXL19,GTF2H2,DCAF6,RPRD1A,ZFP64,KAT2A,HELB,POLR3GL,FBXO9,ANAPC2,MEN1,POLR2A,HSPA1B,FBXO21,KEAP1,PDCD6,MAGT1,POLE,GOLGA7,PRDX3,KBTBD7,KMT2B,TAF12,TAF6,UBE2C,ANAPC4,DDB1,ZSWIM6 |
| 2.211e-18 | -40.65 | MORF_EI24 | MSigDB lists | MORF_EI24 | 138 | 64 | 17377 | 2626 |
TMEM106C,IMMT,H2AFZ,HNRNPAB,DYNLL1,RAC1,STARD7,CCNB1,SDHA,BCAP31,RAD23A,CALM2,HNRNPA2B1,IARS,GOT2,CS,TCEA1,SNRNP200,PPT1,VDAC2,GLO1,MCFD2,VDAC1,SERP1,RHEB,SRSF1,ALG3,PPM1G,BAZ1B,SCARB1,AP2S1,HDAC2,SSRP1,NCOR2,TM9SF4,CYCS,XPO7,HDDC2,EIF2S2,NDUFV1,SEC24C,AHSA1,EI24,PTGES3,NUDC,IFRD1,MLEC,POLR2I,NSDHL,PRKDC,TUFM,ABCF1,TARS,SNRPA,SDHB,EPRS,PRDX3,MFAP1,PRPS2,KHSRP,MDH1,NUP62,RUVBL2,SSSCA1 |
| 2.261e-18 | -40.63 | GO_MITOCHONDRION | MSigDB lists | GO_MITOCHONDRION | 1465 | 342 | 17377 | 2626 |
TXN,NDUFB6,MRPS15,ZDHHC8,TAP1,GLUD1,LACTB2,OAT,PARK7,SLC25A37,C14orf119,NAPG,MECR,SUCLG2,CISD2,LRRC59,BAK1,HSDL1,MRPL43,LACTB,MCL1,SLC25A5,FOXRED1,STOML2,RPS14,PRDX5,MRPL27,MPV17,OGT,MLYCD,DHTKD1,COX5A,UQCRH,RNASEL,SLC25A33,COX5B,NDUFV2,MRPL9,DNAJC5,MUT,MRPS2,ADO,CERK,NDUFA4,CYCS,PSEN1,NDUFS7,NDUFS4,C12orf10,ATIC,BDH1,FBXO7,CYC1,MRPL40,MRPL21,TNRC18,NSUN4,CARS2,TIMM8B,DDX28,NOA1,DHX29,PGS1,MRPL16,MTX1,TOMM40,MPG,ELK1,MAP2K2,SFXN5,PSMB3,CYB5A,AKAP1,PI4K2A,CAT,MTHFD2,QARS,PPP3R1,MDH1,MRPL3,ACSF2,CDKN2A,FAM72A,KARS,ATXN3,RAB11B,RAF1,STARD7,NIT2,BCL2L1,SLC25A44,SNN,PRKACA,SDHA,MOAP1,NUDT19,FLAD1,DECR1,SHC1,DUT,GRSF1,MRPS27,MAVS,TP53BP2,ATF2,GPX4,IDH3A,VDAC2,ABHD11,DNAJA1,NDUFA7,TAZ,POLG2,DHX57,ANKZF1,PPP2CA,CHCHD3,RAD51C,MRPL55,RAB24,PPA2,PITRM1,EYA2,NDUFS1,ANXA6,MECP2,TRAK1,SLC25A12,ARGLU1,SECISBP2,SLC25A43,RAB11A,SLC25A36,MAT2B,CLIC4,GATC,NDUFA2,COQ4,PTEN,NDUFB4,CRAT,PTPN11,MRPL54,CREB1,NDUFA3,MTX2,PACS2,LDHB,TMEM160,PPP3CA,NUDT8,TMEM126B,MRS2,JTB,ILF3,TBRG4,MRPS10,HEBP2,RHOT1,GUF1,MARK2,SH3GLB1,PRDX1,ECH1,SH3BP5,PFDN4,PRDX3,PARG,ACOX1,TFDP1,LRPPRC,SLC25A19,NDUFS5,PSAP,YWHAH,HIGD2A,COX15,LYRM4,MTX3,UQCR10,MCCC1,ABCB10,SND1,USP48,BECN1,MAPK14,MAP1LC3B,MRPL19,ATPAF1,PRNP,BCAT2,GOT2,TIMM23,DPYSL2,SIVA1,RAB35,TRMU,SLC44A1,HADHB,SRI,NDUFB9,NFU1,OGG1,MRPL32,TIMM50,HARS,LAP3,VHL,MRPL12,SLC25A22,LRP5,BRCA1,SOX4,TIMM13,IARS2,QRSL1,STK11,CLU,OSGEPL1,CLN3,DNAJC30,MRPL13,DCAF5,CAPN1,CTU2,PHB2,CHCHD2,COX4I1,XPNPEP3,RGS2,LYRM2,RSAD1,RHBDD1,APOPT1,BCL2,MRPL48,ACAD8,ALDH18A1,NIPSNAP1,OXR1,ACSL3,KRAS,THNSL1,SDHB,COX7A2L,SLC16A1,YWHAZ,PDSS2,NDUFA5,MMACHC,IMMT,TOMM20,SUCLG1,NDUFAF2,MRPL39,DYNLL1,MDH2,ZADH2,LYN,BCAP31,CSDE1,MRPL50,PDK2,CD3EAP,NVL,PIN1,AKAP8,MRPL34,CS,PARL,CYB5R1,APOOL,TOP1MT,TMEM14C,GM2A,HTRA2,ACSL5,PPIF,COQ10B,CPOX,NLN,BOLA1,OGDH,CHMP2B,VDAC1,NDUFB1,MRPS14,GFER,PDHX,GLOD4,MRPL2,PON2,DAP3,IDE,TOMM6,TIMM17A,CHCHD1,FASTK,NDUFA11,XRCC3,SPRYD4,SMURF1,MAPK1,SLC25A39,PDF,CDS2,RRP15,MRPL42,MRPS26,LETMD1,GFM2,TFRC,HDDC2,GTPBP3,FASTKD3,GSTK1,NDUFV1,ABCD1,ATG13,NDUFS8,MRPL11,STAT3,RNF5,SLC25A1,TXNL1,HEMK1,TIMMDC1,ZNF202,ABCF2,TUFM,WDR81,RHOT2,HAGH,CHCHD6,MAPK3,MFN2,COX8A,E2F1,ACAT1,ACADM,IDH3B,GCSH |
| 2.656e-18 | -40.47 | GO_SPINDLE | MSigDB lists | GO_SPINDLE | 272 | 99 | 17377 | 2626 |
ZNF207,SKA3,CYLD,DYNLL1,POC1A,XIAP,TPX2,MYH9,SIRT2,CCNB1,MAPK14,BIRC2,APP,KIFC1,CALM2,NEK6,CDC42,KIF14,KIF22,CDC25B,CEP63,DCTN1,PRPF19,PLK1,PSRC1,BIRC3,NSUN2,CUL3,TUBGCP5,KIF15,CKAP2L,NUSAP1,TOPORS,CDC6,AURKB,DIDO1,SLC25A5,KIF2A,PPP2CA,CDC16,KIF18B,MAP4,VPS4A,MAPK1,CSNK1D,ANXA11,KIF3B,CTDP1,PKP4,MAPRE1,MZT1,KLHL21,CENPF,CDCA8,KIF23,HAUS4,RACGAP1,RAB11A,HAUS2,TUBGCP2,MAD2L2,NEIL2,SPAG5,SAC3D1,FBXO5,CEP104,RB1,SMC3,MZT2A,PRC1,ARHGEF2,KIFAP3,KNTC1,NUP85,KAT2A,ASPM,NEK7,PARP4,JTB,RANGAP1,MAP7D1,SEPT7,KIF11,HAUS8,CBX3,KIF18A,GOLGA2,CDC27,BIRC5,FAM110A,ODF2,FAM83D,NUP62,PKD2,WDR62,NDE1,MZT2B,ESPL1,TERF1 |
| 2.848e-18 | -40.40 | mitotic nuclear division | biological process | GO:0140014 | 152 | 68 | 17256 | 2622 |
BCCIP,ZNF207,CHMP2A,PDCD6IP,XIAP,TPX2,NUF2,KIF2C,CCNB1,BECN1,BIRC2,MIS12,KIFC1,ABRAXAS2,KIF14,AKAP8,PDS5B,KIF22,SEH1L,PLK1,PSRC1,BIRC3,CUL3,TUBGCP5,NUSAP1,SMC2,AURKB,CHMP2B,CDC23,KIF2A,CHMP4A,DSN1,KIF18B,CEP55,CHMP4B,CHEK2,VPS4A,RRS1,PPP2R2D,KIF3B,CTDP1,MZT1,PHF23,CDT1,CDCA8,KIF23,RACGAP1,SPDL1,NCAPG,RAB11A,TUBGCP2,SPAG5,RB1,NAA50,PRC1,SMC4,RHOA,MYBL2,KIF11,KIF18A,GOLGA2,BIRC5,CDCA5,NUP62,NDE1,CHMP7,UBE2C,ESPL1 |
| 2.904e-18 | -40.38 | GSE9006_HEALTHY_VS_TYPE_2_DIABETES_PBMC_AT_DX_UP | MSigDB lists | GSE9006_HEALTHY_VS_TYPE_2_DIABETES_PBMC_AT_DX_UP | 182 | 76 | 17377 | 2626 |
SART1,RPLP2,MRPS15,XAB2,MDH2,MYH9,GLUD1,SAFB2,BECN1,PCBP1,MEAF6,CALM2,MTA1,ILKAP,CFL1,CDC37,DEAF1,DRAP1,MRPL12,RNPS1,EDF1,NUTF2,EDEM2,RPL37,CHCHD3,CDCA4,HNRNPR,LIMK1,SAFB,SH3GLB2,BCL7C,COX5A,BTF3,VPS4A,NAA60,CBX4,SSRP1,NADSYN1,ANXA6,SEC61G,PDAP1,TKT,MFSD10,CNOT3,SAC3D1,GTF2F1,C12orf10,ERH,RPN1,SSBP3,ARHGEF1,YBX1,OSTF1,RBM3,AHCY,COPS7B,NDUFS8,MVP,HNRNPM,SLC25A1,PDLIM2,TGFB1,WDR18,MFNG,EIF4H,SF3A2,MAP2K2,FBXO41,LTBP4,GPS2,DBI,LPCAT4,SPCS3,CD81,HRAS,ADNP2 |
| 2.956e-18 | -40.36 | ESR1 (estrogen receptor 1) | protein interactions | 2099 | 783 | 221 | 17029 | 2761 |
CCNC,HNRNPAB,TSC2,NOP2,PRKCSH,TAP1,CUL1,AGFG1,SND1,UBE2I,MAPK14,RPL23A,PA2G4,USF1,PSMD1,EIF4A3,PIK3R2,NUP153,CDC25B,TECR,SMARCE1,FTSJ3,SRPK2,SP3,LARS,RBX1,AKT2,MKI67,HNRNPF,BRCA1,SMC2,UTP3,SLC25A5,DHX15,UBTF,AHNAK,SMAD2,RPS14,LUC7L3,U2SURP,PQBP1,ACTB,BTF3,RPS26,HDAC2,FUBP1,PPIB,HSPH1,EWSR1,POLR2K,PHB2,GADD45G,DHX9,TIA1,TOP2B,THRAP3,DNAJB1,MYL6B,LYAR,RPN1,SMC3,EIF2S2,MED10,HDAC7,MBD2,EFTUD2,RTCB,MSH2,YBX1,UBE3C,MVP,GNAI2,PABPC1,EIF5A,POLR2I,MTA2,LDB1,RPL6,GTPBP4,SEPT8,RPS24,BCLAF1,UBE4B,ARID1A,PLEC,SRSF5,MPG,XRCC5,RPL36,CAT,TSC1,EPRS,SYNCRIP,PDLIM1,GOLGA2,POLR2J,NSF,RBMX,PIAS2,ZDHHC7,TCOF1,RUVBL2,RBBP4,RNF14,CDK2,SMARCD1,KARS,SARNP,SF3B1,RPS6KA1,SUZ12,ACTR3,MYH9,SMARCA4,NSD3,AP1B1,PRKACA,SAFB2,GNB2,RPL11,HNRNPA2B1,FARSA,DECR1,RBM23,MDM2,SHC1,DUT,MTA1,AKAP8,RPN2,CFL1,EBAG9,PRPF19,RLIM,CCT2,SHOC2,RPL29,SEC61B,POLR2G,POLR2L,WBP2,POLR2D,CUL3,CIRBP,DNAJC9,BUD13,PSMB9,TRIM28,RPS9,RPSA,SRSF1,SUPT16H,DDX17,TAF2,PPP2CA,DNAJC10,DAP3,HSPA4,HNRNPR,TAB2,SAFB,CORO1C,GADD45B,H2AFX,FKBP5,FUS,NCOA1,H3F3A,PPP5C,MAPK1,SMURF1,SMAD4,TUBB,PRPF4B,SLC30A9,NCOR2,RPS2,TRIP12,SRSF6,ARID5A,CBLL1,ATP5F1B,CDK11B,WDR5,NCAPG,PAGR1,FOXO3,SCYL2,TFRC,PTEN,RPL17,AXIN2,ANP32A,RPL19,POLR1B,NAP1L4,PTGES3,STAT3,NCOA2,HNRNPM,SMC4,SPTAN1,STAU1,CSRP1,PSPC1,PRKDC,WDR18,ILF3,RPL8,PRMT2,MEN1,RPL27A,POLR2A,MAPK3,UPF1,ATAD2,SNAP29,E2F1,DDX5,SRSF3,YWHAH |
| 3.194e-18 | -40.29 | GSE22886_NEUTROPHIL_VS_DC_DN | MSigDB lists | GSE22886_NEUTROPHIL_VS_DC_DN | 186 | 77 | 17377 | 2626 |
ZNF207,TXN,SUCLG1,MRPS15,UROD,CUL1,ZFYVE21,CSNK2A1,SNRPD3,KTN1,PAIP1,ZNF804A,PSMD1,UTP18,GOT2,MRPL34,SUCLG2,TRA2B,SMARCE1,ATP13A1,PTPN18,RBX1,VDAC2,GLO1,UTP3,TMEM147,CBFB,PDHX,CLNS1A,ANKRD10,CHCHD3,IARS2,MPV17,UQCRH,PFKP,NDUFV2,NCOR2,NDUFS1,UFC1,ADO,HMGN3,MAN2B1,TMEM165,CAPN2,LRRC8D,NDUFB4,BANF1,FBXO7,ANXA5,YBX1,MDFIC,MRPL40,CYC1,UBE3C,CITED2,CYFIP1,SNX2,KIAA0930,TUFM,CCT8,APPL1,PRDX1,RPA1,YIF1A,SEC31A,DERL1,FBXO21,SGSH,MTHFD2,PRDX3,DUSP3,LRPPRC,SRSF3,EHD4,RNF14,CD81,FAF1 |
| 4.120e-18 | -40.03 | MORF_RRM1 | MSigDB lists | MORF_RRM1 | 96 | 51 | 17377 | 2626 |
RMND5A,IMMT,MAPRE1,H2AFZ,CHERP,CENPF,RRM1,STMN1,PABPC4,HDDC2,SPAG5,HNRNPA2B1,SMC3,IARS,GOT2,DUT,MSH2,CS,TRA2B,ANP32A,PTGES3,DNMT1,HNRNPM,NUDC,SNRNP200,NASP,PRKDC,VDAC2,DNAJC9,SLBP,VDAC1,MCM2,TXNL4A,KIF11,SNRPA,TARS,CHAF1A,SRSF1,XRCC5,HNRNPR,MFAP1,SAFB,PPM1G,TFDP1,LRPPRC,BAZ1B,KHSRP,RUVBL2,ESPL1,HDAC2,SSRP1 |
| 4.365e-18 | -39.97 | MORF_RFC4 | MSigDB lists | MORF_RFC4 | 143 | 65 | 17377 | 2626 |
IMMT,H2AFZ,NUP188,HNRNPAB,SDHA,PABPC4,RAD23A,HNRNPA2B1,CCNA2,IARS,GOT2,DUT,KIF14,MRPS27,CS,TCEA1,DNMT1,SNRNP200,RFC3,PPT1,VDAC2,DNAJC9,SLBP,MCFD2,VDAC1,MCM2,SERP1,CHAF1A,SRSF1,ALG3,HNRNPR,SAFB,PPM1G,BAZ1B,HDAC2,SSRP1,RRM1,CYCS,XPO7,SPAG5,HDDC2,EIF2S2,EI24,MSH2,TNPO3,PTGES3,MTX2,NUDC,IFRD1,MLEC,NASP,PRKDC,DDX39A,CDK11A,ABCF1,TARS,SNRPA,RPA1,EPRS,TFDP1,PRPS2,LRPPRC,KHSRP,RUVBL2,ESPL1 |
| 4.609e-18 | -39.92 | CYLD (CYLD lysine 63 deubiquitinase) | protein interactions | 1540 | 607 | 182 | 17029 | 2761 |
MIB2,DDX47,HNRNPAB,NOP2,CNTROB,SND1,SNRPD3,BIRC2,PABPC4,RPL23A,SF3B2,PRNP,PCNA,PSMD1,HADHB,TRA2B,PCBP2,CDC37,CDC5L,PLK1,MRPL12,MRPL43,HNRNPF,SLC25A22,AURKB,SLC25A5,DHX15,CLNS1A,EIF3A,OPTN,AHNAK,SPATA2,RPS27A,RPS14,U2SURP,OGT,ACTB,ROCK1,DVL1,MRPL13,PSMC1,RPS26,DDX58,PPIB,RPS15,HSPH1,MAPRE1,PHB2,DNAJB2,DHX9,KCTD17,RPL15,THRAP3,LMNA,EIF2S2,MCM5,EFTUD2,RTCB,CAPZA1,CTPS1,YBX1,MRPL21,MVP,PABPC1,EEF1D,EIF3L,PRRC2A,ACSL3,SF3B6,RPS10,RPL6,PSMA1,USP10,RPS24,BCLAF1,MRPL16,PLEC,SRSF5,CCT8,MATR3,RPL36,CAT,MAGED2,EPRS,NAP1L1,SYNCRIP,QARS,RBMX,ODF2,YWHAZ,RUVBL2,ATP5F1A,RBBP4,HNRNPDL,MRPL3,KARS,SART1,CYLD,RPLP2,TRAF7,CHERP,IVNS1ABP,MRPL39,MDH2,SF3B1,EIF3D,PMS2,MYH9,PCBP1,RPL11,SPINDOC,FARSA,PSMA6,IARS,GRSF1,TARDBP,PDIA6,CFL1,DCTN1,PRPF19,CCT2,RPL29,RPL35,PFKFB3,DNAJA1,RPS9,EIF3G,RPSA,EIF3H,MAT2A,SRSF1,DDX17,EIF3K,MRPL2,ATP1A1,HSPA4,SEC61A1,JAK1,HNRNPR,TAB2,PSMD3,STK38,RPLP1,FUS,FAU,TUBB,TMEM33,USP13,GALK1,RPS2,SRSF6,DCTN2,TIMM21,ATP5F1B,WDR5,RBM17,ERH,PSMD2,RPL17,RPL19,MRPL11,HNRNPM,MSH6,SPTAN1,STAU1,PRKDC,RPL8,ILF3,TUFM,BMS1,ARHGEF12,RPL27A,KIF11,PRDX1,HSPA1B,UPF1,RPL32,ACAT1,DDX5,SRSF3,DDB1,SSSCA1 |
| 5.509e-18 | -39.74 | nitrogen compound transport | biological process | GO:0071705 | 1655 | 377 | 17256 | 2622 |
CCDC93,TMED7,RAB14,NUP188,PDCD6IP,TSC2,TAP1,AP3M2,SYNRG,RIC1,PARK7,RPL23A,CDK5,NAPG,SNUPN,RABGAP1L,RAB4A,SRSF4,AP1M1,DNM2,AP2B1,NUP153,SEH1L,SRP72,PGAP2,USO1,TMEM115,ATG9A,AKT2,MCL1,PPFIA3,NUTF2,SLC17A5,ICMT,MCFD2,SLC25A5,RAB22A,RAB2B,ARF4,PLEKHF2,IWS1,HHEX,SMAD2,TMED10,RPS27A,RPS14,EIF2D,VIPAS39,ATP6V0C,BTF3,RRS1,ARRB2,NMD3,ZMAT3,LONP2,AAAS,SLC25A33,NXT2,GGA1,SEC61G,DHX9,RAB23,ACAP1,SLC35B1,TMED3,PSEN1,VPS25,COPG2,NPLOC4,COPB2,ATG4A,SLC38A5,SNX18,FBXO7,TNPO3,ATP6V0A2,MVP,CPSF4,SYTL3,NUP85,TMED2,SRSF11,NAGPA,EIF5A,TIMM8B,GCC2,RPS10,RPS24,SSR2,SRSF5,MTX1,TOMM40,PTTG1IP,GOSR1,RHOB,DERL1,SEC31A,SCARB2,KPNA1,NSF,PPP3R1,SNX14,NUP58,EXOC3,ANKRD27,NDC1,SARNP,SYS1,RAB11B,RAF1,GPR89A,ANK3,C5orf30,VTI1A,MYH9,TBC1D13,SLC35B2,AP1B1,STAM,CD320,RAB21,AHCTF1,TBC1D22A,TBC1D14,NUP107,TNPO2,TAP2,ZC3H3,ATP6V1G1,SNX8,SEC61B,GOPC,RPL38,POLR2D,RNPS1,SLBP,ATP6V0A1,RAB1A,AP4E1,ERC1,SERP1,PEX5,CHMP4A,HSPA4,SEC61A1,VPS26B,RAB24,RPLP1,SEL1L,PITRM1,RPS2,SCAMP3,SRSF6,MECP2,FLOT1,TRAK1,SLC25A12,BTN3A1,IFT27,RAB11A,JAKMIP1,SLC25A36,RPL17,ARF5,RPL19,UPF2,SLC38A10,MTX2,PPP3CA,GUK1,DENND1B,DENND4C,RPL8,RABIF,RAB3IP,DDX39A,MACF1,RPL27A,YIF1A,SLC19A1,KIF18A,HGS,RPL32,LTBP4,SLC38A7,STX18,LRPPRC,PML,KHSRP,SLC25A19,PSAP,YWHAH,VPS29,GPR89B,IPO4,SNAPIN,POLA2,MTX3,COPA,THOC1,NF1,RBM8A,SNX15,ALKBH5,UBE2Q1,SLC29A1,AGFG1,RUFY1,SEC16A,SSR1,RAB8A,NUP210,RAP1A,TIMM23,EIF4A3,AP3S2,RAB35,ATG3,SLC44A1,PIK3R2,RP2,SLC35C2,TIMM50,CDC37,VPS13B,FYTTD1,LARS,TLK1,SLC25A22,STX16,RAB5B,LSG1,OPTN,NECAP2,RPL37,TRAM2,TBC1D17,EIF4ENIF1,TIMM13,HSPB11,GRIPAP1,UEVLD,TIMM29,MIA2,ARRDC1,KPNA2,VPS4A,CLU,CLN3,RPS26,ATP6V0E1,C2CD5,TBC1D12,RPS15,GORASP1,PHB2,CENPF,RPL15,RAB6A,XPO7,RHBDD1,NUP205,RINL,KIF13B,ARL6IP1,GLE1,LRSAM1,SLC12A2,ATP6V0D1,PREB,ABCC1,KDELR1,RPL6,SYVN1,TMEM241,ZDHHC3,NPIPA1,RPL36,TSC1,GOLGA4,SNAP23,EXOC4,ZDHHC7,SIL1,NUP62,CTSA,CHMP2A,SNX27,CORO7,TOMM20,RPLP2,COPE,ATP6V1B2,LYN,RPAIN,BCAP31,RPL11,HNRNPA2B1,ANKLE1,ATP6V0B,SAR1A,AKAP8,BCAP29,SCAMP4,AHCYL1,CLTB,CHTOP,LMAN1,CHP1,SNX25,RPL29,NXT1,RPL35,PPT1,RAB7A,NUP155,BICD2,ERBIN,CHMP2B,RPS9,RHBDF2,RPSA,SRSF1,SURF4,VPS26C,TOMM6,TIMM17A,ARNTL,AP1S1,CHMP4B,SMURF1,AP2S1,ABCA1,PARD3,CDC40,GOLPH3L,RAE1,NUP54,VPS45,ARFIP2,TIMM21,ARF1,GGA2,AP3S1,TFRC,KLHL20,SLC1A4,SEC24C,RRBP1,SLC35B4,ARHGEF2,STAT3,SLC35A1,CAMK2G,MYO5A,TGFB1,ZDHHC18,NASP,SNX2,SCFD2,COG1,SYMPK,MFN2,RAB18,SEC23IP,KPNA4,UPF1,ATP6V1D,PDCD6,GOLGA7,SNAP29,RBPJ,SPCS3,SRSF3,ATP6V1C1,CHMP7,RAB3IL1 |
| 5.615e-18 | -39.72 | KIM_WT1_TARGETS_DN | MSigDB lists | KIM_WT1_TARGETS_DN | 421 | 133 | 17377 | 2626 |
WDR13,KIF2C,MAPK14,BECN1,MRPL19,PAPOLA,CREM,DPYSL2,DNAAF2,KIF22,SLC26A2,TECR,SPTSSA,MYBL1,SRSF10,RAD51AP1,ZBED5,AURKB,CCNF,RFC2,STK17B,TRAM2,BRWD1,C1orf109,ITGB1,MRPL13,FUBP1,HJURP,ZCCHC8,CENPF,TIA1,ASAH1,CTCF,KIF23,NDUFA4,RACGAP1,DNAJB1,TMEM165,METTL3,RSAD1,C12orf10,NFATC3,SMC3,ARL6IP1,CTR9,PIKFYVE,SRSF11,PRIM2,SUGP2,MAP4K3,FXR1,KDM3A,NMT2,AKAP1,RPL36,RDH11,ADSS,GNAS,RBM25,TBPL1,PRMT7,MZT2B,TOB1,GLT8D1,NDUFA5,CKLF,LAGE3,BCL2L1,RCOR3,STAM,OIP5,CRKL,FARSA,CCNA2,ZNF302,TNFAIP8,KIF14,GRSF1,ZCCHC2,MRPL34,CDKN1B,ATF2,PSRC1,EID1,DRAP1,CPOX,POLR2D,HTATIP2,NUSAP1,EDF1,H2AFV,SHCBP1,RPS9,SERP1,RAD51C,ACYP1,CEP55,GADD45B,PKP4,CDC40,GOLPH3L,CDK2AP2,DBF4,CDCA3,CDCA8,SDF2L1,NCAPG,SAC3D1,GSTK1,PPIG,GTSE1,CITED2,NCOA2,TMEM160,ZFP64,HEMK1,HMGN5,ASPM,DENND4C,NET1,TBRG4,RANGAP1,PPWD1,PCGF1,KIF11,KIF18A,MAGT1,PARG,CAPN7,HMGB2,NR2F2,ESPL1,IFI16 |
| 5.954e-18 | -39.66 | MORF_RAD21 | MSigDB lists | MORF_RAD21 | 169 | 72 | 17377 | 2626 |
NDUFA5,KARS,H2AFZ,HNRNPAB,RAC1,SUMO2,ENSA,STARD7,CUL1,SDHA,PARK7,BCAP31,MBD4,SF3B2,HNRNPA2B1,PCNA,UTP18,MTA1,RAD23B,EBAG9,SP3,CCT2,SNRNP200,POLR2G,DPM1,PSMB7,GMFB,RAB1A,PRPSAP1,RHEB,STOML2,KIF2A,PPP2CA,HSPB11,PSMD8,COX5A,KPNA2,SNRPG,PSMC1,COIL,MYL12B,HDAC2,SMNDC1,NDUFS1,MRPL9,SEC61G,NACA,DCTN2,CTCF,COX4I1,AP3S1,BANF1,BUD31,MSH2,CYC1,MAML1,HNRNPM,TMED2,EEF1D,IFRD1,HMGN1,POLR2I,ILF3,EIF4H,CBX3,RPA1,PDCD6,SYNCRIP,RBMX,COX7A2L,MDH1,WIPI2 |
| 6.777e-18 | -39.53 | ROME_INSULIN_TARGETS_IN_MUSCLE_UP | MSigDB lists | ROME_INSULIN_TARGETS_IN_MUSCLE_UP | 404 | 129 | 17377 | 2626 |
UBL3,H2AFZ,ST13,GNPDA1,TMEM41B,TMEM109,ENSA,TGOLN2,GYG1,UBE2I,CUTC,PABPC4,ANKRD39,EIF4A3,GOT2,RCSD1,RAD23B,TRA2B,TECR,SPTSSA,RYBP,RBX1,NSUN2,LACTB,WDR82,USP22,ODC1,ARF4,RHEB,CLNS1A,DPYSL3,RPS14,MAP4,BTF3,COPS6,MYL12B,SEPHS2,RPS15,C9orf78,EWSR1,PPP1R12A,SCOC,PPP1R2,CHCHD2,THRAP3,NCKAP1,FAM136A,SLC35B1,PITHD1,NDUFS4,CD59,SUB1,EIF2S2,C4orf3,KIFAP3,TMED2,POLR2I,DCAF8,PTTG1IP,EIF4H,CCT8,SCARB2,CCDC86,QARS,PPP3R1,USP7,ZNF207,BCCIP,KARS,ATXN3,GGNBP2,ASH1L,UGP2,DYNLL1,COPE,TOR1AIP1,STARD7,TM9SF3,EPM2A,PAIP2,TERF2IP,CRKL,ATP6V0B,PSMA6,PARL,CYB5R1,TALDO1,CHTOP,AHCYL1,METTL9,CLCN3,TIMP2,EID1,ATXN1,VDAC1,H2AFV,TAZ,MAT2A,GLOD4,SUPT16H,SOCS7,HIPK2,CHCHD1,RWDD4,RPLP1,TRIM32,TUBB,USP13,CMAS,RAE1,SLC25A12,CAPN2,KIF5B,ADD3,PTEN,AHSA1,FEM1B,SGCB,LDHB,DCAF6,TIMMDC1,ADSL,MRPS10,SH3GLB1,PRDX1,CBX3,PGAM1,VPS29,SNAPIN |
| 6.832e-18 | -39.52 | cellular protein-containing complex assembly | biological process | GO:0034622 | 863 | 226 | 17256 | 2622 |
COX15,NOP2,NDUFB6,UBN1,UQCR10,USP39,TAF6L,SNRPD3,BRIX1,ATPAF1,MIS12,EDC3,RPL23A,SNUPN,DNAAF2,ZNHIT6,XRCC2,RAD23B,DNM2,RPF2,KHDC4,AP2B1,NDUFB9,NUP153,EIF5,SRPK2,SRSF10,COPS8,SNRNP200,SEPT9,RBX1,NCK1,BAZ2A,SNRPB,PSMG1,DDX20,ANLN,MCM2,FOXRED1,LUC7L,CLNS1A,EIF3A,ASF1B,CHAF1A,UBTF,GEMIN5,SEPT1,WAS,MID1IP1,SMAD2,BRD2,TMED10,NIP7,RPS27A,PSMD8,RPS14,LUC7L3,AXIN1,EIF2D,ATXN2L,MIA2,CLU,RRS1,SMAD1,NAA60,SLC25A33,GEMIN7,NDUFV2,RPS15,HJURP,TM9SF4,CENPF,DHX9,DNAAF5,PRPF39,PSMD9,CDC73,NDUFS7,PRPF18,NUP205,MCTS1,NDUFS4,NDUFAF6,FKBP1A,TMEM250,MBD2,XPA,ATP6V0A2,GEMIN4,NSUN4,LUC7L2,TMED2,HP1BP3,DDX28,TSPYL4,RPL6,RPS10,SEPT8,EIF2A,SRSF5,ADRB2,SEPT7,EIF4H,PATL1,SF3A2,BBS12,SEC31A,NAP1L1,GOLGA2,RBMX,SNAP23,PRMT7,CABIN1,RUVBL2,NDE1,RBBP4,ECPAS,UNC13C,ZNF207,SART1,NDC1,NDUFA5,CHMP2A,CORO7,TOMM20,NDUFAF2,SF3B1,XAB2,EIF3D,CHD1L,RAC1,SMARCA4,POMP,EFL1,RPL11,OIP5,RRN3,AHCTF1,SAR1A,PIN1,NUP107,SEPT11,CLTB,STRAP,GPX4,PRPF19,CCT2,DMAC2,CRNKL1,CIRBP,POLR2D,TUBGCP5,RPL38,ATP6V0A1,NDUFA7,PRPF3,NDUFB1,RAB1A,TAZ,TXNL4A,CENPU,RPSA,SRSF1,TAF2,RAD51C,HSPA4,CHMP4A,NDUFA11,H2AFX,ANP32E,XRCC3,SNRPG,H3F3A,AP2S1,SMAD4,CSNK1D,RAD51D,TMEM33,NDUFS1,MZT1,SRSF6,SHPRH,CDT1,AGO2,TIMM21,TUBGCP2,FBXO5,RPA2,FASTKD3,NDUFV1,NDUFA2,NDUFB4,CENPJ,SEC24C,H2AFY,ANP32A,GEMIN6,NDUFS8,CENPM,NAP1L4,PTGES3,ORC3,TTC17,MRPL11,GTF2H2,NDUFA3,YTHDC1,TGFB1,PPAN,COA3,NASP,TIMMDC1,TMEM126B,WDR18,PICALM,DDX23,RPA1,SNAP29,HMGB2,NDUFS5,CENPT,TAF12,TAF6,UBE2C,DDB1,IPO4 |
| 7.199e-18 | -39.47 | heterocycle biosynthetic process | biological process | GO:0018130 | 3095 | 630 | 17256 | 2622 |
ZBTB10,KDM4A,CCNL2,EDRF1,ZNF275,USF1,CIPC,SRSF4,UPRT,CRY2,ECD,ZNRD1,ZNF672,ZNF559,GABPA,MIER2,TOPORS,DIDO1,STOML2,BRMS1,SMAD2,RPS27A,ZNF689,VIPAS39,TFDP2,SMAD1,E2F2,ZNF75A,PFKP,SLC25A33,SSRP1,HIVEP3,DHX9,EZH1,CDC73,MCTS1,TFAP4,INTS7,ZNF326,FOXN2,CPSF4,SRSF11,ETV3,FOXK1,RB1CC1,ZMYND11,MYBL2,USP10,BCLAF1,SRSF5,CBFA2T2,ELK1,POLR2J,ETS2,SETD3,CNOT6,SGF29,ZNF296,KARS,SARNP,TRERF1,IVNS1ABP,PTTG1,RMI2,CREBL2,ZNF267,SLC35B2,INO80E,SAFB2,RCOR3,TCF19,ZNF420,SP100,ZKSCAN1,MTA1,DUT,GMEB1,NABP1,INTS12,ZNF226,ATF2,RPRD1B,CGGBP1,PDCL3,ADCY7,CPNE1,POLR2L,EID1,KAT7,INTS13,WBP2,POLR2D,RNPS1,E2F3,ATP6V0A1,MEF2D,DDX17,TAF2,CHCHD3,HIPK2,PDXK,SNRPG,PPP5C,ZBTB11,COMMD10,GALK1,ZNF786,ZNF445,SRSF6,HABP4,JMJD6,ATP5F1B,WDR5,ETS1,NEXMIF,ZNF92,NEIL2,RPA2,ZBTB45,ERH,SUV39H2,PPP1R8,ZNF260,PRDM4,ZNF710,GTF2H2,MED22,PDPK1,TK1,GUK1,POLK,ZNF512,LDHA,DDX39A,PDE3B,RPA1,ZNF862,ZNF180,KEAP1,POLE,PITX1,LRPPRC,PML,HMGB2,PARP10,USF2,THAP5,COX15,THOC1,GPBP1L1,GNPDA1,RBM8A,CSNK2A1,SND1,BIRC2,PAPOLA,CREM,LIN9,PCNA,GLIS2,ZNF639,INTS1,ETV6,XRCC2,NOC2L,PPCDC,MYBL1,CCAR1,RYBP,SP3,BAZ2A,RAD51AP1,SNRPB,MRPL12,PBRM1,BRCA1,EAF2,USP21,CHD3,E2F4,ZNF367,DVL1,DHFR2,ZNF45,BEND6,FAM208A,NUDT11,POT1,ZNF564,FUBP1,ZCCHC9,PHB2,CENPF,CTCF,CHCHD2,CDK13,RLF,ASXL2,CNOT11,RSAD1,ARID1B,SUB1,RB1,MLX,MED8,MBD2,SSBP3,ZNF746,CTR9,TIMELESS,MDFIC,ICE2,MAML1,ALDH18A1,PREB,LDB1,AMD1,UTP15,RTF1,ZNF761,IRF5,ZNF174,RXRB,MBIP,PALB2,PRPS2,TBPL1,PRMT7,RUVBL2,ATP5F1A,TRAF7,UGP2,SUCLG1,ARID2,FOXM1,DYNLL1,XAB2,ZNF416,RRAGC,COMMD8,ZNF121,NRF1,ZBTB21,ZNF473,KMT5C,ZNF302,RPAP1,TARDBP,SAP30L,ZNF583,DVL2,KDM3B,POLR2G,ZNF780B,BTG2,CPOX,NFATC2,KDM1B,SRSF1,ZNF700,RBL1,MAFK,ZNF436,DNAJC17,XRCC3,NCOA1,SLC25A39,SMAD4,RAD51D,INTS2,SLC30A9,CTDP1,NADSYN1,NIFK,CDC40,MTERF1,AGO2,ARID5A,GTF3A,NKRF,PAGR1,RMI1,WRNIP1,IRF4,SS18L1,PTGES3,POLR1B,RNLS,RBM15B,RPRD1A,HMGN5,ZNF202,ZMYM5,TOP3A,PCGF1,BIRC5,L3MBTL3,TFE3,CDCA7L,BBX,E2F1,IMPDH1,RBPJ,TAF12,NR2F2,PGAM1,HIPK3,IFI16,PPCS,MAX,ZNF496,TXN,CXXC1,NANS,CCNB1,OAT,COMMD6,POLR3K,MYEF2,PA2G4,NOL11,FIZ1,ZNF200,TAF5L,SLC26A2,ZNF800,DNMT1,CDC5L,ZNF524,KLF10,ELOA,AMDHD2,USP22,CBFB,RFC2,PRIM1,IWS1,HHEX,BRD2,DHTKD1,BTF3,ARRB2,CCDC59,HDAC2,PTOV1,COX5B,EWSR1,POLR2K,PRKAA1,RRM1,NOTCH2,PMF1,SUPT7L,ZNF518A,ZNF79,VPS25,NPLOC4,CNOT3,YY1AP1,LHX8,KLF16,ATIC,HDAC7,CTPS1,ATP6V0A2,CYC1,EEF1D,TERF2,PHF10,ZNF84,PRIM2,ELL2,ZNF574,DCTD,ARID1A,PKM,KDM3A,TWISTNB,PHF6,XRCC5,ADSS,ZNF777,SERTAD2,ZFP92,DCK,RBMX,MED15,CEBPG,PIAS2,GPI,YY1,RNF14,NRBP1,NUDT3,ZNF511,ATXN3,ZBTB37,SUZ12,UROD,ADPGK,TERF2IP,SPINDOC,FLAD1,ZNF75D,KDM2A,UCHL5,LPIN2,ADCY9,CDK12,SAP30,BRD4,RFC3,ERF,DRAP1,SLBP,ELP4,EDF1,POLG2,GAR1,TRIM28,CENPU,SUPT16H,PRDM11,VEZF1,RAD51C,ZNF282,HINT1,SAFB,GUCY1B1,STAT1,ATF6,BEND3,EYA2,ATMIN,POLQ,POU3F2,NCOR2,DEPDC1,TWNK,MECP2,TCF3,MYNN,ARGLU1,BLM,SPR,FOXO3,HMG20A,MAD2L2,GTF2F1,WWP2,CCNK,ELP5,CARF,CREB1,CNOT6L,CITED2,NCOA2,TSHZ1,ZFP64,KAT2A,ILF3,RFXANK,ADSL,KLF6,COMMD4,POLR2A,CBX3,ZHX1,ATP5MC3,TFDP1,NAXE,KHSRP,DDX5,TAF6,PURA,RORB,CCNC,POLA2,ADA2,ZNF76,IER2,KMT2E,PHRF1,ZNF107,SIRT2,TAF6L,SNRPD3,COMMD5,MAPK14,ATP5PF,SNAPC4,ZNF696,MBD4,EIF4A3,JAZF1,PHTF1,ZBTB22,TCEA1,OGG1,ARID4A,CARM1,ELOF1,DEAF1,RIOX2,RRM2,SOX4,KMT2C,PRPSAP1,ASF1B,UBTF,PAF1,BRWD1,PQBP1,CRCP,BAZ1B,ZNF268,CHEK2,ZNF768,NACA,MED13L,MEF2A,THRAP3,SRRT,TTF1,DTL,LYAR,NFATC3,ZNF449,MED10,ZNF335,BUD31,YBX1,ACAD8,ZNF189,VOPP1,ATP5IF1,POLR2I,TSTA3,NUDT4,CIC,SLTM,DAPK3,ISG15,UAP1,NFIL3,NUP62,ZFP90,DNPH1,RBBP4,NIPSNAP2,HNRNPDL,ADNP2,ZBTB24,MBD1,TCF12,MMACHC,ASH1L,GNPNAT1,MPHOSPH8,UCK2,SMARCA4,UCK1,PLAGL2,NSD3,IRF3,CHD1,MXD1,MEAF6,SAP130,RRN3,CD3EAP,AKAP8,CHTOP,UTP4,TMEM14C,ZNF770,RLIM,CSTF1,POU2AF1,CGAS,ZNF500,PCGF6,ATXN1,OGDH,MBD3,ZNF317,STAT6,ARNTL,AKNA,BRD9,MAPK1,CBX4,NAT14,DNAJC2,ZNF316,EYA1,SCYL1,KLF13,PAWR,MXD4,HDDC2,GART,KMT5A,NABP2,ANP32A,BRD7,STAT3,AMPD2,SAMD4B,TGFB1,GTF3C6,PSPC1,HELB,MIER1,NADK2,POLR3GL,RCOR1,MEN1,ATP5MF,ZNF407,SYMPK,TFEB,MAPK3,CNOT9,ATAD2,KMT2B,ACAT1,SRSF3,ZMIZ1,TERF1 |
| 7.338e-18 | -39.45 | EWSR1 (EWS RNA binding protein 1) | protein interactions | 2130 | 614 | 183 | 17029 | 2761 |
TXN,PNISR,HNRNPAB,GNPDA1,GPBP1L1,PRKCSH,PHRF1,RBM8A,CUL1,KRR1,USF1,PCNA,NUP210,RAD23B,KHDC4,TRA2B,ECD,TFG,LRRC59,SMARCE1,MRPL57,CDC37,BRCA1,MCM2,CHAF1A,STOML2,GEMIN5,UBTF,EIF4ENIF1,TONSL,RPS27A,PPM1G,PQBP1,KPNA2,COPS6,SMAD1,SMNDC1,HDAC2,ANXA11,PPIB,C9orf78,MAPRE1,EWSR1,PPP1R2,NACA,DHX9,DNAJB1,ITGB5,SRRT,YY1AP1,FBRS,FAM192A,MLX,MED8,SNX18,SSBP3,YBX1,AHCY,MAML1,NSUN4,SRSF11,EIF5A,ETV3,PRRC2A,CIC,RPS10,MYBL2,C1orf35,GORASP2,ARID1A,SRSF5,PKM,ELK1,EIF4H,ZDHHC3,MATR3,XRCC5,CAND1,MBIP,PCM1,ETS2,CDCA5,MED15,YWHAZ,HNRNPDL,RNF114,USP7,ZNF207,NDUFA5,ATXN3,SARNP,RPLP2,CHERP,FAM207A,SUZ12,SUMO2,OLA1,IRF3,PCBP1,GLRX3,RAD23A,CCDC50,AKAP8,TALDO1,PDIA6,CDK12,RPRD1B,ARHGAP17,RPL29,POLR2G,HMGN4,CUL3,GLO1,CDCA2,EDF1,VDAC1,NDUFB1,MBD3,H2AFV,PEF1,ERC1,PDHX,FKBP3,RPSA,SRSF1,SUPT16H,DDX17,KIF2A,HINT1,DGCR8,SAFB,STK38,NSMCE2,PROSER1,CEP55,ANP32E,FUS,SMAD4,ANXA6,RRP15,SRSF6,CDCA8,ARFIP2,ARGLU1,SDF2L1,SPDL1,HDGFL2,WWP2,RPA2,NDUFV1,DNAJC8,CTNNBL1,SUV39H2,SEC24C,AHSA1,RRBP1,COPS7B,PTGES3,UBE2M,TMX1,SPTAN1,LDHB,RPRD1A,RPL8,API5,PICALM,SNRPA,POLR2A,RPA1,MYO1F,UPF1,C1orf131,MFAP1,SNAP29,TFE3,HNRNPH3,PITX1,ACAT1,ZRANB2,SRSF3,IGBP1,CD81,DDB1 |
| 8.471e-18 | -39.31 | REACTOME_CELL_CYCLE_MITOTIC | MSigDB lists | REACTOME_CELL_CYCLE_MITOTIC | 301 | 105 | 17377 | 2626 |
POLA2,FGFR1OP,MAX,DYNLL1,PTTG1,CUL1,NUF2,KIF2C,ORC1,CCNB1,PRKACA,MIS12,LIN9,CDKN2C,PCNA,PSMD1,AHCTF1,PSMA6,CCNA2,NUP107,CDKN1B,ANAPC7,CDC25B,CEP63,SEH1L,DCTN1,PLK1,RFC3,PSMA8,TAOK1,E2F3,PSMB7,TUBGCP5,RRM2,CDC6,AURKB,PKMYT1,CDC23,MCM2,RFC2,PSMB9,GINS4,PRIM1,KIF2A,PPP2CA,CDC16,PPP2R5A,DSN1,RBL1,RPS27A,PSMD8,E2F4,PSMD3,E2F2,PSMC1,CSNK1D,TUBB,MCM10,MAPRE1,GORASP1,CDT1,DCTN2,DBF4,CDCA8,KIF23,PMF1,PSMD9,TUBGCP2,HAUS2,FBXO5,RPA2,RB1,PSMD2,SMC3,CENPJ,MCM5,KNTC1,CENPM,ORC3,NUP85,NUDC,GINS1,PRIM2,MYBL2,PSMA1,ANAPC2,RANGAP1,PSMB3,PSMC4,RPA1,KIF18A,PCM1,POLE,CDC27,BIRC5,TFDP1,E2F1,SSNA1,CENPT,RBBP4,CDK2,UBE2C,CCNB2,ANAPC4,CDKN2A |
| 8.940e-18 | -39.26 | spliceosomal complex | cellular component | GO:0005681 | 188 | 76 | 18223 | 2701 |
SART1,IVNS1ABP,XAB2,SF3B1,RBM8A,DHX8,USP39,SNRPD3,SF3B2,HNRNPA2B1,NSRP1,EIF4A3,GPATCH1,KHDC4,TRA2B,AQR,PRPF19,CDC5L,SNRNP200,SNRPB,PPIE,SMU1,CRNKL1,HNRNPF,LSM8,SREK1,PRPF3,TXNL4A,LUC7L,RHEB,DHX15,SRSF1,SUGP1,DHX16,LSM6,HNRNPR,LUC7L3,PRPF4,SNRPG,SMNDC1,PRPF4B,PRPF38B,CDC40,LIME1,ZCCHC8,PRPF39,PDCD7,PRPF18,RBM17,SNRNP25,CTNNBL1,CWC27,PPP1R8,EFTUD2,ZNF326,BUD31,YBX1,PABPC1,HNRNPM,LUC7L2,SF3B6,PPWD1,API5,DDX39A,SF3A2,SNRPA,DDX23,UPF1,SYNCRIP,RBM25,HNRNPH3,RBMX,DDX5,SNRNP70,ZNF830,WDR62 |
| 9.613e-18 | -39.18 | GO_TRANSFERASE_COMPLEX | MSigDB lists | GO_TRANSFERASE_COMPLEX | 662 | 184 | 17377 | 2626 |
MIB2,POLA2,CCNC,MAX,CXXC1,CUL1,TAF6L,CCNL2,SNRPD3,UBE2I,BECN1,POLR3K,ZER1,ATG3,METTL14,INTS1,PIK3R2,TAF5L,SPTSSA,ZNRD1,USP34,METTL1,ERCC1,DPM1,RBX1,VHL,SNRPB,WDR82,TOPORS,UBE2V1,BRCA1,DCUN1D5,USP22,CCNF,KRTCAP2,PRPSAP1,CLNS1A,PAF1,RAD18,STT3A,OGT,DHTKD1,CRCP,CAB39,ACTB,FBXL3,DCAF5,HDAC2,POLR2K,ZNF768,PRKAA1,KCTD17,CDK13,EZH1,SUPT7L,METTL3,CDC73,DTL,RB1,RPN1,MED10,KLHL5,INTS7,DAD1,FBXO7,ZNF335,CTR9,FBXL7,PHKG2,POLR2I,RB1CC1,DCAF8,TEX10,RTF1,UBE4B,SYVN1,TWISTNB,CAND1,MBIP,FNTA,CDC27,POLR2J,KLHL15,DCAF11,TBPL1,PTAR1,RUVBL2,NAA20,RBBP4,MAP3K5,CDK2,RNF14,PDSS2,BCCIP,PRKAB1,TRAF7,SUZ12,UBR2,KLHL18,PRKACA,ANKIB1,MEAF6,PHC2,SAP130,BRPF3,CD3EAP,CDKN1B,INTS12,RPN2,ANAPC7,RNF19A,NAA35,RPRD1B,CDK12,POLR2L,POLR2G,PGGT1B,KAT7,CUL3,POLR2D,PCGF6,ELP4,EDF1,OGDH,DNAJA1,CDC23,ERC1,MAT2A,TAF2,CDC16,DDOST,STK38,SEL1L,SNRPG,CBX4,INTS2,CTDP1,KLHL21,TRMT6,BRAP,CBLL1,SDF2L1,UBE4A,WDR5,DCUN1D4,MAD2L2,GTF2F1,WWP2,MAT2B,CCNK,ERH,KLHL20,PRDM4,NAA50,H2AFY,ATG13,POLR1B,OSTC,FBXL19,GTF2H2,RPRD1A,DCAF6,KAT2A,HELB,PRKAR1B,POLR3GL,FBXO9,ANAPC2,MEN1,POLR2A,HSPA1B,FBXO21,KEAP1,MAGT1,POLE,GOLGA7,PRDX3,KBTBD7,SPCS3,TAF12,UBE2C,TAF6,DDB1,ANAPC4 |
| 1.080e-17 | -39.07 | MORF_FBL | MSigDB lists | MORF_FBL | 131 | 61 | 17377 | 2626 |
KARS,MRPL9,TOMM20,H2AFZ,HNRNPAB,PHB2,PDAP1,SUMO2,STARD7,CYCS,UBE2I,PARK7,RAD23A,HNRNPA2B1,NDUFV1,PCNA,BANF1,CS,YBX1,TARDBP,AHCY,CYC1,PTGES3,FBL,CCT2,HMGN1,POLR2I,CDC123,SNRPB,RPL6,VDAC2,TUFM,RNPS1,JTB,ILF3,PSMB7,AURKB,TMEM147,MCM2,EIF4H,TRIM28,SF3A2,EIF3G,SNRPA,CLNS1A,CBX3,EIF3K,NAP1L1,DDOST,PSMD8,RBMX,TBL3,PPM1G,UQCRH,GPI,BTF3,RUVBL2,SRSF3,FAU,IDH3B,RBBP4 |
| 1.122e-17 | -39.03 | organelle membrane | cellular component | GO:0031090 | 2910 | 586 | 18223 | 2701 |
RAB14,TMED7,MRPS15,ABCC10,TGOLN2,SYNRG,CMTM6,NAPG,AP1M1,DNM2,NUP153,LRRC59,RHBDD2,MGAT5,SENP1,KCNAB2,MRPL57,BAK1,PGAP2,RHOBTB3,TMEM115,NRAS,MRPL43,MCL1,NUTF2,SLC50A1,RAB22A,PLEKHF2,STOML2,AHNAK,WDR11,RPS27A,MYO18A,MPV17,COX5A,ATP6V0C,ST3GAL2,SMAD1,CHPF2,AAAS,SLC25A33,NDUFV2,MRPL9,MRPS2,GGA1,CCZ1,RAB23,TMED3,COPB2,LMNA,TMEM179B,CD59,TNPO3,MRPL21,NUP85,PPP6R1,NAGPA,TIMM8B,RB1CC1,PGS1,MAN1B1,GTPBP4,MRPL16,MTX1,SFXN5,MATR3,RHOB,CYB5A,SCARB2,OSBPL11,SNX14,NUP58,MRPL3,EXOC3,RHOG,ANKRD27,ABCA3,TMEM97,VTI1A,STARD7,RXYLT1,SLC35B2,STAM,APP,CPNE3,RAB21,AHCTF1,ATP2A2,UTP18,NUP107,CLCN6,MICU2,MAVS,ATF2,RBM15,TMEM9,GCC1,ATP6V1G1,CPNE1,ENPP4,SNX8,SEC61B,GOPC,ATP6V0A1,NDUFA7,RAB1A,TAZ,CHCHD3,ALDH3B1,PEX5,TICAM1,ANXA6,TMBIM4,FLOT1,ATP5F1B,SLC25A43,CLIC4,PDCD10,COQ4,NDUFB4,ST8SIA2,TPCN1,MFSD12,MOB4,MRS2,MRPS10,PICALM,MAGT1,WNT5B,ACOX1,LRPPRC,PML,SLC25A19,AEN,PSAP,YWHAH,SNAPIN,COX15,SNX15,CDIPT,SEC16A,RUFY1,PRNP,RAB8A,NUP210,TIMM23,INTS1,SLC44A1,ZFYVE27,MRPL32,MIOS,APH1A,MRPL12,CYSTM1,STX16,RAB5B,RHEB,OPTN,NECAP2,TIMM13,AGPAT2,GRIPAP1,NRM,PIEZO1,DHFR2,CLN3,NAA60,C2CD5,NEMP2,PHB2,DNAJB2,LAMTOR3,COX4I1,RAB6A,B4GALT4,C1GALT1,MLX,TIGAR,VMP1,ARL6IP1,MRPL48,GLE1,TMEM8A,ALDH18A1,ABCC1,PREB,CYTH1,TRAPPC9,ACSL3,NPIPA1,APPL1,ZDHHC3,RMC1,SDHB,GOLGA4,GALNT2,PCM1,SNAP23,LAMTOR4,COX7A2L,ZDHHC7,ATP5F1A,UNC13C,NDUFA5,NDUFAF2,MRPL39,DYNLL1,TOR1AIP1,SLC2A1,COPE,RRAGC,ZFYVE21,ATP6V1B2,LYN,BCAP31,MRPL50,SEC11A,ATP6V0B,MDM2,WDR44,MRPL34,CORO1A,LMAN1,SNX25,PPIF,CLCN3,COQ10B,RAB7A,CPOX,SLC26A6,NUP155,VDAC1,CHMP2B,TXNL4A,MRPS14,TMEM201,MRPL2,SCAP,TIMM17A,TOMM6,NDUFA11,AP1S1,CHMP4B,AP2S1,SLC25A39,ZC3HC1,INTS2,GOLIM4,TMX3,ARFIP2,ARF1,GGA2,AP3S1,SCYL2,TFRC,FZD6,NDUFV1,SLC35B4,ABCD1,RNF5,CAMK2G,ACP2,RHOA,MLEC,SNX2,RANGAP1,PNPLA8,RHOT2,CHCHD6,NEU1,RAB18,KPNA4,SEC23IP,ATP6V1D,PDCD6,GOLGA7,SNAP29,PGRMC1,GLG1,PKD2,ACADM,SPCS3,CHMP7,NDUFB6,ADAM10,ZDHHC8,TAP1,TMEM109,AP3M2,PARK7,RIC1,SLC25A37,GLMP,ASAP2,DBNDD1,RAB4A,TRA2B,AP2B1,CISD2,MARCH2,TFG,SEH1L,USO1,ATG9A,GALNT7,SLC17A5,MCFD2,SLC25A5,FOXRED1,RAB2B,WAS,TMED10,MRPL27,UQCRH,RTN3,B4GALT2,SVIP,COX5B,DNAJC5,SCOC,HLA-E,ACAP1,B4GALT1,NDUFA4,CYCS,PXMP2,MAN2B1,SLC35B1,NOTCH2,TMEM165,PSEN1,COPG2,VPS25,NDUFS7,NDUFS4,NDUFAF6,FKBP1A,RNF121,SNX18,ZNRF2,BDH1,SLC25A51,TPST1,ATP6V0A2,MRPL40,CYC1,PIKFYVE,TNRC18,LPCAT1,TMED2,COQ8A,SIGMAR1,NOA1,RDH10,MFNG,USF3,GORASP2,ADRB2,TOMM40,GOSR1,MAP2K2,AKAP1,PI4K2A,DERL1,SEC31A,CAT,GOLGA2,NSF,ERGIC3,APPL2,ARAP1,SAMD8,SMPD4,PPP6R3,NDC1,ATXN3,SYS1,RAB11B,RAF1,GPR89A,RAC1,SLC39A13,POMP,BCL2L1,AP1B1,SLC25A44,SNN,SDHA,GNB2,CD320,MOAP1,APLP2,MTMR4,MRPS27,BRI3,TNPO2,TAP2,TMBIM1,CUL3,VDAC2,PKMYT1,AP4E1,ERC1,ANKZF1,CHMP4A,MRPL55,DDOST,CERS6,RAB24,GOLGA8A,ATF6,B4GALT3,CSNK1D,NDUFS1,MANBA,B4GALT5,BRAP,SLC25A12,AGPAT3,FOXO3,RAB11A,HLA-A,PIP5K1C,SLC25A36,NDUFA2,CRAT,FUT8,MRPL54,NDUFA3,MTX2,TMEM126B,DENND4C,KCNQ1,RHOT1,GUF1,SPPL2B,SH3GLB1,CBX3,YIF1A,NUCB1,HGS,ATP5MC3,CCZ1B,STX18,NDUFS5,WDR91,IPO4,VPS29,HIGD2A,GPR89B,MTX3,COPA,UQCR10,ABCB10,BECN1,ATP5PF,MAP1LC3B,MRPL19,PCYOX1L,RAP1A,CDC42,GOT2,AP3S2,RAB35,SRI,HADHB,NDUFB9,SLC35C2,TRIM14,DRAM2,TIMM50,WDR41,NCK1,SLC25A22,PITPNB,MPC1,MAN2A2,TIMM29,ROCK1,GALNT10,VPS4A,CLU,CHPT1,MRPL13,RPS26,ATP6V0E1,STARD3NL,UBE2D3,AGTRAP,GORASP1,CDIP1,PCSK7,QSOX2,NUP205,DTL,EI24,YBX1,BCL2,ATP6V0D1,KDELR1,VOPP1,ATP5IF1,GBA,EVC2,NSMF,NUP62,CTSA,YWHAZ,EHD4,TMEM14A,NIPSNAP2,CHMP2A,SNX27,IMMT,TOMM20,CORO7,GNPNAT1,CHERP,EXT2,MIEF1,ANKRD28,ANKLE1,SAR1A,PPP6C,PARL,RPN2,CYB5R1,APOOL,CLTB,TMEM14C,HTRA2,CHP1,MOSPD1,EBAG9,ACSL5,DMAC2,TOR1AIP2,OGDH,ERBIN,NDUFB1,PEF1,DAP3,SURF4,TAB2,CHCHD1,STAT6,WDR59,CANT1,SCARB1,DNAJC2,CDS2,GOLPH3L,MRPL42,SCYL1,NUP54,MRPS26,VPS45,TIMM21,LETMD1,MFSD10,MAN1A1,SPPL2A,SEC24C,ZDHHC13,YIF1B,NDUFS8,MRPL11,STAT3,SLC35A1,SLC25A1,B3GALT6,COA3,TIMMDC1,ATP2C1,COG1,RFFL,WDR81,ATP5MF,MFN2,LEMD2,HLA-B,OSBPL8,COX8A,ATP6V1C1,PLOD3,HRAS |
| 1.293e-17 | -38.89 | GSE22886_NEUTROPHIL_VS_MONOCYTE_DN | MSigDB lists | GSE22886_NEUTROPHIL_VS_MONOCYTE_DN | 186 | 76 | 17377 | 2626 |
KARS,IMMT,TOMM20,EIF3D,UROD,YTHDC2,SNRPD3,KTN1,PARK7,RPL11,HNRNPA2B1,UTP18,TRA2B,TTC3,AQR,METTL9,DNMT1,STRAP,KLF10,POLR2L,SLC16A7,VDAC2,UTP3,TMEM147,DHX15,MAT2A,EIF3A,RPL37,AHNAK,TIMM13,WDR11,RPS27A,CERS6,TIMM17A,PSMD3,COX5A,UQCRH,RECQL,NDUFS1,UFC1,NDUFA4,SUPT7L,PDXDC1,NPLOC4,NDUFS4,CAPN2,GNS,PTPN2,TNS3,LRRC8D,BANF1,YBX1,RBM3,MDFIC,CYC1,NUP85,NAGPA,EIF3L,PSMA1,RPS24,DDX39A,CCT8,SEC31A,EPRS,NAP1L1,SGSH,SYNCRIP,DUSP3,QARS,NUP62,RUVBL2,SRSF3,IDH3B,PLOD3,HEXA,MRPL3 |
| 1.380e-17 | -38.82 | GO_CELLULAR_MACROMOLECULAR_COMPLEX_ASSEMBLY | MSigDB lists | GO_CELLULAR_MACROMOLECULAR_COMPLEX_ASSEMBLY | 669 | 185 | 17377 | 2626 |
COX15,NDUFB6,UBN1,UQCR10,USP39,SNRPD3,BRIX1,ATPAF1,MIS12,EDC3,RPL23A,SNUPN,DNAAF2,ZNHIT6,XRCC2,RAD23B,AP2B1,RPF2,NDUFB9,NUP153,SRSF10,SRPK2,SNRNP200,NCK1,RBX1,SNRPB,PSMG1,DDX20,ANLN,MCM2,LUC7L,FOXRED1,ASF1B,EIF3A,CLNS1A,CHAF1A,GEMIN5,MID1IP1,SMAD2,WAS,BRD2,TMED10,NIP7,RPS27A,PSMD8,RPS14,LUC7L3,AXIN1,EIF2D,ATXN2L,CLU,SMAD1,NAA60,SLC25A33,GEMIN7,RPS15,NDUFV2,HJURP,CENPF,PRPF39,PSMD9,PRPF18,NUP205,NDUFS7,NDUFS4,MCTS1,FKBP1A,MBD2,XPA,ATP6V0A2,GEMIN4,NSUN4,LUC7L2,TMED2,HP1BP3,EIF3L,DDX28,TSPYL4,RPS10,RPL6,ADRB2,EIF2A,SRSF5,EIF4H,PATL1,SF3A2,BBS12,CAND1,NAP1L1,GOLGA2,SNAP23,PRMT7,CABIN1,RBBP4,NDE1,ZNF207,CHMP2A,NDUFA5,SART1,CORO7,TOMM20,NDUFAF2,XAB2,SF3B1,EIF3D,CHD1L,RAC1,POMP,RPL11,OIP5,AHCTF1,NUP107,TNPO2,STRAP,PRPF19,CCT2,CDC123,POLR2D,TUBGCP5,CRNKL1,CIRBP,RPL38,ATP6V0A1,PRPF3,NDUFA7,NDUFB1,RAB1A,TXNL4A,TAZ,EIF3G,RPSA,EIF3H,SRSF1,TAF2,EIF3K,RAD51C,CHMP4A,HSPA4,NDUFA11,H2AFX,XRCC3,SNRPG,H3F3A,AP2S1,SMAD4,CSNK1D,RAD51D,TMEM33,CDC40,NDUFS1,SHPRH,SRSF6,TUBGCP2,FBXO5,RPA2,NDUFV1,NDUFA2,NDUFB4,CENPJ,GEMIN6,H2AFY,NDUFS8,CENPM,NAP1L4,TTC17,MRPL11,GTF2H2,NDUFA3,TGFB1,PPAN,YTHDC1,NASP,TIMMDC1,TMEM126B,BMS1,PICALM,RPA1,DDX23,SNAP29,HMGB2,CENPT,NDUFS5,UBE2C,DDB1,IPO4 |
| 1.481e-17 | -38.75 | mitochondrion | cellular component | GO:0005739 | 1564 | 352 | 18223 | 2701 |
NDUFB6,MRPS15,ZDHHC8,GLUD1,LACTB2,CCNB1,OAT,PARK7,SLC25A37,C14orf119,NAPG,MTFR1L,MECR,DNM2,SUCLG2,CISD2,LRRC59,MRPL57,BAK1,HSDL1,MRPL43,LACTB,MCL1,COA7,SLC25A5,FOXRED1,STOML2,BOLA3,RPS27A,MRPL27,PRDX5,OGT,MPV17,COX5A,MLYCD,DHTKD1,UQCRH,RNASEL,TFDP2,SLC25A33,NDUFV2,COX5B,MRPL9,DNAJC5,MUT,MRPS2,ADO,NDUFA4,PXMP2,CYCS,PSEN1,NDUFS7,NDUFS4,C12orf10,NDUFAF6,TFAP4,FBXO7,BDH1,SLC25A51,MRPL40,CYC1,PIKFYVE,MRPL21,TNRC18,MRM3,NSUN4,CARS2,TIMM8B,DDX28,COQ8A,DHX29,NOA1,PGS1,MTFR2,MRPL16,MTX1,PKM,MPG,ELK1,TOMM40,SFXN5,MAP2K2,CYB5A,AKAP1,FAS,PI4K2A,CAT,MTHFD2,QARS,PPP3R1,MDH1,ACSF2,MRPL3,FAM72A,KARS,ATXN3,RAF1,STARD7,BCL2L1,SLC25A44,SNN,PRKACA,CPNE3,SDHA,MOAP1,FLAD1,DECR1,SHC1,GRSF1,UCHL5,DUT,MRPS27,MICU2,MAVS,TP53BP2,ATF2,MRM2,GPX4,IDH3A,LYRM1,VDAC2,ABHD11,NDUFA7,DNAJA1,TAZ,POLG2,DHX57,PPP2CA,CHCHD3,ANKZF1,RAD51C,MRPL55,PPA2,PITRM1,EYA2,NDUFS1,ANXA6,TWNK,MECP2,CCM2,TRAK1,SLC25A12,ARGLU1,SECISBP2,ATP5F1B,SLC25A43,FOXO3,SLC25A36,CLIC4,NDUFA2,GATC,COQ4,NDUFB4,PTEN,CRAT,PTPN11,MRPL54,CREB1,NDUFA3,MTX2,PACS2,PPP3CA,ANKRD37,TMEM126B,MRS2,JTB,ILF3,MRPS10,TBRG4,HEBP2,RHOT1,GUF1,MARK2,ECH1,SH3GLB1,SH3BP5,GPS2,ATP5MC3,PFDN4,PRDX3,PARG,TFDP1,LRPPRC,NAXE,SLC25A19,NDUFS5,YWHAH,HIGD2A,COX15,LYRM4,MTX3,UQCR10,MCCC1,ABCB10,SIRT2,USP48,BECN1,MAPK14,ATP5PF,MAP1LC3B,MRPL19,ATPAF1,BCAT2,GOT2,TIMM23,TRMU,SLC44A1,HADHB,SRI,NDUFB9,NFU1,OGG1,TRIM14,MRPL32,TIMM50,HARS,VHL,MRPL12,SLC25A22,SOX4,MPC1,TIMM13,TIMM29,IARS2,QRSL1,STK11,DHFR2,CLU,CLN3,OSGEPL1,MRPL13,CAPN1,HJURP,PHB2,CHCHD2,COX4I1,XPNPEP3,RGS2,RSAD1,RHBDD1,APOPT1,TIGAR,PYURF,BCL2,MRPL48,ALDH18A1,ACAD8,NIPSNAP1,ATP5IF1,DCAF8,OXR1,ACSL3,KRAS,SDHB,COX7A2L,YWHAZ,ATP5F1A,NIPSNAP2,TMEM14A,PDSS2,NDUFA5,TOMM20,IMMT,SUCLG1,IFI27L1,NDUFAF2,MDH2,DYNLL1,MRPL39,LYN,BCAP31,MXD1,MIEF1,MRPL50,PDK2,CD3EAP,PIN1,AKAP8,PPP6C,CS,MRPL34,PARL,CYB5R1,TOP1MT,APOOL,TMEM14C,HTRA2,PPIF,ACSL5,COQ10B,CPOX,DMAC2,NLN,BOLA1,OGDH,NDUFB1,VDAC1,MRPS14,GFER,PDHX,GLOD4,PON2,MRPL2,DAP3,IDE,CHCHD1,TOMM6,TIMM17A,FASTK,NDUFA11,XRCC3,SMURF1,MAPK1,SLC25A39,PDF,CDS2,MRPL42,MTERF1,MRPS26,LETMD1,TIMM21,GFM2,GTPBP3,FASTKD3,GSTK1,NDUFV1,NDUFS8,ATG13,MRPL11,STAT3,RNF5,SLC25A1,COA3,HEMK1,TIMMDC1,ABCF2,TUFM,NADK2,WDR81,ATP5MF,HAGH,RHOT2,CHCHD6,MAPK3,HSPA1B,MFN2,COX8A,E2F1,ACAT1,ACADM,IDH3B,GCSH |
| 1.635e-17 | -38.65 | catalytic activity | molecular function | GO:0003824 | 5888 | 1097 | 17224 | 2647 |
ABCC10,HEXB,LACTB2,FBXO22,EEF2K,ATP13A3,MECR,DNM2,UPRT,CRY2,RNF26,ZNRD1,TIPARP,FTSJ3,MGAT5,RHBDD2,USP34,ERCC1,RHOBTB3,NRAS,EHMT1,KIF15,MIER2,MCM2,RAB22A,ARF4,GINS4,RAD18,MYO18A,OGT,COX5A,RNASEL,KLHL42,CHPF2,ZNF720,RHOC,TRIO,DHX9,RAB23,EIF2AK4,PARN,APH1B,MYL6B,ATG4A,PDXP,SMC3,RNFT1,EFTUD2,FBXO7,CPSF4,PHKG2,NSUN4,PPA1,MAPKAPK3,MTA2,TYW1,ERO1A,GTPBP4,USP10,EIF4H,RDH11,FNTA,TYW5,ACSF2,RHOG,TRIM41,KARS,NQO1,GLRX3,LCLAT1,CPNE3,ABHD16A,FBXL6,MTA1,UBA5,SEPT11,GPD1L,ZC3H3,PDCL3,CPNE1,ULK3,ERMP1,POLR2L,KAT7,IDH3A,POLR2D,HTATIP2,PFKFB3,RAB1A,MAT2A,KIF2A,PPP2CA,ALDH3B1,NSMCE2,CAMKMT,RNF38,PPP5C,PITRM1,TUBB,USP13,ZFP91,ABHD14B,IP6K2,ATP5F1B,WDR5,IFT27,PMVK,NEXMIF,NEIL2,TUT4,SRXN1,PPP1R3B,PSMD2,CLIC4,HUWE1,ARF5,NAA50,LTN1,KANSL2,UBE3B,ST8SIA2,FBXL19,GTF2H2,DDX24,USP42,LDHA,MAGT1,PARG,ACOX1,AEN,PARP10,TRIM11,YTHDC2,SND1,PAPOLA,ZER1,TET3,FANCL,RAB8A,NT5DC1,POP7,EIF5,PLK1,RPP25,PTPN18,SEPT9,RBX1,APH1A,MBLAC2,UBE2V1,PBRM1,ODC1,USP21,LSG1,ALG3,TRIM4,AGPAT2,CHD3,ADAM9,NGLY1,CTU2,RMND5A,PARP12,KLC1,COX4I1,CDK13,ADCK5,RAB6A,RSAD1,C1GALT1,UBE2Q2,KIF13B,AHCY,LRSAM1,HDHD2,NTPCR,ABHD2,NSDHL,ACSL3,AMD1,MAP4K3,METTL22,STYXL1,NMT2,SDHB,MBIP,GALNT2,COX7A2L,ZDHHC7,DTD1,RUVBL2,MYO9A,CCNB2,USP7,GLT8D1,SUCLG1,TRAF7,NDUFAF2,TMX4,ZFYVE21,RRAGC,ATP6V1B2,LYN,VAV1,PSMA6,KMT5C,PPME1,PIN1,RPAP1,AHCYL1,TOP1MT,CTDSP2,SPSB3,PRPF19,PPIF,KDM3B,BIRC3,POLR2G,PPT1,RAB7A,PPIE,DCLRE1C,RHBDF2,IDE,DHX16,STK38,FASTK,UHRF2,XRCC3,CHID1,RAD51D,CMAS,NADSYN1,KLHL21,AGO2,TMX3,ARF1,CDK11B,SCYL2,HERC3,GTPBP3,CTSS,POLR1B,RNLS,RNF5,ACP2,RHOA,PRKDC,BTAF1,METTL5,ABCF2,TUFM,TOP3A,PNPLA8,HAGH,DDX23,RAB18,SEC23IP,NEK1,TRIM26,PDCD6,ATP6V1D,NEIL3,CTBS,IMPDH1,USP20,RBPJ,TAF12,PGAM1,HIPK3,TXN,GXYLT1,ADAM10,CXXC1,USP39,CUL1,NANS,GYG1,UBE2I,OAT,PARK7,ASPHD2,RAB4A,FBXW2,SUCLG2,TAF5L,MARCH2,SMARCE1,NSUN2,LACTB,USP22,RFC2,RAB2B,PRIM1,DOT1L,MAP3K4,MKNK1,KIF18B,TPP2,PTPDC1,B4GALT2,RECQL,COX5B,DHPS,POLR2K,GSPT2,PRKAA1,TATDN3,RRM1,B4GALT1,CYCS,SUPT7L,PSEN1,PDXDC1,NDUFS7,WDR48,TMEM250,RPN1,EXOSC7,KLHL5,ZNRF2,PPP4R1,MSH2,PIGG,TPST1,DAPK1,FBXL7,CYC1,MRM3,FDFT1,PRIM2,PIGT,CPQ,COQ8A,RDH10,USF3,MFNG,EXOSC9,MTR,CCT8,MAP2K2,TWISTNB,PI4K2A,XRCC5,CAT,MTHFD2,USP32,PIAS2,SAMD8,SMPD4,GPI,NUDT3,ATXN3,TP53RK,RAB11B,RAF1,UROD,NUDT19,DECR1,CCNA2,SIAH1,MTMR4,RALB,ADCY9,LPIN2,TAP2,TTC3,RNASEH2A,AQR,CDK12,ILKAP,SAP30,NARF,ELP4,ABHD11,EDF1,PKMYT1,TRIM28,AMZ2,ANKZF1,RAD51C,HINT1,DDOST,CERS6,DGCR8,RAB24,HAGHL,FTSJ1,XRCC4,EYA2,DYNC1LI2,ADAM23,PRPF4B,NDUFS1,MANBA,B4GALT5,TKT,CBLL1,LANCL1,POFUT1,EBP,WWP2,CCNK,RFWD3,NDUFA2,FUT8,PTPN11,FEM1B,NDUFA3,MSH6,KAT2A,LONRF3,ADSL,FBXO9,BMS1,OTUD3,GUF1,ARSK,KIF11,MACF1,SPPL2B,MYO1F,LTBP4,PPP1R11,DUSP11,DDX5,NDUFS5,ESPL1,CCNC,POLA2,NAT9,PIGM,KMT2E,UQCR10,HMGXB3,PTP4A3,UBE2Q1,ABCB10,ATP5PF,PCYOX1L,CDC42,GOT2,RAB35,HADHB,CARM1,SRPK2,LARS,SNRNP200,LAP3,VHL,RIOX2,ARHGDIB,KMT2C,PRPSAP1,MAN2A2,PPM1G,BAZ1B,CRCP,CAB39,STK11,CHEK2,VPS4A,CLU,CHPT1,ATP6V0E1,CAPN1,UBE2D3,PCSK7,PM20D2,XPNPEP3,QSOX2,PRPF18,CHKA,DTL,MED10,ZRANB1,ATP6V0D1,CSNK1G3,ATP5IF1,POLR2I,NUDT4,GBA,SYVN1,VKORC1,DAPK3,MASTL,UAP1,KLHL15,SIAH2,FN3KRP,CTSA,DNPH1,TSEN15,PRKAB1,MDH2,PMS2,UCK2,UCK1,SMARCA4,EXT2,USP5,IARS,CD3EAP,KIF14,EXOSC1,PPP6C,CS,CYB5R1,DNAL4,PGGT1B,HPDL,RNF25,METTL2A,GLO1,OGDH,EDEM2,MBD3,PDHX,ALKBH6,PON2,DUS3L,FKBP5,MAPK1,ABCA1,PDF,NAT14,GCLM,TRIP12,SHPRH,DCTN2,SCYL1,MYO9B,PIP4K2A,GFM2,SPPL2A,FASTKD3,KIF5B,FGFR3,KLHL20,GRK2,PPIG,KMT5A,ZDHHC13,DUS2,NDUFS8,FBL,ERI3,MYO5A,MICAL3,B3GALT6,AMPD2,TXNL1,ELOVL5,HEMK1,HELB,MIER1,ATP2C1,NADK2,RFFL,RCOR1,PRMT2,CDK11A,CTSL,MTMR3,UPF1,DTX4,KMT2B,ACAT1,PLOD3,TERF1,HRAS,RAB14,FGFR1OP,MAP3K7CL,KDM4A,PIGQ,AGPAT1,XIAP,DHX8,GLUD1,CDK5,PSMD1,NEK6,SENP1,KCNAB2,PLK3,TOPORS,ICMT,BRMS1,LIMK1,PRDX5,MLYCD,ATE1,ATP6V0C,ST3GAL2,FBXL3,LONP2,PFKP,DDX42,NDUFV2,CERK,TOP2B,ZNRF3,EZH1,GNS,DDX56,INPP5A,MCM5,RTCB,CARS2,UBE2QL1,NAGPA,PGS1,DHX29,MAN1B1,ARMT1,MPG,ABCF1,CYB5A,RHOB,PTPRF,POLR2J,CSK,DUSP3,TEX30,SETD3,PTAR1,CNOT6,MDH1,PLPP6,HEXA,RNF139,EGLN1,ABCA3,UBR2,CHD1L,MYH9,RXYLT1,NIT2,EFL1,PRKACA,ANKIB1,PRKD3,RAB21,ATP2A2,DUT,RNF19A,ATF2,RNF169,ADCY7,ATP6V1G1,DCTN1,ENPP4,MAP4K4,ATP6V0A1,NDUFA7,TAZ,FKBP3,DDX17,HIPK2,NT5C3B,MBOAT1,PDXK,GEN1,GALK1,JMJD6,UBE4A,PLPP5,FBXO3,CAPN2,SUV39H2,GATC,NDUFB4,PPP1R8,PRDM4,DCP1A,TMX1,LYPLA2,IMPA2,LDHB,PDPK1,PPP3CA,NUDT8,TK1,GUK1,TNFAIP3,GALC,POLK,PDE3B,DDX39A,ZNF862,KEAP1,KIF18A,POLE,TATDN2,CAPN7,MAPK6,LRPPRC,PSAP,ANAPC4,SRM,COX15,DDX47,GNPDA1,MCCC1,CSNK2A1,CDIPT,BIRC2,KCMF1,ABL2,PCNA,PIK3R2,XRCC2,TRMU,PPCDC,FAM86C1,PTPRK,CDC37,ABCC5,METTL1,EXOSC6,HARS,TLK1,BRCA1,RAB5B,RHEB,DPYSL3,SEPT1,NAGLU,QRSL1,DHFR2,OSGEPL1,NUDT11,NAA60,SEPHS2,ASAH1,PPP3CB,B4GALT4,NUS1,TIGAR,CMTR2,PPIL2,SLC27A4,ALDH18A1,TMEM8A,ABCC1,NQO2,AACS,EIF2AK1,KRAS,UBE4B,ZDHHC3,PSMC4,PRPS2,PRMT7,ATP5F1A,RNF114,NDUFA5,CYLD,UGP2,DYNLL1,MRPL39,GGPS1,ZADH2,DUSP22,SEC11A,PDK2,ATP6V0B,MDM2,DUS4L,MINPP1,SAP30L,GM2A,PSMA8,CPOX,CYP20A1,MTMR6,KDM1B,USP36,DNAJC10,ATP1A1,CLK3,NCOA1,LTA4H,USP53,CTDP1,GNE,SUMF1,CHAC2,CSNK1A1,WRNIP1,PTPN2,GSTK1,STARD9,IRF4,NDUFV1,CWC27,DDX31,ABCD1,PTGES3,CAMK2G,PPWD1,RHOT2,NEU1,TPD52L2,FBXO41,GOLGA7,BIRC5,ACADM,SPCS3,RPS6KC1,UBE2C,SAT2,GCSH,PPCS,NDUFB6,ZDHHC8,TAP1,NHLRC3,CCNB1,ABHD14A,POLR3K,KIFC1,CYB5RL,RNASEK,MAST2,CDC25B,PLCL2,SPTSSA,DNMT1,AKT2,PBK,DDX20,AURKB,GALNT7,AMDHD2,CCNF,FOXRED1,STT3A,PTER,WDR4,PTPN7,DHTKD1,UQCRH,ZNF598,HDAC2,DDX58,PPIB,HSPH1,MUT,CHTF18,ADO,KIF23,NDUFA4,MAN2B1,METTL3,CFLAR,NDUFS4,FKBP1A,NDUFAF6,RNF121,MEX3C,DAD1,HDAC7,ATIC,BDH1,CTPS1,ATP6V0A2,PCYT2,RNF135,PIKFYVE,GNAI2,LPCAT1,TERF2,DDX28,NOA1,PIP4K2C,SEPT8,DCTD,RIT1,PKM,KDM3A,PSMB3,ADSS,EPRS,NSF,DCK,CSNK1G1,QARS,ACLY,LPCAT4,PPP3R1,VCPIP1,MAP3K5,CDK2,RNF14,NRBP1,ZC3HAV1,DNMT3A,SUZ12,RPS6KA1,RAC1,OLA1,KLHL18,ADPGK,SDHA,GNB2,FLAD1,KDM2A,UCHL5,CDKN1B,TALDO1,NAA35,MRM2,GPX4,ATP13A1,RFC3,TAOK1,CUL3,KIAA1586,GALK2,CDC23,PSMB9,POLG2,DHX57,PRDM11,HSPA4,PPP2R5A,JAK1,ACYP1,GUCY1B1,PPA2,TRIM32,B4GALT3,CSNK1D,RHEBL1,POLQ,OTUD5,TWNK,MRI1,BRAP,AGPAT3,SDF2L1,BLM,SPR,RAB11A,PIP5K1C,PTEN,CRAT,CNOT6L,MAP3K14,OSTC,UBE2M,NEK7,TRIR,PARP4,TBRG4,ANAPC2,RHOT1,MARK2,ECH1,PRDX1,POLR2A,FBXO21,GNA12,PLD3,SGSH,PRDX3,TTLL4,ATP5MC3,NAXE,ASNA1,DDX52,ADA2,MIB2,UBE2E2,NOP2,ALKBH5,MOGS,UBE2Z,TAF6L,KIF2C,SIRT2,FKBP2,USP48,MAPK14,RNF103,EDC3,UBLCP1,BCAT2,MBD4,RAP1A,EIF4A3,DPYSL2,IMPAD1,METTL14,ATG3,SRI,AKR1B1,JOSD1,NDUFB9,KIF22,TECR,OGG1,ARID4A,FGFR1OP2,TIMM50,TDP1,TRIM8,DPM1,RRM2,WDR82,STK17B,DHX15,ABHD5,UEVLD,IARS2,GALNT10,ROCK1,PSMC1,PIGN,UFC1,EPHX2,RHBDD1,UBE3C,ACAD8,N4BP2,ALDH9A1,TSTA3,OXR1,PSMA1,SEPT7,GNAS,TRMT10B,RBBP4,NANP,NAA20,PDSS2,PTDSS1,MMACHC,ASH1L,MPHOSPH8,GNPNAT1,WDYHV1,NSD3,CHKB,CHD1,FARSA,ANKLE1,PARL,RPN2,PDIA6,SCYL3,HTRA2,RLIM,ACSL5,CGAS,PSMB7,NLN,NDUFB1,PEF1,GFER,RAD54B,CANT1,USP11,SMURF1,PPP2R2D,CBX4,MIF,KIF3B,CDS2,CASP6,EYA1,TOR3A,MAN1A1,GART,PELO,TANK,GINS1,CSNK1G2,ZDHHC18,ADAM17,POLR3GL,ATP5MF,MEN1,TARS,HSPA1B,MFN2,MAPK3,ATAD2,KBTBD7,COX8A,PREPL,IDH3B,TATDN1,ATP6V1C1,TYW1B |
| 1.678e-17 | -38.63 | spindle | cellular component | GO:0005819 | 326 | 109 | 18223 | 2701 |
BCCIP,ZNF207,SKA3,CYLD,DYNLL1,POC1A,TPX2,MYH9,KIF2C,SIRT2,CCNB1,MAPK14,APP,KIFC1,CALM2,NEK6,CDC42,ABRAXAS2,KIF14,KIF22,CDC25B,CEP63,TACC3,DCTN1,PRPF19,PLK1,PSRC1,NSUN2,KIF15,TUBGCP5,CUL3,CKAP2L,CDC6,TOPORS,NUSAP1,AURKB,DIDO1,SLC25A5,SHCBP1,TMEM201,PPP2CA,KIF2A,CDC16,DSN1,KIF18B,MAP4,VPS4A,KLHL42,MAPK1,CSNK1D,ANXA11,CTDP1,KIF3B,MAPRE1,PKP4,MZT1,KLHL21,RAE1,CENPF,CDCA8,KIF23,HAUS4,RACGAP1,SPDL1,RAB11A,HAUS2,TUBGCP2,MAD2L2,NEIL2,SPAG5,FBXO5,SAC3D1,RB1,CEP104,MZT2A,SMC3,PRC1,ARHGEF2,KIFAP3,KNTC1,NUP85,MICAL3,KAT2A,TCTEX1D2,ASPM,NEK7,PARP4,JTB,MAP7D1,RANGAP1,SEPT7,KIF11,HAUS8,CBX3,KIF18A,GOLGA2,CDC27,BIRC5,FAM110A,ODF2,FAM83D,CCDC69,NUP62,PKD2,NDE1,WDR62,ESPL1,MZT2B,TERF1 |
| 1.698e-17 | -38.61 | nucleobase-containing compound biosynthetic process | biological process | GO:0034654 | 3030 | 617 | 17256 | 2622 |
ZBTB10,KDM4A,CCNL2,EDRF1,ZNF275,USF1,CIPC,SRSF4,UPRT,CRY2,ECD,ZNRD1,ZNF672,ZNF559,GABPA,MIER2,TOPORS,DIDO1,STOML2,BRMS1,SMAD2,RPS27A,ZNF689,VIPAS39,TFDP2,SMAD1,E2F2,ZNF75A,PFKP,SLC25A33,SSRP1,HIVEP3,DHX9,EZH1,CDC73,MCTS1,TFAP4,INTS7,ZNF326,FOXN2,CPSF4,SRSF11,ETV3,FOXK1,RB1CC1,ZMYND11,MYBL2,USP10,BCLAF1,SRSF5,CBFA2T2,ELK1,POLR2J,ETS2,SETD3,CNOT6,SGF29,ZNF296,KARS,SARNP,TRERF1,IVNS1ABP,PTTG1,RMI2,CREBL2,ZNF267,INO80E,SLC35B2,SAFB2,RCOR3,TCF19,ZNF420,SP100,ZKSCAN1,MTA1,DUT,GMEB1,NABP1,INTS12,ZNF226,ATF2,RPRD1B,CGGBP1,PDCL3,ADCY7,CPNE1,POLR2L,EID1,KAT7,INTS13,WBP2,POLR2D,RNPS1,E2F3,ATP6V0A1,MEF2D,DDX17,TAF2,CHCHD3,HIPK2,SNRPG,PPP5C,ZBTB11,COMMD10,GALK1,ZNF786,ZNF445,SRSF6,HABP4,JMJD6,ATP5F1B,WDR5,ETS1,NEXMIF,ZNF92,NEIL2,RPA2,ZBTB45,ERH,SUV39H2,PPP1R8,ZNF260,PRDM4,ZNF710,GTF2H2,MED22,PDPK1,TK1,GUK1,POLK,ZNF512,LDHA,DDX39A,PDE3B,RPA1,ZNF180,ZNF862,KEAP1,POLE,PITX1,LRPPRC,PML,HMGB2,PARP10,USF2,THAP5,THOC1,GPBP1L1,GNPDA1,RBM8A,CSNK2A1,SND1,BIRC2,PAPOLA,CREM,LIN9,PCNA,GLIS2,ZNF639,INTS1,ETV6,XRCC2,NOC2L,PPCDC,MYBL1,CCAR1,RYBP,SP3,BAZ2A,RAD51AP1,SNRPB,MRPL12,PBRM1,BRCA1,EAF2,USP21,CHD3,E2F4,ZNF367,DVL1,DHFR2,ZNF45,BEND6,FAM208A,NUDT11,POT1,ZNF564,FUBP1,ZCCHC9,PHB2,CENPF,CTCF,CHCHD2,CDK13,RLF,ASXL2,CNOT11,ARID1B,SUB1,RB1,MLX,MED8,MBD2,SSBP3,ZNF746,CTR9,TIMELESS,MDFIC,ICE2,MAML1,PREB,LDB1,AMD1,UTP15,RTF1,ZNF761,IRF5,ZNF174,RXRB,PALB2,PRPS2,TBPL1,PRMT7,RUVBL2,ATP5F1A,TRAF7,UGP2,SUCLG1,ARID2,FOXM1,DYNLL1,XAB2,ZNF416,RRAGC,COMMD8,ZNF121,NRF1,ZBTB21,ZNF473,KMT5C,ZNF302,RPAP1,TARDBP,SAP30L,ZNF583,DVL2,KDM3B,POLR2G,ZNF780B,BTG2,NFATC2,KDM1B,SRSF1,ZNF700,RBL1,MAFK,ZNF436,DNAJC17,XRCC3,NCOA1,SMAD4,RAD51D,INTS2,SLC30A9,CTDP1,NADSYN1,NIFK,CDC40,MTERF1,AGO2,ARID5A,GTF3A,NKRF,PAGR1,RMI1,WRNIP1,IRF4,SS18L1,PTGES3,POLR1B,RNLS,RBM15B,RPRD1A,HMGN5,ZNF202,ZMYM5,TOP3A,PCGF1,BIRC5,L3MBTL3,TFE3,CDCA7L,BBX,E2F1,IMPDH1,RBPJ,TAF12,NR2F2,PGAM1,HIPK3,IFI16,PPCS,MAX,ZNF496,TXN,CXXC1,NANS,CCNB1,COMMD6,POLR3K,MYEF2,PA2G4,NOL11,FIZ1,ZNF200,TAF5L,SLC26A2,ZNF800,DNMT1,CDC5L,ZNF524,KLF10,ELOA,AMDHD2,USP22,RFC2,CBFB,PRIM1,IWS1,HHEX,BRD2,DHTKD1,BTF3,ARRB2,CCDC59,HDAC2,PTOV1,COX5B,EWSR1,POLR2K,PRKAA1,RRM1,NOTCH2,PMF1,SUPT7L,ZNF518A,ZNF79,VPS25,NPLOC4,CNOT3,YY1AP1,LHX8,KLF16,ATIC,HDAC7,CTPS1,ATP6V0A2,CYC1,EEF1D,TERF2,PHF10,ZNF84,PRIM2,ELL2,ZNF574,DCTD,ARID1A,PKM,KDM3A,TWISTNB,PHF6,XRCC5,ADSS,ZNF777,SERTAD2,ZFP92,DCK,RBMX,MED15,CEBPG,PIAS2,GPI,YY1,RNF14,NRBP1,NUDT3,ZNF511,ATXN3,ZBTB37,SUZ12,ADPGK,TERF2IP,SPINDOC,FLAD1,ZNF75D,KDM2A,UCHL5,LPIN2,ADCY9,CDK12,SAP30,BRD4,RFC3,ERF,DRAP1,SLBP,ELP4,EDF1,POLG2,GAR1,TRIM28,CENPU,SUPT16H,PRDM11,VEZF1,RAD51C,ZNF282,HINT1,SAFB,GUCY1B1,STAT1,ATF6,BEND3,EYA2,ATMIN,POLQ,POU3F2,NCOR2,DEPDC1,TWNK,MECP2,TCF3,MYNN,ARGLU1,BLM,FOXO3,HMG20A,MAD2L2,GTF2F1,WWP2,CCNK,ELP5,CARF,CREB1,CNOT6L,CITED2,NCOA2,TSHZ1,ZFP64,KAT2A,ILF3,RFXANK,ADSL,COMMD4,KLF6,POLR2A,CBX3,ZHX1,ATP5MC3,TFDP1,KHSRP,NAXE,DDX5,TAF6,PURA,RORB,CCNC,POLA2,ADA2,ZNF76,IER2,KMT2E,PHRF1,ZNF107,SIRT2,TAF6L,SNRPD3,COMMD5,MAPK14,ATP5PF,SNAPC4,ZNF696,MBD4,EIF4A3,JAZF1,PHTF1,ZBTB22,TCEA1,OGG1,ARID4A,CARM1,ELOF1,DEAF1,RIOX2,RRM2,SOX4,KMT2C,PRPSAP1,ASF1B,UBTF,PAF1,BRWD1,PQBP1,CRCP,BAZ1B,ZNF268,CHEK2,ZNF768,NACA,MED13L,MEF2A,THRAP3,SRRT,TTF1,DTL,LYAR,NFATC3,ZNF449,MED10,BUD31,ZNF335,YBX1,ACAD8,ZNF189,VOPP1,POLR2I,TSTA3,NUDT4,CIC,SLTM,ISG15,DAPK3,UAP1,NFIL3,NUP62,ZFP90,DNPH1,RBBP4,HNRNPDL,NIPSNAP2,ADNP2,ZBTB24,MBD1,TCF12,ASH1L,GNPNAT1,MPHOSPH8,UCK2,UCK1,PLAGL2,SMARCA4,NSD3,IRF3,CHD1,MXD1,MEAF6,SAP130,RRN3,CD3EAP,AKAP8,CHTOP,UTP4,ZNF770,RLIM,CSTF1,POU2AF1,CGAS,ZNF500,PCGF6,ATXN1,OGDH,MBD3,ZNF317,STAT6,ARNTL,AKNA,MAPK1,BRD9,CBX4,NAT14,DNAJC2,ZNF316,EYA1,SCYL1,KLF13,PAWR,MXD4,HDDC2,GART,KMT5A,NABP2,ANP32A,BRD7,STAT3,SAMD4B,TGFB1,AMPD2,GTF3C6,PSPC1,HELB,MIER1,NADK2,POLR3GL,RCOR1,MEN1,ATP5MF,ZNF407,SYMPK,TFEB,MAPK3,CNOT9,ATAD2,KMT2B,ACAT1,SRSF3,ZMIZ1,TERF1 |
| 1.874e-17 | -38.52 | ENK_UV_RESPONSE_KERATINOCYTE_DN | MSigDB lists | ENK_UV_RESPONSE_KERATINOCYTE_DN | 472 | 143 | 17377 | 2626 |
RAB14,RBM8A,CUL1,BIRC2,MBD4,BCAT2,DLG5,SRI,TRA2B,RP2,DNMT1,ABCC5,SNRNP200,CELSR2,GMFB,PSMG1,MCL1,TOPORS,UTP3,SLC25A5,ZFAND5,DHX15,HSPB11,STT3A,LUC7L3,MAP4,OGT,PRPF4,B4GALT2,DDX42,PTOV1,UBE2D3,DHX9,RRM1,CTCF,TOP2B,RGS2,ITGB5,TFAP4,SLC31A1,RB1,MBD2,XPA,KIFAP3,AFF1,CPSF4,FDFT1,SRSF11,ZMYND11,DCAF8,ACSL3,SUGP2,KRAS,ADRB2,EIF4H,GOSR1,ZDHHC3,NMT2,EPRS,GOLGA4,RBMX,SLC16A1,MDH1,MAP3K5,CDK2,MRPL3,USP7,TOMM20,SLC2A1,ACTR3,TPX2,STARD7,CPNE3,KTN1,ATP2A2,SP100,SIAH1,MTMR4,DUT,GRSF1,ADCY9,CDKN1B,EBAG9,ADCY7,BIRC3,EID1,CDC123,CPOX,SLBP,DNAJA1,CDC23,H2AFV,DDX17,SRSF1,KIF2A,ACYP1,HNRNPR,GOLGA8A,HPS5,FKBP5,SNRPG,SMAD4,ZNF146,PRPF4B,NDUFS1,TRIP12,MECP2,GNE,PAWR,UBE4A,CSNK1A1,FOXO3,TUBGCP2,FZD6,ERH,PPIG,RRBP1,ANP32A,CREB1,SLC35A1,MYO5A,TMX1,YTHDC1,STAU1,ELOVL5,TACC1,PRKDC,ATP2C1,RABIF,MACF1,PICALM,ZFR,CBX3,MTMR3,PFDN4,CCDC6,KHSRP,PKD2,ACADM,UBE2C,PURA,TERF1,GCSH |
| 1.875e-17 | -38.52 | DACOSTA_UV_RESPONSE_VIA_ERCC3_DN | MSigDB lists | DACOSTA_UV_RESPONSE_VIA_ERCC3_DN | 819 | 215 | 17377 | 2626 |
CCDC93,UBL3,PNISR,ADAM10,YTHDF3,CUL1,CSNK2A1,AGFG1,MAPK14,ZNF804A,DST,RAP1A,ASAP2,RABGAP1L,RAD23B,ATP13A3,PDS5B,NUP153,MAST2,MYBL1,TIPARP,ARID4A,PTPRK,SRPK2,USP34,VPS13B,RYBP,SP3,RHOBTB3,KLF10,SEPT9,NCK1,TLK1,SLC16A7,WDHD1,BRCA1,CBFB,DHX15,EIF3A,KRIT1,MAP3K4,TRAM2,U2SURP,OGT,BAZ1B,ROCK1,FAM208A,NUMB,DDX42,FUBP1,UBE2D3,PPP1R12A,TRIO,CENPF,TIA1,MED13L,KLC1,KIF23,CTCF,MEF2A,CDK13,PPP3CB,RAB6A,NCKAP1,RLF,PARN,RB1,NFATC3,SMC3,MBD2,PHF14,DAPK1,TPST1,MSH2,AHDC1,KIFAP3,MDFIC,AFF1,FBXL7,PIKFYVE,FAM171A1,ABCC1,SOCS5,CYTH1,IFRD1,PRIM2,RB1CC1,ELL2,ZMYND11,ACSL3,FXR1,KDM3A,MTR,NMT2,CAND1,GOLGA4,CDC27,SETD3,PPP3R1,YY1,PDLIM5,N4BP2L2,USP7,TCF12,UBR2,SUZ12,UCK2,LYN,STAM,APP,CHD1,PAIP1,ANKRD28,RAB21,AHCTF1,SP100,TNFAIP8,NVL,UTP18,KIF14,ADCY9,SOCS6,CDKN1B,TP53BP2,AQR,ATF2,ABI1,ANKLE2,KDM3B,SHOC2,MKLN1,FAM172A,E2F3,ATXN1,GALK2,ERC1,DDX17,PPP2CA,KIF2A,VEZF1,RAD51C,CDC16,PPP2R5A,CERS6,TAB2,WDR7,RBMS1,NCOA1,XRCC4,ZBTB11,TSPAN5,SMAD4,PARD3,USP13,DNAJC2,NCOR2,PKP4,CDS2,TRIP12,MECP2,GNE,DBF4,TRAK1,SLC25A12,PAWR,MYO9B,DCUN1D4,BLM,CSNK1A1,FOXO3,PIP4K2A,PTPN2,HOMER1,KLHL20,PTEN,FUT8,TANK,LTN1,UPF2,MAP3K14,CREB1,MTX2,NCOA2,MICAL3,MSH6,GINS1,MOB4,ADAM17,SNX2,NEK7,BTAF1,ATP2C1,RCOR1,KLF6,MACF1,KIF11,PICALM,MTMR3,UTP20,NEK1,CCDC6,OSBPL8,PARG,HNRNPH3,BBX,MAPK6,LRPPRC,PKD2,RBPJ,RGL1,SRSF3,ZMIZ1,NR2F2,TERF1,TMEM131 |
| 2.603e-17 | -38.19 | MORF_PPP1CC | MSigDB lists | MORF_PPP1CC | 158 | 68 | 17377 | 2626 |
IMMT,H2AFZ,PTTG1,STMN1,PABPC4,RAD23A,KIFC1,IARS,GOT2,DUT,MRPS27,CS,TRA2B,TCEA1,PDIA6,DNMT1,SRP72,DEAF1,SNRNP200,PPT1,PPIE,VDAC2,DNAJC9,SLBP,VDAC1,MCM2,CBFB,CHAF1A,SRSF1,CDC16,HNRNPR,SAFB,PPM1G,BAZ1B,HDAC2,SSRP1,RMND5A,MAPRE1,RRM1,XPO7,HDDC2,SMC3,NDUFV1,TNPO3,ANP32A,PTGES3,NUDC,IFRD1,ELOVL5,MLEC,NASP,PRKDC,TUFM,DCTD,CCT8,SNRPA,TARS,XRCC5,SDHB,EPRS,TFDP1,PRPS2,LRPPRC,KHSRP,RUVBL2,RBBP4,ESPL1,PTDSS1 |
| 2.641e-17 | -38.17 | SOTIRIOU_BREAST_CANCER_GRADE_1_VS_3_UP | MSigDB lists | SOTIRIOU_BREAST_CANCER_GRADE_1_VS_3_UP | 140 | 63 | 17377 | 2626 |
TXN,H2AFZ,MCM10,HJURP,FOXM1,POLR2K,PTTG1,CENPF,LAGE3,TPX2,CDCA3,CDCA8,RACGAP1,JMJD6,KIF2C,BLM,CCNB1,NCAPG,STMN1,SPAG5,FBXO5,KIFC1,OIP5,CCNA2,KIF14,PRC1,TIMELESS,GTSE1,RNASEH2A,TACC3,GINS1,PLK1,ASPM,MRPL12,KIF15,GTPBP4,MYBL2,MKI67,DNAJC9,RRM2,NUSAP1,AURKB,PKMYT1,NUTF2,MCM2,DDX39A,KIF11,H2AFV,RAD54B,DSN1,ORMDL2,KIF18B,BIRC5,CEP55,E2F1,KPNA2,SNRPG,CDK2,CCNB2,UBE2C,ESPL1,BYSL,POLQ |
| 2.668e-17 | -38.16 | GSE15750_DAY6_VS_DAY10_TRAF6KO_EFF_CD8_TCELL_UP | MSigDB lists | GSE15750_DAY6_VS_DAY10_TRAF6KO_EFF_CD8_TCELL_UP | 188 | 76 | 17377 | 2626 |
SKA3,FOXM1,TPX2,NUF2,ORC1,STMN1,TCF19,SYNRG,MIS12,APLP2,PCNA,CCNA2,DUT,SEPT11,KIF22,CCAR1,TACC3,PLK1,CCT2,MND1,PSRC1,CCDC138,RAD51AP1,PBK,CPOX,MKI67,EZR,CKAP2L,RRM2,CDC6,CDCA2,AURKB,SMC2,ANLN,CCNF,SHCBP1,PRIM1,KIF2A,KIF18B,CEP55,FKBP5,GEN1,MAPK1,MCM10,DEPDC1,CLSPN,CENPF,RRM1,CDCA3,KIF23,PXMP2,RACGAP1,NCAPG,SPAG5,NUP205,DTL,GTSE1,NDUFS8,CLDND1,CENPM,TK1,CSRP1,ASPM,MYBL2,PLAA,POLE,BIRC5,PFDN4,SNAP29,RBMX,CDCA7L,TFDP1,CDCA5,HMGB2,UBE2C,CCNB2 |
| 2.774e-17 | -38.12 | aromatic compound biosynthetic process | biological process | GO:0019438 | 3101 | 628 | 17256 | 2622 |
ZBTB10,KDM4A,CCNL2,EDRF1,ZNF275,USF1,CIPC,SRSF4,UPRT,CRY2,ECD,ZNRD1,ZNF672,ZNF559,GABPA,MIER2,TOPORS,DIDO1,STOML2,BRMS1,SMAD2,RPS27A,ZNF689,VIPAS39,TFDP2,SMAD1,E2F2,ZNF75A,PFKP,SLC25A33,SSRP1,HIVEP3,DHX9,EZH1,CDC73,MCTS1,TFAP4,INTS7,ZNF326,FOXN2,CPSF4,SRSF11,ETV3,FOXK1,RB1CC1,ZMYND11,MYBL2,USP10,BCLAF1,SRSF5,CBFA2T2,ELK1,POLR2J,ETS2,SETD3,CNOT6,SGF29,ZNF296,KARS,SARNP,TRERF1,IVNS1ABP,PTTG1,RMI2,CREBL2,ZNF267,INO80E,SLC35B2,SAFB2,RCOR3,TCF19,ZNF420,SP100,ZKSCAN1,MTA1,DUT,GMEB1,NABP1,INTS12,ZNF226,ATF2,RPRD1B,CGGBP1,PDCL3,ADCY7,CPNE1,POLR2L,EID1,KAT7,INTS13,WBP2,POLR2D,RNPS1,E2F3,ATP6V0A1,MEF2D,DDX17,TAF2,CHCHD3,HIPK2,PDXK,SNRPG,PPP5C,ZBTB11,COMMD10,GALK1,ZNF786,ZNF445,SRSF6,HABP4,JMJD6,ATP5F1B,WDR5,ETS1,NEXMIF,ZNF92,NEIL2,RPA2,ZBTB45,ERH,SUV39H2,PPP1R8,ZNF260,PRDM4,ZNF710,GTF2H2,MED22,PDPK1,TK1,GUK1,POLK,ZNF512,LDHA,DDX39A,PDE3B,RPA1,ZNF862,ZNF180,KEAP1,POLE,PITX1,LRPPRC,PML,HMGB2,PARP10,USF2,THAP5,COX15,THOC1,GPBP1L1,GNPDA1,RBM8A,CSNK2A1,SND1,BIRC2,PAPOLA,CREM,LIN9,PCNA,GLIS2,ZNF639,INTS1,ETV6,XRCC2,NOC2L,PPCDC,MYBL1,CCAR1,RYBP,SP3,BAZ2A,RAD51AP1,SNRPB,MRPL12,PBRM1,BRCA1,EAF2,USP21,CHD3,E2F4,ZNF367,DVL1,DHFR2,ZNF45,BEND6,FAM208A,NUDT11,POT1,ZNF564,FUBP1,ZCCHC9,PHB2,CENPF,CTCF,CHCHD2,CDK13,RLF,ASXL2,CNOT11,RSAD1,ARID1B,SUB1,RB1,MLX,MED8,MBD2,SSBP3,ZNF746,CTR9,TIMELESS,MDFIC,ICE2,MAML1,PREB,LDB1,AMD1,UTP15,RTF1,ZNF761,IRF5,ZNF174,RXRB,PALB2,PRPS2,TBPL1,PRMT7,RUVBL2,ATP5F1A,TRAF7,UGP2,SUCLG1,ARID2,FOXM1,DYNLL1,XAB2,ZNF416,RRAGC,COMMD8,ZNF121,NRF1,ZBTB21,ZNF473,KMT5C,ZNF302,RPAP1,TARDBP,SAP30L,ZNF583,DVL2,KDM3B,POLR2G,ZNF780B,BTG2,CPOX,NFATC2,KDM1B,SRSF1,ZNF700,RBL1,MAFK,ZNF436,DNAJC17,XRCC3,NCOA1,SLC25A39,SMAD4,RAD51D,INTS2,SLC30A9,CTDP1,NADSYN1,NIFK,CDC40,MTERF1,AGO2,ARID5A,GTF3A,NKRF,PAGR1,RMI1,WRNIP1,IRF4,SS18L1,PTGES3,POLR1B,RNLS,RBM15B,RPRD1A,HMGN5,ZNF202,ZMYM5,TOP3A,PCGF1,BIRC5,L3MBTL3,TFE3,CDCA7L,BBX,E2F1,IMPDH1,RBPJ,TAF12,NR2F2,PGAM1,HIPK3,IFI16,PPCS,MAX,ZNF496,TXN,CXXC1,NANS,CCNB1,COMMD6,POLR3K,MYEF2,PA2G4,NOL11,FIZ1,ZNF200,TAF5L,SLC26A2,ZNF800,DNMT1,CDC5L,ZNF524,KLF10,ELOA,AMDHD2,USP22,CBFB,RFC2,PRIM1,IWS1,HHEX,BRD2,DHTKD1,BTF3,ARRB2,CCDC59,HDAC2,PTOV1,COX5B,EWSR1,POLR2K,PRKAA1,RRM1,NOTCH2,PMF1,SUPT7L,ZNF518A,ZNF79,VPS25,NPLOC4,CNOT3,YY1AP1,LHX8,KLF16,ATIC,HDAC7,CTPS1,ATP6V0A2,CYC1,EEF1D,TERF2,PHF10,ZNF84,PRIM2,ELL2,ZNF574,DCTD,ARID1A,PKM,KDM3A,TWISTNB,PHF6,XRCC5,ADSS,ZNF777,SERTAD2,ZFP92,DCK,RBMX,MED15,CEBPG,PIAS2,GPI,YY1,RNF14,NRBP1,NUDT3,ZNF511,ATXN3,ZBTB37,SUZ12,UROD,ADPGK,TERF2IP,SPINDOC,FLAD1,ZNF75D,KDM2A,UCHL5,LPIN2,ADCY9,CDK12,SAP30,BRD4,RFC3,ERF,DRAP1,SLBP,ELP4,EDF1,POLG2,GAR1,TRIM28,CENPU,SUPT16H,PRDM11,VEZF1,RAD51C,ZNF282,HINT1,SAFB,GUCY1B1,STAT1,ATF6,BEND3,EYA2,ATMIN,POLQ,POU3F2,NCOR2,DEPDC1,TWNK,MECP2,TCF3,MYNN,ARGLU1,BLM,SPR,FOXO3,HMG20A,MAD2L2,GTF2F1,WWP2,CCNK,ELP5,CARF,CREB1,CNOT6L,CITED2,NCOA2,TSHZ1,ZFP64,KAT2A,ILF3,RFXANK,ADSL,KLF6,COMMD4,POLR2A,CBX3,ZHX1,ATP5MC3,TFDP1,KHSRP,NAXE,DDX5,TAF6,PURA,RORB,CCNC,POLA2,ADA2,ZNF76,IER2,KMT2E,PHRF1,ZNF107,SIRT2,TAF6L,SNRPD3,COMMD5,MAPK14,ATP5PF,SNAPC4,ZNF696,MBD4,EIF4A3,JAZF1,PHTF1,ZBTB22,TCEA1,OGG1,ARID4A,CARM1,ELOF1,DEAF1,RIOX2,RRM2,SOX4,KMT2C,PRPSAP1,ASF1B,UBTF,PAF1,BRWD1,PQBP1,CRCP,BAZ1B,ZNF268,CHEK2,ZNF768,NACA,MED13L,MEF2A,THRAP3,SRRT,TTF1,DTL,LYAR,NFATC3,ZNF449,MED10,ZNF335,BUD31,YBX1,ACAD8,ZNF189,VOPP1,ATP5IF1,POLR2I,TSTA3,NUDT4,CIC,SLTM,ISG15,DAPK3,UAP1,NFIL3,NUP62,ZFP90,DNPH1,RBBP4,HNRNPDL,NIPSNAP2,ADNP2,ZBTB24,MBD1,TCF12,MMACHC,ASH1L,GNPNAT1,MPHOSPH8,UCK2,SMARCA4,UCK1,PLAGL2,NSD3,IRF3,CHD1,MXD1,MEAF6,SAP130,RRN3,CD3EAP,AKAP8,CHTOP,UTP4,TMEM14C,ZNF770,RLIM,CSTF1,POU2AF1,CGAS,ZNF500,PCGF6,ATXN1,OGDH,MBD3,ZNF317,STAT6,ARNTL,AKNA,BRD9,MAPK1,CBX4,NAT14,DNAJC2,ZNF316,EYA1,SCYL1,KLF13,PAWR,MXD4,HDDC2,GART,KMT5A,NABP2,ANP32A,BRD7,STAT3,MYO5A,AMPD2,SAMD4B,TGFB1,GTF3C6,PSPC1,HELB,MIER1,NADK2,POLR3GL,RCOR1,MEN1,ATP5MF,ZNF407,SYMPK,TFEB,MAPK3,CNOT9,ATAD2,KMT2B,ACAT1,SRSF3,ZMIZ1,TERF1 |
| 3.044e-17 | -38.03 | GO_MACROMOLECULE_CATABOLIC_PROCESS | MSigDB lists | GO_MACROMOLECULE_CATABOLIC_PROCESS | 893 | 229 | 17377 | 2626 |
PDCD6IP,AGRN,RBM8A,HEXB,CUL1,UBE2Z,SIRT2,GYG1,USP48,UBQLN2,CCNB1,UBE2I,BECN1,BIRC2,PABPC4,RNF103,FBXO22,EDC3,RPL23A,PCYOX1L,CALM2,CDK5,PSMD1,EIF4A3,RAD23B,PCBP2,USP34,PLK1,EXOSC6,RBX1,TOPORS,AURKB,USP22,CCNF,USP21,RPL37,RPS27A,PSMD8,RPS14,AXIN1,NAGLU,ATE1,CHEK2,SMG9,VPS4A,FBXL3,CLN3,ARRB2,NGLY1,PSMC1,RPS26,LONP2,CAPN1,UBE2D3,RPS15,TMUB1,DNAJB2,UBXN1,GSPT2,SDC2,KCTD17,RPL15,ZNRF3,THRAP3,PSMD9,PARN,VPS25,RHBDD1,PRPF18,NPLOC4,CNOT3,GNS,DTL,RNF121,EXOSC7,FBXO7,FBXL7,UBE3C,ZRANB1,LRSAM1,PHKG2,PABPC1,ERLIN1,MAN1B1,RPS10,RPL6,PSMA1,USP10,RPS24,EXOSC9,UBE4B,SYVN1,PATL1,PSMB3,ISG15,PSMC4,RPL36,DERL1,KPNA1,CDC27,KLHL15,SIAH2,USP32,CTSA,CNOT6,RNF14,HEXA,RNF139,USP7,ATXN3,CYLD,RPLP2,UBR2,PTTG1,ANKIB1,PAIP1,RPL11,USP5,RAD23A,CSDE1,UBXN2A,MDM2,PSMA6,SIAH1,UCHL5,KIF14,MTA1,EXOSC1,SOCS6,NSFL1C,TTC3,ANAPC7,RNASEH2A,RNF19A,CLN6,HTRA2,PRPF19,RLIM,SNX25,RPL29,RPL35,SEC61B,POLR2G,PSMA8,PPT1,RAB7A,POLR2D,RNPS1,CUL3,PSMB7,RPL38,CDC23,EDEM2,PSMB9,RPS9,RPSA,USP36,ANKZF1,PPP2CA,DNAJC10,IDE,CDC16,LSM6,UBXN2B,PSMD3,ARNTL,RPLP1,UHRF2,SEL1L,RNF38,CHMP4B,TRIM32,FAU,USP11,SMURF1,CHID1,USP13,RPS2,TRIP12,KLHL21,SDF2L1,UBE4A,CSNK1A1,DNAJB9,WWP2,HERC3,CAPN2,PSMD2,CTSS,KLHL20,HUWE1,RPL17,PPP1R8,PELO,DCP1A,GTSE1,RPL19,UPF2,UBE3B,CNOT6L,FBXL19,LYPLA2,RNF5,TGFB1,TNFAIP3,RNASEH2C,USP42,RPL8,FBXO9,RFFL,ANAPC2,RPL27A,SH3GLB1,FBXO21,SGSH,KEAP1,UPF1,RPL32,TATDN2,CTBS,PML,USP20,KHSRP,HMGB2,TATDN1,UBE2C,ANAPC4,DDB1,FAF1 |
| 3.076e-17 | -38.02 | LASTOWSKA_NEUROBLASTOMA_COPY_NUMBER_DN | MSigDB lists | LASTOWSKA_NEUROBLASTOMA_COPY_NUMBER_DN | 713 | 193 | 17377 | 2626 |
MIB2,COX15,PDCD6IP,PPCS,LUZP1,KDM4A,GPBP1L1,GLUD1,EBNA1BP2,TAF6L,CCNL2,USP48,OAT,EIF1B,CUTC,CMTM6,BIRC2,PARK7,ATPAF1,DLG5,NUP210,CDC42,SRSF4,TXLNA,ZFYVE27,MAST2,ECD,RNF26,OGG1,KCNAB2,TACC3,TRIM8,TMEM115,LAP3,VHL,MRPL43,MKI67,KIF15,DCUN1D5,PBRM1,ICMT,FOXRED1,DHX15,CLNS1A,EPB41,NECAP2,C1orf122,MKNK1,HSPB11,RAD18,WDR11,STT3A,ATE1,NGLY1,PDCD4,HIVEP3,TBC1D12,RPL15,TOP2B,PPP3CB,THRAP3,RAB6A,RLF,ZNF518A,PITHD1,WDR48,LYAR,CEP104,MED8,INPP5A,RIMS3,PIGG,EI24,AHDC1,MRPL48,ACAD8,ZRANB1,NSUN4,HP1BP3,SRSF11,TIMM8B,MAP7D1,UBE4B,ARID1A,NCDN,PI4K2A,PTPRF,SDHB,GOLGA4,QARS,RBBP4,C11orf1,GLT8D1,MMACHC,RAF1,RPS6KA1,UROD,WDTC1,VTI1A,RRAGC,TM9SF3,STMN1,MEAF6,ANKRD28,PHC2,ATP6V0B,APLP2,TBC1D14,PPME1,CLCN6,ANKRD13C,FAM76B,MINPP1,TMEM136,RNF169,SHOC2,HPDL,PPT1,PPIE,PCGF6,DNAJC9,FRAT2,SLBP,CADM1,AZI2,BUD13,PEF1,TMEM201,JAK1,DDOST,SCAP,HNRNPR,VPS26B,CHCHD1,ZNF436,H2AFX,PPP2R2D,SLC30A9,ZNF445,TRAK1,FAM76A,TKT,UBE4A,NCAPG,TUBGCP2,MFSD10,MAD2L2,RPA2,ADD3,DNAJC8,CLIC4,PTEN,PPP1R8,SEC24C,BTF3L4,ERI3,IFT46,LYPLA2,CAMK2G,NUDC,RBM15B,B3GALT6,ZDHHC18,RHOA,NASP,TMEM126B,BTAF1,ZNF202,MIER1,ARHGEF12,MACF1,KIF11,PICALM,BSDC1,SH3GLB1,SMAP2,MFN2,SEC23IP,RPL32,PRDX3,TATDN2,HNRNPH3,CAPN7,ACAT1,ZRANB2,MRFAP1L1,TAF12,RBPJ,ZMIZ1,PGAM1,CPEB2,FAF1,S100PBP |
| 3.596e-17 | -37.86 | macromolecule catabolic process | biological process | GO:0009057 | 1007 | 252 | 17256 | 2622 |
PDCD6IP,AGRN,HEXB,RBM8A,CUL1,UBE2Z,NHLRC3,SIRT2,GYG1,SND1,UBQLN2,CCNB1,UBE2I,USP48,BECN1,BIRC2,RNF103,FBXO22,PABPC4,EDC3,RPL23A,PCYOX1L,CDK5,PSMD1,EIF4A3,METTL14,RAD23B,AP2B1,PCBP2,USP34,PLK1,EXOSC6,RBX1,TOPORS,USP22,AURKB,CCNF,USP21,RPL37,RPS27A,PSMD8,RPS14,AXIN1,NAGLU,ATE1,ARRDC1,CHEK2,CLU,VPS4A,KLHL42,SMG9,FBXL3,CLN3,ARRB2,NGLY1,RPS26,PSMC1,LONP2,CAPN1,UBE2D3,RMND5A,RPS15,TMUB1,UBXN1,GSPT2,TATDN3,KCTD17,SDC2,RPL15,THRAP3,ZNRF3,PSMD9,CNOT11,PARN,METTL3,VPS25,RHBDD1,PRPF18,CNOT3,NPLOC4,GNS,DTL,RNF121,EXOSC7,ZNRF2,FBXO7,FBXL7,ZRANB1,LRSAM1,PABPC1,PHKG2,RB1CC1,ERLIN1,MAN1B1,RPL6,RPS10,USP10,RPS24,PSMA1,EXOSC9,UBE4B,SYVN1,ARMC8,PATL1,PSMB3,ISG15,PSMC4,RPL36,DERL1,KPNA1,CDC27,KLHL15,SIAH2,DCAF11,USP32,CNOT6,CTSA,ECPAS,HEXA,RNF139,USP7,ATXN3,CYLD,RPLP2,UBR2,PTTG1,PAIP1,RPL11,RAD23A,USP5,CSDE1,UBXN2A,PSMA6,MDM2,SIAH1,MTA1,KIF14,UCHL5,EXOSC1,SOCS6,NSFL1C,ANAPC7,TTC3,RNASEH2A,CLN6,SPSB3,HTRA2,RLIM,PRPF19,CHP1,SNX25,RPL29,SEC61B,RPL35,POLR2G,PPT1,PSMA8,RAB7A,CUL3,RNPS1,POLR2D,PSMB7,RPL38,EDEM2,CDC23,PSMB9,TOLLIP,RPS9,RPSA,USP36,BTBD1,PPP2CA,ANKZF1,DNAJC10,CDC16,IDE,LSM6,UBXN2B,PSMD3,NT5C3B,ARNTL,RNF38,SEL1L,RPLP1,CHMP4B,TRIM32,USP11,SMURF1,AP2S1,CHID1,USP13,RPS2,TRIP12,MANBA,SDF2L1,UBE4A,CSNK1A1,DNAJB9,TUT4,WWP2,CAPN2,PSMD2,CTSS,KLHL20,RPL17,PPP1R8,PELO,DCP1A,GTSE1,LTN1,RPL19,UPF2,CNOT6L,FBXL19,RNF5,LYPLA2,TGFB1,SAMD4B,TNFAIP3,RNASEH2C,TRIR,USP42,RPL8,RFFL,FBXO9,ANAPC2,WDR81,RPL27A,SH3GLB1,HSPA1B,CNOT9,CTSL,FBXO21,SGSH,KEAP1,UPF1,RPL32,PLAA,TATDN2,CTBS,PML,KHSRP,USP20,PPP1R11,HMGB2,DDX5,TATDN1,WDR91,UBE2C,ANAPC4,DDB1,FAF1 |
| 3.885e-17 | -37.79 | GO_SPLICEOSOMAL_COMPLEX | MSigDB lists | GO_SPLICEOSOMAL_COMPLEX | 159 | 68 | 17377 | 2626 |
SART1,IVNS1ABP,XAB2,SF3B1,RBM8A,DHX8,USP39,SNRPD3,SF3B2,HNRNPA2B1,EIF4A3,GPATCH1,AQR,PRPF19,CDC5L,SNRNP200,SNRPB,PPIE,HNRNPF,CRNKL1,SREK1,PRPF3,TXNL4A,LUC7L,DHX15,RHEB,SRSF1,SUGP1,HNRNPR,DHX16,LSM6,LUC7L3,PRPF4,SNRPG,SMNDC1,PRPF4B,PRPF38B,CDC40,ZCCHC8,PDCD7,PRPF39,PRPF18,RBM17,SNRNP25,CTNNBL1,CWC27,PPP1R8,EFTUD2,BUD31,ZNF326,YBX1,PABPC1,HNRNPM,LUC7L2,HELB,PPWD1,API5,DDX39A,SF3A2,SNRPA,DDX23,UPF1,RBM25,SYNCRIP,HNRNPH3,RBMX,DDX5,SNRNP70 |
| 3.948e-17 | -37.77 | DNA repair | biological process | GO:0006281 | 501 | 149 | 17256 | 2622 |
ALKBH5,UBE2I,PARK7,FANCI,MBD4,FANCL,PCNA,CYREN,PARPBP,XRCC2,RAD23B,PDS5B,KIF22,CRY2,TCEA1,OGG1,CDC5L,COPS8,TDP1,ERCC1,RBX1,RAD51AP1,MRNIP,WDHD1,UBE2V1,BRCA1,RFC2,GINS4,CHAF1A,DOT1L,RAD18,RPS27A,TONSL,CHEK2,COPS6,SLF1,SSRP1,UBE2D3,RECQL,NSMCE4A,CLSPN,POLR2K,MUM1,CIB1,WDR48,NPLOC4,JMY,DTL,SMC3,XPA,MSH2,TIMELESS,POLR2I,USP10,MPG,ISG15,XRCC5,PAXX,PALB2,POLR2J,CDCA5,RUVBL2,YY1,ZNF830,CDK2,USP7,BCCIP,ATXN3,FOXM1,XAB2,SUMO2,PTTG1,CHD1L,PMS2,RMI2,INO80E,RPAIN,RAD23A,ANKLE1,BABAM2,KDM2A,UCHL5,MTA1,NABP1,AQR,RNASEH2A,SPIDR,PRPF19,MND1,RFC3,POLR2L,POLR2G,BTG2,PPIE,TAOK1,POLR2D,DCLRE1C,FANCE,POLG2,TRIM28,RAD54B,SUPT16H,RAD51C,FAAP100,NSMCE2,H2AFX,XRCC3,PPP5C,GEN1,XRCC4,EYA2,RAD51D,POLQ,SLC30A9,TRIP12,SHPRH,EYA1,BABAM1,SMC6,BLM,PAGR1,RMI1,MAD2L2,NEIL2,NEXMIF,WRNIP1,RFWD3,RPA2,RBM17,HUWE1,NABP2,COPS7B,GTF2H2,MSH6,HMGN1,POLK,HELB,PRKDC,PARP4,TOP3A,MEN1,POLR2A,RPA1,UPF1,POLE,NEIL3,HMGB2,SLF2,DDB1 |
| 4.225e-17 | -37.70 | GRAESSMANN_RESPONSE_TO_MC_AND_DOXORUBICIN_DN | MSigDB lists | GRAESSMANN_RESPONSE_TO_MC_AND_DOXORUBICIN_DN | 715 | 193 | 17377 | 2626 |
ZBED3,ST13,WDR13,AP3M2,ENSA,CSNK2A1,MRPL19,SSR1,PAPOLA,IL6ST,RAB4A,RAD23B,FBXW2,ZBTB22,RP2,SMARCE1,ZNRD1,SENP1,SEH1L,MRPL32,DRAM2,SRSF10,USP34,METTL1,SP3,TDP1,NRAS,AATF,PBK,GMFB,MRPL12,TMEM216,SREK1,PSMG1,WDR82,CDC6,USP22,NUTF2,MCM2,MAP3K4,ALG3,TBC1D17,WDR4,PQBP1,OGT,ATE1,ACTB,POT1,NUMB,FUBP1,UBE2D3,HIVEP3,NSMCE4A,KRBA1,ZCCHC8,DHPS,ZNF768,DHX9,NKD2,RRM1,TIA1,NOTCH2,PMF1,PRPF39,CDC73,RHBDD1,DTL,TFAP4,C12orf10,VASP,EIF2S2,EXOSC7,KLHL5,INTS7,HDAC7,MBD2,TIMELESS,FOXN2,ALDH18A1,LPCAT1,LUC7L2,ABCC1,POLR2I,ERLIN1,DCAF8,BCLAF1,GORASP2,TOMM40,ELK1,METTL22,ZDHHC3,PTPRF,CAT,MTHFD2,HSPBP1,SYNCRIP,TMEM168,PIAS2,CEBPG,FAM122A,CNOT6,YWHAZ,TCOF1,RUFY3,CDK2,TSEN15,MRPL3,BCCIP,ZNF207,MMACHC,IMMT,SARNP,GNPNAT1,FOXM1,IVNS1ABP,CHD1L,VTI1A,IRF3,RAD23A,ANKRD28,CSDE1,MRPL50,PRKD3,IARS,AKAP8,EXOSC1,NSFL1C,SOCS6,SCAMP4,CYB5R1,MINPP1,RLIM,CPNE1,NXT1,EID1,TAOK1,MBD3,ERC1,USP36,SRSF1,RAD51C,HSPA4,RBL1,DGCR8,LMBR1,ATF6,COIL,CSNK1D,TUBB,GALK1,RRP15,SRSF6,TCF3,FLOT1,MYNN,ARGLU1,CHAC2,POFUT1,MAD2L2,TFRC,XPR1,KRI1,GART,KLHL20,FJX1,DCP1A,GEMIN6,POLR1B,ORC3,SPTAN1,ADAM17,TK1,NASP,KAT2A,TMEM39A,ILF3,RFXANK,JTB,TBRG4,RABIF,PRMT2,KLF6,TARS,MAPK3,CBX3,GNA12,KEAP1,POLE,DUSP11,BYSL,GCSH,ANAPC4,SNAPIN |
| 4.246e-17 | -37.70 | BENPORATH_PROLIFERATION | MSigDB lists | BENPORATH_PROLIFERATION | 134 | 61 | 17377 | 2626 |
ANKRD27,MRPL9,H2AFZ,C1orf112,CDT1,CENPF,RBM8A,PTTG1,DBF4,RACGAP1,NUF2,AGFG1,ARF1,NCAPG,STMN1,TFRC,PRPF18,SPAG5,DTL,GART,PCNA,PDCD10,SUV39H2,PRC1,MSH2,CENPM,TP53BP2,MND1,PRIM2,FAM49B,CDC123,ASPM,PBK,RAD51AP1,MYBL2,GTPBP4,RRM2,RIT1,PKMYT1,DCUN1D5,ANLN,MCM2,H2AFV,SLC25A5,FANCE,DAP3,SMAD2,ATAD2,BIRC5,CSNK1G1,CDCA5,FAM3C,PROSER1,CEBPG,COX5A,KPNA2,SNRPG,CCNB2,TMEM14A,LRP8,HDAC2 |
| 4.789e-17 | -37.58 | HALLMARK_OXIDATIVE_PHOSPHORYLATION | MSigDB lists | HALLMARK_OXIDATIVE_PHOSPHORYLATION | 182 | 74 | 17377 | 2626 |
NDUFA5,COX15,IMMT,NDUFB6,SUCLG1,MRPS15,UQCR10,MDH2,GLUD1,OAT,SDHA,DECR1,ATP6V0B,GOT2,MRPL34,HADHB,CS,HTRA2,TIMM50,GPX4,ATP6V1G1,IDH3A,VDAC2,NDUFA7,OGDH,NDUFB1,VDAC1,SLC25A5,PDHX,TIMM13,TIMM17A,COX5A,UQCRH,ATP6V0C,ATP6V0E1,NDUFV2,COX5B,NDUFS1,PHB2,SLC25A12,NDUFA4,CYCS,COX4I1,NDUFS7,NDUFS4,NDUFV1,NDUFA2,NDUFB4,NDUFS8,CYC1,MRPL11,NDUFA3,MTX2,LDHB,TIMM8B,NQO2,LDHA,RHOT1,RHOT2,ECH1,CYB5A,MFN2,SDHB,ATP6V1D,PRDX3,COX7A2L,COX8A,LRPPRC,ACAT1,MDH1,ACADM,GPI,ATP6V1C1,IDH3B |
| 4.869e-17 | -37.56 | UBC (ubiquitin C) | protein interactions | 7316 | 1002 | 263 | 17029 | 2761 |
PDCD6IP,H2AFZ,TSC22D3,XIAP,CUL1,PABPC4,PSMD1,RAD23B,AP2B1,PCBP2,LACTB,MKI67,HNRNPF,TOPORS,AURKB,MCM2,ZFAND5,RFC2,EIF3A,STOML2,RAD18,PSMD8,AXIN1,MAP4,MRPL27,OGT,SMAD1,ARRB2,TRAF5,PTOV1,DDX58,HIVEP3,COX5B,RECQL,GGA1,DLGAP4,DHX9,PSEN1,CDC73,NPLOC4,WDR48,RPN1,SLC38A5,ZNRF2,MCM5,FBXO7,FOXN2,MVP,PPP6R1,PPA1,MORC3,SOCS5,RB1CC1,C1orf35,USP10,PLEC,ADRB2,MATR3,MTR,CCT8,NCDN,HMGN2,ACLY,USP32,VCPIP1,TCOF1,CDKN2A,NDC1,ATXN3,UBR2,RAC1,DAZAP2,SDHA,ANKIB1,STAM,GNB2,UCHL5,NSFL1C,CDKN1B,TTC3,ANAPC7,RNF169,CCT2,MAPRE2,RFC3,NBPF11,WBP2,CUL3,DNAJA1,TRIM28,DDX17,CHCHD3,SEC61A1,RNF38,H2AFX,ATF6,TRIM32,FUS,USP13,OTUD5,NDUFS1,ANKRD13D,BABAM1,FLOT1,BRAP,WDR5,HLA-A,WWP2,RPA2,PSMD2,PTEN,HUWE1,LTN1,MAP3K14,HNRNPM,TMEM160,TNFAIP3,ILF3,ADSL,OTUD3,MACF1,RPA1,HGS,KEAP1,ZHX1,KHSRP,ASNA1,PARP10,PURA,DDB1,FAF1,AGRN,CSNK2A1,UBQLN2,USP48,BECN1,MAP1LC3B,BIRC2,KCMF1,DLG5,CDC42,HADHB,JOSD1,NDUFB9,TIMM50,VHL,UBE2V1,BRCA1,USP21,DHX15,OPTN,SEPT1,UEVLD,CHD3,PRPF4,CLU,COPS6,DCAF5,PSMC1,UBE2D3,DNAJB2,UBXN1,NACA,EPN1,DNAJB1,RGS2,ASXL2,SNRNP25,RBM3,ZRANB1,UBE3C,ATP6V0D1,TRAFD1,TSTA3,ERLIN1,PSMA1,CAND1,PSMC4,NAP1L1,SYNCRIP,YWHAZ,RUVBL2,ATP5F1A,RBBP4,RNF114,KCTD7,USP7,CYLD,RPLP2,COPE,SUMO2,PMS2,UCK2,RAD23A,USP5,HNRNPA2B1,FARSA,BABAM2,PSMA6,MDM2,CCDC50,IARS,ABRAXAS2,CYB5R1,RLIM,CHP1,PRPF19,KDM3B,UBQLN4,BIRC3,HPDL,RNF25,PSMB7,TUBGCP5,TOR1AIP2,VDAC1,PEF1,TOLLIP,EIF3H,TMEM201,SRSF1,ATP1A1,IDE,DAP3,TAB2,HNRNPR,PSMD3,CEP55,ANP32E,USP11,SMURF1,AP2S1,TRIP12,RAE1,DCTN2,AGO2,ARF1,NCAPG,TUBGCP2,WRNIP1,HERC3,PTPN2,NDUFS8,ATG13,FBL,RNF5,TXNL1,PHF20L1,ELOVL5,RHOA,ACP2,NASP,TUFM,WDR81,RHOT2,CHCHD6,SNRPA,TRIM26,PLAA,OSBPL8,GLG1,E2F1,UBE2C |
| 5.777e-17 | -37.39 | LINDGREN_BLADDER_CANCER_CLUSTER_3_UP | MSigDB lists | LINDGREN_BLADDER_CANCER_CLUSTER_3_UP | 304 | 104 | 17377 | 2626 |
TMEM106C,ANKRD27,H2AFZ,SUCLG1,POC1A,RAF1,PTTG1,UCK2,TMEM97,RMI2,SIRT2,KIF2C,BCL2L1,ORC1,CCNB1,BRIX1,STMN1,TCF19,KIFC1,CDKN2C,PCNA,KIF14,RNASEH2A,TFG,TACC3,PLK1,RFC3,METTL2A,RRM2,WDHD1,CDC6,GLO1,BRCA1,H2AFV,SERP1,CHAF1A,RAD51C,RAD18,RBL1,CEP55,PPA2,KPNA2,ARRB2,RTN3,NXT2,MAPRE1,DEPDC1,CDT1,CENPF,TRMT6,DBF4,CDCA8,KIF23,RACGAP1,GMCL1,FAM136A,MAD2L2,TFRC,COPB2,SAC3D1,EBP,PDXP,RPN1,MED8,MCM5,MSH2,NAA50,PRC1,DAPK1,KIFAP3,MRPL48,C12orf75,IMPA2,ALDH9A1,ADAM17,TK1,NASP,NQO2,MYBL2,KIF11,TARS,NEU1,PRDX1,RBM38,PSMC4,HMGN2,KPNA4,MTHFD2,ATAD2,BIRC5,TWSG1,ACOX1,PRPS2,DBI,E2F1,FAM83D,HMGB2,ACADM,RBBP4,ATP6V1C1,CDK2,UBE2C,CCNB2,FAF1 |
| 6.505e-17 | -37.27 | HDAC5 (histone deacetylase 5) | protein interactions | 10014 | 351 | 120 | 17029 | 2761 |
USP7,PRKAB1,DDX47,NOP2,SF3B1,MDH2,MYH9,CSNK2A1,GLUD1,OAT,UBE2I,MYEF2,GNB2,SF3B2,HNRNPA2B1,PA2G4,APLP2,ZBTB21,PRKD3,PCNA,PSMD1,ATP2A2,IARS,EIF4A3,GOT2,CS,RPN2,PDIA6,STRAP,PCBP2,CDC5L,PRPF19,CCT2,LARS,SNRNP200,VDAC2,HNRNPF,DDX20,AURKB,DNAJA1,MEF2D,MCM2,VDAC1,TRIM28,DHX15,RPSA,SRSF1,DDX17,PPP2CA,BRMS1,HSPA4,ATP1A1,DDOST,HNRNPR,TAB2,PSMD3,OGT,H3F3A,LTA4H,PPP2R2D,TUBB,NCOR2,PHB2,PRKAA1,TKT,DHX9,MEF2A,ATP5F1B,PRPF39,WDR5,HAUS2,TFRC,COPB2,RPN1,PSMD2,SMC3,HDAC7,MCM5,KIF13B,EFTUD2,AHCY,ALDH18A1,PABPC1,SLC25A1,NUDC,EIF3L,PRKDC,MTA2,RFXANK,TUFM,LDHA,ILF3,PKM,FXR1,CCT8,APPL1,TARS,NEU1,ECH1,PSMC4,XRCC5,TFEB,CAND1,EPRS,UPF1,RBM25,GPS2,PRDX3,RBMX,QARS,ACLY,LRPPRC,ACAT1,YWHAZ,RUVBL2,ATP5F1A,YY1,RBBP4,YWHAH,DDB1 |
| 6.567e-17 | -37.26 | MODULE_198 | MSigDB lists | MODULE_198 | 296 | 102 | 17377 | 2626 |
TCF12,H2AFZ,THOC1,FOXM1,PTTG1,AP3M2,CSNK2A1,KIF2C,ORC1,CCNB1,STMN1,MAPK14,RAD23A,CDKN2C,APLP2,PCNA,ASAP2,CCNA2,MTA1,POP7,NUP107,TRA2B,KIF22,NUP153,DNMT1,SRSF10,SRPK2,SAP30,CDC5L,PLK1,RFC3,HMGN4,E2F3,HNRNPF,POLR2D,SLBP,SMC2,NUTF2,SOX4,RFC2,CHAF1A,SRSF1,PRIM1,DDX17,RAD51C,BRD2,HNRNPR,STK38,TULP3,STAT1,H2AFX,XRCC3,FKBP5,LRP8,COIL,CBX4,RAD51D,HDAC2,ZNF146,SSRP1,PRPF4B,EWSR1,POLR2K,SRSF6,CENPF,DHX9,CTCF,KIF23,BLM,RPA2,PSMD2,MSH2,ANP32A,YBX1,KNTC1,NAP1L4,NASP,PRIM2,PRKDC,MYBL2,ILF3,PTTG1IP,PSMC4,RPA1,XRCC5,DDX23,NAP1L1,POLE,DCK,TFDP1,CEBPG,E2F1,KHSRP,HMGB2,DDX5,RBBP4,CDK2,TAF6,CCNB2,ESPL1,CDKN2A,ADNP2 |
| 7.700e-17 | -37.10 | MCM2 (minichromosome maintenance complex component 2) | protein interactions | 4171 | 923 | 246 | 17029 | 2761 |
CCNC,TXN,H2AFZ,HNRNPAB,TMEM109,MOGS,YTHDF3,CSNK2A1,GLUD1,SND1,SNRPD3,SEC16A,PARK7,PABPC4,FANCI,RPL23A,CALM2,DST,PA2G4,CDC42,TIMM23,DPYSL2,HADHB,AP2B1,TCEA1,TFG,LRRC59,MCMBP,MTPN,PCBP2,TIMM50,SRP72,PLK1,SNRNP200,DPM1,HARS,MKI67,HNRNPF,EZR,CDC6,BRCA1,SOX4,MCM2,SLC25A5,DHX15,ARF4,ASF1B,DPYSL3,AHNAK,FBXO28,CHD3,TONSL,RPS27A,RPS14,PTER,KPNA2,CLU,RPS26,MYL12B,PFKP,CAPN1,SSRP1,FUBP1,UBE2D3,PPIB,HSPH1,EWSR1,PHB2,UBXN1,NACA,PRKAA1,DHX9,RPL15,COPG2,NPLOC4,LMNA,FKBP1A,RPN1,SUB1,SMC3,MCM5,CAPZA1,CTPS1,AHCY,RBM3,MVP,MCPH1,PABPC1,EEF1D,KDELR1,EIF5A,EIF3L,ACSL3,RPS10,PLEC,CAPZA2,PKM,EIF4G2,ABCF1,CCT8,PSMB3,XRCC5,CAND1,DERL1,CAT,MAGED2,NAP1L1,KPNA1,SYNCRIP,TXNDC16,CSK,QARS,RBMX,ACLY,SIAH2,FN3KRP,NUP62,YWHAZ,ATP5F1A,EHD4,MYO9A,CDK2,CCNB2,CDKN2A,MBD1,KARS,RPLP2,UGP2,GNPNAT1,IVNS1ABP,DYNLL1,SF3B1,EIF3D,ACTR3,ANK3,MYH9,ORC1,PCBP1,CPNE3,APP,RPL11,PHC2,CRKL,TERF2IP,HNRNPA2B1,SEC11A,FARSA,RAB21,SIAH1,KIF14,DUT,DDA1,AKAP8,UBA5,CS,TARDBP,RPN2,PDIA6,POC5,CFL1,CCT2,PSMA8,KAT7,CPOX,RPL38,NFATC2,DNAJA1,H2AFV,RPS9,RPSA,MAT2A,DDX17,DNAJC10,DDOST,HNRNPR,TAB2,PSMD3,H2AFX,NCLN,TRIM32,FUS,H3F3A,MAPK1,PPP2R2D,TUBB,TMEM33,MIF,NDUFS1,MCM10,PKP4,CDT1,DBF4,TKT,ATG2B,ABHD14B,SDF2L1,MYO9B,LANCL1,ATP5F1B,MAT2B,FBXO3,RPA2,PSMD2,GART,HUWE1,RPL17,AHSA1,TAGLN2,PTGES3,FBL,RPL22L1,LYPLA2,HNRNPM,SLC25A1,LDHB,MOB4,STAU1,MLEC,PRKDC,TUFM,LDHA,ILF3,TBRG4,ADSL,ATP5MF,RPL27A,MACF1,CDK11A,PICALM,TARS,POLR2A,PRDX1,MAPK3,RPA1,CBX3,PDCD6,RPL32,PRDX3,ACOX1,LRPPRC,KHSRP,DDX5,SPCS3,SRSF3,YWHAH,TERF1 |
| 8.656e-17 | -36.99 | VCAM1 (vascular cell adhesion molecule 1) | protein interactions | 7412 | 454 | 144 | 17029 | 2761 |
SRM,PDCD6IP,NUP188,COPA,AGFG1,SND1,RBM4,EIF4A3,PIK3R2,SRI,DNM2,AP2B1,PCBP2,LARS,SNRNP200,NSUN2,MRPL43,HNRNPF,EZR,ESYT1,MCM2,DHX15,EIF3A,RPS27A,RPS14,ITGB1,ATXN2L,KPNA2,ACTB,CAPN1,SSRP1,FUBP1,EWSR1,MAPRE1,PHB2,DHX9,TIA1,EPN1,NUP205,LMNA,RPN1,VASP,MCM5,EFTUD2,CAPZA1,PABPC1,EEF1D,EIF3L,NTPCR,SF3B6,RPS10,GTPBP4,RPS24,PLEC,CCT8,XRCC5,RPL36,SEC31A,EPRS,SYNCRIP,RBMX,ARAP1,YWHAZ,RUVBL2,ATP5F1A,SNRNP70,IMMT,MDH2,EIF3D,SLC2A1,RAC1,MYH9,PCBP1,STMN1,GLRX3,RPL11,HNRNPA2B1,DECR1,PSMA6,IARS,SEPT11,TARDBP,TALDO1,STRAP,CFL1,CCT2,RPL35,SEC61B,RPL38,VDAC2,VDAC1,TRIM28,RPS9,RPSA,DDX17,PPP2CA,AFDN,HNRNPR,CORO1C,PSMD3,CHMP4B,FUS,AP2S1,TUBB,MIF,NDUFS1,RPS2,ARF1,ATP5F1B,CSNK1A1,TFRC,FERMT3,PSMD2,PDCD10,RPL17,PTPN11,TAGLN2,FBL,UBE2M,LYPLA2,HNRNPM,LDHB,PRKDC,RPL8,ILF3,LDHA,TUFM,RPL27A,MACF1,PICALM,TARS,PRDX1,SMAP2,HSPA1B,UPF1,PDCD6,PRDX3,SNAP29,HNRNPH3,LRPPRC,KHSRP,ACAT1,DDX5,BYSL |
| 9.936e-17 | -36.85 | RHEIN_ALL_GLUCOCORTICOID_THERAPY_DN | MSigDB lists | RHEIN_ALL_GLUCOCORTICOID_THERAPY_DN | 345 | 113 | 17377 | 2626 |
BCCIP,TCF12,ST13,UGP2,IVNS1ABP,DYNLL1,MAGED1,PTTG1,RBM8A,OLA1,TMEM97,SNRPD3,STMN1,PARK7,BCAP31,CPNE3,SSR1,FANCL,PCNA,ASAP2,PSMA6,GOT2,DPYSL2,DUT,PDCD2,SEPT11,AHCYL1,TALDO1,SPTSSA,PDIA6,HMGN4,EID1,RAD51AP1,KIF15,PSMG1,RRM2,NUSAP1,GLO1,SMC2,MCM2,VDAC1,SHCBP1,PSMB9,PRPSAP1,CLNS1A,STOML2,PRIM1,CHCHD3,CEP55,IARS2,ANP32E,COPS6,LTA4H,RTN3,TUBB,SSRP1,MIF,TKT,RRM1,RACGAP1,HAUS4,NCAPG,BZW2,HDDC2,MCTS1,DTL,DAD1,MCM5,ATIC,PRC1,ANP32A,AHCY,BCL2,CREB1,FBL,CITED2,PPA1,LDHB,CYFIP1,RHOA,NASP,PRKDC,METTL5,TUFM,LDHA,ADSL,DCTD,FXR1,KIF11,CCT8,CYB5A,PRDX1,RPA1,HMGN2,CAT,EPRS,NAP1L1,PDLIM1,BIRC5,PRDX3,RBMX,PRPS2,LRPPRC,ACAT1,PKD2,MDH1,ACADM,GPI,RBBP4,TMEM14A,CCNB2,MRPL3,GCSH |
| 1.099e-16 | -36.75 | DLD (dihydrolipoamide dehydrogenase) | protein interactions | 1738 | 374 | 125 | 17029 | 2761 |
PDCD6IP,TXN,COPA,DYNLL1,EIF3D,COPE,UCK2,OLA1,SND1,AP1B1,OAT,SDHA,PARK7,FARSA,TNFAIP8,IARS,CDC42,SAR1A,EIF4A3,SIAH1,CD3EAP,ATG3,AP1M1,SUCLG2,TTC4,CLTB,PDIA6,ATF2,SMARCE1,STRAP,PDCL3,CDC37,CSTF1,PRPF19,SRP72,COPS8,CCT2,LARS,IDH3A,DNAJA1,PITPNB,OGDH,RAB1A,H2AFV,EIF3G,PDHX,TRIM28,ARF4,MAT2A,EIF3A,STOML2,SUPT16H,EIF3K,DAP3,HSPA4,TIMM13,PSMD3,PPM1G,DHTKD1,FUS,MRPL13,PSMC1,MIF,GALK1,HSPH1,MRPL9,MRPL42,NACA,THRAP3,ARF1,AP3S1,RAB11A,SRRT,RPA2,ERH,PSMD2,SUB1,SMC3,GART,HUWE1,BANF1,RTCB,NAA50,H2AFY,ANP32A,COPS7B,PTGES3,FBL,MRPL11,PABPC1,PPA1,UBE2M,EEF1D,NUDC,LDHB,SNX2,PSPC1,SF3B6,LDHA,RANGAP1,BCLAF1,SEPT7,TOMM40,API5,MAP2K2,CCT8,PSMC4,RPA1,XRCC5,DDX23,SDHB,EPRS,FBXO21,NAP1L1,MTHFD2,PRDX3,QARS,SIAH2,ACAT1,YWHAZ,RUVBL2,RBBP4,PGAM1,YWHAH,ZC3HAV1 |
| 1.325e-16 | -36.56 | ZHANG_BREAST_CANCER_PROGENITORS_UP | MSigDB lists | ZHANG_BREAST_CANCER_PROGENITORS_UP | 395 | 124 | 17377 | 2626 |
FGFR1OP,H2AFZ,MPHOSPH8,STARD7,KIF2C,STMN1,POLR3K,PARK7,UBLCP1,PAIP2,ARL6IP6,HNRNPA2B1,ANKRD26,CCNA2,STRBP,NVL,UCHL5,PIN1,TTC9C,NUP107,PDS5B,TTC3,BCAP29,TCEA1,NFU1,FAM76B,METTL9,ZNF770,STRAP,FGFR1OP2,SRSF10,SAP30,USP34,ANKLE2,SNRNP200,NRAS,HARS,EID1,PBK,IDH3A,LRBA,RRM2,DNAJC9,ATXN1,NUP155,CDC6,BRCA1,DNAJA1,SMC2,ANLN,MCM2,VDAC1,SHCBP1,PRIM1,TAF2,ZNF317,WDR11,ACYP1,RBL1,VPS26B,TIMM17A,ZNF367,TULP3,CEP55,ANP32E,POT1,SMNDC1,TMEM33,SEPHS2,C1orf74,EWSR1,CDC40,PKP4,DEPDC1,ZCCHC8,PHB2,C1orf112,TRMT6,CENPF,DBF4,CDCA8,RPL15,CTCF,NDUFA4,NCAPG,CDC73,TFRC,NDUFS4,PHF14,EFTUD2,GEMIN6,BRD7,AHCY,BCL2,GTF2H2,NUP85,N4BP2,SMC4,MOB4,PSPC1,ACSL3,UTP15,ILF3,CAPZA2,EIF4H,MATR3,PHF6,RPA1,XRCC5,NEK1,PCM1,C1orf131,ATAD2,SYNCRIP,DCK,PRPS2,HMGB2,MDH1,DUSP11,CNOT6,ZRANB2,SRSF3,NANP,SNAPIN |
| 1.482e-16 | -36.45 | ONKEN_UVEAL_MELANOMA_UP | MSigDB lists | ONKEN_UVEAL_MELANOMA_UP | 728 | 194 | 17377 | 2626 |
CCDC93,ZBTB10,PNISR,PLXNC1,NF1,HMGXB3,YTHDF3,PTP4A3,NENF,NANS,LACTB2,USP48,SLC20A1,MRPL19,CREM,DLG5,ASAP2,PCNA,RABGAP1L,CDC25B,TCEA1,VPS13B,COPS8,LAP3,SREK1,GALNT7,CBFB,PLEKHF2,MAN2A2,ANKRD10,CHD3,LUC7L3,TPP2,OGT,BAZ1B,ACTB,KPNA2,TRAF5,MRPL13,PFKP,ANXA11,NUMB,PTOV1,HSPH1,RECQL,PARP12,PPP1R12A,POLR2K,HLA-E,TRIO,TIA1,TMEM165,FKBP1A,GNS,MEX3C,MBD2,DAPK1,FBXL7,MRPL40,CYC1,LUC7L2,ABCC1,VOPP1,SRSF11,ZNF84,TSTA3,RB1CC1,AACS,TSPAN31,DCAF8,OXR1,MAP4K3,NFATC2IP,MTX1,LY6E,MTR,ISG15,RHOB,ANKRD46,RDH11,GNAS,DERL1,RBM25,CDC27,SYNCRIP,TMEM168,ETS2,PDLIM1,ORMDL2,NFIL3,ACLY,YWHAZ,RUFY3,PTDSS1,RNF139,TCF12,GGNBP2,NQO1,TOR1AIP1,KIAA0232,ACTR3,SMARCA4,NIPA2,POMP,ZNF267,HCFC1R1,LYN,SAFB2,SDHA,CPNE3,APP,STAM,DECR1,RRN3,CCNA2,SHC1,TNFAIP8,IARS,ATP2A2,KIF14,ADCY9,TTC3,SCAMP4,SAP30,EBAG9,TIMP2,PSRC1,WIPF1,HTATIP2,PFKFB3,NUSAP1,CADM1,BICD2,PSMB9,RAD54B,SUPT16H,AMZ2,TAF2,DNAJC10,IDE,CDC16,CERS6,UBXN2B,STAT6,STAT1,H2AFX,AP1S1,RBMS1,ANP32E,SNRPG,PDXK,LRP8,ATMIN,PRPF4B,ADAM23,DNAJC2,DAP,GTF3A,MFSD10,PTPN2,GOLM1,CAPN2,CTSS,CLIC4,SLC1A4,RPL17,GEMIN6,TAGLN2,SGCB,SLC35A1,NCOA2,S100A6,SPTAN1,PHF20L1,ADAM17,NASP,FAM49B,PRKDC,BTAF1,PSPC1,EMP3,RHOT1,DDX39A,MACF1,HLA-B,SGSH,PKD2,HMGB2,PSAP,ATP6V1C1,PLOD3,PGAM1,TERF1,IFI16 |
| 1.534e-16 | -36.41 | MORF_SKP1A | MSigDB lists | MORF_SKP1A | 193 | 76 | 17377 | 2626 |
NDUFA5,RAB14,KARS,H2AFZ,HNRNPAB,RAC1,SUMO2,COPE,ENSA,STARD7,PARK7,BCAP31,MBD4,RAD23A,SF3B2,CALM2,UTP18,RAD23B,PPP6C,HADHB,EBAG9,CCT2,SNRNP200,CDC123,TLK1,GMFB,WBP2,TRIM28,RHEB,KIF2A,PSMD8,PPM1G,COX5A,ATP6V0C,KPNA2,SNRPG,BTF3,PSMC1,AP2S1,COIL,MYL12B,NDUFV2,NDUFS1,MRPL9,PDAP1,DAP,NACA,DCTN2,CTCF,COX4I1,UBE4A,PSMD9,NDUFV1,NDUFA2,BANF1,BUD31,CYC1,MAML1,TMED2,EEF1D,HMGN1,NSDHL,ILF3,JTB,SSR2,EIF4H,CBX3,HGS,PDCD6,RBMX,COX7A2L,YWHAZ,MDH1,SRSF3,WIPI2,YY1 |
| 1.767e-16 | -36.27 | GSE16385_MONOCYTE_VS_12H_ROSIGLITAZONE_TREATED_MACROPHAGE_DN | MSigDB lists | GSE16385_MONOCYTE_VS_12H_ROSIGLITAZONE_TREATED_MACROPHAGE_DN | 178 | 72 | 17377 | 2626 |
COX15,TMED7,MRPS15,TMX4,OLA1,C5orf30,GYG1,GGPS1,TERF2IP,IMPAD1,MRPS27,CS,SPTSSA,FGFR1OP2,CLCN3,PSRC1,KLF10,EID1,PCGF6,WDR82,MCFD2,PRKRA,GFER,RPS9,PDHX,C1orf122,IWS1,PDRG1,TAB2,UEVLD,CHCHD1,ADAM9,VPS4A,COIL,SMAD4,ZNF146,HDAC2,RMND5A,MZT1,MRPL9,TOR3A,TRMT6,GMCL1,PITHD1,HAUS2,PNO1,RRP36,ZBTB45,TNPO3,YBX1,GLE1,PIK3IP1,TSHZ1,DDX28,FAM133B,PPWD1,PTTG1IP,EIF4H,CCT8,TARS,ANKRD46,PFDN5,ZNF777,KPNA4,C4orf46,SLC16A1,VCPIP1,WDR76,RBPJ,NANP,YY1,RNF114 |
| 1.840e-16 | -36.23 | gag (Pr55(Gag)) | protein interactions | 155030 | 968 | 254 | 17029 | 2761 |
PDCD6IP,HNRNPAB,COPA,ADAM10,TRIM11,MCCC1,AP3M2,MOGS,YTHDF3,CSNK2A1,TGOLN2,SND1,CDIPT,OAT,UBE2I,MAP1LC3B,BECN1,PABPC4,SF3B2,KRR1,PRNP,CDK5,CALM2,RAB8A,RAP1A,EIF4A3,AP3S2,SRSF4,AP1M1,SRI,DNM2,AP2B1,TRA2B,NUP153,EIF5,LRRC59,SRSF10,CDC5L,NOL12,SRP72,PLK1,LARS,SNRNP200,RBX1,AKT2,NSUN2,MKI67,HNRNPF,EZR,UBE2V1,NUTF2,SLC25A5,DHX15,ARF4,EIF3A,EPB41,GEMIN5,AHNAK,CHD3,PPM1G,MAP4,ATXN2L,KPNA2,ACTB,ROCK1,VPS4A,PPIB,DNAJC5,PPP1R12A,PHB2,GGA1,SDC2,DHX9,TOP2B,CDK13,THRAP3,DNAJB1,RLF,VPS25,CFLAR,CD59,RPN1,HDAC7,BANF1,TNPO3,YBX1,ALDH18A1,LRSAM1,ATP6V0D1,PABPC1,SYTL3,LUC7L2,EEF1D,APOL1,DDX28,PRRC2A,ACSL3,RPL6,SRSF5,PKM,FXR1,MAP2K2,MATR3,CCT8,NMT2,ISG15,PI4K2A,XRCC5,FAS,EPRS,NAP1L1,FNTA,KPNA1,SYNCRIP,NSF,CSNK1G1,QARS,RBMX,ACLY,TCOF1,ATP5F1A,RUVBL2,PTDSS1,NRBP1,ZC3HAV1,WASF2,CHMP2A,SART1,KARS,CYLD,IVNS1ABP,DYNLL1,SF3B1,EIF3D,ACTR3,RAC1,UCK2,OLA1,MYH9,IRF3,BCL2L1,PRKACA,PCBP1,CPNE3,RPL11,CSDE1,HNRNPA2B1,SHC1,IARS,PIN1,TARDBP,CLTB,RBM15,STRAP,CFL1,ACSL5,PPIF,CCT2,RPL29,RPL35,CGAS,RAB7A,IDH3A,SELPLG,PPIE,HTATIP2,NUP155,DNAJA1,CHMP2B,TOLLIP,TRIM28,RPS9,SRSF1,DDX17,AFDN,PPP2CA,CHMP4A,ATP1A1,HSPA4,PPP2R5A,SEC61A1,DDOST,JAK1,HNRNPR,TAB2,SAFB,STAT1,CHMP4B,NCOA1,MAPK1,AP2S1,ABCA1,DYNC1LI2,TUBB,INTS2,NIFK,RPS2,PDAP1,SRSF6,AGO2,DCTN2,FLOT1,NKRF,ARF1,GGA2,HDGFL2,AP3S1,RAB11A,TFRC,HLA-A,RBM17,KIF5B,PSMD2,PTEN,RPL17,ARF5,DCP1A,ANXA5,RPL19,CREB1,MRPL11,STAT3,HNRNPM,RBM15B,SPTAN1,LDHB,TGFB1,PPAN,STAU1,RHOA,PRKDC,PRKAR1B,LDHA,RPL8,ILF3,PACS1,RPL27A,TARS,ZFR,HSPA1B,MAPK3,DDX23,HLA-B,HGS,KPNA4,UPF1,HNRNPH3,LRPPRC,LY75,KHSRP,DDX5,CD81,IFI16,DDX52 |
| 1.841e-16 | -36.23 | MORF_CTBP1 | MSigDB lists | MORF_CTBP1 | 163 | 68 | 17377 | 2626 |
KARS,HNRNPAB,ADD1,DYNLL1,SUMO2,STARD7,AP1B1,DAZAP2,UBE2I,GNB2,PARK7,MBD4,RAD23A,SF3B2,PIN1,HADHB,TARDBP,PCBP2,CCT2,SNRNP200,VDAC2,RNPS1,GMFB,PSMB7,H2AFV,EIF3H,RHEB,EIF3K,DAP3,PIEZO1,BTF3,COPS6,COX5B,MRPL9,NACA,COX4I1,XPO7,AP3S1,NDUFS4,RPN1,DNAJC8,NDUFV1,NDUFA2,CAPZA1,CYC1,LYPLA2,TMED2,HMGN1,POLR2I,RHOA,WDR1,JTB,SSR2,FBXO9,EIF4G2,EIF4H,DDX39A,CBX3,XRCC5,FNTA,CSK,SETD3,ACLY,IMPDH1,YWHAZ,MDH1,IDH3B,SNRNP70 |
| 1.879e-16 | -36.21 | GSE22886_NAIVE_TCELL_VS_NEUTROPHIL_UP | MSigDB lists | GSE22886_NAIVE_TCELL_VS_NEUTROPHIL_UP | 182 | 73 | 17377 | 2626 |
ZNF207,KARS,EIF3D,YTHDC2,PAIP1,RPL11,MOAP1,NUP210,GRSF1,DUT,AKR1B1,FBXW2,SUCLG2,TRA2B,TTC3,TCEA1,SMARCE1,STRAP,CCT2,LARS,MAPRE2,VDAC2,PSMB7,DNAJC9,GLO1,UTP3,TMEM147,SLC25A5,GLOD4,IARS2,CCDC59,PRPF4B,MIF,C9orf78,NDUFV2,PHB2,SRSF6,UFC1,GTF3A,HMGN3,SUPT7L,LRRC8D,BANF1,FBXO7,PTPN11,BRD7,YBX1,MDFIC,NUP85,HNRNPM,NAGPA,EIF3L,HMGN1,TSPYL4,GTPBP4,TUFM,PSMA1,EIF2AK1,DDX39A,CCT8,SNRPA,RPA1,FBXO21,NAP1L1,SGSH,QARS,ERGIC3,LRPPRC,ACAT1,SRSF3,GPI,IDH3B,CD81 |
| 2.142e-16 | -36.08 | MILI_PSEUDOPODIA_HAPTOTAXIS_UP | MSigDB lists | MILI_PSEUDOPODIA_HAPTOTAXIS_UP | 475 | 141 | 17377 | 2626 |
CCNC,ST13,THOC1,YTHDF3,AGFG1,MYEF2,UBLCP1,KRR1,RAP1A,FBXW2,RPF2,TRA2B,CISD2,RP2,TCEA1,MTPN,FGFR1OP2,CDC5L,RYBP,FYTTD1,GMFB,TOPORS,PBRM1,MAK16,PRIM1,IWS1,ATE1,ROCK1,BEND6,MRPL13,CHPT1,DCAF5,HDAC2,NXT2,UBE2D3,TBC1D12,PPP1R12A,MEF2A,DOCK11,NDUFS4,SMC3,EIF2S2,ZNRF2,RBM34,ZNF326,CSNK1G3,SRSF11,CYFIP1,AGGF1,ZMYND11,OXR1,GTPBP4,KRAS,EXOSC9,BCLAF1,FAM133B,EIF2A,CAPZA2,SEPT7,FXR1,EIF4G2,SLTM,MATR3,TWISTNB,MBIP,NAP1L1,RBM25,SNAP23,PTAR1,VCPIP1,TIGD2,TCF12,SARNP,UGP2,RWDD1,GNPNAT1,IVNS1ABP,SF3B1,OLA1,COMMD8,PAIP1,UBXN2A,STRBP,UCHL5,ANKRD13C,ATF2,ARL5A,CDK12,STRAP,CUL3,MTMR6,NUSAP1,DNAJA1,CHMP2B,MRPS14,FKBP3,BTBD1,SRSF1,KIF2A,HNRNPR,DYNC1LI2,PKP4,SMAP1,NUP54,HMGN3,PIP4K2A,RAB11A,PNO1,KIF5B,PTPN2,PDCD10,RPL17,TANK,NAA50,BTF3L4,LTN1,ORC3,MYO5A,NCOA2,TXNL1,YTHDC1,MOB4,PPP3CA,GTF3C6,DCAF6,TCTEX1D2,NET1,PARP4,CCDC34,PPWD1,TTC33,SH3GLB1,ZFR,ATP6V1D,HNRNPH3,DDX5,ZRANB2,SRSF3,IFI16,GPATCH4,ANAPC4 |
| 2.145e-16 | -36.08 | MARSON_BOUND_BY_FOXP3_STIMULATED | MSigDB lists | MARSON_BOUND_BY_FOXP3_STIMULATED | 938 | 235 | 17377 | 2626 |
UBL3,NAT9,LYRM4,H2AFZ,TXN,ST13,ADD1,ADAM10,YTHDF3,KIF2C,USP48,IKBIP,SLC20A1,SYNRG,SNAPC4,PARK7,USF1,RAP1A,NUP210,GOT2,DPYSL2,RABGAP1L,HADHB,JOSD1,ZBTB22,NUP153,CISD2,EIF5,TIPARP,SENP1,DRAM2,SRPK2,FYTTD1,ORAI2,ERCC1,APH1A,ZBED5,HNRNPF,MCL1,ARHGDIB,UBE2V1,BRCA1,PBRM1,ZFAND5,STX16,RHEB,EIF4ENIF1,TMED10,OGT,CAB39,RPS26,RTN3,OAZ1,SLC25A33,FUBP1,WSB2,UBE2D3,C1orf74,HSPH1,NDUFV2,GMFG,C16orf87,NCKAP1,XPNPEP3,RGS2,PSEN1,FBRS,DTL,FAM192A,FKBP1A,RNF121,SNRNP25,C1GALT1,NFATC3,ZNRF2,LRRC8D,SSBP3,XPA,PPP4R1,PIKFYVE,TMED2,HP1BP3,ABHD2,AGGF1,ETV3,MAPKAPK3,PRRC2A,KCTD20,USP10,FAM133B,ARID1A,ARMC8,PSMB3,BBS12,SCARB2,SERF2,CDC27,CSK,SIL1,MAP3K5,C11orf1,NRBP1,ZC3HAV1,FAM72A,RHOG,WASF2,CYTIP,ASH1L,CYLD,GGNBP2,MPHOSPH8,ZBTB37,CHD1L,TOR1AIP1,SLC2A1,ZADH2,CHD1,PAIP2,ARL6IP6,FLAD1,APLP2,MDM2,SHC1,WDR44,DUT,DDA1,NSFL1C,MRPL34,PDCD2,CDKN1B,INTS12,AHCYL1,POU2AF1,MAPRE2,BIRC3,PPT1,EID1,COQ10B,OAF,LYRM1,MAP4K4,PPIE,CUL3,ATP6V0A1,ATXN1,TOR1AIP2,GLO1,NFATC2,DCLRE1C,GSTCD,HERPUD2,TOLLIP,ARL5B,POLG2,EML4,SRSF1,AMZ2,DAP3,PPP2R5A,RBL1,TAB2,STAT6,GADD45B,WDR59,CHMP4B,XRCC4,EYA2,DNAJC2,CDC40,GOLPH3L,MRPL42,SLC41A1,DAP,SRGN,DBF4,FLOT1,CHIC2,SLC25A12,LETMD1,MYNN,JMJD6,ETS1,PMVK,POFUT1,HMG20A,BZW2,RGS1,SRXN1,MAT2B,KIF5B,DNAJC8,SLC35B4,FEM1B,COPS7B,UBE3B,NAP1L4,CREB1,CITED2,TTLL12,CNOT6L,STAT3,FRMD8,S100A6,LYPLA2,CAMK2G,TSHZ1,SAMD4B,CSNK1G2,ELOVL5,GTF3C6,ACP2,RHOA,MLEC,NASP,NEK7,DENND1B,MIER1,METTL5,SCFD2,FBXO9,ARHGEF12,DDX39A,KLF6,PICALM,SMAP2,PRDX1,CBX3,OSBPL8,ZNF330,MAPK6,RBPJ,SRSF3,PARP10,IFI16,FAF1 |
| 2.216e-16 | -36.05 | GO_NUCLEAR_TRANSPORT | MSigDB lists | GO_NUCLEAR_TRANSPORT | 344 | 112 | 17377 | 2626 |
POLA2,RHOG,RAB14,SARNP,NUP188,TSC2,THOC1,RAB11B,RBM8A,ALKBH5,AGFG1,SNRPD3,RPAIN,FBXO22,CDK5,HNRNPA2B1,RAB21,RAB8A,RAP1A,SNUPN,NUP210,EIF4A3,NSRP1,RALB,RAB35,SRSF4,RAB4A,NUP107,NOC2L,TNPO2,NUP153,AHCYL1,CHTOP,F2R,ZC3H3,SEH1L,SRSF10,FYTTD1,SEC61B,NXT1,SNRPB,RAB7A,RNPS1,POLR2D,SLBP,DDX20,HTATIP2,ATXN1,NUP155,NUTF2,RAB1A,BUD13,RAB5B,LSG1,RAB22A,RPSA,RAB2B,SRSF1,GEMIN5,HHEX,RAB24,ARNTL,KPNA2,SNRPG,RRS1,MAPK1,SMURF1,NMD3,AAAS,GEMIN7,RPS15,CDC40,PHB2,SRSF6,RAE1,RAB23,NUP54,RAB6A,XPO7,RAB11A,NUP205,LMNA,BANF1,GEMIN6,TNPO3,ANP32A,UPF2,GEMIN4,GLE1,STAT3,NUP85,RBM15B,TGFB1,EIF5A,SRSF11,PPP3CA,KRAS,SRSF5,RIT1,PTTG1IP,DDX39A,MAPK3,RAB18,TSC1,KPNA4,KPNA1,UPF1,PML,NUP62,SRSF3,TOB1,IPO4 |
| 2.403e-16 | -35.96 | EGFR (epidermal growth factor receptor) | protein interactions | 1956 | 1227 | 306 | 17029 | 2761 |
PDCD6IP,TXN,XIAP,OAT,CDK5,PSMD1,AP1M1,DNM2,AP2B1,TRA2B,NUP153,MAST2,SPATC1L,USP34,ERCC1,AKT2,NSUN2,MRPL43,DDX20,SMC2,ARF4,PRIM1,AHNAK,WAS,STT3A,LUC7L3,MAP4,PTPN7,ITGB1,MPV17,ARRB2,OAZ1,PFKP,AAAS,SSRP1,PPIB,MRPL9,EWSR1,PRKAA1,VAV2,DHX9,DNAAF5,PDXDC1,LMNA,CD59,RPN1,CEP104,SMC3,HDAC7,ATIC,TNPO3,GEMIN4,GNAI2,MRM3,PPP6R1,NUP85,SOCS5,FDFT1,CARS2,SRSF11,COQ8A,BCLAF1,PLEC,MAP2K2,MATR3,NCDN,HMGN2,XRCC5,FAS,PTPRF,DERL1,MAGED2,EPRS,NSF,CSK,DUSP3,MDH1,TCOF1,WIPI2,TMEM159,ZC3HAV1,EXOC3,RWDD1,RAF1,UROD,TMEM97,MYH9,AP1B1,C2orf49,PRKACA,APP,GNB2,CRKL,SPINDOC,SHC1,ATP2A2,SOCS6,TNPO2,ILKAP,TMBIM1,CFL1,SEC61B,RFC3,IDH3A,WBP2,RPL38,CIRBP,PFKFB3,ELP4,DNAJA1,RAB1A,TRIM28,SOCS7,EIF3K,CHCHD3,CHMP4A,HSPA4,SEC61A1,JAK1,TBL3,STAT1,LMBR1,SEL1L,H2AFX,NCLN,FUS,PPP5C,LRP8,TUBB,NDUFS1,ANKRD13D,SCAMP3,SDF2L1,LANCL1,BLM,FOXO3,HLA-A,PNO1,RPA2,PSMD2,PTEN,HUWE1,RPL17,AHSA1,PTPN11,GEMIN6,LTN1,MAP3K14,CNPY3,MOB4,ILF3,TBRG4,KCNQ1,PICALM,CIP2A,PRDX1,POLR2A,RPA1,PLD3,HGS,KEAP1,MFAP1,PML,LRPPRC,HMGB2,DDX5,IPO4,NPHP4,DDX47,COPA,NF1,AAMDC,CSNK2A1,CDIPT,MAPK14,SEC16A,BIRC2,ABL2,CMSS1,PCNA,THADA,TIMM23,PIK3R2,HADHB,ZBTB22,TECR,TIMM50,PTPRK,CDC37,PLK1,PTPN18,DPM1,NCK1,EZR,EPB41,E2F4,SOCS4,ACTB,CLU,NGLY1,NUMB,RPS15,EPN1,CDK13,PPP3CB,RGS2,XPO7,SUB1,TNS3,YBX1,LRSAM1,SLC12A2,NTPCR,TRAFD1,SUGP2,UTP15,RPL6,KRAS,EIF4G2,ARMC8,APPL1,GNAS,RBM25,EXOC4,FN3KRP,PITPNA,YWHAZ,RUVBL2,ATP5F1A,MYO9A,EHD4,ECPAS,BCCIP,IMMT,RPLP2,TOR1AIP1,UCK2,TM9SF3,ZFYVE21,LYN,VAV1,FARSA,BABAM2,IARS,CCDC50,PPP6C,STRAP,RLIM,BIRC3,PON2,ATP1A1,DHX16,AP1S1,REEP4,MAPK1,ABCA1,AP2S1,MIF,GCLM,NADSYN1,SH2D3A,PDAP1,DCTN2,SCYL1,AP3S1,CSNK1A1,NCAPG,BZW2,TUBGCP2,SCYL2,TFRC,PTPN2,GSTK1,GRK2,PELO,NABP2,ARHGEF2,PTGES3,FBL,STAT3,CAMK2G,TELO2,COA3,RPRD1A,CSRP1,SNX2,BTAF1,PRKDC,PSPC1,ABCF2,MIER1,PRKAR1B,TUFM,COG1,RANGAP1,API5,TARS,ZFR,HSPA1B,CNOT9,HLA-B,RAB18,PLAA,KBTBD7,PGRMC1,IDH3B |
| 2.525e-16 | -35.92 | GSE18893_TCONV_VS_TREG_24H_TNF_STIM_UP | MSigDB lists | GSE18893_TCONV_VS_TREG_24H_TNF_STIM_UP | 179 | 72 | 17377 | 2626 |
POLA2,H2AFZ,MRPL39,PTTG1,TMEM97,NIT2,C19orf48,TCF19,PCNA,GOT2,DUT,PPCDC,NDUFB9,RNASEH2A,CABLES2,RNF26,PSRC1,EID1,RAD51AP1,MRPL12,KIF15,NUP155,CDC6,BRCA1,DCUN1D5,CDC23,MCM2,CCNF,RFC2,GFER,BOLA3,NSMCE2,PPA2,MPV17,H2AFX,BTF3,CHID1,TUBB,BCL2L12,PKP4,CHTF18,CUTA,CDT1,DBF4,RRM1,CDCA3,CHCHD2,RACGAP1,VPS25,TFRC,FBXO5,EXOSC7,NDUFA2,CENPJ,MSH2,KNTC1,CYC1,TTLL12,MSH6,GINS1,PRIM2,PRKDC,MYBL2,CCDC34,BORA,SDHB,C1orf131,CDCA5,ERGIC3,COX8A,E2F1,CDK2 |
| 2.771e-16 | -35.82 | enzyme binding | molecular function | GO:0019899 | 2219 | 475 | 17224 | 2647 |
FGFR1OP,TSC2,KDM4A,ADAM10,PRKCSH,CUL1,CCNB1,UBE2I,RIC1,PARK7,CDKN2C,CALM2,PA2G4,USF1,ASAP2,PSMD1,NEK6,RABGAP1L,FIZ1,RAB4A,DNM2,CRY2,MAST2,ECD,CDC25B,PCBP2,RHOBTB3,DDX20,WDHD1,TOPORS,MIER2,AURKB,DCUN1D5,NUTF2,USP22,MCM2,SLC25A5,RFC2,ARF4,STOML2,BRMS1,SMAD2,WAS,RAD18,RPS27A,AXIN1,ITGB1,ATP6V0C,SMAD1,TRAF5,ARRB2,SLF1,LONP2,HDAC2,SVIP,DDX58,PPIB,MAPRE1,GGA1,RHOC,CCZ1,TRIO,VAV2,CUTA,DHX9,ACAP1,STRN4,TOP2B,PARN,CDC73,NPLOC4,DDRGK1,CFLAR,RTKN,TFAP4,RIMS3,HDAC7,FBXO7,ZNF326,MSH2,ATP6V0A2,PIK3IP1,MVP,PHKG2,PPP6R1,SYTL3,LUC7L2,TERF2,SOCS5,CYFIP1,ETV3,MAPKAPK3,RB1CC1,ARMT1,UHRF1BP1,ADRB2,RHOB,CYB5A,PHF6,FAS,XRCC5,DERL1,CAT,EPRS,SCARB2,HSPBP1,FNTA,GOLGA2,NSF,CSK,DUSP3,QARS,FAM83D,PPP3R1,APPL2,ARAP1,PIAS2,GPI,TCOF1,PPP6R3,MAP3K5,RNF14,PDLIM5,RNF139,ALS2,CDKN2A,EGLN1,RHOG,ANKRD27,ATXN3,RAF1,RAC1,WDTC1,TPX2,TBC1D13,BCL2L1,AP1B1,DAZAP2,PRKACA,GLRX3,ANKIB1,STAM,CPNE3,APP,GNB2,MOAP1,TERF2IP,CCNA2,ATP2A2,SHC1,SP100,SH3BP1,TBC1D22A,RALB,MTMR4,TBC1D14,TNPO2,CDKN1B,ANAPC7,MAVS,RNF19A,ATF2,RPRD1B,CDK12,DCTN1,ATP6V1G1,ANKLE2,CCT2,SHOC2,SEC61B,BRD4,EID1,CUL3,ATP6V0A1,ELP4,DNAJA1,MEF2D,TRIM28,ERC1,CHCHD3,PEX5,CHMP4A,HINT1,PPP2R5A,JAK1,CORO1C,STAT1,H2AFX,ATF6,TICAM1,TUBB,USP13,NCOR2,RPS2,SCAMP3,TWNK,TCF3,FLOT1,SIKE1,SDF2L1,SPDL1,FOXO3,MAD2L2,JAKMIP1,GTF2F1,CCNK,MAT2B,PPP1R3B,RPA2,PDCD10,PTEN,CENPJ,PRDM4,ARHGEF1,PTPN11,PRC1,AXIN2,CITED2,CREB1,UBE2M,SPTAN1,PDPK1,PPP3CA,TNFAIP3,KAT2A,LONRF3,STRIP1,NET1,DENND1B,DENND4C,RFXANK,PARP4,JTB,RABIF,ANAPC2,KCNQ1,RAB3IP,ZP3,KIF11,PDE3B,PICALM,POLR2A,FADD,SMAP2,CBX3,INF2,TMEM127,HGS,PRDX3,MAPK6,PML,LRPPRC,PPP1R11,DDX5,RGL1,YWHAH,IGBP1,THAP5,ANAPC4,FAF1,IPO4,KMT2E,PHRF1,YTHDC2,ENSA,UBE2Z,AGFG1,SIRT2,SNRPD3,MAPK14,BECN1,MAP1LC3B,GIT2,FANCI,PRNP,FANCL,RAB8A,PCNA,RAP1A,CDC42,GOT2,ZNHIT6,ATG3,PIK3R2,SRI,PPP1R12C,CDC37,WDR41,PTPRK,ELOF1,PLK1,TRAPPC13,RBX1,NCK1,VHL,EZR,CDC6,UBE2V1,ARHGDIB,BRCA1,ANLN,PRKRA,RHEB,OPTN,PAF1,TBC1D17,ARRDC1,ADAM9,CAB39,KPNA2,ACTB,CHEK2,ROCK1,DVL1,CLU,POT1,SLC12A7,TBC1D12,PPP1R12A,UBXN1,NKD2,CIB1,LAMTOR3,MEF2A,CDK13,RACGAP1,NCKAP1,DNAJB1,PPP3CB,DOCK11,XPO7,RAPGEF6,LRRC14,RB1,RINL,KIF13B,BANF1,ZNF746,CTR9,YBX1,BCL2,MAML1,SLC12A2,HDHD2,PREB,ATP5IF1,CYTH1,TRAPPC9,ERLIN1,ACSL3,LDB1,RTF1,UBE4B,SYVN1,APPL1,DAPK3,ISG15,MASTL,GOLGA4,CDC27,LAMTOR4,EXOC4,SIAH2,YWHAZ,RUVBL2,RBBP4,TOB1,N4BP2L2,RNF114,USP7,CYLD,MPHOSPH8,FOXM1,SUMO2,TOR1AIP1,SMARCA4,RRAGC,TWF2,RAD23A,RPL11,VAV1,RRN3,MDM2,CCDC50,IARS,KIF14,PIN1,PPME1,AKAP8,PDCD2,DVL2,CHP1,ARHGAP17,TIMP2,NXT1,PPP1R18,NFATC2,TOR1AIP2,BICD2,VDAC1,TOLLIP,BTBD1,SRSF1,AFDN,DNAJC10,ATP1A1,PLEKHG4B,STK38,TULP3,STAT6,NCOA1,MAPK1,TSPAN5,ABCA1,CBX4,ZC3HC1,PARD3,MIF,GCLM,KIF3B,SMAP1,MCM10,SH2D3A,SHPRH,DCTN2,AGO2,DBF4,SMC6,ARFIP2,PAWR,MYO9B,DCUN1D4,GGA2,FZD6,FBXO5,PTPN2,FGFR3,CTNNBL1,TANK,NABP2,ARHGEF2,H2AFY,ATG13,ABCD1,PTGES3,FBL,STAT3,CAMK2G,MYO5A,RNF5,TGFB1,PPP1R9B,TELO2,MLEC,RHOA,PRKDC,MIER1,PRKAR1B,RFFL,RANGAP1,ARHGEF12,BORA,HSPA1B,MFN2,MAPK3,CNOT9,MTMR3,BIRC5,ELMO1,PKD2,SRSF3,UBE2C,PGAM1,SLF2,RAB3IL1 |
| 3.415e-16 | -35.61 | nuclear transport | biological process | GO:0051169 | 263 | 93 | 17256 | 2622 |
POLA2,NDC1,NUP188,SARNP,TSC2,THOC1,RBM8A,ALKBH5,AGFG1,SNRPD3,RPAIN,FBXO22,HNRNPA2B1,CDK5,ANKLE1,NUP210,SNUPN,EIF4A3,SRSF4,NUP107,TNPO2,NUP153,CHTOP,AHCYL1,ZC3H3,SEH1L,CHP1,FYTTD1,SEC61B,NXT1,SNRPB,POLR2D,RNPS1,SLBP,ATXN1,DDX20,HTATIP2,NUP155,NUTF2,LSG1,RPSA,SRSF1,GEMIN5,HHEX,ARNTL,ANP32E,KPNA2,SNRPG,RRS1,SMURF1,NMD3,AAAS,GEMIN7,TMEM33,NXT2,RPS15,CDC40,PHB2,SRSF6,RAE1,NUP54,XPO7,NUP205,BANF1,TNPO3,ANP32A,GEMIN6,UPF2,GLE1,GEMIN4,CPSF4,STAT3,NUP85,RBM15B,SRSF11,EIF5A,TGFB1,PPP3CA,SRSF5,PTTG1IP,DDX39A,SYMPK,RAB18,TSC1,KPNA4,KPNA1,UPF1,PML,PPP3R1,NUP62,SRSF3,NUP58,IPO4 |
| 3.560e-16 | -35.57 | nucleocytoplasmic transport | biological process | GO:0006913 | 259 | 92 | 17256 | 2622 |
POLA2,NDC1,NUP188,SARNP,TSC2,THOC1,RBM8A,ALKBH5,AGFG1,SNRPD3,RPAIN,FBXO22,HNRNPA2B1,CDK5,ANKLE1,NUP210,SNUPN,EIF4A3,SRSF4,NUP107,TNPO2,NUP153,CHTOP,AHCYL1,ZC3H3,SEH1L,CHP1,FYTTD1,SEC61B,NXT1,SNRPB,POLR2D,RNPS1,SLBP,ATXN1,DDX20,HTATIP2,NUP155,NUTF2,LSG1,RPSA,SRSF1,GEMIN5,HHEX,ARNTL,ANP32E,KPNA2,SNRPG,RRS1,SMURF1,NMD3,AAAS,GEMIN7,TMEM33,NXT2,RPS15,CDC40,PHB2,SRSF6,RAE1,NUP54,XPO7,NUP205,TNPO3,ANP32A,GEMIN6,UPF2,GLE1,GEMIN4,CPSF4,STAT3,NUP85,RBM15B,SRSF11,EIF5A,TGFB1,PPP3CA,SRSF5,PTTG1IP,DDX39A,SYMPK,RAB18,TSC1,KPNA4,KPNA1,UPF1,PML,PPP3R1,NUP62,SRSF3,NUP58,IPO4 |
| 3.920e-16 | -35.48 | viral process | biological process | GO:0016032 | 652 | 178 | 17256 | 2622 |
NUP188,PDCD6IP,TSC2,UBN1,KDM4A,TAP1,CUL1,SND1,UBE2I,BECN1,SF3B2,RPL23A,USF1,NUP210,CDC42,IL6ST,ZNF639,SIVA1,AP1M1,AP2B1,NUP153,SEH1L,PCBP2,CARM1,RBX1,SLC25A5,EIF3A,RPL37,RPS27A,RPS14,EIF2D,ITGB1,ATP6V0C,KPNA2,VPS4A,COPS6,RPS26,RTN3,AAAS,DDX58,RPS15,DHX9,RPL15,KLC1,CDK13,EIF2AK4,RAB6A,NCKAP1,ITGB5,NUP205,WDR48,MCTS1,CFLAR,TMEM250,RB1,BANF1,MDFIC,CPSF4,LRSAM1,NUP85,MORC3,EIF3L,ZMYND11,RPL6,RPS10,RPS24,EIF4H,PSMB3,NMT2,ISG15,XRCC5,RPL36,DERL1,SCARB2,KPNA1,SYNCRIP,CCDC86,NUP62,MAP3K5,NUP58,USP7,WASF2,NDC1,CHMP2A,KARS,RPLP2,IVNS1ABP,DYNLL1,EIF3D,RAC1,MON1B,BCL2L1,IRF3,AP1B1,LYN,PCBP1,RPL11,RAD23A,CCNA2,MDM2,SP100,SHC1,NUP107,TAP2,MAVS,RBM15,ABI1,PDCL3,RPL29,BRD4,RPL35,RAB7A,SELPLG,PSMB7,RPL38,HTATIP2,NUP155,VDAC1,AZI2,CHMP2B,RAB1A,PSMB9,EIF3G,RPS9,CENPU,RPSA,IDE,CHMP4A,RBL1,HIPK2,STAT1,RPLP1,H2AFX,AP1S1,CHMP4B,SCARB1,MAPK1,XRCC4,AP2S1,RPS2,RAE1,NUP54,ARF1,XPR1,TFRC,HLA-A,WWP2,CCNK,GRK2,RPL17,TANK,RPL19,CREB1,STAT3,MSH6,PACS2,RBM15B,TGFB1,RHOA,KAT2A,RPL8,RCOR1,PACS1,RPL27A,FADD,HSPA1B,MAPK3,HLA-B,KPNA4,RPL32,ELMO1,ZC3H7B,PML,CD81,USF2,CHMP7,DDB1,SNAPIN |
| 4.198e-16 | -35.41 | protein modification by small protein conjugation | biological process | GO:0032446 | 786 | 205 | 17256 | 2622 |
MIB2,NUP188,UBE2E2,DCAF15,TRIM11,XIAP,CUL1,UBE2Z,UBE2Q1,NHLRC3,UBE2I,BIRC2,RNF103,FBXO22,ZER1,FANCL,PCNA,PSMD1,NUP210,CDC42,ATG3,FBXW2,NUP153,MARCH2,RNF26,ASB6,SENP1,SEH1L,RYBP,PLK1,SP3,TRIM8,RBX1,VHL,TOPORS,UBE2V1,USP22,AURKB,DCUN1D5,BRCA1,CCNF,CBFB,TRIM4,PAF1,RAD18,RPS27A,PSMD8,TPP2,SOCS4,ARRDC1,KLHL42,FBXL3,ARRB2,PSMC1,ZNF598,DCAF5,AAAS,UBE2D3,WSB2,RMND5A,UFC1,TOP2B,ZNRF3,PSMD9,CDC73,NUP205,DDRGK1,DTL,RNF121,UBE2Q2,MED8,KLHL5,MED10,RNFT1,ZNRF2,HDAC7,FBXO7,PPIL2,CTR9,BCL2,FBXL7,RNF135,UBE3C,LRSAM1,NUP85,SOCS5,UBE2QL1,DCAF8,PSMA1,RTF1,UBE4B,SYVN1,NFATC2IP,PSMB3,ISG15,PSMC4,CAND1,DERL1,CDC27,KLHL15,SIAH2,DCAF11,PIAS2,VCPIP1,NUP62,RNF14,RNF139,NUP58,RNF114,USP7,NDC1,TRIM41,TRAF7,MPHOSPH8,SUZ12,UBR2,SUMO2,WDTC1,KLHL18,ANKIB1,USP5,PSMA6,MDM2,FBXL6,SIAH1,MTA1,UBA5,NUP107,SOCS6,ANAPC7,TTC3,RNF19A,SPSB3,RNF169,RLIM,PRPF19,BIRC3,PSMA8,RNF25,PCGF6,PSMB7,CUL3,KIAA1586,NUP155,ASB13,CDC23,PSMB9,TRIM28,BTBD1,SOCS7,PEX5,CDC16,NSMCE2,PSMD3,UHRF2,RNF38,TRIM32,SMURF1,CBX4,ZC3HC1,TRIP12,KLHL21,SHPRH,RAE1,ZFP91,EYA1,NUP54,CDCA3,CDCA8,CBLL1,BRAP,UBE4A,DCUN1D4,WWP2,RFWD3,FBXO3,HERC3,PSMD2,KLHL20,HUWE1,FEM1B,LTN1,UBE3B,FBXL19,UBE2M,RNF5,DCAF6,LONRF3,TNFAIP3,PRKDC,RFFL,FBXO9,ANAPC2,RANGAP1,PCGF1,FBXO21,KEAP1,FBXO41,BIRC5,DTX4,KBTBD7,PPP1R11,UBE2C,ANAPC4,DDB1 |
| 4.873e-16 | -35.26 | MOHANKUMAR_TLX1_TARGETS_UP | MSigDB lists | MOHANKUMAR_TLX1_TARGETS_UP | 383 | 120 | 17377 | 2626 |
POLA2,ZNF207,UBL3,SNX27,NOP2,UGP2,ALKBH5,MOGS,OAT,SLC20A1,CMTM6,USP5,BCAT2,PCNA,NUP210,METTL14,SLC44A1,PHTF1,CS,HADHB,PARL,TTC3,RPN2,EIF5,LRRC59,CLN6,DNMT1,ZNF583,CARM1,DCTN1,PLK1,COPS8,CLPTM1,PPT1,IDH3A,RRM2,HTATIP2,CDC6,NUTF2,ICMT,ASB13,SHCBP1,MAT2A,ASF1B,SRSF1,RAD51C,RBM47,CERS6,TIMM17A,E2F4,CORO1C,IARS2,H2AFX,KPNA2,ANP32E,PIEZO1,CLU,VPS4A,LRP8,TSPAN5,CAPN1,DYNC1LI2,TUBB,WSB2,SEPHS2,UBE2D3,PKP4,RAE1,RRM1,MED13L,DNAJB1,RAB6A,SLC35B1,PIP4K2A,WRB,BZW2,COPB2,SPAG5,CHKA,TFAP4,RB1,HOMER1,FUT8,NAA50,MSH2,BCL2,PHKG2,HNRNPM,TMED2,LDHB,PPAN,ELOVL5,PRRC2A,PRKDC,AMD1,MEMO1,LDHA,ILF3,TBRG4,SEPT7,TOMM40,EIF4H,EIF4G2,CCT8,PICALM,RHOB,HSPA1B,RPA1,CAT,GNAS,PRDX3,TATDN2,SIAH2,GLG1,PGRMC1,CENPT,ZMIZ1,CDK2,CCNB2,RNF139 |
| 5.000e-16 | -35.23 | MODULE_54 | MSigDB lists | MODULE_54 | 249 | 89 | 17377 | 2626 |
TMEM106C,H2AFZ,NQO1,FOXM1,PTTG1,TPX2,NUF2,KIF2C,ZNF267,ORC1,CCNB1,KIFC1,CDKN2C,PCNA,CCNA2,IARS,IMPAD1,UCHL5,KIF14,CDC25B,TACC3,PLK1,RFC3,PSRC1,PBK,SNRPB,MKI67,RRM2,NUSAP1,CDC6,AURKB,SMC2,PKMYT1,CCNF,ANLN,MCM2,SHCBP1,SLC25A5,ODC1,ASF1B,CHAF1A,PRIM1,CEP55,NRM,H2AFX,ANP32E,KPNA2,BEND3,LRP8,ZC3HC1,PFKP,POLQ,HSPH1,KIAA0100,HJURP,DEPDC1,CENPF,RRM1,KIF23,BLM,WDR5,SPAG5,FKBP1A,HUWE1,MCM5,ARL6IP1,MSH2,TIMELESS,AHCY,KNTC1,IMPA2,SMC4,GINS1,ASPM,MYBL2,ADSL,KIF11,PRDX1,MTHFD2,ATAD2,BIRC5,NEIL3,CDCA5,FAM83D,E2F1,HMGB2,CCNB2,UBE2C,BYSL |
| 5.099e-16 | -35.21 | BOYAULT_LIVER_CANCER_SUBCLASS_G3_UP | MSigDB lists | BOYAULT_LIVER_CANCER_SUBCLASS_G3_UP | 181 | 72 | 17377 | 2626 |
SRM,TXN,CKLF,WDYHV1,UCK2,EBNA1BP2,KIF2C,STMN1,FANCI,PAPOLA,CSDE1,CCNA2,NOL11,EIF4A3,UTP18,NUP107,SRI,PDCD2,LRRC59,TACC3,CCT2,NRAS,RFC3,RAD51AP1,GMFB,NUP155,CDC6,EML4,DHX15,EIF3H,PLEKHF2,PRIM1,TAF2,KIF2A,DNAJC10,SMAD2,HNRNPR,CEP55,MPV17,CANT1,ANP32E,COIL,CSNK1D,MAPRE1,MRPL42,HJURP,SEC61G,POLR2K,KLC1,LANCL1,NCAPG,SUB1,ATIC,BRD7,CENPM,PTGES3,LPCAT1,TMX1,RPRD1A,RPL8,ADSL,RIT1,FXR1,KDM3A,CBX3,PSMC4,TPD52L2,HGS,CCDC86,NSF,DUSP3,RBBP4 |
| 5.185e-16 | -35.20 | mRNA Splicing - Major Pathway | REACTOME pathways | R-HSA-72163 | 187 | 77 | 10287 | 1696 |
SART1,CHERP,XAB2,SF3B1,RBM8A,USP39,SNRPD3,PCBP1,PAPOLA,SF3B2,HNRNPA2B1,EIF4A3,SRSF4,TRA2B,AQR,CCAR1,PCBP2,SRSF10,CSTF1,PRPF19,CDC5L,SNRNP200,POLR2G,POLR2L,SNRPB,PPIE,CRNKL1,HNRNPF,POLR2D,RNPS1,LSM8,PRPF3,TXNL4A,DHX15,SRSF1,SUGP1,HNRNPR,LSM6,DHX16,U2SURP,PQBP1,PRPF4,FUS,SNRPG,SMNDC1,DDX42,CWC25,CDC40,POLR2K,SRSF6,DHX9,SRRT,GTF2F1,RBM17,DNAJC8,CTNNBL1,CWC27,EFTUD2,BUD31,YBX1,CPSF4,HNRNPM,SRSF11,POLR2I,SF3B6,PPWD1,SRSF5,SYMPK,SF3A2,SNRPA,POLR2A,DDX23,POLR2J,RBMX,DDX5,SRSF3,SNRNP70 |
| 5.190e-16 | -35.19 | MORF_AP3D1 | MSigDB lists | MORF_AP3D1 | 122 | 56 | 17377 | 2626 |
COX5B,KARS,NCOR2,IMMT,DYNLL1,SUMO2,ACTR3,DCTN2,STARD7,CUL1,SND1,XPO7,AP3S1,SDHA,NDUFS4,RAD23A,HNRNPA2B1,FKBP1A,PSMD1,DNAJC8,EIF2S2,ARPC5,PIN1,CAPZA1,HADHB,CS,TARDBP,TCEA1,AHCYL1,PDIA6,IFRD1,SNRNP200,POLR2I,POLR2L,WDR1,VDAC2,PSMB7,SEPT7,MCFD2,TXNL4A,EIF4H,MAP2K2,SNRPA,RHEB,XRCC5,PPP2CA,FNTA,ACLY,RBMS1,IMPDH1,UQCRH,MDH1,RUVBL2,IDH3B,PGAM1,ZNF146 |
| 5.335e-16 | -35.17 | GO_NUCLEAR_SPECK | MSigDB lists | GO_NUCLEAR_SPECK | 185 | 73 | 17377 | 2626 |
MBD1,SARNP,PNISR,THOC1,SF3B1,CXXC1,RBM8A,ALKBH5,CCNL2,PRKACA,RBM4,NEK6,EIF4A3,NSRP1,GLIS2,PIN1,SRSF4,TARDBP,FAM76B,CHTOP,RBM15,OGG1,CDK12,TIMM50,SRSF10,CDC5L,PRPF19,FYTTD1,NXT1,RNPS1,CRNKL1,TOPORS,PRPF3,EAF2,SRSF1,EIF4ENIF1,CLK3,LUC7L3,PQBP1,ATXN2L,PRPF4,CBX4,SMNDC1,DDX42,SRSF6,CBLL1,SMC6,CDK13,THRAP3,CSNK1A1,METTL3,PRPF18,LMNA,PPIG,PPP1R8,EFTUD2,CTR9,MAML1,LUC7L2,YTHDC1,PSPC1,BCLAF1,SRSF5,PATL1,SF3A2,RBM25,PIAS2,DUSP11,SRSF3,SNRNP70,ZNF830,ZMIZ1,IFI16 |
| 5.541e-16 | -35.13 | GSE21927_BALBC_VS_C57BL6_MONOCYTE_TUMOR_UP | MSigDB lists | GSE21927_BALBC_VS_C57BL6_MONOCYTE_TUMOR_UP | 189 | 74 | 17377 | 2626 |
LYRM4,RAC1,OLA1,CSNK2A1,NIT2,SLC25A44,RAD23A,KIFC1,NAPG,NOL11,GOT2,DNAAF2,PPP6C,MRPS27,INTS12,TARDBP,ECD,MCMBP,PRPF19,PGAP2,METTL1,DRAP1,CPOX,RNPS1,PSMG1,ELP4,UTP3,CDC23,RFC2,EIF3A,PRIM1,ALG3,PSMD3,PPM1G,C1orf109,UQCRH,NCLN,ATF6,MIF,UBE2D3,MAPRE1,MRPS2,TMEM165,EBP,DDRGK1,RFWD3,FASTKD3,MED8,MRPL40,CYC1,MRPL11,ERI3,SMC4,RBM15B,PPAN,MOB4,TIMM8B,TRAFD1,MAPKAPK3,USP10,MRPL16,LY6E,ABCF1,ISG15,SLC19A1,KIF18A,PLAA,STX18,NFIL3,COX8A,PML,ACAT1,GPI,EHD4 |
| 5.784e-16 | -35.09 | FOURNIER_ACINAR_DEVELOPMENT_LATE_2 | MSigDB lists | FOURNIER_ACINAR_DEVELOPMENT_LATE_2 | 262 | 92 | 17377 | 2626 |
NUP188,H2AFZ,TXN,FOXM1,DCAF15,PTTG1,UCK2,MYH9,CSNK2A1,SMARCA4,KIF2C,AGFG1,CUTC,FANCI,PHC2,UCHL5,DUT,SRSF4,POP7,NUP107,NOC2L,NUP153,RNASEH2A,AQR,PDIA6,SRSF10,PLK1,CCT2,RFC3,SNRPB,MAP4K4,RRM2,DNAJC9,NUSAP1,CDC6,MCM2,CCNF,H2AFV,ODC1,MAK16,DHX15,ARF4,CHAF1A,SUPT16H,DNAJC10,PRPF4,XRCC3,ANP32E,ACTB,DVL1,PITRM1,POLQ,DEPDC1,HJURP,DBF4,CDCA3,RACGAP1,BLM,ITGB5,METTL3,NUP205,RFWD3,DTL,PRC1,TIMELESS,GEMIN6,ANXA5,PTGES3,TTLL12,NUP85,MSH6,SMC4,PREB,GINS1,SRSF11,NASP,ASPM,PRKDC,LDHA,ILF3,PRDX1,UAP1,RBM25,BIRC5,PRDX3,FAM3C,IMPDH1,PLOD3,CDK2,YWHAH,MRPL3,GCSH |
| 5.808e-16 | -35.08 | ncRNA metabolic process | biological process | GO:0034660 | 577 | 162 | 17256 | 2622 |
DDX47,NOP2,EBNA1BP2,SNAPC4,RPL23A,KRR1,UTP25,PA2G4,NOL11,THADA,EIF4A3,INTS1,TRMU,POP7,RPF2,MYBL1,FTSJ3,METTL1,RPP25,LARS,EXOSC6,HARS,NOL8,NSUN2,UTP3,PRKRA,MAK16,RPL37,SMAD2,RPS27A,RPS14,WDR4,IARS2,QRSL1,RNASEL,RRS1,OSGEPL1,SMAD1,RPS26,SEPHS2,CTU2,RPS15,POLR2K,RPL15,PARN,METTL3,SRRT,LYAR,DDX56,EXOSC7,INTS7,RTCB,ICE2,GEMIN4,CPSF4,MRM3,PPA1,NSUN4,CARS2,POLR2I,ELL2,TEX10,TYW1,RPL6,GTPBP4,RPS10,UTP15,RPS24,EXOSC9,RPL36,EPRS,POLR2J,QARS,TYW5,TRMT10B,DTD1,TSEN15,KARS,SART1,TP53RK,RPLP2,MRPL39,LAGE3,C2orf49,RPL11,HNRNPA2B1,FARSA,IARS,DUS4L,CD3EAP,UTP18,GRSF1,EXOSC1,NABP1,INTS12,UTP4,RPRD1B,MRM2,RPL29,RPL35,POLR2G,POLR2L,INTS13,METTL2A,POLR2D,RPL38,ELP4,POLG2,GAR1,RPS9,RPSA,DDX17,NSA2,DUS3L,LSM6,DGCR8,TBL3,FTSJ1,RPLP1,PPA2,PDCD11,CSNK1D,INTS2,NIFK,RPS2,RRP15,TRMT6,AGO2,GTF3A,TUT4,PNO1,RRP36,GTF2F1,KRI1,CCNK,GTPBP3,GATC,RPL17,ELP5,PELO,DUS2,NABP2,RPL19,POLR1B,FBL,GTF3C6,RPRD1A,TRIR,WDR18,RPL8,BMS1,RPL27A,TSR2,POLR2A,TARS,UTP20,RPL32,KHSRP,TAF6,BYSL,DDX52,TYW1B |
| 6.156e-16 | -35.02 | cellular component assembly | biological process | GO:0022607 | 2437 | 507 | 17256 | 2622 |
RAB14,FGFR1OP,MAX,PDCD6IP,ADD1,NDUFB6,ZDHHC8,XIAP,CUL1,USP39,CNTROB,CCNB1,OAT,MIS12,RPL23A,KIFC1,CDK5,NAPG,SNUPN,NEK6,DNAAF2,RAD23B,DNM2,TRA2B,AP2B1,NUP153,TFG,SRSF10,ERCC1,USO1,RHOBTB3,ATG9A,DDX20,AURKB,MCFD2,MCM2,FOXRED1,CLNS1A,EIF3A,STOML2,AHNAK,WAS,MID1IP1,SMAD2,BRD2,TMED10,RPS27A,PSMD8,RPS14,LUC7L3,AXIN1,EIF2D,ITGB1,PTPDC1,RRS1,SMAD1,RTN3,SLC25A33,NDUFV2,MAPRE1,DHPS,RHOC,VAV2,PRKAA1,DHX9,RRM1,RAB23,DNAAF5,KCTD17,KIF23,B4GALT1,HAUS4,PRPF39,ITGB5,PSMD9,PSEN1,VPS25,HAUS2,CDC73,NDUFS7,MCTS1,ATG4A,CFLAR,RTKN,NDUFS4,NDUFAF6,CD59,TFAP4,TMEM250,FKBP1A,PDXP,HDAC7,ATP6V0A2,FBXL7,GEMIN4,PIKFYVE,TNRC18,NUP85,PPP6R1,NSUN4,LUC7L2,TMED2,CYFIP1,DDX28,SIGMAR1,TSPYL4,RB1CC1,WDR1,RPS10,MYBL2,SEPT8,PLEC,CAPZA2,SRSF5,ADRB2,PKM,CYFIP2,EIF4H,PATL1,SF3A2,CCT8,RHOB,FAS,DERL1,SEC31A,CAT,EPRS,GOLGA2,NSF,RBMX,VCPIP1,CABIN1,WIPI2,NDE1,PPP6R3,CFAP20,CDK2,NUP58,CDKN2A,ZNF207,RHOG,NDC1,REPS2,RAF1,SF3B1,POC1A,EIF3D,CHD1L,RAC1,ANK3,ACTR3,C5orf30,TPX2,POMP,EFL1,PRKACA,GLRX3,STAM,APP,DECR1,CLUAP1,AHCTF1,SH3BP1,NUP107,NSFL1C,SEPT11,CEP63,DCTN1,GPX4,CCT2,ULK3,CDC123,GOPC,MAP4K4,CRNKL1,RPL38,POLR2D,CUL3,CIRBP,ATP6V0A1,GORAB,NDUFA7,RAB1A,TAZ,TRIM28,MAT2A,CENPU,TAF2,KIF2A,RAD51C,CHMP4A,HSPA4,GOLGA8A,H2AFX,SNRPG,BEND3,PPP5C,CSNK1D,ATMIN,TUBB,DYNC1LI2,POLQ,MZT1,NDUFS1,PKP4,ANXA6,SRSF6,MECP2,TWNK,FLOT1,ATG2B,WDR5,BLM,IFT27,RAB11A,PIP5K1C,RPA2,PDCD10,NDUFA2,NDUFB4,PTEN,CENPJ,AXIN2,GEMIN6,NAP1L4,NDUFA3,GTF2H2,IFT46,PACS2,PDPK1,TK1,TNFAIP3,TCTEX1D2,TMEM126B,NEK7,WDR18,EMP3,ADSL,RAB3IP,KIF11,PICALM,FADD,SH3GLB1,RPA1,HGS,PML,NAXE,CCDC69,SSNA1,HMGB2,NDUFS5,WDR62,TAF6,WDR45B,IPO4,DDB1,COX15,NPHP4,NOP2,ST13,UBN1,UQCR10,MCCC1,TAF6L,AGFG1,SNRPD3,S1PR2,BRIX1,MAP1LC3B,BECN1,SEC16A,BIRC2,CUTC,ATPAF1,EDC3,PRNP,DLG5,RAB8A,RAP1A,CDC42,RAB35,ZNHIT6,ATG3,XRCC2,NOC2L,ZFYVE27,RPF2,KHDC4,NDUFB9,NFU1,EIF5,CARMIL1,SRPK2,PTPRK,PLK1,COPS8,SNRNP200,SEPT9,RBX1,NCK1,BAZ2A,SNRPB,FOPNL,TMEM216,PSMG1,EZR,LNX2,ANLN,LUC7L,ASF1B,CHAF1A,DPYSL3,EPB41,TRIM4,PAF1,GEMIN5,UBTF,SEPT1,HSPB11,NIP7,E2F4,ATXN2L,MIA2,CAB39,ACTB,STK11,CHEK2,CLU,VPS4A,ROCK1,DVL1,SASS6,POT1,NAA60,GEMIN7,RPS15,HJURP,GORASP1,TM9SF4,CENPF,CTCF,MEF2A,RACGAP1,NCKAP1,ARID1B,RAPGEF6,PRPF18,NUP205,VASP,CCP110,VMP1,MBD2,SSBP3,XPA,ARL6IP1,CAPZA1,KIFAP3,BCL2,KNTC1,ATP6V0D1,PREB,HP1BP3,ATP5IF1,TRAPPC9,ACSL3,LDB1,RPL6,EIF2A,SEPT7,BBS12,CAND1,HAUS8,TSC1,NAP1L1,PCM1,SNAP23,ODF2,TBPL1,PRMT7,NUP62,YWHAZ,RUVBL2,EHD4,RBBP4,MYO9A,ECPAS,UNC13C,PDSS2,BCCIP,WASF2,KCTD7,SART1,CHMP2A,NDUFA5,PRKAB1,CORO7,TOMM20,CYLD,FAM92A,NDUFAF2,DYNLL1,XAB2,SLC2A1,SMARCA4,PLAGL2,RPL11,OIP5,ANKRD28,FARSA,RRN3,UBXN2A,MDM2,SAR1A,ABRAXAS2,PIN1,PPP6C,CORO1A,LMAN1,CLTB,STRAP,HTRA2,DVL2,CHP1,PRPF19,BIRC3,RAB7A,DMAC2,TUBGCP5,WIPF1,PRPF3,NDUFB1,CHMP2B,TXNL4A,PEF1,RPSA,SRSF1,IDE,UBXN2B,NDUFA11,ANP32E,XRCC3,CHMP4B,H3F3A,SMURF1,AP2S1,ABCA1,SMAD4,PARD3,RAD51D,TMEM33,MIF,KIF3B,NIFK,SHPRH,CDT1,AGO2,DCTN2,NUP54,ARFIP2,TIMM21,PAWR,CSNK1A1,TUBGCP2,FERMT3,FBXO5,FASTKD3,STARD9,NDUFV1,SEC24C,H2AFY,ANP32A,ATG13,NDUFS8,CENPM,PTGES3,ORC3,TTC17,MRPL11,CAMK2G,YTHDC1,TGFB1,PPAN,COA3,PPP1R9B,RHOA,NASP,SNX2,TIMMDC1,ASPM,MEN1,MAPK3,MFN2,DDX23,SEC23IP,ATP6V1D,NEK1,PDCD6,BIRC5,SNAP29,ACAT1,PKD2,CENPT,TAF12,PLOD3,UBE2C,CHMP7,TERF1 |
| 6.481e-16 | -34.97 | mRNA Splicing | REACTOME pathways | R-HSA-72172 | 195 | 79 | 10287 | 1696 |
SART1,CHERP,XAB2,SF3B1,RBM8A,USP39,SNRPD3,PCBP1,PAPOLA,SF3B2,HNRNPA2B1,EIF4A3,SRSF4,TRA2B,AQR,CCAR1,PCBP2,SRSF10,CSTF1,PRPF19,CDC5L,SNRNP200,POLR2G,POLR2L,SNRPB,PPIE,CRNKL1,HNRNPF,POLR2D,RNPS1,LSM8,PRPF3,TXNL4A,DHX15,SRSF1,SUGP1,HNRNPR,LSM6,DHX16,U2SURP,PQBP1,PRPF4,FUS,SNRPG,SMNDC1,DDX42,CWC25,CDC40,POLR2K,SRSF6,DHX9,PDCD7,SRRT,GTF2F1,RBM17,SNRNP25,DNAJC8,CTNNBL1,CWC27,EFTUD2,BUD31,YBX1,CPSF4,HNRNPM,SRSF11,POLR2I,SF3B6,PPWD1,SRSF5,SYMPK,SF3A2,SNRPA,POLR2A,DDX23,POLR2J,RBMX,DDX5,SRSF3,SNRNP70 |
| 6.679e-16 | -34.94 | GCCATNTTG_V$YY1_Q6 | MSigDB lists | GCCATNTTG_V$YY1_Q6 | 398 | 123 | 17377 | 2626 |
ZNF207,PRKCSH,WDR13,PPP1R15B,SUMO2,AGPAT1,ENSA,RUFY1,GIT2,CRKL,TMEM69,USF1,KDM2A,TBC1D14,AKAP8,CNPY4,PDS5B,CDKN1B,TRA2B,ZBTB22,TARDBP,RNF26,CHTOP,EIF5,RPRD1B,SCYL3,FTSJ3,ARID4A,RLIM,CPNE1,TRIM8,MIOS,KAT7,SLC26A6,KIF15,EZR,RAB1A,NDUFB1,GFER,RAB22A,MAT2A,SRSF1,DDX17,IWS1,MAP3K4,PPP2CA,DAP3,TMED10,SAFB,LUC7L3,RBMS1,ATE1,UQCRH,ATP6V0C,BTF3,ZBTB11,ZC3HC1,PRPF38B,NDUFS1,PHB2,NACA,ADO,STRN4,RRM1,TIA1,CTCF,MYNN,RACGAP1,JMJD6,ARF1,PMF1,CSNK1A1,ASXL2,METTL3,CNOT3,CCNK,RPN1,ZNF335,FOXN2,YBX1,NDUFS8,RBM3,KNTC1,PCYT2,TTC17,MRPL11,GNAI2,RNF5,LYPLA2,RPRD1A,NASP,C16orf72,PSPC1,PPP1R21,TOP3A,ILF3,MAP4K3,SRSF5,ARMC8,EIF4G2,KDM3A,NCDN,POLR2A,RXRB,MTMR3,UTP20,TSC1,MAGT1,NSF,CCDC6,RBMX,SETD3,HNRNPH3,PITX1,COX8A,SRSF3,WIPI2,RUFY3,TAF6,PDSS2,ANAPC4,N4BP2L2,NUDT3 |
| 7.151e-16 | -34.87 | regulation of nucleobase-containing compound metabolic process | biological process | GO:0019219 | 4306 | 821 | 17256 | 2622 |
ZBTB10,KDM4A,HEXB,XIAP,CCNL2,EDRF1,RBM4,ZNF275,PABPC4,CDK5,CALM2,USF1,PSMD1,CIPC,NSRP1,THAP4,SRSF4,DNM2,CRY2,NUP153,FNIP2,ECD,SENP1,BAK1,PLK3,ZNF672,ERCC1,ZNF559,AATF,GABPA,EHMT1,HNRNPF,WDHD1,MIER2,TOPORS,ARF4,STOML2,BRMS1,BOLA3,AHNAK,SMAD2,RPS27A,ZNF689,AXIN1,PRDX5,OGT,VIPAS39,RNASEL,TRIM52,TFDP2,SMAD1,E2F2,ZNF75A,AAAS,PDCD4,SLC25A33,ZNF720,SSRP1,HIVEP3,DHX9,EZH1,EIF2AK4,PSMD9,PARN,CDC73,MCTS1,DDRGK1,TFAP4,SMC3,MEGF8,PHF14,ZNF326,FOXN2,MYDGF,CPSF4,PABPC1,NUP85,IFRD1,AGGF1,RBM42,ETV3,FOXK1,RB1CC1,ZMYND11,MTA2,GTPBP4,MYBL2,BCLAF1,SRSF5,CBFA2T2,ELK1,KPNA1,PDLIM1,ETS2,SETD3,CNOT6,ZNF830,SGF29,NUP58,EGLN1,ZNF207,RHOG,ZNF296,KARS,SARNP,TRERF1,IVNS1ABP,UBR2,PTTG1,WDTC1,CREBL2,ZNF267,INO80E,SAFB2,RCOR3,TCF19,APP,AHCTF1,ZNF420,SP100,ZKSCAN1,MTA1,GMEB1,NUP107,ZNF226,MAVS,ATF2,RBM15,ZC3H3,RPRD1B,CGGBP1,RNF169,CPNE1,PSRC1,POLR2L,EID1,KAT7,WBP2,RNPS1,CIRBP,E2F3,HTATIP2,PFKFB3,MEF2D,TAZ,DDX17,TAF2,PPP2CA,CHCHD3,HIPK2,TICAM1,FUS,ZBTB11,LRP8,USP13,COMMD10,ZNF786,ZNF445,SRSF6,ZFP91,HABP4,TRAK1,JMJD6,GMCL1,ABHD14B,WDR5,ETS1,NEXMIF,ZNF92,RPA2,ZBTB45,PSMD2,SUV39H2,PPP1R8,PRDM4,ZNF260,DCP1A,ZNF710,GTF2H2,MED22,PDPK1,PPP3CA,TNFAIP3,ZNF512,ZP3,PICALM,ZNF180,ZNF862,KEAP1,GPS2,PARG,PITX1,LRPPRC,PML,HMGB2,CD81,PARP10,IGBP1,USF2,YWHAH,THAP5,FAF1,AGRN,THOC1,AAMDC,GPBP1L1,TRIM11,RBM8A,CSNK2A1,SND1,BIRC2,PAPOLA,CREM,PRNP,LIN9,TET3,PCNA,NUP210,GLIS2,ZNF639,ETV6,PIK3R2,NOC2L,MYBL1,MTPN,CCAR1,RYBP,PTPRK,PLK1,SP3,EXOSC6,CELSR2,RBX1,PBXIP1,BAZ2A,RAD51AP1,ZBED5,MRPL12,EZR,CDC6,UBE2V1,LRP5,PBRM1,EAF2,BRCA1,USP21,TONSL,CHD3,ZNF367,E2F4,KPNA2,DVL1,ZNF45,BEND6,FAM208A,POT1,ZNF564,FUBP1,LZTR1,PHB2,CENPF,CTCF,CHCHD2,CDK13,DNAJB1,PPP3CB,RLF,ASXL2,CNOT11,CRLF3,ARID1B,LRRC14,SUB1,RB1,MLX,MED8,TIGAR,MBD2,SSBP3,ZNF746,CTR9,TIMELESS,MDFIC,AFF1,ICE2,MAML1,PREB,TRAPPC9,LDB1,UTP15,KRAS,RTF1,ZNF761,NFATC2IP,RBM38,IRF5,ZNF174,PSMC4,RXRB,SYNCRIP,NLRC5,TBPL1,PRMT7,RUVBL2,USP7,CYLD,TRAF7,ARID2,FOXM1,DYNLL1,ZNF416,DUSP22,PCBP1,COMMD8,ZNF121,VAV1,CSDE1,ZBTB21,NRF1,PSMA6,ZNF473,MDM2,KMT5C,ZNF302,PIN1,TARDBP,AHCYL1,STRAP,SAP30L,SPIDR,ZNF583,DVL2,PRPF19,KDM3B,PPIF,TIMP2,POLR2G,ZNF780B,PSMA8,BTG2,PPIE,NUP155,NFATC2,KDM1B,USP36,SRSF1,ZNF700,SCAP,RBL1,CLK3,MAFK,FASTK,PSMD3,ZNF436,UHRF2,DNAJC17,NCOA1,H3F3A,SMAD4,ZNF146,BCL2L12,SLC30A9,CTDP1,MTERF1,DAP,CDT1,AGO2,ARID5A,GTF3A,HMGN3,NKRF,CDK11B,PAGR1,FZD6,TFRC,WRNIP1,PTPN2,IRF4,SS18L1,PTGES3,RBM15B,YTHDC1,RPRD1A,RHOA,HMGN5,BTAF1,PRKDC,ZNF202,ZMYM5,PCGF1,TRIM26,BIRC5,TWSG1,L3MBTL3,TFE3,CDCA7L,BBX,E2F1,PKD2,RBPJ,TAF12,NR2F2,PGAM1,HIPK3,IFI16,NUP188,TXN,ZNF496,MAX,H2AFZ,TSC22D3,CXXC1,YTHDF3,CCNB1,UBE2I,COMMD6,MYEF2,PARK7,GLMP,PA2G4,NOL11,PARPBP,FIZ1,ZNF200,TRA2B,TAF5L,SMARCE1,DNMT1,ZNF800,SEH1L,CDC5L,SRSF10,ZNF524,KLF10,ELOA,MRNIP,DDX20,SUPT20H,AURKB,USP22,CBFB,RFC2,ZMYM3,IWS1,DOT1L,MAP3K4,HHEX,BRD2,PSMD8,RPS14,BTF3,ARRB2,SLF1,TRAF5,CCDC59,NMD3,HDAC2,PTOV1,DDX58,HSPH1,EWSR1,POLR2K,CHTF18,PRKAA1,NOTCH2,PMF1,SUPT7L,ZNF79,PSEN1,ZNF518A,METTL3,VPS25,YY1AP1,CNOT3,JMY,CFLAR,LHX8,EXOSC7,KLF16,HDAC7,MSH2,GNAI2,TNRC18,EEF1D,TERF2,PHF10,ZNF84,ELL2,ZNF574,USF3,EXOSC9,ARID1A,ADRB2,C9orf40,FXR1,KDM3A,MAP2K2,CCT8,PSMB3,PHF6,XRCC5,CAT,PFDN5,ZNF777,SERTAD2,EPOP,ZFP92,RBMX,QARS,MED15,CEBPG,PPP3R1,PIAS2,YY1,MAP3K5,RNF14,CDK2,ZC3HAV1,CDKN2A,ZNF511,NDC1,DNMT3A,ATXN3,RWDD1,ZBTB37,RPS6KA1,RAF1,SUZ12,RAC1,MAGED1,TERF2IP,SPINDOC,CCNA2,ZNF75D,SHC1,KDM2A,UCHL5,LPIN2,CDKN1B,CDK12,SAP30,CCT2,BRD4,RFC3,ERF,DRAP1,CUL3,ELP4,EDF1,H2AFV,PSMB9,ERC1,TRIM28,CENPU,PRDM11,SUPT16H,VEZF1,ZNF282,HINT1,CERS6,SAFB,STAT1,H2AFX,ATF6,TRIM32,BEND3,EYA2,ATMIN,RHEBL1,POLQ,POU3F2,NCOR2,DEPDC1,MECP2,TCF3,BABAM1,ARGLU1,SECISBP2,MYNN,BLM,POFUT1,FOXO3,HMG20A,MAD2L2,WWP2,GTF2F1,RBM17,CCNK,PTEN,ELP5,AXIN2,CARF,CITED2,CREB1,CNOT6L,MSH6,NCOA2,TSHZ1,ZFP64,KAT2A,NEK7,WDR18,ILF3,PARP4,RFXANK,TBRG4,KLF6,COMMD4,FADD,POLR2A,CBX3,PRDX3,ZHX1,TFDP1,KHSRP,DDX5,BRWD3,TAF6,PURA,FAM83G,RORB,ZBED3,CCNC,ZNF76,IER2,NOP2,HNRNPAB,UBN1,NF1,KMT2E,PTP4A3,ZNF107,SIRT2,TAF6L,COMMD5,MAPK14,SNAPC4,ZNF696,CYREN,JAZF1,METTL14,PHTF1,SRI,ZBTB22,TCEA1,OGG1,ARID4A,CARM1,TRIM14,ELOF1,SRPK2,DEAF1,TRIM8,NCK1,VHL,RIOX2,SREK1,RRM2,SOX4,KMT2C,ASF1B,UBTF,PAF1,BRWD1,PQBP1,BAZ1B,ZNF268,CHEK2,CLU,RPS26,PSMC1,UBE2D3,PPP1R12A,ZNF768,NACA,CIB1,MED13L,TIA1,MEF2A,THRAP3,TTF1,SRRT,NUP205,LYAR,NFATC3,ZNF449,MED10,ZNF335,BUD31,YBX1,ACAD8,MCPH1,ZNF189,HP1BP3,VOPP1,ATP5IF1,CREG1,ERLIN1,CIC,RPL6,PSMA1,EIF2A,SLTM,DAPK3,CAND1,RBM25,KLHL15,NFIL3,SIAH2,NUP62,YWHAZ,ZFP90,RBBP4,SNRNP70,HNRNPDL,TOB1,N4BP2L2,ZBTB24,SMARCD1,ADNP2,TCF12,MBD1,ASH1L,MPHOSPH8,SMARCA4,PLAGL2,NSD3,IRF3,ORC1,CHD1,MEAF6,MXD1,PAIP1,HNRNPA2B1,SAP130,RRN3,BABAM2,NVL,EXOSC1,AKAP8,CHTOP,F2R,UTP4,ZNF770,RLIM,MOSPD1,CHP1,POU2AF1,FAM172A,ZNF500,RNF25,SMU1,PCGF6,PSMB7,ATXN1,BOLA1,GLO1,ERBIN,MBD3,ZNF317,TAB2,HNRNPR,TULP3,STAT6,ARNTL,AKNA,SMURF1,MAPK1,BRD9,CBX4,NAT14,DNAJC2,TRIP12,ZNF316,RAE1,EYA1,SCYL1,NUP54,DBF4,KLF13,PAWR,MXD4,FBXO5,FASTKD3,KMT5A,PELO,NABP2,H2AFY,ANP32A,BRD7,ARHGEF2,STAT3,TGFB1,SAMD4B,PHF20L1,DCAF6,HMGN1,PSPC1,HELB,MIER1,RCOR1,PRMT2,MEN1,ZNF407,CDK11A,SNRPA,MAPK3,TFEB,HSPA1B,CNOT9,LEMD2,UPF1,ATAD2,KMT2B,ZRANB2,SRSF3,CENPT,ZMIZ1,HRAS,TERF1,SLF2 |
| 7.172e-16 | -34.87 | SF3A2 (splicing factor 3a subunit 2) | protein interactions | 8175 | 150 | 66 | 17029 | 2761 |
ZNF207,SART1,HNRNPAB,CHERP,SF3B1,SNRPD3,PCBP1,PABPC4,SF3B2,HNRNPA2B1,SRSF4,TRA2B,AQR,CCAR1,PRPF19,CDC5L,SNRNP200,SNRPB,PPIE,CIRBP,RNPS1,CUL3,PRPF3,DHX15,SRSF1,DDX17,SUGP1,HNRNPR,PSMD3,U2SURP,PQBP1,PRPF4,FUS,SNRPG,NKAPD1,SMNDC1,DDX42,SRSF6,RAE1,DHX9,ARGLU1,SRRT,RBM17,DNAJC8,CTNNBL1,PPP1R8,EFTUD2,BUD31,RBM3,YBX1,AGGF1,TRIR,SF3B6,ILF3,SRSF5,ISG15,SNRPA,DDX23,SYNCRIP,RBMX,DDX5,SRSF3,ISY1-RAB43,CFAP20,ZNF830,SNRNP70 |
| 7.359e-16 | -34.85 | CDK1 (cyclin dependent kinase 1) | protein interactions | 983 | 299 | 105 | 17029 | 2761 |
COX15,TXN,REPS2,FOXM1,KMT2E,PTTG1,CSNK2A1,BCL2L1,CCNB1,UBE2I,STMN1,LYN,PCBP1,SDHA,CREM,EEF2K,DLG5,NRF1,APLP2,PCNA,CCNA2,NUP210,PSMA6,ATP2A2,PIN1,DUT,RAB4A,DNM2,NSFL1C,CDKN1B,CDC25B,ARID4A,HTRA2,CDC37,PBK,E2F3,MKI67,RNPS1,RRM2,SLBP,CDC6,CDCA2,BRCA1,USP22,PKMYT1,CCNF,VDAC1,SLC25A5,RAB5B,HSPA4,CCDC14,TIMM29,SAFB,E2F4,GADD45B,MAP4,CEP55,UHRF2,GORASP1,CDT1,CUTA,GADD45G,EPN1,RACGAP1,CDK13,NCAPG,TMEM165,SCYL2,SPAG5,LMNA,FBXO5,PTPN2,RPA2,CCNK,RB1,ERH,CCP110,HUWE1,ZNF746,PRC1,BCL2,FBL,ATP6V0D1,EEF1D,STAU1,TK1,PLEC,KIF11,RPA1,TSC1,GOLGA2,BIRC5,CCDC6,TFDP1,CDCA5,PML,USP32,E2F1,ZRANB2,NDE1,CDK2,CCNB2,ESPL1,ANAPC4,IFI16 |
| 7.806e-16 | -34.79 | MODULE_114 | MSigDB lists | MODULE_114 | 310 | 103 | 17377 | 2626 |
RHOG,CHMP2A,RPLP2,DYNLL1,GYG1,FKBP2,OAT,STMN1,PCBP1,BCAP31,RPL11,RPL23A,RAD23A,ATP6V0B,PCNA,PSMA6,TRA2B,STRAP,MTPN,GPX4,CDC37,RPL29,SEC61B,RPL35,RBX1,SNRPB,RPL38,PSMB7,TMEM147,NDUFB1,VDAC1,SLC25A5,EIF3G,RPS9,RPSA,EIF3H,NSA2,EIF3K,HINT1,RPS27A,PSMD8,RPLP1,UQCRH,BTF3,SNRPG,FAU,AP2S1,MYL12B,ATP6V0E1,PPIB,NDUFV2,COX5B,RPS2,C19orf53,CDC40,PHB2,DAP,SRGN,NACA,GADD45G,CIB1,RPL15,NDUFA4,RAB11A,HLA-A,NDUFS4,RB1,EXOSC7,RPL17,DAD1,H2AFY,RPL19,MRPL21,PPA1,PABPC1,EEF1D,ALDH9A1,ABCC1,STAU1,RNASEH2C,TIMMDC1,MAPKAPK3,RPS10,RPL6,LDHA,RPL8,RPS24,RPL27A,CCT8,PRDX1,ECH1,SDHB,PFDN5,TPD52L2,NAP1L1,KPNA4,RPL32,MAGT1,LRPPRC,MDH1,ACADM,NDUFS5,HIGD2A |
| 8.762e-16 | -34.67 | CUL2 (cullin 2) | protein interactions | 8453 | 439 | 138 | 17029 | 2761 |
TXN,HNRNPAB,ST13,SNRPD3,EDRF1,RBM4,PABPC4,ANKRD39,RPL23A,ZER1,PCNA,POP7,TRA2B,TFG,PCBP2,CARM1,PLK1,COPS8,SNRNP200,RBX1,VHL,SNRPB,HNRNPF,BRCA1,DCUN1D5,SLC25A5,DHX15,DPYSL3,TBC1D17,TIMM13,LUC7L3,RPS14,CAB39,ACTB,COPS6,PTOV1,EWSR1,UBXN1,DHX9,TIA1,RPL15,PRPF39,ARID1B,LRRC14,DDX56,SMC3,MED8,RTCB,MSH2,CTPS1,YBX1,RBM3,MRM3,PABPC1,EEF1D,EIF5A,RPL6,RPS24,ARID1A,ADRB2,PKM,ABCF1,RHOB,XRCC5,RPL36,CAND1,SDHB,PFDN5,NAP1L1,SYNCRIP,ACLY,SLC16A1,YWHAZ,SMPD4,SNRNP70,HNRNPDL,CDKN2A,RPLP2,LAGE3,ATP6V1B2,PCBP1,SDHA,RPL11,HNRNPA2B1,SAP130,GRSF1,NSFL1C,TARDBP,RNPS1,CUL3,CIRBP,RPL38,SLBP,PFKFB3,DNAJA1,TRIM28,RPS9,DDX17,SRSF1,DNAJC10,HNRNPR,RPLP1,FUS,TUBB,UNK,RPS2,SRSF6,AGO2,BRAP,DCUN1D4,TUT4,TMCC3,FEM1B,COPS7B,RPL19,UBE2M,HNRNPM,KAT2A,PPP1R21,RPL8,ILF3,TUFM,RPL27A,SNRPA,POLR2A,PRDX1,SH3GLB1,HSPA1B,PDCD6,ATP6V1D,KEAP1,PRDX3,HNRNPH3,TFE3,KHSRP,DDX5,SRSF3,FAF1 |
| 9.725e-16 | -34.57 | UBL4A (ubiquitin like 4A) | protein interactions | 8266 | 296 | 104 | 17029 | 2761 |
RAB14,SARNP,TXN,HNRNPAB,RPLP2,MOGS,SNRPD3,CDIPT,PCBP1,APP,BCAP31,PABPC4,CD320,RPL11,RPL23A,HNRNPA2B1,SPINDOC,PA2G4,RAB8A,RAB35,DUT,CS,RPN2,TECR,LRRC59,CCAR1,PCBP2,CDC5L,RPL29,SEC61B,RPL38,HNRNPF,DDX20,NDUFA7,RAB1A,SLC25A5,RPS9,RPSA,CLNS1A,GEMIN5,SUGP1,KIF2A,HSPA4,JAK1,SURF4,TMED10,HNRNPR,RPS27A,RPS14,CORO1C,RPLP1,PQBP1,OGT,KPNA2,ACTB,FUS,RPS26,TUBB,USP13,PPIB,RPS2,PHB2,UBXN1,CERK,RPL15,NDUFA4,ATP5F1B,NPLOC4,RB1,ERH,RPN1,NDUFA2,HUWE1,RPL19,GEMIN4,PABPC1,HNRNPM,TMED2,SPTAN1,LDHB,FDFT1,RPS10,RPL6,RFXANK,RPL8,ILF3,TUFM,RPS24,RPL27A,PRDX1,MAPK3,HSPA1B,RPL36,SYNCRIP,RPL32,CDCA7L,PGRMC1,ACAT1,KHSRP,ASNA1,ATP5F1A,SNRNP70,APOL2,FAF1 |
| 9.972e-16 | -34.54 | GO_REGULATION_OF_CELL_CYCLE_PHASE_TRANSITION | MSigDB lists | GO_REGULATION_OF_CELL_CYCLE_PHASE_TRANSITION | 311 | 103 | 17377 | 2626 |
ZNF207,UBE2E2,GPR132,CSNK2A1,SMARCA4,CUL1,SIRT2,CCNB1,APP,FANCI,MDM2,PCNA,PSMD1,CCNA2,PSMA6,NEK6,KIF14,CDKN1B,ANAPC7,ECD,CTDSP2,CARM1,CDC5L,PRPF19,PLK3,PLK1,BRD4,PSMA8,BTG2,PSMB7,CUL3,CDC6,SOX4,CDC23,ANLN,RAB1A,PSMB9,RAD51C,CDC16,RPS27A,PSMD8,PSMD3,E2F4,NSMCE2,XRCC3,CHEK2,TFDP2,GEN1,PSMC1,CLSPN,PHB2,GORASP1,TCF3,CENPF,BLM,PSMD9,RAB11A,CDC73,MAD2L2,CNOT3,FBXO5,RPA2,RFWD3,PSMD2,RB1,PTEN,CENPJ,FBXO7,BRD7,H2AFY,GTSE1,BCL2,KNTC1,CNOT6L,TGFB1,PPP1R9B,ADAM17,PRKDC,PSMA1,ANAPC2,MEN1,PRMT2,PSMB3,RBM38,PSMC4,CDC27,GOLGA2,BIRC5,CDCA5,TFDP1,FAM83D,E2F1,PML,PKD2,CNOT6,ZNF830,CDK2,UBE2C,ESPL1,TERF1,CDKN2A,DDB1,ANAPC4 |
| 1.004e-15 | -34.53 | MILI_PSEUDOPODIA_HAPTOTAXIS_DN | MSigDB lists | MILI_PSEUDOPODIA_HAPTOTAXIS_DN | 622 | 170 | 17377 | 2626 |
TMED7,TMEM184B,PRKCSH,TMEM41B,PPP1R15B,PHRF1,TRIM11,MOGS,TMEM109,ABCB10,SLC29A1,PLXNA1,FKBP2,CDIPT,S1PR2,UBE2I,SLC20A1,CMTM6,ANKRD39,NOL11,IL6ST,RNASEK,SRI,ZFYVE27,KIF22,TAF5L,RNF26,PTPRK,ABCC5,PLK1,TMEM115,ATG9A,ESYT1,ICMT,SLC50A1,ALG3,TRAM2,SPATA2,TMED10,STT3A,NRM,ITGB1,OGT,ST3GAL2,PIEZO1,E2F2,RTN3,KIAA0100,TM9SF4,PHB2,TRIO,ANKH,B4GALT1,ZNRF3,PSEN1,CNOT3,GNS,RNF121,RPN1,DAD1,PPIL2,ATP6V0A2,SLC27A4,ORAI1,CTR9,TNRC18,FAM171A1,ABCC1,NAGPA,SIGMAR1,CREG1,TSPAN31,ERLIN1,TYW1,RPS10,GBA,RPS24,PLEC,SYVN1,ADRB2,ARID1A,LY6E,PTTG1IP,MATR3,AKAP1,PTPRF,ORMDL2,TTC13,FAM83D,SLC16A1,KCTD7,TRIM41,CKLF,SYS1,GPR89A,SLC2A1,SLC39A13,TMEM97,PLAGL2,TM9SF3,SLC35B2,LCLAT1,GLRX3,BCAP31,EXT2,SEC11A,APLP2,ATP6V0B,FBXL6,ATP2A2,CLCN6,CABLES2,LMAN1,MINPP1,PDIA6,FAM3A,ANKLE2,ATP13A1,ERMP1,TIMP2,OAF,BTG2,RNPS1,ATP6V0A1,PKMYT1,BICD2,RPS9,TMEM201,ATP1A1,DDOST,SURF4,SEC61A1,PROSER1,CANT1,NCLN,SCARB1,TMEM101,SLC22A23,PDCD11,TMEM33,CDS2,SCAMP3,TMBIM4,SLC41A1,B4GALT5,UBE4A,MFSD10,EBP,SPPL2A,AHSA1,SLC35B4,SLC38A10,CNPY3,TGFB1,B3GALT6,ELOVL5,ADAM17,MLEC,MEN1,SPPL2B,SLC19A1,TTLL4,GLG1,WDR62,PLOD3,CD81,ARHGAP23,GPR89B,IPO4,ESYT2 |
| 1.036e-15 | -34.50 | protein-containing complex assembly | biological process | GO:0065003 | 1515 | 342 | 17256 | 2622 |
MAX,PDCD6IP,NDUFB6,ZDHHC8,CUL1,USP39,CCNB1,OAT,MIS12,RPL23A,NAPG,SNUPN,DNAAF2,RAD23B,DNM2,TRA2B,AP2B1,NUP153,TFG,SRSF10,USO1,DDX20,MCFD2,MCM2,FOXRED1,CLNS1A,EIF3A,STOML2,AHNAK,WAS,MID1IP1,SMAD2,BRD2,TMED10,RPS27A,PSMD8,RPS14,LUC7L3,AXIN1,EIF2D,RRS1,SMAD1,SLC25A33,NDUFV2,DHPS,PRKAA1,DHX9,RRM1,DNAAF5,KCTD17,B4GALT1,PRPF39,PSMD9,CDC73,NDUFS7,MCTS1,NDUFS4,NDUFAF6,TFAP4,CD59,TMEM250,FKBP1A,ATP6V0A2,FBXL7,GEMIN4,NSUN4,PPP6R1,LUC7L2,TMED2,DDX28,SIGMAR1,TSPYL4,RPS10,SEPT8,CAPZA2,SRSF5,ADRB2,PKM,EIF4H,PATL1,SF3A2,CCT8,FAS,DERL1,CAT,SEC31A,EPRS,GOLGA2,NSF,RBMX,CABIN1,NDE1,PPP6R3,NUP58,ZNF207,NDC1,REPS2,SF3B1,RAF1,EIF3D,CHD1L,RAC1,POMP,EFL1,PRKACA,DECR1,AHCTF1,NUP107,SEPT11,GPX4,CCT2,CDC123,GOPC,CRNKL1,POLR2D,CUL3,CIRBP,RPL38,ATP6V0A1,NDUFA7,RAB1A,TAZ,TRIM28,MAT2A,CENPU,TAF2,RAD51C,CHMP4A,HSPA4,H2AFX,SNRPG,BEND3,PPP5C,CSNK1D,DYNC1LI2,POLQ,NDUFS1,MZT1,ANXA6,SRSF6,TWNK,FLOT1,BLM,RPA2,NDUFA2,NDUFB4,CENPJ,AXIN2,GEMIN6,NAP1L4,NDUFA3,GTF2H2,TK1,TNFAIP3,TMEM126B,WDR18,ADSL,PICALM,FADD,SH3GLB1,RPA1,PML,NAXE,HMGB2,NDUFS5,TAF6,IPO4,DDB1,COX15,NOP2,ST13,UBN1,UQCR10,MCCC1,TAF6L,SNRPD3,BRIX1,SEC16A,CUTC,ATPAF1,EDC3,PRNP,DLG5,ZNHIT6,XRCC2,RPF2,KHDC4,NDUFB9,EIF5,SRPK2,COPS8,SNRNP200,SEPT9,RBX1,BAZ2A,NCK1,SNRPB,PSMG1,LNX2,ANLN,LUC7L,ASF1B,DPYSL3,EPB41,CHAF1A,TRIM4,GEMIN5,UBTF,SEPT1,NIP7,MIA2,ATXN2L,CAB39,STK11,CLU,NAA60,GEMIN7,RPS15,HJURP,GORASP1,TM9SF4,CENPF,NUP205,PRPF18,VASP,MBD2,SSBP3,XPA,CAPZA1,KIFAP3,KNTC1,PREB,HP1BP3,ATP5IF1,TRAPPC9,ACSL3,RPL6,EIF2A,SEPT7,BBS12,CAND1,TSC1,NAP1L1,SNAP23,PRMT7,RUVBL2,RBBP4,EHD4,ECPAS,PDSS2,UNC13C,KCTD7,CHMP2A,NDUFA5,PRKAB1,SART1,CORO7,TOMM20,CYLD,NDUFAF2,XAB2,SLC2A1,SMARCA4,PLAGL2,RPL11,OIP5,ANKRD28,FARSA,RRN3,MDM2,SAR1A,PIN1,PPP6C,CLTB,LMAN1,STRAP,HTRA2,DVL2,CHP1,PRPF19,TUBGCP5,DMAC2,WIPF1,PRPF3,NDUFB1,PEF1,TXNL4A,RPSA,SRSF1,IDE,NDUFA11,ANP32E,CHMP4B,XRCC3,H3F3A,AP2S1,SMAD4,ABCA1,RAD51D,PARD3,TMEM33,MIF,NIFK,SHPRH,CDT1,AGO2,NUP54,TIMM21,CSNK1A1,TUBGCP2,FBXO5,FERMT3,FASTKD3,NDUFV1,SEC24C,ANP32A,H2AFY,NDUFS8,CENPM,PTGES3,ORC3,MRPL11,TTC17,CAMK2G,PPAN,TGFB1,YTHDC1,COA3,NASP,TIMMDC1,SNX2,MEN1,DDX23,MAPK3,SEC23IP,PDCD6,SNAP29,ACAT1,PKD2,CENPT,TAF12,UBE2C |
| 1.070e-15 | -34.47 | organic cyclic compound biosynthetic process | biological process | GO:1901362 | 3234 | 642 | 17256 | 2622 |
ZBTB10,KDM4A,CCNL2,EDRF1,ZNF275,USF1,CIPC,SRSF4,UPRT,CRY2,ECD,ZNRD1,ZNF672,ZNF559,GABPA,MIER2,TOPORS,DIDO1,STOML2,BRMS1,SMAD2,RPS27A,ZNF689,VIPAS39,TFDP2,SMAD1,E2F2,ZNF75A,PFKP,SLC25A33,SSRP1,HIVEP3,DHX9,EZH1,CDC73,MCTS1,TFAP4,INTS7,ZNF326,FOXN2,CPSF4,SRSF11,ETV3,FOXK1,RB1CC1,ZMYND11,MYBL2,USP10,BCLAF1,SRSF5,CBFA2T2,ELK1,POLR2J,ETS2,SETD3,CNOT6,PLPP6,SGF29,ZNF296,KARS,SARNP,TRERF1,IVNS1ABP,PTTG1,RMI2,CREBL2,ZNF267,SLC35B2,INO80E,SAFB2,RCOR3,TCF19,ZNF420,SP100,ZKSCAN1,MTA1,DUT,GMEB1,NABP1,INTS12,ZNF226,ATF2,RPRD1B,CGGBP1,PDCL3,ADCY7,CPNE1,POLR2L,EID1,KAT7,INTS13,WBP2,POLR2D,RNPS1,E2F3,ATP6V0A1,MEF2D,DDX17,TAF2,CHCHD3,HIPK2,PDXK,SNRPG,PPP5C,ZBTB11,COMMD10,GALK1,ZNF786,ZNF445,SRSF6,HABP4,JMJD6,ATP5F1B,WDR5,ETS1,PMVK,NEXMIF,ZNF92,NEIL2,RPA2,ZBTB45,ERH,SUV39H2,PPP1R8,ZNF260,PRDM4,ZNF710,GTF2H2,MED22,PDPK1,TK1,GUK1,POLK,ZNF512,LDHA,DDX39A,PDE3B,RPA1,ZNF862,ZNF180,KEAP1,POLE,PITX1,LRPPRC,PML,HMGB2,PARP10,USF2,THAP5,COX15,THOC1,GPBP1L1,GNPDA1,RBM8A,CSNK2A1,SND1,BIRC2,PAPOLA,CREM,LIN9,PCNA,GLIS2,ZNF639,INTS1,ETV6,XRCC2,NOC2L,PPCDC,MYBL1,CCAR1,RYBP,SP3,BAZ2A,RAD51AP1,SNRPB,MRPL12,PBRM1,BRCA1,EAF2,USP21,CHD3,E2F4,ZNF367,DVL1,DHFR2,ZNF45,BEND6,FAM208A,NUDT11,POT1,ZNF564,FUBP1,ZCCHC9,PHB2,CENPF,CTCF,CHCHD2,CDK13,RLF,ASXL2,CNOT11,RSAD1,ARID1B,SUB1,RB1,MLX,MED8,MBD2,SSBP3,ZNF746,CTR9,TIMELESS,MDFIC,ICE2,MAML1,ALDH18A1,PREB,NSDHL,LDB1,AMD1,UTP15,RTF1,ZNF761,IRF5,ZNF174,RXRB,MBIP,PALB2,PRPS2,TBPL1,PRMT7,RUVBL2,ATP5F1A,TRAF7,UGP2,SUCLG1,ARID2,FOXM1,DYNLL1,XAB2,ZNF416,RRAGC,GGPS1,COMMD8,ZNF121,NRF1,ZBTB21,ZNF473,KMT5C,ZNF302,RPAP1,TARDBP,SAP30L,ZNF583,DVL2,KDM3B,POLR2G,ZNF780B,BTG2,CPOX,NFATC2,KDM1B,SRSF1,ZNF700,RBL1,MAFK,ZNF436,DNAJC17,XRCC3,NCOA1,SLC25A39,SMAD4,RAD51D,INTS2,SLC30A9,CTDP1,NADSYN1,NIFK,CDC40,MTERF1,AGO2,ARID5A,GTF3A,NKRF,PAGR1,RMI1,WRNIP1,IRF4,SS18L1,PTGES3,POLR1B,RNLS,RBM15B,RPRD1A,HMGN5,ZNF202,ZMYM5,TOP3A,PCGF1,BIRC5,L3MBTL3,TFE3,CDCA7L,BBX,E2F1,IMPDH1,RBPJ,TAF12,NR2F2,PGAM1,HIPK3,IFI16,PPCS,MAX,ZNF496,TXN,CXXC1,NANS,CCNB1,OAT,COMMD6,POLR3K,MYEF2,PA2G4,NOL11,FIZ1,ZNF200,TAF5L,SLC26A2,ZNF800,DNMT1,CDC5L,ZNF524,KLF10,ELOA,AMDHD2,USP22,CBFB,RFC2,PRIM1,IWS1,HHEX,BRD2,DHTKD1,BTF3,ARRB2,CCDC59,HDAC2,PTOV1,COX5B,EWSR1,POLR2K,PRKAA1,RRM1,NOTCH2,PMF1,SUPT7L,ZNF518A,ZNF79,VPS25,NPLOC4,CNOT3,YY1AP1,LHX8,KLF16,ATIC,HDAC7,CTPS1,ATP6V0A2,CYC1,EEF1D,TERF2,FDFT1,PHF10,ZNF84,PRIM2,ELL2,ZNF574,DCTD,ARID1A,PKM,KDM3A,TWISTNB,PHF6,XRCC5,ADSS,ZNF777,SERTAD2,ZFP92,DCK,RBMX,MED15,ACLY,CEBPG,PIAS2,GPI,YY1,RNF14,NRBP1,NUDT3,ZNF511,ATXN3,ZBTB37,SUZ12,UROD,ADPGK,TERF2IP,SPINDOC,FLAD1,ZNF75D,KDM2A,UCHL5,LPIN2,ADCY9,CDK12,SAP30,BRD4,RFC3,ERF,DRAP1,SLBP,ELP4,EDF1,POLG2,GAR1,TRIM28,CENPU,SUPT16H,PRDM11,VEZF1,RAD51C,ZNF282,HINT1,SAFB,GUCY1B1,STAT1,ATF6,BEND3,EYA2,ATMIN,POLQ,POU3F2,NCOR2,DEPDC1,TWNK,MECP2,TCF3,MYNN,ARGLU1,BLM,SPR,FOXO3,HMG20A,MAD2L2,EBP,GTF2F1,WWP2,CCNK,ELP5,CARF,CITED2,CREB1,CNOT6L,NCOA2,TSHZ1,ZFP64,KAT2A,ILF3,RFXANK,ADSL,KLF6,COMMD4,POLR2A,CBX3,ZHX1,ATP5MC3,TFDP1,NAXE,KHSRP,DDX5,TAF6,PURA,RORB,CCNC,POLA2,ADA2,ZNF76,IER2,KMT2E,PHRF1,ZNF107,SIRT2,TAF6L,SNRPD3,COMMD5,MAPK14,ATP5PF,SNAPC4,ZNF696,MBD4,EIF4A3,JAZF1,PHTF1,AKR1B1,ZBTB22,TCEA1,OGG1,ARID4A,CARM1,ELOF1,DEAF1,RIOX2,RRM2,SOX4,KMT2C,PRPSAP1,ASF1B,UBTF,PAF1,BRWD1,PQBP1,CRCP,BAZ1B,ZNF268,CHEK2,STARD3NL,ZNF768,NACA,MED13L,MEF2A,THRAP3,SRRT,TTF1,LYAR,DTL,NFATC3,ZNF449,MED10,ZNF335,BUD31,YBX1,ACAD8,ZNF189,VOPP1,ATP5IF1,POLR2I,TSTA3,NUDT4,CIC,SLTM,DAPK3,ISG15,UAP1,NFIL3,NUP62,ZFP90,DNPH1,RBBP4,NIPSNAP2,HNRNPDL,ADNP2,ZBTB24,MBD1,TCF12,MMACHC,ASH1L,GNPNAT1,MPHOSPH8,UCK2,SMARCA4,UCK1,PLAGL2,NSD3,IRF3,CHD1,MXD1,MEAF6,SAP130,RRN3,CD3EAP,AKAP8,CYB5R1,CHTOP,UTP4,TMEM14C,ZNF770,RLIM,CSTF1,POU2AF1,CGAS,ZNF500,PCGF6,ATXN1,OGDH,MBD3,ZNF317,STAT6,ARNTL,SCARB1,AKNA,BRD9,MAPK1,CBX4,NAT14,DNAJC2,ZNF316,EYA1,SCYL1,KLF13,PAWR,MXD4,HDDC2,GART,KMT5A,NABP2,ANP32A,BRD7,STAT3,MYO5A,AMPD2,SAMD4B,TGFB1,GTF3C6,PSPC1,HELB,MIER1,NADK2,POLR3GL,RCOR1,MEN1,ATP5MF,ZNF407,SYMPK,TFEB,MAPK3,CNOT9,ATAD2,KMT2B,ACAT1,SRSF3,ZMIZ1,TERF1 |
| 1.108e-15 | -34.44 | GO_SINGLE_ORGANISM_CELLULAR_LOCALIZATION | MSigDB lists | GO_SINGLE_ORGANISM_CELLULAR_LOCALIZATION | 863 | 218 | 17377 | 2626 |
POLA2,PDCD6IP,NUP188,MTX3,TSC2,AGRN,AP3M2,KIF2C,CCNB1,SEC16A,BECN1,SSR1,RPL23A,KIFC1,CDK5,RAB8A,SNUPN,CDC42,TIMM23,ATG3,DPYSL2,AP3S2,DNM2,ZFYVE27,KIF22,TFG,SEH1L,TIMM50,SRP72,USO1,AKT2,EZR,NUTF2,MCFD2,ICMT,OPTN,RPL37,TRAM2,TIMM13,TMED10,RPS27A,RPS14,MAP4,ITGB1,OGT,KPNA2,ROCK1,VPS4A,DVL1,RRS1,CLN3,RPS26,NMD3,LONP2,RPS15,DNAJC5,GORASP1,PHB2,SEC61G,NKD2,RPL15,KIF23,MEF2A,RAB6A,PSEN1,RAPGEF6,VPS25,NUP205,SPAG5,LMNA,ATG4A,CD59,PPIL2,FBXO7,ARL6IP1,TNPO3,KIFAP3,PPP6R1,NUP85,SYTL3,TMED2,PREB,NAGPA,TIMM8B,GCC2,TRAPPC9,RPS10,RPL6,SSR2,RPS24,MTX1,TOMM40,PTTG1IP,RPL36,SEC31A,SCARB2,GOLGA4,FNTA,KPNA1,GOLGA2,NSF,SNAP23,CDCA5,NUP62,PPP6R3,NDE1,TOB1,CHMP2A,TOMM20,SYS1,RPLP2,RAB11B,ACTR3,RAC1,ANK3,VTI1A,MYH9,LYN,RPAIN,RPL11,ANKRD28,MOAP1,KIF14,NUP107,PPP6C,TNPO2,LMAN1,F2R,GCC1,DCTN1,RPL29,PSRC1,RPL35,SEC61B,RAB7A,CUL3,RPL38,NUSAP1,NUP155,BICD2,CDC23,CHMP2B,RAB1A,RPS9,RPSA,TMEM201,CHMP4A,PEX5,HSPA4,SEC61A1,TIMM17A,TULP3,ARNTL,CEP55,RPLP1,CHMP4B,FAU,MAPK1,SMURF1,TSPAN5,PARD3,CSNK1D,KIF3B,RPS2,RAE1,EYA1,DCTN2,NUP54,CDCA8,FLOT1,ARF1,AP3S1,RAB11A,WRB,PIP5K1C,KIF5B,RPL17,SEC24C,ARHGEF2,RPL19,STAT3,MTX2,PACS2,MYO5A,TGFB1,PPP3CA,KAT2A,ASPM,DENND4C,RPL8,PACS1,RAB3IP,WDR81,RHOT1,RPL27A,MACF1,RHOT2,SH3GLB1,MAPK3,MFN2,HGS,KPNA4,KIF18A,SEC23IP,RPL32,GOLGA7,OSBPL8,SNAP29,PML,LRPPRC,FAM126A,ASNA1,SSNA1,CHMP7,TERF1,ESPL1,IPO4,SNAPIN |
| 1.171e-15 | -34.38 | regulation of cell cycle process | biological process | GO:0010564 | 753 | 197 | 17256 | 2622 |
FGFR1OP,MAX,UBE2E2,PDCD6IP,GPR132,KMT2E,CSNK2A1,CUL1,SIRT2,CCNB1,BECN1,FANCI,CDK5,CALM2,CDKN2C,PCNA,PSMD1,NEK6,CDC42,ECD,CDC25B,TACC3,CARM1,RYBP,PLK1,PLK3,RBX1,AKT2,EHMT1,MKI67,MRNIP,RRM2,CDC6,LRP5,AURKB,BRCA1,CCNF,ANLN,SOX4,PAF1,RPS27A,PSMD8,E2F4,ZNF268,CHEK2,VPS4A,TFDP2,SLF1,PSMC1,SLC25A33,MAPRE1,CLSPN,PHB2,CENPF,KIF23,CTCF,HAUS4,RACGAP1,CDK13,PSMD9,CNOT11,CRLF3,HAUS2,CDC73,CNOT3,SPAG5,DDRGK1,DTL,TFAP4,PDXP,RB1,SMC3,CCP110,FBXO7,MSH2,BCL2,FBXL7,KNTC1,MCPH1,TERF2,PSMA1,DAPK3,PSMB3,PSMC4,HAUS8,PCM1,CDC27,ODF2,CDCA5,FAM83D,NUP62,CNOT6,NDE1,ZNF830,RBBP4,CDK2,CDKN2A,ZNF207,CHMP2A,FOXM1,POC1A,SUZ12,DYNLL1,PTTG1,RMI2,TPX2,BCL2L1,PRKACA,APP,PSMA6,MDM2,BABAM2,AHCTF1,PIN1,KIF14,CDKN1B,CEP63,CTDSP2,RPRD1B,DCTN1,PSRC1,BRD4,PSMA8,BTG2,TAOK1,PCGF6,PSMB7,CUL3,NUSAP1,PKMYT1,CDC23,CHMP2B,PSMB9,RAD51C,CDC16,RBL1,NSMCE2,PSMD3,UHRF2,CHMP4B,XRCC3,GEN1,TUBB,CSNK1D,MIF,KIF3B,PKP4,KLHL21,RAE1,MECP2,CDT1,DCTN2,CDK2AP2,BABAM1,BLM,PAGR1,RAB11A,MAD2L2,FBXO5,RFWD3,CCNK,RPA2,PSMD2,PTEN,CENPJ,PRC1,AXIN2,GTSE1,H2AFY,BRD7,CNOT6L,TGFB1,PPP1R9B,ADAM17,RHOA,KAT2A,HMGN5,PRKDC,PRMT2,MEN1,BORA,KIF11,SH3GLB1,HSPA1B,CBX3,CNOT9,TFDP1,E2F1,PML,SSNA1,PKD2,UBE2C,ESPL1,TERF1,SLF2,ANAPC4,DDB1 |
| 1.197e-15 | -34.36 | REACTOME_PROCESSING_OF_CAPPED_INTRON_CONTAINING_PRE_MRNA | MSigDB lists | REACTOME_PROCESSING_OF_CAPPED_INTRON_CONTAINING_PRE_MRNA | 131 | 58 | 17377 | 2626 |
CDC40,NUP188,POLR2K,SF3B1,RAE1,SRSF6,RBM8A,NUP54,DHX9,SNRPD3,PCBP1,METTL3,NUP205,GTF2F1,SF3B2,PAPOLA,HNRNPA2B1,DNAJC8,NUP210,SRSF4,EFTUD2,NUP107,YBX1,NUP153,NUP85,SEH1L,CCAR1,HNRNPM,PCBP2,CSTF1,SRSF11,SNRNP200,POLR2I,POLR2L,POLR2G,SNRPB,RNPS1,HNRNPF,POLR2D,SLBP,NUP155,SRSF5,TXNL4A,SF3A2,SNRPA,POLR2A,SRSF1,DDX23,SUGP1,POLR2J,HNRNPR,RBMX,NUP62,PRPF4,SRSF3,SNRPG,SNRNP70,AAAS |
| 1.372e-15 | -34.22 | KAECH_DAY8_EFF_VS_DAY15_EFF_CD8_TCELL_UP | MSigDB lists | KAECH_DAY8_EFF_VS_DAY15_EFF_CD8_TCELL_UP | 180 | 71 | 17377 | 2626 |
TXN,NDUFB6,GNPDA1,EIF3D,LAGE3,POMP,GYG1,NANS,TCF19,STMN1,REPS1,SSR1,CDKN2C,AP3S2,NDUFB9,KIF22,PDCL3,TACC3,ACSL5,MKI67,MRPL43,RRM2,HTATIP2,NUSAP1,ARHGDIB,RPSA,ASF1B,EIF3K,TIMM13,DDOST,PSMD8,CORO1C,MRPL27,BTF3,PSMC1,COIL,TUBB,CMAS,NDUFV2,PPIB,SMAP1,MRPL42,ANXA6,PHB2,DAP,CIB1,RRM1,RACGAP1,NDUFA4,REEP5,RPN1,MBD2,MCM5,BANF1,FAM89B,PRC1,TAGLN2,SGCB,PRIM2,WDR1,LDHA,KIF11,PRDX1,BIRC5,CDCA5,DBI,ERGIC3,SSNA1,HMGB2,CCNB2,IGBP1 |
| 1.383e-15 | -34.21 | JOHNSTONE_PARVB_TARGETS_2_DN | MSigDB lists | JOHNSTONE_PARVB_TARGETS_2_DN | 308 | 102 | 17377 | 2626 |
TOMM20,TRERF1,GXYLT1,UBR2,ABCC10,TM9SF3,GLUD1,AGFG1,COMMD5,MAPK14,SSR1,CREM,DST,TNFAIP8,IMPAD1,UCHL5,SRSF4,SLC44A1,ANKRD13C,NUP153,RNF19A,TECR,F2R,TMEM14C,SRSF10,CDC5L,USP34,ENPP4,E2F3,WIPF1,GORAB,GALNT7,STK17B,DHX15,SRSF1,TAF2,TRAM2,HSPA4,HNRNPR,C1orf109,PPA2,CBWD1,ANP32E,TSPAN5,TMEM33,PRPF4B,FUBP1,HIVEP3,MUT,C1orf112,SESTD1,SRGN,ADO,CUTA,FAM76A,CDK13,TOP2B,PRPF39,DCUN1D4,CSNK1A1,TMEM165,RRP36,WRNIP1,SLC31A1,C1GALT1,CLIC4,SMC3,TPST1,AXIN2,CYC1,SLC35A1,LUC7L2,SOCS5,IFRD1,ELOVL5,PPP3CA,PRIM2,TCTEX1D2,NET1,NQO2,OXR1,MRS2,ATP2C1,KCTD20,FBXO9,MRPS10,PPWD1,FXR1,CYB5A,SYNCRIP,MAGT1,OSBPL8,PTAR1,NUP62,FAM126A,SRSF3,RBPJ,RBBP4,TMEM14A,FAF1,DEF6,S100PBP |
| 1.385e-15 | -34.21 | GO_MICROTUBULE_CYTOSKELETON | MSigDB lists | GO_MICROTUBULE_CYTOSKELETON | 994 | 243 | 17377 | 2626 |
FGFR1OP,NPHP4,SKA3,PDCD6IP,XIAP,SIRT2,KIF2C,CNTROB,CCNB1,MAP1LC3B,MAPK14,BIRC2,KIFC1,CALM2,DST,ANKRD26,RAB8A,PCNA,NEK6,CDC42,DPYSL2,XRCC2,DNM2,SUCLG2,FNIP2,KIF22,RP2,MAST2,CDC25B,KCNAB2,TACC3,PLK3,PLK1,RPP25,SEPT9,AATF,PBXIP1,FOPNL,NSUN2,KIF15,EZR,CKAP2L,TOPORS,CDC6,AURKB,BRCA1,DIDO1,CCNF,MCM2,SLC25A5,KRIT1,SEPT1,HSPB11,MID1IP1,RAD18,WDR11,KIF18B,CHD3,AXIN1,MAP4,PQBP1,ROCK1,VPS4A,DVL1,SASS6,TRAF5,AAAS,ANXA11,HSPH1,MAPRE1,TMUB1,PPP1R12A,CENPF,DHX9,CIB1,KLC1,KIF23,RACGAP1,HAUS4,PSEN1,HAUS2,SPAG5,DTL,RB1,CEP104,SMC3,CCP110,KIF13B,TIMELESS,KIFAP3,FBXL7,KNTC1,GNAI2,MCPH1,ATP6V0D1,NUP85,ELL2,CAMSAP1,PSMA1,MAP7D1,SEPT7,MAP2K2,CCT8,TWISTNB,HAUS8,MASTL,FNTA,PCM1,CDC27,GOLGA2,ODF2,FAM83D,SLC16A1,NUP62,MDH1,NDE1,CDK2,CCNB2,MZT2B,ALS2,ZNF207,KARS,CYLD,RAB11B,DYNLL1,POC1A,PMS2,OLA1,TPX2,MYH9,NIT2,BCL2L1,PRKACA,STMN1,APP,MEAF6,CLUAP1,STRBP,WDR44,KIF14,MTA1,NUP107,CEP63,RNF19A,RPRD1B,POC5,DNAL4,DCTN1,PRPF19,CCT2,PSRC1,MAPRE2,BIRC3,TUBGCP5,CUL3,NUSAP1,EML4,SERP1,PPP2CA,KIF2A,CDC16,DGCR8,CCDC14,CEP55,REEP4,GEN1,MAPK1,XRCC4,LRP8,DYNC1LI2,RAD51D,TUBB,CSNK1D,KIF3B,CTDP1,PKP4,MZT1,KLHL21,SCYL1,DCTN2,CDCA8,FLOT1,CSNK1A1,NCAPG,IFT27,RAB11A,TUBGCP2,MAD2L2,NEIL2,SAC3D1,JAKMIP1,FBXO5,KIF5B,STARD9,MZT2A,CLIC4,SLC1A4,CENPJ,AXIN2,PRC1,GTSE1,ARHGEF2,IFT46,NCOA2,MYO5A,NUDC,SPTAN1,STAU1,KAT2A,TACC1,ASPM,NEK7,PARP4,JTB,RANGAP1,RAB3IP,WDR81,KIF11,MACF1,SPPL2B,MAPK3,HSPA1B,CBX3,MFN2,YIF1A,NUCB1,KEAP1,NEK1,ATP6V1D,KIF18A,TTLL4,BIRC5,FAM110A,SNAP29,LRPPRC,USP20,PKD2,SSNA1,WDR62,IGBP1,TERF1,ESPL1,BYSL |
| 1.424e-15 | -34.19 | GSE22432_PDC_VS_TGFB1_TREATEDCOMMON_DC_PROGENITOR_UP | MSigDB lists | GSE22432_PDC_VS_TGFB1_TREATEDCOMMON_DC_PROGENITOR_UP | 184 | 72 | 17377 | 2626 |
TMED7,ATP6V1B2,MRPL19,TMEM69,RAP1A,PCNA,PIN1,POP7,TXLNA,NUP107,MRPL34,AKR1B1,TRA2B,C8orf59,AHCYL1,ATF2,LRRC59,ARL5A,PCBP2,EXOSC6,HARS,SNRPB,NSUN2,TMEM216,RNPS1,NUP155,ABHD11,NUTF2,GFER,DHX15,RPSA,TAF2,TIMM13,LSM6,CHCHD1,PPA2,RWDD4,BCL7C,KLHDC4,TUBB,PWWP2A,EWSR1,NDUFS1,ADO,RAB23,C19orf25,NUP205,RBM17,GTPBP3,SUB1,NDUFV1,NDUFA2,MED8,AHSA1,MCM5,ORAI1,DDX31,PTGES3,MTX2,ZNF202,BTAF1,SF3A2,TPD52L2,TFDP1,SLC16A1,ASNA1,MDH1,SRSF3,NDUFS5,ARHGAP23,C7orf26,FAM72A |
| 1.464e-15 | -34.16 | regulation of cellular metabolic process | biological process | GO:0031323 | 6296 | 1138 | 17256 | 2622 |
ZBTB10,TSC2,HEXB,CCNL2,RBM4,ZNF275,FBXO22,EEF2K,CDKN2C,USF1,THAP4,RAD23B,DNM2,CRY2,ECD,BAK1,ERCC1,ZNF559,GABPA,EHMT1,HNRNPF,WDHD1,MIER2,ARF4,BOLA3,AHNAK,MID1IP1,SMAD2,RPS27A,OGT,MPV17,RNASEL,SMAD1,ZNF75A,OAZ1,PDCD4,SLC25A33,ZNF720,HIVEP3,CLSPN,DHX9,EIF2AK4,PSMD9,PARN,CDC73,TFAP4,CD59,SMC3,MEGF8,FBXO7,MYDGF,CPSF4,MVP,NUP85,PABPC1,PHKG2,NSUN4,PPP6R1,IFRD1,AGGF1,RBM42,FOXK1,MAPKAPK3,MTA2,GTPBP4,ITM2A,USP10,BCLAF1,ELK1,EIF4H,FNTA,KPNA1,PDLIM1,ETS2,ZNF830,NUP58,ALS2,RHOG,KARS,GGNBP2,NQO1,PTTG1,TPX2,INO80E,DAZAP2,RCOR3,AHCTF1,ZNF420,MTA1,TBC1D14,GMEB1,NSFL1C,ZNF226,GPD1L,ZC3H3,RPRD1B,CGGBP1,PDCL3,CPNE1,ULK3,POLR2L,EID1,KAT7,RPL38,CIRBP,E2F3,POLR2D,HTATIP2,PFKFB3,MEF2D,RAB1A,PPP2CA,VPS26B,CORO1C,PPP5C,USP13,COMMD10,ZNF445,SRSF6,ZFP91,HABP4,FLOT1,ABHD14B,WDR5,NEXMIF,PPP1R3B,RPA2,ZBTB45,PSMD2,PDCD10,ZNF260,LTN1,ZNF710,GTF2H2,MED22,PICALM,SH3BP5,GPS2,PARG,CD81,PARP10,YWHAH,THAP5,AAMDC,FAM129A,TRIM11,RBM8A,ENSA,NENF,SND1,TRIM65,FANCI,PAPOLA,ZER1,PRNP,CREM,TET3,RAB8A,NUP210,GLIS2,IL6ST,NOC2L,EIF5,MTPN,RYBP,PLK1,CELSR2,RBX1,RAD51AP1,ZBED5,CDC6,UBE2V1,PBRM1,EAF2,ODC1,USP21,CHD3,ZNF367,E2F4,ADAM9,KPNA2,DVL1,CLN3,BEND6,FAM208A,POT1,ZNF564,FUBP1,ZCCHC9,PHB2,DNAJB2,CENPF,NKD2,LAMTOR3,CHCHD2,CDK13,DNAJB1,CNOT11,ARID1B,SUB1,MLX,MBD2,SSBP3,ZNF746,ARL6IP1,CTR9,RBM3,ICE2,GLE1,LRSAM1,ACSL3,LDB1,MAP4K3,ZNF761,RBM38,IRF5,RMC1,RXRB,MBIP,ORMDL2,LAMTOR4,NLRC5,RUVBL2,BTBD10,BCCIP,USP7,TRAF7,ARID2,ZNF416,RRAGC,ATP6V1B2,LYN,PCBP1,BCAP31,ZNF121,VAV1,NRF1,PSMA6,ZNF473,KMT5C,ZNF302,PIN1,PPME1,TARDBP,AHCYL1,STRAP,SPIDR,CTDSP2,ZNF583,PRPF19,SNX25,PPIF,KDM3B,BIRC3,POLR2G,ZNF780B,PPIE,NUP155,VDAC1,EIF3H,IDE,RBL1,UBXN2B,FASTK,STK38,UHRF2,CHMP4B,H3F3A,SMAD4,PARD3,BCL2L12,SLC30A9,UNK,MTERF1,AGO2,GTF3A,HMGN3,ARF1,CDK11B,PAGR1,SCYL2,FZD6,RNF5,RBM15B,YTHDC1,RHOA,RPRD1A,HMGN5,BTAF1,PRKDC,PCGF1,TRIM26,PDCD6,NEK1,ATP6V1D,L3MBTL3,BBX,E2F1,RBPJ,TAF12,NR2F2,PGAM1,HIPK3,IFI16,TXN,NUP188,MAX,H2AFZ,TSC22D3,CXXC1,UBE2I,MYEF2,PARK7,GLMP,PA2G4,NOL11,FIZ1,ZNF200,TRA2B,TAF5L,CISD2,SMARCE1,ZNF800,CDC5L,SRSF10,ZNF524,KLF10,SUPT20H,USP22,CBFB,RFC2,EIF3A,ZMYM3,DOT1L,IWS1,MAP3K4,HHEX,MKNK1,BRD2,RPS14,BTF3,SLF1,CCDC59,NMD3,PTOV1,EWSR1,SCOC,POLR2K,GADD45G,VAV2,PRKAA1,CYCS,SUPT7L,ZNF79,ZNF518A,PSEN1,VPS25,YY1AP1,CNOT3,WDR48,LHX8,EXOSC7,PPP4R1,MSH2,DAPK1,PIK3IP1,TNRC18,SOCS5,EIF5A,ELL2,USF3,ZNF574,EXOSC9,ARID1A,ADRB2,C9orf40,FXR1,PTTG1IP,MAP2K2,CCT8,PHF6,XRCC5,DERL1,CAT,PFDN5,HSPBP1,GOLGA2,EPOP,RBMX,MED15,PIAS2,ARAP1,CEBPG,FAM83D,SAMD8,CABIN1,CDKN2A,ZNF511,NDC1,ATXN3,RAF1,EPM2A,SPINDOC,CCNA2,MTMR4,RALB,LPIN2,ADCY9,SOCS6,MRPS27,CDK12,SAP30,ANKLE2,BRD4,CDC123,DRAP1,ELP4,EDF1,PKMYT1,ERC1,SERP1,TRIM28,SUPT16H,EIF3K,ZNF282,CHMP4A,HINT1,CERS6,SAFB,ATF6,BEND3,EYA2,DEPDC1,MECP2,ARGLU1,SECISBP2,POFUT1,HMG20A,WWP2,CCNK,ELP5,PTPN11,AXIN2,FEM1B,CARF,CITED2,MSH6,KAT2A,LONRF3,RFXANK,COMMD4,KLF6,FADD,SH3GLB1,CBX3,ZHX1,OAZ2,PPP1R11,DDX5,WDR91,TAF6,PURA,FAM83G,RORB,ZBED3,CCNC,ZNF76,KMT2E,PTP4A3,COMMD5,ZNF696,JAZF1,TCEA1,DRAM2,CARM1,SRPK2,WDR41,DEAF1,LARS,NCK1,VHL,RIOX2,SREK1,KMT2C,ASF1B,EIF4ENIF1,BRWD1,CAB39,BAZ1B,ZNF268,STK11,CHEK2,CLU,ATP6V0E1,CAPN1,UBE2D3,PPP1R2,PPP1R12A,GORASP1,UBXN1,NACA,PM20D2,THRAP3,RGS2,TTF1,NUP205,LYAR,MED10,MCPH1,ATP6V0D1,ATP5IF1,CREG1,ERLIN1,RPL6,GBA,EIF2A,SLTM,DAPK3,MASTL,KLHL15,NFIL3,SIAH2,YWHAZ,CTSA,EHD4,SNRNP70,TOB1,N4BP2L2,ADNP2,TCF12,PRKAB1,FEZ2,SMARCA4,ORC1,MXD1,USP5,HNRNPA2B1,SAP130,RRN3,UBXN2A,NVL,KIF14,EXOSC1,UTP4,ZNF770,CHP1,POU2AF1,UBQLN4,RNF25,SMU1,PCGF6,ATXN1,GLO1,EDEM2,TOLLIP,MBD3,RPS9,PDHX,HNRNPR,STAT6,ARNTL,MAPK1,BRD9,NAT14,DNAJC2,TRIP12,ZNF316,RAE1,SCYL1,NUP54,PAWR,MXD4,DCUN1D4,PIP4K2A,FASTKD3,FGFR3,KMT5A,DUS2,NABP2,H2AFY,ARHGEF2,ANP32A,ATG13,STAT3,TGFB1,ELOVL5,COA3,PHF20L1,PPP1R9B,DCAF6,PSPC1,HELB,MIER1,RFFL,RCOR1,PRMT2,CDK11A,TFEB,LEMD2,MTMR3,UPF1,KMT2B,CENPT,ZMIZ1,HRAS,SLF2,TERF1,FGFR1OP,MAP3K7CL,KDM4A,XIAP,AGPAT1,EDRF1,PPP1R16B,PABPC4,CDK5,CALM2,CIPC,PSMD1,NSRP1,SRSF4,FNIP2,NUP153,SENP1,MLST8,PLK3,ZNF672,AATF,MCL1,TOPORS,DCUN1D5,PLEKHF2,STOML2,BRMS1,ZNF689,AXIN1,LIMK1,PRDX5,VIPAS39,MLYCD,ATP6V0C,TRIM52,TFDP2,E2F2,LONP2,AAAS,SSRP1,PHF23,EZH1,DDRGK1,MCTS1,PHF14,ZNF326,FOXN2,CYFIP1,ETV3,RB1CC1,ZMYND11,MYBL2,SRSF5,CBFA2T2,CSK,DUSP3,SETD3,CNOT6,RNF139,SGF29,EGLN1,ZNF207,PPP1R37,ZNF296,SARNP,TRERF1,IVNS1ABP,UBR2,WDTC1,MYH9,CREBL2,ZNF267,SAFB2,PRKACA,TCF19,APP,ANKIB1,SP100,ZKSCAN1,DDA1,NUP107,ANKRD13C,MAVS,RNF19A,CLN6,RBM15,ATF2,RNF169,ADCY7,ATP6V1G1,SHOC2,PSRC1,MAP4K4,RNPS1,WBP2,ATP6V0A1,CDCA2,DNAJA1,TAZ,DDX17,CHCHD3,TAF2,HIPK2,RPLP1,TICAM1,FUS,ZBTB11,LRP8,ZNF786,RPS2,TRAK1,JMJD6,GMCL1,AKT1S1,ETS1,ZNF92,SUV39H2,PPP1R8,PRDM4,DCP1A,TPCN1,PDPK1,PPP3CA,TNFAIP3,ZNF512,JTB,ZP3,ZNF862,ZNF180,KEAP1,PITX1,PML,LRPPRC,HMGB2,PSAP,USF2,IGBP1,FAF1,THOC1,AGRN,GPBP1L1,PPP1R15B,CSNK2A1,S1PR2,BIRC2,LIN9,ABL2,PCNA,ZNF639,ETV6,PIK3R2,MYBL1,CCAR1,PTPRK,CDC37,SP3,EXOSC6,BAZ2A,PBXIP1,MRPL12,GMFB,EZR,LRP5,BRCA1,RHEB,OPTN,TONSL,SOCS4,ZNF45,LZTR1,CTCF,PPP3CB,RLF,CRLF3,ASXL2,LRRC14,RB1,MED8,TIGAR,TIMELESS,AFF1,MDFIC,MAML1,PREB,TRAPPC9,UTP15,RTF1,EIF2AK1,KRAS,NFATC2IP,EIF4G2,ZNF174,PSMC4,SYNCRIP,TBPL1,PRMT7,RNF114,CYLD,FOXM1,DYNLL1,SUMO2,DUSP22,COMMD8,RPL11,RAD23A,CSDE1,PDK2,ATP6V0B,ZBTB21,MDM2,TNFAIP8,PDCD2,SAP30L,DVL2,TIMP2,PSMA8,BTG2,NFATC2,KDM1B,USP36,SRSF1,DNAJC10,ATP1A1,CLK3,SCAP,ZNF700,TIMM17A,PSMD3,MAFK,DNAJC17,ZNF436,PLGRKT,NCOA1,ZNF146,CTDP1,MIF4GD,DAP,CDT1,ARID5A,NKRF,CSNK1A1,TFRC,WRNIP1,PTPN2,IRF4,SLC35B4,SS18L1,PTGES3,ZNF202,ZMYM5,BIRC5,TWSG1,TFE3,CDCA7L,GLG1,PKD2,UBE2C,ZNF496,YTHDF3,CCNB1,EIF1B,COMMD6,RIC1,PARPBP,CDC25B,MAST2,PLCL2,DNMT1,SEH1L,AKT2,PBK,ELOA,MRNIP,DDX20,AURKB,TMED10,PSMD8,TRAF5,ARRB2,ZNF598,HDAC2,SVIP,DDX58,PPIB,HSPH1,GMFG,CHTF18,NOTCH2,PMF1,METTL3,JMY,NDUFS4,CFLAR,FKBP1A,MEX3C,KLF16,HDAC7,ATP6V0A2,PIKFYVE,LPCAT1,GNAI2,EEF1D,TERF2,PHF10,ZNF84,NOA1,PIP4K2C,KCTD20,CYFIP2,KDM3A,PSMB3,FAS,EPRS,SERTAD2,ZNF777,NSF,ZFP92,QARS,ACLY,PPP3R1,TCOF1,MAP3K5,PPP6R3,YY1,CDK2,RNF14,ZC3HAV1,DNMT3A,RWDD1,ZBTB37,CAST,SUZ12,RPS6KA1,EIF3D,RAC1,MAGED1,PAIP2,TERF2IP,CRKL,APLP2,ZNF75D,KDM2A,SHC1,UCHL5,CDKN1B,CCT2,RFC3,ERF,TAOK1,CUL3,H2AFV,PSMB9,CENPU,SOCS7,PRDM11,VEZF1,PPP2R5A,STAT1,H2AFX,TRIM32,ATMIN,CSNK1D,RHEBL1,POLQ,POU3F2,NCOR2,TCF3,BABAM1,MYNN,BLM,FOXO3,MAD2L2,GTF2F1,RBM17,PTEN,CREB1,MAP3K14,CNOT6L,NCOA2,TSHZ1,ZFP64,NEK7,WDR18,PARP4,ILF3,TBRG4,MARK2,POLR2A,PRDX1,GNA12,HGS,PRDX3,TFDP1,KHSRP,BRWD3,CPEB2,VPS29,IER2,NOP2,HNRNPAB,NF1,UBN1,DNAJC24,ZNF107,SIRT2,TAF6L,UBQLN2,MAPK14,BECN1,SNAPC4,RAP1A,CYREN,EIF4A3,METTL14,PHTF1,PPP1R12C,SRI,ZBTB22,OGG1,ARID4A,TRIM14,ELOF1,COPS8,TRIM8,RRM2,SOX4,ABHD5,UBTF,GEMIN5,PAF1,PQBP1,ROCK1,RPS26,PSMC1,TBC1D12,ZNF768,CIB1,MED13L,TIA1,MEF2A,SRRT,RHBDD1,APOPT1,NFATC3,ZNF449,ZNF335,BUD31,YBX1,BCL2,ACAD8,HP1BP3,ZNF189,VOPP1,CIC,OXR1,PSMA1,ISG15,CAND1,TSC1,RBM25,NSMF,EXOC4,NUP62,ZFP90,RBBP4,HNRNPDL,SMARCD1,ZBTB24,MBD1,ASH1L,MPHOSPH8,IFI27L1,PLAGL2,NSD3,IRF3,CHD1,PAIP1,MEAF6,BABAM2,AKAP8,PARL,CHTOP,F2R,ABI1,HTRA2,MOSPD1,RLIM,FAM172A,ZNF500,PSMB7,NLN,BOLA1,ERBIN,PEF1,ZNF317,TAB2,TULP3,GADD45B,SCARB1,AKNA,SMURF1,PPP2R2D,CBX4,MIF,EYA1,DBF4,KLF13,FBXO5,TANK,PELO,BRD7,SAMD4B,TELO2,HMGN1,ADAM17,PRKAR1B,WDR81,MEN1,ZNF407,SYMPK,SNRPA,HSPA1B,MFN2,MAPK3,CNOT9,PLAA,ATAD2,OSBPL8,ZRANB2,SRSF3,ATP6V1C1 |
| 1.528e-15 | -34.11 | HALLMARK_MYC_TARGETS_V1 | MSigDB lists | HALLMARK_MYC_TARGETS_V1 | 196 | 75 | 17377 | 2626 |
SRM,KARS,H2AFZ,EIF3D,STARD7,CUL1,SNRPD3,PCBP1,PABPC4,HNRNPA2B1,PA2G4,PCNA,PSMD1,CCNA2,PSMA6,IARS,GOT2,DUT,RAD23B,TRA2B,TARDBP,CCT2,RNPS1,GLO1,MCM2,VDAC1,TXNL4A,ODC1,TRIM28,DHX15,CLNS1A,SRSF1,HNRNPR,PSMD8,PSMD3,PPM1G,COX5A,KPNA2,SNRPG,HDAC2,MRPL9,RPS2,PHB2,RRM1,AP3S1,HDDC2,ERH,EXOSC7,EIF2S2,MCM5,CYC1,PTGES3,FBL,PABPC1,IFRD1,TUFM,LDHA,RPL6,RPS10,PSMA1,EIF4H,EIF4G2,SNRPA,PSMB3,CBX3,PSMC4,EPRS,NAP1L1,SYNCRIP,PRDX3,TFDP1,PRPS2,SRSF3,RUVBL2,CDK2 |
| 1.605e-15 | -34.07 | PUJANA_BRCA_CENTERED_NETWORK | MSigDB lists | PUJANA_BRCA_CENTERED_NETWORK | 114 | 53 | 17377 | 2626 |
RECQL,SUZ12,TCF3,RRM1,CSNK2A1,BLM,CNOT3,FANCI,KIFC1,RB1,PCNA,CCNA2,SMC3,DUT,MCM5,MSH2,TIMELESS,CPSF4,DNMT1,SMC4,GINS1,SRSF11,RFC3,NASP,AATF,NCK1,RAD51AP1,SNRPB,PRKDC,MYBL2,BRCA1,SMC2,MCM2,H2AFV,DDX39A,SNRPA,MAT2A,EIF3H,CHAF1A,RPA1,SEC31A,RAD51C,POLE,ZNF330,TFDP1,PRPF4,HMGB2,CHEK2,IDH3B,RBBP4,TFDP2,UBE2C,ESPL1 |
| 1.656e-15 | -34.03 | GO_INTERSPECIES_INTERACTION_BETWEEN_ORGANISMS | MSigDB lists | GO_INTERSPECIES_INTERACTION_BETWEEN_ORGANISMS | 630 | 171 | 17377 | 2626 |
NUP188,PDCD6IP,THOC1,TSC2,UBN1,KDM4A,YTHDC2,TAP1,CUL1,SND1,UBE2I,BECN1,SF3B2,RPL23A,USF1,NUP210,ZNF639,SIVA1,IL6ST,AP1M1,NUP153,SEH1L,PCBP2,CARM1,RBX1,SLC25A5,EIF3A,RPL37,RPS27A,RPS14,ITGB1,ATP6V0C,KPNA2,VPS4A,COPS6,RPS26,RTN3,AAAS,DDX58,RPS15,PPIB,NACA,RPL15,KLC1,CDK13,EIF2AK4,RAB6A,NCKAP1,ITGB5,NUP205,WDR48,CFLAR,TFAP4,RB1,BANF1,MDFIC,CPSF4,LRSAM1,NUP85,MORC3,EIF3L,ZMYND11,RPS10,RPL6,RPS24,EIF4H,ISG15,PSMB3,NMT2,RPL36,XRCC5,DERL1,SCARB2,KPNA1,SYNCRIP,CCDC86,NUP62,MAP3K5,ZC3HAV1,WASF2,USP7,KARS,CHMP2A,RPLP2,IVNS1ABP,DYNLL1,EIF3D,MON1B,SMARCA4,IRF3,BCL2L1,PCBP1,LYN,CHD1,RAD23A,RPL11,CCNA2,MDM2,SHC1,SP100,NUP107,TARDBP,TAP2,MAVS,RBM15,ABI1,PDCL3,CFL1,RPL29,BRD4,RPL35,RAB7A,SELPLG,PSMB7,RPL38,HTATIP2,NUP155,RAB1A,CHMP2B,VDAC1,PSMB9,EIF3G,RPS9,RPSA,IDE,CHMP4A,RBL1,HIPK2,STAT1,H2AFX,RPLP1,CHMP4B,SCARB1,FAU,XRCC4,MAPK1,RPS2,RAE1,NUP54,HLA-A,XPR1,TFRC,WWP2,CCNK,RPL17,RPL19,CREB1,STAT3,PACS2,MSH6,RBM15B,TGFB1,RHOA,KAT2A,RPL8,RCOR1,PACS1,RPL27A,FADD,MAPK3,HSPA1B,HLA-B,KPNA4,RPL32,ZC3H7B,PML,CHMP7,CD81,USF2,DDB1,SNAPIN |
| 1.656e-15 | -34.03 | GO_SYMBIOSIS_ENCOMPASSING_MUTUALISM_THROUGH_PARASITISM | MSigDB lists | GO_SYMBIOSIS_ENCOMPASSING_MUTUALISM_THROUGH_PARASITISM | 630 | 171 | 17377 | 2626 |
PDCD6IP,NUP188,TSC2,THOC1,KDM4A,UBN1,YTHDC2,TAP1,CUL1,SND1,UBE2I,BECN1,RPL23A,SF3B2,USF1,NUP210,ZNF639,SIVA1,IL6ST,AP1M1,NUP153,PCBP2,SEH1L,CARM1,RBX1,SLC25A5,EIF3A,RPL37,RPS27A,RPS14,ITGB1,ATP6V0C,KPNA2,VPS4A,COPS6,RPS26,RTN3,AAAS,DDX58,PPIB,RPS15,NACA,RPL15,KLC1,CDK13,RAB6A,EIF2AK4,NCKAP1,ITGB5,NUP205,WDR48,CFLAR,TFAP4,RB1,BANF1,MDFIC,CPSF4,LRSAM1,NUP85,MORC3,EIF3L,ZMYND11,RPS10,RPL6,RPS24,EIF4H,PSMB3,NMT2,ISG15,XRCC5,RPL36,DERL1,SCARB2,KPNA1,SYNCRIP,CCDC86,NUP62,MAP3K5,ZC3HAV1,USP7,WASF2,KARS,CHMP2A,RPLP2,IVNS1ABP,DYNLL1,EIF3D,MON1B,SMARCA4,IRF3,BCL2L1,LYN,PCBP1,CHD1,RPL11,RAD23A,MDM2,CCNA2,SHC1,SP100,NUP107,TARDBP,TAP2,MAVS,RBM15,ABI1,PDCL3,CFL1,RPL29,BRD4,RPL35,RAB7A,SELPLG,PSMB7,RPL38,HTATIP2,NUP155,CHMP2B,VDAC1,RAB1A,PSMB9,RPS9,EIF3G,RPSA,IDE,CHMP4A,RBL1,HIPK2,STAT1,RPLP1,H2AFX,CHMP4B,SCARB1,FAU,XRCC4,MAPK1,RPS2,RAE1,NUP54,TFRC,XPR1,HLA-A,WWP2,CCNK,RPL17,RPL19,CREB1,STAT3,PACS2,MSH6,RBM15B,TGFB1,RHOA,KAT2A,RPL8,RCOR1,PACS1,RPL27A,FADD,HSPA1B,MAPK3,HLA-B,KPNA4,RPL32,ZC3H7B,PML,CHMP7,USF2,CD81,DDB1,SNAPIN |
| 1.657e-15 | -34.03 | GO_ENVELOPE | MSigDB lists | GO_ENVELOPE | 985 | 241 | 17377 | 2626 |
COX15,NUP188,MTX3,NDUFB6,MRPS15,UQCR10,TMEM109,MCCC1,ABCB10,AGFG1,UBE2I,BECN1,MRPL19,PARK7,SLC25A37,PRNP,DST,FANCL,SNUPN,NUP210,TIMM23,GOT2,INTS1,SLC44A1,HADHB,NDUFB9,NUP153,CISD2,LRRC59,SENP1,MRPL32,SEH1L,TIMM50,BAK1,MRPL12,MRPL43,SLC25A22,MCL1,NUTF2,SLC25A5,FOXRED1,STOML2,TIMM13,MRPL27,NRM,MPV17,COX5A,UQCRH,KPNA2,CLU,SMAD1,MRPL13,AAAS,SLC25A33,ANXA11,COX5B,NDUFV2,MRPL9,PHB2,CENPF,RRM1,NDUFA4,COX4I1,CYCS,XPO7,PSEN1,QSOX2,NUP205,NDUFS7,LMNA,NDUFS4,DTL,BDH1,EI24,TNPO3,YBX1,BCL2,CYC1,GLE1,MRPL48,MRPL40,ALDH18A1,MRPL21,MVP,TNRC18,NUP85,NIPSNAP1,EIF5A,TIMM8B,SIGMAR1,RB1CC1,NOA1,PGS1,TEX10,ACSL3,GTPBP4,MRPL16,MTX1,TOMM40,ABCF1,SFXN5,MATR3,CYB5A,AKAP1,CAT,SDHB,PCM1,KPNA1,COX7A2L,NUP62,MRPL3,CHMP2A,NDUFA5,IMMT,ATXN3,TOMM20,SUCLG1,NDUFAF2,MRPL39,RAF1,MDH2,TOR1AIP1,TMEM97,BCL2L1,SLC25A44,SNN,LYN,SDHA,APP,TERF2IP,MOAP1,CSDE1,MRPL50,AHCTF1,MTA1,NUP107,MRPS27,MRPL34,TNPO2,PARL,MAVS,FAM76B,APOOL,ATF2,RBM15,TMEM14C,HTRA2,ACSL5,PPIF,NXT1,COQ10B,CPOX,VDAC2,HTATIP2,MTMR6,NLN,TOR1AIP2,NUP155,NDUFA7,OGDH,VDAC1,NDUFB1,TAZ,MRPS14,GFER,TMEM201,ANKZF1,CHCHD3,MRPL2,DAP3,MRPL55,CERS6,TIMM17A,TOMM6,CHCHD1,NDUFA11,CHMP4B,ATF6,SLC25A39,TUBB,ZC3HC1,TMEM33,INTS2,DNAJC2,NDUFS1,CDS2,MRPL42,RAE1,NUP54,MRPS26,BRAP,SLC25A12,LETMD1,AGPAT3,GMCL1,SLC25A43,SLC25A36,GSTK1,NDUFV1,NDUFA2,COQ4,NDUFB4,CRAT,MRPL54,NDUFS8,MRPL11,NDUFA3,STAT3,MTX2,S100A6,RNF5,SLC25A1,TIMMDC1,TMEM126B,ABCF2,MRS2,MRPS10,RANGAP1,RHOT1,GUF1,RHOT2,CHCHD6,SH3GLB1,MAPK3,CBX3,MFN2,LEMD2,KPNA4,PDCD6,OSBPL8,LRPPRC,PML,COX8A,ACAT1,AEN,SLC25A19,NDUFS5,CHMP7,HIGD2A,IPO4,FAF1 |
| 1.819e-15 | -33.94 | MEPCE (methylphosphate capping enzyme) | protein interactions | 56257 | 185 | 75 | 17029 | 2761 |
SART1,HNRNPAB,HNRNPUL2,USP39,SNRPD3,SDE2,SF3B2,HNRNPA2B1,DNM2,RPAP1,MOB1A,PCBP2,PRPF19,SRP72,CCT2,SNRNP200,RFC3,SNRPB,RPL38,CUL3,PRPF3,LUC7L,TRIM28,RPS9,DDX17,HNRNPR,LSM6,CLK3,LUC7L3,RPS14,PRPF4,KPNA2,ANP32E,ACTB,SNRPG,DDX42,RPS2,TRIP12,DHX9,CDK11B,CDC73,GTF2F1,KIF5B,EFTUD2,ARHGEF1,ANP32A,YBX1,FBL,UBE2M,LUC7L2,NTPCR,ILF3,RANGAP1,KIF11,MATR3,CCT8,MAP2K2,ISG15,ZFR,DDX23,CAND1,CNOT9,MAGED2,KPNA1,TRIM26,SYNCRIP,RBMX,YWHAZ,CTSA,DDX5,RUVBL2,SRSF3,SNRNP70,ARHGAP23,PURA |
| 1.847e-15 | -33.93 | MORF_PTPN11 | MSigDB lists | MORF_PTPN11 | 104 | 50 | 17377 | 2626 |
RMND5A,NDUFV2,MAPRE1,H2AFZ,SCAMP3,CHERP,LAGE3,MOGS,CYCS,SNRPD3,PARK7,NUP205,HDDC2,NDUFS4,RAD23A,SF3B2,NDUFV1,SMC3,PTPN11,ANP32A,NDUFS8,TARDBP,PTGES3,PDIA6,IFRD1,CDC123,EID1,NSDHL,VDAC2,ILF3,DNAJC9,SLBP,UTP3,VDAC1,CBFB,RFC2,KIF11,CCT8,TRIM28,TARS,SRSF1,SDHB,HNRNPR,DHX16,MFAP1,PPM1G,MPV17,BAZ1B,KHSRP,MRFAP1L1 |
| 1.910e-15 | -33.89 | NCL (nucleolin) | protein interactions | 4691 | 361 | 119 | 17029 | 2761 |
NOP9,USP7,SART1,DDX47,CYLD,SUZ12,EIF3D,MOGS,CUL1,CSNK2A1,SMARCA4,USP39,EBNA1BP2,BRIX1,RPL11,RPL23A,PA2G4,MDM2,CD3EAP,RPF2,CRY2,ANAPC7,TARDBP,MYBL1,FTSJ3,SRPK2,CDC5L,FYTTD1,SNRNP200,RFC3,SEPT9,VHL,NSUN2,CUL3,SREK1,PRPF3,BRCA1,SMC2,MCM2,EIF3G,RPS9,DHX15,EIF3A,CHCHD3,DAP3,HNRNPR,DGCR8,ZNF689,RPS14,U2SURP,RPLP1,H2AFX,COPS6,RRS1,H3F3A,ARRB2,SMURF1,RPS26,UNK,RPS15,RPS2,MRPS26,DHX9,RPL15,CTCF,HDGFL2,ETS1,CDC73,LMNA,GTF2F1,LYAR,RPA2,ERH,SMC3,HUWE1,RPL17,MCM5,ZNF746,YBX1,RPL19,NAP1L4,FBL,PABPC1,MSH6,SLC25A1,TERF2,PPAN,CYFIP1,STAU1,EIF3L,DDX24,RBM42,ABCF2,RPS10,RPL6,GTPBP4,ILF3,RPL8,RPS24,KRAS,EXOSC9,RANGAP1,SRSF5,RPL27A,CDK11A,RPA1,XRCC5,CAND1,RPL36,MAGED2,NAP1L1,CDC27,ACLY,NUP62,SRSF3,YY1,CD81,ZC3HAV1,CDKN2A |
| 1.933e-15 | -33.88 | MORF_PPP1CA | MSigDB lists | MORF_PPP1CA | 158 | 65 | 17377 | 2626 |
KARS,H2AFZ,HNRNPAB,SUMO2,COPE,ENSA,STARD7,AP1B1,CDIPT,PARK7,BCAP31,MBD4,SF3B2,UTP18,RAD23B,PPP6C,TECR,CCT2,POLR2G,CDC123,TMEM147,TRIM28,STOML2,EIF3K,PSMD8,PPM1G,COX5A,SNRPG,PSMC1,AP2S1,COIL,MYL12B,COX5B,NDUFS1,MRPL9,PDAP1,DAP,DCTN2,CTCF,COX4I1,UBE4A,PSMD9,NDUFV1,NDUFA2,ATIC,ARF5,BANF1,BUD31,CYC1,TMED2,EEF1D,HMGN1,POLR2I,JTB,TUFM,SSR2,EIF4H,CBX3,PDCD6,RBMX,COX7A2L,YWHAZ,MDH1,SRSF3,YY1 |
| 1.955e-15 | -33.87 | TARDBP (TAR DNA binding protein) | protein interactions | 23435 | 311 | 107 | 17029 | 2761 |
SART1,CYLD,HNRNPAB,NOP2,SF3B1,HNRNPUL2,YTHDC2,MYH9,SND1,UBQLN2,PCBP1,GNB2,APP,PABPC4,RPL11,RPL23A,HNRNPA2B1,PSMA6,GRSF1,MRPS27,NSFL1C,TARDBP,AHCYL1,PCBP2,CSTF1,CDC5L,PRPF19,SNRNP200,RPL35,VHL,MRPL12,CUL3,GMFB,PRPF3,BRCA1,MCM2,SLC25A5,TRIM28,RPS9,RPSA,DHX57,EIF3H,EIF3A,DDX17,DAP3,AHNAK,HSPA4,HNRNPR,LSM6,RPS14,MAP4,U2SURP,ATXN2L,KPNA2,FUS,TUBB,HSPH1,RPS2,DNAJB2,SRSF6,NACA,AGO2,DHX9,RPL15,NKRF,DNAJB1,SRRT,RPA2,RPL17,ATIC,ZNF746,RRBP1,RPL19,MRPL48,FBL,PABPC1,HNRNPM,LUC7L2,STAU1,PRRC2A,RPL6,RPL8,ILF3,RPS24,USP10,BCLAF1,ADRB2,NDRG3,PATL1,MATR3,ZFR,RPA1,XRCC5,CAND1,UPF1,PDCD6,SYNCRIP,RPL32,ZHX1,RBMX,KHSRP,DDX5,RUVBL2,ATP5F1A,HNRNPDL,PURA,ZC3HAV1 |
| 1.994e-15 | -33.85 | MYC (MYC proto-oncogene, bHLH transcription factor) | protein interactions | 4609 | 637 | 181 | 17029 | 2761 |
MAX,TXN,CXXC1,MOGS,CUL1,CSNK2A1,OAT,UBE2I,FANCI,SSR1,HADHB,NUP153,LRRC59,CARM1,PLK1,SNRNP200,DPM1,VHL,PBK,RIOX2,HNRNPF,DDX20,MCL1,CDC6,BRCA1,SMC2,USP22,CBFB,RFC2,DHX15,ARF4,EIF4ENIF1,SMAD2,TONSL,E2F4,AXIN1,U2SURP,KPNA2,ACTB,HDAC2,FUBP1,HSPH1,CHTF18,TRIO,CENPF,ITGB5,METTL3,COPG2,CDC73,NUP205,LMNA,RB1,RPN1,EFTUD2,CTPS1,MSH2,CTR9,YBX1,BCL2,CYC1,GEMIN4,UBE3C,ALDH18A1,PHKG2,POLR2I,ETV3,DCAF8,NQO2,PSMA1,CCT8,PSMB3,PSMC4,XRCC5,PFDN5,EXOC4,PIAS2,RUVBL2,YY1,SNRNP70,MYO9A,CDK2,MZT2B,CDKN2A,USP7,TCF12,NDUFA5,DNMT3A,SUCLG1,UBR2,RAF1,SF3B1,SMARCA4,ZFYVE21,RCOR3,PCBP1,APP,ZNF121,MXD1,RPL11,SAP130,PIN1,AKAP8,PPP6C,CDKN1B,RPN2,RBM15,CDK12,CCT2,SHOC2,BRD4,RFC3,MKLN1,PPT1,IDH3A,ERBIN,TRIM28,ERC1,USP36,DDX17,CHCHD3,PPP2CA,PPP2R5A,RBL1,PSMD3,MAPK1,TUBB,NDUFS1,TRIP12,EYA1,SCYL1,TKT,SLC25A12,MYO9B,WDR5,FOXO3,TUBGCP2,PNO1,TUT4,WWP2,GTF2F1,FBXO5,CCNK,PSMD2,SLC1A4,HUWE1,PELO,NABP2,PRC1,ARHGEF2,FBL,CAMK2G,MSH6,SLC25A1,SMC4,KAT2A,DDX24,PRKDC,ATP5MF,MEN1,CIP2A,PRDX1,POLR2A,MAPK3,NUCB1,KPNA4,KIF18A,PDCD6,ATAD2,POLE,CDCA7L,LRPPRC,PML,E2F1,TAF12,RBPJ,PLOD3,IDH3B,PARP10,DDB1,IPO4,DDX52 |
| 2.043e-15 | -33.82 | GSE22886_NAIVE_CD4_TCELL_VS_48H_ACT_TH1_DN | MSigDB lists | GSE22886_NAIVE_CD4_TCELL_VS_48H_ACT_TH1_DN | 189 | 73 | 17377 | 2626 |
IMMT,H2AFZ,STARD7,C5orf30,BCL2L1,SNRPD3,UBE2I,PARK7,EDC3,HNRNPA2B1,PSMD1,PSMA6,ATP2A2,NUP107,TARDBP,HTRA2,ERCC1,RFC3,BIRC3,EID1,SNRPB,CPOX,HTATIP2,PKMYT1,PITPNB,CCNF,HSPB11,PSMD8,H2AFX,UQCRH,MRPL13,PFKP,TUBB,CMAS,GALK1,NDUFS1,TRIP12,RRM1,CHCHD2,RACGAP1,MYL6B,FASTKD3,PSMD2,NDUFV1,KLHL5,ARPC5,MCM5,PELO,CLDND1,KNTC1,CYC1,ALDH18A1,SGCB,SMC4,ELL2,ERLIN1,PSMA1,RIT1,FADD,PSMB3,PRDX1,SLCO4A1,MTHFD2,POLE,PRDX3,MFAP1,COX8A,NUP62,CNOT6,HMGB2,RUVBL2,CCNB2,CDK2 |
| 2.065e-15 | -33.81 | rev (p19) | protein interactions | 155908 | 303 | 105 | 17029 | 2761 |
NOP9,DDX47,HNRNPAB,NQO1,CSNK2A1,USP39,AGFG1,C2orf49,PCBP1,KRR1,HNRNPA2B1,ATP2A2,EXOSC1,PPP6C,KIF22,NUP153,RBM15,PCBP2,CDC5L,PRPF19,SNRNP200,SMU1,HNRNPF,DNAJA1,PRKRA,RPSA,SRSF1,DDX17,SUPT16H,PON2,TMED10,HNRNPR,RPS27A,SAFB,CHCHD1,KPNA2,ACTB,ANP32E,FUS,SNRPG,FAU,MAPK1,PDCD11,PPP2R2D,PFKP,TUBB,PRPF4B,PPIB,RECQL,RPS2,EWSR1,MRPL42,SRSF6,DHX9,LMNA,ERH,SUB1,DDX56,EXOSC7,EIF2S2,HUWE1,RPL17,RTCB,TNPO3,ANP32A,MDFIC,NAP1L4,PTGES3,MRPL11,PABPC1,HNRNPM,SPTAN1,EIF5A,PPAN,DDX24,RBM42,PSPC1,PRKDC,AMD1,MRS2,RPL6,ILF3,RANGAP1,PACS1,SRSF5,MPG,ABCF1,MATR3,SF3A2,MAPK3,HLA-B,NAP1L1,KPNA4,KPNA1,SYNCRIP,RPL32,MFAP1,HNRNPH3,NUP62,DDX5,SNRNP70,HNRNPDL,PURA,GPATCH4,DDB1 |
| 2.086e-15 | -33.80 | SRSF1 (serine and arginine rich splicing factor 1) | protein interactions | 6426 | 178 | 73 | 17029 | 2761 |
SART1,TOMM20,CYLD,SUZ12,SF3B1,CUL1,UBE2I,APP,SSR1,EIF4A3,SRSF4,TRA2B,AHCYL1,ZC3H3,CDK12,SRSF10,SRPK2,PRPF19,CDC5L,SNRNP200,CUL3,HNRNPF,SMU1,RNPS1,SREK1,BRCA1,DIDO1,LUC7L,DHX15,SRSF1,DDX17,SURF4,HNRNPR,CLK3,LUC7L3,PRPF4,SMURF1,TRAF5,NKAPD1,PRPF4B,EWSR1,SRSF6,HABP4,GSPT2,DHX9,LMNA,SUB1,HUWE1,EFTUD2,ZNF746,ZNF326,TNPO3,GNAI2,HNRNPM,LUC7L2,SRSF11,YTHDC1,STAU1,ZMYND11,WDR18,SRSF5,MPG,SF3A2,CAND1,SYNCRIP,SNAP23,HNRNPH3,DDX5,SRSF3,SNRNP70,IGBP1,HNRNPDL,HIPK3 |
| 2.180e-15 | -33.76 | SOD1 (superoxide dismutase 1) | protein interactions | 6647 | 328 | 111 | 17029 | 2761 |
KARS,PTMS,PDCD6IP,TXN,HNRNPAB,COPA,PRKCSH,MDH2,EIF3D,SUMO2,RBM8A,HEXB,LACTB2,SND1,OAT,STMN1,PCBP1,PARK7,PABPC4,RAB21,RAP1A,PSMA6,CDC42,EIF4A3,PIN1,SRI,AKR1B1,MAVS,RNF19A,AHCYL1,PDIA6,MTPN,CFL1,GPX4,PPIF,CCT2,LARS,EXOSC6,IDH3A,NSUN2,MRPL12,UBE2V1,GLO1,PITPNB,NUTF2,MCM2,CBFB,TRIM28,MAT2A,EIF3H,EIF3A,OPTN,GLOD4,PPP2CA,HSPA4,ATP1A1,TIMM13,SMAD2,HINT1,PRDX5,CEP55,PDXK,PSMC1,FUBP1,MIF,EWSR1,RAE1,UFC1,NACA,CUTA,TKT,CHCHD2,DNAJB1,SPR,SCYL2,LMNA,KIF5B,FKBP1A,GSTK1,PSMD2,HUWE1,MCM5,BANF1,BCL2,TAGLN2,NAP1L4,PPA1,UBE2M,EEF1D,NUDC,LDHB,EIF5A,PPP3CA,RHOA,LDHA,ADSL,API5,HAGH,CCT8,PRDX1,POLR2A,XRCC5,CAT,EPRS,DBI,ACAT1,YWHAZ,RUVBL2,PSAP,PGAM1,APOL2 |
| 2.686e-15 | -33.55 | REACTOME_CELL_CYCLE | MSigDB lists | REACTOME_CELL_CYCLE | 391 | 120 | 17377 | 2626 |
POLA2,FGFR1OP,MAX,H2AFZ,DYNLL1,PTTG1,CUL1,NUF2,KIF2C,ORC1,CCNB1,UBE2I,PRKACA,MIS12,TERF2IP,LIN9,OIP5,CDKN2C,MDM2,PCNA,PSMD1,CCNA2,AHCTF1,PSMA6,NUP107,CDKN1B,ANAPC7,CDC25B,CEP63,SEH1L,DCTN1,PLK1,RFC3,PSMA8,TAOK1,E2F3,PSMB7,TUBGCP5,RRM2,CDC6,AURKB,BRCA1,DIDO1,PKMYT1,CDC23,MCM2,RFC2,PSMB9,GINS4,PRIM1,KIF2A,PPP2CA,CDC16,PPP2R5A,DSN1,RBL1,RPS27A,PSMD8,E2F4,PSMD3,H2AFX,CHEK2,E2F2,PSMC1,POT1,CSNK1D,TUBB,MCM10,MAPRE1,HJURP,GORASP1,CDT1,DCTN2,DBF4,CDCA8,KIF23,PMF1,PSMD9,TUBGCP2,HAUS2,LMNA,FBXO5,RPA2,RB1,PSMD2,SMC3,CENPJ,MCM5,KNTC1,CENPM,ORC3,NUP85,TERF2,NUDC,GINS1,PRIM2,MYBL2,PSMA1,ANAPC2,RANGAP1,PSMB3,PSMC4,RPA1,KIF18A,PCM1,POLE,CDC27,BIRC5,TFDP1,E2F1,SSNA1,CENPT,RUVBL2,RBBP4,CDK2,CCNB2,UBE2C,TERF1,ANAPC4,CDKN2A |
| 2.701e-15 | -33.55 | GO_RIBONUCLEOPROTEIN_COMPLEX_SUBUNIT_ORGANIZATION | MSigDB lists | GO_RIBONUCLEOPROTEIN_COMPLEX_SUBUNIT_ORGANIZATION | 182 | 71 | 17377 | 2626 |
SART1,XAB2,SF3B1,EIF3D,USP39,SNRPD3,BRIX1,EDC3,RPL11,RPL23A,SNUPN,ZNHIT6,RPF2,STRAP,SRSF10,SRPK2,PRPF19,SNRNP200,CDC123,SNRPB,CRNKL1,RPL38,CIRBP,POLR2D,DDX20,PRPF3,TXNL4A,LUC7L,EIF3G,RPSA,EIF3H,EIF3A,CLNS1A,SRSF1,GEMIN5,EIF3K,NIP7,LUC7L3,RPS14,EIF2D,ATXN2L,SNRPG,GEMIN7,RPS15,CDC40,SRSF6,KLC1,PRPF39,GFM2,PRPF18,MCTS1,KIF5B,GEMIN6,GEMIN4,MRPL11,NSUN4,LUC7L2,PPAN,YTHDC1,DDX28,EIF3L,RPL6,RPS10,BMS1,SRSF5,EIF2A,EIF4H,PATL1,SF3A2,DDX23,PRMT7 |
| 2.729e-15 | -33.53 | MARKEY_RB1_ACUTE_LOF_UP | MSigDB lists | MARKEY_RB1_ACUTE_LOF_UP | 222 | 81 | 17377 | 2626 |
TMEM106C,H2AFZ,NQO1,LAGE3,KIF2C,CCNB1,STMN1,PABPC4,MDM2,PCNA,CCNA2,KIF22,TARDBP,PRADC1,TIPARP,PRPF19,PLK1,KLF10,RAD51AP1,MKI67,RRM2,DNAJC9,NUSAP1,CDC6,BRCA1,SMC2,ANLN,CCNF,H2AFV,BTBD1,ASF1B,PRIM1,KIF2A,HNRNPR,RBL1,LUC7L3,OGT,H2AFX,KPNA2,PPP5C,SASS6,TUBB,HDAC2,FUBP1,GCLM,NSMCE4A,SCOC,CDT1,CDCA3,KIF23,RACGAP1,DTL,SMC3,MCM5,BANF1,EI24,PRC1,AHCY,PTGES3,SLC12A2,HMGN1,TK1,NASP,ZMYND11,PSPC1,HELB,ILF3,ADSL,KIF11,FAS,NAP1L1,BIRC5,RBMX,CDCA7L,TFDP1,CDCA5,E2F1,HMGB2,RBBP4,CDK2,CCNB2 |
| 3.294e-15 | -33.35 | SF3B3 (splicing factor 3b subunit 3) | protein interactions | 23450 | 183 | 74 | 17029 | 2761 |
USP7,SART1,CYLD,COPA,XAB2,SUZ12,SF3B1,COPE,CUL1,SNRPD3,SF3B2,MDM2,EIF4A3,TCEA1,CCAR1,DCTN1,CDC5L,PRPF19,NOL12,PLK1,CCT2,SNRNP200,KLF10,SMU1,RNPS1,CUL3,SREK1,ELP4,PRPF3,BRCA1,LUC7L,DHX15,SRSF1,STOML2,HNRNPR,PRPF4,FUS,ARRB2,TUBB,SMNDC1,UNK,CDC40,THRAP3,SPDL1,SRRT,LMNA,CFLAR,RPA2,SMC3,HUWE1,MCM5,EFTUD2,ZNF746,YBX1,HNRNPM,LUC7L2,SPTAN1,KAT2A,WDR18,SF3B6,USP10,SF3A2,SNRPA,CAND1,RPA1,HGS,SYNCRIP,RBMX,DDX5,ISY1-RAB43,CDK2,CD81,SGF29,SSSCA1 |
| 3.340e-15 | -33.33 | pleura | COSMIC cancer mutations | pleura | 4983 | 910 | 17385 | 2587 |
RAB14,FGFR1OP,KDM4A,PIGQ,XIAP,DHX8,LACTB2,PPP1R16B,ZNF275,FBXO22,EEF2K,CDKN2C,CDK5,NEK6,THAP4,RABGAP1L,RAD23B,SRSF4,MECR,UPRT,NUP153,RNF26,SENP1,PCBP2,MLST8,PLK3,BAK1,ERCC1,RHOBTB3,NRAS,GABPA,MCL1,TOPORS,SMC2,PPFIA3,MCM2,ICMT,RAB22A,ARF4,KRIT1,PWWP2B,TRIM47,AHNAK,SMAD2,MID1IP1,WDR11,RAD18,LIMK1,AXIN1,OGT,RNASEL,FBXL3,TFDP2,SMAD1,E2F2,ANXA11,PDCD4,PFKP,NXT2,SSRP1,DDX42,HIVEP3,CLSPN,GGA1,RHOC,TRIO,RAB23,CERK,TOP2B,HAUS4,ZNRF3,EZH1,EIF2AK4,PDCD7,ITGB5,APH1B,LMNA,MCTS1,ATG4A,DDX56,SLC38A5,RNFT1,INPP5A,MCM5,FBXO7,PHF14,FOXN2,GEMIN4,NUP85,PHKG2,CARS2,SRSF11,ETV3,RB1CC1,DHX29,MYBL2,ITM2A,USP10,BCLAF1,UHRF1BP1,SRSF5,MPG,ELK1,MATR3,RHOB,NCDN,PTPRF,MAGED2,DTWD1,KPNA1,TXNDC16,ETS2,DUSP3,MDH1,SNX14,RNF139,ALS2,EGLN1,RHOG,TRIM41,TRERF1,UBR2,PTTG1,ANK3,CHD1L,TPX2,MYH9,NUF2,PRKACA,KTN1,RAB21,PRKD3,FBXL6,DUT,UBA5,NUP107,CLCN6,ANAPC7,RNF19A,RBM15,RPRD1B,ARL5A,PDCL3,SNX8,GOPC,IDH3A,MAP4K4,CIRBP,E2F3,ATP6V0A1,MEF2D,DNAJA1,TANC1,RAB1A,TAZ,FKBP3,DDX17,KIF2A,TAF2,PPP2CA,CDC16,LSM6,CORO1C,HIPK2,RNF38,FUS,PDXK,PPP5C,GEN1,ZBTB11,USP13,SRSF6,SESTD1,SIKE1,UBE4A,IP6K2,IL21R,ETS1,IFT27,SLC25A43,NEIL2,PPP1R3B,FBXO3,RPA2,ERH,PDCD10,CLIC4,ITGB8,SUV39H2,HUWE1,PPP1R8,ARF5,ARHGEF1,GEMIN6,UBE3B,GTF2H2,FBXL19,IMPA2,LDHB,PDPK1,STAU1,PPP3CA,TK1,TNFAIP3,DDX24,POLK,LDHA,MTMR12,RAB3IP,DDX39A,TTC33,PICALM,RPA1,MAGT1,POLE,CCDC6,WNT5B,PITX1,MAPK6,FAM3C,PML,AEN,HMGB2,RGL1,CD81,YWHAH,IGBP1,FAF1,ANAPC4,COX15,DDX47,WDR13,TRIM11,PPP1R15B,FAM129A,YTHDC2,SNX15,CSNK2A1,SEC16A,GIT2,BIRC2,FANCL,ABL2,RAB8A,PCNA,NUP210,NT5DC1,IL6ST,PIK3R2,XRCC2,ETV6,MYBL1,ASB6,PTPRK,VPS13B,PLK1,SP3,PTPN18,SEPT9,RBX1,APH1A,SNRPB,RAD51AP1,TLK1,GMFB,LNX2,CDC6,LRP5,UBE2V1,UTP3,BRCA1,RAB5B,USP21,RHEB,TRIM4,FBXO28,CHD3,E2F4,SOCS4,BCL7C,ADAM9,KPNA2,ACTB,DVL1,NUDT11,POT1,NUMB,FUBP1,DNAJB2,NKD2,LAMTOR3,RACGAP1,COX4I1,ADCK5,CDK13,RAB6A,DNAJB1,PPP3CB,B4GALT4,ARID1B,RAPGEF6,RB1,NUS1,VMP1,KIF13B,MBD2,XPA,RBM3,AFF1,MAML1,PREB,CYTH1,ABHD2,TRAPPC9,NSDHL,ACSL3,LDB1,KRAS,EIF2AK1,MAP4K3,UBE4B,ICAM2,APPL1,IRF5,RXRB,SDHB,MBIP,PCM1,CDC27,SYNCRIP,PALB2,COX7A2L,PRPS2,ZDHHC7,RUVBL2,CCNB2,USP7,SART1,TRAF7,SUCLG1,ARID2,FOXM1,XAB2,SUMO2,LAGE3,PCBP1,LYN,DUSP22,BCAP31,RAD23A,RPL11,VAV1,CSDE1,MRPL50,PDK2,PSMA6,MDM2,WDR44,PIN1,PDCD2,CORO1A,MINPP1,STRAP,SAP30L,SPSB3,DVL2,SNX25,KDM3B,ARHGAP17,CLCN3,BIRC3,BTG2,RAB7A,PPIE,CYP20A1,DNAJC9,NUP155,DCLRE1C,CHMP2B,ARL5B,EIF3H,USP36,SRSF1,DNAJC10,DHX16,PLEKHG4B,CLK3,RBL1,SCAP,STK38,MAFK,FASTK,UHRF2,DNAJC17,AP1S1,XRCC3,NCOA1,USP53,SMAD4,RAD51D,INTS2,BCL2L12,MCM10,GOLIM4,CDT1,ARID5A,TMX3,SMC6,NKRF,HMGN3,ARF1,CSNK1A1,SCYL2,DNAJB9,TFRC,FZD6,PTPN2,HERC3,IRF4,CTSS,ABCD1,SS18L1,DDX31,ORC3,CAMK2G,RNF5,CNTN5,RHOA,HMGN5,SNX2,TOP3A,ARHGEF12,PCGF1,DDX23,RAB18,TRIM26,KPNA4,PDCD6,FBXO41,ATP6V1D,BIRC5,TFE3,NEIL3,E2F1,PGRMC1,USP20,IMPDH1,PKD2,RBPJ,NR2F2,PGAM1,RPS6KC1,UBE2C,HIPK3,NUP188,MAX,PDCD6IP,ADAM10,CXXC1,TSC22D3,USP39,CUL1,CCNB1,IKBIP,UBE2I,PARK7,ZNF428,RAB4A,SUCLG2,CDC25B,PLCL2,TFG,SMARCE1,DNMT1,CDC5L,ORAI2,KLF10,AKT2,PBK,NOL8,GNG7,MKI67,DDX20,AURKB,USP22,CCNF,CBFB,RFC2,SLC25A5,RAB2B,EIF3A,DOT1L,ZMYM3,MAP3K4,ANKRD10,HHEX,WAS,TMED10,WDR4,ITGB1,PTPN7,PTPDC1,TRAF5,ZMAT3,HDAC2,PTOV1,DDX58,RECQL,COX5B,DNAJC5,EWSR1,CHTF18,GSPT2,C16orf87,PRKAA1,VAV2,RRM1,KIF23,CYCS,NOTCH2,PSEN1,METTL3,JMY,SPAG5,CFLAR,FKBP1A,RPN1,RNF121,MEX3C,SNX18,HDAC7,ATIC,PPP4R1,MSH2,DAPK1,FBXL7,CYC1,PIKFYVE,RNF135,GNAI2,ANKHD1,EEF1D,TERF2,SOCS5,PHF10,DDX28,PIGT,PRIM2,MFNG,PIP4K2C,ARID1A,PLEC,RIT1,KDM3A,MAP2K2,MTR,PHF6,AKAP1,FAS,PI4K2A,XRCC5,HMGN2,ADSS,CAT,DERL1,PFDN5,GOLGA2,TMEM54,ZFP92,RBMX,ACLY,PIAS2,USP32,PPP3R1,VCPIP1,CABIN1,GPI,YY1,MAP3K5,RNF14,CDK2,NRBP1,CDKN2A,ZC3HAV1,TP53RK,DNMT3A,REPS2,RAB11B,TRIP10,RAF1,SUZ12,RPS6KA1,SF3B1,MAGED1,RAC1,BCL2L1,SDHA,GNB2,EPM2A,PHC2,CRKL,TERF2IP,CCNA2,ZNF75D,SHC1,KDM2A,RALB,SIAH1,LPIN2,SOCS6,CDKN1B,TNPO2,TP53BP2,RBM12B,CDK12,NAA35,SAP30,CCT2,BRD4,MAPRE2,RFC3,HMGN4,ERF,NARF,CUL3,ABHD11,PKMYT1,CDC23,ASB13,POLG2,ERC1,EML4,TRIM28,DHX57,NSA2,RAD51C,HSPA4,PPP2R5A,JAK1,ACYP1,SAFB,STAT1,SEL1L,FTSJ1,H2AFX,NCLN,TRIM32,PDCD11,XRCC4,PRPF4B,ADAM23,RHEBL1,POLQ,OTUD5,NCOR2,MECP2,TCF3,CBLL1,BLM,POFUT1,HMG20A,FOXO3,RAB11A,HLA-A,MAD2L2,JAKMIP1,EBP,WWP2,PIP5K1C,PTEN,AHSA1,AXIN2,PRC1,PTPN11,COPS7B,UBE2M,NCOA2,MSH6,SMC4,JMJD4,LONRF3,NET1,NEK7,RABIF,ADSL,FBXO9,ANAPC2,BMS1,KIF11,MARK2,TSR2,FADD,CBX3,PLD3,FBXO21,GNA12,PFDN4,MFAP1,TFDP1,KHSRP,PPP1R11,DDX5,DUSP11,BRWD3,TAF6,ESPL1,DDB1,GPR89B,IPO4,FAM83G,DEF6,POLA2,RORB,PIGM,IER2,UBE2E2,GPR132,ST13,NF1,PTP4A3,UBE2Q1,TAF6L,AGFG1,SIRT2,KIF2C,FKBP2,USP48,UBQLN2,BECN1,MAPK14,RNF103,SF3B2,MBD4,DST,RAP1A,CDC42,EIF4A3,THADA,JAZF1,RAB35,PPP1R12C,RPF2,KIF22,RP2,NFU1,TCEA1,OGG1,ARID4A,TRIM14,CARM1,SRPK2,COPS8,TRIM8,NCK1,VHL,RRM2,WDR82,PITPNB,KMT2C,SOX4,STK17B,CHAF1A,CXXC4,GEMIN5,UEVLD,U2SURP,PPM1G,PQBP1,CAB39,STK11,CLU,CHEK2,COPS6,MRPL13,DCAF5,UBE2D3,PIGN,PPP1R2,PPP1R12A,UFC1,NACA,CIB1,PCSK7,MED13L,THRAP3,RGS2,XPO7,NUP205,ZNF449,BCL2,KNTC1,UBE3C,ZRANB1,MCPH1,N4BP2,CSNK1G3,ALDH9A1,ZNF189,SUGP2,OXR1,DAPK3,ARHGAP15,EVC2,MASTL,UAP1,KLHL15,SIAH2,PITPNA,YWHAZ,NUP62,RBBP4,TOB1,SMARCD1,MBD1,TCF12,WASF2,PRKAB1,SNX27,ASH1L,MDH2,PMS2,SMARCA4,PLAGL2,ORC1,TWF2,CHD1,MXD1,USP5,ANKRD28,SAP130,SAR1A,NVL,AKAP8,PPP6C,CS,APOOL,CHTOP,FAM3A,SCYL3,ABI1,DNAL4,EBAG9,MOSPD1,RLIM,POU2AF1,RNF25,PCGF6,METTL2A,ATXN1,GLO1,OGDH,BICD2,FANCE,PDHX,RAD54B,DAP3,TAB2,STAT6,HPS5,TULP3,CANT1,FKBP5,SCARB1,GAS2,USP11,SMURF1,MAPK1,PPP2R2D,CBX4,DNAJC2,CDS2,MAGEH1,SH2D3A,CASP6,RAE1,EYA1,SCYL1,NUP54,DBF4,CHIC2,MXD4,PIP4K2A,RGS1,MAN1A1,FBXO5,FGFR3,CTNNBL1,SEC24C,TANK,ARHGEF2,STAT3,FRMD8,MYO5A,AMPD2,CSNK1G2,ADAM17,HMGN1,SCFD2,PRMT2,TFEB,MAPK3,MTMR3,COX8A,KBTBD7,SRSF3,ZMIZ1,IDH3B,TERF1,HRAS,RAB3IL1 |
| 3.636e-15 | -33.25 | establishment of localization | biological process | GO:0051234 | 4314 | 818 | 17256 | 2622 |
CCDC93,TMED7,RAB14,TSC2,ADD1,ABCC10,HEXB,TGOLN2,SYNRG,CMTM6,FBXO22,MIS12,RPL23A,CDK5,NAPG,PSMD1,RABGAP1L,SRSF4,ATP13A3,AP1M1,DNM2,UPRT,NUP153,KCNAB2,BAK1,PGAP2,RHOBTB3,TMEM115,NRAS,KIF15,MCL1,PPFIA3,NUTF2,ICMT,RAB22A,SLC50A1,ARF4,PLEKHF2,STOML2,MID1IP1,SMAD2,RPS27A,LIMK1,MYO18A,COX5A,VIPAS39,ATP6V0C,TFDP2,LONP2,AAAS,ANXA11,SLC25A33,NXT2,GGA1,SEC61G,CCZ1,DHX9,RAB23,SLC4A2,TMED3,PSMD9,COPB2,ATG4A,TMEM179B,GNS,CD59,EIF2S2,SLC38A5,RIMS3,FBXO7,TNPO3,GEMIN4,CPSF4,MVP,NUP85,PPP6R1,SRSF11,NAGPA,CYFIP1,TIMM8B,MAPKAPK3,ERO1A,RPS10,SSR2,SRSF5,MTX1,SFXN5,ABCF1,RHOB,CYB5A,MAGED2,SCARB2,OSBPL11,KPNA1,NDE1,SGF29,SNX14,NUP58,ALS2,RHOG,EXOC3,ANKRD27,ABCA3,SARNP,ACTR3,ANK3,VTI1A,C5orf30,STARD7,MON1B,MYH9,TBC1D13,NUF2,NIPA2,NIT2,SLC35B2,STAM,CPNE3,REPS1,APP,CLUAP1,RAB21,AHCTF1,ATP2A2,SH3BP1,TBC1D22A,TBC1D14,NUP107,CLCN6,MICU2,ATF2,ZC3H3,DCTN1,ATP6V1G1,SNX8,ENPP4,CPNE1,SEC61B,PSRC1,GOPC,WBP2,RPL38,POLR2D,RNPS1,ATP6V0A1,HTATIP2,NUSAP1,DNAJA1,RAB1A,KIF2A,ALDH3B1,PEX5,SEC61A1,VPS26B,CORO1C,RPLP1,PDXK,SNRPG,PITRM1,LRP8,TUBB,RPS2,ANXA6,SRSF6,HABP4,FLOT1,TRAK1,BTN3A1,JMJD6,ATP5F1B,IP6K2,IFT27,SLC25A43,WRB,SAPCD2,PSMD2,PDCD10,ADD3,CLIC4,HUWE1,ARF5,ANXA5,GEMIN6,GTF2H2,TPCN1,S100A6,SPTAN1,PPP3CA,TNFAIP3,GUK1,MRS2,HEBP2,MTMR12,RAB3IP,DDX39A,PICALM,SLC19A1,KIF18A,MAGT1,FAM3C,LRPPRC,PML,LY75,SLC25A19,SSNA1,PSAP,CD81,USF2,YWHAH,SNAPIN,COX15,THOC1,SNX15,RBM8A,CDC42SE2,SEC16A,RUFY1,GIT2,KCMF1,SSR1,RAB8A,NUP210,TIMM23,PIK3R2,SLC44A1,TXLNA,ZFYVE27,ABCC5,VPS13B,CDC37,PLK1,SNRPB,TLK1,CYSTM1,EZR,LRP5,ESYT1,STX16,RAB5B,LSG1,OPTN,NECAP2,TRAM2,TBC1D17,TIMM13,AGPAT2,GRIPAP1,ARRDC1,KPNA2,ACTB,PIEZO1,DVL1,CLN3,POT1,C2CD5,GEMIN7,PHB2,CENPF,NKD2,LAMTOR3,KLC1,ASAH1,COX4I1,RACGAP1,CDK13,RAB6A,NCKAP1,PPP3CB,RINL,VMP1,KIF13B,ARL6IP1,SLC27A4,GLE1,LRSAM1,PREB,ABCC1,CYTH1,TRAPPC9,ACSL3,EIF2AK1,ARPC1A,ARMC8,APPL1,NPIPA1,ZDHHC3,NMT2,BBS12,PSMC4,RPL36,GOLGA4,PCM1,SNAP23,COX7A2L,ZDHHC7,SIL1,RUVBL2,ATP5F1A,UNC13C,NIPA1,RPLP2,DYNLL1,SLC2A1,COPE,ZFYVE21,ATP6V1B2,LYN,BCAP31,RPAIN,RPL11,VAV1,ATP6V0B,PSMA6,MDM2,BRPF3,BCAP29,CORO1A,LMAN1,AHCYL1,GM2A,SNX25,SLC39A9,PPIF,ARHGAP17,RPL29,CLCN3,TIMP2,RPL35,PPT1,PSMA8,RAB7A,PPIE,SLC26A6,MTMR6,NUP155,CHMP2B,VDAC1,RHBDF2,TMEM201,RPSA,SRSF1,ATP1A1,PSMD3,TIMM17A,TOMM6,CEP55,DNAJC17,AP1S1,CHMP4B,NCOA1,SLC22A23,LTA4H,AP2S1,CHID1,SLC25A39,PARD3,SLC30A9,SMAP1,CDC40,PDAP1,CDT1,CDCA8,TMX3,ARFIP2,ARF1,SLC12A9,GGA2,CSNK1A1,AP3S1,SCYL2,TFRC,CTSS,SLC1A4,SLC35B4,ABCD1,CAMK2G,RNF5,RBM15B,MLEC,RHOA,SNX2,PNPLA8,RHOT2,NEU1,RAB18,CACNB1,SEC23IP,KPNA4,PDCD6,ATP6V1D,GOLGA7,SNAP29,E2F1,PGRMC1,IMPDH1,USP20,PKD2,RBPJ,SPCS3,PGAM1,CHMP7,NUP188,PDCD6IP,ADAM10,TSC22D3,TMEM109,AP3M2,TAP1,GYG1,NHLRC3,CCNB1,SLC20A1,PARK7,RIC1,SLC25A37,KIFC1,PA2G4,SNUPN,ASAP2,CYB5RL,RAB4A,AP2B1,SLC26A2,MARCH2,TFG,SEH1L,SRSF10,SRP72,ORAI2,USO1,OSBP2,ATG9A,AKT2,ARHGAP45,DDX20,SLC17A5,MCFD2,SLC25A5,RAB2B,CLNS1A,IWS1,HHEX,WAS,TMED10,PSMD8,RPS14,MAP4,EIF2D,ITGB1,SARAF,BTF3,RRS1,ARRB2,RTN3,ZMAT3,NMD3,SVIP,HSPH1,COX5B,DNAJC5,GMFG,ANKH,VAV2,ACAP1,B4GALT1,KIF23,NDUFA4,MAN2B1,SLC35B1,PSEN1,TMEM165,VPS25,COPG2,NDUFS7,NPLOC4,SPAG5,FKBP1A,SLC31A1,ARPC5,SNX18,LRRC8D,SLC25A51,ATP6V0A2,OSTF1,CYC1,PIKFYVE,LPCAT1,SYTL3,APOL1,TMED2,TERF2,EIF5A,FTL,GCC2,SIGMAR1,WDR1,EMB,C1orf35,RPS24,ARID1A,ADRB2,CAPZA2,PKM,CYFIP2,FXR1,PTTG1IP,TOMM40,GOSR1,CCT8,PSMB3,XRCC5,PI4K2A,DERL1,CAT,SEC31A,EPRS,SLCO4A1,GOLGA2,NSF,CSNK1G1,ERGIC3,ACLY,ARAP1,APPL2,PPP3R1,FAM83D,GPI,PPP6R3,CDK2,NRBP1,NDC1,SYS1,CKLF,RAB11B,TRIP10,RAF1,RAC1,GPR89A,SLC39A13,OLA1,BCL2L1,SLC25A44,AP1B1,CD320,MOAP1,APLP2,TNPO2,CDKN1B,BRI3,TAP2,TP53BP2,TMBIM1,CCT2,ATP13A1,CUL3,VDAC2,SLBP,LRRC8A,CDC23,AP4E1,PSMB9,ERC1,SERP1,HSPA4,CHMP4A,DSN1,DDOST,RAB24,SEL1L,EYA2,DYNC1LI2,CSNK1D,SCAMP3,SLC41A1,MECP2,MANBA,SLC25A12,SPDL1,RAB11A,HEATR5B,PIP5K1C,WWP2,JAKMIP1,SLC25A36,EBP,RPL17,RPL19,SLC38A10,UPF2,TAGLN2,CNN2,CREB1,MTX2,IFT46,NCOA2,DENND1B,DENND4C,RPL8,RABIF,KCNQ1,RHOT1,KIF11,RPL27A,MACF1,SMAP2,YIF1A,HGS,RPL32,LTBP4,ATP5MC3,SLC38A7,CCZ1B,STX18,TFDP1,KHSRP,ASNA1,WDR91,ESPL1,GPR89B,IPO4,VPS29,ESYT2,POLA2,ADA2,MTX3,COPA,NF1,ALKBH5,UBE2Q1,ABCB10,SLC29A1,KIF2C,AGFG1,SNRPD3,MAPK14,BECN1,ATP5PF,CUTC,PCYOX1L,DST,RAP1A,CDC42,GOT2,EIF4A3,AP3S2,RAB35,ATG3,DPYSL2,SRI,KIF22,RP2,SLC35C2,CNNM3,CARMIL1,TIMM50,FYTTD1,LARS,NCK1,SLC16A7,SLC25A22,PITPNB,MPC1,RPL37,GEMIN5,HSPB11,EIF4ENIF1,UEVLD,TIMM29,MIA2,CAB39,CLU,VPS4A,ROCK1,RPS26,PSMC1,ATP6V0E1,CAPN1,STARD3NL,SLC12A7,TBC1D12,RPS15,TM9SF4,GORASP1,EPN1,RPL15,XPO7,RHBDD1,NUP205,CHKA,BANF1,CAPZA1,ORAI1,KIFAP3,BCL2,GLTP,MCPH1,SLC12A2,ATP6V0D1,CSNK1G3,KDELR1,ATP5IF1,CREG1,ERLIN1,RPL6,PSMA1,SYVN1,TMEM241,CAND1,TSC1,CDCA5,EXOC4,SLC16A1,NUP62,YWHAZ,CTSA,PITPNA,EHD4,TMEM14A,APOL2,WASF2,SNX27,CHMP2A,CORO7,TOMM20,CHERP,CLCC1,HNRNPA2B1,ANKRD28,ANKLE1,SAR1A,KIF14,AKAP8,PPP6C,PARL,SCAMP4,CYB5R1,APOOL,CLTB,CHTOP,PDIA6,F2R,ABI1,CHP1,NXT1,PSMB7,ATXN1,WIPF1,BICD2,ERBIN,TOLLIP,PEF1,RPS9,SURF4,VPS26C,ARNTL,CANT1,ANP32E,SCARB1,SMURF1,MAPK1,ABCA1,TMEM33,MIF,KIF3B,GOLPH3L,RAE1,SCYL1,DCTN2,SRGN,NUP54,VPS45,TIMM21,CHIC2,MFSD10,XPR1,FERMT3,KIF5B,GRK2,KLHL20,SEC24C,RRBP1,NABP2,ZDHHC13,H2AFY,ANP32A,ARHGEF2,YIF1B,LDLRAD3,STAT3,SLC35A1,MICAL3,MYO5A,SLC25A1,NIPAL3,TGFB1,ZDHHC18,CSNK1G2,FAM49B,NASP,ATP2C1,SCFD2,COG1,WDR81,ATP5MF,SYMPK,MAPK3,HSPA1B,MFN2,LEMD2,UPF1,ELMO1,OSBPL8,COX8A,SRSF3,ATP6V1C1,HRAS,TERF1,RAB3IL1 |
| 3.780e-15 | -33.21 | GO_PROTEIN_COMPLEX_SUBUNIT_ORGANIZATION | MSigDB lists | GO_PROTEIN_COMPLEX_SUBUNIT_ORGANIZATION | 1437 | 324 | 17377 | 2626 |
MAX,ADD1,NDUFB6,MRPS15,XIAP,OAT,CCNB1,MIS12,KIFC1,NAPG,NEK6,DNAAF2,AP2B1,NUP153,TFG,SMARCE1,SEH1L,PLK3,USO1,MRPL43,AURKB,SMC2,MCFD2,MCM2,FOXRED1,STOML2,AHNAK,WAS,MID1IP1,SMAD2,BRD2,KIF18B,TMED10,PSMD8,AXIN1,MAP4,MRPL27,ITGB1,OGT,SMAD1,SLC25A33,NDUFV2,MRPL9,DHPS,PRKAA1,GSPT2,KCTD17,RRM1,KIF23,HAUS4,PSMD9,ITGB5,HAUS2,CDC73,NDUFS7,JMY,SPAG5,NDUFS4,TFAP4,CD59,FKBP1A,PDXP,SMC3,ARPC5,ATP6V0A2,MRPL40,MRPL21,PPP6R1,TMED2,TSPYL4,MYBL2,MRPL16,ARID1A,ADRB2,CAPZA2,EIF4H,CCT8,FAS,DERL1,SEC31A,CAT,EPRS,GOLGA2,NSF,RBMX,ARAP1,CABIN1,PPP6R3,NDE1,RUFY3,MRPL3,ZNF207,REPS2,RAF1,ACTR3,RAC1,TPX2,MYH9,POMP,STMN1,DECR1,AHCTF1,NUP107,MRPS27,SEPT11,TNPO2,CEP63,CFL1,CCT2,GOPC,CUL3,ATP6V0A1,NDUFA7,RAB1A,TAZ,TRIM28,SUPT16H,KIF2A,HSPA4,CHMP4A,PEX5,MRPL55,H2AFX,PPP5C,CSNK1D,TUBB,POLQ,NDUFS1,ANXA6,FLOT1,BLM,RAB11A,MAD2L2,PDCD10,NDUFA2,NDUFB4,CENPJ,PRC1,AXIN2,MRPL54,ANXA5,NAP1L4,NDUFA3,SMC4,TK1,TNFAIP3,NEK7,TMEM126B,MRPS10,ADSL,KIF11,PICALM,FADD,SH3GLB1,KEAP1,KIF18A,PML,HMGB2,NDUFS5,WDR62,ESPL1,IPO4,COX15,ST13,NF1,UBN1,UQCR10,KIF2C,AGFG1,SIRT2,SEC16A,CUTC,MRPL19,BIRC2,ATPAF1,PRNP,DLG5,CDC42,ZNHIT6,NDUFB9,MRPL32,SEPT9,NCK1,MRPL12,EZR,LNX2,RRM2,PSMG1,LRP5,ANLN,ASF1B,CHAF1A,DPYSL3,GEMIN5,PAF1,TRIM4,CHD3,CAB39,STK11,DVL1,VPS4A,CLU,CHEK2,MRPL13,NAA60,HJURP,GORASP1,CENPF,CIB1,CTCF,RACGAP1,NUP205,VASP,SSBP3,MBD2,CAPZA1,KIFAP3,BCL2,KNTC1,MRPL48,ALDH18A1,PREB,HP1BP3,TRAPPC9,SEPT7,ARPC1A,BBS12,CAND1,HAUS8,TSC1,NAP1L1,PCM1,SNAP23,NUP62,RBBP4,EHD4,PDSS2,SMARCD1,KCTD7,NDUFA5,PRKAB1,CHMP2A,CYLD,TOMM20,CORO7,ARID2,NDUFAF2,MRPL39,SLC2A1,SMARCA4,ANKRD28,MRPL50,OIP5,MDM2,KIF14,MRPL34,PPP6C,CORO1A,LMAN1,ABI1,DVL2,BIRC3,TUBGCP5,FRAT2,WIPF1,CHMP2B,NDUFB1,MRPS14,MRPL2,DAP3,IDE,CHCHD1,NDUFA11,ANP32E,CHMP4B,H3F3A,AP2S1,SMAD4,PARD3,TMEM33,MIF,KIF3B,MRPL42,SHPRH,DCTN2,NUP54,MRPS26,PAWR,ARF1,CSNK1A1,TUBGCP2,GFM2,FERMT3,FBXO5,STARD9,NDUFV1,SEC24C,ARHGEF2,H2AFY,NDUFS8,CENPM,TTC17,MRPL11,CAMK2G,MICAL3,TGFB1,PPP1R9B,RHOA,NASP,SNX2,TIMMDC1,ASPM,MEN1,MAPK3,SEC23IP,BIRC5,SNAP29,ACAT1,CENPT,PLOD3,CHMP7,UBE2C,HRAS,TERF1 |
| 4.040e-15 | -33.14 | GO_REGULATION_OF_MITOTIC_CELL_CYCLE | MSigDB lists | GO_REGULATION_OF_MITOTIC_CELL_CYCLE | 453 | 133 | 17377 | 2626 |
HECA,UBE2E2,PDCD6IP,GPR132,CUL1,CSNK2A1,SIRT2,CCNB1,BECN1,FANCI,PCNA,PSMD1,NEK6,CDC42,CDC25B,ECD,CARM1,PLK3,PLK1,AATF,LRP5,CDC6,USP22,SOX4,ANLN,RPS27A,PSMD8,E2F4,ZNF268,CHEK2,TFDP2,PSMC1,CLSPN,GORASP1,PHB2,CENPF,TOP2B,CDK13,PSMD9,CDC73,CNOT3,RB1,PDXP,FBXO7,MSH2,BCL2,KNTC1,PSMA1,PSMB3,RBM38,DAPK3,PSMC4,GOLGA2,CDC27,DUSP3,CDCA5,CNOT6,ZNF830,CDK2,CDKN2A,ZNF207,CHMP2A,CYLD,PTTG1,TPX2,SMARCA4,BCL2L1,APP,PSMA6,CCNA2,MDM2,KIF14,PIN1,CDKN1B,ANAPC7,ATF2,CTDSP2,BRD4,TIMP2,PSRC1,CDC123,PSMA8,BTG2,CUL3,PSMB7,NUSAP1,PKMYT1,CHMP2B,RAB1A,CDC23,PSMB9,RAD51C,CDC16,NSMCE2,PSMD3,XRCC3,CHMP4B,GEN1,TCF3,BLM,RAB11A,MAD2L2,FBXO5,RPA2,RFWD3,PSMD2,PTEN,CENPJ,PTPN11,BRD7,H2AFY,GTSE1,CNOT6L,TGFB1,PPP1R9B,ADAM17,PRKDC,NEK7,ANAPC2,PRMT2,KIF11,BORA,BIRC5,TFDP1,E2F1,PML,PKD2,UBE2C,TERF1,ESPL1,HRAS,DDB1,ANAPC4 |
| 4.091e-15 | -33.13 | RPL10 (ribosomal protein L10) | protein interactions | 6134 | 339 | 113 | 17029 | 2761 |
BCCIP,DDX47,CYLD,NOP2,RPLP2,SF3B1,YTHDF3,EBNA1BP2,CNTROB,SND1,BRIX1,LYN,CHD1,MEAF6,EPM2A,RPL11,RPL23A,DECR1,PA2G4,CMSS1,EIF4A3,NVL,MRPS27,CRY2,KIF22,TARDBP,FTSJ3,SRP72,RPL29,RFC3,RPL35,AATF,NSUN2,RPL38,CUL3,MKI67,RIOX2,AURKB,BRCA1,MCM2,RFC2,LSG1,EIF3G,RPS9,RPSA,DHX57,CENPU,USP36,EIF3A,SUPT16H,UBTF,CHD3,RPS27A,NIP7,RPS14,RPLP1,BAZ1B,XRCC3,BTF3,RPS26,ZNF598,HDAC2,RPS15,RPS2,RRP15,PDAP1,NACA,DHX9,RPL15,TOP2B,PDCD7,PNO1,LYAR,RPL17,BANF1,ZNF746,RTCB,RPL19,RBM3,MRPL48,FBL,MRM3,PABPC1,HNRNPM,HP1BP3,EIF3L,STAU1,FOCAD,DDX24,DHX29,ZMYND11,TEX10,ABCF2,RPS10,RPL6,GTPBP4,RPL8,ILF3,USP10,RPS24,MPG,RPL27A,PHF6,RPL36,CAND1,LEMD2,SYNCRIP,RPL32,QARS,MAPK6,TBPL1,DDX5,IFI16 |
| 4.117e-15 | -33.12 | STEIN_ESRRA_TARGETS | MSigDB lists | STEIN_ESRRA_TARGETS | 486 | 140 | 17377 | 2626 |
TMEM184B,DCAF15,GNPDA1,NANS,MBD4,GOT2,THAP4,DBNDD1,RAB35,MECR,NFU1,ASB6,TRIM14,ARID4A,TIMM50,SRPK2,TRIM8,WDHD1,SMC2,PRPSAP1,TRAM2,QRSL1,MLYCD,COX5A,TRIM52,ZNF45,PFKP,COX5B,MUT,ZNF768,HLA-E,TRIO,CYCS,RAPGEF6,NDUFS7,CFLAR,NDUFS4,SLC31A1,AFF1,PCYT2,NAGPA,CYTH1,SIGMAR1,NQO2,SEPT8,DCTD,RBM38,AKAP1,SDHB,NAP1L1,ETS2,QARS,PRPS2,SLC16A1,MDH1,GPI,RNF14,RNF139,NUDT3,EGLN1,MMACHC,IMMT,SUCLG1,UGP2,IVNS1ABP,MDH2,RPS6KA1,TMX4,STARD7,UCK2,TWF2,DUSP22,SDHA,ANKRD28,DECR1,RAB21,ZNF302,TNFAIP8,CS,MRPL34,INTS12,AHCYL1,RBM12B,GM2A,PPIF,KIAA0040,IDH3A,CRNKL1,VDAC2,HTATIP2,OGDH,CDC23,PDHX,TMEM184C,EIF3K,CHCHD3,MRPL2,ACYP1,TIMM17A,PPP2R2D,KIF3B,NDUFS1,ANXA6,B4GALT5,LETMD1,SLC25A12,ATG2B,JMJD6,GMCL1,SIKE1,MXD4,IFT27,EBP,FGFR3,GSTK1,PDCD10,NDUFV1,NDUFS8,MRPL11,MTX2,MSH6,RNF5,IMPA2,CSNK1G2,TACC1,RFXANK,RABIF,FAM50B,PCGF1,TTC33,MFN2,NUCB1,SLC38A7,TFE3,STX18,ACAT1,ACADM,IDH3B,NR2F2,TERF1 |
| 4.283e-15 | -33.08 | FUS (FUS RNA binding protein) | protein interactions | 2521 | 335 | 112 | 17029 | 2761 |
MAX,CYLD,SARNP,ST13,SUZ12,MDH2,CUL1,GLUD1,OAT,C2orf49,UBE2I,SAFB2,RPL11,PA2G4,PCNA,GOT2,PIK3R2,SRSF4,TXLNA,RPN2,KIF22,TARDBP,PCBP2,CFL1,TIMM50,SRSF10,CDC5L,CCT2,LARS,PSRC1,RAB7A,PSMB7,CUL3,HNRNPF,BRCA1,MEF2D,MCM2,SLC25A5,MBD3,RPS9,DHX15,MAT2A,RAD54B,DDX17,DNAJC10,DGCR8,RPS14,RPLP1,ATXN2L,KPNA2,ACTB,FUS,COPS6,H3F3A,GEN1,ABCA1,PFKP,TUBB,DDX42,HIVEP3,EWSR1,GOLIM4,TKT,NKD2,ADCK5,ATP5F1B,PM20D2,NPLOC4,LMNA,RPA2,KLHL5,RTCB,NAA50,ANXA5,YBX1,AHCY,UPF2,LDHB,PSPC1,NSDHL,ABCF2,TUFM,LDHA,ILF3,PKM,EIF4H,CCT8,PICALM,MATR3,SF3A2,TARS,PRDX1,POLR2A,RPA1,CAND1,GNAS,NAP1L1,PCM1,UPF1,SYNCRIP,RBMX,TBPL1,ACAT1,MDH1,YWHAZ,DDX5,GPI,ATP5F1A,RBBP4,CDK2,USF2,HNRNPDL |
| 4.579e-15 | -33.02 | MODULE_252 | MSigDB lists | MODULE_252 | 232 | 83 | 17377 | 2626 |
H2AFZ,FOXM1,PTTG1,CSNK2A1,KIF2C,ORC1,CCNB1,STMN1,MAPK14,RAD23A,CDKN2C,APLP2,PCNA,ASAP2,CCNA2,POP7,NUP107,TRA2B,NUP153,DNMT1,SRSF10,SRPK2,CDC5L,SAP30,PLK1,RFC3,HMGN4,E2F3,HNRNPF,POLR2D,SLBP,WDHD1,SMC2,SOX4,CHAF1A,SRSF1,PRIM1,RAD51C,HNRNPR,STK38,STAT1,H2AFX,XRCC3,LRP8,COIL,CBX4,RAD51D,ZNF146,HDAC2,SSRP1,PRPF4B,EWSR1,CENPF,DHX9,CTCF,KIF23,RPA2,PSMD2,MSH2,YBX1,KNTC1,NASP,PRIM2,PRKDC,MYBL2,ILF3,PSMC4,RPA1,DDX23,XRCC5,NAP1L1,BIRC5,DCK,TFDP1,E2F1,KHSRP,HMGB2,DDX5,RBBP4,TAF6,CCNB2,CDKN2A,ADNP2 |
| 5.338e-15 | -32.86 | GSE15930_NAIVE_VS_48H_IN_VITRO_STIM_CD8_TCELL_DN | MSigDB lists | GSE15930_NAIVE_VS_48H_IN_VITRO_STIM_CD8_TCELL_DN | 188 | 72 | 17377 | 2626 |
CCNC,NANS,STMN1,PABPC4,FARSA,PSMD1,KIF22,TARDBP,PDIA6,LRRC59,ARL5A,PDCL3,ELOF1,CDC123,PSMB7,MRPL12,RNPS1,RRM2,HTATIP2,PSMG1,CDC6,SMC2,NUTF2,CCNF,RAB1A,STOML2,HSPA4,TIMM13,CDC16,MRPL27,H2AFX,OGT,KPNA2,MRPL13,PSMC1,MCM10,PHF23,PDAP1,RRM1,DNAJB1,REEP5,DTL,GART,EXOSC7,BANF1,PRC1,TNPO3,AHCY,MRPL11,CPSF4,UBE2M,TIMM8B,NASP,HMGN5,ASPM,SSR2,PSMA1,KIF11,ABCF1,PRDX1,MTHFD2,PRDX3,DBI,TFDP1,PGRMC1,ZRANB2,SSNA1,HMGB2,NUP62,RUVBL2,ANAPC4,S100PBP |
| 5.338e-15 | -32.86 | GSE22886_UNSTIM_VS_STIM_MEMORY_TCELL_DN | MSigDB lists | GSE22886_UNSTIM_VS_STIM_MEMORY_TCELL_DN | 188 | 72 | 17377 | 2626 |
SRM,TCF12,H2AFZ,NOP2,MRPL39,C5orf30,UBE2Z,GLRX3,KIFC1,FANCL,ATP13A3,NUP107,BCAP29,TTC4,RNF19A,MOB1A,LRRC59,RYBP,CDC123,IDH3A,CPOX,VDAC2,HNRNPF,ICMT,RAB1A,ODC1,DHX15,MAT2A,CHAF1A,PRIM1,TAF2,ZNF282,HSPB11,DSN1,HNRNPR,COX5A,PRPF4,SNRPG,MRPL13,AP2S1,NXT2,RRP15,TRIP12,SRGN,CDK2AP2,CDT1,DBF4,DHX9,NCKAP1,SLC35B1,REEP5,BZW2,NUP205,FKBP1A,ATIC,NAA50,PTPN11,CTR9,CYC1,SMC4,TIMM8B,ELL2,ERLIN1,AMD1,ABCF2,THNSL1,SDHB,DERL1,PLAA,HMGB2,GPI,IPO4 |
| 5.351e-15 | -32.86 | PAXIP1 (PAX interacting protein 1) | protein interactions | 22976 | 262 | 94 | 17029 | 2761 |
NOP9,SKA3,NOP2,SUZ12,COPE,CSNK2A1,EBNA1BP2,KIF2C,SNRPD3,APP,KRR1,BABAM2,PSMA6,SRSF4,TRA2B,ANAPC7,TARDBP,TECR,STRAP,CDK12,PCBP2,SRSF10,CDC5L,MAPRE2,NXT1,ERF,MAP4K4,LACTB,CIRBP,WDHD1,WDR82,DNAJA1,SMC2,CDC23,KDM1B,KMT2C,RFC2,PRPSAP1,CENPU,EIF3H,SRSF1,STOML2,PPP2CA,SMAD2,CDC16,RPS27A,U2SURP,H2AFX,CLU,PDCD11,PKP4,PPP1R12A,PHB2,BABAM1,STRN4,THRAP3,BLM,WDR5,PAGR1,NCAPG,WDR48,KRI1,CCNK,LYAR,ERH,SMC3,EIF2S2,INTS7,PELO,CAPZA1,DCP1A,YBX1,MRM3,LUC7L2,LDHB,HP1BP3,MOB4,STAU1,WDR18,LDHA,BCLAF1,SRSF5,RPA1,DDX23,CDC27,RBM25,PML,PIAS2,KMT2B,SNRNP70,CCNB2,ANAPC4,GPATCH4,DDX52 |
| 6.265e-15 | -32.70 | MDM2 (MDM2 proto-oncogene) | protein interactions | 4193 | 462 | 141 | 17029 | 2761 |
IER2,UBE2E2,TSC22D3,XIAP,KIAA1551,CUL1,UBE2Z,CSNK2A1,SIRT2,SND1,UBE2I,RPL23A,ABL2,PA2G4,RAB8A,PCNA,PSMD1,CMSS1,SIVA1,NOC2L,SMARCE1,CCAR1,RYBP,PLK1,USO1,EXOSC6,AATF,PBXIP1,ARHGAP45,EHMT1,EZR,SREK1,ESYT1,SOX4,MAK16,TRIM4,UBTF,RPL37,RPS27A,RPS14,ACTB,CLU,CHEK2,ARRB2,TRAF5,RPS26,PSMC1,POT1,NUMB,DDX42,FUBP1,UBE2D3,PPIB,RPS15,RECQL,NACA,DHX9,RRM1,RPL15,DNAJB1,TTF1,YY1AP1,JMY,DTL,FKBP1A,RB1,EFTUD2,DAPK1,MYDGF,SRSF11,DCAF8,RPL6,USP10,EIF2AK1,UBE4B,ADRB2,PKM,RBM38,DAPK3,GNAS,KPNA1,RUVBL2,YY1,CDKN2A,USP7,KARS,TP53RK,SF3B1,SUZ12,SMARCA4,APP,RAD23A,RPL11,ZNF420,MDM2,IARS,ATP2A2,MTA1,RLIM,CDKN2AIP,UBQLN4,EID1,PSMA8,GORAB,OGDH,TRIM28,FKBP3,RAD54B,DDX17,HSPA4,JAK1,HIPK2,SMURF1,TUBB,CSNK1D,CWC25,CSNK1A1,FOXO3,TFRC,RFWD3,PSMD2,GRK2,UBE2M,RPL22L1,HNRNPM,S100A6,PPAN,HMGN1,RHOA,DDX24,USP42,ILF3,RFFL,ANAPC2,POLE,E2F1,PML,DDX5,PGAM1,IFI16,DDB1 |
| 6.273e-15 | -32.70 | GO_DNA_REPAIR | MSigDB lists | GO_DNA_REPAIR | 432 | 128 | 17377 | 2626 |
UBE2I,FANCI,MBD4,FANCL,PCNA,XRCC2,RAD23B,CRY2,KIF22,TCEA1,OGG1,CDC5L,COPS8,TDP1,ERCC1,RBX1,RAD51AP1,UBE2V1,BRCA1,RFC2,GINS4,CHAF1A,RAD18,TONSL,RPS27A,BAZ1B,CHEK2,COPS6,SSRP1,UBE2D3,RECQL,NSMCE4A,CLSPN,POLR2K,MUM1,CIB1,WDR48,NPLOC4,JMY,DTL,SMC3,XPA,MSH2,POLR2I,USP10,MPG,ISG15,XRCC5,PALB2,POLR2J,CDCA5,RUVBL2,YY1,ZNF830,CDK2,USP7,BCCIP,ATXN3,FOXM1,XAB2,PTTG1,CHD1L,SUMO2,RMI2,PMS2,INO80E,RPAIN,RAD23A,KDM2A,MTA1,UCHL5,AQR,RNASEH2A,PRPF19,RFC3,POLR2L,POLR2G,BTG2,PPIE,TAOK1,POLR2D,DCLRE1C,FANCE,POLG2,TRIM28,SUPT16H,RAD54B,RAD51C,NSMCE2,H2AFX,XRCC3,PPP5C,XRCC4,GEN1,EYA2,CSNK1D,RAD51D,POLQ,SLC30A9,TRIP12,EYA1,SHPRH,BABAM1,SMC6,BLM,RMI1,NEIL2,MAD2L2,WRNIP1,RPA2,RFWD3,HUWE1,COPS7B,GTF2H2,MSH6,HMGN1,POLK,PRKDC,TOP3A,PARP4,MEN1,POLR2A,RPA1,UPF1,POLE,NEIL3,HMGB2,DDB1 |
| 6.462e-15 | -32.67 | RPS8 (ribosomal protein S8) | protein interactions | 6202 | 287 | 100 | 17029 | 2761 |
NOP9,CYLD,NOP2,RPLP2,CHERP,SF3B1,CUL1,EBNA1BP2,NENF,RBM4,MRPL19,RPL11,RPL23A,SF3B2,KRR1,PSMD1,EIF4A3,MRPS27,MRPL34,HADHB,GPATCH1,RPF2,MRPL32,MRPL57,RPL35,AATF,MRPL43,RPL38,CUL3,BRCA1,MCM2,SLC25A5,MRPS14,RPS9,RPSA,NSA2,MRPL2,DAP3,DGCR8,RPS27A,PSMD8,RPS14,PSMD3,MRPL27,U2SURP,RPLP1,FUS,RRS1,ARRB2,MRPL13,SMURF1,PSMC1,RPS26,POT1,NIFK,RPS15,RPS2,MRPL9,MECP2,MRPS26,RPL15,RPA2,HUWE1,RPL17,RBM34,RPL19,MRPL40,FBL,MRPL11,MRPL21,PABPC1,HNRNPM,TERF2,HP1BP3,STAU1,EIF3L,RPS10,RPL6,UTP15,RPL8,ILF3,TUFM,RPS24,MRPL16,LLPH,RPL27A,RPA1,CAND1,RPL36,RPL32,CDK2,CD81,TERF1,PURA,MRPL3,ZC3HAV1,IPO4,GPATCH4,BYSL,ZBTB24 |
| 6.712e-15 | -32.63 | symbiont process | biological process | GO:0044403 | 725 | 189 | 17256 | 2622 |
NUP188,PDCD6IP,TSC2,THOC1,UBN1,KDM4A,YTHDC2,TAP1,CUL1,SND1,UBE2I,BECN1,SF3B2,RPL23A,USF1,NUP210,CDC42,IL6ST,ZNF639,SIVA1,AP1M1,AP2B1,NUP153,SEH1L,PCBP2,CARM1,RBX1,SLC25A5,EIF3A,RPL37,RPS27A,RPS14,EIF2D,ITGB1,ATP6V0C,KPNA2,VPS4A,COPS6,RPS26,RTN3,AAAS,DDX58,PPIB,RPS15,DHX9,RPL15,KLC1,CDK13,EIF2AK4,RAB6A,NCKAP1,ITGB5,NUP205,WDR48,MCTS1,CFLAR,TMEM250,TFAP4,RB1,SMC3,BANF1,MDFIC,CPSF4,LRSAM1,NUP85,MORC3,EIF3L,ZMYND11,RPL6,RPS10,RPS24,EIF4H,PSMB3,NMT2,ISG15,XRCC5,RPL36,DERL1,SCARB2,KPNA1,SYNCRIP,CCDC86,NUP62,MAP3K5,NUP58,USP7,WASF2,NDC1,CHMP2A,KARS,RPLP2,IVNS1ABP,DYNLL1,EIF3D,RAC1,MON1B,SMARCA4,BCL2L1,IRF3,AP1B1,LYN,PCBP1,CHD1,RPL11,RAD23A,CCNA2,MDM2,SHC1,SP100,NUP107,TAP2,TARDBP,MAVS,RBM15,ABI1,PDCL3,CFL1,RPL29,BRD4,RPL35,RAB7A,SELPLG,PSMB7,RPL38,HTATIP2,NUP155,VDAC1,AZI2,CHMP2B,RAB1A,PSMB9,EIF3G,RPS9,CENPU,RPSA,IDE,CHMP4A,RBL1,HIPK2,STAT1,RPLP1,H2AFX,AP1S1,CHMP4B,SCARB1,MAPK1,XRCC4,AP2S1,CTDP1,RPS2,RAE1,NUP54,CBLL1,ARF1,XPR1,TFRC,HLA-A,WWP2,CCNK,GRK2,RPL17,TANK,RPL19,CREB1,STAT3,PACS2,MSH6,RBM15B,TGFB1,RHOA,KAT2A,RPL8,RCOR1,PACS1,RPL27A,FADD,MAPK3,HSPA1B,HLA-B,KPNA4,RPL32,ELMO1,ZC3H7B,PML,CD81,USF2,CHMP7,DDB1,SNAPIN |
| 7.173e-15 | -32.57 | GSE13547_CTRL_VS_ANTI_IGM_STIM_ZFX_KO_BCELL_2H_UP | MSigDB lists | GSE13547_CTRL_VS_ANTI_IGM_STIM_ZFX_KO_BCELL_2H_UP | 154 | 63 | 17377 | 2626 |
COX5B,PTMS,H2AFZ,CLSPN,RAE1,COPE,TPX2,CDCA8,KLC1,NUF2,FKBP2,DAZAP2,NCAPG,STMN1,PCBP1,SSR1,JAKMIP1,ERH,RPN1,SLC31A1,CCNA2,SP100,CDC42,PPP1R8,AHSA1,KIF14,TTC9C,PRC1,KIF22,CORO1A,RNF5,TACC3,ACSL5,PLK1,NRAS,TACC1,DNAJC9,BRCA1,SEPT7,EDEM2,API5,KIF11,RAB5B,SMAP2,RPA1,NECAP2,TRAM2,POLE,BIRC5,CSK,HNRNPR,PRDX3,PSMD8,NEIL3,NRM,KPNA2,ANP32E,ASNA1,VPS4A,EHD4,GLCCI1,CD81,SLC25A33 |
| 7.419e-15 | -32.53 | GSE12845_NAIVE_VS_PRE_GC_TONSIL_BCELL_DN | MSigDB lists | GSE12845_NAIVE_VS_PRE_GC_TONSIL_BCELL_DN | 193 | 73 | 17377 | 2626 |
SRM,USP7,H2AFZ,RWDD1,UQCR10,SUMO2,PTTG1,ORC1,SNRPD3,KIFC1,ATP2A2,DPYSL2,DUT,PDIA6,CFL1,SNRNP200,RBX1,KIF15,CDC6,NUTF2,ICMT,CCNF,H2AFV,STOML2,HSPB11,CHMP4A,PTPN7,BAZ1B,COX5A,SNRPG,PSMC1,NAA60,HIVEP3,CMAS,MCM10,PHB2,C1orf112,CDK2AP2,CDCA8,CHCHD2,RACGAP1,NDUFA4,CSNK1A1,AP3S1,SRRT,SPAG5,SAC3D1,MCTS1,FBXO5,RFWD3,DTL,TNS3,NDUFV1,H2AFY,HNRNPM,MSH6,SMC4,TERF2,LDHB,FAM49B,TMEM126B,SUGP2,KIF11,RPA1,SDHB,SERF2,QARS,TFDP1,OAZ2,MDH1,PKD2,UBE2C,CD81 |
| 8.432e-15 | -32.41 | GNF2_PCNA | MSigDB lists | GNF2_PCNA | 65 | 37 | 17377 | 2626 |
HNRNPAB,FOXM1,CENPF,RRM1,CDCA8,TPX2,RACGAP1,FANCI,DTL,PA2G4,PCNA,CCNA2,MCM5,PRC1,MSH2,SMC4,GINS1,ASPM,RAD51AP1,KIF15,MYBL2,MKI67,RRM2,DNAJC9,SLBP,NUSAP1,SMC2,MCM2,KIF11,SHCBP1,PRIM1,KIF18B,BIRC5,H2AFX,HMGB2,CCNB2,ESPL1 |
| 8.660e-15 | -32.38 | mitochondrial protein complex | cellular component | GO:0098798 | 251 | 86 | 18223 | 2701 |
NDUFA5,TOMM20,IMMT,NDUFB6,MRPS15,UQCR10,MRPL39,MCCC1,ATP5PF,SDHA,MRPL19,PARK7,MRPL50,PDK2,TIMM23,MRPS27,MRPL34,MICU2,SUCLG2,NDUFB9,APOOL,MRPL32,MRPL57,TIMM50,PPIF,MRPL43,DMAC2,MRPL12,NDUFA7,NDUFB1,VDAC1,FOXRED1,MRPS14,CHCHD3,ANKZF1,MRPL2,DAP3,TIMM13,MRPL55,TIMM29,TIMM17A,TOMM6,CHCHD1,MRPL27,NDUFA11,COX5A,UQCRH,MRPL13,NDUFV2,COX5B,MRPL9,NDUFS1,MRPL42,MRPS2,MRPS26,TIMM21,NDUFA4,COX4I1,ATP5F1B,NDUFS7,NDUFS4,NDUFV1,NDUFA2,NDUFB4,MRPL54,NDUFS8,CYC1,MRPL48,MRPL40,MRPL11,MRPL21,NDUFA3,NSUN4,ATP5IF1,TIMM8B,MRPS10,MRPL16,TOMM40,ATP5MF,CHCHD6,SDHB,ATP5MC3,COX8A,NDUFS5,ATP5F1A,MRPL3 |
| 9.200e-15 | -32.32 | EIF4A3 (eukaryotic translation initiation factor 4A3) | protein interactions | 9775 | 264 | 94 | 17029 | 2761 |
SART1,COX15,SARNP,THOC1,XAB2,SUZ12,SF3B1,RBM8A,MYH9,CUL1,SNRPD3,SDHA,SF3B2,EEF2K,EIF4A3,SRSF4,RAD23B,TRA2B,AQR,CHTOP,SRSF10,SRPK2,PRPF19,CDC5L,FYTTD1,SNRNP200,SNRPB,PPIE,CRNKL1,CUL3,HNRNPF,RNPS1,PFKFB3,PRPF3,SLC25A5,RPS9,DHX15,CLNS1A,SRSF1,DDX17,JAK1,HNRNPR,STK38,ACTB,RRS1,NKAPD1,SMAD4,PDCD4,LZTR1,RPS2,CDC40,SRSF6,RPL15,THRAP3,BLM,SCYL2,NPLOC4,WWP2,ERH,HUWE1,RPL17,EFTUD2,CAPZA1,ANP32A,YBX1,RPL19,FBL,HNRNPM,SPTAN1,YTHDC1,STAU1,WDR18,RPL6,RPL8,ILF3,RPS24,KRAS,SRSF5,PKM,RPL27A,RHOT2,MATR3,PRDX1,CAND1,UPF1,RBMX,CDCA7L,NUP62,DDX5,SRSF3,PPP6R3,SNRNP70,CDK2,PDLIM5 |
| 1.004e-14 | -32.23 | GSE22886_NAIVE_CD4_TCELL_VS_48H_ACT_TH2_DN | MSigDB lists | GSE22886_NAIVE_CD4_TCELL_VS_48H_ACT_TH2_DN | 186 | 71 | 17377 | 2626 |
IMMT,CKLF,DYNLL1,TOR1AIP1,HEXB,TAP1,STARD7,ZFYVE21,SLC25A44,PARK7,FANCI,PCNA,PSMD1,ATP2A2,PHTF1,TARDBP,NUP153,MINPP1,MCMBP,PSRC1,SEC61B,CDC123,CPOX,RRM2,GLO1,CCNF,SUPT16H,RAD51C,DSN1,HINT1,RBL1,HPS5,WDR7,MPV17,H2AFX,BAZ1B,TMEM33,MIF,HJURP,TRIP12,ZCCHC8,RRM1,SMC6,SLC25A12,PSEN1,MYL6B,REEP5,COPB2,TFRC,SLC1A4,PPP1R8,PRC1,ARL6IP1,KNTC1,TMED2,SMC4,TIMM8B,MLEC,NEK7,SEPT8,RDH11,ZNF180,PDCD6,MTHFD2,CCDC86,HMGB2,PGAM1,CCNB2,PDSS2,ESPL1,ZBTB24 |
| 1.147e-14 | -32.10 | CUL5 (cullin 5) | protein interactions | 8065 | 421 | 131 | 17029 | 2761 |
HNRNPAB,LUZP1,CUL1,UBQLN2,SNRPD3,PABPC4,RPL23A,PCNA,TRA2B,TFG,ASB6,CARM1,COPS8,SNRNP200,RBX1,VHL,SNRPB,NSUN2,ELOA,HNRNPF,DCUN1D5,SLC25A5,CBFB,DHX15,GEMIN5,SMAD2,RPS14,WDR4,SOCS4,ACTB,KLHL42,COPS6,ARRB2,ANXA11,WSB2,EWSR1,MRPS2,MUM1,DHX9,TIA1,RPL15,TOP2B,PRPF39,DDX56,EFTUD2,RTCB,CTPS1,RBM3,PABPC1,EEF1D,SOCS5,HP1BP3,POLR2I,MAN1B1,RPS10,RPL6,RPS24,PKM,CAND1,NAP1L1,SYNCRIP,GOLGA2,KLHL15,DCAF11,NUP62,ATP5F1A,SNRNP70,HNRNPDL,RPLP2,KLHL18,PCBP1,PRKACA,SDHA,RPL11,HNRNPA2B1,GRSF1,SOCS6,PDIA6,SPSB3,RPL35,POLR2D,CUL3,CIRBP,RPL38,TOR1AIP2,DNAJA1,ASB13,RPS9,BTBD1,SOCS7,PPP2CA,DNAJC10,HSPA4,HNRNPR,RWDD4,RPLP1,SNRPG,FUS,SMURF1,TUBB,RPS2,ANXA6,AGO2,DCUN1D4,TUT4,GART,AHSA1,FEM1B,COPS7B,RPL19,NAP1L4,UBE2M,PRKDC,RPL8,ILF3,LDHA,TUFM,RPL27A,PRDX1,POLR2A,SNRPA,HSPA1B,TPD52L2,PDCD6,UPF1,PRDX3,HNRNPH3,KHSRP,DDX5,SRSF3,DDB1 |
| 1.147e-14 | -32.10 | MODULE_151 | MSigDB lists | MODULE_151 | 295 | 97 | 17377 | 2626 |
RHOG,CHMP2A,DYNLL1,GYG1,FKBP2,OAT,STMN1,PCBP1,BCAP31,RPL11,RPL23A,RAD23A,SEC11A,ATP6V0B,PCNA,PSMA6,TRA2B,STRAP,MTPN,GPX4,CDC37,RPL29,SEC61B,RPL35,RBX1,SNRPB,RPL38,NDUFB1,VDAC1,SLC25A5,EIF3G,RPS9,RPSA,EIF3H,NSA2,EIF3K,HINT1,RPS27A,PSMD8,RPLP1,UQCRH,BTF3,SNRPG,AP2S1,MYL12B,ATP6V0E1,PPIB,NDUFV2,COX5B,RPS2,C19orf53,CDC40,PHB2,DAP,SRGN,NACA,GADD45G,CIB1,RPL15,NDUFA4,HLA-A,NDUFS4,RB1,EXOSC7,RPL17,DAD1,H2AFY,RPL19,MRPL21,PPA1,EEF1D,ALDH9A1,ABCC1,STAU1,RNASEH2C,MAPKAPK3,RPS10,RPL6,LDHA,RPL8,RPS24,RPL27A,CCT8,PRDX1,ECH1,SDHB,TPD52L2,NAP1L1,KPNA4,MAGT1,RPL32,LRPPRC,MDH1,ACADM,NDUFS5,IDH3B,HIGD2A |
| 1.165e-14 | -32.08 | kidney-carcinoma-renal_cell_carcinoma | COSMIC cancer mutations | kidney-carcinoma-renal_cell_carcinoma | 4601 | 846 | 17385 | 2587 |
RAB14,FGFR1OP,KDM4A,PIGQ,XIAP,DHX8,LACTB2,PPP1R16B,ZNF275,FBXO22,EEF2K,CDKN2C,CDK5,NEK6,RABGAP1L,RAD23B,SRSF4,PDS5B,UPRT,NUP153,RNF26,SENP1,PCBP2,MLST8,PLK3,BAK1,ERCC1,RHOBTB3,GABPA,KIF15,MCL1,TOPORS,SMC2,DIDO1,PPFIA3,MCM2,ICMT,RAB22A,ARF4,KRIT1,TRIM47,SMAD2,MID1IP1,WDR11,RAD18,LIMK1,AXIN1,OGT,RNASEL,FBXL3,TFDP2,SMAD1,E2F2,PDCD4,PFKP,NXT2,SSRP1,DDX42,CLSPN,RHOC,TRIO,RAB23,CERK,TOP2B,ZNRF3,EZH1,EIF2AK4,PDCD7,ITGB5,APH1B,LMNA,MCTS1,ATG4A,DDX56,SLC38A5,RNFT1,INPP5A,MCM5,RIMS3,FBXO7,PHF14,FOXN2,GEMIN4,NUP85,PHKG2,SRSF11,ETV3,DHX29,MYBL2,ITM2A,USP10,BCLAF1,SRSF5,CBFA2T2,MPG,ELK1,RHOB,PTPRF,MAGED2,DTWD1,KPNA1,ETS2,DUSP3,MDH1,SNX14,RNF139,ALS2,EGLN1,RHOG,TRIM41,TRERF1,PTTG1,CHD1L,TPX2,MYH9,NUF2,PRKACA,KTN1,RAB21,PRKD3,FBXL6,DUT,UBA5,NUP107,ANAPC7,RNF19A,RBM15,ARL5A,SNX8,GOPC,IDH3A,MAP4K4,CIRBP,E2F3,ATP6V0A1,MEF2D,DNAJA1,RAB1A,TAZ,FKBP3,DDX17,KIF2A,TAF2,PPP2CA,CDC16,LSM6,CORO1C,HIPK2,RNF38,FUS,PDXK,PPP5C,GEN1,LRCH1,USP13,SRSF6,SESTD1,SIKE1,UBE4A,IP6K2,IL21R,ETS1,IFT27,SLC25A43,NEIL2,PPP1R3B,FBXO3,RPA2,ERH,PDCD10,CLIC4,ITGB8,SUV39H2,HUWE1,PPP1R8,ARF5,ARHGEF1,GEMIN6,UBE3B,FBXL19,GTF2H2,IMPA2,LDHB,PDPK1,STAU1,PPP3CA,TK1,TNFAIP3,DDX24,POLK,LDHA,MTMR12,RAB3IP,DDX39A,PICALM,RPA1,MAGT1,POLE,CCDC6,WNT5B,PITX1,MAPK6,FAM3C,PML,AEN,HMGB2,RGL1,CD81,YWHAH,IGBP1,FAF1,ANAPC4,COX15,DDX47,WDR13,TRIM11,PPP1R15B,SNX15,CSNK2A1,GIT2,BIRC2,SSR1,FANCL,ABL2,RAB8A,PCNA,NUP210,NT5DC1,IL6ST,PIK3R2,XRCC2,ETV6,MYBL1,ASB6,PTPRK,VPS13B,PLK1,SP3,PTPN18,SEPT9,RBX1,SNRPB,RAD51AP1,TLK1,GMFB,LNX2,CDC6,LRP5,UBE2V1,UTP3,BRCA1,PBRM1,RAB5B,USP21,RHEB,TRIM4,FBXO28,CHD3,E2F4,SOCS4,BCL7C,ADAM9,KPNA2,ACTB,DVL1,NUDT11,POT1,NUMB,FUBP1,DNAJB2,CENPF,NKD2,LAMTOR3,RACGAP1,COX4I1,ADCK5,CDK13,RAB6A,DNAJB1,PPP3CB,RAPGEF6,NUS1,VMP1,MBD2,XPA,RBM3,AFF1,MAML1,CYTH1,ABHD2,TRAPPC9,NSDHL,ACSL3,LDB1,KRAS,MAP4K3,EIF2AK1,UBE4B,ICAM2,EIF4G2,IRF5,SDHB,MBIP,CDC27,PALB2,COX7A2L,PRPS2,ZDHHC7,RUVBL2,CCNB2,USP7,SART1,CYLD,TRAF7,FOXM1,XAB2,SUMO2,LAGE3,PCBP1,LYN,DUSP22,BCAP31,RAD23A,RPL11,VAV1,CSDE1,MRPL50,PDK2,PSMA6,MDM2,WDR44,PIN1,PDCD2,RPAP1,CORO1A,MINPP1,AHCYL1,STRAP,SAP30L,SPSB3,DVL2,SNX25,KDM3B,ARHGAP17,BIRC3,BTG2,RAB7A,DNAJC9,NUP155,DCLRE1C,CHMP2B,ARL5B,EIF3H,USP36,SRSF1,DNAJC10,IDE,DHX16,PLEKHG4B,CLK3,RBL1,STK38,MAFK,FASTK,UHRF2,DNAJC17,AP1S1,XRCC3,NCOA1,USP53,SMAD4,RAD51D,INTS2,BCL2L12,MCM10,GOLIM4,CDT1,ARID5A,SMC6,NKRF,HMGN3,ARF1,CSNK1A1,SCYL2,DNAJB9,TFRC,FZD6,PTPN2,HERC3,IRF4,ABCD1,SS18L1,DDX31,POLR1B,ORC3,CAMK2G,RNF5,CNTN5,RHOA,HMGN5,SNX2,TOP3A,ARHGEF12,PCGF1,DDX23,RAB18,TRIM26,KPNA4,PDCD6,FBXO41,ATP6V1D,BIRC5,TFE3,NEIL3,E2F1,PGRMC1,USP20,IMPDH1,RBPJ,NR2F2,PGAM1,RPS6KC1,UBE2C,HIPK3,NUP188,MAX,PDCD6IP,ADAM10,CXXC1,ZDHHC8,TSC22D3,USP39,CUL1,CCNB1,IKBIP,UBE2I,PARK7,RAB4A,SUCLG2,CDC25B,PLCL2,TFG,SMARCE1,DNMT1,CDC5L,ORAI2,KLF10,AKT2,PBK,GNG7,DDX20,AURKB,USP22,GALNT7,CCNF,CBFB,RFC2,SLC25A5,RAB2B,EIF3A,DOT1L,ZMYM3,MAP3K4,ANKRD10,HHEX,WAS,ITGB1,PTPN7,PTPDC1,TRAF5,ZMAT3,HDAC2,PTOV1,DDX58,RECQL,COX5B,DNAJC5,MUT,CHTF18,GSPT2,PRKAA1,VAV2,RRM1,KIF23,CYCS,NOTCH2,PSEN1,JMY,CFLAR,FKBP1A,RPN1,RNF121,MEX3C,SNX18,HDAC7,ATIC,PPP4R1,MSH2,DAPK1,PIGG,FBXL7,CYC1,PIKFYVE,RNF135,GNAI2,ANKHD1,EEF1D,TERF2,SOCS5,PHF10,DDX28,PRIM2,PIGT,MFNG,PIP4K2C,ARID1A,PLEC,RIT1,KDM3A,MAP2K2,PHF6,AKAP1,FAS,PI4K2A,XRCC5,HMGN2,ADSS,CAT,DERL1,PFDN5,TMEM54,ZFP92,RBMX,ACLY,PIAS2,USP32,PPP3R1,VCPIP1,GPI,YY1,MAP3K5,RNF14,CDK2,CABLES1,NRBP1,CDKN2A,DNMT3A,TP53RK,REPS2,RAB11B,TRIP10,URB2,RAF1,SUZ12,RPS6KA1,SF3B1,MAGED1,RAC1,BCL2L1,SDHA,GNB2,EPM2A,PHC2,CRKL,TERF2IP,CCNA2,ZNF75D,SHC1,KDM2A,RALB,SIAH1,LPIN2,SOCS6,CDKN1B,TNPO2,TP53BP2,CDK12,SAP30,CCT2,BRD4,MAPRE2,RFC3,HMGN4,ERF,NARF,CUL3,PKMYT1,CDC23,ASB13,POLG2,ERC1,TRIM28,DHX57,RAD51C,HSPA4,PPP2R5A,JAK1,ACYP1,SAFB,STAT1,SEL1L,FTSJ1,H2AFX,TRIM32,PDCD11,XRCC4,PRPF4B,ADAM23,RHEBL1,POLQ,OTUD5,NCOR2,MECP2,TCF3,CBLL1,BLM,POFUT1,HMG20A,FOXO3,RAB11A,HEATR5B,MAD2L2,JAKMIP1,EBP,WWP2,PIP5K1C,NDUFA2,AHSA1,AXIN2,PTPN11,COPS7B,UBE2M,NCOA2,MSH6,SMC4,JMJD4,LONRF3,NET1,NEK7,RABIF,ADSL,FBXO9,ANAPC2,KIF11,MACF1,MARK2,TSR2,FADD,CBX3,PLD3,GNA12,FBXO21,PFDN4,MFAP1,TFDP1,KHSRP,PPP1R11,DDX5,DUSP11,BRWD3,ESPL1,DDB1,IPO4,GPR89B,DEF6,RORB,POLA2,PIGM,IER2,UBE2E2,ST13,NF1,PTP4A3,UBE2Q1,AGFG1,SIRT2,KIF2C,FKBP2,USP48,UBQLN2,BECN1,MAPK14,RNF103,MBD4,RAP1A,CDC42,EIF4A3,THADA,JAZF1,RAB35,PPP1R12C,RP2,TCEA1,OGG1,ARID4A,TRIM14,SRPK2,COPS8,TRIM8,NCK1,VHL,FOPNL,RRM2,WDR82,PITPNB,KMT2C,SOX4,STK17B,CXXC4,GEMIN5,UEVLD,PPM1G,PQBP1,CAB39,STK11,CLU,CHEK2,COPS6,MRPL13,UBE2D3,PIGN,PPP1R2,PPP1R12A,NACA,CIB1,PCSK7,MED13L,THRAP3,RGS2,XPO7,TTF1,NUP205,ZNF449,BCL2,KNTC1,UBE3C,ZRANB1,MCPH1,N4BP2,CSNK1G3,HP1BP3,ALDH9A1,ZNF189,DAPK3,ARHGAP15,MASTL,UAP1,KLHL15,NFIL3,SIAH2,PITPNA,YWHAZ,NUP62,RBBP4,TOB1,SMARCD1,WASF2,MBD1,TCF12,PRKAB1,SNX27,ASH1L,MDH2,PMS2,SMARCA4,PLAGL2,ORC1,TWF2,CHD1,MXD1,USP5,SAR1A,AKAP8,PPP6C,CS,APOOL,FAM3A,SCYL3,ABI1,DNAL4,EBAG9,MOSPD1,RLIM,POU2AF1,SELPLG,RNF25,PCGF6,METTL2A,ATXN1,GLO1,OGDH,BICD2,FANCE,PDHX,RAD54B,DAP3,TAB2,TULP3,STAT6,HPS5,FKBP5,SCARB1,GAS2,USP11,SMURF1,MAPK1,PPP2R2D,CBX4,DNAJC2,CDS2,MAGEH1,SH2D3A,CASP6,RAE1,EYA1,SCYL1,NUP54,DBF4,CHIC2,MXD4,PIP4K2A,RGS1,FBXO5,FGFR3,CTNNBL1,TANK,TMEM99,ARHGEF2,STAT3,FRMD8,MYO5A,AMPD2,CSNK1G2,ADAM17,HMGN1,HEMK1,ASPM,TFEB,MAPK3,MTMR3,COX8A,SRSF3,ZMIZ1,IDH3B,TERF1,RAB3IL1 |
| 1.165e-14 | -32.08 | renal_cell_carcinoma | COSMIC cancer mutations | renal_cell_carcinoma | 4601 | 846 | 17385 | 2587 |
RAB14,FGFR1OP,KDM4A,PIGQ,XIAP,DHX8,LACTB2,PPP1R16B,ZNF275,FBXO22,EEF2K,CDKN2C,CDK5,NEK6,RABGAP1L,RAD23B,SRSF4,PDS5B,UPRT,NUP153,RNF26,SENP1,PCBP2,MLST8,PLK3,BAK1,ERCC1,RHOBTB3,GABPA,KIF15,MCL1,TOPORS,SMC2,DIDO1,PPFIA3,MCM2,ICMT,RAB22A,ARF4,KRIT1,TRIM47,SMAD2,MID1IP1,WDR11,RAD18,LIMK1,AXIN1,OGT,RNASEL,FBXL3,TFDP2,SMAD1,E2F2,PDCD4,PFKP,NXT2,SSRP1,DDX42,CLSPN,RHOC,TRIO,RAB23,CERK,TOP2B,ZNRF3,EZH1,EIF2AK4,PDCD7,ITGB5,APH1B,LMNA,MCTS1,ATG4A,DDX56,SLC38A5,RNFT1,INPP5A,MCM5,RIMS3,FBXO7,PHF14,FOXN2,GEMIN4,NUP85,PHKG2,SRSF11,ETV3,DHX29,MYBL2,ITM2A,USP10,BCLAF1,SRSF5,CBFA2T2,MPG,ELK1,RHOB,PTPRF,MAGED2,DTWD1,KPNA1,ETS2,DUSP3,MDH1,SNX14,RNF139,ALS2,EGLN1,RHOG,TRIM41,TRERF1,PTTG1,CHD1L,TPX2,MYH9,NUF2,PRKACA,KTN1,RAB21,PRKD3,FBXL6,DUT,UBA5,NUP107,ANAPC7,RNF19A,RBM15,ARL5A,SNX8,GOPC,IDH3A,MAP4K4,CIRBP,E2F3,ATP6V0A1,MEF2D,DNAJA1,RAB1A,TAZ,FKBP3,DDX17,KIF2A,TAF2,PPP2CA,CDC16,LSM6,CORO1C,HIPK2,RNF38,FUS,PDXK,PPP5C,GEN1,LRCH1,USP13,SRSF6,SESTD1,SIKE1,UBE4A,IP6K2,IL21R,ETS1,IFT27,SLC25A43,NEIL2,PPP1R3B,FBXO3,RPA2,ERH,PDCD10,CLIC4,ITGB8,SUV39H2,HUWE1,PPP1R8,ARF5,ARHGEF1,GEMIN6,UBE3B,FBXL19,GTF2H2,IMPA2,LDHB,PDPK1,STAU1,PPP3CA,TK1,TNFAIP3,DDX24,POLK,LDHA,MTMR12,RAB3IP,DDX39A,PICALM,RPA1,MAGT1,POLE,CCDC6,WNT5B,PITX1,MAPK6,FAM3C,PML,AEN,HMGB2,RGL1,CD81,YWHAH,IGBP1,FAF1,ANAPC4,COX15,DDX47,WDR13,TRIM11,PPP1R15B,SNX15,CSNK2A1,GIT2,BIRC2,SSR1,FANCL,ABL2,RAB8A,PCNA,NUP210,NT5DC1,IL6ST,PIK3R2,XRCC2,ETV6,MYBL1,ASB6,PTPRK,VPS13B,PLK1,SP3,PTPN18,SEPT9,RBX1,SNRPB,RAD51AP1,TLK1,GMFB,LNX2,CDC6,LRP5,UBE2V1,UTP3,BRCA1,PBRM1,RAB5B,USP21,RHEB,TRIM4,FBXO28,CHD3,E2F4,SOCS4,BCL7C,ADAM9,KPNA2,ACTB,DVL1,NUDT11,POT1,NUMB,FUBP1,DNAJB2,CENPF,NKD2,LAMTOR3,RACGAP1,COX4I1,ADCK5,CDK13,RAB6A,DNAJB1,PPP3CB,RAPGEF6,NUS1,VMP1,MBD2,XPA,RBM3,AFF1,MAML1,CYTH1,ABHD2,TRAPPC9,NSDHL,ACSL3,LDB1,KRAS,MAP4K3,EIF2AK1,UBE4B,ICAM2,EIF4G2,IRF5,SDHB,MBIP,CDC27,PALB2,COX7A2L,PRPS2,ZDHHC7,RUVBL2,CCNB2,USP7,SART1,CYLD,TRAF7,FOXM1,XAB2,SUMO2,LAGE3,PCBP1,LYN,DUSP22,BCAP31,RAD23A,RPL11,VAV1,CSDE1,MRPL50,PDK2,PSMA6,MDM2,WDR44,PIN1,PDCD2,RPAP1,CORO1A,MINPP1,AHCYL1,STRAP,SAP30L,SPSB3,DVL2,SNX25,KDM3B,ARHGAP17,BIRC3,BTG2,RAB7A,DNAJC9,NUP155,DCLRE1C,CHMP2B,ARL5B,EIF3H,USP36,SRSF1,DNAJC10,IDE,DHX16,PLEKHG4B,CLK3,RBL1,STK38,MAFK,FASTK,UHRF2,DNAJC17,AP1S1,XRCC3,NCOA1,USP53,SMAD4,RAD51D,INTS2,BCL2L12,MCM10,GOLIM4,CDT1,ARID5A,SMC6,NKRF,HMGN3,ARF1,CSNK1A1,SCYL2,DNAJB9,TFRC,FZD6,PTPN2,HERC3,IRF4,ABCD1,SS18L1,DDX31,POLR1B,ORC3,CAMK2G,RNF5,CNTN5,RHOA,HMGN5,SNX2,TOP3A,ARHGEF12,PCGF1,DDX23,RAB18,TRIM26,KPNA4,PDCD6,FBXO41,ATP6V1D,BIRC5,TFE3,NEIL3,E2F1,PGRMC1,USP20,IMPDH1,RBPJ,NR2F2,PGAM1,RPS6KC1,UBE2C,HIPK3,NUP188,MAX,PDCD6IP,ADAM10,CXXC1,ZDHHC8,TSC22D3,USP39,CUL1,CCNB1,IKBIP,UBE2I,PARK7,RAB4A,SUCLG2,CDC25B,PLCL2,TFG,SMARCE1,DNMT1,CDC5L,ORAI2,KLF10,AKT2,PBK,GNG7,DDX20,AURKB,USP22,GALNT7,CCNF,CBFB,RFC2,SLC25A5,RAB2B,EIF3A,DOT1L,ZMYM3,MAP3K4,ANKRD10,HHEX,WAS,ITGB1,PTPN7,PTPDC1,TRAF5,ZMAT3,HDAC2,PTOV1,DDX58,RECQL,COX5B,DNAJC5,MUT,CHTF18,GSPT2,PRKAA1,VAV2,RRM1,KIF23,CYCS,NOTCH2,PSEN1,JMY,CFLAR,FKBP1A,RPN1,RNF121,MEX3C,SNX18,HDAC7,ATIC,PPP4R1,MSH2,DAPK1,PIGG,FBXL7,CYC1,PIKFYVE,RNF135,GNAI2,ANKHD1,EEF1D,TERF2,SOCS5,PHF10,DDX28,PRIM2,PIGT,MFNG,PIP4K2C,ARID1A,PLEC,RIT1,KDM3A,MAP2K2,PHF6,AKAP1,FAS,PI4K2A,XRCC5,HMGN2,ADSS,CAT,DERL1,PFDN5,TMEM54,ZFP92,RBMX,ACLY,PIAS2,USP32,PPP3R1,VCPIP1,GPI,YY1,MAP3K5,RNF14,CDK2,CABLES1,NRBP1,CDKN2A,DNMT3A,TP53RK,REPS2,RAB11B,TRIP10,URB2,RAF1,SUZ12,RPS6KA1,SF3B1,MAGED1,RAC1,BCL2L1,SDHA,GNB2,EPM2A,PHC2,CRKL,TERF2IP,CCNA2,ZNF75D,SHC1,KDM2A,RALB,SIAH1,LPIN2,SOCS6,CDKN1B,TNPO2,TP53BP2,CDK12,SAP30,CCT2,BRD4,MAPRE2,RFC3,HMGN4,ERF,NARF,CUL3,PKMYT1,CDC23,ASB13,POLG2,ERC1,TRIM28,DHX57,RAD51C,HSPA4,PPP2R5A,JAK1,ACYP1,SAFB,STAT1,SEL1L,FTSJ1,H2AFX,TRIM32,PDCD11,XRCC4,PRPF4B,ADAM23,RHEBL1,POLQ,OTUD5,NCOR2,MECP2,TCF3,CBLL1,BLM,POFUT1,HMG20A,FOXO3,RAB11A,HEATR5B,MAD2L2,JAKMIP1,EBP,WWP2,PIP5K1C,NDUFA2,AHSA1,AXIN2,PTPN11,COPS7B,UBE2M,NCOA2,MSH6,SMC4,JMJD4,LONRF3,NET1,NEK7,RABIF,ADSL,FBXO9,ANAPC2,KIF11,MACF1,MARK2,TSR2,FADD,CBX3,PLD3,GNA12,FBXO21,PFDN4,MFAP1,TFDP1,KHSRP,PPP1R11,DDX5,DUSP11,BRWD3,ESPL1,DDB1,IPO4,GPR89B,DEF6,RORB,POLA2,PIGM,IER2,UBE2E2,ST13,NF1,PTP4A3,UBE2Q1,AGFG1,SIRT2,KIF2C,FKBP2,USP48,UBQLN2,BECN1,MAPK14,RNF103,MBD4,RAP1A,CDC42,EIF4A3,THADA,JAZF1,RAB35,PPP1R12C,RP2,TCEA1,OGG1,ARID4A,TRIM14,SRPK2,COPS8,TRIM8,NCK1,VHL,FOPNL,RRM2,WDR82,PITPNB,KMT2C,SOX4,STK17B,CXXC4,GEMIN5,UEVLD,PPM1G,PQBP1,CAB39,STK11,CLU,CHEK2,COPS6,MRPL13,UBE2D3,PIGN,PPP1R2,PPP1R12A,NACA,CIB1,PCSK7,MED13L,THRAP3,RGS2,XPO7,TTF1,NUP205,ZNF449,BCL2,KNTC1,UBE3C,ZRANB1,MCPH1,N4BP2,CSNK1G3,HP1BP3,ALDH9A1,ZNF189,DAPK3,ARHGAP15,MASTL,UAP1,KLHL15,NFIL3,SIAH2,PITPNA,YWHAZ,NUP62,RBBP4,TOB1,SMARCD1,WASF2,MBD1,TCF12,PRKAB1,SNX27,ASH1L,MDH2,PMS2,SMARCA4,PLAGL2,ORC1,TWF2,CHD1,MXD1,USP5,SAR1A,AKAP8,PPP6C,CS,APOOL,FAM3A,SCYL3,ABI1,DNAL4,EBAG9,MOSPD1,RLIM,POU2AF1,SELPLG,RNF25,PCGF6,METTL2A,ATXN1,GLO1,OGDH,BICD2,FANCE,PDHX,RAD54B,DAP3,TAB2,TULP3,STAT6,HPS5,FKBP5,SCARB1,GAS2,USP11,SMURF1,MAPK1,PPP2R2D,CBX4,DNAJC2,CDS2,MAGEH1,SH2D3A,CASP6,RAE1,EYA1,SCYL1,NUP54,DBF4,CHIC2,MXD4,PIP4K2A,RGS1,FBXO5,FGFR3,CTNNBL1,TANK,TMEM99,ARHGEF2,STAT3,FRMD8,MYO5A,AMPD2,CSNK1G2,ADAM17,HMGN1,HEMK1,ASPM,TFEB,MAPK3,MTMR3,COX8A,SRSF3,ZMIZ1,IDH3B,TERF1,RAB3IL1 |
| 1.249e-14 | -32.01 | HORIUCHI_WTAP_TARGETS_DN | MSigDB lists | HORIUCHI_WTAP_TARGETS_DN | 291 | 96 | 17377 | 2626 |
CCNC,SKA3,FOXM1,PTTG1,TPX2,TMEM97,TM9SF3,NUF2,KIF2C,CCNB1,ARL6IP6,PAPOLA,OIP5,UBXN2A,CCNA2,KIF14,AKR1B1,KIF22,BCAP29,CDC25B,MAVS,TIMM50,PLK1,PSRC1,ATG9A,RAD51AP1,PBK,MKI67,GMFB,CKAP2L,NLN,RRM2,NUSAP1,GLO1,CDCA2,AURKB,NDUFA7,PBRM1,ANLN,SLC25A5,H2AFV,ARL5B,ODC1,ASF1B,DNAJC10,SMAD2,KIF18B,CEP55,H2AFX,LRP8,TMEM33,DEPDC1,PPP1R2,HJURP,TOR3A,CDCA8,RRM1,CDCA3,RPL15,KIF23,RACGAP1,PAWR,NCAPG,SPAG5,NAA50,PRC1,GTSE1,CNN2,MRPL48,CENPM,FBL,RPL22L1,LDHB,FDFT1,PHF10,TK1,ASPM,ATP2C1,MYBL2,LDHA,KIF11,SNRPA,ANKRD46,NMT2,TWISTNB,CAT,NAP1L1,CCDC86,CDC27,BIRC5,CSK,FAM83D,HMGB2,CCNB2,UBE2C,ESPL1 |
| 1.273e-14 | -31.99 | FERREIRA_EWINGS_SARCOMA_UNSTABLE_VS_STABLE_UP | MSigDB lists | FERREIRA_EWINGS_SARCOMA_UNSTABLE_VS_STABLE_UP | 148 | 61 | 17377 | 2626 |
H2AFZ,HJURP,MRPL42,MPHOSPH8,CHTF18,CENPF,DBF4,TPX2,C5orf30,KIF23,KIF2C,SNRPD3,BLM,CCNB1,NCAPG,CHD1,GIT2,RGS1,RBM17,ERH,HOMER1,CCNA2,C4orf3,H2AFY,ZFYVE27,KNTC1,FGFR1OP2,SAP30,ERCC1,MND1,KIF15,WDHD1,NUSAP1,CDC6,BRCA1,SMC2,ANLN,API5,CHAF1A,HMGN2,INF2,SLCO4A1,DAP3,KIF18A,ATAD2,SYNCRIP,ZNF330,ODF2,PROSER1,CEP55,HMGB2,KPNA2,XRCC3,FAM126A,SPCS3,TCOF1,BRD9,RPS26,ESPL1,ZNF146,POLQ |
| 1.362e-14 | -31.93 | FLECHNER_BIOPSY_KIDNEY_TRANSPLANT_OK_VS_DONOR_UP | MSigDB lists | FLECHNER_BIOPSY_KIDNEY_TRANSPLANT_OK_VS_DONOR_UP | 531 | 148 | 17377 | 2626 |
H2AFZ,PNISR,COPA,UBQLN2,SNRPD3,OAT,PARK7,DST,RAB8A,GOT2,DPYSL2,IL6ST,NUP153,SPTSSA,SRP72,SP3,RHOBTB3,DPM1,TOPORS,MCL1,PRKRA,ARF4,KRIT1,HSPB11,TMED10,LUC7L3,OGT,KPNA2,CLU,ROCK1,ATP6V0E1,PPIB,RECQL,MAPRE1,MUT,PPP1R2,NACA,DHX9,TOP2B,CDK13,CYCS,CFLAR,RB1,SUB1,ARPC5,CAPZA1,RBM3,AFF1,MVP,EEF1D,MORC3,SRSF11,TSPYL4,ZMYND11,ACSL3,AMD1,ITM2A,DCTD,EIF4H,CAT,NAP1L1,FNTA,DUSP3,MDH1,PDLIM5,TOB1,NDUFA5,IMMT,DYNLL1,RAC1,ANK3,TOR1AIP1,MYH9,CREBL2,ATP6V1B2,BCAP31,HNRNPA2B1,APLP2,ATP2A2,MTMR4,SIAH1,DUT,TARDBP,CHTOP,AHCYL1,MINPP1,F2R,ATF2,ABI1,CCT2,SHOC2,BIRC3,HMGN4,E2F3,DNAJA1,RAB1A,PSMB9,H2AFV,TXNL4A,SERP1,SRSF1,DDOST,HNRNPR,STAT1,H3F3A,ZNF146,NDUFS1,SRGN,GTF3A,HMGN3,UBE4A,AP3S1,RAB11A,HLA-A,ADD3,TANK,ANP32A,LTN1,ANXA5,PTGES3,CREB1,CITED2,STAT3,NCOA2,TMX1,SLC25A1,ELOVL5,HMGN1,RHOA,GALC,SNX2,NEK7,JTB,FBXO9,PICALM,CBX3,PDCD6,PARG,FAM3C,BBX,LY75,MEGF9,DDX5,HMGB2,YWHAH,TERF1,IFI16,GCSH |
| 1.604e-14 | -31.76 | GNF2_CDC2 | MSigDB lists | GNF2_CDC2 | 60 | 35 | 17377 | 2626 |
HJURP,FOXM1,CENPF,PTTG1,CDCA3,RRM1,CDCA8,TPX2,NCAPG,FANCI,KIFC1,PCNA,CCNA2,PRC1,SMC4,RFC3,ASPM,KIF15,MYBL2,MKI67,RRM2,DNAJC9,NUSAP1,SMC2,MCM2,CCNF,KIF11,SHCBP1,PRIM1,KIF18B,BIRC5,H2AFX,HMGB2,CCNB2,UBE2C |
| 1.609e-14 | -31.76 | translation | biological process | GO:0006412 | 375 | 115 | 17256 | 2622 |
KARS,CYLD,RPLP2,RWDD1,MRPS15,MRPL39,EIF3D,EFL1,EIF1B,RBM4,MRPL19,PAIP1,PABPC4,EEF2K,RPL23A,RPL11,MRPL50,FARSA,IARS,MRPS27,MRPL34,EIF5,MRPL32,MRPL57,RPL29,LARS,RPL35,HARS,MRPL43,RPL38,MRPL12,NDUFA7,POLG2,MRPS14,EIF3G,RPS9,EIF3H,RPSA,EIF3A,RPL37,EIF3K,GEMIN5,MRPL2,DAP3,MRPL55,RPS27A,RPS14,CHCHD1,MRPL27,EIF2D,PPA2,RPLP1,FTSJ1,IARS2,QRSL1,MRPL13,RPS26,ZNF598,PDF,RPS15,MRPL9,RPS2,MRPL42,MRPS2,DHPS,AGO2,GSPT2,MRPS26,RPL15,SECISBP2,GFM2,MCTS1,EIF2S2,GATC,RPL17,EFTUD2,PELO,RRBP1,MRPL54,LTN1,RPL19,MRPL40,MRPL48,MRPL21,MRPL11,GTF2H2,PPA1,PABPC1,RPL22L1,EEF1D,CARS2,EIF5A,EIF3L,DHX29,NOA1,RPL6,RPL8,TUFM,RPS10,MRPS10,RPS24,MRPL16,EIF2A,EIF4H,EIF4G2,RPL27A,GUF1,ABCF1,TARS,RPL36,EPRS,RPL32,QARS,CPEB2,MRPL3 |
| 1.841e-14 | -31.63 | WINNEPENNINCKX_MELANOMA_METASTASIS_UP | MSigDB lists | WINNEPENNINCKX_MELANOMA_METASTASIS_UP | 149 | 61 | 17377 | 2626 |
PRPF38B,IMMT,CENPF,PTTG1,OLA1,CDCA8,RACGAP1,NUF2,KIF2C,NANS,CCNB1,SUPT7L,NCAPG,SPAG5,CREM,PCNA,PHF14,PRC1,TIMELESS,GEMIN6,KNTC1,CHTOP,TMEM136,OGG1,HTRA2,MRPL32,MSH6,SRSF10,TK1,NASP,PRIM2,ASPM,NUDT4,MAP4K4,RRM2,MRPS10,CDC6,SMC2,DNAJA1,ANLN,C9orf40,H2AFV,SHCBP1,KIF11,TARS,ARF4,IWS1,HSPA4,ATAD2,KIF18B,SURF4,BIRC5,NEIL3,ZNF367,RBMX,CDCA5,CEP55,KPNA2,TCOF1,SNRPG,CCNB2 |
| 1.886e-14 | -31.60 | MORF_RPA2 | MSigDB lists | MORF_RPA2 | 184 | 70 | 17377 | 2626 |
POLA2,IMMT,NUP188,PRKCSH,SUMO2,AGPAT1,CSNK2A1,ORC1,USP5,HNRNPA2B1,TXLNA,CS,TCEA1,KDM3B,PPIF,SNRNP200,AATF,HMGN4,PPIE,PKMYT1,OGDH,ESYT1,MCM2,TAZ,SERP1,TIMM17A,E2F4,ATXN2L,COPS6,USP11,B4GALT3,SMNDC1,HDAC2,MRPL9,PHB2,LANCL1,XPO7,PARN,AP3S1,GTF2F1,EBP,RPA2,PSMD2,RPN1,DNAJC8,EIF2S2,CAPZA1,ARL6IP1,NAP1L4,MLEC,PRKDC,WDR18,LDHA,PSMA1,ADSL,MTX1,SEPT7,ELK1,MEN1,POLR2A,RXRB,MFN2,CSK,LRPPRC,NUP62,TCOF1,CDK2,NUDT3,DDB1,SMARCD1 |
| 1.898e-14 | -31.60 | GSE21927_SPLEEN_C57BL6_VS_EL4_TUMOR_BALBC_MONOCYTES_DN | MSigDB lists | GSE21927_SPLEEN_C57BL6_VS_EL4_TUMOR_BALBC_MONOCYTES_DN | 188 | 71 | 17377 | 2626 |
NUP188,NDUFB6,URB2,RAC1,CSNK2A1,STAM,FANCL,NAPG,UTP18,DNAAF2,GRSF1,UBA5,MRPL34,NOC2L,ECD,APOOL,PRPF19,SEC61B,NXT1,AATF,RNF25,KIF15,POLR2D,PSMG1,SLBP,RFC2,MRPS14,ODC1,RPSA,EIF3A,STOML2,PRIM1,ALG3,PSMD8,PPM1G,C1orf109,IARS2,UQCRH,PDCD11,MIF,DNAJC2,NDUFS1,NSMCE4A,MRPS2,PDAP1,MYL6B,RAB11A,FASTKD3,DDX56,ERH,BUD31,YBX1,MRPL40,TTLL12,SMC4,NUDC,MOB4,TIMM8B,POLR2I,NASP,MAPKAPK3,GTPBP4,EIF4G2,ABCF1,EPRS,KIF18A,ATAD2,NEIL3,STX18,COX8A,BYSL |
| 1.898e-14 | -31.60 | GSE36476_CTRL_VS_TSST_ACT_40H_MEMORY_CD4_TCELL_OLD_DN | MSigDB lists | GSE36476_CTRL_VS_TSST_ACT_40H_MEMORY_CD4_TCELL_OLD_DN | 188 | 71 | 17377 | 2626 |
TMEM106C,SUCLG1,UCK2,TPX2,EBNA1BP2,NIT2,KIF2C,CCNB1,STMN1,POLR3K,FANCI,SNUPN,IARS,GOT2,RNASEH2A,TALDO1,RFC3,RBX1,RAD51AP1,MRPL12,KIF15,PSMG1,RRM2,CDC6,AURKB,SMC2,MCM2,MRPS14,PRIM1,RAD51C,PPM1G,CEP55,MPV17,MLYCD,KPNA2,TUBB,SEPHS2,GCLM,MCM10,HJURP,CENPF,RACGAP1,BLM,NCAPG,MYL6B,RMI1,SPAG5,DTL,IRF4,TNS3,PSMD2,GART,BDH1,DAPK1,CENPM,CYC1,MRPL11,ZNF189,NUDC,TXNL1,TK1,CREG1,ASPM,ADSL,KIF11,SLCO4A1,KEAP1,WDR76,CCNB2,PGAM1,ESPL1 |
| 1.974e-14 | -31.56 | GO_NCRNA_METABOLIC_PROCESS | MSigDB lists | GO_NCRNA_METABOLIC_PROCESS | 490 | 139 | 17377 | 2626 |
DDX47,NOP2,EBNA1BP2,SNAPC4,KRR1,RPL23A,PA2G4,NOL11,EIF4A3,INTS1,RNASEK,TRMU,POP7,RPF2,FTSJ3,METTL1,RPP25,LARS,EXOSC6,HARS,NOL8,NSUN2,UTP3,PRKRA,MAK16,RPL37,SMAD2,RPS27A,RPS14,WDR4,IARS2,QRSL1,RNASEL,RRS1,OSGEPL1,SMAD1,RPS26,CTU2,RPS15,POLR2K,RPL15,SRRT,METTL3,DDX56,EXOSC7,INTS7,GEMIN4,CPSF4,PPA1,NSUN4,CARS2,POLR2I,ELL2,TEX10,TYW1,UTP15,RPS10,RPL6,RPS24,EXOSC9,RPL36,EPRS,POLR2J,QARS,TYW5,DTD1,TSEN15,CDKN2A,KARS,SART1,TP53RK,RPLP2,MRPL39,LAGE3,C2orf49,RPL11,HNRNPA2B1,FARSA,IARS,DUS4L,CD3EAP,UTP18,GRSF1,UBA5,EXOSC1,INTS12,RPRD1B,RPL29,RPL35,POLR2L,POLR2G,RPL38,POLR2D,METTL2A,GAR1,POLG2,RPS9,RPSA,NSA2,DUS3L,LSM6,DGCR8,TBL3,FTSJ1,RPLP1,PPA2,FAU,PDCD11,CSNK1D,INTS2,RPS2,TRMT6,GTF3A,RRP36,PNO1,GTF2F1,CCNK,GTPBP3,GATC,RPL17,RPL19,POLR1B,FBL,ERI3,GTF3C6,RPRD1A,WDR18,RPL8,BMS1,RPL27A,TSR2,TARS,POLR2A,UTP20,RPL32,TAF6,BYSL,TYW1B,DDX52 |
| 2.300e-14 | -31.40 | ribonucleoprotein complex subunit organization | biological process | GO:0071826 | 216 | 78 | 17256 | 2622 |
SART1,NOP2,XAB2,SF3B1,EIF3D,USP39,EFL1,SNRPD3,BRIX1,EDC3,RPL23A,RPL11,SNUPN,ZNHIT6,RPF2,KHDC4,EIF5,STRAP,SRPK2,PRPF19,SRSF10,SNRNP200,SNRPB,CRNKL1,POLR2D,CIRBP,RPL38,DDX20,PRPF3,TXNL4A,LUC7L,CLNS1A,RPSA,EIF3A,SRSF1,GEMIN5,NIP7,RPS14,LUC7L3,EIF2D,ATXN2L,SNRPG,RRS1,GEMIN7,RPS15,LIME1,SRSF6,AGO2,DHX9,KLC1,PRPF39,GFM2,CDC73,PRPF18,MCTS1,KIF5B,PELO,GEMIN6,GEMIN4,PTGES3,MRPL11,NSUN4,LUC7L2,PPAN,YTHDC1,DDX28,WDR18,RPL6,RPS10,SRSF5,EIF2A,EIF4H,PATL1,SF3A2,DDX23,RBMX,PRMT7,RUVBL2 |
| 2.484e-14 | -31.33 | bile_duct | COSMIC cancer mutations | bile_duct | 15555 | 2418 | 17385 | 2587 |
HECA,ZBTB10,ABCC10,HEXB,CCNL2,FBXO22,EEF2K,RAD23B,ATP13A3,DNM2,ZNRD1,FTSJ3,USP34,ERCC1,NRAS,EHMT1,KIF15,HNRNPF,WDHD1,MIER2,DIDO1,MCM2,RAB22A,SMAD2,MID1IP1,RPS27A,OGT,MPV17,COX5A,SMAD1,ZNF75A,ANXA11,SLC25A33,SEC61G,GGA1,MUM1,TRIO,CUTA,RAB23,KCTD17,HAUS4,EIF2AK4,APH1B,CDC73,MYL6B,ATG4A,TMEM179B,PDXP,SMC3,GEMIN4,MVP,NUP85,PABPC1,NSUN4,PPA1,IFRD1,AGGF1,FOXK1,RBM42,GTPBP4,MAP7D1,MRPL16,ELK1,EIF4H,RDH11,MAGED2,KPNA1,ETS2,TYW5,WIPI2,RUFY3,PDLIM5,ACSF2,EXOC3,RHOG,STARD7,C5orf30,VTI1A,SLC35B2,INO80E,RCOR3,LCLAT1,CPNE3,KIAA1147,RBM23,ZNF420,AHCTF1,TBC1D22A,TBC1D14,GMEB1,NSFL1C,SEPT11,GPD1L,ZC3H3,ARL5A,PDCL3,SNX8,ERMP1,EID1,IDH3A,POLR2D,HTATIP2,MEF2D,TMEM147,GSTCD,TANC1,MAT2A,VPS26B,CORO1C,NSMCE2,CAMKMT,PPP5C,PITRM1,TUBB,COMMD10,ZNF445,SRSF6,HABP4,CCM2,FLOT1,BTN3A1,ATG2B,ABHD14B,PPP1R3B,ZBTB45,HUWE1,ZNF260,NAA50,ANXA5,LTN1,UBE3B,NAP1L4,ZNF710,ST8SIA2,SPTAN1,STAU1,DDX24,TACC1,MRS2,LDHA,HEBP2,LLPH,RAB3IP,TTC33,PICALM,SH3BP5,SLC19A1,ACOX1,FAM3C,AEN,PARP10,YWHAH,THAP5,GPATCH4,FAM129A,TRIM11,YTHDC2,SNX15,RBM8A,ENSA,NENF,SND1,RUFY1,TRIM65,ZER1,PRNP,KRR1,RAB8A,NUP210,NT5DC1,NOC2L,EIF5,TACC3,VPS13B,PTPN18,MIOS,SNRPB,MBLAC2,CDC6,UTP3,PBRM1,ODC1,USP21,TRAM2,FBXO28,BCL7C,ARRDC1,ADAM9,DVL1,NUMB,ZNF564,FUBP1,C1orf74,PARP12,ZCCHC9,CENPF,LAMTOR3,CHCHD2,NCKAP1,LYRM2,RSAD1,TNS3,SUB1,RINL,SSBP3,KIF13B,MBD2,XPA,AHCY,RBM3,LRSAM1,HDHD2,NTPCR,NSDHL,AMD1,CAMSAP1,ZNF761,METTL22,ICAM2,STYXL1,APPL1,BBS12,RXRB,SDHB,PCM1,GALNT2,TMEM168,NLRC5,RUVBL2,BTBD10,MYO9A,CCNB2,USP7,GLT8D1,RPLP2,SUCLG1,ARID2,TMX4,SLC2A1,ATP6V1B2,PCBP1,LYN,BCAP31,VAV1,TMEM69,MRPL50,PSMA6,ZNF473,BRPF3,TARDBP,BCAP29,CTDSP2,PRPF19,PPIF,KDM3B,MND1,CLCN3,BIRC3,RAB7A,ANKRD33B,PPIE,CHMP2B,VDAC1,EIF3H,TMEM201,GLOD4,IDE,DHX16,UHRF2,XRCC3,CHMP4B,PARD3,BCL2L12,C19orf53,MCM10,KLHL21,PDAP1,TMX3,CDCA8,ARF1,SLC12A9,TUBGCP2,DNAJB9,HOMER1,POLR1B,RNF5,RBM15B,PPAN,RHOA,RPRD1A,BTAF1,TOP3A,ARHGEF12,PCGF1,DDX23,RAB18,CACNB1,TRIM26,PDCD6,ATP6V1D,L3MBTL3,FAM110A,NEIL3,CTBS,BBX,IMPDH1,TAF12,NR2F2,PGAM1,HIPK3,IFI16,TXN,NUP188,H2AFZ,PRKCSH,USP39,UBE2I,PARK7,SLC25A37,ASPHD2,ZNF428,TRA2B,SUCLG2,CISD2,TAF5L,SMARCE1,ZNF800,CDC5L,ZNF524,SGCE,OSBP2,NSUN2,USP22,CLNS1A,EIF3A,ZMYM3,DOT1L,IWS1,ANKRD10,WAS,KIF18B,TPP2,C1orf109,ZMAT3,B4GALT2,PRPF38B,RECQL,C9orf78,EWSR1,GADD45G,RRM1,ACAP1,B4GALT1,CYCS,FAM136A,SUPT7L,TMEM165,CNOT3,WDR48,SPAG5,RTKN,CEP104,EXOSC7,KLHL5,LRRC8D,PPP4R1,MSH2,PIGG,FBXL7,OSTF1,MRPL40,TNRC18,SYTL3,FAM171A1,APOL1,EIF5A,GCC2,PRIM2,ELL2,RDH10,MFNG,RPS24,GORASP2,CAPZA2,ADRB2,CCT8,MTR,PHF6,PFDN5,SLCO4A1,TTC13,GOLGA2,RBMX,PIAS2,APPL2,SAMD8,NUDT3,CDKN2A,ZNF511,ATXN3,RAF1,KIAA0232,C2orf49,EPM2A,CD320,CCNA2,MTMR4,BRI3,TP53BP2,AQR,RBM12B,ILKAP,CDK12,SAP30,BRD4,DRAP1,NARF,LRRC8A,ELP4,ABHD11,PKMYT1,ASB13,SERP1,TRIM28,SUPT16H,EIF3K,CHMP4A,ATF6,XRCC4,PRPF4B,ADAM23,NDUFS1,DEPDC1,MECP2,SECISBP2,HMG20A,WWP2,SLC25A36,JAKMIP1,DNAJC8,AXIN2,CITED2,JMJD4,ANKRD37,KAT2A,TMEM126B,RABIF,ADSL,PACS1,BMS1,KCNQ1,ARSK,MACF1,KIF11,KLF6,COMMD4,SMAP2,FADD,SH3GLB1,MYO1F,CBX3,TMEM127,INF2,PPP1R11,DUSP11,DDX5,WDR62,TAF6,ESPL1,PURA,DDB1,DEF6,FAM83G,IPO4,UBL3,PIGM,NAT9,LYRM4,GPR132,UBE2Q1,PTP4A3,BRIX1,MRPL19,ZNF696,SF3B2,PCYOX1L,CDC42,GOT2,JAZF1,HADHB,RPF2,SLC35C2,CNNM3,CARM1,SRPK2,WDR41,LARS,ZCCHC10,CCDC138,LRBA,SUMF2,KMT2C,OGFR,PRPSAP1,ASF1B,RPL37,MAN2A2,EIF4ENIF1,NIP7,U2SURP,MIA2,ATP6V0E1,PPP1R2,PM20D2,XPNPEP3,RGS2,LYAR,FAM89B,POLR2I,TRAFD1,SUGP2,GBA,SYVN1,DAPK3,ARHGAP15,MASTL,UAP1,NFIL3,FN3KRP,YWHAZ,CTSA,TMEM14A,TOB1,TSEN15,ADNP2,TCF12,PRKAB1,MDH2,SMARCA4,ORC1,RRN3,UBXN2A,IARS,CD3EAP,KIF14,EXOSC1,CS,CLTB,DNAL4,CSTF1,POU2AF1,UBQLN4,NXT1,HPDL,PGGT1B,SELPLG,SMU1,ATXN1,GLO1,OGDH,BICD2,CADM1,EDEM2,HERPUD2,TOLLIP,FANCE,MBD3,PDHX,RPS9,ALKBH6,SURF4,DUS3L,ARNTL,ANP32E,FKBP5,TMEM101,CCDC125,ABCA1,PDCD2L,GCLM,RAE1,NUP54,CHIC2,PAWR,MXD4,DCUN1D4,PIP4K2A,XPR1,KIF5B,KLHL20,SEC24C,RRBP1,ARHGEF2,LDLRAD3,STAT3,MYO5A,NIPAL3,AMPD2,TXNL1,PHF20L1,DCAF6,FAM49B,TMEM39A,ATP2C1,RFFL,COG1,RCOR1,PRMT2,TFEB,LEMD2,UPF1,ELMO1,ZC3H7B,DTX4,ZMIZ1,TERF1,HRAS,CCDC93,FGFR1OP,TMED7,PIGQ,AGPAT1,CNTROB,PPP1R16B,MIS12,GSDMB,TTC9C,PDS5B,NUP153,SENP1,PGAP2,TMEM115,DCUN1D5,PLEKHF2,BRMS1,PWWP2B,TRIM47,WDR11,AXIN1,SMG9,TRIM52,LONP2,NDUFV2,PHF23,CERK,SLC4A2,EZH1,ITGB5,LMNA,MCTS1,DDX56,EIF2S2,SLC38A5,FOXN2,CARS2,PRRC2A,C16orf72,RB1CC1,ZMYND11,PGS1,MYBL2,UHRF1BP1,SRSF5,MPG,MATR3,CYB5A,NCDN,POLR2J,SETD3,PTAR1,CNOT6,NDE1,EGLN1,ZNF207,ANKRD27,ABCA3,IVNS1ABP,RMI2,MON1B,TMEM97,NIT2,NUF2,ZNF267,TCF19,TMEM161B,KTN1,APP,PRKD3,CLUAP1,ATP2A2,UTP18,DUT,ZCCHC2,ANAPC7,RNF19A,FAM76B,CLN6,TMEM9,GCC1,RNF169,ADCY7,ATP6V1G1,ENPP4,RNPS1,CDCA2,FKBP3,GPR137,DDX17,CHCHD3,PEX5,CDC16,HIPK2,MBOAT1,TICAM1,ZBTB11,ANXA6,TMBIM4,GMCL1,UBE4A,IL21R,ETS1,WRB,ZNF92,PNO1,CAPN2,ADD3,SUV39H2,TTLL12,TPCN1,TMX1,LYPLA2,HNRNPM,LDHB,PPP3CA,NUDT8,POLK,JTB,EMP3,MTMR12,ZP3,PDE3B,KIF18A,CCDC6,WNT5B,MAPK6,C4orf46,LY75,SLC25A19,RGL1,PSAP,WDR76,IGBP1,FAF1,SNAPIN,COX15,THOC1,AGRN,GNPDA1,GPBP1L1,PPP1R15B,CSNK2A1,EBNA1BP2,GIT2,BIRC2,ATPAF1,DLG5,ABL2,XRCC2,ZFYVE27,MCMBP,PTPRK,CDC37,SP3,METTL1,EXOSC6,HARS,GMFB,ESYT1,ANLN,RAB5B,RHEB,DPYSL3,TBC1D17,TIMM13,CDCA4,TONSL,NRM,NAGLU,ACTB,ZNF45,TMUB1,CTCF,ASAH1,DOCK11,CRLF3,LRRC14,NUS1,SLC27A4,AFF1,MDFIC,MAML1,CYTH1,NQO2,UTP15,EIF2AK1,EIF4G2,ZDHHC3,MOSPD3,ITPRIPL1,CDC27,SNAP23,TBPL1,PRMT7,KCTD7,NDUFA5,CYLD,UGP2,DYNLL1,COPE,HCFC1R1,ZADH2,GGPS1,RAD23A,PDK2,ATP6V0B,STRBP,DUS4L,MRPL34,PDCD2,SAP30L,SLC39A9,CLPTM1,RPL29,RPL35,BTG2,DNAJC9,MTMR6,FRAT2,NFATC2,KDM1B,ARL5B,USP36,CCDC127,MRPL2,ATP1A1,CLK3,PSMD3,MAFK,CEP55,NDUFA11,DNAJC17,ZNF436,NCOA1,SLC25A39,ZC3HC1,ZNF146,ATXN7L2,CDC40,GOLIM4,SMAP1,RRP15,DAP,GNE,SMC6,ARFIP2,NKRF,CHAC2,BZW2,WRNIP1,SS18L1,CENPM,PTGES3,CAMK2G,MLEC,ZNF202,PPWD1,FAM50B,RHOT2,NEU1,TPD52L2,GOLGA7,TWSG1,GLG1,PGRMC1,FAM126A,RPS6KC1,UBE2C,PPCS,NDUFB6,TMEM41B,ZDHHC8,PLXNA1,CCNB1,SLC20A1,COMMD6,ABHD14A,POLR3K,C14orf119,ASAP2,SNUPN,TFG,PLCL2,SEH1L,ATG9A,PBK,MKI67,DDX20,AMDHD2,SLC17A5,GALNT7,CCNF,FOXRED1,PTER,WDR4,DHTKD1,TRAF5,HDAC2,PWWP2A,HSPH1,MAPRE1,CHTF18,ADO,KIF23,SLC35B1,NOTCH2,JMY,FKBP1A,SLC31A1,SNX18,ATIC,ATP6V0A2,PIKFYVE,RNF135,LPCAT1,EEF1D,TMED2,PHF10,FTL,DDX28,ZNF84,SIGMAR1,PIP4K2C,RIT1,PLEC,KDM3A,SF3A2,FAS,EPRS,ZNF777,TMEM54,QARS,PPP3R1,TCOF1,CABLES1,NRBP1,DNMT3A,RWDD1,CKLF,TRIP10,SF3B1,CAST,SUZ12,RPS6KA1,RAC1,GPR89A,OLA1,SNN,GNB2,FLAD1,APLP2,KDM2A,CDKN1B,TNPO2,TALDO1,GPX4,ATP13A1,RFC3,MAPRE2,ERF,CUL3,SLBP,H2AFV,GAR1,PSMB9,POLG2,DHX57,NSA2,HSPA4,MRPL55,JAK1,TBL3,SEL1L,H2AFX,KLHDC4,B4GALT3,PDCD11,ATMIN,POLQ,POU3F2,OTUD5,NCOR2,ANKRD13D,PKP4,SCAMP3,CDCA3,SLC25A12,BLM,TMCC3,GTF2F1,RPL17,CRAT,AHSA1,PRC1,UPF2,COPS7B,SLC38A10,CNPY3,UBE2M,IFT46,TMEM160,TSHZ1,ZFP64,DENND4C,WDR18,RPL8,ILF3,LRRC1,RHOT1,TSR2,MARK2,ECH1,PRDX1,PLD3,NUCB1,GNA12,FBXO21,C1orf131,PRDX3,PFDN4,HNRNPH3,TFDP1,STX18,KHSRP,ASNA1,CPEB2,SSSCA1,VPS29,BYSL,S100PBP,MIB2,IER2,PTMS,NOP2,UBN1,NF1,DCAF15,ALKBH5,MOGS,TAF6L,MAPK14,BECN1,SNAPC4,RNF103,BCAT2,MBD4,C18orf32,METTL14,ZNHIT6,IMPAD1,RCSD1,PHTF1,SRI,KIF22,ZBTB22,NFU1,OGG1,TRIM14,ELOF1,COPS8,FYTTD1,TRIM8,RRM2,SOX4,ABHD5,CXXC4,UBTF,PAF1,UEVLD,SPATA2,PQBP1,IARS2,ATXN2L,GALNT10,STARD3NL,RPS15,PIGN,AGTRAP,CIB1,XPO7,SRRT,ZNF449,CAPZA1,GLTP,KIFAP3,BCL2,N4BP2,HP1BP3,THNSL1,ISG15,CAND1,GNAS,TSC1,RBM25,CDCA5,ZFP90,NANP,RBBP4,ZBTB24,SMARCD1,MBD1,WASF2,MMACHC,TOMM20,IFI27L1,GNPNAT1,MPHOSPH8,HNRNPUL2,CHD1,MEAF6,C2orf68,CCDC50,AKAP8,PARL,RPN2,CHTOP,FAM3A,F2R,SCYL3,TMEM14C,ABI1,HTRA2,MOSPD1,RLIM,FAM172A,ZNF500,PSMB7,NLN,WIPF1,BOLA1,BUD13,NDUFB1,PEF1,EIF3G,BTBD1,TAB2,CHCHD1,TULP3,WDR59,CANT1,SCARB1,GAS2,USP11,SMURF1,PPP2R2D,TSPAN5,CDS2,MAGEH1,MRPL42,EYA1,CDK2AP2,MRPS26,LETMD1,KLF13,HDDC2,RGS1,MAN1A1,FBXO5,GART,TANK,BRD7,MRPL11,SAMD4B,ZDHHC18,GTF3C6,POLR3GL,WDR81,MEN1,ZNF407,MFN2,COX8A,ZRANB2,SRSF3,MBD6,ATP6V1C1,IDH3B,TATDN1,TSC2,LACTB2,CMTM6,RBM4,ZNF275,RPL23A,CDKN2C,USF1,MECR,AP1M1,UPRT,CRY2,ECD,RNF26,TIPARP,LRRC59,ANKRD9,RHBDD2,MGAT5,BAK1,ZNF559,RHOBTB3,GABPA,WBP1,NUTF2,ARF4,GINS4,KRIT1,BOLA3,AHNAK,RAD18,PDRG1,RNASEL,CHPF2,OAZ1,SMNDC1,PDCD4,NXT2,HIVEP3,KIAA0100,CLSPN,RHOC,DHX9,PDCD7,PSMD9,HAUS2,COPB2,CD59,TFAP4,RNFT1,RIMS3,EFTUD2,FBXO7,CPSF4,MRPL21,PHKG2,LUC7L2,SRSF11,EIF3L,MTA2,TYW1,USP10,ITM2A,SSR2,BCLAF1,MTX1,SFXN5,FNTA,PDLIM1,TMEM159,MRPL3,ALS2,FAM72A,TRIM41,KARS,NQO1,POC1A,ANK3,PTTG1,TPX2,TBC1D13,DAZAP2,STMN1,C19orf48,REPS1,ABHD16A,FBXL6,SH3BP1,MTA1,UBA5,CLCN6,INTS12,C8orf59,RPRD1B,CGGBP1,CPNE1,SEC61B,POLR2L,FAM118B,GOPC,E2F3,CIRBP,RPL38,CRNKL1,PFKFB3,GORAB,RAB1A,GIGYF1,TMEM184C,PPP2CA,KIF2A,CCDC14,LSM6,RNF38,SNRPG,DMWD,USP13,ZFP91,TRMT6,IP6K2,WDR5,SLC25A43,IFT27,PMVK,NEIL2,RRP36,SRXN1,RPA2,PSMD2,CLIC4,PDCD10,CBWD2,COQ4,ITGB8,ARF5,ARHGEF1,FBXL19,TTPAL,UTP20,GPS2,DBI,SSNA1,MRFAP1L1,CD81,TMEM131,WDR13,FANCI,PAPOLA,CREM,FANCL,GLIS2,IL6ST,POP7,SLC44A1,MTPN,ASB6,PLK1,RPP25,SEPT9,CELSR2,RBX1,APH1A,RAD51AP1,CKAP2L,PSMG1,UBE2V1,EAF2,IL12RB1,KRTCAP2,LUC7L,LSG1,NECAP2,C1orf122,TRIM4,AGPAT2,CHD3,ZNF367,E2F4,PRPF4,BEND6,CLN3,DNAJC30,NGLY1,POT1,MYL12B,CCDC137,RMND5A,HJURP,PHB2,DNAJB2,FAM53C,NKD2,SDC2,KLC1,CDK13,ADCK5,COX4I1,DNAJB1,RAB6A,ARID1B,C1GALT1,MLX,UBE2Q2,CCP110,ZNF746,ARL6IP1,CTR9,NIPSNAP1,ABHD2,DCAF8,ACSL3,LDB1,MAP4K3,ARMC8,NMT2,IRF5,RPL36,HAUS8,MBIP,ORMDL2,COX7A2L,ZDHHC7,SIL1,FAM122A,UNC13C,BCCIP,SART1,TRAF7,NDUFAF2,TOR1AIP1,ZNF416,LAGE3,ZFYVE21,TM9SF3,RRAGC,ZNF121,OIP5,NRF1,WDR44,PIN1,EFCAB11,RPAP1,CABLES2,LMAN1,AHCYL1,TOP1MT,STRAP,SPSB3,ZNF583,SNX25,ARHGAP17,POLR2G,ZNF780B,PPT1,NUP155,DCLRE1C,MRPS14,RHBDF2,SUGP1,RBL1,FASTK,STK38,AP1S1,SPRYD4,H3F3A,CHID1,SMAD4,RAD51D,SLC30A9,UNK,CMAS,NADSYN1,HMGN3,NCAPG,SCYL2,FZD6,HERC3,GTPBP3,CTSS,ORC3,RNLS,YTHDC1,ACP2,HMGN5,CSRP1,METTL5,ABCF2,TUFM,RANGAP1,PNPLA8,HAGH,API5,ZFR,SEC23IP,E2F1,TMEM219,USP20,RBPJ,PDCD6IP,MAX,LUZP1,ADAM10,CXXC1,TSC22D3,AP3M2,CUL1,GYG1,NANS,OAT,MYEF2,ANKRD26,PA2G4,NOL11,FIZ1,ZNF200,MARCH2,SLC26A2,SRP72,KLF10,LACTB,RFC2,CBFB,RAB2B,MAP3K4,HHEX,LUC7L3,RPS14,MAP4,MRPL27,BTF3,PTPDC1,NMD3,CCDC59,PTOV1,COX5B,DNAJC5,SCOC,DHPS,POLR2K,ANKH,VAV2,C16orf87,PRKAA1,GSPT2,DLGAP4,PXMP2,PRPF39,PSEN1,ZNF79,PDXDC1,VPS25,NDUFS7,YY1AP1,C12orf10,FAM192A,RPN1,LHX8,ARPC5,ZNRF2,TPST1,DAPK1,PIK3IP1,CYC1,SOCS5,FDFT1,PIGT,EMB,WDR1,ZNF574,C1orf35,EXOSC9,ARID1A,PTTG1IP,C9orf40,FXR1,GOSR1,MAP2K2,TWISTNB,AKAP1,XRCC5,HMGN2,PI4K2A,CAT,SEC31A,DERL1,MTHFD2,HSPBP1,CEBPG,ARAP1,USP32,FAM83D,CABIN1,SMPD4,GPI,CYTIP,TP53RK,REPS2,RAB11B,UROD,SLC39A13,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C25A1,PAQR6,CSNK1G2,TELO2,ADAM17,HMGN1,NASP,ASPM,PRKAR1B,SYMPK,TARS,SNRPA,MAPK3,HSPA1B,HLA-B,ATAD2,PLAA,ZNF330,OSBPL8,KBTBD7,PREPL |
| 2.484e-14 | -31.33 | biliary_tract-bile_duct-carcinoma-adenocarcinoma | COSMIC cancer mutations | biliary_tract-bile_duct-carcinoma-adenocarcinoma | 15555 | 2418 | 17385 | 2587 |
HECA,ZBTB10,ABCC10,HEXB,CCNL2,FBXO22,EEF2K,RAD23B,ATP13A3,DNM2,ZNRD1,FTSJ3,USP34,ERCC1,NRAS,EHMT1,KIF15,HNRNPF,WDHD1,MIER2,DIDO1,MCM2,RAB22A,SMAD2,MID1IP1,RPS27A,OGT,MPV17,COX5A,SMAD1,ZNF75A,ANXA11,SLC25A33,SEC61G,GGA1,MUM1,TRIO,CUTA,RAB23,KCTD17,HAUS4,EIF2AK4,APH1B,CDC73,MYL6B,ATG4A,TMEM179B,PDXP,SMC3,GEMIN4,MVP,NUP85,PABPC1,NSUN4,PPA1,IFRD1,AGGF1,FOXK1,RBM42,GTPBP4,MAP7D1,MRPL16,ELK1,EIF4H,RDH11,MAGED2,KPNA1,ETS2,TYW5,WIPI2,RUFY3,PDLIM5,ACSF2,EXOC3,RHOG,STARD7,C5orf30,VTI1A,SLC35B2,INO80E,RCOR3,LCLAT1,CPNE3,KIAA1147,RBM23,ZNF420,AHCTF1,TBC1D22A,TBC1D14,GMEB1,NSFL1C,SEPT11,GPD1L,ZC3H3,ARL5A,PDCL3,SNX8,ERMP1,EID1,IDH3A,POLR2D,HTATIP2,MEF2D,TMEM147,GSTCD,TANC1,MAT2A,VPS26B,CORO1C,NSMCE2,CAMKMT,PPP5C,PITRM1,TUBB,COMMD10,ZNF445,SRSF6,HABP4,CCM2,FLOT1,BTN3A1,ATG2B,ABHD14B,PPP1R3B,ZBTB45,HUWE1,ZNF260,NAA50,ANXA5,LTN1,UBE3B,NAP1L4,ZNF710,ST8SIA2,SPTAN1,STAU1,DDX24,TACC1,MRS2,LDHA,HEBP2,LLPH,RAB3IP,TTC33,PICALM,SH3BP5,SLC19A1,ACOX1,FAM3C,AEN,PARP10,YWHAH,THAP5,GPATCH4,FAM129A,TRIM11,YTHDC2,SNX15,RBM8A,ENSA,NENF,SND1,RUFY1,TRIM65,ZER1,PRNP,KRR1,RAB8A,NUP210,NT5DC1,NOC2L,EIF5,TACC3,VPS13B,PTPN18,MIOS,SNRPB,MBLAC2,CDC6,UTP3,PBRM1,ODC1,USP21,TRAM2,FBXO28,BCL7C,ARRDC1,ADAM9,DVL1,NUMB,ZNF564,FUBP1,C1orf74,PARP12,ZCCHC9,CENPF,LAMTOR3,CHCHD2,NCKAP1,LYRM2,RSAD1,TNS3,SUB1,RINL,SSBP3,KIF13B,MBD2,XPA,AHCY,RBM3,LRSAM1,HDHD2,NTPCR,NSDHL,AMD1,CAMSAP1,ZNF761,METTL22,ICAM2,STYXL1,APPL1,BBS12,RXRB,SDHB,PCM1,GALNT2,TMEM168,NLRC5,RUVBL2,BTBD10,MYO9A,CCNB2,USP7,GLT8D1,RPLP2,SUCLG1,ARID2,TMX4,SLC2A1,ATP6V1B2,PCBP1,LYN,BCAP31,VAV1,TMEM69,MRPL50,PSMA6,ZNF473,BRPF3,TARDBP,BCAP29,CTDSP2,PRPF19,PPIF,KDM3B,MND1,CLCN3,BIRC3,RAB7A,ANKRD33B,PPIE,CHMP2B,VDAC1,EIF3H,TMEM201,GLOD4,IDE,DHX16,UHRF2,XRCC3,CHMP4B,PARD3,BCL2L12,C19orf53,MCM10,KLHL21,PDAP1,TMX3,CDCA8,ARF1,SLC12A9,TUBGCP2,DNAJB9,HOMER1,POLR1B,RNF5,RBM15B,PPAN,RHOA,RPRD1A,BTAF1,TOP3A,ARHGEF12,PCGF1,DDX23,RAB18,CACNB1,TRIM26,PDCD6,ATP6V1D,L3MBTL3,FAM110A,NEIL3,CTBS,BBX,IMPDH1,TAF12,NR2F2,PGAM1,HIPK3,IFI16,TXN,NUP188,H2AFZ,PRKCSH,USP39,UBE2I,PARK7,SLC25A37,ASPHD2,ZNF428,TRA2B,SUCLG2,CISD2,TAF5L,SMARCE1,ZNF800,CDC5L,ZNF524,SGCE,OSBP2,NSUN2,USP22,CLNS1A,EIF3A,ZMYM3,DOT1L,IWS1,ANKRD10,WAS,KIF18B,TPP2,C1orf109,ZMAT3,B4GALT2,PRPF38B,RECQL,C9orf78,EWSR1,GADD45G,RRM1,ACAP1,B4GALT1,CYCS,FAM136A,SUPT7L,TMEM165,CNOT3,WDR48,SPAG5,RTKN,CEP104,EXOSC7,KLHL5,LRRC8D,PPP4R1,MSH2,PIGG,FBXL7,OSTF1,MRPL40,TNRC18,SYTL3,FAM171A1,APOL1,EIF5A,GCC2,PRIM2,ELL2,RDH10,MFNG,RPS24,GORASP2,CAPZA2,ADRB2,CCT8,MTR,PHF6,PFDN5,SLCO4A1,TTC13,GOLGA2,RBMX,PIAS2,APPL2,SAMD8,NUDT3,CDKN2A,ZNF511,ATXN3,RAF1,KIAA0232,C2orf49,EPM2A,CD320,CCNA2,MTMR4,BRI3,TP53BP2,AQR,RBM12B,ILKAP,CDK12,SAP30,BRD4,DRAP1,NARF,LRRC8A,ELP4,ABHD11,PKMYT1,ASB13,SERP1,TRIM28,SUPT16H,EIF3K,CHMP4A,ATF6,XRCC4,PRPF4B,ADAM23,NDUFS1,DEPDC1,MECP2,SECISBP2,HMG20A,WWP2,SLC25A36,JAKMIP1,DNAJC8,AXIN2,CITED2,JMJD4,ANKRD37,KAT2A,TMEM126B,RABIF,ADSL,PACS1,BMS1,KCNQ1,ARSK,MACF1,KIF11,KLF6,COMMD4,SMAP2,FADD,SH3GLB1,MYO1F,CBX3,TMEM127,INF2,PPP1R11,DUSP11,DDX5,WDR62,TAF6,ESPL1,PURA,DDB1,DEF6,FAM83G,IPO4,UBL3,PIGM,NAT9,LYRM4,GPR132,UBE2Q1,PTP4A3,BRIX1,MRPL19,ZNF696,SF3B2,PCYOX1L,CDC42,GOT2,JAZF1,HADHB,RPF2,SLC35C2,CNNM3,CARM1,SRPK2,WDR41,LARS,ZCCHC10,CCDC138,LRBA,SUMF2,KMT2C,OGFR,PRPSAP1,ASF1B,RPL37,MAN2A2,EIF4ENIF1,NIP7,U2SURP,MIA2,ATP6V0E1,PPP1R2,PM20D2,XPNPEP3,RGS2,LYAR,FAM89B,POLR2I,TRAFD1,SUGP2,GBA,SYVN1,DAPK3,ARHGAP15,MASTL,UAP1,NFIL3,FN3KRP,YWHAZ,CTSA,TMEM14A,TOB1,TSEN15,ADNP2,TCF12,PRKAB1,MDH2,SMARCA4,ORC1,RRN3,UBXN2A,IARS,CD3EAP,KIF14,EXOSC1,CS,CLTB,DNAL4,CSTF1,POU2AF1,UBQLN4,NXT1,HPDL,PGGT1B,SELPLG,SMU1,ATXN1,GLO1,OGDH,BICD2,CADM1,EDEM2,HERPUD2,TOLLIP,FANCE,MBD3,PDHX,RPS9,ALKBH6,SURF4,DUS3L,ARNTL,ANP32E,FKBP5,TMEM101,CCDC125,ABCA1,PDCD2L,GCLM,RAE1,NUP54,CHIC2,PAWR,MXD4,DCUN1D4,PIP4K2A,XPR1,KIF5B,KLHL20,SEC24C,RRBP1,ARHGEF2,LDLRAD3,STAT3,MYO5A,NIPAL3,AMPD2,TXNL1,PHF20L1,DCAF6,FAM49B,TMEM39A,ATP2C1,RFFL,COG1,RCOR1,PRMT2,TFEB,LEMD2,UPF1,ELMO1,ZC3H7B,DTX4,ZMIZ1,TERF1,HRAS,CCDC93,FGFR1OP,TMED7,PIGQ,AGPAT1,CNTROB,PPP1R16B,MIS12,GSDMB,TTC9C,PDS5B,NUP153,SENP1,PGAP2,TMEM115,DCUN1D5,PLEKHF2,BRMS1,PWWP2B,TRIM47,WDR11,AXIN1,SMG9,TRIM52,LONP2,NDUFV2,PHF23,CERK,SLC4A2,EZH1,ITGB5,LMNA,MCTS1,DDX56,EIF2S2,SLC38A5,FOXN2,CARS2,PRRC2A,C16orf72,RB1CC1,ZMYND11,PGS1,MYBL2,UHRF1BP1,SRSF5,MPG,MATR3,CYB5A,NCDN,POLR2J,SETD3,PTAR1,CNOT6,NDE1,EGLN1,ZNF207,ANKRD27,ABCA3,IVNS1ABP,RMI2,MON1B,TMEM97,NIT2,NUF2,ZNF267,TCF19,TMEM161B,KTN1,APP,PRKD3,CLUAP1,ATP2A2,UTP18,DUT,ZCCHC2,ANAPC7,RNF19A,FAM76B,CLN6,TMEM9,GCC1,RNF169,ADCY7,ATP6V1G1,ENPP4,RNPS1,CDCA2,FKBP3,GPR137,DDX17,CHCHD3,PEX5,CDC16,HIPK2,MBOAT1,TICAM1,ZBTB11,ANXA6,TMBIM4,GMCL1,UBE4A,IL21R,ETS1,WRB,ZNF92,PNO1,CAPN2,ADD3,SUV39H2,TTLL12,TPCN1,TMX1,LYPLA2,HNRNPM,LDHB,PPP3CA,NUDT8,POLK,JTB,EMP3,MTMR12,ZP3,PDE3B,KIF18A,CCDC6,WNT5B,MAPK6,C4orf46,LY75,SLC25A19,RGL1,PSAP,WDR76,IGBP1,FAF1,SNAPIN,COX15,THOC1,AGRN,GNPDA1,GPBP1L1,PPP1R15B,CSNK2A1,EBNA1BP2,GIT2,BIRC2,ATPAF1,DLG5,ABL2,XRCC2,ZFYVE27,MCMBP,PTPRK,CDC37,SP3,METTL1,EXOSC6,HARS,GMFB,ESYT1,ANLN,RAB5B,RHEB,DPYSL3,TBC1D17,TIMM13,CDCA4,TONSL,NRM,NAGLU,ACTB,ZNF45,TMUB1,CTCF,ASAH1,DOCK11,CRLF3,LRRC14,NUS1,SLC27A4,AFF1,MDFIC,MAML1,CYTH1,NQO2,UTP15,EIF2AK1,EIF4G2,ZDHHC3,MOSPD3,ITPRIPL1,CDC27,SNAP23,TBPL1,PRMT7,KCTD7,NDUFA5,CYLD,UGP2,DYNLL1,COPE,HCFC1R1,ZADH2,GGPS1,RAD23A,PDK2,ATP6V0B,STRBP,DUS4L,MRPL34,PDCD2,SAP30L,SLC39A9,CLPTM1,RPL29,RPL35,BTG2,DNAJC9,MTMR6,FRAT2,NFATC2,KDM1B,ARL5B,USP36,CCDC127,MRPL2,ATP1A1,CLK3,PSMD3,MAFK,CEP55,NDUFA11,DNAJC17,ZNF436,NCOA1,SLC25A39,ZC3HC1,ZNF146,ATXN7L2,CDC40,GOLIM4,SMAP1,RRP15,DAP,GNE,SMC6,ARFIP2,NKRF,CHAC2,BZW2,WRNIP1,SS18L1,CENPM,PTGES3,CAMK2G,MLEC,ZNF202,PPWD1,FAM50B,RHOT2,NEU1,TPD52L2,GOLGA7,TWSG1,GLG1,PGRMC1,FAM126A,RPS6KC1,UBE2C,PPCS,NDUFB6,TMEM41B,ZDHHC8,PLXNA1,CCNB1,SLC20A1,COMMD6,ABHD14A,POLR3K,C14orf119,ASAP2,SNUPN,TFG,PLCL2,SEH1L,ATG9A,PBK,MKI67,DDX20,AMDHD2,SLC17A5,GALNT7,CCNF,FOXRED1,PTER,WDR4,DHTKD1,TRAF5,HDAC2,PWWP2A,HSPH1,MAPRE1,CHTF18,ADO,KIF23,SLC35B1,NOTCH2,JMY,FKBP1A,SLC31A1,SNX18,ATIC,ATP6V0A2,PIKFYVE,RNF135,LPCAT1,EEF1D,TMED2,PHF10,FTL,DDX28,ZNF84,SIGMAR1,PIP4K2C,RIT1,PLEC,KDM3A,SF3A2,FAS,EPRS,ZNF777,TMEM54,QARS,PPP3R1,TCOF1,CABLES1,NRBP1,DNMT3A,RWDD1,CKLF,TRIP10,SF3B1,CAST,SUZ12,RPS6KA1,RAC1,GPR89A,OLA1,SNN,GNB2,FLAD1,APLP2,KDM2A,CDKN1B,TNPO2,TALDO1,GPX4,ATP13A1,RFC3,MAPRE2,ERF,CUL3,SLBP,H2AFV,GAR1,PSMB9,POLG2,DHX57,NSA2,HSPA4,MRPL55,JAK1,TBL3,SEL1L,H2AFX,KLHDC4,B4GALT3,PDCD11,ATMIN,POLQ,POU3F2,OTUD5,NCOR2,ANKRD13D,PKP4,SCAMP3,CDCA3,SLC25A12,BLM,TMCC3,GTF2F1,RPL17,CRAT,AHSA1,PRC1,UPF2,COPS7B,SLC38A10,CNPY3,UBE2M,IFT46,TMEM160,TSHZ1,ZFP64,DENND4C,WDR18,RPL8,ILF3,LRRC1,RHOT1,TSR2,MARK2,ECH1,PRDX1,PLD3,NUCB1,GNA12,FBXO21,C1orf131,PRDX3,PFDN4,HNRNPH3,TFDP1,STX18,KHSRP,ASNA1,CPEB2,SSSCA1,VPS29,BYSL,S100PBP,MIB2,IER2,PTMS,NOP2,UBN1,NF1,DCAF15,ALKBH5,MOGS,TAF6L,MAPK14,BECN1,SNAPC4,RNF103,BCAT2,MBD4,C18orf32,METTL14,ZNHIT6,IMPAD1,RCSD1,PHTF1,SRI,KIF22,ZBTB22,NFU1,OGG1,TRIM14,ELOF1,COPS8,FYTTD1,TRIM8,RRM2,SOX4,ABHD5,CXXC4,UBTF,PAF1,UEVLD,SPATA2,PQBP1,IARS2,ATXN2L,GALNT10,STARD3NL,RPS15,PIGN,AGTRAP,CIB1,XPO7,SRRT,ZNF449,CAPZA1,GLTP,KIFAP3,BCL2,N4BP2,HP1BP3,THNSL1,ISG15,CAND1,GNAS,TSC1,RBM25,CDCA5,ZFP90,NANP,RBBP4,ZBTB24,SMARCD1,MBD1,WASF2,MMACHC,TOMM20,IFI27L1,GNPNAT1,MPHOSPH8,HNRNPUL2,CHD1,MEAF6,C2orf68,CCDC50,AKAP8,PARL,RPN2,CHTOP,FAM3A,F2R,SCYL3,TMEM14C,ABI1,HTRA2,MOSPD1,RLIM,FAM172A,ZNF500,PSMB7,NLN,WIPF1,BOLA1,BUD13,NDUFB1,PEF1,EIF3G,BTBD1,TAB2,CHCHD1,TULP3,WDR59,CANT1,SCARB1,GAS2,USP11,SMURF1,PPP2R2D,TSPAN5,CDS2,MAGEH1,MRPL42,EYA1,CDK2AP2,MRPS26,LETMD1,KLF13,HDDC2,RGS1,MAN1A1,FBXO5,GART,TANK,BRD7,MRPL11,SAMD4B,ZDHHC18,GTF3C6,POLR3GL,WDR81,MEN1,ZNF407,MFN2,COX8A,ZRANB2,SRSF3,MBD6,ATP6V1C1,IDH3B,TATDN1,TSC2,LACTB2,CMTM6,RBM4,ZNF275,RPL23A,CDKN2C,USF1,MECR,AP1M1,UPRT,CRY2,ECD,RNF26,TIPARP,LRRC59,ANKRD9,RHBDD2,MGAT5,BAK1,ZNF559,RHOBTB3,GABPA,WBP1,NUTF2,ARF4,GINS4,KRIT1,BOLA3,AHNAK,RAD18,PDRG1,RNASEL,CHPF2,OAZ1,SMNDC1,PDCD4,NXT2,HIVEP3,KIAA0100,CLSPN,RHOC,DHX9,PDCD7,PSMD9,HAUS2,COPB2,CD59,TFAP4,RNFT1,RIMS3,EFTUD2,FBXO7,CPSF4,MRPL21,PHKG2,LUC7L2,SRSF11,EIF3L,MTA2,TYW1,USP10,ITM2A,SSR2,BCLAF1,MTX1,SFXN5,FNTA,PDLIM1,TMEM159,MRPL3,ALS2,FAM72A,TRIM41,KARS,NQO1,POC1A,ANK3,PTTG1,TPX2,TBC1D13,DAZAP2,STMN1,C19orf48,REPS1,ABHD16A,FBXL6,SH3BP1,MTA1,UBA5,CLCN6,INTS12,C8orf59,RPRD1B,CGGBP1,CPNE1,SEC61B,POLR2L,FAM118B,GOPC,E2F3,CIRBP,RPL38,CRNKL1,PFKFB3,GORAB,RAB1A,GIGYF1,TMEM184C,PPP2CA,KIF2A,CCDC14,LSM6,RNF38,SNRPG,DMWD,USP13,ZFP91,TRMT6,IP6K2,WDR5,SLC25A43,IFT27,PMVK,NEIL2,RRP36,SRXN1,RPA2,PSMD2,CLIC4,PDCD10,CBWD2,COQ4,ITGB8,ARF5,ARHGEF1,FBXL19,TTPAL,UTP20,GPS2,DBI,SSNA1,MRFAP1L1,CD81,TMEM131,WDR13,FANCI,PAPOLA,CREM,FANCL,GLIS2,IL6ST,POP7,SLC44A1,MTPN,ASB6,PLK1,RPP25,SEPT9,CELSR2,RBX1,APH1A,RAD51AP1,CKAP2L,PSMG1,UBE2V1,EAF2,IL12RB1,KRTCAP2,LUC7L,LSG1,NECAP2,C1orf122,TRIM4,AGPAT2,CHD3,ZNF367,E2F4,PRPF4,BEND6,CLN3,DNAJC30,NGLY1,POT1,MYL12B,CCDC137,RMND5A,HJURP,PHB2,DNAJB2,FAM53C,NKD2,SDC2,KLC1,CDK13,ADCK5,COX4I1,DNAJB1,RAB6A,ARID1B,C1GALT1,MLX,UBE2Q2,CCP110,ZNF746,ARL6IP1,CTR9,NIPSNAP1,ABHD2,DCAF8,ACSL3,LDB1,MAP4K3,ARMC8,NMT2,IRF5,RPL36,HAUS8,MBIP,ORMDL2,COX7A2L,ZDHHC7,SIL1,FAM122A,UNC13C,BCCIP,SART1,TRAF7,NDUFAF2,TOR1AIP1,ZNF416,LAGE3,ZFYVE21,TM9SF3,RRAGC,ZNF121,OIP5,NRF1,WDR44,PIN1,EFCAB11,RPAP1,CABLES2,LMAN1,AHCYL1,TOP1MT,STRAP,SPSB3,ZNF583,SNX25,ARHGAP17,POLR2G,ZNF780B,PPT1,NUP155,DCLRE1C,MRPS14,RHBDF2,SUGP1,RBL1,FASTK,STK38,AP1S1,SPRYD4,H3F3A,CHID1,SMAD4,RAD51D,SLC30A9,UNK,CMAS,NADSYN1,HMGN3,NCAPG,SCYL2,FZD6,HERC3,GTPBP3,CTSS,ORC3,RNLS,YTHDC1,ACP2,HMGN5,CSRP1,METTL5,ABCF2,TUFM,RANGAP1,PNPLA8,HAGH,API5,ZFR,SEC23IP,E2F1,TMEM219,USP20,RBPJ,PDCD6IP,MAX,LUZP1,ADAM10,CXXC1,TSC22D3,AP3M2,CUL1,GYG1,NANS,OAT,MYEF2,ANKRD26,PA2G4,NOL11,FIZ1,ZNF200,MARCH2,SLC26A2,SRP72,KLF10,LACTB,RFC2,CBFB,RAB2B,MAP3K4,HHEX,LUC7L3,RPS14,MAP4,MRPL27,BTF3,PTPDC1,NMD3,CCDC59,PTOV1,COX5B,DNAJC5,SCOC,DHPS,POLR2K,ANKH,VAV2,C16orf87,PRKAA1,GSPT2,DLGAP4,PXMP2,PRPF39,PSEN1,ZNF79,PDXDC1,VPS25,NDUFS7,YY1AP1,C12orf10,FAM192A,RPN1,LHX8,ARPC5,ZNRF2,TPST1,DAPK1,PIK3IP1,CYC1,SOCS5,FDFT1,PIGT,EMB,WDR1,ZNF574,C1orf35,EXOSC9,ARID1A,PTTG1IP,C9orf40,FXR1,GOSR1,MAP2K2,TWISTNB,AKAP1,XRCC5,HMGN2,PI4K2A,CAT,SEC31A,DERL1,MTHFD2,HSPBP1,CEBPG,ARAP1,USP32,FAM83D,CABIN1,SMPD4,GPI,CYTIP,TP53RK,REPS2,RAB11B,UROD,SLC39A13,POMP,BCL2L1,DECR1,RALB,SIAH1,ADCY9,LPIN2,MRPS27,SOCS6,TTC3,RNASEH2A,CFL1,ANKLE2,CDC123,OAF,VDAC2,EDF1,EML4,ERC1,ANKZF1,RAD51C,ZNF282,DSN1,DDOST,HINT1,DGCR8,SAFB,HAGHL,FTSJ1,RWDD4,LMBR1,NCLN,BEND3,EYA2,DYNC1LI2,MANBA,SLC41A1,B4GALT5,FAM76A,TKT,CBLL1,ARGLU1,LANCL1,POFUT1,FAM8A1,HEATR5B,HLA-A,EBP,RFWD3,NDUFA2,FJX1,FUT8,BTF3L4,PTPN11,MRPL54,FEM1B,RPL19,CNN2,NDUFA3,MTX2,MSH6,PDLIM2,LONRF3,RFXANK,FBXO9,GUF1,RPL32,ZHX1,NDUFS5,WDR91,HIGD2A,ZBED3,RORB,POLA2,ZNF76,COPA,PHRF1,ABCB10,COMMD5,MAP1LC3B,DST,RAB35,SIVA1,GPATCH1,TCEA1,DRAM2,DEAF1,SNRNP200,LAP3,NCK1,VHL,SREK1,ARHGDIB,PITPNB,HSPB11,BRWD1,PPM1G,SH3GLB2,CRCP,BAZ1B,CAB39,ACBD4,STK11,CLU,CHEK2,ZSWIM3,TSTD2,CHPT1,MRPL13,DCAF5,CAPN1,UBE2D3,NSMCE4A,PPP1R12A,ZCCHC8,GORASP1,UBXN1,NACA,RPL15,PCSK7,THRAP3,QSOX2,TTF1,PRPF18,NUP205,CHKA,MED10,ZRANB1,MCPH1,SLC12A2,ATP6V0D1,CSNK1G3,CREG1,NUDT4,RPL6,VKORC1,SLTM,EVC2,KLHL15,SIAH2,SLC16A1,EHD4,SNRNP70,C11orf1,APOL2,N4BP2L2,SNX27,CHMP2A,CORO7,UCK2,PMS2,UCK1,CLCC1,EXT2,MXD1,USP5,HNRNPA2B1,SAP130,NVL,PPP6C,CYB5R1,ZNF770,EBAG9,RNF25,PCGF6,METTL2A,FAM72B,PON2,HPS5,STAT6,MAPK1,BRD9,TMEM33,NAT14,TRIP12,SHPRH,SCYL1,VPS45,GFM2,SPPL2A,FASTKD3,FGFR3,MZT2A,PPIG,ZDHHC13,TMEM99,H2AFY,NDUFS8,ATG13,ERI3,FBL,FRMD8,SLC35A1,MICAL3,TGFB1,B3GALT6,ELOVL5,HEMK1,TIMMDC1,HELB,PSPC1,MIER1,SCFD2,NDRG3,MTMR3,ACAT1,CENPT,PLOD3,RAB3IL1,RAB14,ADD1,KDM4A,MRPS15,XIAP,DHX8,GLUD1,ANKRD23,PABPC4,CDK5,CALM2,PSMD1,NEK6,NSRP1,RABGAP1L,SRSF4,FNIP2,KCNAB2,PCBP2,MLST8,PLK3,ZNF672,HSDL1,MRPL43,TOPORS,MCL1,PPFIA3,SMC2,ICMT,SLC50A1,STOML2,LIMK1,ZNF689,PRDX5,ATE1,MLYCD,ST3GAL2,ATP6V0C,FBXL3,TFDP2,E2F2,PFKP,AAAS,DDX42,SSRP1,MRPL9,MRPS2,STRN4,TOP2B,ZNRF3,TMED3,DDRGK1,RAVER2,GNS,INTS7,INPP5A,MCM5,PHF14,ZNF326,NAGPA,TIMM8B,ETV3,DHX29,TEX10,MAN1B1,RPS10,CBFA2T2,ABCF1,RHOB,LRRC14B,DTWD1,PTPRF,SCARB2,OSBPL11,CCDC86,DUSP3,SLAIN1,MDH1,HEXA,RNF139,SNX14,ZNF296,TRERF1,UBR2,CHD1L,ACTR3,WDTC1,MYH9,CREBL2,NIPA2,PRKACA,SAFB2,STAM,ARL6IP6,RAB21,SP100,ZKSCAN1,DDA1,NUP107,ANKRD13C,MAVS,CEP63,TMEM136,RBM15,ATF2,DCTN1,SHOC2,PSRC1,MAP4K4,WBP2,ATP6V0A1,DNAJA1,NDUFA7,TAZ,TAF2,SEC61A1,WDR7,RPLP1,CBLN2,RBMS1,FUS,GEN1,LRP8,COIL,LRCH1,GALK1,ZNF786,RPS2,SESTD1,TRAK1,JMJD6,SIKE1,AKT1S1,KRI1,FBXO3,ERH,PPP1R8,PRDM4,GTSE1,GEMIN6,DCP1A,SGCB,S100A6,IMPA2,NUDC,PDPK1,TK1,GUK1,TNFAIP3,GALC,ZNF512,KIAA0930,MRPS10,DDX39A,RPA1,ZNF862,ZNF180,KEAP1,POLE,TATDN2,PITX1,CAPN7,LRPPRC,PML,HMGB2,USF2,ANAPC4,SRM,DDX47,MCCC1,CDC42SE2,S1PR2,CDIPT,SSR1,LIN9,PCNA,ZNF639,PIK3R2,ETV6,PPCDC,TXLNA,FAM86C1,MYBL1,MRPL32,CCAR1,ABCC5,PBXIP1,BAZ2A,TLK1,MRPL12,EZR,LNX2,LRP5,BRCA1,PRKRA,STX16,EPB41,OPTN,SEPT1,SOCS4,QRSL1,GLCCI1,NUDT11,GEMIN7,SEPHS2,LZTR1,RACGAP1,PPP3CB,B4GALT4,RLF,RAPGEF6,SNRNP25,RB1,VASP,MED8,VMP1,PPIL2,MEA1,TIMELESS,AHDC1,ALDH18A1,TMEM8A,ABCC1,PREB,TRAPPC9,AACS,MEMO1,KRAS,RTF1,UBE4B,NFATC2IP,LY6E,ARPC1A,ZNF174,PSMC4,GOLGA4,SYNCRIP,PALB2,PRPS2,NIPA1,TIGD2,RNF114,FOXM1,MRPL39,XAB2,SUMO2,DUSP22,COMMD8,RPL11,CSDE1,MDM2,CORO1A,METTL9,MINPP1,DVL2,GM2A,PSMA8,COQ10B,CPOX,TIGD5,SLC26A6,CYP20A1,PRPF3,TXNL4A,RPSA,SRSF1,DNAJC10,SCAP,ZNF700,PLEKHG4B,TIMM17A,FAU,LTA4H,AP2S1,USP53,INTS2,CTDP1,MIF4GD,CDT1,ARID5A,SUMF1,GGA2,AP3S1,CSNK1A1,RMI1,TFRC,PTPN2,STARD9,IRF4,GSTK1,NDUFV1,SLC1A4,CWC27,SLC35B4,DDX31,ABCD1,RPAP3,CNTN5,SNX2,ZMYM5,CCDC34,CHCHD6,BSDC1,KPNA4,CDKN2AIPNL,FBXO41,BIRC5,TFE3,SNAP29,CDCA7L,PKD2,ACADM,CHMP7,SAT2,GCSH,ZNF496,TMEM109,TAP1,NHLRC3,IKBIP,EIF1B,ELMOD2,KIFC1,DBNDD1,RNASEK,CDC25B,PRADC1,DNMT1,NOL12,ORAI2,AKT2,GNG7,AURKB,MCFD2,SLC25A5,ZFAND5,MAK16,STT3A,TMED10,PSMD8,EIF2D,ITGB1,PTPN7,UQCRH,RRS1,ARRB2,RTN3,SVIP,DDX58,WSB2,PPIB,MUT,GMFG,HLA-E,NDUFA4,MAN2B1,METTL3,CFLAR,NDUFS4,RNF121,MEX3C,KLF16,HDAC7,DAD1,BDH1,PCYT2,GNAI2,TERF2,MORC3,KCTD20,SEPT8,DCTD,TOMM40,ADSS,SERTAD2,SERF2,NSF,DCK,ERGIC3,ACLY,LPCAT4,VCPIP1,YY1,PPP6R3,MAP3K5,PPP6R2,RNF14,CDK2,ZC3HAV1,ZBTB37,URB2,EIF3D,MAGED1,KLHL18,ADPGK,SLC25A44,AP1B1,SDHA,PAIP2,PHC2,CRKL,MOAP1,TERF2IP,CYHR1,ZNF75D,SHC1,UCHL5,NAA35,TMBIM1,CCT2,CDKN2AIP,MKLN1,HMGN4,GALK2,CDC23,SHCBP1,AP4E1,PRDM11,VEZF1,PPP2R5A,ACYP1,STAT1,PPA2,TRIM32,RHEBL1,C1orf112,TCF3,MRI1,BRAP,AGPAT3,MYNN,SDF2L1,SPR,RAB11A,REEP5,FOXO3,MAD2L2,CCDC28A,PIP5K1C,RBM17,MAT2B,PTEN,CENPJ,TAGLN2,OSTC,CREB1,PACS2,NCOA2,SMC4,RNASEH2C,NEK7,NET1,PARP4,TBRG4,ANAPC2,RPL27A,YIF1A,SGSH,HGS,TTLL4,SLC38A7,MFAP1,CCDC69,BRWD3,ESYT2,SKA3,NPHP4,UBE2E2,PLXNC1,ST13,TMEM184B,DNAJC24,ZNF107,KIF2C,SLC29A1,AGFG1,SIRT2,FKBP2,USP48,UBQLN2,SNRPD3,CUTC,EDC3,UBLCP1,ZNF804A,RAP1A,THADA,EIF4A3,AP3S2,ATG3,DPYSL2,PPP1R12C,AKR1B1,NDUFB9,JOSD1,RP2,TTC4,TECR,ARID4A,FGFR1OP2,TIMM50,TDP1,DPM1,FOPNL,SLC16A7,WDR82,SLC25A22,STK17B,DHX15,CHAF1A,GEMIN5,COPS6,SASS6,RPS26,PSMC1,SLC12A7,TBC1D12,TM9SF4,ZNF768,UFC1,MED13L,TIA1,EPHX2,PITHD1,RHBDD1,NFATC3,BANF1,BUD31,ZNF335,YBX1,KNTC1,ACAD8,UBE3C,ZNF189,ALDH9A1,KDELR1,TSTA3,CIC,OXR1,PSMA1,NAP1L1,ODF2,EXOC4,KIAA1328,PITPNA,NAA20,PTDSS1,MZT2B,PDSS2,C7orf26,TMEM106C,IMMT,ASH1L,CHERP,WDYHV1,PLAGL2,CHKB,IRF3,TWF2,PAIP1,ANKRD28,FARSA,SAR1A,SCAMP4,APOOL,PDIA6,ACSL5,TOR1AIP2,AZI2,GFER,RAD54B,DAP3,TMEM41A,ZNF317,GADD45B,AKNA,REEP4,CBX4,MIF,KIF3B,GOLPH3L,SH2D3A,CASP6,TOR3A,SRGN,DBF4,MFSD10,SAC3D1,CTNNBL1,YIF1B,CLDND1,TTC17,SLC25A1,PAQR6,CSNK1G2,TELO2,ADAM17,HMGN1,NASP,ASPM,PRKAR1B,SYMPK,TARS,SNRPA,MAPK3,HSPA1B,HLA-B,ATAD2,PLAA,ZNF330,OSBPL8,KBTBD7,PREPL |
| 2.743e-14 | -31.23 | regulation of RNA metabolic process | biological process | GO:0051252 | 3969 | 756 | 17256 | 2622 |
ZBTB10,KDM4A,HEXB,XIAP,CCNL2,EDRF1,RBM4,ZNF275,PABPC4,CDK5,USF1,PSMD1,CIPC,NSRP1,THAP4,SRSF4,DNM2,CRY2,FNIP2,ECD,SENP1,PLK3,ZNF672,ZNF559,AATF,GABPA,EHMT1,HNRNPF,WDHD1,MIER2,TOPORS,ARF4,BRMS1,BOLA3,AHNAK,SMAD2,RPS27A,ZNF689,AXIN1,PRDX5,OGT,VIPAS39,RNASEL,TRIM52,TFDP2,SMAD1,E2F2,ZNF75A,PDCD4,ZNF720,SSRP1,HIVEP3,DHX9,EZH1,EIF2AK4,PSMD9,PARN,CDC73,MCTS1,DDRGK1,TFAP4,MEGF8,PHF14,ZNF326,FOXN2,MYDGF,CPSF4,PABPC1,NUP85,IFRD1,AGGF1,RBM42,ETV3,FOXK1,RB1CC1,ZMYND11,MTA2,MYBL2,BCLAF1,SRSF5,CBFA2T2,ELK1,PDLIM1,ETS2,SETD3,CNOT6,SGF29,EGLN1,ZNF207,RHOG,ZNF296,KARS,SARNP,TRERF1,IVNS1ABP,UBR2,PTTG1,WDTC1,CREBL2,ZNF267,INO80E,SAFB2,RCOR3,TCF19,APP,AHCTF1,ZNF420,SP100,ZKSCAN1,MTA1,GMEB1,NUP107,ZNF226,MAVS,ATF2,RBM15,ZC3H3,RPRD1B,CGGBP1,CPNE1,PSRC1,POLR2L,EID1,KAT7,WBP2,RNPS1,CIRBP,E2F3,HTATIP2,MEF2D,DDX17,TAF2,PPP2CA,CHCHD3,HIPK2,TICAM1,FUS,ZBTB11,LRP8,USP13,COMMD10,ZNF786,ZNF445,SRSF6,ZFP91,HABP4,TRAK1,JMJD6,GMCL1,ABHD14B,WDR5,ETS1,NEXMIF,ZNF92,ZBTB45,PSMD2,SUV39H2,PPP1R8,PRDM4,ZNF260,DCP1A,ZNF710,GTF2H2,MED22,PDPK1,PPP3CA,TNFAIP3,ZNF512,ZP3,PICALM,ZNF862,ZNF180,KEAP1,GPS2,PITX1,LRPPRC,PML,HMGB2,CD81,PARP10,IGBP1,USF2,YWHAH,THAP5,FAF1,AGRN,THOC1,AAMDC,GPBP1L1,TRIM11,RBM8A,CSNK2A1,SND1,BIRC2,PAPOLA,CREM,PRNP,LIN9,TET3,PCNA,GLIS2,ZNF639,ETV6,PIK3R2,NOC2L,MYBL1,MTPN,CCAR1,RYBP,PTPRK,PLK1,SP3,EXOSC6,CELSR2,RBX1,PBXIP1,BAZ2A,ZBED5,MRPL12,EZR,CDC6,UBE2V1,LRP5,PBRM1,EAF2,BRCA1,USP21,TONSL,CHD3,ZNF367,E2F4,DVL1,ZNF45,BEND6,FAM208A,ZNF564,FUBP1,LZTR1,PHB2,CENPF,CTCF,CHCHD2,CDK13,DNAJB1,PPP3CB,RLF,ASXL2,CNOT11,CRLF3,ARID1B,LRRC14,SUB1,RB1,MLX,MED8,MBD2,SSBP3,ZNF746,CTR9,TIMELESS,MDFIC,AFF1,ICE2,MAML1,PREB,TRAPPC9,LDB1,UTP15,KRAS,RTF1,ZNF761,NFATC2IP,RBM38,IRF5,ZNF174,PSMC4,RXRB,SYNCRIP,NLRC5,TBPL1,PRMT7,RUVBL2,USP7,CYLD,TRAF7,ARID2,FOXM1,DYNLL1,ZNF416,DUSP22,PCBP1,COMMD8,ZNF121,VAV1,CSDE1,NRF1,ZBTB21,PSMA6,ZNF473,MDM2,KMT5C,ZNF302,PIN1,TARDBP,AHCYL1,STRAP,SAP30L,ZNF583,DVL2,PRPF19,KDM3B,POLR2G,ZNF780B,PSMA8,BTG2,PPIE,NFATC2,KDM1B,USP36,SRSF1,SCAP,ZNF700,RBL1,CLK3,MAFK,FASTK,PSMD3,ZNF436,UHRF2,DNAJC17,NCOA1,H3F3A,SMAD4,ZNF146,BCL2L12,SLC30A9,CTDP1,MTERF1,DAP,CDT1,AGO2,ARID5A,GTF3A,HMGN3,NKRF,CDK11B,PAGR1,FZD6,PTPN2,IRF4,SS18L1,RBM15B,YTHDC1,RPRD1A,RHOA,HMGN5,BTAF1,PRKDC,ZNF202,ZMYM5,PCGF1,TRIM26,BIRC5,TWSG1,L3MBTL3,TFE3,CDCA7L,BBX,E2F1,PKD2,RBPJ,TAF12,NR2F2,HIPK3,IFI16,TXN,ZNF496,H2AFZ,MAX,TSC22D3,CXXC1,YTHDF3,CCNB1,UBE2I,COMMD6,PARK7,MYEF2,GLMP,PA2G4,NOL11,FIZ1,ZNF200,TRA2B,TAF5L,SMARCE1,DNMT1,ZNF800,CDC5L,SRSF10,ZNF524,KLF10,ELOA,DDX20,SUPT20H,AURKB,USP22,CBFB,ZMYM3,IWS1,DOT1L,HHEX,BRD2,PSMD8,RPS14,BTF3,ARRB2,TRAF5,NMD3,CCDC59,HDAC2,PTOV1,DDX58,HSPH1,EWSR1,POLR2K,PRKAA1,NOTCH2,PMF1,SUPT7L,PSEN1,ZNF518A,ZNF79,METTL3,VPS25,CNOT3,JMY,YY1AP1,CFLAR,EXOSC7,LHX8,KLF16,HDAC7,TNRC18,EEF1D,TERF2,PHF10,ZNF84,ELL2,ZNF574,USF3,EXOSC9,ADRB2,ARID1A,FXR1,C9orf40,KDM3A,MAP2K2,PSMB3,PHF6,XRCC5,CAT,PFDN5,ZNF777,SERTAD2,EPOP,ZFP92,RBMX,QARS,MED15,CEBPG,PPP3R1,PIAS2,YY1,MAP3K5,RNF14,CDK2,ZC3HAV1,CDKN2A,ZNF511,DNMT3A,ATXN3,RWDD1,ZBTB37,RPS6KA1,RAF1,SUZ12,MAGED1,TERF2IP,SPINDOC,CCNA2,ZNF75D,SHC1,KDM2A,UCHL5,LPIN2,CDKN1B,CDK12,SAP30,BRD4,ERF,DRAP1,CUL3,ELP4,EDF1,H2AFV,PSMB9,TRIM28,ERC1,CENPU,PRDM11,SUPT16H,VEZF1,ZNF282,HINT1,CERS6,SAFB,STAT1,H2AFX,ATF6,TRIM32,BEND3,EYA2,ATMIN,RHEBL1,POU3F2,NCOR2,DEPDC1,MECP2,TCF3,SECISBP2,MYNN,ARGLU1,BLM,POFUT1,FOXO3,HMG20A,MAD2L2,WWP2,GTF2F1,RBM17,CCNK,PTEN,ELP5,AXIN2,CARF,CITED2,CREB1,CNOT6L,NCOA2,TSHZ1,ZFP64,KAT2A,ILF3,RFXANK,TBRG4,KLF6,COMMD4,FADD,POLR2A,CBX3,PRDX3,ZHX1,TFDP1,KHSRP,DDX5,BRWD3,TAF6,PURA,FAM83G,RORB,ZBED3,CCNC,ZNF76,IER2,NOP2,HNRNPAB,UBN1,KMT2E,PTP4A3,ZNF107,SIRT2,TAF6L,COMMD5,MAPK14,SNAPC4,ZNF696,JAZF1,METTL14,PHTF1,SRI,ZBTB22,TCEA1,OGG1,ARID4A,CARM1,TRIM14,ELOF1,SRPK2,DEAF1,TRIM8,NCK1,VHL,RIOX2,SREK1,RRM2,SOX4,KMT2C,ASF1B,UBTF,PAF1,BRWD1,PQBP1,BAZ1B,ZNF268,CHEK2,CLU,RPS26,PSMC1,UBE2D3,PPP1R12A,ZNF768,NACA,CIB1,MED13L,TIA1,MEF2A,THRAP3,TTF1,SRRT,LYAR,NFATC3,ZNF449,MED10,BUD31,ZNF335,YBX1,ACAD8,MCPH1,ZNF189,HP1BP3,VOPP1,CREG1,ERLIN1,CIC,RPL6,PSMA1,EIF2A,SLTM,DAPK3,CAND1,RBM25,NFIL3,SIAH2,NUP62,YWHAZ,ZFP90,SNRNP70,RBBP4,HNRNPDL,TOB1,N4BP2L2,SMARCD1,ADNP2,ZBTB24,TCF12,MBD1,ASH1L,MPHOSPH8,SMARCA4,PLAGL2,NSD3,IRF3,ORC1,CHD1,MXD1,PAIP1,MEAF6,HNRNPA2B1,SAP130,RRN3,EXOSC1,AKAP8,CHTOP,F2R,UTP4,ZNF770,RLIM,CHP1,MOSPD1,POU2AF1,FAM172A,ZNF500,RNF25,SMU1,PCGF6,PSMB7,ATXN1,BOLA1,GLO1,ERBIN,MBD3,ZNF317,TAB2,HNRNPR,STAT6,TULP3,ARNTL,AKNA,SMURF1,MAPK1,BRD9,CBX4,NAT14,DNAJC2,ZNF316,EYA1,SCYL1,KLF13,PAWR,MXD4,FBXO5,FASTKD3,KMT5A,PELO,H2AFY,ANP32A,BRD7,ARHGEF2,STAT3,TGFB1,SAMD4B,PHF20L1,DCAF6,HMGN1,PSPC1,MIER1,RCOR1,PRMT2,MEN1,ZNF407,CDK11A,SNRPA,MAPK3,TFEB,HSPA1B,CNOT9,LEMD2,UPF1,ATAD2,KMT2B,ZRANB2,CENPT,SRSF3,ZMIZ1,HRAS,TERF1 |
| 2.779e-14 | -31.21 | VAPA (VAMP associated protein A) | protein interactions | 9218 | 252 | 90 | 17029 | 2761 |
NDUFA5,IMMT,GPR89A,TAP1,SMARCA4,ATP6V1B2,PRKACA,SYNRG,APP,AHCTF1,NOL11,ATP2A2,CDC42,WDR44,SRI,AP2B1,ZFYVE27,RPN2,ZBTB22,ATF2,ATP6V1G1,OSBP2,VDAC2,TMEM216,NFATC2,NDUFA7,RAB1A,VDAC1,MCM2,RAB5B,LSG1,ARF4,STOML2,CCDC127,EIF3K,CHCHD3,SURF4,ACBD4,PIEZO1,RPS26,RTN3,PARD3,DDX58,NDUFV2,COX5B,NDUFS1,GOLIM4,PHB2,FLOT1,TKT,SLC25A12,COX4I1,XPR1,JMY,HEATR5B,NDUFS4,NDUFV1,NDUFA2,NDUFB4,ABCD1,NDUFS8,ORC3,ATP6V0D1,MICAL3,SLC25A1,EIF5A,RB1CC1,TACC1,ERLIN1,PRKAR1B,MTMR12,ARHGEF12,ADRB2,TOMM40,VKORC1,GOSR1,CHCHD6,NEU1,YIF1A,OSBPL11,NSF,PTAR1,USP20,PITPNA,CTSA,NDUFS5,NANP,CCNB2,FAF1,FAM83G |
| 2.792e-14 | -31.21 | RPL18 (ribosomal protein L18) | protein interactions | 6141 | 244 | 88 | 17029 | 2761 |
CYLD,NOP2,RPLP2,HNRNPUL2,CUL1,EBNA1BP2,BRIX1,PABPC4,RPL11,RPL23A,PA2G4,IARS,EIF4A3,NOC2L,RPF2,FTSJ3,MRPL32,RPL35,NOL8,MRPL12,RPL38,CUL3,RIOX2,BRCA1,UTP3,BUD13,MCM2,SLC25A5,RPS9,RPSA,NSA2,RPS27A,RPS14,MRPL27,RPLP1,FUS,COPS6,RRS1,FAU,ARRB2,MRPL13,PDCD11,RPS26,NIFK,RPS15,RPS2,MECP2,RPL15,ATP5F1B,RPA2,DDX56,HUWE1,RPL17,RBM34,ZNF746,RPL19,MRPL48,NAP1L4,PTGES3,FBL,PABPC1,NSUN4,HNRNPM,EEF1D,STAU1,RHOA,DDX24,ZNF512,GTPBP4,ILF3,RPL8,RPL6,RPS10,MRPS10,RPS24,MRPL16,RPL27A,RPA1,CAND1,RPL36,NAP1L1,FNTA,RPL32,ATP5F1A,CDK2,MRPL3,ZC3HAV1,DDX52 |
| 2.878e-14 | -31.18 | GO_NEGATIVE_REGULATION_OF_CELL_CYCLE | MSigDB lists | GO_NEGATIVE_REGULATION_OF_CELL_CYCLE | 412 | 122 | 17377 | 2626 |
ZNF207,CHMP2A,PRKAB1,SART1,HECA,GPR132,THOC1,TSC2,CAST,PTTG1,CSNK2A1,SMARCA4,CUL1,RRAGC,BCL2L1,CCNB1,PRKACA,FANCI,PRNP,CDK5,DST,CDKN2C,PA2G4,MDM2,PCNA,CCNA2,CDKN1B,TP53BP2,ATF2,CTDSP2,HTRA2,CARM1,PTPRK,MLST8,CDC5L,PRPF19,PLK3,PLK1,TIMP2,BRD4,CDC123,BTG2,CUL3,AURKB,BRCA1,SOX4,CCNF,RHEB,HHEX,RPS27A,E2F4,PPM1G,CAB39,ZNF268,STK11,GAS2,CHEK2,VPS4A,TFDP2,PDCD4,MIF,CLSPN,CENPF,PRKAA1,LAMTOR3,TOP2B,NOTCH2,EIF2AK4,BLM,ETS1,CDC73,MAD2L2,JMY,CNOT3,FBXO5,RPA2,TFAP4,CCNK,RFWD3,RB1,SMC3,PTEN,CENPJ,FBXO7,MSH2,BRD7,GTSE1,H2AFY,BCL2,KNTC1,CNOT6L,MCPH1,TERF2,TGFB1,PPP1R9B,TNFAIP3,HMGN5,PRKDC,TBRG4,MEN1,PRMT2,EIF4G2,MACF1,RHOB,RBM38,MFN2,TSC1,TFDP1,PML,E2F1,PKD2,CNOT6,NR2F2,ZNF830,CDK2,UBE2C,TAF6,TERF1,THAP5,ESPL1,HRAS,CDKN2A |
| 2.943e-14 | -31.16 | GNF2_RRM1 | MSigDB lists | GNF2_RRM1 | 86 | 43 | 17377 | 2626 |
HNRNPAB,FOXM1,CENPF,RRM1,CDCA8,RACGAP1,FANCI,DTL,PA2G4,PCNA,CCNA2,MCM5,KIF14,PRC1,MSH2,CENPM,PTGES3,SMC4,GINS1,RFC3,NASP,ASPM,RAD51AP1,MKI67,SLBP,RRM2,NUSAP1,AURKB,SMC2,MCM2,SHCBP1,KIF11,PRIM1,CHCHD3,KIF18B,BIRC5,H2AFX,ANP32E,HMGB2,SNRPG,UBE2C,CCNB2,SSRP1 |
| 3.551e-14 | -30.97 | GSE16451_IMMATURE_VS_MATURE_NEURON_CELL_LINE_WEST_EQUINE_ENC_VIRUS_DN | MSigDB lists | GSE16451_IMMATURE_VS_MATURE_NEURON_CELL_LINE_WEST_EQUINE_ENC_VIRUS_DN | 186 | 70 | 17377 | 2626 |
SRM,PIGM,THOC1,URB2,RBM8A,PLAGL2,ORC1,SND1,CCNB1,C19orf48,CDK5,OIP5,TXLNA,PDIA6,CLN6,NRAS,NSUN2,GMFB,POLR2D,SMC2,MRPS14,FANCE,PTPN7,RRS1,TSPAN5,SLC25A39,LRP8,SSRP1,CCDC137,TMEM33,HIVEP3,KIAA0100,RAE1,FAM136A,VPS25,POFUT1,XPR1,LYAR,DTL,HOMER1,DDX56,CLIC4,NUS1,SUV39H2,MED8,FUT8,CENPM,ALDH18A1,GTF3C6,MAPKAPK3,TMEM39A,TBRG4,MTX1,TOMM40,ARPC1A,MFN2,HSPBP1,ORMDL2,CCDC86,HNRNPH3,SLC16A1,IMPDH1,SLC25A19,PITPNA,NANP,RNF14,ESPL1,IPO4,SSSCA1,ADNP2 |
| 3.664e-14 | -30.94 | ECT2 (epithelial cell transforming 2) | protein interactions | 1894 | 153 | 64 | 17029 | 2761 |
MBD1,RHOG,IMMT,NPHP4,SKA3,NUP188,SUCLG1,FOXM1,COPE,POMP,CDK5,PSMA6,ATP2A2,SUCLG2,AHCYL1,STRAP,CFL1,CDC5L,SRPK2,PLK1,SNRNP200,PPP1R18,ELOA,VDAC2,WDHD1,RFC2,SRSF1,STOML2,CHCHD3,PPP2CA,RAD18,PPM1G,USP11,MAPK1,CAPN1,PARD3,GALK1,PHB2,RACGAP1,WDR5,AP3S1,COPG2,CAPN2,RPN1,KLHL20,PELO,CAPZA1,CYC1,CPSF4,UBE3C,LPCAT1,MICAL3,LDHB,AGGF1,LDHA,ARID1A,CAND1,XRCC5,PML,YWHAZ,TCOF1,PPP6R3,RNF14,ESYT2 |
| 3.795e-14 | -30.90 | mitochondrial part | cellular component | GO:0044429 | 997 | 235 | 18223 | 2701 |
COX15,LYRM4,MTX3,NDUFB6,MRPS15,UQCR10,MCCC1,GLUD1,ABCB10,LACTB2,CCNB1,OAT,ATP5PF,BECN1,MRPL19,PARK7,SLC25A37,BCAT2,TIMM23,GOT2,SLC44A1,MECR,DNM2,HADHB,SUCLG2,NDUFB9,CISD2,LRRC59,MRPL32,TRIM14,MRPL57,TIMM50,BAK1,MRPL43,MRPL12,MCL1,SLC25A22,COA7,SLC25A5,FOXRED1,MPC1,STOML2,TIMM13,RPS27A,TIMM29,MRPL27,PRDX5,IARS2,MPV17,COX5A,MLYCD,DHTKD1,UQCRH,RNASEL,CLU,DHFR2,MRPL13,SLC25A33,NDUFV2,COX5B,MRPL9,MUT,MRPS2,PHB2,CHCHD2,NDUFA4,COX4I1,CYCS,PSEN1,NDUFS7,NDUFS4,NDUFAF6,TIGAR,BDH1,SLC25A51,BCL2,MRPL40,MRPL48,CYC1,ACAD8,ALDH18A1,MRPL21,MRM3,NSUN4,CARS2,TIMM8B,DDX28,ATP5IF1,COQ8A,NOA1,PGS1,ACSL3,MRPL16,MTX1,MPG,TOMM40,SFXN5,CYB5A,AKAP1,SDHB,CAT,MTHFD2,QARS,COX7A2L,ATP5F1A,NIPSNAP2,TMEM14A,PDSS2,ACSF2,MRPL3,NDUFA5,KARS,TOMM20,ATXN3,IMMT,SUCLG1,NDUFAF2,MRPL39,MDH2,RAF1,STARD7,BCL2L1,SLC25A44,SNN,LYN,SDHA,MIEF1,MOAP1,FLAD1,MRPL50,DECR1,PDK2,SHC1,GRSF1,CS,MRPL34,MRPS27,MICU2,PARL,MAVS,APOOL,TOP1MT,ATF2,TMEM14C,HTRA2,MRM2,PPIF,ACSL5,COQ10B,IDH3A,CPOX,DMAC2,VDAC2,NLN,OGDH,NDUFA7,NDUFB1,VDAC1,TAZ,POLG2,MRPS14,GFER,PDHX,CHCHD3,ANKZF1,MRPL2,DAP3,MRPL55,FASTK,TOMM6,CHCHD1,TIMM17A,NDUFA11,PPA2,PITRM1,SLC25A39,CDS2,NDUFS1,MRPL42,MTERF1,TWNK,MRPS26,SLC25A12,LETMD1,TIMM21,ATP5F1B,SLC25A43,GFM2,FOXO3,SLC25A36,GSTK1,NDUFV1,NDUFA2,COQ4,NDUFB4,CRAT,MRPL54,NDUFS8,MRPL11,CREB1,NDUFA3,STAT3,MTX2,RNF5,SLC25A1,COA3,TIMMDC1,TMEM126B,ABCF2,MRS2,TUFM,MRPS10,NADK2,TBRG4,RHOT1,ATP5MF,HAGH,RHOT2,GUF1,CHCHD6,SH3GLB1,MFN2,ATP5MC3,PRDX3,PARG,COX8A,LRPPRC,NAXE,ACAT1,SLC25A19,NDUFS5,ACADM,IDH3B,GCSH,HIGD2A |
| 3.844e-14 | -30.89 | Transcriptional Regulation by TP53 | REACTOME pathways | R-HSA-3700989 | 367 | 118 | 10287 | 1696 |
USP7,PRKAB1,TP53RK,TXN,TSC2,PMS2,TPX2,RMI2,RRAGC,CSNK2A1,CCNB1,MAPK14,FANCI,MEAF6,CDK5,MDM2,PCNA,CCNA2,ZNF420,BRPF3,PIN1,NOC2L,CDKN1B,TCEA1,TP53BP2,ATF2,CDK12,CARM1,MLST8,PLK3,RFC3,POLR2G,POLR2L,AKT2,BTG2,EHMT1,ELOA,POLR2D,AURKB,BRCA1,RFC2,MBD3,RHEB,SUPT16H,TAF2,PPP2CA,RBL1,CHD3,RPS27A,E2F4,HIPK2,PRDX5,COX5A,STK11,CHEK2,TFDP2,RAD51D,HDAC2,SSRP1,CTDP1,COX5B,CASP6,POLR2K,PRKAA1,AGO2,LAMTOR3,NDUFA4,COX4I1,CDK13,CYCS,BLM,CNOT11,RMI1,PIP4K2A,CNOT3,JMY,GTF2F1,CCNK,RPA2,TIGAR,PTEN,CENPJ,KMT5A,MSH2,BRD7,CNOT6L,GTF2H2,PDPK1,POLR2I,MTA2,TOP3A,PIP4K2C,RFFL,POLR2A,PRDX1,RPA1,FAS,CNOT9,TSC1,POLR2J,BIRC5,COX7A2L,LAMTOR4,TFDP1,PML,LRPPRC,E2F1,COX8A,TMEM219,CNOT6,YWHAZ,GPI,TAF12,RBBP4,CDK2,TAF6,YWHAH,CDKN2A |
| 3.868e-14 | -30.88 | MONNIER_POSTRADIATION_TUMOR_ESCAPE_UP | MSigDB lists | MONNIER_POSTRADIATION_TUMOR_ESCAPE_UP | 372 | 113 | 17377 | 2626 |
SRM,CCDC93,NQO1,MRPS15,URB2,SMARCA4,INO80E,SLC25A44,MAPK14,PABPC4,PA2G4,ATP2A2,RAB35,ETV6,RAD23B,TXLNA,SOCS6,AKR1B1,ZFYVE27,RPAP1,TARDBP,MCMBP,LRRC59,GPD1L,STRAP,FTSJ3,CCAR1,RLIM,MLST8,METTL1,PPIF,APH1A,ANKRD33B,TAOK1,NOL8,MAP4K4,SREK1,PRPF3,ODC1,GEMIN5,HSPA4,ATP1A1,DUS3L,BRD2,SCAP,LUC7L3,PROSER1,C1orf109,RWDD4,PRPF4,TFDP2,SMAD1,SLC22A23,SMURF1,PDCD11,TSPAN5,ZMAT3,DYNC1LI2,ANXA11,INTS2,GCLM,DAP,FAM53C,PDAP1,TRMT6,DHX9,KCTD17,LETMD1,ARGLU1,ETS1,RAPGEF6,MFSD10,TFRC,NPLOC4,MAN1A1,LRRC14,FASTKD3,TNS3,ZNF335,SLC35B4,PTPN11,SLC12A2,ABCC1,TTPAL,AMPD2,GTF3C6,MLEC,KAT2A,NOA1,PGS1,BTAF1,OXR1,MYBL2,BMS1,ZDHHC3,MATR3,MTR,SLTM,NMT2,HSPA1B,AKAP1,SLC19A1,SEC23IP,RBM25,SYNCRIP,CSNK1G1,BBX,USP20,AEN,PTDSS1,ESPL1,FAM83G,IPO4 |
| 4.599e-14 | -30.71 | WEST_ADRENOCORTICAL_TUMOR_UP | MSigDB lists | WEST_ADRENOCORTICAL_TUMOR_UP | 279 | 92 | 17377 | 2626 |
TMEM106C,FGFR1OP,TXN,H2AFZ,PLXNC1,FOXM1,DCAF15,TMEM41B,PTTG1,COPE,TPX2,TMEM97,ENSA,SMARCA4,TBC1D13,KIF2C,CCNB1,SLC20A1,FANCI,PCYOX1L,ATP6V0B,IARS,KIF14,DDA1,RAD23B,RPN2,NAA35,DNMT1,ATP6V1G1,RHOBTB3,ATP13A1,NRAS,CDC123,PBK,NOL8,PSMB7,RRM2,GLO1,BICD2,CDC23,ICMT,VDAC1,MCM2,CHAF1A,DAP3,ATP1A1,KIF18B,OAZ1,WSB2,MAPRE1,POLR2K,CENPF,DCTN2,BABAM1,CDCA3,RACGAP1,MYO9B,DNAJB1,BZW2,EBP,DTL,KIF5B,RFWD3,HOMER1,EIF2S2,MED8,INTS7,PRDM4,PRC1,CAPZA1,TNPO3,CENPM,SMC4,ABCC1,FDFT1,RPAP3,TNFAIP3,ASPM,DDX39A,NEU1,RDH11,CAND1,TPD52L2,EPRS,TSC1,MTHFD2,MAPK6,ACLY,CEBPG,SLC16A1,HMGB2,ESPL1 |
| 4.815e-14 | -30.66 | RPL14 (ribosomal protein L14) | protein interactions | 9045 | 234 | 85 | 17029 | 2761 |
CYLD,NOP2,RPLP2,URB2,CUL1,EBNA1BP2,NENF,BRIX1,MYEF2,RBM4,RPL11,RPL23A,NVL,GRSF1,RPF2,TARDBP,ZNF770,FTSJ3,CDK12,NOL12,FYTTD1,RPL29,RPL35,KLF10,VHL,MRPL12,RPL38,RIOX2,CUL3,BRCA1,BUD13,SLC25A5,RPS9,RPSA,PEX5,RPS27A,RPS14,RPLP1,FUS,RRS1,ARRB2,RPS26,CCDC137,PRPF4B,NIFK,RPS15,RPS2,ZNF768,TCF3,RPL15,ARGLU1,BLM,TTF1,NDUFS4,DDX56,PTEN,RPL17,RBM34,PPIG,ZNF746,DDX31,RPL19,PTGES3,PABPC1,HNRNPM,HP1BP3,STAU1,DDX24,ZNF512,RPL8,ILF3,GTPBP4,TUFM,RPL6,RPS10,RPS24,LLPH,RPL27A,CAND1,RPL36,NAP1L1,RPL32,CDK2,DDX52,ZBTB24 |
| 5.247e-14 | -30.58 | KEGG_SPLICEOSOME | MSigDB lists | KEGG_SPLICEOSOME | 122 | 53 | 17377 | 2626 |
PRPF38B,SART1,CDC40,THOC1,CHERP,SF3B1,XAB2,SRSF6,RBM8A,DHX8,USP39,SNRPD3,PCBP1,PRPF18,SF3B2,RBM17,CTNNBL1,EIF4A3,SRSF4,EFTUD2,BUD31,TRA2B,AQR,HNRNPM,CDC5L,SRSF10,PRPF19,SNRNP200,SNRPB,PPIE,CRNKL1,PRPF3,SRSF5,TXNL4A,SF3A2,SNRPA,DHX15,HSPA1B,SRSF1,DDX23,RBM25,DHX16,LSM6,RBMX,U2SURP,PQBP1,PRPF4,DDX5,SRSF3,SNRPG,SNRNP70,SMNDC1,DDX42 |
| 5.653e-14 | -30.50 | GO_PROTEIN_LOCALIZATION_TO_ORGANELLE | MSigDB lists | GO_PROTEIN_LOCALIZATION_TO_ORGANELLE | 525 | 145 | 17377 | 2626 |
POLA2,NUP188,MTX3,TSC2,BECN1,MIS12,RPL23A,SNUPN,TIMM23,RAB35,TIMM50,SRP72,PLK1,NRAS,TOPORS,AURKB,NUTF2,ARF4,OPTN,PAF1,RPL37,HHEX,TIMM13,RPS27A,RPS14,KPNA2,DVL1,RPS26,LONP2,POT1,RPS15,MAPRE1,SEC61G,PHB2,DHX9,TIA1,RPL15,RAB6A,SUPT7L,VPS25,LMNA,SPAG5,NUP205,RB1,FBXO7,TNPO3,YBX1,PIKFYVE,NUP85,KDELR1,MORC3,TERF2,NAGPA,TIMM8B,GCC2,RPS10,RPL6,RPS24,MTX1,TOMM40,PTTG1IP,RPL36,SCARB2,GOLGA4,PCM1,KPNA1,FAM83D,NUP62,RUVBL2,TOB1,TOMM20,RPLP2,SYS1,TOR1AIP1,VTI1A,BCAP31,RPAIN,RPL11,TERF2IP,MOAP1,MDM2,NUP107,TNPO2,BCAP29,ANKRD13C,F2R,GCC1,RPL29,SEC61B,RPL35,RAB7A,RPL38,TOR1AIP2,NUP155,DNAJA1,TOLLIP,RPS9,RPSA,CHMP4A,PEX5,HSPA4,SEC61A1,CCDC14,TULP3,TIMM17A,ARNTL,RPLP1,CHMP4B,FAU,SMURF1,MAPK1,CSNK1D,RPS2,KLHL21,RAE1,SRGN,DCTN2,NUP54,WRB,RAB11A,RPL17,H2AFY,DCP1A,RPL19,STAT3,MTX2,TGFB1,PPP3CA,TNFAIP3,RPL8,PACS1,RAB3IP,RPL27A,SH3GLB1,MFN2,MAPK3,ATP6V1D,KPNA4,HGS,RPL32,OSBPL8,PML,ASNA1,CD81,IPO4 |
| 5.715e-14 | -30.49 | REACTOME_METABOLISM_OF_RNA | MSigDB lists | REACTOME_METABOLISM_OF_RNA | 254 | 86 | 17377 | 2626 |
NUP188,RPLP2,RBM8A,SNRPD3,MAPK14,PAIP1,EDC3,RPL11,RPL23A,SNUPN,PSMD1,PSMA6,NUP210,EIF4A3,EXOSC1,NUP107,NUP153,SEH1L,RPL29,RPL35,EXOSC6,PSMA8,SNRPB,PSMB7,RNPS1,RPL38,DDX20,NUP155,PSMB9,RPS9,RPSA,CLNS1A,GEMIN5,PPP2CA,RPL37,LSM6,RPS27A,PSMD8,PSMD3,RPS14,RPLP1,SMG9,SNRPG,FAU,PSMC1,RPS26,AAAS,GEMIN7,RPS15,RPS2,RAE1,GSPT2,NUP54,RPL15,PARN,PSMD9,CNOT3,NUP205,PSMD2,EXOSC7,RPL17,ANP32A,GEMIN6,DCP1A,UPF2,RPL19,GEMIN4,NUP85,PABPC1,RPL8,RPL6,RPS10,PSMA1,RPS24,EXOSC9,RPL27A,PATL1,PSMB3,HSPA1B,RPL36,PSMC4,RPL32,KHSRP,NUP62,YWHAZ,CNOT6 |
| 5.905e-14 | -30.46 | nef (p27) | protein interactions | 156110 | 797 | 210 | 17029 | 2761 |
PDCD6IP,TXN,HNRNPAB,COPA,ADAM10,HEXB,XIAP,MOGS,CDIPT,OAT,MAP1LC3B,BECN1,MAPK14,PABPC4,SF3B2,KRR1,CALM2,RAB8A,CDC42,EIF4A3,IL6ST,PIK3R2,SRSF4,AP1M1,DNM2,AP2B1,LRRC59,SRSF10,CDC5L,SRP72,LARS,SNRNP200,NRAS,NCK1,AKT2,ELOA,MKI67,HNRNPF,EZR,SLC25A5,DHX15,ARF4,EIF3A,LIMK1,ITGB1,ACTB,VPS4A,CLN3,TRAF5,GORASP1,PHB2,GGA1,HLA-E,VAV2,DHX9,ACAP1,CDK13,CYCS,DNAJB1,COPB2,CD59,RB1,RPN1,NFATC3,SNX18,YBX1,BCL2,ALDH18A1,GNAI2,ATP6V0D1,PABPC1,LUC7L2,EEF1D,APOL1,EIF5A,FTL,GCC2,ACSL3,RPS10,RPL6,SRSF5,PKM,ICAM2,ELK1,MAP2K2,MATR3,NMT2,FAS,RXRB,EPRS,GOLGA4,MTHFD2,SYNCRIP,GOLGA2,NSF,RBMX,EXOC4,ACLY,CEBPG,ATP5F1A,MAP3K5,EHD4,HEXA,PTDSS1,CDKN2A,EXOC3,WASF2,SART1,RAB11B,RAF1,SF3B1,EIF3D,RAC1,MYH9,IRF3,BCL2L1,AP1B1,PRKACA,LYN,PCBP1,SDHA,CPNE3,BCAP31,CD320,HNRNPA2B1,VAV1,IARS,ADCY9,TARDBP,MAVS,CLTB,ATF2,ARL5A,CFL1,ADCY7,CCT2,RPL29,RAB7A,IDH3A,NFATC2,NUP155,VDAC1,ARL5B,TRIM28,RPS9,SRSF1,DDX17,ATP1A1,HSPA4,SEC61A1,DDOST,HNRNPR,SAFB,STAT1,AP1S1,MAPK1,AP2S1,ABCA1,MIF,RPS2,MECP2,SRSF6,AGO2,NKRF,ARF1,GGA2,AP3S1,RAB11A,SCYL2,TFRC,HLA-A,CCNK,PSMD2,PTEN,RPL17,ARF5,RPL19,STAT3,PACS2,HNRNPM,SPTAN1,LDHB,STAU1,ADAM17,RHOA,PRKDC,PRKAR1B,LDHA,RPL8,ILF3,PACS1,SNRPA,ZFR,HSPA1B,MAPK3,TFEB,DDX23,HLA-B,HGS,UPF1,ELMO1,HNRNPH3,LRPPRC,KHSRP,DDX5,PSAP,CHMP7,CD81,HRAS,IFI16 |
| 6.278e-14 | -30.40 | GNF2_CENPF | MSigDB lists | GNF2_CENPF | 59 | 34 | 17377 | 2626 |
MCM10,HJURP,FOXM1,CENPF,PTTG1,CDCA3,RRM1,CDCA8,TPX2,FANCI,KIFC1,PCNA,CCNA2,PRC1,SMC4,ASPM,KIF15,MYBL2,MKI67,DNAJC9,RRM2,NUSAP1,SMC2,MCM2,CCNF,KIF11,SHCBP1,PRIM1,KIF18B,BIRC5,H2AFX,HMGB2,CCNB2,UBE2C |
| 6.345e-14 | -30.39 | GO_PROTEASOMAL_PROTEIN_CATABOLIC_PROCESS | MSigDB lists | GO_PROTEASOMAL_PROTEIN_CATABOLIC_PROCESS | 263 | 88 | 17377 | 2626 |
ATXN3,UBR2,PTTG1,CUL1,SIRT2,UBQLN2,CCNB1,BIRC2,RNF103,RAD23A,UBXN2A,PSMD1,PSMA6,SIAH1,MTA1,KIF14,RAD23B,SOCS6,NSFL1C,ANAPC7,PCBP2,RLIM,PRPF19,PLK1,SEC61B,PSMA8,RBX1,PSMB7,CUL3,TOPORS,AURKB,CDC23,EDEM2,CCNF,PSMB9,ANKZF1,DNAJC10,CDC16,RPS27A,PSMD8,UBXN2B,AXIN1,PSMD3,ARNTL,RNF38,SEL1L,FBXL3,ARRB2,SMURF1,PSMC1,UBE2D3,TMUB1,DNAJB2,UBXN1,KCTD17,SDF2L1,CSNK1A1,PSMD9,DNAJB9,NPLOC4,WWP2,RNF121,PSMD2,KLHL20,GTSE1,FBXL7,FBXL19,RNF5,ERLIN1,MAN1B1,PSMA1,RFFL,FBXO9,ANAPC2,UBE4B,SYVN1,PSMB3,PSMC4,DERL1,KEAP1,CDC27,PML,SIAH2,UBE2C,RNF139,ANAPC4,FAF1,DDB1 |
| 6.633e-14 | -30.34 | GSE37532_WT_VS_PPARG_KO_VISCERAL_ADIPOSE_TISSUE_TCONV_DN | MSigDB lists | GSE37532_WT_VS_PPARG_KO_VISCERAL_ADIPOSE_TISSUE_TCONV_DN | 184 | 69 | 17377 | 2626 |
KCTD7,TOMM20,UROD,OLA1,SNN,UBE2I,MAPK14,PARK7,PABPC4,ANKRD28,CRKL,SNUPN,NOL11,MTMR4,THAP4,DNAAF2,RAB4A,SLC26A2,MCMBP,MOSPD1,FAM172A,CUL3,PSMG1,USP22,BICD2,CCNF,FANCE,DHX57,CLNS1A,SUPT16H,DAP3,FBXO28,U2SURP,RRS1,ZMAT3,RMND5A,PRPF38B,CDC40,FAM53C,CERK,HMG20A,WRB,BZW2,PDXDC1,ATG4A,SLC25A36,EBP,LRRC8D,DAD1,FEM1B,FBL,IMPA2,PDLIM2,AMPD2,PHF10,TIMM8B,ZFP64,GORASP2,UBE4B,RBM38,TMEM168,PARG,RBMX,TFDP1,LRPPRC,USP20,MEGF9,WIPI2,C7orf26 |
| 6.633e-14 | -30.34 | GSE15750_DAY6_VS_DAY10_EFF_CD8_TCELL_UP | MSigDB lists | GSE15750_DAY6_VS_DAY10_EFF_CD8_TCELL_UP | 184 | 69 | 17377 | 2626 |
SKA3,TXN,HNRNPAB,TPX2,NUF2,KIF2C,TCF19,MAP1LC3B,STMN1,OIP5,PSMD1,IMPAD1,KIF22,MYBL1,SENP1,PTPRK,PLK1,PBK,IDH3A,RAD51AP1,RRM2,CKAP2L,NUSAP1,CDC6,AURKB,BRCA1,SMC2,MCM2,SHCBP1,ASF1B,RAD54B,KIF18B,CEP55,KPNA2,POLQ,MCM10,MRPL9,DEPDC1,C1orf112,DBF4,CDCA8,RRM1,KIF23,RACGAP1,SUMF1,NCAPG,SPAG5,FBXO5,ARPC5,MCM5,PRC1,GTSE1,CENPM,KNTC1,C12orf75,GINS1,TK1,ASPM,MYBL2,KIF11,FAS,BIRC5,NEIL3,SNAP29,FAM83D,YWHAH,CCNB2,UBE2C,ESPL1 |
| 6.801e-14 | -30.32 | MORF_EIF3S6 | MSigDB lists | MORF_EIF3S6 | 119 | 52 | 17377 | 2626 |
COX5B,MRPL9,RPLP2,EIF3D,SUMO2,NACA,TKT,STARD7,LETMD1,COX4I1,DAZAP2,AP3S1,PARK7,NDUFS4,RAD23A,RAB8A,NDUFV1,HADHB,H2AFY,TCEA1,CYC1,FBL,EEF1D,PCBP2,CCT2,IFRD1,HMGN1,JTB,VDAC2,RPL6,SSR2,RPS24,H2AFV,DDX39A,EIF4H,EIF3G,SF3A2,SNRPA,EIF3H,CBX3,EIF3K,NAP1L1,DDOST,RPS27A,RBMX,COX7A2L,UQCRH,YWHAZ,MDH1,SRSF3,BTF3,FAU |
| 6.844e-14 | -30.31 | organelle inner membrane | cellular component | GO:0019866 | 506 | 139 | 18223 | 2701 |
COX15,NDUFB6,MRPS15,UQCR10,ABCB10,ATP5PF,MRPL19,PARK7,SLC25A37,GOT2,TIMM23,HADHB,TRA2B,NDUFB9,MRPL32,MRPL57,TIMM50,MRPL12,MRPL43,SLC25A22,NUTF2,FOXRED1,SLC25A5,MPC1,STOML2,TIMM13,TIMM29,NRM,MRPL27,MPV17,COX5A,UQCRH,DHFR2,SMAD1,MRPL13,SLC25A33,NDUFV2,COX5B,MRPL9,NEMP2,MRPS2,PHB2,NDUFA4,COX4I1,CYCS,PSEN1,NDUFS7,NDUFS4,NDUFAF6,BDH1,SLC25A51,MRPL48,CYC1,MRPL40,ALDH18A1,MRPL21,TIMM8B,ATP5IF1,SIGMAR1,COQ8A,NOA1,PGS1,MRPL16,TOMM40,MATR3,SDHB,COX7A2L,ATP5F1A,MRPL3,NDUFA5,IMMT,NDUFAF2,MRPL39,TOR1AIP1,BCL2L1,SLC25A44,LYN,SDHA,MRPL50,ANKLE1,MRPS27,MRPL34,MICU2,PARL,APOOL,PPIF,COQ10B,CPOX,DMAC2,NDUFA7,NDUFB1,MRPS14,TAZ,TMEM201,CHCHD3,MRPL2,DAP3,MRPL55,CHCHD1,TIMM17A,NDUFA11,SLC25A39,CDS2,NDUFS1,MRPL42,MRPS26,LETMD1,TIMM21,SLC25A12,ATP5F1B,SLC25A43,SLC25A36,NDUFV1,NDUFA2,COQ4,NDUFB4,CRAT,MRPL54,NDUFS8,MRPL11,STAT3,NDUFA3,SLC25A1,COA3,TIMMDC1,TMEM126B,MRS2,MRPS10,ATP5MF,GUF1,CHCHD6,CBX3,LEMD2,ATP5MC3,COX8A,LRPPRC,SLC25A19,NDUFS5,HIGD2A |
| 7.634e-14 | -30.20 | regulation of metabolic process | biological process | GO:0019222 | 6845 | 1212 | 17256 | 2622 |
ZBTB10,TSC2,HEXB,CCNL2,RBM4,ZNF275,FBXO22,EEF2K,RPL23A,CDKN2C,USF1,THAP4,RAD23B,DNM2,CRY2,ECD,ZNRD1,TIPARP,BAK1,ERCC1,ZNF559,GABPA,EHMT1,HNRNPF,WDHD1,MIER2,ARF4,BOLA3,AHNAK,MID1IP1,SMAD2,RPS27A,OGT,MPV17,RNASEL,SMAD1,ZNF75A,OAZ1,PDCD4,SLC25A33,ZNF720,HIVEP3,CLSPN,GGA1,DHX9,EIF2AK4,PSMD9,PARN,CDC73,TFAP4,CD59,SMC3,MEGF8,FBXO7,MYDGF,CPSF4,MVP,NUP85,PABPC1,PHKG2,NSUN4,PPP6R1,IFRD1,AGGF1,RBM42,FOXK1,MAPKAPK3,MTA2,GTPBP4,ITM2A,USP10,BCLAF1,ELK1,EIF4H,FNTA,KPNA1,PDLIM1,ETS2,ZNF830,NUP58,ALS2,RHOG,KARS,GGNBP2,NQO1,PTTG1,ANK3,TPX2,INO80E,DAZAP2,RCOR3,AHCTF1,ZNF420,MTA1,TBC1D14,GMEB1,NSFL1C,ZNF226,GPD1L,ZC3H3,RPRD1B,CGGBP1,PDCL3,CPNE1,ULK3,POLR2L,EID1,KAT7,RPL38,CIRBP,E2F3,POLR2D,HTATIP2,PFKFB3,MEF2D,RAB1A,PPP2CA,VPS26B,LSM6,CORO1C,PPP5C,USP13,COMMD10,ZNF445,SRSF6,ZFP91,HABP4,FLOT1,ABHD14B,WDR5,PMVK,NEXMIF,TUT4,PPP1R3B,GOLM1,RPA2,ZBTB45,PSMD2,PDCD10,ITGB8,ZNF260,LTN1,ZNF710,GTF2H2,MED22,PICALM,SH3BP5,GPS2,PARG,ACOX1,CD81,PARP10,YWHAH,THAP5,AAMDC,FAM129A,TRIM11,RBM8A,ENSA,NENF,SND1,TRIM65,FANCI,PAPOLA,ZER1,PRNP,CREM,TET3,RAB8A,NUP210,GLIS2,IL6ST,NOC2L,EIF5,MTPN,RYBP,PLK1,CELSR2,RBX1,RAD51AP1,ZBED5,CDC6,UBE2V1,PBRM1,EAF2,ODC1,USP21,CHD3,ZNF367,E2F4,ADAM9,KPNA2,DVL1,CLN3,BEND6,FAM208A,POT1,ZNF564,FUBP1,ZCCHC9,PHB2,DNAJB2,CENPF,NKD2,LAMTOR3,CHCHD2,CDK13,DNAJB1,CNOT11,ARID1B,SUB1,MLX,MBD2,SSBP3,ZNF746,ARL6IP1,CTR9,RBM3,ICE2,GLE1,LRSAM1,ACSL3,LDB1,MAP4K3,ZNF761,RBM38,IRF5,RMC1,RXRB,RPL36,MBIP,ORMDL2,LAMTOR4,NLRC5,RUVBL2,BTBD10,BCCIP,USP7,TRAF7,RPLP2,ARID2,ZNF416,RRAGC,ATP6V1B2,LYN,PCBP1,BCAP31,ZNF121,VAV1,NRF1,PSMA6,ZNF473,KMT5C,ZNF302,PIN1,PPME1,TARDBP,AHCYL1,STRAP,SPIDR,CTDSP2,ZNF583,PRPF19,SNX25,PPIF,KDM3B,BIRC3,POLR2G,ZNF780B,RAB7A,PPIE,NUP155,VDAC1,EIF3H,IDE,RBL1,UBXN2B,FASTK,STK38,UHRF2,CHMP4B,H3F3A,SMAD4,PARD3,BCL2L12,SLC30A9,UNK,MTERF1,AGO2,GTF3A,HMGN3,ARF1,CDK11B,PAGR1,SCYL2,FZD6,POLR1B,RNF5,RBM15B,YTHDC1,RHOA,RPRD1A,HMGN5,BTAF1,PRKDC,PCGF1,TRIM26,PDCD6,NEK1,ATP6V1D,L3MBTL3,BBX,E2F1,RBPJ,TAF12,NR2F2,PGAM1,HIPK3,IFI16,TXN,NUP188,MAX,H2AFZ,TSC22D3,CXXC1,UBE2I,MYEF2,PARK7,GLMP,PA2G4,NOL11,FIZ1,ZNF200,TRA2B,CISD2,TAF5L,SMARCE1,ZNF800,CDC5L,SRSF10,ZNF524,KLF10,LACTB,SUPT20H,USP22,CBFB,RFC2,EIF3A,ZMYM3,DOT1L,IWS1,MAP3K4,HHEX,MKNK1,BRD2,RPS14,BTF3,SLF1,CCDC59,NMD3,PTOV1,EWSR1,SCOC,POLR2K,GADD45G,VAV2,PRKAA1,GSPT2,CYCS,SUPT7L,ZNF79,ZNF518A,PSEN1,VPS25,YY1AP1,CNOT3,WDR48,LHX8,EXOSC7,PPP4R1,MSH2,DAPK1,PIK3IP1,TNRC18,FDFT1,SOCS5,EIF5A,ELL2,USF3,ZNF574,RPS24,EXOSC9,ARID1A,ADRB2,C9orf40,FXR1,PTTG1IP,MAP2K2,CCT8,TWISTNB,PHF6,XRCC5,DERL1,CAT,PFDN5,HSPBP1,GOLGA2,EPOP,RBMX,MED15,PIAS2,ARAP1,CEBPG,FAM83D,SAMD8,CABIN1,CDKN2A,ZNF511,NDC1,ATXN3,RAF1,CD320,EPM2A,SPINDOC,CCNA2,MTMR4,RALB,LPIN2,ADCY9,SOCS6,MRPS27,CDK12,SAP30,ANKLE2,BRD4,CDC123,DRAP1,ELP4,EDF1,PKMYT1,ERC1,SERP1,TRIM28,SUPT16H,EIF3K,ZNF282,CHMP4A,HINT1,DGCR8,CERS6,SAFB,ATF6,BEND3,EYA2,DEPDC1,MECP2,ARGLU1,SECISBP2,POFUT1,HMG20A,WWP2,CCNK,ELP5,FUT8,PTPN11,AXIN2,FEM1B,RPL19,CARF,CITED2,MSH6,KAT2A,LONRF3,RFXANK,KCNQ1,COMMD4,KLF6,FADD,SH3GLB1,CBX3,RPL32,LTBP4,ZHX1,OAZ2,PPP1R11,DDX5,WDR91,TAF6,PURA,DDB1,FAM83G,RORB,ZBED3,CCNC,ZNF76,KMT2E,PTP4A3,COMMD5,ZNF696,JAZF1,TCEA1,SLC35C2,DRAM2,CARM1,SRPK2,WDR41,DEAF1,LARS,NCK1,VHL,RIOX2,SREK1,KMT2C,ASF1B,RPL37,EIF4ENIF1,BRWD1,CAB39,BAZ1B,STK11,ZNF268,CHEK2,CLU,ATP6V0E1,CAPN1,UBE2D3,PPP1R2,PPP1R12A,GORASP1,NACA,UBXN1,RPL15,PM20D2,THRAP3,RGS2,TTF1,PRPF18,NUP205,LYAR,DTL,MED10,PYURF,MCPH1,ATP6V0D1,ATP5IF1,POLR2I,CREG1,ERLIN1,RPL6,GBA,EIF2A,SLTM,DAPK3,MASTL,KLHL15,NFIL3,SIAH2,YWHAZ,CTSA,EHD4,SNRNP70,TOB1,N4BP2L2,ADNP2,TCF12,PRKAB1,FEZ2,SMARCA4,ORC1,MXD1,USP5,HNRNPA2B1,SAP130,RRN3,UBXN2A,CD3EAP,NVL,KIF14,EXOSC1,UTP4,ZNF770,CHP1,POU2AF1,UBQLN4,PGGT1B,RNF25,SMU1,PCGF6,ATXN1,GLO1,EDEM2,TOLLIP,MBD3,RPS9,PDHX,HNRNPR,STAT6,ARNTL,MAPK1,BRD9,ABCA1,NAT14,DNAJC2,TRIP12,ZNF316,RAE1,SCYL1,NUP54,PAWR,MXD4,DCUN1D4,PIP4K2A,FASTKD3,FGFR3,KMT5A,NABP2,DUS2,H2AFY,ARHGEF2,ANP32A,ATG13,LDLRAD3,STAT3,TGFB1,ELOVL5,COA3,PPP1R9B,PHF20L1,DCAF6,HELB,PSPC1,MIER1,RFFL,RCOR1,PRMT2,CDK11A,TFEB,LEMD2,MTMR3,UPF1,ZC3H7B,KMT2B,CENPT,ZMIZ1,HRAS,SLF2,TERF1,FGFR1OP,MAP3K7CL,KDM4A,XIAP,AGPAT1,EDRF1,PPP1R16B,PABPC4,CDK5,CALM2,CIPC,PSMD1,NSRP1,SRSF4,FNIP2,NUP153,SENP1,MLST8,PLK3,ZNF672,AATF,MCL1,TOPORS,DCUN1D5,SLC50A1,PLEKHF2,STOML2,BRMS1,ZNF689,AXIN1,LIMK1,PRDX5,VIPAS39,MLYCD,ATP6V0C,SMG9,TRIM52,TFDP2,E2F2,LONP2,AAAS,SSRP1,PHF23,EZH1,LMNA,DDRGK1,MCTS1,PHF14,ZNF326,FOXN2,CYFIP1,ETV3,RB1CC1,ZMYND11,MYBL2,RPS10,SRSF5,CBFA2T2,MATR3,POLR2J,CSK,DUSP3,SETD3,CNOT6,RNF139,SGF29,EGLN1,ZNF207,PPP1R37,ZNF296,SARNP,TRERF1,IVNS1ABP,UBR2,WDTC1,MYH9,CREBL2,ZNF267,SAFB2,PRKACA,TCF19,APP,ANKIB1,SP100,ZKSCAN1,DDA1,NUP107,ANKRD13C,MAVS,RNF19A,CLN6,RBM15,ATF2,RNF169,ADCY7,ATP6V1G1,SHOC2,PSRC1,MAP4K4,RNPS1,WBP2,ATP6V0A1,CDCA2,DNAJA1,TAZ,DDX17,CHCHD3,TAF2,NT5C3B,HIPK2,RPLP1,TICAM1,FUS,ZBTB11,LRP8,ZNF786,RPS2,TRAK1,JMJD6,GMCL1,AKT1S1,ETS1,ZNF92,SUV39H2,PPP1R8,PRDM4,DCP1A,TPCN1,PDPK1,PPP3CA,TNFAIP3,ZNF512,JTB,ZP3,PDE3B,DDX39A,ZNF862,ZNF180,KEAP1,PITX1,MAPK6,PML,LRPPRC,HMGB2,PSAP,RGL1,USF2,IGBP1,FAF1,THOC1,AGRN,GPBP1L1,PPP1R15B,CSNK2A1,S1PR2,BIRC2,LIN9,ABL2,PCNA,ZNF639,ETV6,PIK3R2,MYBL1,CCAR1,PTPRK,CDC37,SP3,EXOSC6,BAZ2A,PBXIP1,MRPL12,GMFB,EZR,LRP5,BRCA1,PRKRA,RHEB,OPTN,TONSL,SOCS4,ACTB,ZNF45,LZTR1,CTCF,PPP3CB,RLF,ASXL2,CRLF3,LRRC14,RB1,NUS1,MED8,TIGAR,TIMELESS,AFF1,MDFIC,MAML1,PREB,TRAPPC9,UTP15,RTF1,EIF2AK1,KRAS,NFATC2IP,EIF4G2,ZNF174,PSMC4,SYNCRIP,TBPL1,PRMT7,RNF114,CYLD,FOXM1,DYNLL1,SUMO2,GGPS1,DUSP22,COMMD8,RPL11,RAD23A,CSDE1,PDK2,ATP6V0B,ZBTB21,MDM2,TNFAIP8,PDCD2,SAP30L,DVL2,RPL29,TIMP2,RPL35,PSMA8,BTG2,NFATC2,KDM1B,USP36,RPSA,SRSF1,DNAJC10,ATP1A1,CLK3,SCAP,ZNF700,MAFK,TIMM17A,PSMD3,ZNF436,PLGRKT,DNAJC17,NCOA1,ZNF146,CTDP1,MIF4GD,DAP,CDT1,ARID5A,NKRF,CSNK1A1,TFRC,WRNIP1,PTPN2,IRF4,SLC35B4,SS18L1,PTGES3,ZNF202,ZMYM5,BIRC5,TWSG1,TFE3,CDCA7L,GLG1,PKD2,ACADM,UBE2C,ZNF496,YTHDF3,CCNB1,EIF1B,COMMD6,RIC1,PARPBP,CDC25B,MAST2,PLCL2,DNMT1,SEH1L,AKT2,PBK,ELOA,MRNIP,DDX20,AURKB,TMED10,PSMD8,ITGB1,TRAF5,ARRB2,ZNF598,HDAC2,SVIP,DDX58,PPIB,HSPH1,GMFG,CHTF18,NOTCH2,PMF1,METTL3,JMY,NDUFS4,CFLAR,FKBP1A,MEX3C,KLF16,HDAC7,ATP6V0A2,PIKFYVE,LPCAT1,GNAI2,TMED2,EEF1D,TERF2,PHF10,ZNF84,NOA1,PIP4K2C,KCTD20,CYFIP2,KDM3A,PATL1,PSMB3,FAS,EPRS,ZNF777,SERTAD2,NSF,ZFP92,QARS,ACLY,PPP3R1,TCOF1,MAP3K5,PPP6R3,YY1,CDK2,RNF14,ZC3HAV1,DNMT3A,RWDD1,ZBTB37,RPS6KA1,CAST,SUZ12,SF3B1,EIF3D,RAC1,MAGED1,PAIP2,TERF2IP,CRKL,APLP2,ZNF75D,KDM2A,SHC1,UCHL5,CDKN1B,CCT2,RFC3,ERF,TAOK1,CUL3,H2AFV,PSMB9,CENPU,SOCS7,PRDM11,VEZF1,PPP2R5A,STAT1,H2AFX,TRIM32,ATMIN,CSNK1D,RHEBL1,POLQ,POU3F2,NCOR2,TCF3,BABAM1,MYNN,BLM,SPR,FOXO3,MAD2L2,GTF2F1,RBM17,RPL17,PTEN,UPF2,CREB1,MAP3K14,CNOT6L,NCOA2,TSHZ1,ZFP64,NEK7,WDR18,RPL8,PARP4,ILF3,TBRG4,RPL27A,MARK2,POLR2A,PRDX1,GNA12,HGS,PRDX3,TFDP1,KHSRP,BRWD3,CPEB2,VPS29,IER2,NOP2,HNRNPAB,UBN1,NF1,DNAJC24,ZNF107,SIRT2,TAF6L,UBQLN2,MAPK14,BECN1,SNAPC4,EDC3,ZNF804A,RAP1A,CYREN,EIF4A3,METTL14,PHTF1,PPP1R12C,SRI,ZBTB22,OGG1,ARID4A,TRIM14,ELOF1,COPS8,TRIM8,RRM2,SOX4,ABHD5,UBTF,GEMIN5,PAF1,PQBP1,ROCK1,RPS26,PSMC1,RPS15,TBC1D12,ZNF768,CIB1,MED13L,TIA1,MEF2A,EPHX2,SRRT,RHBDD1,APOPT1,NFATC3,ZNF449,BUD31,ZNF335,BCL2,YBX1,ACAD8,HP1BP3,ZNF189,VOPP1,CIC,OXR1,PSMA1,ISG15,CAND1,GNAS,TSC1,RBM25,NSMF,EXOC4,NUP62,ZFP90,RBBP4,HNRNPDL,SMARCD1,ZBTB24,MBD1,ASH1L,MPHOSPH8,IFI27L1,PLAGL2,NSD3,IRF3,CHD1,PAIP1,MEAF6,BABAM2,AKAP8,PARL,CHTOP,F2R,ABI1,HTRA2,RLIM,MOSPD1,FAM172A,ZNF500,PSMB7,NLN,BOLA1,ERBIN,PEF1,BTBD1,ZNF317,TAB2,TULP3,GADD45B,SCARB1,AKNA,SMURF1,PPP2R2D,CBX4,MIF,EYA1,DBF4,KLF13,FBXO5,PELO,TANK,BRD7,SAMD4B,TELO2,HMGN1,ADAM17,PRKAR1B,WDR81,MEN1,ZNF407,SYMPK,SNRPA,HSPA1B,MFN2,MAPK3,CNOT9,PLAA,ATAD2,OSBPL8,ZRANB2,SRSF3,ATP6V1C1 |
| 7.731e-14 | -30.19 | H2AFX (H2A histone family member X) | protein interactions | 3014 | 297 | 100 | 17029 | 2761 |
HNRNPAB,RPLP2,RAB11B,PRKCSH,CXXC1,CHD1L,CSNK2A1,SMARCA4,PAIP1,RPL23A,KRR1,CALM2,HNRNPA2B1,ZNF420,RPN2,TAF5L,PDIA6,ATF2,PCBP2,CFL1,PBK,TOPORS,SUMF2,BRCA1,MCM2,PEF1,TRIM28,RPS9,GINS4,SUPT16H,HNRNPR,RPS27A,TONSL,PPM1G,H2AFX,STK11,ACTB,CLU,BTF3,USP11,ARRB2,SSRP1,RPS15,RPS2,ZCCHC9,ANXA6,EYA1,NACA,C16orf87,DHX9,TKT,CTCF,BLM,FOXO3,POFUT1,LMNA,EIF2S2,HUWE1,MCM5,PHF14,TIMELESS,H2AFY,ANXA5,YBX1,RPL19,MCPH1,ANKHD1,PABPC1,TMX1,TERF2,LDHB,EIF3L,KAT2A,PRKDC,MIER1,ERO1A,RPS10,RPL8,ZNF574,PKM,MATR3,PSMB3,POLR2A,XRCC5,NAP1L1,UPF1,PDCD6,SYNCRIP,CCDC86,BIRC5,PRDX3,QARS,HNRNPH3,PML,NAXE,YWHAZ,HEXA,HNRNPDL,ZC3HAV1,ZBTB24 |
| 8.391e-14 | -30.11 | GSE7568_IL4_VS_IL4_AND_DEXAMETHASONE_TREATED_MACROPHAGE_UP | MSigDB lists | GSE7568_IL4_VS_IL4_AND_DEXAMETHASONE_TREATED_MACROPHAGE_UP | 161 | 63 | 17377 | 2626 |
POLA2,CHMP2A,RPS2,ADD1,MRPL42,GNPNAT1,ZCCHC8,NDUFAF2,POC1A,RACGAP1,IFT27,PCBP1,MIS12,CALM2,CDKN2C,PSMA6,EIF2S2,NDUFA2,CCDC50,SIVA1,RBM34,TIMELESS,AP2B1,YBX1,NDUFS8,GLTP,CLDND1,KNTC1,GNAI2,PABPC1,ELOF1,ACSL5,TDP1,TK1,WDR1,E2F3,CCDC34,WDHD1,PSMG1,NUP155,RANGAP1,CBFB,RFC2,API5,ECH1,GINS4,HAUS8,TAF2,DSN1,RAD18,NSF,PSMD8,TOMM6,QARS,NEIL3,CDCA5,DBI,COX5A,ANP32E,CHEK2,TAF6,ESPL1,FAM72A |
| 8.820e-14 | -30.06 | GSE9006_HEALTHY_VS_TYPE_1_DIABETES_PBMC_4MONTH_POST_DX_UP | MSigDB lists | GSE9006_HEALTHY_VS_TYPE_1_DIABETES_PBMC_4MONTH_POST_DX_UP | 193 | 71 | 17377 | 2626 |
USP7,SART1,COPA,TSC22D3,OLA1,GLUD1,DAZAP2,SAFB2,CPNE3,PABPC4,CREM,TERF2IP,NAPG,DPYSL2,DUT,SUCLG2,TAP2,STRAP,ILKAP,PCBP2,KLF10,AATF,LAP3,CIRBP,VDAC1,RAB5B,STK17B,BTBD1,SAFB,GADD45B,RNF38,ADAM9,REEP4,RTN3,ATMIN,NADSYN1,MAPRE1,FAM53C,TOR3A,PSMD2,RPN1,NDUFV1,PTEN,MBD2,ANXA5,FEM1B,OSTF1,AHCY,RBM3,COPS7B,PTGES3,MVP,PABPC1,HNRNPM,TMED2,PIGT,TNFAIP3,KIAA0930,MTMR12,EIF4H,SEC31A,TPD52L2,UAP1,ODF2,PRMT7,SIL1,YWHAZ,SPCS3,GPI,TOB1,ADNP2 |
| 8.951e-14 | -30.04 | GSE26030_TH1_VS_TH17_RESTIMULATED_DAY15_POST_POLARIZATION_DN | MSigDB lists | GSE26030_TH1_VS_TH17_RESTIMULATED_DAY15_POST_POLARIZATION_DN | 189 | 70 | 17377 | 2626 |
CHMP2A,UQCR10,RPS6KA1,COPE,RBM8A,PMS2,SLC35B2,GNB2,RPL11,RPL23A,CDK5,PCNA,EIF4A3,SIVA1,SRI,MRPL34,BRI3,CORO1A,TECR,MCMBP,NXT1,RPL38,PSMB7,NDUFA7,EDEM2,MBD3,NSA2,SMAD2,JAK1,CLK3,PSMD8,PRDX5,MRPL27,NDUFA11,ITGB1,DNAJC17,BTF3,SNRPG,FAU,PTOV1,C9orf78,SEC61G,SPR,PSMD9,CAPN2,DDX56,CBWD2,MED8,RPL17,PPIL2,RPL19,STAT3,PPP6R1,RNF5,S100A6,SIGMAR1,LDB1,POLR3GL,MAP7D1,DAPK3,SEC31A,PFDN5,RPL32,COX8A,CTSA,CABIN1,NDE1,EHD4,HIGD2A,ZNF511 |
| 1.000e-13 | -29.93 | proteasomal protein catabolic process | biological process | GO:0010498 | 334 | 104 | 17256 | 2622 |
ATXN3,UBR2,PTTG1,CUL1,NHLRC3,SIRT2,UBQLN2,CCNB1,UBE2I,BIRC2,RNF103,RAD23A,UBXN2A,PSMA6,PSMD1,MDM2,SIAH1,MTA1,KIF14,RAD23B,SOCS6,NSFL1C,ANAPC7,SPSB3,PCBP2,RLIM,PRPF19,PLK1,SEC61B,RBX1,PSMA8,CUL3,PSMB7,TOPORS,AURKB,CCNF,EDEM2,CDC23,PSMB9,BTBD1,ANKZF1,DNAJC10,CDC16,RPS27A,PSMD8,UBXN2B,PSMD3,AXIN1,ARNTL,RNF38,SEL1L,ATE1,KLHL42,FBXL3,SMURF1,ARRB2,PSMC1,USP13,UBE2D3,RMND5A,TMUB1,UBXN1,KCTD17,SDF2L1,UBE4A,CSNK1A1,PSMD9,RHBDD1,DNAJB9,NPLOC4,WWP2,PSMD2,RNF121,KLHL20,ZNRF2,GTSE1,LTN1,FBXL7,FBXL19,RNF5,ERLIN1,MAN1B1,RFFL,PSMA1,FBXO9,ANAPC2,UBE4B,SYVN1,ARMC8,PSMB3,PSMC4,DERL1,KEAP1,PLAA,CDC27,KLHL15,PML,DCAF11,ECPAS,UBE2C,RNF139,ANAPC4,DDB1,FAF1 |
| 1.036e-13 | -29.90 | REACTOME_MRNA_PROCESSING | MSigDB lists | REACTOME_MRNA_PROCESSING | 150 | 60 | 17377 | 2626 |
CDC40,NUP188,POLR2K,SF3B1,RAE1,SRSF6,RBM8A,NUP54,DHX9,SNRPD3,PCBP1,METTL3,NUP205,GTF2F1,SF3B2,PAPOLA,HNRNPA2B1,DNAJC8,ZNF473,NUP210,SRSF4,EFTUD2,NUP107,YBX1,NUP153,GTF2H2,NUP85,SEH1L,CCAR1,HNRNPM,PCBP2,CSTF1,SRSF11,SNRNP200,POLR2I,POLR2L,POLR2G,SNRPB,RNPS1,HNRNPF,POLR2D,SLBP,NUP155,SRSF5,TXNL4A,SF3A2,SNRPA,POLR2A,SRSF1,DDX23,SUGP1,POLR2J,HNRNPR,RBMX,NUP62,PRPF4,SRSF3,SNRPG,SNRNP70,AAAS |
| 1.095e-13 | -29.84 | GO_CELL_CYCLE_PHASE_TRANSITION | MSigDB lists | GO_CELL_CYCLE_PHASE_TRANSITION | 248 | 84 | 17377 | 2626 |
POLA2,FGFR1OP,CHMP2A,GPR132,FOXM1,DYNLL1,ENSA,TPX2,CUL1,ORC1,CCNB1,PRKACA,CALM2,CDKN2C,RAB8A,PCNA,AKAP8,PPP6C,DNM2,CDKN1B,CDC25B,CEP63,DCTN1,PLK3,PLK1,BRD4,CUL3,RRM2,CDC6,PKMYT1,CDC23,MCM2,OPTN,PRIM1,TAF2,RPS27A,E2F4,ITGB1,CHMP4B,CHEK2,PPP2R2D,CSNK1D,TUBB,CTDP1,MAPRE1,MCM10,PPP1R12A,DCTN2,CDT1,DBF4,HAUS4,CRLF3,HAUS2,FBXO5,RPA2,RB1,CCP110,CENPJ,MCM5,TIMELESS,FBXL7,ORC3,CAMK2G,PPP3CA,PRIM2,BORA,HAUS8,MASTL,RPA1,PCM1,POLE,CDC27,BIRC5,CDCA5,ODF2,E2F1,SSNA1,NDE1,CDK2,CHMP7,UBE2C,CCNB2,TERF1,CDKN2A |
| 1.133e-13 | -29.81 | MORF_UBE2N | MSigDB lists | MORF_UBE2N | 92 | 44 | 17377 | 2626 |
NDUFV2,MAPRE1,MRPL9,H2AFZ,HNRNPAB,CHERP,STARD7,CTCF,CYCS,PARK7,RAD23A,SF3B2,CALM2,NDUFV1,SMC3,PTPN11,TRA2B,TARDBP,PTGES3,PDIA6,HNRNPM,CCT2,IFRD1,SNRNP200,CDC123,TLK1,ILF3,TUFM,VDAC2,SLBP,DNAJC9,EIF4H,DDX39A,TRIM28,DHX15,SRSF1,CBX3,SDHB,KIF2A,HNRNPR,TATDN2,PPM1G,PRPS2,SRSF3 |
| 1.161e-13 | -29.78 | GNF2_CCNA2 | MSigDB lists | GNF2_CCNA2 | 66 | 36 | 17377 | 2626 |
HJURP,FOXM1,CENPF,TPX2,CDCA3,RRM1,CDCA8,RACGAP1,NCAPG,FANCI,PCNA,CCNA2,KIF14,PRC1,SMC4,PLK1,RFC3,ASPM,RAD51AP1,MKI67,RRM2,NUSAP1,SMC2,AURKB,MCM2,SHCBP1,KIF11,ASF1B,PRIM1,KIF18B,BIRC5,H2AFX,HMGB2,UBE2C,CCNB2,ESPL1 |
| 1.166e-13 | -29.78 | GNF2_SMC4L1 | MSigDB lists | GNF2_SMC4L1 | 82 | 41 | 17377 | 2626 |
HNRNPAB,FOXM1,CENPF,RRM1,CDCA8,RACGAP1,FANCI,FBXO5,DTL,PCNA,CCNA2,DUT,MCM5,PRC1,MSH2,NUP153,SMC4,GINS1,RFC3,NASP,ASPM,RAD51AP1,DNAJC9,SLBP,NUSAP1,SMC2,MCM2,SHCBP1,KIF11,GAR1,PRIM1,SUPT16H,CBX3,SRSF1,KIF18B,H2AFX,ANP32E,HMGB2,SNRPG,CCNB2,SSRP1 |
| 1.199e-13 | -29.75 | RNPS1 (RNA binding protein with serine rich domain 1) | protein interactions | 10921 | 194 | 74 | 17029 | 2761 |
ZNF207,USP7,TRIM41,COX15,SARNP,CHERP,SUZ12,SF3B1,RBM8A,XIAP,CUL1,CSNK2A1,PARK7,ZNF473,EIF4A3,PIN1,SRSF4,AP2B1,TRA2B,STRAP,CDK12,DVL2,PRPF19,SRPK2,UBQLN4,SNRNP200,RPL35,MKLN1,CUL3,RIOX2,SMU1,SREK1,DDX20,PRPF3,VDAC1,LUC7L,RPS9,SRSF1,DDX17,TAF2,TIMM13,LUC7L3,NKAPD1,PRPF4B,WSB2,RPS15,SRSF6,KIF23,THRAP3,CDK11B,PIP4K2A,SRRT,LMNA,CCNK,EFTUD2,UPF2,GEMIN4,HNRNPM,LUC7L2,SRSF11,GID8,FOXK1,ILF3,RPL6,SF3A2,CDK11A,SNRPA,ZFR,DDX23,CAND1,RPL36,UPF1,RBM25,SNRNP70 |
| 1.223e-13 | -29.73 | MORF_ESPL1 | MSigDB lists | MORF_ESPL1 | 57 | 33 | 17377 | 2626 |
POLA2,H2AFZ,HNRNPAB,CHERP,FOXM1,RRM1,CYCS,RAD23A,KIFC1,HNRNPA2B1,GOT2,CS,TARDBP,PTGES3,DNMT1,NUDC,PLK1,DNAJC9,GLO1,AURKB,VDAC1,MCM2,KIF11,TRIM28,SNRPA,MFAP1,TFDP1,PPM1G,PRPS2,KHSRP,BAZ1B,ESPL1,SSRP1 |
| 1.237e-13 | -29.72 | REACTOME_DNA_REPLICATION | MSigDB lists | REACTOME_DNA_REPLICATION | 182 | 68 | 17377 | 2626 |
POLA2,NUF2,KIF2C,ORC1,MIS12,PCNA,PSMD1,CCNA2,AHCTF1,PSMA6,NUP107,CDKN1B,SEH1L,PLK1,RFC3,PSMA8,TAOK1,PSMB7,E2F3,CDC6,AURKB,MCM2,PSMB9,RFC2,GINS4,PRIM1,KIF2A,PPP2CA,PPP2R5A,DSN1,RPS27A,PSMD8,PSMD3,E2F2,PSMC1,MCM10,MAPRE1,GORASP1,CDT1,DBF4,CDCA8,KIF23,PMF1,PSMD9,FBXO5,RPA2,PSMD2,RB1,SMC3,MCM5,CENPM,KNTC1,ORC3,NUP85,NUDC,GINS1,PRIM2,PSMA1,RANGAP1,PSMB3,RPA1,PSMC4,KIF18A,POLE,BIRC5,E2F1,CENPT,CDK2 |
| 1.239e-13 | -29.72 | peptide biosynthetic process | biological process | GO:0043043 | 399 | 118 | 17256 | 2622 |
KARS,CYLD,RPLP2,RWDD1,MRPS15,MRPL39,EIF3D,EFL1,EIF1B,RBM4,MRPL19,PAIP1,PABPC4,EEF2K,RPL23A,RPL11,MRPL50,FARSA,IARS,MRPS27,MRPL34,EIF5,MRPL32,MRPL57,RPL29,LARS,RPL35,HARS,MRPL43,RPL38,MRPL12,NDUFA7,POLG2,MRPS14,EIF3G,RPS9,EIF3H,RPSA,EIF3A,RPL37,EIF3K,GEMIN5,MRPL2,DAP3,MRPL55,RPS27A,RPS14,CHCHD1,MRPL27,EIF2D,PPA2,RPLP1,FTSJ1,IARS2,QRSL1,MRPL13,RPS26,ZNF598,PDF,GCLM,RPS15,MRPL9,RPS2,MRPL42,MRPS2,DHPS,AGO2,GSPT2,MRPS26,RPL15,SECISBP2,CHAC2,GFM2,MCTS1,EIF2S2,GATC,RPL17,EFTUD2,PELO,RRBP1,MRPL54,LTN1,RPL19,MRPL40,MRPL48,MRPL21,MRPL11,GTF2H2,PPA1,PABPC1,RPL22L1,EEF1D,CARS2,EIF5A,EIF3L,DHX29,NOA1,RPL6,RPL8,TUFM,RPS10,MRPS10,RPS24,MRPL16,EIF2A,HAGH,EIF4H,EIF4G2,RPL27A,GUF1,ABCF1,TARS,RPL36,EPRS,RPL32,QARS,CPEB2,MRPL3 |
| 1.240e-13 | -29.72 | BMI1 (BMI1 proto-oncogene, polycomb ring finger) | protein interactions | 648 | 389 | 121 | 17029 | 2761 |
USP7,IMMT,MPHOSPH8,CHERP,TMEM41B,DYNLL1,YTHDF3,SMARCA4,UBE2I,SAFB2,MAPK14,MYEF2,KTN1,PAIP1,PABPC4,KRR1,PHC2,STRBP,EIF4A3,AKAP8,TARDBP,AQR,CHTOP,CLN6,STRAP,TIMM50,CSTF1,SRPK2,RYBP,DPM1,EHMT1,PPIE,PCGF6,CRNKL1,CIRBP,CUL3,RNPS1,SMU1,CDC6,DIDO1,PRKRA,TRIM28,SUPT16H,GEMIN5,SUGP1,DGCR8,CHD3,LUC7L3,RPLP1,ATXN2L,H2AFX,UHRF2,BAZ1B,KPNA2,FUS,USP11,FAM208A,PDCD11,CBX4,HDAC2,UBE2D3,PPIB,EWSR1,ZCCHC8,TWNK,AGO2,RRM1,TIA1,CTCF,NDUFA4,NKRF,THRAP3,ATP5F1B,WDR5,SRRT,LMNA,ERH,RPN1,PTEN,BANF1,EFTUD2,BUD31,RTCB,ZNF326,H2AFY,YBX1,SS18L1,GEMIN4,FBL,TERF2,HP1BP3,YTHDC1,STAU1,CSRP1,PRRC2A,MAPKAPK3,PSPC1,PRKDC,SUGP2,TUFM,ILF3,BCLAF1,PLEC,FXR1,PCGF1,SLTM,ZFR,PHF6,XRCC5,CBX3,UTP20,UPF1,LRPPRC,DUSP11,RUVBL2,YY1,CFAP20,PDLIM5,PURA,ZC3HAV1,RNF114 |
| 1.240e-13 | -29.72 | GSE21063_CTRL_VS_ANTI_IGM_STIM_BCELL_NFATC1_KO_8H_DN | MSigDB lists | GSE21063_CTRL_VS_ANTI_IGM_STIM_BCELL_NFATC1_KO_8H_DN | 178 | 67 | 17377 | 2626 |
TXN,TRERF1,MCCC1,STMN1,FANCI,CDKN2C,DECR1,CCNA2,IARS,DUT,SRI,AP2B1,RNASEH2A,NAA35,POC5,RFC3,PSRC1,CCDC138,KIF15,ELP4,CDCA2,SMC2,NUTF2,ANLN,ASF1B,PRIM1,CHCHD3,CCDC14,MPV17,ANP32E,CHEK2,CHID1,MCM10,PKP4,PIGN,HJURP,FLOT1,BLM,NCAPG,MYL6B,SPAG5,SAC3D1,MCTS1,MCM5,ATIC,FUT8,PHF14,KNTC1,ORC3,TTLL12,RPL22L1,MAPKAPK3,ASPM,ZNF512,C9orf40,STYXL1,TARS,EPRS,MTHFD2,BIRC5,TFDP1,AEN,MAP3K5,CCNB2,RPS6KC1,ALS2,VPS29 |
| 1.293e-13 | -29.68 | DLST (dihydrolipoamide S-succinyltransferase) | protein interactions | 1743 | 266 | 92 | 17029 | 2761 |
CHMP2A,IMMT,PDCD6IP,THOC1,MRPL39,PHRF1,MDH2,RBM8A,TAP1,DHX8,SND1,OAT,RBM4,CALM2,DLG5,RAP1A,EIF4A3,MTA1,RPN2,TECR,CHTOP,PDIA6,PRPF19,CCT2,RAB7A,MRPL12,VDAC2,CRNKL1,RNPS1,NLN,OGDH,RAB1A,SLC25A5,MRPS14,LUC7L,H2AFV,GAR1,TRIM28,STOML2,CHCHD3,MRPL2,HPS5,SAFB,CORO1C,MYO18A,CHMP4B,PSMC1,USP13,FLOT1,TOP2B,THRAP3,ATP5F1B,LMNA,HLA-A,KIF5B,RPN1,GART,RRBP1,H2AFY,BRD7,TAGLN2,MRPL40,FBL,PABPC1,EEF1D,LDHB,HP1BP3,EIF5A,YTHDC1,NTPCR,MLEC,RHOA,ZNF512,MTA2,SF3B6,RANGAP1,CAPZA2,PLEC,PICALM,PSMC4,DDX23,MAGED2,EPRS,NAP1L1,CCDC86,PRDX3,ZHX1,HNRNPH3,SIAH2,ACAT1,YWHAZ,PGAM1 |
| 1.400e-13 | -29.60 | mitochondrial inner membrane | cellular component | GO:0005743 | 447 | 126 | 18223 | 2701 |
NDUFA5,COX15,IMMT,NDUFB6,MRPS15,NDUFAF2,MRPL39,UQCR10,ABCB10,BCL2L1,SLC25A44,ATP5PF,LYN,SDHA,MRPL19,PARK7,SLC25A37,MRPL50,GOT2,TIMM23,MRPL34,HADHB,MRPS27,PARL,MICU2,NDUFB9,APOOL,MRPL32,MRPL57,TIMM50,PPIF,COQ10B,CPOX,DMAC2,MRPL12,MRPL43,SLC25A22,NDUFA7,NDUFB1,FOXRED1,SLC25A5,TAZ,MRPS14,MPC1,STOML2,CHCHD3,MRPL2,DAP3,TIMM13,MRPL55,CHCHD1,TIMM29,TIMM17A,NDUFA11,MRPL27,MPV17,COX5A,UQCRH,DHFR2,MRPL13,SLC25A39,SLC25A33,COX5B,NDUFV2,CDS2,NDUFS1,MRPL9,MRPL42,PHB2,MRPS2,MRPS26,LETMD1,TIMM21,SLC25A12,NDUFA4,COX4I1,CYCS,ATP5F1B,SLC25A43,PSEN1,NDUFS7,NDUFS4,SLC25A36,NDUFAF6,NDUFV1,COQ4,NDUFA2,NDUFB4,CRAT,BDH1,SLC25A51,MRPL54,NDUFS8,MRPL48,CYC1,MRPL40,MRPL11,ALDH18A1,MRPL21,NDUFA3,STAT3,SLC25A1,ATP5IF1,COA3,TIMM8B,COQ8A,TIMMDC1,NOA1,PGS1,TMEM126B,MRS2,MRPS10,MRPL16,ATP5MF,TOMM40,GUF1,CHCHD6,SDHB,ATP5MC3,COX7A2L,COX8A,SLC25A19,ATP5F1A,NDUFS5,MRPL3,HIGD2A |
| 1.555e-13 | -29.49 | microtubule cytoskeleton | cellular component | GO:0015630 | 1151 | 261 | 18223 | 2701 |
FGFR1OP,PDCD6IP,TAP1,CNTROB,CCNB1,KIFC1,CDK5,CALM2,ANKRD26,NEK6,DNM2,MAST2,CDC25B,SPATC1L,KCNAB2,PLK3,NSUN2,KIF15,TOPORS,AURKB,DIDO1,CCNF,MCM2,SLC25A5,EIF3A,KRIT1,MID1IP1,RAD18,KIF18B,WDR11,MAP4,KLHL42,SLF1,TRAF5,AAAS,ANXA11,HSPH1,MAPRE1,DHX9,RAB23,KIF23,HAUS4,PSEN1,HAUS2,SPAG5,TMEM250,CEP104,SMC3,FBXL7,GNAI2,NUP85,SEPT8,MAP7D1,MAP2K2,CCT8,FNTA,GOLGA2,FAM83D,NDE1,CFAP20,CDK2,ALS2,ZNF207,NDC1,POC1A,OLA1,TPX2,MYH9,NIT2,BCL2L1,PRKACA,STMN1,APP,CLUAP1,MTA1,SEPT11,RNF19A,CEP63,RPRD1B,DCTN1,CCT2,PSRC1,MAPRE2,CUL3,NUSAP1,DNAJA1,SHCBP1,SERP1,EML4,CENPU,PPP2CA,KIF2A,CDC16,DSN1,PPP2R5A,CCDC14,H2AFX,GEN1,LRP8,CSNK1D,TUBB,DYNC1LI2,PKP4,MZT1,MECP2,FLOT1,WDR5,SPDL1,IFT27,RAB11A,MAD2L2,NEIL2,JAKMIP1,CLIC4,CENPJ,PRC1,AXIN2,GTSE1,IFT46,SPTAN1,NUDC,STAU1,KAT2A,TCTEX1D2,TACC1,NEK7,JTB,PARP4,MACF1,KIF11,SPPL2B,CBX3,KIF18A,KEAP1,TTLL4,LRPPRC,CCDC69,SSNA1,WDR62,ESPL1,NPHP4,SKA3,KMT2E,WDR13,SIRT2,KIF2C,MAPK14,MAP1LC3B,DLG5,ZNF804A,DST,RAB8A,PCNA,CDC42,DPYSL2,XRCC2,KIF22,RP2,TACC3,RPP25,PLK1,SEPT9,PBXIP1,FOPNL,CKAP2L,EZR,CDC6,BRCA1,HSPB11,SEPT1,CHD3,VPS4A,ROCK1,DVL1,SASS6,C2CD5,CEP170B,TMUB1,PPP1R12A,CENPF,CIB1,KLC1,RACGAP1,RAPGEF6,DTL,RB1,CCP110,KIF13B,KIFAP3,KNTC1,MCPH1,ATP6V0D1,CAMSAP1,PSMA1,SEPT7,MASTL,HAUS8,PCM1,CDC27,ODF2,NLRC5,SLC16A1,NUP62,RUVBL2,ECPAS,CCNB2,MZT2B,BCCIP,CYLD,FAM92A,DYNLL1,PMS2,RAD23A,STRBP,ABRAXAS2,KIF14,DNAL4,POC5,CHP1,PRPF19,TUBGCP5,BICD2,TMEM201,CEP55,AKNA,MAPK1,REEP4,SMAD4,RAD51D,KIF3B,CTDP1,KLHL21,RAE1,CDK2AP2,DCTN2,SCYL1,CDCA8,CSNK1A1,TUBGCP2,SAC3D1,FBXO5,KIF5B,STARD9,MZT2A,SLC1A4,ARHGEF2,MYO5A,MICAL3,ASPM,RANGAP1,HSPA1B,MFN2,NEK1,ATP6V1D,FAM110A,BIRC5,SNAP29,E2F1,USP20,PKD2,TERF1 |
| 1.559e-13 | -29.49 | V$NRF2_01 | MSigDB lists | V$NRF2_01 | 258 | 86 | 17377 | 2626 |
COX15,CHERP,NF1,PRKCSH,EIF3D,MON1B,DHX8,BCL2L1,POMP,DAZAP2,SYNRG,CUTC,FBXO22,EDC3,C14orf119,SEC11A,USF1,SHC1,MTMR4,PPME1,SRSF4,UBA5,AP1M1,NOC2L,DNMT1,SENP1,MTPN,FGFR1OP2,KCNAB2,PRPF19,RPL29,ERCC1,NRAS,CDC123,COQ10B,LYRM1,RNPS1,ARL5B,RPL37,TBC1D17,DDOST,ZNF689,E2F4,PRDX5,UQCRH,ZBTB11,CHPF2,AAAS,CWC25,HSPH1,PHB2,PHF23,SRSF6,UFC1,UBXN1,EPN1,AKT1S1,HMG20A,WWP2,FBXO3,MED8,ARPC5,VMP1,MEGF8,SEC24C,BCL2,GNAI2,EIF5A,TIMM8B,MLEC,ACP2,BTAF1,RPL6,TUFM,RPS10,LRRC1,SYVN1,TOMM40,DDX39A,PHF6,ATP6V1D,PALB2,DDX5,RGL1,PLOD3,MRPL3 |
| 1.632e-13 | -29.44 | GSE1460_INTRATHYMIC_T_PROGENITOR_VS_NAIVE_CD4_TCELL_CORD_BLOOD_UP | MSigDB lists | GSE1460_INTRATHYMIC_T_PROGENITOR_VS_NAIVE_CD4_TCELL_CORD_BLOOD_UP | 191 | 70 | 17377 | 2626 |
TCF12,IMMT,TXN,HNRNPAB,UCK2,ENSA,CSNK2A1,CUL1,KIF2C,ORC1,SND1,STMN1,PA2G4,PCNA,CCNA2,PSMA6,GOT2,TCEA1,TP53BP2,TDP1,TIMP2,GABPA,IDH3A,LYRM1,SMC2,FKBP3,RHEB,CHCHD3,PON2,RAD51C,CDCA4,IDE,SMAD2,HNRNPR,BAZ1B,TUBB,HIVEP3,C1orf112,RRM1,MYL6B,RMI1,COPB2,TFRC,FBXO5,PTPN2,PPP4R1,MSH2,PRC1,TIMELESS,UPF2,MRPL11,IMPA2,GINS1,RHOA,SIGMAR1,ERLIN1,NSDHL,MYBL2,GORASP2,UBE4B,CBX3,ETS2,SNAP29,MFAP1,PGRMC1,HMGB2,PSAP,ATP6V1C1,IFI16,ADNP2 |
| 1.633e-13 | -29.44 | GO_SISTER_CHROMATID_SEGREGATION | MSigDB lists | GO_SISTER_CHROMATID_SEGREGATION | 163 | 63 | 17377 | 2626 |
ZNF207,CHMP2A,MAPRE1,PDCD6IP,PHB2,CENPF,CDCA8,KIF23,RACGAP1,NUF2,TOP2B,KIF2C,PMF1,CCNB1,BECN1,NCAPG,RAB11A,MIS12,SPAG5,KIFC1,RB1,SMC3,AHCTF1,KIF14,AKAP8,PRC1,NUP107,PDS5B,NAA50,KIF22,KNTC1,CENPM,MCMBP,NUP85,SEH1L,SMC4,NUDC,PLK1,PSRC1,TAOK1,CUL3,NUSAP1,RANGAP1,AURKB,SMC2,CDC23,CHMP2B,KIF2A,RAD51C,KIF18A,CHMP4A,KIF18B,DSN1,BIRC5,CDCA5,CEP55,CHMP4B,VPS4A,CENPT,RRS1,NDE1,CHMP7,ESPL1 |
| 1.648e-13 | -29.43 | nuclear chromosome | cellular component | GO:0000228 | 586 | 154 | 18223 | 2701 |
POLA2,MAX,H2AFZ,THOC1,CSNK2A1,SIRT2,CCNB1,UBE2I,MIS12,USF1,PCNA,MCMBP,SMARCE1,CDC5L,PLK1,ERCC1,GABPA,RAD51AP1,WDHD1,WDR82,SMC2,PBRM1,AURKB,BRCA1,MCM2,GINS4,ASF1B,PRIM1,CHAF1A,BRMS1,SMAD2,TONSL,CHD3,E2F4,BAZ1B,ACTB,RRS1,SINHCAF,POT1,HDAC2,DHX9,MEF2A,ASXL2,CDC73,ARID1B,YY1AP1,RB1,SMC3,MCM5,MBD2,XPA,MSH2,BUD31,TIMELESS,KIFAP3,TERF2,PHF10,ETV3,PRIM2,MTA2,LDB1,EXOSC9,ARID1A,APPL1,XRCC5,NSMF,SETD3,RBMX,CDCA5,APPL2,RUVBL2,YY1,RBBP4,SMARCD1,TCF12,DNMT3A,MPHOSPH8,SUZ12,SMARCA4,NUF2,INO80E,ORC1,MXD1,TERF2IP,SAP130,SP100,KMT5C,UCHL5,NABP1,TARDBP,TOP1MT,SPIDR,PRPF19,BRD4,WBP2,NFATC2,DCLRE1C,MEF2D,H2AFV,MBD3,GAR1,TRIM28,DSN1,STAT6,STAT1,UHRF2,H2AFX,XRCC3,ANP32E,BEND3,NCOA1,H3F3A,SMAD4,RAD51D,NCOR2,NIFK,MCM10,TCF3,PAWR,BLM,WRNIP1,RPA2,IRF4,ADD3,NABP2,H2AFY,SS18L1,ORC3,CREB1,CITED2,STAT3,MSH6,GINS1,TELO2,NASP,KAT2A,PRKDC,HELB,POLR3GL,MEN1,RPA1,CBX3,UPF1,POLE,BIRC5,PML,E2F1,LRPPRC,HMGB2,CENPT,TERF1,PURA,DDB1,IPO4 |
| 1.653e-13 | -29.43 | GO_MITOTIC_SISTER_CHROMATID_SEGREGATION | MSigDB lists | GO_MITOTIC_SISTER_CHROMATID_SEGREGATION | 86 | 42 | 17377 | 2626 |
ZNF207,CHMP2A,PDCD6IP,CDCA8,KIF23,RACGAP1,KIF2C,CCNB1,NCAPG,BECN1,RAB11A,MIS12,SPAG5,KIFC1,RB1,SMC3,KIF14,AKAP8,PRC1,NAA50,PDS5B,KIF22,SEH1L,SMC4,PLK1,PSRC1,CUL3,NUSAP1,AURKB,SMC2,CDC23,CHMP2B,KIF18A,CHMP4A,KIF18B,CEP55,CDCA5,CHMP4B,VPS4A,RRS1,CHMP7,ESPL1 |
| 1.661e-13 | -29.43 | WANG_RESPONSE_TO_GSK3_INHIBITOR_SB216763_DN | MSigDB lists | WANG_RESPONSE_TO_GSK3_INHIBITOR_SB216763_DN | 329 | 102 | 17377 | 2626 |
CYTIP,H2AFZ,HNRNPAB,URB2,PTTG1,SLC2A1,EBNA1BP2,NUF2,PLXNA1,STMN1,TCF19,KIAA1147,PAIP2,ANKRD28,CCNA2,XRCC2,GMEB1,KIF22,TIPARP,SEH1L,RFC3,GABPA,RAD51AP1,PBK,EZR,RRM2,CDC6,BRCA1,DNAJA1,SMC2,PKMYT1,DCUN1D5,MCM2,SHCBP1,RFC2,GINS4,ASF1B,CHAF1A,CDCA4,NIP7,ZNF367,WDR4,PTPN7,H2AFX,SNRPG,TFDP2,E2F2,LRP8,PFKP,PDCD4,B4GALT2,MIF,HSPH1,MCM10,GMFG,CLSPN,CCM2,KIF23,SDF2L1,FAM136A,BLM,ITGB5,NCAPG,CCDC28A,TFRC,WDR48,PNO1,EBP,DTL,RFWD3,LYAR,GART,SLC1A4,SLC38A5,MCM5,AHSA1,MSH2,GEMIN4,CENPM,CITED2,LPCAT1,MSH6,PREB,GINS1,TK1,NASP,TNFAIP3,RB1CC1,ACSL3,MYBL2,UTP15,LY6E,HSPA1B,MASTL,RAB18,SLCO4A1,ATAD2,SLC16A1,SLC25A19,CDK2,CABLES1,BYSL |
| 1.691e-13 | -29.41 | BASAKI_YBX1_TARGETS_UP | MSigDB lists | BASAKI_YBX1_TARGETS_UP | 267 | 88 | 17377 | 2626 |
POLA2,PTTG1,TPX2,NUF2,KIF2C,CCNB1,FANCI,CREM,OIP5,CCNA2,SIVA1,PDCD2,KIF22,RNF26,MYBL1,PLK1,RFC3,TIMP2,POLR2L,PBK,MKI67,HTATIP2,WDHD1,DNAJC9,CDC6,AURKB,PRPF3,SMC2,DCUN1D5,MCM2,ANLN,SHCBP1,RFC2,H2AFV,ASF1B,RHEB,CHAF1A,DPYSL3,HINT1,ZNF367,WDR4,CEP55,H2AFX,CBWD1,KPNA2,RRS1,MCM10,DEPDC1,HJURP,CCM2,CDK2AP2,CDCA8,CDCA3,DHX9,KIF23,KLC1,SAC3D1,DTL,PSMD2,GART,MED8,MCM5,AHSA1,PRC1,GTSE1,SLC38A10,CENPM,GINS1,TK1,ASPM,PRKDC,WDR1,RANGAP1,ADRB2,BORA,DDX39A,COMMD4,GALNT2,BIRC5,FAM83D,HMGB2,EHD4,CDK2,UBE2C,CCNB2,YWHAH,ESPL1,TSEN15 |
| 1.694e-13 | -29.41 | MORF_PSMC1 | MSigDB lists | MORF_PSMC1 | 175 | 66 | 17377 | 2626 |
KARS,HNRNPAB,ENSA,CDIPT,RBM4,BCAP31,MBD4,SF3B2,UTP18,SIVA1,RAD23B,PPP6C,TECR,EIF5,CCT2,POLR2G,DPM1,CDC123,GMFB,TMEM147,NDUFB1,STX16,STOML2,PAF1,TMED10,PSMD8,COX5A,KPNA2,SNRPG,PITRM1,PSMC1,AP2S1,COIL,MYL12B,ATP6V0E1,FUBP1,SEPHS2,NDUFS1,MRPL9,RAE1,DCTN2,CTCF,COX4I1,UBE4A,PSMD9,ERH,NDUFA2,ATIC,ARF5,BANF1,BUD31,CYC1,TMED2,EEF1D,HMGN1,RBM42,JTB,SSR2,COMMD4,CBX3,PSMC4,PDCD6,SETD3,COX7A2L,SSNA1,YY1 |
| 1.791e-13 | -29.35 | ZNF746 (zinc finger protein 746) | protein interactions | 155061 | 288 | 97 | 17029 | 2761 |
COPA,NOP2,RPLP2,FAM207A,EIF3D,MCCC1,MOGS,GLUD1,CPNE3,PABPC4,FARSA,ATP2A2,IARS,NUP107,MRPS27,HADHB,NOC2L,RPN2,TARDBP,ABI1,FTSJ3,TIMM50,CDC5L,SRP72,SNRNP200,RPL35,FAM118B,NSUN2,HNRNPF,DNAJC9,PRKRA,SLC25A5,TRIM28,RPS9,DHX15,RPSA,EIF3A,SRSF1,ZNF282,DAP3,ATP1A1,HNRNPR,TBL3,PSMD3,PSMC1,GALK1,RPS15,RPS2,MRPS2,PHB2,DHX9,SLC25A12,NCKAP1,ATP5F1B,TUBGCP2,COPB2,LYAR,PSMD2,RPN1,AHSA1,EFTUD2,ZNF746,MSH2,CYC1,FBL,MRPL11,MSH6,HNRNPM,SLC25A1,LDHB,CYFIP1,NTPCR,EIF3L,COQ8A,PRKDC,RPL6,LDHA,RPL8,ILF3,TUFM,RPS24,PKM,RPL27A,CAND1,RPL36,XRCC5,MAGED2,SYNCRIP,OSBPL8,RBMX,ACLY,LRPPRC,ATP5F1A,SRSF3,PPP6R3,DDB1,BYSL |
| 1.844e-13 | -29.32 | mitochondrial membrane | cellular component | GO:0031966 | 668 | 170 | 18223 | 2701 |
COX15,NDUFB6,MTX3,MRPS15,UQCR10,ABCB10,BECN1,ATP5PF,MRPL19,PARK7,SLC25A37,GOT2,TIMM23,SLC44A1,HADHB,DNM2,NDUFB9,CISD2,TRIM14,MRPL32,MRPL57,TIMM50,BAK1,MRPL12,MRPL43,SLC25A22,MCL1,FOXRED1,SLC25A5,MPC1,STOML2,TIMM13,RPS27A,TIMM29,MRPL27,MPV17,COX5A,UQCRH,DHFR2,CLU,MRPL13,SLC25A33,NDUFV2,COX5B,MRPL9,MRPS2,PHB2,NDUFA4,COX4I1,CYCS,PSEN1,NDUFS7,NDUFS4,NDUFAF6,TIGAR,BDH1,SLC25A51,BCL2,MRPL48,CYC1,MRPL40,ALDH18A1,MRPL21,TIMM8B,ATP5IF1,COQ8A,NOA1,PGS1,ACSL3,MRPL16,MTX1,TOMM40,SFXN5,CYB5A,AKAP1,SDHB,COX7A2L,ATP5F1A,NIPSNAP2,TMEM14A,MRPL3,NDUFA5,IMMT,TOMM20,ATXN3,NDUFAF2,RAF1,MRPL39,STARD7,BCL2L1,SLC25A44,SNN,LYN,SDHA,MIEF1,MOAP1,MRPL50,MRPS27,MRPL34,PARL,MICU2,MAVS,APOOL,ATF2,TMEM14C,HTRA2,ACSL5,PPIF,COQ10B,CPOX,DMAC2,VDAC2,OGDH,NDUFA7,NDUFB1,VDAC1,MRPS14,TAZ,ANKZF1,CHCHD3,MRPL2,DAP3,MRPL55,CHCHD1,TIMM17A,TOMM6,NDUFA11,SLC25A39,CDS2,NDUFS1,MRPL42,MRPS26,LETMD1,TIMM21,SLC25A12,ATP5F1B,SLC25A43,FOXO3,SLC25A36,NDUFV1,NDUFA2,COQ4,NDUFB4,CRAT,MRPL54,NDUFS8,MRPL11,NDUFA3,STAT3,MTX2,RNF5,SLC25A1,COA3,TIMMDC1,TMEM126B,MRS2,MRPS10,ATP5MF,RHOT1,GUF1,RHOT2,CHCHD6,SH3GLB1,MFN2,ATP5MC3,COX8A,SLC25A19,NDUFS5,ACADM,HIGD2A |
| 1.849e-13 | -29.32 | MODULE_32 | MSigDB lists | MODULE_32 | 233 | 80 | 17377 | 2626 |
RAB14,KARS,RPLP2,SUCLG1,EIF3D,SNRPD3,PCBP1,RBM4,PABPC4,MBD4,RPL11,RAD23A,RPL23A,HNRNPA2B1,EIF4A3,RALB,TRA2B,RNASEH2A,EIF5,PCBP2,SRSF10,RPL29,RPL35,POLR2G,MRPL12,HNRNPF,CIRBP,RPL38,SLBP,EIF3G,ARF4,EIF3H,CHAF1A,RPL37,HNRNPR,RPLP1,RBMS1,SNRPG,CBX4,FUBP1,RPS15,EWSR1,RPS2,SRSF6,RPL15,ARFIP2,RAB11A,SUB1,RPN1,RPL17,ARF5,EFTUD2,YBX1,RBM3,RPL19,FBL,GNAI2,PABPC1,EEF1D,EIF5A,SRSF11,RHOA,RPL8,TUFM,RPL6,RPS10,PSMA1,RPS24,RIT1,RPL27A,EIF4H,EIF4G2,SNRPA,XRCC5,RPA1,GNAS,GNA12,RPL32,RBMX,MRPL3 |
| 1.964e-13 | -29.26 | MORF_CDK2 | MSigDB lists | MORF_CDK2 | 70 | 37 | 17377 | 2626 |
NUP188,H2AFZ,HNRNPAB,SUMO2,STARD7,SLC4A2,XPO7,EBP,HNRNPA2B1,RPA2,PSMD2,DNAJC8,ARL6IP1,CS,TCEA1,SNRNP200,AATF,PRKDC,PSMB7,PKMYT1,ESYT1,SEPT7,MCM2,SNRPA,POLR2A,XRCC5,ATXN2L,LRPPRC,NUP62,TCOF1,RUVBL2,SCARB1,COPS6,CDK2,HDAC2,DDB1,SSRP1 |
| 2.058e-13 | -29.21 | SUZ12 (SUZ12, polycomb repressive complex 2 subunit) | protein interactions | 23512 | 348 | 111 | 17029 | 2761 |
USP7,SART1,IMMT,COPA,NOP2,XAB2,SUZ12,SF3B1,RBM8A,EBNA1BP2,SNRPD3,UBE2I,SAFB2,RBM4,PABPC4,SF3B2,KRR1,VAV1,MDM2,ATP2A2,EIF4A3,MTA1,NUP107,AQR,CHTOP,DNMT1,TIMM50,MLST8,SRSF10,PRPF19,FYTTD1,SNRNP200,CRNKL1,RNPS1,DNAJC9,BRCA1,DNAJA1,LUC7L,TRIM28,SRSF1,STOML2,CHCHD3,DDOST,LUC7L3,UHRF2,FUS,FAM208A,PDCD11,HDAC2,PPIB,EWSR1,CDC40,PHB2,SRSF6,DHX9,CTCF,SDF2L1,THRAP3,ATP5F1B,EZH1,ERH,DDX56,SMC3,EIF2S2,PPP1R8,KMT5A,RBM34,EFTUD2,ZNF326,H2AFY,YBX1,CREB1,FBL,LUC7L2,RBM15B,LDHB,HP1BP3,PPP1R9B,CSRP1,ERLIN1,SF3B6,GTPBP4,UTP15,ILF3,TUFM,BCLAF1,SRSF5,PLEC,PKM,FXR1,PCGF1,SLTM,SNRPA,PRDX1,XRCC5,CBX3,DDX23,EPRS,UPF1,EPOP,MFAP1,PML,KHSRP,DDX5,RUVBL2,SRSF3,YY1,SNRNP70,RBBP4,PDLIM5,RNF114 |
| 2.151e-13 | -29.17 | BENPORATH_NANOG_TARGETS | MSigDB lists | BENPORATH_NANOG_TARGETS | 915 | 220 | 17377 | 2626 |
CCDC93,H2AFZ,PNISR,GXYLT1,UQCR10,TMEM109,ENSA,GLUD1,MAPK14,PPP1R16B,MAP1LC3B,MYEF2,RBM4,KRR1,PRNP,FANCL,RAP1A,SNUPN,PCNA,DPYSL2,PIK3R2,SRSF4,SLC44A1,DNM2,JOSD1,DRAM2,RPP25,LARS,ERCC1,DPM1,APH1A,FOPNL,KIF15,DDX20,WDHD1,DCUN1D5,DIDO1,ICMT,RAB5B,ARF4,DPYSL3,IWS1,HHEX,EIF4ENIF1,TMED10,NIP7,RPS27A,GRIPAP1,MRPL27,ITGB1,ST3GAL2,RRS1,CLN3,RPS26,UBE2D3,PPP1R2,PHF23,GGA1,ADO,GSPT2,TIA1,ASAH1,MEF2A,PRPF39,SUPT7L,PSMD9,TTF1,ARID1B,APOPT1,MCTS1,FAM192A,RNF121,KLHL5,ZNRF2,SSBP3,MSH2,KNTC1,CARS2,VOPP1,ABHD2,C16orf72,ELL2,SUGP2,PSMA1,USP10,GORASP2,EXOSC9,BCLAF1,EIF2A,CAPZA2,FXR1,KDM3A,EIF4G2,ZNF174,CAND1,GOLGA4,PALB2,QARS,EXOC4,DCAF11,MDH1,RBBP4,EHD4,SNRNP70,C11orf1,CABLES1,USP7,CYLD,TRAF7,TRIP10,SF3B1,XAB2,EIF3D,COPE,WDTC1,TPX2,KLHL18,ORC1,HCFC1R1,PCBP1,RAD23A,OIP5,HNRNPA2B1,FARSA,APLP2,RRN3,ZNF473,KDM2A,NVL,DDA1,CS,INTS12,ZNF226,TALDO1,ZNF770,DVL2,CFL1,ATP6V1G1,PRPF19,CSTF1,SLC39A9,UBQLN4,HMGN4,CDC123,IDH3A,RNF25,E2F3,FRAT2,DNAJC9,NUSAP1,ABHD11,GALK2,DCLRE1C,PKMYT1,FAM72B,GSTCD,SERP1,RAD54B,DDX17,C19orf54,HSPA4,CDC16,H2AFX,RPLP1,NADSYN1,DNAJC2,CDS2,GOLIM4,NUP54,SECISBP2,IFT27,FOXO3,BZW2,HMG20A,MAT2B,PTPN2,GTPBP3,ERH,GART,ADD3,CLIC4,DNAJC8,MZT2A,RPL17,AHSA1,AXIN2,ANP32A,ATG13,CNN2,CITED2,GTF2H2,STAT3,TMEM160,RPRD1A,ZNF202,ABCF2,ILF3,RANGAP1,WDR81,DDX39A,PICALM,SNRPA,DDX23,CBX3,INF2,ATAD2,RPL32,PARG,OAZ2,GLG1,KHSRP,DDX5,ACADM,TAF12,PREPL,WDR62,SAT2,TERF1,IFI16,HIGD2A |
| 2.194e-13 | -29.15 | vpr (p15) | protein interactions | 155807 | 653 | 178 | 17029 | 2761 |
TRIM11,MOGS,CUL1,ABCB10,KIF2C,AGFG1,CCNB1,MAPK14,BIRC2,MIS12,PAPOLA,RPL23A,SF3B2,KIFC1,PA2G4,RAD23B,TRA2B,KIF22,NUP153,CDC25B,PLK1,COPS8,ERCC1,USO1,RBX1,AKT2,HNRNPF,EZR,DDX20,MCL1,ARHGDIB,AURKB,BRCA1,ANLN,SLC25A5,STOML2,ITGB1,KPNA2,ACTB,CHEK2,COPS6,ZMAT3,HDAC2,GEMIN7,DDX58,MAPRE1,EWSR1,POLR2K,GGA1,DNAJB2,PRKAA1,CENPF,ASAH1,COX4I1,CYCS,LMNA,GNS,NFATC3,SMC3,MCM5,CAPZA1,BCL2,CYC1,GEMIN4,ANKHD1,NUP85,FTL,POLR2I,DCAF8,MTA2,PLEC,RIT1,PKM,MAP2K2,MATR3,RHOB,ISG15,FAS,RDH11,SCARB2,KPNA1,POLR2J,DCAF11,YWHAZ,CTSA,GPI,ATP5F1A,CCNB2,RHOG,TCF12,PRKAB1,KARS,SUCLG1,FOXM1,UBR2,MDH2,MYH9,IRF3,BCL2L1,ATP6V1B2,PRKACA,SDHA,RPL11,RAD23A,HNRNPA2B1,DDA1,CLTB,F2R,DCTN1,RPL29,BIRC3,POLR2L,POLR2G,RAB7A,POLR2D,CIRBP,VDAC2,NFATC2,OGDH,VDAC1,SERP1,SRSF1,PPP2CA,HSPA4,PPP2R5A,TULP3,STAT1,H2AFX,NCOA1,MAPK1,TMEM33,MIF,MCM10,SCAMP3,CASP6,CDT1,NUP54,TKT,SLC25A12,ATP5F1B,GGA2,HDGFL2,FOXO3,TFRC,HLA-A,RPA2,GSTK1,PSMD2,RRBP1,GEMIN6,NDUFS8,TAGLN2,PTGES3,CREB1,SPTAN1,TMEM160,TGFB1,TK1,RHOA,ZNF512,PRKAR1B,ILF3,POLR2A,HSPA1B,MAPK3,RPA1,CBX3,MFN2,HLA-B,KPNA4,BIRC5,KHSRP,ACAT1,DDX5,YWHAH,IPO4,DDB1,IFI16 |
| 2.200e-13 | -29.15 | GO_AMIDE_BIOSYNTHETIC_PROCESS | MSigDB lists | GO_AMIDE_BIOSYNTHETIC_PROCESS | 480 | 134 | 17377 | 2626 |
MRPS15,EIF1B,RBM4,MRPL19,PABPC4,SLC25A37,RPL23A,EEF2K,EIF5,MRPL32,PCBP2,LARS,HARS,MRPL12,MRPL43,SLC25A22,SLC25A5,EIF3A,RPL37,RPS27A,RPS14,EIF2D,MRPL27,IARS2,QRSL1,ST3GAL2,MRPL13,RPS26,SLC25A33,RPS15,MRPL9,MRPS2,DHPS,NACA,GSPT2,RPL15,EIF2AK4,MCTS1,EIF2S2,ATIC,EFTUD2,MRPL48,MRPL40,MRPL21,PABPC1,PPA1,EEF1D,CARS2,EIF5A,EIF3L,NOA1,DHX29,RPS10,RPL6,GBA,RPS24,MRPL16,EIF2A,EIF4H,EIF4G2,ABCF1,RPL36,EPRS,MTHFD2,QARS,SAMD8,SMPD4,MRPL3,KARS,RPLP2,MRPL39,EIF3D,SLC25A44,PAIP1,RPL11,MRPL50,FARSA,IARS,MRPL34,MRPS27,RPL29,RPL35,CDC123,RPL38,NDUFA7,POLG2,MRPS14,RPS9,EIF3G,EIF3H,RPSA,EIF3K,MRPL2,DAP3,MRPL55,CERS6,CHCHD1,FTSJ1,RPLP1,PPA2,FAU,SLC25A39,PDF,GCLM,RPS2,MRPL42,MRPS26,SLC25A12,SECISBP2,CHAC2,SLC25A43,GFM2,SLC25A36,GART,GATC,RPL17,RRBP1,MRPL54,RPL19,MRPL11,ST8SIA2,GTF2H2,RPL22L1,SLC25A1,RPL8,TUFM,MRPS10,HAGH,GUF1,RPL27A,TARS,RPL32,SLC25A19,CPEB2 |
| 2.314e-13 | -29.09 | GSE13547_2H_VS_12_H_ANTI_IGM_STIM_BCELL_DN | MSigDB lists | GSE13547_2H_VS_12_H_ANTI_IGM_STIM_BCELL_DN | 172 | 65 | 17377 | 2626 |
UGP2,MDH2,UCK2,NUF2,NANS,FKBP2,STMN1,POLR3K,CCNA2,DUT,KIF22,PLK1,RFC3,CDC123,LAP3,PBK,RAD51AP1,MKI67,CYP20A1,KIF15,RRM2,CKAP2L,AURKB,SLC25A5,ASF1B,PRIM1,SURF4,TIMM17A,NRM,H2AFX,GEN1,STARD3NL,MCM10,MRPL42,CDCA8,TKT,CDCA3,FAM136A,TUBGCP2,SPAG5,PNO1,FBXO5,LYAR,ERH,IRF4,EIF2S2,PPA1,IMPA2,GINS1,PRIM2,PIGT,SSR2,CCDC34,PSMA1,MTX1,DDX39A,HMGN2,SDHB,BIRC5,DCK,DBI,TFDP1,PRMT7,CCNB2,FAM72A |
| 2.385e-13 | -29.06 | negative regulation of cell cycle | biological process | GO:0045786 | 590 | 157 | 17256 | 2622 |
HECA,MAX,GPR132,TSC2,KMT2E,CUL1,CCNB1,MAPK14,FANCI,PRNP,CDK5,CDKN2C,PA2G4,PCNA,PSMD1,CARM1,MLST8,RYBP,CDC5L,PTPRK,PLK1,PLK3,RBX1,EHMT1,NSUN2,MRNIP,RRM2,CDC6,AURKB,BRCA1,CCNF,SOX4,RHEB,DOT1L,HHEX,RPS27A,PSMD8,E2F4,PPM1G,CAB39,STK11,ZNF268,CHEK2,VPS4A,TFDP2,PSMC1,PDCD4,CLSPN,CENPF,PRKAA1,LAMTOR3,TOP2B,EIF2AK4,NOTCH2,PSMD9,CNOT11,CDC73,CNOT3,JMY,DTL,TFAP4,RB1,SMC3,INTS7,FBXO7,MSH2,TIMELESS,BCL2,FBXL7,KNTC1,MCPH1,TERF2,PSMA1,EIF4G2,RHOB,PSMB3,PSMC4,TSC1,LAMTOR4,CNOT6,ZNF830,RBBP4,CDK2,CDKN2A,ZNF207,PRKAB1,CHMP2A,SUZ12,PTTG1,RRAGC,BCL2L1,MDM2,BABAM2,PSMA6,NABP1,CDKN1B,TP53BP2,CEP63,ATF2,CTDSP2,HTRA2,PRPF19,TIMP2,PSMA8,CDC123,BTG2,TAOK1,PSMB7,CUL3,PCGF6,PSMB9,RBL1,PSMD3,H2AFX,GAS2,MIF,CDT1,CDK2AP2,BABAM1,SPDL1,BLM,MAD2L2,FBXO5,CCNK,RPA2,RFWD3,PSMD2,PTEN,CENPJ,PTPN11,NABP2,BRD7,H2AFY,GTSE1,CNOT6L,TGFB1,PPP1R9B,KAT2A,HMGN5,TNFAIP3,PRKDC,TBRG4,PRMT2,MEN1,CBX3,MFN2,CNOT9,TFDP1,PML,E2F1,PKD2,NR2F2,TAF6,HRAS,ESPL1,TERF1,THAP5 |
| 2.456e-13 | -29.03 | CD2BP2 (CD2 cytoplasmic tail binding protein 2) | protein interactions | 10421 | 140 | 59 | 17029 | 2761 |
SART1,PRPF38B,EWSR1,PNISR,TRAF7,SF3B1,SRSF6,DHX8,CSNK2A1,USP39,POMP,SNRPD3,PSMD9,TUBGCP2,LMNA,SF3B2,BANF1,SRSF4,EFTUD2,KIF22,ECD,GEMIN4,AQR,AHCYL1,NAA35,S100A6,PRPF19,CDC5L,SRSF11,UBQLN4,SNRNP200,RBM42,POLK,PSPC1,SNRPB,SMU1,TUBGCP5,CUL3,DDX20,PRPF3,TXNL4A,PRPSAP1,RAB5B,SF3A2,DHX15,GINS4,RAD54B,SRSF1,DDX23,KPNA1,CHD3,MFAP1,U2SURP,PRPF4,DDX5,SNRPG,AKNA,SNRNP70,PRPF4B |
| 2.518e-13 | -29.01 | chromosomal region | cellular component | GO:0098687 | 346 | 104 | 18223 | 2701 |
ZNF207,SKA3,DNMT3A,THOC1,DYNLL1,NUF2,KIF2C,ORC1,SIRT2,CCNB1,MEAF6,MIS12,TERF2IP,HNRNPA2B1,OIP5,PCNA,AHCTF1,KMT5C,SP100,NUP107,NABP1,PDS5B,KIF22,DNMT1,SEH1L,DCTN1,PLK1,ERCC1,FAM172A,WDHD1,WDR82,DCLRE1C,AURKB,MCM2,GAR1,CENPU,DOT1L,PPP2CA,DSN1,FBXO28,PPP2R5A,NSMCE2,H2AFX,BAZ1B,XRCC3,CHEK2,H3F3A,POT1,DYNC1LI2,RAD51D,NSMCE4A,PPP1R12A,HJURP,CDT1,CENPF,DCTN2,CDCA8,SMC6,CTCF,PMF1,SPDL1,BLM,CSNK1A1,NCAPG,PSEN1,CDC73,SPAG5,WRNIP1,RPA2,SMC3,SUV39H2,MCM5,MSH2,NABP2,H2AFY,SS18L1,CENPM,KNTC1,PTGES3,ORC3,NUP85,TERF2,TELO2,PRKDC,RANGAP1,SEPT7,MEN1,PHF6,RPA1,XRCC5,CBX3,KIF18A,UPF1,BIRC5,ZNF330,CDCA5,PML,MBD6,CENPT,NDE1,CDK2,TERF1,PURA,DDB1 |
| 2.621e-13 | -28.97 | GO_REGULATION_OF_PROTEIN_CATABOLIC_PROCESS | MSigDB lists | GO_REGULATION_OF_PROTEIN_CATABOLIC_PROCESS | 377 | 112 | 17377 | 2626 |
ZNF207,ATXN3,SUMO2,CUL1,CSNK2A1,SIRT2,UBQLN2,CCNB1,PRKACA,ANKIB1,PARK7,BCAP31,FBXO22,USP5,RAD23A,UBXN2A,MDM2,PSMD1,PSMA6,CDC42,UCHL5,PIN1,RAD23B,CDKN1B,ANAPC7,RNF19A,TIPARP,SENP1,PDCL3,PLK3,PLK1,UBQLN4,TIMP2,PSMA8,PBK,RAB7A,PSMB7,CUL3,EZR,CDC23,RAB1A,EDEM2,PSMB9,ODC1,CDC16,RPS27A,PSMD8,PSMD3,NSMCE2,AXIN1,ARNTL,SOCS4,ADAM9,XRCC3,ZNF268,TRIM32,CLU,CHEK2,DVL1,GEN1,SMURF1,PSMC1,SMAD4,OAZ1,CSNK1D,SVIP,USP13,GORASP1,GGA1,DNAJB2,UBXN1,CENPF,NKD2,CSNK1A1,PSEN1,PSMD9,RHBDD1,MAD2L2,DDRGK1,FBXO5,RB1,PSMD2,PTEN,LPCAT1,SOCS5,TNFAIP3,GBA,PSMA1,ANAPC2,PTTG1IP,PSMB3,PSMC4,GNA12,HGS,KEAP1,HSPBP1,GOLGA2,CDC27,NSF,OAZ2,PML,FAM83D,RNF14,UBE2C,CD81,RNF139,TERF1,ESPL1,ANAPC4,CDKN2A,FAF1,RNF114 |
| 2.640e-13 | -28.96 | ribonucleoprotein complex assembly | biological process | GO:0022618 | 204 | 73 | 17256 | 2622 |
SART1,NOP2,XAB2,SF3B1,EIF3D,USP39,EFL1,SNRPD3,BRIX1,EDC3,RPL23A,RPL11,SNUPN,ZNHIT6,RPF2,KHDC4,EIF5,STRAP,SRPK2,PRPF19,SRSF10,SNRNP200,SNRPB,CRNKL1,POLR2D,CIRBP,RPL38,DDX20,PRPF3,TXNL4A,LUC7L,CLNS1A,RPSA,EIF3A,SRSF1,GEMIN5,NIP7,RPS14,LUC7L3,EIF2D,ATXN2L,SNRPG,RRS1,GEMIN7,RPS15,SRSF6,AGO2,DHX9,PRPF39,CDC73,PRPF18,MCTS1,GEMIN6,GEMIN4,PTGES3,MRPL11,NSUN4,LUC7L2,PPAN,YTHDC1,DDX28,WDR18,RPL6,RPS10,SRSF5,EIF2A,EIF4H,PATL1,SF3A2,DDX23,RBMX,PRMT7,RUVBL2 |
| 2.656e-13 | -28.96 | interspecies interaction between organisms | biological process | GO:0044419 | 767 | 192 | 17256 | 2622 |
NUP188,PDCD6IP,TSC2,THOC1,UBN1,KDM4A,YTHDC2,TAP1,CUL1,SND1,UBE2I,BECN1,SF3B2,RPL23A,USF1,NUP210,CDC42,IL6ST,ZNF639,SIVA1,AP1M1,AP2B1,NUP153,SEH1L,PCBP2,CARM1,RBX1,SLC25A5,EIF3A,RPL37,RPS27A,RPS14,EIF2D,ITGB1,ATP6V0C,KPNA2,VPS4A,COPS6,RPS26,RTN3,AAAS,DDX58,PPIB,RPS15,DHX9,RPL15,KLC1,CDK13,EIF2AK4,RAB6A,NCKAP1,ITGB5,NUP205,WDR48,MCTS1,CFLAR,TMEM250,TFAP4,RB1,SMC3,BANF1,MDFIC,CPSF4,LRSAM1,NUP85,APOL1,MORC3,EIF3L,ZMYND11,RPL6,RPS10,RPS24,EIF4H,PSMB3,NMT2,ISG15,HMGN2,XRCC5,RPL36,DERL1,SCARB2,KPNA1,SYNCRIP,CCDC86,NUP62,MAP3K5,NUP58,USP7,WASF2,NDC1,CHMP2A,KARS,RPLP2,IVNS1ABP,DYNLL1,EIF3D,RAC1,MON1B,SMARCA4,BCL2L1,IRF3,AP1B1,LYN,PCBP1,CHD1,RPL11,RAD23A,CCNA2,MDM2,SHC1,SP100,NUP107,TAP2,TARDBP,MAVS,RBM15,ABI1,PDCL3,CFL1,RPL29,BRD4,RPL35,RAB7A,SELPLG,PSMB7,RPL38,HTATIP2,NUP155,VDAC1,AZI2,CHMP2B,RAB1A,PSMB9,EIF3G,RPS9,CENPU,RPSA,IDE,CHMP4A,RBL1,HIPK2,STAT1,RPLP1,H2AFX,AP1S1,CHMP4B,SCARB1,MAPK1,XRCC4,AP2S1,CTDP1,RPS2,RAE1,MECP2,NUP54,CBLL1,ARF1,XPR1,TFRC,HLA-A,WWP2,CCNK,GRK2,RPL17,TANK,RPL19,CREB1,STAT3,PACS2,MSH6,RBM15B,TGFB1,RHOA,KAT2A,RPL8,RCOR1,PACS1,RPL27A,FADD,MAPK3,HSPA1B,HLA-B,KPNA4,RPL32,ELMO1,ZC3H7B,PML,CD81,USF2,CHMP7,DDB1,SNAPIN |
| 2.717e-13 | -28.93 | V$NFMUE1_Q6 | MSigDB lists | V$NFMUE1_Q6 | 226 | 78 | 17377 | 2626 |
ZNF207,ASH1L,PRKCSH,PPP1R15B,RAC1,ENSA,USP48,ZADH2,C19orf48,RBM4,RAD23A,USF1,KDM2A,TRA2B,RPAP1,ZBTB22,CHTOP,RNF26,EIF5,CCAR1,SLC39A9,CPNE1,DEAF1,ATP13A1,MIOS,KIF15,ZBED5,VDAC2,NDUFB1,RAB1A,PRPSAP1,RAB22A,DHX15,EIF3A,DAP3,PSMD8,FASTK,LUC7L3,UQCRH,ATP6V0C,ZC3HC1,UBE2D3,PRPF38B,PIGN,ZFP91,NACA,STRN4,TIA1,MYNN,ARF1,CNOT3,XPR1,RPA2,ERH,SMC3,NUS1,SUV39H2,INTS7,RBM3,MAML1,RBM15B,SMC4,NASP,POLK,DCAF8,TOP3A,BCLAF1,UBE4B,SEPT7,EIF4G2,PICALM,NCDN,TSC1,C1orf131,HNRNPH3,ODF2,SLAIN1,YY1 |
| 2.721e-13 | -28.93 | CUL4B (cullin 4B) | protein interactions | 8450 | 345 | 110 | 17029 | 2761 |
USP7,TXN,HNRNPAB,RPLP2,MCCC1,WDTC1,SNRPD3,RBM4,APP,PABPC4,ANKRD39,RPL11,RPL23A,CALM2,SAP130,HNRNPA2B1,OIP5,MDM2,PCNA,DDA1,SRSF4,POP7,TFG,ASB6,SAP30,COPS8,RPL35,RBX1,SNRPB,CUL3,HNRNPF,KIF15,SMU1,TOR1AIP2,WDR82,DNAJA1,DCUN1D5,MCM2,SLC25A5,H2AFV,DHX15,SRSF1,DNAJC10,HNRNPR,RPS14,MYO18A,RPLP1,RWDD4,UHRF2,KPNA2,FUS,SNRPG,COPS6,USP11,HDAC2,TUBB,UBE2D3,RPS2,EWSR1,CDT1,CDCA8,DHX9,RPL15,DCUN1D4,WDR5,TUT4,WDR48,DTL,DDX56,VASP,HUWE1,RTCB,CTPS1,YBX1,AHCY,RBM3,COPS7B,PABPC1,ALDH9A1,LDHB,DCAF6,DCAF8,RPL6,RPL8,TUFM,PSMA1,RPS24,RPL27A,SNRPA,PRDX1,HSPA1B,CAND1,NAP1L1,KPNA4,KPNA1,SYNCRIP,PRDX3,HNRNPH3,DCAF11,FN3KRP,KHSRP,DDX5,WDR76,SRSF3,SNRNP70,WDR62,BRWD3,CDK2,HNRNPDL,DDB1 |
| 3.011e-13 | -28.83 | organic substance transport | biological process | GO:0071702 | 2010 | 419 | 17256 | 2622 |
CCDC93,TMED7,RAB14,NUP188,PDCD6IP,TSC2,TAP1,AP3M2,SYNRG,RIC1,PARK7,RPL23A,CDK5,NAPG,SNUPN,CYB5RL,RABGAP1L,RAB4A,SRSF4,AP1M1,DNM2,AP2B1,NUP153,SLC26A2,SEH1L,SRP72,PGAP2,USO1,TMEM115,OSBP2,ATG9A,AKT2,MCL1,PPFIA3,NUTF2,SLC17A5,ICMT,MCFD2,SLC25A5,RAB22A,SLC50A1,RAB2B,ARF4,PLEKHF2,IWS1,HHEX,MID1IP1,SMAD2,TMED10,RPS27A,RPS14,EIF2D,VIPAS39,ATP6V0C,BTF3,RRS1,ARRB2,NMD3,LONP2,ZMAT3,AAAS,SLC25A33,NXT2,GGA1,SEC61G,DHX9,RAB23,ACAP1,SLC4A2,SLC35B1,TMED3,PSEN1,VPS25,COPG2,NPLOC4,COPB2,ATG4A,SLC38A5,SNX18,FBXO7,TNPO3,ATP6V0A2,MVP,CPSF4,SYTL3,NUP85,TMED2,APOL1,SRSF11,NAGPA,EIF5A,TIMM8B,GCC2,SIGMAR1,EMB,RPS10,RPS24,SSR2,SRSF5,MTX1,TOMM40,PTTG1IP,GOSR1,SFXN5,RHOB,DERL1,SEC31A,SLCO4A1,EPRS,SCARB2,OSBPL11,KPNA1,NSF,PPP3R1,SNX14,NUP58,EXOC3,ANKRD27,NDC1,ABCA3,SARNP,SYS1,RAB11B,RAF1,GPR89A,ANK3,C5orf30,VTI1A,STARD7,MYH9,TBC1D13,SLC35B2,AP1B1,STAM,CD320,RAB21,AHCTF1,TBC1D22A,TBC1D14,NUP107,TNPO2,TAP2,ZC3H3,ATP6V1G1,SNX8,SEC61B,GOPC,RPL38,POLR2D,RNPS1,SLBP,ATP6V0A1,RAB1A,AP4E1,ERC1,SERP1,PEX5,CHMP4A,HSPA4,SEC61A1,VPS26B,RAB24,RPLP1,SEL1L,PITRM1,RPS2,SCAMP3,SRSF6,MECP2,FLOT1,TRAK1,SLC25A12,BTN3A1,IFT27,RAB11A,JAKMIP1,SLC25A36,RPL17,ARF5,RPL19,UPF2,SLC38A10,MTX2,NCOA2,PPP3CA,GUK1,DENND1B,DENND4C,RPL8,RABIF,RAB3IP,DDX39A,MACF1,RPL27A,YIF1A,SLC19A1,KIF18A,HGS,RPL32,LTBP4,SLC38A7,STX18,LRPPRC,PML,KHSRP,SLC25A19,PSAP,YWHAH,VPS29,GPR89B,IPO4,ESYT2,SNAPIN,POLA2,MTX3,COPA,THOC1,NF1,RBM8A,SNX15,ALKBH5,UBE2Q1,SLC29A1,AGFG1,RUFY1,SEC16A,SSR1,RAB8A,NUP210,RAP1A,GOT2,TIMM23,EIF4A3,AP3S2,RAB35,ATG3,PIK3R2,SLC44A1,RP2,SLC35C2,TIMM50,ABCC5,CDC37,VPS13B,FYTTD1,LARS,TLK1,SLC16A7,EZR,SLC25A22,PITPNB,ESYT1,STX16,RAB5B,LSG1,MPC1,OPTN,NECAP2,RPL37,TRAM2,TBC1D17,HSPB11,EIF4ENIF1,TIMM13,GRIPAP1,UEVLD,TIMM29,MIA2,ARRDC1,KPNA2,CLU,VPS4A,CLN3,RPS26,ATP6V0E1,C2CD5,TBC1D12,RPS15,GORASP1,PHB2,CENPF,RPL15,RAB6A,XPO7,RHBDD1,NUP205,CHKA,RINL,KIF13B,ARL6IP1,SLC27A4,GLTP,GLE1,LRSAM1,ATP6V0D1,PREB,ABCC1,KDELR1,ACSL3,RPL6,SYVN1,TMEM241,ZDHHC3,NPIPA1,RPL36,TSC1,GOLGA4,SNAP23,EXOC4,ZDHHC7,SIL1,SLC16A1,NUP62,CTSA,PITPNA,APOL2,SNX27,CHMP2A,CORO7,TOMM20,RPLP2,SLC2A1,COPE,ATP6V1B2,LYN,RPAIN,BCAP31,RPL11,HNRNPA2B1,ANKLE1,ATP6V0B,SAR1A,AKAP8,BCAP29,SCAMP4,CYB5R1,LMAN1,AHCYL1,CLTB,CHTOP,GM2A,CHP1,SNX25,RPL29,NXT1,RPL35,PPT1,RAB7A,SLC26A6,NUP155,BICD2,ERBIN,CHMP2B,RPS9,RHBDF2,RPSA,SRSF1,SURF4,VPS26C,TOMM6,TIMM17A,ARNTL,AP1S1,CHMP4B,SCARB1,NCOA1,SLC22A23,SMURF1,AP2S1,ABCA1,PARD3,CDC40,GOLPH3L,RAE1,NUP54,VPS45,ARFIP2,TIMM21,ARF1,GGA2,AP3S1,MFSD10,TFRC,KLHL20,SLC1A4,SEC24C,RRBP1,SLC35B4,ARHGEF2,ABCD1,STAT3,SLC35A1,CAMK2G,MYO5A,SLC25A1,TGFB1,ZDHHC18,NASP,SNX2,SCFD2,COG1,PNPLA8,SYMPK,MFN2,RAB18,SEC23IP,KPNA4,UPF1,ATP6V1D,PDCD6,GOLGA7,OSBPL8,SNAP29,RBPJ,SPCS3,SRSF3,ATP6V1C1,CHMP7,RAB3IL1 |
| 3.016e-13 | -28.83 | GSE9006_HEALTHY_VS_TYPE_1_DIABETES_PBMC_1MONTH_POST_DX_UP | MSigDB lists | GSE9006_HEALTHY_VS_TYPE_1_DIABETES_PBMC_1MONTH_POST_DX_UP | 189 | 69 | 17377 | 2626 |
SART1,COPA,ADAM10,XAB2,ENSA,GLUD1,DAZAP2,SAFB2,BCAP31,CPNE3,PABPC4,CSDE1,FARSA,NAPG,DPYSL2,TAP2,PCBP2,ORAI2,NRAS,AATF,KLF10,MRPL12,RNPS1,EZR,SOX4,STK17B,BTBD1,STT3A,HNRNPR,CORO1C,SAFB,RNF38,CHEK2,RTN3,ATMIN,NADSYN1,MAPRE1,PRKAA1,PPP3CB,SRRT,PSMD2,RPN1,NDUFV1,MBD2,ARL6IP1,ANXA5,ANP32A,AHCY,RBM3,OSTF1,COPS7B,CSNK1G3,HNRNPM,TMED2,STAU1,PRIM2,PRKDC,WDR18,MRPS10,MATR3,SEC31A,QARS,ODF2,YWHAZ,GPI,SPCS3,RBBP4,TOB1,ADNP2 |
| 3.078e-13 | -28.81 | GSE19888_CTRL_VS_A3R_INHIBITOR_TREATED_MAST_CELL_UP | MSigDB lists | GSE19888_CTRL_VS_A3R_INHIBITOR_TREATED_MAST_CELL_UP | 185 | 68 | 17377 | 2626 |
POLA2,SKA3,HNRNPAB,CKLF,POC1A,TMEM97,TCF19,BCAT2,SNUPN,PPCDC,TXLNA,MRPL34,RPF2,PRADC1,CLN6,PLK1,SNRPB,MRPL12,HNRNPF,CKAP2L,CDCA2,ICMT,MCM2,CCNF,NRM,MPV17,KPNA2,CHEK2,GEN1,E2F2,MRPL13,LRP8,CHID1,COX5B,GALK1,MZT1,DHPS,POLR2K,CDT1,WDR5,RRP36,TFRC,EIF2S2,SUV39H2,NDUFB4,ZDHHC13,KNTC1,GLE1,MYBL2,MFNG,TBRG4,MRPL16,EXOSC9,SNRPA,HAUS8,XRCC5,SLCO4A1,MFAP1,DBI,C4orf46,FAM126A,SSNA1,MDH1,SRSF3,ACADM,CCNB2,TMEM14A,CDK2 |
| 3.106e-13 | -28.80 | GO_POSTTRANSCRIPTIONAL_REGULATION_OF_GENE_EXPRESSION | MSigDB lists | GO_POSTTRANSCRIPTIONAL_REGULATION_OF_GENE_EXPRESSION | 420 | 121 | 17377 | 2626 |
SARNP,RPS6KA1,PPP1R15B,FAM129A,EIF3D,RBM8A,MAPK14,EIF1B,APP,RBM4,PAIP1,PAIP2,HNRNPA2B1,PA2G4,PSMD1,PSMA6,IARS,EIF4A3,METTL14,EXOSC1,TARDBP,EIF5,MTPN,CDC37,LARS,EXOSC6,POLR2G,PSMA8,NCK1,CDC123,AKT2,BTG2,PSMB7,RPL38,CIRBP,POLR2D,SOX4,PRKRA,PSMB9,EIF3G,RPS9,SERP1,EIF3A,EIF3H,EIF3K,MKNK1,EIF4ENIF1,SMAD2,HNRNPR,DGCR8,RPS27A,PSMD8,PSMD3,RPS14,IARS2,RNASEL,SMAD1,MAPK1,PSMC1,NCOR2,UNK,MIF4GD,DHX9,TIA1,SECISBP2,EIF2AK4,THRAP3,RGS2,PSMD9,PARN,SRRT,FOXO3,METTL3,CNOT3,PSMD2,EXOSC7,GATC,DAPK1,AXIN2,DCP1A,ANP32A,YBX1,RBM3,GLE1,CNOT6L,STAT3,PABPC1,NSUN4,EIF5A,TGFB1,EIF3L,ILF3,PSMA1,EIF2AK1,EXOSC9,EIF2A,FXR1,EIF4G2,EIF4H,ABCF1,MATR3,PSMB3,RBM38,DAPK3,MAPK3,PSMC4,TSC1,EPRS,UPF1,SYNCRIP,LRPPRC,PML,E2F1,KHSRP,CNOT6,DTD1,YWHAZ,CPEB2,RNF139,PURA,TOB1 |
| 3.125e-13 | -28.79 | GSE32986_UNSTIM_VS_GMCSF_AND_CURDLAN_HIGHDOSE_STIM_DC_UP | MSigDB lists | GSE32986_UNSTIM_VS_GMCSF_AND_CURDLAN_HIGHDOSE_STIM_DC_UP | 181 | 67 | 17377 | 2626 |
TXN,NQO1,MAGED1,HNRNPUL2,NUF2,BCL2L1,POMP,CNTROB,SLC25A44,FARSA,PSMD1,RNASEK,ATP13A3,AP1M1,NUP153,F2R,TMEM14C,KCNAB2,CPOX,LACTB,NARF,EZR,PSMG1,SMC2,EAF2,PKMYT1,RHEB,RAD54B,BOLA3,KIF18B,RBM47,LIMK1,MRPL27,ADAM9,WSB2,SCAMP3,RHOC,DCTN2,CDCA3,HAUS4,PXMP2,PDXDC1,NUP205,TFRC,RTKN,FBXO5,EBP,CHKA,SLC31A1,RPN1,NDUFB4,FUT8,YIF1B,CENPM,SYTL3,MSH6,PREB,ZFP64,ELL2,TACC1,MAPKAPK3,MRPL16,PCGF1,ODF2,COX8A,SIAH2,WDR76 |
| 3.131e-13 | -28.79 | MORF_RAD23B | MSigDB lists | MORF_RAD23B | 165 | 63 | 17377 | 2626 |
TMEM106C,SEPHS2,KARS,NDUFS1,HNRNPAB,SEC61G,DAP,PDAP1,RAC1,DCTN2,TMEM97,ENSA,COX4I1,CYCS,UBE4A,PSMD9,SDHA,BCAP31,COPB2,MBD4,SF3B2,ATP2A2,UTP18,MTA1,BANF1,RAD23B,BUD31,PPP6C,CYC1,MAML1,EIF5,TMED2,SLC25A1,EBAG9,SP3,POLR2I,DPM1,NSDHL,GMFB,USP10,TMEM147,RAB1A,PRPSAP1,PSMC4,RPA1,STOML2,KIF2A,PDCD6,HSPA4,PRDX3,PSMD8,PARG,MAPK6,PGRMC1,COX5A,MDH1,KPNA2,SNRPG,CLN3,PSMC1,AP2S1,COIL,MYL12B |
| 3.149e-13 | -28.79 | Spliceosome | KEGG pathways | ko03040 | 132 | 56 | 7161 | 1149 |
SART1,PRPF38B,CDC40,THOC1,CHERP,XAB2,SRSF6,SF3B1,RBM8A,USP39,DHX8,SNRPD3,PCBP1,PRPF18,SF3B2,RBM17,CTNNBL1,EIF4A3,SRSF4,EFTUD2,BUD31,TRA2B,AQR,HNRNPM,PRPF19,CDC5L,SRSF10,SNRNP200,SNRPB,PPIE,SF3B6,CRNKL1,LSM8,PRPF3,SRSF5,TXNL4A,SF3A2,SNRPA,DHX15,HSPA1B,DDX23,SRSF1,RBM25,DHX16,LSM6,RBMX,U2SURP,PQBP1,PRPF4,DDX5,SRSF3,SNRPG,ISY1-RAB43,SNRNP70,SMNDC1,DDX42 |
| 3.149e-13 | -28.79 | Spliceosome | KEGG pathways | hsa03040 | 132 | 56 | 7161 | 1149 |
SART1,PRPF38B,CDC40,THOC1,CHERP,XAB2,SRSF6,SF3B1,RBM8A,USP39,DHX8,SNRPD3,PCBP1,PRPF18,SF3B2,RBM17,CTNNBL1,EIF4A3,SRSF4,EFTUD2,BUD31,TRA2B,AQR,HNRNPM,PRPF19,CDC5L,SRSF10,SNRNP200,SNRPB,PPIE,SF3B6,CRNKL1,LSM8,PRPF3,SRSF5,TXNL4A,SF3A2,SNRPA,DHX15,HSPA1B,DDX23,SRSF1,RBM25,DHX16,LSM6,RBMX,U2SURP,PQBP1,PRPF4,DDX5,SRSF3,SNRPG,ISY1-RAB43,SNRNP70,SMNDC1,DDX42 |
| 3.167e-13 | -28.78 | GSE23321_EFFECTOR_MEMORY_VS_NAIVE_CD8_TCELL_DN | MSigDB lists | GSE23321_EFFECTOR_MEMORY_VS_NAIVE_CD8_TCELL_DN | 173 | 65 | 17377 | 2626 |
RHOG,NUP188,HNRNPAB,GNPDA1,URB2,PPP1R15B,RBM8A,PLAGL2,CSNK2A1,NIPA2,EBNA1BP2,ADPGK,ZNF267,BRIX1,RBM4,PABPC4,KRR1,TET3,RAB21,RRN3,IARS,TXLNA,TRA2B,LRRC59,RYBP,PPIF,NXT1,BTG2,VDAC2,POLR2D,PITPNB,ARL5B,GEMIN5,NIP7,MAFK,SOCS4,SEL1L,BEND3,RRS1,PITRM1,PDCD2L,TMEM33,POLR2K,NUP54,QSOX2,LMNA,TFRC,IRF4,VMP1,ARHGEF2,DDX31,B3GALT6,PIGT,AMD1,ABCF1,UTP20,ADSS,KPNA1,KPNA4,UAP1,NFIL3,LRPPRC,NAA20,GPATCH4,NIPA1 |
| 3.167e-13 | -28.78 | cellular catabolic process | biological process | GO:0044248 | 1755 | 374 | 17256 | 2622 |
PDCD6IP,HEXB,CUL1,GLUD1,NHLRC3,GYG1,CCNB1,UBE2I,OAT,PARK7,FBXO22,PABPC4,RPL23A,CDK5,PSMD1,RAD23B,MECR,AP2B1,CISD2,PCBP2,USP34,ATG9A,TOPORS,SUPT20H,USP22,AURKB,AMDHD2,CCNF,PLEKHF2,RPS27A,PSMD8,RPS14,AXIN1,PRDX5,ATE1,MLYCD,VIPAS39,DHTKD1,KLHL42,SMG9,FBXL3,ARRB2,LONP2,PFKP,MUT,PHF23,GSPT2,ADO,PRKAA1,RAB23,TATDN3,KCTD17,ZNRF3,PSMD9,PARN,PSEN1,METTL3,VPS25,CNOT3,NPLOC4,ATG4A,GNS,RNF121,PDXP,EXOSC7,ZNRF2,FBXO7,BDH1,FBXL7,PABPC1,PHKG2,CPQ,RB1CC1,MAN1B1,RPS10,USP10,RPS24,EXOSC9,PKM,TOMM40,PATL1,PSMB3,DERL1,CAT,KPNA1,DCAF11,USP32,CNOT6,SMPD4,GPI,WIPI2,HEXA,RNF139,SNX14,NUDT3,ATXN3,UBR2,PTTG1,VTI1A,ADPGK,STAM,ABHD16A,NUDT19,DECR1,SIAH1,MTA1,UCHL5,DUT,LPIN2,SOCS6,NSFL1C,ANAPC7,TTC3,RNASEH2A,CLN6,ENPP4,ULK3,SEC61B,RPL38,POLR2D,RNPS1,CUL3,RAB1A,CDC23,PSMB9,PPP2CA,ANKZF1,ALDH3B1,CDC16,CHMP4A,HINT1,RAB24,LSM6,NT5C3B,RNF38,RPLP1,SEL1L,TRIM32,USP13,GALK1,RPS2,MANBA,ATG2B,SDF2L1,UBE4A,NEIL2,TUT4,WWP2,CAPN2,PSMD2,RPL17,CRAT,PPP1R8,DCP1A,GTSE1,LTN1,RPL19,UPF2,CNOT6L,FBXL19,PACS2,TNFAIP3,GALC,RNASEH2C,TRIR,USP42,RPL8,LDHA,FBXO9,ANAPC2,PDE3B,RPL27A,MARK2,ECH1,PRDX1,SH3GLB1,FBXO21,SGSH,KEAP1,HGS,RPL32,PRDX3,TATDN2,ACOX1,PML,KHSRP,PPP1R11,DDX5,HMGB2,WDR91,WDR45B,ANAPC4,DDB1,FAF1,SNAPIN,ADA2,GNPDA1,RBM8A,MCCC1,CSNK2A1,UBE2Z,SND1,SIRT2,UBQLN2,USP48,MAP1LC3B,BECN1,BIRC2,RNF103,EDC3,BCAT2,PCYOX1L,MBD4,TET3,RAB8A,GOT2,EIF4A3,RAB35,ATG3,METTL14,SLC44A1,HADHB,OGG1,DRAM2,WDR41,PLK1,EXOSC6,RBX1,USP21,OPTN,RPL37,TBC1D17,ARRDC1,STK11,CHEK2,CLU,VPS4A,CLN3,NUDT11,NGLY1,RPS26,PSMC1,CAPN1,UBE2D3,RMND5A,RPS15,TMUB1,UBXN1,RPL15,PM20D2,THRAP3,CNOT11,EPHX2,RHBDD1,PRPF18,DTL,TIGAR,VMP1,EI24,SLC27A4,AHCY,ACAD8,ZRANB1,LRSAM1,ABHD2,ERLIN1,NUDT4,RPL6,GBA,PSMA1,UBE4B,SYVN1,ARMC8,RMC1,ISG15,RPL36,PSMC4,CDC27,KLHL15,SIAH2,CTSA,DNPH1,ECPAS,USP7,CHMP2A,PRKAB1,TOMM20,CYLD,RPLP2,DYNLL1,PAIP1,RPL11,RAD23A,USP5,CSDE1,UBXN2A,PSMA6,MDM2,KIF14,EXOSC1,GM2A,SPSB3,HTRA2,RLIM,CHP1,PRPF19,SNX25,RPL29,UBQLN4,RPL35,POLR2G,PSMA8,HPDL,PPT1,RAB7A,PSMB7,OGDH,VDAC1,CHMP2B,EDEM2,TOLLIP,RPS9,USP36,BTBD1,RPSA,PON2,DNAJC10,IDE,UBXN2B,TOMM6,PSMD3,ARNTL,CHMP4B,USP11,SMURF1,LTA4H,AP2S1,CHID1,TRIP12,DAP,CHAC2,CSNK1A1,DNAJB9,CTSS,KLHL20,PELO,ATG13,ABCD1,RNF5,TGFB1,SAMD4B,RFFL,WDR81,PNPLA8,HAGH,NEU1,TFEB,HSPA1B,MFN2,CNOT9,MTMR3,CTSL,UPF1,PLAA,SNAP29,CTBS,ACAT1,USP20,ACADM,TATDN1,UBE2C,PGAM1,GCSH,IFI16 |
| 3.180e-13 | -28.78 | proteasome-mediated ubiquitin-dependent protein catabolic process | biological process | GO:0043161 | 308 | 97 | 17256 | 2622 |
ATXN3,UBR2,PTTG1,CUL1,NHLRC3,SIRT2,UBQLN2,CCNB1,UBE2I,BIRC2,RNF103,RAD23A,UBXN2A,PSMA6,PSMD1,MDM2,SIAH1,MTA1,KIF14,RAD23B,NSFL1C,ANAPC7,SPSB3,PCBP2,RLIM,PLK1,SEC61B,RBX1,PSMA8,CUL3,PSMB7,TOPORS,AURKB,CCNF,EDEM2,CDC23,PSMB9,BTBD1,ANKZF1,DNAJC10,CDC16,RPS27A,PSMD8,UBXN2B,PSMD3,AXIN1,ARNTL,RNF38,SEL1L,KLHL42,FBXL3,SMURF1,ARRB2,PSMC1,UBE2D3,RMND5A,TMUB1,UBXN1,KCTD17,UBE4A,CSNK1A1,PSMD9,DNAJB9,NPLOC4,WWP2,PSMD2,RNF121,KLHL20,ZNRF2,GTSE1,LTN1,FBXL7,FBXL19,RNF5,ERLIN1,MAN1B1,RFFL,PSMA1,FBXO9,ANAPC2,UBE4B,SYVN1,ARMC8,PSMB3,PSMC4,DERL1,PLAA,CDC27,KLHL15,PML,DCAF11,ECPAS,UBE2C,RNF139,ANAPC4,DDB1,FAF1 |
| 3.236e-13 | -28.76 | WANG_TUMOR_INVASIVENESS_UP | MSigDB lists | WANG_TUMOR_INVASIVENESS_UP | 355 | 107 | 17377 | 2626 |
IER2,TOMM20,H2AFZ,HNRNPAB,RPLP2,PPP1R15B,PTTG1,UBE2Q1,GLUD1,MAP1LC3B,PCBP1,SDHA,KCMF1,HNRNPA2B1,PCNA,CDC42,TARDBP,RNASEH2A,STRAP,HTRA2,TACC3,CCT2,MAPRE2,RPL35,BRD4,SEC61B,EID1,RBX1,RAB7A,VDAC2,CIRBP,EZR,PSMG1,PITPNB,NUTF2,SLC25A5,FKBP3,TRIM28,EIF3H,PAF1,HSPA4,ATP1A1,HINT1,BRD2,HNRNPR,PSMD3,RPS14,PRDX5,STAT1,STK11,KPNA2,FAU,TUBB,HSPH1,DNAJC2,B4GALT5,NACA,UBXN1,CDCA3,TKT,CTCF,GTF3A,PIP4K2A,NDUFS4,WWP2,RPA2,SUB1,RPN1,EIF2S2,ARPC5,CAPZA1,BRD7,YBX1,KIFAP3,RPL19,CNN2,PABPC1,CAMK2G,S100A6,SAMD4B,PPAN,TSTA3,AMD1,TEX10,RPL8,RPL6,ARHGEF12,SEPT7,EIF4G2,EIF4H,ABCF1,GNAS,MTMR3,NAP1L1,PCM1,KPNA1,RPL32,ERGIC3,DBI,COX8A,HMGB2,SSNA1,DDX5,SRSF3,ATP6V1C1,FAF1,EGLN1 |
| 3.303e-13 | -28.74 | regulation of cellular macromolecule biosynthetic process | biological process | GO:2000112 | 4170 | 782 | 17256 | 2622 |
ZBTB10,KDM4A,HEXB,XIAP,CCNL2,EDRF1,RBM4,ZNF275,CDK5,USF1,PSMD1,CIPC,THAP4,DNM2,CRY2,FNIP2,ECD,SENP1,PLK3,ZNF672,ZNF559,AATF,GABPA,EHMT1,WDHD1,MIER2,TOPORS,ARF4,STOML2,BRMS1,BOLA3,SMAD2,RPS27A,ZNF689,AXIN1,PRDX5,OGT,VIPAS39,RNASEL,TRIM52,TFDP2,SMAD1,E2F2,ZNF75A,PDCD4,ZNF720,SSRP1,HIVEP3,DHX9,EZH1,EIF2AK4,PSMD9,PARN,CDC73,MCTS1,DDRGK1,TFAP4,SMC3,MEGF8,PHF14,ZNF326,FOXN2,MYDGF,PABPC1,NUP85,NSUN4,CYFIP1,IFRD1,ETV3,FOXK1,RB1CC1,ZMYND11,MTA2,GTPBP4,MYBL2,ITM2A,BCLAF1,CBFA2T2,ELK1,EIF4H,PDLIM1,ETS2,SETD3,CNOT6,ZNF830,SGF29,RNF139,EGLN1,ZNF207,RHOG,ZNF296,KARS,SARNP,TRERF1,IVNS1ABP,UBR2,PTTG1,WDTC1,CREBL2,ZNF267,INO80E,SAFB2,RCOR3,TCF19,APP,AHCTF1,ZNF420,SP100,ZKSCAN1,MTA1,GMEB1,NUP107,ZNF226,MAVS,ATF2,RBM15,ZC3H3,RPRD1B,CGGBP1,CPNE1,PSRC1,POLR2L,EID1,KAT7,WBP2,RPL38,POLR2D,CIRBP,E2F3,HTATIP2,MEF2D,DDX17,TAF2,PPP2CA,CHCHD3,HIPK2,TICAM1,FUS,ZBTB11,LRP8,USP13,COMMD10,ZNF786,ZNF445,ZFP91,HABP4,TRAK1,JMJD6,GMCL1,ABHD14B,WDR5,ETS1,NEXMIF,ZNF92,PPP1R3B,ZBTB45,PSMD2,SUV39H2,PPP1R8,PRDM4,ZNF260,LTN1,ZNF710,GTF2H2,MED22,PDPK1,PPP3CA,TNFAIP3,ZNF512,ZP3,PICALM,ZNF862,ZNF180,KEAP1,GPS2,PITX1,LRPPRC,PML,HMGB2,CD81,PARP10,IGBP1,USF2,YWHAH,THAP5,FAF1,AGRN,THOC1,AAMDC,GPBP1L1,TRIM11,PPP1R15B,FAM129A,RBM8A,CSNK2A1,SND1,BIRC2,CREM,PRNP,LIN9,TET3,PCNA,GLIS2,ZNF639,ETV6,PIK3R2,NOC2L,EIF5,MYBL1,MTPN,CCAR1,RYBP,PTPRK,PLK1,SP3,CELSR2,RBX1,PBXIP1,BAZ2A,ZBED5,MRPL12,EZR,CDC6,UBE2V1,LRP5,PBRM1,EAF2,BRCA1,USP21,TONSL,CHD3,ZNF367,E2F4,DVL1,ZNF45,BEND6,FAM208A,POT1,ZNF564,FUBP1,LZTR1,PHB2,CENPF,CTCF,CHCHD2,CDK13,DNAJB1,PPP3CB,RLF,ASXL2,CNOT11,CRLF3,ARID1B,LRRC14,SUB1,RB1,MLX,MED8,MBD2,SSBP3,ZNF746,CTR9,TIMELESS,MDFIC,AFF1,RBM3,ICE2,GLE1,MAML1,PREB,TRAPPC9,LDB1,UTP15,KRAS,EIF2AK1,RTF1,ZNF761,NFATC2IP,EIF4G2,IRF5,ZNF174,PSMC4,RXRB,SYNCRIP,NLRC5,TBPL1,PRMT7,RUVBL2,USP7,CYLD,TRAF7,ARID2,FOXM1,DYNLL1,ZNF416,DUSP22,PCBP1,COMMD8,ZNF121,VAV1,CSDE1,NRF1,ZBTB21,PSMA6,ZNF473,MDM2,KMT5C,ZNF302,PIN1,TARDBP,STRAP,SAP30L,ZNF583,DVL2,KDM3B,POLR2G,ZNF780B,PSMA8,BTG2,PPIE,NFATC2,KDM1B,EIF3H,SCAP,ZNF700,RBL1,MAFK,PSMD3,ZNF436,UHRF2,DNAJC17,NCOA1,H3F3A,SMAD4,ZNF146,BCL2L12,SLC30A9,CTDP1,UNK,MIF4GD,MTERF1,DAP,CDT1,AGO2,ARID5A,GTF3A,HMGN3,NKRF,CDK11B,PAGR1,FZD6,WRNIP1,PTPN2,IRF4,SS18L1,PTGES3,RBM15B,RPRD1A,RHOA,HMGN5,BTAF1,PRKDC,ZNF202,ZMYM5,PCGF1,TRIM26,BIRC5,TWSG1,L3MBTL3,TFE3,CDCA7L,BBX,E2F1,PKD2,RBPJ,TAF12,NR2F2,HIPK3,IFI16,TXN,ZNF496,H2AFZ,MAX,TSC22D3,CXXC1,YTHDF3,UBE2I,EIF1B,COMMD6,MYEF2,PARK7,GLMP,PA2G4,NOL11,FIZ1,ZNF200,TAF5L,SMARCE1,DNMT1,ZNF800,CDC5L,SRSF10,ZNF524,KLF10,AKT2,ELOA,DDX20,AURKB,USP22,RFC2,CBFB,ZMYM3,IWS1,DOT1L,MAP3K4,HHEX,MKNK1,BRD2,PSMD8,RPS14,BTF3,ARRB2,TRAF5,ZNF598,CCDC59,HDAC2,PTOV1,SVIP,DDX58,HSPH1,EWSR1,POLR2K,CHTF18,PRKAA1,NOTCH2,PMF1,SUPT7L,ZNF79,PSEN1,ZNF518A,METTL3,VPS25,YY1AP1,CNOT3,JMY,CFLAR,LHX8,MEX3C,KLF16,HDAC7,DAPK1,TNRC18,EEF1D,TERF2,EIF5A,PHF10,ZNF84,ELL2,ZNF574,USF3,EXOSC9,ARID1A,ADRB2,C9orf40,CYFIP2,FXR1,KDM3A,MAP2K2,CCT8,PSMB3,PHF6,XRCC5,CAT,PFDN5,EPRS,ZNF777,SERTAD2,GOLGA2,EPOP,ZFP92,RBMX,QARS,MED15,CEBPG,PPP3R1,PIAS2,TCOF1,YY1,MAP3K5,RNF14,CDK2,CDKN2A,ZNF511,DNMT3A,ATXN3,RWDD1,ZBTB37,RPS6KA1,RAF1,SUZ12,EIF3D,RAC1,MAGED1,PAIP2,TERF2IP,SPINDOC,CCNA2,ZNF75D,SHC1,KDM2A,UCHL5,LPIN2,MRPS27,CDKN1B,CDK12,SAP30,CCT2,BRD4,RFC3,ERF,CDC123,DRAP1,CUL3,ELP4,EDF1,H2AFV,PSMB9,ERC1,TRIM28,SERP1,CENPU,PRDM11,SUPT16H,EIF3K,VEZF1,ZNF282,HINT1,CERS6,SAFB,STAT1,H2AFX,ATF6,TRIM32,BEND3,EYA2,ATMIN,RHEBL1,POU3F2,NCOR2,DEPDC1,MECP2,TCF3,ARGLU1,SECISBP2,MYNN,BLM,POFUT1,FOXO3,HMG20A,MAD2L2,WWP2,GTF2F1,CCNK,PTEN,ELP5,CARF,CITED2,CREB1,CNOT6L,NCOA2,TSHZ1,ZFP64,KAT2A,NEK7,WDR18,ILF3,PARP4,RFXANK,KLF6,COMMD4,FADD,POLR2A,CBX3,PRDX3,ZHX1,TFDP1,KHSRP,DDX5,BRWD3,TAF6,CPEB2,PURA,FAM83G,RORB,ZBED3,CCNC,ZNF76,IER2,NOP2,HNRNPAB,UBN1,KMT2E,DNAJC24,PTP4A3,ZNF107,SIRT2,TAF6L,COMMD5,MAPK14,SNAPC4,ZNF696,EIF4A3,JAZF1,METTL14,PHTF1,SRI,ZBTB22,TCEA1,OGG1,ARID4A,CARM1,TRIM14,ELOF1,DEAF1,TRIM8,NCK1,VHL,RIOX2,RRM2,SOX4,KMT2C,ASF1B,GEMIN5,UBTF,PAF1,EIF4ENIF1,BRWD1,PQBP1,BAZ1B,ZNF268,CHEK2,CLU,PSMC1,UBE2D3,PPP1R12A,ZNF768,NACA,CIB1,MED13L,TIA1,MEF2A,THRAP3,RGS2,TTF1,SRRT,LYAR,NFATC3,ZNF449,MED10,BUD31,ZNF335,BCL2,YBX1,ACAD8,MCPH1,ZNF189,HP1BP3,VOPP1,CREG1,ERLIN1,CIC,RPL6,GBA,PSMA1,EIF2A,SLTM,DAPK3,CAND1,TSC1,NFIL3,NUP62,ZFP90,RBBP4,HNRNPDL,TOB1,N4BP2L2,SMARCD1,ADNP2,ZBTB24,TCF12,MBD1,ASH1L,MPHOSPH8,SMARCA4,PLAGL2,NSD3,IRF3,ORC1,CHD1,MXD1,PAIP1,MEAF6,HNRNPA2B1,SAP130,RRN3,NVL,AKAP8,CHTOP,F2R,UTP4,ZNF770,RLIM,CHP1,MOSPD1,POU2AF1,FAM172A,ZNF500,RNF25,PCGF6,PSMB7,ATXN1,BOLA1,GLO1,ERBIN,MBD3,RPS9,ZNF317,TAB2,HNRNPR,STAT6,TULP3,ARNTL,AKNA,SMURF1,MAPK1,BRD9,CBX4,NAT14,DNAJC2,ZNF316,EYA1,SCYL1,DBF4,KLF13,PAWR,MXD4,FBXO5,FASTKD3,KMT5A,PELO,NABP2,H2AFY,ANP32A,BRD7,ARHGEF2,STAT3,TGFB1,SAMD4B,PHF20L1,COA3,DCAF6,HMGN1,PSPC1,MIER1,RCOR1,PRMT2,MEN1,ZNF407,CDK11A,MAPK3,TFEB,HSPA1B,CNOT9,LEMD2,UPF1,ATAD2,KMT2B,ZRANB2,CENPT,ZMIZ1,HRAS,TERF1 |
| 3.354e-13 | -28.72 | CHANG_CYCLING_GENES | MSigDB lists | CHANG_CYCLING_GENES | 138 | 56 | 17377 | 2626 |
SKA3,MZT1,HJURP,DEPDC1,FOXM1,POC1A,PTTG1,CENPF,TPX2,RRM1,CDCA8,KIF23,NUF2,SPAG5,KIFC1,LYAR,PCNA,CCNA2,MCM5,GTSE1,KIF22,CENPM,TACC3,SMC4,PLK1,MND1,PSRC1,PRIM2,RAD51AP1,PBK,AMD1,CKAP2L,RRM2,NUSAP1,RANGAP1,CDC6,FAM72B,ANLN,CCNF,RFC2,ASF1B,PRIM1,ANKRD10,ATAD2,BIRC5,PRPS2,CDCA5,FAM83D,E2F1,H2AFX,ANP32E,MBOAT1,WDR76,CCNB2,UBE2C,TUBB |
| 3.384e-13 | -28.71 | VDAC1 (voltage dependent anion channel 1) | protein interactions | 7416 | 274 | 93 | 17029 | 2761 |
NDUFA5,COX15,IMMT,TOMM20,TXN,RAF1,COPE,CLCC1,BCL2L1,SAFB2,BCAP31,IARS,HADHB,RPN2,BCAP29,CISD2,TECR,CHTOP,ATF2,FGFR1OP2,GPX4,BAK1,PPIF,LARS,RPL35,RAB7A,MRPL12,VDAC2,RNPS1,DNAJC9,MCL1,SLC25A5,H2AFV,STOML2,SUPT16H,SUGP1,CHCHD3,ATP1A1,DDOST,SAFB,COX5A,CHMP4B,MAPK1,SSRP1,NDUFV2,EWSR1,NDUFS1,PHB2,TKT,CYCS,COX4I1,ATP5F1B,ARF1,THRAP3,SCYL2,PIP5K1C,NDUFS4,KIF5B,ERH,RPN1,NDUFB4,BANF1,RTCB,H2AFY,BCL2,CYC1,FBL,ATP6V0D1,PABPC1,TMX1,ABCC1,HP1BP3,ERLIN1,SF3B6,LDHA,ADRB2,ATP5MF,TOMM40,CCT8,MAPK3,CBX3,RPL36,XRCC5,EPRS,NAP1L1,MAGT1,PRDX3,PGRMC1,YWHAZ,ACADM,ATP5F1A,CDK2,HNRNPDL |
| 3.760e-13 | -28.61 | PDHA1 (pyruvate dehydrogenase E1 alpha 1 subunit) | protein interactions | 5160 | 308 | 101 | 17029 | 2761 |
IMMT,PDCD6IP,SARNP,HNRNPAB,ADD1,COPA,THOC1,MDH2,HNRNPUL2,RBM8A,SND1,SEC16A,SDHA,RBM4,PARK7,CALM2,PDK2,RBM23,ATP2A2,IARS,NUP107,RPN2,CHTOP,LRRC59,PRPF19,CCT2,USO1,RPL35,SEPT9,PPT1,RAB7A,VDAC2,CUL3,NLN,DNAJA1,OGDH,RAB1A,VDAC1,LUC7L,PDHX,GINS4,EIF3A,STOML2,SUPT16H,CHCHD3,MRPL2,ATP1A1,DDOST,TMED10,SAFB,CORO1C,PQBP1,H3F3A,MRPL13,ANXA11,FUBP1,PPP1R2,SCAMP3,AGTRAP,BABAM1,FLOT1,CHCHD2,THRAP3,RAB11A,SRRT,TFRC,LMNA,RPN1,NDUFV1,HUWE1,RRBP1,H2AFY,PABPC1,EEF1D,LDHB,HP1BP3,PPP1R9B,RHOA,PSPC1,MTA2,LDHA,RANGAP1,ADRB2,PLEC,TOMM40,SYMPK,CDK11A,CCT8,NCDN,PHF6,RPA1,SDHB,RPL32,GOLGA2,HNRNPH3,LRPPRC,ACAT1,NUP62,RUVBL2,HNRNPDL,ZC3HAV1 |
| 3.850e-13 | -28.59 | DAIRKEE_TERT_TARGETS_UP | MSigDB lists | DAIRKEE_TERT_TARGETS_UP | 333 | 102 | 17377 | 2626 |
RWDD1,FAM207A,RAC1,PTTG1,UCK2,KIF2C,CNTROB,IKBIP,HCFC1R1,GNB2,BCAT2,PRNP,EEF2K,SEC11A,CDKN2C,FARSA,SIVA1,PIN1,RCSD1,RAD23B,MECR,ZNF226,CDC25B,CORO1A,CLTB,FAM3A,ZNRD1,DNMT1,PPIF,RPL29,RPL35,DRAP1,SLC26A6,MRPL12,OGDH,OGFR,EIF3G,STOML2,DAP3,DDOST,LSM6,RPS14,PQBP1,COX5A,CHMP4B,PPP2R2D,CAPN1,C19orf53,MRPS2,UBXN1,TKT,NUP54,ARFIP2,RPL15,HMGN3,JMJD6,APOPT1,EBP,C12orf10,NDUFA2,SLC38A5,GLTP,PCYT2,MRPL48,GEMIN4,CNPY3,ATP6V0D1,JMJD4,TELO2,TK1,NOA1,NQO2,ILF3,MFNG,RFXANK,RPS10,PSMA1,MTX1,LY6E,RHOT2,ARPC1A,SNRPA,RPL36,PLD3,ZNF777,LTBP4,BIRC5,QARS,RBMX,DBI,PGRMC1,FAM83D,KHSRP,PPP1R11,SSNA1,TCOF1,EHD4,SNRNP70,PLOD3,TAF6,DEF6,HIGD2A |
| 3.940e-13 | -28.56 | MOREAUX_MULTIPLE_MYELOMA_BY_TACI_DN | MSigDB lists | MOREAUX_MULTIPLE_MYELOMA_BY_TACI_DN | 150 | 59 | 17377 | 2626 |
NADSYN1,GLT8D1,PPP1R12A,DBF4,KLF13,SMARCA4,RACGAP1,EBNA1BP2,IP6K2,TMEM165,MRPL19,PAIP1,PAPOLA,MBD4,SF3B2,SLC25A36,FANCL,MRPL50,IARS,EFTUD2,NAA50,FEM1B,DDX31,MINPP1,TIMM50,TSHZ1,CCT2,ERCC1,NASP,LAP3,DHX29,PRKDC,NOL8,MRPL43,ILF3,CDC23,MCM2,COMMD4,MATR3,EIF3G,BTBD1,PSMC4,KRIT1,GEMIN5,TAF2,KEAP1,CHMP4A,PDCD6,C1orf131,PFDN4,PSMD8,ZNF367,CHCHD1,SLC16A1,NCLN,RUVBL2,TATDN1,TERF1,GCSH |
| 3.992e-13 | -28.55 | transport | biological process | GO:0006810 | 4204 | 787 | 17256 | 2622 |
CCDC93,TMED7,RAB14,TSC2,ADD1,ABCC10,HEXB,TGOLN2,SYNRG,CMTM6,FBXO22,RPL23A,CDK5,NAPG,PSMD1,RABGAP1L,SRSF4,ATP13A3,AP1M1,DNM2,UPRT,NUP153,KCNAB2,BAK1,PGAP2,RHOBTB3,TMEM115,NRAS,KIF15,MCL1,PPFIA3,NUTF2,ICMT,RAB22A,SLC50A1,ARF4,PLEKHF2,STOML2,MID1IP1,SMAD2,RPS27A,LIMK1,MYO18A,COX5A,VIPAS39,ATP6V0C,TFDP2,LONP2,AAAS,ANXA11,SLC25A33,NXT2,GGA1,SEC61G,CCZ1,DHX9,RAB23,SLC4A2,TMED3,PSMD9,COPB2,ATG4A,TMEM179B,GNS,CD59,EIF2S2,SLC38A5,RIMS3,FBXO7,TNPO3,GEMIN4,CPSF4,MVP,NUP85,PPP6R1,SRSF11,NAGPA,CYFIP1,TIMM8B,MAPKAPK3,ERO1A,RPS10,SSR2,SRSF5,MTX1,SFXN5,ABCF1,RHOB,CYB5A,MAGED2,SCARB2,OSBPL11,KPNA1,NDE1,SNX14,NUP58,ALS2,EXOC3,RHOG,ANKRD27,ABCA3,SARNP,ACTR3,ANK3,C5orf30,VTI1A,STARD7,MON1B,MYH9,TBC1D13,NIPA2,NIT2,SLC35B2,STAM,CPNE3,REPS1,APP,CLUAP1,RAB21,AHCTF1,ATP2A2,SH3BP1,TBC1D22A,TBC1D14,NUP107,CLCN6,MICU2,ATF2,ZC3H3,DCTN1,ATP6V1G1,SNX8,ENPP4,CPNE1,SEC61B,GOPC,RPL38,POLR2D,RNPS1,ATP6V0A1,HTATIP2,DNAJA1,RAB1A,KIF2A,ALDH3B1,PEX5,SEC61A1,VPS26B,CORO1C,RPLP1,PDXK,SNRPG,PITRM1,LRP8,TUBB,RPS2,ANXA6,SRSF6,HABP4,FLOT1,TRAK1,BTN3A1,JMJD6,ATP5F1B,IP6K2,IFT27,SLC25A43,PSMD2,ADD3,CLIC4,HUWE1,ARF5,ANXA5,GEMIN6,GTF2H2,TPCN1,S100A6,SPTAN1,PPP3CA,GUK1,MRS2,HEBP2,MTMR12,RAB3IP,DDX39A,PICALM,SLC19A1,KIF18A,MAGT1,FAM3C,LRPPRC,PML,LY75,SLC25A19,SSNA1,PSAP,CD81,USF2,YWHAH,SNAPIN,COX15,THOC1,SNX15,RBM8A,CDC42SE2,SEC16A,RUFY1,GIT2,KCMF1,SSR1,RAB8A,NUP210,TIMM23,PIK3R2,SLC44A1,TXLNA,ZFYVE27,ABCC5,VPS13B,CDC37,SNRPB,TLK1,CYSTM1,EZR,LRP5,ESYT1,STX16,RAB5B,LSG1,OPTN,NECAP2,TRAM2,TBC1D17,TIMM13,AGPAT2,GRIPAP1,ARRDC1,KPNA2,ACTB,PIEZO1,DVL1,CLN3,C2CD5,GEMIN7,PHB2,CENPF,NKD2,LAMTOR3,KLC1,ASAH1,COX4I1,RACGAP1,CDK13,RAB6A,NCKAP1,PPP3CB,RINL,VMP1,KIF13B,ARL6IP1,SLC27A4,GLE1,LRSAM1,PREB,ABCC1,CYTH1,TRAPPC9,ACSL3,EIF2AK1,ARPC1A,ARMC8,APPL1,NPIPA1,ZDHHC3,NMT2,BBS12,PSMC4,RPL36,GOLGA4,PCM1,SNAP23,COX7A2L,ZDHHC7,SIL1,ATP5F1A,UNC13C,NIPA1,RPLP2,DYNLL1,SLC2A1,COPE,ZFYVE21,ATP6V1B2,LYN,BCAP31,RPAIN,RPL11,VAV1,ATP6V0B,PSMA6,BRPF3,BCAP29,CORO1A,LMAN1,AHCYL1,GM2A,SNX25,SLC39A9,PPIF,ARHGAP17,CLCN3,RPL29,TIMP2,RPL35,PPT1,PSMA8,RAB7A,PPIE,SLC26A6,MTMR6,NUP155,CHMP2B,VDAC1,RHBDF2,TMEM201,RPSA,SRSF1,ATP1A1,PSMD3,TIMM17A,TOMM6,DNAJC17,AP1S1,CHMP4B,NCOA1,SLC22A23,LTA4H,AP2S1,CHID1,SLC25A39,PARD3,SLC30A9,SMAP1,CDC40,PDAP1,TMX3,ARFIP2,ARF1,SLC12A9,GGA2,CSNK1A1,AP3S1,SCYL2,TFRC,CTSS,SLC1A4,SLC35B4,ABCD1,CAMK2G,RNF5,RBM15B,MLEC,RHOA,SNX2,PNPLA8,RHOT2,NEU1,RAB18,CACNB1,SEC23IP,KPNA4,PDCD6,ATP6V1D,GOLGA7,SNAP29,E2F1,PGRMC1,IMPDH1,USP20,PKD2,RBPJ,SPCS3,PGAM1,CHMP7,NUP188,PDCD6IP,ADAM10,TSC22D3,TMEM109,AP3M2,TAP1,GYG1,NHLRC3,SLC20A1,PARK7,RIC1,SLC25A37,PA2G4,SNUPN,ASAP2,CYB5RL,RAB4A,AP2B1,MARCH2,SLC26A2,TFG,SEH1L,SRSF10,SRP72,ORAI2,USO1,OSBP2,ATG9A,AKT2,ARHGAP45,DDX20,SLC17A5,MCFD2,SLC25A5,RAB2B,CLNS1A,IWS1,HHEX,WAS,TMED10,PSMD8,RPS14,EIF2D,ITGB1,SARAF,BTF3,RRS1,ARRB2,RTN3,ZMAT3,NMD3,SVIP,HSPH1,COX5B,DNAJC5,GMFG,VAV2,ANKH,ACAP1,B4GALT1,KIF23,NDUFA4,MAN2B1,SLC35B1,PSEN1,TMEM165,VPS25,COPG2,NDUFS7,NPLOC4,FKBP1A,SLC31A1,ARPC5,SNX18,LRRC8D,SLC25A51,ATP6V0A2,OSTF1,CYC1,PIKFYVE,LPCAT1,SYTL3,APOL1,TMED2,TERF2,EIF5A,FTL,GCC2,SIGMAR1,EMB,WDR1,C1orf35,RPS24,ADRB2,CAPZA2,ARID1A,PKM,CYFIP2,FXR1,PTTG1IP,TOMM40,GOSR1,CCT8,PSMB3,XRCC5,PI4K2A,DERL1,SEC31A,CAT,EPRS,SLCO4A1,GOLGA2,NSF,CSNK1G1,ERGIC3,ACLY,ARAP1,APPL2,PPP3R1,GPI,PPP6R3,CDK2,NRBP1,NDC1,SYS1,CKLF,TRIP10,RAB11B,RAF1,RAC1,GPR89A,SLC39A13,OLA1,BCL2L1,SLC25A44,AP1B1,CD320,MOAP1,APLP2,TNPO2,CDKN1B,BRI3,TAP2,TP53BP2,TMBIM1,CCT2,ATP13A1,VDAC2,CUL3,SLBP,LRRC8A,AP4E1,PSMB9,SERP1,ERC1,HSPA4,CHMP4A,DSN1,DDOST,RAB24,SEL1L,EYA2,DYNC1LI2,CSNK1D,SCAMP3,MECP2,MANBA,SLC41A1,SLC25A12,RAB11A,HEATR5B,PIP5K1C,WWP2,SLC25A36,JAKMIP1,EBP,RPL17,RPL19,SLC38A10,UPF2,TAGLN2,CNN2,CREB1,MTX2,IFT46,NCOA2,DENND1B,DENND4C,RPL8,RABIF,KCNQ1,RHOT1,KIF11,RPL27A,MACF1,SMAP2,YIF1A,HGS,RPL32,LTBP4,ATP5MC3,SLC38A7,CCZ1B,STX18,TFDP1,KHSRP,ASNA1,WDR91,GPR89B,IPO4,VPS29,ESYT2,POLA2,ADA2,MTX3,COPA,NF1,ALKBH5,UBE2Q1,ABCB10,KIF2C,SLC29A1,AGFG1,SNRPD3,BECN1,MAPK14,ATP5PF,CUTC,PCYOX1L,DST,RAP1A,CDC42,GOT2,EIF4A3,AP3S2,RAB35,ATG3,DPYSL2,SRI,KIF22,RP2,SLC35C2,CNNM3,CARMIL1,TIMM50,FYTTD1,LARS,NCK1,SLC16A7,SLC25A22,PITPNB,MPC1,RPL37,GEMIN5,HSPB11,EIF4ENIF1,UEVLD,TIMM29,MIA2,CAB39,CLU,VPS4A,ROCK1,RPS26,PSMC1,ATP6V0E1,CAPN1,STARD3NL,SLC12A7,TBC1D12,RPS15,TM9SF4,GORASP1,EPN1,RPL15,XPO7,RHBDD1,NUP205,CHKA,BANF1,CAPZA1,ORAI1,BCL2,KIFAP3,GLTP,SLC12A2,ATP6V0D1,CSNK1G3,KDELR1,ATP5IF1,CREG1,ERLIN1,RPL6,PSMA1,SYVN1,TMEM241,CAND1,TSC1,EXOC4,SLC16A1,NUP62,YWHAZ,CTSA,PITPNA,EHD4,TMEM14A,APOL2,WASF2,SNX27,CHMP2A,CORO7,TOMM20,CHERP,CLCC1,HNRNPA2B1,ANKRD28,ANKLE1,SAR1A,KIF14,AKAP8,PPP6C,PARL,SCAMP4,CYB5R1,APOOL,CLTB,CHTOP,PDIA6,F2R,ABI1,CHP1,NXT1,PSMB7,ATXN1,WIPF1,BICD2,ERBIN,TOLLIP,PEF1,RPS9,SURF4,VPS26C,ARNTL,CANT1,ANP32E,SCARB1,SMURF1,MAPK1,ABCA1,TMEM33,MIF,KIF3B,GOLPH3L,RAE1,SCYL1,DCTN2,SRGN,NUP54,VPS45,TIMM21,CHIC2,MFSD10,XPR1,FERMT3,KIF5B,GRK2,KLHL20,SEC24C,RRBP1,ZDHHC13,ANP32A,ARHGEF2,YIF1B,LDLRAD3,STAT3,SLC35A1,MICAL3,MYO5A,SLC25A1,NIPAL3,TGFB1,ZDHHC18,CSNK1G2,FAM49B,NASP,ATP2C1,SCFD2,COG1,WDR81,ATP5MF,SYMPK,MAPK3,HSPA1B,MFN2,UPF1,ELMO1,OSBPL8,COX8A,SRSF3,ATP6V1C1,HRAS,RAB3IL1 |
| 4.046e-13 | -28.54 | GSE2405_0H_VS_1.5H_A_PHAGOCYTOPHILUM_STIM_NEUTROPHIL_DN | MSigDB lists | GSE2405_0H_VS_1.5H_A_PHAGOCYTOPHILUM_STIM_NEUTROPHIL_DN | 190 | 69 | 17377 | 2626 |
KARS,PRKAB1,NUP188,SNX15,PMS2,OLA1,PTP4A3,SYNRG,ATPAF1,C2orf68,PRKD3,NOL11,EIF4A3,RAB35,DNM2,TAF5L,APOOL,MYBL1,ORAI2,EHMT1,RNPS1,FRAT2,MEF2D,AP4E1,CDCA4,RAD18,VPS26B,PSMD8,NRM,SH3GLB2,STK11,CCDC125,LTA4H,CWC25,OTUD5,UBE2D3,NADSYN1,ZCCHC9,CDC40,DNAJC5,PHF23,RAE1,CDT1,MRPS26,STRN4,KIF23,DNAJB1,PIP4K2A,FBRS,LYAR,ZBTB45,CTNNBL1,BTF3L4,RNF5,IMPA2,TACC1,FBXO9,ICAM2,CYFIP2,DDX23,RPA1,ELMO1,GPS2,PIAS2,E2F1,IMPDH1,PITPNA,TCOF1,DEF6 |
| 4.117e-13 | -28.52 | SRRM2 (serine/arginine repetitive matrix 2) | protein interactions | 23524 | 246 | 86 | 17029 | 2761 |
ADA2,SART1,CYLD,SARNP,SF3B1,RBM8A,CSNK2A1,SNRPD3,APP,SF3B2,PRNP,HNRNPA2B1,EIF4A3,PIN1,SRSF4,CDK12,SRPK2,PRPF19,CDC5L,BAK1,SNRNP200,SEPT9,MRPL12,CUL3,HNRNPF,RNPS1,PRPF3,DNAJA1,NDUFA7,LUC7L,MBD3,DHX15,EIF3H,SRSF1,RAD18,CLK3,DHX16,BAZ1B,ARRB2,NKAPD1,PSMC1,HDAC2,PRPF4B,UNK,RPS2,DHPS,DHX9,CDC73,PIP4K2A,LMNA,SUB1,DNAJC8,EFTUD2,YBX1,FBL,HNRNPM,EEF1D,LUC7L2,TERF2,SRSF11,GTF3C6,ZMYND11,MTA2,USP42,ILF3,RPL6,SEPT8,RTF1,SRSF5,PLEC,SEPT7,SF3A2,PSMC4,CAND1,TRIM26,SYNCRIP,RBM25,RBMX,HNRNPH3,DDX5,WDR76,RUVBL2,RBBP4,SNRNP70,CDK2,YWHAH |
| 4.121e-13 | -28.52 | GO_REGULATION_OF_CELLULAR_PROTEIN_CATABOLIC_PROCESS | MSigDB lists | GO_REGULATION_OF_CELLULAR_PROTEIN_CATABOLIC_PROCESS | 262 | 86 | 17377 | 2626 |
ZNF207,SUMO2,CUL1,CSNK2A1,SIRT2,UBQLN2,CCNB1,PRKACA,ANKIB1,PARK7,BCAP31,FBXO22,USP5,RAD23A,MDM2,PSMD1,PSMA6,UCHL5,RAD23B,ANAPC7,RNF19A,SENP1,PDCL3,PLK3,PLK1,UBQLN4,PSMA8,PBK,PSMB7,CUL3,EZR,CDC23,RAB1A,PSMB9,CDC16,RPS27A,PSMD8,NSMCE2,AXIN1,PSMD3,SOCS4,XRCC3,CLU,DVL1,GEN1,SMURF1,PSMC1,CSNK1D,SVIP,GORASP1,DNAJB2,CENPF,UBXN1,NKD2,CSNK1A1,PSMD9,PSEN1,MAD2L2,FBXO5,DDRGK1,RB1,PSMD2,PTEN,SOCS5,TNFAIP3,GBA,PSMA1,ANAPC2,PTTG1IP,PSMB3,PSMC4,GNA12,HSPBP1,KEAP1,CDC27,GOLGA2,PML,RNF14,UBE2C,CD81,ESPL1,TERF1,RNF139,CDKN2A,ANAPC4,RNF114 |
| 4.144e-13 | -28.51 | GSE3982_NKCELL_VS_TH2_DN | MSigDB lists | GSE3982_NKCELL_VS_TH2_DN | 186 | 68 | 17377 | 2626 |
TMEM106C,POLA2,H2AFZ,ST13,PTTG1,LAGE3,GLUD1,KIF2C,POMP,SNRPD3,C2orf49,FANCI,MDM2,PCNA,CCNA2,RALB,GMEB1,RPP25,TDP1,SEC61B,CDC123,VDAC2,E2F3,EZR,RRM2,NUSAP1,SMC2,CLNS1A,GINS4,SRSF1,PPP2CA,DAP3,KIF18B,XRCC3,SNRPG,NMD3,HIVEP3,C1orf112,RRM1,NCAPG,PNO1,DTL,TNS3,CLIC4,MCM5,MSH2,H2AFY,LUC7L2,LDHB,FDFT1,HEMK1,NASP,KIF11,GUF1,SYMPK,UTP20,SLCO4A1,KIF18A,ATAD2,PRDX3,BIRC5,TFDP1,PRPS2,SIAH2,EHD4,CCNB2,MRPL3,ESPL1 |
| 4.163e-13 | -28.51 | GO_PEPTIDYL_LYSINE_MODIFICATION | MSigDB lists | GO_PEPTIDYL_LYSINE_MODIFICATION | 284 | 91 | 17377 | 2626 |
ASH1L,NUP188,CXXC1,SUMO2,SIRT2,TAF6L,UBE2I,MEAF6,PHC2,SAP130,TET3,MDM2,PCNA,NUP210,SP100,BRPF3,MTA1,NUP107,NUP153,TAF5L,FAM76B,ATF2,SENP1,ARID4A,SEH1L,SP3,KAT7,EHMT1,ELP4,WDR82,KIAA1586,TOPORS,NUP155,AURKB,BRCA1,USP22,MBD3,TRIM28,DOT1L,NSMCE2,CAMKMT,OGT,NCOA1,BEND3,XRCC4,NAA60,CBX4,AAAS,NSMCE4A,DHPS,EYA1,MECP2,RAE1,CDCA8,FAM76A,NUP54,SMC6,TOP2B,JMJD6,EZH1,BLM,WDR5,SUPT7L,NUP205,IRF4,SMC3,SUV39H2,HDAC7,ZNF335,NAA50,CTR9,NUP85,NCOA2,EIF5A,KAT2A,LDB1,RANGAP1,RTF1,NFATC2IP,MEN1,KDM3A,RPA1,MBIP,BIRC5,SETD3,PIAS2,PML,NUP62,TAF12,RUVBL2,CDKN2A |
| 4.195e-13 | -28.50 | Membrane Trafficking | REACTOME pathways | R-HSA-199991 | 610 | 169 | 10287 | 1696 |
RAB14,TMED7,COPA,TSC2,TGOLN2,AGFG1,KIF2C,UBQLN2,SEC16A,MAP1LC3B,RIC1,KIFC1,CALM2,NAPG,RAB8A,RAB35,RAB4A,AP1M1,DNM2,AP2B1,KIF22,TFG,COPS8,TRAPPC13,USO1,RHOBTB3,TMEM115,AKT2,KIF15,MCFD2,STX16,RAB5B,ARF4,OPTN,NECAP2,MAN2A2,TBC1D17,KIF18B,TMED10,RPS27A,MIA2,VPS4A,COPS6,ARRB2,C2CD5,SCOC,GORASP1,GGA1,CCZ1,EPN1,KLC1,KIF23,RACGAP1,TMED3,RAB6A,VPS25,COPG2,COPB2,GNS,CD59,ARPC5,SNX18,RINL,KIF13B,KIFAP3,PPP6R1,TMED2,KDELR1,PREB,FTL,GCC2,CYTH1,TRAPPC9,ADRB2,ARPC1A,GOSR1,SEC31A,SCARB2,TSC1,GOLGA4,GALNT2,GOLGA2,NSF,SNAP23,EXOC4,YWHAZ,PPP6R3,ALS2,EXOC3,PRKAB1,ANKRD27,CHMP2A,SYS1,REPS2,TRIP10,RAB11B,DYNLL1,COPE,RAC1,ANK3,ACTR3,VTI1A,MON1B,TBC1D13,AP1B1,APP,REPS1,STAM,ANKRD28,RAB21,TBC1D14,PPP6C,CLTB,LMAN1,NAA35,GCC1,DVL2,DCTN1,RAB7A,BICD2,CHMP2B,RAB1A,AP4E1,KIF2A,CHMP4A,SURF4,AP1S1,CHMP4B,AP2S1,CSNK1D,DYNC1LI2,KIF3B,GOLIM4,DCTN2,VPS45,ARFIP2,AGPAT3,ARF1,GGA2,AP3S1,RAB11A,TFRC,PIP5K1C,MAN1A1,KIF5B,GRK2,SEC24C,ARF5,COPS7B,MYO5A,SPTAN1,SNX2,DENND1B,DENND4C,COG1,RAB3IP,KIF11,PICALM,RAB18,HGS,KIF18A,SEC23IP,SNAP29,CCZ1B,STX18,CHMP7,YWHAH,RAB3IL1,SNAPIN |
| 4.211e-13 | -28.50 | GOLT1B (golgi transport 1B) | protein interactions | 51026 | 175 | 68 | 17029 | 2761 |
NDUFA5,IMMT,PDCD6IP,RAB11B,TMEM109,ATP6V1B2,ATP5PF,KTN1,BCAP31,RAB8A,ATP2A2,CDC42,NABP1,ATP6V1G1,VDAC2,TMEM216,ATP6V0A1,NDUFA7,NDUFB1,VDAC1,CHMP2B,STOML2,MAP3K4,CHCHD3,ATP1A1,PLGRKT,COX5A,SARAF,CHMP4B,PIEZO1,REEP4,CHPF2,RECQL,NDUFV2,NDUFS1,TMUB1,GOLIM4,PHB2,FLOT1,COX4I1,ATP5F1B,FAM8A1,REEP5,XPR1,LMNA,TFRC,NDUFS4,CD59,NDUFV1,NDUFA2,INTS7,NDUFB4,NDUFS8,CYC1,ALDH18A1,ATP6V0D1,MLEC,ERLIN1,ATP2C1,VKORC1,CHCHD6,HGS,PDCD6,ATP6V1D,GOLGA2,OSBPL8,ATP5F1A,NDUFS5 |
| 4.354e-13 | -28.46 | DDX5 (DEAD-box helicase 5) | protein interactions | 1655 | 226 | 81 | 17029 | 2761 |
SART1,CYLD,SUZ12,CUL1,SMARCA4,UBE2I,RBM4,PABPC4,MDM2,SHC1,EIF4A3,PIN1,AKAP8,TARDBP,TCEA1,CDC37,PRPF19,RYBP,CDC5L,VHL,HNRNPF,CUL3,AURKB,BRCA1,MCM2,PRPSAP1,MBD3,DHX15,SRSF1,DDX17,HNRNPR,DGCR8,CHD3,WDR4,ATXN2L,FUS,COPS6,ARRB2,SMURF1,XRCC4,HDAC2,RMND5A,UNK,DNAJC2,GOLIM4,TRMT6,NACA,DHX9,THRAP3,LMNA,WWP2,RPA2,MCM5,DAPK1,RPL19,FBL,LRSAM1,HNRNPM,LUC7L2,STAU1,PRKDC,ERO1A,GTPBP4,EIF2A,ARMC8,SF3A2,MATR3,POLR2A,RPA1,CAND1,DERL1,EPRS,UPF1,SYNCRIP,RBMX,HNRNPH3,IMPDH1,DDX5,YY1,CDK2,CD81 |
| 4.441e-13 | -28.44 | GNF2_CENPE | MSigDB lists | GNF2_CENPE | 39 | 26 | 17377 | 2626 |
RFC3,FOXM1,ASPM,CENPF,CDCA3,MKI67,MYBL2,RRM1,CDCA8,RRM2,NUSAP1,AURKB,SMC2,CCNF,SHCBP1,KIF11,PRIM1,PCNA,CCNA2,KIF18B,BIRC5,H2AFX,PRC1,CCNB2,UBE2C,ESPL1 |
| 4.719e-13 | -28.38 | cell cycle phase transition | biological process | GO:0044770 | 270 | 88 | 17256 | 2622 |
POLA2,FGFR1OP,CHMP2A,MAX,GPR132,FOXM1,DYNLL1,ENSA,CUL1,ORC1,CCNB1,PRKACA,CDKN2C,RAB8A,CCNA2,PCNA,PPME1,AKAP8,PPP6C,DNM2,CDKN1B,CDC25B,CEP63,TACC3,DCTN1,PLK1,PLK3,BRD4,CUL3,SLBP,RRM2,CDC6,PKMYT1,CDC23,MCM2,OPTN,PRIM1,TAF2,RPS27A,E2F4,ITGB1,CHMP4B,CHEK2,TFDP2,PPP2R2D,CSNK1D,TUBB,CTDP1,MAPRE1,MCM10,PPP1R12A,CDT1,DCTN2,DBF4,HAUS4,CRLF3,HAUS2,FBXO5,RPA2,RB1,CCP110,CENPJ,MCM5,TIMELESS,FBXL7,ORC3,CAMK2G,PPP3CA,PRIM2,NASP,BORA,RPA1,MASTL,HAUS8,PCM1,UPF1,POLE,CDC27,TFDP1,ODF2,E2F1,SSNA1,NDE1,CCNB2,UBE2C,CHMP7,CDK2,CDKN2A |
| 4.917e-13 | -28.34 | GO_REGULATION_OF_ORGANELLE_ORGANIZATION | MSigDB lists | GO_REGULATION_OF_ORGANELLE_ORGANIZATION | 1109 | 255 | 17377 | 2626 |
ZBED3,SKA3,PDCD6IP,ADD1,KDM4A,ZDHHC8,XIAP,CSNK2A1,SIRT2,UBQLN2,CCNB1,BECN1,MAP1LC3B,BIRC2,PARK7,KIFC1,ABL2,CDK5,NEK6,CDC42,ATG3,RABGAP1L,SIVA1,NOC2L,DNM2,DNMT1,MTPN,MLST8,BAK1,PLK1,ERCC1,SEPT9,NCK1,AKT2,TLK1,GMFB,EZR,LRP5,ARHGDIB,CDC6,AURKB,BRCA1,CCNF,ANLN,SLC25A5,STOML2,IWS1,PAF1,MAP3K4,TBC1D17,WAS,MID1IP1,CHD3,PSMD8,LIMK1,MAP4,ATXN2L,OGT,ROCK1,VPS4A,CHEK2,ARRB2,POT1,UBE2D3,TBC1D12,MAPRE1,GMFG,PHF23,GORASP1,PHB2,CENPF,CIB1,KCTD17,KIF23,CTCF,RACGAP1,HAUS4,CDK13,NCKAP1,RGS2,HAUS2,APOPT1,JMY,LMNA,SPAG5,RB1,PDXP,VASP,SMC3,ARPC5,CAPZA1,ZNF335,MSH2,CTR9,BCL2,KNTC1,PIKFYVE,LRSAM1,NSUN4,TERF2,CYFIP1,WDR1,PIP4K2C,MYBL2,RTF1,ADRB2,CAPZA2,SEPT7,KDM3A,ARPC1A,MAP2K2,CCT8,DAPK3,XRCC5,HAUS8,TSC1,CDC27,GOLGA2,ODF2,CDCA5,PPP3R1,ARAP1,CNOT6,YWHAZ,RUVBL2,CDKN2A,WASF2,ZNF207,USP7,ANKRD27,CHMP2A,CYLD,FEZ2,DYNLL1,RAC1,ACTR3,PTTG1,TPX2,STARD7,PLAGL2,MYH9,TBC1D13,BCL2L1,TWF2,STMN1,STAM,TERF2IP,MOAP1,TBC1D22A,RALB,TBC1D14,PIN1,AKAP8,PARL,CDKN1B,CORO1A,MAVS,CEP63,TP53BP2,CYB5R1,CHTOP,LMAN1,HTRA2,PPIF,CCT2,UBQLN4,PSRC1,BIRC3,EID1,RAB7A,TAOK1,PSMB7,CUL3,TUBGCP5,WBP2,WIPF1,NUSAP1,PKMYT1,CDC23,RAB1A,VDAC1,CHMP2B,TRIM28,USP36,KIF2A,CDC16,CHMP4A,SURF4,NSMCE2,UHRF2,XRCC3,CHMP4B,GEN1,MAPK1,SMAD4,CSNK1D,TUBB,TMEM33,KIF3B,TRIP12,MECP2,DCTN2,ARFIP2,ARF1,RAB11A,TUBGCP2,PIP4K2A,MAD2L2,FBXO5,CAPN2,STARD9,CLIC4,PTEN,HUWE1,CENPJ,PRC1,AXIN2,BRD7,H2AFY,ARHGEF2,ATG13,CNOT6L,RNF5,MYO5A,SPTAN1,TGFB1,PPP1R9B,RHOA,KAT2A,ASPM,NEK7,MIER1,BORA,KIF11,MARK2,SH3GLB1,MAPK3,MTMR3,INF2,KIF18A,ATAD2,BIRC5,STX18,TFDP1,LRPPRC,PML,E2F1,WDR62,UBE2C,YWHAH,PARP10,ESPL1,TERF1,HRAS,ANAPC4 |
| 5.517e-13 | -28.23 | MODULE_8 | MSigDB lists | MODULE_8 | 409 | 118 | 17377 | 2626 |
TMEM106C,IMMT,FOXM1,SUZ12,TOR1AIP1,PTTG1,TMEM97,UCK2,TPX2,SMARCA4,SLC29A1,GYG1,SNRPD3,CCNB1,STMN1,BIRC2,PAIP1,MBD4,SSR1,SEC11A,DECR1,PCNA,CCNA2,TNFAIP8,GRSF1,ATP13A3,DNM2,NUP153,DNMT1,PTPRK,SP3,PLK1,SGCE,KLF10,DPM1,CDC123,LYRM1,TLK1,MAP4K4,PSMB7,MRPL12,GMFB,E2F3,SLBP,HTATIP2,AURKB,NUTF2,SOX4,MCM2,PRPSAP1,CHAF1A,DDX17,PON2,DAP3,IARS2,ADAM9,CLN3,DDX42,SLC30A9,MAPRE1,POLR2K,CENPF,UBXN1,DHX9,RRM1,ARFIP2,CTCF,SLC4A2,TMED3,RGS2,ITGB5,RAB11A,WRB,MYL6B,HDDC2,TFRC,NUP205,EBP,CHKA,TFAP4,FGFR3,PDCD10,SEC24C,MSH2,AHCY,MRPL40,UBE2M,TMX1,MSH6,SLC25A1,STAU1,TK1,PRKDC,ACSL3,ILF3,ADSL,ARPC1A,DDX39A,ABCF1,FADD,CYB5A,PSMC4,RPA1,CBX3,SDHB,ATP6V1D,TFDP1,MAPK6,DCAF11,LRPPRC,CEBPG,RBBP4,CDK2,UBE2C,CCNB2,MRPL3,BYSL,CDKN2A |
| 5.563e-13 | -28.22 | GSE3982_NKCELL_VS_TH1_DN | MSigDB lists | GSE3982_NKCELL_VS_TH1_DN | 187 | 68 | 17377 | 2626 |
TMEM106C,H2AFZ,ST13,NQO1,PTTG1,TPX2,ZFYVE21,KIF2C,SNRPD3,POLR3K,BCAT2,RAD23B,PTPRK,RPP25,CDC123,IDH3A,RRM2,GLO1,NUP155,SMC2,USP22,GINS4,CLNS1A,PRIM1,RBM47,NIP7,H2AFX,KPNA2,PDXK,MRPL13,USP13,HIVEP3,GCLM,DEPDC1,CASP6,RRM1,PXMP2,BLM,NCAPG,RAB11A,CD59,KIF5B,TNS3,ERH,SNRNP25,IRF4,MCM5,PELO,MSH2,ANXA5,PPA1,MYO5A,HNRNPM,CYFIP1,NASP,KIF11,SYMPK,SLCO4A1,TWSG1,BIRC5,ACOX1,FAM3C,TFDP1,YWHAH,CCNB2,UBE2C,ESPL1,CDKN2A |
| 5.669e-13 | -28.20 | HNRNPR (heterogeneous nuclear ribonucleoprotein R) | protein interactions | 10236 | 211 | 77 | 17029 | 2761 |
SART1,IMMT,CYLD,IVNS1ABP,SF3B1,MOGS,CUL1,SND1,SNRPD3,FARSA,STRBP,EIF4A3,TARDBP,CDC5L,SNRNP200,VHL,HNRNPF,CUL3,WDHD1,LSM8,BRCA1,MCM2,LUC7L,TRIM28,DHX15,SRSF1,DGCR8,EIF2D,MAP4,H2AFX,MPV17,ARRB2,MAPK1,CAPN1,RPS2,MRPL42,TCF3,TRMT6,MRPS26,DHX9,TOP2B,NPLOC4,LMNA,TMEM179B,RPA2,NDUFV1,MCM5,PPP4R1,EFTUD2,ZNF746,MRPL40,FBL,PABPC1,MTX2,HNRNPM,LUC7L2,SPTAN1,STAU1,MTA2,ILF3,SRSF5,RHOT2,SF3A2,MATR3,POLR2A,ZFR,RPA1,DDX23,CAND1,UPF1,SYNCRIP,CCDC6,RBMX,HNRNPH3,DDX5,SNRNP70,HNRNPDL |
| 5.906e-13 | -28.16 | regulation of gene expression | biological process | GO:0010468 | 4804 | 883 | 17256 | 2622 |
ZBTB10,KDM4A,HEXB,XIAP,CCNL2,EDRF1,RBM4,ZNF275,PABPC4,RPL23A,CDK5,USF1,PSMD1,CIPC,NSRP1,THAP4,SRSF4,DNM2,CRY2,NUP153,FNIP2,ECD,ZNRD1,TIPARP,SENP1,BAK1,PLK3,ZNF672,ZNF559,AATF,GABPA,EHMT1,HNRNPF,WDHD1,MIER2,TOPORS,SLC50A1,ARF4,BRMS1,BOLA3,AHNAK,SMAD2,RPS27A,ZNF689,AXIN1,PRDX5,OGT,VIPAS39,RNASEL,TRIM52,SMG9,TFDP2,SMAD1,E2F2,ZNF75A,AAAS,PDCD4,ZNF720,SSRP1,HIVEP3,DHX9,EZH1,EIF2AK4,PSMD9,PARN,CDC73,LMNA,MCTS1,DDRGK1,CD59,TFAP4,MEGF8,PHF14,ZNF326,FOXN2,MYDGF,CPSF4,PABPC1,NUP85,NSUN4,CYFIP1,IFRD1,AGGF1,RBM42,ETV3,FOXK1,RB1CC1,ZMYND11,MTA2,RPS10,MYBL2,BCLAF1,SRSF5,CBFA2T2,ELK1,EIF4H,MATR3,POLR2J,PDLIM1,ETS2,SETD3,CNOT6,SGF29,RNF139,NUP58,EGLN1,ZNF207,RHOG,ZNF296,KARS,SARNP,GGNBP2,TRERF1,IVNS1ABP,UBR2,PTTG1,ANK3,WDTC1,MYH9,CREBL2,ZNF267,INO80E,SAFB2,PRKACA,RCOR3,TCF19,APP,AHCTF1,ZNF420,SP100,ZKSCAN1,MTA1,GMEB1,NUP107,ZNF226,MAVS,ATF2,RBM15,ZC3H3,RPRD1B,CGGBP1,CPNE1,PSRC1,POLR2L,EID1,KAT7,WBP2,RPL38,POLR2D,RNPS1,CIRBP,E2F3,HTATIP2,MEF2D,DDX17,TAF2,PPP2CA,CHCHD3,LSM6,HIPK2,NT5C3B,RPLP1,TICAM1,FUS,ZBTB11,LRP8,USP13,COMMD10,ZNF786,RPS2,ZNF445,SRSF6,ZFP91,HABP4,TRAK1,JMJD6,GMCL1,ABHD14B,WDR5,ETS1,NEXMIF,ZNF92,TUT4,ZBTB45,PSMD2,PDCD10,ITGB8,SUV39H2,PPP1R8,PRDM4,ZNF260,DCP1A,LTN1,ZNF710,GTF2H2,MED22,PDPK1,PPP3CA,TNFAIP3,ZNF512,ZP3,DDX39A,PICALM,ZNF862,ZNF180,KEAP1,GPS2,PITX1,MAPK6,LRPPRC,PML,HMGB2,CD81,PARP10,IGBP1,USF2,YWHAH,THAP5,FAF1,AGRN,THOC1,AAMDC,GPBP1L1,TRIM11,PPP1R15B,FAM129A,RBM8A,CSNK2A1,SND1,BIRC2,PAPOLA,CREM,PRNP,LIN9,TET3,PCNA,NUP210,GLIS2,ZNF639,ETV6,PIK3R2,NOC2L,EIF5,MYBL1,MTPN,CCAR1,RYBP,CDC37,PTPRK,PLK1,SP3,EXOSC6,CELSR2,RBX1,PBXIP1,BAZ2A,ZBED5,MRPL12,EZR,CDC6,UBE2V1,LRP5,PBRM1,EAF2,BRCA1,PRKRA,USP21,TONSL,CHD3,ZNF367,E2F4,ACTB,DVL1,ZNF45,BEND6,FAM208A,ZNF564,FUBP1,LZTR1,PHB2,CENPF,NKD2,CTCF,CHCHD2,CDK13,DNAJB1,PPP3CB,RLF,ASXL2,CNOT11,CRLF3,ARID1B,LRRC14,SUB1,RB1,MLX,MED8,MBD2,SSBP3,ZNF746,CTR9,TIMELESS,MDFIC,RBM3,AFF1,ICE2,GLE1,MAML1,PREB,TRAPPC9,LDB1,UTP15,KRAS,EIF2AK1,RTF1,ZNF761,NFATC2IP,EIF4G2,RBM38,IRF5,ZNF174,PSMC4,RXRB,RPL36,SYNCRIP,NLRC5,TBPL1,PRMT7,RUVBL2,USP7,CYLD,TRAF7,RPLP2,ARID2,FOXM1,DYNLL1,ZNF416,DUSP22,PCBP1,COMMD8,ZNF121,RPL11,VAV1,CSDE1,ZBTB21,NRF1,PSMA6,ZNF473,MDM2,KMT5C,ZNF302,PIN1,TARDBP,AHCYL1,STRAP,SAP30L,ZNF583,DVL2,PRPF19,KDM3B,RPL29,RPL35,BIRC3,POLR2G,ZNF780B,PSMA8,BTG2,PPIE,NUP155,NFATC2,KDM1B,EIF3H,RPSA,USP36,SRSF1,SCAP,ZNF700,RBL1,CLK3,MAFK,FASTK,PSMD3,TIMM17A,PLGRKT,ZNF436,UHRF2,DNAJC17,NCOA1,H3F3A,SMAD4,ZNF146,BCL2L12,SLC30A9,CTDP1,UNK,MIF4GD,MTERF1,DAP,CDT1,AGO2,ARID5A,GTF3A,HMGN3,NKRF,CDK11B,PAGR1,FZD6,PTPN2,IRF4,SS18L1,POLR1B,RBM15B,YTHDC1,RPRD1A,RHOA,HMGN5,BTAF1,PRKDC,ZNF202,ZMYM5,PCGF1,TRIM26,BIRC5,TWSG1,L3MBTL3,TFE3,CDCA7L,BBX,E2F1,GLG1,PKD2,RBPJ,TAF12,NR2F2,HIPK3,IFI16,NUP188,TXN,ZNF496,MAX,H2AFZ,TSC22D3,CXXC1,YTHDF3,CCNB1,UBE2I,EIF1B,COMMD6,MYEF2,PARK7,GLMP,PA2G4,NOL11,FIZ1,ZNF200,TRA2B,TAF5L,SMARCE1,DNMT1,ZNF800,SEH1L,CDC5L,SRSF10,ZNF524,KLF10,AKT2,ELOA,DDX20,AURKB,USP22,CBFB,ZMYM3,IWS1,DOT1L,MAP3K4,HHEX,MKNK1,BRD2,PSMD8,RPS14,BTF3,ARRB2,TRAF5,ZNF598,CCDC59,HDAC2,PTOV1,DDX58,HSPH1,EWSR1,POLR2K,PRKAA1,GSPT2,PMF1,NOTCH2,SUPT7L,ZNF79,PSEN1,ZNF518A,METTL3,VPS25,YY1AP1,CNOT3,JMY,CFLAR,LHX8,EXOSC7,MEX3C,KLF16,HDAC7,DAPK1,TNRC18,EEF1D,TMED2,TERF2,EIF5A,PHF10,ZNF84,ELL2,ZNF574,USF3,RPS24,EXOSC9,ARID1A,ADRB2,C9orf40,CYFIP2,FXR1,KDM3A,PATL1,MAP2K2,PSMB3,TWISTNB,PHF6,XRCC5,CAT,PFDN5,EPRS,ZNF777,SERTAD2,EPOP,ZFP92,RBMX,QARS,MED15,CEBPG,PPP3R1,PIAS2,TCOF1,YY1,MAP3K5,RNF14,CDK2,ZC3HAV1,CDKN2A,ZNF511,NDC1,DNMT3A,ATXN3,RWDD1,ZBTB37,RPS6KA1,SF3B1,RAF1,SUZ12,CAST,EIF3D,MAGED1,PAIP2,TERF2IP,SPINDOC,CCNA2,ZNF75D,SHC1,KDM2A,UCHL5,LPIN2,MRPS27,CDKN1B,CDK12,SAP30,BRD4,ERF,CDC123,DRAP1,CUL3,ELP4,EDF1,PSMB9,H2AFV,ERC1,TRIM28,SERP1,CENPU,PRDM11,SUPT16H,EIF3K,VEZF1,ZNF282,HINT1,DGCR8,CERS6,SAFB,H2AFX,STAT1,ATF6,TRIM32,BEND3,EYA2,CSNK1D,ATMIN,RHEBL1,POU3F2,NCOR2,DEPDC1,MECP2,TCF3,ARGLU1,SECISBP2,MYNN,BLM,POFUT1,FOXO3,HMG20A,MAD2L2,WWP2,GTF2F1,RBM17,CCNK,RPL17,PTEN,ELP5,FUT8,AXIN2,RPL19,UPF2,CARF,CITED2,CNOT6L,CREB1,NCOA2,TSHZ1,ZFP64,KAT2A,ILF3,RPL8,RFXANK,TBRG4,KCNQ1,RPL27A,KLF6,COMMD4,FADD,POLR2A,CBX3,HGS,RPL32,PRDX3,ZHX1,TFDP1,KHSRP,DDX5,BRWD3,TAF6,CPEB2,PURA,FAM83G,RORB,ZBED3,CCNC,ZNF76,IER2,NOP2,HNRNPAB,UBN1,NF1,KMT2E,DNAJC24,ZNF107,PTP4A3,TAF6L,SIRT2,COMMD5,MAPK14,SNAPC4,ZNF696,EDC3,ZNF804A,EIF4A3,METTL14,JAZF1,PHTF1,SRI,ZBTB22,TCEA1,SLC35C2,OGG1,ARID4A,TRIM14,CARM1,ELOF1,SRPK2,DEAF1,TRIM8,NCK1,VHL,RIOX2,SREK1,RRM2,SOX4,KMT2C,ASF1B,RPL37,PAF1,GEMIN5,UBTF,EIF4ENIF1,BRWD1,PQBP1,BAZ1B,ZNF268,CHEK2,CLU,ROCK1,RPS26,PSMC1,UBE2D3,RPS15,PPP1R12A,ZNF768,NACA,CIB1,MED13L,TIA1,RPL15,MEF2A,THRAP3,RGS2,EPHX2,TTF1,SRRT,RHBDD1,PRPF18,NUP205,LYAR,NFATC3,ZNF449,MED10,BUD31,ZNF335,BCL2,YBX1,ACAD8,MCPH1,ZNF189,HP1BP3,VOPP1,POLR2I,CREG1,ERLIN1,CIC,RPL6,PSMA1,EIF2A,SLTM,DAPK3,CAND1,TSC1,RBM25,NFIL3,NUP62,YWHAZ,ZFP90,RBBP4,SNRNP70,HNRNPDL,TOB1,N4BP2L2,ZBTB24,SMARCD1,ADNP2,TCF12,MBD1,PRKAB1,ASH1L,MPHOSPH8,SMARCA4,PLAGL2,NSD3,IRF3,ORC1,CHD1,MEAF6,MXD1,PAIP1,HNRNPA2B1,SAP130,RRN3,UBXN2A,CD3EAP,EXOSC1,AKAP8,CHTOP,F2R,UTP4,ZNF770,RLIM,MOSPD1,CHP1,POU2AF1,FAM172A,ZNF500,RNF25,SMU1,PCGF6,PSMB7,ATXN1,BOLA1,GLO1,ERBIN,MBD3,RPS9,ZNF317,TAB2,HNRNPR,TULP3,STAT6,ARNTL,AKNA,SMURF1,MAPK1,BRD9,CBX4,NAT14,MIF,DNAJC2,ZNF316,EYA1,RAE1,SCYL1,NUP54,KLF13,PAWR,MXD4,FBXO5,FASTKD3,KMT5A,PELO,H2AFY,BRD7,ANP32A,ARHGEF2,LDLRAD3,STAT3,TGFB1,SAMD4B,PHF20L1,COA3,DCAF6,HMGN1,PSPC1,MIER1,RCOR1,PRMT2,MEN1,ZNF407,CDK11A,SNRPA,MAPK3,TFEB,HSPA1B,CNOT9,LEMD2,UPF1,ATAD2,ZC3H7B,KMT2B,ZRANB2,SRSF3,CENPT,ZMIZ1,HRAS,TERF1 |
| 6.830e-13 | -28.01 | sister chromatid segregation | biological process | GO:0000819 | 195 | 70 | 17256 | 2622 |
ZNF207,CHMP2A,PDCD6IP,DYNLL1,NUF2,KIF2C,CCNB1,BECN1,MIS12,KIFC1,AHCTF1,KIF14,AKAP8,NUP107,PDS5B,KIF22,MCMBP,SEH1L,PLK1,PSRC1,TAOK1,CUL3,NUSAP1,SMC2,AURKB,CHMP2B,CDC23,CENPU,KIF2A,RAD51C,CHMP4A,DSN1,KIF18B,CEP55,CHMP4B,VPS4A,RRS1,DYNC1LI2,MAPRE1,PHB2,PHF23,CDT1,CENPF,CDCA8,KIF23,RACGAP1,TOP2B,PMF1,SPDL1,NCAPG,RAB11A,SPAG5,RB1,SMC3,NAA50,PRC1,KNTC1,CENPM,NUP85,SMC4,NUDC,RANGAP1,KIF18A,BIRC5,CDCA5,NUP62,CENPT,NDE1,CHMP7,ESPL1 |
| 6.833e-13 | -28.01 | GNF2_FBL | MSigDB lists | GNF2_FBL | 140 | 56 | 17377 | 2626 |
RPS15,KARS,RPS2,MRPL9,ST13,SUZ12,EIF3D,NACA,RPL15,GTF3A,SNRPD3,UBE2I,RPL23A,HNRNPA2B1,NUP210,NOL11,RPL17,TRA2B,RPL19,TARDBP,FBL,RBM15,SRSF10,RPL29,EIF3L,HMGN1,RPL35,SNRNP200,RPL8,RPS10,HNRNPF,RPL38,RPL6,MRPL16,UTP3,DDX39A,DHX15,RPSA,EIF3H,SRSF1,RPL36,NSA2,RPL37,DAP3,NAP1L1,HSPB11,SYNCRIP,HINT1,RPL32,HNRNPR,QARS,RBMX,U2SURP,SRSF3,BTF3,CCDC59 |
| 7.215e-13 | -27.96 | GSE22886_NAIVE_CD4_TCELL_VS_12H_ACT_TH2_DN | MSigDB lists | GSE22886_NAIVE_CD4_TCELL_VS_12H_ACT_TH2_DN | 192 | 69 | 17377 | 2626 |
ZNF207,IMMT,TAP1,STARD7,CSNK2A1,ZNF267,POMP,SLC25A44,PARK7,FANCI,RAB21,NAPG,RBM23,PCNA,MTMR4,PPCDC,TARDBP,AQR,TFG,MINPP1,AHCYL1,PTPRK,ERCC1,SEC61B,HSPB11,HINT1,CANT1,TRIM32,PFKP,MIF,GCLM,GALK1,MRPL42,TRIP12,MUT,SCAMP3,CDT1,RAB23,RRM1,ARID5A,RACGAP1,MYL6B,WRB,REEP5,COPB2,TFRC,MED8,AHSA1,TANK,CLDND1,TMED2,CYFIP1,TIMM8B,NEK7,ACSL3,WDR18,JTB,SEPT8,PSMA1,MRPL16,TARS,YIF1A,PDCD6,PRDX3,FAM3C,COX8A,SLC16A1,CDK2,ZBTB24 |
| 7.431e-13 | -27.93 | BLALOCK_ALZHEIMERS_DISEASE_UP | MSigDB lists | BLALOCK_ALZHEIMERS_DISEASE_UP | 1616 | 346 | 17377 | 2626 |
ZBTB10,MAX,PNISR,CXXC1,ABCC10,TAP1,CMTM6,CDKN2C,CDC25B,MAST2,SLC26A2,MOB1A,TIPARP,CDC5L,RHOBTB3,MCL1,TOPORS,USP22,CBFB,RAB22A,WAS,SMAD2,BRD2,LUC7L3,MAP4,SMAD1,CCDC59,PDCD4,B4GALT2,DDX42,EWSR1,GGA1,HLA-E,CCZ1,GADD45G,MAN2B1,ITGB5,LMNA,CFLAR,HDAC7,TNPO3,FBXL7,PABPC1,LUC7L2,EEF1D,FDFT1,PHF10,FTL,IFRD1,ZNF84,TSPAN31,MAN1B1,RPS10,USP10,SSR2,ARID1A,PLEC,PTTG1IP,FXR1,ELK1,GOSR1,KDM3A,MAP2K2,SF3A2,AKAP1,PI4K2A,PTPRF,EPRS,SERTAD2,OSBPL11,KPNA1,CSK,QARS,ARAP1,TCOF1,WIPI2,YY1,PPP6R3,NDE1,CDK2,ZC3HAV1,NQO1,RAB11B,TRIP10,CAST,RPS6KA1,UROD,RAC1,AP1B1,DAZAP2,CPNE3,APP,KTN1,PHC2,CRKL,CYHR1,AHCTF1,SHC1,SP100,KDM2A,MTA1,DUT,RNASEH2A,RNF19A,RBM15,CDK12,ILKAP,GCC1,TMBIM1,CGGBP1,SAP30,ADCY7,BRD4,ERF,RPL38,PFKFB3,HTATIP2,EDF1,TAZ,H2AFV,MAT2A,VEZF1,CDC16,SAFB,HIPK2,H2AFX,RBMS1,DMWD,USP13,PRPF4B,NCOR2,SCAMP3,TCF3,BRAP,JMJD6,FOXO3,WWP2,ADD3,ITGB8,SUV39H2,DCP1A,GTSE1,NAP1L4,UBE3B,MAP3K14,CNPY3,MED22,HNRNPM,SMC4,NUDC,PDLIM2,STAU1,TNFAIP3,TACC1,NEK7,FBXO9,ANAPC2,LRRC1,RPL27A,DDX39A,MACF1,ZNF180,GNA12,SLC19A1,PRDX3,MFAP1,CCZ1B,HNRNPH3,PML,CCDC69,KHSRP,USF2,PURA,IER2,THOC1,AGRN,NOP2,UBN1,RBM8A,PTP4A3,NENF,KIF2C,SIRT2,USP48,CDIPT,RUFY1,BIRC2,BCAT2,DLG5,DST,SYNM,ATG3,AP3S2,IL6ST,TXLNA,RP2,EIF5,MYBL1,OGG1,ARID4A,CARM1,TRIM14,RYBP,SRPK2,PTPRK,SP3,SEPT9,PBXIP1,BAZ2A,NCK1,RAD51AP1,GMFB,CDC6,BRCA1,PBRM1,ODC1,RHEB,DPYSL3,MAN2A2,AGPAT2,ZNF268,STK11,ROCK1,GALNT10,CLU,FAM208A,ATP6V0E1,NUMB,SLC12A7,LZTR1,DNAJB2,UBXN1,CIB1,ASAH1,CDK13,SRRT,TTF1,NUP205,TNS3,NFATC3,KIF13B,TIMELESS,RBM3,AFF1,BCL2,TMEM8A,CYTH1,NSDHL,ARMC8,DAPK3,RBM38,RXRB,NAP1L1,GOLGA4,PCM1,SNRNP70,PDSS2,APOL2,SMARCD1,USP7,WASF2,SART1,FEZ2,RPLP2,MPHOSPH8,SLC2A1,PLAGL2,RRAGC,IRF3,DUSP22,GGPS1,CHD1,CSDE1,SEC11A,ZNF473,TNFAIP8,KIF14,F2R,FAM3A,CTDSP2,HTRA2,SPSB3,ARHGAP17,BTG2,OGDH,DCLRE1C,MBD3,FANCE,RBL1,TIMM17A,TULP3,STAT6,GADD45B,CANT1,SCARB1,H3F3A,MAPK1,ABCA1,TSPAN5,SMAD4,PARD3,KIF3B,GOLIM4,CASP6,DBF4,PAWR,HMGN3,MXD4,MYO9B,GGA2,SLC12A9,CSNK1A1,NCAPG,PIP4K2A,KIF5B,GTPBP3,FGFR3,CTSS,CTNNBL1,KLHL20,SEC24C,PPIG,RRBP1,POLR1B,SLC25A1,TGFB1,ZNF202,ZMYM5,TOP3A,RANGAP1,PRMT2,CDK11A,TFEB,TPD52L2,UPF1,ATP6V1D,NEK1,TRIM26,TFE3,ZC3H7B,CTBS,RBPJ,PLOD3,ZMIZ1,UBE2C,IFI16 |
| 7.445e-13 | -27.93 | GSE9878_CTRL_VS_EBF_TRANSDUCED_PAX5_KO_PRO_BCELL_DN | MSigDB lists | GSE9878_CTRL_VS_EBF_TRANSDUCED_PAX5_KO_PRO_BCELL_DN | 188 | 68 | 17377 | 2626 |
THOC1,URB2,POC1A,SUZ12,RBM8A,TPX2,SLC29A1,NANS,SNN,POLR3K,PAIP1,SAP130,ZNF428,RAB35,NUP107,CDC25B,APOOL,GPD1L,METTL1,TDP1,CDC123,KIAA0040,WDHD1,ELP4,NLN,BRCA1,GSTCD,PLEKHF2,GEMIN5,MAP3K4,CHCHD1,WDR4,BEND3,ZBTB11,DHPS,CENPF,DBF4,NKRF,RBM34,BDH1,PRC1,CLDND1,GTF2H2,UBE2M,TIMM8B,ADAM17,ZFP64,ANKRD37,AACS,WDR18,MRS2,USP42,KIAA0930,SSR2,CCDC34,PDE3B,KIF11,APPL1,AKAP1,EPRS,KIF18A,MTHFD2,KPNA4,TXNDC16,FAM3C,OAZ2,WDR62,BYSL |
| 8.185e-13 | -27.83 | mitochondrial envelope | cellular component | GO:0005740 | 710 | 176 | 18223 | 2701 |
COX15,MTX3,NDUFB6,MRPS15,UQCR10,ABCB10,ATP5PF,BECN1,MRPL19,PARK7,SLC25A37,TIMM23,GOT2,SLC44A1,DNM2,HADHB,NDUFB9,CISD2,MRPL32,TRIM14,MRPL57,TIMM50,BAK1,MRPL43,MRPL12,MCL1,SLC25A22,COA7,SLC25A5,FOXRED1,MPC1,STOML2,TIMM13,RPS27A,TIMM29,MRPL27,MPV17,COX5A,UQCRH,CLU,DHFR2,MRPL13,SLC25A33,NDUFV2,COX5B,MRPL9,MRPS2,PHB2,CHCHD2,NDUFA4,COX4I1,CYCS,PSEN1,NDUFS7,NDUFS4,NDUFAF6,TIGAR,BDH1,SLC25A51,BCL2,MRPL40,MRPL48,CYC1,ALDH18A1,MRPL21,TIMM8B,ATP5IF1,COQ8A,NOA1,PGS1,ACSL3,MRPL16,MTX1,TOMM40,SFXN5,CYB5A,AKAP1,SDHB,CAT,COX7A2L,ATP5F1A,NIPSNAP2,TMEM14A,MRPL3,NDUFA5,TOMM20,ATXN3,IMMT,NDUFAF2,RAF1,MRPL39,STARD7,BCL2L1,SLC25A44,SNN,LYN,SDHA,MIEF1,MOAP1,MRPL50,MRPL34,MRPS27,PARL,MICU2,MAVS,APOOL,ATF2,TMEM14C,HTRA2,PPIF,ACSL5,COQ10B,CPOX,VDAC2,DMAC2,NLN,OGDH,NDUFA7,NDUFB1,VDAC1,TAZ,MRPS14,GFER,ANKZF1,CHCHD3,MRPL2,DAP3,MRPL55,TOMM6,CHCHD1,TIMM17A,NDUFA11,SLC25A39,CDS2,NDUFS1,MRPL42,MRPS26,SLC25A12,LETMD1,TIMM21,ATP5F1B,SLC25A43,FOXO3,SLC25A36,NDUFV1,NDUFA2,COQ4,NDUFB4,CRAT,MRPL54,NDUFS8,MRPL11,NDUFA3,STAT3,MTX2,RNF5,SLC25A1,COA3,TIMMDC1,TMEM126B,MRS2,ABCF2,MRPS10,ATP5MF,RHOT1,RHOT2,GUF1,CHCHD6,SH3GLB1,MFN2,ATP5MC3,COX8A,SLC25A19,NDUFS5,ACADM,HIGD2A |
| 8.493e-13 | -27.79 | regulation of mitotic cell cycle | biological process | GO:0007346 | 684 | 174 | 17256 | 2622 |
HECA,FGFR1OP,UBE2E2,PDCD6IP,GPR132,KMT2E,CUL1,SIRT2,CCNB1,BECN1,FANCI,CDKN2C,PCNA,PSMD1,NEK6,ECD,CDC25B,TACC3,CARM1,PLK1,PLK3,AATF,RBX1,MKI67,MRNIP,CDC6,LRP5,USP22,AURKB,BRCA1,ANLN,SOX4,MAP3K4,RPS27A,PSMD8,E2F4,ZNF268,CHEK2,VPS4A,TFDP2,SLF1,PSMC1,MAPRE1,CLSPN,PHB2,CENPF,TOP2B,HAUS4,CDK13,PSMD9,CNOT11,HAUS2,CDC73,CNOT3,DTL,TFAP4,PDXP,RB1,SMC3,CCP110,FBXO7,MSH2,BCL2,FBXL7,KNTC1,MCPH1,PSMA1,MAP4K3,MAP2K2,DAPK3,PSMB3,PSMC4,HAUS8,PCM1,CDC27,DUSP3,ODF2,CDCA5,NUP62,CNOT6,NDE1,ZNF830,CDK2,CDKN2A,ZNF207,CHMP2A,CYLD,DYNLL1,PTTG1,TPX2,BCL2L1,PRKACA,APP,PSMA6,MDM2,KIF14,PIN1,NABP1,CDKN1B,CEP63,ATF2,CTDSP2,DCTN1,TIMP2,BRD4,PSRC1,PSMA8,BTG2,TAOK1,MAP4K4,INTS13,PSMB7,CUL3,NUSAP1,PKMYT1,CDC23,CHMP2B,PSMB9,RAD51C,CDC16,RBL1,NSMCE2,PSMD3,CHMP4B,XRCC3,GEN1,TUBB,CSNK1D,RAE1,MECP2,CDT1,CDK2AP2,DCTN2,CDK11B,BLM,RAB11A,MAD2L2,FBXO5,RPA2,RFWD3,PSMD2,PTEN,CENPJ,PTPN11,NABP2,GTSE1,BRD7,H2AFY,MAP3K14,CNOT6L,TGFB1,PPP1R9B,ADAM17,NEK7,PRKDC,PRMT2,BORA,KIF11,CDK11A,HSPA1B,CNOT9,NEK1,BIRC5,TFDP1,PML,E2F1,SSNA1,PKD2,UBE2C,HRAS,ESPL1,SLF2,ANAPC4,DDB1 |
| 9.078e-13 | -27.73 | UBE2I (ubiquitin conjugating enzyme E2 I) | protein interactions | 7329 | 453 | 133 | 17029 | 2761 |
RORB,NOP2,TSC22D3,XIAP,SND1,UBE2I,PARK7,CREM,PA2G4,NUP210,ETV6,NUP153,ZNRD1,SEH1L,CARM1,CDC37,SP3,SNRNP200,LNX2,TOPORS,AURKB,BRCA1,PRKRA,SOX4,WAS,RAD18,CHD3,AAAS,SSRP1,AGTRAP,UBXN1,DHX9,MEF2A,TOP2B,SUPT7L,XPO7,PSMD9,NUP205,LMNA,DTL,RB1,HDAC7,BCL2,NUP85,TERF2,ZMYND11,KRAS,EXOSC9,SEPT7,ELK1,MATR3,XRCC5,HMGN2,FAS,GOLGA2,RBM25,SIAH2,PIAS2,CDK2,CDKN2A,NDC1,TRIM41,SART1,SARNP,DNMT3A,FOXM1,SUZ12,SLC2A1,SUMO2,MYH9,NSD3,APP,ZNF420,MDM2,SP100,SIAH1,NVL,MTA1,GMEB1,SOCS6,NUP107,CDKN1B,ATF2,BIRC3,ATXN1,NUP155,EDF1,NDUFA7,TRIM28,MAT2A,RAD54B,SRSF1,SUGP1,TAB2,HIPK2,UHRF2,STAT1,RBMS1,CHMP4B,FUS,SMAD4,CBX4,NCOR2,HABP4,TCF3,CDCA8,TKT,JMJD6,BLM,ETS1,WWP2,CAPN2,ADD3,NDUFA2,PTEN,KMT5A,CREB1,HNRNPM,DDX24,KAT2A,PRKDC,RPL8,COG1,RANGAP1,SYMPK,SH3GLB1,HGS,ZHX1,PML,DDX5,TAF12,TATDN1,HIPK3 |
| 9.892e-13 | -27.64 | SRPK3 (SRSF protein kinase 3) | protein interactions | 26576 | 60 | 34 | 17029 | 2761 |
CDC40,NOP2,RRP15,SRSF6,DHX9,EBNA1BP2,THRAP3,BRIX1,PCBP1,KRR1,RBM34,SRSF4,EXOSC1,FTSJ3,HNRNPM,STAU1,SNRPB,SREK1,LLPH,PRKRA,GAR1,LUC7L,SNRPA,DHX15,CAND1,SRSF1,CCDC86,HNRNPR,RBMX,SRSF3,SNRNP70,PDCD11,PRPF4B,CCDC137 |
| 9.934e-13 | -27.64 | GSE21063_WT_VS_NFATC1_KO_8H_ANTI_IGM_STIM_BCELL_UP | MSigDB lists | GSE21063_WT_VS_NFATC1_KO_8H_ANTI_IGM_STIM_BCELL_UP | 189 | 68 | 17377 | 2626 |
TMEM106C,POLA2,WDYHV1,POC1A,UCK2,TPX2,NUF2,KIF2C,LACTB2,CCNB1,ATP6V1B2,KIFC1,CALM2,CCNA2,NUP210,CCDC50,IARS,UCHL5,SRI,AP2B1,KIF22,TCEA1,CLN6,GM2A,TACC3,SAP30,RFC3,CPOX,MKI67,KIF15,CDCA2,CDC6,AURKB,ANLN,ASF1B,PRIM1,KIF18B,ZNF367,H2AFX,MBOAT1,CHEK2,TSPAN5,TUBB,RHEBL1,MCM10,HJURP,ACAP1,DBF4,SPAG5,FBXO5,DTL,SUV39H2,MCM5,BDH1,PRC1,MAPKAPK3,ASPM,SEPT8,KIF11,STYXL1,TARS,BIRC5,PRPS2,TFDP1,FAM83D,FAM126A,TMEM14A,FAF1 |
| 1.032e-12 | -27.60 | peptidyl-lysine modification | biological process | GO:0018205 | 300 | 94 | 17256 | 2622 |
NDC1,NUP188,ASH1L,KMT2E,SUZ12,CXXC1,SUMO2,NSD3,TAF6L,SIRT2,UBE2I,PARK7,MEAF6,TET3,PCNA,NUP210,MDM2,KMT5C,BRPF3,MTA1,NUP107,NUP153,TAF5L,ATF2,SENP1,ARID4A,SEH1L,SP3,KAT7,EHMT1,ELP4,KIAA1586,WDR82,TOPORS,NUP155,USP22,AURKB,KMT2C,MBD3,TRIM28,DOT1L,NSMCE2,CAMKMT,OGT,VIPAS39,BEND3,NCOA1,NAA60,CBX4,AAAS,DHPS,EYA1,MECP2,RAE1,NUP54,CDCA8,JMJD6,TOP2B,EZH1,WDR5,SUPT7L,RLF,NUP205,IRF4,SUV39H2,KMT5A,HDAC7,ZNF335,NAA50,CTR9,KANSL2,NUP85,EIF5A,KAT2A,LDB1,RTF1,RANGAP1,NFATC2IP,METTL22,MEN1,KDM3A,MBIP,BIRC5,SETD3,TEX30,PIAS2,KMT2B,NUP62,RUVBL2,TAF12,PLOD3,NUP58,SGF29,GCSH |
| 1.101e-12 | -27.54 | Metabolism of proteins | REACTOME pathways | R-HSA-392499 | 1619 | 367 | 10287 | 1696 |
TMED7,RAB14,H2AFZ,TXN,NUP188,ADD1,PRKCSH,PIGQ,CXXC1,NANS,UBE2I,RPL23A,CALM2,NAPG,PSMD1,RAB4A,RAD23B,FBXW2,NUP153,TFG,SENP1,MGAT5,SEH1L,USP34,SRP72,USO1,TMEM115,GNG7,AURKB,SLC17A5,AMDHD2,GALNT7,USP22,MCFD2,ICMT,RAB22A,EIF3A,RAB2B,ARF4,SMAD2,TMED10,STT3A,RPS27A,PSMD8,AXIN1,RPS14,OGT,ST3GAL2,FBXL3,SMAD1,ARRB2,LONP2,CCDC59,AAAS,B4GALT2,DDX58,CLSPN,DHPS,GGA1,SEC61G,GSPT2,RAB23,B4GALT1,TOP2B,TMED3,PSMD9,PARN,COPG2,CDC73,LMNA,WDR48,COPB2,CD59,RPN1,EIF2S2,EXOSC7,SMC3,DAD1,HDAC7,PIGG,CYC1,MYDGF,RNF135,GNAI2,NUP85,PABPC1,PPP6R1,TMED2,EEF1D,EIF5A,TIMM8B,EIF3L,PIGT,FOXK1,MAN1B1,ERO1A,RPS10,RPS24,SSR2,USP10,EXOSC9,ADRB2,MTX1,TOMM40,GOSR1,EIF4H,CCT8,PSMB3,SEC31A,DERL1,PFDN5,GOLGA2,NSF,PIAS2,YY1,PPP6R3,RNF139,NUP58,CDKN2A,EXOC3,NDC1,ABCA3,ATXN3,RAB11B,EIF3D,ANK3,INO80E,GNB2,STAM,APP,PHC2,RAB21,CCNA2,SHC1,SP100,SIAH1,UCHL5,MTA1,NUP107,MAVS,DCTN1,CCT2,SEC61B,VDAC2,RPL38,RAB1A,PSMB9,TAZ,SERP1,CHCHD3,EIF3K,SEC61A1,DDOST,RAB24,NSMCE2,CAMKMT,SEL1L,H2AFX,RPLP1,ATF6,B4GALT3,XRCC4,CSNK1D,DYNC1LI2,USP13,OTUD5,RPS2,B4GALT5,BABAM1,SLC25A12,ATP5F1B,BLM,RAB11A,MAT2B,PSMD2,PTEN,RPL17,ARF5,FUT8,AXIN2,RPL19,ST8SIA2,MTX2,RPL22L1,SPTAN1,TNFAIP3,KAT2A,USP42,RPL8,OTUD3,RHOT1,RPL27A,ARSK,RPA1,YIF1A,HGS,KEAP1,RPL32,MAGT1,PFDN4,TATDN2,PML,KHSRP,ASNA1,ADA2,PIGM,COPA,MOGS,UBE2Z,DNAJC24,CSNK2A1,USP48,BECN1,SEC16A,BIRC2,RNF103,SSR1,RAB8A,NUP210,PCNA,TIMM23,RAB35,JOSD1,EIF5,TIMM50,SP3,EXOSC6,DPM1,SUMF2,BRCA1,RAB5B,USP21,PAF1,ALG3,MAN2A2,RPL37,TIMM13,MIA2,ACTB,GALNT10,NGLY1,RPS26,PSMC1,UBE2D3,RPS15,PIGN,NSMCE4A,GORASP1,UBXN1,CHCHD2,RPL15,RAB6A,B4GALT4,ASXL2,TTF1,NUP205,C1GALT1,UBE2Q2,NUS1,CCP110,CTR9,ZRANB1,ATP6V0D1,KDELR1,PREB,TRAPPC9,TSTA3,GBA,RPL6,PSMA1,RTF1,SYVN1,METTL22,LY6E,RPL36,PSMC4,GALNT2,UAP1,EXOC4,SIAH2,FN3KRP,NUP62,CTSA,ATP5F1A,NANP,USP7,TOMM20,CYLD,GNPNAT1,RPLP2,DYNLL1,SUMO2,COPE,RPL11,USP5,RAD23A,ANKRD28,SEC11A,BABAM2,MDM2,PSMA6,ABRAXAS2,EXOSC1,CS,PPP6C,RPN2,LMAN1,PDIA6,CTDSP2,RPL29,RPL35,BIRC3,PSMA8,RAB7A,PSMB7,NUP155,KDM1B,VDAC1,EDEM2,EIF3G,GFER,RPS9,RPSA,EIF3H,IDE,TIMM17A,PSMD3,TOMM6,USP11,FAU,H3F3A,SMAD4,CBX4,CMAS,RAE1,GNE,DCTN2,CDCA8,NUP54,TIMM21,SMC6,SUMF1,ARF1,GGA2,DNAJB9,MAN1A1,KIF5B,SEC24C,STAT3,SLC35A1,RNF5,MYO5A,TGFB1,MLEC,CNTN5,RHOA,PRKDC,COG1,RANGAP1,NEU1,RAB18,SEC23IP,BIRC5,USP20,MBD6,SPCS3,UBE2C |
| 1.110e-12 | -27.53 | GO_HYDROLASE_ACTIVITY_ACTING_ON_ACID_ANHYDRIDES | MSigDB lists | GO_HYDROLASE_ACTIVITY_ACTING_ON_ACID_ANHYDRIDES | 777 | 191 | 17377 | 2626 |
RAB14,DDX47,ABCC10,YTHDC2,TAP1,DHX8,ABCB10,KIF2C,KIFC1,RAB8A,RAP1A,CDC42,EIF4A3,RAB35,XRCC2,RAB4A,ATP13A3,DNM2,KIF22,EIF5,ABCC5,SNRNP200,RHOBTB3,SEPT9,KIF15,DDX20,ARHGDIB,MCM2,RFC2,RAB5B,LSG1,RAB22A,DHX15,RAB2B,ARF4,GINS4,RHEB,RAD18,KIF18B,CHD3,MYO18A,ATP6V0C,CLU,VPS4A,NUDT11,PSMC1,LONP2,ATP6V0E1,DDX42,DDX58,RECQL,CHTF18,GSPT2,DHX9,RAB23,KLC1,KIF23,TOP2B,RAB6A,MYL6B,DDX56,SMC3,MCM5,KIF13B,EFTUD2,MSH2,ATP6V0A2,GNAI2,ATP6V0D1,PPA1,ABCC1,DDX28,NTPCR,NOA1,DHX29,NUDT4,GTPBP4,KRAS,RIT1,EIF4H,ABCF1,CCT8,RHOB,PSMC4,XRCC5,GNAS,NSF,RUVBL2,RBBP4,MYO9A,NUDT3,RHOG,ABCA3,RAB11B,DYNLL1,CHD1L,RAC1,PMS2,OLA1,MYH9,SMARCA4,RRAGC,ATP6V1B2,GNB2,CHD1,RAB21,ATP6V0B,ATP2A2,RALB,KIF14,DUT,PIN1,TAP2,TOP1MT,DNAL4,DCTN1,ATP6V1G1,ENPP4,RFC3,ATP13A1,RAB7A,ATP6V0A1,RAB1A,DHX57,RAD54B,DDX17,KIF2A,RAD51C,IDE,ATP1A1,ACYP1,DHX16,RAB24,PPA2,CANT1,XRCC3,ABCA1,DYNC1LI2,TUBB,RAD51D,POLQ,KIF3B,SHPRH,TOR3A,DCTN2,MYO9B,ARF1,BLM,RAB11A,GFM2,WRNIP1,KIF5B,GTPBP3,STARD9,ARF5,ANXA5,DDX31,ABCD1,GTF2H2,MSH6,MYO5A,GINS1,RHOA,LONRF3,DDX24,HELB,BTAF1,ATP2C1,ABCF2,TUFM,RHOT1,DDX39A,GUF1,KIF11,MACF1,RHOT2,HSPA1B,MYO1F,DDX23,MFN2,RAB18,GNA12,UPF1,ATP6V1D,KIF18A,ATAD2,DDX5,ASNA1,ATP6V1C1,HRAS,DDX52 |
| 1.155e-12 | -27.49 | proteolysis involved in cellular protein catabolic process | biological process | GO:0051603 | 556 | 148 | 17256 | 2622 |
PDCD6IP,CUL1,UBE2Z,NHLRC3,SIRT2,UBQLN2,CCNB1,UBE2I,USP48,BIRC2,RNF103,FBXO22,PCYOX1L,PSMD1,RAD23B,PCBP2,USP34,PLK1,RBX1,TOPORS,USP22,AURKB,CCNF,USP21,RPS27A,PSMD8,AXIN1,ATE1,ARRDC1,VPS4A,KLHL42,FBXL3,ARRB2,NGLY1,PSMC1,LONP2,UBE2D3,RMND5A,TMUB1,UBXN1,KCTD17,ZNRF3,PSMD9,VPS25,RHBDD1,NPLOC4,DTL,RNF121,ZNRF2,FBXO7,FBXL7,ZRANB1,ERLIN1,MAN1B1,PSMA1,USP10,UBE4B,SYVN1,ARMC8,PSMB3,ISG15,PSMC4,DERL1,CDC27,KLHL15,SIAH2,DCAF11,USP32,CTSA,ECPAS,RNF139,USP7,ATXN3,CYLD,UBR2,PTTG1,RAD23A,USP5,UBXN2A,MDM2,PSMA6,SIAH1,UCHL5,KIF14,MTA1,NSFL1C,SOCS6,ANAPC7,TTC3,SPSB3,PRPF19,RLIM,SEC61B,PSMA8,PSMB7,CUL3,CDC23,EDEM2,TOLLIP,PSMB9,USP36,BTBD1,ANKZF1,DNAJC10,IDE,CDC16,UBXN2B,PSMD3,ARNTL,SEL1L,RNF38,CHMP4B,TRIM32,USP11,SMURF1,USP13,TRIP12,UBE4A,SDF2L1,CSNK1A1,DNAJB9,WWP2,CAPN2,PSMD2,CTSS,KLHL20,LTN1,GTSE1,FBXL19,RNF5,TNFAIP3,USP42,FBXO9,RFFL,ANAPC2,WDR81,CTSL,FBXO21,KEAP1,PLAA,PML,PPP1R11,USP20,WDR91,UBE2C,ANAPC4,FAF1,DDB1 |
| 1.203e-12 | -27.45 | cellular protein catabolic process | biological process | GO:0044257 | 586 | 154 | 17256 | 2622 |
PDCD6IP,CUL1,UBE2Z,NHLRC3,SIRT2,UBQLN2,CCNB1,UBE2I,USP48,BIRC2,RNF103,FBXO22,PCYOX1L,PSMD1,RAD23B,AP2B1,PCBP2,USP34,PLK1,RBX1,TOPORS,USP22,AURKB,CCNF,USP21,RPS27A,PSMD8,AXIN1,ATE1,ARRDC1,CHEK2,VPS4A,KLHL42,FBXL3,ARRB2,NGLY1,PSMC1,LONP2,UBE2D3,RMND5A,TMUB1,UBXN1,KCTD17,ZNRF3,PSMD9,VPS25,RHBDD1,NPLOC4,DTL,RNF121,ZNRF2,FBXO7,FBXL7,ZRANB1,ERLIN1,MAN1B1,PSMA1,USP10,UBE4B,SYVN1,ARMC8,PSMB3,ISG15,PSMC4,DERL1,CDC27,KLHL15,SIAH2,DCAF11,USP32,CTSA,ECPAS,RNF139,USP7,ATXN3,CYLD,UBR2,PTTG1,RAD23A,USP5,UBXN2A,MDM2,PSMA6,SIAH1,MTA1,UCHL5,KIF14,NSFL1C,SOCS6,ANAPC7,TTC3,SPSB3,HTRA2,RLIM,PRPF19,SEC61B,PSMA8,PPT1,RAB7A,PSMB7,CUL3,CDC23,EDEM2,TOLLIP,PSMB9,USP36,BTBD1,ANKZF1,DNAJC10,IDE,CDC16,UBXN2B,PSMD3,ARNTL,SEL1L,RNF38,CHMP4B,TRIM32,USP11,SMURF1,AP2S1,USP13,TRIP12,UBE4A,SDF2L1,CSNK1A1,DNAJB9,WWP2,CAPN2,PSMD2,CTSS,KLHL20,LTN1,GTSE1,FBXL19,RNF5,TNFAIP3,USP42,FBXO9,RFFL,ANAPC2,WDR81,CTSL,FBXO21,KEAP1,PLAA,PML,PPP1R11,USP20,WDR91,UBE2C,ANAPC4,FAF1,DDB1 |
| 1.208e-12 | -27.44 | MAGOH (mago homolog, exon junction complex core component) | protein interactions | 4116 | 190 | 71 | 17029 | 2761 |
SARNP,XAB2,SUZ12,SF3B1,RBM8A,MYH9,SNRPD3,SF3B2,EIF4A3,SRSF4,TRA2B,CORO1A,AQR,CHTOP,SRSF10,SRPK2,PRPF19,CDC5L,FYTTD1,SNRNP200,SNRPB,PPIE,CRNKL1,HNRNPF,RNPS1,PFKFB3,MCM2,SLC25A5,RPS9,DHX15,CLNS1A,SRSF1,DDX17,JAK1,STK38,ACTB,NKAPD1,PRPF4B,CDC40,RPS2,R3HCC1L,SRSF6,RPL15,THRAP3,BLM,SCYL2,ERH,RPL17,EFTUD2,CAPZA1,YBX1,RBM3,RPL19,FBL,HNRNPM,SPTAN1,YTHDC1,RPL8,ILF3,RPL6,RPS24,SRSF5,RPL27A,MATR3,PHF6,PRDX1,UPF1,GOLGA2,RBMX,SRSF3,SNRNP70 |
| 1.219e-12 | -27.43 | BARD1 (BRCA1 associated RING domain 1) | protein interactions | 580 | 271 | 91 | 17029 | 2761 |
BCCIP,UBE2E2,MAGED1,HNRNPUL2,OLA1,FKBP2,AP1B1,ZNF121,BABAM2,NSRP1,SRSF4,AKAP8,TRA2B,STRAP,CDK12,CCAR1,PCBP2,SRSF10,SRPK2,CSTF1,CDKN2AIP,SNRNP200,KAT7,SNRPB,ELOA,CIRBP,DDX20,AURKB,BRCA1,RFC2,LUC7L,FKBP3,DHX57,SRSF1,GEMIN5,HSPA4,CHD3,LUC7L3,E2F4,PPM1G,U2SURP,H2AFX,BEND3,PDXK,MAPK1,UBE2D3,EWSR1,ZNF768,SRSF6,UBXN1,NKRF,CDK13,THRAP3,WDR5,PARN,SPAG5,FBXO5,RBM17,KRI1,CCNK,FKBP1A,MSH2,GTSE1,BRD7,YBX1,BCL2,GEMIN4,MICAL3,LUC7L2,MSH6,HP1BP3,MOB4,ZFP64,TACC1,MTA2,BCLAF1,SRSF5,POLR2A,CBX3,XRCC5,GOLGA2,RBM25,ZHX1,MFAP1,PARG,KBTBD7,E2F1,YWHAZ,SNRNP70,CDK2,HNRNPDL |
| 1.238e-12 | -27.42 | MDC1 (mediator of DNA damage checkpoint 1) | protein interactions | 9656 | 194 | 72 | 17029 | 2761 |
IMMT,ATXN3,SUMO2,HNRNPUL2,COPE,CSNK2A1,SMARCA4,C2orf49,SSR1,MDM2,BABAM2,ATP2A2,ANAPC7,CDC5L,SRPK2,CDKN2AIP,RPL29,SNRPB,VDAC2,MKI67,SLC25A22,BRCA1,CDC23,PRKRA,COA7,VDAC1,RFC2,SRSF1,PRIM1,PPP2CA,CHCHD3,PAF1,CDC16,SEC61A1,U2SURP,H2AFX,CHEK2,CLU,PHB2,ZNF768,BABAM1,THRAP3,LMNA,RBM17,LYAR,TFAP4,RPA2,SSBP3,BANF1,PELO,CAPZA1,TAGLN2,CPSF4,LPCAT1,MCPH1,MICAL3,STAU1,PRKDC,WDR18,ANAPC2,MPG,PCGF1,POLR2A,CBX3,XRCC5,RPA1,CDC27,BIRC5,OSBPL8,YWHAZ,ANAPC4,SMARCD1 |
| 1.291e-12 | -27.38 | MORF_RAF1 | MSigDB lists | MORF_RAF1 | 108 | 47 | 17377 | 2626 |
UBE2D3,MRPL9,NUP188,HNRNPAB,UBN1,PRKCSH,RAF1,PDAP1,SUMO2,NACA,TOR1AIP1,RAC1,UBE2I,AP3S1,SRRT,SLC25A36,TERF2IP,HNRNPA2B1,DNAJC8,CAPZA1,HADHB,CS,NAP1L4,MORC3,KDM3B,CSNK1G2,SNRNP200,SEC61B,JTB,GMFB,NFATC2IP,RAB1A,DDX39A,EIF4H,POLR2A,MFN2,PPP2CA,SYNCRIP,COX7A2L,ATXN2L,COX8A,NUP62,YWHAZ,IDH3B,DDB1,CSNK1D,SMNDC1 |
| 1.363e-12 | -27.32 | VECCHI_GASTRIC_CANCER_EARLY_UP | MSigDB lists | VECCHI_GASTRIC_CANCER_EARLY_UP | 381 | 111 | 17377 | 2626 |
SKA3,FOXM1,PTTG1,TPX2,DHX8,SMARCA4,EBNA1BP2,NUF2,LACTB2,COMMD5,CCNB1,FANCI,CCNA2,KIF14,POP7,CDC25B,SMARCE1,CDK12,RFC3,POLR2G,AATF,RAD51AP1,PBK,SNRPB,MKI67,KIF15,RRM2,NUSAP1,NUP155,CDCA2,CDC6,ABHD11,BRCA1,KDM1B,ANLN,GSTCD,MCM2,ARL5B,EML4,GINS4,RAD54B,ANKRD10,TRIM47,TIMM13,RAD18,KIF18B,TIMM17A,ZNF367,CEP55,PRPF4,ANP32E,PIEZO1,RRS1,MRPL13,XRCC4,LRP8,PFKP,FUBP1,INTS2,HSPH1,MZT1,MCM10,DEPDC1,KLHL21,SCYL1,TRMT6,CENPF,RACGAP1,NCAPG,SAC3D1,WRNIP1,DTL,C12orf10,LYAR,MCM5,EFTUD2,PRC1,GTSE1,CYC1,CENPM,TNRC18,S100A6,SMC4,SPTAN1,GINS1,NTPCR,TK1,NASP,RBM42,ASPM,GTPBP4,MYBL2,RPL8,MRPS10,BMS1,FAM133B,MATR3,ISG15,PDCD6,ATAD2,BIRC5,PFDN4,TFDP1,CDCA5,PGRMC1,RUVBL2,IDH3B,CCNB2,UBE2C,BYSL,ZNF511 |
| 1.372e-12 | -27.31 | V$YY1_02 | MSigDB lists | V$YY1_02 | 228 | 77 | 17377 | 2626 |
ZNF207,UBL3,IER2,ASH1L,PRKCSH,WDR13,ENSA,BCL2L1,C19orf48,RUFY1,CSDE1,CDKN2C,USF1,KDM2A,TBC1D14,FIZ1,CNPY4,TRA2B,ZBTB22,RNF26,CHTOP,ARID4A,SLC39A9,DEAF1,ZNF524,MIOS,KIF15,RAB1A,DHX15,IWS1,MAP3K4,PPP2CA,UBTF,VEZF1,DAP3,TBC1D17,PSMD8,ZNF689,LUC7L3,FASTK,ATE1,BTF3,PRPF38B,ADO,NACA,STRN4,TIA1,CTCF,MYNN,ARF1,AKT1S1,ASXL2,FOXO3,CNOT3,CCNK,TFAP4,ERH,VASP,LYPLA2,RBM15B,B3GALT6,NASP,POLK,JTB,TOP3A,FBXO9,SEPT7,NDRG3,NCDN,TSC1,OSBPL11,ODF2,GLG1,SRSF3,TAF6,NUDT3,N4BP2L2 |
| 1.428e-12 | -27.28 | regulation of autophagy | biological process | GO:0010506 | 306 | 95 | 17256 | 2622 |
PRKAB1,FEZ2,TSC2,KDM4A,RRAGC,SIRT2,UBQLN2,ATP6V1B2,PRKACA,BECN1,TRIM65,PARK7,EPM2A,CDK5,ABL2,RAB8A,ATP6V0B,RALB,TBC1D14,PIK3R2,CISD2,HTRA2,DRAM2,MLST8,ATP6V1G1,CDC37,WDR41,PLK3,UBQLN4,ULK3,LARS,TRIM8,ATP6V0A1,MCL1,VDAC1,RHEB,USP36,OPTN,CHMP4A,VPS26B,TAB2,CHMP4B,ATP6V0C,TICAM1,STK11,ROCK1,SMURF1,ATP6V0E1,CAPN1,USP13,SVIP,TBC1D12,SCOC,PHF23,DAP,PRKAA1,LAMTOR3,EIF2AK4,PIP4K2A,TIGAR,FBXO7,DAPK1,ATP6V0A2,BCL2,ATG13,PIKFYVE,LRSAM1,ATP6V0D1,TPCN1,RNF5,ATP5IF1,RB1CC1,PIP4K2C,GBA,USP10,ADRB2,EIF4G2,DAPK3,RMC1,SH3GLB1,MAPK3,TFEB,MFN2,MTMR3,TSC1,ATP6V1D,GOLGA2,LAMTOR4,EXOC4,CTSA,PSAP,ATP6V1C1,SNRNP70,VPS29,IFI16 |
| 1.444e-12 | -27.26 | GSE7568_IL4_VS_IL4_AND_TGFB_TREATED_MACROPHAGE_24H_DN | MSigDB lists | GSE7568_IL4_VS_IL4_AND_TGFB_TREATED_MACROPHAGE_24H_DN | 178 | 65 | 17377 | 2626 |
DNAJC2,MCM10,RWDD1,MRPS15,POLR2K,CUTA,ALKBH5,TMEM97,DNAJC24,ARFIP2,AGPAT3,WRB,SSR1,FASTKD3,MRPL50,FARSA,SNUPN,AHCTF1,NOL11,INTS7,BANF1,EFTUD2,AKAP8,ATP13A3,EXOSC1,TPST1,SUCLG2,MCPH1,MICAL3,PLK3,GUK1,KAT2A,HPDL,ERLIN1,RAD51AP1,NOL8,AMD1,RANGAP1,BCLAF1,KRTCAP2,TXNL4A,DDX39A,PSMB3,USP36,PSMC4,AKAP1,RPL36,UTP20,ALG3,HSPA4,TFDP1,RWDD4,PRMT7,DTD1,NDUFS5,KLHDC4,SCARB1,NAA20,CD81,NMD3,PDCD2L,GCSH,AAAS,ATXN7L2,FUBP1 |
| 1.473e-12 | -27.24 | GSE12845_IGD_POS_VS_NEG_BLOOD_BCELL_DN | MSigDB lists | GSE12845_IGD_POS_VS_NEG_BLOOD_BCELL_DN | 174 | 64 | 17377 | 2626 |
PPIB,CORO7,SMAP1,TXN,TMEM184B,DYNLL1,SRGN,TAP1,DNAJC24,TMED3,GYG1,SND1,CCNB1,BRIX1,TFRC,PABPC4,CFLAR,PAPOLA,MAN1A1,CDK5,CAPN2,DECR1,INTS7,PELO,ANXA5,SEPT11,RPN2,RBM3,PDIA6,MTX2,PPA1,PREB,USO1,SEC61B,CSRP1,HMGN4,NUDT4,GNG7,MRPL12,RRM2,PSMG1,KRAS,AURKB,MTX1,RAB1A,SHCBP1,PRDX1,FAS,MTHFD2,ATP1A1,SEC61A1,ORMDL2,STK38,CORO1C,ACAT1,SIL1,CTSA,SPCS3,RUFY3,ATP6V1C1,YWHAH,AP2S1,ACSF2,TUBB |
| 1.476e-12 | -27.24 | KIM_ALL_DISORDERS_CALB1_CORR_UP | MSigDB lists | KIM_ALL_DISORDERS_CALB1_CORR_UP | 516 | 139 | 17377 | 2626 |
UBL3,H2AFZ,ENSA,CUL1,UBQLN2,OAT,MAP1LC3B,SLC20A1,PPP1R16B,ABHD14A,RNF103,PRNP,CDK5,PSMD1,GOT2,RAD23B,AKR1B1,JOSD1,TECR,EIF5,ABCC5,SRPK2,COPS8,USO1,KLF10,SNRPB,GMFB,ZFAND5,PRPSAP1,OPTN,MAN2A2,BRD2,PSMD8,ATP6V0C,PSMC1,OAZ1,PFKP,WSB2,PPP1R12A,TM9SF4,KLC1,NCKAP1,XPO7,SUB1,ATIC,AHCY,KIFAP3,CYC1,UBE3C,ATP6V0D1,TMED2,SOCS5,TSPYL4,CREG1,ITM2A,RTF1,CAPZA2,CYFIP2,ARPC1A,EIF4H,ANKRD46,NCDN,GNAS,NSF,DUSP3,COX7A2L,MDH1,TOB1,NDUFA5,KARS,TOMM20,TMX4,KIAA0232,SUMO2,MAGED1,ATP6V1B2,MOAP1,ATP6V0B,APLP2,PSMA6,ATP2A2,PPP6C,TTC3,CLTB,GPD1L,GPX4,DCTN1,SHOC2,CCT2,EID1,IDH3A,CIRBP,VDAC2,ATP6V0A1,DNAJA1,VDAC1,RAB1A,PDHX,HINT1,DDOST,CERS6,HNRNPR,WDR7,MAPK1,AP2S1,ADAM23,MIF,SLC30A9,KIF3B,NDUFS1,SCAMP3,ANXA6,TKT,SLC25A12,ARF1,LANCL1,REEP5,RAB11A,PIP5K1C,SLC25A36,NDUFV1,AHSA1,H2AFY,CAMK2G,MOB4,FBXO9,TSR2,SH3BP5,PLD3,ATP6V1D,ELMO1,OAZ2,PGRMC1,COX8A,LRPPRC,PSAP,PREPL,ATP6V1C1,IDH3B |
| 1.574e-12 | -27.18 | KAUFFMANN_DNA_REPAIR_GENES | MSigDB lists | KAUFFMANN_DNA_REPAIR_GENES | 220 | 75 | 17377 | 2626 |
POLA2,MBD1,XAB2,PTTG1,PMS2,UBE2I,MBD4,RAD23A,FANCL,PCNA,DUT,XRCC2,RAD23B,CRY2,OGG1,TDP1,ERCC1,RFC3,RAD51AP1,RRM2,BRCA1,SMC2,DCLRE1C,RFC2,MBD3,FANCE,POLG2,RAD54B,CHAF1A,SUPT16H,RAD51C,RAD18,H2AFX,XRCC3,CHEK2,XRCC4,RAD51D,CSNK1D,SSRP1,POLQ,UBE2D3,RECQL,GADD45G,RRM1,CIB1,TOP2B,BLM,MAD2L2,NEIL2,WRNIP1,RPA2,SMC3,MBD2,XPA,MSH2,GTF2H2,N4BP2,MSH6,SMC4,TERF2,POLK,PRKDC,PARP4,TOP3A,MPG,XRCC5,RPA1,POLE,NEIL3,HMGB2,RUVBL2,RBBP4,TERF1,NUDT3,DDB1 |
| 1.603e-12 | -27.16 | GO_PROTEIN_CATABOLIC_PROCESS | MSigDB lists | GO_PROTEIN_CATABOLIC_PROCESS | 566 | 149 | 17377 | 2626 |
PDCD6IP,CUL1,UBE2Z,SIRT2,USP48,UBQLN2,CCNB1,UBE2I,BIRC2,RNF103,FBXO22,PCYOX1L,PSMD1,RAD23B,PCBP2,USP34,PLK1,RBX1,TOPORS,AURKB,USP22,CCNF,USP21,RPS27A,PSMD8,AXIN1,ATE1,CHEK2,VPS4A,FBXL3,CLN3,ARRB2,NGLY1,PSMC1,LONP2,UBE2D3,TMUB1,DNAJB2,UBXN1,KCTD17,ZNRF3,PSMD9,VPS25,RHBDD1,NPLOC4,DTL,RNF121,FBXO7,FBXL7,UBE3C,ZRANB1,LRSAM1,ERLIN1,MAN1B1,PSMA1,USP10,UBE4B,SYVN1,PSMB3,ISG15,PSMC4,DERL1,CDC27,KLHL15,SIAH2,USP32,CTSA,RNF14,RNF139,USP7,ATXN3,CYLD,UBR2,PTTG1,ANKIB1,RAD23A,USP5,UBXN2A,PSMA6,MDM2,SIAH1,UCHL5,KIF14,MTA1,NSFL1C,SOCS6,ANAPC7,TTC3,RNF19A,CLN6,HTRA2,PRPF19,RLIM,SEC61B,PSMA8,PPT1,RAB7A,CUL3,PSMB7,CDC23,EDEM2,PSMB9,USP36,ANKZF1,DNAJC10,IDE,CDC16,PSMD3,UBXN2B,ARNTL,UHRF2,SEL1L,RNF38,CHMP4B,TRIM32,USP11,SMURF1,USP13,TRIP12,KLHL21,SDF2L1,UBE4A,CSNK1A1,DNAJB9,WWP2,CAPN2,HERC3,PSMD2,CTSS,KLHL20,HUWE1,GTSE1,UBE3B,FBXL19,LYPLA2,RNF5,TNFAIP3,USP42,RFFL,FBXO9,ANAPC2,FBXO21,KEAP1,PML,USP20,UBE2C,FAF1,DDB1,ANAPC4 |
| 1.633e-12 | -27.14 | nuclear chromosome part | cellular component | GO:0044454 | 551 | 144 | 18223 | 2701 |
POLA2,MAX,H2AFZ,THOC1,CSNK2A1,SIRT2,CCNB1,UBE2I,MIS12,USF1,PCNA,MCMBP,SMARCE1,CDC5L,PLK1,ERCC1,GABPA,RAD51AP1,WDHD1,WDR82,PBRM1,AURKB,BRCA1,MCM2,GINS4,ASF1B,PRIM1,CHAF1A,BRMS1,SMAD2,TONSL,CHD3,E2F4,BAZ1B,ACTB,SINHCAF,POT1,HDAC2,DHX9,MEF2A,ASXL2,CDC73,ARID1B,YY1AP1,RB1,SMC3,MCM5,MBD2,XPA,MSH2,BUD31,TIMELESS,TERF2,PHF10,ETV3,PRIM2,MTA2,LDB1,ARID1A,APPL1,XRCC5,NSMF,SETD3,RBMX,CDCA5,APPL2,RUVBL2,YY1,RBBP4,SMARCD1,TCF12,DNMT3A,MPHOSPH8,SUZ12,SMARCA4,NUF2,INO80E,ORC1,MXD1,TERF2IP,SAP130,SP100,KMT5C,UCHL5,NABP1,TARDBP,TOP1MT,PRPF19,WBP2,NFATC2,DCLRE1C,MEF2D,H2AFV,MBD3,GAR1,TRIM28,DSN1,STAT6,STAT1,UHRF2,H2AFX,XRCC3,ANP32E,BEND3,NCOA1,H3F3A,SMAD4,RAD51D,NCOR2,MCM10,TCF3,PAWR,BLM,WRNIP1,RPA2,IRF4,NABP2,H2AFY,SS18L1,ORC3,CREB1,CITED2,STAT3,MSH6,GINS1,TELO2,NASP,KAT2A,PRKDC,HELB,POLR3GL,MEN1,RPA1,CBX3,UPF1,POLE,PML,E2F1,HMGB2,CENPT,TERF1,PURA,IPO4,DDB1 |
| 1.667e-12 | -27.12 | regulation of cell cycle phase transition | biological process | GO:1901987 | 456 | 127 | 17256 | 2622 |
ZNF207,FGFR1OP,UBE2E2,GPR132,KMT2E,DYNLL1,TPX2,CUL1,SIRT2,CCNB1,PRKACA,APP,FANCI,CDKN2C,PSMA6,PCNA,PSMD1,BABAM2,MDM2,NEK6,KIF14,CDKN1B,ECD,CDC25B,CEP63,CTDSP2,CARM1,DCTN1,PLK1,PLK3,BRD4,RBX1,PSMA8,BTG2,TAOK1,CUL3,PSMB7,MRNIP,CDC6,AURKB,BRCA1,CDC23,ANLN,SOX4,PSMB9,PAF1,RAD51C,RPS27A,RBL1,PSMD8,PSMD3,NSMCE2,E2F4,XRCC3,CHEK2,VPS4A,TFDP2,GEN1,PSMC1,CSNK1D,TUBB,MAPRE1,CLSPN,PHB2,MECP2,CDT1,CENPF,BABAM1,DCTN2,CDK2AP2,HAUS4,BLM,PSMD9,PAGR1,CNOT11,RAB11A,HAUS2,CDC73,MAD2L2,CNOT3,DDRGK1,RFWD3,RPA2,TFAP4,DTL,PSMD2,RB1,CCP110,PTEN,CENPJ,FBXO7,GTSE1,H2AFY,BRD7,BCL2,FBXL7,KNTC1,CNOT6L,TGFB1,PPP1R9B,ADAM17,PRKDC,PSMA1,MEN1,PRMT2,PSMB3,HAUS8,PSMC4,CNOT9,PCM1,ODF2,TFDP1,CDCA5,E2F1,PML,FAM83D,SSNA1,CNOT6,PKD2,NDE1,ZNF830,CDK2,UBE2C,ESPL1,ANAPC4,CDKN2A,DDB1 |
| 1.753e-12 | -27.07 | GSE28726_ACT_CD4_TCELL_VS_ACT_VA24NEG_NKTCELL_UP | MSigDB lists | GSE28726_ACT_CD4_TCELL_VS_ACT_VA24NEG_NKTCELL_UP | 191 | 68 | 17377 | 2626 |
SRM,RHOG,EXOC3,IMMT,TXN,NUP188,URB2,SLC29A1,OAT,SNAPC4,PA2G4,ZNF75D,PSMD1,UTP18,MTA1,MRPS27,ZNF200,PDCD2,TRA2B,SPTSSA,METTL1,COPS8,MAPRE2,MKLN1,POLR2G,AATF,HMGN4,PPT1,PGGT1B,IDH3A,CPOX,SLC16A7,HNRNPF,ATXN1,SLC25A5,TXNL4A,PPP2CA,TIMM17A,HPS5,SSRP1,DDX42,MIF,SCAMP3,SRGN,ADO,NKRF,NCKAP1,HDDC2,CFLAR,RPA2,SUB1,CPSF4,LPCAT1,MTX2,MAPKAPK3,ACSL3,LDHA,CAPZA2,PSMB3,UTP20,HSPBP1,LTBP4,CCDC86,ELMO1,PARG,NFIL3,DBI,ZBTB24 |
| 1.753e-12 | -27.07 | GSE39556_CD8A_DC_VS_NK_CELL_MOUSE_3H_POST_POLYIC_INJ_UP | MSigDB lists | GSE39556_CD8A_DC_VS_NK_CELL_MOUSE_3H_POST_POLYIC_INJ_UP | 191 | 68 | 17377 | 2626 |
TMEM106C,FGFR1OP,TXN,FOXM1,LAGE3,TPX2,C5orf30,KIF2C,SLC29A1,CCNB1,FANCI,OIP5,FANCL,CDKN2C,CCNA2,DPYSL2,KIF14,POP7,XRCC2,EFCAB11,AKR1B1,KIF22,RNASEH2A,RFC3,RAD51AP1,SLBP,RRM2,NUP155,CDC6,BRCA1,PKMYT1,ICMT,CCNF,PRPSAP1,CHAF1A,PRIM1,HSPB11,H2AFX,KPNA2,ANP32E,CHEK2,DBF4,RRM1,KIF23,BLM,SPAG5,NUP205,EBP,SMC3,CLIC4,GTSE1,TIMELESS,KNTC1,SMC4,GINS1,TK1,PRIM2,NET1,GBA,CAMSAP1,KIF11,MTHFD2,CDC27,POLE,PRPS2,CCNB2,CDK2,ESPL1 |
| 1.811e-12 | -27.04 | mitotic metaphase plate congression | biological process | GO:0007080 | 46 | 28 | 17256 | 2622 |
CHMP2A,PSRC1,PDCD6IP,CDT1,CDCA8,CUL3,NUF2,KIF2C,CCNB1,CHMP2B,CDC23,SPDL1,BECN1,RAB11A,MIS12,KIFC1,KIF18A,CHMP4A,KIF14,CEP55,CDCA5,NUP62,KIF22,CHMP4B,VPS4A,RRS1,CHMP7,SEH1L |
| 1.882e-12 | -27.00 | GSE45365_WT_VS_IFNAR_KO_CD8A_DC_UP | MSigDB lists | GSE45365_WT_VS_IFNAR_KO_CD8A_DC_UP | 183 | 66 | 17377 | 2626 |
RMND5A,KIAA0100,MRPL42,CXXC1,MAGED1,BABAM1,NKRF,HAUS4,CHKB,CDIPT,HCFC1R1,PRKACA,MAPK14,RCOR3,WRB,APP,CCDC28A,HDDC2,PCYOX1L,SLC25A36,GSTK1,CEP104,ADD3,LRRC8D,ATIC,MRPL34,TIMELESS,SEPT11,ANP32A,RPN2,CORO1A,ACAD8,GPD1L,DNMT1,SLC35A1,MTX2,LDHB,PGAP2,TDP1,TRAPPC9,PIGT,POLR2G,FRAT2,MRPL16,ESYT1,GALNT7,SLC25A5,SERP1,SF3A2,CLNS1A,AMZ2,CAT,ZNF862,WAS,MID1IP1,PPP2R5A,TMED10,MPV17,ACAT1,AP1S1,MDH1,ACTB,ACADM,AP2S1,USP13,S100PBP |
| 1.939e-12 | -26.97 | MODULE_152 | MSigDB lists | MODULE_152 | 109 | 47 | 17377 | 2626 |
COX5B,NDUFA5,NDUFV2,TOMM20,SUCLG1,NDUFA4,GLUD1,COX4I1,CYCS,ATP6V1B2,SDHA,NDUFS4,DECR1,ATP6V0B,NDUFV1,NDUFA2,GOT2,NDUFS8,CYC1,NDUFA3,ATP6V0D1,ATP6V1G1,GPX4,ATP2C1,MRPL12,LACTB,ATP6V0A1,NDUFA7,VDAC1,NDUFB1,SLC25A5,ABCF1,ECH1,SDHB,ATP6V1D,MTHFD2,PRDX5,COX8A,COX5A,UQCRH,ATP6V0C,NDUFS5,IDH3B,CLN3,ATP6V0E1,MRPL3,GCSH |
| 1.939e-12 | -26.97 | MORF_TERF2IP | MSigDB lists | MORF_TERF2IP | 109 | 47 | 17377 | 2626 |
UBE2D3,UBN1,PRKCSH,RAF1,SUMO2,NACA,TOR1AIP1,AGPAT1,BECN1,PARN,RAB11A,SRRT,SLC25A36,TERF2IP,TFAP4,CYHR1,DNAJC8,FBXO7,NAP1L4,CPSF4,MORC3,KDM3B,SNRNP200,SEC61B,AATF,KRAS,NFATC2IP,SEPT7,PRKRA,RAB1A,EIF4H,POLR2A,MFN2,PPP2CA,SMAD2,RPS27A,STK38,HNRNPH3,COX7A2L,ATXN2L,ROCK1,COPS6,B4GALT3,CSNK1D,DDB1,NUDT3,SMNDC1 |
| 1.972e-12 | -26.95 | regulation of primary metabolic process | biological process | GO:0080090 | 6175 | 1097 | 17256 | 2622 |
ZBTB10,TSC2,HEXB,CCNL2,RBM4,ZNF275,FBXO22,EEF2K,CDKN2C,USF1,THAP4,RAD23B,DNM2,CRY2,ECD,TIPARP,BAK1,ERCC1,ZNF559,GABPA,EHMT1,HNRNPF,WDHD1,MIER2,ARF4,BOLA3,AHNAK,MID1IP1,SMAD2,RPS27A,OGT,RNASEL,SMAD1,ZNF75A,OAZ1,PDCD4,SLC25A33,ZNF720,HIVEP3,CLSPN,GGA1,DHX9,EIF2AK4,PSMD9,PARN,CDC73,TFAP4,CD59,SMC3,MEGF8,FBXO7,MYDGF,CPSF4,MVP,NUP85,PABPC1,PHKG2,NSUN4,PPP6R1,IFRD1,AGGF1,RBM42,FOXK1,MAPKAPK3,MTA2,GTPBP4,ITM2A,BCLAF1,ELK1,EIF4H,FNTA,KPNA1,PDLIM1,ETS2,ZNF830,NUP58,ALS2,RHOG,KARS,GGNBP2,NQO1,PTTG1,TPX2,INO80E,DAZAP2,RCOR3,AHCTF1,ZNF420,MTA1,GMEB1,NSFL1C,ZNF226,GPD1L,ZC3H3,RPRD1B,CGGBP1,PDCL3,CPNE1,POLR2L,EID1,KAT7,RPL38,CIRBP,E2F3,POLR2D,HTATIP2,PFKFB3,MEF2D,RAB1A,PPP2CA,CORO1C,PPP5C,USP13,COMMD10,ZNF445,SRSF6,ZFP91,HABP4,FLOT1,ABHD14B,WDR5,PMVK,NEXMIF,PPP1R3B,GOLM1,RPA2,ZBTB45,PSMD2,PDCD10,ZNF260,LTN1,ZNF710,GTF2H2,MED22,PICALM,SH3BP5,GPS2,PARG,ACOX1,CD81,PARP10,YWHAH,THAP5,AAMDC,FAM129A,TRIM11,RBM8A,ENSA,NENF,SND1,FANCI,PAPOLA,ZER1,PRNP,CREM,TET3,NUP210,GLIS2,IL6ST,NOC2L,EIF5,MTPN,RYBP,PLK1,CELSR2,RBX1,RAD51AP1,ZBED5,CDC6,UBE2V1,PBRM1,EAF2,ODC1,USP21,CHD3,ZNF367,E2F4,ADAM9,KPNA2,DVL1,CLN3,BEND6,FAM208A,POT1,ZNF564,FUBP1,PHB2,DNAJB2,CENPF,NKD2,LAMTOR3,CHCHD2,CDK13,DNAJB1,CNOT11,ARID1B,SUB1,MLX,MBD2,SSBP3,ZNF746,ARL6IP1,CTR9,RBM3,ICE2,GLE1,ACSL3,LDB1,MAP4K3,ZNF761,RBM38,IRF5,RXRB,MBIP,ORMDL2,NLRC5,RUVBL2,BCCIP,USP7,TRAF7,ARID2,ZNF416,LYN,PCBP1,BCAP31,ZNF121,VAV1,NRF1,PSMA6,ZNF473,KMT5C,ZNF302,PIN1,PPME1,TARDBP,AHCYL1,STRAP,SPIDR,CTDSP2,ZNF583,PRPF19,SNX25,PPIF,KDM3B,BIRC3,POLR2G,ZNF780B,RAB7A,PPIE,NUP155,EIF3H,IDE,RBL1,UBXN2B,FASTK,STK38,UHRF2,H3F3A,SMAD4,PARD3,BCL2L12,SLC30A9,UNK,MTERF1,AGO2,GTF3A,HMGN3,CDK11B,PAGR1,FZD6,RBM15B,YTHDC1,RHOA,RPRD1A,HMGN5,BTAF1,PRKDC,PCGF1,TRIM26,PDCD6,NEK1,L3MBTL3,BBX,E2F1,RBPJ,TAF12,NR2F2,PGAM1,HIPK3,IFI16,TXN,NUP188,MAX,H2AFZ,TSC22D3,CXXC1,UBE2I,MYEF2,PARK7,GLMP,PA2G4,NOL11,FIZ1,ZNF200,TRA2B,TAF5L,SMARCE1,ZNF800,CDC5L,SRSF10,ZNF524,KLF10,LACTB,SUPT20H,USP22,CBFB,RFC2,EIF3A,ZMYM3,DOT1L,IWS1,MAP3K4,HHEX,MKNK1,BRD2,RPS14,BTF3,SLF1,CCDC59,NMD3,PTOV1,EWSR1,POLR2K,GADD45G,VAV2,PRKAA1,CYCS,SUPT7L,ZNF79,ZNF518A,PSEN1,VPS25,YY1AP1,CNOT3,WDR48,LHX8,EXOSC7,PPP4R1,MSH2,DAPK1,PIK3IP1,TNRC18,FDFT1,SOCS5,EIF5A,ELL2,USF3,ZNF574,EXOSC9,ARID1A,ADRB2,C9orf40,FXR1,PTTG1IP,MAP2K2,CCT8,PHF6,XRCC5,DERL1,CAT,PFDN5,HSPBP1,GOLGA2,EPOP,RBMX,MED15,PIAS2,CEBPG,FAM83D,SAMD8,CABIN1,CDKN2A,ZNF511,NDC1,ATXN3,RAF1,SPINDOC,CCNA2,MTMR4,RALB,LPIN2,ADCY9,SOCS6,MRPS27,CDK12,SAP30,ANKLE2,BRD4,CDC123,DRAP1,ELP4,EDF1,PKMYT1,ERC1,SERP1,TRIM28,SUPT16H,EIF3K,ZNF282,HINT1,CERS6,SAFB,ATF6,BEND3,EYA2,DEPDC1,MECP2,ARGLU1,SECISBP2,POFUT1,HMG20A,WWP2,CCNK,ELP5,PTPN11,AXIN2,FEM1B,CARF,CITED2,MSH6,KAT2A,LONRF3,RFXANK,COMMD4,KLF6,FADD,CBX3,LTBP4,ZHX1,OAZ2,PPP1R11,DDX5,WDR91,TAF6,PURA,DDB1,FAM83G,RORB,ZBED3,CCNC,ZNF76,KMT2E,PTP4A3,COMMD5,ZNF696,JAZF1,TCEA1,CARM1,SRPK2,DEAF1,NCK1,VHL,RIOX2,SREK1,KMT2C,ASF1B,EIF4ENIF1,BRWD1,CAB39,BAZ1B,ZNF268,STK11,CHEK2,CLU,UBE2D3,PPP1R2,PPP1R12A,GORASP1,NACA,UBXN1,PM20D2,THRAP3,RGS2,TTF1,NUP205,LYAR,DTL,MED10,MCPH1,ATP5IF1,CREG1,ERLIN1,RPL6,GBA,EIF2A,SLTM,DAPK3,MASTL,KLHL15,NFIL3,SIAH2,YWHAZ,CTSA,EHD4,SNRNP70,TOB1,N4BP2L2,ADNP2,TCF12,SMARCA4,ORC1,MXD1,USP5,HNRNPA2B1,SAP130,RRN3,UBXN2A,NVL,KIF14,EXOSC1,UTP4,ZNF770,CHP1,POU2AF1,UBQLN4,RNF25,SMU1,PCGF6,ATXN1,GLO1,EDEM2,TOLLIP,MBD3,RPS9,PDHX,HNRNPR,STAT6,ARNTL,MAPK1,BRD9,ABCA1,NAT14,DNAJC2,TRIP12,ZNF316,RAE1,SCYL1,NUP54,PAWR,MXD4,DCUN1D4,FASTKD3,FGFR3,KMT5A,DUS2,NABP2,H2AFY,ARHGEF2,ANP32A,ATG13,LDLRAD3,STAT3,TGFB1,ELOVL5,COA3,PHF20L1,PPP1R9B,DCAF6,PSPC1,HELB,MIER1,RFFL,RCOR1,PRMT2,CDK11A,TFEB,LEMD2,MTMR3,UPF1,KMT2B,CENPT,ZMIZ1,HRAS,SLF2,TERF1,FGFR1OP,MAP3K7CL,KDM4A,XIAP,EDRF1,PPP1R16B,PABPC4,CDK5,CALM2,CIPC,PSMD1,NSRP1,SRSF4,FNIP2,NUP153,SENP1,MLST8,PLK3,ZNF672,AATF,TOPORS,DCUN1D5,STOML2,BRMS1,ZNF689,AXIN1,LIMK1,PRDX5,VIPAS39,MLYCD,TRIM52,TFDP2,E2F2,LONP2,AAAS,SSRP1,PHF23,EZH1,DDRGK1,MCTS1,PHF14,ZNF326,FOXN2,CYFIP1,ETV3,RB1CC1,ZMYND11,MYBL2,SRSF5,CBFA2T2,CSK,DUSP3,SETD3,CNOT6,RNF139,SGF29,EGLN1,ZNF207,PPP1R37,ZNF296,SARNP,TRERF1,IVNS1ABP,UBR2,WDTC1,MYH9,CREBL2,ZNF267,SAFB2,PRKACA,TCF19,APP,ANKIB1,SP100,ZKSCAN1,DDA1,NUP107,MAVS,RNF19A,CLN6,RBM15,ATF2,RNF169,ADCY7,SHOC2,PSRC1,MAP4K4,RNPS1,WBP2,CDCA2,DNAJA1,TAZ,DDX17,CHCHD3,TAF2,HIPK2,RPLP1,TICAM1,FUS,ZBTB11,LRP8,ZNF786,RPS2,TRAK1,JMJD6,GMCL1,AKT1S1,ETS1,ZNF92,SUV39H2,PPP1R8,PRDM4,DCP1A,PDPK1,PPP3CA,TNFAIP3,ZNF512,JTB,ZP3,PDE3B,ZNF862,ZNF180,KEAP1,PITX1,PML,LRPPRC,HMGB2,PSAP,RGL1,USF2,IGBP1,FAF1,THOC1,AGRN,GPBP1L1,PPP1R15B,CSNK2A1,S1PR2,BIRC2,LIN9,PCNA,ZNF639,ETV6,PIK3R2,MYBL1,CCAR1,PTPRK,CDC37,SP3,EXOSC6,BAZ2A,PBXIP1,MRPL12,GMFB,EZR,LRP5,BRCA1,TONSL,SOCS4,ZNF45,LZTR1,CTCF,PPP3CB,RLF,CRLF3,ASXL2,LRRC14,RB1,MED8,TIGAR,TIMELESS,AFF1,MDFIC,MAML1,PREB,TRAPPC9,UTP15,RTF1,EIF2AK1,KRAS,NFATC2IP,EIF4G2,ZNF174,PSMC4,SYNCRIP,TBPL1,PRMT7,RNF114,CYLD,FOXM1,DYNLL1,SUMO2,GGPS1,DUSP22,COMMD8,RPL11,RAD23A,CSDE1,PDK2,ZBTB21,MDM2,TNFAIP8,PDCD2,SAP30L,DVL2,TIMP2,PSMA8,BTG2,NFATC2,KDM1B,USP36,SRSF1,DNAJC10,ATP1A1,CLK3,SCAP,ZNF700,TIMM17A,PSMD3,MAFK,DNAJC17,PLGRKT,ZNF436,NCOA1,ZNF146,CTDP1,MIF4GD,DAP,CDT1,ARID5A,NKRF,CSNK1A1,TFRC,WRNIP1,PTPN2,IRF4,SLC35B4,SS18L1,PTGES3,ZNF202,ZMYM5,BIRC5,TWSG1,TFE3,CDCA7L,GLG1,PKD2,ACADM,UBE2C,ZNF496,YTHDF3,CCNB1,EIF1B,COMMD6,RIC1,PARPBP,CDC25B,MAST2,PLCL2,DNMT1,SEH1L,AKT2,PBK,ELOA,MRNIP,DDX20,AURKB,TMED10,PSMD8,TRAF5,ARRB2,ZNF598,HDAC2,SVIP,DDX58,PPIB,HSPH1,GMFG,CHTF18,NOTCH2,PMF1,METTL3,JMY,NDUFS4,CFLAR,FKBP1A,MEX3C,KLF16,HDAC7,LPCAT1,GNAI2,EEF1D,TERF2,PHF10,ZNF84,CYFIP2,KDM3A,PSMB3,FAS,EPRS,SERTAD2,ZNF777,NSF,ZFP92,QARS,PPP3R1,TCOF1,PPP6R3,MAP3K5,YY1,CDK2,RNF14,ZC3HAV1,DNMT3A,RWDD1,ZBTB37,CAST,SUZ12,RPS6KA1,EIF3D,RAC1,MAGED1,PAIP2,TERF2IP,CRKL,APLP2,ZNF75D,KDM2A,SHC1,UCHL5,CDKN1B,CCT2,RFC3,ERF,TAOK1,CUL3,H2AFV,PSMB9,CENPU,SOCS7,PRDM11,VEZF1,PPP2R5A,STAT1,H2AFX,TRIM32,ATMIN,CSNK1D,RHEBL1,POLQ,POU3F2,NCOR2,TCF3,BABAM1,MYNN,BLM,FOXO3,MAD2L2,GTF2F1,RBM17,PTEN,CREB1,MAP3K14,CNOT6L,NCOA2,TSHZ1,ZFP64,NEK7,WDR18,PARP4,ILF3,TBRG4,MARK2,POLR2A,PRDX1,GNA12,HGS,PRDX3,TFDP1,KHSRP,BRWD3,CPEB2,IER2,NOP2,HNRNPAB,NF1,UBN1,DNAJC24,ZNF107,SIRT2,TAF6L,UBQLN2,MAPK14,SNAPC4,CYREN,RAP1A,EIF4A3,METTL14,PHTF1,SRI,ZBTB22,OGG1,ARID4A,TRIM14,ELOF1,COPS8,TRIM8,RRM2,SOX4,ABHD5,UBTF,GEMIN5,PAF1,PQBP1,ROCK1,RPS26,PSMC1,ZNF768,CIB1,TIA1,MED13L,MEF2A,EPHX2,SRRT,RHBDD1,APOPT1,NFATC3,ZNF449,BUD31,ZNF335,YBX1,BCL2,ACAD8,HP1BP3,ZNF189,VOPP1,CIC,OXR1,PSMA1,ISG15,CAND1,TSC1,RBM25,NSMF,NUP62,ZFP90,RBBP4,HNRNPDL,SMARCD1,ZBTB24,MBD1,ASH1L,MPHOSPH8,IFI27L1,PLAGL2,NSD3,IRF3,CHD1,PAIP1,MEAF6,BABAM2,AKAP8,PARL,CHTOP,F2R,ABI1,HTRA2,MOSPD1,RLIM,FAM172A,ZNF500,PSMB7,NLN,BOLA1,ERBIN,PEF1,BTBD1,ZNF317,TAB2,TULP3,GADD45B,SCARB1,AKNA,SMURF1,PPP2R2D,CBX4,MIF,EYA1,DBF4,KLF13,FBXO5,TANK,PELO,BRD7,SAMD4B,TELO2,HMGN1,ADAM17,PRKAR1B,WDR81,MEN1,ZNF407,SYMPK,SNRPA,HSPA1B,MAPK3,CNOT9,PLAA,ATAD2,OSBPL8,ZRANB2,SRSF3 |
| 2.015e-12 | -26.93 | ILF2 (interleukin enhancer binding factor 2) | protein interactions | 3608 | 290 | 95 | 17029 | 2761 |
COX15,CYLD,NOP2,KMT2E,IVNS1ABP,SUZ12,SF3B1,LAGE3,CUL1,NENF,SND1,BRIX1,BIRC2,PARK7,PAIP1,PABPC4,RPL11,RPL23A,MRPL50,STRBP,EIF4A3,NVL,WDR44,NOC2L,RPF2,TRA2B,TARDBP,FTSJ3,CDC5L,SRP72,CUL3,SREK1,BRCA1,PRKRA,MCM2,VDAC1,FKBP3,TIMM13,DDOST,MRPL55,HNRNPR,NIP7,IARS2,H2AFX,RPS26,CCDC59,MIF4GD,RPS2,EWSR1,CDC40,LAMTOR3,MRPS26,DHX9,RPL15,LMNA,LYAR,RPA2,HUWE1,RPL17,MCM5,ZNF746,RTCB,YBX1,DDX31,RPL19,RBM3,ALDH18A1,MRPL21,ORC3,SPTAN1,YTHDC1,STAU1,DDX28,PRKDC,RPL6,GTPBP4,ILF3,RPL8,RPS24,SRSF5,ABCF1,MATR3,MTR,SF3A2,RHOB,ZFR,RPA1,XRCC5,CAND1,UPF1,SYNCRIP,SNAP23,RUVBL2,SRSF3,CDK2 |
| 2.111e-12 | -26.88 | IVNS1ABP (influenza virus NS1A binding protein) | protein interactions | 10625 | 83 | 41 | 17029 | 2761 |
CYLD,HNRNPAB,IVNS1ABP,ANK3,DHX9,MYH9,THRAP3,PABPC4,SMC3,KLHL20,DAPK1,TRA2B,YBX1,ZNRD1,STAT3,LUC7L2,HNRNPM,NIPSNAP1,PLK1,STAU1,VHL,HNRNPF,ILF3,RPL6,MCM2,PRPSAP1,CDK11A,CENPU,POLR2A,DDX17,UPF1,SYNCRIP,HNRNPR,CHD3,RBMX,LRPPRC,ACTB,USP11,ATP6V1C1,SMURF1,ZC3HAV1 |
| 2.136e-12 | -26.87 | RPS14 (ribosomal protein S14) | protein interactions | 6208 | 232 | 81 | 17029 | 2761 |
NOP9,CYLD,RPLP2,HNRNPUL2,YTHDC2,CUL1,GGPS1,ZNF121,APP,RPL11,RPL23A,KRR1,MDM2,NOC2L,RPF2,CRY2,TARDBP,CDK12,RLIM,RPL35,VHL,RPL38,CUL3,BRCA1,BUD13,MCM2,RPS9,RPSA,DHX57,NSA2,SMAD2,SEC61A1,RPLP1,FUS,COPS6,RRS1,SMURF1,PDCD11,RPS26,DCAF5,CCDC59,TMEM33,CCDC137,PRPF4B,RPS15,RPS2,CCZ1,DHX9,RPL15,BLM,TTF1,NDUFS4,KRI1,HUWE1,RPL17,AHSA1,DDX31,RPL19,FBL,FRMD8,HNRNPM,HP1BP3,STAU1,DDX24,RBM42,ILF3,GTPBP4,RPL8,ZNF574,RPL6,RPS10,RPS24,BMS1,RPL27A,CAND1,RPL36,RPL32,CDK2,CD81,MRPL3,ZBTB24 |
| 2.142e-12 | -26.87 | SART1 (SART1, U4/U6.U5 tri-snRNP-associated protein 1) | protein interactions | 9092 | 117 | 51 | 17029 | 2761 |
SART1,CYLD,CHERP,FOXM1,KMT2E,SUZ12,SF3B1,RAE1,DHX9,USP39,THRAP3,SNRPD3,UBE2I,APP,PABPC4,SUB1,EIF4A3,SRSF4,EFTUD2,MSH2,KIFAP3,TARDBP,PABPC1,PRPF19,CDC5L,SRPK2,SRSF11,STAU1,SNRNP200,ZCCHC10,RBM42,SF3B6,CUL3,ILF3,CRNKL1,PRPF3,SRSF5,MPG,PATL1,SF3A2,SRSF1,DDX23,RBM25,HNRNPR,MFAP1,LUC7L3,PRPF4,DDX5,SNRPG,IFI16,PRPF4B |
| 2.142e-12 | -26.87 | SCARNA22 (small Cajal body-specific RNA 22) | protein interactions | 677770 | 117 | 51 | 17029 | 2761 |
EWSR1,HNRNPAB,CHERP,SF3B1,MECP2,TOR1AIP1,HNRNPUL2,DHX9,SMARCA4,USP39,TOP2B,ATP5F1B,LMNA,SF3B2,RPN1,STRBP,CD3EAP,DDX31,TARDBP,HNRNPM,HP1BP3,PRPF19,CDC5L,CDKN2AIP,DDX24,AATF,PSPC1,PRKDC,ILF3,EZR,RANGAP1,UTP3,PBRM1,ZFR,XRCC5,DDX17,SYNCRIP,RBM25,HNRNPR,RBMX,TBL3,BAZ1B,KHSRP,DDX5,ACTB,FUS,RUVBL2,RBBP4,PDCD11,GPATCH4,IFI16 |
| 2.217e-12 | -26.84 | GSE26156_DOUBLE_POSITIVE_VS_CD4_SINGLE_POSITIVE_THYMOCYTE_DN | MSigDB lists | GSE26156_DOUBLE_POSITIVE_VS_CD4_SINGLE_POSITIVE_THYMOCYTE_DN | 196 | 69 | 17377 | 2626 |
TMEM106C,SRM,IMMT,TXN,HNRNPAB,TRIP10,DYNLL1,TPX2,EBNA1BP2,SLC29A1,CCNB1,BCAT2,KIFC1,FARSA,PSMA6,SPTSSA,GM2A,PLK1,RFC3,NRAS,POLR2G,HMGN4,HNRNPF,WDHD1,PSMG1,CDC6,NDUFA7,PSMB9,CHAF1A,PRIM1,STT3A,PSMD8,MAP4,H2AFX,PDXK,SNRPG,AP2S1,CENPF,PMVK,MYL6B,MFSD10,SPAG5,RPA2,BDH1,ANXA5,AHCY,MRPL40,NIPSNAP1,LDHA,MYBL2,TOMM40,KIF11,FADD,PRDX1,HMGN2,YIF1A,EPRS,MTHFD2,SEC23IP,LTBP4,CCDC6,PRDX3,DBI,PRPS2,SLC16A1,ASNA1,RUVBL2,CCNB2,UBE2C |
| 2.321e-12 | -26.79 | Post-translational protein modification | REACTOME pathways | R-HSA-597592 | 1034 | 253 | 10287 | 1696 |
TMED7,RAB14,PIGM,NUP188,COPA,PRKCSH,PIGQ,MOGS,UBE2Z,DNAJC24,NANS,USP48,UBE2I,BECN1,SEC16A,BIRC2,RNF103,CALM2,RAB8A,NAPG,PCNA,PSMD1,NUP210,RAB35,RAB4A,RAD23B,JOSD1,NUP153,TFG,SENP1,MGAT5,SEH1L,USP34,SP3,USO1,TMEM115,DPM1,SUMF2,AURKB,SLC17A5,AMDHD2,GALNT7,BRCA1,USP22,MCFD2,ICMT,RAB5B,USP21,RAB22A,RAB2B,ARF4,PAF1,MAN2A2,ALG3,SMAD2,STT3A,TMED10,RPS27A,PSMD8,AXIN1,MIA2,OGT,ACTB,ST3GAL2,GALNT10,SMAD1,ARRB2,NGLY1,PSMC1,AAAS,B4GALT2,DDX58,UBE2D3,PIGN,NSMCE4A,CLSPN,GORASP1,DHPS,UBXN1,RAB23,B4GALT1,TOP2B,TMED3,RAB6A,B4GALT4,ASXL2,PSMD9,COPG2,CDC73,NUP205,WDR48,COPB2,CD59,RPN1,C1GALT1,NUS1,SMC3,UBE2Q2,CCP110,DAD1,HDAC7,PIGG,CTR9,RNF135,ZRANB1,NUP85,PPP6R1,TMED2,KDELR1,PREB,EIF5A,TRAPPC9,PIGT,FOXK1,TSTA3,MAN1B1,PSMA1,USP10,RTF1,SYVN1,ADRB2,LY6E,METTL22,GOSR1,PSMB3,PSMC4,SEC31A,DERL1,GALNT2,UAP1,GOLGA2,NSF,SIAH2,PIAS2,FN3KRP,NUP62,CTSA,NANP,YY1,PPP6R3,RNF139,NUP58,CDKN2A,USP7,NDC1,TOMM20,CYLD,ATXN3,GNPNAT1,RAB11B,DYNLL1,SUMO2,COPE,ANK3,INO80E,STAM,RAD23A,USP5,ANKRD28,PHC2,RAB21,BABAM2,MDM2,PSMA6,CCNA2,SP100,ABRAXAS2,UCHL5,MTA1,NUP107,PPP6C,RPN2,MAVS,LMAN1,DCTN1,BIRC3,PSMA8,RAB7A,PSMB7,VDAC2,NUP155,KDM1B,RAB1A,VDAC1,EDEM2,PSMB9,IDE,DDOST,RAB24,PSMD3,NSMCE2,CAMKMT,SEL1L,USP11,B4GALT3,XRCC4,SMAD4,CBX4,CSNK1D,DYNC1LI2,USP13,OTUD5,CMAS,RPS2,B4GALT5,RAE1,BABAM1,GNE,DCTN2,CDCA8,NUP54,SMC6,SUMF1,ARF1,BLM,RAB11A,MAN1A1,MAT2B,PSMD2,PTEN,ARF5,SEC24C,FUT8,AXIN2,ST8SIA2,SLC35A1,RNF5,SPTAN1,TGFB1,MLEC,CNTN5,RHOA,TNFAIP3,KAT2A,PRKDC,USP42,COG1,RANGAP1,OTUD3,RHOT1,ARSK,NEU1,RPA1,RAB18,HGS,KEAP1,SEC23IP,MAGT1,BIRC5,PML,USP20,MBD6,UBE2C |
| 2.324e-12 | -26.79 | ENK_UV_RESPONSE_KERATINOCYTE_UP | MSigDB lists | ENK_UV_RESPONSE_KERATINOCYTE_UP | 514 | 138 | 17377 | 2626 |
POLA2,CCNC,ZNF76,IER2,NOP2,PIGQ,SND1,FKBP2,UBQLN2,EIF1B,MAP1LC3B,RBM4,RNF103,SSR1,CDK5,AKR1B1,TECR,EIF5,CDC37,ERCC1,SNRPB,STX16,RFC2,ODC1,STK17B,STOML2,BRD2,PSMD8,ATP6V0C,ST3GAL2,BTF3,OAZ1,ATP6V0E1,PTOV1,UBE2D3,COX5B,RPS15,PHB2,HLA-E,DNAJB2,UBXN1,CIB1,PCSK7,TMED3,PSMD9,RPN1,VASP,BANF1,BUD31,YBX1,CYC1,PHKG2,IFRD1,POLR2I,ELL2,AMD1,RPS10,LY6E,MPG,PSMB3,IRF5,ISG15,MAGED2,GNAS,PFDN5,ETS2,ERGIC3,CEBPG,YWHAZ,TOB1,CHMP2A,COPE,RAC1,PCBP1,GNB2,MXD1,MOAP1,ATP6V0B,TALDO1,CGGBP1,CFL1,PRPF19,GPX4,DCTN1,PPIF,RPL29,RPL35,POLR2L,SELPLG,DRAP1,PSMB7,ATP6V0A1,MEF2D,DNAJA1,PRPF3,RAB1A,RPS9,TRIM28,EIF3G,EIF3K,TIMM17A,GADD45B,H2AFX,FAU,EYA2,AP2S1,CSNK1D,MIF,SCAMP3,RAE1,CDK2AP2,PMVK,HLA-A,RPL19,NDUFS8,TAGLN2,CITED2,UBE2M,YTHDC1,TGFB1,CSRP1,TNFAIP3,GUK1,RPL8,JTB,TUFM,EMP3,API5,ECH1,POLR2A,NEU1,NUCB1,KPNA4,GPS2,ACOX1,TFE3,PPP1R11,IDH3B |
| 2.366e-12 | -26.77 | mitotic sister chromatid segregation | biological process | GO:0000070 | 109 | 47 | 17256 | 2622 |
ZNF207,CHMP2A,PDCD6IP,PHF23,CDT1,CDCA8,KIF23,RACGAP1,NUF2,KIF2C,CCNB1,SPDL1,BECN1,NCAPG,RAB11A,SPAG5,MIS12,KIFC1,RB1,KIF14,AKAP8,PRC1,NAA50,PDS5B,KIF22,SEH1L,SMC4,PLK1,PSRC1,CUL3,NUSAP1,AURKB,SMC2,CDC23,CHMP2B,KIF18A,CHMP4A,DSN1,KIF18B,CDCA5,CEP55,NUP62,CHMP4B,VPS4A,RRS1,CHMP7,ESPL1 |
| 2.416e-12 | -26.75 | GSE15930_NAIVE_VS_48H_IN_VITRO_STIM_IFNAB_CD8_TCELL_DN | MSigDB lists | GSE15930_NAIVE_VS_48H_IN_VITRO_STIM_IFNAB_CD8_TCELL_DN | 188 | 67 | 17377 | 2626 |
CCNC,PMS2,TMEM97,USP39,POLR3K,PABPC4,FARSA,IARS,RAD23B,PDCD2,KIF22,TARDBP,LMAN1,PDIA6,NAA35,RPRD1B,ARL5A,ELOF1,CLCN3,LARS,MRPL12,PSMG1,RRM2,CDC6,SMC2,PITPNB,NUTF2,MAT2A,STOML2,CDCA4,TIMM13,LUC7L3,U2SURP,OGT,MRPL13,PSMC1,FUBP1,MRPS2,HDDC2,EBP,RPN1,IRF4,EXOSC7,GART,RNFT1,EFTUD2,MDFIC,MRPL11,CPSF4,ALDH18A1,UBE2M,TIMM8B,HMGN5,TSPAN31,SSR2,TBRG4,TOMM40,ABCF1,TARS,SNRPA,MTHFD2,DCK,DBI,SSNA1,RUVBL2,NDUFS5,GCSH |
| 2.437e-12 | -26.74 | GINESTIER_BREAST_CANCER_ZNF217_AMPLIFIED_DN | MSigDB lists | GINESTIER_BREAST_CANCER_ZNF217_AMPLIFIED_DN | 301 | 93 | 17377 | 2626 |
CCDC93,AGRN,KDM4A,URB2,ABCC10,MOGS,SMARCA4,CNTROB,SAFB2,SNAPC4,ZNF473,SH3BP1,INTS1,TRMU,PPP1R12C,TNPO2,TARDBP,ARHGAP17,ZNF524,NOL8,RNPS1,MEF2D,DCLRE1C,MBD3,GFER,USP21,RHEB,GIGYF1,TMEM201,DOT1L,GRIPAP1,PPM1G,PQBP1,ATXN2L,BAZ1B,TICAM1,STK11,SMG9,DMWD,ZNF598,ANKRD13D,GGA1,ZNF316,TCF3,ACAP1,B4GALT1,EPN1,MYO9B,SLC12A9,SUPT7L,SRRT,CNOT3,LMNA,RTKN,MCTS1,FKBP1A,RNF121,KLF16,HDAC7,TNPO3,ARHGEF2,GTSE1,COPS7B,TTC17,FBXL19,NSUN4,PHKG2,RBM15B,AMPD2,CSNK1G2,PRRC2A,CIC,DCAF8,ZNF202,SUGP2,ILF3,RANGAP1,SYMPK,MARK2,MAP2K2,SPPL2B,HAUS8,LEMD2,TTC13,TYW5,ZC3H7B,KHSRP,NUP62,TCOF1,PPP6R2,SNRNP70,C7orf26,SMARCD1 |
| 2.539e-12 | -26.70 | KRIGE_RESPONSE_TO_TOSEDOSTAT_6HR_UP | MSigDB lists | KRIGE_RESPONSE_TO_TOSEDOSTAT_6HR_UP | 836 | 201 | 17377 | 2626 |
HECA,UBE2E2,DCAF15,TSC22D3,FAM129A,TAP1,XIAP,PTP4A3,ABCB10,SLC29A1,AGFG1,NHLRC3,MAP1LC3B,RBM4,ZNF696,SLC25A37,ASPHD2,PRNP,ZER1,DLG5,PA2G4,C18orf32,NOC2L,EIF5,OGG1,ARID4A,SEH1L,TIMM50,ABCC5,MLST8,USP34,SP3,USO1,RHOBTB3,TRIM8,EXOSC6,KLF10,MCL1,STX16,RAB2B,TRIM4,RPL37,MID1IP1,PTER,WDR4,OGT,PTPDC1,DCAF5,PDCD4,NUMB,WSB2,HLA-E,TATDN3,MEF2A,TMED3,B4GALT4,RGS2,APH1B,ZNF518A,RHBDD1,GNS,CD59,KLHL5,SLC38A5,ABHD2,IFRD1,TRAFD1,DHX29,TSPAN31,GTPBP4,UTP15,ITM2A,RIT1,TOMM40,ARMC8,ZNF174,TWISTNB,FAS,OSBPL11,MTHFD2,GALNT2,GOLGA2,NFIL3,RUVBL2,RUFY3,NDE1,N4BP2L2,SMARCD1,USP7,TCF12,CYLD,NQO1,IVNS1ABP,CAST,PLAGL2,CREBL2,CHKB,GGPS1,RPAIN,MXD1,CD320,FARSA,SP100,CCDC50,UTP18,LPIN2,EFCAB11,FAM76B,RBM15,CLN6,FAM3A,GCC1,SCYL3,POC5,SAP30,NXT1,ATXN1,MTMR6,NLN,GORAB,AZI2,TXNL4A,TAZ,DNAJC10,JAK1,HIPK2,PPA2,FTSJ1,ZNF436,SEL1L,NCLN,SCARB1,CENPBD1,AKNA,MAPK1,PDCD11,SMURF1,PDCD2L,CBX4,RAD51D,OTUD5,PKP4,GNE,VPS45,FLOT1,BRAP,LETMD1,SLC12A9,CSNK1A1,ETS1,PMVK,POFUT1,SCYL2,HLA-A,PNO1,DNAJB9,SLC25A36,CAPN2,HOMER1,CLIC4,CTSS,SLC1A4,TANK,DDX31,FBL,ERI3,SGCB,RPL22L1,MYO5A,SAMD4B,NASP,HMGN5,DENND1B,ZMYM5,ILF3,RANGAP1,RAB3IP,PNPLA8,HAGH,ARL17A,BSDC1,SH3GLB1,UTP20,ZNF862,NEK1,ZNF330,TFE3,CTBS,LRPPRC,PML,CCDC69,ACAT1,KHSRP,PKD2,MBD6,RPS6KC1,CPEB2,BYSL,SSSCA1,ESYT2,ZSWIM6 |
| 2.586e-12 | -26.68 | MORF_DAP | MSigDB lists | MORF_DAP | 78 | 38 | 17377 | 2626 |
KARS,NDUFS1,DAP,RAC1,COPE,DCTN2,ENSA,UBE4A,AP3S1,PSMD9,SDHA,BCAP31,SF3B2,CALM2,SEC24C,RAD23B,HADHB,NDUFS8,TECR,MAML1,SLC35A1,TMED2,KDELR1,GPX4,NSDHL,WBP2,TRIM28,ARF4,PDCD6,DDOST,PRDX3,PSMD8,PPM1G,MPV17,KPNA2,MDH1,AP2S1,PTOV1 |
| 2.595e-12 | -26.68 | MORF_CDC10 | MSigDB lists | MORF_CDC10 | 140 | 55 | 17377 | 2626 |
IMMT,NUP188,ADD1,SUMO2,NACA,STARD7,LANCL1,XPO7,TERF2IP,CRKL,HNRNPA2B1,TFAP4,RPA2,DNAJC8,DUT,PIN1,CAPZA1,TXLNA,CS,AFF1,TCEA1,NAP1L4,MORC3,SRSF11,KDM3B,SHOC2,SNRNP200,AATF,TACC1,PRKDC,SUGP2,RNPS1,PSMA1,KRAS,BMS1,SEPT7,MCFD2,PRKRA,SERP1,CDK11A,POLR2A,XRCC5,NSA2,PPP2CA,HNRNPR,HNRNPH3,TIMM17A,SAFB,ATXN2L,LRPPRC,TCOF1,CDK2,TERF1,SMNDC1,DDB1 |
| 2.725e-12 | -26.63 | GSE14415_INDUCED_TREG_VS_TCONV_UP | MSigDB lists | GSE14415_INDUCED_TREG_VS_TCONV_UP | 172 | 63 | 17377 | 2626 |
PTMS,MCM10,RPS6KA1,CHTF18,TKT,CDCA3,CDCA8,NUF2,UBE2I,STMN1,PCBP1,POLR3K,TUBGCP2,SPAG5,FBXO5,CALM2,CDKN2C,CCNA2,DUT,TTC9C,CS,GLTP,KIF22,TAGLN2,CDC25B,IMPA2,GINS1,PLK1,RFC3,PIGT,PRIM2,CDC123,RAD51AP1,PBK,KIF15,MKI67,PSMA1,CKAP2L,RRM2,AURKB,MTX1,LY6E,DDX39A,SNRPA,ASF1B,PRIM1,DDOST,SURF4,KIF18B,BIRC5,DCK,NEIL3,PSMD3,DBI,NRM,TFDP1,ASNA1,SCARB1,TAF12,GEN1,CCNB2,FAM72A,POLQ |
| 2.727e-12 | -26.63 | GO_NCRNA_PROCESSING | MSigDB lists | GO_NCRNA_PROCESSING | 352 | 104 | 17377 | 2626 |
SART1,KARS,DDX47,TP53RK,NOP2,RPLP2,LAGE3,EBNA1BP2,C2orf49,RPL11,RPL23A,KRR1,HNRNPA2B1,PA2G4,NOL11,DUS4L,EIF4A3,UTP18,INTS1,GRSF1,TRMU,POP7,UBA5,EXOSC1,INTS12,RPF2,FTSJ3,RPP25,METTL1,RPL29,RPL35,EXOSC6,NOL8,NSUN2,METTL2A,RPL38,UTP3,PRKRA,GAR1,MAK16,RPS9,RPSA,NSA2,RPL37,SMAD2,DUS3L,DGCR8,LSM6,RPS27A,RPS14,TBL3,WDR4,RPLP1,FTSJ1,RNASEL,RRS1,FAU,OSGEPL1,SMAD1,PDCD11,RPS26,CSNK1D,INTS2,CTU2,RPS15,RPS2,TRMT6,RPL15,METTL3,SRRT,PNO1,RRP36,GTPBP3,DDX56,EXOSC7,INTS7,RPL17,RPL19,GEMIN4,FBL,ERI3,CPSF4,NSUN4,TEX10,WDR18,TYW1,RPS10,RPL6,UTP15,RPL8,RPS24,EXOSC9,BMS1,RPL27A,TSR2,RPL36,UTP20,RPL32,TYW5,TSEN15,CDKN2A,BYSL,TYW1B,DDX52 |
| 2.767e-12 | -26.61 | GO_NEGATIVE_REGULATION_OF_CELL_CYCLE_PROCESS | MSigDB lists | GO_NEGATIVE_REGULATION_OF_CELL_CYCLE_PROCESS | 201 | 70 | 17377 | 2626 |
ZNF207,CHMP2A,GPR132,THOC1,CAST,PTTG1,CSNK2A1,SMARCA4,CCNB1,FANCI,MDM2,PCNA,CCNA2,CDKN1B,CTDSP2,CARM1,CDC5L,PRPF19,PLK3,PLK1,BRD4,BTG2,AURKB,BRCA1,SOX4,CCNF,RPS27A,E2F4,ZNF268,VPS4A,CHEK2,TFDP2,MIF,CLSPN,CENPF,BLM,CDC73,CNOT3,MAD2L2,FBXO5,RPA2,TFAP4,RFWD3,CCNK,RB1,SMC3,PTEN,CENPJ,FBXO7,MSH2,BRD7,H2AFY,GTSE1,BCL2,CNOT6L,TERF2,HMGN5,PRKDC,MEN1,PRMT2,RBM38,TFDP1,E2F1,PML,CNOT6,PKD2,ZNF830,CDK2,ESPL1,TERF1 |
| 2.891e-12 | -26.57 | SYNCRIP (synaptotagmin binding cytoplasmic RNA interacting protein) | protein interactions | 10492 | 313 | 100 | 17029 | 2761 |
CYLD,TXN,HNRNPAB,NOP2,IVNS1ABP,PTTG1,CUL1,EBNA1BP2,IKBIP,APP,PAIP1,RPL23A,PHC2,CSDE1,MRPL50,IARS,MTA1,TARDBP,TIMM50,CUL3,MKI67,BRCA1,UTP3,PRKRA,MCM2,TXNL4A,LUC7L,GAR1,FKBP3,DHX15,RPSA,RCC1L,SRSF1,STOML2,DOT1L,DDX17,MAP3K4,HNRNPR,RPS27A,NSMCE2,CEP55,H2AFX,COX5A,FUS,COPS6,SMURF1,ZNF598,CCDC59,C2CD5,CAPN1,DDX42,CCDC137,USP13,RECQL,NDUFV2,RRP15,HABP4,SDC2,MED13L,PCSK7,RACGAP1,WWP2,RPA2,RPN1,PSMD2,KLF16,INTS7,MCM5,ZNF746,PTPN11,YBX1,ICE2,PABPC1,HNRNPM,LUC7L2,STAU1,DDX24,ILF3,UHRF1BP1,PNPLA8,MACF1,EIF4H,SF3A2,RPA1,CAND1,LEMD2,EPRS,UPF1,SNAP23,USP32,DUSP11,DDX5,ZRANB2,SRSF3,SNRNP70,WDR91,CDK2,HEXA,CD81,IPO4 |
| 2.952e-12 | -26.55 | MORF_PPP2CA | MSigDB lists | MORF_PPP2CA | 125 | 51 | 17377 | 2626 |
ZNF207,KARS,MRPL9,NUP188,HNRNPAB,UBN1,RAF1,SUMO2,NACA,STARD7,CUL1,XPO7,UBE2I,AP3S1,BECN1,TERF2IP,HNRNPA2B1,DNAJC8,PIN1,CAPZA1,HADHB,CS,TARDBP,TCEA1,NAP1L4,HNRNPM,MORC3,CCT2,IFRD1,SNRNP200,SEC61B,AATF,RNPS1,GMFB,PSMB7,PSMA1,SEPT7,SLC25A5,DDX39A,EIF4H,POLR2A,PPP2CA,RPS27A,SAFB,RBMX,HNRNPH3,LRPPRC,MDH1,IDH3B,HDAC2,SMNDC1 |
| 3.198e-12 | -26.47 | GSE23114_WT_VS_SLE2C1_MOUSE_SPLEEN_B1A_BCELL_UP | MSigDB lists | GSE23114_WT_VS_SLE2C1_MOUSE_SPLEEN_B1A_BCELL_UP | 189 | 67 | 17377 | 2626 |
RHOG,CHMP2A,CYTIP,IMMT,FEZ2,HNRNPAB,URB2,DYNLL1,PLAGL2,EBNA1BP2,ZNF267,FKBP2,MRPL19,PRKD3,PSMD1,UTP18,TXLNA,RPN2,SLC26A2,AHCYL1,COPS8,SP3,ANKLE2,MKLN1,HMGN4,GABPA,EZR,UTP3,MAK16,RAB22A,PPP2CA,DHX16,HPS5,SNRPG,RRS1,WSB2,CDS2,SRGN,CYCS,PSMD9,PRPF18,PNO1,CFLAR,SUB1,IRF4,ATP6V0A2,SS18L1,MAP3K14,LPCAT1,ADAM17,MLEC,WDR1,EIF4G2,TARS,FADD,PRDX1,CAND1,MTHFD2,UAP1,LTBP4,SYNCRIP,PRDX3,NFIL3,CD81,PGAM1,RNF14,TERF1 |
| 3.330e-12 | -26.43 | GSE21927_GMCSF_IL6_VS_GMCSF_GCSF_TREATED_BONE_MARROW_DN | MSigDB lists | GSE21927_GMCSF_IL6_VS_GMCSF_GCSF_TREATED_BONE_MARROW_DN | 185 | 66 | 17377 | 2626 |
ZNF207,H2AFZ,NDUFB6,URB2,RAC1,CSNK2A1,SLC25A44,RAD23A,KIFC1,FANCL,NOL11,NVL,GOT2,DNAAF2,GRSF1,RAD23B,PPP6C,MRPL34,JOSD1,APOOL,MCMBP,CDC5L,PRPF19,CSTF1,CPOX,GMFB,SMC2,PITPNB,CDC23,MRPS14,PRIM1,KIF18B,HNRNPR,PQBP1,ATF6,PDXK,MIF,DBF4,SMC6,HDDC2,DDRGK1,RFWD3,BUD31,YBX1,CYC1,IFT46,NUDC,SMC4,PPAN,MOB4,NASP,GTPBP4,USP10,RANGAP1,EIF4G2,ABCF1,ISG15,NCDN,MFN2,SLC19A1,KIF18A,ATAD2,NFIL3,COX8A,ACAT1,FAF1 |
| 3.379e-12 | -26.41 | V$YY1_Q6 | MSigDB lists | V$YY1_Q6 | 223 | 75 | 17377 | 2626 |
IER2,ASH1L,PRKCSH,PPP1R15B,WDR13,ENSA,GIT2,TMEM69,USF1,TBC1D14,FIZ1,CNPY4,TRA2B,ZBTB22,TARDBP,CHTOP,RNF26,EIF5,SCYL3,RPRD1B,ZNF524,TRIM8,ATP13A1,MIOS,SLC26A6,KIF15,RAB22A,MAP3K4,DAP3,CAMKMT,UQCRH,BTF3,ZC3HC1,PRPF38B,NACA,ADO,STRN4,TIA1,MYNN,ARF1,PMF1,CSNK1A1,FOXO3,CNOT3,CCNK,RPN1,ZNF335,YBX1,RBM3,LYPLA2,RBM15B,B3GALT6,RPRD1A,NASP,TOP3A,UBE4B,SEPT7,ARMC8,NDRG3,NCDN,POLR2A,ECH1,DDX23,RXRB,TSC1,OSBPL11,CCDC6,SETD3,HNRNPH3,SLC25A19,WIPI2,PREPL,YY1,TAF6,N4BP2L2 |
| 3.392e-12 | -26.41 | PRPF8 (pre-mRNA processing factor 8) | protein interactions | 10594 | 174 | 66 | 17029 | 2761 |
SART1,NOP2,FOXM1,SUZ12,SF3B1,USP39,SND1,SNRPD3,UBE2I,PCBP1,SF3B2,EIF4A3,PIN1,ECD,SRPK2,PRPF19,CDC5L,SNRNP200,SNRPB,CRNKL1,SMU1,RNPS1,CUL3,PRPF3,DHX15,SUPT16H,HNRNPR,RPS14,PRPF4,SNRPG,ABCA1,PRPF4B,C9orf78,CDC40,NACA,TCF3,DHX9,PIP4K2A,RPA2,MEX3C,HUWE1,MCM5,EFTUD2,ZNF746,PABPC1,HNRNPM,LUC7L2,STAU1,ZMYND11,PRKDC,SF3B6,PIP4K2C,RPL6,RANGAP1,SEPT7,SF3A2,PHF6,DDX23,RPA1,SCARB2,C1orf131,KPNA4,ISY1-RAB43,RUVBL2,ZNF830,SNRNP70 |
| 3.557e-12 | -26.36 | regulation of macromolecule biosynthetic process | biological process | GO:0010556 | 4262 | 790 | 17256 | 2622 |
ZBTB10,KDM4A,HEXB,XIAP,CCNL2,EDRF1,RBM4,ZNF275,CDK5,USF1,PSMD1,CIPC,THAP4,DNM2,CRY2,FNIP2,ECD,SENP1,PLK3,ZNF672,ZNF559,AATF,GABPA,EHMT1,WDHD1,MIER2,TOPORS,ARF4,STOML2,BRMS1,BOLA3,SMAD2,RPS27A,ZNF689,AXIN1,PRDX5,OGT,VIPAS39,RNASEL,TRIM52,TFDP2,SMAD1,E2F2,ZNF75A,PDCD4,ZNF720,SSRP1,HIVEP3,DHX9,EZH1,EIF2AK4,PSMD9,PARN,CDC73,MCTS1,DDRGK1,TFAP4,SMC3,MEGF8,PHF14,ZNF326,FOXN2,MYDGF,PABPC1,NUP85,NSUN4,CYFIP1,IFRD1,ETV3,FOXK1,RB1CC1,ZMYND11,MTA2,GTPBP4,MYBL2,ITM2A,BCLAF1,CBFA2T2,ELK1,EIF4H,PDLIM1,ETS2,SETD3,CNOT6,ZNF830,SGF29,RNF139,EGLN1,ZNF207,RHOG,ZNF296,KARS,SARNP,TRERF1,IVNS1ABP,UBR2,PTTG1,WDTC1,CREBL2,ZNF267,INO80E,SAFB2,RCOR3,TCF19,APP,AHCTF1,ZNF420,SP100,ZKSCAN1,MTA1,GMEB1,NUP107,ZNF226,ANKRD13C,MAVS,ATF2,RBM15,ZC3H3,RPRD1B,CGGBP1,CPNE1,PSRC1,POLR2L,EID1,KAT7,WBP2,RPL38,POLR2D,CIRBP,E2F3,HTATIP2,MEF2D,DDX17,TAF2,PPP2CA,CHCHD3,HIPK2,TICAM1,FUS,ZBTB11,LRP8,USP13,COMMD10,ZNF786,ZNF445,ZFP91,HABP4,TRAK1,JMJD6,GMCL1,ABHD14B,WDR5,ETS1,NEXMIF,ZNF92,PPP1R3B,ZBTB45,PSMD2,SUV39H2,PPP1R8,PRDM4,ZNF260,LTN1,ZNF710,GTF2H2,MED22,PDPK1,PPP3CA,TNFAIP3,ZNF512,ZP3,PICALM,ZNF862,ZNF180,KEAP1,GPS2,PITX1,LRPPRC,PML,HMGB2,CD81,PARP10,IGBP1,USF2,YWHAH,THAP5,FAF1,AGRN,THOC1,AAMDC,GPBP1L1,TRIM11,PPP1R15B,FAM129A,RBM8A,CSNK2A1,SND1,BIRC2,CREM,PRNP,LIN9,TET3,PCNA,GLIS2,ZNF639,ETV6,PIK3R2,NOC2L,EIF5,MYBL1,MTPN,CCAR1,RYBP,PTPRK,PLK1,SP3,CELSR2,RBX1,PBXIP1,BAZ2A,ZBED5,MRPL12,EZR,CDC6,UBE2V1,LRP5,PBRM1,EAF2,BRCA1,USP21,TONSL,CHD3,ZNF367,E2F4,DVL1,ZNF45,BEND6,FAM208A,POT1,ZNF564,FUBP1,LZTR1,PHB2,CENPF,CTCF,CHCHD2,CDK13,DNAJB1,PPP3CB,RLF,ASXL2,CNOT11,CRLF3,ARID1B,LRRC14,SUB1,RB1,MLX,MED8,MBD2,SSBP3,ZNF746,CTR9,TIMELESS,MDFIC,AFF1,RBM3,ICE2,GLE1,MAML1,PREB,TRAPPC9,LDB1,UTP15,KRAS,EIF2AK1,RTF1,ZNF761,NFATC2IP,EIF4G2,IRF5,ZNF174,PSMC4,RXRB,SYNCRIP,ORMDL2,NLRC5,TBPL1,PRMT7,RUVBL2,USP7,CYLD,TRAF7,ARID2,FOXM1,DYNLL1,ZNF416,DUSP22,PCBP1,COMMD8,ZNF121,VAV1,CSDE1,ZBTB21,NRF1,PSMA6,ZNF473,MDM2,KMT5C,ZNF302,PIN1,TARDBP,STRAP,SAP30L,ZNF583,DVL2,KDM3B,POLR2G,ZNF780B,PSMA8,BTG2,PPIE,NFATC2,KDM1B,EIF3H,SCAP,ZNF700,RBL1,MAFK,PSMD3,ZNF436,UHRF2,DNAJC17,NCOA1,H3F3A,SMAD4,ZNF146,BCL2L12,SLC30A9,CTDP1,UNK,MIF4GD,MTERF1,DAP,CDT1,AGO2,ARID5A,GTF3A,HMGN3,NKRF,CDK11B,PAGR1,FZD6,WRNIP1,PTPN2,IRF4,SS18L1,PTGES3,RBM15B,RPRD1A,RHOA,HMGN5,BTAF1,PRKDC,ZNF202,ZMYM5,PCGF1,TRIM26,BIRC5,TWSG1,L3MBTL3,TFE3,CDCA7L,BBX,E2F1,PKD2,RBPJ,TAF12,NR2F2,HIPK3,IFI16,TXN,ZNF496,MAX,H2AFZ,TSC22D3,CXXC1,YTHDF3,UBE2I,EIF1B,COMMD6,MYEF2,PARK7,GLMP,PA2G4,NOL11,FIZ1,ZNF200,TAF5L,MAST2,SMARCE1,DNMT1,ZNF800,CDC5L,SRSF10,ZNF524,KLF10,AKT2,ELOA,DDX20,SUPT20H,AURKB,USP22,RFC2,CBFB,ZMYM3,IWS1,DOT1L,MAP3K4,HHEX,MKNK1,BRD2,PSMD8,RPS14,BTF3,ARRB2,TRAF5,ZNF598,CCDC59,NMD3,HDAC2,PTOV1,SVIP,DDX58,HSPH1,EWSR1,POLR2K,CHTF18,PRKAA1,NOTCH2,PMF1,SUPT7L,ZNF79,PSEN1,ZNF518A,METTL3,VPS25,YY1AP1,CNOT3,JMY,CFLAR,LHX8,MEX3C,KLF16,HDAC7,DAPK1,TNRC18,EEF1D,TERF2,EIF5A,PHF10,ZNF84,ELL2,ZNF574,USF3,EXOSC9,ARID1A,ADRB2,C9orf40,CYFIP2,FXR1,KDM3A,MAP2K2,CCT8,PSMB3,PHF6,XRCC5,CAT,PFDN5,EPRS,ZNF777,SERTAD2,GOLGA2,EPOP,ZFP92,RBMX,QARS,MED15,CEBPG,PPP3R1,PIAS2,SAMD8,TCOF1,YY1,MAP3K5,RNF14,CDK2,CDKN2A,ZNF511,DNMT3A,ATXN3,RWDD1,ZBTB37,RPS6KA1,RAF1,SUZ12,EIF3D,RAC1,MAGED1,PAIP2,TERF2IP,SPINDOC,CCNA2,ZNF75D,SHC1,KDM2A,UCHL5,LPIN2,MRPS27,CDKN1B,CDK12,SAP30,CCT2,BRD4,RFC3,ERF,CDC123,DRAP1,CUL3,ELP4,EDF1,H2AFV,PSMB9,ERC1,TRIM28,SERP1,CENPU,PRDM11,SUPT16H,EIF3K,VEZF1,ZNF282,HINT1,CERS6,SAFB,STAT1,H2AFX,ATF6,TRIM32,BEND3,EYA2,ATMIN,RHEBL1,POU3F2,NCOR2,DEPDC1,MECP2,TCF3,ARGLU1,SECISBP2,MYNN,BLM,POFUT1,FOXO3,HMG20A,MAD2L2,WWP2,GTF2F1,CCNK,PTEN,ELP5,CARF,CITED2,CREB1,CNOT6L,NCOA2,TSHZ1,ZFP64,KAT2A,NEK7,WDR18,ILF3,PARP4,RFXANK,KLF6,COMMD4,FADD,POLR2A,CBX3,PRDX3,ZHX1,TFDP1,KHSRP,DDX5,BRWD3,TAF6,CPEB2,PURA,FAM83G,RORB,ZBED3,CCNC,ZNF76,IER2,NOP2,HNRNPAB,UBN1,KMT2E,DNAJC24,PTP4A3,ZNF107,SIRT2,TAF6L,COMMD5,MAPK14,SNAPC4,ZNF696,EIF4A3,JAZF1,METTL14,PHTF1,SRI,ZBTB22,TCEA1,OGG1,ARID4A,CARM1,TRIM14,ELOF1,DEAF1,TRIM8,NCK1,VHL,RIOX2,RRM2,SOX4,KMT2C,ASF1B,GEMIN5,UBTF,PAF1,EIF4ENIF1,BRWD1,PQBP1,BAZ1B,ZNF268,CHEK2,CLU,PSMC1,UBE2D3,PPP1R12A,ZNF768,NACA,CIB1,MED13L,TIA1,MEF2A,THRAP3,RGS2,TTF1,SRRT,LYAR,NFATC3,ZNF449,MED10,BUD31,ZNF335,BCL2,YBX1,ACAD8,MCPH1,ZNF189,HP1BP3,VOPP1,CREG1,ERLIN1,CIC,RPL6,GBA,PSMA1,EIF2A,SLTM,DAPK3,CAND1,TSC1,NFIL3,SIAH2,NUP62,ZFP90,RBBP4,HNRNPDL,TOB1,N4BP2L2,SMARCD1,ADNP2,ZBTB24,TCF12,MBD1,ASH1L,MPHOSPH8,SMARCA4,PLAGL2,NSD3,IRF3,ORC1,CHD1,MXD1,PAIP1,MEAF6,HNRNPA2B1,SAP130,RRN3,NVL,AKAP8,CHTOP,F2R,UTP4,ZNF770,RLIM,CHP1,MOSPD1,POU2AF1,FAM172A,ZNF500,PGGT1B,RNF25,PCGF6,PSMB7,ATXN1,BOLA1,GLO1,ERBIN,MBD3,RPS9,ZNF317,TAB2,HNRNPR,STAT6,TULP3,ARNTL,AKNA,SMURF1,MAPK1,BRD9,CBX4,NAT14,DNAJC2,ZNF316,EYA1,SCYL1,DBF4,KLF13,PAWR,MXD4,FBXO5,FASTKD3,KMT5A,PELO,NABP2,H2AFY,ANP32A,BRD7,ARHGEF2,STAT3,TGFB1,SAMD4B,PHF20L1,COA3,DCAF6,HMGN1,PSPC1,MIER1,RCOR1,PRMT2,MEN1,ZNF407,CDK11A,MAPK3,TFEB,HSPA1B,CNOT9,LEMD2,UPF1,ATAD2,KMT2B,ZRANB2,CENPT,ZMIZ1,HRAS,TERF1 |
| 3.686e-12 | -26.33 | regulation of macromolecule metabolic process | biological process | GO:0060255 | 6354 | 1123 | 17256 | 2622 |
ZBTB10,TSC2,HEXB,CCNL2,RBM4,ZNF275,FBXO22,EEF2K,RPL23A,CDKN2C,USF1,THAP4,RAD23B,DNM2,CRY2,ECD,ZNRD1,TIPARP,BAK1,ERCC1,ZNF559,GABPA,EHMT1,HNRNPF,WDHD1,MIER2,ARF4,BOLA3,AHNAK,SMAD2,RPS27A,OGT,RNASEL,SMAD1,ZNF75A,OAZ1,PDCD4,ZNF720,HIVEP3,CLSPN,GGA1,DHX9,EIF2AK4,PSMD9,PARN,CDC73,TFAP4,CD59,SMC3,MEGF8,FBXO7,MYDGF,CPSF4,MVP,NUP85,PABPC1,PHKG2,NSUN4,PPP6R1,IFRD1,AGGF1,RBM42,FOXK1,MAPKAPK3,MTA2,GTPBP4,ITM2A,BCLAF1,ELK1,EIF4H,FNTA,KPNA1,PDLIM1,ETS2,ZNF830,NUP58,ALS2,RHOG,KARS,GGNBP2,PTTG1,ANK3,TPX2,INO80E,DAZAP2,RCOR3,AHCTF1,ZNF420,MTA1,GMEB1,NSFL1C,ZNF226,GPD1L,ZC3H3,RPRD1B,CGGBP1,PDCL3,CPNE1,POLR2L,EID1,KAT7,RPL38,CIRBP,E2F3,POLR2D,HTATIP2,MEF2D,RAB1A,PPP2CA,LSM6,CORO1C,PPP5C,USP13,COMMD10,ZNF445,SRSF6,ZFP91,HABP4,FLOT1,ABHD14B,WDR5,NEXMIF,TUT4,PPP1R3B,RPA2,ZBTB45,PSMD2,PDCD10,ITGB8,ZNF260,LTN1,ZNF710,GTF2H2,MED22,PICALM,SH3BP5,GPS2,PARG,CD81,PARP10,YWHAH,THAP5,AAMDC,FAM129A,TRIM11,RBM8A,ENSA,NENF,SND1,FANCI,PAPOLA,ZER1,PRNP,CREM,TET3,NUP210,GLIS2,IL6ST,NOC2L,EIF5,MTPN,RYBP,PLK1,CELSR2,RBX1,RAD51AP1,ZBED5,CDC6,UBE2V1,PBRM1,EAF2,ODC1,USP21,CHD3,ZNF367,E2F4,ADAM9,KPNA2,DVL1,CLN3,BEND6,FAM208A,POT1,ZNF564,FUBP1,PHB2,DNAJB2,CENPF,NKD2,LAMTOR3,CHCHD2,CDK13,DNAJB1,CNOT11,ARID1B,SUB1,MLX,MBD2,SSBP3,ZNF746,ARL6IP1,CTR9,RBM3,ICE2,GLE1,LDB1,MAP4K3,ZNF761,RBM38,IRF5,RXRB,RPL36,MBIP,ORMDL2,NLRC5,RUVBL2,BCCIP,USP7,TRAF7,RPLP2,ARID2,ZNF416,LYN,PCBP1,BCAP31,ZNF121,VAV1,NRF1,PSMA6,ZNF473,KMT5C,ZNF302,PIN1,PPME1,TARDBP,AHCYL1,STRAP,SPIDR,CTDSP2,ZNF583,PRPF19,SNX25,KDM3B,BIRC3,POLR2G,ZNF780B,RAB7A,PPIE,NUP155,EIF3H,IDE,RBL1,UBXN2B,FASTK,STK38,UHRF2,H3F3A,SMAD4,PARD3,BCL2L12,SLC30A9,UNK,MTERF1,AGO2,GTF3A,HMGN3,ARF1,CDK11B,PAGR1,SCYL2,FZD6,POLR1B,RBM15B,YTHDC1,RHOA,RPRD1A,HMGN5,BTAF1,PRKDC,PCGF1,TRIM26,PDCD6,NEK1,L3MBTL3,BBX,E2F1,RBPJ,TAF12,NR2F2,PGAM1,HIPK3,IFI16,TXN,NUP188,MAX,H2AFZ,TSC22D3,CXXC1,UBE2I,MYEF2,PARK7,GLMP,PA2G4,NOL11,FIZ1,ZNF200,TRA2B,TAF5L,SMARCE1,ZNF800,CDC5L,SRSF10,ZNF524,KLF10,SUPT20H,USP22,CBFB,RFC2,EIF3A,ZMYM3,DOT1L,IWS1,MAP3K4,HHEX,MKNK1,BRD2,RPS14,BTF3,SLF1,CCDC59,NMD3,PTOV1,EWSR1,POLR2K,GADD45G,PRKAA1,GSPT2,CYCS,SUPT7L,ZNF79,ZNF518A,PSEN1,VPS25,YY1AP1,CNOT3,WDR48,LHX8,EXOSC7,PPP4R1,MSH2,DAPK1,TNRC18,SOCS5,EIF5A,ELL2,USF3,ZNF574,RPS24,EXOSC9,ARID1A,ADRB2,C9orf40,FXR1,PTTG1IP,MAP2K2,CCT8,TWISTNB,PHF6,XRCC5,DERL1,CAT,PFDN5,HSPBP1,GOLGA2,EPOP,RBMX,MED15,PIAS2,ARAP1,CEBPG,FAM83D,SAMD8,CABIN1,CDKN2A,ZNF511,NDC1,ATXN3,RAF1,SPINDOC,CCNA2,MTMR4,RALB,LPIN2,ADCY9,SOCS6,MRPS27,CDK12,SAP30,ANKLE2,BRD4,CDC123,DRAP1,ELP4,EDF1,PKMYT1,ERC1,SERP1,TRIM28,SUPT16H,EIF3K,ZNF282,HINT1,DGCR8,CERS6,SAFB,ATF6,BEND3,EYA2,DEPDC1,MECP2,ARGLU1,SECISBP2,POFUT1,HMG20A,WWP2,CCNK,ELP5,FUT8,PTPN11,AXIN2,FEM1B,RPL19,CARF,CITED2,MSH6,KAT2A,LONRF3,RFXANK,KCNQ1,COMMD4,KLF6,FADD,CBX3,RPL32,LTBP4,ZHX1,OAZ2,PPP1R11,DDX5,WDR91,TAF6,PURA,DDB1,FAM83G,RORB,ZBED3,CCNC,ZNF76,KMT2E,PTP4A3,COMMD5,ZNF696,JAZF1,TCEA1,SLC35C2,CARM1,SRPK2,DEAF1,NCK1,VHL,RIOX2,SREK1,KMT2C,ASF1B,RPL37,EIF4ENIF1,BRWD1,CAB39,BAZ1B,ZNF268,STK11,CHEK2,CLU,UBE2D3,PPP1R2,PPP1R12A,GORASP1,UBXN1,NACA,RPL15,PM20D2,THRAP3,RGS2,TTF1,NUP205,PRPF18,LYAR,DTL,MED10,MCPH1,ATP5IF1,POLR2I,CREG1,ERLIN1,RPL6,GBA,EIF2A,SLTM,DAPK3,MASTL,KLHL15,NFIL3,SIAH2,YWHAZ,CTSA,EHD4,SNRNP70,TOB1,N4BP2L2,ADNP2,TCF12,PRKAB1,SMARCA4,ORC1,MXD1,USP5,HNRNPA2B1,SAP130,RRN3,UBXN2A,CD3EAP,NVL,KIF14,EXOSC1,UTP4,ZNF770,CHP1,POU2AF1,UBQLN4,PGGT1B,RNF25,SMU1,PCGF6,ATXN1,GLO1,EDEM2,TOLLIP,MBD3,RPS9,HNRNPR,STAT6,ARNTL,MAPK1,BRD9,NAT14,DNAJC2,TRIP12,ZNF316,RAE1,SCYL1,NUP54,PAWR,MXD4,DCUN1D4,FASTKD3,FGFR3,KMT5A,DUS2,NABP2,H2AFY,ARHGEF2,ANP32A,ATG13,LDLRAD3,STAT3,TGFB1,COA3,PHF20L1,PPP1R9B,DCAF6,PSPC1,HELB,MIER1,RFFL,RCOR1,PRMT2,CDK11A,TFEB,LEMD2,MTMR3,UPF1,ZC3H7B,KMT2B,CENPT,ZMIZ1,HRAS,SLF2,TERF1,FGFR1OP,MAP3K7CL,KDM4A,XIAP,EDRF1,PPP1R16B,PABPC4,CDK5,CALM2,CIPC,PSMD1,NSRP1,SRSF4,FNIP2,NUP153,SENP1,MLST8,PLK3,ZNF672,AATF,TOPORS,DCUN1D5,SLC50A1,STOML2,BRMS1,ZNF689,AXIN1,LIMK1,PRDX5,VIPAS39,SMG9,TRIM52,TFDP2,E2F2,AAAS,SSRP1,PHF23,EZH1,LMNA,DDRGK1,MCTS1,PHF14,ZNF326,FOXN2,CYFIP1,ETV3,RB1CC1,ZMYND11,MYBL2,RPS10,SRSF5,CBFA2T2,MATR3,POLR2J,CSK,DUSP3,SETD3,CNOT6,RNF139,SGF29,EGLN1,ZNF207,PPP1R37,ZNF296,SARNP,TRERF1,IVNS1ABP,UBR2,WDTC1,MYH9,CREBL2,ZNF267,SAFB2,PRKACA,TCF19,APP,ANKIB1,SP100,ZKSCAN1,DDA1,NUP107,ANKRD13C,MAVS,RNF19A,CLN6,RBM15,ATF2,RNF169,ADCY7,SHOC2,PSRC1,MAP4K4,RNPS1,WBP2,CDCA2,DNAJA1,DDX17,CHCHD3,TAF2,NT5C3B,HIPK2,RPLP1,TICAM1,FUS,ZBTB11,LRP8,ZNF786,RPS2,TRAK1,JMJD6,GMCL1,AKT1S1,ETS1,ZNF92,SUV39H2,PPP1R8,PRDM4,DCP1A,PDPK1,PPP3CA,TNFAIP3,ZNF512,JTB,ZP3,DDX39A,ZNF180,ZNF862,KEAP1,PITX1,MAPK6,PML,LRPPRC,HMGB2,PSAP,USF2,IGBP1,FAF1,THOC1,AGRN,GPBP1L1,PPP1R15B,CSNK2A1,S1PR2,BIRC2,LIN9,PCNA,ZNF639,ETV6,PIK3R2,MYBL1,CCAR1,PTPRK,CDC37,SP3,EXOSC6,BAZ2A,PBXIP1,MRPL12,GMFB,EZR,LRP5,BRCA1,PRKRA,OPTN,TONSL,SOCS4,ACTB,ZNF45,LZTR1,CTCF,PPP3CB,RLF,CRLF3,ASXL2,LRRC14,RB1,MED8,TIGAR,TIMELESS,AFF1,MDFIC,MAML1,PREB,TRAPPC9,UTP15,RTF1,EIF2AK1,KRAS,NFATC2IP,EIF4G2,ZNF174,PSMC4,SYNCRIP,TBPL1,PRMT7,RNF114,CYLD,FOXM1,DYNLL1,SUMO2,DUSP22,COMMD8,RPL11,RAD23A,CSDE1,ZBTB21,MDM2,TNFAIP8,PDCD2,SAP30L,DVL2,RPL29,RPL35,TIMP2,PSMA8,BTG2,NFATC2,KDM1B,USP36,RPSA,SRSF1,DNAJC10,CLK3,SCAP,ZNF700,TIMM17A,PSMD3,MAFK,DNAJC17,PLGRKT,ZNF436,NCOA1,ZNF146,CTDP1,MIF4GD,DAP,CDT1,ARID5A,NKRF,CSNK1A1,TFRC,WRNIP1,PTPN2,IRF4,SS18L1,PTGES3,ZNF202,ZMYM5,BIRC5,TWSG1,TFE3,CDCA7L,GLG1,PKD2,UBE2C,ZNF496,YTHDF3,CCNB1,EIF1B,COMMD6,RIC1,PARPBP,CDC25B,MAST2,PLCL2,DNMT1,SEH1L,AKT2,PBK,ELOA,MRNIP,DDX20,AURKB,TMED10,PSMD8,TRAF5,ARRB2,ZNF598,HDAC2,SVIP,DDX58,PPIB,HSPH1,GMFG,CHTF18,NOTCH2,PMF1,METTL3,JMY,NDUFS4,CFLAR,FKBP1A,MEX3C,KLF16,HDAC7,LPCAT1,GNAI2,TMED2,EEF1D,TERF2,PHF10,ZNF84,CYFIP2,KDM3A,PATL1,PSMB3,FAS,EPRS,SERTAD2,ZNF777,NSF,ZFP92,QARS,PPP3R1,TCOF1,MAP3K5,PPP6R3,YY1,CDK2,RNF14,ZC3HAV1,DNMT3A,RWDD1,ZBTB37,CAST,SUZ12,SF3B1,RPS6KA1,EIF3D,RAC1,MAGED1,PAIP2,TERF2IP,CRKL,APLP2,ZNF75D,KDM2A,SHC1,UCHL5,CDKN1B,CCT2,RFC3,ERF,TAOK1,CUL3,H2AFV,PSMB9,CENPU,SOCS7,PRDM11,VEZF1,PPP2R5A,STAT1,H2AFX,TRIM32,ATMIN,CSNK1D,RHEBL1,POLQ,POU3F2,NCOR2,TCF3,BABAM1,MYNN,BLM,FOXO3,MAD2L2,GTF2F1,RBM17,PTEN,RPL17,UPF2,CREB1,MAP3K14,CNOT6L,NCOA2,TSHZ1,ZFP64,NEK7,WDR18,RPL8,PARP4,ILF3,TBRG4,RPL27A,MARK2,POLR2A,PRDX1,GNA12,HGS,PRDX3,TFDP1,KHSRP,BRWD3,CPEB2,IER2,NOP2,HNRNPAB,NF1,UBN1,DNAJC24,ZNF107,SIRT2,TAF6L,UBQLN2,MAPK14,SNAPC4,EDC3,ZNF804A,RAP1A,CYREN,EIF4A3,METTL14,PHTF1,SRI,ZBTB22,OGG1,ARID4A,TRIM14,ELOF1,COPS8,TRIM8,RRM2,SOX4,UBTF,GEMIN5,PAF1,PQBP1,ROCK1,RPS26,PSMC1,RPS15,ZNF768,CIB1,MED13L,TIA1,MEF2A,EPHX2,SRRT,RHBDD1,APOPT1,NFATC3,ZNF449,BUD31,ZNF335,YBX1,BCL2,ACAD8,HP1BP3,ZNF189,VOPP1,CIC,OXR1,PSMA1,ISG15,CAND1,GNAS,TSC1,RBM25,NSMF,NUP62,ZFP90,RBBP4,HNRNPDL,SMARCD1,ZBTB24,MBD1,ASH1L,MPHOSPH8,IFI27L1,PLAGL2,NSD3,IRF3,CHD1,PAIP1,MEAF6,BABAM2,AKAP8,PARL,CHTOP,F2R,ABI1,HTRA2,MOSPD1,RLIM,FAM172A,ZNF500,PSMB7,BOLA1,ERBIN,PEF1,BTBD1,ZNF317,TAB2,TULP3,GADD45B,AKNA,SMURF1,PPP2R2D,CBX4,MIF,EYA1,DBF4,KLF13,FBXO5,TANK,PELO,BRD7,SAMD4B,TELO2,HMGN1,ADAM17,PRKAR1B,MEN1,ZNF407,SYMPK,SNRPA,HSPA1B,MAPK3,CNOT9,PLAA,ATAD2,OSBPL8,ZRANB2,SRSF3 |
| 3.741e-12 | -26.31 | GSE19941_LPS_VS_LPS_AND_IL10_STIM_IL10_KO_MACROPHAGE_UP | MSigDB lists | GSE19941_LPS_VS_LPS_AND_IL10_STIM_IL10_KO_MACROPHAGE_UP | 169 | 62 | 17377 | 2626 |
POLA2,CHTF18,EIF3D,SNX15,CERK,CDCA8,TPX2,KIF23,KIF2C,PCBP1,SPAG5,FBXO5,USP5,SF3B2,CLIC4,TBC1D22A,GTSE1,ANP32A,RPN2,AHDC1,ANAPC7,CDC25B,CREB1,KCNAB2,ELOF1,BAK1,PLK1,EIF3L,TK1,POLR2I,MKI67,SEPT8,ITM2A,SSR2,CKAP2L,LRRC8A,ANAPC2,SOX4,ANLN,MCM2,KIF11,BSDC1,ASF1B,DOT1L,MOSPD3,CAT,ATP1A1,KIF18B,CDCA5,PPM1G,ARNTL,H2AFX,E2F1,ARRDC1,WDR76,TAF12,PPP5C,CDK2,GLCCI1,ESPL1,ZC3HC1,SSRP1 |
| 3.783e-12 | -26.30 | MORF_ERH | MSigDB lists | MORF_ERH | 107 | 46 | 17377 | 2626 |
COX5B,KARS,PHB2,DYNLL1,SUMO2,STARD7,COX4I1,UBE2I,PARK7,ERH,PCNA,NDUFA2,UTP18,BANF1,CYC1,STRAP,CCT2,HMGN1,POLR2I,POLR2G,CDC123,SNRPB,PSMB7,TUFM,RNPS1,JTB,H2AFV,EIF4H,TRIM28,PRDX1,PSMB3,RHEB,CBX3,STOML2,EIF3K,PDCD6,HSPB11,PSMD8,ACLY,UQCRH,YWHAZ,MDH1,SRSF3,SNRPG,YY1,PSMC1 |
| 3.793e-12 | -26.30 | vesicle-mediated transport | biological process | GO:0016192 | 1774 | 372 | 17256 | 2622 |
CCDC93,TMED7,RAB14,TSC2,ADAM10,HEXB,TAP1,AP3M2,TGOLN2,NHLRC3,GYG1,SYNRG,CMTM6,RIC1,CDK5,NAPG,PA2G4,PSMD1,ASAP2,RABGAP1L,AP1M1,DNM2,AP2B1,MARCH2,TFG,KCNAB2,USO1,RHOBTB3,TMEM115,NRAS,ARHGAP45,KIF15,MCFD2,RAB22A,RAB2B,ARF4,WAS,TMED10,RPS27A,LIMK1,MYO18A,ITGB1,VIPAS39,ATP6V0C,ARRB2,RTN3,ANXA11,SVIP,HSPH1,DNAJC5,GMFG,GGA1,CCZ1,VAV2,ACAP1,KIF23,B4GALT1,MAN2B1,TMED3,PSEN1,VPS25,COPG2,COPB2,TMEM179B,GNS,CD59,ARPC5,SNX18,RIMS3,OSTF1,PIKFYVE,MVP,LPCAT1,SYTL3,PPP6R1,TMED2,APOL1,CYFIP1,FTL,GCC2,MAPKAPK3,WDR1,C1orf35,CAPZA2,ADRB2,PKM,CYFIP2,GOSR1,CCT8,RHOB,PI4K2A,XRCC5,MAGED2,CAT,SEC31A,SCARB2,GOLGA2,NSF,CSNK1G1,ERGIC3,ACLY,APPL2,ARAP1,GPI,PPP6R3,NRBP1,ALS2,RHOG,EXOC3,ANKRD27,SYS1,RAB11B,TRIP10,ANK3,ACTR3,RAC1,VTI1A,OLA1,MON1B,MYH9,NIT2,BCL2L1,AP1B1,STAM,CPNE3,REPS1,APP,APLP2,SH3BP1,TBC1D14,BRI3,TAP2,TMBIM1,DCTN1,SNX8,CPNE1,ENPP4,CCT2,GOPC,CUL3,ATP6V0A1,RAB1A,AP4E1,ERC1,KIF2A,ALDH3B1,CHMP4A,DSN1,DDOST,VPS26B,RAB24,CORO1C,PDXK,LRP8,CSNK1D,TUBB,DYNC1LI2,SCAMP3,MANBA,HABP4,TRAK1,JMJD6,RAB11A,HEATR5B,PIP5K1C,PSMD2,HUWE1,ARF5,ANXA5,CNN2,TAGLN2,GTF2H2,SPTAN1,DENND1B,RABIF,HEBP2,MACF1,KIF11,PICALM,SMAP2,YIF1A,KIF18A,HGS,MAGT1,CCZ1B,STX18,FAM3C,LY75,PSAP,WDR91,CD81,VPS29,ESYT2,SNAPIN,ADA2,COPA,KIF2C,AGFG1,CDC42SE2,RUFY1,BECN1,MAPK14,SEC16A,KCMF1,GIT2,PCYOX1L,RAB8A,RAP1A,CDC42,AP3S2,RAB35,DPYSL2,PIK3R2,TXLNA,ZFYVE27,KIF22,RP2,CARMIL1,NCK1,CYSTM1,EZR,LRP5,PITPNB,RAB5B,STX16,OPTN,NECAP2,TBC1D17,AGPAT2,GRIPAP1,MIA2,CAB39,ACTB,VPS4A,ROCK1,CLU,CLN3,C2CD5,CAPN1,STARD3NL,GORASP1,TM9SF4,NKD2,LAMTOR3,ASAH1,KLC1,EPN1,RACGAP1,CDK13,PPP3CB,NCKAP1,RAB6A,RINL,VMP1,CAPZA1,KIFAP3,LRSAM1,CSNK1G3,PREB,KDELR1,CYTH1,TRAPPC9,CREG1,EIF2AK1,ARPC1A,ARMC8,APPL1,CAND1,GOLGA4,SNAP23,EXOC4,CTSA,EHD4,UNC13C,WASF2,CHMP2A,SNX27,CORO7,DYNLL1,COPE,ZFYVE21,LYN,BCAP31,ANKRD28,VAV1,BRPF3,SAR1A,PPP6C,BCAP29,CORO1A,CYB5R1,APOOL,CLTB,LMAN1,PDIA6,ABI1,GM2A,CHP1,ARHGAP17,TIMP2,PPT1,RAB7A,PPIE,PSMB7,WIPF1,BICD2,CHMP2B,TOLLIP,PEF1,SURF4,PSMD3,AP1S1,CANT1,CHMP4B,SCARB1,MAPK1,LTA4H,AP2S1,CHID1,ABCA1,MIF,KIF3B,SMAP1,GOLPH3L,PDAP1,DCTN2,SRGN,SCYL1,VPS45,TMX3,CHIC2,ARF1,GGA2,CSNK1A1,AP3S1,SCYL2,TFRC,FERMT3,KIF5B,CTSS,KLHL20,GRK2,SEC24C,YIF1B,LDLRAD3,MYO5A,MICAL3,TGFB1,CSNK1G2,MLEC,RHOA,FAM49B,SNX2,SCFD2,COG1,WDR81,NEU1,MAPK3,HSPA1B,RAB18,SEC23IP,ATP6V1D,PDCD6,GOLGA7,ELMO1,SNAP29,PGRMC1,IMPDH1,USP20,CHMP7,PGAM1,HRAS |
| 3.851e-12 | -26.28 | SF3B1 (splicing factor 3b subunit 1) | protein interactions | 23451 | 194 | 71 | 17029 | 2761 |
SART1,CYLD,COPA,THOC1,SUZ12,CUL1,CSNK2A1,USP39,SNRPD3,RPL23A,SF3B2,SAP130,MDM2,EIF4A3,TRA2B,TARDBP,RBM15,PRPF19,CDC5L,NOL12,SNRNP200,RNPS1,CUL3,TOPORS,PRPF3,BRCA1,MCM2,DHX15,RPSA,SRSF1,TIMM13,SURF4,HNRNPR,BAZ1B,PRPF4,KPNA2,XRCC3,SNRPG,RRS1,H3F3A,SMAD1,ARRB2,SMURF1,SMNDC1,DDX42,SSRP1,UNK,RPS2,LMNA,RBM17,RPA2,MCM5,PPP1R8,EFTUD2,CAPZA1,ZNF326,HNRNPM,PPAN,MOB4,STAU1,SF3B6,ILF3,SRSF5,SF3A2,SNRPA,CAND1,RPA1,EPRS,KPNA1,RBMX,YWHAZ |
| 3.903e-12 | -26.27 | RPL37A (ribosomal protein L37a) | protein interactions | 6168 | 210 | 75 | 17029 | 2761 |
CYLD,NOP2,RPLP2,CUL1,EBNA1BP2,BRIX1,MYEF2,APP,RPL11,RPL23A,MDM2,EIF4A3,RPF2,AHCYL1,FTSJ3,CDK12,FYTTD1,RPL29,RPL35,EID1,RPL38,CUL3,SREK1,BRCA1,UTP3,BUD13,MCM2,SLC25A5,GAR1,RPS9,RPSA,NSA2,RPL37,RPS27A,NIP7,RPS14,RPLP1,RRS1,RPS26,CCDC137,NIFK,RPS15,RPS2,DHX9,RPL15,TTF1,LYAR,DDX56,SMC3,EIF2S2,RPL17,RBM34,DDX31,RPL19,PABPC1,PPAN,STAU1,DDX24,ZNF512,GTPBP4,ILF3,RPL8,TUFM,RPL6,RPS10,RPS24,RPL27A,KIF11,CAND1,RPL36,NAP1L1,RBM25,RPL32,ZC3HAV1,GPATCH4 |
| 4.017e-12 | -26.24 | amide biosynthetic process | biological process | GO:0043604 | 471 | 129 | 17256 | 2622 |
KARS,CYLD,RPLP2,RWDD1,MRPS15,MRPL39,EIF3D,EFL1,EIF1B,RBM4,MRPL19,PAIP1,PABPC4,EEF2K,RPL23A,RPL11,MRPL50,FARSA,IARS,MRPS27,MRPL34,EIF5,SPTSSA,MRPL32,MRPL57,RPL29,LARS,RPL35,HARS,MRPL43,RPL38,MRPL12,NDUFA7,POLG2,MRPS14,EIF3G,RPS9,EIF3H,RPSA,EIF3A,RPL37,EIF3K,GEMIN5,MRPL2,DAP3,MRPL55,RPS27A,CERS6,RPS14,CHCHD1,MRPL27,EIF2D,PPA2,RPLP1,FTSJ1,IARS2,QRSL1,DHFR2,B4GALT3,MRPL13,RPS26,ZNF598,PDF,GCLM,RPS15,MRPL9,RPS2,MRPL42,MRPS2,DHPS,AGO2,GSPT2,MRPS26,RPL15,SECISBP2,CHAC2,GFM2,MCTS1,EIF2S2,GART,GATC,RPL17,ATIC,EFTUD2,PELO,RRBP1,MRPL54,LTN1,RPL19,MRPL40,MRPL48,MRPL21,MRPL11,ST8SIA2,GTF2H2,RPL22L1,PABPC1,PPA1,EEF1D,CARS2,EIF5A,EIF3L,ATP5IF1,DHX29,NOA1,RPL6,GBA,RPL8,TUFM,RPS10,MRPS10,RPS24,MRPL16,EIF2A,HAGH,EIF4H,EIF4G2,RPL27A,GUF1,ABCF1,TARS,RPL36,EPRS,RPL32,QARS,SAMD8,SMPD4,CPEB2,MRPL3 |
| 4.260e-12 | -26.18 | GO_REGULATION_OF_CHROMOSOME_SEGREGATION | MSigDB lists | GO_REGULATION_OF_CHROMOSOME_SEGREGATION | 79 | 38 | 17377 | 2626 |
ZNF207,GORASP1,CENPF,PTTG1,SMC6,CTCF,CSNK2A1,RACGAP1,KIF2C,SIRT2,CCNB1,BECN1,MAD2L2,SPAG5,FBXO5,RB1,NEK6,CDC42,PTEN,AXIN2,H2AFY,PLK1,CUL3,CDC6,AURKB,RAB1A,CDC23,GOLGA2,RAD18,CDC27,NSMCE2,CDCA5,XRCC3,GEN1,UBE2C,TERF1,ESPL1,ANAPC4 |
| 4.293e-12 | -26.17 | mitotic cell cycle phase transition | biological process | GO:0044772 | 262 | 84 | 17256 | 2622 |
POLA2,FGFR1OP,CHMP2A,MAX,GPR132,FOXM1,DYNLL1,ENSA,CUL1,ORC1,CCNB1,PRKACA,CDKN2C,RAB8A,CCNA2,PCNA,PPME1,PPP6C,DNM2,CDKN1B,CDC25B,CEP63,TACC3,DCTN1,PLK1,PLK3,BRD4,CUL3,RRM2,CDC6,PKMYT1,CDC23,MCM2,OPTN,PRIM1,TAF2,RPS27A,E2F4,ITGB1,CHMP4B,CHEK2,TFDP2,PPP2R2D,CSNK1D,TUBB,CTDP1,MAPRE1,MCM10,PPP1R12A,CDT1,DCTN2,DBF4,HAUS4,CRLF3,HAUS2,FBXO5,RPA2,RB1,CCP110,CENPJ,MCM5,FBXL7,ORC3,CAMK2G,PPP3CA,PRIM2,NASP,BORA,RPA1,MASTL,HAUS8,PCM1,POLE,CDC27,TFDP1,ODF2,E2F1,SSNA1,NDE1,CCNB2,UBE2C,CHMP7,CDK2,CDKN2A |
| 4.316e-12 | -26.17 | NOP56 (NOP56 ribonucleoprotein) | protein interactions | 10528 | 268 | 89 | 17029 | 2761 |
COX15,NOP2,URB2,CSNK2A1,SMARCA4,EBNA1BP2,BRIX1,UBE2I,RBM4,RPL11,RPL23A,KRR1,DECR1,UTP18,NOC2L,TARDBP,UTP4,FTSJ3,RFC3,CIRBP,CUL3,MKI67,RIOX2,CDC6,BRCA1,VDAC1,SLC25A5,RFC2,LSG1,RPS9,DHX15,DHX57,UBTF,NSA2,NIP7,RPS14,TBL3,RRS1,ARRB2,CCDC137,NIFK,RPS2,RRP15,DHX9,RPL15,SCYL2,LMNA,KRI1,LYAR,DDX56,EIF2S2,RPL17,RBM34,PELO,ZNF746,YBX1,RPL19,POLR1B,FBL,HNRNPM,LUC7L2,PPAN,DDX24,PRRC2A,ABCF2,RPL6,GTPBP4,RPL8,ILF3,TUFM,RPS24,USP10,KRAS,EXOSC9,FXR1,RPL27A,KLF6,ABCF1,CAND1,RPL36,LEMD2,UTP20,NAP1L1,KPNA1,CCDC86,RPL32,TCOF1,GPATCH4,ESYT2 |
| 4.409e-12 | -26.15 | GSE43863_TH1_VS_LY6C_INT_CXCR5POS_MEMORY_CD4_TCELL_UP | MSigDB lists | GSE43863_TH1_VS_LY6C_INT_CXCR5POS_MEMORY_CD4_TCELL_UP | 186 | 66 | 17377 | 2626 |
SRM,ZNF207,BCCIP,PLXNC1,TMEM184B,URB2,TAP1,AGFG1,BRIX1,CPNE3,ANKRD28,SNUPN,NOL11,ZNF639,ZNF770,ARL5A,AATF,BIRC3,IDH3A,NSUN2,PCGF6,LUC7L,MAK16,STOML2,TBL3,PSMD8,WDR4,RWDD4,SCARB1,PPP5C,SLC25A33,RHEBL1,PDF,DNAJC2,MRPS2,SRSF6,PDAP1,B4GALT5,TRMT6,WDR5,TMEM165,CFLAR,RBM17,HOMER1,DDX56,ERH,EIF2S2,NUS1,SLC1A4,ATIC,FUT8,NAA50,DDX31,GEMIN4,CPSF4,SLC25A1,RBM15B,TMEM39A,PGS1,ABCF2,WDR18,TWISTNB,CCDC6,SIAH2,SLC16A1,RUVBL2 |
| 4.437e-12 | -26.14 | regulation of nitrogen compound metabolic process | biological process | GO:0051171 | 6020 | 1070 | 17256 | 2622 |
ZBTB10,TSC2,HEXB,CCNL2,RBM4,ZNF275,FBXO22,EEF2K,CDKN2C,USF1,THAP4,RAD23B,DNM2,CRY2,ECD,TIPARP,BAK1,ERCC1,ZNF559,GABPA,EHMT1,HNRNPF,WDHD1,MIER2,ARF4,BOLA3,AHNAK,SMAD2,RPS27A,OGT,RNASEL,SMAD1,ZNF75A,OAZ1,PDCD4,SLC25A33,ZNF720,HIVEP3,CLSPN,GGA1,DHX9,EIF2AK4,PSMD9,PARN,CDC73,CD59,TFAP4,SMC3,MEGF8,FBXO7,MYDGF,CPSF4,MVP,PABPC1,NUP85,NSUN4,PPP6R1,IFRD1,AGGF1,RBM42,FOXK1,MAPKAPK3,MTA2,GTPBP4,ITM2A,BCLAF1,ELK1,EIF4H,FNTA,KPNA1,PDLIM1,ETS2,ZNF830,NUP58,ALS2,RHOG,KARS,GGNBP2,NQO1,PTTG1,TPX2,INO80E,DAZAP2,RCOR3,AHCTF1,ZNF420,MTA1,GMEB1,NSFL1C,ZNF226,GPD1L,ZC3H3,RPRD1B,CGGBP1,PDCL3,CPNE1,POLR2L,EID1,KAT7,RPL38,E2F3,CIRBP,POLR2D,HTATIP2,PFKFB3,MEF2D,RAB1A,PPP2CA,CORO1C,PPP5C,USP13,COMMD10,ZNF445,SRSF6,ZFP91,HABP4,FLOT1,ABHD14B,WDR5,NEXMIF,PPP1R3B,RPA2,ZBTB45,PSMD2,PDCD10,ZNF260,LTN1,ZNF710,GTF2H2,MED22,PICALM,SH3BP5,GPS2,PARG,CD81,PARP10,YWHAH,THAP5,AAMDC,FAM129A,TRIM11,RBM8A,ENSA,NENF,SND1,FANCI,PAPOLA,ZER1,PRNP,CREM,TET3,NUP210,GLIS2,IL6ST,NOC2L,EIF5,MTPN,RYBP,PLK1,CELSR2,RBX1,RAD51AP1,ZBED5,CDC6,UBE2V1,PBRM1,EAF2,ODC1,USP21,CHD3,ZNF367,E2F4,ADAM9,KPNA2,DVL1,CLN3,BEND6,FAM208A,POT1,ZNF564,FUBP1,PHB2,DNAJB2,CENPF,NKD2,LAMTOR3,CHCHD2,CDK13,DNAJB1,CNOT11,ARID1B,SUB1,MLX,MBD2,SSBP3,ZNF746,ARL6IP1,CTR9,RBM3,ICE2,GLE1,ACSL3,LDB1,MAP4K3,ZNF761,RBM38,IRF5,RXRB,MBIP,ORMDL2,NLRC5,RUVBL2,BCCIP,USP7,TRAF7,ARID2,ZNF416,LYN,PCBP1,BCAP31,ZNF121,VAV1,NRF1,PSMA6,ZNF473,KMT5C,ZNF302,PIN1,PPME1,TARDBP,AHCYL1,STRAP,SPIDR,CTDSP2,ZNF583,PRPF19,SNX25,PPIF,KDM3B,BIRC3,POLR2G,ZNF780B,RAB7A,PPIE,NUP155,EIF3H,IDE,RBL1,UBXN2B,FASTK,STK38,UHRF2,H3F3A,SMAD4,PARD3,BCL2L12,SLC30A9,UNK,MTERF1,AGO2,GTF3A,HMGN3,CDK11B,PAGR1,FZD6,RBM15B,YTHDC1,RHOA,RPRD1A,HMGN5,BTAF1,PRKDC,PCGF1,TRIM26,PDCD6,NEK1,L3MBTL3,BBX,E2F1,RBPJ,TAF12,NR2F2,PGAM1,HIPK3,IFI16,TXN,NUP188,MAX,H2AFZ,TSC22D3,CXXC1,UBE2I,MYEF2,PARK7,GLMP,PA2G4,NOL11,FIZ1,ZNF200,TRA2B,TAF5L,SMARCE1,ZNF800,CDC5L,SRSF10,ZNF524,KLF10,SUPT20H,USP22,RFC2,CBFB,EIF3A,ZMYM3,DOT1L,IWS1,MAP3K4,HHEX,MKNK1,BRD2,RPS14,BTF3,SLF1,CCDC59,NMD3,PTOV1,EWSR1,POLR2K,GADD45G,PRKAA1,CYCS,SUPT7L,ZNF79,ZNF518A,PSEN1,VPS25,YY1AP1,CNOT3,WDR48,LHX8,EXOSC7,PPP4R1,MSH2,DAPK1,TNRC18,SOCS5,EIF5A,ELL2,USF3,ZNF574,EXOSC9,ARID1A,ADRB2,C9orf40,FXR1,PTTG1IP,MAP2K2,CCT8,PHF6,XRCC5,DERL1,CAT,PFDN5,HSPBP1,GOLGA2,EPOP,RBMX,MED15,PIAS2,CEBPG,FAM83D,SAMD8,CABIN1,CDKN2A,ZNF511,NDC1,ATXN3,RAF1,SPINDOC,CCNA2,RALB,LPIN2,ADCY9,SOCS6,MRPS27,CDK12,SAP30,ANKLE2,BRD4,CDC123,DRAP1,ELP4,EDF1,PKMYT1,ERC1,SERP1,TRIM28,SUPT16H,EIF3K,ZNF282,HINT1,CERS6,SAFB,ATF6,BEND3,EYA2,DEPDC1,MECP2,ARGLU1,SECISBP2,POFUT1,HMG20A,WWP2,CCNK,ELP5,PTPN11,AXIN2,FEM1B,CARF,CITED2,MSH6,KAT2A,LONRF3,RFXANK,KLF6,COMMD4,FADD,CBX3,LTBP4,ZHX1,OAZ2,PPP1R11,DDX5,WDR91,TAF6,PURA,DDB1,FAM83G,RORB,ZBED3,CCNC,ZNF76,KMT2E,PTP4A3,COMMD5,ZNF696,JAZF1,TCEA1,CARM1,SRPK2,DEAF1,NCK1,VHL,RIOX2,SREK1,KMT2C,ASF1B,EIF4ENIF1,BRWD1,CAB39,BAZ1B,ZNF268,STK11,CHEK2,CLU,UBE2D3,PPP1R2,PPP1R12A,GORASP1,UBXN1,NACA,PM20D2,THRAP3,RGS2,TTF1,NUP205,LYAR,DTL,MED10,MCPH1,ATP5IF1,CREG1,ERLIN1,RPL6,GBA,EIF2A,SLTM,DAPK3,MASTL,KLHL15,NFIL3,SIAH2,YWHAZ,CTSA,EHD4,SNRNP70,TOB1,N4BP2L2,ADNP2,TCF12,SMARCA4,ORC1,MXD1,USP5,HNRNPA2B1,SAP130,RRN3,UBXN2A,NVL,KIF14,EXOSC1,UTP4,ZNF770,CHP1,POU2AF1,UBQLN4,RNF25,SMU1,PCGF6,ATXN1,GLO1,EDEM2,TOLLIP,MBD3,RPS9,HNRNPR,STAT6,ARNTL,MAPK1,BRD9,NAT14,DNAJC2,TRIP12,ZNF316,RAE1,SCYL1,NUP54,PAWR,MXD4,DCUN1D4,FASTKD3,FGFR3,KMT5A,DUS2,NABP2,H2AFY,ARHGEF2,ANP32A,ATG13,LDLRAD3,STAT3,TGFB1,COA3,PHF20L1,PPP1R9B,DCAF6,PSPC1,HELB,MIER1,RFFL,RCOR1,PRMT2,CDK11A,TFEB,LEMD2,UPF1,KMT2B,CENPT,ZMIZ1,HRAS,SLF2,TERF1,FGFR1OP,MAP3K7CL,KDM4A,XIAP,EDRF1,PPP1R16B,PABPC4,CALM2,CDK5,CIPC,PSMD1,NSRP1,SRSF4,FNIP2,NUP153,SENP1,MLST8,PLK3,ZNF672,AATF,TOPORS,DCUN1D5,STOML2,BRMS1,AXIN1,LIMK1,ZNF689,PRDX5,VIPAS39,TRIM52,TFDP2,E2F2,AAAS,SSRP1,PHF23,EZH1,DDRGK1,MCTS1,PHF14,ZNF326,FOXN2,CYFIP1,ETV3,RB1CC1,ZMYND11,MYBL2,SRSF5,CBFA2T2,CSK,DUSP3,SETD3,CNOT6,RNF139,SGF29,EGLN1,ZNF207,PPP1R37,ZNF296,SARNP,TRERF1,IVNS1ABP,UBR2,WDTC1,MYH9,CREBL2,ZNF267,TCF19,PRKACA,SAFB2,APP,ANKIB1,SP100,ZKSCAN1,DDA1,NUP107,MAVS,RNF19A,CLN6,RBM15,ATF2,RNF169,ADCY7,SHOC2,PSRC1,MAP4K4,RNPS1,WBP2,CDCA2,DNAJA1,TAZ,DDX17,CHCHD3,TAF2,HIPK2,RPLP1,TICAM1,FUS,ZBTB11,LRP8,ZNF786,RPS2,TRAK1,GMCL1,JMJD6,AKT1S1,ETS1,ZNF92,SUV39H2,PPP1R8,PRDM4,DCP1A,PDPK1,PPP3CA,TNFAIP3,ZNF512,JTB,ZP3,ZNF180,ZNF862,KEAP1,PITX1,PML,LRPPRC,HMGB2,PSAP,USF2,IGBP1,FAF1,AGRN,THOC1,GPBP1L1,PPP1R15B,CSNK2A1,S1PR2,BIRC2,LIN9,PCNA,ZNF639,ETV6,PIK3R2,MYBL1,CCAR1,PTPRK,CDC37,SP3,EXOSC6,BAZ2A,PBXIP1,MRPL12,GMFB,EZR,LRP5,BRCA1,TONSL,SOCS4,ZNF45,LZTR1,CTCF,PPP3CB,RLF,CRLF3,ASXL2,LRRC14,RB1,MED8,TIGAR,TIMELESS,AFF1,MDFIC,MAML1,PREB,TRAPPC9,UTP15,RTF1,EIF2AK1,KRAS,NFATC2IP,EIF4G2,ZNF174,PSMC4,SYNCRIP,TBPL1,PRMT7,RNF114,CYLD,FOXM1,DYNLL1,SUMO2,DUSP22,COMMD8,RPL11,RAD23A,CSDE1,ZBTB21,MDM2,TNFAIP8,PDCD2,SAP30L,DVL2,TIMP2,PSMA8,BTG2,NFATC2,KDM1B,USP36,SRSF1,DNAJC10,CLK3,ZNF700,SCAP,TIMM17A,PSMD3,MAFK,DNAJC17,ZNF436,PLGRKT,NCOA1,ZNF146,CTDP1,MIF4GD,DAP,CDT1,ARID5A,NKRF,CSNK1A1,TFRC,WRNIP1,PTPN2,IRF4,SS18L1,PTGES3,ZNF202,ZMYM5,BIRC5,TWSG1,TFE3,CDCA7L,GLG1,PKD2,UBE2C,ZNF496,YTHDF3,CCNB1,EIF1B,COMMD6,RIC1,PARPBP,MAST2,CDC25B,PLCL2,DNMT1,SEH1L,AKT2,PBK,ELOA,MRNIP,DDX20,AURKB,TMED10,PSMD8,TRAF5,ARRB2,ZNF598,HDAC2,SVIP,DDX58,PPIB,HSPH1,GMFG,CHTF18,NOTCH2,PMF1,METTL3,JMY,NDUFS4,CFLAR,FKBP1A,MEX3C,KLF16,HDAC7,LPCAT1,GNAI2,EEF1D,TERF2,PHF10,ZNF84,CYFIP2,KDM3A,PSMB3,FAS,EPRS,SERTAD2,ZNF777,NSF,ZFP92,QARS,PPP3R1,TCOF1,PPP6R3,MAP3K5,YY1,CDK2,RNF14,ZC3HAV1,DNMT3A,RWDD1,ZBTB37,CAST,SUZ12,RPS6KA1,EIF3D,RAC1,MAGED1,PAIP2,TERF2IP,CRKL,APLP2,ZNF75D,KDM2A,SHC1,UCHL5,CDKN1B,CCT2,RFC3,ERF,TAOK1,CUL3,H2AFV,PSMB9,CENPU,SOCS7,PRDM11,VEZF1,PPP2R5A,STAT1,H2AFX,TRIM32,ATMIN,CSNK1D,RHEBL1,POLQ,POU3F2,NCOR2,TCF3,BABAM1,MYNN,BLM,FOXO3,MAD2L2,GTF2F1,RBM17,PTEN,MAP3K14,CREB1,CNOT6L,NCOA2,TSHZ1,ZFP64,NEK7,WDR18,PARP4,ILF3,TBRG4,MARK2,PRDX1,POLR2A,GNA12,HGS,PRDX3,TFDP1,KHSRP,BRWD3,CPEB2,IER2,NOP2,HNRNPAB,NF1,UBN1,DNAJC24,ZNF107,SIRT2,TAF6L,UBQLN2,MAPK14,SNAPC4,CYREN,RAP1A,EIF4A3,METTL14,PHTF1,SRI,ZBTB22,OGG1,ARID4A,TRIM14,ELOF1,COPS8,TRIM8,RRM2,SOX4,UBTF,GEMIN5,PAF1,PQBP1,ROCK1,RPS26,PSMC1,ZNF768,CIB1,TIA1,MED13L,MEF2A,SRRT,RHBDD1,APOPT1,NFATC3,ZNF449,BUD31,ZNF335,YBX1,BCL2,ACAD8,HP1BP3,ZNF189,VOPP1,CIC,OXR1,PSMA1,ISG15,CAND1,TSC1,RBM25,NSMF,NUP62,ZFP90,RBBP4,HNRNPDL,SMARCD1,ZBTB24,MBD1,ASH1L,MPHOSPH8,IFI27L1,PLAGL2,NSD3,IRF3,CHD1,PAIP1,MEAF6,BABAM2,AKAP8,PARL,CHTOP,F2R,ABI1,HTRA2,MOSPD1,RLIM,FAM172A,ZNF500,PSMB7,BOLA1,ERBIN,PEF1,BTBD1,ZNF317,TAB2,TULP3,GADD45B,SCARB1,AKNA,SMURF1,PPP2R2D,CBX4,MIF,EYA1,DBF4,KLF13,FBXO5,TANK,PELO,BRD7,SAMD4B,TELO2,HMGN1,ADAM17,PRKAR1B,MEN1,ZNF407,SYMPK,SNRPA,HSPA1B,MAPK3,CNOT9,PLAA,ATAD2,OSBPL8,ZRANB2,SRSF3 |
| 4.583e-12 | -26.11 | regulation of mRNA metabolic process | biological process | GO:1903311 | 289 | 90 | 17256 | 2622 |
RBM8A,YTHDF3,CCNB1,SAFB2,MAPK14,RBM4,PAIP1,PABPC4,PAPOLA,HNRNPA2B1,PSMA6,PSMD1,NSRP1,METTL14,SRSF4,EXOSC1,TRA2B,TARDBP,AHCYL1,SRPK2,PRPF19,SRSF10,EXOSC6,POLR2G,PSMA8,BTG2,SMU1,RNPS1,PSMB7,CIRBP,SREK1,PSMB9,IWS1,DDX17,PAF1,RPS27A,HNRNPR,PSMD8,SAFB,PSMD3,RNASEL,PSMC1,SRSF6,AGO2,DHX9,TIA1,JMJD6,SECISBP2,THRAP3,CDK11B,PARN,PSMD9,METTL3,CDC73,FASTKD3,PSMD2,EXOSC7,AXIN2,DCP1A,CTR9,ANP32A,YBX1,CPSF4,CNOT6L,PABPC1,RBM15B,SAMD4B,YTHDC1,RBM42,PSMA1,TBRG4,EXOSC9,FXR1,CDK11A,SLTM,SNRPA,PSMB3,PSMC4,UPF1,SYNCRIP,RBM25,RBMX,E2F1,KHSRP,YWHAZ,DDX5,SRSF3,SNRNP70,TOB1,ZC3HAV1 |
| 4.584e-12 | -26.11 | DHX9 (DExH-box helicase 9) | protein interactions | 1660 | 235 | 81 | 17029 | 2761 |
USP7,SART1,CYLD,THOC1,IVNS1ABP,SUZ12,RBM8A,CUL1,USP39,SND1,UBE2I,EIF1B,RBM4,BIRC2,PA2G4,MDM2,PCNA,TARDBP,CDC5L,SNRPB,CUL3,HNRNPF,DDX20,BRCA1,MCM2,RAB5B,RPSA,SRSF1,DDX17,HNRNPR,DGCR8,PSMD8,RPS14,H2AFX,ACTB,RRS1,SMURF1,RPS26,ZMAT3,SSRP1,PPIB,EWSR1,AGO2,DHX9,THRAP3,PSEN1,SRRT,WWP2,LYAR,KIF5B,RPA2,MCM5,MBD2,EFTUD2,ZNF746,RTCB,GEMIN4,MVP,HNRNPM,SPTAN1,TXNL1,STAU1,TMEM126B,PRKDC,SUGP2,ILF3,RPL6,RPS24,RPL27A,RHOT2,ABCF1,MATR3,SF3A2,POLR2A,RPA1,CAND1,XRCC5,QARS,DDX5,SRSF3,CDK2 |
| 4.664e-12 | -26.09 | GO_POSITIVE_REGULATION_OF_CATABOLIC_PROCESS | MSigDB lists | GO_POSITIVE_REGULATION_OF_CATABOLIC_PROCESS | 383 | 110 | 17377 | 2626 |
ATXN3,SUMO2,CUL1,CSNK2A1,SIRT2,UBQLN2,CCNB1,BECN1,ANKIB1,PARK7,BCAP31,TRIM65,EPM2A,FBXO22,USP5,MDM2,PSMD1,PSMA6,RALB,CDKN1B,ANAPC7,RNF19A,TIPARP,PLK3,PLK1,TRIM8,POLR2G,PSMA8,AKT2,BTG2,RAB7A,PSMB7,CUL3,EZR,CDC23,RAB1A,EDEM2,PSMB9,ABHD5,CDC16,HNRNPR,RPS27A,PSMD8,PSMD3,NSMCE2,AXIN1,SOCS4,ADAM9,STK11,ZNF268,TRIM32,CLU,DVL1,SMURF1,PSMC1,OAZ1,CSNK1D,SVIP,USP13,SCOC,GORASP1,GGA1,DNAJB2,PRKAA1,NKD2,EIF2AK4,CSNK1A1,PSMD9,PSEN1,PIP4K2A,RHBDD1,DDRGK1,FBXO5,RB1,PSMD2,PTEN,LRSAM1,LPCAT1,PABPC1,TPCN1,PHKG2,SOCS5,TNFAIP3,GBA,PIP4K2C,PSMA1,ANAPC2,ADRB2,PTTG1IP,PSMB3,SH3GLB1,MAPK3,PSMC4,TFEB,KEAP1,HSPBP1,UPF1,GOLGA2,CDC27,NSF,OAZ2,RNF14,UBE2C,CD81,RNF139,TOB1,ESPL1,ZC3HAV1,ANAPC4,RNF114 |
| 4.684e-12 | -26.09 | ncRNA processing | biological process | GO:0034470 | 419 | 118 | 17256 | 2622 |
SART1,KARS,DDX47,TP53RK,RPLP2,NOP2,LAGE3,EBNA1BP2,C2orf49,RPL23A,KRR1,RPL11,HNRNPA2B1,UTP25,PA2G4,NOL11,DUS4L,THADA,EIF4A3,UTP18,GRSF1,INTS1,TRMU,EXOSC1,POP7,RPF2,INTS12,UTP4,FTSJ3,MRM2,METTL1,RPP25,RPL29,RPL35,EXOSC6,NOL8,NSUN2,METTL2A,RPL38,ELP4,UTP3,PRKRA,GAR1,RPS9,MAK16,RPSA,DDX17,RPL37,NSA2,SMAD2,DUS3L,DGCR8,RPS27A,LSM6,TBL3,RPS14,WDR4,RPLP1,FTSJ1,RNASEL,RRS1,OSGEPL1,SMAD1,PDCD11,RPS26,CSNK1D,INTS2,SEPHS2,CTU2,RPS15,RPS2,RRP15,TRMT6,AGO2,RPL15,METTL3,SRRT,RRP36,PNO1,TUT4,KRI1,LYAR,GTPBP3,DDX56,EXOSC7,RPL17,INTS7,ELP5,DUS2,RTCB,RPL19,GEMIN4,CPSF4,FBL,MRM3,NSUN4,WDR18,TYW1,TEX10,RPL6,GTPBP4,UTP15,RPL8,RPS10,RPS24,BMS1,EXOSC9,RPL27A,TSR2,RPL36,UTP20,RPL32,TYW5,TRMT10B,TSEN15,BYSL,DDX52,TYW1B |
| 4.724e-12 | -26.08 | MED4 (mediator complex subunit 4) | protein interactions | 29079 | 359 | 110 | 17029 | 2761 |
CCNC,KARS,FGFR1OP,SKA3,CYLD,LUZP1,NOP2,WDTC1,MOGS,CNTROB,BRIX1,ATP6V1B2,EDRF1,SDE2,GIT2,DST,ANKRD26,DLG5,TNFAIP8,KIF14,TXLNA,HADHB,NSFL1C,CEP63,TCEA1,ECD,TP53BP2,PDIA6,SMARCE1,POC5,DVL2,CCAR1,POLR2G,CCDC138,LRBA,RNPS1,ERBIN,ERC1,EPB41,DPYSL3,SUPT16H,AHNAK,SEC61A1,CCDC14,CORO1C,PPM1G,CEP55,SH3GLB2,SNRPG,SASS6,ARRB2,XRCC4,CTDP1,NIFK,EWSR1,PDAP1,RAE1,DCTN2,MED13L,ATG2B,HAUS4,CYCS,THRAP3,DNAJB1,NCAPG,CNOT11,PIP4K2A,HAUS2,SPAG5,GTF2F1,KIF5B,RPA2,HOMER1,CTNNBL1,MED8,MED10,CCP110,HUWE1,MICAL3,MED22,SPTAN1,ATP5IF1,DENND4C,AMD1,CAMSAP1,PIP4K2C,ADSL,KRAS,BCLAF1,SRSF5,KIF11,CDK11A,CIP2A,POLR2A,RPA1,HAUS8,KEAP1,HSPBP1,PCM1,PDCD6,BIRC5,SNAP29,ODF2,MED15,EXOC4,SSNA1,NDE1,PDLIM5,SGF29,SMARCD1 |
| 5.210e-12 | -25.98 | REACTOME_MITOTIC_M_M_G1_PHASES | MSigDB lists | REACTOME_MITOTIC_M_M_G1_PHASES | 162 | 60 | 17377 | 2626 |
POLA2,MAPRE1,MCM10,GORASP1,CDT1,DBF4,CDCA8,KIF23,NUF2,KIF2C,PMF1,ORC1,PSMD9,MIS12,FBXO5,RPA2,PSMD2,PSMD1,SMC3,AHCTF1,PSMA6,MCM5,NUP107,KNTC1,CENPM,ORC3,NUP85,SEH1L,NUDC,PLK1,PRIM2,PSMA8,TAOK1,PSMB7,E2F3,PSMA1,CDC6,RANGAP1,AURKB,MCM2,PSMB9,PSMB3,PSMC4,RPA1,PRIM1,PPP2CA,KIF2A,KIF18A,PPP2R5A,POLE,DSN1,BIRC5,RPS27A,PSMD8,PSMD3,E2F1,CENPT,CDK2,E2F2,PSMC1 |
| 5.256e-12 | -25.97 | LI_WILMS_TUMOR_VS_FETAL_KIDNEY_1_DN | MSigDB lists | LI_WILMS_TUMOR_VS_FETAL_KIDNEY_1_DN | 158 | 59 | 17377 | 2626 |
NUP188,H2AFZ,EYA1,PTTG1,CENPF,UCK2,TPX2,RRM1,TIA1,KIF23,KIF2C,BLM,STMN1,MYL6B,NUP205,FANCI,SPAG5,KIFC1,DLG5,PCNA,IARS,KIF14,MSH2,TIMELESS,RNASEH2A,TP53BP2,STRAP,PCBP2,MSH6,SMC4,ANKLE2,NASP,PRIM2,BTAF1,MAP4K4,MKI67,DNAJC9,AURKB,BRCA1,CADM1,ESYT1,MCM2,KIF11,CHAF1A,XRCC5,PRIM1,DDX23,NAP1L1,MTHFD2,SLC16A1,BAZ1B,YWHAZ,KPNA2,CDK2,CCNB2,ESPL1,PFKP,SSRP1,DDX52 |
| 5.362e-12 | -25.95 | modification-dependent macromolecule catabolic process | biological process | GO:0043632 | 507 | 136 | 17256 | 2622 |
CUL1,UBE2Z,NHLRC3,SIRT2,UBQLN2,CCNB1,UBE2I,USP48,BIRC2,RNF103,FBXO22,PCYOX1L,PSMD1,RAD23B,PCBP2,USP34,PLK1,RBX1,TOPORS,USP22,AURKB,CCNF,USP21,RPS27A,PSMD8,AXIN1,ATE1,ARRDC1,VPS4A,KLHL42,FBXL3,ARRB2,PSMC1,UBE2D3,RMND5A,TMUB1,UBXN1,KCTD17,ZNRF3,PSMD9,VPS25,NPLOC4,DTL,RNF121,EXOSC7,ZNRF2,FBXO7,FBXL7,ZRANB1,ERLIN1,MAN1B1,PSMA1,USP10,EXOSC9,UBE4B,SYVN1,ARMC8,PSMB3,ISG15,PSMC4,DERL1,CDC27,KLHL15,SIAH2,DCAF11,USP32,ECPAS,RNF139,USP7,ATXN3,CYLD,UBR2,PTTG1,RAD23A,USP5,UBXN2A,MDM2,PSMA6,SIAH1,UCHL5,KIF14,MTA1,NSFL1C,ANAPC7,TTC3,SPSB3,RLIM,SEC61B,PSMA8,PSMB7,CUL3,CDC23,EDEM2,TOLLIP,PSMB9,USP36,BTBD1,ANKZF1,DNAJC10,CDC16,PSMD3,UBXN2B,ARNTL,SEL1L,RNF38,TRIM32,USP11,SMURF1,USP13,TRIP12,UBE4A,CSNK1A1,DNAJB9,WWP2,PSMD2,KLHL20,LTN1,GTSE1,FBXL19,RNF5,TNFAIP3,USP42,FBXO9,RFFL,ANAPC2,WDR81,FBXO21,PLAA,PML,PPP1R11,USP20,WDR91,UBE2C,ANAPC4,FAF1,DDB1 |
| 5.707e-12 | -25.89 | RPL6 (ribosomal protein L6) | protein interactions | 6128 | 265 | 88 | 17029 | 2761 |
CYLD,NOP2,RPLP2,IVNS1ABP,CUL1,CSNK2A1,EBNA1BP2,BRIX1,PABPC4,RPL11,RPL23A,KRR1,MDM2,EIF4A3,MRPS27,MRPL34,TARDBP,FTSJ3,SRSF10,FYTTD1,RPL29,SEC61B,BRD4,RPL35,RPL38,RNPS1,CUL3,BRCA1,SLC25A5,MRPS14,RPS9,RPSA,DAP3,RPS27A,RPS14,MRPL27,RPLP1,SEL1L,CHMP4B,COPS6,RRS1,ARRB2,MRPL13,ZBTB11,RPS26,RPS15,RPS2,MRPL9,MRPL42,MRPS2,MRPS26,DHX9,RPL15,LMNA,KRI1,RPA2,HUWE1,RPL17,AHSA1,RBM34,ZNF746,LTN1,YBX1,RPL19,MAP3K14,FBL,PABPC1,HNRNPM,STAU1,DDX24,ABCF2,RPS10,GTPBP4,RPL8,ILF3,TUFM,RPS24,RPL27A,RPA1,CAND1,RPL36,EPRS,NAP1L1,UPF1,MAGT1,RPL32,CDK2,CD81 |
| 5.754e-12 | -25.88 | CACGTG_V$MYC_Q2 | MSigDB lists | CACGTG_V$MYC_Q2 | 960 | 223 | 17377 | 2626 |
ZBTB10,PDCD6IP,MAX,PPCS,H2AFZ,TSC2,ADAM10,EBNA1BP2,GYG1,TAF6L,SLC20A1,MIEN1,SYNRG,KCMF1,PABPC4,SLC25A37,SSR1,CDKN2C,PA2G4,NEK6,ATG3,ZNHIT6,SUCLG2,JOSD1,NUP153,SLC26A2,ZNF800,CCAR1,TIMM50,USP34,SRP72,RHOBTB3,NRAS,KLF10,AATF,LAP3,NOL8,HSDL1,GMFB,HNRNPF,TOPORS,ESYT1,PBRM1,KRTCAP2,MCM2,ODC1,EIF3A,EPB41,HHEX,SMAD2,BRD2,TMED10,MRPL27,OGT,MPV17,BCL7C,RRS1,CLN3,NUDT11,B4GALT2,SLC25A33,HSPH1,TMUB1,EWSR1,UBXN1,GADD45G,RLF,RAPGEF6,FAM192A,TFAP4,LYAR,NFATC3,SMC3,SLC38A5,ARPC5,ZNRF2,ATIC,EFTUD2,MEA1,YBX1,RBM3,PIK3IP1,GEMIN4,MRPL40,ALDH18A1,ANKHD1,PABPC1,SOCS5,MAPKAPK3,SIGMAR1,C16orf72,AMD1,SUGP2,ZNF574,UBE4B,FXR1,ELK1,KDM3A,PSMB3,EVC2,HMGN2,AKAP1,RXRB,ADSS,GNAS,TSC1,SYNCRIP,CSK,PRPS2,LPCAT4,ACLY,DCAF11,CTSA,TCOF1,RBBP4,HEXA,ZNF296,ATXN3,DNMT3A,TRIP10,RRAGC,SNN,LCLAT1,ZADH2,STMN1,COMMD8,GNB2,CSDE1,ATP6V0B,PDK2,CD3EAP,UTP18,TNPO2,CEP63,FAM76B,DVL2,CFL1,SNX8,ARHGAP17,POLR2L,ERF,WBP2,E2F3,NLN,PFKFB3,NDUFA7,GAR1,MAT2A,USP36,SUPT16H,C19orf54,ALDH3B1,HSPA4,RAB24,HPS5,GADD45B,FKBP5,ZBTB11,LRP8,ABCA1,RHEBL1,ATXN7L2,POU3F2,RPS2,NDUFS1,ANXA6,RRP15,SCAMP3,ZFP91,SCYL1,TRMT6,SUMF1,MXD4,DCUN1D4,FOXO3,TFRC,DNAJB9,JAKMIP1,WWP2,PPP1R3B,PRDM4,RPL19,TAGLN2,FBL,CITED2,STAT3,CNPY3,FBXL19,HNRNPM,NUDC,RBM15B,B3GALT6,AMPD2,ELOVL5,PPP1R9B,PHF20L1,LONRF3,SNX2,NET1,SCFD2,LDHA,ILF3,HEBP2,C14orf132,PICALM,TSR2,SNRPA,RPA1,SEC23IP,SLC38A7,CCDC6,HNRNPH3,AEN,DDX5,ASNA1,RGL1,ATP6V1C1,UBE2C,THAP5,GCSH,RAB3IL1,IPO4,FAF1 |
| 5.822e-12 | -25.87 | GSE3982_MAC_VS_TH1_DN | MSigDB lists | GSE3982_MAC_VS_TH1_DN | 187 | 66 | 17377 | 2626 |
CYTIP,IER2,ASH1L,CXXC1,ORC1,STMN1,BECN1,RPL11,XRCC2,TAP2,AQR,NAA35,CDC123,SNRPB,EZR,WDR82,NUSAP1,NUP155,PKMYT1,ASF1B,USP36,GINS4,CDCA4,DGCR8,GOLGA8A,BCL7C,PQBP1,PRPF4,DMWD,TFDP2,TRAF5,TUBB,FUBP1,PPP1R2,CLSPN,SRSF6,FLOT1,RRM1,CTCF,KIF23,TIA1,PXMP2,CRLF3,C12orf10,ERH,PPP1R8,PRC1,ZDHHC13,TIMELESS,CNN2,KNTC1,ALDH18A1,POLR2I,TK1,TSTA3,SSR2,EIF2AK1,RHOT2,SNRPA,PRDX3,BIRC5,CSNK1G1,ODF2,GPI,PPP6R2,DEF6 |
| 5.870e-12 | -25.86 | GO_ORGANELLE_INNER_MEMBRANE | MSigDB lists | GO_ORGANELLE_INNER_MEMBRANE | 466 | 127 | 17377 | 2626 |
NDUFA5,COX15,IMMT,NDUFB6,SUCLG1,MRPS15,NDUFAF2,MRPL39,UQCR10,MDH2,TOR1AIP1,MCCC1,ABCB10,BCL2L1,SLC25A44,LYN,SDHA,MRPL19,PARK7,SLC25A37,CSDE1,MRPL50,TIMM23,GOT2,MRPS27,MRPL34,HADHB,PARL,NDUFB9,APOOL,MRPL32,TIMM50,ACSL5,PPIF,COQ10B,CPOX,MRPL12,MRPL43,VDAC2,SLC25A22,NDUFA7,NDUFB1,VDAC1,SLC25A5,TAZ,MRPS14,FOXRED1,TMEM201,STOML2,CHCHD3,MRPL2,DAP3,TIMM13,MRPL55,TIMM17A,CHCHD1,MRPL27,NDUFA11,NRM,MPV17,COX5A,UQCRH,SMAD1,MRPL13,SLC25A39,SLC25A33,COX5B,NDUFV2,MRPL9,NDUFS1,CDS2,MRPL42,PHB2,MRPS26,SLC25A12,NDUFA4,CYCS,COX4I1,PSEN1,SLC25A43,NDUFS7,NDUFS4,SLC25A36,GSTK1,NDUFV1,NDUFA2,COQ4,NDUFB4,CRAT,BDH1,MRPL54,NDUFS8,CYC1,MRPL48,MRPL40,ALDH18A1,MRPL11,MRPL21,NDUFA3,STAT3,SLC25A1,NIPSNAP1,TIMM8B,TIMMDC1,SIGMAR1,NOA1,PGS1,TMEM126B,MRS2,MRPS10,MRPL16,GUF1,CHCHD6,MATR3,SFXN5,AKAP1,CBX3,LEMD2,SDHB,COX7A2L,LRPPRC,COX8A,ACAT1,SLC25A19,NDUFS5,MRPL3,HIGD2A |
| 5.879e-12 | -25.86 | ubiquitin-dependent protein catabolic process | biological process | GO:0006511 | 488 | 132 | 17256 | 2622 |
CUL1,UBE2Z,NHLRC3,SIRT2,UBQLN2,CCNB1,UBE2I,USP48,BIRC2,RNF103,FBXO22,PSMD1,RAD23B,PCBP2,USP34,PLK1,RBX1,TOPORS,USP22,AURKB,CCNF,USP21,RPS27A,PSMD8,AXIN1,ATE1,ARRDC1,VPS4A,KLHL42,FBXL3,ARRB2,PSMC1,UBE2D3,RMND5A,TMUB1,UBXN1,KCTD17,ZNRF3,PSMD9,VPS25,NPLOC4,DTL,RNF121,ZNRF2,FBXO7,FBXL7,ZRANB1,ERLIN1,MAN1B1,PSMA1,USP10,UBE4B,SYVN1,ARMC8,PSMB3,PSMC4,DERL1,CDC27,KLHL15,SIAH2,DCAF11,USP32,ECPAS,RNF139,USP7,ATXN3,CYLD,UBR2,PTTG1,RAD23A,USP5,UBXN2A,MDM2,PSMA6,SIAH1,UCHL5,KIF14,MTA1,NSFL1C,ANAPC7,TTC3,SPSB3,RLIM,SEC61B,PSMA8,PSMB7,CUL3,CDC23,EDEM2,TOLLIP,PSMB9,USP36,BTBD1,ANKZF1,DNAJC10,CDC16,PSMD3,UBXN2B,ARNTL,SEL1L,RNF38,TRIM32,USP11,SMURF1,USP13,TRIP12,UBE4A,CSNK1A1,DNAJB9,WWP2,PSMD2,KLHL20,LTN1,GTSE1,FBXL19,RNF5,TNFAIP3,USP42,FBXO9,RFFL,ANAPC2,WDR81,FBXO21,PLAA,PML,PPP1R11,USP20,WDR91,UBE2C,FAF1,DDB1,ANAPC4 |
| 6.077e-12 | -25.83 | modification-dependent protein catabolic process | biological process | GO:0019941 | 498 | 134 | 17256 | 2622 |
CUL1,UBE2Z,NHLRC3,SIRT2,UBQLN2,CCNB1,UBE2I,USP48,BIRC2,RNF103,FBXO22,PCYOX1L,PSMD1,RAD23B,PCBP2,USP34,PLK1,RBX1,TOPORS,USP22,AURKB,CCNF,USP21,RPS27A,PSMD8,AXIN1,ATE1,ARRDC1,VPS4A,KLHL42,FBXL3,ARRB2,PSMC1,UBE2D3,RMND5A,TMUB1,UBXN1,KCTD17,ZNRF3,PSMD9,VPS25,NPLOC4,DTL,RNF121,ZNRF2,FBXO7,FBXL7,ZRANB1,ERLIN1,MAN1B1,PSMA1,USP10,UBE4B,SYVN1,ARMC8,PSMB3,ISG15,PSMC4,DERL1,CDC27,KLHL15,SIAH2,DCAF11,USP32,ECPAS,RNF139,USP7,ATXN3,CYLD,UBR2,PTTG1,RAD23A,USP5,UBXN2A,MDM2,PSMA6,SIAH1,UCHL5,KIF14,MTA1,NSFL1C,ANAPC7,TTC3,SPSB3,RLIM,SEC61B,PSMA8,PSMB7,CUL3,CDC23,EDEM2,TOLLIP,PSMB9,USP36,BTBD1,ANKZF1,DNAJC10,CDC16,PSMD3,UBXN2B,ARNTL,SEL1L,RNF38,TRIM32,USP11,SMURF1,USP13,TRIP12,UBE4A,CSNK1A1,DNAJB9,WWP2,PSMD2,KLHL20,LTN1,GTSE1,FBXL19,RNF5,TNFAIP3,USP42,FBXO9,RFFL,ANAPC2,WDR81,FBXO21,PLAA,PML,PPP1R11,USP20,WDR91,UBE2C,ANAPC4,FAF1,DDB1 |
| 6.079e-12 | -25.83 | GSE31082_DN_VS_DP_THYMOCYTE_UP | MSigDB lists | GSE31082_DN_VS_DP_THYMOCYTE_UP | 183 | 65 | 17377 | 2626 |
TMEM106C,SEC61G,CDK2AP2,UCK2,POMP,IFT27,WRB,MRPL19,TUBGCP2,PARK7,HDDC2,RPL23A,PSMD1,CD3EAP,NUP107,MECR,MRPL34,CS,GPATCH1,YIF1B,MRPL48,PRADC1,METTL9,ERI3,MRPL11,PPIF,CCT2,LARS,GTF3C6,RPL35,SIGMAR1,METTL5,MRPL12,LDHA,EXOSC9,MRPL16,ABHD11,BMS1,METTL22,TXNL4A,API5,CHCHD6,FKBP3,ZDHHC3,EIF3A,STOML2,ALG3,EPRS,HINT1,POLR2J,LSM6,PDRG1,TOMM6,CHCHD1,WDR4,RWDD4,E2F1,MBOAT1,GPI,NAA20,EHD4,PDSS2,NMD3,NUDT3,PDF |
| 6.321e-12 | -25.79 | GSE20152_SPHK1_KO_VS_WT_HTNFA_OVERXPRESS_ANKLE_DN | MSigDB lists | GSE20152_SPHK1_KO_VS_WT_HTNFA_OVERXPRESS_ANKLE_DN | 179 | 64 | 17377 | 2626 |
RHOG,ANKRD27,NAT9,PPCS,C19orf53,GOLPH3L,PTTG1,YTHDC2,MOGS,CTCF,TBC1D13,SDF2L1,FAM136A,GGA2,XPO7,SUPT7L,PSMD9,GGPS1,RSAD1,LRRC14,PCYOX1L,ERH,PA2G4,CLUAP1,SNUPN,SMC3,TNFAIP8,NVL,CRAT,ATIC,EI24,SLC38A10,ACAD8,SLC35A1,PREB,NUDC,EBAG9,CPNE1,TELO2,PTPN18,TMEM115,MLEC,CSRP1,TSTA3,PIP4K2C,ESYT1,FXR1,AKAP1,CAND1,C19orf54,ZNF180,FBXO21,FNTA,SYNCRIP,PTER,ARNTL,BBX,MEGF9,BAZ1B,FN3KRP,GALNT10,YWHAH,CCNB2,SSRP1 |
| 6.460e-12 | -25.77 | nucleus organization | biological process | GO:0006997 | 146 | 56 | 17256 | 2622 |
CHMP2A,NDC1,NUP188,PDCD6IP,RAE1,TOR1AIP1,NUP54,AGFG1,CCNB1,ETS1,LMNA,NUP205,GOLM1,RRN3,ANKLE1,UBXN2A,AHCTF1,NUP210,NEK6,BANF1,NUP107,NSFL1C,NUP153,TARDBP,POLR1B,NUP85,SEH1L,DCTN1,SRPK2,PLK1,ANKLE2,FAM118B,NUP155,PITPNB,CHMP2B,KDM3A,USP36,LEMD2,PPP2CA,CHMP4A,UBXN2B,HIPK2,CEP55,PML,TBPL1,NUP62,CHMP4B,HMGB2,VPS4A,H3F3A,REEP4,CCNB2,CHMP7,NUP58,AAAS,TMEM33 |
| 6.532e-12 | -25.75 | IVANOVA_HEMATOPOIESIS_LATE_PROGENITOR | MSigDB lists | IVANOVA_HEMATOPOIESIS_LATE_PROGENITOR | 501 | 134 | 17377 | 2626 |
CCNC,DHX8,UBE2Q1,SLC29A1,COMMD5,OAT,CCNB1,SYNRG,ELMOD2,LIN9,CDK5,NAPG,C18orf32,CDC42,RABGAP1L,TTC9C,HADHB,CISD2,CDC25B,NFU1,PRADC1,SEH1L,ABCC5,PBK,TLK1,TMEM216,CKAP2L,CDC6,PITPNB,MCM2,PLEKHF2,ASF1B,NECAP2,ARRDC1,PIEZO1,GALNT10,OSGEPL1,PSMC1,POT1,ATP6V0E1,SLC25A33,SVIP,ZCCHC8,UFC1,LAMTOR3,TMED3,XPNPEP3,TMEM165,NUP205,APOPT1,DTL,SLC38A5,DAD1,OSTF1,CSNK1G3,EEF1D,TMED2,NSDHL,SEPT8,MRPL16,ANKRD46,MASTL,ADSS,KPNA1,ORMDL2,TTC13,PIAS2,FAM122A,KCTD7,GGNBP2,CKLF,TMX4,GPR89A,UROD,NUF2,TWF2,APP,RPAIN,MEAF6,ANKRD28,MRPL50,UBXN2A,ATP6V0B,BCAP29,CABLES2,LMAN1,MINPP1,TMEM14C,SAP30,SNX8,CDC123,RAB7A,CPOX,SLBP,CCDC127,SRSF1,DAP3,CERS6,CAMKMT,FTSJ1,WDR7,ATF6,PITRM1,MAPK1,LTA4H,PRPF4B,TMEM33,NADSYN1,SMAP1,DAP,GMCL1,GGA2,AP3S1,TFRC,CCDC28A,RFWD3,CTSS,NDUFV1,GATC,MTX2,RHOA,TK1,TACC1,ATP2C1,MRPS10,API5,PRDX3,BIRC5,CTBS,ASNA1,DUSP11,ATP6V1C1,ESPL1,GPR89B |
| 6.544e-12 | -25.75 | GSE21546_ELK1_KO_VS_SAP1A_KO_AND_ELK1_KO_DP_THYMOCYTES_DN | MSigDB lists | GSE21546_ELK1_KO_VS_SAP1A_KO_AND_ELK1_KO_DP_THYMOCYTES_DN | 175 | 63 | 17377 | 2626 |
POLA2,DNAJC2,MCM10,RWDD1,CHERP,TOR3A,TMEM109,RRM1,STARD7,JMJD6,SLC29A1,GGA2,BLM,TCF19,TTF1,SPAG5,RBM17,SNRNP25,CTNNBL1,COQ4,CENPJ,MCM5,SIVA1,ATIC,BUD31,PPP6C,TIMELESS,KNTC1,CPSF4,TTLL12,LRRC59,NUP85,HNRNPM,TIMM50,PPIF,PPAN,PSRC1,RPRD1A,ASPM,ERLIN1,DNAJC9,NUSAP1,GLO1,AURKB,PRPF3,BRCA1,MCM2,CCNF,PATL1,CHAF1A,XRCC5,DDX23,HAUS8,CDCA4,DUS3L,WDR4,CDCA5,PRPF4,NDE1,REEP4,CABLES1,CCDC59,POLQ |
| 6.629e-12 | -25.74 | MATR3 (matrin 3) | protein interactions | 9782 | 188 | 69 | 17029 | 2761 |
CYLD,COPA,MPHOSPH8,EIF3D,HNRNPUL2,CUL1,UBE2I,SAFB2,PCBP1,MRPL19,HNRNPA2B1,EIF4A3,AKAP8,CRY2,TARDBP,RBM12B,SRPK2,HNRNPF,SMU1,CUL3,BRCA1,STOML2,DDX17,TIMM13,HNRNPR,SAFB,IARS2,H2AFX,FUS,BTF3,RRS1,FAM208A,UNK,EWSR1,PKP4,DHX9,EIF2AK4,LMNA,RPA2,SUB1,GSTK1,MCM5,ZNF326,RTCB,YBX1,RBM3,NAP1L4,HNRNPM,EEF1D,RBM15B,DDX28,STAU1,SUGP2,ILF3,MATR3,SLTM,SNRPA,CAND1,RPA1,SNAP23,RBMX,HNRNPH3,DDX5,ATP5F1A,RUVBL2,SRSF3,SNRNP70,CDK2,HNRNPDL |
| 6.865e-12 | -25.70 | APP (amyloid beta precursor protein) | protein interactions | 351 | 2125 | 456 | 17029 | 2761 |
RAB14,NDUFB6,USP39,IKBIP,UBE2I,ANKRD39,KIFC1,CDK5,UTP25,USF1,NAPG,NOL11,GSDMB,NSRP1,THAP4,DNAAF2,PDS5B,DNM2,CISD2,MAST2,MOB1A,LRRC59,SENP1,NOL12,ERCC1,GABPA,AKT2,DDX20,AURKB,SLC17A5,DIDO1,MCFD2,MCM2,ZFAND5,RAB2B,PLEKHF2,STOML2,ZMYM3,BRMS1,TRIM47,MKNK1,RPS27A,LIMK1,RPS14,PRDX5,MRPL27,PTPN7,BTF3,TRIM52,SMAD1,ZNF75A,CCDC59,ZMAT3,DDX42,NXT2,ZNF720,C9orf78,MAPRE1,MRPS2,POLR2K,GGA1,GSPT2,GADD45G,CERK,NDUFA4,SLC35B1,PDCD7,PSEN1,NDUFS4,DDRGK1,RTKN,FKBP1A,EIF2S2,EXOSC7,LRRC8D,MCM5,RBM34,BDH1,PIGG,FBXL7,OSTF1,PIKFYVE,MRM3,LUC7L2,EEF1D,SOCS5,ETV3,RBM42,MAPKAPK3,SF3B6,RPS10,ZNF574,PIP4K2C,C1orf35,FAM133B,GORASP2,MAP7D1,PKM,CBFA2T2,MPG,ELK1,GOSR1,PATL1,ABCF1,CCT8,AKAP1,PI4K2A,DTWD1,CAT,DERL1,OSBPL11,HSPBP1,DUSP3,CSNK1G1,QARS,SETD3,ACLY,ARAP1,PPP6R2,YY1,MAP3K5,RUFY3,MRPL3,ZC3HAV1,EXOC3,TRIM41,ATXN3,RAB11B,TMEM97,C2orf49,TCF19,RCOR3,APP,PAIP2,ARL6IP6,DECR1,CLUAP1,SHC1,ZKSCAN1,UCHL5,INTS12,TAP2,TP53BP2,ATF2,GCC1,ZC3H3,ARL5A,CFL1,ATP6V1G1,SHOC2,PSRC1,MAPRE2,KAT7,DRAP1,VDAC2,CIRBP,CUL3,NARF,NUSAP1,GORAB,ABHD11,MEF2D,H2AFV,ERC1,SERP1,DDX17,ANKZF1,RAD51C,HSPA4,DSN1,ACYP1,DGCR8,CCDC14,LSM6,GUCY1B1,FAAP100,CAMKMT,FTSJ1,ATF6,PPP5C,COIL,DYNC1LI2,CSNK1D,TUBB,GALK1,ANKRD13D,ZNF445,SCAMP3,C1orf112,SRSF6,CDCA3,FLOT1,AGPAT3,ARGLU1,SECISBP2,WDR5,ETS1,ZNF92,EBP,MAT2B,RFWD3,RPA2,ERH,DNAJC8,NDUFA2,PPP1R8,AHSA1,ANXA5,COPS7B,KANSL2,TAGLN2,CARF,UBE2M,LYPLA2,PDPK1,STAU1,TK1,TRIR,TMEM126B,KIAA0930,JTB,LLPH,LRRC1,KLF6,ECH1,SH3GLB1,SH3BP5,GNA12,HGS,KEAP1,C1orf131,CCZ1B,C4orf46,HMGB2,RGL1,IGBP1,WDR45B,TAF6,HIGD2A,VPS29,BYSL,IPO4,DEF6,POLA2,UBL3,PTMS,UBE2E2,SKA3,DDX47,NF1,AAMDC,RBM8A,ZNF107,CSNK2A1,KIF2C,AGFG1,SND1,USP48,CDIPT,MRPL19,FANCI,SF3B2,BCAT2,TET3,RAB35,SIVA1,PIK3R2,POP7,NOC2L,HADHB,GPATCH1,RPF2,ZFYVE27,TCEA1,EIF5,ASB6,SRPK2,CDC37,PLK1,SEPT9,LAP3,RBX1,VHL,RAD51AP1,TMEM216,RIOX2,ARHGDIB,PBRM1,KRTCAP2,STK17B,EPB41,NECAP2,RPL37,CXXC4,SEPT1,BRWD1,SPATA2,BCL7C,IARS2,PQBP1,ACBD4,ARRDC1,STK11,PRPF4,KPNA2,CHEK2,CLU,DNAJC30,NGLY1,PSMC1,RPS26,NUMB,RMND5A,TMUB1,ZCCHC8,KLC1,COX4I1,DNAJB1,ASXL2,SRRT,CHKA,SUB1,MLX,TIGAR,MED8,ZNF449,SSBP3,PPIL2,BUD31,AHDC1,MRPL48,UBE3C,HP1BP3,TRAPPC9,ACSL3,PSMA1,KRAS,RTF1,EIF2A,SYVN1,NMT2,ARHGAP15,HAUS8,RPL36,C22orf46,PAXX,GOLGA4,SYNCRIP,ODF2,TBPL1,ZDHHC7,FAM122A,FN3KRP,YWHAZ,RUVBL2,ATP5F1A,SNRNP70,PDSS2,TOB1,MBD1,SNX27,SART1,PRKAB1,NDUFA5,HCFC1R1,PCBP1,ZADH2,BCAP31,MXD1,RPL11,USP5,MDM2,IARS,SAR1A,PIN1,EXOSC1,MRPL34,TARDBP,LMAN1,CHTOP,FAM3A,UTP4,HTRA2,ARHGAP17,MND1,CYP20A1,NLN,BOLA1,NDUFB1,RPS9,EIF3G,SRSF1,GLOD4,IDE,DUS3L,DHX16,CLK3,TAB2,FKBP5,XRCC3,GAS2,SMURF1,CHID1,TSPAN5,ZC3HC1,KIF3B,CMAS,MCM10,SMAP1,MAGEH1,RRP15,CASP6,PDAP1,SCYL1,CDK2AP2,TMX3,ARFIP2,LETMD1,CHAC2,GGA2,PAGR1,DNAJB9,RGS1,FERMT3,PTPN2,MZT2A,SEC24C,TMA7,TANK,H2AFY,ATG13,ORC3,MRPL11,FRMD8,RPAP3,TGFB1,PPAN,CSNK1G2,PHF20L1,GTF3C6,CSRP1,TIMMDC1,ZMYM5,MIER1,HAGH,CHCHD6,CACNB1,TPD52L2,KPNA4,BBX,CENPT,RBPJ,SRSF3,GUCD1,IFI16,NXPE3 |
| 6.875e-12 | -25.70 | GNF2_CDC20 | MSigDB lists | GNF2_CDC20 | 54 | 30 | 17377 | 2626 |
PLK1,FOXM1,ASPM,PTTG1,CENPF,TPX2,CDCA3,MKI67,RRM1,CDCA8,RRM2,RACGAP1,NUSAP1,KIF2C,AURKB,SMC2,MCM2,SHCBP1,KIF11,SPAG5,PCNA,CCNA2,KIF18B,BIRC5,H2AFX,PRC1,CCNB2,UBE2C,ESPL1,SMC4 |
| 6.880e-12 | -25.70 | GO_CHROMOSOMAL_REGION | MSigDB lists | GO_CHROMOSOMAL_REGION | 306 | 93 | 17377 | 2626 |
ZNF207,SKA3,DNMT3A,THOC1,KDM4A,DYNLL1,NUF2,KIF2C,SIRT2,ORC1,CCNB1,MIS12,TERF2IP,OIP5,PCNA,AHCTF1,SP100,NUP107,PDS5B,KIF22,DNMT1,SEH1L,DCTN1,PLK1,ERCC1,MKI67,WDR82,AURKB,DCLRE1C,MCM2,GAR1,PPP2CA,PPP2R5A,DSN1,NSMCE2,H2AFX,BAZ1B,XRCC3,CHEK2,H3F3A,POT1,RAD51D,NSMCE4A,PPP1R12A,HJURP,CENPF,DCTN2,CDCA8,CTCF,SMC6,PMF1,BLM,CSNK1A1,PSEN1,CDC73,SPAG5,WRNIP1,RPA2,SMC3,SUV39H2,MCM5,MSH2,H2AFY,SS18L1,KNTC1,CENPM,PTGES3,ORC3,NUP85,TERF2,TELO2,PRKDC,RANGAP1,WDR81,SEPT7,MEN1,PHF6,RPA1,CBX3,XRCC5,KIF18A,UPF1,BIRC5,ZNF330,CDCA5,PML,CENPT,MBD6,NDE1,CDK2,TERF1,PURA,DDB1 |
| 6.930e-12 | -25.70 | LDHB (lactate dehydrogenase B) | protein interactions | 3945 | 142 | 57 | 17029 | 2761 |
MIF,EWSR1,HNRNPAB,PHB2,RPS6KA1,SUZ12,UFC1,TKT,NIT2,ARF1,SDHA,PARK7,HNRNPA2B1,PTEN,HUWE1,PPME1,ARF5,AHSA1,ZNF746,PPP4R1,AHCY,TALDO1,ATF2,CFL1,LDHB,STAU1,PPT1,WDR1,LDHA,CUL3,ADSL,UBE2V1,BRCA1,DNAJA1,PKM,MCM2,RAB1A,EIF4H,RHEB,ARF4,GINS4,CAT,IDE,PEX5,PRDX5,H2AFX,HMGB2,MDH1,YWHAZ,ACADM,FUS,NANP,CDK2,ECPAS,SMURF1,POT1,TERF1 |
| 7.143e-12 | -25.66 | MORF_NME2 | MSigDB lists | MORF_NME2 | 147 | 56 | 17377 | 2626 |
MIF,COX5B,RPLP2,PDAP1,SUMO2,NACA,RPL15,COX4I1,UBE2I,RPL11,RPL23A,NDUFA2,RPL17,HUWE1,ARF5,BANF1,RPL19,CYC1,PABPC1,EEF1D,LYPLA2,PCBP2,CFL1,RPL35,SNRPB,RPL8,JTB,RPS10,RPL38,LDHA,RPL6,SSR2,RPS24,TMEM147,RPL27A,EIF4G2,RPS9,STOML2,HMGN2,GNAS,HINT1,RPL32,RPS27A,PSMD8,RPS14,COX7A2L,COX8A,ACTB,YWHAZ,SSNA1,BTF3,COPS6,FAU,PSMC1,MYL12B,OAZ1 |
| 7.286e-12 | -25.65 | GSE27859_DC_VS_CD11C_INT_F480_INT_DC_DN | MSigDB lists | GSE27859_DC_VS_CD11C_INT_F480_INT_DC_DN | 192 | 67 | 17377 | 2626 |
NUP188,RBM8A,MOGS,TMEM109,TAF6L,CMTM6,PABPC4,ANKRD28,PCNA,AHCTF1,EIF4A3,UTP18,SLC44A1,NOL12,PLK1,ATP13A1,MKLN1,AATF,NSUN2,PCGF6,WDHD1,SMC2,NUTF2,GFER,DHX15,CLNS1A,EIF4ENIF1,MAFK,PSMD3,RNF38,BAZ1B,PSMC1,POT1,TUBB,SSRP1,MIF,RECQL,CTDP1,POLR2K,MECP2,KCTD17,PPP3CB,COPG2,HEATR5B,PTEN,FUT8,ZNF326,NDUFS8,NUP85,TPCN1,MYO5A,GINS1,KAT2A,PSPC1,TBRG4,MRPL16,KRAS,MTX1,SEPT7,SF3A2,PSMB3,CBX3,CAND1,MAPK6,TFDP1,PRMT7,BYSL |
| 7.447e-12 | -25.62 | viral gene expression | biological process | GO:0019080 | 127 | 51 | 17256 | 2622 |
RPS15,NDC1,NUP188,RPS2,RPLP2,RAE1,EIF3D,DHX9,NUP54,MON1B,RPL15,EIF2AK4,NUP205,MCTS1,RPL23A,RPL11,USF1,NUP210,RPL17,NUP107,RPL19,NUP153,NUP85,PCBP2,SEH1L,EIF3L,RPL29,RPL35,RPL6,RPL8,RPL38,RPS10,RPS24,NUP155,RPL27A,EIF3G,RPS9,EIF3A,RPSA,RPL36,RPL37,RPL32,RPS27A,RPS14,EIF2D,RPLP1,NUP62,USF2,RPS26,NUP58,AAAS |
| 7.544e-12 | -25.61 | GO_PROTEIN_UBIQUITINATION | MSigDB lists | GO_PROTEIN_UBIQUITINATION | 607 | 155 | 17377 | 2626 |
MIB2,CCNC,UBE2E2,DCAF15,TRIM11,XIAP,CUL1,UBE2Z,UBE2Q1,CCNB1,BIRC2,RNF103,FBXO22,ZER1,FANCL,PSMD1,CDC42,ATG3,FBXW2,MARCH2,ASB6,RYBP,PLK1,TRIM8,RBX1,VHL,TOPORS,UBE2V1,AURKB,BRCA1,USP22,CCNF,CBFB,TRIM4,PAF1,RAD18,RPS27A,PSMD8,TPP2,SOCS4,FBXL3,ARRB2,TRAF5,PSMC1,DCAF5,WSB2,UBE2D3,ZNRF3,PSMD9,CDC73,DTL,RNF121,UBE2Q2,MED8,MED10,KLHL5,ZNRF2,PPIL2,FBXO7,CTR9,FBXL7,BCL2,UBE3C,RNF135,LRSAM1,UBE2QL1,SOCS5,DCAF8,PSMA1,UBE4B,SYVN1,PSMB3,PSMC4,CAND1,CDC27,KLHL15,SIAH2,DCAF11,VCPIP1,RNF14,RNF139,CDKN2A,RNF114,TRIM41,TRAF7,SUZ12,UBR2,PTTG1,WDTC1,KLHL18,ANKIB1,MDM2,PSMA6,FBXL6,SIAH1,SOCS6,ANAPC7,TTC3,RNF19A,RNF169,SPSB3,PRPF19,RLIM,BIRC3,PSMA8,RNF25,CUL3,PSMB7,CDC23,ASB13,PSMB9,TRIM28,BTBD1,SOCS7,CDC16,PSMD3,UHRF2,RNF38,TRIM32,SMURF1,ZC3HC1,TRIP12,KLHL21,ZFP91,SHPRH,CDCA3,BRAP,CBLL1,UBE4A,WWP2,HERC3,RFWD3,FBXO3,PSMD2,KLHL20,HUWE1,LTN1,FEM1B,UBE3B,UBE2M,RNF5,DCAF6,TNFAIP3,RFFL,FBXO9,ANAPC2,PCGF1,FBXO21,KEAP1,BIRC5,KBTBD7,DTX4,UBE2C,DDB1,ANAPC4 |
| 7.714e-12 | -25.59 | EZH2 (enhancer of zeste 2 polycomb repressive complex 2 subunit) | protein interactions | 2146 | 279 | 91 | 17029 | 2761 |
POLA2,CCDC93,USP7,IMMT,PDCD6IP,DNMT3A,HNRNPAB,NOP2,SF3B1,SUZ12,CUL1,SNRPD3,SAFB2,PABPC4,SSR1,SF3B2,OIP5,CDKN2C,VAV1,MDM2,ATP2A2,AKAP8,CRY2,RPN2,CEP63,DNMT1,SRSF10,SNRNP200,RBX1,KAT7,EHMT1,MKI67,BRCA1,TRIM28,SRSF1,CHCHD3,MRPL2,ATP1A1,FUS,NCOA1,REEP4,FAM208A,HDAC2,GEMIN7,WSB2,EWSR1,PHB2,GADD45G,DNAAF5,DHX9,KLC1,ATP5F1B,EZH1,THRAP3,NPLOC4,WWP2,KIF5B,ERH,HUWE1,PPP1R8,KMT5A,EFTUD2,H2AFY,YBX1,FBL,LUC7L2,TK1,MAPKAPK3,ZMYND11,ILF3,PLEC,PKM,PCGF1,API5,SNRPA,HSPA1B,RPL36,EPRS,UPF1,EPOP,CDCA7L,PML,LRPPRC,DDX5,WDR76,SRSF3,YY1,RBBP4,SNRNP70,CDK2,ZC3HAV1 |
| 7.812e-12 | -25.58 | regulation of mitotic cell cycle phase transition | biological process | GO:1901990 | 422 | 118 | 17256 | 2622 |
ZNF207,FGFR1OP,UBE2E2,GPR132,KMT2E,DYNLL1,TPX2,CUL1,SIRT2,CCNB1,PRKACA,APP,FANCI,CDKN2C,PSMA6,PCNA,PSMD1,MDM2,NEK6,KIF14,CDKN1B,ECD,CEP63,CTDSP2,CARM1,DCTN1,PLK1,PLK3,BRD4,RBX1,PSMA8,BTG2,TAOK1,CUL3,PSMB7,MRNIP,CDC6,AURKB,BRCA1,CDC23,ANLN,SOX4,PSMB9,RAD51C,RPS27A,RBL1,PSMD8,PSMD3,NSMCE2,E2F4,XRCC3,CHEK2,VPS4A,TFDP2,GEN1,PSMC1,CSNK1D,TUBB,MAPRE1,CLSPN,PHB2,MECP2,CDT1,CENPF,DCTN2,CDK2AP2,HAUS4,BLM,PSMD9,CNOT11,RAB11A,HAUS2,CDC73,MAD2L2,CNOT3,RFWD3,RPA2,TFAP4,DTL,PSMD2,RB1,CCP110,PTEN,CENPJ,FBXO7,GTSE1,BRD7,BCL2,FBXL7,KNTC1,CNOT6L,TGFB1,PPP1R9B,ADAM17,PRKDC,PSMA1,PRMT2,PSMB3,HAUS8,PSMC4,CNOT9,PCM1,TFDP1,CDCA5,ODF2,E2F1,PML,SSNA1,CNOT6,PKD2,NDE1,ZNF830,UBE2C,CDK2,ESPL1,ANAPC4,DDB1,CDKN2A |
| 7.972e-12 | -25.56 | STEIN_ESRRA_TARGETS_UP | MSigDB lists | STEIN_ESRRA_TARGETS_UP | 353 | 103 | 17377 | 2626 |
MMACHC,IMMT,UGP2,SUCLG1,IVNS1ABP,RPS6KA1,MDH2,TMX4,NANS,TWF2,DUSP22,SDHA,ANKRD28,RAB21,DECR1,GOT2,THAP4,RAB35,MRPL34,CS,MECR,NFU1,AHCYL1,TRIM14,GM2A,TIMM50,SRPK2,PPIF,KIAA0040,IDH3A,CRNKL1,VDAC2,HTATIP2,SMC2,OGDH,PRPSAP1,PDHX,CHCHD3,TMEM184C,EIF3K,MRPL2,ACYP1,TIMM17A,QRSL1,MLYCD,COX5A,TRIM52,PPP2R2D,PFKP,KIF3B,COX5B,NDUFS1,MUT,ANXA6,ZNF768,B4GALT5,LETMD1,SLC25A12,CYCS,GMCL1,JMJD6,SIKE1,IFT27,RAPGEF6,NDUFS7,CFLAR,NDUFS4,EBP,SLC31A1,GSTK1,NDUFV1,PDCD10,NDUFS8,AFF1,PCYT2,MRPL11,MTX2,RNF5,IMPA2,NAGPA,CYTH1,NQO2,FAM50B,PCGF1,RBM38,MFN2,AKAP1,SDHB,NUCB1,ETS2,SLC38A7,QARS,STX18,SLC16A1,ACAT1,MDH1,ACADM,GPI,IDH3B,RNF14,RNF139,NUDT3,EGLN1 |
| 8.159e-12 | -25.53 | Cbx1 (chromobox 1) | protein interactions | 12412 | 150 | 59 | 17029 | 2761 |
ZNF445,SDC2,FLOT1,TOP2B,NSD3,ORC1,BRIX1,HDGFL2,CSNK1A1,RLF,RCOR3,CHD1,GNB2,MAD2L2,PHC2,RPA2,KDM2A,MTA1,BANF1,YBX1,AHDC1,MRPL48,ALDH18A1,GNAI2,ATP6V0D1,NIPSNAP1,UBQLN4,DDX24,RBX1,ZNF512,KAT7,MTA2,TEX10,EHMT1,MKI67,RPS24,RCOR1,CCDC71L,H2AFV,TRIM28,CHAF1A,ZMYM3,IWS1,DOT1L,SUPT16H,CBX3,UBTF,GNAS,BRWD1,RPS14,RBMX,BBX,TFDP1,BAZ1B,WDR76,FAM208A,PDCD11,HDAC2,ADNP2 |
| 8.335e-12 | -25.51 | GO_PROTEIN_TARGETING | MSigDB lists | GO_PROTEIN_TARGETING | 391 | 111 | 17377 | 2626 |
POLA2,TOMM20,NUP188,SYS1,MTX3,TSC2,RPLP2,ANK3,VTI1A,BECN1,RPAIN,RPL11,SSR1,RPL23A,SNUPN,TIMM23,ATG3,NUP107,TNPO2,F2R,GCC1,TIMM50,CDC37,SRP72,RPL29,SEC61B,RPL35,RAB7A,RPL38,NUP155,NUTF2,ICMT,RPS9,RPSA,OPTN,RPL37,TRAM2,HSPA4,TIMM13,CHMP4A,PEX5,SEC61A1,RPS27A,TIMM17A,RPS14,ARNTL,RPLP1,KPNA2,CHMP4B,FAU,MAPK1,SMURF1,RPS26,LONP2,PARD3,RPS15,RPS2,SEC61G,PHB2,RAE1,TRAK1,NUP54,NKD2,RPL15,RAB6A,VPS25,NUP205,LMNA,ATG4A,RPL17,KIF13B,FBXO7,ARL6IP1,TNPO3,RPL19,STAT3,MTX2,NUP85,PACS2,TMED2,NAGPA,TGFB1,TIMM8B,GCC2,PPP3CA,RPS10,RPL6,RPL8,RPS24,SSR2,PACS1,RAB3IP,MTX1,TOMM40,PTTG1IP,RPL27A,ZDHHC3,MAPK3,RPL36,MFN2,SCARB2,HGS,KPNA4,GOLGA4,KPNA1,RPL32,PML,NUP62,YWHAZ,TOB1,IPO4 |
| 8.469e-12 | -25.49 | GO_POSITIVE_REGULATION_OF_PROTEIN_CATABOLIC_PROCESS | MSigDB lists | GO_POSITIVE_REGULATION_OF_PROTEIN_CATABOLIC_PROCESS | 253 | 81 | 17377 | 2626 |
ATXN3,SUMO2,CUL1,CSNK2A1,SIRT2,UBQLN2,CCNB1,ANKIB1,BCAP31,FBXO22,USP5,MDM2,PSMD1,PSMA6,CDKN1B,ANAPC7,RNF19A,TIPARP,PLK3,PLK1,PSMA8,RAB7A,CUL3,PSMB7,EZR,CDC23,RAB1A,EDEM2,PSMB9,CDC16,RPS27A,PSMD8,AXIN1,NSMCE2,PSMD3,SOCS4,ADAM9,ZNF268,TRIM32,CLU,DVL1,SMURF1,PSMC1,OAZ1,CSNK1D,USP13,GGA1,GORASP1,DNAJB2,NKD2,CSNK1A1,PSMD9,PSEN1,RHBDD1,FBXO5,DDRGK1,PSMD2,RB1,PTEN,LPCAT1,SOCS5,TNFAIP3,GBA,PSMA1,ANAPC2,PTTG1IP,PSMB3,PSMC4,HSPBP1,KEAP1,CDC27,GOLGA2,NSF,OAZ2,RNF14,UBE2C,CD81,ESPL1,RNF139,ANAPC4,RNF114 |
| 8.755e-12 | -25.46 | protein export from nucleus | biological process | GO:0006611 | 143 | 55 | 17256 | 2622 |
RPS15,NDC1,NUP188,CDC40,SARNP,THOC1,SRSF6,RAE1,RBM8A,ALKBH5,NUP54,AGFG1,XPO7,NUP205,HNRNPA2B1,ANKLE1,NUP210,EIF4A3,SRSF4,NUP107,UPF2,NUP153,GLE1,CHTOP,AHCYL1,CPSF4,ZC3H3,NUP85,SEH1L,CHP1,SRSF11,TGFB1,EIF5A,FYTTD1,NXT1,POLR2D,RNPS1,SLBP,NUP155,NUTF2,SRSF5,DDX39A,SYMPK,RPSA,SRSF1,HHEX,TSC1,UPF1,NUP62,SRSF3,RRS1,SMURF1,NMD3,NUP58,AAAS |
| 9.006e-12 | -25.43 | GSE17974_2H_VS_72H_UNTREATED_IN_VITRO_CD4_TCELL_DN | MSigDB lists | GSE17974_2H_VS_72H_UNTREATED_IN_VITRO_CD4_TCELL_DN | 172 | 62 | 17377 | 2626 |
TCF12,COMMD10,GALK1,ANKRD27,NADSYN1,TMUB1,RHOC,ACAP1,JMJD6,PXMP2,EIF2AK4,ZADH2,GLRX3,COPG2,POLR3K,GFM2,FBXO22,ARL6IP6,MCTS1,SNRNP25,CCNA2,GSDMB,C4orf3,TBC1D22A,DUT,SRI,ZDHHC13,MDFIC,ORC3,DNMT1,MYO5A,DRAM2,RNASEH2C,MAPKAPK3,POLR3GL,GALK2,NDUFA7,CCNF,STYXL1,APPL1,CLNS1A,ASF1B,CHCHD3,KIF2A,PLD3,PRDX3,EIF2D,MAP4,MPV17,PRMT7,C4orf46,COX5A,HMGB2,DTD1,WDR76,TMEM101,TATDN1,COPS6,ZMIZ1,ANXA11,RHEBL1,NXT2 |
| 9.095e-12 | -25.42 | HIST1H3A (histone cluster 1 H3 family member a) | protein interactions | 8350 | 284 | 92 | 17029 | 2761 |
MBD1,ASH1L,DNMT3A,H2AFZ,MPHOSPH8,KDM4A,UBN1,FLYWCH2,RAC1,SMARCA4,NSD3,SIRT2,USP48,CHD1,KIFC1,RAD23B,KIF22,RNF169,CARM1,BRD4,HMGN4,EID1,AKT2,KAT7,EHMT1,DNAJC9,ATXN1,NUSAP1,CDCA2,AURKB,EDF1,PBRM1,KDM1B,MCM2,KMT2C,TRIM28,ASF1B,CHAF1A,SUPT16H,PAF1,BRD2,KIF18B,CHD3,TONSL,H2AFX,UHRF2,BAZ1B,HDAC2,SSRP1,RECQL,CMAS,SHPRH,MECP2,FLOT1,CDCA8,SMC6,KIF23,WDR5,RLF,CDC73,LMNA,MCM5,BANF1,PRC1,H2AFY,ANP32A,CTR9,CREB1,MORC3,NASP,KAT2A,ZNF512,PRKDC,MTA2,RCOR1,PCGF1,MEN1,KIF11,CBX3,ATAD2,PALB2,CDCA5,KMT2B,PRMT7,CABIN1,YWHAZ,WDR76,RBBP4,PARP10,IPO4,DDB1,EGLN1 |
| 9.207e-12 | -25.41 | GO_MITOCHONDRION_ORGANIZATION | MSigDB lists | GO_MITOCHONDRION_ORGANIZATION | 543 | 142 | 17377 | 2626 |
MTX3,NDUFB6,TMEM203,MRPS15,UQCR10,BECN1,MRPL19,PARK7,ATPAF1,TIMM23,ATG3,SIVA1,DNAAF2,TRMU,TXLNA,NDUFB9,CISD2,MRPL32,TIMM50,CDC37,BAK1,GABPA,ATG9A,HARS,SNRPB,MRPL12,MRPL43,MCL1,SLC25A5,FOXRED1,STOML2,TIMM13,MRPL27,OGT,MPV17,QRSL1,CLU,MRPL13,PFKP,SLC25A33,NDUFV2,MRPL9,MRPS2,PHB2,MEF2A,CYCS,NDUFS7,NDUFS4,ATG4A,MEX3C,RIMS3,FBXO7,BCL2,MRPL48,MRPL40,MRPL21,ZNF189,TIMM8B,NOA1,MRPL16,MTX1,TOMM40,PI4K2A,PPP3R1,MDH1,YWHAZ,WIPI2,MRPL3,CDKN2A,NDUFA5,IMMT,TOMM20,NDUFAF2,DYNLL1,MRPL39,BCL2L1,MOAP1,MRPL50,NRF1,MRPL34,MRPS27,TP53BP2,C8orf59,ATF2,HTRA2,PPIF,CRNKL1,NDUFA7,NDUFB1,POLG2,MRPS14,TAZ,CHCHD3,MRPL2,DAP3,HSPA4,MRPL55,CHCHD1,TIMM17A,NDUFA11,SMURF1,EYA2,GCLM,NDUFS1,MRPL42,MRPS26,ATG2B,GFM2,SLC25A36,RFWD3,NDUFV1,NDUFA2,GATC,SLC1A4,NDUFB4,ANXA5,MRPL54,ATG13,NDUFS8,MRPL11,STAT3,NDUFA3,MTX2,KAT2A,TMEM39A,TIMMDC1,TMEM126B,JTB,TUFM,HEBP2,MRPS10,RHOT1,RHOT2,CHCHD6,MARK2,MFN2,PRDX3,TFDP1,COX8A,E2F1,NDUFS5,YWHAH |
| 9.261e-12 | -25.41 | DDX17 (DEAD-box helicase 17) | protein interactions | 10521 | 158 | 61 | 17029 | 2761 |
CYLD,EWSR1,IVNS1ABP,TCF3,SUMO2,DHX9,CUL1,CSNK2A1,RBM4,APP,WWP2,RPA2,MDM2,PCNA,EIF4A3,MCM5,PIN1,UBA5,EFTUD2,TXLNA,CRY2,TARDBP,FBL,RBM15,CDC5L,CDC37,PLK1,EIF5A,AMPD2,STAU1,VHL,WBP2,RNPS1,CUL3,SREK1,BRCA1,PLEC,MCM2,PRPSAP1,MATR3,SF3A2,DHX15,ISG15,SRSF1,RPA1,XRCC5,DDX17,CAND1,SYNCRIP,DGCR8,QARS,HNRNPH3,ATXN2L,DDX5,FUS,SRSF3,SNRNP70,CDK2,CD81,HDAC2,BYSL |
| 9.269e-12 | -25.40 | YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_17 | MSigDB lists | YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_17 | 168 | 61 | 17377 | 2626 |
NDUFV2,GCLM,SMAP1,NDUFB6,MRPS15,PHB2,MDH2,PDAP1,UFC1,COPE,DCTN2,TMEM109,DLGAP4,STARD7,TWF2,POLR3K,VPS25,LMNA,FKBP1A,CAPN2,EIF4A3,INPP5A,ARPC5,MRPL34,EI24,PARL,PDCD2,RPN2,NDUFB9,BCAP29,CYB5R1,TCEA1,TALDO1,MRPL21,ALDH9A1,TMEM160,SLC39A9,DRAP1,PSMB7,PSMG1,ADSL,MRPL16,KRTCAP2,MRPS14,ARF4,XRCC5,SDHB,MRPL2,NAP1L1,TIMM13,DDOST,TMED10,PSMD8,CORO1C,NDUFA11,ACTB,COPS6,PTDSS1,SLC25A39,TUBB,FAF1 |
| 9.625e-12 | -25.37 | REACTOME_MRNA_SPLICING | MSigDB lists | REACTOME_MRNA_SPLICING | 102 | 44 | 17377 | 2626 |
CDC40,POLR2K,SF3B1,SRSF6,RBM8A,DHX9,SNRPD3,PCBP1,PAPOLA,GTF2F1,SF3B2,HNRNPA2B1,DNAJC8,SRSF4,EFTUD2,YBX1,CCAR1,PCBP2,HNRNPM,CSTF1,SRSF11,POLR2I,SNRNP200,POLR2L,POLR2G,SNRPB,HNRNPF,POLR2D,RNPS1,SRSF5,TXNL4A,SF3A2,SNRPA,POLR2A,SRSF1,DDX23,SUGP1,POLR2J,HNRNPR,RBMX,PRPF4,SRSF3,SNRPG,SNRNP70 |
| 9.977e-12 | -25.33 | HSD17B10 (hydroxysteroid 17-beta dehydrogenase 10) | protein interactions | 3028 | 259 | 86 | 17029 | 2761 |
KARS,PDCD6IP,TOMM20,HNRNPAB,MDH2,EIF3D,SUMO2,ACTR3,HNRNPUL2,RAC1,COPE,CUL1,GLUD1,FKBP2,SDHA,APP,PARK7,HNRNPA2B1,RAB8A,PSMD1,EIF4A3,GRSF1,HADHB,CS,AKR1B1,TARDBP,CHTOP,PDIA6,HTRA2,GPX4,PRPF19,COPS8,CCT2,CUL3,RNPS1,EZR,UBE2V1,PITPNB,OGDH,MCM2,TRIM28,PDHX,MAT2A,ALDH3B1,TMED10,CHD3,PSMD3,H2AFX,TRAF5,PSMC1,PPIB,NACA,TKT,RAB11A,BZW2,FKBP1A,HUWE1,MCM5,RTCB,NAA50,CTPS1,TAGLN2,NAP1L4,PABPC1,EEF1D,RHOA,SF3B6,PIP4K2C,TOMM40,CCT8,PSMC4,CAND1,XRCC5,ADSS,SEC31A,TPD52L2,NAP1L1,PRDX3,HNRNPH3,PGRMC1,ACAT1,MDH1,ATP5F1A,RUVBL2,HNRNPDL,FAF1 |
| 1.006e-11 | -25.32 | GSE22432_MULTIPOTENT_VS_COMMON_DC_PROGENITOR_UNTREATED_UP | MSigDB lists | GSE22432_MULTIPOTENT_VS_COMMON_DC_PROGENITOR_UNTREATED_UP | 189 | 66 | 17377 | 2626 |
SRM,IMMT,GNPNAT1,NOP2,MDH2,TMEM97,PCNA,NOL11,IARS,EIF4A3,NVL,PIN1,EXOSC1,NUP107,RPN2,CISD2,AHCYL1,PDIA6,LRRC59,NOL12,PPIF,ABHD11,NUTF2,ODC1,GFER,GEMIN5,HSPA4,NIP7,TBL3,RWDD4,KLHDC4,RRS1,SLC25A39,SLC25A33,NUP54,CHAC2,NUP205,PTPN2,RBM17,ERH,COQ4,FEM1B,GEMIN6,YBX1,GTF2H2,TMEM160,NUDC,PHF10,SIGMAR1,ILF3,UTP15,TSR2,TARS,BBS12,ADSS,EPRS,TPD52L2,MTHFD2,PRDX3,CEBPG,SRSF3,SPCS3,NDUFS5,ATP6V1C1,NAA20,PGAM1 |
| 1.006e-11 | -25.32 | GSE17721_POLYIC_VS_PAM3CSK4_1H_BMDC_UP | MSigDB lists | GSE17721_POLYIC_VS_PAM3CSK4_1H_BMDC_UP | 189 | 66 | 17377 | 2626 |
RAB14,SARNP,MRPS15,CXXC1,TSC22D3,PMS2,GYG1,INO80E,HCFC1R1,DAZAP2,EIF1B,BIRC2,MRPL50,NAPG,DUT,FIZ1,PARL,AKR1B1,CORO1A,EIF5,SENP1,ARL5A,SEH1L,ELOF1,NXT1,PTPN18,EID1,RBX1,SREK1,TOPORS,PSMB9,LUC7L,CBFB,TBC1D17,CHCHD1,PPM1G,ZMAT3,FUBP1,RECQL,DNAJC5,PHF23,GADD45G,CBLL1,SMC6,ARGLU1,PSEN1,TTF1,SMC3,BDH1,BTF3L4,FAM89B,MEA1,GLTP,CNN2,NDUFA3,LUC7L2,SMC4,ALDH9A1,PDPK1,ZMYM5,VKORC1,EIF4H,CBX3,SERF2,MFAP1,RNF114 |
| 1.058e-11 | -25.27 | GSE45837_WT_VS_GFI1_KO_PDC_DN | MSigDB lists | GSE45837_WT_VS_GFI1_KO_PDC_DN | 185 | 65 | 17377 | 2626 |
BCCIP,GMFG,ANXA6,PHB2,UQCR10,MUM1,TOR3A,ENSA,STARD7,UBE2Z,EBNA1BP2,NENF,TWF2,PSMD9,NDUFS7,ZNF428,SNRNP25,MZT2A,NDUFA2,THADA,NDUFB4,MCM5,ARF5,PIN1,PARL,AP2B1,AHCY,MRPL40,SRPK2,NIPSNAP1,VOPP1,CLPTM1,HEMK1,POLR2I,SEPT9,APH1A,KIAA0040,DRAP1,RPL6,HNRNPF,RFXANK,ADSL,NDUFA7,EDF1,MPG,NDRG3,RPS9,STOML2,HMGN2,EIF3K,GNA12,DAP3,PSMD8,FASTK,DBI,COX8A,AEN,COX5A,UQCRH,COPS6,IGBP1,MZT2B,C7orf26,PFKP,ANXA11 |
| 1.058e-11 | -25.27 | GO_POSITIVE_REGULATION_OF_CELLULAR_PROTEIN_CATABOLIC_PROCESS | MSigDB lists | GO_POSITIVE_REGULATION_OF_CELLULAR_PROTEIN_CATABOLIC_PROCESS | 185 | 65 | 17377 | 2626 |
SUMO2,CUL1,SIRT2,UBQLN2,CCNB1,ANKIB1,BCAP31,FBXO22,USP5,MDM2,PSMD1,PSMA6,ANAPC7,RNF19A,PLK1,PLK3,PSMA8,PSMB7,CUL3,EZR,CDC23,RAB1A,PSMB9,CDC16,RPS27A,PSMD8,PSMD3,NSMCE2,AXIN1,SOCS4,DVL1,CLU,SMURF1,PSMC1,CSNK1D,GORASP1,DNAJB2,NKD2,PSMD9,PSEN1,CSNK1A1,FBXO5,DDRGK1,PSMD2,RB1,PTEN,SOCS5,TNFAIP3,GBA,PSMA1,ANAPC2,PTTG1IP,PSMB3,PSMC4,HSPBP1,KEAP1,GOLGA2,CDC27,CD81,UBE2C,RNF14,RNF139,ESPL1,ANAPC4,RNF114 |
| 1.058e-11 | -25.27 | GSE20198_UNTREATED_VS_IFNA_TREATED_ACT_CD4_TCELL_DN | MSigDB lists | GSE20198_UNTREATED_VS_IFNA_TREATED_ACT_CD4_TCELL_DN | 185 | 65 | 17377 | 2626 |
ST13,WDYHV1,GPR89A,COPE,MON1B,AP3M2,AGFG1,NANS,OAT,SLC20A1,MRPL19,MIS12,CD320,ANKRD28,UBA5,SRI,TOP1MT,RBM15,SLC39A9,PLK3,POLR2G,NUP155,DNAJA1,UTP3,PSMB9,ARL5B,LUC7L,MAK16,MAFK,CORO1C,FBXL3,GEMIN7,C19orf53,MRPL42,DHPS,EYA1,SECISBP2,TMEM179B,CHKA,MCTS1,LYAR,SLC1A4,RBM34,DDX31,PCYT2,CITED2,RNF135,MRPL11,CSRP1,PRKDC,NQO2,METTL5,GTPBP4,MRPL16,DCTD,FAM133B,DAPK3,NMT2,HSPA1B,PDCD6,GOLGA7,TWSG1,PDLIM5,GPR89B,GCSH |
| 1.108e-11 | -25.23 | CHIANG_LIVER_CANCER_SUBCLASS_UNANNOTATED_DN | MSigDB lists | CHIANG_LIVER_CANCER_SUBCLASS_UNANNOTATED_DN | 181 | 64 | 17377 | 2626 |
CMAS,PRKAB1,TP53RK,MAPRE1,H2AFZ,COPA,MRPL42,SCAMP3,TMBIM4,C1orf112,MRPL39,RAE1,MAGED1,TPX2,CHCHD2,NDUFA4,ABCB10,SLC29A1,GFM2,MAD2L2,NUP205,DNAJB9,MCTS1,SEC11A,FARSA,PCNA,ATG3,DAD1,ATIC,MSH2,YBX1,RNASEH2A,OSTC,CITED2,PDIA6,ATP6V0D1,IMPA2,TMX1,CCT2,RHOA,RFC3,DPM1,SNX2,PBK,RAD51AP1,PSMG1,DNAJA1,CAPZA2,DCUN1D5,SLC25A5,ARPC1A,CLNS1A,NEU1,STOML2,XRCC5,ATP1A1,SEC61A1,STT3A,TAB2,PSMD8,DBI,CAB39,MRPL13,CCNB2 |
| 1.130e-11 | -25.21 | RPL31 (ribosomal protein L31) | protein interactions | 6160 | 151 | 59 | 17029 | 2761 |
RPS15,NIFK,RPS2,CYLD,EWSR1,RPLP2,TCF3,DHX9,MOGS,RPL15,CUL1,EBNA1BP2,APP,RPL11,RPL23A,CRKL,LYAR,DDX56,EIF4A3,PTEN,RPL17,AHSA1,RPL19,TARDBP,FTSJ3,HNRNPM,RPL35,RPS10,RPL6,TUFM,CUL3,ILF3,RPL8,RPL38,RPS24,BRCA1,MCM2,RPL27A,SLC25A5,RPS9,DHX15,RPSA,ASF1B,RPL36,CAND1,NAP1L1,HNRNPR,RPS27A,RPS14,RBMX,RPLP1,YWHAZ,COPS6,RRS1,CDK2,ARRB2,SMURF1,CD81,RPS26 |
| 1.239e-11 | -25.11 | GSE14415_INDUCED_VS_NATURAL_TREG_DN | MSigDB lists | GSE14415_INDUCED_VS_NATURAL_TREG_DN | 169 | 61 | 17377 | 2626 |
CHMP2A,COX5B,CLSPN,CENPF,TPX2,CDCA3,RRM1,CDCA8,KIF23,NUF2,KIF2C,PMF1,FKBP2,NCAPG,STMN1,PCBP1,TUBGCP2,SSR1,RBM17,RPN1,SMC3,CCNA2,MCM5,KIF14,TTC9C,KIF22,RBM3,CORO1A,LMAN1,MRPL21,SEH1L,TACC3,PDCL3,GINS1,NOL12,PLK1,PIGT,ASPM,PBK,KIF15,MKI67,CKAP2L,WDHD1,BRCA1,SMC2,MCM2,SHCBP1,API5,KIF11,ASF1B,HMGN2,NAP1L1,BIRC5,PRDX3,PSMD8,NEIL3,NRM,CEP55,KPNA2,GEN1,CCNB2 |
| 1.244e-11 | -25.11 | GSE35685_CD34POS_CD10NEG_CD62LPOS_VS_CD34POS_CD10POS_BONE_MARROW_UP | MSigDB lists | GSE35685_CD34POS_CD10NEG_CD62LPOS_VS_CD34POS_CD10POS_BONE_MARROW_UP | 194 | 67 | 17377 | 2626 |
UBL3,IVNS1ABP,PIGQ,MAGED1,UROD,RRAGC,GLUD1,USP48,IKBIP,MAPK14,LIN9,APLP2,MDM2,STRBP,GRSF1,SLC44A1,BRI3,SUCLG2,TTC3,KIF22,CORO1A,TALDO1,SPTSSA,CLN6,TMBIM1,PDCL3,GPX4,SAP30,LRBA,CADM1,TRIM28,PON2,HHEX,TRIM47,MID1IP1,AHNAK,CAB39,RMND5A,NCOR2,CMAS,MRPL42,ANKH,TKT,KIF23,GOLM1,CAPN2,FUT8,MSH2,ALDH9A1,EIF3L,MLEC,SIGMAR1,ASPM,DENND4C,PPP1R21,RPL6,HSPA1B,RPL36,ADSS,FBXO21,GNA12,NAP1L1,CAPN7,ACLY,YWHAH,GCSH,TMEM131 |
| 1.294e-11 | -25.07 | GNF2_CCNB2 | MSigDB lists | GNF2_CCNB2 | 55 | 30 | 17377 | 2626 |
FOXM1,ASPM,PBK,CENPF,PTTG1,CDCA3,RRM1,CDCA8,TPX2,RRM2,RACGAP1,NUSAP1,KIF2C,SMC2,MCM2,SHCBP1,KIF11,SPAG5,OIP5,PCNA,CCNA2,KIF18B,BIRC5,PRC1,H2AFX,HMGB2,UBE2C,CCNB2,ESPL1,SMC4 |
| 1.317e-11 | -25.05 | GSE30962_PRIMARY_VS_SECONDARY_ACUTE_LCMV_INF_CD8_TCELL_UP | MSigDB lists | GSE30962_PRIMARY_VS_SECONDARY_ACUTE_LCMV_INF_CD8_TCELL_UP | 190 | 66 | 17377 | 2626 |
LUZP1,TMEM97,NUF2,AP1B1,STMN1,MOAP1,CCNA2,SIVA1,XRCC2,KIF22,MND1,CKAP2L,RRM2,NUSAP1,CDC6,AURKB,BRCA1,SMC2,PKMYT1,CCNF,SHCBP1,ASF1B,WAS,KIF18B,CEP55,H2AFX,KPNA2,FKBP5,MCM10,PKP4,CLSPN,HJURP,EYA1,CENPF,VAV2,RRM1,CDCA3,DBF4,KIF23,NDUFA4,SDF2L1,SPAG5,FBXO5,MCM5,BDH1,GEMIN6,NDUFS8,TTLL12,C12orf75,GINS1,TK1,PSPC1,ASPM,SNRPA,AKAP1,MTHFD2,ETS2,POLE,BIRC5,NEIL3,DBI,CDCA5,C4orf46,HMGB2,CCNB2,ESPL1 |
| 1.339e-11 | -25.04 | SCHLOSSER_MYC_TARGETS_REPRESSED_BY_SERUM | MSigDB lists | SCHLOSSER_MYC_TARGETS_REPRESSED_BY_SERUM | 153 | 57 | 17377 | 2626 |
RMND5A,DNAJC2,TOMM20,TXN,NDUFB6,CHERP,DHX9,C5orf30,CYCS,OAT,DCUN1D4,APP,PNO1,TFAP4,NUP210,IARS,EIF4A3,ATP13A3,EI24,H2AFY,NUP153,PTGES3,PDIA6,TMX1,LDHB,CCT2,DEAF1,IDH3A,FBXO9,USP10,PSMG1,DCTD,API5,CCT8,SERP1,TARS,EIF3A,SRSF1,GLOD4,CBX3,ADSS,EPRS,FBXO21,MTHFD2,PFDN4,ZNF330,IARS2,SLC16A1,KPNA2,BTF3,YY1,NR2F2,PGAM1,ZBTB11,MRPL3,HDAC2,RNF114 |
| 1.373e-11 | -25.01 | UHRF2 (ubiquitin like with PHD and ring finger domains 2) | protein interactions | 115426 | 104 | 46 | 17029 | 2761 |
UBE2D3,USP7,DNMT3A,CHERP,SUZ12,BCL2L1,CCNB1,UBE2I,CDK11B,TWF2,LYN,CDC73,FANCI,TFAP4,RB1,PCNA,CCNA2,KDM2A,PIN1,DNMT1,LUC7L2,TRIM8,BTAF1,TLK1,ZNF574,ATXN1,RCOR1,KRAS,MCL1,BCLAF1,PBRM1,DIDO1,MPG,MBD3,CDK11A,RPA1,XRCC5,CDC16,CHD3,LUC7L3,UHRF2,E2F1,YY1,NR2F2,CDK2,SMAD4 |
| 1.389e-11 | -25.00 | GSE13484_UNSTIM_VS_YF17D_VACCINE_STIM_PBMC_UP | MSigDB lists | GSE13484_UNSTIM_VS_YF17D_VACCINE_STIM_PBMC_UP | 186 | 65 | 17377 | 2626 |
EXOC3,HECA,ST13,MRPS15,SF3B1,TWF2,CUTC,PARK7,SSR1,MOAP1,SEC11A,PPP6C,FBXW2,PARL,TTC3,RPN2,AQR,ADCY7,TRIM8,PBXIP1,ZBED5,USP22,ESYT1,NDUFB1,SHCBP1,SRSF1,SUPT16H,AMZ2,ANKZF1,DAP3,DDX42,RMND5A,ASAH1,NKRF,TOP2B,UBE4A,DNAJB1,MYO9B,MAN2B1,XPO7,AP3S1,TUBGCP2,ARF5,XPA,LTN1,SS18L1,SLC35A1,CSNK1G3,PREB,ABHD2,MFNG,SSR2,C1orf35,FBXO9,SEPT7,KDM3A,API5,ZDHHC3,XRCC5,RPA1,PFDN5,PCM1,HNRNPH3,ZDHHC7,SPCS3 |
| 1.389e-11 | -25.00 | GSE2405_0H_VS_9H_A_PHAGOCYTOPHILUM_STIM_NEUTROPHIL_DN | MSigDB lists | GSE2405_0H_VS_9H_A_PHAGOCYTOPHILUM_STIM_NEUTROPHIL_DN | 186 | 65 | 17377 | 2626 |
H2AFZ,TXN,HNRNPAB,NDUFB6,RPLP2,ACTR3,DAZAP2,STMN1,RPL11,RPL23A,PCNA,PSMA6,CHTOP,ATP6V1G1,RPL35,RFC3,CDC123,RPL38,MKI67,RRM2,NUTF2,DCUN1D5,RPS9,RPSA,EIF3H,RPL37,PPP2R5A,HINT1,RPS14,COX5A,KPNA2,ACTB,SNRPG,RPS26,OAZ1,TUBB,UBE2D3,RPS2,TKT,CHCHD2,ARF1,ETS1,NFATC3,RPL17,ARL6IP1,RPL19,YBX1,RPL22L1,LDHB,LDHA,RPL6,RPS10,PSMA1,EIF4G2,RPL27A,PRDX1,CYB5A,RBM38,RPL36,DDX5,YWHAZ,MRFAP1L1,SRSF3,RBBP4,NUDT3 |
| 1.389e-11 | -25.00 | GSE24634_TREG_VS_TCONV_POST_DAY5_IL4_CONVERSION_UP | MSigDB lists | GSE24634_TREG_VS_TCONV_POST_DAY5_IL4_CONVERSION_UP | 186 | 65 | 17377 | 2626 |
NUP188,UCK2,EBNA1BP2,BRIX1,PPP1R16B,POLR3K,MRPL19,CD320,OIP5,DUS4L,PPCDC,AP2B1,RNASEH2A,PLK1,PPIF,TDP1,IDH3A,MKI67,POLR2D,SLBP,DNAJC9,BRCA1,NDUFA7,ICMT,PSMB9,RFC2,MAK16,PRIM1,SUPT16H,PON2,TIMM13,NIP7,POLQ,SSRP1,DNAJC2,C19orf53,HJURP,RRP15,CDT1,CDCA3,DBF4,PXMP2,TTF1,CFLAR,ERH,GART,SUV39H2,BDH1,GEMIN6,KNTC1,ORC3,MRPL11,UBE2M,MYBL2,GTPBP4,NFATC2IP,DDX39A,SLCO4A1,EPRS,CCDC86,NEIL3,TBPL1,SLC16A1,RUVBL2,RBBP4 |
| 1.389e-11 | -25.00 | GSE3982_EFF_MEMORY_CD4_TCELL_VS_TH1_DN | MSigDB lists | GSE3982_EFF_MEMORY_CD4_TCELL_VS_TH1_DN | 186 | 65 | 17377 | 2626 |
H2AFZ,TAP1,TPX2,GLUD1,UBE2I,POLR3K,CREM,PA2G4,PSMD1,EIF4A3,EFCAB11,NSFL1C,AKR1B1,RNASEH2A,LMAN1,NAA35,NOL12,SLC39A9,MKLN1,IDH3A,MRPL12,RRM2,NUSAP1,BRCA1,CLNS1A,MID1IP1,CDCA4,PSMD3,TBL3,TUBB,NDUFV2,NDUFS1,NSMCE4A,PPP1R2,TOR3A,FLOT1,RRM1,KIF23,NDUFA4,BLM,SPAG5,FBXO5,C12orf10,PTEN,MCM5,TIMELESS,MRPL40,CYC1,HNRNPM,MAPKAPK3,EXOSC9,C9orf40,SDHB,SLCO4A1,TRIM26,CDC27,PFDN4,PRDX3,TWSG1,MFAP1,TFDP1,CEBPG,PRMT7,GPI,EHD4 |
| 1.439e-11 | -24.96 | PCNA (proliferating cell nuclear antigen) | protein interactions | 5111 | 299 | 95 | 17029 | 2761 |
MBD1,CYLD,GNPDA1,MDH2,MAGED1,ANK3,PMS2,CUL1,USP39,CCNB1,USP5,RAD23A,CDK5,FANCL,MDM2,PCNA,CCNA2,SIVA1,PPME1,PARPBP,PDS5B,ATF2,DNMT1,CCAR1,RFC3,E2F3,CUL3,MCL1,CDC6,BRCA1,RFC2,H2AFV,FANCE,DHX15,RPSA,CHAF1A,DDX17,DSN1,RAD18,GADD45B,WDR4,UHRF2,BAZ1B,FUS,UBE2D3,PPIB,EWSR1,CLSPN,SHPRH,CHTF18,CDT1,GADD45G,BABAM1,DHX9,FOXO3,CDC73,WDR48,LMNA,WWP2,WRNIP1,DTL,TFAP4,RPA2,SUB1,PDCD10,HUWE1,KMT5A,MSH2,TIMELESS,SLC27A4,YBX1,MSH6,CYFIP1,POLK,PRKDC,LDHA,USP10,UHRF1BP1,POLR2A,RPA1,XRCC5,SEC23IP,PLAA,POLE,CDC27,PRDX3,RUVBL2,TCOF1,GPI,CDK2,HEXA,PARP10,PGAM1,DDB1,CDKN2A |
| 1.490e-11 | -24.93 | metaphase plate congression | biological process | GO:0051310 | 55 | 30 | 17256 | 2622 |
CHMP2A,PSRC1,PDCD6IP,CDT1,CENPF,CDCA8,CUL3,NUF2,KIF2C,CCNB1,CHMP2B,CDC23,SPDL1,BECN1,RAB11A,MIS12,KIFC1,KIF18A,CHMP4A,KIF14,CEP55,CDCA5,FAM83D,NUP62,KIF22,CHMP4B,VPS4A,RRS1,CHMP7,SEH1L |
| 1.527e-11 | -24.90 | GSE5542_IFNG_VS_IFNA_TREATED_EPITHELIAL_CELLS_24H_UP | MSigDB lists | GSE5542_IFNG_VS_IFNA_TREATED_EPITHELIAL_CELLS_24H_UP | 178 | 63 | 17377 | 2626 |
ZNF207,RHOG,CMAS,SKA3,PKP4,TRIP12,CXXC1,ZFP91,RAF1,PMS2,AGPAT3,NIPA2,AGFG1,NANS,GYG1,TMEM165,KCMF1,MYEF2,NUP205,MIS12,STARD9,ERH,LRRC8D,UCHL5,UBA5,GTSE1,KIFAP3,CYC1,MCPH1,STRAP,FYTTD1,ADAM17,RFC3,HMGN5,LAP3,AACS,NUDT4,LDHA,MYBL2,ILF3,CCDC34,LNX2,DNAJC9,VDAC1,CCNF,ARPC1A,PHF6,SCARB2,RAD51C,SEPT1,CDC27,CORO1C,PPM1G,STX18,COX8A,SLC16A1,CNOT6,SMPD4,NDE1,USP11,REEP4,HIPK3,DDB1 |
| 1.532e-11 | -24.90 | RPL11 (ribosomal protein L11) | protein interactions | 6135 | 187 | 68 | 17029 | 2761 |
CYLD,NOP2,RPLP2,RBM8A,CUL1,EBNA1BP2,BRIX1,APP,PAIP2,RPL23A,KRR1,PA2G4,MDM2,TARDBP,RPL35,VHL,MRPL12,RPL38,CUL3,BRCA1,MCM2,SLC25A5,RPS9,RPSA,RPS27A,RPS14,RPLP1,FUS,BTF3,COPS6,RRS1,FAU,ARRB2,RPS26,NIFK,RPS15,RPS2,RPL15,CDC73,TUBGCP2,LMNA,TIGAR,RPL17,AHSA1,RPL19,POLR1B,FBL,STAT3,PABPC1,HNRNPM,DDX24,RPL8,ILF3,TUFM,RPL6,RPS10,RPS24,MRPS10,RPL27A,CAND1,RPL36,NAP1L1,UPF1,RPL32,PML,CD81,CDK2,CDKN2A |
| 1.540e-11 | -24.90 | TOP1 (DNA topoisomerase I) | protein interactions | 7150 | 191 | 69 | 17029 | 2761 |
COX15,NOP2,NF1,SF3B1,CUL1,CSNK2A1,UBE2I,APP,HNRNPA2B1,PA2G4,MDM2,PCNA,DUS4L,TARDBP,CDC5L,SRPK2,TDP1,SNRNP200,MKI67,CUL3,TOPORS,CDC6,BRCA1,PBRM1,VDAC1,BTBD1,SRSF1,SUPT16H,DDX17,MAP3K4,JAK1,HNRNPR,RBL1,RPS14,TRIM32,SNRPG,H3F3A,CASP6,CDT1,DHX9,TOP2B,CDC73,LMNA,IRF4,MCM5,EFTUD2,MSH2,H2AFY,GEMIN4,FBL,HNRNPM,SRSF11,SF3B6,ARID1A,SYMPK,CAND1,DDX23,XRCC5,UTP20,TSC1,TRIM26,FNTA,RBM25,PALB2,ZRANB2,TCOF1,SNRNP70,CDK2,CDKN2A |
| 1.567e-11 | -24.88 | chromatin | cellular component | GO:0000785 | 526 | 136 | 18223 | 2701 |
MAX,H2AFZ,KMT2E,CSNK2A1,SIRT2,PARK7,MBD4,USF1,PARPBP,PDS5B,KIF22,MCMBP,SMARCE1,DNMT1,PLK1,BAZ2A,GABPA,RAD51AP1,WDR82,PBRM1,MCM2,ASF1B,CHAF1A,BRMS1,SMAD2,CHD3,E2F4,BAZ1B,ACTB,SLF1,SINHCAF,HDAC2,CENPF,DHX9,MEF2A,TOP2B,ASXL2,ARID1B,YY1AP1,RB1,SMC3,MBD2,BUD31,CTR9,TIMELESS,ICE2,TNRC18,HP1BP3,PHF10,ETV3,MTA2,LDB1,ARID1A,KDM3A,APPL1,HMGN2,NSMF,SETD3,RBMX,CDCA5,APPL2,RUVBL2,YY1,RBBP4,CDKN2A,SMARCD1,TCF12,CHMP2A,DNMT3A,MPHOSPH8,SUZ12,UBR2,MAGED1,SMARCA4,INO80E,MXD1,PHC2,SAP130,OIP5,AHCTF1,KMT5C,UCHL5,TARDBP,HTRA2,KDM3B,HMGN4,WBP2,NFATC2,MEF2D,KDM1B,H2AFV,MBD3,TRIM28,RBL1,STAT6,STAT1,UHRF2,H2AFX,ANP32E,BEND3,NCOA1,H3F3A,SMAD4,NCOR2,MECP2,SHPRH,TCF3,HMGN3,PAWR,CAPN2,RPA2,IRF4,SUV39H2,H2AFY,SS18L1,CREB1,CITED2,STAT3,MSH6,TELO2,HMGN1,HMGN5,NASP,KAT2A,POLR3GL,MEN1,CBX3,LEMD2,UPF1,PML,E2F1,HMGB2,CENPT,CHMP7,SLF2,IPO4 |
| 1.577e-11 | -24.87 | NUYTTEN_NIPP1_TARGETS_DN | MSigDB lists | NUYTTEN_NIPP1_TARGETS_DN | 799 | 191 | 17377 | 2626 |
TMED7,TMEM184B,TMEM203,TMEM41B,FAM129A,XIAP,GLUD1,TGOLN2,SEC16A,SLC20A1,ELMOD2,CMTM6,ATPAF1,PAPOLA,KRR1,CDKN2C,NUP210,DPYSL2,ZNF639,IL6ST,SLC44A1,PHTF1,TTC9C,RAB4A,RAD23B,ATP13A3,AP2B1,PLCL2,RYBP,SP3,ORAI2,TRIM8,OSBP2,PBXIP1,APH1A,MKI67,RRM2,GALNT7,MCFD2,ANLN,PRPSAP1,MAK16,ARF4,PLEKHF2,NECAP2,AHNAK,MID1IP1,BRWD1,TMED10,ZNF367,DHTKD1,ADAM9,ACTB,GALNT10,FBXL3,CHPT1,NMD3,SVIP,STARD3NL,FUBP1,WSB2,SEPHS2,SCOC,CLSPN,B4GALT1,DOCK11,LRRC14,NFATC3,UBE2Q2,KLHL5,ZNF326,CAPZA1,FAM89B,RBM3,ZRANB1,GNAI2,SLC12A2,N4BP2,PABPC1,VOPP1,EIF5A,RB1CC1,NUDT4,ERLIN1,ACSL3,RDH10,KCTD20,ARID1A,CAPZA2,PTTG1IP,EIF4G2,NMT2,GNAS,OSBPL11,GALNT2,CCDC86,ORMDL2,GOLGA2,NSF,PRPS2,SLC16A1,SLAIN1,TMEM106C,TOMM20,TRERF1,FOXM1,CAST,MAGED1,TMEM97,CREBL2,SLC35B2,TCF19,KTN1,MXD1,ARL6IP6,PHC2,ZNF473,ZNF302,ATP2A2,CCDC50,PPP6C,CYB5R1,F2R,ATP6V1G1,MND1,BRD4,POLR2L,HMGN4,MAP4K4,SMU1,CUL3,LRRC8A,DNAJA1,H2AFV,ERC1,KIF2A,RAD51C,SEC61A1,SURF4,CERS6,H2AFX,SEL1L,LMBR1,ANP32E,PDXK,NCOA1,REEP4,ABCA1,SLC25A39,TSPAN5,TCF3,CDK2AP2,SIKE1,AKT1S1,FBXO5,PDCD10,CWC27,HUWE1,PPP1R8,DCP1A,H2AFY,ANP32A,ATG13,MAP3K14,SGCB,UBE2M,IMPA2,TGFB1,NIPAL3,JMJD4,NUDT8,TACC1,TMEM126B,PRMT2,DDX39A,ARSK,INF2,RAB18,TPD52L2,FBXO21,KEAP1,MAGT1,PRDX3,ACOX1,MAPK6,PKD2,HMGB2,WDR76,NR2F2,THAP5,ESYT2 |
| 1.602e-11 | -24.86 | GO_MITOCHONDRIAL_PART | MSigDB lists | GO_MITOCHONDRIAL_PART | 852 | 201 | 17377 | 2626 |
COX15,LYRM4,MTX3,NDUFB6,MRPS15,UQCR10,MCCC1,GLUD1,ABCB10,OAT,BECN1,MRPL19,PARK7,SLC25A37,BCAT2,PRNP,TIMM23,GOT2,SLC44A1,HADHB,SUCLG2,NDUFB9,CISD2,LRRC59,MRPL32,TIMM50,BAK1,MRPL12,MRPL43,SLC25A22,MCL1,BRCA1,SLC25A5,FOXRED1,STOML2,TIMM13,PRDX5,MRPL27,IARS2,MPV17,MLYCD,DHTKD1,COX5A,UQCRH,CLU,RNASEL,MRPL13,SLC25A33,COX5B,NDUFV2,MRPL9,MUT,MRPS2,PHB2,NDUFA4,COX4I1,CYCS,PSEN1,NDUFS7,NDUFS4,BDH1,BCL2,CYC1,MRPL48,MRPL40,ACAD8,ALDH18A1,MRPL21,NSUN4,NIPSNAP1,CARS2,TIMM8B,DDX28,NOA1,PGS1,ACSL3,MRPL16,MTX1,TOMM40,MPG,SFXN5,CYB5A,AKAP1,CAT,SDHB,MTHFD2,QARS,COX7A2L,PDSS2,MRPL3,ACSF2,NDUFA5,KARS,IMMT,ATXN3,TOMM20,SUCLG1,NDUFAF2,MRPL39,RAF1,MDH2,BCL2L1,SLC25A44,SNN,LYN,SDHA,MOAP1,CSDE1,MRPL50,FLAD1,PDK2,DECR1,SHC1,GRSF1,CS,MRPL34,MRPS27,PARL,MAVS,APOOL,TOP1MT,ATF2,TMEM14C,HTRA2,ACSL5,PPIF,COQ10B,IDH3A,CPOX,VDAC2,NLN,NDUFA7,OGDH,VDAC1,NDUFB1,TAZ,POLG2,MRPS14,GFER,PDHX,CHCHD3,ANKZF1,MRPL2,DAP3,MRPL55,TIMM17A,TOMM6,CHCHD1,FASTK,NDUFA11,PPA2,PITRM1,SLC25A39,NDUFS1,CDS2,MRPL42,MRPS26,SLC25A12,LETMD1,SLC25A43,GFM2,SLC25A36,GSTK1,NDUFV1,COQ4,NDUFA2,NDUFB4,CRAT,MRPL54,NDUFS8,CREB1,MRPL11,NDUFA3,STAT3,MTX2,RNF5,SLC25A1,TIMMDC1,TMEM126B,MRS2,ABCF2,TUFM,MRPS10,RHOT1,GUF1,RHOT2,HAGH,CHCHD6,SH3GLB1,MFN2,PRDX3,PARG,LRPPRC,COX8A,ACAT1,SLC25A19,ACADM,NDUFS5,IDH3B,GCSH,HIGD2A |
| 1.621e-11 | -24.85 | protein catabolic process | biological process | GO:0030163 | 640 | 161 | 17256 | 2622 |
PDCD6IP,CUL1,UBE2Z,NHLRC3,SIRT2,UBQLN2,CCNB1,UBE2I,USP48,BIRC2,RNF103,FBXO22,PCYOX1L,PSMD1,RAD23B,AP2B1,PCBP2,USP34,PLK1,RBX1,TOPORS,USP22,AURKB,CCNF,USP21,RPS27A,PSMD8,AXIN1,ATE1,ARRDC1,CHEK2,CLU,VPS4A,KLHL42,FBXL3,CLN3,ARRB2,NGLY1,PSMC1,LONP2,UBE2D3,RMND5A,TMUB1,UBXN1,KCTD17,ZNRF3,PSMD9,VPS25,RHBDD1,NPLOC4,DTL,RNF121,ZNRF2,FBXO7,FBXL7,ZRANB1,LRSAM1,ERLIN1,MAN1B1,PSMA1,USP10,UBE4B,SYVN1,ARMC8,PSMB3,ISG15,PSMC4,DERL1,CDC27,KLHL15,SIAH2,DCAF11,USP32,CTSA,ECPAS,RNF139,USP7,ATXN3,CYLD,UBR2,PTTG1,RAD23A,USP5,UBXN2A,MDM2,PSMA6,SIAH1,MTA1,UCHL5,KIF14,NSFL1C,SOCS6,ANAPC7,TTC3,CLN6,SPSB3,HTRA2,RLIM,PRPF19,SEC61B,PSMA8,PPT1,RAB7A,PSMB7,CUL3,CDC23,EDEM2,TOLLIP,PSMB9,USP36,BTBD1,ANKZF1,DNAJC10,IDE,CDC16,UBXN2B,PSMD3,ARNTL,SEL1L,RNF38,CHMP4B,TRIM32,USP11,SMURF1,AP2S1,USP13,TRIP12,MANBA,UBE4A,SDF2L1,CSNK1A1,DNAJB9,WWP2,CAPN2,PSMD2,CTSS,KLHL20,LTN1,GTSE1,FBXL19,LYPLA2,RNF5,TNFAIP3,USP42,RFFL,FBXO9,ANAPC2,WDR81,CTSL,FBXO21,SGSH,KEAP1,PLAA,PML,PPP1R11,USP20,WDR91,UBE2C,ANAPC4,FAF1,DDB1 |
| 1.623e-11 | -24.84 | CROONQUIST_IL6_DEPRIVATION_DN | MSigDB lists | CROONQUIST_IL6_DEPRIVATION_DN | 96 | 42 | 17377 | 2626 |
GALK1,FOXM1,PTTG1,TPX2,PTP4A3,KIF2C,CCNB1,STMN1,FANCI,SPAG5,KIFC1,OIP5,PCNA,CCNA2,KIF14,DUT,KIF22,KNTC1,SMC4,GINS1,PLK1,RFC3,TK1,NASP,MYBL2,MKI67,RRM2,ITM2A,CDC6,AURKB,BRCA1,SMC2,MCM2,CCNF,KIF11,CHAF1A,ABHD5,ANP32E,KPNA2,HMGB2,UBE2C,CCNB2 |
| 1.634e-11 | -24.84 | MARTENS_TRETINOIN_RESPONSE_DN | MSigDB lists | MARTENS_TRETINOIN_RESPONSE_DN | 726 | 177 | 17377 | 2626 |
SRM,PPCS,NF1,FKBP2,SLC20A1,ABHD14A,TRIM65,RPL23A,PA2G4,PCNA,ATG3,DNAAF2,POP7,ZNF200,EIF5,DRAM2,PLK1,METTL1,MRPL12,TMEM216,HNRNPF,RRM2,UTP3,SOX4,CLNS1A,STOML2,RPL37,TIMM13,MID1IP1,NIP7,RPS27A,RPS14,PRDX5,ATXN2L,COPS6,RRS1,NGLY1,ZNF598,PDCD4,PTOV1,PPIB,PRPF38B,DHPS,PHB2,PHF23,ADO,RPL15,CHCHD2,COX4I1,CYCS,FAM136A,ZNF79,LYRM2,MYL6B,LRRC14,TMEM179B,TFAP4,DDX56,MLX,FAM89B,ORAI1,YBX1,RBM3,GEMIN4,MRPL40,MAML1,PABPC1,EIF5A,TIMM8B,PHF10,SIGMAR1,TSPAN31,RPS10,RPS24,MTX1,MATR3,HMGN2,RPL36,RBMX,CHMP2A,GLT8D1,MMACHC,TRIM41,TP53RK,UGP2,SLC35B2,HCFC1R1,PCBP1,C19orf48,STMN1,RPL11,RAD23A,HNRNPA2B1,NUDT19,FLAD1,FARSA,CCNA2,CD3EAP,UCHL5,DUT,MRPL34,PDCD2,TARDBP,CABLES2,ZNF770,CDKN2AIP,RPL29,NXT1,RPL35,POLR2L,HPDL,DRAP1,TIGD5,CIRBP,FRAT2,KIAA1586,PKMYT1,MBD3,TRIM28,RPS9,EIF3G,RPSA,MAT2A,SRSF1,MRPL2,CHMP4A,HINT1,HAGHL,NDUFA11,H2AFX,SPRYD4,H3F3A,CSNK1D,MIF4GD,ANKRD13D,SRSF6,CDT1,BABAM1,LETMD1,FBXO5,RFWD3,ZBTB45,RPL17,NAA50,RPL19,NAP1L4,CENPM,CITED2,MRPL11,HNRNPM,RNF5,LDHB,RBM15B,TELO2,HMGN1,TMEM126B,DENND4C,TUFM,TBRG4,FADD,CBX3,KEAP1,RPL32,BIRC5,GPS2,MFAP1,HNRNPH3,E2F1,DDX5,SSNA1,NR2F2,IDH3B,PURA,THAP5,HIGD2A,GPATCH4,SNAPIN |
| 1.661e-11 | -24.82 | SMURF1 (SMAD specific E3 ubiquitin protein ligase 1) | protein interactions | 57154 | 397 | 117 | 17029 | 2761 |
ATXN3,HNRNPAB,TRIP10,IVNS1ABP,CXXC1,SF3B1,UBQLN2,SNRPD3,PCBP1,APP,USP5,RAD23A,SF3B2,HNRNPA2B1,MDM2,ETV6,SRSF4,MRPS27,AP2B1,MAVS,PDIA6,STRAP,CCAR1,CFL1,TIMM50,DCTN1,ELOF1,CCT2,VHL,SNRPB,CIRBP,HNRNPF,UBE2V1,ZFAND5,SLC25A5,FKBP3,TRIM28,RPS9,MAT2A,EIF3H,CLNS1A,EIF3A,SRSF1,PPP2CA,UBTF,SMAD2,JAK1,GRIPAP1,RPS27A,RPS14,STK38,AXIN1,STAT1,OGT,ACTB,ROCK1,SMAD1,SMURF1,TRAF5,SMAD4,CSNK1D,TUBB,UBE2D3,C9orf78,RPS15,CDC40,ANKRD13D,ANXA6,SCYL1,UBXN1,CCM2,DCTN2,DHX9,EPN1,THRAP3,YY1AP1,LMNA,RTKN,RBM17,FBXO3,PSMD2,SUB1,RPL17,CAPZA1,YBX1,TTC17,UBE2M,EEF1D,SPTAN1,LDHB,RHOA,LONRF3,RPS10,TUFM,RPS24,BCLAF1,SRSF5,RIT1,KIF11,CCT8,PICALM,MARK2,SNRPA,ARHGAP15,POLR2A,HSPA1B,PSMC4,XRCC5,FBXO21,SYNCRIP,ODF2,LRPPRC,CCDC69,DDX5,ZRANB2,BYSL,RNF114 |
| 1.719e-11 | -24.79 | GSE15930_NAIVE_VS_24H_IN_VITRO_STIM_CD8_TCELL_DN | MSigDB lists | GSE15930_NAIVE_VS_24H_IN_VITRO_STIM_CD8_TCELL_DN | 191 | 66 | 17377 | 2626 |
SRM,NOP2,CHERP,MOGS,OLA1,TMEM97,POMP,INO80E,FKBP2,POLR3K,NUDT19,DECR1,NVL,SIVA1,PDS5B,PDCD2,RPF2,RPRD1B,TACC3,CARM1,ELOF1,POLR2L,RAD51AP1,MKI67,NUSAP1,BRCA1,MCM2,ANLN,RFC2,MRPL2,LUC7L3,CRCP,GCLM,GALK1,PDAP1,RRM1,KIF23,HAUS4,JMJD6,IFT27,SPR,RPN1,IRF4,CLIC4,MCM5,ALDH18A1,NUP85,PPA1,HDHD2,MTX2,PRIM2,TSPAN31,MRPS10,RHOT1,TPD52L2,SLC19A1,MTHFD2,CDKN2AIPNL,BIRC5,DCK,RBPJ,NDUFS5,PGAM1,HRAS,GCSH,DDX52 |
| 1.719e-11 | -24.79 | GSE21360_SECONDARY_VS_TERTIARY_MEMORY_CD8_TCELL_UP | MSigDB lists | GSE21360_SECONDARY_VS_TERTIARY_MEMORY_CD8_TCELL_UP | 191 | 66 | 17377 | 2626 |
MMACHC,NUP188,MRPL39,ACTR3,UROD,PLAGL2,NIT2,C2orf49,PARK7,SF3B2,CALM2,CD3EAP,GOT2,KIF14,DNAAF2,POP7,CS,INTS12,HTRA2,PRPF19,ORAI2,CPOX,MKI67,MRPL12,SMC2,UTP3,PKMYT1,CDC23,GINS4,PRIM1,IDE,HSPB11,UQCRH,ACTB,ATF6,REEP4,CCDC59,RAE1,IFT27,TMEM165,RMI1,NDUFS7,MRPL48,MRPL11,SLC12A2,MTX2,HNRNPM,TIMM8B,TK1,TSTA3,TUFM,JTB,USP10,TBRG4,BMS1,EXOSC9,MRPL16,MTX1,TOMM40,CCT8,SDHB,PLAA,SNAP29,PIAS2,COX8A,GPI |
| 1.735e-11 | -24.78 | THEILGAARD_NEUTROPHIL_AT_SKIN_WOUND_DN | MSigDB lists | THEILGAARD_NEUTROPHIL_AT_SKIN_WOUND_DN | 221 | 73 | 17377 | 2626 |
FEZ2,ADAM10,UBN1,TSC22D3,RPS6KA1,RAF1,CDIPT,TWF2,GNB2,CPNE3,MBD4,PHC2,SRSF4,NUP153,CORO1A,ARID4A,SRPK2,SELPLG,HTATIP2,ARHGDIB,STX16,SRSF1,HHEX,WAS,JAK1,STAT6,STK38,OGT,RBMS1,ROCK1,NCOA1,OAZ1,ANXA11,COX5B,PPP1R12A,DHX9,TKT,KLC1,CDK13,MYO9B,RGS2,FKBP1A,ADD3,ARHGEF1,TNPO3,CITED2,GNAI2,CAMK2G,TGFB1,CYTH1,MAPKAPK3,RABIF,PRMT2,EIF4G2,PDE3B,MARK2,FADD,MAPK3,DDX23,XRCC5,GNAS,MTMR3,SLC19A1,UPF1,POLR2J,PRDX3,SNAP23,ACLY,TBPL1,HMGB2,YY1,MAP3K5,TOB1 |
| 1.786e-11 | -24.75 | Vesicle-mediated transport | REACTOME pathways | R-HSA-5653656 | 650 | 172 | 10287 | 1696 |
RAB14,TMED7,COPA,TSC2,TGOLN2,AGFG1,KIF2C,UBQLN2,SEC16A,MAP1LC3B,RIC1,KIFC1,CALM2,NAPG,RAB8A,RAB35,RAB4A,AP1M1,DNM2,AP2B1,KIF22,TFG,COPS8,TRAPPC13,USO1,RHOBTB3,TMEM115,AKT2,KIF15,MCFD2,STX16,RAB5B,ARF4,OPTN,NECAP2,MAN2A2,TBC1D17,KIF18B,TMED10,RPS27A,MIA2,VPS4A,COPS6,ARRB2,C2CD5,HSPH1,SCOC,GORASP1,GGA1,CCZ1,EPN1,KLC1,KIF23,RACGAP1,TMED3,RAB6A,VPS25,COPG2,COPB2,GNS,CD59,ARPC5,SNX18,RINL,KIF13B,KIFAP3,PPP6R1,TMED2,APOL1,KDELR1,PREB,FTL,GCC2,CYTH1,TRAPPC9,ADRB2,ARPC1A,GOSR1,SEC31A,SCARB2,TSC1,GOLGA4,GALNT2,GOLGA2,NSF,SNAP23,EXOC4,YWHAZ,PPP6R3,ALS2,EXOC3,PRKAB1,ANKRD27,CHMP2A,SYS1,REPS2,TRIP10,RAB11B,DYNLL1,ACTR3,COPE,RAC1,ANK3,VTI1A,MON1B,TBC1D13,AP1B1,STAM,APP,REPS1,ANKRD28,RAB21,TBC1D14,PPP6C,CLTB,LMAN1,NAA35,GCC1,DVL2,DCTN1,RAB7A,BICD2,CHMP2B,RAB1A,AP4E1,KIF2A,CHMP4A,SURF4,AP1S1,CHMP4B,SCARB1,AP2S1,CSNK1D,DYNC1LI2,KIF3B,GOLIM4,DCTN2,VPS45,ARFIP2,AGPAT3,ARF1,GGA2,AP3S1,RAB11A,TFRC,PIP5K1C,MAN1A1,KIF5B,GRK2,SEC24C,ARF5,COPS7B,MYO5A,SPTAN1,SNX2,DENND1B,DENND4C,COG1,RAB3IP,KIF11,PICALM,RAB18,HGS,KIF18A,SEC23IP,SNAP29,CCZ1B,STX18,CHMP7,YWHAH,RAB3IL1,SNAPIN |
| 1.819e-11 | -24.73 | GSE2770_IL4_ACT_VS_ACT_CD4_TCELL_2H_UP | MSigDB lists | GSE2770_IL4_ACT_VS_ACT_CD4_TCELL_2H_UP | 187 | 65 | 17377 | 2626 |
WDR13,NIT2,UBQLN2,MAPK14,STAM,GNB2,PARK7,RALB,SH3BP1,MRPL34,FBXW2,NDUFB9,RP2,MAVS,F2R,GM2A,ELOF1,MAPRE2,SLBP,ARHGDIB,NFATC2,GALNT7,PEF1,ABHD5,MAP3K4,SUGP1,MRPL27,RWDD4,AP2S1,PPIB,CDS2,MANBA,DHX9,SUMF1,NDUFA4,HDDC2,EBP,GTPBP3,RFWD3,COPS7B,MRPL11,CAMK2G,CARS2,TMEM160,VOPP1,ZFP64,FAM49B,GUK1,PPP1R21,GUF1,ORMDL2,PDLIM1,NSF,PRPS2,COX8A,ACLY,C4orf46,CTSA,SLAIN1,GPI,NDUFS5,NANP,NAA20,TOB1,DEF6 |
| 1.819e-11 | -24.73 | GSE12845_IGD_NEG_BLOOD_VS_DARKZONE_GC_TONSIL_BCELL_DN | MSigDB lists | GSE12845_IGD_NEG_BLOOD_VS_DARKZONE_GC_TONSIL_BCELL_DN | 187 | 65 | 17377 | 2626 |
RHOG,RPS6KA1,ACTR3,MON1B,LAGE3,FARSA,RBM23,RABGAP1L,CHTOP,CTDSP2,CLCN3,HNRNPF,VDAC2,EZR,NUTF2,RFC2,DNAJC10,CDCA4,CHD3,U2SURP,PPM1G,SCARB1,PDCD11,PSMC1,OAZ1,FUBP1,RMND5A,DEPDC1,PHB2,CERK,PMF1,PRPF39,IFT27,MYL6B,RMI1,RAB11A,RGS1,CHKA,MCM5,MSH2,YBX1,HNRNPM,SPTAN1,RPRD1A,HMGN1,RBM42,NASP,PRKDC,TEX10,USP10,COMMD4,EIF4H,ABCF1,FAS,POLE,SERF2,TFDP1,COX8A,APPL2,MDH1,ZMIZ1,MYO9A,RUFY3,RBBP4,DDX52 |
| 1.841e-11 | -24.72 | RPSA (ribosomal protein SA) | protein interactions | 3921 | 220 | 76 | 17029 | 2761 |
KARS,CYLD,RPLP2,CHERP,SF3B1,DYNLL1,RBM8A,LAGE3,CUL1,NENF,ZNF121,RPL11,RPL23A,SF3B2,KRR1,PRNP,CALM2,PCNA,TARDBP,SRSF10,RPL29,RPL35,VHL,VDAC2,RPL38,BRCA1,MCM2,SLC25A5,RPS9,DHX57,HSPA4,RPS27A,RPS14,U2SURP,RPLP1,RRS1,FAU,ZBTB11,RPS26,POT1,DYNC1LI2,ZNF146,RPS15,EWSR1,RPS2,ZNF768,ANKH,DHX9,RPL15,CDC73,PNO1,KRI1,RPN1,RPL17,ZNF746,ZNF335,YBX1,ABCD1,RPL19,PABPC1,HNRNPM,RPL8,ZNF574,RPL6,RPS10,RPS24,BMS1,RPL27A,CAND1,RPL36,ZNF777,RPL32,SYNCRIP,RBMX,WDR76,RNF114 |
| 1.917e-11 | -24.68 | GSE12845_IGD_NEG_BLOOD_VS_NAIVE_TONSIL_BCELL_UP | MSigDB lists | GSE12845_IGD_NEG_BLOOD_VS_NAIVE_TONSIL_BCELL_UP | 183 | 64 | 17377 | 2626 |
NDUFA5,TXN,MRPS15,TAP1,MOGS,OLA1,PABPC4,SSR1,FLAD1,RAB8A,THAP4,SRI,AKR1B1,BAK1,TDP1,SEC61B,SELPLG,GNG7,PPIE,PSMB7,HTATIP2,ICMT,SLC25A5,PEF1,STOML2,HSPB11,TMED10,PSMD8,OGT,KPNA2,ATF6,SNRPG,AP2S1,SMAP1,MAGEH1,PPP1R2,SCAMP3,GOLPH3L,DAP,UFC1,FLOT1,NDUFA4,FAM136A,MLX,INTS7,NDUFS8,PPA1,PREB,SMC4,SLC25A1,RANGAP1,EXOSC9,ICAM2,RHOB,SNRPA,FAS,MAGED2,PLD3,ORMDL2,PRDX3,CTSA,HMGB2,SPCS3,YWHAH |
| 1.918e-11 | -24.68 | nucleoside-triphosphatase activity | molecular function | GO:0017111 | 840 | 201 | 17224 | 2647 |
RAB14,DDX47,ABCC10,YTHDC2,TAP1,DHX8,ABCB10,KIF2C,ATP5PF,KIFC1,RAB8A,RAP1A,CDC42,EIF4A3,RAB35,XRCC2,RAB4A,ATP13A3,DNM2,KIF22,EIF5,ABCC5,SNRNP200,RHOBTB3,NRAS,SEPT9,KIF15,DDX20,ARHGDIB,PBRM1,MCM2,RFC2,RAB5B,LSG1,RAB22A,DHX15,RAB2B,GINS4,ARF4,RHEB,SEPT1,RAD18,KIF18B,CHD3,MYO18A,ATP6V0C,CLU,VPS4A,PSMC1,LONP2,ATP6V0E1,DDX42,DDX58,HSPH1,RECQL,MUT,RHOC,CHTF18,GSPT2,DHX9,RAB23,KLC1,KIF23,TOP2B,RAB6A,MYL6B,TMEM250,DDX56,SMC3,MCM5,KIF13B,EFTUD2,MSH2,ATP6V0A2,GNAI2,ATP6V0D1,ABCC1,DDX28,NTPCR,NOA1,DHX29,GTPBP4,SEPT8,KRAS,RIT1,SEPT7,EIF4H,ABCF1,CCT8,RHOB,PSMC4,XRCC5,GNAS,NSF,ATP5F1A,RUVBL2,RBBP4,MYO9A,RHOG,ABCA3,RAB11B,DYNLL1,CHD1L,RAC1,PMS2,OLA1,MYH9,SMARCA4,RRAGC,EFL1,ATP6V1B2,GNB2,CHD1,RAB21,ATP6V0B,ATP2A2,RALB,KIF14,PIN1,SEPT11,TAP2,AQR,DNAL4,DCTN1,ATP6V1G1,RFC3,ATP13A1,RAB7A,ATP6V0A1,RAB1A,DHX57,RAD54B,DDX17,KIF2A,RAD51C,IDE,ATP1A1,HSPA4,RAB24,DHX16,XRCC3,ABCA1,DYNC1LI2,TUBB,RAD51D,RHEBL1,POLQ,KIF3B,SHPRH,TWNK,TOR3A,DCTN2,MYO9B,ARF1,ATP5F1B,BLM,IFT27,RAB11A,GFM2,WRNIP1,KIF5B,GTPBP3,STARD9,ARF5,ABCD1,DDX31,GTF2H2,MSH6,MYO5A,GINS1,RHOA,DDX24,HELB,BTAF1,ABCF2,ATP2C1,TUFM,BMS1,ATP5MF,RHOT1,DDX39A,GUF1,KIF11,MACF1,RHOT2,HSPA1B,MYO1F,DDX23,MFN2,RAB18,GNA12,UPF1,ATP6V1D,KIF18A,ATAD2,ATP5MC3,DDX5,ASNA1,ATP6V1C1,HRAS,DDX52 |
| 1.941e-11 | -24.67 | GNF2_H2AFX | MSigDB lists | GNF2_H2AFX | 30 | 21 | 17377 | 2626 |
FOXM1,ASPM,PTTG1,CENPF,RRM1,CDCA8,RRM2,DNAJC9,NUSAP1,MCM2,CCNF,SHCBP1,CCNA2,PCNA,KIF18B,BIRC5,H2AFX,PRC1,HMGB2,CCNB2,SMC4 |
| 2.007e-11 | -24.63 | pancreas-carcinoma-ductal_carcinoma | COSMIC cancer mutations | pancreas-carcinoma-ductal_carcinoma | 16044 | 2466 | 17385 | 2587 |
HECA,ZBTB10,ABCC10,HEXB,TGOLN2,CCNL2,FBXO22,EEF2K,THAP4,RAD23B,ATP13A3,ZNRD1,FTSJ3,USP34,CCDC57,ERCC1,NRAS,EHMT1,KIF15,HNRNPF,WDHD1,MIER2,DIDO1,MCM2,RAB22A,SMAD2,MID1IP1,RPS27A,MYO18A,OGT,MPV17,COX5A,SMAD1,ZNF75A,ANXA11,SLC25A33,SEC61G,GGA1,MUM1,TRIO,CUTA,RAB23,KCTD17,HAUS4,EIF2AK4,APH1B,CDC73,MYL6B,ATG4A,TMEM179B,PDXP,SMC3,GEMIN4,MVP,NUP85,PABPC1,NSUN4,PPA1,IFRD1,AGGF1,FOXK1,RBM42,GTPBP4,MAP7D1,MRPL16,ELK1,EIF4H,RDH11,MAGED2,KPNA1,ETS2,TYW5,WIPI2,RUFY3,PDLIM5,ACSF2,EXOC3,RHOG,STARD7,VTI1A,C5orf30,SLC35B2,INO80E,RCOR3,LCLAT1,CPNE3,KIAA1147,RBM23,ZNF420,AHCTF1,TBC1D22A,TBC1D14,GMEB1,NSFL1C,SEPT11,GPD1L,ZC3H3,ARL5A,PDCL3,SNX8,ERMP1,EID1,IDH3A,POLR2D,HTATIP2,MEF2D,TMEM147,GSTCD,TANC1,MAT2A,VPS26B,CORO1C,NSMCE2,CAMKMT,PPP5C,PITRM1,TUBB,COMMD10,ZNF445,SRSF6,HABP4,CCM2,FLOT1,BTN3A1,ATG2B,ABHD14B,PPP1R3B,ZBTB45,HUWE1,ZNF260,NAA50,ANXA5,LTN1,UBE3B,NAP1L4,ZNF710,ST8SIA2,SPTAN1,STAU1,DDX24,TCTEX1D2,TACC1,MRS2,LDHA,HEBP2,LLPH,RAB3IP,TTC33,PICALM,SH3BP5,SLC19A1,ACOX1,FAM3C,AEN,PARP10,YWHAH,THAP5,GPATCH4,FAM129A,TRIM11,YTHDC2,SNX15,RBM8A,ENSA,NENF,SND1,RUFY1,TRIM65,ZER1,PRNP,KRR1,RAB8A,NUP210,NT5DC1,NOC2L,EIF5,TACC3,VPS13B,PTPN18,MIOS,SNRPB,MBLAC2,CDC6,UTP3,PBRM1,ODC1,USP21,TRAM2,FBXO28,BCL7C,ARRDC1,ADAM9,DVL1,NUMB,ZNF564,FUBP1,C1orf74,CTU2,PARP12,ZCCHC9,CENPF,LAMTOR3,CHCHD2,NCKAP1,LYRM2,RSAD1,TNS3,SUB1,RINL,SSBP3,KIF13B,MBD2,XPA,AHCY,RBM3,MRPL48,LRSAM1,HDHD2,NTPCR,NSDHL,AMD1,CAMSAP1,ZNF761,METTL22,ICAM2,STYXL1,APPL1,BBS12,RXRB,SDHB,PCM1,GALNT2,TMEM168,NLRC5,RUVBL2,BTBD10,MYO9A,CCNB2,USP7,GLT8D1,RPLP2,SUCLG1,ARID2,TMX4,SLC2A1,ATP6V1B2,PCBP1,LYN,BCAP31,VAV1,MRPL50,TMEM69,PSMA6,ZNF473,ZNF302,BRPF3,TARDBP,BCAP29,CTDSP2,PRPF19,PPIF,KDM3B,MND1,CLCN3,BIRC3,RAB7A,ANKRD33B,PPIE,CHMP2B,VDAC1,EIF3H,TMEM201,GLOD4,IDE,DHX16,UHRF2,CHMP4B,XRCC3,PARD3,BCL2L12,C19orf53,MCM10,KLHL21,PDAP1,TMX3,CDCA8,ARF1,SLC12A9,TUBGCP2,DNAJB9,HOMER1,WBP1L,POLR1B,RNF5,RBM15B,PPAN,RHOA,RPRD1A,BTAF1,TOP3A,ARHGEF12,PCGF1,DDX23,RAB18,CACNB1,TRIM26,PDCD6,ATP6V1D,L3MBTL3,FAM110A,NEIL3,CTBS,BBX,IMPDH1,TAF12,NR2F2,PGAM1,HIPK3,IFI16,TXN,NUP188,H2AFZ,PRKCSH,USP39,UBE2I,PARK7,SLC25A37,ASPHD2,ZNF428,RAB4A,TRA2B,SUCLG2,TAF5L,SMARCE1,ZNF800,CDC5L,ZNF524,SGCE,OSBP2,NSUN2,USP22,CLNS1A,EIF3A,ZMYM3,DOT1L,IWS1,ANKRD10,WAS,KIF18B,TPP2,C1orf109,ZMAT3,B4GALT2,PRPF38B,RECQL,C9orf78,EWSR1,GADD45G,RRM1,ACAP1,B4GALT1,CYCS,FAM136A,SUPT7L,TMEM165,CNOT3,WDR48,SPAG5,RTKN,CEP104,EXOSC7,KLHL5,LRRC8D,PPP4R1,MSH2,PIGG,OSTF1,FBXL7,MRPL40,TNRC18,SYTL3,FAM171A1,APOL1,EIF5A,GCC2,PRIM2,ELL2,RDH10,MFNG,RPS24,GORASP2,CAPZA2,ADRB2,CCT8,MTR,PHF6,PFDN5,SLCO4A1,TTC13,GOLGA2,RBMX,PIAS2,APPL2,SAMD8,NUDT3,CDKN2A,ZNF511,ATXN3,RAF1,KIAA0232,C2orf49,CD320,EPM2A,CCNA2,MTMR4,BRI3,TP53BP2,AQR,RBM12B,ILKAP,CDK12,SAP30,BRD4,DRAP1,NARF,LRRC8A,ELP4,ABHD11,PKMYT1,ASB13,SERP1,TRIM28,SUPT16H,EIF3K,CHMP4A,ATF6,XRCC4,ADAM23,PRPF4B,NDUFS1,DEPDC1,MECP2,SECISBP2,HMG20A,WWP2,JAKMIP1,SLC25A36,CCNK,DNAJC8,AXIN2,CITED2,JMJD4,ANKRD37,KAT2A,TMEM126B,RABIF,ADSL,PACS1,BMS1,KCNQ1,ARSK,MACF1,KIF11,KLF6,COMMD4,SMAP2,FADD,SH3GLB1,MYO1F,CBX3,TMEM127,INF2,PPP1R11,DUSP11,DDX5,WDR62,TAF6,ESPL1,PURA,DDB1,DEF6,FAM83G,IPO4,UBL3,PIGM,NAT9,LYRM4,GPR132,UBE2Q1,PTP4A3,BRIX1,MRPL19,ZNF696,SF3B2,PCYOX1L,CDC42,GOT2,JAZF1,HADHB,RPF2,SLC35C2,CNNM3,CARM1,SRPK2,WDR41,LARS,ZCCHC10,CCDC138,LRBA,SUMF2,KMT2C,OGFR,PRPSAP1,ASF1B,RPL37,MAN2A2,EIF4ENIF1,NIP7,U2SURP,MIA2,ATP6V0E1,PPP1R2,PM20D2,XPNPEP3,RGS2,LYAR,FAM89B,POLR2I,TRAFD1,SUGP2,GBA,EIF2A,SYVN1,DAPK3,ARHGAP15,MASTL,UAP1,NFIL3,FN3KRP,YWHAZ,CTSA,TMEM14A,TOB1,TSEN15,ADNP2,TCF12,PRKAB1,MDH2,SMARCA4,ORC1,RRN3,UBXN2A,IARS,CD3EAP,KIF14,EXOSC1,CS,CLTB,DNAL4,CSTF1,POU2AF1,UBQLN4,NXT1,HPDL,PGGT1B,SELPLG,SMU1,ATXN1,GLO1,OGDH,BICD2,CADM1,EDEM2,HERPUD2,TOLLIP,FANCE,MBD3,PDHX,RPS9,ALKBH6,SURF4,DUS3L,ARNTL,ANP32E,FKBP5,TMEM101,CCDC125,ABCA1,PDCD2L,GCLM,RAE1,DCTN2,NUP54,CHIC2,PAWR,MXD4,DCUN1D4,PIP4K2A,XPR1,KIF5B,KLHL20,SEC24C,RRBP1,ARHGEF2,LDLRAD3,STAT3,MYO5A,NIPAL3,AMPD2,TXNL1,PHF20L1,DCAF6,FAM49B,TMEM39A,ATP2C1,RFFL,COG1,RCOR1,PRMT2,TFEB,LEMD2,UPF1,ELMO1,ZC3H7B,DTX4,ZMIZ1,TERF1,HRAS,CCDC93,FGFR1OP,TMED7,PIGQ,AGPAT1,CNTROB,PPP1R16B,MIS12,GSDMB,TTC9C,PDS5B,NUP153,SENP1,PGAP2,TMEM115,PLEKHM3,DCUN1D5,PLEKHF2,BRMS1,PWWP2B,TRIM47,WDR11,AXIN1,SMG9,TRIM52,LONP2,NDUFV2,PHF23,CERK,SLC4A2,EZH1,ITGB5,LMNA,MCTS1,DDX56,EIF2S2,SLC38A5,FOXN2,CARS2,PRRC2A,C16orf72,RB1CC1,ZMYND11,PGS1,MYBL2,UHRF1BP1,SRSF5,MPG,MATR3,CYB5A,NCDN,POLR2J,SETD3,PTAR1,CNOT6,NDE1,EGLN1,ZNF207,ANKRD27,ABCA3,SARNP,IVNS1ABP,MON1B,RMI2,TMEM97,NIT2,NUF2,ZNF267,TCF19,TMEM161B,KTN1,APP,PRKD3,CLUAP1,ATP2A2,UTP18,DUT,ZCCHC2,ANAPC7,RNF19A,FAM76B,CLN6,TMEM9,GCC1,RNF169,ADCY7,ATP6V1G1,ENPP4,RNPS1,CDCA2,FKBP3,GPR137,DDX17,CHCHD3,PEX5,CDC16,HIPK2,MBOAT1,TICAM1,PDXK,ZBTB11,ANXA6,TMBIM4,GMCL1,UBE4A,IL21R,ETS1,WRB,ZNF92,PNO1,CAPN2,ADD3,SUV39H2,TTLL12,TPCN1,TMX1,LYPLA2,HNRNPM,LDHB,PPP3CA,NUDT8,POLK,JTB,EMP3,MTMR12,ZP3,PDE3B,KIF18A,CCDC6,WNT5B,MAPK6,LY75,C4orf46,SLC25A19,RGL1,PSAP,WDR76,IGBP1,FAF1,SNAPIN,COX15,THOC1,AGRN,GNPDA1,GPBP1L1,PPP1R15B,CSNK2A1,EBNA1BP2,GIT2,BIRC2,ATPAF1,DLG5,ABL2,XRCC2,ZFYVE27,MCMBP,PTPRK,CDC37,METTL1,SP3,EXOSC6,HARS,GMFB,ESYT1,ANLN,RAB5B,RHEB,DPYSL3,TBC1D17,TIMM13,CDCA4,TONSL,NRM,NAGLU,ACTB,ZNF45,TMUB1,CTCF,ASAH1,DOCK11,CRLF3,LRRC14,NUS1,SLC27A4,AFF1,MDFIC,MAML1,CYTH1,NQO2,UTP15,EIF2AK1,EIF4G2,ZDHHC3,MOSPD3,ITPRIPL1,CDC27,SNAP23,TBPL1,PRMT7,KCTD7,NDUFA5,CYLD,UGP2,DYNLL1,COPE,HCFC1R1,ZADH2,GGPS1,RAD23A,ATP6V0B,PDK2,STRBP,DUS4L,MRPL34,PDCD2,SAP30L,SLC39A9,CLPTM1,RPL29,RPL35,BTG2,DNAJC9,MTMR6,FRAT2,NFATC2,KDM1B,ARL5B,USP36,CCDC127,MRPL2,ATP1A1,CLK3,PSMD3,MAFK,CEP55,NDUFA11,DNAJC17,ZNF436,NCOA1,SLC25A39,ZC3HC1,ZNF146,ATXN7L2,CDC40,GOLIM4,SMAP1,RRP15,DAP,GNE,SMC6,ARFIP2,NKRF,CHAC2,BZW2,WRNIP1,SS18L1,CENPM,PTGES3,CAMK2G,MLEC,ZNF202,PPWD1,FAM50B,RHOT2,NEU1,TPD52L2,GOLGA7,TWSG1,GLG1,PGRMC1,FAM126A,RPS6KC1,UBE2C,PPCS,NDUFB6,TMEM41B,ZDHHC8,PLXNA1,CCNB1,SLC20A1,COMMD6,ABHD14A,POLR3K,C14orf119,ASAP2,SNUPN,PLCL2,TFG,SEH1L,ATG9A,PBK,MKI67,DDX20,AMDHD2,SLC17A5,GALNT7,CCNF,FOXRED1,PTER,WDR4,DHTKD1,TRAF5,HDAC2,PWWP2A,HSPH1,MAPRE1,CHTF18,ADO,KIF23,SLC35B1,NOTCH2,JMY,FKBP1A,SLC31A1,SNX18,ATIC,ATP6V0A2,PIKFYVE,RNF135,LPCAT1,EEF1D,TMED2,FTL,PHF10,DDX28,ZNF84,SIGMAR1,PIP4K2C,RIT1,PLEC,KDM3A,SF3A2,FAS,EPRS,ZNF777,TMEM54,QARS,PPP3R1,TCOF1,NRBP1,CABLES1,DNMT3A,RWDD1,CKLF,TRIP10,SF3B1,RPS6KA1,SUZ12,CAST,RAC1,GPR89A,OLA1,SNN,GNB2,FLAD1,APLP2,KDM2A,TNPO2,CDKN1B,TALDO1,GPX4,ATP13A1,MAPRE2,RFC3,ERF,CUL3,SLBP,H2AFV,POLG2,GAR1,PSMB9,DHX57,NSA2,HSPA4,MRPL55,JAK1,TBL3,GOLGA8A,SEL1L,H2AFX,KLHDC4,B4GALT3,PDCD11,ATMIN,POLQ,POU3F2,OTUD5,NCOR2,ANKRD13D,PKP4,SCAMP3,CDCA3,SLC25A12,BLM,TMCC3,GTF2F1,RPL17,CRAT,AHSA1,PRC1,UPF2,COPS7B,SLC38A10,CNOT6L,CNPY3,UBE2M,IFT46,TMEM160,TSHZ1,ZFP64,DENND4C,WDR18,RPL8,ILF3,LRRC1,RHOT1,TSR2,MARK2,ECH1,PRDX1,PLD3,NUCB1,GNA12,FBXO21,C1orf131,PRDX3,PFDN4,HNRNPH3,STX18,TFDP1,KHSRP,ASNA1,CPEB2,SSSCA1,VPS29,BYSL,S100PBP,MIB2,IER2,PTMS,NOP2,UBN1,DCAF15,NF1,ALKBH5,MOGS,TAF6L,BECN1,MAPK14,SNAPC4,RNF103,BCAT2,MBD4,C18orf32,METTL14,IMPAD1,ZNHIT6,RCSD1,PHTF1,SRI,KIF22,ZBTB22,NFU1,OGG1,TRIM14,ELOF1,COPS8,FYTTD1,TRIM8,RRM2,SOX4,ABHD5,CXXC4,UBTF,PAF1,UEVLD,SPATA2,PQBP1,IARS2,ATXN2L,GALNT10,STARD3NL,RPS15,PIGN,AGTRAP,CIB1,XPO7,SRRT,ZNF449,CAPZA1,GLTP,KIFAP3,BCL2,N4BP2,HP1BP3,THNSL1,ISG15,CAND1,C22orf46,GNAS,TSC1,RBM25,CDCA5,ZFP90,NANP,RBBP4,ZBTB24,SMARCD1,MBD1,WASF2,MMACHC,TOMM20,IFI27L1,GNPNAT1,MPHOSPH8,HNRNPUL2,CHD1,MEAF6,C2orf68,CCDC50,AKAP8,PARL,RPN2,CHTOP,FAM3A,F2R,SCYL3,TMEM14C,ABI1,HTRA2,MOSPD1,RLIM,FAM172A,ZNF500,PSMB7,NLN,WIPF1,BOLA1,BUD13,NDUFB1,PEF1,EIF3G,BTBD1,TAB2,CHCHD1,TULP3,WDR59,CANT1,SCARB1,GAS2,USP11,SMURF1,TSPAN5,PPP2R2D,CDS2,MAGEH1,MRPL42,EYA1,CDK2AP2,MRPS26,LETMD1,KLF13,HDDC2,RGS1,MAN1A1,FBXO5,GART,TANK,BRD7,MRPL11,SAMD4B,ZDHHC18,GTF3C6,POLR3GL,WDR81,MEN1,ZNF407,MFN2,COX8A,ZRANB2,SRSF3,MBD6,ATP6V1C1,IDH3B,TATDN1,TSC2,LACTB2,CMTM6,RBM4,ZNF275,RPL23A,CDKN2C,NAPG,USF1,DNAAF2,MECR,AP1M1,UPRT,CRY2,ECD,RNF26,TIPARP,LRRC59,ANKRD9,RHBDD2,MGAT5,BAK1,ZNF559,RHOBTB3,GABPA,WBP1,NUTF2,ARF4,GINS4,KRIT1,BOLA3,AHNAK,RAD18,PDRG1,RNASEL,CHPF2,OAZ1,SMNDC1,PDCD4,NXT2,HIVEP3,KIAA0100,CLSPN,RHOC,DHX9,PDCD7,PSMD9,HAUS2,COPB2,CD59,TFAP4,RNFT1,RIMS3,EFTUD2,FBXO7,CPSF4,MRPL21,PHKG2,LUC7L2,SRSF11,EIF3L,MTA2,TYW1,USP10,ITM2A,SSR2,BCLAF1,MTX1,SFXN5,FNTA,PDLIM1,TXNDC16,TMEM159,MRPL3,ALS2,FAM72A,TRIM41,KARS,NQO1,POC1A,ANK3,PTTG1,TPX2,TBC1D13,DAZAP2,STMN1,C19orf48,REPS1,ABHD16A,FBXL6,SH3BP1,MTA1,UBA5,CLCN6,INTS12,C8orf59,RPRD1B,CGGBP1,CPNE1,SEC61B,POLR2L,FAM118B,GOPC,E2F3,CIRBP,RPL38,CRNKL1,PFKFB3,GORAB,RAB1A,GIGYF1,TMEM184C,PPP2CA,KIF2A,CCDC14,LSM6,RNF38,SNRPG,DMWD,USP13,ZFP91,TRMT6,IP6K2,WDR5,SLC25A43,PMVK,IFT27,NEIL2,RRP36,SRXN1,RPA2,PSMD2,CLIC4,PDCD10,CBWD2,COQ4,ITGB8,ARF5,ARHGEF1,FBXL19,GTF2H2,TTPAL,UTP20,MAGT1,GPS2,DBI,SSNA1,MRFAP1L1,CD81,TMEM131,WDR13,FANCI,PAPOLA,CREM,FANCL,GLIS2,IL6ST,INTS1,POP7,SLC44A1,MTPN,ASB6,PLK1,RPP25,SEPT9,CELSR2,RBX1,APH1A,RAD51AP1,CKAP2L,PSMG1,UBE2V1,EAF2,IL12RB1,KRTCAP2,LUC7L,LSG1,NECAP2,C1orf122,TRIM4,AGPAT2,CHD3,ZNF367,E2F4,PRPF4,KPNA2,BEND6,CLN3,DNAJC30,NGLY1,POT1,MYL12B,CCDC137,RMND5A,HJURP,PHB2,DNAJB2,FAM53C,NKD2,SDC2,KLC1,CDK13,ADCK5,COX4I1,DNAJB1,RAB6A,ARID1B,C1GALT1,MLX,UBE2Q2,CCP110,ZNF746,ARL6IP1,CTR9,NIPSNAP1,ABHD2,DCAF8,ACSL3,LDB1,MAP4K3,ARMC8,NMT2,IRF5,RPL36,HAUS8,MBIP,ORMDL2,COX7A2L,ZDHHC7,SIL1,FAM122A,UNC13C,BCCIP,SART1,TRAF7,NDUFAF2,TOR1AIP1,ZNF416,LAGE3,ZFYVE21,TM9SF3,RRAGC,ZNF121,OIP5,NRF1,WDR44,PIN1,EFCAB11,RPAP1,CABLES2,LMAN1,AHCYL1,TOP1MT,STRAP,SPSB3,ZNF583,SNX25,ARHGAP17,POLR2G,ZNF780B,PPT1,NUP155,DCLRE1C,MRPS14,RHBDF2,SUGP1,RBL1,FASTK,STK38,AP1S1,SPRYD4,H3F3A,CHID1,SMAD4,RAD51D,SLC30A9,CMAS,UNK,NADSYN1,HMGN3,NCAPG,SCYL2,FZD6,HERC3,GTPBP3,CTSS,ORC3,RNLS,YTHDC1,ACP2,HMGN5,CSRP1,METTL5,ABCF2,TUFM,RANGAP1,PNPLA8,HAGH,API5,ZFR,SEC23IP,E2F1,TMEM219,USP20,RBPJ,PDCD6IP,MAX,LUZP1,GXYLT1,ADAM10,CXXC1,TSC22D3,AP3M2,CUL1,GYG1,NANS,OAT,MYEF2,ANKRD26,PA2G4,NOL11,FIZ1,ZNF200,MARCH2,SLC26A2,SRP72,KLF10,LACTB,RFC2,CBFB,RAB2B,PRIM1,MAP3K4,HHEX,LUC7L3,RPS14,MAP4,MRPL27,BTF3,PTPDC1,NMD3,CCDC59,PTOV1,COX5B,DNAJC5,SCOC,DHPS,POLR2K,ANKH,C16orf87,PRKAA1,VAV2,GSPT2,DLGAP4,PXMP2,PRPF39,PSEN1,ZNF79,PDXDC1,VPS25,NDUFS7,YY1AP1,C12orf10,FAM192A,RPN1,LHX8,ARPC5,ZNRF2,TPST1,DAPK1,PIK3IP1,CYC1,SOCS5,FDFT1,PIGT,EMB,WDR1,ZNF574,C1orf35,EXOSC9,ARID1A,PTTG1IP,C9orf40,FXR1,GOSR1,MAP2K2,TWISTNB,AKAP1,XRCC5,HMGN2,PI4K2A,CAT,SEC31A,DERL1,HSPBP1,MTHFD2,CEBPG,ARAP1,USP32,FAM83D,CABIN1,SMPD4,GPI,CYTIP,TP53RK,REPS2,RAB11B,UROD,SLC39A13,POMP,BCL2L1,NUDT19,DECR1,RALB,SIAH1,ADCY9,LPIN2,MRPS27,SOCS6,TTC3,RNASEH2A,CFL1,ANKLE2,CDC123,OAF,VDAC2,EDF1,EML4,ERC1,ANKZF1,RAD51C,ZNF282,DSN1,DDOST,HINT1,DGCR8,SAFB,HAGHL,FTSJ1,LMBR1,RWDD4,NCLN,BEND3,EYA2,DYNC1LI2,SLC41A1,MANBA,B4GALT5,TKT,FAM76A,CBLL1,ARGLU1,LANCL1,POFUT1,FAM8A1,HEATR5B,HLA-A,EBP,RFWD3,NDUFA2,FUT8,BTF3L4,PTPN11,MRPL54,FEM1B,RPL19,CNN2,NDUFA3,MTX2,MSH6,PDLIM2,LONRF3,RFXANK,FBXO9,GUF1,RPL32,ZHX1,NDUFS5,WDR91,GPR89B,HIGD2A,ZBED3,RORB,POLA2,ZNF76,COPA,HMGXB3,PHRF1,ABCB10,COMMD5,MAP1LC3B,DST,SIVA1,RAB35,GPATCH1,TCEA1,DRAM2,DEAF1,SNRNP200,NCK1,LAP3,VHL,SREK1,ARHGDIB,PITPNB,HSPB11,BRWD1,PPM1G,SH3GLB2,CRCP,BAZ1B,ACBD4,CAB39,STK11,CLU,CHEK2,ZSWIM3,TSTD2,CHPT1,MRPL13,DCAF5,CAPN1,UBE2D3,NSMCE4A,PPP1R12A,ZCCHC8,GORASP1,UBXN1,NACA,PCSK7,RPL15,THRAP3,TTF1,QSOX2,PRPF18,NUP205,CHKA,MED10,ZRANB1,MCPH1,SLC12A2,ATP6V0D1,CSNK1G3,CREG1,NUDT4,RPL6,VKORC1,SLTM,EVC2,KLHL15,SIAH2,SLC16A1,EHD4,SNRNP70,C11orf1,APOL2,N4BP2L2,SNX27,CHMP2A,CORO7,PMS2,UCK2,UCK1,CLCC1,EXT2,MXD1,USP5,HNRNPA2B1,SAP130,NVL,PPP6C,CYB5R1,ZNF770,EBAG9,RNF25,PCGF6,METTL2A,FAM72B,PON2,HNRNPR,STAT6,HPS5,MAPK1,BRD9,TMEM33,NAT14,DNAJC2,TRIP12,SHPRH,SCYL1,VPS45,MYO9B,GFM2,SPPL2A,FASTKD3,FGFR3,MZT2A,PPIG,ZDHHC13,TMEM99,H2AFY,ATG13,NDUFS8,ERI3,FBL,SLC35A1,FRMD8,MICAL3,TGFB1,B3GALT6,ELOVL5,HEMK1,TIMMDC1,HELB,PSPC1,MIER1,SCFD2,NDRG3,CDK11A,MTMR3,ACAT1,CENPT,PLOD3,RAB3IL1,ZSWIM6,RAB14,ADD1,MRPS15,KDM4A,XIAP,DHX8,GLUD1,ANKRD23,PABPC4,CALM2,CDK5,PSMD1,NEK6,NSRP1,RABGAP1L,SRSF4,FNIP2,KCNAB2,PCBP2,MLST8,PLK3,ZNF672,MRPL43,HSDL1,TOPORS,MCL1,SMC2,PPFIA3,ICMT,SLC50A1,STOML2,LIMK1,ZNF689,PRDX5,ATE1,MLYCD,ATP6V0C,ST3GAL2,FBXL3,TFDP2,E2F2,PFKP,AAAS,DDX42,SSRP1,MRPL9,MRPS2,STRN4,TOP2B,ZNRF3,TMED3,DDRGK1,RAVER2,GNS,INTS7,INPP5A,MCM5,PHF14,ZNF326,UBE2QL1,NAGPA,TIMM8B,ETV3,TSPYL4,DHX29,TEX10,MAN1B1,RPS10,CBFA2T2,ABCF1,RHOB,LRRC14B,DTWD1,PTPRF,SCARB2,OSBPL11,CCDC86,DUSP3,SLAIN1,MDH1,HEXA,RNF139,SNX14,ZNF296,TRERF1,UBR2,CHD1L,ACTR3,WDTC1,MYH9,CREBL2,NIPA2,PRKACA,SAFB2,ANKIB1,STAM,ARL6IP6,RAB21,SP100,ZKSCAN1,DDA1,NUP107,ANKRD13C,MAVS,CEP63,TMEM136,RBM15,ATF2,DCTN1,SHOC2,PSRC1,MAP4K4,WBP2,ATP6V0A1,NDUFA7,DNAJA1,TAZ,C19orf54,TAF2,SEC61A1,WDR7,RPLP1,CBLN2,RBMS1,FUS,GEN1,LRP8,COIL,LRCH1,GALK1,ZNF786,RPS2,SESTD1,TRAK1,JMJD6,SIKE1,AKT1S1,KRI1,FBXO3,ERH,PPP1R8,PRDM4,GTSE1,GEMIN6,DCP1A,SGCB,S100A6,IMPA2,NUDC,PDPK1,TK1,GUK1,TNFAIP3,GALC,ZNF512,KIAA0930,MRPS10,DDX39A,RPA1,ZNF180,ZNF862,KEAP1,POLE,TATDN2,PITX1,CAPN7,LRPPRC,PML,HMGB2,USF2,ANAPC4,SRM,DDX47,MCCC1,CDC42SE2,S1PR2,CDIPT,SEC16A,SSR1,LIN9,PCNA,ZNF639,PIK3R2,ETV6,TXLNA,PPCDC,FAM86C1,MYBL1,MRPL32,CCAR1,ABCC5,PBXIP1,TLK1,MRPL12,EZR,LNX2,LRP5,BRCA1,PRKRA,STX16,EPB41,OPTN,SEPT1,SOCS4,QRSL1,PIEZO1,GLCCI1,NUDT11,GEMIN7,SEPHS2,LZTR1,RACGAP1,PPP3CB,B4GALT4,RLF,RAPGEF6,SNRNP25,RB1,VASP,MED8,VMP1,PPIL2,MEA1,TIMELESS,AHDC1,ALDH18A1,TMEM8A,ABCC1,PREB,TRAPPC9,AACS,MEMO1,KRAS,RTF1,UBE4B,NFATC2IP,LY6E,ARPC1A,ZNF174,PSMC4,GOLGA4,PALB2,SYNCRIP,PRPS2,NIPA1,TIGD2,RNF114,FOXM1,MRPL39,XAB2,SUMO2,DUSP22,COMMD8,RPL11,CSDE1,MDM2,CORO1A,MINPP1,METTL9,POC5,DVL2,GM2A,PSMA8,COQ10B,CPOX,TIGD5,SLC26A6,CYP20A1,PRPF3,TXNL4A,RPSA,SRSF1,DNAJC10,SCAP,ZNF700,PLEKHG4B,TIMM17A,FAU,LTA4H,AP2S1,USP53,INTS2,CTDP1,MIF4GD,CDT1,ARID5A,SUMF1,GGA2,AP3S1,CSNK1A1,RMI1,TFRC,PTPN2,STARD9,IRF4,GSTK1,NDUFV1,SLC1A4,CWC27,SLC35B4,DDX31,ABCD1,RPAP3,CNTN5,SNX2,ZMYM5,CCDC34,CHCHD6,BSDC1,KPNA4,CDKN2AIPNL,FBXO41,BIRC5,TFE3,SNAP29,CDCA7L,PKD2,ACADM,CHMP7,SAT2,GCSH,ZNF496,TMEM109,TAP1,YTHDF3,NHLRC3,IKBIP,EIF1B,ELMOD2,KIFC1,DBNDD1,RNASEK,CDC25B,PRADC1,DNMT1,NOL12,ORAI2,USO1,AKT2,GNG7,AURKB,MCFD2,SLC25A5,ZFAND5,MAK16,STT3A,TMED10,PSMD8,EIF2D,ITGB1,PTPN7,UQCRH,RRS1,ARRB2,RTN3,ZNF598,SVIP,DDX58,WSB2,PPIB,MUT,GMFG,HLA-E,NDUFA4,MAN2B1,METTL3,CFLAR,NDUFS4,RNF121,MEX3C,KLF16,HDAC7,DAD1,BDH1,PCYT2,GNAI2,ANKHD1,TERF2,MORC3,KCTD20,SEPT8,DCTD,TOMM40,PATL1,ADSS,SERTAD2,SERF2,ZFP92,NSF,DCK,ERGIC3,ACLY,LPCAT4,VCPIP1,YY1,PPP6R2,MAP3K5,PPP6R3,RNF14,CDK2,ZC3HAV1,ZBTB37,URB2,EIF3D,MAGED1,KLHL18,ADPGK,SLC25A44,AP1B1,SDHA,PAIP2,PHC2,CRKL,MOAP1,TERF2IP,CYHR1,ZNF75D,SHC1,UCHL5,NAA35,TMBIM1,CCT2,CDKN2AIP,MKLN1,HMGN4,GALK2,CDC23,SHCBP1,AP4E1,PRDM11,VEZF1,PPP2R5A,ACYP1,STAT1,PPA2,TRIM32,RHEBL1,C1orf112,TCF3,MRI1,BRAP,AGPAT3,MYNN,SDF2L1,SPR,RAB11A,REEP5,FOXO3,MAD2L2,CCDC28A,PIP5K1C,RBM17,MAT2B,PTEN,CENPJ,TAGLN2,OSTC,CREB1,PACS2,NCOA2,SMC4,RNASEH2C,NEK7,NET1,PARP4,TBRG4,ANAPC2,RPL27A,YIF1A,SGSH,HGS,TTLL4,SLC38A7,MFAP1,CCDC69,BRWD3,ESYT2,SKA3,NPHP4,UBE2E2,HNRNPAB,PLXNC1,TMEM184B,ST13,DNAJC24,ZNF107,SLC29A1,KIF2C,AGFG1,SIRT2,FKBP2,USP48,SNRPD3,UBQLN2,CUTC,EDC3,UBLCP1,ZNF804A,RAP1A,THADA,EIF4A3,AP3S2,ATG3,DPYSL2,PPP1R12C,AKR1B1,NDUFB9,JOSD1,RP2,TTC4,TECR,ARID4A,FGFR1OP2,TIMM50,TDP1,DPM1,FOPNL,SLC16A7,WDR82,SLC25A22,STK17B,DHX15,CHAF1A,GEMIN5,COPS6,SASS6,RPS26,PSMC1,SLC12A7,TBC1D12,TM9SF4,ZNF768,UFC1,MED13L,TIA1,EPHX2,PITHD1,RHBDD1,NFATC3,BANF1,ZNF335,BUD31,YBX1,KNTC1,ACAD8,UBE3C,ZNF189,ALDH9A1,KDELR1,TSTA3,CIC,OXR1,PSMA1,NAP1L1,ODF2,EXOC4,KIAA1328,NUP62,PITPNA,NAA20,PTDSS1,MZT2B,PDSS2,C7orf26,TMEM106C,IMMT,ASH1L,CHERP,WDYHV1,PLAGL2,CHKB,IRF3,TWF2,PAIP1,ANKRD28,ANKLE1,FARSA,SAR1A,SCAMP4,APOOL,PDIA6,ACSL5,TOR1AIP2,AZI2,GFER,RAD54B,DAP3,TMEM41A,ZNF317,GADD45B,AKNA,REEP4,CBX4,MIF,KIF3B,GOLPH3L,SH2D3A,CASP6,TOR3A,SRGN,DBF4,MFSD10,SAC3D1,CTNNBL1,YIF1B,CLDND1,TTC17,SLC25A1,PAQR6,CSNK1G2,TELO2,ADAM17,HMGN1,NASP,ASPM,PRKAR1B,SYMPK,TARS,SNRPA,MAPK3,HSPA1B,HLA-B,ATAD2,PLAA,ZNF330,OSBPL8,KBTBD7,PREPL |
| 2.028e-11 | -24.62 | V$GABP_B | MSigDB lists | V$GABP_B | 248 | 79 | 17377 | 2626 |
PRKAB1,CHERP,RAB11B,NF1,MON1B,EBNA1BP2,POMP,SYNRG,PCBP1,GNB2,BCAT2,C14orf119,SEC11A,PPME1,AP1M1,NOC2L,NUP153,TAF5L,MTPN,PCBP2,CSTF1,VPS13B,NRAS,DPM1,COQ10B,RAB7A,RNPS1,NUP155,HERPUD2,BTBD1,EIF3H,SUPT16H,DDOST,UQCRH,ACTB,GALNT10,ARRB2,GEN1,TSTD2,XRCC4,NAA60,TMUB1,MAPRE1,TMBIM4,SCAMP3,PHF23,PHB2,UBXN1,EPN1,SMC6,ASXL2,ZNF79,FAM192A,BANF1,UPF2,SLC38A10,TMX1,MORC3,EIF5A,PHF20L1,RHOA,MLEC,ACP2,WDR1,PPP1R21,TOMM40,PCGF1,C9orf40,RHOT2,PHF6,MAGED2,DERL1,SEC31A,TMEM127,RPL32,CCDC6,PPP1R11,DDX5,MRPL3 |
| 2.028e-11 | -24.62 | DHX15 (DEAH-box helicase 15) | protein interactions | 1665 | 192 | 69 | 17029 | 2761 |
CYLD,XAB2,SF3B1,CUL1,EBNA1BP2,PABPC4,PCNA,EIF4A3,PIN1,TXLNA,NSFL1C,NOC2L,RPF2,CRY2,RBM15,SRSF10,SRPK2,PRPF19,CDC5L,SNRNP200,HNRNPF,CUL3,DNAJC9,TOPORS,BRCA1,MCM2,SRSF1,IWS1,SUPT16H,DDX17,SUGP1,HNRNPR,EIF2D,PRPF4,FUS,ARRB2,DDX42,SLC30A9,UNK,GGA1,LMNA,MCTS1,RBM17,RPA2,MCM5,ZNF746,FUT8,MSH2,AHCY,KIFAP3,FBL,PABPC1,RBM15B,SRSF11,STAU1,TMEM126B,SF3B6,SRSF5,SF3A2,CAND1,RPL36,RPA1,SEC31A,SYNCRIP,RBMX,DDX5,SRSF3,CDK2,CD81 |
| 2.084e-11 | -24.59 | ZHOU_CELL_CYCLE_GENES_IN_IR_RESPONSE_24HR | MSigDB lists | ZHOU_CELL_CYCLE_GENES_IN_IR_RESPONSE_24HR | 119 | 48 | 17377 | 2626 |
FGFR1OP,DEPDC1,POC1A,PTTG1,CENPF,CDCA8,KIF23,RACGAP1,NUF2,CHAC2,CCNB1,SPAG5,FBXO5,KIFC1,RPA2,PCNA,CCNA2,NUP107,PRC1,TIMELESS,KIF22,KNTC1,CLN6,TDP1,NASP,ASPM,MYBL2,DNAJC9,NUSAP1,SMC2,MCM2,ANLN,BORA,KIF11,H2AFV,HAUS8,BIRC5,NEIL3,ODF2,CEP55,H2AFX,E2F1,HMGB2,KPNA2,SMPD4,CDK2,CCNB2,UBE2C |
| 2.106e-11 | -24.58 | GSE21546_UNSTIM_VS_ANTI_CD3_STIM_DP_THYMOCYTES_DN | MSigDB lists | GSE21546_UNSTIM_VS_ANTI_CD3_STIM_DP_THYMOCYTES_DN | 175 | 62 | 17377 | 2626 |
C1orf112,URB2,TMEM109,TPX2,STARD7,JMJD6,SLC29A1,BLM,TCF19,RMI1,SPAG5,SNRNP25,NVL,MCM5,PPIG,EFTUD2,POP7,TIMELESS,KNTC1,CLN6,DNMT1,NUP85,HNRNPM,TIMM50,PPAN,ANKLE2,TMEM115,PSRC1,ASPM,TEX10,MKI67,GLO1,PRPF3,BRCA1,TOMM40,CCNF,ICMT,DDX39A,CHAF1A,SRSF1,DDX23,CDCA4,KIF18B,DUS3L,FAM110A,HPS5,CDCA5,NRM,H2AFX,E2F1,AEN,SSNA1,PRPF4,SCARB1,WDR76,CHEK2,CCNB2,CABLES1,SLC25A39,CCDC59,ZC3HC1,ZNF511 |
| 2.193e-11 | -24.54 | GSE3400_UNTREATED_VS_IFNB_TREATED_MEF_UP | MSigDB lists | GSE3400_UNTREATED_VS_IFNB_TREATED_MEF_UP | 171 | 61 | 17377 | 2626 |
NDUFV2,HECA,CDC40,ZCCHC9,MUT,SHPRH,RACGAP1,GMCL1,ATG2B,CUTC,KIAA1147,PAIP2,RAP1A,METTL14,ATP13A3,RAB4A,TPST1,MSH2,BRD7,AKR1B1,BRI3,FBXW2,CITED2,LPCAT1,TMEM14C,CDKN2AIP,PHF10,HMGN1,ZNF559,DENND4C,DHX29,ZMYND11,ATP2C1,JTB,ZBED5,PCGF6,MTMR6,FBXO9,KRAS,NUP155,PLEKHM3,GALNT7,PPWD1,CDC23,SLTM,RDH11,C1orf122,DDX17,GNAS,HIPK2,ACOX1,DCAF11,ITGB1,ADAM9,HMGB2,NCOA1,RNASEL,ZNF45,FAM208A,CD81,MAPK1 |
| 2.225e-11 | -24.53 | RPL5 (ribosomal protein L5) | protein interactions | 6125 | 229 | 78 | 17029 | 2761 |
CYLD,NOP2,RPLP2,DHX8,CUL1,CSNK2A1,EBNA1BP2,KIF2C,BRIX1,RBM4,PABPC4,RPL11,RPL23A,MDM2,NVL,TARDBP,FTSJ3,RPL29,RPL35,HARS,VHL,RPL38,CUL3,BRCA1,MCM2,SLC25A5,MAK16,RPS9,RPSA,NSA2,SEC61A1,RPS27A,RPS14,RPLP1,RRS1,FAU,RPS26,PDCD4,PRPF4B,NIFK,RPS15,RPS2,MECP2,DHX9,RPL15,HAUS2,LMNA,DDX56,HUWE1,RPL17,RBM34,ZNF746,UPF2,RPL19,MAP3K14,FBL,PABPC1,ATP6V0D1,HNRNPM,HP1BP3,EIF5A,STAU1,DDX24,ZNF512,RPL8,ILF3,RPL6,RPS10,RPS24,RPL27A,CAND1,RPL36,NAP1L1,CDC27,RPL32,PML,CD81,IPO4 |
| 2.298e-11 | -24.50 | NANOG (Nanog homeobox) | protein interactions | 79923 | 225 | 77 | 17029 | 2761 |
USP7,TXN,TRERF1,CHERP,SUZ12,EIF3D,MAGED1,HNRNPUL2,KIAA1551,CSNK2A1,TWF2,RBM4,SAP130,MTA1,RAD23B,USP34,ZNF524,SNRPB,CIRBP,RPL38,DDX20,EDF1,PBRM1,MCM2,TXNL4A,LUC7L,MBD3,ERC1,USP21,DOT1L,SUPT16H,AMZ2,SUGP1,TPP2,SASS6,SINHCAF,SMAD4,TUBB,PRPF38B,NCOR2,MRPL9,TOR3A,CENPF,TRMT6,TIA1,LETMD1,ARGLU1,PDCD7,CDC73,ARID1B,RBM17,PSMD2,SMC3,HUWE1,SSBP3,NAA50,PRC1,RTCB,SAMD4B,DDX24,RB1CC1,MTA2,USP42,BCLAF1,PCGF1,XRCC5,COMMD3-BMI1,CCDC86,NSF,GPS2,KHSRP,ZMIZ1,CFAP20,ECPAS,HNRNPDL,ANAPC4,DDB1 |
| 2.309e-11 | -24.49 | GO_NUCLEUS_ORGANIZATION | MSigDB lists | GO_NUCLEUS_ORGANIZATION | 127 | 50 | 17377 | 2626 |
CHMP2A,PDCD6IP,NUP188,RAE1,TOR1AIP1,NUP54,AGFG1,CCNB1,ETS1,NUP205,LMNA,GOLM1,UBXN2A,RRN3,AHCTF1,NUP210,NEK6,BANF1,NUP107,NSFL1C,NUP153,TARDBP,POLR1B,NUP85,SEH1L,SRPK2,ANKLE2,PLK1,TOR1AIP2,NUP155,CHMP2B,KDM3A,LEMD2,PPP2CA,CHMP4A,OSBPL8,HIPK2,UBXN2B,CEP55,PML,TBPL1,NUP62,HMGB2,CHMP4B,VPS4A,REEP4,CHMP7,CCNB2,AAAS,TMEM33 |
| 2.367e-11 | -24.47 | GO_METAPHASE_PLATE_CONGRESSION | MSigDB lists | GO_METAPHASE_PLATE_CONGRESSION | 41 | 25 | 17377 | 2626 |
CHMP2A,PSRC1,PDCD6IP,CENPF,CUL3,CDCA8,KIF2C,CDC23,CCNB1,CHMP2B,BECN1,RAB11A,KIFC1,CHMP4A,KIF18A,KIF14,CEP55,CDCA5,FAM83D,CHMP4B,KIF22,VPS4A,RRS1,CHMP7,SEH1L |
| 2.375e-11 | -24.46 | GSE9006_TYPE_1_DIABETES_AT_DX_VS_1MONTH_POST_DX_PBMC_UP | MSigDB lists | GSE9006_TYPE_1_DIABETES_AT_DX_VS_1MONTH_POST_DX_PBMC_UP | 188 | 65 | 17377 | 2626 |
SART1,GPR132,ADAM10,XAB2,TSC22D3,GLUD1,KIF2C,DAZAP2,SAFB2,PABPC4,FARSA,NAPG,RAB8A,ATP2A2,CDC37,PPIF,NRAS,MAP4K4,MRPL12,SMU1,AMDHD2,GLOD4,BRMS1,CDCA4,STT3A,HNRNPR,TBL3,CORO1C,SAFB,DNAJC17,SH3GLB2,FKBP5,RTN3,PPIB,EWSR1,MAPRE1,CDT1,AGPAT3,RPN1,NDUFV1,BANF1,ARL6IP1,ANP32A,RBM3,AHCY,OSTF1,COPS7B,TMEM160,RBM42,PRKDC,WDR18,ABCF1,MFN2,SEC31A,TPD52L2,GALNT2,ELMO1,ODF2,YWHAZ,HMGB2,GPI,EHD4,RBBP4,CDK2,EGLN1 |
| 2.375e-11 | -24.46 | GSE3337_4H_VS_16H_IFNG_IN_CD8POS_DC_UP | MSigDB lists | GSE3337_4H_VS_16H_IFNG_IN_CD8POS_DC_UP | 188 | 65 | 17377 | 2626 |
HNRNPAB,AGRN,UCK2,TMEM97,ENSA,NANS,PRNP,NEK6,EIF4A3,SIVA1,SLC44A1,SRI,MRPL34,RNASEH2A,METTL9,COPS8,PPIF,LARS,BIRC3,ANKRD33B,CRNKL1,RNPS1,ATP6V0A1,PFKFB3,EDF1,TMEM147,MCM2,GAR1,MAT2A,PRIM1,MRPL2,IDE,HSPA4,MAFK,GADD45B,SNRPG,PSMC1,ZC3HC1,CSNK1D,GALK1,GADD45G,CDT1,SRGN,RRM1,CDK11B,METTL3,LMNA,CHKA,SUB1,MCM5,BUD31,FOXN2,STAT3,NUP85,PPA1,ABCC1,EIF3L,POLR2I,TK1,NASP,TNFAIP3,LDHA,GOSR1,NUP62,RUVBL2 |
| 2.406e-11 | -24.45 | MORF_NPM1 | MSigDB lists | MORF_NPM1 | 159 | 58 | 17377 | 2626 |
RPS2,RPLP2,PHB2,EIF3D,SUMO2,NACA,RPL15,COX4I1,UBE2I,PARK7,RPL11,RPL23A,RPL17,YBX1,RPL19,STRAP,PABPC1,PCBP2,CFL1,EEF1D,CCT2,RPL29,HMGN1,RHOA,RPL35,SNRPB,RPS10,RPL6,LDHA,RNPS1,JTB,RPL8,RPL38,RPS24,USP22,RPL27A,EIF4G2,H2AFV,RPS9,EIF3H,HMGN2,CBX3,RPL37,GNAS,NAP1L1,RPL32,HINT1,RPS27A,RPS14,RPLP1,UQCRH,YWHAZ,ACTB,BTF3,COPS6,FAU,OAZ1,TUBB |
| 2.450e-11 | -24.43 | MORF_PRKAR1A | MSigDB lists | MORF_PRKAR1A | 135 | 52 | 17377 | 2626 |
SEPHS2,COX5B,KARS,UGP2,DYNLL1,SUMO2,RAC1,DCTN2,ENSA,STARD7,COX4I1,RAB6A,SDHA,BCAP31,MBD4,NDUFA2,ARPC5,ARF5,MTA1,BANF1,RAD23B,CAPZA1,HADHB,RPN2,CYC1,AHCYL1,SLC35A1,EEF1D,TMED2,KDELR1,EBAG9,SP3,WBP2,JTB,GMFB,SSR2,GORASP2,RAB1A,PRPSAP1,RAB5B,DAP3,PDCD6,NSF,SETD3,COX7A2L,COX8A,PPP1R11,MDH1,YWHAZ,CLN3,ATP6V0E1,MYL12B |
| 2.531e-11 | -24.40 | GO_RIBOSOME_BIOGENESIS | MSigDB lists | GO_RIBOSOME_BIOGENESIS | 285 | 87 | 17377 | 2626 |
SART1,DDX47,NOP2,RPLP2,EBNA1BP2,BRIX1,RPL11,RPL23A,KRR1,PA2G4,RRN3,NOL11,EIF4A3,NVL,UTP18,ZNHIT6,EXOSC1,NOC2L,RPF2,FTSJ3,RPP25,RPL29,EXOSC6,RPL35,AATF,NOL8,RPL38,UTP3,GAR1,MAK16,LSG1,RPS9,RPSA,NSA2,RPL37,LSM6,RPS27A,NIP7,RPS14,TBL3,RPLP1,RNASEL,RRS1,FAU,PDCD11,RPS26,NMD3,CSNK1D,RPS15,RPS2,RPL15,PNO1,RRP36,DDX56,EXOSC7,RPL17,DDX31,RPL19,GEMIN4,FBL,ERI3,MRPL11,NSUN4,PPAN,DDX28,NOA1,TEX10,WDR18,RPS10,UTP15,GTPBP4,RPL8,RPL6,RPS24,BMS1,EXOSC9,EIF2A,RPL27A,ABCF1,TSR2,RPL36,UTP20,TSC1,RPL32,CDKN2A,BYSL,DDX52 |
| 2.654e-11 | -24.35 | TCTN3 (tectonic family member 3) | protein interactions | 26123 | 315 | 98 | 17029 | 2761 |
NDUFA5,NDC1,DDX47,PRKCSH,TMEM41B,TOR1AIP1,GPR89A,COPE,TMEM109,TAP1,TM9SF3,ABCB10,CLCC1,IKBIP,LCLAT1,BCAP31,SSR1,SEC11A,ATP2A2,SAR1A,RPN2,CISD2,TAP2,LMAN1,PDIA6,LRRC59,RHBDD2,ANKLE2,ATP13A1,RAB7A,ATP6V0A1,TOR1AIP2,ESYT1,KRTCAP2,RAB1A,ALG3,TMEM184C,DNAJC10,TMEM41A,ATP1A1,DDOST,SURF4,ITGB1,ATP6V0C,NCLN,REEP4,CHPT1,RTN3,AAAS,TMEM33,PPIB,NDUFV2,NDUFS1,CDS2,TMX3,RACGAP1,REEP5,MFSD10,TFRC,NUP205,EBP,GSTK1,RPN1,NUS1,VMP1,DAD1,SLC35B4,EI24,ATP6V0A2,YIF1B,NDUFS8,SLC12A2,TMX1,TMED2,PREB,NIPSNAP1,MLEC,PIGT,SIGMAR1,NSDHL,ERO1A,ACSL3,POLR2A,YIF1A,DERL1,MAGT1,ORMDL2,OSBPL8,ERGIC3,PML,PGRMC1,SAMD8,SPCS3,SMPD4,PLOD3,IDH3B,PTDSS1,APOL2 |
| 2.670e-11 | -24.35 | KANG_DOXORUBICIN_RESISTANCE_UP | MSigDB lists | KANG_DOXORUBICIN_RESISTANCE_UP | 50 | 28 | 17377 | 2626 |
GINS1,POLA2,PLK1,TK1,HJURP,NQO1,FOXM1,ASPM,RAD51AP1,PBK,TPX2,MKI67,RRM1,CDCA8,RRM2,NUSAP1,CDC6,NCAPG,FANCI,ASF1B,OIP5,ATAD2,BIRC5,PRC1,HMGB2,CENPM,ABCC1,POLQ |
| 2.670e-11 | -24.35 | ISHIDA_E2F_TARGETS | MSigDB lists | ISHIDA_E2F_TARGETS | 50 | 28 | 17377 | 2626 |
RFC3,TK1,CDT1,PTTG1,DBF4,MKI67,RRM1,RRM2,SLBP,NUSAP1,AURKB,SMC2,CCNB1,ANLN,STMN1,ASF1B,RPA1,PRIM1,CDKN2C,RB1,CCNA2,PCNA,DUT,PRC1,KPNA2,HMGB2,CDK2,CCNB2 |
| 2.824e-11 | -24.29 | TMEM17 (transmembrane protein 17) | protein interactions | 200728 | 400 | 117 | 17029 | 2761 |
WASF2,EXOC3,NDC1,COPA,RAB11B,TOR1AIP1,ANK3,GPR89A,COPE,SLC29A1,CLCC1,AP1B1,SLC20A1,LYN,STAM,KTN1,BCAP31,DST,SEC11A,ADCY9,RPF2,SCAMP4,LMAN1,AHCYL1,TFG,CNNM3,RHBDD2,SCYL3,TMEM9,GCC1,ABCC5,EBAG9,WDR41,ANKLE2,USO1,TMEM115,AKT2,GOPC,RAB7A,MAP4K4,LRBA,MTMR6,NUP155,GORAB,ERBIN,ESYT1,AP4E1,STX16,RAB5B,TOLLIP,CLNS1A,NSA2,ATP1A1,WDR11,ITGB1,FTSJ1,BTF3,SCARB1,DVL1,AP2S1,LRP8,PARD3,NUMB,SLC12A7,PKP4,SCAMP3,GGA1,SCYL1,VPS45,RAB23,CDCA3,EPN1,ARFIP2,NCKAP1,NOTCH2,PDXDC1,SCYL2,TFRC,HLA-A,FZD6,DDRGK1,PTPN2,ADD3,SLC1A4,NDUFS8,SLC12A2,FAM171A1,TMX1,ABCC1,PREB,CYFIP1,SNX2,NSDHL,ATP2C1,ACSL3,GORASP2,GOSR1,APPL1,MARK2,SMAP2,YIF1A,SEC31A,SLCO4A1,SLC19A1,PLD3,HGS,OSBPL11,SEC23IP,OSBPL8,SNAP23,EXOC4,SMPD4,SPCS3,YWHAH,NIPSNAP2,ZC3HAV1,ESYT2 |
| 2.885e-11 | -24.27 | MARTINEZ_RESPONSE_TO_TRABECTEDIN_DN | MSigDB lists | MARTINEZ_RESPONSE_TO_TRABECTEDIN_DN | 263 | 82 | 17377 | 2626 |
LUZP1,UBN1,SLC2A1,UCK2,C5orf30,CSNK2A1,BCL2L1,SEC16A,MAPK14,GGPS1,BIRC2,MEAF6,DLG5,CYHR1,PRKD3,PCNA,CCNA2,MTMR4,DNAAF2,SRSF4,RAD23B,TARDBP,PTPRK,SRPK2,CDC5L,PLK1,GOPC,DDX20,USP22,CDC23,RAB1A,ANLN,STK17B,EML4,MAT2A,EIF3A,RAD54B,EPB41,MAP3K4,MID1IP1,CORO1C,CEP55,OGT,FBXL3,HDAC2,UBE2D3,HSPH1,B4GALT5,RAB6A,THRAP3,CRLF3,CFLAR,MCTS1,RBM17,DTL,ARHGEF2,FBXL7,PTGES3,GTF2H2,GCC2,STAU1,PRIM2,NET1,BTAF1,ACSL3,RCOR1,ADSL,EIF2A,KIF11,FADD,PHF6,XRCC5,FNTA,CDC27,RBM25,MFAP1,DCK,WNT5B,SRSF3,RNF14,UBE2C,FAF1 |
| 2.902e-11 | -24.26 | HAMAI_APOPTOSIS_VIA_TRAIL_UP | MSigDB lists | HAMAI_APOPTOSIS_VIA_TRAIL_UP | 546 | 141 | 17377 | 2626 |
PLXNC1,ZNF107,USP48,BRIX1,MYEF2,BIRC2,MBD4,KRR1,NSRP1,ATG3,PDS5B,TCEA1,CDC5L,USO1,RAD51AP1,PBK,SLC16A7,MKI67,KIF15,WDHD1,BRCA1,SMC2,PBRM1,ANLN,EIF3A,OPTN,KRIT1,RAD18,WDR11,LUC7L3,U2SURP,ITGB1,BAZ1B,ADAM9,FBXL3,FAM208A,MYL12B,HDAC2,HSPH1,RECQL,PRPF38B,ZCCHC9,CENPF,KIF23,ASAH1,TOP2B,PRPF39,RLF,RAPGEF6,NDUFS4,FKBP1A,C1GALT1,SMC3,EIF2S2,MSH2,KNTC1,SRSF11,GCC2,AGGF1,RB1CC1,ITM2A,BCLAF1,EIF2A,FXR1,MTR,APPL1,EPRS,NAP1L1,GOLGA4,PCM1,MYO9A,BCCIP,ATXN3,GGNBP2,FAM208B,RWDD1,SUZ12,CAST,NUF2,KTN1,CHD1,PAIP1,ZNF302,IARS,STRBP,KIF14,UCHL5,ZCCHC2,BCAP29,CEP63,NUSAP1,DCLRE1C,DNAJA1,CHMP2B,RAD54B,HIPK2,STAT1,XRCC4,ZBTB11,ZNF146,POLQ,GOLIM4,DEPDC1,DBF4,SMC6,BLM,RMI1,KIF5B,RBM17,ADD3,DNAJC8,PDCD10,CWC27,PTEN,PPIG,ORC3,CREB1,GTF2H2,MYO5A,SMC4,RPAP3,PHF20L1,POLK,SNX2,ASPM,LLPH,PPWD1,KIF11,ZNF407,CBX3,KIF18A,ATAD2,ZHX1,OSBPL8,MFAP1,MAPK6,BBX,ACADM,TATDN1,RPS6KC1,IFI16 |
| 2.940e-11 | -24.25 | GO_MITOCHONDRIAL_ENVELOPE | MSigDB lists | GO_MITOCHONDRIAL_ENVELOPE | 612 | 154 | 17377 | 2626 |
COX15,MTX3,NDUFB6,MRPS15,UQCR10,MCCC1,ABCB10,BECN1,MRPL19,PARK7,SLC25A37,PRNP,TIMM23,GOT2,SLC44A1,HADHB,NDUFB9,CISD2,MRPL32,TIMM50,BAK1,MRPL12,MRPL43,SLC25A22,MCL1,SLC25A5,FOXRED1,STOML2,TIMM13,MRPL27,MPV17,COX5A,UQCRH,CLU,MRPL13,SLC25A33,COX5B,NDUFV2,MRPL9,PHB2,NDUFA4,COX4I1,CYCS,PSEN1,NDUFS7,NDUFS4,BDH1,BCL2,CYC1,MRPL48,MRPL40,ALDH18A1,MRPL21,NIPSNAP1,TIMM8B,NOA1,PGS1,ACSL3,MRPL16,MTX1,TOMM40,SFXN5,CYB5A,AKAP1,CAT,SDHB,COX7A2L,MRPL3,NDUFA5,IMMT,ATXN3,TOMM20,SUCLG1,NDUFAF2,RAF1,MDH2,MRPL39,BCL2L1,SLC25A44,SNN,LYN,SDHA,MOAP1,MRPL50,CSDE1,MRPL34,MRPS27,PARL,MAVS,APOOL,ATF2,TMEM14C,HTRA2,ACSL5,PPIF,COQ10B,CPOX,VDAC2,NLN,OGDH,NDUFA7,VDAC1,NDUFB1,MRPS14,TAZ,GFER,CHCHD3,ANKZF1,MRPL2,DAP3,MRPL55,TIMM17A,TOMM6,CHCHD1,NDUFA11,SLC25A39,CDS2,NDUFS1,MRPL42,MRPS26,LETMD1,SLC25A12,SLC25A43,SLC25A36,GSTK1,NDUFV1,COQ4,NDUFA2,NDUFB4,CRAT,MRPL54,NDUFS8,MRPL11,STAT3,NDUFA3,MTX2,RNF5,SLC25A1,TIMMDC1,TMEM126B,MRS2,ABCF2,MRPS10,RHOT1,RHOT2,GUF1,CHCHD6,SH3GLB1,MFN2,COX8A,SLC25A19,ACAT1,NDUFS5,HIGD2A |
| 2.951e-11 | -24.25 | GO_ESTABLISHMENT_OF_PROTEIN_LOCALIZATION_TO_ORGANELLE | MSigDB lists | GO_ESTABLISHMENT_OF_PROTEIN_LOCALIZATION_TO_ORGANELLE | 346 | 100 | 17377 | 2626 |
POLA2,TOMM20,NUP188,SYS1,MTX3,RPLP2,TSC2,VTI1A,BECN1,RPAIN,RPL11,RPL23A,MOAP1,SNUPN,TIMM23,NUP107,TNPO2,F2R,GCC1,TIMM50,SRP72,RPL29,RPL35,NRAS,SEC61B,RAB7A,RPL38,NUP155,NUTF2,RPS9,RPSA,OPTN,RPL37,HSPA4,TIMM13,PEX5,CHMP4A,SEC61A1,RPS27A,TIMM17A,RPS14,ARNTL,RPLP1,KPNA2,CHMP4B,FAU,SMURF1,MAPK1,RPS26,LONP2,POT1,RPS15,RPS2,SEC61G,PHB2,RAE1,NUP54,RPL15,RAB6A,RAB11A,VPS25,NUP205,LMNA,RPL17,FBXO7,TNPO3,H2AFY,RPL19,STAT3,NUP85,MTX2,TGFB1,NAGPA,PPP3CA,GCC2,TIMM8B,TNFAIP3,RPL8,RPL6,RPS10,RPS24,PACS1,MTX1,TOMM40,PTTG1IP,RPL27A,MAPK3,MFN2,RPL36,SCARB2,HGS,KPNA4,GOLGA4,KPNA1,RPL32,PML,NUP62,RUVBL2,TOB1,IPO4 |
| 2.972e-11 | -24.24 | M Phase | REACTOME pathways | R-HSA-68886 | 308 | 97 | 10287 | 1696 |
NDC1,H2AFZ,NUP188,PTTG1,ENSA,CSNK2A1,NUF2,KIF2C,CCNB1,MIS12,PSMD1,AHCTF1,NUP210,PSMA6,NEK6,LPIN2,NUP107,PDS5B,ANAPC7,NUP153,SEH1L,ANKLE2,PLK1,USO1,PSMA8,TAOK1,PSMB7,NUP155,AURKB,SMC2,CDC23,RAB1A,PSMB9,H2AFV,CENPU,KIF2A,PPP2CA,CDC16,PPP2R5A,DSN1,RPS27A,PSMD8,PSMD3,H2AFX,H3F3A,MAPK1,PSMC1,PPP2R2D,AAAS,MAPRE1,GORASP1,RAE1,CENPF,CDCA8,NUP54,KIF23,PMF1,SPDL1,PSMD9,NCAPG,NUP205,LMNA,FBXO5,RB1,PSMD2,SMC3,KMT5A,BANF1,KNTC1,CENPM,MCPH1,NUP85,SMC4,NUDC,NEK7,PSMA1,ANAPC2,GORASP2,RANGAP1,PSMB3,MAPK3,PSMC4,MASTL,LEMD2,KIF18A,CDC27,GOLGA2,BIRC5,CDCA5,NUP62,CENPT,NDE1,CCNB2,UBE2C,ESPL1,NUP58,ANAPC4 |
| 3.001e-11 | -24.23 | regulation of transcription, DNA-templated | biological process | GO:0006355 | 3731 | 697 | 17256 | 2622 |
ZBTB10,KDM4A,HEXB,XIAP,CCNL2,EDRF1,ZNF275,CDK5,USF1,PSMD1,CIPC,THAP4,DNM2,CRY2,FNIP2,ECD,SENP1,PLK3,ZNF672,ZNF559,AATF,GABPA,EHMT1,WDHD1,MIER2,TOPORS,ARF4,BRMS1,BOLA3,SMAD2,RPS27A,ZNF689,AXIN1,PRDX5,OGT,VIPAS39,RNASEL,TRIM52,TFDP2,SMAD1,E2F2,ZNF75A,PDCD4,ZNF720,SSRP1,HIVEP3,DHX9,EZH1,EIF2AK4,PSMD9,CDC73,MCTS1,DDRGK1,TFAP4,MEGF8,PHF14,ZNF326,FOXN2,MYDGF,NUP85,IFRD1,ETV3,FOXK1,RB1CC1,ZMYND11,MTA2,MYBL2,BCLAF1,CBFA2T2,ELK1,PDLIM1,ETS2,SETD3,CNOT6,SGF29,EGLN1,ZNF207,RHOG,ZNF296,KARS,SARNP,TRERF1,IVNS1ABP,UBR2,PTTG1,WDTC1,CREBL2,ZNF267,INO80E,SAFB2,RCOR3,TCF19,APP,AHCTF1,ZNF420,SP100,ZKSCAN1,MTA1,GMEB1,NUP107,ZNF226,MAVS,ATF2,RBM15,ZC3H3,RPRD1B,CGGBP1,CPNE1,PSRC1,POLR2L,EID1,KAT7,WBP2,E2F3,HTATIP2,MEF2D,DDX17,TAF2,PPP2CA,CHCHD3,HIPK2,TICAM1,FUS,ZBTB11,LRP8,USP13,COMMD10,ZNF786,ZNF445,ZFP91,HABP4,TRAK1,JMJD6,GMCL1,ABHD14B,WDR5,ETS1,NEXMIF,ZNF92,ZBTB45,PSMD2,SUV39H2,PPP1R8,PRDM4,ZNF260,ZNF710,GTF2H2,MED22,PDPK1,PPP3CA,TNFAIP3,ZNF512,ZP3,PICALM,ZNF862,ZNF180,KEAP1,GPS2,PITX1,LRPPRC,PML,HMGB2,CD81,PARP10,IGBP1,USF2,YWHAH,THAP5,FAF1,THOC1,AGRN,AAMDC,GPBP1L1,TRIM11,CSNK2A1,SND1,BIRC2,CREM,PRNP,LIN9,TET3,PCNA,GLIS2,ZNF639,ETV6,PIK3R2,NOC2L,MYBL1,MTPN,CCAR1,RYBP,PTPRK,PLK1,SP3,CELSR2,RBX1,PBXIP1,BAZ2A,ZBED5,MRPL12,EZR,CDC6,UBE2V1,LRP5,PBRM1,EAF2,BRCA1,USP21,TONSL,CHD3,ZNF367,E2F4,DVL1,ZNF45,BEND6,FAM208A,ZNF564,FUBP1,LZTR1,PHB2,CENPF,CTCF,CHCHD2,CDK13,DNAJB1,PPP3CB,RLF,ASXL2,CNOT11,CRLF3,ARID1B,LRRC14,SUB1,RB1,MLX,MED8,MBD2,SSBP3,ZNF746,CTR9,TIMELESS,MDFIC,AFF1,ICE2,MAML1,PREB,TRAPPC9,LDB1,UTP15,KRAS,RTF1,ZNF761,NFATC2IP,IRF5,ZNF174,PSMC4,RXRB,NLRC5,TBPL1,PRMT7,RUVBL2,USP7,CYLD,TRAF7,ARID2,FOXM1,DYNLL1,ZNF416,DUSP22,PCBP1,COMMD8,ZNF121,VAV1,CSDE1,NRF1,ZBTB21,PSMA6,ZNF473,MDM2,KMT5C,ZNF302,PIN1,TARDBP,STRAP,SAP30L,ZNF583,DVL2,KDM3B,ZNF780B,PSMA8,BTG2,PPIE,NFATC2,KDM1B,ZNF700,SCAP,RBL1,MAFK,PSMD3,ZNF436,UHRF2,DNAJC17,NCOA1,H3F3A,SMAD4,ZNF146,BCL2L12,SLC30A9,CTDP1,MTERF1,DAP,CDT1,AGO2,ARID5A,GTF3A,HMGN3,NKRF,CDK11B,PAGR1,FZD6,PTPN2,IRF4,SS18L1,RBM15B,RPRD1A,RHOA,HMGN5,BTAF1,PRKDC,ZNF202,ZMYM5,PCGF1,TRIM26,BIRC5,TWSG1,L3MBTL3,TFE3,CDCA7L,BBX,E2F1,PKD2,RBPJ,TAF12,NR2F2,HIPK3,IFI16,TXN,H2AFZ,MAX,ZNF496,TSC22D3,CXXC1,UBE2I,COMMD6,PARK7,MYEF2,GLMP,PA2G4,NOL11,FIZ1,ZNF200,TAF5L,SMARCE1,DNMT1,ZNF800,CDC5L,SRSF10,ZNF524,KLF10,ELOA,DDX20,AURKB,USP22,CBFB,ZMYM3,IWS1,DOT1L,HHEX,BRD2,PSMD8,RPS14,BTF3,ARRB2,TRAF5,CCDC59,HDAC2,PTOV1,DDX58,HSPH1,EWSR1,POLR2K,PRKAA1,NOTCH2,PMF1,SUPT7L,PSEN1,ZNF518A,ZNF79,VPS25,JMY,CNOT3,YY1AP1,CFLAR,LHX8,KLF16,HDAC7,TNRC18,EEF1D,TERF2,PHF10,ZNF84,ELL2,ZNF574,USF3,EXOSC9,ADRB2,ARID1A,C9orf40,KDM3A,MAP2K2,PSMB3,PHF6,XRCC5,CAT,PFDN5,ZNF777,SERTAD2,EPOP,ZFP92,RBMX,QARS,MED15,CEBPG,PPP3R1,PIAS2,YY1,MAP3K5,RNF14,CDK2,CDKN2A,ZNF511,DNMT3A,ATXN3,RWDD1,ZBTB37,RPS6KA1,RAF1,SUZ12,MAGED1,TERF2IP,SPINDOC,CCNA2,ZNF75D,SHC1,KDM2A,UCHL5,LPIN2,CDKN1B,CDK12,SAP30,BRD4,ERF,DRAP1,CUL3,ELP4,EDF1,H2AFV,PSMB9,TRIM28,ERC1,CENPU,PRDM11,SUPT16H,VEZF1,ZNF282,HINT1,CERS6,SAFB,STAT1,H2AFX,ATF6,TRIM32,BEND3,EYA2,ATMIN,RHEBL1,POU3F2,NCOR2,DEPDC1,MECP2,TCF3,MYNN,ARGLU1,BLM,POFUT1,FOXO3,HMG20A,MAD2L2,WWP2,GTF2F1,CCNK,PTEN,ELP5,CARF,CITED2,CREB1,CNOT6L,NCOA2,TSHZ1,ZFP64,KAT2A,ILF3,RFXANK,KLF6,COMMD4,FADD,POLR2A,CBX3,PRDX3,ZHX1,TFDP1,KHSRP,DDX5,BRWD3,TAF6,PURA,FAM83G,RORB,CCNC,ZBED3,ZNF76,IER2,NOP2,HNRNPAB,UBN1,KMT2E,PTP4A3,ZNF107,SIRT2,TAF6L,COMMD5,MAPK14,SNAPC4,ZNF696,JAZF1,PHTF1,SRI,ZBTB22,TCEA1,OGG1,ARID4A,CARM1,TRIM14,ELOF1,DEAF1,TRIM8,NCK1,VHL,RIOX2,RRM2,SOX4,KMT2C,ASF1B,UBTF,PAF1,BRWD1,PQBP1,BAZ1B,ZNF268,CHEK2,CLU,PSMC1,UBE2D3,PPP1R12A,ZNF768,NACA,CIB1,MED13L,MEF2A,THRAP3,SRRT,TTF1,LYAR,NFATC3,ZNF449,MED10,ZNF335,BUD31,YBX1,ACAD8,MCPH1,ZNF189,HP1BP3,VOPP1,CREG1,ERLIN1,CIC,RPL6,PSMA1,EIF2A,SLTM,DAPK3,CAND1,NFIL3,NUP62,ZFP90,RBBP4,HNRNPDL,TOB1,N4BP2L2,SMARCD1,ADNP2,ZBTB24,MBD1,TCF12,ASH1L,MPHOSPH8,SMARCA4,PLAGL2,NSD3,IRF3,ORC1,CHD1,MXD1,MEAF6,HNRNPA2B1,SAP130,RRN3,AKAP8,CHTOP,F2R,UTP4,ZNF770,RLIM,CHP1,MOSPD1,POU2AF1,FAM172A,ZNF500,RNF25,PSMB7,PCGF6,ATXN1,BOLA1,GLO1,ERBIN,MBD3,ZNF317,TAB2,STAT6,TULP3,ARNTL,AKNA,SMURF1,BRD9,MAPK1,CBX4,NAT14,DNAJC2,ZNF316,EYA1,SCYL1,KLF13,PAWR,MXD4,FBXO5,KMT5A,PELO,ANP32A,BRD7,ARHGEF2,H2AFY,STAT3,SAMD4B,TGFB1,PHF20L1,DCAF6,HMGN1,PSPC1,MIER1,RCOR1,PRMT2,MEN1,ZNF407,CDK11A,MAPK3,TFEB,HSPA1B,CNOT9,LEMD2,ATAD2,KMT2B,ZRANB2,CENPT,ZMIZ1,HRAS,TERF1 |
| 3.035e-11 | -24.22 | Retinoblastoma (RB) in Cancer | WikiPathways | WP2446 | 88 | 40 | 5312 | 837 |
H2AFZ,RAF1,CDT1,RRM1,ORC1,CCNB1,STMN1,RPA2,RB1,MDM2,PCNA,SMC3,CCNA2,CDKN1B,CDC25B,DNMT1,MSH6,SAP30,RFC3,PRKDC,E2F3,RABIF,RRM2,SMC2,PRMT2,ANLN,PRIM1,RPA1,POLE,CCDC6,DCK,TFDP1,E2F1,HMGB2,TFDP2,RBBP4,CCNB2,CDK2,E2F2,FAF1 |
| 3.092e-11 | -24.20 | GSE17721_LPS_VS_POLYIC_12H_BMDC_UP | MSigDB lists | GSE17721_LPS_VS_POLYIC_12H_BMDC_UP | 189 | 65 | 17377 | 2626 |
SRM,MPHOSPH8,IVNS1ABP,MOGS,CLCC1,SLC20A1,MIEN1,UBLCP1,CSDE1,RRN3,NOL11,MECR,NOC2L,HADHB,ECD,RNF26,LRRC59,USP34,BOLA1,NUTF2,USP21,SRSF1,PON2,HSPA4,STT3A,SPRYD4,GAS2,CHID1,PDF,SEPHS2,TM9SF4,CHCHD2,XPO7,AP3S1,CNOT3,PNO1,LRRC14,CEP104,IRF4,NFATC3,BDH1,ANP32A,TAGLN2,ERI3,FDFT1,ZFP64,RHOA,ADAM17,TMEM39A,NOA1,CYFIP2,MPG,EIF4G2,ZDHHC3,POLR2A,CAND1,UTP20,CAT,SEC31A,EPRS,CTBS,ACLY,FAM122A,NUP62,DDB1 |
| 3.254e-11 | -24.15 | hydrolase activity, acting on acid anhydrides | molecular function | GO:0016817 | 892 | 210 | 17224 | 2647 |
RAB14,DDX47,ABCC10,YTHDC2,TAP1,DHX8,ABCB10,KIF2C,ATP5PF,KIFC1,RAB8A,RAP1A,CDC42,EIF4A3,RAB35,XRCC2,RAB4A,ATP13A3,DNM2,KIF22,EIF5,ABCC5,SNRNP200,RHOBTB3,NRAS,SEPT9,KIF15,DDX20,ARHGDIB,PBRM1,MCM2,RFC2,RAB5B,LSG1,RAB22A,DHX15,RAB2B,GINS4,ARF4,RHEB,SEPT1,RAD18,KIF18B,CHD3,MYO18A,ATP6V0C,CLU,VPS4A,NUDT11,PSMC1,LONP2,ATP6V0E1,DDX42,DDX58,HSPH1,RECQL,MUT,RHOC,CHTF18,GSPT2,DHX9,RAB23,KLC1,KIF23,TOP2B,RAB6A,MYL6B,TMEM250,DDX56,SMC3,MCM5,KIF13B,EFTUD2,MSH2,ATP6V0A2,GNAI2,ATP6V0D1,PPA1,ABCC1,DDX28,NTPCR,NOA1,DHX29,NUDT4,GTPBP4,SEPT8,KRAS,RIT1,SEPT7,EIF4H,ABCF1,CCT8,RHOB,PSMC4,XRCC5,GNAS,NSF,ATP5F1A,RUVBL2,RBBP4,MYO9A,NUDT3,RHOG,ABCA3,RAB11B,DYNLL1,CHD1L,RAC1,PMS2,OLA1,MYH9,RRAGC,SMARCA4,EFL1,ATP6V1B2,GNB2,CHD1,RAB21,ATP6V0B,ATP2A2,RALB,PIN1,KIF14,DUT,SEPT11,TAP2,AQR,DNAL4,DCTN1,ATP6V1G1,ENPP4,RFC3,ATP13A1,RAB7A,ATP6V0A1,RAB1A,DHX57,RAD54B,DDX17,KIF2A,RAD51C,IDE,ATP1A1,HSPA4,ACYP1,RAB24,DHX16,PPA2,CANT1,XRCC3,ABCA1,DYNC1LI2,RAD51D,TUBB,RHEBL1,POLQ,KIF3B,SHPRH,TWNK,TOR3A,DCTN2,MYO9B,ARF1,ATP5F1B,BLM,IFT27,RAB11A,GFM2,WRNIP1,GTPBP3,KIF5B,STARD9,ARF5,ABCD1,DDX31,GTF2H2,MSH6,MYO5A,GINS1,RHOA,DDX24,HELB,BTAF1,ABCF2,ATP2C1,TUFM,BMS1,ATP5MF,RHOT1,DDX39A,GUF1,KIF11,MACF1,RHOT2,HSPA1B,MYO1F,DDX23,MFN2,RAB18,GNA12,UPF1,ATP6V1D,KIF18A,ATAD2,ATP5MC3,DDX5,ASNA1,ATP6V1C1,HRAS,DDX52 |
| 3.254e-11 | -24.15 | hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | molecular function | GO:0016818 | 892 | 210 | 17224 | 2647 |
RAB14,DDX47,ABCC10,YTHDC2,TAP1,DHX8,ABCB10,KIF2C,ATP5PF,KIFC1,RAB8A,RAP1A,CDC42,EIF4A3,RAB35,XRCC2,RAB4A,ATP13A3,DNM2,KIF22,EIF5,ABCC5,SNRNP200,RHOBTB3,NRAS,SEPT9,KIF15,DDX20,ARHGDIB,PBRM1,MCM2,RFC2,RAB5B,LSG1,RAB22A,DHX15,RAB2B,GINS4,ARF4,RHEB,SEPT1,RAD18,KIF18B,CHD3,MYO18A,ATP6V0C,CLU,VPS4A,NUDT11,PSMC1,LONP2,ATP6V0E1,DDX42,DDX58,HSPH1,RECQL,MUT,RHOC,CHTF18,GSPT2,DHX9,RAB23,KLC1,KIF23,TOP2B,RAB6A,MYL6B,TMEM250,DDX56,SMC3,MCM5,KIF13B,EFTUD2,MSH2,ATP6V0A2,GNAI2,ATP6V0D1,PPA1,ABCC1,DDX28,NTPCR,NOA1,DHX29,NUDT4,GTPBP4,SEPT8,KRAS,RIT1,SEPT7,EIF4H,ABCF1,CCT8,RHOB,PSMC4,XRCC5,GNAS,NSF,ATP5F1A,RUVBL2,RBBP4,MYO9A,NUDT3,RHOG,ABCA3,RAB11B,DYNLL1,CHD1L,RAC1,PMS2,OLA1,MYH9,RRAGC,SMARCA4,EFL1,ATP6V1B2,GNB2,CHD1,RAB21,ATP6V0B,ATP2A2,RALB,PIN1,KIF14,DUT,SEPT11,TAP2,AQR,DNAL4,DCTN1,ATP6V1G1,ENPP4,RFC3,ATP13A1,RAB7A,ATP6V0A1,RAB1A,DHX57,RAD54B,DDX17,KIF2A,RAD51C,IDE,ATP1A1,HSPA4,ACYP1,RAB24,DHX16,PPA2,CANT1,XRCC3,ABCA1,DYNC1LI2,RAD51D,TUBB,RHEBL1,POLQ,KIF3B,SHPRH,TWNK,TOR3A,DCTN2,MYO9B,ARF1,ATP5F1B,BLM,IFT27,RAB11A,GFM2,WRNIP1,GTPBP3,KIF5B,STARD9,ARF5,ABCD1,DDX31,GTF2H2,MSH6,MYO5A,GINS1,RHOA,DDX24,HELB,BTAF1,ABCF2,ATP2C1,TUFM,BMS1,ATP5MF,RHOT1,DDX39A,GUF1,KIF11,MACF1,RHOT2,HSPA1B,MYO1F,DDX23,MFN2,RAB18,GNA12,UPF1,ATP6V1D,KIF18A,ATAD2,ATP5MC3,DDX5,ASNA1,ATP6V1C1,HRAS,DDX52 |
| 3.280e-11 | -24.14 | GSE3982_EOSINOPHIL_VS_TH1_DN | MSigDB lists | GSE3982_EOSINOPHIL_VS_TH1_DN | 185 | 64 | 17377 | 2626 |
FOXM1,MRPL39,SUZ12,PTTG1,TMEM109,OLA1,C5orf30,ZFYVE21,SMARCA4,PARN,REEP5,METTL3,SPAG5,DDRGK1,RAD23A,IRF4,SNRNP25,RPN1,PA2G4,SLC31A1,ATP2A2,ZNHIT6,GRSF1,MRPL34,MDFIC,KNTC1,RNASEH2A,MINPP1,DNMT1,MTX2,UBE2M,TRIM14,NUDC,PRPF19,LDHB,METTL1,CCT2,SLC26A6,SEPT8,RANGAP1,MTX1,TOMM40,FXR1,CBFB,ASF1B,DHX57,PRDX1,BTBD1,CAND1,DNAJC10,DAP3,BIRC5,LSM6,NEIL3,GOLGA8A,LRPPRC,FN3KRP,UQCRH,MDH1,COPS6,IDH3B,LTA4H,TUBB,IFI16 |
| 3.378e-11 | -24.11 | SNRPE (small nuclear ribonucleoprotein polypeptide E) | protein interactions | 6635 | 143 | 56 | 17029 | 2761 |
UNK,SART1,MAPRE1,CDC40,EWSR1,CHERP,XAB2,SF3B1,OLA1,CUL1,TOP2B,SNRPD3,PDCD7,GGPS1,SF3B2,CAPN2,SNUPN,CMTR2,EFTUD2,GEMIN6,GPATCH1,GEMIN4,AQR,STRAP,LUC7L2,CDC5L,CDC37,SNRNP200,RBM42,SNRPB,PPIE,SF3B6,CRNKL1,CUL3,DDX20,PRPF3,SF3A2,SNRPA,CLNS1A,DDX23,CAND1,GEMIN5,PCM1,HSPA4,LSM6,U2SURP,PRPF4,YWHAZ,SNRPG,SNRNP70,ZNF830,CDK2,YWHAH,HRAS,GEMIN7,DDX42 |
| 3.468e-11 | -24.08 | GSE20727_CTRL_VS_ROS_INH_AND_DNFB_ALLERGEN_TREATED_DC_DN | MSigDB lists | GSE20727_CTRL_VS_ROS_INH_AND_DNFB_ALLERGEN_TREATED_DC_DN | 181 | 63 | 17377 | 2626 |
MAGEH1,LIME1,TXN,GOLPH3L,HJURP,MRPS15,SEC61G,HEXB,TAP1,C5orf30,KIF23,SDF2L1,PLXNA1,UBE4A,TMED3,NDUFS7,TMEM179B,GNS,SUB1,CCNA2,IARS,NDUFB4,SEC24C,PRC1,ATG13,AHCY,TECR,GINS1,BAK1,PLK1,SRP72,MND1,USO1,DPM1,AACS,RDH10,MKI67,MYBL2,LRRC8A,MRPL16,TMEM147,MCFD2,ANLN,ICMT,KRTCAP2,ECH1,ARF4,PSMC4,STOML2,TMEM41A,GOLGA2,PSMD3,FTSJ1,SIL1,HMGB2,KPNA2,SSNA1,PLOD3,E2F2,SSSCA1,AAAS,B4GALT2,TMEM33 |
| 3.468e-11 | -24.08 | GSE37533_PPARG2_FOXP3_VS_FOXP3_TRANSDUCED_CD4_TCELL_UP | MSigDB lists | GSE37533_PPARG2_FOXP3_VS_FOXP3_TRANSDUCED_CD4_TCELL_UP | 181 | 63 | 17377 | 2626 |
RMND5A,PRPF38B,MDH2,UROD,MCCC1,CERK,NANS,DNAJB1,SNN,RGS2,MAPK14,LYN,PDXDC1,POLR3K,GIT2,WRB,HMG20A,PABPC4,WRNIP1,SLC25A36,ATG4A,MOAP1,FARSA,ASAP2,NDUFA2,LRRC8D,DNAAF2,SEC24C,BDH1,TTC3,CNN2,METTL9,MOSPD1,LDHB,AMPD2,TDP1,DDX28,PHF10,ZFP64,FAM172A,CUL3,SEPT8,ARHGDIB,UBE4B,USP22,BICD2,RIT1,CCNF,ZFAND5,BSDC1,RBM38,CLNS1A,GLOD4,RAD51C,CAPN7,TFDP1,PITPNA,GALNT10,WIPI2,RRS1,WDR91,ZMAT3,POLQ |
| 3.468e-11 | -24.08 | GSE7764_IL15_TREATED_VS_CTRL_NK_CELL_24H_UP | MSigDB lists | GSE7764_IL15_TREATED_VS_CTRL_NK_CELL_24H_UP | 181 | 63 | 17377 | 2626 |
COMMD10,TP53RK,NOP2,NQO1,CLSPN,TM9SF4,CENPF,TMEM97,SLC29A1,NCAPG,BZW2,MIS12,MBD4,USP5,MOAP1,KIFC1,CDKN2C,ANKLE1,SLC31A1,CCNA2,IARS,METTL14,CENPJ,ATIC,CTR9,TARDBP,GEMIN4,SLC25A1,TMEM39A,CDC123,LAP3,ABCF2,MYBL2,E2F3,PCGF6,DDX20,CKAP2L,CDCA2,NUSAP1,UHRF1BP1,CDC6,BRCA1,GSTCD,PATL1,TMEM201,ASF1B,MASTL,ALG3,KPNA1,MID1IP1,MTHFD2,PLAA,ATAD2,SYNCRIP,UAP1,BIRC5,WDR4,XRCC3,SCARB1,TMEM101,NANP,PPP5C,UBE2C |
| 3.699e-11 | -24.02 | cell cycle checkpoint | biological process | GO:0000075 | 193 | 66 | 17256 | 2622 |
ZNF207,BCL2L1,CCNB1,MAPK14,FANCI,PCNA,BABAM2,MDM2,NABP1,CDKN1B,CEP63,ATF2,CARM1,PRPF19,CDC5L,PLK1,PLK3,BTG2,NSUN2,TAOK1,MRNIP,CDC6,BRCA1,AURKB,SOX4,DOT1L,RPS27A,E2F4,H2AFX,CHEK2,VPS4A,TFDP2,CLSPN,BABAM1,CENPF,CDT1,TOP2B,EIF2AK4,SPDL1,BLM,CNOT11,CNOT3,MAD2L2,RPA2,DTL,RFWD3,RB1,INTS7,CENPJ,NABP2,MSH2,PTPN11,TIMELESS,GTSE1,KNTC1,CNOT6L,TGFB1,PRKDC,CNOT9,TFDP1,PML,E2F1,CNOT6,ZNF830,CDK2,HRAS |
| 3.729e-11 | -24.01 | PAN2 (poly(A) specific ribonuclease subunit PAN2) | protein interactions | 9924 | 361 | 108 | 17029 | 2761 |
SART1,TXN,H2AFZ,HNRNPAB,RPLP2,IVNS1ABP,MRPL39,DYNLL1,MYH9,SNRPD3,BRIX1,ATP6V1B2,SEC16A,STMN1,PCBP1,LYN,GNB2,PABPC4,RPL11,RPL23A,PRNP,HNRNPA2B1,FARSA,HADHB,CLTB,CFL1,TIMM50,CCT2,RPL29,RPL35,ERF,SNRPB,RPL38,DNAJA1,ERC1,EIF3G,RPS9,EIF3H,CLNS1A,ASF1B,SRSF1,CHCHD3,RPL37,EIF4ENIF1,RPS27A,RPS14,NSMCE2,CORO1C,MYO18A,ACTB,RPS26,MYL12B,TUBB,RPS2,PPP1R12A,SRSF6,DHX9,RPL15,PAWR,THRAP3,QSOX2,MYL6B,RPA2,CD59,MEX3C,CBWD2,RPL17,EFTUD2,CAPZA1,YBX1,RPL19,CNN2,FBL,GNAI2,PABPC1,MYO5A,HNRNPM,SPTAN1,TRAFD1,PRKDC,SF3B6,RPS10,RPL6,TUFM,RPL8,RPS24,BCLAF1,CAPZA2,PLEC,PKM,RPL27A,KIF11,CCT8,MATR3,SF3A2,RPA1,RPL36,PCM1,RPL32,RBMX,GLG1,RUVBL2,ATP5F1A,TCOF1,SRSF3,SNRNP70,RBBP4,TOB1 |
| 4.015e-11 | -23.94 | GSE28726_NAIVE_VS_ACTIVATED_VA24NEG_NKTCELL_UP | MSigDB lists | GSE28726_NAIVE_VS_ACTIVATED_VA24NEG_NKTCELL_UP | 190 | 65 | 17377 | 2626 |
SRM,EXOC3,TXN,DYNLL1,CUL1,SLC29A1,ZNF267,SNAPC4,BCAT2,PSMD1,SNUPN,PSMA6,UTP18,TXLNA,SRI,TRA2B,RPN2,AHCYL1,ANKLE2,POU2AF1,COPS8,SEC61B,HNRNPF,PSMG1,NUTF2,UTP3,MCM2,SLC25A5,EIF3G,ALG3,PPP2CA,DHX16,HPS5,TBL3,NCLN,KPNA2,SNRPG,RRS1,MIF,NCOR2,ADO,PNO1,HDDC2,TFAP4,RPA2,ATP6V0A2,SS18L1,YBX1,GEMIN4,LPCAT1,MLEC,TSTA3,ADSL,TOMM40,PRDX1,EPRS,HSPBP1,CCDC86,SYNCRIP,LRPPRC,SLC16A1,RUVBL2,HRAS,DDB1,ZBTB24 |
| 4.162e-11 | -23.90 | GSE40274_IRF4_VS_FOXP3_AND_IRF4_TRANSDUCED_ACTIVATED_CD4_TCELL_UP | MSigDB lists | GSE40274_IRF4_VS_FOXP3_AND_IRF4_TRANSDUCED_ACTIVATED_CD4_TCELL_UP | 165 | 59 | 17377 | 2626 |
CYTIP,CMAS,UNK,LZTR1,TMEM41B,MYH9,DHX8,JMJD6,SND1,NCKAP1,TWF2,MAP1LC3B,ETS1,SYNRG,PAPOLA,VASP,GART,INPP5A,ANXA5,JOSD1,STRAP,TMED2,DCTN1,ELOVL5,TRAPPC9,RHOA,TRAFD1,NCK1,VHL,NSDHL,MTA2,ANAPC2,AZI2,KDM1B,BSDC1,EIF3H,CLNS1A,MYO1F,UBTF,PLD3,NUCB1,HGS,KPNA4,MID1IP1,VPS26B,SNAP29,FAM3C,DCAF11,CABIN1,FKBP5,ACTB,SPRYD4,CHMP7,MAPK1,TAF6,IGBP1,CBX4,GPATCH4,ZC3HC1 |
| 4.211e-11 | -23.89 | regulation of cellular biosynthetic process | biological process | GO:0031326 | 4464 | 815 | 17256 | 2622 |
ZBTB10,KDM4A,HEXB,XIAP,CCNL2,EDRF1,RBM4,ZNF275,CDK5,CALM2,USF1,PSMD1,CIPC,THAP4,DNM2,CRY2,NUP153,FNIP2,ECD,SENP1,PLK3,ZNF672,ZNF559,AATF,GABPA,EHMT1,WDHD1,MIER2,TOPORS,ARF4,STOML2,BRMS1,BOLA3,MID1IP1,SMAD2,RPS27A,ZNF689,AXIN1,PRDX5,OGT,VIPAS39,RNASEL,TRIM52,TFDP2,SMAD1,E2F2,ZNF75A,AAAS,PDCD4,ZNF720,SSRP1,HIVEP3,DHX9,EZH1,EIF2AK4,PSMD9,PARN,CDC73,MCTS1,DDRGK1,TFAP4,SMC3,MEGF8,PHF14,ZNF326,FOXN2,MYDGF,PABPC1,NUP85,NSUN4,CYFIP1,IFRD1,ETV3,FOXK1,RB1CC1,ZMYND11,MTA2,GTPBP4,MYBL2,ITM2A,BCLAF1,CBFA2T2,ELK1,EIF4H,PDLIM1,ETS2,SETD3,CNOT6,ZNF830,SGF29,RNF139,NUP58,EGLN1,ZNF207,RHOG,ZNF296,KARS,SARNP,TRERF1,IVNS1ABP,UBR2,PTTG1,WDTC1,CREBL2,ZNF267,INO80E,SAFB2,RCOR3,TCF19,APP,AHCTF1,ZNF420,SP100,ZKSCAN1,MTA1,GMEB1,NUP107,ZNF226,MAVS,ATF2,RBM15,ZC3H3,RPRD1B,CGGBP1,CPNE1,PSRC1,POLR2L,EID1,KAT7,WBP2,RPL38,POLR2D,CIRBP,E2F3,HTATIP2,PFKFB3,MEF2D,TAZ,DDX17,TAF2,PPP2CA,CHCHD3,HIPK2,TICAM1,FUS,ZBTB11,LRP8,USP13,COMMD10,ZNF786,ZNF445,ZFP91,HABP4,TRAK1,JMJD6,GMCL1,ABHD14B,WDR5,ETS1,NEXMIF,ZNF92,PPP1R3B,ZBTB45,PSMD2,SUV39H2,PPP1R8,PRDM4,ZNF260,LTN1,ZNF710,GTF2H2,MED22,PDPK1,PPP3CA,TNFAIP3,ZNF512,ZP3,PICALM,ZNF862,ZNF180,KEAP1,GPS2,PITX1,LRPPRC,PML,HMGB2,CD81,PARP10,IGBP1,USF2,YWHAH,THAP5,FAF1,AGRN,THOC1,AAMDC,GPBP1L1,TRIM11,PPP1R15B,FAM129A,RBM8A,CSNK2A1,SND1,BIRC2,CREM,PRNP,LIN9,TET3,PCNA,NUP210,GLIS2,ZNF639,ETV6,PIK3R2,NOC2L,EIF5,MYBL1,MTPN,CCAR1,RYBP,PTPRK,PLK1,SP3,CELSR2,RBX1,PBXIP1,BAZ2A,ZBED5,MRPL12,EZR,CDC6,UBE2V1,LRP5,PBRM1,EAF2,BRCA1,USP21,TONSL,CHD3,ZNF367,E2F4,DVL1,ZNF45,BEND6,FAM208A,POT1,ZNF564,FUBP1,LZTR1,PHB2,CENPF,CTCF,CHCHD2,CDK13,DNAJB1,PPP3CB,RLF,ASXL2,CNOT11,CRLF3,ARID1B,LRRC14,SUB1,RB1,MLX,MED8,TIGAR,MBD2,SSBP3,ZNF746,CTR9,TIMELESS,MDFIC,AFF1,RBM3,ICE2,GLE1,MAML1,PREB,TRAPPC9,ACSL3,LDB1,UTP15,KRAS,EIF2AK1,RTF1,ZNF761,NFATC2IP,EIF4G2,IRF5,ZNF174,PSMC4,RXRB,SYNCRIP,ORMDL2,NLRC5,TBPL1,PRMT7,RUVBL2,USP7,CYLD,TRAF7,ARID2,FOXM1,DYNLL1,ZNF416,DUSP22,PCBP1,COMMD8,ZNF121,VAV1,CSDE1,ZBTB21,NRF1,PDK2,PSMA6,ZNF473,MDM2,KMT5C,ZNF302,PIN1,TARDBP,STRAP,SAP30L,ZNF583,DVL2,KDM3B,TIMP2,POLR2G,ZNF780B,PSMA8,BTG2,PPIE,NUP155,NFATC2,KDM1B,EIF3H,ATP1A1,SCAP,ZNF700,RBL1,MAFK,PSMD3,ZNF436,UHRF2,DNAJC17,NCOA1,H3F3A,SMAD4,ZNF146,BCL2L12,SLC30A9,CTDP1,UNK,MIF4GD,MTERF1,DAP,CDT1,AGO2,ARID5A,GTF3A,HMGN3,NKRF,CDK11B,PAGR1,FZD6,WRNIP1,PTPN2,IRF4,SS18L1,PTGES3,RBM15B,RPRD1A,RHOA,HMGN5,BTAF1,PRKDC,ZNF202,ZMYM5,PCGF1,TRIM26,BIRC5,TWSG1,L3MBTL3,TFE3,CDCA7L,BBX,E2F1,PKD2,RBPJ,TAF12,NR2F2,PGAM1,HIPK3,IFI16,TXN,NUP188,ZNF496,MAX,H2AFZ,TSC22D3,CXXC1,YTHDF3,UBE2I,EIF1B,COMMD6,MYEF2,PARK7,GLMP,PA2G4,NOL11,FIZ1,ZNF200,TAF5L,MAST2,SMARCE1,DNMT1,ZNF800,SEH1L,CDC5L,SRSF10,ZNF524,KLF10,AKT2,ELOA,DDX20,SUPT20H,AURKB,USP22,RFC2,CBFB,ZMYM3,IWS1,DOT1L,MAP3K4,HHEX,MKNK1,BRD2,PSMD8,RPS14,BTF3,ARRB2,TRAF5,ZNF598,CCDC59,NMD3,HDAC2,PTOV1,SVIP,DDX58,HSPH1,EWSR1,POLR2K,CHTF18,PRKAA1,NOTCH2,PMF1,SUPT7L,ZNF79,PSEN1,ZNF518A,METTL3,VPS25,YY1AP1,CNOT3,JMY,CFLAR,LHX8,MEX3C,KLF16,HDAC7,DAPK1,GNAI2,TNRC18,LPCAT1,EEF1D,TERF2,EIF5A,PHF10,ZNF84,ELL2,ZNF574,USF3,EXOSC9,ARID1A,ADRB2,C9orf40,CYFIP2,FXR1,KDM3A,MAP2K2,CCT8,PSMB3,PHF6,XRCC5,CAT,PFDN5,EPRS,ZNF777,SERTAD2,GOLGA2,EPOP,ZFP92,RBMX,QARS,MED15,CEBPG,PPP3R1,PIAS2,SAMD8,TCOF1,YY1,MAP3K5,RNF14,CDK2,CDKN2A,ZNF511,NDC1,DNMT3A,ATXN3,RWDD1,ZBTB37,RPS6KA1,RAF1,SUZ12,EIF3D,RAC1,MAGED1,PAIP2,TERF2IP,SPINDOC,CCNA2,ZNF75D,SHC1,KDM2A,UCHL5,LPIN2,MRPS27,CDKN1B,CDK12,SAP30,CCT2,BRD4,RFC3,ERF,CDC123,DRAP1,CUL3,ELP4,EDF1,H2AFV,PSMB9,ERC1,TRIM28,SERP1,CENPU,PRDM11,SUPT16H,EIF3K,VEZF1,ZNF282,HINT1,CERS6,SAFB,STAT1,H2AFX,ATF6,TRIM32,BEND3,EYA2,ATMIN,RHEBL1,POU3F2,NCOR2,DEPDC1,MECP2,TCF3,ARGLU1,SECISBP2,MYNN,BLM,POFUT1,FOXO3,HMG20A,MAD2L2,WWP2,GTF2F1,CCNK,PTEN,ELP5,CARF,CITED2,CREB1,CNOT6L,NCOA2,TSHZ1,ZFP64,KAT2A,NEK7,WDR18,ILF3,PARP4,RFXANK,KLF6,COMMD4,FADD,POLR2A,CBX3,PRDX3,ZHX1,TFDP1,KHSRP,DDX5,BRWD3,TAF6,CPEB2,PURA,FAM83G,RORB,ZBED3,CCNC,ZNF76,IER2,NOP2,HNRNPAB,UBN1,NF1,KMT2E,DNAJC24,PTP4A3,ZNF107,SIRT2,TAF6L,COMMD5,MAPK14,SNAPC4,ZNF696,EIF4A3,JAZF1,METTL14,PHTF1,SRI,ZBTB22,TCEA1,OGG1,ARID4A,CARM1,TRIM14,ELOF1,DEAF1,TRIM8,NCK1,VHL,RIOX2,RRM2,SOX4,KMT2C,ASF1B,GEMIN5,UBTF,PAF1,EIF4ENIF1,BRWD1,PQBP1,BAZ1B,ZNF268,CHEK2,CLU,PSMC1,UBE2D3,PPP1R12A,ZNF768,NACA,CIB1,MED13L,TIA1,MEF2A,THRAP3,RGS2,TTF1,SRRT,NUP205,LYAR,NFATC3,ZNF449,MED10,BUD31,ZNF335,BCL2,YBX1,ACAD8,MCPH1,ZNF189,HP1BP3,VOPP1,CREG1,ERLIN1,CIC,RPL6,GBA,PSMA1,EIF2A,SLTM,DAPK3,CAND1,TSC1,NFIL3,SIAH2,NUP62,ZFP90,RBBP4,HNRNPDL,TOB1,N4BP2L2,ZBTB24,SMARCD1,ADNP2,TCF12,MBD1,ASH1L,MPHOSPH8,SMARCA4,PLAGL2,NSD3,IRF3,ORC1,CHD1,MEAF6,MXD1,PAIP1,HNRNPA2B1,SAP130,RRN3,NVL,AKAP8,CHTOP,F2R,UTP4,ZNF770,RLIM,MOSPD1,CHP1,POU2AF1,FAM172A,ZNF500,RNF25,PCGF6,PSMB7,ATXN1,BOLA1,GLO1,ERBIN,MBD3,RPS9,PDHX,ZNF317,TAB2,HNRNPR,TULP3,STAT6,ARNTL,SCARB1,AKNA,SMURF1,MAPK1,BRD9,CBX4,NAT14,DNAJC2,ZNF316,RAE1,EYA1,SCYL1,NUP54,DBF4,KLF13,PAWR,MXD4,FBXO5,FASTKD3,KMT5A,PELO,NABP2,H2AFY,ANP32A,BRD7,ARHGEF2,STAT3,TGFB1,SAMD4B,ELOVL5,PHF20L1,COA3,DCAF6,HMGN1,PSPC1,MIER1,RCOR1,PRMT2,MEN1,ZNF407,CDK11A,MAPK3,TFEB,HSPA1B,CNOT9,LEMD2,UPF1,ATAD2,KMT2B,ZRANB2,CENPT,ZMIZ1,HRAS,TERF1 |
| 4.233e-11 | -23.89 | mRNA transport | biological process | GO:0051028 | 144 | 54 | 17256 | 2622 |
NDC1,NUP188,CDC40,SARNP,THOC1,SRSF6,RAE1,RBM8A,DHX9,ALKBH5,NUP54,AGFG1,XPO7,NUP205,HNRNPA2B1,AHCTF1,NUP210,EIF4A3,SRSF4,NUP107,UPF2,NUP153,GLE1,CHTOP,CPSF4,MVP,ZC3H3,NUP85,SEH1L,SRSF11,EIF5A,FYTTD1,NXT1,POLR2D,RNPS1,SLBP,NUP155,BICD2,NUTF2,SRSF5,DDX39A,SYMPK,NPIPA1,SRSF1,IWS1,HHEX,UPF1,LRPPRC,KHSRP,NUP62,SRSF3,NUP58,AAAS,NXT2 |
| 4.273e-11 | -23.88 | GSE36476_CTRL_VS_TSST_ACT_72H_MEMORY_CD4_TCELL_YOUNG_DN | MSigDB lists | GSE36476_CTRL_VS_TSST_ACT_72H_MEMORY_CD4_TCELL_YOUNG_DN | 186 | 64 | 17377 | 2626 |
TMEM106C,SRM,POLA2,KIF3B,IMMT,TXN,MCM10,NQO1,FOXM1,PTTG1,CDCA3,CDCA8,PXMP2,KIF2C,CCNB1,NCAPG,STMN1,MRPL19,MYL6B,FANCI,SPAG5,SAC3D1,FBXO5,KIFC1,DTL,OIP5,FANCL,RB1,PCNA,MCM5,DUT,BDH1,PPCDC,CENPM,TALDO1,SAP30,TK1,MLEC,ASPM,RAD51AP1,PBK,KIF15,MKI67,RRM2,NUSAP1,CDC6,MCM2,SHCBP1,SLC25A5,KIF11,TARS,SRSF1,DSN1,STT3A,BIRC5,NEIL3,CORO1C,CEP55,PGAM1,CCNB2,UBE2C,ESPL1,RAD51D,POLQ |
| 4.363e-11 | -23.86 | POLR2A (RNA polymerase II subunit A) | protein interactions | 5430 | 300 | 94 | 17029 | 2761 |
DNMT3A,NF1,UBN1,IVNS1ABP,XAB2,CSNK2A1,SMARCA4,IRF3,SND1,CCNL2,ATP6V1B2,PCNA,PSMA6,PIN1,INTS1,NABP1,TCEA1,ASB6,RPRD1B,CDK12,CTDSP2,EBAG9,CSTF1,PRPF19,ERCC1,POLR2G,POLR2L,VHL,ELOA,HNRNPF,POLR2D,WDHD1,WDR82,BRCA1,MCM2,PSMB9,IWS1,PAF1,TRAM2,HNRNPR,SAFB,MAP4,PQBP1,H2AFX,ACTB,FUS,SMURF1,SSRP1,CTDP1,UNK,EWSR1,POLR2K,DCTN2,TRAK1,DHX9,CTCF,CDC73,SRRT,WWP2,GTF2F1,CCNK,SUB1,SMC3,MED10,PPIG,MBD2,XPA,PPP4R1,ZNF326,CTR9,AFF1,UBE3B,CREB1,RPAP3,HMGN1,POLR2I,MTA2,ILF3,MEN1,POLR2A,RPA1,XRCC5,CBX3,CAND1,UPF1,POLR2J,NSMF,CABIN1,DDX5,RUVBL2,CDK2,DDB1,IFI16,EGLN1 |
| 4.369e-11 | -23.85 | Asparagine N-linked glycosylation | REACTOME pathways | R-HSA-446203 | 284 | 91 | 10287 | 1696 |
TMED7,GNPNAT1,COPA,PRKCSH,DYNLL1,COPE,ANK3,MOGS,NANS,SEC16A,RNF103,ANKRD28,NAPG,RAD23B,PPP6C,RPN2,TFG,LMAN1,MGAT5,DCTN1,USO1,TMEM115,DPM1,SLC17A5,AMDHD2,MCFD2,EDEM2,RAB1A,ARF4,MAN2A2,ALG3,DDOST,STT3A,TMED10,RPS27A,SEL1L,MIA2,ST3GAL2,B4GALT3,NGLY1,PSMC1,CSNK1D,B4GALT2,DYNC1LI2,CMAS,GORASP1,B4GALT5,UBXN1,DCTN2,GNE,B4GALT1,ARF1,TMED3,B4GALT4,COPG2,COPB2,MAN1A1,CD59,RPN1,NUS1,DAD1,ARF5,SEC24C,FUT8,ST8SIA2,PPP6R1,SLC35A1,TMED2,RNF5,KDELR1,SPTAN1,PREB,TRAPPC9,MLEC,TSTA3,MAN1B1,COG1,SYVN1,GOSR1,NEU1,SEC31A,DERL1,SEC23IP,GOLGA2,MAGT1,UAP1,NSF,CTSA,NANP,PPP6R3,RNF139 |
| 4.531e-11 | -23.82 | PENG_LEUCINE_DEPRIVATION_DN | MSigDB lists | PENG_LEUCINE_DEPRIVATION_DN | 182 | 63 | 17377 | 2626 |
SRM,PPIB,DYNLL1,CDK2AP2,TMEM109,DHX9,CYCS,SLC29A1,BCL2L1,FKBP2,CCNB1,GGA2,TFRC,FANCI,COPB2,EBP,PAPOLA,FARSA,ERH,PSMD2,GART,PSMD1,CCNA2,AHSA1,EI24,FAM89B,PTGES3,EIF5,PDIA6,LPCAT1,ZC3H3,LDHB,TGFB1,CCT2,MLEC,TK1,SEC61B,WDR1,AMD1,PSMB7,ILF3,MRPL12,LDHA,EMP3,GLO1,NUTF2,DNAJA1,TOMM40,VDAC1,OGFR,EIF4G2,API5,XRCC5,HSPA4,BRD2,POLR2J,PSMD3,TIMM17A,KPNA2,YWHAH,PGAM1,MRPL3,BYSL |
| 4.593e-11 | -23.80 | SNRNP200 (small nuclear ribonucleoprotein U5 subunit 200) | protein interactions | 23020 | 179 | 65 | 17029 | 2761 |
SART1,PRKAB1,ZBTB10,FOXM1,GPBP1L1,XAB2,SUZ12,SF3B1,USP39,SNRPD3,UBE2I,SF3B2,EIF4A3,PIN1,CRY2,TARDBP,TCEA1,ECD,USP34,PRPF19,CDC5L,SNRNP200,SNRPB,CRNKL1,SMU1,RNPS1,CUL3,WDHD1,LSM8,PRPF3,BRCA1,MCM2,DHX15,SRSF1,HNRNPR,PRPF4,SNRPG,SMNDC1,TUBB,PRPF4B,C9orf78,TOP2B,BLM,PDCD7,FERMT3,TFAP4,RPA2,HUWE1,MCM5,EFTUD2,ZNF746,YBX1,PABPC1,LUC7L2,STAU1,ZMYND11,SF3A2,PHF6,ISG15,DDX23,CAND1,RPA1,C1orf131,RUVBL2,SNRNP70 |
| 4.639e-11 | -23.79 | pyrophosphatase activity | molecular function | GO:0016462 | 890 | 209 | 17224 | 2647 |
RAB14,DDX47,ABCC10,YTHDC2,TAP1,DHX8,ABCB10,KIF2C,ATP5PF,KIFC1,RAB8A,RAP1A,CDC42,EIF4A3,RAB35,XRCC2,RAB4A,ATP13A3,DNM2,KIF22,EIF5,ABCC5,SNRNP200,RHOBTB3,NRAS,SEPT9,KIF15,DDX20,ARHGDIB,PBRM1,MCM2,RFC2,RAB5B,LSG1,RAB22A,DHX15,RAB2B,GINS4,ARF4,RHEB,SEPT1,RAD18,KIF18B,CHD3,MYO18A,ATP6V0C,CLU,VPS4A,NUDT11,PSMC1,LONP2,ATP6V0E1,DDX42,DDX58,HSPH1,RECQL,MUT,RHOC,CHTF18,GSPT2,DHX9,RAB23,KLC1,KIF23,TOP2B,RAB6A,MYL6B,TMEM250,DDX56,SMC3,MCM5,KIF13B,EFTUD2,MSH2,ATP6V0A2,GNAI2,ATP6V0D1,PPA1,ABCC1,DDX28,NTPCR,NOA1,DHX29,NUDT4,GTPBP4,SEPT8,KRAS,RIT1,SEPT7,EIF4H,ABCF1,CCT8,RHOB,PSMC4,XRCC5,GNAS,NSF,ATP5F1A,RUVBL2,RBBP4,MYO9A,NUDT3,RHOG,ABCA3,RAB11B,DYNLL1,CHD1L,RAC1,PMS2,OLA1,MYH9,RRAGC,SMARCA4,EFL1,ATP6V1B2,GNB2,CHD1,RAB21,ATP6V0B,ATP2A2,RALB,PIN1,KIF14,DUT,SEPT11,TAP2,AQR,DNAL4,DCTN1,ATP6V1G1,ENPP4,RFC3,ATP13A1,RAB7A,ATP6V0A1,RAB1A,DHX57,RAD54B,DDX17,KIF2A,RAD51C,IDE,ATP1A1,HSPA4,RAB24,DHX16,PPA2,CANT1,XRCC3,ABCA1,DYNC1LI2,RAD51D,TUBB,RHEBL1,POLQ,KIF3B,SHPRH,TWNK,TOR3A,DCTN2,MYO9B,ARF1,ATP5F1B,BLM,IFT27,RAB11A,GFM2,WRNIP1,GTPBP3,KIF5B,STARD9,ARF5,ABCD1,DDX31,GTF2H2,MSH6,MYO5A,GINS1,RHOA,DDX24,HELB,BTAF1,ABCF2,ATP2C1,TUFM,BMS1,ATP5MF,RHOT1,DDX39A,GUF1,KIF11,MACF1,RHOT2,HSPA1B,MYO1F,DDX23,MFN2,RAB18,GNA12,UPF1,ATP6V1D,KIF18A,ATAD2,ATP5MC3,DDX5,ASNA1,ATP6V1C1,HRAS,DDX52 |
| 4.686e-11 | -23.78 | GO_NUCLEAR_EXPORT | MSigDB lists | GO_NUCLEAR_EXPORT | 141 | 53 | 17377 | 2626 |
RPS15,CDC40,SARNP,NUP188,THOC1,RAE1,SRSF6,RBM8A,ALKBH5,NUP54,AGFG1,XPO7,NUP205,HNRNPA2B1,NUP210,EIF4A3,SRSF4,NUP107,UPF2,NUP153,GLE1,AHCYL1,CHTOP,ZC3H3,NUP85,SEH1L,SRSF10,TGFB1,SRSF11,EIF5A,FYTTD1,NXT1,POLR2D,RNPS1,ATXN1,SLBP,NUP155,NUTF2,SRSF5,BUD13,DDX39A,LSG1,RPSA,SRSF1,HHEX,TSC1,UPF1,NUP62,SRSF3,RRS1,SMURF1,NMD3,AAAS |
| 4.817e-11 | -23.76 | regulation of nucleic acid-templated transcription | biological process | GO:1903506 | 3752 | 699 | 17256 | 2622 |
ZBTB10,KDM4A,HEXB,XIAP,CCNL2,EDRF1,ZNF275,CDK5,USF1,PSMD1,CIPC,THAP4,DNM2,CRY2,FNIP2,ECD,SENP1,PLK3,ZNF672,ZNF559,AATF,GABPA,EHMT1,WDHD1,MIER2,TOPORS,ARF4,BRMS1,BOLA3,SMAD2,RPS27A,ZNF689,AXIN1,PRDX5,OGT,VIPAS39,RNASEL,TRIM52,TFDP2,SMAD1,E2F2,ZNF75A,PDCD4,ZNF720,SSRP1,HIVEP3,DHX9,EZH1,EIF2AK4,PSMD9,CDC73,MCTS1,DDRGK1,TFAP4,MEGF8,PHF14,ZNF326,FOXN2,MYDGF,NUP85,IFRD1,ETV3,FOXK1,RB1CC1,ZMYND11,MTA2,MYBL2,BCLAF1,CBFA2T2,ELK1,PDLIM1,ETS2,SETD3,CNOT6,SGF29,EGLN1,ZNF207,RHOG,ZNF296,KARS,SARNP,TRERF1,IVNS1ABP,UBR2,PTTG1,WDTC1,CREBL2,ZNF267,INO80E,SAFB2,RCOR3,TCF19,APP,AHCTF1,ZNF420,SP100,ZKSCAN1,MTA1,GMEB1,NUP107,ZNF226,MAVS,ATF2,RBM15,ZC3H3,RPRD1B,CGGBP1,CPNE1,PSRC1,POLR2L,EID1,KAT7,WBP2,E2F3,HTATIP2,MEF2D,DDX17,TAF2,PPP2CA,CHCHD3,HIPK2,TICAM1,FUS,ZBTB11,LRP8,USP13,COMMD10,ZNF786,ZNF445,ZFP91,HABP4,TRAK1,JMJD6,GMCL1,ABHD14B,WDR5,ETS1,NEXMIF,ZNF92,ZBTB45,PSMD2,SUV39H2,PPP1R8,PRDM4,ZNF260,ZNF710,GTF2H2,MED22,PDPK1,PPP3CA,TNFAIP3,ZNF512,ZP3,PICALM,ZNF862,ZNF180,KEAP1,GPS2,PITX1,LRPPRC,PML,HMGB2,CD81,PARP10,IGBP1,USF2,YWHAH,THAP5,FAF1,AGRN,THOC1,AAMDC,GPBP1L1,TRIM11,CSNK2A1,SND1,BIRC2,CREM,PRNP,LIN9,TET3,PCNA,GLIS2,ZNF639,ETV6,PIK3R2,NOC2L,MYBL1,MTPN,CCAR1,RYBP,PTPRK,PLK1,SP3,CELSR2,RBX1,PBXIP1,BAZ2A,ZBED5,MRPL12,EZR,CDC6,UBE2V1,LRP5,PBRM1,EAF2,BRCA1,USP21,TONSL,CHD3,ZNF367,E2F4,DVL1,ZNF45,BEND6,FAM208A,ZNF564,FUBP1,LZTR1,PHB2,CENPF,CTCF,CHCHD2,CDK13,DNAJB1,PPP3CB,RLF,ASXL2,CNOT11,CRLF3,ARID1B,LRRC14,SUB1,RB1,MLX,MED8,MBD2,SSBP3,ZNF746,CTR9,TIMELESS,MDFIC,AFF1,ICE2,MAML1,PREB,TRAPPC9,LDB1,UTP15,KRAS,RTF1,ZNF761,NFATC2IP,IRF5,ZNF174,PSMC4,RXRB,NLRC5,TBPL1,PRMT7,RUVBL2,USP7,CYLD,TRAF7,ARID2,FOXM1,DYNLL1,ZNF416,DUSP22,PCBP1,COMMD8,ZNF121,VAV1,CSDE1,NRF1,ZBTB21,PSMA6,ZNF473,MDM2,KMT5C,ZNF302,PIN1,TARDBP,STRAP,SAP30L,ZNF583,DVL2,KDM3B,ZNF780B,PSMA8,BTG2,PPIE,NFATC2,KDM1B,SCAP,ZNF700,RBL1,MAFK,PSMD3,ZNF436,UHRF2,DNAJC17,NCOA1,H3F3A,SMAD4,ZNF146,BCL2L12,SLC30A9,CTDP1,MTERF1,DAP,CDT1,AGO2,ARID5A,GTF3A,HMGN3,NKRF,CDK11B,PAGR1,FZD6,PTPN2,IRF4,SS18L1,RBM15B,RPRD1A,RHOA,HMGN5,BTAF1,PRKDC,ZNF202,ZMYM5,PCGF1,TRIM26,BIRC5,TWSG1,L3MBTL3,TFE3,CDCA7L,BBX,E2F1,PKD2,RBPJ,TAF12,NR2F2,HIPK3,IFI16,TXN,ZNF496,H2AFZ,MAX,TSC22D3,CXXC1,UBE2I,COMMD6,PARK7,MYEF2,GLMP,PA2G4,NOL11,FIZ1,ZNF200,TAF5L,SMARCE1,DNMT1,ZNF800,CDC5L,SRSF10,ZNF524,KLF10,ELOA,DDX20,SUPT20H,AURKB,USP22,CBFB,ZMYM3,IWS1,DOT1L,HHEX,BRD2,PSMD8,RPS14,BTF3,ARRB2,TRAF5,CCDC59,HDAC2,PTOV1,DDX58,HSPH1,EWSR1,POLR2K,PRKAA1,NOTCH2,PMF1,SUPT7L,PSEN1,ZNF518A,ZNF79,VPS25,JMY,CNOT3,YY1AP1,CFLAR,LHX8,KLF16,HDAC7,TNRC18,EEF1D,TERF2,PHF10,ZNF84,ELL2,ZNF574,USF3,EXOSC9,ADRB2,ARID1A,C9orf40,KDM3A,MAP2K2,PSMB3,PHF6,XRCC5,CAT,PFDN5,ZNF777,SERTAD2,EPOP,ZFP92,RBMX,QARS,MED15,CEBPG,PPP3R1,PIAS2,YY1,MAP3K5,RNF14,CDK2,CDKN2A,ZNF511,DNMT3A,ATXN3,RWDD1,ZBTB37,RPS6KA1,RAF1,SUZ12,MAGED1,TERF2IP,SPINDOC,CCNA2,ZNF75D,SHC1,KDM2A,UCHL5,LPIN2,CDKN1B,CDK12,SAP30,BRD4,ERF,DRAP1,CUL3,ELP4,EDF1,H2AFV,PSMB9,TRIM28,ERC1,CENPU,PRDM11,SUPT16H,VEZF1,ZNF282,HINT1,CERS6,SAFB,STAT1,H2AFX,ATF6,TRIM32,BEND3,EYA2,ATMIN,RHEBL1,POU3F2,NCOR2,DEPDC1,MECP2,TCF3,MYNN,ARGLU1,BLM,POFUT1,FOXO3,HMG20A,MAD2L2,WWP2,GTF2F1,CCNK,PTEN,ELP5,CARF,CITED2,CREB1,CNOT6L,NCOA2,TSHZ1,ZFP64,KAT2A,ILF3,RFXANK,KLF6,COMMD4,FADD,POLR2A,CBX3,PRDX3,ZHX1,TFDP1,KHSRP,DDX5,BRWD3,TAF6,PURA,FAM83G,RORB,CCNC,ZBED3,ZNF76,IER2,NOP2,HNRNPAB,UBN1,KMT2E,PTP4A3,ZNF107,SIRT2,TAF6L,COMMD5,MAPK14,SNAPC4,ZNF696,JAZF1,PHTF1,SRI,ZBTB22,TCEA1,OGG1,ARID4A,CARM1,TRIM14,ELOF1,DEAF1,TRIM8,NCK1,VHL,RIOX2,RRM2,SOX4,KMT2C,ASF1B,UBTF,PAF1,BRWD1,PQBP1,BAZ1B,ZNF268,CHEK2,CLU,PSMC1,UBE2D3,PPP1R12A,ZNF768,NACA,CIB1,MED13L,MEF2A,THRAP3,SRRT,TTF1,LYAR,NFATC3,ZNF449,MED10,BUD31,ZNF335,YBX1,ACAD8,MCPH1,ZNF189,HP1BP3,VOPP1,CREG1,ERLIN1,CIC,RPL6,PSMA1,EIF2A,SLTM,DAPK3,CAND1,NFIL3,SIAH2,NUP62,ZFP90,RBBP4,HNRNPDL,TOB1,N4BP2L2,SMARCD1,ADNP2,ZBTB24,MBD1,TCF12,ASH1L,MPHOSPH8,SMARCA4,PLAGL2,NSD3,IRF3,ORC1,CHD1,MXD1,MEAF6,HNRNPA2B1,SAP130,RRN3,AKAP8,CHTOP,F2R,UTP4,ZNF770,RLIM,CHP1,MOSPD1,POU2AF1,FAM172A,ZNF500,RNF25,PSMB7,PCGF6,ATXN1,BOLA1,GLO1,ERBIN,MBD3,ZNF317,TAB2,STAT6,TULP3,ARNTL,AKNA,SMURF1,BRD9,MAPK1,CBX4,NAT14,DNAJC2,ZNF316,EYA1,SCYL1,KLF13,PAWR,MXD4,FBXO5,KMT5A,PELO,ANP32A,BRD7,ARHGEF2,H2AFY,STAT3,SAMD4B,TGFB1,PHF20L1,DCAF6,HMGN1,PSPC1,MIER1,RCOR1,PRMT2,MEN1,ZNF407,CDK11A,MAPK3,TFEB,HSPA1B,CNOT9,LEMD2,ATAD2,KMT2B,ZRANB2,CENPT,ZMIZ1,HRAS,TERF1 |
| 4.830e-11 | -23.75 | HNRNPM (heterogeneous nuclear ribonucleoprotein M) | protein interactions | 4670 | 249 | 82 | 17029 | 2761 |
ZNF207,CYLD,IVNS1ABP,UQCR10,SF3B1,TOR1AIP1,RBM8A,CUL1,PTP4A3,SND1,SNRPD3,UBE2I,SEC16A,MYEF2,RBM4,RPL11,SSR1,RPL23A,RAP1A,MDM2,EIF4A3,CRY2,TARDBP,LRRC59,CDC37,SRPK2,PRPF19,CDC5L,VHL,HNRNPF,RNPS1,CUL3,TOPORS,PRPF3,BRCA1,MCM2,MBD3,RPSA,SRSF1,DOT1L,SUPT16H,MRPL55,HNRNPR,RPS14,RRS1,ARRB2,RPS26,RPS2,DHX9,THRAP3,SRRT,LMNA,RPA2,GSTK1,SMC3,RRBP1,EFTUD2,ZNF746,RTCB,ZNF326,RPL19,STAT3,STAU1,PRRC2A,MTA2,RFXANK,RPL6,RPS24,SRSF5,MATR3,ABCF1,RPA1,CAND1,SYNCRIP,RBM25,RBMX,DDX5,SRSF3,CDK2,ECPAS,HNRNPDL,CD81 |
| 4.833e-11 | -23.75 | OSMAN_BLADDER_CANCER_DN | MSigDB lists | OSMAN_BLADDER_CANCER_DN | 344 | 99 | 17377 | 2626 |
CYTIP,SART1,ST13,SYS1,CKLF,TRAF7,RPLP2,TMEM41B,CDC42SE2,SNN,IKBIP,KCMF1,RBM4,ZNF275,C2orf68,RPL23A,CSDE1,ABL2,STRBP,SIAH1,RABGAP1L,SRSF4,CHTOP,AHCYL1,SENP1,CDK12,CTDSP2,ABCC5,PPIF,RPL29,RPL35,SNRNP200,HMGN4,CDC123,ZNF780B,AKT2,GNG7,RPL38,PRPF3,EDF1,DIDO1,BUD13,MRPS14,USP36,RPSA,RPL37,PPP2CA,SPATA2,SCAP,GRIPAP1,SAFB,OGT,QRSL1,FAU,H3F3A,TRAF5,PDCD4,DDX58,RPS15,SRSF6,RPL15,IP6K2,ARF1,PM20D2,GGA2,ASXL2,TTF1,RHBDD1,TMCC3,GART,MLX,ARHGEF2,RPL19,FBL,STAT3,HNRNPM,SAMD4B,ELOVL5,SCFD2,RPS10,RPS24,ARID1A,PRMT2,CBFA2T2,GOSR1,NMT2,CYB5A,RPL36,RPA1,GNAS,SERTAD2,PDCD6,SERF2,RPL32,PRDX3,DTX4,PML,WIPI2,ADNP2 |
| 4.839e-11 | -23.75 | GO_REGULATION_OF_AUTOPHAGY | MSigDB lists | GO_REGULATION_OF_AUTOPHAGY | 243 | 77 | 17377 | 2626 |
FEZ2,KDM4A,ZDHHC8,RRAGC,SIRT2,BCL2L1,UBQLN2,ATP6V1B2,BECN1,MAP1LC3B,PARK7,TRIM65,EPM2A,ABL2,CDK5,ATP6V0B,RALB,TBC1D14,PIK3R2,PARL,CISD2,HTRA2,DRAM2,ATP6V1G1,UBQLN4,TRIM8,RAB7A,ATP6V0A1,VDAC1,USP36,CHMP4A,TAB2,VPS26B,ATP6V0C,CHMP4B,STK11,CLN3,ATP6V0E1,CAPN1,SVIP,USP13,TBC1D12,SCOC,PHF23,DAP,PRKAA1,EIF2AK4,PIP4K2A,VMP1,DAPK1,ATP6V0A2,BCL2,PIKFYVE,LRSAM1,ATP6V0D1,TPCN1,RNF5,KAT2A,RB1CC1,GBA,PIP4K2C,USP10,ADRB2,SH3GLB1,DAPK3,MAPK3,TFEB,MTMR3,TSC1,ATP6V1D,GOLGA2,EXOC4,CTSA,PSAP,ATP6V1C1,SNRNP70,IFI16 |
| 4.871e-11 | -23.75 | tat (p14) | protein interactions | 155871 | 1717 | 376 | 17029 | 2761 |
H2AFZ,CXXC1,TAP1,CCNB1,MYEF2,POLR3K,PARK7,CALM2,CDK5,PSMD1,RAB4A,PDS5B,AP2B1,TRA2B,NUP153,TAF5L,DNMT1,PCBP2,SRSF10,CDC5L,BAK1,NRAS,KLF10,AATF,GABPA,AKT2,ELOA,HNRNPF,SMC2,SLC17A5,MCM2,RFC2,EIF3A,DOT1L,SMAD2,BRD2,TMED10,PSMD8,LIMK1,LUC7L3,AXIN1,ITGB1,COX5A,SMAD1,ARRB2,PFKP,HDAC2,SSRP1,COX5B,POLR2K,HLA-E,PRKAA1,DHX9,RRM1,TOP2B,CYCS,NOTCH2,PSMD9,ITGB5,MYL6B,LMNA,TFAP4,RPN1,EIF2S2,SMC3,ZNF326,CTPS1,PIKFYVE,NUP85,PABPC1,LUC7L2,EEF1D,SIGMAR1,ELL2,MTA2,GTPBP4,BCLAF1,ARID1A,PKM,FXR1,MAP2K2,MATR3,PSMB3,XRCC5,FAS,CAT,POLR2J,CSK,CEBPG,PPP3R1,GPI,YY1,CDK2,CDKN2A,DNMT3A,SARNP,NQO1,SUZ12,SF3B1,RAF1,ACTR3,ANK3,RAC1,MYH9,BCL2L1,EFL1,PRKACA,APP,PRKD3,AHCTF1,CCNA2,SHC1,MTA1,ADCY9,CDKN1B,ANAPC7,CFL1,GPX4,ADCY7,CCT2,RFC3,BRD4,POLR2L,KAT7,POLR2D,HTATIP2,EDF1,H2AFV,PSMB9,SERP1,SUPT16H,DDX17,TAF2,PPP2CA,KIF2A,HSPA4,PPP2R5A,HINT1,JAK1,GUCY1B1,TBL3,STAT1,H2AFX,ATF6,TRIM32,FUS,PDCD11,TUBB,ADAM23,RPS2,ZFP91,SRSF6,TCF3,FLOT1,ATP5F1B,WDR5,ETS1,FOXO3,POFUT1,HLA-A,GTF2F1,RBM17,FBXO3,PPP1R3B,CAPN2,PSMD2,PTEN,RPL17,PPP1R8,PTPN11,ANXA5,NAP1L4,MAP3K14,CREB1,TTLL12,SGCB,GTF2H2,NCOA2,HNRNPM,SMC4,NUDC,LDHB,PDPK1,PPP3CA,TNFAIP3,LONRF3,KAT2A,DDX24,GALC,NEK7,ZNF512,ILF3,LDHA,HEBP2,KIF11,PDE3B,POLR2A,RPA1,CBX3,KEAP1,POLE,HNRNPH3,PML,LY75,ASNA1,DDX5,TAF6,PURA,RORB,CCNC,THOC1,NOP2,RBM8A,SIRT2,KIF2C,SNRPD3,BRIX1,MAP1LC3B,MAPK14,PRNP,CREM,PAPOLA,PCNA,DPYSL2,ZNF639,IL6ST,PIK3R2,KIF22,TCEA1,OGG1,CDC37,SP3,METTL1,PLK1,SNRNP200,SEPT9,SNRPB,EZR,WDR82,CDC6,UBE2V1,BRCA1,PBRM1,PRKRA,SOX4,DHX15,UBTF,PAF1,NIP7,CHD3,E2F4,PPM1G,U2SURP,BAZ1B,ACTB,KPNA2,ROCK1,PSMC1,MYL12B,CAPN1,PPP1R12A,PHB2,SDC2,TIA1,MEF2A,COX4I1,CDK13,PPP3CB,DNAJB1,RGS2,NUP205,RB1,SUB1,NFATC3,MED8,MBD2,ORAI1,YBX1,AHCY,AFF1,MDFIC,BCL2,ABCC1,HP1BP3,POLR2I,GBA,UTP15,PSMA1,KRAS,EIF2A,ISG15,PSMC4,CAND1,SDHB,NAP1L1,YWHAZ,RUVBL2,ATP5F1A,RBBP4,CCNB2,SMARCD1,PRKAB1,ASH1L,IMMT,ARID2,DYNLL1,TOR1AIP1,SMARCA4,IRF3,PCBP1,MEAF6,HNRNPA2B1,MDM2,PSMA6,TARDBP,RPN2,AHCYL1,EBAG9,TIMP2,BIRC3,POLR2G,PGGT1B,PSMB7,NFATC2,MBD3,SRSF1,AFDN,DAP3,TAB2,STAT6,PSMD3,NCOA1,USP11,H3F3A,MAPK1,AP2S1,SMAD4,CBX4,MIF,CTDP1,PAWR,CDK11B,NCAPG,BZW2,TFRC,RGS1,WRNIP1,CTSS,PPIG,H2AFY,FBL,STAT3,CAMK2G,TGFB1,HMGN1,RHOA,NASP,BTAF1,PRKDC,PRKAR1B,TUFM,RCOR1,RANGAP1,MEN1,SNRPA,HSPA1B,MAPK3,HLA-B,CDCA7L,COX8A,E2F1,USP20,TAF12,SRSF3,HRAS,IFI16 |
| 5.131e-11 | -23.69 | SCHAEFFER_PROSTATE_DEVELOPMENT_6HR_DN | MSigDB lists | SCHAEFFER_PROSTATE_DEVELOPMENT_6HR_DN | 480 | 127 | 17377 | 2626 |
WASF2,SART1,IER2,PTMS,PPP1R37,DNMT3A,ST13,PRKCSH,UBR2,CXXC1,MAGED1,PLAGL2,BCL2L1,SND1,SNRPD3,HCFC1R1,UBE2I,CHD1,APP,RAD23A,SF3B2,CALM2,DPYSL2,TTC9C,TXLNA,NOC2L,CABLES2,ECD,DNMT1,FGFR1OP2,CFL1,SAP30,CLPTM1,KDM3B,TRIM8,TIMP2,BRD4,SEPT9,APH1A,NOL8,TLK1,TAOK1,LACTB,RRM2,SOX4,EML4,EIF3A,KIF2A,AHNAK,TBC1D17,PEX5,DDOST,CHD3,ITGB1,RWDD4,CHPT1,ZBTB11,CBX4,B4GALT2,PTOV1,BCL2L12,DNAJC2,GOLIM4,PKP4,KIAA0100,TCF3,CUTA,GADD45G,NDUFA4,SDF2L1,THRAP3,SPR,CSNK1A1,ITGB5,ETS1,METTL3,RFWD3,PSMD2,CLIC4,PTPN11,ARHGEF2,SLC38A10,CLDND1,CNN2,PTGES3,PIKFYVE,GNAI2,PHKG2,TMED2,ELOVL5,GCC2,ADAM17,NASP,PIGT,CSRP1,NEK7,DHX29,ILF3,RCOR1,KRAS,RANGAP1,MAP7D1,LLPH,BCLAF1,SEPT7,MACF1,SYMPK,BSDC1,RHOB,PHF6,PSMC4,CBX3,DERL1,CAT,HGS,SERTAD2,GOLGA4,ZHX1,L3MBTL3,TFDP1,YWHAZ,PSAP,SNRNP70,NR2F2,CDK2,NUDT3,ADNP2 |
| 5.200e-11 | -23.68 | GSE15930_NAIVE_VS_24H_IN_VITRO_STIM_IL12_CD8_TCELL_DN | MSigDB lists | GSE15930_NAIVE_VS_24H_IN_VITRO_STIM_IL12_CD8_TCELL_DN | 191 | 65 | 17377 | 2626 |
SRM,GALK1,GCLM,NOP2,CHERP,PDAP1,GADD45G,MOGS,OLA1,TMEM109,TMEM97,RRM1,KIF23,JMJD6,HAUS4,POMP,INO80E,FKBP2,SPR,IFT27,POLR3K,IRF4,RPN1,CLIC4,NVL,MCM5,SIVA1,PDS5B,PDCD2,RPF2,ALDH18A1,LRRC59,MTX2,PPA1,NUP85,HDHD2,CARM1,TACC3,ELOF1,METTL1,POLR2L,PRIM2,TSPAN31,RAD51AP1,MKI67,MRPS10,BRCA1,RHOT1,ANLN,MCM2,RFC2,TPD52L2,MRPL2,SLC19A1,CDKN2AIPNL,MTHFD2,BIRC5,DCK,CRCP,RBPJ,NDUFS5,PGAM1,HRAS,GCSH,DDX52 |
| 5.328e-11 | -23.66 | regulation of RNA biosynthetic process | biological process | GO:2001141 | 3760 | 700 | 17256 | 2622 |
ZBTB10,KDM4A,HEXB,XIAP,CCNL2,EDRF1,ZNF275,CDK5,USF1,PSMD1,CIPC,THAP4,DNM2,CRY2,FNIP2,ECD,SENP1,PLK3,ZNF672,ZNF559,AATF,GABPA,EHMT1,WDHD1,MIER2,TOPORS,ARF4,BRMS1,BOLA3,SMAD2,RPS27A,ZNF689,AXIN1,PRDX5,OGT,VIPAS39,RNASEL,TRIM52,TFDP2,SMAD1,E2F2,ZNF75A,PDCD4,ZNF720,SSRP1,HIVEP3,DHX9,EZH1,EIF2AK4,PSMD9,CDC73,MCTS1,DDRGK1,TFAP4,MEGF8,PHF14,ZNF326,FOXN2,MYDGF,NUP85,IFRD1,ETV3,FOXK1,RB1CC1,ZMYND11,MTA2,MYBL2,BCLAF1,CBFA2T2,ELK1,PDLIM1,ETS2,SETD3,CNOT6,SGF29,EGLN1,ZNF207,RHOG,ZNF296,KARS,SARNP,TRERF1,IVNS1ABP,UBR2,PTTG1,WDTC1,CREBL2,ZNF267,INO80E,SAFB2,RCOR3,TCF19,APP,AHCTF1,ZNF420,SP100,ZKSCAN1,MTA1,GMEB1,NUP107,ZNF226,MAVS,ATF2,RBM15,ZC3H3,RPRD1B,CGGBP1,CPNE1,PSRC1,POLR2L,EID1,KAT7,WBP2,E2F3,HTATIP2,MEF2D,DDX17,TAF2,PPP2CA,CHCHD3,HIPK2,TICAM1,FUS,ZBTB11,LRP8,USP13,COMMD10,ZNF786,ZNF445,ZFP91,HABP4,TRAK1,JMJD6,GMCL1,ABHD14B,WDR5,ETS1,NEXMIF,ZNF92,ZBTB45,PSMD2,SUV39H2,PPP1R8,PRDM4,ZNF260,ZNF710,GTF2H2,MED22,PDPK1,PPP3CA,TNFAIP3,ZNF512,ZP3,PICALM,ZNF862,ZNF180,KEAP1,GPS2,PITX1,LRPPRC,PML,HMGB2,CD81,PARP10,IGBP1,USF2,YWHAH,THAP5,FAF1,THOC1,AGRN,AAMDC,GPBP1L1,TRIM11,CSNK2A1,SND1,BIRC2,CREM,PRNP,LIN9,TET3,PCNA,GLIS2,ZNF639,ETV6,PIK3R2,NOC2L,MYBL1,MTPN,CCAR1,RYBP,PTPRK,PLK1,SP3,CELSR2,RBX1,PBXIP1,BAZ2A,ZBED5,MRPL12,EZR,CDC6,UBE2V1,LRP5,PBRM1,EAF2,BRCA1,USP21,TONSL,CHD3,ZNF367,E2F4,DVL1,ZNF45,BEND6,FAM208A,ZNF564,FUBP1,LZTR1,PHB2,CENPF,CTCF,CHCHD2,CDK13,DNAJB1,PPP3CB,RLF,ASXL2,CNOT11,CRLF3,ARID1B,LRRC14,SUB1,RB1,MLX,MED8,MBD2,SSBP3,ZNF746,CTR9,TIMELESS,MDFIC,AFF1,ICE2,MAML1,PREB,TRAPPC9,LDB1,UTP15,KRAS,RTF1,ZNF761,NFATC2IP,IRF5,ZNF174,PSMC4,RXRB,NLRC5,TBPL1,PRMT7,RUVBL2,USP7,CYLD,TRAF7,ARID2,FOXM1,DYNLL1,ZNF416,DUSP22,PCBP1,COMMD8,ZNF121,VAV1,CSDE1,NRF1,ZBTB21,PSMA6,ZNF473,MDM2,KMT5C,ZNF302,PIN1,TARDBP,STRAP,SAP30L,ZNF583,DVL2,KDM3B,ZNF780B,PSMA8,BTG2,PPIE,NFATC2,KDM1B,ZNF700,SCAP,RBL1,MAFK,PSMD3,ZNF436,UHRF2,DNAJC17,NCOA1,H3F3A,SMAD4,ZNF146,BCL2L12,SLC30A9,CTDP1,MTERF1,DAP,CDT1,AGO2,ARID5A,GTF3A,HMGN3,NKRF,CDK11B,PAGR1,FZD6,PTPN2,IRF4,SS18L1,RBM15B,RPRD1A,RHOA,HMGN5,BTAF1,PRKDC,ZNF202,ZMYM5,PCGF1,TRIM26,BIRC5,TWSG1,L3MBTL3,TFE3,CDCA7L,BBX,E2F1,PKD2,RBPJ,TAF12,NR2F2,HIPK3,IFI16,TXN,ZNF496,H2AFZ,MAX,TSC22D3,CXXC1,UBE2I,COMMD6,PARK7,MYEF2,GLMP,PA2G4,NOL11,FIZ1,ZNF200,TAF5L,SMARCE1,DNMT1,ZNF800,CDC5L,SRSF10,ZNF524,KLF10,ELOA,DDX20,SUPT20H,AURKB,USP22,CBFB,ZMYM3,IWS1,DOT1L,HHEX,BRD2,PSMD8,RPS14,BTF3,ARRB2,TRAF5,NMD3,CCDC59,HDAC2,PTOV1,DDX58,HSPH1,EWSR1,POLR2K,PRKAA1,NOTCH2,PMF1,SUPT7L,PSEN1,ZNF518A,ZNF79,VPS25,JMY,CNOT3,YY1AP1,CFLAR,LHX8,KLF16,HDAC7,TNRC18,EEF1D,TERF2,PHF10,ZNF84,ELL2,ZNF574,USF3,EXOSC9,ADRB2,ARID1A,C9orf40,KDM3A,MAP2K2,PSMB3,PHF6,XRCC5,CAT,PFDN5,ZNF777,SERTAD2,EPOP,ZFP92,RBMX,QARS,MED15,CEBPG,PPP3R1,PIAS2,YY1,MAP3K5,RNF14,CDK2,CDKN2A,ZNF511,DNMT3A,ATXN3,RWDD1,ZBTB37,RPS6KA1,RAF1,SUZ12,MAGED1,TERF2IP,SPINDOC,CCNA2,ZNF75D,SHC1,KDM2A,UCHL5,LPIN2,CDKN1B,CDK12,SAP30,BRD4,ERF,DRAP1,CUL3,ELP4,EDF1,H2AFV,PSMB9,TRIM28,ERC1,CENPU,PRDM11,SUPT16H,VEZF1,ZNF282,HINT1,CERS6,SAFB,STAT1,H2AFX,ATF6,TRIM32,BEND3,EYA2,ATMIN,RHEBL1,POU3F2,NCOR2,DEPDC1,MECP2,TCF3,MYNN,ARGLU1,BLM,POFUT1,FOXO3,HMG20A,MAD2L2,WWP2,GTF2F1,CCNK,PTEN,ELP5,CARF,CITED2,CREB1,CNOT6L,NCOA2,TSHZ1,ZFP64,KAT2A,ILF3,RFXANK,KLF6,COMMD4,FADD,POLR2A,CBX3,PRDX3,ZHX1,TFDP1,KHSRP,DDX5,BRWD3,TAF6,PURA,FAM83G,RORB,CCNC,ZBED3,ZNF76,IER2,NOP2,HNRNPAB,UBN1,KMT2E,PTP4A3,ZNF107,SIRT2,TAF6L,COMMD5,MAPK14,SNAPC4,ZNF696,JAZF1,PHTF1,SRI,ZBTB22,TCEA1,OGG1,ARID4A,CARM1,TRIM14,ELOF1,DEAF1,TRIM8,NCK1,VHL,RIOX2,RRM2,SOX4,KMT2C,ASF1B,UBTF,PAF1,BRWD1,PQBP1,BAZ1B,ZNF268,CHEK2,CLU,PSMC1,UBE2D3,PPP1R12A,ZNF768,NACA,CIB1,MED13L,MEF2A,THRAP3,SRRT,TTF1,LYAR,NFATC3,ZNF449,MED10,ZNF335,BUD31,YBX1,ACAD8,MCPH1,ZNF189,HP1BP3,VOPP1,CREG1,ERLIN1,CIC,RPL6,PSMA1,EIF2A,SLTM,DAPK3,CAND1,NFIL3,SIAH2,NUP62,ZFP90,RBBP4,HNRNPDL,TOB1,N4BP2L2,SMARCD1,ADNP2,ZBTB24,MBD1,TCF12,ASH1L,MPHOSPH8,SMARCA4,PLAGL2,NSD3,IRF3,ORC1,CHD1,MXD1,MEAF6,HNRNPA2B1,SAP130,RRN3,AKAP8,CHTOP,F2R,UTP4,ZNF770,RLIM,CHP1,MOSPD1,POU2AF1,FAM172A,ZNF500,RNF25,PSMB7,PCGF6,ATXN1,BOLA1,GLO1,ERBIN,MBD3,ZNF317,TAB2,STAT6,TULP3,ARNTL,AKNA,SMURF1,BRD9,MAPK1,CBX4,NAT14,DNAJC2,ZNF316,EYA1,SCYL1,KLF13,PAWR,MXD4,FBXO5,KMT5A,PELO,ANP32A,BRD7,ARHGEF2,H2AFY,STAT3,SAMD4B,TGFB1,PHF20L1,DCAF6,HMGN1,PSPC1,MIER1,RCOR1,PRMT2,MEN1,ZNF407,CDK11A,MAPK3,TFEB,HSPA1B,CNOT9,LEMD2,ATAD2,KMT2B,ZRANB2,CENPT,ZMIZ1,HRAS,TERF1 |
| 5.350e-11 | -23.65 | GO_RIBONUCLEOPROTEIN_COMPLEX_LOCALIZATION | MSigDB lists | GO_RIBONUCLEOPROTEIN_COMPLEX_LOCALIZATION | 114 | 46 | 17377 | 2626 |
RPS15,CDC40,SARNP,NUP188,THOC1,RAE1,SRSF6,RBM8A,ALKBH5,NUP54,AGFG1,NUP205,HNRNPA2B1,NUP210,EIF4A3,SRSF4,NUP107,UPF2,NUP153,GLE1,CHTOP,ZC3H3,NUP85,SEH1L,SRSF10,FYTTD1,SRSF11,EIF5A,NXT1,POLR2D,RNPS1,SLBP,NUP155,SRSF5,BUD13,DDX39A,RPSA,SRSF1,TSC1,HHEX,UPF1,NUP62,SRSF3,RRS1,NMD3,AAAS |
| 5.350e-11 | -23.65 | OUELLET_OVARIAN_CANCER_INVASIVE_VS_LMP_UP | MSigDB lists | OUELLET_OVARIAN_CANCER_INVASIVE_VS_LMP_UP | 114 | 46 | 17377 | 2626 |
NDUFV2,NDUFS1,MAPRE1,H2AFZ,POLR2K,RAF1,SUMO2,CYCS,HMGN3,SLC35B1,SNRPD3,OAT,NUP205,COPB2,SSR1,IARS,SRSF4,ATP13A3,YBX1,NUP153,TCEA1,HNRNPM,HMGN1,NASP,DPM1,PRKDC,LDHA,GLO1,DDX39A,SLC25A5,TARS,ARF4,RHEB,GNAS,SDHB,EPRS,TMED10,LRPPRC,YWHAZ,DDX5,HMGB2,MDH1,GPI,MRPL3,TUBB,ZNF146 |
| 5.390e-11 | -23.64 | ENO1 (enolase 1) | protein interactions | 2023 | 288 | 91 | 17029 | 2761 |
PDCD6IP,TXN,MPHOSPH8,IVNS1ABP,SUMO2,DHX8,CUL1,NIT2,FKBP2,ATP5PF,PARK7,BCAP31,PCNA,DUT,SRI,AKR1B1,TALDO1,ATF2,SMARCE1,CFL1,SZRD1,GPX4,PRPF19,CUL3,EZR,BRCA1,PITPNB,OGDH,MCM2,PEF1,DHX15,IWS1,HINT1,CHD3,VPS26B,LUC7L3,E2F4,MYO18A,H2AFX,FUS,CHEK2,PPP5C,SLC25A39,HDAC2,MIF,PPIB,TKT,KIF23,LETMD1,XPO7,RAPGEF6,CDC73,POFUT1,NUP205,NPLOC4,LMNA,EBP,WWP2,FBXO5,FKBP1A,SNRNP25,TNS3,NFATC3,HUWE1,MCM5,AHSA1,UPF2,TAGLN2,NAP1L4,FBL,MCPH1,HNRNPM,NUDC,LDHB,NIPSNAP1,STAU1,STRIP1,WDR1,LDHA,WDR81,ISG15,CAND1,CAT,RBM25,TXNDC16,HNRNPH3,YWHAZ,GPI,CDK2,PGAM1,IPO4 |
| 5.452e-11 | -23.63 | GO_CHROMOSOME_SEGREGATION | MSigDB lists | GO_CHROMOSOME_SEGREGATION | 248 | 78 | 17377 | 2626 |
ZNF207,CHMP2A,SKA3,PDCD6IP,ACTR3,PTTG1,NUF2,KIF2C,CCNB1,UBE2I,BECN1,MIS12,KIFC1,AHCTF1,NEK6,KIF14,AKAP8,NUP107,PDS5B,KIF22,TOP1MT,MCMBP,SEH1L,PLK1,PSRC1,TAOK1,CUL3,NUSAP1,CDCA2,AURKB,BRCA1,SMC2,CDC23,CHMP2B,SLC25A5,KIF2A,RAD51C,CHMP4A,DSN1,KIF18B,CEP55,CHMP4B,VPS4A,RRS1,NAA60,MAPRE1,HJURP,PHB2,CENPF,CDCA8,CTCF,KIF23,RACGAP1,TOP2B,PMF1,NCAPG,RAB11A,SPAG5,RB1,SMC3,NAA50,PRC1,KNTC1,CENPM,NUP85,SMC4,NUDC,RANGAP1,KIF11,KIF18A,BIRC5,CDCA5,FAM83D,CENPT,NDE1,CHMP7,ESPL1,TERF1 |
| 5.474e-11 | -23.63 | RAE1 (ribonucleic acid export 1) | protein interactions | 8480 | 122 | 50 | 17029 | 2761 |
POLA2,USP7,SART1,NUP188,TXN,DYNLL1,PTTG1,RBM8A,NUP54,CUL1,PABPC4,EEF2K,FKBP1A,PRKD3,SMC3,NUP107,CS,NUP153,TAGLN2,PABPC1,SEH1L,TACC3,CDC37,COPS8,AGGF1,DDX24,MIOS,PRIM2,KAT2A,SMU1,CUL3,ILF3,WDR82,ARMC8,SF3A2,PRIM1,PCM1,HINT1,DGCR8,WDR59,ATE1,KHSRP,NUP62,COPS6,USP11,SASS6,YWHAH,ZC3HAV1,IFI16,FAF1 |
| 5.667e-11 | -23.59 | MRPS9 (mitochondrial ribosomal protein S9) | protein interactions | 64965 | 104 | 45 | 17029 | 2761 |
EWSR1,MRPL42,MRPS2,MRPS15,MRPL39,MRPS26,LAMTOR3,SDHA,PARK7,NPLOC4,MRPL50,DDX56,STRBP,ZNF746,MRPS27,RBM3,MRPL40,MRPL21,ZC3H3,MRPL32,HNRNPM,NOL12,RBM42,MRPL12,CUL3,ILF3,ZNF574,RPL6,LUC7L,CAND1,NSA2,DAP3,MRPL55,HNRNPR,KBTBD7,TRMT10B,RRS1,SNRNP70,HNRNPDL,MRPL13,TERF1,MRPL3,CCDC59,APOL2,ZC3HAV1 |
| 5.880e-11 | -23.56 | regulation of organelle organization | biological process | GO:0033043 | 1212 | 266 | 17256 | 2622 |
PDCD6IP,TSC2,ADD1,CCNB1,PARK7,CDK5,NEK6,RABGAP1L,DNM2,DNMT1,MLST8,BAK1,ERCC1,RHOBTB3,AKT2,MKI67,WDHD1,AURKB,CCNF,MCM2,SLC25A5,STOML2,IWS1,MAP3K4,WAS,MID1IP1,LIMK1,MAP4,OGT,TFDP2,ARRB2,SLF1,MAPRE1,GMFG,PHF23,RHOC,PRKAA1,KCTD17,PARN,LMNA,SPAG5,JMY,PDXP,SMC3,ARPC5,FBXO7,MSH2,PIKFYVE,TERF2,CYFIP1,WDR1,PIP4K2C,CAPZA2,ADRB2,KDM3A,MAP2K2,CCT8,RHOB,XRCC5,SCARB2,PPP3R1,ARAP1,CNOT6,ZNF207,RHOG,ANKRD27,POC1A,PTTG1,ACTR3,RAC1,RMI2,TPX2,TBC1D13,BCL2L1,STMN1,STAM,MOAP1,TERF2IP,SH3BP1,RALB,TBC1D22A,TBC1D14,CDKN1B,TP53BP2,MAVS,CFL1,DCTN1,CCT2,PSRC1,EID1,KAT7,TAOK1,CUL3,WBP2,NUSAP1,PKMYT1,CDC23,TRIM28,CDC16,CHMP4A,NSMCE2,GEN1,ATMIN,MECP2,MAD2L2,CAPN2,CLIC4,HUWE1,CENPJ,AXIN2,CNOT6L,SPTAN1,ZFP64,KAT2A,TCTEX1D2,NEK7,RHOT1,KIF11,MARK2,SH3GLB1,INF2,KIF18A,PARG,STX18,TFDP1,PML,PARP10,YWHAH,ESPL1,ANAPC4,SKA3,KMT2E,SIRT2,UBQLN2,BECN1,ABL2,CDC42,ATG3,NOC2L,CARMIL1,MTPN,TACC3,CDC37,PLK1,SEPT9,NCK1,TLK1,GMFB,EZR,LRP5,ARHGDIB,CDC6,BRCA1,ANLN,OPTN,PAF1,TBC1D17,ATXN2L,ROCK1,CLU,C2CD5,POT1,UBE2D3,TBC1D12,PHB2,CENPF,CIB1,CTCF,CDK13,NCKAP1,RGS2,APOPT1,RB1,VASP,TIGAR,CCP110,CAPZA1,ZNF335,CTR9,BCL2,KNTC1,LRSAM1,MCPH1,PREB,ATP5IF1,CAMSAP1,GBA,RTF1,SEPT7,ARPC1A,DAPK3,TSC1,CDC27,CDCA5,NUP62,YWHAZ,RUVBL2,TMEM14A,WASF2,USP7,CHMP2A,FEZ2,CYLD,DYNLL1,TWF2,MIEF1,HNRNPA2B1,PIN1,AKAP8,PARL,CORO1A,CHTOP,LMAN1,HTRA2,PPIF,UBQLN4,ARHGAP17,RAB7A,WIPF1,BICD2,CHMP2B,VDAC1,USP36,SURF4,UHRF2,XRCC3,CHMP4B,H3F3A,MAPK1,SMURF1,SMAD4,TMEM33,TRIP12,RAE1,CDT1,CDK2AP2,ARFIP2,ARF1,PIP4K2A,FBXO5,KIF5B,NABP2,BRD7,ARHGEF2,H2AFY,ATG13,MYO5A,RNF5,TGFB1,PPP1R9B,RHOA,MIER1,RHOT2,BORA,HSPA1B,MFN2,MAPK3,MTMR3,UPF1,ATAD2,E2F1,KMT2B,UBE2C,TERF1,SLF2,HRAS |
| 5.904e-11 | -23.55 | GSE22886_NAIVE_CD4_TCELL_VS_MEMORY_TCELL_DN | MSigDB lists | GSE22886_NAIVE_CD4_TCELL_VS_MEMORY_TCELL_DN | 183 | 63 | 17377 | 2626 |
TCF12,KARS,ANKRD27,NDUFV2,GLT8D1,HECA,CKLF,RWDD1,SEC61G,ANKH,CBLL1,CREBL2,GLUD1,KCMF1,WRB,PARK7,COPB2,CRKL,FASTKD3,SEC11A,EIF2S2,LRRC8D,DNAAF2,FUT8,GPD1L,TMED2,GINS1,KDM3B,SHOC2,PBXIP1,NCK1,EID1,ERLIN1,CPOX,TLK1,ADSL,CDC6,GALK2,SRSF5,GALNT7,FANCE,ZFR,PRDX1,ARHGAP15,RDH11,GLOD4,SUPT16H,TPD52L2,MID1IP1,RBL1,DCK,HPS5,TBL3,LPCAT4,TBPL1,CAB39,NUP62,MRFAP1L1,YWHAZ,WDR76,TRAF5,N4BP2L2,PDCD4 |
| 5.904e-11 | -23.55 | GSE15930_NAIVE_VS_48H_IN_VITRO_STIM_IL12_CD8_TCELL_DN | MSigDB lists | GSE15930_NAIVE_VS_48H_IN_VITRO_STIM_IL12_CD8_TCELL_DN | 183 | 63 | 17377 | 2626 |
CCNC,TRIM41,CDS2,PDAP1,ALKBH5,MOGS,RRM1,AGPAT3,LACTB2,DTL,FARSA,IRF4,PSMD1,EXOSC7,CLIC4,RNFT1,SIVA1,EFTUD2,RPF2,MDFIC,AHCY,TARDBP,PCYT2,MRPL11,LMAN1,PDIA6,UBE2M,DNMT1,MTX2,NUP85,PPA1,S100A6,CLCN3,POLR2I,NASP,CPOX,PSMA1,RRM2,MRPS10,HTATIP2,SSR2,CDC6,NUSAP1,SMC2,TOMM40,TARS,CDCA4,TIMM13,CDC16,MTHFD2,TFDP1,PGRMC1,ZRANB2,NUP62,KPNA2,SSNA1,RUVBL2,NDUFS5,CDK2,MZT2B,VPS29,GCSH,FUBP1 |
| 6.064e-11 | -23.53 | PCBP1 (poly(rC) binding protein 1) | protein interactions | 5093 | 180 | 65 | 17029 | 2761 |
MIF,UNK,CYLD,EWSR1,UGP2,DYNLL1,TCF3,TKT,TIA1,UBE4A,GNB2,APP,CDC73,LMNA,TIGAR,HUWE1,PPIG,FOXN2,ANP32A,CRY2,TARDBP,UBE3C,TALDO1,ATF2,UBE2M,PABPC1,PCBP2,CFL1,EEF1D,TERF2,CDC37,SRPK2,CDC5L,STAU1,ZCCHC10,RBM42,FAM49B,MAP4K3,BOLA1,PRPF3,BRCA1,PITPNB,ADRB2,PKM,MCM2,GFER,TRIM28,MATR3,SF3A2,SNRPA,CAND1,GLOD4,PDCD6,PML,SRSF3,RUVBL2,ZNF830,CDK2,CD81,SMURF1,IGBP1,POT1,PFKP,ANXA11,FUBP1 |
| 6.120e-11 | -23.52 | protein ubiquitination | biological process | GO:0016567 | 702 | 171 | 17256 | 2622 |
MIB2,UBE2E2,DCAF15,TRIM11,XIAP,CUL1,UBE2Z,UBE2Q1,NHLRC3,UBE2I,BIRC2,RNF103,FBXO22,ZER1,FANCL,PCNA,PSMD1,CDC42,ATG3,FBXW2,MARCH2,RNF26,ASB6,RYBP,PLK1,TRIM8,RBX1,VHL,TOPORS,UBE2V1,USP22,BRCA1,CCNF,CBFB,TRIM4,PAF1,RAD18,RPS27A,PSMD8,TPP2,SOCS4,ARRDC1,KLHL42,FBXL3,ARRB2,PSMC1,ZNF598,DCAF5,UBE2D3,WSB2,RMND5A,ZNRF3,PSMD9,CDC73,DTL,RNF121,UBE2Q2,MED8,KLHL5,MED10,RNFT1,ZNRF2,FBXO7,PPIL2,CTR9,BCL2,FBXL7,RNF135,UBE3C,LRSAM1,SOCS5,UBE2QL1,DCAF8,PSMA1,RTF1,UBE4B,SYVN1,PSMB3,ISG15,PSMC4,CAND1,DERL1,CDC27,KLHL15,SIAH2,DCAF11,VCPIP1,RNF14,RNF139,RNF114,USP7,TRIM41,MPHOSPH8,TRAF7,SUZ12,UBR2,WDTC1,KLHL18,ANKIB1,USP5,PSMA6,MDM2,FBXL6,SIAH1,SOCS6,ANAPC7,TTC3,RNF19A,SPSB3,RNF169,RLIM,PRPF19,BIRC3,PSMA8,RNF25,PSMB7,CUL3,PCGF6,ASB13,CDC23,PSMB9,TRIM28,BTBD1,SOCS7,PEX5,CDC16,PSMD3,UHRF2,RNF38,TRIM32,SMURF1,ZC3HC1,TRIP12,KLHL21,ZFP91,SHPRH,CDCA3,BRAP,CBLL1,UBE4A,WWP2,HERC3,FBXO3,RFWD3,PSMD2,KLHL20,HUWE1,FEM1B,LTN1,UBE3B,FBXL19,UBE2M,RNF5,DCAF6,TNFAIP3,LONRF3,PRKDC,RFFL,FBXO9,ANAPC2,PCGF1,FBXO21,FBXO41,KEAP1,BIRC5,DTX4,KBTBD7,PPP1R11,UBE2C,ANAPC4,DDB1 |
| 6.170e-11 | -23.51 | RPS2 (ribosomal protein S2) | protein interactions | 6187 | 280 | 89 | 17029 | 2761 |
ZNF496,CYLD,NOP2,RPLP2,CHERP,SF3B1,DYNLL1,CUL1,NENF,SND1,RPL11,RPL23A,KRR1,EIF4A3,DNM2,PDCD2,CRY2,TARDBP,CDC37,RPL29,RPL35,AATF,VHL,MRPL12,RPL38,CUL3,TOR1AIP2,BRCA1,UTP3,SLC25A5,MRPS14,RPS9,RPSA,DHX57,CLNS1A,RAD18,HNRNPR,RPS27A,RPS14,U2SURP,RPLP1,H2AFX,ANP32E,COPS6,RRS1,FAU,RPS26,POT1,PDCD2L,NIFK,RPS15,RPL15,ATP5F1B,LMNA,NDUFS4,KRI1,PTEN,RPL17,AHSA1,ZNF746,ATP6V0A2,YBX1,RPL19,FBL,ATP6V0D1,HNRNPM,STAU1,TK1,TEX10,RPS10,RPL8,ILF3,TUFM,ZNF574,RPL6,MRPS10,RPS24,LLPH,SRSF5,RPL27A,RHOT2,CAND1,RPL36,RPL32,DUSP11,RUVBL2,CDK2,CD81,TERF1 |
| 6.257e-11 | -23.49 | GSE33292_WT_VS_TCF1_KO_DN3_THYMOCYTE_DN | MSigDB lists | GSE33292_WT_VS_TCF1_KO_DN3_THYMOCYTE_DN | 196 | 66 | 17377 | 2626 |
TMEM106C,TXN,FOXM1,C5orf30,TPX2,KIF2C,SLC29A1,CCNB1,OAT,OIP5,IARS,DUT,SIVA1,POP7,EFCAB11,AKR1B1,RNASEH2A,TRIM14,PSMG1,CDC6,NUP155,PKMYT1,PRPSAP1,CHAF1A,PRIM1,AHNAK,HSPB11,CERS6,H2AFX,ANP32E,B4GALT2,GCLM,CENPF,DBF4,KIF23,BLM,SPAG5,SLC31A1,GART,EXOSC7,ATIC,BDH1,GTSE1,TIMELESS,AHCY,MDFIC,KNTC1,GINS1,TK1,KAT2A,PRIM2,SIGMAR1,NET1,ABCF2,LDHA,KIF11,AKAP1,MTHFD2,POLE,TFDP1,ACAT1,NDUFS5,UBE2C,ESPL1,TOB1,GCSH |
| 6.275e-11 | -23.49 | REACTOME_MITOTIC_G1_G1_S_PHASES | MSigDB lists | REACTOME_MITOTIC_G1_G1_S_PHASES | 130 | 50 | 17377 | 2626 |
POLA2,MAX,MCM10,CDT1,DBF4,CUL1,ORC1,CCNB1,PSMD9,FBXO5,LIN9,RPA2,CDKN2C,RB1,PSMD2,PCNA,PSMD1,PSMA6,CCNA2,MCM5,CDKN1B,ORC3,PRIM2,MYBL2,PSMB7,E2F3,PSMA1,RRM2,CDC6,PKMYT1,MCM2,PSMB9,PSMB3,PSMC4,RPA1,PRIM1,PPP2CA,POLE,RPS27A,RBL1,PSMD8,PSMD3,E2F4,TFDP1,E2F1,RBBP4,CDK2,E2F2,PSMC1,CDKN2A |
| 6.314e-11 | -23.49 | ILK (integrin linked kinase) | protein interactions | 3611 | 225 | 76 | 17029 | 2761 |
CYLD,UGP2,RAF1,MAGED1,SLC2A1,CUL1,GLUD1,CDIPT,TWF2,FANCI,SSR1,SHC1,ATP2A2,AKAP8,PPP6C,NOC2L,RNF19A,TECR,CLN6,CNNM3,ILKAP,CARM1,TIMM50,CCT2,DPM1,CUL3,HNRNPF,SLC25A22,DNAJA1,PRPSAP1,EML4,TRIM28,DHX15,DDX17,KIF2A,ATP1A1,SEC61A1,NSMCE2,ITGB1,FKBP5,PFKP,HSPH1,EWSR1,PPP1R12A,DNAAF5,NDUFA4,ATP5F1B,LMNA,COPB2,HLA-A,RPN1,ERH,ZNF746,GEMIN4,LPCAT1,SLC12A2,HNRNPM,SLC25A1,PDPK1,TRAFD1,PRKDC,ABCF2,ILF3,RHOT1,VKORC1,RHOT2,CCT8,PICALM,NAP1L1,SLC16A1,DDX5,ATP5F1A,RUVBL2,PDLIM5,ZC3HAV1,FAF1 |
| 6.563e-11 | -23.45 | regulation of biosynthetic process | biological process | GO:0009889 | 4535 | 825 | 17256 | 2622 |
ZBTB10,KDM4A,HEXB,XIAP,CCNL2,EDRF1,RBM4,ZNF275,CDK5,CALM2,USF1,PSMD1,CIPC,THAP4,DNM2,CRY2,NUP153,FNIP2,ECD,SENP1,PLK3,ZNF672,ZNF559,AATF,GABPA,EHMT1,WDHD1,MIER2,TOPORS,ARF4,STOML2,BRMS1,BOLA3,MID1IP1,SMAD2,RPS27A,ZNF689,AXIN1,PRDX5,OGT,VIPAS39,RNASEL,TRIM52,TFDP2,SMAD1,E2F2,ZNF75A,AAAS,PDCD4,SLC25A33,ZNF720,SSRP1,HIVEP3,DHX9,EZH1,EIF2AK4,PSMD9,PARN,CDC73,MCTS1,DDRGK1,TFAP4,SMC3,MEGF8,PHF14,ZNF326,FOXN2,MYDGF,PABPC1,NUP85,NSUN4,CYFIP1,IFRD1,ETV3,FOXK1,RB1CC1,ZMYND11,MTA2,GTPBP4,MYBL2,ITM2A,BCLAF1,CBFA2T2,ELK1,EIF4H,PDLIM1,ETS2,SETD3,CNOT6,ZNF830,SGF29,RNF139,NUP58,EGLN1,ZNF207,RHOG,ZNF296,KARS,SARNP,TRERF1,IVNS1ABP,UBR2,PTTG1,WDTC1,CREBL2,ZNF267,INO80E,SAFB2,RCOR3,TCF19,APP,AHCTF1,ZNF420,SP100,ZKSCAN1,MTA1,GMEB1,NUP107,ZNF226,ANKRD13C,MAVS,ATF2,RBM15,ZC3H3,RPRD1B,CGGBP1,CPNE1,PSRC1,POLR2L,EID1,KAT7,WBP2,RPL38,POLR2D,CIRBP,E2F3,HTATIP2,PFKFB3,MEF2D,TAZ,DDX17,TAF2,PPP2CA,CHCHD3,HIPK2,TICAM1,FUS,ZBTB11,LRP8,USP13,COMMD10,ZNF786,ZNF445,ZFP91,HABP4,TRAK1,JMJD6,GMCL1,ABHD14B,WDR5,ETS1,PMVK,NEXMIF,ZNF92,PPP1R3B,ZBTB45,PSMD2,SUV39H2,PPP1R8,PRDM4,ZNF260,LTN1,ZNF710,GTF2H2,MED22,PDPK1,PPP3CA,TNFAIP3,ZNF512,ZP3,PICALM,ZNF180,ZNF862,KEAP1,GPS2,PITX1,LRPPRC,PML,HMGB2,CD81,PARP10,IGBP1,USF2,YWHAH,THAP5,FAF1,THOC1,AGRN,AAMDC,GPBP1L1,TRIM11,PPP1R15B,FAM129A,RBM8A,CSNK2A1,SND1,BIRC2,CREM,PRNP,LIN9,TET3,PCNA,NUP210,GLIS2,ZNF639,ETV6,PIK3R2,NOC2L,EIF5,MYBL1,MTPN,CCAR1,RYBP,PTPRK,PLK1,SP3,CELSR2,RBX1,PBXIP1,BAZ2A,ZBED5,MRPL12,EZR,CDC6,UBE2V1,LRP5,PBRM1,EAF2,BRCA1,USP21,TONSL,CHD3,ZNF367,E2F4,DVL1,ZNF45,BEND6,FAM208A,POT1,ZNF564,FUBP1,LZTR1,PHB2,CENPF,CTCF,CHCHD2,CDK13,DNAJB1,PPP3CB,RLF,ASXL2,CNOT11,CRLF3,ARID1B,LRRC14,SUB1,RB1,MLX,MED8,TIGAR,MBD2,SSBP3,ZNF746,CTR9,TIMELESS,MDFIC,AFF1,RBM3,ICE2,GLE1,MAML1,PREB,TRAPPC9,ACSL3,LDB1,UTP15,KRAS,EIF2AK1,RTF1,ZNF761,NFATC2IP,EIF4G2,IRF5,ZNF174,PSMC4,RXRB,SYNCRIP,ORMDL2,NLRC5,TBPL1,PRMT7,RUVBL2,USP7,CYLD,TRAF7,ARID2,FOXM1,DYNLL1,ZNF416,DUSP22,GGPS1,PCBP1,COMMD8,ZNF121,VAV1,CSDE1,ZBTB21,NRF1,PDK2,PSMA6,ZNF473,MDM2,KMT5C,ZNF302,PIN1,TARDBP,STRAP,SAP30L,ZNF583,DVL2,KDM3B,TIMP2,POLR2G,ZNF780B,PSMA8,BTG2,PPIE,NUP155,NFATC2,KDM1B,EIF3H,ATP1A1,ZNF700,SCAP,RBL1,MAFK,PSMD3,ZNF436,UHRF2,DNAJC17,NCOA1,H3F3A,SMAD4,ZNF146,BCL2L12,SLC30A9,CTDP1,UNK,MIF4GD,MTERF1,DAP,CDT1,AGO2,ARID5A,GTF3A,HMGN3,NKRF,CDK11B,PAGR1,FZD6,WRNIP1,PTPN2,IRF4,SLC35B4,SS18L1,PTGES3,RBM15B,RPRD1A,RHOA,HMGN5,BTAF1,PRKDC,ZNF202,ZMYM5,PCGF1,TRIM26,BIRC5,TWSG1,L3MBTL3,TFE3,CDCA7L,BBX,E2F1,PKD2,RBPJ,TAF12,NR2F2,PGAM1,HIPK3,IFI16,NUP188,TXN,ZNF496,MAX,H2AFZ,TSC22D3,CXXC1,YTHDF3,UBE2I,EIF1B,COMMD6,MYEF2,PARK7,GLMP,PA2G4,NOL11,FIZ1,ZNF200,TAF5L,MAST2,SMARCE1,DNMT1,ZNF800,SEH1L,CDC5L,SRSF10,ZNF524,KLF10,AKT2,ELOA,DDX20,SUPT20H,AURKB,USP22,CBFB,RFC2,ZMYM3,IWS1,DOT1L,MAP3K4,HHEX,MKNK1,BRD2,PSMD8,RPS14,BTF3,ARRB2,TRAF5,ZNF598,CCDC59,NMD3,HDAC2,PTOV1,SVIP,DDX58,HSPH1,EWSR1,POLR2K,CHTF18,PRKAA1,NOTCH2,PMF1,SUPT7L,ZNF79,PSEN1,ZNF518A,METTL3,VPS25,YY1AP1,CNOT3,JMY,CFLAR,LHX8,MEX3C,KLF16,HDAC7,DAPK1,GNAI2,TNRC18,LPCAT1,EEF1D,TERF2,FDFT1,EIF5A,PHF10,ZNF84,ELL2,ZNF574,USF3,EXOSC9,ARID1A,ADRB2,C9orf40,CYFIP2,FXR1,KDM3A,MAP2K2,CCT8,PSMB3,PHF6,XRCC5,CAT,PFDN5,EPRS,ZNF777,SERTAD2,GOLGA2,EPOP,ZFP92,RBMX,QARS,MED15,CEBPG,PPP3R1,PIAS2,SAMD8,TCOF1,YY1,MAP3K5,RNF14,CDK2,CDKN2A,ZNF511,NDC1,DNMT3A,ATXN3,RWDD1,ZBTB37,RPS6KA1,RAF1,SUZ12,EIF3D,RAC1,MAGED1,PAIP2,TERF2IP,SPINDOC,CCNA2,ZNF75D,SHC1,KDM2A,UCHL5,LPIN2,MRPS27,CDKN1B,CDK12,SAP30,CCT2,BRD4,RFC3,ERF,CDC123,DRAP1,CUL3,ELP4,EDF1,H2AFV,PSMB9,ERC1,TRIM28,SERP1,CENPU,PRDM11,SUPT16H,EIF3K,VEZF1,ZNF282,HINT1,CERS6,SAFB,STAT1,H2AFX,ATF6,TRIM32,BEND3,EYA2,ATMIN,RHEBL1,POU3F2,NCOR2,DEPDC1,MECP2,TCF3,ARGLU1,SECISBP2,MYNN,BLM,POFUT1,FOXO3,HMG20A,MAD2L2,WWP2,GTF2F1,CCNK,PTEN,ELP5,CARF,CITED2,CREB1,CNOT6L,NCOA2,TSHZ1,ZFP64,KAT2A,NEK7,WDR18,ILF3,PARP4,RFXANK,COMMD4,KLF6,FADD,POLR2A,CBX3,PRDX3,ZHX1,TFDP1,KHSRP,DDX5,BRWD3,TAF6,CPEB2,PURA,FAM83G,RORB,ZBED3,CCNC,ZNF76,IER2,NOP2,HNRNPAB,UBN1,NF1,KMT2E,DNAJC24,PTP4A3,ZNF107,TAF6L,SIRT2,COMMD5,MAPK14,SNAPC4,ZNF696,RAP1A,EIF4A3,METTL14,JAZF1,PHTF1,SRI,ZBTB22,TCEA1,OGG1,ARID4A,TRIM14,CARM1,ELOF1,DEAF1,TRIM8,NCK1,VHL,RIOX2,RRM2,SOX4,KMT2C,ASF1B,PAF1,GEMIN5,UBTF,EIF4ENIF1,BRWD1,PQBP1,BAZ1B,ZNF268,STK11,CHEK2,CLU,PSMC1,UBE2D3,PPP1R12A,ZNF768,NACA,CIB1,MED13L,TIA1,MEF2A,THRAP3,RGS2,TTF1,SRRT,NUP205,LYAR,NFATC3,ZNF449,MED10,ZNF335,BUD31,BCL2,YBX1,ACAD8,MCPH1,ZNF189,HP1BP3,VOPP1,CREG1,ERLIN1,CIC,RPL6,GBA,PSMA1,EIF2A,SLTM,DAPK3,CAND1,TSC1,NFIL3,SIAH2,NUP62,ZFP90,RBBP4,HNRNPDL,TOB1,N4BP2L2,ZBTB24,SMARCD1,ADNP2,TCF12,MBD1,ASH1L,MPHOSPH8,SMARCA4,PLAGL2,NSD3,IRF3,ORC1,CHD1,MEAF6,MXD1,PAIP1,HNRNPA2B1,SAP130,RRN3,NVL,AKAP8,CHTOP,F2R,UTP4,ZNF770,RLIM,MOSPD1,CHP1,POU2AF1,FAM172A,ZNF500,PGGT1B,RNF25,PCGF6,PSMB7,NLN,ATXN1,BOLA1,GLO1,ERBIN,MBD3,RPS9,PDHX,ZNF317,TAB2,HNRNPR,TULP3,STAT6,ARNTL,SCARB1,AKNA,SMURF1,MAPK1,BRD9,CBX4,NAT14,DNAJC2,ZNF316,RAE1,EYA1,SCYL1,NUP54,DBF4,KLF13,PAWR,MXD4,FBXO5,FASTKD3,KMT5A,PELO,NABP2,H2AFY,ANP32A,BRD7,ARHGEF2,STAT3,TGFB1,SAMD4B,ELOVL5,PHF20L1,COA3,DCAF6,HMGN1,PSPC1,MIER1,RCOR1,PRMT2,MEN1,ZNF407,CDK11A,MAPK3,TFEB,HSPA1B,CNOT9,LEMD2,UPF1,ATAD2,KMT2B,ZRANB2,CENPT,ZMIZ1,HRAS,TERF1 |
| 6.647e-11 | -23.43 | CROONQUIST_NRAS_SIGNALING_DN | MSigDB lists | CROONQUIST_NRAS_SIGNALING_DN | 71 | 34 | 17377 | 2626 |
FOXM1,PTTG1,TPX2,PTP4A3,KIF2C,CCNB1,STMN1,SPAG5,OIP5,PCNA,CCNA2,DUT,KIF22,EIF5,SMC4,PLK1,GINS1,RFC3,TK1,NASP,MYBL2,MKI67,CDC6,SMC2,AURKB,MCM2,KIF11,CHAF1A,RAD51C,H2AFX,HMGB2,CHEK2,CCNB2,UBE2C |
| 6.834e-11 | -23.41 | GO_PEPTIDE_METABOLIC_PROCESS | MSigDB lists | GO_PEPTIDE_METABOLIC_PROCESS | 537 | 138 | 17377 | 2626 |
MRPS15,EIF1B,BECN1,RBM4,MRPL19,PABPC4,SLC25A37,RPL23A,EEF2K,EIF5,MRPL32,PCBP2,LARS,HARS,MRPL12,MRPL43,SLC25A22,SLC25A5,EIF3A,RPL37,RPS27A,RPS14,EIF2D,MRPL27,IARS2,QRSL1,MRPL13,RPS26,SLC25A33,RPS15,MRPL9,MRPS2,DHPS,NACA,GSPT2,RPL15,PCSK7,EIF2AK4,PSEN1,MCTS1,EIF2S2,EFTUD2,MRPL48,MRPL40,MRPL21,PABPC1,PPA1,EEF1D,CARS2,EIF5A,EIF3L,NOA1,DHX29,RPS10,RPL6,RPS24,MRPL16,EIF2A,EIF4H,EIF4G2,ABCF1,RPL36,EPRS,QARS,MRPL3,KARS,RPLP2,MRPL39,EIF3D,SLC25A44,PAIP1,RPL11,MRPL50,SEC11A,FARSA,IARS,MRPL34,MRPS27,RPL29,RPL35,CDC123,RPL38,NLN,GLO1,NDUFA7,POLG2,MRPS14,RPS9,EIF3G,EIF3H,RPSA,EIF3K,MRPL2,DAP3,IDE,MRPL55,CHCHD1,FTSJ1,RPLP1,PPA2,FAU,LTA4H,SLC25A39,PDF,GCLM,RPS2,MRPL42,MRPS26,SLC25A12,SECISBP2,CHAC2,SLC25A43,GFM2,SLC25A36,SPPL2A,GSTK1,CLIC4,GATC,RPL17,RRBP1,MRPL54,RPL19,MRPL11,GTF2H2,RPL22L1,SLC25A1,RPL8,TUFM,MRPS10,RPL27A,HAGH,GUF1,SPPL2B,TARS,RPL32,SLC25A19,SPCS3,CPEB2 |
| 6.993e-11 | -23.38 | OTUB1 (OTU deubiquitinase, ubiquitin aldehyde binding 1) | protein interactions | 55611 | 213 | 73 | 17029 | 2761 |
KARS,IMMT,UBE2E2,TXN,FOXM1,FLYWCH2,LAGE3,CSNK2A1,EBNA1BP2,CCNB1,PCBP1,SDHA,BIRC2,EPM2A,CRKL,ZBTB21,PCNA,EIF4A3,PIN1,TXLNA,TARDBP,MAVS,TCEA1,MTPN,ILKAP,GPX4,SEC61B,BIRC3,DNAJA1,SLC25A5,USP21,HSPA4,SMAD2,PRDX5,MAP4,H2AFX,UQCRH,ACTB,FUS,MAPK1,SMAD4,UBE2D3,GCLM,EWSR1,RRM1,NDUFA4,FAM136A,ZNF746,MSH2,CTPS1,SLC27A4,PPA1,LUC7L2,SLC25A1,NUDC,RHOA,DDX24,TRIR,ABCF2,RFFL,ADSL,MPG,ABCF1,PRDX1,DDX23,MAGED2,SDHB,PGRMC1,SLC16A1,DDX5,ASNA1,IDH3B,VPS29 |
| 7.140e-11 | -23.36 | PENG_RAPAMYCIN_RESPONSE_DN | MSigDB lists | PENG_RAPAMYCIN_RESPONSE_DN | 227 | 73 | 17377 | 2626 |
SRM,CCNC,RAB14,CHERP,TMEM109,UCK2,EBNA1BP2,SLC29A1,BCAP31,PAPOLA,FARSA,GOT2,POP7,APOOL,PDIA6,GM2A,PRPF19,PPIF,CCT2,AATF,IDH3A,MRPL12,GLO1,DNAJA1,PITPNB,RAB1A,TXNL4A,DAP3,HSPA4,PSMD8,TIMM17A,SAFB,ATP6V0C,RPS26,ATP6V0E1,PPIB,RAE1,CYCS,ARF1,COPB2,TFRC,EBP,AHSA1,FAM89B,PTGES3,LPCAT1,UBE2M,TMED2,LDHB,TXNL1,STAU1,KAT2A,MAPKAPK3,AMD1,WDR18,JTB,EMP3,USP10,GORASP2,CAPZA2,TOMM40,EIF4G2,PICALM,TARS,SDHB,POLR2J,SYNCRIP,PRDX3,TATDN2,IDH3B,PGAM1,PTDSS1,BYSL |
| 7.166e-11 | -23.36 | WHITEFORD_PEDIATRIC_CANCER_MARKERS | MSigDB lists | WHITEFORD_PEDIATRIC_CANCER_MARKERS | 111 | 45 | 17377 | 2626 |
PTTG1,CENPF,DBF4,TPX2,CDCA8,NUF2,CCNB1,STMN1,PCNA,CCNA2,MCM5,KIF14,PRC1,RNASEH2A,DNMT1,SMC4,MND1,TK1,SNRNP200,RFC3,NASP,PBK,MYBL2,MKI67,ILF3,CCDC34,RRM2,NUSAP1,CDCA2,SOX4,KIF11,ODC1,ASF1B,MFN2,ATAD2,BIRC5,ZNF367,CDCA5,H2AFX,E2F1,KPNA2,UBE2C,CCNB2,ESPL1,POLQ |
| 7.187e-11 | -23.36 | ribonucleoprotein complex export from nucleus | biological process | GO:0071426 | 122 | 48 | 17256 | 2622 |
RPS15,NDC1,NUP188,CDC40,SARNP,THOC1,SRSF6,RAE1,RBM8A,ALKBH5,NUP54,AGFG1,NUP205,HNRNPA2B1,NUP210,EIF4A3,SRSF4,NUP107,UPF2,NUP153,GLE1,CHTOP,CPSF4,ZC3H3,NUP85,SEH1L,SRSF11,EIF5A,FYTTD1,NXT1,POLR2D,RNPS1,SLBP,NUP155,SRSF5,DDX39A,SYMPK,RPSA,SRSF1,TSC1,HHEX,UPF1,NUP62,SRSF3,RRS1,NUP58,NMD3,AAAS |
| 7.188e-11 | -23.36 | GSE17721_0.5H_VS_4H_CPG_BMDC_UP | MSigDB lists | GSE17721_0.5H_VS_4H_CPG_BMDC_UP | 188 | 64 | 17377 | 2626 |
TRIM41,MMACHC,GGNBP2,ADD1,NOP2,ADAM10,UCK2,LAGE3,ATG3,TBC1D14,SPTSSA,SLC35C2,DNMT1,TIMM50,SRPK2,ADCY7,RRM2,AURKB,MCFD2,KIF2A,MKNK1,MYO18A,QRSL1,ARRDC1,PDXK,SLC25A39,NCOR2,LZTR1,MANBA,CUTA,CIB1,MRPS26,SMC6,EPN1,HAUS4,TOP2B,MYO9B,SDF2L1,GOLM1,SMC3,NFATC3,AHSA1,CRAT,TPCN1,PHKG2,IMPA2,VOPP1,MLEC,POLR2I,HEMK1,GALC,ERLIN1,KIAA0930,PPP1R21,PIP4K2C,UHRF1BP1,HAUS8,RPA1,PDCD6,KIF18A,DUSP3,APPL2,SSNA1,TMEM131 |
| 7.266e-11 | -23.35 | PUF60 (poly(U) binding splicing factor 60) | protein interactions | 22827 | 134 | 53 | 17029 | 2761 |
ZNF207,CCNC,EWSR1,UGP2,SF3B1,OLA1,LAMTOR3,JMJD6,ARGLU1,THRAP3,UBE2I,PCBP1,PABPC4,PAPOLA,SIAH1,ZNF746,RAD23B,KHDC4,UPF2,MRM3,PABPC1,HNRNPM,ABCC1,NUDC,SRSF11,SF3B6,RPL6,HNRNPF,RNPS1,CUL3,SREK1,MCM2,EIF4H,MATR3,SF3A2,TARS,CAND1,SYNCRIP,RBM25,CHD3,AXIN1,HNRNPH3,PPM1G,MYO18A,UHRF2,MPV17,KHSRP,H3F3A,CDK2,DDB1,FAF1,VPS29,FUBP1 |
| 7.361e-11 | -23.33 | nuclear export | biological process | GO:0051168 | 158 | 57 | 17256 | 2622 |
RPS15,NDC1,NUP188,CDC40,SARNP,THOC1,SRSF6,RAE1,RBM8A,ALKBH5,NUP54,AGFG1,XPO7,NUP205,HNRNPA2B1,ANKLE1,NUP210,EIF4A3,SRSF4,NUP107,UPF2,NUP153,GLE1,CHTOP,AHCYL1,CPSF4,ZC3H3,NUP85,SEH1L,CHP1,SRSF11,TGFB1,EIF5A,FYTTD1,NXT1,POLR2D,RNPS1,SLBP,ATXN1,NUP155,NUTF2,SRSF5,DDX39A,SYMPK,LSG1,RPSA,SRSF1,HHEX,TSC1,UPF1,NUP62,SRSF3,RRS1,SMURF1,NMD3,NUP58,AAAS |
| 7.670e-11 | -23.29 | GSE17721_POLYIC_VS_PAM3CSK4_8H_BMDC_DN | MSigDB lists | GSE17721_POLYIC_VS_PAM3CSK4_8H_BMDC_DN | 184 | 63 | 17377 | 2626 |
RECQL,TP53RK,NOP2,MRPS2,PRKCSH,KLHL21,SNX15,STARD7,GTF3A,NCKAP1,PDXDC1,POLR3K,XPR1,SEC11A,C18orf32,INTS7,UTP18,CRAT,BANF1,ARHGEF1,MEA1,BTF3L4,GEMIN6,NDUFS8,NAP1L4,UBE2M,NUP85,GM2A,PREB,PRPF19,EIF3L,FTL,ADAM17,ZFP64,AATF,RBX1,ASPM,IDH3A,SNRPB,PSMB7,C9orf40,ARPC1A,NDRG3,LUC7L,EIF4H,COMMD4,MBD3,TSR2,DHX15,SUPT16H,CDKN2AIPNL,KPNA1,ATP1A1,SYNCRIP,ORMDL2,TTC13,FASTK,PRDX5,FAM122A,HRAS,CPEB2,SSSCA1,BYSL |
| 7.713e-11 | -23.29 | MODULE_3 | MSigDB lists | MODULE_3 | 380 | 106 | 17377 | 2626 |
TMEM106C,RHOG,IMMT,NQO1,UBN1,FOXM1,SUZ12,PTTG1,UCK2,TPX2,SMARCA4,SLC29A1,GYG1,CCNB1,STMN1,BIRC2,MBD4,SSR1,KIFC1,SEC11A,PCNA,CCNA2,DNM2,AP1M1,CDC25B,F2R,DNMT1,PTPRK,PRPF19,PLK3,PLK1,ERF,CDC123,MAP4K4,PSMB7,MRPL12,GMFB,VDAC2,RRM2,PSMG1,ARHGDIB,AURKB,SOX4,CCNF,MCFD2,MCM2,PRPSAP1,CHAF1A,DPYSL3,PON2,TRAM2,DAP3,IARS2,H2AFX,ADAM9,PPP5C,MAPRE1,EWSR1,SRGN,DHX9,RRM1,SLC4A2,TMED3,UBE4A,ITGB5,RAB11A,TFRC,NUP205,EBP,ATIC,MCM5,PPP4R1,UBE3C,CITED2,LPCAT1,UBE2M,TMX1,SLC25A1,SMC4,FDFT1,STAU1,CYFIP1,TK1,ILF3,MYBL2,EMP3,TOMM40,KIF11,ARPC1A,ABCF1,ZDHHC3,FADD,PSMC4,CBX3,RPA1,NAP1L1,UAP1,TFDP1,MAPK6,CDK2,UBE2C,CCNB2,PDLIM5,MRPL3,BYSL,IFI16 |
| 8.609e-11 | -23.18 | CSNK2A1 (casein kinase 2 alpha 1) | protein interactions | 1457 | 523 | 142 | 17029 | 2761 |
MAX,ALKBH5,CSNK2A1,SND1,USP48,MAPK14,CREM,SF3B2,PRNP,CDC25B,ECD,EIF5,LRRC59,FTSJ3,SRSF10,CDC37,RYBP,VHL,GMFB,SREK1,BRCA1,MCM2,LUC7L,MAK16,CLNS1A,IWS1,UBTF,PAF1,WAS,BRD2,CHD3,C1orf109,OGT,STK11,DVL1,ARRB2,NMD3,PDCD4,HDAC2,SSRP1,UBE2D3,HSPH1,PPP1R2,GGA1,DNAJB2,THRAP3,SRRT,WDR48,LMNA,FBRS,SUB1,MLX,EIF2S2,RBM34,CTR9,YBX1,MDFIC,LUC7L2,EEF1D,ABCC1,SRSF11,IFRD1,RPL6,PIP4K2C,RTF1,EXOSC9,BCLAF1,FXR1,ISG15,XRCC5,NAP1L1,RBMX,DTD1,GPI,ATP5F1A,TCOF1,SNRNP70,RBBP4,HNRNPDL,SF3B1,MYH9,STMN1,APP,HNRNPA2B1,NRF1,MDM2,UTP18,WDR44,PIN1,AKAP8,CLTB,PDIA6,ATF2,DVL2,RNPS1,CIRBP,PCGF6,SLBP,FKBP3,EIF3H,SUPT16H,DDX17,HSPA4,DHX16,SAFB,H2AFX,RPLP1,EFCAB14,XRCC4,NKAPD1,MAPK1,ABCA1,CBX4,CTDP1,PDAP1,HDGFL2,PIP4K2A,GTF2F1,RBM17,ERH,PTEN,PPP1R8,NAP1L4,MSH6,PPAN,DDX24,PRKDC,BMS1,PACS1,RANGAP1,CDK11A,POLR2A,INF2,KPNA4,CCDC6,ZHX1,MFAP1,PML,ZRANB2,BRWD3,FAF1,IFI16 |
| 8.652e-11 | -23.17 | FUJII_YBX1_TARGETS_DN | MSigDB lists | FUJII_YBX1_TARGETS_DN | 193 | 65 | 17377 | 2626 |
POLA2,UBL3,FOXM1,TCF19,FANCI,SSR1,OIP5,CD3EAP,DUT,RAD23B,RNASEH2A,SLC26A2,MYBL1,CLCN3,RFC3,SLC16A7,RRM2,NUSAP1,CDC6,BRCA1,CDC23,MCM2,CCNF,SHCBP1,ODC1,H2AFV,ASF1B,RAD54B,CHAF1A,PRIM1,ZNF367,NRM,H2AFX,XRCC3,SSRP1,MCM10,DEPDC1,TRIO,CDT1,RRM1,KIF23,METTL3,MAD2L2,FBXO5,DTL,MCM5,EI24,TIMELESS,TK1,PRKDC,ASPM,RDH10,MYBL2,UBE4B,PDE3B,KIF11,MASTL,ATAD2,TWSG1,NEIL3,ODF2,SLC25A19,NUP62,YWHAH,CDK2 |
| 8.652e-11 | -23.17 | GSE28726_NAIVE_VS_ACTIVATED_CD4_TCELL_DN | MSigDB lists | GSE28726_NAIVE_VS_ACTIVATED_CD4_TCELL_DN | 193 | 65 | 17377 | 2626 |
MIF,TMEM106C,SRM,KIF3B,MMACHC,PTMS,HSPH1,TRIP10,CENPF,PTTG1,TPX2,PLAGL2,EBNA1BP2,CCNB1,TWF2,PMVK,MRPL19,FANCI,FANCL,IRF4,PCNA,CCNA2,PSMA6,GATC,MCM5,BDH1,AHCY,AHCYL1,SAP30,GINS1,CYFIP1,NRAS,RAD51AP1,MKI67,LDHA,MYBL2,RRM2,SEPT8,WDHD1,PSMG1,CDC6,AURKB,BRCA1,SMC2,TOMM40,MCM2,PSMB9,KIF11,PRDX1,PSMB3,MAT2A,HMGN2,PRDX3,DBI,NFIL3,COX8A,ACAT1,RGL1,PDXK,RUVBL2,GPI,RNF14,UBE2C,CCNB2,ESPL1 |
| 8.842e-11 | -23.15 | GO_GOLGI_MEMBRANE | MSigDB lists | GO_GOLGI_MEMBRANE | 667 | 163 | 17377 | 2626 |
RAB14,TMED7,COPA,GXYLT1,TGOLN2,CDIPT,SEC16A,SYNRG,RAB8A,ASAP2,CDC42,RAB35,AP1M1,DNM2,TFG,RHBDD2,MGAT5,PGAP2,USO1,RHOBTB3,TMEM115,NRAS,APH1A,PITPNB,GALNT7,MCFD2,STX16,SLC50A1,RAB2B,RHEB,OPTN,MAN2A2,TMED10,MYO18A,ST3GAL2,GALNT10,ROCK1,CLN3,CHPT1,CHPF2,RTN3,NAA60,B4GALT2,SVIP,SCOC,GORASP1,AGTRAP,HLA-E,PCSK7,B4GALT1,TMED3,RAB6A,NOTCH2,SLC35B1,B4GALT4,PSEN1,TMEM165,QSOX2,COPG2,COPB2,CD59,RNF121,C1GALT1,TPST1,PIKFYVE,LPCAT1,PPP6R1,TMED2,KDELR1,PREB,NAGPA,CYTH1,TRAPPC9,MFNG,GORASP2,GOSR1,ZDHHC3,SEC31A,GNAS,GOLGA4,GALNT2,GOLGA2,NSF,ARAP1,ZDHHC7,SMPD4,PPP6R3,CORO7,SYS1,GNPNAT1,SLC2A1,COPE,GPR89A,RAC1,VTI1A,SLC39A13,SLC35B2,AP1B1,BCAP31,APP,EXT2,ANKRD28,RAB21,PPP6C,CLTB,LMAN1,GCC1,EBAG9,CLCN3,GOPC,CUL3,PKMYT1,RAB1A,AP4E1,ERC1,SURF4,SCAP,GOLGA8A,CANT1,AP1S1,ATF6,B4GALT3,CSNK1D,GOLIM4,GOLPH3L,SCAMP3,TMBIM4,B4GALT5,SRGN,SCYL1,VPS45,ARFIP2,AGPAT3,ARF1,HLA-A,MAN1A1,SPPL2A,PDCD10,SEC24C,FUT8,SLC35B4,ZDHHC13,ST8SIA2,SLC35A1,MOB4,B3GALT6,ATP2C1,COG1,RFFL,PNPLA8,SPPL2B,SH3GLB1,YIF1A,HLA-B,NUCB1,SEC23IP,GOLGA7,SNAP29,STX18,GLG1,HRAS,GPR89B,SNAPIN |
| 9.127e-11 | -23.12 | GSE13547_WT_VS_ZFX_KO_BCELL_ANTI_IGM_STIM_2H_UP | MSigDB lists | GSE13547_WT_VS_ZFX_KO_BCELL_ANTI_IGM_STIM_2H_UP | 172 | 60 | 17377 | 2626 |
COX5B,IMMT,MCM10,RRP15,CDCA3,RRM1,KIF23,RACGAP1,PMF1,STMN1,GTF2F1,DTL,PA2G4,UCHL5,PPP1R8,BANF1,NAA50,RPF2,YBX1,RBM3,AHCY,TAGLN2,MTPN,TACC3,TIMM50,SRP72,HARS,EMB,POLR2D,CIRBP,RRM2,KCTD20,CDC6,UBE2V1,EXOSC9,CAPZA2,EIF2A,LY6E,MRPS14,PDHX,SNRPA,CLNS1A,AKAP1,HMGN2,ADSS,UTP20,EPRS,PLAA,BIRC5,NRM,DBI,LRPPRC,AP1S1,FKBP5,KLHDC4,WDR76,PGAM1,CCNB2,PSMC1,DDX52 |
| 9.210e-11 | -23.11 | nucleobase-containing compound transport | biological process | GO:0015931 | 227 | 73 | 17256 | 2622 |
NDC1,TOMM20,NUP188,SARNP,THOC1,RBM8A,ALKBH5,SLC29A1,SLC35B2,AGFG1,HNRNPA2B1,AHCTF1,NUP210,SNUPN,EIF4A3,SRSF4,NUP107,NUP153,CHTOP,SLC35C2,ZC3H3,SEH1L,FYTTD1,NXT1,POLR2D,RNPS1,SLBP,NUP155,BICD2,NUTF2,SLC25A5,RPSA,SRSF1,IWS1,HHEX,RRS1,NMD3,AAAS,SLC25A33,NXT2,RPS15,CDC40,RAE1,SRSF6,NUP54,FLOT1,DHX9,SLC35B1,XPO7,NUP205,SLC25A36,SLC35B4,UPF2,GLE1,CPSF4,MVP,SLC35A1,NUP85,SRSF11,EIF5A,SRSF5,TMEM241,DDX39A,SYMPK,NPIPA1,TSC1,UPF1,LRPPRC,SLC25A19,KHSRP,NUP62,SRSF3,NUP58 |
| 9.247e-11 | -23.10 | nuclear division | biological process | GO:0000280 | 290 | 87 | 17256 | 2622 |
BCCIP,ZNF207,CHMP2A,NDC1,PDCD6IP,UBR2,PTTG1,ACTR3,XIAP,TPX2,NUF2,KIF2C,CCNB1,BECN1,BIRC2,MIS12,KIFC1,ANKLE1,ABRAXAS2,KIF14,AKAP8,XRCC2,PDS5B,KIF22,CDC25B,MYBL1,SEH1L,PLK1,MND1,PSRC1,BIRC3,CUL3,TUBGCP5,NUSAP1,SMC2,AURKB,CHMP2B,CDC23,RAD54B,KIF2A,RAD51C,CHMP4A,DSN1,KIF18B,CEP55,CHMP4B,XRCC3,CHEK2,VPS4A,RRS1,PPP2R2D,RAD51D,KIF3B,CTDP1,MZT1,PHF23,CDT1,CDCA8,KIF23,TOP2B,RACGAP1,SPDL1,NCAPG,RAB11A,TUBGCP2,SPAG5,FBXO5,RB1,PRC1,NAA50,SMC4,RHOA,ASPM,MYBL2,KIF11,MASTL,LEMD2,KIF18A,GOLGA2,BIRC5,CDCA5,NUP62,NDE1,UBE2C,CHMP7,ESPL1,TERF1 |
| 9.286e-11 | -23.10 | GSE10239_MEMORY_VS_KLRG1HIGH_EFF_CD8_TCELL_DN | MSigDB lists | GSE10239_MEMORY_VS_KLRG1HIGH_EFF_CD8_TCELL_DN | 189 | 64 | 17377 | 2626 |
RAB14,MRPL39,ACTR3,TMEM97,NIPA2,NHLRC3,KCMF1,BCAP31,KIFC1,LIN9,RAB21,GRSF1,LPIN2,PDS5B,TRA2B,KIF22,METTL9,ATF2,SRSF10,CPNE1,IDH3A,CYP20A1,SLBP,AURKB,DIDO1,MCM2,ANLN,SERP1,ASF1B,PON2,RAD51C,IDE,CDCA4,TMED10,SOCS4,CHMP4B,E2F2,RTN3,DHPS,C1orf112,CENPF,LAMTOR3,KIF23,GMCL1,AP3S1,FASTKD3,SNX18,PRC1,SLC12A2,SGCB,MYO5A,FDFT1,ALDH9A1,TK1,NUDT4,PSPC1,FBXO9,CCDC34,CBX3,CAT,SEC23IP,PARG,YWHAZ,BTBD10 |
| 9.664e-11 | -23.06 | GNF2_MLH1 | MSigDB lists | GNF2_MLH1 | 40 | 24 | 17377 | 2626 |
CCT2,KARS,H2AFZ,MRPL42,SLBP,SNRPD3,FANCI,SRSF1,CBX3,SUPT16H,HNRNPA2B1,PA2G4,SMC3,RBMX,U2SURP,MSH2,NUP107,LRPPRC,NUP153,KNTC1,PTGES3,RBBP4,MSH6,SSRP1 |
| 9.664e-11 | -23.06 | GNF2_UBE2I | MSigDB lists | GNF2_UBE2I | 40 | 24 | 17377 | 2626 |
ZNF207,KARS,EIF3L,RPS15,POLR2G,EIF3D,SUMO2,UBXN1,RPL8,HNRNPF,PSMA1,RPL15,UBE2I,RBM4,SERP1,EIF3K,QARS,RPS14,TRA2B,RPL19,BTF3,SRSF3,FBL,SMNDC1 |
| 9.881e-11 | -23.04 | mRNA Processing | WikiPathways | WP411 | 132 | 51 | 5312 | 837 |
CDC40,HNRNPAB,SRSF6,SF3B1,DHX9,DHX8,SNRPD3,METTL3,PRPF18,SF3B2,PAPOLA,RBM17,HNRNPA2B1,DNAJC8,EFTUD2,SRSF4,TRA2B,YBX1,CPSF4,HNRNPM,PCBP2,CSTF1,SRSF10,SRPK2,SNRPB,SUGP2,RNPS1,SREK1,DDX20,PRPF3,SRSF5,PRMT2,TXNL4A,SF3A2,POLR2A,SNRPA,DHX15,SRSF1,SUGP1,CLK3,DHX16,HNRNPR,TMED10,RBMX,PPM1G,PRPF4,SRSF3,FUS,SNRPG,SNRNP70,PRPF4B |
| 1.002e-10 | -23.02 | GNF2_BUB1B | MSigDB lists | GNF2_BUB1B | 49 | 27 | 17377 | 2626 |
GINS1,PLK1,NASP,HJURP,ASPM,MRPL39,RRM1,CDCA8,RRM2,RACGAP1,AURKB,MCM2,KIF11,NUP205,FANCI,SPAG5,ASF1B,PA2G4,PCNA,CCNA2,KIF14,CEP55,CENPM,CCNB2,UBE2C,ESPL1,SMC4 |
| 1.002e-10 | -23.02 | MORF_BUB1 | MSigDB lists | MORF_BUB1 | 49 | 27 | 17377 | 2626 |
PLK1,IMMT,RFC3,H2AFZ,FOXM1,TPX2,RRM1,CYCS,KIF2C,CCNB1,VDAC1,KIF11,TARS,HDDC2,SPAG5,SRSF1,IARS,GOT2,MFAP1,KIF14,TFDP1,EI24,BAZ1B,KHSRP,ESPL1,HDAC2,NUDC |
| 1.007e-10 | -23.02 | ribonucleoprotein complex localization | biological process | GO:0071166 | 123 | 48 | 17256 | 2622 |
RPS15,NDC1,NUP188,CDC40,SARNP,THOC1,SRSF6,RAE1,RBM8A,ALKBH5,NUP54,AGFG1,NUP205,HNRNPA2B1,NUP210,EIF4A3,SRSF4,NUP107,UPF2,NUP153,GLE1,CHTOP,CPSF4,ZC3H3,NUP85,SEH1L,SRSF11,EIF5A,FYTTD1,NXT1,POLR2D,RNPS1,SLBP,NUP155,SRSF5,DDX39A,SYMPK,RPSA,SRSF1,TSC1,HHEX,UPF1,NUP62,SRSF3,RRS1,NUP58,NMD3,AAAS |
| 1.015e-10 | -23.01 | establishment of chromosome localization | biological process | GO:0051303 | 75 | 35 | 17256 | 2622 |
CHMP2A,PDCD6IP,CDT1,CENPF,ACTR3,CDCA8,NUF2,KIF2C,CCNB1,SPDL1,BECN1,RAB11A,MIS12,KIFC1,ANKLE1,KIF14,KIF22,SEH1L,PSRC1,CUL3,CDC23,CHMP2B,LEMD2,CHMP4A,KIF18A,CDCA5,CEP55,FAM83D,NUP62,CHMP4B,VPS4A,RRS1,NDE1,CHMP7,TERF1 |
| 1.018e-10 | -23.01 | GO_REGULATION_OF_PROTEIN_MODIFICATION_BY_SMALL_PROTEIN_CONJUGATION_OR_REMOVAL | MSigDB lists | GO_REGULATION_OF_PROTEIN_MODIFICATION_BY_SMALL_PROTEIN_CONJUGATION_OR_REMOVAL | 269 | 82 | 17377 | 2626 |
XIAP,CUL1,CCNB1,BIRC2,PARK7,FANCI,FBXO22,ZER1,CDK5,UBXN2A,PSMD1,PSMA6,MTA1,PIN1,ANAPC7,PDCL3,PLK1,BIRC3,PSMA8,PSMB7,TOPORS,BRCA1,DNAJA1,DCUN1D5,SOX4,CDC23,RAB1A,PSMB9,TOLLIP,CDC16,RPS27A,PSMD8,PSMD3,AXIN1,LIMK1,OGT,TICAM1,XRCC3,CLU,SMURF1,ARRB2,GEN1,PSMC1,TRIP12,GORASP1,PHF23,DNAJB2,UBXN1,DCUN1D4,PSMD9,PSEN1,MAD2L2,WDR48,FBXO5,FKBP1A,PSMD2,PTEN,CTR9,FEM1B,TNFAIP3,GTPBP4,PSMA1,ANAPC2,ADRB2,PTTG1IP,ISG15,PSMB3,HSPA1B,MASTL,PSMC4,DERL1,HSPBP1,GOLGA2,CDC27,SIAH2,PML,CDK2,PARP10,UBE2C,RNF139,CDKN2A,ANAPC4 |
| 1.024e-10 | -23.00 | GNF2_DAP3 | MSigDB lists | GNF2_DAP3 | 112 | 45 | 17377 | 2626 |
ZNF207,KARS,RPS2,RWDD1,EIF3D,SUMO2,NACA,GTF3A,SNRPD3,PAPOLA,RPL23A,NOL11,RPL17,PPP1R8,PPP6C,TRA2B,RPL19,TARDBP,FBL,RBM15,SRP72,IFRD1,EIF3L,SNRNP200,RPL38,RPL6,PSMA1,RPS24,UTP3,RPL27A,DDX39A,DHX15,RPSA,SRSF1,NSA2,RPL37,EIF3K,DAP3,RPL32,HNRNPR,QARS,RBMX,SRSF3,BTF3,CCDC59 |
| 1.044e-10 | -22.98 | ACLY (ATP citrate lyase) | protein interactions | 47 | 68 | 34 | 17029 | 2761 |
PRKAB1,SIRT2,PRKACA,SDHA,APP,SRRT,SHC1,HUWE1,AHSA1,ZNF746,NUP107,CS,PPP6C,CRY2,EEF1D,TERF2,STAU1,CUL3,BRCA1,MCM2,ISG15,CAND1,DERL1,MAGED2,SDHB,HGS,KPNA4,TFE3,ACLY,KPNA2,ATF6,TERF1,CDKN2A,USP13 |
| 1.048e-10 | -22.98 | LEE_LIVER_CANCER_SURVIVAL_DN | MSigDB lists | LEE_LIVER_CANCER_SURVIVAL_DN | 160 | 57 | 17377 | 2626 |
MAPRE1,MRPL42,RWDD1,AGRN,DEPDC1,SUZ12,DYNLL1,SUMO2,ACTR3,CENPF,RMI2,CDCA8,AGFG1,CCNB1,RGS2,ZADH2,BZW2,MFSD10,HDDC2,RBM17,LYAR,KIF5B,PCNA,CCNA2,EIF4A3,RPL17,SLC44A1,KNTC1,FBL,S100A6,MSH6,HMGN1,RPL35,RBX1,METTL5,GTPBP4,RPL38,SLBP,SMC2,SEPT7,MCM2,PRMT2,ANLN,ODC1,RPS9,RPSA,CBX3,NAP1L1,MTHFD2,ATAD2,NSF,CCDC6,PFDN4,HMGB2,SNRPG,YWHAH,HDAC2 |
| 1.056e-10 | -22.97 | mRNA-containing ribonucleoprotein complex export from nucleus | biological process | GO:0071427 | 104 | 43 | 17256 | 2622 |
NDC1,NUP188,CDC40,SARNP,THOC1,SRSF6,RAE1,RBM8A,ALKBH5,NUP54,AGFG1,NUP205,HNRNPA2B1,NUP210,EIF4A3,SRSF4,NUP107,UPF2,NUP153,GLE1,CHTOP,CPSF4,ZC3H3,NUP85,SEH1L,SRSF11,EIF5A,FYTTD1,NXT1,POLR2D,RNPS1,SLBP,NUP155,SRSF5,DDX39A,SYMPK,SRSF1,HHEX,UPF1,NUP62,SRSF3,NUP58,AAAS |
| 1.056e-10 | -22.97 | mRNA export from nucleus | biological process | GO:0006406 | 104 | 43 | 17256 | 2622 |
NDC1,NUP188,CDC40,SARNP,THOC1,SRSF6,RAE1,RBM8A,ALKBH5,NUP54,AGFG1,NUP205,HNRNPA2B1,NUP210,EIF4A3,SRSF4,NUP107,UPF2,NUP153,GLE1,CHTOP,CPSF4,ZC3H3,NUP85,SEH1L,SRSF11,EIF5A,FYTTD1,NXT1,POLR2D,RNPS1,SLBP,NUP155,SRSF5,DDX39A,SYMPK,SRSF1,HHEX,UPF1,NUP62,SRSF3,NUP58,AAAS |
| 1.075e-10 | -22.95 | GO_CHROMATIN_MODIFICATION | MSigDB lists | GO_CHROMATIN_MODIFICATION | 500 | 130 | 17377 | 2626 |
KDM4A,UBN1,CXXC1,SIRT2,TAF6L,CCNB1,TET3,TAF5L,SMARCE1,DNMT1,ARID4A,CARM1,RYBP,USP34,BAZ2A,TLK1,EHMT1,WDR82,AURKB,UTP3,PBRM1,USP22,USP21,ASF1B,DOT1L,PAF1,BRMS1,BRD2,CHD3,OGT,BAZ1B,ACTB,NAA60,HDAC2,HJURP,PRKAA1,CTCF,EZH1,SUPT7L,TTF1,ARID1B,CDC73,RB1,HDAC7,MBD2,ZNF335,CTR9,TNRC18,MTA2,ZMYND11,LDB1,RTF1,ARID1A,KDM3A,DAPK3,MBIP,SETD3,PRMT7,CABIN1,RUVBL2,RBBP4,CDK2,CDKN2A,SMARCD1,MBD1,ATXN3,DNMT3A,ASH1L,ARID2,SUZ12,UBR2,CHD1L,SMARCA4,CHD1,MEAF6,OIP5,SAP130,BRPF3,KDM2A,MTA1,TOP1MT,ATF2,SAP30L,SAP30,KDM3B,BRD4,KAT7,ELP4,KDM1B,MBD3,TRIM28,RBL1,ANP32E,NCOA1,BEND3,PPP5C,BRD9,EYA2,CBX4,DNAJC2,MECP2,EYA1,BABAM1,HMGN3,JMJD6,WDR5,HMG20A,IRF4,SUV39H2,HUWE1,PRDM4,NAA50,H2AFY,SS18L1,CENPM,FBL,NCOA2,NASP,KAT2A,HMGN5,RCOR1,PRMT2,PCGF1,MEN1,CBX3,ATAD2,L3MBTL3,TAF12,CENPT,DDB1 |
| 1.087e-10 | -22.94 | GSE14415_TCONV_VS_FOXP3_KO_INDUCED_TREG_UP | MSigDB lists | GSE14415_TCONV_VS_FOXP3_KO_INDUCED_TREG_UP | 156 | 56 | 17377 | 2626 |
LYRM4,NOP2,PDAP1,RBM8A,STARD7,HAUS4,PMF1,WDR5,COMMD8,GTF2F1,SSR1,ERH,PA2G4,NOL11,BANF1,RAD23B,TIMELESS,RPF2,COPS7B,AHCY,TTLL12,CPSF4,N4BP2,UBE2M,SIGMAR1,HARS,EID1,PPIE,MIER1,CIRBP,TBRG4,EXOSC9,PRPF3,MTX1,BUD13,GAR1,API5,TSR2,PDHX,MATR3,SMAP2,CAND1,ADSS,UTP20,HSPA4,PLAA,RBMX,LRPPRC,CAB39,DTD1,FKBP5,WDR76,CENPT,PDXK,GPATCH4,DDX52 |
| 1.094e-10 | -22.94 | ribosome biogenesis | biological process | GO:0042254 | 328 | 95 | 17256 | 2622 |
SART1,DDX47,RPLP2,NOP2,URB2,EBNA1BP2,EFL1,BRIX1,RPL23A,KRR1,RPL11,UTP25,RRN3,PA2G4,NOL11,EIF4A3,UTP18,NVL,ZNHIT6,EXOSC1,NOC2L,RPF2,UTP4,FTSJ3,MRM2,RPP25,RPL29,RPL35,EXOSC6,AATF,NOL8,RIOX2,RPL38,UTP3,GAR1,RPS9,LSG1,MAK16,RPSA,DDX17,RPL37,NSA2,NIP7,RPS27A,LSM6,TBL3,RPS14,RPLP1,RNASEL,RRS1,PDCD11,RPS26,NMD3,CSNK1D,RPS15,RPS2,RRP15,RPL15,GTF3A,PNO1,RRP36,KRI1,LYAR,DDX56,EXOSC7,RPL17,RPL19,DDX31,GEMIN4,FBL,MRPL11,MRM3,NSUN4,PPAN,DDX28,NOA1,WDR18,TEX10,RPL6,GTPBP4,UTP15,RPL8,RPS10,RPS24,BMS1,EXOSC9,EIF2A,RPL27A,TSR2,RPL36,UTP20,TSC1,RPL32,BYSL,DDX52 |
| 1.118e-10 | -22.91 | GO_GOLGI_VESICLE_TRANSPORT | MSigDB lists | GO_GOLGI_VESICLE_TRANSPORT | 311 | 91 | 17377 | 2626 |
CCDC93,RAB14,TMED7,CORO7,SYS1,COPA,DYNLL1,ANK3,COPE,VTI1A,TGOLN2,KIF2C,SEC16A,BCAP31,ANKRD28,NAPG,RAB8A,RAB35,TBC1D14,PPP6C,DNM2,KIF22,BCAP29,RP2,LMAN1,TFG,GCC1,DCTN1,SNX8,USO1,TMEM115,GOPC,CUL3,KIF15,MCFD2,RAB1A,ARF4,OPTN,KIF2A,SURF4,TMED10,MYO18A,DYNC1LI2,CSNK1D,KIF3B,GOLPH3L,SCAMP3,GORASP1,SCYL1,DCTN2,NKD2,CHIC2,KIF23,KLC1,RACGAP1,TMED3,ARF1,RAB6A,COPG2,COPB2,CD59,KLHL20,SEC24C,ARF5,KIFAP3,PPP6R1,MYO5A,TMED2,KDELR1,PREB,SPTAN1,GCC2,TRAPPC9,SNX2,COG1,PACS1,RAB3IP,KIF11,MACF1,GOSR1,SEC31A,GOLGA4,KIF18A,SEC23IP,GOLGA2,GOLGA7,NSF,SNAP23,STX18,PPP6R3,NRBP1 |
| 1.127e-10 | -22.91 | GSE17974_1H_VS_72H_UNTREATED_IN_VITRO_CD4_TCELL_DN | MSigDB lists | GSE17974_1H_VS_72H_UNTREATED_IN_VITRO_CD4_TCELL_DN | 177 | 61 | 17377 | 2626 |
GLT8D1,TMUB1,NUP188,UGP2,MRI1,HNRNPUL2,TMEM97,CTCF,CHCHD2,BLM,UBE2I,COMMD8,GFM2,WRB,KTN1,PARK7,MAD2L2,FBXO22,EDC3,FANCL,SEC11A,FARSA,SNRNP25,CCNA2,MTMR4,MCM5,CRAT,DUT,HADHB,CENPM,GLE1,ORC3,DRAM2,ZNF672,USO1,TRAFD1,RBX1,CCDC34,PSMG1,CDC6,VKORC1,VDAC1,SHCBP1,STYXL1,CCT8,SNRPA,CLNS1A,ASF1B,ANKZF1,KIF2A,KEAP1,PPA2,PTPN7,C4orf46,HMGB2,DTD1,WDR76,APOL2,ANXA11,IFI16,STARD3NL |
| 1.158e-10 | -22.88 | KEGG_CELL_CYCLE | MSigDB lists | KEGG_CELL_CYCLE | 124 | 48 | 17377 | 2626 |
GADD45G,PTTG1,DBF4,CUL1,ORC1,CCNB1,MAD2L2,CDKN2C,RB1,MDM2,PCNA,CCNA2,SMC3,MCM5,CDKN1B,ANAPC7,CDC25B,ORC3,PLK1,TGFB1,RBX1,PRKDC,E2F3,ANAPC2,CDC6,PKMYT1,CDC23,MCM2,SMAD2,CDC16,CDC27,RBL1,E2F4,GADD45B,TFDP1,E2F1,YWHAZ,CHEK2,TFDP2,CDK2,CCNB2,YWHAH,E2F2,SMAD4,ESPL1,HDAC2,ANAPC4,CDKN2A |
| 1.173e-10 | -22.87 | MORF_RAD54L | MSigDB lists | MORF_RAD54L | 101 | 42 | 17377 | 2626 |
IMMT,NUP188,RRM1,LANCL1,XPO7,PABPC4,HNRNPA2B1,RPA2,EIF2S2,IARS,GOT2,TXLNA,CS,TNPO3,DNMT1,NUDC,MLEC,IDH3A,PRKDC,BMS1,PKMYT1,MCFD2,MCM2,DDX39A,CDK11A,ABCF1,TARS,POLR2A,CHAF1A,ALG3,EPRS,SAFB,TFDP1,LRPPRC,KHSRP,BAZ1B,NUP62,TCOF1,RUVBL2,SCARB1,HDAC2,SSRP1 |
| 1.181e-10 | -22.86 | CHEMNITZ_RESPONSE_TO_PROSTAGLANDIN_E2_UP | MSigDB lists | CHEMNITZ_RESPONSE_TO_PROSTAGLANDIN_E2_UP | 128 | 49 | 17377 | 2626 |
PWWP2A,SKA3,HJURP,CHD1L,PTTG1,CENPF,TPX2,PTP4A3,CCNB1,NCAPG,C19orf48,SPAG5,FANCL,MZT2A,NUP210,IMPAD1,PRC1,GTSE1,RNASEH2A,C8orf59,SMC4,ERCC1,TK1,ASPM,MKI67,RPL8,RRM2,NUSAP1,CDC6,PCGF1,TRIM28,RPS9,SNRPA,ASF1B,CHAF1A,GEMIN5,BOLA3,MTHFD2,ATAD2,UAP1,BIRC5,SLC16A1,WDR76,ATP6V1C1,CHMP7,UBE2C,CCNB2,MZT2B,AP2S1 |
| 1.194e-10 | -22.85 | GSE22611_NOD2_TRANSDUCED_VS_CTRL_HEK293T_STIMULATED_WITH_MDP_2H_DN | MSigDB lists | GSE22611_NOD2_TRANSDUCED_VS_CTRL_HEK293T_STIMULATED_WITH_MDP_2H_DN | 173 | 60 | 17377 | 2626 |
SLC12A7,SRM,PKP4,EWSR1,NUP188,RRP15,MDH2,SLC2A1,ALKBH5,COX4I1,SLC29A1,ADPGK,SND1,SNRPD3,PCBP1,RPN1,SLC1A4,SIVA1,AHSA1,RPF2,TAF5L,KNTC1,POLR1B,MRPL21,RNF26,PDIA6,DNMT1,TMEM14C,IMPA2,ABCC1,HEMK1,GUK1,PGS1,RDH10,LDHA,CDC6,MCM2,ODC1,ERC1,RPSA,AKAP1,GEMIN5,SDHB,NUCB1,MTHFD2,POLE,DGCR8,TFDP1,LPCAT4,E2F1,COX5A,SCARB1,PPP5C,USP53,LRP8,PFKP,GPATCH4,IPO4,SSSCA1,EGLN1 |
| 1.196e-10 | -22.85 | GSE15930_NAIVE_VS_24H_IN_VITRO_STIM_INFAB_CD8_TCELL_DN | MSigDB lists | GSE15930_NAIVE_VS_24H_IN_VITRO_STIM_INFAB_CD8_TCELL_DN | 190 | 64 | 17377 | 2626 |
SRM,GALK1,GCLM,NOP2,CHERP,PDAP1,MOGS,OLA1,TMEM97,RRM1,KIF23,JMJD6,HAUS4,POMP,INO80E,FKBP2,SPR,POLR3K,IRF4,DECR1,RPN1,CLIC4,NVL,MCM5,SIVA1,PDS5B,PDCD2,RPF2,ALDH18A1,DNMT1,MTX2,HDHD2,PPA1,NUP85,TACC3,CARM1,FDFT1,ELOF1,METTL1,PRIM2,POLR2L,TSPAN31,RAD51AP1,MKI67,MRPS10,BRCA1,MCM2,ANLN,RHOT1,RFC2,SLC19A1,MRPL2,TPD52L2,CDKN2AIPNL,MTHFD2,BIRC5,DCK,LUC7L3,CRCP,NDUFS5,RBPJ,PGAM1,HRAS,GCSH |
| 1.205e-10 | -22.84 | PRPF3 (pre-mRNA processing factor 3) | protein interactions | 9129 | 128 | 51 | 17029 | 2761 |
SART1,XAB2,SF3B1,OLA1,USP39,CHCHD2,CDK13,THRAP3,SNRPD3,PCBP1,SF3B2,GTPBP3,CTNNBL1,EIF4A3,KIFAP3,TARDBP,FBL,PABPC1,ILKAP,DVL2,HNRNPM,PRPF19,CDC5L,SNRNP200,ZCCHC10,RBM42,SNRPB,RPS10,RNPS1,LSM8,KRAS,AURKB,PRPF3,BRCA1,SRSF5,SEPT7,TXNL4A,PATL1,SF3A2,DDX23,SUPT16H,UTP20,RBM25,RPL32,LSM6,MFAP1,PRPF4,SNRPG,FAU,SNRNP70,SMNDC1 |
| 1.215e-10 | -22.83 | MORI_IMMATURE_B_LYMPHOCYTE_DN | MSigDB lists | MORI_IMMATURE_B_LYMPHOCYTE_DN | 90 | 39 | 17377 | 2626 |
TXN,MCM10,HNRNPAB,UCK2,CDCA3,RRM1,SMARCA4,SLC29A1,CCNB1,STMN1,DTL,CDKN2C,PCNA,CCNA2,DUT,PRC1,DNMT1,SMC4,MKI67,SLBP,RRM2,NUSAP1,SMC2,MCM2,H2AFV,PRIM1,HMGN2,MTHFD2,DCK,CDCA5,H2AFX,SLC16A1,ANP32E,KPNA2,HMGB2,RBBP4,CCNB2,UBE2C,TUBB |
| 1.225e-10 | -22.82 | FBXW11 (F-box and WD repeat domain containing 11) | protein interactions | 23291 | 404 | 116 | 17029 | 2761 |
NOP9,MAX,GGNBP2,HNRNPAB,TRAF7,SF3B1,SUZ12,PPP1R15B,EIF3D,HNRNPUL2,YTHDC2,WDTC1,CUL1,PRKACA,CHD1,APP,MRPL19,PABPC4,SF3B2,EEF2K,CDK5,HNRNPA2B1,SPINDOC,MDM2,NOL11,ZKSCAN1,LPIN2,AKAP8,MRPS27,CRY2,NUP153,MAST2,CDC25B,RNASEH2A,MRPL57,PDCL3,AATF,RBX1,BTG2,HNRNPF,WBP1,TANC1,PRPSAP1,EML4,RPSA,SUPT16H,GEMIN5,DAP3,EIF4ENIF1,WDR11,HNRNPR,AXIN1,OGT,KPNA2,TRIM32,FUS,MRPL13,LONP2,PDCD4,UBE2D3,GALK1,CLSPN,HJURP,RAE1,NACA,DHX9,THRAP3,ATP5F1B,PRPF39,CNOT11,FBXO5,TFAP4,HERC3,HUWE1,RTCB,ZNF326,AXIN2,FOXN2,YBX1,ZRANB1,MCPH1,PABPC1,NUDC,RPAP3,YTHDC1,PRRC2A,TACC1,DENND4C,DCAF8,RPS10,ILF3,UBE4B,BORA,CCT8,MATR3,TWISTNB,ZFR,PSMC4,PFDN5,EPRS,KEAP1,UPF1,SYNCRIP,POLE,PFDN4,TATDN2,RBMX,HNRNPH3,LRPPRC,YWHAZ,DUSP11,WDR62,HNRNPDL,MZT2B,IFI16,FAF1 |
| 1.238e-10 | -22.81 | HNRNPD (heterogeneous nuclear ribonucleoprotein D) | protein interactions | 3184 | 279 | 88 | 17029 | 2761 |
IMMT,CYLD,HNRNPAB,IVNS1ABP,ABCC10,RBM8A,CUL1,C2orf49,UBE2I,PRKACA,PCBP1,MYEF2,RBM4,SNAPC4,PAIP1,CSDE1,HNRNPA2B1,MDM2,DNM2,PCBP2,SRSF10,PPP1R18,SEPT9,VHL,MRPL12,HNRNPF,CUL3,SREK1,BRCA1,MCM2,RPSA,ARF4,MAP3K4,EIF3K,AHNAK,HSPA4,MRPL55,HNRNPR,PDRG1,SAFB,H2AFX,ACTB,FUS,COPS6,USP11,ARRB2,SMURF1,C2CD5,CAPN1,EWSR1,SRSF6,CUTA,PCSK7,RPA2,KLF16,INTS7,BANF1,MSH2,NAA50,GTSE1,YBX1,BCL2,PABPC1,STAU1,GUK1,MTA2,LDHA,UHRF1BP1,PNPLA8,PKM,PICALM,TARS,RPA1,CAND1,GOLGA4,SYNCRIP,UAP1,PRDX3,RBMX,HNRNPH3,MAPK6,KHSRP,CDK2,ECPAS,HNRNPDL,CD81,HEXA,ESPL1 |
| 1.244e-10 | -22.81 | CRY2 (cryptochrome circadian regulator 2) | protein interactions | 1408 | 151 | 57 | 17029 | 2761 |
SRM,USP7,RPS2,COPA,CUL1,SEC16A,PCBP1,SDHA,LMNA,CRKL,RPN1,PSMD2,PSMD1,IARS,HUWE1,MCM5,EFTUD2,AKAP8,TIMELESS,CRY2,ANAPC7,HNRNPM,SMC4,CCT2,SNRNP200,PRKDC,TUFM,ATXN1,DDX20,BRCA1,SMC2,CCT8,MATR3,DHX15,PSMC4,DDX17,CAND1,GEMIN5,EPRS,KPNA1,ATP1A1,RPS14,PSMD3,MAP4,ARNTL,ACLY,LRPPRC,KHSRP,STK11,RUVBL2,FBXL3,PPP5C,USP11,HNRNPDL,PPP2R2D,DDB1,CSNK1D |
| 1.266e-10 | -22.79 | SRSF5 (serine and arginine rich splicing factor 5) | protein interactions | 6430 | 117 | 48 | 17029 | 2761 |
SART1,RPS2,CYLD,EWSR1,SUZ12,SF3B1,RPS6KA1,SRSF6,EIF3D,MYH9,CUL1,USP39,SDF2L1,PPP3CB,IKBIP,MAPK14,LMNA,HNRNPA2B1,EIF4A3,HUWE1,MSH2,TRA2B,HNRNPM,TIMM50,CDC5L,PRPF19,SRPK2,SF3B6,SMU1,CUL3,ILF3,SREK1,PRPF3,SEPT7,RHOT2,SF3A2,DHX15,SRSF1,CAND1,SURF4,HNRNPR,MAPK6,PSAP,SRSF3,RRS1,ATP6V1C1,SMURF1,HIPK3 |
| 1.285e-10 | -22.78 | cellular process | biological process | GO:0009987 | 15185 | 2401 | 17256 | 2622 |
ZBTB10,HEXB,TGOLN2,CCNL2,FBXO22,EEF2K,RAD23B,ATP13A3,DNM2,ZNRD1,FTSJ3,USP34,ERCC1,NRAS,EHMT1,KIF15,HNRNPF,WDHD1,MIER2,DIDO1,MCM2,RAB22A,MID1IP1,SMAD2,RPS27A,MYO18A,OGT,MPV17,COX5A,KLHL42,SMAD1,ZNF75A,ANXA11,SLC25A33,ZNF720,GGA1,SEC61G,MUM1,TRIO,RAB23,KCTD17,HAUS4,EIF2AK4,APH1B,PARN,CDC73,MYL6B,ATG4A,TMEM179B,PDXP,SMC3,TNPO3,GEMIN4,MVP,NUP85,PABPC1,NSUN4,PPP6R1,PPA1,IFRD1,AGGF1,FOXK1,GTPBP4,MAP7D1,MRPL16,ELK1,EIF4H,RDH11,MAGED2,KPNA1,ETS2,TYW5,WIPI2,RUFY3,PDLIM5,ACSF2,EXOC3,RHOG,C5orf30,VTI1A,STARD7,SLC35B2,INO80E,RCOR3,LCLAT1,CPNE3,RBM23,AHCTF1,ZNF420,GMEB1,NSFL1C,SEPT11,ZNF226,GPD1L,ZC3H3,PDCL3,SNX8,EID1,IDH3A,POLR2D,HTATIP2,MEF2D,TANC1,MAT2A,VPS26B,CORO1C,NSMCE2,CAMKMT,PPP5C,PITRM1,TUBB,COMMD10,ZNF445,SRSF6,CCM2,HABP4,FLOT1,BTN3A1,ABHD14B,ATG2B,ATP5F1B,NEXMIF,TUT4,PPP1R3B,GOLM1,ZBTB45,HUWE1,ZNF260,NAA50,ANXA5,LTN1,KANSL2,UBE3B,NAP1L4,ST8SIA2,ZNF710,RPL22L1,MED22,SPTAN1,STAU1,DDX24,TCTEX1D2,TACC1,USP42,MRS2,LDHA,HEBP2,LLPH,RAB3IP,PICALM,SH3BP5,SLC19A1,ACOX1,PARG,FAM3C,AEN,PARP10,YWHAH,WDR45B,THAP5,FAM129A,TRIM11,YTHDC2,RBM8A,SNX15,ENSA,SND1,RUFY1,ZER1,PRNP,KRR1,RAB8A,NUP210,NT5DC1,NOC2L,EIF5,TACC3,RYBP,PTPN18,MIOS,SNRPB,CDC6,PBRM1,UTP3,ODC1,USP21,TRAM2,GRIPAP1,BCL7C,ARRDC1,ADAM9,DVL1,NUMB,ZNF564,FUBP1,CTU2,ZCCHC9,CENPF,LAMTOR3,CHCHD2,NCKAP1,RSAD1,TNS3,SUB1,MBD2,SSBP3,KIF13B,XPA,AHCY,RBM3,MRPL48,LRSAM1,HDHD2,NTPCR,NSDHL,AMD1,CAMSAP1,ZNF761,ICAM2,METTL22,STYXL1,APPL1,BBS12,RXRB,SDHB,PCM1,GALNT2,NLRC5,RUVBL2,MYO9A,CCNB2,ECPAS,USP7,RPLP2,SUCLG1,ARID2,TMX4,SLC2A1,ATP6V1B2,LYN,PCBP1,BCAP31,MRPL50,VAV1,PSMA6,ZNF473,KMT5C,BRPF3,ZNF302,TARDBP,BCAP29,SPIDR,CTDSP2,PRPF19,PPIF,KDM3B,MND1,CLCN3,BIRC3,RAB7A,PPIE,CHMP2B,VDAC1,TMEM201,EIF3H,IDE,DHX16,UHRF2,CHMP4B,XRCC3,PARD3,BCL2L12,NIFK,MCM10,MTERF1,KLHL21,PDAP1,TMX3,CDCA8,GTF3A,ARF1,SLC12A9,CDK11B,PAGR1,TUBGCP2,DNAJB9,HOMER1,POLR1B,RNF5,RBM15B,PPAN,RHOA,RPRD1A,TOP3A,ARHGEF12,PCGF1,DDX23,RAB18,CACNB1,TRIM26,PDCD6,NEK1,ATP6V1D,L3MBTL3,NEIL3,CTBS,BBX,IMPDH1,TAF12,NR2F2,PGAM1,ARHGAP23,HIPK3,IFI16,TXN,NUP188,H2AFZ,TMEM203,PRKCSH,USP39,UBE2I,PARK7,GLMP,ASPHD2,RAB4A,TRA2B,SUCLG2,TAF5L,CISD2,SMARCE1,ZNF800,CDC5L,ZNF524,SGCE,OSBP2,NSUN2,USP22,CLNS1A,EIF3A,ZMYM3,DOT1L,IWS1,MKNK1,WAS,KIF18B,TPP2,ZMAT3,B4GALT2,PRPF38B,RECQL,EWSR1,GADD45G,RRM1,DNAAF5,B4GALT1,CYCS,SUPT7L,ZNF518A,TMEM165,WDR48,SPAG5,CNOT3,NPLOC4,RTKN,TMEM250,EXOSC7,KLHL5,LRRC8D,PPP4R1,MSH2,PIGG,OSTF1,FBXL7,MRPL40,TNRC18,SYTL3,APOL1,EIF5A,GCC2,PRIM2,ELL2,COQ8A,RDH10,USF3,MFNG,RPS24,GORASP2,CAPZA2,ADRB2,MTR,CCT8,PHF6,PFDN5,GOLGA2,EPOP,RBMX,MED15,PIAS2,APPL2,SAMD8,CDKN2A,NUDT3,ZNF511,NDC1,ATXN3,RAF1,C2orf49,CD320,CCNA2,MTMR4,BRI3,TAP2,AQR,TP53BP2,CDK12,ILKAP,SAP30,BRD4,DRAP1,LRRC8A,ELP4,PKMYT1,ASB13,SERP1,TRIM28,SUPT16H,EIF3K,CHMP4A,CERS6,ATF6,XRCC4,ADAM23,PRPF4B,NDUFS1,DEPDC1,MECP2,SECISBP2,SPDL1,HMG20A,WWP2,SLC25A36,CCNK,DNAJC8,ELP5,AXIN2,CARF,CITED2,KAT2A,TMEM126B,RABIF,ADSL,BMS1,KCNQ1,OTUD3,ARSK,MACF1,KLF6,COMMD4,KIF11,FADD,SH3GLB1,MYO1F,CBX3,SELENOW,INF2,TMEM127,PPP1R11,DUSP11,DDX5,WDR62,TAF6,ESPL1,PURA,FAM83G,IPO4,DDB1,CCNC,PIGM,GPR132,PTP4A3,UBE2Q1,BRIX1,MRPL19,ZNF696,SF3B2,PCYOX1L,CDC42,SYNM,GOT2,JAZF1,HADHB,RPF2,SLC35C2,CARM1,SRPK2,WDR41,LARS,RIOX2,TMEM216,SUMF2,KMT2C,OGFR,PRPSAP1,MPC1,ASF1B,RPL37,MAN2A2,EIF4ENIF1,NIP7,U2SURP,MIA2,ZNF268,VPS4A,ATP6V0E1,PPP1R2,PM20D2,RGS2,LYAR,EI24,FAM89B,POLR2I,SUGP2,GBA,SYVN1,EIF2A,CCDC71L,DAPK3,ARHGAP15,MASTL,UAP1,NFIL3,FN3KRP,YWHAZ,CTSA,TMEM14A,TOB1,TSEN15,ADNP2,TCF12,PRKAB1,MDH2,SMARCA4,ORC1,RRN3,UBXN2A,IARS,CD3EAP,KIF14,EXOSC1,CS,CLTB,DNAL4,CSTF1,CHP1,POU2AF1,UBQLN4,HPDL,PGGT1B,SELPLG,SMU1,LSM8,ATXN1,GLO1,BICD2,OGDH,CADM1,EDEM2,TOLLIP,FANCE,MBD3,RPS9,PDHX,DUS3L,SURF4,ARNTL,ANP32E,FKBP5,TMEM101,PDCD2L,ABCA1,CWC25,GCLM,ZNF316,RAE1,DCTN2,NUP54,PAWR,MXD4,DCUN1D4,PIP4K2A,XPR1,FERMT3,KIF5B,KLHL20,SEC24C,RRBP1,DUS2,ARHGEF2,ANP32A,STAT3,MYO5A,AMPD2,TXNL1,COA3,DCAF6,FAM49B,ATP2C1,RFFL,COG1,RCOR1,PRMT2,TFEB,LEMD2,CTSL,UPF1,ELMO1,ZC3H7B,DTX4,ZMIZ1,HRAS,TERF1,SLF2,TMED7,FGFR1OP,MAP3K7CL,PIGQ,AGPAT1,CNTROB,PPP1R16B,MIEN1,EDRF1,MIS12,CIPC,GSDMB,PDS5B,NUP153,SENP1,PGAP2,TMEM115,AATF,DCUN1D5,PLEKHF2,BRMS1,AXIN1,SMG9,LONP2,NDUFV2,PHF23,CERK,SLC4A2,EZH1,ITGB5,LMNA,MCTS1,DDX56,EIF2S2,FOXN2,CARS2,RB1CC1,PRRC2A,ZMYND11,PGS1,MYBL2,ARMT1,SRSF5,MPG,CYB5A,NCDN,POLR2J,SETD3,TEX30,PTAR1,CNOT6,NDE1,PLPP6,EGLN1,ZNF207,ANKRD27,ABCA3,SARNP,IVNS1ABP,RMI2,NUF2,RXYLT1,NIT2,ZNF267,EFL1,TCF19,KTN1,APP,CLUAP1,PRKD3,ATP2A2,UTP18,GRSF1,DUT,ANAPC7,RNF19A,CLN6,RNF169,ATP6V1G1,ADCY7,ENPP4,RNPS1,CDCA2,FKBP3,DDX17,CHCHD3,PEX5,CDC16,HIPK2,NT5C3B,MBOAT1,TICAM1,PDXK,ZBTB11,TMBIM4,ANXA6,GMCL1,UBE4A,ETS1,IL21R,WRB,PLPP5,PNO1,ZNF92,CAPN2,ADD3,SUV39H2,TTLL12,TPCN1,TMX1,HNRNPM,LYPLA2,LDHB,PPP3CA,POLK,JTB,EMP3,MTMR12,ZP3,PDE3B,KIF18A,CCDC6,WNT5B,MAPK6,LY75,SLC25A19,RGL1,PSAP,WDR76,IGBP1,FAF1,SNAPIN,COX15,AGRN,THOC1,GPBP1L1,GNPDA1,PPP1R15B,CSNK2A1,EBNA1BP2,BIRC2,ATPAF1,ABL2,DLG5,XRCC2,ZFYVE27,MCMBP,PTPRK,CDC37,METTL1,SP3,EXOSC6,HARS,GMFB,CYSTM1,ESYT1,ANLN,RAB5B,RHEB,DPYSL3,TBC1D17,TIMM13,TONSL,NAGLU,ACTB,ZNF45,C2CD5,TMUB1,CTCF,ASAH1,DOCK11,ASXL2,CRLF3,NUS1,CMTR2,SLC27A4,MDFIC,MAML1,CYTH1,NQO2,UTP15,EIF2AK1,EIF4G2,ZDHHC3,CDC27,SNAP23,TBPL1,PRMT7,ATP5F1A,KCTD7,NDUFA5,CYLD,UGP2,DYNLL1,ZADH2,GGPS1,RPAIN,RAD23A,SEC11A,PDK2,ATP6V0B,ZBTB21,STRBP,TNFAIP8,DUS4L,MRPL34,PDCD2,SAP30L,CLPTM1,RPL29,TIMP2,RPL35,BTG2,TUBGCP5,FRAT2,MTMR6,NFATC2,KDM1B,USP36,MRPL2,ATP1A1,CLK3,MAFK,PSMD3,NDUFA11,CEP55,ZNF436,DNAJC17,NCOA1,SLC25A39,ZC3HC1,CDC40,RRP15,DAP,GNE,SMC6,ARFIP2,NKRF,CHAC2,BZW2,WRNIP1,SS18L1,CENPM,PTGES3,CAMK2G,MLEC,ZNF202,PPWD1,RHOT2,NEU1,GOLGA7,TWSG1,PGRMC1,GLG1,FAM126A,SPCS3,RPS6KC1,UBE2C,PPCS,NDUFB6,ZDHHC8,PLXNA1,CCNB1,COMMD6,SLC20A1,POLR3K,UTP25,SNUPN,TFG,PLCL2,SPTSSA,SEH1L,ATG9A,PBK,ARHGAP45,MKI67,DDX20,GALNT7,AMDHD2,CCNF,FOXRED1,RBM47,PTER,WDR4,DHTKD1,TRAF5,HDAC2,HSPH1,MAPRE1,LIME1,CHTF18,ADO,KIF23,PMF1,NOTCH2,COPG2,JMY,NDUFAF6,FKBP1A,SLC31A1,SNX18,ATIC,CTPS1,ATP6V0A2,RNF135,PIKFYVE,LPCAT1,EEF1D,TMED2,FTL,PHF10,DDX28,ZNF84,SIGMAR1,PIP4K2C,PLEC,RIT1,CYFIP2,KDM3A,SF3A2,FAS,EPRS,ZNF777,CSNK1G1,QARS,DCAF11,PPP3R1,TCOF1,NRBP1,CABLES1,DNMT3A,CKLF,RWDD1,TRIP10,RPS6KA1,SF3B1,SUZ12,GPR89A,RAC1,OLA1,GNB2,SDE2,FLAD1,APLP2,KDM2A,CDKN1B,TALDO1,GPX4,ATP13A1,RFC3,MAPRE2,ERF,TAOK1,CUL3,SLBP,KIAA1586,POLG2,PSMB9,H2AFV,GAR1,DHX57,CENPU,SOCS7,NSA2,HSPA4,JAK1,MRPL55,TBL3,FAAP100,GOLGA8A,H2AFX,SEL1L,B4GALT3,PDCD11,CSNK1D,ATMIN,POLQ,POU3F2,OTUD5,NCOR2,PKP4,TWNK,BABAM1,CDCA3,SLC25A12,BLM,GTF2F1,RPL17,CRAT,PRC1,UPF2,COPS7B,CNOT6L,CNPY3,IFT46,UBE2M,TSHZ1,ZFP64,STRIP1,DENND1B,DENND4C,TRIR,WDR18,ILF3,RPL8,LRRC1,RHOT1,MARK2,TSR2,ECH1,PRDX1,POLR2A,FBXO21,NUCB1,GNA12,PFDN4,PRDX3,HNRNPH3,STX18,TFDP1,NAXE,KHSRP,ASNA1,CPEB2,SSSCA1,BYSL,VPS29,DDX52,MIB2,ADA2,PTMS,IER2,NOP2,UBN1,NF1,DCAF15,ALKBH5,MOGS,UBE2Z,TAF6L,MAPK14,BECN1,SNAPC4,RNF103,BCAT2,MBD4,CYREN,C18orf32,METTL14,ZNHIT6,IMPAD1,RCSD1,PHTF1,SRI,KHDC4,KIF22,ZBTB22,NFU1,OGG1,ELOF1,COPS8,TRIM8,RRM2,SOX4,ABHD5,PAF1,UBTF,CXXC4,SPATA2,UEVLD,ATXN2L,PQBP1,IARS2,GALNT10,ROCK1,STARD3NL,RPS15,PIGN,AGTRAP,CDIP1,CIB1,SRRT,APOPT1,ZNF449,CAPZA1,KIFAP3,BCL2,GLTP,N4BP2,HP1BP3,VOPP1,ISG15,CAND1,GNAS,TSC1,RBM25,CDCA5,ZFP90,RBBP4,NANP,NIPSNAP2,HNRNPDL,ZBTB24,SMARCD1,WASF2,MBD1,MMACHC,TOMM20,FAM92A,IFI27L1,MPHOSPH8,GNPNAT1,NSD3,CHD1,MEAF6,MIEF1,BABAM2,AKAP8,RPN2,CHTOP,F2R,ABI1,SCYL3,TMEM14C,HTRA2,RLIM,MOSPD1,FAM172A,ZNF500,PSMB7,NLN,WIPF1,ERBIN,NDUFB1,BUD13,PEF1,EIF3G,BTBD1,TAB2,TULP3,CHCHD1,WDR59,CANT1,SCARB1,GAS2,USP11,SMURF1,PPP2R2D,TSPAN5,CDS2,MAGEH1,MRPL42,EYA1,MRPS26,LETMD1,KLF13,HDDC2,RGS1,MAN1A1,FBXO5,GART,PELO,TANK,BRD7,MRPL11,SAMD4B,ZDHHC18,GTF3C6,POLR3GL,WDR81,MEN1,ZNF407,MFN2,COX8A,ZRANB2,SRSF3,MBD6,ATP6V1C1,TATDN1,IDH3B,TSC2,LACTB2,CMTM6,RBM4,ZNF275,RPL23A,CDKN2C,NAPG,USF1,DNAAF2,MECR,AP1M1,UPRT,CRY2,ECD,MOB1A,RNF26,TIPARP,ANKRD9,MGAT5,MRPL57,BAK1,RHOBTB3,ZNF559,GABPA,ARF4,GINS4,KRIT1,AHNAK,RAD18,PDRG1,RNASEL,CHPF2,OAZ1,SMNDC1,PDCD4,HIVEP3,CLSPN,RHOC,DHX9,PDCD7,PSMD9,HAUS2,CD59,TFAP4,RNFT1,MEGF8,RIMS3,FBXO7,EFTUD2,MYDGF,CPSF4,MRPL21,PHKG2,LUC7L2,SRSF11,EIF3L,MAPKAPK3,MTA2,MTFR2,SF3B6,TYW1,ERO1A,ITM2A,USP10,BCLAF1,MTX1,FNTA,TXNDC16,CFAP20,ZNF830,MRPL3,NUP58,ALS2,KARS,TRIM41,GGNBP2,NQO1,POC1A,ANK3,PTTG1,TPX2,GLRX3,STMN1,REPS1,ABHD16A,FBXL6,SH3BP1,MTA1,UBA5,CLCN6,NABP1,INTS12,MICU2,RPRD1B,CGGBP1,CPNE1,ULK3,SEC61B,POLR2L,FAM118B,GOPC,KAT7,CIRBP,E2F3,RPL38,CRNKL1,PFKFB3,GORAB,RAB1A,GIGYF1,KIF2A,PPP2CA,ALDH3B1,LSM6,RNF38,SNRPG,DMWD,USP13,MZT1,ZFP91,TRMT6,IP6K2,WDR5,IFT27,PMVK,NEIL2,SAPCD2,RRP36,SRXN1,RPA2,PSMD2,PDCD10,CLIC4,COQ4,ITGB8,ARHGEF1,GTF2H2,FBXL19,UTP20,MAGT1,GPS2,DBI,SSNA1,CD81,FANCI,PAPOLA,CREM,TET3,FANCL,GLIS2,TIMM23,IL6ST,INTS1,POP7,SLC44A1,MTPN,ASB6,PLK1,RPP25,CELSR2,SEPT9,RBX1,APH1A,RAD51AP1,PSMG1,UBE2V1,EAF2,IL12RB1,KRTCAP2,LUC7L,ALG3,TRIM4,AGPAT2,CHD3,E2F4,ZNF367,KPNA2,PRPF4,BEND6,CLN3,FAM208A,NGLY1,POT1,RMND5A,HJURP,PHB2,DNAJB2,NKD2,SDC2,KLC1,COX4I1,CDK13,ADCK5,DNAJB1,RAB6A,CNOT11,ARID1B,C1GALT1,MLX,UBE2Q2,CCP110,ZNF746,ARL6IP1,CTR9,ICE2,ABHD2,DCAF8,ACSL3,LDB1,MAP4K3,ARMC8,RBM38,RMC1,IRF5,NMT2,RPL36,HAUS8,PAXX,MBIP,ORMDL2,COX7A2L,LAMTOR4,ZDHHC7,SIL1,DTD1,UNC13C,BCCIP,SART1,TRAF7,NDUFAF2,TOR1AIP1,ZNF416,LAGE3,ZFYVE21,RRAGC,ZNF121,OIP5,NRF1,ABRAXAS2,PPME1,PIN1,RPAP1,CABLES2,AHCYL1,TOP1MT,LMAN1,STRAP,SPSB3,ZNF583,SNX25,ARHGAP17,POLR2G,ZNF780B,PPT1,NUP155,DCLRE1C,MRPS14,SUGP1,AFDN,RBL1,UBXN2B,STK38,FASTK,H3F3A,CHID1,SMAD4,RAD51D,SLC30A9,UNK,CMAS,NADSYN1,AGO2,HMGN3,NCAPG,SCYL2,FZD6,GTPBP3,HERC3,CTSS,ORC3,RNLS,YTHDC1,ACP2,HMGN5,CSRP1,PRKDC,TUFM,RANGAP1,PNPLA8,HAGH,API5,SEC23IP,E2F1,TMEM219,USP20,RBPJ,PDCD6IP,MAX,GXYLT1,ADAM10,CXXC1,AP3M2,CUL1,NANS,GYG1,OAT,MYEF2,MTFR1L,PA2G4,NOL11,FIZ1,ZNF200,AP2B1,FBXW2,MARCH2,SLC26A2,SRSF10,KLF10,SUPT20H,CBFB,RFC2,RAB2B,PRIM1,MAP3K4,HHEX,BRD2,LUC7L3,RPS14,MAP4,MRPL27,BTF3,PTPDC1,SLF1,CCDC59,PTOV1,COX5B,DNAJC5,DHPS,POLR2K,VAV2,PRKAA1,GSPT2,TATDN3,PXMP2,PRPF39,PSEN1,ZNF79,PDXDC1,VPS25,NDUFS7,YY1AP1,RPN1,LHX8,ARPC5,ZNRF2,TPST1,DAPK1,CYC1,MRM3,FDFT1,SOCS5,PIGT,CPQ,WDR1,ZNF574,C1orf35,EXOSC9,ARID1A,FXR1,GOSR1,MAP2K2,TWISTNB,XRCC5,PI4K2A,DERL1,CAT,SEC31A,MTHFD2,HSPBP1,CEBPG,ARAP1,FAM83D,USP32,CABIN1,SMPD4,GPI,TP53RK,REPS2,RAB11B,UROD,SLC39A13,POMP,BCL2L1,SPINDOC,NUDT19,DECR1,SIAH1,RALB,LPIN2,ADCY9,MRPS27,SOCS6,TTC3,RNASEH2A,CFL1,ANKLE2,CDC123,VDAC2,EDF1,EML4,ERC1,ANKZF1,RAD51C,ZNF282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|
| 1.293e-10 | -22.77 | RNA biosynthetic process | biological process | GO:0032774 | 2611 | 507 | 17256 | 2622 |
ZBTB10,TXN,ZNF496,MAX,KDM4A,CXXC1,CCNL2,CCNB1,COMMD6,EDRF1,POLR3K,MYEF2,ZNF275,PA2G4,USF1,CIPC,NOL11,FIZ1,SRSF4,ZNF200,CRY2,TAF5L,ECD,ZNRD1,DNMT1,ZNF800,CDC5L,ZNF524,ZNF672,ZNF559,KLF10,GABPA,ELOA,MIER2,TOPORS,USP22,DIDO1,CBFB,PRIM1,IWS1,BRMS1,HHEX,SMAD2,BRD2,ZNF689,VIPAS39,BTF3,TFDP2,SMAD1,ARRB2,E2F2,ZNF75A,CCDC59,HDAC2,SLC25A33,PTOV1,SSRP1,HIVEP3,EWSR1,POLR2K,PRKAA1,DHX9,EZH1,PMF1,NOTCH2,SUPT7L,ZNF79,ZNF518A,VPS25,CDC73,YY1AP1,CNOT3,MCTS1,TFAP4,LHX8,INTS7,KLF16,HDAC7,ZNF326,FOXN2,CPSF4,EEF1D,SRSF11,PHF10,ZNF84,ETV3,PRIM2,FOXK1,ELL2,RB1CC1,ZMYND11,ZNF574,MYBL2,BCLAF1,ARID1A,SRSF5,CBFA2T2,ELK1,KDM3A,PHF6,TWISTNB,XRCC5,ZNF777,SERTAD2,POLR2J,ETS2,ZFP92,SETD3,RBMX,MED15,PIAS2,CEBPG,CNOT6,YY1,RNF14,NRBP1,SGF29,ZNF511,ZNF296,SARNP,ATXN3,TRERF1,IVNS1ABP,ZBTB37,SUZ12,PTTG1,CREBL2,ZNF267,INO80E,SAFB2,RCOR3,TCF19,TERF2IP,SPINDOC,ZNF420,ZNF75D,SP100,KDM2A,ZKSCAN1,MTA1,UCHL5,GMEB1,LPIN2,NABP1,INTS12,ZNF226,ATF2,RPRD1B,CDK12,CGGBP1,SAP30,CPNE1,BRD4,POLR2L,EID1,ERF,KAT7,DRAP1,INTS13,WBP2,POLR2D,RNPS1,E2F3,SLBP,ELP4,EDF1,MEF2D,TRIM28,CENPU,PRDM11,SUPT16H,DDX17,TAF2,CHCHD3,VEZF1,ZNF282,HINT1,SAFB,HIPK2,STAT1,ATF6,SNRPG,BEND3,PPP5C,ZBTB11,EYA2,ATMIN,POU3F2,COMMD10,NCOR2,ZNF786,ZNF445,DEPDC1,SRSF6,MECP2,TWNK,TCF3,HABP4,JMJD6,ARGLU1,MYNN,WDR5,ETS1,HMG20A,FOXO3,MAD2L2,NEXMIF,ZNF92,WWP2,GTF2F1,CCNK,ZBTB45,SUV39H2,ELP5,PPP1R8,ZNF260,PRDM4,CARF,CITED2,CNOT6L,ZNF710,CREB1,GTF2H2,MED22,NCOA2,TSHZ1,PDPK1,ZFP64,KAT2A,ZNF512,RFXANK,ILF3,DDX39A,COMMD4,KLF6,POLR2A,CBX3,ZNF862,ZNF180,KEAP1,ZHX1,PITX1,TFDP1,LRPPRC,PML,KHSRP,DDX5,HMGB2,USF2,TAF6,PURA,THAP5,RORB,CCNC,ZNF76,IER2,THOC1,GPBP1L1,KMT2E,PHRF1,RBM8A,CSNK2A1,ZNF107,TAF6L,SND1,SIRT2,SNRPD3,COMMD5,MAPK14,SNAPC4,BIRC2,ZNF696,PAPOLA,CREM,LIN9,GLIS2,EIF4A3,ZNF639,INTS1,JAZF1,ETV6,PHTF1,NOC2L,ZBTB22,TCEA1,MYBL1,ARID4A,CARM1,CCAR1,RYBP,ELOF1,SP3,DEAF1,BAZ2A,SNRPB,RIOX2,MRPL12,PBRM1,BRCA1,EAF2,KMT2C,SOX4,USP21,ASF1B,PAF1,UBTF,BRWD1,CHD3,E2F4,ZNF367,PQBP1,CRCP,BAZ1B,ZNF268,CHEK2,DVL1,ZNF45,BEND6,FAM208A,ZNF564,FUBP1,ZCCHC9,PHB2,ZNF768,NACA,CTCF,CHCHD2,MED13L,MEF2A,CDK13,THRAP3,RLF,ASXL2,CNOT11,TTF1,SRRT,ARID1B,LYAR,SUB1,RB1,MLX,NFATC3,MED8,ZNF449,MED10,MBD2,SSBP3,ZNF746,ZNF335,BUD31,CTR9,TIMELESS,MDFIC,ICE2,YBX1,MAML1,ACAD8,PREB,ZNF189,VOPP1,POLR2I,CIC,LDB1,UTP15,RTF1,ZNF761,SLTM,DAPK3,IRF5,ZNF174,RXRB,NFIL3,TBPL1,PRMT7,NUP62,ZFP90,RUVBL2,RBBP4,HNRNPDL,ZBTB24,ADNP2,TCF12,MBD1,ASH1L,TRAF7,MPHOSPH8,ARID2,FOXM1,DYNLL1,XAB2,ZNF416,SMARCA4,RRAGC,PLAGL2,NSD3,IRF3,CHD1,ZNF121,COMMD8,MEAF6,MXD1,SAP130,RRN3,NRF1,ZBTB21,ZNF473,KMT5C,ZNF302,CD3EAP,AKAP8,RPAP1,TARDBP,CHTOP,UTP4,SAP30L,ZNF770,DVL2,ZNF583,RLIM,CSTF1,KDM3B,POU2AF1,POLR2G,ZNF780B,ZNF500,BTG2,PCGF6,ATXN1,NFATC2,KDM1B,MBD3,SRSF1,ZNF317,RBL1,ZNF700,MAFK,STAT6,ARNTL,ZNF436,DNAJC17,NCOA1,AKNA,MAPK1,BRD9,SMAD4,CBX4,INTS2,NAT14,SLC30A9,DNAJC2,CTDP1,NIFK,CDC40,MTERF1,ZNF316,EYA1,SCYL1,AGO2,ARID5A,KLF13,PAWR,GTF3A,NKRF,MXD4,PAGR1,IRF4,KMT5A,NABP2,BRD7,ANP32A,SS18L1,POLR1B,STAT3,RBM15B,SAMD4B,GTF3C6,RPRD1A,HMGN5,PSPC1,ZNF202,HELB,MIER1,ZMYM5,RCOR1,POLR3GL,PCGF1,MEN1,ZNF407,SYMPK,MAPK3,TFEB,CNOT9,ATAD2,BIRC5,L3MBTL3,TFE3,CDCA7L,BBX,E2F1,KMT2B,RBPJ,SRSF3,TAF12,NR2F2,ZMIZ1,HIPK3,IFI16 |
| 1.324e-10 | -22.75 | GO_REGULATION_OF_MICROTUBULE_POLYMERIZATION_OR_DEPOLYMERIZATION | MSigDB lists | GO_REGULATION_OF_MICROTUBULE_POLYMERIZATION_OR_DEPOLYMERIZATION | 165 | 58 | 17377 | 2626 |
ZNF207,KIF3B,CHMP2A,SKA3,MAPRE1,PDCD6IP,DCTN2,CIB1,XIAP,TPX2,KIF23,MYH9,RACGAP1,HAUS4,CCNB1,RGS2,STMN1,RAB11A,BIRC2,TUBGCP2,HAUS2,SPAG5,FBXO5,KIFC1,STARD9,SMC3,NEK6,PRC1,CDKN1B,ARHGEF2,CEP63,PLK1,PSRC1,RHOA,BIRC3,ASPM,NEK7,TUBGCP5,MYBL2,EZR,AURKB,CHMP2B,BORA,KIF11,HAUS8,KIF2A,MID1IP1,GOLGA2,BIRC5,CHD3,MAP4,CHMP4B,CHEK2,WDR62,ESPL1,TERF1,CSNK1D,TUBB |
| 1.327e-10 | -22.74 | organelle subcompartment | cellular component | GO:0031984 | 1653 | 336 | 18223 | 2701 |
TMED7,RAB14,TMEM203,ADAM10,PIGQ,TMEM109,AGPAT1,TAP1,TGOLN2,IKBIP,RIC1,ASAP2,CYB5RL,AP1M1,DNM2,AP2B1,CISD2,MARCH2,RNF26,TFG,SPTSSA,LRRC59,RHBDD2,MGAT5,PLK3,PGAP2,USO1,RHOBTB3,TMEM115,NRAS,ATG9A,GALNT7,ICMT,MCFD2,SLC50A1,RAB2B,STT3A,TMED10,RPS27A,MYO18A,SARAF,ST3GAL2,CHPF2,RTN3,B4GALT2,SVIP,SCOC,SEC61G,HLA-E,B4GALT1,SLC35B1,TMED3,NOTCH2,TMEM165,PSEN1,COPG2,NPLOC4,COPB2,DDRGK1,CD59,FKBP1A,RPN1,RNF121,LRRC8D,RNFT1,DAD1,TPST1,PIGG,RTCB,PCYT2,PIKFYVE,LPCAT1,PPP6R1,TMED2,FDFT1,NAGPA,EIF5A,GCC2,PIGT,SIGMAR1,RB1CC1,ERO1A,RDH10,MAN1B1,MFNG,USF3,SSR2,GORASP2,GOSR1,CYB5A,PI4K2A,RDH11,DERL1,SEC31A,SCARB2,GOLGA2,NSF,ERGIC3,LPCAT4,ARAP1,VCPIP1,SAMD8,SMPD4,PPP6R3,MAP3K5,RNF139,RHOG,ATXN3,SYS1,GPR89A,RAC1,VTI1A,SLC39A13,TMEM97,RXYLT1,SLC35B2,ADPGK,AP1B1,LCLAT1,KTN1,APP,RAB21,ATP2A2,LPIN2,NSFL1C,TAP2,ANKRD13C,CLN6,GCC1,ANKLE2,SEC61B,ERMP1,ATP13A1,GOPC,CUL3,PKMYT1,TMEM147,DNAJA1,RAB1A,AP4E1,ERC1,SERP1,SEC61A1,DDOST,CERS6,GOLGA8A,SEL1L,NCLN,MBOAT1,ATF6,B4GALT3,CSNK1D,TMBIM4,B4GALT5,AGPAT3,SDF2L1,RAB11A,REEP5,WRB,HLA-A,EBP,PDCD10,FUT8,ST8SIA2,OSTC,TMX1,LYPLA2,MOB4,SPPL2B,SH3GLB1,YIF1A,NUCB1,PLD3,MAGT1,STX18,PML,ASNA1,GPR89B,FAF1,ESYT2,SNAPIN,PIGM,COPA,MOGS,CDIPT,FKBP2,BECN1,SEC16A,RNF103,SSR1,DST,RAB8A,NUP210,CDC42,THADA,RAB35,SRI,ZFYVE27,TECR,DPM1,APH1A,LAP3,PITPNB,ESYT1,KRTCAP2,STX16,RHEB,OPTN,ALG3,MAN2A2,AGPAT2,MIA2,GALNT10,ROCK1,PIEZO1,CLN3,CHPT1,RPS26,NAA60,STARD3NL,PIGN,AGTRAP,GORASP1,DNAJB2,UBXN1,PCSK7,RAB6A,B4GALT4,QSOX2,RHBDD1,C1GALT1,NUS1,PYURF,EI24,ARL6IP1,SLC27A4,BCL2,PREB,KDELR1,CYTH1,TRAPPC9,ERLIN1,NSDHL,ACSL3,SYVN1,VKORC1,ZDHHC3,MOSPD3,GALNT2,GOLGA4,ORMDL2,ZDHHC7,TMEM14A,ECPAS,APOL2,PTDSS1,TMEM106C,CORO7,GNPNAT1,CHERP,COPE,SLC2A1,EXT2,BCAP31,SEC11A,ANKRD28,SAR1A,PPP6C,RPN2,BCAP29,CYB5R1,AHCYL1,CLTB,LMAN1,PDIA6,HTRA2,CHP1,MOSPD1,EBAG9,ACSL5,CLCN3,UBQLN4,TOR1AIP2,PEF1,RHBDF2,SURF4,SCAP,CANT1,AP1S1,REEP4,CHID1,ABCA1,TMEM33,CDS2,GOLIM4,GOLPH3L,VPS45,TMX3,ARFIP2,ARF1,GGA2,DNAJB9,MAN1A1,SPPL2A,KLHL20,SEC24C,RRBP1,SLC35B4,ZDHHC13,YIF1B,ATG13,SLC35A1,CAMK2G,RNF5,B3GALT6,ELOVL5,MLEC,RHOA,ATP2C1,RFFL,COG1,WDR81,PNPLA8,HLA-B,RAB18,SEC23IP,PDCD6,GOLGA7,OSBPL8,SNAP29,GLG1,PGRMC1,PKD2,SPCS3,PLOD3,HRAS |
| 1.339e-10 | -22.73 | GO_REGULATION_OF_CELLULAR_RESPONSE_TO_STRESS | MSigDB lists | GO_REGULATION_OF_CELLULAR_RESPONSE_TO_STRESS | 660 | 161 | 17377 | 2626 |
NUP188,TXN,THOC1,ZDHHC8,PPP1R15B,UBQLN2,MAP1LC3B,BECN1,PARK7,CDK5,PCNA,NUP210,NEK6,CDC42,NUP153,OGG1,SEH1L,MLST8,BAK1,PGAP2,NCK1,RAD51AP1,PBK,EZR,MCL1,UBE2V1,BRCA1,MAP3K4,AXIN1,OGT,ATP6V0C,CLU,CHEK2,CLN3,ATP6V0E1,AAAS,CAPN1,PDCD4,SVIP,TBC1D12,HSPH1,NSMCE4A,SCOC,PHF23,UBXN1,GADD45G,CHCHD2,DNAJB1,EIF2AK4,NUP205,ATP6V0A2,MDFIC,PIKFYVE,LRSAM1,ATP6V0D1,NUP85,TERF2,ZMYND11,PIP4K2C,GBA,BCLAF1,EIF2AK1,ADRB2,SYVN1,PTTG1IP,MAP2K2,PTPRF,MBIP,TSC1,DUSP3,EXOC4,CEBPG,NUP62,MAP3K5,CDKN2A,ATXN3,FEZ2,FOXM1,BCL2L1,ATP6V1B2,DUSP22,LYN,BCAP31,EPM2A,TERF2IP,ATP6V0B,MDM2,RALB,TBC1D14,NUP107,PARL,DVL2,RNF169,HTRA2,ATP6V1G1,UBQLN4,BRD4,RAB7A,MAP4K4,TAOK1,ATP6V0A1,NUP155,DNAJA1,VDAC1,EDEM2,TRIM28,USP36,CHMP4A,VPS26B,HIPK2,GADD45B,ARNTL,H2AFX,CHMP4B,TRIM32,MAPK1,POLQ,USP13,TMEM33,MIF,BCL2L12,DNAJC2,TRIP12,RAE1,EYA1,BABAM1,NUP54,SDF2L1,AKT1S1,PIP4K2A,PTPN2,RPA2,RFWD3,PDCD10,PTEN,FUT8,AXIN2,ARHGEF2,FEM1B,PTGES3,CAMK2G,RNF5,KAT2A,PRKDC,HELB,MEN1,SH3GLB1,PRDX1,HSPA1B,MAPK3,RPA1,MTMR3,ATP6V1D,GPS2,PML,DDX5,PSAP,ATP6V1C1,IGBP1,HRAS,HIPK3 |
| 1.406e-10 | -22.68 | Golgi vesicle transport | biological process | GO:0048193 | 353 | 100 | 17256 | 2622 |
CCDC93,TMED7,RAB14,CORO7,SYS1,COPA,DYNLL1,COPE,ANK3,VTI1A,TGOLN2,KIF2C,SEC16A,BCAP31,ANKRD28,NAPG,RAB8A,SAR1A,RAB35,TBC1D14,PPP6C,DNM2,KIF22,BCAP29,RP2,LMAN1,TFG,DCTN1,SNX8,USO1,TMEM115,GOPC,KIF15,CUL3,BICD2,PITPNB,MCFD2,RAB1A,PEF1,ARF4,OPTN,KIF2A,SURF4,TMED10,MYO18A,MIA2,CSNK1D,DYNC1LI2,KIF3B,GOLPH3L,SCAMP3,GORASP1,DCTN2,SCYL1,NKD2,KLC1,CHIC2,KIF23,RACGAP1,ARF1,TMED3,RAB6A,COPG2,COPB2,CD59,KLHL20,SEC24C,ARF5,CAPZA1,KIFAP3,YIF1B,PPP6R1,MYO5A,TMED2,PREB,KDELR1,SPTAN1,GCC2,TRAPPC9,SNX2,COG1,RABIF,CAPZA2,GOSR1,KIF11,MACF1,YIF1A,SEC31A,SEC23IP,KIF18A,PDCD6,GOLGA4,GOLGA7,GOLGA2,NSF,SNAP23,STX18,EXOC4,PPP6R3,NRBP1 |
| 1.435e-10 | -22.66 | IVANOVA_HEMATOPOIESIS_EARLY_PROGENITOR | MSigDB lists | IVANOVA_HEMATOPOIESIS_EARLY_PROGENITOR | 487 | 127 | 17377 | 2626 |
ZNF76,ZNF496,HNRNPAB,GNPNAT1,NDUFAF2,LAGE3,ENSA,SMARCA4,UBE2Q1,SLC35B2,UBQLN2,C19orf48,LCLAT1,STAM,ANKRD23,ATPAF1,ABL2,MTMR4,MRPS27,SOCS6,SEPT11,LRRC59,ZNRD1,MGAT5,ANKLE2,FYTTD1,METTL1,PPIF,ERCC1,TIMP2,PSMA8,GOPC,TUBGCP5,SMU1,NLN,CDCA2,ABHD11,GALK2,PRKRA,KRTCAP2,OGFR,CBFB,LUC7L,H2AFV,PRPSAP1,EIF3G,TRIM28,TMEM201,ZMYM3,MAP3K4,ALG3,SEC61A1,RAD18,TMED10,TBL3,PRPF4,PDXK,NAA60,MANBA,PDAP1,CDT1,HABP4,DCTN2,TRAK1,STRN4,DHX9,MRPS26,IP6K2,B4GALT4,DCUN1D4,SPR,BZW2,SAC3D1,SPPL2A,UBE2Q2,GART,CTNNBL1,KLHL5,RBM34,SSBP3,PHF14,H2AFY,DDX31,AHCY,SLC38A10,BCL2,TAGLN2,CENPM,LDLRAD3,SGCB,SLC35A1,HDHD2,PPA1,IMPA2,B3GALT6,PPAN,ELOVL5,DDX28,MLEC,CSRP1,FOXK1,PRKDC,WDR18,ZNF574,ILF3,DCTD,GORASP2,SF3A2,PRDX1,CAND1,MFN2,GNAS,ZNF180,SEC23IP,C1orf131,CCDC86,TTLL4,L3MBTL3,PFDN4,CDCA7L,PPP1R11,NUP62,MDH1,ZNF830,GCSH,ALS2,GPATCH4 |
| 1.464e-10 | -22.64 | chromatin organization | biological process | GO:0006325 | 725 | 174 | 17256 | 2622 |
H2AFZ,UBN1,KDM4A,KMT2E,CXXC1,TAF6L,SIRT2,CCNB1,TET3,NOC2L,TAF5L,SMARCE1,DNMT1,ARID4A,CARM1,RYBP,ELOF1,BAZ2A,TLK1,EHMT1,RIOX2,WDHD1,MIER2,WDR82,USP22,PBRM1,AURKB,UTP3,KMT2C,MCM2,USP21,ASF1B,CHAF1A,DOT1L,PAF1,UBTF,BRMS1,BRWD1,BRD2,CHD3,OGT,BAZ1B,ACTB,NAA60,HDAC2,SSRP1,HJURP,MUM1,PRKAA1,CTCF,EZH1,SUPT7L,RLF,CDC73,ARID1B,RB1,MBD2,HDAC7,ZNF335,CTR9,TNRC18,HP1BP3,TSPYL4,ZMYND11,MTA2,LDB1,RTF1,ARID1A,KDM3A,DAPK3,MBIP,NAP1L1,EPOP,SETD3,TEX30,PRMT7,CABIN1,RUVBL2,RBBP4,CDK2,SGF29,CDKN2A,SMARCD1,USP7,MBD1,DNMT3A,ASH1L,ARID2,SUZ12,UBR2,CHD1L,SMARCA4,NSD3,INO80E,CHD1,MEAF6,OIP5,CCNA2,BABAM2,KMT5C,BRPF3,KDM2A,SP100,MTA1,TOP1MT,ATF2,SAP30L,SAP30,KDM3B,BRD4,FAM172A,KAT7,PCGF6,ELP4,KDM1B,H2AFV,MBD3,TRIM28,USP36,CENPU,SUPT16H,RBL1,SAFB,H2AFX,ANP32E,BEND3,NCOA1,H3F3A,PPP5C,BRD9,EYA2,CBX4,DNAJC2,MECP2,EYA1,SHPRH,BABAM1,JMJD6,HMGN3,WDR5,HMG20A,IRF4,SUV39H2,HUWE1,KMT5A,PRDM4,NAA50,ANP32A,H2AFY,KANSL2,SS18L1,CENPM,NAP1L4,FBL,ZFP64,HMGN1,KAT2A,HMGN5,NASP,MIER1,RCOR1,PRMT2,MEN1,PCGF1,CBX3,ATAD2,L3MBTL3,KMT2B,HMGB2,CENPT,TAF12,TAF6,IPO4,DDB1 |
| 1.498e-10 | -22.62 | large_intestine-carcinoma-adenocarcinoma | COSMIC cancer mutations | large_intestine-carcinoma-adenocarcinoma | 16678 | 2536 | 17385 | 2587 |
HECA,ZBTB10,ABCC10,HEXB,TGOLN2,CCNL2,FBXO22,EEF2K,THAP4,RAD23B,ATP13A3,DNM2,ZNRD1,FTSJ3,USP34,CCDC57,ERCC1,NRAS,EHMT1,KIF15,HNRNPF,WDHD1,MIER2,DIDO1,MCM2,RAB22A,SMAD2,MID1IP1,RPS27A,MYO18A,OGT,MPV17,COX5A,SMAD1,ZNF75A,ANXA11,SLC25A33,SEC61G,GGA1,MUM1,CCZ1,TRIO,CUTA,RAB23,KCTD17,HAUS4,EIF2AK4,APH1B,PARN,CDC73,MYL6B,ATG4A,TMEM179B,PDXP,SMC3,GEMIN4,MVP,NUP85,PPP6R1,PABPC1,NSUN4,PPA1,IFRD1,AGGF1,FOXK1,RBM42,GTPBP4,MAP7D1,MRPL16,ELK1,EIF4H,RDH11,MAGED2,KPNA1,ETS2,TYW5,WIPI2,RUFY3,PDLIM5,ACSF2,RHOG,EXOC3,STARD7,C5orf30,VTI1A,INO80E,SLC35B2,LCLAT1,RCOR3,CPNE3,KIAA1147,RBM23,ZNF420,AHCTF1,TBC1D22A,TBC1D14,GMEB1,NSFL1C,SEPT11,GPD1L,ZC3H3,ARL5A,PDCL3,SNX8,ERMP1,EID1,IDH3A,POLR2D,HTATIP2,MEF2D,TMEM147,GSTCD,TANC1,MAT2A,VPS26B,CORO1C,NSMCE2,CAMKMT,PPP5C,PITRM1,TUBB,COMMD10,ZNF445,SRSF6,HABP4,CCM2,FLOT1,BTN3A1,ATG2B,ABHD14B,PPP1R3B,GOLM1,ZBTB45,HUWE1,ZNF260,NAA50,ANXA5,LTN1,UBE3B,NAP1L4,ZNF710,ST8SIA2,RPL22L1,MED22,SPTAN1,STAU1,DDX24,TCTEX1D2,TACC1,MRS2,LDHA,HEBP2,LLPH,RAB3IP,TTC33,PICALM,SH3BP5,SLC19A1,ACOX1,FAM3C,AEN,PARP10,YWHAH,THAP5,GPATCH4,FAM129A,TRIM11,YTHDC2,SNX15,RBM8A,ENSA,NENF,SND1,RUFY1,TRIM65,ZER1,PRNP,KRR1,RAB8A,NUP210,NT5DC1,NOC2L,EIF5,TACC3,RYBP,VPS13B,PTPN18,MIOS,MBLAC2,SNRPB,CDC6,UTP3,PBRM1,ODC1,USP21,TRAM2,FBXO28,BCL7C,ARRDC1,ADAM9,DVL1,NUMB,ZNF564,FUBP1,C1orf74,CTU2,PARP12,ZCCHC9,CENPF,LAMTOR3,CHCHD2,NCKAP1,LYRM2,RSAD1,TNS3,SUB1,RINL,SSBP3,KIF13B,MBD2,XPA,AHCY,RBM3,GLE1,MRPL48,LRSAM1,HDHD2,NTPCR,NSDHL,AMD1,CAMSAP1,ZNF761,METTL22,ICAM2,STYXL1,APPL1,BBS12,ANKRD46,RXRB,SDHB,PCM1,GALNT2,TMEM168,NLRC5,RUVBL2,BTBD10,MYO9A,CCNB2,USP7,GLT8D1,RPLP2,SUCLG1,ARID2,TMX4,SLC2A1,ATP6V1B2,PCBP1,LYN,BCAP31,VAV1,TMEM69,MRPL50,PSMA6,ZNF473,BRPF3,TARDBP,BCAP29,CTDSP2,PRPF19,PPIF,KDM3B,MND1,CLCN3,BIRC3,RAB7A,ANKRD33B,PPIE,CHMP2B,VDAC1,EIF3H,TMEM201,GLOD4,IDE,DHX16,UHRF2,XRCC3,CHMP4B,PARD3,BCL2L12,MCM10,C19orf53,KLHL21,PDAP1,TMX3,CDCA8,GTF3A,ARF1,SLC12A9,TUBGCP2,DNAJB9,HOMER1,WBP1L,POLR1B,RNF5,RBM15B,PPAN,RHOA,RPRD1A,BTAF1,TOP3A,ARHGEF12,PCGF1,DDX23,RAB18,CACNB1,TRIM26,PDCD6,ATP6V1D,L3MBTL3,FAM110A,NEIL3,CTBS,BBX,IMPDH1,TAF12,NR2F2,PGAM1,HIPK3,IFI16,NUP188,TXN,H2AFZ,PNISR,TMEM203,PRKCSH,USP39,UBE2I,PARK7,SLC25A37,ASPHD2,ZNF428,RAB4A,TRA2B,SUCLG2,CISD2,TAF5L,SMARCE1,ZNF800,CDC5L,ZNF524,SGCE,OSBP2,NSUN2,USP22,CLNS1A,EIF3A,ZMYM3,DOT1L,IWS1,ANKRD10,WAS,KIF18B,TPP2,C1orf109,ZMAT3,B4GALT2,PRPF38B,RECQL,C9orf78,EWSR1,GADD45G,RRM1,ACAP1,B4GALT1,CYCS,FAM136A,SUPT7L,TMEM165,CNOT3,NPLOC4,SPAG5,WDR48,RTKN,CEP104,EXOSC7,KLHL5,LRRC8D,PPP4R1,MSH2,PIGG,FBXL7,OSTF1,MRPL40,TNRC18,SYTL3,FAM171A1,APOL1,EIF5A,GCC2,PRIM2,ELL2,RDH10,MFNG,RPS24,GORASP2,CAPZA2,ADRB2,CCT8,MTR,PHF6,PFDN5,SLCO4A1,TTC13,GOLGA2,RBMX,MED15,PIAS2,APPL2,SAMD8,CDKN2A,NUDT3,ZNF511,ATXN3,RAF1,KIAA0232,C2orf49,CD320,EPM2A,CCNA2,MTMR4,BRI3,TP53BP2,AQR,RBM12B,ILKAP,CDK12,SAP30,BRD4,DRAP1,NARF,LRRC8A,ELP4,ABHD11,PKMYT1,ASB13,SERP1,TRIM28,SUPT16H,EIF3K,CHMP4A,CBWD1,ATF6,XRCC4,ADAM23,PRPF4B,NDUFS1,DEPDC1,MECP2,SECISBP2,HMG20A,WWP2,SLC25A36,JAKMIP1,CCNK,DNAJC8,ELP5,AXIN2,CITED2,JMJD4,ANKRD37,KAT2A,TMEM126B,RABIF,ADSL,PACS1,BMS1,KCNQ1,OTUD3,ARSK,MACF1,KIF11,KLF6,COMMD4,SMAP2,FADD,SH3GLB1,MYO1F,CBX3,TMEM127,INF2,PPP1R11,DUSP11,DDX5,WDR62,TAF6,ESPL1,PURA,DDB1,DEF6,IPO4,FAM83G,UBL3,NAT9,PIGM,LYRM4,GPR132,UBE2Q1,PTP4A3,BRIX1,MRPL19,ZNF696,SF3B2,PCYOX1L,CDC42,SYNM,GOT2,JAZF1,HADHB,RPF2,SLC35C2,CNNM3,CARM1,SRPK2,WDR41,LARS,ZCCHC10,CCDC138,LRBA,TMEM216,SUMF2,KMT2C,OGFR,PRPSAP1,ASF1B,RPL37,MAN2A2,EIF4ENIF1,NIP7,U2SURP,MIA2,ZNF268,VPS4A,ATP6V0E1,PPP1R2,PM20D2,XPNPEP3,RGS2,LYAR,FAM89B,POLR2I,TRAFD1,SUGP2,GBA,EIF2A,SYVN1,DAPK3,ARHGAP15,MASTL,UAP1,NFIL3,FN3KRP,YWHAZ,CTSA,TMEM14A,TOB1,TSEN15,ADNP2,TCF12,PRKAB1,MDH2,SMARCA4,ORC1,RRN3,UBXN2A,IARS,CD3EAP,KIF14,EXOSC1,CS,CLTB,DNAL4,CSTF1,POU2AF1,UBQLN4,NXT1,HPDL,PGGT1B,SELPLG,SMU1,ATXN1,GLO1,OGDH,BICD2,CADM1,EDEM2,HERPUD2,TOLLIP,FANCE,MBD3,PDHX,RPS9,ALKBH6,SURF4,DUS3L,ARNTL,ANP32E,FKBP5,TMEM101,CCDC125,ABCA1,PDCD2L,GCLM,RAE1,DCTN2,NUP54,CHIC2,PAWR,MXD4,DCUN1D4,PIP4K2A,XPR1,FERMT3,KIF5B,KLHL20,SEC24C,RRBP1,ARHGEF2,LDLRAD3,C12orf75,STAT3,MYO5A,NIPAL3,AMPD2,TXNL1,PHF20L1,DCAF6,FAM49B,TMEM39A,ATP2C1,RFFL,COG1,RCOR1,PRMT2,TFEB,LEMD2,UPF1,ELMO1,ZC3H7B,DTX4,ZMIZ1,TERF1,HRAS,CCDC93,FGFR1OP,TMED7,PIGQ,AGPAT1,CNTROB,PPP1R16B,MIS12,GSDMB,TTC9C,PDS5B,NUP153,SENP1,PGAP2,TMEM115,PLEKHM3,DCUN1D5,PLEKHF2,BRMS1,PWWP2B,TRIM47,WDR11,AXIN1,SMG9,TRIM52,LONP2,NDUFV2,PHF23,CERK,SLC4A2,EZH1,ITGB5,LMNA,MCTS1,DDX56,EIF2S2,SLC38A5,FOXN2,CARS2,PRRC2A,C16orf72,RB1CC1,ZMYND11,PGS1,MYBL2,UHRF1BP1,SRSF5,MPG,MATR3,CYB5A,NCDN,POLR2J,SETD3,TEX30,CNOT6,NDE1,EGLN1,ZNF207,ANKRD27,PPP1R37,ABCA3,SARNP,IVNS1ABP,RMI2,MON1B,TMEM97,NIT2,NUF2,ZNF267,TCF19,TMEM161B,KTN1,APP,PRKD3,CLUAP1,ATP2A2,UTP18,GRSF1,DUT,ZCCHC2,ANAPC7,RNF19A,FAM76B,CLN6,TMEM9,GCC1,RNF169,ADCY7,ATP6V1G1,ENPP4,RNPS1,CDCA2,FKBP3,GPR137,DDX17,CHCHD3,PEX5,CDC16,HIPK2,MBOAT1,TICAM1,PDXK,ZBTB11,ANXA6,TMBIM4,GMCL1,UBE4A,IL21R,ETS1,WRB,ZNF92,PNO1,CAPN2,ADD3,SUV39H2,TTLL12,TPCN1,TMX1,HNRNPM,LYPLA2,LDHB,PPP3CA,NUDT8,POLK,JTB,EMP3,MTMR12,ZP3,PDE3B,KIF18A,CCDC6,WNT5B,MAPK6,LY75,C4orf46,SLC25A19,RGL1,PSAP,WDR76,IGBP1,FAF1,SNAPIN,COX15,AGRN,THOC1,GNPDA1,GPBP1L1,PPP1R15B,CSNK2A1,EBNA1BP2,GIT2,BIRC2,ATPAF1,DLG5,ABL2,XRCC2,ZFYVE27,MCMBP,PTPRK,CDC37,SP3,METTL1,EXOSC6,HARS,GMFB,ESYT1,ANLN,RAB5B,RHEB,DPYSL3,TBC1D17,TIMM13,CDCA4,TONSL,NRM,NAGLU,ACTB,ZNF45,TMUB1,CTCF,ASAH1,DOCK11,CRLF3,ASXL2,LRRC14,NUS1,SLC27A4,AFF1,MDFIC,MAML1,CYTH1,NQO2,UTP15,EIF2AK1,EIF4G2,ZDHHC3,MOSPD3,ITPRIPL1,CDC27,SNAP23,TBPL1,PRMT7,KCTD7,NDUFA5,CYLD,UGP2,DYNLL1,COPE,HCFC1R1,ZADH2,GGPS1,RPAIN,RAD23A,ABRACL,PDK2,ATP6V0B,STRBP,DUS4L,MRPL34,PDCD2,SAP30L,CLPTM1,SLC39A9,RPL29,RPL35,BTG2,DNAJC9,FRAT2,MTMR6,NFATC2,KDM1B,ARL5B,USP36,CCDC127,MRPL2,ATP1A1,CLK3,MAFK,PSMD3,NDUFA11,CEP55,ZNF436,DNAJC17,NCOA1,SLC25A39,ZC3HC1,ZNF146,ATXN7L2,CDC40,SMAP1,GOLIM4,RRP15,DAP,GNE,SMC6,ARFIP2,NKRF,CHAC2,BZW2,WRNIP1,TMA7,SS18L1,CENPM,PTGES3,CAMK2G,MLEC,ZNF202,PPWD1,FAM50B,RHOT2,NEU1,TPD52L2,GOLGA7,TWSG1,PGRMC1,GLG1,FAM126A,RPS6KC1,UBE2C,PPCS,NDUFB6,TMEM41B,ZDHHC8,PLXNA1,CCNB1,SLC20A1,COMMD6,ABHD14A,POLR3K,C14orf119,ASAP2,SNUPN,CNPY4,TFG,PLCL2,SEH1L,ATG9A,PBK,MKI67,DDX20,AMDHD2,SLC17A5,GALNT7,CCNF,FOXRED1,RBM47,PTER,WDR4,DHTKD1,TRAF5,HDAC2,PWWP2A,HSPH1,LIME1,MAPRE1,CHTF18,ADO,KIF23,SLC35B1,NOTCH2,PMF1,COPG2,JMY,FKBP1A,SLC31A1,SNX18,ATIC,CTPS1,ATP6V0A2,PIKFYVE,RNF135,LPCAT1,EEF1D,TMED2,PHF10,FTL,DDX28,ZNF84,SIGMAR1,PIP4K2C,RIT1,PLEC,KDM3A,SF3A2,FAS,EPRS,ZNF777,TMEM54,QARS,PPP3R1,TCOF1,NRBP1,CABLES1,DNMT3A,RWDD1,CKLF,TRIP10,SF3B1,RPS6KA1,CAST,SUZ12,RAC1,GPR89A,OLA1,SNN,GNB2,FLAD1,APLP2,KDM2A,TNPO2,CDKN1B,TALDO1,GPX4,ATP13A1,MAPRE2,RFC3,ERF,CUL3,SLBP,KIAA1586,H2AFV,POLG2,GAR1,PSMB9,DHX57,NSA2,HSPA4,MRPL55,JAK1,TBL3,GOLGA8A,SEL1L,H2AFX,KLHDC4,B4GALT3,PDCD11,ATMIN,POLQ,POU3F2,OTUD5,NCOR2,ANKRD13D,PKP4,SCAMP3,BABAM1,CDCA3,SLC25A12,BLM,TMCC3,GTF2F1,RPL17,CRAT,AHSA1,PRC1,UPF2,COPS7B,SLC38A10,CNOT6L,CNPY3,UBE2M,IFT46,TMEM160,TSHZ1,ZFP64,STRIP1,DENND4C,DENND1B,WDR18,RPL8,ILF3,LRRC1,RHOT1,TSR2,MARK2,ECH1,PRDX1,PLD3,NUCB1,FBXO21,GNA12,C1orf131,PRDX3,PFDN4,HNRNPH3,STX18,TFDP1,KHSRP,ASNA1,CPEB2,SSSCA1,VPS29,BYSL,S100PBP,MIB2,IER2,PTMS,NOP2,UBN1,DCAF15,NF1,FLYWCH2,ALKBH5,MOGS,UBE2Z,TAF6L,BECN1,MAPK14,SNAPC4,RNF103,BCAT2,MBD4,METTL14,IMPAD1,ZNHIT6,RCSD1,PHTF1,SRI,KIF22,ZBTB22,NFU1,OGG1,TRIM14,COPS8,FYTTD1,TRIM8,RRM2,SOX4,ABHD5,UBTF,CXXC4,PAF1,UEVLD,SPATA2,PQBP1,IARS2,ATXN2L,GALNT10,STARD3NL,RPS15,PIGN,AGTRAP,CIB1,XPO7,SRRT,ZNF449,CAPZA1,GLTP,BCL2,KIFAP3,N4BP2,HP1BP3,VOPP1,THNSL1,ISG15,CAND1,C22orf46,GNAS,TSC1,RBM25,CDCA5,ZFP90,NANP,RBBP4,ZBTB24,SMARCD1,MBD1,WASF2,MMACHC,TOMM20,IFI27L1,GNPNAT1,MPHOSPH8,HNRNPUL2,CHD1,MEAF6,C2orf68,CCDC50,AKAP8,PARL,RPN2,CHTOP,FAM3A,F2R,TMEM14C,SCYL3,ABI1,HTRA2,MOSPD1,RLIM,FAM172A,ZNF500,PSMB7,NLN,WIPF1,BOLA1,BUD13,NDUFB1,PEF1,EIF3G,BTBD1,TAB2,CHCHD1,TULP3,WDR59,CANT1,SCARB1,GAS2,USP11,SMURF1,TSPAN5,PPP2R2D,CDS2,MAGEH1,MRPL42,EYA1,CDK2AP2,MRPS26,LETMD1,KLF13,HDDC2,RGS1,MAN1A1,FBXO5,GART,PELO,TANK,BRD7,MRPL11,SAMD4B,ZDHHC18,POLR3GL,WDR81,MEN1,ZNF407,MFN2,COX8A,ZRANB2,MBD6,SRSF3,ATP6V1C1,IDH3B,TATDN1,TSC2,LACTB2,CMTM6,RBM4,ZNF275,ANKRD39,RPL23A,CDKN2C,NAPG,USF1,MECR,AP1M1,UPRT,CRY2,ECD,RNF26,TIPARP,LRRC59,ANKRD9,RHBDD2,MGAT5,BAK1,ZNF559,RHOBTB3,GABPA,NUTF2,WBP1,GINS4,ARF4,KRIT1,BOLA3,AHNAK,RAD18,PDRG1,RNASEL,CHPF2,OAZ1,SMNDC1,PDCD4,NXT2,HIVEP3,KIAA0100,CLSPN,RHOC,DHX9,PDCD7,PSMD9,HAUS2,COPB2,CD59,TFAP4,RNFT1,RIMS3,MEGF8,EFTUD2,FBXO7,MRPL21,CPSF4,PHKG2,LUC7L2,SRSF11,EIF3L,MTA2,TYW1,USP10,ITM2A,SSR2,BCLAF1,MTX1,SFXN5,FNTA,PDLIM1,TXNDC16,TMEM159,ZNF830,MRPL3,ALS2,TRIM41,KARS,NQO1,POC1A,PTTG1,ANK3,TPX2,TBC1D13,DAZAP2,STMN1,GLRX3,C19orf48,CBWD5,REPS1,ABHD16A,FBXL6,SH3BP1,MTA1,UBA5,CLCN6,INTS12,C8orf59,RPRD1B,CGGBP1,CPNE1,SEC61B,POLR2L,FAM118B,GOPC,CRNKL1,E2F3,CIRBP,RPL38,PFKFB3,GORAB,RAB1A,GIGYF1,TMEM184C,PPP2CA,KIF2A,CCDC14,LSM6,RNF38,DMWD,SNRPG,USP13,ZFP91,IP6K2,WDR5,SLC25A43,PMVK,IFT27,RRP36,NEIL2,SRXN1,RPA2,PSMD2,CLIC4,PDCD10,ITGB8,CBWD2,COQ4,ARF5,ARHGEF1,FBXL19,GTF2H2,TTPAL,UTP20,MAGT1,GPS2,DBI,MRFAP1L1,SSNA1,CD81,TMEM131,WDR13,FANCI,PAPOLA,CREM,FANCL,TET3,GLIS2,IL6ST,INTS1,POP7,SLC44A1,MTPN,ASB6,PLK1,RPP25,CELSR2,SEPT9,RBX1,APH1A,RAD51AP1,CKAP2L,UBE2V1,IL12RB1,EAF2,KRTCAP2,LUC7L,LSG1,NECAP2,C1orf122,ALG3,TRIM4,AGPAT2,CHD3,ZNF367,E2F4,PRPF4,KPNA2,BEND6,CLN3,DNAJC30,FAM208A,NGLY1,POT1,MYL12B,CCDC137,RMND5A,HJURP,FAM53C,DNAJB2,NKD2,SDC2,KLC1,CDK13,ADCK5,COX4I1,RAB6A,DNAJB1,ARID1B,C1GALT1,MLX,UBE2Q2,CCP110,ZNF746,ARL6IP1,CTR9,NIPSNAP1,ABHD2,DCAF8,ACSL3,LDB1,MAP4K3,ARMC8,IRF5,NMT2,RPL36,HAUS8,MBIP,ORMDL2,COX7A2L,ZDHHC7,FAM122A,SIL1,DTD1,UNC13C,BCCIP,SART1,TRAF7,NDUFAF2,TOR1AIP1,ZNF416,LAGE3,TM9SF3,ZFYVE21,RRAGC,ZNF121,OIP5,NRF1,WDR44,PIN1,PPME1,EFCAB11,RPAP1,CABLES2,TOP1MT,LMAN1,AHCYL1,STRAP,SPSB3,ZNF583,SNX25,ARHGAP17,POLR2G,KIAA0040,ZNF780B,PPT1,NUP155,DCLRE1C,MRPS14,RHBDF2,SUGP1,RBL1,FASTK,UBXN2B,STK38,AP1S1,SPRYD4,SLC22A23,H3F3A,CHID1,SMAD4,RAD51D,SLC30A9,NADSYN1,UNK,CMAS,HMGN3,NCAPG,SCYL2,FZD6,HERC3,GTPBP3,CTSS,ORC3,RNLS,YTHDC1,ACP2,CSRP1,HMGN5,METTL5,ABCF2,TUFM,RANGAP1,PNPLA8,HAGH,API5,ZFR,SEC23IP,E2F1,USP20,TMEM219,RBPJ,MAX,PDCD6IP,LUZP1,GXYLT1,ADAM10,CXXC1,TSC22D3,AP3M2,CUL1,GYG1,NANS,OAT,MYEF2,ANKRD26,PA2G4,NOL11,FIZ1,ZNF200,MARCH2,SLC26A2,SRP72,KLF10,LACTB,RFC2,CBFB,RAB2B,PRIM1,MAP3K4,HHEX,RPS14,LUC7L3,MAP4,MRPL27,BTF3,PTPDC1,CCDC59,NMD3,PTOV1,COX5B,DNAJC5,SCOC,DHPS,POLR2K,ANKH,VAV2,C16orf87,PRKAA1,GSPT2,DLGAP4,TATDN3,PXMP2,PRPF39,PSEN1,ZNF79,PDXDC1,VPS25,NDUFS7,YY1AP1,C12orf10,FAM192A,RPN1,LHX8,ARPC5,ZNRF2,DAPK1,TPST1,PIK3IP1,CYC1,SOCS5,FDFT1,PIGT,WDR1,EMB,ZNF574,C1orf35,EXOSC9,ARID1A,PTTG1IP,C9orf40,FXR1,GOSR1,MAP2K2,TWISTNB,AKAP1,XRCC5,HMGN2,PI4K2A,SEC31A,CAT,DERL1,MTHFD2,HSPBP1,CEBPG,ARAP1,USP32,FAM83D,CABIN1,SMPD4,GPI,CYTIP,TP53RK,REPS2,RAB11B,UROD,SLC39A13,POMP,BCL2L1,NUDT19,DECR1,RALB,SIAH1,LPIN2,ADCY9,SOCS6,MRPS27,TTC3,RNASEH2A,CFL1,ANKLE2,CDC123,OAF,VDAC2,EDF1,ERC1,EML4,ANKZF1,ZNF282,RAD51C,DSN1,DDOST,HINT1,DGCR8,SAFB,HAGHL,LMBR1,FTSJ1,RWDD4,NCLN,BEND3,EYA2,DYNC1LI2,B4GALT5,SLC41A1,MANBA,TKT,FAM76A,CBLL1,ARGLU1,LANCL1,POFUT1,FAM8A1,HEATR5B,HLA-A,EBP,RFWD3,NDUFA2,FUT8,FJX1,BTF3L4,PTPN11,MRPL54,FEM1B,RPL19,CNN2,NDUFA3,MTX2,MSH6,PDLIM2,LONRF3,RFXANK,FBXO9,GUF1,RPL32,ZHX1,NDUFS5,WDR91,GPR89B,HIGD2A,ZBED3,RORB,POLA2,ZNF76,MTX3,COPA,UQCR10,HMGXB3,PHRF1,ABCB10,COMMD5,MAP1LC3B,DST,SIVA1,RAB35,GPATCH1,TCEA1,DRAM2,DEAF1,TRAPPC13,SNRNP200,NCK1,LAP3,VHL,SREK1,ARHGDIB,PITPNB,HSPB11,BRWD1,PPM1G,SH3GLB2,CRCP,BAZ1B,CAB39,ACBD4,STK11,CLU,CHEK2,ZSWIM3,TSTD2,MRPL13,CHPT1,DCAF5,CAPN1,UBE2D3,NSMCE4A,PPP1R12A,ZCCHC8,GORASP1,UBXN1,NACA,C19orf25,PCSK7,EPN1,RPL15,THRAP3,TTF1,QSOX2,NUP205,PRPF18,CHKA,DTL,MED10,ZRANB1,MCPH1,SLC12A2,ATP6V0D1,CSNK1G3,CREG1,NUDT4,RPL6,VKORC1,SLTM,EVC2,KLHL15,SIAH2,SLC16A1,EHD4,SNRNP70,C11orf1,APOL2,N4BP2L2,SNX27,CHMP2A,CORO7,FEZ2,UCK2,PMS2,UCK1,CLCC1,EXT2,MXD1,USP5,HNRNPA2B1,SAP130,NVL,PPP6C,CYB5R1,ZNF770,EBAG9,RNF25,PCGF6,METTL2A,FAM72B,PON2,HNRNPR,STAT6,HPS5,MAPK1,BRD9,TMEM33,NAT14,DNAJC2,TRIP12,SHPRH,SCYL1,VPS45,MYO9B,GFM2,SPPL2A,FASTKD3,FGFR3,PPIG,ZDHHC13,TMEM99,H2AFY,ATG13,NDUFS8,ERI3,FBL,FRMD8,SLC35A1,MICAL3,TGFB1,B3GALT6,ELOVL5,HEMK1,TIMMDC1,HELB,PSPC1,MIER1,SCFD2,NDRG3,MTMR3,MEGF9,ACAT1,CENPT,PLOD3,RAB3IL1,ZSWIM6,RAB14,ADD1,MRPS15,KDM4A,XIAP,DHX8,GLUD1,ANKRD23,PABPC4,CALM2,CDK5,PSMD1,NEK6,NSRP1,RABGAP1L,SRSF4,FNIP2,KCNAB2,PCBP2,MLST8,PLK3,ZNF672,HSDL1,MRPL43,TOPORS,MCL1,SMC2,PPFIA3,ICMT,STOML2,LIMK1,ZNF689,PRDX5,ATE1,MLYCD,ATP6V0C,ST3GAL2,FBXL3,TFDP2,E2F2,PFKP,AAAS,DDX42,SSRP1,MRPL9,MRPS2,STRN4,TOP2B,ZNRF3,TMED3,DDRGK1,RAVER2,GNS,INTS7,INPP5A,MCM5,PHF14,ZNF326,UBE2QL1,NAGPA,TIMM8B,ETV3,TSPYL4,TSPAN31,DHX29,TEX10,MAN1B1,RPS10,CBFA2T2,ABCF1,RHOB,LRRC14B,DTWD1,PTPRF,SCARB2,OSBPL11,CCDC86,DUSP3,SLAIN1,MDH1,HEXA,RNF139,SNX14,ZNF296,TRERF1,UBR2,CHD1L,ACTR3,WDTC1,MYH9,CREBL2,NIPA2,PRKACA,SAFB2,ANKIB1,STAM,ARL6IP6,RAB21,SP100,ZKSCAN1,DDA1,NUP107,ANKRD13C,MAVS,CEP63,TMEM136,RBM15,ATF2,DCTN1,SHOC2,PSRC1,MAP4K4,WBP2,ATP6V0A1,NUSAP1,NDUFA7,DNAJA1,TAZ,C19orf54,TAF2,SEC61A1,WDR7,RPLP1,CBLN2,RBMS1,FUS,GEN1,LRP8,COIL,LRCH1,GALK1,ZNF786,RPS2,SESTD1,TRAK1,JMJD6,SIKE1,AKT1S1,KRI1,FBXO3,ERH,GATC,NDUFB4,PPP1R8,PRDM4,GTSE1,GEMIN6,DCP1A,SGCB,S100A6,IMPA2,NUDC,PDPK1,TK1,GUK1,TNFAIP3,GALC,ZNF512,KIAA0930,MRPS10,DDX39A,RPA1,ZNF862,ZNF180,KEAP1,POLE,TATDN2,PITX1,CAPN7,LRPPRC,PML,HMGB2,USF2,ANAPC4,SRM,DDX47,MCCC1,CDC42SE2,S1PR2,CDIPT,SEC16A,SSR1,LIN9,PCNA,ZNF639,PIK3R2,ETV6,TXLNA,PPCDC,FAM86C1,MYBL1,MRPL32,CCAR1,ABCC5,PBXIP1,BAZ2A,TLK1,MRPL12,EZR,LNX2,LRP5,BRCA1,PRKRA,STX16,EPB41,OPTN,SEPT1,SOCS4,QRSL1,PIEZO1,OSGEPL1,GLCCI1,NUDT11,NAA60,GEMIN7,SEPHS2,LZTR1,RACGAP1,PPP3CB,B4GALT4,RLF,RAPGEF6,SNRNP25,RB1,VASP,VMP1,PPIL2,MEA1,TIMELESS,AHDC1,ALDH18A1,TMEM8A,ABCC1,PREB,TRAPPC9,AACS,MEMO1,KRAS,RTF1,UBE4B,NFATC2IP,LY6E,ARPC1A,ZNF174,PSMC4,GOLGA4,PALB2,SYNCRIP,PRPS2,NIPA1,TIGD2,RNF114,FOXM1,MRPL39,XAB2,SUMO2,DUSP22,COMMD8,RPL11,CSDE1,MDM2,CORO1A,MINPP1,METTL9,POC5,DVL2,GM2A,PSMA8,COQ10B,CPOX,TIGD5,SLC26A6,CYP20A1,PRPF3,TXNL4A,RPSA,SRSF1,DNAJC10,ZNF700,SCAP,PLEKHG4B,TIMM17A,FAU,LTA4H,AP2S1,USP53,INTS2,CTDP1,MIF4GD,CDT1,ARID5A,SUMF1,GGA2,AP3S1,CSNK1A1,RMI1,TFRC,PTPN2,IRF4,STARD9,GSTK1,NDUFV1,SLC1A4,CWC27,SLC35B4,DDX31,ABCD1,RPAP3,CNTN5,SNX2,ZMYM5,CCDC34,CHCHD6,BSDC1,KPNA4,CDKN2AIPNL,FBXO41,BIRC5,TFE3,SNAP29,CDCA7L,PKD2,ACADM,CHMP7,SAT2,GCSH,ZNF496,TMEM109,TAP1,YTHDF3,NHLRC3,IKBIP,EIF1B,ELMOD2,KIFC1,DBNDD1,CYB5RL,PARPBP,RNASEK,CDC25B,PRADC1,DNMT1,NOL12,ORAI2,USO1,AKT2,NOL8,GNG7,AURKB,MCFD2,SLC25A5,ZFAND5,STT3A,TMED10,PSMD8,EIF2D,ITGB1,PTPN7,UQCRH,RRS1,ARRB2,RTN3,ZNF598,DDX58,WSB2,PPIB,MUT,GMFG,HLA-E,NDUFA4,MAN2B1,METTL3,CFLAR,NDUFS4,RNF121,MEX3C,KLF16,HDAC7,DAD1,BDH1,PCYT2,GNAI2,ANKHD1,TERF2,MORC3,KCTD20,SEPT8,DCTD,PKM,TOMM40,PATL1,ADSS,SERTAD2,SERF2,ZFP92,NSF,DCK,ERGIC3,ACLY,LPCAT4,VCPIP1,YY1,PPP6R2,MAP3K5,PPP6R3,RNF14,CDK2,ZC3HAV1,ZBTB37,URB2,EIF3D,MAGED1,KLHL18,ADPGK,SLC25A44,AP1B1,SDHA,PAIP2,PHC2,CRKL,MOAP1,TERF2IP,CYHR1,ZNF75D,SHC1,UCHL5,NAA35,TMBIM1,CCT2,CDKN2AIP,MKLN1,HMGN4,GALK2,CDC23,SHCBP1,AP4E1,PRDM11,VEZF1,PPP2R5A,ACYP1,STAT1,PPA2,TRIM32,RHEBL1,R3HCC1L,C1orf112,TCF3,MRI1,BRAP,AGPAT3,MYNN,SDF2L1,SPR,RAB11A,REEP5,FOXO3,MAD2L2,CCDC28A,PIP5K1C,RBM17,MAT2B,PTEN,CENPJ,TAGLN2,OSTC,CREB1,PACS2,NCOA2,SMC4,RNASEH2C,NEK7,NET1,PARP4,TBRG4,ANAPC2,RPL27A,YIF1A,SGSH,HGS,TTLL4,SLC38A7,MFAP1,CCDC69,BRWD3,ESYT2,SKA3,NPHP4,UBE2E2,HNRNPAB,PLXNC1,ST13,TMEM184B,DNAJC24,ZNF107,KIF2C,SLC29A1,AGFG1,SIRT2,FKBP2,USP48,SNRPD3,UBQLN2,CUTC,EDC3,UBLCP1,ZNF804A,RAP1A,THADA,EIF4A3,AP3S2,ATG3,DPYSL2,PPP1R12C,AKR1B1,NDUFB9,JOSD1,RP2,TTC4,TECR,ARID4A,FGFR1OP2,TIMM50,TDP1,DPM1,FOPNL,SLC16A7,WDR82,SLC25A22,STK17B,DHX15,CHAF1A,GEMIN5,COPS6,SASS6,RPS26,PSMC1,SLC12A7,TBC1D12,TM9SF4,ZNF768,UFC1,MED13L,TIA1,MEF2A,EPHX2,PITHD1,RHBDD1,NFATC3,BANF1,BUD31,ZNF335,YBX1,KNTC1,ACAD8,UBE3C,ZNF189,ALDH9A1,KDELR1,TSTA3,CIC,OXR1,PSMA1,TMEM241,SEPT7,NAP1L1,NSMF,ODF2,EXOC4,KIAA1328,NUP62,PITPNA,NAA20,PTDSS1,MZT2B,PDSS2,C7orf26,TMEM106C,IMMT,ASH1L,CHERP,WDYHV1,PLAGL2,CHKB,IRF3,TWF2,PAIP1,ANKRD28,ANKLE1,FARSA,SAR1A,SCAMP4,APOOL,PDIA6,ACSL5,TOR1AIP2,AZI2,GFER,RAD54B,TMEM41A,DAP3,ZNF317,GADD45B,AKNA,REEP4,CBX4,MIF,KIF3B,GOLPH3L,SH2D3A,CASP6,TOR3A,SRGN,DBF4,SAC3D1,CTNNBL1,YIF1B,CLDND1,TTC17,SLC25A1,GINS1,PAQR6,CSNK1G2,TELO2,ADAM17,HMGN1,NASP,ASPM,PPP1R21,PRKAR1B,SYMPK,TARS,SNRPA,MAPK3,HSPA1B,HLA-B,ATAD2,PLAA,ZNF330,OSBPL8,KBTBD7,PREPL |
| 1.519e-10 | -22.61 | DACOSTA_UV_RESPONSE_VIA_ERCC3_UP | MSigDB lists | DACOSTA_UV_RESPONSE_VIA_ERCC3_UP | 294 | 87 | 17377 | 2626 |
NOP2,UROD,TMX4,TMEM109,AP3M2,GLUD1,RBM4,ABHD14A,RNF103,CREM,MBD4,MOAP1,CDKN2C,RAB8A,PCNA,SYNM,ZKSCAN1,CYB5R1,CLTB,OGG1,BAK1,PPIF,ERCC1,BTG2,PPIE,FRAT2,CDC6,PKMYT1,OGFR,STX16,RFC2,MAT2A,BRMS1,HHEX,BRD2,AGPAT2,ACYP1,CLK3,PSMD8,PQBP1,NCLN,PRPF4,ARRB2,AP2S1,CBX4,EWSR1,HLA-E,PDAP1,CDT1,ADO,RGS2,SPR,FAM8A1,NDUFS7,HLA-A,SAC3D1,FKBP1A,RPN1,FGFR3,NDUFV1,MCM5,MEA1,PTPN11,EEF1D,TERF2,TK1,SIGMAR1,CREG1,MYBL2,LY6E,SNRPA,POLR2A,NEU1,NCDN,ISG15,RBM38,RHOB,PLD3,GALNT2,DUSP3,ZNF330,ERGIC3,OAZ2,E2F1,ASNA1,CDK2,TOB1 |
| 1.578e-10 | -22.57 | cellular component disassembly | biological process | GO:0022411 | 426 | 115 | 17256 | 2622 |
CHMP2A,NDC1,NUP188,ARID2,MRPS15,ADAM10,MRPL39,SMARCA4,KIF2C,CCNB1,MAP1LC3B,STMN1,BECN1,TWF2,MRPL19,MRPL50,NUP210,NEK6,KIF14,ATG3,NUP107,MRPS27,MRPL34,NUP153,CISD2,SMARCE1,MRPL32,CFL1,SEH1L,DVL2,MRPL57,DCTN1,PLK1,PLK3,TIMP2,ATG9A,MRPL43,MRPL12,FRAT2,NUP155,LRP5,PBRM1,CHMP2B,MRPS14,SUPT16H,KIF2A,MRPL2,DAP3,MRPL55,KIF18B,CHCHD1,AXIN1,MRPL27,EIF2D,VIPAS39,DVL1,VPS4A,CLN3,MRPL13,AAAS,CAPN1,MRPL9,LIME1,MRPL42,MRPS2,RAE1,GSPT2,FLOT1,MRPS26,NUP54,KLC1,ATG2B,CSNK1A1,GFM2,NUP205,LMNA,MCTS1,ATG4A,KIF5B,CAPN2,CTSS,BANF1,FBXO7,PELO,MRPL54,ATG13,MRPL48,MRPL40,MRPL21,MRPL11,NUP85,MICAL3,RB1CC1,WDR1,MRPS10,MRPL16,ARID1A,MARK2,CTSL,KIF18A,KPNA1,GOLGA2,NSF,SNAP29,NUP62,HMGB2,WIPI2,WDR45B,CCNB2,CHMP7,MRPL3,NUP58,SNX14,SNAPIN,SMARCD1 |
| 1.590e-10 | -22.56 | GO_MEMBRANE_ORGANIZATION | MSigDB lists | GO_MEMBRANE_ORGANIZATION | 841 | 195 | 17377 | 2626 |
RAB14,PDCD6IP,NUP188,AGRN,CCNB1,BECN1,SEC16A,SSR1,RPL23A,CDK5,RAB8A,NAPG,NUP210,NEK6,ATG3,SIVA1,ZFYVE27,AP2B1,NUP153,TFG,SEH1L,TIMM50,SRP72,BAK1,PLK1,SGCE,USO1,ATG9A,AKT2,EZR,MCFD2,ICMT,SLC25A5,STX16,OPTN,STOML2,RPL37,TRAM2,TMED10,RPS27A,RPS14,MYO18A,ITGB1,ROCK1,VPS4A,CLU,DVL1,CLN3,RPS26,AAAS,RPS15,GORASP1,NKD2,RPL15,RAPGEF6,LMNA,NUP205,ATG4A,CD59,BANF1,PPIL2,ARL6IP1,BCL2,LRSAM1,PPP6R1,NUP85,SYTL3,TMED2,PREB,GCC2,TRAPPC9,RPS10,RPL6,SSR2,RPS24,GOSR1,RPL36,SEC31A,GOLGA4,FNTA,GOLGA2,NSF,SNAP23,PPP3R1,VCPIP1,NUP62,YWHAZ,PPP6R3,CCNB2,CHMP2A,IMMT,TOMM20,SYS1,RPLP2,RAB11B,DYNLL1,RAC1,ANK3,TOR1AIP1,VTI1A,MYH9,BCL2L1,RPL11,ANKRD28,MOAP1,UBXN2A,ATP2A2,NSFL1C,PPP6C,NUP107,TARDBP,TP53BP2,LMAN1,ATF2,PPIF,ANKLE2,RPL29,RPL35,PPT1,RAB7A,CUL3,RPL38,TOR1AIP2,NUP155,RAB1A,CHMP2B,TAZ,SERP1,RPS9,RPSA,PPP2CA,CHCHD3,HSPA4,CHMP4A,PEX5,SEC61A1,TULP3,UBXN2B,RPLP1,CHMP4B,FAU,SMURF1,REEP4,TSPAN5,AP2S1,EYA2,ABCA1,CSNK1D,PARD3,RPS2,RAE1,FLOT1,NUP54,ARF1,RAB11A,WRB,PTEN,RPL17,SEC24C,RPL19,STAT3,SGCB,PACS2,MYO5A,DENND4C,RPL8,HEBP2,RABIF,PACS1,RAB3IP,RHOT1,RPL27A,RHOT2,MACF1,CHCHD6,PICALM,SH3GLB1,MFN2,LEMD2,HGS,SEC23IP,GOLGA7,RPL32,ELMO1,OSBPL8,SNAP29,STX18,TFDP1,E2F1,ASNA1,FAM126A,SSNA1,CHMP7,YWHAH,SNAPIN |
| 1.608e-10 | -22.55 | protein sumoylation | biological process | GO:0016925 | 76 | 35 | 17256 | 2622 |
NDC1,NUP188,RAE1,EYA1,SUMO2,CDCA8,NUP54,TOP2B,UBE2I,NUP205,PCNA,NUP210,MDM2,MTA1,HDAC7,NUP107,NUP153,SENP1,NUP85,SEH1L,SP3,NUP155,RANGAP1,TOPORS,KIAA1586,NFATC2IP,AURKB,TRIM28,BIRC5,NSMCE2,PIAS2,NUP62,NUP58,CBX4,AAAS |
| 1.608e-10 | -22.55 | chromosome localization | biological process | GO:0050000 | 76 | 35 | 17256 | 2622 |
CHMP2A,PDCD6IP,CDT1,CENPF,ACTR3,CDCA8,NUF2,KIF2C,CCNB1,SPDL1,BECN1,RAB11A,MIS12,KIFC1,ANKLE1,KIF14,KIF22,SEH1L,PSRC1,CUL3,CDC23,CHMP2B,LEMD2,CHMP4A,KIF18A,CDCA5,CEP55,FAM83D,NUP62,CHMP4B,VPS4A,RRS1,NDE1,CHMP7,TERF1 |
| 1.654e-10 | -22.52 | mitochondrion organization | biological process | GO:0007005 | 441 | 118 | 17256 | 2622 |
NDUFA5,TOMM20,IMMT,MTX3,NDUFB6,NDUFAF2,UQCR10,DYNLL1,GLUD1,BCL2L1,MAP1LC3B,ATP5PF,BECN1,PARK7,ATPAF1,MIEF1,MOAP1,CDK5,MTFR1L,NRF1,TIMM23,ATG3,DNM2,NDUFB9,CISD2,TP53BP2,APOOL,ATF2,HTRA2,TIMM50,BAK1,PPIF,ATG9A,GABPA,DMAC2,MCL1,NDUFA7,NDUFB1,SLC25A5,TAZ,POLG2,FOXRED1,STOML2,CHCHD3,HSPA4,TIMM13,TIMM29,TIMM17A,NDUFA11,CAMKMT,MPV17,CLU,TFDP2,PITRM1,EYA2,SLC25A33,GCLM,NDUFV2,NDUFS1,MTERF1,PHB2,TWNK,TRAK1,CHCHD2,TIMM21,MEF2A,ATG2B,CYCS,ATP5F1B,NDUFS7,ATG4A,SLC25A36,NDUFS4,NDUFAF6,FASTKD3,NDUFV1,NDUFA2,NDUFB4,FBXO7,BCL2,ATG13,NDUFS8,PIKFYVE,NDUFA3,STAT3,MTX2,TIMM8B,ATP5IF1,COA3,KAT2A,TIMMDC1,RB1CC1,TMEM126B,MTFR2,GBA,JTB,HEBP2,MTX1,WDR81,RHOT1,TOMM40,ATP5MF,RHOT2,MARK2,CHCHD6,MFN2,ATP5MC3,PRDX3,TFDP1,E2F1,PPP3R1,YWHAZ,NDUFS5,ATP5F1A,WIPI2,TMEM14A,YWHAH,WDR45B |
| 1.654e-10 | -22.52 | GSE46606_UNSTIM_VS_CD40L_IL2_IL5_3DAY_STIMULATED_IRF4MID_SORTED_BCELL_UP | MSigDB lists | GSE46606_UNSTIM_VS_CD40L_IL2_IL5_3DAY_STIMULATED_IRF4MID_SORTED_BCELL_UP | 187 | 63 | 17377 | 2626 |
MBD1,CCDC93,GLT8D1,LIME1,GXYLT1,UBN1,SNX15,TMEM109,PMS2,ACAP1,IRF3,CDC42SE2,XPO7,ASXL2,SYNRG,GIT2,FBXO22,DDRGK1,SLC25A36,TMEM179B,ZBTB45,SH3BP1,TBC1D14,NDUFS8,GLTP,ZBTB22,ANAPC7,FBL,TOP1MT,GPD1L,CTDSP2,NIPAL3,SP3,ERMP1,TSPYL4,PPP1R21,ZMYM5,MAP4K4,UBE4B,TMEM147,MCFD2,VKORC1,SERP1,BTBD1,BBS12,CLNS1A,SMAP2,ECH1,CBX3,PON2,HHEX,TSC1,SGSH,TTC13,POLR2J,TMED10,MYO18A,WDR7,NDUFS5,YY1,DCAF5,ATP6V0E1,PDF |
| 1.655e-10 | -22.52 | HIST1H3E (histone cluster 1 H3 family member e) | protein interactions | 8353 | 200 | 69 | 17029 | 2761 |
SART1,DNMT3A,CHERP,ARID2,SF3B1,SMARCA4,SNRPD3,SF3B2,SPINDOC,PCNA,NSRP1,SMARCE1,DNMT1,CCAR1,RPL29,RPL35,PFKFB3,DNAJC9,PRPF3,PBRM1,MCM2,MBD3,MAT2A,ASF1B,CHAF1A,SUPT16H,HSPA4,RPS27A,TONSL,RPS14,STK38,U2SURP,PRPF4,RPS26,SSRP1,THRAP3,LMNA,RBM17,ERH,SMC3,RPL17,MCM5,BRD7,RPL19,PABPC1,SPTAN1,PHF10,NASP,PRRC2A,MTA2,PRKDC,ILF3,RPS10,BMS1,BCLAF1,RPL27A,SF3A2,CBX3,RPL36,XRCC5,RBM25,RPL32,CCDC86,TCOF1,RBBP4,SNRNP70,CD81,IPO4,SMARCD1 |
| 1.768e-10 | -22.46 | BYSTRYKH_HEMATOPOIESIS_STEM_CELL_QTL_TRANS | MSigDB lists | BYSTRYKH_HEMATOPOIESIS_STEM_CELL_QTL_TRANS | 842 | 195 | 17377 | 2626 |
H2AFZ,COPA,ADAM10,UBN1,UBE2Z,USP39,ABCB10,AGFG1,GYG1,UBE2I,SEC16A,PARK7,RNF103,UBLCP1,PSMD1,IL6ST,PPP1R12C,SRI,AKR1B1,FBXW2,JOSD1,CRY2,MYBL1,FTSJ3,PCBP2,SRSF10,FYTTD1,SLC16A7,MRPL12,WBP1,DCUN1D5,SLC25A5,CBFB,LUC7L,FOXRED1,UBTF,HSPB11,CDCA4,BRD2,STT3A,PDRG1,NIP7,LIMK1,AXIN1,COX5A,BTF3,ROCK1,SMAD1,MRPL13,RTN3,SMNDC1,NUMB,RECQL,NDUFV2,DNAJB2,STRN4,DHX9,RAB23,KLC1,XPO7,PSMD9,PITHD1,PDXDC1,LMNA,RTKN,SUB1,DDX56,C4orf3,INPP5A,ARPC5,DAD1,MBD2,PPIL2,ZNF746,MEA1,GLTP,AHCY,MRPL48,KDELR1,TERF2,FDFT1,TIMM8B,POLR2I,NSDHL,MRPL16,ARID1A,FXR1,ICAM2,ABCF1,MATR3,NMT2,ANKRD46,ADSS,GNAS,NAP1L1,FNTA,SNAP23,COX7A2L,CEBPG,MDH1,WIPI2,RNF14,DNMT3A,NQO1,RAB11B,CHD1L,HNRNPUL2,PTTG1,PMS2,SLC25A44,ATP6V1B2,CHD1,CD320,CRKL,VAV1,MRPL50,RRN3,DDA1,ADCY9,UBA5,PPP6C,CYB5R1,ATF2,CTDSP2,DVL2,PDCL3,HTRA2,CGGBP1,BRD4,POLR2G,WBP2,PSMB7,WIPF1,NUSAP1,GLO1,OGDH,MBD3,GAR1,PEX5,ATP1A1,HNRNPR,VPS26B,STAT6,HIPK2,TULP3,STK38,FASTK,ZNF436,PDXK,CSNK1D,SLC30A9,CTDP1,CDS2,TOR3A,TCF3,MYNN,GTF3A,IFT27,RAB11A,TFRC,CAPN2,RPA2,GSTK1,PSMD2,NDUFV1,COQ4,AXIN2,MRPL54,STAT3,IMPA2,MYO5A,MED22,STAU1,CSRP1,KIAA0930,ADSL,GUF1,NEU1,MYO1F,KEAP1,NEK1,ATP6V1D,SEC23IP,CCDC6,TWSG1,ACOX1,CDCA7L,CAPN7,SLC25A19,IMPDH1,ZRANB2,PSAP,RBPJ,SNAPIN,DDX52 |
| 1.775e-10 | -22.45 | GSE4984_GALECTIN1_VS_VEHICLE_CTRL_TREATED_DC_DN | MSigDB lists | GSE4984_GALECTIN1_VS_VEHICLE_CTRL_TREATED_DC_DN | 183 | 62 | 17377 | 2626 |
NDUFV2,IMMT,PLXNC1,HNRNPAB,SUZ12,DCTN2,KCTD17,CHAC2,POLR3K,TFRC,SPAG5,SSR1,MCTS1,PRNP,HNRNPA2B1,RPA2,RPN1,CLIC4,SHC1,IL6ST,ZDHHC13,NSFL1C,MSH2,CTR9,KNTC1,PTGES3,APOOL,SPTSSA,PPA1,TMED2,ALDH9A1,SRSF10,TXNL1,METTL1,SLC39A9,ADAM17,TRAFD1,NASP,CREG1,HARS,WDR1,CPOX,TOP3A,E2F3,TOMM40,PEF1,CCT8,LSG1,RHEB,GINS4,SEC23IP,PLAA,ATAD2,LSM6,TFE3,HPS5,MRPL27,FTSJ1,CAB39,KPNA2,BTBD10,IFI16 |
| 1.895e-10 | -22.39 | ductal_carcinoma | COSMIC cancer mutations | ductal_carcinoma | 16293 | 2492 | 17385 | 2587 |
HECA,ZBTB10,ABCC10,HEXB,TGOLN2,CCNL2,FBXO22,EEF2K,THAP4,RAD23B,ATP13A3,DNM2,ZNRD1,FTSJ3,USP34,CCDC57,ERCC1,NRAS,EHMT1,KIF15,HNRNPF,WDHD1,MIER2,DIDO1,MCM2,RAB22A,SMAD2,MID1IP1,RPS27A,MYO18A,OGT,MPV17,COX5A,SMAD1,ZNF75A,ANXA11,SLC25A33,SEC61G,GGA1,MUM1,CCZ1,TRIO,CUTA,RAB23,KCTD17,HAUS4,EIF2AK4,APH1B,CDC73,MYL6B,ATG4A,TMEM179B,PDXP,SMC3,GEMIN4,MVP,NUP85,PPP6R1,PABPC1,NSUN4,PPA1,IFRD1,AGGF1,FOXK1,RBM42,GTPBP4,MAP7D1,MRPL16,ELK1,EIF4H,RDH11,MAGED2,KPNA1,ETS2,TYW5,WIPI2,RUFY3,PDLIM5,ACSF2,RHOG,EXOC3,STARD7,C5orf30,VTI1A,INO80E,SLC35B2,RCOR3,LCLAT1,CPNE3,KIAA1147,RBM23,ZNF420,AHCTF1,TBC1D22A,TBC1D14,GMEB1,NSFL1C,SEPT11,GPD1L,ZC3H3,ARL5A,PDCL3,SNX8,ERMP1,EID1,IDH3A,POLR2D,HTATIP2,MEF2D,TMEM147,GSTCD,TANC1,MAT2A,VPS26B,NSMCE2,CORO1C,CAMKMT,PPP5C,PITRM1,TUBB,COMMD10,ZNF445,SRSF6,HABP4,CCM2,FLOT1,BTN3A1,ATG2B,ABHD14B,PPP1R3B,ZBTB45,HUWE1,ZNF260,NAA50,ANXA5,LTN1,UBE3B,NAP1L4,ZNF710,ST8SIA2,SPTAN1,STAU1,TCTEX1D2,DDX24,TACC1,MRS2,LDHA,HEBP2,LLPH,RAB3IP,TTC33,PICALM,SH3BP5,SLC19A1,ACOX1,FAM3C,AEN,PARP10,YWHAH,THAP5,GPATCH4,FAM129A,TRIM11,YTHDC2,SNX15,RBM8A,ENSA,NENF,SND1,RUFY1,TRIM65,ZER1,PRNP,KRR1,RAB8A,NUP210,NT5DC1,NOC2L,EIF5,TACC3,VPS13B,PTPN18,MIOS,MBLAC2,SNRPB,CDC6,UTP3,PBRM1,ODC1,USP21,TRAM2,FBXO28,BCL7C,ARRDC1,ADAM9,DVL1,NUMB,ZNF564,FUBP1,C1orf74,CTU2,PARP12,ZCCHC9,CENPF,LAMTOR3,CHCHD2,NCKAP1,LYRM2,RSAD1,TNS3,SUB1,RINL,SSBP3,KIF13B,MBD2,XPA,AHCY,RBM3,MRPL48,LRSAM1,HDHD2,NTPCR,NSDHL,AMD1,CAMSAP1,ZNF761,METTL22,ICAM2,STYXL1,APPL1,BBS12,RXRB,SDHB,PCM1,GALNT2,TMEM168,NLRC5,RUVBL2,MYO9A,BTBD10,CCNB2,USP7,GLT8D1,RPLP2,SUCLG1,ARID2,TMX4,SLC2A1,ATP6V1B2,PCBP1,LYN,BCAP31,VAV1,TMEM69,MRPL50,PSMA6,ZNF473,ZNF302,BRPF3,TARDBP,BCAP29,CTDSP2,PRPF19,PPIF,KDM3B,MND1,CLCN3,BIRC3,RAB7A,ANKRD33B,PPIE,CHMP2B,VDAC1,EIF3H,TMEM201,GLOD4,IDE,DHX16,UHRF2,CHMP4B,XRCC3,PARD3,BCL2L12,C19orf53,MCM10,KLHL21,PDAP1,TMX3,CDCA8,ARF1,SLC12A9,TUBGCP2,DNAJB9,HOMER1,WBP1L,POLR1B,RNF5,RBM15B,PPAN,RHOA,RPRD1A,BTAF1,TOP3A,ARHGEF12,PCGF1,DDX23,RAB18,CACNB1,TRIM26,PDCD6,ATP6V1D,L3MBTL3,FAM110A,NEIL3,CTBS,BBX,IMPDH1,TAF12,NR2F2,PGAM1,HIPK3,IFI16,NUP188,TXN,H2AFZ,PRKCSH,USP39,UBE2I,PARK7,SLC25A37,ASPHD2,ZNF428,RAB4A,TRA2B,SUCLG2,TAF5L,SMARCE1,ZNF800,CDC5L,ZNF524,SGCE,OSBP2,NSUN2,USP22,CLNS1A,EIF3A,ZMYM3,DOT1L,IWS1,ANKRD10,WAS,KIF18B,TPP2,C1orf109,ZMAT3,B4GALT2,PRPF38B,RECQL,C9orf78,EWSR1,GADD45G,RRM1,ACAP1,B4GALT1,CYCS,FAM136A,SUPT7L,TMEM165,CNOT3,WDR48,SPAG5,RTKN,CEP104,EXOSC7,KLHL5,LRRC8D,PPP4R1,MSH2,PIGG,FBXL7,OSTF1,MRPL40,TNRC18,SYTL3,FAM171A1,APOL1,EIF5A,GCC2,PRIM2,ELL2,RDH10,MFNG,RPS24,GORASP2,CAPZA2,ADRB2,CCT8,MTR,PHF6,PFDN5,SLCO4A1,TTC13,GOLGA2,RBMX,PIAS2,APPL2,SAMD8,NUDT3,CDKN2A,ZNF511,ATXN3,RAF1,KIAA0232,C2orf49,CD320,EPM2A,CCNA2,MTMR4,BRI3,TP53BP2,AQR,RBM12B,ILKAP,CDK12,SAP30,BRD4,DRAP1,NARF,LRRC8A,ELP4,ABHD11,PKMYT1,ASB13,SERP1,TRIM28,SUPT16H,EIF3K,CHMP4A,CBWD1,ATF6,XRCC4,ADAM23,PRPF4B,NDUFS1,DEPDC1,MECP2,SECISBP2,HMG20A,WWP2,JAKMIP1,SLC25A36,CCNK,DNAJC8,AXIN2,CITED2,JMJD4,ANKRD37,KAT2A,TMEM126B,RABIF,ADSL,PACS1,BMS1,KCNQ1,ARSK,MACF1,KIF11,COMMD4,KLF6,SMAP2,FADD,SH3GLB1,MYO1F,CBX3,TMEM127,INF2,PPP1R11,DUSP11,DDX5,WDR62,TAF6,ESPL1,PURA,DDB1,DEF6,FAM83G,IPO4,UBL3,NAT9,PIGM,LYRM4,GPR132,UBE2Q1,PTP4A3,BRIX1,MRPL19,ZNF696,SF3B2,PCYOX1L,CDC42,GOT2,JAZF1,HADHB,RPF2,SLC35C2,CNNM3,CARM1,SRPK2,WDR41,LARS,ZCCHC10,CCDC138,LRBA,SUMF2,KMT2C,OGFR,PRPSAP1,ASF1B,RPL37,MAN2A2,EIF4ENIF1,NIP7,U2SURP,MIA2,ATP6V0E1,PPP1R2,PM20D2,XPNPEP3,RGS2,LYAR,FAM89B,POLR2I,TRAFD1,SUGP2,GBA,EIF2A,SYVN1,DAPK3,ARHGAP15,MASTL,UAP1,NFIL3,FN3KRP,YWHAZ,CTSA,TMEM14A,TOB1,TSEN15,ADNP2,TCF12,PRKAB1,MDH2,SMARCA4,ORC1,RRN3,UBXN2A,IARS,CD3EAP,KIF14,EXOSC1,CS,CLTB,DNAL4,CSTF1,POU2AF1,UBQLN4,NXT1,HPDL,PGGT1B,SELPLG,SMU1,ATXN1,GLO1,OGDH,BICD2,CADM1,EDEM2,HERPUD2,TOLLIP,FANCE,MBD3,PDHX,RPS9,ALKBH6,SURF4,DUS3L,ARNTL,ANP32E,FKBP5,TMEM101,CCDC125,ABCA1,PDCD2L,GCLM,RAE1,DCTN2,NUP54,CHIC2,PAWR,MXD4,DCUN1D4,PIP4K2A,XPR1,KIF5B,KLHL20,SEC24C,RRBP1,ARHGEF2,LDLRAD3,STAT3,MYO5A,NIPAL3,AMPD2,TXNL1,PHF20L1,DCAF6,FAM49B,TMEM39A,ATP2C1,RFFL,COG1,RCOR1,PRMT2,TFEB,LEMD2,UPF1,ELMO1,ZC3H7B,DTX4,ZMIZ1,TERF1,HRAS,CCDC93,FGFR1OP,TMED7,PIGQ,AGPAT1,CNTROB,PPP1R16B,MIS12,GSDMB,TTC9C,PDS5B,NUP153,SENP1,PGAP2,TMEM115,PLEKHM3,DCUN1D5,PLEKHF2,BRMS1,PWWP2B,TRIM47,WDR11,AXIN1,SMG9,TRIM52,LONP2,NDUFV2,PHF23,CERK,SLC4A2,EZH1,ITGB5,LMNA,MCTS1,DDX56,EIF2S2,SLC38A5,FOXN2,CARS2,PRRC2A,C16orf72,RB1CC1,ZMYND11,PGS1,MYBL2,UHRF1BP1,SRSF5,MPG,MATR3,CYB5A,NCDN,POLR2J,SETD3,PTAR1,CNOT6,NDE1,EGLN1,ZNF207,ANKRD27,ABCA3,SARNP,IVNS1ABP,MON1B,RMI2,TMEM97,NIT2,NUF2,ZNF267,TCF19,TMEM161B,KTN1,APP,PRKD3,CLUAP1,ATP2A2,UTP18,GRSF1,DUT,ZCCHC2,ANAPC7,RNF19A,FAM76B,CLN6,TMEM9,GCC1,RNF169,ADCY7,ATP6V1G1,ENPP4,RNPS1,CDCA2,FKBP3,GPR137,DDX17,CHCHD3,PEX5,CDC16,HIPK2,MBOAT1,TICAM1,PDXK,ZBTB11,ANXA6,TMBIM4,GMCL1,UBE4A,IL21R,ETS1,WRB,ZNF92,PNO1,CAPN2,ADD3,SUV39H2,TTLL12,TPCN1,TMX1,LYPLA2,HNRNPM,LDHB,PPP3CA,NUDT8,POLK,JTB,EMP3,MTMR12,ZP3,PDE3B,KIF18A,CCDC6,WNT5B,MAPK6,C4orf46,LY75,SLC25A19,RGL1,PSAP,WDR76,IGBP1,FAF1,SNAPIN,COX15,AGRN,THOC1,GNPDA1,GPBP1L1,PPP1R15B,CSNK2A1,EBNA1BP2,GIT2,BIRC2,ATPAF1,DLG5,ABL2,XRCC2,ZFYVE27,MCMBP,PTPRK,CDC37,SP3,METTL1,EXOSC6,HARS,GMFB,ESYT1,ANLN,RAB5B,RHEB,DPYSL3,TBC1D17,TIMM13,CDCA4,TONSL,NRM,NAGLU,ACTB,ZNF45,TMUB1,CTCF,ASAH1,DOCK11,CRLF3,ASXL2,LRRC14,NUS1,SLC27A4,AFF1,MDFIC,MAML1,CYTH1,NQO2,UTP15,EIF2AK1,EIF4G2,ZDHHC3,MOSPD3,ITPRIPL1,CDC27,SNAP23,TBPL1,PRMT7,KCTD7,NDUFA5,CYLD,UGP2,DYNLL1,COPE,HCFC1R1,ZADH2,GGPS1,RPAIN,RAD23A,PDK2,ATP6V0B,STRBP,DUS4L,MRPL34,PDCD2,SAP30L,SLC39A9,CLPTM1,RPL29,RPL35,BTG2,DNAJC9,MTMR6,FRAT2,NFATC2,KDM1B,ARL5B,USP36,CCDC127,MRPL2,ATP1A1,CLK3,PSMD3,MAFK,NDUFA11,CEP55,ZNF436,DNAJC17,NCOA1,SLC25A39,ZC3HC1,ZNF146,ATXN7L2,CDC40,SMAP1,GOLIM4,RRP15,DAP,GNE,SMC6,ARFIP2,NKRF,CHAC2,BZW2,WRNIP1,SS18L1,CENPM,PTGES3,CAMK2G,MLEC,ZNF202,PPWD1,FAM50B,RHOT2,NEU1,TPD52L2,GOLGA7,TWSG1,PGRMC1,GLG1,FAM126A,RPS6KC1,UBE2C,PPCS,NDUFB6,TMEM41B,ZDHHC8,PLXNA1,CCNB1,SLC20A1,COMMD6,ABHD14A,POLR3K,C14orf119,ASAP2,SNUPN,PLCL2,TFG,SEH1L,ATG9A,PBK,MKI67,DDX20,AMDHD2,GALNT7,SLC17A5,CCNF,FOXRED1,PTER,WDR4,DHTKD1,TRAF5,HDAC2,PWWP2A,HSPH1,LIME1,MAPRE1,CHTF18,ADO,KIF23,SLC35B1,NOTCH2,PMF1,JMY,FKBP1A,SLC31A1,SNX18,ATIC,ATP6V0A2,PIKFYVE,RNF135,LPCAT1,EEF1D,TMED2,PHF10,FTL,DDX28,ZNF84,SIGMAR1,PIP4K2C,RIT1,PLEC,KDM3A,SF3A2,FAS,EPRS,ZNF777,TMEM54,QARS,PPP3R1,TCOF1,NRBP1,CABLES1,DNMT3A,RWDD1,CKLF,TRIP10,SF3B1,RPS6KA1,SUZ12,CAST,RAC1,GPR89A,OLA1,SNN,GNB2,FLAD1,APLP2,KDM2A,TNPO2,CDKN1B,TALDO1,GPX4,ATP13A1,MAPRE2,RFC3,ERF,CUL3,SLBP,KIAA1586,H2AFV,POLG2,GAR1,PSMB9,DHX57,NSA2,HSPA4,MRPL55,JAK1,TBL3,GOLGA8A,SEL1L,H2AFX,KLHDC4,B4GALT3,PDCD11,ATMIN,POLQ,POU3F2,OTUD5,NCOR2,ANKRD13D,PKP4,SCAMP3,CDCA3,SLC25A12,BLM,TMCC3,GTF2F1,RPL17,CRAT,AHSA1,PRC1,UPF2,COPS7B,SLC38A10,CNOT6L,CNPY3,UBE2M,IFT46,TMEM160,TSHZ1,ZFP64,DENND4C,DENND1B,WDR18,RPL8,ILF3,LRRC1,RHOT1,TSR2,MARK2,ECH1,PRDX1,PLD3,NUCB1,GNA12,FBXO21,C1orf131,PRDX3,PFDN4,HNRNPH3,STX18,TFDP1,KHSRP,ASNA1,CPEB2,SSSCA1,VPS29,BYSL,S100PBP,MIB2,IER2,PTMS,NOP2,UBN1,DCAF15,NF1,ALKBH5,MOGS,TAF6L,BECN1,MAPK14,SNAPC4,RNF103,BCAT2,MBD4,C18orf32,METTL14,ZNHIT6,IMPAD1,RCSD1,PHTF1,SRI,KIF22,ZBTB22,NFU1,OGG1,TRIM14,ELOF1,COPS8,FYTTD1,TRIM8,RRM2,SOX4,ABHD5,CXXC4,UBTF,PAF1,UEVLD,SPATA2,PQBP1,IARS2,ATXN2L,GALNT10,STARD3NL,RPS15,PIGN,AGTRAP,CIB1,XPO7,SRRT,ZNF449,CAPZA1,GLTP,BCL2,KIFAP3,N4BP2,HP1BP3,VOPP1,THNSL1,ISG15,CAND1,C22orf46,GNAS,TSC1,RBM25,CDCA5,ZFP90,NANP,RBBP4,ZBTB24,SMARCD1,MBD1,WASF2,MMACHC,TOMM20,IFI27L1,GNPNAT1,MPHOSPH8,HNRNPUL2,CHD1,MEAF6,C2orf68,CCDC50,AKAP8,PARL,RPN2,CHTOP,FAM3A,F2R,SCYL3,TMEM14C,ABI1,HTRA2,MOSPD1,RLIM,FAM172A,ZNF500,PSMB7,NLN,WIPF1,BOLA1,BUD13,NDUFB1,PEF1,EIF3G,BTBD1,TAB2,CHCHD1,TULP3,WDR59,CANT1,SCARB1,GAS2,USP11,SMURF1,TSPAN5,PPP2R2D,CDS2,MAGEH1,MRPL42,EYA1,CDK2AP2,MRPS26,LETMD1,KLF13,HDDC2,RGS1,MAN1A1,FBXO5,GART,PELO,TANK,BRD7,MRPL11,SAMD4B,ZDHHC18,GTF3C6,POLR3GL,WDR81,MEN1,ZNF407,MFN2,COX8A,ZRANB2,MBD6,SRSF3,ATP6V1C1,IDH3B,TATDN1,TSC2,LACTB2,CMTM6,RBM4,ZNF275,ANKRD39,RPL23A,CDKN2C,NAPG,USF1,DNAAF2,MECR,AP1M1,UPRT,CRY2,ECD,RNF26,TIPARP,LRRC59,ANKRD9,RHBDD2,MGAT5,BAK1,ZNF559,RHOBTB3,GABPA,WBP1,NUTF2,ARF4,GINS4,KRIT1,BOLA3,AHNAK,RAD18,PDRG1,RNASEL,CHPF2,OAZ1,SMNDC1,PDCD4,NXT2,HIVEP3,KIAA0100,CLSPN,RHOC,DHX9,PDCD7,PSMD9,HAUS2,COPB2,CD59,TFAP4,RNFT1,RIMS3,MEGF8,EFTUD2,FBXO7,CPSF4,MRPL21,PHKG2,LUC7L2,SRSF11,EIF3L,MTA2,TYW1,USP10,ITM2A,SSR2,BCLAF1,MTX1,SFXN5,FNTA,PDLIM1,TXNDC16,ZNF830,TMEM159,MRPL3,ALS2,FAM72A,TRIM41,KARS,NQO1,POC1A,ANK3,PTTG1,TPX2,TBC1D13,DAZAP2,STMN1,C19orf48,REPS1,CBWD5,ABHD16A,FBXL6,SH3BP1,MTA1,UBA5,CLCN6,INTS12,C8orf59,RPRD1B,CGGBP1,CPNE1,SEC61B,POLR2L,FAM118B,GOPC,E2F3,CIRBP,RPL38,CRNKL1,PFKFB3,GORAB,RAB1A,GIGYF1,TMEM184C,PPP2CA,KIF2A,CCDC14,LSM6,RNF38,SNRPG,DMWD,USP13,ZFP91,TRMT6,IP6K2,WDR5,SLC25A43,PMVK,IFT27,NEIL2,RRP36,SRXN1,RPA2,PSMD2,CLIC4,PDCD10,CBWD2,COQ4,ITGB8,ARF5,ARHGEF1,FBXL19,GTF2H2,TTPAL,UTP20,MAGT1,GPS2,DBI,SSNA1,MRFAP1L1,CD81,TMEM131,WDR13,FANCI,PAPOLA,CREM,FANCL,GLIS2,IL6ST,INTS1,POP7,SLC44A1,MTPN,ASB6,PLK1,RPP25,SEPT9,CELSR2,RBX1,APH1A,RAD51AP1,CKAP2L,PSMG1,UBE2V1,EAF2,IL12RB1,KRTCAP2,LUC7L,LSG1,NECAP2,C1orf122,TRIM4,AGPAT2,CHD3,ZNF367,E2F4,PRPF4,KPNA2,BEND6,CLN3,DNAJC30,NGLY1,POT1,MYL12B,CCDC137,RMND5A,HJURP,PHB2,DNAJB2,FAM53C,NKD2,SDC2,KLC1,CDK13,ADCK5,COX4I1,DNAJB1,RAB6A,ARID1B,C1GALT1,MLX,UBE2Q2,CCP110,ZNF746,ARL6IP1,CTR9,NIPSNAP1,ABHD2,DCAF8,ACSL3,LDB1,MAP4K3,ARMC8,NMT2,IRF5,RPL36,HAUS8,MBIP,ORMDL2,COX7A2L,ZDHHC7,SIL1,FAM122A,UNC13C,BCCIP,SART1,TRAF7,NDUFAF2,TOR1AIP1,ZNF416,LAGE3,TM9SF3,ZFYVE21,RRAGC,ZNF121,OIP5,NRF1,WDR44,PPME1,PIN1,EFCAB11,RPAP1,CABLES2,LMAN1,AHCYL1,TOP1MT,STRAP,SPSB3,ZNF583,SNX25,ARHGAP17,POLR2G,ZNF780B,PPT1,NUP155,DCLRE1C,MRPS14,RHBDF2,SUGP1,RBL1,FASTK,STK38,AP1S1,SPRYD4,H3F3A,CHID1,SMAD4,RAD51D,SLC30A9,UNK,CMAS,NADSYN1,HMGN3,NCAPG,SCYL2,FZD6,HERC3,GTPBP3,CTSS,ORC3,RNLS,YTHDC1,ACP2,HMGN5,CSRP1,METTL5,ABCF2,TUFM,RANGAP1,PNPLA8,HAGH,API5,ZFR,SEC23IP,E2F1,USP20,TMEM219,RBPJ,MAX,PDCD6IP,LUZP1,GXYLT1,ADAM10,CXXC1,TSC22D3,AP3M2,CUL1,GYG1,NANS,OAT,MYEF2,ANKRD26,PA2G4,NOL11,FIZ1,ZNF200,MARCH2,SLC26A2,SRP72,KLF10,LACTB,RFC2,CBFB,RAB2B,PRIM1,MAP3K4,HHEX,RPS14,LUC7L3,MAP4,MRPL27,BTF3,PTPDC1,CCDC59,NMD3,PTOV1,COX5B,DNAJC5,SCOC,DHPS,POLR2K,ANKH,VAV2,C16orf87,PRKAA1,GSPT2,DLGAP4,PXMP2,PRPF39,PSEN1,ZNF79,PDXDC1,VPS25,NDUFS7,YY1AP1,C12orf10,FAM192A,RPN1,LHX8,ARPC5,ZNRF2,DAPK1,TPST1,PIK3IP1,CYC1,SOCS5,FDFT1,PIGT,WDR1,EMB,ZNF574,C1orf35,EXOSC9,ARID1A,PTTG1IP,C9orf40,FXR1,GOSR1,MAP2K2,TWISTNB,AKAP1,XRCC5,HMGN2,PI4K2A,SEC31A,CAT,DERL1,HSPBP1,MTHFD2,CEBPG,ARAP1,FAM83D,USP32,CABIN1,SMPD4,GPI,CYTIP,TP53RK,REPS2,RAB11B,UROD,SLC39A13,POMP,BCL2L1,NUDT19,DECR1,RALB,SIAH1,ADCY9,LPIN2,SOCS6,MRPS27,TTC3,RNASEH2A,CFL1,ANKLE2,CDC123,OAF,VDAC2,EDF1,ERC1,EML4,ANKZF1,ZNF282,RAD51C,DSN1,DDOST,HINT1,DGCR8,SAFB,HAGHL,LMBR1,FTSJ1,RWDD4,NCLN,BEND3,EYA2,DYNC1LI2,B4GALT5,SLC41A1,MANBA,TKT,FAM76A,CBLL1,ARGLU1,LANCL1,POFUT1,FAM8A1,HEATR5B,HLA-A,EBP,RFWD3,NDUFA2,FUT8,FJX1,BTF3L4,PTPN11,MRPL54,FEM1B,RPL19,CNN2,NDUFA3,MTX2,MSH6,PDLIM2,LONRF3,RFXANK,FBXO9,GUF1,RPL32,ZHX1,NDUFS5,WDR91,GPR89B,HIGD2A,ZBED3,RORB,POLA2,ZNF76,COPA,UQCR10,HMGXB3,PHRF1,ABCB10,COMMD5,MAP1LC3B,DST,SIVA1,RAB35,GPATCH1,TCEA1,DRAM2,DEAF1,SNRNP200,NCK1,LAP3,VHL,SREK1,ARHGDIB,PITPNB,HSPB11,BRWD1,PPM1G,SH3GLB2,CRCP,BAZ1B,CAB39,ACBD4,STK11,CLU,CHEK2,ZSWIM3,TSTD2,CHPT1,MRPL13,DCAF5,CAPN1,UBE2D3,NSMCE4A,PPP1R12A,ZCCHC8,GORASP1,NACA,UBXN1,PCSK7,EPN1,RPL15,THRAP3,TTF1,QSOX2,NUP205,PRPF18,CHKA,DTL,MED10,ZRANB1,MCPH1,SLC12A2,ATP6V0D1,CSNK1G3,CREG1,NUDT4,RPL6,VKORC1,SLTM,EVC2,KLHL15,SIAH2,SLC16A1,EHD4,SNRNP70,C11orf1,APOL2,N4BP2L2,SNX27,CHMP2A,CORO7,UCK2,PMS2,UCK1,CLCC1,EXT2,MXD1,USP5,HNRNPA2B1,SAP130,NVL,PPP6C,CYB5R1,ZNF770,EBAG9,RNF25,PCGF6,METTL2A,FAM72B,PON2,HNRNPR,HPS5,STAT6,MAPK1,BRD9,TMEM33,NAT14,DNAJC2,TRIP12,SHPRH,SCYL1,VPS45,MYO9B,GFM2,SPPL2A,FASTKD3,FGFR3,MZT2A,PPIG,ZDHHC13,TMEM99,H2AFY,ATG13,NDUFS8,ERI3,FBL,FRMD8,SLC35A1,MICAL3,TGFB1,B3GALT6,ELOVL5,HEMK1,TIMMDC1,HELB,PSPC1,MIER1,SCFD2,NDRG3,CDK11A,MTMR3,ACAT1,CENPT,PLOD3,RAB3IL1,ZSWIM6,RAB14,ADD1,MRPS15,KDM4A,XIAP,DHX8,GLUD1,ANKRD23,PABPC4,CALM2,CDK5,PSMD1,NEK6,NSRP1,RABGAP1L,SRSF4,FNIP2,KCNAB2,PCBP2,MLST8,PLK3,ZNF672,MRPL43,HSDL1,TOPORS,MCL1,SMC2,PPFIA3,ICMT,SLC50A1,STOML2,LIMK1,ZNF689,PRDX5,ATE1,MLYCD,ATP6V0C,ST3GAL2,FBXL3,TFDP2,E2F2,PFKP,AAAS,DDX42,SSRP1,MRPL9,MRPS2,STRN4,TOP2B,ZNRF3,TMED3,DDRGK1,RAVER2,GNS,INTS7,INPP5A,MCM5,PHF14,ZNF326,UBE2QL1,NAGPA,TIMM8B,ETV3,TSPYL4,DHX29,TEX10,MAN1B1,RPS10,CBFA2T2,ABCF1,RHOB,LRRC14B,DTWD1,PTPRF,SCARB2,OSBPL11,CCDC86,DUSP3,SLAIN1,MDH1,HEXA,RNF139,SNX14,ZNF296,TRERF1,UBR2,CHD1L,ACTR3,WDTC1,MYH9,CREBL2,NIPA2,PRKACA,SAFB2,ANKIB1,STAM,ARL6IP6,RAB21,SP100,ZKSCAN1,DDA1,NUP107,ANKRD13C,MAVS,CEP63,TMEM136,RBM15,ATF2,DCTN1,SHOC2,PSRC1,MAP4K4,WBP2,ATP6V0A1,DNAJA1,NDUFA7,TAZ,C19orf54,TAF2,SEC61A1,WDR7,RPLP1,CBLN2,RBMS1,FUS,GEN1,LRP8,COIL,LRCH1,GALK1,ZNF786,RPS2,SESTD1,TRAK1,JMJD6,SIKE1,AKT1S1,KRI1,FBXO3,ERH,PPP1R8,PRDM4,GTSE1,GEMIN6,DCP1A,SGCB,S100A6,IMPA2,NUDC,PDPK1,TK1,GUK1,TNFAIP3,GALC,ZNF512,KIAA0930,MRPS10,DDX39A,RPA1,ZNF862,ZNF180,KEAP1,POLE,TATDN2,PITX1,CAPN7,LRPPRC,PML,HMGB2,USF2,ANAPC4,SRM,DDX47,MCCC1,CDC42SE2,S1PR2,CDIPT,SEC16A,SSR1,LIN9,PCNA,ZNF639,PIK3R2,ETV6,TXLNA,PPCDC,FAM86C1,MYBL1,MRPL32,CCAR1,ABCC5,PBXIP1,BAZ2A,TLK1,MRPL12,EZR,LNX2,LRP5,BRCA1,PRKRA,STX16,EPB41,OPTN,SEPT1,SOCS4,QRSL1,PIEZO1,GLCCI1,NUDT11,NAA60,GEMIN7,SEPHS2,LZTR1,RACGAP1,PPP3CB,B4GALT4,RLF,RAPGEF6,SNRNP25,RB1,VASP,MED8,VMP1,PPIL2,MEA1,TIMELESS,AHDC1,ALDH18A1,TMEM8A,ABCC1,PREB,TRAPPC9,AACS,MEMO1,KRAS,RTF1,UBE4B,NFATC2IP,LY6E,ARPC1A,ZNF174,PSMC4,GOLGA4,SYNCRIP,PALB2,PRPS2,NIPA1,TIGD2,RNF114,FOXM1,MRPL39,XAB2,SUMO2,DUSP22,COMMD8,RPL11,CSDE1,MDM2,CORO1A,MINPP1,METTL9,POC5,DVL2,GM2A,PSMA8,COQ10B,CPOX,TIGD5,SLC26A6,CYP20A1,PRPF3,TXNL4A,RPSA,SRSF1,DNAJC10,ZNF700,SCAP,PLEKHG4B,TIMM17A,FAU,LTA4H,AP2S1,USP53,INTS2,CTDP1,MIF4GD,CDT1,ARID5A,SUMF1,GGA2,AP3S1,CSNK1A1,RMI1,TFRC,PTPN2,IRF4,STARD9,GSTK1,NDUFV1,SLC1A4,CWC27,SLC35B4,DDX31,ABCD1,RPAP3,CNTN5,SNX2,ZMYM5,CCDC34,CHCHD6,BSDC1,KPNA4,CDKN2AIPNL,FBXO41,BIRC5,TFE3,SNAP29,CDCA7L,PKD2,ACADM,CHMP7,SAT2,GCSH,ZNF496,TMEM109,TAP1,YTHDF3,NHLRC3,IKBIP,EIF1B,ELMOD2,KIFC1,DBNDD1,RNASEK,CDC25B,PRADC1,DNMT1,NOL12,ORAI2,USO1,AKT2,GNG7,AURKB,MCFD2,SLC25A5,ZFAND5,MAK16,STT3A,TMED10,PSMD8,EIF2D,ITGB1,PTPN7,UQCRH,RRS1,ARRB2,RTN3,ZNF598,SVIP,DDX58,WSB2,PPIB,MUT,GMFG,HLA-E,NDUFA4,MAN2B1,METTL3,CFLAR,NDUFS4,RNF121,MEX3C,KLF16,HDAC7,DAD1,BDH1,PCYT2,GNAI2,ANKHD1,MORC3,TERF2,KCTD20,SEPT8,DCTD,TOMM40,PATL1,ADSS,SERTAD2,SERF2,ZFP92,NSF,DCK,ERGIC3,ACLY,LPCAT4,VCPIP1,YY1,PPP6R2,MAP3K5,PPP6R3,RNF14,CDK2,ZC3HAV1,ZBTB37,URB2,EIF3D,MAGED1,KLHL18,ADPGK,SLC25A44,AP1B1,SDHA,PAIP2,PHC2,CRKL,MOAP1,TERF2IP,CYHR1,ZNF75D,SHC1,UCHL5,NAA35,TMBIM1,CCT2,CDKN2AIP,MKLN1,HMGN4,GALK2,CDC23,SHCBP1,AP4E1,PRDM11,VEZF1,PPP2R5A,ACYP1,STAT1,PPA2,TRIM32,RHEBL1,C1orf112,TCF3,MRI1,BRAP,AGPAT3,MYNN,SDF2L1,SPR,RAB11A,REEP5,FOXO3,MAD2L2,CCDC28A,PIP5K1C,RBM17,MAT2B,PTEN,CENPJ,TAGLN2,OSTC,CREB1,PACS2,NCOA2,SMC4,RNASEH2C,NEK7,NET1,PARP4,TBRG4,ANAPC2,RPL27A,YIF1A,SGSH,HGS,TTLL4,SLC38A7,MFAP1,CCDC69,BRWD3,ESYT2,SKA3,NPHP4,UBE2E2,HNRNPAB,PLXNC1,ST13,TMEM184B,DNAJC24,ZNF107,KIF2C,SLC29A1,AGFG1,SIRT2,FKBP2,USP48,UBQLN2,SNRPD3,CUTC,EDC3,UBLCP1,ZNF804A,RAP1A,THADA,EIF4A3,AP3S2,ATG3,DPYSL2,PPP1R12C,AKR1B1,NDUFB9,JOSD1,RP2,TTC4,TECR,ARID4A,FGFR1OP2,TIMM50,TDP1,DPM1,FOPNL,SLC16A7,WDR82,SLC25A22,STK17B,DHX15,CHAF1A,GEMIN5,COPS6,SASS6,RPS26,PSMC1,SLC12A7,TBC1D12,TM9SF4,ZNF768,UFC1,MED13L,TIA1,EPHX2,PITHD1,RHBDD1,NFATC3,BANF1,ZNF335,BUD31,YBX1,KNTC1,ACAD8,UBE3C,ZNF189,ALDH9A1,KDELR1,TSTA3,CIC,OXR1,PSMA1,SEPT7,NAP1L1,ODF2,EXOC4,KIAA1328,NUP62,PITPNA,NAA20,PTDSS1,MZT2B,PDSS2,C7orf26,TMEM106C,IMMT,ASH1L,CHERP,WDYHV1,PLAGL2,CHKB,IRF3,TWF2,PAIP1,ANKRD28,ANKLE1,FARSA,SAR1A,SCAMP4,APOOL,PDIA6,ACSL5,TOR1AIP2,AZI2,GFER,RAD54B,TMEM41A,DAP3,ZNF317,GADD45B,AKNA,REEP4,CBX4,MIF,KIF3B,GOLPH3L,SH2D3A,CASP6,TOR3A,SRGN,DBF4,MFSD10,SAC3D1,CTNNBL1,YIF1B,CLDND1,TTC17,SLC25A1,GINS1,PAQR6,CSNK1G2,TELO2,ADAM17,HMGN1,NASP,ASPM,PRKAR1B,SYMPK,TARS,SNRPA,MAPK3,HSPA1B,HLA-B,ATAD2,PLAA,ZNF330,OSBPL8,KBTBD7,PREPL |
| 1.898e-10 | -22.38 | GSE22229_RENAL_TRANSPLANT_VS_HEALTHY_PBMC_UP | MSigDB lists | GSE22229_RENAL_TRANSPLANT_VS_HEALTHY_PBMC_UP | 179 | 61 | 17377 | 2626 |
UBE2D3,HIVEP3,CYTIP,KARS,TRIM11,VAV2,PTTG1,CDK2AP2,CERK,NUF2,GGA2,SNN,ETS1,TCF19,SPAG5,FANCL,CDKN2C,RAB8A,CCNA2,EIF4A3,MBD2,RCSD1,TPST1,PDS5B,GEMIN6,GTSE1,CDC25B,ARL5A,TACC3,SMC4,SNX25,TTPAL,TDP1,TK1,NXT1,TNFAIP3,BTG2,KIAA0930,MKI67,KRAS,EXOSC9,RAB3IP,LY6E,IRF5,SUPT16H,SH3BP5,RAD51C,KPNA1,TXNDC16,CSK,ARNTL,MEGF9,SLC16A1,KLHDC4,MAP3K5,NDE1,BRD9,UBE2C,PSMC1,LRCH1,TMEM131 |
| 1.960e-10 | -22.35 | GO_NUCLEAR_CHROMOSOME_SEGREGATION | MSigDB lists | GO_NUCLEAR_CHROMOSOME_SEGREGATION | 205 | 67 | 17377 | 2626 |
ZNF207,CHMP2A,PDCD6IP,ACTR3,PTTG1,NUF2,KIF2C,CCNB1,BECN1,MIS12,KIFC1,AHCTF1,KIF14,AKAP8,NUP107,PDS5B,KIF22,MCMBP,SEH1L,PLK1,PSRC1,TAOK1,CUL3,NUSAP1,AURKB,SMC2,CDC23,CHMP2B,KIF2A,RAD51C,CHMP4A,KIF18B,DSN1,CEP55,CHMP4B,VPS4A,RRS1,MAPRE1,PHB2,CENPF,CDCA8,KIF23,TOP2B,RACGAP1,PMF1,NCAPG,RAB11A,SPAG5,RB1,SMC3,NAA50,PRC1,CENPM,KNTC1,NUP85,NUDC,SMC4,RANGAP1,KIF18A,BIRC5,CDCA5,FAM83D,CENPT,NDE1,CHMP7,TERF1,ESPL1 |
| 1.961e-10 | -22.35 | transcription, DNA-templated | biological process | GO:0006351 | 2600 | 504 | 17256 | 2622 |
ZBTB10,TXN,ZNF496,MAX,KDM4A,CXXC1,CCNL2,CCNB1,COMMD6,EDRF1,POLR3K,MYEF2,ZNF275,PA2G4,USF1,CIPC,NOL11,FIZ1,SRSF4,ZNF200,CRY2,TAF5L,ECD,ZNRD1,DNMT1,ZNF800,CDC5L,ZNF524,ZNF672,ZNF559,KLF10,GABPA,ELOA,MIER2,TOPORS,USP22,DIDO1,CBFB,IWS1,BRMS1,HHEX,SMAD2,BRD2,ZNF689,VIPAS39,BTF3,TFDP2,SMAD1,ARRB2,E2F2,ZNF75A,CCDC59,HDAC2,SLC25A33,PTOV1,SSRP1,HIVEP3,EWSR1,POLR2K,PRKAA1,DHX9,EZH1,PMF1,NOTCH2,SUPT7L,ZNF79,ZNF518A,VPS25,CDC73,YY1AP1,CNOT3,MCTS1,TFAP4,LHX8,INTS7,KLF16,HDAC7,ZNF326,FOXN2,CPSF4,EEF1D,SRSF11,PHF10,ZNF84,ETV3,FOXK1,ELL2,RB1CC1,ZMYND11,ZNF574,MYBL2,BCLAF1,ARID1A,SRSF5,CBFA2T2,ELK1,KDM3A,PHF6,TWISTNB,XRCC5,ZNF777,SERTAD2,POLR2J,ETS2,ZFP92,SETD3,RBMX,MED15,PIAS2,CEBPG,CNOT6,YY1,RNF14,NRBP1,SGF29,ZNF511,ZNF296,SARNP,ATXN3,TRERF1,IVNS1ABP,ZBTB37,SUZ12,PTTG1,CREBL2,ZNF267,INO80E,SAFB2,RCOR3,TCF19,TERF2IP,SPINDOC,ZNF420,ZNF75D,SP100,KDM2A,ZKSCAN1,MTA1,UCHL5,GMEB1,LPIN2,NABP1,INTS12,ZNF226,ATF2,RPRD1B,CDK12,CGGBP1,SAP30,CPNE1,BRD4,POLR2L,EID1,ERF,KAT7,DRAP1,INTS13,WBP2,POLR2D,RNPS1,E2F3,SLBP,ELP4,EDF1,MEF2D,TRIM28,CENPU,PRDM11,SUPT16H,DDX17,TAF2,CHCHD3,VEZF1,ZNF282,HINT1,SAFB,HIPK2,STAT1,ATF6,SNRPG,BEND3,PPP5C,ZBTB11,EYA2,ATMIN,POU3F2,COMMD10,NCOR2,ZNF786,ZNF445,DEPDC1,SRSF6,MECP2,TWNK,TCF3,HABP4,JMJD6,ARGLU1,MYNN,WDR5,ETS1,HMG20A,FOXO3,MAD2L2,NEXMIF,ZNF92,WWP2,GTF2F1,CCNK,ZBTB45,SUV39H2,ELP5,PPP1R8,ZNF260,PRDM4,CARF,CITED2,CNOT6L,ZNF710,CREB1,GTF2H2,MED22,NCOA2,TSHZ1,PDPK1,ZFP64,KAT2A,ZNF512,RFXANK,ILF3,DDX39A,COMMD4,KLF6,POLR2A,CBX3,ZNF862,ZNF180,KEAP1,ZHX1,PITX1,TFDP1,LRPPRC,PML,KHSRP,DDX5,HMGB2,USF2,TAF6,PURA,THAP5,RORB,CCNC,ZNF76,IER2,THOC1,GPBP1L1,KMT2E,PHRF1,RBM8A,CSNK2A1,ZNF107,TAF6L,SND1,SIRT2,SNRPD3,COMMD5,MAPK14,SNAPC4,BIRC2,ZNF696,PAPOLA,CREM,LIN9,GLIS2,EIF4A3,ZNF639,INTS1,JAZF1,ETV6,PHTF1,NOC2L,ZBTB22,TCEA1,MYBL1,ARID4A,CARM1,CCAR1,RYBP,ELOF1,SP3,DEAF1,BAZ2A,SNRPB,RIOX2,MRPL12,PBRM1,BRCA1,EAF2,KMT2C,SOX4,USP21,ASF1B,PAF1,UBTF,BRWD1,CHD3,E2F4,ZNF367,PQBP1,CRCP,BAZ1B,ZNF268,CHEK2,DVL1,ZNF45,BEND6,FAM208A,ZNF564,FUBP1,ZCCHC9,PHB2,ZNF768,NACA,CTCF,CHCHD2,MED13L,MEF2A,CDK13,THRAP3,RLF,ASXL2,CNOT11,TTF1,SRRT,ARID1B,LYAR,SUB1,RB1,MLX,NFATC3,MED8,ZNF449,MED10,MBD2,SSBP3,ZNF746,ZNF335,BUD31,CTR9,TIMELESS,MDFIC,ICE2,YBX1,MAML1,ACAD8,PREB,ZNF189,VOPP1,POLR2I,CIC,LDB1,UTP15,RTF1,ZNF761,SLTM,DAPK3,IRF5,ZNF174,RXRB,NFIL3,TBPL1,PRMT7,NUP62,ZFP90,RUVBL2,RBBP4,HNRNPDL,ZBTB24,ADNP2,TCF12,MBD1,ASH1L,TRAF7,MPHOSPH8,ARID2,FOXM1,DYNLL1,XAB2,ZNF416,SMARCA4,RRAGC,PLAGL2,NSD3,IRF3,CHD1,ZNF121,COMMD8,MEAF6,MXD1,SAP130,RRN3,NRF1,ZBTB21,ZNF473,KMT5C,ZNF302,CD3EAP,AKAP8,RPAP1,TARDBP,CHTOP,UTP4,SAP30L,ZNF770,DVL2,ZNF583,RLIM,CSTF1,KDM3B,POU2AF1,POLR2G,ZNF780B,ZNF500,BTG2,PCGF6,ATXN1,NFATC2,KDM1B,MBD3,SRSF1,ZNF317,RBL1,ZNF700,MAFK,STAT6,ARNTL,ZNF436,DNAJC17,NCOA1,AKNA,MAPK1,BRD9,SMAD4,CBX4,INTS2,NAT14,SLC30A9,DNAJC2,CTDP1,NIFK,CDC40,MTERF1,ZNF316,EYA1,SCYL1,AGO2,ARID5A,KLF13,PAWR,GTF3A,NKRF,MXD4,PAGR1,IRF4,KMT5A,NABP2,BRD7,ANP32A,SS18L1,POLR1B,STAT3,RBM15B,SAMD4B,GTF3C6,RPRD1A,HMGN5,PSPC1,ZNF202,MIER1,ZMYM5,RCOR1,POLR3GL,PCGF1,MEN1,ZNF407,SYMPK,MAPK3,TFEB,CNOT9,ATAD2,BIRC5,L3MBTL3,TFE3,CDCA7L,BBX,E2F1,KMT2B,RBPJ,SRSF3,TAF12,NR2F2,ZMIZ1,HIPK3,IFI16 |
| 2.015e-10 | -22.33 | centrosome | cellular component | GO:0005813 | 488 | 125 | 18223 | 2701 |
BCCIP,FGFR1OP,NPHP4,CYLD,DYNLL1,POC1A,OLA1,NIT2,CNTROB,KIF2C,BCL2L1,SIRT2,CCNB1,PRKACA,CALM2,ANKRD26,CLUAP1,RAB8A,PCNA,NEK6,CDC42,ABRAXAS2,XRCC2,DNM2,RNF19A,CDC25B,CEP63,SPATC1L,RPRD1B,POC5,DCTN1,PLK1,PLK3,FOPNL,KIF15,TUBGCP5,CKAP2L,BICD2,AURKB,CCNF,KIF2A,HSPB11,CDC16,RAD18,PPP2R5A,CHD3,CCDC14,CEP55,H2AFX,VPS4A,AKNA,GEN1,SLF1,TRAF5,SASS6,SMAD4,AAAS,CSNK1D,DYNC1LI2,RAD51D,CTDP1,KIF3B,MAPRE1,MZT1,PPP1R12A,MECP2,CENPF,DCTN2,DHX9,FLOT1,RAB23,CIB1,KIF23,HAUS4,CSNK1A1,IFT27,PSEN1,RAB11A,HAUS2,TUBGCP2,RAPGEF6,SPAG5,DTL,MZT2A,CLIC4,CCP110,SLC1A4,CENPJ,AXIN2,KIFAP3,FBXL7,GNAI2,ATP6V0D1,IFT46,KAT2A,TCTEX1D2,ASPM,JTB,PSMA1,CCT8,SPPL2B,HSPA1B,MASTL,HAUS8,ATP6V1D,PCM1,NEK1,CDC27,SNAP29,ODF2,E2F1,NLRC5,USP20,SLC16A1,NUP62,SSNA1,RUVBL2,NDE1,WDR62,CCNB2,ECPAS,CDK2,ESPL1,MZT2B,ALS2 |
| 2.039e-10 | -22.31 | MORI_LARGE_PRE_BII_LYMPHOCYTE_UP | MSigDB lists | MORI_LARGE_PRE_BII_LYMPHOCYTE_UP | 84 | 37 | 17377 | 2626 |
TXN,HNRNPAB,CDCA3,RRM1,KIF23,SMARCA4,RACGAP1,SLC29A1,CCNB1,STMN1,DTL,CDKN2C,CCNA2,MCM5,DUT,PRC1,KIF22,SMC4,MYBL2,MKI67,SLBP,RRM2,RANGAP1,SMC2,MCM2,H2AFV,ASF1B,HMGN2,IDE,CDCA5,H2AFX,ANP32E,KPNA2,RBBP4,CCNB2,PSMC1,TUBB |
| 2.116e-10 | -22.28 | CCNB1 (cyclin B1) | protein interactions | 891 | 145 | 55 | 17029 | 2761 |
FOXM1,CDT1,GADD45G,ZADH2,CDK5,RB1,PCNA,PSMA6,PIN1,PRC1,CDKN1B,KIF22,CDC25B,UBE3C,DNMT1,ARID4A,CCAR1,DCTN1,CDC5L,PLK1,STAU1,RHOBTB3,RNASEH2C,PRKDC,PBK,E2F3,CDC6,BCLAF1,BRCA1,USP22,PKMYT1,FXR1,CCNF,TRIM28,PRDX1,RPA1,CAND1,TSC1,KEAP1,CDC16,PDCD6,PCM1,CDC27,CCDC6,PRDX3,STK38,GADD45B,MAP4,UHRF2,PTPDC1,CDK2,CCNB2,ESPL1,ANAPC4,ZC3HC1 |
| 2.117e-10 | -22.28 | GO_CELLULAR_CATABOLIC_PROCESS | MSigDB lists | GO_CELLULAR_CATABOLIC_PROCESS | 1272 | 273 | 17377 | 2626 |
PDCD6IP,HEXB,CUL1,GLUD1,GYG1,OAT,CCNB1,UBE2I,PARK7,PABPC4,FBXO22,RPL23A,CDK5,CALM2,PSMD1,RAD23B,PCBP2,USP34,TOPORS,AURKB,AMDHD2,USP22,CCNF,RPS27A,PSMD8,RPS14,AXIN1,PRDX5,MLYCD,ATE1,SMG9,FBXL3,ARRB2,LONP2,MUT,GSPT2,ADO,KCTD17,ZNRF3,PSMD9,PARN,VPS25,NPLOC4,CNOT3,GNS,RNF121,PDXP,EXOSC7,BDH1,FBXO7,FBXL7,PHKG2,PABPC1,MAN1B1,RPS10,USP10,RPS24,EXOSC9,MPG,PATL1,PSMB3,CAT,DERL1,KPNA1,USP32,CNOT6,GPI,SMPD4,RNF14,HEXA,RNF139,NUDT3,ATXN3,UBR2,PTTG1,ANKIB1,NUDT19,DECR1,SIAH1,UCHL5,MTA1,DUT,LPIN2,SOCS6,NSFL1C,TTC3,ANAPC7,RNASEH2A,RNF19A,CLN6,ENPP4,SEC61B,RPL38,POLR2D,RNPS1,CUL3,CDC23,PSMB9,ANKZF1,PPP2CA,ALDH3B1,CDC16,HINT1,LSM6,RPLP1,RNF38,SEL1L,TRIM32,USP13,RPS2,SDF2L1,UBE4A,NEIL2,WWP2,CAPN2,PSMD2,HUWE1,RPL17,PPP1R8,CRAT,GTSE1,DCP1A,RPL19,UPF2,UBE3B,CNOT6L,FBXL19,TNFAIP3,RNASEH2C,GALC,USP42,RPL8,FBXO9,ANAPC2,RPL27A,PDE3B,SH3GLB1,ECH1,PRDX1,FBXO21,KEAP1,RPL32,PRDX3,TATDN2,ACOX1,PML,KHSRP,HMGB2,ANAPC4,DDB1,FAF1,RBM8A,MCCC1,UBE2Z,SIRT2,USP48,UBQLN2,BECN1,BIRC2,RNF103,EDC3,PCYOX1L,BCAT2,MBD4,EIF4A3,GOT2,HADHB,OGG1,PLK1,EXOSC6,RBX1,USP21,RPL37,VPS4A,CHEK2,NGLY1,RPS26,PSMC1,CAPN1,UBE2D3,RPS15,TMUB1,DNAJB2,UBXN1,RPL15,THRAP3,EPHX2,PRPF18,DTL,SLC27A4,AHCY,UBE3C,ACAD8,ZRANB1,ABHD2,ERLIN1,GBA,RPL6,PSMA1,SYVN1,UBE4B,ISG15,RPL36,PSMC4,CDC27,KLHL15,SIAH2,CTSA,DTD1,USP7,CYLD,RPLP2,PAIP1,RAD23A,USP5,RPL11,CSDE1,UBXN2A,PSMA6,MDM2,KIF14,EXOSC1,HTRA2,GM2A,RLIM,PRPF19,SNX25,RPL29,RPL35,POLR2G,PPT1,PSMA8,RAB7A,PSMB7,OGDH,EDEM2,RPS9,USP36,RPSA,PON2,DNAJC10,IDE,PSMD3,UBXN2B,ARNTL,UHRF2,CHMP4B,USP11,FAU,SMURF1,LTA4H,TRIP12,KLHL21,CSNK1A1,DNAJB9,HERC3,CTSS,KLHL20,PELO,ABCD1,RNF5,TGFB1,RFFL,PNPLA8,HAGH,NEU1,UPF1,USP20,ACAT1,ACADM,TATDN1,UBE2C,GCSH |
| 2.125e-10 | -22.27 | GSE6674_UNSTIM_VS_ANTI_IGM_AND_CPG_STIM_BCELL_DN | MSigDB lists | GSE6674_UNSTIM_VS_ANTI_IGM_AND_CPG_STIM_BCELL_DN | 188 | 63 | 17377 | 2626 |
WSB2,SRM,FAM208B,PPP1R12A,NOP2,URB2,SRSF6,GADD45G,C5orf30,INO80E,BRIX1,C19orf48,SLC20A1,ANKIB1,QSOX2,MRPL19,KRI1,IRF4,RRN3,AHCTF1,EIF4A3,UTP18,ETV6,UBA5,AKAP8,ZCCHC2,EXOSC1,TXLNA,ZDHHC13,MDFIC,GEMIN4,PIKFYVE,PPA1,LYPLA2,PLK3,B3GALT6,PPAN,USO1,AGGF1,SEPT9,LAP3,TMEM39A,C16orf72,NSUN2,E2F3,GTPBP4,UTP15,ADSL,ODC1,MAK16,PICALM,TARS,MAT2A,NIP7,MAFK,TFDP1,SIAH2,AEN,RRS1,PDCD11,LRP8,NMD3,BYSL |
| 2.125e-10 | -22.27 | GSE1460_INTRATHYMIC_T_PROGENITOR_VS_NAIVE_CD4_TCELL_ADULT_BLOOD_UP | MSigDB lists | GSE1460_INTRATHYMIC_T_PROGENITOR_VS_NAIVE_CD4_TCELL_ADULT_BLOOD_UP | 188 | 63 | 17377 | 2626 |
TCF12,HNRNPAB,FOXM1,NF1,TMEM97,RRM1,CSNK2A1,SMARCA4,PXMP2,BLM,FANCI,FBXO5,PTPN2,OIP5,FANCL,PA2G4,CCNA2,SLC1A4,EIF4A3,ATIC,POP7,PPP4R1,NUP107,ANP32A,CENPM,IMPA2,MSH6,SMC4,WDR41,TIMP2,IDH3A,NSDHL,PBK,ABCF2,LDHA,MKI67,WDHD1,CDC6,EAF2,GALNT7,ICMT,SOX4,API5,CHAF1A,ZMYM3,CBX3,CHCHD3,RAD51C,ZNF282,PEX5,KIF18B,PRDX3,CCDC6,RBMX,TFDP1,PIAS2,PGRMC1,PKD2,PSAP,TFDP2,UBE2C,DDB1,HDAC2 |
| 2.130e-10 | -22.27 | FOXA1 (forkhead box A1) | protein interactions | 3169 | 286 | 89 | 17029 | 2761 |
DDX47,CORO7,FAM207A,URB2,HNRNPUL2,ALKBH5,RCOR3,RBM4,UTP25,CMSS1,NOL11,UTP18,CD3EAP,EXOSC1,SEPT11,NUP153,TARDBP,DNMT1,EXOSC6,AATF,KAT7,NOL8,NSUN2,CIRBP,EZR,DNAJC9,PRPF3,DNAJA1,KMT2C,LUC7L,GAR1,USP36,UBTF,C11orf98,CHD3,NIP7,SAFB,TBL3,H2AFX,CCDC59,SSRP1,DDX42,CCDC137,RECQL,RRP15,SRSF6,ZFP91,KIF23,RACGAP1,NKRF,DNAJB1,WDR5,CSNK1A1,PARN,PNO1,RRP36,MCTS1,RBM17,KRI1,TFAP4,RPA2,DDX56,PSMD2,HDAC7,RBM34,H2AFY,DDX31,OSTF1,CREB1,LUC7L2,EIF5A,STAU1,DDX24,TEX10,LDB1,ARMT1,EXOSC9,PHF6,UTP20,KPNA4,RPL32,RBM25,ODF2,KBTBD7,GPI,NR2F2,RBBP4,GPATCH4,DDX52 |
| 2.136e-10 | -22.27 | WONG_MITOCHONDRIA_GENE_MODULE | MSigDB lists | WONG_MITOCHONDRIA_GENE_MODULE | 201 | 66 | 17377 | 2626 |
NDUFA5,KARS,NDUFB6,SUCLG1,NQO1,MRPS15,UQCR10,GLUD1,DECR1,GOT2,TIMM23,DUT,ATP13A3,NDUFB9,MRPL32,GPX4,ATP6V1G1,PPIF,MRPL12,VDAC2,SLC25A22,NDUFA7,NDUFB1,PDHX,DAP3,TIMM13,PRDX5,MRPL27,COX5A,MRPL13,SLC25A39,COX5B,NDUFV2,MRPL42,SEC61G,COX4I1,NDUFA4,NDUFS4,NDUFV1,NDUFB4,CRAT,NDUFS8,BCL2,MRPL40,CYC1,MRPL11,NDUFA3,MTX2,NIPSNAP1,SLC25A1,TIMM8B,TUFM,TOMM40,SFXN5,CYB5A,SDHB,MTHFD2,ATP6V1D,COX7A2L,COX8A,LRPPRC,ACAT1,SLC25A19,NDUFS5,ATP6V1C1,MRPL3 |
| 2.144e-10 | -22.26 | localization | biological process | GO:0051179 | 5343 | 950 | 17256 | 2622 |
CCDC93,TMED7,RAB14,FGFR1OP,TSC2,ADD1,ABCC10,HEXB,TGOLN2,SYNRG,CMTM6,FBXO22,MIS12,RPL23A,CDK5,NAPG,PSMD1,RABGAP1L,DNAAF2,SRSF4,ATP13A3,AP1M1,DNM2,UPRT,NUP153,RNF26,KCNAB2,BAK1,PGAP2,RHOBTB3,TMEM115,NRAS,KIF15,MCL1,TOPORS,PPFIA3,NUTF2,ICMT,RAB22A,SLC50A1,ARF4,PLEKHF2,STOML2,MID1IP1,SMAD2,RPS27A,LIMK1,MYO18A,COX5A,VIPAS39,ATP6V0C,TFDP2,LONP2,AAAS,ANXA11,SLC25A33,DDX42,NXT2,GGA1,SEC61G,CCZ1,RHOC,CUTA,DHX9,RAB23,TOP2B,HAUS4,SLC4A2,TMED3,PSMD9,HAUS2,LMNA,COPB2,ATG4A,TMEM179B,GNS,CD59,EIF2S2,SLC38A5,MEGF8,RIMS3,FBXO7,TNPO3,GEMIN4,CPSF4,MVP,NUP85,PPP6R1,SRSF11,NAGPA,CYFIP1,TIMM8B,MAPKAPK3,ERO1A,RPS10,SSR2,SRSF5,MTX1,SFXN5,ABCF1,RHOB,CYB5A,MAGED2,PTPRF,SCARB2,OSBPL11,FNTA,KPNA1,WIPI2,NDE1,SGF29,SNX14,NUP58,ALS2,RHOG,EXOC3,ANKRD27,ABCA3,SARNP,ACTR3,ANK3,C5orf30,VTI1A,STARD7,MON1B,MYH9,TBC1D13,NUF2,NIPA2,NIT2,SLC35B2,PRKACA,STAM,CPNE3,REPS1,APP,KIAA1147,CLUAP1,RAB21,AHCTF1,ATP2A2,SP100,SH3BP1,TBC1D22A,TBC1D14,NUP107,CLCN6,SEPT11,MICU2,ANKRD13C,CEP63,ATF2,ZC3H3,ARL5A,DCTN1,ATP6V1G1,SNX8,ENPP4,CPNE1,SEC61B,PSRC1,GOPC,INTS13,WBP2,RPL38,POLR2D,RNPS1,ATP6V0A1,HTATIP2,NUSAP1,DNAJA1,RAB1A,KIF2A,ALDH3B1,PEX5,SEC61A1,VPS26B,CCDC14,CORO1C,RPLP1,PDXK,SNRPG,PITRM1,LRP8,TUBB,RPS2,MZT1,ANXA6,SRSF6,HABP4,FLOT1,TRAK1,BTN3A1,JMJD6,ATP5F1B,IP6K2,ETS1,IFT27,SLC25A43,WRB,SAPCD2,RPA2,PSMD2,PDCD10,ADD3,CLIC4,HUWE1,ARF5,DCP1A,ANXA5,GEMIN6,GTF2H2,TPCN1,S100A6,SPTAN1,PDPK1,PPP3CA,TNFAIP3,GUK1,MRS2,HEBP2,MTMR12,RAB3IP,DDX39A,PICALM,RPA1,SLC19A1,KIF18A,KEAP1,MAGT1,FAM3C,LRPPRC,PML,LY75,SLC25A19,HMGB2,SSNA1,PSAP,CD81,USF2,YWHAH,WDR45B,FAF1,SNAPIN,COX15,AGRN,THOC1,SNX15,RBM8A,CDC42SE2,SEC16A,RUFY1,GIT2,KCMF1,SSR1,DLG5,RAB8A,NUP210,TIMM23,PIK3R2,SLC44A1,TXLNA,ZFYVE27,ABCC5,VPS13B,CDC37,PTPRK,PLK1,SEPT9,MIOS,SNRPB,TLK1,CYSTM1,EZR,LRP5,ESYT1,ANLN,STX16,RAB5B,LSG1,OPTN,NECAP2,TRAM2,SEPT1,TBC1D17,TIMM13,AGPAT2,TONSL,GRIPAP1,ADAM9,ARRDC1,KPNA2,ACTB,PIEZO1,DVL1,CLN3,POT1,C2CD5,GEMIN7,PHB2,CENPF,NKD2,LAMTOR3,SDC2,CTCF,KLC1,ASAH1,COX4I1,RACGAP1,CDK13,RAB6A,NCKAP1,PPP3CB,RAPGEF6,RB1,TNS3,CCP110,RINL,VMP1,KIF13B,XPA,PPIL2,ARL6IP1,SLC27A4,GLE1,LRSAM1,PREB,ABCC1,CYTH1,TRAPPC9,ACSL3,KRAS,EIF2AK1,ARPC1A,ARMC8,APPL1,NPIPA1,ZDHHC3,NMT2,BBS12,PSMC4,HAUS8,RPL36,GOLGA4,PCM1,SNAP23,COX7A2L,LAMTOR4,ZDHHC7,SIL1,RUVBL2,ATP5F1A,UNC13C,NIPA1,RPLP2,DYNLL1,TOR1AIP1,COPE,SLC2A1,ZFYVE21,RRAGC,ATP6V1B2,LYN,BCAP31,RPAIN,RPL11,VAV1,ATP6V0B,PSMA6,MDM2,BRPF3,BCAP29,CORO1A,LMAN1,AHCYL1,GM2A,DVL2,PRPF19,SNX25,SLC39A9,PPIF,ARHGAP17,RPL29,CLCN3,TIMP2,RPL35,PPT1,PSMA8,RAB7A,PPIE,SLC26A6,MTMR6,NUP155,NFATC2,CHMP2B,VDAC1,ARL5B,RHBDF2,TMEM201,RPSA,SRSF1,ATP1A1,PSMD3,TIMM17A,TOMM6,CEP55,DNAJC17,AP1S1,CHMP4B,NCOA1,SLC22A23,LTA4H,AP2S1,CHID1,SLC25A39,PARD3,SLC30A9,UNK,SMAP1,CDC40,KLHL21,PDAP1,CDT1,TMX3,CDCA8,ARFIP2,ARF1,SLC12A9,GGA2,CSNK1A1,AP3S1,SCYL2,TFRC,CTSS,SLC1A4,SLC35B4,ABCD1,CAMK2G,RNF5,RBM15B,MLEC,RHOA,SNX2,RANGAP1,PNPLA8,RHOT2,NEU1,RAB18,CACNB1,SEC23IP,KPNA4,PDCD6,ATP6V1D,GOLGA7,BIRC5,SNAP29,E2F1,GLG1,PGRMC1,IMPDH1,USP20,FAM126A,PKD2,RBPJ,SPCS3,NR2F2,PGAM1,CHMP7,TXN,NUP188,PDCD6IP,ADAM10,TSC22D3,TMEM109,AP3M2,TAP1,GYG1,NHLRC3,CCNB1,SLC20A1,PARK7,RIC1,SLC25A37,KIFC1,PA2G4,SNUPN,ASAP2,CYB5RL,RAB4A,AP2B1,SLC26A2,MARCH2,TFG,SEH1L,SRSF10,SRP72,ORAI2,USO1,OSBP2,ATG9A,AKT2,ARHGAP45,NOL8,MRNIP,DDX20,SLC17A5,AURKB,MCFD2,SLC25A5,ZFAND5,RAB2B,CLNS1A,IWS1,HHEX,WAS,TMED10,PSMD8,RPS14,MAP4,EIF2D,ITGB1,SARAF,BTF3,RRS1,ARRB2,SLF1,RTN3,ZMAT3,NMD3,SVIP,HSPH1,COX5B,DNAJC5,MAPRE1,GMFG,ANKH,VAV2,ACAP1,KIF23,B4GALT1,NDUFA4,MAN2B1,SLC35B1,SUPT7L,PSEN1,TMEM165,VPS25,COPG2,NDUFS7,NPLOC4,JMY,SPAG5,RTKN,FKBP1A,TMEM250,SLC31A1,ARPC5,SNX18,LRRC8D,SLC25A51,ATP6V0A2,OSTF1,CYC1,PIKFYVE,LPCAT1,SYTL3,APOL1,TMED2,TERF2,MORC3,EIF5A,FTL,GCC2,SIGMAR1,WDR1,EMB,C1orf35,SEPT8,RPS24,ARID1A,ADRB2,CAPZA2,PKM,CYFIP2,FXR1,PTTG1IP,TOMM40,GOSR1,CCT8,PSMB3,XRCC5,PI4K2A,DERL1,SEC31A,CAT,EPRS,SLCO4A1,GOLGA2,NSF,CSNK1G1,ERGIC3,ACLY,ARAP1,APPL2,PPP3R1,FAM83D,GPI,YY1,PPP6R3,CDK2,NRBP1,NDC1,ATXN3,SYS1,CKLF,RAB11B,TRIP10,RAF1,GPR89A,RAC1,OLA1,SLC39A13,BCL2L1,SLC25A44,AP1B1,CD320,TERF2IP,MOAP1,APLP2,SHC1,TNPO2,CDKN1B,BRI3,TAP2,TP53BP2,TMBIM1,CFL1,CCT2,ATP13A1,CUL3,VDAC2,SLBP,LRRC8A,CDC23,PSMB9,AP4E1,ERC1,SERP1,SOCS7,HSPA4,CHMP4A,DSN1,JAK1,DDOST,RAB24,STAT1,SEL1L,EYA2,CSNK1D,DYNC1LI2,POU3F2,SCAMP3,SLC41A1,MECP2,MANBA,SLC25A12,SPDL1,RAB11A,HEATR5B,PIP5K1C,WWP2,SLC25A36,JAKMIP1,EBP,RPL17,PTEN,CENPJ,FUT8,PTPN11,AXIN2,RPL19,UPF2,SLC38A10,TAGLN2,CNN2,CREB1,MTX2,IFT46,PACS2,NCOA2,KAT2A,DENND1B,DENND4C,NET1,RPL8,RABIF,PACS1,KCNQ1,RHOT1,KIF11,RPL27A,MACF1,MARK2,SH3GLB1,SMAP2,YIF1A,HGS,RPL32,LTBP4,ATP5MC3,SLC38A7,CCZ1B,STX18,TFDP1,KHSRP,ASNA1,WDR91,ESPL1,GPR89B,IPO4,VPS29,ESYT2,ADA2,POLA2,IER2,NPHP4,MTX3,COPA,NF1,ALKBH5,UBE2Q1,PTP4A3,ABCB10,SLC29A1,KIF2C,AGFG1,SNRPD3,BECN1,MAPK14,ATP5PF,CUTC,PCYOX1L,DST,RAP1A,CDC42,GOT2,EIF4A3,AP3S2,RAB35,ATG3,ZNHIT6,DPYSL2,SRI,RPF2,KIF22,RP2,SLC35C2,CNNM3,CARMIL1,CARM1,TIMM50,FYTTD1,LARS,NCK1,TMEM216,SLC16A7,SLC25A22,PITPNB,MPC1,RPL37,PAF1,GEMIN5,HSPB11,EIF4ENIF1,UEVLD,TIMM29,MIA2,CAB39,STK11,CLU,VPS4A,ROCK1,RPS26,PSMC1,ATP6V0E1,CAPN1,STARD3NL,SLC12A7,TBC1D12,RPS15,TM9SF4,GORASP1,EPN1,TIA1,RPL15,MEF2A,XPO7,RHBDD1,PRPF18,NUP205,CHKA,BANF1,CAPZA1,ORAI1,KIFAP3,BCL2,GLTP,YBX1,ZRANB1,MCPH1,SLC12A2,ATP6V0D1,CSNK1G3,KDELR1,ATP5IF1,CREG1,ERLIN1,RPL6,PSMA1,SYVN1,SEPT7,TMEM241,CAND1,TSC1,CDCA5,ODF2,EXOC4,SLC16A1,NUP62,YWHAZ,CTSA,PITPNA,EHD4,TMEM14A,APOL2,WASF2,SNX27,CHMP2A,CORO7,TOMM20,ASH1L,CHERP,CLCC1,TWF2,HNRNPA2B1,ANKRD28,ANKLE1,SAR1A,KIF14,AKAP8,PPP6C,PARL,SCAMP4,CYB5R1,APOOL,CHTOP,CLTB,F2R,PDIA6,ABI1,SCYL3,CHP1,NXT1,SELPLG,PSMB7,WIPF1,ATXN1,TOR1AIP2,BICD2,OGDH,ERBIN,PEF1,TOLLIP,RPS9,SURF4,VPS26C,TULP3,ARNTL,CANT1,ANP32E,SCARB1,SMURF1,MAPK1,ABCA1,TSPAN5,TMEM33,MIF,KIF3B,GOLPH3L,RAE1,SCYL1,SRGN,DCTN2,VPS45,NUP54,CHIC2,TIMM21,MFSD10,XPR1,FERMT3,KIF5B,GRK2,KLHL20,SEC24C,RRBP1,NABP2,ZDHHC13,H2AFY,ARHGEF2,ANP32A,ATG13,YIF1B,LDLRAD3,FBL,STAT3,SLC35A1,MICAL3,MYO5A,SLC25A1,NIPAL3,TGFB1,ZDHHC18,CSNK1G2,PPP1R9B,ADAM17,FAM49B,NASP,ASPM,ATP2C1,SCFD2,COG1,WDR81,ATP5MF,SYMPK,MAPK3,MFN2,HSPA1B,LEMD2,UPF1,ELMO1,OSBPL8,COX8A,SRSF3,CENPT,ATP6V1C1,PLOD3,HRAS,SLF2,TERF1,RAB3IL1 |
| 2.155e-10 | -22.26 | HNRNPK (heterogeneous nuclear ribonucleoprotein K) | protein interactions | 3190 | 273 | 86 | 17029 | 2761 |
CYLD,IVNS1ABP,SF3B1,SUMO2,CUL1,UBE2I,SEC16A,PCBP1,LYN,RBM4,TERF2IP,VAV1,PA2G4,MDM2,EIF4A3,PIN1,CRY2,TARDBP,EIF5,CNNM3,CCAR1,PCBP2,CARM1,SRPK2,CDC5L,VHL,RAB7A,CIRBP,CUL3,HNRNPF,SREK1,BRCA1,DIDO1,MCM2,DHX15,SRSF1,DDX17,HSPA4,HNRNPR,SAFB,FUS,H3F3A,ARRB2,SMURF1,CBX4,DHX9,CDC73,SRRT,NPLOC4,LMNA,WWP2,RPA2,CTNNBL1,HUWE1,AHSA1,EFTUD2,YBX1,RBM3,PABPC1,HNRNPM,EEF1D,SPTAN1,SRSF11,YTHDC1,STAU1,RBM42,ILF3,ADRB2,PKM,MATR3,SF3A2,SNRPA,ISG15,RPA1,CAND1,HGS,SYNCRIP,CSK,RBMX,ACLY,DDX5,SRSF3,SNRNP70,CDK2,YWHAH,CD81 |
| 2.164e-10 | -22.25 | MORF_PRDX3 | MSigDB lists | MORF_PRDX3 | 77 | 35 | 17377 | 2626 |
TMEM106C,KARS,NDUFV2,NDUFS1,H2AFZ,HNRNPAB,DAP,ACTR3,STARD7,CYCS,AP3S1,PARK7,RAD23A,HNRNPA2B1,NDUFV1,AHSA1,RAD23B,HADHB,EI24,CYC1,IFRD1,PPT1,NSDHL,TUFM,MAP2K2,SRSF1,SDHB,HSPA4,PRDX3,PPM1G,COX5A,KPNA2,MDH1,AP2S1,HDAC2 |
| 2.206e-10 | -22.23 | WELCSH_BRCA1_TARGETS_DN | MSigDB lists | WELCSH_BRCA1_TARGETS_DN | 138 | 51 | 17377 | 2626 |
SRM,GALK1,NUP188,RAE1,MOGS,SMARCA4,SLC29A1,PRKACA,PABPC4,USP5,SF3B2,FARSA,FGFR3,PSMD1,ATIC,SEC24C,CDC25B,CYC1,PHKG2,FDFT1,CDC37,SRSF11,MLEC,KAT2A,PRRC2A,CDC123,NSDHL,EZR,MCL1,BMS1,VDAC1,MCM2,SOX4,EIF4H,CHAF1A,XRCC5,ALG3,SLC19A1,AGPAT2,BRD2,SCAP,SAFB,PIEZO1,TCOF1,SNRNP70,PDCD11,HRAS,GCSH,ANXA11,BYSL,SSRP1 |
| 2.213e-10 | -22.23 | nucleic acid-templated transcription | biological process | GO:0097659 | 2602 | 504 | 17256 | 2622 |
ZBTB10,TXN,ZNF496,MAX,KDM4A,CXXC1,CCNL2,CCNB1,COMMD6,EDRF1,POLR3K,MYEF2,ZNF275,PA2G4,USF1,CIPC,NOL11,FIZ1,SRSF4,ZNF200,CRY2,TAF5L,ECD,ZNRD1,DNMT1,ZNF800,CDC5L,ZNF524,ZNF672,ZNF559,KLF10,GABPA,ELOA,MIER2,TOPORS,USP22,DIDO1,CBFB,IWS1,BRMS1,HHEX,SMAD2,BRD2,ZNF689,VIPAS39,BTF3,TFDP2,SMAD1,ARRB2,E2F2,ZNF75A,CCDC59,HDAC2,SLC25A33,PTOV1,SSRP1,HIVEP3,EWSR1,POLR2K,PRKAA1,DHX9,EZH1,PMF1,NOTCH2,SUPT7L,ZNF79,ZNF518A,VPS25,CDC73,YY1AP1,CNOT3,MCTS1,TFAP4,LHX8,INTS7,KLF16,HDAC7,ZNF326,FOXN2,CPSF4,EEF1D,SRSF11,PHF10,ZNF84,ETV3,FOXK1,ELL2,RB1CC1,ZMYND11,ZNF574,MYBL2,BCLAF1,ARID1A,SRSF5,CBFA2T2,ELK1,KDM3A,PHF6,TWISTNB,XRCC5,ZNF777,SERTAD2,POLR2J,ETS2,ZFP92,SETD3,RBMX,MED15,PIAS2,CEBPG,CNOT6,YY1,RNF14,NRBP1,SGF29,ZNF511,ZNF296,SARNP,ATXN3,TRERF1,IVNS1ABP,ZBTB37,SUZ12,PTTG1,CREBL2,ZNF267,INO80E,SAFB2,RCOR3,TCF19,TERF2IP,SPINDOC,ZNF420,ZNF75D,SP100,KDM2A,ZKSCAN1,MTA1,UCHL5,GMEB1,LPIN2,NABP1,INTS12,ZNF226,ATF2,RPRD1B,CDK12,CGGBP1,SAP30,CPNE1,BRD4,POLR2L,EID1,ERF,KAT7,DRAP1,INTS13,WBP2,POLR2D,RNPS1,E2F3,SLBP,ELP4,EDF1,MEF2D,TRIM28,CENPU,PRDM11,SUPT16H,DDX17,TAF2,CHCHD3,VEZF1,ZNF282,HINT1,SAFB,HIPK2,STAT1,ATF6,SNRPG,BEND3,PPP5C,ZBTB11,EYA2,ATMIN,POU3F2,COMMD10,NCOR2,ZNF786,ZNF445,DEPDC1,SRSF6,MECP2,TWNK,TCF3,HABP4,JMJD6,ARGLU1,MYNN,WDR5,ETS1,HMG20A,FOXO3,MAD2L2,NEXMIF,ZNF92,WWP2,GTF2F1,CCNK,ZBTB45,SUV39H2,ELP5,PPP1R8,ZNF260,PRDM4,CARF,CITED2,CNOT6L,ZNF710,CREB1,GTF2H2,MED22,NCOA2,TSHZ1,PDPK1,ZFP64,KAT2A,ZNF512,RFXANK,ILF3,DDX39A,COMMD4,KLF6,POLR2A,CBX3,ZNF180,ZNF862,KEAP1,ZHX1,PITX1,TFDP1,LRPPRC,PML,KHSRP,DDX5,HMGB2,USF2,TAF6,PURA,THAP5,RORB,CCNC,ZNF76,IER2,THOC1,GPBP1L1,KMT2E,PHRF1,RBM8A,CSNK2A1,ZNF107,TAF6L,SND1,SIRT2,SNRPD3,COMMD5,MAPK14,SNAPC4,BIRC2,ZNF696,PAPOLA,CREM,LIN9,GLIS2,EIF4A3,ZNF639,INTS1,JAZF1,ETV6,PHTF1,NOC2L,ZBTB22,TCEA1,MYBL1,ARID4A,CARM1,CCAR1,RYBP,ELOF1,SP3,DEAF1,BAZ2A,SNRPB,RIOX2,MRPL12,PBRM1,BRCA1,EAF2,KMT2C,SOX4,USP21,ASF1B,PAF1,UBTF,BRWD1,CHD3,E2F4,ZNF367,PQBP1,CRCP,BAZ1B,ZNF268,CHEK2,DVL1,ZNF45,BEND6,FAM208A,ZNF564,FUBP1,ZCCHC9,PHB2,ZNF768,NACA,CTCF,CHCHD2,MED13L,MEF2A,CDK13,THRAP3,RLF,ASXL2,CNOT11,TTF1,SRRT,ARID1B,LYAR,SUB1,RB1,MLX,NFATC3,MED8,ZNF449,MED10,MBD2,SSBP3,ZNF746,BUD31,ZNF335,CTR9,TIMELESS,MDFIC,ICE2,YBX1,MAML1,ACAD8,PREB,ZNF189,VOPP1,POLR2I,CIC,LDB1,UTP15,RTF1,ZNF761,SLTM,DAPK3,IRF5,ZNF174,RXRB,NFIL3,TBPL1,PRMT7,NUP62,ZFP90,RUVBL2,RBBP4,HNRNPDL,ZBTB24,ADNP2,TCF12,MBD1,ASH1L,TRAF7,MPHOSPH8,ARID2,FOXM1,DYNLL1,XAB2,ZNF416,SMARCA4,RRAGC,PLAGL2,NSD3,IRF3,CHD1,ZNF121,COMMD8,MEAF6,MXD1,SAP130,RRN3,NRF1,ZBTB21,ZNF473,KMT5C,ZNF302,CD3EAP,AKAP8,RPAP1,TARDBP,CHTOP,UTP4,SAP30L,ZNF770,DVL2,ZNF583,RLIM,CSTF1,KDM3B,POU2AF1,POLR2G,ZNF780B,ZNF500,BTG2,PCGF6,ATXN1,NFATC2,KDM1B,MBD3,SRSF1,ZNF317,RBL1,ZNF700,MAFK,STAT6,ARNTL,ZNF436,DNAJC17,NCOA1,AKNA,BRD9,MAPK1,SMAD4,CBX4,INTS2,NAT14,SLC30A9,DNAJC2,CTDP1,NIFK,CDC40,MTERF1,ZNF316,EYA1,SCYL1,AGO2,ARID5A,KLF13,PAWR,GTF3A,NKRF,MXD4,PAGR1,IRF4,KMT5A,NABP2,BRD7,ANP32A,SS18L1,POLR1B,STAT3,RBM15B,SAMD4B,GTF3C6,RPRD1A,HMGN5,PSPC1,ZNF202,MIER1,ZMYM5,RCOR1,POLR3GL,PCGF1,MEN1,ZNF407,SYMPK,MAPK3,TFEB,CNOT9,ATAD2,BIRC5,L3MBTL3,TFE3,CDCA7L,BBX,E2F1,KMT2B,RBPJ,SRSF3,TAF12,NR2F2,ZMIZ1,HIPK3,IFI16 |
| 2.231e-10 | -22.22 | GO_ATPASE_ACTIVITY | MSigDB lists | GO_ATPASE_ACTIVITY | 401 | 109 | 17377 | 2626 |
DDX47,ABCA3,ABCC10,CHD1L,YTHDC2,TAP1,PMS2,OLA1,MYH9,DHX8,SMARCA4,ABCB10,KIF2C,ATP6V1B2,CHD1,KIFC1,ATP6V0B,ATP2A2,EIF4A3,KIF14,XRCC2,ATP13A3,KIF22,TAP2,TOP1MT,ABCC5,ATP6V1G1,SNRNP200,RHOBTB3,RFC3,ATP13A1,KIF15,ATP6V0A1,DDX20,RFC2,DHX15,DHX57,RAD54B,DDX17,KIF2A,RAD51C,ATP1A1,IDE,RAD18,KIF18B,CHD3,DHX16,MYO18A,ATP6V0C,XRCC3,CLU,VPS4A,PSMC1,ATP6V0E1,ABCA1,LONP2,RAD51D,DDX42,POLQ,KIF3B,RECQL,CHTF18,TOR3A,DHX9,KIF23,TOP2B,MYO9B,BLM,WRNIP1,KIF5B,STARD9,DDX56,KIF13B,MSH2,ANXA5,ATP6V0A2,DDX31,ABCD1,GTF2H2,ATP6V0D1,MSH6,ABCC1,DDX28,LONRF3,DDX24,DHX29,HELB,ABCF2,ATP2C1,DDX39A,KIF11,MACF1,ABCF1,CCT8,HSPA1B,PSMC4,XRCC5,DDX23,UPF1,ATP6V1D,KIF18A,ATAD2,NSF,DDX5,ASNA1,RUVBL2,RBBP4,ATP6V1C1,DDX52 |
| 2.239e-10 | -22.22 | COX15 (COX15, cytochrome c oxidase assembly homolog) | protein interactions | 1355 | 193 | 67 | 17029 | 2761 |
NDUFA5,IMMT,TXN,HNRNPAB,DYNLL1,HNRNPUL2,CLCC1,OAT,SAFB2,PABPC4,MRPL50,IARS,EIF4A3,RPN2,TECR,CHTOP,RPL35,RAB7A,VDAC2,RNPS1,VDAC1,SLC25A5,MRPS14,H2AFV,TRIM28,STOML2,SUPT16H,CHMP4A,ATP1A1,DDOST,TMED10,SAFB,CHMP4B,CLN3,NDUFS1,FLOT1,LAMTOR3,TOP2B,NDUFA4,ARF1,THRAP3,BLM,SCYL2,TFRC,NDUFS4,RPN1,ERH,GART,BANF1,RTCB,NDUFS8,CYC1,FBL,PABPC1,RHOA,ERLIN1,SF3B6,LDHA,ATP5MF,RPL36,NAP1L1,RPL32,PRDX3,HNRNPH3,RBBP4,HNRNPDL,ZC3HAV1 |
| 2.276e-10 | -22.20 | YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_10 | MSigDB lists | YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_10 | 60 | 30 | 17377 | 2626 |
USO1,SARNP,POLR2L,DYNLL1,CDK2AP2,NSUN2,VDAC2,LDHA,TM9SF3,RANGAP1,EDF1,FKBP2,EIF1B,EIF3G,SERP1,PRDX1,SAC3D1,PCNA,SLC1A4,SEC61A1,HNRNPR,TIMM23,DAD1,RRBP1,RPN2,MRPL40,OSTC,GCSH,TMED2,SSRP1 |
| 2.287e-10 | -22.20 | GSE32986_GMCSF_VS_GMCSF_AND_CURDLAN_LOWDOSE_STIM_DC_UP | MSigDB lists | GSE32986_GMCSF_VS_GMCSF_AND_CURDLAN_LOWDOSE_STIM_DC_UP | 184 | 62 | 17377 | 2626 |
WSB2,NQO1,TRIP10,RPS6KA1,FAM129A,DCTN2,TKT,BCL2L1,NANS,SLC35B2,PPP1R16B,PDXDC1,PARK7,TFRC,FZD6,MAN1A1,ANKRD28,RPN1,INTS7,DNAAF2,RAD23B,ARL6IP1,ANXA5,RNF19A,RNF135,PDIA6,F2R,ATP6V0D1,KCNAB2,BAK1,PPIF,TACC1,ELL2,NSDHL,CPOX,NARF,GBA,SEPT8,ATXN1,NUSAP1,ICMT,MCM2,PCGF1,KIF11,TARS,KIF18A,CDCA4,SEC61A1,PRDX3,TFE3,NEIL3,CORO1C,ACAT1,ADAM9,SSNA1,CTSA,REEP4,GLCCI1,CD81,NRBP1,PFKP,GEMIN7 |
| 2.287e-10 | -22.20 | GSE41867_DAY6_VS_DAY8_LCMV_ARMSTRONG_EFFECTOR_CD8_TCELL_DN | MSigDB lists | GSE41867_DAY6_VS_DAY8_LCMV_ARMSTRONG_EFFECTOR_CD8_TCELL_DN | 184 | 62 | 17377 | 2626 |
DNAJC2,NUP188,C19orf53,RWDD1,SCOC,MRPS26,NDUFA4,SLC35B1,SNRPD3,UBE2I,BZW2,PNO1,NDUFS7,COPB2,RAD23A,USP5,TMEM69,RPA2,CBWD2,CD3EAP,RBM34,TRMU,POP7,NSFL1C,NOC2L,TIMELESS,DCP1A,RPAP1,NDUFB9,AHCY,TTC4,CEP63,ALDH18A1,EIF5,TMEM14C,SEH1L,LYPLA2,HNRNPM,ALDH9A1,NUDC,JMJD4,TIMM8B,IFRD1,HARS,FAM118B,PPIE,UTP15,USP10,NUTF2,UTP3,MCM2,DDX39A,HAGH,CAND1,ORMDL2,AEN,ASNA1,SPRYD4,COPS6,MRPL13,SLC25A39,AAAS |
| 2.374e-10 | -22.16 | RPS9 (ribosomal protein S9) | protein interactions | 6203 | 165 | 60 | 17029 | 2761 |
RPS15,RPS2,CYLD,RPLP2,EIF3D,RPL15,CUL1,EBNA1BP2,SND1,EIF1B,APP,PABPC4,PNO1,RPL11,RPL23A,RPA2,LYAR,DDX56,EIF4A3,PTEN,RPL17,HUWE1,ZNF746,RPL19,TARDBP,STAT3,STAU1,EIF3L,RPL35,SEC61B,VHL,RPS10,RPL6,RNPS1,CUL3,RPL8,RPL38,RPS24,BCLAF1,BRCA1,MCM2,RPL27A,RPSA,EIF3A,EIF3H,CHAF1A,RPA1,RPL36,CAND1,RPL37,RPL32,RPS14,H2AFX,FUS,RRS1,FAU,CDK2,CD81,SMURF1,RPS26 |
| 2.454e-10 | -22.13 | GSE41867_NAIVE_VS_DAY8_LCMV_EFFECTOR_CD8_TCELL_UP | MSigDB lists | GSE41867_NAIVE_VS_DAY8_LCMV_EFFECTOR_CD8_TCELL_UP | 180 | 61 | 17377 | 2626 |
MIF,HIVEP3,CCNC,KARS,MRPL9,NDUFAF2,MAGED1,EIF3D,HNRNPUL2,PLAGL2,ARFIP2,ORC1,IKBIP,PSMD9,KTN1,LYAR,IRF4,ERH,SNUPN,SUV39H2,VMP1,RAB35,PIN1,SLC44A1,EFTUD2,BTF3L4,TECR,CNOT6L,SPTSSA,SGCB,UBE2M,SENP1,MRPL32,NOL12,TDP1,DCAF6,PIGT,POLR2G,RNASEH2C,SIGMAR1,GLO1,NDUFA7,TOMM40,GFER,AMZ2,CDC16,DSN1,NIP7,PSMD3,EIF2D,NFIL3,EXOC4,C4orf46,ATF6,GPI,WDR76,RUVBL2,CHPT1,HRAS,ZC3HAV1,DDB1 |
| 2.454e-10 | -22.13 | GSE19825_NAIVE_VS_DAY3_EFF_CD8_TCELL_DN | MSigDB lists | GSE19825_NAIVE_VS_DAY3_EFF_CD8_TCELL_DN | 180 | 61 | 17377 | 2626 |
BCL2L12,GLT8D1,PLXNC1,SCAMP3,ANXA6,CLSPN,RAF1,ZFP91,CDT1,CUTA,MRPS26,VTI1A,RACGAP1,TBC1D13,NANS,SAFB2,STMN1,NDUFS4,C12orf10,RPA2,SNRNP25,ERH,LRRC8D,PPP1R8,DDA1,SLC38A10,MDFIC,CENPM,PRADC1,MRPL21,SYTL3,S100A6,PDCL3,RPAP3,GTF3C6,ZNF672,HMGN5,NSDHL,RABIF,MRPL16,PLEC,SYVN1,MAPK3,C1orf122,ZNF282,ORMDL2,AGPAT2,KIF18B,DUS3L,SCAP,ZNF330,CHCHD1,CDCA5,NDUFA11,MRPL27,TBPL1,FTSJ1,AP1S1,COPS6,PSMC1,AAAS |
| 2.624e-10 | -22.06 | GSE45739_NRAS_KO_VS_WT_ACD3_ACD28_STIM_CD4_TCELL_UP | MSigDB lists | GSE45739_NRAS_KO_VS_WT_ACD3_ACD28_STIM_CD4_TCELL_UP | 176 | 60 | 17377 | 2626 |
BCCIP,GNPNAT1,RRP15,URB2,PPP1R15B,ADO,ACTR3,SLC2A1,BCL2L1,CCNB1,CRLF3,SRRT,POLR3K,PNO1,LYAR,SUV39H2,CD3EAP,GEMIN6,FOXN2,RPF2,BCL2,NUP153,SEH1L,NUDC,RYBP,SRSF10,GUK1,MAPKAPK3,IDH3A,TEX10,HNRNPF,GTPBP4,MFNG,RRM2,SLBP,RABIF,CDC6,GAR1,DDX39A,CBFB,KLF6,CCT8,EML4,DHX15,TMEM201,RAB18,KPNA4,TIMM13,ETS2,ZHX1,NIP7,ZNF330,TIMM17A,ZNF367,C1orf109,PITPNA,PRPF4,RRS1,NMD3,PRPF4B |
| 2.624e-10 | -22.06 | GSE17721_CTRL_VS_LPS_1H_BMDC_UP | MSigDB lists | GSE17721_CTRL_VS_LPS_1H_BMDC_UP | 176 | 60 | 17377 | 2626 |
KARS,PTMS,NAT9,MIF4GD,UBN1,EYA1,MAGED1,GSPT2,CDK2AP2,BABAM1,DCTN2,GADD45G,TPX2,STMN1,CRLF3,PIP5K1C,CAPN2,NAPG,ZBTB45,RAD23B,SRI,ALDH18A1,GCC1,PCBP2,SPSB3,CGGBP1,FDFT1,BAK1,PPP3CA,PSRC1,KLF10,OXR1,ATP2C1,MFNG,MYBL2,TBRG4,FBXO9,BMS1,CAPZA2,VKORC1,ANLN,SOX4,ARPC1A,FANCE,SLTM,GIGYF1,CLNS1A,ASF1B,NECAP2,OSBPL11,ITGB1,RPLP1,ZNF436,BAZ1B,CNOT6,ZFP90,RBBP4,AP2S1,PFKP,CSNK1D |
| 2.651e-10 | -22.05 | GO_CHROMOSOME_LOCALIZATION | MSigDB lists | GO_CHROMOSOME_LOCALIZATION | 57 | 29 | 17377 | 2626 |
CHMP2A,PSRC1,PDCD6IP,ACTR3,CENPF,CUL3,CDCA8,KIF2C,CDC23,CCNB1,CHMP2B,BECN1,RAB11A,KIFC1,CHMP4A,KIF18A,BIRC5,KIF14,CDCA5,CEP55,FAM83D,KIF22,CHMP4B,VPS4A,RRS1,NDE1,CHMP7,TERF1,SEH1L |
| 2.655e-10 | -22.05 | biliary_tract | COSMIC cancer mutations | biliary_tract | 15787 | 2430 | 17385 | 2587 |
HECA,ZBTB10,ABCC10,HEXB,CCNL2,FBXO22,EEF2K,RAD23B,ATP13A3,DNM2,ZNRD1,FTSJ3,USP34,ERCC1,NRAS,EHMT1,KIF15,HNRNPF,WDHD1,MIER2,DIDO1,MCM2,RAB22A,SMAD2,MID1IP1,RPS27A,OGT,MPV17,COX5A,SMAD1,ZNF75A,ANXA11,SLC25A33,SEC61G,GGA1,MUM1,TRIO,CUTA,RAB23,KCTD17,HAUS4,EIF2AK4,APH1B,CDC73,MYL6B,ATG4A,TMEM179B,PDXP,SMC3,GEMIN4,MVP,NUP85,PABPC1,NSUN4,PPA1,IFRD1,AGGF1,FOXK1,RBM42,GTPBP4,MAP7D1,MRPL16,ELK1,EIF4H,RDH11,MAGED2,KPNA1,ETS2,TYW5,WIPI2,RUFY3,PDLIM5,ACSF2,EXOC3,RHOG,STARD7,VTI1A,C5orf30,SLC35B2,INO80E,RCOR3,LCLAT1,CPNE3,KIAA1147,RBM23,ZNF420,AHCTF1,TBC1D22A,TBC1D14,GMEB1,NSFL1C,SEPT11,GPD1L,ZC3H3,ARL5A,PDCL3,SNX8,ERMP1,EID1,IDH3A,POLR2D,HTATIP2,MEF2D,TMEM147,GSTCD,TANC1,MAT2A,VPS26B,CORO1C,NSMCE2,CAMKMT,PPP5C,PITRM1,TUBB,COMMD10,ZNF445,SRSF6,HABP4,CCM2,FLOT1,BTN3A1,ATG2B,ABHD14B,PPP1R3B,ZBTB45,HUWE1,ZNF260,NAA50,ANXA5,LTN1,UBE3B,NAP1L4,ZNF710,ST8SIA2,SPTAN1,STAU1,DDX24,TACC1,MRS2,LDHA,HEBP2,LLPH,RAB3IP,TTC33,PICALM,SH3BP5,SLC19A1,ACOX1,FAM3C,AEN,PARP10,YWHAH,THAP5,GPATCH4,FAM129A,TRIM11,YTHDC2,SNX15,RBM8A,ENSA,NENF,SND1,RUFY1,TRIM65,ZER1,PRNP,KRR1,RAB8A,NUP210,NT5DC1,NOC2L,EIF5,TACC3,VPS13B,PTPN18,MIOS,SNRPB,MBLAC2,CDC6,UTP3,PBRM1,ODC1,USP21,TRAM2,FBXO28,BCL7C,ARRDC1,ADAM9,DVL1,NUMB,ZNF564,FUBP1,C1orf74,PARP12,ZCCHC9,CENPF,LAMTOR3,CHCHD2,NCKAP1,LYRM2,RSAD1,TNS3,SUB1,RINL,SSBP3,KIF13B,MBD2,XPA,AHCY,RBM3,LRSAM1,HDHD2,NTPCR,NSDHL,AMD1,CAMSAP1,ZNF761,METTL22,ICAM2,STYXL1,APPL1,BBS12,RXRB,SDHB,PCM1,GALNT2,TMEM168,NLRC5,RUVBL2,BTBD10,MYO9A,CCNB2,USP7,GLT8D1,RPLP2,SUCLG1,ARID2,TMX4,SLC2A1,ATP6V1B2,PCBP1,LYN,BCAP31,VAV1,TMEM69,MRPL50,PSMA6,ZNF473,BRPF3,TARDBP,BCAP29,CTDSP2,PRPF19,PPIF,KDM3B,MND1,CLCN3,BIRC3,RAB7A,ANKRD33B,PPIE,CHMP2B,VDAC1,EIF3H,TMEM201,GLOD4,IDE,DHX16,UHRF2,XRCC3,CHMP4B,PARD3,BCL2L12,C19orf53,MCM10,KLHL21,PDAP1,TMX3,CDCA8,ARF1,SLC12A9,TUBGCP2,DNAJB9,HOMER1,POLR1B,RNF5,RBM15B,PPAN,RHOA,RPRD1A,BTAF1,TOP3A,ARHGEF12,PCGF1,DDX23,RAB18,CACNB1,TRIM26,PDCD6,ATP6V1D,L3MBTL3,FAM110A,NEIL3,CTBS,BBX,IMPDH1,TAF12,NR2F2,PGAM1,HIPK3,IFI16,TXN,NUP188,H2AFZ,PRKCSH,USP39,UBE2I,PARK7,SLC25A37,ASPHD2,ZNF428,TRA2B,SUCLG2,CISD2,TAF5L,SMARCE1,ZNF800,CDC5L,ZNF524,SGCE,OSBP2,NSUN2,USP22,CLNS1A,EIF3A,ZMYM3,DOT1L,IWS1,ANKRD10,WAS,KIF18B,TPP2,C1orf109,ZMAT3,B4GALT2,PRPF38B,RECQL,C9orf78,EWSR1,GADD45G,RRM1,ACAP1,B4GALT1,CYCS,FAM136A,SUPT7L,TMEM165,CNOT3,WDR48,SPAG5,RTKN,CEP104,EXOSC7,KLHL5,LRRC8D,PPP4R1,MSH2,PIGG,FBXL7,OSTF1,MRPL40,TNRC18,SYTL3,FAM171A1,APOL1,EIF5A,GCC2,PRIM2,ELL2,RDH10,MFNG,RPS24,GORASP2,CAPZA2,ADRB2,CCT8,MTR,PHF6,PFDN5,SLCO4A1,TTC13,GOLGA2,RBMX,PIAS2,APPL2,SAMD8,NUDT3,CDKN2A,ZNF511,ATXN3,RAF1,KIAA0232,C2orf49,EPM2A,CD320,CCNA2,MTMR4,BRI3,TP53BP2,AQR,RBM12B,ILKAP,CDK12,SAP30,BRD4,DRAP1,NARF,LRRC8A,ELP4,ABHD11,PKMYT1,ASB13,SERP1,TRIM28,SUPT16H,EIF3K,CHMP4A,ATF6,XRCC4,PRPF4B,ADAM23,NDUFS1,DEPDC1,MECP2,SECISBP2,HMG20A,WWP2,SLC25A36,JAKMIP1,DNAJC8,AXIN2,CITED2,JMJD4,ANKRD37,KAT2A,TMEM126B,RABIF,ADSL,PACS1,BMS1,KCNQ1,ARSK,MACF1,KIF11,KLF6,COMMD4,SMAP2,FADD,SH3GLB1,MYO1F,CBX3,TMEM127,INF2,PPP1R11,DUSP11,DDX5,WDR62,TAF6,ESPL1,PURA,DDB1,DEF6,FAM83G,IPO4,UBL3,PIGM,NAT9,LYRM4,GPR132,UBE2Q1,PTP4A3,BRIX1,MRPL19,ZNF696,SF3B2,PCYOX1L,CDC42,GOT2,JAZF1,HADHB,RPF2,SLC35C2,CNNM3,CARM1,SRPK2,WDR41,LARS,ZCCHC10,CCDC138,LRBA,SUMF2,KMT2C,OGFR,PRPSAP1,ASF1B,RPL37,MAN2A2,EIF4ENIF1,NIP7,U2SURP,MIA2,ATP6V0E1,PPP1R2,PM20D2,XPNPEP3,RGS2,LYAR,FAM89B,POLR2I,TRAFD1,SUGP2,GBA,SYVN1,DAPK3,ARHGAP15,MASTL,UAP1,NFIL3,FN3KRP,YWHAZ,CTSA,TMEM14A,TOB1,TSEN15,ADNP2,TCF12,PRKAB1,MDH2,SMARCA4,ORC1,RRN3,UBXN2A,IARS,CD3EAP,KIF14,EXOSC1,CS,CLTB,DNAL4,CSTF1,POU2AF1,UBQLN4,NXT1,HPDL,PGGT1B,SELPLG,SMU1,ATXN1,GLO1,OGDH,BICD2,CADM1,EDEM2,HERPUD2,TOLLIP,FANCE,MBD3,PDHX,RPS9,ALKBH6,SURF4,DUS3L,ARNTL,ANP32E,FKBP5,TMEM101,CCDC125,ABCA1,PDCD2L,GCLM,RAE1,NUP54,CHIC2,PAWR,MXD4,DCUN1D4,PIP4K2A,XPR1,FERMT3,KIF5B,KLHL20,SEC24C,RRBP1,ARHGEF2,LDLRAD3,STAT3,MYO5A,NIPAL3,AMPD2,TXNL1,PHF20L1,DCAF6,FAM49B,TMEM39A,ATP2C1,RFFL,COG1,RCOR1,PRMT2,TFEB,LEMD2,UPF1,ELMO1,ZC3H7B,DTX4,ZMIZ1,TERF1,HRAS,CCDC93,FGFR1OP,TMED7,PIGQ,AGPAT1,CNTROB,PPP1R16B,MIS12,GSDMB,TTC9C,PDS5B,NUP153,SENP1,PGAP2,TMEM115,DCUN1D5,PLEKHF2,BRMS1,PWWP2B,TRIM47,WDR11,AXIN1,SMG9,TRIM52,LONP2,NDUFV2,PHF23,CERK,SLC4A2,EZH1,ITGB5,LMNA,MCTS1,DDX56,EIF2S2,SLC38A5,FOXN2,CARS2,PRRC2A,C16orf72,RB1CC1,ZMYND11,PGS1,MYBL2,UHRF1BP1,SRSF5,MPG,MATR3,CYB5A,NCDN,POLR2J,SETD3,PTAR1,CNOT6,NDE1,EGLN1,ZNF207,ANKRD27,ABCA3,IVNS1ABP,RMI2,MON1B,TMEM97,NIT2,NUF2,ZNF267,TCF19,TMEM161B,KTN1,APP,PRKD3,CLUAP1,ATP2A2,UTP18,DUT,ZCCHC2,ANAPC7,RNF19A,FAM76B,CLN6,TMEM9,GCC1,RNF169,ADCY7,ATP6V1G1,ENPP4,RNPS1,CDCA2,FKBP3,GPR137,DDX17,CHCHD3,PEX5,CDC16,HIPK2,MBOAT1,TICAM1,ZBTB11,ANXA6,TMBIM4,GMCL1,UBE4A,IL21R,ETS1,WRB,ZNF92,PNO1,CAPN2,ADD3,SUV39H2,TTLL12,TPCN1,TMX1,LYPLA2,HNRNPM,LDHB,PPP3CA,NUDT8,POLK,JTB,EMP3,MTMR12,ZP3,PDE3B,KIF18A,CCDC6,WNT5B,MAPK6,C4orf46,LY75,SLC25A19,RGL1,PSAP,WDR76,IGBP1,FAF1,SNAPIN,COX15,THOC1,AGRN,GNPDA1,GPBP1L1,PPP1R15B,CSNK2A1,EBNA1BP2,GIT2,BIRC2,ATPAF1,DLG5,ABL2,XRCC2,ZFYVE27,MCMBP,PTPRK,CDC37,SP3,METTL1,EXOSC6,HARS,GMFB,ESYT1,ANLN,RAB5B,RHEB,DPYSL3,TBC1D17,TIMM13,CDCA4,TONSL,NRM,NAGLU,ACTB,ZNF45,TMUB1,CTCF,ASAH1,DOCK11,CRLF3,LRRC14,NUS1,SLC27A4,AFF1,MDFIC,MAML1,CYTH1,NQO2,UTP15,EIF2AK1,EIF4G2,ZDHHC3,MOSPD3,ITPRIPL1,CDC27,SNAP23,TBPL1,PRMT7,KCTD7,NDUFA5,CYLD,UGP2,DYNLL1,COPE,HCFC1R1,ZADH2,GGPS1,RAD23A,PDK2,ATP6V0B,STRBP,DUS4L,MRPL34,PDCD2,SAP30L,SLC39A9,CLPTM1,RPL29,RPL35,BTG2,DNAJC9,MTMR6,FRAT2,NFATC2,KDM1B,ARL5B,USP36,CCDC127,MRPL2,ATP1A1,CLK3,PSMD3,MAFK,CEP55,NDUFA11,DNAJC17,ZNF436,NCOA1,SLC25A39,ZC3HC1,ZNF146,ATXN7L2,CDC40,GOLIM4,SMAP1,RRP15,DAP,GNE,SMC6,ARFIP2,NKRF,CHAC2,BZW2,WRNIP1,SS18L1,CENPM,PTGES3,CAMK2G,MLEC,ZNF202,PPWD1,FAM50B,RHOT2,NEU1,TPD52L2,GOLGA7,TWSG1,GLG1,PGRMC1,FAM126A,RPS6KC1,UBE2C,PPCS,NDUFB6,TMEM41B,ZDHHC8,PLXNA1,CCNB1,SLC20A1,COMMD6,ABHD14A,POLR3K,C14orf119,ASAP2,SNUPN,TFG,PLCL2,SEH1L,ATG9A,PBK,MKI67,DDX20,AMDHD2,SLC17A5,GALNT7,CCNF,FOXRED1,PTER,WDR4,DHTKD1,TRAF5,HDAC2,PWWP2A,HSPH1,MAPRE1,CHTF18,ADO,KIF23,SLC35B1,NOTCH2,JMY,FKBP1A,SLC31A1,SNX18,ATIC,ATP6V0A2,PIKFYVE,RNF135,LPCAT1,EEF1D,TMED2,PHF10,FTL,DDX28,ZNF84,SIGMAR1,PIP4K2C,RIT1,PLEC,KDM3A,SF3A2,FAS,EPRS,ZNF777,TMEM54,QARS,PPP3R1,TCOF1,CABLES1,NRBP1,DNMT3A,RWDD1,CKLF,TRIP10,SF3B1,CAST,SUZ12,RPS6KA1,RAC1,GPR89A,OLA1,SNN,GNB2,FLAD1,APLP2,KDM2A,TNPO2,CDKN1B,TALDO1,GPX4,ATP13A1,RFC3,MAPRE2,ERF,CUL3,SLBP,H2AFV,GAR1,PSMB9,POLG2,DHX57,NSA2,HSPA4,MRPL55,JAK1,TBL3,SEL1L,H2AFX,KLHDC4,B4GALT3,PDCD11,ATMIN,POLQ,POU3F2,OTUD5,NCOR2,ANKRD13D,PKP4,SCAMP3,CDCA3,SLC25A12,BLM,TMCC3,GTF2F1,RPL17,CRAT,AHSA1,PRC1,UPF2,COPS7B,SLC38A10,CNPY3,UBE2M,IFT46,TMEM160,TSHZ1,ZFP64,DENND4C,WDR18,RPL8,ILF3,LRRC1,RHOT1,TSR2,MARK2,ECH1,PRDX1,PLD3,NUCB1,GNA12,FBXO21,C1orf131,PRDX3,PFDN4,HNRNPH3,STX18,TFDP1,KHSRP,ASNA1,CPEB2,SSSCA1,VPS29,BYSL,S100PBP,MIB2,IER2,PTMS,NOP2,UBN1,NF1,DCAF15,ALKBH5,MOGS,TAF6L,MAPK14,BECN1,SNAPC4,RNF103,BCAT2,MBD4,C18orf32,METTL14,ZNHIT6,IMPAD1,RCSD1,PHTF1,SRI,KIF22,ZBTB22,NFU1,OGG1,TRIM14,ELOF1,COPS8,FYTTD1,TRIM8,RRM2,SOX4,ABHD5,CXXC4,UBTF,PAF1,UEVLD,SPATA2,PQBP1,IARS2,ATXN2L,GALNT10,STARD3NL,RPS15,PIGN,AGTRAP,CIB1,XPO7,SRRT,ZNF449,CAPZA1,GLTP,KIFAP3,BCL2,N4BP2,HP1BP3,THNSL1,ISG15,CAND1,GNAS,TSC1,RBM25,CDCA5,ZFP90,NANP,RBBP4,ZBTB24,SMARCD1,MBD1,WASF2,MMACHC,TOMM20,IFI27L1,GNPNAT1,MPHOSPH8,HNRNPUL2,CHD1,MEAF6,C2orf68,CCDC50,AKAP8,PARL,RPN2,CHTOP,FAM3A,F2R,SCYL3,TMEM14C,ABI1,HTRA2,MOSPD1,RLIM,FAM172A,ZNF500,PSMB7,NLN,WIPF1,BOLA1,BUD13,NDUFB1,PEF1,EIF3G,BTBD1,TAB2,CHCHD1,TULP3,WDR59,CANT1,SCARB1,GAS2,USP11,SMURF1,PPP2R2D,TSPAN5,CDS2,MAGEH1,MRPL42,EYA1,CDK2AP2,MRPS26,LETMD1,KLF13,HDDC2,RGS1,MAN1A1,FBXO5,GART,TANK,BRD7,MRPL11,SAMD4B,ZDHHC18,GTF3C6,POLR3GL,WDR81,MEN1,ZNF407,MFN2,COX8A,ZRANB2,SRSF3,MBD6,ATP6V1C1,IDH3B,TATDN1,TSC2,LACTB2,CMTM6,RBM4,ZNF275,ANKRD39,RPL23A,CDKN2C,USF1,MECR,AP1M1,UPRT,CRY2,ECD,RNF26,TIPARP,LRRC59,ANKRD9,RHBDD2,MGAT5,BAK1,ZNF559,RHOBTB3,GABPA,WBP1,NUTF2,ARF4,GINS4,KRIT1,BOLA3,AHNAK,RAD18,PDRG1,RNASEL,CHPF2,OAZ1,SMNDC1,PDCD4,NXT2,HIVEP3,KIAA0100,CLSPN,RHOC,DHX9,PDCD7,PSMD9,HAUS2,COPB2,CD59,TFAP4,RNFT1,RIMS3,EFTUD2,FBXO7,CPSF4,MRPL21,PHKG2,LUC7L2,SRSF11,EIF3L,MTA2,TYW1,USP10,ITM2A,SSR2,BCLAF1,MTX1,SFXN5,FNTA,PDLIM1,TMEM159,MRPL3,ALS2,FAM72A,TRIM41,KARS,NQO1,POC1A,ANK3,PTTG1,TPX2,TBC1D13,DAZAP2,STMN1,C19orf48,REPS1,ABHD16A,FBXL6,SH3BP1,MTA1,UBA5,CLCN6,INTS12,C8orf59,RPRD1B,CGGBP1,CPNE1,SEC61B,POLR2L,FAM118B,GOPC,E2F3,CIRBP,RPL38,CRNKL1,PFKFB3,GORAB,RAB1A,GIGYF1,TMEM184C,PPP2CA,KIF2A,CCDC14,LSM6,RNF38,SNRPG,DMWD,USP13,ZFP91,TRMT6,IP6K2,WDR5,SLC25A43,IFT27,PMVK,NEIL2,RRP36,SRXN1,RPA2,PSMD2,CLIC4,PDCD10,CBWD2,COQ4,ITGB8,ARF5,ARHGEF1,FBXL19,TTPAL,UTP20,GPS2,DBI,SSNA1,MRFAP1L1,CD81,TMEM131,WDR13,FANCI,PAPOLA,CREM,FANCL,GLIS2,IL6ST,INTS1,POP7,SLC44A1,MTPN,ASB6,PLK1,RPP25,SEPT9,CELSR2,RBX1,APH1A,RAD51AP1,CKAP2L,PSMG1,UBE2V1,EAF2,IL12RB1,KRTCAP2,LUC7L,LSG1,NECAP2,C1orf122,ALG3,TRIM4,AGPAT2,CHD3,ZNF367,E2F4,PRPF4,KPNA2,BEND6,CLN3,DNAJC30,NGLY1,POT1,MYL12B,CCDC137,RMND5A,HJURP,PHB2,DNAJB2,FAM53C,NKD2,SDC2,KLC1,CDK13,ADCK5,COX4I1,DNAJB1,RAB6A,ARID1B,C1GALT1,MLX,UBE2Q2,CCP110,ZNF746,ARL6IP1,CTR9,NIPSNAP1,ABHD2,DCAF8,ACSL3,LDB1,MAP4K3,ARMC8,NMT2,IRF5,RPL36,HAUS8,MBIP,ORMDL2,COX7A2L,ZDHHC7,SIL1,FAM122A,UNC13C,BCCIP,SART1,TRAF7,NDUFAF2,TOR1AIP1,ZNF416,LAGE3,ZFYVE21,TM9SF3,RRAGC,ZNF121,OIP5,NRF1,WDR44,PIN1,EFCAB11,RPAP1,CABLES2,LMAN1,AHCYL1,TOP1MT,STRAP,SPSB3,ZNF583,SNX25,ARHGAP17,POLR2G,ZNF780B,PPT1,NUP155,DCLRE1C,MRPS14,RHBDF2,SUGP1,RBL1,FASTK,STK38,AP1S1,SPRYD4,H3F3A,CHID1,SMAD4,RAD51D,SLC30A9,UNK,CMAS,NADSYN1,HMGN3,NCAPG,SCYL2,FZD6,HERC3,GTPBP3,CTSS,ORC3,RNLS,YTHDC1,ACP2,HMGN5,CSRP1,METTL5,ABCF2,TUFM,RANGAP1,PNPLA8,HAGH,API5,ZFR,SEC23IP,E2F1,TMEM219,USP20,RBPJ,PDCD6IP,MAX,LUZP1,ADAM10,CXXC1,TSC22D3,AP3M2,CUL1,GYG1,NANS,OAT,MYEF2,ANKRD26,PA2G4,NOL11,FIZ1,ZNF200,MARCH2,SLC26A2,SRP72,KLF10,LACTB,RFC2,CBFB,RAB2B,MAP3K4,HHEX,LUC7L3,RPS14,MAP4,MRPL27,BTF3,PTPDC1,NMD3,CCDC59,PTOV1,COX5B,DNAJC5,SCOC,DHPS,POLR2K,ANKH,VAV2,C16orf87,PRKAA1,GSPT2,DLGAP4,PXMP2,PRPF39,PSEN1,ZNF79,PDXDC1,VPS25,NDUFS7,YY1AP1,C12orf10,FAM192A,RPN1,LHX8,ARPC5,ZNRF2,TPST1,DAPK1,PIK3IP1,CYC1,SOCS5,FDFT1,PIGT,EMB,WDR1,ZNF574,C1orf35,EXOSC9,ARID1A,PTTG1IP,C9orf40,FXR1,GOSR1,MAP2K2,TWISTNB,AKAP1,XRCC5,HMGN2,PI4K2A,CAT,SEC31A,DERL1,MTHFD2,HSPBP1,CEBPG,ARAP1,USP32,FAM83D,CABIN1,SMPD4,GPI,CYTIP,TP53RK,REPS2,RAB11B,UROD,SLC39A13,POMP,BCL2L1,DECR1,RALB,SIAH1,ADCY9,LPIN2,MRPS27,SOCS6,TTC3,RNASEH2A,CFL1,ANKLE2,CDC123,OAF,VDAC2,EDF1,EML4,ERC1,ANKZF1,RAD51C,ZNF282,DSN1,DDOST,HINT1,DGCR8,SAFB,HAGHL,FTSJ1,RWDD4,LMBR1,NCLN,BEND3,EYA2,DYNC1LI2,MANBA,SLC41A1,B4GALT5,FAM76A,TKT,CBLL1,ARGLU1,LANCL1,POFUT1,FAM8A1,HEATR5B,HLA-A,EBP,RFWD3,NDUFA2,FJX1,FUT8,BTF3L4,PTPN11,MRPL54,FEM1B,RPL19,CNN2,NDUFA3,MTX2,MSH6,PDLIM2,LONRF3,RFXANK,FBXO9,GUF1,RPL32,ZHX1,NDUFS5,WDR91,HIGD2A,ZBED3,RORB,POLA2,ZNF76,COPA,PHRF1,ABCB10,COMMD5,MAP1LC3B,DST,RAB35,SIVA1,GPATCH1,TCEA1,DRAM2,DEAF1,SNRNP200,LAP3,NCK1,VHL,SREK1,ARHGDIB,PITPNB,HSPB11,BRWD1,PPM1G,SH3GLB2,CRCP,BAZ1B,CAB39,ACBD4,STK11,CLU,CHEK2,ZSWIM3,TSTD2,CHPT1,MRPL13,DCAF5,CAPN1,UBE2D3,NSMCE4A,PPP1R12A,ZCCHC8,GORASP1,UBXN1,NACA,RPL15,PCSK7,THRAP3,QSOX2,TTF1,PRPF18,NUP205,CHKA,MED10,ZRANB1,MCPH1,SLC12A2,ATP6V0D1,CSNK1G3,CREG1,NUDT4,RPL6,VKORC1,SLTM,EVC2,KLHL15,SIAH2,SLC16A1,EHD4,SNRNP70,C11orf1,APOL2,N4BP2L2,SNX27,CHMP2A,CORO7,UCK2,PMS2,UCK1,CLCC1,EXT2,MXD1,USP5,HNRNPA2B1,SAP130,NVL,PPP6C,CYB5R1,ZNF770,EBAG9,RNF25,PCGF6,METTL2A,FAM72B,PON2,HPS5,STAT6,MAPK1,BRD9,TMEM33,NAT14,TRIP12,SHPRH,SCYL1,VPS45,MYO9B,GFM2,SPPL2A,FASTKD3,FGFR3,MZT2A,PPIG,ZDHHC13,TMEM99,H2AFY,NDUFS8,ATG13,ERI3,FBL,FRMD8,SLC35A1,MICAL3,TGFB1,B3GALT6,ELOVL5,HEMK1,TIMMDC1,HELB,PSPC1,MIER1,SCFD2,NDRG3,CDK11A,MTMR3,ACAT1,CENPT,PLOD3,RAB3IL1,RAB14,ADD1,MRPS15,KDM4A,XIAP,DHX8,GLUD1,ANKRD23,PABPC4,CALM2,CDK5,PSMD1,NEK6,NSRP1,RABGAP1L,SRSF4,FNIP2,KCNAB2,PCBP2,MLST8,PLK3,ZNF672,HSDL1,MRPL43,TOPORS,MCL1,SMC2,PPFIA3,ICMT,SLC50A1,STOML2,LIMK1,ZNF689,PRDX5,ATE1,MLYCD,ATP6V0C,ST3GAL2,FBXL3,TFDP2,E2F2,PFKP,AAAS,DDX42,SSRP1,MRPL9,MRPS2,STRN4,TOP2B,ZNRF3,TMED3,DDRGK1,RAVER2,GNS,INTS7,INPP5A,MCM5,PHF14,ZNF326,NAGPA,TIMM8B,ETV3,DHX29,TEX10,MAN1B1,RPS10,CBFA2T2,ABCF1,RHOB,LRRC14B,DTWD1,PTPRF,SCARB2,OSBPL11,CCDC86,DUSP3,SLAIN1,MDH1,HEXA,RNF139,SNX14,ZNF296,TRERF1,UBR2,CHD1L,ACTR3,WDTC1,MYH9,CREBL2,NIPA2,PRKACA,SAFB2,ANKIB1,STAM,ARL6IP6,RAB21,SP100,ZKSCAN1,DDA1,NUP107,ANKRD13C,MAVS,CEP63,TMEM136,RBM15,ATF2,DCTN1,SHOC2,PSRC1,MAP4K4,WBP2,ATP6V0A1,DNAJA1,NDUFA7,TAZ,TAF2,SEC61A1,WDR7,RPLP1,CBLN2,RBMS1,FUS,GEN1,LRP8,COIL,LRCH1,GALK1,ZNF786,RPS2,SESTD1,TRAK1,JMJD6,SIKE1,AKT1S1,KRI1,FBXO3,ERH,PPP1R8,PRDM4,GTSE1,GEMIN6,DCP1A,SGCB,S100A6,IMPA2,NUDC,PDPK1,TK1,GUK1,TNFAIP3,GALC,ZNF512,KIAA0930,MRPS10,DDX39A,RPA1,ZNF862,ZNF180,KEAP1,POLE,TATDN2,PITX1,CAPN7,LRPPRC,PML,HMGB2,USF2,ANAPC4,SRM,DDX47,MCCC1,CDC42SE2,S1PR2,CDIPT,SSR1,LIN9,PCNA,ZNF639,TRMU,PIK3R2,ETV6,PPCDC,TXLNA,FAM86C1,MYBL1,MRPL32,CCAR1,ABCC5,PBXIP1,BAZ2A,TLK1,MRPL12,EZR,LNX2,LRP5,BRCA1,PRKRA,STX16,EPB41,OPTN,SEPT1,SOCS4,QRSL1,PIEZO1,GLCCI1,NUDT11,GEMIN7,SEPHS2,LZTR1,RACGAP1,PPP3CB,B4GALT4,RLF,RAPGEF6,SNRNP25,RB1,VASP,MED8,VMP1,PPIL2,MEA1,TIMELESS,AHDC1,ALDH18A1,TMEM8A,ABCC1,PREB,TRAPPC9,AACS,MEMO1,KRAS,RTF1,UBE4B,NFATC2IP,LY6E,ARPC1A,ZNF174,PSMC4,GOLGA4,PALB2,SYNCRIP,PRPS2,NIPA1,TIGD2,RNF114,FOXM1,MRPL39,XAB2,SUMO2,DUSP22,COMMD8,RPL11,CSDE1,MDM2,CORO1A,METTL9,MINPP1,DVL2,GM2A,PSMA8,COQ10B,CPOX,TIGD5,SLC26A6,CYP20A1,PRPF3,TXNL4A,RPSA,SRSF1,DNAJC10,SCAP,ZNF700,PLEKHG4B,TIMM17A,FAU,LTA4H,AP2S1,USP53,INTS2,CTDP1,MIF4GD,CDT1,ARID5A,SUMF1,GGA2,AP3S1,CSNK1A1,RMI1,TFRC,PTPN2,STARD9,IRF4,GSTK1,NDUFV1,SLC1A4,CWC27,SLC35B4,DDX31,ABCD1,RPAP3,CNTN5,SNX2,ZMYM5,CCDC34,CHCHD6,BSDC1,KPNA4,CDKN2AIPNL,FBXO41,BIRC5,TFE3,SNAP29,CDCA7L,PKD2,ACADM,CHMP7,SAT2,GCSH,ZNF496,TMEM109,TAP1,NHLRC3,IKBIP,EIF1B,ELMOD2,KIFC1,DBNDD1,RNASEK,CDC25B,PRADC1,DNMT1,NOL12,ORAI2,AKT2,GNG7,AURKB,MCFD2,SLC25A5,ZFAND5,MAK16,STT3A,TMED10,PSMD8,EIF2D,ITGB1,PTPN7,UQCRH,RRS1,ARRB2,RTN3,SVIP,DDX58,WSB2,PPIB,MUT,GMFG,HLA-E,NDUFA4,MAN2B1,METTL3,CFLAR,NDUFS4,RNF121,MEX3C,KLF16,HDAC7,DAD1,BDH1,PCYT2,GNAI2,TERF2,MORC3,KCTD20,SEPT8,DCTD,TOMM40,ADSS,SERTAD2,SERF2,ZFP92,NSF,DCK,ERGIC3,ACLY,LPCAT4,VCPIP1,YY1,MAP3K5,PPP6R3,PPP6R2,RNF14,CDK2,ZC3HAV1,ZBTB37,URB2,EIF3D,MAGED1,KLHL18,ADPGK,SLC25A44,AP1B1,SDHA,PAIP2,PHC2,CRKL,MOAP1,TERF2IP,CYHR1,ZNF75D,SHC1,UCHL5,NAA35,TMBIM1,CCT2,CDKN2AIP,MKLN1,HMGN4,GALK2,CDC23,SHCBP1,AP4E1,PRDM11,VEZF1,PPP2R5A,ACYP1,STAT1,PPA2,TRIM32,RHEBL1,C1orf112,TCF3,MRI1,BRAP,AGPAT3,MYNN,SDF2L1,SPR,RAB11A,REEP5,FOXO3,MAD2L2,CCDC28A,PIP5K1C,RBM17,MAT2B,PTEN,CENPJ,TAGLN2,OSTC,CREB1,PACS2,NCOA2,SMC4,RNASEH2C,NEK7,NET1,PARP4,TBRG4,ANAPC2,RPL27A,YIF1A,SGSH,HGS,TTLL4,SLC38A7,MFAP1,CCDC69,BRWD3,ESYT2,SKA3,NPHP4,UBE2E2,PLXNC1,ST13,TMEM184B,DNAJC24,ZNF107,KIF2C,SLC29A1,AGFG1,SIRT2,FKBP2,USP48,UBQLN2,SNRPD3,CUTC,EDC3,UBLCP1,ZNF804A,RAP1A,THADA,EIF4A3,AP3S2,ATG3,DPYSL2,PPP1R12C,AKR1B1,NDUFB9,JOSD1,RP2,TTC4,TECR,ARID4A,FGFR1OP2,TIMM50,TDP1,DPM1,FOPNL,SLC16A7,WDR82,SLC25A22,STK17B,DHX15,CHAF1A,GEMIN5,COPS6,SASS6,RPS26,PSMC1,SLC12A7,TBC1D12,TM9SF4,ZNF768,UFC1,MED13L,TIA1,EPHX2,PITHD1,RHBDD1,NFATC3,BANF1,BUD31,ZNF335,YBX1,KNTC1,ACAD8,UBE3C,ZNF189,ALDH9A1,KDELR1,TSTA3,CIC,OXR1,PSMA1,NAP1L1,ODF2,EXOC4,KIAA1328,PITPNA,NAA20,PTDSS1,MZT2B,PDSS2,C7orf26,TMEM106C,IMMT,ASH1L,CHERP,WDYHV1,PLAGL2,CHKB,IRF3,TWF2,PAIP1,ANKRD28,FARSA,SAR1A,SCAMP4,APOOL,PDIA6,ACSL5,TOR1AIP2,AZI2,GFER,RAD54B,DAP3,TMEM41A,ZNF317,GADD45B,AKNA,REEP4,CBX4,MIF,KIF3B,GOLPH3L,SH2D3A,CASP6,TOR3A,SRGN,DBF4,MFSD10,SAC3D1,CTNNBL1,YIF1B,CLDND1,TTC17,SLC25A1,PAQR6,CSNK1G2,TELO2,ADAM17,HMGN1,NASP,ASPM,PPP1R21,PRKAR1B,SYMPK,TARS,SNRPA,MAPK3,HSPA1B,HLA-B,ATAD2,PLAA,ZNF330,OSBPL8,KBTBD7,PREPL |
| 2.724e-10 | -22.02 | GSE27786_CD4_TCELL_VS_NEUTROPHIL_UP | MSigDB lists | GSE27786_CD4_TCELL_VS_NEUTROPHIL_UP | 189 | 63 | 17377 | 2626 |
PWWP2A,GALK1,ZNF496,LZTR1,TRIP12,GNPNAT1,TRMT6,TAP1,AP3M2,OLA1,JMJD6,NKRF,THRAP3,EIF2AK4,IL21R,FAM8A1,MYEF2,ARID1B,RPAIN,NDUFS7,RRP36,RGS1,PTPN2,UBXN2A,NFATC3,H2AFY,AQR,APOOL,ORC3,TTLL12,NUP85,CCAR1,RLIM,CDC5L,USP34,FYTTD1,ANKRD37,NEK7,LDB1,MRS2,IL12RB1,RAB3IP,NDRG3,ODC1,KDM3A,PHF6,EIF3K,MAGED2,GNAS,EPRS,BRWD1,DUS3L,TTC13,PDLIM1,LUC7L3,PDXK,RRS1,FAU,GCSH,PFKP,IPO4,ALS2,RNF114 |
| 2.726e-10 | -22.02 | ORC1 (origin recognition complex subunit 1) | protein interactions | 4998 | 48 | 27 | 17029 | 2761 |
SRP72,RFC3,SCAMP3,MRPS15,ZNF768,KAT7,CDT1,DBF4,CIRBP,CDC6,CDIPT,MCM2,ZNF174,PHF6,XRCC5,DOT1L,RPA2,TRIM26,CCNA2,GOLGA2,MCM5,MRPL11,ORC3,CDK2,MRM3,TERF2,CDC5L |
| 2.756e-10 | -22.01 | TP53BP1 (tumor protein p53 binding protein 1) | protein interactions | 7158 | 142 | 54 | 17029 | 2761 |
ZBTB10,DYNLL1,SUMO2,SMC6,BLM,CCNB1,UBE2I,LMNA,RPA2,SUB1,KMT5A,PELO,NUP107,CAPZA1,ANAPC7,MCPH1,STRAP,NUDC,PLK1,FOXK1,MTA2,RCOR1,ANAPC2,NFATC2,BRCA1,DCLRE1C,CDC23,PCGF1,RFC2,TRIM28,MAPK3,SRSF1,RPA1,XRCC5,CBX3,SDHB,CDC16,NEK1,KPNA1,CDC27,RAD18,PSMD8,SAFB,TFDP1,ARAP1,H2AFX,E2F1,YWHAZ,CHEK2,BEND3,MAPK1,ANAPC4,IFI16,SMARCD1 |
| 2.796e-10 | -22.00 | establishment of protein localization to organelle | biological process | GO:0072594 | 357 | 100 | 17256 | 2622 |
POLA2,TOMM20,NUP188,MTX3,TSC2,RPLP2,VTI1A,RPAIN,RPL23A,RPL11,MOAP1,SNUPN,TIMM23,NUP107,TNPO2,NUP153,TIMM50,SRP72,LARS,RPL29,SEC61B,RPL35,NXT1,RAB7A,RPL38,NUP155,NUTF2,RPS9,RPSA,RPL37,PEX5,CHMP4A,TIMM13,HSPA4,SEC61A1,RPS27A,TIMM29,RPS14,TIMM17A,ARNTL,RPLP1,CHMP4B,KPNA2,CLU,VPS4A,SMURF1,PITRM1,RPS26,POT1,LONP2,NXT2,RPS15,RPS2,SEC61G,PHB2,RAE1,NUP54,RPL15,TIMM21,RAB11A,VPS25,RPL17,FBXO7,NABP2,H2AFY,TNPO3,RPL19,LRSAM1,STAT3,MTX2,NUP85,TGFB1,NAGPA,TIMM8B,GCC2,PPP3CA,TNFAIP3,RPL6,RPL8,RPS10,RPS24,MTX1,PTTG1IP,TOMM40,RPL27A,RPL36,MFN2,SCARB2,KPNA4,KPNA1,HGS,RPL32,PPP3R1,PML,NUP62,RUVBL2,SPCS3,SGF29,NUP58,IPO4 |
| 2.814e-10 | -21.99 | DDA1 (DET1 and DDB1 associated 1) | protein interactions | 79016 | 80 | 37 | 17029 | 2761 |
WSB2,SRM,UBE2E2,COPA,AGTRAP,DCAF15,PRKAA1,WDTC1,NANS,COPB2,DTL,PA2G4,HADHB,COPS7B,EIF5,ALDH9A1,COPS8,LARS,DCAF6,SEPT9,RBX1,LAP3,IDH3A,DCAF8,PRKDC,ADSL,LNX2,TOR1AIP2,MCM2,TARS,CAND1,DCAF11,COPS6,CFAP20,LTA4H,DCAF5,DDB1 |
| 2.878e-10 | -21.97 | SHMT2 (serine hydroxymethyltransferase 2) | protein interactions | 6472 | 437 | 122 | 17029 | 2761 |
MBD1,ZNF207,TCF12,ZNF76,HNRNPAB,TRERF1,COPA,IVNS1ABP,DYNLL1,COPE,DHX8,CUL1,NANS,EIF1B,SDHA,APP,MBD4,LIN9,CYHR1,DECR1,CLUAP1,RAB8A,BABAM2,AHCTF1,TNFAIP8,ABRAXAS2,RABGAP1L,DDA1,UBA5,CS,NOC2L,KHDC4,RNASEH2A,AQR,ATF2,PDCL3,ABCC5,CHP1,SNX8,NOL8,METTL2A,CUL3,EZR,ELP4,NUTF2,MEF2D,ARMH3,FOXRED1,RAB5B,PLEKHF2,SRSF1,IWS1,HSPA4,IDE,CHD3,LUC7L3,NT5C3B,PPM1G,CAMKMT,MYO18A,STAT1,CRCP,SPRYD4,KLHDC4,PPP5C,E2F2,COX5B,PIGN,GOLPH3L,HJURP,GSPT2,DCTN2,BABAM1,STRN4,JMJD6,PAWR,RAPGEF6,HMG20A,COPG2,NUP205,LMNA,EBP,FBXO5,HERC3,NFATC3,CCP110,HUWE1,HDAC7,PPP1R8,ARL6IP1,CTR9,ALDH18A1,STAT3,HNRNPM,LUC7L2,NIPSNAP1,HP1BP3,RHOA,NASP,DDX24,STRIP1,ABCF2,WDR18,RFXANK,MRPS10,HEBP2,BMS1,GORASP2,ARID1A,ADRB2,WDR81,C9orf40,CAND1,SEC31A,GNAS,HGS,LRPPRC,HMGB2,YWHAZ,ATP6V1C1,SNX14,ADNP2 |
| 2.885e-10 | -21.97 | MISSIAGLIA_REGULATED_BY_METHYLATION_DN | MSigDB lists | MISSIAGLIA_REGULATED_BY_METHYLATION_DN | 115 | 45 | 17377 | 2626 |
H2AFZ,HNRNPAB,FOXM1,CDT1,CENPF,RRM1,KIF23,LANCL1,STMN1,EBP,KIFC1,CDKN2C,CCNA2,DUT,MCM5,KIF14,FUT8,PRC1,ARL6IP1,KIF22,KNTC1,CENPM,RNASEH2A,FBL,DNMT1,PCBP2,MSH6,SMC4,TK1,PRKDC,ILF3,MKI67,CDC6,NUSAP1,SMC2,H2AFV,TRIM28,SNRPA,PRIM1,HMGN2,RBMX,HMGB2,SRSF3,UBE2C,ESPL1 |
| 2.939e-10 | -21.95 | GSE7509_DC_VS_MONOCYTE_WITH_FCGRIIB_STIM_UP | MSigDB lists | GSE7509_DC_VS_MONOCYTE_WITH_FCGRIIB_STIM_UP | 185 | 62 | 17377 | 2626 |
RMND5A,CCDC93,NCOR2,NAT9,GLT8D1,KLHL21,TMEM41B,WDTC1,MOGS,STARD7,CREBL2,PAWR,EZH1,MXD4,XPO7,RGS2,MAPK14,REEP5,SNAPC4,PARK7,MBD4,FARSA,ZKSCAN1,TTC3,CYB5R1,AQR,MAP3K14,SPTSSA,CTDSP2,ALDH9A1,RYBP,SAP30,HMGN1,DHX29,BTG2,PPIE,WDR18,FRAT2,UBE4B,FAM50B,PCGF1,API5,HAGH,MAN2A2,ALDH3B1,EPRS,DAP3,PDCD6,LIMK1,LUC7L3,LRPPRC,ARAP1,CEBPG,MEGF9,HMGB2,MDH1,MRFAP1L1,SCARB1,RUVBL2,CD81,PURA,GCSH |
| 2.939e-10 | -21.95 | GSE35543_IN_VITRO_ITREG_VS_CONVERTED_EX_ITREG_UP | MSigDB lists | GSE35543_IN_VITRO_ITREG_VS_CONVERTED_EX_ITREG_UP | 185 | 62 | 17377 | 2626 |
SKA3,PARP12,HJURP,FOXM1,DCAF15,POC1A,CHTF18,PTTG1,BABAM1,CENPF,DBF4,CDCA3,CDCA8,KIF23,RACGAP1,HAUS4,PMF1,FKBP2,IFT27,STMN1,MFSD10,SPAG5,FBXO5,HNRNPA2B1,NUP210,GLIS2,MCM5,SUCLG2,NDUFS8,KIF22,RBM3,CDC25B,CORO1A,CENPM,GLE1,RNF26,PACS2,TACC3,SMC4,PSRC1,PRIM2,ASPM,SUGP2,CYP20A1,MKI67,MRPS10,CKAP2L,SLBP,NUSAP1,BRCA1,PKMYT1,MASTL,POLE,BIRC5,LSM6,NRM,E2F1,WDR62,E2F2,CCNB2,UBE2C,ESPL1 |
| 2.939e-10 | -21.95 | GSE1740_MCSF_VS_MCSF_AND_IFNG_DAY2_DERIVED_MACROPHAGE_WITH_IFNA_STIM_UP | MSigDB lists | GSE1740_MCSF_VS_MCSF_AND_IFNG_DAY2_DERIVED_MACROPHAGE_WITH_IFNA_STIM_UP | 185 | 62 | 17377 | 2626 |
PWWP2A,PPCS,CDC40,ZCCHC9,KIAA0100,SHPRH,MCCC1,TKT,CERK,UBE2I,CUTC,REEP5,CHD1,BZW2,RSAD1,PAIP2,WRNIP1,EEF2K,SLC25A36,CDK5,RNFT1,UTP18,ETV6,RAB4A,TTC9C,SOCS6,AKR1B1,ACAD8,CNOT6L,TMEM14C,NUP85,MLST8,PHF10,ZNF559,RB1CC1,DHX29,EMB,PRKDC,DENND4C,ACSL3,CRNKL1,FBXO9,NUP155,NUTF2,CDC23,MEN1,H2AFV,EML4,ZDHHC3,ECH1,RPA1,DDX17,PCM1,ZNF700,VPS26B,ACOX1,DTX4,FN3KRP,IMPDH1,PKD2,MAPK1,MRPL13 |
| 2.939e-10 | -21.95 | GSE369_IFNG_KO_VS_WT_LIVER_DN | MSigDB lists | GSE369_IFNG_KO_VS_WT_LIVER_DN | 185 | 62 | 17377 | 2626 |
PPIB,MMACHC,TP53RK,NOP2,MRPS15,PHB2,PDAP1,SRSF6,ATG2B,SND1,FKBP2,SNRPD3,HAUS2,RRP36,HDDC2,MCTS1,FARSA,PDXP,DDX56,RAP1A,GATC,SLC38A5,TIMM23,CD3EAP,PPP1R8,TRMU,ZDHHC13,MECR,CS,SUCLG2,YIF1B,PCYT2,ORC3,MRPL11,TMEM160,RPAP3,RPP25,PPIF,TXNL1,AATF,ELL2,NOL8,WDR18,UBE2V1,TOMM40,ODC1,FOXRED1,USP36,AKAP1,C1orf122,GEMIN5,EPRS,TIMM13,ATP1A1,MRPL55,PFDN4,TBL3,CHCHD1,FTSJ1,CRCP,PDSS2,PDCD2L |
| 2.978e-10 | -21.93 | GO_NEGATIVE_REGULATION_OF_CELL_CYCLE_PHASE_TRANSITION | MSigDB lists | GO_NEGATIVE_REGULATION_OF_CELL_CYCLE_PHASE_TRANSITION | 139 | 51 | 17377 | 2626 |
ZNF207,GPR132,CLSPN,CENPF,CSNK2A1,SMARCA4,BLM,CCNB1,CDC73,MAD2L2,FANCI,CNOT3,RFWD3,RPA2,RB1,MDM2,PCNA,CCNA2,PTEN,CENPJ,FBXO7,GTSE1,H2AFY,BRD7,CDKN1B,BCL2,CNOT6L,CTDSP2,CARM1,CDC5L,PRPF19,PLK3,PLK1,PRKDC,BTG2,PRMT2,SOX4,MEN1,RBM38,RPS27A,E2F4,TFDP1,PML,E2F1,PKD2,CNOT6,CHEK2,TFDP2,ZNF830,CDK2,TERF1 |
| 3.064e-10 | -21.91 | PKM (pyruvate kinase M1/2) | protein interactions | 5315 | 182 | 64 | 17029 | 2761 |
USP7,SUZ12,RAF1,RAC1,CUL1,NANS,TWF2,PCBP1,APP,EPM2A,MDM2,EIF4A3,UCHL5,PPME1,PIN1,RAD23B,ATF2,CFL1,CDC37,CUL3,AURKB,BRCA1,AMDHD2,MCM2,H2AFX,FUS,ARRB2,MAPK1,PFKP,TUBB,NXT2,FUBP1,EWSR1,TKT,ETS1,CDC73,NPLOC4,WWP2,RPN1,HUWE1,PTEN,MCM5,ZNF746,BANF1,CTPS1,ANP32A,LYPLA2,EEF1D,LDHB,STAU1,TK1,FAM49B,LDHA,CAPZA2,MPG,PKM,ISG15,KPNA1,PML,PDLIM5,CD81,CDK2,TERF1,EGLN1 |
| 3.128e-10 | -21.89 | LUC7L2 (LUC7 like 2, pre-mRNA splicing factor) | protein interactions | 51631 | 174 | 62 | 17029 | 2761 |
NAT9,CDC40,IVNS1ABP,SUZ12,SRSF6,GADD45G,RBM8A,TIA1,RPL15,CSNK2A1,JMJD6,MAN2B1,THRAP3,SNRPD3,MAP1LC3B,SRRT,APP,PAIP1,PABPC4,KLHL20,HUWE1,TRA2B,RPL19,TARDBP,STAT3,HDHD2,PABPC1,LUC7L2,SRSF10,CDC37,SRPK2,RPAP3,PDPK1,SRSF11,STAU1,FTL,SNRNP200,ZCCHC10,NASP,RNPS1,CUL3,SREK1,BCLAF1,NUTF2,FXR1,LUC7L,SRSF1,CAND1,MAN2A2,SYNCRIP,NSF,HNRNPR,CHD3,CLK3,LUC7L3,UHRF2,DDX5,ZRANB2,SNRNP70,ATP6V1C1,CD81,PRPF4B |
| 3.162e-10 | -21.87 | GSE22432_MULTIPOTENT_PROGENITOR_VS_PDC_DN | MSigDB lists | GSE22432_MULTIPOTENT_PROGENITOR_VS_PDC_DN | 181 | 61 | 17377 | 2626 |
RAB14,PPCS,MUT,SCOC,PHB2,MDH2,PMS2,NKRF,SLC20A1,ANKRD26,FARSA,PSMD2,PSMD1,CCNA2,SUV39H2,TIMM23,NT5DC1,UCHL5,PPIG,EXOSC1,ATP13A3,NUP107,DDX31,GLE1,CHTOP,SPTSSA,ALDH18A1,NUP85,STRAP,DVL2,PDLIM2,SNX8,TDP1,PIGT,RAD51AP1,PPP1R21,ADSL,ABHD11,PITPNB,TAZ,LUC7L,STK17B,TRIM28,TARS,CLNS1A,MRPL2,TIMM13,GOLGA7,POLE,TTLL4,TATDN2,ACOX1,CEP55,PPM1G,IARS2,ATE1,ACAT1,SSNA1,PPP5C,PITRM1,GCSH |
| 3.162e-10 | -21.87 | ZHANG_TLX_TARGETS_36HR_DN | MSigDB lists | ZHANG_TLX_TARGETS_36HR_DN | 181 | 61 | 17377 | 2626 |
ZNF207,DNAJC2,ASH1L,FAM208B,MCM10,MPHOSPH8,DEPDC1,SUZ12,CENPF,TPX2,KIF23,SMC6,BLM,NCAPG,TCF19,CHD1,FANCI,SPAG5,DTL,LYAR,SMC3,CCNA2,SUV39H2,PPIG,PRC1,TIMELESS,UPF2,TARDBP,SLC12A2,NUP85,SMC4,GINS1,NASP,HMGN5,NET1,RAD51AP1,TUBGCP5,MKI67,WDHD1,NUSAP1,BCLAF1,BRCA1,SMC2,ANLN,SHCBP1,KIF11,MACF1,SRSF1,PRIM1,MASTL,KIF2A,RAD51C,KPNA4,PCM1,KIF18A,POLE,RBL1,CEP55,ROCK1,SASS6,PRPF4B |
| 3.193e-10 | -21.86 | ZAMORA_NOS2_TARGETS_UP | MSigDB lists | ZAMORA_NOS2_TARGETS_UP | 64 | 31 | 17377 | 2626 |
MIF,SRM,IER2,HSPH1,RPL29,IFRD1,H2AFZ,RHOA,CSRP1,RAC1,RRM1,PCSK7,DNAJB1,MCM2,STMN1,STAM,RPSA,PABPC4,GTF2F1,PCNA,SMAD2,MCM5,ACLY,PDCD2,HMGB2,ATP6V1C1,CDK2,YWHAH,PPA1,TUBB,DCTN1 |
| 3.226e-10 | -21.85 | ZC3H18 (zinc finger CCCH-type containing 18) | protein interactions | 124245 | 131 | 51 | 17029 | 2761 |
PRPF38B,MZT1,CDC40,ZCCHC8,XAB2,TWNK,GSPT2,USP39,SRRT,FERMT3,CCNA2,PPIG,BUD31,CTR9,AQR,CPSF4,RBM15,LUC7L2,TERF2,SRSF10,HP1BP3,CDC5L,RBM15B,SRPK2,YTHDC1,BRD4,PPIE,SF3B6,RPL6,SMU1,RNPS1,CUL3,CRNKL1,USP10,RTF1,KRAS,TOPORS,LUC7L,SLTM,SF3A2,SRSF1,SUPT16H,KEAP1,UPF1,RBM25,CLK3,SAFB,RBMX,TERF1,SSRP1,PRPF4B |
| 3.238e-10 | -21.85 | OSMAN_BLADDER_CANCER_UP | MSigDB lists | OSMAN_BLADDER_CANCER_UP | 379 | 104 | 17377 | 2626 |
TMED7,RAB14,SARNP,PNISR,SF3B1,ACTR3,GLUD1,ABCB10,TGOLN2,LACTB2,UBQLN2,KTN1,CPNE3,SLC25A37,FBXO22,MBD4,ASPHD2,PRNP,ZER1,PCNA,JAZF1,SLC44A1,RAD23B,SLC26A2,RBM12B,EIF5,MOB1A,FGFR1OP2,WDR41,SAP30,CDC5L,ENPP4,SRP72,FAM172A,PGGT1B,ATXN1,BICD2,AZI2,ALDH3B1,HIPK2,RBMS1,CCDC125,XRCC4,NMD3,ZMAT3,TMEM33,NXT2,RECQL,GCLM,GOLIM4,EWSR1,NDUFS1,TM9SF4,AGTRAP,ZNF316,SESTD1,PDAP1,SECISBP2,BLM,CSNK1A1,SLC25A36,VASP,SMC3,MEX3C,SLC1A4,INPP5A,BRD7,FOXN2,TNPO3,H2AFY,TTC17,CITED2,LDLRAD3,TMX1,SRSF11,EIF5A,TGFB1,LONRF3,TSPAN31,OXR1,USP42,PARP4,LDHA,RFXANK,MRPS10,FBXO9,FAM133B,BCLAF1,FXR1,APPL1,TTC33,ADSS,SCARB2,ATP6V1D,SYNCRIP,MAGT1,PRPS2,BBX,YY1,BRWD3,RPS6KC1,PDLIM5,TOB1,NUDT3 |
| 3.358e-10 | -21.81 | GO_SINGLE_STRANDED_DNA_BINDING | MSigDB lists | GO_SINGLE_STRANDED_DNA_BINDING | 78 | 35 | 17377 | 2626 |
MCM10,PMS2,BLM,PCBP1,PARK7,RAD23A,TERF2IP,HNRNPA2B1,RPA2,SUB1,SSBP3,RAD23B,XRCC2,MSH2,YBX1,CRY2,TERF2,TDP1,ERCC1,POLR2G,RAD51AP1,POLR2D,RTF1,RPA1,RAD51C,NEIL3,LRPPRC,RBMS1,XRCC3,HMGB2,TERF1,PURA,POT1,RAD51D,FUBP1 |
| 3.359e-10 | -21.81 | SNRNP70 (small nuclear ribonucleoprotein U1 subunit 70) | protein interactions | 6625 | 207 | 70 | 17029 | 2761 |
CHERP,SUZ12,CUL1,CSNK2A1,SNRPD3,APP,HNRNPA2B1,STRBP,EIF4A3,TRA2B,CEP63,SRSF10,CDC5L,PRPF19,SRPK2,SNRNP200,VHL,SNRPB,CRNKL1,RNPS1,CUL3,DDX20,PRPF3,MRPS14,LUC7L,GAR1,SRSF1,DDX17,GEMIN5,DAP3,SMAD2,HNRNPR,CLK3,XRCC3,SNRPG,COPS6,SMAD1,CCDC59,SMAD4,HDAC2,GEMIN7,CCDC137,CTDP1,MRPS26,ARGLU1,THRAP3,CMTR2,GEMIN6,GEMIN4,PABPC1,LUC7L2,TERF2,SRSF11,YTHDC1,PRRC2A,ILF3,MRPS10,BCLAF1,KIF11,SF3A2,MATR3,SLTM,SNRPA,CAND1,UPF1,SYNCRIP,RBMX,ZRANB2,SRSF3,HNRNPDL |
| 3.392e-10 | -21.80 | GSE13547_CTRL_VS_ANTI_IGM_STIM_BCELL_12H_UP | MSigDB lists | GSE13547_CTRL_VS_ANTI_IGM_STIM_BCELL_12H_UP | 177 | 60 | 17377 | 2626 |
CLSPN,KDM4A,CENPF,CDCA3,RRM1,CDCA8,TPX2,KIF23,RACGAP1,NUF2,PMF1,FKBP2,TCF19,NCAPG,STMN1,REEP5,SPAG5,FBXO5,CCNA2,RINL,DUT,MCM5,KIF14,PRC1,PPP6C,GNAI2,MYBL1,MYO5A,TACC3,GINS1,PLK1,RFC3,TK1,ASPM,PBK,RAD51AP1,CPOX,MKI67,KIF15,RRM2,WDHD1,CDC6,AURKB,BRCA1,SMC2,SHCBP1,KIF11,ASF1B,PRIM1,POLE,BIRC5,NEIL3,TFDP1,CEP55,HMGB2,FKBP5,ANP32E,WDR76,NDE1,CCNB2 |
| 3.392e-10 | -21.80 | GSE3982_EOSINOPHIL_VS_BASOPHIL_DN | MSigDB lists | GSE3982_EOSINOPHIL_VS_BASOPHIL_DN | 177 | 60 | 17377 | 2626 |
DDX58,CMAS,GGNBP2,RWDD1,NF1,EIF3D,VAV2,CTCF,SLC4A2,XPO7,METTL3,MEAF6,PSMD1,ADD3,FUT8,TPST1,SRI,HADHB,MRPL34,INTS12,SUCLG2,RPN2,TARDBP,CEP63,PIKFYVE,SAP30L,SMC4,ABCC5,NIPSNAP1,VPS13B,MAP4K4,UBE4B,ESYT1,CBFB,PEF1,SLTM,FKBP3,PRDX1,OPTN,STOML2,RPL36,DTWD1,RPL37,NSA2,DNAJC10,DAP3,PPP2R5A,WDR11,JAK1,STK38,ACOX1,IARS2,RNF38,PKD2,COPS6,RRS1,LTA4H,FAM208A,RNF139,MRPL3 |
| 3.392e-10 | -21.80 | GSE17721_POLYIC_VS_GARDIQUIMOD_16H_BMDC_DN | MSigDB lists | GSE17721_POLYIC_VS_GARDIQUIMOD_16H_BMDC_DN | 177 | 60 | 17377 | 2626 |
NDUFV2,KIAA0100,CKLF,RPLP2,GORASP1,SEC61G,DAP,VTI1A,MEF2A,NDUFA4,ABCB10,CDC42SE2,C2orf49,XPR1,CD320,BCAT2,SEC11A,LYAR,PA2G4,ATP6V0B,UBXN2A,FBXL6,CWC27,DAD1,PTPN11,CAPZA1,ANXA5,PTGES3,MRPL48,HDHD2,SRSF10,FAM118B,SIGMAR1,FOPNL,TEX10,RDH10,RPL38,DNAJC9,DCUN1D5,MTX1,MRPS14,MAPK3,SRSF1,STOML2,ADSS,ALG3,UTP20,PON2,NUCB1,TTC13,ACOX1,PGRMC1,ACADM,COPS6,TAF6,CHID1,SSSCA1,BYSL,PDF,TMEM33 |
| 3.393e-10 | -21.80 | Protein processing in endoplasmic reticulum | KEGG pathways | ko04141 | 165 | 59 | 7161 | 1149 |
UBE2D3,HSPH1,ATXN3,DNAJC5,PRKCSH,SEC61G,DNAJB2,MOGS,CUL1,DNAJB1,EIF2AK4,UBQLN2,BCAP31,NPLOC4,MAN1A1,RAD23A,SSR1,CAPN2,RPN1,SAR1A,DAD1,SEC24C,RRBP1,RAD23B,NSFL1C,RPN2,BCL2,LMAN1,PDIA6,RNF5,PREB,BAK1,UBQLN4,SEC61B,RBX1,MAN1B1,ERO1A,SSR2,EIF2AK1,UBE4B,DNAJA1,SYVN1,EDEM2,HSPA1B,DERL1,SEC31A,DNAJC10,HSPBP1,PLAA,SEC61A1,DDOST,STT3A,SEL1L,SIL1,ATF6,MAP3K5,NGLY1,CAPN1,SVIP |
| 3.393e-10 | -21.80 | Protein processing in endoplasmic reticulum | KEGG pathways | hsa04141 | 165 | 59 | 7161 | 1149 |
UBE2D3,HSPH1,ATXN3,DNAJC5,PRKCSH,SEC61G,DNAJB2,MOGS,CUL1,DNAJB1,EIF2AK4,UBQLN2,BCAP31,NPLOC4,MAN1A1,RAD23A,SSR1,CAPN2,RPN1,SAR1A,DAD1,SEC24C,RRBP1,RAD23B,NSFL1C,RPN2,BCL2,LMAN1,PDIA6,RNF5,PREB,BAK1,UBQLN4,SEC61B,RBX1,MAN1B1,ERO1A,SSR2,EIF2AK1,UBE4B,DNAJA1,SYVN1,EDEM2,HSPA1B,DERL1,SEC31A,DNAJC10,HSPBP1,PLAA,SEC61A1,DDOST,STT3A,SEL1L,SIL1,ATF6,MAP3K5,NGLY1,CAPN1,SVIP |
| 3.482e-10 | -21.78 | GSE22886_CTRL_VS_LPS_24H_DC_UP | MSigDB lists | GSE22886_CTRL_VS_LPS_24H_DC_UP | 190 | 63 | 17377 | 2626 |
COMMD10,CDC40,RPLP2,UQCR10,NACA,CERK,NDUFA4,EBNA1BP2,TOP2B,AP1B1,CDIPT,SLC12A9,MAPK14,PABPC4,PCYOX1L,CDK5,C12orf10,RAP1A,NDUFV1,GOT2,BDH1,GEMIN6,FBXW2,SUCLG2,GPD1L,DNMT1,PABPC1,IMPA2,ADCY7,PDLIM2,CYFIP1,EIF3L,MLEC,TACC1,RAB7A,FRAT2,RCOR1,ESYT1,TMEM147,CAPZA2,BICD2,NDUFB1,CBFB,ZMYM3,GNAS,EIF3K,HHEX,TRAM2,PON2,RPS14,EIF2D,COX8A,SLC16A1,UQCRH,TRIM32,CHEK2,ZBTB11,CHPT1,PTDSS1,RTN3,MRPL3,DEF6,EGLN1 |
| 3.494e-10 | -21.77 | PRKN (parkin RBR E3 ubiquitin protein ligase) | protein interactions | 5071 | 415 | 117 | 17029 | 2761 |
SART1,UBE2E2,DDX47,ATXN3,TXN,MRPS15,PRKCSH,MDH2,PTTG1,RAC1,RBM8A,CUL1,BCL2L1,CCNB1,BECN1,APP,PARK7,RPL23A,RAD23A,CDK5,HNRNPA2B1,PCNA,PSMD1,PSMA6,RAD23B,MRPS27,HADHB,PDCD2,TARDBP,MAVS,CYB5R1,PDIA6,HTRA2,PRPF19,PLK1,CCT2,SNRNP200,RAB7A,MRPL12,VDAC2,CIRBP,PSMB7,HNRNPF,MCL1,UBE2V1,AURKB,DNAJA1,VDAC1,SLC25A5,SRSF1,OPTN,STOML2,DDX17,AFDN,CHCHD3,DAP3,HSPA4,HNRNPR,RPS27A,PSMD8,LIMK1,RPS14,PSMD3,CEP55,ACTB,FUS,ARRB2,MAPK1,PSMC1,TUBB,FUBP1,UBE2D3,RPS2,NACA,DNAJB1,RGS2,PSMD9,TFRC,LMNA,NDUFS4,HOMER1,PSMD2,FBXO7,ZNF746,BCL2,PCYT2,UBE2M,HNRNPM,SLC25A1,NIPSNAP1,NTPCR,RPL6,TUFM,GBA,RPL8,PSMA1,ATP5MF,TOMM40,RHOT1,RHOT2,MATR3,PSMB3,PRDX1,PSMC4,CBX3,MFN2,SYNCRIP,BIRC5,HNRNPH3,LRPPRC,MDH1,DDX5,RUVBL2,ATP5F1A,SRSF3,YWHAH,HNRNPDL |
| 3.604e-10 | -21.74 | establishment of organelle localization | biological process | GO:0051656 | 402 | 109 | 17256 | 2622 |
CHMP2A,PDCD6IP,RAB11B,ACTR3,AP3M2,MYH9,NUF2,KIF2C,CCNB1,LYN,SEC16A,BECN1,MIS12,ANKRD28,KIFC1,CDK5,ANKLE1,CDC42,AP3S2,KIF14,PPP6C,DNM2,KIF22,LMAN1,TFG,SEH1L,DCTN1,USO1,PSRC1,CUL3,EZR,NUSAP1,BICD2,MCFD2,RAB1A,CHMP2B,CDC23,PEF1,TMEM201,HHEX,CHMP4A,TMED10,MAP4,CEP55,CHMP4B,VPS4A,RRS1,CLN3,NMD3,CSNK1D,STARD3NL,RPS15,KIF3B,DNAJC5,GORASP1,CDT1,CENPF,DCTN2,TRAK1,CDCA8,KIF23,RAB6A,SPDL1,AP3S1,PSEN1,RAB11A,COPG2,SPAG5,SAPCD2,PIP5K1C,KIF5B,CD59,PDCD10,RIMS3,SEC24C,ARHGEF2,KIFAP3,MCPH1,PPP6R1,SYTL3,MYO5A,TMED2,PREB,TRAPPC9,RHOT1,RHOT2,LEMD2,SEC31A,SEC23IP,KIF18A,PCM1,PDCD6,GOLGA2,NSF,SNAP29,SNAP23,CDCA5,LRPPRC,FAM83D,EXOC4,NUP62,YWHAZ,NDE1,PPP6R3,CHMP7,ESPL1,TERF1,UNC13C,SNAPIN |
| 3.668e-10 | -21.73 | SNIP1 (Smad nuclear interacting protein 1) | protein interactions | 79753 | 91 | 40 | 17029 | 2761 |
WSB2,MAX,CDC40,TMEM184B,CHERP,SF3B1,SRSF6,DHX8,THRAP3,UBE2I,SRRT,FERMT3,SP100,EIF4A3,PPIG,GMEB1,BUD31,TRA2B,AQR,DVL2,SRSF10,SRPK2,YTHDC1,ZCCHC10,ZMYM5,PPIE,RNPS1,CRNKL1,BCLAF1,TOPORS,PRPF3,SRSF1,SMAD2,CLK3,MFAP1,PIAS2,SMAD1,HIPK3,SMAD4,FAF1 |
| 3.686e-10 | -21.72 | REACTOME_METABOLISM_OF_PROTEINS | MSigDB lists | REACTOME_METABOLISM_OF_PROTEINS | 414 | 111 | 17377 | 2626 |
PIGM,TOMM20,GNPNAT1,RPLP2,PRKCSH,PIGQ,EIF3D,MOGS,RPL11,SSR1,RPL23A,SEC11A,CS,FBXW2,RPN2,LMAN1,EIF5,MGAT5,TIMM50,SRP72,CCT2,RPL29,RPL35,SEC61B,DPM1,RPL38,SUMF2,GALNT7,MCFD2,EDEM2,VDAC1,TAZ,GFER,EIF3G,RPS9,RPSA,EIF3H,EIF3A,RPL37,EIF3K,ALG3,TIMM13,SEC61A1,DDOST,STT3A,RPS27A,TIMM17A,RPS14,RPLP1,ACTB,ST3GAL2,GALNT10,USP11,B4GALT3,FAU,FBXL3,RPS26,LONP2,B4GALT2,RPS15,PIGN,RPS2,SEC61G,DHPS,B4GALT5,GSPT2,SLC25A12,B4GALT1,RPL15,SUMF1,B4GALT4,MAN1A1,C1GALT1,RPN1,EIF2S2,RPL17,DAD1,SEC24C,FUT8,PIGG,RPL19,CYC1,ST8SIA2,PABPC1,MTX2,EEF1D,PREB,EIF5A,TIMM8B,MLEC,PIGT,MAN1B1,RPL8,RPL6,RPS10,SSR2,RPS24,MTX1,TOMM40,VKORC1,RPL27A,EIF4H,ARSK,CCT8,RPL36,SEC31A,PFDN5,GALNT2,RPL32,PFDN4,SPCS3 |
| 3.706e-10 | -21.72 | GO_REGULATION_OF_CELLULAR_AMIDE_METABOLIC_PROCESS | MSigDB lists | GO_REGULATION_OF_CELLULAR_AMIDE_METABOLIC_PROCESS | 327 | 93 | 17377 | 2626 |
SARNP,RPS6KA1,PPP1R15B,FAM129A,EIF3D,RBM8A,EIF1B,RBM4,APP,PAIP1,PAIP2,HNRNPA2B1,PA2G4,IARS,EIF4A3,METTL14,EIF5,MTPN,LARS,POLR2G,NCK1,CDC123,AKT2,BTG2,CIRBP,RPL38,POLR2D,PRKRA,SOX4,EIF3G,SERP1,RPS9,EIF3H,EIF3A,EIF3K,MKNK1,SMAD2,EIF4ENIF1,TMED10,HNRNPR,DGCR8,RPS14,IARS2,CLU,SMAD1,MAPK1,NCOR2,UNK,MIF4GD,PRKAA1,TIA1,SECISBP2,EIF2AK4,RGS2,FOXO3,METTL3,SRRT,CNOT3,GATC,DAPK1,RBM3,GLE1,CNOT6L,STAT3,PABPC1,NSUN4,TGFB1,EIF5A,EIF3L,ILF3,EIF2AK1,EIF2A,FXR1,EIF4H,EIF4G2,ABCF1,PICALM,DAPK3,MAPK3,EPRS,TSC1,UPF1,SYNCRIP,PML,LRPPRC,SAMD8,CNOT6,DTD1,PGAM1,RNF139,TOB1,PURA,CPEB2 |
| 3.766e-10 | -21.70 | GSE19825_CD24LOW_VS_IL2RA_HIGH_DAY3_EFF_CD8_TCELL_DN | MSigDB lists | GSE19825_CD24LOW_VS_IL2RA_HIGH_DAY3_EFF_CD8_TCELL_DN | 186 | 62 | 17377 | 2626 |
HSPH1,PIGM,MCM10,RRP15,MRPS2,SUZ12,CHTF18,TMEM41B,SECISBP2,ORC1,XPO7,WRNIP1,DTL,UTP18,ZNF639,NUP107,NAA50,DDX31,TARDBP,AHCY,TP53BP2,UBE3C,OSTC,MRPL11,GTF2H2,STRAP,PPA1,NUP85,CDK12,ALDH9A1,NUDC,PLK1,PPIF,UBQLN4,NASP,FOXK1,ERLIN1,RAD51AP1,NQO2,PBK,LRBA,NUP155,PATL1,STOML2,PRIM1,IWS1,CCDC127,BOLA3,SEC23IP,UAP1,PRDX3,HNRNPH3,NFIL3,MAPK6,WDR4,KHSRP,PRMT7,NUP62,SPCS3,ATP6V1C1,PDCD11,DYNC1LI2 |
| 3.766e-10 | -21.70 | GSE13484_12H_UNSTIM_VS_YF17D_VACCINE_STIM_PBMC_UP | MSigDB lists | GSE13484_12H_UNSTIM_VS_YF17D_VACCINE_STIM_PBMC_UP | 186 | 62 | 17377 | 2626 |
RMND5A,COMMD10,GLT8D1,PKP4,TSC22D3,NACA,CUTA,HEXB,TGOLN2,XPO7,CDIPT,GIT2,WRB,FAM8A1,PCYOX1L,NDUFA2,RPL17,UTP18,INPP5A,MTMR4,LRRC8D,IMPAD1,PPCDC,H2AFY,YBX1,TAGLN2,CEP63,SLC35A1,ATP6V0D1,PHKG2,S100A6,CSNK1G3,HP1BP3,VPS13B,RHOA,CSRP1,RB1CC1,NEK7,USP10,EIF2AK1,ABHD11,ARID1A,CDC23,SRSF1,RDH11,PI4K2A,YIF1A,TRAM2,ATP1A1,DDOST,HIPK2,EIF2D,IARS2,GLG1,SIL1,PKD2,PSAP,ZBTB11,CHPT1,MZT2B,COIL,RNF139 |
| 3.807e-10 | -21.69 | PRPF40A (pre-mRNA processing factor 40 homolog A) | protein interactions | 55660 | 191 | 66 | 17029 | 2761 |
WASF2,SART1,CHERP,SF3B1,DHX8,CUL1,CSNK2A1,UBQLN2,UBE2I,SF3B2,TERF2IP,EIF4A3,ABI1,CDK12,PCBP2,SRPK2,CCT2,UBQLN4,BRD4,ZCCHC10,HNRNPF,RNPS1,CUL3,WIPF1,LUC7L,RPS9,DHX15,WAS,HNRNPR,CHD3,U2SURP,RRS1,SMAD4,EWSR1,ZCCHC8,MECP2,DHX9,CDK13,JMJD6,PDCD7,ASXL2,RLF,RPA2,VASP,PPIG,YBX1,HNRNPM,TERF2,STAU1,CYFIP1,CYFIP2,SF3A2,CDK11A,RPA1,PTPRF,C1orf131,GALNT2,RBM25,SYNCRIP,ZHX1,NEIL3,KMT2B,DDX5,CFAP20,SNRNP70,IFI16 |
| 3.870e-10 | -21.67 | protein-containing complex disassembly | biological process | GO:0032984 | 229 | 72 | 17256 | 2622 |
CHMP2A,ARID2,MRPS15,MRPL39,SMARCA4,KIF2C,MAP1LC3B,STMN1,TWF2,MRPL19,MRPL50,KIF14,MRPS27,MRPL34,SMARCE1,MRPL32,CFL1,MRPL57,DVL2,MRPL43,MRPL12,FRAT2,LRP5,PBRM1,CHMP2B,MRPS14,SUPT16H,KIF2A,MRPL2,DAP3,MRPL55,KIF18B,AXIN1,CHCHD1,MRPL27,EIF2D,VIPAS39,DVL1,VPS4A,CLN3,MRPL13,MRPL9,LIME1,MRPL42,MRPS2,GSPT2,MRPS26,KLC1,CSNK1A1,GFM2,MCTS1,KIF5B,PELO,MRPL54,MRPL48,MRPL40,MRPL11,MRPL21,MICAL3,WDR1,MRPS10,MRPL16,ARID1A,KIF18A,NSF,SNAP29,WIPI2,CHMP7,MRPL3,SNX14,SMARCD1,SNAPIN |
| 3.890e-10 | -21.67 | IGBP1 (immunoglobulin binding protein 1) | protein interactions | 3476 | 124 | 49 | 17029 | 2761 |
MIF,NOP9,OTUD5,UNK,EWSR1,SUMO2,UBXN1,AGO2,RAC1,TKT,NENF,POMP,UBQLN2,PCBP1,STAM,APP,PABPC4,PAIP2,SRXN1,SP100,THADA,RAD23B,MEA1,PPP6C,RPAP1,TAGLN2,PDIA6,PABPC1,CAMK2G,NUDC,CCT2,PSRC1,GLO1,UBE4B,MCFD2,MBD3,CCT8,GINS4,SRSF1,PPP2CA,PDCD6,PDLIM1,DDOST,STAT6,MED15,PRDX5,STAT1,RPLP1,NUMB |
| 3.903e-10 | -21.66 | GO_PROTEIN_SUMOYLATION | MSigDB lists | GO_PROTEIN_SUMOYLATION | 112 | 44 | 17377 | 2626 |
NSMCE4A,NUP188,EYA1,RAE1,SUMO2,NUP54,CDCA8,SMC6,TOP2B,BLM,UBE2I,NUP205,PHC2,MDM2,PCNA,SMC3,NUP210,SP100,HDAC7,MTA1,NUP107,NUP153,NUP85,SENP1,SEH1L,SP3,KIAA1586,NUP155,RANGAP1,TOPORS,AURKB,NFATC2IP,BRCA1,TRIM28,RPA1,BIRC5,NSMCE2,PIAS2,PML,NUP62,XRCC4,CBX4,CDKN2A,AAAS |
| 4.087e-10 | -21.62 | AHSA1 (activator of HSP90 ATPase activity 1) | protein interactions | 10598 | 175 | 62 | 17029 | 2761 |
RPS15,RPS2,EWSR1,THRAP3,ARF1,APP,TFRC,RPL11,HNRNPA2B1,C12orf10,PSMD2,IARS,RPL17,HUWE1,ZNF746,ARHGEF1,EFTUD2,RAD23B,TTC4,PTGES3,CDC37,LDHB,PRPF19,PLK1,CCT2,EIF3L,PRKDC,RPS10,RPL6,CIRBP,LDHA,CUL3,RPL38,RABIF,BCLAF1,DNAJA1,RAB1A,MCM2,DDX39A,EIF4H,CCT8,TRIM28,EIF3G,EIF3A,PSMC4,XRCC5,UBTF,EPRS,KPNA4,ATP1A1,RPS14,RBMX,PSMD3,PPM1G,STAT1,ACLY,FKBP5,ACADM,FAU,PPP5C,NMD3,ZC3HAV1 |
| 4.091e-10 | -21.62 | PRMT1 (protein arginine methyltransferase 1) | protein interactions | 3276 | 159 | 58 | 17029 | 2761 |
CYLD,EWSR1,THOC1,WDYHV1,SUZ12,HABP4,DHX9,CERK,USF1,EIF4A3,HUWE1,MBD2,FBXO7,CTPS1,CRY2,COPS7B,CDC25B,FBL,CHTOP,RBM15,NCOA2,CARM1,TERF2,MLST8,CDC37,VHL,DCAF8,BTG2,ZMYM5,RNPS1,CUL3,ILF3,CIRBP,BCLAF1,BRCA1,MCM2,GAR1,CAND1,SYNCRIP,HNRNPR,DGCR8,CLK3,AXIN1,STAT1,ACLY,FAM83D,KPNA2,FUS,NCOA1,YY1,SNRNP70,IDH3B,CDK2,ARRB2,SMURF1,COIL,TERF1,SSSCA1 |
| 4.167e-10 | -21.60 | EEF1A1 (eukaryotic translation elongation factor 1 alpha 1) | protein interactions | 1915 | 393 | 112 | 17029 | 2761 |
SART1,IMMT,DYNLL1,RAF1,SUMO2,RAC1,CUL1,MAPK14,RBM4,PABPC4,RPL11,SSR1,RPL23A,RAD23A,MDM2,PCNA,PSMD1,PSMA6,KMT5C,EIF4A3,DUT,PIK3R2,RAD23B,CRY2,TP53BP2,PCBP2,HTRA2,CDC37,UBQLN4,NRAS,ZCCHC10,RBX1,RAB7A,CUL3,TOPORS,MCM2,RPSA,DDX17,SUPT16H,PPP2CA,BRMS1,AHNAK,SMAD2,STAT6,RPS14,AXIN1,RPLP1,PQBP1,H2AFX,UQCRH,ACTB,FUS,ARRB2,SMURF1,SMAD4,PFKP,TUBB,UNK,NIFK,RPS2,MRPL42,GADD45G,STRN4,RPL15,THRAP3,ATP5F1B,CDC73,TUBGCP2,RPA2,GART,MEX3C,RPL17,MCM5,AHSA1,EFTUD2,RTCB,NABP2,YBX1,RBM3,MAP3K14,FBL,TTLL12,PABPC1,EEF1D,ABCC1,TXNL1,SRSF11,STAU1,TK1,TSTA3,RPL6,ILF3,RPS24,KRAS,GORASP2,ADRB2,PKM,PICALM,SNRPA,NEU1,POLR2A,RPA1,FAS,CAND1,MAGED2,RBMX,ACAT1,RUVBL2,CDK2,CD81,ECPAS,HNRNPDL |
| 4.189e-10 | -21.59 | microtubule cytoskeleton organization involved in mitosis | biological process | GO:1902850 | 104 | 42 | 17256 | 2622 |
BCCIP,ZNF207,KIF3B,MZT1,MECP2,POC1A,DCTN2,XIAP,TPX2,KIF23,RACGAP1,NUF2,CCNB1,SPDL1,STMN1,RAB11A,BIRC2,TUBGCP2,SAPCD2,KIFC1,ABRAXAS2,PRC1,ARHGEF2,MCPH1,TACC3,DCTN1,RHOA,BIRC3,INTS13,MYBL2,TUBGCP5,NUSAP1,AURKB,KIF11,KIF2A,GOLGA2,BIRC5,MAP4,CHEK2,WDR62,NDE1,ESPL1 |
| 4.215e-10 | -21.59 | autophagy | biological process | GO:0006914 | 261 | 79 | 17256 | 2622 |
CHMP2A,PRKAB1,TOMM20,DYNLL1,VTI1A,CSNK2A1,SIRT2,UBQLN2,MAP1LC3B,BECN1,STAM,PARK7,RAB8A,UBXN2A,RAB35,ATG3,NSFL1C,CISD2,DRAM2,WDR41,UBQLN4,ULK3,ATG9A,RAB7A,SUPT20H,RAB1A,CHMP2B,VDAC1,TOLLIP,PLEKHF2,OPTN,TBC1D17,CHMP4A,RAB24,RPS27A,UBXN2B,TOMM6,VIPAS39,CHMP4B,STK11,CLU,VPS4A,CLN3,SMURF1,USP13,PHF23,DAP,PRKAA1,RAB23,ATG2B,PSEN1,VPS25,ATG4A,TIGAR,VMP1,FBXO7,EI24,ATG13,LRSAM1,PACS2,RB1CC1,GBA,USP10,WDR81,TOMM40,MARK2,RMC1,SH3GLB1,TFEB,MFN2,MTMR3,HGS,PLAA,SNAP29,WIPI2,WDR45B,SNX14,IFI16,SNAPIN |
| 4.215e-10 | -21.59 | process utilizing autophagic mechanism | biological process | GO:0061919 | 261 | 79 | 17256 | 2622 |
CHMP2A,PRKAB1,TOMM20,DYNLL1,VTI1A,CSNK2A1,SIRT2,UBQLN2,MAP1LC3B,BECN1,STAM,PARK7,RAB8A,UBXN2A,RAB35,ATG3,NSFL1C,CISD2,DRAM2,WDR41,UBQLN4,ULK3,ATG9A,RAB7A,SUPT20H,RAB1A,CHMP2B,VDAC1,TOLLIP,PLEKHF2,OPTN,TBC1D17,CHMP4A,RAB24,RPS27A,UBXN2B,TOMM6,VIPAS39,CHMP4B,STK11,CLU,VPS4A,CLN3,SMURF1,USP13,PHF23,DAP,PRKAA1,RAB23,ATG2B,PSEN1,VPS25,ATG4A,TIGAR,VMP1,FBXO7,EI24,ATG13,LRSAM1,PACS2,RB1CC1,GBA,USP10,WDR81,TOMM40,MARK2,RMC1,SH3GLB1,TFEB,MFN2,MTMR3,HGS,PLAA,SNAP29,WIPI2,WDR45B,SNX14,IFI16,SNAPIN |
| 4.260e-10 | -21.58 | HSP90AB1 (heat shock protein 90 alpha family class B member 1) | protein interactions | 3326 | 325 | 97 | 17029 | 2761 |
NPHP4,CYLD,IVNS1ABP,RPS6KA1,SUMO2,MYH9,CUL1,CSNK2A1,NANS,ATP6V1B2,PRKACA,PCBP1,CDK5,MDM2,PSMD1,SHC1,NUP107,HADHB,CRY2,TTC4,CDC37,CDC5L,CCT2,TRIM8,CUL3,AURKB,BRCA1,MCM2,RPSA,EIF3H,STOML2,MKNK1,HSPA4,DDOST,CLK3,CAMKMT,STAT1,IARS2,STK11,KPNA2,XRCC3,FKBP5,FUS,PPP5C,ARRB2,RPS26,POT1,TUBB,HSPH1,UNK,RPS2,MAPRE1,DCTN2,PRKAA1,CDK13,ATP5F1B,IP6K2,CDC73,TUBGCP2,C12orf10,FGFR3,CLIC4,GRK2,PTEN,HUWE1,RPL17,MCM5,AHSA1,ZNF746,PTGES3,MAP3K14,MVP,GNAI2,STAT3,NUP85,SPTAN1,RPAP3,DDX24,PRKDC,LDHA,RPL6,PKM,METTL22,CDK11A,ISG15,CAND1,MAGED2,KEAP1,RPL32,MAPK6,MDH1,ATP5F1A,PPP6R3,CDK2,TERF1,CDKN2A,EGLN1 |
| 4.307e-10 | -21.57 | CDH1 (cadherin 1) | protein interactions | 999 | 641 | 164 | 17029 | 2761 |
ADD1,LUZP1,CSNK2A1,EBNA1BP2,AGFG1,SND1,PARK7,RPL23A,DST,DLG5,CDC42,IL6ST,EIF5,LRRC59,CARMIL1,PCBP2,USO1,SEPT9,NCK1,EZR,RRM2,ARHGDIB,BRCA1,ESYT1,ANLN,EPB41,RPL37,AHNAK,MAP4,ITGB1,SH3GLB2,ATXN2L,ADAM9,RPS26,PFKP,HDAC2,NUMB,MAPRE1,NKD2,RPL15,DNAJB1,NOTCH2,PSEN1,PDXDC1,COPG2,LMNA,VASP,ATIC,CAPZA1,TENM3,SLC12A2,EEF1D,NIPSNAP1,EIF5A,RB1CC1,DHX29,RPL6,C1orf35,GORASP2,PLEC,EIF2A,SEPT7,PKM,EIF4H,EIF4G2,CCT8,XRCC5,PTPRF,PDLIM1,GOLGA2,CDC27,SNAP23,VCPIP1,YWHAZ,EHD4,NIPSNAP2,PDLIM5,CCNB2,ZC3HAV1,EXOC3,WASF2,PPP1R37,RAB11B,CAST,ACTR3,ANK3,OLA1,MYH9,TWF2,PCBP1,KTN1,CRKL,MDM2,PPME1,ADCY9,NSFL1C,ANAPC7,MAVS,TP53BP2,ABI1,GM2A,RPL29,PPP1R18,ELP4,ERBIN,CHMP2B,TANC1,RAB1A,ERC1,GLOD4,AFDN,STK38,STAT1,CANT1,CHMP4B,SCARB1,PARD3,TUBB,CSNK1D,RPS2,PKP4,PDAP1,SCYL1,FLOT1,CDCA3,ARFIP2,CBLL1,ARGLU1,CSNK1A1,BZW2,SCYL2,PIP5K1C,KIF5B,ADD3,PTEN,AHSA1,H2AFY,TAGLN2,CNN2,LYPLA2,NUDC,SPTAN1,ADAM17,SNX2,DENND4C,LDHA,ARHGEF12,RANGAP1,MACF1,PICALM,MARK2,CIP2A,SH3GLB1,PRDX1,TPD52L2,GNA12,KEAP1,FAM110A,SNAP29,E2F1,FAM126A,IGBP1,ARHGAP23,ESYT2 |
| 4.315e-10 | -21.56 | GO_POSITIVE_REGULATION_OF_CHROMOSOME_SEGREGATION | MSigDB lists | GO_POSITIVE_REGULATION_OF_CHROMOSOME_SEGREGATION | 23 | 17 | 17377 | 2626 |
PLK1,RB1,GOLGA2,RAD18,PTEN,GORASP1,NSMCE2,CUL3,SMC6,H2AFY,CDC6,SIRT2,CCNB1,RAB1A,BECN1,ESPL1,FBXO5 |
| 4.372e-10 | -21.55 | GSE37532_WT_VS_PPARG_KO_VISCERAL_ADIPOSE_TISSUE_TREG_UP | MSigDB lists | GSE37532_WT_VS_PPARG_KO_VISCERAL_ADIPOSE_TISSUE_TREG_UP | 178 | 60 | 17377 | 2626 |
SARNP,DEPDC1,POC1A,TCF3,DCTN2,TPX2,RRM1,CDCA8,CTCF,KIF2C,STMN1,FANCI,SPAG5,FBXO5,CALM2,HNRNPA2B1,SAP130,OIP5,CDKN2C,CLIC4,CENPJ,KIF14,DUT,PPP6C,PRC1,GTSE1,CDC25B,TCEA1,NAP1L4,RNF26,CGGBP1,TACC3,HNRNPM,TERF2,HP1BP3,FOPNL,CCDC34,EZR,CKAP2L,SLBP,NUSAP1,RANGAP1,PKMYT1,CCNF,H2AFV,HMGN2,HAUS8,KIF18A,PEX5,CDC27,BIRC5,ZNF367,NRM,CDCA5,H2AFX,HMGB2,KPNA2,YWHAZ,E2F2,ESPL1 |
| 4.439e-10 | -21.54 | GSE24634_TEFF_VS_TCONV_DAY7_IN_CULTURE_UP | MSigDB lists | GSE24634_TEFF_VS_TCONV_DAY7_IN_CULTURE_UP | 191 | 63 | 17377 | 2626 |
POLA2,FGFR1OP,HJURP,CDT1,CENPF,PTTG1,OLA1,CDCA8,TPX2,SMC6,RACGAP1,PXMP2,KIF2C,BLM,CCNB1,PPP1R16B,NCAPG,STMN1,FANCI,ATG4A,CAPN2,FASTKD3,DTL,OIP5,PCNA,CCNA2,FUT8,PRC1,TIMELESS,KIF22,CLDND1,KNTC1,CENPM,MRPL11,TACC3,PLK1,TDP1,RFC3,TK1,ASPM,RAD51AP1,SELPLG,KIF15,RRM2,EZR,NUSAP1,MCM2,KIF11,PRIM1,NEIL3,TFDP1,CEP55,PPM1G,HMGB2,PIEZO1,UBE2C,CCNB2,TSPAN5,ESPL1,FAF1,DEF6,ZBTB24,POLQ |
| 4.439e-10 | -21.54 | GSE339_CD4POS_VS_CD8POS_DC_IN_CULTURE_DN | MSigDB lists | GSE339_CD4POS_VS_CD8POS_DC_IN_CULTURE_DN | 191 | 63 | 17377 | 2626 |
SRM,PPIB,PRKCSH,SEC61G,UQCR10,TOR3A,TAP1,DLGAP4,MOGS,PLXNA1,AP3S1,RAB11A,EXT2,SRRT,LMNA,DTL,MDM2,NEK6,TNFAIP8,THAP4,RNASEK,PPP1R12C,AP1M1,H2AFY,MRPL54,FBXW2,ANXA5,KIFAP3,TAP2,CNN2,CYC1,LPCAT1,PABPC1,CDC37,KAT2A,POLR2L,ERF,NET1,RAB7A,MAN1B1,VDAC2,NDUFA7,CADM1,ESYT1,LY6E,ODC1,SPPL2B,PI4K2A,RPL37,PEX5,MID1IP1,SERF2,HINT1,TWSG1,PML,LY75,NDUFS5,PSAP,SCARB1,CD81,RPS26,HIGD2A,NUMB |
| 4.485e-10 | -21.53 | organelle fission | biological process | GO:0048285 | 317 | 91 | 17256 | 2622 |
BCCIP,ZNF207,CHMP2A,NDC1,PDCD6IP,UBR2,PTTG1,ACTR3,XIAP,TPX2,NUF2,KIF2C,CCNB1,BECN1,BIRC2,MIS12,MIEF1,KIFC1,ANKLE1,MTFR1L,ABRAXAS2,KIF14,AKAP8,XRCC2,DNM2,PDS5B,KIF22,CDC25B,MYBL1,SEH1L,PLK1,MND1,PSRC1,BIRC3,CUL3,TUBGCP5,NUSAP1,SMC2,AURKB,CHMP2B,CDC23,RAD54B,KIF2A,RAD51C,CHMP4A,DSN1,KIF18B,CEP55,XRCC3,CHMP4B,CHEK2,VPS4A,RRS1,PPP2R2D,RAD51D,KIF3B,CTDP1,MZT1,PHF23,CDT1,CDCA8,KIF23,TOP2B,RACGAP1,SPDL1,NCAPG,RAB11A,TUBGCP2,SPAG5,FBXO5,RB1,PRC1,NAA50,SMC4,RHOA,ASPM,MTFR2,MYBL2,KIF11,MASTL,LEMD2,KIF18A,GOLGA2,BIRC5,CDCA5,NUP62,NDE1,UBE2C,CHMP7,ESPL1,TERF1 |
| 4.542e-10 | -21.51 | GO_KINASE_BINDING | MSigDB lists | GO_KINASE_BINDING | 587 | 145 | 17377 | 2626 |
FGFR1OP,ADAM10,PRKCSH,CCNL2,CCNB1,PARK7,CALM2,CDK5,CDKN2C,USF1,RAB8A,PCNA,NEK6,CDC42,DPYSL2,PIK3R2,FIZ1,PPP1R12C,DNM2,CDC25B,PTPRK,CDC37,CDC5L,PLK1,NCK1,AKT2,EZR,CDC6,PRPSAP1,RHEB,WAS,AXIN1,ITGB1,CAB39,ADAM9,CHEK2,DVL1,SMAD1,ARRB2,SLC12A7,PPP1R12A,PRKAA1,CIB1,B4GALT1,MEF2A,RACGAP1,TOP2B,PARN,RB1,HDAC7,KIF13B,FBXO7,MSH2,PIK3IP1,MVP,MAML1,SOCS5,RB1CC1,ACSL3,APPL1,AKAP1,FAS,FNTA,GOLGA2,NSF,DUSP3,CSK,FAM83D,YWHAZ,MAP3K5,PDLIM5,TOB1,CDKN2A,PRKAB1,CYLD,FOXM1,RAF1,SLC2A1,RAC1,TPX2,BCL2L1,AP1B1,TWF2,GLRX3,PRKACA,CPNE3,CCNA2,SHC1,SP100,TBC1D14,KIF14,PIN1,PPME1,MAVS,ATF2,DVL2,VDAC1,TOLLIP,ATP1A1,PPP2R5A,HINT1,STK38,SAFB,TICAM1,MAPK1,ZC3HC1,TCF3,PAWR,FOXO3,MAD2L2,JAKMIP1,FBXO5,CCNK,PTPN2,ADD3,PDCD10,PTEN,CENPJ,AXIN2,PRC1,PTPN11,ANXA5,H2AFY,ATG13,STAT3,LDHB,PDPK1,MOB4,TELO2,TNFAIP3,PRKAR1B,JTB,LDHA,RFFL,KCNQ1,PDE3B,KIF11,BORA,CACNB1,PRDX3,MAPK6,E2F1,IGBP1,PGAM1,FAF1 |
| 4.567e-10 | -21.51 | breast-carcinoma-ductal_carcinoma | COSMIC cancer mutations | breast-carcinoma-ductal_carcinoma | 15245 | 2360 | 17385 | 2587 |
HECA,ZBTB10,ABCC10,HEXB,TGOLN2,FBXO22,EEF2K,RAD23B,DNM2,ZNRD1,FTSJ3,USP34,CCDC57,ERCC1,NRAS,EHMT1,KIF15,WDHD1,MIER2,DIDO1,MCM2,RAB22A,SMAD2,MID1IP1,RPS27A,MYO18A,OGT,MPV17,COX5A,SMAD1,ZNF75A,ANXA11,SLC25A33,SEC61G,GGA1,MUM1,CCZ1,TRIO,CUTA,RAB23,HAUS4,EIF2AK4,APH1B,CDC73,MYL6B,ATG4A,PDXP,SMC3,GEMIN4,MVP,NUP85,PPP6R1,PABPC1,NSUN4,PPA1,IFRD1,AGGF1,FOXK1,RBM42,GTPBP4,MAP7D1,MRPL16,ELK1,EIF4H,RDH11,MAGED2,KPNA1,ETS2,TYW5,WIPI2,RUFY3,PDLIM5,EXOC3,RHOG,VTI1A,INO80E,SLC35B2,RCOR3,LCLAT1,CPNE3,RBM23,ZNF420,AHCTF1,TBC1D22A,TBC1D14,GMEB1,NSFL1C,GPD1L,ZC3H3,ARL5A,PDCL3,SNX8,EID1,IDH3A,POLR2D,HTATIP2,MEF2D,TMEM147,GSTCD,TANC1,MAT2A,VPS26B,NSMCE2,CORO1C,CAMKMT,PPP5C,PITRM1,TUBB,COMMD10,ZNF445,SRSF6,HABP4,CCM2,FLOT1,BTN3A1,ATG2B,ABHD14B,PPP1R3B,ZBTB45,HUWE1,ZNF260,NAA50,ANXA5,LTN1,UBE3B,NAP1L4,ZNF710,ST8SIA2,SPTAN1,STAU1,TCTEX1D2,DDX24,TACC1,MRS2,LDHA,HEBP2,LLPH,RAB3IP,TTC33,PICALM,SH3BP5,SLC19A1,ACOX1,FAM3C,AEN,PARP10,YWHAH,THAP5,GPATCH4,FAM129A,TRIM11,YTHDC2,SNX15,RBM8A,ENSA,NENF,SND1,RUFY1,TRIM65,ZER1,PRNP,KRR1,RAB8A,NUP210,NT5DC1,NOC2L,EIF5,TACC3,VPS13B,PTPN18,MIOS,MBLAC2,SNRPB,CDC6,UTP3,PBRM1,ODC1,USP21,TRAM2,FBXO28,BCL7C,ARRDC1,ADAM9,DVL1,NUMB,ZNF564,FUBP1,C1orf74,PARP12,ZCCHC9,CENPF,LAMTOR3,CHCHD2,NCKAP1,LYRM2,RSAD1,TNS3,SUB1,RINL,SSBP3,KIF13B,MBD2,XPA,AHCY,RBM3,LRSAM1,HDHD2,NTPCR,NSDHL,AMD1,CAMSAP1,ZNF761,METTL22,ICAM2,STYXL1,APPL1,BBS12,RXRB,SDHB,PCM1,GALNT2,TMEM168,NLRC5,RUVBL2,BTBD10,MYO9A,CCNB2,USP7,GLT8D1,RPLP2,SUCLG1,ARID2,TMX4,SLC2A1,ATP6V1B2,PCBP1,LYN,BCAP31,VAV1,TMEM69,MRPL50,PSMA6,ZNF473,BRPF3,TARDBP,BCAP29,CTDSP2,PRPF19,PPIF,KDM3B,MND1,CLCN3,BIRC3,RAB7A,PPIE,CHMP2B,VDAC1,EIF3H,GLOD4,IDE,DHX16,UHRF2,XRCC3,CHMP4B,PARD3,BCL2L12,C19orf53,MCM10,KLHL21,PDAP1,TMX3,CDCA8,ARF1,SLC12A9,TUBGCP2,DNAJB9,HOMER1,POLR1B,RNF5,RBM15B,PPAN,RHOA,RPRD1A,BTAF1,TOP3A,ARHGEF12,PCGF1,DDX23,RAB18,CACNB1,TRIM26,PDCD6,ATP6V1D,L3MBTL3,FAM110A,NEIL3,CTBS,BBX,IMPDH1,TAF12,NR2F2,PGAM1,HIPK3,IFI16,TXN,NUP188,H2AFZ,PRKCSH,USP39,UBE2I,PARK7,SLC25A37,ZNF428,RAB4A,TRA2B,SUCLG2,TAF5L,SMARCE1,CDC5L,ZNF524,SGCE,OSBP2,NSUN2,USP22,CLNS1A,EIF3A,ZMYM3,DOT1L,IWS1,ANKRD10,WAS,TPP2,C1orf109,ZMAT3,B4GALT2,PRPF38B,RECQL,C9orf78,EWSR1,GADD45G,RRM1,ACAP1,B4GALT1,CYCS,FAM136A,SUPT7L,TMEM165,CNOT3,WDR48,SPAG5,RTKN,CEP104,EXOSC7,KLHL5,LRRC8D,PPP4R1,MSH2,PIGG,FBXL7,OSTF1,MRPL40,SYTL3,FAM171A1,APOL1,EIF5A,GCC2,PRIM2,ELL2,RDH10,MFNG,RPS24,GORASP2,CAPZA2,ADRB2,CCT8,MTR,PHF6,PFDN5,SLCO4A1,TTC13,GOLGA2,RBMX,PIAS2,APPL2,SAMD8,NUDT3,CDKN2A,ZNF511,ATXN3,RAF1,KIAA0232,C2orf49,CD320,EPM2A,CCNA2,MTMR4,BRI3,TP53BP2,AQR,RBM12B,ILKAP,CDK12,SAP30,BRD4,DRAP1,NARF,LRRC8A,ELP4,ABHD11,PKMYT1,ASB13,SERP1,TRIM28,SUPT16H,EIF3K,CHMP4A,CBWD1,ATF6,XRCC4,ADAM23,PRPF4B,NDUFS1,DEPDC1,MECP2,SECISBP2,HMG20A,WWP2,JAKMIP1,SLC25A36,DNAJC8,AXIN2,CITED2,JMJD4,ANKRD37,KAT2A,TMEM126B,RABIF,ADSL,PACS1,BMS1,KCNQ1,ARSK,MACF1,KIF11,COMMD4,KLF6,FADD,SH3GLB1,MYO1F,CBX3,TMEM127,PPP1R11,DUSP11,DDX5,WDR62,TAF6,ESPL1,PURA,DDB1,DEF6,IPO4,UBL3,PIGM,NAT9,LYRM4,GPR132,UBE2Q1,PTP4A3,BRIX1,MRPL19,ZNF696,SF3B2,PCYOX1L,CDC42,GOT2,JAZF1,HADHB,RPF2,SLC35C2,CNNM3,CARM1,SRPK2,WDR41,LARS,ZCCHC10,CCDC138,LRBA,SUMF2,KMT2C,OGFR,PRPSAP1,ASF1B,RPL37,MAN2A2,EIF4ENIF1,NIP7,MIA2,ATP6V0E1,PPP1R2,RGS2,LYAR,FAM89B,POLR2I,TRAFD1,SUGP2,GBA,EIF2A,SYVN1,DAPK3,ARHGAP15,MASTL,UAP1,NFIL3,FN3KRP,YWHAZ,CTSA,TMEM14A,TOB1,TSEN15,ADNP2,TCF12,PRKAB1,MDH2,SMARCA4,ORC1,RRN3,UBXN2A,IARS,CD3EAP,KIF14,EXOSC1,CS,CLTB,DNAL4,CSTF1,POU2AF1,UBQLN4,NXT1,HPDL,PGGT1B,SELPLG,SMU1,ATXN1,GLO1,OGDH,BICD2,CADM1,EDEM2,HERPUD2,TOLLIP,FANCE,MBD3,PDHX,RPS9,ALKBH6,SURF4,DUS3L,ARNTL,ANP32E,FKBP5,TMEM101,CCDC125,ABCA1,PDCD2L,GCLM,RAE1,NUP54,CHIC2,PAWR,MXD4,DCUN1D4,PIP4K2A,XPR1,KIF5B,KLHL20,SEC24C,RRBP1,ARHGEF2,LDLRAD3,STAT3,MYO5A,NIPAL3,AMPD2,TXNL1,PHF20L1,DCAF6,FAM49B,TMEM39A,ATP2C1,RFFL,COG1,RCOR1,PRMT2,TFEB,LEMD2,UPF1,ELMO1,ZC3H7B,ZMIZ1,TERF1,HRAS,CCDC93,FGFR1OP,TMED7,PIGQ,AGPAT1,CNTROB,PPP1R16B,MIS12,GSDMB,TTC9C,PDS5B,NUP153,SENP1,PGAP2,TMEM115,DCUN1D5,PLEKHF2,BRMS1,PWWP2B,TRIM47,WDR11,AXIN1,SMG9,TRIM52,LONP2,NDUFV2,PHF23,CERK,SLC4A2,EZH1,ITGB5,LMNA,MCTS1,DDX56,EIF2S2,SLC38A5,FOXN2,CARS2,PRRC2A,C16orf72,RB1CC1,ZMYND11,PGS1,MYBL2,UHRF1BP1,SRSF5,MPG,MATR3,CYB5A,NCDN,POLR2J,SETD3,CNOT6,NDE1,EGLN1,ZNF207,ANKRD27,ABCA3,SARNP,IVNS1ABP,RMI2,MON1B,TMEM97,NIT2,NUF2,ZNF267,TCF19,TMEM161B,KTN1,APP,PRKD3,CLUAP1,ATP2A2,UTP18,GRSF1,DUT,ANAPC7,RNF19A,FAM76B,CLN6,TMEM9,GCC1,RNF169,ADCY7,ATP6V1G1,ENPP4,RNPS1,CDCA2,FKBP3,DDX17,CHCHD3,PEX5,CDC16,HIPK2,MBOAT1,TICAM1,PDXK,ZBTB11,ANXA6,TMBIM4,GMCL1,UBE4A,IL21R,ETS1,WRB,ZNF92,CAPN2,ADD3,SUV39H2,TTLL12,TPCN1,TMX1,LYPLA2,LDHB,PPP3CA,NUDT8,POLK,JTB,EMP3,MTMR12,ZP3,PDE3B,KIF18A,CCDC6,WNT5B,MAPK6,C4orf46,LY75,SLC25A19,RGL1,PSAP,WDR76,IGBP1,FAF1,COX15,AGRN,THOC1,GNPDA1,GPBP1L1,PPP1R15B,CSNK2A1,EBNA1BP2,GIT2,BIRC2,ATPAF1,DLG5,ABL2,XRCC2,ZFYVE27,MCMBP,PTPRK,CDC37,SP3,EXOSC6,HARS,GMFB,ESYT1,ANLN,RAB5B,RHEB,DPYSL3,TBC1D17,TIMM13,CDCA4,TONSL,NRM,NAGLU,ACTB,ZNF45,TMUB1,CTCF,ASAH1,DOCK11,CRLF3,ASXL2,LRRC14,NUS1,SLC27A4,AFF1,MDFIC,MAML1,CYTH1,NQO2,UTP15,EIF2AK1,EIF4G2,ZDHHC3,MOSPD3,CDC27,SNAP23,TBPL1,PRMT7,KCTD7,NDUFA5,CYLD,UGP2,DYNLL1,COPE,HCFC1R1,ZADH2,GGPS1,RPAIN,RAD23A,ATP6V0B,PDK2,STRBP,DUS4L,MRPL34,PDCD2,SAP30L,SLC39A9,CLPTM1,RPL29,RPL35,BTG2,DNAJC9,MTMR6,FRAT2,NFATC2,KDM1B,ARL5B,USP36,MRPL2,ATP1A1,CLK3,PSMD3,MAFK,CEP55,NDUFA11,DNAJC17,ZNF436,NCOA1,SLC25A39,ZC3HC1,ZNF146,ATXN7L2,CDC40,GOLIM4,SMAP1,RRP15,DAP,GNE,SMC6,ARFIP2,NKRF,CHAC2,BZW2,WRNIP1,SS18L1,CENPM,PTGES3,CAMK2G,MLEC,ZNF202,PPWD1,FAM50B,RHOT2,NEU1,TPD52L2,GOLGA7,TWSG1,PGRMC1,GLG1,FAM126A,RPS6KC1,UBE2C,PPCS,NDUFB6,TMEM41B,ZDHHC8,PLXNA1,CCNB1,SLC20A1,COMMD6,ABHD14A,POLR3K,C14orf119,ASAP2,SNUPN,TFG,PLCL2,SEH1L,ATG9A,PBK,MKI67,DDX20,AMDHD2,GALNT7,SLC17A5,CCNF,FOXRED1,PTER,WDR4,DHTKD1,TRAF5,HDAC2,HSPH1,LIME1,MAPRE1,CHTF18,KIF23,SLC35B1,NOTCH2,PMF1,JMY,FKBP1A,SLC31A1,SNX18,ATIC,ATP6V0A2,PIKFYVE,RNF135,LPCAT1,EEF1D,TMED2,FTL,PHF10,DDX28,ZNF84,SIGMAR1,PIP4K2C,RIT1,PLEC,KDM3A,SF3A2,FAS,EPRS,ZNF777,TMEM54,QARS,PPP3R1,TCOF1,CABLES1,NRBP1,DNMT3A,RWDD1,CKLF,TRIP10,SF3B1,CAST,SUZ12,RPS6KA1,RAC1,GPR89A,OLA1,SNN,GNB2,FLAD1,APLP2,KDM2A,TNPO2,CDKN1B,TALDO1,GPX4,ATP13A1,MAPRE2,RFC3,ERF,CUL3,SLBP,KIAA1586,H2AFV,GAR1,PSMB9,POLG2,DHX57,NSA2,HSPA4,MRPL55,JAK1,TBL3,SEL1L,H2AFX,KLHDC4,B4GALT3,PDCD11,POLQ,POU3F2,OTUD5,NCOR2,ANKRD13D,PKP4,SCAMP3,CDCA3,SLC25A12,BLM,TMCC3,GTF2F1,CRAT,AHSA1,PRC1,UPF2,COPS7B,CNOT6L,UBE2M,IFT46,TMEM160,TSHZ1,ZFP64,DENND4C,DENND1B,WDR18,RPL8,ILF3,LRRC1,RHOT1,MARK2,TSR2,ECH1,PRDX1,PLD3,NUCB1,GNA12,FBXO21,C1orf131,PRDX3,PFDN4,TFDP1,STX18,KHSRP,ASNA1,CPEB2,SSSCA1,VPS29,BYSL,S100PBP,MIB2,IER2,PTMS,NOP2,UBN1,DCAF15,NF1,ALKBH5,MOGS,TAF6L,BECN1,MAPK14,SNAPC4,RNF103,BCAT2,MBD4,METTL14,ZNHIT6,IMPAD1,RCSD1,PHTF1,SRI,NFU1,OGG1,TRIM14,COPS8,FYTTD1,TRIM8,RRM2,SOX4,ABHD5,UBTF,CXXC4,PAF1,UEVLD,SPATA2,PQBP1,IARS2,ATXN2L,GALNT10,STARD3NL,RPS15,PIGN,AGTRAP,CIB1,XPO7,SRRT,ZNF449,CAPZA1,GLTP,BCL2,KIFAP3,N4BP2,HP1BP3,VOPP1,THNSL1,ISG15,CAND1,GNAS,TSC1,RBM25,CDCA5,ZFP90,NANP,RBBP4,ZBTB24,SMARCD1,MBD1,WASF2,MMACHC,TOMM20,IFI27L1,GNPNAT1,CHD1,MEAF6,C2orf68,CCDC50,AKAP8,PARL,RPN2,CHTOP,F2R,FAM3A,SCYL3,TMEM14C,ABI1,HTRA2,MOSPD1,RLIM,FAM172A,ZNF500,PSMB7,NLN,WIPF1,BOLA1,BUD13,NDUFB1,BTBD1,TAB2,CHCHD1,TULP3,WDR59,CANT1,SCARB1,GAS2,USP11,SMURF1,TSPAN5,PPP2R2D,CDS2,MAGEH1,MRPL42,EYA1,CDK2AP2,MRPS26,LETMD1,KLF13,RGS1,HDDC2,MAN1A1,FBXO5,GART,TANK,PELO,BRD7,MRPL11,SAMD4B,ZDHHC18,POLR3GL,WDR81,MEN1,ZNF407,MFN2,COX8A,ZRANB2,MBD6,SRSF3,IDH3B,TATDN1,ATP6V1C1,TSC2,LACTB2,CMTM6,RBM4,ZNF275,ANKRD39,RPL23A,CDKN2C,USF1,MECR,AP1M1,UPRT,CRY2,ECD,RNF26,TIPARP,LRRC59,ANKRD9,RHBDD2,MGAT5,BAK1,ZNF559,RHOBTB3,GABPA,WBP1,NUTF2,ARF4,GINS4,KRIT1,BOLA3,AHNAK,RAD18,PDRG1,RNASEL,CHPF2,OAZ1,PDCD4,SMNDC1,NXT2,HIVEP3,KIAA0100,CLSPN,RHOC,DHX9,PDCD7,PSMD9,HAUS2,COPB2,TFAP4,CD59,RNFT1,RIMS3,MEGF8,FBXO7,EFTUD2,CPSF4,MRPL21,PHKG2,LUC7L2,SRSF11,MTA2,TYW1,USP10,ITM2A,SSR2,BCLAF1,MTX1,SFXN5,FNTA,PDLIM1,ZNF830,MRPL3,ALS2,TRIM41,KARS,NQO1,POC1A,ANK3,PTTG1,TPX2,TBC1D13,DAZAP2,STMN1,C19orf48,REPS1,CBWD5,ABHD16A,FBXL6,SH3BP1,MTA1,UBA5,CLCN6,RPRD1B,CGGBP1,CPNE1,SEC61B,POLR2L,FAM118B,GOPC,E2F3,CIRBP,RPL38,CRNKL1,PFKFB3,GORAB,RAB1A,GIGYF1,TMEM184C,PPP2CA,KIF2A,CCDC14,LSM6,RNF38,SNRPG,DMWD,USP13,ZFP91,IP6K2,WDR5,SLC25A43,IFT27,PMVK,NEIL2,RRP36,SRXN1,RPA2,PSMD2,CLIC4,PDCD10,CBWD2,COQ4,ITGB8,ARF5,ARHGEF1,FBXL19,GTF2H2,TTPAL,UTP20,MAGT1,GPS2,DBI,SSNA1,MRFAP1L1,CD81,WDR13,FANCI,PAPOLA,CREM,FANCL,GLIS2,IL6ST,POP7,SLC44A1,MTPN,ASB6,PLK1,RPP25,SEPT9,CELSR2,RBX1,APH1A,RAD51AP1,CKAP2L,UBE2V1,EAF2,IL12RB1,KRTCAP2,LUC7L,LSG1,NECAP2,C1orf122,TRIM4,AGPAT2,CHD3,ZNF367,E2F4,PRPF4,KPNA2,BEND6,CLN3,DNAJC30,NGLY1,POT1,MYL12B,RMND5A,DNAJB2,FAM53C,NKD2,SDC2,KLC1,CDK13,ADCK5,COX4I1,DNAJB1,RAB6A,ARID1B,C1GALT1,MLX,CCP110,ZNF746,ARL6IP1,CTR9,NIPSNAP1,ABHD2,DCAF8,ACSL3,LDB1,MAP4K3,ARMC8,NMT2,IRF5,RPL36,HAUS8,MBIP,ORMDL2,COX7A2L,ZDHHC7,SIL1,FAM122A,UNC13C,BCCIP,SART1,TRAF7,NDUFAF2,TOR1AIP1,ZNF416,LAGE3,ZFYVE21,TM9SF3,RRAGC,ZNF121,OIP5,NRF1,WDR44,PPME1,PIN1,EFCAB11,RPAP1,CABLES2,LMAN1,AHCYL1,TOP1MT,STRAP,SPSB3,ZNF583,SNX25,ARHGAP17,POLR2G,PPT1,NUP155,DCLRE1C,MRPS14,RHBDF2,SUGP1,RBL1,FASTK,STK38,AP1S1,H3F3A,CHID1,SMAD4,RAD51D,SLC30A9,CMAS,NADSYN1,HMGN3,NCAPG,SCYL2,FZD6,HERC3,GTPBP3,CTSS,ORC3,RNLS,YTHDC1,ACP2,HMGN5,CSRP1,METTL5,ABCF2,TUFM,RANGAP1,PNPLA8,HAGH,API5,ZFR,SEC23IP,E2F1,TMEM219,USP20,RBPJ,PDCD6IP,MAX,LUZP1,ADAM10,CXXC1,TSC22D3,AP3M2,CUL1,GYG1,NANS,OAT,MYEF2,ANKRD26,PA2G4,NOL11,FIZ1,ZNF200,SLC26A2,SRP72,KLF10,LACTB,CBFB,RFC2,RAB2B,MAP3K4,HHEX,LUC7L3,RPS14,MAP4,MRPL27,BTF3,PTPDC1,NMD3,CCDC59,PTOV1,COX5B,DNAJC5,SCOC,DHPS,POLR2K,ANKH,PRKAA1,C16orf87,VAV2,GSPT2,DLGAP4,PXMP2,PSEN1,ZNF79,PDXDC1,VPS25,NDUFS7,YY1AP1,C12orf10,FAM192A,RPN1,LHX8,ARPC5,ZNRF2,TPST1,DAPK1,PIK3IP1,CYC1,SOCS5,FDFT1,PIGT,EMB,ZNF574,C1orf35,EXOSC9,ARID1A,PTTG1IP,C9orf40,FXR1,GOSR1,MAP2K2,TWISTNB,AKAP1,XRCC5,HMGN2,PI4K2A,CAT,SEC31A,DERL1,HSPBP1,MTHFD2,CEBPG,ARAP1,USP32,FAM83D,CABIN1,SMPD4,GPI,CYTIP,TP53RK,REPS2,RAB11B,UROD,SLC39A13,POMP,BCL2L1,DECR1,RALB,SIAH1,ADCY9,LPIN2,MRPS27,SOCS6,TTC3,RNASEH2A,CFL1,CDC123,OAF,VDAC2,EDF1,EML4,ERC1,ANKZF1,RAD51C,ZNF282,DSN1,DDOST,HINT1,DGCR8,SAFB,HAGHL,RWDD4,FTSJ1,LMBR1,NCLN,EYA2,DYNC1LI2,MANBA,SLC41A1,B4GALT5,FAM76A,TKT,CBLL1,ARGLU1,LANCL1,POFUT1,FAM8A1,HEATR5B,HLA-A,EBP,RFWD3,NDUFA2,FJX1,FUT8,BTF3L4,PTPN11,MRPL54,FEM1B,RPL19,CNN2,NDUFA3,MTX2,MSH6,PDLIM2,LONRF3,RFXANK,FBXO9,GUF1,RPL32,ZHX1,NDUFS5,WDR91,GPR89B,HIGD2A,ZBED3,RORB,POLA2,ZNF76,COPA,UQCR10,PHRF1,ABCB10,COMMD5,MAP1LC3B,DST,RAB35,SIVA1,GPATCH1,TCEA1,DRAM2,DEAF1,SNRNP200,LAP3,NCK1,VHL,SREK1,ARHGDIB,PITPNB,HSPB11,BRWD1,PPM1G,SH3GLB2,CRCP,BAZ1B,CAB39,ACBD4,STK11,CLU,CHEK2,ZSWIM3,TSTD2,CHPT1,MRPL13,DCAF5,CAPN1,UBE2D3,NSMCE4A,PPP1R12A,ZCCHC8,GORASP1,NACA,UBXN1,RPL15,PCSK7,EPN1,THRAP3,QSOX2,TTF1,PRPF18,NUP205,CHKA,DTL,MED10,ZRANB1,MCPH1,SLC12A2,ATP6V0D1,CSNK1G3,CREG1,NUDT4,RPL6,VKORC1,SLTM,EVC2,KLHL15,SIAH2,SLC16A1,EHD4,SNRNP70,C11orf1,APOL2,SNX27,CHMP2A,CORO7,UCK2,PMS2,UCK1,CLCC1,EXT2,MXD1,USP5,SAP130,NVL,PPP6C,CYB5R1,ZNF770,EBAG9,RNF25,PCGF6,METTL2A,PON2,STAT6,HPS5,MAPK1,BRD9,TMEM33,NAT14,DNAJC2,TRIP12,SHPRH,SCYL1,VPS45,MYO9B,GFM2,SPPL2A,FASTKD3,FGFR3,PPIG,ZDHHC13,TMEM99,H2AFY,NDUFS8,ERI3,FBL,SLC35A1,FRMD8,B3GALT6,TGFB1,ELOVL5,HEMK1,TIMMDC1,HELB,PSPC1,MIER1,SCFD2,NDRG3,MTMR3,ACAT1,CENPT,PLOD3,RAB3IL1,ZSWIM6,RAB14,ADD1,KDM4A,MRPS15,XIAP,DHX8,GLUD1,ANKRD23,PABPC4,CDK5,CALM2,PSMD1,NEK6,NSRP1,RABGAP1L,SRSF4,KCNAB2,PCBP2,MLST8,PLK3,ZNF672,MRPL43,HSDL1,TOPORS,MCL1,PPFIA3,SMC2,ICMT,STOML2,LIMK1,PRDX5,ATE1,MLYCD,ST3GAL2,ATP6V0C,FBXL3,TFDP2,E2F2,PFKP,AAAS,DDX42,SSRP1,MRPL9,MRPS2,STRN4,TOP2B,TMED3,DDRGK1,RAVER2,GNS,INTS7,INPP5A,MCM5,PHF14,ZNF326,NAGPA,TIMM8B,ETV3,DHX29,TEX10,MAN1B1,RPS10,CBFA2T2,ABCF1,RHOB,DTWD1,PTPRF,SCARB2,OSBPL11,CCDC86,DUSP3,SLAIN1,MDH1,HEXA,RNF139,SNX14,ZNF296,TRERF1,UBR2,CHD1L,ACTR3,WDTC1,MYH9,CREBL2,NIPA2,PRKACA,SAFB2,ANKIB1,STAM,ARL6IP6,RAB21,SP100,ZKSCAN1,DDA1,NUP107,ANKRD13C,MAVS,TMEM136,ATF2,RBM15,DCTN1,SHOC2,PSRC1,MAP4K4,WBP2,ATP6V0A1,DNAJA1,NDUFA7,TAZ,TAF2,SEC61A1,RPLP1,WDR7,CBLN2,RBMS1,FUS,GEN1,LRP8,COIL,LRCH1,GALK1,ZNF786,RPS2,SESTD1,TRAK1,JMJD6,SIKE1,AKT1S1,FBXO3,ERH,PPP1R8,PRDM4,GTSE1,GEMIN6,DCP1A,SGCB,S100A6,IMPA2,NUDC,PDPK1,TK1,GUK1,TNFAIP3,GALC,ZNF512,KIAA0930,MRPS10,DDX39A,RPA1,ZNF180,KEAP1,POLE,TATDN2,PITX1,CAPN7,LRPPRC,PML,HMGB2,USF2,ANAPC4,SRM,DDX47,MCCC1,CDC42SE2,S1PR2,CDIPT,SEC16A,SSR1,LIN9,PCNA,ZNF639,ETV6,PIK3R2,TXLNA,PPCDC,FAM86C1,MYBL1,CCAR1,MRPL32,ABCC5,BAZ2A,PBXIP1,TLK1,MRPL12,LNX2,LRP5,BRCA1,PRKRA,STX16,EPB41,OPTN,SOCS4,QRSL1,GLCCI1,NUDT11,NAA60,GEMIN7,SEPHS2,LZTR1,RACGAP1,PPP3CB,B4GALT4,RLF,RAPGEF6,SNRNP25,RB1,VASP,VMP1,PPIL2,MEA1,TIMELESS,AHDC1,ALDH18A1,TMEM8A,PREB,ABCC1,TRAPPC9,AACS,MEMO1,KRAS,RTF1,UBE4B,NFATC2IP,LY6E,ARPC1A,ZNF174,PSMC4,GOLGA4,PALB2,SYNCRIP,PRPS2,NIPA1,TIGD2,RNF114,FOXM1,MRPL39,XAB2,SUMO2,DUSP22,COMMD8,RPL11,CSDE1,MDM2,CORO1A,MINPP1,METTL9,POC5,DVL2,GM2A,PSMA8,COQ10B,CPOX,TIGD5,SLC26A6,CYP20A1,PRPF3,TXNL4A,RPSA,SRSF1,DNAJC10,ZNF700,SCAP,PLEKHG4B,TIMM17A,FAU,LTA4H,AP2S1,USP53,INTS2,CTDP1,MIF4GD,CDT1,ARID5A,SUMF1,GGA2,CSNK1A1,AP3S1,RMI1,TFRC,PTPN2,IRF4,GSTK1,NDUFV1,SLC1A4,CWC27,SLC35B4,DDX31,ABCD1,CNTN5,SNX2,ZMYM5,CCDC34,CHCHD6,BSDC1,CDKN2AIPNL,FBXO41,KPNA4,BIRC5,TFE3,SNAP29,CDCA7L,PKD2,ACADM,CHMP7,SAT2,GCSH,ZNF496,TMEM109,TAP1,NHLRC3,IKBIP,EIF1B,ELMOD2,KIFC1,DBNDD1,RNASEK,CDC25B,PRADC1,DNMT1,NOL12,ORAI2,AKT2,GNG7,AURKB,MCFD2,SLC25A5,ZFAND5,STT3A,TMED10,EIF2D,ITGB1,PTPN7,UQCRH,RRS1,ARRB2,RTN3,DDX58,WSB2,PPIB,MUT,GMFG,HLA-E,NDUFA4,MAN2B1,METTL3,CFLAR,NDUFS4,RNF121,MEX3C,KLF16,HDAC7,DAD1,BDH1,GNAI2,ANKHD1,MORC3,TERF2,KCTD20,DCTD,TOMM40,ADSS,SERTAD2,SERF2,ZFP92,NSF,DCK,ERGIC3,ACLY,LPCAT4,VCPIP1,PPP6R2,PPP6R3,MAP3K5,YY1,CDK2,RNF14,ZC3HAV1,ZBTB37,URB2,MAGED1,KLHL18,ADPGK,SLC25A44,AP1B1,SDHA,PAIP2,PHC2,CRKL,TERF2IP,MOAP1,CYHR1,ZNF75D,SHC1,UCHL5,NAA35,TMBIM1,CDKN2AIP,CCT2,MKLN1,HMGN4,GALK2,CDC23,SHCBP1,AP4E1,PRDM11,VEZF1,PPP2R5A,ACYP1,STAT1,PPA2,TRIM32,RHEBL1,C1orf112,TCF3,MRI1,BRAP,AGPAT3,MYNN,SDF2L1,SPR,RAB11A,REEP5,FOXO3,MAD2L2,CCDC28A,PIP5K1C,RBM17,MAT2B,PTEN,CENPJ,TAGLN2,OSTC,CREB1,NCOA2,PACS2,SMC4,RNASEH2C,NEK7,NET1,PARP4,TBRG4,ANAPC2,RPL27A,YIF1A,SGSH,HGS,TTLL4,SLC38A7,MFAP1,CCDC69,BRWD3,ESYT2,SKA3,NPHP4,UBE2E2,PLXNC1,ST13,DNAJC24,SLC29A1,KIF2C,AGFG1,SIRT2,USP48,UBQLN2,SNRPD3,FKBP2,CUTC,EDC3,UBLCP1,ZNF804A,RAP1A,THADA,EIF4A3,AP3S2,ATG3,DPYSL2,PPP1R12C,AKR1B1,NDUFB9,JOSD1,RP2,TTC4,TECR,ARID4A,FGFR1OP2,TIMM50,TDP1,DPM1,FOPNL,SLC16A7,WDR82,SLC25A22,STK17B,DHX15,CHAF1A,GEMIN5,COPS6,RPS26,PSMC1,SLC12A7,TBC1D12,TM9SF4,ZNF768,MED13L,TIA1,EPHX2,PITHD1,RHBDD1,NFATC3,BANF1,ZNF335,BUD31,YBX1,KNTC1,ACAD8,UBE3C,ZNF189,ALDH9A1,KDELR1,TSTA3,CIC,OXR1,PSMA1,SEPT7,NAP1L1,ODF2,EXOC4,KIAA1328,NUP62,PITPNA,NAA20,PTDSS1,MZT2B,PDSS2,C7orf26,TMEM106C,IMMT,ASH1L,CHERP,WDYHV1,PLAGL2,CHKB,IRF3,TWF2,PAIP1,ANKRD28,FARSA,SAR1A,SCAMP4,APOOL,PDIA6,ACSL5,AZI2,GFER,RAD54B,TMEM41A,DAP3,ZNF317,GADD45B,AKNA,REEP4,CBX4,MIF,KIF3B,GOLPH3L,SH2D3A,CASP6,TOR3A,SRGN,DBF4,SAC3D1,CTNNBL1,CLDND1,TTC17,SLC25A1,GINS1,PAQR6,CSNK1G2,TELO2,ADAM17,HMGN1,NASP,ASPM,SYMPK,TARS,SNRPA,MAPK3,HSPA1B,HLA-B,ATAD2,PLAA,ZNF330,OSBPL8,KBTBD7,PREPL |
| 4.706e-10 | -21.48 | RNA transport | biological process | GO:0050658 | 186 | 62 | 17256 | 2622 |
RPS15,NDC1,TOMM20,NUP188,CDC40,SARNP,THOC1,SRSF6,RAE1,RBM8A,DHX9,ALKBH5,FLOT1,NUP54,AGFG1,XPO7,NUP205,HNRNPA2B1,AHCTF1,NUP210,SNUPN,EIF4A3,SRSF4,NUP107,UPF2,NUP153,GLE1,CHTOP,MVP,CPSF4,ZC3H3,NUP85,SEH1L,SRSF11,EIF5A,FYTTD1,NXT1,POLR2D,RNPS1,SLBP,NUP155,BICD2,NUTF2,SRSF5,DDX39A,SYMPK,NPIPA1,RPSA,SRSF1,IWS1,HHEX,TSC1,UPF1,LRPPRC,KHSRP,NUP62,SRSF3,RRS1,NMD3,NUP58,AAAS,NXT2 |
| 4.706e-10 | -21.48 | nucleic acid transport | biological process | GO:0050657 | 186 | 62 | 17256 | 2622 |
RPS15,NDC1,TOMM20,NUP188,CDC40,SARNP,THOC1,SRSF6,RAE1,RBM8A,DHX9,ALKBH5,FLOT1,NUP54,AGFG1,XPO7,NUP205,HNRNPA2B1,AHCTF1,NUP210,SNUPN,EIF4A3,SRSF4,NUP107,UPF2,NUP153,GLE1,CHTOP,MVP,CPSF4,ZC3H3,NUP85,SEH1L,SRSF11,EIF5A,FYTTD1,NXT1,POLR2D,RNPS1,SLBP,NUP155,BICD2,NUTF2,SRSF5,DDX39A,SYMPK,NPIPA1,RPSA,SRSF1,IWS1,HHEX,TSC1,UPF1,LRPPRC,KHSRP,NUP62,SRSF3,RRS1,NMD3,NUP58,AAAS,NXT2 |
| 4.720e-10 | -21.47 | GO_MICROTUBULE_ORGANIZING_CENTER | MSigDB lists | GO_MICROTUBULE_ORGANIZING_CENTER | 577 | 143 | 17377 | 2626 |
FGFR1OP,NPHP4,PDCD6IP,SIRT2,CNTROB,CCNB1,KIFC1,CALM2,ANKRD26,RAB8A,PCNA,NEK6,CDC42,XRCC2,DNM2,SUCLG2,FNIP2,RP2,CDC25B,PLK3,PLK1,RPP25,AATF,FOPNL,KIF15,EZR,CKAP2L,TOPORS,AURKB,BRCA1,CCNF,SEPT1,HSPB11,RAD18,CHD3,PQBP1,ROCK1,VPS4A,SASS6,TRAF5,AAAS,MAPRE1,TMUB1,PPP1R12A,CENPF,CIB1,DHX9,KIF23,HAUS4,PSEN1,HAUS2,SPAG5,DTL,CEP104,CCP110,KIFAP3,FBXL7,GNAI2,MCPH1,ATP6V0D1,ELL2,PSMA1,CCT8,HAUS8,MASTL,PCM1,CDC27,ODF2,SLC16A1,MDH1,NDE1,CDK2,CCNB2,MZT2B,ALS2,CYLD,RAB11B,POC1A,DYNLL1,OLA1,NIT2,BCL2L1,PRKACA,MEAF6,CLUAP1,NUP107,CEP63,RNF19A,RPRD1B,POC5,DCTN1,TUBGCP5,KIF2A,CDC16,CCDC14,CEP55,XRCC4,MAPK1,GEN1,RAD51D,DYNC1LI2,CSNK1D,KIF3B,CTDP1,MZT1,KLHL21,SCYL1,DCTN2,FLOT1,NCAPG,IFT27,CSNK1A1,TUBGCP2,RAB11A,SAC3D1,KIF5B,STARD9,CLIC4,MZT2A,SLC1A4,CENPJ,AXIN2,IFT46,TACC1,NEK7,JTB,WDR81,RAB3IP,SPPL2B,HSPA1B,YIF1A,ATP6V1D,NEK1,KIF18A,KEAP1,FAM110A,BIRC5,SNAP29,USP20,SSNA1,PKD2,WDR62,ESPL1 |
| 4.814e-10 | -21.45 | GO_NUCLEOBASE_CONTAINING_COMPOUND_TRANSPORT | MSigDB lists | GO_NUCLEOBASE_CONTAINING_COMPOUND_TRANSPORT | 187 | 62 | 17377 | 2626 |
TOMM20,CDC40,SARNP,NUP188,THOC1,RAE1,SRSF6,RBM8A,ALKBH5,NUP54,FLOT1,AGFG1,SLC29A1,SLC35B1,SLC35B2,XPO7,NUP205,SLC25A36,HNRNPA2B1,SNUPN,AHCTF1,NUP210,EIF4A3,SRSF4,SLC35B4,NUP107,UPF2,NUP153,GLE1,CHTOP,SLC35C2,MVP,SLC35A1,ZC3H3,NUP85,SEH1L,SRSF10,FYTTD1,SRSF11,EIF5A,NXT1,RNPS1,POLR2D,SLBP,NUP155,SRSF5,BUD13,DDX39A,RPSA,SRSF1,IWS1,TSC1,HHEX,UPF1,LRPPRC,KHSRP,SLC25A19,NUP62,SRSF3,SLC25A33,AAAS,NXT2 |
| 4.845e-10 | -21.45 | GO_PROTEIN_COMPLEX_BIOGENESIS | MSigDB lists | GO_PROTEIN_COMPLEX_BIOGENESIS | 1070 | 235 | 17377 | 2626 |
COX15,MAX,ST13,NDUFB6,UBN1,UQCR10,XIAP,SIRT2,OAT,CCNB1,SEC16A,CUTC,BIRC2,ATPAF1,MIS12,PRNP,KIFC1,DLG5,NAPG,NEK6,DNAAF2,ZNHIT6,AP2B1,NDUFB9,NUP153,TFG,USO1,SEPT9,NCK1,LNX2,PSMG1,RRM2,AURKB,MCFD2,ANLN,MCM2,FOXRED1,ASF1B,CHAF1A,STOML2,DPYSL3,GEMIN5,TRIM4,AHNAK,MID1IP1,SMAD2,WAS,BRD2,TMED10,PSMD8,AXIN1,OGT,CAB39,STK11,CLU,CHEK2,SMAD1,NAA60,SLC25A33,NDUFV2,HJURP,GORASP1,DHPS,PRKAA1,CENPF,KCTD17,RRM1,KIF23,RACGAP1,HAUS4,PSMD9,HAUS2,CDC73,NUP205,NDUFS7,NDUFS4,CD59,TFAP4,FKBP1A,VASP,SSBP3,MBD2,CAPZA1,ATP6V0A2,KIFAP3,KNTC1,ALDH18A1,PPP6R1,TMED2,PREB,HP1BP3,TRAPPC9,TSPYL4,MYBL2,ADRB2,CAPZA2,SEPT7,EIF4H,CCT8,BBS12,HAUS8,CAND1,FAS,DERL1,CAT,SEC31A,TSC1,EPRS,NAP1L1,GOLGA2,NSF,SNAP23,RBMX,NUP62,CABIN1,PPP6R3,EHD4,RBBP4,NDE1,PDSS2,ZNF207,KCTD7,CHMP2A,PRKAB1,NDUFA5,CORO7,CYLD,TOMM20,REPS2,NDUFAF2,RAF1,SLC2A1,RAC1,TPX2,SMARCA4,POMP,ANKRD28,OIP5,DECR1,MDM2,AHCTF1,NUP107,PPP6C,SEPT11,TNPO2,CEP63,LMAN1,DVL2,CCT2,BIRC3,GOPC,TUBGCP5,CUL3,ATP6V0A1,WIPF1,NDUFA7,NDUFB1,RAB1A,TAZ,TRIM28,KIF2A,IDE,CHMP4A,PEX5,HSPA4,NDUFA11,H2AFX,CHMP4B,H3F3A,PPP5C,AP2S1,SMAD4,PARD3,TUBB,CSNK1D,TMEM33,POLQ,MIF,KIF3B,NDUFS1,ANXA6,SHPRH,NUP54,FLOT1,BLM,CSNK1A1,RAB11A,TUBGCP2,FERMT3,FBXO5,STARD9,NDUFV1,NDUFA2,NDUFB4,CENPJ,SEC24C,AXIN2,H2AFY,ANXA5,NDUFS8,NAP1L4,CENPM,TTC17,NDUFA3,CAMK2G,TGFB1,TK1,RHOA,NASP,TNFAIP3,SNX2,TIMMDC1,ASPM,NEK7,TMEM126B,ADSL,MEN1,KIF11,PICALM,SH3GLB1,FADD,MAPK3,KEAP1,SEC23IP,BIRC5,SNAP29,PML,ACAT1,HMGB2,CENPT,NDUFS5,UBE2C,TERF1,HRAS,IPO4 |
| 4.845e-10 | -21.45 | GO_PROTEIN_COMPLEX_ASSEMBLY | MSigDB lists | GO_PROTEIN_COMPLEX_ASSEMBLY | 1070 | 235 | 17377 | 2626 |
COX15,MAX,ST13,NDUFB6,UBN1,UQCR10,XIAP,SIRT2,CCNB1,OAT,SEC16A,CUTC,BIRC2,ATPAF1,MIS12,PRNP,KIFC1,DLG5,NAPG,NEK6,ZNHIT6,DNAAF2,AP2B1,NDUFB9,NUP153,TFG,USO1,SEPT9,NCK1,RRM2,LNX2,PSMG1,AURKB,MCFD2,ANLN,MCM2,FOXRED1,ASF1B,CHAF1A,DPYSL3,STOML2,GEMIN5,TRIM4,WAS,MID1IP1,AHNAK,SMAD2,BRD2,TMED10,PSMD8,AXIN1,OGT,CAB39,STK11,CLU,CHEK2,SMAD1,NAA60,SLC25A33,NDUFV2,HJURP,GORASP1,DHPS,CENPF,PRKAA1,KCTD17,RRM1,KIF23,RACGAP1,HAUS4,PSMD9,HAUS2,CDC73,NUP205,NDUFS7,NDUFS4,FKBP1A,CD59,TFAP4,VASP,SSBP3,MBD2,CAPZA1,ATP6V0A2,KIFAP3,KNTC1,ALDH18A1,PPP6R1,TMED2,HP1BP3,PREB,TRAPPC9,TSPYL4,MYBL2,ADRB2,CAPZA2,SEPT7,EIF4H,CCT8,BBS12,CAND1,FAS,HAUS8,DERL1,CAT,SEC31A,TSC1,EPRS,NAP1L1,GOLGA2,NSF,SNAP23,RBMX,NUP62,CABIN1,RBBP4,PPP6R3,NDE1,EHD4,PDSS2,KCTD7,ZNF207,NDUFA5,PRKAB1,CHMP2A,TOMM20,CYLD,CORO7,REPS2,NDUFAF2,RAF1,RAC1,SLC2A1,TPX2,SMARCA4,POMP,ANKRD28,OIP5,DECR1,MDM2,AHCTF1,PPP6C,NUP107,TNPO2,SEPT11,CEP63,LMAN1,DVL2,CCT2,BIRC3,GOPC,CUL3,TUBGCP5,WIPF1,ATP6V0A1,NDUFA7,NDUFB1,RAB1A,TAZ,TRIM28,KIF2A,HSPA4,PEX5,IDE,CHMP4A,NDUFA11,H2AFX,CHMP4B,PPP5C,H3F3A,AP2S1,SMAD4,CSNK1D,TUBB,PARD3,POLQ,TMEM33,MIF,KIF3B,NDUFS1,ANXA6,SHPRH,FLOT1,NUP54,BLM,CSNK1A1,RAB11A,TUBGCP2,FBXO5,FERMT3,STARD9,NDUFV1,NDUFA2,NDUFB4,CENPJ,SEC24C,AXIN2,ANXA5,H2AFY,NDUFS8,CENPM,NAP1L4,TTC17,NDUFA3,CAMK2G,TGFB1,TK1,RHOA,NASP,TNFAIP3,SNX2,TIMMDC1,ASPM,NEK7,TMEM126B,ADSL,MEN1,KIF11,PICALM,FADD,SH3GLB1,MAPK3,KEAP1,SEC23IP,BIRC5,SNAP29,PML,ACAT1,HMGB2,NDUFS5,CENPT,UBE2C,TERF1,HRAS,IPO4 |
| 4.955e-10 | -21.43 | RPL18A (ribosomal protein L18a) | protein interactions | 6142 | 217 | 72 | 17029 | 2761 |
CYLD,NOP2,RPLP2,URB2,SF3B1,YTHDC2,DHX8,CUL1,EBNA1BP2,BRIX1,RBM4,PABPC4,RPL11,RPL23A,PA2G4,NOC2L,TARDBP,FTSJ3,RPL35,VHL,RPL38,RIOX2,BRCA1,DIDO1,PRKRA,MCM2,RPS9,RPSA,CENPU,NSA2,RPS27A,ZNF689,RPS14,RPLP1,RRS1,PDCD11,RPS26,NIFK,RPS15,RPS2,RPL15,TTF1,LYAR,RPA2,SUB1,DDX56,RPL17,RBM34,DDX31,RPL19,FBL,PABPC1,HNRNPM,LUC7L2,STAU1,DDX24,GTPBP4,ILF3,RPL8,RPL6,RPS10,RPS24,BMS1,KRAS,CAPZA2,RPL27A,CAND1,RPL36,RPA1,RPL32,BBX,ZC3HAV1 |
| 5.025e-10 | -21.41 | HNRNPH1 (heterogeneous nuclear ribonucleoprotein H1) | protein interactions | 3187 | 188 | 65 | 17029 | 2761 |
USP7,CYLD,HNRNPAB,SUMO2,CUL1,IKBIP,RBM4,CPNE3,HNRNPA2B1,SHC1,EIF4A3,PIN1,TARDBP,ATF2,CDC5L,CPNE1,VHL,HNRNPF,CUL3,SREK1,BRCA1,MCM2,DDX17,PPP2CA,AHNAK,HNRNPR,DGCR8,IARS2,KPNA2,FUS,COPS6,ARRB2,SMURF1,C9orf78,UNK,SCOC,PSMD9,LMNA,RPA2,HUWE1,AHSA1,RTCB,TNPO3,HNRNPM,PPP3CA,STAU1,TSTA3,ADRB2,MATR3,CAND1,RPA1,CNOT9,PDCD6,SYNCRIP,HNRNPH3,RBMX,PGRMC1,KHSRP,DDX5,SNRNP70,HNRNPDL,ECPAS,CD81,HIPK3,NUP58 |
| 5.142e-10 | -21.39 | PRPF19 (pre-mRNA processing factor 19) | protein interactions | 27339 | 184 | 64 | 17029 | 2761 |
EXOC3,SART1,CYLD,XAB2,SUZ12,SF3B1,DHX8,CUL1,USP39,EIF4A3,UCHL5,GPATCH1,KHDC4,TARDBP,ECD,AQR,TP53BP2,GCC1,PRPF19,CDC5L,SNRNP200,PPIE,CRNKL1,RNPS1,CUL3,PRPF3,BRCA1,DHX15,SRSF1,PRPF4,KPNA2,DDX42,UBE2D3,CDC40,UBXN1,LMNA,RPA2,RPN1,GSTK1,CTNNBL1,HUWE1,AHSA1,EFTUD2,PTPN11,BUD31,LTN1,HNRNPM,SRSF11,SF3B6,RPS10,RPS24,SRSF5,SF3A2,POLR2A,SNRPA,CAND1,RPA1,KPNA1,RBM25,YJU2,DDX5,ISY1-RAB43,ZNF830,SNRNP70 |
| 5.179e-10 | -21.38 | GSE41176_WT_VS_TAK1_KO_ANTI_IGM_STIM_BCELL_24H_UP | MSigDB lists | GSE41176_WT_VS_TAK1_KO_ANTI_IGM_STIM_BCELL_24H_UP | 196 | 64 | 17377 | 2626 |
KCTD7,NQO1,UBN1,TMEM41B,KIAA0232,OAT,SEC16A,BCAP31,RNF103,MOAP1,IL6ST,JOSD1,ATF2,RYBP,PPIF,ERF,TLK1,EZR,HTATIP2,MEF2D,MCFD2,ZFAND5,ODC1,RAB5B,UBTF,AHNAK,ATP6V0C,FAU,PTOV1,GCLM,CDS2,KLHL21,RHOC,TKT,KLC1,JMJD6,GGA2,DNAJB9,LMNA,NDUFS7,ARF5,RRBP1,FAM89B,CNPY3,ATP6V0D1,KDELR1,SLC25A1,CREG1,ACSL3,CAMSAP1,GORASP2,RIT1,RHOB,NUCB1,KEAP1,SERTAD2,GOLGA2,SETD3,TFE3,YWHAZ,PITPNA,SRSF3,WIPI2,HRAS |
| 5.208e-10 | -21.38 | GSE14000_TRANSLATED_RNA_VS_MRNA_4H_LPS_DC_UP | MSigDB lists | GSE14000_TRANSLATED_RNA_VS_MRNA_4H_LPS_DC_UP | 183 | 61 | 17377 | 2626 |
CCDC93,SART1,GCLM,FAM208B,MPHOSPH8,RRP15,ZCCHC8,RBM8A,MON1B,SMC6,SMARCA4,USP48,OAT,RUFY1,GFM2,MCTS1,MOAP1,PSMD1,DNAJC8,KDM2A,PPIG,ZNF326,PTPN11,UPRT,ATP6V0A2,SMARCE1,NAA35,SCYL3,CCAR1,RNLS,RPAP3,PDPK1,NASP,HMGN5,KAT2A,SNX2,DHX29,NSDHL,ZBED5,GTPBP4,ELP4,LLPH,NFATC2IP,PPWD1,BUD13,CDK11A,PDHX,FKBP3,SUPT16H,C1orf131,UEVLD,NSMCE2,WDR4,DUSP11,GLCCI1,TRAF5,LONP2,ANAPC4,NUMB,ZC3HC1,DDX52 |
| 5.208e-10 | -21.38 | GSE22589_HEALTHY_VS_HIV_AND_SIV_INFECTED_DC_UP | MSigDB lists | GSE22589_HEALTHY_VS_HIV_AND_SIV_INFECTED_DC_UP | 183 | 61 | 17377 | 2626 |
MMACHC,PIGN,C19orf53,MUT,COPA,NDUFAF2,DNAJC24,USP39,LCLAT1,SDHA,PDXDC1,RTKN,RRN3,PSMD1,FBXL6,CCNA2,COQ4,VMP1,INTS7,AP3S2,ATP13A3,SOCS6,ZBTB22,KNTC1,TTC4,GLE1,ALDH18A1,STRAP,PREB,PLK3,PHF10,PRIM2,PSMA8,GALC,IDH3A,PPP1R21,NSUN2,WDR18,SCFD2,MAP7D1,ABHD11,PPWD1,COMMD4,LUC7L,TARS,CLNS1A,PRIM1,EPRS,BRWD1,TTLL4,HNRNPR,DGCR8,RBMX,PPM1G,CDCA5,IARS2,WDR76,TAF6,NGLY1,GCSH,SVIP |
| 5.238e-10 | -21.37 | GO_CENTROSOME | MSigDB lists | GO_CENTROSOME | 456 | 119 | 17377 | 2626 |
FGFR1OP,NPHP4,CYLD,POC1A,DYNLL1,OLA1,NIT2,SIRT2,BCL2L1,CNTROB,CCNB1,PRKACA,MEAF6,CALM2,ANKRD26,CLUAP1,RAB8A,PCNA,XRCC2,NUP107,DNM2,RP2,CDC25B,CEP63,RNF19A,RPRD1B,POC5,DCTN1,PLK3,PLK1,AATF,FOPNL,TUBGCP5,KIF15,CKAP2L,TOPORS,AURKB,CCNF,KIF2A,HSPB11,CDC16,RAD18,CHD3,CCDC14,CEP55,PQBP1,ROCK1,VPS4A,SASS6,GEN1,TRAF5,XRCC4,AAAS,DYNC1LI2,RAD51D,CSNK1D,KIF3B,CTDP1,MAPRE1,MZT1,PPP1R12A,KLHL21,CENPF,DCTN2,FLOT1,CIB1,DHX9,KIF23,HAUS4,CSNK1A1,PSEN1,NCAPG,IFT27,RAB11A,TUBGCP2,HAUS2,SPAG5,DTL,STARD9,CEP104,MZT2A,CLIC4,SLC1A4,CCP110,CENPJ,AXIN2,FBXL7,KIFAP3,GNAI2,ATP6V0D1,IFT46,ELL2,JTB,PSMA1,RAB3IP,WDR81,SPPL2B,CCT8,HSPA1B,HAUS8,MASTL,PCM1,ATP6V1D,NEK1,CDC27,BIRC5,SNAP29,ODF2,SLC16A1,USP20,MDH1,SSNA1,NDE1,WDR62,CDK2,CCNB2,MZT2B,ESPL1,ALS2 |
| 5.242e-10 | -21.37 | SF3A1 (splicing factor 3a subunit 1) | protein interactions | 10291 | 180 | 63 | 17029 | 2761 |
SART1,CYLD,TRIP10,XAB2,SUZ12,SF3B1,RAE1,CSNK2A1,USP39,THRAP3,SND1,GTF2F1,RBM17,RPA2,PA2G4,PSMD1,PSMA6,EIF4A3,HUWE1,MCM5,ZNF326,ANXA5,TCEA1,RBM12B,PABPC1,GM2A,LUC7L2,HNRNPM,PRPF19,CDC5L,SNRNP200,CUL3,PRPF3,BRCA1,SRSF5,MCM2,PATL1,SF3A2,SNRPA,DHX15,PSMB3,SRSF1,EPB41,RPA1,SUPT16H,DDX17,CAND1,HNRNPR,CCDC6,RBMX,U2SURP,PRPF4,DDX5,XRCC3,FUS,SNRPG,ISY1-RAB43,ZNF830,SMURF1,NKAPD1,PSMC1,ZMAT3,DDX42 |
| 5.293e-10 | -21.36 | RAB5C (RAB5C, member RAS oncogene family) | protein interactions | 5878 | 152 | 56 | 17029 | 2761 |
CHMP2A,COX5B,IMMT,NDUFS1,RAB11B,PHB2,LAMTOR3,FLOT1,LETMD1,SMARCA4,ARF1,ATP6V1B2,DUSP22,RAB11A,APP,CDC73,TFRC,XPR1,RPA2,RPN1,RAB8A,RAP1A,KDM2A,SLC38A5,TTC3,TTC17,ATP6V0D1,LDHB,STAU1,RAB7A,ATP2C1,VDAC2,LDHA,ATP6V0A1,NDUFA7,VDAC1,CHMP2B,RAB1A,GOSR1,MRPS14,RPA1,STOML2,CHCHD3,SUGP1,TBC1D17,MRPL55,TMED10,BBX,APPL2,CHMP4B,PIEZO1,NDUFS5,H3F3A,CDK2,ARRB2,C2CD5 |
| 5.294e-10 | -21.36 | GO_ORGANONITROGEN_COMPOUND_METABOLIC_PROCESS | MSigDB lists | GO_ORGANONITROGEN_COMPOUND_METABOLIC_PROCESS | 1682 | 343 | 17377 | 2626 |
PPCS,NDUFB6,GXYLT1,MRPS15,HEXB,GLUD1,OAT,EIF1B,RBM4,PABPC4,SLC25A37,RPL23A,EEF2K,UPRT,SLC26A2,SPTSSA,DNMT1,PCBP2,KCNAB2,MKI67,MRPL43,ICMT,SLC25A5,EIF3A,STOML2,RPS27A,RPS14,EIF2D,PRDX5,MRPL27,DHTKD1,MLYCD,COX5A,UQCRH,ST3GAL2,CHPF2,OAZ1,PFKP,B4GALT2,SLC25A33,NDUFV2,COX5B,MRPL9,MUT,MRPS2,DHPS,ADO,GSPT2,CERK,RRM1,B4GALT1,NDUFA4,CYCS,EIF2AK4,PSEN1,NDUFS7,NDUFS4,MCTS1,GNS,PDXP,EIF2S2,ATIC,EFTUD2,MSH2,ATP6V0A2,CYC1,MRPL40,MRPL21,LPCAT1,PABPC1,PPA1,EEF1D,CARS2,EIF5A,EIF3L,NOA1,DHX29,RPS10,RPS24,DCTD,MRPL16,MPG,EIF4H,ABCF1,MTR,ADSS,CAT,EPRS,SLCO4A1,MTHFD2,QARS,DCK,TYW5,LPCAT4,MDH1,SAMD8,GPI,SMPD4,HEXA,MRPL3,EGLN1,KARS,DNMT3A,EIF3D,UROD,OLA1,NIT2,ADPGK,SLC35B2,SLC25A44,CD320,FLAD1,DUT,LPIN2,ADCY9,MRPS27,TALDO1,CLN6,GPD1L,PDCL3,ADCY7,ENPP4,CDC123,RPL38,ATP6V0A1,PFKFB3,NDUFA7,POLG2,TAZ,MAT2A,PPP2CA,EIF3K,ALDH3B1,MRPL55,HINT1,CERS6,PPA2,RPLP1,FTSJ1,MBOAT1,PDXK,B4GALT3,GALK1,RPS2,NDUFS1,MECP2,B4GALT5,MRI1,TKT,SLC25A12,ABHD14B,SECISBP2,SPR,SLC25A43,NEIL2,SLC25A36,MAT2B,ERH,CLIC4,GATC,ITGB8,NDUFA2,RPL17,NDUFB4,CRAT,MRPL54,RPL19,ST8SIA2,GTF2H2,NDUFA3,RPL22L1,LDHB,TK1,GUK1,GALC,RPL8,LDHA,MRPS10,ADSL,RPL27A,PDE3B,ARSK,GUF1,SPPL2B,SLC19A1,SGSH,RPL32,DBI,OAZ2,SLC25A19,PSAP,NDUFS5,CPEB2,SRM,COX15,AGRN,UQCR10,MCCC1,BECN1,MRPL19,BCAT2,MBD4,CREM,PCYOX1L,EIF4A3,GOT2,IMPAD1,SLC44A1,PPCDC,AKR1B1,NDUFB9,EIF5,OGG1,MTPN,MRPL32,ABCC5,LARS,HARS,MRPL12,SLC25A22,ODC1,RPL37,NAGLU,IARS2,QRSL1,CLN3,MRPL13,CHPT1,RPS26,SEPHS2,RPS15,NACA,SDC2,PCSK7,RPL15,ASAH1,COX4I1,B4GALT4,RSAD1,CHKA,GLTP,AHCY,MRPL48,ACAD8,ALDH18A1,ALDH9A1,ABCC1,AMD1,GBA,RPL6,EIF2AK1,THNSL1,EIF2A,EIF4G2,RPL36,ORMDL2,COX7A2L,TBPL1,DTD1,CTSA,PTDSS1,MMACHC,NDUFA5,RPLP2,MDH2,MRPL39,UCK2,UCK1,CHKB,ATP6V1B2,EXT2,PAIP1,RPL11,MRPL50,SEC11A,FARSA,IARS,MRPL34,AHCYL1,TMEM14C,HTRA2,GM2A,RPL29,RPL35,PPT1,HPDL,CPOX,NLN,GLO1,OGDH,NDUFB1,MRPS14,EIF3G,RPS9,PDHX,EIF3H,RPSA,MRPL2,DAP3,IDE,CHCHD1,NDUFA11,FAU,MAPK1,LTA4H,CHID1,SLC25A39,PDF,NADSYN1,GCLM,MRPL42,MRPS26,SUMF1,CHAC2,GFM2,SPPL2A,GSTK1,GART,NDUFV1,RRBP1,NDUFS8,MRPL11,SLC25A1,B3GALT6,TGFB1,AMPD2,CSNK1G2,TUFM,PNPLA8,HAGH,TARS,NEU1,HSPA1B,CTBS,COX8A,IMPDH1,ACAT1,ACADM,SPCS3,IDH3B,PGAM1,SAT2,GCSH |
| 5.361e-10 | -21.35 | GO_REGULATION_OF_PROTEASOMAL_UBIQUITIN_DEPENDENT_PROTEIN_CATABOLIC_PROCESS | MSigDB lists | GO_REGULATION_OF_PROTEASOMAL_UBIQUITIN_DEPENDENT_PROTEIN_CATABOLIC_PROCESS | 141 | 51 | 17377 | 2626 |
ZNF207,GORASP1,DNAJB2,SUMO2,UBXN1,CENPF,NKD2,CSNK2A1,SIRT2,UBQLN2,CCNB1,CSNK1A1,PSEN1,ANKIB1,BCAP31,PARK7,MAD2L2,FBXO22,USP5,FBXO5,RAD23A,RB1,MDM2,PTEN,RAD23B,RNF19A,SENP1,SOCS5,PLK3,PLK1,UBQLN4,PBK,GBA,CUL3,RAB1A,GNA12,KEAP1,HSPBP1,GOLGA2,NSMCE2,SOCS4,XRCC3,DVL1,CLU,RNF14,GEN1,TERF1,ESPL1,CSNK1D,SVIP,RNF114 |
| 5.607e-10 | -21.30 | ELVIDGE_HYPOXIA_DN | MSigDB lists | ELVIDGE_HYPOXIA_DN | 133 | 49 | 17377 | 2626 |
SRM,HSPH1,RRP15,COPA,URB2,TOR3A,SLC29A1,SDF2L1,SLC35B1,GYG1,SLC25A44,POLR3K,SCYL2,PNO1,CHKA,FLAD1,RAB35,ATP6V0A2,CORO1A,LRRC59,BAK1,RPP25,PPIF,EIF5A,IDH3A,DHX29,AMD1,ABCF2,KIAA0930,RANGAP1,OGDH,DNAJA1,ODC1,SRSF1,BRMS1,HHEX,HSPA4,KPNA4,SEC23IP,IDE,KPNA1,CCDC86,NIP7,QRSL1,NCLN,RNF14,MAPK1,PRPF4B,TMEM33 |
| 5.618e-10 | -21.30 | negative regulation of cell cycle process | biological process | GO:0010948 | 342 | 96 | 17256 | 2622 |
ZNF207,CHMP2A,MAX,GPR132,SUZ12,PTTG1,CUL1,CCNB1,FANCI,PSMA6,PCNA,PSMD1,BABAM2,MDM2,CDKN1B,CTDSP2,CARM1,RYBP,PLK1,PLK3,RBX1,PSMA8,BTG2,EHMT1,TAOK1,PCGF6,PSMB7,MRNIP,RRM2,AURKB,BRCA1,CCNF,SOX4,PSMB9,RPS27A,RBL1,PSMD8,PSMD3,E2F4,ZNF268,CHEK2,VPS4A,TFDP2,PSMC1,MIF,CLSPN,CDT1,CENPF,CDK2AP2,BABAM1,BLM,CNOT11,PSMD9,CDC73,MAD2L2,CNOT3,FBXO5,RFWD3,RPA2,CCNK,TFAP4,DTL,PSMD2,RB1,SMC3,PTEN,CENPJ,FBXO7,MSH2,GTSE1,H2AFY,BRD7,BCL2,FBXL7,CNOT6L,TERF2,KAT2A,HMGN5,PRKDC,PSMA1,MEN1,PRMT2,PSMB3,PSMC4,CBX3,CNOT9,TFDP1,PML,E2F1,CNOT6,PKD2,RBBP4,ZNF830,CDK2,ESPL1,TERF1 |
| 5.644e-10 | -21.30 | GSE43863_TH1_VS_LY6C_LOW_CXCR5NEG_EFFECTOR_CD4_TCELL_DN | MSigDB lists | GSE43863_TH1_VS_LY6C_LOW_CXCR5NEG_EFFECTOR_CD4_TCELL_DN | 192 | 63 | 17377 | 2626 |
TMED7,FEZ2,ADD1,CAST,CDK2AP2,MYH9,KLF13,SUMF1,GGA2,HCFC1R1,PARN,LYRM2,HDDC2,CDKN2C,GOLM1,MLX,MED10,INTS7,SH3BP1,HDAC7,SLC44A1,CS,ANP32A,RPN2,SLC38A10,MDFIC,GLE1,MRPL40,GNAI2,FAM3A,GM2A,IMPA2,RPAP3,CPNE1,KDM3B,ADAM17,SEPT9,HELB,BTG2,MRPL43,HTATIP2,BRCA1,ESYT1,CCNF,PRPSAP1,PSMB9,GLOD4,CAT,PON2,HHEX,FBXO21,HSPB11,FNTA,AHNAK,NEK1,CDCA7L,OAZ2,COX7A2L,ZNF436,COX8A,ZFP90,TRAF5,CBX4 |
| 5.868e-10 | -21.26 | peptide metabolic process | biological process | GO:0006518 | 540 | 136 | 17256 | 2622 |
MRPS15,EIF1B,BECN1,RBM4,MRPL19,PARK7,PABPC4,EEF2K,RPL23A,EIF5,MRPL32,MRPL57,LARS,HARS,APH1A,MRPL43,MRPL12,EIF3A,RPL37,GEMIN5,RPS27A,RPS14,MRPL27,EIF2D,IARS2,QRSL1,CLU,MRPL13,RPS26,ZNF598,RPS15,MRPL9,MRPS2,DHPS,GSPT2,PCSK7,RPL15,PSEN1,MCTS1,EIF2S2,EFTUD2,MRPL40,MRPL48,MRPL21,PABPC1,PPA1,EEF1D,CARS2,EIF5A,EIF3L,CPQ,DHX29,NOA1,RPL6,RPS10,RPS24,MRPL16,EIF2A,EIF4H,EIF4G2,ABCF1,RPL36,EPRS,QARS,MRPL3,MMACHC,KARS,CYLD,RWDD1,RPLP2,MRPL39,EIF3D,EFL1,PAIP1,RPL11,MRPL50,SEC11A,FARSA,IARS,MRPL34,MRPS27,RPL29,RPL35,RPL38,NLN,GLO1,NDUFA7,MRPS14,POLG2,RPS9,EIF3G,RPSA,EIF3H,EIF3K,MRPL2,DAP3,IDE,MRPL55,CHCHD1,FTSJ1,RPLP1,PPA2,LTA4H,PDF,GCLM,RPS2,MRPL42,AGO2,MRPS26,SECISBP2,CHAC2,GFM2,SPPL2A,GSTK1,CLIC4,GATC,RPL17,RRBP1,PELO,LTN1,MRPL54,RPL19,MRPL11,GTF2H2,RPL22L1,TUFM,RPL8,MRPS10,GUF1,RPL27A,HAGH,SPPL2B,TARS,RPL32,SPCS3,CPEB2 |
| 6.073e-10 | -21.22 | RPS6KB2 (ribosomal protein S6 kinase B2) | protein interactions | 6199 | 197 | 67 | 17029 | 2761 |
USP7,MAGED1,LYN,PCBP1,SSR1,RPL23A,EEF2K,HNRNPA2B1,PCNA,STRBP,CFL1,TIMM50,CDC37,CCT2,SNRPB,DNAJA1,SLC25A5,CLNS1A,DDX17,KIF2A,PPP2CA,ATP1A1,RPS14,PSMD3,PPM1G,FKBP5,FUS,SINHCAF,PSMC1,PDCD4,TUBB,HSPH1,EWSR1,RPS2,DHX9,DNAJB1,HLA-A,WRNIP1,KIF5B,RPN1,EIF2S2,RPL17,CAPZA1,RTCB,YBX1,RPL19,PTGES3,PPP6R1,RPL22L1,HNRNPM,MSH6,NUDC,PDPK1,PSPC1,RPL8,TUFM,CCT8,PRDX1,XRCC5,MAGED2,LRPPRC,DDX5,ATP5F1A,RUVBL2,PPP6R3,YWHAH,DDB1 |
| 6.137e-10 | -21.21 | GSE40225_WT_VS_RIP_B7X_DIABETIC_MOUSE_PANCREATIC_CD8_TCELL_DN | MSigDB lists | GSE40225_WT_VS_RIP_B7X_DIABETIC_MOUSE_PANCREATIC_CD8_TCELL_DN | 188 | 62 | 17377 | 2626 |
PKP4,H2AFZ,TMEM184B,MDH2,PTTG1,SDF2L1,MAN2B1,UBE4A,TMED3,POMP,SND1,CDIPT,PSMD9,PMVK,PDXDC1,MDM2,IARS,UCHL5,PRC1,YIF1B,MDFIC,ATG13,CLDND1,KNTC1,ALDH18A1,N4BP2,MLST8,BAK1,SRP72,POU2AF1,METTL1,CYFIP1,USO1,MLEC,MAPKAPK3,DENND1B,GBA,JTB,BRCA1,ECH1,ARF4,OPTN,PLD3,CACNB1,TRIM47,CDCA4,IDE,RBM47,UAP1,TWSG1,NEIL3,ACOX1,TFDP1,NAGLU,NFIL3,FTSJ1,HMGB2,KLHDC4,CABLES1,SSSCA1,AAAS,GEMIN7 |
| 6.137e-10 | -21.21 | GSE10239_MEMORY_VS_DAY4.5_EFF_CD8_TCELL_DN | MSigDB lists | GSE10239_MEMORY_VS_DAY4.5_EFF_CD8_TCELL_DN | 188 | 62 | 17377 | 2626 |
RAB14,RPS2,EWSR1,MCM10,MRPL39,ACTR3,ALKBH5,NUP54,RRM1,LAMTOR3,USP39,XPO7,AP3S1,GLRX3,KCMF1,C1GALT1,GRSF1,MCM5,RAD23B,FEM1B,TRA2B,KIF22,STRAP,DRAM2,LUC7L2,SAP30,FDFT1,SRSF10,GINS1,POU2AF1,CLCN3,MLEC,HARS,PSPC1,IDH3A,TEX10,USP42,LRBA,CYP20A1,E2F3,LDHA,SLBP,CCDC34,AURKB,DCUN1D5,DIDO1,KDM1B,MCM2,ANKRD46,CAND1,PRIM1,CBX3,CDC16,CCDC6,CDCA5,RWDD4,QRSL1,SPCS3,NAA20,RRS1,PDLIM5,TSTD2 |
| 6.265e-10 | -21.19 | nucleoside phosphate binding | molecular function | GO:1901265 | 2093 | 419 | 17224 | 2647 |
RAB14,ABCC10,TAP1,DHX8,GLUD1,UBE2I,EEF2K,KIFC1,CDK5,NEK6,CYB5RL,RAB4A,ATP13A3,PDS5B,DNM2,UPRT,SUCLG2,CRY2,MAST2,DNMT1,PLK3,RHOBTB3,NRAS,AKT2,PBK,KIF15,MKI67,DDX20,SMC2,AURKB,MCM2,RFC2,RAB22A,RAB2B,ARF4,MAP3K4,MKNK1,KIF18B,LIMK1,MYO18A,RNASEL,LONP2,PFKP,DDX42,DDX58,HSPH1,RECQL,CHTF18,RHOC,TRIO,GSPT2,PRKAA1,DHX9,RRM1,RAB23,CERK,KIF23,TOP2B,EIF2AK4,RTKN,DDX56,SMC3,MCM5,EFTUD2,CTPS1,MSH2,DAPK1,RTCB,PIKFYVE,GNAI2,PHKG2,UBE2QL1,CARS2,DDX28,COQ8A,MAPKAPK3,DHX29,NOA1,PGS1,TYW1,GTPBP4,PIP4K2C,SEPT8,RIT1,PKM,ABCF1,MAP2K2,CCT8,RHOB,PI4K2A,XRCC5,CAT,ADSS,EPRS,HSPBP1,NSF,CSK,CSNK1G1,DCK,QARS,ACLY,MDH1,MAP3K5,CDK2,NRBP1,ACSF2,ZC3HAV1,RHOG,KARS,ABCA3,TP53RK,RAB11B,RPS6KA1,RAF1,CHD1L,KIAA0232,RAC1,ACTR3,OLA1,TPX2,MYH9,EFL1,PRKACA,SDHA,CBWD5,FLAD1,DECR1,RAB21,PRKD3,ATP2A2,RALB,UBA5,ADCY9,CLCN6,SEPT11,TAP2,AQR,GPD1L,ARL5A,CDK12,ADCY7,CCT2,ULK3,ATP13A1,IDH3A,MAP4K4,TAOK1,POLR2D,VDAC2,PFKFB3,GALK2,PKMYT1,DNAJA1,RAB1A,MAT2A,DHX57,DDX17,KIF2A,RAD51C,HSPA4,JAK1,HINT1,RAB24,GUCY1B1,NT5C3B,HIPK2,CBWD1,PDXK,PPP5C,CSNK1D,TUBB,DYNC1LI2,RHEBL1,PRPF4B,POLQ,GALK1,ANXA6,TWNK,MECP2,IP6K2,ATP5F1B,BLM,SPR,PMVK,IFT27,RAB11A,PIP5K1C,SRXN1,ERH,GATC,CBWD2,ARF5,TTLL12,MAP3K14,UBE2M,MSH6,SMC4,LDHB,PDPK1,TK1,DDX24,GUK1,NEK7,LDHA,BMS1,RHOT1,DDX39A,GUF1,KIF11,MARK2,MYO1F,GNA12,KIF18A,POLE,TTLL4,ACOX1,MAPK6,NAXE,ASNA1,DDX5,DDX52,DDX47,UBE2E2,ST13,YTHDC2,MCCC1,CSNK2A1,UBE2Q1,UBE2Z,ABCB10,KIF2C,SIRT2,MAPK14,PAPOLA,ABL2,RAB8A,RAP1A,CDC42,EIF4A3,RAB35,TRMU,XRCC2,KIF22,RP2,EIF5,ABCC5,SRPK2,PLK1,LARS,SNRNP200,SEPT9,HARS,TLK1,CDC6,RAB5B,LSG1,STK17B,DHX15,RHEB,SEPT1,CHD3,IARS2,CRCP,BAZ1B,QRSL1,ACTB,STK11,CHEK2,DHFR2,VPS4A,ROCK1,PSMC1,SEPHS2,UBE2D3,CDK13,RAB6A,THRAP3,CHKA,UBE2Q2,MBD2,KIF13B,SLC27A4,AHCY,ACAD8,ALDH18A1,N4BP2,CSNK1G3,ABCC1,NTPCR,AACS,NQO2,ACSL3,KRAS,MAP4K3,EIF2AK1,UBE4B,SEPT7,DAPK3,BBS12,MASTL,PSMC4,GNAS,PRPS2,NLRC5,SIL1,RUVBL2,ATP5F1A,EHD4,MYO9A,MBD1,MMACHC,SUCLG1,UGP2,MRPL39,PMS2,UCK2,SMARCA4,RRAGC,UCK1,CHKB,ORC1,ATP6V1B2,LYN,TWF2,CHD1,MIEF1,FARSA,ZBTB21,PDK2,PSMA6,IARS,DUS4L,SAR1A,NVL,KIF14,CYB5R1,CHTOP,SCYL3,ACSL5,CLCN3,CGAS,RAB7A,KDM1B,ARL5B,MBD3,GFER,RAD54B,DAP3,ATP1A1,IDE,DUS3L,DHX16,CLK3,FASTK,STK38,XRCC3,MAPK1,ABCA1,RAD51D,NADSYN1,KIF3B,SHPRH,TOR3A,SCYL1,GNE,SMC6,ARFIP2,ARF1,MYO9B,CDK11B,CSNK1A1,RMI1,SCYL2,PIP4K2A,GFM2,WRNIP1,KIF5B,GTPBP3,FGFR3,STARD9,NDUFV1,GART,GRK2,DUS2,ABCD1,DDX31,CAMK2G,MICAL3,MYO5A,RNLS,CSNK1G2,RHOA,PRKDC,HELB,BTAF1,ATP2C1,ABCF2,TUFM,PRKAR1B,NADK2,PNPLA8,RHOT2,CDK11A,TARS,MAPK3,DDX23,HSPA1B,MFN2,RAB18,NEK1,UPF1,ATAD2,ACADM,IDH3B,RPS6KC1,UBE2C,HRAS,HIPK3,TYW1B |
| 6.272e-10 | -21.19 | RNA localization | biological process | GO:0006403 | 209 | 67 | 17256 | 2622 |
NDC1,TOMM20,NUP188,SARNP,THOC1,RBM8A,ALKBH5,AGFG1,HNRNPA2B1,AHCTF1,NUP210,SNUPN,EIF4A3,ZNHIT6,SRSF4,NUP107,NUP153,CHTOP,ZC3H3,SEH1L,FYTTD1,CCT2,NXT1,POLR2D,RNPS1,SLBP,NUP155,BICD2,NUTF2,RPSA,SRSF1,IWS1,HHEX,RRS1,NMD3,AAAS,NXT2,RPS15,CDC40,RAE1,SRSF6,NUP54,FLOT1,DHX9,XPO7,PRPF18,NUP205,UPF2,GLE1,CPSF4,MVP,FBL,NUP85,EIF5A,SRSF11,SRSF5,DDX39A,SYMPK,NPIPA1,TSC1,UPF1,LRPPRC,KHSRP,NUP62,SRSF3,YY1,NUP58 |
| 6.282e-10 | -21.19 | large_intestine-colon-carcinoma-adenocarcinoma | COSMIC cancer mutations | large_intestine-colon-carcinoma-adenocarcinoma | 16933 | 2561 | 17385 | 2587 |
HECA,ZBTB10,ABCC10,HEXB,TGOLN2,CCNL2,FBXO22,EEF2K,THAP4,RAD23B,ATP13A3,DNM2,ZNRD1,FTSJ3,USP34,CCDC57,ERCC1,NRAS,EHMT1,KIF15,HNRNPF,WDHD1,MIER2,DIDO1,MCM2,RAB22A,SMAD2,MID1IP1,RPS27A,MYO18A,OGT,MPV17,COX5A,SMAD1,ZNF75A,ANXA11,SLC25A33,ZNF720,SEC61G,GGA1,MUM1,CCZ1,TRIO,CUTA,RAB23,KCTD17,HAUS4,EIF2AK4,APH1B,PARN,CDC73,MYL6B,ATG4A,TMEM179B,ERV3-1,PDXP,SMC3,C4orf3,GEMIN4,MVP,NUP85,PPP6R1,PABPC1,NSUN4,PPA1,IFRD1,AGGF1,FOXK1,RBM42,GTPBP4,MAP7D1,MRPL16,ELK1,EIF4H,RDH11,MAGED2,KPNA1,ETS2,TYW5,WIPI2,RUFY3,PDLIM5,ACSF2,EXOC3,RHOG,STARD7,C5orf30,VTI1A,INO80E,SLC35B2,LCLAT1,RCOR3,CPNE3,KIAA1147,RBM23,ZNF420,AHCTF1,TBC1D22A,TBC1D14,GMEB1,NSFL1C,SEPT11,GPD1L,ZC3H3,ARL5A,PDCL3,SNX8,ERMP1,EID1,IDH3A,POLR2D,HTATIP2,MEF2D,TMEM147,GSTCD,TANC1,MAT2A,VPS26B,CORO1C,NSMCE2,CAMKMT,PPP5C,PITRM1,TUBB,COMMD10,ZNF445,SRSF6,HABP4,CCM2,FLOT1,BTN3A1,ATG2B,ABHD14B,PPP1R3B,GOLM1,ZBTB45,HUWE1,ZNF260,NAA50,ANXA5,LTN1,KANSL2,UBE3B,NAP1L4,ZNF710,ST8SIA2,RPL22L1,MED22,SPTAN1,STAU1,DDX24,TCTEX1D2,TACC1,MRS2,LDHA,HEBP2,LLPH,RAB3IP,TTC33,PICALM,SH3BP5,SLC19A1,ACOX1,FAM3C,AEN,PARP10,YWHAH,THAP5,GPATCH4,FAM129A,TRIM11,YTHDC2,SNX15,RBM8A,ENSA,NENF,SND1,RUFY1,TRIM65,ZER1,PRNP,KRR1,RAB8A,NUP210,NT5DC1,NOC2L,EIF5,TACC3,RYBP,VPS13B,PTPN18,MIOS,SNRPB,MBLAC2,CDC6,UTP3,PBRM1,ODC1,USP21,TRAM2,FBXO28,BCL7C,ARRDC1,ADAM9,DVL1,NUMB,ZNF564,FUBP1,C1orf74,CTU2,PARP12,ZCCHC9,CENPF,LAMTOR3,CHCHD2,NCKAP1,LYRM2,RSAD1,TNS3,SUB1,RINL,SSBP3,KIF13B,MBD2,XPA,AHCY,RBM3,GLE1,MRPL48,LRSAM1,HDHD2,NTPCR,NSDHL,AMD1,CAMSAP1,ZNF761,METTL22,ICAM2,STYXL1,APPL1,BBS12,ANKRD46,RXRB,SDHB,PCM1,GALNT2,TMEM168,NLRC5,RUVBL2,MYO9A,BTBD10,CCNB2,USP7,GLT8D1,RPLP2,SUCLG1,ARID2,TMX4,SLC2A1,ATP6V1B2,PCBP1,LYN,BCAP31,VAV1,TMEM69,MRPL50,PSMA6,ZNF473,ZNF302,BRPF3,TARDBP,BCAP29,CTDSP2,PRPF19,PPIF,KDM3B,MND1,CLCN3,BIRC3,RAB7A,ANKRD33B,PPIE,CHMP2B,VDAC1,EIF3H,TMEM201,GLOD4,IDE,DHX16,UHRF2,XRCC3,CHMP4B,PARD3,BCL2L12,MCM10,C19orf53,KLHL21,PDAP1,CDCA8,TMX3,GTF3A,ARF1,SLC12A9,TUBGCP2,DNAJB9,HOMER1,WBP1L,POLR1B,RNF5,RBM15B,PPAN,RHOA,RPRD1A,BTAF1,TOP3A,ARHGEF12,PCGF1,DDX23,RAB18,CACNB1,TRIM26,PDCD6,ATP6V1D,L3MBTL3,FAM110A,NEIL3,CTBS,BBX,IMPDH1,TAF12,NR2F2,PGAM1,HIPK3,IFI16,TXN,NUP188,H2AFZ,PNISR,TMEM203,PRKCSH,USP39,UBE2I,PARK7,SLC25A37,ASPHD2,ZNF428,RAB4A,TRA2B,SUCLG2,CISD2,TAF5L,SMARCE1,ZNF800,CDC5L,ZNF524,SGCE,OSBP2,NSUN2,USP22,CLNS1A,EIF3A,ZMYM3,DOT1L,IWS1,ANKRD10,WAS,KIF18B,TPP2,C1orf109,ZMAT3,B4GALT2,PRPF38B,RECQL,C9orf78,EWSR1,GADD45G,RRM1,ACAP1,B4GALT1,CYCS,FAM136A,SUPT7L,TMEM165,CNOT3,NPLOC4,SPAG5,WDR48,RTKN,CEP104,EXOSC7,KLHL5,LRRC8D,PPP4R1,MSH2,PIGG,FBXL7,OSTF1,MRPL40,TNRC18,SYTL3,FAM171A1,APOL1,EIF5A,GCC2,PRIM2,ELL2,RDH10,MFNG,RPS24,GORASP2,CAPZA2,ADRB2,CCT8,MTR,PHF6,PFDN5,SLCO4A1,TTC13,GOLGA2,RBMX,MED15,PIAS2,APPL2,SAMD8,CDKN2A,NUDT3,ZNF511,ATXN3,RAF1,KIAA0232,C2orf49,EPM2A,CD320,CCNA2,MTMR4,BRI3,TP53BP2,AQR,RBM12B,ILKAP,CDK12,SAP30,BRD4,DRAP1,NARF,LRRC8A,ELP4,ABHD11,PKMYT1,ASB13,SERP1,TRIM28,SUPT16H,EIF3K,CHMP4A,CBWD1,ATF6,XRCC4,ADAM23,PRPF4B,NDUFS1,DEPDC1,MECP2,SECISBP2,HMG20A,WWP2,JAKMIP1,SLC25A36,CCNK,DNAJC8,AXIN2,CITED2,JMJD4,ANKRD37,KAT2A,TMEM126B,RABIF,ADSL,PACS1,BMS1,KCNQ1,OTUD3,ARSK,MACF1,KIF11,COMMD4,KLF6,SMAP2,FADD,SH3GLB1,MYO1F,CBX3,TMEM127,INF2,PPP1R11,DUSP11,DDX5,WDR62,TAF6,ESPL1,PURA,DDB1,DEF6,IPO4,FAM83G,UBL3,NAT9,PIGM,LYRM4,GPR132,UBE2Q1,PTP4A3,BRIX1,MRPL19,ZNF696,SF3B2,PCYOX1L,CDC42,SYNM,GOT2,JAZF1,HADHB,RPF2,SLC35C2,CNNM3,CARM1,SRPK2,WDR41,LARS,ZCCHC10,CCDC138,LRBA,TMEM216,SUMF2,KMT2C,OGFR,PRPSAP1,ASF1B,RPL37,MAN2A2,EIF4ENIF1,NIP7,U2SURP,MIA2,ZNF268,VPS4A,ATP6V0E1,PPP1R2,PM20D2,XPNPEP3,RGS2,LYAR,FAM89B,POLR2I,TRAFD1,SUGP2,GBA,EIF2A,SYVN1,DAPK3,ARHGAP15,MASTL,UAP1,NFIL3,FN3KRP,YWHAZ,CTSA,TMEM14A,TOB1,TSEN15,ADNP2,TCF12,PRKAB1,MDH2,SMARCA4,ORC1,RRN3,UBXN2A,IARS,CD3EAP,KIF14,EXOSC1,CS,CLTB,DNAL4,CSTF1,POU2AF1,UBQLN4,NXT1,HPDL,PGGT1B,SELPLG,SMU1,ATXN1,GLO1,OGDH,BICD2,CADM1,EDEM2,HERPUD2,TOLLIP,FANCE,MBD3,PDHX,RPS9,ALKBH6,SURF4,DUS3L,ARNTL,ANP32E,FKBP5,TMEM101,CCDC125,ABCA1,PDCD2L,GCLM,RAE1,DCTN2,NUP54,CHIC2,PAWR,MXD4,DCUN1D4,PIP4K2A,XPR1,FERMT3,KIF5B,KLHL20,SEC24C,RRBP1,ARHGEF2,ANP32A,LDLRAD3,STAT3,MYO5A,NIPAL3,AMPD2,TXNL1,PHF20L1,DCAF6,FAM49B,TMEM39A,ATP2C1,RFFL,COG1,RCOR1,PRMT2,TFEB,LEMD2,UPF1,ELMO1,ZC3H7B,DTX4,ZMIZ1,TERF1,HRAS,CCDC93,FGFR1OP,TMED7,PIGQ,AGPAT1,CNTROB,PPP1R16B,MIS12,GSDMB,TTC9C,PDS5B,NUP153,SENP1,PGAP2,TMEM115,PLEKHM3,DCUN1D5,PLEKHF2,BRMS1,PWWP2B,TRIM47,WDR11,AXIN1,SMG9,TRIM52,LONP2,NDUFV2,PHF23,CERK,SLC4A2,EZH1,ITGB5,LMNA,MCTS1,DDX56,EIF2S2,SLC38A5,FOXN2,CARS2,PRRC2A,C16orf72,RB1CC1,ZMYND11,PGS1,MYBL2,UHRF1BP1,SRSF5,MPG,MATR3,CYB5A,NCDN,POLR2J,SETD3,TEX30,PTAR1,CNOT6,NDE1,EGLN1,ZNF207,ANKRD27,ABCA3,SARNP,IVNS1ABP,RMI2,MON1B,TMEM97,NIT2,NUF2,ZNF267,TCF19,TMEM161B,KTN1,APP,PRKD3,CLUAP1,ATP2A2,UTP18,GRSF1,DUT,ZCCHC2,ANAPC7,RNF19A,FAM76B,CLN6,TMEM9,GCC1,RNF169,ADCY7,ATP6V1G1,ENPP4,RNPS1,CDCA2,FKBP3,GPR137,DDX17,CHCHD3,PEX5,CDC16,HIPK2,MBOAT1,TICAM1,PDXK,ZBTB11,ANXA6,TMBIM4,GMCL1,UBE4A,IL21R,ETS1,WRB,ZNF92,PNO1,CAPN2,ADD3,SUV39H2,TTLL12,TPCN1,TMX1,HNRNPM,LYPLA2,MFSD12,LDHB,PPP3CA,NUDT8,POLK,JTB,EMP3,MTMR12,ZP3,PDE3B,KIF18A,CCDC6,WNT5B,MAPK6,C4orf46,LY75,SLC25A19,RGL1,PSAP,WDR76,IGBP1,FAF1,SNAPIN,COX15,THOC1,AGRN,GNPDA1,GPBP1L1,PPP1R15B,CSNK2A1,EBNA1BP2,GIT2,BIRC2,ATPAF1,DLG5,ABL2,XRCC2,ZFYVE27,MCMBP,PTPRK,CDC37,SP3,METTL1,EXOSC6,HARS,GMFB,ESYT1,ANLN,RAB5B,RHEB,DPYSL3,TBC1D17,TIMM13,CDCA4,TONSL,NRM,NAGLU,ACTB,ZNF45,TMUB1,CTCF,ASAH1,DOCK11,CRLF3,ASXL2,LRRC14,NUS1,SLC27A4,AFF1,MDFIC,MAML1,CYTH1,NQO2,UTP15,EIF2AK1,EIF4G2,ZDHHC3,MOSPD3,ITPRIPL1,CDC27,SNAP23,TBPL1,PRMT7,KCTD7,NDUFA5,CYLD,UGP2,DYNLL1,COPE,HCFC1R1,ZADH2,GGPS1,RPAIN,RAD23A,ATP6V0B,PDK2,STRBP,DUS4L,MRPL34,PDCD2,SAP30L,CLPTM1,SLC39A9,RPL29,RPL35,BTG2,DNAJC9,FRAT2,MTMR6,NFATC2,KDM1B,ARL5B,USP36,CCDC127,MRPL2,ATP1A1,CLK3,MAFK,PSMD3,NDUFA11,CEP55,ZNF436,DNAJC17,NCOA1,SLC25A39,ZC3HC1,ZNF146,ATXN7L2,CDC40,SMAP1,GOLIM4,RRP15,DAP,GNE,SMC6,ARFIP2,NKRF,CHAC2,BZW2,WRNIP1,SS18L1,CENPM,PTGES3,CAMK2G,MLEC,ZNF202,PPWD1,FAM50B,RHOT2,NEU1,TPD52L2,GOLGA7,TWSG1,PGRMC1,GLG1,FAM126A,RPS6KC1,UBE2C,PPCS,NDUFB6,TMEM41B,ZDHHC8,PLXNA1,CCNB1,SLC20A1,COMMD6,ABHD14A,POLR3K,C14orf119,ASAP2,SNUPN,CNPY4,TFG,PLCL2,SEH1L,ATG9A,PBK,MKI67,DDX20,AMDHD2,GALNT7,SLC17A5,CCNF,FOXRED1,RBM47,PTER,WDR4,DHTKD1,TRAF5,HDAC2,PWWP2A,HSPH1,LIME1,MAPRE1,CHTF18,ADO,KIF23,SLC35B1,NOTCH2,PMF1,COPG2,JMY,FKBP1A,SLC31A1,SNX18,ATIC,CTPS1,ATP6V0A2,PIKFYVE,RNF135,LPCAT1,EEF1D,TMED2,FTL,PHF10,DDX28,ZNF84,SIGMAR1,PIP4K2C,FAM133B,RIT1,PLEC,KDM3A,SF3A2,FAS,EPRS,ZNF777,TMEM54,QARS,PPP3R1,TCOF1,NRBP1,CABLES1,DNMT3A,RWDD1,CKLF,TRIP10,SF3B1,RPS6KA1,CAST,SUZ12,RAC1,GPR89A,OLA1,SNN,GNB2,FLAD1,APLP2,KDM2A,TNPO2,CDKN1B,TALDO1,GPX4,ATP13A1,RFC3,MAPRE2,ERF,CUL3,SLBP,KIAA1586,H2AFV,POLG2,GAR1,PSMB9,DHX57,NSA2,HSPA4,MRPL55,JAK1,TBL3,SEL1L,H2AFX,KLHDC4,B4GALT3,PDCD11,ATMIN,POLQ,POU3F2,OTUD5,NCOR2,ANKRD13D,PKP4,SCAMP3,BABAM1,CDCA3,SLC25A12,BLM,TMCC3,GTF2F1,CRAT,AHSA1,PRC1,UPF2,COPS7B,SLC38A10,CNOT6L,CNPY3,UBE2M,IFT46,TMEM160,TSHZ1,ZFP64,STRIP1,DENND4C,DENND1B,WDR18,RPL8,ILF3,LRRC1,RHOT1,MARK2,TSR2,ECH1,PRDX1,PLD3,NUCB1,FBXO21,GNA12,C1orf131,PRDX3,PFDN4,HNRNPH3,STX18,TFDP1,KHSRP,ASNA1,CPEB2,SSSCA1,BYSL,VPS29,S100PBP,MIB2,IER2,PTMS,NOP2,UBN1,NF1,DCAF15,FLYWCH2,ALKBH5,MOGS,UBE2Z,TAF6L,MAPK14,BECN1,SNAPC4,RNF103,BCAT2,MBD4,C18orf32,METTL14,ZNHIT6,IMPAD1,RCSD1,PHTF1,SRI,KIF22,ZBTB22,NFU1,OGG1,TRIM14,ELOF1,COPS8,FYTTD1,TRIM8,RRM2,SOX4,ABHD5,UBTF,CXXC4,PAF1,UEVLD,SPATA2,PQBP1,IARS2,ATXN2L,GALNT10,STARD3NL,RPS15,PIGN,AGTRAP,CIB1,XPO7,SRRT,ZNF449,CAPZA1,GLTP,BCL2,KIFAP3,N4BP2,HP1BP3,VOPP1,THNSL1,ISG15,CAND1,C22orf46,GNAS,TSC1,RBM25,CDCA5,ZFP90,NANP,RBBP4,ZBTB24,SMARCD1,MBD1,WASF2,MMACHC,TOMM20,IFI27L1,GNPNAT1,MPHOSPH8,HNRNPUL2,CHD1,MEAF6,C2orf68,CCDC50,AKAP8,PARL,RPN2,CHTOP,FAM3A,F2R,SCYL3,TMEM14C,ABI1,HTRA2,MOSPD1,RLIM,FAM172A,ZNF500,PSMB7,NLN,WIPF1,BOLA1,BUD13,NDUFB1,PEF1,EIF3G,BTBD1,TAB2,CHCHD1,TULP3,WDR59,CANT1,SCARB1,GAS2,USP11,SMURF1,TSPAN5,PPP2R2D,CDS2,MAGEH1,MRPL42,EYA1,CDK2AP2,MRPS26,LETMD1,KLF13,HDDC2,RGS1,MAN1A1,FBXO5,GART,PELO,TANK,BRD7,MRPL11,SAMD4B,ZDHHC18,GTF3C6,POLR3GL,WDR81,MEN1,ZNF407,MFN2,COX8A,ZRANB2,MBD6,SRSF3,ATP6V1C1,IDH3B,TATDN1,TSC2,LACTB2,CMTM6,RBM4,ANKRD39,ZNF275,RPL23A,CDKN2C,NAPG,USF1,DNAAF2,MECR,AP1M1,UPRT,CRY2,ECD,RNF26,TIPARP,LRRC59,ANKRD9,MGAT5,RHBDD2,BAK1,ZNF559,RHOBTB3,GABPA,NUTF2,WBP1,GINS4,ARF4,KRIT1,BOLA3,AHNAK,RAD18,PDRG1,RNASEL,CHPF2,OAZ1,SMNDC1,PDCD4,NXT2,HIVEP3,KIAA0100,CLSPN,RHOC,DHX9,PDCD7,PSMD9,HAUS2,COPB2,CD59,TFAP4,RNFT1,RIMS3,MEGF8,EFTUD2,FBXO7,MRPL21,CPSF4,PHKG2,LUC7L2,SRSF11,EIF3L,MTA2,TYW1,USP10,ITM2A,SSR2,BCLAF1,MTX1,SFXN5,FNTA,PDLIM1,TXNDC16,TMEM159,ZNF830,MRPL3,ALS2,TRIM41,KARS,NQO1,POC1A,PTTG1,ANK3,TPX2,TBC1D13,DAZAP2,STMN1,GLRX3,C19orf48,CBWD5,REPS1,ABHD16A,FBXL6,SH3BP1,MTA1,UBA5,CLCN6,INTS12,C8orf59,RPRD1B,CGGBP1,CPNE1,SEC61B,POLR2L,FAM118B,GOPC,CRNKL1,E2F3,CIRBP,RPL38,PFKFB3,GORAB,RAB1A,GIGYF1,TMEM184C,PPP2CA,KIF2A,CCDC14,LSM6,RNF38,DMWD,SNRPG,CENPBD1,USP13,MZT1,ZFP91,TRMT6,IP6K2,WDR5,SLC25A43,PMVK,IFT27,RRP36,NEIL2,SRXN1,RPA2,PSMD2,CLIC4,PDCD10,ITGB8,CBWD2,COQ4,ARF5,ARHGEF1,FBXL19,GTF2H2,TTPAL,UTP20,MAGT1,GPS2,DBI,MRFAP1L1,SSNA1,CD81,TMEM131,WDR13,FANCI,PAPOLA,CREM,FANCL,TET3,GLIS2,IL6ST,INTS1,POP7,SLC44A1,MTPN,ASB6,PLK1,RPP25,SEPT9,CELSR2,RBX1,APH1A,RAD51AP1,ZBED5,CKAP2L,PSMG1,UBE2V1,IL12RB1,EAF2,KRTCAP2,LUC7L,LSG1,NECAP2,C1orf122,TRIM4,ALG3,AGPAT2,CHD3,ZNF367,E2F4,PRPF4,KPNA2,BEND6,CLN3,DNAJC30,FAM208A,NGLY1,POT1,MYL12B,CCDC137,RMND5A,HJURP,PHB2,FAM53C,DNAJB2,NKD2,SDC2,KLC1,CDK13,ADCK5,COX4I1,RAB6A,DNAJB1,ARID1B,C1GALT1,MLX,UBE2Q2,CCP110,ZNF746,ARL6IP1,CTR9,NIPSNAP1,ABHD2,DCAF8,ACSL3,LDB1,MAP4K3,ARMC8,RBM38,IRF5,NMT2,RPL36,HAUS8,MBIP,ORMDL2,COX7A2L,ZDHHC7,FAM122A,SIL1,DTD1,UNC13C,BCCIP,SART1,TRAF7,NDUFAF2,TOR1AIP1,ZNF416,LAGE3,TM9SF3,ZFYVE21,RRAGC,ZNF121,OIP5,NRF1,WDR44,PIN1,PPME1,EFCAB11,RPAP1,CABLES2,TOP1MT,LMAN1,AHCYL1,STRAP,SPSB3,ZNF583,SNX25,ARHGAP17,POLR2G,ZNF780B,KIAA0040,PPT1,NUP155,DCLRE1C,MRPS14,RHBDF2,SUGP1,RBL1,FASTK,UBXN2B,STK38,AP1S1,SPRYD4,SLC22A23,H3F3A,CHID1,SMAD4,RAD51D,SLC30A9,NADSYN1,UNK,CMAS,HMGN3,NCAPG,SCYL2,FZD6,HERC3,GTPBP3,CTSS,ORC3,RNLS,YTHDC1,ACP2,CSRP1,HMGN5,METTL5,ABCF2,TUFM,RANGAP1,PNPLA8,HAGH,API5,ZFR,SEC23IP,E2F1,USP20,TMEM219,RBPJ,MAX,PDCD6IP,LUZP1,GXYLT1,ADAM10,CXXC1,TSC22D3,AP3M2,CUL1,GYG1,NANS,OAT,MYEF2,ANKRD26,PA2G4,NOL11,FIZ1,ZNF200,MARCH2,SLC26A2,SRP72,KLF10,LACTB,RFC2,CBFB,RAB2B,PRIM1,MAP3K4,HHEX,RPS14,LUC7L3,MAP4,MRPL27,BTF3,PTPDC1,CCDC59,NMD3,PTOV1,COX5B,DNAJC5,SCOC,DHPS,POLR2K,ANKH,VAV2,C16orf87,PRKAA1,GSPT2,DLGAP4,TATDN3,PXMP2,PRPF39,PSEN1,ZNF79,PDXDC1,VPS25,NDUFS7,YY1AP1,C12orf10,FAM192A,RPN1,LHX8,ARPC5,ZNRF2,DAPK1,TPST1,PIK3IP1,CYC1,SOCS5,FDFT1,PIGT,WDR1,EMB,ZNF574,C1orf35,EXOSC9,ARID1A,PTTG1IP,C9orf40,FXR1,GOSR1,MAP2K2,TWISTNB,AKAP1,XRCC5,HMGN2,PI4K2A,SEC31A,CAT,DERL1,HSPBP1,MTHFD2,CEBPG,ARAP1,FAM83D,USP32,CABIN1,SMPD4,GPI,CYTIP,TP53RK,REPS2,RAB11B,UROD,SLC39A13,POMP,BCL2L1,NUDT19,DECR1,RALB,SIAH1,LPIN2,ADCY9,SOCS6,MRPS27,TTC3,RNASEH2A,CFL1,ANKLE2,CDC123,OAF,VDAC2,EDF1,ERC1,EML4,AMZ2,ANKZF1,ZNF282,RAD51C,DSN1,DDOST,HINT1,DGCR8,SAFB,HAGHL,LMBR1,RWDD4,FTSJ1,NCLN,BEND3,EYA2,DYNC1LI2,B4GALT5,SLC41A1,MANBA,TKT,FAM76A,CBLL1,ARGLU1,LANCL1,POFUT1,FAM8A1,HEATR5B,HLA-A,EBP,RFWD3,NDUFA2,FUT8,FJX1,BTF3L4,PTPN11,MRPL54,FEM1B,RPL19,CNN2,NDUFA3,MTX2,MSH6,PDLIM2,LONRF3,RFXANK,FBXO9,GUF1,RPL32,ZHX1,OAZ2,NDUFS5,WDR91,HIGD2A,ZBED3,RORB,POLA2,ZNF76,MTX3,COPA,UQCR10,HMGXB3,PHRF1,ABCB10,COMMD5,MAP1LC3B,DST,SIVA1,RAB35,GPATCH1,TCEA1,DRAM2,DEAF1,TRAPPC13,SNRNP200,NCK1,LAP3,VHL,SREK1,ARHGDIB,PITPNB,HSPB11,BRWD1,PPM1G,SH3GLB2,CRCP,BAZ1B,CAB39,ACBD4,STK11,CLU,CHEK2,ZSWIM3,TSTD2,MRPL13,CHPT1,DCAF5,CAPN1,UBE2D3,NSMCE4A,PPP1R12A,ZCCHC8,GORASP1,UBXN1,NACA,C19orf25,PCSK7,EPN1,RPL15,THRAP3,TTF1,QSOX2,PRPF18,NUP205,CHKA,DTL,MED10,ZRANB1,MCPH1,SLC12A2,ATP6V0D1,CSNK1G3,CREG1,NUDT4,RPL6,VKORC1,SLTM,EVC2,KLHL15,SIAH2,SLC16A1,EHD4,SNRNP70,C11orf1,APOL2,N4BP2L2,SNX27,CHMP2A,CORO7,FEZ2,UCK2,PMS2,UCK1,CLCC1,EXT2,MXD1,USP5,HNRNPA2B1,SAP130,NVL,PPP6C,CYB5R1,ZNF770,EBAG9,RNF25,PCGF6,METTL2A,FAM72B,PON2,HNRNPR,STAT6,HPS5,MAPK1,BRD9,TMEM33,NAT14,DNAJC2,TRIP12,SHPRH,SCYL1,VPS45,MYO9B,GFM2,SPPL2A,FASTKD3,FGFR3,MZT2A,PPIG,ZDHHC13,TMEM99,H2AFY,ATG13,NDUFS8,ERI3,FBL,FRMD8,SLC35A1,MICAL3,TGFB1,B3GALT6,ELOVL5,HEMK1,TIMMDC1,HELB,PSPC1,MIER1,SCFD2,NDRG3,ARL17A,CDK11A,MTMR3,MEGF9,ACAT1,CENPT,PLOD3,RAB3IL1,ZSWIM6,RAB14,ADD1,MRPS15,KDM4A,XIAP,DHX8,GLUD1,ANKRD23,PABPC4,CALM2,CDK5,PSMD1,NEK6,NSRP1,RABGAP1L,SRSF4,FNIP2,KCNAB2,PCBP2,MLST8,PLK3,ZNF672,HSDL1,MRPL43,TOPORS,MCL1,SMC2,PPFIA3,ICMT,SLC50A1,STOML2,LIMK1,ZNF689,PRDX5,ATE1,MLYCD,ATP6V0C,ST3GAL2,FBXL3,TFDP2,E2F2,PFKP,AAAS,DDX42,SSRP1,MRPL9,MRPS2,STRN4,TOP2B,ZNRF3,TMED3,DDRGK1,RAVER2,GNS,INTS7,INPP5A,MCM5,PHF14,ZNF326,UBE2QL1,NAGPA,TIMM8B,ETV3,TSPYL4,TSPAN31,DHX29,TEX10,MAN1B1,RPS10,CBFA2T2,ABCF1,RHOB,LRRC14B,DTWD1,PTPRF,SCARB2,OSBPL11,CCDC86,DUSP3,SLAIN1,MDH1,HEXA,RNF139,SNX14,ZNF296,TRERF1,UBR2,CHD1L,ACTR3,WDTC1,MYH9,CREBL2,NIPA2,PRKACA,SAFB2,ANKIB1,STAM,ARL6IP6,RAB21,SP100,ZKSCAN1,DDA1,NUP107,ANKRD13C,MAVS,CEP63,TMEM136,RBM15,ATF2,DCTN1,SHOC2,PSRC1,MAP4K4,WBP2,ATP6V0A1,NUSAP1,NDUFA7,DNAJA1,TAZ,C19orf54,TAF2,SEC61A1,WDR7,RPLP1,CBLN2,RBMS1,FUS,GEN1,LRP8,COIL,LRCH1,GALK1,ZNF786,RPS2,SESTD1,TRAK1,JMJD6,SIKE1,AKT1S1,KRI1,FBXO3,ERH,GATC,NDUFB4,PPP1R8,PRDM4,GTSE1,GEMIN6,DCP1A,SGCB,S100A6,IMPA2,NUDC,PDPK1,TK1,GUK1,TNFAIP3,GALC,ZNF512,KIAA0930,MRPS10,DDX39A,RPA1,ZNF862,ZNF180,KEAP1,POLE,TATDN2,PITX1,CAPN7,LRPPRC,PML,HMGB2,USF2,ANAPC4,SRM,DDX47,MCCC1,CDC42SE2,S1PR2,CDIPT,SEC16A,SSR1,LIN9,PCNA,ZNF639,TRMU,PIK3R2,ETV6,PPCDC,TXLNA,FAM86C1,MYBL1,MRPL32,CCAR1,ABCC5,PBXIP1,BAZ2A,TLK1,MRPL12,EZR,LNX2,LRP5,BRCA1,PRKRA,STX16,EPB41,OPTN,SEPT1,SOCS4,QRSL1,PIEZO1,OSGEPL1,GLCCI1,NUDT11,NAA60,GEMIN7,SEPHS2,LZTR1,RACGAP1,PPP3CB,B4GALT4,RLF,RAPGEF6,SNRNP25,RB1,VASP,MED8,VMP1,PPIL2,MEA1,TIMELESS,AHDC1,ALDH18A1,TMEM8A,ABCC1,PREB,TRAPPC9,AACS,MEMO1,KRAS,RTF1,UBE4B,NFATC2IP,LY6E,ARPC1A,ZNF174,PSMC4,GOLGA4,SYNCRIP,PALB2,PRPS2,NIPA1,TIGD2,RNF114,FOXM1,MRPL39,XAB2,SUMO2,DUSP22,COMMD8,RPL11,CSDE1,MDM2,CORO1A,MINPP1,METTL9,POC5,DVL2,GM2A,PSMA8,COQ10B,CPOX,TIGD5,SLC26A6,CYP20A1,PRPF3,TXNL4A,RPSA,SRSF1,DNAJC10,SCAP,ZNF700,PLEKHG4B,TIMM17A,TOMM6,FAU,LTA4H,AP2S1,USP53,INTS2,CTDP1,MIF4GD,CDT1,ARID5A,SUMF1,GGA2,AP3S1,CSNK1A1,RMI1,TFRC,PTPN2,STARD9,IRF4,GSTK1,NDUFV1,SLC1A4,CWC27,SLC35B4,DDX31,ABCD1,RPAP3,CNTN5,SNX2,ZMYM5,CCDC34,CHCHD6,BSDC1,KPNA4,FBXO41,BIRC5,TFE3,SNAP29,CDCA7L,PKD2,ACADM,CHMP7,SAT2,GCSH,ZNF496,TMEM109,TAP1,YTHDF3,NHLRC3,IKBIP,EIF1B,ELMOD2,KIFC1,DBNDD1,CYB5RL,PARPBP,RNASEK,CDC25B,PRADC1,DNMT1,NOL12,ORAI2,USO1,AKT2,NOL8,GNG7,AURKB,MCFD2,SLC25A5,ZFAND5,MAK16,STT3A,TMED10,PSMD8,EIF2D,ITGB1,PTPN7,UQCRH,RRS1,ARRB2,RTN3,ZNF598,SVIP,DDX58,WSB2,PPIB,MUT,GMFG,HLA-E,NDUFA4,MAN2B1,METTL3,CFLAR,NDUFS4,RNF121,MEX3C,KLF16,HDAC7,DAD1,BDH1,PCYT2,GNAI2,ANKHD1,MORC3,TERF2,KCTD20,SEPT8,DCTD,PKM,TOMM40,PATL1,ADSS,SERTAD2,SERF2,ZFP92,NSF,DCK,ERGIC3,ACLY,LPCAT4,VCPIP1,YY1,PPP6R3,MAP3K5,PPP6R2,RNF14,CDK2,ZC3HAV1,SYS1,ZBTB37,URB2,EIF3D,MAGED1,KLHL18,ADPGK,SLC25A44,AP1B1,SDHA,PAIP2,PHC2,CRKL,MOAP1,TERF2IP,CYHR1,ZNF75D,SHC1,UCHL5,NAA35,TMBIM1,CCT2,CDKN2AIP,MKLN1,HMGN4,LYRM1,GALK2,CDC23,SHCBP1,AP4E1,PRDM11,VEZF1,PPP2R5A,ACYP1,STAT1,PPA2,TRIM32,RHEBL1,R3HCC1L,C1orf112,TCF3,MRI1,BRAP,AGPAT3,MYNN,SDF2L1,SPR,RAB11A,REEP5,FOXO3,MAD2L2,CCDC28A,PIP5K1C,RBM17,MAT2B,PTEN,CENPJ,TAGLN2,OSTC,CREB1,PACS2,NCOA2,SMC4,RNASEH2C,NEK7,NET1,PARP4,TBRG4,ANAPC2,RPL27A,YIF1A,SGSH,HGS,TTLL4,SLC38A7,MFAP1,CCDC69,BRWD3,ESYT2,SKA3,NPHP4,UBE2E2,HNRNPAB,PLXNC1,TMEM184B,ST13,DNAJC24,ZNF107,KIF2C,SLC29A1,AGFG1,SIRT2,FKBP2,USP48,SNRPD3,UBQLN2,CUTC,EDC3,UBLCP1,ZNF804A,RAP1A,THADA,EIF4A3,AP3S2,ATG3,DPYSL2,PPP1R12C,AKR1B1,NDUFB9,JOSD1,RP2,TTC4,TECR,ARID4A,FGFR1OP2,TIMM50,TDP1,DPM1,FOPNL,SLC16A7,WDR82,SLC25A22,STK17B,DHX15,CHAF1A,GEMIN5,COPS6,SASS6,RPS26,PSMC1,SLC12A7,TBC1D12,TM9SF4,ZNF768,UFC1,MED13L,TIA1,MEF2A,EPHX2,PITHD1,RHBDD1,NFATC3,BANF1,ZNF335,BUD31,YBX1,KNTC1,ACAD8,UBE3C,ZNF189,ALDH9A1,KDELR1,TSTA3,CIC,OXR1,PSMA1,TMEM241,SEPT7,NAP1L1,NSMF,ODF2,EXOC4,KIAA1328,NUP62,PITPNA,NAA20,PTDSS1,MZT2B,PDSS2,C7orf26,TMEM106C,IMMT,ASH1L,CHERP,WDYHV1,PLAGL2,CHKB,IRF3,TWF2,PAIP1,ANKRD28,ANKLE1,FARSA,SAR1A,SCAMP4,APOOL,PDIA6,ACSL5,TOR1AIP2,AZI2,GFER,RAD54B,DAP3,TMEM41A,ZNF317,GADD45B,AKNA,REEP4,CBX4,MIF,KIF3B,GOLPH3L,SH2D3A,CASP6,TOR3A,SRGN,DBF4,MFSD10,SAC3D1,CTNNBL1,YIF1B,CLDND1,TTC17,SLC25A1,GINS1,PAQR6,CSNK1G2,TELO2,ADAM17,HMGN1,NASP,ASPM,PPP1R21,PRKAR1B,SYMPK,TARS,SNRPA,MAPK3,HSPA1B,HLA-B,ATAD2,PLAA,ZNF330,OSBPL8,KBTBD7,PREPL |
| 6.308e-10 | -21.18 | HEDENFALK_BREAST_CANCER_BRCA1_VS_BRCA2 | MSigDB lists | HEDENFALK_BREAST_CANCER_BRCA1_VS_BRCA2 | 154 | 54 | 17377 | 2626 |
MIF,ST13,THOC1,FOXM1,HMGN3,SLC35B1,FAM136A,SDHA,STAM,PRNP,CSDE1,CDKN2C,KIF5B,FGFR3,C1GALT1,PCNA,GART,ITGB8,IARS,CRAT,SRSF4,RAB4A,MSH2,YBX1,TP53BP2,CREB1,MVP,LYPLA2,HP1BP3,GPX4,DEAF1,DPM1,CDC123,SIGMAR1,TSPAN31,E2F3,ADSL,EXOSC9,NUP155,ICAM2,CBX3,TMEM127,GNA12,SMAD2,OGT,FKBP5,SRSF3,MAPK1,SMAD4,TOB1,GCSH,PFKP,TUBB,PARD3 |
| 6.357e-10 | -21.18 | GO_REGULATION_OF_SISTER_CHROMATID_SEGREGATION | MSigDB lists | GO_REGULATION_OF_SISTER_CHROMATID_SEGREGATION | 62 | 30 | 17377 | 2626 |
ZNF207,PLK1,GORASP1,CENPF,PTTG1,CUL3,CTCF,CSNK2A1,CDC6,CDC23,CCNB1,RAB1A,BECN1,MAD2L2,FBXO5,RB1,CDC27,GOLGA2,NEK6,PTEN,NSMCE2,CDCA5,AXIN2,H2AFY,XRCC3,UBE2C,GEN1,ESPL1,TERF1,ANAPC4 |
| 6.357e-10 | -21.18 | ELVIDGE_HIF1A_TARGETS_UP | MSigDB lists | ELVIDGE_HIF1A_TARGETS_UP | 62 | 30 | 17377 | 2626 |
SRM,RPP25,HSPH1,RRP15,URB2,IDH3A,TOR3A,ABCF2,AMD1,SLC29A1,DNAJA1,GYG1,SLC35B1,SLC25A44,SCYL2,LSG1,POLR3K,PNO1,CHKA,HHEX,KPNA1,IDE,HSPA4,SEC23IP,CCDC86,RAB35,ATP6V0A2,CORO1A,RRS1,TMEM33 |
| 6.436e-10 | -21.16 | GO_REGULATION_OF_MICROTUBULE_BASED_PROCESS | MSigDB lists | GO_REGULATION_OF_MICROTUBULE_BASED_PROCESS | 228 | 71 | 17377 | 2626 |
ZNF207,CHMP2A,SKA3,PDCD6IP,CYLD,XIAP,TPX2,MYH9,SIRT2,CCNB1,STMN1,BECN1,BIRC2,KIFC1,NEK6,CDC42,CDKN1B,CEP63,PLK1,PSRC1,BIRC3,TUBGCP5,EZR,AURKB,BRCA1,CHMP2B,CCNF,KIF2A,MID1IP1,CHD3,MAP4,XRCC3,CHMP4B,CHEK2,GEN1,CSNK1D,TUBB,KIF3B,MAPRE1,DCTN2,CIB1,KIF23,HAUS4,RACGAP1,RGS2,RAB11A,TUBGCP2,HAUS2,SPAG5,FBXO5,STARD9,SMC3,CENPJ,PRC1,ARHGEF2,RHOA,ASPM,NEK7,MYBL2,MEMO1,MACF1,KIF11,BORA,HAUS8,KIF18A,GOLGA2,BIRC5,WDR62,IGBP1,TERF1,ESPL1 |
| 6.482e-10 | -21.16 | GSE1460_DP_THYMOCYTE_VS_NAIVE_CD4_TCELL_CORD_BLOOD_UP | MSigDB lists | GSE1460_DP_THYMOCYTE_VS_NAIVE_CD4_TCELL_CORD_BLOOD_UP | 171 | 58 | 17377 | 2626 |
MBD1,PDCD6IP,FOXM1,C1orf112,DYNLL1,MAGED1,ENSA,TPX2,SMARCA4,SECISBP2,KIF2C,METTL3,PARK7,NPLOC4,SSR1,HNRNPA2B1,OIP5,RNF121,NAPG,PSMA6,CCNA2,CTNNBL1,PTEN,INTS7,MTMR4,ATIC,DAD1,HDAC7,KIF14,KIF13B,PPME1,PELO,KIF22,RNASEH2A,PCBP2,MSH6,NUDC,SOCS5,VOPP1,TIMP2,TACC1,LYRM1,TEX10,CRNKL1,EZR,NUP155,LRRC1,SMC2,SOX4,H2AFV,TXNL4A,PGRMC1,DHTKD1,PKD2,RBBP4,SMAD1,POLQ,SSRP1 |
| 6.518e-10 | -21.15 | PRKDC (protein kinase, DNA-activated, catalytic polypeptide) | protein interactions | 5591 | 261 | 82 | 17029 | 2761 |
CYLD,SUMO2,CHD1L,PMS2,CSNK2A1,AP1B1,CCNB1,UBE2I,BECN1,LYN,USF1,PCNA,SHC1,DDA1,NUP107,PPP6C,TRA2B,CRY2,SRSF10,CDC5L,METTL1,AKT2,VHL,CUL3,RRM2,NFATC2,BRCA1,DCLRE1C,MCM2,RFC2,CHAF1A,PPP2CA,MKNK1,PTER,H2AFX,CHEK2,H3F3A,CLN3,XRCC4,POT1,CTDP1,CIB1,DHX9,CDC73,LMNA,RPA2,EIF2S2,MEX3C,CWC27,AHSA1,XPA,EFTUD2,ZNF746,RTCB,YBX1,PPP6R1,NUP85,PHKG2,MSH6,TELO2,STAU1,KAT2A,PRKDC,SF3B6,ILF3,ANAPC2,ADRB2,SNRPA,PRDX1,XRCC5,RPA1,NUCB1,RBM25,BIRC5,DDX5,HMGB2,PPP6R2,PPP6R3,YY1,CDK2,NIPSNAP2,TERF1 |
| 6.614e-10 | -21.14 | MODULE_62 | MSigDB lists | MODULE_62 | 76 | 34 | 17377 | 2626 |
COX5B,NDUFA5,NDUFV2,TOMM20,NDUFB6,NDUFA4,COX4I1,CYCS,ATP6V1B2,SDHA,NDUFS4,ATP6V0B,NDUFV1,NDUFA2,NDUFS8,CYC1,NDUFA3,ATP6V0D1,PPA1,ATP6V1G1,ATP2C1,ATP6V0A1,NDUFA7,NDUFB1,SLC25A5,ABCF1,SDHB,ATP6V1D,COX8A,COX5A,ATP6V0C,UQCRH,NDUFS5,ATP6V0E1 |
| 6.657e-10 | -21.13 | GSE42021_CD24INT_TREG_VS_CD24INT_TCONV_THYMUS_UP | MSigDB lists | GSE42021_CD24INT_TREG_VS_CD24INT_TCONV_THYMUS_UP | 184 | 61 | 17377 | 2626 |
PPIB,CMAS,ADD1,PRKCSH,DAP,CDT1,CUTA,CERK,C5orf30,MAN2B1,MXD4,AP1B1,RGS2,TWF2,FOXO3,REEP5,TMEM179B,MAT2B,EXOSC7,TBC1D22A,MRPL34,HADHB,GLTP,SLC38A10,ABCD1,RPL19,AQR,TALDO1,CLN6,SLC35A1,ATP6V0D1,RNF5,TIMM8B,SEC61B,GUK1,HELB,PPP1R21,WIPF1,WDR81,RIT1,OGDH,ARPC1A,COMMD4,MBD3,MAPK3,NECAP2,EIF3K,GNA12,HHEX,TRIM47,OSBPL11,WAS,CSK,CDCA7L,DCAF11,CTSA,WIPI2,ATP6V0E1,CBX4,FAF1,PTOV1 |
| 6.657e-10 | -21.13 | GSE27786_CD4_TCELL_VS_ERYTHTROBLAST_UP | MSigDB lists | GSE27786_CD4_TCELL_VS_ERYTHTROBLAST_UP | 184 | 61 | 17377 | 2626 |
SEPHS2,C9orf78,MANBA,ADO,AP3M2,CDK13,SIRT2,AGFG1,POMP,RLF,PSEN1,LCLAT1,GLRX3,IFT27,TMEM161B,RGS1,NDUFS7,ABL2,LYAR,CLUAP1,TNFAIP8,PPIG,TBC1D14,PHTF1,ZCCHC2,PPCDC,SLC38A10,AQR,SGCB,PHKG2,ARID4A,TRIM14,MYO5A,DDX28,TIMP2,HMGN5,ANKRD37,PPP1R21,TUFM,BCLAF1,ABHD11,LRRC1,DNAJA1,API5,NDRG3,TTC33,APPL1,BBS12,PHF6,SOCS7,GLOD4,EIF3K,KPNA4,GOLGA4,JAK1,BRWD1,MFAP1,PARG,CEP55,RWDD4,CSNK1D |
| 6.657e-10 | -21.13 | GSE23568_CTRL_VS_ID3_TRANSDUCED_CD8_TCELL_DN | MSigDB lists | GSE23568_CTRL_VS_ID3_TRANSDUCED_CD8_TCELL_DN | 184 | 61 | 17377 | 2626 |
NDUFA5,TXN,C19orf53,MCM10,NDUFB6,POLR2K,CDT1,CUTA,CDCA3,WDTC1,CDCA8,FLOT1,KIF23,RACGAP1,ORC1,BLM,STMN1,POLR3K,DTL,SLC31A1,DNAJC8,CCNA2,NDUFA2,NVL,SRI,PRC1,MRPL34,MRPL54,KIF22,AHCY,F2R,SAP30,NXT1,POLR2L,MYBL2,RRM2,MRPS10,NUSAP1,CDC6,AURKB,BRCA1,ANLN,KRTCAP2,MCM2,KIF11,MTR,PSMB3,ASF1B,BIRC5,CDCA5,TFDP1,MRPL27,E2F1,RWDD4,RGL1,PDXK,PGAM1,CCNB2,CHPT1,RPS26,AP2S1 |
| 6.657e-10 | -21.13 | GO_CELL_CYCLE_CHECKPOINT | MSigDB lists | GO_CELL_CYCLE_CHECKPOINT | 184 | 61 | 17377 | 2626 |
ZNF207,CLSPN,CDT1,BABAM1,CENPF,CSNK2A1,TOP2B,BCL2L1,BLM,CCNB1,MAPK14,MAD2L2,FANCI,CNOT3,DTL,RFWD3,RPA2,RB1,MDM2,PCNA,CCNA2,NEK6,INTS7,CENPJ,PTPN11,MSH2,GTSE1,CDKN1B,KNTC1,CEP63,CNOT6L,ATF2,CARM1,CDC5L,PRPF19,PLK3,TGFB1,PLK1,PRKDC,BTG2,NSUN2,TAOK1,CDC6,AURKB,BRCA1,SOX4,RBM38,BIRC5,RPS27A,E2F4,TFDP1,PML,E2F1,H2AFX,CNOT6,CHEK2,TFDP2,ZNF830,CDK2,HRAS,TERF1 |
| 6.657e-10 | -21.13 | GSE29164_UNTREATED_VS_CD8_TCELL_AND_IL12_TREATED_MELANOMA_DAY7_UP | MSigDB lists | GSE29164_UNTREATED_VS_CD8_TCELL_AND_IL12_TREATED_MELANOMA_DAY7_UP | 184 | 61 | 17377 | 2626 |
NCOR2,RECQL,ATXN3,ZCCHC9,RAF1,C16orf87,TMX4,TMEM109,LAMTOR3,KLF13,MYNN,NHLRC3,DAZAP2,XPO7,STAM,HMG20A,FBXO22,CTSS,SMC3,CTNNBL1,PRDM4,RCSD1,ATP13A3,SOCS6,INTS12,BRD7,CORO1A,MOB1A,RPRD1B,IFT46,VPS13B,SPTAN1,ZNF672,HMGN5,FOXK1,FAM49B,NOA1,NUDT4,PPP1R21,TLK1,POLG2,EML4,APPL1,FAS,PON2,TMEM41A,PPP2R5A,RBL1,QARS,RWDD4,RNF38,OGT,ZDHHC7,MRFAP1L1,MBOAT1,MAP3K5,WDR62,TMEM159,E2F2,RTN3,ZMAT3 |
| 6.711e-10 | -21.12 | mitochondrial membrane part | cellular component | GO:0044455 | 205 | 65 | 18223 | 2701 |
NDUFA5,COX15,NDUFV2,COX5B,IMMT,TOMM20,NDUFS1,NDUFB6,UQCR10,TIMM21,NDUFA4,ABCB10,COX4I1,ATP5F1B,SLC25A44,ATP5PF,LYN,SDHA,PARK7,NDUFS7,NDUFS4,NDUFV1,NDUFA2,NDUFB4,TIMM23,BDH1,MICU2,NDUFB9,NDUFS8,CYC1,APOOL,NDUFA3,TIMM50,BAK1,PPIF,ATP5IF1,COA3,COQ8A,NOA1,DMAC2,NDUFA7,ATP5MF,NDUFB1,RHOT1,TOMM40,FOXRED1,RHOT2,CHCHD6,MPC1,MFN2,ANKZF1,SDHB,CHCHD3,ATP5MC3,TIMM29,TOMM6,TIMM17A,NDUFA11,COX7A2L,COX8A,COX5A,SLC25A19,UQCRH,ATP5F1A,NDUFS5 |
| 6.754e-10 | -21.12 | GNF2_HAT1 | MSigDB lists | GNF2_HAT1 | 49 | 26 | 17377 | 2626 |
SUZ12,METTL5,CENPF,RRM1,SLBP,NUSAP1,MCM2,DHX15,SRSF1,RPA1,CBX3,CHCHD3,PA2G4,SMC3,HSPB11,RBMX,MCM5,U2SURP,SRI,HMGB2,ANP32E,NUP153,SRSF3,PTGES3,SNRPG,SMC4 |
| 6.834e-10 | -21.10 | MILI_PSEUDOPODIA_CHEMOTAXIS_DN | MSigDB lists | MILI_PSEUDOPODIA_CHEMOTAXIS_DN | 423 | 112 | 17377 | 2626 |
USP7,TMED7,PIGM,TRIM41,ABCA3,GGNBP2,ABCC10,SLC2A1,MOGS,TMEM109,PLAGL2,SLC29A1,NHLRC3,UBE2I,MAPK14,SLC20A1,APP,BCAP31,PRNP,APLP2,PSMD1,AHCTF1,ZKSCAN1,IL6ST,SRI,NOC2L,CLCN6,ZFYVE27,RPF2,RPAP1,RPN2,TAP2,PDIA6,ABCC5,ARHGAP17,ATP13A1,TIMP2,RBX1,PPT1,MAP4K4,RNPS1,ESYT1,DIDO1,EDEM2,RAB5B,KRIT1,BRMS1,ATP1A1,SEC61A1,DDOST,STT3A,NAGLU,SEL1L,ITGB1,OGT,H3F3A,CHPF2,USP53,TMEM33,CDS2,LIME1,PHB2,TRMT6,LETMD1,GMCL1,MAN2B1,THRAP3,MYO9B,SLC12A9,MYL6B,POFUT1,MFSD10,CNOT3,WWP2,CHKA,SPPL2A,GNS,RPN1,SLC1A4,PPIL2,RRBP1,SLC38A10,PIK3IP1,FAM171A1,ABCC1,SIGMAR1,TYW1,ILF3,RPS10,RPS24,BCLAF1,ADRB2,SYVN1,LY6E,MPG,KLF6,MATR3,NEU1,AKAP1,PTPRF,PLD3,SLC19A1,LTBP4,TWSG1,ACLY,GLG1,SLC16A1,PSAP,PPP6R3,ZMIZ1,SNX14,ADNP2 |
| 6.963e-10 | -21.09 | GO_PEPTIDYL_AMINO_ACID_MODIFICATION | MSigDB lists | GO_PEPTIDYL_AMINO_ACID_MODIFICATION | 796 | 184 | 17377 | 2626 |
FGFR1OP,NUP188,CXXC1,DNAJC24,SIRT2,TAF6L,FKBP2,CCNB1,UBE2I,MAPK14,PARK7,ASPHD2,CDK5,TET3,ABL2,PCNA,NUP210,NEK6,TTC9C,NUP153,TAF5L,MAST2,SENP1,ARID4A,FGFR1OP2,SEH1L,CARM1,CDC37,PLK1,SP3,DPM1,AKT2,EHMT1,WDR82,TOPORS,AURKB,BRCA1,IL12RB1,USP22,MCFD2,DOT1L,MKNK1,STT3A,OGT,BAZ1B,CAB39,ST3GAL2,CHEK2,NAA60,AAAS,PPIB,NSMCE4A,CLSPN,DHPS,PRKAA1,TOP2B,RAB6A,EZH1,SUPT7L,NUP205,FKBP1A,RPN1,SMC3,DAD1,HDAC7,PPIL2,ZNF335,TPST1,CTR9,BCL2,NUP85,CSNK1G3,MORC3,EIF5A,MAPKAPK3,LDB1,RTF1,NFATC2IP,SYVN1,VKORC1,KDM3A,MAP2K2,NMT2,MASTL,MBIP,GALNT2,CSK,CSNK1G1,SETD3,PIAS2,ZDHHC7,PRMT7,NUP62,RUVBL2,NAA20,CDK2,CDKN2A,EGLN1,ASH1L,SUMO2,PRKACA,LYN,MEAF6,PHC2,SAP130,MDM2,SP100,BRPF3,MTA1,PIN1,NUP107,RPN2,FAM76B,LMAN1,ATF2,F2R,ABI1,PPIF,KAT7,PPIE,ELP4,KIAA1586,NUP155,MBD3,TRIM28,FKBP3,JAK1,DDOST,CLK3,NSMCE2,HIPK2,STK38,CAMKMT,FKBP5,NCOA1,BEND3,XRCC4,MAPK1,CBX4,CSNK1D,PDF,RAE1,MECP2,EYA1,SCYL1,NUP54,CDCA8,TMX3,FAM76A,SMC6,JMJD6,BLM,WDR5,CSNK1A1,IRF4,FGFR3,SUV39H2,CWC27,PPIG,PRDM4,FUT8,NAA50,OSTC,NCOA2,PDPK1,CSNK1G2,KAT2A,PRKDC,RANGAP1,PPWD1,PRMT2,MEN1,MARK2,MAPK3,RPA1,NEK1,GOLGA7,MAGT1,TTLL4,BIRC5,PRDX3,PML,TAF12,HIPK3 |
| 6.984e-10 | -21.08 | colon | COSMIC cancer mutations | colon | 16934 | 2561 | 17385 | 2587 |
HECA,ZBTB10,ABCC10,HEXB,TGOLN2,CCNL2,FBXO22,EEF2K,THAP4,RAD23B,ATP13A3,DNM2,ZNRD1,FTSJ3,USP34,CCDC57,ERCC1,NRAS,EHMT1,KIF15,HNRNPF,WDHD1,MIER2,DIDO1,MCM2,RAB22A,SMAD2,MID1IP1,RPS27A,MYO18A,OGT,MPV17,COX5A,SMAD1,ZNF75A,ANXA11,SLC25A33,ZNF720,SEC61G,GGA1,MUM1,CCZ1,TRIO,CUTA,RAB23,KCTD17,HAUS4,EIF2AK4,APH1B,PARN,CDC73,MYL6B,ATG4A,TMEM179B,ERV3-1,PDXP,SMC3,C4orf3,GEMIN4,MVP,NUP85,PPP6R1,PABPC1,NSUN4,PPA1,IFRD1,AGGF1,FOXK1,RBM42,GTPBP4,MAP7D1,MRPL16,ELK1,EIF4H,RDH11,MAGED2,KPNA1,ETS2,TYW5,WIPI2,RUFY3,PDLIM5,ACSF2,EXOC3,RHOG,STARD7,C5orf30,VTI1A,INO80E,SLC35B2,LCLAT1,RCOR3,CPNE3,KIAA1147,RBM23,ZNF420,AHCTF1,TBC1D22A,TBC1D14,GMEB1,NSFL1C,SEPT11,GPD1L,ZC3H3,ARL5A,PDCL3,SNX8,ERMP1,EID1,IDH3A,POLR2D,HTATIP2,MEF2D,TMEM147,GSTCD,TANC1,MAT2A,VPS26B,CORO1C,NSMCE2,CAMKMT,PPP5C,PITRM1,TUBB,COMMD10,ZNF445,SRSF6,HABP4,CCM2,FLOT1,BTN3A1,ATG2B,ABHD14B,PPP1R3B,GOLM1,ZBTB45,HUWE1,ZNF260,NAA50,ANXA5,LTN1,KANSL2,UBE3B,NAP1L4,ZNF710,ST8SIA2,RPL22L1,MED22,SPTAN1,STAU1,DDX24,TCTEX1D2,TACC1,MRS2,LDHA,HEBP2,LLPH,RAB3IP,TTC33,PICALM,SH3BP5,SLC19A1,ACOX1,FAM3C,AEN,PARP10,YWHAH,THAP5,GPATCH4,FAM129A,TRIM11,YTHDC2,SNX15,RBM8A,ENSA,NENF,SND1,RUFY1,TRIM65,ZER1,PRNP,KRR1,RAB8A,NUP210,NT5DC1,NOC2L,EIF5,TACC3,RYBP,VPS13B,PTPN18,MIOS,SNRPB,MBLAC2,CDC6,UTP3,PBRM1,ODC1,USP21,TRAM2,FBXO28,BCL7C,ARRDC1,ADAM9,DVL1,NUMB,ZNF564,FUBP1,C1orf74,CTU2,PARP12,ZCCHC9,CENPF,LAMTOR3,CHCHD2,NCKAP1,LYRM2,RSAD1,TNS3,SUB1,RINL,SSBP3,KIF13B,MBD2,XPA,AHCY,RBM3,GLE1,MRPL48,LRSAM1,HDHD2,NTPCR,NSDHL,AMD1,CAMSAP1,ZNF761,METTL22,ICAM2,STYXL1,APPL1,BBS12,ANKRD46,RXRB,SDHB,PCM1,GALNT2,TMEM168,NLRC5,RUVBL2,MYO9A,BTBD10,CCNB2,USP7,GLT8D1,RPLP2,SUCLG1,ARID2,TMX4,SLC2A1,ATP6V1B2,PCBP1,LYN,BCAP31,VAV1,TMEM69,MRPL50,PSMA6,ZNF473,ZNF302,BRPF3,TARDBP,BCAP29,CTDSP2,PRPF19,PPIF,KDM3B,MND1,CLCN3,BIRC3,RAB7A,ANKRD33B,PPIE,CHMP2B,VDAC1,EIF3H,TMEM201,GLOD4,IDE,DHX16,UHRF2,XRCC3,CHMP4B,PARD3,BCL2L12,MCM10,C19orf53,KLHL21,PDAP1,CDCA8,TMX3,GTF3A,ARF1,SLC12A9,TUBGCP2,DNAJB9,HOMER1,WBP1L,POLR1B,RNF5,RBM15B,PPAN,RHOA,RPRD1A,BTAF1,TOP3A,ARHGEF12,PCGF1,DDX23,RAB18,CACNB1,TRIM26,PDCD6,ATP6V1D,L3MBTL3,FAM110A,NEIL3,CTBS,BBX,IMPDH1,TAF12,NR2F2,PGAM1,HIPK3,IFI16,TXN,NUP188,H2AFZ,PNISR,TMEM203,PRKCSH,USP39,UBE2I,PARK7,SLC25A37,ASPHD2,ZNF428,RAB4A,TRA2B,SUCLG2,CISD2,TAF5L,SMARCE1,ZNF800,CDC5L,ZNF524,SGCE,OSBP2,NSUN2,USP22,CLNS1A,EIF3A,ZMYM3,DOT1L,IWS1,ANKRD10,WAS,KIF18B,TPP2,C1orf109,ZMAT3,B4GALT2,PRPF38B,RECQL,C9orf78,EWSR1,GADD45G,RRM1,ACAP1,B4GALT1,CYCS,FAM136A,SUPT7L,TMEM165,CNOT3,NPLOC4,SPAG5,WDR48,RTKN,CEP104,EXOSC7,KLHL5,LRRC8D,PPP4R1,MSH2,PIGG,FBXL7,OSTF1,MRPL40,TNRC18,SYTL3,FAM171A1,APOL1,EIF5A,GCC2,PRIM2,ELL2,RDH10,MFNG,RPS24,GORASP2,CAPZA2,ADRB2,CCT8,MTR,PHF6,PFDN5,SLCO4A1,TTC13,GOLGA2,RBMX,MED15,PIAS2,APPL2,SAMD8,CDKN2A,NUDT3,ZNF511,ATXN3,RAF1,KIAA0232,C2orf49,EPM2A,CD320,CCNA2,MTMR4,BRI3,TP53BP2,AQR,RBM12B,ILKAP,CDK12,SAP30,BRD4,DRAP1,NARF,LRRC8A,ELP4,ABHD11,PKMYT1,ASB13,SERP1,TRIM28,SUPT16H,EIF3K,CHMP4A,CBWD1,ATF6,XRCC4,ADAM23,PRPF4B,NDUFS1,DEPDC1,MECP2,SECISBP2,HMG20A,WWP2,JAKMIP1,SLC25A36,CCNK,DNAJC8,AXIN2,CITED2,JMJD4,ANKRD37,KAT2A,TMEM126B,RABIF,ADSL,PACS1,BMS1,KCNQ1,OTUD3,ARSK,MACF1,KIF11,COMMD4,KLF6,SMAP2,FADD,SH3GLB1,MYO1F,CBX3,TMEM127,INF2,PPP1R11,DUSP11,DDX5,WDR62,TAF6,ESPL1,PURA,DDB1,DEF6,IPO4,FAM83G,UBL3,NAT9,PIGM,LYRM4,GPR132,UBE2Q1,PTP4A3,BRIX1,MRPL19,ZNF696,SF3B2,PCYOX1L,CDC42,SYNM,GOT2,JAZF1,HADHB,RPF2,SLC35C2,CNNM3,CARM1,SRPK2,WDR41,LARS,ZCCHC10,CCDC138,LRBA,TMEM216,SUMF2,KMT2C,OGFR,PRPSAP1,ASF1B,RPL37,MAN2A2,EIF4ENIF1,NIP7,U2SURP,MIA2,ZNF268,VPS4A,ATP6V0E1,PPP1R2,PM20D2,XPNPEP3,RGS2,LYAR,FAM89B,POLR2I,TRAFD1,SUGP2,GBA,EIF2A,SYVN1,DAPK3,ARHGAP15,MASTL,UAP1,NFIL3,FN3KRP,YWHAZ,CTSA,TMEM14A,TOB1,TSEN15,ADNP2,TCF12,PRKAB1,MDH2,SMARCA4,ORC1,RRN3,UBXN2A,IARS,CD3EAP,KIF14,EXOSC1,CS,CLTB,DNAL4,CSTF1,POU2AF1,UBQLN4,NXT1,HPDL,PGGT1B,SELPLG,SMU1,ATXN1,GLO1,OGDH,BICD2,CADM1,EDEM2,HERPUD2,TOLLIP,FANCE,MBD3,PDHX,RPS9,ALKBH6,SURF4,DUS3L,ARNTL,ANP32E,FKBP5,TMEM101,CCDC125,ABCA1,PDCD2L,GCLM,RAE1,DCTN2,NUP54,CHIC2,PAWR,MXD4,DCUN1D4,PIP4K2A,XPR1,FERMT3,KIF5B,KLHL20,SEC24C,RRBP1,ARHGEF2,ANP32A,LDLRAD3,STAT3,MYO5A,NIPAL3,AMPD2,TXNL1,PHF20L1,DCAF6,FAM49B,TMEM39A,ATP2C1,RFFL,COG1,RCOR1,PRMT2,TFEB,LEMD2,UPF1,ELMO1,ZC3H7B,DTX4,ZMIZ1,TERF1,HRAS,CCDC93,FGFR1OP,TMED7,PIGQ,AGPAT1,CNTROB,PPP1R16B,MIS12,GSDMB,TTC9C,PDS5B,NUP153,SENP1,PGAP2,TMEM115,PLEKHM3,DCUN1D5,PLEKHF2,BRMS1,PWWP2B,TRIM47,WDR11,AXIN1,SMG9,TRIM52,LONP2,NDUFV2,PHF23,CERK,SLC4A2,EZH1,ITGB5,LMNA,MCTS1,DDX56,EIF2S2,SLC38A5,FOXN2,CARS2,PRRC2A,C16orf72,RB1CC1,ZMYND11,PGS1,MYBL2,UHRF1BP1,SRSF5,MPG,MATR3,CYB5A,NCDN,POLR2J,SETD3,TEX30,PTAR1,CNOT6,NDE1,EGLN1,ZNF207,ANKRD27,ABCA3,SARNP,IVNS1ABP,RMI2,MON1B,TMEM97,NIT2,NUF2,ZNF267,TCF19,TMEM161B,KTN1,APP,PRKD3,CLUAP1,ATP2A2,UTP18,GRSF1,DUT,ZCCHC2,ANAPC7,RNF19A,FAM76B,CLN6,TMEM9,GCC1,RNF169,ADCY7,ATP6V1G1,ENPP4,RNPS1,CDCA2,FKBP3,GPR137,DDX17,CHCHD3,PEX5,CDC16,HIPK2,MBOAT1,TICAM1,PDXK,ZBTB11,ANXA6,TMBIM4,GMCL1,UBE4A,IL21R,ETS1,WRB,ZNF92,PNO1,CAPN2,ADD3,SUV39H2,TTLL12,TPCN1,TMX1,HNRNPM,LYPLA2,MFSD12,LDHB,PPP3CA,NUDT8,POLK,JTB,EMP3,MTMR12,ZP3,PDE3B,KIF18A,CCDC6,WNT5B,MAPK6,C4orf46,LY75,SLC25A19,RGL1,PSAP,WDR76,IGBP1,FAF1,SNAPIN,COX15,THOC1,AGRN,GNPDA1,GPBP1L1,PPP1R15B,CSNK2A1,EBNA1BP2,GIT2,BIRC2,ATPAF1,DLG5,ABL2,XRCC2,ZFYVE27,MCMBP,PTPRK,CDC37,SP3,METTL1,EXOSC6,HARS,GMFB,ESYT1,ANLN,RAB5B,RHEB,DPYSL3,TBC1D17,TIMM13,CDCA4,TONSL,NRM,NAGLU,ACTB,ZNF45,TMUB1,CTCF,ASAH1,DOCK11,CRLF3,ASXL2,LRRC14,NUS1,SLC27A4,AFF1,MDFIC,MAML1,CYTH1,NQO2,UTP15,EIF2AK1,EIF4G2,ZDHHC3,MOSPD3,ITPRIPL1,CDC27,SNAP23,TBPL1,PRMT7,KCTD7,NDUFA5,CYLD,UGP2,DYNLL1,COPE,HCFC1R1,ZADH2,GGPS1,RPAIN,RAD23A,ATP6V0B,PDK2,STRBP,DUS4L,MRPL34,PDCD2,SAP30L,CLPTM1,SLC39A9,RPL29,RPL35,BTG2,DNAJC9,FRAT2,MTMR6,NFATC2,KDM1B,ARL5B,USP36,CCDC127,MRPL2,ATP1A1,CLK3,MAFK,PSMD3,NDUFA11,CEP55,ZNF436,DNAJC17,NCOA1,SLC25A39,ZC3HC1,ZNF146,ATXN7L2,CDC40,SMAP1,GOLIM4,RRP15,DAP,GNE,SMC6,ARFIP2,NKRF,CHAC2,BZW2,WRNIP1,SS18L1,CENPM,PTGES3,CAMK2G,MLEC,ZNF202,PPWD1,FAM50B,RHOT2,NEU1,TPD52L2,GOLGA7,TWSG1,PGRMC1,GLG1,FAM126A,RPS6KC1,UBE2C,PPCS,NDUFB6,TMEM41B,ZDHHC8,PLXNA1,CCNB1,SLC20A1,COMMD6,ABHD14A,POLR3K,C14orf119,ASAP2,SNUPN,CNPY4,TFG,PLCL2,SEH1L,ATG9A,PBK,MKI67,DDX20,AMDHD2,GALNT7,SLC17A5,CCNF,FOXRED1,RBM47,PTER,WDR4,DHTKD1,TRAF5,HDAC2,PWWP2A,HSPH1,LIME1,MAPRE1,CHTF18,ADO,KIF23,SLC35B1,NOTCH2,PMF1,COPG2,JMY,FKBP1A,SLC31A1,SNX18,ATIC,CTPS1,ATP6V0A2,PIKFYVE,RNF135,LPCAT1,EEF1D,TMED2,FTL,PHF10,DDX28,ZNF84,SIGMAR1,PIP4K2C,FAM133B,RIT1,PLEC,KDM3A,SF3A2,FAS,EPRS,ZNF777,TMEM54,QARS,PPP3R1,TCOF1,NRBP1,CABLES1,DNMT3A,RWDD1,CKLF,TRIP10,SF3B1,RPS6KA1,CAST,SUZ12,RAC1,GPR89A,OLA1,SNN,GNB2,FLAD1,APLP2,KDM2A,TNPO2,CDKN1B,TALDO1,GPX4,ATP13A1,RFC3,MAPRE2,ERF,CUL3,SLBP,KIAA1586,H2AFV,POLG2,GAR1,PSMB9,DHX57,NSA2,HSPA4,MRPL55,JAK1,TBL3,SEL1L,H2AFX,KLHDC4,B4GALT3,PDCD11,ATMIN,POLQ,POU3F2,OTUD5,NCOR2,ANKRD13D,PKP4,SCAMP3,BABAM1,CDCA3,SLC25A12,BLM,TMCC3,GTF2F1,CRAT,AHSA1,PRC1,UPF2,COPS7B,SLC38A10,CNOT6L,CNPY3,UBE2M,IFT46,TMEM160,TSHZ1,ZFP64,STRIP1,DENND4C,DENND1B,WDR18,RPL8,ILF3,LRRC1,RHOT1,MARK2,TSR2,ECH1,PRDX1,PLD3,NUCB1,FBXO21,GNA12,C1orf131,PRDX3,PFDN4,HNRNPH3,STX18,TFDP1,KHSRP,ASNA1,CPEB2,SSSCA1,BYSL,VPS29,S100PBP,MIB2,IER2,PTMS,NOP2,UBN1,NF1,DCAF15,FLYWCH2,ALKBH5,MOGS,UBE2Z,TAF6L,MAPK14,BECN1,SNAPC4,RNF103,BCAT2,MBD4,C18orf32,METTL14,ZNHIT6,IMPAD1,RCSD1,PHTF1,SRI,KIF22,ZBTB22,NFU1,OGG1,TRIM14,ELOF1,COPS8,FYTTD1,TRIM8,RRM2,SOX4,ABHD5,UBTF,CXXC4,PAF1,UEVLD,SPATA2,PQBP1,IARS2,ATXN2L,GALNT10,STARD3NL,RPS15,PIGN,AGTRAP,CIB1,XPO7,SRRT,ZNF449,CAPZA1,GLTP,BCL2,KIFAP3,N4BP2,HP1BP3,VOPP1,THNSL1,ISG15,CAND1,C22orf46,GNAS,TSC1,RBM25,CDCA5,ZFP90,NANP,RBBP4,ZBTB24,SMARCD1,MBD1,WASF2,MMACHC,TOMM20,IFI27L1,GNPNAT1,MPHOSPH8,HNRNPUL2,CHD1,MEAF6,C2orf68,CCDC50,AKAP8,PARL,RPN2,CHTOP,FAM3A,F2R,SCYL3,TMEM14C,ABI1,HTRA2,MOSPD1,RLIM,FAM172A,ZNF500,PSMB7,NLN,WIPF1,BOLA1,BUD13,NDUFB1,PEF1,EIF3G,BTBD1,TAB2,CHCHD1,TULP3,WDR59,CANT1,SCARB1,GAS2,USP11,SMURF1,TSPAN5,PPP2R2D,CDS2,MAGEH1,MRPL42,EYA1,CDK2AP2,MRPS26,LETMD1,KLF13,HDDC2,RGS1,MAN1A1,FBXO5,GART,PELO,TANK,BRD7,MRPL11,SAMD4B,ZDHHC18,GTF3C6,POLR3GL,WDR81,MEN1,ZNF407,MFN2,COX8A,ZRANB2,MBD6,SRSF3,ATP6V1C1,IDH3B,TATDN1,TSC2,LACTB2,CMTM6,RBM4,ANKRD39,ZNF275,RPL23A,CDKN2C,NAPG,USF1,DNAAF2,MECR,AP1M1,UPRT,CRY2,ECD,RNF26,TIPARP,LRRC59,ANKRD9,MGAT5,RHBDD2,BAK1,ZNF559,RHOBTB3,GABPA,NUTF2,WBP1,GINS4,ARF4,KRIT1,BOLA3,AHNAK,RAD18,PDRG1,RNASEL,CHPF2,OAZ1,SMNDC1,PDCD4,NXT2,HIVEP3,KIAA0100,CLSPN,RHOC,DHX9,PDCD7,PSMD9,HAUS2,COPB2,CD59,TFAP4,RNFT1,RIMS3,MEGF8,EFTUD2,FBXO7,MRPL21,CPSF4,PHKG2,LUC7L2,SRSF11,EIF3L,MTA2,TYW1,USP10,ITM2A,SSR2,BCLAF1,MTX1,SFXN5,FNTA,PDLIM1,TXNDC16,TMEM159,ZNF830,MRPL3,ALS2,TRIM41,KARS,NQO1,POC1A,PTTG1,ANK3,TPX2,TBC1D13,DAZAP2,STMN1,GLRX3,C19orf48,CBWD5,REPS1,ABHD16A,FBXL6,SH3BP1,MTA1,UBA5,CLCN6,INTS12,C8orf59,RPRD1B,CGGBP1,CPNE1,SEC61B,POLR2L,FAM118B,GOPC,CRNKL1,E2F3,CIRBP,RPL38,PFKFB3,GORAB,RAB1A,GIGYF1,TMEM184C,PPP2CA,KIF2A,CCDC14,LSM6,RNF38,DMWD,SNRPG,CENPBD1,USP13,MZT1,ZFP91,TRMT6,IP6K2,WDR5,SLC25A43,PMVK,IFT27,RRP36,NEIL2,SRXN1,RPA2,PSMD2,CLIC4,PDCD10,ITGB8,CBWD2,COQ4,ARF5,ARHGEF1,FBXL19,GTF2H2,TTPAL,UTP20,MAGT1,GPS2,DBI,MRFAP1L1,SSNA1,CD81,TMEM131,WDR13,FANCI,PAPOLA,CREM,FANCL,TET3,GLIS2,IL6ST,INTS1,POP7,SLC44A1,MTPN,ASB6,PLK1,RPP25,SEPT9,CELSR2,RBX1,APH1A,RAD51AP1,ZBED5,CKAP2L,PSMG1,UBE2V1,IL12RB1,EAF2,KRTCAP2,LUC7L,LSG1,NECAP2,C1orf122,TRIM4,ALG3,AGPAT2,CHD3,ZNF367,E2F4,PRPF4,KPNA2,BEND6,CLN3,DNAJC30,FAM208A,NGLY1,POT1,MYL12B,CCDC137,RMND5A,HJURP,PHB2,FAM53C,DNAJB2,NKD2,SDC2,KLC1,CDK13,ADCK5,COX4I1,RAB6A,DNAJB1,ARID1B,C1GALT1,MLX,UBE2Q2,CCP110,ZNF746,ARL6IP1,CTR9,NIPSNAP1,ABHD2,DCAF8,ACSL3,LDB1,MAP4K3,ARMC8,RBM38,IRF5,NMT2,RPL36,HAUS8,MBIP,ORMDL2,COX7A2L,ZDHHC7,FAM122A,SIL1,DTD1,UNC13C,BCCIP,SART1,TRAF7,NDUFAF2,TOR1AIP1,ZNF416,LAGE3,TM9SF3,ZFYVE21,RRAGC,ZNF121,OIP5,NRF1,WDR44,PIN1,PPME1,EFCAB11,RPAP1,CABLES2,TOP1MT,LMAN1,AHCYL1,STRAP,SPSB3,ZNF583,SNX25,ARHGAP17,POLR2G,ZNF780B,KIAA0040,PPT1,NUP155,DCLRE1C,MRPS14,RHBDF2,SUGP1,RBL1,FASTK,UBXN2B,STK38,AP1S1,SPRYD4,SLC22A23,H3F3A,CHID1,SMAD4,RAD51D,SLC30A9,NADSYN1,UNK,CMAS,HMGN3,NCAPG,SCYL2,FZD6,HERC3,GTPBP3,CTSS,ORC3,RNLS,YTHDC1,ACP2,CSRP1,HMGN5,METTL5,ABCF2,TUFM,RANGAP1,PNPLA8,HAGH,API5,ZFR,SEC23IP,E2F1,USP20,TMEM219,RBPJ,MAX,PDCD6IP,LUZP1,GXYLT1,ADAM10,CXXC1,TSC22D3,AP3M2,CUL1,GYG1,NANS,OAT,MYEF2,ANKRD26,PA2G4,NOL11,FIZ1,ZNF200,MARCH2,SLC26A2,SRP72,KLF10,LACTB,RFC2,CBFB,RAB2B,PRIM1,MAP3K4,HHEX,RPS14,LUC7L3,MAP4,MRPL27,BTF3,PTPDC1,CCDC59,NMD3,PTOV1,COX5B,DNAJC5,SCOC,DHPS,POLR2K,ANKH,VAV2,C16orf87,PRKAA1,GSPT2,DLGAP4,TATDN3,PXMP2,PRPF39,PSEN1,ZNF79,PDXDC1,VPS25,NDUFS7,YY1AP1,C12orf10,FAM192A,RPN1,LHX8,ARPC5,ZNRF2,DAPK1,TPST1,PIK3IP1,CYC1,SOCS5,FDFT1,PIGT,WDR1,EMB,ZNF574,C1orf35,EXOSC9,ARID1A,PTTG1IP,C9orf40,FXR1,GOSR1,MAP2K2,TWISTNB,AKAP1,XRCC5,HMGN2,PI4K2A,SEC31A,CAT,DERL1,HSPBP1,MTHFD2,CEBPG,ARAP1,FAM83D,USP32,CABIN1,SMPD4,GPI,CYTIP,TP53RK,REPS2,RAB11B,UROD,SLC39A13,POMP,BCL2L1,NUDT19,DECR1,RALB,SIAH1,LPIN2,ADCY9,SOCS6,MRPS27,TTC3,RNASEH2A,CFL1,ANKLE2,CDC123,OAF,VDAC2,EDF1,ERC1,EML4,AMZ2,ANKZF1,ZNF282,RAD51C,DSN1,DDOST,HINT1,DGCR8,SAFB,HAGHL,LMBR1,RWDD4,FTSJ1,NCLN,BEND3,EYA2,DYNC1LI2,B4GALT5,SLC41A1,MANBA,TKT,FAM76A,CBLL1,ARGLU1,LANCL1,POFUT1,FAM8A1,HEATR5B,HLA-A,EBP,RFWD3,NDUFA2,FUT8,FJX1,BTF3L4,PTPN11,MRPL54,FEM1B,RPL19,CNN2,NDUFA3,MTX2,MSH6,PDLIM2,LONRF3,RFXANK,FBXO9,GUF1,RPL32,ZHX1,OAZ2,NDUFS5,WDR91,HIGD2A,ZBED3,RORB,POLA2,ZNF76,MTX3,COPA,UQCR10,HMGXB3,PHRF1,ABCB10,COMMD5,MAP1LC3B,DST,SIVA1,RAB35,GPATCH1,TCEA1,DRAM2,DEAF1,TRAPPC13,SNRNP200,NCK1,LAP3,VHL,SREK1,ARHGDIB,PITPNB,HSPB11,BRWD1,PPM1G,SH3GLB2,CRCP,BAZ1B,CAB39,ACBD4,STK11,CLU,CHEK2,ZSWIM3,TSTD2,MRPL13,CHPT1,DCAF5,CAPN1,UBE2D3,NSMCE4A,PPP1R12A,ZCCHC8,GORASP1,UBXN1,NACA,C19orf25,PCSK7,EPN1,RPL15,THRAP3,TTF1,QSOX2,PRPF18,NUP205,CHKA,DTL,MED10,ZRANB1,MCPH1,SLC12A2,ATP6V0D1,CSNK1G3,CREG1,NUDT4,RPL6,VKORC1,SLTM,EVC2,KLHL15,SIAH2,SLC16A1,EHD4,SNRNP70,C11orf1,APOL2,N4BP2L2,SNX27,CHMP2A,CORO7,FEZ2,UCK2,PMS2,UCK1,CLCC1,EXT2,MXD1,USP5,HNRNPA2B1,SAP130,NVL,PPP6C,CYB5R1,ZNF770,EBAG9,RNF25,PCGF6,METTL2A,FAM72B,PON2,HNRNPR,STAT6,HPS5,MAPK1,BRD9,TMEM33,NAT14,DNAJC2,TRIP12,SHPRH,SCYL1,VPS45,MYO9B,GFM2,SPPL2A,FASTKD3,FGFR3,MZT2A,PPIG,ZDHHC13,TMEM99,H2AFY,ATG13,NDUFS8,ERI3,FBL,FRMD8,SLC35A1,MICAL3,TGFB1,B3GALT6,ELOVL5,HEMK1,TIMMDC1,HELB,PSPC1,MIER1,SCFD2,NDRG3,ARL17A,CDK11A,MTMR3,MEGF9,ACAT1,CENPT,PLOD3,RAB3IL1,ZSWIM6,RAB14,ADD1,MRPS15,KDM4A,XIAP,DHX8,GLUD1,ANKRD23,PABPC4,CALM2,CDK5,PSMD1,NEK6,NSRP1,RABGAP1L,SRSF4,FNIP2,KCNAB2,PCBP2,MLST8,PLK3,ZNF672,HSDL1,MRPL43,TOPORS,MCL1,SMC2,PPFIA3,ICMT,SLC50A1,STOML2,LIMK1,ZNF689,PRDX5,ATE1,MLYCD,ATP6V0C,ST3GAL2,FBXL3,TFDP2,E2F2,PFKP,AAAS,DDX42,SSRP1,MRPL9,MRPS2,STRN4,TOP2B,ZNRF3,TMED3,DDRGK1,RAVER2,GNS,INTS7,INPP5A,MCM5,PHF14,ZNF326,UBE2QL1,NAGPA,TIMM8B,ETV3,TSPYL4,TSPAN31,DHX29,TEX10,MAN1B1,RPS10,CBFA2T2,ABCF1,RHOB,LRRC14B,DTWD1,PTPRF,SCARB2,OSBPL11,CCDC86,DUSP3,SLAIN1,MDH1,HEXA,RNF139,SNX14,ZNF296,TRERF1,UBR2,CHD1L,ACTR3,WDTC1,MYH9,CREBL2,NIPA2,PRKACA,SAFB2,ANKIB1,STAM,ARL6IP6,RAB21,SP100,ZKSCAN1,DDA1,NUP107,ANKRD13C,MAVS,CEP63,TMEM136,RBM15,ATF2,DCTN1,SHOC2,PSRC1,MAP4K4,WBP2,ATP6V0A1,NUSAP1,NDUFA7,DNAJA1,TAZ,C19orf54,TAF2,SEC61A1,WDR7,RPLP1,CBLN2,RBMS1,FUS,GEN1,LRP8,COIL,LRCH1,GALK1,ZNF786,RPS2,SESTD1,TRAK1,JMJD6,SIKE1,AKT1S1,KRI1,FBXO3,ERH,GATC,NDUFB4,PPP1R8,PRDM4,GTSE1,GEMIN6,DCP1A,SGCB,S100A6,IMPA2,NUDC,PDPK1,TK1,GUK1,TNFAIP3,GALC,ZNF512,KIAA0930,MRPS10,DDX39A,RPA1,ZNF862,ZNF180,KEAP1,POLE,TATDN2,PITX1,CAPN7,LRPPRC,PML,HMGB2,USF2,ANAPC4,SRM,DDX47,MCCC1,CDC42SE2,S1PR2,CDIPT,SEC16A,SSR1,LIN9,PCNA,ZNF639,TRMU,PIK3R2,ETV6,PPCDC,TXLNA,FAM86C1,MYBL1,MRPL32,CCAR1,ABCC5,PBXIP1,BAZ2A,TLK1,MRPL12,EZR,LNX2,LRP5,BRCA1,PRKRA,STX16,EPB41,OPTN,SEPT1,SOCS4,QRSL1,PIEZO1,OSGEPL1,GLCCI1,NUDT11,NAA60,GEMIN7,SEPHS2,LZTR1,RACGAP1,PPP3CB,B4GALT4,RLF,RAPGEF6,SNRNP25,RB1,VASP,MED8,VMP1,PPIL2,MEA1,TIMELESS,AHDC1,ALDH18A1,TMEM8A,ABCC1,PREB,TRAPPC9,AACS,MEMO1,KRAS,RTF1,UBE4B,NFATC2IP,LY6E,ARPC1A,ZNF174,PSMC4,GOLGA4,SYNCRIP,PALB2,PRPS2,NIPA1,TIGD2,RNF114,FOXM1,MRPL39,XAB2,SUMO2,DUSP22,COMMD8,RPL11,CSDE1,MDM2,CORO1A,MINPP1,METTL9,POC5,DVL2,GM2A,PSMA8,COQ10B,CPOX,TIGD5,SLC26A6,CYP20A1,PRPF3,TXNL4A,RPSA,SRSF1,DNAJC10,SCAP,ZNF700,PLEKHG4B,TIMM17A,TOMM6,FAU,LTA4H,AP2S1,USP53,INTS2,CTDP1,MIF4GD,CDT1,ARID5A,SUMF1,GGA2,AP3S1,CSNK1A1,RMI1,TFRC,PTPN2,STARD9,IRF4,GSTK1,NDUFV1,SLC1A4,CWC27,SLC35B4,DDX31,ABCD1,RPAP3,CNTN5,SNX2,ZMYM5,CCDC34,CHCHD6,BSDC1,KPNA4,FBXO41,BIRC5,TFE3,SNAP29,CDCA7L,PKD2,ACADM,CHMP7,SAT2,GCSH,ZNF496,TMEM109,TAP1,YTHDF3,NHLRC3,IKBIP,EIF1B,ELMOD2,KIFC1,DBNDD1,CYB5RL,PARPBP,RNASEK,CDC25B,PRADC1,DNMT1,NOL12,ORAI2,USO1,AKT2,NOL8,GNG7,AURKB,MCFD2,SLC25A5,ZFAND5,MAK16,STT3A,TMED10,PSMD8,EIF2D,ITGB1,PTPN7,UQCRH,RRS1,ARRB2,RTN3,ZNF598,SVIP,DDX58,WSB2,PPIB,MUT,GMFG,HLA-E,NDUFA4,MAN2B1,METTL3,CFLAR,NDUFS4,RNF121,MEX3C,KLF16,HDAC7,DAD1,BDH1,PCYT2,GNAI2,ANKHD1,MORC3,TERF2,KCTD20,SEPT8,DCTD,PKM,TOMM40,PATL1,ADSS,SERTAD2,SERF2,ZFP92,NSF,DCK,ERGIC3,ACLY,LPCAT4,VCPIP1,YY1,PPP6R3,MAP3K5,PPP6R2,RNF14,CDK2,ZC3HAV1,SYS1,ZBTB37,URB2,EIF3D,MAGED1,KLHL18,ADPGK,SLC25A44,AP1B1,SDHA,PAIP2,PHC2,CRKL,MOAP1,TERF2IP,CYHR1,ZNF75D,SHC1,UCHL5,NAA35,TMBIM1,CCT2,CDKN2AIP,MKLN1,HMGN4,LYRM1,GALK2,CDC23,SHCBP1,AP4E1,PRDM11,VEZF1,PPP2R5A,ACYP1,STAT1,PPA2,TRIM32,RHEBL1,R3HCC1L,C1orf112,TCF3,MRI1,BRAP,AGPAT3,MYNN,SDF2L1,SPR,RAB11A,REEP5,FOXO3,MAD2L2,CCDC28A,PIP5K1C,RBM17,MAT2B,PTEN,CENPJ,TAGLN2,OSTC,CREB1,PACS2,NCOA2,SMC4,RNASEH2C,NEK7,NET1,PARP4,TBRG4,ANAPC2,RPL27A,YIF1A,SGSH,HGS,TTLL4,SLC38A7,MFAP1,CCDC69,BRWD3,ESYT2,SKA3,NPHP4,UBE2E2,HNRNPAB,PLXNC1,TMEM184B,ST13,DNAJC24,ZNF107,KIF2C,SLC29A1,AGFG1,SIRT2,FKBP2,USP48,SNRPD3,UBQLN2,CUTC,EDC3,UBLCP1,ZNF804A,RAP1A,THADA,EIF4A3,AP3S2,ATG3,DPYSL2,PPP1R12C,AKR1B1,NDUFB9,JOSD1,RP2,TTC4,TECR,ARID4A,FGFR1OP2,TIMM50,TDP1,DPM1,FOPNL,SLC16A7,WDR82,SLC25A22,STK17B,DHX15,CHAF1A,GEMIN5,COPS6,SASS6,RPS26,PSMC1,SLC12A7,TBC1D12,TM9SF4,ZNF768,UFC1,MED13L,TIA1,MEF2A,EPHX2,PITHD1,RHBDD1,NFATC3,BANF1,ZNF335,BUD31,YBX1,KNTC1,ACAD8,UBE3C,ZNF189,ALDH9A1,KDELR1,TSTA3,CIC,OXR1,PSMA1,TMEM241,SEPT7,NAP1L1,NSMF,ODF2,EXOC4,KIAA1328,NUP62,PITPNA,NAA20,PTDSS1,MZT2B,PDSS2,C7orf26,TMEM106C,IMMT,ASH1L,CHERP,WDYHV1,PLAGL2,CHKB,IRF3,TWF2,PAIP1,ANKRD28,ANKLE1,FARSA,SAR1A,SCAMP4,APOOL,PDIA6,ACSL5,TOR1AIP2,AZI2,GFER,RAD54B,DAP3,TMEM41A,ZNF317,GADD45B,AKNA,REEP4,CBX4,MIF,KIF3B,GOLPH3L,SH2D3A,CASP6,TOR3A,SRGN,DBF4,MFSD10,SAC3D1,CTNNBL1,YIF1B,CLDND1,TTC17,SLC25A1,GINS1,PAQR6,CSNK1G2,TELO2,ADAM17,HMGN1,NASP,ASPM,PPP1R21,PRKAR1B,SYMPK,TARS,SNRPA,MAPK3,HSPA1B,HLA-B,ATAD2,PLAA,ZNF330,OSBPL8,KBTBD7,PREPL |
| 7.015e-10 | -21.08 | RAB7A (RAB7A, member RAS oncogene family) | protein interactions | 7879 | 173 | 61 | 17029 | 2761 |
RHOG,CHMP2A,COX15,NDUFV2,IMMT,TMUB1,NDUFS1,RAB11B,PHB2,FLOT1,RAB6A,ATP6V1B2,EIF1B,RAB11A,GNB2,KTN1,TFRC,XPR1,RPA2,RAB8A,RAP1A,ATP2A2,NDUFB4,UCHL5,RAB4A,MECR,GTSE1,ABCD1,RPN2,ATF2,ATP6V0D1,CFL1,ATP6V1G1,MLEC,LAP3,ERLIN1,VDAC2,TMEM216,ATP6V0A1,UBE2V1,NDUFA7,NUTF2,VDAC1,CHMP2B,RAB1A,RAB5B,EIF4G2,CHCHD6,RAB22A,RHEB,RPA1,STOML2,SDHB,CHCHD3,CORO1C,LRPPRC,CHMP4B,PIEZO1,FUS,OAZ1,VPS29 |
| 7.044e-10 | -21.07 | CHEK1 (checkpoint kinase 1) | protein interactions | 1111 | 153 | 56 | 17029 | 2761 |
USP7,NAT9,PIGM,CLSPN,XIAP,CUL1,CSNK2A1,SMARCA4,RACGAP1,BCL2L1,BLM,APP,CDC73,RAD23A,DTL,VAV1,RB1,ZBTB21,PCNA,PTEN,KIF13B,MSH2,TIMELESS,FEM1B,CDC25B,TCEA1,MCPH1,DNMT1,MSH6,CDC5L,BRD4,AATF,VHL,PRKDC,TLK1,RPS10,TOP3A,CDC6,NFATC2,BRCA1,ARID1A,MEN1,FANCE,TARS,GIGYF1,XRCC5,E2F4,MED15,E2F1,IMPDH1,FUS,CHEK2,USP11,MAPK1,SMAD4,DDB1 |
| 7.159e-10 | -21.06 | GSE27786_BCELL_VS_CD8_TCELL_UP | MSigDB lists | GSE27786_BCELL_VS_CD8_TCELL_UP | 193 | 63 | 17377 | 2626 |
RAB14,CORO7,TSC2,TMBIM4,POLR2K,ZFP91,EYA1,TOR1AIP1,GADD45G,MON1B,PMF1,CNTROB,DAZAP2,RUFY1,REEP5,TFRC,PAIP2,CDKN2C,RB1,ATP6V0B,TNS3,CLIC4,BRPF3,PPP4R1,ZNF326,ABCD1,RP2,ATP6V0D1,NUP85,TACC3,ALDH9A1,ELOF1,SLC39A9,CYFIP1,TK1,HEMK1,RPRD1A,TCTEX1D2,PRIM2,ANKRD37,EID1,VHL,RAD51AP1,ANKRD33B,PBK,PPP1R21,RDH10,PFKFB3,BICD2,LY6E,SH3GLB1,HSPA1B,POLR2J,CDC27,RAB24,MFAP1,GADD45B,ADAM9,SLC25A19,NUP62,NCOA1,PPP5C,CWC25 |
| 7.201e-10 | -21.05 | GSE27786_NKCELL_VS_MONO_MAC_UP | MSigDB lists | GSE27786_NKCELL_VS_MONO_MAC_UP | 180 | 60 | 17377 | 2626 |
MIF,OTUD5,RWDD1,RRP15,DHPS,ADAM10,HLA-E,MRPL39,ADO,UROD,TIA1,HMGN3,CSNK1A1,ASXL2,C19orf48,PARK7,PAIP2,CSDE1,NRF1,CNPY4,EI24,MSH2,TAP2,CLDND1,ABI1,HTRA2,MRPL32,NUDC,CDC5L,ENPP4,ELOVL5,ADAM17,DDX24,MIOS,KLF10,TACC1,DENND4C,PPIE,TEX10,RPS10,SSR2,MAP7D1,BCLAF1,ODC1,TRIM28,RPS9,BTBD1,CLNS1A,EIF3A,PHF6,SH3GLB1,BRD2,DUS3L,BBX,ACAT1,TCOF1,FAU,PURA,VPS29,RNF114 |
| 7.306e-10 | -21.04 | Cell cycle | KEGG pathways | hsa04110 | 124 | 48 | 7161 | 1149 |
PTTG1,GADD45G,DBF4,CUL1,ORC1,CCNB1,MAD2L2,CDKN2C,RB1,MDM2,PCNA,SMC3,CCNA2,MCM5,CDKN1B,ANAPC7,CDC25B,ORC3,TGFB1,PLK1,RBX1,PRKDC,E2F3,ANAPC2,CDC6,PKMYT1,MCM2,CDC23,SMAD2,CDC16,CDC27,RBL1,E2F4,GADD45B,TFDP1,E2F1,YWHAZ,CHEK2,TFDP2,CCNB2,CDK2,E2F2,YWHAH,SMAD4,ESPL1,CDKN2A,HDAC2,ANAPC4 |
| 7.306e-10 | -21.04 | Cell cycle | KEGG pathways | ko04110 | 124 | 48 | 7161 | 1149 |
PTTG1,GADD45G,DBF4,CUL1,ORC1,CCNB1,MAD2L2,CDKN2C,RB1,MDM2,PCNA,SMC3,CCNA2,MCM5,CDKN1B,ANAPC7,CDC25B,ORC3,TGFB1,PLK1,RBX1,PRKDC,E2F3,ANAPC2,CDC6,PKMYT1,MCM2,CDC23,SMAD2,CDC16,CDC27,RBL1,E2F4,GADD45B,TFDP1,E2F1,YWHAZ,CHEK2,TFDP2,CCNB2,CDK2,E2F2,YWHAH,SMAD4,ESPL1,CDKN2A,HDAC2,ANAPC4 |
| 7.348e-10 | -21.03 | MORF_USP5 | MSigDB lists | MORF_USP5 | 46 | 25 | 17377 | 2626 |
NUP188,AATF,WDR18,AGPAT1,STARD7,BMS1,ESYT1,MTX1,ELK1,PARN,POLR2A,MFN2,USP5,EBP,TFAP4,RPA2,PSMD2,DNAJC8,PSMD3,MEA1,TXLNA,CS,PPP1R11,NAP1L4,DDB1 |
| 7.457e-10 | -21.02 | U2AF1 (U2 small nuclear RNA auxiliary factor 1) | protein interactions | 7307 | 126 | 49 | 17029 | 2761 |
SART1,RPS2,EWSR1,CHERP,ZCCHC8,SF3B1,SUZ12,DHX9,RPL15,CUL1,JMJD6,SF3B2,DDX56,MCM5,ZNF746,AP2B1,FBL,PABPC1,FTSJ3,LUC7L2,HNRNPM,CDC5L,PRPF19,SRPK2,ZCCHC10,SF3B6,RNPS1,CUL3,RPS24,DIDO1,SRSF5,SEPT7,SF3A2,SRSF1,EPB41,CAND1,SYNCRIP,RBM25,MFAP1,SAFB,RPS14,DDX5,ZRANB2,PRPF4,PSAP,RRS1,CFAP20,SMURF1,TERF1 |
| 7.641e-10 | -20.99 | MORF_SMC1L1 | MSigDB lists | MORF_SMC1L1 | 59 | 29 | 17377 | 2626 |
CCT2,SNRNP200,H2AFZ,NASP,HNRNPAB,CHERP,RRM1,STARD7,SLBP,CTCF,SMARCA4,DDX39A,EIF4H,TRIM28,SRSF1,RAD23A,CBX3,HNRNPA2B1,PCNA,HSPB11,SYNCRIP,HNRNPR,RBMX,ACLY,MSH2,TRA2B,TARDBP,HNRNPM,MSH6 |
| 7.654e-10 | -20.99 | establishment of RNA localization | biological process | GO:0051236 | 188 | 62 | 17256 | 2622 |
RPS15,NDC1,TOMM20,NUP188,CDC40,SARNP,THOC1,SRSF6,RAE1,RBM8A,DHX9,ALKBH5,FLOT1,NUP54,AGFG1,XPO7,NUP205,HNRNPA2B1,AHCTF1,NUP210,SNUPN,EIF4A3,SRSF4,NUP107,UPF2,NUP153,GLE1,CHTOP,MVP,CPSF4,ZC3H3,NUP85,SEH1L,SRSF11,EIF5A,FYTTD1,NXT1,POLR2D,RNPS1,SLBP,NUP155,BICD2,NUTF2,SRSF5,DDX39A,SYMPK,NPIPA1,RPSA,SRSF1,IWS1,HHEX,TSC1,UPF1,LRPPRC,KHSRP,NUP62,SRSF3,RRS1,NMD3,NUP58,AAAS,NXT2 |
| 7.832e-10 | -20.97 | CEP128 (centrosomal protein 128) | protein interactions | 145508 | 275 | 85 | 17029 | 2761 |
MIB2,TRIM41,NDUFA5,FGFR1OP,NPHP4,DDX47,CYLD,COPA,LUZP1,DYNLL1,GLUD1,CNTROB,CCNB1,PRKACA,SDHA,ANKRD28,CDK5,ANKRD26,DLG5,KIF14,TXLNA,GPATCH1,AP2B1,CEP63,ECD,TP53BP2,AHCYL1,DVL2,POC5,SRP72,PLK1,CCDC138,CDC123,FOPNL,BICD2,TANC1,PEF1,ERC1,GIGYF1,NECAP2,EIF4ENIF1,CCDC14,SPATA2,CEP55,DVL1,AP2S1,CSNK1D,CEP170B,VPS45,PROSER3,SLC25A12,HAUS4,PAWR,NCKAP1,PM20D2,CSNK1A1,HAUS2,NUP205,NPLOC4,NFATC3,CCP110,TANK,NDUFS8,IFT46,TMED2,MOB4,GID8,CAMSAP1,ADSL,CIP2A,DAPK3,SH3GLB1,ECH1,POLR2A,HAUS8,XRCC5,COMMD3-BMI1,PCM1,TRIM26,ODF2,EXOC4,NDE1,YWHAH,PDLIM5,CCNB2 |
| 7.843e-10 | -20.97 | ATF2 (activating transcription factor 2) | protein interactions | 1386 | 219 | 72 | 17029 | 2761 |
RAB14,IMMT,MDH2,SLC2A1,CSNK2A1,OAT,UBE2I,MAPK14,PCBP1,GNB2,APP,BCAP31,PCNA,ATP2A2,CS,HADHB,ATF2,CFL1,PPIF,CCT2,RAB7A,VDAC2,CUL3,EDF1,VDAC1,RAB2B,ARF4,AHNAK,ATP1A1,DDOST,RAD18,TMED10,PRDX5,ITGB1,H2AFX,MAPK1,SMAD4,PPP2R2D,TUBB,FUBP1,HSPH1,PHB2,RHOC,NACA,SLC25A12,ATP5F1B,ARF1,ETS1,RAB11A,TFRC,RPN1,RB1,ANXA5,H2AFY,AHCY,TAGLN2,MYDGF,CYC1,CREB1,TMX1,LDHB,EIF5A,ERO1A,LDHA,PKM,MAPK3,CCDC6,PFDN4,CEBPG,PML,RUVBL2,YY1 |
| 7.843e-10 | -20.97 | SDHA (succinate dehydrogenase complex flavoprotein subunit A) | protein interactions | 6389 | 219 | 72 | 17029 | 2761 |
RAB14,COPA,SUCLG1,MDH2,TMEM109,TAP1,CUL1,CPNE3,FARSA,RAB21,PSMD1,EIF4A3,IMPAD1,CS,SUCLG2,CRY2,RPN2,PDIA6,TIMM50,CPNE1,CCT2,IDH3A,WBP2,CUL3,LRRC8A,NFATC2,SLC25A5,MAT2A,GLOD4,CHCHD3,ATP1A1,HSPA4,TMED10,COPS6,ARRB2,PSMC1,SSRP1,NDUFV2,PPIB,TKT,CHCHD2,PMVK,LMNA,HLA-A,PSMD2,RPN1,SMC3,NDUFV1,NDUFA2,MCM5,BANF1,ANXA5,NDUFS8,CYC1,ATP6V0D1,LDHB,LDHA,CCT8,CAND1,SDHB,HLA-B,EPRS,PRDX3,HNRNPH3,ACLY,NAXE,ACAT1,YWHAZ,MDH1,RUVBL2,PGAM1,PDSS2 |
| 8.022e-10 | -20.94 | EEF2 (eukaryotic translation elongation factor 2) | protein interactions | 1938 | 194 | 66 | 17029 | 2761 |
CYLD,TXN,RPS6KA1,CUL1,MAPK14,SDHA,RBM4,PARK7,RPL11,RAD23A,EEF2K,FARSA,MDM2,UCHL5,PPME1,CRY2,TARDBP,ATF2,CCT2,CUL3,NFATC2,BRCA1,MCM2,VDAC1,MAT2A,PPP2CA,AHNAK,FUS,COPS6,ARRB2,SMURF1,CAPN1,TUBB,UNK,RPS2,RRM1,CDK13,NOTCH2,CDC73,WWP2,NDUFV1,HUWE1,PTEN,ATIC,ZNF746,DAPK1,TAGLN2,PABPC1,MAPKAPK3,RPL6,RPS24,FBXO9,ADRB2,TOMM40,RHOT2,EIF4H,TARS,ISG15,CAND1,UPF1,DDX5,NUP62,HNRNPDL,CDK2,IPO4,CDKN2A |
| 8.273e-10 | -20.91 | chromosome segregation | biological process | GO:0007059 | 311 | 89 | 17256 | 2622 |
ZNF207,CHMP2A,NDC1,SKA3,PDCD6IP,DYNLL1,PTTG1,ACTR3,NUF2,KIF2C,CCNB1,UBE2I,BECN1,MIS12,OIP5,KIFC1,ANKLE1,AHCTF1,NEK6,ABRAXAS2,KIF14,AKAP8,NUP107,PDS5B,KIF22,TOP1MT,MCMBP,SEH1L,PLK1,PSRC1,TAOK1,CUL3,NUSAP1,SMC2,AURKB,BRCA1,CHMP2B,CDC23,SLC25A5,CENPU,KIF2A,RAD51C,CHMP4A,DSN1,KIF18B,CEP55,CHMP4B,VPS4A,RRS1,NAA60,DYNC1LI2,MAPRE1,HJURP,PHB2,PHF23,CDT1,CENPF,CDCA8,CTCF,KIF23,TOP2B,RACGAP1,PMF1,SPDL1,NCAPG,RAB11A,SPAG5,RB1,SMC3,PRC1,NAA50,CENPM,KNTC1,NUP85,SMC4,NUDC,RANGAP1,KIF11,LEMD2,KIF18A,BIRC5,CDCA5,FAM83D,NUP62,CENPT,NDE1,CHMP7,ESPL1,TERF1 |
| 8.480e-10 | -20.89 | MODULE_17 | MSigDB lists | MODULE_17 | 351 | 97 | 17377 | 2626 |
TCF12,RHOG,IMMT,PTTG1,UCK2,TPX2,CSNK2A1,SMARCA4,PTP4A3,SLC29A1,KIF2C,BCL2L1,ORC1,CCNB1,STMN1,SSR1,MBD4,SEC11A,DECR1,PCNA,CCNA2,MTA1,KIF14,MRPS27,AP1M1,DNM2,NUP153,RNASEH2A,AHCYL1,EIF5,DNMT1,PRPF19,PLK1,HMGN4,MRPL12,VDAC2,PSMB7,PSMG1,AURKB,PKMYT1,MCFD2,MCM2,CHAF1A,PRIM1,HHEX,DAP3,HSPB11,IARS2,H2AFX,CLN3,MAPRE1,UBXN1,DHX9,SLC4A2,TMED3,ITGB5,WRB,TFRC,NUP205,EBP,TFAP4,GART,PDCD10,SEC24C,ATIC,MSH2,AHCY,MRPL40,LPCAT1,UBE2M,TMX1,FDFT1,TK1,RBM42,PRKDC,ACSL3,ILF3,EMP3,BMS1,RANGAP1,TOMM40,DDX39A,ABCF1,SF3A2,ISG15,PSMC4,CBX3,SDHB,NAP1L1,MAPK6,LRPPRC,RBBP4,CDK2,IGBP1,CCNB2,MRPL3,BYSL |
| 8.485e-10 | -20.89 | GSE37416_CTRL_VS_24H_F_TULARENSIS_LVS_NEUTROPHIL_DN | MSigDB lists | GSE37416_CTRL_VS_24H_F_TULARENSIS_LVS_NEUTROPHIL_DN | 185 | 61 | 17377 | 2626 |
CCDC93,NDUFA5,PPP1R2,GPBP1L1,SEC61G,PPP1R15B,DBF4,ALKBH5,LAMTOR3,TM9SF3,ADPGK,AP3S1,CSNK1A1,MAP1LC3B,PCBP1,SCYL2,DNAJB9,CCNK,RAB21,PSMA6,EIF4A3,RNFT1,AP3S2,MEA1,JOSD1,CISD2,CLDND1,PIK3IP1,PTGES3,TFG,ATF2,LPCAT1,FGFR1OP2,RYBP,TNFAIP3,BIRC3,ELL2,ATG9A,NARF,CBFA2T2,VDAC1,ARL5B,KDM3A,SH3BP5,FNTA,TWSG1,HPS5,SAFB,NSMCE2,GADD45B,CAPN7,MAPK6,CHMP4B,GPI,RBPJ,PDXK,CDK2,NGLY1,PGAM1,IGBP1,ANXA11 |
| 8.485e-10 | -20.89 | GSE9988_LPS_VS_CTRL_TREATED_MONOCYTE_DN | MSigDB lists | GSE9988_LPS_VS_CTRL_TREATED_MONOCYTE_DN | 185 | 61 | 17377 | 2626 |
WASF2,HECA,DNAJC5,PHF23,TSC22D3,KLF13,CTCF,GTF3A,MAPK14,PCBP1,SYNRG,GIT2,MEAF6,PIP5K1C,SF3B2,PHC2,RAB8A,MLX,RALB,PPP1R8,MBD2,FBXO7,FAM89B,GLTP,ZNF226,NAP1L4,GLE1,MAP3K14,FRMD8,CTDSP2,PDLIM2,KDM3B,FYTTD1,ORAI2,FOXK1,ADSL,FRAT2,SLBP,MAP7D1,USP22,FADD,DDX23,MYO1F,TFEB,ZNF282,HHEX,FBXO21,OSBPL11,CSK,ZNF689,ARAP1,RNF38,CCDC69,ZDHHC7,NUP62,WIPI2,YY1,ARRB2,DCAF5,NRBP1,SNAPIN |
| 8.500e-10 | -20.89 | GOLDRATH_ANTIGEN_RESPONSE | MSigDB lists | GOLDRATH_ANTIGEN_RESPONSE | 327 | 92 | 17377 | 2626 |
ZNF207,UBL3,TMED7,H2AFZ,TXN,GNPDA1,TMEM97,KIF2C,CCNB1,STMN1,TCF19,LYN,POLR3K,CDKN2C,PCNA,CCNA2,SP100,CCDC50,SIVA1,KIF22,LRRC59,F2R,TMEM14C,ARL5A,TACC3,PLK1,MAPRE2,RAD51AP1,CPOX,MKI67,RRM2,NUSAP1,CDC6,AURKB,BRCA1,IL12RB1,KRTCAP2,CCNF,ANLN,H2AFV,ODC1,ASF1B,CHAF1A,PRIM1,AHNAK,GADD45B,ITGB1,H2AFX,KPNA2,MCM10,CDCA8,RRM1,CDCA3,RACGAP1,REEP5,RAB11A,HLA-A,LMNA,EBP,DTL,CAPN2,IRF4,SLC31A1,CLIC4,C4orf3,MCM5,PRC1,GTSE1,RBM3,MDFIC,CITED2,SGCB,S100A6,CYFIP1,TK1,PRIM2,ELL2,ASPM,NUDT4,EMP3,KIF11,ECH1,MYO1F,MTHFD2,BIRC5,MAPK6,NFIL3,CDCA5,DBI,HMGB2,CCNB2,PGAM1 |
| 8.555e-10 | -20.88 | PABPC1 (poly(A) binding protein cytoplasmic 1) | protein interactions | 26986 | 245 | 78 | 17029 | 2761 |
SART1,COX15,CYLD,RPLP2,GNPDA1,DYNLL1,RBM8A,CUL1,SNRPD3,BRIX1,ATP6V1B2,PCBP1,RBM4,PARK7,PAIP1,PAIP2,RPL11,PAPOLA,PRNP,CSDE1,PIN1,TARDBP,PCBP2,CARM1,SRPK2,SNRNP200,RPL35,CUL3,SREK1,PRPF3,BRCA1,MCM2,VDAC1,DHX15,RPSA,CHAF1A,PPP2CA,HNRNPR,CLK3,ATXN2L,H2AFX,COPS6,ARRB2,MIF,R3HCC1L,RAE1,AGO2,GSPT2,PCSK7,RPL15,PSMD9,WWP2,RPA2,MEX3C,RPL17,PABPC1,LUC7L2,STAU1,ZMYND11,ILF3,RPL6,USP10,RPL27A,DDX39A,SNRPA,CAND1,RPA1,UPF1,PDCD6,UAP1,POLE,SYNCRIP,CNOT6,ATP5F1A,SNRNP70,IGBP1,CD81,TOB1 |
| 8.565e-10 | -20.88 | nucleotide binding | molecular function | GO:0000166 | 2092 | 418 | 17224 | 2647 |
RAB14,ABCC10,TAP1,DHX8,GLUD1,UBE2I,EEF2K,KIFC1,CDK5,NEK6,CYB5RL,RAB4A,ATP13A3,PDS5B,DNM2,UPRT,SUCLG2,CRY2,MAST2,DNMT1,PLK3,RHOBTB3,NRAS,AKT2,PBK,KIF15,MKI67,DDX20,SMC2,AURKB,MCM2,RFC2,RAB22A,RAB2B,ARF4,MAP3K4,MKNK1,KIF18B,LIMK1,MYO18A,RNASEL,LONP2,PFKP,DDX42,DDX58,HSPH1,RECQL,CHTF18,RHOC,TRIO,GSPT2,PRKAA1,DHX9,RRM1,RAB23,CERK,KIF23,TOP2B,EIF2AK4,RTKN,DDX56,SMC3,MCM5,EFTUD2,CTPS1,MSH2,DAPK1,RTCB,PIKFYVE,GNAI2,PHKG2,UBE2QL1,CARS2,DDX28,COQ8A,MAPKAPK3,DHX29,NOA1,PGS1,TYW1,GTPBP4,PIP4K2C,SEPT8,RIT1,PKM,ABCF1,MAP2K2,CCT8,RHOB,PI4K2A,XRCC5,CAT,ADSS,EPRS,HSPBP1,NSF,CSK,CSNK1G1,DCK,QARS,ACLY,MDH1,MAP3K5,CDK2,NRBP1,ACSF2,ZC3HAV1,RHOG,KARS,ABCA3,TP53RK,RAB11B,RPS6KA1,RAF1,CHD1L,KIAA0232,RAC1,ACTR3,OLA1,TPX2,MYH9,EFL1,PRKACA,SDHA,CBWD5,FLAD1,DECR1,RAB21,PRKD3,ATP2A2,RALB,UBA5,ADCY9,CLCN6,SEPT11,TAP2,AQR,GPD1L,ARL5A,CDK12,ADCY7,CCT2,ULK3,ATP13A1,IDH3A,MAP4K4,TAOK1,POLR2D,VDAC2,PFKFB3,GALK2,PKMYT1,DNAJA1,RAB1A,MAT2A,DHX57,DDX17,KIF2A,RAD51C,HSPA4,JAK1,HINT1,RAB24,GUCY1B1,NT5C3B,HIPK2,CBWD1,PDXK,PPP5C,CSNK1D,TUBB,DYNC1LI2,RHEBL1,PRPF4B,POLQ,GALK1,ANXA6,TWNK,MECP2,IP6K2,ATP5F1B,BLM,SPR,PMVK,IFT27,RAB11A,PIP5K1C,SRXN1,ERH,GATC,CBWD2,ARF5,TTLL12,MAP3K14,UBE2M,MSH6,SMC4,LDHB,PDPK1,TK1,DDX24,GUK1,NEK7,LDHA,BMS1,RHOT1,DDX39A,GUF1,KIF11,MARK2,MYO1F,GNA12,KIF18A,POLE,TTLL4,ACOX1,MAPK6,NAXE,ASNA1,DDX5,DDX52,DDX47,UBE2E2,ST13,YTHDC2,MCCC1,CSNK2A1,UBE2Q1,UBE2Z,ABCB10,KIF2C,SIRT2,MAPK14,PAPOLA,ABL2,RAB8A,RAP1A,CDC42,EIF4A3,RAB35,TRMU,XRCC2,KIF22,RP2,EIF5,ABCC5,SRPK2,PLK1,LARS,SNRNP200,SEPT9,HARS,TLK1,CDC6,RAB5B,LSG1,STK17B,DHX15,RHEB,SEPT1,CHD3,IARS2,CRCP,BAZ1B,QRSL1,ACTB,STK11,CHEK2,DHFR2,VPS4A,ROCK1,PSMC1,SEPHS2,UBE2D3,CDK13,RAB6A,THRAP3,CHKA,UBE2Q2,MBD2,KIF13B,SLC27A4,AHCY,ACAD8,ALDH18A1,N4BP2,CSNK1G3,ABCC1,NTPCR,AACS,NQO2,ACSL3,KRAS,MAP4K3,EIF2AK1,UBE4B,SEPT7,DAPK3,BBS12,MASTL,PSMC4,GNAS,PRPS2,NLRC5,SIL1,RUVBL2,ATP5F1A,EHD4,MYO9A,MBD1,MMACHC,SUCLG1,UGP2,MRPL39,UCK2,PMS2,SMARCA4,RRAGC,UCK1,CHKB,ORC1,ATP6V1B2,LYN,TWF2,CHD1,MIEF1,FARSA,ZBTB21,PDK2,IARS,DUS4L,SAR1A,NVL,KIF14,CYB5R1,CHTOP,SCYL3,ACSL5,CLCN3,CGAS,RAB7A,KDM1B,ARL5B,MBD3,GFER,RAD54B,DAP3,ATP1A1,IDE,DUS3L,DHX16,CLK3,FASTK,STK38,XRCC3,MAPK1,ABCA1,RAD51D,NADSYN1,KIF3B,SHPRH,TOR3A,SCYL1,GNE,SMC6,ARFIP2,ARF1,MYO9B,CDK11B,CSNK1A1,RMI1,SCYL2,PIP4K2A,GFM2,WRNIP1,KIF5B,GTPBP3,FGFR3,STARD9,NDUFV1,GART,GRK2,DUS2,ABCD1,DDX31,CAMK2G,MICAL3,MYO5A,RNLS,CSNK1G2,RHOA,PRKDC,HELB,BTAF1,ATP2C1,ABCF2,TUFM,PRKAR1B,NADK2,PNPLA8,RHOT2,CDK11A,TARS,MAPK3,DDX23,HSPA1B,MFN2,RAB18,NEK1,UPF1,ATAD2,ACADM,IDH3B,RPS6KC1,UBE2C,HRAS,HIPK3,TYW1B |
| 9.054e-10 | -20.82 | GNF2_DEK | MSigDB lists | GNF2_DEK | 56 | 28 | 17377 | 2626 |
SRP72,HNRNPAB,ZCCHC8,SUZ12,SUMO2,SLBP,DHX15,EIF3A,SRSF1,RPA1,PAPOLA,CBX3,HSPB11,HNRNPR,MCM5,RBMX,DUT,U2SURP,SRI,TRA2B,HMGB2,NUP153,ANP32E,TARDBP,PTGES3,SRSF3,HNRNPM,SMC4 |
| 9.059e-10 | -20.82 | GSE28726_NAIVE_CD4_TCELL_VS_NAIVE_VA24NEG_NKTCELL_UP | MSigDB lists | GSE28726_NAIVE_CD4_TCELL_VS_NAIVE_VA24NEG_NKTCELL_UP | 194 | 63 | 17377 | 2626 |
MIF,TMEM106C,SRM,KIF3B,GALK1,CDT1,PTTG1,CENPF,TPX2,EBNA1BP2,SLC29A1,KIF2C,CCNB1,TWF2,MFSD10,FANCI,CFLAR,BCAT2,KIFC1,FARSA,PSMA6,CCNA2,GATC,BDH1,TXLNA,TIMELESS,AHCY,MAST2,AHCYL1,UBE2M,SAP30,TK1,RFC3,MKLN1,RAD51AP1,LDHA,MYBL2,PSMG1,RRM2,CDC6,GALK2,NDUFA7,SMC2,TOMM40,MCM2,VDAC1,KIF11,PSMB9,MATR3,MAT2A,PRDX1,PRIM1,MTHFD2,DHX16,PRDX3,NFIL3,COX8A,GPI,RUVBL2,PDXK,CCNB2,ESPL1,RAD51D |
| 9.204e-10 | -20.81 | GSE20727_CTRL_VS_ROS_INHIBITOR_TREATED_DC_DN | MSigDB lists | GSE20727_CTRL_VS_ROS_INHIBITOR_TREATED_DC_DN | 181 | 60 | 17377 | 2626 |
WSB2,GLT8D1,ADD1,SUCLG1,FAM53C,RHOC,RAE1,SRGN,COPE,ARID5A,PLAGL2,CBLL1,POMP,UBE4A,CCNB1,CCDC28A,MAN1A1,JAKMIP1,ASPHD2,IRF4,SLC38A5,ARPC5,RAD23B,TTC4,CDC25B,CORO1A,OSTC,CITED2,TMED2,PREB,PGAP2,ULK3,ACP2,SEC61B,PIGT,LAP3,ELL2,ASPM,DRAP1,SELPLG,TOP3A,MYBL2,RRM2,VDAC1,ICAM2,EDEM2,BUD13,DOT1L,TRAM2,HSPA4,SEC61A1,RBM47,STT3A,CDCA7L,PRDX5,DBI,ACTB,RBBP4,NRBP1,AAAS |
| 9.204e-10 | -20.81 | GSE17721_CTRL_VS_POLYIC_4H_BMDC_UP | MSigDB lists | GSE17721_CTRL_VS_POLYIC_4H_BMDC_UP | 181 | 60 | 17377 | 2626 |
C19orf53,MANBA,DNAJB2,SLC2A1,FAM76A,HAUS4,THRAP3,LCLAT1,METTL3,PARK7,TUBGCP2,TFRC,NDUFS7,DNAJB9,ANKRD28,KIFC1,RPA2,RAP1A,PCNA,SMC3,DAD1,BDH1,CLCN6,TOP1MT,POC5,IMPA2,MSH6,FDFT1,ELOF1,GPX4,PTPN18,FAM49B,BAZ2A,GALC,FAM118B,RBX1,OXR1,RRM2,GLO1,PRPF3,BICD2,ANLN,DDX39A,MBD3,CCT8,ECH1,MAPK3,PSMC4,CCDC127,HAUS8,HSPA4,CAPN7,RNF38,QRSL1,PDXK,KLHDC4,SPRYD4,AP2S1,AAAS,CCDC137 |
| 9.497e-10 | -20.77 | FLECHNER_PBL_KIDNEY_TRANSPLANT_OK_VS_DONOR_UP | MSigDB lists | FLECHNER_PBL_KIDNEY_TRANSPLANT_OK_VS_DONOR_UP | 143 | 51 | 17377 | 2626 |
NCOR2,IMMT,TXN,KLHL21,MAGED1,ARID5A,DHX9,TOP2B,UBE4A,CDIPT,OAT,RGS2,UBE2I,PSMD9,TUBGCP2,TFRC,RPL11,RAD23A,VAV1,RPN1,PA2G4,PTPN11,RPL19,ZBTB22,CYC1,SMARCE1,TMED2,MORC3,CPNE1,RPL35,DCTD,BMS1,BICD2,VDAC1,TXNL4A,KLF6,MAN2A2,DAP3,AHNAK,SYNCRIP,CHD3,TIMM17A,STK38,ITGB1,OGT,YWHAZ,ACTB,CLU,SRSF3,RBPJ,NUMB |
| 9.575e-10 | -20.77 | SASAKI_ADULT_T_CELL_LEUKEMIA | MSigDB lists | SASAKI_ADULT_T_CELL_LEUKEMIA | 164 | 56 | 17377 | 2626 |
PPIB,CHMP2A,RECQL,ANXA6,FOXM1,DYNLL1,PTTG1,CENPF,TPX2,CDK13,PAWR,KIF2C,TMED3,CCNB1,AP3S1,ETS1,MYL6B,TFRC,FZD6,DST,IRF4,PCNA,PDCD10,CCNA2,KIF14,CORO1A,MTX2,SAP30,PLK1,SGCE,TK1,TRAFD1,RFC3,HMGN4,ATP2C1,WDR18,MKI67,GALK2,CADM1,ICMT,KIF11,PRDX1,ISG15,RPA1,FAS,HINT1,ACYP1,TFDP1,STAT1,LPCAT4,HMGB2,RBBP4,CCNB2,UBE2C,TUBB,IFI16 |
| 9.575e-10 | -20.77 | WHITFIELD_CELL_CYCLE_G2 | MSigDB lists | WHITFIELD_CELL_CYCLE_G2 | 164 | 56 | 17377 | 2626 |
SKA3,HJURP,PPP1R2,KDM4A,CDCA3,CDCA8,DHX8,KIF23,DNAJB1,VPS25,CFLAR,KIFC1,CDKN2C,KIF5B,CCNA2,TMEM99,TNPO2,CDKN1B,SUCLG2,KIF22,SMC4,HP1BP3,SAP30,MND1,PSRC1,CKAP2L,NUSAP1,RANGAP1,CDCA2,BCLAF1,AURKB,FAM72B,ANLN,CCNF,BORA,KLF6,KIF11,STK17B,FADD,HAUS8,RDH11,CDC16,FAM110A,NEIL3,HIPK2,STAT1,FAM83D,H2AFX,HMGB2,KPNA2,CHEK2,WDR62,UBE2C,ESPL1,TUBB,POLQ |
| 9.719e-10 | -20.75 | ABCE1 (ATP binding cassette subfamily E member 1) | protein interactions | 6059 | 237 | 76 | 17029 | 2761 |
SRM,ZNF207,USP7,KARS,NDUFA5,IMMT,TOMM20,DYNLL1,EIF3D,HEXB,AP1B1,PRKACA,LYN,FANCI,PSMD1,EIF4A3,TIMM23,RAB35,DUT,PPP6C,SUCLG2,RP2,TECR,STRAP,RPRD1B,POC5,VDAC2,TMEM216,CUL3,MCM2,EIF3H,EPB41,SUPT16H,SURF4,PSMD8,SAFB,CORO1C,PTER,PPM1G,MAP4,ATXN2L,RNASEL,MAPK1,EWSR1,MAPRE1,FLOT1,TIMM21,NDUFA4,LMNA,EBP,KIF5B,CD59,GNS,STARD9,ARPC5,CENPJ,POLR1B,PTGES3,FBL,SMC4,STAU1,WDR1,MACF1,ABCF1,PSMB3,CIP2A,CBX3,RPL36,XRCC5,SDHB,PTPRF,RPL32,SNAP23,ACAT1,CTSA,YWHAH |
| 9.841e-10 | -20.74 | MORF_TPR | MSigDB lists | MORF_TPR | 139 | 50 | 17377 | 2626 |
PRKCSH,RAF1,TOR1AIP1,AGPAT1,NKRF,CDK13,BECN1,GGPS1,PARN,SRRT,RAB11A,PDXDC1,TUBGCP2,FANCI,SSR1,TERF2IP,TFAP4,CYHR1,PDCD10,RALB,HUWE1,PIK3R2,MEA1,ZBTB22,CPSF4,KDM3B,CSNK1G2,TSTA3,ATG9A,DRAP1,MTX1,NFATC2IP,RAB1A,PCGF1,MFN2,SEC31A,TAF2,SMAD2,SEC23IP,CHD3,STK38,TBPL1,PPP1R11,NUP62,PRPF4,ROCK1,B4GALT3,IGBP1,CSNK1D,DDB1 |
| 9.881e-10 | -20.74 | GATTGGY_V$NFY_Q6_01 | MSigDB lists | GATTGGY_V$NFY_Q6_01 | 1089 | 237 | 17377 | 2626 |
PTMS,ZBTB10,NPHP4,KDM4A,MCCC1,AP3M2,AGPAT1,ENSA,USP39,NANS,TAF6L,CNTROB,OAT,RBM4,MIS12,MBD4,BCAT2,DPYSL2,TTC9C,AKR1B1,ZBTB22,RP2,TECR,PRADC1,MOB1A,RNF26,OGG1,ARID4A,TACC3,PLK1,ERCC1,FOPNL,ZBED5,BRCA1,EAF2,WBP1,SOX4,STX16,RAB5B,USP21,GINS4,ASF1B,PAF1,SMAD2,TPP2,QRSL1,ACTB,ZSWIM3,ARRB2,PDCD4,NUMB,UBE2D3,RMND5A,HIVEP3,PRPF38B,PIGN,MUT,CLSPN,CENPF,KIF23,RACGAP1,DNAJB1,RAB6A,CNOT3,FAM192A,RNF121,INTS7,ARPC5,SSBP3,MSH2,PCYT2,PIK3IP1,MAML1,GNAI2,LUC7L2,ZNF189,FDFT1,POLR2I,SIGMAR1,ELL2,PRRC2A,C16orf72,NSDHL,CBFA2T2,EIF4G2,PATL1,SFXN5,MTR,RHOB,HMGN2,PI4K2A,CAND1,CAT,MOSPD3,ORMDL2,USP32,ARAP1,DCAF11,YWHAZ,RUFY3,NDE1,WASF2,CORO7,GGNBP2,SARNP,CYLD,TRAF7,MPHOSPH8,RAB11B,IVNS1ABP,SUZ12,CAST,ANK3,TPX2,STARD7,RMI2,ZFYVE21,TM9SF3,BCL2L1,PRKACA,STMN1,LCLAT1,PCBP1,RPAIN,ARL6IP6,CRKL,SAP130,MRPL50,SEC11A,PDK2,SHC1,IARS,MTMR4,UTP18,AKAP8,TNPO2,RPN2,RNASEH2A,FAM76B,TALDO1,ATF2,SPSB3,CGGBP1,CSTF1,RLIM,CPNE1,SLC39A9,PSRC1,COQ10B,SLC26A6,WBP2,CIRBP,NARF,ELP4,GORAB,CADM1,BICD2,OGDH,RAB1A,CHMP2B,RPS9,FKBP3,DHX57,C19orf54,TMEM184C,CHCHD3,MRPL2,PPP2R5A,DDOST,ACYP1,HNRNPR,DGCR8,FASTK,ARNTL,RPLP1,ZNF436,H2AFX,SEL1L,XRCC3,FKBP5,H3F3A,MAPK1,LRP8,OTUD5,GOLPH3L,ANXA6,SLC41A1,ZFP91,MECP2,SRSF6,TRMT6,CDK2AP2,LANCL1,DCUN1D4,IFT27,JAKMIP1,RPA2,KIF5B,ERH,GART,FUT8,TANK,NDUFS8,UPF2,C12orf75,STAT3,TPCN1,RNF5,ELOVL5,HEMK1,RHOA,NASP,HELB,PRKDC,ABCF2,WDR81,MEN1,BORA,ARL17A,SNRPA,SMAP2,HSPA1B,KPNA4,ELMO1,FAM110A,DBI,AEN,SLC25A19,LY75,KHSRP,HMGB2,RBPJ,RGL1,MBD6,UBE2C,TERF1,ESPL1 |
| 1.007e-09 | -20.72 | FOXL2 (forkhead box L2) | protein interactions | 668 | 66 | 32 | 17029 | 2761 |
HNRNPUL2,NKRF,THRAP3,UBE4A,UBE2I,TTF1,NUP205,CREM,CMSS1,SP100,IARS,BANF1,GMEB1,MRPL21,NSUN4,SRPK2,NSDHL,BTAF1,SUGP2,DNAJC9,DCUN1D5,SMC2,DDX39A,ZFR,CXXC4,DHX16,RBMX,RPLP1,SMPD4,MRPL3,CCDC59,DDX52 |
| 1.014e-09 | -20.71 | GO_MULTI_ORGANISM_METABOLIC_PROCESS | MSigDB lists | GO_MULTI_ORGANISM_METABOLIC_PROCESS | 135 | 49 | 17377 | 2626 |
RPS15,RPS2,NUP188,RPLP2,RAE1,EIF3D,MON1B,NUP54,RPL15,EIF2AK4,PCBP1,NUP205,RPL11,RPL23A,USF1,NUP210,RPL17,NUP107,RPL19,NUP153,NUP85,PCBP2,SEH1L,RPL29,EIF3L,RPL35,RPS10,RPL6,RPL8,RPL38,RPS24,NUP155,RPL27A,RPS9,EIF3G,MAP2K2,RPSA,EIF3A,RPL36,RPL37,RPL32,RPS27A,RPS14,RPLP1,NUP62,FAU,USF2,RPS26,AAAS |
| 1.020e-09 | -20.70 | central_nervous_system-brain-glioma-astrocytoma_Grade_IV | COSMIC cancer mutations | central_nervous_system-brain-glioma-astrocytoma_Grade_IV | 16307 | 2491 | 17385 | 2587 |
HECA,ZBTB10,ABCC10,HEXB,CCNL2,FBXO22,EEF2K,THAP4,RAD23B,ATP13A3,DNM2,ZNRD1,FTSJ3,USP34,CCDC57,ERCC1,NRAS,EHMT1,KIF15,HNRNPF,WDHD1,MIER2,DIDO1,MCM2,RAB22A,SMAD2,MID1IP1,RPS27A,MYO18A,OGT,MPV17,COX5A,SMAD1,ZNF75A,ANXA11,SLC25A33,SEC61G,GGA1,MUM1,CCZ1,TRIO,CUTA,RAB23,KCTD17,HAUS4,EIF2AK4,APH1B,PARN,CDC73,MYL6B,ATG4A,TMEM179B,PDXP,SMC3,GEMIN4,MVP,NUP85,PPP6R1,PABPC1,NSUN4,PPA1,IFRD1,AGGF1,FOXK1,RBM42,GTPBP4,MAP7D1,MRPL16,ELK1,EIF4H,RDH11,MAGED2,KPNA1,ETS2,TYW5,WIPI2,RUFY3,PDLIM5,ACSF2,EXOC3,RHOG,STARD7,VTI1A,C5orf30,SLC35B2,INO80E,RCOR3,LCLAT1,CPNE3,KIAA1147,RBM23,ZNF420,AHCTF1,TBC1D22A,TBC1D14,GMEB1,NSFL1C,SEPT11,GPD1L,ZC3H3,ARL5A,PDCL3,SNX8,ERMP1,EID1,IDH3A,POLR2D,HTATIP2,MEF2D,TMEM147,GSTCD,TANC1,MAT2A,VPS26B,CORO1C,NSMCE2,CAMKMT,PPP5C,PITRM1,TUBB,COMMD10,ZNF445,SRSF6,HABP4,CCM2,FLOT1,BTN3A1,ATG2B,ABHD14B,PPP1R3B,ZBTB45,HUWE1,ZNF260,NAA50,ANXA5,LTN1,UBE3B,NAP1L4,ZNF710,ST8SIA2,RPL22L1,MED22,SPTAN1,STAU1,DDX24,TACC1,MRS2,LDHA,HEBP2,LLPH,RAB3IP,TTC33,PICALM,SH3BP5,SLC19A1,ACOX1,FAM3C,AEN,PARP10,YWHAH,THAP5,GPATCH4,FAM129A,TRIM11,YTHDC2,SNX15,RBM8A,ENSA,NENF,SND1,RUFY1,TRIM65,ZER1,PRNP,KRR1,RAB8A,NUP210,NT5DC1,NOC2L,EIF5,TACC3,RYBP,VPS13B,PTPN18,MIOS,MBLAC2,SNRPB,CDC6,UTP3,PBRM1,ODC1,USP21,TRAM2,FBXO28,BCL7C,ARRDC1,ADAM9,DVL1,NUMB,ZNF564,FUBP1,C1orf74,CTU2,PARP12,ZCCHC9,CENPF,LAMTOR3,CHCHD2,NCKAP1,LYRM2,RSAD1,TNS3,SUB1,RINL,SSBP3,MBD2,XPA,AHCY,RBM3,LRSAM1,HDHD2,NTPCR,NSDHL,AMD1,CAMSAP1,ZNF761,METTL22,ICAM2,STYXL1,APPL1,BBS12,RXRB,SDHB,PCM1,GALNT2,TMEM168,NLRC5,RUVBL2,MYO9A,BTBD10,CCNB2,USP7,GLT8D1,RPLP2,SUCLG1,ARID2,TMX4,SLC2A1,ATP6V1B2,PCBP1,LYN,BCAP31,VAV1,MRPL50,TMEM69,PSMA6,ZNF473,ZNF302,BRPF3,TARDBP,BCAP29,CTDSP2,PRPF19,PPIF,KDM3B,MND1,CLCN3,BIRC3,RAB7A,ANKRD33B,PPIE,CHMP2B,VDAC1,EIF3H,TMEM201,GLOD4,IDE,DHX16,UHRF2,XRCC3,CHMP4B,PARD3,BCL2L12,MCM10,C19orf53,KLHL21,PDAP1,CDCA8,TMX3,ARF1,SLC12A9,TUBGCP2,DNAJB9,HOMER1,POLR1B,RNF5,RBM15B,PPAN,RHOA,RPRD1A,BTAF1,TOP3A,ARHGEF12,PCGF1,DDX23,RAB18,CACNB1,TRIM26,PDCD6,ATP6V1D,L3MBTL3,FAM110A,NEIL3,CTBS,BBX,IMPDH1,TAF12,NR2F2,PGAM1,HIPK3,IFI16,NUP188,TXN,H2AFZ,PNISR,PRKCSH,USP39,UBE2I,PARK7,SLC25A37,ASPHD2,ZNF428,TRA2B,SUCLG2,TAF5L,SMARCE1,ZNF800,CDC5L,ZNF524,SGCE,OSBP2,NSUN2,USP22,CLNS1A,EIF3A,ZMYM3,DOT1L,IWS1,ANKRD10,WAS,KIF18B,TPP2,C1orf109,ZMAT3,B4GALT2,PRPF38B,RECQL,C9orf78,EWSR1,GADD45G,RRM1,ACAP1,B4GALT1,CYCS,FAM136A,SUPT7L,TMEM165,NPLOC4,CNOT3,SPAG5,WDR48,RTKN,CEP104,EXOSC7,KLHL5,LRRC8D,PPP4R1,MSH2,PIGG,OSTF1,FBXL7,MRPL40,TNRC18,SYTL3,FAM171A1,APOL1,EIF5A,GCC2,PRIM2,ELL2,RDH10,MFNG,RPS24,GORASP2,CAPZA2,ADRB2,CCT8,MTR,PHF6,PFDN5,SLCO4A1,TTC13,GOLGA2,RBMX,MED15,PIAS2,APPL2,SAMD8,NUDT3,CDKN2A,ZNF511,ATXN3,RAF1,KIAA0232,C2orf49,EPM2A,CD320,CCNA2,MTMR4,BRI3,TP53BP2,AQR,RBM12B,ILKAP,CDK12,SAP30,BRD4,DRAP1,NARF,LRRC8A,ELP4,ABHD11,PKMYT1,ASB13,SERP1,TRIM28,SUPT16H,EIF3K,CHMP4A,ATF6,XRCC4,ADAM23,PRPF4B,NDUFS1,DEPDC1,MECP2,SECISBP2,HMG20A,WWP2,SLC25A36,JAKMIP1,DNAJC8,AXIN2,CITED2,JMJD4,ANKRD37,KAT2A,TMEM126B,RABIF,ADSL,PACS1,BMS1,KCNQ1,ARSK,MACF1,KIF11,KLF6,COMMD4,SMAP2,FADD,SH3GLB1,MYO1F,CBX3,TMEM127,INF2,PPP1R11,DUSP11,DDX5,WDR62,TAF6,ESPL1,PURA,DDB1,DEF6,FAM83G,IPO4,UBL3,NAT9,PIGM,LYRM4,GPR132,UBE2Q1,PTP4A3,BRIX1,MRPL19,ZNF696,SF3B2,PCYOX1L,CDC42,SYNM,GOT2,JAZF1,HADHB,RPF2,SLC35C2,CNNM3,CARM1,SRPK2,WDR41,LARS,ZCCHC10,CCDC138,LRBA,SUMF2,KMT2C,OGFR,PRPSAP1,ASF1B,RPL37,MAN2A2,EIF4ENIF1,NIP7,U2SURP,MIA2,ZNF268,ATP6V0E1,PPP1R2,PM20D2,XPNPEP3,RGS2,LYAR,FAM89B,POLR2I,TRAFD1,SUGP2,GBA,SYVN1,DAPK3,ARHGAP15,MASTL,UAP1,NFIL3,FN3KRP,YWHAZ,CTSA,TMEM14A,TOB1,TSEN15,ADNP2,TCF12,PRKAB1,MDH2,SMARCA4,ORC1,RRN3,UBXN2A,IARS,CD3EAP,KIF14,EXOSC1,CS,CLTB,DNAL4,CSTF1,POU2AF1,UBQLN4,NXT1,HPDL,PGGT1B,SELPLG,SMU1,ATXN1,GLO1,OGDH,BICD2,CADM1,EDEM2,HERPUD2,TOLLIP,FANCE,MBD3,PDHX,RPS9,ALKBH6,SURF4,DUS3L,ARNTL,ANP32E,FKBP5,TMEM101,CCDC125,ABCA1,PDCD2L,GCLM,RAE1,DCTN2,NUP54,CHIC2,PAWR,MXD4,DCUN1D4,PIP4K2A,XPR1,KIF5B,KLHL20,SEC24C,RRBP1,ARHGEF2,LDLRAD3,STAT3,MYO5A,NIPAL3,AMPD2,TXNL1,PHF20L1,DCAF6,FAM49B,TMEM39A,ATP2C1,RFFL,COG1,RCOR1,PRMT2,TFEB,LEMD2,UPF1,ELMO1,ZC3H7B,DTX4,ZMIZ1,TERF1,HRAS,CCDC93,FGFR1OP,TMED7,PIGQ,AGPAT1,CNTROB,PPP1R16B,MIS12,GSDMB,TTC9C,PDS5B,NUP153,SENP1,PGAP2,TMEM115,PLEKHM3,DCUN1D5,PLEKHF2,BRMS1,PWWP2B,TRIM47,WDR11,AXIN1,SMG9,TRIM52,LONP2,NDUFV2,PHF23,CERK,SLC4A2,EZH1,ITGB5,LMNA,MCTS1,DDX56,EIF2S2,SLC38A5,FOXN2,CARS2,PRRC2A,C16orf72,RB1CC1,ZMYND11,PGS1,MYBL2,UHRF1BP1,SRSF5,MPG,MATR3,CYB5A,NCDN,POLR2J,SETD3,TEX30,PTAR1,CNOT6,NDE1,EGLN1,ZNF207,ANKRD27,PPP1R37,ABCA3,IVNS1ABP,RMI2,MON1B,TMEM97,NIT2,NUF2,ZNF267,TCF19,TMEM161B,KTN1,APP,PRKD3,CLUAP1,ATP2A2,UTP18,GRSF1,DUT,ZCCHC2,ANAPC7,RNF19A,FAM76B,CLN6,TMEM9,GCC1,RNF169,ADCY7,ATP6V1G1,ENPP4,RNPS1,CDCA2,FKBP3,GPR137,DDX17,CHCHD3,PEX5,CDC16,HIPK2,MBOAT1,TICAM1,PDXK,ZBTB11,ANXA6,TMBIM4,GMCL1,UBE4A,IL21R,ETS1,WRB,ZNF92,PNO1,CAPN2,ADD3,SUV39H2,TTLL12,TPCN1,TMX1,LYPLA2,HNRNPM,MFSD12,LDHB,PPP3CA,NUDT8,POLK,JTB,EMP3,MTMR12,ZP3,PDE3B,KIF18A,CCDC6,WNT5B,MAPK6,LY75,C4orf46,SLC25A19,RGL1,PSAP,WDR76,IGBP1,FAF1,SNAPIN,COX15,AGRN,THOC1,GNPDA1,GPBP1L1,PPP1R15B,CSNK2A1,EBNA1BP2,GIT2,BIRC2,ATPAF1,DLG5,ABL2,XRCC2,ZFYVE27,MCMBP,PTPRK,CDC37,SP3,METTL1,EXOSC6,HARS,GMFB,ESYT1,ANLN,RAB5B,RHEB,DPYSL3,TBC1D17,TIMM13,CDCA4,TONSL,NRM,NAGLU,ACTB,ZNF45,TMUB1,CTCF,ASAH1,DOCK11,CRLF3,ASXL2,LRRC14,NUS1,SLC27A4,AFF1,MDFIC,MAML1,CYTH1,NQO2,UTP15,EIF2AK1,EIF4G2,ZDHHC3,MOSPD3,ITPRIPL1,CDC27,SNAP23,TBPL1,PRMT7,KCTD7,NDUFA5,CYLD,UGP2,DYNLL1,COPE,HCFC1R1,ZADH2,GGPS1,RPAIN,RAD23A,PDK2,ATP6V0B,STRBP,DUS4L,MRPL34,PDCD2,SAP30L,SLC39A9,CLPTM1,RPL29,RPL35,BTG2,DNAJC9,MTMR6,FRAT2,NFATC2,KDM1B,ARL5B,USP36,CCDC127,MRPL2,ATP1A1,CLK3,PSMD3,MAFK,CEP55,NDUFA11,DNAJC17,ZNF436,NCOA1,SLC25A39,ZC3HC1,ZNF146,ATXN7L2,CDC40,SMAP1,GOLIM4,RRP15,DAP,GNE,SMC6,ARFIP2,NKRF,CHAC2,BZW2,WRNIP1,SS18L1,CENPM,PTGES3,CAMK2G,MLEC,ZNF202,PPWD1,FAM50B,RHOT2,NEU1,TPD52L2,GOLGA7,TWSG1,PGRMC1,GLG1,FAM126A,RPS6KC1,UBE2C,PPCS,NDUFB6,TMEM41B,ZDHHC8,PLXNA1,CCNB1,SLC20A1,COMMD6,ABHD14A,POLR3K,C14orf119,ASAP2,SNUPN,CNPY4,TFG,PLCL2,SEH1L,ATG9A,PBK,MKI67,DDX20,AMDHD2,SLC17A5,GALNT7,CCNF,FOXRED1,RBM47,PTER,WDR4,DHTKD1,TRAF5,HDAC2,PWWP2A,HSPH1,MAPRE1,CHTF18,ADO,KIF23,SLC35B1,NOTCH2,JMY,FKBP1A,SLC31A1,SNX18,ATIC,ATP6V0A2,PIKFYVE,RNF135,LPCAT1,EEF1D,TMED2,FTL,PHF10,DDX28,ZNF84,SIGMAR1,PIP4K2C,RIT1,PLEC,KDM3A,SF3A2,FAS,EPRS,ZNF777,TMEM54,QARS,PPP3R1,TCOF1,NRBP1,CABLES1,DNMT3A,RWDD1,CKLF,TRIP10,SF3B1,RPS6KA1,SUZ12,CAST,RAC1,GPR89A,OLA1,SNN,GNB2,FLAD1,APLP2,KDM2A,TNPO2,CDKN1B,TALDO1,GPX4,ATP13A1,RFC3,MAPRE2,ERF,CUL3,SLBP,KIAA1586,H2AFV,POLG2,GAR1,PSMB9,DHX57,NSA2,HSPA4,MRPL55,JAK1,TBL3,SEL1L,H2AFX,KLHDC4,B4GALT3,PDCD11,ATMIN,POLQ,POU3F2,OTUD5,NCOR2,ANKRD13D,PKP4,SCAMP3,BABAM1,CDCA3,SLC25A12,BLM,TMCC3,GTF2F1,RPL17,CRAT,AHSA1,PRC1,UPF2,COPS7B,SLC38A10,CNOT6L,CNPY3,UBE2M,IFT46,TMEM160,TSHZ1,ZFP64,DENND4C,DENND1B,WDR18,RPL8,ILF3,LRRC1,RHOT1,MARK2,TSR2,ECH1,PRDX1,PLD3,NUCB1,GNA12,FBXO21,C1orf131,PRDX3,PFDN4,HNRNPH3,STX18,TFDP1,KHSRP,ASNA1,CPEB2,SSSCA1,BYSL,VPS29,S100PBP,MIB2,IER2,PTMS,NOP2,UBN1,DCAF15,NF1,ALKBH5,MOGS,TAF6L,MAPK14,BECN1,SNAPC4,RNF103,BCAT2,MBD4,C18orf32,METTL14,IMPAD1,ZNHIT6,RCSD1,PHTF1,SRI,KIF22,ZBTB22,NFU1,OGG1,TRIM14,ELOF1,COPS8,FYTTD1,TRIM8,RRM2,SOX4,ABHD5,CXXC4,UBTF,PAF1,UEVLD,SPATA2,PQBP1,IARS2,ATXN2L,GALNT10,STARD3NL,RPS15,PIGN,AGTRAP,CIB1,XPO7,SRRT,ZNF449,CAPZA1,GLTP,BCL2,KIFAP3,N4BP2,HP1BP3,VOPP1,THNSL1,ISG15,CAND1,GNAS,TSC1,RBM25,CDCA5,ZFP90,NANP,RBBP4,ZBTB24,SMARCD1,MBD1,WASF2,MMACHC,TOMM20,IFI27L1,GNPNAT1,MPHOSPH8,HNRNPUL2,CHD1,MEAF6,C2orf68,CCDC50,AKAP8,PARL,RPN2,CHTOP,FAM3A,F2R,TMEM14C,SCYL3,ABI1,HTRA2,MOSPD1,RLIM,FAM172A,ZNF500,PSMB7,NLN,WIPF1,BOLA1,BUD13,NDUFB1,PEF1,EIF3G,BTBD1,TAB2,CHCHD1,TULP3,WDR59,CANT1,SCARB1,GAS2,USP11,SMURF1,PPP2R2D,TSPAN5,CDS2,MAGEH1,MRPL42,EYA1,CDK2AP2,MRPS26,LETMD1,KLF13,HDDC2,RGS1,MAN1A1,FBXO5,GART,TANK,BRD7,MRPL11,SAMD4B,ZDHHC18,GTF3C6,POLR3GL,WDR81,MEN1,ZNF407,MFN2,COX8A,ZRANB2,MBD6,SRSF3,ATP6V1C1,IDH3B,TATDN1,TSC2,LACTB2,CMTM6,RBM4,ZNF275,RPL23A,CDKN2C,NAPG,USF1,MECR,AP1M1,UPRT,CRY2,ECD,RNF26,TIPARP,LRRC59,ANKRD9,RHBDD2,MGAT5,BAK1,ZNF559,RHOBTB3,GABPA,WBP1,NUTF2,ARF4,GINS4,KRIT1,BOLA3,AHNAK,RAD18,PDRG1,RNASEL,CHPF2,OAZ1,SMNDC1,PDCD4,NXT2,HIVEP3,KIAA0100,CLSPN,RHOC,DHX9,PDCD7,PSMD9,HAUS2,COPB2,TFAP4,CD59,RNFT1,RIMS3,MEGF8,FBXO7,EFTUD2,CPSF4,MRPL21,PHKG2,LUC7L2,SRSF11,EIF3L,MTA2,TYW1,USP10,ITM2A,SSR2,BCLAF1,MTX1,SFXN5,FNTA,PDLIM1,TMEM159,MRPL3,ALS2,FAM72A,TRIM41,KARS,NQO1,POC1A,ANK3,PTTG1,TPX2,TBC1D13,DAZAP2,STMN1,GLRX3,C19orf48,REPS1,ABHD16A,FBXL6,SH3BP1,MTA1,UBA5,CLCN6,INTS12,C8orf59,RPRD1B,CGGBP1,CPNE1,SEC61B,POLR2L,FAM118B,GOPC,E2F3,CIRBP,RPL38,CRNKL1,PFKFB3,GORAB,RAB1A,GIGYF1,TMEM184C,PPP2CA,KIF2A,CCDC14,LSM6,RNF38,SNRPG,DMWD,USP13,ZFP91,TRMT6,IP6K2,WDR5,SLC25A43,PMVK,IFT27,NEIL2,RRP36,SRXN1,RPA2,PSMD2,CLIC4,PDCD10,CBWD2,COQ4,ITGB8,ARF5,ARHGEF1,FBXL19,TTPAL,UTP20,MAGT1,GPS2,DBI,SSNA1,MRFAP1L1,CD81,TMEM131,WDR13,FANCI,PAPOLA,CREM,TET3,FANCL,GLIS2,IL6ST,INTS1,POP7,SLC44A1,MTPN,ASB6,PLK1,RPP25,SEPT9,CELSR2,RBX1,APH1A,RAD51AP1,CKAP2L,PSMG1,UBE2V1,EAF2,IL12RB1,KRTCAP2,LUC7L,LSG1,NECAP2,C1orf122,ALG3,TRIM4,AGPAT2,CHD3,ZNF367,E2F4,PRPF4,KPNA2,BEND6,CLN3,DNAJC30,NGLY1,POT1,MYL12B,CCDC137,RMND5A,HJURP,DNAJB2,FAM53C,NKD2,SDC2,KLC1,CDK13,ADCK5,COX4I1,DNAJB1,RAB6A,ARID1B,C1GALT1,MLX,UBE2Q2,CCP110,ZNF746,ARL6IP1,CTR9,NIPSNAP1,ABHD2,DCAF8,ACSL3,LDB1,MAP4K3,ARMC8,RBM38,NMT2,IRF5,RPL36,HAUS8,MBIP,ORMDL2,COX7A2L,ZDHHC7,SIL1,FAM122A,DTD1,UNC13C,BCCIP,SART1,TRAF7,NDUFAF2,TOR1AIP1,ZNF416,LAGE3,ZFYVE21,TM9SF3,RRAGC,ZNF121,OIP5,NRF1,WDR44,PPME1,PIN1,EFCAB11,RPAP1,CABLES2,LMAN1,AHCYL1,TOP1MT,STRAP,SPSB3,ZNF583,SNX25,ARHGAP17,POLR2G,ZNF780B,PPT1,NUP155,DCLRE1C,MRPS14,RHBDF2,SUGP1,RBL1,FASTK,UBXN2B,STK38,AP1S1,SPRYD4,SLC22A23,H3F3A,CHID1,SMAD4,RAD51D,SLC30A9,UNK,CMAS,NADSYN1,HMGN3,NCAPG,SCYL2,FZD6,HERC3,GTPBP3,CTSS,ORC3,RNLS,YTHDC1,ACP2,HMGN5,CSRP1,METTL5,ABCF2,TUFM,RANGAP1,PNPLA8,HAGH,API5,ZFR,SEC23IP,E2F1,TMEM219,USP20,RBPJ,PDCD6IP,MAX,LUZP1,ADAM10,CXXC1,TSC22D3,AP3M2,CUL1,GYG1,NANS,OAT,MYEF2,ANKRD26,PA2G4,NOL11,FIZ1,ZNF200,MARCH2,SLC26A2,SRP72,KLF10,LACTB,RFC2,CBFB,RAB2B,PRIM1,MAP3K4,HHEX,LUC7L3,RPS14,MAP4,MRPL27,BTF3,PTPDC1,CCDC59,NMD3,PTOV1,COX5B,DNAJC5,SCOC,DHPS,POLR2K,ANKH,C16orf87,VAV2,PRKAA1,GSPT2,DLGAP4,PXMP2,PRPF39,PSEN1,ZNF79,PDXDC1,VPS25,NDUFS7,YY1AP1,C12orf10,FAM192A,RPN1,LHX8,ARPC5,ZNRF2,DAPK1,TPST1,PIK3IP1,CYC1,SOCS5,FDFT1,PIGT,WDR1,EMB,ZNF574,C1orf35,EXOSC9,ARID1A,PTTG1IP,C9orf40,FXR1,GOSR1,MAP2K2,TWISTNB,AKAP1,XRCC5,HMGN2,PI4K2A,CAT,SEC31A,DERL1,HSPBP1,MTHFD2,CEBPG,ARAP1,FAM83D,USP32,CABIN1,SMPD4,GPI,CYTIP,TP53RK,REPS2,RAB11B,UROD,SLC39A13,POMP,BCL2L1,DECR1,RALB,SIAH1,ADCY9,LPIN2,SOCS6,MRPS27,TTC3,RNASEH2A,CFL1,ANKLE2,CDC123,OAF,VDAC2,EDF1,ERC1,EML4,AMZ2,ANKZF1,ZNF282,RAD51C,DSN1,DDOST,HINT1,DGCR8,SAFB,HAGHL,LMBR1,FTSJ1,RWDD4,NCLN,BEND3,EYA2,DYNC1LI2,B4GALT5,SLC41A1,MANBA,TKT,FAM76A,CBLL1,ARGLU1,LANCL1,POFUT1,FAM8A1,HEATR5B,HLA-A,EBP,RFWD3,NDUFA2,FUT8,BTF3L4,PTPN11,MRPL54,FEM1B,RPL19,CNN2,NDUFA3,MTX2,MSH6,PDLIM2,LONRF3,RFXANK,FBXO9,GUF1,RPL32,ZHX1,NDUFS5,WDR91,HIGD2A,ZBED3,RORB,POLA2,ZNF76,MTX3,COPA,HMGXB3,PHRF1,ABCB10,COMMD5,MAP1LC3B,DST,SIVA1,RAB35,GPATCH1,TCEA1,DRAM2,DEAF1,SNRNP200,NCK1,LAP3,VHL,SREK1,ARHGDIB,PITPNB,HSPB11,BRWD1,PPM1G,SH3GLB2,CRCP,BAZ1B,ACBD4,CAB39,STK11,CLU,CHEK2,ZSWIM3,TSTD2,CHPT1,MRPL13,DCAF5,CAPN1,UBE2D3,NSMCE4A,PPP1R12A,ZCCHC8,GORASP1,NACA,UBXN1,PCSK7,RPL15,THRAP3,TTF1,QSOX2,NUP205,PRPF18,CHKA,MED10,ZRANB1,MCPH1,SLC12A2,ATP6V0D1,CSNK1G3,CREG1,NUDT4,RPL6,VKORC1,SLTM,EVC2,KLHL15,SIAH2,SLC16A1,EHD4,SNRNP70,C11orf1,APOL2,N4BP2L2,SNX27,CHMP2A,CORO7,FEZ2,UCK2,PMS2,UCK1,CLCC1,EXT2,MXD1,USP5,HNRNPA2B1,SAP130,NVL,PPP6C,CYB5R1,ZNF770,EBAG9,RNF25,PCGF6,METTL2A,FAM72B,PON2,HNRNPR,HPS5,STAT6,MAPK1,BRD9,TMEM33,NAT14,DNAJC2,TRIP12,SHPRH,SCYL1,VPS45,MYO9B,GFM2,SPPL2A,FASTKD3,FGFR3,MZT2A,PPIG,ZDHHC13,TMEM99,H2AFY,ATG13,NDUFS8,ERI3,FBL,FRMD8,SLC35A1,MICAL3,TGFB1,B3GALT6,ELOVL5,HEMK1,TIMMDC1,HELB,PSPC1,MIER1,SCFD2,NDRG3,ARL17A,MTMR3,ACAT1,CENPT,PLOD3,RAB3IL1,ZSWIM6,RAB14,ADD1,MRPS15,KDM4A,XIAP,DHX8,GLUD1,ANKRD23,PABPC4,CALM2,CDK5,PSMD1,NEK6,NSRP1,RABGAP1L,SRSF4,FNIP2,KCNAB2,PCBP2,MLST8,PLK3,ZNF672,MRPL43,HSDL1,TOPORS,MCL1,SMC2,PPFIA3,ICMT,SLC50A1,STOML2,LIMK1,ZNF689,PRDX5,ATE1,MLYCD,ATP6V0C,ST3GAL2,FBXL3,TFDP2,E2F2,PFKP,AAAS,DDX42,SSRP1,MRPL9,MRPS2,STRN4,TOP2B,ZNRF3,TMED3,DDRGK1,RAVER2,GNS,INTS7,INPP5A,MCM5,PHF14,ZNF326,NAGPA,TIMM8B,ETV3,TSPAN31,DHX29,TEX10,MAN1B1,RPS10,CBFA2T2,ABCF1,RHOB,LRRC14B,DTWD1,PTPRF,SCARB2,OSBPL11,CCDC86,DUSP3,SLAIN1,MDH1,HEXA,RNF139,SNX14,ZNF296,TRERF1,UBR2,CHD1L,ACTR3,WDTC1,MYH9,CREBL2,NIPA2,PRKACA,SAFB2,ANKIB1,STAM,ARL6IP6,RAB21,SP100,ZKSCAN1,DDA1,NUP107,ANKRD13C,MAVS,CEP63,TMEM136,RBM15,ATF2,DCTN1,SHOC2,PSRC1,MAP4K4,WBP2,ATP6V0A1,DNAJA1,NDUFA7,TAZ,C19orf54,TAF2,SEC61A1,WDR7,RPLP1,CBLN2,RBMS1,FUS,GEN1,LRP8,COIL,LRCH1,GALK1,ZNF786,RPS2,SESTD1,TRAK1,JMJD6,SIKE1,AKT1S1,KRI1,FBXO3,ERH,PPP1R8,PRDM4,GTSE1,GEMIN6,DCP1A,SGCB,S100A6,IMPA2,NUDC,PDPK1,TK1,GUK1,TNFAIP3,GALC,ZNF512,KIAA0930,MRPS10,DDX39A,RPA1,ZNF862,ZNF180,KEAP1,POLE,TATDN2,PITX1,CAPN7,LRPPRC,PML,HMGB2,USF2,ANAPC4,SRM,DDX47,MCCC1,CDC42SE2,S1PR2,CDIPT,SEC16A,SSR1,LIN9,PCNA,ZNF639,TRMU,PIK3R2,ETV6,TXLNA,PPCDC,FAM86C1,MYBL1,MRPL32,CCAR1,ABCC5,PBXIP1,BAZ2A,TLK1,MRPL12,EZR,LNX2,LRP5,BRCA1,PRKRA,STX16,EPB41,OPTN,SEPT1,SOCS4,QRSL1,OSGEPL1,GLCCI1,NUDT11,GEMIN7,SEPHS2,LZTR1,RACGAP1,PPP3CB,B4GALT4,RLF,RAPGEF6,SNRNP25,RB1,VASP,MED8,VMP1,PPIL2,MEA1,TIMELESS,AHDC1,ALDH18A1,TMEM8A,ABCC1,PREB,TRAPPC9,AACS,MEMO1,KRAS,RTF1,UBE4B,NFATC2IP,LY6E,ARPC1A,ZNF174,PSMC4,GOLGA4,PALB2,SYNCRIP,PRPS2,NIPA1,TIGD2,RNF114,FOXM1,MRPL39,XAB2,SUMO2,DUSP22,COMMD8,RPL11,CSDE1,MDM2,CORO1A,METTL9,MINPP1,POC5,DVL2,GM2A,PSMA8,COQ10B,CPOX,TIGD5,SLC26A6,CYP20A1,PRPF3,TXNL4A,RPSA,SRSF1,DNAJC10,SCAP,ZNF700,PLEKHG4B,TIMM17A,FAU,LTA4H,AP2S1,USP53,INTS2,CTDP1,MIF4GD,CDT1,ARID5A,SUMF1,GGA2,AP3S1,CSNK1A1,RMI1,TFRC,PTPN2,IRF4,STARD9,GSTK1,NDUFV1,SLC1A4,CWC27,SLC35B4,DDX31,ABCD1,RPAP3,CNTN5,SNX2,ZMYM5,CCDC34,CHCHD6,BSDC1,KPNA4,CDKN2AIPNL,FBXO41,BIRC5,TFE3,SNAP29,CDCA7L,PKD2,ACADM,CHMP7,SAT2,GCSH,ZNF496,TMEM109,TAP1,NHLRC3,IKBIP,EIF1B,ELMOD2,KIFC1,DBNDD1,CYB5RL,RNASEK,CDC25B,PRADC1,DNMT1,NOL12,ORAI2,USO1,AKT2,NOL8,GNG7,AURKB,MCFD2,SLC25A5,ZFAND5,MAK16,STT3A,TMED10,PSMD8,EIF2D,ITGB1,PTPN7,UQCRH,RRS1,ARRB2,RTN3,SVIP,DDX58,WSB2,PPIB,MUT,GMFG,HLA-E,NDUFA4,MAN2B1,METTL3,CFLAR,NDUFS4,RNF121,MEX3C,KLF16,HDAC7,DAD1,BDH1,PCYT2,GNAI2,ANKHD1,TERF2,MORC3,KCTD20,SEPT8,DCTD,PKM,TOMM40,ADSS,SERTAD2,SERF2,ZFP92,NSF,DCK,ERGIC3,ACLY,LPCAT4,VCPIP1,YY1,PPP6R2,PPP6R3,MAP3K5,RNF14,CDK2,ZC3HAV1,SYS1,ZBTB37,URB2,EIF3D,MAGED1,KLHL18,ADPGK,SLC25A44,AP1B1,SDHA,PAIP2,PHC2,CRKL,MOAP1,TERF2IP,CYHR1,ZNF75D,SHC1,UCHL5,NAA35,TMBIM1,CCT2,CDKN2AIP,MKLN1,HMGN4,GALK2,CDC23,SHCBP1,AP4E1,PRDM11,VEZF1,PPP2R5A,ACYP1,STAT1,PPA2,TRIM32,RHEBL1,C1orf112,MRI1,TCF3,BRAP,AGPAT3,MYNN,SDF2L1,SPR,RAB11A,REEP5,FOXO3,MAD2L2,CCDC28A,PIP5K1C,RBM17,MAT2B,PTEN,CENPJ,TAGLN2,OSTC,CREB1,PACS2,NCOA2,SMC4,RNASEH2C,NEK7,NET1,PARP4,TBRG4,ANAPC2,RPL27A,YIF1A,SGSH,HGS,TTLL4,SLC38A7,MFAP1,CCDC69,BRWD3,ESYT2,SKA3,NPHP4,UBE2E2,HNRNPAB,PLXNC1,TMEM184B,ST13,DNAJC24,ZNF107,SLC29A1,KIF2C,AGFG1,SIRT2,FKBP2,USP48,UBQLN2,SNRPD3,CUTC,EDC3,UBLCP1,ZNF804A,RAP1A,THADA,EIF4A3,AP3S2,ATG3,DPYSL2,PPP1R12C,AKR1B1,NDUFB9,JOSD1,RP2,TTC4,TECR,ARID4A,FGFR1OP2,TIMM50,TDP1,DPM1,FOPNL,SLC16A7,WDR82,SLC25A22,STK17B,DHX15,CHAF1A,GEMIN5,COPS6,SASS6,RPS26,PSMC1,SLC12A7,TBC1D12,TM9SF4,ZNF768,UFC1,MED13L,TIA1,MEF2A,EPHX2,PITHD1,RHBDD1,NFATC3,BANF1,BUD31,ZNF335,YBX1,KNTC1,ACAD8,UBE3C,ZNF189,ALDH9A1,KDELR1,TSTA3,CIC,OXR1,PSMA1,SEPT7,TMEM241,NAP1L1,ODF2,EXOC4,KIAA1328,NUP62,PITPNA,NAA20,PTDSS1,MZT2B,PDSS2,C7orf26,TMEM106C,IMMT,ASH1L,CHERP,WDYHV1,PLAGL2,CHKB,IRF3,TWF2,PAIP1,ANKRD28,ANKLE1,FARSA,SAR1A,SCAMP4,APOOL,PDIA6,ACSL5,TOR1AIP2,AZI2,GFER,RAD54B,TMEM41A,DAP3,ZNF317,GADD45B,AKNA,REEP4,CBX4,MIF,KIF3B,GOLPH3L,SH2D3A,CASP6,TOR3A,SRGN,DBF4,MFSD10,SAC3D1,CTNNBL1,YIF1B,CLDND1,TTC17,SLC25A1,GINS1,PAQR6,CSNK1G2,TELO2,ADAM17,HMGN1,NASP,ASPM,PPP1R21,PRKAR1B,SYMPK,TARS,SNRPA,MAPK3,HSPA1B,HLA-B,ATAD2,PLAA,ZNF330,OSBPL8,KBTBD7,PREPL |
| 1.042e-09 | -20.68 | GO_REGULATION_OF_PROTEIN_COMPLEX_DISASSEMBLY | MSigDB lists | GO_REGULATION_OF_PROTEIN_COMPLEX_DISASSEMBLY | 199 | 64 | 17377 | 2626 |
ZNF207,CHMP2A,PDCD6IP,ADD1,XIAP,TPX2,MYH9,CCNB1,TWF2,STMN1,BIRC2,KIFC1,NEK6,CEP63,MTPN,PLK1,PSRC1,BIRC3,TUBGCP5,EZR,AURKB,CHMP2B,KIF2A,MID1IP1,CHD3,MAP4,CHMP4B,CHEK2,TUBB,CSNK1D,KIF3B,DCTN2,CIB1,KIF23,HAUS4,RACGAP1,TUBGCP2,HAUS2,RAB11A,SPAG5,FBXO5,PDXP,STARD9,SMC3,PRC1,CAPZA1,ARHGEF2,GLE1,SPTAN1,EIF5A,RHOA,WDR1,NEK7,ASPM,MYBL2,CAPZA2,KIF11,BORA,HAUS8,UPF1,GOLGA2,BIRC5,WDR62,ESPL1 |
| 1.045e-09 | -20.68 | Golgi subcompartment | cellular component | GO:0098791 | 820 | 185 | 18223 | 2701 |
TMED7,RAB14,COPA,ADAM10,TGOLN2,CDIPT,SEC16A,BECN1,RIC1,RAB8A,ASAP2,CDC42,RAB35,AP1M1,DNM2,AP2B1,TFG,RHBDD2,MGAT5,PLK3,PGAP2,USO1,RHOBTB3,TMEM115,NRAS,ATG9A,LAP3,APH1A,PITPNB,GALNT7,MCFD2,STX16,SLC50A1,RAB2B,RHEB,OPTN,MAN2A2,TMED10,MYO18A,ST3GAL2,GALNT10,ROCK1,CLN3,CHPT1,CHPF2,RTN3,NAA60,B4GALT2,SVIP,SCOC,AGTRAP,GORASP1,HLA-E,PCSK7,B4GALT1,SLC35B1,RAB6A,TMED3,NOTCH2,B4GALT4,PSEN1,TMEM165,QSOX2,COPG2,COPB2,CD59,C1GALT1,RNF121,TPST1,PIKFYVE,LPCAT1,PPP6R1,TMED2,PREB,KDELR1,NAGPA,CYTH1,GCC2,TRAPPC9,MAN1B1,MFNG,USF3,GORASP2,GOSR1,ZDHHC3,PI4K2A,SEC31A,SCARB2,GOLGA4,GALNT2,GOLGA2,NSF,ARAP1,ZDHHC7,VCPIP1,SAMD8,SMPD4,PPP6R3,ECPAS,CORO7,SYS1,GNPNAT1,SLC2A1,COPE,RAC1,GPR89A,VTI1A,SLC39A13,RXYLT1,SLC35B2,AP1B1,APP,EXT2,BCAP31,ANKRD28,RAB21,SAR1A,PPP6C,NSFL1C,CLTB,LMAN1,GCC1,EBAG9,CHP1,MOSPD1,CLCN3,GOPC,CUL3,PKMYT1,RAB1A,AP4E1,PEF1,ERC1,SURF4,SCAP,GOLGA8A,CANT1,AP1S1,ATF6,B4GALT3,CHID1,CSNK1D,GOLIM4,GOLPH3L,TMBIM4,B4GALT5,VPS45,ARFIP2,AGPAT3,ARF1,GGA2,RAB11A,HLA-A,MAN1A1,PDCD10,KLHL20,SEC24C,FUT8,SLC35B4,ZDHHC13,YIF1B,ST8SIA2,SLC35A1,LYPLA2,B3GALT6,MOB4,ATP2C1,RFFL,COG1,PNPLA8,SPPL2B,SH3GLB1,YIF1A,HLA-B,NUCB1,SEC23IP,PDCD6,GOLGA7,SNAP29,STX18,GLG1,PLOD3,HRAS,GPR89B,SNAPIN |
| 1.049e-09 | -20.68 | PPP1CA (protein phosphatase 1 catalytic subunit alpha) | protein interactions | 5499 | 330 | 97 | 17029 | 2761 |
CHMP2A,PPP1R37,MAX,CXXC1,PPP1R15B,TOR1AIP1,MYH9,CUL1,UBE2Z,BCL2L1,GYG1,CCNB1,PPP1R16B,STAM,UBXN2A,MDM2,PCNA,DPYSL2,LPIN2,NOC2L,NUP153,TP53BP2,TFG,PLCL2,DCTN1,CDC5L,SHOC2,DEAF1,MAPRE2,PPP1R18,MAP4K4,CUL3,MKI67,WDR82,NFATC2,CDCA2,AURKB,BRCA1,ERBIN,ANLN,TRIM28,PPP2CA,HSPA4,PDRG1,UBXN2B,AXIN1,MYO18A,ARNTL,PTPN7,PQBP1,H2AFX,OGT,ACTB,MAPK1,ZBTB11,PARD3,CTDP1,MAPRE1,PPP1R2,EIF2AK4,MAT2B,PPP1R3B,RB1,PTEN,HUWE1,PPP1R8,KIF13B,ZNF326,BCL2,CREB1,MTX2,TERF2,RPAP3,SRSF11,PPP1R9B,STAU1,KCTD20,RPS24,PACS1,SRSF5,KCNQ1,CAPZA2,LRRC1,PKM,MATR3,SF3A2,POLR2A,MAPK3,AKAP1,KIF18A,SYNCRIP,CCDC6,PPP1R11,RUVBL2,BTBD10,CDK2,YWHAH |
| 1.055e-09 | -20.67 | MORF_GPX4 | MSigDB lists | MORF_GPX4 | 53 | 27 | 17377 | 2626 |
DAP,PDAP1,RAC1,COPE,WBP2,JTB,SSR2,TMEM147,MAP2K2,GNB2,BCAP31,RHEB,NDUFV1,DDOST,PSMD8,ARF5,FASTK,BANF1,COX8A,ATP6V0C,CYC1,TECR,AP2S1,MYL12B,EEF1D,KDELR1,GPX4 |
| 1.055e-09 | -20.67 | MORF_DEAF1 | MSigDB lists | MORF_DEAF1 | 53 | 27 | 17377 | 2626 |
SRP72,DEAF1,IMMT,PRKDC,VDAC2,DCTD,XPO7,TXNL4A,TARS,PABPC4,HDDC2,NDUFS4,RAD23A,SDHB,EPRS,NDUFV1,CDC16,IARS,HNRNPR,SAFB,LRPPRC,CS,MRPS27,KHSRP,ANP32A,PTDSS1,NUDC |
| 1.063e-09 | -20.66 | MORF_PHB | MSigDB lists | MORF_PHB | 119 | 45 | 17377 | 2626 |
NUP188,PRKCSH,CIB1,AGPAT1,PARN,SRRT,TUBGCP2,USP5,EBP,TERF2IP,TFAP4,RPA2,PSMD2,DNAJC8,MEA1,CS,NAP1L4,CPSF4,MLEC,KAT2A,AATF,TSTA3,IDH3A,WDR18,BMS1,MTX1,PKMYT1,ESYT1,ELK1,PCGF1,POLR2A,MFN2,CHD3,PSMD3,TIMM17A,PPP1R11,NUP62,SCARB1,TCOF1,COPS6,B4GALT3,WDR62,CSNK1D,NUDT3,DDB1 |
| 1.068e-09 | -20.66 | GNF2_XRCC5 | MSigDB lists | GNF2_XRCC5 | 70 | 32 | 17377 | 2626 |
ZNF207,MAPRE1,POMP,SNRPD3,SF3B2,MCTS1,HNRNPA2B1,PA2G4,GRSF1,BANF1,TARDBP,PTGES3,SRSF10,IFRD1,HNRNPF,PSMB7,PSMA1,DDX39A,DHX15,TARS,XRCC5,RPA1,SRSF1,HSPB11,SYNCRIP,RBMX,U2SURP,PRPF4,SNRPG,SRSF3,MRPL3,SSRP1 |
| 1.077e-09 | -20.65 | SF3A3 (splicing factor 3a subunit 3) | protein interactions | 10946 | 131 | 50 | 17029 | 2761 |
SART1,XAB2,SF3B1,SUZ12,RAE1,TCF3,VAV2,SND1,SNRPD3,APP,GTF2F1,RBM17,PA2G4,VASP,HUWE1,MCM5,ANXA5,TTC4,ABI1,EEF1D,DCTN1,CDC5L,PRPF19,SNRNP200,SNRPB,RNPS1,WDHD1,SREK1,PRPF3,BRCA1,MATR3,SF3A2,SNRPA,DHX15,EPB41,DDX23,CAND1,HGS,HSPBP1,HNRNPR,HNRNPH3,PRPF4,FUS,ISY1-RAB43,SNRPG,SNRNP70,ZNF830,NKAPD1,DDB1,SMNDC1 |
| 1.079e-09 | -20.65 | GSE37533_PPARG1_FOXP3_VS_FOXP3_TRANSDUCED_CD4_TCELL_PIOGLITAZONE_TREATED_DN | MSigDB lists | GSE37533_PPARG1_FOXP3_VS_FOXP3_TRANSDUCED_CD4_TCELL_PIOGLITAZONE_TREATED_DN | 186 | 61 | 17377 | 2626 |
RMND5A,RAB14,GCLM,PKP4,CDC40,ZNF768,FAM53C,RPS6KA1,ATG2B,DNAJB1,XPO7,SNN,RGS2,RBM4,WRB,HMG20A,PABPC4,CRKL,GTPBP3,CLUAP1,TNS3,CTSS,NOL11,ATP2A2,THAP4,MTMR4,SIVA1,SSBP3,TANK,MDFIC,SCYL3,CTDSP2,ABCC5,PPP3CA,RHOBTB3,ERLIN1,MRS2,CIRBP,KIF15,CUL3,UBE4B,USP22,OTUD3,API5,EIF4H,DDX23,KIF2A,SLC19A1,TMEM168,ZNF330,MFAP1,RBMX,U2SURP,PIAS2,VCPIP1,MEGF9,USP20,KHSRP,YWHAZ,RBBP4,ADNP2 |
| 1.079e-09 | -20.65 | GSE36826_WT_VS_IL1R_KO_SKIN_STAPH_AUREUS_INF_UP | MSigDB lists | GSE36826_WT_VS_IL1R_KO_SKIN_STAPH_AUREUS_INF_UP | 186 | 61 | 17377 | 2626 |
COX5B,GCLM,NDUFS1,HJURP,TPX2,CDCA3,RRM1,RACGAP1,POMP,GYG1,ARF1,CCNB1,SPR,NCAPG,FANCI,FBXO5,GTF2F1,CAPN2,SLC31A1,ATP2A2,MCM5,ATIC,ALDH18A1,MYBL1,S100A6,BAK1,ABHD2,TK1,CSRP1,AATF,POLR2L,TSTA3,MAPKAPK3,MKI67,PSMB7,SEPT8,DNAJC9,NUSAP1,EAF2,ICMT,MCM2,DDX39A,MRPS14,ISG15,PSMC4,PRIM1,PSMD8,SNAP29,CEP55,ACLY,COX5A,KPNA2,GPI,PDLIM5,CCNB2,PGAM1,UBE2C,PSMC1,IPO4,DEF6,TUBB |
| 1.079e-09 | -20.65 | GSE41867_NAIVE_VS_EFFECTOR_CD8_TCELL_UP | MSigDB lists | GSE41867_NAIVE_VS_EFFECTOR_CD8_TCELL_UP | 186 | 61 | 17377 | 2626 |
HIVEP3,IMMT,HNRNPUL2,DCTN2,ORC1,C2orf49,GLRX3,ANKRD39,FBXO3,LYAR,DTL,SNUPN,FBXL6,VMP1,RALB,ZNHIT6,RAB35,SLC44A1,BTF3L4,MECR,PCYT2,CENPM,TECR,SGCB,ARL5A,SEH1L,MAPRE2,HEMK1,SIGMAR1,FAM118B,ELL2,CDC123,TSPYL4,AACS,NSDHL,E2F3,CCDC34,MRPS10,HTATIP2,CKAP2L,GLO1,MEN1,SHCBP1,DDX39A,MAP2K2,CCT8,AKAP1,CBX3,PON2,CDC16,STT3A,QARS,NFIL3,E2F1,COX5A,ANP32E,WDR76,GPI,EHD4,PSMC1,ZC3HC1 |
| 1.143e-09 | -20.59 | PAL_PRMT5_TARGETS_UP | MSigDB lists | PAL_PRMT5_TARGETS_UP | 195 | 63 | 17377 | 2626 |
PKP4,PDCD6IP,SRSF6,RRM1,LAGE3,TIA1,KIF23,RACGAP1,ARGLU1,STMN1,CALM2,RPA2,AHCY,RBM3,TARDBP,MRPL48,SPTSSA,SMARCE1,UBE2M,SLC35A1,STRAP,NUP85,CARM1,TACC3,ELOF1,PTPRK,CPNE1,PRIM2,ILF3,MKI67,TUFM,SLBP,EMP3,AURKB,PBRM1,MCM2,H2AFV,SLC25A5,EIF4G2,ODC1,KIF11,SNRPA,ECH1,SRSF1,PRIM1,HSPA4,RBL1,LUC7L3,MAP4,H2AFX,PPA2,PKD2,HMGB2,ANP32E,DTD1,KPNA2,GAS2,NDE1,NR2F2,IGBP1,CCNB2,IPO4,PTOV1 |
| 1.154e-09 | -20.58 | AI837181 (expressed sequence AI837181) | protein interactions | 107242 | 63 | 31 | 17029 | 2761 |
PPIB,HNRNPAB,PHB2,SRSF6,NACA,TKT,SRSF5,ARF1,PKM,VDAC1,DDX39A,EIF4H,DHX15,TFRC,SRSF1,CSDE1,PA2G4,AHNAK,SYNCRIP,EIF4A3,HNRNPR,GOT2,RBMX,ANXA5,DDX5,TAGLN2,RUVBL2,GPI,PDIA6,PABPC1,STRAP |
| 1.159e-09 | -20.58 | phosphate-containing compound metabolic process | biological process | GO:0006796 | 2050 | 406 | 17256 | 2622 |
RAB14,FGFR1OP,PPCS,NDUFB6,ADAM10,MAP3K7CL,PIGQ,HEXB,AGPAT1,CUL1,CCNB1,SLC20A1,PARK7,EEF2K,CDK5,PSMD1,NEK6,RAB4A,UPRT,FNIP2,SLC26A2,MAST2,CDC25B,KCNAB2,PLK3,PGAP2,NRAS,AKT2,PBK,AURKB,STOML2,MAP3K4,MKNK1,SMAD2,RPS27A,PSMD8,LIMK1,AXIN1,PTPN7,COX5A,DHTKD1,UQCRH,RNASEL,PTPDC1,SMAD1,PFKP,COX5B,NDUFV2,CLSPN,GMFG,TRIO,PRKAA1,RRM1,RAB23,CERK,NDUFA4,CYCS,EIF2AK4,PSMD9,NDUFS7,NDUFS4,PDXP,INPP5A,ATIC,PPP4R1,CTPS1,MSH2,TPST1,DAPK1,PIGG,ATP6V0A2,PCYT2,CYC1,PIKFYVE,LPCAT1,PHKG2,PPA1,MORC3,FDFT1,PIGT,COQ8A,MAPKAPK3,PGS1,PIP4K2C,DCTD,PKM,MAP2K2,PSMB3,PI4K2A,ADSS,PTPRF,DUSP3,CSK,CSNK1G1,DCK,ACLY,PPP3R1,LPCAT4,MDH1,SAMD8,SMPD4,GPI,MAP3K5,PLPP6,CDK2,NRBP1,NUDT3,KARS,TP53RK,RPS6KA1,RAF1,RAC1,OLA1,STARD7,SLC35B2,EFL1,ADPGK,PRKACA,LCLAT1,CPNE3,SDHA,APP,FLAD1,CRKL,PRKD3,CCNA2,SHC1,MTMR4,DUT,ADCY9,LPIN2,TALDO1,GPD1L,RPRD1B,CDK12,ILKAP,CFL1,ADCY7,GPX4,CPNE1,ULK3,MAP4K4,TAOK1,CUL3,ATP6V0A1,PFKFB3,GALK2,PKMYT1,NDUFA7,TAZ,PSMB9,ERC1,TRIM28,PPP2CA,JAK1,HINT1,PPP2R5A,ACYP1,GUCY1B1,HIPK2,NT5C3B,PPA2,MBOAT1,PDXK,PPP5C,EYA2,CSNK1D,PRPF4B,GALK1,NDUFS1,MECP2,CCM2,TKT,BRAP,AGPAT3,ABHD14B,IP6K2,ATP5F1B,PMVK,PLPP5,NEIL2,PIP5K1C,PPP1R3B,CCNK,ERH,PSMD2,NDUFA2,NDUFB4,PTEN,PTPN11,MAP3K14,CREB1,NDUFA3,GTF2H2,IMPA2,SPTAN1,LDHB,PDPK1,PPP3CA,TK1,GUK1,NEK7,ILF3,LDHA,ADSL,TBRG4,MTMR12,PDE3B,MARK2,GPS2,ATP5MC3,PARG,DBI,MAPK6,PML,NAXE,DUSP11,NDUFS5,PARP10,CCNC,PIGM,COX15,NF1,UQCR10,PPP1R15B,HMGXB3,CSNK2A1,PTP4A3,CDIPT,RUFY1,MAPK14,ATP5PF,UBLCP1,MBD4,ABL2,CDC42,NT5DC1,IMPAD1,PIK3R2,SLC44A1,HADHB,PPCDC,NDUFB9,OGG1,FGFR1OP2,TIMM50,PTPRK,CDC37,SRPK2,PLK1,PTPN18,DPM1,RBX1,NCK1,TLK1,GMFB,RRM2,UBE2V1,PRKRA,PRPSAP1,STK17B,MPC1,ABHD5,AGPAT2,PPM1G,CAB39,BAZ1B,STK11,CHEK2,ROCK1,CLN3,CHPT1,NUDT11,PSMC1,SEPHS2,PIGN,PPP1R12A,LAMTOR3,MEF2A,COX4I1,ADCK5,CDK13,PPP3CB,EPHX2,CHKA,NUS1,TIGAR,PYURF,BCL2,MDFIC,MAML1,ALDH18A1,HDHD2,N4BP2,CSNK1G3,NTPCR,NUDT4,PSMA1,KRAS,MAP4K3,EIF2AK1,EIF2A,STYXL1,DAPK3,MASTL,PSMC4,MBIP,PRPS2,COX7A2L,TBPL1,FN3KRP,DNPH1,ATP5F1A,NANP,NIPSNAP2,PTDSS1,NDUFA5,PRKAB1,SUCLG1,UGP2,MDH2,UCK2,ZFYVE21,UCK1,CHKB,ATP6V1B2,LYN,GGPS1,DUSP22,VAV1,PDK2,PSMA6,PPP6C,MINPP1,ABI1,CTDSP2,SCYL3,CGAS,PSMA8,PSMB7,MTMR6,OGDH,NDUFB1,TOLLIP,PDHX,ATP1A1,TAB2,CLK3,FASTK,STK38,PSMD3,NDUFA11,MAPK1,PPP2R2D,CTDP1,NADSYN1,CDS2,SH2D3A,EYA1,SCYL1,GNE,ARF1,CDK11B,CSNK1A1,SCYL2,PIP4K2A,HDDC2,PTPN2,FASTKD3,FGFR3,NDUFV1,GART,GRK2,NDUFS8,STAT3,CAMK2G,RNLS,AMPD2,TGFB1,CSNK1G2,RHOA,RPRD1A,ACP2,PRKDC,PRKAR1B,NADK2,PNPLA8,MEN1,ATP5MF,CDK11A,MAPK3,HSPA1B,MTMR3,NEK1,PLAA,BIRC5,OSBPL8,COX8A,KBTBD7,IMPDH1,ACAT1,FAM126A,RPS6KC1,PGAM1,HRAS,HIPK3 |
| 1.160e-09 | -20.57 | Tmed2 (transmembrane p24 trafficking protein 2) | protein interactions | 56334 | 116 | 46 | 17029 | 2761 |
COX5B,TMED7,GOLIM4,TMUB1,NDUFS1,PHB2,SLC2A1,TAP1,FLOT1,TMED3,SLC35B2,ATP6V1B2,SRRT,KTN1,XPR1,EBP,RPN1,PA2G4,NDUFA2,ATP2A2,NDUFB4,NVL,MRPS27,NDUFS8,RPN2,ATP6V0D1,PHF20L1,MLEC,ERLIN1,ATP2C1,VDAC2,ATP6V0A1,NDUFA7,VDAC1,VKORC1,GOSR1,CHCHD6,STOML2,CCDC127,LEMD2,TMED10,STT3A,PRDX5,FKBP5,NDUFS5,PTDSS1 |
| 1.167e-09 | -20.57 | GO_NUCLEAR_CHROMOSOME | MSigDB lists | GO_NUCLEAR_CHROMOSOME | 497 | 126 | 17377 | 2626 |
MBD1,TCF12,POLA2,DNMT3A,H2AFZ,MPHOSPH8,THOC1,SUZ12,CSNK2A1,SMARCA4,SIRT2,ORC1,INO80E,CCNB1,UBE2I,MIS12,MXD1,TERF2IP,SAP130,PCNA,SP100,UCHL5,TARDBP,TOP1MT,SMARCE1,CDC5L,PRPF19,PLK1,ERCC1,BRD4,GABPA,WBP2,WDR82,AURKB,BRCA1,SMC2,PBRM1,DCLRE1C,MCM2,GAR1,H2AFV,MBD3,TRIM28,ASF1B,GINS4,CHAF1A,BRMS1,RAD51C,SMAD2,TONSL,STAT6,E2F4,H2AFX,STAT1,UHRF2,BAZ1B,ACTB,ANP32E,XRCC3,NCOA1,BEND3,RRS1,H3F3A,POT1,SMAD4,HDAC2,RAD51D,NCOR2,MCM10,MECP2,TCF3,MEF2A,BLM,CDC73,WRNIP1,RPA2,IRF4,ADD3,SMC3,MCM5,MBD2,XPA,BUD31,MSH2,TIMELESS,H2AFY,KIFAP3,SS18L1,CREB1,ORC3,CITED2,STAT3,MSH6,TERF2,GINS1,NASP,ETV3,KAT2A,HELB,PRKDC,MTA2,LDB1,POLR3GL,EXOSC9,ARID1A,MEN1,RPA1,XRCC5,CBX3,UPF1,POLE,BIRC5,SETD3,RBMX,CDCA5,PML,LRPPRC,E2F1,HMGB2,RUVBL2,RBBP4,YY1,TERF1,PURA,DDB1,IPO4 |
| 1.172e-09 | -20.56 | SMN2 (survival of motor neuron 2, centromeric) | protein interactions | 6607 | 73 | 34 | 17029 | 2761 |
RPS2,WDYHV1,DHX9,SNRPD3,PPIG,POP7,GEMIN6,OSTF1,BCL2,GEMIN4,FBL,CHTOP,STRAP,CDC5L,SNRPB,CUL3,ILF3,DDX20,SRSF5,GAR1,POLR2A,GEMIN5,RBM25,SYNCRIP,LSM6,HNRNPR,ZRANB2,SNRPG,SNRNP70,COPS6,COIL,BYSL,FUBP1,GEMIN7 |
| 1.173e-09 | -20.56 | GSE15930_STIM_VS_STIM_AND_IL-12_24H_CD8_T_CELL_UP | MSigDB lists | GSE15930_STIM_VS_STIM_AND_IL-12_24H_CD8_T_CELL_UP | 182 | 60 | 17377 | 2626 |
SEPHS2,KIF3B,C9orf78,MRPL9,COPA,GNPNAT1,IVNS1ABP,COPE,ASAH1,DNAJB1,LACTB2,ARF1,ATP6V1B2,KTN1,PIP4K2A,MBD4,MAT2B,PTPN2,FKBP1A,SEC11A,AKAP8,RAB4A,PPP6C,BTF3L4,BRD7,PDCD2,MAST2,NFU1,ATF2,SAP30L,NCOA2,PTPN18,GABPA,LDB1,PPIE,EMP3,DNAJC9,NUSAP1,GALK2,DNAJA1,NUTF2,DCUN1D5,SEPT7,ANLN,MRPS14,MATR3,ASF1B,MKNK1,POLR2J,LUC7L3,MRPL27,CDCA5,LY75,HMGB2,ROCK1,RBBP4,MRPL13,PGAM1,S100PBP,DDX52 |
| 1.180e-09 | -20.56 | RPS5 (ribosomal protein S5) | protein interactions | 6193 | 175 | 61 | 17029 | 2761 |
RPS15,RPS2,CYLD,NOP2,RPLP2,DYNLL1,DHX9,RPL15,CUL1,SPDL1,ATP6V1B2,GFM2,CDC73,PNO1,RPL11,RPL23A,KRR1,RPA2,RPL17,PIK3R2,MSH2,RPL19,POLR1B,FBL,MRPL11,HNRNPM,SLC25A1,NOL12,EIF3L,RPL35,VHL,RPS10,RPL6,TUFM,CUL3,RPL8,RPL38,MRPS10,RPS24,BRCA1,ADRB2,EIF2A,MCM2,RPL27A,RPS9,RPSA,RPA1,RPL36,CAND1,SEC61A1,RPS27A,RPS14,RPLP1,H2AFX,FUS,RRS1,CDK2,SMURF1,RPS26,MRPL3,DYNC1LI2 |
| 1.186e-09 | -20.55 | signal transduction in response to DNA damage | biological process | GO:0042770 | 107 | 42 | 17256 | 2622 |
MIF,FOXM1,BABAM1,CCNB1,CNOT11,MAPK14,FOXO3,MAD2L2,CNOT3,DTL,TFAP4,BABAM2,MDM2,PCNA,SP100,CENPJ,CDKN1B,GTSE1,CEP63,CNOT6L,CARM1,CDC5L,PRPF19,PLK3,PGAP2,PLK1,PRKDC,BTG2,USP10,BRCA1,SOX4,CNOT9,RPS27A,E2F4,HIPK2,TFDP1,PML,E2F1,CNOT6,CHEK2,TFDP2,CDK2 |
| 1.200e-09 | -20.54 | TERF2 (telomeric repeat binding factor 2) | protein interactions | 7014 | 264 | 82 | 17029 | 2761 |
TOR1AIP1,MYH9,ORC1,UBE2I,SEC16A,PCBP1,PABPC4,EDC3,SF3B2,TERF2IP,DST,SP100,SIAH1,TALDO1,RPRD1B,CARM1,CDC37,HMGN4,IDH3A,BRCA1,TAF2,TRIM47,HSPA4,BRD2,CLK3,PPM1G,WDR4,H2AFX,KPNA2,PITRM1,POT1,NUMB,CCDC137,HSPH1,SRSF6,MECP2,CENPF,CDK13,HMGN3,SDF2L1,THRAP3,HDGFL2,BLM,WDR5,NEXMIF,LYAR,TFAP4,RPA2,ERH,SUB1,SMC3,KIF13B,ANXA5,ABCD1,ORC3,FBL,TERF2,RBM15B,SRSF11,CYFIP1,HMGN1,NASP,DDX24,TOP3A,DDX39A,MACF1,SLTM,RPA1,HMGN2,XRCC5,FBXO21,OSBPL11,PRDX3,ACLY,TBPL1,DUSP11,TCOF1,YY1,SNRNP70,HEXA,TERF1,DDB1 |
| 1.202e-09 | -20.54 | RPS11 (ribosomal protein S11) | protein interactions | 6205 | 171 | 60 | 17029 | 2761 |
RPS15,RPS2,CYLD,MPHOSPH8,RPLP2,EIF3D,AGO2,DHX9,RPL15,CUL1,SND1,EIF1B,APP,RPL11,RPL23A,KRR1,DDX56,MDM2,EIF4A3,RPL17,AHSA1,ZNF746,RPL19,TARDBP,MAP3K14,FBL,HNRNPM,CDC5L,RPL35,VHL,PRKDC,SF3B6,RPS10,RPL6,TUFM,TOP3A,CUL3,RPL8,RPL38,RPS24,BRCA1,MCM2,RPL27A,RPS9,RPSA,CAND1,RPL36,RPL37,RPL32,RPS27A,RPS14,RPLP1,IMPDH1,RUVBL2,COPS6,CDK2,MAPK1,SMURF1,RPS26,PRPF4B |
| 1.202e-09 | -20.54 | single-stranded DNA binding | molecular function | GO:0003697 | 106 | 42 | 17224 | 2647 |
MCM10,TWNK,PMS2,DHX9,BLM,PCBP1,MYEF2,PARK7,RAD23A,TERF2IP,HNRNPA2B1,RPA2,SUB1,SSBP3,XRCC2,RAD23B,MSH2,NABP2,NABP1,CRY2,YBX1,TERF2,TDP1,ERCC1,POLR2G,PRIM2,RAD51AP1,POLR2D,RTF1,PRIM1,RPA1,RAD51C,NEIL3,LRPPRC,RBMS1,HMGB2,XRCC3,POT1,PURA,TERF1,RAD51D,FUBP1 |
| 1.204e-09 | -20.54 | RPS3A (ribosomal protein S3A) | protein interactions | 6189 | 238 | 76 | 17029 | 2761 |
NOP9,CYLD,RPLP2,CUL1,NENF,SND1,UBE2I,EIF1B,PABPC4,RPL11,RPL23A,KRR1,CCDC50,TARDBP,ZC3H3,NOL12,RPL29,RPL35,VHL,VDAC2,RPL38,CUL3,BRCA1,MCM2,EDEM2,SLC25A5,RPS9,RPSA,MAT2A,EIF3A,ASF1B,ZNF317,PDRG1,RPS27A,RPS14,RPLP1,H2AFX,RRS1,ARRB2,SMURF1,RPS26,NIFK,RPS15,RPS2,RPL15,ATP5F1B,LMNA,LYAR,RPA2,DDX56,HUWE1,RPL17,AHSA1,RBM34,RPL19,PABPC1,PPAN,STAU1,ZNF512,RPL8,ILF3,RPL6,RPS10,RPS24,RPL27A,KIF11,CAND1,RPL36,RPA1,NAP1L1,HGS,RPL32,CDK2,CD81,ZC3HAV1,GPATCH4 |
| 1.211e-09 | -20.53 | GO_CELLULAR_AMIDE_METABOLIC_PROCESS | MSigDB lists | GO_CELLULAR_AMIDE_METABOLIC_PROCESS | 684 | 162 | 17377 | 2626 |
MRPS15,HEXB,MCCC1,EIF1B,BECN1,RBM4,MRPL19,PABPC4,SLC25A37,RPL23A,EEF2K,EIF5,MRPL32,PCBP2,LARS,HARS,MRPL12,MRPL43,SLC25A22,SLC25A5,EIF3A,RPL37,RPS27A,RPS14,EIF2D,MRPL27,IARS2,QRSL1,ST3GAL2,CLN3,MRPL13,RPS26,SLC25A33,RPS15,MRPL9,MRPS2,DHPS,NACA,GSPT2,CERK,PCSK7,RPL15,ASAH1,EIF2AK4,PSEN1,MCTS1,EIF2S2,ATIC,EFTUD2,MRPL48,MRPL40,MRPL21,PPA1,PABPC1,EEF1D,CARS2,EIF5A,EIF3L,NOA1,DHX29,RPS10,RPL6,GBA,RPS24,MRPL16,EIF2A,EIF4H,EIF4G2,ABCF1,RPL36,EPRS,MTHFD2,ORMDL2,QARS,SAMD8,SMPD4,MRPL3,KARS,RPLP2,MRPL39,EIF3D,NIT2,SLC25A44,PAIP1,RPL11,MRPL50,SEC11A,FARSA,IARS,MRPL34,MRPS27,CLN6,GM2A,HTRA2,RPL29,RPL35,CDC123,RPL38,NLN,GLO1,NDUFA7,POLG2,MRPS14,RPS9,EIF3G,RPSA,EIF3H,EIF3K,PPP2CA,MRPL2,DAP3,IDE,MRPL55,CERS6,CHCHD1,PPA2,RPLP1,FTSJ1,FAU,LTA4H,SLC25A39,PDF,GCLM,RPS2,MRPL42,MRPS26,SLC25A12,SECISBP2,CHAC2,SLC25A43,GFM2,SLC25A36,SPPL2A,GSTK1,GART,CLIC4,GATC,ITGB8,RPL17,RRBP1,MRPL54,RPL19,ST8SIA2,MRPL11,GTF2H2,RPL22L1,SLC25A1,GALC,RPL8,TUFM,MRPS10,RPL27A,HAGH,GUF1,SPPL2B,TARS,NEU1,SLC19A1,RPL32,SLC25A19,SPCS3,CPEB2 |
| 1.226e-09 | -20.52 | NOP2 (NOP2 nucleolar protein) | protein interactions | 4839 | 151 | 55 | 17029 | 2761 |
NIFK,DDX47,RPS2,CYLD,MPHOSPH8,SUZ12,MECP2,SUMO2,DHX8,RPL15,CUL1,EBNA1BP2,BRIX1,UBE2I,RBM4,LMNA,RPL11,RPL23A,KRR1,DDX56,MCM5,RBM34,ZNF746,NOC2L,RPF2,RPL19,TARDBP,FBL,ZC3H3,FTSJ3,HP1BP3,CDC5L,SRPK2,NOL12,DDX24,ZNF512,MAP4K4,RPL6,GTPBP4,CUL3,RPL8,BRCA1,MAK16,CAND1,NSA2,SYNCRIP,NIP7,DGCR8,CDCA7L,SRSF3,RRS1,CDK2,ZC3HAV1,GPATCH4,SSRP1 |
| 1.226e-09 | -20.52 | GO_ORGANONITROGEN_COMPOUND_BIOSYNTHETIC_PROCESS | MSigDB lists | GO_ORGANONITROGEN_COMPOUND_BIOSYNTHETIC_PROCESS | 948 | 211 | 17377 | 2626 |
SRM,COX15,PPCS,AGRN,MRPS15,GLUD1,OAT,EIF1B,RBM4,MRPL19,PABPC4,SLC25A37,RPL23A,BCAT2,EEF2K,GOT2,SLC44A1,PPCDC,UPRT,SLC26A2,SPTSSA,EIF5,MRPL32,PCBP2,ABCC5,LARS,HARS,MRPL12,MRPL43,SLC25A22,SLC25A5,ODC1,EIF3A,STOML2,RPL37,RPS27A,RPS14,EIF2D,MRPL27,IARS2,QRSL1,ST3GAL2,CHPT1,MRPL13,CHPF2,RPS26,OAZ1,SLC25A33,B4GALT2,SEPHS2,RPS15,MRPL9,MRPS2,DHPS,NACA,GSPT2,SDC2,RPL15,B4GALT1,EIF2AK4,B4GALT4,RSAD1,CHKA,MCTS1,EIF2S2,ATIC,EFTUD2,ATP6V0A2,AHCY,MRPL48,MRPL40,ALDH18A1,MRPL21,PPA1,PABPC1,EEF1D,ALDH9A1,CARS2,EIF5A,EIF3L,NOA1,DHX29,AMD1,RPS10,RPL6,GBA,RPS24,DCTD,MRPL16,THNSL1,EIF2A,EIF4H,EIF4G2,ABCF1,MTR,RPL36,ADSS,EPRS,MTHFD2,DCK,QARS,TYW5,TBPL1,SAMD8,SMPD4,HEXA,PTDSS1,MRPL3,MMACHC,KARS,RPLP2,MRPL39,EIF3D,UROD,UCK2,UCK1,CHKB,SLC35B2,SLC25A44,EXT2,PAIP1,RPL11,MRPL50,FLAD1,FARSA,IARS,DUT,ADCY9,LPIN2,MRPL34,MRPS27,TMEM14C,PDCL3,ADCY7,RPL29,RPL35,CDC123,CPOX,RPL38,ATP6V0A1,NDUFA7,POLG2,MRPS14,RPS9,EIF3G,RPSA,EIF3H,MAT2A,EIF3K,MRPL2,ALDH3B1,DAP3,MRPL55,CERS6,CHCHD1,PPA2,RPLP1,FTSJ1,PDXK,FAU,B4GALT3,SLC25A39,PDF,GCLM,NADSYN1,RPS2,MRPL42,B4GALT5,MRI1,MRPS26,SLC25A12,SECISBP2,CHAC2,SPR,SLC25A43,GFM2,SLC25A36,MAT2B,GSTK1,ERH,GART,GATC,RPL17,RRBP1,MRPL54,RPL19,ST8SIA2,MRPL11,GTF2H2,RPL22L1,SLC25A1,TGFB1,B3GALT6,AMPD2,CSNK1G2,TK1,GUK1,RPL8,TUFM,MRPS10,ADSL,RPL27A,GUF1,HAGH,TARS,RPL32,OAZ2,SLC25A19,IMPDH1,ACADM,CPEB2 |
| 1.234e-09 | -20.51 | RBM39 (RNA binding motif protein 39) | protein interactions | 9584 | 155 | 56 | 17029 | 2761 |
RPS2,PNISR,CHERP,KMT2E,SF3B1,SUZ12,TCF3,CUL1,USP39,JMJD6,SND1,SEC16A,APP,PHC2,RPA2,RBM23,MLX,CTNNBL1,SP100,PPIG,AHSA1,ZNF746,GPATCH1,KHDC4,TRA2B,ZBTB22,TARDBP,MCPH1,CDK12,LUC7L2,CDC5L,PRPF19,SRPK2,SRSF11,SNRNP200,ZCCHC10,LAP3,SMU1,RNPS1,CUL3,ILF3,SREK1,PRPF3,SEPT7,RPL27A,SF3A2,SRSF1,RPA1,XRCC5,CAND1,GOLGA2,RBM25,RPS14,RRS1,SNRNP70,NKAPD1 |
| 1.252e-09 | -20.50 | GSE35685_CD34POS_CD38NEG_VS_CD34POS_CD10NEG_CD62LPOS_BONE_MARROW_UP | MSigDB lists | GSE35685_CD34POS_CD38NEG_VS_CD34POS_CD10NEG_CD62LPOS_BONE_MARROW_UP | 191 | 62 | 17377 | 2626 |
UBL3,CMAS,PRPF38B,DNMT3A,SMAP1,ADD1,MRPL42,C5orf30,GLUD1,OAT,STAM,ANKRD28,CAPN2,SNRNP25,APLP2,FUT8,ADCY9,MECR,TRA2B,TTC3,TTC17,TALDO1,SPTSSA,ARL5A,TMBIM1,TACC3,MYO5A,ALDH9A1,SPTAN1,SAP30,EIF3L,BRD4,DENND4C,PPP1R21,LRBA,RPL6,MKI67,CUL3,KCTD20,EMP3,CADM1,PLEC,MATR3,CYB5A,PRDX1,RPL36,ADSS,PON2,RAB18,AHNAK,EIF2D,CAPN7,PGRMC1,CAB39,ACADM,YWHAH,RPS26,SNX14,GCSH,DDB1,HDAC2,TMEM131 |
| 1.292e-09 | -20.47 | BURTON_ADIPOGENESIS_3 | MSigDB lists | BURTON_ADIPOGENESIS_3 | 100 | 40 | 17377 | 2626 |
MCM10,NQO1,RRM1,CDCA8,RACGAP1,KIF2C,CCNB1,TCF19,DTL,PCNA,MCM5,PRC1,KIF22,DNMT1,TACC3,PLK1,TK1,NASP,RNASEH2C,RAD51AP1,MKI67,SLBP,RRM2,CDC6,NUSAP1,LRP5,BRCA1,SMC2,MCM2,CCNF,KIF11,ASF1B,PRIM1,BIRC5,DCK,TFDP1,KPNA2,HMGB2,CCNB2,ABCA1 |
| 1.292e-09 | -20.47 | KEGG_OXIDATIVE_PHOSPHORYLATION | MSigDB lists | KEGG_OXIDATIVE_PHOSPHORYLATION | 100 | 40 | 17377 | 2626 |
NDUFA5,COX15,NDUFV2,COX5B,NDUFS1,NDUFB6,UQCR10,NDUFA4,COX4I1,ATP6V1B2,SDHA,NDUFS7,NDUFS4,ATP6V0B,NDUFV1,NDUFA2,NDUFB4,ATP6V0A2,NDUFB9,NDUFS8,CYC1,NDUFA3,ATP6V0D1,PPA1,ATP6V1G1,ATP6V0A1,NDUFA7,NDUFB1,SDHB,ATP6V1D,COX7A2L,NDUFA11,COX8A,PPA2,COX5A,ATP6V0C,UQCRH,NDUFS5,ATP6V1C1,ATP6V0E1 |
| 1.315e-09 | -20.45 | P-loop_NTPase | interpro domains | IPR027417 | 847 | 191 | 18492 | 2768 |
RAB14,DDX47,ABCC10,YTHDC2,TAP1,DHX8,ABCB10,KIF2C,KIFC1,UTP25,DLG5,RAB8A,CMSS1,RAP1A,CDC42,EIF4A3,RAB35,RAB4A,PARPBP,XRCC2,DNM2,KIF22,ABCC5,SNRNP200,NRAS,RHOBTB3,SEPT9,KIF15,DDX20,CDC6,SMC2,MCM2,RFC2,RAB5B,LSG1,RAB22A,DHX15,RAB2B,RHEB,ARF4,SEPT1,KIF18B,CHD3,MYO18A,VPS4A,PSMC1,LONP2,DDX42,DDX58,RECQL,CHTF18,RHOC,GSPT2,RAB23,DHX9,KIF23,RAB6A,DDX56,SMC3,MCM5,KIF13B,EFTUD2,MSH2,DAPK1,CTPS1,TPST1,GNAI2,N4BP2,ABCC1,DDX28,NTPCR,NOA1,DHX29,GTPBP4,SEPT8,KRAS,THNSL1,RIT1,SEPT7,ABCF1,RHOB,PSMC4,GNAS,ADSS,NSF,DCK,NLRC5,ATP5F1A,RUVBL2,EHD4,MYO9A,N4BP2L2,RHOG,ABCA3,RAB11B,HNRNPUL2,CHD1L,RAC1,UCK2,OLA1,SMARCA4,UCK1,MYH9,RRAGC,ORC1,EFL1,ATP6V1B2,CHD1,CBWD5,RAB21,SAR1A,NVL,RALB,KIF14,SEPT11,TAP2,AQR,ARL5A,RFC3,RAB7A,PFKFB3,RAB1A,ARL5B,DHX57,RAD54B,DDX17,KIF2A,RAD51C,DAP3,DHX16,RAB24,CBWD1,XRCC3,ABCA1,DYNC1LI2,RAD51D,POLQ,RHEBL1,KIF3B,SHPRH,TWNK,TOR3A,SMC6,MYO9B,ATP5F1B,ARF1,BLM,PMVK,IFT27,GFM2,RAB11A,WRNIP1,KIF5B,GTPBP3,STARD9,CBWD2,ARF5,ABCD1,DDX31,MYO5A,MSH6,SMC4,TK1,RHOA,DDX24,GUK1,HELB,ASPM,BTAF1,ABCF2,TUFM,BMS1,RHOT1,KIF11,GUF1,DDX39A,RHOT2,ARL17A,MFN2,MYO1F,DDX23,GNA12,RAB18,CACNB1,UPF1,KIF18A,ATAD2,ASNA1,DDX5,HRAS,DDX52 |
| 1.342e-09 | -20.43 | GNF2_APEX1 | MSigDB lists | GNF2_APEX1 | 85 | 36 | 17377 | 2626 |
MRPL9,H2AFZ,HNRNPAB,SUZ12,EIF3D,SUMO2,CHD1L,SNRPD3,PSMA6,NOL11,MCM5,DUT,GRSF1,TRA2B,TARDBP,FBL,WDR41,SRSF10,SRP72,EIF3L,HMGN1,MRPL16,H2AFV,DHX15,EIF3A,SUPT16H,HMGN2,SRSF1,HINT1,SYNCRIP,HNRNPR,QARS,RBMX,U2SURP,SRSF3,BTF3 |
| 1.343e-09 | -20.43 | GO_SPINDLE_ASSEMBLY | MSigDB lists | GO_SPINDLE_ASSEMBLY | 67 | 31 | 17377 | 2626 |
ZNF207,KIF3B,RHOA,BIRC3,ASPM,NEK7,XIAP,TPX2,TUBGCP5,MYBL2,KIF23,RACGAP1,HAUS4,AURKB,KIF11,RAB11A,HAUS2,TUBGCP2,BIRC2,HAUS8,FBXO5,KIFC1,KIF2A,STARD9,NEK6,GOLGA2,BIRC5,CEP63,CHEK2,TUBB,CSNK1D |
| 1.345e-09 | -20.43 | GNF2_HMMR | MSigDB lists | GNF2_HMMR | 47 | 25 | 17377 | 2626 |
PLK1,RFC3,FOXM1,ASPM,CENPF,CDCA3,MKI67,RRM1,CDCA8,RRM2,NUSAP1,AURKB,SMC2,MCM2,SHCBP1,KIF11,CCNA2,PCNA,KIF18B,BIRC5,PRC1,CCNB2,UBE2C,ESPL1,SMC4 |
| 1.354e-09 | -20.42 | REACTOME_INFLUENZA_LIFE_CYCLE | MSigDB lists | REACTOME_INFLUENZA_LIFE_CYCLE | 136 | 49 | 17377 | 2626 |
RPS15,RPS2,NUP188,RPLP2,POLR2K,RAE1,NUP54,RPL15,NUP205,RPL11,RPL23A,GTF2F1,NUP210,RPL17,GRSF1,NUP107,RPL19,NUP153,NUP85,SEH1L,RPL29,POLR2I,RPL35,POLR2L,POLR2G,RPS10,RPL6,POLR2D,RPL8,RPL38,RPS24,NUP155,RPL27A,RPS9,RPSA,POLR2A,HSPA1B,RPL36,RPL37,KPNA1,RPL32,POLR2J,RPS27A,RPS14,RPLP1,NUP62,FAU,RPS26,AAAS |
| 1.371e-09 | -20.41 | nuclear envelope organization | biological process | GO:0006998 | 81 | 35 | 17256 | 2622 |
CHMP2A,NDC1,NUP188,RAE1,TOR1AIP1,NUP54,CCNB1,LMNA,NUP205,ANKLE1,UBXN2A,NUP210,NEK6,BANF1,NUP107,NSFL1C,NUP153,TARDBP,NUP85,SEH1L,DCTN1,ANKLE2,PLK1,NUP155,PPP2CA,LEMD2,UBXN2B,NUP62,CHMP4B,VPS4A,CHMP7,CCNB2,REEP4,NUP58,AAAS |
| 1.451e-09 | -20.35 | GCM_ACTG1 | MSigDB lists | GCM_ACTG1 | 116 | 44 | 17377 | 2626 |
USP7,H2AFZ,SUZ12,SUMO2,NACA,DHX9,SNRPD3,PCBP1,RPL11,EBP,HNRNPA2B1,RPL17,DUT,TRA2B,RPL19,HNRNPM,CFL1,RPL29,HMGN1,RHOA,POLR2G,SNRPB,CUL3,RPL6,PSMA1,SSR2,RPS24,BCLAF1,FXR1,EIF4H,CBFB,DDX39A,EIF4G2,TRIM28,SNRPA,PSMB3,HMGN2,NAP1L1,RPL32,RPS27A,QARS,TATDN2,UQCRH,YWHAZ |
| 1.458e-09 | -20.35 | central_nervous_system-brain-glioma | COSMIC cancer mutations | central_nervous_system-brain-glioma | 15942 | 2446 | 17385 | 2587 |
HECA,ZBTB10,ABCC10,HEXB,CCNL2,FBXO22,EEF2K,RAD23B,ATP13A3,ZNRD1,FTSJ3,USP34,ERCC1,NRAS,EHMT1,KIF15,WDHD1,MIER2,DIDO1,MCM2,RAB22A,SMAD2,MID1IP1,RPS27A,MYO18A,OGT,MPV17,COX5A,SMAD1,ZNF75A,ANXA11,SLC25A33,SEC61G,GGA1,MUM1,TRIO,CUTA,RAB23,KCTD17,HAUS4,EIF2AK4,APH1B,CDC73,MYL6B,ATG4A,TMEM179B,PDXP,SMC3,GEMIN4,MVP,NUP85,PABPC1,NSUN4,PPA1,IFRD1,AGGF1,FOXK1,RBM42,GTPBP4,MAP7D1,MRPL16,ELK1,EIF4H,RDH11,MAGED2,KPNA1,ETS2,TYW5,WIPI2,RUFY3,PDLIM5,ACSF2,EXOC3,RHOG,STARD7,VTI1A,C5orf30,SLC35B2,INO80E,RCOR3,LCLAT1,CPNE3,KIAA1147,RBM23,ZNF420,AHCTF1,TBC1D22A,TBC1D14,GMEB1,NSFL1C,SEPT11,GPD1L,ZC3H3,ARL5A,PDCL3,SNX8,ERMP1,EID1,IDH3A,POLR2D,HTATIP2,MEF2D,TMEM147,GSTCD,TANC1,MAT2A,VPS26B,NSMCE2,CORO1C,CAMKMT,PPP5C,PITRM1,TUBB,COMMD10,ZNF445,SRSF6,HABP4,CCM2,FLOT1,BTN3A1,ATG2B,ABHD14B,PPP1R3B,ZBTB45,HUWE1,ZNF260,NAA50,ANXA5,LTN1,UBE3B,NAP1L4,ZNF710,ST8SIA2,SPTAN1,STAU1,DDX24,TACC1,MRS2,LDHA,HEBP2,LLPH,RAB3IP,TTC33,PICALM,SH3BP5,SLC19A1,ACOX1,FAM3C,AEN,PARP10,YWHAH,THAP5,GPATCH4,FAM129A,TRIM11,YTHDC2,SNX15,RBM8A,ENSA,NENF,SND1,RUFY1,TRIM65,ZER1,PRNP,KRR1,RAB8A,NUP210,NT5DC1,NOC2L,EIF5,TACC3,VPS13B,PTPN18,MIOS,MBLAC2,SNRPB,CDC6,UTP3,PBRM1,ODC1,USP21,TRAM2,FBXO28,BCL7C,ARRDC1,ADAM9,DVL1,NUMB,ZNF564,FUBP1,C1orf74,PARP12,ZCCHC9,CENPF,LAMTOR3,CHCHD2,NCKAP1,LYRM2,RSAD1,TNS3,SUB1,RINL,SSBP3,KIF13B,MBD2,XPA,AHCY,RBM3,LRSAM1,HDHD2,NTPCR,NSDHL,AMD1,CAMSAP1,ZNF761,METTL22,ICAM2,STYXL1,APPL1,BBS12,ANKRD46,RXRB,SDHB,PCM1,GALNT2,TMEM168,NLRC5,RUVBL2,MYO9A,BTBD10,CCNB2,USP7,GLT8D1,RPLP2,SUCLG1,ARID2,TMX4,SLC2A1,ATP6V1B2,PCBP1,LYN,BCAP31,VAV1,TMEM69,MRPL50,PSMA6,ZNF473,BRPF3,TARDBP,BCAP29,CTDSP2,PRPF19,PPIF,KDM3B,MND1,CLCN3,BIRC3,RAB7A,ANKRD33B,PPIE,CHMP2B,VDAC1,EIF3H,TMEM201,GLOD4,IDE,DHX16,UHRF2,CHMP4B,XRCC3,PARD3,BCL2L12,C19orf53,MCM10,KLHL21,PDAP1,TMX3,CDCA8,ARF1,SLC12A9,TUBGCP2,DNAJB9,HOMER1,POLR1B,RNF5,RBM15B,PPAN,RHOA,RPRD1A,BTAF1,TOP3A,ARHGEF12,PCGF1,DDX23,RAB18,CACNB1,TRIM26,PDCD6,ATP6V1D,L3MBTL3,FAM110A,NEIL3,CTBS,BBX,IMPDH1,TAF12,NR2F2,PGAM1,HIPK3,IFI16,NUP188,TXN,H2AFZ,PRKCSH,USP39,UBE2I,PARK7,SLC25A37,ASPHD2,ZNF428,RAB4A,TRA2B,SUCLG2,TAF5L,SMARCE1,CDC5L,ZNF524,SGCE,OSBP2,NSUN2,USP22,CLNS1A,EIF3A,ZMYM3,DOT1L,IWS1,ANKRD10,WAS,KIF18B,TPP2,C1orf109,ZMAT3,B4GALT2,PRPF38B,RECQL,C9orf78,EWSR1,GADD45G,RRM1,ACAP1,B4GALT1,CYCS,FAM136A,SUPT7L,TMEM165,NPLOC4,CNOT3,WDR48,SPAG5,RTKN,CEP104,EXOSC7,KLHL5,LRRC8D,PPP4R1,MSH2,PIGG,FBXL7,OSTF1,MRPL40,TNRC18,SYTL3,FAM171A1,APOL1,EIF5A,GCC2,PRIM2,ELL2,RDH10,MFNG,RPS24,GORASP2,CAPZA2,ADRB2,CCT8,MTR,PHF6,PFDN5,SLCO4A1,TTC13,GOLGA2,RBMX,MED15,PIAS2,APPL2,SAMD8,NUDT3,CDKN2A,ZNF511,ATXN3,RAF1,KIAA0232,C2orf49,EPM2A,CD320,CCNA2,MTMR4,BRI3,TP53BP2,AQR,RBM12B,ILKAP,CDK12,SAP30,BRD4,DRAP1,NARF,LRRC8A,ELP4,ABHD11,PKMYT1,ASB13,SERP1,TRIM28,SUPT16H,EIF3K,CHMP4A,ATF6,XRCC4,ADAM23,PRPF4B,NDUFS1,DEPDC1,MECP2,SECISBP2,HMG20A,WWP2,JAKMIP1,SLC25A36,DNAJC8,AXIN2,CITED2,JMJD4,ANKRD37,KAT2A,TMEM126B,RABIF,ADSL,PACS1,BMS1,KCNQ1,ARSK,MACF1,KIF11,KLF6,COMMD4,SMAP2,FADD,SH3GLB1,MYO1F,CBX3,TMEM127,INF2,PPP1R11,DUSP11,DDX5,WDR62,TAF6,ESPL1,PURA,DDB1,DEF6,IPO4,FAM83G,UBL3,NAT9,PIGM,LYRM4,GPR132,UBE2Q1,PTP4A3,BRIX1,MRPL19,ZNF696,SF3B2,PCYOX1L,CDC42,SYNM,GOT2,JAZF1,HADHB,RPF2,SLC35C2,CNNM3,CARM1,SRPK2,WDR41,LARS,ZCCHC10,CCDC138,LRBA,TMEM216,SUMF2,KMT2C,OGFR,PRPSAP1,ASF1B,RPL37,MAN2A2,EIF4ENIF1,NIP7,U2SURP,MIA2,ATP6V0E1,PPP1R2,PM20D2,XPNPEP3,RGS2,LYAR,FAM89B,POLR2I,TRAFD1,SUGP2,GBA,SYVN1,DAPK3,ARHGAP15,MASTL,UAP1,NFIL3,FN3KRP,YWHAZ,CTSA,TMEM14A,TOB1,TSEN15,ADNP2,TCF12,PRKAB1,MDH2,SMARCA4,ORC1,RRN3,UBXN2A,IARS,CD3EAP,KIF14,EXOSC1,CS,CLTB,DNAL4,CSTF1,POU2AF1,UBQLN4,NXT1,HPDL,PGGT1B,SELPLG,SMU1,ATXN1,GLO1,OGDH,BICD2,CADM1,EDEM2,HERPUD2,TOLLIP,FANCE,MBD3,PDHX,RPS9,ALKBH6,SURF4,DUS3L,ARNTL,ANP32E,FKBP5,TMEM101,CCDC125,ABCA1,PDCD2L,GCLM,RAE1,NUP54,CHIC2,PAWR,MXD4,DCUN1D4,PIP4K2A,XPR1,FERMT3,KIF5B,KLHL20,SEC24C,RRBP1,ARHGEF2,LDLRAD3,STAT3,MYO5A,NIPAL3,AMPD2,TXNL1,PHF20L1,DCAF6,FAM49B,TMEM39A,ATP2C1,RFFL,COG1,RCOR1,PRMT2,TFEB,LEMD2,UPF1,ELMO1,ZC3H7B,DTX4,ZMIZ1,TERF1,HRAS,CCDC93,FGFR1OP,TMED7,PIGQ,AGPAT1,CNTROB,PPP1R16B,MIS12,GSDMB,TTC9C,PDS5B,NUP153,SENP1,PGAP2,TMEM115,PLEKHM3,DCUN1D5,PLEKHF2,BRMS1,PWWP2B,TRIM47,WDR11,AXIN1,SMG9,TRIM52,LONP2,NDUFV2,PHF23,CERK,SLC4A2,EZH1,ITGB5,LMNA,MCTS1,DDX56,EIF2S2,SLC38A5,FOXN2,CARS2,PRRC2A,C16orf72,RB1CC1,ZMYND11,PGS1,MYBL2,UHRF1BP1,SRSF5,MPG,MATR3,CYB5A,NCDN,POLR2J,SETD3,PTAR1,CNOT6,NDE1,EGLN1,ZNF207,ANKRD27,ABCA3,IVNS1ABP,RMI2,MON1B,TMEM97,NIT2,NUF2,ZNF267,TCF19,TMEM161B,KTN1,APP,PRKD3,CLUAP1,ATP2A2,UTP18,DUT,ANAPC7,RNF19A,FAM76B,CLN6,TMEM9,GCC1,RNF169,ADCY7,ATP6V1G1,ENPP4,RNPS1,CDCA2,FKBP3,GPR137,DDX17,CHCHD3,PEX5,CDC16,HIPK2,MBOAT1,TICAM1,PDXK,ZBTB11,TMBIM4,GMCL1,UBE4A,IL21R,ETS1,WRB,ZNF92,PNO1,CAPN2,ADD3,SUV39H2,TTLL12,TPCN1,TMX1,LYPLA2,HNRNPM,LDHB,PPP3CA,NUDT8,POLK,JTB,EMP3,MTMR12,ZP3,PDE3B,KIF18A,CCDC6,WNT5B,MAPK6,C4orf46,LY75,SLC25A19,RGL1,PSAP,WDR76,IGBP1,FAF1,SNAPIN,COX15,THOC1,AGRN,GNPDA1,GPBP1L1,PPP1R15B,CSNK2A1,EBNA1BP2,GIT2,BIRC2,ATPAF1,DLG5,ABL2,XRCC2,ZFYVE27,MCMBP,PTPRK,CDC37,METTL1,SP3,EXOSC6,HARS,GMFB,ESYT1,ANLN,RAB5B,RHEB,DPYSL3,TBC1D17,TIMM13,CDCA4,TONSL,NRM,NAGLU,ACTB,ZNF45,TMUB1,CTCF,ASAH1,DOCK11,CRLF3,ASXL2,LRRC14,NUS1,SLC27A4,AFF1,MDFIC,MAML1,CYTH1,NQO2,UTP15,EIF2AK1,EIF4G2,ZDHHC3,MOSPD3,ITPRIPL1,CDC27,SNAP23,TBPL1,PRMT7,KCTD7,NDUFA5,CYLD,UGP2,DYNLL1,COPE,HCFC1R1,ZADH2,GGPS1,RAD23A,PDK2,ATP6V0B,STRBP,DUS4L,MRPL34,PDCD2,SAP30L,SLC39A9,CLPTM1,RPL29,RPL35,BTG2,DNAJC9,MTMR6,FRAT2,NFATC2,KDM1B,ARL5B,USP36,CCDC127,MRPL2,ATP1A1,CLK3,PSMD3,MAFK,CEP55,NDUFA11,DNAJC17,ZNF436,NCOA1,SLC25A39,ZC3HC1,ZNF146,ATXN7L2,CDC40,GOLIM4,SMAP1,RRP15,DAP,GNE,SMC6,ARFIP2,NKRF,CHAC2,BZW2,WRNIP1,SS18L1,CENPM,PTGES3,CAMK2G,MLEC,ZNF202,PPWD1,FAM50B,RHOT2,NEU1,TPD52L2,GOLGA7,TWSG1,GLG1,PGRMC1,FAM126A,RPS6KC1,UBE2C,PPCS,NDUFB6,TMEM41B,ZDHHC8,PLXNA1,CCNB1,SLC20A1,COMMD6,ABHD14A,POLR3K,C14orf119,ASAP2,SNUPN,TFG,PLCL2,SEH1L,ATG9A,PBK,MKI67,DDX20,AMDHD2,SLC17A5,GALNT7,CCNF,FOXRED1,RBM47,PTER,WDR4,DHTKD1,TRAF5,HDAC2,PWWP2A,HSPH1,MAPRE1,CHTF18,ADO,KIF23,SLC35B1,NOTCH2,JMY,FKBP1A,SLC31A1,SNX18,ATIC,ATP6V0A2,PIKFYVE,RNF135,LPCAT1,EEF1D,TMED2,FTL,PHF10,DDX28,ZNF84,SIGMAR1,PIP4K2C,RIT1,PLEC,KDM3A,SF3A2,FAS,EPRS,ZNF777,TMEM54,QARS,PPP3R1,TCOF1,NRBP1,CABLES1,DNMT3A,RWDD1,CKLF,TRIP10,SF3B1,RPS6KA1,SUZ12,CAST,RAC1,GPR89A,OLA1,SNN,GNB2,FLAD1,APLP2,KDM2A,CDKN1B,TNPO2,TALDO1,GPX4,ATP13A1,RFC3,MAPRE2,ERF,CUL3,SLBP,H2AFV,POLG2,GAR1,PSMB9,DHX57,NSA2,HSPA4,MRPL55,JAK1,TBL3,SEL1L,H2AFX,KLHDC4,B4GALT3,PDCD11,ATMIN,POLQ,POU3F2,OTUD5,NCOR2,ANKRD13D,PKP4,SCAMP3,CDCA3,SLC25A12,BLM,TMCC3,GTF2F1,RPL17,CRAT,AHSA1,PRC1,UPF2,COPS7B,SLC38A10,CNOT6L,CNPY3,UBE2M,IFT46,TMEM160,TSHZ1,ZFP64,DENND4C,DENND1B,WDR18,RPL8,ILF3,LRRC1,RHOT1,MARK2,TSR2,ECH1,PRDX1,PLD3,NUCB1,FBXO21,GNA12,C1orf131,PRDX3,PFDN4,HNRNPH3,STX18,TFDP1,KHSRP,ASNA1,CPEB2,SSSCA1,BYSL,VPS29,S100PBP,MIB2,IER2,PTMS,NOP2,UBN1,DCAF15,NF1,ALKBH5,MOGS,TAF6L,MAPK14,BECN1,SNAPC4,RNF103,BCAT2,MBD4,C18orf32,METTL14,IMPAD1,ZNHIT6,RCSD1,PHTF1,SRI,KIF22,ZBTB22,NFU1,OGG1,TRIM14,ELOF1,COPS8,FYTTD1,TRIM8,RRM2,SOX4,ABHD5,CXXC4,UBTF,PAF1,UEVLD,SPATA2,PQBP1,IARS2,ATXN2L,GALNT10,STARD3NL,RPS15,PIGN,AGTRAP,CIB1,XPO7,SRRT,ZNF449,CAPZA1,GLTP,KIFAP3,BCL2,N4BP2,HP1BP3,THNSL1,ISG15,CAND1,GNAS,TSC1,RBM25,CDCA5,ZFP90,NANP,RBBP4,ZBTB24,SMARCD1,MBD1,WASF2,MMACHC,TOMM20,IFI27L1,GNPNAT1,MPHOSPH8,CHD1,MEAF6,C2orf68,CCDC50,AKAP8,PARL,RPN2,CHTOP,FAM3A,F2R,SCYL3,TMEM14C,ABI1,HTRA2,MOSPD1,RLIM,FAM172A,ZNF500,PSMB7,NLN,WIPF1,BOLA1,BUD13,NDUFB1,PEF1,EIF3G,BTBD1,TAB2,CHCHD1,TULP3,WDR59,CANT1,SCARB1,GAS2,USP11,SMURF1,PPP2R2D,TSPAN5,CDS2,MAGEH1,MRPL42,EYA1,CDK2AP2,MRPS26,LETMD1,KLF13,HDDC2,RGS1,MAN1A1,FBXO5,GART,TANK,BRD7,MRPL11,SAMD4B,ZDHHC18,GTF3C6,POLR3GL,WDR81,MEN1,ZNF407,MFN2,COX8A,ZRANB2,MBD6,SRSF3,ATP6V1C1,IDH3B,TATDN1,TSC2,LACTB2,CMTM6,RBM4,ZNF275,RPL23A,CDKN2C,USF1,MECR,AP1M1,UPRT,CRY2,ECD,RNF26,TIPARP,LRRC59,ANKRD9,RHBDD2,MGAT5,BAK1,ZNF559,RHOBTB3,GABPA,WBP1,NUTF2,ARF4,GINS4,KRIT1,BOLA3,AHNAK,RAD18,PDRG1,RNASEL,CHPF2,OAZ1,SMNDC1,PDCD4,NXT2,HIVEP3,KIAA0100,CLSPN,RHOC,DHX9,PDCD7,PSMD9,HAUS2,COPB2,CD59,TFAP4,RNFT1,RIMS3,MEGF8,FBXO7,EFTUD2,CPSF4,MRPL21,PHKG2,LUC7L2,SRSF11,EIF3L,MTA2,TYW1,USP10,ITM2A,SSR2,BCLAF1,MTX1,SFXN5,FNTA,PDLIM1,TXNDC16,TMEM159,MRPL3,ALS2,FAM72A,TRIM41,KARS,NQO1,POC1A,ANK3,PTTG1,TPX2,TBC1D13,DAZAP2,STMN1,C19orf48,REPS1,ABHD16A,FBXL6,SH3BP1,MTA1,UBA5,CLCN6,INTS12,C8orf59,RPRD1B,CGGBP1,CPNE1,SEC61B,POLR2L,FAM118B,GOPC,E2F3,CIRBP,RPL38,CRNKL1,PFKFB3,GORAB,RAB1A,GIGYF1,TMEM184C,PPP2CA,KIF2A,CCDC14,LSM6,RNF38,SNRPG,DMWD,USP13,ZFP91,TRMT6,IP6K2,WDR5,SLC25A43,IFT27,PMVK,NEIL2,RRP36,SRXN1,RPA2,PSMD2,CLIC4,PDCD10,CBWD2,COQ4,ITGB8,ARF5,ARHGEF1,FBXL19,GTF2H2,TTPAL,UTP20,MAGT1,GPS2,DBI,SSNA1,MRFAP1L1,CD81,TMEM131,WDR13,FANCI,PAPOLA,CREM,TET3,FANCL,GLIS2,IL6ST,INTS1,POP7,SLC44A1,MTPN,ASB6,PLK1,RPP25,CELSR2,SEPT9,RBX1,APH1A,RAD51AP1,CKAP2L,PSMG1,UBE2V1,EAF2,IL12RB1,KRTCAP2,LUC7L,LSG1,NECAP2,C1orf122,TRIM4,AGPAT2,CHD3,ZNF367,E2F4,PRPF4,KPNA2,BEND6,CLN3,DNAJC30,FAM208A,NGLY1,POT1,MYL12B,CCDC137,RMND5A,HJURP,PHB2,DNAJB2,FAM53C,NKD2,SDC2,KLC1,CDK13,ADCK5,COX4I1,DNAJB1,RAB6A,ARID1B,C1GALT1,MLX,UBE2Q2,CCP110,ZNF746,ARL6IP1,CTR9,NIPSNAP1,ABHD2,DCAF8,ACSL3,LDB1,MAP4K3,ARMC8,NMT2,IRF5,RPL36,HAUS8,MBIP,ORMDL2,COX7A2L,ZDHHC7,SIL1,FAM122A,UNC13C,BCCIP,SART1,TRAF7,NDUFAF2,TOR1AIP1,ZNF416,LAGE3,ZFYVE21,TM9SF3,RRAGC,ZNF121,OIP5,NRF1,WDR44,PIN1,EFCAB11,RPAP1,CABLES2,LMAN1,AHCYL1,TOP1MT,STRAP,SPSB3,ZNF583,SNX25,ARHGAP17,POLR2G,PPT1,NUP155,DCLRE1C,MRPS14,RHBDF2,SUGP1,RBL1,FASTK,STK38,AP1S1,SPRYD4,H3F3A,CHID1,SMAD4,RAD51D,SLC30A9,CMAS,UNK,NADSYN1,HMGN3,NCAPG,SCYL2,FZD6,HERC3,GTPBP3,CTSS,ORC3,RNLS,YTHDC1,ACP2,HMGN5,CSRP1,METTL5,ABCF2,TUFM,RANGAP1,PNPLA8,HAGH,API5,ZFR,SEC23IP,E2F1,TMEM219,USP20,RBPJ,PDCD6IP,MAX,LUZP1,GXYLT1,ADAM10,CXXC1,TSC22D3,AP3M2,CUL1,GYG1,NANS,OAT,MYEF2,ANKRD26,PA2G4,NOL11,FIZ1,ZNF200,MARCH2,SLC26A2,SRP72,KLF10,LACTB,CBFB,RFC2,RAB2B,MAP3K4,HHEX,LUC7L3,RPS14,MAP4,MRPL27,BTF3,PTPDC1,NMD3,CCDC59,PTOV1,COX5B,DNAJC5,SCOC,DHPS,POLR2K,ANKH,PRKAA1,C16orf87,VAV2,GSPT2,DLGAP4,PXMP2,PRPF39,PSEN1,ZNF79,PDXDC1,VPS25,NDUFS7,YY1AP1,C12orf10,FAM192A,RPN1,LHX8,ARPC5,ZNRF2,TPST1,DAPK1,PIK3IP1,CYC1,SOCS5,FDFT1,PIGT,EMB,WDR1,ZNF574,C1orf35,EXOSC9,ARID1A,PTTG1IP,C9orf40,FXR1,GOSR1,MAP2K2,TWISTNB,AKAP1,XRCC5,HMGN2,PI4K2A,CAT,SEC31A,DERL1,MTHFD2,HSPBP1,CEBPG,ARAP1,USP32,FAM83D,CABIN1,SMPD4,GPI,CYTIP,TP53RK,REPS2,RAB11B,UROD,SLC39A13,POMP,BCL2L1,NUDT19,DECR1,RALB,SIAH1,ADCY9,LPIN2,MRPS27,SOCS6,TTC3,RNASEH2A,CFL1,ANKLE2,CDC123,OAF,VDAC2,EDF1,EML4,ERC1,AMZ2,ANKZF1,RAD51C,ZNF282,DSN1,DDOST,HINT1,DGCR8,SAFB,HAGHL,FTSJ1,RWDD4,LMBR1,NCLN,BEND3,EYA2,DYNC1LI2,MANBA,SLC41A1,B4GALT5,FAM76A,TKT,CBLL1,ARGLU1,LANCL1,POFUT1,FAM8A1,HEATR5B,HLA-A,EBP,RFWD3,NDUFA2,FUT8,BTF3L4,PTPN11,MRPL54,FEM1B,RPL19,CNN2,NDUFA3,MTX2,MSH6,PDLIM2,LONRF3,RFXANK,FBXO9,GUF1,RPL32,ZHX1,NDUFS5,WDR91,GPR89B,HIGD2A,ZBED3,RORB,POLA2,ZNF76,MTX3,COPA,PHRF1,ABCB10,COMMD5,MAP1LC3B,DST,RAB35,SIVA1,GPATCH1,TCEA1,DRAM2,DEAF1,SNRNP200,LAP3,NCK1,VHL,SREK1,ARHGDIB,PITPNB,HSPB11,BRWD1,PPM1G,SH3GLB2,CRCP,BAZ1B,ACBD4,CAB39,STK11,CLU,CHEK2,ZSWIM3,TSTD2,MRPL13,CHPT1,DCAF5,CAPN1,UBE2D3,NSMCE4A,PPP1R12A,ZCCHC8,GORASP1,NACA,UBXN1,RPL15,PCSK7,THRAP3,QSOX2,TTF1,NUP205,PRPF18,CHKA,MED10,ZRANB1,MCPH1,SLC12A2,ATP6V0D1,CSNK1G3,CREG1,NUDT4,RPL6,VKORC1,SLTM,EVC2,KLHL15,SIAH2,SLC16A1,EHD4,SNRNP70,C11orf1,APOL2,N4BP2L2,SNX27,CHMP2A,CORO7,UCK2,PMS2,UCK1,CLCC1,EXT2,MXD1,USP5,HNRNPA2B1,SAP130,NVL,PPP6C,CYB5R1,ZNF770,EBAG9,RNF25,PCGF6,METTL2A,FAM72B,PON2,HPS5,STAT6,MAPK1,BRD9,TMEM33,NAT14,DNAJC2,TRIP12,SHPRH,SCYL1,VPS45,GFM2,SPPL2A,FASTKD3,FGFR3,MZT2A,PPIG,ZDHHC13,TMEM99,H2AFY,ATG13,NDUFS8,ERI3,FBL,FRMD8,SLC35A1,MICAL3,TGFB1,B3GALT6,ELOVL5,HEMK1,TIMMDC1,HELB,PSPC1,MIER1,SCFD2,NDRG3,CDK11A,MTMR3,ACAT1,CENPT,PLOD3,RAB3IL1,RAB14,ADD1,MRPS15,KDM4A,XIAP,DHX8,GLUD1,ANKRD23,PABPC4,CALM2,CDK5,PSMD1,NEK6,NSRP1,RABGAP1L,SRSF4,FNIP2,KCNAB2,PCBP2,MLST8,PLK3,ZNF672,MRPL43,HSDL1,TOPORS,MCL1,SMC2,PPFIA3,ICMT,SLC50A1,STOML2,LIMK1,ZNF689,PRDX5,ATE1,MLYCD,ATP6V0C,ST3GAL2,FBXL3,TFDP2,E2F2,PFKP,AAAS,DDX42,SSRP1,MRPL9,MRPS2,STRN4,TOP2B,ZNRF3,TMED3,DDRGK1,RAVER2,GNS,INTS7,INPP5A,MCM5,PHF14,ZNF326,NAGPA,TIMM8B,ETV3,DHX29,TEX10,MAN1B1,RPS10,CBFA2T2,ABCF1,RHOB,LRRC14B,DTWD1,PTPRF,SCARB2,OSBPL11,CCDC86,DUSP3,SLAIN1,MDH1,HEXA,RNF139,SNX14,ZNF296,TRERF1,UBR2,CHD1L,ACTR3,WDTC1,MYH9,CREBL2,NIPA2,PRKACA,SAFB2,ANKIB1,STAM,ARL6IP6,RAB21,SP100,ZKSCAN1,DDA1,NUP107,ANKRD13C,MAVS,CEP63,TMEM136,RBM15,ATF2,DCTN1,SHOC2,PSRC1,MAP4K4,WBP2,ATP6V0A1,NDUFA7,DNAJA1,TAZ,TAF2,SEC61A1,WDR7,RPLP1,CBLN2,RBMS1,FUS,GEN1,LRP8,COIL,LRCH1,GALK1,ZNF786,RPS2,SESTD1,TRAK1,JMJD6,SIKE1,AKT1S1,KRI1,FBXO3,ERH,GATC,PPP1R8,PRDM4,GTSE1,GEMIN6,DCP1A,SGCB,S100A6,IMPA2,NUDC,PDPK1,TK1,GUK1,TNFAIP3,GALC,ZNF512,KIAA0930,MRPS10,DDX39A,RPA1,ZNF862,ZNF180,KEAP1,POLE,TATDN2,PITX1,CAPN7,LRPPRC,PML,HMGB2,USF2,ANAPC4,SRM,DDX47,MCCC1,CDC42SE2,S1PR2,CDIPT,SEC16A,SSR1,LIN9,PCNA,ZNF639,PIK3R2,ETV6,PPCDC,TXLNA,FAM86C1,MYBL1,MRPL32,CCAR1,ABCC5,PBXIP1,TLK1,MRPL12,EZR,LNX2,LRP5,BRCA1,PRKRA,STX16,EPB41,OPTN,SEPT1,SOCS4,QRSL1,GLCCI1,NUDT11,GEMIN7,SEPHS2,LZTR1,RACGAP1,PPP3CB,B4GALT4,RLF,RAPGEF6,SNRNP25,RB1,VASP,MED8,VMP1,PPIL2,MEA1,TIMELESS,AHDC1,ALDH18A1,TMEM8A,ABCC1,PREB,TRAPPC9,AACS,MEMO1,KRAS,RTF1,UBE4B,NFATC2IP,LY6E,ARPC1A,ZNF174,PSMC4,GOLGA4,SYNCRIP,PALB2,PRPS2,NIPA1,TIGD2,RNF114,FOXM1,MRPL39,XAB2,SUMO2,DUSP22,COMMD8,RPL11,CSDE1,MDM2,CORO1A,MINPP1,METTL9,POC5,DVL2,GM2A,PSMA8,COQ10B,CPOX,TIGD5,SLC26A6,CYP20A1,PRPF3,TXNL4A,RPSA,SRSF1,DNAJC10,ZNF700,SCAP,PLEKHG4B,TIMM17A,FAU,LTA4H,AP2S1,USP53,INTS2,CTDP1,MIF4GD,CDT1,ARID5A,SUMF1,GGA2,AP3S1,CSNK1A1,RMI1,TFRC,PTPN2,STARD9,IRF4,GSTK1,NDUFV1,SLC1A4,CWC27,SLC35B4,DDX31,ABCD1,RPAP3,CNTN5,SNX2,ZMYM5,CCDC34,CHCHD6,BSDC1,KPNA4,CDKN2AIPNL,FBXO41,BIRC5,TFE3,SNAP29,CDCA7L,PKD2,ACADM,CHMP7,SAT2,GCSH,ZNF496,TMEM109,TAP1,NHLRC3,IKBIP,EIF1B,ELMOD2,KIFC1,DBNDD1,RNASEK,CDC25B,PRADC1,DNMT1,NOL12,ORAI2,AKT2,NOL8,GNG7,AURKB,MCFD2,SLC25A5,ZFAND5,MAK16,STT3A,TMED10,PSMD8,EIF2D,ITGB1,PTPN7,UQCRH,RRS1,ARRB2,RTN3,SVIP,DDX58,WSB2,PPIB,MUT,GMFG,HLA-E,NDUFA4,MAN2B1,METTL3,CFLAR,NDUFS4,RNF121,MEX3C,KLF16,HDAC7,DAD1,BDH1,PCYT2,GNAI2,ANKHD1,MORC3,TERF2,KCTD20,SEPT8,DCTD,TOMM40,ADSS,SERTAD2,SERF2,ZFP92,NSF,DCK,ERGIC3,ACLY,LPCAT4,VCPIP1,YY1,PPP6R3,PPP6R2,MAP3K5,RNF14,CDK2,ZC3HAV1,ZBTB37,URB2,EIF3D,MAGED1,KLHL18,ADPGK,SLC25A44,AP1B1,SDHA,PAIP2,PHC2,CRKL,TERF2IP,MOAP1,CYHR1,ZNF75D,SHC1,UCHL5,NAA35,TMBIM1,CCT2,CDKN2AIP,MKLN1,HMGN4,GALK2,CDC23,SHCBP1,AP4E1,PRDM11,VEZF1,PPP2R5A,ACYP1,STAT1,PPA2,TRIM32,RHEBL1,C1orf112,TCF3,MRI1,BRAP,AGPAT3,MYNN,SDF2L1,SPR,RAB11A,REEP5,FOXO3,MAD2L2,CCDC28A,PIP5K1C,RBM17,MAT2B,PTEN,CENPJ,TAGLN2,OSTC,CREB1,PACS2,NCOA2,SMC4,RNASEH2C,NEK7,NET1,PARP4,TBRG4,ANAPC2,RPL27A,YIF1A,SGSH,HGS,TTLL4,SLC38A7,MFAP1,CCDC69,BRWD3,ESYT2,SKA3,NPHP4,UBE2E2,PLXNC1,TMEM184B,ST13,DNAJC24,ZNF107,KIF2C,SLC29A1,AGFG1,SIRT2,FKBP2,USP48,SNRPD3,UBQLN2,CUTC,EDC3,UBLCP1,ZNF804A,RAP1A,THADA,EIF4A3,AP3S2,ATG3,DPYSL2,PPP1R12C,AKR1B1,NDUFB9,JOSD1,RP2,TTC4,TECR,ARID4A,FGFR1OP2,TIMM50,TDP1,DPM1,FOPNL,SLC16A7,WDR82,SLC25A22,STK17B,DHX15,CHAF1A,GEMIN5,COPS6,SASS6,RPS26,PSMC1,SLC12A7,TBC1D12,TM9SF4,ZNF768,UFC1,MED13L,TIA1,EPHX2,PITHD1,RHBDD1,NFATC3,BANF1,ZNF335,BUD31,YBX1,KNTC1,ACAD8,UBE3C,ZNF189,ALDH9A1,KDELR1,TSTA3,CIC,OXR1,PSMA1,SEPT7,NAP1L1,ODF2,EXOC4,KIAA1328,NUP62,PITPNA,NAA20,PTDSS1,MZT2B,PDSS2,C7orf26,TMEM106C,IMMT,ASH1L,CHERP,WDYHV1,PLAGL2,CHKB,IRF3,TWF2,PAIP1,ANKRD28,FARSA,SAR1A,SCAMP4,APOOL,PDIA6,ACSL5,TOR1AIP2,AZI2,GFER,RAD54B,TMEM41A,DAP3,ZNF317,GADD45B,AKNA,REEP4,CBX4,MIF,KIF3B,GOLPH3L,SH2D3A,CASP6,TOR3A,SRGN,DBF4,MFSD10,SAC3D1,CTNNBL1,YIF1B,CLDND1,TTC17,SLC25A1,PAQR6,CSNK1G2,TELO2,ADAM17,HMGN1,NASP,ASPM,PRKAR1B,SYMPK,TARS,SNRPA,MAPK3,HSPA1B,HLA-B,ATAD2,PLAA,ZNF330,OSBPL8,KBTBD7,PREPL |
| 1.478e-09 | -20.33 | GEORGES_TARGETS_OF_MIR192_AND_MIR215 | MSigDB lists | GEORGES_TARGETS_OF_MIR192_AND_MIR215 | 814 | 186 | 17377 | 2626 |
POLA2,UBL3,FGFR1OP,PIGM,ZBTB10,XIAP,AP3M2,ABCB10,NHLRC3,MAP1LC3B,CMTM6,PABPC4,FANCI,MIS12,PRNP,KIFC1,LIN9,DST,DLG5,IL6ST,PHTF1,ZNF200,FBXW2,SLC26A2,PRADC1,RNF26,SENP1,USP34,NOL12,TDP1,DEAF1,LARS,RHOBTB3,KLF10,SLC16A7,MRPL43,MKI67,KIF15,CKAP2L,BRCA1,SMC2,PITPNB,EAF2,ANLN,STK17B,PLEKHF2,PRIM1,MAN2A2,CDCA4,TMED10,ITGB1,RNASEL,ZSWIM3,ZNF45,SASS6,GLCCI1,CHPT1,MRPL13,ZMAT3,FUBP1,RECQL,PPP1R12A,HJURP,CLSPN,CCZ1,CENPF,RAB23,KIF23,CTCF,RACGAP1,PMF1,CRLF3,PARN,ATG4A,DTL,RB1,ZNF449,ARL6IP1,BCL2,N4BP2,ALDH9A1,PHF10,IFRD1,ELL2,EMB,ZMYND11,UHRF1BP1,APPL1,PHF6,GNAS,SYNCRIP,NSF,KLHL15,PRPS2,FAM83D,NAA20,RUFY3,NDE1,NIPA1,CDKN2A,CKLF,TOR1AIP1,C5orf30,PLAGL2,UCK1,CREBL2,NUF2,ORC1,ZNF267,C2orf49,ZADH2,STAM,KIAA1147,EPM2A,MOAP1,PHC2,MRPL50,PRKD3,KIF14,EFCAB11,ZNF226,TARDBP,METTL9,TMEM136,LMAN1,CLN6,SAP30,ATP6V1G1,ENPP4,SLC39A9,PSRC1,ERMP1,PPP1R18,KDM1B,RAB1A,RAD54B,DSN1,CERS6,CCDC14,CEP55,GEN1,LRP8,PPP2R2D,POLQ,MCM10,PKP4,MZT1,DEPDC1,C1orf112,TOR3A,PAWR,NKRF,BLM,RMI1,DNAJB9,FBXO5,FBXO3,KIF5B,RFWD3,SLC1A4,PRDM4,SLC35B4,NAA50,BTF3L4,DCP1A,SGCB,MED22,MSH6,SMC4,RPAP3,ELOVL5,ASPM,MTMR12,OTUD3,BORA,MACF1,KIF18A,NEK1,ATAD2,OSBPL8,NEIL3,CCZ1B,FAM126A,WDR76,SPCS3,PURA |
| 1.480e-09 | -20.33 | BUYTAERT_PHOTODYNAMIC_THERAPY_STRESS_UP | MSigDB lists | BUYTAERT_PHOTODYNAMIC_THERAPY_STRESS_UP | 771 | 178 | 17377 | 2626 |
CCDC93,UBL3,HECA,PNISR,KDM4A,GNPDA1,GPBP1L1,XIAP,CSNK2A1,MAP1LC3B,RNF103,DST,ABL2,CDC42,AP3S2,RP2,EIF5,TIPARP,ABCC5,RYBP,PLK3,NRAS,KLF10,BAZ2A,GABPA,GMFB,SREK1,TOPORS,SLC17A5,LUC7L,STK17B,RAB22A,EIF3A,OPTN,ABHD5,ANKRD10,TBC1D17,BRWD1,BRD2,AXIN1,CLU,TFDP2,PDCD4,NUMB,SLC12A7,RMND5A,HSPH1,FAM53C,DNAJB2,MUM1,DLGAP4,LAMTOR3,MED13L,MEF2A,RAB6A,DNAJB1,EZH1,RGS2,RLF,PSEN1,WDR48,CHKA,ATP6V0A2,MORC3,SRSF11,FTL,ZNF84,RB1CC1,NUDT4,MAP4K3,RIT1,CBFA2T2,FXR1,KDM3A,RHOB,PI4K2A,TSC1,SLCO4A1,MTHFD2,FNTA,RBM25,GOLGA2,ETS2,CSNK1G1,SNAP23,NFIL3,CEBPG,TMEM159,MYO9A,TOB1,ZC3HAV1,N4BP2L2,ADNP2,ATXN3,UBR2,PLAGL2,RRAGC,ATP6V1B2,SNN,GGPS1,STAM,NRF1,ZNF473,KDM2A,GMEB1,CLCN6,TP53BP2,CHTOP,ATF2,GCC1,ABI1,SPSB3,ADCY7,PPIF,CDKN2AIP,BRD4,MKLN1,COQ10B,RAB7A,CUL3,PFKFB3,DNAJA1,MEF2D,AZI2,SERP1,USP36,RAD54B,ZNF282,HSPA4,RNF38,TICAM1,NCOA1,SMURF1,ABCA1,SMAD4,GCLM,GOLPH3L,BRAP,CHIC2,BTN3A1,CBLL1,JMJD6,MXD4,IP6K2,CCDC28A,DNAJB9,SLC25A36,SLC1A4,CENPJ,AHSA1,PRDM4,PELO,TANK,DCP1A,ARHGEF2,FEM1B,UPF2,TTC17,MAP3K14,CITED2,ADAM17,TMEM39A,ZNF202,DENND4C,ZMYM5,KLF6,TTC33,BSDC1,NEU1,MTMR3,SLC38A7,MEGF9,RGL1,ZMIZ1,ATP6V1C1,RPS6KC1,HIPK3,IFI16 |
| 1.486e-09 | -20.33 | RPS7 (ribosomal protein S7) | protein interactions | 6201 | 180 | 62 | 17029 | 2761 |
RPS15,RPS2,CYLD,NOP2,RPLP2,LAMTOR3,RPL15,CUL1,JMJD6,BRIX1,PNO1,LMNA,RPL11,RPL23A,KRR1,HNRNPA2B1,RPA2,MDM2,NEK6,HUWE1,AHSA1,PIK3R2,BUD31,RPL19,UPF2,TARDBP,FBL,HNRNPM,ABCC1,RPL35,DDX24,RPS10,RPL6,CUL3,RPL8,RPL38,RPS24,BRCA1,EIF2A,MCM2,RPL27A,RPS9,RPSA,PSMC4,RPA1,RPL36,DDX23,CAND1,UTP20,TRIM26,RPS14,RPLP1,RRS1,FAU,CDK2,ARRB2,HNRNPDL,RPS26,POT1,TERF1,DDB1,CDKN2A |
| 1.490e-09 | -20.32 | SRPK1 (SRSF protein kinase 1) | protein interactions | 6732 | 239 | 76 | 17029 | 2761 |
SART1,COX15,UBE2E2,DDX47,NOP2,CHERP,RBM8A,DHX8,USP39,MAPK14,PCBP1,APP,TRIM65,KRR1,RBM23,EIF4A3,NSRP1,SRSF4,TRA2B,TARDBP,FAM76B,AHCYL1,CHTOP,SRPK2,MRPL43,RNPS1,CUL3,SREK1,LUC7L,FKBP3,SRSF1,RPL37,DGCR8,LIMK1,SAFB,LUC7L3,RPS14,PPM1G,KPNA2,FUS,CHEK2,SSRP1,NXT2,EWSR1,NSMCE4A,SRSF6,FLOT1,DHX9,ASAH1,HMGN3,ARGLU1,THRAP3,DNAJC8,AHSA1,PPIG,H2AFY,PABPC1,HNRNPM,LUC7L2,PDPK1,YTHDC1,STAU1,ZMYND11,ILF3,C1orf35,BCLAF1,SRSF5,TFEB,CAND1,CACNB1,SETD3,DDX5,ZRANB2,SRSF3,SNRNP70,IFI16 |
| 1.491e-09 | -20.32 | GSE22611_UNSTIM_VS_2H_MDP_STIM_MUTANT_NOD2_TRANSDUCED_HEK293T_CELL_DN | MSigDB lists | GSE22611_UNSTIM_VS_2H_MDP_STIM_MUTANT_NOD2_TRANSDUCED_HEK293T_CELL_DN | 183 | 60 | 17377 | 2626 |
TCF12,SNX27,KARS,PIGQ,UBE2Q1,CUL1,AGPAT3,NOTCH2,NHLRC3,EIF2AK4,CSNK1A1,COPG2,APP,CDC73,SPAG5,EBP,FKBP1A,VAV1,MED10,TNPO3,AP2B1,UPF2,AHCY,TAF5L,LPCAT1,CTDSP2,CDC37,SRP72,MAPRE2,PRIM2,GABPA,PSMB7,GORASP2,GLO1,PRPF3,UBE4B,SLC25A5,EML4,PHF6,PI4K2A,TAF2,TSC1,GNA12,SEC23IP,TTC13,NSF,TATDN2,TPP2,OAZ2,ARNTL,GLG1,VCPIP1,BAZ1B,CABIN1,NDE1,TSPAN5,LONP2,MRPL3,BYSL,CSNK1D |
| 1.491e-09 | -20.32 | GSE24634_TREG_VS_TCONV_POST_DAY7_IL4_CONVERSION_UP | MSigDB lists | GSE24634_TREG_VS_TCONV_POST_DAY7_IL4_CONVERSION_UP | 183 | 60 | 17377 | 2626 |
TMEM106C,GALK1,PKP4,HNRNPAB,HJURP,ANXA6,C1orf112,CDT1,PTTG1,CENPF,TPX2,CDCA8,PXMP2,KIF2C,BLM,CCNB1,PPP1R16B,FANCI,SPAG5,CREM,DTL,IRF4,CCNA2,DUT,PPIL2,FUT8,PPCDC,PRC1,KIF22,KNTC1,CDC25B,CORO1A,RNASEH2A,CENPM,MRPL11,GINS1,TK1,PSRC1,KIF15,TOP3A,MYBL2,WDHD1,SLBP,RRM2,ITM2A,NUSAP1,AURKB,NDUFA7,MCM2,KIF11,TARS,SLCO4A1,ATAD2,BIRC5,CEP55,TFDP1,H2AFX,WDR76,CCNB2,UBE2C |
| 1.493e-09 | -20.32 | GSE27241_WT_VS_RORGT_KO_TH17_POLARIZED_CD4_TCELL_UP | MSigDB lists | GSE27241_WT_VS_RORGT_KO_TH17_POLARIZED_CD4_TCELL_UP | 153 | 53 | 17377 | 2626 |
MCM10,SEC61G,CHTF18,SUMO2,CENPF,CDCA8,TPX2,KIF23,RACGAP1,STMN1,NUP205,SPAG5,RFWD3,CCNA2,SHC1,MEX3C,CENPJ,PPIG,KIF14,JAZF1,XRCC2,PRC1,GTSE1,KIF22,KNTC1,CDC25B,RNF26,MYBL1,TACC3,PLK1,ASPM,MKI67,KIF15,CKAP2L,CDC6,CDCA2,SMC2,BRCA1,CCNF,ANLN,H2AFV,KIF11,RPSA,RAD54B,AKAP1,ATAD2,KIF18B,POLE,RBL1,NEIL3,FAF1,POLQ,FUBP1 |
| 1.503e-09 | -20.32 | phosphorus metabolic process | biological process | GO:0006793 | 2148 | 422 | 17256 | 2622 |
RAB14,FGFR1OP,PPCS,NDUFB6,ADAM10,MAP3K7CL,PIGQ,HEXB,AGPAT1,CUL1,NANS,CCNB1,SLC20A1,PARK7,EEF2K,CDK5,PSMD1,NEK6,RAB4A,UPRT,SUCLG2,FNIP2,SLC26A2,MAST2,CDC25B,KCNAB2,PLK3,PGAP2,NRAS,AKT2,PBK,AURKB,AMDHD2,STOML2,MAP3K4,MKNK1,SMAD2,RPS27A,PSMD8,LIMK1,AXIN1,PTPN7,COX5A,MLYCD,DHTKD1,UQCRH,RNASEL,PTPDC1,SMAD1,PFKP,COX5B,NDUFV2,CLSPN,GMFG,TRIO,PRKAA1,RRM1,RAB23,CERK,NDUFA4,CYCS,EIF2AK4,PSMD9,NDUFS7,NDUFS4,PDXP,INPP5A,ATIC,PPP4R1,CTPS1,MSH2,DAPK1,TPST1,PIGG,ATP6V0A2,PCYT2,CYC1,PIKFYVE,LPCAT1,PHKG2,PPA1,MORC3,FDFT1,PIGT,COQ8A,MAPKAPK3,PGS1,PIP4K2C,DCTD,PKM,MAP2K2,PSMB3,PI4K2A,ADSS,PTPRF,DUSP3,CSK,CSNK1G1,DCK,ACLY,PPP3R1,LPCAT4,MDH1,SAMD8,SMPD4,GPI,MAP3K5,PLPP6,CDK2,NRBP1,ACSF2,NUDT3,KARS,TP53RK,RPS6KA1,RAF1,RAC1,OLA1,STARD7,SLC35B2,EFL1,ADPGK,PRKACA,LCLAT1,CPNE3,SDHA,APP,FLAD1,CRKL,PRKD3,CCNA2,SHC1,MTMR4,DUT,ADCY9,LPIN2,TALDO1,GPD1L,RPRD1B,CDK12,ILKAP,CFL1,ADCY7,GPX4,CPNE1,ULK3,MAP4K4,TAOK1,CUL3,ATP6V0A1,PFKFB3,GALK2,PKMYT1,NDUFA7,TAZ,PSMB9,ERC1,TRIM28,PPP2CA,JAK1,HINT1,PPP2R5A,ACYP1,GUCY1B1,NT5C3B,HIPK2,PPA2,MBOAT1,PDXK,PPP5C,EYA2,CSNK1D,PRPF4B,GALK1,NDUFS1,MECP2,CCM2,TKT,BRAP,AGPAT3,ABHD14B,ATP5F1B,IP6K2,PMVK,PLPP5,NEIL2,PIP5K1C,PPP1R3B,CCNK,ERH,PSMD2,NDUFA2,NDUFB4,PTEN,FUT8,PTPN11,CREB1,MAP3K14,NDUFA3,GTF2H2,IMPA2,SPTAN1,LDHB,PDPK1,PPP3CA,TK1,GUK1,NEK7,ILF3,LDHA,ADSL,TBRG4,MTMR12,PDE3B,MARK2,GPS2,ATP5MC3,PARG,DBI,MAPK6,PML,NAXE,DUSP11,NDUFS5,PARP10,CCNC,PIGM,COX15,GNPDA1,NF1,UQCR10,PPP1R15B,HMGXB3,CSNK2A1,PTP4A3,CDIPT,RUFY1,MAPK14,ATP5PF,UBLCP1,MBD4,ABL2,CDC42,NT5DC1,IMPAD1,PIK3R2,SLC44A1,HADHB,PPCDC,NDUFB9,TECR,OGG1,FGFR1OP2,TIMM50,PTPRK,CDC37,SRPK2,PLK1,PTPN18,DPM1,RBX1,NCK1,TLK1,GMFB,RRM2,UBE2V1,PRKRA,PRPSAP1,STK17B,MPC1,ABHD5,AGPAT2,PPM1G,CAB39,BAZ1B,STK11,CHEK2,ROCK1,CLN3,CHPT1,NUDT11,PSMC1,SEPHS2,PIGN,PPP1R12A,LAMTOR3,MEF2A,COX4I1,ADCK5,CDK13,PPP3CB,EPHX2,CHKA,NUS1,TIGAR,PYURF,BCL2,MDFIC,MAML1,ALDH18A1,HDHD2,N4BP2,CSNK1G3,NTPCR,TSTA3,NUDT4,ACSL3,PSMA1,KRAS,MAP4K3,EIF2AK1,EIF2A,STYXL1,DAPK3,MASTL,PSMC4,MBIP,UAP1,PRPS2,COX7A2L,TBPL1,FN3KRP,DNPH1,ATP5F1A,NANP,NIPSNAP2,PTDSS1,NDUFA5,PRKAB1,SUCLG1,UGP2,GNPNAT1,MDH2,UCK2,ZFYVE21,UCK1,CHKB,ATP6V1B2,LYN,GGPS1,DUSP22,VAV1,PDK2,PSMA6,PPP6C,MINPP1,ABI1,CTDSP2,SCYL3,ACSL5,CGAS,PPT1,PSMA8,PSMB7,MTMR6,OGDH,NDUFB1,TOLLIP,PDHX,ATP1A1,TAB2,CLK3,FASTK,STK38,PSMD3,NDUFA11,MAPK1,PPP2R2D,CTDP1,NADSYN1,CDS2,SH2D3A,EYA1,SCYL1,GNE,ARF1,CDK11B,CSNK1A1,SCYL2,PIP4K2A,HDDC2,PTPN2,FASTKD3,FGFR3,NDUFV1,GART,GRK2,NDUFS8,STAT3,CAMK2G,RNLS,SLC25A1,AMPD2,TGFB1,ELOVL5,CSNK1G2,RHOA,RPRD1A,ACP2,PRKDC,PRKAR1B,NADK2,PNPLA8,MEN1,ATP5MF,CDK11A,MAPK3,HSPA1B,MTMR3,NEK1,PLAA,BIRC5,OSBPL8,COX8A,KBTBD7,IMPDH1,ACAT1,FAM126A,RPS6KC1,PGAM1,HRAS,HIPK3 |
| 1.519e-09 | -20.30 | SRSF9 (serine and arginine rich splicing factor 9) | protein interactions | 8683 | 77 | 35 | 17029 | 2761 |
EWSR1,SUZ12,SRSF6,HABP4,MRPS26,ITGB5,APP,LMNA,GTF2F1,SF3B2,HNRNPA2B1,VASP,EIF4A3,TRA2B,YBX1,SRPK2,SRSF11,CUL3,SREK1,BCLAF1,MATR3,SF3A2,GINS4,CAND1,SRSF1,HNRNPR,SAFB,DUSP11,SRSF3,FUS,SNRNP70,NKAPD1,HNRNPDL,HDAC2,DDB1 |
| 1.524e-09 | -20.30 | SONG_TARGETS_OF_IE86_CMV_PROTEIN | MSigDB lists | SONG_TARGETS_OF_IE86_CMV_PROTEIN | 57 | 28 | 17377 | 2626 |
TMEM106C,RFC3,TK1,NASP,FOXM1,CDT1,PTTG1,MYBL2,RRM1,TPX2,DNAJC9,SLC29A1,BLM,MCM2,KIF11,RFC2,RPA1,DDX23,FLAD1,RAD51C,PCNA,DCK,MCM5,H2AFX,E2F1,MSH2,HMGB2,DDX52 |
| 1.524e-09 | -20.30 | GO_SPINDLE_MICROTUBULE | MSigDB lists | GO_SPINDLE_MICROTUBULE | 57 | 28 | 17377 | 2626 |
PLK1,KIF3B,SKA3,PSRC1,BIRC3,KLHL21,PARP4,CUL3,XIAP,NUSAP1,AURKB,KIF11,RAB11A,BIRC2,HAUS2,NEIL2,SPAG5,KIF2A,CALM2,CDC16,KIF18A,CDC27,KIF18B,BIRC5,PRC1,KIFAP3,KNTC1,CSNK1D |
| 1.537e-09 | -20.29 | MORF_PCNA | MSigDB lists | MORF_PCNA | 78 | 34 | 17377 | 2626 |
KARS,H2AFZ,HNRNPAB,CHERP,CTCF,CYCS,PARK7,HNRNPA2B1,ERH,PCNA,BANF1,MSH2,FBL,MSH6,HNRNPM,CCT2,HMGN1,POLR2I,SNRNP200,PSMB7,TUFM,AURKB,MCM2,EIF4H,TRIM28,CBX3,SRSF1,HSPB11,SYNCRIP,RBMX,PSMD8,PPM1G,SNRPG,SRSF3 |
| 1.541e-09 | -20.29 | protein-containing complex localization | biological process | GO:0031503 | 231 | 71 | 17256 | 2622 |
EXOC3,NDC1,NUP188,SARNP,THOC1,DYNLL1,RBM8A,ALKBH5,AGFG1,HNRNPA2B1,CLUAP1,RAB8A,NUP210,EIF4A3,SRSF4,NUP107,DNM2,AP2B1,NUP153,CHTOP,ZC3H3,SEH1L,FYTTD1,NXT1,MIOS,POLR2D,RNPS1,SLBP,EZR,NUP155,RPSA,SRSF1,HHEX,HSPB11,GRIPAP1,RRS1,NMD3,AAAS,RPS15,KIF3B,CDC40,MZT1,KLHL21,RAE1,SRSF6,NUP54,IFT27,RAB11A,NUP205,KIF5B,UPF2,KIFAP3,GLE1,CPSF4,NUP85,IFT46,EIF5A,SRSF11,SRSF5,DDX39A,SYMPK,BBS12,TSC1,PCM1,UPF1,BIRC5,NUP62,SSNA1,SRSF3,NUP58,SNAPIN |
| 1.580e-09 | -20.27 | GSE369_PRE_VS_POST_IL6_INJECTION_SOCS3_KO_LIVER_DN | MSigDB lists | GSE369_PRE_VS_POST_IL6_INJECTION_SOCS3_KO_LIVER_DN | 192 | 62 | 17377 | 2626 |
RHOG,SART1,LZTR1,PLXNC1,MUT,TSC2,AGRN,RAB11B,GNPDA1,PRKCSH,DAP,PCSK7,ARFIP2,SLC4A2,MAN2B1,MYO9B,PMF1,SNN,PIP5K1C,FLAD1,VAV1,ZNF428,RB1,MCM5,MEGF8,PPIL2,RAB4A,MEA1,FAM89B,AP2B1,TECR,ZNF710,FAM3A,KCNAB2,SLC25A1,NAGPA,CLPTM1,TIMP2,MLEC,WBP2,ATP6V0A1,PFKFB3,RANGAP1,MAP2K2,TRIM28,MAPK3,MYO1F,UBTF,NUCB1,PLD3,SGSH,POLE,TFE3,ERGIC3,NAGLU,ARAP1,ATP6V0C,CTSA,ARRB2,HEXA,TERF1,DDB1 |
| 1.619e-09 | -20.24 | SART3 (squamous cell carcinoma antigen recognized by T cells 3) | protein interactions | 9733 | 160 | 57 | 17029 | 2761 |
RPS15,DDX47,NOP2,RRP15,RPLP2,CAST,SF3B1,DHX9,OLA1,USP39,THRAP3,BRIX1,RUFY1,CMSS1,IARS,RPL17,ZNF746,POP7,RPF2,YBX1,DDX31,RPL19,ECD,FTSJ3,HP1BP3,NOL12,CDKN2AIP,DDX24,SNRPB,RPL6,ZNF574,GTPBP4,RNPS1,CUL3,LSM8,DNAJC9,BCLAF1,PRPF3,BRCA1,RAB1A,PSMB3,CENPU,DHX57,CAND1,NSA2,RPL32,LSM6,LRPPRC,PRPF4,KPNA2,RBPJ,SNRPG,CFAP20,CDK2,COIL,NRBP1,IFI16 |
| 1.622e-09 | -20.24 | GSE37416_CTRL_VS_12H_F_TULARENSIS_LVS_NEUTROPHIL_UP | MSigDB lists | GSE37416_CTRL_VS_12H_F_TULARENSIS_LVS_NEUTROPHIL_UP | 179 | 59 | 17377 | 2626 |
WASF2,TRIM41,H2AFZ,ADD1,TMX4,CCM2,SDC2,MED13L,GMCL1,HAUS4,TBC1D13,ATG2B,CRLF3,LCLAT1,RMI1,FAM8A1,MAT2B,NFATC3,PCNA,ADD3,CTSS,SNX18,ZNRF2,RABGAP1L,TBC1D14,PPP6C,UPF2,UBE3C,MAP3K14,STRAP,MYO5A,ABCC5,CLPTM1,DDX28,ORAI2,TACC1,KIAA0040,WDR1,SELPLG,CUL3,CAMSAP1,FRAT2,TOPORS,UBE4B,BICD2,PDE3B,STK17B,SMAP2,SOCS7,EPB41,EIF3K,HHEX,WAS,CCDC69,LY75,GALNT10,MAP3K5,ZMAT3,RNF114 |
| 1.622e-09 | -20.24 | GSE23505_IL6_IL1_VS_IL6_IL1_TGFB_TREATED_CD4_TCELL_DN | MSigDB lists | GSE23505_IL6_IL1_VS_IL6_IL1_TGFB_TREATED_CD4_TCELL_DN | 179 | 59 | 17377 | 2626 |
TMEM106C,CCDC93,PPIB,CHMP2A,COX15,MUT,NQO1,DYNLL1,MDH2,CDK2AP2,MCCC1,LAMTOR3,CLCC1,DNAJB1,MXD4,ORC1,LYRM2,HMG20A,PARK7,HOMER1,NDUFV1,PHF14,MRPL34,AHCY,FRMD8,TMEM14C,LYPLA2,NIPSNAP1,TMEM160,ADCY7,GTF3C6,TK1,ERMP1,POLR2I,DNAJC9,NDUFA7,VKORC1,MRPS14,FAS,NEK1,POLE,POLR2J,ACYP1,PRDX5,EXOC4,APPL2,NDUFS5,GPI,RGL1,TMEM14A,CD81,PDSS2,RPS26,ANAPC4,FAF1,VPS29,PDCD4,SSRP1,PTOV1 |
| 1.623e-09 | -20.24 | MORF_BECN1 | MSigDB lists | MORF_BECN1 | 93 | 38 | 17377 | 2626 |
RPLP2,UBN1,PRKCSH,SUMO2,MYH9,KLC1,BECN1,PARN,SRRT,TUBGCP2,TERF2IP,ATP6V0B,DNAJC8,ARHGEF1,CAPZA1,RPN2,RBM3,NAP1L4,MORC3,ERCC1,SEC61B,ATG9A,KRAS,CAPZA2,MTX1,PRKRA,RAB1A,POLR2A,PPP2CA,SMAD2,PPP2R5A,JAK1,B4GALT3,YWHAH,DDB1,NUDT3,ANXA11,CSNK1D |
| 1.657e-09 | -20.22 | BRUINS_UVC_RESPONSE_LATE | MSigDB lists | BRUINS_UVC_RESPONSE_LATE | 1056 | 230 | 17377 | 2626 |
NAT9,TSC2,AGRN,GNPDA1,TMEM41B,PIGQ,DNAJC24,CSNK2A1,EBNA1BP2,GYG1,NANS,CCNL2,IKBIP,MAP1LC3B,RUFY1,GIT2,CREM,PAPOLA,PRNP,PA2G4,AP3S2,SLC44A1,PPCDC,MECR,RPF2,RP2,NFU1,PTPRK,METTL1,SGCE,KLF10,SEPT9,AATF,DPM1,RBX1,PSMG1,MCL1,ICMT,MCM2,GINS4,ASF1B,CLNS1A,CHAF1A,STOML2,PRIM1,KRIT1,ABHD5,AHNAK,PDRG1,MAP4,QRSL1,MLYCD,CAB39,STK11,ACTB,CHEK2,SMG9,DVL1,OSGEPL1,CLN3,SASS6,CHPT1,PSMC1,CAPN1,DNAJC5,PPP1R12A,MUM1,VAV2,B4GALT1,HAUS4,DNAJB1,SLC35B1,RTKN,FKBP1A,RNF121,SLC31A1,LRRC8D,MCM5,ATIC,PPIL2,FBXO7,ZNF326,DAPK1,TPST1,MSH2,ATP6V0A2,KIFAP3,RBM3,PIKFYVE,SLC12A2,ATP6V0D1,HDHD2,CSNK1G3,PREB,FTL,PHF10,NUDT4,NQO2,MEMO1,PSMA1,KCTD20,C1orf35,ADRB2,FXR1,RHOB,NMT2,HAUS8,SCARB2,MTHFD2,FNTA,ZNF777,GALNT2,CCDC86,POLR2J,DCK,FAM83D,PIAS2,SIL1,SAMD8,PPP6R3,EHD4,TOB1,TSEN15,ALS2,SNX27,CYTIP,ATXN3,SARNP,TOMM20,RWDD1,CAST,SUMO2,PTTG1,UCK2,TCF19,APP,RPAIN,PAIP1,MEAF6,RAD23A,SHC1,UCHL5,DUT,SEPT11,TARDBP,RNASEH2A,AHCYL1,TALDO1,PDIA6,SAP30L,HTRA2,ARHGAP17,RFC3,SEC61B,KIAA0040,DRAP1,PSMB7,HTATIP2,PFKFB3,BOLA1,TOLLIP,GLOD4,CHCHD3,DSN1,VPS26B,STAT6,CAMKMT,ARNTL,H2AFX,RNF38,RBMS1,PDXK,B4GALT3,SMURF1,TSPAN5,PDF,ADAM23,COMMD10,CMAS,UNK,GCLM,MIF4GD,ANXA6,KLF13,WDR5,HMG20A,MAD2L2,MAN1A1,PDCD10,PTEN,TANK,ARHGEF1,PTPN11,BTF3L4,GEMIN6,TTC17,OSTC,CITED2,MTX2,RPL22L1,IMPA2,MYO5A,RPAP3,HEMK1,CSRP1,FAM49B,TCTEX1D2,TMEM126B,METTL5,CCDC34,COG1,ADSL,POLR3GL,RPA1,TMEM127,KPNA4,ATP6V1D,C1orf131,LTBP4,TWSG1,GPS2,SNAP29,PITX1,STX18,E2F1,RBPJ,ATP6V1C1,HRAS,GCSH,FAM83G |
| 1.675e-09 | -20.21 | RNA export from nucleus | biological process | GO:0006405 | 132 | 48 | 17256 | 2622 |
RPS15,NDC1,NUP188,CDC40,SARNP,THOC1,SRSF6,RAE1,RBM8A,ALKBH5,NUP54,AGFG1,NUP205,HNRNPA2B1,NUP210,EIF4A3,SRSF4,NUP107,UPF2,NUP153,GLE1,CHTOP,CPSF4,ZC3H3,NUP85,SEH1L,SRSF11,EIF5A,FYTTD1,NXT1,POLR2D,RNPS1,SLBP,NUP155,SRSF5,DDX39A,SYMPK,RPSA,SRSF1,TSC1,HHEX,UPF1,NUP62,SRSF3,RRS1,NUP58,NMD3,AAAS |
| 1.702e-09 | -20.19 | DDB1 (damage specific DNA binding protein 1) | protein interactions | 1642 | 257 | 80 | 17029 | 2761 |
NPHP4,CYLD,DCAF15,WDTC1,PMS2,CUL1,BECN1,GNB2,MOAP1,SAP130,TET3,MDM2,PCNA,SHC1,PIN1,DDA1,CDKN1B,CRY2,FTSJ3,CGGBP1,CDC5L,SAP30,COPS8,RBX1,CUL3,TOR1AIP2,AURKB,BRCA1,DCLRE1C,DCUN1D5,MBD3,BRWD1,STAT1,COPS6,DCAF5,HDAC2,WSB2,RECQL,CMAS,MCM10,EWSR1,CDT1,UBXN1,STRN4,BRAP,MEF2A,RGS2,TUBGCP2,RPA2,DTL,CLIC4,VASP,CCP110,PTEN,HUWE1,KMT5A,MCM5,BANF1,XPA,ZNF746,COPS7B,TERF2,DCAF6,KAT2A,SNX2,STRIP1,DCAF8,PSMA1,PCGF1,POLR2A,CAND1,RPA1,DERL1,POLR2J,DCAF11,E2F1,ACAT1,RBBP4,TERF1,DDB1 |
| 1.760e-09 | -20.16 | catalytic activity, acting on RNA | molecular function | GO:0140098 | 374 | 102 | 17224 | 2647 |
KARS,DDX47,NOP2,MRPL39,YTHDC2,ALKBH5,DHX8,LACTB2,POLR3K,EDC3,FARSA,DUS4L,IARS,EIF4A3,CD3EAP,METTL14,RNASEK,POP7,EXOSC1,RPAP1,RNASEH2A,ZNRD1,ZC3H3,FTSJ3,PDCL3,MRM2,RPP25,METTL1,LARS,SNRNP200,EXOSC6,POLR2G,POLR2L,HARS,NSUN2,METTL2A,POLR2D,DDX20,POLG2,DHX15,DHX57,RAD54B,PRIM1,DDX17,DUS3L,DGCR8,DHX16,WDR4,FTSJ1,IARS2,QRSL1,CRCP,RNASEL,DDX42,POLR2K,AGO2,DHX9,PARN,METTL3,PRPF18,TUT4,DDX56,EXOSC7,GATC,PPP1R8,CMTR2,RTCB,DUS2,DDX31,POLR1B,FBL,CNOT6L,CPSF4,MRM3,NSUN4,CARS2,DDX28,POLR2I,PRIM2,DDX24,DHX29,HELB,TYW1,POLR3GL,EXOSC9,DDX39A,TARS,TWISTNB,POLR2A,DDX23,EPRS,UPF1,POLR2J,QARS,TYW5,TRMT10B,CNOT6,DDX5,DTD1,TSEN15,TYW1B,DDX52 |
| 1.809e-09 | -20.13 | RPS6 (ribosomal protein S6) | protein interactions | 6194 | 210 | 69 | 17029 | 2761 |
NOP9,CYLD,NOP2,RPLP2,PRKCSH,CUL1,EBNA1BP2,SND1,RPL11,RPL23A,MDM2,EIF4A3,CRY2,TARDBP,EIF5,RPL29,RPL35,VHL,RPL38,CUL3,BRCA1,SLC25A5,RPS9,RPSA,RPS27A,RPS14,RPLP1,H2AFX,RRS1,FAU,ARRB2,SMURF1,RPS26,POT1,PTOV1,NIFK,RPS15,RPS2,DHX9,RPL15,LMNA,PNO1,RPL17,PTEN,ZNF746,UPF2,RPL19,FBL,PABPC1,HNRNPM,TERF2,STAU1,RPL8,ILF3,TUFM,RPL6,RPS10,RPS24,USP10,EIF2A,RPL27A,KIF11,CAND1,RPL36,NAP1L1,UPF1,RPL32,CD81,ZC3HAV1 |
| 1.855e-09 | -20.11 | HDAC1 (histone deacetylase 1) | protein interactions | 3065 | 550 | 143 | 17029 | 2761 |
ZNF76,ADD1,KDM4A,KMT2E,TSC22D3,CSNK2A1,TAF6L,CCNL2,CCNB1,UBE2I,MAP1LC3B,MAPK14,PARK7,PAPOLA,CREM,MBD4,RAP1A,PCNA,ZNF639,SMARCE1,DNMT1,SENP1,ZNF800,ARID4A,RYBP,SP3,BAZ2A,GABPA,VHL,EHMT1,MIER2,BRCA1,ZMYM3,UBTF,BRMS1,PWWP2B,TIMM13,SMAD2,CHD3,E2F4,SMAD1,SINHCAF,HDAC2,PTOV1,PWWP2A,PHB2,C16orf87,MEF2A,TOP2B,HAUS2,TFAP4,RB1,EXOSC7,HDAC7,MBD2,BANF1,PHF14,RTCB,AFF1,TNRC18,IFRD1,FOXK1,MTA2,ZMYND11,ELK1,CCT8,APPL1,IRF5,PHF6,PFDN5,KPNA1,TMEM54,CABIN1,RUVBL2,YY1,PPP6R3,RBBP4,CDKN2A,SMARCD1,DNMT3A,TRERF1,SUZ12,SUMO2,SMARCA4,RCOR3,PRKACA,CHD1,MXD1,SAP130,MDM2,MTA1,PIN1,SAP30L,STRAP,SAP30,CCT2,E2F3,PCGF6,NFATC2,MEF2D,MBD3,TRIM28,FKBP3,DDX17,HSPA4,TAB2,RBL1,HNRNPR,MAFK,STAT1,UHRF2,BEND3,H3F3A,SMAD4,NCOR2,MECP2,NUP54,TRAK1,WDR5,HMG20A,PRDM4,H2AFY,CREB1,STAT3,SMC4,PHF20L1,ZFP64,MIER1,RCOR1,MEN1,KPNA4,CCDC6,GPS2,BBX,TFDP1,E2F1,PML,DDX5,ACADM,RBPJ,NR2F2,TAF6,DDB1 |
| 1.897e-09 | -20.08 | astrocytoma_Grade_IV | COSMIC cancer mutations | astrocytoma_Grade_IV | 16366 | 2497 | 17385 | 2587 |
HECA,ZBTB10,ABCC10,HEXB,CCNL2,FBXO22,EEF2K,THAP4,RAD23B,ATP13A3,DNM2,ZNRD1,FTSJ3,USP34,CCDC57,ERCC1,NRAS,EHMT1,KIF15,HNRNPF,WDHD1,MIER2,DIDO1,MCM2,RAB22A,SMAD2,MID1IP1,RPS27A,MYO18A,OGT,MPV17,COX5A,SMAD1,ZNF75A,ANXA11,SLC25A33,SEC61G,GGA1,MUM1,CCZ1,TRIO,CUTA,RAB23,KCTD17,HAUS4,EIF2AK4,APH1B,PARN,CDC73,MYL6B,ATG4A,TMEM179B,PDXP,SMC3,GEMIN4,MVP,NUP85,PPP6R1,PABPC1,NSUN4,PPA1,IFRD1,AGGF1,FOXK1,RBM42,GTPBP4,MAP7D1,MRPL16,ELK1,EIF4H,RDH11,MAGED2,KPNA1,ETS2,TYW5,WIPI2,RUFY3,PDLIM5,ACSF2,RHOG,EXOC3,STARD7,VTI1A,C5orf30,INO80E,SLC35B2,LCLAT1,RCOR3,CPNE3,KIAA1147,RBM23,ZNF420,AHCTF1,TBC1D22A,TBC1D14,GMEB1,NSFL1C,SEPT11,GPD1L,ZC3H3,ARL5A,PDCL3,SNX8,ERMP1,EID1,IDH3A,POLR2D,HTATIP2,MEF2D,TMEM147,GSTCD,TANC1,MAT2A,VPS26B,NSMCE2,CORO1C,CAMKMT,PPP5C,PITRM1,TUBB,COMMD10,ZNF445,SRSF6,HABP4,CCM2,FLOT1,BTN3A1,ATG2B,ABHD14B,PPP1R3B,ZBTB45,HUWE1,ZNF260,NAA50,ANXA5,LTN1,UBE3B,NAP1L4,ZNF710,ST8SIA2,RPL22L1,MED22,SPTAN1,STAU1,DDX24,TCTEX1D2,TACC1,MRS2,LDHA,HEBP2,LLPH,RAB3IP,TTC33,PICALM,SH3BP5,SLC19A1,ACOX1,FAM3C,AEN,PARP10,YWHAH,THAP5,GPATCH4,FAM129A,TRIM11,YTHDC2,SNX15,RBM8A,ENSA,NENF,SND1,RUFY1,TRIM65,ZER1,PRNP,KRR1,RAB8A,NUP210,NT5DC1,NOC2L,EIF5,TACC3,RYBP,VPS13B,PTPN18,MIOS,SNRPB,MBLAC2,CDC6,UTP3,PBRM1,ODC1,USP21,TRAM2,FBXO28,BCL7C,ARRDC1,ADAM9,DVL1,NUMB,ZNF564,FUBP1,C1orf74,CTU2,PARP12,ZCCHC9,CENPF,LAMTOR3,CHCHD2,NCKAP1,LYRM2,RSAD1,TNS3,SUB1,RINL,SSBP3,MBD2,XPA,AHCY,RBM3,LRSAM1,HDHD2,NTPCR,NSDHL,AMD1,CAMSAP1,ZNF761,METTL22,ICAM2,STYXL1,APPL1,BBS12,RXRB,SDHB,PCM1,GALNT2,TMEM168,NLRC5,RUVBL2,BTBD10,MYO9A,CCNB2,USP7,GLT8D1,RPLP2,SUCLG1,ARID2,TMX4,SLC2A1,ATP6V1B2,PCBP1,LYN,BCAP31,VAV1,MRPL50,TMEM69,PSMA6,ZNF473,ZNF302,BRPF3,TARDBP,BCAP29,CTDSP2,PRPF19,PPIF,KDM3B,MND1,CLCN3,BIRC3,RAB7A,ANKRD33B,PPIE,CHMP2B,VDAC1,EIF3H,TMEM201,GLOD4,IDE,DHX16,UHRF2,CHMP4B,XRCC3,PARD3,BCL2L12,C19orf53,MCM10,KLHL21,PDAP1,CDCA8,TMX3,ARF1,SLC12A9,TUBGCP2,DNAJB9,HOMER1,POLR1B,RNF5,RBM15B,PPAN,RHOA,RPRD1A,BTAF1,TOP3A,ARHGEF12,PCGF1,DDX23,RAB18,CACNB1,TRIM26,PDCD6,ATP6V1D,L3MBTL3,FAM110A,NEIL3,CTBS,BBX,IMPDH1,TAF12,NR2F2,PGAM1,HIPK3,IFI16,TXN,NUP188,H2AFZ,PNISR,PRKCSH,USP39,UBE2I,PARK7,SLC25A37,ASPHD2,ZNF428,RAB4A,TRA2B,SUCLG2,TAF5L,SMARCE1,ZNF800,CDC5L,ZNF524,SGCE,OSBP2,NSUN2,USP22,CLNS1A,EIF3A,ZMYM3,DOT1L,IWS1,ANKRD10,WAS,KIF18B,TPP2,C1orf109,ZMAT3,B4GALT2,PRPF38B,RECQL,C9orf78,EWSR1,GADD45G,RRM1,ACAP1,B4GALT1,CYCS,FAM136A,SUPT7L,TMEM165,CNOT3,NPLOC4,SPAG5,WDR48,RTKN,CEP104,EXOSC7,KLHL5,LRRC8D,PPP4R1,MSH2,PIGG,OSTF1,FBXL7,MRPL40,TNRC18,SYTL3,FAM171A1,APOL1,EIF5A,GCC2,PRIM2,ELL2,RDH10,MFNG,RPS24,GORASP2,CAPZA2,ADRB2,CCT8,MTR,PHF6,PFDN5,SLCO4A1,TTC13,GOLGA2,RBMX,MED15,PIAS2,APPL2,SAMD8,CDKN2A,NUDT3,ZNF511,ATXN3,RAF1,KIAA0232,C2orf49,EPM2A,CD320,CCNA2,MTMR4,BRI3,TP53BP2,AQR,RBM12B,ILKAP,CDK12,SAP30,BRD4,DRAP1,NARF,LRRC8A,ELP4,ABHD11,PKMYT1,ASB13,SERP1,TRIM28,SUPT16H,EIF3K,CHMP4A,ATF6,XRCC4,ADAM23,PRPF4B,NDUFS1,DEPDC1,MECP2,SECISBP2,HMG20A,WWP2,SLC25A36,JAKMIP1,DNAJC8,AXIN2,CITED2,JMJD4,ANKRD37,KAT2A,TMEM126B,RABIF,ADSL,PACS1,BMS1,KCNQ1,ARSK,MACF1,KIF11,KLF6,COMMD4,SMAP2,FADD,SH3GLB1,MYO1F,CBX3,TMEM127,INF2,PPP1R11,DUSP11,DDX5,WDR62,TAF6,ESPL1,PURA,DDB1,DEF6,FAM83G,IPO4,UBL3,PIGM,NAT9,LYRM4,GPR132,UBE2Q1,PTP4A3,BRIX1,MRPL19,ZNF696,SF3B2,PCYOX1L,CDC42,SYNM,GOT2,JAZF1,HADHB,RPF2,SLC35C2,CNNM3,CARM1,SRPK2,WDR41,LARS,ZCCHC10,CCDC138,LRBA,SUMF2,KMT2C,OGFR,PRPSAP1,ASF1B,RPL37,MAN2A2,EIF4ENIF1,NIP7,U2SURP,MIA2,ZNF268,ATP6V0E1,PPP1R2,PM20D2,XPNPEP3,RGS2,LYAR,FAM89B,POLR2I,TRAFD1,SUGP2,GBA,SYVN1,DAPK3,ARHGAP15,MASTL,UAP1,NFIL3,FN3KRP,YWHAZ,CTSA,TMEM14A,TOB1,TSEN15,ADNP2,TCF12,PRKAB1,MDH2,SMARCA4,ORC1,RRN3,UBXN2A,IARS,CD3EAP,KIF14,EXOSC1,CS,CLTB,DNAL4,CSTF1,POU2AF1,UBQLN4,NXT1,HPDL,PGGT1B,SELPLG,SMU1,ATXN1,GLO1,OGDH,BICD2,CADM1,EDEM2,HERPUD2,TOLLIP,FANCE,MBD3,PDHX,RPS9,ALKBH6,SURF4,DUS3L,ARNTL,ANP32E,FKBP5,TMEM101,CCDC125,ABCA1,PDCD2L,GCLM,RAE1,DCTN2,NUP54,CHIC2,PAWR,MXD4,DCUN1D4,PIP4K2A,XPR1,KIF5B,KLHL20,SEC24C,RRBP1,ARHGEF2,ANP32A,LDLRAD3,STAT3,MYO5A,NIPAL3,AMPD2,TXNL1,PHF20L1,DCAF6,FAM49B,TMEM39A,ATP2C1,RFFL,COG1,RCOR1,PRMT2,TFEB,LEMD2,UPF1,ELMO1,ZC3H7B,DTX4,ZMIZ1,TERF1,HRAS,CCDC93,FGFR1OP,TMED7,PIGQ,AGPAT1,CNTROB,PPP1R16B,MIS12,GSDMB,TTC9C,PDS5B,NUP153,SENP1,PGAP2,TMEM115,PLEKHM3,DCUN1D5,PLEKHF2,BRMS1,PWWP2B,TRIM47,WDR11,AXIN1,SMG9,TRIM52,LONP2,NDUFV2,PHF23,CERK,SLC4A2,EZH1,ITGB5,LMNA,MCTS1,DDX56,EIF2S2,SLC38A5,FOXN2,CARS2,PRRC2A,C16orf72,RB1CC1,ZMYND11,PGS1,MYBL2,UHRF1BP1,SRSF5,MPG,MATR3,CYB5A,NCDN,POLR2J,SETD3,TEX30,PTAR1,CNOT6,NDE1,EGLN1,ZNF207,ANKRD27,PPP1R37,ABCA3,IVNS1ABP,MON1B,RMI2,TMEM97,NIT2,NUF2,ZNF267,TCF19,TMEM161B,KTN1,APP,PRKD3,CLUAP1,ATP2A2,UTP18,GRSF1,DUT,ZCCHC2,ANAPC7,RNF19A,FAM76B,CLN6,TMEM9,GCC1,RNF169,ADCY7,ATP6V1G1,ENPP4,RNPS1,CDCA2,FKBP3,GPR137,DDX17,CHCHD3,PEX5,CDC16,HIPK2,MBOAT1,TICAM1,PDXK,ZBTB11,ANXA6,TMBIM4,GMCL1,UBE4A,IL21R,ETS1,WRB,ZNF92,PNO1,CAPN2,ADD3,SUV39H2,TTLL12,TPCN1,TMX1,LYPLA2,HNRNPM,MFSD12,LDHB,PPP3CA,NUDT8,POLK,JTB,EMP3,MTMR12,ZP3,PDE3B,KIF18A,CCDC6,WNT5B,MAPK6,C4orf46,LY75,SLC25A19,RGL1,PSAP,WDR76,IGBP1,FAF1,SNAPIN,COX15,THOC1,AGRN,GNPDA1,GPBP1L1,PPP1R15B,CSNK2A1,EBNA1BP2,GIT2,BIRC2,ATPAF1,DLG5,ABL2,XRCC2,ZFYVE27,MCMBP,PTPRK,CDC37,METTL1,SP3,EXOSC6,HARS,GMFB,ESYT1,ANLN,RAB5B,RHEB,DPYSL3,TBC1D17,TIMM13,CDCA4,TONSL,NRM,NAGLU,ACTB,ZNF45,TMUB1,CTCF,ASAH1,DOCK11,CRLF3,ASXL2,LRRC14,NUS1,SLC27A4,AFF1,MDFIC,MAML1,CYTH1,NQO2,UTP15,EIF2AK1,EIF4G2,ZDHHC3,MOSPD3,ITPRIPL1,CDC27,SNAP23,TBPL1,PRMT7,KCTD7,NDUFA5,CYLD,UGP2,DYNLL1,COPE,HCFC1R1,ZADH2,GGPS1,RPAIN,RAD23A,ATP6V0B,PDK2,STRBP,DUS4L,MRPL34,PDCD2,SAP30L,SLC39A9,CLPTM1,RPL29,RPL35,BTG2,DNAJC9,MTMR6,FRAT2,NFATC2,KDM1B,ARL5B,USP36,CCDC127,MRPL2,ATP1A1,CLK3,PSMD3,MAFK,NDUFA11,CEP55,ZNF436,DNAJC17,NCOA1,SLC25A39,ZC3HC1,ZNF146,ATXN7L2,CDC40,SMAP1,GOLIM4,RRP15,DAP,GNE,SMC6,ARFIP2,NKRF,CHAC2,BZW2,WRNIP1,SS18L1,CENPM,PTGES3,CAMK2G,MLEC,ZNF202,PPWD1,FAM50B,RHOT2,NEU1,TPD52L2,GOLGA7,TWSG1,GLG1,PGRMC1,FAM126A,RPS6KC1,UBE2C,PPCS,NDUFB6,TMEM41B,ZDHHC8,PLXNA1,CCNB1,SLC20A1,COMMD6,ABHD14A,POLR3K,C14orf119,ASAP2,SNUPN,CNPY4,TFG,PLCL2,SEH1L,ATG9A,PBK,MKI67,DDX20,AMDHD2,GALNT7,SLC17A5,CCNF,FOXRED1,RBM47,PTER,WDR4,DHTKD1,TRAF5,HDAC2,PWWP2A,HSPH1,MAPRE1,CHTF18,ADO,KIF23,SLC35B1,NOTCH2,JMY,NDUFAF6,FKBP1A,SLC31A1,SNX18,ATIC,ATP6V0A2,PIKFYVE,RNF135,LPCAT1,EEF1D,TMED2,PHF10,FTL,DDX28,ZNF84,SIGMAR1,PIP4K2C,RIT1,PLEC,KDM3A,SF3A2,FAS,EPRS,ZNF777,TMEM54,QARS,PPP3R1,TCOF1,NRBP1,CABLES1,DNMT3A,RWDD1,CKLF,TRIP10,SF3B1,RPS6KA1,SUZ12,CAST,RAC1,GPR89A,OLA1,SNN,GNB2,FLAD1,APLP2,KDM2A,TNPO2,CDKN1B,TALDO1,GPX4,ATP13A1,RFC3,MAPRE2,ERF,CUL3,SLBP,KIAA1586,H2AFV,POLG2,GAR1,PSMB9,DHX57,NSA2,HSPA4,MRPL55,JAK1,TBL3,SEL1L,H2AFX,KLHDC4,B4GALT3,PDCD11,ATMIN,POLQ,POU3F2,OTUD5,NCOR2,ANKRD13D,PKP4,SCAMP3,BABAM1,CDCA3,SLC25A12,BLM,TMCC3,GTF2F1,RPL17,CRAT,AHSA1,PRC1,UPF2,COPS7B,SLC38A10,CNOT6L,CNPY3,UBE2M,IFT46,TMEM160,TSHZ1,ZFP64,DENND4C,DENND1B,WDR18,RPL8,ILF3,LRRC1,RHOT1,TSR2,MARK2,ECH1,PRDX1,PLD3,NUCB1,GNA12,FBXO21,C1orf131,PRDX3,PFDN4,HNRNPH3,STX18,TFDP1,KHSRP,ASNA1,CPEB2,SSSCA1,BYSL,VPS29,S100PBP,MIB2,IER2,PTMS,NOP2,UBN1,DCAF15,NF1,ALKBH5,MOGS,UBE2Z,TAF6L,MAPK14,BECN1,SNAPC4,RNF103,BCAT2,MBD4,C18orf32,METTL14,IMPAD1,ZNHIT6,RCSD1,PHTF1,SRI,KIF22,ZBTB22,NFU1,OGG1,TRIM14,ELOF1,COPS8,FYTTD1,TRIM8,RRM2,SOX4,ABHD5,UBTF,CXXC4,PAF1,UEVLD,SPATA2,PQBP1,IARS2,ATXN2L,GALNT10,STARD3NL,RPS15,PIGN,AGTRAP,CIB1,XPO7,SRRT,ZNF449,CAPZA1,GLTP,BCL2,KIFAP3,N4BP2,HP1BP3,VOPP1,THNSL1,ISG15,CAND1,GNAS,TSC1,RBM25,CDCA5,ZFP90,NANP,RBBP4,ZBTB24,SMARCD1,MBD1,WASF2,MMACHC,TOMM20,IFI27L1,GNPNAT1,MPHOSPH8,HNRNPUL2,CHD1,MEAF6,C2orf68,CCDC50,AKAP8,PARL,RPN2,CHTOP,FAM3A,F2R,TMEM14C,SCYL3,ABI1,HTRA2,MOSPD1,RLIM,FAM172A,ZNF500,PSMB7,NLN,WIPF1,BOLA1,BUD13,NDUFB1,PEF1,EIF3G,BTBD1,TAB2,CHCHD1,TULP3,WDR59,CANT1,SCARB1,GAS2,USP11,SMURF1,PPP2R2D,TSPAN5,CDS2,MAGEH1,MRPL42,EYA1,CDK2AP2,MRPS26,LETMD1,KLF13,HDDC2,RGS1,MAN1A1,FBXO5,GART,TANK,BRD7,MRPL11,SAMD4B,ZDHHC18,GTF3C6,POLR3GL,WDR81,MEN1,ZNF407,MFN2,COX8A,ZRANB2,SRSF3,MBD6,ATP6V1C1,IDH3B,TATDN1,TSC2,LACTB2,CMTM6,RBM4,ZNF275,RPL23A,CDKN2C,NAPG,USF1,MECR,AP1M1,UPRT,CRY2,ECD,RNF26,TIPARP,LRRC59,ANKRD9,RHBDD2,MGAT5,BAK1,ZNF559,RHOBTB3,GABPA,WBP1,NUTF2,ARF4,GINS4,KRIT1,BOLA3,AHNAK,RAD18,PDRG1,RNASEL,CHPF2,OAZ1,PDCD4,SMNDC1,NXT2,HIVEP3,KIAA0100,CLSPN,RHOC,DHX9,PDCD7,PSMD9,HAUS2,COPB2,TFAP4,CD59,RNFT1,RIMS3,MEGF8,EFTUD2,FBXO7,CPSF4,MRPL21,PHKG2,LUC7L2,SRSF11,EIF3L,MTA2,TYW1,USP10,ITM2A,SSR2,BCLAF1,MTX1,SFXN5,FNTA,PDLIM1,TMEM159,MRPL3,ALS2,FAM72A,TRIM41,KARS,NQO1,POC1A,ANK3,PTTG1,TPX2,TBC1D13,DAZAP2,STMN1,GLRX3,C19orf48,REPS1,ABHD16A,FBXL6,SH3BP1,MTA1,UBA5,CLCN6,INTS12,C8orf59,RPRD1B,CGGBP1,CPNE1,SEC61B,POLR2L,FAM118B,GOPC,E2F3,CIRBP,RPL38,CRNKL1,PFKFB3,GORAB,RAB1A,GIGYF1,TMEM184C,PPP2CA,KIF2A,CCDC14,LSM6,RNF38,SNRPG,DMWD,USP13,ZFP91,TRMT6,IP6K2,WDR5,SLC25A43,PMVK,IFT27,NEIL2,RRP36,SRXN1,RPA2,PSMD2,CLIC4,PDCD10,CBWD2,COQ4,ITGB8,ARF5,ARHGEF1,FBXL19,TTPAL,UTP20,MAGT1,GPS2,DBI,SSNA1,MRFAP1L1,CD81,TMEM131,WDR13,FANCI,PAPOLA,CREM,FANCL,TET3,GLIS2,IL6ST,INTS1,POP7,SLC44A1,MTPN,ASB6,PLK1,RPP25,CELSR2,SEPT9,RBX1,APH1A,RAD51AP1,CKAP2L,PSMG1,UBE2V1,EAF2,IL12RB1,KRTCAP2,LUC7L,LSG1,NECAP2,C1orf122,TRIM4,ALG3,AGPAT2,CHD3,ZNF367,E2F4,PRPF4,KPNA2,BEND6,CLN3,DNAJC30,NGLY1,POT1,MYL12B,CCDC137,RMND5A,HJURP,DNAJB2,FAM53C,NKD2,SDC2,KLC1,CDK13,ADCK5,COX4I1,DNAJB1,RAB6A,ARID1B,C1GALT1,MLX,UBE2Q2,CCP110,ZNF746,ARL6IP1,CTR9,NIPSNAP1,ABHD2,DCAF8,ACSL3,LDB1,MAP4K3,ARMC8,RBM38,NMT2,IRF5,RPL36,HAUS8,MBIP,ORMDL2,COX7A2L,ZDHHC7,SIL1,FAM122A,DTD1,UNC13C,BCCIP,SART1,TRAF7,NDUFAF2,TOR1AIP1,ZNF416,LAGE3,TM9SF3,ZFYVE21,RRAGC,ZNF121,OIP5,NRF1,WDR44,PPME1,PIN1,EFCAB11,RPAP1,CABLES2,LMAN1,AHCYL1,TOP1MT,STRAP,SPSB3,ZNF583,SNX25,ARHGAP17,POLR2G,ZNF780B,PPT1,NUP155,DCLRE1C,MRPS14,RHBDF2,SUGP1,RBL1,FASTK,UBXN2B,STK38,AP1S1,SPRYD4,SLC22A23,H3F3A,CHID1,SMAD4,RAD51D,SLC30A9,CMAS,UNK,NADSYN1,HMGN3,NCAPG,SCYL2,FZD6,HERC3,GTPBP3,CTSS,ORC3,RNLS,YTHDC1,ACP2,HMGN5,CSRP1,METTL5,ABCF2,TUFM,RANGAP1,PNPLA8,HAGH,API5,ZFR,SEC23IP,E2F1,USP20,TMEM219,RBPJ,MAX,PDCD6IP,LUZP1,ADAM10,CXXC1,TSC22D3,AP3M2,CUL1,GYG1,NANS,OAT,MYEF2,ANKRD26,PA2G4,NOL11,FIZ1,ZNF200,MARCH2,SLC26A2,SRP72,KLF10,LACTB,RFC2,CBFB,RAB2B,PRIM1,MAP3K4,HHEX,RPS14,LUC7L3,MAP4,MRPL27,BTF3,PTPDC1,CCDC59,NMD3,PTOV1,COX5B,DNAJC5,SCOC,DHPS,POLR2K,ANKH,PRKAA1,VAV2,C16orf87,GSPT2,DLGAP4,PXMP2,PRPF39,PSEN1,ZNF79,PDXDC1,VPS25,NDUFS7,YY1AP1,C12orf10,FAM192A,RPN1,LHX8,ARPC5,ZNRF2,DAPK1,TPST1,PIK3IP1,CYC1,SOCS5,FDFT1,PIGT,WDR1,EMB,ZNF574,C1orf35,EXOSC9,ARID1A,PTTG1IP,C9orf40,FXR1,GOSR1,MAP2K2,TWISTNB,AKAP1,XRCC5,HMGN2,PI4K2A,CAT,SEC31A,DERL1,HSPBP1,MTHFD2,CEBPG,ARAP1,USP32,FAM83D,CABIN1,SMPD4,GPI,CYTIP,TP53RK,REPS2,RAB11B,UROD,SLC39A13,POMP,BCL2L1,DECR1,RALB,SIAH1,LPIN2,ADCY9,SOCS6,MRPS27,TTC3,RNASEH2A,CFL1,ANKLE2,CDC123,OAF,VDAC2,EDF1,ERC1,EML4,AMZ2,ANKZF1,ZNF282,RAD51C,DSN1,DDOST,HINT1,DGCR8,SAFB,HAGHL,LMBR1,FTSJ1,RWDD4,NCLN,BEND3,EYA2,DYNC1LI2,SLC41A1,B4GALT5,MANBA,TKT,FAM76A,CBLL1,ARGLU1,LANCL1,POFUT1,FAM8A1,HEATR5B,HLA-A,EBP,RFWD3,NDUFA2,FUT8,BTF3L4,PTPN11,MRPL54,FEM1B,RPL19,CNN2,NDUFA3,MTX2,MSH6,PDLIM2,LONRF3,RFXANK,FBXO9,GUF1,RPL32,ZHX1,NDUFS5,WDR91,HIGD2A,ZBED3,RORB,POLA2,ZNF76,MTX3,COPA,HMGXB3,PHRF1,ABCB10,COMMD5,MAP1LC3B,DST,SIVA1,RAB35,GPATCH1,TCEA1,DRAM2,DEAF1,SNRNP200,NCK1,LAP3,VHL,SREK1,ARHGDIB,PITPNB,HSPB11,BRWD1,PPM1G,SH3GLB2,CRCP,BAZ1B,ACBD4,CAB39,STK11,CLU,CHEK2,ZSWIM3,TSTD2,CHPT1,MRPL13,DCAF5,CAPN1,UBE2D3,NSMCE4A,PPP1R12A,ZCCHC8,GORASP1,UBXN1,NACA,PCSK7,RPL15,THRAP3,TTF1,QSOX2,PRPF18,NUP205,CHKA,MED10,ZRANB1,MCPH1,SLC12A2,ATP6V0D1,CSNK1G3,CREG1,NUDT4,RPL6,VKORC1,SLTM,EVC2,KLHL15,SIAH2,SLC16A1,EHD4,SNRNP70,C11orf1,APOL2,N4BP2L2,SNX27,CHMP2A,CORO7,FEZ2,PMS2,UCK2,UCK1,CLCC1,EXT2,MXD1,USP5,HNRNPA2B1,SAP130,NVL,PPP6C,CYB5R1,ZNF770,EBAG9,RNF25,PCGF6,METTL2A,FAM72B,PON2,HNRNPR,STAT6,HPS5,MAPK1,BRD9,TMEM33,NAT14,DNAJC2,TRIP12,SHPRH,SCYL1,VPS45,MYO9B,GFM2,SPPL2A,FASTKD3,FGFR3,MZT2A,PPIG,ZDHHC13,TMEM99,H2AFY,ATG13,NDUFS8,ERI3,FBL,SLC35A1,FRMD8,MICAL3,TGFB1,B3GALT6,ELOVL5,HEMK1,TIMMDC1,HELB,PSPC1,MIER1,SCFD2,NDRG3,ARL17A,MTMR3,ACAT1,CENPT,PLOD3,RAB3IL1,ZSWIM6,RAB14,ADD1,MRPS15,KDM4A,XIAP,DHX8,GLUD1,ANKRD23,PABPC4,CALM2,CDK5,PSMD1,NEK6,NSRP1,RABGAP1L,SRSF4,FNIP2,KCNAB2,PCBP2,MLST8,PLK3,ZNF672,HSDL1,MRPL43,TOPORS,MCL1,SMC2,PPFIA3,ICMT,SLC50A1,STOML2,LIMK1,ZNF689,PRDX5,ATE1,MLYCD,ATP6V0C,ST3GAL2,FBXL3,TFDP2,E2F2,PFKP,AAAS,DDX42,SSRP1,MRPL9,MRPS2,STRN4,TOP2B,ZNRF3,TMED3,DDRGK1,RAVER2,GNS,INTS7,INPP5A,MCM5,PHF14,ZNF326,NAGPA,TIMM8B,ETV3,TSPAN31,DHX29,TEX10,MAN1B1,RPS10,CBFA2T2,ABCF1,RHOB,LRRC14B,DTWD1,PTPRF,SCARB2,OSBPL11,CCDC86,DUSP3,SLAIN1,MDH1,HEXA,RNF139,SNX14,ZNF296,TRERF1,UBR2,CHD1L,ACTR3,WDTC1,MYH9,CREBL2,NIPA2,PRKACA,SAFB2,ANKIB1,STAM,ARL6IP6,RAB21,SP100,ZKSCAN1,DDA1,NUP107,ANKRD13C,MAVS,CEP63,TMEM136,RBM15,ATF2,DCTN1,SHOC2,PSRC1,MAP4K4,WBP2,ATP6V0A1,DNAJA1,NDUFA7,TAZ,C19orf54,TAF2,SEC61A1,WDR7,RPLP1,CBLN2,RBMS1,FUS,GEN1,LRP8,COIL,LRCH1,GALK1,ZNF786,RPS2,SESTD1,TRAK1,JMJD6,SIKE1,AKT1S1,KRI1,FBXO3,ERH,NDUFB4,PPP1R8,PRDM4,GTSE1,GEMIN6,DCP1A,SGCB,S100A6,IMPA2,NUDC,PDPK1,TK1,GUK1,TNFAIP3,GALC,ZNF512,KIAA0930,MRPS10,DDX39A,RPA1,ZNF862,ZNF180,KEAP1,POLE,TATDN2,PITX1,CAPN7,LRPPRC,PML,HMGB2,USF2,ANAPC4,SRM,DDX47,MCCC1,CDC42SE2,S1PR2,CDIPT,SEC16A,SSR1,LIN9,PCNA,ZNF639,TRMU,PIK3R2,ETV6,TXLNA,PPCDC,FAM86C1,MYBL1,MRPL32,CCAR1,ABCC5,PBXIP1,BAZ2A,TLK1,MRPL12,EZR,LNX2,LRP5,BRCA1,PRKRA,STX16,EPB41,OPTN,SEPT1,SOCS4,QRSL1,OSGEPL1,GLCCI1,NUDT11,GEMIN7,SEPHS2,LZTR1,RACGAP1,PPP3CB,B4GALT4,RLF,RAPGEF6,SNRNP25,RB1,VASP,MED8,VMP1,PPIL2,MEA1,TIMELESS,AHDC1,ALDH18A1,TMEM8A,ABCC1,PREB,TRAPPC9,AACS,MEMO1,KRAS,RTF1,UBE4B,NFATC2IP,LY6E,ARPC1A,ZNF174,PSMC4,GOLGA4,PALB2,SYNCRIP,PRPS2,NIPA1,TIGD2,RNF114,FOXM1,MRPL39,XAB2,SUMO2,DUSP22,COMMD8,RPL11,CSDE1,MDM2,CORO1A,MINPP1,METTL9,POC5,DVL2,GM2A,PSMA8,COQ10B,CPOX,TIGD5,SLC26A6,CYP20A1,PRPF3,TXNL4A,RPSA,SRSF1,DNAJC10,SCAP,ZNF700,PLEKHG4B,TIMM17A,FAU,LTA4H,AP2S1,USP53,INTS2,CTDP1,MIF4GD,CDT1,ARID5A,SUMF1,GGA2,AP3S1,CSNK1A1,RMI1,TFRC,PTPN2,STARD9,IRF4,GSTK1,NDUFV1,SLC1A4,CWC27,SLC35B4,DDX31,ABCD1,RPAP3,CNTN5,SNX2,ZMYM5,CCDC34,CHCHD6,BSDC1,KPNA4,CDKN2AIPNL,FBXO41,BIRC5,TFE3,SNAP29,CDCA7L,PKD2,ACADM,CHMP7,SAT2,GCSH,ZNF496,TMEM109,TAP1,NHLRC3,IKBIP,EIF1B,ELMOD2,KIFC1,DBNDD1,CYB5RL,RNASEK,CDC25B,PRADC1,DNMT1,NOL12,ORAI2,USO1,AKT2,NOL8,GNG7,AURKB,MCFD2,SLC25A5,ZFAND5,MAK16,STT3A,TMED10,PSMD8,EIF2D,ITGB1,PTPN7,UQCRH,RRS1,ARRB2,RTN3,SVIP,DDX58,WSB2,PPIB,MUT,GMFG,HLA-E,NDUFA4,MAN2B1,METTL3,CFLAR,NDUFS4,RNF121,MEX3C,KLF16,HDAC7,DAD1,BDH1,PCYT2,GNAI2,ANKHD1,MORC3,TERF2,KCTD20,SEPT8,DCTD,PKM,TOMM40,ADSS,SERTAD2,SERF2,ZFP92,NSF,DCK,ERGIC3,ACLY,LPCAT4,VCPIP1,YY1,PPP6R2,PPP6R3,MAP3K5,RNF14,CDK2,ZC3HAV1,SYS1,ZBTB37,URB2,EIF3D,MAGED1,KLHL18,ADPGK,SLC25A44,AP1B1,SDHA,PAIP2,PHC2,CRKL,MOAP1,TERF2IP,CYHR1,ZNF75D,SHC1,UCHL5,NAA35,TMBIM1,CCT2,CDKN2AIP,MKLN1,HMGN4,GALK2,CDC23,SHCBP1,AP4E1,PRDM11,VEZF1,PPP2R5A,ACYP1,STAT1,PPA2,TRIM32,RHEBL1,C1orf112,MRI1,TCF3,BRAP,AGPAT3,MYNN,SDF2L1,SPR,RAB11A,REEP5,FOXO3,MAD2L2,CCDC28A,PIP5K1C,RBM17,MAT2B,PTEN,CENPJ,TAGLN2,OSTC,CREB1,PACS2,NCOA2,SMC4,RNASEH2C,NEK7,NET1,PARP4,TBRG4,ANAPC2,RPL27A,YIF1A,SGSH,HGS,TTLL4,SLC38A7,MFAP1,CCDC69,BRWD3,ESYT2,SKA3,NPHP4,UBE2E2,HNRNPAB,PLXNC1,ST13,TMEM184B,DNAJC24,ZNF107,SLC29A1,KIF2C,AGFG1,SIRT2,FKBP2,USP48,UBQLN2,SNRPD3,CUTC,EDC3,UBLCP1,ZNF804A,RAP1A,THADA,EIF4A3,AP3S2,ATG3,DPYSL2,PPP1R12C,AKR1B1,NDUFB9,JOSD1,RP2,TTC4,TECR,ARID4A,FGFR1OP2,TIMM50,TDP1,DPM1,FOPNL,SLC16A7,WDR82,SLC25A22,STK17B,DHX15,CHAF1A,GEMIN5,COPS6,SASS6,RPS26,PSMC1,SLC12A7,TBC1D12,TM9SF4,ZNF768,UFC1,MED13L,TIA1,MEF2A,EPHX2,PITHD1,RHBDD1,NFATC3,BANF1,BUD31,ZNF335,YBX1,KNTC1,ACAD8,UBE3C,ZNF189,ALDH9A1,KDELR1,TSTA3,CIC,OXR1,PSMA1,SEPT7,TMEM241,NAP1L1,ODF2,EXOC4,KIAA1328,NUP62,PITPNA,NAA20,PTDSS1,MZT2B,PDSS2,C7orf26,TMEM106C,IMMT,ASH1L,CHERP,WDYHV1,PLAGL2,CHKB,IRF3,TWF2,PAIP1,ANKRD28,ANKLE1,FARSA,SAR1A,SCAMP4,APOOL,PDIA6,ACSL5,TOR1AIP2,AZI2,GFER,RAD54B,DAP3,TMEM41A,ZNF317,GADD45B,AKNA,REEP4,CBX4,MIF,KIF3B,GOLPH3L,SH2D3A,CASP6,TOR3A,SRGN,DBF4,MFSD10,SAC3D1,CTNNBL1,YIF1B,CLDND1,TTC17,SLC25A1,GINS1,PAQR6,CSNK1G2,TELO2,ADAM17,HMGN1,NASP,ASPM,PPP1R21,PRKAR1B,SYMPK,TARS,SNRPA,MAPK3,HSPA1B,HLA-B,ATAD2,PLAA,ZNF330,OSBPL8,KBTBD7,PREPL |
| 1.919e-09 | -20.07 | ILF3 (interleukin enhancer binding factor 3) | protein interactions | 3609 | 338 | 98 | 17029 | 2761 |
RAB14,SART1,CYLD,MPHOSPH8,IVNS1ABP,XAB2,MRPL39,SUZ12,SF3B1,CUL1,BIRC2,RPL11,SSR1,RPL23A,RAP1A,MDM2,EIF4A3,MRPS27,RPAP1,TRA2B,NDUFB9,RPN2,TARDBP,LRRC59,MRPL32,CDC5L,RPL29,VHL,MRPL12,RNPS1,CUL3,BRCA1,MCM2,MRPS14,MRPL55,HNRNPR,DGCR8,DHX16,RPS14,IARS2,UQCRH,NCLN,FUS,ARRB2,RPS26,RPS2,MRPL9,MRPL42,PHB2,RAE1,DHX9,RPL15,RAB11A,QSOX2,LMNA,RPA2,RPN1,NDUFV1,MEX3C,NDUFA2,HUWE1,RPL17,MCM5,RRBP1,ZNF746,ZNF326,RBM3,RPL19,MRPL40,ALDH18A1,MRPL11,LPCAT1,PABPC1,STAU1,PRKDC,SF3B6,RPL6,RPL8,MRPS10,RPS24,SRSF5,EIF2A,SF3A2,MATR3,PICALM,POLR2A,RPA1,CAND1,SYNCRIP,RPL32,LRPPRC,PGRMC1,SRSF3,YY1,SNRNP70,ZNF830,CDK2,NUP58 |
| 1.921e-09 | -20.07 | Rab5c (RAB5C, member RAS oncogene family) | protein interactions | 19345 | 110 | 44 | 17029 | 2761 |
CHMP2A,COX5B,NDUFV2,IMMT,GOLIM4,TMUB1,NDUFS1,PHB2,TMEM109,TAP1,DNAAF5,FLOT1,ATP6V1B2,TMEM165,KTN1,TFRC,XPR1,NDUFV1,NDUFA2,NDUFB4,ABCD1,ATP6V0D1,RNF5,ERMP1,ERLIN1,METTL5,RPS10,VDAC2,ATP6V0A1,COG1,NDUFA7,CHMP2B,VDAC1,NDUFB1,RAB5B,GOSR1,STOML2,CCDC127,CHCHD3,GALNT2,MRPL55,MRPL27,PIEZO1,NDUFS5 |
| 1.962e-09 | -20.05 | HNRNPC (heterogeneous nuclear ribonucleoprotein C (C1/C2)) | protein interactions | 3183 | 177 | 61 | 17029 | 2761 |
CCDC93,SART1,CYLD,MRPL42,IVNS1ABP,GSPT2,XIAP,DHX9,CUL1,CSNK2A1,SMARCA4,USP39,UBE2I,CSNK1A1,LMNA,SF3B2,EIF4A3,MCM5,PIN1,BANF1,EFTUD2,AP1M1,TARDBP,MRPL40,HNRNPM,CDC5L,SRPK2,STAU1,SNRNP200,VHL,PRKDC,WDR18,RPL6,SMU1,RNPS1,CUL3,ILF3,SREK1,KRAS,BRCA1,SEPT7,MCM2,MATR3,SF3A2,PHF6,XRCC5,FAS,CAND1,KPNA4,PALB2,HNRNPR,CLK3,RBMX,H2AFX,KPNA2,RRS1,CDK2,ARRB2,NKAPD1,CDKN2A,SMARCD1 |
| 1.979e-09 | -20.04 | GO_SPINDLE_POLE | MSigDB lists | GO_SPINDLE_POLE | 113 | 43 | 17377 | 2626 |
CTDP1,PKP4,KLHL21,POC1A,CENPF,TPX2,CCNB1,MAPK14,RAB11A,TUBGCP2,SPAG5,CALM2,CEP104,SMC3,NEK6,PRC1,KNTC1,CDC25B,CEP63,DCTN1,PLK1,PSRC1,ASPM,NEK7,CUL3,TUBGCP5,CKAP2L,CDC6,RANGAP1,TOPORS,AURKB,KIF11,HAUS8,KIF2A,PPP2CA,GOLGA2,FAM110A,ODF2,FAM83D,NUP62,VPS4A,WDR62,NDE1 |
| 1.982e-09 | -20.04 | covalent chromatin modification | biological process | GO:0016569 | 369 | 100 | 17256 | 2622 |
USP7,MBD1,ASH1L,DNMT3A,KDM4A,KMT2E,UBR2,SUZ12,CXXC1,NSD3,TAF6L,SIRT2,CCNB1,CHD1,MEAF6,TET3,CCNA2,KMT5C,BRPF3,KDM2A,MTA1,TAF5L,ATF2,SAP30L,ARID4A,CARM1,RYBP,SAP30,KDM3B,BAZ2A,KAT7,EHMT1,RIOX2,PCGF6,ELP4,MIER2,WDR82,USP22,AURKB,KDM1B,KMT2C,MBD3,USP21,USP36,DOT1L,PAF1,BRMS1,CHD3,OGT,BAZ1B,BEND3,NCOA1,PPP5C,NAA60,EYA2,HDAC2,EYA1,MECP2,PRKAA1,JMJD6,EZH1,WDR5,SUPT7L,RLF,CDC73,IRF4,SUV39H2,HUWE1,KMT5A,MBD2,HDAC7,PRDM4,ZNF335,NAA50,CTR9,KANSL2,FBL,ZFP64,KAT2A,MTA2,MIER1,LDB1,RCOR1,RTF1,MEN1,PRMT2,PCGF1,KDM3A,MBIP,EPOP,SETD3,TEX30,KMT2B,PRMT7,RUVBL2,TAF12,RBBP4,CDK2,SGF29,DDB1 |
| 1.989e-09 | -20.04 | GO_DNA_REPLICATION | MSigDB lists | GO_DNA_REPLICATION | 193 | 62 | 17377 | 2626 |
POLA2,DNAJC2,PTMS,MCM10,CLSPN,THOC1,CHTF18,CDT1,DBF4,RMI2,RRM1,TOP2B,ORC1,INO80E,BLM,RMI1,RPAIN,WRNIP1,DTL,RPA2,PCNA,MCM5,DUT,TIMELESS,RNASEH2A,ORC3,TOP1MT,MCMBP,GINS1,RFC3,NASP,PRIM2,POLK,HELB,KAT7,NOL8,TOP3A,SLBP,RRM2,CDC6,BRCA1,MCM2,RFC2,POLG2,GINS4,CHAF1A,RPA1,PRIM1,SUPT16H,NAP1L1,UPF1,POLE,TONSL,RBMS1,DTD1,RBBP4,ZNF830,CDK2,PURA,SLC25A33,SSRP1,POLQ |
| 2.037e-09 | -20.01 | SRSF3 (serine and arginine rich splicing factor 3) | protein interactions | 6428 | 137 | 51 | 17029 | 2761 |
DDX47,CYLD,EWSR1,COPA,NOP2,SUZ12,SRSF6,COPE,TAP1,DHX9,TIA1,CUL1,USP39,SND1,PCBP1,CHD1,APP,LMNA,HNRNPA2B1,EIF4A3,HUWE1,ZNF746,BUD31,TRA2B,PCBP2,HNRNPM,SRPK2,SRSF11,EXOSC6,SMU1,CUL3,ILF3,ATP6V0A1,SREK1,SRSF5,MCM2,EIF4H,MATR3,SF3A2,DHX15,SRSF1,DDX17,CAND1,SYNCRIP,TIMM17A,FAM3C,PGRMC1,SNRNP70,CD81,HNRNPDL,FUBP1 |
| 2.053e-09 | -20.00 | RRS1 (ribosome biogenesis regulator homolog) | protein interactions | 23212 | 169 | 59 | 17029 | 2761 |
RPS15,NIFK,RPS2,NOP2,RRP15,RPLP2,SF3B1,DHX9,EBNA1BP2,BRIX1,RBM4,RPL11,RPL23A,KRR1,DDX56,EIF4A3,RPL17,RBM34,NOC2L,RPF2,YBX1,RPL19,GLE1,FBL,ZC3H3,FTSJ3,CDK12,MRPL32,HNRNPM,STAU1,RPL29,RPL35,ZNF512,RPS10,RPL6,GTPBP4,CUL3,RPL8,SREK1,RPS24,KRAS,BMS1,DIDO1,SRSF5,RPS9,MATR3,RPSA,DHX57,NSA2,DAP3,RPL32,RPS14,RPLP1,RBMS1,NMD3,PURA,ZC3HAV1,IFI16,GPATCH4 |
| 2.066e-09 | -20.00 | MORF_FEN1 | MSigDB lists | MORF_FEN1 | 61 | 29 | 17377 | 2626 |
CCT2,POLR2I,H2AFZ,HNRNPAB,CHERP,FOXM1,NSDHL,RRM1,DNAJC9,CYCS,CCNB1,VDAC1,RFC2,TRIM28,NUP205,HDDC2,SRSF1,PCNA,HSPA4,DHX16,MFAP1,AHSA1,PPM1G,PTPN11,BAZ1B,TARDBP,KPNA2,ESPL1,NUDC |
| 2.084e-09 | -19.99 | SND1 (staphylococcal nuclease and tudor domain containing 1) | protein interactions | 27044 | 114 | 45 | 17029 | 2761 |
ZNF207,LZTR1,RPS2,CYLD,PRKAA1,DHX9,CSNK2A1,NENF,NANS,UBE2I,APP,CPNE3,RPL23A,RPN1,PA2G4,MDM2,DNAJC8,HUWE1,UBA5,CS,ANXA5,RPL19,TARDBP,HNRNPM,PDPK1,RPL35,MRPL12,VDAC2,MYBL2,CUL3,BRCA1,USP22,MCM2,RPS9,POLR2A,CAND1,HNRNPR,STAT6,GPI,SRSF3,RBPJ,CDK2,RPS26,MYL12B,SMNDC1 |
| 2.112e-09 | -19.98 | MORF_CDC16 | MSigDB lists | MORF_CDC16 | 68 | 31 | 17377 | 2626 |
SRP72,RMND5A,DEAF1,IMMT,MAPRE1,PRKDC,VDAC2,SLBP,DCTD,XPO7,DDX39A,CBFB,NDUFS4,RAD23A,XRCC5,KRIT1,SDHB,CDC16,IARS,HNRNPR,DUT,SAFB,LRPPRC,KHSRP,TNPO3,BAZ1B,ANP32A,TARDBP,RBPJ,PDIA6,PTDSS1 |
| 2.136e-09 | -19.96 | LDHA (lactate dehydrogenase A) | protein interactions | 3939 | 153 | 55 | 17029 | 2761 |
MIF,BCCIP,UNK,COX15,PRKCSH,RPS6KA1,DYNLL1,TKT,NIT2,ARF1,SPR,SDHA,PARK7,CDC73,RPA2,PCNA,HUWE1,PPME1,ARF5,AHSA1,ZNF746,SUCLG2,UPF2,TCEA1,TALDO1,ATF2,CFL1,LDHB,STAU1,KAT2A,PPT1,WDR1,LDHA,CUL3,BRCA1,PKM,VDAC1,MCM2,RAB1A,KIF11,ISG15,ARF4,RPA1,CAND1,CAT,SDHB,IDE,PRDX5,MDH1,ACADM,FUS,CDK2,TERF1,POT1,ANXA11 |
| 2.183e-09 | -19.94 | GSE6674_ANTI_IGM_VS_ANTI_IGM_AND_CPG_STIM_BCELL_DN | MSigDB lists | GSE6674_ANTI_IGM_VS_ANTI_IGM_AND_CPG_STIM_BCELL_DN | 189 | 61 | 17377 | 2626 |
SRM,NOP2,GADD45G,SLC2A1,ARID5A,UCK2,AGPAT3,EBNA1BP2,BCL2L1,SND1,PRNP,FKBP1A,PPP1R3B,HOMER1,EXOSC7,NOL11,EIF4A3,UTP18,ATIC,BDH1,EXOSC1,NOC2L,FNIP2,NAP1L4,GEMIN4,FBL,PDIA6,PPAN,TGFB1,LARS,HEMK1,SEPT9,KAT2A,FAM118B,IDH3A,UTP15,TBRG4,MRPS10,PSMG1,ADSL,DCTD,BMS1,EIF3G,MAK16,SNRPA,TARS,MAT2A,CYB5A,CAND1,HSPA4,MTHFD2,GOLGA7,CCDC86,NIP7,CDCA7L,PRPS2,ACLY,AEN,LRP8,BYSL,GCSH |
| 2.191e-09 | -19.94 | Golgi membrane | cellular component | GO:0000139 | 729 | 167 | 18223 | 2701 |
TMED7,RAB14,COPA,ADAM10,CDIPT,SEC16A,RIC1,RAB8A,ASAP2,CDC42,RAB35,AP1M1,DNM2,TFG,MGAT5,RHBDD2,PGAP2,USO1,TMEM115,RHOBTB3,NRAS,APH1A,GALNT7,PITPNB,MCFD2,STX16,SLC50A1,RHEB,RAB2B,OPTN,MAN2A2,TMED10,MYO18A,ST3GAL2,ROCK1,GALNT10,CLN3,CHPT1,CHPF2,RTN3,NAA60,B4GALT2,SVIP,SCOC,AGTRAP,GORASP1,HLA-E,PCSK7,B4GALT1,NOTCH2,SLC35B1,TMED3,RAB6A,B4GALT4,PSEN1,TMEM165,COPG2,QSOX2,COPB2,CD59,RNF121,C1GALT1,TPST1,PIKFYVE,LPCAT1,PPP6R1,TMED2,KDELR1,PREB,NAGPA,CYTH1,TRAPPC9,MAN1B1,MFNG,USF3,GORASP2,GOSR1,ZDHHC3,SEC31A,SCARB2,GOLGA4,GALNT2,GOLGA2,NSF,ARAP1,ZDHHC7,SAMD8,SMPD4,PPP6R3,CORO7,GNPNAT1,SYS1,RAC1,GPR89A,SLC2A1,COPE,VTI1A,SLC39A13,RXYLT1,SLC35B2,AP1B1,BCAP31,EXT2,APP,ANKRD28,RAB21,SAR1A,PPP6C,LMAN1,GCC1,MOSPD1,EBAG9,CHP1,CLCN3,GOPC,CUL3,PKMYT1,RAB1A,PEF1,AP4E1,ERC1,SURF4,SCAP,GOLGA8A,CANT1,AP1S1,ATF6,B4GALT3,CSNK1D,GOLIM4,GOLPH3L,TMBIM4,B4GALT5,VPS45,ARFIP2,AGPAT3,ARF1,HLA-A,MAN1A1,PDCD10,SEC24C,FUT8,ZDHHC13,SLC35B4,YIF1B,ST8SIA2,SLC35A1,B3GALT6,MOB4,ATP2C1,COG1,RFFL,PNPLA8,SPPL2B,SH3GLB1,YIF1A,HLA-B,NUCB1,PDCD6,SEC23IP,GOLGA7,SNAP29,STX18,GLG1,HRAS,GPR89B,SNAPIN |
| 2.209e-09 | -19.93 | microtubule organizing center | cellular component | GO:0005815 | 702 | 162 | 18223 | 2701 |
FGFR1OP,PDCD6IP,NPHP4,KMT2E,WDR13,TAP1,CNTROB,KIF2C,SIRT2,CCNB1,KIFC1,CALM2,ANKRD26,DLG5,RAB8A,PCNA,NEK6,CDC42,XRCC2,DNM2,RP2,CDC25B,SPATC1L,TACC3,PLK1,PLK3,RPP25,FOPNL,KIF15,EZR,CKAP2L,TOPORS,AURKB,BRCA1,CCNF,SEPT1,HSPB11,RAD18,CHD3,ROCK1,VPS4A,SLF1,TRAF5,SASS6,C2CD5,AAAS,TMUB1,MAPRE1,PPP1R12A,CENPF,DHX9,RAB23,CIB1,KIF23,HAUS4,PSEN1,HAUS2,RAPGEF6,SPAG5,DTL,CEP104,CCP110,KIFAP3,FBXL7,MCPH1,GNAI2,ATP6V0D1,PSMA1,CCT8,HAUS8,MASTL,PCM1,CDC27,ODF2,NLRC5,SLC16A1,NUP62,RUVBL2,NDE1,CFAP20,CDK2,ECPAS,CCNB2,MZT2B,ALS2,BCCIP,NDC1,CYLD,FAM92A,POC1A,DYNLL1,TPX2,OLA1,NIT2,BCL2L1,PRKACA,RAD23A,CLUAP1,ABRAXAS2,CEP63,RNF19A,RPRD1B,POC5,DCTN1,TUBGCP5,BICD2,CENPU,KIF2A,CDC16,PPP2R5A,CCDC14,CEP55,H2AFX,AKNA,MAPK1,GEN1,SMAD4,RAD51D,DYNC1LI2,CSNK1D,KIF3B,CTDP1,MZT1,MECP2,DCTN2,SCYL1,FLOT1,WDR5,SPDL1,CSNK1A1,IFT27,RAB11A,TUBGCP2,SAC3D1,KIF5B,STARD9,MZT2A,CLIC4,SLC1A4,CENPJ,AXIN2,IFT46,KAT2A,TCTEX1D2,TACC1,NEK7,ASPM,JTB,SPPL2B,HSPA1B,KIF18A,NEK1,ATP6V1D,KEAP1,FAM110A,SNAP29,E2F1,USP20,SSNA1,PKD2,WDR62,ESPL1 |
| 2.211e-09 | -19.93 | organonitrogen compound biosynthetic process | biological process | GO:1901566 | 1441 | 299 | 17256 | 2622 |
PPCS,GXYLT1,MRPS15,ZDHHC8,PIGQ,GLUD1,OAT,EIF1B,RBM4,PABPC4,EEF2K,RPL23A,UPRT,SLC26A2,SPTSSA,MGAT5,MRPL57,PGAP2,TMEM115,MRPL43,GALNT7,MCFD2,EIF3A,STOML2,STT3A,RPS27A,RPS14,MRPL27,EIF2D,OGT,DHTKD1,ST3GAL2,CHPF2,ZNF598,OAZ1,PFKP,B4GALT2,COX5B,MRPL9,MRPS2,DHPS,GSPT2,B4GALT1,TMEM165,PSEN1,MCTS1,ATG4A,RPN1,EIF2S2,DAD1,ATIC,EFTUD2,CTPS1,PIGG,ATP6V0A2,MRPL40,CYC1,MRPL21,LPCAT1,PABPC1,PPA1,EEF1D,CARS2,NAGPA,EIF5A,EIF3L,PIGT,DHX29,NOA1,MAN1B1,MFNG,RPS10,RPS24,DCTD,MRPL16,PKM,EIF4H,MTR,ABCF1,ADSS,EPRS,GOLGA2,DCK,QARS,TYW5,SAMD8,SMPD4,GPI,WIPI2,HEXA,MRPL3,KARS,RWDD1,EIF3D,UROD,STARD7,RXYLT1,SLC35B2,ADPGK,EFL1,FLAD1,PRKD3,DUT,LPIN2,ADCY9,MRPS27,PDCL3,ADCY7,RPL38,ATP6V0A1,NDUFA7,POLG2,SERP1,EIF3K,ALDH3B1,MRPL55,DDOST,CERS6,GUCY1B1,PPA2,FTSJ1,RPLP1,PDXK,B4GALT3,GALK1,RPS2,B4GALT5,MRI1,TRAK1,SECISBP2,SDF2L1,ATP5F1B,SPR,POFUT1,ERH,GATC,RPL17,FUT8,MRPL54,LTN1,RPL19,ST8SIA2,OSTC,GTF2H2,RPL22L1,TK1,GUK1,LDHA,RPL8,MRPS10,ADSL,RPL27A,GUF1,RPL32,MAGT1,ATP5MC3,DBI,OAZ2,NAXE,PARP10,WDR45B,CPEB2,SRM,ADA2,PIGM,COX15,AGRN,MOGS,CSNK2A1,ATP5PF,MRPL19,BCAT2,TET3,GOT2,SLC44A1,PPCDC,EIF5,SLC35C2,MRPL32,ABCC5,LARS,DPM1,HARS,MRPL12,KRTCAP2,ODC1,ALG3,GEMIN5,MAN2A2,RPL37,IARS2,QRSL1,DHFR2,GALNT10,MRPL13,CHPT1,RPS26,SEPHS2,RPS15,PIGN,GORASP1,SDC2,RPL15,B4GALT4,RSAD1,CHKA,C1GALT1,NUS1,PYURF,AHCY,MRPL48,ALDH18A1,ALDH9A1,ATP5IF1,AMD1,RPL6,GBA,SYVN1,EIF2A,LY6E,EIF4G2,ZDHHC3,NMT2,RPL36,MBIP,GALNT2,PRPS2,TBPL1,ZDHHC7,ATP5F1A,NIPSNAP2,PTDSS1,MMACHC,CYLD,RPLP2,MRPL39,UCK2,UCK1,CHKB,EXT2,PAIP1,RPL11,MRPL50,FARSA,IARS,MRPL34,RPN2,LMAN1,TMEM14C,RPL29,RPL35,CPOX,OGDH,MRPS14,RPS9,EIF3G,RPSA,EIF3H,MRPL2,DAP3,CHCHD1,CANT1,ABCA1,SLC25A39,PDF,GCLM,NADSYN1,MRPL42,AGO2,MRPS26,PAWR,CHAC2,GFM2,HDDC2,MAN1A1,GSTK1,GART,RRBP1,PELO,MRPL11,RNLS,B3GALT6,TGFB1,AMPD2,ELOVL5,ZDHHC18,CSNK1G2,CNTN5,TUFM,NADK2,ATP5MF,HAGH,TARS,GOLGA7,ACAT1,IMPDH1,ACADM,PLOD3,PGAM1 |
| 2.236e-09 | -19.92 | Ksr1 (kinase suppressor of ras 1) | protein interactions | 16706 | 228 | 73 | 17029 | 2761 |
ST13,HNRNPAB,NOP2,RAF1,MAGED1,CSNK2A1,SEC16A,RPL23A,PA2G4,HADHB,TECR,LRRC59,CDC37,PRPF19,CCT2,EXOSC6,RFC3,SLC25A22,DNAJA1,SLC25A5,EIF3G,TRIM28,RPS9,EIF3H,EIF3A,PPP2CA,PAF1,DNAJC10,HSPA4,RPS14,PSMD3,PPM1G,KPNA2,MAPK1,TUBB,HSPH1,PPIB,EWSR1,TMX3,DNAJB1,PSMD2,SMC3,EIF2S2,RPL17,PELO,YBX1,RPL19,GEMIN4,NAP1L4,LUC7L2,MSH6,RPAP3,EIF3L,RPL8,RPS10,C1orf35,RPL27A,CCT8,MAP2K2,PSMB3,PSMC4,MAGED2,NAP1L1,RPL32,RBMX,YWHAZ,DDX5,RUVBL2,PPP6R3,YWHAH,HNRNPDL,IPO4,DDB1 |
| 2.243e-09 | -19.92 | GSE12366_PLASMA_CELL_VS_MEMORY_BCELL_DN | MSigDB lists | GSE12366_PLASMA_CELL_VS_MEMORY_BCELL_DN | 176 | 58 | 17377 | 2626 |
RAB14,RECQL,TRERF1,RPS6KA1,RAE1,EIF3D,MYH9,RRAGC,PAWR,TGOLN2,ZNF267,DCUN1D4,GGPS1,ARID1B,VASP,RPL17,DUT,GMEB1,PABPC1,CFL1,RNF169,MORC3,PGAP2,LARS,MAPRE2,ZNF559,ETV3,BIRC3,KAT2A,C16orf72,ZNF512,ERLIN1,DENND4C,UTP3,GALNT7,DCLRE1C,RPL27A,DHX15,SRSF1,HMGN2,PRIM1,NSA2,PFDN5,NAP1L1,SERTAD2,OSBPL11,RPL32,JAK1,HNRNPR,RPS27A,DCK,TATDN2,STAT6,SNAP23,PTAR1,GALNT10,OSGEPL1,CHMP7 |
| 2.260e-09 | -19.91 | nuclear chromosome segregation | biological process | GO:0098813 | 265 | 78 | 17256 | 2622 |
ZNF207,CHMP2A,NDC1,PDCD6IP,DYNLL1,PTTG1,ACTR3,NUF2,KIF2C,CCNB1,BECN1,MIS12,KIFC1,ANKLE1,AHCTF1,ABRAXAS2,KIF14,AKAP8,NUP107,PDS5B,KIF22,MCMBP,SEH1L,PLK1,PSRC1,TAOK1,CUL3,NUSAP1,SMC2,AURKB,CHMP2B,CDC23,CENPU,KIF2A,RAD51C,CHMP4A,DSN1,KIF18B,CEP55,CHMP4B,VPS4A,RRS1,DYNC1LI2,MAPRE1,PHB2,PHF23,CDT1,CENPF,CDCA8,KIF23,TOP2B,RACGAP1,PMF1,SPDL1,NCAPG,RAB11A,SPAG5,RB1,SMC3,PRC1,NAA50,KNTC1,CENPM,NUP85,SMC4,NUDC,RANGAP1,LEMD2,KIF18A,BIRC5,CDCA5,FAM83D,NUP62,CENPT,NDE1,CHMP7,TERF1,ESPL1 |
| 2.266e-09 | -19.91 | SANSOM_APC_MYC_TARGETS | MSigDB lists | SANSOM_APC_MYC_TARGETS | 198 | 63 | 17377 | 2626 |
MIF,POLA2,TP53RK,FOXM1,FLYWCH2,PPP1R15B,CXXC1,ABCC10,ADO,TRMT6,TKT,PMF1,BCL2L1,SLC35B2,ABHD14A,WRB,POFUT1,TFRC,PABPC4,WDR48,RAD23A,DTL,GTPBP3,USF1,HOMER1,SIVA1,INTS1,EXOSC1,FUT8,TXLNA,FEM1B,SCAMP4,SGCB,MED22,PRPF19,METTL1,PLK3,TELO2,PSRC1,KAT2A,SIGMAR1,NCK1,LDB1,ARHGEF12,MEN1,SOX4,KLF6,EPB41,POLE,SEC61A1,CORO1C,WDR4,CTBS,BCL7C,RNF38,USP20,ATF6,WIPI2,TATDN1,WDR62,DCAF5,ATMIN,FAM83G |
| 2.345e-09 | -19.87 | viral transcription | biological process | GO:0019083 | 113 | 43 | 17256 | 2622 |
RPS15,NDC1,NUP188,RPS2,RPLP2,RAE1,DHX9,NUP54,MON1B,RPL15,NUP205,RPL23A,RPL11,USF1,NUP210,RPL17,NUP107,RPL19,NUP153,NUP85,SEH1L,RPL29,RPL35,RPL6,RPL8,RPL38,RPS10,RPS24,NUP155,RPL27A,RPS9,RPSA,RPL36,RPL37,RPL32,RPS27A,RPS14,RPLP1,NUP62,USF2,RPS26,NUP58,AAAS |
| 2.350e-09 | -19.87 | protein modification by small protein removal | biological process | GO:0070646 | 298 | 85 | 17256 | 2622 |
USP7,TOMM20,CYLD,ATXN3,USP39,INO80E,USP48,BECN1,STAM,BIRC2,USP5,RAD23A,CCNA2,PSMA6,PSMD1,BABAM2,MDM2,ABRAXAS2,UCHL5,RAD23B,JOSD1,MAVS,SENP1,USP34,COPS8,BIRC3,PSMA8,PSMB7,USP22,BRCA1,KDM1B,PSMB9,USP21,USP36,SMAD2,RPS27A,PSMD8,PSMD3,AXIN1,OGT,ACTB,DMWD,USP11,COPS6,SMAD1,ARRB2,PSMC1,USP53,SMAD4,USP13,DDX58,OTUD5,CLSPN,BABAM1,ASXL2,PSMD9,WDR48,PSMD2,CCP110,PTEN,AXIN2,COPS7B,RNF135,ZRANB1,RHOA,KAT2A,FOXK1,TNFAIP3,USP42,PSMA1,USP10,ADRB2,OTUD3,RHOT1,PSMB3,PSMC4,KEAP1,HGS,EPOP,USP32,SIAH2,VCPIP1,USP20,MBD6,YY1 |
| 2.355e-09 | -19.87 | MARTORIATI_MDM4_TARGETS_FETAL_LIVER_DN | MSigDB lists | MARTORIATI_MDM4_TARGETS_FETAL_LIVER_DN | 487 | 123 | 17377 | 2626 |
MBD1,PNISR,ST13,FOXM1,IVNS1ABP,ADAM10,SUZ12,TMX4,XIAP,ENSA,YTHDF3,USP48,SAFB2,RCOR3,SSR1,PAPOLA,ANKRD28,SHC1,ZKSCAN1,MTMR4,IL6ST,SLC44A1,F2R,LRRC59,CTDSP2,CCAR1,PRPF19,FYTTD1,UBQLN4,TIMP2,NRAS,FAM172A,RAB7A,CUL3,KIF15,SREK1,PITPNB,USP22,UTP3,SOX4,ZFAND5,SLC25A5,RAB22A,SRSF1,DPYSL3,DDX17,SUPT16H,DGCR8,TBL3,RWDD4,RNF38,BAZ1B,ANP32E,CSNK1D,ZNF146,TMEM33,FUBP1,SLC12A7,RMND5A,PRPF38B,MAPRE1,DHX9,TIA1,SMC6,MEF2A,THRAP3,ETS1,SCYL2,TFRC,SPAG5,NUP205,GTF2F1,DTL,NFATC3,ADD3,PTEN,ATIC,PPIG,ZNF260,PPP4R1,PRC1,NAA50,TNPO3,FEM1B,CNOT6L,PPP6R1,CSNK1G3,HP1BP3,TSHZ1,STAU1,PHF20L1,SNX2,ELL2,NUDT4,ZMYND11,DHX29,ABCF2,UTP15,ZNF574,KCTD20,RTF1,RANGAP1,BCLAF1,MEN1,KIF11,MARK2,MATR3,ABCF1,SH3GLB1,CAND1,SH3BP5,GNA12,EPRS,RBM25,CDC27,MAGT1,TWSG1,GPS2,HNRNPH3,ODF2,PSAP,ZNF830,HIPK3 |
| 2.389e-09 | -19.85 | GO_MITOCHONDRIAL_MEMBRANE_PART | MSigDB lists | GO_MITOCHONDRIAL_MEMBRANE_PART | 138 | 49 | 17377 | 2626 |
NDUFA5,COX15,NDUFV2,IMMT,TOMM20,NDUFS1,NDUFB6,UQCR10,NDUFA4,ABCB10,COX4I1,LYN,SDHA,PARK7,NDUFS7,NDUFS4,NDUFV1,NDUFA2,NDUFB4,TIMM23,BDH1,NDUFB9,NDUFS8,APOOL,NDUFA3,TIMM50,PPIF,BAK1,NOA1,NDUFA7,TOMM40,RHOT1,NDUFB1,RHOT2,FOXRED1,CHCHD6,MFN2,AKAP1,CHCHD3,SDHB,ANKZF1,TIMM17A,TOMM6,NDUFA11,COX7A2L,COX8A,COX5A,UQCRH,NDUFS5 |
| 2.391e-09 | -19.85 | GSE15330_WT_VS_IKAROS_KO_HSC_DN | MSigDB lists | GSE15330_WT_VS_IKAROS_KO_HSC_DN | 185 | 60 | 17377 | 2626 |
MBD1,WASF2,SLC12A7,CCNC,CTDP1,GMFG,MUM1,ANKH,CERK,C19orf25,KLF13,UBE2Z,RACGAP1,SLC4A2,GLUD1,NCKAP1,TWF2,MFSD10,CAPN2,CDK5,GSTK1,ZBTB45,ETV6,RRBP1,SLC44A1,FAM89B,DNM2,CDKN1B,KIFAP3,CABLES2,STAT3,MYO5A,LUC7L2,KDELR1,PREB,SAP30,SNX2,OAF,MYBL2,MTMR6,LRRC8A,CDC6,AURKB,PITPNB,COMMD4,STK17B,SF3A2,SMAP2,FBXO21,ATP6V1D,TAB2,TMED10,HIPK2,CORO1C,IMPDH1,CTSA,EHD4,SNX14,SMAD4,CAPN1 |
| 2.391e-09 | -19.85 | GSE8835_HEALTHY_VS_CLL_CD8_TCELL_UP | MSigDB lists | GSE8835_HEALTHY_VS_CLL_CD8_TCELL_UP | 185 | 60 | 17377 | 2626 |
RAB14,PKP4,LYRM4,CHIC2,RACGAP1,NOTCH2,GYG1,ATP6V1B2,AP3S1,PCBP1,CUTC,WRB,KIAA1147,SRXN1,SEC11A,FASTKD3,TNS3,MTA1,ARHGEF1,PRC1,SLC35B4,EI24,AXIN2,SEPT11,CABLES2,ACAD8,CITED2,PCBP2,WDR41,NAGPA,SNX8,TGFB1,ADAM17,POLK,ZMYND11,UTP15,CKAP2L,LRRC8A,COG1,MAP7D1,SMC2,PEF1,MBD3,NDRG3,UBTF,ZHX1,CORO1C,STAT6,ATXN2L,H2AFX,C4orf46,CBLN2,CAB39,PDXK,IDH3B,EHD4,USF2,TSPAN5,RPS26,POT1 |
| 2.391e-09 | -19.85 | GSE41867_NAIVE_VS_DAY30_LCMV_ARMSTRONG_MEMORY_CD8_TCELL_DN | MSigDB lists | GSE41867_NAIVE_VS_DAY30_LCMV_ARMSTRONG_MEMORY_CD8_TCELL_DN | 185 | 60 | 17377 | 2626 |
CCNC,DDX47,NDUFS1,TXN,MCM10,MPHOSPH8,POLR2K,TRIP10,UQCR10,FAM129A,SCYL1,OLA1,C5orf30,SECISBP2,POMP,RUFY1,CDC73,NPLOC4,KRI1,THAP4,MCM5,EFTUD2,AKR1B1,TTC4,C8orf59,MCMBP,UBE2M,POC5,SLC25A1,NTPCR,GTF3C6,MKLN1,DENND4C,LYRM1,CAMSAP1,SUMF2,BOLA1,TMEM147,OGDH,NUTF2,CDC23,API5,EIF4H,MBD3,TWISTNB,CAND1,ALG3,BOLA3,KPNA4,HSPBP1,SEC23IP,FBXO28,PDLIM1,UBXN2B,TBL3,ST3GAL2,LTA4H,PSMC1,CCDC59,ANAPC4 |
| 2.466e-09 | -19.82 | PRDX2 (peroxiredoxin 2) | protein interactions | 7001 | 107 | 43 | 17029 | 2761 |
PDCD6IP,CYLD,EWSR1,TXN,CUL1,CYCS,NANS,SPR,PSEN1,PCBP1,APP,PARK7,CD320,UCHL5,DUT,RNASEH2A,TALDO1,PPA1,TMEM9,MSH6,GPX4,CDC37,METTL1,LAP3,PPT1,LDHA,PKM,MCM2,PRDX1,GLOD4,CAND1,CAT,SGSH,SEC23IP,HINT1,PRDX3,PRDX5,KHSRP,YWHAZ,CDK2,PGAM1,ANXA11,FUBP1 |
| 2.492e-09 | -19.81 | GO_ORGANELLE_LOCALIZATION | MSigDB lists | GO_ORGANELLE_LOCALIZATION | 397 | 105 | 17377 | 2626 |
CHMP2A,PDCD6IP,RAB11B,ACTR3,AP3M2,MYH9,KIF2C,CCNB1,SEC16A,BECN1,LYN,ANKRD28,KIFC1,CDK5,CDC42,AP3S2,DPYSL2,KIF14,PPP6C,DNM2,KIF22,LMAN1,TFG,SEH1L,DCTN1,USO1,PSRC1,CUL3,EZR,NUSAP1,BICD2,CDC23,MCFD2,RAB1A,CHMP2B,TMEM201,HHEX,CHMP4A,TMED10,MAP4,CEP55,OGT,STK11,CHMP4B,VPS4A,RRS1,CLN3,NMD3,DYNC1LI2,CSNK1D,KIF3B,RPS15,DNAJC5,GORASP1,EYA1,CENPF,DCTN2,CDCA8,KIF23,MEF2A,ARF1,RAB6A,AP3S1,PSEN1,RAB11A,SPAG5,PIP5K1C,KIF5B,CD59,PDCD10,SEC24C,ARHGEF2,KIFAP3,SYTL3,PPP6R1,MYO5A,TMED2,PREB,TRAPPC9,KAT2A,ASPM,WDR81,RHOT1,RHOT2,MARK2,MFN2,SEC31A,KIF18A,PCM1,SEC23IP,GOLGA2,NSF,BIRC5,SNAP29,SNAP23,CDCA5,LRPPRC,FAM83D,YWHAZ,PPP6R3,NDE1,CHMP7,TERF1,ESPL1,SNAPIN |
| 2.498e-09 | -19.81 | GSE6674_ANTI_IGM_VS_PL2_3_STIM_BCELL_DN | MSigDB lists | GSE6674_ANTI_IGM_VS_PL2_3_STIM_BCELL_DN | 194 | 62 | 17377 | 2626 |
SRM,DNAJC2,MAPRE1,GOLIM4,NOP2,IVNS1ABP,SUZ12,MRI1,RMI2,BLM,BRIX1,SEC16A,PCBP1,C19orf48,CHD1,MRPL19,RRN3,EIF2S2,AHCTF1,MLX,UTP18,HUWE1,SEC24C,BDH1,UBA5,ZDHHC13,NUP153,FNIP2,PIKFYVE,ALDH18A1,LYPLA2,KCNAB2,ABCC1,RPP25,EIF5A,B3GALT6,TGFB1,CLCN3,LARS,SEPT9,KAT2A,NSUN2,CUL3,E2F3,TMEM147,ODC1,TARS,MAT2A,ARF4,CAND1,NUCB1,EPRS,HSPA4,STT3A,TPP2,TFDP1,SIAH2,AEN,ZRANB2,TCOF1,LRP8,FUBP1 |
| 2.501e-09 | -19.81 | DNA integrity checkpoint | biological process | GO:0031570 | 150 | 52 | 17256 | 2622 |
CLSPN,CDT1,BABAM1,TOP2B,EIF2AK4,CCNB1,BLM,CNOT11,MAPK14,FANCI,CNOT3,RFWD3,DTL,RPA2,PCNA,MDM2,BABAM2,INTS7,CENPJ,PTPN11,MSH2,GTSE1,TIMELESS,CDKN1B,CEP63,CNOT6L,ATF2,CARM1,PRPF19,CDC5L,PLK1,PLK3,PRKDC,BTG2,TAOK1,MRNIP,CDC6,BRCA1,SOX4,DOT1L,CNOT9,RPS27A,E2F4,TFDP1,E2F1,PML,H2AFX,CNOT6,CHEK2,TFDP2,ZNF830,CDK2 |
| 2.520e-09 | -19.80 | PRR11 (proline rich 11) | protein interactions | 55771 | 96 | 40 | 17029 | 2761 |
RPS15,NOP2,SF3B1,RPL15,CTCF,EBNA1BP2,BRIX1,TTF1,PABPC4,RPL23A,SF3B2,KRR1,KRI1,LYAR,NVL,RBM34,RPF2,DDX31,ZNF800,FTSJ3,ZNF189,HP1BP3,NOL12,STAU1,DDX24,ZNF512,LLPH,NSA2,UPF1,CCDC86,NIP7,E2F4,ZNF689,E2F1,DUSP11,RRS1,ZBTB11,PURA,GPATCH4,ZBTB24 |
| 2.522e-09 | -19.80 | GNF2_RFC4 | MSigDB lists | GNF2_RFC4 | 58 | 28 | 17377 | 2626 |
GINS1,CCT2,RFC3,H2AFZ,MCM10,FOXM1,ASPM,RAD51AP1,CENPF,RRM1,SLBP,SMC2,MCM2,KIF11,FANCI,PRIM1,SUPT16H,PCNA,CCNA2,BIRC5,MSH2,TIMELESS,KNTC1,CCNB2,UBE2C,MSH6,SMC4,SSRP1 |
| 2.530e-09 | -19.79 | inner mitochondrial membrane protein complex | cellular component | GO:0098800 | 128 | 46 | 18223 | 2701 |
NDUFA5,NDUFV2,COX5B,IMMT,NDUFS1,NDUFB6,UQCR10,TIMM21,NDUFA4,COX4I1,ATP5F1B,ATP5PF,SDHA,PARK7,NDUFS7,NDUFS4,NDUFV1,NDUFA2,NDUFB4,TIMM23,MICU2,NDUFB9,NDUFS8,CYC1,APOOL,NDUFA3,TIMM50,PPIF,ATP5IF1,DMAC2,NDUFA7,ATP5MF,NDUFB1,FOXRED1,CHCHD6,SDHB,CHCHD3,ATP5MC3,TIMM29,TIMM17A,NDUFA11,COX8A,COX5A,UQCRH,NDUFS5,ATP5F1A |
| 2.584e-09 | -19.77 | PRDX1 (peroxiredoxin 1) | protein interactions | 5052 | 130 | 49 | 17029 | 2761 |
CYLD,TXN,SUZ12,TKT,CUL1,IRF3,NANS,CCNB1,SPR,CDC73,USP5,RAD23A,FERMT3,RPA2,SHC1,CDC42,EIF4A3,PTEN,UCHL5,MCM5,ARHGEF2,UBE2M,MSH6,CFL1,METTL1,LAP3,PPT1,VHL,PRKDC,CUL3,BRCA1,MPG,MCM2,LUC7L,PRDX1,ISG15,ZFR,RPA1,CAND1,TRIM4,CAT,PRDX3,PRDX5,DNPH1,FUS,COPS6,CDK2,TERF1,SMARCD1 |
| 2.608e-09 | -19.76 | GRAHAM_NORMAL_QUIESCENT_VS_NORMAL_DIVIDING_DN | MSigDB lists | GRAHAM_NORMAL_QUIESCENT_VS_NORMAL_DIVIDING_DN | 83 | 35 | 17377 | 2626 |
MCM10,RRM1,RACGAP1,KIF2C,NCAPG,SAC3D1,DTL,OIP5,SNRNP25,PCNA,CCNA2,MCM5,DUT,PRC1,MSH2,RNASEH2A,CENPM,MINPP1,NUP85,GINS1,PPIF,RFC3,TK1,RAD51AP1,KIF15,RRM2,CDC6,NUSAP1,SMC2,MCM2,KIF11,KIF18B,BIRC5,CEP55,CCNB2 |
| 2.618e-09 | -19.76 | CREBBP (CREB binding protein) | protein interactions | 1387 | 372 | 105 | 17029 | 2761 |
TCF12,CCNC,PTMS,ATXN3,TRERF1,FOXM1,TRIP10,RPS6KA1,PTTG1,MYH9,CSNK2A1,SMARCA4,IRF3,TAF6L,SND1,AP1B1,UBE2I,LYN,CREM,PAPOLA,RAD23A,MDM2,PCNA,CCNA2,ATG3,ZNF639,GMEB1,ANAPC7,CDC25B,MYBL1,ATF2,CARM1,SP3,KDM3B,GABPA,EID1,E2F3,NFATC2,BRCA1,TRIM28,DDX17,UBTF,BRMS1,MKNK1,CDC16,SMAD2,EIF4ENIF1,STAT6,MAFK,HIPK2,ARNTL,STAT1,KPNA2,NCOA1,H3F3A,SMAD1,MAPK1,SMAD4,POT1,HDAC2,PTOV1,NCOR2,EWSR1,TCF3,KLF13,WDR5,ETS1,FOXO3,CNOT3,RPA2,CENPJ,MBD2,MSH2,SS18L1,CREB1,CITED2,MAML1,CPSF4,STAT3,N4BP2,NCOA2,MSH6,KAT2A,MIER1,MYBL2,ANAPC2,ELK1,IRF5,POLR2A,MAPK3,NAP1L1,SERTAD2,ETS2,CDC27,CSK,TFDP1,PML,E2F1,HMGB2,DDX5,MAP3K5,YY1,RBBP4,CDK2,YWHAH |
| 2.628e-09 | -19.76 | LMNA (lamin A/C) | protein interactions | 4000 | 646 | 162 | 17029 | 2761 |
H2AFZ,NOP2,TMEM203,TAP1,TMEM109,CSNK2A1,UBE2Q1,SNRPD3,UBE2I,PAPOLA,PRNP,PCNA,PARPBP,PIK3R2,SRSF4,GPATCH1,RPF2,TRA2B,CRY2,NUP153,CISD2,EIF5,LRRC59,SENP1,SRPK2,CDC5L,ELOA,MKI67,BRCA1,ANLN,MCM2,SLC25A5,DHX15,ALG3,UBTF,LUC7L3,PPM1G,U2SURP,BAZ1B,ATP6V0C,ACTB,DNAJC30,SMAD1,RTN3,SSRP1,DDX42,C9orf78,PHB2,AGTRAP,CTCF,THRAP3,NPLOC4,LMNA,FAM192A,RB1,C4orf3,VMP1,MCM5,BANF1,EFTUD2,ARL6IP1,YBX1,OSTF1,EEF1D,FDFT1,HP1BP3,RPL6,SRSF5,VKORC1,MATR3,ISG15,MASTL,DERL1,SCARB2,MTHFD2,KPNA1,GALNT2,TMEM54,PIAS2,CTSA,RBBP4,CDK2,TMEM14A,APOL2,USP7,CYLD,WDYHV1,URB2,SF3B1,TOR1AIP1,TPX2,PMS2,SLC35B2,PCBP1,SDHA,RPL11,CRKL,HNRNPA2B1,AHCTF1,SIAH1,UCHL5,PPME1,CLN6,TMEM14C,PRPF19,MAPRE2,NARF,RNPS1,NUP155,GAR1,TRIM28,SERP1,EIF3G,TMEM201,SRSF1,SUGP1,TMEM41A,DUS3L,HNRNPR,H2AFX,LMBR1,CYBC1,FUS,SMURF1,CDS2,RPS2,ANXA6,CASP6,PDAP1,TMEM243,MRPS26,TFRC,SLC35B4,H2AFY,TAGLN2,FBL,UBE2M,SLC35A1,HNRNPM,NIPAL3,DDX24,PRKDC,WDR18,ILF3,RFXANK,RANGAP1,NEU1,DDX23,RPA1,KPNA4,TRIM26,SLC38A7,OSBPL8,MFAP1,FAM3C,PML,USP20,PKD2,DDX5,SRSF3,CD81,BYSL |
| 2.650e-09 | -19.75 | REACTOME_G1_S_TRANSITION | MSigDB lists | REACTOME_G1_S_TRANSITION | 106 | 41 | 17377 | 2626 |
POLA2,MAX,MCM10,CDT1,DBF4,CUL1,ORC1,CCNB1,PSMD9,FBXO5,RPA2,RB1,PSMD2,PCNA,PSMD1,PSMA6,CCNA2,MCM5,CDKN1B,ORC3,PRIM2,PSMB7,PSMA1,RRM2,CDC6,PKMYT1,MCM2,PSMB9,PSMB3,PSMC4,PRIM1,RPA1,PPP2CA,POLE,RPS27A,PSMD8,PSMD3,TFDP1,E2F1,CDK2,PSMC1 |
| 2.650e-09 | -19.75 | GNF2_HDAC1 | MSigDB lists | GNF2_HDAC1 | 106 | 41 | 17377 | 2626 |
ZNF207,DDX47,CDC40,ZCCHC8,SF3B1,EIF3D,SUMO2,NACA,GTF3A,SNRPD3,PAPOLA,SF3B2,NOL11,SRSF4,TRA2B,TARDBP,COPS7B,FBL,RBM15,HNRNPM,SRSF10,YTHDC1,SNRNP200,HNRNPF,PSMA1,UTP3,CBFB,DDX39A,DHX15,SRSF1,DAP3,HSPB11,HNRNPR,CSK,RBMX,U2SURP,SRSF3,BTF3,YY1,CCDC59,IFI16 |
| 2.696e-09 | -19.73 | protein localization to nucleus | biological process | GO:0034504 | 163 | 55 | 17256 | 2622 |
POLA2,TXN,NUP188,TSC2,PHB2,RAE1,TOR1AIP1,NUP54,SUPT7L,RPAIN,PARK7,LMNA,RPL11,CDK5,SNUPN,MDM2,SP100,XPA,NUP107,RPF2,TNPO2,TNPO3,NUP153,PIKFYVE,STAT3,NUP85,MORC3,PLK1,TGFB1,PPP3CA,SEC61B,NXT1,NOL8,INTS13,TOR1AIP2,NUP155,RANGAP1,TOPORS,NUTF2,PTTG1IP,PAF1,HHEX,KPNA4,KPNA1,OSBPL8,ARNTL,PML,PPP3R1,NUP62,KPNA2,DVL1,RRS1,NUP58,IPO4,NXT2 |
| 2.697e-09 | -19.73 | GO_NUCLEOTIDE_EXCISION_REPAIR | MSigDB lists | GO_NUCLEOTIDE_EXCISION_REPAIR | 110 | 42 | 17377 | 2626 |
SLC30A9,USP7,ATXN3,POLR2K,XAB2,SUMO2,CHD1L,UBE2I,NEIL2,RAD23A,RPA2,PCNA,XPA,RAD23B,COPS7B,TCEA1,AQR,GTF2H2,OGG1,PRPF19,COPS8,ERCC1,HMGN1,POLR2I,RFC3,POLR2L,POLR2G,POLK,RBX1,PPIE,POLR2D,RFC2,POLR2A,RPA1,POLE,POLR2J,RPS27A,NEIL3,COPS6,ZNF830,DDB1,RAD51D |
| 2.740e-09 | -19.72 | NEDD8 (neural precursor cell expressed, developmentally down-regulated 8) | protein interactions | 4738 | 255 | 79 | 17029 | 2761 |
ATXN3,HNRNPAB,RPLP2,MAGED1,CUL1,SDHA,RPL11,RPL23A,HNRNPA2B1,PSMA6,STRBP,TFG,COPS8,RPL35,RBX1,VHL,ELOA,CIRBP,HNRNPF,CUL3,NUP155,CLNS1A,DDX17,DNAJC10,HSPA4,HNRNPR,PRDX5,PPA2,RPLP1,KPNA2,ACTB,FUS,COPS6,USP11,SMURF1,TUBB,USP13,UBE2D3,EWSR1,UFC1,DHX9,TKT,BRAP,RPL15,FBXO3,DNAJC8,CTPS1,FEM1B,YBX1,AHCY,COPS7B,RPL19,PABPC1,UBE2M,SPTAN1,RPL8,ILF3,RPL6,RPS10,MEMO1,PSMA1,MATR3,PRDX1,HSPA1B,HGS,SYNCRIP,HNRNPH3,KLHL15,TFE3,KBTBD7,DCAF11,KHSRP,DDX5,YWHAZ,CDK2,HNRNPDL,IGBP1,HRAS,DDB1 |
| 2.747e-09 | -19.71 | GSE37534_UNTREATED_VS_GW1929_TREATED_CD4_TCELL_PPARG1_AND_FOXP3_TRASDUCED_DN | MSigDB lists | GSE37534_UNTREATED_VS_GW1929_TREATED_CD4_TCELL_PPARG1_AND_FOXP3_TRASDUCED_DN | 190 | 61 | 17377 | 2626 |
HIVEP3,RAB14,GCLM,PKP4,HJURP,FAM53C,UFC1,CENPF,YTHDC2,RACGAP1,KIF2C,NANS,DNAJB1,RGS2,TMEM165,POLR3K,WRB,HMG20A,RB1,NDUFB4,LRRC8D,SEC24C,KIF14,GTSE1,CTR9,KIF22,CITED2,PPA1,TACC3,ABCC5,RPAP3,PPP3CA,HMGN1,RFC3,CDC123,NSDHL,MRS2,KIF15,RTF1,AURKB,UBE4B,SMC2,USP22,SHCBP1,API5,KIF11,RPA1,RAD51C,HSPB11,BIRC5,MFAP1,RBMX,OAZ2,HMGB2,DDX5,YWHAZ,SPCS3,GALNT10,ARRB2,DDB1,POLQ |
| 2.747e-09 | -19.71 | GSE23695_CD57_POS_VS_NEG_NK_CELL_DN | MSigDB lists | GSE23695_CD57_POS_VS_NEG_NK_CELL_DN | 190 | 61 | 17377 | 2626 |
CCDC93,DDX47,UBN1,TRIP10,MANBA,SLC41A1,FAM53C,CDK2AP2,GADD45G,TMEM97,ASAH1,B4GALT1,STMN1,RPAIN,JMY,GTF2F1,PAIP2,TERF2IP,MOAP1,CCNK,FAM192A,CDKN2C,CYHR1,CLIC4,NDUFA2,DNAAF2,FIZ1,CS,AKR1B1,FAM76B,PLCL2,CITED2,ATF2,SAP30L,ARID4A,PLK3,TRAPPC9,GABPA,RB1CC1,TOP3A,SSR2,UBE4B,MCFD2,TOLLIP,CHCHD6,HSPA1B,ABHD5,MASTL,SEC23IP,BRD2,UAP1,ACYP1,PDRG1,ZHX1,CDCA5,ACLY,IDH3B,CLN3,FBXL3,PITRM1,ABCA1 |
| 2.747e-09 | -19.71 | GSE36476_CTRL_VS_TSST_ACT_40H_MEMORY_CD4_TCELL_YOUNG_DN | MSigDB lists | GSE36476_CTRL_VS_TSST_ACT_40H_MEMORY_CD4_TCELL_YOUNG_DN | 190 | 61 | 17377 | 2626 |
TMEM106C,POLA2,IMMT,TXN,MCM10,HJURP,NQO1,UCK2,TPX2,CDCA3,CDCA8,KIF23,RACGAP1,PXMP2,KIF2C,BLM,CCNB1,NCAPG,STMN1,MYL6B,SPAG5,SAC3D1,DTL,IRF4,PCNA,MCM5,DUT,PPCDC,TXLNA,CENPM,TALDO1,TK1,ASPM,MKI67,RRM2,NUSAP1,AURKB,BRCA1,MCM2,SLC25A5,KIF11,TARS,CHAF1A,SRSF1,ZNF282,SLCO4A1,TIMM13,PALB2,KIF18B,STT3A,BIRC5,CEP55,PTPN7,YWHAH,CCNB2,PGAM1,UBE2C,ESPL1,TUBB,BYSL,RAD51D |
| 2.772e-09 | -19.70 | SNRPD1 (small nuclear ribonucleoprotein D1 polypeptide) | protein interactions | 6632 | 142 | 52 | 17029 | 2761 |
USP7,SART1,CYLD,SF3B1,SUZ12,DHX9,TIA1,CUL1,SNRPD3,LMNA,SF3B2,HNRNPA2B1,SNUPN,EIF4A3,EFTUD2,YBX1,PTGES3,GEMIN4,EIF5,LUC7L2,HNRNPM,CDC5L,PRPF19,SRPK2,SNRNP200,SNRPB,SF3B6,CUL3,SREK1,LSM8,DDX20,PRPF3,MCFD2,LUC7L,TRIM28,SF3A2,CLNS1A,DDX23,SUPT16H,CAND1,GEMIN5,LSM6,DDX5,SNRPG,COPS6,SNRNP70,ARRB2,CD81,SMURF1,PDCD4,GEMIN7,PRPF4B |
| 2.807e-09 | -19.69 | DACOSTA_UV_RESPONSE_VIA_ERCC3_COMMON_DN | MSigDB lists | DACOSTA_UV_RESPONSE_VIA_ERCC3_COMMON_DN | 468 | 119 | 17377 | 2626 |
CCDC93,TCF12,UBL3,PNISR,ADAM10,UBR2,SUZ12,UCK2,CUL1,LYN,STAM,CHD1,PAIP1,ZNF804A,DST,ASAP2,NVL,UTP18,KIF14,RAD23B,ATP13A3,NUP153,TP53BP2,MYBL1,ATF2,TIPARP,MGAT5,ABI1,PTPRK,SRPK2,MKLN1,KLF10,SEPT9,NCK1,TLK1,E2F3,BRCA1,DHX15,KRIT1,KIF2A,PPP2CA,TRAM2,TAB2,CERS6,U2SURP,WDR7,OGT,RBMS1,NCOA1,FAM208A,XRCC4,TSPAN5,PARD3,NUMB,USP13,FUBP1,NCOR2,PKP4,CDS2,TRIP12,PPP1R12A,MECP2,TRIO,CENPF,TRAK1,MED13L,KIF23,MEF2A,CDK13,PAWR,PPP3CB,RAB6A,DCUN1D4,BLM,PARN,FOXO3,PIP4K2A,PTPN2,RB1,HOMER1,MBD2,FUT8,DAPK1,MSH2,FBXL7,AFF1,UPF2,CREB1,PIKFYVE,MTX2,FAM171A1,NCOA2,MICAL3,SOCS5,GINS1,IFRD1,PRIM2,NEK7,ZMYND11,ACSL3,RCOR1,FXR1,KIF11,KLF6,PICALM,NMT2,GOLGA4,CDC27,OSBPL8,PARG,BBX,MAPK6,LRPPRC,PKD2,RBPJ,SRSF3,NR2F2,ZMIZ1,TMEM131 |
| 2.833e-09 | -19.68 | HALLMARK_MITOTIC_SPINDLE | MSigDB lists | HALLMARK_MITOTIC_SPINDLE | 199 | 63 | 17377 | 2626 |
WASF2,KIF3B,MAPRE1,NF1,CENPF,TRIO,TPX2,MYH9,KLC1,KIF23,ARFIP2,RACGAP1,KIF2C,MYO9B,NOTCH2,CNTROB,RAPGEF6,TUBGCP2,SAC3D1,FBXO5,DST,KIF5B,SMC3,CDC42,CENPJ,PRC1,ARHGEF2,KIFAP3,KIF22,KNTC1,GEMIN4,ABI1,SMC4,SPTAN1,PLK1,STAU1,SEPT9,NCK1,NET1,TLK1,KIF15,TUBGCP5,EZR,NUSAP1,ARHGEF12,ANLN,KIF11,RHOT2,EPB41,TSC1,PCM1,MID1IP1,CDC27,BIRC5,LRPPRC,PKD2,ROCK1,SASS6,CCNB2,PDLIM5,ESPL1,ALS2,CSNK1D |
| 2.839e-09 | -19.68 | CHIANG_LIVER_CANCER_SUBCLASS_PROLIFERATION_UP | MSigDB lists | CHIANG_LIVER_CANCER_SUBCLASS_PROLIFERATION_UP | 164 | 55 | 17377 | 2626 |
HJURP,DEPDC1,FOXM1,B4GALT5,PTTG1,CENPF,TPX2,RMI2,KIF23,PTP4A3,RACGAP1,NUF2,KIF2C,TMED3,PM20D2,CCNB1,NCAPG,FANCI,FBXO5,DTL,OIP5,CCNA2,GLIS2,KIF14,PRC1,LDLRAD3,GPD1L,SMC4,ABCC1,ASPM,RAD51AP1,PBK,MKI67,CKAP2L,NUSAP1,CDC6,AURKB,GALNT7,LRRC1,MCM2,ANLN,SOX4,SHCBP1,KIF11,ATP1A1,KIF18B,BIRC5,CDCA7L,CEP55,CDCA5,HMGB2,SASS6,CCNB2,UBE2C,HDAC2 |
| 2.881e-09 | -19.66 | ZHANG_TLX_TARGETS_DN | MSigDB lists | ZHANG_TLX_TARGETS_DN | 87 | 36 | 17377 | 2626 |
DNAJC2,MCM10,CENPF,SMC6,BLM,NCAPG,TCF19,FANCI,SPAG5,DTL,LYAR,CCNA2,TIMELESS,TARDBP,SLC12A2,NUP85,SMC4,GINS1,NASP,RAD51AP1,NET1,MKI67,WDHD1,SMC2,BRCA1,ANLN,KIF11,SHCBP1,MASTL,PRIM1,SRSF1,RAD51C,POLE,RBL1,CEP55,SASS6 |
| 3.017e-09 | -19.62 | GSE9650_EFFECTOR_VS_MEMORY_CD8_TCELL_UP | MSigDB lists | GSE9650_EFFECTOR_VS_MEMORY_CD8_TCELL_UP | 186 | 60 | 17377 | 2626 |
PPIB,SMAP1,NDUFB6,GNPDA1,DAP,CDCA3,RRM1,CDCA8,KIF23,AGPAT3,ABCB10,SIRT2,MXD4,POMP,LACTB2,FKBP2,REEP5,REPS1,DTL,CDKN2C,IRF4,CCNA2,PRC1,FAM89B,BRD7,KIF22,TACC3,ELOF1,TMEM160,USO1,NASP,MIOS,PRIM2,SNX2,IDH3A,MKI67,GBA,MRPL43,ARHGDIB,AURKB,CCNF,ANLN,GNAS,JAK1,SURF4,BIRC5,TWSG1,PSMD8,CDCA5,MAP4,MRPL27,DBI,ARNTL,KPNA2,CTSA,HMGB2,RNF14,CDK2,CCNB2,ATP6V0E1 |
| 3.017e-09 | -19.62 | GSE369_SOCS3_KO_VS_WT_LIVER_UP | MSigDB lists | GSE369_SOCS3_KO_VS_WT_LIVER_UP | 186 | 60 | 17377 | 2626 |
CHMP2A,GNPNAT1,NOP2,NDUFB6,SUCLG1,MRPS15,PHB2,TMED3,RSAD1,HAUS2,PAPOLA,TFAP4,ERH,UTP18,CD3EAP,RNFT1,TIMM23,PPP1R8,RBM34,CS,NAA50,DDX31,MRPL11,OSTC,MINPP1,ORC3,MRPL21,GTF2H2,NUP85,TMBIM1,MRPL32,TMEM160,FYTTD1,RPP25,SRP72,IFRD1,ATP13A1,GUK1,AATF,WDR18,VDAC2,ABHD11,NUTF2,FOXRED1,TXNL4A,MRPS14,GFER,USP36,AKAP1,XRCC5,SDHB,MTHFD2,CCDC86,TTLL4,ITGB1,PIEZO1,RUVBL2,COPS6,RRS1,PDSS2 |
| 3.017e-09 | -19.62 | GSE22886_DAY1_VS_DAY7_MONOCYTE_IN_CULTURE_DN | MSigDB lists | GSE22886_DAY1_VS_DAY7_MONOCYTE_IN_CULTURE_DN | 186 | 60 | 17377 | 2626 |
FEZ2,SUCLG1,CASP6,MRPS15,PHB2,TOR3A,CUTA,HEXB,HMGN3,HAUS4,GTF3A,TMED3,REEP5,TFRC,HDDC2,EBP,MAN1A1,CDK5,SNRNP25,DUS4L,GOT2,MRPS27,MRPL34,HADHB,FAM89B,SEPT11,SUCLG2,TTC3,AHCY,IMPA2,SLC25A1,FDFT1,MOSPD1,LDHB,ABHD2,TIMP2,PPT1,PRKDC,DENND4C,KIAA0930,METTL5,ESYT1,MTX1,SLC25A5,ECH1,AMZ2,GNAS,PLD3,CCDC6,PTER,PRPS2,MPV17,ACAT1,COX5A,UQCRH,MDH1,ACADM,GPI,CHPT1,HIGD2A |
| 3.017e-09 | -19.62 | GSE41867_NAIVE_VS_DAY30_LCMV_CLONE13_EXHAUSTED_CD8_TCELL_DN | MSigDB lists | GSE41867_NAIVE_VS_DAY30_LCMV_CLONE13_EXHAUSTED_CD8_TCELL_DN | 186 | 60 | 17377 | 2626 |
HIVEP3,OTUD5,GLT8D1,SYS1,COPA,UBN1,FAM53C,SF3B1,CDK2AP2,CUTA,TMED3,FOXO3,RAB11A,PAIP2,EBP,UBE2Q2,ZNF420,NUP210,RABGAP1L,LPIN2,SLC44A1,TTC9C,TPST1,ATG13,RPN2,TECR,PDIA6,ATF2,N4BP2,TMEM9,TMED2,NIPAL3,PSRC1,ATG9A,RDH10,RFFL,USP22,SEPT7,CYFIP2,ECH1,DDX17,DERL1,GALNT2,NSF,TMED10,DUSP3,SNAP23,HNRNPH3,ERGIC3,PRDX5,FAM3C,UHRF2,VCPIP1,DMWD,EHD4,E2F2,CHPT1,ABCA1,TOB1,ESYT2 |
| 3.017e-09 | -19.62 | GSE557_CIITA_KO_VS_I_AB_KO_DC_DN | MSigDB lists | GSE557_CIITA_KO_VS_I_AB_KO_DC_DN | 186 | 60 | 17377 | 2626 |
KCTD7,IMMT,ZNF496,SMAP1,HNRNPAB,C16orf87,PMS2,EPN1,TOP2B,STAM,TUBGCP2,OIP5,FKBP1A,PSMD1,SLC1A4,PPP1R8,FIZ1,TTC9C,PPP6C,MRPS27,TPST1,CS,PCYT2,MAST2,METTL9,GPD1L,TMBIM1,HNRNPM,PRPF19,EIF5A,FYTTD1,SNX25,CYP20A1,MAP7D1,NUTF2,C9orf40,MEN1,EIF4G2,SYMPK,TMEM201,OPTN,DNAJC10,PCM1,RAD18,PSMD3,PTER,E2F4,PRPS2,NUP62,VPS4A,SMAD1,RBBP4,E2F2,MRPL3,CBX4,C7orf26,FAF1,DDB1,HDAC2,SSRP1 |
| 3.017e-09 | -19.62 | GSE17721_0.5H_VS_4H_PAM3CSK4_BMDC_UP | MSigDB lists | GSE17721_0.5H_VS_4H_PAM3CSK4_BMDC_UP | 186 | 60 | 17377 | 2626 |
MBD1,HSPH1,PARP12,GORASP1,HLA-E,MRPL39,DYNLL1,SNX15,TRIO,KLF13,ARFIP2,HCFC1R1,ATP6V1B2,GLRX3,C19orf48,HDDC2,FANCL,ZBTB45,CRAT,PELO,EI24,RPF2,MAVS,ALDH18A1,ALDH9A1,NIPSNAP1,CDC37,NOL12,PTPN18,TIMP2,KLF10,EID1,RAB7A,GALK2,MCFD2,ICAM2,TSR2,SUPT16H,CAT,PON2,HHEX,WAS,ATP6V1D,TIMM13,HINT1,TXNDC16,MFAP1,ACOX1,CDCA7L,FTSJ1,HMGB2,MBOAT1,ATF6,PDXK,SASS6,ARHGAP23,IGBP1,POT1,HRAS,RAB3IL1 |
| 3.017e-09 | -19.62 | GSE27786_CD8_TCELL_VS_ERYTHROBLAST_UP | MSigDB lists | GSE27786_CD8_TCELL_VS_ERYTHROBLAST_UP | 186 | 60 | 17377 | 2626 |
SEPHS2,RHOG,TRIP12,MRPL42,MPHOSPH8,DCAF15,PHF23,TOR3A,KLC1,CDK13,SIRT2,POMP,GYG1,WDR5,GLRX3,EXT2,GIT2,HMG20A,NDUFS7,RRP36,RNF103,NDUFS4,EBP,GTPBP3,CLUAP1,LRRC8D,ZDHHC13,LRRC59,NSUN4,TRIM14,CPNE1,UBQLN4,PPP3CA,DDX28,FAM172A,TSPYL4,NOL8,PCGF6,BCLAF1,EIF2A,LRRC1,STX16,NDRG3,PHF6,SOCS7,KRIT1,EIF3K,SGSH,BRD2,ACYP1,CORO1C,IARS2,SIL1,ADAM9,BTF3,PDSS2,TSPAN5,MRPL3,VPS29,PRPF4B |
| 3.094e-09 | -19.59 | YAP1 (Yes associated protein 1) | protein interactions | 10413 | 260 | 80 | 17029 | 2761 |
IMMT,COPA,SMARCA4,SND1,UBQLN2,SEC16A,PAPOLA,HNRNPA2B1,SPINDOC,PA2G4,PIN1,TTC9C,TP53BP2,AHCYL1,MCMBP,CSTF1,CCT2,SNRPB,WBP2,HNRNPF,WBP1,OGDH,SLC25A5,SUPT16H,DNAJC10,AHNAK,SMAD2,HSPA4,HNRNPR,MAP4,STAT1,ITGB1,ARRDC1,KPNA2,SMAD1,PFKP,PARD3,TUBB,HDAC2,FUBP1,HSPH1,UNK,SCAMP3,PHB2,SRSF6,RAE1,RPL15,RAPGEF6,ARID1B,VPS25,PSMD2,RPL17,RRBP1,ANXA5,H2AFY,YBX1,RPL19,CNN2,CREB1,EIF3L,ATP5IF1,CYFIP1,TK1,WDR1,RPL6,RTF1,ARID1A,MATR3,PRDX1,POLR2A,XRCC5,ADSS,EPRS,UPF1,PML,YWHAZ,UBE2C,IGBP1,YWHAH,SMARCD1 |
| 3.101e-09 | -19.59 | GO_RNA_LOCALIZATION | MSigDB lists | GO_RNA_LOCALIZATION | 173 | 57 | 17377 | 2626 |
TOMM20,CDC40,SARNP,NUP188,THOC1,RAE1,SRSF6,RBM8A,ALKBH5,NUP54,FLOT1,AGFG1,XPO7,PRPF18,NUP205,HNRNPA2B1,SNUPN,AHCTF1,NUP210,EIF4A3,ZNHIT6,SRSF4,NUP107,UPF2,NUP153,GLE1,FBL,CHTOP,MVP,ZC3H3,NUP85,SEH1L,SRSF10,SRSF11,EIF5A,FYTTD1,CCT2,NXT1,POLR2D,RNPS1,SLBP,NUP155,SRSF5,BUD13,DDX39A,RPSA,SRSF1,IWS1,HHEX,TSC1,UPF1,LRPPRC,KHSRP,NUP62,SRSF3,AAAS,NXT2 |
| 3.101e-09 | -19.59 | GSE17974_0H_VS_72H_IN_VITRO_ACT_CD4_TCELL_DN | MSigDB lists | GSE17974_0H_VS_72H_IN_VITRO_ACT_CD4_TCELL_DN | 173 | 57 | 17377 | 2626 |
INTS2,GALK1,CYTIP,IMMT,SKA3,TRIP10,RHOC,PDAP1,HNRNPUL2,CENPF,SND1,SNRPD3,BLM,COMMD8,KTN1,PARK7,MAD2L2,FBXO22,EBP,HNRNPA2B1,IRF4,CCNA2,CENPJ,MCM5,DUT,PPCDC,ARL6IP1,GLE1,DNMT1,TK1,KLF10,ERLIN1,CRNKL1,CCDC34,WDHD1,DNAJC9,PSMG1,VDAC1,CCNF,RFC2,FADD,ANKZF1,KIF2A,TRIM4,KEAP1,HSPB11,ZNF367,DBI,DNAJC17,PGRMC1,IARS2,COX8A,COX5A,DTD1,RUVBL2,NGLY1,FAF1 |
| 3.159e-09 | -19.57 | SRPK2 (SRSF protein kinase 2) | protein interactions | 6733 | 453 | 122 | 17029 | 2761 |
MIB2,SART1,TRIM41,UBE2E2,TXN,PNISR,NOP2,RPLP2,CHERP,CHD1L,ANK3,YTHDC2,RBM8A,ENSA,DHX8,USP39,PCBP1,APP,PABPC4,EPM2A,RBM23,EIF4A3,NSRP1,AP1M1,SRI,TRA2B,MAST2,FAM76B,AHCYL1,CHTOP,RBM15,CDK12,PDCL3,SRPK2,SNRPB,DRAP1,CUL3,RNPS1,SREK1,DIDO1,BUD13,LUC7L,ERC1,DHX15,USP36,EIF3A,SRSF1,SUPT16H,RPL37,DGCR8,CLK3,SAFB,LUC7L3,PPM1G,MAP4,ACTB,CHEK2,CLU,ARRB2,NGLY1,RPS26,NXT2,PRPF4B,PRPF38B,NSMCE4A,MAPRE1,TRIP12,ZFP91,SRSF6,VAV2,PRKAA1,CCM2,ARGLU1,HMGN3,CDK13,THRAP3,WDR5,MFSD10,CCDC28A,LMNA,SRXN1,HERC3,FGFR3,TNS3,DNAJC8,CTNNBL1,YBX1,PABPC1,HNRNPM,LUC7L2,RBM15B,YTHDC1,SRSF11,GCC2,PRRC2A,MAPKAPK3,CAMSAP1,GTPBP4,C1orf35,RTF1,BCLAF1,MAP7D1,SRSF5,RIT1,DDX39A,KIF11,MACF1,SLTM,MATR3,SNRPA,PHF6,XRCC5,HMGN2,CAND1,CCDC86,RBMX,C4orf46,ZRANB2,TCOF1,SRSF3,SNRNP70,MZT2B |
| 3.161e-09 | -19.57 | WANG_LMO4_TARGETS_UP | MSigDB lists | WANG_LMO4_TARGETS_UP | 330 | 91 | 17377 | 2626 |
UBL3,PIGM,MAX,ST13,TRAF7,PRKCSH,SLC2A1,MOGS,TMEM97,RMI2,STARD7,C5orf30,GLUD1,C19orf48,BCAP31,KRR1,NEK6,NT5DC1,MTA1,ETV6,SRSF4,ATP13A3,PDS5B,TTC3,TIPARP,OGG1,ANKRD9,ARL5A,USP34,CDC123,TLK1,RPL38,E2F3,NLN,SREK1,CDCA2,AZI2,CDC23,FOXRED1,USP36,TMEM201,HSPB11,HNRNPR,PDRG1,CCDC14,HIPK2,H2AFX,OGT,BCL7C,STK11,CAPN1,PDCD4,TUBB,RAD51D,FUBP1,ANKRD13D,PHB2,TCF3,MRI1,ARGLU1,PM20D2,CSNK1A1,ITGB5,SRRT,CFLAR,WWP2,SUB1,SNX18,ZNF326,AHCY,CREB1,CPSF4,LPCAT1,SLC35A1,FRMD8,NET1,NOA1,ARHGEF12,MTMR12,NDRG3,RHOB,CBX3,NAP1L1,ETS2,DBI,PPP3R1,PGRMC1,MEGF9,PITPNA,ZMIZ1,N4BP2L2 |
| 3.179e-09 | -19.57 | FBL (fibrillarin) | protein interactions | 2091 | 247 | 77 | 17029 | 2761 |
COX15,ZNF496,NOP2,SUZ12,EBNA1BP2,BRIX1,PABPC4,RPL11,TERF2IP,RBM23,NOL11,EIF4A3,UTP18,NOC2L,TARDBP,UTP4,FTSJ3,BAK1,NOL8,NSUN2,CUL3,DDX20,PRPF3,BRCA1,UTP3,CDC23,MCM2,VDAC1,DHX15,DDX17,TBC1D17,HNRNPR,RPS14,TBL3,RRS1,H3F3A,ARRB2,PDCD11,NIFK,RPS2,ZNF316,ZFP91,TCF3,CTCF,RPL15,LMNA,PNO1,YY1AP1,RPA2,DDX56,EIF2S2,RPL17,MCM5,BANF1,ZNF746,RPL19,AHDC1,GEMIN4,MAP3K14,TERF2,PHF10,DDX24,UTP15,GTPBP4,RPL6,RPS24,KRAS,KLF6,PHF6,RPA1,KPNA1,CCDC86,DDX5,RUVBL2,CDK2,GPATCH4,BYSL |
| 3.186e-09 | -19.56 | USP39 (ubiquitin specific peptidase 39) | protein interactions | 10713 | 93 | 39 | 17029 | 2761 |
SART1,HSPH1,SF3B1,DHX9,ARF1,APP,PA2G4,PCNA,PTEN,EFTUD2,MRM3,RPL22L1,SRSF10,CDC5L,PRPF19,SRPK2,SRSF11,SNRNP200,TRIM8,DDX24,NSUN2,SF3B6,LSM8,PRPF3,SRSF5,TXNL4A,GAR1,TSR2,DDX23,SUPT16H,CAND1,HSPA4,TRIM26,SAFB,ZRANB2,PRPF4,RUVBL2,SRSF3,PRPF4B |
| 3.241e-09 | -19.55 | GO_GOLGI_APPARATUS | MSigDB lists | GO_GOLGI_APPARATUS | 1368 | 284 | 17377 | 2626 |
TMED7,RAB14,GXYLT1,TSC2,ADAM10,ZDHHC8,AP3M2,TGOLN2,SYNRG,ASAP2,RABGAP1L,DNM2,AP1M1,AP2B1,TFG,MGAT5,RHBDD2,PGAP2,PLK3,SGCE,USO1,TMEM115,NRAS,RHOBTB3,AATF,ATG9A,GALNT7,MCFD2,SLC50A1,RAB2B,ARF4,TMED10,LIMK1,MYO18A,ST3GAL2,CHPF2,RTN3,B4GALT2,SVIP,MAPRE1,SCOC,GGA1,HLA-E,B4GALT1,SLC35B1,NOTCH2,TMED3,TMEM165,PSEN1,COPG2,PDXDC1,HAUS2,COPB2,CD59,RNF121,TPST1,PIKFYVE,LPCAT1,PPP6R1,TMED2,TERF2,NAGPA,GCC2,MAN1B1,MFNG,GTPBP4,ITM2A,GORASP2,GOSR1,MAP2K2,PSMB3,PI4K2A,SEC31A,CAT,OSBPL11,GOLGA2,NSF,ERGIC3,ARAP1,USP32,VCPIP1,SMPD4,PPP6R3,ZC3HAV1,SYS1,TRIP10,RAF1,RAC1,GPR89A,ANK3,VTI1A,SLC39A13,SLC35B2,AP1B1,PRKACA,APP,RAB21,CCNA2,TBC1D14,NSFL1C,GCC1,TMBIM1,ERF,GOPC,CUL3,ATP6V0A1,GORAB,PKMYT1,RAB1A,AP4E1,ERC1,GOLGA8A,CAMKMT,ATF6,B4GALT3,CSNK1D,SCAMP3,TMBIM4,B4GALT5,AGPAT3,RAB11A,HLA-A,CAPN2,GOLM1,PDCD10,ARF5,FUT8,AXIN2,ST8SIA2,NCOA2,MSH6,MOB4,PACS1,ZP3,PDE3B,MACF1,PICALM,SPPL2B,SH3GLB1,YIF1A,NUCB1,WNT5B,STX18,DBI,FAM3C,PARP10,GPR89B,SNAPIN,COPA,AGRN,CDIPT,BECN1,SEC16A,PRNP,RAB8A,CDC42,AP3S2,IMPAD1,RAB35,RP2,SLC35C2,DRAM2,SP3,APH1A,LAP3,NCK1,LRBA,PSMG1,CDC6,PITPNB,STX16,RHEB,OPTN,MAN2A2,GALNT10,ROCK1,CHEK2,CLU,CLN3,CHPT1,NAA60,LZTR1,AGTRAP,GORASP1,CIB1,SDC2,PCSK7,CDK13,RAB6A,B4GALT4,QSOX2,C1GALT1,XPA,PPIL2,EI24,KIFAP3,MDFIC,KDELR1,PREB,CYTH1,TRAPPC9,ACSL3,METTL22,ZDHHC3,NMT2,CAND1,GNAS,GALNT2,GOLGA4,ZDHHC7,GLT8D1,SART1,ASH1L,CORO7,GNPNAT1,SLC2A1,COPE,CLCC1,LYN,BCAP31,EXT2,ANKRD28,CSDE1,SAR1A,WDR44,AKAP8,PPP6C,LMAN1,CLTB,F2R,SCYL3,EBAG9,CLCN3,PPT1,RAB7A,BICD2,ATP1A1,SURF4,SCAP,UBXN2B,CANT1,AP1S1,MAPK1,CHID1,ABCA1,GOLIM4,GOLPH3L,SRGN,SCYL1,VPS45,CHIC2,ARFIP2,ARF1,GGA2,AP3S1,SCYL2,XPR1,MAN1A1,SPPL2A,FGFR3,STARD9,KLHL20,SEC24C,ZDHHC13,SLC35B4,ARHGEF2,DDX31,SLC35A1,MYO5A,B3GALT6,TGFB1,ZDHHC18,ATP2C1,COG1,RFFL,PNPLA8,MAPK3,HLA-B,SEC23IP,GOLGA7,SNAP29,GLG1,PREPL,HRAS |
| 3.293e-09 | -19.53 | MORF_ACTG1 | MSigDB lists | MORF_ACTG1 | 135 | 48 | 17377 | 2626 |
COX5B,RPLP2,SUMO2,NACA,RPL15,COX4I1,UBE2I,DAZAP2,RPL11,RPL23A,RPL17,YBX1,RPL19,RBM3,TAGLN2,PABPC1,LYPLA2,PCBP2,CFL1,RPL29,RHOA,SNRPB,RPL8,JTB,RPL38,LDHA,RPL6,RPS10,SSR2,RPS24,RPL27A,EIF4G2,RPS9,HMGN2,GNAS,RPL37,NAP1L1,HINT1,RPL32,RPS27A,RPS14,COX8A,RPLP1,ACTB,YWHAZ,BTF3,FAU,OAZ1 |
| 3.305e-09 | -19.53 | GSE39864_WT_VS_GATA3_KO_TREG_DN | MSigDB lists | GSE39864_WT_VS_GATA3_KO_TREG_DN | 182 | 59 | 17377 | 2626 |
UBL3,RMND5A,NCOR2,PPIB,MIF4GD,MRPL42,ADD1,CDK2AP2,UROD,DHX9,KIF23,ASAH1,MAN2B1,UBE2I,RUFY1,WDR48,APLP2,SNRNP25,GRSF1,MCM5,PHTF1,ADCY9,FUT8,FAM89B,RPF2,CORO1A,SPTSSA,AHCYL1,PHKG2,ALDH9A1,TMEM160,MLST8,SPTAN1,MLEC,ERMP1,BRD4,RNASEH2C,SIGMAR1,CREG1,BTG2,PPP1R21,MKI67,GLO1,GALK2,HAGH,CYB5A,SH3BP5,GNA12,PON2,TRIM47,SYNCRIP,ACLY,PKD2,ACADM,FAU,IGBP1,PTDSS1,HIGD2A,DDB1 |
| 3.343e-09 | -19.52 | WWOX (WW domain containing oxidoreductase) | protein interactions | 51741 | 256 | 79 | 17029 | 2761 |
H2AFZ,XAB2,SF3B1,CSNK2A1,SMARCA4,USP39,SNRPD3,PABPC4,SF3B2,CSDE1,FARSA,MDM2,EIF4A3,TARDBP,SMARCE1,RPRD1B,DVL2,SRSF10,CDC5L,KDM3B,CCT2,SNRNP200,POLR2G,WBP2,HNRNPF,EZR,PRPF3,BRCA1,WBP1,DIDO1,TRIM28,DHX15,EIF3A,DDX17,GEMIN5,KIF2A,HSPA4,HNRNPR,LUC7L3,PRDX5,U2SURP,OGT,FUS,DVL1,ZNF598,COIL,LONP2,PPIB,GORASP1,DHX9,THRAP3,PDCD7,LMNA,FBRS,HUWE1,SEC24C,CAPZA1,PABPC1,PREB,RPAP3,CYFIP1,RPRD1A,PRRC2A,SF3B6,RPL6,CYFIP2,SYMPK,PATL1,SF3A2,MATR3,POLR2A,SEC23IP,RBMX,HNRNPH3,ACLY,KHSRP,YWHAZ,SRSF3,WDR91 |
| 3.365e-09 | -19.51 | membrane organization | biological process | GO:0061024 | 791 | 181 | 17256 | 2622 |
NUP188,AGRN,TAP1,TGOLN2,AGFG1,CCNB1,SEC16A,ATP5PF,BECN1,NAPG,RAB8A,NUP210,NEK6,CDC42,DNM2,AP2B1,NUP153,TFG,SEH1L,TIMM50,PLK1,BAK1,SGCE,USO1,AKT2,AURKB,MCFD2,SLC25A5,STX16,STOML2,TRAM2,TIMM13,TMED10,RPS27A,GRIPAP1,TIMM29,MYO18A,ACTB,CLU,DVL1,VPS4A,CLN3,TFDP2,ARRB2,C2CD5,AAAS,GORASP1,NKD2,EPN1,LMNA,NUP205,CD59,ARPC5,SNX18,BANF1,ARL6IP1,BCL2,GLTP,SYTL3,NUP85,PPP6R1,TMED2,PREB,ABCC1,ATP5IF1,TRAPPC9,ADRB2,ARPC1A,GOSR1,SEC31A,SCARB2,FNTA,GOLGA2,NSF,SNAP23,PPP3R1,VCPIP1,NUP62,YWHAZ,ATP5F1A,PPP6R3,TMEM14A,CCNB2,NUP58,RHOG,NDC1,CHMP2A,TOMM20,IMMT,REPS2,TRIP10,DYNLL1,TOR1AIP1,ANK3,ACTR3,RAC1,VTI1A,MYH9,BCL2L1,STAM,REPS1,MIEF1,MOAP1,ANKRD28,UBXN2A,ANKLE1,ATP2A2,SH3BP1,SAR1A,NUP107,PPP6C,NSFL1C,TAP2,TARDBP,TP53BP2,APOOL,CLTB,LMAN1,ATF2,DVL2,DCTN1,CHP1,PPIF,ANKLE2,PPT1,RAB7A,CUL3,NUP155,CHMP2B,RAB1A,TAZ,PEF1,SERP1,CHCHD3,PPP2CA,HSPA4,CHMP4A,UBXN2B,CHMP4B,SMURF1,REEP4,AP2S1,EYA2,ABCA1,CSNK1D,GOLPH3L,RAE1,FLOT1,NUP54,ATP5F1B,RAB11A,WRB,TFRC,PIP5K1C,PTEN,SEC24C,SGCB,STAT3,RHOA,RABIF,HEBP2,ATP5MF,RHOT1,RHOT2,PICALM,CHCHD6,SH3GLB1,MFN2,LEMD2,SEC23IP,HGS,PDCD6,ELMO1,ATP5MC3,SNAP29,STX18,TFDP1,E2F1,YWHAH,CHMP7,SNAPIN |
| 3.421e-09 | -19.49 | DCUN1D1 (defective in cullin neddylation 1 domain containing 1) | protein interactions | 54165 | 230 | 73 | 17029 | 2761 |
TXN,HNRNPAB,RPLP2,KLHL18,CUL1,SNRPD3,DAZAP2,GLRX3,SDHA,PABPC4,RPL23A,HNRNPA2B1,STRBP,SOCS6,TP53BP2,TFG,ASB6,CSTF1,COPS8,SNRNP200,RBX1,VHL,SNRPB,HNRNPF,CUL3,DNAJC9,AURKB,SLC25A5,DHX57,DNAJC10,SMAD2,FUS,SNRPG,KLHL42,COPS6,MAPK1,TUBB,EWSR1,RPS2,DNAAF5,DHX9,TIA1,RPL15,TUT4,DDX56,ARHGEF1,ZNF326,FEM1B,RBM3,COPS7B,PABPC1,UBE2M,SOCS5,POLR2I,RHOA,ILF3,RPL6,RPS10,EIF4G2,API5,PRDX1,POLR2A,HSPA1B,MAPK3,CAND1,SYNCRIP,PRDX3,HNRNPH3,KLHL15,DDX5,SNRNP70,HNRNPDL,DDB1 |
| 3.448e-09 | -19.49 | rRNA metabolic process | biological process | GO:0016072 | 286 | 82 | 17256 | 2622 |
SART1,DDX47,RPLP2,NOP2,EBNA1BP2,RPL23A,KRR1,RPL11,UTP25,PA2G4,NOL11,CD3EAP,EIF4A3,UTP18,EXOSC1,RPF2,UTP4,FTSJ3,MRM2,RPP25,RPL29,RPL35,EXOSC6,NOL8,RPL38,UTP3,GAR1,RPS9,MAK16,RPSA,DDX17,RPL37,NSA2,RPS27A,LSM6,TBL3,RPS14,RPLP1,RNASEL,RRS1,PDCD11,RPS26,CSNK1D,RPS15,NIFK,RPS2,RRP15,RPL15,GTF3A,PNO1,RRP36,KRI1,LYAR,DDX56,EXOSC7,RPL17,PELO,RPL19,GEMIN4,POLR1B,FBL,NSUN4,MRM3,GTF3C6,TRIR,WDR18,TEX10,RPL6,RPL8,UTP15,RPS10,GTPBP4,RPS24,EXOSC9,BMS1,RPL27A,TSR2,RPL36,UTP20,RPL32,BYSL,DDX52 |
| 3.449e-09 | -19.49 | GSE22886_UNSTIM_VS_IL2_STIM_NKCELL_DN | MSigDB lists | GSE22886_UNSTIM_VS_IL2_STIM_NKCELL_DN | 191 | 61 | 17377 | 2626 |
BCCIP,NUP188,MCM10,HNRNPAB,MRPL39,CDK2AP2,CDT1,TMEM97,UCK2,EBNA1BP2,BCL2L1,BLM,RAD23A,PA2G4,PCNA,PSMD1,IARS,PRC1,NUP107,ALDH18A1,ORC3,CLN6,UBE2M,CDC37,CCT2,MLEC,NASP,SNRPB,WDR1,ABCF2,DNAJC9,CDC6,MCM2,SHCBP1,DDX39A,STK17B,CCT8,TRIM28,MAT2A,XRCC5,STOML2,EPRS,SLCO4A1,ATP1A1,CDCA4,SYNCRIP,DDOST,PRDX3,TFDP1,H2AFX,PTPN7,SLC16A1,KPNA2,PRPF4,SMG9,RRS1,MRPL3,ESPL1,BYSL,TUBB,IPO4 |
| 3.449e-09 | -19.49 | GSE22886_UNSTIM_VS_IL15_STIM_NKCELL_DN | MSigDB lists | GSE22886_UNSTIM_VS_IL15_STIM_NKCELL_DN | 191 | 61 | 17377 | 2626 |
WSB2,MCM10,HNRNPAB,MRPS15,MRPL39,CDT1,CDK2AP2,TMEM97,NIPA2,EBNA1BP2,BCL2L1,ORC1,BLM,GLRX3,POLR3K,NUP205,BCAT2,PRNP,DTL,PA2G4,PCNA,SLC1A4,IARS,SUV39H2,MCM5,PRC1,DNMT1,UBE2M,MSH6,SMC4,CCT2,MLEC,NASP,WDR1,RAD51AP1,SNRPB,NSDHL,PBK,DNAJC9,CDC6,NUTF2,VDAC1,MCM2,FANCE,CCT8,MAT2A,PSMC4,STOML2,XRCC5,SLCO4A1,EPRS,ATP1A1,PRDX3,CORO1C,TFDP1,PGRMC1,H2AFX,KPNA2,SNRPG,CDK2,HDAC2 |
| 3.481e-09 | -19.48 | MORF_MTA1 | MSigDB lists | MORF_MTA1 | 99 | 39 | 17377 | 2626 |
TMEM106C,KARS,MRPL9,NUP188,HNRNPAB,PDAP1,RAC1,DCTN2,ENSA,SLC4A2,RAB6A,XPO7,AP3S1,SDHA,BCAP31,CNOT3,NDUFV1,MTA1,BANF1,RAD23B,CS,CYC1,TCEA1,MAML1,SLC35A1,KDELR1,SNRNP200,POLR2I,NSDHL,TUFM,MAP2K2,SERP1,SNRPA,RPA1,PPM1G,COX5A,NUP62,COIL,HDAC2 |
| 3.484e-09 | -19.48 | RAD51 (RAD51 recombinase) | protein interactions | 5888 | 131 | 49 | 17029 | 2761 |
BCCIP,NSD3,SIRT2,PPP3CB,BLM,UBE2I,HMG20A,CDC73,TUBGCP2,WDR48,TERF2IP,HNRNPA2B1,RFWD3,PCNA,BABAM2,CDC42,PARPBP,XRCC2,MSH2,PDS5B,RNASEH2A,MCPH1,MSH6,POLK,RAD51AP1,USP10,BRCA1,USP21,RAD54B,RPA1,CXXC4,RAD51C,KEAP1,TIMM13,PALB2,RAD18,CHD3,E2F4,EIF2D,PML,H2AFX,UHRF2,E2F1,CAB39,XRCC3,IGBP1,LRP8,CBX4,RAD51D |
| 3.496e-09 | -19.47 | Influenza Infection | REACTOME pathways | R-HSA-168254 | 157 | 56 | 10287 | 1696 |
RPS15,NDC1,RPS2,NUP188,RPLP2,POLR2K,RAE1,NUP54,RPL15,NUP205,GTF2F1,RPL11,RPL23A,NUP210,RPL17,GRSF1,NUP107,NUP153,RPL19,CPSF4,NUP85,RPL22L1,SEH1L,TGFB1,RPL29,RPL35,POLR2I,POLR2L,POLR2G,RPL8,RPS10,RPL38,POLR2D,RPL6,RPS24,NUP155,RPL27A,RPS9,ISG15,POLR2A,RPSA,RPL36,RPL37,KPNA4,KPNA1,POLR2J,RPL32,RPS27A,RPS14,RPLP1,NUP62,KPNA2,FAU,RPS26,NUP58,AAAS |
| 3.606e-09 | -19.44 | GNF2_MCM4 | MSigDB lists | GNF2_MCM4 | 52 | 26 | 17377 | 2626 |
GINS1,RFC3,NASP,FOXM1,ASPM,RAD51AP1,RRM1,CDCA8,RRM2,RACGAP1,AURKB,MCM2,KIF11,FANCI,ASF1B,PA2G4,PCNA,CCNA2,KIF18B,MCM5,KIF14,CENPM,CCNB2,UBE2C,ESPL1,SMC4 |
| 3.613e-09 | -19.44 | GSE12366_GC_BCELL_VS_PLASMA_CELL_UP | MSigDB lists | GSE12366_GC_BCELL_VS_PLASMA_CELL_UP | 178 | 58 | 17377 | 2626 |
TMEM106C,USP7,NOP2,URB2,C16orf87,RMI2,SMARCA4,TOP2B,S1PR2,UBE2I,ETS1,QSOX2,RPAIN,FERMT3,CRKL,PHC2,CALM2,VASP,PCNA,ADD3,CCP110,IARS,PTEN,ARPC5,KIF22,OSTF1,CTDSP2,IMPA2,USP34,GINS1,PPP1R18,ETV3,GMFB,KCTD20,ADSL,C9orf40,MCM2,KDM1B,ARMC8,GAR1,SNRPA,SUPT16H,DDX23,MASTL,NAP1L1,CDCA4,FNTA,CDCA5,FAM126A,KPNA2,ROCK1,YY1,TMEM159,UBE2C,MYL12B,POT1,ESPL1,C7orf26 |
| 3.640e-09 | -19.43 | GSE9601_UNTREATED_VS_PI3K_INHIBITOR_TREATED_HCMV_INF_MONOCYTE_UP | MSigDB lists | GSE9601_UNTREATED_VS_PI3K_INHIBITOR_TREATED_HCMV_INF_MONOCYTE_UP | 165 | 55 | 17377 | 2626 |
ANXA6,CXXC1,MUM1,SNX15,TPX2,CDCA8,MYH9,SECISBP2,IRF3,KIF2C,SRRT,GIT2,TUBGCP2,MXD1,GTF2F1,SF3B2,RFWD3,MED8,BDH1,DDA1,ARHGEF1,MEA1,YBX1,NDUFS8,CORO1A,DNMT1,FRMD8,CSNK1G2,PPP1R9B,POLR2L,CSRP1,RNASEH2C,TACC1,RPL38,EZR,LRRC8A,BRCA1,WBP1,MBD3,H2AFV,MAP2K2,USP36,PSMC4,MYO1F,HMGN2,SERF2,DSN1,BIRC5,ZC3H7B,MYO18A,CHMP4B,NDUFS5,EHD4,RPS26,SSRP1 |
| 3.674e-09 | -19.42 | HAHTOLA_MYCOSIS_FUNGOIDES_CD4_DN | MSigDB lists | HAHTOLA_MYCOSIS_FUNGOIDES_CD4_DN | 107 | 41 | 17377 | 2626 |
SLC12A7,MRPL9,PPP1R2,NACA,YTHDC2,RBM8A,OLA1,UBQLN2,METTL3,FAM8A1,KTN1,PCYOX1L,ADD3,CDC42,IL6ST,ATIC,DUT,TTC3,TARDBP,MDFIC,EBAG9,USP34,SRP72,TSPYL4,ZBED5,GORASP2,PITPNB,CDC23,ICAM2,PRMT2,TRIM28,NAP1L1,HINT1,SYNCRIP,OSBPL8,LUC7L3,LY75,CD81,MRPL3,ZC3HAV1,FUBP1 |
| 3.694e-09 | -19.42 | RPL27 (ribosomal protein L27) | protein interactions | 6155 | 147 | 53 | 17029 | 2761 |
RPS15,COX15,RPS2,CYLD,NDUFS1,RPLP2,MECP2,DHX9,RPL15,CUL1,EBNA1BP2,BRIX1,PABPC4,RPL11,RPL23A,PA2G4,DDX56,PTEN,HUWE1,FUT8,RTCB,NOC2L,RPL19,PABPC1,HNRNPM,RPL35,RPS10,RPL6,GTPBP4,CUL3,ILF3,RPL8,RPL38,RPS24,BRCA1,VDAC1,MCM2,RPL27A,GAR1,RPS9,RPSA,CAND1,RPL36,RPL37,NSA2,RPL32,RPS14,QARS,RPLP1,RRS1,CDK2,CD81,RPS26 |
| 3.708e-09 | -19.41 | GO_RIBONUCLEOTIDE_BINDING | MSigDB lists | GO_RIBONUCLEOTIDE_BINDING | 1768 | 353 | 17377 | 2626 |
RAB14,ABCC10,TAP1,DHX8,GLUD1,UBE2I,EEF2K,KIFC1,CDK5,NEK6,RAB4A,ATP13A3,PDS5B,DNM2,SUCLG2,UPRT,MAST2,PLK3,RHOBTB3,NRAS,AKT2,PBK,MKI67,KIF15,DDX20,AURKB,SMC2,MCM2,RFC2,RAB22A,RAB2B,ARF4,MAP3K4,MKNK1,KIF18B,LIMK1,MYO18A,RNASEL,LONP2,PFKP,DDX42,DDX58,HSPH1,RECQL,CHTF18,RHOC,GSPT2,PRKAA1,TRIO,CERK,RRM1,RAB23,DHX9,KIF23,TOP2B,EIF2AK4,RTKN,DDX56,SMC3,MCM5,EFTUD2,MSH2,DAPK1,PIKFYVE,GNAI2,PHKG2,UBE2QL1,CARS2,DDX28,MAPKAPK3,NOA1,DHX29,PGS1,TYW1,PIP4K2C,GTPBP4,SEPT8,RIT1,ABCF1,MAP2K2,CCT8,RHOB,PI4K2A,XRCC5,ADSS,EPRS,NSF,CSK,QARS,DCK,CSNK1G1,ACLY,MAP3K5,CDK2,NRBP1,ACSF2,RHOG,KARS,ABCA3,TP53RK,RAB11B,RPS6KA1,RAF1,RAC1,CHD1L,ACTR3,KIAA0232,OLA1,TPX2,MYH9,PRKACA,FLAD1,PRKD3,RAB21,ATP2A2,RALB,UBA5,ADCY9,CLCN6,SEPT11,TAP2,ARL5A,CDK12,ADCY7,CCT2,ULK3,ATP13A1,TAOK1,MAP4K4,PFKFB3,GALK2,DNAJA1,PKMYT1,RAB1A,DHX57,MAT2A,DDX17,KIF2A,RAD51C,HSPA4,JAK1,RAB24,HIPK2,CBWD1,PDXK,PPP5C,CSNK1D,TUBB,DYNC1LI2,RHEBL1,POLQ,PRPF4B,GALK1,ANXA6,IP6K2,BLM,IFT27,PMVK,RAB11A,PIP5K1C,SRXN1,GATC,CBWD2,ARF5,MAP3K14,TTLL12,UBE2M,MSH6,SMC4,PDPK1,TK1,GUK1,DDX24,NEK7,BMS1,RHOT1,DDX39A,GUF1,KIF11,MARK2,MYO1F,GNA12,KIF18A,TTLL4,MAPK6,ASNA1,DDX5,DDX52,UBE2E2,DDX47,YTHDC2,MCCC1,UBE2Z,UBE2Q1,CSNK2A1,ABCB10,KIF2C,MAPK14,PAPOLA,ABL2,RAB8A,RAP1A,CDC42,EIF4A3,RAB35,TRMU,XRCC2,KIF22,RP2,EIF5,SRPK2,ABCC5,PLK1,LARS,SNRNP200,SEPT9,HARS,TLK1,CDC6,RAB5B,STK17B,LSG1,DHX15,RHEB,SEPT1,CHD3,IARS2,BAZ1B,QRSL1,STK11,ACTB,ROCK1,CHEK2,VPS4A,PSMC1,UBE2D3,SEPHS2,CDK13,RAB6A,THRAP3,CHKA,UBE2Q2,KIF13B,ALDH18A1,N4BP2,CSNK1G3,ABCC1,NTPCR,CREG1,AACS,ACSL3,MAP4K3,KRAS,EIF2AK1,UBE4B,SEPT7,BBS12,DAPK3,MASTL,PSMC4,GNAS,PRPS2,NLRC5,RUVBL2,MYO9A,EHD4,SUCLG1,UGP2,UCK2,PMS2,RRAGC,UCK1,SMARCA4,CHKB,ORC1,ATP6V1B2,TWF2,LYN,CHD1,FARSA,PDK2,IARS,SAR1A,NVL,KIF14,SCYL3,ACSL5,CLCN3,RAB7A,ARL5B,RAD54B,IDE,ATP1A1,DHX16,CLK3,STK38,FASTK,XRCC3,MAPK1,ABCA1,RAD51D,KIF3B,NADSYN1,SHPRH,TOR3A,SCYL1,GNE,ARFIP2,SMC6,ARF1,MYO9B,CDK11B,CSNK1A1,SCYL2,GFM2,PIP4K2A,WRNIP1,GTPBP3,KIF5B,FGFR3,STARD9,GART,NDUFV1,DDX31,ABCD1,CAMK2G,MYO5A,CSNK1G2,RHOA,BTAF1,PRKDC,HELB,ABCF2,ATP2C1,PRKAR1B,TUFM,PNPLA8,RHOT2,CDK11A,TARS,HSPA1B,MAPK3,MFN2,DDX23,RAB18,NEK1,UPF1,ATAD2,UBE2C,RPS6KC1,HIPK3,HRAS,TYW1B |
| 3.795e-09 | -19.39 | GSE42021_TREG_PLN_VS_CD24HI_TREG_THYMUS_DN | MSigDB lists | GSE42021_TREG_PLN_VS_CD24HI_TREG_THYMUS_DN | 187 | 60 | 17377 | 2626 |
C9orf78,NSMCE4A,MCM10,ADD1,XAB2,DAP,CDT1,CDK2AP2,CERK,MAN2B1,MXD4,AP1B1,GGA2,RGS2,FOXO3,REEP5,TMEM179B,MAT2B,TBC1D22A,RAB4A,ATP6V0A2,NDUFB9,RPL19,SLC38A10,TALDO1,CLN6,SLC35A1,ATP6V0D1,SRPK2,CSNK1G2,SEC61B,PTPN18,GUK1,PPP1R21,UBE4B,OGDH,RIT1,WDR81,COMMD4,SLC50A1,ECH1,MAPK3,EIF3K,SDHB,LEMD2,GNAS,TRIM47,GNA12,FNTA,ATP6V1D,CSK,ACOX1,QARS,CDCA7L,PIAS2,WIPI2,MZT2B,HRAS,CBX4,PTOV1 |
| 3.795e-09 | -19.39 | GSE21063_3H_VS_16H_ANTI_IGM_STIM_NFATC1_KOBCELL_DN | MSigDB lists | GSE21063_3H_VS_16H_ANTI_IGM_STIM_NFATC1_KOBCELL_DN | 187 | 60 | 17377 | 2626 |
MIF,NADSYN1,GPR132,H2AFZ,HJURP,ZCCHC8,ARID2,C1orf112,TRIO,DBF4,TPX2,CDCA3,CERK,RACGAP1,SNN,NUP205,DDRGK1,RPL23A,TFAP4,ANKLE1,SNRNP25,FBXL6,KIF14,PRC1,NDUFS8,KNTC1,TMEM14C,POC5,PCBP2,PREB,MLST8,SRSF11,PTPN18,NXT1,TSTA3,DHX29,DCAF8,MKI67,CKAP2L,ELP4,GORASP2,SMC2,ANLN,BORA,SERP1,USP36,NAP1L1,POLE,CERS6,FAM110A,ZNF689,UHRF2,SAMD8,SSNA1,DVL1,WDR62,E2F2,UBE2C,LRP8,NUDT3 |
| 3.864e-09 | -19.37 | MOOTHA_PGC | MSigDB lists | MOOTHA_PGC | 395 | 104 | 17377 | 2626 |
NDUFA5,NDUFB6,SUCLG1,TSC2,FOXM1,TMEM41B,MRPL39,PIGQ,MDH2,UQCR10,UROD,STARD7,TWF2,SLC20A1,SDHA,PSMA6,TIMM23,GRSF1,MRPL34,CS,HADHB,GPX4,VPS13B,GABPA,IDH3A,LRBA,PSMB7,RRM2,LRP5,ZFAND5,SLC25A5,ABHD5,DPYSL3,NECAP2,ATP1A1,TIMM13,ACYP1,DHX16,TIMM17A,FASTK,PPM1G,CAB39,PDXK,MRPL13,PFKP,SLC12A7,COX5B,NDUFV2,PHB2,MRPS2,RRM1,AGPAT3,CYCS,JMJD6,CRLF3,TFRC,DNAJB9,SAC3D1,FBRS,MAT2B,SLC31A1,CRAT,PCYT2,MRPL40,CYC1,MRPL11,MTX2,RNF5,LDHB,IFRD1,EIF3L,TIMM8B,GUK1,TUFM,LDHA,GTPBP4,TBRG4,ADSL,EIF2AK1,RANGAP1,MTX1,TOMM40,ABCF1,RXRB,AKAP1,ADSS,SDHB,ATP6V1D,PDCD6,MTHFD2,HSPBP1,PRDX3,NSF,DBI,COX8A,LRPPRC,ACADM,RUVBL2,GPI,NDUFS5,CHMP7,PGAM1,IFI16,EGLN1 |
| 3.889e-09 | -19.37 | PML (promyelocytic leukemia) | protein interactions | 5371 | 248 | 77 | 17029 | 2761 |
USP7,TOMM20,ATXN3,NF1,SUZ12,SUMO2,CUL1,CSNK2A1,SMARCA4,UBE2I,MAP1LC3B,MAPK14,PCBP1,PARK7,MXD1,RPL11,TERF2IP,SAP130,MDM2,SP100,SIAH1,GLIS2,TIMM23,PIN1,TBC1D14,DNM2,ATF2,SENP1,RBX1,GOPC,ATXN1,TOPORS,HHEX,SMAD2,DSN1,JAK1,E2F4,TULP3,AXIN1,HIPK2,STAT1,H2AFX,CHEK2,H3F3A,USP11,MAPK1,HDAC2,CSNK1D,NCOR2,NDUFS1,PAWR,TOP2B,WDR5,LMNA,FBXO3,RB1,KLHL20,NDUFA2,INTS7,HDAC7,BCL2,STAT3,NCOA2,KRAS,ATP5MF,PKM,MAPK3,FAS,PIAS2,SIAH2,PML,NANP,PLOD3,CDK2,WDR45B,IFI16,CDKN2A |
| 4.066e-09 | -19.32 | cellular amide metabolic process | biological process | GO:0043603 | 702 | 164 | 17256 | 2622 |
MRPS15,HEXB,MCCC1,EIF1B,BECN1,RBM4,MRPL19,PARK7,PABPC4,EEF2K,RPL23A,EIF5,SPTSSA,MRPL32,MRPL57,LARS,HARS,APH1A,MRPL43,MRPL12,EIF3A,RPL37,GEMIN5,RPS27A,RPS14,MRPL27,EIF2D,IARS2,QRSL1,CLU,DHFR2,CLN3,MRPL13,RPS26,ZNF598,RPS15,MRPL9,MRPS2,DHPS,GSPT2,CERK,PCSK7,RPL15,ASAH1,PM20D2,PSEN1,MCTS1,EIF2S2,ATIC,EFTUD2,MRPL40,MRPL48,MRPL21,PABPC1,PPA1,EEF1D,CARS2,EIF5A,EIF3L,ATP5IF1,CPQ,DHX29,NOA1,RPL6,RPS10,GBA,RPS24,MRPL16,EIF2A,EIF4H,EIF4G2,ABCF1,RPL36,EPRS,MTHFD2,ORMDL2,QARS,SAMD8,SMPD4,MRPL3,MMACHC,KARS,CYLD,RWDD1,RPLP2,MRPL39,EIF3D,NIT2,EFL1,PAIP1,RPL11,SEC11A,MRPL50,FARSA,IARS,MRPL34,MRPS27,CLN6,GM2A,HTRA2,RPL29,RPL35,RPL38,NLN,GLO1,NDUFA7,POLG2,MRPS14,EIF3G,RPS9,RPSA,EIF3H,EIF3K,PPP2CA,MRPL2,DAP3,IDE,MRPL55,CERS6,CHCHD1,FTSJ1,RPLP1,PPA2,B4GALT3,LTA4H,PDF,GCLM,RPS2,MRPL42,AGO2,MRPS26,SECISBP2,CHAC2,GFM2,SPPL2A,GSTK1,GART,CLIC4,GATC,ITGB8,RPL17,PELO,RRBP1,MRPL54,LTN1,RPL19,ST8SIA2,MRPL11,GTF2H2,RPL22L1,GALC,TUFM,RPL8,MRPS10,HAGH,RPL27A,GUF1,SPPL2B,NEU1,TARS,SLC19A1,RPL32,SPCS3,CPEB2 |
| 4.109e-09 | -19.31 | GNF2_MCM5 | MSigDB lists | GNF2_MCM5 | 59 | 28 | 17377 | 2626 |
GINS1,POLA2,NASP,HNRNPAB,SUZ12,RRM1,CDCA8,SLBP,MCM2,DHX15,SRSF1,DTL,PA2G4,PCNA,HSPB11,RBMX,MCM5,DUT,U2SURP,SRI,TRA2B,NUP62,NUP153,HMGB2,CENPM,SNRPG,SMC4,SSRP1 |
| 4.114e-09 | -19.31 | HIST1H1A (histone cluster 1 H1 family member a) | protein interactions | 3024 | 180 | 61 | 17029 | 2761 |
RPS15,NIFK,RPS2,SUZ12,SF3B1,CTCF,NSD3,EBNA1BP2,WDR5,CCNB1,PARN,CDC73,PABPC4,LMNA,SF3B2,KRR1,TERF2IP,KRI1,PA2G4,CCNA2,RBM34,ZNF746,H2AFY,CTR9,CDKN1B,RPF2,NAP1L4,GLE1,ZC3H3,FTSJ3,ZNF189,HP1BP3,NOL12,FYTTD1,STAU1,NASP,DDX24,RBX1,PRKDC,TLK1,RPS10,ZNF574,GTPBP4,SREK1,MCM2,RPSA,DHX57,DOT1L,NSA2,PAF1,UPF1,LIMK1,RBMS1,RRS1,RBBP4,CDK2,ARRB2,CD81,TERF1,ZC3HAV1,DDB1 |
| 4.145e-09 | -19.30 | Rrbp1 (ribosome binding protein 1) | protein interactions | 81910 | 218 | 70 | 17029 | 2761 |
DDX47,NUP188,NOP2,YTHDC2,YTHDF3,EBNA1BP2,KIF2C,SND1,BRIX1,MEAF6,RPL11,RPL23A,PA2G4,FBXL6,NVL,SEH1L,SRP72,RPL35,RFC3,CYP20A1,RPL38,RIOX2,RPS9,RPSA,BTBD1,DHX57,UBTF,NIP7,RPS27A,RPS14,TBL3,FAU,ZNF598,RPS15,TMUB1,RPS2,RPL15,NKRF,TOP2B,HDGFL2,HMG20A,CNOT3,PNO1,LYAR,EXOSC7,EIF2S2,RPL17,RTCB,DDX31,RBM3,AFF1,RPL19,GEMIN4,FBL,EEF1D,DDX24,FOCAD,DHX29,ZNF512,GTPBP4,ILF3,RPL8,RPL6,RPS24,USP10,LRRC1,MPG,ABCF1,RPL36,RPL32 |
| 4.168e-09 | -19.30 | KAECH_DAY8_EFF_VS_MEMORY_CD8_TCELL_UP | MSigDB lists | KAECH_DAY8_EFF_VS_MEMORY_CD8_TCELL_UP | 183 | 59 | 17377 | 2626 |
PPIB,NDUFV2,SMAP1,TXN,GNPDA1,DAP,RRM1,RACGAP1,KIF2C,LACTB2,AP3S1,STMN1,TCF19,TMEM165,REEP5,REPS1,CDKN2C,CCNA2,VMP1,PRC1,GTSE1,KIF22,TMED2,TACC3,ACSL5,BAK1,PRIM2,IDH3A,MRPL43,MKI67,RRM2,NUSAP1,CDC6,BRCA1,KRTCAP2,CCNF,ZFAND5,KIF11,ASF1B,PRDX1,CHAF1A,IDE,BIRC5,TWSG1,TAB2,PSMD8,CORO1C,MRPL27,DBI,ARNTL,CDCA5,HMGB2,KPNA2,BTF3,CDK2,RNF14,CCNB2,ATP6V0E1,VPS29 |
| 4.204e-09 | -19.29 | GNF2_CKS2 | MSigDB lists | GNF2_CKS2 | 49 | 25 | 17377 | 2626 |
GINS1,CCT2,RFC3,HNRNPAB,FOXM1,ASPM,PTTG1,CENPF,CDCA3,RRM1,SLBP,RACGAP1,NUSAP1,SMC2,MCM2,SHCBP1,FANCI,DTL,CCNA2,PCNA,BIRC5,PRC1,HMGB2,CCNB2,SMC4 |
| 4.204e-09 | -19.29 | MORF_GMPS | MSigDB lists | MORF_GMPS | 49 | 25 | 17377 | 2626 |
NDUFV2,H2AFZ,SCAMP3,CHERP,NSDHL,VDAC2,TUFM,CYCS,VDAC1,RFC2,TRIM28,PARK7,CCT8,SNRPA,NUP205,HDDC2,RAD23A,SF3B2,SDHB,NDUFV1,SMC3,PPM1G,PTPN11,NDUFS8,PTGES3 |
| 4.215e-09 | -19.28 | PLK1 (polo like kinase 1) | protein interactions | 5347 | 266 | 81 | 17029 | 2761 |
FGFR1OP,CYLD,TSC2,IVNS1ABP,MAGED1,CHD1L,KIF2C,BCL2L1,CNTROB,CCNB1,APP,ANKRD28,PHC2,MDM2,PSMA6,PIN1,DNM2,MAVS,TP53BP2,DCTN1,CDC5L,CIRBP,PSMB7,RRM2,TOPORS,MIER2,NFATC2,BRCA1,PKMYT1,BICD2,MCM2,CENPU,DDX17,HSPA4,MRPL55,CEP55,CLU,CHEK2,TUBB,ZC3HC1,HDAC2,KRBA1,CLSPN,KLHL21,GORASP1,MECP2,FAM53C,BABAM1,DNAAF5,KIF23,FOXO3,DNAJB9,SPAG5,FBXO5,CEP104,SMC3,PTEN,CENPJ,AHSA1,TANK,PRC1,ORC3,NUDC,ASPM,CIC,NEK7,PSMA1,KRAS,BORA,PSMB3,MTMR3,TSC1,PCM1,ODF2,MAPK6,CDCA5,DCAF11,USP20,PITPNA,PPP6R2,CFAP20 |
| 4.255e-09 | -19.28 | GO_CHROMATIN_ORGANIZATION | MSigDB lists | GO_CHROMATIN_ORGANIZATION | 616 | 147 | 17377 | 2626 |
H2AFZ,KDM4A,UBN1,CXXC1,SIRT2,TAF6L,CCNB1,TET3,NOC2L,TAF5L,SMARCE1,DNMT1,ARID4A,CARM1,USP34,RYBP,BAZ2A,TLK1,EHMT1,WDR82,AURKB,UTP3,PBRM1,USP22,MCM2,USP21,ASF1B,CHAF1A,DOT1L,PAF1,BRMS1,BRD2,CHD3,OGT,BAZ1B,ACTB,NAA60,HDAC2,HJURP,MUM1,PRKAA1,CTCF,EZH1,SUPT7L,TTF1,ARID1B,CDC73,RB1,HDAC7,MBD2,ZNF335,CTR9,TNRC18,HP1BP3,TSPYL4,MTA2,ZMYND11,LDB1,RTF1,ARID1A,KDM3A,DAPK3,MBIP,NAP1L1,SETD3,PRMT7,CABIN1,RUVBL2,RBBP4,CDK2,CDKN2A,SMARCD1,MBD1,ASH1L,ATXN3,DNMT3A,ARID2,SUZ12,UBR2,CHD1L,SMARCA4,CHD1,MEAF6,OIP5,SAP130,BRPF3,KDM2A,MTA1,TOP1MT,ATF2,SAP30L,SAP30,KDM3B,BRD4,KAT7,ELP4,KDM1B,MBD3,H2AFV,TRIM28,SUPT16H,RBL1,SAFB,H2AFX,ANP32E,NCOA1,BEND3,PPP5C,H3F3A,BRD9,EYA2,CBX4,DNAJC2,MECP2,EYA1,SHPRH,BABAM1,HMGN3,JMJD6,WDR5,HMG20A,IRF4,SUV39H2,HUWE1,PRDM4,NAA50,H2AFY,SS18L1,CENPM,NAP1L4,FBL,NCOA2,NASP,KAT2A,HMGN5,RCOR1,PRMT2,PCGF1,MEN1,CBX3,ATAD2,L3MBTL3,HMGB2,TAF12,CENPT,IPO4,DDB1 |
| 4.320e-09 | -19.26 | GSE24574_BCL6_HIGH_VS_LOW_TFH_CD4_TCELL_DN | MSigDB lists | GSE24574_BCL6_HIGH_VS_LOW_TFH_CD4_TCELL_DN | 192 | 61 | 17377 | 2626 |
MIF,TMEM106C,GCLM,TRIP10,CDT1,TPX2,SLC29A1,KIF2C,ORC1,FKBP2,CCNB1,PMVK,MYL6B,MFSD10,FANCI,BCAT2,EBP,KIFC1,OIP5,PSMD1,PSMA6,MCM5,TXLNA,MRPS27,ANXA5,AHCYL1,PDIA6,DNMT1,NIPSNAP1,GINS1,RFC3,NRAS,HMGN4,MAPKAPK3,CPOX,MKI67,LDHA,WDHD1,CDC6,GALK2,AURKB,NUTF2,TOMM40,SLC25A5,SNRPA,PRDX1,MAT2A,FADD,CHAF1A,PRIM1,HMGN2,SEC23IP,LTBP4,STT3A,CCDC6,DBI,COX8A,H2AFX,LTA4H,AP2S1,SSRP1 |
| 4.320e-09 | -19.26 | GSE24634_TREG_VS_TCONV_POST_DAY10_IL4_CONVERSION_UP | MSigDB lists | GSE24634_TREG_VS_TCONV_POST_DAY10_IL4_CONVERSION_UP | 192 | 61 | 17377 | 2626 |
FAM129A,TPX2,SLC25A12,SMC6,RACGAP1,NIT2,KIF2C,LANCL1,BLM,CCNB1,NCAPG,PCBP1,RMI1,HLA-A,CFLAR,CAPN2,FANCL,PA2G4,EIF2S2,SLC1A4,SEC24C,FUT8,POP7,PRC1,PPCDC,NUP107,BCL2,KIF22,KNTC1,SMC4,RFC3,MLEC,TK1,BIRC3,TACC1,ASPM,CUL3,JTB,GTPBP4,NUSAP1,SMC2,MCM2,CBFB,KIF11,FKBP3,RBM38,OPTN,TAF2,SLCO4A1,KIF18A,ATAD2,KIF18B,HINT1,HMGB2,PIEZO1,RBPJ,CCNB2,ESPL1,IFI16,PDCD4,TUBB |
| 4.320e-09 | -19.26 | GSE360_L_DONOVANI_VS_B_MALAYI_HIGH_DOSE_DC_DN | MSigDB lists | GSE360_L_DONOVANI_VS_B_MALAYI_HIGH_DOSE_DC_DN | 192 | 61 | 17377 | 2626 |
TSC2,RPS6KA1,HLA-E,UBXN1,TMX4,TKT,SLC25A12,MEF2A,CPNE3,CNOT3,VAV1,TET3,FARSA,GART,ASAP2,NDUFV1,PCNA,SMC3,NUP210,SHC1,SLC38A10,MDFIC,PPP6R1,CGGBP1,AMPD2,TXNL1,DDX28,ERCC1,NASP,SEPT9,KAT2A,SNX2,TACC1,BTG2,DCAF8,DRAP1,MRS2,RPS10,TUFM,SREK1,CDC6,PDE3B,VEZF1,GOLGA8A,PSMD8,PSMD3,FASTK,RPS14,RBMX,MEGF9,WIPI2,PREPL,MAP3K5,ZMIZ1,USF2,HEXA,FAM208A,PTDSS1,COIL,PFKP,TMEM131 |
| 4.320e-09 | -19.26 | GSE33162_UNTREATED_VS_4H_LPS_STIM_HDAC3_KO_MACROPHAGE_DN | MSigDB lists | GSE33162_UNTREATED_VS_4H_LPS_STIM_HDAC3_KO_MACROPHAGE_DN | 192 | 61 | 17377 | 2626 |
SMAP1,HJURP,MRPL42,TMBIM4,CENPF,TPX2,GLUD1,GTF3A,SDF2L1,TMED3,LACTB2,SLC35B1,C2orf49,AP3S1,TCF19,TUBGCP2,EBP,PAPOLA,RFWD3,RPA2,RPN1,ARPC5,GOT2,DUT,FUT8,PELO,ARL6IP1,CAPZA1,SEPT11,RPN2,SLC38A10,AHCY,ACSL5,PLK1,PRIM2,TSPAN31,NUDT4,RAD51AP1,IDH3A,NQO2,PBK,VDAC2,MKI67,NUSAP1,AURKB,SMC2,MCM2,EDEM2,KIF11,SNRPA,PRDX1,SRSF1,GLOD4,MTHFD2,IDE,UBXN2B,ITGB1,FKBP5,ANP32E,SPCS3,STARD3NL |
| 4.350e-09 | -19.25 | GO_DNA_INTEGRITY_CHECKPOINT | MSigDB lists | GO_DNA_INTEGRITY_CHECKPOINT | 136 | 48 | 17377 | 2626 |
CLSPN,CDT1,BABAM1,TOP2B,BLM,CCNB1,MAPK14,FANCI,CNOT3,DTL,RFWD3,RPA2,MDM2,PCNA,CCNA2,NEK6,INTS7,CENPJ,PTPN11,MSH2,GTSE1,CDKN1B,CEP63,CNOT6L,ATF2,CARM1,CDC5L,PRPF19,PLK3,PLK1,BTG2,PRKDC,TAOK1,CDC6,BRCA1,SOX4,RBM38,RPS27A,E2F4,TFDP1,PML,H2AFX,E2F1,CNOT6,CHEK2,TFDP2,ZNF830,CDK2 |
| 4.376e-09 | -19.25 | endomembrane system | cellular component | GO:0012505 | 4409 | 774 | 18223 | 2701 |
CCDC93,TMED7,RAB14,TSC2,PIGQ,HEXB,AGPAT1,TGOLN2,SYNRG,CMTM6,PSMD1,RABGAP1L,AP1M1,DNM2,NUP153,RNF26,LRRC59,RHBDD2,MGAT5,SENP1,KCNAB2,BAK1,PLK3,PGAP2,RHOBTB3,TMEM115,NRAS,AATF,PPFIA3,NUTF2,ICMT,RAB22A,SLC50A1,ARF4,PLEKHF2,RPS27A,LIMK1,MYO18A,VIPAS39,ST3GAL2,ATP6V0C,SMAD1,CHPF2,AAAS,ANXA11,NXT2,CLSPN,GGA1,SEC61G,CCZ1,RAB23,KCTD17,TMED3,APH1B,LMNA,COPB2,DDRGK1,TMEM179B,GNS,CD59,RNFT1,RTCB,TNPO3,MYDGF,MVP,NUP85,PPP6R1,NAGPA,CYFIP1,RB1CC1,PGS1,ERO1A,MAN1B1,GTPBP4,ITM2A,USP10,SSR2,ABCF1,MATR3,RHOB,CYB5A,RDH11,MAGED2,SCARB2,OSBPL11,KPNA1,TXNDC16,RUFY3,HEXA,RNF139,SNX14,NUP58,ALS2,RHOG,EXOC3,ANKRD27,ABCA3,ANK3,VTI1A,MON1B,TMEM97,TBC1D13,RXYLT1,NIPA2,NIT2,SLC35B2,PRKACA,LCLAT1,STAM,CPNE3,REPS1,KTN1,APP,RAB21,AHCTF1,ATP2A2,UTP18,TBC1D22A,MTA1,TBC1D14,NUP107,CLCN6,NSFL1C,ANKRD13C,RBM15,CLN6,GCC1,TMEM9,DCTN1,SNX8,ENPP4,CPNE1,SEC61B,ERMP1,GOPC,ATP6V0A1,HTATIP2,GORAB,DNAJA1,TMEM147,RAB1A,ALDH3B1,PEX5,SEC61A1,VPS26B,CAMKMT,WDR7,MBOAT1,TICAM1,PDXK,TUBB,TMBIM4,ANXA6,FLOT1,TRAK1,GMCL1,IFT27,WRB,CAPN2,GOLM1,PSMD2,PDCD10,NDUFB4,HUWE1,ARF5,ST8SIA2,TPCN1,S100A6,TMX1,LYPLA2,SPTAN1,MOB4,STAU1,HEBP2,PDE3B,PICALM,KEAP1,MAGT1,WNT5B,DBI,FAM3C,LRPPRC,PML,AEN,PSAP,FAF1,SNAPIN,AGRN,PPP1R15B,YTHDC2,NENF,CDIPT,SEC16A,RUFY1,KCMF1,SSR1,PRNP,FANCL,RAB8A,NUP210,INTS1,ZFYVE27,APH1A,CYSTM1,PSMG1,EZR,LRP5,ESYT1,KRTCAP2,STX16,RAB5B,LSG1,RHEB,OPTN,NECAP2,DPYSL3,ALG3,TRAM2,TBC1D17,AGPAT2,GRIPAP1,NRM,KPNA2,PIEZO1,CLN3,NAA60,NUMB,LZTR1,TMUB1,NEMP2,DNAJB2,CENPF,NKD2,LAMTOR3,SDC2,ASAH1,RACGAP1,CDK13,RAB6A,B4GALT4,C1GALT1,MLX,NUS1,VMP1,PPIL2,ARL6IP1,SLC27A4,GLE1,PREB,CYTH1,ABHD2,TRAPPC9,NSDHL,ACSL3,UTP15,ARMC8,APPL1,NPIPA1,ZDHHC3,NMT2,RMC1,MOSPD3,GOLGA4,GALNT2,PCM1,SYNCRIP,ORMDL2,TMEM168,SNAP23,LAMTOR4,ZDHHC7,SIL1,ECPAS,UNC13C,NIPA1,SART1,GLT8D1,DYNLL1,TOR1AIP1,SLC2A1,TMX4,COPE,ZFYVE21,RRAGC,ATP6V1B2,LYN,BCAP31,SEC11A,CSDE1,ATP6V0B,WDR44,BCAP29,CORO1A,MINPP1,LMAN1,AHCYL1,GM2A,SNX25,CLCN3,TIMP2,PPT1,RAB7A,PPIE,SLC26A6,MTMR6,NUP155,DCLRE1C,CHMP2B,TXNL4A,RHBDF2,TMEM201,DNAJC10,ATP1A1,SCAP,CLK3,UBXN2B,PSMD3,AP1S1,CHMP4B,LTA4H,AP2S1,CHID1,ZC3HC1,PARD3,INTS2,SLC30A9,GOLIM4,PDAP1,TMX3,ARFIP2,SUMF1,ARF1,GGA2,AP3S1,SCYL2,DNAJB9,TFRC,PTPN2,CTSS,SLC35B4,DDX31,CAMK2G,RNF5,MLEC,RHOA,SNX2,RANGAP1,PNPLA8,NEU1,RAB18,SEC23IP,KPNA4,PDCD6,ATP6V1D,GOLGA7,SNAP29,GLG1,PGRMC1,IMPDH1,PKD2,SPCS3,PGAM1,CHMP7,RPS6KC1,NUP188,PDCD6IP,TMEM203,PRKCSH,ADAM10,ZDHHC8,TMEM109,AP3M2,TAP1,GYG1,NHLRC3,UBE2I,IKBIP,PARK7,RIC1,KIFC1,PA2G4,SNUPN,ASAP2,DBNDD1,CYB5RL,RAB4A,CNPY4,AP2B1,TRA2B,CISD2,MARCH2,SPTSSA,TFG,SEH1L,SRP72,SGCE,USO1,ATG9A,AKT2,ARHGAP45,GALNT7,SLC17A5,MCFD2,RAB2B,STT3A,TMED10,ITGB1,SARAF,RRS1,ARRB2,RTN3,B4GALT2,SVIP,PPIB,MAPRE1,DNAJC5,SCOC,GMFG,HLA-E,RRM1,ACAP1,B4GALT1,MAN2B1,SLC35B1,NOTCH2,PMF1,PSEN1,TMEM165,VPS25,PDXDC1,COPG2,NPLOC4,WDR48,FKBP1A,SLC31A1,RNF121,RPN1,ARPC5,SNX18,LRRC8D,ZNRF2,DAD1,PIGG,TPST1,ATP6V0A2,OSTF1,PCYT2,PIKFYVE,TNRC18,LPCAT1,SYTL3,EEF1D,APOL1,TMED2,FDFT1,EIF5A,FTL,GCC2,PIGT,CPQ,SIGMAR1,RDH10,USF3,MFNG,C1orf35,GORASP2,ADRB2,PKM,GOSR1,CCT8,MAP2K2,XRCC5,PI4K2A,DERL1,SEC31A,CAT,GOLGA2,NSF,ERGIC3,ACLY,ARAP1,LPCAT4,APPL2,USP32,VCPIP1,SAMD8,SMPD4,GPI,MAP3K5,PPP6R3,CDK2,NRBP1,NDC1,CYTIP,ATXN3,SYS1,TRIP10,RAB11B,RAF1,CAST,RAC1,GPR89A,SLC39A13,OLA1,POMP,ADPGK,BCL2L1,AP1B1,CD320,TERF2IP,CRKL,APLP2,SIAH1,MTMR4,LPIN2,TNPO2,CDKN1B,BRI3,TAP2,TMBIM1,ANKLE2,CCT2,ATP13A1,CUL3,VDAC2,PKMYT1,AP4E1,SERP1,ERC1,CHMP4A,DSN1,DDOST,JAK1,CERS6,RAB24,GOLGA8A,SEL1L,NCLN,ATF6,B4GALT3,DYNC1LI2,CSNK1D,RHEBL1,ANKRD13D,B4GALT5,MANBA,BRAP,AGPAT3,SDF2L1,RAB11A,POFUT1,REEP5,HEATR5B,HLA-A,PIP5K1C,EBP,TMCC3,CRAT,AHSA1,FUT8,SLC38A10,CNN2,OSTC,CNPY3,PACS2,MSH6,DENND4C,PACS1,KCNQ1,ARSK,RPL27A,MACF1,SPPL2B,SH3GLB1,CBX3,YIF1A,NUCB1,TMEM127,PLD3,HGS,PRDX3,STX18,ASNA1,WDR91,GPR89B,IPO4,VPS29,ESYT2,MIB2,ADA2,PIGM,COPA,MOGS,ALKBH5,PTP4A3,AGFG1,FKBP2,MAP1LC3B,BECN1,MAPK14,MRPL19,RNF103,PCYOX1L,DST,RAP1A,CDC42,THADA,AP3S2,RAB35,IMPAD1,PHTF1,SRI,HADHB,RP2,TECR,SLC35C2,CARMIL1,DRAM2,LARS,DPM1,NCK1,LAP3,VHL,LRBA,SUMF2,PITPNB,MAN2A2,MIA2,CRCP,CAB39,CHEK2,CLU,VPS4A,ROCK1,GALNT10,CHPT1,RPS26,ATP6V0E1,CAPN1,STARD3NL,UBE2D3,TBC1D12,PIGN,AGTRAP,TM9SF4,GORASP1,UBXN1,CDIP1,CIB1,EPN1,PCSK7,XPO7,QSOX2,RHBDD1,NUP205,DTL,PYURF,BANF1,EI24,KIFAP3,BCL2,YBX1,ATP6V0D1,KDELR1,VOPP1,CREG1,ERLIN1,RPL6,SYVN1,VKORC1,CAND1,NSMF,SIAH2,NUP62,CTSA,EHD4,TMEM14A,PTDSS1,APOL2,TMEM106C,WASF2,SNX27,CHMP2A,CORO7,ASH1L,GNPNAT1,CHERP,CLCC1,EXT2,ANKRD28,ANKLE1,UBXN2A,SAR1A,AKAP8,PPP6C,RPN2,CYB5R1,APOOL,CLTB,PDIA6,F2R,ABI1,SCYL3,HTRA2,EBAG9,CHP1,MOSPD1,ACSL5,UBQLN4,NXT1,FAM172A,PSMB7,TOR1AIP2,BICD2,ERBIN,EDEM2,TOLLIP,PEF1,SURF4,VPS26C,TAB2,HNRNPR,STAT6,CANT1,REEP4,MAPK1,ABCA1,TMEM33,MIF,DNAJC2,CDS2,GOLPH3L,RAE1,TOR3A,SCYL1,SRGN,NUP54,VPS45,CHIC2,XPR1,MAN1A1,SPPL2A,FERMT3,FGFR3,KLHL20,SEC24C,RRBP1,DUS2,ZDHHC13,ANP32A,ARHGEF2,ATG13,YIF1B,SLC35A1,MYO5A,TGFB1,B3GALT6,ELOVL5,ZDHHC18,FAM49B,ATP2C1,COG1,RFFL,WDR81,MEN1,MAPK3,HSPA1B,LEMD2,CTSL,HLA-B,OSBPL8,PLOD3,PREPL,HRAS |
| 4.404e-09 | -19.24 | HDGF (heparin binding growth factor) | protein interactions | 3068 | 214 | 69 | 17029 | 2761 |
DDX47,NOP2,OLA1,EBNA1BP2,BRIX1,MAPK14,APP,SSR1,HNRNPA2B1,MRPS27,LRRC59,ASB6,CDC5L,SRP72,EXOSC6,RPL35,RFC3,INTS13,DNAJA1,SLC25A5,DHX15,SRSF1,SUPT16H,DDX17,KIF2A,MAP4,BAZ1B,KPNA2,SMAD4,HDAC2,SSRP1,EWSR1,NACA,DHX9,WDR5,MCTS1,LYAR,SUB1,SMC3,EIF2S2,RPL17,EFTUD2,H2AFY,AHCY,RPL19,FBL,MSH6,HP1BP3,NUDC,STAU1,HMGN1,KAT2A,PRKDC,BMS1,SRSF5,MPG,ABCF1,PHF6,CBX3,XRCC5,RPA1,RPL32,RBMX,ZRANB2,DDX5,SRSF3,RBBP4,C7orf26,ZC3HAV1 |
| 4.436e-09 | -19.23 | regulation of macroautophagy | biological process | GO:0016241 | 165 | 55 | 17256 | 2622 |
TBC1D12,PRKAB1,FEZ2,TSC2,SCOC,PHF23,PRKAA1,LAMTOR3,RRAGC,UBQLN2,ATP6V1B2,PRKACA,BECN1,PIP4K2A,EPM2A,CDK5,ATP6V0B,TIGAR,RALB,TBC1D14,ATP6V0A2,ATG13,PIKFYVE,LRSAM1,ATP6V0D1,HTRA2,RNF5,MLST8,ATP6V1G1,CDC37,UBQLN4,RB1CC1,PIP4K2C,GBA,ATP6V0A1,ADRB2,SH3GLB1,USP36,RHEB,OPTN,MAPK3,MFN2,MTMR3,TSC1,ATP6V1D,CHMP4A,VPS26B,LAMTOR4,EXOC4,CHMP4B,ATP6V0C,ATP6V1C1,SMURF1,ATP6V0E1,CAPN1 |
| 4.465e-09 | -19.23 | GO_SIGNAL_TRANSDUCTION_IN_RESPONSE_TO_DNA_DAMAGE | MSigDB lists | GO_SIGNAL_TRANSDUCTION_IN_RESPONSE_TO_DNA_DAMAGE | 92 | 37 | 17377 | 2626 |
MIF,FOXM1,CCNB1,MAPK14,FOXO3,MAD2L2,CNOT3,TFAP4,MDM2,PCNA,SP100,CENPJ,CDKN1B,GTSE1,CEP63,CNOT6L,CARM1,PRPF19,CDC5L,PGAP2,PLK3,PRKDC,BTG2,USP10,BRCA1,SOX4,RBM38,RPS27A,E2F4,HIPK2,TFDP1,E2F1,PML,CNOT6,CHEK2,TFDP2,CDK2 |
| 4.465e-09 | -19.23 | MORF_RAB5A | MSigDB lists | MORF_RAB5A | 92 | 37 | 17377 | 2626 |
RAE1,RAC1,ENSA,COX4I1,UBE4A,BCAP31,COPB2,MBD4,ARF5,RAD23B,BUD31,PPP6C,EIF5,ATP6V0D1,TMED2,SLC25A1,EBAG9,DPM1,GMFB,WBP2,CHMP2B,OGFR,RAB1A,STX16,PICALM,MAPK3,PDCD6,TMED10,COX7A2L,COX5A,DUSP11,CLN3,MYL12B,COIL,PSMC1,FUBP1,RNF114 |
| 4.492e-09 | -19.22 | MOOTHA_HUMAN_MITODB_6_2002 | MSigDB lists | MOOTHA_HUMAN_MITODB_6_2002 | 401 | 105 | 17377 | 2626 |
NDUFA5,COX15,IMMT,TOMM20,TXN,NDUFB6,RPLP2,SUCLG1,IVNS1ABP,MRPS15,MRPL39,MDH2,RAF1,MCCC1,GLUD1,BCL2L1,OAT,SDHA,MRPL19,SLC25A37,BCAT2,FARSA,DECR1,NRF1,GOT2,TIMM23,DUT,MRPL34,CS,HADHB,MRPS27,OGG1,GPX4,ACSL5,BAK1,PPIF,IDH3A,CPOX,MRPL12,VDAC2,NDUFA7,OGDH,NDUFB1,POLG2,SLC25A5,MBD3,ODC1,MRPS14,PDHX,MRPL2,DAP3,TIMM13,TONSL,TIMM17A,MLYCD,COX5A,UQCRH,CLN3,MRPL13,COX5B,NDUFV2,NDUFS1,MRPL9,MRPL42,MUT,MRPS2,SLC25A12,NDUFA4,COX4I1,CYCS,NDUFS7,NDUFS4,NDUFA2,NDUFB4,CRAT,BDH1,BCL2,NDUFS8,MRPL48,CYC1,MRPL11,ACAD8,ALDH18A1,NDUFA3,LYPLA2,SLC25A1,TIMM8B,TK1,ABCF2,ACSL3,TUFM,MRPS10,MRPL16,TOMM40,CYB5A,MFN2,AKAP1,SDHB,MTHFD2,PRDX3,COX7A2L,COX8A,ACAT1,ACADM,IDH3B |
| 4.568e-09 | -19.20 | GSE17974_CTRL_VS_ACT_IL4_AND_ANTI_IL12_24H_CD4_TCELL_DN | MSigDB lists | GSE17974_CTRL_VS_ACT_IL4_AND_ANTI_IL12_24H_CD4_TCELL_DN | 179 | 58 | 17377 | 2626 |
TMEM106C,WSB2,INTS2,POLA2,CKLF,TPX2,SDF2L1,SND1,SLC25A43,RMI1,VPS25,MCTS1,FLAD1,CDK5,SNRNP25,CCNA2,SUV39H2,GOT2,CENPJ,MCM5,MEA1,CENPM,RNASEH2A,SGCB,FTSJ3,IMPA2,TIMM50,SAP30,RPP25,TDP1,TK1,ASPM,RAD51AP1,TMEM126B,MRPL12,SCFD2,CCDC34,WDHD1,PSMG1,MTX1,GAR1,RFC2,PRDX1,FADD,PRIM1,STOML2,PAF1,SLC19A1,BIRC5,MFAP1,PSMD8,ZNF367,ACOX1,ACAT1,MLYCD,RUVBL2,SNRPG,TMEM14A |
| 4.568e-09 | -19.20 | GSE14415_INDUCED_TREG_VS_FAILED_INDUCED_TREG_UP | MSigDB lists | GSE14415_INDUCED_TREG_VS_FAILED_INDUCED_TREG_UP | 179 | 58 | 17377 | 2626 |
MCM10,MRPL42,NF1,URB2,UCK2,CDCA3,NANS,FAM136A,FKBP2,TUBGCP2,PARK7,PNO1,FBXO5,CALM2,LYAR,IRF4,ERH,IARS,AHSA1,DUT,BANF1,MECR,CS,GEMIN6,FBL,CLTB,PPA1,IMPA2,EEF1D,GINS1,TK1,RFC3,POLR2L,PRIM2,LAP3,PBK,PPIE,CYP20A1,LDHA,RNPS1,RRM2,AURKB,ZDHHC3,ASF1B,PRDX1,PSMC4,HMGN2,PRIM1,GEMIN5,RAD18,TMED10,BIRC5,TIMM17A,PRMT7,TAF12,CCNB2,FAM72A,POLQ |
| 4.568e-09 | -19.20 | GSE17721_CTRL_VS_POLYIC_8H_BMDC_UP | MSigDB lists | GSE17721_CTRL_VS_POLYIC_8H_BMDC_UP | 179 | 58 | 17377 | 2626 |
NCOR2,GCLM,GNPNAT1,MRPS2,UBXN1,SNX15,CUTA,TIA1,HAUS4,SEC16A,PIP4K2A,BCAP31,PNO1,CDK5,CCNA2,AKAP8,BCAP29,TARDBP,TECR,MED22,RNF5,MAP4K4,TMEM216,DNAJC9,ARHGDIB,DIDO1,ADRB2,VDAC1,ANLN,ARPC1A,ODC1,CCT8,DHX15,CLNS1A,ASF1B,RXRB,NUCB1,ORMDL2,DHX16,LIMK1,PRPS2,OAZ2,NFIL3,NDUFA11,RPLP1,FTSJ1,QRSL1,ACAT1,MDH1,CTSA,GAS2,TMEM101,PDXK,FAU,CD81,YWHAH,MRPL3,IPO4 |
| 4.628e-09 | -19.19 | V$ELK1_02 | MSigDB lists | V$ELK1_02 | 233 | 70 | 17377 | 2626 |
IMMT,TRAF7,CHERP,NF1,RAB11B,DNAJC24,BCL2L1,POMP,AP1B1,FBXO22,SHC1,PPME1,AP1M1,OGG1,MTPN,CGGBP1,NRAS,KAT7,SNRPB,PPIE,KRTCAP2,ARL5B,STOML2,NECAP2,RPL37,TBC1D17,DDOST,UQCRH,ZBTB11,MRPL13,PSMC1,AP2S1,CHID1,NDUFS1,EPN1,CDK13,AKT1S1,MYL6B,HMG20A,PRPF18,FERMT3,FBXO3,GART,CCP110,MED8,VMP1,SEC24C,PPIG,MEA1,RPL19,MTX2,LYPLA2,EIF5A,TTPAL,TIMM8B,ACP2,TSTA3,BTAF1,TUFM,LLPH,SYVN1,TOMM40,PALB2,COX8A,USP32,SAMD8,DDX5,NAA20,MRPL3,IPO4 |
| 4.681e-09 | -19.18 | protein deubiquitination | biological process | GO:0016579 | 283 | 81 | 17256 | 2622 |
USP7,TOMM20,CYLD,ATXN3,USP39,INO80E,USP48,BECN1,STAM,BIRC2,USP5,RAD23A,CCNA2,PSMA6,PSMD1,BABAM2,MDM2,ABRAXAS2,UCHL5,RAD23B,JOSD1,MAVS,USP34,BIRC3,PSMA8,PSMB7,USP22,BRCA1,KDM1B,PSMB9,USP21,USP36,SMAD2,RPS27A,PSMD8,PSMD3,AXIN1,OGT,ACTB,DMWD,SMAD1,USP11,ARRB2,PSMC1,USP53,SMAD4,USP13,DDX58,OTUD5,CLSPN,BABAM1,ASXL2,PSMD9,WDR48,PSMD2,CCP110,PTEN,AXIN2,RNF135,ZRANB1,RHOA,KAT2A,FOXK1,TNFAIP3,USP42,USP10,PSMA1,ADRB2,OTUD3,RHOT1,PSMB3,PSMC4,HGS,KEAP1,EPOP,USP32,SIAH2,VCPIP1,USP20,MBD6,YY1 |
| 4.707e-09 | -19.17 | GO_REGULATION_OF_LIGASE_ACTIVITY | MSigDB lists | GO_REGULATION_OF_LIGASE_ACTIVITY | 128 | 46 | 17377 | 2626 |
GCLM,GORASP1,CUL1,CCNB1,DCUN1D4,PSEN1,PSMD9,PARK7,MAD2L2,FBXO5,PSMD2,PSMD1,PSMA6,PTEN,PIN1,ANAPC7,PLK1,PSMA8,PSMB7,PSMA1,ANAPC2,TOPORS,DCUN1D5,CDC23,RAB1A,PSMB9,PSMB3,PSMC4,MASTL,CDC16,MID1IP1,CDC27,GOLGA2,RPS27A,PSMD8,AXIN1,PSMD3,LIMK1,XRCC3,CDK2,GEN1,XRCC4,UBE2C,PSMC1,ANAPC4,CDKN2A |
| 4.709e-09 | -19.17 | GCM_NF2 | MSigDB lists | GCM_NF2 | 275 | 79 | 17377 | 2626 |
RAB14,GLT8D1,ASH1L,DDX47,TRAF7,SNX15,ALKBH5,KLHL18,TM9SF3,BCL2L1,SLC35B2,ZNF275,ABHD16A,ZER1,SAP130,NAPG,MTMR4,IMPAD1,TBC1D14,CS,TNPO2,CHTOP,ASB6,MTPN,KDM3B,UBQLN4,SNRNP200,ZNF559,EXOSC6,BAZ2A,WBP2,SUMF2,PRKRA,ZFAND5,MBD3,H2AFV,DDX17,ANKRD10,HNRNPR,VPS26B,SAFB,U2SURP,NCLN,COPS6,BRD9,AAAS,B4GALT2,WSB2,GORASP1,MRI1,STRN4,ATG2B,FOXO3,GFM2,FAM192A,PPIG,PRDM4,TTC17,ZNF710,PACS2,LUC7L2,SAMD4B,MOB4,PHF10,ZNF84,TSPYL4,ZNF512,RABIF,FBXO9,PATL1,ZFR,CAND1,MFN2,HGS,GOLGA7,SLC38A7,FN3KRP,MYO9A,RPS6KC1 |
| 4.710e-09 | -19.17 | EFTUD2 (elongation factor Tu GTP binding domain containing 2) | protein interactions | 9343 | 160 | 56 | 17029 | 2761 |
SART1,C9orf78,CDC40,CYLD,XAB2,SUZ12,SF3B1,DHX9,USP39,SNRPD3,LMNA,RPA2,GOLM1,GSTK1,MDM2,EIF4A3,HUWE1,PIN1,AHSA1,ZNF746,EFTUD2,RPAP1,CRY2,ECD,HNRNPM,CDC5L,PRPF19,RPAP3,CYFIP1,SNRNP200,HARS,PRKDC,SNRPB,ZMYND11,SF3B6,SMU1,RNPS1,CUL3,CRNKL1,SREK1,LSM8,RANGAP1,BRCA1,SF3A2,SRSF1,RPA1,DDX23,DDX17,DUS3L,HNRNPR,SH3GLB2,PRPF4,SNRPG,RUVBL2,ARRB2,PRPF4B |
| 4.763e-09 | -19.16 | GSE24574_NAIVE_VS_TCONV_CD4_TCELL_DN | MSigDB lists | GSE24574_NAIVE_VS_TCONV_CD4_TCELL_DN | 188 | 60 | 17377 | 2626 |
MIF,SRM,RHOG,EXOC3,MMACHC,IMMT,TXN,URB2,SRGN,ADO,NKRF,NCKAP1,DCUN1D4,OAT,HDDC2,BCAT2,CFLAR,FARSA,PA2G4,HOMER1,ZNF75D,PSMD1,PSMA6,UTP18,MTA1,MRPS27,ZNF200,PDCD2,RPN2,AHCY,GEMIN4,CPSF4,LPCAT1,COPS8,METTL1,ANKLE2,RFC3,MAPRE2,POLR2G,AATF,TSTA3,HMGN4,MAPKAPK3,PPT1,IDH3A,ABCF2,HNRNPF,NUTF2,PSMB3,FADD,CAND1,KRIT1,PPP2CA,UAP1,CCDC86,ELMO1,TIMM17A,HPS5,SEL1L,ZBTB24 |
| 4.763e-09 | -19.16 | GSE28726_ACT_CD4_TCELL_VS_ACT_NKTCELL_UP | MSigDB lists | GSE28726_ACT_CD4_TCELL_VS_ACT_NKTCELL_UP | 188 | 60 | 17377 | 2626 |
SRM,MMACHC,TXN,SCAMP3,URB2,ADO,CUL1,NKRF,SLC29A1,SNAPC4,HDDC2,CFLAR,RPA2,SUB1,HOMER1,PSMD1,MTA1,SRI,TXLNA,MRPS27,ZNF200,PDCD2,TRA2B,RPN2,GEMIN4,LPCAT1,COPS8,SP3,METTL1,RFC3,MAPRE2,MKLN1,POLR2G,AATF,TSTA3,HMGN4,MAPKAPK3,PPT1,AMD1,ACSL3,HNRNPF,LDHA,ATXN1,NUTF2,VDAC1,TXNL4A,MACF1,MBD3,CAND1,PPP2CA,CCDC86,ELMO1,TIMM17A,HPS5,DBI,TCOF1,RUVBL2,DDB1,ZBTB24,DDX42 |
| 4.763e-09 | -19.16 | GSE3982_CENT_MEMORY_CD4_TCELL_VS_TH1_DN | MSigDB lists | GSE3982_CENT_MEMORY_CD4_TCELL_VS_TH1_DN | 188 | 60 | 17377 | 2626 |
NDUFV2,PKP4,C19orf53,FOXM1,SEC61G,UFC1,PTTG1,CENPF,TMEM97,FLOT1,SDF2L1,SLC25A44,BLM,NCAPG,STMN1,MAN1A1,CD59,SNRNP25,RPN1,ATP2A2,PELO,RAD23B,PPCDC,AKR1B1,TIMELESS,JOSD1,KNTC1,RNASEH2A,UBE2M,HTRA2,MYO5A,SAP30,NASP,LAP3,SNRPB,PBK,ACSL3,MRPL12,RRM2,EXOSC9,NUP155,BRCA1,SMC2,RAD54B,YIF1A,MTHFD2,KIF18A,BIRC5,MFAP1,PSMD3,PPM1G,NFIL3,CEBPG,COX8A,CHEK2,MRPL13,CCNB2,ESPL1,TUBB,TMEM33 |
| 4.763e-09 | -19.16 | GSE22935_UNSTIM_VS_24H_MBOVIS_BCG_STIM_MYD88_KO_MACROPHAGE_UP | MSigDB lists | GSE22935_UNSTIM_VS_24H_MBOVIS_BCG_STIM_MYD88_KO_MACROPHAGE_UP | 188 | 60 | 17377 | 2626 |
CHMP2A,SYS1,TRIP10,CAST,FAM53C,B4GALT1,GGA2,MAP1LC3B,BIRC2,STAM,ANKIB1,GTF2F1,PAIP2,PDCD10,MEX3C,SLC1A4,ARPC5,DBNDD1,IL6ST,PRDM4,PPP4R1,GMEB1,SOCS6,SAP30L,ABCC1,RYBP,TTPAL,ERCC1,IFRD1,ABHD2,BIRC3,GABPA,ELL2,BTAF1,PIP4K2C,WBP2,KRAS,PNPLA8,USP22,AZI2,RAB1A,NEU1,ARF4,SOCS7,LEMD2,RAB18,PON2,KPNA4,DUSP3,MAFK,NFIL3,TBPL1,UHRF2,RWDD4,RBMS1,ATP6V0C,DVL1,FBXL3,LRP8,CWC25 |
| 4.781e-09 | -19.16 | DDX3X (DEAD-box helicase 3, X-linked) | protein interactions | 1654 | 156 | 55 | 17029 | 2761 |
RPS2,CYLD,SUZ12,DYNLL1,EIF3D,SUMO2,RAC1,CUL1,CSNK2A1,IRF3,SND1,LMNA,SAC3D1,RPA2,EIF4A3,PIN1,AHSA1,PIK3R2,ZNF746,CRY2,TARDBP,MAVS,TERF2,SRPK2,STAU1,EIF3L,VHL,ABCF2,CUL3,SREK1,SRSF5,MCM2,MBD3,RPS9,MATR3,EIF3G,EIF3A,EIF3H,RPA1,CAND1,GEMIN5,EIF3K,SYNCRIP,HNRNPR,ODF2,IMPDH1,NUP62,COPS6,YY1,CDK2,ARRB2,HNRNPDL,CD81,POT1,BYSL |
| 4.817e-09 | -19.15 | SFPQ (splicing factor proline and glutamine rich) | protein interactions | 6421 | 189 | 63 | 17029 | 2761 |
UNK,SART1,IMMT,CYLD,EWSR1,TXN,DHPS,SF3B1,RAC1,CBLL1,CSNK2A1,TOP2B,THRAP3,UBE2I,PARK7,LMNA,HNRNPA2B1,RPA2,MDM2,SMC3,NUP210,HUWE1,MCM5,PIN1,AHSA1,SRSF4,ZNF746,EFTUD2,HNRNPM,CDC5L,SP3,STAU1,PRRC2A,PSPC1,ILF3,SREK1,KRAS,TOPORS,BRCA1,DIDO1,SRSF5,TOMM40,MCM2,SLTM,TARS,SNRPA,RPA1,DDX17,SYNCRIP,HNRNPR,STAT6,ACAT1,COX5A,FUS,SRSF3,CDK2,ARRB2,MAPK1,CD81,POT1,ZC3HAV1,HDAC2,SMARCD1 |
| 4.824e-09 | -19.15 | Eif3e (eukaryotic translation initiation factor 3, subunit E) | protein interactions | 16341 | 109 | 43 | 17029 | 2761 |
RPS15,RPS2,NOP2,EIF3D,RPL15,TOP2B,EBNA1BP2,BLM,BRIX1,PNO1,RPL11,RPL23A,FBXL6,UTP18,RPL17,PPP6C,RPL19,CGGBP1,HP1BP3,PPAN,EIF3L,RPS10,RPL6,GTPBP4,RIOX2,ILF3,RPL8,RPL38,RPS24,RPL27A,EIF4G2,RFC2,EIF3G,LSG1,RPSA,EIF3A,EIF3H,SUPT16H,EIF3K,RPL32,BRWD1,RPS14,FAU |
| 4.914e-09 | -19.13 | GPROTEINBRPT | prints domains | PR00320 | 84 | 28 | 4652 | 473 |
WSB2,CORO7,COPA,TRAF7,WDR1,RAE1,POC1A,WDR18,STRN4,SMU1,WDR82,WDR5,GNB2,WDR48,COPB2,GEMIN5,WDR44,TBL3,DCAF11,FBXW2,PRPF4,TAF5L,RBBP4,STRAP,SEH1L,MLST8,PRPF19,WDR41 |
| 4.994e-09 | -19.11 | GSE2770_IL12_ACT_VS_ACT_CD4_TCELL_6H_UP | MSigDB lists | GSE2770_IL12_ACT_VS_ACT_CD4_TCELL_6H_UP | 175 | 57 | 17377 | 2626 |
NDUFS1,RRP15,MUM1,UCK2,TATDN3,UBE2Z,CSNK2A1,SMARCA4,NIT2,ARF1,KCMF1,YY1AP1,RGS1,GTF2F1,KIF5B,NDUFA2,SLC38A5,RPL17,SNX18,INTS1,BDH1,ZFYVE27,CORO1A,CYC1,ATP6V0D1,RHBDD2,TMEM14C,EBAG9,PRPF19,FYTTD1,CCDC57,TSTA3,RNASEH2C,SLC16A7,RPL8,MRPL16,PKMYT1,PRMT2,EIF4H,CYB5A,YIF1A,ZNF777,C1orf131,SURF4,MRPL55,CSK,STK38,GOLGA8A,ARAP1,COX5A,SSNA1,DMWD,VPS4A,UBE2C,NAA60,DDB1,GEMIN7 |
| 5.041e-09 | -19.11 | MORF_UNG | MSigDB lists | MORF_UNG | 70 | 31 | 17377 | 2626 |
TMEM106C,CCT2,KARS,POLR2I,H2AFZ,HNRNPAB,NSDHL,TUFM,CYCS,CDC23,VDAC1,MRPL19,TRIM28,SRSF1,RPA1,HNRNPA2B1,PCNA,PDCD6,UTP18,MFAP1,ATIC,AHSA1,BANF1,PPM1G,RAD23B,MSH2,BAZ1B,KPNA2,MRPL3,HDAC2,NUDC |
| 5.041e-09 | -19.11 | GNF2_EIF3S6 | MSigDB lists | GNF2_EIF3S6 | 116 | 43 | 17377 | 2626 |
RPS15,KARS,DDX47,RPS2,ST13,RPLP2,EIF3D,NACA,RPL15,GTF3A,RPL11,RPL23A,PAPOLA,NOL11,RPL17,RPL19,FBL,PABPC1,EIF3L,RPL29,HMGN1,RPL35,RPL8,RPL38,RPL6,RPS10,RPS24,RPL27A,RPS9,EIF3H,RPSA,RPL36,NSA2,EIF3K,RPL37,DAP3,NAP1L1,RPL32,QARS,RPS14,BTF3,FAU,CCDC59 |
| 5.064e-09 | -19.10 | GO_CATALYTIC_STEP_2_SPLICEOSOME | MSigDB lists | GO_CATALYTIC_STEP_2_SPLICEOSOME | 81 | 34 | 17377 | 2626 |
SART1,CDC40,ZCCHC8,XAB2,SF3B1,RBM8A,DHX8,SNRPD3,SF3B2,HNRNPA2B1,EIF4A3,CWC27,EFTUD2,GPATCH1,AQR,PABPC1,HNRNPM,CDC5L,PRPF19,SNRNP200,SNRPB,PPIE,HNRNPF,CRNKL1,PPWD1,SF3A2,DDX23,SRSF1,SYNCRIP,HNRNPR,RBMX,DDX5,SNRPG,PRPF4B |
| 5.076e-09 | -19.10 | GO_REGULATION_OF_MRNA_METABOLIC_PROCESS | MSigDB lists | GO_REGULATION_OF_MRNA_METABOLIC_PROCESS | 112 | 42 | 17377 | 2626 |
SRSF6,RBM8A,TIA1,JMJD6,SECISBP2,THRAP3,CCNB1,CDK11B,RBM4,CDC73,PAPOLA,HNRNPA2B1,NSRP1,SRSF4,CTR9,TRA2B,AHCYL1,CPSF4,PABPC1,SRPK2,SRSF10,PRPF19,RBM15B,YTHDC1,RBM42,POLR2G,BTG2,RNPS1,CDK11A,IWS1,PAF1,UPF1,RBM25,SYNCRIP,HNRNPR,RBMX,SAFB,DDX5,SRSF3,SNRNP70,TOB1,ZC3HAV1 |
| 5.225e-09 | -19.07 | RPL4 (ribosomal protein L4) | protein interactions | 6124 | 202 | 66 | 17029 | 2761 |
CYLD,NOP2,RPLP2,SUMO2,CUL1,SND1,BRIX1,RPL11,RPL23A,PA2G4,MDM2,EIF4A3,PIN1,TARDBP,TFG,FTSJ3,RPL29,RPL35,RPL38,RNPS1,CUL3,BRCA1,SLC25A5,MAK16,RPS9,RPSA,NIP7,RPS27A,RPS14,RPLP1,UQCRH,FUS,COPS6,RRS1,ARRB2,RPS26,NIFK,RPS15,RPS2,RPL15,ATP5F1B,HUWE1,RPL17,ZNF746,RPL19,PTGES3,FBL,MAP3K14,PABPC1,STAU1,DDX24,ZNF512,ILF3,RPL8,GTPBP4,RPL6,RPS10,RPS24,RPL27A,TARS,PHF6,CAND1,RPL36,RPL32,CD81,GPATCH4 |
| 5.243e-09 | -19.07 | GSE16450_CTRL_VS_IFNA_6H_STIM_MATURE_NEURON_CELL_LINE_DN | MSigDB lists | GSE16450_CTRL_VS_IFNA_6H_STIM_MATURE_NEURON_CELL_LINE_DN | 184 | 59 | 17377 | 2626 |
DCAF15,GPBP1L1,IVNS1ABP,SEC61G,TSC22D3,CAST,MUM1,MYH9,AKT1S1,UBE2I,CRLF3,IL21R,NPLOC4,RBM17,RAB8A,EFTUD2,XPA,RAB4A,PTGES3,CNPY3,ILKAP,S100A6,KDM3B,TSHZ1,CDKN2AIP,ORAI2,CSRP1,ERF,WDR1,BTG2,PPIE,CIRBP,NARF,PSMB7,EIF2AK1,ARID1A,ADRB2,EML4,LSG1,MARK2,GIGYF1,NSA2,SERTAD2,MID1IP1,RBM25,LSM6,SAFB,TPP2,ITGB1,COX8A,HMGB2,ATP6V0C,STK11,YWHAZ,BTF3,CCDC125,CD81,N4BP2L2,DDX52 |
| 5.243e-09 | -19.07 | GSE17721_POLYIC_VS_PAM3CSK4_12H_BMDC_DN | MSigDB lists | GSE17721_POLYIC_VS_PAM3CSK4_12H_BMDC_DN | 184 | 59 | 17377 | 2626 |
SEPHS2,RAB14,SARNP,C19orf53,MUT,GORASP1,SRSF6,PMS2,ABCB10,CLCC1,AP3S1,TMEM165,GLRX3,PDXDC1,MFSD10,RPL23A,ATP6V0B,RRN3,NUP210,UTP18,ARHGEF1,CS,AKR1B1,ANP32A,CYB5R1,MRPL21,LRRC59,SLC35A1,NUP85,LYPLA2,TMX1,TIMM50,PREB,SRSF10,RPAP3,MOB4,NTPCR,SEC61B,RPRD1A,PSMA8,NOA1,BTG2,NSDHL,MRPL12,ADSL,SEPT7,MCM2,TSR2,DHX15,PRDX1,EIF3A,HNRNPR,RWDD4,ACADM,SNRPG,CHEK2,NAA60,SSSCA1,DDB1 |
| 5.243e-09 | -19.07 | GSE16522_ANTI_CD3CD28_STIM_VS_UNSTIM_NAIVE_CD8_TCELL_DN | MSigDB lists | GSE16522_ANTI_CD3CD28_STIM_VS_UNSTIM_NAIVE_CD8_TCELL_DN | 184 | 59 | 17377 | 2626 |
MBD1,RECQL,ANXA6,ADD1,MRI1,TCF3,MYH9,PTP4A3,MAN2B1,ETS1,TCF19,MIEN1,HMG20A,WRNIP1,NUP210,ARF5,MBD2,ARHGEF1,TAP2,CNN2,RNF135,SPTSSA,F2R,UBE2M,TPCN1,MTX2,FGFR1OP2,KCNAB2,CFL1,HP1BP3,CSNK1G2,CYTH1,PPP3CA,PHF20L1,TRAPPC9,HEMK1,FAM172A,MYBL2,POLR3GL,PACS1,OGDH,LY6E,PRMT2,FKBP3,SMAP2,GALNT2,ATAD2,UAP1,NSF,RBL1,CSK,DCK,LIMK1,PRPS2,STAT1,RNASEL,GEN1,ESPL1,CBX4 |
| 5.243e-09 | -19.07 | purine ribonucleoside triphosphate binding | molecular function | GO:0035639 | 1796 | 362 | 17224 | 2647 |
RAB14,ABCC10,TAP1,DHX8,GLUD1,UBE2I,EEF2K,KIFC1,CDK5,NEK6,RAB4A,ATP13A3,PDS5B,DNM2,UPRT,SUCLG2,MAST2,PLK3,RHOBTB3,NRAS,AKT2,PBK,KIF15,MKI67,DDX20,SMC2,AURKB,MCM2,RFC2,RAB22A,RAB2B,ARF4,MAP3K4,MKNK1,KIF18B,LIMK1,MYO18A,RNASEL,LONP2,PFKP,DDX42,DDX58,HSPH1,RECQL,CHTF18,RHOC,TRIO,GSPT2,PRKAA1,DHX9,RRM1,RAB23,CERK,KIF23,TOP2B,EIF2AK4,RTKN,DDX56,SMC3,MCM5,EFTUD2,CTPS1,MSH2,DAPK1,RTCB,PIKFYVE,GNAI2,PHKG2,UBE2QL1,CARS2,DDX28,COQ8A,MAPKAPK3,DHX29,NOA1,PGS1,GTPBP4,PIP4K2C,SEPT8,RIT1,PKM,ABCF1,MAP2K2,CCT8,RHOB,PI4K2A,XRCC5,ADSS,EPRS,NSF,CSK,CSNK1G1,DCK,QARS,ACLY,MAP3K5,CDK2,NRBP1,ACSF2,RHOG,KARS,ABCA3,TP53RK,RAB11B,RPS6KA1,RAF1,CHD1L,KIAA0232,ACTR3,RAC1,OLA1,TPX2,MYH9,EFL1,PRKACA,CBWD5,FLAD1,RAB21,PRKD3,ATP2A2,RALB,UBA5,ADCY9,CLCN6,SEPT11,TAP2,AQR,ARL5A,CDK12,ADCY7,CCT2,ULK3,ATP13A1,MAP4K4,TAOK1,PFKFB3,GALK2,PKMYT1,DNAJA1,RAB1A,MAT2A,DHX57,DDX17,KIF2A,RAD51C,HSPA4,JAK1,RAB24,GUCY1B1,HIPK2,CBWD1,PDXK,PPP5C,CSNK1D,TUBB,DYNC1LI2,RHEBL1,PRPF4B,POLQ,GALK1,ANXA6,TWNK,IP6K2,ATP5F1B,BLM,IFT27,PMVK,RAB11A,PIP5K1C,SRXN1,GATC,CBWD2,ARF5,TTLL12,MAP3K14,UBE2M,MSH6,SMC4,PDPK1,TK1,DDX24,GUK1,NEK7,BMS1,RHOT1,DDX39A,GUF1,KIF11,MARK2,MYO1F,GNA12,KIF18A,TTLL4,MAPK6,ASNA1,DDX5,DDX52,DDX47,UBE2E2,YTHDC2,MCCC1,CSNK2A1,UBE2Q1,UBE2Z,ABCB10,KIF2C,MAPK14,PAPOLA,ABL2,RAB8A,RAP1A,CDC42,EIF4A3,RAB35,TRMU,XRCC2,KIF22,RP2,EIF5,ABCC5,SRPK2,PLK1,LARS,SNRNP200,SEPT9,HARS,TLK1,CDC6,RAB5B,LSG1,STK17B,DHX15,RHEB,SEPT1,CHD3,IARS2,BAZ1B,QRSL1,ACTB,STK11,CHEK2,VPS4A,ROCK1,PSMC1,SEPHS2,UBE2D3,CDK13,THRAP3,RAB6A,CHKA,UBE2Q2,KIF13B,ALDH18A1,N4BP2,CSNK1G3,ABCC1,NTPCR,AACS,ACSL3,MAP4K3,EIF2AK1,KRAS,UBE4B,SEPT7,DAPK3,BBS12,MASTL,PSMC4,GNAS,PRPS2,NLRC5,RUVBL2,ATP5F1A,MYO9A,EHD4,PMS2,UCK2,SMARCA4,RRAGC,UCK1,CHKB,ORC1,ATP6V1B2,LYN,TWF2,CHD1,FARSA,PDK2,PSMA6,IARS,SAR1A,NVL,KIF14,SCYL3,ACSL5,CLCN3,CGAS,RAB7A,ARL5B,RAD54B,DAP3,ATP1A1,IDE,DHX16,CLK3,STK38,FASTK,XRCC3,MAPK1,ABCA1,RAD51D,KIF3B,NADSYN1,SHPRH,TOR3A,GNE,SCYL1,SMC6,ARFIP2,ARF1,MYO9B,CDK11B,CSNK1A1,SCYL2,PIP4K2A,GFM2,WRNIP1,KIF5B,GTPBP3,STARD9,FGFR3,GART,GRK2,ABCD1,DDX31,CAMK2G,MYO5A,CSNK1G2,RHOA,PRKDC,HELB,BTAF1,ATP2C1,ABCF2,TUFM,NADK2,PNPLA8,RHOT2,CDK11A,TARS,MAPK3,DDX23,HSPA1B,MFN2,RAB18,NEK1,UPF1,ATAD2,RPS6KC1,UBE2C,HRAS,HIPK3 |
| 5.354e-09 | -19.05 | V$E2F1_Q6 | MSigDB lists | V$E2F1_Q6 | 220 | 67 | 17377 | 2626 |
H2AFZ,RMI2,ORC1,STMN1,HNRNPA2B1,PCNA,CD3EAP,FIZ1,TRA2B,MCMBP,DNMT1,ARID4A,CDC5L,SP3,ZNF524,APH1A,E2F3,RRM2,DNAJC9,SREK1,CDC6,PBRM1,PKMYT1,MCM2,H2AFV,SRSF1,HNRNPR,RBL1,ZNF367,LUC7L3,ATE1,AP1S1,FKBP5,SASS6,GEN1,PRPF4B,CLSPN,ZCCHC8,TRMT6,CDT1,CTCF,SMC6,ASXL2,FBXO5,TFAP4,SMC3,SSBP3,MSH2,MRPL40,YTHDC1,NASP,PRKDC,ILF3,NFATC2IP,APPL1,POLR2A,CBX3,CAND1,SYNCRIP,ATAD2,DCK,PRPS2,KBTBD7,E2F1,NUP62,WDR62,RBBP4 |
| 5.382e-09 | -19.04 | Intra-Golgi and retrograde Golgi-to-ER traffic | REACTOME pathways | R-HSA-6811442 | 179 | 61 | 10287 | 1696 |
KIF3B,TMED7,GOLIM4,SYS1,COPA,SCOC,DYNLL1,COPE,DCTN2,VPS45,VTI1A,KLC1,KIF23,ARFIP2,AGPAT3,RACGAP1,TGOLN2,KIF2C,TMED3,RAB6A,ARF1,COPG2,RIC1,COPB2,MAN1A1,KIFC1,KIF5B,NAPG,ARF5,KIF13B,KIFAP3,KIF22,NAA35,GCC1,TMED2,KDELR1,DCTN1,GCC2,CYTH1,RHOBTB3,KIF15,COG1,BICD2,RAB1A,STX16,GOSR1,KIF11,ARF4,KIF2A,MAN2A2,RAB18,GOLGA4,GALNT2,KIF18A,SURF4,KIF18B,NSF,TMED10,SNAP29,STX18,DYNC1LI2 |
| 5.397e-09 | -19.04 | GSE22140_HEALTHY_VS_ARTHRITIC_MOUSE_CD4_TCELL_DN | MSigDB lists | GSE22140_HEALTHY_VS_ARTHRITIC_MOUSE_CD4_TCELL_DN | 193 | 61 | 17377 | 2626 |
CCDC93,NCOR2,GNPDA1,TMEM41B,CTCF,SIKE1,GGA2,RGS2,UBE2I,MAPK14,ITGB5,TUBGCP2,LMNA,ANKRD28,NDUFV1,MLX,IARS,SEC24C,ARHGEF2,MAP3K14,ZNF710,LPCAT1,KCNAB2,SMC4,GPX4,SRP72,ACP2,AGGF1,GBA,ATP6V0A1,MEF2D,USP22,KCNQ1,PLEC,PDE3B,PDHX,RBM38,POLR2A,RPA1,AKAP1,RXRB,MYO1F,MAN2A2,HHEX,GNA12,TRAM2,SERTAD2,AHNAK,GOLGA2,POLR2J,CSK,PFDN4,SETD3,HIPK2,OAZ2,DCAF11,MRFAP1L1,WIPI2,RRS1,LTA4H,IGBP1 |
| 5.448e-09 | -19.03 | GSE14415_NATURAL_TREG_VS_TCONV_DN | MSigDB lists | GSE14415_NATURAL_TREG_VS_TCONV_DN | 171 | 56 | 17377 | 2626 |
PTMS,CLSPN,KDM4A,CHTF18,CENPF,CDCA3,RRM1,CDCA8,TPX2,KIF23,NUF2,PMF1,FKBP2,BLM,NCAPG,STMN1,SPAG5,FBXO5,CCNA2,ATP2A2,DUT,MCM5,KIF14,PRC1,MRPL34,CDC25B,CENPM,GNAI2,MYBL1,TACC3,GINS1,PLK1,TK1,ASPM,PBK,KIF15,RRM2,WDHD1,CKAP2L,BRCA1,SMC2,MCM2,KIF11,MTR,ABCF1,ASF1B,RAD51C,BIRC5,NEIL3,CEP55,ACTB,FKBP5,HMGB2,SPCS3,CCNB2,MAPK1 |
| 5.586e-09 | -19.00 | large_intestine | COSMIC cancer mutations | large_intestine | 17068 | 2572 | 17385 | 2587 |
HECA,ZBTB10,ABCC10,HEXB,TGOLN2,CCNL2,FBXO22,EEF2K,THAP4,RAD23B,ATP13A3,DNM2,ZNRD1,FTSJ3,USP34,CCDC57,ERCC1,NRAS,EHMT1,KIF15,HNRNPF,WDHD1,MIER2,DIDO1,MCM2,RAB22A,SMAD2,MID1IP1,RPS27A,MYO18A,OGT,MPV17,COX5A,SMAD1,ZNF75A,ANXA11,SLC25A33,ZNF720,SEC61G,GGA1,MUM1,CCZ1,TRIO,CUTA,RAB23,KCTD17,HAUS4,EIF2AK4,APH1B,PARN,CDC73,MYL6B,ATG4A,TMEM179B,ERV3-1,PDXP,SMC3,C4orf3,GEMIN4,MVP,NUP85,PPP6R1,PABPC1,NSUN4,PPA1,IFRD1,AGGF1,FOXK1,RBM42,GTPBP4,MAP7D1,MRPL16,ELK1,EIF4H,RDH11,MAGED2,KPNA1,ETS2,TYW5,WIPI2,RUFY3,PDLIM5,ACSF2,RHOG,EXOC3,STARD7,C5orf30,VTI1A,INO80E,SLC35B2,LCLAT1,RCOR3,CPNE3,KIAA1147,RBM23,ZNF420,AHCTF1,TBC1D22A,TBC1D14,GMEB1,NSFL1C,SEPT11,ZNF226,GPD1L,ZC3H3,ARL5A,PDCL3,SNX8,ERMP1,EID1,IDH3A,POLR2D,HTATIP2,MEF2D,TMEM147,GSTCD,TANC1,MAT2A,VPS26B,CORO1C,NSMCE2,CAMKMT,PPP5C,PITRM1,TUBB,COMMD10,ZNF445,SRSF6,HABP4,CCM2,FLOT1,BTN3A1,ATG2B,ABHD14B,PPP1R3B,GOLM1,ZBTB45,HUWE1,ZNF260,NAA50,ANXA5,LTN1,KANSL2,UBE3B,NAP1L4,ZNF710,ST8SIA2,RPL22L1,MED22,SPTAN1,STAU1,DDX24,TCTEX1D2,TACC1,MRS2,LDHA,HEBP2,LLPH,RAB3IP,TTC33,PICALM,SH3BP5,SLC19A1,ACOX1,FAM3C,AEN,PARP10,YWHAH,THAP5,GPATCH4,FAM129A,TRIM11,YTHDC2,SNX15,RBM8A,ENSA,NENF,SND1,RUFY1,TRIM65,ZER1,PRNP,KRR1,RAB8A,NUP210,NT5DC1,NOC2L,EIF5,TACC3,RYBP,VPS13B,PTPN18,MIOS,SNRPB,MBLAC2,CDC6,UTP3,PBRM1,ODC1,USP21,TRAM2,FBXO28,BCL7C,ARRDC1,ADAM9,DVL1,NUMB,ZNF564,FUBP1,C1orf74,CTU2,PARP12,ZCCHC9,CENPF,LAMTOR3,CHCHD2,NCKAP1,LYRM2,RSAD1,TNS3,SUB1,RINL,SSBP3,KIF13B,MBD2,XPA,AHCY,RBM3,GLE1,MRPL48,LRSAM1,HDHD2,NTPCR,NSDHL,AMD1,CAMSAP1,ZNF761,METTL22,ICAM2,STYXL1,APPL1,BBS12,ANKRD46,RXRB,SDHB,PCM1,GALNT2,TMEM168,NLRC5,RUVBL2,BTBD10,MYO9A,CCNB2,USP7,GLT8D1,RPLP2,SUCLG1,ARID2,TMX4,SLC2A1,ATP6V1B2,PCBP1,LYN,BCAP31,VAV1,TMEM69,MRPL50,PSMA6,ZNF473,ZNF302,BRPF3,TARDBP,BCAP29,CTDSP2,PRPF19,PPIF,KDM3B,MND1,CLCN3,BIRC3,RAB7A,ANKRD33B,PPIE,CHMP2B,VDAC1,EIF3H,TMEM201,GLOD4,IDE,DHX16,UHRF2,XRCC3,CHMP4B,PARD3,BCL2L12,C19orf53,MCM10,KLHL21,PDAP1,CDCA8,TMX3,GTF3A,ARF1,SLC12A9,TUBGCP2,DNAJB9,HOMER1,WBP1L,POLR1B,RNF5,RBM15B,PPAN,RHOA,RPRD1A,BTAF1,TOP3A,ARHGEF12,PCGF1,DDX23,RAB18,CACNB1,TRIM26,PDCD6,ATP6V1D,L3MBTL3,FAM110A,NEIL3,CTBS,BBX,IMPDH1,TAF12,NR2F2,PGAM1,HIPK3,IFI16,TXN,NUP188,H2AFZ,PNISR,TMEM203,PRKCSH,USP39,UBE2I,PARK7,SLC25A37,ASPHD2,ZNF428,RAB4A,TRA2B,SUCLG2,CISD2,TAF5L,SMARCE1,ZNF800,CDC5L,ZNF524,SGCE,OSBP2,NSUN2,USP22,CLNS1A,EIF3A,ZMYM3,DOT1L,IWS1,ANKRD10,WAS,KIF18B,TPP2,C1orf109,ZMAT3,B4GALT2,PRPF38B,RECQL,C9orf78,EWSR1,GADD45G,RRM1,ACAP1,B4GALT1,CYCS,FAM136A,SUPT7L,TMEM165,CNOT3,NPLOC4,SPAG5,WDR48,RTKN,CEP104,EXOSC7,KLHL5,LRRC8D,PPP4R1,MSH2,PIGG,FBXL7,OSTF1,MRPL40,TNRC18,SYTL3,FAM171A1,APOL1,EIF5A,GCC2,PRIM2,ELL2,RDH10,MFNG,RPS24,GORASP2,CAPZA2,ADRB2,CCT8,MTR,PHF6,PFDN5,SLCO4A1,TTC13,GOLGA2,RBMX,MED15,PIAS2,APPL2,SAMD8,CDKN2A,NUDT3,ZNF511,ATXN3,RAF1,KIAA0232,C2orf49,CD320,EPM2A,CCNA2,MTMR4,BRI3,TP53BP2,AQR,RBM12B,ILKAP,CDK12,SAP30,BRD4,DRAP1,NARF,LRRC8A,ELP4,ABHD11,PKMYT1,ASB13,SERP1,TRIM28,SUPT16H,EIF3K,CHMP4A,CBWD1,ATF6,XRCC4,ADAM23,PRPF4B,NDUFS1,DEPDC1,MECP2,SECISBP2,HMG20A,WWP2,JAKMIP1,SLC25A36,CCNK,DNAJC8,ELP5,AXIN2,CITED2,JMJD4,ANKRD37,KAT2A,TMEM126B,RABIF,ADSL,PACS1,BMS1,KCNQ1,OTUD3,ARSK,MACF1,KIF11,COMMD4,KLF6,SMAP2,FADD,SH3GLB1,MYO1F,CBX3,TMEM127,INF2,PPP1R11,DUSP11,DDX5,WDR62,TAF6,ESPL1,PURA,DDB1,DEF6,IPO4,FAM83G,UBL3,NAT9,PIGM,LYRM4,GPR132,UBE2Q1,PTP4A3,BRIX1,MRPL19,ZNF696,SF3B2,PCYOX1L,CDC42,SYNM,GOT2,JAZF1,HADHB,RPF2,SLC35C2,CNNM3,CARM1,SRPK2,WDR41,LARS,ZCCHC10,CCDC138,LRBA,TMEM216,SUMF2,KMT2C,OGFR,PRPSAP1,ASF1B,RPL37,MAN2A2,EIF4ENIF1,NIP7,U2SURP,MIA2,ZNF268,VPS4A,ATP6V0E1,PPP1R2,PM20D2,XPNPEP3,RGS2,LYAR,FAM89B,POLR2I,TRAFD1,SUGP2,GBA,EIF2A,SYVN1,DAPK3,ARHGAP15,MASTL,UAP1,NFIL3,FN3KRP,YWHAZ,CTSA,TMEM14A,TOB1,TSEN15,ADNP2,TCF12,PRKAB1,MDH2,SMARCA4,ORC1,RRN3,UBXN2A,IARS,CD3EAP,KIF14,EXOSC1,CS,CLTB,DNAL4,CSTF1,POU2AF1,UBQLN4,NXT1,HPDL,PGGT1B,SELPLG,SMU1,ATXN1,GLO1,OGDH,BICD2,CADM1,EDEM2,HERPUD2,TOLLIP,FANCE,MBD3,PDHX,RPS9,ALKBH6,SURF4,DUS3L,ARNTL,ANP32E,FKBP5,TMEM101,CCDC125,ABCA1,PDCD2L,GCLM,RAE1,DCTN2,NUP54,CHIC2,PAWR,MXD4,DCUN1D4,PIP4K2A,XPR1,FERMT3,KIF5B,KLHL20,SEC24C,RRBP1,ARHGEF2,ANP32A,LDLRAD3,C12orf75,STAT3,MYO5A,NIPAL3,AMPD2,TXNL1,PHF20L1,DCAF6,FAM49B,TMEM39A,ATP2C1,RFFL,COG1,RCOR1,PRMT2,TFEB,LEMD2,UPF1,ELMO1,ZC3H7B,DTX4,ZMIZ1,TERF1,HRAS,CCDC93,FGFR1OP,TMED7,PIGQ,AGPAT1,CNTROB,PPP1R16B,MIS12,GSDMB,TTC9C,PDS5B,NUP153,SENP1,PGAP2,TMEM115,PLEKHM3,DCUN1D5,PLEKHF2,BRMS1,PWWP2B,TRIM47,WDR11,AXIN1,SMG9,TRIM52,LONP2,NDUFV2,PHF23,CERK,SLC4A2,EZH1,ITGB5,LMNA,MCTS1,DDX56,EIF2S2,SLC38A5,FOXN2,CARS2,PRRC2A,C16orf72,RB1CC1,ZMYND11,PGS1,MYBL2,UHRF1BP1,SRSF5,MPG,MATR3,CYB5A,NCDN,POLR2J,SETD3,TEX30,PTAR1,CNOT6,NDE1,EGLN1,ZNF207,ANKRD27,PPP1R37,ABCA3,SARNP,IVNS1ABP,RMI2,MON1B,TMEM97,NIT2,NUF2,ZNF267,TCF19,TMEM161B,KTN1,APP,PRKD3,CLUAP1,ATP2A2,UTP18,GRSF1,DUT,ZCCHC2,ANAPC7,RNF19A,FAM76B,CLN6,TMEM9,GCC1,RNF169,ADCY7,ATP6V1G1,ENPP4,RNPS1,CDCA2,FKBP3,GPR137,DDX17,CHCHD3,PEX5,CDC16,HIPK2,MBOAT1,TICAM1,PDXK,ZBTB11,ANXA6,TMBIM4,GMCL1,UBE4A,IL21R,ETS1,WRB,ZNF92,PNO1,CAPN2,ADD3,SUV39H2,TTLL12,TPCN1,TMX1,HNRNPM,LYPLA2,MFSD12,LDHB,PPP3CA,NUDT8,POLK,JTB,EMP3,MTMR12,ZP3,PDE3B,KIF18A,CCDC6,WNT5B,MAPK6,C4orf46,LY75,SLC25A19,RGL1,PSAP,WDR76,IGBP1,FAF1,SNAPIN,COX15,THOC1,AGRN,GNPDA1,GPBP1L1,PPP1R15B,CSNK2A1,EBNA1BP2,GIT2,BIRC2,ATPAF1,DLG5,ABL2,XRCC2,ZFYVE27,MCMBP,PTPRK,CDC37,SP3,METTL1,EXOSC6,HARS,GMFB,ESYT1,ANLN,RAB5B,RHEB,DPYSL3,TBC1D17,TIMM13,CDCA4,TONSL,NRM,NAGLU,ACTB,ZNF45,TMUB1,CTCF,ASAH1,DOCK11,CRLF3,ASXL2,LRRC14,NUS1,SLC27A4,AFF1,MDFIC,MAML1,CYTH1,NQO2,UTP15,EIF2AK1,EIF4G2,ZDHHC3,MOSPD3,ITPRIPL1,CDC27,SNAP23,TBPL1,PRMT7,KCTD7,NDUFA5,CYLD,UGP2,DYNLL1,COPE,HCFC1R1,ZADH2,GGPS1,RPAIN,RAD23A,ABRACL,ATP6V0B,PDK2,STRBP,DUS4L,MRPL34,PDCD2,SAP30L,CLPTM1,SLC39A9,RPL29,RPL35,BTG2,DNAJC9,FRAT2,MTMR6,NFATC2,KDM1B,ARL5B,USP36,CCDC127,MRPL2,ATP1A1,CLK3,MAFK,PSMD3,NDUFA11,CEP55,ZNF436,DNAJC17,NCOA1,SLC25A39,ZC3HC1,ZNF146,ATXN7L2,CDC40,SMAP1,GOLIM4,RRP15,DAP,GNE,SMC6,ARFIP2,NKRF,CHAC2,BZW2,WRNIP1,TMA7,SS18L1,CENPM,PTGES3,CAMK2G,MLEC,ZNF202,PPWD1,FAM50B,RHOT2,NEU1,TPD52L2,GOLGA7,TWSG1,GLG1,PGRMC1,FAM126A,RPS6KC1,UBE2C,PPCS,NDUFB6,TMEM41B,ZDHHC8,PLXNA1,CCNB1,SLC20A1,COMMD6,ABHD14A,POLR3K,C14orf119,ASAP2,SNUPN,CNPY4,TFG,PLCL2,SEH1L,ATG9A,PBK,MKI67,DDX20,AMDHD2,GALNT7,SLC17A5,CCNF,FOXRED1,RBM47,PTER,WDR4,DHTKD1,TRAF5,HDAC2,PWWP2A,HSPH1,LIME1,MAPRE1,CHTF18,ADO,KIF23,SLC35B1,NOTCH2,PMF1,COPG2,JMY,FKBP1A,SLC31A1,SNX18,ATIC,CTPS1,ATP6V0A2,PIKFYVE,RNF135,LPCAT1,EEF1D,TMED2,PHF10,FTL,DDX28,ZNF84,SIGMAR1,PIP4K2C,FAM133B,RIT1,PLEC,KDM3A,SF3A2,FAS,EPRS,ZNF777,TMEM54,QARS,PPP3R1,TCOF1,NRBP1,CABLES1,DNMT3A,RWDD1,CKLF,TRIP10,SF3B1,RPS6KA1,CAST,SUZ12,RAC1,GPR89A,OLA1,SNN,GNB2,FLAD1,APLP2,KDM2A,TNPO2,CDKN1B,TALDO1,GPX4,ATP13A1,RFC3,MAPRE2,ERF,CUL3,SLBP,KIAA1586,H2AFV,POLG2,GAR1,PSMB9,DHX57,NSA2,HSPA4,MRPL55,JAK1,TBL3,GOLGA8A,SEL1L,H2AFX,KLHDC4,B4GALT3,PDCD11,ATMIN,POLQ,POU3F2,OTUD5,NCOR2,ANKRD13D,PKP4,SCAMP3,BABAM1,CDCA3,SLC25A12,BLM,TMCC3,GTF2F1,RPL17,CRAT,AHSA1,PRC1,UPF2,COPS7B,SLC38A10,CNOT6L,CNPY3,UBE2M,IFT46,TMEM160,TSHZ1,ZFP64,STRIP1,DENND4C,DENND1B,WDR18,RPL8,ILF3,LRRC1,RHOT1,MARK2,TSR2,ECH1,PRDX1,PLD3,NUCB1,FBXO21,GNA12,C1orf131,PRDX3,PFDN4,HNRNPH3,STX18,TFDP1,KHSRP,ASNA1,CPEB2,SSSCA1,BYSL,VPS29,S100PBP,MIB2,IER2,PTMS,NOP2,UBN1,DCAF15,NF1,FLYWCH2,ALKBH5,MOGS,UBE2Z,TAF6L,MAPK14,BECN1,SNAPC4,RNF103,BCAT2,MBD4,C18orf32,METTL14,IMPAD1,ZNHIT6,RCSD1,PHTF1,SRI,KIF22,ZBTB22,NFU1,OGG1,TRIM14,ELOF1,COPS8,FYTTD1,TRIM8,RRM2,SOX4,ABHD5,UBTF,CXXC4,PAF1,UEVLD,SPATA2,PQBP1,IARS2,ATXN2L,GALNT10,STARD3NL,RPS15,PIGN,AGTRAP,CIB1,XPO7,SRRT,ZNF449,CAPZA1,GLTP,BCL2,KIFAP3,N4BP2,HP1BP3,VOPP1,THNSL1,ISG15,CAND1,C22orf46,GNAS,TSC1,RBM25,CDCA5,ZFP90,NANP,RBBP4,ZBTB24,SMARCD1,MBD1,WASF2,MMACHC,TOMM20,IFI27L1,GNPNAT1,MPHOSPH8,HNRNPUL2,CHD1,MEAF6,C2orf68,CCDC50,AKAP8,PARL,RPN2,CHTOP,FAM3A,F2R,SCYL3,TMEM14C,ABI1,HTRA2,MOSPD1,RLIM,FAM172A,ZNF500,PSMB7,NLN,WIPF1,BOLA1,BUD13,NDUFB1,PEF1,EIF3G,BTBD1,TAB2,CHCHD1,TULP3,WDR59,CANT1,SCARB1,GAS2,USP11,SMURF1,TSPAN5,PPP2R2D,CDS2,MAGEH1,MRPL42,EYA1,CDK2AP2,MRPS26,LETMD1,KLF13,HDDC2,RGS1,MAN1A1,FBXO5,GART,PELO,TANK,BRD7,MRPL11,SAMD4B,ZDHHC18,GTF3C6,POLR3GL,WDR81,MEN1,ZNF407,MFN2,COX8A,ZRANB2,MBD6,SRSF3,ATP6V1C1,IDH3B,TATDN1,TSC2,LACTB2,CMTM6,RBM4,ANKRD39,ZNF275,RPL23A,CDKN2C,NAPG,USF1,DNAAF2,MECR,AP1M1,UPRT,CRY2,ECD,RNF26,TIPARP,LRRC59,ANKRD9,MGAT5,RHBDD2,BAK1,ZNF559,RHOBTB3,GABPA,NUTF2,WBP1,GINS4,ARF4,KRIT1,BOLA3,AHNAK,RAD18,PDRG1,RNASEL,CHPF2,OAZ1,SMNDC1,PDCD4,NXT2,HIVEP3,KIAA0100,CLSPN,RHOC,DHX9,PDCD7,PSMD9,HAUS2,COPB2,CD59,TFAP4,RNFT1,RIMS3,MEGF8,FBXO7,EFTUD2,MRPL21,CPSF4,PHKG2,LUC7L2,SRSF11,EIF3L,MTA2,TYW1,USP10,ITM2A,SSR2,BCLAF1,MTX1,SFXN5,FNTA,PDLIM1,TXNDC16,TMEM159,ZNF830,MRPL3,ALS2,TRIM41,KARS,NQO1,POC1A,PTTG1,ANK3,TPX2,TBC1D13,DAZAP2,STMN1,GLRX3,C19orf48,CBWD5,REPS1,ABHD16A,FBXL6,SH3BP1,MTA1,UBA5,CLCN6,INTS12,C8orf59,RPRD1B,SZRD1,CGGBP1,CPNE1,SEC61B,POLR2L,FAM118B,GOPC,CRNKL1,E2F3,CIRBP,RPL38,PFKFB3,GORAB,RAB1A,GIGYF1,TMEM184C,PPP2CA,KIF2A,CCDC14,LSM6,RNF38,DMWD,SNRPG,CENPBD1,USP13,MZT1,ZFP91,TRMT6,IP6K2,WDR5,SLC25A43,IFT27,PMVK,RRP36,NEIL2,SRXN1,RPA2,PSMD2,CLIC4,PDCD10,ITGB8,CBWD2,COQ4,ARF5,ARHGEF1,FBXL19,GTF2H2,TTPAL,UTP20,MAGT1,GPS2,DBI,MRFAP1L1,SSNA1,CD81,TMEM131,WDR13,FANCI,PAPOLA,CREM,FANCL,TET3,GLIS2,IL6ST,INTS1,POP7,SLC44A1,MTPN,ASB6,PLK1,RPP25,SEPT9,CELSR2,RBX1,APH1A,RAD51AP1,ZBED5,CKAP2L,PSMG1,UBE2V1,IL12RB1,EAF2,KRTCAP2,LUC7L,LSG1,NECAP2,C1orf122,ALG3,TRIM4,AGPAT2,CHD3,ZNF367,E2F4,PRPF4,KPNA2,BEND6,CLN3,DNAJC30,FAM208A,NGLY1,POT1,MYL12B,CCDC137,RMND5A,HJURP,PHB2,FAM53C,DNAJB2,NKD2,SDC2,KLC1,CDK13,ADCK5,COX4I1,RAB6A,DNAJB1,ARID1B,C1GALT1,MLX,UBE2Q2,CCP110,ZNF746,ARL6IP1,CTR9,NIPSNAP1,ABHD2,DCAF8,ACSL3,LDB1,MAP4K3,ARMC8,RBM38,IRF5,NMT2,RPL36,HAUS8,MBIP,ORMDL2,COX7A2L,ZDHHC7,FAM122A,SIL1,DTD1,UNC13C,BCCIP,SART1,TRAF7,NDUFAF2,TOR1AIP1,ZNF416,LAGE3,TM9SF3,ZFYVE21,RRAGC,ZNF121,OIP5,NRF1,WDR44,PIN1,PPME1,EFCAB11,RPAP1,CABLES2,TOP1MT,LMAN1,AHCYL1,STRAP,SPSB3,ZNF583,SNX25,ARHGAP17,POLR2G,KIAA0040,ZNF780B,PPT1,NUP155,DCLRE1C,MRPS14,RHBDF2,SUGP1,RBL1,FASTK,UBXN2B,STK38,AP1S1,SPRYD4,SLC22A23,H3F3A,CHID1,SMAD4,RAD51D,SLC30A9,NADSYN1,UNK,CMAS,HMGN3,NCAPG,SCYL2,FZD6,HERC3,GTPBP3,CTSS,ORC3,RNLS,YTHDC1,ACP2,CSRP1,HMGN5,METTL5,ABCF2,TUFM,RANGAP1,PNPLA8,HAGH,API5,ZFR,SEC23IP,E2F1,USP20,TMEM219,RBPJ,MAX,PDCD6IP,LUZP1,GXYLT1,ADAM10,CXXC1,TSC22D3,AP3M2,CUL1,GYG1,NANS,OAT,MYEF2,ANKRD26,PA2G4,NOL11,FIZ1,ZNF200,MARCH2,SLC26A2,SRP72,KLF10,LACTB,CBFB,RFC2,RAB2B,PRIM1,MAP3K4,HHEX,RPS14,LUC7L3,MAP4,MRPL27,BTF3,PTPDC1,CCDC59,NMD3,PTOV1,COX5B,DNAJC5,SCOC,DHPS,POLR2K,ANKH,C16orf87,VAV2,PRKAA1,GSPT2,DLGAP4,TATDN3,PXMP2,PRPF39,PSEN1,ZNF79,PDXDC1,VPS25,NDUFS7,YY1AP1,C12orf10,FAM192A,RPN1,LHX8,ARPC5,ZNRF2,DAPK1,TPST1,PIK3IP1,CYC1,SOCS5,FDFT1,PIGT,WDR1,EMB,ZNF574,C1orf35,EXOSC9,ARID1A,PTTG1IP,C9orf40,FXR1,GOSR1,MAP2K2,TWISTNB,AKAP1,XRCC5,HMGN2,PI4K2A,SEC31A,CAT,DERL1,HSPBP1,MTHFD2,CEBPG,ARAP1,FAM83D,USP32,CABIN1,SMPD4,GPI,CYTIP,TP53RK,REPS2,RAB11B,UROD,SLC39A13,POMP,BCL2L1,NUDT19,DECR1,RALB,SIAH1,LPIN2,ADCY9,SOCS6,MRPS27,TTC3,RNASEH2A,CFL1,ANKLE2,CDC123,OAF,VDAC2,EDF1,ERC1,EML4,AMZ2,ANKZF1,ZNF282,RAD51C,DSN1,DDOST,HINT1,DGCR8,SAFB,HAGHL,LMBR1,RWDD4,FTSJ1,NCLN,BEND3,EYA2,DYNC1LI2,B4GALT5,SLC41A1,MANBA,TKT,FAM76A,CBLL1,ARGLU1,LANCL1,POFUT1,FAM8A1,HEATR5B,HLA-A,EBP,RFWD3,NDUFA2,FUT8,FJX1,BTF3L4,PTPN11,MRPL54,FEM1B,RPL19,CNN2,NDUFA3,MTX2,MSH6,PDLIM2,LONRF3,RFXANK,FBXO9,GUF1,RPL32,ZHX1,OAZ2,NDUFS5,WDR91,GPR89B,HIGD2A,ZBED3,RORB,POLA2,ZNF76,MTX3,COPA,UQCR10,HMGXB3,PHRF1,ABCB10,COMMD5,MAP1LC3B,DST,SIVA1,RAB35,GPATCH1,TCEA1,DRAM2,DEAF1,TRAPPC13,SNRNP200,NCK1,LAP3,VHL,SREK1,ARHGDIB,PITPNB,HSPB11,BRWD1,PPM1G,SH3GLB2,CRCP,BAZ1B,CAB39,ACBD4,STK11,CLU,CHEK2,ZSWIM3,TSTD2,CHPT1,MRPL13,DCAF5,CAPN1,UBE2D3,NSMCE4A,PPP1R12A,ZCCHC8,GORASP1,UBXN1,NACA,C19orf25,PCSK7,EPN1,RPL15,THRAP3,TTF1,QSOX2,PRPF18,NUP205,CHKA,DTL,MED10,ZRANB1,MCPH1,SLC12A2,ATP6V0D1,CSNK1G3,CREG1,NUDT4,RPL6,VKORC1,SLTM,EVC2,KLHL15,SIAH2,SLC16A1,EHD4,SNRNP70,C11orf1,APOL2,N4BP2L2,SNX27,CHMP2A,CORO7,FEZ2,PMS2,UCK2,UCK1,CLCC1,EXT2,MXD1,USP5,HNRNPA2B1,SAP130,NVL,PPP6C,CYB5R1,ZNF770,EBAG9,RNF25,PCGF6,METTL2A,FAM72B,PON2,HNRNPR,STAT6,HPS5,MAPK1,BRD9,TMEM33,NAT14,DNAJC2,TRIP12,SHPRH,SCYL1,VPS45,MYO9B,GFM2,SPPL2A,FASTKD3,FGFR3,MZT2A,PPIG,ZDHHC13,TMEM99,H2AFY,ATG13,NDUFS8,ERI3,FBL,SLC35A1,FRMD8,MICAL3,TGFB1,B3GALT6,ELOVL5,HEMK1,TIMMDC1,HELB,PSPC1,MIER1,SCFD2,NDRG3,ARL17A,CDK11A,MTMR3,MEGF9,ACAT1,CENPT,PLOD3,RAB3IL1,ZSWIM6,RAB14,ADD1,MRPS15,KDM4A,XIAP,DHX8,GLUD1,ANKRD23,PABPC4,CALM2,CDK5,PSMD1,NEK6,NSRP1,RABGAP1L,SRSF4,FNIP2,KCNAB2,PCBP2,MLST8,PLK3,ZNF672,HSDL1,MRPL43,TOPORS,MCL1,SMC2,PPFIA3,ICMT,SLC50A1,STOML2,LIMK1,ZNF689,PRDX5,ATE1,MLYCD,ATP6V0C,ST3GAL2,FBXL3,TFDP2,E2F2,PFKP,AAAS,DDX42,SSRP1,MRPL9,MRPS2,STRN4,TOP2B,ZNRF3,TMED3,DDRGK1,RAVER2,GNS,INTS7,INPP5A,MCM5,PHF14,ZNF326,UBE2QL1,NAGPA,TIMM8B,ETV3,TSPYL4,TSPAN31,DHX29,TEX10,MAN1B1,RPS10,CBFA2T2,ABCF1,RHOB,LRRC14B,DTWD1,PTPRF,SCARB2,OSBPL11,CCDC86,DUSP3,SLAIN1,MDH1,HEXA,RNF139,SNX14,ZNF296,TRERF1,UBR2,CHD1L,ACTR3,WDTC1,MYH9,CREBL2,NIPA2,PRKACA,SAFB2,ANKIB1,STAM,ARL6IP6,RAB21,SP100,ZKSCAN1,DDA1,NUP107,ANKRD13C,MAVS,CEP63,TMEM136,RBM15,ATF2,DCTN1,SHOC2,PSRC1,MAP4K4,WBP2,ATP6V0A1,NUSAP1,NDUFA7,DNAJA1,TAZ,C19orf54,TAF2,SEC61A1,WDR7,RPLP1,CBLN2,RBMS1,FUS,GEN1,LRP8,COIL,LRCH1,GALK1,ZNF786,RPS2,SESTD1,TRAK1,JMJD6,SIKE1,AKT1S1,KRI1,FBXO3,ERH,GATC,NDUFB4,PPP1R8,PRDM4,GTSE1,GEMIN6,DCP1A,SGCB,S100A6,IMPA2,NUDC,PDPK1,TK1,GUK1,TNFAIP3,GALC,ZNF512,KIAA0930,MRPS10,DDX39A,RPA1,ZNF862,ZNF180,KEAP1,POLE,TATDN2,PITX1,CAPN7,LRPPRC,PML,HMGB2,USF2,ANAPC4,SRM,DDX47,MCCC1,CDC42SE2,S1PR2,CDIPT,SEC16A,SSR1,LIN9,PCNA,ZNF639,TRMU,PIK3R2,ETV6,TXLNA,PPCDC,FAM86C1,MYBL1,MRPL32,CCAR1,ABCC5,PBXIP1,BAZ2A,TLK1,MRPL12,EZR,LNX2,LRP5,BRCA1,PRKRA,STX16,EPB41,OPTN,SEPT1,SOCS4,QRSL1,PIEZO1,OSGEPL1,GLCCI1,NUDT11,NAA60,GEMIN7,SEPHS2,LZTR1,RACGAP1,PPP3CB,B4GALT4,RLF,RAPGEF6,SNRNP25,RB1,VASP,MED8,VMP1,PPIL2,MEA1,TIMELESS,AHDC1,ALDH18A1,TMEM8A,ABCC1,PREB,TRAPPC9,AACS,MEMO1,KRAS,RTF1,UBE4B,NFATC2IP,LY6E,ARPC1A,ZNF174,PSMC4,GOLGA4,SYNCRIP,PALB2,PRPS2,NIPA1,TIGD2,RNF114,FOXM1,MRPL39,XAB2,SUMO2,DUSP22,COMMD8,RPL11,CSDE1,MDM2,CORO1A,MINPP1,METTL9,POC5,DVL2,GM2A,PSMA8,COQ10B,CPOX,TIGD5,SLC26A6,CYP20A1,PRPF3,TXNL4A,RPSA,SRSF1,DNAJC10,SCAP,ZNF700,PLEKHG4B,TIMM17A,TOMM6,FAU,LTA4H,AP2S1,USP53,INTS2,CTDP1,MIF4GD,CDT1,ARID5A,SUMF1,GGA2,AP3S1,CSNK1A1,RMI1,TFRC,PTPN2,IRF4,STARD9,GSTK1,NDUFV1,SLC1A4,CWC27,SLC35B4,DDX31,ABCD1,RPAP3,CNTN5,SNX2,ZMYM5,CCDC34,CHCHD6,BSDC1,KPNA4,CDKN2AIPNL,FBXO41,BIRC5,TFE3,SNAP29,CDCA7L,PKD2,ACADM,CHMP7,SAT2,GCSH,ZNF496,TMEM109,TAP1,YTHDF3,NHLRC3,IKBIP,EIF1B,ELMOD2,KIFC1,DBNDD1,CYB5RL,PARPBP,RNASEK,CDC25B,PRADC1,DNMT1,NOL12,ORAI2,USO1,AKT2,NOL8,GNG7,AURKB,MCFD2,SLC25A5,ZFAND5,MAK16,STT3A,TMED10,PSMD8,EIF2D,ITGB1,PTPN7,UQCRH,RRS1,ARRB2,RTN3,ZNF598,SVIP,DDX58,WSB2,PPIB,MUT,GMFG,HLA-E,NDUFA4,MAN2B1,METTL3,CFLAR,NDUFS4,RNF121,MEX3C,KLF16,HDAC7,DAD1,BDH1,PCYT2,GNAI2,ANKHD1,MORC3,TERF2,KCTD20,SEPT8,DCTD,PKM,TOMM40,PATL1,ADSS,SERTAD2,SERF2,ZFP92,NSF,DCK,ERGIC3,ACLY,LPCAT4,VCPIP1,YY1,MAP3K5,PPP6R2,PPP6R3,RNF14,CDK2,ZC3HAV1,SYS1,ZBTB37,URB2,EIF3D,MAGED1,KLHL18,ADPGK,SLC25A44,AP1B1,SDHA,PAIP2,PHC2,CRKL,MOAP1,TERF2IP,CYHR1,ZNF75D,SHC1,UCHL5,NAA35,TMBIM1,CCT2,CDKN2AIP,MKLN1,HMGN4,LYRM1,GALK2,CDC23,SHCBP1,AP4E1,PRDM11,VEZF1,PPP2R5A,ACYP1,STAT1,PPA2,TRIM32,RHEBL1,R3HCC1L,C1orf112,MRI1,TCF3,BRAP,AGPAT3,MYNN,SDF2L1,SPR,RAB11A,REEP5,FOXO3,MAD2L2,CCDC28A,PIP5K1C,RBM17,MAT2B,PTEN,CENPJ,TAGLN2,OSTC,CREB1,PACS2,NCOA2,SMC4,RNASEH2C,NEK7,NET1,PARP4,TBRG4,ANAPC2,RPL27A,YIF1A,SGSH,HGS,TTLL4,SLC38A7,MFAP1,CCDC69,BRWD3,ESYT2,SKA3,NPHP4,UBE2E2,HNRNPAB,PLXNC1,TMEM184B,ST13,DNAJC24,ZNF107,KIF2C,SLC29A1,AGFG1,SIRT2,FKBP2,USP48,UBQLN2,SNRPD3,CUTC,EDC3,UBLCP1,ZNF804A,RAP1A,THADA,EIF4A3,AP3S2,ATG3,DPYSL2,PPP1R12C,AKR1B1,NDUFB9,JOSD1,RP2,TTC4,TECR,ARID4A,FGFR1OP2,TIMM50,TDP1,DPM1,FOPNL,SLC16A7,WDR82,SLC25A22,STK17B,DHX15,CHAF1A,GEMIN5,COPS6,SASS6,RPS26,PSMC1,SLC12A7,TBC1D12,TM9SF4,ZNF768,UFC1,MED13L,TIA1,MEF2A,EPHX2,PITHD1,RHBDD1,NFATC3,BANF1,BUD31,ZNF335,YBX1,KNTC1,ACAD8,UBE3C,ZNF189,ALDH9A1,KDELR1,TSTA3,CIC,OXR1,PSMA1,TMEM241,SEPT7,NAP1L1,NSMF,ODF2,EXOC4,KIAA1328,NUP62,PITPNA,NAA20,PTDSS1,MZT2B,PDSS2,C7orf26,TMEM106C,IMMT,ASH1L,CHERP,WDYHV1,PLAGL2,CHKB,IRF3,TWF2,PAIP1,ANKRD28,ANKLE1,FARSA,SAR1A,SCAMP4,APOOL,PDIA6,ACSL5,TOR1AIP2,AZI2,GFER,RAD54B,TMEM41A,DAP3,ZNF317,GADD45B,AKNA,REEP4,CBX4,MIF,KIF3B,GOLPH3L,SH2D3A,CASP6,TOR3A,SRGN,DBF4,MFSD10,SAC3D1,CTNNBL1,YIF1B,CLDND1,TTC17,SLC25A1,GINS1,PAQR6,CSNK1G2,TELO2,ADAM17,HMGN1,NASP,ASPM,PPP1R21,PRKAR1B,SYMPK,TARS,SNRPA,MAPK3,HSPA1B,HLA-B,ATAD2,PLAA,ZNF330,OSBPL8,KBTBD7,PREPL |
| 5.759e-09 | -18.97 | GSE1791_CTRL_VS_NEUROMEDINU_IN_T_CELL_LINE_6H_DN | MSigDB lists | GSE1791_CTRL_VS_NEUROMEDINU_IN_T_CELL_LINE_6H_DN | 180 | 58 | 17377 | 2626 |
HECA,DNAJC5,CDC40,ZCCHC9,TRIP12,ATG2B,XPO7,CUTC,CHD1,KIAA1147,PAIP2,WRNIP1,PRKD3,DNAAF2,ATP13A3,RAB4A,NUP107,TPST1,FBXW2,ACAD8,CNOT6L,LPCAT1,TMEM14C,NUP85,KDM3B,CYFIP1,PPP3CA,HMGN1,ZMYND11,DENND4C,PCGF6,ZBED5,CUL3,MTMR6,DCTD,PLEKHM3,CBFB,HAGH,H2AFV,EML4,DDX17,GNAS,OSBPL11,PCM1,CCDC14,VPS26B,OSBPL8,ITGB1,RWDD4,MEGF9,ADAM9,PKD2,NCOA1,ZNF45,MAPK1,FAM208A,CHPF2,HDAC2 |
| 5.759e-09 | -18.97 | GSE17721_0.5H_VS_8H_GARDIQUIMOD_BMDC_UP | MSigDB lists | GSE17721_0.5H_VS_8H_GARDIQUIMOD_BMDC_UP | 180 | 58 | 17377 | 2626 |
C9orf78,RECQL,NSMCE4A,EWSR1,MCM10,SYS1,KIAA0100,DNAJB2,GPR89A,VPS45,CERK,NDUFA4,THRAP3,NANS,SND1,MAPK14,ABHD14A,LMNA,FANCL,NUP210,TBC1D22A,ALDH18A1,MTX2,GM2A,KDELR1,TIMM50,NOL12,CSNK1G2,PTPN18,ZFP64,KIAA0930,PSMG1,CDC6,MEF2D,RPL27A,EIF3A,CLNS1A,SMAP2,TFEB,BRMS1,PAF1,UTP20,PON2,DAP3,HSPBP1,HINT1,ACYP1,QARS,FAM3C,NFIL3,CDCA5,COX8A,NCLN,KPNA2,ZMAT3,GPR89B,DDB1,VPS29 |
| 5.759e-09 | -18.97 | GSE2770_TGFB_AND_IL4_VS_IL12_TREATED_ACT_CD4_TCELL_6H_DN | MSigDB lists | GSE2770_TGFB_AND_IL4_VS_IL12_TREATED_ACT_CD4_TCELL_6H_DN | 180 | 58 | 17377 | 2626 |
RMND5A,MMACHC,UBE2E2,PTP4A3,AKT1S1,SND1,FOXO3,KTN1,NUP205,SAC3D1,NUDT19,ZNF428,CLIC4,GATC,KLF16,MTA1,FAM89B,PDS5B,SEPT11,BCAP29,TTC4,ECD,MRPL40,TALDO1,SPTSSA,TTLL12,GTF2H2,N4BP2,SAP30,RPP25,TDP1,PHF10,POLR2I,SIGMAR1,CPOX,USP10,CDC23,GFER,RDH11,UTP20,MID1IP1,CCDC6,PFDN4,PRDX3,EXOC4,CEBPG,PTAR1,TBPL1,IARS2,SIL1,KPNA2,ATF6,TRIM32,RUFY3,LRP8,HRAS,GCSH,ZNF511 |
| 5.796e-09 | -18.97 | TKT (transketolase) | protein interactions | 7086 | 169 | 58 | 17029 | 2761 |
MIF,POLA2,PDCD6IP,UFC1,TKT,ABHD14B,ATG2B,NANS,EIF2AK4,UBE2I,SPR,PCBP1,SDHA,SCYL2,TIGAR,PPME1,DUT,SRI,AKR1B1,TAGLN2,PTGES3,AHCYL1,TALDO1,CFL1,LYPLA2,GPX4,LDHB,WDR41,LAP3,WDR1,LDHA,CUL3,EZR,EXOSC9,GLO1,BRCA1,PITPNB,PLEC,PKM,VDAC1,MCM2,EML4,PRDX1,ISG15,GLOD4,GOLGA4,PDCD6,HINT1,H2AFX,TRIM32,FUS,GPI,DMWD,CDK2,IGBP1,TERF1,IFI16,SSSCA1 |
| 5.826e-09 | -18.96 | TRA2B (transformer 2 beta homolog) | protein interactions | 6434 | 91 | 38 | 17029 | 2761 |
UNK,DDX47,CYLD,EWSR1,IVNS1ABP,SF3B1,SRSF6,CUL1,LMNA,EIF4A3,BANF1,SRSF4,TNPO3,LUC7L2,SRSF10,SRPK2,YTHDC1,PRKDC,RNPS1,CUL3,ILF3,SREK1,BRCA1,SRSF5,DNAJA1,SEPT7,EIF4H,SF3A2,SRSF1,CAND1,CLK3,RBMX,YWHAZ,ZRANB2,SRSF3,SNRNP70,NKAPD1,HIPK3 |
| 5.836e-09 | -18.96 | GSE37532_VISCERAL_ADIPOSE_TISSUE_VS_LN_DERIVED_PPARG_KO_TCONV_CD4_TCELL_UP | MSigDB lists | GSE37532_VISCERAL_ADIPOSE_TISSUE_VS_LN_DERIVED_PPARG_KO_TCONV_CD4_TCELL_UP | 154 | 52 | 17377 | 2626 |
KARS,LYRM4,TMBIM4,MRPL39,RRM1,DHX8,IP6K2,NUP205,HDDC2,PRNP,CAPN2,ERH,PA2G4,PSMD2,RRN3,PSMA6,CDC42,ARPC5,MTMR4,ARL6IP1,PRC1,EI24,H2AFY,CTR9,SEPT11,PLCL2,STAT3,STRAP,ARL5A,FDFT1,RFC3,DHX29,MTA2,HNRNPF,POLR2D,SLBP,ODC1,BTBD1,ARF4,GINS4,DSN1,WDR11,PRDX3,ACOX1,PITPNA,MDH1,ANP32E,NAA20,NDE1,CDK2,HDAC2,SSRP1 |
| 5.853e-09 | -18.96 | GNF2_TDG | MSigDB lists | GNF2_TDG | 34 | 20 | 17377 | 2626 |
HNRNPAB,ZCCHC8,SUMO2,SNRPD3,DHX15,EIF3A,SRSF1,RPA1,PAPOLA,CBX3,HNRNPR,RBMX,U2SURP,SRI,TRA2B,NUP153,TARDBP,PTGES3,SRSF3,HNRNPM |
| 5.882e-09 | -18.95 | GO_CELLULAR_COMPONENT_DISASSEMBLY | MSigDB lists | GO_CELLULAR_COMPONENT_DISASSEMBLY | 494 | 123 | 17377 | 2626 |
CHMP2A,NUP188,TMEM203,MRPS15,ADAM10,ARID2,MRPL39,SMARCA4,KIF2C,CCNB1,STMN1,BECN1,BIRC2,MRPL19,BCAP31,MRPL50,NUP210,NEK6,ATG3,DNAAF2,KIF14,TXLNA,NUP107,MRPS27,MRPL34,NDUFB9,NUP153,CISD2,TARDBP,C8orf59,SMARCE1,DVL2,MRPL32,CFL1,SEH1L,CDC37,PLK3,PLK1,TIMP2,ATG9A,SNRPB,MRPL12,MRPL43,CRNKL1,FRAT2,LRP5,NUP155,CHMP2B,MRPS14,SUPT16H,MRPL2,DAP3,MRPL55,KIF18B,CHCHD1,AXIN1,EIF2D,MRPL27,ROCK1,DVL1,VPS4A,MRPL13,SMURF1,AAAS,PFKP,CAPN1,MRPL9,MRPL42,CLSPN,CASP6,MRPS2,RAE1,GSPT2,FLOT1,NUP54,MRPS26,KLC1,ATG2B,CSNK1A1,GFM2,NUP205,LMNA,ATG4A,MCTS1,RFWD3,KIF5B,CAPN2,CTSS,MEX3C,SLC1A4,RIMS3,BANF1,FBXO7,MRPL54,ANXA5,ATG13,MRPL48,MRPL40,MRPL21,MRPL11,NUP85,MICAL3,ZNF189,TMEM39A,MRPS10,MRPL16,ARID1A,MARK2,PI4K2A,FNTA,KPNA1,KIF18A,GOLGA2,COX8A,NUP62,HMGB2,MDH1,WIPI2,CHMP7,CCNB2,MRPL3,CDKN2A,SMARCD1 |
| 5.963e-09 | -18.94 | GSE10239_NAIVE_VS_MEMORY_CD8_TCELL_UP | MSigDB lists | GSE10239_NAIVE_VS_MEMORY_CD8_TCELL_UP | 189 | 60 | 17377 | 2626 |
RAB14,CYTIP,TRIM41,DNAJC5,TOMM20,MPHOSPH8,UBR2,TRMT6,LAMTOR3,GGA2,XPO7,TMEM165,TMEM161B,SF3B2,SLC25A36,LIN9,PRKD3,PIK3IP1,RNF19A,METTL9,NCOA2,CFL1,SMC4,CLCN3,EID1,C16orf72,GABPA,ZMYND11,ACSL3,LACTB,JTB,FBXO9,KDM1B,API5,POLG2,APPL1,MATR3,DHX15,RAB2B,CLNS1A,CBX3,TAF2,HSPB11,CDCA4,TTC13,LUC7L3,TULP3,KBTBD7,APPL2,OGT,QRSL1,NUP62,ZRANB2,SPCS3,NGLY1,SMAD4,HIPK3,GCSH,TMEM33,TMEM131 |
| 5.963e-09 | -18.94 | GSE20727_CTRL_VS_ROS_INHIBITOR_TREATED_DC_UP | MSigDB lists | GSE20727_CTRL_VS_ROS_INHIBITOR_TREATED_DC_UP | 189 | 60 | 17377 | 2626 |
MIF,GOLPH3L,SUCLG1,HJURP,MRPS15,PPP1R15B,FAM53C,ABCB10,SIRT2,SDF2L1,PSMD9,SSR1,FASTKD3,CD59,SHC1,IARS,BRPF3,NDUFB4,GOT2,SEC24C,YIF1B,CDC25B,ALDH18A1,ATF2,NDUFA3,N4BP2,MOSPD1,MLST8,SLC39A9,BAK1,MLEC,TIMP2,CSRP1,FAM118B,DENND1B,AACS,USP42,RDH10,TOP3A,KCTD20,MCL1,GALK2,AURKB,TMEM147,KRTCAP2,ICAM2,ERC1,ECH1,PSMC4,MAGED2,PLD3,TMEM41A,NEIL3,C4orf46,SIL1,KPNA2,MDH1,HEXA,CABLES1,CDKN2A |
| 6.211e-09 | -18.90 | DDX24 (DEAD-box helicase 24) | protein interactions | 57062 | 157 | 55 | 17029 | 2761 |
POLA2,BCCIP,NIFK,NOP2,RPLP2,KMT2E,RAE1,MECP2,RPL15,CSNK2A1,USP39,EBNA1BP2,BRIX1,UBE2I,RBM4,LMNA,RPL11,KRR1,TERF2IP,DDX56,MDM2,PIN1,NOC2L,RPF2,DDX31,CORO1A,FBL,ZC3H3,FTSJ3,TERF2,SPTAN1,NOL12,PPAN,DDX24,ZNF512,RPL6,GTPBP4,CUL3,RPL8,BRCA1,MAK16,TSR2,FADD,CAND1,NSA2,SYNCRIP,DGCR8,NIP7,RPS14,TBL3,RBPJ,TERF1,ZC3HAV1,IFI16,GPATCH4 |
| 6.250e-09 | -18.89 | DGCR8 (DGCR8, microprocessor complex subunit) | protein interactions | 54487 | 133 | 49 | 17029 | 2761 |
NIFK,EWSR1,NOP2,RPLP2,RAE1,MECP2,CDT1,DHX9,SMC6,CTCF,BRIX1,TTF1,APP,FANCI,ERH,DDX56,NVL,RPL17,CTR9,RPF2,DDX31,TFG,ZNF800,FTSJ3,ZNF189,SRPK2,MAPRE2,DDX24,KIF15,GTPBP4,CUL3,ILF3,PRKRA,KIF11,MAK16,CENPU,DDX17,NSA2,UPF1,ZNF777,HNRNPR,ZNF689,PRPF4,DDX5,FUS,MAPK1,ZC3HAV1,CDKN2A,CCDC137 |
| 6.301e-09 | -18.88 | PHB2 (prohibitin 2) | protein interactions | 11331 | 153 | 54 | 17029 | 2761 |
UNK,CYLD,RAB11B,SUZ12,XIAP,MEF2A,COX4I1,SIRT2,RAB11A,PDXDC1,NUP205,LMNA,SSR1,NDUFV1,NDUFA2,HUWE1,MCM5,ZNF746,NDUFS8,UPF2,CDC25B,CYC1,MRPL40,LMAN1,ATF2,MTX2,FGFR1OP2,TIMM50,LDHB,STAU1,RAB7A,RFXANK,ILF3,TUFM,VDAC2,DDX20,BRCA1,ADRB2,TOMM40,VDAC1,MCM2,GOSR1,STOML2,AKAP1,MRPL2,KPNA1,TFE3,XRCC3,KPNA2,NR2F2,ATP6V1C1,CDK2,HDAC2,TUBB |
| 6.325e-09 | -18.88 | CEP164 (centrosomal protein 164) | protein interactions | 22897 | 84 | 36 | 17029 | 2761 |
NPHP4,DDX47,TOP2B,NKRF,EBNA1BP2,MAPK14,NUP205,DDX56,NOL11,NVL,ZNF326,PDS5B,RPF2,TRA2B,MTPN,SRSF10,DDX24,AATF,NSUN2,PEF1,RFC2,USP36,ECH1,SUPT16H,DDX23,CDC16,PCM1,C1orf131,TBL3,BTF3,YY1,IDH3B,PDCD11,NMD3,CAPN1,SSRP1 |
| 6.364e-09 | -18.87 | RPL15 (ribosomal protein L15) | protein interactions | 6138 | 186 | 62 | 17029 | 2761 |
RPS15,NIFK,RPS2,CYLD,NOP2,RPLP2,MECP2,DHX8,CUL1,PABPC4,RPL11,RPL23A,FAM192A,RPA2,PA2G4,MDM2,EIF2S2,IARS,EIF4A3,RPL17,HUWE1,RBM34,RPL19,TARDBP,FBL,ZC3H3,PABPC1,LUC7L2,EEF1D,STAU1,RPL35,DDX24,RPS10,RPL6,TUFM,RPL38,CUL3,ILF3,RPL8,RPS24,BRCA1,MCM2,RPL27A,SLC25A5,RPS9,RPSA,CLNS1A,RPA1,RPL36,CAND1,NAP1L1,RPL32,RPS27A,RPS14,QARS,MYO18A,RPLP1,ACTB,COPS6,ARRB2,RPS26,GPATCH4 |
| 6.409e-09 | -18.87 | GO_PHOSPHATE_CONTAINING_COMPOUND_METABOLIC_PROCESS | MSigDB lists | GO_PHOSPHATE_CONTAINING_COMPOUND_METABOLIC_PROCESS | 1870 | 369 | 17377 | 2626 |
FGFR1OP,PPCS,NDUFB6,ADAM10,PIGQ,HEXB,AGPAT1,CUL1,CCNB1,SLC20A1,RBM4,EEF2K,CDK5,CALM2,PSMD1,NEK6,UPRT,FNIP2,MAST2,CDC25B,SLC26A2,KCNAB2,PGAP2,PLK3,NRAS,AKT2,PBK,AURKB,STOML2,MAP3K4,MKNK1,SMAD2,RPS27A,PSMD8,AXIN1,LIMK1,PRDX5,PTPN7,DHTKD1,MLYCD,COX5A,UQCRH,PTPDC1,RNASEL,SMAD1,PFKP,NDUFV2,COX5B,GMFG,CLSPN,PRKAA1,TRIO,CERK,RRM1,NDUFA4,CYCS,EIF2AK4,PSMD9,NDUFS7,NDUFS4,PDXP,INPP5A,ATIC,PPP4R1,MSH2,DAPK1,PIGG,ATP6V0A2,PCYT2,CYC1,PIKFYVE,LPCAT1,PPA1,PHKG2,MORC3,FDFT1,PIGT,RB1CC1,MAPKAPK3,PGS1,PIP4K2C,DCTD,MPG,MAP2K2,PSMB3,PI4K2A,ADSS,PTPRF,CAT,DUSP3,CSK,DCK,CSNK1G1,PPP3R1,LPCAT4,MDH1,SAMD8,GPI,SMPD4,MAP3K5,CDK2,NRBP1,NUDT3,KARS,TP53RK,RPS6KA1,RAF1,OLA1,ADPGK,SLC35B2,PRKACA,LCLAT1,APP,CPNE3,EPM2A,FLAD1,CRKL,PRKD3,SHC1,MTMR4,DUT,LPIN2,ADCY9,TALDO1,GPD1L,RPRD1B,CDK12,ILKAP,GPX4,ADCY7,CPNE1,ULK3,TAOK1,MAP4K4,CUL3,ATP6V0A1,PFKFB3,GALK2,NDUFA7,PKMYT1,PSMB9,TAZ,ERC1,TRIM28,PPP2CA,JAK1,HINT1,ACYP1,HIPK2,PPA2,MBOAT1,PDXK,PPP5C,EYA2,CSNK1D,PRPF4B,GALK1,NDUFS1,MECP2,CCM2,TKT,BRAP,AGPAT3,ABHD14B,IP6K2,PMVK,NEIL2,PIP5K1C,PPP1R3B,CCNK,ERH,PSMD2,NDUFA2,PTEN,NDUFB4,PTPN11,CREB1,MAP3K14,GTF2H2,NDUFA3,IMPA2,LDHB,SPTAN1,PDPK1,PPP3CA,TK1,GUK1,NEK7,ILF3,LDHA,TBRG4,ADSL,PDE3B,MARK2,GPS2,MAPK6,DBI,PML,DUSP11,NDUFS5,CCNC,PIGM,COX15,NF1,UQCR10,HMGXB3,PPP1R15B,SNX15,PTP4A3,CSNK2A1,CDIPT,MAPK14,UBLCP1,MBD4,ABL2,NT5DC1,IMPAD1,SLC44A1,PIK3R2,HADHB,PPCDC,NDUFB9,OGG1,FGFR1OP2,TIMM50,SRPK2,CDC37,PTPRK,PLK1,PTPN18,DPM1,RBX1,NCK1,TLK1,GMFB,RRM2,IL12RB1,PRKRA,PRPSAP1,STK17B,ABHD5,AGPAT2,PPM1G,BAZ1B,CAB39,STK11,ROCK1,CHEK2,CLN3,CHPT1,NUDT11,PSMC1,SEPHS2,PIGN,PPP1R12A,LAMTOR3,MEF2A,ADCK5,CDK13,COX4I1,PPP3CB,EPHX2,CHKA,NUS1,BCL2,MDFIC,ALDH18A1,MAML1,N4BP2,HDHD2,CSNK1G3,NTPCR,NUDT4,PSMA1,MAP4K3,EIF2AK1,KRAS,EIF2A,STYXL1,DAPK3,MASTL,PSMC4,COX7A2L,PRPS2,TBPL1,FN3KRP,NANP,PTDSS1,PRKAB1,NDUFA5,SUCLG1,UGP2,MDH2,UCK2,UCK1,CHKB,ATP6V1B2,LYN,GGPS1,DUSP22,VAV1,PDK2,PSMA6,PPP6C,MINPP1,F2R,SCYL3,ABI1,CTDSP2,PSMA8,PSMB7,MTMR6,OGDH,NDUFB1,TOLLIP,PDHX,ATP1A1,TAB2,CLK3,STK38,FASTK,PSMD3,NDUFA11,MAPK1,CTDP1,NADSYN1,CDS2,SH2D3A,EYA1,GNE,SCYL1,ARF1,CDK11B,CSNK1A1,SCYL2,PIP4K2A,PTPN2,FASTKD3,FGFR3,GART,NDUFV1,NDUFS8,STAT3,CAMK2G,TGFB1,AMPD2,CSNK1G2,ACP2,RPRD1A,PRKDC,PRKAR1B,PNPLA8,MEN1,CDK11A,HSPA1B,MAPK3,MTMR3,NEK1,PLAA,BIRC5,COX8A,KBTBD7,IMPDH1,FAM126A,IDH3B,RPS6KC1,PGAM1,HIPK3,HRAS |
| 6.578e-09 | -18.84 | REACTOME_HIV_INFECTION | MSigDB lists | REACTOME_HIV_INFECTION | 185 | 59 | 17377 | 2626 |
CTDP1,NUP188,POLR2K,RAE1,RAC1,NUP54,ARF1,AP1B1,PSMD9,NUP205,HLA-A,GTF2F1,PSMD2,PSMD1,NUP210,PSMA6,BANF1,NUP107,AP1M1,AP2B1,NUP153,TCEA1,GTF2H2,NUP85,SEH1L,POLR2I,POLR2L,POLR2G,PSMA8,RBX1,PSMB7,POLR2D,PSMA1,NUP155,RANGAP1,PACS1,PSMB9,SLC25A5,POLR2A,PSMB3,NMT2,PSMC4,XRCC5,SUPT16H,KPNA1,POLR2J,ELMO1,RPS27A,PSMD8,PSMD3,AP1S1,NUP62,TAF12,XRCC4,TAF6,PSMC1,AP2S1,AAAS,SSRP1 |
| 6.578e-09 | -18.84 | GSE17721_POLYIC_VS_PAM3CSK4_6H_BMDC_DN | MSigDB lists | GSE17721_POLYIC_VS_PAM3CSK4_6H_BMDC_DN | 185 | 59 | 17377 | 2626 |
RMND5A,CTDP1,TMED7,DNAJC2,PIGM,TP53RK,GMFG,TMEM203,GNPDA1,POLR2K,KLHL21,DNAJB2,IRF3,TMEM165,RAB11A,RRP36,FERMT3,SEC11A,LYAR,NAPG,SHC1,ADCY9,BTF3L4,PTPN11,RNF5,USP34,NOL12,SLC39A9,EIF3L,LARS,MAPRE2,PPP1R18,TEX10,MKI67,PSMA1,CDC6,ARHGDIB,BRCA1,MEF2D,RHOT1,CYFIP2,TXNL4A,EIF4H,TSR2,CCT8,ABHD5,UTP20,TMEM184C,SEC31A,HSPA4,ATP1A1,FNTA,STT3A,BIRC5,NDUFA11,ACLY,TBPL1,KLHDC4,NMD3 |
| 6.578e-09 | -18.84 | GSE9988_ANTI_TREM1_AND_LPS_VS_CTRL_TREATED_MONOCYTES_DN | MSigDB lists | GSE9988_ANTI_TREM1_AND_LPS_VS_CTRL_TREATED_MONOCYTES_DN | 185 | 59 | 17377 | 2626 |
RHOG,KIF3B,CYTIP,PIGM,HECA,KDM4A,PHF23,RPS6KA1,CCM2,KLF13,CTCF,TWF2,MAPK14,GNB2,GIT2,PIP5K1C,SF3B2,PHC2,RAB8A,KDM2A,AP1M1,FAM89B,GLTP,CORO1A,NAP1L4,GLE1,MAP3K14,ZNF710,CTDSP2,KDM3B,ORAI2,STAU1,TRIM8,FOXK1,TACC1,FRAT2,WDR82,MAP7D1,ARID1A,USP22,PTTG1IP,BUD13,DDX23,MYO1F,DDX17,ZNF282,HHEX,FBXO21,GNA12,OSBPL11,CSK,RNF38,ZNF436,ZDHHC7,WIPI2,YY1,ARRB2,PURA,PRPF4B |
| 6.578e-09 | -18.84 | GSE22601_DOUBLE_POSITIVE_VS_CD4_SINGLE_POSITIVE_THYMOCYTE_DN | MSigDB lists | GSE22601_DOUBLE_POSITIVE_VS_CD4_SINGLE_POSITIVE_THYMOCYTE_DN | 185 | 59 | 17377 | 2626 |
GLT8D1,MIF4GD,TXN,ST13,HJURP,POC1A,RRM1,TPX2,PTP4A3,RACGAP1,TAF6L,KIF2C,NCAPG,NUP205,MBD4,RFWD3,DECR1,PCNA,CENPJ,UCHL5,PDS5B,ARL6IP1,GTSE1,GEMIN6,CLDND1,CLN6,PCBP2,MSH6,TACC3,SMC4,TDP1,CSRP1,RNASEH2C,CDC123,DHX29,MRS2,ITM2A,CKAP2L,BRCA1,PRKRA,MCM2,KIF11,TRIM28,ECH1,GLOD4,NAP1L1,IDE,ATAD2,RBL1,TFDP1,CDCA7L,H2AFX,ANP32E,TCOF1,NDE1,WDR62,PITRM1,CD81,SSRP1 |
| 6.578e-09 | -18.84 | GSE13484_UNSTIM_VS_3H_YF17D_VACCINE_STIM_PBMC_UP | MSigDB lists | GSE13484_UNSTIM_VS_3H_YF17D_VACCINE_STIM_PBMC_UP | 185 | 59 | 17377 | 2626 |
SEPHS2,WASF2,TCF12,CAST,TCF3,PCSK7,CDK13,MAN2B1,UBE4A,FAM136A,SNRPD3,DCUN1D4,EPHX2,METTL3,RSAD1,CNOT3,SSR1,PCYOX1L,SLC25A36,ATG4A,C12orf10,SEC11A,SHC1,THADA,TBC1D22A,UBE3B,PPP6R1,HTRA2,ABCC5,LDHB,NCK1,LRBA,PIP4K2C,PTTG1IP,MATR3,AKAP1,ZMYM3,DDX23,CBX3,AMZ2,MAN2A2,PFDN5,FBXO41,PRDX3,LIMK1,AXIN1,NAGLU,APPL2,MEGF9,USP20,CABIN1,ACADM,CENPT,GPI,NDE1,TMEM14A,PDSS2,MRPL3,DDX42 |
| 6.578e-09 | -18.84 | GSE9988_LOW_LPS_VS_CTRL_TREATED_MONOCYTE_DN | MSigDB lists | GSE9988_LOW_LPS_VS_CTRL_TREATED_MONOCYTE_DN | 185 | 59 | 17377 | 2626 |
WASF2,PIGM,HECA,DNAJC5,PHF23,TSC22D3,KLF13,CTCF,PCBP1,RCOR3,SYNRG,GIT2,MEAF6,PIP5K1C,SF3B2,PHC2,RAB8A,UBE2Q2,SMC3,PPP1R8,MBD2,FBXO7,FAM89B,BRI3,ZNF226,GLE1,NAP1L4,MAP3K14,CTDSP2,KDM3B,ORAI2,STAU1,AGGF1,FOXK1,ATG9A,TACC1,FRAT2,WDR82,RTF1,MAP7D1,USP22,KDM3A,DDX17,TFEB,DDX23,HHEX,ZNF282,OSBPL11,CSK,RNF38,CAB39,ZDHHC7,CENPBD1,WIPI2,YY1,ZNF45,NRBP1,DCAF5,PURA |
| 6.688e-09 | -18.82 | MMGT1 (membrane magnesium transporter 1) | protein interactions | 93380 | 110 | 43 | 17029 | 2761 |
NDUFV2,IMMT,CORO7,GOLIM4,NDUFS1,PHB2,SF3B1,TMEM109,FLOT1,COX4I1,UBQLN2,HDGFL2,KTN1,APP,RBM17,HNRNPA2B1,GOLM1,DNAJC8,NDUFA2,NSRP1,TTC9C,MTX2,CCAR1,BRD4,TRIR,TMEM216,VDAC2,NDUFA7,VDAC1,ANLN,CHCHD6,DHX15,STOML2,CHCHD3,DERL1,GALNT2,BRWD1,MFAP1,CORO1C,MPV17,IMPDH1,ZMAT3,PARD3 |
| 6.735e-09 | -18.82 | GO_VIRAL_LIFE_CYCLE | MSigDB lists | GO_VIRAL_LIFE_CYCLE | 277 | 79 | 17377 | 2626 |
CHMP2A,PDCD6IP,NUP188,THOC1,RPLP2,EIF3D,TAP1,MON1B,PCBP1,RPL11,RPL23A,USF1,NUP210,ZNF639,SIVA1,NUP107,NUP153,TAP2,PCBP2,SEH1L,RPL29,RPL35,RAB7A,SELPLG,RPL38,NUP155,RAB1A,CHMP2B,EIF3G,RPS9,RPSA,EIF3A,RPL37,IDE,CHMP4A,RPS27A,RPS14,ITGB1,RPLP1,KPNA2,CHMP4B,SCARB1,VPS4A,FAU,RPS26,AAAS,RPS15,RPS2,RAE1,NUP54,RPL15,EIF2AK4,ITGB5,TFRC,XPR1,NUP205,WWP2,RPL17,RPL19,LRSAM1,NUP85,EIF3L,RPL8,RPL6,RPS10,RPS24,RPL27A,NMT2,HSPA1B,RPL36,DERL1,SCARB2,KPNA4,KPNA1,RPL32,NUP62,CHMP7,USF2,CD81 |
| 6.799e-09 | -18.81 | GO_REGULATION_OF_CELL_CYCLE_ARREST | MSigDB lists | GO_REGULATION_OF_CELL_CYCLE_ARREST | 101 | 39 | 17377 | 2626 |
MIF,FOXM1,CAST,CCNB1,PRKACA,CRLF3,CNOT3,CDK5,TFAP4,CCNK,MDM2,PCNA,CENPJ,GTSE1,CDKN1B,CNOT6L,CARM1,TGFB1,PLK3,HMGN5,AKT2,BTG2,BRCA1,SOX4,RBM38,RPS27A,E2F4,TFDP1,UHRF2,E2F1,PML,PKD2,ZNF268,CNOT6,CHEK2,TFDP2,CDK2,SLC25A33,CDKN2A |
| 6.886e-09 | -18.79 | catabolic process | biological process | GO:0009056 | 1996 | 392 | 17256 | 2622 |
PDCD6IP,HEXB,CUL1,GLUD1,NHLRC3,GYG1,CCNB1,UBE2I,OAT,PARK7,FBXO22,PABPC4,RPL23A,CDK5,PSMD1,RAD23B,MECR,AP2B1,CISD2,PCBP2,USP34,ATG9A,TOPORS,SUPT20H,USP22,AURKB,AMDHD2,CCNF,PLEKHF2,RPS27A,PSMD8,RPS14,PTER,AXIN1,PRDX5,ATE1,MLYCD,VIPAS39,DHTKD1,KLHL42,SMG9,FBXL3,ARRB2,LONP2,PFKP,MUT,DHPS,PHF23,GSPT2,ADO,PRKAA1,RAB23,TATDN3,KCTD17,MAN2B1,ZNRF3,PSMD9,PARN,PSEN1,METTL3,VPS25,CNOT3,NPLOC4,ATG4A,GNS,RNF121,PDXP,EXOSC7,INPP5A,ZNRF2,FBXO7,BDH1,FBXL7,PABPC1,PHKG2,CPQ,RB1CC1,MAN1B1,RPS10,USP10,RPS24,EXOSC9,PKM,TOMM40,PATL1,PSMB3,DERL1,CAT,KPNA1,DCAF11,USP32,CNOT6,SMPD4,GPI,WIPI2,HEXA,RNF139,SNX14,NUDT3,ATXN3,TRERF1,UBR2,PTTG1,VTI1A,ADPGK,STAM,ABHD16A,NUDT19,DECR1,SIAH1,MTA1,UCHL5,DUT,LPIN2,SOCS6,NSFL1C,ANAPC7,TTC3,RNASEH2A,CLN6,GPD1L,ENPP4,ULK3,SEC61B,RPL38,POLR2D,RNPS1,CUL3,RAB1A,CDC23,PSMB9,PPP2CA,ANKZF1,ALDH3B1,CDC16,CHMP4A,HINT1,RAB24,LSM6,NT5C3B,RNF38,RPLP1,SEL1L,TRIM32,USP13,GALK1,RPS2,MANBA,ATG2B,SDF2L1,UBE4A,NEIL2,TUT4,WWP2,CAPN2,PSMD2,RPL17,PTEN,CRAT,PPP1R8,FUT8,DCP1A,GTSE1,LTN1,RPL19,UPF2,CNOT6L,FBXL19,PACS2,IMPA2,LYPLA2,TNFAIP3,GALC,RNASEH2C,TRIR,USP42,RPL8,LDHA,FBXO9,ANAPC2,PDE3B,RPL27A,MARK2,ECH1,PRDX1,SH3GLB1,PLD3,FBXO21,SGSH,KEAP1,HGS,RPL32,PRDX3,TATDN2,ACOX1,PML,KHSRP,PPP1R11,DDX5,HMGB2,WDR91,YWHAH,WDR45B,ANAPC4,FAF1,DDB1,SNAPIN,ADA2,AGRN,GNPDA1,RBM8A,MCCC1,CSNK2A1,UBE2Z,SND1,SIRT2,UBQLN2,USP48,MAP1LC3B,BECN1,BIRC2,RNF103,EDC3,BCAT2,PCYOX1L,MBD4,TET3,RAB8A,GOT2,EIF4A3,RAB35,ATG3,METTL14,SLC44A1,HADHB,OGG1,DRAM2,WDR41,PLK1,EXOSC6,RBX1,LRP5,USP21,OPTN,RPL37,TBC1D17,NAGLU,ARRDC1,STK11,CHEK2,CLU,VPS4A,CLN3,NUDT11,NGLY1,RPS26,PSMC1,CAPN1,UBE2D3,RMND5A,RPS15,TMUB1,UBXN1,SDC2,RPL15,PM20D2,THRAP3,CNOT11,EPHX2,RHBDD1,PRPF18,DTL,TIGAR,VMP1,EI24,SLC27A4,AHCY,ACAD8,ZRANB1,LRSAM1,ABHD2,ERLIN1,NUDT4,RPL6,GBA,PSMA1,UBE4B,SYVN1,ARMC8,RMC1,ISG15,RPL36,PSMC4,CDC27,KLHL15,SIAH2,CTSA,DNPH1,ECPAS,USP7,CHMP2A,PRKAB1,TOMM20,CYLD,RPLP2,DYNLL1,PAIP1,RPL11,RAD23A,USP5,CSDE1,UBXN2A,PSMA6,MDM2,KIF14,EXOSC1,GM2A,SPSB3,HTRA2,RLIM,CHP1,PRPF19,SNX25,RPL29,UBQLN4,RPL35,POLR2G,PPT1,PSMA8,HPDL,RAB7A,PSMB7,OGDH,VDAC1,CHMP2B,EDEM2,TOLLIP,RPS9,USP36,BTBD1,RPSA,PON2,DNAJC10,IDE,UBXN2B,TOMM6,PSMD3,ARNTL,CHMP4B,SCARB1,USP11,SMURF1,LTA4H,AP2S1,CHID1,TRIP12,DAP,CHAC2,CSNK1A1,DNAJB9,CTSS,KLHL20,PELO,ATG13,ABCD1,RNF5,TGFB1,SAMD4B,RFFL,WDR81,PNPLA8,HAGH,NEU1,MFN2,TFEB,HSPA1B,CNOT9,MTMR3,CTSL,UPF1,PLAA,SNAP29,CTBS,ACAT1,USP20,ACADM,TATDN1,UBE2C,PGAM1,SAT2,GCSH,IFI16 |
| 6.912e-09 | -18.79 | Infectious disease | REACTOME pathways | R-HSA-5663205 | 388 | 108 | 10287 | 1696 |
CHMP2A,NDC1,PDCD6IP,NUP188,RPLP2,RAC1,AP1B1,STAM,RPL11,RPL23A,CALM2,PSMD1,PSMA6,NUP210,GRSF1,NUP107,AP1M1,AP2B1,NUP153,TCEA1,SEH1L,RPL29,RPL35,POLR2L,POLR2G,PSMA8,RBX1,PSMB7,ELOA,RPL38,POLR2D,NUP155,CHMP2B,PSMB9,SLC25A5,RPS9,RPSA,SUPT16H,TAF2,RPL37,CHMP4A,RPS27A,PSMD8,PSMD3,RPS14,RPLP1,AP1S1,KPNA2,CHMP4B,VPS4A,FAU,XRCC4,PSMC1,RPS26,AP2S1,AAAS,SSRP1,RPS15,CTDP1,RPS2,POLR2K,RAE1,NUP54,CBLL1,RPL15,ARF1,PSMD9,HLA-A,NUP205,GTF2F1,CCNK,PSMD2,RPL17,BANF1,RPL19,CPSF4,GTF2H2,RPL22L1,NUP85,TGFB1,POLR2I,RPL8,RPS10,RPL6,PSMA1,RPS24,RANGAP1,PACS1,RPL27A,MAP2K2,ISG15,POLR2A,PSMB3,NMT2,PSMC4,RPL36,XRCC5,HGS,KPNA4,KPNA1,POLR2J,RPL32,ELMO1,NUP62,TAF12,CHMP7,TAF6,NUP58 |
| 7.242e-09 | -18.74 | GSE37301_LYMPHOID_PRIMED_MPP_VS_GRAN_MONO_PROGENITOR_DN | MSigDB lists | GSE37301_LYMPHOID_PRIMED_MPP_VS_GRAN_MONO_PROGENITOR_DN | 181 | 58 | 17377 | 2626 |
SEPHS2,PIGN,FEZ2,NDUFS1,CKLF,TMEM41B,ABCC10,SUMO2,FLOT1,CTCF,PXMP2,NOTCH2,MAN2B1,FKBP2,UBE2I,AP3S1,ZNF518A,RMI1,WRB,WWP2,INPP5A,ARPC5,SH3BP1,LPIN2,MRPL34,FAM89B,PIGG,EFCAB11,KIFAP3,GNAI2,MYBL1,DNMT1,VOPP1,CSNK1G2,ZFP64,SEPT9,TACC1,PPT1,KAT7,PARP4,E2F3,AMDHD2,LY6E,ZDHHC3,USP21,CHAF1A,ANKZF1,TRIM26,HSPB11,PPP2R5A,TMEM168,HINT1,E2F1,USP20,MRFAP1L1,ROCK1,ZMIZ1,NXT2 |
| 7.242e-09 | -18.74 | GSE23695_CD57_POS_VS_NEG_NK_CELL_UP | MSigDB lists | GSE23695_CD57_POS_VS_NEG_NK_CELL_UP | 181 | 58 | 17377 | 2626 |
MBD1,DNAJC2,ANKRD27,ZFP91,CHD1L,HNRNPUL2,CERK,CTCF,PLXNA1,SLC12A9,SYNRG,PARN,QSOX2,PIP5K1C,SRXN1,ZBTB45,ZNF639,PPIL2,TXLNA,AP1M1,BRD7,RPF2,CISD2,POLR1B,MRPL40,AQR,EBAG9,B3GALT6,SRP72,TELO2,MKI67,PFKFB3,CDCA2,PBRM1,MTX1,GAR1,ANKRD46,AKAP1,PPP2CA,KIF2A,ZNF862,ZNF282,HHEX,INF2,WDR11,FAM3C,FAM122A,CANT1,ZRANB2,TRIM32,BEND3,RBPJ,CD81,TAF6,TSEN15,TUBB,HDAC2,SSSCA1 |
| 7.359e-09 | -18.73 | SRSF11 (serine and arginine rich splicing factor 11) | protein interactions | 9295 | 88 | 37 | 17029 | 2761 |
ZNF207,SART1,EWSR1,PNISR,CSNK2A1,USP39,JMJD6,ARGLU1,THRAP3,ETS1,SF3B2,MDM2,GATC,PIN1,TANK,MSH2,LUC7L2,TERF2,SRPK2,PRPF19,SF3B6,SMU1,RNPS1,CUL3,SREK1,LNX2,SHCBP1,LUC7L,SNRPA,DHX15,CAND1,SRSF1,RBM25,DDOST,ZRANB2,SRSF3,SNRNP70 |
| 7.455e-09 | -18.71 | LY_AGING_MIDDLE_DN | MSigDB lists | LY_AGING_MIDDLE_DN | 16 | 13 | 17377 | 2626 |
PLK1,CCNA2,FOXM1,CENPF,H2AFX,MYBL2,KIF23,KIF2C,CCNB1,CCNF,KIF11,UBE2C,HMGN2 |
| 7.457e-09 | -18.71 | WAKABAYASHI_ADIPOGENESIS_PPARG_RXRA_BOUND_8D | MSigDB lists | WAKABAYASHI_ADIPOGENESIS_PPARG_RXRA_BOUND_8D | 814 | 183 | 17377 | 2626 |
PPCS,NUP188,LUZP1,PRKCSH,PPP1R15B,AGPAT1,SNRPD3,ELMOD2,BCAT2,EDC3,PRNP,NEK6,SIVA1,SRSF4,TXLNA,MOB1A,TIPARP,PCBP2,DRAM2,MLST8,BAZ2A,GABPA,TMEM216,HNRNPF,AMDHD2,ESYT1,UTP3,PRKRA,PLEKHF2,ARF4,EIF4ENIF1,MID1IP1,AGPAT2,BAZ1B,ST3GAL2,ATP6V0C,ZSWIM3,CLN3,CHPT1,LONP2,HIVEP3,RMND5A,LIME1,HJURP,SCOC,ZNF768,CERK,TIA1,ASAH1,ADCK5,CDK13,PXMP2,EPHX2,LMNA,NDUFS4,RPN1,RNFT1,LRRC8D,ZNF326,TNPO3,GNAI2,NUP85,PREB,CYTH1,IFRD1,ETV3,ACSL3,UBE4B,TOMM40,PTTG1IP,ARMC8,GOSR1,ZDHHC3,CYB5A,BBS12,ANKRD46,DERL1,SCARB2,CDC27,TMEM168,SAMD8,NDUFA5,IMMT,GGNBP2,GNPNAT1,TRAF7,SUCLG1,CAST,KIAA0232,SLC39A13,ZFYVE21,UCK1,TBC1D13,SNN,HCFC1R1,MXD1,USP5,ARL6IP6,FLAD1,MDM2,CCDC50,SHC1,CS,PARL,TALDO1,METTL9,ABI1,ZNF770,CPNE1,MND1,FAM172A,MKLN1,IDH3A,KAT7,SLC26A6,GLO1,KDM1B,GFER,PPP2CA,CHCHD3,PEX5,STAT6,H2AFX,STAT1,LMBR1,RBMS1,XRCC3,SLC25A39,USP53,CSNK1D,PRPF4B,TMEM33,OTUD5,UNK,RPS2,DAP,CDCA3,TRAK1,LETMD1,CHIC2,AKT1S1,AP3S1,REEP5,TMCC3,GTPBP3,CAPN2,CTNNBL1,SEC24C,TANK,SLC35B4,BTF3L4,SLC38A10,NDUFS8,LDLRAD3,RNF5,LDHB,GINS1,PDPK1,ZDHHC18,CSNK1G2,PPP1R9B,DCAF6,FAM49B,NET1,PSPC1,WDR18,PPWD1,PNPLA8,ECH1,FADD,SH3GLB1,POLE,SLC38A7,ACOX1,FAM3C,IMPDH1,MBD6,ACADM,WDR62,NR2F2,PLOD3,GCSH,TMEM131 |
| 7.774e-09 | -18.67 | USP7 (ubiquitin specific peptidase 7) | protein interactions | 7874 | 328 | 94 | 17029 | 2761 |
ZNF207,USP7,PDCD6IP,DNMT3A,KMT2E,SUZ12,SUMO2,MYH9,BIRC2,MEAF6,MBD4,CRKL,MDM2,BABAM2,ABRAXAS2,ETV6,PPP6C,CRY2,MCMBP,DNMT1,HTRA2,RNF169,CDC37,RYBP,TRIM8,BIRC3,PCGF6,CUL3,RNPS1,HNRNPF,ATXN1,BRCA1,PITPNB,OGFR,USP21,PPP2CA,RAD18,CLK3,TULP3,AXIN1,PPM1G,UHRF2,OGT,FKBP5,COPS6,USP11,TRAF5,XRCC4,UBE2D3,HSPH1,EWSR1,PKP4,TRIP12,CLSPN,ZCCHC8,RAE1,BABAM1,DHX9,KIF23,KLC1,MYNN,FOXO3,LMNA,WWP2,RPA2,RB1,MEX3C,PTEN,HUWE1,MCM5,TANK,FOXN2,TXNL1,WDR1,RFFL,SYVN1,PKM,PCGF1,MACF1,SH3GLB1,RPA1,AKAP1,MAGED2,KPNA1,ATP6V1D,CCDC6,PML,RUVBL2,RBPJ,PPP6R3,CDK2,TSEN15,IFI16,VPS29 |
| 7.787e-09 | -18.67 | ribosomal subunit | cellular component | GO:0044391 | 189 | 59 | 18223 | 2701 |
RPS15,MRPL9,RPS2,RPLP2,MRPL42,MRPS2,MRPS15,MRPL39,MRPS26,RPL15,MRPL19,MCTS1,RPL23A,RPL11,MRPL50,RPL17,MRPS27,MRPL34,MRPL54,RPL19,RBM3,MRPL40,MRPL48,MRPL21,MRPL11,RPL22L1,NSUN4,MRPL32,RPL29,RPL35,MRPL43,RPL6,MRPL12,RPL8,RPL38,RPS10,MRPS10,RPS24,MRPL16,EIF2A,RPL27A,MRPS14,RPS9,RPSA,RPL36,RPL37,GEMIN5,MRPL2,DAP3,RPL32,MRPL55,RPS27A,RPS14,MRPL27,EIF2D,RPLP1,MRPL13,RPS26,MRPL3 |
| 7.957e-09 | -18.65 | GSE6674_ANTI_IGM_VS_PL2_3_STIM_BCELL_UP | MSigDB lists | GSE6674_ANTI_IGM_VS_PL2_3_STIM_BCELL_UP | 177 | 57 | 17377 | 2626 |
MRPL9,CYLD,GOLPH3L,POC1A,UROD,HEXB,CDCA3,CDCA8,KIF2C,MXD4,RGS2,IFT27,COMMD8,RPAIN,MAT2B,OIP5,CDKN2C,USF1,PPIL2,ZNF260,TTC9C,FAM89B,INTS12,ANAPC7,PIK3IP1,TERF2,DCTN1,DCAF6,CSRP1,KIAA0040,GLO1,PTTG1IP,PRMT2,ARSK,PDE3B,TTC33,RAB2B,GINS4,SUGP1,SCARB2,DSN1,STK38,NSMCE2,OAZ2,MRPL27,FAM3C,MPV17,ZNF436,SSNA1,TFDP2,C11orf1,NGLY1,MZT2B,TOB1,ZC3HAV1,PDCD4,ESYT2 |
| 7.972e-09 | -18.65 | AURKA (aurora kinase A) | protein interactions | 6790 | 319 | 92 | 17029 | 2761 |
RPLP2,PRKCSH,PTTG1,TPX2,KLHL18,CSNK2A1,NUF2,KIF2C,BCL2L1,CNTROB,UBE2I,PRKACA,SYNRG,APP,RPL11,HNRNPA2B1,MDM2,PSMA6,IARS,MTMR4,PPP6C,MECR,TTC4,CDC25B,TACC3,ELOF1,CDC37,SRPK2,PLK3,PLK1,PSRC1,MAPRE2,AATF,VHL,TLK1,RPL38,PSMB7,CUL3,HNRNPF,EZR,AURKB,BRCA1,SMC2,SUPT20H,MBD3,USP21,TRIM28,UBTF,RPS14,CEP55,FUS,HDAC2,TUBB,SSRP1,NCOR2,MAPRE1,SEC61G,SCYL1,DHX9,RAPGEF6,HEATR5B,SNX18,CTPS1,YBX1,PDLIM2,FTL,TACC1,RPS10,ILF3,PSMA1,MRPL16,BORA,MATR3,TARS,CBX3,CNOT9,MTMR3,EPRS,PDCD6,BIRC5,MAPK6,LRPPRC,PML,DDX5,YY1,PPP6R3,PPP6R2,WDR62,DDB1,IFI16,CDKN2A,SSSCA1 |
| 8.056e-09 | -18.64 | Oxidative phosphorylation | KEGG pathways | hsa00190 | 120 | 45 | 7161 | 1149 |
NDUFA5,COX15,COX5B,NDUFV2,NDUFS1,NDUFB6,UQCR10,COX4I1,NDUFA4,ATP5F1B,ATP6V1B2,ATP5PF,SDHA,NDUFS7,NDUFS4,ATP6V0B,NDUFV1,NDUFA2,NDUFB4,ATP6V0A2,NDUFS8,NDUFB9,CYC1,NDUFA3,ATP6V0D1,PPA1,ATP6V1G1,ATP6V0A1,NDUFA7,ATP5MF,NDUFB1,SDHB,ATP6V1D,ATP5MC3,NDUFA11,COX7A2L,COX8A,PPA2,COX5A,UQCRH,ATP6V0C,NDUFS5,ATP5F1A,ATP6V1C1,ATP6V0E1 |
| 8.056e-09 | -18.64 | Oxidative phosphorylation | KEGG pathways | ko00190 | 120 | 45 | 7161 | 1149 |
NDUFA5,COX5B,NDUFV2,COX15,NDUFS1,NDUFB6,UQCR10,COX4I1,NDUFA4,ATP5F1B,ATP6V1B2,ATP5PF,SDHA,NDUFS7,NDUFS4,ATP6V0B,NDUFV1,NDUFA2,NDUFB4,ATP6V0A2,NDUFS8,NDUFB9,CYC1,NDUFA3,PPA1,ATP6V0D1,ATP6V1G1,ATP6V0A1,NDUFA7,ATP5MF,NDUFB1,SDHB,ATP6V1D,ATP5MC3,COX7A2L,NDUFA11,COX8A,PPA2,COX5A,UQCRH,ATP6V0C,NDUFS5,ATP5F1A,ATP6V1C1,ATP6V0E1 |
| 8.191e-09 | -18.62 | SNRPD2 (small nuclear ribonucleoprotein D2 polypeptide) | protein interactions | 6633 | 130 | 48 | 17029 | 2761 |
SART1,MAPRE1,CYLD,SF3B1,SUZ12,CUL1,SNRPD3,CRLF3,LMNA,EIF4A3,GEMIN6,YBX1,GEMIN4,STRAP,LUC7L2,CDC5L,PRPF19,SNRNP200,ZCCHC10,SNRPB,SF3B6,CUL3,CRNKL1,DDX20,KRAS,PRPF3,MCM2,LUC7L,SF3A2,DHX15,CLNS1A,SUPT16H,DDX23,CAND1,GEMIN5,LSM6,LUC7L3,E2F4,DDX5,PRPF4,FUS,SNRPG,SNRNP70,CDK2,ARRB2,YWHAH,SMURF1,GEMIN7 |
| 8.191e-09 | -18.62 | MSH2 (mutS homolog 2) | protein interactions | 4436 | 130 | 48 | 17029 | 2761 |
SNX27,SART1,RECQL,MAX,ST13,ANXA6,RAF1,SUMO2,PMS2,PTP4A3,TOP2B,BLM,ATP6V1B2,DTL,RPA2,PCNA,ZNF746,XPA,MSH2,STAT3,MSH6,SRSF10,CDC5L,SRSF11,ERCC1,TK1,SEPT9,POLK,TOP3A,E2F3,RPS24,DNAJC9,USP10,BRCA1,SRSF5,DHX15,RPA1,XRCC5,SUPT16H,DPYSL3,RBM25,PFDN4,TPP2,E2F4,E2F1,CHEK2,CDK2,NMD3 |
| 8.232e-09 | -18.62 | GSE29164_UNTREATED_VS_CD8_TCELL_AND_IL12_TREATED_MELANOMA_DAY3_DN | MSigDB lists | GSE29164_UNTREATED_VS_CD8_TCELL_AND_IL12_TREATED_MELANOMA_DAY3_DN | 186 | 59 | 17377 | 2626 |
RECQL,CYLD,DEPDC1,ZCCHC8,RAF1,ANKH,RRM1,KIF23,NDUFA4,PXMP2,NUF2,AGFG1,S1PR2,OAT,XPO7,REEP5,TTF1,ARL6IP6,FBXO3,FANCL,RAP1A,SMC3,ATP13A3,TIMELESS,UBE3B,MOB1A,TNRC18,PPA1,VPS13B,SPTAN1,CCT2,SEPT9,HMGN5,NOA1,SLC26A6,GMFB,CDC6,OGDH,API5,PSMB3,ADSS,TAF2,FBXO28,WDR11,RAD18,DHX16,RBL1,MFAP1,RPS14,CEP55,SOCS4,OGT,RNF38,HMGB2,GPI,NCOA1,WDR62,GEN1,RHEBL1 |
| 8.232e-09 | -18.62 | GSE16266_CTRL_VS_HEATSHOCK_AND_LPS_STIM_MEF_UP | MSigDB lists | GSE16266_CTRL_VS_HEATSHOCK_AND_LPS_STIM_MEF_UP | 186 | 59 | 17377 | 2626 |
WSB2,UBE2D3,CMAS,TXN,UGP2,ZFP91,DBF4,COX4I1,AP3S1,GLRX3,TMEM165,FAM8A1,SF3B2,SLC25A36,PRNP,MOAP1,NDUFA2,ARPC5,RABGAP1L,PTPN11,EI24,AKR1B1,FEM1B,NFU1,RNF19A,MOB1A,LRRC59,F2R,TMBIM1,EEF1D,TMEM160,CCT2,ERMP1,RNASEH2C,ATXN1,KRAS,ODC1,TTC33,SF3A2,RPA1,NUCB1,GOLGA4,EIF4ENIF1,IDE,RBL1,NDUFA11,CEBPG,H2AFX,PPP1R11,COX5A,CHMP4B,ROCK1,ATP6V1C1,SASS6,RPS26,MYL12B,ATP6V0E1,CSNK1D,VPS29 |
| 8.251e-09 | -18.61 | MODULE_183 | MSigDB lists | MODULE_183 | 64 | 29 | 17377 | 2626 |
SRSF11,THOC1,CHERP,SRSF6,HNRNPF,SLBP,DHX8,SNRPD3,PCBP1,RBM4,PABPC4,SRSF1,DDX17,DDX23,HNRNPA2B1,HNRNPR,PPP1R8,GRSF1,KHSRP,TRA2B,RBM3,DUSP11,SRSF3,SNRPG,PABPC1,PCBP2,SRSF10,PRPF4B,SRPK2 |
| 8.723e-09 | -18.56 | GO_REGULATION_OF_PROTEASOMAL_PROTEIN_CATABOLIC_PROCESS | MSigDB lists | GO_REGULATION_OF_PROTEASOMAL_PROTEIN_CATABOLIC_PROCESS | 173 | 56 | 17377 | 2626 |
ZNF207,GORASP1,DNAJB2,SUMO2,UBXN1,CENPF,NKD2,CSNK2A1,SIRT2,UBQLN2,CCNB1,CSNK1A1,PRKACA,PSEN1,ANKIB1,BCAP31,PARK7,MAD2L2,FBXO22,DDRGK1,USP5,FBXO5,RAD23A,RB1,MDM2,PTEN,UCHL5,RAD23B,RNF19A,SENP1,SOCS5,PLK3,PLK1,UBQLN4,PBK,GBA,CUL3,RAB1A,PSMC4,GNA12,KEAP1,HSPBP1,GOLGA2,NSMCE2,SOCS4,XRCC3,DVL1,CLU,RNF14,GEN1,PSMC1,TERF1,ESPL1,CSNK1D,SVIP,RNF114 |
| 8.931e-09 | -18.53 | LIAO_METASTASIS | MSigDB lists | LIAO_METASTASIS | 487 | 121 | 17377 | 2626 |
CCDC93,PLXNC1,LUZP1,NQO1,AGRN,FOXM1,TRIP10,GNPDA1,URB2,SLC2A1,OLA1,PTP4A3,TBC1D13,NUF2,GYG1,PLXNA1,USP48,DUSP22,MYEF2,SNAPC4,MXD1,MEAF6,DLG5,SHC1,STRBP,ZNF302,PDCD2,C8orf59,CLTB,CLN6,SMARCE1,ZC3H3,TACC3,USP34,POU2AF1,ORAI2,DEAF1,SEPT9,MAP4K4,SLC16A7,NLN,GORAB,SOX4,TMEM201,RAD54B,SOCS7,ZMYM3,MAP3K4,KIF2A,ANKRD10,DNAJC10,MKNK1,PWWP2B,DDOST,KIF18B,MAP4,ATXN2L,BRD9,TRAF5,COX5B,PKP4,HJURP,AGTRAP,SESTD1,CHTF18,TCF3,NACA,TKT,DLGAP4,CDK13,WDR5,TMEM165,MFSD10,JMY,SAC3D1,SLC25A36,UBE2Q2,ATIC,PPIL2,ARHGEF1,GTSE1,ARHGEF2,CENPM,ALDH18A1,IFRD1,PIGT,TSTA3,PRRC2A,USP42,MRS2,MYBL2,ADSL,KCNQ1,OTUD3,CBFA2T2,SF3A2,SNRPA,MAPK3,GNAS,TPD52L2,SGSH,FBXO41,MTHFD2,ZNF777,ATAD2,SYNCRIP,TTLL4,BIRC5,FAM110A,NEIL3,CDCA7L,LRPPRC,E2F1,SLC25A19,RUVBL2,NDE1,RBBP4,HRAS,ZC3HAV1,N4BP2L2,DEF6 |
| 9.083e-09 | -18.52 | CSNK2B (casein kinase 2 beta) | protein interactions | 1460 | 288 | 85 | 17029 | 2761 |
RORB,BCCIP,SARNP,ATXN3,ADD1,PHRF1,SUZ12,RPS6KA1,SUMO2,PTTG1,HEXB,CSNK2A1,KIF2C,UBE2I,MAPK14,LYN,SDHA,MBD4,PRNP,ANKRD28,PHC2,HNRNPA2B1,SEC11A,NRF1,MDM2,CIPC,PIN1,RPAP1,CDC25B,TP53BP2,EIF5,DNMT1,SPSB3,PTPRK,RYBP,USO1,PCGF6,RNPS1,BRCA1,VDAC1,ODC1,FKBP3,EIF3H,SUPT16H,PPP2CA,BRD2,ARNTL,OGT,ACTB,BTF3,NKAPD1,COIL,POT1,CBX4,SSRP1,CTDP1,UNK,TOP2B,BLM,PIP4K2A,WDR48,EIF2S2,MLX,GRK2,TERF2,AMPD2,STAU1,TCTEX1D2,SNX2,CIC,WDR1,WDR18,PIP4K2C,CDK11A,NMT2,RPA1,NAP1L1,UPF1,PML,PITPNA,CD81,TERF1,NRBP1,FAF1,IFI16 |
| 9.083e-09 | -18.52 | GSE41867_DAY6_VS_DAY8_LCMV_CLONE13_EFFECTOR_CD8_TCELL_DN | MSigDB lists | GSE41867_DAY6_VS_DAY8_LCMV_CLONE13_EFFECTOR_CD8_TCELL_DN | 182 | 58 | 17377 | 2626 |
UBL3,EYA1,PDAP1,GNE,LETMD1,ARFIP2,MYNN,SLC35B1,DCUN1D4,RUFY1,PITHD1,BZW2,MRPL19,CDC73,PAIP1,PCYOX1L,WWP2,ADD3,GATC,THAP4,HUWE1,SLC44A1,PPP4R1,TXLNA,RP2,RNF19A,PDIA6,MCMBP,MAPRE2,GABPA,NOA1,TMEM126B,AACS,OXR1,PCGF6,GALK2,CYFIP2,ICAM2,EIF3G,EML4,RPSA,NSA2,SH3BP5,ZNF317,PPP2R5A,TTC13,UAP1,SYNCRIP,STT3A,ZHX1,SNAP23,KBTBD7,SIAH2,ACADM,CDK2,CPEB2,ZBTB24,NXT2 |
| 9.107e-09 | -18.51 | Cellular responses to stress | REACTOME pathways | R-HSA-2262752 | 451 | 121 | 10287 | 1696 |
CHMP2A,PRKAB1,NDC1,H2AFZ,TXN,NUP188,ST13,TSC2,UBN1,RPS6KA1,SUZ12,DYNLL1,RRAGC,MAP1LC3B,MAPK14,BECN1,PHC2,TERF2IP,CDKN2C,MDM2,PSMD1,CCNA2,NUP210,PSMA6,ATG3,NUP107,CDKN1B,ANAPC7,NUP153,SEH1L,MLST8,PSMA8,RBX1,ERF,ATG9A,VHL,MAP4K4,EHMT1,E2F3,PSMB7,NUP155,CDC23,CHMP2B,PSMB9,H2AFV,RHEB,HSPA4,CHMP4A,CDC16,RPS27A,PSMD8,PSMD3,PRDX5,H2AFX,CHMP4B,TFDP2,H3F3A,E2F2,MAPK1,PSMC1,POT1,CBX4,AAAS,UBE2D3,DNAJC2,HSPH1,RAE1,PRKAA1,LAMTOR3,NUP54,CYCS,AKT1S1,DNAJB1,ETS1,PSMD9,NUP205,ATG4A,RPA2,RB1,PSMD2,ATG13,PTGES3,CITED2,STAT3,NUP85,CAMK2G,TERF2,RB1CC1,MAPKAPK3,ERO1A,PSMA1,ANAPC2,PSMB3,PRDX1,HSPA1B,MAPK3,PSMC4,RPA1,MTMR3,CAT,TSC1,CDC27,ETS2,PRDX3,LAMTOR4,TFDP1,E2F1,NUP62,CABIN1,WIPI2,MAP3K5,RBBP4,CDK2,CHMP7,WDR45B,UBE2C,NUP58,TERF1,ANAPC4,CDKN2A,EGLN1 |
| 9.218e-09 | -18.50 | NUP153 (nucleoporin 153) | protein interactions | 9972 | 111 | 43 | 17029 | 2761 |
IER2,NDC1,NUP188,PRKCSH,RAE1,SUMO2,NUP54,XPO7,UBE2I,MAPK14,NUP205,LMNA,KIFC1,PPP1R3B,NUP210,MEA1,NUP107,NUP153,GLE1,SMARCE1,NUP85,SENP1,SEH1L,TDP1,CUL3,NUSAP1,CDCA2,NUP155,RANGAP1,BRCA1,NUTF2,MAPK3,KPNA4,KPNA1,SMAD2,USP20,NUP62,KPNA2,SMPD4,USP11,MAPK1,AAAS,IFI16 |
| 9.230e-09 | -18.50 | REACTOME_METABOLISM_OF_MRNA | MSigDB lists | REACTOME_METABOLISM_OF_MRNA | 209 | 64 | 17377 | 2626 |
RPLP2,RBM8A,MAPK14,PAIP1,EDC3,RPL11,RPL23A,PSMD1,PSMA6,EIF4A3,EXOSC1,RPL29,EXOSC6,RPL35,PSMA8,RNPS1,PSMB7,RPL38,PSMB9,RPS9,RPSA,PPP2CA,RPL37,LSM6,RPS27A,PSMD8,RPS14,PSMD3,RPLP1,SMG9,FAU,PSMC1,RPS26,RPS15,RPS2,GSPT2,RPL15,PARN,PSMD9,CNOT3,PSMD2,EXOSC7,RPL17,ANP32A,DCP1A,UPF2,RPL19,PABPC1,RPL8,RPL6,RPS10,RPS24,PSMA1,EXOSC9,RPL27A,PATL1,PSMB3,RPL36,PSMC4,HSPA1B,RPL32,KHSRP,YWHAZ,CNOT6 |
| 9.269e-09 | -18.50 | SREK1 (splicing regulatory glutamic acid and lysine rich protein 1) | protein interactions | 140890 | 85 | 36 | 17029 | 2761 |
NIFK,SRSF6,CUL1,CSNK2A1,JMJD6,THRAP3,SNRPD3,PAIP1,PABPC4,HNRNPA2B1,MDM2,PIN1,SRSF4,EFTUD2,TRA2B,YBX1,PABPC1,LUC7L2,SRSF10,SRPK2,CDC5L,SRSF11,RNPS1,SREK1,SRSF5,SUPT16H,DDX17,SRSF1,RBM25,RBMX,SAFB,SH3GLB2,ZRANB2,SRSF3,RRS1,SSRP1 |
| 9.279e-09 | -18.50 | GSE360_HIGH_DOSE_B_MALAYI_VS_M_TUBERCULOSIS_DC_UP | MSigDB lists | GSE360_HIGH_DOSE_B_MALAYI_VS_M_TUBERCULOSIS_DC_UP | 191 | 60 | 17377 | 2626 |
USP7,NCOR2,H2AFZ,GMFG,ADD1,UBN1,KLHL21,PHB2,DAP,HEXB,TKT,NKRF,AP1B1,PABPC4,NDUFS7,TFAP4,TBC1D22A,SIVA1,BDH1,ADCY9,ANP32A,SLC38A10,AHCYL1,STRAP,HNRNPM,PCBP2,KDELR1,SPTAN1,CDC5L,DEAF1,MLEC,TIMP2,AATF,SEPT9,ERF,CDC123,DCAF8,TUFM,H2AFV,TXNL4A,ECH1,FADD,STOML2,MAGED2,SEC31A,MAN2A2,PON2,CSK,RPS14,ATXN2L,WDR7,HMGB2,DDX5,SCARB1,WIPI2,ZMIZ1,LTA4H,YWHAH,GCSH,DDX42 |
| 9.712e-09 | -18.45 | spindle organization | biological process | GO:0007051 | 151 | 51 | 17256 | 2622 |
BCCIP,ZNF207,KIF3B,MZT1,MECP2,POC1A,DCTN2,XIAP,TPX2,MYH9,KIF23,HAUS4,RACGAP1,NUF2,CCNB1,STMN1,RAB11A,HAUS2,BIRC2,TUBGCP2,SPAG5,FBXO5,KIFC1,STARD9,NEK6,ABRAXAS2,PRC1,CEP63,RHOA,BIRC3,ASPM,NEK7,INTS13,MYBL2,TUBGCP5,EZR,AURKB,KIF11,HAUS8,KIF2A,GOLGA2,BIRC5,CHD3,GOLGA8A,MAP4,CCDC69,CHEK2,WDR62,ESPL1,TUBB,CSNK1D |
| 9.714e-09 | -18.45 | EIF2AK2 (eukaryotic translation initiation factor 2 alpha kinase 2) | protein interactions | 5610 | 115 | 44 | 17029 | 2761 |
COX15,RPS2,NOP2,MECP2,RAC1,DHX9,KCTD17,EBNA1BP2,PABPC4,LMNA,LYAR,FARSA,CCNA2,STRBP,CDC42,PTEN,MAVS,PTGES3,STAT3,FTSJ3,CDC37,IFRD1,STAU1,RPL6,GTPBP4,CUL3,ILF3,EIF2A,PRKRA,MCM2,TOLLIP,ISG15,CAND1,SCARB2,PPP2R5A,JAK1,TAB2,CDCA5,STAT1,CHMP4B,MAP3K5,TRAF5,PURA,IFI16 |
| 9.821e-09 | -18.44 | GO_INNER_MITOCHONDRIAL_MEMBRANE_PROTEIN_COMPLEX | MSigDB lists | GO_INNER_MITOCHONDRIAL_MEMBRANE_PROTEIN_COMPLEX | 79 | 33 | 17377 | 2626 |
NDUFA5,NDUFV2,IMMT,NDUFS1,NDUFB6,UQCR10,NDUFA4,COX4I1,SDHA,PARK7,NDUFS7,NDUFS4,NDUFV1,NDUFA2,NDUFB4,TIMM23,NDUFB9,NDUFS8,APOOL,NDUFA3,TIMM50,PPIF,NDUFA7,NDUFB1,FOXRED1,CHCHD6,CHCHD3,SDHB,TIMM17A,NDUFA11,COX8A,COX5A,NDUFS5 |
| 9.912e-09 | -18.43 | MORF_CUL1 | MSigDB lists | MORF_CUL1 | 68 | 30 | 17377 | 2626 |
KARS,IMMT,SNRNP200,POLR2I,NUP188,HNRNPAB,AATF,SUMO2,STARD7,CUL1,XPO7,EIF4H,SDHA,POLR2A,HNRNPA2B1,PPP2CA,DNAJC8,EIF2S2,ARPC5,TXLNA,LRPPRC,CS,CAPZA1,NUP62,MDH1,TARDBP,DDB1,HNRNPM,HDAC2,SMNDC1 |
| 1.000e-08 | -18.42 | GSE37416_0H_VS_3H_F_TULARENSIS_LVS_NEUTROPHIL_UP | MSigDB lists | GSE37416_0H_VS_3H_F_TULARENSIS_LVS_NEUTROPHIL_UP | 178 | 57 | 17377 | 2626 |
RECQL,FEZ2,PDCD6IP,PNISR,ADD1,ACAP1,TATDN3,CSNK2A1,ARGLU1,INO80E,SLC25A44,RMI1,CNOT3,C2orf68,TMEM69,NRF1,CCP110,TBC1D22A,RABGAP1L,TTC9C,SRSF4,NSFL1C,UPF2,UBE3B,MVP,SLC35A1,CAMK2G,TMX1,RPAP3,ATP13A1,AGGF1,NASP,SNX2,RAB7A,OXR1,AMD1,HTATIP2,NDUFB1,MARK2,SMAP2,ASF1B,EPB41,SUPT16H,TSC1,RAB18,HSPB11,DSN1,VPS26B,OSBPL8,SNAP23,HIPK2,LUC7L3,MBOAT1,SNRNP70,CAPN1,GEMIN7,PRPF4B |
| 1.005e-08 | -18.42 | Influenza Viral RNA Transcription and Replication | REACTOME pathways | R-HSA-168273 | 137 | 50 | 10287 | 1696 |
RPS15,NDC1,RPS2,NUP188,RPLP2,POLR2K,RAE1,NUP54,RPL15,NUP205,GTF2F1,RPL11,RPL23A,NUP210,RPL17,GRSF1,NUP107,NUP153,RPL19,RPL22L1,NUP85,SEH1L,RPL29,RPL35,POLR2I,POLR2L,POLR2G,RPL8,RPL38,POLR2D,RPL6,RPS10,RPS24,NUP155,RPL27A,RPS9,POLR2A,RPSA,RPL36,RPL37,RPL32,POLR2J,RPS27A,RPS14,RPLP1,NUP62,FAU,RPS26,NUP58,AAAS |
| 1.013e-08 | -18.41 | GTF2I (general transcription factor IIi) | protein interactions | 2969 | 119 | 45 | 17029 | 2761 |
USP7,EWSR1,SUZ12,PTP4A3,UBE2I,MAD2L2,RPA2,TFAP4,ZNF428,USF1,MDM2,KMT5C,RAD23B,AP2B1,STAT3,GCC1,POU2AF1,METTL1,CCT2,PRKDC,CUL3,ADSL,LSM8,TOPORS,NFATC2IP,BRCA1,POLR2A,MAPK3,CHAF1A,ZMYM3,RPA1,NUCB1,SMAD2,TAB2,TULP3,PRPS2,STAT1,PTAR1,PIAS2,ATF6,YY1,CDK2,MAPK1,CBX4,HDAC2 |
| 1.013e-08 | -18.41 | PES1 (pescadillo ribosomal biogenesis factor 1) | protein interactions | 23481 | 119 | 45 | 17029 | 2761 |
SART1,NIFK,NOP2,FOXM1,CXXC1,MYH9,CSNK2A1,EBNA1BP2,BRIX1,APP,KRR1,NVL,RRBP1,NOC2L,RPF2,NAP1L4,FBL,TNRC18,FTSJ3,DDX24,ELOA,GTPBP4,RNPS1,CUL3,RPL8,RPL38,PFKFB3,C1orf35,RPL27A,DHX15,SUPT16H,CAND1,RPL36,NSA2,UBTF,KIF2A,NAP1L1,TRIM26,BRD2,NIP7,KBTBD7,RRS1,ARRB2,ZC3HAV1,IFI16 |
| 1.014e-08 | -18.41 | SIN3A (SIN3 transcription regulator family member A) | protein interactions | 25942 | 205 | 66 | 17029 | 2761 |
MAX,ADD1,KMT2E,CSNK2A1,SMARCA4,MXD1,MBD4,SAP130,PA2G4,THADA,MTA1,ETV6,SEPT11,AHCYL1,SMARCE1,SAP30L,ARID4A,RLIM,SAP30,KLF10,DDX20,TOPORS,MIER2,MBD3,TRIM28,BRMS1,HINT1,CHD3,TAB2,E2F4,OGT,CAB39,SINHCAF,HDAC2,FUBP1,NCOR2,UNK,PHF23,MECP2,CTCF,KLF13,MXD4,NOTCH2,TFAP4,KLF16,MBD2,HDAC7,TTLL12,STAT3,FOXK1,MTA2,MEN1,CBFA2T2,ISG15,IRF5,PFDN5,GPS2,PML,KHSRP,CABIN1,RBPJ,RBBP4,IGBP1,PDLIM5,TAF6,DDB1 |
| 1.039e-08 | -18.38 | catalytic step 2 spliceosome | cellular component | GO:0071013 | 100 | 38 | 18223 | 2701 |
SART1,CDC40,ZCCHC8,XAB2,SF3B1,RBM8A,DHX8,SNRPD3,SF3B2,HNRNPA2B1,NSRP1,CWC27,EIF4A3,EFTUD2,BUD31,GPATCH1,AQR,PABPC1,HNRNPM,CDC5L,PRPF19,SNRNP200,SNRPB,PPIE,SF3B6,HNRNPF,CRNKL1,PPWD1,SF3A2,SRSF1,DDX23,SYNCRIP,HNRNPR,RBMX,DDX5,SNRPG,WDR62,PRPF4B |
| 1.064e-08 | -18.36 | LIN28A (lin-28 homolog A) | protein interactions | 79727 | 89 | 37 | 17029 | 2761 |
HNRNPAB,NOP2,HNRNPUL2,DHX8,EBNA1BP2,SND1,BRIX1,SRRT,SF3B2,KRR1,KRI1,STRBP,RBM34,FBL,HP1BP3,CDC5L,PRPF19,PPAN,SRP72,AATF,NOA1,SNRPB,SREK1,PRPF3,SNRPA,DHX57,DOT1L,UPF1,KPNA4,TCOF1,SNRPG,RRS1,SNRNP70,ZBTB11,PURA,ZC3HAV1,BYSL |
| 1.064e-08 | -18.36 | PAICS (phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthase) | protein interactions | 10606 | 89 | 37 | 17029 | 2761 |
MIF,UNK,UGP2,PRKCSH,TKT,ARF1,PCBP1,CDC73,NDUFV1,GART,HUWE1,ATIC,RPAP1,CRY2,IMPA2,TACC3,ABCC1,MOB4,STAU1,POLR2G,CUL3,ADSL,BRCA1,PKM,MCM2,GINS4,GLOD4,EPB41,PSMC4,GNAS,HLA-B,CHD3,FUS,CDK2,TERF1,SSSCA1,SMARCD1 |
| 1.065e-08 | -18.36 | SOX2 (SRY-box 2) | protein interactions | 6657 | 353 | 99 | 17029 | 2761 |
TCF12,USP7,ZBTB10,TRERF1,MRPL39,OLA1,TAF6L,BRIX1,SEC16A,KCMF1,MYEF2,RBM4,PHC2,SAP130,INTS1,MTA1,ETV6,SRSF4,RAD23B,ANAPC7,AHCYL1,RBM15,USP34,SRP72,ENPP4,MKLN1,MRPL12,LSM8,DNAJA1,SMC2,CDC23,SHCBP1,MBD3,SUPT16H,TAF2,PAF1,DAP3,CHD3,LSM6,NIP7,PRPF4,ANP32E,CBX4,PFKP,HDAC2,INTS2,RMND5A,NCOR2,MRPL9,ZCCHC8,MECP2,RAE1,TCF3,MRPS26,TIA1,CDC73,SCYL2,CNOT3,CAPN2,SMC3,INTS7,MBD2,TNPO3,ANP32A,CTR9,NAP1L4,TNRC18,PPP6R1,MED22,SAMD4B,GID8,ETV3,MTA2,TEX10,MIER1,SUGP2,ANAPC2,RANGAP1,ARID1A,DDX39A,MACF1,ARMC8,CDK11A,PICALM,CYB5A,XRCC5,MAGED2,KPNA4,OSBPL11,TRIM26,PDLIM1,MFAP1,YWHAZ,RUVBL2,ATP5F1A,RBBP4,ANAPC4,IPO4,SMARCD1 |
| 1.094e-08 | -18.33 | DKC1 (dyskerin pseudouridine synthase 1) | protein interactions | 1736 | 147 | 52 | 17029 | 2761 |
BCCIP,COX15,NIFK,NOP2,SUZ12,CSNK2A1,JMJD6,RBM4,PARK7,LMNA,WDR48,SSR1,KRR1,DDX56,RBM34,NOC2L,RPF2,DDX31,PTGES3,FBL,ZC3H3,FTSJ3,LYPLA2,TERF2,NOL12,PPAN,STAU1,NASP,DDX24,ABCF2,GTPBP4,RPL8,VDAC1,GAR1,MAK16,DHX15,RPSA,CAND1,SYNCRIP,DGCR8,TBL3,MAPK6,H2AFX,RUVBL2,TCOF1,RRS1,SNRNP70,ARRB2,NMD3,ZC3HAV1,IFI16,GPATCH4 |
| 1.099e-08 | -18.33 | GSE17974_0H_VS_24H_IN_VITRO_ACT_CD4_TCELL_DN | MSigDB lists | GSE17974_0H_VS_24H_IN_VITRO_ACT_CD4_TCELL_DN | 174 | 56 | 17377 | 2626 |
TMEM106C,WSB2,POLA2,MMACHC,LZTR1,PHF23,PDAP1,CDK2AP2,UCK2,TPX2,RMI2,SLC29A1,SDF2L1,CHAC2,BLM,NCAPG,TCF19,TMEM165,POLR3K,PNO1,FBXO22,BCAT2,CDK5,LYAR,SNRNP25,HOMER1,CCNA2,SLC38A5,CENPJ,BDH1,ZDHHC13,PRC1,GEMIN6,RNASEH2A,CENPM,UBE2M,GM2A,WDR41,JMJD4,MRPL12,SCFD2,MYBL2,FANCE,SLC19A1,CCDC86,BIRC5,CDCA5,DNAJC17,H2AFX,BAZ1B,SMG9,UBE2C,APOL2,PDCD2L,RAD51D,BYSL |
| 1.111e-08 | -18.32 | RPS13 (ribosomal protein S13) | protein interactions | 6207 | 180 | 60 | 17029 | 2761 |
RPS15,RPS2,CYLD,RPLP2,TCF3,RPL15,CUL1,BRIX1,KCMF1,HAUS2,PNO1,RPL11,RPL23A,PTEN,RPL17,HUWE1,RBM34,AHSA1,RPL19,MAP3K14,FBL,HNRNPM,PPAN,LARS,EIF3L,RPL35,RPS10,RPL6,TUFM,RNPS1,CUL3,ILF3,RPL8,RPL38,RPS24,BRCA1,EIF2A,MCM2,RPL27A,RPS9,RPSA,RPL36,CAND1,RPL37,RPL32,DGCR8,RPS27A,RPS14,PSMD3,RPLP1,RRS1,FAU,CDK2,ARRB2,SMURF1,CD81,RPS26,PSMC1,ZC3HAV1,PDCD4 |
| 1.117e-08 | -18.31 | SDHB (succinate dehydrogenase complex iron sulfur subunit B) | protein interactions | 6390 | 104 | 41 | 17029 | 2761 |
NDUFV2,NDUFS1,NDUFB6,SUCLG1,MDH2,HNRNPUL2,CUL1,NDUFA4,COX4I1,ATP5F1B,SDHA,RSAD1,NDUFS4,RAB8A,NDUFV1,NDUFA2,TXLNA,CS,NDUFB9,NDUFS8,MRPL48,MRPL40,TMED2,TIMM50,RAB7A,LDHA,TOP3A,CUL3,MRPS10,SLC25A22,TOMM40,MAT2A,IWS1,CAND1,UAP1,ACLY,ACAT1,PTPDC1,GPI,PREPL,ABCA1 |
| 1.124e-08 | -18.30 | PTP4A3 (protein tyrosine phosphatase type IVA, member 3) | protein interactions | 11156 | 45 | 24 | 17029 | 2761 |
USO1,SMAP1,NUP188,DNAAF5,SMC2,UBE4A,XPO7,NCAPG,PRPSAP1,FANCI,FNTA,ATP2A2,HUWE1,PSMD3,LRPPRC,MSH2,TNPO2,CDK2,CNNM3,ECPAS,IPO4,CDKN2A,HNRNPM,TMEM33 |
| 1.133e-08 | -18.30 | GSE3720_UNSTIM_VS_PMA_STIM_VD1_GAMMADELTA_TCELL_UP | MSigDB lists | GSE3720_UNSTIM_VS_PMA_STIM_VD1_GAMMADELTA_TCELL_UP | 161 | 53 | 17377 | 2626 |
DDX58,COX5B,CXXC1,NACA,DLGAP4,UBE2Q1,CREBL2,GFM2,PIP4K2A,NDUFS7,ERH,MLX,PSMA6,RINL,MCM5,RCSD1,GPATCH1,NDUFB9,RPL19,ZBTB22,PDLIM2,CDC37,PPAN,KAT2A,RNASEH2C,VHL,RPL8,MRPL16,PACS1,BOLA1,UTP3,MEF2D,WDR81,LY6E,ODC1,H2AFV,RPSA,EIF3H,CYB5A,RPL32,RBM25,RPS27A,CHD3,RPS14,ERGIC3,COX5A,HMGB2,CHMP4B,MBOAT1,HEXA,EYA2,VPS29,STARD3NL |
| 1.136e-08 | -18.29 | GSE37532_TREG_VS_TCONV_PPARG_KO_CD4_TCELL_FROM_LN_UP | MSigDB lists | GSE37532_TREG_VS_TCONV_PPARG_KO_CD4_TCELL_FROM_LN_UP | 183 | 58 | 17377 | 2626 |
CMAS,SKA3,NSMCE4A,H2AFZ,UROD,DBF4,VPS45,CDCA8,MED13L,KIF23,CTCF,SMARCA4,CBLL1,NUF2,DCUN1D4,NCAPG,MBD4,TERF2IP,KIFC1,C1GALT1,NFATC3,CCP110,NUP107,MSH2,ARL6IP1,AKR1B1,ANAPC7,MYBL1,IFT46,CTDSP2,HP1BP3,TERF2,MND1,USO1,POLR2G,HMGN5,GOPC,NUDT4,MKI67,LNX2,CKAP2L,CCNF,KIF11,SDHB,FNTA,SEC23IP,KIF18B,BRWD1,UAP1,PRPS2,KLHDC4,SMPD4,TFDP2,REEP4,SASS6,NGLY1,ESPL1,SLC25A33 |
| 1.136e-08 | -18.29 | GSE24634_IL4_VS_CTRL_TREATED_NAIVE_CD4_TCELL_DAY7_UP | MSigDB lists | GSE24634_IL4_VS_CTRL_TREATED_NAIVE_CD4_TCELL_DAY7_UP | 183 | 58 | 17377 | 2626 |
TMEM106C,C19orf53,MAGED1,UROD,PTTG1,TPX2,TMEM97,CDCA8,KIF23,RACGAP1,KIF2C,CCNB1,NCAPG,STMN1,IL21R,FANCI,SPAG5,DTL,C12orf10,OIP5,SNRNP25,CCNA2,TBC1D22A,TPST1,CDC25B,FBL,SGCB,HTRA2,TRIM14,RNF5,ABCC5,TDP1,TK1,SNX2,AKT2,RAD51AP1,KIF15,MKI67,EMP3,RRM2,NUSAP1,ARHGDIB,AURKB,NDUFA7,MCM2,NDUFB1,KIF11,BIRC5,WNT5B,QARS,PPA2,ACAT1,HMGB2,RGL1,UBE2C,CCNB2,ESPL1,TUBB |
| 1.140e-08 | -18.29 | GNF2_TTK | MSigDB lists | GNF2_TTK | 38 | 21 | 17377 | 2626 |
CCT2,HJURP,FOXM1,ASPM,CENPF,DBF4,TPX2,RRM1,RACGAP1,NUSAP1,KIF2C,SMC2,MCM2,KIF11,FANCI,CCNA2,PCNA,KIF18B,PRC1,CCNB2,SMC4 |
| 1.160e-08 | -18.27 | RPS15A (ribosomal protein S15a) | protein interactions | 6210 | 176 | 59 | 17029 | 2761 |
RPS15,NIFK,RPS2,CYLD,EWSR1,NOP2,RPLP2,RPL15,CUL1,PNO1,RPL11,RPL23A,PSMD1,PTEN,RPL17,HUWE1,AHSA1,ZNF746,EXOSC1,RPL19,FBL,HNRNPM,CDC37,RPL29,RPL35,VHL,RPS10,RPL6,TUFM,CUL3,ILF3,RPL8,RPL38,RPS24,MRPL16,BRCA1,MCM2,RPL27A,SLC25A5,MRPS14,RPS9,RPSA,RPL36,CAND1,RPL37,GALNT2,RPL32,RPS27A,RPS14,PSMD3,RPLP1,ATP5F1A,COPS6,FAU,CDK2,SMURF1,RPS26,PSMC1,TUBB |
| 1.161e-08 | -18.27 | histone modification | biological process | GO:0016570 | 356 | 95 | 17256 | 2622 |
USP7,ASH1L,KDM4A,KMT2E,UBR2,SUZ12,CXXC1,NSD3,TAF6L,SIRT2,CCNB1,MEAF6,TET3,CCNA2,BRPF3,KMT5C,KDM2A,MTA1,TAF5L,ATF2,SAP30L,ARID4A,CARM1,RYBP,SAP30,KDM3B,BAZ2A,KAT7,EHMT1,RIOX2,PCGF6,ELP4,MIER2,WDR82,USP22,AURKB,KDM1B,KMT2C,MBD3,USP21,USP36,DOT1L,PAF1,BRMS1,CHD3,OGT,BAZ1B,BEND3,NCOA1,PPP5C,NAA60,EYA2,HDAC2,EYA1,MECP2,PRKAA1,JMJD6,EZH1,WDR5,SUPT7L,RLF,CDC73,IRF4,SUV39H2,HUWE1,KMT5A,HDAC7,PRDM4,ZNF335,NAA50,CTR9,KANSL2,FBL,KAT2A,MTA2,MIER1,LDB1,RCOR1,RTF1,MEN1,PRMT2,PCGF1,KDM3A,MBIP,EPOP,SETD3,TEX30,KMT2B,PRMT7,RUVBL2,TAF12,RBBP4,CDK2,SGF29,DDB1 |
| 1.161e-08 | -18.27 | KIF2B (kinesin family member 2B) | protein interactions | 84643 | 42 | 23 | 17029 | 2761 |
CEP170B,CCDC93,STAU1,KLC1,SIKE1,KIF2C,CDC23,COMMD6,COMMD8,DAPK3,MIS12,HOMER1,NEK1,CDC16,DSN1,KIF18B,POLR2J,CDC27,TXLNA,FEM1B,C4orf46,WDR62,ASB6 |
| 1.171e-08 | -18.26 | GNF2_ESPL1 | MSigDB lists | GNF2_ESPL1 | 35 | 20 | 17377 | 2626 |
PLK1,FOXM1,ASPM,TPX2,MKI67,CDCA8,RRM2,KIF2C,AURKB,SMC2,KIF11,SPAG5,ASF1B,CCNA2,PCNA,BIRC5,CENPM,CCNB2,UBE2C,ESPL1 |
| 1.177e-08 | -18.26 | transferase activity | molecular function | GO:0016740 | 2446 | 471 | 17224 | 2647 |
FGFR1OP,GXYLT1,MAP3K7CL,CXXC1,ZDHHC8,PIGQ,HEXB,XIAP,AGPAT1,CUL1,NHLRC3,GYG1,NANS,OAT,CCNB1,UBE2I,POLR3K,FBXO22,EEF2K,CDK5,NEK6,FBXW2,UPRT,TAF5L,MAST2,MARCH2,RNF26,SPTSSA,TIPARP,SMARCE1,ZNRD1,DNMT1,MGAT5,FTSJ3,PLK3,AKT2,PBK,NSUN2,EHMT1,TOPORS,AURKB,GALNT7,USP22,ICMT,CCNF,PRIM1,DOT1L,MAP3K4,MKNK1,RAD18,STT3A,LIMK1,WDR4,OGT,ATE1,ST3GAL2,RNASEL,KLHL42,FBXL3,CHPF2,ZNF598,PFKP,B4GALT2,ZNF720,POLR2K,DHPS,PRKAA1,TRIO,CERK,B4GALT1,ZNRF3,EZH1,EIF2AK4,SUPT7L,METTL3,NDUFAF6,RNF121,RPN1,MEX3C,KLHL5,ZNRF2,RNFT1,HDAC7,DAD1,ATIC,FBXO7,TPST1,DAPK1,PIGG,FBXL7,PCYT2,RNF135,PIKFYVE,LPCAT1,MRM3,PHKG2,NSUN4,TERF2,UBE2QL1,FDFT1,PRIM2,MAPKAPK3,COQ8A,PGS1,PIP4K2C,MFNG,ARMT1,PKM,MAP2K2,MTR,TWISTNB,PI4K2A,FNTA,POLR2J,CSK,DCK,CSNK1G1,TEX30,SETD3,LPCAT4,ACLY,PTAR1,PIAS2,SAMD8,MAP3K5,CDK2,RNF14,HEXA,RNF139,NRBP1,ZC3HAV1,TRIM41,KARS,TP53RK,DNMT3A,UBR2,SUZ12,RPS6KA1,RAF1,RAC1,KLHL18,RXYLT1,ADPGK,PRKACA,LCLAT1,ANKIB1,CPNE3,FLAD1,PRKD3,FBXL6,CCNA2,SIAH1,CDKN1B,TTC3,RNF19A,TALDO1,ATF2,NAA35,CDK12,PDCL3,RNF169,MRM2,ULK3,POLR2L,KAT7,MAP4K4,TAOK1,CUL3,POLR2D,PFKFB3,ELP4,KIAA1586,GALK2,EDF1,PKMYT1,CDC23,TAZ,POLG2,TRIM28,MAT2A,PRDM11,DDOST,JAK1,CERS6,NSMCE2,HIPK2,CAMKMT,FTSJ1,RNF38,MBOAT1,TRIM32,PDXK,B4GALT3,CSNK1D,POLQ,PRPF4B,GALK1,B4GALT5,ZFP91,TKT,BRAP,CBLL1,AGPAT3,SDF2L1,IP6K2,UBE4A,WDR5,PMVK,POFUT1,TUT4,NEXMIF,PIP5K1C,WWP2,FBXO3,RFWD3,CCNK,CLIC4,SUV39H2,HUWE1,CRAT,PRDM4,FUT8,PTPN11,NAA50,FEM1B,LTN1,KANSL2,UBE3B,OSTC,MAP3K14,ST8SIA2,GTF2H2,FBXL19,UBE2M,PDPK1,TK1,GUK1,TNFAIP3,LONRF3,KAT2A,POLK,NEK7,PARP4,TBRG4,FBXO9,ANAPC2,MARK2,POLR2A,ZNF862,FBXO21,KEAP1,POLE,LTBP4,MAGT1,MAPK6,PPP1R11,PARP10,ANAPC4,SRM,POLA2,CCNC,MIB2,PIGM,NAT9,UBE2E2,NOP2,KMT2E,HMGXB3,TRIM11,UBE2Q1,CSNK2A1,UBE2Z,SIRT2,TAF6L,CDIPT,MAPK14,KCMF1,BIRC2,RNF103,ZER1,BCAT2,PAPOLA,ABL2,FANCL,CDC42,GOT2,ATG3,METTL14,PIK3R2,TRMU,HADHB,FAM86C1,FGFR1OP2,CARM1,SRPK2,CDC37,METTL1,PLK1,TRIM8,DPM1,RBX1,VHL,TLK1,WDR82,UBE2V1,BRCA1,KMT2C,PRPSAP1,STK17B,ABHD5,ALG3,TRIM4,AGPAT2,BAZ1B,CAB39,CRCP,STK11,CHEK2,GALNT10,ROCK1,OSGEPL1,CHPT1,NAA60,SEPHS2,UBE2D3,CTU2,RMND5A,PARP12,PIGN,UFC1,ADCK5,CDK13,B4GALT4,CHKA,DTL,C1GALT1,NUS1,UBE2Q2,MED10,CMTR2,PPIL2,UBE3C,ALDH18A1,LRSAM1,N4BP2,CSNK1G3,POLR2I,MAP4K3,EIF2AK1,UBE4B,SYVN1,METTL22,ZDHHC3,NMT2,DAPK3,MASTL,MBIP,GALNT2,UAP1,KLHL15,PRPS2,SIAH2,ZDHHC7,FN3KRP,PRMT7,TRMT10B,NAA20,CCNB2,PTDSS1,PDSS2,RNF114,PRKAB1,GLT8D1,ASH1L,TRAF7,UGP2,GNPNAT1,MPHOSPH8,UCK2,UCK1,ZFYVE21,NSD3,CHKB,LYN,GGPS1,EXT2,VAV1,PDK2,MDM2,KMT5C,CD3EAP,CS,RPAP1,RPN2,SCYL3,SPSB3,PRPF19,RLIM,POLR2G,BIRC3,CGAS,PGGT1B,RNF25,METTL2A,PDHX,CLK3,FASTK,STK38,UHRF2,NCOA1,MAPK1,SMURF1,CBX4,NAT14,CMAS,CDS2,TRIP12,KLHL21,SHPRH,SCYL1,GNE,CDK11B,CSNK1A1,SCYL2,PIP4K2A,FASTKD3,HERC3,IRF4,GSTK1,FGFR3,GART,GRK2,KLHL20,KMT5A,ZDHHC13,POLR1B,PTGES3,FBL,RNF5,CAMK2G,B3GALT6,CSNK1G2,ELOVL5,ZDHHC18,HEMK1,PRKDC,METTL5,NADK2,RFFL,POLR3GL,PRMT2,MEN1,CDK11A,MAPK3,FBXO41,TRIM26,NEK1,GOLGA7,BIRC5,KBTBD7,DTX4,ACAT1,KMT2B,TAF12,PLOD3,RPS6KC1,UBE2C,SAT2,TERF1,HIPK3,GCSH |
| 1.202e-08 | -18.24 | negative regulation of cell cycle phase transition | biological process | GO:1901988 | 246 | 72 | 17256 | 2622 |
ZNF207,GPR132,CUL1,CCNB1,FANCI,PSMA6,PCNA,PSMD1,BABAM2,MDM2,CDKN1B,CTDSP2,CARM1,PLK1,PLK3,RBX1,PSMA8,BTG2,TAOK1,PSMB7,MRNIP,AURKB,BRCA1,SOX4,PSMB9,RPS27A,RBL1,PSMD8,PSMD3,E2F4,CHEK2,VPS4A,TFDP2,PSMC1,CLSPN,CDK2AP2,BABAM1,CENPF,BLM,CNOT11,PSMD9,CDC73,MAD2L2,CNOT3,RPA2,DTL,RFWD3,RB1,PSMD2,PTEN,CENPJ,FBXO7,BRD7,H2AFY,GTSE1,FBXL7,BCL2,CNOT6L,PRKDC,PSMA1,PRMT2,MEN1,PSMB3,PSMC4,CNOT9,TFDP1,PML,E2F1,PKD2,CNOT6,ZNF830,CDK2 |
| 1.206e-08 | -18.23 | GSE29614_CTRL_VS_DAY7_TIV_FLU_VACCINE_PBMC_DN | MSigDB lists | GSE29614_CTRL_VS_DAY7_TIV_FLU_VACCINE_PBMC_DN | 170 | 55 | 17377 | 2626 |
PPIB,FOXM1,CENPF,PTTG1,TPX2,NUF2,SDF2L1,CHAC2,CCNB1,NCAPG,SDHA,MYL6B,SPAG5,MAN1A1,FBXO5,ATG4A,DTL,OIP5,SUB1,KIF14,PHTF1,UBA5,SLC44A1,RPN2,OSTC,LMAN1,GINS1,VOPP1,POU2AF1,USO1,SEC61B,PBK,GNG7,MKI67,KIF15,MRPL12,RRM2,CDC6,NUSAP1,EAF2,SMC2,MCM2,SHCBP1,KIF11,TRAM2,HSPB11,DSN1,STT3A,CEP55,CBWD1,B4GALT3,CCNB2,GEN1,GLCCI1,S100PBP |
| 1.206e-08 | -18.23 | GO_POSITIVE_REGULATION_OF_CELL_CYCLE | MSigDB lists | GO_POSITIVE_REGULATION_OF_CELL_CYCLE | 314 | 86 | 17377 | 2626 |
CCNC,UBE2E2,CAST,SIRT2,ORC1,CCNL2,CCNB1,BECN1,PRKACA,APP,MDM2,PCNA,CDC42,KIF14,CDKN1B,CDC25B,CARM1,SRPK2,PLK3,PLK1,PSRC1,BRD4,PGGT1B,BTG2,CUL3,LRP5,NUSAP1,CDC6,AURKB,BRCA1,USP22,SOX4,RAB1A,RAD51C,RPS27A,E2F4,NSMCE2,UHRF2,XRCC3,ZNF268,TRIM32,CHEK2,TFDP2,GEN1,MIF,KIF3B,PKP4,PHB2,GORASP1,TCF3,KIF23,RACGAP1,CRLF3,RAB11A,CNOT3,FBXO5,TFAP4,CCNK,RB1,PTEN,CENPJ,PTPN11,H2AFY,GTSE1,CNOT6L,CITED2,TGFB1,ADAM17,RHOA,HMGN5,RBM38,GOLGA2,DUSP3,BIRC5,CDCA5,TFDP1,FAM83D,E2F1,PML,CNOT6,PKD2,CDK2,UBE2C,ESPL1,TERF1,CDKN2A |
| 1.226e-08 | -18.22 | KRIEG_HYPOXIA_NOT_VIA_KDM3A | MSigDB lists | KRIEG_HYPOXIA_NOT_VIA_KDM3A | 684 | 158 | 17377 | 2626 |
ZNF496,ADAM10,TMEM41B,ALKBH5,IKBIP,KCMF1,FANCI,KIFC1,ASAP2,NEK6,GLIS2,DPYSL2,IMPAD1,UPRT,TIPARP,MGAT5,TACC3,RYBP,ATG9A,LACTB,OGFR,LUC7L,ASF1B,DPYSL3,MAP3K4,ANKRD10,KIF18B,ZNF367,AXIN1,MLYCD,FBXL3,PFKP,GEMIN7,HJURP,KRBA1,SEC61G,TRIO,CENPF,RACGAP1,ITGB5,DTL,PDXP,MCM5,MBD2,DAPK1,GLTP,KNTC1,ALDH18A1,LPCAT1,CARS2,ELL2,CIC,TEX10,MFNG,MYBL2,RIT1,VKORC1,PTTG1IP,DAPK3,FAS,MASTL,SLCO4A1,SERTAD2,UAP1,CDCA5,NFIL3,SIAH2,SLC16A1,APOL2,CABLES1,NIPA1,N4BP2L2,EGLN1,ZNF296,FOXM1,FAM207A,CAST,SLC2A1,SLC39A13,MYH9,ORC1,BCL2L1,TCF19,KTN1,CRKL,PHC2,OIP5,PDK2,TNFAIP8,KDM2A,GRSF1,TP53BP2,RNF169,SAP30,ANKLE2,MKLN1,SLC26A6,NARF,PFKFB3,NUSAP1,PKMYT1,MEF2D,CADM1,VDAC1,USP36,ANKZF1,JAK1,CLK3,TAB2,MAFK,ARNTL,CEP55,FTSJ1,TICAM1,H3F3A,MAPK1,TUBB,CDS2,ZFP91,TCF3,CDT1,ARID5A,ARFIP2,KLF13,GMCL1,JMJD6,GGA2,ETS1,SLC25A36,PPP1R3B,ADD3,PDCD10,FJX1,PRC1,TMX1,MICAL3,RBM15B,PDLIM2,NIPAL3,AMPD2,TGFB1,TK1,TNFAIP3,TACC1,DENND4C,PRKAR1B,LDHA,EMP3,PACS1,KIF11,KLF6,ATAD2,POLE,BIRC5,IMPDH1,SRSF3,RBPJ,PGAM1 |
| 1.230e-08 | -18.21 | GSE27241_WT_CTRL_VS_DIGOXIN_TREATED_RORGT_KO_CD4_TCELL_IN_TH17_POLARIZING_CONDITIONS_DN | MSigDB lists | GSE27241_WT_CTRL_VS_DIGOXIN_TREATED_RORGT_KO_CD4_TCELL_IN_TH17_POLARIZING_CONDITIONS_DN | 157 | 52 | 17377 | 2626 |
MIF,CMAS,CDC40,ZCCHC9,RWDD1,SUCLG1,SRGN,SLC25A12,ASAH1,NHLRC3,GYG1,GGA2,AP3S1,PMVK,LYRM2,QSOX2,FERMT3,CDK5,SAR1A,MBD2,DAPK1,RNASEH2A,PIK3IP1,GPD1L,TMEM14C,SAP30L,S100A6,DRAM2,RNF5,LYPLA2,NIPSNAP1,LDHB,NOL12,CYTH1,KLF10,NCK1,MAPKAPK3,EMP3,TMEM147,TOMM40,KDM1B,TARS,PEX5,RWDD4,PPP3R1,ACADM,RRS1,FBXL3,CHMP7,SLC25A39,MRPL3,MYL12B |
| 1.256e-08 | -18.19 | DNA replication | biological process | GO:0006260 | 214 | 65 | 17256 | 2622 |
POLA2,PTMS,THOC1,RMI2,ORC1,SDE2,RPAIN,PCNA,DUT,RNASEH2A,TOP1MT,MCMBP,RFC3,KAT7,SLBP,RRM2,WDHD1,CDC6,BRCA1,MCM2,RFC2,POLG2,GINS4,PRIM1,CHAF1A,SUPT16H,TONSL,RBMS1,SSRP1,POLQ,DNAJC2,MCM10,CLSPN,TWNK,CHTF18,CDT1,DBF4,RRM1,DHX9,BLM,RMI1,NEXMIF,WRNIP1,RPA2,DTL,RFWD3,MCM5,TIMELESS,ORC3,GINS1,NASP,PRIM2,POLK,HELB,WDR18,TOP3A,RPA1,UPF1,NAP1L1,POLE,DTD1,RBBP4,ZNF830,CDK2,PURA |
| 1.263e-08 | -18.19 | SNRNP27 (small nuclear ribonucleoprotein U4/U6.U5 subunit 27) | protein interactions | 11017 | 112 | 43 | 17029 | 2761 |
RECQL,MTX3,CHERP,USP39,ARGLU1,HDGFL2,PMVK,GTF2F1,MCTS1,PDCD10,CTNNBL1,PPP1R8,PIN1,ARF5,TXLNA,PTPN11,NAA50,RPRD1B,ILKAP,CGGBP1,LUC7L2,SRPK2,USO1,RPRD1A,MAPRE2,RBM42,HMGN5,PBK,ADSL,ARMT1,PRPF3,EIF2A,PKM,PICALM,MAPK3,SEC23IP,HINT1,DUSP3,DHX16,TPP2,PRPF4,SNRPG,IFI16 |
| 1.263e-08 | -18.19 | DDX18 (DEAD-box helicase 18) | protein interactions | 8886 | 112 | 43 | 17029 | 2761 |
BCCIP,NIFK,DDX47,RPS2,NOP2,RRP15,KMT2E,SUZ12,CUL1,EBNA1BP2,BRIX1,APP,LMNA,RPL11,KRR1,DDX56,MTA1,NOC2L,RPF2,POLR1B,FBL,DDX24,ABCF2,GTPBP4,CUL3,RPL8,GAR1,DHX15,CAND1,RPL36,NSA2,UTP20,C1orf131,HNRNPR,DGCR8,NIP7,TBL3,RPS14,DDX5,SRSF3,RRS1,IFI16,BYSL |
| 1.280e-08 | -18.17 | GSE32986_UNSTIM_VS_CURDLAN_LOWDOSE_STIM_DC_UP | MSigDB lists | GSE32986_UNSTIM_VS_CURDLAN_LOWDOSE_STIM_DC_UP | 188 | 59 | 17377 | 2626 |
BCCIP,USP7,HSPH1,RWDD1,URB2,SRGN,UCK2,NKRF,SLC35B1,SND1,SNRPD3,BRIX1,SAC3D1,FBRS,LYAR,ERH,SUB1,HOMER1,PSMA6,STRBP,ATP2A2,PIN1,RBM34,SEPT11,YIF1B,NUP153,PPA1,TMBIM1,MRPL32,S100A6,TIMM50,ABCC1,FDFT1,SRSF10,PLK3,TGFB1,B3GALT6,COPS8,UBQLN4,HEMK1,NOL8,SMU1,DCTD,BMS1,ODC1,GFER,ABCF1,EML4,USP36,SLCO4A1,SNAP23,GADD45B,RGL1,ZNF598,LRP8,NMD3,RAB3IL1,DDX42,FUBP1 |
| 1.280e-08 | -18.17 | GSE36392_TYPE_2_MYELOID_VS_NEUTROPHIL_IL25_TREATED_LUNG_DN | MSigDB lists | GSE36392_TYPE_2_MYELOID_VS_NEUTROPHIL_IL25_TREATED_LUNG_DN | 188 | 59 | 17377 | 2626 |
NOP2,PHF23,SEC61G,MAGED1,EIF3D,CENPF,TRIO,CERK,GTF3A,TBC1D13,AP1B1,SYNRG,MYEF2,RAD23A,DDRGK1,RPL17,IL6ST,ETV6,FAM89B,ORAI1,RPL19,AHCY,CYC1,ACAD8,PACS2,CARM1,FYTTD1,GTF3C6,RPL35,HEMK1,SEPT9,KAT2A,IDH3A,EMB,VHL,MRS2,PSMB7,GORASP2,TOMM40,ICMT,STOML2,NAP1L1,ITPRIPL1,VPS26B,PDRG1,C1orf109,PPM1G,NFIL3,ZDHHC7,FKBP5,PIEZO1,NDUFS5,PLOD3,PPP5C,REEP4,PGAM1,PSMC1,PFKP,FAM72A |
| 1.280e-08 | -18.17 | GSE17721_PAM3CSK4_VS_CPG_6H_BMDC_UP | MSigDB lists | GSE17721_PAM3CSK4_VS_CPG_6H_BMDC_UP | 188 | 59 | 17377 | 2626 |
SEPHS2,LZTR1,HJURP,NOP2,PHB2,MANBA,WDR13,RPS6KA1,SRSF6,MRPS26,SMC6,B4GALT1,CDC42SE2,EIF2AK4,PRPF39,TMEM165,SAC3D1,EBP,FERMT3,PSMD2,NAPG,NUP210,GATC,SNX18,PHTF1,RNF26,ATF2,LRRC59,KDELR1,ELOF1,USP34,SRPK2,AMPD2,CCT2,CLCN3,LARS,PPP1R18,TRIM8,PBXIP1,ADSL,CDC6,SMC2,PLEC,PRKRA,MBD3,FANCE,TSR2,MFN2,UTP20,TMEM184C,TTC13,ETS2,FAM122A,CTSA,ACADM,GAS2,YY1,ATP6V0E1,SNAPIN |
| 1.280e-08 | -18.17 | GSE18203_CTRL_VS_INTRATUMORAL_CPG_INJ_MC38_TUMOR_DN | MSigDB lists | GSE18203_CTRL_VS_INTRATUMORAL_CPG_INJ_MC38_TUMOR_DN | 188 | 59 | 17377 | 2626 |
PDCD6IP,PLXNC1,ZFP91,TPX2,RRM1,NCAPG,STMN1,GLRX3,LCLAT1,REEP5,PRNP,MOAP1,CDKN2C,LYAR,RB1,DECR1,RPN1,PCNA,CCNA2,EIF2S2,TIMM23,MCM5,PRC1,MDFIC,CLDND1,CDC25B,MRPL11,TMBIM1,S100A6,PDPK1,POU2AF1,CCT2,CYFIP1,ERMP1,NQO2,MKI67,RRM2,NUSAP1,ODC1,ASF1B,PRDX1,RPA1,PRIM1,GLOD4,IDE,GALNT2,MID1IP1,GADD45B,DBI,CDCA5,RWDD4,HMGB2,KPNA2,SASS6,PGAM1,CCNB2,UBE2C,TSPAN5,VPS29 |
| 1.284e-08 | -18.17 | CHANG_CORE_SERUM_RESPONSE_UP | MSigDB lists | CHANG_CORE_SERUM_RESPONSE_UP | 197 | 61 | 17377 | 2626 |
WSB2,SRM,BCCIP,MAPRE1,H2AFZ,CKLF,UQCR10,RHOC,PDAP1,EBNA1BP2,C19orf48,GLRX3,POLR3K,PNO1,MCTS1,KRR1,HNRNPA2B1,LYAR,FARSA,RPN1,PA2G4,PSMD2,SAR1A,CENPJ,DBNDD1,DUT,NUP107,FAM89B,TRA2B,MYBL1,NUP85,RFC3,ERLIN1,SNRPB,MRPL12,MYBL2,EZR,WDHD1,NLN,EIF2AK1,SMC2,NUTF2,TOMM40,VDAC1,GSTCD,SLC25A5,SNRPA,HMGN2,FBXO41,HSPB11,CDCA4,UAP1,HNRNPR,DCK,CORO1C,SLC16A1,NCLN,COPS6,CDK2,PFKP,IPO4 |
| 1.295e-08 | -18.16 | UPF1 (UPF1, RNA helicase and ATPase) | protein interactions | 5976 | 164 | 56 | 17029 | 2761 |
NADSYN1,NIFK,CYLD,EWSR1,IVNS1ABP,SUZ12,GSPT2,RBM8A,SMARCA4,PARN,EDC3,RPL11,ABHD16A,CEP104,EIF2S2,STRBP,EIF4A3,DCP1A,UPF2,TARDBP,RBM3,TTC4,ZC3H3,PABPC1,TMX1,DCTN1,CDC37,CDC5L,PPAN,STAU1,SNRPB,MEMO1,RPL6,RNPS1,CUL3,LSM8,SLBP,BRCA1,PCGF1,POLR2A,EIF3A,CAND1,NSA2,SYNCRIP,HNRNPR,DGCR8,H2AFX,DDX5,FUS,RUVBL2,SMG9,SNRNP70,CDK2,OAZ1,ZC3HAV1,IFI16 |
| 1.296e-08 | -18.16 | GO_MITOCHONDRIAL_PROTEIN_COMPLEX | MSigDB lists | GO_MITOCHONDRIAL_PROTEIN_COMPLEX | 107 | 40 | 17377 | 2626 |
NDUFA5,NDUFV2,TOMM20,IMMT,NDUFS1,NDUFB6,UQCR10,NDUFA4,COX4I1,SDHA,PARK7,NDUFS7,NDUFS4,PDK2,NDUFV1,NDUFA2,NDUFB4,TIMM23,NDUFB9,NDUFS8,APOOL,NDUFA3,TIMM50,PPIF,TIMM8B,NDUFA7,NDUFB1,TOMM40,FOXRED1,CHCHD6,ANKZF1,SDHB,CHCHD3,TIMM13,TIMM17A,TOMM6,NDUFA11,COX8A,COX5A,NDUFS5 |
| 1.296e-08 | -18.16 | REACTOME_TCA_CYCLE_AND_RESPIRATORY_ELECTRON_TRANSPORT | MSigDB lists | REACTOME_TCA_CYCLE_AND_RESPIRATORY_ELECTRON_TRANSPORT | 103 | 39 | 17377 | 2626 |
COX5B,NDUFA5,NDUFV2,NDUFS1,NDUFB6,SUCLG1,MDH2,NDUFA4,COX4I1,CYCS,SDHA,NDUFS7,NDUFS4,PDK2,NDUFV1,NDUFA2,NDUFB4,CS,SUCLG2,NDUFB9,NDUFS8,CYC1,NDUFA3,LDHB,IDH3A,LDHA,OGDH,NDUFA7,NDUFB1,PDHX,SDHB,NDUFA11,COX7A2L,COX8A,COX5A,SLC16A1,UQCRH,NDUFS5,IDH3B |
| 1.299e-08 | -18.16 | GO_NUCLEAR_ENVELOPE_ORGANIZATION | MSigDB lists | GO_NUCLEAR_ENVELOPE_ORGANIZATION | 76 | 32 | 17377 | 2626 |
CHMP2A,NUP188,RAE1,TOR1AIP1,NUP54,CCNB1,NUP205,LMNA,UBXN2A,NUP210,NEK6,BANF1,NUP107,NSFL1C,TARDBP,NUP153,NUP85,SEH1L,PLK1,ANKLE2,NUP155,TOR1AIP2,PPP2CA,LEMD2,UBXN2B,OSBPL8,CHMP4B,NUP62,CCNB2,CHMP7,REEP4,AAAS |
| 1.321e-08 | -18.14 | EIF3A (eukaryotic translation initiation factor 3 subunit A) | protein interactions | 8661 | 116 | 44 | 17029 | 2761 |
UNK,CYLD,GPBP1L1,EIF3D,MYH9,EIF1B,BZW2,PAIP1,WDR48,WWP2,MEX3C,AHSA1,ZNF746,UBA5,TARDBP,NAP1L4,ATP6V0D1,SRPK2,STAU1,EIF3L,ABCF2,HNRNPF,RPS10,KRAS,BRCA1,TOMM40,EIF4H,KIF11,EIF4G2,RPS9,EIF3G,EIF3H,EIF3K,UPF1,TFE3,RPLP1,YWHAZ,XRCC3,FAU,CDK2,SMURF1,CD81,RPS26,RNF139 |
| 1.338e-08 | -18.13 | response to ionizing radiation | biological process | GO:0010212 | 148 | 50 | 17256 | 2622 |
KARS,DNMT3A,EYA1,PRKAA1,BABAM1,TMEM109,RRM1,BCL2L1,IKBIP,BLM,MAPK14,RFWD3,BABAM2,MDM2,TIGAR,INTS7,MTA1,TANK,XRCC2,NABP2,NABP1,MSH2,DNM2,BCL2,SPIDR,EEF1D,BAK1,TGFB1,ERCC1,NET1,PRKDC,RAD51AP1,MRNIP,DCLRE1C,BRCA1,ELK1,MEN1,RHOB,XRCC5,RAD51C,H2AFX,PML,AEN,STK11,XRCC3,CHEK2,XRCC4,HRAS,RAD51D,IFI16 |
| 1.345e-08 | -18.12 | ribosome | cellular component | GO:0005840 | 238 | 69 | 18223 | 2701 |
RPLP2,MRPS15,MRPL39,MRPL19,RPL23A,RPL11,MRPL50,MRPS27,MRPL34,MRPL32,MRPL57,RPL29,RPL35,NCK1,MRPL43,MRPL12,RPL38,NDUFA7,MRPS14,RPS9,SERP1,RPSA,RPL37,GEMIN5,MRPL2,DAP3,MRPL55,RPS27A,RPS14,CHCHD1,MRPL27,EIF2D,RPLP1,MRPL13,RPS26,RPS15,MRPL9,RPS2,MRPL42,MRPS2,MRPS26,DHX9,RPL15,EIF2AK4,MCTS1,RPL17,RRBP1,LTN1,MRPL54,RBM3,RPL19,MRPL48,MRPL40,MRPL11,MRPL21,NSUN4,RPL22L1,RPS10,RPL8,RPL6,MRPS10,RPS24,MRPL16,EIF2A,RPL27A,ABCF1,RPL36,RPL32,MRPL3 |
| 1.347e-08 | -18.12 | GNL3 (G protein nucleolar 3) | protein interactions | 26354 | 86 | 36 | 17029 | 2761 |
BCCIP,NIFK,TRIP12,NOP2,RPL15,CUL1,EBNA1BP2,RPL11,KRR1,MDM2,EIF4A3,ZNF746,CDKN1B,RPL19,TARDBP,FBL,STAT3,FTSJ3,PPAN,DDX24,TEX10,RNPS1,CUL3,RPL6,RPS24,DIDO1,MPG,DOT1L,CAND1,PPP2R5A,RPS14,RRS1,RBBP4,TERF1,CDKN2A,IFI16 |
| 1.366e-08 | -18.11 | RPL30 (ribosomal protein L30) | protein interactions | 6156 | 215 | 68 | 17029 | 2761 |
COX15,CYLD,NOP2,RPLP2,CUL1,EBNA1BP2,BRIX1,SDHA,APP,RPL11,RPL23A,PA2G4,RPF2,FTSJ3,RPL35,VHL,RPL38,CUL3,BRCA1,PRKRA,MCM2,VDAC1,MAK16,RPS9,RPSA,RPL37,NSA2,NIP7,RPS14,RPLP1,ARRB2,RPS26,CCDC137,NIFK,RPS15,UNK,RPS2,RPL15,TTF1,LYAR,DDX56,RBM34,RPL19,DDX31,POLR1B,MAP3K14,NSUN4,HNRNPM,ZNF189,HP1BP3,STAU1,DDX24,ZNF512,RPL8,GTPBP4,ZNF574,RPL6,RPS10,RPS24,LLPH,RPL27A,PHF6,CAND1,RPL36,RPL32,CDK2,GPATCH4,ZC3HAV1 |
| 1.402e-08 | -18.08 | MYO1C (myosin IC) | protein interactions | 4641 | 181 | 60 | 17029 | 2761 |
COX15,ADD1,PPP1R12A,CHERP,SUZ12,SF3B1,MYH9,HDGFL2,TWF2,SAFB2,JMY,LMNA,GTF2F1,SF3B2,RBM17,RPA2,RRN3,UBE2Q2,SHC1,MEX3C,NEK6,PTEN,NSRP1,MCM5,ZNF746,POLR1B,CCAR1,CFL1,MYO5A,SPTAN1,TIMM8B,AGGF1,WDR1,TRIR,OXR1,ILF3,CAPZA2,SEPT7,ANLN,STYXL1,KIF11,RPA1,CCDC127,CHCHD3,INF2,TIMM13,MRPL55,HNRNPR,TIMM29,CORO1C,U2SURP,MED15,MYO18A,BAZ1B,USP20,IMPDH1,HMGB2,CDK2,ARRB2,CDKN2A |
| 1.402e-08 | -18.08 | RPL10A (ribosomal protein L10a) | protein interactions | 4736 | 181 | 60 | 17029 | 2761 |
COX15,RPS2,CYLD,NOP2,RPLP2,MECP2,DHX8,RPL15,CUL1,BRIX1,RPL11,RPL23A,MDM2,PTEN,RPL17,HUWE1,RBM34,ZNF746,RPL19,TARDBP,TFG,ZC3H3,PABPC1,HNRNPM,FYTTD1,RPL29,RPL35,VHL,NOL8,RPS10,RPL6,GTPBP4,RNPS1,CUL3,ILF3,RPL8,RPL38,RPS24,BRCA1,MCM2,RPL27A,SLC25A5,RPS9,RPSA,CENPU,RPL36,CAND1,NAP1L1,RPL32,RAD18,DGCR8,RPS27A,RPS14,RPLP1,ACTB,RRS1,CDK2,RPS26,ZC3HAV1,GPATCH4 |
| 1.406e-08 | -18.08 | PPP1CC (protein phosphatase 1 catalytic subunit gamma) | protein interactions | 5501 | 295 | 86 | 17029 | 2761 |
MAX,PPP1R15B,RAF1,TOR1AIP1,MYH9,CUL1,NUF2,BCL2L1,CCNB1,SAFB2,PPP1R16B,STAM,APP,HNRNPA2B1,PCNA,DPYSL2,NUP153,TP53BP2,PLCL2,RBM12B,SPATC1L,SP3,CCT2,SHOC2,DEAF1,SGCE,PPP1R18,MAP4K4,MKI67,ELP4,WDR82,CDCA2,ERBIN,TRIM28,HSPA4,DSN1,PDRG1,UBXN2B,CORO1C,PQBP1,ACTB,MAPK1,TUBB,PPP1R2,RRM1,ATP5F1B,EIF2AK4,PMF1,CSNK1A1,LMNA,PPP1R3B,RPA2,STARD9,RB1,PPP1R8,ZNF326,BCL2,ACAD8,RPAP3,STAU1,FTL,PPP1R9B,CYFIP1,HMGN1,ILF3,KCTD20,EIF2A,LRRC1,POLR2A,NMT2,TWISTNB,RPA1,CTSL,INF2,KIF18A,GOLGA7,BIRC5,RBMX,HNRNPH3,SIAH2,PPP1R11,YWHAZ,BTBD10,CDK2,NRBP1,CDKN2A |
| 1.417e-08 | -18.07 | positive regulation of catabolic process | biological process | GO:0009896 | 397 | 103 | 17256 | 2622 |
ATXN3,TSC2,SUMO2,CSNK2A1,YTHDF3,SIRT2,UBQLN2,BECN1,BCAP31,ANKIB1,TRIM65,PARK7,FBXO22,EPM2A,USP5,RAD23A,MDM2,RALB,METTL14,CDKN1B,RNF19A,TIPARP,CDC37,PLK1,PLK3,TRIM8,POLR2G,RBX1,AKT2,RAB7A,BTG2,PFKFB3,EZR,EDEM2,OPTN,ABHD5,IDE,HNRNPR,AXIN1,SOCS4,ADAM9,TICAM1,STK11,TRIM32,CLU,DVL1,ROCK1,SMURF1,PSMC1,OAZ1,CSNK1D,USP13,SVIP,SCOC,GGA1,AGO2,PRKAA1,NKD2,EIF2AK4,CSNK1A1,PSEN1,METTL3,PIP4K2A,WWP2,DDRGK1,DTL,PTEN,FBXO7,DAPK1,CNOT6L,LRSAM1,LPCAT1,TPCN1,PHKG2,PABPC1,SOCS5,ATP5IF1,LONRF3,TNFAIP3,GBA,PIP4K2C,ADRB2,PTTG1IP,SH3GLB1,MAPK3,MFN2,TFEB,PSMC4,HSPA1B,TSC1,KEAP1,UPF1,HSPBP1,NSF,OAZ2,KHSRP,CD81,RNF14,TOB1,RNF139,DDB1,ZC3HAV1,RNF114 |
| 1.418e-08 | -18.07 | GSE339_EX_VIVO_VS_IN_CULTURE_CD4CD8DN_DC_UP | MSigDB lists | GSE339_EX_VIVO_VS_IN_CULTURE_CD4CD8DN_DC_UP | 184 | 58 | 17377 | 2626 |
SEPHS2,IER2,NSMCE4A,TRIM11,WDR13,VAV2,ANK3,MOGS,TIA1,UCK1,COX4I1,KIF2C,SND1,NFATC3,INTS7,TBC1D22A,ARHGEF1,XPA,ANP32A,FBXW2,SUCLG2,ABCD1,PRADC1,SPTSSA,NDUFA3,DNMT1,SLC35A1,GM2A,TMX1,ACSL5,PPIF,KDM3B,PTPN18,PPP1R18,RNASEH2C,MTA2,PRKDC,PPP1R21,METTL5,NUSAP1,SMC2,ARID1A,ANLN,KRTCAP2,VKORC1,PSMB9,CBFB,RHOB,RBM38,CHCHD3,CAT,HHEX,WAS,DTD1,PSAP,RGL1,VPS4A,CCNB2 |
| 1.418e-08 | -18.07 | GSE22432_MULTIPOTENT_VS_COMMON_DC_PROGENITOR_UNTREATED_DN | MSigDB lists | GSE22432_MULTIPOTENT_VS_COMMON_DC_PROGENITOR_UNTREATED_DN | 184 | 58 | 17377 | 2626 |
HIVEP3,PIGM,PHB2,DBF4,C19orf25,CHAC2,C19orf48,BZW2,ERH,DDX56,UBXN2A,RRN3,SUB1,PCNA,NOL11,NDUFB4,PIN1,NUP107,C8orf59,FBL,TMBIM1,SEH1L,NUDC,CSTF1,PRPF19,RBM15B,FDFT1,TELO2,ATP13A1,GUK1,HARS,UTP15,CAMSAP1,KRAS,ABHD11,USP22,CBFB,GFER,GEMIN5,TPD52L2,CDC16,MRPL55,PFDN4,LSM6,NIP7,TBL3,TFE3,NSMCE2,PIAS2,RWDD4,PRMT7,FAM126A,SRSF3,RUVBL2,NAA20,PTDSS1,PURA,C7orf26 |
| 1.418e-08 | -18.07 | GSE25088_WT_VS_STAT6_KO_MACROPHAGE_IL4_STIM_DN | MSigDB lists | GSE25088_WT_VS_STAT6_KO_MACROPHAGE_IL4_STIM_DN | 184 | 58 | 17377 | 2626 |
POLA2,TXN,HJURP,PTTG1,CENPF,SMARCA4,RACGAP1,GTF3A,CCNB1,NCAPG,FZD6,FANCI,SPAG5,DTL,OIP5,FANCL,PCNA,CLIC4,ASAP2,PSMA6,SSBP3,KIF14,DAPK1,PRC1,H2AFY,YBX1,MAST2,DNMT1,GINS1,SLC39A9,ELOVL5,TK1,RFC3,NASP,ASPM,PRKDC,RAD51AP1,MKI67,DNAJC9,RRM2,NUSAP1,ASB13,KIF11,CHAF1A,HMGN2,CDCA4,POLE,CEP55,RPLP1,H2AFX,SLC16A1,HMGB2,KPNA2,RUFY3,NUDT11,CCNB2,ESPL1,SMARCD1 |
| 1.424e-08 | -18.07 | RPS24 (ribosomal protein S24) | protein interactions | 6229 | 148 | 52 | 17029 | 2761 |
RPS15,NIFK,RPS2,CYLD,NUP188,PNISR,RPLP2,NDUFAF2,DHX9,MOGS,RPL15,CUL1,PNO1,RPL11,RPL23A,EIF4A3,RPL17,HUWE1,ZNF746,MSH2,RPL19,TARDBP,FBL,HNRNPM,HP1BP3,PRPF19,SPTAN1,RPL29,RPL35,SF3B6,RPS10,RPL6,CUL3,ILF3,RPL8,TUFM,BRCA1,EIF2A,SLC25A5,STK17B,RPS9,RPSA,CAND1,RPL36,RPS27A,RPS14,RPLP1,RRS1,FAU,CDK2,SMURF1,RPS26 |
| 1.425e-08 | -18.07 | NOTCH1 (notch 1) | protein interactions | 4851 | 237 | 73 | 17029 | 2761 |
TCF12,USP7,SART1,ADAM10,MAGED1,XIAP,DHX8,SMARCA4,DAZAP2,APP,VAV1,MDM2,ANAPC7,MOB1A,PRPF19,POU2AF1,GOPC,RAB7A,LRBA,CUL3,LNX2,PBRM1,CDC23,TRIM28,DHX15,DDX17,PPP2CA,KIF2A,WDR11,STK38,TRIM32,ROCK1,USP11,MAPK1,NUMB,LRCH1,PRKAA1,EPN1,TOP2B,NOTCH2,PSEN1,SRRT,POFUT1,ERH,RB1,SMC3,PTEN,MCM5,ARHGEF2,MAML1,PPP6R1,ADAM17,RHOA,TRAPPC9,KAT2A,HMGN5,PRKDC,MFNG,ARMC8,CCT8,RMC1,CAND1,HGS,CDC27,GOLGA2,CCZ1B,DTX4,RBPJ,PPP6R3,YY1,ZMIZ1,RBBP4,IFI16 |
| 1.430e-08 | -18.06 | GSE22601_IMMATURE_CD4_SINGLE_POSITIVE_VS_CD4_SINGLE_POSITIVE_THYMOCYTE_UP | MSigDB lists | GSE22601_IMMATURE_CD4_SINGLE_POSITIVE_VS_CD4_SINGLE_POSITIVE_THYMOCYTE_UP | 193 | 60 | 17377 | 2626 |
BCCIP,ZNF207,PRPF38B,GPR132,SYS1,SCAMP3,RPS6KA1,PIGQ,SRSF6,VPS45,TIA1,ARF1,METTL3,EXT2,APP,ERH,ATP2A2,ATG3,PPME1,ETV6,EI24,ANXA5,CLDND1,CORO1A,CNN2,TALDO1,PDIA6,S100A6,POU2AF1,GTF3C6,RBX1,CIC,AKT2,DHX29,SELPLG,MRS2,NARF,GBA,CRNKL1,DNAJA1,TMEM147,BICD2,ESYT1,CDC23,NDRG3,PICALM,SMAP2,CYB5A,ECH1,HSPA1B,SLCO4A1,MID1IP1,PPP2R5A,CSK,CHD3,CEP55,STAT1,SSNA1,KPNA2,TRAF5 |
| 1.434e-08 | -18.06 | rRNA processing | biological process | GO:0006364 | 261 | 75 | 17256 | 2622 |
SART1,DDX47,RPLP2,NOP2,EBNA1BP2,RPL23A,KRR1,RPL11,UTP25,PA2G4,NOL11,EIF4A3,UTP18,EXOSC1,RPF2,UTP4,FTSJ3,MRM2,RPP25,RPL29,RPL35,EXOSC6,NOL8,RPL38,UTP3,GAR1,RPS9,MAK16,RPSA,DDX17,RPL37,NSA2,RPS27A,LSM6,TBL3,RPS14,RPLP1,RNASEL,RRS1,PDCD11,RPS26,CSNK1D,RPS15,RPS2,RRP15,RPL15,PNO1,RRP36,KRI1,LYAR,DDX56,EXOSC7,RPL17,RPL19,GEMIN4,FBL,NSUN4,MRM3,TEX10,WDR18,RPL6,RPL8,UTP15,RPS10,GTPBP4,RPS24,EXOSC9,BMS1,RPL27A,TSR2,RPL36,UTP20,RPL32,BYSL,DDX52 |
| 1.439e-08 | -18.06 | GSE7568_IL4_TGFB_DEXAMETHASONE_VS_IL4_TGFB_TREATED_MACROPHAGE_UP | MSigDB lists | GSE7568_IL4_TGFB_DEXAMETHASONE_VS_IL4_TGFB_TREATED_MACROPHAGE_UP | 162 | 53 | 17377 | 2626 |
NUP188,TMEM184B,TRMT6,ALKBH5,TMEM97,SND1,PNO1,FASTKD3,ERH,SLC31A1,NEK6,IARS,TIMM23,RBM34,AHSA1,GRSF1,EFTUD2,TPST1,NSFL1C,YBX1,MCPH1,SLC12A2,HPDL,ERLIN1,AMD1,PPIE,POLR2D,UTP15,DCTD,UTP3,PPWD1,VDAC1,DDX39A,GUF1,RFC2,CCT8,PDHX,EIF3G,PSMC4,XRCC5,AKAP1,NIP7,PRDX3,PSMD3,PPM1G,RWDD4,WIPI2,KLHDC4,NAA20,CD81,GCSH,PFKP,FUBP1 |
| 1.441e-08 | -18.06 | TADA2A (transcriptional adaptor 2A) | protein interactions | 6871 | 144 | 51 | 17029 | 2761 |
CDC40,LUZP1,XAB2,TCF3,WDTC1,WDR5,PPP1R16B,LYN,MYEF2,MED8,SRSF4,AKAP8,TTC9C,TRA2B,MCPH1,MTX2,HNRNPM,MED22,CDC5L,PRPF19,EIF3L,KAT2A,PSPC1,HNRNPF,RNPS1,ILF3,USP22,SRSF5,LUC7L,TRIM28,MARK2,SNRPA,DHX15,EIF3H,POLR2A,SRSF1,DDX17,MBIP,HGS,DHX16,MFAP1,LUC7L3,CDCA7L,MED15,C1orf109,DDX5,KPNA2,SRSF3,SGF29,DDB1,ZNF564 |
| 1.446e-08 | -18.05 | TYMS (thymidylate synthetase) | protein interactions | 7298 | 55 | 27 | 17029 | 2761 |
EIF5A,UNK,UBQLN4,TXN,WDR1,UFC1,ZFYVE21,ADSL,STMN1,MAPK14,PDCD6,DCK,E2F4,DUT,ATIC,E2F1,UPF2,ZRANB2,AHCYL1,ATP6V1C1,IGBP1,PGAM1,WDR45B,UBE2C,UBE2M,POC5,SSSCA1 |
| 1.454e-08 | -18.05 | RANBP2 (RAN binding protein 2) | protein interactions | 5903 | 136 | 49 | 17029 | 2761 |
KIF3B,CHMP2A,IER2,SUZ12,SUMO2,DHX9,CDCA8,CUL1,TOP2B,UBE2I,CDC73,LMNA,KIF5B,MDM2,PSMD1,SP100,ZNF746,EFTUD2,NUP107,CRY2,KIFAP3,NUP153,PTGES3,NUP85,SENP1,SEH1L,HNRNPM,CDC5L,SNRNP200,PRKDC,HNRNPF,SMU1,NUSAP1,RANGAP1,NFATC2,ADRB2,MCM2,MATR3,DHX15,DDX17,WAS,KPNA1,RPS14,PML,NUP62,KPNA2,RRS1,NUP58,TUBB |
| 1.520e-08 | -18.00 | DNA damage checkpoint | biological process | GO:0000077 | 140 | 48 | 17256 | 2622 |
CLSPN,BABAM1,EIF2AK4,CCNB1,BLM,CNOT11,MAPK14,FANCI,CNOT3,DTL,RFWD3,RPA2,BABAM2,MDM2,PCNA,INTS7,CENPJ,PTPN11,MSH2,CDKN1B,GTSE1,CEP63,CNOT6L,ATF2,CARM1,CDC5L,PRPF19,PLK3,PLK1,PRKDC,BTG2,TAOK1,MRNIP,BRCA1,SOX4,DOT1L,CNOT9,RPS27A,E2F4,TFDP1,H2AFX,E2F1,PML,CNOT6,CHEK2,TFDP2,ZNF830,CDK2 |
| 1.548e-08 | -17.98 | FOXQ1 (forkhead box Q1) | protein interactions | 94234 | 105 | 41 | 17029 | 2761 |
ZBTB10,COPA,FAM207A,SF3B1,HNRNPUL2,NKRF,UBE4A,NUP205,SF3B2,KIF5B,NDUFV1,IARS,NUP107,ZNF326,NOC2L,KIF22,ANAPC7,ORC3,ANKHD1,NUP85,SMC4,SRPK2,LARS,USO1,SNRNP200,DDX24,BTAF1,SUGP2,WDR18,TEX10,RANGAP1,SMC2,FXR1,DDX39A,SYMPK,ZFR,ZMYM3,POLE,CDC27,CCDC86,NSF |
| 1.548e-08 | -17.98 | ARF1 (ADP ribosylation factor 1) | protein interactions | 375 | 105 | 41 | 17029 | 2761 |
UNK,COX15,RAB11B,GGA1,COPE,ARFIP2,USP39,RAB6A,ARF1,AP1B1,GGA2,DUSP22,RAB11A,PARK7,CDC73,WWP2,PRNP,ASAP2,SAR1A,HUWE1,AP3S2,ARF5,AHSA1,ATF2,TMED2,KDELR1,LDHB,STAU1,CYTH1,PTPN18,NOA1,LDHA,TUFM,VDAC1,RAB1A,AP4E1,RAB5B,ARF4,TMED10,ACADM,CDK2 |
| 1.590e-08 | -17.96 | GSE2770_UNTREATED_VS_ACT_CD4_TCELL_2H_DN | MSigDB lists | GSE2770_UNTREATED_VS_ACT_CD4_TCELL_2H_DN | 189 | 59 | 17377 | 2626 |
MIF,SRM,SARNP,EWSR1,MRPS2,MRPL39,USP39,C2orf49,PCBP1,PARK7,TUBGCP2,RAD23A,LRRC14,ZBTB45,DNAAF2,IMPAD1,ZNF746,EFTUD2,TTC9C,FEM1B,PARL,SUCLG2,AHCY,LMAN1,TFG,TTLL12,TMBIM1,HNRNPM,ACSL5,FYTTD1,CELSR2,LAP3,DENND4C,METTL5,PPIE,ARHGEF12,MAP7D1,PPWD1,EIF4G2,GEMIN5,KEAP1,TTLL4,TONSL,TOMM6,E2F4,PSMD3,LY75,MRFAP1L1,VPS4A,SMAD1,NDE1,E2F2,PDSS2,TERF1,CBX4,FAM83G,DDB1,FAF1,HDAC2 |
| 1.590e-08 | -17.96 | GSE22033_UNTREATED_VS_MRL24_TREATED_MEF_UP | MSigDB lists | GSE22033_UNTREATED_VS_MRL24_TREATED_MEF_UP | 189 | 59 | 17377 | 2626 |
PRKAB1,MAGEH1,PKP4,SUCLG1,ZNF768,TKT,TPX2,CDCA8,STARD7,SECISBP2,BCL2L1,FAM136A,MAPK14,GGPS1,IL21R,RAB11A,GNB2,RSAD1,HDDC2,SNRNP25,MTMR4,AHSA1,ATIC,SSBP3,ANP32A,MYBL1,GPD1L,CAMK2G,DNAL4,PRPF19,EIF5A,TIMM8B,DEAF1,LARS,MAPKAPK3,E2F3,SEPT8,SLBP,SLC25A22,UBE4B,PPFIA3,BICD2,RHOT1,HAGH,ARMC8,KIF11,SYMPK,RBM38,STOML2,TIMM13,DSN1,BIRC5,PTER,IARS2,AP1S1,CCNB2,MZT2B,CBX4,HDAC2 |
| 1.590e-08 | -17.96 | GSE17721_CTRL_VS_GARDIQUIMOD_4H_BMDC_UP | MSigDB lists | GSE17721_CTRL_VS_GARDIQUIMOD_4H_BMDC_UP | 189 | 59 | 17377 | 2626 |
NAT9,ADD1,UGP2,MRPS15,GNPDA1,MRI1,CUTA,STRN4,CDCA3,AGPAT3,SEC16A,C19orf48,LCLAT1,HMG20A,XPR1,CHKA,C14orf119,SF3B2,DTL,RPA2,GOLM1,GATC,STRBP,CWC27,MRPL34,ATP6V0A2,TTC4,AQR,CPSF4,MYO5A,PDLIM2,ADCY7,GINS1,TMEM115,GALC,MAP4K4,FBXO9,ANAPC2,GALK2,PRPF3,MEF2D,TXNL4A,CLNS1A,BTBD1,TFEB,NEK1,MFAP1,LUC7L3,ATE1,CRCP,USP20,PDXK,RBBP4,CDK2,PTDSS1,AP2S1,CBX4,GPATCH4,NUDT3 |
| 1.590e-08 | -17.96 | HOLLMANN_APOPTOSIS_VIA_CD40_UP | MSigDB lists | HOLLMANN_APOPTOSIS_VIA_CD40_UP | 189 | 59 | 17377 | 2626 |
TMEM106C,NCOR2,HSPH1,MAGEH1,ENSA,XPO7,ATP6V1B2,PARN,CPNE3,CREM,GTF2F1,DST,VAV1,DPYSL2,MBD2,DUT,MRPL34,TIMELESS,MAST2,CYB5R1,TCEA1,CLTB,MYBL1,SGCB,PPP6R1,GM2A,SMC4,PDLIM2,USP34,LAP3,TACC1,NQO2,KIAA0930,MAP4K4,EMP3,NUSAP1,TMEM147,EAF2,DDX39A,MAK16,PLEKHF2,RHEB,XRCC5,SDHB,GNAS,SLCO4A1,HSPBP1,PCM1,FNTA,ETS2,PITX1,MAPK6,ITGB1,E2F1,ACAT1,COPS6,CHMP7,NUDT11,USP13 |
| 1.591e-08 | -17.96 | spindle pole | cellular component | GO:0000922 | 152 | 50 | 18223 | 2701 |
BCCIP,CTDP1,PKP4,KLHL21,RAE1,POC1A,CENPF,TPX2,CCNB1,SPDL1,MAPK14,RAB11A,TUBGCP2,SPAG5,CALM2,CEP104,SMC3,NEK6,ABRAXAS2,PRC1,KNTC1,CEP63,CDC25B,TACC3,DCTN1,PLK1,PSRC1,TCTEX1D2,ASPM,NEK7,CUL3,TUBGCP5,CKAP2L,CDC6,TOPORS,AURKB,KIF11,TMEM201,HAUS8,KIF2A,PPP2CA,DSN1,GOLGA2,FAM110A,ODF2,FAM83D,NUP62,VPS4A,NDE1,WDR62 |
| 1.597e-08 | -17.95 | MOOTHA_MITOCHONDRIA | MSigDB lists | MOOTHA_MITOCHONDRIA | 415 | 106 | 17377 | 2626 |
NDUFA5,COX15,IMMT,TOMM20,NDUFB6,SUCLG1,MRPS15,MRPL39,MDH2,RAF1,GLUD1,BCL2L1,OAT,SDHA,RPAIN,APP,MRPL19,SLC25A37,BCAT2,VAV1,FARSA,DECR1,GOT2,TIMM23,DUT,MRPL34,CS,HADHB,MRPS27,FAM3A,HTRA2,GPX4,BAK1,IDH3A,CPOX,CYP20A1,MRPL12,VDAC2,SLC25A22,NDUFA7,NDUFB1,POLG2,SLC25A5,MBD3,MRPS14,PDHX,MRPL2,DAP3,TIMM13,TONSL,TIMM17A,MLYCD,COX5A,UQCRH,CLN3,MRPL13,SLC30A9,COX5B,NDUFV2,NDUFS1,MRPL9,MRPL42,MUT,MRPS2,SLC25A12,NDUFA4,COX4I1,CYCS,NDUFS4,SLC25A36,NDUFA2,NDUFB4,CRAT,BDH1,BCL2,NDUFS8,MRPL48,POLR1B,CYC1,MRPL11,ACAD8,NDUFA3,PPA1,MTX2,LYPLA2,SLC25A1,DDX28,TIMM8B,ABCF2,TUFM,MRPS10,MRPL16,MTX1,TOMM40,CYB5A,MFN2,GNAS,CAT,SDHB,MTHFD2,PRDX3,COX8A,ACAT1,ACADM,IDH3B,MRPL3 |
| 1.602e-08 | -17.95 | MRPL58 (mitochondrial ribosomal protein L58) | protein interactions | 3396 | 242 | 74 | 17029 | 2761 |
KARS,IMMT,CYLD,MRPS15,MRPL39,GLUD1,OAT,SDHA,APP,MRPL19,FLAD1,MRPL50,GRSF1,MRPS27,MRPL32,CLPTM1,MRPL12,MRPL43,VDAC1,SLC25A5,MRPS14,RCC1L,STOML2,MRPL2,DAP3,MRPL55,CHCHD1,PRDX5,MRPL27,MRPL13,RPS15,NDUFS1,MRPL9,MUT,MTERF1,MRPL42,PHB2,MRPS2,TWNK,FLOT1,MRPS26,SLC25A12,COX4I1,SIKE1,ATP5F1B,NDUFV1,NDUFA2,MRPL54,NDUFS8,MRPL40,MRPL48,CYC1,MRPL11,ALDH18A1,NSUN4,MRM3,SLC25A1,NIPSNAP1,DDX28,COQ8A,NOA1,TUFM,RPL6,MRPS10,MRPL16,THNSL1,EIF4H,ECH1,SYNCRIP,LRPPRC,SRSF3,ATP5F1A,HNRNPDL,MRPL3 |
| 1.619e-08 | -17.94 | DOUGLAS_BMI1_TARGETS_UP | MSigDB lists | DOUGLAS_BMI1_TARGETS_UP | 528 | 128 | 17377 | 2626 |
SNX27,NDUFA5,ASH1L,TMEM184B,LUZP1,UGP2,SUCLG1,SLC2A1,UCK1,USP39,SLC29A1,POLR3K,CD320,OIP5,EIF4A3,RALB,IL6ST,ADCY9,AKAP8,ATP13A3,CS,RP2,CORO1A,TOP1MT,ATF2,TIPARP,F2R,DNMT1,MTPN,CARM1,NOL12,PPIF,ARHGAP17,TIMP2,ATG9A,IDH3A,E2F3,MTMR6,GLO1,DIDO1,ICMT,UBTF,PWWP2B,TRAM2,DAP3,TMEM41A,DUS3L,ACYP1,CHD3,ZNF367,SOCS4,FTSJ1,ATE1,NCLN,SCARB1,REEP4,LRP8,EYA2,ZNF146,NCOR2,KIAA0100,SLC41A1,B4GALT5,TCF3,ANKH,TRMT6,DLGAP4,DHX9,LAMTOR3,MED13L,KLF13,GTF3A,PAWR,AKT1S1,SPR,ITGB5,PITHD1,ARID1B,NEIL2,SPAG5,XPR1,ZNF92,UBE2Q2,CLIC4,INPP5A,HDAC7,PRC1,SS18L1,CLDND1,CITED2,C12orf75,LPCAT1,ALDH9A1,RBM15B,CARS2,VOPP1,ILF3,RTF1,RIT1,PCGF1,KIF11,MACF1,CCT8,RBM38,MAPK3,SH3BP5,SLCO4A1,OSBPL11,KPNA1,TMEM54,FAM110A,PRPS2,FAM83D,PIAS2,SLC16A1,AEN,IMPDH1,PITPNA,HMGB2,CNOT6,RBPJ,RUVBL2,PLOD3,NR2F2,YWHAH,HIPK3,HRAS,CABLES1 |
| 1.627e-08 | -17.93 | GNF2_FEN1 | MSigDB lists | GNF2_FEN1 | 55 | 26 | 17377 | 2626 |
GINS1,NASP,HNRNPAB,FOXM1,RAD51AP1,CENPF,RRM1,DNAJC9,RACGAP1,NUSAP1,MCM2,SHCBP1,GAR1,KIF11,FANCI,DTL,CCNA2,PCNA,KIF18B,MCM5,DUT,PRC1,MSH2,HMGB2,CCNB2,SMC4 |
| 1.631e-08 | -17.93 | REN_BOUND_BY_E2F | MSigDB lists | REN_BOUND_BY_E2F | 62 | 28 | 17377 | 2626 |
POLA2,TK1,RFC3,H2AFZ,PRIM2,PRKDC,PTTG1,DBF4,E2F3,RRM1,CDC6,SMC2,ORC1,RFC2,RB1,PCNA,CCNA2,BRD2,RBL1,MCM5,DUT,MSH2,H2AFX,NAP1L4,CDK2,E2F2,SMC4,CSTF1 |
| 1.679e-08 | -17.90 | OXFORD_RALA_OR_RALB_TARGETS_UP | MSigDB lists | OXFORD_RALA_OR_RALB_TARGETS_UP | 45 | 23 | 17377 | 2626 |
PPIF,NET1,E2F3,TMEM97,RRM2,DNAJC9,CDC6,AURKB,PLXNA1,MCM2,STMN1,SLC20A1,SAC3D1,DTL,FARSA,BIRC5,MCM5,PSMD3,H2AFX,CENPM,ERI3,UBE2C,TACC3 |
| 1.695e-08 | -17.89 | AGUIRRE_PANCREATIC_CANCER_COPY_NUMBER_UP | MSigDB lists | AGUIRRE_PANCREATIC_CANCER_COPY_NUMBER_UP | 268 | 76 | 17377 | 2626 |
KCTD7,EXOC3,WDYHV1,UBE2Z,IRF3,SIRT2,BECN1,SDHA,GNB2,KTN1,CYHR1,PDK2,UTP18,CD3EAP,INTS1,LRRC59,SMARCE1,ZC3H3,ORAI2,KAT7,MTMR6,ATP6V0A1,WDHD1,RPS9,PAF1,TAF2,EIF3K,PON2,PSMD8,MAFK,LUC7L3,RNF38,CRCP,SMURF1,MRPL13,BRD9,AP2S1,ZNF146,CMAS,STRN4,CBLL1,EPN1,EZH1,SLC35B1,SLC12A9,RSAD1,CNOT3,MLX,SS18L1,CYC1,LPCAT1,CNPY3,EEF1D,KDELR1,NUDC,PHF20L1,FAM49B,TSTA3,PARP4,ARPC1A,DERL1,NUCB1,TPD52L2,PDCD6,CDC27,DUSP3,NSF,ACLY,NUP62,RUVBL2,SNRNP70,PLOD3,TAF6,ACSF2,RNF139,CDKN2A |
| 1.698e-08 | -17.89 | signal transduction by p53 class mediator | biological process | GO:0072331 | 132 | 46 | 17256 | 2622 |
MIF,FOXM1,TMEM109,CDIP1,CCNB1,CNOT11,FOXO3,JMY,CNOT3,TFAP4,PDK2,MDM2,PCNA,SP100,CENPJ,MSH2,CDKN1B,GTSE1,TP53BP2,CNOT6L,CARM1,PLK3,PGAP2,BTG2,USP10,TOPORS,BRCA1,SOX4,CNOT9,HINT1,RPS27A,HIPK2,E2F4,TFDP1,E2F1,PML,AEN,STK11,DDX5,CNOT6,CHEK2,TFDP2,CDK2,E2F2,ZMAT3,IFI16 |
| 1.700e-08 | -17.89 | PSMB6 (proteasome subunit beta 6) | protein interactions | 5694 | 83 | 35 | 17029 | 2761 |
USP7,CYLD,ZCCHC8,DCTN2,CUL1,POMP,RAD23A,KIF5B,PSMD2,MDM2,PSMD1,PSMA6,UCHL5,FBXO7,CAPZA1,FBL,DCTN1,PLK1,PSMA8,PSMB7,PSMA1,KRAS,SYVN1,CAPZA2,MCM2,PSMB9,PSMB3,PSMC4,DERL1,PSMD3,PSMD8,ASNA1,CDK2,PSMC1,PDCD4 |
| 1.703e-08 | -17.89 | GO_RIBOSOME | MSigDB lists | GO_RIBOSOME | 212 | 64 | 17377 | 2626 |
RPS15,RPS2,MRPL9,MRPL42,RPLP2,MRPS2,MRPS15,MRPL39,MRPS26,RPL15,EIF2AK4,MRPL19,RPL11,RPL23A,MCTS1,MRPL50,RPL17,RRBP1,MRPS27,MRPL34,MRPL54,RPL19,RBM3,MRPL40,MRPL48,MRPL21,MRPL11,RPL22L1,NSUN4,MRPL32,RPL29,RPL35,NCK1,MRPL12,RPS10,MRPL43,RPL6,RPL8,RPL38,MRPS10,RPS24,MRPL16,NDUFA7,RPL27A,MRPS14,ABCF1,SERP1,RPS9,RPSA,RPL36,RPL37,MRPL2,DAP3,RPL32,MRPL55,RPS27A,RPS14,EIF2D,MRPL27,RPLP1,FAU,MRPL13,RPS26,MRPL3 |
| 1.722e-08 | -17.88 | RAB2A (RAB2A, member RAS oncogene family) | protein interactions | 5862 | 113 | 43 | 17029 | 2761 |
CHMP2A,FGFR1OP,PHB2,RAC1,TMEM109,LAMTOR3,FLOT1,RAB6A,CNTROB,ARF1,RGS2,ATP6V1B2,RAB11A,CDC73,BCAP31,RPA2,RPN1,DNAAF2,ZFYVE27,SUCLG2,BCAP29,RNF26,ATF2,ATP6V0D1,POC5,DCTN1,MAPKAPK3,RAB7A,ILF3,GORASP2,VDAC1,RAB1A,RAB5B,CBFB,RAB2B,RPA1,CHCHD3,ATP1A1,GOLGA2,MAPK6,CTSA,ACTB,ACADM |
| 1.751e-08 | -17.86 | Mitotic G1-G1/S phases | REACTOME pathways | R-HSA-453279 | 143 | 51 | 10287 | 1696 |
POLA2,MAX,MCM10,CDT1,DBF4,CUL1,ORC1,CCNB1,PSMD9,FBXO5,LIN9,RPA2,CDKN2C,RB1,PSMD2,PCNA,PSMD1,PSMA6,CCNA2,MCM5,CDKN1B,ORC3,PRIM2,AKT2,MYBL2,PSMB7,E2F3,PSMA1,RRM2,CDC6,MCM2,PSMB9,PSMB3,PSMC4,RPA1,PRIM1,PPP2CA,POLE,RPS27A,RBL1,PSMD8,PSMD3,E2F4,TFDP1,E2F1,TFDP2,RBBP4,CDK2,E2F2,PSMC1,CDKN2A |
| 1.761e-08 | -17.85 | RPS18 (ribosomal protein S18) | protein interactions | 6222 | 157 | 54 | 17029 | 2761 |
RPS15,RPS2,CYLD,RPLP2,EIF3D,LAMTOR3,RPL15,CUL1,CSNK2A1,CCNB1,APP,RPL11,RPL23A,KRR1,RPL17,HUWE1,MCM5,AHSA1,RPL19,TARDBP,EIF3L,RPL35,RPS10,MRPL43,RPL6,CUL3,RPL8,RPL38,MRPS10,ATP6V0A1,RPS24,BRCA1,MCM2,RPL27A,RPS9,RPSA,EIF3A,PHF6,RPL36,CAND1,MRPL2,ATP6V1D,RPS14,RPLP1,H2AFX,WDR76,RRS1,FAU,CDK2,SMURF1,CD81,RPS26,MRPL3,PARD3 |
| 1.761e-08 | -17.85 | RPL12 (ribosomal protein L12) | protein interactions | 6136 | 157 | 54 | 17029 | 2761 |
COX15,RPS2,CYLD,EWSR1,RPLP2,MECP2,RPL15,CUL1,SDHA,APP,RPL11,RPL23A,PA2G4,PTEN,RPL17,HUWE1,CTR9,RPL19,TARDBP,HNRNPM,CDC5L,RPL29,RPL35,VHL,MRPL12,RPS10,RPL6,CUL3,ILF3,RPL8,RPL38,TUFM,RPS24,BRCA1,VDAC1,MCM2,RPL27A,RPS9,DHX15,RPSA,CAND1,RPL36,AKAP1,NAP1L1,RPL32,RPS14,RPLP1,FUS,FAU,CDK2,ARRB2,CD81,RPS26,ZC3HAV1 |
| 1.765e-08 | -17.85 | GSE17721_PAM3CSK4_VS_GADIQUIMOD_1H_BMDC_DN | MSigDB lists | GSE17721_PAM3CSK4_VS_GADIQUIMOD_1H_BMDC_DN | 185 | 58 | 17377 | 2626 |
KIF3B,MRPL9,MCM10,ANXA6,CXXC1,HNRNPUL2,ASAH1,NIPA2,ABCB10,GYG1,XPO7,BLM,DUSP22,PSEN1,HAUS2,CPNE3,RNF103,USP5,SEC11A,MRPL50,DECR1,RAP1A,SMC3,CBWD2,UTP18,BDH1,HADHB,ATP6V0A2,GLTP,CORO1A,PACS2,LYPLA2,SMC4,ELOF1,SP3,KLF10,GALC,GABPA,WDR1,IDH3A,NQO2,ZNF574,JTB,GMFB,PSMA1,TOR1AIP2,TOPORS,EIF3A,SRSF1,NAP1L1,SERF2,NIP7,ARNTL,ACADM,CLN3,YWHAH,PTDSS1,ZNF146 |
| 1.765e-08 | -17.85 | GSE10239_NAIVE_VS_DAY4.5_EFF_CD8_TCELL_DN | MSigDB lists | GSE10239_NAIVE_VS_DAY4.5_EFF_CD8_TCELL_DN | 185 | 58 | 17377 | 2626 |
PTMS,GNPDA1,RRM1,CDCA8,ABCB10,LACTB2,ORC1,AP3S1,PMVK,STMN1,HLA-A,SSR1,DTL,RFWD3,IRF4,ERH,DECR1,CCNA2,ATP2A2,MCM5,DUT,RAD23B,RRBP1,PRC1,KIF22,MDFIC,KNTC1,SAP30,GINS1,PLK1,CYFIP1,TK1,NRAS,MLEC,RFC3,PBK,E2F3,CCDC34,WDHD1,AURKB,SMC2,DDX39A,PRIM1,STT3A,NEIL3,ZNF367,MAPK6,CDCA5,SIAH2,PGRMC1,HMGB2,KPNA2,NAA20,EHD4,CCNB2,LRP8,DYNC1LI2,FAF1 |
| 1.765e-08 | -17.85 | GSE25088_WT_VS_STAT6_KO_MACROPHAGE_DN | MSigDB lists | GSE25088_WT_VS_STAT6_KO_MACROPHAGE_DN | 185 | 58 | 17377 | 2626 |
TMEM106C,POLA2,PKP4,H2AFZ,TXN,FOXM1,RAC1,CENPF,UCK2,TPX2,KIF2C,CCNB1,NCAPG,FZD6,SPAG5,MAN1A1,DTL,OIP5,PCNA,PSMA6,SLC1A4,PPME1,KIF14,PRC1,H2AFY,MDFIC,MAST2,ERI3,MRPL11,DNMT1,MSH6,GINS1,SLC39A9,ELOVL5,RFC3,RHOBTB3,ASPM,PRKDC,RAD51AP1,KIF15,MKI67,RRM2,NUSAP1,PKMYT1,ASB13,KIF11,MAT2A,ASF1B,RHEB,CHAF1A,CDCA4,MEGF9,SLC16A1,KPNA2,PIEZO1,SMAD1,CCNB2,SMARCD1 |
| 1.783e-08 | -17.84 | positive regulation of nucleobase-containing compound metabolic process | biological process | GO:0045935 | 1736 | 345 | 17256 | 2622 |
ZNF496,H2AFZ,CXXC1,HEXB,YTHDF3,CCNL2,CCNB1,EDRF1,PARK7,GLMP,CALM2,USF1,NOL11,DNM2,TRA2B,ECD,DNMT1,SENP1,CDC5L,BAK1,ERCC1,KLF10,AATF,GABPA,MRNIP,TOPORS,USP22,AURKB,CBFB,RFC2,ARF4,STOML2,DOT1L,MAP3K4,HHEX,SMAD2,RPS27A,AXIN1,OGT,RNASEL,TFDP2,SMAD1,ARRB2,E2F2,SLF1,NMD3,HDAC2,DDX58,HIVEP3,HSPH1,CHTF18,PRKAA1,DHX9,EZH1,PSMD9,PARN,PSEN1,METTL3,CDC73,DDRGK1,TFAP4,MSH2,FOXN2,MYDGF,PABPC1,NUP85,FOXK1,MTA2,MYBL2,BCLAF1,EXOSC9,ARID1A,SRSF5,ADRB2,ELK1,KDM3A,MAP2K2,CCT8,XRCC5,SERTAD2,ETS2,SETD3,RBMX,PIAS2,PPP3R1,CEBPG,YY1,MAP3K5,RNF14,CDK2,ZC3HAV1,EGLN1,RHOG,KARS,TRERF1,IVNS1ABP,RPS6KA1,RAF1,MAGED1,RAC1,CREBL2,APP,CCNA2,SHC1,SP100,GMEB1,LPIN2,MAVS,ATF2,RBM15,RPRD1B,CDK12,CCT2,PSRC1,BRD4,RFC3,KAT7,WBP2,E2F3,PFKFB3,EDF1,MEF2D,TAZ,TRIM28,SUPT16H,DDX17,TAF2,VEZF1,SAFB,HIPK2,H2AFX,STAT1,ATF6,BEND3,EYA2,ATMIN,POU3F2,MECP2,TCF3,BABAM1,HABP4,ABHD14B,WDR5,BLM,ETS1,FOXO3,MAD2L2,WWP2,GTF2F1,CCNK,PRDM4,CARF,CITED2,CNOT6L,CREB1,NCOA2,MSH6,PPP3CA,KAT2A,NEK7,RFXANK,ILF3,ZP3,KLF6,PICALM,FADD,POLR2A,GPS2,PITX1,TFDP1,PML,KHSRP,DDX5,HMGB2,CD81,USF2,YWHAH,RORB,CCNC,ZBED3,ZNF76,IER2,HNRNPAB,AGRN,THOC1,AAMDC,NF1,KMT2E,GPBP1L1,SIRT2,MAPK14,CREM,TET3,PCNA,GLIS2,METTL14,ZNF639,ETV6,PIK3R2,TCEA1,MYBL1,ARID4A,CARM1,ELOF1,RYBP,SP3,DEAF1,EXOSC6,NCK1,VHL,MRPL12,UBE2V1,LRP5,BRCA1,EAF2,SOX4,USP21,UBTF,PAF1,E2F4,ZNF268,CHEK2,DVL1,POT1,PSMC1,ZNF564,PPP1R12A,CHCHD2,CTCF,MEF2A,CDK13,PPP3CB,THRAP3,RLF,ASXL2,CRLF3,ARID1B,SUB1,RB1,MLX,NFATC3,TIGAR,MED10,SSBP3,ZNF746,CTR9,TIMELESS,ICE2,YBX1,MDFIC,MAML1,ERLIN1,LDB1,UTP15,RTF1,EIF2A,NFATC2IP,IRF5,CAND1,RXRB,PSMC4,TBPL1,NLRC5,NUP62,ZFP90,RUVBL2,SNRNP70,TOB1,SMARCD1,USP7,TCF12,ASH1L,FOXM1,SMARCA4,PLAGL2,IRF3,PCBP1,HNRNPA2B1,RRN3,NRF1,BABAM2,NVL,PIN1,TARDBP,F2R,SPIDR,DVL2,PRPF19,MOSPD1,POU2AF1,TIMP2,POLR2G,BTG2,NFATC2,SRSF1,RBL1,HNRNPR,SCAP,STAT6,ARNTL,NCOA1,AKNA,MAPK1,SMAD4,NAT14,SLC30A9,BCL2L12,DNAJC2,EYA1,CDT1,AGO2,DBF4,KLF13,NKRF,HMGN3,PAGR1,TFRC,IRF4,NABP2,BRD7,ARHGEF2,SS18L1,PTGES3,STAT3,TGFB1,DCAF6,HMGN1,HMGN5,PRKDC,PRMT2,MEN1,MAPK3,TFEB,UPF1,ATAD2,TFE3,E2F1,KMT2B,PKD2,RBPJ,NR2F2,ZMIZ1,HRAS,SLF2,IFI16 |
| 1.791e-08 | -17.84 | KPNB1 (karyopherin subunit beta 1) | protein interactions | 3837 | 247 | 75 | 17029 | 2761 |
ZNF207,NDC1,NUP188,UQCR10,RAC1,PMS2,TPX2,UBE2I,SDHA,PAPOLA,KIFC1,PRKD3,SNUPN,NUP210,NUP107,HADHB,NUP153,RPRD1B,SENP1,SEH1L,CDC5L,CUL3,NUSAP1,NUP155,CDCA2,NFATC2,BRCA1,NUTF2,MCM2,VDAC1,PPP2CA,SMAD2,CHD3,CLK3,CEP55,KPNA2,FUS,ARRB2,SMURF1,SMAD4,AAAS,SMNDC1,UNK,RAE1,CDT1,NUP54,CSNK1A1,NUP205,PTPN2,CCNK,SMC3,HUWE1,AHSA1,GLE1,NUP85,TERF2,HP1BP3,YTHDC1,STAU1,MTA2,DCAF8,RANGAP1,ADRB2,CDK11A,CAND1,DERL1,KPNA4,KPNA1,NSF,NUP62,RUVBL2,SMPD4,CDK2,TERF1,IPO4 |
| 1.835e-08 | -17.81 | chromosome, centromeric region | cellular component | GO:0000775 | 193 | 59 | 18223 | 2701 |
ZNF207,SKA3,DNMT3A,HJURP,PPP1R12A,DYNLL1,CDT1,CENPF,DCTN2,CDCA8,CTCF,NUF2,KIF2C,PMF1,CCNB1,SPDL1,CSNK1A1,NCAPG,PSEN1,MEAF6,SPAG5,MIS12,OIP5,AHCTF1,SMC3,KMT5C,SUV39H2,NUP107,PDS5B,H2AFY,KIF22,SS18L1,CENPM,KNTC1,DNMT1,NUP85,SEH1L,DCTN1,PLK1,FAM172A,WDHD1,RANGAP1,AURKB,SEPT7,PHF6,CENPU,CBX3,PPP2CA,KIF18A,DSN1,FBXO28,PPP2R5A,BIRC5,ZNF330,CDCA5,BAZ1B,CENPT,NDE1,DYNC1LI2 |
| 1.856e-08 | -17.80 | GO_UBIQUITIN_LIKE_PROTEIN_TRANSFERASE_ACTIVITY | MSigDB lists | GO_UBIQUITIN_LIKE_PROTEIN_TRANSFERASE_ACTIVITY | 406 | 104 | 17377 | 2626 |
MIB2,CCNC,UBE2E2,TRAF7,UBR2,TRIM11,XIAP,KLHL18,CUL1,UBE2Z,UBE2Q1,UBE2I,ANKIB1,BIRC2,RNF103,FBXO22,ZER1,FANCL,MDM2,FBXL6,CDC42,SIAH1,ATG3,FBXW2,TTC3,MARCH2,RNF19A,RLIM,PRPF19,BIRC3,RBX1,VHL,RNF25,CUL3,TOPORS,UBE2V1,KIAA1586,BRCA1,CDC23,TRIM28,RAD18,NSMCE2,RNF38,UHRF2,TRIM32,FBXL3,SMURF1,TRAF5,CBX4,UBE2D3,TRIP12,KLHL21,SHPRH,ZFP91,UFC1,BRAP,CBLL1,ZNRF3,UBE4A,WWP2,FBXO3,DTL,HERC3,RFWD3,RNF121,UBE2Q2,MED10,KLHL5,KLHL20,HUWE1,ZNRF2,HDAC7,PPIL2,FBXO7,LTN1,FEM1B,FBXL7,UBE3B,UBE3C,RNF135,LRSAM1,UBE2M,RNF5,UBE2QL1,TNFAIP3,RFFL,FBXO9,ANAPC2,UBE4B,SYVN1,FBXO21,KEAP1,BIRC5,KLHL15,KBTBD7,SIAH2,DTX4,PIAS2,RNF14,UBE2C,RNF139,ANAPC4,CDKN2A,RNF114 |
| 1.870e-08 | -17.79 | MORF_EIF4A2 | MSigDB lists | MORF_EIF4A2 | 133 | 46 | 17377 | 2626 |
RPLP2,EIF3D,SUMO2,NACA,TOP2B,UBE2I,CRLF3,MYL6B,CCDC28A,RPL11,TERF2IP,DNAJC8,RPL17,H2AFY,YBX1,RPL19,NAP1L4,PCBP2,SRSF11,RHOA,SNRNP200,RNPS1,RPL6,RPS24,SEPT7,EIF4G2,DDX39A,EIF3H,RXRB,DDX17,NSA2,DAP3,NAP1L1,PPP2R5A,BRD2,RPS27A,HNRNPH3,COX7A2L,UQCRH,YWHAZ,DDX5,BTF3,FAU,IDH3B,SNRNP70,TERF1 |
| 1.877e-08 | -17.79 | endomembrane system organization | biological process | GO:0010256 | 399 | 103 | 17256 | 2622 |
TMED7,CHMP2A,NDC1,NUP188,PDCD6IP,TOR1AIP1,ANK3,VTI1A,AGFG1,CCNB1,SEC16A,STAM,ANKLE1,UBXN2A,NUP210,ATP2A2,NEK6,CDC42,NUP107,NSFL1C,ZFYVE27,NUP153,TARDBP,LMAN1,RNF26,F2R,SEH1L,DCTN1,PLK1,ANKLE2,PLK3,CLCN3,USO1,AKT2,NUP155,TOR1AIP2,RAB1A,CHMP2B,STX16,RAB5B,RAB22A,SERP1,OPTN,PPP2CA,TRAM2,CHMP4A,SEC61A1,SURF4,TMED10,UBXN2B,GOLGA8A,MYO18A,CHMP4B,CLU,VPS4A,REEP4,RTN3,ABCA1,AAAS,CSNK1D,TMEM33,GOLPH3L,GORASP1,RAE1,SRGN,FLOT1,NUP54,TMED3,CSNK1A1,RAB11A,VPS25,WRB,NPLOC4,NUP205,LMNA,PDCD10,PTEN,VMP1,BANF1,ARL6IP1,CREB1,NUP85,TMED2,GCC2,COG1,GORASP2,PI4K2A,LEMD2,SEC31A,TMEM127,RAB18,SEC23IP,HGS,GOLGA2,STX18,TBPL1,VCPIP1,NUP62,YWHAZ,CCNB2,CHMP7,NUP58,ALS2 |
| 1.890e-08 | -17.78 | DNA Repair | REACTOME pathways | R-HSA-73894 | 316 | 91 | 10287 | 1696 |
USP7,KDM4A,XAB2,SUMO2,CHD1L,PMS2,ALKBH5,RMI2,INO80E,UBE2I,FANCI,MBD4,RAD23A,FANCL,PCNA,BABAM2,CCNA2,XRCC2,RAD23B,TCEA1,AQR,OGG1,SPIDR,PRPF19,COPS8,TDP1,ERCC1,RFC3,POLR2G,POLR2L,RBX1,RAD51AP1,PPIE,POLR2D,BRCA1,DCLRE1C,RFC2,FANCE,RAD51C,RAD18,RPS27A,FAAP100,H2AFX,BAZ1B,KPNA2,XRCC3,ACTB,CHEK2,COPS6,PPP5C,GEN1,XRCC4,EYA2,RAD51D,POLQ,CLSPN,POLR2K,EYA1,BABAM1,BLM,RMI1,MAD2L2,NPLOC4,NEIL2,DTL,RPA2,XPA,MSH2,TIMELESS,COPS7B,GTF2H2,MSH6,HMGN1,POLR2I,POLK,PRKDC,TOP3A,USP10,MPG,POLR2A,ISG15,RPA1,XRCC5,PALB2,POLE,POLR2J,PARG,YY1,ZNF830,CDK2,DDB1 |
| 1.908e-08 | -17.77 | GSE17974_1H_VS_72H_UNTREATED_IN_VITRO_CD4_TCELL_UP | MSigDB lists | GSE17974_1H_VS_72H_UNTREATED_IN_VITRO_CD4_TCELL_UP | 172 | 55 | 17377 | 2626 |
BCCIP,RMND5A,CTU2,ZBTB10,MAX,GPR132,FAM53C,CAST,TRMT6,NUP54,DHX8,MYNN,SECISBP2,IP6K2,RAPGEF6,SCYL2,JMY,DNAJB9,ANKRD28,MOAP1,PRKD3,SYNM,TIMM23,AKAP8,ZNF326,JOSD1,RHBDD2,ATP6V1G1,FYTTD1,IFRD1,PHF20L1,NXT1,NET1,ZNF202,GTPBP4,UTP15,CUL3,DDX20,GORAB,TMEM201,MAT2A,MTMR3,VEZF1,SYNCRIP,CCDC86,DUS3L,ZHX1,SPATA2,FAM3C,ZNF268,DUSP11,FBXL3,SMAD1,SLC25A33,ADNP2 |
| 1.908e-08 | -17.77 | GSE21063_3H_VS_16H_ANTI_IGM_STIM_BCELL_DN | MSigDB lists | GSE21063_3H_VS_16H_ANTI_IGM_STIM_BCELL_DN | 172 | 55 | 17377 | 2626 |
TCF12,PIGN,PKP4,TRERF1,NDUFAF2,MCCC1,TMX3,FLOT1,TIA1,ABCB10,SLC4A2,PPP3CB,RMI1,COMMD8,RHBDD1,FANCI,DECR1,RALB,TBC1D22A,CENPJ,BANF1,PHF14,NUP107,PIGG,TIMELESS,AFF1,MAVS,RNASEH2A,MYBL1,CARS2,UBQLN4,TCTEX1D2,ZNF512,ZMYND11,RAB3IP,AZI2,GSTCD,RHOT1,MEN1,PDE3B,ERC1,EPRS,TSC1,TMED10,CSK,CCDC14,WDR59,USP32,ATE1,TAF6,FAM208A,PDSS2,CHID1,ALS2,TMEM131 |
| 1.926e-08 | -17.77 | Srp72 (signal recognition particle 72) | protein interactions | 66661 | 208 | 66 | 17029 | 2761 |
BCCIP,DDX47,NOP2,URB2,YTHDC2,SND1,MEAF6,RPL11,RPL23A,HNRNPA2B1,FBXL6,NVL,POP7,FTSJ3,MLST8,RFC3,RBX1,NSUN2,RIOX2,DNAJC9,AURKB,DIDO1,PBRM1,RFC2,RPS9,DHX57,SUPT16H,CHD3,RPS14,TBL3,H2AFX,BAZ1B,FAU,RPS15,CMAS,RPS2,RPL15,NKRF,BLM,HMG20A,PNO1,LYAR,RPL17,PHF14,RPL19,DDX31,NSUN4,MRM3,HP1BP3,STAU1,DDX24,TEX10,RPL8,GTPBP4,RPL6,RPS10,RPS24,USP10,MPG,CCDC71L,RPL27A,RPL36,NAP1L1,RPL32,CCDC86,BYSL |
| 1.942e-08 | -17.76 | COPS6 (COP9 signalosome subunit 6) | protein interactions | 10980 | 306 | 88 | 17029 | 2761 |
KCTD7,USP7,TXN,HNRNPAB,RPLP2,SLC2A1,KLHL18,CUL1,SDHA,RBM4,FBXO22,RPL11,HNRNPA2B1,CDKN2C,CCNA2,SYNM,DDA1,POP7,CDKN1B,TFG,COPS8,ORAI2,RBX1,RPL38,CUL3,HNRNPF,TOR1AIP2,PRKRA,SLC25A5,BTBD1,RAD54B,PRIM1,RPS14,RPLP1,COX5A,ACTB,FUS,SNRPG,KLHL42,COPS6,FAU,MAPK1,PDCD2L,TUBB,CWC25,MIF,RPS2,EWSR1,CASP6,RAE1,CENPF,RPL15,PMF1,LRRC14,RPA2,DTL,ERH,SMC3,KLHL20,CCP110,PTEN,FBXO7,FEM1B,COPS7B,RPL22L1,PABPC1,UBE2M,TK1,MAPKAPK3,DCAF8,RPL8,RPL6,MAP7D1,PRDX1,HSPA1B,FBXO21,SYNCRIP,HNRNPH3,KLHL15,MAPK6,DCAF11,DDX5,PSAP,WIPI2,SNRNP70,CDK2,HNRNPDL,DDB1 |
| 1.948e-08 | -17.75 | RHODES_UNDIFFERENTIATED_CANCER | MSigDB lists | RHODES_UNDIFFERENTIATED_CANCER | 66 | 29 | 17377 | 2626 |
GCLM,H2AFZ,SEC61B,DPM1,FOXM1,POLR2K,PSMB7,TAP1,MYBL2,KIF23,CDC6,KIF2C,CCNB1,MCM2,PSMD2,PCNA,MTHFD2,CCNA2,EIF2S2,BIRC5,KIF14,H2AFX,CEBPG,SLC16A1,YBX1,HMGB2,KPNA2,UBE2C,TUBB |
| 1.957e-08 | -17.75 | GSE22886_NAIVE_CD8_TCELL_VS_NEUTROPHIL_UP | MSigDB lists | GSE22886_NAIVE_CD8_TCELL_VS_NEUTROPHIL_UP | 181 | 57 | 17377 | 2626 |
C9orf78,SCAMP3,SUCLG1,SRSF6,GLUD1,HMGN3,PPP3CB,SUPT7L,PPP1R16B,HDDC2,MOAP1,RPA2,ATP2A2,ZNHIT6,BANF1,FBXW2,TNPO2,SUCLG2,UBE3C,TERF2,ACSL5,MAPRE2,TSPYL4,CYP20A1,TUFM,PSMA1,EZR,ITM2A,UTP3,TMEM147,CDC23,PRKRA,MACF1,APPL1,MTR,TARS,SNRPA,CLNS1A,RPA1,YIF1A,MAP3K4,ANKRD10,EPRS,FBXO21,WDR11,EIF2D,FAM3C,LRPPRC,MPV17,PIEZO1,B4GALT3,CD81,CCDC59,PFKP,SSRP1,ADNP2,PRPF4B |
| 1.957e-08 | -17.75 | GSE43863_TH1_VS_LY6C_INT_CXCR5POS_EFFECTOR_CD4_TCELL_UP | MSigDB lists | GSE43863_TH1_VS_LY6C_INT_CXCR5POS_EFFECTOR_CD4_TCELL_UP | 181 | 57 | 17377 | 2626 |
WSB2,GALK1,DNAJC2,MCM10,LUZP1,CLSPN,GNPDA1,PDAP1,UFC1,TKT,KIF23,NUF2,GTF3A,INO80E,STMN1,FBXO5,DTL,SNRNP25,ERH,SLC31A1,PSMD1,UCHL5,EI24,SEPT11,TACC3,PDLIM2,GINS1,BAK1,HEMK1,ASPM,RAD51AP1,TUFM,DNAJC9,CKAP2L,CDCA2,UBE2V1,BRCA1,NUTF2,VDAC1,ANLN,RFC2,EIF4H,GLOD4,KIF2A,NUCB1,NAP1L1,POLE,HINT1,ORMDL2,CDCA7L,NRM,GPI,SCARB1,IDH3B,AP2S1,AAAS,PFKP |
| 1.960e-08 | -17.75 | GNF2_RPA1 | MSigDB lists | GNF2_RPA1 | 27 | 17 | 17377 | 2626 |
ZCCHC8,HNRNPF,SNRPD3,DHX15,SRSF1,RPA1,XRCC5,HSPB11,RBMX,U2SURP,NUP153,ANP32E,SRSF3,PTGES3,HNRNPM,SRSF10,SSRP1 |
| 1.971e-08 | -17.74 | SANSOM_APC_TARGETS_REQUIRE_MYC | MSigDB lists | SANSOM_APC_TARGETS_REQUIRE_MYC | 190 | 59 | 17377 | 2626 |
SRM,ZBED3,TP53RK,GNPNAT1,SHPRH,FLYWCH2,PMF1,SLC35B2,POFUT1,MYEF2,WRB,PABPC4,FZD6,WDR48,RAD23A,DTL,GTPBP3,NRF1,HOMER1,SIVA1,EXOSC1,AXIN2,TIMELESS,GTSE1,RNASEH2A,AQR,FBL,OGG1,ZNF800,MED22,PPAN,METTL1,TELO2,ERCC1,TK1,KAT2A,RNASEH2C,SIGMAR1,LDB1,RPS10,ARHGEF12,SOX4,MBD3,GAR1,POLE,CCDC86,DUS3L,HAGHL,CTBS,WDR4,USP20,GALNT10,SNRPG,ZSWIM3,WDR62,LRP8,AAAS,ATMIN,PTOV1 |
| 1.971e-08 | -17.74 | GSE43260_BTLA_POS_VS_NEG_INTRATUMORAL_CD8_TCELL_DN | MSigDB lists | GSE43260_BTLA_POS_VS_NEG_INTRATUMORAL_CD8_TCELL_DN | 190 | 59 | 17377 | 2626 |
KIF3B,NDUFV2,RECQL,RPS2,PHB2,HLA-E,MANBA,UBXN1,PRKAA1,ARID5A,MYH9,SLC4A2,PPP3CB,CDIPT,ZNF518A,LYN,EXT2,PTPN2,HERC3,RPL17,ZNF200,CS,AHCY,UBE3C,SLC35A1,PABPC1,EEF1D,ALDH9A1,TNFAIP3,DHX29,AMD1,FRAT2,GLO1,TXNL4A,CLNS1A,ANKRD46,NSA2,NAP1L1,POLR2J,JAK1,NSF,CCDC6,DHX16,LSM6,ZNF330,UBXN2B,LRPPRC,WDR7,RPLP1,TBPL1,PKD2,ATF6,MRFAP1L1,MAP3K5,IGBP1,PTDSS1,N4BP2L2,TUBB,DDX52 |
| 1.984e-08 | -17.74 | nucleotide-excision repair | biological process | GO:0006289 | 116 | 42 | 17256 | 2622 |
SLC30A9,USP7,ATXN3,POLR2K,XAB2,SUMO2,CHD1L,UBE2I,NEIL2,RAD23A,RPA2,PCNA,XPA,RAD23B,COPS7B,TCEA1,AQR,GTF2H2,OGG1,PRPF19,COPS8,ERCC1,HMGN1,POLR2I,RFC3,POLR2L,POLR2G,RBX1,POLK,PPIE,POLR2D,RFC2,POLR2A,RPA1,POLE,POLR2J,RPS27A,NEIL3,ZNF830,COPS6,RAD51D,DDB1 |
| 1.990e-08 | -17.73 | GOLDRATH_HOMEOSTATIC_PROLIFERATION | MSigDB lists | GOLDRATH_HOMEOSTATIC_PROLIFERATION | 159 | 52 | 17377 | 2626 |
GALK1,CMAS,MRPL9,GOLIM4,MUT,GNPNAT1,PDAP1,LAGE3,DHX9,C5orf30,TM9SF3,CYCS,AGFG1,UBQLN2,BZW2,APP,PARK7,NUDT19,ATP6V0B,PELO,AKAP8,RAD23B,H2AFY,PDCD2,BCL2,CYB5R1,PTGES3,CREB1,PPA1,IMPA2,VOPP1,CCT2,EID1,VDAC2,GMFB,WIPF1,PBRM1,AMZ2,RAB18,PDCD6,STT3A,ZHX1,CDCA7L,PRPS2,SEL1L,E2F1,CHEK2,ROCK1,IGBP1,PTDSS1,BYSL,FUBP1 |
| 1.990e-08 | -17.73 | GO_CHROMOSOME_CENTROMERIC_REGION | MSigDB lists | GO_CHROMOSOME_CENTROMERIC_REGION | 159 | 52 | 17377 | 2626 |
ZNF207,SKA3,DNMT3A,PPP1R12A,HJURP,KDM4A,DYNLL1,DCTN2,CENPF,CDCA8,CTCF,NUF2,KIF2C,PMF1,CCNB1,CSNK1A1,PSEN1,MIS12,SPAG5,OIP5,SMC3,AHCTF1,SUV39H2,NUP107,PDS5B,H2AFY,KIF22,SS18L1,KNTC1,CENPM,DNMT1,NUP85,SEH1L,DCTN1,PLK1,MKI67,RANGAP1,AURKB,WDR81,SEPT7,PHF6,CBX3,PPP2CA,KIF18A,PPP2R5A,DSN1,BIRC5,ZNF330,CDCA5,BAZ1B,CENPT,NDE1 |
| 2.024e-08 | -17.72 | CDK4 (cyclin dependent kinase 4) | protein interactions | 1019 | 170 | 57 | 17029 | 2761 |
FOXM1,HMGXB3,CDT1,UBXN1,CIB1,CUL1,CDK13,ATP5F1B,DAZAP2,PSMD9,LYN,APP,CDKN2C,RB1,PCNA,SMC3,PSMA6,CCNA2,PTEN,ZNF335,CDKN1B,FNIP2,BCL2,TARDBP,GEMIN4,ORC3,ARID4A,NCOA2,LUC7L2,CDC37,NOL12,TK1,MAPRE2,ASPM,VHL,PRKDC,CUL3,DNAJC9,SLBP,CDC6,BRCA1,PKM,MCM2,OGFR,GFER,UBTF,SMAD2,BIRC5,RBL1,QARS,E2F4,UHRF2,FKBP5,CHEK2,COPS6,ARRB2,CDKN2A |
| 2.056e-08 | -17.70 | regulation of chromosome segregation | biological process | GO:0051983 | 100 | 38 | 17256 | 2622 |
ZNF207,CDT1,CENPF,PTTG1,RMI2,SMC6,CSNK2A1,CTCF,RACGAP1,KIF2C,SIRT2,CCNB1,BECN1,MAD2L2,SPAG5,RB1,NEK6,CDC42,AXIN2,H2AFY,TACC3,PLK1,CUL3,MKI67,CDC6,AURKB,CDC23,RAD18,CDC27,NSMCE2,CDCA5,XRCC3,UBE2C,SLF1,GEN1,SLF2,ESPL1,ANAPC4 |
| 2.098e-08 | -17.68 | GSE3920_UNTREATED_VS_IFNG_TREATED_ENDOTHELIAL_CELL_DN | MSigDB lists | GSE3920_UNTREATED_VS_IFNG_TREATED_ENDOTHELIAL_CELL_DN | 168 | 54 | 17377 | 2626 |
SRM,TMED7,COPA,TSC2,MRPS2,PIGQ,CSNK2A1,SLC25A44,SUPT7L,NDUFS7,FBXO5,CYHR1,GART,PSMD1,CTSS,MTMR4,SEC24C,TBC1D14,PTPN11,TIMELESS,ZBTB22,MRPL11,GPD1L,FGFR1OP2,NAGPA,UBQLN4,MLEC,ERMP1,PBK,WDR18,JTB,UBE4B,PBRM1,MEN1,MCM2,EDEM2,MBD3,ZDHHC3,USP21,AKAP1,MTMR3,GNA12,TMEM41A,ITPRIPL1,SEC23IP,TMEM168,DGCR8,SNAP23,SETD3,SCARB1,TRIM32,SPCS3,HIPK3,DDB1 |
| 2.165e-08 | -17.65 | GSE23321_CD8_STEM_CELL_MEMORY_VS_NAIVE_CD8_TCELL_DN | MSigDB lists | GSE23321_CD8_STEM_CELL_MEMORY_VS_NAIVE_CD8_TCELL_DN | 177 | 56 | 17377 | 2626 |
MAX,CDS2,NF1,UQCR10,DNAJB2,MON1B,LETMD1,ASAH1,BTN3A1,TGOLN2,IRF3,INO80E,ASXL2,RCOR3,ELMOD2,FAM8A1,ABHD14A,HEATR5B,SAC3D1,TMEM179B,MOAP1,DECR1,GSDMB,SNX18,TBC1D22A,RABGAP1L,DUT,CISD2,OSTF1,CGGBP1,TACC3,ABCC5,ERMP1,RPRD1A,PPP1R21,MAN1B1,TAOK1,HEBP2,EDEM2,PRMT2,KIF11,PDE3B,NMT2,EPB41,PRIM1,ALKBH6,WAS,ATAD2,CSK,RBL1,TMEM219,HMGB2,CABIN1,RNASEL,DYNC1LI2,ATMIN |
| 2.165e-08 | -17.65 | GSE17322_CD103_POS_VS_CD11B_HIGH_LUNG_DC_DN | MSigDB lists | GSE17322_CD103_POS_VS_CD11B_HIGH_LUNG_DC_DN | 177 | 56 | 17377 | 2626 |
MIF,RPS15,LYRM4,C19orf53,DHPS,ZNF768,UQCR10,WDR13,MDH2,EIF3D,PRKAA1,SLC25A12,GTF3A,AKT1S1,MYO9B,CUTC,RSAD1,SLC31A1,NDUFV1,GART,ITGB8,COQ4,KLHL5,BRD7,PARL,UBE3C,TPCN1,RNF5,CARS2,LDHB,COPS8,PHF10,KAT2A,ERLIN1,NUDT4,MRPL12,TUFM,RPL38,TBRG4,KIF11,TARS,TMEM201,EIF3K,SDHB,RPL32,GOLGA7,QARS,EIF2D,WDR7,BTF3,RRS1,LTA4H,PARP10,C7orf26,FAF1,ZNF146 |
| 2.170e-08 | -17.65 | GO_SIGNAL_TRANSDUCTION_BY_P53_CLASS_MEDIATOR | MSigDB lists | GO_SIGNAL_TRANSDUCTION_BY_P53_CLASS_MEDIATOR | 121 | 43 | 17377 | 2626 |
MIF,FOXM1,TMEM109,CCNB1,FOXO3,CNOT3,TFAP4,PDK2,MDM2,PCNA,SP100,CENPJ,MSH2,GTSE1,CDKN1B,TP53BP2,CNOT6L,CARM1,PGAP2,PLK3,BTG2,USP10,TOPORS,BRCA1,SOX4,RBM38,HINT1,RPS27A,HIPK2,E2F4,TFDP1,PML,E2F1,AEN,CNOT6,DDX5,STK11,CHEK2,TFDP2,CDK2,E2F2,ZMAT3,IFI16 |
| 2.184e-08 | -17.64 | GSE360_CTRL_VS_M_TUBERCULOSIS_DC_UP | MSigDB lists | GSE360_CTRL_VS_M_TUBERCULOSIS_DC_UP | 195 | 60 | 17377 | 2626 |
IER2,H2AFZ,UBN1,SRSF6,NACA,DCTN2,TRIO,HEXB,TOP2B,GGA2,ITGB5,FOXO3,SDHA,GIT2,PIP4K2A,TBC1D22A,SIVA1,H2AFY,ANP32A,SLC38A10,AHCY,TARDBP,SMARCE1,KDELR1,ABCC5,LDHB,SPTAN1,CDC5L,SP3,CYFIP1,TIMP2,SEPT9,KAT2A,ERF,DCAF8,IDH3A,SUGP2,HEBP2,GORASP2,DDX39A,H2AFV,ZDHHC3,EIF3H,FADD,MFN2,MYO1F,MAN2A2,MKNK1,RPS27A,STAT6,WDR7,CEBPG,MEGF9,MDH1,BTF3,LTA4H,USF2,YWHAH,SSRP1,DDX42 |
| 2.192e-08 | -17.64 | GSE24210_CTRL_VS_IL35_TREATED_TCONV_CD4_TCELL_DN | MSigDB lists | GSE24210_CTRL_VS_IL35_TREATED_TCONV_CD4_TCELL_DN | 186 | 58 | 17377 | 2626 |
SRM,POLA2,CTU2,HIVEP3,GCLM,LZTR1,NQO1,PHF23,PHB2,ZNF768,MDH2,UQCR10,UROD,MRPS26,RRM1,LAGE3,BZW2,PABPC4,KRR1,ERH,SUB1,NDUFV1,PCNA,ATP2A2,CD3EAP,DUT,PIN1,RAD23B,YIF1B,YBX1,AHCY,LYPLA2,FDFT1,TXNL1,SEC61B,PRIM2,TSTA3,IDH3A,RAB7A,WDHD1,TMEM147,MBD3,EIF3G,PRDX1,CLNS1A,HINT1,CERS6,TBL3,CEP55,DBI,ASNA1,ATP6V0C,SPRYD4,GCSH,FAF1,GPATCH4,DDB1,PTOV1 |
| 2.192e-08 | -17.64 | GSE37532_TREG_VS_TCONV_CD4_TCELL_FROM_LN_UP | MSigDB lists | GSE37532_TREG_VS_TCONV_CD4_TCELL_FROM_LN_UP | 186 | 58 | 17377 | 2626 |
MIF,SEPHS2,SRM,DNAJC2,NOP2,MRPS2,GPR89A,CHD1L,RBM8A,TMEM109,USP39,EBNA1BP2,SLC35B2,PARN,C19orf48,ABHD14A,PAPOLA,IRF4,DDX56,GART,EXOSC7,DUS4L,COQ4,SAR1A,ATIC,MRPS27,PARL,POLR1B,ALDH18A1,AHCYL1,TOP1MT,FTSJ3,EEF1D,MED22,METTL1,SRP72,POLR2I,LAP3,IDH3A,TMEM216,PCGF6,PSMG1,ADSL,CDC6,TMEM147,GAR1,TSR2,SF3A2,ZDHHC3,CLNS1A,ALG3,SLC19A1,NFIL3,AEN,IMPDH1,DTD1,GPATCH4,GPR89B |
| 2.192e-08 | -17.64 | GSE17721_POLYIC_VS_GARDIQUIMOD_0.5H_BMDC_DN | MSigDB lists | GSE17721_POLYIC_VS_GARDIQUIMOD_0.5H_BMDC_DN | 186 | 58 | 17377 | 2626 |
SLC30A9,IER2,DDX47,PDCD6IP,ANXA6,GORASP1,SF3B1,ANKH,RAC1,TIA1,DHX8,SMC6,NIT2,COMMD5,STAM,DNAJB9,SRXN1,RAP1A,RNFT1,TIMELESS,PARL,ANAPC7,CHTOP,ABI1,POC5,PDLIM2,MOB4,PDPK1,VOPP1,LARS,ARHGAP17,HMGN5,SNX2,CIC,KAT7,PPP1R21,RNF25,RABIF,NFATC2IP,DCUN1D5,TOLLIP,PRDX1,MAPK3,MRPL2,CCDC6,DHX16,PSMD3,PPM1G,ITGB1,USP20,STK11,CHMP4B,ATF6,SPCS3,RUFY3,CD81,SNX14,NUDT3 |
| 2.192e-08 | -17.64 | GSE27859_DC_VS_CD11C_INT_F480_HI_MACROPHAGE_UP | MSigDB lists | GSE27859_DC_VS_CD11C_INT_F480_HI_MACROPHAGE_UP | 186 | 58 | 17377 | 2626 |
DNAJC2,GCLM,SARNP,EWSR1,MOGS,PNO1,PABPC4,FANCI,RRN3,AHCTF1,PDCD10,PTEN,MCM5,PTPN11,BTF3L4,AKR1B1,NDUFS8,PTGES3,TMEM14C,SAP30L,NUP85,FTSJ3,MYO5A,MORC3,SRSF10,RPAP3,EIF3L,MKLN1,KAT2A,HARS,DRAP1,CPOX,RNPS1,SLBP,USP10,KRAS,NFATC2IP,NUTF2,DNAJA1,C9orf40,DDX39A,TSR2,SF3A2,PRDX1,CLNS1A,CAND1,PSMC4,PPP2CA,HSPBP1,EIF4ENIF1,TFDP1,CDCA7L,PRPS2,U2SURP,PIAS2,PITPNA,SSNA1,SNRPG |
| 2.192e-08 | -17.64 | GSE16450_CTRL_VS_IFNA_12H_STIM_MATURE_NEURON_CELL_LINE_DN | MSigDB lists | GSE16450_CTRL_VS_IFNA_12H_STIM_MATURE_NEURON_CELL_LINE_DN | 186 | 58 | 17377 | 2626 |
DDX58,PRKAB1,CASP6,ZCCHC8,DYNLL1,FAM129A,CENPF,TAP1,CHIC2,LANCL1,MAPK14,RHBDD1,PNO1,TNS3,MED8,ATP2A2,THADA,UTP18,GRSF1,ATP13A3,PPP4R1,KIF22,TAF5L,OSTC,CAMK2G,ABCC1,SP3,CPNE1,DDX28,PTPN18,TRAFD1,PPT1,AKT2,PBK,BTG2,ERLIN1,OXR1,HTATIP2,NUSAP1,WDR81,USP22,GSTCD,TXNL4A,RBM38,ASF1B,SOCS7,XRCC5,MRPL2,OSBPL11,JAK1,SERF2,ZFP90,SASS6,CD81,MAPK1,BRD9,E2F2,DYNC1LI2 |
| 2.197e-08 | -17.63 | negative regulation of mitotic cell cycle phase transition | biological process | GO:1901991 | 226 | 67 | 17256 | 2622 |
ZNF207,GPR132,CUL1,CCNB1,FANCI,PSMA6,PCNA,PSMD1,MDM2,CDKN1B,CTDSP2,CARM1,PLK1,PLK3,RBX1,PSMA8,BTG2,TAOK1,PSMB7,MRNIP,BRCA1,AURKB,SOX4,PSMB9,RPS27A,RBL1,PSMD8,PSMD3,E2F4,CHEK2,VPS4A,TFDP2,PSMC1,CLSPN,CDK2AP2,CENPF,BLM,CNOT11,PSMD9,CDC73,MAD2L2,CNOT3,RPA2,RFWD3,RB1,PSMD2,PTEN,CENPJ,FBXO7,BRD7,GTSE1,FBXL7,BCL2,CNOT6L,PRKDC,PSMA1,PRMT2,PSMB3,PSMC4,CNOT9,TFDP1,PML,E2F1,PKD2,CNOT6,ZNF830,CDK2 |
| 2.202e-08 | -17.63 | central_nervous_system | COSMIC cancer mutations | central_nervous_system | 16807 | 2544 | 17385 | 2587 |
HECA,ZBTB10,ABCC10,HEXB,CCNL2,FBXO22,EEF2K,THAP4,RAD23B,ATP13A3,DNM2,ZNRD1,FTSJ3,USP34,CCDC57,ERCC1,NRAS,EHMT1,KIF15,HNRNPF,WDHD1,MIER2,DIDO1,MCM2,RAB22A,SMAD2,MID1IP1,RPS27A,MYO18A,OGT,MPV17,COX5A,SMAD1,ZNF75A,ANXA11,SLC25A33,SEC61G,GGA1,MUM1,CCZ1,TRIO,CUTA,RAB23,KCTD17,HAUS4,EIF2AK4,APH1B,PARN,CDC73,MYL6B,ATG4A,TMEM179B,PDXP,SMC3,GEMIN4,MVP,NUP85,PPP6R1,PABPC1,NSUN4,PPA1,IFRD1,AGGF1,FOXK1,RBM42,GTPBP4,MAP7D1,MRPL16,ELK1,EIF4H,RDH11,MAGED2,KPNA1,ETS2,TYW5,WIPI2,RUFY3,PDLIM5,ACSF2,RHOG,EXOC3,STARD7,VTI1A,C5orf30,INO80E,SLC35B2,RCOR3,LCLAT1,CPNE3,KIAA1147,RBM23,ZNF420,AHCTF1,TBC1D22A,TBC1D14,GMEB1,NSFL1C,SEPT11,ZNF226,GPD1L,ZC3H3,ARL5A,PDCL3,SNX8,ERMP1,EID1,IDH3A,POLR2D,HTATIP2,MEF2D,TMEM147,GSTCD,TANC1,MAT2A,VPS26B,NSMCE2,CORO1C,CAMKMT,PPP5C,PITRM1,TUBB,COMMD10,ZNF445,SRSF6,HABP4,CCM2,FLOT1,BTN3A1,ATG2B,ABHD14B,PPP1R3B,GOLM1,ZBTB45,HUWE1,ZNF260,NAA50,ANXA5,LTN1,UBE3B,NAP1L4,ZNF710,ST8SIA2,RPL22L1,MED22,SPTAN1,STAU1,DDX24,TCTEX1D2,TACC1,MRS2,LDHA,HEBP2,LLPH,RAB3IP,TTC33,PICALM,SH3BP5,SLC19A1,ACOX1,FAM3C,AEN,PARP10,YWHAH,THAP5,GPATCH4,FAM129A,TRIM11,YTHDC2,SNX15,RBM8A,ENSA,NENF,SND1,RUFY1,TRIM65,ZER1,PRNP,KRR1,RAB8A,NUP210,NT5DC1,NOC2L,EIF5,TACC3,RYBP,VPS13B,PTPN18,MIOS,SNRPB,MBLAC2,CDC6,UTP3,PBRM1,ODC1,USP21,TRAM2,FBXO28,BCL7C,ARRDC1,ADAM9,DVL1,NUMB,ZNF564,FUBP1,C1orf74,CTU2,PARP12,ZCCHC9,CENPF,LAMTOR3,CHCHD2,NCKAP1,LYRM2,RSAD1,TNS3,SUB1,RINL,SSBP3,KIF13B,MBD2,XPA,AHCY,RBM3,GLE1,MRPL48,LRSAM1,HDHD2,NTPCR,NSDHL,AMD1,CAMSAP1,ZNF761,METTL22,ICAM2,STYXL1,APPL1,BBS12,ANKRD46,RXRB,SDHB,PCM1,GALNT2,TMEM168,NLRC5,RUVBL2,BTBD10,MYO9A,CCNB2,USP7,GLT8D1,RPLP2,SUCLG1,ARID2,TMX4,SLC2A1,ATP6V1B2,PCBP1,LYN,BCAP31,VAV1,TMEM69,MRPL50,PSMA6,ZNF473,ZNF302,BRPF3,TARDBP,BCAP29,CTDSP2,PRPF19,PPIF,KDM3B,MND1,CLCN3,BIRC3,RAB7A,ANKRD33B,PPIE,CHMP2B,VDAC1,EIF3H,TMEM201,GLOD4,IDE,DHX16,UHRF2,CHMP4B,XRCC3,PARD3,BCL2L12,C19orf53,MCM10,KLHL21,PDAP1,CDCA8,TMX3,ARF1,SLC12A9,TUBGCP2,DNAJB9,HOMER1,POLR1B,RNF5,RBM15B,PPAN,RHOA,RPRD1A,BTAF1,TOP3A,ARHGEF12,PCGF1,DDX23,RAB18,CACNB1,TRIM26,PDCD6,ATP6V1D,L3MBTL3,FAM110A,NEIL3,CTBS,BBX,IMPDH1,TAF12,NR2F2,PGAM1,HIPK3,IFI16,TXN,NUP188,H2AFZ,PNISR,TMEM203,PRKCSH,USP39,UBE2I,PARK7,SLC25A37,ASPHD2,ZNF428,RAB4A,TRA2B,SUCLG2,TAF5L,CISD2,SMARCE1,ZNF800,CDC5L,ZNF524,SGCE,OSBP2,NSUN2,USP22,CLNS1A,EIF3A,ZMYM3,DOT1L,IWS1,ANKRD10,WAS,KIF18B,TPP2,C1orf109,ZMAT3,B4GALT2,PRPF38B,RECQL,C9orf78,EWSR1,GADD45G,RRM1,ACAP1,B4GALT1,CYCS,FAM136A,SUPT7L,TMEM165,CNOT3,NPLOC4,WDR48,SPAG5,RTKN,CEP104,EXOSC7,KLHL5,LRRC8D,PPP4R1,MSH2,PIGG,OSTF1,FBXL7,MRPL40,TNRC18,SYTL3,FAM171A1,APOL1,EIF5A,GCC2,PRIM2,ELL2,RDH10,MFNG,RPS24,GORASP2,CAPZA2,ADRB2,CCT8,MTR,PHF6,PFDN5,SLCO4A1,TTC13,GOLGA2,RBMX,MED15,PIAS2,APPL2,SAMD8,CDKN2A,NUDT3,ZNF511,ATXN3,RAF1,KIAA0232,C2orf49,EPM2A,CD320,CCNA2,MTMR4,BRI3,TP53BP2,AQR,RBM12B,ILKAP,CDK12,SAP30,BRD4,DRAP1,NARF,LRRC8A,ELP4,ABHD11,PKMYT1,ASB13,SERP1,TRIM28,SUPT16H,EIF3K,CHMP4A,CBWD1,ATF6,XRCC4,PRPF4B,ADAM23,NDUFS1,DEPDC1,MECP2,SECISBP2,HMG20A,WWP2,JAKMIP1,SLC25A36,CCNK,DNAJC8,AXIN2,CITED2,JMJD4,ANKRD37,KAT2A,TMEM126B,RABIF,ADSL,PACS1,BMS1,KCNQ1,ARSK,MACF1,KIF11,COMMD4,KLF6,SMAP2,FADD,SH3GLB1,MYO1F,CBX3,TMEM127,INF2,PPP1R11,DUSP11,DDX5,WDR62,TAF6,ESPL1,PURA,DDB1,DEF6,FAM83G,IPO4,UBL3,PIGM,NAT9,LYRM4,GPR132,UBE2Q1,PTP4A3,BRIX1,MRPL19,ZNF696,SF3B2,PCYOX1L,CDC42,SYNM,GOT2,JAZF1,HADHB,RPF2,SLC35C2,CNNM3,CARM1,SRPK2,WDR41,LARS,ZCCHC10,CCDC138,LRBA,TMEM216,SUMF2,KMT2C,OGFR,PRPSAP1,ASF1B,RPL37,MAN2A2,EIF4ENIF1,NIP7,U2SURP,MIA2,ZNF268,VPS4A,ATP6V0E1,PPP1R2,PM20D2,XPNPEP3,RGS2,LYAR,FAM89B,POLR2I,TRAFD1,SUGP2,GBA,SYVN1,DAPK3,ARHGAP15,MASTL,UAP1,NFIL3,FN3KRP,YWHAZ,CTSA,TMEM14A,TOB1,TSEN15,ADNP2,TCF12,PRKAB1,MDH2,SMARCA4,ORC1,RRN3,UBXN2A,IARS,CD3EAP,KIF14,EXOSC1,CS,CLTB,DNAL4,CSTF1,POU2AF1,UBQLN4,NXT1,HPDL,PGGT1B,SELPLG,SMU1,ATXN1,GLO1,OGDH,BICD2,CADM1,EDEM2,HERPUD2,TOLLIP,FANCE,MBD3,PDHX,RPS9,ALKBH6,SURF4,DUS3L,ARNTL,ANP32E,FKBP5,TMEM101,CCDC125,ABCA1,PDCD2L,GCLM,RAE1,DCTN2,NUP54,CHIC2,PAWR,MXD4,DCUN1D4,PIP4K2A,XPR1,FERMT3,KIF5B,KLHL20,SEC24C,RRBP1,ARHGEF2,ANP32A,LDLRAD3,C12orf75,STAT3,MYO5A,NIPAL3,AMPD2,TXNL1,PHF20L1,DCAF6,FAM49B,TMEM39A,ATP2C1,RFFL,COG1,RCOR1,PRMT2,TFEB,LEMD2,UPF1,ELMO1,ZC3H7B,DTX4,ZMIZ1,TERF1,HRAS,CCDC93,FGFR1OP,TMED7,PIGQ,AGPAT1,CNTROB,PPP1R16B,MIS12,GSDMB,TTC9C,PDS5B,NUP153,SENP1,PGAP2,TMEM115,PLEKHM3,DCUN1D5,PLEKHF2,BRMS1,PWWP2B,TRIM47,WDR11,AXIN1,SMG9,TRIM52,LONP2,NDUFV2,PHF23,CERK,SLC4A2,EZH1,ITGB5,LMNA,MCTS1,FBRS,DDX56,EIF2S2,SLC38A5,FOXN2,CARS2,PRRC2A,C16orf72,RB1CC1,ZMYND11,PGS1,MYBL2,UHRF1BP1,SRSF5,MPG,MATR3,CYB5A,NCDN,POLR2J,SETD3,TEX30,PTAR1,CNOT6,NDE1,EGLN1,ZNF207,ANKRD27,PPP1R37,ABCA3,SARNP,IVNS1ABP,MON1B,RMI2,TMEM97,NIT2,NUF2,ZNF267,TCF19,TMEM161B,KTN1,APP,PRKD3,CLUAP1,ATP2A2,UTP18,GRSF1,DUT,ZCCHC2,ANAPC7,RNF19A,FAM76B,CLN6,TMEM9,GCC1,RNF169,ADCY7,ATP6V1G1,ENPP4,RNPS1,CDCA2,FKBP3,GPR137,DDX17,CHCHD3,PEX5,CDC16,HIPK2,MBOAT1,TICAM1,PDXK,ZBTB11,ANXA6,TMBIM4,GMCL1,UBE4A,IL21R,ETS1,WRB,ZNF92,PNO1,CAPN2,ADD3,SUV39H2,TTLL12,TPCN1,TMX1,HNRNPM,LYPLA2,MFSD12,LDHB,PPP3CA,NUDT8,POLK,JTB,EMP3,MTMR12,ZP3,PDE3B,KIF18A,CCDC6,WNT5B,MAPK6,C4orf46,LY75,SLC25A19,RGL1,PSAP,WDR76,IGBP1,FAF1,SNAPIN,COX15,THOC1,AGRN,GNPDA1,GPBP1L1,PPP1R15B,CSNK2A1,EBNA1BP2,GIT2,BIRC2,ATPAF1,DLG5,ABL2,XRCC2,ZFYVE27,MCMBP,PTPRK,CDC37,METTL1,SP3,EXOSC6,HARS,GMFB,ESYT1,ANLN,RAB5B,RHEB,DPYSL3,TBC1D17,TIMM13,CDCA4,TONSL,NRM,NAGLU,ACTB,ZNF45,TMUB1,CTCF,ASAH1,DOCK11,CRLF3,ASXL2,LRRC14,NUS1,SLC27A4,AFF1,MDFIC,MAML1,CYTH1,NQO2,UTP15,EIF2AK1,EIF4G2,ZDHHC3,MOSPD3,ITPRIPL1,CDC27,SNAP23,TBPL1,PRMT7,KCTD7,NDUFA5,CYLD,UGP2,DYNLL1,COPE,HCFC1R1,ZADH2,GGPS1,RPAIN,RAD23A,SEC11A,ATP6V0B,PDK2,STRBP,TNFAIP8,DUS4L,MRPL34,PDCD2,SAP30L,CLPTM1,SLC39A9,RPL29,RPL35,BTG2,DNAJC9,FRAT2,MTMR6,NFATC2,KDM1B,ARL5B,USP36,CCDC127,MRPL2,ATP1A1,CLK3,MAFK,PSMD3,NDUFA11,CEP55,ZNF436,DNAJC17,NCOA1,SLC25A39,ZC3HC1,ZNF146,ATXN7L2,CDC40,SMAP1,GOLIM4,RRP15,DAP,GNE,SMC6,ARFIP2,NKRF,CHAC2,BZW2,WRNIP1,SS18L1,CENPM,PTGES3,CAMK2G,MLEC,ZNF202,PPWD1,FAM50B,RHOT2,NEU1,TPD52L2,GOLGA7,TWSG1,GLG1,PGRMC1,FAM126A,SPCS3,RPS6KC1,UBE2C,PPCS,NDUFB6,TMEM41B,ZDHHC8,PLXNA1,CCNB1,SLC20A1,COMMD6,ABHD14A,POLR3K,C14orf119,ASAP2,SNUPN,CNPY4,TFG,PLCL2,SEH1L,ATG9A,PBK,MKI67,DDX20,AMDHD2,GALNT7,SLC17A5,CCNF,FOXRED1,RBM47,PTER,WDR4,DHTKD1,TRAF5,HDAC2,PWWP2A,HSPH1,LIME1,MAPRE1,CHTF18,ADO,KIF23,SLC35B1,NOTCH2,PMF1,JMY,NDUFAF6,FKBP1A,SLC31A1,SNX18,ATIC,ATP6V0A2,PIKFYVE,RNF135,LPCAT1,EEF1D,TMED2,PHF10,FTL,DDX28,ZNF84,SIGMAR1,PIP4K2C,RIT1,PLEC,KDM3A,SF3A2,FAS,EPRS,ZNF777,TMEM54,QARS,PPP3R1,TCOF1,NRBP1,CABLES1,DNMT3A,RWDD1,CKLF,TRIP10,SF3B1,RPS6KA1,SUZ12,CAST,RAC1,GPR89A,OLA1,SNN,GNB2,FLAD1,APLP2,KDM2A,TNPO2,CDKN1B,TALDO1,GPX4,ATP13A1,MAPRE2,RFC3,ERF,CUL3,SLBP,KIAA1586,H2AFV,POLG2,GAR1,PSMB9,DHX57,NSA2,HSPA4,MRPL55,JAK1,TBL3,SEL1L,H2AFX,KLHDC4,B4GALT3,PDCD11,ATMIN,POLQ,POU3F2,OTUD5,NCOR2,ANKRD13D,PKP4,SCAMP3,BABAM1,CDCA3,SLC25A12,BLM,TMCC3,GTF2F1,RPL17,CRAT,AHSA1,PRC1,UPF2,COPS7B,SLC38A10,CNOT6L,CNPY3,UBE2M,IFT46,TMEM160,TSHZ1,ZFP64,DENND4C,DENND1B,WDR18,RPL8,ILF3,LRRC1,RHOT1,MARK2,TSR2,ECH1,PRDX1,PLD3,NUCB1,FBXO21,GNA12,C1orf131,PRDX3,PFDN4,HNRNPH3,STX18,TFDP1,KHSRP,ASNA1,CPEB2,SSSCA1,BYSL,VPS29,S100PBP,MIB2,IER2,PTMS,NOP2,UBN1,DCAF15,NF1,FLYWCH2,ALKBH5,MOGS,UBE2Z,TAF6L,BECN1,MAPK14,SNAPC4,RNF103,BCAT2,MBD4,C18orf32,METTL14,IMPAD1,ZNHIT6,RCSD1,PHTF1,SRI,KIF22,ZBTB22,NFU1,OGG1,TRIM14,ELOF1,COPS8,FYTTD1,TRIM8,RRM2,SOX4,ABHD5,UBTF,CXXC4,PAF1,UEVLD,SPATA2,PQBP1,IARS2,ATXN2L,GALNT10,STARD3NL,RPS15,PIGN,AGTRAP,CIB1,XPO7,SRRT,ZNF449,CAPZA1,GLTP,BCL2,KIFAP3,N4BP2,HP1BP3,VOPP1,THNSL1,ISG15,CAND1,GNAS,TSC1,RBM25,CDCA5,ZFP90,NANP,RBBP4,ZBTB24,SMARCD1,MBD1,WASF2,MMACHC,TOMM20,IFI27L1,GNPNAT1,MPHOSPH8,HNRNPUL2,CHD1,MEAF6,C2orf68,CCDC50,AKAP8,PARL,RPN2,CHTOP,FAM3A,F2R,SCYL3,TMEM14C,ABI1,HTRA2,MOSPD1,RLIM,FAM172A,ZNF500,PSMB7,NLN,WIPF1,BOLA1,BUD13,NDUFB1,PEF1,EIF3G,BTBD1,TAB2,CHCHD1,TULP3,WDR59,CANT1,SCARB1,GAS2,USP11,SMURF1,PPP2R2D,TSPAN5,CDS2,MAGEH1,MRPL42,EYA1,CDK2AP2,MRPS26,LETMD1,KLF13,HDDC2,RGS1,MAN1A1,FBXO5,GART,PELO,TANK,BRD7,MRPL11,SAMD4B,ZDHHC18,GTF3C6,POLR3GL,WDR81,MEN1,ZNF407,MFN2,COX8A,ZRANB2,SRSF3,MBD6,ATP6V1C1,IDH3B,TATDN1,TSC2,LACTB2,CMTM6,RBM4,ZNF275,ANKRD39,RPL23A,CDKN2C,NAPG,USF1,MECR,AP1M1,UPRT,CRY2,ECD,RNF26,TIPARP,LRRC59,ANKRD9,MGAT5,RHBDD2,BAK1,ZNF559,RHOBTB3,GABPA,NUTF2,WBP1,GINS4,ARF4,KRIT1,BOLA3,AHNAK,RAD18,PDRG1,RNASEL,CHPF2,OAZ1,PDCD4,SMNDC1,NXT2,HIVEP3,KIAA0100,CLSPN,RHOC,DHX9,PDCD7,PSMD9,HAUS2,COPB2,TFAP4,CD59,RNFT1,RIMS3,MEGF8,EFTUD2,FBXO7,MRPL21,CPSF4,PHKG2,LUC7L2,SRSF11,EIF3L,MTA2,TYW1,USP10,ITM2A,SSR2,BCLAF1,MTX1,SFXN5,FNTA,PDLIM1,TXNDC16,TMEM159,ZNF830,MRPL3,ALS2,FAM72A,TRIM41,KARS,NQO1,POC1A,PTTG1,ANK3,TPX2,TBC1D13,DAZAP2,STMN1,GLRX3,C19orf48,REPS1,ABHD16A,FBXL6,SH3BP1,MTA1,UBA5,CLCN6,INTS12,C8orf59,RPRD1B,CGGBP1,CPNE1,SEC61B,POLR2L,FAM118B,GOPC,CRNKL1,E2F3,CIRBP,RPL38,PFKFB3,GORAB,RAB1A,GIGYF1,TMEM184C,PPP2CA,KIF2A,CCDC14,LSM6,RNF38,DMWD,SNRPG,USP13,MZT1,ZFP91,TRMT6,IP6K2,WDR5,SLC25A43,PMVK,IFT27,RRP36,NEIL2,SRXN1,RPA2,PSMD2,CLIC4,PDCD10,ITGB8,CBWD2,COQ4,ARF5,ARHGEF1,FBXL19,GTF2H2,TTPAL,UTP20,MAGT1,GPS2,DBI,MRFAP1L1,SSNA1,CD81,TMEM131,WDR13,FANCI,PAPOLA,CREM,FANCL,TET3,GLIS2,IL6ST,INTS1,POP7,SLC44A1,MTPN,ASB6,PLK1,RPP25,SEPT9,CELSR2,RBX1,APH1A,RAD51AP1,CKAP2L,PSMG1,UBE2V1,IL12RB1,EAF2,KRTCAP2,LUC7L,LSG1,NECAP2,C1orf122,ALG3,TRIM4,AGPAT2,CHD3,ZNF367,E2F4,PRPF4,KPNA2,BEND6,CLN3,DNAJC30,FAM208A,NGLY1,POT1,MYL12B,CCDC137,RMND5A,HJURP,PHB2,FAM53C,DNAJB2,NKD2,SDC2,KLC1,CDK13,ADCK5,COX4I1,RAB6A,DNAJB1,ARID1B,C1GALT1,MLX,UBE2Q2,CCP110,ZNF746,ARL6IP1,CTR9,NIPSNAP1,ABHD2,DCAF8,ACSL3,LDB1,MAP4K3,ARMC8,RBM38,IRF5,NMT2,RPL36,HAUS8,MBIP,ORMDL2,COX7A2L,ZDHHC7,FAM122A,SIL1,DTD1,UNC13C,BCCIP,SART1,TRAF7,NDUFAF2,TOR1AIP1,ZNF416,LAGE3,TM9SF3,ZFYVE21,RRAGC,ZNF121,OIP5,NRF1,WDR44,PIN1,PPME1,EFCAB11,RPAP1,CABLES2,TOP1MT,LMAN1,AHCYL1,STRAP,SPSB3,ZNF583,SNX25,ARHGAP17,POLR2G,ZNF780B,PPT1,NUP155,DCLRE1C,MRPS14,RHBDF2,SUGP1,RBL1,FASTK,UBXN2B,STK38,AP1S1,SPRYD4,SLC22A23,H3F3A,CHID1,SMAD4,RAD51D,SLC30A9,NADSYN1,UNK,CMAS,HMGN3,NCAPG,SCYL2,FZD6,HERC3,GTPBP3,CTSS,ORC3,RNLS,YTHDC1,ACP2,CSRP1,HMGN5,METTL5,ABCF2,TUFM,RANGAP1,PNPLA8,HAGH,API5,ZFR,SEC23IP,E2F1,USP20,TMEM219,RBPJ,MAX,PDCD6IP,LUZP1,GXYLT1,ADAM10,CXXC1,TSC22D3,AP3M2,CUL1,GYG1,NANS,OAT,MYEF2,ANKRD26,PA2G4,NOL11,FIZ1,ZNF200,MARCH2,SLC26A2,SRP72,KLF10,LACTB,RFC2,CBFB,RAB2B,PRIM1,MAP3K4,HHEX,RPS14,LUC7L3,MAP4,MRPL27,BTF3,PTPDC1,CCDC59,NMD3,PTOV1,COX5B,DNAJC5,SCOC,DHPS,POLR2K,ANKH,PRKAA1,VAV2,C16orf87,GSPT2,DLGAP4,TATDN3,PXMP2,PRPF39,PSEN1,ZNF79,PDXDC1,VPS25,NDUFS7,YY1AP1,C12orf10,FAM192A,RPN1,LHX8,ARPC5,ZNRF2,DAPK1,TPST1,PIK3IP1,CYC1,SOCS5,FDFT1,PIGT,WDR1,EMB,ZNF574,C1orf35,EXOSC9,ARID1A,PTTG1IP,C9orf40,FXR1,GOSR1,MAP2K2,TWISTNB,AKAP1,XRCC5,HMGN2,PI4K2A,CAT,SEC31A,DERL1,HSPBP1,MTHFD2,CEBPG,ARAP1,FAM83D,USP32,CABIN1,SMPD4,GPI,CYTIP,TP53RK,REPS2,RAB11B,UROD,SLC39A13,POMP,BCL2L1,NUDT19,DECR1,RALB,SIAH1,LPIN2,ADCY9,SOCS6,MRPS27,TTC3,RNASEH2A,CFL1,ANKLE2,CDC123,OAF,VDAC2,EDF1,ERC1,EML4,AMZ2,ANKZF1,ZNF282,RAD51C,DSN1,DDOST,HINT1,DGCR8,SAFB,HAGHL,LMBR1,RWDD4,FTSJ1,NCLN,BEND3,EYA2,DYNC1LI2,B4GALT5,SLC41A1,MANBA,TKT,FAM76A,CBLL1,ARGLU1,LANCL1,POFUT1,FAM8A1,HEATR5B,HLA-A,EBP,RFWD3,NDUFA2,FUT8,BTF3L4,PTPN11,MRPL54,FEM1B,RPL19,CNN2,NDUFA3,MTX2,MSH6,PDLIM2,LONRF3,RFXANK,FBXO9,GUF1,RPL32,ZHX1,NDUFS5,WDR91,GPR89B,HIGD2A,ZBED3,RORB,POLA2,ZNF76,MTX3,COPA,UQCR10,HMGXB3,PHRF1,ABCB10,COMMD5,MAP1LC3B,DST,SIVA1,RAB35,GPATCH1,TCEA1,DRAM2,DEAF1,SNRNP200,NCK1,LAP3,VHL,SREK1,ARHGDIB,PITPNB,HSPB11,BRWD1,PPM1G,SH3GLB2,CRCP,BAZ1B,CAB39,ACBD4,STK11,CLU,CHEK2,ZSWIM3,TSTD2,MRPL13,CHPT1,DCAF5,CAPN1,UBE2D3,NSMCE4A,PPP1R12A,ZCCHC8,GORASP1,NACA,UBXN1,PCSK7,RPL15,THRAP3,TTF1,QSOX2,PRPF18,NUP205,CHKA,DTL,MED10,ZRANB1,MCPH1,SLC12A2,ATP6V0D1,CSNK1G3,CREG1,NUDT4,RPL6,VKORC1,SLTM,EVC2,KLHL15,SIAH2,SLC16A1,EHD4,SNRNP70,C11orf1,APOL2,N4BP2L2,SNX27,CHMP2A,CORO7,FEZ2,UCK2,PMS2,UCK1,CLCC1,EXT2,MXD1,USP5,HNRNPA2B1,SAP130,NVL,PPP6C,CYB5R1,ZNF770,EBAG9,RNF25,PCGF6,METTL2A,FAM72B,PON2,HNRNPR,STAT6,HPS5,MAPK1,BRD9,TMEM33,NAT14,DNAJC2,TRIP12,SHPRH,SCYL1,VPS45,MYO9B,GFM2,SPPL2A,FASTKD3,FGFR3,MZT2A,PPIG,ZDHHC13,TMEM99,H2AFY,ATG13,NDUFS8,ERI3,FBL,SLC35A1,FRMD8,MICAL3,TGFB1,B3GALT6,ELOVL5,HEMK1,TIMMDC1,HELB,PSPC1,MIER1,SCFD2,NDRG3,ARL17A,CDK11A,MTMR3,MEGF9,ACAT1,CENPT,PLOD3,RAB3IL1,ZSWIM6,RAB14,ADD1,MRPS15,KDM4A,XIAP,DHX8,GLUD1,ANKRD23,PABPC4,CALM2,CDK5,PSMD1,NEK6,NSRP1,RABGAP1L,SRSF4,FNIP2,KCNAB2,PCBP2,MLST8,PLK3,ZNF672,MRPL43,HSDL1,TOPORS,MCL1,SMC2,PPFIA3,ICMT,SLC50A1,STOML2,LIMK1,ZNF689,PRDX5,ATE1,MLYCD,ATP6V0C,ST3GAL2,FBXL3,TFDP2,E2F2,PFKP,AAAS,DDX42,SSRP1,MRPL9,MRPS2,STRN4,TOP2B,ZNRF3,TMED3,DDRGK1,RAVER2,GNS,INTS7,INPP5A,MCM5,PHF14,ZNF326,UBE2QL1,NAGPA,TIMM8B,ETV3,TSPAN31,DHX29,TEX10,MAN1B1,RPS10,CBFA2T2,ABCF1,RHOB,LRRC14B,DTWD1,PTPRF,SCARB2,OSBPL11,CCDC86,DUSP3,SLAIN1,MDH1,HEXA,RNF139,SNX14,ZNF296,TRERF1,UBR2,CHD1L,ACTR3,WDTC1,MYH9,CREBL2,NIPA2,PRKACA,SAFB2,ANKIB1,STAM,ARL6IP6,RAB21,SP100,ZKSCAN1,DDA1,NUP107,ANKRD13C,MAVS,CEP63,TMEM136,RBM15,ATF2,DCTN1,SHOC2,PSRC1,MAP4K4,WBP2,ATP6V0A1,NUSAP1,NDUFA7,DNAJA1,TAZ,C19orf54,TAF2,SEC61A1,WDR7,RPLP1,CBLN2,RBMS1,FUS,GEN1,LRP8,COIL,LRCH1,GALK1,ZNF786,RPS2,SESTD1,TRAK1,JMJD6,SIKE1,AKT1S1,KRI1,FBXO3,ERH,GATC,NDUFB4,PPP1R8,PRDM4,GTSE1,GEMIN6,DCP1A,SGCB,S100A6,IMPA2,NUDC,PDPK1,TK1,GUK1,TNFAIP3,GALC,ZNF512,KIAA0930,MRPS10,DDX39A,RPA1,ZNF180,ZNF862,KEAP1,POLE,TATDN2,PITX1,CAPN7,LRPPRC,PML,HMGB2,USF2,ANAPC4,SRM,DDX47,MCCC1,CDC42SE2,S1PR2,CDIPT,SEC16A,KCMF1,SSR1,LIN9,PCNA,ZNF639,TRMU,PIK3R2,ETV6,PPCDC,TXLNA,FAM86C1,MYBL1,MRPL32,CCAR1,ABCC5,PBXIP1,BAZ2A,TLK1,MRPL12,EZR,LNX2,LRP5,BRCA1,PRKRA,STX16,EPB41,OPTN,SEPT1,SOCS4,QRSL1,PIEZO1,OSGEPL1,GLCCI1,NUDT11,GEMIN7,SEPHS2,LZTR1,RACGAP1,PPP3CB,B4GALT4,RLF,RAPGEF6,SNRNP25,RB1,VASP,MED8,VMP1,PPIL2,MEA1,TIMELESS,AHDC1,ALDH18A1,TMEM8A,ABCC1,PREB,TRAPPC9,AACS,MEMO1,KRAS,RTF1,UBE4B,NFATC2IP,LY6E,ARPC1A,ZNF174,PSMC4,GOLGA4,SYNCRIP,PALB2,PRPS2,NIPA1,TIGD2,RNF114,FOXM1,MRPL39,XAB2,SUMO2,DUSP22,COMMD8,RPL11,CSDE1,MDM2,CORO1A,METTL9,MINPP1,POC5,DVL2,GM2A,PSMA8,COQ10B,CPOX,TIGD5,SLC26A6,CYP20A1,PRPF3,TXNL4A,RPSA,SRSF1,DNAJC10,SCAP,ZNF700,PLEKHG4B,TIMM17A,FAU,LTA4H,AP2S1,USP53,INTS2,CTDP1,MIF4GD,CDT1,ARID5A,SUMF1,GGA2,AP3S1,CSNK1A1,RMI1,TFRC,PTPN2,STARD9,IRF4,GSTK1,NDUFV1,SLC1A4,CWC27,SLC35B4,DDX31,ABCD1,RPAP3,CNTN5,SNX2,ZMYM5,CCDC34,CHCHD6,BSDC1,KPNA4,CDKN2AIPNL,FBXO41,BIRC5,TFE3,SNAP29,CDCA7L,PKD2,ACADM,CHMP7,SAT2,GCSH,ZNF496,TMEM109,TAP1,NHLRC3,IKBIP,EIF1B,ELMOD2,KIFC1,DBNDD1,CYB5RL,PARPBP,RNASEK,CDC25B,PRADC1,DNMT1,NOL12,ORAI2,USO1,AKT2,NOL8,GNG7,AURKB,MCFD2,SLC25A5,ZFAND5,MAK16,STT3A,TMED10,PSMD8,EIF2D,ITGB1,PTPN7,UQCRH,RRS1,ARRB2,RTN3,ZNF598,SVIP,DDX58,WSB2,PPIB,MUT,GMFG,HLA-E,NDUFA4,MAN2B1,METTL3,CFLAR,NDUFS4,RNF121,MEX3C,KLF16,HDAC7,DAD1,BDH1,PCYT2,GNAI2,ANKHD1,TERF2,MORC3,KCTD20,SEPT8,DCTD,PKM,TOMM40,PATL1,ADSS,SERTAD2,SERF2,ZFP92,NSF,DCK,ERGIC3,ACLY,LPCAT4,VCPIP1,YY1,PPP6R2,PPP6R3,MAP3K5,RNF14,CDK2,ZC3HAV1,SYS1,ZBTB37,URB2,EIF3D,MAGED1,KLHL18,ADPGK,SLC25A44,AP1B1,SDHA,PAIP2,PHC2,CRKL,TERF2IP,MOAP1,CYHR1,ZNF75D,SHC1,UCHL5,NAA35,TMBIM1,CCT2,CDKN2AIP,MKLN1,HMGN4,LYRM1,GALK2,CDC23,SHCBP1,AP4E1,PRDM11,VEZF1,PPP2R5A,ACYP1,STAT1,PPA2,TRIM32,RHEBL1,C1orf112,TCF3,MRI1,BRAP,AGPAT3,MYNN,SDF2L1,SPR,RAB11A,REEP5,FOXO3,MAD2L2,CCDC28A,PIP5K1C,RBM17,MAT2B,PTEN,CENPJ,TAGLN2,OSTC,CREB1,PACS2,NCOA2,SMC4,RNASEH2C,NEK7,NET1,PARP4,TBRG4,ANAPC2,RPL27A,YIF1A,SGSH,HGS,TTLL4,SLC38A7,MFAP1,CCDC69,BRWD3,ESYT2,SKA3,NPHP4,UBE2E2,HNRNPAB,PLXNC1,TMEM184B,ST13,DNAJC24,ZNF107,KIF2C,SLC29A1,AGFG1,SIRT2,FKBP2,USP48,SNRPD3,UBQLN2,CUTC,EDC3,UBLCP1,ZNF804A,RAP1A,THADA,EIF4A3,AP3S2,ATG3,DPYSL2,PPP1R12C,AKR1B1,NDUFB9,JOSD1,RP2,TTC4,TECR,ARID4A,FGFR1OP2,TIMM50,TDP1,DPM1,FOPNL,SLC16A7,WDR82,SLC25A22,STK17B,DHX15,CHAF1A,GEMIN5,COPS6,SASS6,RPS26,PSMC1,SLC12A7,TBC1D12,TM9SF4,ZNF768,UFC1,MED13L,TIA1,MEF2A,EPHX2,PITHD1,RHBDD1,NFATC3,BANF1,ZNF335,BUD31,YBX1,KNTC1,ACAD8,UBE3C,ZNF189,ALDH9A1,KDELR1,TSTA3,CIC,OXR1,PSMA1,TMEM241,SEPT7,NAP1L1,ODF2,EXOC4,KIAA1328,NUP62,PITPNA,NAA20,PTDSS1,MZT2B,PDSS2,C7orf26,TMEM106C,IMMT,ASH1L,CHERP,WDYHV1,PLAGL2,CHKB,IRF3,TWF2,PAIP1,ANKRD28,ANKLE1,FARSA,SAR1A,SCAMP4,APOOL,PDIA6,ACSL5,TOR1AIP2,AZI2,GFER,RAD54B,TMEM41A,DAP3,ZNF317,GADD45B,AKNA,REEP4,CBX4,MIF,KIF3B,GOLPH3L,SH2D3A,CASP6,TOR3A,SRGN,DBF4,MFSD10,SAC3D1,CTNNBL1,YIF1B,CLDND1,TTC17,SLC25A1,GINS1,PAQR6,CSNK1G2,TELO2,ADAM17,HMGN1,NASP,ASPM,PPP1R21,PRKAR1B,SYMPK,TARS,SNRPA,MAPK3,HSPA1B,HLA-B,ATAD2,PLAA,ZNF330,OSBPL8,KBTBD7,PREPL |
| 2.212e-08 | -17.63 | ATPase activity | molecular function | GO:0016887 | 456 | 115 | 17224 | 2647 |
DDX47,ABCA3,DYNLL1,ABCC10,CHD1L,YTHDC2,TAP1,PMS2,OLA1,MYH9,DHX8,SMARCA4,ABCB10,KIF2C,ATP6V1B2,ATP5PF,CHD1,KIFC1,ATP6V0B,ATP2A2,EIF4A3,KIF14,XRCC2,ATP13A3,KIF22,TAP2,DNAL4,ABCC5,ATP6V1G1,SNRNP200,RHOBTB3,ATP13A1,RFC3,KIF15,ATP6V0A1,DDX20,PBRM1,RFC2,DHX15,DHX57,RAD54B,DDX17,KIF2A,RAD51C,HSPA4,ATP1A1,IDE,RAD18,KIF18B,CHD3,DHX16,MYO18A,ATP6V0C,XRCC3,CLU,VPS4A,PSMC1,LONP2,ATP6V0E1,ABCA1,RAD51D,DDX42,POLQ,KIF3B,RECQL,HSPH1,CHTF18,TOR3A,DHX9,KIF23,TOP2B,MYO9B,ATP5F1B,BLM,WRNIP1,KIF5B,DDX56,KIF13B,MSH2,ATP6V0A2,ABCD1,DDX31,GTF2H2,ATP6V0D1,MSH6,ABCC1,DDX28,DDX24,DHX29,HELB,ABCF2,ATP2C1,ATP5MF,DDX39A,MACF1,KIF11,ABCF1,CCT8,HSPA1B,PSMC4,XRCC5,DDX23,ATP6V1D,UPF1,KIF18A,ATAD2,ATP5MC3,NSF,DDX5,ASNA1,RUVBL2,ATP5F1A,RBBP4,ATP6V1C1,DDX52 |
| 2.230e-08 | -17.62 | GO_ENDOMEMBRANE_SYSTEM_ORGANIZATION | MSigDB lists | GO_ENDOMEMBRANE_SYSTEM_ORGANIZATION | 448 | 112 | 17377 | 2626 |
CHMP2A,PDCD6IP,NUP188,SYS1,TOR1AIP1,ANK3,RAC1,VTI1A,AGFG1,CCNB1,SEC16A,STAM,UBXN2A,RAB8A,NUP210,NEK6,ATP2A2,CDC42,NUP107,NSFL1C,ZFYVE27,NUP153,TARDBP,LMAN1,F2R,SEH1L,PLK3,ANKLE2,PLK1,CLCN3,AKT2,EZR,TOR1AIP2,NUP155,RAB1A,CHMP2B,STX16,RAB5B,RAB22A,SERP1,OPTN,PPP2CA,CHMP4A,SEC61A1,SURF4,TMED10,UBXN2B,TULP3,MYO18A,CHMP4B,CLU,ROCK1,VPS4A,REEP4,SMURF1,RTN3,TSPAN5,ABCA1,AAAS,CSNK1D,TMEM33,GOLPH3L,GORASP1,RAE1,SRGN,FLOT1,NUP54,NKD2,CSNK1A1,RAB11A,RAPGEF6,VPS25,WRB,NUP205,NPLOC4,LMNA,PDCD10,PTEN,VMP1,BANF1,PPIL2,ARL6IP1,CREB1,NUP85,PACS2,MYO5A,TMED2,GCC2,DENND4C,COG1,PACS1,MACF1,LEMD2,TMEM127,RAB18,HGS,GOLGA4,SEC23IP,GOLGA2,GOLGA7,NSF,OSBPL8,STX18,TBPL1,VCPIP1,NUP62,YWHAZ,FAM126A,ASNA1,CHMP7,CCNB2,ALS2 |
| 2.243e-08 | -17.61 | H3F3A (H3 histone family member 3A) | protein interactions | 3020 | 110 | 42 | 17029 | 2761 |
ASH1L,KDM4A,UBN1,SF3B1,SMARCA4,PAWR,THRAP3,SF3B2,SAP130,MCM5,H2AFY,FBL,MSH6,CARM1,NUDC,NASP,SNX2,POLK,ZMYND11,PRKDC,EHMT1,MCM2,KMT2C,KIF11,TRIM28,ASF1B,CHAF1A,CBX3,SUPT16H,XRCC5,KPNA4,CORO1C,CDCA5,PML,CABIN1,FUS,RBBP4,PARP10,CBX4,IPO4,VPS29,SSRP1 |
| 2.269e-08 | -17.60 | GO_NUCLEAR_OUTER_MEMBRANE_ENDOPLASMIC_RETICULUM_MEMBRANE_NETWORK | MSigDB lists | GO_NUCLEAR_OUTER_MEMBRANE_ENDOPLASMIC_RETICULUM_MEMBRANE_NETWORK | 936 | 203 | 17377 | 2626 |
RAB14,TMED7,PIGM,COPA,TMEM203,PIGQ,MOGS,TMEM109,TAP1,AGPAT1,FKBP2,IKBIP,CDIPT,BECN1,SEC16A,RNF103,SSR1,DST,NUP210,CDC42,CYB5RL,RAB35,TTC9C,SRI,ZFYVE27,NUP153,CISD2,MARCH2,TECR,SPTSSA,LRRC59,PGAP2,DPM1,ATG9A,APH1A,ESYT1,PITPNB,NUTF2,MCFD2,ICMT,KRTCAP2,RHEB,RAB2B,ALG3,AGPAT2,TMED10,STT3A,PIEZO1,CLN3,RTN3,SVIP,PIGN,AGTRAP,SEC61G,HLA-E,UBXN1,NOTCH2,SLC35B1,TMED3,RAB6A,PSEN1,COPG2,RHBDD1,COPB2,NPLOC4,DDRGK1,FKBP1A,CD59,RNF121,RPN1,NUS1,LRRC8D,DAD1,EI24,ARL6IP1,PIGG,SLC27A4,BCL2,PCYT2,LPCAT1,TMED2,KDELR1,PREB,FDFT1,EIF5A,PIGT,SIGMAR1,ERLIN1,NSDHL,MAN1B1,ACSL3,RDH10,SSR2,SYVN1,VKORC1,CYB5A,RDH11,MOSPD3,SEC31A,DERL1,GALNT2,ORMDL2,ERGIC3,LPCAT4,NUP62,SAMD8,SMPD4,MAP3K5,PTDSS1,RNF139,APOL2,TMEM106C,RHOG,ATXN3,CHERP,RAC1,COPE,VTI1A,SLC35B2,LCLAT1,BCAP31,EXT2,KTN1,SEC11A,RAB21,ATP2A2,LPIN2,RPN2,BCAP29,TAP2,ANKRD13C,CYB5R1,AHCYL1,LMAN1,PDIA6,CLN6,HTRA2,ACSL5,ANKLE2,UBQLN4,ATP13A1,ERMP1,SEC61B,TOR1AIP2,TMEM147,PKMYT1,DNAJA1,RAB1A,SERP1,FKBP3,RHBDF2,DDOST,SURF4,SEC61A1,SCAP,CERS6,SEL1L,CANT1,NCLN,ATF6,FKBP5,MBOAT1,REEP4,ABCA1,TMEM33,CDS2,TMX3,AGPAT3,SDF2L1,WRB,DNAJB9,HLA-A,EBP,SPPL2A,SEC24C,RRBP1,SLC35B4,OSTC,CAMK2G,RNF5,TMX1,ELOVL5,MLEC,RHOA,PNPLA8,SPPL2B,YIF1A,HLA-B,PLD3,RAB18,PDCD6,MAGT1,OSBPL8,STX18,PGRMC1,PML,LRPPRC,ASNA1,PKD2,SPCS3,PLOD3,FAF1,ESYT2 |
| 2.373e-08 | -17.56 | GO_NEGATIVE_REGULATION_OF_CELL_CYCLE_G1_S_PHASE_TRANSITION | MSigDB lists | GO_NEGATIVE_REGULATION_OF_CELL_CYCLE_G1_S_PHASE_TRANSITION | 93 | 36 | 17377 | 2626 |
SMARCA4,CCNB1,CDC73,CNOT3,RFWD3,RPA2,RB1,MDM2,PCNA,PTEN,CENPJ,FBXO7,GTSE1,CDKN1B,BRD7,BCL2,CNOT6L,CTDSP2,CARM1,PLK3,BTG2,PRKDC,PRMT2,SOX4,MEN1,RBM38,RPS27A,E2F4,TFDP1,E2F1,PML,PKD2,CNOT6,CHEK2,TFDP2,CDK2 |
| 2.435e-08 | -17.53 | GSE2770_UNTREATED_VS_IL4_TREATED_ACT_CD4_TCELL_48H_DN | MSigDB lists | GSE2770_UNTREATED_VS_IL4_TREATED_ACT_CD4_TCELL_48H_DN | 182 | 57 | 17377 | 2626 |
IMMT,PKP4,NSMCE4A,FOXM1,CHTF18,CENPF,DBF4,LAGE3,COMMD5,PNO1,MBD4,SSR1,TERF2IP,CDKN2C,OIP5,PA2G4,MED8,TIMM23,UCHL5,PPP1R8,GRSF1,TTC9C,EFCAB11,PCYT2,CDC25B,CENPM,PRADC1,UBE2M,GINS1,TXNL1,DDX28,MND1,HMGN5,GALC,NOA1,IDH3A,NSDHL,MYBL2,CCDC34,NUTF2,MRPS14,TMEM201,FAS,OPTN,CDC16,RAD18,DSN1,NSMCE2,PRPS2,MRPL27,H2AFX,XRCC3,DMWD,TSTD2,ESPL1,LRP8,CDKN2A |
| 2.435e-08 | -17.53 | GSE17721_LPS_VS_GARDIQUIMOD_2H_BMDC_DN | MSigDB lists | GSE17721_LPS_VS_GARDIQUIMOD_2H_BMDC_DN | 182 | 57 | 17377 | 2626 |
TMED7,RAB14,RAF1,TOR3A,HNRNPUL2,BRAP,USP39,TMED3,UBE2I,ATP6V1B2,GGPS1,SEC16A,PITHD1,APLP2,ATP6V0B,SMC3,KLF16,PIN1,CAPZA1,ARL6IP1,OSTC,MED22,MORC3,PREB,VOPP1,CSNK1G2,GUK1,PBXIP1,TOP3A,NDUFA7,ANLN,CBFA2T2,MRPS14,SERP1,DHX57,RAB2B,MFN2,TFEB,TMEM184C,DERL1,PDCD6,ORMDL2,NIP7,TOMM6,STK38,PPM1G,EXOC4,AEN,ZDHHC7,CRCP,DNAJC30,CHMP7,PURA,ATP6V0E1,TSEN15,ZC3HC1,NUDT3 |
| 2.465e-08 | -17.52 | apoptotic process | biological process | GO:0006915 | 910 | 199 | 17256 | 2622 |
MAX,DDX47,PDCD6IP,TSC2,THOC1,NF1,TMEM109,XIAP,CSNK2A1,CUL1,UBE2Z,MIEN1,BECN1,MAPK14,BIRC2,CDK5,NEK6,SIVA1,ATG3,ETV6,NOC2L,FNIP2,SENP1,DRAM2,CCAR1,TIMM50,RYBP,BAK1,PLK3,PGAP2,AKT2,MCL1,TOPORS,LRP5,EAF2,BRCA1,DIDO1,MCM2,STK17B,BRMS1,AXIN1,PRDX5,BCL7C,OGT,STK11,CHEK2,CLU,ROCK1,E2F2,TRAF5,RTN3,ZMAT3,SMNDC1,PDCD4,UBE2D3,CLSPN,GADD45G,CDIP1,CIB1,TIA1,MEF2A,CYCS,NOTCH2,NCKAP1,PDCD7,PSEN1,RHBDD1,APOPT1,JMY,CFLAR,RTKN,RB1,TIGAR,DAD1,XPA,EI24,MSH2,DAPK1,ARL6IP1,BCL2,MYDGF,KDELR1,EIF5A,PIGT,NOA1,OXR1,ERO1A,BCLAF1,UBE4B,FXR1,CYFIP2,APPL1,SLTM,RHOB,DAPK3,FAS,FNTA,KPNA1,SIAH2,MAP3K5,TMEM14A,DNMT3A,TRAF7,IFI27L1,RPS6KA1,RAF1,DYNLL1,TPX2,RRAGC,PLAGL2,BCL2L1,IRF3,DUSP22,APP,BCAP31,MOAP1,PDK2,BABAM2,TNFAIP8,SIAH1,RALB,PDCD2,BCAP29,TP53BP2,ATF2,HTRA2,PDCL3,EBAG9,PPIF,BIRC3,POLR2G,TAOK1,CUL3,HTATIP2,MEF2D,CADM1,VDAC1,PPP2CA,DNAJC10,DAP3,HINT1,FASTK,HIPK2,GADD45B,TICAM1,GAS2,MAPK1,EYA2,USP53,BCL2L12,GCLM,NDUFS1,MAGEH1,ANXA6,TMBIM4,CASP6,DAP,SRGN,PAWR,CDK11B,FOXO3,MFSD10,FGFR3,PDCD10,CTNNBL1,PTEN,FEM1B,PACS2,MSH6,PDPK1,TGFB1,TNFAIP3,PRKDC,JTB,RFFL,RHOT1,API5,RHOT2,CDK11A,FADD,SH3GLB1,MAPK3,MFN2,CTSL,PDCD6,BIRC5,PRDX3,ELMO1,E2F1,PML,TMEM219,AEN,HMGB2,DDX5,HRAS,ESPL1,HIPK3,FAF1,IFI16 |
| 2.474e-08 | -17.51 | DDX21 (DExD-box helicase 21) | protein interactions | 9188 | 142 | 50 | 17029 | 2761 |
COX15,NIFK,NOP2,IVNS1ABP,MECP2,SUMO2,CSNK2A1,EBNA1BP2,THRAP3,UBE2I,LYN,RBM4,LMNA,LYAR,PA2G4,CTNNBL1,HUWE1,MCM5,RBM34,ZNF746,EFTUD2,RPL19,TARDBP,ZC3H3,FTSJ3,TERF2,CDC5L,SRPK2,STAU1,ZNF512,RPL6,RNPS1,CUL3,RPS24,BRCA1,SRSF5,MCM2,VDAC1,DOT1L,SUPT16H,C1orf131,SYNCRIP,HNRNPR,H2AFX,RRS1,CDK2,SMURF1,TERF1,GPATCH4,SMNDC1 |
| 2.502e-08 | -17.50 | SMARCAD1 (SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1) | protein interactions | 56916 | 138 | 49 | 17029 | 2761 |
USP7,ARID2,GNE,DHX9,CSNK2A1,SMARCA4,SNRPD3,PCBP1,SF3B2,PCNA,SMC3,ZNF302,MSH2,ANP32A,ANAPC7,SMARCE1,MSH6,HNRNPM,PRPF19,CDC5L,RFC3,PRKDC,MTA2,EHMT1,WDR18,ILF3,ANAPC2,PBRM1,CDC23,RFC2,SYMPK,TRIM28,MATR3,SRSF1,XRCC5,SUPT16H,CBX3,DDX17,CDC16,CDC27,HNRNPR,ZNF689,DDX5,BEND3,RUVBL2,YY1,NR2F2,HDAC2,SSRP1 |
| 2.513e-08 | -17.50 | Papss1 (3'-phosphoadenosine 5'-phosphosulfate synthase 1) | protein interactions | 23971 | 26 | 17 | 17029 | 2761 |
MAGED2,GOLIM4,PNISR,GALNT2,HPS5,DBI,TTC9C,IARS2,KMT2B,SLC38A10,CNOT6,TCOF1,MRPL48,RBBP4,CCNB1,CHMP2B,TFRC |
| 2.513e-08 | -17.50 | GCM_DDX5 | MSigDB lists | GCM_DDX5 | 63 | 28 | 17377 | 2626 |
USP7,HMGN1,MAPRE1,RB1CC1,RAF1,SUMO2,DHX9,BCLAF1,SRSF5,DDX39A,CBFB,EIF4G2,EIF4H,PCBP1,SSR1,HNRNPA2B1,NAP1L1,TIMM17A,SRSF4,TRA2B,YWHAZ,DDX5,RBM3,NUP153,AFF1,TCEA1,PTGES3,HNRNPM |
| 2.658e-08 | -17.44 | nucleobase-containing small molecule metabolic process | biological process | GO:0055086 | 587 | 139 | 17256 | 2622 |
ADA2,COX15,TXN,PPCS,NDUFB6,GNPDA1,UQCR10,NANS,ATP5PF,PARK7,MBD4,IMPAD1,PPCDC,UPRT,NDUFB9,SLC26A2,OGG1,KCNAB2,RRM2,AMDHD2,PRPSAP1,MPC1,STOML2,COX5A,DHTKD1,UQCRH,DHFR2,NUDT11,PFKP,NDUFV2,COX5B,RRM1,RAB23,NDUFA4,COX4I1,CYCS,NDUFS7,NDUFS4,ATIC,CTPS1,MSH2,TPST1,ATP6V0A2,AHCY,CYC1,TSTA3,NUDT4,AMD1,DCTD,PKM,ADSS,MBIP,UAP1,DCK,PRPS2,COX7A2L,ACLY,TBPL1,MDH1,DNPH1,GPI,ATP5F1A,NIPSNAP2,NUDT3,NDUFA5,KARS,UGP2,SUCLG1,GNPNAT1,MDH2,UCK2,OLA1,UCK1,ADPGK,EFL1,SLC35B2,ATP6V1B2,SDHA,FLAD1,DUT,ADCY9,TALDO1,AHCYL1,GPD1L,PDCL3,ADCY7,ENPP4,CGAS,ATP6V0A1,NDUFA7,OGDH,NDUFB1,TAZ,PDHX,HINT1,NT5C3B,GUCY1B1,NDUFA11,MAPK1,NADSYN1,GALK1,NDUFS1,MECP2,GNE,TKT,ABHD14B,ATP5F1B,NEIL2,HDDC2,ERH,GART,NDUFV1,NDUFA2,NDUFB4,FUT8,NDUFS8,NDUFA3,RNLS,LDHB,TGFB1,AMPD2,RHOA,TK1,GUK1,LDHA,NADK2,ADSL,ATP5MF,PDE3B,HSPA1B,ATP5MC3,PARG,COX8A,ACAT1,IMPDH1,NAXE,NDUFS5,PGAM1,PARP10 |
| 2.680e-08 | -17.43 | PINK1 (PTEN induced putative kinase 1) | protein interactions | 65018 | 63 | 29 | 17029 | 2761 |
COPS8,IMMT,TOMM20,RB1CC1,PRKDC,KRAS,MCL1,BCL2L1,TOMM40,RHOT1,RHOT2,KIF11,TOLLIP,MARK2,PARK7,HSPA1B,PSMD2,PSMD1,HSPA4,PTEN,FBXO7,SOCS4,APPL2,PARL,STAT3,UBE2M,TUBB,HTRA2,CDC37 |
| 2.700e-08 | -17.43 | GO_MACROMOLECULAR_COMPLEX_DISASSEMBLY | MSigDB lists | GO_MACROMOLECULAR_COMPLEX_DISASSEMBLY | 178 | 56 | 17377 | 2626 |
CHMP2A,MRPL9,MRPL42,MRPS15,ARID2,MRPL39,GSPT2,MRPS26,KLC1,SMARCA4,KIF2C,CSNK1A1,STMN1,GFM2,MRPL19,MCTS1,MRPL50,KIF5B,KIF14,MRPS27,MRPL34,MRPL54,MRPL48,MRPL40,MRPL21,MRPL11,SMARCE1,DVL2,MRPL32,MICAL3,CFL1,MRPL12,MRPL43,MRPS10,FRAT2,LRP5,MRPL16,ARID1A,CHMP2B,MRPS14,SUPT16H,MRPL2,DAP3,KIF18A,KIF18B,MRPL55,AXIN1,CHCHD1,EIF2D,MRPL27,VPS4A,DVL1,CHMP7,MRPL13,MRPL3,SMARCD1 |
| 2.716e-08 | -17.42 | GSE9650_EFFECTOR_VS_EXHAUSTED_CD8_TCELL_UP | MSigDB lists | GSE9650_EFFECTOR_VS_EXHAUSTED_CD8_TCELL_UP | 187 | 58 | 17377 | 2626 |
PPIB,CMAS,FEZ2,ST13,HNRNPAB,NDUFB6,ANXA6,DAP,PTTG1,CIB1,UBE2Z,BRAP,B4GALT1,RACGAP1,EBNA1BP2,DNAJB1,TWF2,ETS1,MIEN1,REPS1,USP5,GOLM1,VAV1,ATP6V0B,FGFR3,RPN1,MLX,EIF4A3,PHTF1,EFTUD2,MRPL34,FAM89B,HADHB,AP1M1,H2AFY,PDIA6,CDC37,PPIF,EIF3L,DEAF1,PRIM2,TSPAN31,RNPS1,MFNG,TMEM147,USP22,ICAM2,TXNL4A,PRPSAP1,PSMB3,PLD3,STK38,AXIN1,DBI,ATP6V0C,SSNA1,CTSA,RNF14 |
| 2.716e-08 | -17.42 | GSE41867_NAIVE_VS_DAY8_LCMV_EFFECTOR_CD8_TCELL_DN | MSigDB lists | GSE41867_NAIVE_VS_DAY8_LCMV_EFFECTOR_CD8_TCELL_DN | 187 | 58 | 17377 | 2626 |
RMND5A,UBL3,CORO7,CDS2,ANKRD13D,DNAJB2,ZFP91,SRSF6,DLGAP4,BRAP,SMC6,TOP2B,MYO9B,MXD4,DOCK11,ETS1,SYNRG,PDK2,SUB1,ARPC5,RPL17,RCSD1,PIKFYVE,F2R,RLIM,SRSF11,SAMD4B,ELOVL5,ZDHHC18,IFRD1,CYTH1,FAM49B,ZMYND11,BTG2,RDH10,POLR3GL,WBP1,ADRB2,AZI2,HERPUD2,STX16,ARSK,SLC50A1,BSDC1,PHF6,DERL1,MKNK1,TXNDC16,UAP1,KLHL15,MYO18A,SIAH2,WIPI2,MYL12B,ABCA1,TOB1,PDCD4,NUMB |
| 2.716e-08 | -17.42 | GSE22886_DAY0_VS_DAY7_MONOCYTE_IN_CULTURE_DN | MSigDB lists | GSE22886_DAY0_VS_DAY7_MONOCYTE_IN_CULTURE_DN | 187 | 58 | 17377 | 2626 |
SEPHS2,NDUFS1,SCAMP3,NDUFB6,HEXB,LAGE3,NIT2,NENF,SPR,BCAP31,MYL6B,TFRC,LMNA,EBP,SLC31A1,TNS3,CLIC4,IARS,UBA5,MEA1,PIGG,HADHB,SEPT11,MRPL40,TECR,MTX2,GM2A,ALDH9A1,MOSPD1,ACP2,TIMP2,CSRP1,DENND4C,ACSL3,GMFB,PSMG1,TMEM147,SLC17A5,ICMT,CYB5A,PRDX1,PI4K2A,ALG3,ATP6V1D,ATP1A1,SERF2,TIMM17A,CORO1C,SETD3,DBI,MPV17,ACAT1,MDH1,PLOD3,ATP6V1C1,CD81,PFKP,ANXA11 |
| 2.716e-08 | -17.42 | GSE17721_CPG_VS_GARDIQUIMOD_1H_BMDC_DN | MSigDB lists | GSE17721_CPG_VS_GARDIQUIMOD_1H_BMDC_DN | 187 | 58 | 17377 | 2626 |
BCCIP,CTDP1,MMACHC,MRPL9,TMEM203,AGTRAP,RPS6KA1,PIGQ,HNRNPUL2,DHX9,THRAP3,UBE4A,LCLAT1,SDHA,USP5,CDKN2C,EIF2S2,MCM5,BDH1,FIZ1,ZNF746,PPP6C,PDCD2,CYB5R1,SLC35A1,TMEM14C,FGFR1OP2,SMC4,CSTF1,ACSL5,TXNL1,ERMP1,BRD4,NUDT4,PRKDC,RAB7A,PGS1,SUGP2,TYW1,GBA,TOPORS,MTX1,API5,BTBD1,STOML2,ORMDL2,HNRNPR,MAP4,FAM3C,ACLY,SEL1L,ZDHHC7,RNASEL,PLOD3,PPP5C,SLC25A39,HRAS,TMEM33 |
| 2.716e-08 | -17.42 | GSE13411_NAIVE_VS_MEMORY_BCELL_DN | MSigDB lists | GSE13411_NAIVE_VS_MEMORY_BCELL_DN | 187 | 58 | 17377 | 2626 |
TMEM106C,MDH2,RAF1,CDT1,RAC1,HEXB,STARD7,NIT2,SDF2L1,PPP1R16B,FOXO3,PIP4K2A,PABPC4,EDC3,ATP6V0B,MED8,IARS,BDH1,PELO,MEA1,CYB5R1,MRPL40,MRPL48,NAP1L4,MOB1A,ATP6V0D1,UBE2M,PABPC1,TERF2,ABCC1,MLST8,LDHB,CPNE1,POU2AF1,GUK1,PIGT,ZNF780B,MRPL12,NARF,EIF2AK1,HAGH,EIF3G,GNAS,TPD52L2,POLR2J,QARS,GOLGA8A,EIF2D,PPM1G,TFDP1,RBMS1,CTSA,ASNA1,GPI,SPCS3,GALNT10,PGAM1,AP2S1 |
| 2.716e-08 | -17.42 | GSE9650_NAIVE_VS_EXHAUSTED_CD8_TCELL_UP | MSigDB lists | GSE9650_NAIVE_VS_EXHAUSTED_CD8_TCELL_UP | 187 | 58 | 17377 | 2626 |
ST13,ADD1,DAP,XIAP,TIA1,BRAP,B4GALT1,USP39,DNAJB1,TWF2,MAP1LC3B,RUFY1,PIP4K2A,VPS25,ATP6V0B,RPN1,C18orf32,MLX,EXOSC7,PHTF1,HADHB,RNASEH2A,METTL9,FBL,LMAN1,GM2A,RNF5,CDC37,ABCC5,ADCY7,PPIF,ELOVL5,DEAF1,RPRD1A,TSTA3,EMB,RNPS1,SMU1,GLO1,ADRB2,TXNL4A,API5,PRPSAP1,CCT8,RBM38,MAT2A,ANKRD10,MAFK,RNF38,ATP6V0C,GALNT10,ACADM,PSAP,FBXL3,HEXA,EYA2,TUBB,IPO4 |
| 2.716e-08 | -17.42 | GSE19923_WT_VS_HEB_AND_E2A_KO_DP_THYMOCYTE_UP | MSigDB lists | GSE19923_WT_VS_HEB_AND_E2A_KO_DP_THYMOCYTE_UP | 187 | 58 | 17377 | 2626 |
TMEM106C,RMND5A,CUTA,RRM1,HAUS4,FKBP2,OAT,TCF19,CPNE3,USP5,MBD4,DNAJC8,MCM5,TBC1D14,PRC1,MSH2,SUCLG2,TAP2,RNASEH2A,SAP30L,ARL5A,IMPA2,CGGBP1,TACC3,TMEM160,GPX4,SRPK2,TK1,CDC123,MAP4K4,EMP3,ANAPC2,CDC6,AURKB,BRCA1,WBP1,ICAM2,CCNF,RFC2,PSMB9,BTBD1,ASF1B,CYB5A,RPA1,GALNT2,JAK1,ACYP1,EXOC4,OGT,PGRMC1,BAZ1B,CDK2,SNX14,ZMAT3,TUBB,CSNK1D,SSRP1,SNAPIN |
| 2.717e-08 | -17.42 | brain | COSMIC cancer mutations | brain | 16658 | 2527 | 17385 | 2587 |
HECA,ZBTB10,ABCC10,HEXB,CCNL2,FBXO22,EEF2K,THAP4,RAD23B,ATP13A3,DNM2,ZNRD1,FTSJ3,USP34,CCDC57,ERCC1,NRAS,EHMT1,KIF15,HNRNPF,WDHD1,MIER2,DIDO1,MCM2,RAB22A,SMAD2,MID1IP1,RPS27A,MYO18A,OGT,MPV17,COX5A,SMAD1,ZNF75A,ANXA11,SLC25A33,SEC61G,GGA1,MUM1,CCZ1,TRIO,CUTA,RAB23,KCTD17,HAUS4,EIF2AK4,APH1B,PARN,CDC73,MYL6B,ATG4A,TMEM179B,PDXP,SMC3,GEMIN4,MVP,NUP85,PPP6R1,PABPC1,NSUN4,PPA1,IFRD1,AGGF1,FOXK1,RBM42,GTPBP4,MAP7D1,MRPL16,ELK1,EIF4H,RDH11,MAGED2,KPNA1,ETS2,TYW5,WIPI2,RUFY3,PDLIM5,ACSF2,RHOG,EXOC3,STARD7,VTI1A,C5orf30,INO80E,SLC35B2,LCLAT1,RCOR3,CPNE3,KIAA1147,RBM23,ZNF420,AHCTF1,TBC1D22A,TBC1D14,GMEB1,NSFL1C,SEPT11,ZNF226,GPD1L,ZC3H3,ARL5A,PDCL3,SNX8,ERMP1,EID1,IDH3A,POLR2D,HTATIP2,MEF2D,TMEM147,GSTCD,TANC1,MAT2A,VPS26B,NSMCE2,CORO1C,CAMKMT,PPP5C,PITRM1,TUBB,COMMD10,ZNF445,SRSF6,HABP4,CCM2,FLOT1,BTN3A1,ATG2B,ABHD14B,PPP1R3B,ZBTB45,HUWE1,ZNF260,NAA50,ANXA5,LTN1,UBE3B,NAP1L4,ZNF710,ST8SIA2,RPL22L1,MED22,SPTAN1,STAU1,DDX24,TACC1,MRS2,LDHA,HEBP2,LLPH,RAB3IP,TTC33,PICALM,SH3BP5,SLC19A1,ACOX1,FAM3C,AEN,PARP10,YWHAH,THAP5,GPATCH4,FAM129A,TRIM11,YTHDC2,SNX15,RBM8A,ENSA,NENF,SND1,RUFY1,TRIM65,ZER1,PRNP,KRR1,RAB8A,NUP210,NT5DC1,NOC2L,EIF5,TACC3,RYBP,VPS13B,PTPN18,MIOS,SNRPB,MBLAC2,CDC6,UTP3,PBRM1,ODC1,USP21,TRAM2,FBXO28,BCL7C,ARRDC1,ADAM9,DVL1,NUMB,ZNF564,FUBP1,C1orf74,CTU2,PARP12,ZCCHC9,CENPF,LAMTOR3,CHCHD2,NCKAP1,LYRM2,RSAD1,TNS3,SUB1,RINL,SSBP3,KIF13B,MBD2,XPA,AHCY,RBM3,GLE1,MRPL48,LRSAM1,HDHD2,NTPCR,NSDHL,AMD1,CAMSAP1,ZNF761,METTL22,ICAM2,STYXL1,APPL1,BBS12,ANKRD46,RXRB,SDHB,PCM1,GALNT2,TMEM168,NLRC5,RUVBL2,BTBD10,MYO9A,CCNB2,USP7,GLT8D1,RPLP2,SUCLG1,ARID2,TMX4,SLC2A1,ATP6V1B2,PCBP1,LYN,BCAP31,VAV1,TMEM69,MRPL50,PSMA6,ZNF473,ZNF302,BRPF3,TARDBP,BCAP29,CTDSP2,PRPF19,PPIF,KDM3B,MND1,CLCN3,BIRC3,RAB7A,ANKRD33B,PPIE,CHMP2B,VDAC1,EIF3H,TMEM201,GLOD4,IDE,DHX16,UHRF2,CHMP4B,XRCC3,PARD3,BCL2L12,C19orf53,MCM10,KLHL21,PDAP1,CDCA8,TMX3,ARF1,SLC12A9,TUBGCP2,DNAJB9,HOMER1,POLR1B,RNF5,RBM15B,PPAN,RHOA,RPRD1A,BTAF1,TOP3A,ARHGEF12,PCGF1,DDX23,RAB18,CACNB1,TRIM26,PDCD6,ATP6V1D,L3MBTL3,FAM110A,NEIL3,CTBS,BBX,IMPDH1,TAF12,NR2F2,PGAM1,HIPK3,IFI16,TXN,NUP188,H2AFZ,PNISR,TMEM203,PRKCSH,USP39,UBE2I,PARK7,SLC25A37,ASPHD2,ZNF428,RAB4A,TRA2B,SUCLG2,TAF5L,SMARCE1,ZNF800,CDC5L,ZNF524,SGCE,OSBP2,NSUN2,USP22,CLNS1A,EIF3A,ZMYM3,DOT1L,IWS1,ANKRD10,WAS,KIF18B,TPP2,C1orf109,ZMAT3,B4GALT2,PRPF38B,RECQL,C9orf78,EWSR1,GADD45G,RRM1,ACAP1,B4GALT1,CYCS,FAM136A,SUPT7L,TMEM165,CNOT3,NPLOC4,WDR48,SPAG5,RTKN,CEP104,EXOSC7,KLHL5,LRRC8D,PPP4R1,MSH2,PIGG,OSTF1,FBXL7,MRPL40,TNRC18,SYTL3,FAM171A1,APOL1,EIF5A,GCC2,PRIM2,ELL2,RDH10,MFNG,RPS24,GORASP2,CAPZA2,ADRB2,CCT8,MTR,PHF6,PFDN5,SLCO4A1,TTC13,GOLGA2,RBMX,MED15,PIAS2,APPL2,SAMD8,CDKN2A,NUDT3,ZNF511,ATXN3,RAF1,KIAA0232,C2orf49,EPM2A,CD320,CCNA2,MTMR4,BRI3,TP53BP2,AQR,RBM12B,ILKAP,CDK12,SAP30,BRD4,DRAP1,NARF,LRRC8A,ELP4,ABHD11,PKMYT1,ASB13,SERP1,TRIM28,SUPT16H,EIF3K,CHMP4A,ATF6,XRCC4,ADAM23,PRPF4B,NDUFS1,DEPDC1,MECP2,SECISBP2,HMG20A,WWP2,SLC25A36,JAKMIP1,CCNK,DNAJC8,AXIN2,CITED2,JMJD4,ANKRD37,KAT2A,TMEM126B,RABIF,ADSL,PACS1,BMS1,KCNQ1,ARSK,MACF1,KIF11,COMMD4,KLF6,SMAP2,FADD,SH3GLB1,MYO1F,CBX3,TMEM127,INF2,PPP1R11,DUSP11,DDX5,WDR62,TAF6,ESPL1,PURA,DDB1,DEF6,FAM83G,IPO4,UBL3,NAT9,PIGM,LYRM4,GPR132,UBE2Q1,PTP4A3,BRIX1,MRPL19,ZNF696,SF3B2,PCYOX1L,CDC42,SYNM,GOT2,JAZF1,HADHB,RPF2,SLC35C2,CNNM3,CARM1,SRPK2,WDR41,LARS,ZCCHC10,CCDC138,LRBA,TMEM216,SUMF2,KMT2C,OGFR,PRPSAP1,ASF1B,RPL37,MAN2A2,EIF4ENIF1,NIP7,U2SURP,MIA2,ZNF268,VPS4A,ATP6V0E1,PPP1R2,PM20D2,XPNPEP3,RGS2,LYAR,FAM89B,POLR2I,TRAFD1,SUGP2,GBA,SYVN1,DAPK3,ARHGAP15,MASTL,UAP1,NFIL3,FN3KRP,YWHAZ,CTSA,TMEM14A,TOB1,TSEN15,ADNP2,TCF12,PRKAB1,MDH2,SMARCA4,ORC1,RRN3,UBXN2A,IARS,CD3EAP,KIF14,EXOSC1,CS,CLTB,DNAL4,CSTF1,POU2AF1,UBQLN4,NXT1,HPDL,PGGT1B,SELPLG,SMU1,ATXN1,GLO1,OGDH,BICD2,CADM1,EDEM2,HERPUD2,TOLLIP,FANCE,MBD3,PDHX,RPS9,ALKBH6,SURF4,DUS3L,ARNTL,ANP32E,FKBP5,TMEM101,CCDC125,ABCA1,PDCD2L,GCLM,RAE1,DCTN2,NUP54,CHIC2,PAWR,MXD4,DCUN1D4,PIP4K2A,XPR1,FERMT3,KIF5B,KLHL20,SEC24C,RRBP1,ARHGEF2,ANP32A,LDLRAD3,C12orf75,STAT3,MYO5A,NIPAL3,AMPD2,TXNL1,PHF20L1,DCAF6,FAM49B,TMEM39A,ATP2C1,RFFL,COG1,RCOR1,PRMT2,TFEB,LEMD2,UPF1,ELMO1,ZC3H7B,DTX4,ZMIZ1,TERF1,HRAS,CCDC93,FGFR1OP,TMED7,PIGQ,AGPAT1,CNTROB,PPP1R16B,MIS12,GSDMB,TTC9C,PDS5B,NUP153,SENP1,PGAP2,TMEM115,PLEKHM3,DCUN1D5,PLEKHF2,BRMS1,PWWP2B,TRIM47,WDR11,AXIN1,SMG9,TRIM52,LONP2,NDUFV2,PHF23,CERK,SLC4A2,EZH1,ITGB5,LMNA,MCTS1,DDX56,EIF2S2,SLC38A5,FOXN2,CARS2,PRRC2A,C16orf72,RB1CC1,ZMYND11,PGS1,MYBL2,UHRF1BP1,SRSF5,MPG,MATR3,CYB5A,NCDN,POLR2J,SETD3,TEX30,PTAR1,CNOT6,NDE1,EGLN1,ZNF207,ANKRD27,PPP1R37,ABCA3,SARNP,IVNS1ABP,MON1B,RMI2,TMEM97,NIT2,NUF2,ZNF267,TCF19,TMEM161B,KTN1,APP,PRKD3,CLUAP1,ATP2A2,UTP18,GRSF1,DUT,ZCCHC2,ANAPC7,RNF19A,FAM76B,CLN6,TMEM9,GCC1,RNF169,ADCY7,ATP6V1G1,ENPP4,RNPS1,CDCA2,FKBP3,GPR137,DDX17,CHCHD3,PEX5,CDC16,HIPK2,MBOAT1,TICAM1,PDXK,ZBTB11,ANXA6,TMBIM4,GMCL1,UBE4A,IL21R,ETS1,WRB,ZNF92,PNO1,CAPN2,ADD3,SUV39H2,TTLL12,TPCN1,TMX1,HNRNPM,LYPLA2,MFSD12,LDHB,PPP3CA,NUDT8,POLK,JTB,EMP3,MTMR12,ZP3,PDE3B,KIF18A,CCDC6,WNT5B,MAPK6,C4orf46,LY75,SLC25A19,RGL1,PSAP,WDR76,IGBP1,FAF1,SNAPIN,COX15,THOC1,AGRN,GNPDA1,GPBP1L1,PPP1R15B,CSNK2A1,EBNA1BP2,GIT2,BIRC2,ATPAF1,DLG5,ABL2,XRCC2,ZFYVE27,MCMBP,PTPRK,CDC37,METTL1,SP3,EXOSC6,HARS,GMFB,ESYT1,ANLN,RAB5B,RHEB,DPYSL3,TBC1D17,TIMM13,CDCA4,TONSL,NRM,NAGLU,ACTB,ZNF45,TMUB1,CTCF,ASAH1,DOCK11,CRLF3,ASXL2,LRRC14,NUS1,SLC27A4,AFF1,MDFIC,MAML1,CYTH1,NQO2,UTP15,EIF2AK1,EIF4G2,ZDHHC3,MOSPD3,ITPRIPL1,CDC27,SNAP23,TBPL1,PRMT7,KCTD7,NDUFA5,CYLD,UGP2,DYNLL1,COPE,HCFC1R1,ZADH2,GGPS1,RPAIN,RAD23A,ATP6V0B,PDK2,STRBP,DUS4L,MRPL34,PDCD2,SAP30L,CLPTM1,SLC39A9,RPL29,RPL35,BTG2,DNAJC9,FRAT2,MTMR6,NFATC2,KDM1B,ARL5B,USP36,CCDC127,MRPL2,ATP1A1,CLK3,MAFK,PSMD3,NDUFA11,CEP55,ZNF436,DNAJC17,NCOA1,SLC25A39,ZC3HC1,ZNF146,ATXN7L2,CDC40,SMAP1,GOLIM4,RRP15,DAP,GNE,SMC6,ARFIP2,NKRF,CHAC2,BZW2,WRNIP1,SS18L1,CENPM,PTGES3,CAMK2G,MLEC,ZNF202,PPWD1,FAM50B,RHOT2,NEU1,TPD52L2,GOLGA7,TWSG1,GLG1,PGRMC1,FAM126A,RPS6KC1,UBE2C,PPCS,NDUFB6,TMEM41B,ZDHHC8,PLXNA1,CCNB1,SLC20A1,COMMD6,ABHD14A,POLR3K,C14orf119,ASAP2,SNUPN,CNPY4,PLCL2,TFG,SEH1L,ATG9A,PBK,MKI67,DDX20,AMDHD2,GALNT7,SLC17A5,CCNF,FOXRED1,RBM47,PTER,WDR4,DHTKD1,TRAF5,HDAC2,PWWP2A,HSPH1,MAPRE1,CHTF18,ADO,KIF23,SLC35B1,NOTCH2,PMF1,JMY,FKBP1A,SLC31A1,SNX18,ATIC,ATP6V0A2,PIKFYVE,RNF135,LPCAT1,EEF1D,TMED2,PHF10,FTL,DDX28,ZNF84,SIGMAR1,PIP4K2C,RIT1,PLEC,KDM3A,SF3A2,FAS,EPRS,ZNF777,TMEM54,QARS,PPP3R1,TCOF1,NRBP1,CABLES1,DNMT3A,RWDD1,CKLF,TRIP10,SF3B1,RPS6KA1,SUZ12,CAST,RAC1,GPR89A,OLA1,SNN,GNB2,FLAD1,APLP2,KDM2A,TNPO2,CDKN1B,TALDO1,GPX4,ATP13A1,RFC3,MAPRE2,ERF,CUL3,SLBP,KIAA1586,H2AFV,POLG2,GAR1,PSMB9,DHX57,NSA2,HSPA4,MRPL55,JAK1,TBL3,SEL1L,H2AFX,KLHDC4,B4GALT3,PDCD11,ATMIN,POLQ,POU3F2,OTUD5,NCOR2,ANKRD13D,PKP4,SCAMP3,BABAM1,CDCA3,SLC25A12,BLM,TMCC3,GTF2F1,RPL17,CRAT,AHSA1,PRC1,UPF2,COPS7B,SLC38A10,CNOT6L,CNPY3,UBE2M,IFT46,TMEM160,TSHZ1,ZFP64,DENND4C,DENND1B,WDR18,RPL8,ILF3,LRRC1,RHOT1,TSR2,MARK2,ECH1,PRDX1,PLD3,NUCB1,GNA12,FBXO21,C1orf131,PRDX3,PFDN4,HNRNPH3,STX18,TFDP1,KHSRP,ASNA1,CPEB2,SSSCA1,BYSL,VPS29,S100PBP,MIB2,IER2,PTMS,NOP2,UBN1,DCAF15,NF1,FLYWCH2,ALKBH5,MOGS,TAF6L,MAPK14,BECN1,SNAPC4,RNF103,BCAT2,MBD4,C18orf32,METTL14,IMPAD1,ZNHIT6,RCSD1,PHTF1,SRI,KIF22,ZBTB22,NFU1,OGG1,TRIM14,ELOF1,COPS8,FYTTD1,TRIM8,RRM2,SOX4,ABHD5,UBTF,CXXC4,PAF1,UEVLD,SPATA2,PQBP1,IARS2,ATXN2L,GALNT10,STARD3NL,RPS15,PIGN,AGTRAP,CIB1,XPO7,SRRT,ZNF449,CAPZA1,GLTP,BCL2,KIFAP3,N4BP2,HP1BP3,VOPP1,THNSL1,ISG15,CAND1,GNAS,TSC1,RBM25,CDCA5,ZFP90,NANP,RBBP4,ZBTB24,SMARCD1,MBD1,WASF2,MMACHC,TOMM20,IFI27L1,GNPNAT1,MPHOSPH8,HNRNPUL2,CHD1,MEAF6,C2orf68,CCDC50,AKAP8,PARL,RPN2,CHTOP,FAM3A,F2R,TMEM14C,SCYL3,ABI1,HTRA2,MOSPD1,RLIM,FAM172A,ZNF500,PSMB7,NLN,WIPF1,BOLA1,BUD13,NDUFB1,PEF1,EIF3G,BTBD1,TAB2,CHCHD1,TULP3,WDR59,CANT1,SCARB1,GAS2,USP11,SMURF1,PPP2R2D,TSPAN5,CDS2,MAGEH1,MRPL42,EYA1,CDK2AP2,MRPS26,LETMD1,KLF13,HDDC2,RGS1,MAN1A1,FBXO5,GART,TANK,BRD7,MRPL11,SAMD4B,ZDHHC18,GTF3C6,POLR3GL,WDR81,MEN1,ZNF407,MFN2,COX8A,ZRANB2,SRSF3,MBD6,ATP6V1C1,IDH3B,TATDN1,TSC2,LACTB2,CMTM6,RBM4,ZNF275,RPL23A,CDKN2C,NAPG,USF1,MECR,AP1M1,UPRT,CRY2,ECD,RNF26,TIPARP,LRRC59,ANKRD9,RHBDD2,MGAT5,BAK1,ZNF559,RHOBTB3,GABPA,WBP1,NUTF2,ARF4,GINS4,KRIT1,BOLA3,AHNAK,RAD18,PDRG1,RNASEL,CHPF2,OAZ1,PDCD4,SMNDC1,NXT2,HIVEP3,KIAA0100,CLSPN,RHOC,DHX9,PDCD7,PSMD9,HAUS2,COPB2,TFAP4,CD59,RNFT1,RIMS3,MEGF8,EFTUD2,FBXO7,CPSF4,MRPL21,PHKG2,LUC7L2,SRSF11,EIF3L,MTA2,TYW1,USP10,ITM2A,SSR2,BCLAF1,MTX1,SFXN5,FNTA,PDLIM1,TXNDC16,TMEM159,MRPL3,ALS2,FAM72A,TRIM41,KARS,NQO1,POC1A,ANK3,PTTG1,TPX2,TBC1D13,DAZAP2,STMN1,GLRX3,C19orf48,REPS1,ABHD16A,FBXL6,SH3BP1,MTA1,UBA5,CLCN6,INTS12,C8orf59,RPRD1B,CGGBP1,CPNE1,SEC61B,POLR2L,FAM118B,GOPC,E2F3,CIRBP,RPL38,CRNKL1,PFKFB3,GORAB,RAB1A,GIGYF1,TMEM184C,PPP2CA,KIF2A,CCDC14,LSM6,RNF38,SNRPG,DMWD,USP13,ZFP91,TRMT6,IP6K2,WDR5,SLC25A43,PMVK,IFT27,NEIL2,RRP36,SRXN1,RPA2,PSMD2,CLIC4,PDCD10,ITGB8,CBWD2,COQ4,ARF5,ARHGEF1,FBXL19,GTF2H2,TTPAL,UTP20,MAGT1,GPS2,DBI,MRFAP1L1,SSNA1,CD81,TMEM131,WDR13,FANCI,PAPOLA,CREM,FANCL,TET3,GLIS2,IL6ST,INTS1,POP7,SLC44A1,MTPN,ASB6,PLK1,RPP25,CELSR2,SEPT9,RBX1,APH1A,RAD51AP1,CKAP2L,PSMG1,UBE2V1,IL12RB1,EAF2,KRTCAP2,LUC7L,LSG1,NECAP2,C1orf122,TRIM4,ALG3,AGPAT2,CHD3,ZNF367,E2F4,PRPF4,KPNA2,BEND6,CLN3,DNAJC30,FAM208A,NGLY1,POT1,MYL12B,CCDC137,RMND5A,HJURP,PHB2,FAM53C,DNAJB2,NKD2,SDC2,KLC1,CDK13,ADCK5,COX4I1,RAB6A,DNAJB1,ARID1B,C1GALT1,MLX,UBE2Q2,CCP110,ZNF746,ARL6IP1,CTR9,NIPSNAP1,ABHD2,DCAF8,ACSL3,LDB1,MAP4K3,ARMC8,RBM38,IRF5,NMT2,RPL36,HAUS8,MBIP,ORMDL2,COX7A2L,ZDHHC7,FAM122A,SIL1,DTD1,UNC13C,BCCIP,SART1,TRAF7,NDUFAF2,TOR1AIP1,ZNF416,LAGE3,TM9SF3,ZFYVE21,RRAGC,ZNF121,OIP5,NRF1,WDR44,PIN1,PPME1,EFCAB11,RPAP1,CABLES2,TOP1MT,LMAN1,AHCYL1,STRAP,SPSB3,ZNF583,SNX25,ARHGAP17,POLR2G,ZNF780B,PPT1,NUP155,DCLRE1C,MRPS14,RHBDF2,SUGP1,RBL1,FASTK,UBXN2B,STK38,AP1S1,SPRYD4,SLC22A23,H3F3A,CHID1,SMAD4,RAD51D,SLC30A9,NADSYN1,UNK,CMAS,HMGN3,NCAPG,SCYL2,FZD6,HERC3,GTPBP3,CTSS,ORC3,RNLS,YTHDC1,ACP2,CSRP1,HMGN5,METTL5,ABCF2,TUFM,RANGAP1,PNPLA8,HAGH,API5,ZFR,SEC23IP,E2F1,USP20,TMEM219,RBPJ,MAX,PDCD6IP,LUZP1,GXYLT1,ADAM10,CXXC1,TSC22D3,AP3M2,CUL1,GYG1,NANS,OAT,MYEF2,ANKRD26,PA2G4,NOL11,FIZ1,ZNF200,MARCH2,SLC26A2,SRP72,KLF10,LACTB,RFC2,CBFB,RAB2B,PRIM1,MAP3K4,HHEX,RPS14,LUC7L3,MAP4,MRPL27,BTF3,PTPDC1,CCDC59,NMD3,PTOV1,COX5B,DNAJC5,SCOC,DHPS,POLR2K,ANKH,PRKAA1,VAV2,C16orf87,GSPT2,DLGAP4,TATDN3,PXMP2,PRPF39,PSEN1,ZNF79,PDXDC1,VPS25,NDUFS7,YY1AP1,C12orf10,FAM192A,RPN1,LHX8,ARPC5,ZNRF2,DAPK1,TPST1,PIK3IP1,CYC1,SOCS5,FDFT1,PIGT,WDR1,EMB,ZNF574,C1orf35,EXOSC9,ARID1A,PTTG1IP,C9orf40,FXR1,GOSR1,MAP2K2,TWISTNB,AKAP1,XRCC5,HMGN2,PI4K2A,CAT,SEC31A,DERL1,MTHFD2,HSPBP1,CEBPG,ARAP1,FAM83D,USP32,CABIN1,SMPD4,GPI,CYTIP,TP53RK,REPS2,RAB11B,UROD,SLC39A13,POMP,BCL2L1,NUDT19,DECR1,RALB,SIAH1,LPIN2,ADCY9,SOCS6,MRPS27,TTC3,RNASEH2A,CFL1,ANKLE2,CDC123,OAF,VDAC2,EDF1,ERC1,EML4,AMZ2,ANKZF1,ZNF282,RAD51C,DSN1,DDOST,HINT1,DGCR8,SAFB,HAGHL,LMBR1,FTSJ1,RWDD4,NCLN,BEND3,EYA2,DYNC1LI2,B4GALT5,SLC41A1,MANBA,TKT,FAM76A,CBLL1,ARGLU1,LANCL1,POFUT1,FAM8A1,HEATR5B,HLA-A,EBP,RFWD3,NDUFA2,FUT8,BTF3L4,PTPN11,MRPL54,FEM1B,RPL19,CNN2,NDUFA3,MTX2,MSH6,PDLIM2,LONRF3,RFXANK,FBXO9,GUF1,RPL32,ZHX1,NDUFS5,WDR91,GPR89B,HIGD2A,ZBED3,RORB,POLA2,ZNF76,MTX3,COPA,UQCR10,HMGXB3,PHRF1,ABCB10,COMMD5,MAP1LC3B,DST,SIVA1,RAB35,GPATCH1,TCEA1,DRAM2,DEAF1,SNRNP200,NCK1,LAP3,VHL,SREK1,ARHGDIB,PITPNB,HSPB11,BRWD1,PPM1G,SH3GLB2,CRCP,BAZ1B,ACBD4,CAB39,STK11,CLU,CHEK2,ZSWIM3,TSTD2,CHPT1,MRPL13,DCAF5,CAPN1,UBE2D3,NSMCE4A,PPP1R12A,ZCCHC8,GORASP1,UBXN1,NACA,PCSK7,RPL15,THRAP3,TTF1,QSOX2,PRPF18,NUP205,CHKA,DTL,MED10,ZRANB1,MCPH1,SLC12A2,ATP6V0D1,CSNK1G3,CREG1,NUDT4,RPL6,VKORC1,SLTM,EVC2,KLHL15,SIAH2,SLC16A1,EHD4,SNRNP70,C11orf1,APOL2,N4BP2L2,SNX27,CHMP2A,CORO7,FEZ2,UCK2,PMS2,UCK1,CLCC1,EXT2,MXD1,USP5,HNRNPA2B1,SAP130,NVL,PPP6C,CYB5R1,ZNF770,EBAG9,RNF25,PCGF6,METTL2A,FAM72B,PON2,HNRNPR,STAT6,HPS5,MAPK1,BRD9,TMEM33,NAT14,DNAJC2,TRIP12,SHPRH,SCYL1,VPS45,MYO9B,GFM2,SPPL2A,FASTKD3,FGFR3,MZT2A,PPIG,ZDHHC13,TMEM99,H2AFY,ATG13,NDUFS8,ERI3,FBL,SLC35A1,FRMD8,MICAL3,TGFB1,B3GALT6,ELOVL5,HEMK1,TIMMDC1,HELB,PSPC1,MIER1,SCFD2,NDRG3,ARL17A,CDK11A,MTMR3,MEGF9,ACAT1,CENPT,PLOD3,RAB3IL1,ZSWIM6,RAB14,ADD1,MRPS15,KDM4A,XIAP,DHX8,GLUD1,ANKRD23,PABPC4,CALM2,CDK5,PSMD1,NEK6,NSRP1,RABGAP1L,SRSF4,FNIP2,KCNAB2,PCBP2,MLST8,PLK3,ZNF672,HSDL1,MRPL43,TOPORS,MCL1,SMC2,PPFIA3,ICMT,SLC50A1,STOML2,LIMK1,ZNF689,PRDX5,ATE1,MLYCD,ATP6V0C,ST3GAL2,FBXL3,TFDP2,E2F2,PFKP,AAAS,DDX42,SSRP1,MRPL9,MRPS2,STRN4,TOP2B,ZNRF3,TMED3,DDRGK1,RAVER2,GNS,INTS7,INPP5A,MCM5,PHF14,ZNF326,UBE2QL1,NAGPA,TIMM8B,ETV3,TSPAN31,DHX29,TEX10,MAN1B1,RPS10,CBFA2T2,ABCF1,RHOB,LRRC14B,DTWD1,PTPRF,SCARB2,OSBPL11,CCDC86,DUSP3,SLAIN1,MDH1,HEXA,RNF139,SNX14,ZNF296,TRERF1,UBR2,CHD1L,ACTR3,WDTC1,MYH9,CREBL2,NIPA2,PRKACA,SAFB2,ANKIB1,STAM,ARL6IP6,RAB21,SP100,ZKSCAN1,DDA1,NUP107,ANKRD13C,MAVS,CEP63,TMEM136,RBM15,ATF2,DCTN1,SHOC2,PSRC1,MAP4K4,WBP2,ATP6V0A1,NUSAP1,NDUFA7,DNAJA1,TAZ,C19orf54,TAF2,SEC61A1,WDR7,RPLP1,CBLN2,RBMS1,FUS,GEN1,LRP8,COIL,LRCH1,GALK1,ZNF786,RPS2,SESTD1,TRAK1,JMJD6,SIKE1,AKT1S1,KRI1,FBXO3,ERH,GATC,PPP1R8,PRDM4,GTSE1,GEMIN6,DCP1A,SGCB,S100A6,IMPA2,NUDC,PDPK1,TK1,GUK1,TNFAIP3,GALC,ZNF512,KIAA0930,MRPS10,DDX39A,RPA1,ZNF180,ZNF862,KEAP1,POLE,TATDN2,PITX1,CAPN7,LRPPRC,PML,HMGB2,USF2,ANAPC4,SRM,DDX47,MCCC1,CDC42SE2,S1PR2,CDIPT,SEC16A,SSR1,LIN9,PCNA,ZNF639,TRMU,PIK3R2,ETV6,PPCDC,TXLNA,FAM86C1,MYBL1,MRPL32,CCAR1,ABCC5,PBXIP1,BAZ2A,TLK1,MRPL12,EZR,LNX2,LRP5,BRCA1,PRKRA,STX16,EPB41,OPTN,SEPT1,SOCS4,QRSL1,PIEZO1,OSGEPL1,GLCCI1,NUDT11,GEMIN7,SEPHS2,LZTR1,RACGAP1,PPP3CB,B4GALT4,RLF,RAPGEF6,SNRNP25,RB1,VASP,MED8,VMP1,PPIL2,MEA1,TIMELESS,AHDC1,ALDH18A1,TMEM8A,ABCC1,PREB,TRAPPC9,AACS,MEMO1,KRAS,RTF1,UBE4B,NFATC2IP,LY6E,ARPC1A,ZNF174,PSMC4,GOLGA4,PALB2,SYNCRIP,PRPS2,NIPA1,TIGD2,RNF114,FOXM1,MRPL39,XAB2,SUMO2,DUSP22,COMMD8,RPL11,CSDE1,MDM2,CORO1A,MINPP1,METTL9,POC5,DVL2,GM2A,PSMA8,COQ10B,CPOX,TIGD5,SLC26A6,CYP20A1,PRPF3,TXNL4A,RPSA,SRSF1,DNAJC10,SCAP,ZNF700,PLEKHG4B,TIMM17A,FAU,LTA4H,AP2S1,USP53,INTS2,CTDP1,MIF4GD,CDT1,ARID5A,SUMF1,GGA2,AP3S1,CSNK1A1,RMI1,TFRC,PTPN2,STARD9,IRF4,GSTK1,NDUFV1,SLC1A4,CWC27,SLC35B4,DDX31,ABCD1,RPAP3,CNTN5,SNX2,ZMYM5,CCDC34,CHCHD6,BSDC1,KPNA4,CDKN2AIPNL,FBXO41,BIRC5,TFE3,SNAP29,CDCA7L,PKD2,ACADM,CHMP7,SAT2,GCSH,ZNF496,TMEM109,TAP1,NHLRC3,IKBIP,EIF1B,ELMOD2,KIFC1,DBNDD1,CYB5RL,PARPBP,RNASEK,CDC25B,PRADC1,DNMT1,NOL12,ORAI2,USO1,AKT2,NOL8,GNG7,AURKB,MCFD2,SLC25A5,ZFAND5,MAK16,STT3A,TMED10,PSMD8,EIF2D,ITGB1,PTPN7,UQCRH,RRS1,ARRB2,RTN3,ZNF598,SVIP,DDX58,WSB2,PPIB,MUT,GMFG,HLA-E,NDUFA4,MAN2B1,METTL3,CFLAR,NDUFS4,RNF121,MEX3C,KLF16,HDAC7,DAD1,BDH1,PCYT2,GNAI2,ANKHD1,MORC3,TERF2,KCTD20,SEPT8,DCTD,PKM,TOMM40,PATL1,ADSS,SERTAD2,SERF2,ZFP92,NSF,DCK,ERGIC3,ACLY,LPCAT4,VCPIP1,YY1,PPP6R2,PPP6R3,MAP3K5,RNF14,CDK2,ZC3HAV1,SYS1,ZBTB37,URB2,EIF3D,MAGED1,KLHL18,ADPGK,SLC25A44,AP1B1,SDHA,PAIP2,PHC2,CRKL,TERF2IP,MOAP1,CYHR1,ZNF75D,SHC1,UCHL5,NAA35,TMBIM1,CCT2,CDKN2AIP,MKLN1,HMGN4,LYRM1,GALK2,CDC23,SHCBP1,AP4E1,PRDM11,VEZF1,PPP2R5A,ACYP1,STAT1,PPA2,TRIM32,RHEBL1,C1orf112,TCF3,MRI1,BRAP,AGPAT3,MYNN,SDF2L1,SPR,RAB11A,REEP5,FOXO3,MAD2L2,CCDC28A,PIP5K1C,RBM17,MAT2B,PTEN,CENPJ,TAGLN2,OSTC,CREB1,PACS2,NCOA2,SMC4,RNASEH2C,NEK7,NET1,PARP4,TBRG4,ANAPC2,RPL27A,YIF1A,SGSH,HGS,TTLL4,SLC38A7,MFAP1,CCDC69,BRWD3,ESYT2,SKA3,NPHP4,UBE2E2,HNRNPAB,PLXNC1,ST13,TMEM184B,DNAJC24,ZNF107,SLC29A1,KIF2C,AGFG1,SIRT2,FKBP2,USP48,SNRPD3,UBQLN2,CUTC,EDC3,UBLCP1,ZNF804A,RAP1A,THADA,EIF4A3,AP3S2,ATG3,DPYSL2,PPP1R12C,AKR1B1,NDUFB9,JOSD1,RP2,TTC4,TECR,ARID4A,FGFR1OP2,TIMM50,TDP1,DPM1,FOPNL,SLC16A7,WDR82,SLC25A22,STK17B,DHX15,CHAF1A,GEMIN5,COPS6,SASS6,RPS26,PSMC1,SLC12A7,TBC1D12,TM9SF4,ZNF768,UFC1,MED13L,TIA1,MEF2A,EPHX2,PITHD1,RHBDD1,NFATC3,BANF1,BUD31,ZNF335,YBX1,KNTC1,ACAD8,UBE3C,ZNF189,ALDH9A1,KDELR1,TSTA3,CIC,OXR1,PSMA1,TMEM241,SEPT7,NAP1L1,ODF2,EXOC4,KIAA1328,NUP62,PITPNA,NAA20,PTDSS1,MZT2B,PDSS2,C7orf26,TMEM106C,IMMT,ASH1L,CHERP,WDYHV1,PLAGL2,CHKB,IRF3,TWF2,PAIP1,ANKRD28,ANKLE1,FARSA,SAR1A,SCAMP4,APOOL,PDIA6,ACSL5,TOR1AIP2,AZI2,GFER,RAD54B,DAP3,TMEM41A,ZNF317,GADD45B,AKNA,REEP4,CBX4,MIF,KIF3B,GOLPH3L,SH2D3A,CASP6,TOR3A,SRGN,DBF4,MFSD10,SAC3D1,CTNNBL1,YIF1B,CLDND1,TTC17,SLC25A1,GINS1,PAQR6,CSNK1G2,TELO2,ADAM17,HMGN1,NASP,ASPM,PPP1R21,PRKAR1B,SYMPK,TARS,SNRPA,MAPK3,HSPA1B,HLA-B,ATAD2,PLAA,ZNF330,OSBPL8,KBTBD7,PREPL |
| 2.761e-08 | -17.41 | REACTOME_M_G1_TRANSITION | MSigDB lists | REACTOME_M_G1_TRANSITION | 78 | 32 | 17377 | 2626 |
POLA2,MCM10,CDT1,DBF4,ORC1,PSMD9,RPA2,PSMD2,PSMD1,PSMA6,MCM5,ORC3,PRIM2,PSMA8,PSMB7,E2F3,PSMA1,CDC6,MCM2,PSMB9,PSMB3,PRIM1,RPA1,PSMC4,POLE,RPS27A,PSMD3,PSMD8,E2F1,E2F2,CDK2,PSMC1 |
| 2.776e-08 | -17.40 | DDOST (dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit) | protein interactions | 1650 | 88 | 36 | 17029 | 2761 |
COX15,SCAMP3,TMBIM4,SUZ12,COX4I1,FANCI,SSR1,GSTK1,RPN1,HUWE1,HADHB,RPN2,TECR,ATF2,POC5,SRSF11,STAU1,NXT1,TUFM,VDAC2,RFXANK,VDAC1,MCM2,KRTCAP2,DDX39A,DERL1,ATP1A1,MAGT1,SEC61A1,MAPK6,PGRMC1,ACADM,CLN3,EHD4,IGBP1,FAF1 |
| 2.799e-08 | -17.39 | GO_NEGATIVE_REGULATION_OF_GENE_EXPRESSION | MSigDB lists | GO_NEGATIVE_REGULATION_OF_GENE_EXPRESSION | 1432 | 290 | 17377 | 2626 |
ZNF496,MAX,H2AFZ,TXN,NUP188,KDM4A,TSC22D3,XIAP,CCNB1,UBE2I,RBM4,PARK7,CDK5,PA2G4,SRSF4,FNIP2,CRY2,NUP153,TIPARP,SMARCE1,DNMT1,SEH1L,SRSF10,PLK3,BAK1,KLF10,GABPA,AKT2,EHMT1,DDX20,AURKB,DOT1L,BRMS1,HHEX,SMAD2,RPS27A,RPS14,AXIN1,PRDX5,TFDP2,SMAD1,ARRB2,AAAS,PDCD4,HDAC2,POLR2K,EIF2AK4,PSEN1,METTL3,CDC73,CNOT3,TFAP4,CD59,KLF16,HDAC7,PHF14,DAPK1,TNRC18,PABPC1,NUP85,TERF2,ETV3,RBM42,FOXK1,MTA2,ZMYND11,BCLAF1,ARID1A,CBFA2T2,FXR1,MAP2K2,XRCC5,CAT,EPRS,PFDN5,POLR2J,ETS2,RBMX,CEBPG,PIAS2,CNOT6,YY1,RNF139,CDKN2A,EGLN1,ZNF296,DNMT3A,UBR2,SUZ12,MAGED1,WDTC1,RCOR3,PAIP2,SP100,NUP107,CDKN1B,RBM15,ATF2,CGGBP1,SAP30,CPNE1,POLR2L,EID1,ERF,DRAP1,CIRBP,POLR2D,RNPS1,CUL3,H2AFV,TRIM28,CHCHD3,ZNF282,DGCR8,HIPK2,STAT1,H2AFX,TRIM32,BEND3,LRP8,POU3F2,NCOR2,DEPDC1,MECP2,SRSF6,TCF3,FOXO3,HMG20A,MAD2L2,WWP2,PDCD10,ITGB8,SUV39H2,CREB1,CITED2,CNOT6L,NCOA2,TNFAIP3,ILF3,KCNQ1,ZP3,PICALM,POLR2A,CBX3,KEAP1,ZHX1,GPS2,PITX1,PML,HMGB2,DDX5,PARP10,IGBP1,PURA,CPEB2,RORB,TRIM11,SIRT2,SND1,BIRC2,PRNP,CREM,NUP210,CDC42,EIF4A3,GLIS2,JAZF1,METTL14,SIVA1,ZNF639,ETV6,NOC2L,SLC35C2,ARID4A,TRIM14,RYBP,PTPRK,SP3,PLK1,DEAF1,TRIM8,NCK1,PBXIP1,BAZ2A,VHL,EZR,BRCA1,PRKRA,PAF1,EIF4ENIF1,ZNF268,BEND6,RPS26,ZNF564,UBE2D3,PHB2,CENPF,NACA,TIA1,CTCF,MEF2A,SRRT,NUP205,RB1,NFATC3,MLX,MBD2,ZNF746,CTR9,TIMELESS,MDFIC,ZNF189,POLR2I,CIC,LDB1,EIF2AK1,RTF1,DAPK3,ZNF174,TSC1,SYNCRIP,NFIL3,NLRC5,NUP62,ZFP90,RBBP4,TOB1,N4BP2L2,USP7,MBD1,CYLD,MPHOSPH8,FOXM1,SMARCA4,IRF3,DUSP22,MXD1,SAP130,HNRNPA2B1,MDM2,TARDBP,STRAP,RLIM,MOSPD1,BIRC3,POLR2G,BTG2,PCGF6,ATXN1,NFATC2,NUP155,MBD3,RBL1,HNRNPR,STAT6,ARNTL,DNAJC17,H3F3A,SMAD4,CBX4,MIF,BCL2L12,UNK,DAP,RAE1,NUP54,ARID5A,NKRF,PAWR,MXD4,FZD6,BRD7,H2AFY,STAT3,RBM15B,TGFB1,ZNF202,BTAF1,PSPC1,RCOR1,PRMT2,MEN1,UPF1,BIRC5,GLG1,E2F1,RBPJ,NR2F2,HRAS,IFI16 |
| 2.843e-08 | -17.38 | U2-type spliceosomal complex | cellular component | GO:0005684 | 68 | 29 | 18223 | 2701 |
SART1,LIME1,CDC40,SNRPB,XAB2,SF3B1,SF3B6,PPIE,SMU1,CRNKL1,DHX8,PRPF3,SNRPD3,PRPF39,LUC7L,SF3A2,DHX15,PRPF18,SF3B2,LUC7L3,EFTUD2,BUD31,PRPF4,SNRPG,AQR,SNRNP70,LUC7L2,CDC5L,PRPF19 |
| 2.889e-08 | -17.36 | GO_ATPASE_ACTIVITY_COUPLED | MSigDB lists | GO_ATPASE_ACTIVITY_COUPLED | 300 | 82 | 17377 | 2626 |
DDX47,ABCA3,ABCC10,CHD1L,YTHDC2,TAP1,MYH9,DHX8,SMARCA4,ABCB10,ATP6V1B2,CHD1,ATP6V0B,ATP2A2,EIF4A3,XRCC2,ATP13A3,TAP2,TOP1MT,ABCC5,ATP6V1G1,RFC3,ATP13A1,SNRNP200,DDX20,ATP6V0A1,RFC2,DHX15,DHX57,RAD54B,DDX17,RAD51C,ATP1A1,RAD18,DHX16,CHD3,ATP6V0C,XRCC3,VPS4A,PSMC1,LONP2,ATP6V0E1,ABCA1,RAD51D,POLQ,DDX42,RECQL,CHTF18,DHX9,TOP2B,MYO9B,BLM,DDX56,ATP6V0A2,ANXA5,DDX31,ABCD1,GTF2H2,ATP6V0D1,ABCC1,DDX28,LONRF3,DDX24,HELB,DHX29,ATP2C1,DDX39A,CCT8,HSPA1B,XRCC5,DDX23,PSMC4,ATP6V1D,UPF1,KIF18A,NSF,ASNA1,DDX5,RUVBL2,ATP6V1C1,RBBP4,DDX52 |
| 2.927e-08 | -17.35 | HNRNPF (heterogeneous nuclear ribonucleoprotein F) | protein interactions | 3185 | 180 | 59 | 17029 | 2761 |
USP7,RAB14,CYLD,ZCCHC8,DHPS,IVNS1ABP,SUMO2,ACTR3,VAV2,DHX9,MOGS,DNAAF5,CUL1,PSMD9,RBM4,CDC73,WWP2,HNRNPA2B1,RPA2,RAB21,PDCD10,NOL11,EIF4A3,PPME1,ZNF746,TFG,HNRNPM,CDC5L,CDKN2AIP,STAU1,HARS,CUL3,BRCA1,EDF1,ADRB2,MCM2,TXNL4A,RHOT2,MATR3,DHX15,EIF3A,POLR2A,SRSF1,RPA1,CAND1,EIF4ENIF1,HNRNPR,ZNF689,RBMX,ACOX1,HNRNPH3,MAP4,DDX5,FUS,COPS6,CDK2,ARRB2,HNRNPDL,SMURF1 |
| 2.931e-08 | -17.35 | GO_RRNA_METABOLIC_PROCESS | MSigDB lists | GO_RRNA_METABOLIC_PROCESS | 238 | 69 | 17377 | 2626 |
SART1,DDX47,NOP2,RPLP2,EBNA1BP2,RPL11,RPL23A,KRR1,PA2G4,NOL11,EIF4A3,UTP18,EXOSC1,RPF2,FTSJ3,RPP25,RPL29,EXOSC6,RPL35,NOL8,RPL38,UTP3,GAR1,MAK16,RPS9,RPSA,RPL37,NSA2,LSM6,RPS27A,RPS14,TBL3,RPLP1,RNASEL,RRS1,FAU,PDCD11,RPS26,CSNK1D,RPS15,RPS2,RPL15,PNO1,RRP36,DDX56,EXOSC7,RPL17,RPL19,GEMIN4,FBL,ERI3,NSUN4,WDR18,TEX10,RPL8,UTP15,RPL6,RPS10,RPS24,BMS1,EXOSC9,RPL27A,TSR2,RPL36,UTP20,RPL32,CDKN2A,BYSL,DDX52 |
| 2.959e-08 | -17.34 | FERRANDO_T_ALL_WITH_MLL_ENL_FUSION_DN | MSigDB lists | FERRANDO_T_ALL_WITH_MLL_ENL_FUSION_DN | 82 | 33 | 17377 | 2626 |
POLA2,TXN,TRIP12,RRM1,SLC29A1,AP3S1,SDHA,APLP2,PCNA,PSMA6,GOT2,MCM5,DUT,EEF1D,MAPKAPK3,USP10,BCLAF1,PKMYT1,MCM2,DDX39A,CHAF1A,HMGN2,HINT1,COX8A,KHSRP,FKBP5,HMGB2,SRSF3,TFDP2,PGAM1,UBE2C,CDK2,TMEM131 |
| 2.962e-08 | -17.33 | protein polyubiquitination | biological process | GO:0000209 | 289 | 80 | 17256 | 2622 |
MIB2,UBE2E2,UBR2,CUL1,NHLRC3,BIRC2,ANKIB1,FBXO22,PSMA6,PSMD1,SIAH1,FBXW2,ANAPC7,TTC3,RNF19A,RNF26,RLIM,PRPF19,RBX1,PSMA8,CUL3,PSMB7,UBE2V1,TOPORS,BRCA1,CCNF,CDC23,CBFB,PSMB9,CDC16,RPS27A,PSMD8,PSMD3,TPP2,TRIM32,KLHL42,FBXL3,SMURF1,PSMC1,UBE2D3,TRIP12,ZFP91,SHPRH,UBE4A,PSMD9,WWP2,DTL,PSMD2,UBE2Q2,KLHL20,ZNRF2,HUWE1,FBXO7,PPIL2,BCL2,FBXL7,UBE3B,UBE3C,FBXL19,LRSAM1,RNF5,TNFAIP3,LONRF3,RFFL,PSMA1,FBXO9,ANAPC2,UBE4B,SYVN1,PSMB3,PSMC4,FBXO21,FBXO41,CDC27,SIAH2,UBE2C,RNF14,RNF139,ANAPC4,RNF114 |
| 2.977e-08 | -17.33 | midbody | cellular component | GO:0030496 | 168 | 53 | 18223 | 2701 |
EXOC3,CTDP1,KIF3B,PDCD6IP,PKP4,CYLD,URB2,CENPF,SLC2A1,CDCA8,KIF23,RACGAP1,SIRT2,SPAG5,ERH,PDXP,RAB8A,CLIC4,CDC42,ABRAXAS2,RALB,PIN1,KIF14,PRC1,DNM2,GNAI2,MICAL3,PLK1,PSRC1,RHOA,LAP3,TACC1,ASPM,LYRM1,JTB,TOPORS,AURKB,SEPT7,ANLN,SHCBP1,SH3GLB1,SEPT1,KEAP1,CHMP4A,BIRC5,ZNF330,CEP55,EXOC4,CCDC69,NUP62,CHMP4B,VPS4A,ANXA11 |
| 3.007e-08 | -17.32 | GSE12845_IGD_POS_BLOOD_VS_PRE_GC_TONSIL_BCELL_DN | MSigDB lists | GSE12845_IGD_POS_BLOOD_VS_PRE_GC_TONSIL_BCELL_DN | 192 | 59 | 17377 | 2626 |
FGFR1OP,MCM10,DEPDC1,FOXM1,MAGED1,PTTG1,KLHL18,KIF23,SMARCA4,RACGAP1,NANS,ORC1,CCNB1,NCAPG,BIRC2,FANCI,RNF103,SPAG5,SAC3D1,HNRNPA2B1,DTL,RFWD3,FANCL,TNS3,SLC1A4,BANF1,SEPT11,ALDH18A1,DNMT1,TACC3,TERF2,PPIF,ASPM,PBK,RAD51AP1,KIF15,MKI67,CDC6,AURKB,NFATC2IP,SMC2,SHCBP1,KIF11,SRSF1,HMGN2,MTHFD2,CSK,MFAP1,TFDP1,H2AFX,PKD2,ANP32E,ROCK1,EHD4,CCNB2,PGAM1,UBE2C,AP2S1,ESPL1 |
| 3.022e-08 | -17.31 | GSE27434_WT_VS_DNMT1_KO_TREG_UP | MSigDB lists | GSE27434_WT_VS_DNMT1_KO_TREG_UP | 183 | 57 | 17377 | 2626 |
PPIB,PRKCSH,DAP,DYNLL1,CDT1,MAN2B1,MXD4,PRKACA,REEP5,USP5,MBD4,BCAT2,TMEM179B,DAD1,SEC24C,RAB4A,ATP6V0A2,RPL19,SLC38A10,RNF26,CLN6,SLC35A1,LYPLA2,ABCC5,CDC37,SAP30,BAK1,CSNK1G2,SEC61B,GUK1,RBM42,SNRPB,PPP1R21,ZNF574,MFNG,UBE4B,OGDH,MBD3,SLC50A1,ECH1,AKAP1,YIF1A,ANKZF1,EIF3K,GNAS,SEC61A1,CSK,RBL1,PSMD3,FASTK,CDCA7L,STX18,CTSA,HRAS,ATP6V0E1,FAF1,PTOV1 |
| 3.022e-08 | -17.31 | GSE6674_UNSTIM_VS_ANTI_IGM_AND_CPG_STIM_BCELL_UP | MSigDB lists | GSE6674_UNSTIM_VS_ANTI_IGM_AND_CPG_STIM_BCELL_UP | 183 | 57 | 17377 | 2626 |
TMEM106C,RMND5A,MRPL9,NSMCE4A,CYLD,GOLPH3L,FAM53C,UROD,LETMD1,KIF2C,EZH1,IKBIP,RGS2,TWF2,MAP1LC3B,IFT27,TCF19,FOXO3,GIT2,CCDC28A,HLA-A,RNF103,JMY,PAIP2,CDKN2C,ADD3,ZNF260,TTC9C,KIF22,RNASEH2A,IMPA2,KDELR1,ADCY7,EID1,ATG9A,OXR1,HSDL1,GLO1,CCNF,SHCBP1,PDE3B,TTC33,BSDC1,GINS4,MASTL,GLOD4,NEK1,KIF18A,KIF18B,UEVLD,STK38,CDCA5,ZNF436,TFDP2,ZSWIM3,NGLY1,TOB1 |
| 3.022e-08 | -17.31 | GSE15330_LYMPHOID_MULTIPOTENT_VS_PRO_BCELL_DN | MSigDB lists | GSE15330_LYMPHOID_MULTIPOTENT_VS_PRO_BCELL_DN | 183 | 57 | 17377 | 2626 |
GOLPH3L,MRPL42,SYS1,RAF1,MRPS26,AGPAT3,CDC42SE2,CLCC1,EIF2AK4,CMTM6,EBP,APLP2,IRF4,CLIC4,TNFAIP8,CS,INTS12,ZBTB22,RNF19A,GM2A,CARM1,EIF5A,CYTH1,MND1,NRAS,DPM1,PGS1,OXR1,ATP2C1,PARP4,LDHA,JTB,TOR1AIP2,DCUN1D5,CYFIP2,OGFR,CAND1,ADSS,SH3BP5,KIF2A,DNAJC10,RAB18,AHNAK,TXNDC16,RBL1,SNAP29,MAFK,TPP2,TFDP1,CTBS,FTSJ1,NCOA1,BTF3,TMEM159,RNF14,GLCCI1,ALS2 |
| 3.022e-08 | -17.31 | GSE17721_0.5H_VS_8H_CPG_BMDC_UP | MSigDB lists | GSE17721_0.5H_VS_8H_CPG_BMDC_UP | 183 | 57 | 17377 | 2626 |
LZTR1,ADD1,NOP2,SUCLG1,CHERP,UCK2,TKT,ASAH1,HAUS4,MYO9B,RGS2,FOXO3,REEP5,SH3BP1,GOT2,ATG3,SIVA1,ADCY9,PELO,CS,ABCD1,CORO1A,CYB5R1,MAP3K14,TOP1MT,RNF26,TALDO1,SLC35C2,GNAI2,ATP6V0D1,PHKG2,NUP85,PABPC1,S100A6,TMED2,ALDH9A1,SRPK2,VOPP1,GALC,NSDHL,LDHA,MRPL16,NUTF2,ODC1,SNRPA,ANKRD46,RPA1,HAUS8,SDHB,CHCHD3,PFDN5,PDCD6,MYO18A,QRSL1,AP2S1,MYL12B,GPATCH4 |
| 3.081e-08 | -17.30 | CEP170 (centrosomal protein 170) | protein interactions | 9859 | 176 | 58 | 17029 | 2761 |
CEP170B,FGFR1OP,SKA3,MAPRE1,LUZP1,VAV2,AGO2,XIAP,CSNK2A1,KIF2C,AGFG1,CCNB1,CSNK1A1,HAUS2,SPAG5,CRKL,RFWD3,OIP5,CEP104,SMC3,SHC1,CENPJ,GTSE1,ARHGEF2,KIFAP3,MTPN,DCTN1,GPX4,SRPK2,CCDC138,NCK1,PSPC1,GOPC,PPP1R21,CAMSAP1,MTMR6,RRM2,MAP7D1,AURKB,RAB3IP,SMAP2,DAPK3,HSPA1B,NECAP2,HAUS8,KIF2A,UPF1,PCM1,CCDC6,ODF2,FAM83D,PKD2,WDR62,SASS6,ARRB2,YWHAH,IFI16,SNAPIN |
| 3.182e-08 | -17.26 | GSE7768_OVA_WITH_LPS_VS_OVA_WITH_MPL_IMMUNIZED_MOUSE_WHOLE_SPLEEN_6H_UP | MSigDB lists | GSE7768_OVA_WITH_LPS_VS_OVA_WITH_MPL_IMMUNIZED_MOUSE_WHOLE_SPLEEN_6H_UP | 161 | 52 | 17377 | 2626 |
CDS2,ADAM10,CHTF18,MRI1,GNE,TMX4,DBF4,PMS2,CDCA3,YTHDF3,NUF2,IKBIP,RMI1,CYHR1,SMC3,PPCDC,SOCS6,CENPM,RNF26,TPCN1,RNF169,CARS2,ELOVL5,TK1,CCDC138,MBLAC2,OXR1,LACTB,LRRC8A,DCTD,THNSL1,VDAC1,POLG2,TRIM28,PSMB3,ASF1B,NEU1,TMEM184C,ANKZF1,RAD51C,GPS2,STAT6,CDCA5,DTX4,MPV17,H2AFX,CHEK2,TFDP2,REEP4,SNX14,MYL12B,TIGD2 |
| 3.206e-08 | -17.26 | MRPL15 (mitochondrial ribosomal protein L15) | protein interactions | 29088 | 60 | 28 | 17029 | 2761 |
NOP9,COX15,RPS2,MRPL9,CYLD,MRPL42,MRPL39,MRPL12,RPL6,ILF3,MRPL16,OGDH,MRPL19,NDUFS4,RPL23A,CAND1,MRPL50,MRPL55,RPS14,DUSP11,CYC1,MRPL40,SNRNP70,MRPL11,MRPL13,MRPL3,MRPL32,MRPL57 |
| 3.223e-08 | -17.25 | REACTOME_SYNTHESIS_OF_DNA | MSigDB lists | REACTOME_SYNTHESIS_OF_DNA | 90 | 35 | 17377 | 2626 |
POLA2,CDT1,ORC1,PSMD9,RPA2,RB1,PSMD2,PCNA,PSMD1,PSMA6,CCNA2,MCM5,CDKN1B,ORC3,GINS1,RFC3,PRIM2,PSMA8,PSMB7,PSMA1,CDC6,MCM2,PSMB9,RFC2,GINS4,PSMB3,PRIM1,RPA1,PSMC4,POLE,RPS27A,PSMD3,PSMD8,CDK2,PSMC1 |
| 3.233e-08 | -17.25 | MUELLER_PLURINET | MSigDB lists | MUELLER_PLURINET | 291 | 80 | 17377 | 2626 |
BCCIP,HNRNPAB,WDYHV1,TPX2,ORC1,CCNB1,BRIX1,PRNP,PA2G4,PCNA,CCNA2,PSMA6,STRBP,GOT2,POP7,NOC2L,NUP153,BAK1,RFC3,AATF,KAT7,SNRPB,AURKB,MCM2,RFC2,POLG2,GAR1,TRIM28,FKBP3,CHAF1A,SRSF1,LSM6,LUC7L3,KPNA2,CHEK2,COPS6,COIL,SMNDC1,HDAC2,GEMIN7,POLQ,FUBP1,HSPH1,MCM10,EWSR1,CASP6,CDT1,FAM136A,PMF1,BLM,SPAG5,RPA2,VASP,EXOSC7,MBD2,ATIC,MCM5,MSH2,ANP32A,GEMIN6,BCL2,FBL,GTF2H2,MSH6,PPAN,PHF10,TK1,MYBL2,EXOSC9,SNRPA,RPA1,XRCC5,SLC19A1,SYNCRIP,BIRC5,PIAS2,TCOF1,SRSF3,CCNB2,BYSL |
| 3.233e-08 | -17.25 | GO_ORGANELLE_SUBCOMPARTMENT | MSigDB lists | GO_ORGANELLE_SUBCOMPARTMENT | 291 | 80 | 17377 | 2626 |
RAB14,CORO7,SYS1,TRIP10,ADAM10,RAC1,VTI1A,TGOLN2,AP1B1,BECN1,APP,BCAP31,RAB21,ASAP2,AP1M1,DNM2,NSFL1C,ZFYVE27,AP2B1,CLTB,PLK3,USO1,TMEM115,RHOBTB3,ATG9A,NCK1,APH1A,LAP3,AP4E1,STX16,OPTN,GOLGA8A,MYO18A,CANT1,AP1S1,ST3GAL2,B4GALT3,CLN3,CHPF2,CHID1,B4GALT2,GOLIM4,GOLPH3L,SCOC,TMBIM4,B4GALT5,B4GALT1,ARFIP2,RAB6A,ARF1,TMED3,B4GALT4,GGA2,TMEM165,RAB11A,HLA-A,FKBP1A,KLHL20,FUT8,TMED2,B3GALT6,NAGPA,MOB4,GCC2,TRAPPC9,ATP2C1,COG1,GOSR1,GNAS,NUCB1,RAB18,GALNT2,GOLGA4,GOLGA2,GOLGA7,NSF,OSBPL8,ARAP1,VCPIP1,SMPD4 |
| 3.253e-08 | -17.24 | GSE6269_FLU_VS_E_COLI_INF_PBMC_UP | MSigDB lists | GSE6269_FLU_VS_E_COLI_INF_PBMC_UP | 148 | 49 | 17377 | 2626 |
PARP12,AGRN,DCAF15,CXXC1,MOGS,STRN4,DLGAP4,SLC4A2,IRF3,MYO9B,HLA-A,CNOT3,RFWD3,SHC1,ATP2A2,PPIG,DNM2,RPN2,PDIA6,GNAI2,TRIM14,KDELR1,DCTN1,EBAG9,TGFB1,ATP13A1,MLEC,WIPF1,USP10,EMP3,OGDH,NFATC2IP,ARPC1A,MARK2,PDHX,ISG15,HLA-B,NUCB1,WAS,GOLGA2,BRD2,CDC27,PROSER1,NUP62,ACTB,USP11,PURA,NRBP1,IFI16 |
| 3.254e-08 | -17.24 | env (gp160; envelope glycoprotein) | protein interactions | 155971 | 1501 | 320 | 17029 | 2761 |
RAB14,PDCD6IP,MAX,TXN,GXYLT1,ADAM10,PRKCSH,AP3M2,IKBIP,OAT,CCNB1,UBE2I,PABPC4,CALM2,PSMD1,SRSF4,AP1M1,DNM2,AP2B1,TRA2B,LRRC59,TIPARP,SEH1L,SRSF10,CDC5L,SRP72,NRAS,KLF10,AKT2,HNRNPF,MCL1,SLC25A5,ARF4,EIF3A,STOML2,WAS,SMAD2,TMED10,LIMK1,MYO18A,ITGB1,COX5A,ST3GAL2,CHPF2,TRAF5,B4GALT2,PPIB,HSPH1,POLR2K,HLA-E,RHOC,VAV2,DHX9,B4GALT1,CYCS,MAN2B1,ITGB5,COPB2,SPAG5,CFLAR,CD59,FKBP1A,RPN1,TPST1,GNAI2,PABPC1,LUC7L2,EEF1D,TIMM8B,MAN1B1,ERO1A,FAM133B,SRSF5,TOMM40,PKM,MAP2K2,MATR3,CCT8,FAS,SEC31A,CAT,EPRS,POLR2J,TTC13,NSF,CSK,RBMX,ERGIC3,ACLY,PPP3R1,SMPD4,GPI,MAP3K5,CDKN2A,REPS2,NQO1,RAF1,SF3B1,EIF3D,ACTR3,RAC1,VTI1A,MYH9,BCL2L1,AP1B1,PRKACA,CPNE3,APP,ABHD16A,SP100,ATP2A2,ADCY9,CDKN1B,TAP2,ATF2,CLN6,CFL1,ADCY7,CCT2,POLR2L,IDH3A,VDAC2,POLR2D,RAB1A,TRIM28,DDX17,CHMP4A,HSPA4,SEC61A1,DDOST,HINT1,JAK1,SAFB,STAT1,SEL1L,B4GALT3,TUBB,RPS2,MANBA,FLOT1,SDF2L1,BLM,RAB11A,HLA-A,GTF2F1,CAPN2,PSMD2,PTEN,RPL17,ARF5,FUT8,ARHGEF1,PTPN11,ANXA5,RPL19,TAGLN2,NAP1L4,CREB1,HNRNPM,TMX1,SPTAN1,LDHB,STAU1,PPP3CA,LDHA,RPL8,ILF3,ECH1,PRDX1,FADD,POLR2A,PLD3,MAGT1,PRDX3,HNRNPH3,MAPK6,LRPPRC,PML,KHSRP,LY75,DDX5,CD81,HNRNPAB,COPA,KMT2E,MOGS,CDIPT,MAPK14,BECN1,MAP1LC3B,BIRC2,KRR1,SF3B2,RAB8A,NUP210,CDC42,EIF4A3,AP3S2,SIVA1,PIK3R2,LARS,SNRNP200,PBXIP1,EZR,SUMF2,DHX15,CHAF1A,MAN2A2,TIMM13,ACTB,ROCK1,CHEK2,NGLY1,CAPN1,FUBP1,PHB2,NACA,SDC2,PCSK7,EPN1,COX4I1,CDK13,PPP3CB,NCKAP1,RAB6A,B4GALT4,APOPT1,RB1,NFATC3,YBX1,BCL2,ALDH18A1,ATP6V0D1,ABCC1,POLR2I,ACSL3,RPL6,PSMA1,KRAS,GOLGA4,SYNCRIP,SIL1,RUVBL2,ATP5F1A,PTDSS1,WASF2,GLT8D1,SART1,TOMM20,TMX4,IRF3,PCBP1,LYN,BCAP31,VAV1,HNRNPA2B1,TNFAIP8,IARS,SAR1A,TARDBP,CLTB,LMAN1,PDIA6,F2R,RPL29,BIRC3,POLR2G,BTG2,RAB7A,NLN,TOR1AIP2,NFATC2,NUP155,VDAC1,NDUFB1,TOLLIP,RPS9,SRSF1,DNAJC10,PON2,ATP1A1,SURF4,TAB2,HNRNPR,AP1S1,MAPK1,AP2S1,CHID1,CASP6,TOR3A,TMX3,NKRF,AP3S1,PIP4K2A,TFRC,RGS1,MAN1A1,CTSS,TTC17,STAT3,RNF5,TGFB1,ADAM17,RHOA,PRKDC,TUFM,NEU1,ZFR,HSPA1B,MAPK3,DDX23,CTSL,HLA-B,UPF1,OSBPL8,PGRMC1,GLG1,E2F1,SPCS3,HRAS |
| 3.274e-08 | -17.23 | cadherin binding | molecular function | GO:0045296 | 325 | 88 | 17224 | 2647 |
EXOC3,WASF2,ADD1,RAB11B,CAST,ANK3,OLA1,MYH9,SND1,PCBP1,TWF2,KTN1,PARK7,RPL23A,CRKL,PPME1,EIF5,LRRC59,ABI1,RPL29,USO1,SEPT9,NCK1,EZR,ANLN,CHMP2B,RAB1A,ERC1,GLOD4,AFDN,AHNAK,STK38,SH3GLB2,STAT1,ITGB1,ATXN2L,CHMP4B,RPS26,NUMB,PFKP,CSNK1D,RPS2,MAPRE1,SCYL1,RPL15,ARFIP2,ARGLU1,DNAJB1,PSEN1,PDXDC1,BZW2,KIF5B,VASP,ATIC,AHSA1,CAPZA1,CNN2,TAGLN2,EEF1D,LYPLA2,NUDC,SPTAN1,SNX2,DHX29,RPL6,LDHA,RANGAP1,PLEC,EIF2A,PKM,SEPT7,EIF4G2,MACF1,EIF4H,MARK2,CCT8,PICALM,PRDX1,CIP2A,SH3GLB1,PDLIM1,GOLGA2,YWHAZ,EHD4,CCNB2,PDLIM5,ZC3HAV1,ESYT2 |
| 3.295e-08 | -17.23 | glioma | COSMIC cancer mutations | glioma | 16557 | 2515 | 17385 | 2587 |
HECA,ZBTB10,ABCC10,HEXB,CCNL2,FBXO22,EEF2K,THAP4,RAD23B,ATP13A3,DNM2,ZNRD1,FTSJ3,USP34,CCDC57,ERCC1,NRAS,EHMT1,KIF15,HNRNPF,WDHD1,MIER2,DIDO1,MCM2,RAB22A,SMAD2,MID1IP1,RPS27A,MYO18A,OGT,MPV17,COX5A,SMAD1,ZNF75A,ANXA11,SLC25A33,SEC61G,GGA1,MUM1,CCZ1,TRIO,CUTA,RAB23,KCTD17,HAUS4,EIF2AK4,APH1B,PARN,CDC73,MYL6B,ATG4A,TMEM179B,PDXP,SMC3,GEMIN4,MVP,NUP85,PPP6R1,PABPC1,NSUN4,PPA1,IFRD1,AGGF1,FOXK1,RBM42,GTPBP4,MAP7D1,MRPL16,ELK1,EIF4H,RDH11,MAGED2,KPNA1,ETS2,TYW5,WIPI2,RUFY3,PDLIM5,ACSF2,RHOG,EXOC3,STARD7,VTI1A,C5orf30,INO80E,SLC35B2,LCLAT1,RCOR3,CPNE3,KIAA1147,RBM23,ZNF420,AHCTF1,TBC1D22A,TBC1D14,GMEB1,NSFL1C,SEPT11,GPD1L,ZC3H3,ARL5A,PDCL3,SNX8,ERMP1,EID1,IDH3A,POLR2D,HTATIP2,MEF2D,TMEM147,GSTCD,TANC1,MAT2A,VPS26B,NSMCE2,CORO1C,CAMKMT,PPP5C,PITRM1,TUBB,COMMD10,ZNF445,SRSF6,HABP4,CCM2,FLOT1,BTN3A1,ATG2B,ABHD14B,PPP1R3B,ZBTB45,HUWE1,ZNF260,NAA50,ANXA5,LTN1,UBE3B,NAP1L4,ZNF710,ST8SIA2,RPL22L1,MED22,SPTAN1,STAU1,DDX24,TCTEX1D2,TACC1,MRS2,LDHA,HEBP2,LLPH,RAB3IP,TTC33,PICALM,SH3BP5,SLC19A1,ACOX1,FAM3C,AEN,PARP10,YWHAH,THAP5,GPATCH4,FAM129A,TRIM11,YTHDC2,SNX15,RBM8A,ENSA,NENF,SND1,RUFY1,TRIM65,ZER1,PRNP,KRR1,RAB8A,NUP210,NT5DC1,NOC2L,EIF5,TACC3,RYBP,VPS13B,PTPN18,MIOS,SNRPB,MBLAC2,CDC6,UTP3,PBRM1,ODC1,USP21,TRAM2,FBXO28,BCL7C,ARRDC1,ADAM9,DVL1,NUMB,ZNF564,FUBP1,C1orf74,CTU2,PARP12,ZCCHC9,CENPF,LAMTOR3,CHCHD2,NCKAP1,LYRM2,RSAD1,TNS3,SUB1,RINL,SSBP3,KIF13B,MBD2,XPA,AHCY,RBM3,GLE1,LRSAM1,HDHD2,NTPCR,NSDHL,AMD1,CAMSAP1,ZNF761,METTL22,ICAM2,STYXL1,APPL1,BBS12,ANKRD46,RXRB,SDHB,PCM1,GALNT2,TMEM168,NLRC5,RUVBL2,BTBD10,MYO9A,CCNB2,USP7,GLT8D1,RPLP2,SUCLG1,ARID2,TMX4,SLC2A1,ATP6V1B2,PCBP1,LYN,BCAP31,VAV1,TMEM69,MRPL50,PSMA6,ZNF473,ZNF302,BRPF3,TARDBP,BCAP29,CTDSP2,PRPF19,PPIF,KDM3B,MND1,CLCN3,BIRC3,RAB7A,ANKRD33B,PPIE,CHMP2B,VDAC1,EIF3H,TMEM201,GLOD4,IDE,DHX16,UHRF2,CHMP4B,XRCC3,PARD3,BCL2L12,C19orf53,MCM10,KLHL21,PDAP1,CDCA8,TMX3,ARF1,SLC12A9,TUBGCP2,DNAJB9,HOMER1,POLR1B,RNF5,RBM15B,PPAN,RHOA,RPRD1A,BTAF1,TOP3A,ARHGEF12,PCGF1,DDX23,RAB18,CACNB1,TRIM26,PDCD6,ATP6V1D,L3MBTL3,FAM110A,NEIL3,CTBS,BBX,IMPDH1,TAF12,NR2F2,PGAM1,HIPK3,IFI16,TXN,NUP188,H2AFZ,PNISR,PRKCSH,USP39,UBE2I,PARK7,SLC25A37,ASPHD2,ZNF428,RAB4A,TRA2B,SUCLG2,TAF5L,SMARCE1,ZNF800,CDC5L,ZNF524,SGCE,OSBP2,NSUN2,USP22,CLNS1A,EIF3A,ZMYM3,DOT1L,IWS1,ANKRD10,WAS,KIF18B,TPP2,C1orf109,ZMAT3,B4GALT2,PRPF38B,RECQL,C9orf78,EWSR1,GADD45G,RRM1,ACAP1,B4GALT1,CYCS,FAM136A,SUPT7L,TMEM165,CNOT3,NPLOC4,WDR48,SPAG5,RTKN,CEP104,EXOSC7,KLHL5,LRRC8D,PPP4R1,MSH2,PIGG,OSTF1,FBXL7,MRPL40,TNRC18,SYTL3,FAM171A1,APOL1,EIF5A,GCC2,PRIM2,ELL2,RDH10,MFNG,RPS24,GORASP2,CAPZA2,ADRB2,CCT8,MTR,PHF6,PFDN5,SLCO4A1,TTC13,GOLGA2,RBMX,MED15,PIAS2,APPL2,SAMD8,CDKN2A,NUDT3,ZNF511,ATXN3,RAF1,KIAA0232,C2orf49,EPM2A,CD320,CCNA2,MTMR4,BRI3,TP53BP2,AQR,RBM12B,ILKAP,CDK12,SAP30,BRD4,DRAP1,NARF,LRRC8A,ELP4,ABHD11,PKMYT1,ASB13,SERP1,TRIM28,SUPT16H,EIF3K,CHMP4A,ATF6,XRCC4,ADAM23,PRPF4B,NDUFS1,DEPDC1,MECP2,SECISBP2,HMG20A,WWP2,SLC25A36,JAKMIP1,CCNK,DNAJC8,AXIN2,CITED2,JMJD4,ANKRD37,KAT2A,TMEM126B,RABIF,ADSL,PACS1,BMS1,KCNQ1,ARSK,MACF1,KIF11,COMMD4,KLF6,SMAP2,FADD,SH3GLB1,MYO1F,CBX3,TMEM127,INF2,PPP1R11,DUSP11,DDX5,WDR62,TAF6,ESPL1,PURA,DDB1,DEF6,FAM83G,IPO4,UBL3,NAT9,PIGM,LYRM4,GPR132,UBE2Q1,PTP4A3,BRIX1,MRPL19,ZNF696,SF3B2,PCYOX1L,CDC42,SYNM,GOT2,JAZF1,HADHB,RPF2,SLC35C2,CNNM3,CARM1,SRPK2,WDR41,LARS,ZCCHC10,CCDC138,LRBA,TMEM216,SUMF2,KMT2C,OGFR,PRPSAP1,ASF1B,RPL37,MAN2A2,EIF4ENIF1,NIP7,U2SURP,MIA2,ZNF268,ATP6V0E1,PPP1R2,PM20D2,XPNPEP3,RGS2,LYAR,FAM89B,POLR2I,TRAFD1,SUGP2,GBA,SYVN1,DAPK3,ARHGAP15,MASTL,UAP1,NFIL3,FN3KRP,YWHAZ,CTSA,TMEM14A,TOB1,TSEN15,ADNP2,TCF12,PRKAB1,MDH2,SMARCA4,ORC1,RRN3,UBXN2A,IARS,CD3EAP,KIF14,EXOSC1,CS,CLTB,DNAL4,CSTF1,POU2AF1,UBQLN4,NXT1,HPDL,PGGT1B,SELPLG,SMU1,ATXN1,GLO1,OGDH,BICD2,CADM1,EDEM2,HERPUD2,TOLLIP,FANCE,MBD3,PDHX,RPS9,ALKBH6,SURF4,DUS3L,ARNTL,ANP32E,FKBP5,TMEM101,CCDC125,ABCA1,PDCD2L,GCLM,RAE1,DCTN2,NUP54,CHIC2,PAWR,MXD4,DCUN1D4,PIP4K2A,XPR1,FERMT3,KIF5B,KLHL20,SEC24C,RRBP1,ARHGEF2,ANP32A,LDLRAD3,STAT3,MYO5A,NIPAL3,AMPD2,TXNL1,PHF20L1,DCAF6,FAM49B,TMEM39A,ATP2C1,RFFL,COG1,RCOR1,PRMT2,TFEB,LEMD2,UPF1,ELMO1,ZC3H7B,DTX4,ZMIZ1,TERF1,HRAS,CCDC93,FGFR1OP,TMED7,PIGQ,AGPAT1,CNTROB,PPP1R16B,MIS12,GSDMB,TTC9C,PDS5B,NUP153,SENP1,PGAP2,TMEM115,PLEKHM3,DCUN1D5,PLEKHF2,BRMS1,PWWP2B,TRIM47,WDR11,AXIN1,SMG9,TRIM52,LONP2,NDUFV2,PHF23,CERK,SLC4A2,EZH1,ITGB5,LMNA,MCTS1,DDX56,EIF2S2,SLC38A5,FOXN2,CARS2,PRRC2A,C16orf72,RB1CC1,ZMYND11,PGS1,MYBL2,UHRF1BP1,SRSF5,MPG,MATR3,CYB5A,NCDN,POLR2J,SETD3,TEX30,PTAR1,CNOT6,NDE1,EGLN1,ZNF207,ANKRD27,PPP1R37,ABCA3,IVNS1ABP,MON1B,RMI2,TMEM97,NIT2,NUF2,ZNF267,TCF19,TMEM161B,KTN1,APP,PRKD3,CLUAP1,ATP2A2,UTP18,GRSF1,DUT,ZCCHC2,ANAPC7,RNF19A,FAM76B,CLN6,TMEM9,GCC1,RNF169,ADCY7,ATP6V1G1,ENPP4,RNPS1,CDCA2,FKBP3,GPR137,DDX17,CHCHD3,PEX5,CDC16,HIPK2,MBOAT1,TICAM1,PDXK,ZBTB11,ANXA6,TMBIM4,GMCL1,UBE4A,IL21R,ETS1,WRB,ZNF92,PNO1,CAPN2,ADD3,SUV39H2,TTLL12,TPCN1,TMX1,LYPLA2,HNRNPM,MFSD12,LDHB,PPP3CA,NUDT8,POLK,JTB,EMP3,MTMR12,ZP3,PDE3B,KIF18A,CCDC6,WNT5B,MAPK6,C4orf46,LY75,SLC25A19,RGL1,PSAP,WDR76,IGBP1,FAF1,SNAPIN,COX15,THOC1,AGRN,GNPDA1,GPBP1L1,PPP1R15B,CSNK2A1,EBNA1BP2,GIT2,BIRC2,ATPAF1,DLG5,ABL2,XRCC2,ZFYVE27,MCMBP,PTPRK,CDC37,METTL1,SP3,EXOSC6,HARS,GMFB,ESYT1,ANLN,RAB5B,RHEB,DPYSL3,TBC1D17,TIMM13,CDCA4,TONSL,NRM,NAGLU,ACTB,ZNF45,TMUB1,CTCF,ASAH1,DOCK11,CRLF3,ASXL2,LRRC14,NUS1,SLC27A4,AFF1,MDFIC,MAML1,CYTH1,NQO2,UTP15,EIF2AK1,EIF4G2,ZDHHC3,MOSPD3,ITPRIPL1,CDC27,SNAP23,TBPL1,PRMT7,KCTD7,NDUFA5,CYLD,UGP2,DYNLL1,COPE,HCFC1R1,ZADH2,GGPS1,RPAIN,RAD23A,ATP6V0B,PDK2,STRBP,DUS4L,MRPL34,PDCD2,SAP30L,CLPTM1,SLC39A9,RPL29,RPL35,BTG2,DNAJC9,FRAT2,MTMR6,NFATC2,KDM1B,ARL5B,USP36,CCDC127,MRPL2,ATP1A1,CLK3,MAFK,PSMD3,NDUFA11,CEP55,ZNF436,DNAJC17,NCOA1,SLC25A39,ZC3HC1,ZNF146,ATXN7L2,CDC40,SMAP1,GOLIM4,RRP15,DAP,GNE,SMC6,ARFIP2,NKRF,CHAC2,BZW2,WRNIP1,SS18L1,CENPM,PTGES3,CAMK2G,MLEC,ZNF202,PPWD1,FAM50B,RHOT2,NEU1,TPD52L2,GOLGA7,TWSG1,GLG1,PGRMC1,FAM126A,RPS6KC1,UBE2C,PPCS,NDUFB6,TMEM41B,ZDHHC8,PLXNA1,CCNB1,SLC20A1,COMMD6,ABHD14A,POLR3K,C14orf119,ASAP2,SNUPN,CNPY4,PLCL2,TFG,SEH1L,ATG9A,PBK,MKI67,DDX20,AMDHD2,GALNT7,SLC17A5,CCNF,FOXRED1,RBM47,PTER,WDR4,DHTKD1,TRAF5,HDAC2,PWWP2A,HSPH1,MAPRE1,CHTF18,ADO,KIF23,SLC35B1,NOTCH2,JMY,NDUFAF6,FKBP1A,SLC31A1,SNX18,ATIC,ATP6V0A2,PIKFYVE,RNF135,LPCAT1,EEF1D,TMED2,PHF10,FTL,DDX28,ZNF84,SIGMAR1,PIP4K2C,RIT1,PLEC,KDM3A,SF3A2,FAS,EPRS,ZNF777,TMEM54,QARS,PPP3R1,TCOF1,NRBP1,CABLES1,DNMT3A,RWDD1,CKLF,TRIP10,SF3B1,RPS6KA1,SUZ12,CAST,RAC1,GPR89A,OLA1,SNN,GNB2,FLAD1,APLP2,KDM2A,TNPO2,CDKN1B,TALDO1,GPX4,ATP13A1,RFC3,MAPRE2,ERF,CUL3,SLBP,KIAA1586,H2AFV,POLG2,GAR1,PSMB9,DHX57,NSA2,HSPA4,MRPL55,JAK1,TBL3,SEL1L,H2AFX,KLHDC4,B4GALT3,PDCD11,ATMIN,POLQ,POU3F2,OTUD5,NCOR2,ANKRD13D,PKP4,SCAMP3,BABAM1,CDCA3,SLC25A12,BLM,TMCC3,GTF2F1,RPL17,CRAT,AHSA1,PRC1,UPF2,COPS7B,SLC38A10,CNOT6L,CNPY3,UBE2M,IFT46,TMEM160,TSHZ1,ZFP64,DENND4C,DENND1B,WDR18,RPL8,ILF3,LRRC1,RHOT1,TSR2,MARK2,ECH1,PRDX1,PLD3,NUCB1,GNA12,FBXO21,C1orf131,PRDX3,PFDN4,HNRNPH3,STX18,TFDP1,KHSRP,ASNA1,CPEB2,SSSCA1,BYSL,VPS29,S100PBP,MIB2,IER2,PTMS,NOP2,UBN1,DCAF15,NF1,ALKBH5,MOGS,UBE2Z,TAF6L,MAPK14,BECN1,SNAPC4,RNF103,BCAT2,MBD4,C18orf32,METTL14,IMPAD1,ZNHIT6,RCSD1,PHTF1,SRI,KIF22,ZBTB22,NFU1,OGG1,TRIM14,ELOF1,COPS8,FYTTD1,TRIM8,RRM2,SOX4,ABHD5,UBTF,CXXC4,PAF1,UEVLD,SPATA2,PQBP1,IARS2,ATXN2L,GALNT10,STARD3NL,RPS15,PIGN,AGTRAP,CIB1,XPO7,SRRT,ZNF449,CAPZA1,GLTP,BCL2,KIFAP3,N4BP2,HP1BP3,VOPP1,THNSL1,ISG15,CAND1,GNAS,TSC1,RBM25,CDCA5,ZFP90,NANP,RBBP4,ZBTB24,SMARCD1,MBD1,WASF2,MMACHC,TOMM20,IFI27L1,GNPNAT1,MPHOSPH8,HNRNPUL2,CHD1,MEAF6,C2orf68,CCDC50,AKAP8,PARL,RPN2,CHTOP,FAM3A,F2R,TMEM14C,SCYL3,ABI1,HTRA2,MOSPD1,RLIM,FAM172A,ZNF500,PSMB7,NLN,WIPF1,BOLA1,BUD13,NDUFB1,PEF1,EIF3G,BTBD1,TAB2,CHCHD1,TULP3,WDR59,CANT1,SCARB1,GAS2,USP11,SMURF1,PPP2R2D,TSPAN5,CDS2,MAGEH1,MRPL42,EYA1,CDK2AP2,MRPS26,LETMD1,KLF13,HDDC2,RGS1,MAN1A1,FBXO5,GART,TANK,BRD7,MRPL11,SAMD4B,ZDHHC18,GTF3C6,POLR3GL,WDR81,MEN1,ZNF407,MFN2,COX8A,ZRANB2,SRSF3,MBD6,ATP6V1C1,IDH3B,TATDN1,TSC2,LACTB2,CMTM6,RBM4,ZNF275,RPL23A,CDKN2C,NAPG,USF1,MECR,AP1M1,UPRT,CRY2,ECD,RNF26,TIPARP,LRRC59,ANKRD9,RHBDD2,MGAT5,BAK1,ZNF559,RHOBTB3,GABPA,WBP1,NUTF2,ARF4,GINS4,KRIT1,BOLA3,AHNAK,RAD18,PDRG1,RNASEL,CHPF2,OAZ1,PDCD4,SMNDC1,NXT2,HIVEP3,KIAA0100,CLSPN,RHOC,DHX9,PDCD7,PSMD9,HAUS2,COPB2,TFAP4,CD59,RNFT1,RIMS3,MEGF8,EFTUD2,FBXO7,CPSF4,MRPL21,PHKG2,LUC7L2,SRSF11,EIF3L,MTA2,TYW1,USP10,ITM2A,SSR2,BCLAF1,MTX1,SFXN5,FNTA,PDLIM1,TXNDC16,TMEM159,MRPL3,ALS2,FAM72A,TRIM41,KARS,NQO1,POC1A,ANK3,PTTG1,TPX2,TBC1D13,DAZAP2,STMN1,GLRX3,C19orf48,REPS1,ABHD16A,FBXL6,SH3BP1,MTA1,UBA5,CLCN6,INTS12,C8orf59,RPRD1B,CGGBP1,CPNE1,SEC61B,POLR2L,FAM118B,GOPC,E2F3,CIRBP,RPL38,CRNKL1,PFKFB3,GORAB,RAB1A,GIGYF1,TMEM184C,PPP2CA,KIF2A,CCDC14,LSM6,RNF38,SNRPG,DMWD,USP13,ZFP91,TRMT6,IP6K2,WDR5,SLC25A43,PMVK,IFT27,NEIL2,RRP36,SRXN1,RPA2,PSMD2,CLIC4,PDCD10,CBWD2,COQ4,ITGB8,ARF5,ARHGEF1,FBXL19,GTF2H2,TTPAL,UTP20,MAGT1,GPS2,DBI,SSNA1,MRFAP1L1,CD81,TMEM131,WDR13,FANCI,PAPOLA,CREM,FANCL,TET3,GLIS2,IL6ST,INTS1,POP7,SLC44A1,MTPN,ASB6,PLK1,RPP25,CELSR2,SEPT9,RBX1,APH1A,RAD51AP1,CKAP2L,PSMG1,UBE2V1,EAF2,IL12RB1,KRTCAP2,LUC7L,LSG1,NECAP2,C1orf122,TRIM4,ALG3,AGPAT2,CHD3,ZNF367,E2F4,PRPF4,KPNA2,BEND6,CLN3,DNAJC30,FAM208A,NGLY1,POT1,MYL12B,CCDC137,RMND5A,HJURP,PHB2,FAM53C,DNAJB2,NKD2,SDC2,KLC1,CDK13,ADCK5,COX4I1,RAB6A,DNAJB1,ARID1B,C1GALT1,MLX,UBE2Q2,CCP110,ZNF746,ARL6IP1,CTR9,NIPSNAP1,ABHD2,DCAF8,ACSL3,LDB1,MAP4K3,ARMC8,RBM38,IRF5,NMT2,RPL36,HAUS8,MBIP,ORMDL2,COX7A2L,ZDHHC7,FAM122A,SIL1,DTD1,UNC13C,BCCIP,SART1,TRAF7,NDUFAF2,TOR1AIP1,ZNF416,LAGE3,TM9SF3,ZFYVE21,RRAGC,ZNF121,OIP5,NRF1,WDR44,PIN1,PPME1,EFCAB11,RPAP1,CABLES2,TOP1MT,LMAN1,AHCYL1,STRAP,SPSB3,ZNF583,SNX25,ARHGAP17,POLR2G,ZNF780B,PPT1,NUP155,DCLRE1C,MRPS14,RHBDF2,SUGP1,RBL1,FASTK,UBXN2B,STK38,AP1S1,SPRYD4,SLC22A23,H3F3A,CHID1,SMAD4,RAD51D,SLC30A9,NADSYN1,UNK,CMAS,HMGN3,NCAPG,SCYL2,FZD6,HERC3,GTPBP3,CTSS,ORC3,RNLS,YTHDC1,ACP2,CSRP1,HMGN5,METTL5,ABCF2,TUFM,RANGAP1,PNPLA8,HAGH,API5,ZFR,SEC23IP,E2F1,USP20,TMEM219,RBPJ,MAX,PDCD6IP,LUZP1,GXYLT1,ADAM10,CXXC1,TSC22D3,AP3M2,CUL1,GYG1,NANS,OAT,MYEF2,ANKRD26,PA2G4,NOL11,FIZ1,ZNF200,MARCH2,SLC26A2,SRP72,KLF10,LACTB,RFC2,CBFB,RAB2B,PRIM1,MAP3K4,HHEX,RPS14,LUC7L3,MAP4,MRPL27,BTF3,PTPDC1,CCDC59,NMD3,PTOV1,COX5B,DNAJC5,SCOC,DHPS,POLR2K,ANKH,PRKAA1,VAV2,C16orf87,GSPT2,DLGAP4,PXMP2,PRPF39,PSEN1,ZNF79,PDXDC1,VPS25,NDUFS7,YY1AP1,C12orf10,FAM192A,RPN1,LHX8,ARPC5,ZNRF2,DAPK1,TPST1,PIK3IP1,CYC1,SOCS5,FDFT1,PIGT,WDR1,EMB,ZNF574,C1orf35,EXOSC9,ARID1A,PTTG1IP,C9orf40,FXR1,GOSR1,MAP2K2,TWISTNB,AKAP1,XRCC5,HMGN2,PI4K2A,CAT,SEC31A,DERL1,MTHFD2,HSPBP1,CEBPG,ARAP1,FAM83D,USP32,CABIN1,SMPD4,GPI,CYTIP,TP53RK,REPS2,RAB11B,UROD,SLC39A13,POMP,BCL2L1,NUDT19,DECR1,RALB,SIAH1,LPIN2,ADCY9,SOCS6,MRPS27,TTC3,RNASEH2A,CFL1,ANKLE2,CDC123,OAF,VDAC2,EDF1,ERC1,EML4,AMZ2,ANKZF1,ZNF282,RAD51C,DSN1,DDOST,HINT1,DGCR8,SAFB,HAGHL,LMBR1,FTSJ1,RWDD4,NCLN,BEND3,EYA2,DYNC1LI2,SLC41A1,B4GALT5,MANBA,TKT,FAM76A,CBLL1,ARGLU1,LANCL1,POFUT1,FAM8A1,HEATR5B,HLA-A,EBP,RFWD3,NDUFA2,FUT8,BTF3L4,PTPN11,MRPL54,FEM1B,RPL19,CNN2,NDUFA3,MTX2,MSH6,PDLIM2,LONRF3,RFXANK,FBXO9,GUF1,RPL32,ZHX1,NDUFS5,WDR91,GPR89B,HIGD2A,ZBED3,RORB,POLA2,ZNF76,MTX3,COPA,HMGXB3,PHRF1,ABCB10,COMMD5,MAP1LC3B,DST,SIVA1,RAB35,GPATCH1,TCEA1,DRAM2,DEAF1,SNRNP200,NCK1,LAP3,VHL,SREK1,ARHGDIB,PITPNB,HSPB11,BRWD1,PPM1G,SH3GLB2,CRCP,BAZ1B,ACBD4,CAB39,STK11,CLU,CHEK2,ZSWIM3,TSTD2,CHPT1,MRPL13,DCAF5,CAPN1,UBE2D3,NSMCE4A,PPP1R12A,ZCCHC8,GORASP1,UBXN1,NACA,PCSK7,RPL15,THRAP3,TTF1,QSOX2,PRPF18,NUP205,CHKA,MED10,ZRANB1,MCPH1,SLC12A2,ATP6V0D1,CSNK1G3,CREG1,NUDT4,RPL6,VKORC1,SLTM,EVC2,KLHL15,SIAH2,SLC16A1,EHD4,SNRNP70,C11orf1,APOL2,N4BP2L2,SNX27,CHMP2A,CORO7,FEZ2,UCK2,PMS2,UCK1,CLCC1,EXT2,MXD1,USP5,HNRNPA2B1,SAP130,NVL,PPP6C,CYB5R1,ZNF770,EBAG9,RNF25,PCGF6,METTL2A,FAM72B,PON2,HNRNPR,STAT6,HPS5,MAPK1,BRD9,TMEM33,NAT14,DNAJC2,TRIP12,SHPRH,SCYL1,VPS45,MYO9B,GFM2,SPPL2A,FASTKD3,FGFR3,MZT2A,PPIG,ZDHHC13,TMEM99,H2AFY,ATG13,NDUFS8,ERI3,FBL,SLC35A1,FRMD8,MICAL3,TGFB1,B3GALT6,ELOVL5,HEMK1,TIMMDC1,HELB,PSPC1,MIER1,SCFD2,NDRG3,ARL17A,CDK11A,MTMR3,ACAT1,CENPT,PLOD3,RAB3IL1,ZSWIM6,RAB14,ADD1,MRPS15,KDM4A,XIAP,DHX8,GLUD1,ANKRD23,PABPC4,CALM2,CDK5,PSMD1,NEK6,NSRP1,RABGAP1L,SRSF4,FNIP2,KCNAB2,PCBP2,MLST8,PLK3,ZNF672,HSDL1,MRPL43,TOPORS,MCL1,SMC2,PPFIA3,ICMT,SLC50A1,STOML2,LIMK1,ZNF689,PRDX5,ATE1,MLYCD,ATP6V0C,ST3GAL2,FBXL3,TFDP2,E2F2,PFKP,AAAS,DDX42,SSRP1,MRPL9,MRPS2,STRN4,TOP2B,ZNRF3,TMED3,DDRGK1,RAVER2,GNS,INTS7,INPP5A,MCM5,PHF14,ZNF326,UBE2QL1,NAGPA,TIMM8B,ETV3,TSPAN31,DHX29,TEX10,MAN1B1,RPS10,CBFA2T2,ABCF1,RHOB,LRRC14B,DTWD1,PTPRF,SCARB2,OSBPL11,CCDC86,DUSP3,SLAIN1,MDH1,HEXA,RNF139,SNX14,ZNF296,TRERF1,UBR2,CHD1L,ACTR3,WDTC1,MYH9,CREBL2,NIPA2,PRKACA,SAFB2,ANKIB1,STAM,ARL6IP6,RAB21,SP100,ZKSCAN1,DDA1,NUP107,ANKRD13C,MAVS,CEP63,TMEM136,RBM15,ATF2,DCTN1,SHOC2,PSRC1,MAP4K4,WBP2,ATP6V0A1,NDUFA7,DNAJA1,TAZ,C19orf54,TAF2,SEC61A1,WDR7,RPLP1,CBLN2,RBMS1,FUS,GEN1,LRP8,COIL,LRCH1,GALK1,ZNF786,RPS2,SESTD1,TRAK1,JMJD6,SIKE1,AKT1S1,KRI1,FBXO3,ERH,GATC,NDUFB4,PPP1R8,PRDM4,GTSE1,GEMIN6,DCP1A,SGCB,S100A6,IMPA2,NUDC,PDPK1,TK1,GUK1,TNFAIP3,GALC,ZNF512,KIAA0930,MRPS10,DDX39A,RPA1,ZNF180,ZNF862,KEAP1,POLE,TATDN2,PITX1,CAPN7,LRPPRC,PML,HMGB2,USF2,ANAPC4,SRM,DDX47,MCCC1,CDC42SE2,S1PR2,CDIPT,SEC16A,SSR1,LIN9,PCNA,ZNF639,TRMU,PIK3R2,ETV6,PPCDC,TXLNA,FAM86C1,MYBL1,MRPL32,CCAR1,ABCC5,PBXIP1,BAZ2A,TLK1,MRPL12,EZR,LNX2,LRP5,BRCA1,PRKRA,STX16,EPB41,OPTN,SEPT1,SOCS4,QRSL1,PIEZO1,OSGEPL1,GLCCI1,NUDT11,GEMIN7,SEPHS2,LZTR1,RACGAP1,PPP3CB,B4GALT4,RLF,RAPGEF6,SNRNP25,RB1,VASP,MED8,VMP1,PPIL2,MEA1,TIMELESS,AHDC1,ALDH18A1,TMEM8A,ABCC1,PREB,TRAPPC9,AACS,MEMO1,KRAS,RTF1,UBE4B,NFATC2IP,LY6E,ARPC1A,ZNF174,PSMC4,GOLGA4,PALB2,SYNCRIP,PRPS2,NIPA1,TIGD2,RNF114,FOXM1,MRPL39,XAB2,SUMO2,DUSP22,COMMD8,RPL11,CSDE1,MDM2,CORO1A,MINPP1,METTL9,POC5,DVL2,GM2A,PSMA8,COQ10B,CPOX,TIGD5,SLC26A6,CYP20A1,PRPF3,TXNL4A,RPSA,SRSF1,DNAJC10,SCAP,ZNF700,PLEKHG4B,TIMM17A,FAU,LTA4H,AP2S1,USP53,INTS2,CTDP1,MIF4GD,CDT1,ARID5A,SUMF1,GGA2,AP3S1,CSNK1A1,RMI1,TFRC,PTPN2,STARD9,IRF4,GSTK1,NDUFV1,SLC1A4,CWC27,SLC35B4,DDX31,ABCD1,RPAP3,CNTN5,SNX2,ZMYM5,CCDC34,CHCHD6,BSDC1,KPNA4,CDKN2AIPNL,FBXO41,BIRC5,TFE3,SNAP29,CDCA7L,PKD2,ACADM,CHMP7,SAT2,GCSH,ZNF496,TMEM109,TAP1,NHLRC3,IKBIP,EIF1B,ELMOD2,KIFC1,DBNDD1,CYB5RL,RNASEK,CDC25B,PRADC1,DNMT1,NOL12,ORAI2,USO1,AKT2,NOL8,GNG7,AURKB,MCFD2,SLC25A5,ZFAND5,MAK16,STT3A,TMED10,PSMD8,EIF2D,ITGB1,PTPN7,UQCRH,RRS1,ARRB2,RTN3,SVIP,DDX58,WSB2,PPIB,MUT,GMFG,HLA-E,NDUFA4,MAN2B1,METTL3,CFLAR,NDUFS4,RNF121,MEX3C,KLF16,HDAC7,DAD1,BDH1,PCYT2,GNAI2,ANKHD1,MORC3,TERF2,KCTD20,SEPT8,DCTD,PKM,TOMM40,PATL1,ADSS,SERTAD2,SERF2,ZFP92,NSF,DCK,ERGIC3,ACLY,LPCAT4,VCPIP1,YY1,PPP6R2,PPP6R3,MAP3K5,RNF14,CDK2,ZC3HAV1,SYS1,ZBTB37,URB2,EIF3D,MAGED1,KLHL18,ADPGK,SLC25A44,AP1B1,SDHA,PAIP2,PHC2,CRKL,TERF2IP,MOAP1,CYHR1,ZNF75D,SHC1,UCHL5,NAA35,TMBIM1,CCT2,CDKN2AIP,MKLN1,HMGN4,GALK2,CDC23,SHCBP1,AP4E1,PRDM11,VEZF1,PPP2R5A,ACYP1,STAT1,PPA2,TRIM32,RHEBL1,C1orf112,TCF3,MRI1,BRAP,AGPAT3,MYNN,SDF2L1,SPR,RAB11A,REEP5,FOXO3,MAD2L2,CCDC28A,PIP5K1C,RBM17,MAT2B,PTEN,CENPJ,TAGLN2,OSTC,CREB1,PACS2,NCOA2,SMC4,RNASEH2C,NEK7,NET1,PARP4,TBRG4,ANAPC2,RPL27A,YIF1A,SGSH,HGS,TTLL4,SLC38A7,MFAP1,CCDC69,BRWD3,ESYT2,SKA3,NPHP4,UBE2E2,HNRNPAB,PLXNC1,ST13,TMEM184B,DNAJC24,ZNF107,SLC29A1,KIF2C,AGFG1,SIRT2,FKBP2,USP48,SNRPD3,UBQLN2,CUTC,EDC3,UBLCP1,ZNF804A,RAP1A,THADA,EIF4A3,AP3S2,ATG3,DPYSL2,PPP1R12C,AKR1B1,NDUFB9,JOSD1,RP2,TTC4,TECR,ARID4A,FGFR1OP2,TIMM50,TDP1,DPM1,FOPNL,SLC16A7,WDR82,SLC25A22,STK17B,DHX15,CHAF1A,GEMIN5,COPS6,SASS6,RPS26,PSMC1,SLC12A7,TBC1D12,TM9SF4,ZNF768,UFC1,MED13L,TIA1,MEF2A,EPHX2,PITHD1,RHBDD1,NFATC3,BANF1,BUD31,ZNF335,YBX1,KNTC1,ACAD8,UBE3C,ZNF189,ALDH9A1,KDELR1,TSTA3,CIC,OXR1,PSMA1,SEPT7,TMEM241,NAP1L1,ODF2,EXOC4,KIAA1328,NUP62,PITPNA,NAA20,PTDSS1,MZT2B,PDSS2,C7orf26,TMEM106C,IMMT,ASH1L,CHERP,WDYHV1,PLAGL2,CHKB,IRF3,TWF2,PAIP1,ANKRD28,ANKLE1,FARSA,SAR1A,SCAMP4,APOOL,PDIA6,ACSL5,TOR1AIP2,AZI2,GFER,RAD54B,DAP3,TMEM41A,ZNF317,GADD45B,AKNA,REEP4,CBX4,MIF,KIF3B,GOLPH3L,SH2D3A,CASP6,TOR3A,SRGN,DBF4,MFSD10,SAC3D1,CTNNBL1,YIF1B,CLDND1,TTC17,SLC25A1,GINS1,PAQR6,CSNK1G2,TELO2,ADAM17,HMGN1,NASP,ASPM,PPP1R21,PRKAR1B,SYMPK,TARS,SNRPA,MAPK3,HSPA1B,HLA-B,ATAD2,PLAA,ZNF330,OSBPL8,KBTBD7,PREPL |
| 3.306e-08 | -17.22 | nucleoside monophosphate metabolic process | biological process | GO:0009123 | 261 | 74 | 17256 | 2622 |
COX15,NDUFA5,NDUFB6,UQCR10,UCK2,OLA1,UCK1,ADPGK,ATP6V1B2,ATP5PF,SDHA,DUT,UPRT,NDUFB9,ATP6V0A1,OGDH,NDUFA7,NDUFB1,TAZ,STOML2,NDUFA11,COX5A,DHTKD1,UQCRH,NUDT11,PFKP,NDUFV2,COX5B,GALK1,NDUFS1,MECP2,NDUFA4,COX4I1,CYCS,ATP5F1B,NDUFS7,HDDC2,NDUFS4,GART,NDUFV1,NDUFA2,NDUFB4,ATIC,MSH2,ATP6V0A2,NDUFS8,CYC1,NDUFA3,TGFB1,AMPD2,TK1,GUK1,NUDT4,LDHA,ADSL,DCTD,ATP5MF,PKM,HSPA1B,ADSS,ATP5MC3,PARG,DCK,PRPS2,COX7A2L,COX8A,IMPDH1,DNPH1,NDUFS5,ATP5F1A,GPI,PGAM1,NIPSNAP2,NUDT3 |
| 3.308e-08 | -17.22 | GO_REGULATION_OF_PROTEIN_UBIQUITINATION_INVOLVED_IN_UBIQUITIN_DEPENDENT_PROTEIN_CATABOLIC_PROCESS | MSigDB lists | GO_REGULATION_OF_PROTEIN_UBIQUITINATION_INVOLVED_IN_UBIQUITIN_DEPENDENT_PROTEIN_CATABOLIC_PROCESS | 102 | 38 | 17377 | 2626 |
GORASP1,CUL1,CCNB1,PSEN1,PSMD9,FBXO22,FBXO5,PSMD2,PSMA6,PSMD1,PTEN,ANAPC7,PDCL3,PLK1,PSMA8,PSMB7,PSMA1,ANAPC2,RAB1A,CDC23,PSMB9,PSMB3,PSMC4,CDC16,GOLGA2,CDC27,RPS27A,AXIN1,PSMD3,PSMD8,PML,CLU,SMURF1,UBE2C,PSMC1,RNF139,CDKN2A,ANAPC4 |
| 3.310e-08 | -17.22 | BLM (Bloom syndrome RecQ like helicase) | protein interactions | 641 | 131 | 47 | 17029 | 2761 |
COX15,FGFR1OP,CORO7,MECP2,SUMO2,XIAP,RMI2,BLM,UBE2I,RMI1,RPL23A,SF3B2,FAM192A,RPA2,PSMD1,EIF4A3,KLF16,RAD23B,XRCC2,MSH2,AKR1B1,UPF2,AQR,MSH6,TERF2,CARS2,TRIM8,SNRNP200,MIOS,ZNF512,TOP3A,BRCA1,CHAF1A,RPA1,CAND1,RPL37,ALDH3B1,FNTA,RPS27A,HPS5,PSMD3,FAAP100,RPS14,H2AFX,CHEK2,TERF1,RAD51D |
| 3.313e-08 | -17.22 | nucleotide metabolic process | biological process | GO:0009117 | 495 | 121 | 17256 | 2622 |
COX15,KARS,NDUFA5,PPCS,NDUFB6,UQCR10,MDH2,UCK2,OLA1,UCK1,SLC35B2,EFL1,ADPGK,ATP6V1B2,ATP5PF,SDHA,PARK7,MBD4,FLAD1,DUT,IMPAD1,ADCY9,PPCDC,UPRT,NDUFB9,SLC26A2,TALDO1,GPD1L,OGG1,KCNAB2,ADCY7,CGAS,ATP6V0A1,RRM2,OGDH,NDUFA7,NDUFB1,TAZ,PRPSAP1,PDHX,MPC1,STOML2,HINT1,GUCY1B1,NT5C3B,NDUFA11,COX5A,DHTKD1,UQCRH,MAPK1,NUDT11,PFKP,GALK1,NADSYN1,NDUFV2,COX5B,NDUFS1,MECP2,RRM1,RAB23,TKT,NDUFA4,COX4I1,CYCS,ABHD14B,ATP5F1B,NDUFS7,HDDC2,NEIL2,NDUFS4,ERH,NDUFV1,GART,NDUFA2,NDUFB4,ATIC,CTPS1,MSH2,TPST1,ATP6V0A2,NDUFS8,CYC1,NDUFA3,RNLS,LDHB,AMPD2,TGFB1,RHOA,TK1,GUK1,NUDT4,LDHA,NADK2,ADSL,DCTD,PKM,ATP5MF,PDE3B,HSPA1B,ADSS,MBIP,ATP5MC3,PARG,DCK,PRPS2,COX7A2L,ACLY,COX8A,TBPL1,NAXE,IMPDH1,ACAT1,MDH1,DNPH1,NDUFS5,GPI,ATP5F1A,NIPSNAP2,PARP10,PGAM1,NUDT3 |
| 3.356e-08 | -17.21 | GSE339_EX_VIVO_VS_IN_CULTURE_CD8POS_DC_UP | MSigDB lists | GSE339_EX_VIVO_VS_IN_CULTURE_CD8POS_DC_UP | 188 | 58 | 17377 | 2626 |
ZNF207,ZBED3,IER2,TSC2,MRPS26,CIB1,FLOT1,ASAH1,GLUD1,POMP,EIF2AK4,RGS2,TCF19,POLR3K,STAM,XPR1,NUDT19,ARL6IP1,TNPO2,H2AFY,ABCD1,MRPL40,SPTSSA,CDC5L,KDM3B,PTPN18,PPP1R18,POLR2G,CDC123,CIC,NEK7,DCAF8,PPP1R21,ITM2A,NUSAP1,SMC2,TRIM28,FADD,SMAD2,WAS,ORMDL2,TXNDC16,DDOST,HNRNPR,DHX16,TPP2,NAGLU,FAM3C,H2AFX,LRPPRC,SMAD1,TMEM159,RPS6KC1,CCNB2,TOB1,HDAC2,PTOV1,ADAM23 |
| 3.356e-08 | -17.21 | WELCSH_BRCA1_TARGETS_UP | MSigDB lists | WELCSH_BRCA1_TARGETS_UP | 188 | 58 | 17377 | 2626 |
SEPHS2,UBE2D3,NDUFS1,ADD1,SUCLG1,RHOC,HEXB,NDUFA4,HMGN3,KIF2C,RAB6A,ZNF267,CSNK1A1,WRB,SSR1,KIF5B,RAB8A,ADD3,RAB4A,PPP6C,ANXA5,KIFAP3,RBM3,CREB1,CITED2,TMED2,NIPAL3,COPS8,HMGN4,RAB7A,CIRBP,ATP6V0A1,RRM2,SRSF5,RAB1A,ARPC1A,HAGH,KIF11,RAB5B,PICALM,MAT2A,NEU1,ECH1,ADSS,CAT,KIF2A,PLD3,DDOST,JAK1,TMED10,GPS2,TIMM17A,STAT1,MPV17,PGRMC1,TAF12,SRSF3,TUBB |
| 3.358e-08 | -17.21 | GSE15330_GRANULOCYTE_MONOCYTE_PROGENITOR_VS_PRO_BCELL_UP | MSigDB lists | GSE15330_GRANULOCYTE_MONOCYTE_PROGENITOR_VS_PRO_BCELL_UP | 179 | 56 | 17377 | 2626 |
ZNF296,TP53RK,FAM207A,GORASP1,ADAM10,GPR89A,UROD,VTI1A,RACGAP1,CHAC2,ORC1,CUTC,SDHA,BZW2,MBD4,NDUFS4,KIFC1,UTP18,INTS7,TPST1,CTR9,FEM1B,MRPL54,GLE1,RNF26,LPCAT1,SLC12A2,SENP1,EEF1D,MYO5A,CSTF1,MAPRE2,RNASEH2C,TMEM39A,PSPC1,TYW1,GTPBP4,GALK2,IL12RB1,MTX1,FANCE,TARS,MFN2,ADSS,CDKN2AIPNL,ATP1A1,HSPBP1,STT3A,NIP7,NSMCE2,ACLY,TCOF1,CDK2,LRP8,HDAC2,GPR89B |
| 3.358e-08 | -17.21 | GSE13484_UNSTIM_VS_12H_YF17D_VACCINE_STIM_PBMC_UP | MSigDB lists | GSE13484_UNSTIM_VS_12H_YF17D_VACCINE_STIM_PBMC_UP | 179 | 56 | 17377 | 2626 |
DDX47,LIME1,MRPS2,SRSF6,UFC1,BABAM1,YTHDC2,TKT,OLA1,PCSK7,ARGLU1,CDK13,SECISBP2,CDIPT,OAT,SUPT7L,SLC12A9,PRKACA,TUBGCP2,NDUFS7,MAN1A1,SLC25A36,ANKRD26,HERC3,MTMR4,SEC24C,CORO1A,AQR,FBL,CITED2,EEF1D,AATF,EID1,BTAF1,ZMYND11,RPS24,DNAJC9,SRSF5,FXR1,MATR3,EIF3G,RPSA,AKAP1,CAT,ATP1A1,FASTK,AXIN1,PROSER1,PGRMC1,IARS2,ZDHHC7,PPP6R3,SMAD1,PARD3,DDX42,POLQ |
| 3.369e-08 | -17.21 | purine nucleotide binding | molecular function | GO:0017076 | 1854 | 367 | 17224 | 2647 |
RAB14,ABCC10,TAP1,DHX8,GLUD1,UBE2I,EEF2K,KIFC1,CDK5,NEK6,RAB4A,ATP13A3,PDS5B,DNM2,UPRT,SUCLG2,MAST2,PLK3,RHOBTB3,NRAS,AKT2,PBK,KIF15,MKI67,DDX20,SMC2,AURKB,MCM2,RFC2,RAB22A,RAB2B,ARF4,MAP3K4,MKNK1,KIF18B,LIMK1,MYO18A,RNASEL,LONP2,PFKP,DDX42,DDX58,HSPH1,RECQL,CHTF18,RHOC,TRIO,GSPT2,PRKAA1,DHX9,RRM1,RAB23,CERK,KIF23,TOP2B,EIF2AK4,RTKN,DDX56,SMC3,MCM5,EFTUD2,CTPS1,MSH2,DAPK1,RTCB,PIKFYVE,GNAI2,PHKG2,UBE2QL1,CARS2,DDX28,COQ8A,MAPKAPK3,DHX29,NOA1,PGS1,GTPBP4,PIP4K2C,SEPT8,RIT1,PKM,ABCF1,MAP2K2,CCT8,RHOB,PI4K2A,XRCC5,ADSS,EPRS,HSPBP1,NSF,CSK,CSNK1G1,DCK,QARS,ACLY,MAP3K5,CDK2,NRBP1,ACSF2,RHOG,KARS,ABCA3,TP53RK,RAB11B,RPS6KA1,RAF1,CHD1L,KIAA0232,ACTR3,RAC1,OLA1,TPX2,MYH9,EFL1,PRKACA,CBWD5,FLAD1,RAB21,PRKD3,ATP2A2,RALB,UBA5,ADCY9,CLCN6,SEPT11,TAP2,AQR,ARL5A,CDK12,ADCY7,CCT2,ULK3,ATP13A1,MAP4K4,TAOK1,PFKFB3,GALK2,PKMYT1,DNAJA1,RAB1A,MAT2A,DHX57,DDX17,KIF2A,RAD51C,HSPA4,JAK1,RAB24,GUCY1B1,HIPK2,CBWD1,PDXK,PPP5C,CSNK1D,TUBB,DYNC1LI2,RHEBL1,PRPF4B,POLQ,GALK1,ANXA6,TWNK,IP6K2,ATP5F1B,BLM,PMVK,IFT27,RAB11A,PIP5K1C,SRXN1,GATC,CBWD2,ARF5,TTLL12,MAP3K14,UBE2M,MSH6,SMC4,PDPK1,TK1,DDX24,GUK1,NEK7,BMS1,RHOT1,DDX39A,GUF1,KIF11,MARK2,MYO1F,GNA12,KIF18A,TTLL4,MAPK6,ASNA1,DDX5,DDX52,DDX47,UBE2E2,ST13,YTHDC2,MCCC1,CSNK2A1,UBE2Q1,UBE2Z,ABCB10,KIF2C,MAPK14,PAPOLA,ABL2,RAB8A,RAP1A,CDC42,EIF4A3,RAB35,TRMU,XRCC2,KIF22,RP2,EIF5,ABCC5,SRPK2,PLK1,LARS,SNRNP200,SEPT9,HARS,TLK1,CDC6,RAB5B,LSG1,STK17B,DHX15,RHEB,SEPT1,CHD3,IARS2,BAZ1B,QRSL1,ACTB,STK11,CHEK2,VPS4A,ROCK1,PSMC1,SEPHS2,UBE2D3,CDK13,THRAP3,RAB6A,CHKA,UBE2Q2,KIF13B,AHCY,ALDH18A1,N4BP2,CSNK1G3,ABCC1,NTPCR,AACS,ACSL3,KRAS,MAP4K3,EIF2AK1,UBE4B,SEPT7,DAPK3,BBS12,MASTL,PSMC4,GNAS,PRPS2,NLRC5,SIL1,RUVBL2,ATP5F1A,MYO9A,EHD4,PMS2,UCK2,SMARCA4,RRAGC,UCK1,CHKB,ORC1,ATP6V1B2,LYN,TWF2,CHD1,MIEF1,FARSA,PDK2,IARS,SAR1A,NVL,KIF14,SCYL3,ACSL5,CLCN3,CGAS,RAB7A,ARL5B,RAD54B,DAP3,ATP1A1,IDE,DHX16,CLK3,STK38,FASTK,XRCC3,MAPK1,ABCA1,RAD51D,KIF3B,NADSYN1,SHPRH,TOR3A,GNE,SCYL1,SMC6,ARFIP2,ARF1,MYO9B,CDK11B,CSNK1A1,SCYL2,PIP4K2A,GFM2,WRNIP1,KIF5B,GTPBP3,STARD9,FGFR3,GART,GRK2,ABCD1,DDX31,CAMK2G,MYO5A,CSNK1G2,RHOA,PRKDC,HELB,BTAF1,ATP2C1,ABCF2,TUFM,PRKAR1B,NADK2,PNPLA8,RHOT2,CDK11A,TARS,MAPK3,DDX23,HSPA1B,MFN2,RAB18,NEK1,UPF1,ATAD2,UBE2C,RPS6KC1,HRAS,HIPK3 |
| 3.386e-08 | -17.20 | mitotic spindle organization | biological process | GO:0007052 | 82 | 33 | 17256 | 2622 |
BCCIP,ZNF207,KIF3B,MZT1,MECP2,POC1A,DCTN2,XIAP,TPX2,KIF23,RACGAP1,NUF2,CCNB1,STMN1,RAB11A,BIRC2,TUBGCP2,KIFC1,ABRAXAS2,PRC1,RHOA,BIRC3,INTS13,MYBL2,TUBGCP5,AURKB,KIF11,KIF2A,GOLGA2,BIRC5,MAP4,CHEK2,WDR62 |
| 3.484e-08 | -17.17 | GO_NEGATIVE_REGULATION_OF_PROTEIN_COMPLEX_DISASSEMBLY | MSigDB lists | GO_NEGATIVE_REGULATION_OF_PROTEIN_COMPLEX_DISASSEMBLY | 157 | 51 | 17377 | 2626 |
ZNF207,KIF3B,ADD1,DCTN2,CIB1,XIAP,TPX2,KIF23,MYH9,RACGAP1,HAUS4,CCNB1,TWF2,STMN1,RAB11A,BIRC2,TUBGCP2,HAUS2,SPAG5,FBXO5,KIFC1,STARD9,SMC3,NEK6,CAPZA1,PRC1,ARHGEF2,CEP63,SPTAN1,RHOA,BIRC3,ASPM,NEK7,TUBGCP5,MYBL2,EZR,AURKB,CAPZA2,KIF11,HAUS8,KIF2A,MID1IP1,GOLGA2,BIRC5,CHD3,MAP4,CHEK2,WDR62,ESPL1,CSNK1D,TUBB |
| 3.484e-08 | -17.17 | GO_REGULATION_OF_NUCLEAR_DIVISION | MSigDB lists | GO_REGULATION_OF_NUCLEAR_DIVISION | 157 | 51 | 17377 | 2626 |
ZNF207,CHMP2A,PDCD6IP,GORASP1,PHB2,PTTG1,CENPF,CSNK2A1,CDK13,SIRT2,CCNB1,BECN1,MAD2L2,FBXO5,RB1,PDXP,NEK6,CDC42,PTEN,PIN1,MSH2,H2AFY,KNTC1,TGFB1,PLK1,PPP1R9B,CUL3,LRP5,NUSAP1,CDC6,PKMYT1,CDC23,CHMP2B,ANLN,RAB1A,BORA,KIF11,DAPK3,CDC16,GOLGA2,CDC27,BIRC5,NSMCE2,CDCA5,CHMP4B,XRCC3,GEN1,UBE2C,TERF1,ESPL1,ANAPC4 |
| 3.520e-08 | -17.16 | REACTOME_TRANSLATION | MSigDB lists | REACTOME_TRANSLATION | 144 | 48 | 17377 | 2626 |
RPS15,RPS2,RPLP2,SEC61G,EIF3D,GSPT2,RPL15,RPL11,SSR1,RPL23A,SEC11A,RPN1,EIF2S2,RPL17,RPL19,RPN2,EIF5,PABPC1,EEF1D,SRP72,RPL29,RPL35,SEC61B,RPS10,RPL6,RPL8,RPL38,RPS24,SSR2,RPL27A,EIF4H,RPS9,EIF3G,RPSA,EIF3A,EIF3H,RPL36,RPL37,EIF3K,SEC61A1,RPL32,DDOST,RPS27A,RPS14,RPLP1,SPCS3,FAU,RPS26 |
| 3.566e-08 | -17.15 | breast | COSMIC cancer mutations | breast | 16905 | 2554 | 17385 | 2587 |
HECA,ZBTB10,ABCC10,HEXB,TGOLN2,CCNL2,FBXO22,EEF2K,THAP4,RAD23B,ATP13A3,DNM2,ZNRD1,FTSJ3,USP34,CCDC57,ERCC1,NRAS,EHMT1,KIF15,HNRNPF,WDHD1,MIER2,DIDO1,MCM2,RAB22A,SMAD2,MID1IP1,RPS27A,MYO18A,OGT,MPV17,COX5A,SMAD1,ZNF75A,ANXA11,SLC25A33,ZNF720,SEC61G,GGA1,MUM1,CCZ1,TRIO,CUTA,RAB23,KCTD17,HAUS4,EIF2AK4,APH1B,PARN,CDC73,MYL6B,ATG4A,TMEM179B,ERV3-1,PDXP,SMC3,C4orf3,GEMIN4,MVP,NUP85,PPP6R1,PABPC1,NSUN4,PPA1,IFRD1,AGGF1,FOXK1,RBM42,GTPBP4,MAP7D1,MRPL16,ELK1,EIF4H,RDH11,MAGED2,KPNA1,ETS2,TYW5,WIPI2,RUFY3,PDLIM5,ACSF2,FAM72D,RHOG,EXOC3,STARD7,VTI1A,INO80E,SLC35B2,LCLAT1,RCOR3,CPNE3,KIAA1147,RBM23,ZNF420,AHCTF1,TBC1D22A,TBC1D14,GMEB1,NSFL1C,SEPT11,GPD1L,ZC3H3,ARL5A,PDCL3,SNX8,ERMP1,EID1,IDH3A,POLR2D,HTATIP2,MEF2D,TMEM147,GSTCD,TANC1,MAT2A,VPS26B,CORO1C,NSMCE2,CAMKMT,PPP5C,PITRM1,TUBB,COMMD10,ZNF445,SRSF6,HABP4,CCM2,FLOT1,BTN3A1,ATG2B,ABHD14B,PPP1R3B,GOLM1,ZBTB45,HUWE1,ZNF260,NAA50,ANXA5,LTN1,UBE3B,NAP1L4,ZNF710,ST8SIA2,RPL22L1,MED22,SPTAN1,STAU1,TCTEX1D2,DDX24,TACC1,MRS2,LDHA,HEBP2,LLPH,RAB3IP,TTC33,PICALM,SH3BP5,SLC19A1,ACOX1,FAM3C,AEN,PARP10,YWHAH,THAP5,GPATCH4,FAM129A,TRIM11,YTHDC2,SNX15,RBM8A,ENSA,NENF,SND1,RUFY1,TRIM65,ZER1,PRNP,KRR1,RAB8A,NUP210,NT5DC1,NOC2L,EIF5,TACC3,RYBP,VPS13B,PTPN18,MIOS,MBLAC2,SNRPB,CDC6,UTP3,PBRM1,ODC1,USP21,TRAM2,FBXO28,BCL7C,ARRDC1,ADAM9,DVL1,NUMB,ZNF564,FUBP1,C1orf74,CTU2,PARP12,ZCCHC9,CENPF,LAMTOR3,CHCHD2,NCKAP1,LYRM2,RSAD1,TNS3,SUB1,RINL,SSBP3,KIF13B,MBD2,XPA,AHCY,RBM3,GLE1,MRPL48,LRSAM1,HDHD2,NTPCR,NSDHL,AMD1,CAMSAP1,ZNF761,METTL22,ICAM2,STYXL1,APPL1,BBS12,ANKRD46,RXRB,SDHB,PCM1,GALNT2,TMEM168,NLRC5,RUVBL2,MYO9A,BTBD10,CCNB2,USP7,GLT8D1,RPLP2,SUCLG1,ARID2,TMX4,SLC2A1,ATP6V1B2,PCBP1,LYN,BCAP31,VAV1,TMEM69,MRPL50,PSMA6,ZNF473,ZNF302,BRPF3,TARDBP,BCAP29,CTDSP2,PRPF19,PPIF,KDM3B,MND1,CLCN3,BIRC3,RAB7A,ANKRD33B,PPIE,CHMP2B,VDAC1,EIF3H,TMEM201,GLOD4,IDE,DHX16,UHRF2,CHMP4B,XRCC3,PARD3,BCL2L12,MCM10,C19orf53,KLHL21,PDAP1,TMX3,CDCA8,GTF3A,ARF1,SLC12A9,TUBGCP2,DNAJB9,HOMER1,POLR1B,RNF5,RBM15B,PPAN,RHOA,RPRD1A,BTAF1,TOP3A,ARHGEF12,PCGF1,DDX23,RAB18,CACNB1,TRIM26,PDCD6,ATP6V1D,L3MBTL3,FAM110A,NEIL3,CTBS,BBX,IMPDH1,TAF12,NR2F2,PGAM1,HIPK3,IFI16,NUP188,TXN,H2AFZ,PNISR,TMEM203,PRKCSH,USP39,UBE2I,PARK7,SLC25A37,ASPHD2,ZNF428,RAB4A,TRA2B,SUCLG2,TAF5L,SMARCE1,ZNF800,CDC5L,ZNF524,SGCE,OSBP2,NSUN2,USP22,CLNS1A,EIF3A,ZMYM3,DOT1L,IWS1,ANKRD10,WAS,KIF18B,TPP2,C1orf109,ZMAT3,B4GALT2,PRPF38B,RECQL,C9orf78,EWSR1,GADD45G,RRM1,ACAP1,B4GALT1,CYCS,FAM136A,SUPT7L,TMEM165,CNOT3,NPLOC4,WDR48,SPAG5,RTKN,CEP104,EXOSC7,KLHL5,LRRC8D,PPP4R1,MSH2,PIGG,FBXL7,OSTF1,MRPL40,TNRC18,SYTL3,FAM171A1,APOL1,EIF5A,GCC2,PRIM2,ELL2,RDH10,MFNG,RPS24,GORASP2,CAPZA2,ADRB2,CCT8,MTR,PHF6,PFDN5,SLCO4A1,TTC13,GOLGA2,RBMX,MED15,PIAS2,APPL2,SAMD8,CDKN2A,NUDT3,ZNF511,ATXN3,RAF1,KIAA0232,C2orf49,CD320,EPM2A,CCNA2,MTMR4,BRI3,TP53BP2,AQR,RBM12B,ILKAP,CDK12,SAP30,BRD4,DRAP1,NARF,LRRC8A,ELP4,ABHD11,PKMYT1,ASB13,SERP1,TRIM28,SUPT16H,EIF3K,CHMP4A,CBWD1,ATF6,XRCC4,ADAM23,PRPF4B,NDUFS1,DEPDC1,MECP2,SECISBP2,HMG20A,WWP2,JAKMIP1,SLC25A36,CCNK,DNAJC8,ELP5,AXIN2,CITED2,JMJD4,ANKRD37,KAT2A,TMEM126B,RABIF,ADSL,PACS1,BMS1,KCNQ1,OTUD3,ARSK,MACF1,KIF11,KLF6,COMMD4,SMAP2,FADD,SH3GLB1,MYO1F,CBX3,TMEM127,INF2,PPP1R11,DUSP11,DDX5,WDR62,TAF6,ESPL1,PURA,DDB1,DEF6,IPO4,FAM83G,UBL3,PIGM,NAT9,LYRM4,GPR132,UBE2Q1,PTP4A3,BRIX1,MRPL19,ZNF696,SF3B2,PCYOX1L,CDC42,SYNM,GOT2,JAZF1,HADHB,RPF2,SLC35C2,CNNM3,CARM1,SRPK2,WDR41,LARS,ZCCHC10,CCDC138,LRBA,TMEM216,SUMF2,KMT2C,OGFR,PRPSAP1,ASF1B,RPL37,MAN2A2,EIF4ENIF1,NIP7,U2SURP,MIA2,ZNF268,VPS4A,ATP6V0E1,PPP1R2,PM20D2,XPNPEP3,RGS2,LYAR,FAM89B,POLR2I,TRAFD1,SUGP2,GBA,EIF2A,SYVN1,DAPK3,ARHGAP15,MASTL,UAP1,NFIL3,FN3KRP,YWHAZ,CTSA,TMEM14A,TOB1,TSEN15,ADNP2,TCF12,PRKAB1,MDH2,SMARCA4,ORC1,RRN3,UBXN2A,IARS,CD3EAP,KIF14,EXOSC1,CS,CLTB,DNAL4,CSTF1,POU2AF1,UBQLN4,NXT1,HPDL,PGGT1B,SELPLG,SMU1,ATXN1,GLO1,OGDH,BICD2,CADM1,EDEM2,HERPUD2,TOLLIP,FANCE,MBD3,PDHX,RPS9,ALKBH6,SURF4,DUS3L,ARNTL,ANP32E,FKBP5,TMEM101,CCDC125,ABCA1,PDCD2L,GCLM,RAE1,DCTN2,NUP54,CHIC2,PAWR,MXD4,DCUN1D4,PIP4K2A,XPR1,FERMT3,KIF5B,KLHL20,SEC24C,RRBP1,ARHGEF2,ANP32A,LDLRAD3,C12orf75,STAT3,MYO5A,NIPAL3,AMPD2,TXNL1,PHF20L1,DCAF6,FAM49B,TMEM39A,ATP2C1,RFFL,COG1,RCOR1,PRMT2,TFEB,LEMD2,SERF1B,UPF1,ELMO1,ZC3H7B,DTX4,ZMIZ1,TERF1,HRAS,CCDC93,FGFR1OP,TMED7,PIGQ,AGPAT1,CNTROB,PPP1R16B,MIS12,GSDMB,TTC9C,PDS5B,NUP153,SENP1,PGAP2,TMEM115,PLEKHM3,DCUN1D5,PLEKHF2,BRMS1,PWWP2B,TRIM47,WDR11,AXIN1,SMG9,TRIM52,LONP2,NDUFV2,PHF23,CERK,SLC4A2,EZH1,ITGB5,LMNA,MCTS1,DDX56,EIF2S2,SLC38A5,FOXN2,CARS2,PRRC2A,C16orf72,RB1CC1,ZMYND11,PGS1,MYBL2,UHRF1BP1,SRSF5,MPG,MATR3,CYB5A,NCDN,POLR2J,SETD3,TEX30,CNOT6,NDE1,EGLN1,ZNF207,ANKRD27,PPP1R37,ABCA3,SARNP,IVNS1ABP,MON1B,RMI2,TMEM97,NIT2,NUF2,ZNF267,TCF19,TMEM161B,KTN1,APP,PRKD3,CLUAP1,ATP2A2,UTP18,GRSF1,DUT,ZCCHC2,ANAPC7,RNF19A,FAM76B,CLN6,TMEM9,GCC1,RNF169,ADCY7,ATP6V1G1,ENPP4,RNPS1,CDCA2,FKBP3,GPR137,DDX17,CHCHD3,PEX5,CDC16,HIPK2,MBOAT1,TICAM1,PDXK,ZBTB11,ANXA6,TMBIM4,GMCL1,UBE4A,IL21R,ETS1,WRB,ZNF92,PNO1,CAPN2,ADD3,SUV39H2,TTLL12,TPCN1,TMX1,HNRNPM,LYPLA2,MFSD12,LDHB,PPP3CA,NUDT8,POLK,JTB,EMP3,MTMR12,ZP3,PDE3B,KIF18A,CCDC6,WNT5B,MAPK6,LY75,C4orf46,SLC25A19,RGL1,PSAP,WDR76,IGBP1,FAF1,SNAPIN,COX15,AGRN,THOC1,GNPDA1,GPBP1L1,PPP1R15B,CSNK2A1,EBNA1BP2,GIT2,BIRC2,ATPAF1,DLG5,ABL2,XRCC2,ZFYVE27,MCMBP,PTPRK,CDC37,SP3,METTL1,EXOSC6,HARS,GMFB,ESYT1,ANLN,RAB5B,RHEB,DPYSL3,TBC1D17,TIMM13,CDCA4,TONSL,NRM,NAGLU,ACTB,ZNF45,TMUB1,CTCF,ASAH1,DOCK11,CRLF3,ASXL2,LRRC14,NUS1,SLC27A4,AFF1,MDFIC,MAML1,CYTH1,NQO2,UTP15,EIF2AK1,EIF4G2,ZDHHC3,MOSPD3,ITPRIPL1,CDC27,SNAP23,TBPL1,PRMT7,KCTD7,NDUFA5,CYLD,UGP2,DYNLL1,COPE,HCFC1R1,ZADH2,GGPS1,RPAIN,RAD23A,ATP6V0B,PDK2,STRBP,DUS4L,MRPL34,PDCD2,SAP30L,CLPTM1,SLC39A9,RPL29,RPL35,BTG2,DNAJC9,FRAT2,MTMR6,NFATC2,KDM1B,ARL5B,USP36,CCDC127,MRPL2,ATP1A1,CLK3,MAFK,PSMD3,NDUFA11,CEP55,ZNF436,DNAJC17,NCOA1,SLC25A39,ZC3HC1,ZNF146,ATXN7L2,CDC40,SMAP1,GOLIM4,RRP15,DAP,GNE,SMC6,ARFIP2,NKRF,CHAC2,BZW2,WRNIP1,SS18L1,CENPM,PTGES3,CAMK2G,MLEC,ZNF202,PPWD1,FAM50B,RHOT2,NEU1,TPD52L2,GOLGA7,TWSG1,GLG1,PGRMC1,FAM126A,RPS6KC1,UBE2C,PPCS,NDUFB6,TMEM41B,ZDHHC8,PLXNA1,CCNB1,SLC20A1,COMMD6,ABHD14A,POLR3K,C14orf119,ASAP2,SNUPN,CNPY4,PLCL2,TFG,SEH1L,ATG9A,PBK,MKI67,DDX20,AMDHD2,SLC17A5,GALNT7,CCNF,FOXRED1,RBM47,PTER,WDR4,DHTKD1,TRAF5,HDAC2,PWWP2A,HSPH1,LIME1,MAPRE1,CHTF18,KIF23,SLC35B1,NOTCH2,PMF1,JMY,FKBP1A,SLC31A1,SNX18,ATIC,CTPS1,ATP6V0A2,PIKFYVE,RNF135,LPCAT1,EEF1D,TMED2,PHF10,FTL,DDX28,ZNF84,SIGMAR1,PIP4K2C,FAM133B,RIT1,PLEC,KDM3A,SF3A2,FAS,EPRS,ZNF777,TMEM54,QARS,PPP3R1,TCOF1,NRBP1,CABLES1,DNMT3A,RWDD1,CKLF,TRIP10,SF3B1,RPS6KA1,CAST,SUZ12,RAC1,GPR89A,OLA1,SNN,GNB2,FLAD1,APLP2,KDM2A,TNPO2,CDKN1B,TALDO1,GPX4,ATP13A1,MAPRE2,RFC3,ERF,CUL3,SLBP,KIAA1586,H2AFV,POLG2,GAR1,PSMB9,DHX57,NSA2,HSPA4,MRPL55,JAK1,TBL3,GOLGA8A,SEL1L,H2AFX,KLHDC4,B4GALT3,PDCD11,ATMIN,POLQ,POU3F2,OTUD5,NCOR2,ANKRD13D,PKP4,SCAMP3,BABAM1,CDCA3,SLC25A12,BLM,TMCC3,GTF2F1,RPL17,CRAT,AHSA1,PRC1,UPF2,COPS7B,SLC38A10,CNOT6L,CNPY3,UBE2M,IFT46,TMEM160,TSHZ1,ZFP64,DENND4C,DENND1B,WDR18,RPL8,ILF3,LRRC1,RHOT1,TSR2,MARK2,ECH1,PRDX1,PLD3,NUCB1,GNA12,FBXO21,C1orf131,PRDX3,PFDN4,HNRNPH3,STX18,TFDP1,KHSRP,ASNA1,CPEB2,SSSCA1,VPS29,BYSL,S100PBP,MIB2,IER2,PTMS,NOP2,UBN1,DCAF15,NF1,ALKBH5,MOGS,UBE2Z,TAF6L,BECN1,MAPK14,SNAPC4,RNF103,BCAT2,MBD4,METTL14,ZNHIT6,IMPAD1,RCSD1,PHTF1,SRI,KIF22,ZBTB22,NFU1,OGG1,TRIM14,ELOF1,COPS8,FYTTD1,TRIM8,RRM2,SOX4,ABHD5,CXXC4,UBTF,PAF1,UEVLD,SPATA2,PQBP1,IARS2,ATXN2L,GALNT10,STARD3NL,RPS15,PIGN,AGTRAP,CIB1,XPO7,SRRT,ZNF449,CAPZA1,GLTP,BCL2,KIFAP3,N4BP2,HP1BP3,VOPP1,THNSL1,ISG15,CAND1,GNAS,TSC1,RBM25,CDCA5,ZFP90,NANP,RBBP4,ZBTB24,SMARCD1,MBD1,WASF2,MMACHC,TOMM20,IFI27L1,GNPNAT1,MPHOSPH8,HNRNPUL2,CHD1,MEAF6,C2orf68,CCDC50,AKAP8,PARL,RPN2,CHTOP,FAM3A,F2R,SCYL3,TMEM14C,ABI1,HTRA2,MOSPD1,RLIM,FAM172A,ZNF500,PSMB7,NLN,WIPF1,BOLA1,BUD13,NDUFB1,PEF1,EIF3G,BTBD1,TAB2,CHCHD1,TULP3,WDR59,CANT1,SCARB1,GAS2,USP11,SMURF1,TSPAN5,PPP2R2D,CDS2,MAGEH1,MRPL42,EYA1,CDK2AP2,MRPS26,LETMD1,KLF13,HDDC2,RGS1,MAN1A1,FBXO5,GART,PELO,TANK,BRD7,MRPL11,SAMD4B,ZDHHC18,GTF3C6,POLR3GL,WDR81,MEN1,ZNF407,MFN2,COX8A,ZRANB2,MBD6,SRSF3,ATP6V1C1,IDH3B,TATDN1,TSC2,LACTB2,CMTM6,RBM4,ANKRD39,ZNF275,RPL23A,CDKN2C,NAPG,USF1,DNAAF2,MECR,AP1M1,UPRT,CRY2,ECD,RNF26,MOB1A,TIPARP,LRRC59,ANKRD9,MGAT5,RHBDD2,BAK1,ZNF559,RHOBTB3,GABPA,NUTF2,WBP1,GINS4,ARF4,KRIT1,BOLA3,AHNAK,RAD18,PDRG1,RNASEL,CHPF2,OAZ1,SMNDC1,PDCD4,NXT2,HIVEP3,KIAA0100,CLSPN,RHOC,DHX9,PDCD7,PSMD9,HAUS2,COPB2,TFAP4,CD59,RNFT1,RIMS3,MEGF8,FBXO7,EFTUD2,MRPL21,CPSF4,PHKG2,LUC7L2,SRSF11,EIF3L,MTA2,TYW1,USP10,ITM2A,SSR2,BCLAF1,MTX1,SFXN5,FNTA,PDLIM1,TXNDC16,TMEM159,ZNF830,MRPL3,ALS2,FAM72A,TRIM41,KARS,NQO1,POC1A,PTTG1,ANK3,TPX2,TBC1D13,DAZAP2,STMN1,GLRX3,C19orf48,CBWD5,REPS1,ABHD16A,FBXL6,SH3BP1,MTA1,UBA5,CLCN6,INTS12,RPRD1B,SZRD1,CGGBP1,CPNE1,SEC61B,POLR2L,FAM118B,GOPC,CRNKL1,E2F3,CIRBP,RPL38,PFKFB3,GORAB,RAB1A,GIGYF1,TMEM184C,PPP2CA,KIF2A,CCDC14,LSM6,RNF38,DMWD,SNRPG,CENPBD1,USP13,ZFP91,TRMT6,IP6K2,WDR5,SLC25A43,IFT27,PMVK,RRP36,NEIL2,SRXN1,RPA2,PSMD2,CLIC4,PDCD10,ITGB8,CBWD2,COQ4,ARF5,ARHGEF1,FBXL19,GTF2H2,TTPAL,UTP20,MAGT1,GPS2,DBI,MRFAP1L1,SSNA1,CD81,TMEM131,WDR13,FANCI,PAPOLA,CREM,FANCL,TET3,GLIS2,IL6ST,INTS1,POP7,SLC44A1,MTPN,ASB6,PLK1,RPP25,SEPT9,CELSR2,RBX1,APH1A,RAD51AP1,ZBED5,CKAP2L,PSMG1,UBE2V1,IL12RB1,EAF2,KRTCAP2,LUC7L,LSG1,NECAP2,C1orf122,ALG3,TRIM4,AGPAT2,CHD3,ZNF367,E2F4,PRPF4,KPNA2,BEND6,CLN3,DNAJC30,FAM208A,NGLY1,POT1,MYL12B,CCDC137,RMND5A,HJURP,PHB2,FAM53C,DNAJB2,NKD2,SDC2,KLC1,CDK13,ADCK5,COX4I1,RAB6A,DNAJB1,ARID1B,C1GALT1,MLX,UBE2Q2,CCP110,ZNF746,ARL6IP1,CTR9,NIPSNAP1,ABHD2,DCAF8,ACSL3,LDB1,MAP4K3,ARMC8,IRF5,NMT2,RPL36,HAUS8,MBIP,ORMDL2,COX7A2L,ZDHHC7,FAM122A,SIL1,DTD1,UNC13C,BCCIP,SART1,TRAF7,NDUFAF2,TOR1AIP1,ZNF416,LAGE3,ZFYVE21,TM9SF3,RRAGC,ZNF121,OIP5,NRF1,WDR44,PIN1,PPME1,EFCAB11,RPAP1,CABLES2,TOP1MT,LMAN1,AHCYL1,STRAP,SPSB3,ZNF583,SNX25,ARHGAP17,POLR2G,KIAA0040,ZNF780B,PPT1,NUP155,DCLRE1C,MRPS14,RHBDF2,SUGP1,RBL1,FASTK,UBXN2B,STK38,AP1S1,SPRYD4,SLC22A23,H3F3A,CHID1,SMAD4,RAD51D,SLC30A9,NADSYN1,UNK,CMAS,HMGN3,NCAPG,SCYL2,FZD6,HERC3,GTPBP3,CTSS,ORC3,RNLS,YTHDC1,ACP2,CSRP1,HMGN5,METTL5,ABCF2,TUFM,RANGAP1,PNPLA8,HAGH,API5,ZFR,SEC23IP,E2F1,USP20,TMEM219,RBPJ,MAX,PDCD6IP,LUZP1,GXYLT1,ADAM10,CXXC1,TSC22D3,AP3M2,CUL1,GYG1,NANS,OAT,MYEF2,ANKRD26,PA2G4,NOL11,FIZ1,ZNF200,MARCH2,SLC26A2,SRSF10,SRP72,KLF10,LACTB,CBFB,RFC2,RAB2B,PRIM1,MAP3K4,HHEX,RPS14,LUC7L3,MAP4,MRPL27,BTF3,PTPDC1,CCDC59,NMD3,PTOV1,COX5B,DNAJC5,SCOC,DHPS,POLR2K,ANKH,C16orf87,VAV2,PRKAA1,GSPT2,DLGAP4,TATDN3,PXMP2,PRPF39,PSEN1,ZNF79,PDXDC1,VPS25,NDUFS7,YY1AP1,C12orf10,FAM192A,RPN1,LHX8,ARPC5,ZNRF2,DAPK1,TPST1,PIK3IP1,CYC1,SOCS5,FDFT1,PIGT,WDR1,EMB,ZNF574,C1orf35,EXOSC9,ARID1A,PTTG1IP,C9orf40,FXR1,GOSR1,MAP2K2,TWISTNB,AKAP1,XRCC5,HMGN2,PI4K2A,SEC31A,CAT,DERL1,MTHFD2,HSPBP1,CEBPG,ARAP1,FAM83D,USP32,CABIN1,SMPD4,GPI,CYTIP,TP53RK,REPS2,RAB11B,UROD,SLC39A13,POMP,BCL2L1,DECR1,RALB,SIAH1,LPIN2,ADCY9,SOCS6,MRPS27,TTC3,RNASEH2A,CFL1,ANKLE2,CDC123,OAF,VDAC2,EDF1,ERC1,EML4,AMZ2,ANKZF1,ZNF282,RAD51C,DSN1,DDOST,HINT1,DGCR8,SAFB,HAGHL,LMBR1,FTSJ1,RWDD4,NCLN,BEND3,EYA2,DYNC1LI2,SLC41A1,B4GALT5,MANBA,TKT,FAM76A,CBLL1,ARGLU1,LANCL1,POFUT1,FAM8A1,HEATR5B,HLA-A,EBP,RFWD3,NDUFA2,FUT8,FJX1,BTF3L4,PTPN11,MRPL54,FEM1B,RPL19,CNN2,NDUFA3,MTX2,MSH6,PDLIM2,LONRF3,RFXANK,FBXO9,GUF1,RPL32,ZHX1,OAZ2,NDUFS5,WDR91,GPR89B,HIGD2A,ZBED3,RORB,POLA2,ZNF76,MTX3,COPA,UQCR10,HMGXB3,PHRF1,ABCB10,COMMD5,MAP1LC3B,DST,SIVA1,RAB35,GPATCH1,TCEA1,DRAM2,DEAF1,SNRNP200,NCK1,LAP3,VHL,SREK1,ARHGDIB,PITPNB,HSPB11,BRWD1,PPM1G,SH3GLB2,CRCP,BAZ1B,CAB39,ACBD4,STK11,CLU,CHEK2,ZSWIM3,TSTD2,CHPT1,MRPL13,DCAF5,CAPN1,UBE2D3,NSMCE4A,PPP1R12A,ZCCHC8,GORASP1,NACA,UBXN1,C19orf25,PCSK7,EPN1,RPL15,THRAP3,TTF1,QSOX2,NUP205,PRPF18,CHKA,DTL,MED10,ZRANB1,MCPH1,SLC12A2,ATP6V0D1,CSNK1G3,CREG1,NUDT4,RPL6,VKORC1,SLTM,EVC2,KLHL15,SIAH2,SLC16A1,EHD4,SNRNP70,C11orf1,APOL2,N4BP2L2,SNX27,CHMP2A,CORO7,FEZ2,PMS2,UCK2,UCK1,CLCC1,EXT2,MXD1,USP5,HNRNPA2B1,SAP130,NVL,PPP6C,CYB5R1,ZNF770,EBAG9,RNF25,PCGF6,METTL2A,FAM72B,PON2,HNRNPR,HPS5,STAT6,MAPK1,BRD9,TMEM33,NAT14,DNAJC2,TRIP12,SHPRH,SCYL1,VPS45,MYO9B,GFM2,SPPL2A,FASTKD3,FGFR3,MZT2A,PPIG,ZDHHC13,TMEM99,H2AFY,ATG13,NDUFS8,ERI3,FBL,FRMD8,SLC35A1,MICAL3,TGFB1,B3GALT6,ELOVL5,HEMK1,TIMMDC1,HELB,PSPC1,MIER1,SCFD2,NDRG3,CDK11A,MTMR3,MEGF9,ACAT1,CENPT,PLOD3,RAB3IL1,ZSWIM6,RAB14,ADD1,MRPS15,KDM4A,XIAP,DHX8,GLUD1,ANKRD23,PABPC4,CALM2,CDK5,PSMD1,NEK6,NSRP1,RABGAP1L,SRSF4,FNIP2,KCNAB2,PCBP2,MLST8,PLK3,ZNF672,HSDL1,MRPL43,TOPORS,MCL1,SMC2,PPFIA3,ICMT,SLC50A1,STOML2,LIMK1,ZNF689,PRDX5,ATE1,MLYCD,ATP6V0C,ST3GAL2,FBXL3,TFDP2,E2F2,PFKP,AAAS,DDX42,SSRP1,MRPL9,MRPS2,STRN4,TOP2B,ZNRF3,TMED3,DDRGK1,RAVER2,GNS,INTS7,INPP5A,MCM5,PHF14,ZNF326,UBE2QL1,NAGPA,TIMM8B,ETV3,TSPYL4,TSPAN31,DHX29,TEX10,MAN1B1,RPS10,CBFA2T2,ABCF1,RHOB,LRRC14B,DTWD1,PTPRF,SCARB2,OSBPL11,CCDC86,DUSP3,SLAIN1,MDH1,HEXA,RNF139,SNX14,ZNF296,TRERF1,UBR2,CHD1L,ACTR3,WDTC1,MYH9,CREBL2,NIPA2,PRKACA,SAFB2,ANKIB1,STAM,ARL6IP6,RAB21,SP100,ZKSCAN1,DDA1,NUP107,ANKRD13C,MAVS,CEP63,TMEM136,RBM15,ATF2,DCTN1,SHOC2,PSRC1,MAP4K4,WBP2,ATP6V0A1,NUSAP1,DNAJA1,NDUFA7,TAZ,C19orf54,TAF2,SEC61A1,WDR7,RPLP1,CBLN2,RBMS1,FUS,GEN1,LRP8,COIL,LRCH1,GALK1,ZNF786,RPS2,SESTD1,TRAK1,JMJD6,SIKE1,AKT1S1,KRI1,FBXO3,ERH,GATC,NDUFB4,PPP1R8,PRDM4,GTSE1,GEMIN6,DCP1A,SGCB,S100A6,IMPA2,NUDC,PDPK1,TK1,GUK1,TNFAIP3,GALC,ZNF512,KIAA0930,MRPS10,DDX39A,RPA1,ZNF862,ZNF180,KEAP1,POLE,TATDN2,PITX1,CAPN7,LRPPRC,PML,HMGB2,USF2,ANAPC4,SRM,DDX47,MCCC1,CDC42SE2,S1PR2,CDIPT,SEC16A,SSR1,LIN9,PCNA,ZNF639,TRMU,PIK3R2,ETV6,TXLNA,PPCDC,FAM86C1,MYBL1,MRPL32,CCAR1,ABCC5,PBXIP1,BAZ2A,TLK1,MRPL12,EZR,LNX2,LRP5,BRCA1,PRKRA,STX16,EPB41,OPTN,SEPT1,SOCS4,QRSL1,PIEZO1,OSGEPL1,GLCCI1,NUDT11,NAA60,GEMIN7,SEPHS2,LZTR1,RACGAP1,PPP3CB,B4GALT4,RLF,RAPGEF6,SNRNP25,RB1,VASP,MED8,VMP1,PPIL2,MEA1,TIMELESS,AHDC1,ALDH18A1,TMEM8A,ABCC1,PREB,TRAPPC9,AACS,MEMO1,KRAS,RTF1,UBE4B,NFATC2IP,LY6E,ARPC1A,ZNF174,PSMC4,GOLGA4,PALB2,SYNCRIP,PRPS2,NIPA1,TIGD2,RNF114,FOXM1,MRPL39,XAB2,SUMO2,DUSP22,COMMD8,RPL11,CSDE1,MDM2,CORO1A,MINPP1,METTL9,POC5,DVL2,GM2A,PSMA8,COQ10B,CPOX,TIGD5,SLC26A6,CYP20A1,PRPF3,TXNL4A,RPSA,SRSF1,DNAJC10,SCAP,ZNF700,PLEKHG4B,TIMM17A,TOMM6,FAU,LTA4H,AP2S1,USP53,INTS2,CTDP1,MIF4GD,CDT1,ARID5A,SUMF1,GGA2,AP3S1,CSNK1A1,RMI1,TFRC,PTPN2,STARD9,IRF4,GSTK1,NDUFV1,SLC1A4,CWC27,SLC35B4,DDX31,ABCD1,RPAP3,CNTN5,SNX2,ZMYM5,CCDC34,CHCHD6,BSDC1,KPNA4,CDKN2AIPNL,FBXO41,BIRC5,TFE3,SNAP29,CDCA7L,PKD2,ACADM,CHMP7,SAT2,GCSH,ZNF496,TMEM109,TAP1,YTHDF3,NHLRC3,IKBIP,EIF1B,ELMOD2,KIFC1,DBNDD1,CYB5RL,PARPBP,RNASEK,CDC25B,PRADC1,DNMT1,NOL12,ORAI2,USO1,AKT2,NOL8,GNG7,AURKB,MCFD2,SLC25A5,ZFAND5,MAK16,STT3A,TMED10,PSMD8,EIF2D,ITGB1,PTPN7,UQCRH,RRS1,ARRB2,RTN3,ZNF598,DDX58,WSB2,PPIB,MUT,GMFG,HLA-E,NDUFA4,MAN2B1,METTL3,CFLAR,NDUFS4,RNF121,MEX3C,KLF16,HDAC7,DAD1,BDH1,PCYT2,GNAI2,ANKHD1,TERF2,MORC3,KCTD20,SEPT8,DCTD,PKM,TOMM40,PATL1,ADSS,SERTAD2,SERF2,ZFP92,NSF,DCK,ERGIC3,ACLY,LPCAT4,VCPIP1,YY1,PPP6R2,MAP3K5,PPP6R3,RNF14,CDK2,ZC3HAV1,SYS1,ZBTB37,URB2,EIF3D,MAGED1,KLHL18,ADPGK,SLC25A44,AP1B1,SDHA,PAIP2,PHC2,CRKL,TERF2IP,MOAP1,CYHR1,ZNF75D,SHC1,UCHL5,NAA35,TMBIM1,CCT2,CDKN2AIP,MKLN1,HMGN4,LYRM1,GALK2,CDC23,SHCBP1,AP4E1,PRDM11,VEZF1,PPP2R5A,ACYP1,STAT1,PPA2,TRIM32,RHEBL1,R3HCC1L,C1orf112,TCF3,MRI1,BRAP,AGPAT3,MYNN,SDF2L1,SPR,RAB11A,REEP5,FOXO3,MAD2L2,CCDC28A,PIP5K1C,RBM17,MAT2B,PTEN,CENPJ,TAGLN2,OSTC,CREB1,PACS2,NCOA2,SMC4,RNASEH2C,NEK7,NET1,PARP4,TBRG4,ANAPC2,RPL27A,YIF1A,SGSH,HGS,TTLL4,SLC38A7,MFAP1,CCDC69,BRWD3,ESYT2,SKA3,NPHP4,UBE2E2,HNRNPAB,PLXNC1,ST13,TMEM184B,DNAJC24,ZNF107,KIF2C,SLC29A1,AGFG1,SIRT2,FKBP2,USP48,UBQLN2,SNRPD3,CUTC,EDC3,UBLCP1,ZNF804A,RAP1A,THADA,EIF4A3,AP3S2,ATG3,DPYSL2,PPP1R12C,AKR1B1,NDUFB9,JOSD1,RP2,TTC4,TECR,ARID4A,FGFR1OP2,TIMM50,TDP1,DPM1,FOPNL,SLC16A7,WDR82,SLC25A22,STK17B,DHX15,CHAF1A,GEMIN5,COPS6,SASS6,RPS26,PSMC1,SLC12A7,TBC1D12,TM9SF4,ZNF768,UFC1,MED13L,TIA1,MEF2A,EPHX2,PITHD1,RHBDD1,NFATC3,BANF1,ZNF335,BUD31,YBX1,KNTC1,ACAD8,UBE3C,ZNF189,ALDH9A1,KDELR1,TSTA3,CIC,OXR1,PSMA1,SEPT7,NAP1L1,ODF2,EXOC4,KIAA1328,NUP62,PITPNA,NAA20,PTDSS1,MZT2B,PDSS2,C7orf26,TMEM106C,IMMT,ASH1L,CHERP,WDYHV1,PLAGL2,CHKB,IRF3,TWF2,PAIP1,ANKRD28,ANKLE1,FARSA,SAR1A,SCAMP4,APOOL,PDIA6,ACSL5,TOR1AIP2,AZI2,GFER,RAD54B,DAP3,TMEM41A,ZNF317,GADD45B,AKNA,REEP4,CBX4,MIF,KIF3B,GOLPH3L,SH2D3A,CASP6,TOR3A,SRGN,DBF4,MFSD10,SAC3D1,CTNNBL1,YIF1B,CLDND1,TTC17,SLC25A1,GINS1,PAQR6,CSNK1G2,TELO2,ADAM17,HMGN1,NASP,ASPM,PPP1R21,PRKAR1B,SYMPK,TARS,SNRPA,MAPK3,HSPA1B,HLA-B,ATAD2,PLAA,ZNF330,OSBPL8,KBTBD7,PREPL |
| 3.580e-08 | -17.15 | cellular respiration | biological process | GO:0045333 | 152 | 50 | 17256 | 2622 |
COX15,COX5B,NDUFA5,NDUFV2,NDUFS1,SUCLG1,NDUFB6,NDUFAF2,UQCR10,MECP2,MDH2,SLC25A12,NDUFA4,COX4I1,CYCS,SDHA,NDUFS7,NDUFS4,FASTKD3,MTFR1L,NDUFV1,NDUFA2,NDUFB4,CS,SUCLG2,NDUFB9,NDUFS8,CYC1,NDUFA3,COQ10B,IDH3A,MTFR2,TBRG4,ADSL,OGDH,NDUFA7,NDUFB1,TAZ,POLG2,CAT,SDHB,COX7A2L,NDUFA11,COX8A,DHTKD1,COX5A,MDH1,UQCRH,NDUFS5,IDH3B |
| 3.582e-08 | -17.14 | YWHAQ (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta) | protein interactions | 10971 | 466 | 121 | 17029 | 2761 |
WASF2,CYLD,TSC2,RPLP2,RAF1,MYH9,CSNK2A1,RCOR3,SDHA,PARK7,BCAP31,PABPC4,EDC3,PRNP,HNRNPA2B1,MDM2,EIF4A3,PIK3R2,MRPS27,CDKN1B,CRY2,CDC25B,TP53BP2,EIF5,DNMT1,CCAR1,CFL1,SRSF10,CDC37,CDC5L,UBQLN4,CUL3,HNRNPF,UBE2V1,NFATC2,BRCA1,MEF2D,MCFD2,MCM2,TRIM28,GIGYF1,CHAF1A,SRSF1,OPTN,EPB41,AFDN,IARS2,H2AFX,ACTB,TRIM32,FUS,PTPDC1,NCOA1,PDXK,ARRB2,SMURF1,MYL12B,CBX4,CAPN1,TUBB,SRSF6,RAE1,DHX9,RPL15,CBLL1,KIF23,AKT1S1,ATP5F1B,CDK11B,SPR,CSNK1A1,FOXO3,CDC73,LMNA,WWP2,MAT2B,DTL,KIF5B,VASP,CBWD2,ZNRF2,HDAC7,DAPK1,CTPS1,ARHGEF2,RPL19,AHCY,MTX2,LUC7L2,LDHB,PDPK1,SAMD4B,STAU1,TNFAIP3,PRKDC,KIAA0930,USP42,LDHA,PKM,PDE3B,MARK2,PRDX1,TFEB,TPD52L2,TSC1,PDCD6,PCM1,UPF1,E2F1,CABIN1,YWHAZ,RUVBL2,ATP5F1A,SRSF3,MAP3K5,WDR62,NDE1,CDK2,ARHGAP23,YWHAH,FAM83G |
| 3.583e-08 | -17.14 | ribonucleotide binding | molecular function | GO:0032553 | 1855 | 367 | 17224 | 2647 |
RAB14,ABCC10,TAP1,DHX8,GLUD1,UBE2I,EEF2K,KIFC1,CDK5,NEK6,RAB4A,ATP13A3,PDS5B,DNM2,UPRT,SUCLG2,MAST2,PLK3,RHOBTB3,NRAS,AKT2,PBK,KIF15,MKI67,DDX20,SMC2,AURKB,MCM2,RFC2,RAB22A,RAB2B,ARF4,MAP3K4,MKNK1,KIF18B,LIMK1,MYO18A,RNASEL,LONP2,PFKP,DDX42,DDX58,HSPH1,RECQL,CHTF18,RHOC,TRIO,GSPT2,PRKAA1,DHX9,RRM1,RAB23,CERK,KIF23,TOP2B,EIF2AK4,RTKN,DDX56,SMC3,MCM5,EFTUD2,CTPS1,MSH2,DAPK1,RTCB,PIKFYVE,GNAI2,PHKG2,UBE2QL1,CARS2,DDX28,COQ8A,MAPKAPK3,DHX29,NOA1,PGS1,TYW1,GTPBP4,PIP4K2C,SEPT8,RIT1,PKM,ABCF1,MAP2K2,CCT8,RHOB,PI4K2A,XRCC5,ADSS,EPRS,NSF,CSK,CSNK1G1,DCK,QARS,ACLY,MAP3K5,CDK2,NRBP1,ACSF2,RHOG,KARS,ABCA3,TP53RK,RAB11B,RPS6KA1,RAF1,CHD1L,KIAA0232,ACTR3,RAC1,OLA1,TPX2,MYH9,EFL1,PRKACA,CBWD5,FLAD1,RAB21,PRKD3,ATP2A2,RALB,UBA5,ADCY9,CLCN6,SEPT11,TAP2,AQR,ARL5A,CDK12,ADCY7,CCT2,ULK3,ATP13A1,MAP4K4,TAOK1,PFKFB3,GALK2,PKMYT1,DNAJA1,RAB1A,MAT2A,DHX57,DDX17,KIF2A,RAD51C,HSPA4,JAK1,RAB24,GUCY1B1,HIPK2,CBWD1,PDXK,PPP5C,CSNK1D,TUBB,DYNC1LI2,RHEBL1,PRPF4B,POLQ,GALK1,ANXA6,TWNK,IP6K2,ATP5F1B,BLM,PMVK,IFT27,RAB11A,PIP5K1C,SRXN1,GATC,CBWD2,ARF5,TTLL12,MAP3K14,UBE2M,MSH6,SMC4,PDPK1,TK1,DDX24,GUK1,NEK7,BMS1,RHOT1,DDX39A,GUF1,KIF11,MARK2,MYO1F,GNA12,KIF18A,TTLL4,MAPK6,ASNA1,DDX5,DDX52,DDX47,UBE2E2,YTHDC2,MCCC1,CSNK2A1,UBE2Q1,UBE2Z,ABCB10,KIF2C,MAPK14,PAPOLA,ABL2,RAB8A,RAP1A,CDC42,EIF4A3,RAB35,TRMU,XRCC2,KIF22,RP2,EIF5,ABCC5,SRPK2,PLK1,LARS,SNRNP200,SEPT9,HARS,TLK1,CDC6,RAB5B,LSG1,STK17B,DHX15,RHEB,SEPT1,CHD3,IARS2,BAZ1B,QRSL1,ACTB,STK11,CHEK2,VPS4A,ROCK1,PSMC1,SEPHS2,UBE2D3,CDK13,THRAP3,RAB6A,CHKA,UBE2Q2,KIF13B,ALDH18A1,N4BP2,CSNK1G3,ABCC1,NTPCR,AACS,ACSL3,KRAS,MAP4K3,EIF2AK1,UBE4B,SEPT7,DAPK3,BBS12,MASTL,PSMC4,GNAS,PRPS2,NLRC5,RUVBL2,ATP5F1A,MYO9A,EHD4,UGP2,PMS2,UCK2,SMARCA4,RRAGC,UCK1,CHKB,ORC1,ATP6V1B2,LYN,TWF2,CHD1,MIEF1,FARSA,PDK2,IARS,SAR1A,NVL,KIF14,SCYL3,ACSL5,CLCN3,CGAS,RAB7A,ARL5B,RAD54B,DAP3,ATP1A1,IDE,DHX16,CLK3,STK38,FASTK,XRCC3,MAPK1,ABCA1,RAD51D,KIF3B,NADSYN1,SHPRH,TOR3A,GNE,SCYL1,SMC6,ARFIP2,ARF1,MYO9B,CDK11B,CSNK1A1,SCYL2,PIP4K2A,GFM2,WRNIP1,KIF5B,GTPBP3,STARD9,FGFR3,NDUFV1,GART,GRK2,ABCD1,DDX31,CAMK2G,MYO5A,CSNK1G2,RHOA,PRKDC,HELB,BTAF1,ATP2C1,ABCF2,TUFM,PRKAR1B,NADK2,PNPLA8,RHOT2,CDK11A,TARS,MAPK3,DDX23,HSPA1B,MFN2,RAB18,NEK1,UPF1,ATAD2,UBE2C,RPS6KC1,HRAS,HIPK3,TYW1B |
| 3.613e-08 | -17.14 | The citric acid (TCA) cycle and respiratory electron transport | REACTOME pathways | R-HSA-1428517 | 158 | 54 | 10287 | 1696 |
COX5B,NDUFA5,NDUFV2,NDUFS1,NDUFB6,SUCLG1,NDUFAF2,UQCR10,MDH2,NDUFA4,COX4I1,CYCS,ATP5F1B,ATP5PF,SDHA,NDUFS7,NDUFS4,NDUFAF6,PDK2,NDUFV1,NDUFA2,NDUFB4,CS,SUCLG2,NDUFB9,NDUFS8,CYC1,NDUFA3,LDHB,TIMMDC1,COQ10B,IDH3A,TMEM126B,LDHA,GLO1,NDUFA7,OGDH,ATP5MF,NDUFB1,HAGH,PDHX,MPC1,SDHB,ATP5MC3,NDUFA11,COX7A2L,LRPPRC,COX8A,SLC16A1,COX5A,UQCRH,NDUFS5,ATP5F1A,IDH3B |
| 3.628e-08 | -17.13 | XRCC6 (X-ray repair cross complementing 6) | protein interactions | 2547 | 296 | 85 | 17029 | 2761 |
COX15,ATXN3,ST13,PHRF1,SUMO2,CHD1L,PTTG1,CSNK2A1,ATP6V1B2,SDHA,CMTM6,ANKRD28,TERF2IP,CSDE1,VAV1,USF1,MDM2,PCNA,PIN1,DNM2,CRY2,TARDBP,ADCY7,CCDC57,EID1,NFATC2,BRCA1,VDAC1,MCM2,RPSA,CENPU,CHAF1A,SUPT16H,DPYSL3,TONSL,RPLP1,UHRF2,PLGRKT,H2AFX,QRSL1,CLU,H3F3A,ARRB2,SMURF1,XRCC4,COIL,POT1,SSRP1,DHX9,TKT,KIF23,RGS2,CSNK1A1,LMNA,CFLAR,RPA2,GART,AHSA1,MSH2,H2AFY,ORC3,TNRC18,MSH6,TERF2,PDPK1,KAT2A,PRKDC,ILF3,RPS10,ISG15,RPA1,CBX3,CAND1,XRCC5,PAXX,BIRC5,CDCA5,ARAP1,IMPDH1,YWHAZ,WDR76,YY1,RBBP4,CDK2,PGAM1 |
| 3.681e-08 | -17.12 | GROSS_HYPOXIA_VIA_HIF1A_UP | MSigDB lists | GROSS_HYPOXIA_VIA_HIF1A_UP | 75 | 31 | 17377 | 2626 |
ACSL5,SRM,AMPD2,LZTR1,NOP2,ACSL3,AMD1,USP42,MOGS,RRM2,UBE4B,PLXNA1,SRSF5,CDC23,BZW2,WRB,TFRC,MAT2A,SRSF1,SLC19A1,NAP1L1,GART,SLC1A4,EXOSC1,AKAP8,KPNA2,TARDBP,SCAMP4,F2R,HRAS,NUDT3 |
| 3.696e-08 | -17.11 | MARTINEZ_RB1_TARGETS_UP | MSigDB lists | MARTINEZ_RB1_TARGETS_UP | 641 | 148 | 17377 | 2626 |
HNRNPAB,ADD1,AGPAT1,CCNL2,MIS12,UBLCP1,SF3B2,PAPOLA,USF1,IL6ST,DNM2,TCEA1,TECR,MOB1A,DRAM2,ABCC5,USP34,PLK1,AATF,PBK,MKI67,SREK1,PITPNB,SOX4,KRTCAP2,RAB2B,CLNS1A,EIF3A,DPYSL3,BRD2,TPP2,ACTB,ST3GAL2,SMAD1,CHPT1,UBE2D3,RECQL,HJURP,SCOC,PHB2,NKD2,RRM1,MEF2A,RACGAP1,MAN2B1,THRAP3,RAB6A,DNAJB1,EPHX2,VPS25,SPAG5,WDR48,C4orf3,CTR9,NSUN4,SIGMAR1,ZMYND11,AMD1,ZNF574,SEPT8,ITM2A,KRAS,PLEC,EIF4H,SF3A2,RDH11,GNAS,PTPRF,CAT,PFDN5,NAP1L1,GOLGA4,PCM1,NSF,CEBPG,RBBP4,MAP3K5,RNF14,PDLIM5,MRPL3,RNF114,RHOG,TCF12,NDUFA5,IMMT,MRPL39,ANK3,UCK1,SMARCA4,NIT2,SAFB2,BCAP31,APP,PRKD3,APLP2,STRBP,SAR1A,SIAH1,INTS12,RPN2,LMAN1,ATF2,ARL5A,CTDSP2,ACSL5,CLCN3,UBQLN4,CCT2,KAT7,TAOK1,PFKFB3,GLO1,SERP1,ERC1,IDE,JAK1,HIPK2,DNAJC17,RBMS1,SNRPG,ZNF445,MIF4GD,CASP6,PDAP1,TUBGCP2,TFRC,TMCC3,ADD3,NDUFA2,ZNF260,NDUFA3,PDPK1,PPP3CA,PRKAR1B,TUFM,ILF3,KIF11,ZFR,RPA1,GNA12,TWSG1,ACOX1,TFDP1,STX18,CTBS,ASNA1,PSAP,HIPK3 |
| 3.701e-08 | -17.11 | GSE24574_BCL6_LOW_TFH_VS_TCONV_CD4_TCELL_DN | MSigDB lists | GSE24574_BCL6_LOW_TFH_VS_TCONV_CD4_TCELL_DN | 193 | 59 | 17377 | 2626 |
MIF,SRM,GCLM,IMMT,TXN,CENPF,EBNA1BP2,SLC29A1,ORC1,FKBP2,BLM,PMVK,MRPL19,FANCI,BCAT2,EBP,KIFC1,RPA2,FANCL,HOMER1,BDH1,TXLNA,CORO1A,AHCYL1,UBE2M,NIPSNAP1,GINS1,PLK1,NRAS,HMGN4,RAD51AP1,CPOX,LDHA,MYBL2,HTATIP2,ADSL,AURKB,PITPNB,TOMM40,MCM2,PSMB9,SNRPA,PRDX1,MAT2A,FADD,CHAF1A,PRIM1,HMGN2,YIF1A,EPRS,SEC23IP,MTHFD2,PRPS2,DBI,NFIL3,COX8A,CDK2,AP2S1,ESPL1 |
| 3.725e-08 | -17.11 | SARRIO_EPITHELIAL_MESENCHYMAL_TRANSITION_UP | MSigDB lists | SARRIO_EPITHELIAL_MESENCHYMAL_TRANSITION_UP | 175 | 55 | 17377 | 2626 |
SKA3,UCK2,KIF23,SDF2L1,BLM,CCNB1,BRIX1,STMN1,SLC20A1,CRLF3,POLR3K,SRXN1,FBXO5,CALM2,DTL,PCNA,CCNA2,MCM5,FJX1,PRC1,MSH2,H2AFY,KNTC1,MYBL1,TACC3,PLK1,RFC3,ASPM,MKI67,RRM2,CDC6,NUP155,BRCA1,PKMYT1,MCM2,ANLN,RFC2,ODC1,KIF11,ASF1B,PRIM1,FBXO41,RBL1,DCK,ZNF367,CEP55,TFDP1,CDCA5,E2F1,H2AFX,RRS1,CDK2,YWHAH,ESPL1,TUBB |
| 3.725e-08 | -17.11 | GSE11386_NAIVE_VS_MEMORY_BCELL_UP | MSigDB lists | GSE11386_NAIVE_VS_MEMORY_BCELL_UP | 175 | 55 | 17377 | 2626 |
ADD1,POLR2K,RPS6KA1,CENPF,RBM8A,VPS45,RRM1,CDCA8,KIF23,COX4I1,NCAPG,POLR3K,SSR1,CALM2,DTL,LYAR,PSMD2,EFTUD2,PRC1,H2AFY,KIF22,KNTC1,PDIA6,CFL1,ELOF1,CDC37,CLPTM1,PPP3CA,ASPM,DHX29,RAD51AP1,IDH3A,ZMYND11,PBK,GOPC,KIF15,PSMB7,CCDC34,RRM2,CDCA2,GALK2,SMC2,MTX1,SHCBP1,LUC7L,APPL1,ECH1,GINS4,KIF18A,TOMM6,QARS,CEP55,CDK2,EGLN1,NXT2 |
| 3.725e-08 | -17.11 | GO_CONDENSED_CHROMOSOME | MSigDB lists | GO_CONDENSED_CHROMOSOME | 175 | 55 | 17377 | 2626 |
ZNF207,SKA3,NSMCE4A,HJURP,CENPF,SMC6,CTCF,NUF2,KIF2C,PMF1,BLM,CCNB1,UBE2I,CSNK1A1,NCAPG,MIS12,SPAG5,ADD3,SMC3,AHCTF1,AKAP8,BANF1,NUP107,H2AFY,KIFAP3,SS18L1,KNTC1,CENPM,NUP85,SEH1L,SMC4,PLK1,BRD4,MKI67,RANGAP1,AURKB,SMC2,BRCA1,SEPT7,PHF6,CBX3,RAD51C,DSN1,BIRC5,NSMCE2,CDCA5,H2AFX,LRPPRC,BAZ1B,HMGB2,CENPT,RRS1,NDE1,CDK2,XRCC4 |
| 3.725e-08 | -17.11 | GSE14000_4H_VS_16H_LPS_DC_DN | MSigDB lists | GSE14000_4H_VS_16H_LPS_DC_DN | 175 | 55 | 17377 | 2626 |
C9orf78,GLT8D1,KDM4A,C5orf30,RAB23,BTN3A1,NIT2,USP48,ZADH2,RCOR3,RSAD1,RRP36,EPM2A,TMCC3,SLC25A36,MOAP1,RPA2,SNUPN,KDM2A,SLC38A5,MTMR4,AP3S2,RBM34,GRSF1,ZDHHC13,TPST1,PDS5B,FBXW2,ORC3,MOB1A,RPAP3,TTPAL,DDX28,NXT1,POLR2D,RNPS1,DNAJC9,NFATC2IP,LRRC1,PEF1,BSDC1,SMAP2,SUPT16H,TMEM184C,TMEM41A,PDRG1,DHX16,NFIL3,PML,H2AFX,RUFY3,TRAF5,POT1,ZC3HC1,CCDC137 |
| 3.725e-08 | -17.11 | GSE17974_2.5H_VS_72H_IL4_AND_ANTI_IL12_ACT_CD4_TCELL_DN | MSigDB lists | GSE17974_2.5H_VS_72H_IL4_AND_ANTI_IL12_ACT_CD4_TCELL_DN | 175 | 55 | 17377 | 2626 |
INTS2,RECQL,CMAS,TXN,GOLPH3L,UGP2,ADD1,RPS6KA1,RHOC,CUTA,TMEM97,UCK2,LETMD1,RAB6A,PARN,STMN1,MAD2L2,ANKRD39,DLG5,CDK5,GSDMB,C4orf3,MTMR4,ARF5,SRI,NUP107,CS,CDC25B,TCEA1,MRPL48,C12orf75,NUP85,CAMK2G,S100A6,DRAM2,PTPN18,HMGN4,HPDL,NOA1,EIF2AK1,STYXL1,PRPSAP1,CLNS1A,STOML2,ALKBH6,RAD51C,NSF,NSMCE2,DBI,PTAR1,MPV17,CDK2,RHEBL1,POLQ,GEMIN7 |
| 3.742e-08 | -17.10 | GSE37301_COMMON_LYMPHOID_PROGENITOR_VS_PRO_BCELL_DN | MSigDB lists | GSE37301_COMMON_LYMPHOID_PROGENITOR_VS_PRO_BCELL_DN | 184 | 57 | 17377 | 2626 |
WSB2,EXOC3,COX5B,GGNBP2,MUT,TMEM41B,CDT1,SUMO2,YTHDC2,RRM1,CDK13,HAUS4,RAB6A,MXD4,STMN1,CRLF3,RCOR3,NDUFS4,FBXO5,NFATC3,ADD3,CCNA2,NVL,ARPC5,KIF14,CNN2,MRPL40,DNMT1,FDFT1,SRPK2,WDR41,CPNE1,GCC2,DENND4C,DENND1B,PIP4K2C,GLO1,MCM2,APPL1,ASF1B,RAD54B,CHAF1A,ANKZF1,MKNK1,SGSH,SMAD2,MAGT1,BIRC5,ELMO1,PML,ACTB,ZNF45,MRPL13,RTN3,AP2S1,MYL12B,NXT2 |
| 3.822e-08 | -17.08 | GO_MACROMOLECULAR_COMPLEX_BINDING | MSigDB lists | GO_MACROMOLECULAR_COMPLEX_BINDING | 1327 | 271 | 17377 | 2626 |
MAX,H2AFZ,ADD1,ADAM10,KIFC1,DNM2,AP2B1,NUP153,MAST2,SMARCE1,DNMT1,SRP72,NRAS,GABPA,KIF15,KRIT1,HHEX,SMAD2,BRD2,RAD18,KIF18B,TMED10,MAP4,MYO18A,ITGB1,RNASEL,ARRB2,NMD3,PFKP,HDAC2,ANXA11,SSRP1,PPIB,MAPRE1,GMFG,CLSPN,MUM1,PRKAA1,STRN4,KIF23,NDUFA4,TOP2B,EZH1,CDC73,CFLAR,FKBP1A,SMC3,ARPC5,HDAC7,MCM5,ZNF326,MSH2,RNF135,GNAI2,TNRC18,TERF2,EIF5A,CYFIP1,DHX29,MTA2,ZMYND11,ARID1A,ADRB2,ELK1,EIF4H,ABCF1,PHF6,AKAP1,HMGN2,XRCC5,PI4K2A,FAS,PTPRF,FNTA,GOLGA2,NSF,RBMX,FAM83D,CABIN1,NDE1,CDK2,ZNF207,DNMT3A,SUZ12,ACTR3,OLA1,MYH9,PRKACA,GNB2,SHC1,UCHL5,MTA1,CDKN1B,ATF2,RPRD1B,RNF169,PSRC1,BRD4,MAPRE2,HMGN4,WBP2,ELP4,NUSAP1,PSMB9,TRIM28,TAF2,KIF2A,EIF3K,SEC61A1,SAFB,CORO1C,PPP5C,LRP8,TUBB,USP13,ADAM23,POLQ,ANXA6,MECP2,SECISBP2,RAB11A,FOXO3,HLA-A,NEIL2,JAKMIP1,PTEN,PTPN11,PRC1,CITED2,NCOA2,MSH6,SPTAN1,PDPK1,KAT2A,MACF1,KIF11,FADD,GNA12,KIF18A,POLE,LTBP4,LRPPRC,CD81,IGBP1,CPEB2,ST13,SIRT2,KIF2C,S1PR2,MAP1LC3B,GIT2,PRNP,ABL2,DST,PCNA,RAP1A,SYNM,EIF4A3,DPYSL2,RCSD1,NOC2L,KIF22,MCMBP,OGG1,TIMM50,SP3,PLK1,RBX1,GMFB,PSMG1,EZR,WDR82,PBRM1,BRCA1,CHAF1A,PAF1,PQBP1,ADAM9,BAZ1B,ACTB,BEND6,DNAJB2,CENPF,CTCF,MEF2A,RACGAP1,NCKAP1,TTF1,MBD2,KIF13B,CTR9,ATP6V0D1,HP1BP3,CIC,LDB1,CAMSAP1,KRAS,EIF2A,ICAM2,ARPC1A,GNAS,CDCA5,PRMT7,NUP62,RUVBL2,RBBP4,APOL2,SMARCD1,WASF2,MBD1,ASH1L,PMS2,SMARCA4,ORC1,LYN,RPAIN,BCAP31,NVL,KIF14,RPN2,CORO1A,ABI1,TIMP2,TUBGCP5,WIPF1,NFATC2,VDAC1,MBD3,TMEM201,RPSA,SCAP,TULP3,SCARB1,NCOA1,H3F3A,REEP4,SMURF1,SMAD4,CBX4,SLC30A9,KIF3B,DNAJC2,RAE1,SRGN,LETMD1,HMGN3,MYO9B,TUBGCP2,FERMT3,KIF5B,PTPN2,STARD9,CTSS,ARHGEF2,H2AFY,STAT3,TELO2,PPP1R9B,HMGN1,ADAM17,NASP,HMGN5,SNX2,WDR81,MEN1,UPF1,ATAD2,BIRC5,MBD6,RBPJ,TERF1 |
| 3.823e-08 | -17.08 | GNF2_RRM2 | MSigDB lists | GNF2_RRM2 | 40 | 21 | 17377 | 2626 |
PLK1,FOXM1,ASPM,CENPF,MKI67,RRM1,CDCA8,RRM2,NUSAP1,AURKB,MCM2,KIF11,CCNA2,PCNA,KIF18B,BIRC5,H2AFX,CENPM,CCNB2,UBE2C,ESPL1 |
| 3.825e-08 | -17.08 | GO_MICROTUBULE_BASED_PROCESS | MSigDB lists | GO_MICROTUBULE_BASED_PROCESS | 478 | 117 | 17377 | 2626 |
ZNF207,FGFR1OP,ATXN3,DYNLL1,ACTR3,XIAP,AP3M2,TPX2,MYH9,KIF2C,CNTROB,CCNB1,STMN1,BIRC2,KTN1,APP,KIFC1,DST,RAB21,NEK6,CDC42,AP3S2,KIF14,DNAAF2,XRCC2,AP2B1,KIF22,CEP63,RNF19A,DNAL4,TACC3,DCTN1,PLK3,PLK1,PSRC1,BIRC3,FOPNL,TUBGCP5,KIF15,EZR,NUSAP1,AURKB,BRCA1,BICD2,RAB1A,EML4,TMEM201,KIF2A,KIF18B,CHD3,AXIN1,E2F4,MAP4,CHEK2,VPS4A,DVL1,CLN3,SASS6,AP2S1,CSNK1D,DYNC1LI2,TUBB,KIF3B,PPP1R12A,EYA1,DCTN2,CIB1,KIF23,KLC1,RACGAP1,HAUS4,RAB6A,AP3S1,IFT27,RAB11A,HAUS2,TUBGCP2,SPAG5,LMNA,FBXO5,KIF5B,STARD9,SMC3,CCP110,CENPJ,KIF13B,PRC1,GTSE1,ARHGEF2,KIFAP3,IFT46,GCC2,RHOA,TACC1,ASPM,NEK7,MYBL2,MAP7D1,WDR81,RHOT1,RHOT2,KIF11,BBS12,HAUS8,KIF18A,PCM1,GOLGA2,BIRC5,LRPPRC,SLC16A1,PKD2,SSNA1,NDE1,WDR62,CDK2,ESPL1,SNAPIN |
| 3.840e-08 | -17.08 | LINDGREN_BLADDER_CANCER_CLUSTER_1_DN | MSigDB lists | LINDGREN_BLADDER_CANCER_CLUSTER_1_DN | 356 | 93 | 17377 | 2626 |
IER2,H2AFZ,POC1A,TRIM11,PTTG1,UCK2,TMEM97,SMARCA4,KIF2C,ORC1,AP1B1,CCNB1,STMN1,TCF19,SSR1,BCAT2,KIFC1,CDKN2C,KIF14,POP7,CDC25B,RNASEH2A,TACC3,PLK1,PSRC1,RFC3,TIMP2,BIRC3,SLC26A6,RRM2,WDHD1,CDC6,CDCA2,BRCA1,SLC17A5,VDAC1,CDCA4,RBL1,ST3GAL2,KPNA2,CLN3,ARRB2,SMURF1,DEPDC1,ANXA6,CASP6,CDT1,CENPF,CDCA8,DLGAP4,KIF23,RACGAP1,PDXDC1,TFRC,FERMT3,EBP,PDXP,CLIC4,CTNNBL1,MCM5,PRC1,GTSE1,H2AFY,TAGLN2,MAP3K14,SLC12A2,CAMK2G,AMPD2,ZDHHC18,TK1,ABCF2,MYBL2,ILF3,PSMA1,KIF11,PATL1,NEU1,ARHGAP15,SH3BP5,MTHFD2,ATAD2,POLE,BIRC5,DBI,E2F1,FAM83D,NUP62,HMGB2,CTSA,RGL1,CCNB2,UBE2C,ACSF2 |
| 3.842e-08 | -17.07 | Influenza Life Cycle | REACTOME pathways | R-HSA-168255 | 146 | 51 | 10287 | 1696 |
RPS15,NDC1,RPS2,NUP188,RPLP2,POLR2K,RAE1,NUP54,RPL15,NUP205,GTF2F1,RPL11,RPL23A,NUP210,RPL17,GRSF1,NUP107,NUP153,RPL19,NUP85,RPL22L1,SEH1L,RPL29,RPL35,POLR2I,POLR2L,POLR2G,RPL8,RPL38,POLR2D,RPL6,RPS10,RPS24,NUP155,RPL27A,RPS9,POLR2A,RPSA,RPL36,RPL37,KPNA1,POLR2J,RPL32,RPS27A,RPS14,RPLP1,NUP62,FAU,RPS26,NUP58,AAAS |
| 3.877e-08 | -17.07 | regulation of ubiquitin-dependent protein catabolic process | biological process | GO:2000058 | 148 | 49 | 17256 | 2622 |
USP7,SUMO2,UBXN1,NKD2,SIRT2,UBQLN2,CSNK1A1,PSEN1,BCAP31,ANKIB1,PARK7,FBXO22,DDRGK1,USP5,RAD23A,RPL11,MDM2,PTEN,DDA1,RAD23B,RNF19A,SENP1,PDCL3,SOCS5,RYBP,PLK1,PLK3,UBQLN4,LONRF3,RBX1,PBK,GBA,HSPA1B,GNA12,KEAP1,HSPBP1,HIPK2,AXIN1,SOCS4,OGT,PML,CLU,DVL1,SMURF1,RNF14,RNF139,CSNK1D,SVIP,RNF114 |
| 3.928e-08 | -17.05 | RBBP6 (RB binding protein 6, ubiquitin ligase) | protein interactions | 5930 | 78 | 33 | 17029 | 2761 |
NIFK,MZT1,EWSR1,KMT2E,GSPT2,VAV2,CUL1,UBE2I,ETS1,RBM4,MAD2L2,RB1,MDM2,PCNA,NEK6,ATIC,RBM34,FBXO7,YBX1,NDUFB9,CPSF4,SRPK2,DDX24,SNRPB,CAPZA2,LUC7L,RCC1L,HSPA4,CLK3,RPS14,NCOA1,PPP5C,CD81 |
| 3.975e-08 | -17.04 | PPM1G (protein phosphatase, Mg2+/Mn2+ dependent 1G) | protein interactions | 5496 | 108 | 41 | 17029 | 2761 |
USP7,HSPH1,EWSR1,COPA,UGP2,RPS6KA1,COPE,JMJD6,PAWR,XPO7,SPR,STMN1,MAPK14,STAM,RBM4,PAIP1,COPB2,LMNA,SRXN1,WWP2,TERF2IP,AHSA1,TTC9C,AHCYL1,TERF2,SRPK2,PPAN,PSMA1,USP36,IRF5,TFEB,CAND1,TPD52L2,HSPA4,PFDN4,STAT6,H2AFX,UBE2C,TERF1,FAF1,VPS29 |
| 3.984e-08 | -17.04 | FRASOR_RESPONSE_TO_SERM_OR_FULVESTRANT_DN | MSigDB lists | FRASOR_RESPONSE_TO_SERM_OR_FULVESTRANT_DN | 50 | 24 | 17377 | 2626 |
POLA2,TK1,FOXM1,CENPF,RRM1,KIF2C,MCM2,BLM,RFC2,STMN1,KIF11,CHAF1A,PRIM1,CDKN2C,CCNA2,POLE,TTLL4,MCM5,H2AFX,E2F1,TIMELESS,CDC25B,RNASEH2A,UBE2C |
| 4.000e-08 | -17.03 | GO_POSITIVE_REGULATION_OF_CELL_CYCLE_PROCESS | MSigDB lists | GO_POSITIVE_REGULATION_OF_CELL_CYCLE_PROCESS | 235 | 68 | 17377 | 2626 |
UBE2E2,SIRT2,ORC1,CCNB1,BECN1,PRKACA,APP,MDM2,PCNA,CDC42,KIF14,CDKN1B,CDC25B,CARM1,PLK1,PLK3,BRD4,BTG2,CUL3,LRP5,CDC6,NUSAP1,AURKB,BRCA1,SOX4,RAB1A,RAD51C,RPS27A,E2F4,NSMCE2,UHRF2,XRCC3,CHEK2,TFDP2,GEN1,KIF3B,PKP4,PHB2,GORASP1,KIF23,RACGAP1,CRLF3,RAB11A,CNOT3,FBXO5,RB1,PTEN,CENPJ,H2AFY,GTSE1,CNOT6L,TGFB1,RHOA,RBM38,GOLGA2,BIRC5,CDCA5,TFDP1,E2F1,FAM83D,PML,CNOT6,PKD2,UBE2C,CDK2,TERF1,ESPL1,CDKN2A |
| 4.005e-08 | -17.03 | GSE27896_HDAC6_KO_VS_WT_TREG_UP | MSigDB lists | GSE27896_HDAC6_KO_VS_WT_TREG_UP | 162 | 52 | 17377 | 2626 |
OTUD5,ZBTB10,ABCA3,MAX,ST13,IVNS1ABP,SLC41A1,AGFG1,XPO7,ZADH2,IL21R,GIT2,ARID1B,XPR1,PAPOLA,VAV1,APLP2,HOMER1,MEX3C,KIF13B,FOXN2,ARHGEF2,SS18L1,TTC17,CREB1,ABI1,PPP6R1,NSUN4,RNF169,LDHB,ADCY7,TSHZ1,SNX25,ARHGAP17,ETV3,GABPA,COG1,PLEC,IL12RB1,USP36,SLCO4A1,DAP3,GOLGA4,BRD2,SAFB,UHRF2,NCOA1,MYO9A,EYA2,PFKP,ESYT2,LRCH1 |
| 4.008e-08 | -17.03 | organelle localization | biological process | GO:0051640 | 596 | 140 | 17256 | 2622 |
FGFR1OP,PDCD6IP,NPHP4,AP3M2,KIF2C,CCNB1,SEC16A,BECN1,MIS12,KIFC1,CDK5,RAB8A,CDC42,AP3S2,DNM2,KIF22,TFG,SEH1L,PLK1,USO1,TMEM216,EZR,ESYT1,MCFD2,STX16,HHEX,TMED10,MAP4,STK11,VPS4A,RRS1,CLN3,NMD3,STARD3NL,RPS15,DNAJC5,MAPRE1,GORASP1,CENPF,KIF23,MEF2A,HAUS4,RAB6A,PSEN1,HAUS2,COPG2,SPAG5,CD59,CCP110,RIMS3,KIFAP3,MCPH1,PPP6R1,SYTL3,TMED2,PREB,TRAPPC9,HAUS8,SEC31A,PCM1,GOLGA2,NSF,SNAP23,CDCA5,ODF2,FAM83D,EXOC4,NUP62,YWHAZ,NDE1,PPP6R3,UNC13C,CHMP2A,RAB11B,DYNLL1,ACTR3,MYH9,NUF2,LYN,PRKACA,ANKRD28,ANKLE1,KIF14,PPP6C,CEP63,LMAN1,DCTN1,PSRC1,INTS13,CUL3,NUSAP1,BICD2,CDC23,CHMP2B,RAB1A,PEF1,TMEM201,CHMP4A,CEP55,CHMP4B,DYNC1LI2,TUBB,CSNK1D,KIF3B,DCTN2,CDT1,CDCA8,VPS45,TRAK1,SPDL1,AP3S1,RAB11A,SAPCD2,PIP5K1C,KIF5B,PDCD10,CENPJ,SEC24C,ARHGEF2,MYO5A,KAT2A,ASPM,SCFD2,RAB3IP,RHOT1,RHOT2,MARK2,MFN2,LEMD2,PDCD6,KIF18A,SEC23IP,SNAP29,LRPPRC,SSNA1,CHMP7,TERF1,ESPL1,ESYT2,SNAPIN |
| 4.052e-08 | -17.02 | GROSS_HYPOXIA_VIA_ELK3_UP | MSigDB lists | GROSS_HYPOXIA_VIA_ELK3_UP | 198 | 60 | 17377 | 2626 |
POLA2,MUM1,RACGAP1,CREBL2,PLXNA1,CCNB1,STMN1,MAPK14,WRB,TFRC,SPAG5,SAC3D1,RPA2,CDKN2C,GART,CCNA2,SSBP3,AKAP8,ARL6IP1,EI24,FAM89B,TARDBP,RBM3,MINPP1,SLC12A2,F2R,LPCAT1,SRSF10,TIMP2,SIGMAR1,AACS,PBK,AMD1,RRM2,WBP1,SRSF5,PLEC,CDC23,CBFB,MAT2A,SRSF1,FAS,NAP1L1,BIRC5,PDRG1,CORO1C,DBI,CDCA5,H2AFX,KPNA2,EHD4,NDE1,CD81,PGAM1,CCNB2,UBE2C,HRAS,ZMAT3,PDCD4,EGLN1 |
| 4.128e-08 | -17.00 | nucleoside phosphate metabolic process | biological process | GO:0006753 | 502 | 122 | 17256 | 2622 |
COX15,KARS,NDUFA5,PPCS,SUCLG1,NDUFB6,UQCR10,MDH2,UCK2,OLA1,UCK1,SLC35B2,EFL1,ADPGK,ATP6V1B2,ATP5PF,SDHA,PARK7,MBD4,FLAD1,DUT,IMPAD1,ADCY9,PPCDC,UPRT,NDUFB9,SLC26A2,TALDO1,GPD1L,OGG1,KCNAB2,ADCY7,CGAS,ATP6V0A1,RRM2,OGDH,NDUFA7,NDUFB1,TAZ,PRPSAP1,PDHX,MPC1,STOML2,HINT1,GUCY1B1,NT5C3B,NDUFA11,COX5A,DHTKD1,UQCRH,MAPK1,NUDT11,PFKP,GALK1,NADSYN1,NDUFV2,COX5B,NDUFS1,MECP2,RRM1,RAB23,TKT,NDUFA4,COX4I1,ABHD14B,CYCS,ATP5F1B,NDUFS7,HDDC2,NEIL2,NDUFS4,ERH,NDUFV1,GART,NDUFA2,NDUFB4,ATIC,CTPS1,MSH2,TPST1,ATP6V0A2,NDUFS8,CYC1,NDUFA3,RNLS,LDHB,AMPD2,TGFB1,RHOA,TK1,GUK1,NUDT4,LDHA,NADK2,ADSL,DCTD,PKM,ATP5MF,PDE3B,HSPA1B,ADSS,MBIP,ATP5MC3,PARG,DCK,PRPS2,COX7A2L,ACLY,COX8A,TBPL1,NAXE,IMPDH1,ACAT1,MDH1,DNPH1,NDUFS5,GPI,ATP5F1A,NIPSNAP2,PARP10,PGAM1,NUDT3 |
| 4.129e-08 | -17.00 | RPS4X (ribosomal protein S4, X-linked) | protein interactions | 6191 | 203 | 64 | 17029 | 2761 |
CYLD,NOP2,RPLP2,EIF3D,CUL1,BRIX1,GGPS1,RPL11,RPL23A,KRR1,EXOSC1,TARDBP,CDC5L,RPL29,RPL35,RPL38,CUL3,AURKB,MCM2,SLC25A5,GAR1,RPS9,RPSA,RPS27A,RPS14,RPLP1,COPS6,RRS1,FAU,ARRB2,SMURF1,RPS26,RPS15,RPS2,RPL15,HUWE1,RPL17,PTEN,AHSA1,RPL19,FBL,PABPC1,HNRNPM,LUC7L2,SLC25A1,STAU1,EIF3L,DDX24,RPL8,ILF3,RPL6,RPS10,RPS24,RPL27A,CAND1,RPL36,NAP1L1,RPL32,HNRNPH3,RUVBL2,CD81,CDK2,SSSCA1,BYSL |
| 4.131e-08 | -17.00 | PIN1 (peptidylprolyl cis/trans isomerase, NIMA-interacting 1) | protein interactions | 5300 | 247 | 74 | 17029 | 2761 |
TSC2,RAF1,CSNK2A1,IRF3,CCNB1,ATP6V1B2,REPS1,APP,NEK6,ETV6,RAB4A,CDKN1B,ZBTB22,TFG,CDK12,PCBP2,CFL1,GPX4,PLK1,DEAF1,UBQLN4,SNRNP200,ZCCHC10,AATF,VHL,RNPS1,SREK1,MCL1,NFATC2,NDUFA7,PKMYT1,EIF3G,DHX15,DDX17,PPP2CA,SMAD2,HINT1,AXIN1,CEP55,UHRF2,PTOV1,CASP6,ATP5F1B,THRAP3,GGA2,CDK11B,SPR,PIP4K2A,WRNIP1,CCNK,FKBP1A,KLHL20,SSBP3,EFTUD2,BCL2,TAGLN2,PABPC1,SRSF11,DDX24,KRAS,BCLAF1,PKM,CDK11A,FADD,POLR2A,CDC27,GOLGA2,QARS,PML,KMT2B,NUP62,DDX5,CDK2,DDB1 |
| 4.139e-08 | -17.00 | GSE12392_WT_VS_IFNB_KO_CD8A_NEG_SPLEEN_DC_UP | MSigDB lists | GSE12392_WT_VS_IFNB_KO_CD8A_NEG_SPLEEN_DC_UP | 189 | 58 | 17377 | 2626 |
TCF12,CTDP1,GOLIM4,MRPL42,NOP2,LUZP1,CASP6,PHB2,DLGAP4,ASAH1,AGPAT3,TAF6L,AP3S1,SYNRG,LRRC14,RBM17,FKBP1A,CAPN2,ASAP2,NEK6,ATIC,RABGAP1L,PELO,FNIP2,PDIA6,PPA1,TMBIM1,RNF169,PPAN,CYTH1,TSTA3,VHL,SLC26A6,LDHA,USP10,USP22,ASB13,IRF5,CYB5A,GLOD4,MAP3K4,TRAM2,ZNF282,SCARB2,C1orf131,TXNDC16,TWSG1,HIPK2,DBI,MYO18A,MPV17,SLC16A1,MBOAT1,WDR91,TFDP2,ATMIN,ALS2,STARD3NL |
| 4.139e-08 | -17.00 | GSE41867_NAIVE_VS_DAY15_LCMV_ARMSTRONG_EFFECTOR_CD8_TCELL_UP | MSigDB lists | GSE41867_NAIVE_VS_DAY15_LCMV_ARMSTRONG_EFFECTOR_CD8_TCELL_UP | 189 | 58 | 17377 | 2626 |
EXOC3,DDX47,NQO1,TRIP10,GNE,COPE,MON1B,PLAGL2,MYEF2,RAD23A,LRRC14,CCNK,DECR1,HOMER1,SNUPN,CBWD2,TRMU,TNPO2,TNPO3,TAP2,MINPP1,RNF135,RPRD1B,PREB,EXOSC6,MKLN1,KAT2A,GABPA,POLK,OAF,LYRM1,CRNKL1,GTPBP4,DNAJC9,SUMF2,TMEM147,GALNT7,GSTCD,MAP2K2,ZDHHC3,SF3A2,MAT2A,USP36,C1orf122,ABHD5,CHCHD3,DNAJC10,KEAP1,PDCD6,POLR2J,CDC27,SNAP23,LMBR1,SEL1L,PIAS2,GAS2,LRP8,NXT2 |
| 4.143e-08 | -17.00 | GINESTIER_BREAST_CANCER_20Q13_AMPLIFICATION_DN | MSigDB lists | GINESTIER_BREAST_CANCER_20Q13_AMPLIFICATION_DN | 149 | 49 | 17377 | 2626 |
CCDC93,EXOC3,EWSR1,KDM4A,ZNF316,RPS6KA1,WDTC1,SMC6,MYO9B,SUPT7L,SNAPC4,QSOX2,KIAA1147,C2orf68,MBD4,KIFC1,FANCL,MCM5,RAB35,DNM2,CHTOP,FBXL19,NSUN4,CAMK2G,SMC4,ACSL5,ANKLE2,ARHGAP17,CYTH1,PRRC2A,BTAF1,PSPC1,PGS1,MKI67,PCGF6,RNPS1,TAZ,BRD2,HINT1,CLK3,DHX16,GRIPAP1,HNRNPH3,TYW5,PROSER1,NUP62,TCOF1,SMARCD1,FUBP1 |
| 4.153e-08 | -17.00 | RPS15 (ribosomal protein S15) | protein interactions | 6209 | 144 | 50 | 17029 | 2761 |
RPS2,CYLD,NDUFS1,RPLP2,FLOT1,RPL15,CUL1,PAIP1,RPL11,RPL23A,MDM2,RPL17,AHSA1,ZNF746,ATP6V0A2,RPL19,UPF2,RPS10,RPL6,RNPS1,CUL3,RPL8,ATP6V0A1,RPS24,CADM1,RPL27A,MAK16,RPS9,RPSA,CAND1,RPL36,RPL37,MRPL2,ATP6V1D,C1orf131,SEC61A1,RPL32,RPS14,RPLP1,MPV17,H2AFX,DUSP11,RRS1,FAU,SMURF1,CD81,RPS26,MRPL3,ZC3HAV1,FUBP1 |
| 4.162e-08 | -16.99 | CYP1A1 (cytochrome P450 family 1 subfamily A member 1) | protein interactions | 1543 | 71 | 31 | 17029 | 2761 |
RECQL,USO1,BRD4,RPRD1A,MUT,SNX2,NSDHL,EIF2A,PKM,MCM2,EIF4G2,PICALM,CYB5A,MCTS1,AFDN,GSTK1,NUCB1,EIF2S2,ADD3,CTNNBL1,PPP1R8,PIN1,TPP2,TXLNA,PTPN11,NAA50,CAB39,DTD1,TCEA1,MINPP1,CSTF1 |
| 4.166e-08 | -16.99 | GSE32533_WT_VS_MIR17_KO_ACT_CD4_TCELL_DN | MSigDB lists | GSE32533_WT_VS_MIR17_KO_ACT_CD4_TCELL_DN | 180 | 56 | 17377 | 2626 |
CORO7,ZCCHC9,PHF23,VPS45,DAZAP2,TWF2,PSEN1,METTL3,GIT2,MAD2L2,SEC11A,VAV1,RB1,SMC3,PDCD10,ZNF449,SP100,KLHL5,ZNRF2,PHTF1,RNASEK,ZDHHC13,AP2B1,GLE1,ARID4A,CFL1,HP1BP3,CYTH1,AGGF1,BRD4,ZMYND11,ELP4,RABIF,FBXO9,ESYT1,ZNF407,PDE3B,SLTM,RAB2B,FAS,DDX17,PCM1,FNTA,TAB2,CSK,OSBPL8,TFDP1,HMGB2,FBXL3,NDE1,CDK2,ARRB2,FAM208A,PURA,N4BP2L2,TMEM131 |
| 4.166e-08 | -16.99 | GSE21033_CTRL_VS_POLYIC_STIM_DC_3H_UP | MSigDB lists | GSE21033_CTRL_VS_POLYIC_STIM_DC_3H_UP | 180 | 56 | 17377 | 2626 |
RHOG,ANKRD27,PKP4,SH2D3A,ADAM10,ZNF768,HMGN3,TBC1D13,ORC1,SUPT7L,PRKACA,REPS1,RSAD1,PCYOX1L,GSTK1,SNUPN,SLC1A4,MTMR4,CRAT,FUT8,RAB4A,EI24,BRD7,MDFIC,NAP1L4,ACAD8,LPCAT1,SCYL3,HTRA2,EBAG9,NIPAL3,PTPN18,DDX24,CREG1,RPS24,RABIF,FXR1,KIF11,TTC33,AKAP1,PRIM1,MTMR3,HINT1,RBM25,ELMO1,PRDX3,FASTK,ARNTL,LPCAT4,MEGF9,ZDHHC7,FN3KRP,MRFAP1L1,RBPJ,AP2S1,ANXA11 |
| 4.166e-08 | -16.99 | GSE41867_DAY8_EFFECTOR_VS_DAY30_EXHAUSTED_CD8_TCELL_LCMV_CLONE13_UP | MSigDB lists | GSE41867_DAY8_EFFECTOR_VS_DAY30_EXHAUSTED_CD8_TCELL_LCMV_CLONE13_UP | 180 | 56 | 17377 | 2626 |
SRM,CCNC,PLXNC1,ADD1,COPA,MRPL42,NDUFB6,PHRF1,WDR13,PTTG1,CUTA,RRM1,NDUFA4,ORC1,SND1,PCBP1,TMEM165,RAB11A,EBP,SEC11A,LYAR,MED8,PIN1,MEGF8,HADHB,RPN2,TTLL12,NUP85,PACS2,POC5,EIF5A,TIMM8B,DDX24,AATF,RBX1,PPT1,BTAF1,LRRC8A,RFFL,ABHD11,NUTF2,RAB1A,SHCBP1,ABCF1,STOML2,EVC2,AKAP1,AMZ2,AHNAK,BIRC5,UBXN2B,CAPN7,PRDX5,ITGB1,REEP4,TSPAN5 |
| 4.226e-08 | -16.98 | TOP2A (DNA topoisomerase II alpha) | protein interactions | 7153 | 116 | 43 | 17029 | 2761 |
UNK,COX15,NOP2,KMT2E,NF1,CDT1,SUMO2,RAC1,DHX9,CTCF,CSNK2A1,TOP2B,BLM,UBE2I,CDC73,LMNA,RPA2,RB1,MCM5,PIN1,AHSA1,MSH2,TFG,TERF2,CDC5L,PLK1,VHL,CDC6,BRCA1,VDAC1,PATL1,ISG15,RPA1,XRCC5,MAP3K4,PALB2,L3MBTL3,E2F4,H3F3A,MAPK1,HDAC2,IFI16,SSRP1 |
| 4.299e-08 | -16.96 | RPS26 (ribosomal protein S26) | protein interactions | 6231 | 136 | 48 | 17029 | 2761 |
RPS15,RPS2,CYLD,RPLP2,NDUFAF2,DHX9,RPL15,NENF,SND1,TMEM165,APP,PNO1,RPL11,RPL23A,MDM2,PTEN,RPL17,RPL19,TMED2,HNRNPM,SLC25A1,SRPK2,RPL29,RPL35,RPS10,RPL6,ILF3,RPL8,RPL38,TUFM,RPS24,MCM2,RPL27A,RHOT2,RPS9,TSR2,RPSA,EIF3A,RPL36,EIF3K,RPL32,RPS27A,RPS14,RPLP1,FAU,ECPAS,DYNC1LI2,BYSL |
| 4.339e-08 | -16.95 | regulation of protein catabolic process | biological process | GO:0042176 | 360 | 94 | 17256 | 2622 |
USP7,ATXN3,SUMO2,CSNK2A1,SIRT2,UBQLN2,PRKACA,BCAP31,ANKIB1,RIC1,PARK7,FBXO22,USP5,RAD23A,RPL11,UBXN2A,PSMD1,MDM2,PIN1,UCHL5,DDA1,RAD23B,CDKN1B,RNF19A,TIPARP,SENP1,PDCL3,RYBP,PLK1,PLK3,UBQLN4,TIMP2,RBX1,RAB7A,PBK,EZR,EDEM2,ODC1,IDE,PSMD3,HIPK2,AXIN1,ARNTL,SOCS4,OGT,ADAM9,CHEK2,TRIM32,CLU,DVL1,ROCK1,SMURF1,PSMC1,OAZ1,CSNK1D,SVIP,USP13,GGA1,UBXN1,NKD2,CSNK1A1,PSEN1,MAD2L2,WWP2,DDRGK1,DTL,PSMD2,PTEN,LPCAT1,SOCS5,ATP5IF1,LONRF3,TNFAIP3,GBA,PTTG1IP,PSMC4,HSPA1B,GNA12,KEAP1,HSPBP1,HGS,NSF,OAZ2,PML,FAM83D,CTSA,WDR91,SNRNP70,CD81,RNF14,RNF139,FAF1,DDB1,RNF114 |
| 4.340e-08 | -16.95 | YY1 (YY1 transcription factor) | protein interactions | 7528 | 132 | 47 | 17029 | 2761 |
MAX,KMT2E,SUZ12,MECP2,RAF1,TCF3,AGO2,CTCF,INO80E,PSMD9,APP,CRKL,FKBP1A,PPP1R3B,RB1,MDM2,UCHL5,CREB1,ATF2,TERF2,RYBP,SAP30,SP3,GABPA,MTA2,PRKDC,ILF3,E2F3,WDHD1,BRCA1,FKBP3,XRCC5,SMAD2,HSPA4,UHRF2,DDX5,ATF6,ZRANB2,RUVBL2,YY1,SMAD1,ZNF830,E2F2,TERF1,SMAD4,CDKN2A,HDAC2 |
| 4.440e-08 | -16.93 | TGCGCANK_UNKNOWN | MSigDB lists | TGCGCANK_UNKNOWN | 500 | 121 | 17377 | 2626 |
IMMT,GGNBP2,CKLF,FLYWCH2,PPP1R15B,MAGED1,WDTC1,XIAP,PMS2,KLHL18,SMARCA4,FKBP2,SDHA,ABHD14A,CALM2,HNRNPA2B1,FANCL,CYHR1,NRF1,USF1,WDR44,ATG3,RAB35,PPME1,POP7,XRCC2,AP2B1,TECR,GPD1L,DNMT1,MTPN,DVL2,MRPL32,PCBP2,GPX4,CSTF1,CDC5L,KAT7,GOPC,PCGF6,PKMYT1,ICMT,KRTCAP2,CHMP2B,TOLLIP,SRSF1,CCDC127,EIF3K,HINT1,SAFB,RNF38,ATXN2L,CAB39,AP1S1,ARRB2,NUDT11,ZMAT3,CBX4,NUMB,OTUD5,EWSR1,PPP1R12A,SHPRH,MECP2,MRI1,CDK2AP2,RAB23,TIA1,SIKE1,ABHD14B,ADCK5,IFT27,PDXDC1,JAKMIP1,TFAP4,EIF2S2,DAD1,MEA1,MSH2,RPL19,UPF2,KIFAP3,PCYT2,CREB1,PABPC1,UBE2M,TMX1,PREB,EIF5A,RHOA,KAT2A,TMEM39A,PSPC1,RFXANK,FBXO9,RABIF,MAP4K3,SRSF5,PCGF1,METTL22,ARSK,EIF4G2,KDM3A,ARMC8,POLR2A,XRCC5,CBX3,MAGED2,RAB18,SEC23IP,PALB2,PRDX3,COX7A2L,VCPIP1,FAM122A,RBPJ,PLOD3,SNRNP70,RUFY3,NR2F2,USF2 |
| 4.474e-08 | -16.92 | PSMC2 (proteasome 26S subunit, ATPase 2) | protein interactions | 5701 | 165 | 55 | 17029 | 2761 |
CYLD,ZCCHC8,UBR2,UFC1,DCTN2,PMS2,POMP,UBQLN2,PSMD9,SDHA,CDC73,UBLCP1,GTF2F1,RAD23A,PTPN2,HERC3,RPN1,PSMD2,PSMD1,SMC3,PSMA6,HUWE1,UCHL5,RAD23B,YBX1,CRY2,FTSJ3,CDC5L,LDHB,TXNL1,CCT2,SNRNP200,PSMA8,LDHA,CUL3,PSMB7,PSMA1,BRCA1,DNAJA1,MCFD2,PSMB9,CCT8,PSMB3,PSMC4,DERL1,HSPA4,PSMD8,PSMD3,ACADM,MAP3K5,ECPAS,UBE2C,PSMC1,IPO4,TUBB |
| 4.531e-08 | -16.91 | MORI_EMU_MYC_LYMPHOMA_BY_ONSET_TIME_UP | MSigDB lists | MORI_EMU_MYC_LYMPHOMA_BY_ONSET_TIME_UP | 99 | 37 | 17377 | 2626 |
ZBED3,DDX47,PHB2,SUZ12,TCF3,SUMO2,SMARCA4,CBLL1,INO80E,SPAG5,ZNF428,STRBP,DNAAF2,PRDM4,EFTUD2,AHCY,ELOF1,JMJD4,RFC3,PRIM2,SNRPB,ILF3,WDHD1,CYFIP2,TRIM28,FKBP3,GEMIN5,CDCA4,KIF18B,LSM6,DCK,MRPL27,COX5A,SMPD4,RBBP4,TRAF5,SSRP1 |
| 4.532e-08 | -16.91 | GO_POSITIVE_REGULATION_OF_PROTEASOMAL_PROTEIN_CATABOLIC_PROCESS | MSigDB lists | GO_POSITIVE_REGULATION_OF_PROTEASOMAL_PROTEIN_CATABOLIC_PROCESS | 95 | 36 | 17377 | 2626 |
GORASP1,DNAJB2,SUMO2,NKD2,SIRT2,UBQLN2,CSNK1A1,PSEN1,ANKIB1,BCAP31,FBXO22,DDRGK1,USP5,FBXO5,RB1,MDM2,PTEN,RNF19A,SOCS5,PLK1,PLK3,CUL3,RAB1A,PSMC4,HSPBP1,KEAP1,GOLGA2,NSMCE2,SOCS4,DVL1,CLU,RNF14,PSMC1,ESPL1,CSNK1D,RNF114 |
| 4.542e-08 | -16.91 | Mitotic G2-G2/M phases | REACTOME pathways | R-HSA-453274 | 184 | 60 | 10287 | 1696 |
FGFR1OP,MAPRE1,PPP1R12A,FOXM1,DYNLL1,DCTN2,CENPF,TPX2,CUL1,HAUS4,CCNB1,CDK11B,PRKACA,PSMD9,HAUS2,TUBGCP2,LIN9,PSMD2,RAB8A,PSMD1,PSMA6,CCNA2,CCP110,CENPJ,GTSE1,FBXL7,CDC25B,CEP63,DCTN1,PLK1,PSMA8,RBX1,MYBL2,TUBGCP5,PSMB7,E2F3,PSMA1,PKMYT1,BORA,PSMB9,CDK11A,PSMB3,PSMC4,OPTN,HAUS8,PPP2CA,PCM1,RPS27A,PSMD8,PSMD3,ODF2,E2F1,SSNA1,NDE1,RBBP4,CDK2,CCNB2,PSMC1,TUBB,CSNK1D |
| 4.558e-08 | -16.90 | GSE40274_CTRL_VS_EOS_TRANSDUCED_ACTIVATED_CD4_TCELL_UP | MSigDB lists | GSE40274_CTRL_VS_EOS_TRANSDUCED_ACTIVATED_CD4_TCELL_UP | 167 | 53 | 17377 | 2626 |
CTU2,GOLIM4,CLSPN,TPX2,CDCA3,CDCA8,KIF23,SUMF1,RACGAP1,NUF2,STMN1,TCF19,SPAG5,GNS,DTL,CDKN2C,RB1,CCNA2,SP100,KIF14,RNASEK,PRC1,GTSE1,SEPT11,KIF22,KNTC1,MYBL1,F2R,TACC3,NASP,OXR1,KIF15,MKI67,CKAP2L,CDCA2,AURKB,ADRB2,ANLN,SHCBP1,KIF11,ASF1B,MASTL,MID1IP1,KIF18A,KIF18B,BIRC5,KLHL15,UBXN2B,NEIL3,CDCA5,ZMIZ1,GEN1,E2F2 |
| 4.622e-08 | -16.89 | GSE40274_CTRL_VS_FOXP3_TRANSDUCED_ACTIVATED_CD4_TCELL_UP | MSigDB lists | GSE40274_CTRL_VS_FOXP3_TRANSDUCED_ACTIVATED_CD4_TCELL_UP | 185 | 57 | 17377 | 2626 |
WSB2,ZBED3,MCM10,MAGED1,PTTG1,DBF4,RRM1,HMGN3,NANS,PMF1,FKBP2,S1PR2,NCAPG,TCF19,POLR3K,FANCI,OIP5,CDKN2C,PSMA6,SLC1A4,SIVA1,PPP6C,BTF3L4,CS,TIMELESS,KIFAP3,KNTC1,SLC12A2,ARL5A,ALDH9A1,GINS1,PHF10,RFC3,PRIM2,RAD51AP1,ATP6V0A1,CKAP2L,NUSAP1,EXOSC9,AURKB,SMC2,EIF2A,EAF2,RFC2,SNRPA,ASF1B,MASTL,RAD51C,SLCO4A1,MTHFD2,POLE,KIF18B,WNT5B,CEP55,PPP2R2D,SLC25A33,VPS29 |
| 4.622e-08 | -16.89 | GSE5679_CTRL_VS_PPARG_LIGAND_ROSIGLITAZONE_TREATED_DC_UP | MSigDB lists | GSE5679_CTRL_VS_PPARG_LIGAND_ROSIGLITAZONE_TREATED_DC_UP | 185 | 57 | 17377 | 2626 |
KARS,NUP188,CLSPN,CDCA3,OLA1,KIF23,GTF3A,KIF2C,PMF1,BCL2L1,STMN1,FBXO5,LYAR,CCNA2,CTNNBL1,TIMM23,AHSA1,UCHL5,MCM5,SEPT11,YBX1,PDIA6,LRRC59,PPA1,TACC3,EIF3L,PSRC1,LAP3,ASPM,MKI67,TBRG4,NUSAP1,EXOSC9,BRCA1,TMEM147,GAR1,SHCBP1,DDX39A,MRPS14,SNRPA,ASF1B,RAD54B,PRIM1,STOML2,MTHFD2,KIF18B,MRPL27,H2AFX,SLC16A1,NUP62,KPNA2,ANP32E,CCNB2,MRPL3,GCSH,TUBB,GPATCH4 |
| 4.622e-08 | -16.89 | GSE37532_TREG_VS_TCONV_CD4_TCELL_FROM_LN_DN | MSigDB lists | GSE37532_TREG_VS_TCONV_CD4_TCELL_FROM_LN_DN | 185 | 57 | 17377 | 2626 |
PPIB,MIF4GD,NOP2,SYS1,CASP6,CHD1L,HEXB,ARID5A,C5orf30,PLAGL2,SLC20A1,BIRC2,TFRC,KIAA1147,LYAR,UBXN2A,CTSS,EXOSC7,DAD1,RAB35,TBC1D14,TANK,ETV6,RRBP1,SRI,PPP1R12C,NOC2L,BCL2,RP2,NDUFA3,MGAT5,HTRA2,KCNAB2,PPAN,PLK3,FTL,KAT2A,SIGMAR1,LAP3,NSUN2,UTP15,NDUFA7,STOML2,HLA-B,EPRS,SLC19A1,TMEM41A,DUS3L,GRIPAP1,TBL3,STAT6,NFIL3,ARAP1,NLRC5,CLN3,ATP6V0E1,GPATCH4 |
| 4.622e-08 | -16.89 | GSE24634_TREG_VS_TCONV_POST_DAY3_IL4_CONVERSION_UP | MSigDB lists | GSE24634_TREG_VS_TCONV_POST_DAY3_IL4_CONVERSION_UP | 185 | 57 | 17377 | 2626 |
TMEM106C,SRM,MCM10,TMEM184B,HNRNPAB,CDT1,CENPF,DBF4,TAP1,RRM1,CDCA8,RACGAP1,BCL2L1,FAM136A,SNRPD3,BLM,POLR3K,BZW2,PNO1,DTL,NUP210,NVL,ATIC,FUT8,POP7,AKAP8,CS,ATP6V0A2,PDCD2,KNTC1,RNASEH2A,MCPH1,UBE2M,ILKAP,MICAL3,TACC3,HNRNPM,GINS1,PLK1,CCT2,MYBL2,MKI67,EZR,BORA,DDX39A,ODC1,TARS,SUPT16H,ABHD5,FBXO41,KIF18A,POLE,UAP1,HINT1,CRCP,TMEM14A,BYSL |
| 4.669e-08 | -16.88 | RPN1 (ribophorin I) | protein interactions | 6184 | 161 | 54 | 17029 | 2761 |
WSB2,PPIB,COX15,SND1,UBQLN2,SDHA,CDC73,SSR1,RAD23A,GSTK1,ZNF746,SUCLG2,NDUFB9,CRY2,RPN2,BCAP29,CYC1,TECR,PDIA6,ATF2,ATP6V0D1,PRPF19,CDC5L,STAU1,UBQLN4,RPL35,IDH3A,VDAC2,CUL3,ILF3,TUFM,SSR2,ADRB2,PKM,VDAC1,MCM2,RAB1A,SLC25A5,DDX39A,RAB5B,CCT8,RPSA,NCDN,EVC2,DERL1,ATP1A1,SYNCRIP,DDOST,SEL1L,ACADM,ATP5F1A,RBBP4,CLN3,PSMC1 |
| 4.669e-08 | -16.88 | RPS20 (ribosomal protein S20) | protein interactions | 6224 | 161 | 54 | 17029 | 2761 |
RPS2,CYLD,RPLP2,EIF3D,AGO2,RPL15,CUL1,SND1,APP,TUBGCP2,PNO1,RPL11,RPL23A,MDM2,PTEN,RPL17,AHSA1,EXOSC1,RPL19,TARDBP,RPL29,EIF3L,NRAS,RPL35,RPS10,RPL6,CUL3,ILF3,RPL8,RPL38,TUFM,RPS24,MCM2,RPL27A,RPS9,RPSA,EIF3A,EIF3H,POLR2A,CAND1,RPL36,SYNCRIP,RPL32,RPS14,MAP4,RPLP1,PGRMC1,DDX5,COPS6,RRS1,FAU,CDK2,SMURF1,RPS26 |
| 4.709e-08 | -16.87 | RODRIGUES_THYROID_CARCINOMA_POORLY_DIFFERENTIATED_DN | MSigDB lists | RODRIGUES_THYROID_CARCINOMA_POORLY_DIFFERENTIATED_DN | 708 | 160 | 17377 | 2626 |
ZBED3,MIB2,UBL3,PNISR,ADD1,NF1,GPBP1L1,RBM8A,SLC29A1,ABHD14A,MRPL19,PAPOLA,RAP1A,SRSF4,XRCC2,SRI,SMARCE1,PCBP2,USP34,AKT2,DPYSL3,UBTF,ANKRD10,HHEX,HSPB11,WDR11,TMED10,U2SURP,CLU,GALNT10,GLCCI1,CHPT1,ZNF75A,LONP2,CAPN1,PDCD4,UBE2D3,DNAJC5,DNAJB2,SDC2,MED13L,RPL15,CDK13,PPP3CB,XPO7,ZNF518A,ARID1B,HAUS2,CFLAR,CD59,TNS3,INPP5A,FBXO7,BCL2,PIK3IP1,ACAD8,RNF135,FDFT1,SRSF11,CYTH1,ELL2,TSPAN31,DCAF8,DCTD,AKAP1,DTWD1,CAT,GNAS,SCARB2,GOLGA4,SERF2,SNAP23,PITPNA,PPP6R3,PPP6R2,MAP3K5,EHD4,RBBP4,MYO9A,PDLIM5,TOB1,NUDT3,ZNF207,NDUFA5,ATXN3,CYLD,GGNBP2,ARID2,ZFYVE21,CHKB,EPM2A,C2orf68,ANKRD28,PDK2,APLP2,TNFAIP8,STRBP,PDCD2,METTL9,GPD1L,TMBIM1,KDM3B,ERMP1,CIRBP,ATXN1,HTATIP2,NLN,DCLRE1C,ATP1A1,TAB2,HIPK2,GADD45B,PPA2,RNF38,WDR7,FKBP5,H3F3A,TSPAN5,SMAD4,LRP8,CASP6,SLC41A1,MRI1,FAM76A,TRAK1,CCDC28A,TMCC3,FBXO3,ADD3,ITGB8,PTEN,NDUFB4,RRBP1,PELO,SLC38A10,NDUFS8,CITED2,TPCN1,TSHZ1,NIPAL3,TXNL1,YTHDC1,TNFAIP3,CSRP1,NET1,PPP1R21,RFFL,FBXO9,PRMT2,KLF6,BSDC1,MTMR3,FBXO21,RAB18,ACOX1,BBX,FAM3C,SRSF3,NR2F2,HIPK3 |
| 4.771e-08 | -16.86 | Mitotic Metaphase and Anaphase | REACTOME pathways | R-HSA-2555396 | 180 | 59 | 10287 | 1696 |
MAPRE1,PTTG1,CENPF,CDCA8,NUF2,KIF2C,PMF1,SPDL1,PSMD9,LMNA,MIS12,FBXO5,PSMD2,PSMD1,SMC3,AHCTF1,PSMA6,BANF1,NUP107,PDS5B,ANAPC7,KNTC1,CENPM,NUP85,SEH1L,NUDC,ANKLE2,PLK1,PSMA8,TAOK1,PSMB7,PSMA1,ANAPC2,RANGAP1,AURKB,CDC23,PSMB9,PSMB3,CENPU,PSMC4,KIF2A,PPP2CA,LEMD2,CDC16,KIF18A,PPP2R5A,DSN1,CDC27,BIRC5,RPS27A,PSMD8,PSMD3,CDCA5,CENPT,NDE1,UBE2C,PSMC1,ESPL1,ANAPC4 |
| 4.869e-08 | -16.84 | GO_TRANSLATIONAL_INITIATION | MSigDB lists | GO_TRANSLATIONAL_INITIATION | 141 | 47 | 17377 | 2626 |
RPS15,RPS2,RPLP2,EIF3D,RPL15,EIF1B,RBM4,PAIP1,RPL11,RPL23A,MCTS1,EIF2S2,RPL17,RPL19,EIF5,PABPC1,PCBP2,RPL29,EIF3L,RPL35,CDC123,DHX29,RPS10,RPL8,RPL38,RPL6,RPS24,EIF2A,RPL27A,EIF4H,EIF4G2,ABCF1,RPS9,EIF3G,RPSA,EIF3A,EIF3H,RPL36,RPL37,EIF3K,RPL32,RPS27A,RPS14,EIF2D,RPLP1,FAU,RPS26 |
| 4.894e-08 | -16.83 | GO_TRANSCRIPTION_COUPLED_NUCLEOTIDE_EXCISION_REPAIR | MSigDB lists | GO_TRANSCRIPTION_COUPLED_NUCLEOTIDE_EXCISION_REPAIR | 72 | 30 | 17377 | 2626 |
COPS8,USP7,ERCC1,HMGN1,RFC3,POLR2I,POLR2G,POLR2L,POLR2K,RBX1,POLK,XAB2,PPIE,POLR2D,RFC2,POLR2A,RPA1,RPA2,PCNA,POLR2J,RPS27A,XPA,COPS7B,TCEA1,AQR,COPS6,ZNF830,GTF2H2,DDB1,PRPF19 |
| 4.937e-08 | -16.82 | VPS29 (VPS29, retromer complex component) | protein interactions | 51699 | 75 | 32 | 17029 | 2761 |
CCDC93,USP7,COMMD10,ANKRD27,JMJD6,PAWR,COMMD5,RGS2,COMMD6,COMMD8,VPS25,APP,SAC3D1,GTF2F1,NDUFV1,TTC4,TMEM9,NUDC,SNX2,RAB7A,NADK2,UBE4B,TOLLIP,COMMD4,ZFR,VPS26C,VPS26B,PPM1G,STAT1,PSAP,ATP6V1C1,H3F3A |
| 4.942e-08 | -16.82 | GO_CELL_DEATH | MSigDB lists | GO_CELL_DEATH | 973 | 208 | 17377 | 2626 |
DDX47,MAX,PDCD6IP,THOC1,NF1,TMEM109,XIAP,UBE2Z,CSNK2A1,CUL1,SIRT2,MAPK14,BECN1,MIEN1,BIRC2,PARK7,CDK5,NEK6,GSDMB,ATG3,SIVA1,NOC2L,FNIP2,SENP1,CCAR1,DRAM2,TIMM50,RYBP,PLK3,PGAP2,BAK1,AKT2,LRP5,TOPORS,MCL1,BRCA1,DIDO1,EAF2,STK17B,OPTN,BRMS1,AXIN1,PRDX5,OGT,BCL7C,STK11,ROCK1,CLU,CHEK2,ARRB2,TRAF5,E2F2,RTN3,ZMAT3,PDCD4,SMNDC1,UBE2D3,CLSPN,GADD45G,CIB1,TIA1,MEF2A,CYCS,NOTCH2,NCKAP1,PDCD7,PSEN1,APOPT1,RHBDD1,CFLAR,RTKN,TFAP4,RB1,DAD1,HDAC7,XPA,EI24,ARL6IP1,DAPK1,MSH2,BCL2,EIF5A,PIGT,NOA1,BCLAF1,UBE4B,CYFIP2,FXR1,EIF4G2,SLTM,APPL1,RHOB,DAPK3,FAS,KPNA1,FNTA,SIAH2,NUP62,GPI,MAP3K5,CDKN2A,ALS2,SART1,DNMT3A,CYLD,TRAF7,RPS6KA1,DYNLL1,RAF1,TPX2,RRAGC,IRF3,BCL2L1,DUSP22,BCAP31,APP,MOAP1,PDK2,MDM2,TNFAIP8,RALB,SIAH1,CDKN1B,PDCD2,TARDBP,BCAP29,TP53BP2,F2R,ATF2,HTRA2,PDCL3,EBAG9,PPIF,POLR2G,BIRC3,TAOK1,CUL3,HTATIP2,MEF2D,CADM1,VDAC1,PPP2CA,DNAJC10,DAP3,HINT1,FASTK,HIPK2,GADD45B,STAT1,TICAM1,GAS2,MAPK1,EYA2,BCL2L12,GCLM,MAGEH1,NDUFS1,ANXA6,TMBIM4,CASP6,DAP,SRGN,PAWR,CDK11B,FOXO3,MFSD10,FGFR3,PDCD10,CLIC4,CTNNBL1,PTEN,FEM1B,PACS2,MSH6,TGFB1,PDPK1,ACP2,TNFAIP3,PRKDC,PARP4,JTB,RFFL,EMP3,PNPLA8,RHOT1,RHOT2,API5,CDK11A,SH3GLB1,FADD,MFN2,MAPK3,PDCD6,PRDX3,BIRC5,ELMO1,E2F1,PML,TMEM219,AEN,HMGB2,DDX5,IGBP1,HIPK3,ESPL1,HRAS,FAF1,IFI16 |
| 4.958e-08 | -16.82 | TCCCRNNRTGC_UNKNOWN | MSigDB lists | TCCCRNNRTGC_UNKNOWN | 199 | 60 | 17377 | 2626 |
OTUD5,UBL3,HSPH1,LZTR1,ZCCHC8,TSC22D3,ADO,PLAGL2,CSNK2A1,SLC4A2,COX4I1,ASXL2,STMN1,POFUT1,MYL6B,CCDC28A,FBRS,KRR1,CDK5,ZNF428,TFAP4,MRPL50,PA2G4,GART,CCP110,CD3EAP,PPP1R8,SCAMP4,CYB5R1,ZNF189,PRPF19,PLK1,YTHDC1,EIF5A,TMEM115,RHOA,KAT2A,POLK,RB1CC1,RDH10,NFATC2IP,NUTF2,RAB1A,VKORC1,KIF11,SRSF1,ADSS,CHCHD3,BRMS1,PCM1,RPS27A,LUC7L3,KBTBD7,EXOC4,SEL1L,KHSRP,MBD6,RRS1,RUFY3,TMEM33 |
| 5.028e-08 | -16.81 | GCM_MYST2 | MSigDB lists | GCM_MYST2 | 163 | 52 | 17377 | 2626 |
RBM8A,STRN4,CDIPT,FOXO3,HMG20A,FAM8A1,REPS1,PAIP1,CSDE1,FBXO3,SAP130,SMC3,MEX3C,GATC,BRPF3,RABGAP1L,PPIG,ARL6IP1,SS18L1,AHDC1,TARDBP,CHTOP,KDM3B,PHF10,SNRNP200,ZNF84,KAT7,NUDT4,ACSL3,ILF3,CRNKL1,USP22,ARID1A,PRKRA,ZFAND5,ARL5B,BSDC1,CAND1,MTMR3,VEZF1,SCARB2,EIF4ENIF1,RBM25,SYNCRIP,BRD2,VPS26B,HNRNPR,HNRNPH3,LUC7L3,CEBPG,FN3KRP,ZMIZ1 |
| 5.036e-08 | -16.80 | EBNA-LP (nuclear antigen EBNA-LP;) | protein interactions | 3783746 | 153 | 52 | 17029 | 2761 |
RPS15,RPS2,HNRNPAB,PHB2,SF3B1,MAGED1,DHX9,GLUD1,DNAJB1,SEC16A,PCBP1,RPL11,SF3B2,HNRNPA2B1,PSMD2,IARS,RPL17,CAPZA1,PCBP2,HNRNPM,TIMM50,NIPSNAP1,LDHB,SNRNP200,RFC3,IDH3A,ILF3,RPL8,RPL27A,SLC25A5,RPS9,SNRPA,SRSF1,XRCC5,DDX17,EPRS,HSPA4,SYNCRIP,TMED10,HNRNPR,RPS14,QARS,LRPPRC,ACTB,DDX5,ATP5F1A,RUVBL2,RBBP4,IDH3B,NIPSNAP2,TUBB,CDKN2A |
| 5.036e-08 | -16.80 | RPS25 (ribosomal protein S25) | protein interactions | 6230 | 153 | 52 | 17029 | 2761 |
RPS15,RPS2,CYLD,EWSR1,RPLP2,RPL15,CUL1,KIF2C,APP,LMNA,RPL11,RPL23A,MDM2,PTEN,RPL17,HUWE1,AHSA1,EXOSC1,RPL19,UPF2,TARDBP,HNRNPM,CDC5L,RPL29,EIF3L,RPL35,DDX24,RPS10,RPL6,CUL3,ILF3,RPL8,RPL38,RPS24,AURKB,BRCA1,MCM2,RPL27A,RPS9,RPSA,PHF6,EIF3A,RPL36,CAND1,RPS14,RPLP1,WDR76,RRS1,FAU,SMURF1,CD81,RPS26 |
| 5.091e-08 | -16.79 | GSE15930_NAIVE_VS_72H_IN_VITRO_STIM_TRICHOSTATINA_CD8_TCELL_DN | MSigDB lists | GSE15930_NAIVE_VS_72H_IN_VITRO_STIM_TRICHOSTATINA_CD8_TCELL_DN | 190 | 58 | 17377 | 2626 |
GALK1,CHERP,GADD45G,TMEM109,TRAK1,MOGS,OLA1,TMEM97,RRM1,TIA1,KIF23,HAUS4,POMP,INO80E,FKBP2,PRKACA,IFT27,POLR3K,MBD4,IRF4,SNRNP25,RPN1,SUB1,NDUFV1,MCM5,SIVA1,PDS5B,DNMT1,MTX2,NUP85,S100A6,TACC3,CARM1,FDFT1,ELOF1,POU2AF1,PRIM2,POLR2L,TSPAN31,RAD51AP1,MKI67,NUSAP1,BRCA1,MCM2,RFC2,MRPL2,CDKN2AIPNL,BIRC5,DCK,NAGLU,CRCP,NDUFS5,RBPJ,RNF14,PGAM1,MZT2B,GCSH,ZC3HC1 |
| 5.091e-08 | -16.79 | GSE37301_MULTIPOTENT_PROGENITOR_VS_RAG2_KO_NK_CELL_DN | MSigDB lists | GSE37301_MULTIPOTENT_PROGENITOR_VS_RAG2_KO_NK_CELL_DN | 190 | 58 | 17377 | 2626 |
MAPRE1,GOLPH3L,SCOC,SRSF6,ARGLU1,TWF2,GGPS1,SRRT,CPNE3,PABPC4,COPB2,SMC3,NEK6,EIF4A3,NVL,AKAP8,PHTF1,RNASEK,RAB4A,FOXN2,AQR,POLR1B,S100A6,PTPRK,PLK1,TGFB1,CIC,NEK7,POLR2D,LDHA,SMU1,EZR,MAP7D1,PLEC,AURKB,BRCA1,AZI2,LY6E,RAB1A,KLF6,RHOB,FAS,EIF3K,GALNT2,GOLGA7,ETS2,GADD45B,SLC16A1,CHMP4B,SRSF3,NDE1,SMAD1,ABCA1,HRAS,ZC3HC1,DDB1,CAPN1,SSRP1 |
| 5.138e-08 | -16.78 | GSE37416_CTRL_VS_48H_F_TULARENSIS_LVS_NEUTROPHIL_DN | MSigDB lists | GSE37416_CTRL_VS_48H_F_TULARENSIS_LVS_NEUTROPHIL_DN | 172 | 54 | 17377 | 2626 |
CCDC93,SNX27,TMED7,SMAP1,TRIP12,ZFP91,RBM8A,HEXB,DHX8,DNAJB1,GGPS1,HLA-A,COPB2,FBRS,PRNP,CCNK,RBM23,C18orf32,NDUFA2,EIF4A3,GMEB1,MEA1,GPATCH1,GCC1,ZC3H3,DVL2,MORC3,ATP6V1G1,SAP30,MOB4,TXNL1,COQ10B,BTAF1,E2F3,POLR2D,SMU1,USP22,TRIM28,NEU1,ARF4,C1orf122,CBX3,DERL1,BRMS1,MAGT1,GPS2,CAPN7,MAPK6,ANP32E,VPS4A,SPCS3,FAU,RTN3,ATP6V0E1 |
| 5.155e-08 | -16.78 | GSE7218_UNSTIM_VS_ANTIGEN_STIM_THROUGH_IGG_BCELL_UP | MSigDB lists | GSE7218_UNSTIM_VS_ANTIGEN_STIM_THROUGH_IGG_BCELL_UP | 181 | 56 | 17377 | 2626 |
SLC30A9,H2AFZ,MCM10,RAF1,PRKAA1,CUTA,DBF4,TMEM97,PTP4A3,NUF2,SLC4A2,KIF2C,BLM,PIP5K1C,STRBP,DAD1,BDH1,RAD23B,GTSE1,TNPO3,SLC35C2,LDLRAD3,RHBDD2,MGAT5,GINS1,CLPTM1,UBQLN4,EIF3L,SIGMAR1,ATP6V0A1,WDHD1,CKAP2L,CDCA2,TOMM40,VDAC1,H2AFV,ASF1B,MAPK3,PRIM1,TAF2,AMZ2,ALG3,MAN2A2,MOSPD3,TMEM184C,UTP20,RAB18,SCAP,DUSP3,FAM83D,CHEK2,SMPD4,PPP6R2,GLCCI1,MAPK1,TOB1 |
| 5.196e-08 | -16.77 | oxidative phosphorylation | biological process | GO:0006119 | 103 | 38 | 17256 | 2622 |
COX15,COX5B,NDUFA5,NDUFV2,NDUFS1,NDUFB6,UQCR10,MECP2,NDUFA4,COX4I1,CYCS,ATP5F1B,ATP5PF,SDHA,NDUFS7,NDUFS4,NDUFV1,NDUFA2,NDUFB4,MSH2,NDUFB9,NDUFS8,CYC1,NDUFA3,NDUFA7,ATP5MF,NDUFB1,TAZ,STOML2,ATP5MC3,NDUFA11,COX7A2L,COX8A,COX5A,UQCRH,NDUFS5,ATP5F1A,NIPSNAP2 |
| 5.212e-08 | -16.77 | nuclear outer membrane-endoplasmic reticulum membrane network | cellular component | GO:0042175 | 1066 | 221 | 18223 | 2701 |
RAB14,TMED7,PIGM,COPA,TMEM203,PIGQ,MOGS,TAP1,TMEM109,AGPAT1,FKBP2,IKBIP,CDIPT,BECN1,SEC16A,RNF103,SSR1,DST,NUP210,CDC42,THADA,CYB5RL,RAB35,SRI,ZFYVE27,CISD2,MARCH2,TECR,SPTSSA,RNF26,LRRC59,PGAP2,DPM1,ATG9A,APH1A,ESYT1,PITPNB,NUTF2,MCFD2,ICMT,KRTCAP2,RHEB,RAB2B,ALG3,AGPAT2,TMED10,STT3A,RPS27A,MIA2,SARAF,PIEZO1,CLN3,RPS26,RTN3,STARD3NL,SVIP,PIGN,AGTRAP,SEC61G,HLA-E,DNAJB2,UBXN1,SLC35B1,NOTCH2,TMED3,RAB6A,PSEN1,COPG2,RHBDD1,COPB2,NPLOC4,DDRGK1,FKBP1A,CD59,RNF121,RPN1,NUS1,PYURF,RNFT1,LRRC8D,DAD1,RTCB,EI24,ARL6IP1,PIGG,SLC27A4,BCL2,PCYT2,LPCAT1,TMED2,KDELR1,PREB,FDFT1,EIF5A,PIGT,SIGMAR1,RB1CC1,ERLIN1,NSDHL,MAN1B1,ACSL3,ERO1A,RDH10,SSR2,SYVN1,VKORC1,CYB5A,RDH11,MOSPD3,DERL1,SEC31A,SCARB2,GALNT2,ORMDL2,ERGIC3,LPCAT4,NUP62,SAMD8,SMPD4,MAP3K5,TMEM14A,PTDSS1,RNF139,APOL2,TMEM106C,RHOG,ATXN3,CHERP,RAC1,COPE,VTI1A,TMEM97,ADPGK,SLC35B2,LCLAT1,BCAP31,EXT2,KTN1,SEC11A,RAB21,ATP2A2,LPIN2,RPN2,BCAP29,TAP2,ANKRD13C,CYB5R1,AHCYL1,LMAN1,PDIA6,CLN6,HTRA2,MOSPD1,ACSL5,ANKLE2,UBQLN4,ATP13A1,ERMP1,SEC61B,TOR1AIP2,TMEM147,PKMYT1,BICD2,DNAJA1,RAB1A,SERP1,RHBDF2,DDOST,SURF4,SEC61A1,SCAP,CERS6,SEL1L,CANT1,NCLN,ATF6,MBOAT1,REEP4,ABCA1,TMEM33,CDS2,TMX3,AGPAT3,SDF2L1,WRB,DNAJB9,HLA-A,EBP,SPPL2A,SEC24C,RRBP1,SLC35B4,YIF1B,ATG13,OSTC,CAMK2G,RNF5,TMX1,ELOVL5,MLEC,RHOA,WDR81,PNPLA8,SPPL2B,YIF1A,HLA-B,PLD3,RAB18,PDCD6,MAGT1,OSBPL8,STX18,PGRMC1,LRPPRC,PML,ASNA1,PKD2,SPCS3,PLOD3,FAF1,ESYT2 |
| 5.251e-08 | -16.76 | GO_CELLULAR_RESPIRATION | MSigDB lists | GO_CELLULAR_RESPIRATION | 137 | 46 | 17377 | 2626 |
NDUFA5,COX15,NDUFV2,COX5B,NDUFS1,NDUFB6,SUCLG1,NDUFAF2,MDH2,UQCR10,MECP2,SLC25A12,NDUFA4,CYCS,COX4I1,SDHA,NDUFS7,NDUFS4,FASTKD3,NDUFV1,NDUFA2,NDUFB4,CS,SUCLG2,NDUFB9,NDUFS8,CYC1,NDUFA3,IDH3A,TBRG4,OGDH,NDUFA7,NDUFB1,POLG2,TAZ,CAT,SDHB,COX7A2L,NDUFA11,COX8A,DHTKD1,COX5A,UQCRH,MDH1,NDUFS5,IDH3B |
| 5.260e-08 | -16.76 | MODULE_257 | MSigDB lists | MODULE_257 | 150 | 49 | 17377 | 2626 |
KIAA0100,TSC2,RAB11B,ZDHHC8,PIGQ,MDH2,VAV2,DLGAP4,ARFIP2,TGOLN2,TAF6L,CCNL2,SLC20A1,SRRT,EDC3,USP5,RTKN,GNS,APLP2,SHC1,HDAC7,RAB35,MTA1,SSBP3,TNPO2,GLE1,N4BP2,TELO2,ERF,AKT2,OXR1,LRRC8A,ANAPC2,LRP5,MEF2D,PTTG1IP,SNRPA,CHAF1A,DDX17,YIF1A,PLD3,SEC61A1,DGCR8,LIMK1,NAGLU,OAZ2,SH3GLB2,IMPDH1,SNRNP70 |
| 5.297e-08 | -16.75 | GO_GOLGI_APPARATUS_PART | MSigDB lists | GO_GOLGI_APPARATUS_PART | 846 | 185 | 17377 | 2626 |
RAB14,TMED7,COPA,GXYLT1,AGRN,ADAM10,TGOLN2,CDIPT,SEC16A,BECN1,SYNRG,RAB8A,ASAP2,CDC42,RAB35,AP1M1,DNM2,AP2B1,TFG,RHBDD2,MGAT5,PLK3,PGAP2,USO1,RHOBTB3,TMEM115,NRAS,NCK1,LAP3,APH1A,ATG9A,PITPNB,GALNT7,MCFD2,STX16,SLC50A1,RAB2B,RHEB,OPTN,MAN2A2,TMED10,MYO18A,ST3GAL2,ROCK1,GALNT10,CLN3,CHPT1,CHPF2,RTN3,NAA60,B4GALT2,SVIP,SCOC,GORASP1,AGTRAP,HLA-E,SDC2,PCSK7,B4GALT1,TMED3,RAB6A,SLC35B1,NOTCH2,B4GALT4,PSEN1,TMEM165,QSOX2,COPG2,COPB2,CD59,RNF121,C1GALT1,PPIL2,TPST1,PIKFYVE,LPCAT1,PPP6R1,TMED2,KDELR1,PREB,NAGPA,GCC2,CYTH1,TRAPPC9,MFNG,GORASP2,GOSR1,ZDHHC3,SEC31A,GNAS,GOLGA4,GALNT2,GOLGA2,NSF,ARAP1,VCPIP1,ZDHHC7,SMPD4,PPP6R3,CORO7,SYS1,GNPNAT1,TRIP10,SLC2A1,COPE,RAC1,GPR89A,VTI1A,SLC39A13,SLC35B2,AP1B1,EXT2,BCAP31,APP,ANKRD28,RAB21,PPP6C,NSFL1C,CLTB,LMAN1,GCC1,EBAG9,CLCN3,GOPC,CUL3,PKMYT1,RAB1A,AP4E1,ERC1,SURF4,SCAP,GOLGA8A,CANT1,AP1S1,ATF6,B4GALT3,CHID1,CSNK1D,GOLIM4,GOLPH3L,TMBIM4,SCAMP3,B4GALT5,SRGN,SCYL1,VPS45,ARFIP2,CHIC2,AGPAT3,ARF1,GGA2,RAB11A,HLA-A,SPPL2A,MAN1A1,PDCD10,KLHL20,SEC24C,FUT8,SLC35B4,ZDHHC13,ST8SIA2,SLC35A1,MOB4,B3GALT6,TGFB1,ATP2C1,COG1,RFFL,PACS1,PNPLA8,SPPL2B,SH3GLB1,YIF1A,HLA-B,NUCB1,SEC23IP,GOLGA7,SNAP29,WNT5B,STX18,GLG1,HRAS,GPR89B,SNAPIN |
| 5.325e-08 | -16.75 | C1QBP (complement C1q binding protein) | protein interactions | 708 | 235 | 71 | 17029 | 2761 |
CYLD,LYRM4,SUZ12,CUL1,MRPL19,GRSF1,NUP107,MRPS27,TARDBP,NUP153,AHCYL1,PDIA6,DVL2,FYTTD1,ZNF524,EXOSC6,COQ10B,LYRM1,MRPL12,LACTB,CUL3,SREK1,ABHD11,MCM2,CBFB,LUC7L,SRSF1,BOLA3,DAP3,COPS6,RRS1,ARRB2,MAPK1,COIL,RPS2,PHB2,MRPS2,HABP4,TCF3,MRPS26,CHCHD2,RPL15,ADCK5,NDUFA4,FAM136A,XPNPEP3,LYRM2,HUWE1,YBX1,MRPL21,FBL,EEF1D,LUC7L2,PRRC2A,TUFM,MRPS10,ADRB2,TOMM40,MAPK3,CAND1,XRCC5,GNAS,MAGED2,SGSH,LRPPRC,ATP5F1A,PSAP,WDR76,PREPL,MRPL3,CDKN2A |
| 5.481e-08 | -16.72 | CNBP (CCHC-type zinc finger nucleic acid binding protein) | protein interactions | 7555 | 141 | 49 | 17029 | 2761 |
HNRNPAB,NOP2,RPLP2,SUZ12,DHX9,RPL15,EBNA1BP2,BRIX1,MAPK14,TTF1,BZW2,PABPC4,ZNF275,RPL11,RPL23A,ERH,RBM34,RPF2,DDX31,ZNF800,FTSJ3,PCBP2,NOL12,STAU1,DDX24,ZNF512,GTPBP4,RPL8,RPL6,LLPH,CADM1,MAK16,CENPU,RPL36,NSA2,DAP3,SYNCRIP,RPL32,HNRNPR,NIP7,ZNF689,RBMX,RPLP1,RRS1,CDK2,PURA,NMD3,ZC3HAV1,CCDC137 |
| 5.481e-08 | -16.72 | PHB (prohibitin) | protein interactions | 5245 | 141 | 49 | 17029 | 2761 |
CYLD,PHB2,SUZ12,RAF1,OLA1,SMARCA4,COX4I1,ATP5F1B,RAB11A,BCAP31,LMNA,SSR1,RB1,BABAM2,NDUFB4,HUWE1,ZNF746,CAPZA1,BCAP29,TAGLN2,CYC1,LMAN1,ATF2,MTX2,FGFR1OP2,STAU1,LONRF3,RAB7A,CUL3,VDAC2,KRAS,ADRB2,PLEC,VDAC1,RAB1A,SLC25A5,STOML2,AKAP1,NAP1L1,ATP1A1,SYNCRIP,DDOST,RBL1,E2F1,ACTB,YWHAZ,FUS,CLN3,CDK2 |
| 5.535e-08 | -16.71 | RPL32 (ribosomal protein L32) | protein interactions | 6161 | 113 | 42 | 17029 | 2761 |
RPS15,COX15,RPS2,CYLD,MECP2,DHX8,RPL15,CUL1,NENF,RBM4,RPL11,RPL23A,RPL17,RBM34,RPL19,TARDBP,ZC3H3,RPL29,ZNF512,RPL8,ILF3,TUFM,RPL6,LSM8,PRPF3,BRCA1,MCM2,RPL27A,KIF11,MAK16,RPS9,RPSA,CAND1,RPS14,DUSP11,PRPF4,RRS1,FAU,CDK2,RPS26,ZC3HAV1,GPATCH4 |
| 5.535e-08 | -16.71 | SRSF7 (serine and arginine rich splicing factor 7) | protein interactions | 6432 | 113 | 42 | 17029 | 2761 |
SART1,MZT1,EWSR1,SUZ12,SRSF6,EIF3D,DHX9,CUL1,USP39,CCNL2,EIF4A3,BUD31,MSH2,TRA2B,TARDBP,PCBP2,LUC7L2,HP1BP3,CDC5L,SRPK2,SRSF11,STAU1,SF3B6,HNRNPF,RNPS1,SREK1,PRPF3,SRSF5,SEPT7,CDK11A,SF3A2,DHX15,SRSF1,CAND1,SURF4,CLK3,LUC7L3,SAFB,DUSP11,ZRANB2,SRSF3,CDK2 |
| 5.547e-08 | -16.71 | CENPA (centromere protein A) | protein interactions | 1058 | 90 | 36 | 17029 | 2761 |
H2AFZ,HJURP,ZFP91,KIF23,SRRT,MRPL19,RRP36,OIP5,TBC1D14,MRPS27,H2AFY,MRPL54,CENPM,FBL,COPS8,PRKDC,NOL8,AURKB,SHCBP1,CENPU,RPA1,CBX3,SUPT16H,DDX17,XRCC5,H2AFX,ACTB,DDX5,RUVBL2,CENPT,H3F3A,MRPL3,CDKN2A,DDB1,PDF,SSRP1 |
| 5.587e-08 | -16.70 | PTBP1 (polypyrimidine tract binding protein 1) | protein interactions | 5725 | 137 | 48 | 17029 | 2761 |
COX15,CYLD,HNRNPAB,PHB2,SUZ12,CUL1,ATP5F1B,PRKACA,PCBP1,APP,RAVER2,HNRNPA2B1,RPA2,MDM2,SAR1A,YBX1,TARDBP,PCBP2,SRPK2,CDC5L,SPTAN1,CUL3,TUFM,RANGAP1,BRCA1,SRSF5,MCM2,RAB1A,ABCF1,MATR3,SNRPA,RPSA,ISG15,RPA1,DDX17,CAND1,RPL36,STOML2,EPRS,TIMM13,QARS,ACAT1,FUS,ATP5F1A,FAU,CDK2,ARRB2,HNRNPDL |
| 5.628e-08 | -16.69 | REACTOME_ADAPTIVE_IMMUNE_SYSTEM | MSigDB lists | REACTOME_ADAPTIVE_IMMUNE_SYSTEM | 502 | 121 | 17377 | 2626 |
UBE2E2,TSC2,UBR2,DYNLL1,RAF1,TRIM11,RAC1,TAP1,CUL1,UBE2Z,UBE2Q1,KIF2C,AP1B1,PRKACA,LYN,CALM2,VAV1,RAP1A,MDM2,PSMD1,PSMA6,SHC1,CDC42,PIK3R2,UBA5,AP1M1,DNM2,AP2B1,CDKN1B,KIF22,ANAPC7,TAP2,ASB6,DCTN1,MLST8,SEC61B,NRAS,PSMA8,NCK1,RBX1,AKT2,VHL,RAB7A,RNF25,PSMB7,CUL3,KIF15,CDC23,ASB13,PSMB9,KIF2A,PPP2CA,CDC16,WAS,PPP2R5A,SEC61A1,TAB2,RPS27A,PSMD8,PSMD3,TPP2,ITGB1,AP1S1,TRIM32,SMURF1,PSMC1,AP2S1,DYNC1LI2,UBE2D3,KIF3B,TRIP12,SEC61G,DCTN2,KIF23,KLC1,RACGAP1,AKT1S1,ARF1,UBE4A,ITGB5,PSMD9,FOXO3,HLA-A,FBXO3,KIF5B,PSMD2,VASP,CTSS,UBE2Q2,KLHL20,PTEN,HUWE1,SEC24C,ORAI1,KIFAP3,UBE3B,UBE3C,CREB1,MAP3K14,LRSAM1,UBE2M,PDPK1,PSMA1,ANAPC2,KRAS,ICAM2,KIF11,PSMB3,PSMC4,SEC31A,HLA-B,KEAP1,KIF18A,CDC27,CSK,CTSA,YWHAZ,UBE2C,CD81,HRAS,ANAPC4 |
| 5.659e-08 | -16.69 | SUMO E3 ligases SUMOylate target proteins | REACTOME pathways | R-HSA-3108232 | 104 | 40 | 10287 | 1696 |
NDC1,NSMCE4A,NUP188,RAE1,SUMO2,NUP54,CDCA8,SMC6,TOP2B,BLM,UBE2I,NUP205,PHC2,MDM2,PCNA,SMC3,NUP210,SP100,HDAC7,MTA1,NUP107,NUP153,NUP85,SEH1L,SP3,RANGAP1,NUP155,AURKB,BRCA1,RPA1,BIRC5,NSMCE2,PIAS2,PML,NUP62,XRCC4,NUP58,CBX4,CDKN2A,AAAS |
| 5.696e-08 | -16.68 | GSE5503_LIVER_DC_VS_MLN_DC_ACTIVATED_ALLOGENIC_TCELL_DN | MSigDB lists | GSE5503_LIVER_DC_VS_MLN_DC_ACTIVATED_ALLOGENIC_TCELL_DN | 186 | 57 | 17377 | 2626 |
WSB2,DDX58,RHOG,PPCS,CKLF,PHF23,RAF1,DLGAP4,C5orf30,KLC1,SIKE1,CREBL2,MAN2B1,EZH1,IL21R,MIEN1,ANKRD39,KIAA1147,TMCC3,SEC11A,THADA,PHTF1,RCSD1,BDH1,MAVS,TP53BP2,CNN2,GTF2H2,MRPL32,FDFT1,CSNK1G2,ZNF672,ADAM17,MKLN1,NCK1,TLK1,MRS2,TEX10,RABIF,BCLAF1,PRMT2,GOSR1,NDRG3,PATL1,PICALM,YIF1A,TMEM127,SPATA2,CSNK1G1,ARNTL,TBPL1,CAB39,TCOF1,MAP3K5,FAM208A,HIGD2A,RNF114 |
| 5.696e-08 | -16.68 | GSE28726_ACT_CD4_TCELL_VS_ACT_NKTCELL_DN | MSigDB lists | GSE28726_ACT_CD4_TCELL_VS_ACT_NKTCELL_DN | 186 | 57 | 17377 | 2626 |
CYLD,PNISR,TSC2,HLA-E,SRSF6,SRGN,UBXN1,DNAJB1,CDIPT,RGS2,PRPF18,RGS1,MOAP1,ZNF428,ADD3,KDM2A,IL6ST,NSFL1C,JOSD1,ATG13,AFF1,ATP6V1G1,PLK3,CYTH1,RPL29,TNFAIP3,BTG2,KAT7,TLK1,RPS10,RPL38,CIRBP,EZR,BCLAF1,NFATC2IP,SRSF5,OGFR,KDM3A,RBM38,EIF3A,PPP2CA,TRAM2,JAK1,CHD3,GPS2,AXIN1,HNRNPH3,CCDC69,RBMS1,DDX5,NCOA1,SNRNP70,H3F3A,CLN3,RNF139,TERF1,TOB1 |
| 5.703e-08 | -16.68 | SH3GLB1 (SH3 domain containing GRB2 like, endophilin B1) | protein interactions | 51100 | 79 | 33 | 17029 | 2761 |
USP7,SARNP,ACTR3,GADD45G,AGFG1,XPO7,UBE2I,PRKACA,SCYL2,APP,CDK5,RPA2,FLAD1,SUB1,MTA1,DNM2,SEPT11,ARHGAP17,RPRD1A,LAP3,NSUN2,HTATIP2,PSMA1,GORASP2,RANGAP1,SEPT7,ARPC1A,SH3GLB1,TPD52L2,HSPBP1,VPS26C,SH3GLB2,ADAM9 |
| 5.731e-08 | -16.67 | MRPL4 (mitochondrial ribosomal protein L4) | protein interactions | 51073 | 125 | 45 | 17029 | 2761 |
RMND5A,RPS2,MRPL9,CYLD,MRPL42,GNPNAT1,MRPL39,CSNK2A1,MRPL19,MRPL50,PCNA,RPL17,GRSF1,MRPL34,CYC1,MRPL40,MRPL48,MRPL21,MRPL11,MRM3,MRPL32,MRPL57,HTRA2,GID8,DDX28,EXOSC6,MKLN1,DDX24,MRPL12,MRPL43,CUL3,RPL8,ILF3,TUFM,MRPL16,ARMC8,CAND1,MRPL2,MRPL55,HNRNPR,TATDN2,MRPL27,DUSP11,MRPL13,MRPL3 |
| 5.731e-08 | -16.67 | GO_CATABOLIC_PROCESS | MSigDB lists | GO_CATABOLIC_PROCESS | 1705 | 335 | 17377 | 2626 |
PDCD6IP,TMEM203,HEXB,CUL1,GLUD1,GYG1,CCNB1,OAT,UBE2I,PARK7,PABPC4,FBXO22,RPL23A,CALM2,CDK5,PSMD1,DNAAF2,RAD23B,CISD2,PCBP2,USP34,ATG9A,TOPORS,AURKB,AMDHD2,USP22,CCNF,RPS27A,PSMD8,PTER,AXIN1,RPS14,PRDX5,DHTKD1,ATE1,MLYCD,SMG9,FBXL3,ARRB2,LONP2,PFKP,MUT,MRPS2,DHPS,ADO,GSPT2,KCTD17,MAN2B1,ZNRF3,PSMD9,PARN,VPS25,NPLOC4,CNOT3,ATG4A,GNS,RNF121,PDXP,EXOSC7,MEX3C,RIMS3,BDH1,FBXO7,FBXL7,PHKG2,PABPC1,MAN1B1,RPS10,RPS24,USP10,EXOSC9,MPG,PATL1,PSMB3,PI4K2A,DERL1,CAT,KPNA1,USP32,CNOT6,MDH1,SMPD4,GPI,WIPI2,RNF14,HEXA,RNF139,CDKN2A,NUDT3,ATXN3,TRERF1,UBR2,PTTG1,ADPGK,ANKIB1,NUDT19,DECR1,SIAH1,UCHL5,DUT,MTA1,LPIN2,NSFL1C,SOCS6,ANAPC7,TTC3,RNF19A,C8orf59,RNASEH2A,CLN6,GPD1L,ENPP4,SEC61B,CUL3,RNPS1,POLR2D,RPL38,CRNKL1,PFKFB3,CDC23,PSMB9,PPP2CA,ANKZF1,ALDH3B1,CDC16,HINT1,LSM6,SEL1L,RPLP1,RNF38,TRIM32,USP13,GALK1,RPS2,MANBA,ATG2B,SDF2L1,UBE4A,NEIL2,WWP2,CAPN2,RFWD3,PSMD2,PTEN,RPL17,HUWE1,CRAT,PPP1R8,FUT8,DCP1A,GTSE1,ANXA5,UPF2,RPL19,UBE3B,CNOT6L,FBXL19,LYPLA2,IMPA2,TNFAIP3,RNASEH2C,GALC,USP42,RPL8,LDHA,MRPS10,FBXO9,ANAPC2,RPL27A,PDE3B,MARK2,ECH1,PRDX1,SH3GLB1,FBXO21,PLD3,SGSH,KEAP1,RPL32,PRDX3,TATDN2,ACOX1,PML,KHSRP,HMGB2,YWHAH,FAF1,ANAPC4,DDB1,AGRN,GNPDA1,RBM8A,MCCC1,UBE2Z,SIRT2,UBQLN2,USP48,BECN1,BIRC2,RNF103,BCAT2,MBD4,EDC3,PCYOX1L,EIF4A3,GOT2,ATG3,SLC44A1,HADHB,TXLNA,NDUFB9,OGG1,CDC37,PLK1,EXOSC6,RBX1,SNRPB,LRP5,USP21,RPL37,NAGLU,CHEK2,VPS4A,CLN3,NGLY1,PSMC1,RPS26,CAPN1,UBE2D3,RPS15,TMUB1,DNAJB2,UBXN1,SDC2,RPL15,THRAP3,EPHX2,RHBDD1,PRPF18,DTL,SLC27A4,AHCY,UBE3C,ACAD8,ZRANB1,LRSAM1,ZNF189,ABHD2,ERLIN1,GBA,RPL6,PSMA1,SYVN1,UBE4B,ISG15,RPL36,PSMC4,CDC27,KLHL15,SIAH2,DTD1,CTSA,USP7,CYLD,RPLP2,PAIP1,USP5,RPL11,RAD23A,CSDE1,UBXN2A,PSMA6,MDM2,KIF14,EXOSC1,HTRA2,GM2A,RLIM,PRPF19,SNX25,RPL29,RPL35,POLR2G,PPT1,PSMA8,RAB7A,PSMB7,OGDH,EDEM2,RPS9,USP36,RPSA,PON2,DNAJC10,IDE,UBXN2B,PSMD3,ARNTL,UHRF2,CHMP4B,SCARB1,USP11,FAU,SMURF1,LTA4H,CHID1,TRIP12,KLHL21,CSNK1A1,DNAJB9,HERC3,CTSS,KLHL20,SLC1A4,PELO,ATG13,ABCD1,RNF5,TGFB1,TMEM39A,RFFL,PNPLA8,HAGH,NEU1,UPF1,CTBS,COX8A,USP20,ACAT1,ACADM,TATDN1,PGAM1,UBE2C,SAT2,GCSH |
| 5.742e-08 | -16.67 | GSE25088_CTRL_VS_ROSIGLITAZONE_STIM_STAT6_KO_MACROPHAGE_DN | MSigDB lists | GSE25088_CTRL_VS_ROSIGLITAZONE_STIM_STAT6_KO_MACROPHAGE_DN | 177 | 55 | 17377 | 2626 |
MIF,C1orf74,PPP1R37,H2AFZ,HJURP,PHRF1,HMGXB3,POC1A,RRAGC,SNN,MYEF2,CPNE3,RRP36,LRRC14,FBRS,ABL2,GSTK1,ATP6V0B,CTSS,CBWD2,RAB35,PPP1R12C,MRPL34,ZDHHC13,DDX31,TAF5L,MAVS,UBE3B,TMEM9,GM2A,MED22,TACC3,CSNK1G2,TIMM8B,NEK7,MTA2,NOL8,LDB1,TUBGCP5,ZNF574,SLC25A22,MAP7D1,ICMT,PSMB9,BSDC1,SPATA2,NDUFA11,DNAJC17,PSAP,WIPI2,AKNA,TAF6,E2F2,CCDC59,SSSCA1 |
| 5.742e-08 | -16.67 | GSE32533_WT_VS_MIR17_OVEREXPRESS_ACT_CD4_TCELL_UP | MSigDB lists | GSE32533_WT_VS_MIR17_OVEREXPRESS_ACT_CD4_TCELL_UP | 177 | 55 | 17377 | 2626 |
RRP15,POLR2K,RPS6KA1,HABP4,CSNK2A1,NIPA2,GLUD1,SLC29A1,GLRX3,IL21R,BZW2,RAB21,MDM2,SUV39H2,EIF4A3,PTEN,CD3EAP,ORAI1,PARL,POLR1B,AHCYL1,CPSF4,CNPY3,STRAP,FTSJ3,ABCC1,NUDC,ANKLE2,STAU1,DDX28,AATF,ELL2,ZNF574,UTP15,ILF3,TMEM147,PRKRA,RHOB,TMEM201,CLNS1A,PHF6,ZNF317,GALNT2,CCDC6,TIMM17A,CDCA7L,SEL1L,ACAT1,BEND3,TMEM101,CD81,CCDC59,MRPL3,GPATCH4,GEMIN7 |
| 5.758e-08 | -16.67 | ABRAMSON_INTERACT_WITH_AIRE | MSigDB lists | ABRAMSON_INTERACT_WITH_AIRE | 44 | 22 | 17377 | 2626 |
NASP,PRKDC,SNRPB,SNRPD3,MCM2,TRIM28,POLR2A,CAND1,SRSF1,DDX17,SUPT16H,GEMIN5,SMC3,PCNA,MCM5,EFTUD2,MSH2,DDX5,SRSF3,RUVBL2,PABPC1,MSH6 |
| 5.934e-08 | -16.64 | purine ribonucleotide binding | molecular function | GO:0032555 | 1840 | 363 | 17224 | 2647 |
RAB14,ABCC10,TAP1,DHX8,GLUD1,UBE2I,EEF2K,KIFC1,CDK5,NEK6,RAB4A,ATP13A3,PDS5B,DNM2,UPRT,SUCLG2,MAST2,PLK3,RHOBTB3,NRAS,AKT2,PBK,KIF15,MKI67,DDX20,SMC2,AURKB,MCM2,RFC2,RAB22A,RAB2B,ARF4,MAP3K4,MKNK1,KIF18B,LIMK1,MYO18A,RNASEL,LONP2,PFKP,DDX42,DDX58,HSPH1,RECQL,CHTF18,RHOC,TRIO,GSPT2,PRKAA1,DHX9,RRM1,RAB23,CERK,KIF23,TOP2B,EIF2AK4,RTKN,DDX56,SMC3,MCM5,EFTUD2,CTPS1,MSH2,DAPK1,RTCB,PIKFYVE,GNAI2,PHKG2,UBE2QL1,CARS2,DDX28,COQ8A,MAPKAPK3,DHX29,NOA1,PGS1,GTPBP4,PIP4K2C,SEPT8,RIT1,PKM,ABCF1,MAP2K2,CCT8,RHOB,PI4K2A,XRCC5,ADSS,EPRS,NSF,CSK,CSNK1G1,DCK,QARS,ACLY,MAP3K5,CDK2,NRBP1,ACSF2,RHOG,KARS,ABCA3,TP53RK,RAB11B,RPS6KA1,RAF1,CHD1L,KIAA0232,ACTR3,RAC1,OLA1,TPX2,MYH9,EFL1,PRKACA,CBWD5,FLAD1,RAB21,PRKD3,ATP2A2,RALB,UBA5,ADCY9,CLCN6,SEPT11,TAP2,AQR,ARL5A,CDK12,ADCY7,CCT2,ULK3,ATP13A1,MAP4K4,TAOK1,PFKFB3,GALK2,PKMYT1,DNAJA1,RAB1A,MAT2A,DHX57,DDX17,KIF2A,RAD51C,HSPA4,JAK1,RAB24,GUCY1B1,HIPK2,CBWD1,PDXK,PPP5C,CSNK1D,TUBB,DYNC1LI2,RHEBL1,PRPF4B,POLQ,GALK1,ANXA6,TWNK,IP6K2,ATP5F1B,BLM,PMVK,IFT27,RAB11A,PIP5K1C,SRXN1,GATC,CBWD2,ARF5,TTLL12,MAP3K14,UBE2M,MSH6,SMC4,PDPK1,TK1,DDX24,GUK1,NEK7,BMS1,RHOT1,DDX39A,GUF1,KIF11,MARK2,MYO1F,GNA12,KIF18A,TTLL4,MAPK6,ASNA1,DDX5,DDX52,DDX47,UBE2E2,YTHDC2,MCCC1,CSNK2A1,UBE2Q1,UBE2Z,ABCB10,KIF2C,MAPK14,PAPOLA,ABL2,RAB8A,RAP1A,CDC42,EIF4A3,RAB35,TRMU,XRCC2,KIF22,RP2,EIF5,ABCC5,SRPK2,PLK1,LARS,SNRNP200,SEPT9,HARS,TLK1,CDC6,RAB5B,LSG1,STK17B,DHX15,RHEB,SEPT1,CHD3,IARS2,BAZ1B,QRSL1,ACTB,STK11,CHEK2,VPS4A,ROCK1,PSMC1,SEPHS2,UBE2D3,CDK13,THRAP3,RAB6A,CHKA,UBE2Q2,KIF13B,ALDH18A1,N4BP2,CSNK1G3,ABCC1,NTPCR,AACS,ACSL3,MAP4K3,EIF2AK1,KRAS,UBE4B,SEPT7,DAPK3,BBS12,MASTL,PSMC4,GNAS,PRPS2,NLRC5,RUVBL2,ATP5F1A,MYO9A,EHD4,PMS2,UCK2,SMARCA4,RRAGC,UCK1,CHKB,ORC1,ATP6V1B2,LYN,TWF2,CHD1,MIEF1,FARSA,PDK2,IARS,SAR1A,NVL,KIF14,SCYL3,ACSL5,CLCN3,CGAS,RAB7A,ARL5B,RAD54B,DAP3,ATP1A1,IDE,DHX16,CLK3,STK38,FASTK,XRCC3,MAPK1,ABCA1,RAD51D,KIF3B,NADSYN1,SHPRH,TOR3A,GNE,SCYL1,SMC6,ARFIP2,ARF1,MYO9B,CDK11B,CSNK1A1,SCYL2,PIP4K2A,GFM2,WRNIP1,KIF5B,GTPBP3,STARD9,FGFR3,GART,GRK2,ABCD1,DDX31,CAMK2G,MYO5A,CSNK1G2,RHOA,PRKDC,HELB,BTAF1,ATP2C1,ABCF2,TUFM,PRKAR1B,NADK2,PNPLA8,RHOT2,CDK11A,TARS,MAPK3,DDX23,HSPA1B,MFN2,RAB18,NEK1,UPF1,ATAD2,UBE2C,RPS6KC1,HRAS,HIPK3 |
| 6.008e-08 | -16.63 | SEC24A (SEC24 homolog A, COPII coat complex component) | protein interactions | 10802 | 58 | 27 | 17029 | 2761 |
SEPHS2,UNK,EWSR1,CUL3,JMJD6,MAN2B1,SEC16A,CLNS1A,CYHR1,PSMD2,PSMD1,THADA,STAT6,SEC24C,UBXN2B,PRDX5,TTC9C,PTAR1,GTSE1,TFG,AHCYL1,UBE2C,IGBP1,S100A6,TACC3,SSSCA1,USP34 |
| 6.048e-08 | -16.62 | signal transduction involved in DNA integrity checkpoint | biological process | GO:0072401 | 76 | 31 | 17256 | 2622 |
PLK3,PLK1,PRKDC,BTG2,BABAM1,BRCA1,CCNB1,SOX4,CNOT11,CNOT3,CNOT9,DTL,BABAM2,PCNA,MDM2,RPS27A,CENPJ,E2F4,TFDP1,E2F1,PML,CDKN1B,GTSE1,CNOT6,CHEK2,TFDP2,CNOT6L,CDK2,CARM1,CDC5L,PRPF19 |
| 6.048e-08 | -16.62 | signal transduction involved in DNA damage checkpoint | biological process | GO:0072422 | 76 | 31 | 17256 | 2622 |
PLK3,PLK1,PRKDC,BTG2,BABAM1,BRCA1,CCNB1,SOX4,CNOT11,CNOT3,CNOT9,DTL,BABAM2,PCNA,MDM2,RPS27A,CENPJ,E2F4,TFDP1,E2F1,PML,CDKN1B,GTSE1,CNOT6,CHEK2,TFDP2,CNOT6L,CDK2,CARM1,CDC5L,PRPF19 |
| 6.077e-08 | -16.62 | GSE19941_IL10_KO_VS_IL10_KO_AND_NFKBP50_KO_LPS_AND_IL10_STIM_MACROPHAGE_DN | MSigDB lists | GSE19941_IL10_KO_VS_IL10_KO_AND_NFKBP50_KO_LPS_AND_IL10_STIM_MACROPHAGE_DN | 155 | 50 | 17377 | 2626 |
EXOC3,IMMT,GMCL1,NUF2,KIF2C,REEP5,SDHA,CPNE3,NUP205,COPB2,MEAF6,FBXO22,PAPOLA,SF3B2,DTL,RFWD3,ERH,PSMD1,ATP2A2,NUP107,PTPN11,PRC1,SEPT11,TTC3,ZRANB1,LPCAT1,DNMT1,ARL5A,TACC3,PHF20L1,AKT2,ANAPC2,PRPF3,PBRM1,ESYT1,GALNT7,MCM2,VDAC1,CYFIP2,HMGN2,RAB18,CDC27,DGCR8,SNAP29,CORO1C,CBLN2,SLC16A1,MAP3K5,SMURF1,SSRP1 |
| 6.205e-08 | -16.60 | LEE_EARLY_T_LYMPHOCYTE_UP | MSigDB lists | LEE_EARLY_T_LYMPHOCYTE_UP | 96 | 36 | 17377 | 2626 |
MCM10,PTTG1,CDCA3,NUF2,KIF2C,CCNB1,NCAPG,FANCI,OIP5,DTL,SLC1A4,KIF14,PRC1,GINS1,ASPM,RAD51AP1,PBK,KIF15,MKI67,RRM2,CDCA2,NUSAP1,GALNT7,MCM2,KIF11,ATAD2,KIF18B,BIRC5,NEIL3,CEP55,RUFY3,TFDP2,CCNB2,E2F2,UBE2C,TUBB |
| 6.205e-08 | -16.60 | DING_LUNG_CANCER_EXPRESSION_BY_COPY_NUMBER | MSigDB lists | DING_LUNG_CANCER_EXPRESSION_BY_COPY_NUMBER | 96 | 36 | 17377 | 2626 |
DNAJC2,CMAS,PPP1R12A,THOC1,RAE1,CBLL1,MYNN,GTF3A,CDC42SE2,FBXO3,NAPG,ZNF302,H2AFY,NUP153,TXNL1,RB1CC1,GABPA,E2F3,MTMR6,DCTD,FXR1,ARMC8,EIF3H,ANKRD46,KRIT1,ANKRD10,TAF2,PDCD6,SEC23IP,KPNA4,GOLGA7,BRWD1,SNAP29,CEBPG,SIAH2,TERF1 |
| 6.248e-08 | -16.59 | GSE34392_ST2_KO_VS_WT_DAY8_LCMV_EFFECTOR_CD8_TCELL_UP | MSigDB lists | GSE34392_ST2_KO_VS_WT_DAY8_LCMV_EFFECTOR_CD8_TCELL_UP | 191 | 58 | 17377 | 2626 |
TCF12,SNX27,CORO7,HJURP,RPS6KA1,KIF23,SMC6,GYG1,NOTCH2,IKBIP,DOCK11,DUSP22,FOXO3,FBXO5,EEF2K,STARD9,ADD3,DPYSL2,PHF14,SOCS6,CNPY4,ANP32A,PIKFYVE,GPD1L,CTDSP2,TPCN1,TRIM14,CAMK2G,KDELR1,PDLIM2,HP1BP3,SRPK2,PDPK1,RPL35,PPT1,MBLAC2,TUBGCP5,SLBP,ESYT1,LRRC1,VDAC1,SLC50A1,EIF3H,POLR2A,ECH1,MAN2A2,OSBPL11,TXNDC16,DHX16,CDCA7L,PRPS2,MRFAP1L1,PDXK,NCOA1,EHD4,NANP,CBX4,PDCD4 |
| 6.248e-08 | -16.59 | GSE26343_WT_VS_NFAT5_KO_MACROPHAGE_UP | MSigDB lists | GSE26343_WT_VS_NFAT5_KO_MACROPHAGE_UP | 191 | 58 | 17377 | 2626 |
SEPHS2,MANBA,WDR13,ZFP91,ANKH,GNE,TMX4,UCK2,KIF23,C19orf48,TMEM165,RFWD3,CDKN2C,ZBTB45,NFATC3,DPYSL2,DDX31,ZNF710,LDLRAD3,DNMT1,FTSJ3,MSH6,RNF169,KDELR1,NIPAL3,POLR2I,SEPT9,POLK,SIGMAR1,NET1,EMB,SELPLG,DENND4C,METTL5,MRPL12,ADSL,SLBP,NFATC2,GALK2,CBX3,MTMR3,MAN2A2,MRPL2,TXNDC16,PRPS2,APPL2,ZFP90,ACADM,NCOA1,RNASEL,DMWD,REEP4,CDK2,NAA60,ZMAT3,RAB3IL1,NUDT3,PRPF4B |
| 6.365e-08 | -16.57 | GSE2770_IL12_ACT_VS_ACT_CD4_TCELL_48H_DN | MSigDB lists | GSE2770_IL12_ACT_VS_ACT_CD4_TCELL_48H_DN | 182 | 56 | 17377 | 2626 |
MIF,DDX47,MAX,MZT1,ST13,URB2,C16orf87,TMX4,CDCA3,NUP54,TOP2B,NUF2,SLC29A1,PPP3CB,AP1B1,HAUS2,COPG2,KTN1,SLC25A37,FASTKD3,HNRNPA2B1,CLUAP1,PTEN,SIAH1,GMEB1,ZCCHC2,NAA50,CS,KIF22,CORO1A,POLR1B,MTPN,CCT2,VHL,PPP1R21,PPIE,TMEM216,KCTD20,EZR,KRAS,NFATC2IP,PDHX,IRF5,TWISTNB,MTMR3,SGSH,KPNA4,PCM1,RBL1,DNAJC17,FAU,ZMIZ1,CDK2,BRD9,RHEBL1,ADNP2 |
| 6.365e-08 | -16.57 | GSE40274_CTRL_VS_FOXP3_AND_HELIOS_TRANSDUCED_ACTIVATED_CD4_TCELL_DN | MSigDB lists | GSE40274_CTRL_VS_FOXP3_AND_HELIOS_TRANSDUCED_ACTIVATED_CD4_TCELL_DN | 182 | 56 | 17377 | 2626 |
TMEM184B,FAM129A,UCK2,TM9SF3,TMED3,POMP,NANS,SND1,IKBIP,S1PR2,DUSP22,TCF19,TMEM165,CDKN2C,IRF4,ATP2A2,VMP1,GOT2,DAD1,DUT,UBA5,YIF1B,OSTC,TTLL12,TFG,PDIA6,SLC12A2,ARL5A,IMPA2,ALDH9A1,GINS1,CLPTM1,PHF10,USO1,ZFP64,ELL2,TMEM39A,NUDT4,NSDHL,SCFD2,ANLN,KIF11,ALG3,DNAJC10,SEC61A1,MAGT1,DDOST,DBI,FTSJ1,SEL1L,AP1S1,ATF6,COPS6,PLOD3,CHID1,STARD3NL |
| 6.406e-08 | -16.56 | USP37 (ubiquitin specific peptidase 37) | protein interactions | 57695 | 98 | 38 | 17029 | 2761 |
MAX,H2AFZ,MCM10,CHERP,CDT1,CUL1,CCNB1,WRNIP1,RPA2,SMC3,CCNA2,EFTUD2,ZNF326,INTS12,ANAPC7,PRPF19,PLK1,SNRNP200,PRIM2,SUGP2,RNPS1,WDHD1,WDR82,EXOSC9,BRCA1,CDC23,DHX15,ECH1,CBX3,RPA1,TRIM4,CDC16,CDC27,CDK2,TAF6,FAM208A,HDAC2,ANAPC4 |
| 6.418e-08 | -16.56 | AHCYL1 (adenosylhomocysteinase like 1) | protein interactions | 10768 | 154 | 52 | 17029 | 2761 |
PDCD6IP,TXN,POC1A,UFC1,SUMO2,UBXN1,TKT,LAGE3,DHX8,ATP6V1B2,SPR,STMN1,PSMD9,STAM,PIP4K2A,WDR48,SRXN1,CDKN2C,SP100,THADA,SEC24C,TTC9C,ANP32A,TARDBP,AHCY,FBXL7,TAGLN2,PTGES3,AHCYL1,TTLL12,ZC3H3,TACC3,CDC37,USP34,SRPK2,UBQLN4,ABCF2,USP42,UBE2V1,UBE4B,SNRPA,GINS4,SRSF1,PPP2CA,TPD52L2,HGS,STAT6,PPM1G,ANP32E,ZRANB2,ARRB2,UBE2C |
| 6.418e-08 | -16.56 | TRA2A (transformer 2 alpha homolog) | protein interactions | 29896 | 154 | 52 | 17029 | 2761 |
EWSR1,MRPS2,MRPS15,ZNF768,TWNK,SUZ12,SRSF6,CDK2AP2,MRPS26,THRAP3,SRRT,PAIP1,PABPC4,EIF4A3,PPIG,BUD31,MRPS27,MRPL34,TRA2B,PABPC1,MRPL32,LUC7L2,HNRNPM,SRSF10,HP1BP3,SRPK2,CDC5L,YTHDC1,NOA1,SF3B6,RPL6,CUL3,MRPS10,PRPF3,SRSF5,PLEC,SEPT7,GAR1,LUC7L,MRPS14,DHX15,ZFR,DAP3,UPF1,RBM25,CLK3,U2SURP,SRSF3,SNRNP70,CDK2,NKAPD1,CSNK1D |
| 6.486e-08 | -16.55 | MORF_CSNK1D | MSigDB lists | MORF_CSNK1D | 69 | 29 | 17377 | 2626 |
TSTA3,ATG9A,PRKCSH,RAF1,CIB1,AGPAT1,MTX1,RAB1A,PCGF1,BECN1,PARN,SRRT,TUBGCP2,RNF103,POLR2A,MFN2,SLC25A36,TERF2IP,CYHR1,PML,FAM89B,NAP1L4,B4GALT3,STAT3,ZC3H3,NUDT3,DDB1,CSNK1D,MORC3 |
| 6.555e-08 | -16.54 | RPL13 (ribosomal protein L13) | protein interactions | 6137 | 214 | 66 | 17029 | 2761 |
CYLD,CUL1,CSNK2A1,EBNA1BP2,RPL11,RPL23A,MRPL50,EIF4A3,MRPS27,MRPL34,TARDBP,MRPL32,CDC5L,SRPK2,RPL35,RPL38,CUL3,MCM2,RPS9,RPSA,NSA2,ZNF317,MRPL55,RPS14,MRPL27,RPLP1,RRS1,FAU,MRPL13,RPS26,RPS15,MRPL9,RPS2,MRPL42,MECP2,TCF3,RPL15,HUWE1,RPL17,PTEN,AHSA1,RBM34,ZNF746,UPF2,RPL19,MRPL40,MRPL48,PABPC1,NSUN4,TERF2,STAU1,TK1,ZNF512,TEX10,RPL8,ILF3,RPL6,RPS10,MRPL16,RPL27A,CAND1,RPL36,QARS,CD81,CDK2,ZC3HAV1 |
| 6.555e-08 | -16.54 | RPL7 (ribosomal protein L7) | protein interactions | 6129 | 214 | 66 | 17029 | 2761 |
CYLD,NOP2,RPLP2,EBNA1BP2,KIF2C,BRIX1,UBE2I,PABPC4,RPL11,RPL23A,KRR1,PHC2,EIF4A3,TARDBP,RPL35,RPL38,RNPS1,CUL3,BRCA1,MCM2,SLC25A5,RPS9,RPSA,NSA2,HNRNPR,ZNF689,RPS14,MRPL27,RPLP1,RRS1,ARRB2,MRPL13,ZBTB11,RPS26,NIFK,RPS15,RPS2,RPL15,BLM,CDC73,RPA2,RPL17,PTEN,ZNF746,RPL19,FBL,PABPC1,TMX1,HNRNPM,STAU1,DDX24,ILF3,RPL8,TUFM,RPL6,RPS10,RPS24,RPL27A,MATR3,CAND1,RPL36,RPA1,RPL32,CDK2,ZC3HAV1,ZBTB24 |
| 6.673e-08 | -16.52 | GO_MICROTUBULE | MSigDB lists | GO_MICROTUBULE | 380 | 97 | 17377 | 2626 |
ZNF207,SKA3,CYLD,DYNLL1,XIAP,TPX2,SIRT2,KIF2C,MAP1LC3B,STMN1,BIRC2,KIFC1,CALM2,DST,NEK6,WDR44,DPYSL2,MTA1,KIF14,DNM2,KIF22,KCNAB2,DNAL4,DCTN1,PLK1,CCT2,PSRC1,MAPRE2,SEPT9,BIRC3,PBXIP1,CUL3,TUBGCP5,KIF15,NUSAP1,AURKB,EML4,SERP1,KRIT1,KIF2A,MID1IP1,CDC16,KIF18B,AXIN1,MAP4,DVL1,REEP4,DYNC1LI2,CSNK1D,TUBB,KIF3B,HSPH1,MAPRE1,KLHL21,DCTN2,KIF23,KLC1,RACGAP1,HAUS4,RAB11A,TUBGCP2,HAUS2,SPAG5,NEIL2,JAKMIP1,KIF5B,CENPJ,KIF13B,AXIN2,PRC1,GTSE1,ARHGEF2,KIFAP3,KNTC1,NCOA2,MYO5A,NUDC,ASPM,NEK7,PARP4,CAMSAP1,WDR81,KIF11,MACF1,CCT8,MAP2K2,HAUS8,KIF18A,GOLGA2,CDC27,TTLL4,BIRC5,ODF2,LRPPRC,NDE1,IGBP1,BYSL |
| 6.749e-08 | -16.51 | CRMP1 (collapsin response mediator protein 1) | protein interactions | 1400 | 102 | 39 | 17029 | 2761 |
NDUFV2,NAT9,GNE,CDCA8,EPN1,CUL1,JMJD6,PMF1,ATP6V1B2,RGS2,PITHD1,RPA2,EIF2S2,KLHL20,NVL,DPYSL2,PPP1R8,DNAAF2,SEC24C,UBA5,TFG,HDHD2,EEF1D,MOB4,TK1,RHOA,PPT1,LRRC1,FXR1,DPYSL3,FAS,HGS,HSPA4,GOLGA2,AXIN1,HNRNPH3,ROCK1,SNRPG,FUBP1 |
| 6.870e-08 | -16.49 | RPS23 (ribosomal protein S23) | protein interactions | 6228 | 146 | 50 | 17029 | 2761 |
RPS15,RPS2,CYLD,RPLP2,RPL15,CUL1,PNO1,RPL11,RPL23A,MDM2,RPL17,HUWE1,AHSA1,ZNF746,RPL19,TARDBP,HNRNPM,RPL29,RPL35,RPS10,RPL6,ILF3,RPL8,RPL38,TUFM,RPS24,BRCA1,EIF2A,MCM2,RPL27A,SLC25A5,KIF11,RPS9,RPSA,EIF3A,CAND1,RPL36,RPL32,MRPL55,HNRNPR,RPS27A,RPS14,RPLP1,WDR76,FAU,CDK2,ECPAS,CD81,RPS26,DYNC1LI2 |
| 7.003e-08 | -16.47 | GSE5589_UNSTIM_VS_45MIN_LPS_AND_IL6_STIM_MACROPHAGE_UP | MSigDB lists | GSE5589_UNSTIM_VS_45MIN_LPS_AND_IL6_STIM_MACROPHAGE_UP | 187 | 57 | 17377 | 2626 |
TMEM106C,GLT8D1,PNISR,ZCCHC8,GNPDA1,WDYHV1,MRPL39,RPS6KA1,MAGED1,ARID5A,RRM1,FLOT1,MEF2A,NDUFA4,STMN1,BIRC2,HMG20A,RPL23A,PHF14,LPIN2,XPA,MSH2,CDC25B,PIK3IP1,ORC3,RNF135,SLC12A2,MED22,ABCC1,ARHGAP17,ZNF524,CYTH1,MLEC,PPT1,ERLIN1,RDH10,HSDL1,LRP5,PBRM1,WBP1,FXR1,SHCBP1,KLF6,COMMD4,FAS,PFDN5,HSPB11,GALNT2,SURF4,UAP1,SNAP23,NRM,EXOC4,ZFP90,PDXK,AKNA,SNAPIN |
| 7.003e-08 | -16.47 | GSE17721_0.5H_VS_8H_PAM3CSK4_BMDC_UP | MSigDB lists | GSE17721_0.5H_VS_8H_PAM3CSK4_BMDC_UP | 187 | 57 | 17377 | 2626 |
MIF,SLC12A7,NDUFV2,NSMCE4A,DNAJC5,HLA-E,DAP,MDH2,TRIO,KLF13,SUMF1,HAUS4,GLRX3,DECR1,RPN1,INPP5A,AHSA1,BDH1,PDCD2,MARCH2,MRPL48,TALDO1,DNMT1,TMEM160,BAK1,CYTH1,TIMP2,AGGF1,ERMP1,PTPN18,POLR2G,RNASEH2C,PRKDC,RRM2,GALK2,MEF2D,PTTG1IP,HAGH,GINS4,SMAP2,SCARB2,PDCD6,ATP6V1D,HSPBP1,MFAP1,NFIL3,ARNTL,EXOC4,DCAF11,PRMT7,COX5A,MBOAT1,EHD4,ARHGAP23,SMAD4,TOB1,ATMIN |
| 7.065e-08 | -16.47 | LIU_SOX4_TARGETS_DN | MSigDB lists | LIU_SOX4_TARGETS_DN | 291 | 79 | 17377 | 2626 |
RAB14,RAF1,TSC22D3,SMARCA4,CHKB,DAZAP2,MAPK14,ABHD14A,USP5,APLP2,DECR1,SIVA1,MTA1,ETV6,SLC44A1,USP34,ENPP4,SRP72,ANKLE2,RFC3,PGGT1B,CUL3,WBP2,PCGF6,PSMG1,LRP5,BICD2,POLG2,USP21,PLEKHF2,EIF3A,SRSF1,ALKBH6,MAP3K4,MAP4,ATF6,CHEK2,AP2S1,PDCD4,FUBP1,CTDP1,MECP2,DHX9,TRAK1,RGS2,NDUFS7,RPN1,GART,SMC3,PPIL2,FEM1B,UBE3B,UBE3C,ERI3,UBE2M,TMED2,MSH6,MICAL3,TMX1,STAU1,PPP1R9B,LDHA,USP10,BCLAF1,SRSF5,MEN1,CBFA2T2,ARPC1A,MTMR3,EPRS,INF2,PRDX3,DBI,GPI,CDK2,PDLIM5,HIPK3,FAF1,EGLN1 |
| 7.128e-08 | -16.46 | RAB1B (RAB1B, member RAS oncogene family) | protein interactions | 81876 | 87 | 35 | 17029 | 2761 |
RAB11B,RAB6A,ARF1,RAB11A,RIC1,BZW2,APP,CDC73,RPN1,RAB8A,CDC42,AHSA1,DUT,NDUFS8,RPN2,CYC1,TECR,RNF26,MICAL3,TMED2,LDHB,TRAPPC13,RAB7A,VHL,LDHA,RABIF,TOMM40,RAB1A,RAB5B,RAB2B,RAB18,ATP1A1,PDCD6,GOLGA2,SSRP1 |
| 7.130e-08 | -16.46 | nuclear pore | cellular component | GO:0005643 | 82 | 32 | 18223 | 2701 |
NDC1,NUP188,RAE1,NUP54,AGFG1,XPO7,NUP205,AHCTF1,NUP210,SNUPN,NUP107,NUP153,GLE1,MVP,NUP85,SEH1L,EIF5A,NXT1,NUP155,RANGAP1,NUTF2,BICD2,NPIPA1,KPNA1,KPNA4,KPNA2,NUP62,NUP58,IPO4,AAAS,NXT2,TMEM33 |
| 7.177e-08 | -16.45 | DNM1L (dynamin 1 like) | protein interactions | 10059 | 197 | 62 | 17029 | 2761 |
UNK,HSPH1,TXN,HNRNPAB,MDH2,EIF3D,SUMO2,NACA,DCTN2,RBM8A,TKT,JMJD6,ARF1,PARK7,MIEF1,CALM2,CYHR1,ERH,PSMD2,SUB1,EIF4A3,DNAAF2,AHSA1,ATIC,AHCY,TAGLN2,PDIA6,PABPC1,EEF1D,CDC37,LDHB,CDC5L,EIF5A,CCT2,LARS,SF3B6,LDHA,RNPS1,EZR,RRM2,DNAJA1,CCT8,TRIM28,MAT2A,EIF3A,PSMC4,XRCC5,NAP1L1,TIMM13,HSPA4,SAFB,HNRNPH3,CDCA5,ACLY,YWHAZ,RUVBL2,ATP6V1C1,RBBP4,PGAM1,HNRNPDL,PSMC1,ZBTB24 |
| 7.263e-08 | -16.44 | YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_14 | MSigDB lists | YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_14 | 134 | 45 | 17377 | 2626 |
GALK1,DNAJC2,GNPNAT1,GGA1,PIGQ,TMEM97,SMARCA4,PTP4A3,EBNA1BP2,SND1,SNRPD3,SSR1,RB1,RPN1,PSMD1,BANF1,EFTUD2,TANK,CS,TCEA1,FBL,TMEM14C,UBE2M,PPA1,HTRA2,CARM1,SEC61B,HMGN5,NSUN2,MRPL12,MRPS10,SSR2,GORASP2,TMEM147,SLC25A5,ODC1,CCT8,PSMB3,SRSF1,SYNCRIP,SEC61A1,SLAIN1,NDE1,IPO4,PTOV1 |
| 7.461e-08 | -16.41 | MRPL12 (mitochondrial ribosomal protein L12) | protein interactions | 6182 | 163 | 54 | 17029 | 2761 |
RPS2,MRPL9,CYLD,MRPL42,THOC1,RPLP2,MRPL39,MRPS26,CUL1,NIT2,SND1,GFM2,MRPL19,RPL11,MRPL50,MTFR1L,PA2G4,CENPJ,MRPS27,ANXA5,SEPT11,SUCLG2,RPL19,RBM3,TARDBP,CORO1A,MRPL48,MRPL40,MRPL11,TMEM9,MRPL32,MRPL57,MRM2,SEPT9,MRPL12,CUL3,ILF3,TBRG4,SEPT8,EZR,MRPL16,ADRB2,SEPT7,VDAC1,CAND1,C1orf122,MRPL55,ACOX1,MRPL27,GPI,MRPL13,PITRM1,ACSF2,MRPL3 |
| 7.470e-08 | -16.41 | JMJD6 (arginine demethylase and lysine hydroxylase) | protein interactions | 23210 | 130 | 46 | 17029 | 2761 |
KARS,PRPF38B,CHERP,PHRF1,DHX8,ARGLU1,PAWR,CCNL2,XPO7,CDK11B,UBE2I,PIP4K2A,WDR48,GTF2F1,CYHR1,RBM23,NSRP1,PPIG,NAA50,CPSF4,LUC7L2,SRSF11,BRD4,INTS13,USP42,SREK1,CDCA2,DIDO1,LUC7L,CAND1,WAS,HSPA4,UAP1,RBM25,ELMO1,CLK3,MFAP1,TULP3,LUC7L3,PPM1G,U2SURP,STAT1,NKAPD1,PSMC1,VPS29,SSRP1 |
| 7.544e-08 | -16.40 | positive regulation of cellular catabolic process | biological process | GO:0031331 | 339 | 89 | 17256 | 2622 |
ATXN3,TSC2,SUMO2,YTHDF3,SIRT2,UBQLN2,BECN1,BCAP31,ANKIB1,TRIM65,PARK7,FBXO22,EPM2A,USP5,RAD23A,MDM2,RALB,METTL14,RNF19A,CDC37,PLK1,PLK3,TRIM8,POLR2G,RBX1,AKT2,BTG2,PFKFB3,EZR,EDEM2,OPTN,ABHD5,HNRNPR,AXIN1,SOCS4,ADAM9,TICAM1,STK11,CLU,DVL1,ROCK1,SMURF1,PSMC1,CSNK1D,USP13,SVIP,SCOC,AGO2,PRKAA1,NKD2,EIF2AK4,CSNK1A1,PSEN1,METTL3,PIP4K2A,DDRGK1,PTEN,FBXO7,DAPK1,CNOT6L,LRSAM1,TPCN1,PHKG2,PABPC1,SOCS5,ATP5IF1,TNFAIP3,LONRF3,GBA,PIP4K2C,ADRB2,PTTG1IP,SH3GLB1,MAPK3,TFEB,PSMC4,HSPA1B,MFN2,TSC1,KEAP1,UPF1,HSPBP1,KHSRP,CD81,RNF14,TOB1,RNF139,ZC3HAV1,RNF114 |
| 7.546e-08 | -16.40 | carbohydrate derivative metabolic process | biological process | GO:1901135 | 1057 | 223 | 17256 | 2622 |
ADA2,COX15,PIGM,PPCS,GXYLT1,AGRN,NDUFB6,PRKCSH,GNPDA1,UQCR10,PIGQ,HEXB,MOGS,NANS,ATP5PF,PARK7,RNF103,MBD4,CREM,TET3,IMPAD1,PPCDC,AKR1B1,UPRT,NDUFB9,SLC26A2,SLC35C2,MGAT5,OGG1,ABCC5,PGAP2,TMEM115,DPM1,RRM2,AMDHD2,ESYT1,GALNT7,MCFD2,KRTCAP2,STOML2,ALG3,MAN2A2,STT3A,RPS27A,NAGLU,OGT,COX5A,DHTKD1,ST3GAL2,UQCRH,GALNT10,DHFR2,CLN3,CHPF2,NGLY1,NUDT11,PFKP,B4GALT2,NDUFV2,COX5B,PIGN,GORASP1,RRM1,RAB23,CERK,SDC2,ASAH1,B4GALT1,NDUFA4,COX4I1,CYCS,MAN2B1,B4GALT4,PSEN1,TMEM165,NDUFS7,NDUFS4,GNS,RPN1,C1GALT1,NUS1,TIGAR,PYURF,DAD1,ATIC,CTPS1,MSH2,TPST1,PIGG,ATP6V0A2,AHCY,GLTP,CYC1,NAGPA,PIGT,TSTA3,NUDT4,AMD1,MAN1B1,MFNG,USF3,GBA,DCTD,SYVN1,PKM,ADSS,MBIP,GALNT2,UAP1,GOLGA2,DCK,PRPS2,COX7A2L,TYW5,ACLY,TBPL1,CTSA,SMPD4,GPI,ATP5F1A,NANP,NIPSNAP2,HEXA,RNF139,NUDT3,NDUFA5,UGP2,GNPNAT1,UCK2,OLA1,UCK1,RXYLT1,ADPGK,EFL1,SLC35B2,ATP6V1B2,SDHA,EXT2,DUT,ADCY9,RPN2,LMAN1,TALDO1,AHCYL1,GPD1L,CLN6,GM2A,PDCL3,ADCY7,CHP1,ENPP4,PFKFB3,ATP6V0A1,OGDH,NDUFA7,NDUFB1,EDEM2,TAZ,SERP1,DDOST,HINT1,GUCY1B1,NDUFA11,SEL1L,CANT1,B4GALT3,CHID1,GALK1,CMAS,NDUFS1,B4GALT5,MECP2,MANBA,GNE,TRAK1,TKT,SUMF1,ABHD14B,SDF2L1,ATP5F1B,POFUT1,HDDC2,NEIL2,MAN1A1,ERH,NDUFV1,GART,NDUFA2,ITGB8,NDUFB4,FUT8,NDUFS8,OSTC,ST8SIA2,NDUFA3,RNF5,AMPD2,TGFB1,B3GALT6,RHOA,TK1,GUK1,GALC,LDHA,ADSL,ATP5MF,ARSK,PDE3B,NEU1,HSPA1B,SGSH,MAGT1,ATP5MC3,PARG,CTBS,COX8A,IMPDH1,ACAT1,NDUFS5,PSAP,PLOD3,PGAM1,ESYT2 |
| 7.584e-08 | -16.39 | GO_LIGASE_ACTIVITY | MSigDB lists | GO_LIGASE_ACTIVITY | 386 | 98 | 17377 | 2626 |
MIB2,TRIM41,KARS,PPCS,TRAF7,SUCLG1,MRPL39,UBR2,TRIM11,MCCC1,XIAP,UBE2I,KCMF1,BIRC2,RNF103,FANCL,FARSA,MDM2,IARS,SIAH1,ATG3,UBA5,SUCLG2,TTC3,MARCH2,RNF19A,RNF169,RLIM,PRPF19,ACSL5,LARS,TRIM8,BIRC3,RBX1,HARS,RNF25,TOPORS,KIAA1586,BRCA1,POLG2,TRIM28,TRIM4,RAD18,NSMCE2,RNF38,IARS2,UHRF2,QRSL1,TRIM32,SMURF1,XRCC4,CBX4,GCLM,NADSYN1,TRIP12,SHPRH,ZFP91,BRAP,CBLL1,ZNRF3,UBE4A,WWP2,HERC3,RFWD3,GART,MEX3C,GATC,HUWE1,ZNRF2,PPIL2,LTN1,SLC27A4,UBE3B,UBE3C,RNF135,LRSAM1,UBE2M,RNF5,CARS2,TNFAIP3,AACS,ACSL3,RFFL,UBE4B,SYVN1,TARS,ADSS,EPRS,MTHFD2,TTLL4,QARS,SIAH2,DTX4,PIAS2,RNF14,RNF139,ACSF2,RNF114 |
| 7.627e-08 | -16.39 | GO_RESPIRATORY_CHAIN | MSigDB lists | GO_RESPIRATORY_CHAIN | 77 | 31 | 17377 | 2626 |
NDUFA5,COX15,NDUFV2,NDUFS1,NDUFB6,UQCR10,NDUFA4,COX4I1,CYCS,NDUFA7,NDUFB1,FOXRED1,SDHA,PARK7,NDUFS7,NDUFS4,SDHB,NDUFV1,NDUFA2,NDUFB4,NDUFA11,COX7A2L,COX8A,COX5A,NDUFB9,UQCRH,NDUFS8,CYC1,NDUFS5,NDUFA3,HIGD2A |
| 7.645e-08 | -16.39 | YU_MYC_TARGETS_UP | MSigDB lists | YU_MYC_TARGETS_UP | 38 | 20 | 17377 | 2626 |
PLK1,TXN,ASPM,MKI67,NUP54,RRM1,RACGAP1,FAM136A,ANLN,CCNB1,DTL,CLIC4,PCNA,BIRC5,UCHL5,TFDP1,KPNA2,HMGB2,CCNB2,STRAP |
| 7.651e-08 | -16.39 | GSE3982_EFF_MEMORY_CD4_TCELL_VS_TH2_DN | MSigDB lists | GSE3982_EFF_MEMORY_CD4_TCELL_VS_TH2_DN | 192 | 58 | 17377 | 2626 |
H2AFZ,PPP1R2,GSPT2,TKT,RRM1,LAMTOR3,KIF23,NDUFA4,THRAP3,BLM,NDUFS4,MCTS1,OIP5,FKBP1A,PA2G4,CLIC4,CCNA2,CD3EAP,MCM5,KIF14,BDH1,FUT8,DAPK1,EFCAB11,TIMELESS,RNASEH2A,CYC1,NFU1,MRPL40,MRPL11,LUC7L2,SEH1L,HNRNPM,TACC3,RYBP,PLK1,PPIF,TDP1,TIMM8B,BRD4,LAP3,MRPL12,KIF15,RRM2,USP22,BORA,CLNS1A,PRIM1,SDHB,CDC27,PRDX3,PFDN4,PRPS2,DBI,CAB39,PRMT7,MRPL3,TUBB |
| 7.700e-08 | -16.38 | STAT6 (signal transducer and activator of transcription 6) | protein interactions | 6778 | 69 | 30 | 17029 | 2761 |
TSTA3,POLK,PGGT1B,AACS,SND1,VKORC1,DAZAP2,API5,ZNF407,KDM3A,ETS1,TRIM28,ZNF92,SRXN1,PTPN2,ANKZF1,IRF4,GART,JAK1,STAT6,PPM1G,RAD23B,KIF22,NCOA1,AHCYL1,STAT3,IGBP1,NCOA2,SSSCA1,RLIM |
| 7.808e-08 | -16.37 | PPP1CB (protein phosphatase 1 catalytic subunit beta) | protein interactions | 5500 | 255 | 75 | 17029 | 2761 |
MAX,LUZP1,PPP1R15B,ACTR3,MYH9,SIRT2,CCNB1,SEC16A,SAFB2,PPP1R16B,PAPOLA,HNRNPA2B1,DST,UBXN2A,INTS1,PPP1R12C,TP53BP2,PLCL2,CLTB,RBM12B,CFL1,SHOC2,PPP1R18,TLK1,CUL3,WDR82,CDCA2,BRCA1,ANLN,TRIM28,DHX15,HSPA4,KIF18B,PDRG1,SAFB,UBXN2B,CORO1C,MYO18A,PQBP1,OGT,ACTB,TMEM33,UNK,PPP1R2,PPP1R12A,UBXN1,DHX9,RACGAP1,WDR5,RB1,HDAC7,PPP1R8,CAPZA1,ZNF326,BCL2,MYO5A,SPTAN1,RPAP3,PPP1R9B,WDR1,ILF3,PACS1,PLEC,CAPZA2,LRRC1,MATR3,CCT8,DAPK3,INF2,KIF18A,RBMX,HNRNPH3,PPP1R11,CDK2,CDKN2A |
| 7.838e-08 | -16.36 | GSE3982_MAC_VS_NEUTROPHIL_LPS_STIM_UP | MSigDB lists | GSE3982_MAC_VS_NEUTROPHIL_LPS_STIM_UP | 183 | 56 | 17377 | 2626 |
TCF12,KARS,MCM10,RPLP2,WDYHV1,TIA1,RPL15,CUL1,UBE2Q1,GTF3A,POMP,COPB2,RGS1,BCAT2,MCTS1,COQ4,SUV39H2,GOT2,ZNHIT6,ATIC,PRC1,PIGG,BCAP29,TARDBP,TP53BP2,AHCYL1,MRPL11,ADCY7,NAGPA,PHF10,MIOS,ASPM,TMEM126B,ZMYND11,SEPT8,GALNT7,PCGF1,PRPSAP1,EIF3G,ZFR,CLNS1A,XRCC5,DDX23,NAP1L1,MAGT1,CERS6,DCK,PSMD8,ITGB1,LRPPRC,COX8A,SIL1,CHEK2,SNRPG,MRPL13,FUBP1 |
| 7.838e-08 | -16.36 | GSE28237_FOLLICULAR_VS_LATE_GC_BCELL_DN | MSigDB lists | GSE28237_FOLLICULAR_VS_LATE_GC_BCELL_DN | 183 | 56 | 17377 | 2626 |
WASF2,GOLPH3L,HNRNPUL2,TMEM109,TRAK1,CUL1,SIKE1,GYG1,MAP1LC3B,BECN1,HMG20A,RPL23A,EEF2K,GOLM1,RAP1A,VASP,DPYSL2,LPIN2,SRI,FAM89B,FNIP2,RNF19A,MVP,F2R,SAP30L,KCNAB2,TRIM14,PRIM2,ASPM,NSDHL,RAB7A,TEX10,SMU1,PSMB7,SMC2,SEPT7,RAB1A,KIF18A,GALNT2,PPP2R5A,PDLIM1,DCK,STAT6,SNAP23,CEP55,STX18,CDCA5,NLRC5,MEGF9,CNOT6,SMAD1,RBBP4,CLN3,BRD9,SLC25A39,TMEM131 |
| 7.838e-08 | -16.36 | GSE41867_DAY8_VS_DAY15_LCMV_CLONE13_EFFECTOR_CD8_TCELL_DN | MSigDB lists | GSE41867_DAY8_VS_DAY15_LCMV_CLONE13_EFFECTOR_CD8_TCELL_DN | 183 | 56 | 17377 | 2626 |
NDUFA5,CMAS,SARNP,MRPL9,EIF3D,DCTN2,SIKE1,NIT2,NANS,FKBP2,PSMD9,POLR3K,CD320,MED8,NDUFA2,TIMM23,RPN2,NDUFS8,CENPM,MRPL11,SGCB,SEH1L,RNF5,TIMM50,ACSL5,TDP1,MAPRE2,CDC123,NSDHL,LDHA,WIPF1,CKAP2L,NDUFA7,TOMM40,SHCBP1,MAP2K2,CCDC127,GLOD4,CBX3,STOML2,EIF3K,DAP3,C1orf131,MID1IP1,HSPB11,GOLGA7,QARS,MAP4,WDR7,GPI,BTF3,WDR76,IGBP1,PSMC1,VPS29,FAF1 |
| 7.838e-08 | -16.36 | GSE17974_CTRL_VS_ACT_IL4_AND_ANTI_IL12_48H_CD4_TCELL_DN | MSigDB lists | GSE17974_CTRL_VS_ACT_IL4_AND_ANTI_IL12_48H_CD4_TCELL_DN | 183 | 56 | 17377 | 2626 |
MIF,TMEM106C,TMUB1,CASP6,DHPS,PTTG1,MRPS26,CDCA3,UCK2,NIT2,HAUS4,SLC29A1,TWF2,TMEM165,SLC25A43,RMI1,MRPL19,BCAT2,HNRNPA2B1,LYAR,SNRNP25,GOT2,CENPJ,MCM5,BDH1,PRC1,MEA1,TMEM99,C12orf75,TDP1,NTPCR,PSRC1,TCTEX1D2,CRNKL1,SCFD2,CCDC34,WDHD1,BOLA1,C9orf40,TXNL4A,COMMD4,PRIM1,KIF2A,HSPB11,KEAP1,PSMD8,TFDP1,NRM,DNAJC17,FAM83D,COX5A,ACAT1,RUVBL2,GPI,FAF1,RAD51D |
| 7.840e-08 | -16.36 | GCM_APEX1 | MSigDB lists | GCM_APEX1 | 109 | 39 | 17377 | 2626 |
H2AFZ,DHPS,POLR2K,SUMO2,NACA,DHX9,SNRPD3,PCBP1,ERH,RPL17,DUT,SRSF4,CAPZA1,TRA2B,RPL19,PCBP2,CFL1,HNRNPM,RPL29,HMGN1,RHOA,NASP,POLR2G,CDC123,RPL6,PSMA1,RPS24,SLBP,BCLAF1,FXR1,CBFB,DDX39A,TRIM28,SNRPA,NAP1L1,PSMD8,QARS,YWHAZ,SRSF3 |
| 7.852e-08 | -16.36 | GO_POSITIVE_REGULATION_OF_PROTEOLYSIS | MSigDB lists | GO_POSITIVE_REGULATION_OF_PROTEOLYSIS | 351 | 91 | 17377 | 2626 |
SUMO2,MYH9,CUL1,SIRT2,UBQLN2,CCNB1,APP,ANKIB1,BCAP31,FBXO22,USP5,MDM2,PSMD1,PSMA6,CDKN1B,PDCD2,ANAPC7,RNF19A,F2R,CLN6,SENP1,HTRA2,PLK3,BAK1,PLK1,PSMA8,PSMB7,CUL3,CDC23,RAB1A,PSMB9,CDC16,RPS27A,PSMD8,PSMD3,AXIN1,NSMCE2,SOCS4,OGT,ADAM9,TRIM32,DVL1,CLU,SMURF1,PSMC1,CSNK1D,HDAC2,GORASP1,DNAJB2,DAP,NKD2,CYCS,PAWR,PSMD9,PSEN1,CSNK1A1,RHBDD1,APOPT1,FBXO5,DDRGK1,TFAP4,PSMD2,RB1,PTEN,DAPK1,STAT3,SOCS5,GBA,PSMA1,ANAPC2,CYFIP2,PICALM,PSMB3,FADD,FAS,PSMC4,HSPBP1,PDCD6,KEAP1,GOLGA2,CDC27,PML,MAP3K5,RNF14,UBE2C,ESPL1,RNF139,CDKN2A,IFI16,ANAPC4,RNF114 |
| 7.913e-08 | -16.35 | GRAHAM_CML_DIVIDING_VS_NORMAL_QUIESCENT_UP | MSigDB lists | GRAHAM_CML_DIVIDING_VS_NORMAL_QUIESCENT_UP | 174 | 54 | 17377 | 2626 |
MCM10,MRPS15,CENPF,TPX2,RRM1,RACGAP1,KIF2C,CCNB1,NCAPG,STMN1,FANCI,LMNA,SPAG5,SAC3D1,FBXO5,OIP5,SNRNP25,SUB1,CCNA2,MCM5,DUT,PRC1,RNASEH2A,CENPM,MINPP1,LRRC59,NUP85,GINS1,PPIF,TK1,RFC3,ASPM,RAD51AP1,PBK,CPOX,KIF15,RRM2,NUSAP1,CDC6,AURKB,BRCA1,SMC2,MCM2,KIF11,SYNCRIP,KIF18B,PDLIM1,BIRC5,CEP55,H2AFX,KPNA2,CCNB2,UBE2C,ESPL1 |
| 7.913e-08 | -16.35 | GSE24671_BAKIMULC_VS_SENDAI_VIRUS_INFECTED_MOUSE_SPLENOCYTES_DN | MSigDB lists | GSE24671_BAKIMULC_VS_SENDAI_VIRUS_INFECTED_MOUSE_SPLENOCYTES_DN | 174 | 54 | 17377 | 2626 |
ZNF207,CCNC,MUT,SCOC,UGP2,THOC1,PLAGL2,ARFIP2,SIKE1,GLRX3,PITHD1,BZW2,SNUPN,DNAJC8,VMP1,MTMR4,RAB35,TRMU,TTC9C,NSFL1C,NOC2L,PIGG,YBX1,TTC4,C8orf59,CPSF4,PDIA6,SENP1,POC5,MRPL32,TRIM14,TMX1,NUDC,RBM15B,CSTF1,ACSL5,NOL12,TXNL1,GUK1,RNASEH2C,SIGMAR1,BTAF1,BMS1,OGFR,MAP2K2,EIF3G,MAT2A,DSN1,RBL1,QARS,NFIL3,C4orf46,TAF12,ANAPC4 |
| 8.055e-08 | -16.33 | transcription-coupled nucleotide-excision repair | biological process | GO:0006283 | 73 | 30 | 17256 | 2622 |
COPS8,USP7,ERCC1,HMGN1,RFC3,POLR2I,POLR2G,POLR2L,RBX1,POLK,POLR2K,XAB2,PPIE,POLR2D,RFC2,POLR2A,RPA1,RPA2,PCNA,POLR2J,RPS27A,XPA,COPS7B,TCEA1,AQR,ZNF830,COPS6,GTF2H2,DDB1,PRPF19 |
| 8.153e-08 | -16.32 | SUPT5H (SPT5 homolog, DSIF elongation factor subunit) | protein interactions | 6829 | 155 | 52 | 17029 | 2761 |
FGFR1OP,C9orf78,ZNF496,MCM10,POC1A,CSNK2A1,NENF,BLM,ATP6V1B2,CDC73,PNO1,LMNA,PAPOLA,CSDE1,SUB1,GART,SMC3,PIN1,SEC24C,SSBP3,MSH2,CTR9,RPRD1B,MSH6,EEF1D,CARM1,POLR2I,DCAF6,POLR2G,POLR2L,MIOS,HNRNPF,POLR2D,CUL3,WIPF1,RTF1,RANGAP1,NFATC2,BRCA1,POLR2A,XRCC5,IWS1,PAF1,PCM1,POLR2J,VPS26B,NSMF,H2AFX,TAF6,PPP2R2D,TERF1,IFI16 |
| 8.290e-08 | -16.31 | macroautophagy | biological process | GO:0016236 | 160 | 51 | 17256 | 2622 |
CHMP2A,PRKAB1,TOMM20,DYNLL1,PRKAA1,RAB23,CSNK2A1,ATG2B,MAP1LC3B,BECN1,PSEN1,STAM,VPS25,ATG4A,UBXN2A,VMP1,RAB35,ATG3,EI24,NSFL1C,ATG13,PACS2,ULK3,ATG9A,RB1CC1,RAB7A,GBA,WDR81,VDAC1,TOMM40,CHMP2B,RAB1A,PLEKHF2,MFN2,MTMR3,HGS,CHMP4A,PLAA,RPS27A,UBXN2B,TOMM6,SNAP29,VIPAS39,CHMP4B,VPS4A,WIPI2,CLN3,SMURF1,WDR45B,SNX14,SNAPIN |
| 8.291e-08 | -16.31 | endoplasmic reticulum subcompartment | cellular component | GO:0098827 | 1049 | 217 | 18223 | 2701 |
TMED7,PIGM,TMEM203,COPA,PIGQ,TMEM109,MOGS,AGPAT1,TAP1,CDIPT,FKBP2,IKBIP,SEC16A,BECN1,RNF103,SSR1,DST,NUP210,CDC42,THADA,RAB35,CYB5RL,SRI,ZFYVE27,CISD2,MARCH2,RNF26,TECR,SPTSSA,LRRC59,PGAP2,DPM1,ATG9A,APH1A,ESYT1,PITPNB,ICMT,MCFD2,KRTCAP2,RAB2B,RHEB,ALG3,AGPAT2,STT3A,TMED10,RPS27A,MIA2,SARAF,PIEZO1,CLN3,RPS26,RTN3,STARD3NL,SVIP,PIGN,AGTRAP,SEC61G,DNAJB2,HLA-E,UBXN1,SLC35B1,RAB6A,TMED3,NOTCH2,PSEN1,COPG2,RHBDD1,NPLOC4,COPB2,DDRGK1,CD59,FKBP1A,RPN1,RNF121,NUS1,PYURF,LRRC8D,RNFT1,DAD1,EI24,ARL6IP1,PIGG,RTCB,SLC27A4,BCL2,PCYT2,LPCAT1,TMED2,PREB,FDFT1,KDELR1,EIF5A,PIGT,SIGMAR1,RB1CC1,ERLIN1,NSDHL,ACSL3,ERO1A,RDH10,MAN1B1,SSR2,SYVN1,VKORC1,CYB5A,RDH11,DERL1,SEC31A,MOSPD3,SCARB2,GALNT2,ORMDL2,ERGIC3,LPCAT4,SAMD8,SMPD4,MAP3K5,TMEM14A,PTDSS1,APOL2,RNF139,TMEM106C,RHOG,ATXN3,CHERP,COPE,RAC1,VTI1A,TMEM97,ADPGK,SLC35B2,LCLAT1,KTN1,EXT2,BCAP31,SEC11A,RAB21,ATP2A2,LPIN2,TAP2,ANKRD13C,BCAP29,RPN2,CYB5R1,LMAN1,AHCYL1,PDIA6,CLN6,HTRA2,MOSPD1,ANKLE2,ACSL5,UBQLN4,SEC61B,ATP13A1,ERMP1,TOR1AIP2,TMEM147,DNAJA1,PKMYT1,RAB1A,SERP1,RHBDF2,SURF4,DDOST,SEC61A1,CERS6,SCAP,SEL1L,CANT1,NCLN,MBOAT1,ATF6,REEP4,ABCA1,TMEM33,CDS2,TMX3,AGPAT3,SDF2L1,REEP5,WRB,DNAJB9,HLA-A,SPPL2A,EBP,SEC24C,RRBP1,SLC35B4,ATG13,YIF1B,OSTC,CAMK2G,TMX1,RNF5,ELOVL5,MLEC,RHOA,PNPLA8,WDR81,SPPL2B,YIF1A,HLA-B,PLD3,RAB18,PDCD6,MAGT1,OSBPL8,STX18,PML,PGRMC1,ASNA1,PKD2,SPCS3,PLOD3,FAF1,ESYT2 |
| 8.309e-08 | -16.30 | SPRTN (SprT-like N-terminal domain) | protein interactions | 83932 | 95 | 37 | 17029 | 2761 |
ATXN3,UBXN1,PMS2,BRAP,ATP5F1B,NPLOC4,GTF2F1,NAPG,PCNA,CLIC4,ATP2A2,HUWE1,NSFL1C,YBX1,STRAP,STAU1,TUFM,LACTB,SRSF5,VDAC1,TRIM28,SRSF1,DDX17,CAND1,RPA1,MAGED2,ATP1A1,RAD18,SYNCRIP,PSMD3,BCL7C,LRPPRC,VCPIP1,DDX5,ATP5F1A,HNRNPDL,ZC3HAV1 |
| 8.469e-08 | -16.28 | regulation of protein ubiquitination | biological process | GO:0031396 | 187 | 57 | 17256 | 2622 |
RPS2,TRIP12,PHF23,GORASP1,DNAJB2,UBXN1,XIAP,DCUN1D4,PSEN1,BIRC2,PARK7,MAD2L2,FANCI,WDR48,ZER1,RPL11,FBXO5,CDK5,FKBP1A,UBXN2A,PTEN,MTA1,PIN1,FEM1B,CTR9,CHP1,PLK1,BIRC3,TNFAIP3,GTPBP4,CUL3,TOPORS,DNAJA1,BRCA1,ADRB2,DCUN1D5,RAB1A,SOX4,PTTG1IP,PEF1,ISG15,HSPA1B,DERL1,PDCD6,HSPBP1,PLAA,GOLGA2,GPS2,AXIN1,LIMK1,SIAH2,OGT,TICAM1,PARP10,ARRB2,UBE2C,RNF139 |
| 8.480e-08 | -16.28 | RPL19 (ribosomal protein L19) | protein interactions | 6143 | 151 | 51 | 17029 | 2761 |
KARS,RPS15,NIFK,RPS2,CYLD,NOP2,RPLP2,RPL15,CUL1,SND1,RPL11,RPL23A,RPA2,EIF4A3,RPL17,TARDBP,PTGES3,FBL,LUC7L2,HNRNPM,STAU1,RPL35,MRPL12,RPS10,RPL6,CUL3,ILF3,RPL8,RPL38,TUFM,RPS24,RPL27A,SLC25A5,RPS9,RPSA,RPA1,CAND1,RPL36,SEC61A1,RPL32,RPS27A,QARS,RPS14,RPLP1,H2AFX,DDX5,RRS1,CDK2,ARRB2,RPS26,TERF1 |
| 8.492e-08 | -16.28 | GCM_CSNK2B | MSigDB lists | GCM_CSNK2B | 93 | 35 | 17377 | 2626 |
H2AFZ,DHPS,POLR2K,RAF1,SUMO2,NACA,SNRPD3,PCBP1,RPL11,SF3B2,RPL17,SRSF4,BUD31,YBX1,RPL19,TCEA1,PCBP2,CFL1,HNRNPM,RPL29,RHOA,NASP,POLR2G,RPL6,PSMA1,EIF4H,DDX39A,TRIM28,SNRPA,RPSA,RPL32,GPS2,QARS,PSMD8,YWHAZ |
| 8.547e-08 | -16.28 | RPS3 (ribosomal protein S3) | protein interactions | 6188 | 251 | 74 | 17029 | 2761 |
CYLD,RPLP2,DYNLL1,CUL1,CSNK2A1,SND1,CCNB1,RPL11,RPL23A,KRR1,MDM2,CRY2,TARDBP,CDC5L,CCT2,RPL29,RPL35,VHL,WBP2,RPL38,CUL3,BRCA1,MCM2,SLC25A5,POLG2,RPS9,RPSA,MAT2A,EIF3A,CHAF1A,RPL37,HSPA4,RPS27A,RPS14,RPLP1,H2AFX,RRS1,FAU,ARRB2,SMURF1,RPS26,PARD3,NIFK,RPS15,UNK,RPS2,RPL15,CDC73,TUBGCP2,PNO1,PTEN,HUWE1,RPL17,AHSA1,RPL19,FBL,STAU1,RPL8,ILF3,TUFM,RPL6,RPS10,RPS24,RPL27A,CAND1,RPL36,NAP1L1,UPF1,RPL32,ATP5F1A,CDK2,CD81,MRPL3,BYSL |
| 8.589e-08 | -16.27 | GSE24026_PD1_LIGATION_VS_CTRL_IN_ACT_TCELL_LINE_DN | MSigDB lists | GSE24026_PD1_LIGATION_VS_CTRL_IN_ACT_TCELL_LINE_DN | 188 | 57 | 17377 | 2626 |
ZNF207,PKP4,C1orf112,TCF3,YTHDC2,RBM8A,MON1B,STARD7,UBE2Z,SMC6,CTCF,KIF2C,TWF2,PMVK,PABPC4,NRF1,NFATC3,IARS,SAR1A,UTP18,NUP107,PRC1,AHCY,GEMIN4,LRRC59,STRAP,PPP6R1,FTSJ3,CARS2,AMPD2,TDP1,CCT2,ASPM,MFNG,CUL3,SLBP,DCTD,RANGAP1,SMC2,MCM2,KIF11,PDE3B,KDM3A,TRIM28,DHX15,RPA1,CAND1,MAP3K4,SEC61A1,KIF18B,BIRC5,TATDN2,E2F1,KPNA2,PDSS2,MRPL3,C7orf26 |
| 8.589e-08 | -16.27 | GSE15930_STIM_VS_STIM_AND_IFNAB_72H_CD8_T_CELL_DN | MSigDB lists | GSE15930_STIM_VS_STIM_AND_IFNAB_72H_CD8_T_CELL_DN | 188 | 57 | 17377 | 2626 |
SEPHS2,KIF3B,SMAP1,MIF4GD,MRPL9,GNPNAT1,DNAJB2,COPE,ASAH1,ARF1,LACTB2,DNAJB1,PRPF39,ATP6V1B2,POLR3K,KTN1,PIP4K2A,SPAG5,MBD4,RAD23A,WWP2,PTPN2,VMP1,MCM5,TANK,AKAP8,PDCD2,TAGLN2,TCEA1,TALDO1,DVL2,CSRP1,LRBA,TBRG4,WDHD1,UTP3,NUTF2,CAPZA2,SEPT7,MRPS14,MATR3,ISG15,ALG3,SMAD2,POLR2J,TULP3,CDCA5,MRPL27,OGT,LRPPRC,TBPL1,NUP62,FKBP5,ROCK1,NCOA1,RBBP4,PGAM1 |
| 8.589e-08 | -16.27 | GSE9509_LPS_VS_LPS_AND_IL10_STIM_IL10_KO_MACROPHAGE_10MIN_DN | MSigDB lists | GSE9509_LPS_VS_LPS_AND_IL10_STIM_IL10_KO_MACROPHAGE_10MIN_DN | 188 | 57 | 17377 | 2626 |
PPCS,LZTR1,MRPL42,AGRN,GNPDA1,MUM1,HNRNPUL2,PCSK7,KLC1,ZFYVE21,SIKE1,SLC4A2,CSNK1A1,GFM2,SEC11A,GOLM1,MLX,MED8,MTMR4,PPIL2,SLC35B4,MSH2,BRD7,ATP6V0A2,MAVS,CYB5R1,OSTC,CAMK2G,FDFT1,POLR2G,TYW1,RNF25,NARF,DNAJC9,UBE4B,CDC23,ICAM2,PRMT2,FOXRED1,TAZ,DAP3,TBC1D17,TTC13,DHX16,CHCHD1,QARS,CEBPG,MRFAP1L1,TAF12,YY1,NDE1,LTA4H,YWHAH,TSTD2,RTN3,CHID1,VPS29 |
| 8.589e-08 | -16.27 | GSE45365_NK_CELL_VS_CD8_TCELL_MCMV_INFECTION_UP | MSigDB lists | GSE45365_NK_CELL_VS_CD8_TCELL_MCMV_INFECTION_UP | 188 | 57 | 17377 | 2626 |
SLC12A7,CHMP2A,GMFG,KIAA0100,NIPA2,GMCL1,GYG1,CDIPT,OAT,SPR,IFT27,REEP5,WRB,CPNE3,SSR1,PCYOX1L,PRNP,SLC25A36,ARPC5,ATIC,GEMIN6,TTC3,CORO1A,GPD1L,DNMT1,ARL5A,PDLIM2,SOCS5,ADCY7,MLEC,SEPT9,PPT1,RAB7A,DENND4C,RCOR1,FRAT2,RAB1A,NDRG3,GAR1,PICALM,RHEB,PRIM1,SDHB,OSBPL11,CCDC86,TMED10,TULP3,PRPS2,PGRMC1,CCDC69,ACAT1,FN3KRP,ACADM,MAP3K5,CHPT1,COIL,IFI16 |
| 8.589e-08 | -16.27 | GO_POSITIVE_REGULATION_OF_PROTEIN_MODIFICATION_BY_SMALL_PROTEIN_CONJUGATION_OR_REMOVAL | MSigDB lists | GO_POSITIVE_REGULATION_OF_PROTEIN_MODIFICATION_BY_SMALL_PROTEIN_CONJUGATION_OR_REMOVAL | 188 | 57 | 17377 | 2626 |
GORASP1,PHF23,DNAJB2,XIAP,CUL1,CCNB1,DCUN1D4,PSMD9,BIRC2,FANCI,FBXO22,FBXO5,FKBP1A,PSMD2,PSMD1,PSMA6,PTEN,PIN1,MTA1,CTR9,ANAPC7,PLK1,BIRC3,PSMA8,PSMB7,PSMA1,ANAPC2,TOPORS,BRCA1,ADRB2,DCUN1D5,CDC23,PTTG1IP,RAB1A,TOLLIP,PSMB9,PSMB3,PSMC4,MASTL,DERL1,HSPBP1,CDC16,GOLGA2,CDC27,RPS27A,PSMD8,AXIN1,PSMD3,TICAM1,CLU,ARRB2,UBE2C,SMURF1,PSMC1,RNF139,ANAPC4,CDKN2A |
| 8.589e-08 | -16.27 | GSE10239_MEMORY_VS_KLRG1INT_EFF_CD8_TCELL_DN | MSigDB lists | GSE10239_MEMORY_VS_KLRG1INT_EFF_CD8_TCELL_DN | 188 | 57 | 17377 | 2626 |
SKA3,LYRM4,DHPS,TMEM41B,ACTR3,TRMT6,CENPF,DBF4,LAMTOR3,NIPA2,KIF2C,AP3S1,DUSP22,KCMF1,LIN9,RFWD3,C1GALT1,LPIN2,TRA2B,ANP32A,KIF22,CLDND1,CARM1,CPNE1,TTPAL,GABPA,NUDT4,IDH3A,SNRPB,TEX10,CYP20A1,FBXO9,MTMR6,SLBP,CDCA2,AURKB,DCUN1D5,ANLN,KDM1B,CCNF,C9orf40,SERP1,AKAP1,CAT,PON2,RAD51C,CDC16,SEC23IP,DGCR8,HMGB2,CHMP4B,CHEK2,CDK2,NGLY1,RTN3,ESPL1,RHEBL1 |
| 8.589e-08 | -16.27 | GSE1460_DP_THYMOCYTE_VS_NAIVE_CD4_TCELL_ADULT_BLOOD_UP | MSigDB lists | GSE1460_DP_THYMOCYTE_VS_NAIVE_CD4_TCELL_ADULT_BLOOD_UP | 188 | 57 | 17377 | 2626 |
POLA2,ZNF207,HSPH1,FEZ2,HNRNPAB,FOXM1,GORASP1,C1orf112,MAGED1,CDK2AP2,C5orf30,CSNK2A1,SND1,PSMD9,RMI1,MYL6B,FANCI,COPB2,SPAG5,MCTS1,PSMA6,EIF4A3,AP3S2,SIVA1,UBA5,GMEB1,EFCAB11,STRAP,SLC25A1,SAP30,PTPRK,TIMP2,MKLN1,IDH3A,KIF15,EZR,SREK1,NUP155,BRCA1,SMC2,LRRC1,ICMT,SHCBP1,PEF1,FADD,XRCC5,CHCHD3,PPP2CA,PEX5,KIF18B,PDLIM1,DBI,TFDP1,SRSF3,USP11,UBE2C,HDAC2 |
| 8.589e-08 | -16.27 | GSE37301_LYMPHOID_PRIMED_MPP_VS_RAG2_KO_NK_CELL_UP | MSigDB lists | GSE37301_LYMPHOID_PRIMED_MPP_VS_RAG2_KO_NK_CELL_UP | 188 | 57 | 17377 | 2626 |
KIF3B,FAM208B,TOMM20,MRPS2,SRSF6,EIF3D,MON1B,NUP54,PLAGL2,THRAP3,PRPF39,RGS2,PNO1,IRF4,DDX56,TNS3,CLIC4,AHCTF1,MEX3C,UTP18,GRSF1,AKAP8,JOSD1,TTC4,POLR1B,AHCYL1,CDK12,LDHB,RPP25,PPIF,MAPRE2,DDX24,TMEM39A,IDH3A,LDHA,EZR,SLC25A22,TMEM147,GAR1,EIF3G,ZFR,AKAP1,ADSS,PPP2CA,HGS,ATP1A1,UAP1,ETS2,SEL1L,ADAM9,ATP6V0C,RBPJ,RRS1,EHD4,NUDT11,PGAM1,IPO4 |
| 8.659e-08 | -16.26 | signal transduction involved in cell cycle checkpoint | biological process | GO:0072395 | 77 | 31 | 17256 | 2622 |
PLK3,PLK1,PRKDC,BTG2,BABAM1,BRCA1,CCNB1,SOX4,CNOT11,CNOT3,CNOT9,DTL,BABAM2,PCNA,MDM2,RPS27A,CENPJ,E2F4,TFDP1,E2F1,PML,CDKN1B,GTSE1,CNOT6,CHEK2,TFDP2,CNOT6L,CDK2,CARM1,CDC5L,PRPF19 |
| 8.689e-08 | -16.26 | PENG_GLUCOSE_DEPRIVATION_DN | MSigDB lists | PENG_GLUCOSE_DEPRIVATION_DN | 161 | 51 | 17377 | 2626 |
EIF1B,MYEF2,FANCI,CREM,DST,OIP5,RB1,ATP6V0B,RAP1A,ATP2A2,ARPC5,DPYSL2,SEC24C,RRBP1,CAPZA1,MSH2,FAM89B,BCL2,CHTOP,ZC3H3,SMC4,TERF2,MKI67,KRAS,GORASP2,DNAJA1,RAB1A,SLC25A5,KIF11,EIF4H,H2AFV,PICALM,EIF3H,ARF4,ZFR,SRSF1,XRCC5,NAP1L1,PPP2R5A,HNRNPR,ELMO1,TIMM17A,E2F4,MAP4,E2F1,ANP32E,RBBP4,TRAF5,ESPL1,IFI16,FUBP1 |
| 8.763e-08 | -16.25 | GSE7218_IGM_VS_IGG_SIGNAL_THGOUGH_ANTIGEN_BCELL_UP | MSigDB lists | GSE7218_IGM_VS_IGG_SIGNAL_THGOUGH_ANTIGEN_BCELL_UP | 179 | 55 | 17377 | 2626 |
SLC30A9,NADSYN1,CMAS,IMMT,NOP2,IVNS1ABP,MDH2,RAF1,GNE,CENPF,RACGAP1,NUF2,KIF2C,SND1,BLM,ITGB5,NRF1,FBXL6,INTS7,RALB,PIK3R2,FEM1B,ZBTB22,POLR1B,RNF26,DNMT1,MGAT5,PLK1,TACC1,SIGMAR1,PBK,VDAC2,MKI67,ATP6V0A1,ADSL,DDX20,BICD2,CCNF,SHCBP1,KIF11,H2AFV,TRIM28,TAF2,RAB18,FNTA,KIF18B,DGCR8,ACAT1,BEND6,REEP4,BRWD3,LTA4H,CCNB2,ZMAT3,DDB1 |
| 8.763e-08 | -16.25 | GSE17721_CTRL_VS_POLYIC_6H_BMDC_UP | MSigDB lists | GSE17721_CTRL_VS_POLYIC_6H_BMDC_UP | 179 | 55 | 17377 | 2626 |
WASF2,IER2,GCLM,NAT9,LZTR1,TMEM203,CASP6,IVNS1ABP,DNAJB2,UBXN1,CUTA,LAMTOR3,HCFC1R1,UBE2I,SEC16A,BCAP31,EBP,TMEM179B,RPA2,RAP1A,CCNA2,NDUFA2,IL6ST,CAPZA1,BCAP29,TALDO1,NUP85,PDLIM2,VOPP1,AGGF1,GALC,NUDT4,SLC26A6,FRAT2,RABIF,ARHGDIB,ADRB2,NDUFA7,ARPC1A,ECH1,NEU1,EIF3H,ASF1B,ORMDL2,OAZ2,RPLP1,MPV17,FTSJ1,QRSL1,PDXK,ATP6V1C1,USP11,CDK2,USF2,HIGD2A |
| 8.784e-08 | -16.25 | PDCD6 (programmed cell death 6) | protein interactions | 10016 | 99 | 38 | 17029 | 2761 |
MIF,PDCD6IP,TXN,HNRNPUL2,TKT,CUL1,IKBIP,CCNB1,PCBP1,HAUS2,PABPC4,FERMT3,CRKL,CLIC4,CCNA2,DAPK1,ANXA5,TARDBP,LMAN1,PABPC1,IMPA2,CPNE1,TSTA3,HEBP2,MCM2,PEF1,FAS,CAND1,PDCD6,CSK,HNRNPH3,MAP4,H2AFX,MAP3K5,IGBP1,CDKN2A,ANXA11,FUBP1 |
| 8.847e-08 | -16.24 | GO_COVALENT_CHROMATIN_MODIFICATION | MSigDB lists | GO_COVALENT_CHROMATIN_MODIFICATION | 317 | 84 | 17377 | 2626 |
MBD1,ASH1L,DNMT3A,ATXN3,KDM4A,UBR2,CXXC1,SUZ12,SIRT2,TAF6L,CCNB1,MEAF6,SAP130,TET3,KDM2A,BRPF3,MTA1,TAF5L,ATF2,SAP30L,ARID4A,CARM1,SAP30,RYBP,USP34,KDM3B,BAZ2A,KAT7,EHMT1,ELP4,WDR82,AURKB,USP22,KDM1B,MBD3,USP21,DOT1L,PAF1,BRMS1,CHD3,OGT,BAZ1B,BEND3,NCOA1,PPP5C,NAA60,EYA2,HDAC2,MECP2,EYA1,PRKAA1,JMJD6,EZH1,SUPT7L,WDR5,CDC73,IRF4,SUV39H2,HUWE1,HDAC7,MBD2,PRDM4,ZNF335,NAA50,CTR9,FBL,NCOA2,KAT2A,MTA2,LDB1,RCOR1,RTF1,PRMT2,PCGF1,MEN1,KDM3A,MBIP,SETD3,PRMT7,RUVBL2,TAF12,RBBP4,CDK2,DDB1 |
| 8.892e-08 | -16.24 | GNF2_SMC2L1 | MSigDB lists | GNF2_SMC2L1 | 32 | 18 | 17377 | 2626 |
RFC3,FOXM1,ASPM,CENPF,MYBL2,RRM1,CDCA8,NUSAP1,SMC2,KIF11,PRIM1,CCNA2,PCNA,KIF18B,BIRC5,CCNB2,ESPL1,SMC4 |
| 9.081e-08 | -16.21 | GO_ORGANELLE_ASSEMBLY | MSigDB lists | GO_ORGANELLE_ASSEMBLY | 454 | 111 | 17377 | 2626 |
ZNF207,RAB14,CHMP2A,PDCD6IP,XIAP,TPX2,AGFG1,CNTROB,BRIX1,BECN1,MAP1LC3B,BIRC2,STAM,MIS12,EDC3,RPL11,RPL23A,KIFC1,CLUAP1,RAB8A,NEK6,ATG3,DNAAF2,RPF2,CORO1A,CEP63,BIRC3,ATG9A,FOPNL,RAB7A,TUBGCP5,TMEM216,CIRBP,RPL38,EZR,AURKB,ANLN,RAB1A,CHMP2B,RPSA,KIF2A,HSPB11,CHMP4A,NIP7,RPS14,E2F4,ATXN2L,ITGB1,CHMP4B,CHEK2,VPS4A,SASS6,CSNK1D,TUBB,KIF3B,RPS15,CENPF,RAB23,KIF23,MEF2A,RACGAP1,HAUS4,ATG2B,PSEN1,RAB11A,HAUS2,TUBGCP2,VPS25,FBXO5,CFLAR,ATG4A,STARD9,CCP110,PTEN,CENPJ,ATG13,MRPL11,IFT46,NSUN4,ATP6V0D1,PACS2,PPAN,DDX28,RHOA,RB1CC1,ASPM,NEK7,WDR1,RPL6,MYBL2,RPS10,BMS1,RAB3IP,EIF2A,KIF11,PATL1,MFN2,HAUS8,HGS,NEK1,ATP6V1D,PCM1,GOLGA2,BIRC5,SNAP29,TBPL1,WIPI2,CENPT,WDR62,CDK2,CHMP7 |
| 9.128e-08 | -16.21 | retrograde vesicle-mediated transport, Golgi to ER | biological process | GO:0006890 | 81 | 32 | 17256 | 2622 |
TMED7,KIF3B,GOLPH3L,COPA,SCYL1,COPE,KIF23,KLC1,RACGAP1,KIF2C,RAB6A,TMED3,COPG2,COPB2,ARF5,KIFAP3,KIF22,TMED2,KDELR1,TMEM115,KIF15,PITPNB,BICD2,RAB1A,KIF11,ARF4,KIF2A,KIF18A,SURF4,TMED10,NSF,STX18 |
| 9.143e-08 | -16.21 | ZRANB2 (zinc finger RANBP2-type containing 2) | protein interactions | 9406 | 84 | 34 | 17029 | 2761 |
UNK,EWSR1,USP39,CSNK2A1,UBQLN2,STAM,PIP4K2A,SRXN1,TTC9C,TRA2B,FBXL7,AHCYL1,TTLL12,LUC7L2,SRPK2,USP34,SRSF11,PIP4K2C,CUL3,PSMA1,SREK1,UBE4B,LUC7L,TBC1D17,SYNCRIP,LUC7L3,ZRANB2,SNRNP70,YY1,SMURF1,UBE2C,ARRB2,SSSCA1,PRPF4B |
| 9.175e-08 | -16.20 | CEP19 (centrosomal protein 19) | protein interactions | 84984 | 103 | 39 | 17029 | 2761 |
WASF2,FGFR1OP,MAPRE1,TRIP12,R3HCC1L,STRN4,YTHDF3,RCOR3,METTL3,COPB2,EDC3,USP5,ANKRD28,NUDT19,NVL,PIN1,PPP6C,MSH2,GPATCH1,KIFAP3,ECD,ILKAP,SCYL3,DVL2,MSH6,SRP72,CDC123,MTMR6,MTR,FKBP3,SLTM,UPF1,SEC23IP,HMGB2,DVL1,PPP6R3,PDLIM5,PARD3,PDCD4 |
| 9.204e-08 | -16.20 | GCM_UBE2N | MSigDB lists | GCM_UBE2N | 148 | 48 | 17377 | 2626 |
WSB2,MECP2,RBM8A,TIA1,CDIPT,FOXO3,REPS1,ABHD16A,MOAP1,FBXO3,SAP130,SMC3,BRPF3,PPIG,CS,ARL6IP1,SS18L1,AHDC1,TARDBP,CHTOP,CREB1,YTHDC1,PHF10,EXOSC6,ZNF84,TSPYL4,BAZ2A,KAT7,NUDT4,CRNKL1,WBP2,ARID1A,PRKRA,ZFAND5,BSDC1,CAND1,MTMR3,VEZF1,EIF4ENIF1,SMAD2,VPS26B,HNRNPR,HNRNPH3,LUC7L3,FN3KRP,CNOT6,ZMIZ1,AAAS |
| 9.349e-08 | -16.19 | GSE32986_UNSTIM_VS_CURDLAN_LOWDOSE_STIM_DC_DN | MSigDB lists | GSE32986_UNSTIM_VS_CURDLAN_LOWDOSE_STIM_DC_DN | 193 | 58 | 17377 | 2626 |
WSB2,TXN,NQO1,TRIP10,DCTN2,HEXB,SIRT2,POMP,SLC35B1,SLC35B2,NCKAP1,BLM,PPP1R16B,PDXDC1,TFRC,SPPL2A,CHKA,FUT8,RAD23B,ARL6IP1,CLDND1,RNF135,SLC12A2,F2R,ATP6V0D1,SLC25A1,PPIF,ORAI2,ELL2,NSDHL,CPOX,RDH10,GBA,E2F3,EZR,NUSAP1,ARHGEF12,VDAC1,PCGF1,MYO1F,MTHFD2,IDE,SURF4,ELMO1,TFE3,CORO1C,PSMD3,DBI,TFDP1,AP1S1,ADAM9,KPNA2,CTSA,GPI,NRBP1,TSPAN5,PFKP,CAPN1 |
| 9.372e-08 | -16.18 | MTCH1 (mitochondrial carrier 1) | protein interactions | 23787 | 59 | 27 | 17029 | 2761 |
USP7,NDUFS1,EWSR1,TIMMDC1,VDAC2,LAMTOR3,TOR1AIP2,TOMM40,VDAC1,DUSP22,PSEN1,SDHA,SPPL2B,PSMC4,PSMD2,RPN1,NDUFV1,TRIM26,ATP1A1,PSMD3,NABP2,IMPDH1,ATP5F1A,PSMC1,ATP6V0D1,FGFR1OP2,PRPF19 |
| 9.388e-08 | -16.18 | Regulation of TP53 Activity | REACTOME pathways | R-HSA-5633007 | 162 | 54 | 10287 | 1696 |
USP7,PRKAB1,TP53RK,PRKAA1,TPX2,RMI2,CSNK2A1,BLM,MAPK14,RMI1,PIP4K2A,MEAF6,JMY,CDK5,RPA2,MDM2,CCNA2,BRPF3,KMT5A,PIN1,NOC2L,BRD7,TP53BP2,MLST8,PDPK1,PLK3,RFC3,AKT2,MTA2,EHMT1,TOP3A,PIP4K2C,RFFL,AURKB,BRCA1,RFC2,MBD3,RPA1,SUPT16H,TAF2,PPP2CA,CHD3,RPS27A,HIPK2,PML,STK11,CHEK2,TAF12,RBBP4,CDK2,TAF6,CDKN2A,HDAC2,SSRP1 |
| 9.418e-08 | -16.18 | REACTOME_HOST_INTERACTIONS_OF_HIV_FACTORS | MSigDB lists | REACTOME_HOST_INTERACTIONS_OF_HIV_FACTORS | 118 | 41 | 17377 | 2626 |
NUP188,RAE1,RAC1,NUP54,ARF1,AP1B1,PSMD9,NUP205,HLA-A,PSMD2,PSMD1,NUP210,PSMA6,BANF1,NUP107,AP1M1,AP2B1,NUP153,NUP85,SEH1L,RBX1,PSMA8,PSMB7,PSMA1,PACS1,NUP155,RANGAP1,SLC25A5,PSMB9,PSMB3,PSMC4,KPNA1,ELMO1,RPS27A,PSMD8,PSMD3,AP1S1,NUP62,PSMC1,AP2S1,AAAS |
| 9.435e-08 | -16.18 | CUL4A (cullin 4A) | protein interactions | 8451 | 288 | 82 | 17029 | 2761 |
USP7,HNRNPAB,RPLP2,DCAF15,CAST,WDTC1,CUL1,SNRPD3,SDHA,GNB2,PABPC4,RPL11,RPL23A,HNRNPA2B1,SAP130,MDM2,PCNA,SYNM,IARS,DDA1,CDKN1B,TFG,COPS8,RBX1,SNRPB,RPL38,HNRNPF,CUL3,SLBP,TOR1AIP2,WDR82,SLC25A22,DCUN1D5,MCM2,SLC25A5,H2AFV,DHX15,DNAJC10,BRWD1,RPS14,MAP4,RPLP1,FUS,CHEK2,COPS6,DCAF5,TUBB,WSB2,UNK,MCM10,EWSR1,RPS2,CDT1,DHX9,TIA1,RPL15,DCUN1D4,WDR5,DTL,BANF1,COPS7B,RPL19,PABPC1,ATP6V0D1,DCAF6,KAT2A,DCAF8,ZNF407,SNRPA,PRDX1,HSPA1B,CAND1,HNRNPH3,DCAF11,DDX5,WDR76,SRSF3,RBBP4,SNRNP70,HNRNPDL,IFI16,DDB1 |
| 9.490e-08 | -16.17 | endoplasmic reticulum membrane | cellular component | GO:0005789 | 1045 | 216 | 18223 | 2701 |
TMED7,PIGM,COPA,TMEM203,PIGQ,MOGS,TMEM109,TAP1,AGPAT1,FKBP2,IKBIP,CDIPT,BECN1,SEC16A,RNF103,SSR1,DST,NUP210,CDC42,THADA,CYB5RL,RAB35,SRI,ZFYVE27,CISD2,MARCH2,TECR,SPTSSA,RNF26,LRRC59,PGAP2,DPM1,ATG9A,APH1A,ESYT1,PITPNB,MCFD2,ICMT,KRTCAP2,RHEB,RAB2B,ALG3,AGPAT2,STT3A,TMED10,RPS27A,MIA2,SARAF,PIEZO1,CLN3,RPS26,RTN3,STARD3NL,SVIP,PIGN,AGTRAP,SEC61G,HLA-E,DNAJB2,UBXN1,NOTCH2,SLC35B1,TMED3,RAB6A,PSEN1,COPG2,RHBDD1,COPB2,NPLOC4,DDRGK1,FKBP1A,CD59,RNF121,RPN1,NUS1,PYURF,RNFT1,LRRC8D,DAD1,RTCB,EI24,ARL6IP1,PIGG,SLC27A4,BCL2,PCYT2,LPCAT1,TMED2,KDELR1,PREB,FDFT1,EIF5A,PIGT,SIGMAR1,RB1CC1,ERLIN1,NSDHL,MAN1B1,ACSL3,ERO1A,RDH10,SSR2,SYVN1,VKORC1,CYB5A,RDH11,MOSPD3,DERL1,SEC31A,SCARB2,GALNT2,ORMDL2,ERGIC3,LPCAT4,SAMD8,SMPD4,MAP3K5,TMEM14A,PTDSS1,RNF139,APOL2,TMEM106C,RHOG,ATXN3,CHERP,RAC1,COPE,VTI1A,TMEM97,ADPGK,SLC35B2,LCLAT1,BCAP31,EXT2,KTN1,SEC11A,RAB21,ATP2A2,LPIN2,RPN2,BCAP29,TAP2,ANKRD13C,CYB5R1,AHCYL1,LMAN1,PDIA6,CLN6,HTRA2,MOSPD1,ACSL5,ANKLE2,UBQLN4,ATP13A1,ERMP1,SEC61B,TOR1AIP2,TMEM147,PKMYT1,DNAJA1,RAB1A,SERP1,RHBDF2,DDOST,SURF4,SEC61A1,SCAP,CERS6,SEL1L,CANT1,NCLN,ATF6,MBOAT1,REEP4,ABCA1,TMEM33,CDS2,TMX3,AGPAT3,SDF2L1,WRB,DNAJB9,HLA-A,EBP,SPPL2A,SEC24C,RRBP1,SLC35B4,YIF1B,ATG13,OSTC,CAMK2G,RNF5,TMX1,ELOVL5,MLEC,RHOA,WDR81,PNPLA8,SPPL2B,YIF1A,HLA-B,PLD3,RAB18,PDCD6,MAGT1,OSBPL8,STX18,PGRMC1,PML,ASNA1,PKD2,SPCS3,PLOD3,FAF1,ESYT2 |
| 9.631e-08 | -16.16 | GSE9988_LPS_VS_VEHICLE_TREATED_MONOCYTE_DN | MSigDB lists | GSE9988_LPS_VS_VEHICLE_TREATED_MONOCYTE_DN | 184 | 56 | 17377 | 2626 |
RHOG,SNX27,CYTIP,NCOR2,HECA,ANKRD13D,PHF23,TSC22D3,RPS6KA1,DYNLL1,SUMO2,KLF13,TWF2,PCBP1,SDHA,GIT2,PIP5K1C,PHC2,RAB8A,WDR44,FAM89B,BRI3,GLTP,CORO1A,CTDSP2,TMBIM1,PCBP2,TACC3,DNAL4,PPP1R9B,PPP1R18,TIMP2,TACC1,ATG9A,FRAT2,MAP7D1,DCLRE1C,USP22,ICMT,MPG,MYO1F,TFEB,DDX17,HHEX,CSK,ARAP1,BAZ1B,ZDHHC7,STK11,WIPI2,TMEM101,PSAP,B4GALT3,ATP6V0E1,PURA,ZNF511 |
| 9.631e-08 | -16.16 | GSE22919_RESTING_VS_IL2_IL12_IL15_STIM_NK_CELL_UP | MSigDB lists | GSE22919_RESTING_VS_IL2_IL12_IL15_STIM_NK_CELL_UP | 184 | 56 | 17377 | 2626 |
WSB2,HIVEP3,CMAS,HMGXB3,SUZ12,RRAGC,XPO7,BRIX1,TMEM165,KCMF1,BZW2,HOMER1,CLIC4,SLC1A4,DUS4L,SUV39H2,PIN1,SEPT11,NUP153,CYC1,NAP1L4,GEMIN4,MVP,SLC25A1,NOL12,EIF5A,COPS8,UBQLN4,MIOS,TSTA3,BTAF1,ZNF202,USP10,PSMG1,MRPL16,PRPF3,API5,ZDHHC3,DHX15,MAT2A,CLNS1A,PRDX1,OPTN,RDH11,DOT1L,GEMIN5,PPP2CA,TPD52L2,HINT1,PFDN4,PRPF4,KLHDC4,RTN3,NMD3,RHEBL1,FUBP1 |
| 9.631e-08 | -16.16 | GSE2770_UNTREATED_VS_IL12_TREATED_ACT_CD4_TCELL_2H_DN | MSigDB lists | GSE2770_UNTREATED_VS_IL12_TREATED_ACT_CD4_TCELL_2H_DN | 184 | 56 | 17377 | 2626 |
SEPHS2,HSPH1,TMEM184B,TRIP10,MDH2,TMEM109,OLA1,RAB23,ASAH1,GYG1,DNAJB1,UBQLN2,ATPAF1,CD320,KIAA1147,SAC3D1,GTPBP3,RPN1,RALB,GRSF1,EI24,AKR1B1,CTR9,TALDO1,SPTSSA,TFG,GTF2H2,LPCAT1,GPD1L,MTX2,DVL2,TRIM8,EID1,DENND4C,PSMA1,FBXO9,DNAJA1,VDAC1,USP21,HSPA1B,RPA1,CCDC86,CSK,PRPS2,C1orf109,SH3GLB2,KPNA2,TRIM32,GPI,SCARB1,AKNA,PLOD3,NANP,YWHAH,LRP8,TUBB |
| 9.631e-08 | -16.16 | GSE17721_0.5H_VS_4H_LPS_BMDC_UP | MSigDB lists | GSE17721_0.5H_VS_4H_LPS_BMDC_UP | 184 | 56 | 17377 | 2626 |
RHOG,LZTR1,TOMM20,TMEM203,MDH2,BABAM1,SLC2A1,HABP4,SLC39A13,NANS,SEC16A,C14orf119,RAD23A,RAP1A,STRBP,KLF16,BDH1,CTR9,MRPL48,TECR,CNOT6L,TMEM14C,NUDC,VOPP1,PPP1R18,FAM49B,HARS,FOPNL,IDH3A,RAB7A,SLC26A6,RPL6,LDHA,HTATIP2,DNAJC9,ADRB2,MCM2,VDAC1,ANLN,ABCF1,SLC50A1,NEU1,STOML2,SUPT16H,MRPL2,NSF,LIMK1,QARS,CAPN7,H2AFX,CRCP,SNX14,SLC25A39,IPO4,NUDT3,TMEM33 |
| 9.631e-08 | -16.16 | GSE3982_NEUTROPHIL_VS_NKCELL_DN | MSigDB lists | GSE3982_NEUTROPHIL_VS_NKCELL_DN | 184 | 56 | 17377 | 2626 |
TCF12,CCNC,PTMS,CHD1L,RRM1,STARD7,PXMP2,NENF,LYRM2,EXT2,BCAT2,PSMD1,CCNA2,IARS,RRBP1,MRPL34,AKR1B1,TNPO3,RPN2,COPS7B,NFU1,CENPM,MRPL40,UBE3C,ACAD8,MYBL1,F2R,FDFT1,ATP13A1,LONRF3,VHL,ABCF2,MRPL12,EZR,C1orf35,NUP155,PRMT2,MBD3,TWISTNB,CYB5A,STOML2,AKAP1,DTWD1,MAP3K4,KIF2A,FBXO21,CDCA4,SYNCRIP,GPS2,WDR7,DCAF11,IDH3B,CDK2,HEXA,CD81,PURA |
| 9.660e-08 | -16.15 | GO_NUCLEOSOME_BINDING | MSigDB lists | GO_NUCLEOSOME_BINDING | 45 | 22 | 17377 | 2626 |
HMGN1,H2AFZ,HMGN5,HMGN4,MTA2,MUM1,SMARCA4,HMGN3,ARID1A,MBD3,HMGN2,MBD2,NOC2L,H2AFY,CABIN1,ACTB,RBBP4,H3F3A,SMARCE1,HDAC2,RNF169,HP1BP3 |
| 9.660e-08 | -16.15 | FAELT_B_CLL_WITH_VH_REARRANGEMENTS_DN | MSigDB lists | FAELT_B_CLL_WITH_VH_REARRANGEMENTS_DN | 45 | 22 | 17377 | 2626 |
PPP1R2,TSPYL4,EID1,ZMYND11,LYRM1,TMX4,PARP4,GLO1,TGOLN2,GTF3A,TMEM147,MOAP1,MAGED2,HSPA4,TMED10,PSMD8,MRPL40,YY1,PLCL2,PFKP,VPS13B,ATP6V1G1 |
| 9.754e-08 | -16.14 | Mitotic Anaphase | REACTOME pathways | R-HSA-68882 | 179 | 58 | 10287 | 1696 |
MAPRE1,PTTG1,CENPF,CDCA8,NUF2,KIF2C,PMF1,SPDL1,PSMD9,LMNA,MIS12,PSMD2,PSMD1,SMC3,AHCTF1,PSMA6,BANF1,NUP107,PDS5B,ANAPC7,KNTC1,CENPM,NUP85,SEH1L,NUDC,ANKLE2,PLK1,PSMA8,TAOK1,PSMB7,PSMA1,ANAPC2,RANGAP1,AURKB,CDC23,PSMB9,PSMB3,CENPU,PSMC4,KIF2A,PPP2CA,LEMD2,CDC16,KIF18A,PPP2R5A,DSN1,CDC27,BIRC5,RPS27A,PSMD8,PSMD3,CDCA5,CENPT,NDE1,UBE2C,PSMC1,ESPL1,ANAPC4 |
| 9.778e-08 | -16.14 | GSE11864_UNTREATED_VS_CSF1_IFNG_PAM3CYS_IN_MAC_UP | MSigDB lists | GSE11864_UNTREATED_VS_CSF1_IFNG_PAM3CYS_IN_MAC_UP | 166 | 52 | 17377 | 2626 |
UBE2D3,GMFG,TSC2,PHB2,TRIM11,MAGED1,VAV2,MCCC1,VPS45,CIB1,OLA1,USP39,TGOLN2,ABHD14B,USP48,MAP1LC3B,IFT27,C12orf10,FKBP1A,CYHR1,GSTK1,C4orf3,SSBP3,GRSF1,ARHGEF1,MRPS27,PARL,SUCLG2,AFF1,TCEA1,MARCH2,GNAI2,SLC35A1,CTDSP2,HNRNPM,NTPCR,MAPRE2,SNX2,OXR1,METTL5,DNAJC9,ARID1A,PRKRA,XRCC5,SERTAD2,TBC1D17,PEX5,STK38,TBPL1,ARRB2,PDSS2,CCDC59 |
| 9.799e-08 | -16.14 | GO_PROTEIN_POLYUBIQUITINATION | MSigDB lists | GO_PROTEIN_POLYUBIQUITINATION | 240 | 68 | 17377 | 2626 |
MIB2,UBE2E2,UBR2,CUL1,ANKIB1,BIRC2,FBXO22,PSMD1,PSMA6,SIAH1,TTC3,ANAPC7,RNF19A,RLIM,PRPF19,PSMA8,RBX1,CUL3,PSMB7,TOPORS,UBE2V1,BRCA1,CDC23,CBFB,PSMB9,CDC16,RPS27A,PSMD8,TPP2,PSMD3,TRIM32,SMURF1,PSMC1,UBE2D3,TRIP12,ZFP91,SHPRH,UBE4A,PSMD9,WWP2,DTL,FBXO3,PSMD2,UBE2Q2,KLHL20,HUWE1,ZNRF2,PPIL2,BCL2,UBE3C,LRSAM1,RNF5,TNFAIP3,PSMA1,RFFL,ANAPC2,SYVN1,UBE4B,PSMB3,PSMC4,CDC27,SIAH2,UBE2C,RNF14,RNF139,CDKN2A,ANAPC4,RNF114 |
| 9.974e-08 | -16.12 | mitotic cell cycle checkpoint | biological process | GO:0007093 | 152 | 49 | 17256 | 2622 |
ZNF207,CLSPN,CENPF,TOP2B,BCL2L1,CCNB1,BLM,CNOT11,MAD2L2,FANCI,CNOT3,RFWD3,RPA2,RB1,PCNA,MDM2,CENPJ,MSH2,NABP2,NABP1,GTSE1,CDKN1B,KNTC1,CNOT6L,ATF2,CARM1,PLK1,TGFB1,PLK3,PRKDC,BTG2,TAOK1,MRNIP,BRCA1,AURKB,SOX4,CNOT9,RPS27A,E2F4,TFDP1,PML,E2F1,CNOT6,CHEK2,VPS4A,TFDP2,ZNF830,CDK2,HRAS |
| 1.000e-07 | -16.12 | CLK3 (CDC like kinase 3) | protein interactions | 1198 | 88 | 35 | 17029 | 2761 |
USP7,PRPF38B,GSPT2,JMJD6,THRAP3,SAFB2,APP,PABPC4,FAM192A,PPIG,TRA2B,TNPO3,PABPC1,LUC7L2,TERF2,SRSF10,SRPK2,CDC37,YTHDC1,BCLAF1,TOPORS,LRRC1,LUC7L,SRSF1,KPNA1,CLK3,RBMX,FKBP5,YWHAZ,KPNA2,USP11,SNRNP70,NKAPD1,YWHAH,TERF1 |
| 1.000e-07 | -16.12 | NDUFS6 (NADH:ubiquinone oxidoreductase subunit S6) | protein interactions | 4726 | 88 | 35 | 17029 | 2761 |
RMND5A,COX15,NDUFV2,NDUFS1,NDUFB6,FLOT1,NDUFA4,FAM136A,SDHA,NDUFS7,NDUFS4,BCAT2,FGFR3,NDUFV1,NDUFA2,NDUFB4,SEPT11,NDUFB9,NDUFS8,NDUFA3,MRM3,ILKAP,GID8,RAB7A,ILF3,METTL2A,NDUFA7,NDUFB1,ARMC8,BOLA3,NDUFA11,MAPK6,MPV17,NDUFS5,DNAJC30 |
| 1.010e-07 | -16.11 | GO_POSITIVE_REGULATION_OF_GENE_EXPRESSION | MSigDB lists | GO_POSITIVE_REGULATION_OF_GENE_EXPRESSION | 1673 | 328 | 17377 | 2626 |
ZNF496,H2AFZ,CXXC1,HEXB,CCNL2,CCNB1,PARK7,USF1,NOL11,DNM2,TRA2B,ECD,ZNRD1,DNMT1,SENP1,AATF,GABPA,AKT2,TOPORS,USP22,CBFB,SLC50A1,ARF4,HHEX,SMAD2,RPS27A,AXIN1,OGT,RNASEL,TRIM52,TFDP2,SMAD1,TRAF5,HDAC2,DDX58,HIVEP3,HSPH1,POLR2K,PRKAA1,EZH1,EIF2AK4,PSEN1,PSMD9,METTL3,CDC73,JMY,LMNA,CFLAR,DDRGK1,TFAP4,NUP85,PABPC1,NSUN4,TMED2,TERF2,EIF5A,FOXK1,MTA2,MYBL2,BCLAF1,ARID1A,ADRB2,CBFA2T2,ELK1,KDM3A,ABCF1,TWISTNB,CAT,SERTAD2,POLR2J,ETS2,SETD3,RBMX,CEBPG,PPP3R1,PIAS2,CDK2,RNF14,CDKN2A,RHOG,TRERF1,SF3B1,RPS6KA1,RAF1,MAGED1,ANK3,MYH9,CREBL2,APP,TERF2IP,CCNA2,SP100,LPIN2,GMEB1,MAVS,RBM15,ATF2,RPRD1B,PSRC1,BRD4,POLR2L,WBP2,E2F3,CIRBP,POLR2D,EDF1,MEF2D,ERC1,TRIM28,SERP1,SUPT16H,DDX17,TAF2,SAFB,HIPK2,STAT1,ATF6,TICAM1,TRIM32,LRP8,ATMIN,RHEBL1,POU3F2,NCOR2,MECP2,TCF3,ABHD14B,WDR5,BLM,ETS1,FOXO3,MAD2L2,GTF2F1,WWP2,CCNK,PDCD10,ITGB8,PTEN,CREB1,CITED2,NCOA2,PPP3CA,KAT2A,RFXANK,ILF3,ZP3,KLF6,PICALM,POLR2A,FADD,HGS,PRDX3,PITX1,TFDP1,HMGB2,DDX5,USF2,CD81,YWHAH,IGBP1,CCNC,ZBED3,RORB,HNRNPAB,THOC1,AGRN,GPBP1L1,FAM129A,SIRT2,MAPK14,CREM,TET3,CDC42,EIF4A3,GLIS2,ZNF639,ETV6,PIK3R2,MYBL1,MTPN,ARID4A,TRIM14,SRPK2,SP3,DEAF1,TRIM8,NCK1,VHL,MRPL12,EZR,LRP5,UBE2V1,BRCA1,EAF2,SOX4,USP21,PAF1,UBTF,E2F4,BAZ1B,ZNF268,ACTB,DVL1,CLU,CHEK2,PSMC1,FUBP1,ZNF564,PPP1R12A,PHB2,NACA,CIB1,NKD2,CHCHD2,CTCF,MEF2A,PPP3CB,THRAP3,EPHX2,RLF,ASXL2,CRLF3,ARID1B,RHBDD1,RB1,SUB1,NFATC3,MED10,SSBP3,ZNF746,BUD31,CTR9,YBX1,RBM3,MDFIC,MAML1,TRAPPC9,POLR2I,ERLIN1,LDB1,KRAS,RTF1,NFATC2IP,EIF2A,IRF5,PSMC4,RXRB,CAND1,SYNCRIP,NFIL3,NLRC5,NUP62,ZFP90,RUVBL2,SNRNP70,TOB1,SMARCD1,TCF12,PRKAB1,ASH1L,FOXM1,PLAGL2,SMARCA4,CHD1,PAIP1,RRN3,NRF1,MDM2,PSMA6,CD3EAP,PIN1,TARDBP,F2R,DVL2,PRPF19,MOSPD1,POLR2G,BTG2,RNF25,NFATC2,RPS9,SCAP,TAB2,RBL1,MAFK,STAT6,ARNTL,NCOA1,AKNA,H3F3A,MAPK1,SMAD4,BCL2L12,SLC30A9,NAT14,CTDP1,DNAJC2,EYA1,KLF13,HMGN3,IRF4,ARHGEF2,BRD7,H2AFY,SS18L1,POLR1B,STAT3,TGFB1,HMGN1,DCAF6,HMGN5,PRKDC,PRMT2,MEN1,HSPA1B,MAPK3,TFEB,TRIM26,ATAD2,TFE3,E2F1,PKD2,TAF12,RBPJ,ZMIZ1,NR2F2,HRAS,IFI16 |
| 1.043e-07 | -16.08 | NDUFS4 (NADH:ubiquinone oxidoreductase subunit S4) | protein interactions | 4724 | 77 | 32 | 17029 | 2761 |
COX15,NDUFV2,RPS2,TOMM20,NDUFS1,NUP188,NDUFA4,COX4I1,APP,NDUFS7,NDUFV1,NDUFA2,ATP2A2,NDUFB4,NDUFS8,CYC1,ATP6V0D1,VDAC2,OGDH,NDUFA7,VDAC1,SLC25A5,SDHB,ATP1A1,RPS14,COX7A2L,NDUFA11,UQCRH,ATP5F1A,NDUFS5,DNAJC30,FUBP1 |
| 1.051e-07 | -16.07 | GSE24634_TEFF_VS_TCONV_DAY5_IN_CULTURE_UP | MSigDB lists | GSE24634_TEFF_VS_TCONV_DAY5_IN_CULTURE_UP | 189 | 57 | 17377 | 2626 |
PKP4,THOC1,FOXM1,CDT1,CENPF,DBF4,OLA1,C5orf30,KIF23,JMJD6,KIF2C,BRIX1,PMVK,STMN1,SAC3D1,NAPG,GOT2,DUT,PELO,GEMIN6,KIF22,CENPM,MRPL40,LRRC59,SMC4,NUDC,PLK1,TIMM8B,TEX10,KIF15,MYBL2,RRM2,SLBP,PSMG1,RABIF,MRPL16,NUP155,GLO1,EAF2,SMC2,MCM2,C9orf40,BORA,RAD54B,ABHD5,CHCHD3,TIMM13,PLAA,UAP1,TFDP1,PPA2,LRPPRC,ACAT1,ESPL1,SSSCA1,FAF1,USP13 |
| 1.051e-07 | -16.07 | GSE2405_S_AUREUS_VS_UNTREATED_NEUTROPHIL_DN | MSigDB lists | GSE2405_S_AUREUS_VS_UNTREATED_NEUTROPHIL_DN | 189 | 57 | 17377 | 2626 |
RMND5A,GMFG,CENPF,TPX2,CDCA3,CDCA8,C5orf30,RACGAP1,NUF2,KIF2C,AP3S1,NCAPG,STMN1,FBXO5,DTL,OIP5,C1GALT1,PCNA,CCNA2,DUT,ATP13A3,SLC35B4,PRC1,LDLRAD3,SYTL3,GINS1,PHF10,TK1,RFC3,PRIM2,TSPYL4,PBK,MIER1,MKI67,CKAP2L,SLBP,RRM2,NUSAP1,CDCA2,CCNF,SHCBP1,ASF1B,CHCHD3,CDKN2AIPNL,KIF18B,ETS2,ACYP1,BIRC5,ARNTL,CEP55,CDCA5,SLC16A1,KPNA2,CNOT6,FKBP5,GLCCI1,ESPL1 |
| 1.051e-07 | -16.07 | GSE5503_LIVER_DC_VS_PLN_DC_ACTIVATED_ALLOGENIC_TCELL_DN | MSigDB lists | GSE5503_LIVER_DC_VS_PLN_DC_ACTIVATED_ALLOGENIC_TCELL_DN | 189 | 57 | 17377 | 2626 |
CCDC93,C1orf74,FGFR1OP,SMAP1,CYLD,SUZ12,HNRNPUL2,GSPT2,DNAJC24,ABCB10,ATG2B,BLM,TMEM165,REEP5,RAPGEF6,ANKIB1,PAIP1,ARL6IP6,ATG4A,KRR1,FKBP1A,LIN9,SAP130,TMEM69,PDCD10,MTMR4,ZNF639,UBA5,PARL,MAVS,MYO5A,TSHZ1,ANKLE2,SNRNP200,TCTEX1D2,FAM49B,EMB,NOL8,MTMR6,GORASP2,UHRF1BP1,GAR1,API5,TWISTNB,PLEKHF2,DTWD1,HSPA4,GOLGA4,L3MBTL3,ZNF330,CHCHD1,KBTBD7,QRSL1,ADAM9,OAZ1,CBX4,FUBP1 |
| 1.051e-07 | -16.07 | GSE36888_STAT5_AB_KNOCKIN_VS_WT_TCELL_IL2_TREATED_17H_UP | MSigDB lists | GSE36888_STAT5_AB_KNOCKIN_VS_WT_TCELL_IL2_TREATED_17H_UP | 189 | 57 | 17377 | 2626 |
COX15,LIME1,CYLD,RRP15,URB2,CAST,MRI1,TOR1AIP1,MCCC1,GTF3A,ADPGK,TMED3,CLCC1,EZH1,USP48,UBQLN2,LYRM2,RAPGEF6,DNAJB9,UBXN2A,AHCTF1,PTEN,TIMM23,BDH1,NOC2L,ANKRD13C,BCAP29,AFF1,MDFIC,MARCH2,TMEM8A,MOB1A,GM2A,SPSB3,ABCC1,NIPSNAP1,DDX28,ZDHHC18,GUK1,EMB,NOL8,LRP5,NFATC2,VKORC1,HERPUD2,XRCC5,RPL36,ALG3,PON2,TRAM2,ATP1A1,PDRG1,AEN,DTD1,PDXK,NRBP1,PFKP |
| 1.054e-07 | -16.07 | mitochondrial matrix | cellular component | GO:0005759 | 453 | 109 | 18223 | 2701 |
KARS,LYRM4,ATXN3,SUCLG1,MRPS15,MRPL39,MDH2,MCCC1,GLUD1,BCL2L1,LACTB2,CCNB1,OAT,MRPL19,PARK7,BCAT2,MRPL50,FLAD1,DECR1,PDK2,SHC1,GOT2,GRSF1,MECR,CS,MRPS27,MRPL34,HADHB,SUCLG2,TOP1MT,LRRC59,MRPL32,MRPL57,MRM2,PPIF,IDH3A,MRPL43,VDAC2,MRPL12,MCL1,OGDH,NDUFA7,VDAC1,SLC25A5,POLG2,MRPS14,PDHX,MRPL2,DAP3,MRPL55,FASTK,CHCHD1,MRPL27,PRDX5,PPA2,IARS2,MLYCD,DHTKD1,RNASEL,DHFR2,MRPL13,PITRM1,MRPL9,NDUFS1,MTERF1,MUT,MRPL42,MRPS2,TWNK,MRPS26,ATP5F1B,GFM2,FOXO3,NDUFS7,GSTK1,BDH1,MRPL54,NDUFS8,MRPL40,MRPL48,ACAD8,MRPL21,MRPL11,CREB1,MRM3,NSUN4,CARS2,DDX28,TUFM,MRPS10,NADK2,TBRG4,MRPL16,MPG,HAGH,MTHFD2,PRDX3,PARG,QARS,LRPPRC,NAXE,ACAT1,ATP5F1A,ACADM,IDH3B,MRPL3,ACSF2,PDSS2,GCSH |
| 1.079e-07 | -16.04 | GSE18893_CTRL_VS_TNF_TREATED_TCONV_2H_DN | MSigDB lists | GSE18893_CTRL_VS_TNF_TREATED_TCONV_2H_DN | 180 | 55 | 17377 | 2626 |
USP7,PKP4,GOLPH3L,TMBIM4,RPLP2,DHPS,ZDHHC8,TCF3,DHX9,UCK1,CUL1,HMGN3,GMCL1,COMMD5,PDCD7,SDHA,ABHD14A,RGS1,PNO1,GTPBP3,SEC11A,ABL2,CBWD2,PPP1R8,ZNF260,NAP1L4,SLC35C2,FBXL19,ELOF1,TDP1,LONRF3,FAM172A,TACC1,TUFM,UTP15,TUBGCP5,RTF1,BRCA1,PKMYT1,FXR1,MEN1,GUF1,BBS12,KEAP1,FNTA,POLE,RAD18,DHX16,FAM3C,ACLY,WIPI2,NDE1,TMEM14A,TAF6,HRAS |
| 1.081e-07 | -16.04 | REACTOME_S_PHASE | MSigDB lists | REACTOME_S_PHASE | 106 | 38 | 17377 | 2626 |
POLA2,MAX,CDT1,CUL1,ORC1,PSMD9,RPA2,RB1,PSMD2,PCNA,PSMD1,PSMA6,CCNA2,MCM5,CDKN1B,CDC25B,ORC3,GINS1,RFC3,PRIM2,PSMA8,PSMB7,PSMA1,CDC6,MCM2,PSMB9,RFC2,GINS4,PSMB3,PRIM1,RPA1,PSMC4,POLE,RPS27A,PSMD3,PSMD8,CDK2,PSMC1 |
| 1.081e-07 | -16.04 | SUMOylation | REACTOME pathways | R-HSA-2990846 | 110 | 41 | 10287 | 1696 |
NDC1,NSMCE4A,NUP188,RAE1,SUMO2,NUP54,CDCA8,SMC6,TOP2B,BLM,UBE2I,NUP205,PHC2,MDM2,PCNA,SMC3,NUP210,SP100,HDAC7,MTA1,NUP107,NUP153,SENP1,NUP85,SEH1L,SP3,RANGAP1,NUP155,AURKB,BRCA1,RPA1,BIRC5,NSMCE2,PIAS2,PML,NUP62,XRCC4,NUP58,CBX4,CDKN2A,AAAS |
| 1.081e-07 | -16.04 | Golgi-to-ER retrograde transport | REACTOME pathways | R-HSA-8856688 | 110 | 41 | 10287 | 1696 |
KIF3B,TMED7,COPA,DYNLL1,COPE,DCTN2,KLC1,KIF23,AGPAT3,RACGAP1,KIF2C,TMED3,RAB6A,ARF1,COPG2,COPB2,KIFC1,KIF5B,NAPG,ARF5,KIF13B,KIFAP3,KIF22,TMED2,KDELR1,DCTN1,KIF15,BICD2,RAB1A,KIF11,ARF4,KIF2A,RAB18,KIF18A,GALNT2,SURF4,KIF18B,NSF,TMED10,STX18,DYNC1LI2 |
| 1.084e-07 | -16.04 | GNF2_PA2G4 | MSigDB lists | GNF2_PA2G4 | 78 | 31 | 17377 | 2626 |
CCT2,NDUFS1,H2AFZ,NASP,MRPL39,SNRPB,METTL5,OLA1,RRM1,SLBP,MRPL16,TARS,SNRPA,CLNS1A,XRCC5,HNRNPA2B1,CHCHD3,PA2G4,PCNA,MTHFD2,IARS,MCM5,BANF1,U2SURP,LRPPRC,NUP107,CENPM,PTGES3,SNRPG,MRPL3,SSRP1 |
| 1.086e-07 | -16.04 | HIV Infection | REACTOME pathways | R-HSA-162906 | 236 | 71 | 10287 | 1696 |
CHMP2A,NDC1,PDCD6IP,NUP188,RAC1,AP1B1,PSMD1,NUP210,PSMA6,NUP107,AP1M1,AP2B1,NUP153,TCEA1,SEH1L,POLR2L,POLR2G,PSMA8,RBX1,PSMB7,ELOA,POLR2D,NUP155,CHMP2B,PSMB9,SLC25A5,SUPT16H,TAF2,CHMP4A,RPS27A,PSMD8,PSMD3,AP1S1,CHMP4B,VPS4A,XRCC4,PSMC1,AP2S1,AAAS,SSRP1,CTDP1,POLR2K,RAE1,NUP54,ARF1,PSMD9,HLA-A,NUP205,GTF2F1,CCNK,PSMD2,BANF1,GTF2H2,NUP85,POLR2I,PSMA1,RANGAP1,PACS1,POLR2A,NMT2,PSMB3,XRCC5,PSMC4,KPNA1,POLR2J,ELMO1,NUP62,TAF12,TAF6,CHMP7,NUP58 |
| 1.091e-07 | -16.03 | GSE21670_UNTREATED_VS_TGFB_IL6_TREATED_CD4_TCELL_UP | MSigDB lists | GSE21670_UNTREATED_VS_TGFB_IL6_TREATED_CD4_TCELL_UP | 171 | 53 | 17377 | 2626 |
KCTD7,CCDC93,TCF12,FAM208B,DEPDC1,CHTF18,CDCA3,NUF2,ORC1,WDR5,NCAPG,STMN1,TCF19,ZNF518A,KTN1,FANCL,PRC1,PLCL2,MYBL1,IMPA2,TACC3,HP1BP3,USP34,TK1,PSRC1,RFC3,SUGP2,CAMSAP1,CCDC34,C1orf35,WDHD1,NUSAP1,UBE4B,DCLRE1C,ANLN,HAUS8,ANKRD10,NEK1,PEX5,KIF18A,ATAD2,ACYP1,FAM110A,LUC7L3,ZNF367,NEIL3,FAM83D,E2F1,H2AFX,NDE1,SASS6,CCNB2,POLQ |
| 1.094e-07 | -16.03 | organic substance catabolic process | biological process | GO:1901575 | 1683 | 331 | 17256 | 2622 |
PDCD6IP,HEXB,CUL1,GLUD1,NHLRC3,GYG1,CCNB1,UBE2I,OAT,FBXO22,PABPC4,RPL23A,CDK5,PSMD1,RAD23B,MECR,AP2B1,PCBP2,USP34,TOPORS,USP22,AURKB,AMDHD2,CCNF,RPS27A,PSMD8,RPS14,AXIN1,ATE1,MLYCD,DHTKD1,KLHL42,SMG9,FBXL3,ARRB2,LONP2,PFKP,MUT,DHPS,GSPT2,ADO,TATDN3,KCTD17,MAN2B1,ZNRF3,PSMD9,PARN,METTL3,VPS25,CNOT3,NPLOC4,GNS,RNF121,PDXP,EXOSC7,INPP5A,ZNRF2,FBXO7,BDH1,FBXL7,PABPC1,PHKG2,CPQ,RB1CC1,MAN1B1,RPS10,USP10,RPS24,EXOSC9,PKM,PATL1,PSMB3,DERL1,KPNA1,DCAF11,USP32,CNOT6,SMPD4,GPI,HEXA,RNF139,NUDT3,ATXN3,TRERF1,UBR2,PTTG1,ADPGK,ABHD16A,NUDT19,DECR1,SIAH1,MTA1,UCHL5,DUT,LPIN2,SOCS6,NSFL1C,ANAPC7,TTC3,RNASEH2A,CLN6,GPD1L,ENPP4,SEC61B,RPL38,RNPS1,POLR2D,CUL3,CDC23,PSMB9,PPP2CA,ANKZF1,ALDH3B1,CDC16,HINT1,LSM6,NT5C3B,RNF38,RPLP1,SEL1L,TRIM32,USP13,GALK1,RPS2,MANBA,SDF2L1,UBE4A,NEIL2,TUT4,WWP2,CAPN2,PSMD2,RPL17,PTEN,CRAT,PPP1R8,FUT8,DCP1A,GTSE1,LTN1,RPL19,UPF2,CNOT6L,FBXL19,IMPA2,LYPLA2,TNFAIP3,GALC,RNASEH2C,TRIR,USP42,LDHA,RPL8,FBXO9,ANAPC2,PDE3B,RPL27A,ECH1,SH3GLB1,FBXO21,PLD3,SGSH,KEAP1,RPL32,TATDN2,ACOX1,PML,KHSRP,PPP1R11,DDX5,HMGB2,WDR91,YWHAH,ANAPC4,DDB1,FAF1,ADA2,AGRN,GNPDA1,RBM8A,MCCC1,UBE2Z,SND1,SIRT2,UBQLN2,USP48,BECN1,BIRC2,RNF103,EDC3,BCAT2,PCYOX1L,MBD4,TET3,GOT2,EIF4A3,METTL14,SLC44A1,HADHB,OGG1,PLK1,EXOSC6,RBX1,LRP5,USP21,RPL37,NAGLU,ARRDC1,CHEK2,VPS4A,CLU,CLN3,NUDT11,NGLY1,RPS26,PSMC1,CAPN1,UBE2D3,RMND5A,RPS15,TMUB1,UBXN1,SDC2,RPL15,PM20D2,THRAP3,CNOT11,EPHX2,RHBDD1,PRPF18,DTL,SLC27A4,AHCY,ACAD8,ZRANB1,LRSAM1,ABHD2,ERLIN1,NUDT4,RPL6,GBA,PSMA1,UBE4B,SYVN1,ARMC8,ISG15,RPL36,PSMC4,CDC27,KLHL15,SIAH2,DNPH1,CTSA,ECPAS,USP7,CYLD,RPLP2,PAIP1,RAD23A,RPL11,USP5,CSDE1,UBXN2A,PSMA6,MDM2,KIF14,EXOSC1,GM2A,SPSB3,HTRA2,RLIM,CHP1,PRPF19,SNX25,RPL29,RPL35,POLR2G,PSMA8,HPDL,PPT1,RAB7A,PSMB7,OGDH,EDEM2,TOLLIP,RPS9,USP36,BTBD1,RPSA,DNAJC10,IDE,UBXN2B,PSMD3,ARNTL,CHMP4B,SCARB1,USP11,SMURF1,LTA4H,AP2S1,CHID1,TRIP12,CHAC2,CSNK1A1,DNAJB9,CTSS,KLHL20,PELO,ABCD1,RNF5,TGFB1,SAMD4B,RFFL,WDR81,PNPLA8,HAGH,NEU1,HSPA1B,CNOT9,CTSL,UPF1,PLAA,CTBS,USP20,ACAT1,ACADM,TATDN1,UBE2C,PGAM1,SAT2,GCSH |
| 1.100e-07 | -16.02 | TIPRL (TOR signaling pathway regulator) | protein interactions | 261726 | 46 | 23 | 17029 | 2761 |
SRM,LARS,TCTEX1D2,UROD,CUL3,COMMD4,APP,PRDX1,LMNA,PPP2CA,IARS,EIF4A3,HUWE1,SH3BP1,UCHL5,CORO1C,TPP2,MSH2,PPP6C,PTPDC1,PPP6R3,IGBP1,MCMBP |
| 1.118e-07 | -16.01 | Rpl35 (ribosomal protein L35) | protein interactions | 66489 | 248 | 73 | 17029 | 2761 |
BCCIP,DDX47,EIF3D,YTHDC2,YTHDF3,SND1,RPL11,RPL23A,KRR1,HNRNPA2B1,MRPL50,DECR1,PA2G4,FBXL6,TIMM23,PDCD2,CDC37,SRP72,EXOSC6,RFC3,NSUN2,CIRBP,RIOX2,LRRC8A,RFC2,LSG1,RPS9,EIF3G,RPSA,EIF3H,EIF3A,ZMYM3,SUPT16H,KIF2A,EIF3K,RPS14,BTF3,FAU,ZNF598,SSRP1,RPS15,RPS2,DHX9,NKRF,HDGFL2,BLM,HMG20A,CNOT3,MED10,RPL17,BANF1,BTF3L4,RTCB,RBM3,RPL19,MRPL48,NSUN4,EIF3L,FOCAD,PSPC1,DHX29,ILF3,GTPBP4,RPS10,RPS24,USP10,MPG,RPL27A,RPL36,RPL32,CCDC86,IMPDH1,ZC3HAV1 |
| 1.126e-07 | -16.00 | regulation of chromosome organization | biological process | GO:0033044 | 317 | 84 | 17256 | 2622 |
ZNF207,USP7,KMT2E,PTTG1,RMI2,CCNB1,BECN1,TERF2IP,HNRNPA2B1,NEK6,AKAP8,NOC2L,CHTOP,DNMT1,TACC3,PLK1,CCT2,ERCC1,EID1,KAT7,TLK1,MKI67,WBP2,CUL3,WDHD1,CDC6,AURKB,BRCA1,CDC23,MCM2,TRIM28,IWS1,MAP3K4,PAF1,NSMCE2,UHRF2,OGT,XRCC3,H3F3A,GEN1,SLF1,MAPK1,POT1,SMAD4,TRIP12,MECP2,CDT1,CENPF,CTCF,PARN,MAD2L2,RB1,NABP2,ZNF335,AXIN2,BRD7,CTR9,H2AFY,MCPH1,TERF2,TGFB1,ZFP64,KAT2A,NEK7,MIER1,RTF1,KDM3A,CCT8,XRCC5,MAPK3,UPF1,CDC27,ATAD2,PARG,CDCA5,PML,KMT2B,RUVBL2,UBE2C,PARP10,TERF1,SLF2,ESPL1,ANAPC4 |
| 1.140e-07 | -15.99 | KAECH_NAIVE_VS_DAY8_EFF_CD8_TCELL_DN | MSigDB lists | KAECH_NAIVE_VS_DAY8_EFF_CD8_TCELL_DN | 194 | 58 | 17377 | 2626 |
NDUFV2,SMAP1,TXN,H2AFZ,ANXA6,GNPDA1,SEC61G,PTTG1,RACGAP1,KIF2C,TCF19,STMN1,REEP5,REPS1,HLA-A,CDKN2C,RPA2,CLIC4,MBD2,RRBP1,PRC1,FAM89B,KIF22,NDUFB9,MDFIC,F2R,S100A6,TACC3,BAK1,MAPRE2,TSPAN31,MKI67,RRM2,MAP7D1,NUSAP1,KRTCAP2,KIF11,ECH1,PRDX1,MYO1F,NUCB1,IDE,AHNAK,BIRC5,PSMD8,CDCA5,DBI,MRPL27,ITGB1,ACTB,HMGB2,BTF3,CCNB2,CHPT1,AP2S1,ATP6V0E1,VPS29,PFKP |
| 1.158e-07 | -15.97 | KONG_E2F3_TARGETS | MSigDB lists | KONG_E2F3_TARGETS | 94 | 35 | 17377 | 2626 |
DEPDC1,CENPF,TPX2,CDCA3,RACGAP1,NUF2,KIF2C,CCNB1,NCAPG,CCNA2,PRC1,RPRD1B,TACC3,PLK1,TK1,NASP,PBK,RAD51AP1,MKI67,E2F3,CDC6,NUSAP1,SMC2,BRCA1,CCNF,KIF11,SHCBP1,ASF1B,PRIM1,RBL1,DCK,CDCA5,H2AFX,HMGB2,UBE2C |
| 1.176e-07 | -15.96 | GO_AUTOPHAGY | MSigDB lists | GO_AUTOPHAGY | 369 | 94 | 17377 | 2626 |
CHMP2A,PRKAB1,TOMM20,TMEM203,DYNLL1,ALKBH5,VTI1A,RRAGC,SIRT2,UBQLN2,MAP1LC3B,BECN1,STAM,PARK7,EPM2A,FANCL,ATG3,DNAAF2,TXLNA,NDUFB9,CISD2,C8orf59,DRAM2,MLST8,CDC37,ULK3,UBQLN4,ATG9A,SNRPB,RAB7A,CRNKL1,RAB1A,CHMP2B,VDAC1,TOLLIP,RHEB,OPTN,TBC1D17,CHMP4A,RAB24,RPS27A,TOMM6,STK11,CHMP4B,VPS4A,CLN3,SMURF1,PFKP,USP13,MRPS2,PHF23,DAP,PRKAA1,RAB23,LAMTOR3,ATG2B,PSEN1,VPS25,ATG4A,RFWD3,MEX3C,SLC1A4,VMP1,RIMS3,FBXO7,EI24,ANXA5,ATG13,LRSAM1,PACS2,ZNF189,TMEM39A,RB1CC1,MRPS10,USP10,KCNQ1,TOMM40,MARK2,SH3GLB1,TFEB,MFN2,PI4K2A,MTMR3,HGS,SNAP29,COX8A,SLC25A19,MDH1,CTSA,WIPI2,SNX14,CDKN2A,IFI16,SNAPIN |
| 1.180e-07 | -15.95 | GSE26030_UNSTIM_VS_RESTIM_TH1_DAY5_POST_POLARIZATION_DN | MSigDB lists | GSE26030_UNSTIM_VS_RESTIM_TH1_DAY5_POST_POLARIZATION_DN | 185 | 56 | 17377 | 2626 |
HIVEP3,H2AFZ,TMEM184B,AGRN,CASP6,TOR3A,ANKH,CUTA,ARID5A,SLC25A12,NIT2,SIRT2,ATP6V1B2,TMEM165,APH1B,GLRX3,HMG20A,CAPN2,TNS3,SUB1,RCSD1,PIK3R2,ANXA5,SPTSSA,CTDSP2,S100A6,MYO5A,GPX4,ANKLE2,AMPD2,SEC61B,PTPN18,TCTEX1D2,KIAA0040,PPP1R21,WIPF1,ESYT1,EIF2A,PRKRA,SERP1,FAS,MAN2A2,INF2,AHNAK,TTC13,SEC61A1,TMED10,QARS,TFDP1,ACAT1,RNASEL,BTF3,IGBP1,XRCC4,MZT2B,HIGD2A |
| 1.180e-07 | -15.95 | GSE14000_TRANSLATED_RNA_VS_MRNA_DC_UP | MSigDB lists | GSE14000_TRANSLATED_RNA_VS_MRNA_DC_UP | 185 | 56 | 17377 | 2626 |
KCTD7,SARNP,NOP2,RRP15,RAE1,ACTR3,GSPT2,RACGAP1,ARGLU1,EBNA1BP2,OAT,RAB11A,CDC73,MCTS1,GART,PSMA6,IARS,UCHL5,RBM34,GRSF1,AKAP8,NUP107,ZNF326,TTC4,POLR1B,TFG,MRPL32,RHOBTB3,RFC3,POLR2G,FOXK1,LDHA,ELP4,NUSAP1,GORAB,MRPL16,PLEKHM3,ARID1A,BUD13,DDX39A,FOXRED1,GAR1,PATL1,TARS,TWISTNB,HAUS8,ANKZF1,NIP7,PFDN4,CORO1C,DUSP11,ATP6V1C1,MRPL13,PGAM1,XRCC4,ZC3HC1 |
| 1.180e-07 | -15.95 | GSE15330_MEGAKARYOCYTE_ERYTHROID_PROGENITOR_VS_PRO_BCELL_UP | MSigDB lists | GSE15330_MEGAKARYOCYTE_ERYTHROID_PROGENITOR_VS_PRO_BCELL_UP | 185 | 56 | 17377 | 2626 |
RAB14,GMFG,SUCLG1,ANKH,CDCA3,CERK,KLF13,COX4I1,TMED3,MAP1LC3B,FAM8A1,CDK5,RB1,APLP2,NEK6,SIAH1,KIFAP3,KIF22,TFG,CLTB,TMEM14C,NTPCR,FTL,POLR2I,PPP1R18,EID1,MYBL2,KCTD20,ATP6V0A1,LRRC8A,NUSAP1,TOPORS,PACS1,GLO1,AURKB,USP22,CCNF,CYFIP2,SMAP2,CYB5A,MAPK3,DERL1,RAB18,FBXO21,TMEM41A,RPS14,HIPK2,COX7A2L,IMPDH1,KPNA2,TMEM101,SMAD1,SMAD4,ATP6V0E1,LONP2,TSPAN5 |
| 1.180e-07 | -15.95 | GSE23568_ID3_KO_VS_WT_CD8_TCELL_UP | MSigDB lists | GSE23568_ID3_KO_VS_WT_CD8_TCELL_UP | 185 | 56 | 17377 | 2626 |
NDUFA5,GCLM,GOLIM4,TXN,RWDD1,POLR2K,SEC61G,UFC1,CDT1,UBXN1,PTTG1,UCK2,LAGE3,CDCA8,RACGAP1,GYG1,BLM,STMN1,TCF19,MIEN1,POLR3K,DTL,SLC31A1,IMPAD1,IMPA2,TACC3,TXNL1,TIMM8B,RFC3,ASPM,POLR2D,MKI67,NUSAP1,CDC6,ANLN,RFC2,KIF11,PSMB3,ASF1B,ECH1,RDH11,MYO1F,GEMIN5,AMZ2,HHEX,BIRC5,SNAP23,MRPL27,TFDP1,CDCA5,HMGB2,CHEK2,RGL1,SASS6,CCNB2,RPS26 |
| 1.180e-07 | -15.95 | GSE23114_PERITONEAL_CAVITY_B1A_BCELL_VS_SPLEEN_BCELL_DN | MSigDB lists | GSE23114_PERITONEAL_CAVITY_B1A_BCELL_VS_SPLEEN_BCELL_DN | 185 | 56 | 17377 | 2626 |
MIF,SRM,EXOC3,NCOR2,HSPH1,GCLM,IMMT,TXN,SCAMP3,SRGN,NCKAP1,FKBP2,DCUN1D4,CFLAR,RPA2,FARSA,PA2G4,HOMER1,PSMD1,MTA1,ZNF200,PDCD2,RPN2,SS18L1,CPSF4,LPCAT1,TIPARP,METTL1,SP3,MLEC,POLR2G,AATF,TSTA3,MAPKAPK3,PPT1,AMD1,ABCF2,HNRNPF,ADSL,NUTF2,CAPZA2,SLC25A5,PSMB3,FADD,ALG3,PPP2CA,HSPBP1,CCDC86,STT3A,ELMO1,TIMM17A,HPS5,DBI,SSSCA1,GCSH,SSRP1 |
| 1.180e-07 | -15.95 | GSE17721_LPS_VS_GARDIQUIMOD_0.5H_BMDC_DN | MSigDB lists | GSE17721_LPS_VS_GARDIQUIMOD_0.5H_BMDC_DN | 185 | 56 | 17377 | 2626 |
USP7,DNAJC2,TRIM41,TMUB1,PARP12,SF3B1,SUZ12,ANKH,SNX15,C19orf25,FAM76A,CHIC2,AP1B1,EPHX2,LCLAT1,KCMF1,RTKN,CDKN2C,RAP1A,SMC3,MTA1,RAB4A,MEA1,TIMELESS,CRY2,MDFIC,SLC12A2,LYPLA2,HNRNPM,RPAP3,TRIM8,PIGT,RBX1,NEK7,SELPLG,KAT7,WBP2,RPL6,ILF3,TBRG4,NFATC2IP,FXR1,BSDC1,PRDX1,GOLGA4,CCDC6,WNT5B,PSMD3,STK11,CHMP4B,SLC22A23,NUDT11,TSTD2,RPS26,EYA2,NUDT3 |
| 1.180e-07 | -15.95 | GSE10240_IL22_VS_IL17_STIM_PRIMARY_BRONCHIAL_EPITHELIAL_CELLS_UP | MSigDB lists | GSE10240_IL22_VS_IL17_STIM_PRIMARY_BRONCHIAL_EPITHELIAL_CELLS_UP | 185 | 56 | 17377 | 2626 |
WSB2,SEPHS2,CCDC93,GOLIM4,MPHOSPH8,AGRN,SUZ12,DAP,HNRNPUL2,FAM76A,B4GALT1,NKRF,ATG2B,CHAC2,USP48,S1PR2,RAPGEF6,CDC73,PAIP1,TFRC,FBXO22,ATG4A,MAT2B,MLX,GOT2,SIVA1,MBD2,UBA5,HADHB,PARL,RP2,FAM76B,MCPH1,ZNF770,NCOA2,ERMP1,FAM49B,RBX1,GMFB,RNPS1,CCDC34,CDC6,GORASP2,EIF4H,TWISTNB,GLOD4,YIF1A,DTWD1,FBXO28,CHCHD1,HNRNPH3,DBI,GPI,RBBP4,ZBTB11,PFKP |
| 1.180e-07 | -15.95 | GSE41867_NAIVE_VS_DAY30_LCMV_ARMSTRONG_MEMORY_CD8_TCELL_UP | MSigDB lists | GSE41867_NAIVE_VS_DAY30_LCMV_ARMSTRONG_MEMORY_CD8_TCELL_UP | 185 | 56 | 17377 | 2626 |
GLT8D1,SARNP,MRPL9,SYS1,CASP6,GNE,SLC25A12,NDUFA4,GYG1,IFT27,RBM4,APOPT1,COPB2,NDUFS4,FLAD1,NUDT19,FANCL,SNRNP25,NVL,TIMM23,CENPJ,ARF5,NUP107,PDCD2,ANAPC7,TCEA1,MINPP1,ORC3,MCMBP,ELOF1,NUDC,RPAP3,MAPRE2,ERMP1,SEPT9,GABPA,CDC123,TIMMDC1,TSPYL4,CYP20A1,CRNKL1,TUFM,ZNF574,ATXN1,DCUN1D5,NDUFA7,FOXRED1,OPTN,HINT1,STT3A,CERS6,CTBS,SEL1L,RBBP4,ZMAT3,GPATCH4 |
| 1.189e-07 | -15.94 | nuclear envelope | cellular component | GO:0005635 | 454 | 109 | 18223 | 2701 |
CHMP2A,NDC1,NUP188,TOR1AIP1,TMEM109,TMEM97,AGFG1,BCL2L1,UBE2I,MRPL19,APP,PRNP,TERF2IP,DST,FANCL,ANKLE1,AHCTF1,NUP210,SNUPN,UTP18,MTA1,INTS1,NUP107,TRA2B,TNPO2,NUP153,RBM15,LRRC59,SENP1,SEH1L,DCTN1,CPNE1,NXT1,MTMR6,HTATIP2,NUP155,TOR1AIP2,BICD2,NUTF2,ERBIN,TXNL4A,TMEM201,CERS6,STAT6,NRM,CHMP4B,ATF6,KPNA2,SMAD1,AAAS,TUBB,ANXA11,ZC3HC1,TMEM33,NXT2,INTS2,DNAJC2,NEMP2,DNAJB2,RAE1,CENPF,RRM1,NUP54,BRAP,GMCL1,AGPAT3,XPO7,PSEN1,QSOX2,NUP205,LMNA,EBP,DTL,MLX,NDUFB4,BANF1,EI24,RTCB,TNPO3,BCL2,YBX1,GLE1,MVP,TNRC18,NUP85,S100A6,EIF5A,SIGMAR1,RB1CC1,GTPBP4,RANGAP1,ABCF1,MATR3,NPIPA1,MAPK3,CBX3,LEMD2,KPNA4,PCM1,KPNA1,NSMF,OSBPL8,LRPPRC,AEN,NUP62,CHMP7,NUP58,IPO4,FAF1 |
| 1.232e-07 | -15.91 | RPLP2 (ribosomal protein lateral stalk subunit P2) | protein interactions | 6181 | 136 | 47 | 17029 | 2761 |
COX5B,RPS15,RPS2,CYLD,EWSR1,RPLP2,MECP2,RPL15,CUL1,NANS,TUBGCP2,RPL11,RPL23A,PA2G4,GRK2,PTEN,RBM34,ZNF746,RPL19,PABPC1,SRPK2,RPL35,DDX24,MRPL12,RPS10,CUL3,RPL8,RPL38,RPL6,RPS24,BRCA1,MCM2,RPL27A,RPS9,RPSA,CAND1,RPL36,DGCR8,RPS14,RPLP1,H2AFX,COPS6,RRS1,CDK2,ARRB2,CD81,RPS26 |
| 1.232e-07 | -15.91 | FZR1 (fizzy and cell division cycle 20 related 1) | protein interactions | 51343 | 136 | 47 | 17029 | 2761 |
UBE2D3,CLSPN,FOXM1,EYA1,CDT1,C16orf87,PTTG1,TPX2,CDCA3,CUL1,RACGAP1,SIRT2,CCNB1,MAD2L2,FBXO5,MOAP1,CDK5,RB1,CCNA2,PTEN,KMT5A,ANAPC7,MCPH1,TACC3,PLK1,STAU1,TK1,PRKDC,VHL,E2F3,RRM2,ANAPC2,CDC6,AURKB,DNAJA1,CDC23,CCNF,CDC16,CDC27,E2F1,CHEK2,CDK2,SMURF1,UBE2C,DDB1,ZC3HC1,ANAPC4 |
| 1.249e-07 | -15.90 | ARRB2 (arrestin beta 2) | protein interactions | 409 | 379 | 101 | 17029 | 2761 |
RPLP2,SF3B1,RAF1,MYH9,CSNK2A1,AP1B1,SDHA,PABPC4,RPL11,SF3B2,HNRNPA2B1,UTP25,MDM2,CDC42,AP2B1,RPN2,AHCYL1,MOB1A,CLTB,SENP1,DVL2,CFL1,SRPK2,CPNE1,ARHGAP17,RPL35,NSUN2,MRPL43,CUL3,HNRNPF,PFKFB3,TRIM28,DHX15,CLNS1A,AFDN,RAD18,HNRNPR,TAB2,RPS27A,LIMK1,STK38,STAT1,RPLP1,H2AFX,PRPF4,ACTB,MAPK1,CAPN1,HDAC2,PRPF4B,PPP1R12A,CENPF,RPL15,CDK13,THRAP3,EIF2AK4,HDGFL2,SCYL2,NDUFS7,TFAP4,ERH,MED8,EFTUD2,CTPS1,CAPZA1,YBX1,RPL19,POLR1B,PTGES3,CENPM,MAP3K14,FBL,PABPC1,HNRNPM,SPTAN1,CYTH1,RPL6,ILF3,RTF1,ARHGEF12,BCLAF1,RANGAP1,CAPZA2,ADRB2,PKM,TWISTNB,MAPK3,HSPA1B,RPA1,RPL36,XRCC5,NAP1L1,HGS,KPNA4,CSK,DDX5,ZRANB2,TCOF1,MAP3K5,YWHAH,HIPK3 |
| 1.272e-07 | -15.88 | CEP152 (centrosomal protein 152) | protein interactions | 22995 | 108 | 40 | 17029 | 2761 |
NDUFA5,FGFR1OP,LUZP1,DYNLL1,RAE1,ACTR3,VPS45,RRM1,NCKAP1,HAUS2,TUBGCP2,CNOT3,LYAR,DLG5,CENPJ,KIF14,TXLNA,GPATCH1,RPF2,CEP63,TP53BP2,POC5,SAMD4B,MLEC,CCDC138,MAP4K4,ADSL,PSMG1,SMC2,ERC1,ECH1,IRF5,HAUS8,CNOT9,PCM1,CSK,MYO9A,SASS6,YWHAH,ECPAS |
| 1.283e-07 | -15.87 | GSE9650_EXHAUSTED_VS_MEMORY_CD8_TCELL_DN | MSigDB lists | GSE9650_EXHAUSTED_VS_MEMORY_CD8_TCELL_DN | 190 | 57 | 17377 | 2626 |
ANXA6,ADD1,SUCLG1,WDR13,UFC1,MOGS,C5orf30,EBNA1BP2,TWF2,ETS1,MIEN1,MAP1LC3B,VPS25,PARK7,GOLM1,VAV1,MRPL50,RPN1,C18orf32,EXOSC7,SRI,FAM89B,HADHB,ANXA5,BCL2,TAGLN2,RNASEH2A,FBL,GM2A,CDC37,ADCY7,ELOVL5,RHOA,TSPAN31,RNPS1,LDHA,SMU1,GLO1,PACS1,ADRB2,ICAM2,API5,KLF6,PRPSAP1,CCT8,MAT2A,XRCC5,YIF1A,AXIN1,STK38,GALNT10,HEXA,OAZ1,EYA2,TOB1,PFKP,TUBB |
| 1.283e-07 | -15.87 | GSE1460_CD4_THYMOCYTE_VS_NAIVE_CD4_TCELL_CORD_BLOOD_UP | MSigDB lists | GSE1460_CD4_THYMOCYTE_VS_NAIVE_CD4_TCELL_CORD_BLOOD_UP | 190 | 57 | 17377 | 2626 |
GLT8D1,IMMT,DNAJB2,SF3B1,CUL1,TM9SF3,USP39,LANCL1,POMP,FAM136A,STMN1,MAPK14,CMTM6,TFRC,COPB2,SSR1,INTS7,ATG3,UCHL5,RIMS3,XRCC2,PPP4R1,NUP107,MSH2,TARDBP,TP53BP2,TDP1,ERMP1,KLF10,AATF,LAP3,GABPA,WDR1,CRNKL1,ITM2A,GORASP2,SEPT7,MCFD2,PTTG1IP,VDAC1,TTC33,POLR2A,BTBD1,RAD54B,CBX3,TPD52L2,OSBPL8,TIMM17A,CORO1C,PGRMC1,IARS2,MDH1,CNOT6,XRCC3,SRSF3,HEXA,SMURF1 |
| 1.283e-07 | -15.87 | GO_NEGATIVE_REGULATION_OF_MITOTIC_CELL_CYCLE | MSigDB lists | GO_NEGATIVE_REGULATION_OF_MITOTIC_CELL_CYCLE | 190 | 57 | 17377 | 2626 |
ZNF207,HECA,GPR132,CLSPN,CENPF,PTTG1,CSNK2A1,SMARCA4,TOP2B,BCL2L1,BLM,CCNB1,CDC73,MAD2L2,CNOT3,FANCI,RFWD3,RPA2,RB1,MDM2,PCNA,CCNA2,PTEN,CENPJ,FBXO7,MSH2,BRD7,CDKN1B,GTSE1,BCL2,KNTC1,CNOT6L,ATF2,CTDSP2,CARM1,PLK1,TGFB1,PLK3,TIMP2,BTG2,PRKDC,SOX4,PRMT2,RBM38,RPS27A,E2F4,TFDP1,PML,E2F1,PKD2,CNOT6,CHEK2,ZNF830,TFDP2,CDK2,TERF1,HRAS |
| 1.283e-07 | -15.87 | GSE46606_IRF4HIGH_VS_WT_CD40L_IL2_IL5_DAY1_STIMULATED_BCELL_UP | MSigDB lists | GSE46606_IRF4HIGH_VS_WT_CD40L_IL2_IL5_DAY1_STIMULATED_BCELL_UP | 190 | 57 | 17377 | 2626 |
TCF12,NAT9,NDUFS1,TMEM203,SHPRH,TCF3,CDT1,UROD,CCM2,FAM76A,ABHD14B,EIF2AK4,UBQLN2,C2orf49,DUSP22,RUFY1,ARID1B,ANKRD26,GTPBP3,APLP2,CCP110,TBC1D22A,SSBP3,MEA1,RNF26,CLN6,TNRC18,N4BP2,NSUN4,RNF169,TACC3,ALDH9A1,PREB,ADCY7,NIPAL3,SNRNP200,NASP,GALC,CREG1,RAB7A,TMEM126B,PPP1R21,OXR1,SLC26A6,PDE3B,MBD3,BTBD1,ANKRD46,GPR137,IDE,TXNDC16,LMBR1,ZDHHC7,PPP5C,HEXA,ATP6V0E1,ANXA11 |
| 1.292e-07 | -15.86 | regulation of mitotic nuclear division | biological process | GO:0007088 | 162 | 51 | 17256 | 2622 |
ZNF207,CHMP2A,PDCD6IP,PHB2,CDT1,CENPF,PTTG1,CDK13,SIRT2,CCNB1,BECN1,MAD2L2,FBXO5,PDXP,RB1,SMC3,NEK6,PIN1,H2AFY,CDKN1B,KNTC1,TACC3,PLK1,TGFB1,PPP1R9B,CUL3,MKI67,CDC6,NUSAP1,LRP5,PKMYT1,ANLN,CDC23,CHMP2B,KIF11,BORA,DAPK3,HSPA1B,CDC16,CDC27,NSMCE2,CDCA5,NUP62,XRCC3,CHMP4B,GEN1,SLF1,UBE2C,ESPL1,SLF2,ANAPC4 |
| 1.295e-07 | -15.86 | VHL (von Hippel-Lindau tumor suppressor) | protein interactions | 7428 | 346 | 94 | 17029 | 2761 |
SARNP,TXN,HNRNPAB,IVNS1ABP,ARID2,SLC2A1,CSNK2A1,KIF2C,APP,PARK7,RPL11,HNRNPA2B1,SAP130,IARS,PIN1,CDKN1B,TARDBP,DVL2,CCT2,RHOBTB3,POLR2G,RBX1,AKT2,VHL,ELOA,RRM2,DNAJA1,PBRM1,CHMP2B,TRIM28,RPS9,RPSA,DDX17,PPP2CA,HSPA4,HNRNPR,RPS14,STK38,CAB39,ACTB,CHEK2,CLU,SMURF1,CCDC59,PARD3,HDAC2,MIF,KIF3B,PPIB,RPS2,TRIP12,RHOC,NKRF,LANCL1,YY1AP1,FASTKD3,FGFR3,PTEN,HUWE1,KIFAP3,KNTC1,TAGLN2,HNRNPM,MOB4,EIF5A,TRAFD1,RB1CC1,PRKDC,ILF3,RIT1,ADRB2,ARID1A,CCT8,TARS,PSMB3,PRDX1,POLR2A,CBX3,XRCC5,TSC1,GOLGA4,CAPN7,E2F1,USP20,DDX5,PLOD3,RBBP4,SNRNP70,CDK2,HNRNPDL,SAT2,RNF139,CDKN2A,EGLN1 |
| 1.303e-07 | -15.85 | CNTRL (centriolin) | protein interactions | 11064 | 157 | 52 | 17029 | 2761 |
CEP170B,PRPF38B,LUZP1,RAB11B,HAUS4,CCNB1,PRKACA,HAUS2,TUBGCP2,NUP205,COPB2,ABRACL,ANKRD28,ANKRD26,DLG5,RAB8A,RAB35,KIF14,SEC24C,TXLNA,ZNF326,DNM2,GTSE1,GPATCH1,ARHGEF2,TP53BP2,TTLL12,MTPN,LUC7L2,PLK1,CSRP1,CCDC138,RAB7A,MAP4K4,AURKB,TANC1,RAB5B,ERC1,DAPK3,HSPA1B,HAUS8,MAP3K4,UPF1,TRIM26,PCM1,SPATA2,CCDC14,ODF2,MAPK6,EXOC4,IDH3B,YWHAH |
| 1.303e-07 | -15.85 | GO_REGULATION_OF_TRANSFERASE_ACTIVITY | MSigDB lists | GO_REGULATION_OF_TRANSFERASE_ACTIVITY | 912 | 195 | 17377 | 2626 |
CCNC,FGFR1OP,TXN,TSC2,NF1,CUL1,CCNL2,CCNB1,S1PR2,UBE2I,MAPK14,PARK7,ZER1,CDK5,CALM2,CDKN2C,RAP1A,PSMD1,CDC42,PIK3R2,CDC25B,CDC37,COPS8,BAK1,PLK1,NCK1,GMFB,LRP5,TOPORS,CDC6,AURKB,DCUN1D5,PRPSAP1,RFC2,MAP3K4,HHEX,RPS27A,PSMD8,LIMK1,AXIN1,SOCS4,CAB39,ADAM9,STK11,CLU,DVL1,PSMC1,POT1,PDCD4,HSPH1,GMFG,CLSPN,GORASP1,CHTF18,PRKAA1,VAV2,GADD45G,CIB1,RGS2,PSMD9,PSEN1,TFAP4,RB1,FBXO7,MDFIC,PIK3IP1,MVP,GNAI2,SOCS5,MAPKAPK3,LDB1,GBA,GTPBP4,PSMA1,KRAS,MAP4K3,ADRB2,MAP2K2,PSMB3,PSMC4,MASTL,TSC1,MBIP,CDC27,GOLGA2,CSK,DUSP3,NLRC5,NUP62,MAP3K5,CDK2,ALS2,CDKN2A,BCCIP,PRKAB1,TRAF7,RAF1,MAGED1,RAC1,TPX2,DUSP22,LYN,PRKACA,APP,CRKL,PSMA6,CCNA2,SHC1,RALB,NVL,PIN1,KIF14,ADCY9,SOCS6,CDKN1B,ANAPC7,F2R,ABI1,CDK12,DVL2,ADCY7,CCT2,RFC3,PSRC1,PSMA8,PSMB7,CUL3,ELP4,PKMYT1,DNAJA1,CDC23,RAB1A,PSMB9,SOCS7,PPP2CA,CDC16,PPP2R5A,TAB2,RBL1,PSMD3,CORO1C,STK38,GADD45B,RPLP1,XRCC3,MAPK1,GEN1,LRP8,MIF,RPS2,ZFP91,AKT1S1,BLM,DCUN1D4,MAD2L2,FBXO5,PTPN2,CCNK,PSMD2,FGFR3,PDCD10,PTEN,PTPN11,FEM1B,H2AFY,MAP3K14,TGFB1,PDPK1,TELO2,ADAM17,RHOA,TNFAIP3,NEK7,PRKAR1B,JTB,ANAPC2,MEN1,ZP3,MARK2,MAPK3,SH3BP5,HGS,PRDX3,GPS2,OSBPL8,PML,PKD2,NR2F2,UBE2C,CD81,HIPK3,HRAS,TERF1,FAF1,ANAPC4 |
| 1.305e-07 | -15.85 | EPRS (glutamyl-prolyl-tRNA synthetase) | protein interactions | 2058 | 120 | 43 | 17029 | 2761 |
KARS,CYLD,SF3B1,SUZ12,TRMT6,CUL1,ATP6V1B2,SDHA,VPS25,CDC73,RPL23A,RPA2,PSMD2,CDC42,IARS,HUWE1,AHSA1,TXLNA,DUS2,CRY2,RPN2,EEF1D,SRSF10,STAU1,LARS,IDH3A,RPL6,CUL3,KRAS,BRCA1,VDAC1,RPA1,C1orf131,SYNCRIP,TFE3,QARS,DDX5,NCLN,CDK2,NMD3,PFKP,TUBB,DDX42 |
| 1.324e-07 | -15.84 | GSE14769_40MIN_VS_360MIN_LPS_BMDM_UP | MSigDB lists | GSE14769_40MIN_VS_360MIN_LPS_BMDM_UP | 181 | 55 | 17377 | 2626 |
SEPHS2,POLA2,GOLIM4,HABP4,VPS45,LAGE3,SIKE1,GLUD1,ABCB10,MXD4,ITGB5,STMN1,SAC3D1,MCTS1,SEC11A,ERH,C1GALT1,RPL17,THAP4,LRRC8D,DUT,TBC1D14,NAA50,EFCAB11,BCL2,ANAPC7,AHCY,CPSF4,LRSAM1,MTX2,S100A6,KCNAB2,NUDC,CARS2,SRPK2,NTPCR,NQO2,VDAC2,BOLA1,ARHGDIB,AMDHD2,MCFD2,SLC50A1,ARHGAP15,MKNK1,WDR11,NEIL3,COX8A,E2F1,DHTKD1,ATE1,CTSA,ANP32E,IDH3B,CPEB2 |
| 1.324e-07 | -15.84 | GSE15330_MEGAKARYOCYTE_ERYTHROID_PROGENITOR_VS_PRO_BCELL_DN | MSigDB lists | GSE15330_MEGAKARYOCYTE_ERYTHROID_PROGENITOR_VS_PRO_BCELL_DN | 181 | 55 | 17377 | 2626 |
SEPHS2,NDUFV2,MUT,FAM207A,PRKCSH,MDH2,LAMTOR3,PTP4A3,CHAC2,GGA2,AP3S1,PARN,CUTC,SDHA,VPS25,HDDC2,SSR1,CDKN2C,FKBP1A,PCNA,EIF4A3,TIMELESS,NDUFS8,UBE3C,SPTSSA,PDIA6,ALDH9A1,CSTF1,NOL12,AMPD2,ERMP1,PSPC1,DNAJC9,GALK2,UBE4B,MTX1,PRMT2,PSMB9,HAGH,ZDHHC3,SRSF1,TMEM184C,TPD52L2,EPRS,NUCB1,NIP7,TOMM6,NEIL3,TYW5,HMGB2,SRSF3,PLOD3,PPP5C,CHPT1,HDAC2 |
| 1.333e-07 | -15.83 | mRNA catabolic process | biological process | GO:0006402 | 217 | 63 | 17256 | 2622 |
RPS15,RPS2,RPLP2,GSPT2,RBM8A,RPL15,THRAP3,CNOT11,PARN,METTL3,PAIP1,PRPF18,TUT4,CNOT3,EDC3,RPL23A,RPL11,CSDE1,EXOSC7,RPL17,EIF4A3,METTL14,PELO,EXOSC1,DCP1A,RPL19,UPF2,CNOT6L,PABPC1,SAMD4B,RPL29,RPL35,EXOSC6,POLR2G,RPL6,POLR2D,RNPS1,RPL8,RPL38,RPS10,RPS24,EXOSC9,RPL27A,PATL1,RPS9,RPSA,HSPA1B,RPL36,CNOT9,RPL37,PPP2CA,UPF1,RPL32,RPS27A,LSM6,RPS14,NT5C3B,RPLP1,KHSRP,DDX5,CNOT6,SMG9,RPS26 |
| 1.340e-07 | -15.83 | NDUFB11 (NADH:ubiquinone oxidoreductase subunit B11) | protein interactions | 54539 | 53 | 25 | 17029 | 2761 |
NDUFV2,NDUFS1,NDUFB6,TMEM126B,CYSTM1,LAMTOR3,NDUFA4,ABCB10,NDUFA7,NDUFB1,NDUFS7,NDUFS4,SDHB,NDUFV1,SURF4,NDUFA2,NDUFB4,NDUFA11,NDUFB9,NDUFS8,NDUFS5,APOOL,DNAJC30,NDUFA3,TMX1 |
| 1.346e-07 | -15.82 | GO_MICROTUBULE_CYTOSKELETON_ORGANIZATION_INVOLVED_IN_MITOSIS | MSigDB lists | GO_MICROTUBULE_CYTOSKELETON_ORGANIZATION_INVOLVED_IN_MITOSIS | 39 | 20 | 17377 | 2626 |
ZNF207,KIF3B,RHOA,BIRC3,XIAP,TPX2,TUBGCP5,MYBL2,KIF23,RACGAP1,AURKB,KIF11,RAB11A,TUBGCP2,BIRC2,KIF2A,KIFC1,GOLGA2,BIRC5,CHEK2 |
| 1.346e-07 | -15.82 | GO_MITOTIC_SPINDLE_ASSEMBLY | MSigDB lists | GO_MITOTIC_SPINDLE_ASSEMBLY | 39 | 20 | 17377 | 2626 |
ZNF207,KIF3B,RHOA,BIRC3,XIAP,TPX2,TUBGCP5,MYBL2,KIF23,RACGAP1,AURKB,KIF11,RAB11A,TUBGCP2,BIRC2,KIF2A,KIFC1,GOLGA2,BIRC5,CHEK2 |
| 1.347e-07 | -15.82 | regulation of proteasomal ubiquitin-dependent protein catabolic process | biological process | GO:0032434 | 123 | 42 | 17256 | 2622 |
USP7,SUMO2,UBXN1,NKD2,SIRT2,UBQLN2,CSNK1A1,PSEN1,BCAP31,ANKIB1,PARK7,FBXO22,DDRGK1,USP5,RAD23A,RPL11,MDM2,DDA1,RAD23B,RNF19A,SENP1,SOCS5,RYBP,PLK1,PLK3,UBQLN4,LONRF3,RBX1,PBK,GBA,HSPA1B,GNA12,HSPBP1,KEAP1,SOCS4,OGT,DVL1,CLU,RNF14,CSNK1D,RNF114,SVIP |
| 1.368e-07 | -15.80 | GARY_CD5_TARGETS_UP | MSigDB lists | GARY_CD5_TARGETS_UP | 447 | 109 | 17377 | 2626 |
WASF2,ZNF207,AGRN,RAB11B,NF1,PRKCSH,AGPAT1,HCFC1R1,MAP1LC3B,GNB2,SLC25A37,KIAA1147,CALM2,NUP210,CDC42,THAP4,MTA1,SUCLG2,TTC3,MAST2,METTL9,AHCYL1,GM2A,CPNE1,SLC39A9,MND1,MAPRE2,PPP1R18,PBXIP1,BTG2,GNG7,TAOK1,LRBA,WBP2,WIPF1,AURKB,OGFR,STX16,TAZ,SOCS7,C19orf54,TRIM4,MRPL2,MID1IP1,WAS,NAGLU,STAT1,SH3GLB2,ATXN2L,CAB39,DHTKD1,SCARB1,GLCCI1,AAAS,PDCD4,PTOV1,NAT14,MIF4GD,DHPS,HLA-E,SESTD1,TOR3A,CDT1,TRIO,TRAK1,STRN4,TKT,FLOT1,LETMD1,MEF2A,IL21R,SRRT,CNOT3,RGS1,GNS,HERC3,GART,SLC1A4,RIMS3,PHF14,LTN1,BCL2,PIK3IP1,CNOT6L,GNAI2,LRSAM1,SLC25A1,KDELR1,FDFT1,TGFB1,PPP1R9B,IFRD1,TNFAIP3,PRRC2A,PACS1,ARID1A,STYXL1,SF3A2,MAP2K2,TARS,DAPK3,KPNA1,CTBS,ACLY,LPCAT4,CEBPG,MEGF9,GPI,TMEM159 |
| 1.372e-07 | -15.80 | GO_MICROTUBULE_CYTOSKELETON_ORGANIZATION | MSigDB lists | GO_MICROTUBULE_CYTOSKELETON_ORGANIZATION | 315 | 83 | 17377 | 2626 |
ZNF207,FGFR1OP,ATXN3,XIAP,TPX2,MYH9,KIF2C,CNTROB,CCNB1,STMN1,BIRC2,KIFC1,DST,NEK6,DNAAF2,KIF14,XRCC2,CEP63,RNF19A,TACC3,PLK3,PLK1,PSRC1,BIRC3,FOPNL,TUBGCP5,EZR,NUSAP1,AURKB,BRCA1,BICD2,KIF2A,KIF18B,CHD3,AXIN1,MAP4,CHEK2,DVL1,VPS4A,SASS6,DYNC1LI2,CSNK1D,TUBB,KIF3B,PPP1R12A,EYA1,DCTN2,CIB1,KIF23,RACGAP1,HAUS4,RAB11A,TUBGCP2,HAUS2,SPAG5,LMNA,FBXO5,STARD9,SMC3,CCP110,CENPJ,PRC1,ARHGEF2,GCC2,RHOA,TACC1,ASPM,NEK7,MYBL2,MAP7D1,WDR81,KIF11,HAUS8,PCM1,KIF18A,GOLGA2,BIRC5,SLC16A1,PKD2,NDE1,WDR62,CDK2,ESPL1 |
| 1.372e-07 | -15.80 | GO_CELLULAR_PROTEIN_COMPLEX_ASSEMBLY | MSigDB lists | GO_CELLULAR_PROTEIN_COMPLEX_ASSEMBLY | 315 | 83 | 17377 | 2626 |
ZNF207,NDUFA5,COX15,CHMP2A,TOMM20,CORO7,NDUFB6,NDUFAF2,UQCR10,RAC1,POMP,ATPAF1,MIS12,AHCTF1,DNAAF2,NUP107,TNPO2,AP2B1,NDUFB9,NUP153,CCT2,NCK1,TUBGCP5,ATP6V0A1,PSMG1,NDUFA7,NDUFB1,ANLN,RAB1A,FOXRED1,TAZ,HSPA4,SMAD2,MID1IP1,WAS,CHMP4A,TMED10,PSMD8,AXIN1,NDUFA11,CLU,SMAD1,AP2S1,SMAD4,CSNK1D,SLC25A33,TMEM33,NDUFV2,NDUFS1,CENPF,PSMD9,TUBGCP2,NDUFS7,NUP205,FBXO5,NDUFS4,FKBP1A,NDUFV1,NDUFA2,NDUFB4,CENPJ,MBD2,ATP6V0A2,NDUFS8,TTC17,NDUFA3,TMED2,TGFB1,TIMMDC1,TMEM126B,ADRB2,EIF4H,PICALM,BBS12,CAND1,GOLGA2,SNAP23,SNAP29,NDUFS5,CENPT,NDE1,UBE2C,IPO4 |
| 1.373e-07 | -15.80 | respiratory chain | cellular component | GO:0070469 | 88 | 33 | 18223 | 2701 |
COX5B,NDUFA5,COX15,NDUFV2,NDUFS1,NDUFB6,UQCR10,NDUFA4,COX4I1,CYCS,SDHA,PARK7,NDUFS7,NDUFS4,NDUFV1,NDUFA2,NDUFB4,NDUFS8,NDUFB9,CYC1,NDUFA3,DMAC2,NDUFA7,NDUFB1,FOXRED1,SDHB,NDUFA11,COX7A2L,COX8A,COX5A,UQCRH,NDUFS5,HIGD2A |
| 1.373e-07 | -15.80 | Sm-like protein family complex | cellular component | GO:0120114 | 80 | 31 | 18223 | 2701 |
SART1,SNRNP200,SNRPB,SF3B1,SF3B6,LSM8,DDX20,PRPF3,SNRPD3,PRPF39,TXNL4A,LUC7L,SF3A2,SNRPA,CLNS1A,PRPF18,SF3B2,DDX23,GEMIN5,LSM6,LUC7L3,EFTUD2,GEMIN6,PRPF4,SNRPG,GEMIN4,WDR62,SNRNP70,STRAP,LUC7L2,GEMIN7 |
| 1.376e-07 | -15.80 | macromolecule methylation | biological process | GO:0043414 | 236 | 67 | 17256 | 2622 |
ASH1L,DNMT3A,NOP2,KMT2E,SUZ12,CXXC1,NSD3,SNRPD3,TET3,KMT5C,THADA,METTL14,DNMT1,FTSJ3,ARID4A,CARM1,MRM2,METTL1,BAZ2A,SNRPB,BTG2,EHMT1,NSUN2,METTL2A,WDR82,ICMT,KDM1B,KMT2C,TRIM28,DOT1L,WDR4,CAMKMT,OGT,FTSJ1,BEND3,RPS2,MECP2,TRMT6,RAB6A,EZH1,WDR5,RLF,METTL3,GTPBP3,IRF4,SUV39H2,CMTR2,KMT5A,PRDM4,ZNF335,CTR9,FBL,NSUN4,MRM3,HEMK1,MTA2,ARMT1,RTF1,METTL22,PRMT2,MEN1,KDM3A,GNAS,SETD3,PRMT7,KMT2B,TRMT10B |
| 1.392e-07 | -15.79 | RPL9 (ribosomal protein L9) | protein interactions | 6133 | 170 | 55 | 17029 | 2761 |
RPS15,RPS2,CYLD,RPLP2,DHPS,DHX9,RPL15,CUL1,KIF2C,RPL11,RPL23A,RPA2,RPL17,RBM34,AHSA1,EXOSC1,RPL19,TARDBP,POLR1B,FBL,FTSJ3,SLC25A1,CDC5L,STAU1,RPL29,RPL35,RPS10,RPL6,CUL3,ILF3,RPL8,RPL38,TUFM,MRPS10,RPS24,MRPL16,BRCA1,MCM2,RPL27A,SLC25A5,RHOT2,RPS9,RPSA,RPA1,CAND1,RPL36,NAP1L1,RPL32,RPS27A,RPS14,RPLP1,FUS,SRSF3,RRS1,RPS26 |
| 1.422e-07 | -15.77 | mitotic spindle assembly | biological process | GO:0090307 | 49 | 23 | 17256 | 2622 |
BCCIP,ZNF207,KIF3B,MZT1,RHOA,BIRC3,XIAP,TUBGCP5,MYBL2,TPX2,KIF23,RACGAP1,AURKB,KIF11,RAB11A,BIRC2,TUBGCP2,KIF2A,KIFC1,GOLGA2,BIRC5,ABRAXAS2,CHEK2 |
| 1.424e-07 | -15.76 | protein targeting | biological process | GO:0006605 | 294 | 79 | 17256 | 2622 |
TOMM20,MTX3,RPLP2,VTI1A,SSR1,RPL23A,RPL11,TIMM23,ATG3,TIMM50,CDC37,SRP72,LARS,RPL29,SEC61B,RPL35,RAB7A,RPL38,ERBIN,ICMT,AP4E1,RPS9,RPSA,RPL37,PEX5,CHMP4A,TIMM13,HSPA4,SEC61A1,RPS27A,TIMM29,RPS14,TIMM17A,RPLP1,CHMP4B,CLU,VPS4A,SMURF1,PITRM1,RPS26,LONP2,PARD3,RPS15,RPS2,SEC61G,NUP54,TRAK1,RPL15,TIMM21,ATG4A,RPL17,KIF13B,FBXO7,ARL6IP1,RPL19,MTX2,NAGPA,ZDHHC18,GCC2,TIMM8B,RPL6,RPS10,RPL8,RPS24,SSR2,MTX1,RAB3IP,TOMM40,RPL27A,ZDHHC3,RPL36,MFN2,SCARB2,HGS,RPL32,GOLGA7,EXOC4,ZDHHC7,SPCS3 |
| 1.424e-07 | -15.76 | NIFK (nucleolar protein interacting with the FHA domain of MKI67) | protein interactions | 84365 | 149 | 50 | 17029 | 2761 |
NOP9,NIFK,RPS2,ZCCHC9,NOP2,RRP15,YTHDC2,MRPS26,RPL15,ARGLU1,NKRF,EBNA1BP2,BRIX1,TTF1,RPL11,KRR1,UTP18,RBM34,NOC2L,RPF2,DDX31,RPL19,MRPL48,FBL,ZNF770,FTSJ3,NOL12,SRP72,DDX24,GTPBP4,MKI67,CUL3,ZNF574,SREK1,RPS24,TOPORS,BMS1,BUD13,CAND1,NSA2,UPF1,DGCR8,ZNF689,TBL3,BBX,RRS1,ZBTB11,ZC3HAV1,IFI16,PRPF4B |
| 1.427e-07 | -15.76 | GO_CYTOSKELETAL_PART | MSigDB lists | GO_CYTOSKELETAL_PART | 1317 | 266 | 17377 | 2626 |
FGFR1OP,PDCD6IP,ADD1,XIAP,CNTROB,CCNB1,KIFC1,CALM2,ANKRD26,NEK6,DNM2,SUCLG2,FNIP2,CDC25B,KCNAB2,PLK3,AATF,NSUN2,KIF15,TOPORS,AURKB,DIDO1,CCNF,SLC25A5,KRIT1,MID1IP1,RAD18,KIF18B,AXIN1,MAP4,MYO18A,TRAF5,AAAS,ANXA11,HSPH1,MAPRE1,DHX9,KIF23,HAUS4,PSEN1,HAUS2,MYL6B,LMNA,SPAG5,CEP104,SMC3,ARPC5,FBXL7,GNAI2,NUP85,ELL2,WDR1,MAP7D1,CAPZA2,MAP2K2,CCT8,FNTA,GOLGA2,FAM83D,MDH1,NDE1,CDK2,ALS2,ZNF207,RAB11B,POC1A,ACTR3,RAC1,TPX2,OLA1,MYH9,NIT2,BCL2L1,PRKACA,STMN1,APP,CLUAP1,MTA1,NUP107,SEPT11,CEP63,RNF19A,RPRD1B,DCTN1,CCT2,PSRC1,MAPRE2,NARF,CUL3,NUSAP1,EML4,SERP1,KIF2A,PPP2CA,CDC16,CCDC14,TRIM32,GEN1,XRCC4,LRP8,DYNC1LI2,TUBB,CSNK1D,MZT1,PKP4,FLOT1,IFT27,RAB11A,MAD2L2,NEIL2,JAKMIP1,CAPN2,CLIC4,CENPJ,AXIN2,PRC1,GTSE1,CNN2,IFT46,NCOA2,NUDC,PDLIM2,SPTAN1,STAU1,KAT2A,TACC1,NEK7,PARP4,JTB,RAB3IP,KIF11,MACF1,SPPL2B,MARK2,MYO1F,CBX3,YIF1A,KEAP1,KIF18A,TTLL4,LRPPRC,SSNA1,WDR62,IGBP1,ESPL1,BYSL,SKA3,NPHP4,KIF2C,SIRT2,MAPK14,MAP1LC3B,BIRC2,DST,RAB8A,PCNA,CDC42,SYNM,DPYSL2,XRCC2,RCSD1,KIF22,RP2,MTPN,RPP25,PLK1,SEPT9,PBXIP1,FOPNL,CKAP2L,EZR,CDC6,BRCA1,ANLN,DPYSL3,EPB41,HSPB11,SEPT1,CHD3,PQBP1,DVL1,VPS4A,ROCK1,SASS6,MYL12B,TMUB1,PPP1R12A,CENPF,CIB1,KLC1,RACGAP1,DTL,RB1,CCP110,KIF13B,CAPZA1,KIFAP3,KNTC1,MCPH1,ATP6V0D1,CAMSAP1,PSMA1,SEPT7,ARPC1A,DAPK3,MASTL,HAUS8,TSC1,PCM1,CDC27,ODF2,SLC16A1,NUP62,MYO9A,CCNB2,MZT2B,CYLD,DYNLL1,SLC2A1,MEAF6,WDR44,KIF14,CORO1A,DNAL4,POC5,PRPF19,BIRC3,TUBGCP5,WIPF1,CEP55,GAS2,REEP4,MAPK1,RAD51D,KIF3B,CTDP1,KLHL21,DCTN2,SCYL1,CDCA8,PAWR,MYO9B,NCAPG,CSNK1A1,TUBGCP2,SAC3D1,FBXO5,FERMT3,KIF5B,STARD9,MZT2A,SLC1A4,ARHGEF2,MYO5A,ASPM,RANGAP1,WDR81,HSPA1B,NEK1,ATP6V1D,FAM110A,BIRC5,SNAP29,USP20,PKD2,TERF1 |
| 1.430e-07 | -15.76 | translational elongation | biological process | GO:0006414 | 119 | 41 | 17256 | 2622 |
MRPL9,RPLP2,MRPL42,MRPS2,MRPS15,MRPL39,MRPS26,SECISBP2,EFL1,MRPL19,GFM2,EEF2K,MRPL50,EFTUD2,MRPS27,MRPL34,MRPL54,LTN1,MRPL40,MRPL48,MRPL21,MRPL11,MRPL32,MRPL57,EEF1D,EIF5A,MRPL43,MRPL12,TUFM,MRPS10,MRPL16,MRPS14,MRPL2,DAP3,MRPL55,CHCHD1,MRPL27,RPLP1,MRPL13,MRPL3,ZNF598 |
| 1.430e-07 | -15.76 | RPL23A (ribosomal protein L23a) | protein interactions | 6147 | 183 | 58 | 17029 | 2761 |
RPS15,RPS2,CYLD,NOP2,RPLP2,SF3B1,TCF3,EIF3D,RPL15,CUL1,SND1,BLM,RPL11,LYAR,PA2G4,DDX56,MDM2,IARS,RPL17,YBX1,RPL19,TARDBP,HNRNPM,RPL29,RPL35,RPS10,RPL6,TUFM,CUL3,ILF3,RPL8,RPL38,MRPS10,RPS24,MRPL16,BRCA1,MCM2,RPL27A,SLC25A5,KIF11,RPS9,RPSA,CAND1,RPL36,EPRS,C1orf131,SYNCRIP,RPL32,RPS27A,RPS14,QARS,RPLP1,H2AFX,RRS1,FAU,CDK2,CD81,RPS26 |
| 1.430e-07 | -15.76 | RPS16 (ribosomal protein S16) | protein interactions | 6217 | 183 | 58 | 17029 | 2761 |
RPS15,RPS2,CYLD,RPLP2,RBM8A,RPL15,CUL1,SND1,APP,RPL11,RPL23A,DDX56,RPL17,HUWE1,AHSA1,ZNF746,EXOSC1,RPL19,TARDBP,ATP6V0D1,PABPC1,HNRNPM,CDC5L,EIF3L,RPL29,RPL35,MLEC,RPS10,RPL6,TUFM,RPL38,CUL3,ILF3,RPL8,RPS24,AURKB,BRCA1,EIF2A,MCM2,RPL27A,RPS9,RPSA,RPL36,CAND1,RPL32,RPS27A,RPS14,WDR4,RPLP1,H2AFX,DDX5,RRS1,FAU,CDK2,CD81,SMURF1,RPS26,TERF1 |
| 1.444e-07 | -15.75 | GSE41867_DAY15_EFFECTOR_VS_DAY30_EXHAUSTED_CD8_TCELL_LCMV_CLONE13_DN | MSigDB lists | GSE41867_DAY15_EFFECTOR_VS_DAY30_EXHAUSTED_CD8_TCELL_LCMV_CLONE13_DN | 186 | 56 | 17377 | 2626 |
RMND5A,PWWP2A,CDS2,NDUFS1,EYA1,TRMT6,GPR89A,TMEM97,JMJD6,TOP2B,ORC1,RUFY1,FOXO3,UBXN2A,NUS1,EIF2S2,NOL11,RNFT1,THAP4,IL6ST,DNAAF2,ATP13A3,MRPL54,RPN2,TARDBP,MCMBP,STRAP,TMED2,CDC5L,PPIF,ADAM17,MAPRE2,MKLN1,GALC,GABPA,TMEM126B,OXR1,DCUN1D5,GFER,MAK16,EML4,LSG1,TWISTNB,NMT2,RAB18,TRAM2,PPP2R5A,STT3A,SNAP23,PTER,MAPK6,TFDP1,PIAS2,OGT,FBXL3,GPR89B |
| 1.444e-07 | -15.75 | GSE24671_BAKIMULC_VS_SENDAI_VIRUS_INFECTED_MOUSE_SPLENOCYTES_UP | MSigDB lists | GSE24671_BAKIMULC_VS_SENDAI_VIRUS_INFECTED_MOUSE_SPLENOCYTES_UP | 186 | 56 | 17377 | 2626 |
COMMD10,PTMS,DEPDC1,SEC61G,CHTF18,PTTG1,PTP4A3,NENF,GLRX3,REEP5,MRPL19,TUBGCP2,TFRC,SPAG5,KIFC1,DTL,CDKN2C,EIF2S2,CCP110,MCM5,INTS12,YBX1,CENPM,PRADC1,MTX2,MRPL32,SMC4,GINS1,SRP72,CCT2,PSRC1,RAD51AP1,VDAC2,CCDC34,CKAP2L,CDC6,CDCA2,PKMYT1,MPG,KIF11,RHBDF2,HSPA1B,OPTN,NAP1L1,HSPB11,KIF18A,HINT1,QARS,NRM,TICAM1,CENPT,GAS2,EHD4,WDR91,WDR62,TMEM14A |
| 1.444e-07 | -15.75 | GSE17721_0.5H_VS_8H_LPS_BMDC_UP | MSigDB lists | GSE17721_0.5H_VS_8H_LPS_BMDC_UP | 186 | 56 | 17377 | 2626 |
PPIB,IER2,GCLM,C19orf53,MRPL42,MRPS15,GNPDA1,MRPL39,MANBA,DAP,HABP4,PIP4K2A,PARK7,XPR1,DDX56,ATG3,MEA1,SOCS6,DAPK1,MRPL34,CTR9,ATP6V0A2,TTC4,CORO1A,CLTB,PHKG2,IMPA2,METTL1,TDP1,ERMP1,RBX1,IDH3A,NQO2,RPL6,POLR2D,RPL38,SEPT8,HEBP2,HTATIP2,CDC6,PACS1,GALK2,ADRB2,ANLN,TXNL4A,NEU1,MAPK3,HHEX,TPD52L2,GALNT2,MRPL55,RWDD4,ACAT1,CCNB2,HIGD2A,FAF1 |
| 1.460e-07 | -15.74 | Golgi apparatus part | cellular component | GO:0044431 | 936 | 196 | 18223 | 2701 |
TMED7,RAB14,AGRN,COPA,ADAM10,TGOLN2,CDIPT,SEC16A,BECN1,SYNRG,RIC1,RAB8A,ASAP2,CDC42,RAB35,IMPAD1,PHTF1,AP1M1,DNM2,AP2B1,TFG,SLC35C2,MGAT5,RHBDD2,PLK3,PGAP2,USO1,RHOBTB3,TMEM115,NRAS,ATG9A,LAP3,APH1A,PITPNB,GALNT7,MCFD2,STX16,SLC50A1,RAB2B,RHEB,OPTN,MAN2A2,TMED10,MYO18A,ST3GAL2,ROCK1,GALNT10,CLN3,CHPT1,CHPF2,RTN3,NAA60,B4GALT2,SVIP,SCOC,AGTRAP,GORASP1,HLA-E,SDC2,PCSK7,B4GALT1,SLC35B1,RAB6A,TMED3,NOTCH2,B4GALT4,PSEN1,TMEM165,QSOX2,COPG2,COPB2,CD59,C1GALT1,RNF121,PPIL2,TPST1,PIKFYVE,LPCAT1,PPP6R1,TMED2,PREB,KDELR1,NAGPA,CYTH1,GCC2,TRAPPC9,MAN1B1,MFNG,USF3,GORASP2,GOSR1,ZDHHC3,PI4K2A,SEC31A,SCARB2,GOLGA4,GALNT2,GOLGA2,NSF,ARAP1,ZDHHC7,VCPIP1,SAMD8,SMPD4,PPP6R3,ECPAS,CORO7,SYS1,GNPNAT1,SLC2A1,COPE,RAC1,GPR89A,VTI1A,SLC39A13,RXYLT1,SLC35B2,AP1B1,APP,EXT2,BCAP31,ANKRD28,UBXN2A,RAB21,SAR1A,PPP6C,NSFL1C,LMAN1,CLTB,GCC1,EBAG9,CHP1,MOSPD1,CLCN3,GOPC,CUL3,PKMYT1,RAB1A,AP4E1,PEF1,ERC1,SURF4,SCAP,GOLGA8A,CANT1,AP1S1,ATF6,B4GALT3,CHID1,CSNK1D,GOLIM4,GOLPH3L,TMBIM4,B4GALT5,SCYL1,VPS45,ARFIP2,AGPAT3,ARF1,GGA2,RAB11A,HLA-A,MAN1A1,PDCD10,KLHL20,SEC24C,FUT8,SLC35B4,ZDHHC13,YIF1B,ST8SIA2,SLC35A1,LYPLA2,TGFB1,B3GALT6,MOB4,ATP2C1,RFFL,COG1,PNPLA8,SPPL2B,SH3GLB1,YIF1A,HLA-B,NUCB1,SEC23IP,PDCD6,GOLGA7,WNT5B,SNAP29,STX18,GLG1,PLOD3,HRAS,GPR89B,SNAPIN |
| 1.462e-07 | -15.74 | TARTE_PLASMA_CELL_VS_B_LYMPHOCYTE_UP | MSigDB lists | TARTE_PLASMA_CELL_VS_B_LYMPHOCYTE_UP | 75 | 30 | 17377 | 2626 |
PPIB,SEC61B,ELL2,SELPLG,SRGN,HEXB,SLC35B1,FKBP2,ICAM2,HAGH,ARF4,NEU1,SSR1,MAN1A1,YIF1A,ALG3,IRF4,TRAM2,PLD3,RPN1,DDOST,STT3A,TMED10,FUT8,SEL1L,RPN2,PDXK,CITED2,PDIA6,KDELR1 |
| 1.484e-07 | -15.72 | GSE17721_LPS_VS_GARDIQUIMOD_4H_BMDC_DN | MSigDB lists | GSE17721_LPS_VS_GARDIQUIMOD_4H_BMDC_DN | 177 | 54 | 17377 | 2626 |
RHOG,MMACHC,TMED7,RPS2,TOMM20,MAPRE1,ZCCHC8,IVNS1ABP,SRSF6,MUM1,SCYL1,SLC2A1,SNX15,CERK,B4GALT1,MEF2A,ATG2B,MYO9B,C14orf119,VASP,C18orf32,IARS,INPP5A,PPP4R1,MEA1,TTC3,MAP3K14,TMEM8A,EIF5,HDHD2,PACS2,POLR2I,FAM49B,SUGP2,LDHA,USP10,MEF2D,SF3A2,NEU1,SUPT16H,YIF1A,TSC1,FNTA,PDCD6,TTC13,CDCA5,WDR4,TBPL1,PPP3R1,LONP2,BYSL,ZNF146,PDF,FUBP1 |
| 1.484e-07 | -15.72 | GSE2706_UNSTIM_VS_8H_LPS_DC_UP | MSigDB lists | GSE2706_UNSTIM_VS_8H_LPS_DC_UP | 177 | 54 | 17377 | 2626 |
KCTD7,KIAA0100,GNPDA1,KLHL21,UFC1,MRPS26,CERK,HAUS4,EIF2AK4,MAPK14,JMY,GSTK1,INPP5A,SNX18,POP7,YIF1B,CYB5R1,SLC26A2,GPD1L,TMEM9,IMPA2,RNF169,ALDH9A1,NTPCR,ABHD2,FAM118B,PRKDC,MRPL43,UBE4B,ICMT,NDRG3,TMEM201,NMT2,RPA1,STOML2,MYO1F,YIF1A,C19orf54,MAN2A2,PON2,HHEX,TRAM2,BOLA3,PCM1,ITPRIPL1,TTC13,DUSP3,VPS26B,WNT5B,FN3KRP,DTD1,TRIM32,LTA4H,CHID1 |
| 1.484e-07 | -15.72 | GSE46606_DAY1_VS_DAY3_CD40L_IL2_IL5_STIMULATED_BCELL_DN | MSigDB lists | GSE46606_DAY1_VS_DAY3_CD40L_IL2_IL5_STIMULATED_BCELL_DN | 177 | 54 | 17377 | 2626 |
OTUD5,NPHP4,C19orf53,TRERF1,NOP2,PHRF1,KIAA0232,ARID5A,SLC39A13,JMJD6,SAFB2,RMI1,MAD2L2,TFRC,TNFAIP8,RALB,EI24,FBXW2,ATP6V0A2,TTC4,MVP,STAT3,RNF5,NOL12,TGFB1,METTL1,AGGF1,ZNF559,BIRC3,LONRF3,CDC123,METTL5,PFKFB3,MCL1,PITPNB,EDF1,RAB22A,BOLA3,TIMM13,MTHFD2,PALB2,TXNDC16,CSK,TYW5,STAT1,WDR7,NLRC5,CAB39,FKBP5,CLU,RRS1,NUDT11,IFI16,GPATCH4 |
| 1.495e-07 | -15.72 | VPS35 (VPS35, retromer complex component) | protein interactions | 55737 | 78 | 32 | 17029 | 2761 |
UNK,SNX2,IVNS1ABP,RAB7A,OXR1,TRMT6,UBE4B,BRCA1,USP48,WDR5,TMEM165,TOLLIP,VPS25,APP,SAC3D1,CYHR1,IRF4,HGS,UPF1,VPS26B,CORO1C,USP32,H2AFX,ANP32E,TTC4,PSAP,ATP6V1C1,H3F3A,CDK2,ARRB2,VPS29,NUDC |
| 1.495e-07 | -15.72 | RPRD1B (regulation of nuclear pre-mRNA domain containing 1B) | protein interactions | 58490 | 78 | 32 | 17029 | 2761 |
SRM,CTDP1,TP53RK,EWSR1,PPP1R12A,ACTR3,EFL1,ATP6V1B2,NPLOC4,RPA2,RB1,KLHL20,HUWE1,PPME1,TTLL12,STRAP,ASB6,TERF2,RPRD1A,POLR2I,POLR2L,POLR2G,POLR2D,RANGAP1,BRCA1,POLR2A,RPA1,PFDN5,POLR2J,DUS3L,OGT,FUBP1 |
| 1.499e-07 | -15.71 | RNA catabolic process | biological process | GO:0006401 | 246 | 69 | 17256 | 2622 |
RPLP2,RBM8A,SND1,PAIP1,PABPC4,EDC3,RPL23A,RPL11,CSDE1,EIF4A3,METTL14,EXOSC1,RNASEH2A,RPL29,RPL35,EXOSC6,POLR2G,POLR2D,RNPS1,RPL38,RPS9,RPSA,RPL37,PPP2CA,RPS27A,LSM6,RPS14,NT5C3B,RPLP1,SMG9,RPS26,RPS15,RPS2,GSPT2,RPL15,THRAP3,PARN,CNOT11,METTL3,CNOT3,TUT4,PRPF18,EXOSC7,RPL17,PPP1R8,PELO,DCP1A,UPF2,RPL19,CNOT6L,PABPC1,SAMD4B,RNASEH2C,TRIR,RPL8,RPS10,RPL6,RPS24,EXOSC9,RPL27A,PATL1,RPL36,HSPA1B,CNOT9,UPF1,RPL32,KHSRP,CNOT6,DDX5 |
| 1.503e-07 | -15.71 | GSE2770_IL12_AND_TGFB_ACT_VS_ACT_CD4_TCELL_2H_DN | MSigDB lists | GSE2770_IL12_AND_TGFB_ACT_VS_ACT_CD4_TCELL_2H_DN | 168 | 52 | 17377 | 2626 |
MIB2,MIF4GD,DNMT3A,DHPS,DAP,VAV2,BABAM1,TMX4,TKT,ABHD14B,SND1,NDUFS7,NDUFS4,CDK5,SNRNP25,MZT2A,MCM5,AKAP8,PRC1,TTC3,GPD1L,TMEM14C,TACC3,CAMK2G,TSHZ1,NXT1,MAPRE2,TRIM8,BAZ2A,PPT1,MAN1B1,EZR,ESYT1,MTX1,ASB13,TAZ,NDRG3,PSMB9,ARHGAP15,EPB41,AMZ2,ALDH3B1,WAS,CCDC6,ELMO1,TATDN2,QARS,EIF2D,LTA4H,ACSF2,FAF1,NUDT3 |
| 1.530e-07 | -15.69 | GNF2_ANP32B | MSigDB lists | GNF2_ANP32B | 36 | 19 | 17377 | 2626 |
HNRNPAB,SUZ12,SUMO2,DNAJC9,GAR1,SRSF1,HMGN2,CBX3,MCM5,DUT,SRI,TRA2B,HMGB2,NUP153,ANP32E,PTGES3,SRSF3,HTRA2,SMC4 |
| 1.534e-07 | -15.69 | CRY1 (cryptochrome circadian regulator 1) | protein interactions | 1407 | 141 | 48 | 17029 | 2761 |
USP7,IMMT,TXN,CUL1,SNRPD3,PCBP1,SDHA,SCYL2,PABPC4,IARS,HUWE1,EFTUD2,TIMELESS,CRY2,PABPC1,ALDH9A1,NASP,PRKDC,HNRNPF,ILF3,DNAJA1,PKM,SLC25A5,CCT8,TRIM28,MATR3,PRDX1,HSPA1B,PSMC4,XRCC5,EPRS,SYNCRIP,LTBP4,RPS27A,PSMD3,RPS14,ARNTL,ACLY,LRPPRC,YWHAZ,RUVBL2,ATP5F1A,FBXL3,USP11,YWHAH,PSMC1,TUBB,CSNK1D |
| 1.564e-07 | -15.67 | GSE24574_BCL6_HIGH_TFH_VS_NAIVE_CD4_TCELL_DN | MSigDB lists | GSE24574_BCL6_HIGH_TFH_VS_NAIVE_CD4_TCELL_DN | 191 | 57 | 17377 | 2626 |
RHOG,CHMP2A,IMMT,FEZ2,CDS2,HNRNPAB,IVNS1ABP,URB2,DYNLL1,SRGN,ADO,PLAGL2,EBNA1BP2,CYCS,ARF1,FKBP2,PSMD9,MRPL19,PNO1,CFLAR,PRNP,HOMER1,PSMD1,EIF4A3,UTP18,TXLNA,ZNF200,SRI,RPN2,SS18L1,RP2,SLC26A2,LPCAT1,ANKLE2,SP3,COPS8,ADAM17,MKLN1,WDR1,HNRNPF,EZR,EMP3,PLEC,SLC25A5,RAB22A,FADD,PRDX1,CAND1,MTHFD2,LTBP4,UAP1,PRDX3,HPS5,SNRPG,PGAM1,CD81,SSSCA1 |
| 1.568e-07 | -15.67 | TAKAO_RESPONSE_TO_UVB_RADIATION_UP | MSigDB lists | TAKAO_RESPONSE_TO_UVB_RADIATION_UP | 83 | 32 | 17377 | 2626 |
PPIB,COX5B,IER2,TXN,H2AFZ,DYNLL1,UBXN1,NDUFA4,COX4I1,HNRNPA2B1,DST,ATP6V0B,PSMA6,ARF5,SRI,EEF1D,CDC37,GPX4,BAK1,POLR2L,RPL27A,RPS9,PFDN5,NAP1L1,PRDX3,GPS2,DBI,COX8A,COX5A,PPP1R11,FUBP1,PTOV1 |
| 1.569e-07 | -15.67 | MODULE_124 | MSigDB lists | MODULE_124 | 95 | 35 | 17377 | 2626 |
THOC1,CHERP,POLR2K,PHB2,DCTN2,PTTG1,KIF23,KIF2C,CCNB1,RBM4,PABPC4,HNRNPA2B1,CCNA2,KIF22,RBM3,KNTC1,CDC25B,CORO1A,TCEA1,PLK1,POLR2I,HNRNPF,POLR2D,E2F3,TBRG4,SMC2,POLR2J,BIRC5,E2F1,KPNA2,PPP5C,TAF6,CCNB2,UBE2C,CDK2 |
| 1.569e-07 | -15.67 | MORF_PPP6C | MSigDB lists | MORF_PPP6C | 95 | 35 | 17377 | 2626 |
RAE1,COX4I1,UBE4A,CDIPT,PSMD9,RBM4,MBD4,SEC11A,UTP18,SIVA1,RAD23B,BUD31,PPP6C,EIF5,EEF1D,RBM42,POLR2G,DPM1,DNAJA1,CHMP2B,NDUFB1,STX16,PAF1,PDCD6,TMED10,DBI,COX5A,WIPI2,SNRPG,YY1,PITRM1,PSMC1,COIL,FUBP1,RNF114 |
| 1.573e-07 | -15.66 | V$E2F_Q6 | MSigDB lists | V$E2F_Q6 | 219 | 63 | 17377 | 2626 |
POLA2,H2AFZ,CLSPN,ZCCHC8,RAB11B,CDT1,TRMT6,RMI2,SMC6,CTCF,ASXL2,STMN1,FBXO5,TFAP4,PCNA,SMC3,INTS7,CD3EAP,PPP1R8,FIZ1,MSH2,TRA2B,NUP153,PCYT2,MRPL40,MCMBP,DNMT1,ARID4A,SP3,YTHDC1,ZNF524,NASP,APH1A,PRKDC,ILF3,E2F3,RRM2,DNAJC9,SREK1,CDC6,NFATC2IP,PBRM1,PKMYT1,MCM2,APPL1,POLR2A,CAND1,SRSF1,DDX17,HMGN2,ATAD2,HNRNPR,RBL1,DCK,ZNF367,LUC7L3,KBTBD7,E2F1,NUP62,WDR62,SASS6,GEN1,PRPF4B |
| 1.583e-07 | -15.66 | PA2G4 (proliferation-associated 2G4) | protein interactions | 5036 | 137 | 47 | 17029 | 2761 |
ZNF207,TMED7,RPLP2,PRKAA1,DHX9,RPL15,USP39,NANS,ATP5F1B,SND1,UBE2I,CPNE3,RPL11,RPL23A,EEF2K,HNRNPA2B1,RB1,MDM2,EIF2S2,DNAJC8,DDA1,UBA5,CS,ANXA5,YBX1,PPA1,PDPK1,MRPL12,RPL8,ATP6V0A1,BRCA1,EIF2A,MCM2,HSPA1B,EIF3K,HSPA4,SH3GLB2,ACTB,FUS,GPI,FAU,CDK2,NIPSNAP2,TERF1,MYL12B,CDKN2A,HDAC2 |
| 1.583e-07 | -15.66 | SF3B2 (splicing factor 3b subunit 2) | protein interactions | 10992 | 137 | 47 | 17029 | 2761 |
CYLD,THOC1,XAB2,SF3B1,SUZ12,COPE,RBM8A,CSNK2A1,THRAP3,SNRPD3,BLM,APP,RBM17,RPA2,VASP,EIF4A3,YBX1,TCEA1,PCBP2,TERF2,CDC5L,NOL12,SRSF11,STAU1,ZCCHC10,SNRNP200,RBM42,SF3B6,CUL3,PRPF3,BRCA1,SF3A2,RPSA,RPA1,CAND1,TIMM13,DHX16,RBMX,NEIL3,XRCC3,SNRPG,ZNF830,H3F3A,ARRB2,ECPAS,SMURF1,SMNDC1 |
| 1.587e-07 | -15.66 | GO_ELECTRON_TRANSPORT_CHAIN | MSigDB lists | GO_ELECTRON_TRANSPORT_CHAIN | 91 | 34 | 17377 | 2626 |
COX5B,NDUFA5,COX15,NDUFV2,NDUFS1,NDUFB6,NDUFAF2,UQCR10,MECP2,SLC25A12,NDUFA4,COX4I1,CYCS,SDHA,NDUFS7,NDUFS4,NDUFV1,NDUFA2,NDUFB4,NDUFB9,NDUFS8,CYC1,NDUFA3,NDUFA7,NDUFB1,POLG2,TAZ,SDHB,COX7A2L,NDUFA11,COX8A,COX5A,UQCRH,NDUFS5 |
| 1.613e-07 | -15.64 | Viral Messenger RNA Synthesis | REACTOME pathways | R-HSA-168325 | 43 | 22 | 10287 | 1696 |
NDC1,POLR2I,NUP188,POLR2G,POLR2L,POLR2K,RAE1,NUP54,POLR2D,NUP155,POLR2A,NUP205,GTF2F1,NUP210,POLR2J,NUP107,NUP62,NUP153,NUP58,NUP85,SEH1L,AAAS |
| 1.621e-07 | -15.63 | H2AFY2 (H2A histone family member Y2) | protein interactions | 55506 | 101 | 38 | 17029 | 2761 |
COX15,NOP2,URB2,SUZ12,RPL15,EBNA1BP2,BRIX1,RBM34,DNAAF2,MRPL34,H2AFY,RPF2,DDX31,ZNF770,ZNF189,CDKN2AIP,DDX24,TEX10,GTPBP4,RIOX2,RPL8,BMS1,DIDO1,MCM2,MAK16,DHX57,SUPT16H,NSA2,TRIM26,TONSL,BBX,PPM1G,RRS1,NKAPD1,PDCD11,IFI16,PRPF4B,SSRP1 |
| 1.626e-07 | -15.63 | PSMA5 (proteasome subunit alpha 5) | protein interactions | 5686 | 133 | 46 | 17029 | 2761 |
USP7,CAST,DCTN2,CUL1,IRF3,POMP,UBQLN2,PSEN1,APP,SRXN1,RAD23A,HNRNPA2B1,KIF5B,PSMD2,VASP,PSMD1,CLIC4,PSMA6,HUWE1,UCHL5,SEC24C,PLK1,EXOSC6,PSMA8,CUL3,PSMB7,PSMA1,PSMG1,KRAS,EXOSC9,BRCA1,SYVN1,PSMB9,PSMB3,CLNS1A,POLR2A,PSMC4,DDX23,CAND1,PSMD8,PSMD3,YWHAZ,CDK2,UBE2C,ECPAS,PSMC1 |
| 1.639e-07 | -15.62 | RPL26L1 (ribosomal protein L26 like 1) | protein interactions | 51121 | 158 | 52 | 17029 | 2761 |
RPS15,COX15,NIFK,RPS2,RPLP2,MECP2,DHX9,OLA1,DHX8,RPL15,CUL1,RBM4,RPL17,RBM34,ZNF746,RTCB,DDX31,ZC3H3,HNRNPM,NOL12,PPAN,STAU1,RPL35,ZNF512,RPL6,CUL3,RPL8,LSM8,PRPF3,MCM2,RPL27A,MAK16,RPS9,RPSA,CAND1,RPL36,NSA2,ZNF317,SYNCRIP,RPL32,DGCR8,QARS,RPS14,H2AFX,TRMT10B,ZRANB2,PRPF4,RPS26,CCDC59,ZC3HAV1,GPATCH4,BYSL |
| 1.656e-07 | -15.61 | GO_RIBOSOMAL_SUBUNIT | MSigDB lists | GO_RIBOSOMAL_SUBUNIT | 155 | 49 | 17377 | 2626 |
RPS15,RPS2,MRPL42,RPLP2,MRPS2,MRPS15,MRPS26,RPL15,MRPL19,RPL11,RPL23A,MCTS1,RPL17,RPL19,RBM3,MRPL21,MRPL11,RPL22L1,NSUN4,MRPL32,RPL29,RPL35,MRPL12,RPS10,MRPL43,RPL6,RPL8,RPL38,RPS24,MRPL16,RPL27A,MRPS14,RPS9,RPSA,RPL36,RPL37,MRPL2,DAP3,MRPL55,RPL32,RPS27A,RPS14,EIF2D,MRPL27,RPLP1,FAU,MRPL13,RPS26,MRPL3 |
| 1.656e-07 | -15.61 | CSR_LATE_UP.V1_UP | MSigDB lists | CSR_LATE_UP.V1_UP | 155 | 49 | 17377 | 2626 |
WSB2,SRM,MAPRE1,MZT1,CLSPN,FOXM1,CDCA8,NUF2,TCF19,C19orf48,POLR3K,HAUS2,FKBP1A,CDK5,LYAR,FARSA,PSMD2,PA2G4,UTP18,AHSA1,ARHGEF1,NOC2L,RPF2,KIF22,ASB6,PDCL3,PREB,NUDC,EIF5A,GTF3C6,PBK,DRAP1,MYBL2,RRM2,CCDC34,CDC6,EXOSC9,ANLN,SHCBP1,CBFB,PRIM1,RAD18,BIRC5,ZNF367,FAM83D,CHEK2,PPP5C,UBE2C,PDLIM5 |
| 1.656e-07 | -15.61 | GSE14000_TRANSLATED_RNA_VS_MRNA_16H_LPS_DC_DN | MSigDB lists | GSE14000_TRANSLATED_RNA_VS_MRNA_16H_LPS_DC_DN | 155 | 49 | 17377 | 2626 |
WSB2,RPS2,MZT1,LYRM4,RWDD1,RPLP2,ZFYVE21,GTF3A,SDF2L1,AP3S1,MIEN1,UBXN2A,C4orf3,PTEN,EI24,BRI3,JOSD1,CISD2,ARL5A,FGFR1OP2,TMED2,PDLIM2,CSNK1G2,ORAI2,HMGN1,NXT1,GUK1,HMGN4,APH1A,POLR2D,JTB,RPL38,RFFL,EMP3,ICMT,TXNL4A,SERP1,RPS9,RPL36,BOLA3,GOLGA7,DUSP3,TBPL1,TMEM219,SSNA1,ARRB2,NUDT3,SVIP,STARD3NL |
| 1.669e-07 | -15.61 | GO_MITOTIC_SPINDLE_ORGANIZATION | MSigDB lists | GO_MITOTIC_SPINDLE_ORGANIZATION | 64 | 27 | 17377 | 2626 |
ZNF207,KIF3B,RHOA,BIRC3,DCTN2,TUBGCP5,MYBL2,XIAP,TPX2,KIF23,RACGAP1,AURKB,CCNB1,KIF11,STMN1,RAB11A,BIRC2,TUBGCP2,KIFC1,KIF2A,SMC3,GOLGA2,BIRC5,MAP4,PRC1,CHEK2,WDR62 |
| 1.669e-07 | -15.61 | REACTOME_RESPIRATORY_ELECTRON_TRANSPORT | MSigDB lists | REACTOME_RESPIRATORY_ELECTRON_TRANSPORT | 64 | 27 | 17377 | 2626 |
NDUFA5,NDUFV2,COX5B,NDUFS1,NDUFB6,NDUFA4,COX4I1,CYCS,NDUFA7,NDUFB1,SDHA,NDUFS7,NDUFS4,SDHB,NDUFV1,NDUFA2,NDUFB4,NDUFA11,COX7A2L,COX8A,COX5A,NDUFB9,UQCRH,NDUFS8,CYC1,NDUFS5,NDUFA3 |
| 1.691e-07 | -15.59 | HIST2H2BE (histone cluster 2 H2B family member e) | protein interactions | 8349 | 125 | 44 | 17029 | 2761 |
USP7,MECP2,CHD1L,CUL1,SMARCA4,ARID1B,GNB2,CDC73,WWP2,MDM2,HUWE1,MCM5,H2AFY,BRD7,ANP32A,NAP1L4,ATF2,RNF169,SAP30,KAT2A,MAP4K4,USP42,CUL3,ILF3,AURKB,SMC2,PBRM1,USP22,MCM2,POLR2A,CAND1,KPNA1,PALB2,BRD2,HIPK2,STK38,H2AFX,FUS,H3F3A,CDK2,PARP10,SMURF1,HDAC2,SSRP1 |
| 1.691e-07 | -15.59 | VDAC2 (voltage dependent anion channel 2) | protein interactions | 7417 | 125 | 44 | 17029 | 2761 |
COX15,IMMT,PHB2,COX4I1,CYCS,ATP5F1B,SND1,APP,BCAP31,NDUFS4,RPN1,NDUFV1,ARF5,SEPT11,NDUFB9,CISD2,CYC1,TECR,ATF2,ATP6V0D1,MTX2,PHKG2,TMX1,ABCC1,GPX4,BAK1,PPT1,RAB7A,ADRB2,TOMM40,VDAC1,RAB1A,SLC25A5,RPSA,ZFR,SUGP1,ATP1A1,MAGT1,DDOST,MPV17,ACADM,ATP5F1A,CLN3,CDK2 |
| 1.700e-07 | -15.59 | large ribosomal subunit | cellular component | GO:0015934 | 118 | 40 | 18223 | 2701 |
MRPL9,RPLP2,MRPL42,MRPL39,RPL15,MRPL19,RPL23A,RPL11,MRPL50,RPL17,MRPL34,MRPL54,RPL19,RBM3,MRPL40,MRPL48,MRPL21,MRPL11,RPL22L1,NSUN4,MRPL32,RPL29,RPL35,MRPL43,RPL6,MRPL12,RPL8,RPL38,MRPL16,RPL27A,RPL36,GEMIN5,RPL37,MRPL2,RPL32,MRPL55,MRPL27,RPLP1,MRPL13,MRPL3 |
| 1.700e-07 | -15.59 | peptidyl-amino acid modification | biological process | GO:0018193 | 916 | 196 | 17256 | 2622 |
FGFR1OP,NUP188,KMT2E,CXXC1,DNAJC24,CSNK2A1,TAF6L,SIRT2,CCNB1,UBE2I,FKBP2,MAPK14,PARK7,ASPHD2,TET3,CDK5,ABL2,PCNA,NUP210,NEK6,NUP153,TAF5L,MAST2,SENP1,ARID4A,SEH1L,FGFR1OP2,CARM1,CDC37,PLK1,SP3,DPM1,AKT2,EHMT1,RIOX2,WDR82,TOPORS,USP22,AURKB,GALNT7,MCFD2,KRTCAP2,KMT2C,DOT1L,MKNK1,STT3A,OGT,CAB39,BAZ1B,VIPAS39,ST3GAL2,STK11,CHEK2,GALNT10,NAA60,AAAS,PPIB,CLSPN,DHPS,PRKAA1,TOP2B,EZH1,RAB6A,SUPT7L,RLF,NUP205,FKBP1A,RPN1,HDAC7,DAD1,PPIL2,TPST1,ZNF335,CTR9,BCL2,NUP85,PHKG2,CSNK1G3,MORC3,EIF5A,MAPKAPK3,LDB1,RTF1,SYVN1,NFATC2IP,VKORC1,METTL22,KDM3A,MAP2K2,ZDHHC3,DAPK3,NMT2,MASTL,MBIP,GALNT2,CSK,SETD3,CSNK1G1,TEX30,PIAS2,ZDHHC7,PRMT7,NUP62,RUVBL2,CFAP20,NAA20,CDK2,SGF29,NUP58,EGLN1,NDC1,ASH1L,SUZ12,SUMO2,NSD3,PRKACA,LYN,MEAF6,MDM2,KMT5C,BRPF3,MTA1,PIN1,NUP107,RPN2,LMAN1,ATF2,ABI1,PPIF,KAT7,PPIE,ELP4,KIAA1586,NUP155,MBD3,TRIM28,FKBP3,DDOST,JAK1,CLK3,HIPK2,STK38,NSMCE2,CAMKMT,FKBP5,BEND3,NCOA1,MAPK1,CBX4,CSNK1D,PDF,RAE1,MECP2,EYA1,SCYL1,NUP54,CDCA8,TMX3,JMJD6,WDR5,CSNK1A1,FGFR3,IRF4,GRK2,SUV39H2,CWC27,KMT5A,PPIG,PRDM4,FUT8,NAA50,KANSL2,OSTC,CAMK2G,PDPK1,ZDHHC18,CSNK1G2,KAT2A,PRKDC,RANGAP1,PPWD1,PRMT2,MEN1,MARK2,MAPK3,NEK1,MAGT1,GOLGA7,BIRC5,TTLL4,PRDX3,KMT2B,TAF12,PLOD3,HIPK3,GCSH |
| 1.718e-07 | -15.58 | CDC14B (cell division cycle 14B) | protein interactions | 8555 | 117 | 42 | 17029 | 2761 |
NIFK,MRPS2,MRPS15,MRPS26,CDCA8,CSNK2A1,NSD3,SIRT2,MRPL19,GTF2F1,KRI1,SUB1,MSH2,DDX31,KIF22,MRPL48,DNMT1,FTSJ3,MSH6,RNF169,AATF,ZNF512,TEX10,ELOA,CIRBP,MRPS10,NUSAP1,MRPL16,BMS1,CDCA2,AURKB,UTP3,MRPS14,ZNF174,USP36,RPL36,UBTF,BRD2,CCDC86,L3MBTL3,SNRNP70,MRPL13 |
| 1.727e-07 | -15.57 | Alzheimer's disease | KEGG pathways | hsa05010 | 165 | 53 | 7161 | 1149 |
NDUFA5,COX5B,NDUFV2,NDUFS1,NDUFB6,ADAM10,UQCR10,COX4I1,NDUFA4,CYCS,PPP3CB,ATP5F1B,ATP5PF,PSEN1,APH1B,APP,SDHA,NDUFS7,NDUFS4,CAPN2,CDK5,CALM2,NDUFV1,NDUFA2,ATP2A2,NDUFB4,NDUFS8,NDUFB9,CYC1,NDUFA3,PPP3CA,ADAM17,APH1A,NDUFA7,NDUFB1,FADD,MAPK3,FAS,SDHB,IDE,ATP5MC3,NDUFA11,COX7A2L,COX8A,PPP3R1,COX5A,UQCRH,ATF6,ATP5F1A,NDUFS5,MAPK1,RTN3,CAPN1 |
| 1.727e-07 | -15.57 | Alzheimer's disease | KEGG pathways | ko05010 | 165 | 53 | 7161 | 1149 |
NDUFA5,COX5B,NDUFV2,NDUFS1,NDUFB6,ADAM10,UQCR10,COX4I1,NDUFA4,CYCS,PPP3CB,ATP5F1B,ATP5PF,PSEN1,APH1B,APP,SDHA,NDUFS7,NDUFS4,CAPN2,CDK5,CALM2,NDUFV1,NDUFA2,ATP2A2,NDUFB4,NDUFS8,NDUFB9,CYC1,NDUFA3,PPP3CA,ADAM17,APH1A,NDUFA7,NDUFB1,FADD,MAPK3,FAS,SDHB,IDE,ATP5MC3,NDUFA11,COX7A2L,COX8A,PPP3R1,COX5A,UQCRH,ATF6,ATP5F1A,NDUFS5,MAPK1,RTN3,CAPN1 |
| 1.732e-07 | -15.57 | SNU13 (small nuclear ribonucleoprotein 13) | protein interactions | 4809 | 171 | 55 | 17029 | 2761 |
POLA2,SART1,NIFK,RPS2,SUZ12,TRMT6,RPL15,CNTROB,MAP1LC3B,PABPC4,RPL11,RPL23A,CDKN2C,DDX56,PCNA,ZNF326,CTPS1,NAA50,RPAP1,TRA2B,RPL19,CORO1A,FBL,PABPC1,HNRNPM,SRSF10,METTL1,SRSF11,GCC2,DDX24,WDR18,RPL6,RNPS1,RPS24,PRPF3,EIF2A,SRSF5,MCM2,TARS,RPSA,SUPT16H,CAND1,SYNCRIP,SURF4,HNRNPR,RPS14,CORO1C,IMPDH1,PRPF4,YY1,RRS1,CDK2,ECPAS,DDB1,IFI16 |
| 1.741e-07 | -15.56 | GNF2_MKI67 | MSigDB lists | GNF2_MKI67 | 27 | 16 | 17377 | 2626 |
PCNA,CCNA2,KIF18B,BIRC5,FOXM1,ASPM,CENPF,TPX2,MKI67,RRM1,RRM2,NUSAP1,NCAPG,KIF11,UBE2C,ESPL1 |
| 1.744e-07 | -15.56 | DCTN1 (dynactin subunit 1) | protein interactions | 1639 | 246 | 72 | 17029 | 2761 |
NDUFA5,SKA3,CYLD,LUZP1,DYNLL1,YTHDC2,MCCC1,EBNA1BP2,IRF3,KIF2C,CCNB1,SEC16A,MAP1LC3B,ABRACL,DST,RAB8A,SAR1A,RAB35,KIF14,DNM2,GPATCH1,CHTOP,MTPN,CCAR1,DCTN1,CDC37,PLK1,MAPRE2,CUL3,CKAP2L,AURKB,BRCA1,BICD2,EML4,EPB41,SUPT16H,KIF2A,STAT1,BTF3,DVL1,SMURF1,CEP170B,MAPRE1,MTERF1,DCTN2,NACA,STRN4,HAUS4,RAB6A,SPAG5,NPLOC4,GSTK1,PRC1,CAPZA1,BTF3L4,ARHGEF2,GTSE1,NAP1L4,CYFIP1,CAMSAP1,RFXANK,MAP7D1,EIF2A,CAPZA2,KIF11,MARK2,HAUS8,NAP1L1,UPF1,FAM83D,ECPAS,PGAM1 |
| 1.752e-07 | -15.56 | Nup98 (nucleoporin 98) | protein interactions | 269966 | 57 | 26 | 17029 | 2761 |
NDC1,NXT1,NUP188,RAE1,SUMO2,RPL6,NUP54,RANGAP1,NUP155,CDCA2,CHMP2B,UBE2I,NUP205,PON2,KPNA4,AHCTF1,NUP210,NUP107,NUP62,NUP153,SMPD4,GLE1,NUP85,NUP58,AAAS,SEH1L |
| 1.756e-07 | -15.55 | replication fork | cellular component | GO:0005657 | 69 | 28 | 18223 | 2701 |
POLA2,MCM10,RFC3,PRIM2,HELB,WDHD1,BLM,RFC2,GINS4,PRIM1,RPA1,RPA2,RAD51C,PCNA,RAD18,TONSL,XPA,XRCC2,H2AFX,TIMELESS,BAZ1B,XRCC3,TOP1MT,DNMT1,PURA,RAD51D,CDC5L,PRPF19 |
| 1.761e-07 | -15.55 | GSE16385_UNTREATED_VS_12H_ROSIGLITAZONE_IL4_TREATED_MACROPHAGE_UP | MSigDB lists | GSE16385_UNTREATED_VS_12H_ROSIGLITAZONE_IL4_TREATED_MACROPHAGE_UP | 187 | 56 | 17377 | 2626 |
BCL2L12,PIGM,ANKRD13D,GPR132,TP53RK,MAX,PNISR,NF1,TRIP10,ZCCHC8,HLA-E,TSC22D3,TRIM11,MRI1,LETMD1,CHIC2,CHKB,RAB11A,PABPC4,CNOT3,BCAT2,PPP1R3B,PA2G4,SHC1,ARF5,SSBP3,ARHGEF2,ANXA5,AP2B1,FGFR1OP2,CFL1,GPX4,KDM3B,EIF5A,CYTH1,ARHGAP17,RHOA,SEPT9,COQ10B,WDR1,MAN1B1,UTP15,UBE4B,SOX4,EPB41,UBTF,DDOST,SNAP29,ITGB1,SIAH2,SLC16A1,AKNA,SNRNP70,FBXL3,SLC25A39,SMNDC1 |
| 1.761e-07 | -15.55 | GSE19923_HEB_KO_VS_HEB_AND_E2A_KO_DP_THYMOCYTE_UP | MSigDB lists | GSE19923_HEB_KO_VS_HEB_AND_E2A_KO_DP_THYMOCYTE_UP | 187 | 56 | 17377 | 2626 |
CHMP2A,CUTA,TRIO,LAGE3,CDC42SE2,XPO7,PARN,FOXO3,SDHA,BIRC2,PIP4K2A,CPNE3,UBLCP1,USP5,CDKN2C,IRF4,NFATC3,PTEN,ZNF746,TIMELESS,CORO1A,TCEA1,LMAN1,RPRD1B,SAP30L,IMPA2,GPX4,SRPK2,ELOVL5,ASPM,ZMYND11,SUGP2,LDB1,DNAJC9,SLBP,NFATC2IP,CDC23,ICAM2,CCNF,FOXRED1,POLG2,SLC50A1,FADD,CYB5A,ECH1,EPB41,MAP3K4,TXNDC16,ACYP1,RBL1,ERGIC3,CDCA7L,SLAIN1,SSNA1,NCOA1,IGBP1 |
| 1.761e-07 | -15.55 | GSE5099_UNSTIM_VS_MCSF_TREATED_MONOCYTE_DAY3_DN | MSigDB lists | GSE5099_UNSTIM_VS_MCSF_TREATED_MONOCYTE_DAY3_DN | 187 | 56 | 17377 | 2626 |
MIB2,SART1,IER2,NCOR2,ANKRD13D,PKP4,KIAA0100,ANXA6,GGA1,TRIO,TKT,ENSA,CDIPT,WDR5,TWF2,PARN,MXD1,NPLOC4,FERMT3,EEF2K,TNS3,VASP,SIAH1,SH3BP1,CS,ARHGEF2,PLCL2,ZNF710,MTPN,CTDSP2,S100A6,ULK3,SELPLG,LNX2,SUMF2,TANC1,HAGH,API5,KLF6,PRPSAP1,TOLLIP,MAP2K2,DOT1L,ALKBH6,HLA-B,SGSH,NSF,H2AFX,DUSP11,PIEZO1,PDXK,TCOF1,AKNA,NAA60,SLC25A39,CSNK1D |
| 1.761e-07 | -15.55 | GSE34006_A2AR_KO_VS_A2AR_AGONIST_TREATED_TREG_DN | MSigDB lists | GSE34006_A2AR_KO_VS_A2AR_AGONIST_TREATED_TREG_DN | 187 | 56 | 17377 | 2626 |
SLC30A9,RMND5A,WASF2,USP7,FEZ2,NSMCE4A,TM9SF3,USP39,SIKE1,ABCB10,SECISBP2,MXD4,CCNL2,C2orf49,RLF,ZADH2,CRLF3,SYNRG,FAM8A1,REPS1,PIP4K2A,SSR1,SMC3,SIAH1,ZNF639,ZNF326,CDKN1B,ANAPC7,PTGES3,RNF19A,RNF135,SENP1,CFL1,SPSB3,HP1BP3,RBM15B,YTHDC1,PHF20L1,TSPYL4,MAP4K4,PTTG1IP,CBFB,KDM3A,POLG2,BTBD1,SUPT16H,ZNF689,UBXN2B,TPP2,PARG,CAB39,CNOT6,NANP,SASS6,CSNK1D,RHEBL1 |
| 1.761e-07 | -15.55 | GSE39382_IL3_VS_IL3_IL33_TREATED_MAST_CELL_UP | MSigDB lists | GSE39382_IL3_VS_IL3_IL33_TREATED_MAST_CELL_UP | 187 | 56 | 17377 | 2626 |
RMND5A,NCOR2,CDC40,REPS2,KIAA0100,GNPDA1,ADAM10,NACA,UROD,KIAA0232,NDUFA4,CREBL2,NENF,APH1B,STAM,FAM8A1,PIP5K1C,FKBP1A,TET3,VAV1,PRKD3,SIAH1,RNFT1,EFCAB11,PARL,CITED2,PCBP2,TACC3,ALDH9A1,CARS2,TDP1,PPP3CA,ARHGAP17,SNRNP200,POLR2L,TACC1,SELPLG,RAD51AP1,FRAT2,MCM2,MAT2A,CAT,MKNK1,PFDN5,OSBPL11,DDOST,BRWD1,OGT,CAB39,HMGB2,SCARB1,PDXK,ZMIZ1,RTN3,AP2S1,HIGD2A |
| 1.761e-07 | -15.55 | GSE17721_POLYIC_VS_CPG_2H_BMDC_UP | MSigDB lists | GSE17721_POLYIC_VS_CPG_2H_BMDC_UP | 187 | 56 | 17377 | 2626 |
SLC12A7,SEPHS2,MMACHC,H2AFZ,SYS1,LUZP1,IVNS1ABP,MRPS2,KLHL21,C16orf87,CERK,SMC6,MAPK14,RRP36,CAPN2,DTL,PA2G4,EXOSC1,ADCY9,CAPZA1,GLTP,MINPP1,TIPARP,PACS2,POC5,MYO5A,PREB,EBAG9,KDM3B,CYTH1,TRIM8,ATP13A1,FAM118B,SNRPB,TUBGCP5,WIPF1,MTX1,SMC2,SOX4,METTL22,KDM3A,MRPS14,BTBD1,DHX57,SUGP1,BRWD1,MFAP1,CORO1C,NFIL3,TBPL1,BAZ1B,MLYCD,PURA,ANAPC4,NUDT3,ADAM23 |
| 1.763e-07 | -15.55 | spindle assembly | biological process | GO:0051225 | 99 | 36 | 17256 | 2622 |
BCCIP,ZNF207,KIF3B,MZT1,XIAP,TPX2,KIF23,HAUS4,RACGAP1,RAB11A,HAUS2,BIRC2,TUBGCP2,FBXO5,KIFC1,STARD9,NEK6,ABRAXAS2,CEP63,RHOA,BIRC3,NEK7,ASPM,MYBL2,TUBGCP5,AURKB,KIF11,HAUS8,KIF2A,GOLGA2,BIRC5,GOLGA8A,CCDC69,CHEK2,TUBB,CSNK1D |
| 1.767e-07 | -15.55 | Autophagy - animal | KEGG pathways | hsa04140 | 127 | 44 | 7161 | 1149 |
TSC2,RAF1,PRKAA1,RRAGC,ATG2B,AKT1S1,BCL2L1,EIF2AK4,BECN1,PRKACA,CFLAR,ATG4A,VMP1,PTEN,MTMR4,ATG3,PIK3R2,DAPK1,ATG13,BCL2,MLST8,PDPK1,NRAS,ATG9A,RB1CC1,RAB7A,AKT2,KRAS,SUPT20H,MAP2K2,DAPK3,SH3GLB1,RHEB,MAPK3,CTSL,MTMR3,PPP2CA,TSC1,SNAP29,STK11,WIPI2,MAPK1,IGBP1,HRAS |
| 1.767e-07 | -15.55 | Autophagy - animal | KEGG pathways | ko04140 | 127 | 44 | 7161 | 1149 |
TSC2,RAF1,PRKAA1,RRAGC,ATG2B,AKT1S1,BCL2L1,EIF2AK4,BECN1,PRKACA,CFLAR,ATG4A,VMP1,PTEN,MTMR4,ATG3,PIK3R2,DAPK1,ATG13,BCL2,MLST8,PDPK1,NRAS,ATG9A,RB1CC1,RAB7A,AKT2,KRAS,SUPT20H,MAP2K2,DAPK3,SH3GLB1,RHEB,MAPK3,CTSL,MTMR3,PPP2CA,TSC1,SNAP29,STK11,WIPI2,MAPK1,IGBP1,HRAS |
| 1.782e-07 | -15.54 | cytokinesis | biological process | GO:0000910 | 83 | 32 | 17256 | 2622 |
PLK1,PDCD6IP,RHOA,SEPT9,RHOC,ACTR3,ANK3,JTB,MYH9,KIF23,SEPT8,RACGAP1,NUSAP1,CNTROB,AURKB,SEPT7,ANLN,STMN1,RHOB,RTKN,TMEM250,SEPT1,SNX18,RAB35,CEP55,PRC1,SEPT11,CHMP4B,VPS4A,ESPL1,CFL1,ANXA11 |
| 1.803e-07 | -15.53 | MECP2 (methyl-CpG binding protein 2) | protein interactions | 4204 | 150 | 50 | 17029 | 2761 |
MAX,TRIP12,NOP2,RPLP2,URB2,TWNK,RPL15,BLM,BRIX1,DDX56,SMC3,CDC42,NVL,RPL17,NOC2L,H2AFY,RPF2,YBX1,DDX31,CREB1,SMARCE1,DNMT1,ZNF800,TERF2,SP3,PLK1,RPL29,DDX24,HPDL,NOL8,TEX10,GTPBP4,TOP3A,RIOX2,MKI67,RPL8,RCOR1,CBX3,RPL36,CAT,KPNA4,RPL32,DGCR8,HIPK2,BBX,CHMP4B,RBPJ,YY1,NKAPD1,PDCD11 |
| 1.807e-07 | -15.53 | GENTILE_UV_HIGH_DOSE_DN | MSigDB lists | GENTILE_UV_HIGH_DOSE_DN | 302 | 80 | 17377 | 2626 |
RAB14,TRIP10,RAF1,TSC22D3,C5orf30,CUL1,SLC25A44,CCNB1,ATP6V1B2,CHD1,STAM,PHC2,CRKL,TNFAIP8,ATP2A2,SIAH1,ATP13A3,NUP153,TARDBP,CHTOP,TIPARP,CTDSP2,RYBP,KLF10,NCK1,TLK1,LRBA,E2F3,SLBP,MCL1,CDC6,PITPNB,RAB1A,ZFAND5,MAT2A,DDX17,KRIT1,UBTF,KIF2A,RBMS1,KPNA2,COIL,ZNF146,NDUFV2,PKP4,GNE,KIF23,JMJD6,RAB11A,PNO1,MLX,PDCD10,MBD2,TPST1,AHDC1,MAML1,PIKFYVE,MORC3,GINS1,NASP,TNFAIP3,AMD1,USP10,ISG15,FADD,RHOB,MTMR3,GNA12,SERTAD2,UAP1,MFAP1,NFIL3,MAPK6,SIAH2,DUSP11,MRFAP1L1,HMGB2,SRSF3,ACADM,ZMIZ1 |
| 1.808e-07 | -15.53 | ubiquitin-like protein transferase activity | molecular function | GO:0019787 | 473 | 115 | 17224 | 2647 |
MIB2,UBE2E2,MPHOSPH8,TRAF7,TRIM11,UBR2,XIAP,UBE2Q1,UBE2Z,KLHL18,CUL1,NHLRC3,UBE2I,BIRC2,ANKIB1,RNF103,FBXO22,ZER1,FANCL,MDM2,FBXL6,CDC42,SIAH1,ATG3,FBXW2,TTC3,MARCH2,RNF19A,RNF26,SPSB3,RLIM,PRPF19,BIRC3,RBX1,VHL,RNF25,CUL3,KIAA1586,UBE2V1,TOPORS,BRCA1,CDC23,CCNF,TRIM28,RAD18,NSMCE2,UHRF2,RNF38,TRIM32,KLHL42,FBXL3,SMURF1,ZNF598,CBX4,ZNF720,UBE2D3,RMND5A,TRIP12,KLHL21,SHPRH,ZFP91,UFC1,CBLL1,BRAP,ZNRF3,UBE4A,WWP2,DTL,RFWD3,FBXO3,HERC3,RNF121,UBE2Q2,KLHL20,MED10,KLHL5,HUWE1,ZNRF2,HDAC7,FBXO7,PPIL2,FEM1B,LTN1,FBXL7,UBE3B,UBE3C,RNF135,FBXL19,LRSAM1,UBE2M,RNF5,UBE2QL1,LONRF3,TNFAIP3,RFFL,FBXO9,ANAPC2,SYVN1,UBE4B,FBXO21,ZNF862,KEAP1,FBXO41,BIRC5,KLHL15,DTX4,KBTBD7,SIAH2,PIAS2,PPP1R11,RNF14,UBE2C,RNF139,ANAPC4,RNF114 |
| 1.821e-07 | -15.52 | GSE18791_UNSTIM_VS_NEWCATSLE_VIRUS_DC_10H_UP | MSigDB lists | GSE18791_UNSTIM_VS_NEWCATSLE_VIRUS_DC_10H_UP | 178 | 54 | 17377 | 2626 |
BCCIP,HIVEP3,NDUFA5,TP53RK,PPCS,CDC40,GXYLT1,PHF23,KLHL21,URB2,CXXC1,KIAA0232,CERK,PLXNA1,LRRC14,ZNF420,EXOSC7,MED8,GATC,NOL11,SUV39H2,MRPS27,MRPL34,FAM89B,GEMIN6,TAF5L,ACAD8,ASB6,NOL12,POLR2I,ZNF559,CSRP1,TACC1,NUDT4,EHMT1,POLR2D,ATXN1,FRAT2,DDX20,C9orf40,SLTM,IRF5,HAUS8,MFN2,FBXO21,ZNF317,CDCA4,EIF4ENIF1,MRFAP1L1,TRIM32,PTPDC1,RRS1,HRAS,ZC3HC1 |
| 1.824e-07 | -15.52 | MRPL14 (mitochondrial ribosomal protein L14) | protein interactions | 64928 | 47 | 23 | 17029 | 2761 |
PPIF,RPS15,MRPL9,SARNP,MRPL39,TUFM,CUL3,MRPS10,NDUFA4,MRPL16,NDUFA7,MRPS14,MRPL19,MRPL50,MRPL2,ETS2,HNRNPR,DUT,ZNF746,MRPL40,MRPL13,HNRNPDL,ZC3H3 |
| 1.858e-07 | -15.50 | G2/M Transition | REACTOME pathways | R-HSA-69275 | 182 | 58 | 10287 | 1696 |
FGFR1OP,MAPRE1,PPP1R12A,FOXM1,DYNLL1,DCTN2,CENPF,TPX2,CUL1,HAUS4,CCNB1,CDK11B,PRKACA,PSMD9,HAUS2,TUBGCP2,LIN9,PSMD2,RAB8A,PSMD1,PSMA6,CCNA2,CCP110,CENPJ,GTSE1,FBXL7,CDC25B,CEP63,DCTN1,PLK1,PSMA8,RBX1,MYBL2,TUBGCP5,PSMB7,PSMA1,PKMYT1,BORA,PSMB9,CDK11A,PSMB3,PSMC4,OPTN,HAUS8,PPP2CA,PCM1,RPS27A,PSMD8,PSMD3,ODF2,SSNA1,NDE1,RBBP4,CDK2,CCNB2,PSMC1,TUBB,CSNK1D |
| 1.869e-07 | -15.49 | cytoplasmic translation | biological process | GO:0002181 | 64 | 27 | 17256 | 2622 |
RPL29,CYLD,RPLP2,RWDD1,EIF3D,GSPT2,RPL6,RPL38,RPL8,RPL15,EIF4H,RPL27A,RBM4,EIF3A,MCTS1,RPL36,RPL11,MRPL2,RPL32,RPL17,EIF2D,FTSJ1,RPLP1,RPL19,EIF5,RPS26,RPL22L1 |
| 1.877e-07 | -15.49 | positive regulation of macromolecule biosynthetic process | biological process | GO:0010557 | 1686 | 330 | 17256 | 2622 |
ZNF496,H2AFZ,CXXC1,HEXB,YTHDF3,CCNL2,EDRF1,PARK7,GLMP,USF1,NOL11,DNM2,ECD,SENP1,CDC5L,KLF10,AATF,GABPA,AKT2,TOPORS,USP22,AURKB,CBFB,RFC2,ARF4,STOML2,DOT1L,MAP3K4,HHEX,SMAD2,RPS27A,AXIN1,OGT,RNASEL,TFDP2,SMAD1,ARRB2,E2F2,NMD3,HDAC2,SVIP,DDX58,HIVEP3,HSPH1,CHTF18,PRKAA1,DHX9,EZH1,EIF2AK4,PSMD9,PARN,PSEN1,METTL3,CDC73,DDRGK1,TFAP4,FOXN2,MYDGF,PABPC1,NUP85,NSUN4,EIF5A,FOXK1,MTA2,MYBL2,BCLAF1,EXOSC9,ARID1A,ADRB2,ELK1,FXR1,KDM3A,MAP2K2,CCT8,XRCC5,SERTAD2,GOLGA2,ETS2,SETD3,RBMX,PIAS2,PPP3R1,CEBPG,YY1,MAP3K5,RNF14,CDK2,EGLN1,RHOG,KARS,TRERF1,IVNS1ABP,RPS6KA1,RAF1,EIF3D,MAGED1,RAC1,CREBL2,APP,CCNA2,SHC1,SP100,GMEB1,LPIN2,MRPS27,MAVS,RBM15,ATF2,RPRD1B,CDK12,CCT2,PSRC1,BRD4,RFC3,CDC123,KAT7,WBP2,POLR2D,CIRBP,E2F3,EDF1,MEF2D,SERP1,TRIM28,SUPT16H,DDX17,TAF2,VEZF1,SAFB,HIPK2,STAT1,TICAM1,ATF6,ATMIN,POU3F2,MECP2,TCF3,HABP4,ABHD14B,WDR5,BLM,ETS1,FOXO3,MAD2L2,WWP2,GTF2F1,CCNK,PRDM4,CARF,CITED2,CREB1,NCOA2,PPP3CA,KAT2A,NEK7,RFXANK,ILF3,ZP3,KLF6,PICALM,FADD,GPS2,PITX1,TFDP1,PML,DDX5,HMGB2,CD81,USF2,YWHAH,RORB,CCNC,ZBED3,ZNF76,IER2,HNRNPAB,THOC1,AGRN,AAMDC,KMT2E,GPBP1L1,FAM129A,SIRT2,MAPK14,CREM,TET3,PCNA,GLIS2,EIF4A3,ZNF639,ETV6,PIK3R2,MYBL1,MTPN,ARID4A,CARM1,ELOF1,RYBP,SP3,DEAF1,NCK1,VHL,MRPL12,UBE2V1,LRP5,BRCA1,EAF2,SOX4,USP21,UBTF,PAF1,E2F4,ZNF268,CHEK2,DVL1,POT1,PSMC1,ZNF564,PPP1R12A,CHCHD2,CTCF,MEF2A,CDK13,PPP3CB,THRAP3,RLF,ASXL2,CRLF3,ARID1B,SUB1,RB1,MLX,NFATC3,MED10,SSBP3,ZNF746,CTR9,ICE2,RBM3,YBX1,MDFIC,MAML1,ERLIN1,LDB1,GBA,UTP15,RTF1,EIF2A,NFATC2IP,IRF5,CAND1,RXRB,PSMC4,TBPL1,NLRC5,NUP62,ZFP90,RUVBL2,SMARCD1,TCF12,ASH1L,FOXM1,SMARCA4,PLAGL2,IRF3,PCBP1,PAIP1,HNRNPA2B1,RRN3,NRF1,NVL,PIN1,TARDBP,F2R,DVL2,CHP1,MOSPD1,POU2AF1,POLR2G,NFATC2,RPS9,RBL1,SCAP,STAT6,ARNTL,NCOA1,AKNA,MAPK1,SMAD4,NAT14,SLC30A9,BCL2L12,DNAJC2,EYA1,CDT1,AGO2,DBF4,KLF13,PAWR,NKRF,HMGN3,PAGR1,FASTKD3,IRF4,BRD7,ARHGEF2,SS18L1,PTGES3,STAT3,TGFB1,COA3,DCAF6,RHOA,HMGN1,HMGN5,PRKDC,PRMT2,MEN1,TFEB,MAPK3,ATAD2,TFE3,E2F1,KMT2B,PKD2,RBPJ,NR2F2,ZMIZ1,HRAS,IFI16 |
| 1.882e-07 | -15.49 | SNRPA1 (small nuclear ribonucleoprotein polypeptide A') | protein interactions | 6627 | 146 | 49 | 17029 | 2761 |
SART1,CDC40,CYLD,XAB2,SF3B1,SUZ12,DCTN2,THRAP3,SNRPD3,CDC73,SF3B2,SNUPN,PSMA6,HUWE1,UCHL5,EFTUD2,BUD31,YBX1,ICE2,TARDBP,AQR,HNRNPM,PRPF19,CDC5L,SNRNP200,SNRPB,PPIE,SF3B6,POLR2D,CUL3,CRNKL1,PRPF3,SEPT7,MCM2,SF3A2,SNRPA,DHX15,PSMB3,SRSF1,GEMIN5,SYNCRIP,DDX5,PRPF4,PSAP,ISY1-RAB43,SNRPG,SNRNP70,SMURF1,COIL |
| 1.891e-07 | -15.48 | HIST3H3 (histone cluster 3 H3) | protein interactions | 8290 | 251 | 73 | 17029 | 2761 |
HNRNPAB,PHRF1,SUZ12,NSD3,KIF2C,TAF6L,CHD1,PHC2,HNRNPA2B1,MDM2,KDM2A,EIF4A3,MTA1,NOC2L,TAF5L,DNMT1,SAP30,KDM3B,BIRC3,EHMT1,PCGF6,AURKB,SUPT20H,PBRM1,DIDO1,MCM2,KMT2C,KDM1B,MBD3,TRIM28,ASF1B,CHAF1A,DOT1L,TAF2,KIF2A,JAK1,HNRNPR,TONSL,PPM1G,CBX4,SMNDC1,HDAC2,PPIB,MEF2A,WDR5,CDC73,MCM5,ZNF746,ANP32A,BRD7,H2AFY,AFF1,AHDC1,NAP1L4,CREB1,ORC3,NCOA2,KAT2A,ZMYND11,MTA2,MIER1,RCOR1,MEN1,CBX3,KPNA1,ATAD2,BIRC5,TAF12,RBBP4,TAF6,CD81,SGF29,IPO4 |
| 1.893e-07 | -15.48 | GO_POSITIVE_REGULATION_OF_LIGASE_ACTIVITY | MSigDB lists | GO_POSITIVE_REGULATION_OF_LIGASE_ACTIVITY | 108 | 38 | 17377 | 2626 |
GCLM,GORASP1,CUL1,CCNB1,DCUN1D4,PSMD9,FBXO5,PSMD2,PSMD1,PSMA6,PTEN,PIN1,ANAPC7,PLK1,PSMA8,PSMB7,PSMA1,ANAPC2,TOPORS,DCUN1D5,CDC23,RAB1A,PSMB9,PSMB3,MASTL,PSMC4,CDC16,MID1IP1,CDC27,GOLGA2,RPS27A,PSMD3,AXIN1,PSMD8,UBE2C,XRCC4,PSMC1,ANAPC4 |
| 1.901e-07 | -15.48 | GSE12392_CD8A_POS_VS_NEG_SPLEEN_IFNB_KO_DC_DN | MSigDB lists | GSE12392_CD8A_POS_VS_NEG_SPLEEN_IFNB_KO_DC_DN | 192 | 57 | 17377 | 2626 |
POLA2,CYTIP,IER2,MAPRE1,EWSR1,SCOC,MRPS15,UQCR10,SRSF6,RRM1,PAWR,CDIPT,CDK11B,METTL3,RNF103,EEF2K,DECR1,PCNA,IARS,RALB,ATP13A3,PPP6C,TIMELESS,SUCLG2,RPN2,SLC35C2,SLC12A2,STRAP,TMEM14C,PPAN,ELOVL5,BRD4,TMEM115,MAPRE2,PRKDC,ANKRD33B,SELPLG,ZMYND11,PPP1R21,SLC16A7,ADRB2,SRSF5,ICAM2,KLF6,SERP1,FKBP3,PRIM1,ATP1A1,DDOST,STAT6,SAFB,DTD1,MRFAP1L1,DDX5,TOB1,RAB3IL1,VPS29 |
| 1.905e-07 | -15.47 | HECW2 (HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2) | protein interactions | 57520 | 297 | 83 | 17029 | 2761 |
ZNF207,TSC2,ALKBH5,YTHDF3,CSNK2A1,PHC2,SPINDOC,SH3BP1,TAF5L,TECR,MOB1A,CHTOP,ZC3H3,CFL1,SEH1L,SRSF10,MIOS,PSMB7,SUPT20H,WBP1,DIDO1,PBRM1,DCUN1D5,CDC23,USP21,ARF4,EIF3H,RAD54B,CDC16,DUS3L,CEP55,ARRDC1,GLCCI1,SINHCAF,CBX4,UBE2D3,PPIB,HSPH1,NSMCE4A,MECP2,CDT1,CENPF,CYCS,ASXL2,TUBGCP2,HMG20A,SPAG5,NPLOC4,CCNK,ERV3-1,EXOSC7,DNAJC8,CTNNBL1,CTR9,AHCY,MRM3,EEF1D,RBM15B,CYFIP1,NTPCR,ZFP64,KAT2A,DDX24,RBM42,USP10,MAP7D1,FAM133B,MPG,ZP3,MACF1,SF3A2,PSMB3,PHF6,CBX3,MBIP,KPNA1,CDC27,L3MBTL3,OSBPL8,ZC3H7B,CABIN1,ANAPC4,ZSWIM6 |
| 1.919e-07 | -15.47 | GO_NEGATIVE_REGULATION_OF_CYTOSKELETON_ORGANIZATION | MSigDB lists | GO_NEGATIVE_REGULATION_OF_CYTOSKELETON_ORGANIZATION | 206 | 60 | 17377 | 2626 |
WASF2,ZNF207,KIF3B,CHMP2A,MAPRE1,GMFG,ADD1,DCTN2,CIB1,TPX2,XIAP,KIF23,MYH9,RACGAP1,HAUS4,CCNB1,TWF2,STMN1,RAB11A,TUBGCP2,BIRC2,HAUS2,SPAG5,FBXO5,KIFC1,STARD9,SMC3,NEK6,CAPZA1,PRC1,ARHGEF2,CORO1A,CEP63,SPTAN1,RHOA,BIRC3,ASPM,NEK7,MYBL2,GMFB,TUBGCP5,EZR,CAPZA2,AURKB,BRCA1,CCNF,KIF11,HAUS8,KIF2A,MID1IP1,GOLGA2,CHD3,BIRC5,MAP4,ARAP1,CHEK2,WDR62,ESPL1,CSNK1D,TUBB |
| 1.947e-07 | -15.45 | RBM4 (RNA binding motif protein 4) | protein interactions | 5936 | 163 | 53 | 17029 | 2761 |
NOP2,URB2,SUZ12,AGO2,DHX9,CUL1,EBNA1BP2,BRIX1,SEC16A,ZNF121,RPA2,RBM23,ZNF420,NVL,RBM34,POP7,RPF2,DDX31,AQR,PABPC1,CARM1,HNRNPM,CDC5L,RPP25,RBM42,DDX24,POLK,STRIP1,TEX10,HNRNPF,GTPBP4,UTP15,CUL3,BUD13,CENPU,MAPK3,RPA1,DDX17,CAND1,NSA2,ZNF317,RPL32,TBL3,HNRNPH3,PPM1G,CDCA5,DDX5,COPS6,RRS1,CDK2,PDCD11,IPO4,ZBTB24 |
| 1.950e-07 | -15.45 | Cell Cycle | WikiPathways | WP179 | 105 | 38 | 5312 | 837 |
MCM10,PTTG1,DBF4,ARF1,ORC1,CCNB1,MAD2L2,RB1,CCNA2,MDM2,PCNA,HDAC7,MCM5,CDKN1B,CDC25B,ORC3,PLK1,TGFB1,PRKDC,E2F3,CDC6,PKMYT1,MEN1,MCM2,RBL1,E2F4,TFDP1,E2F1,YWHAZ,CHEK2,YWHAH,CDK2,CCNB2,E2F2,ESPL1,SMAD4,HDAC2,CDKN2A |
| 1.964e-07 | -15.44 | UBE2A (ubiquitin conjugating enzyme E2 A) | protein interactions | 7319 | 202 | 62 | 17029 | 2761 |
UNK,PDCD6IP,ANXA6,UBR2,SHPRH,EIF3D,UBXN1,XIAP,OLA1,KIF23,CSNK2A1,KIF2C,THRAP3,POMP,UBQLN2,KCMF1,MYL6B,CDK5,HNRNPA2B1,RPA2,CD59,MDM2,PCNA,FBXL6,EIF4A3,PIN1,AP1M1,ARHGEF2,YBX1,TTLL12,LRRC59,FTSJ3,DCTN1,NIPSNAP1,PRPF19,EIF5A,LARS,UBQLN4,RPL35,SNRPB,BTAF1,UBE2V1,DNAJA1,TOMM40,RPS9,DHX15,NSA2,KEAP1,SYNCRIP,RAD18,HNRNPR,PSMD3,PRDX5,ACAT1,SRSF3,RBBP4,CDK2,BRD9,SLF1,HNRNPDL,AAAS,CDKN2A |
| 1.982e-07 | -15.43 | GSE411_100MIN_VS_400MIN_IL6_STIM_MACROPHAGE_DN | MSigDB lists | GSE411_100MIN_VS_400MIN_IL6_STIM_MACROPHAGE_DN | 183 | 55 | 17377 | 2626 |
MIF,GCLM,TOMM20,GNPNAT1,RWDD1,NDUFB6,OLA1,TMEM165,ABHD14A,JMY,NUP205,CD320,DNAJB9,RAD23A,KRR1,LYAR,DUS4L,UTP18,AHSA1,ATIC,PPIG,BANF1,BTF3L4,NSFL1C,NAA50,GEMIN6,GTSE1,SEPT11,AHCY,ALDH18A1,METTL1,CREG1,NOL8,ILF3,CAMSAP1,FAM133B,KRAS,ARL5B,GFER,MAK16,TWISTNB,DOT1L,GEMIN5,ALG3,KIF2A,SLCO4A1,KPNA1,HINT1,SYNCRIP,CERS6,TBL3,TFDP1,COPS6,MRPL3,SSSCA1 |
| 1.982e-07 | -15.43 | GSE22935_24H_VS_48H_MBOVIS_BCG_STIM_MACROPHAGE_DN | MSigDB lists | GSE22935_24H_VS_48H_MBOVIS_BCG_STIM_MACROPHAGE_DN | 183 | 55 | 17377 | 2626 |
WASF2,SRM,RMND5A,C19orf53,GOLPH3L,SYS1,SLC41A1,MRPS26,B4GALT1,TM9SF3,PRPF39,PDCD7,METTL3,SEC11A,RPA2,SMC3,GATC,EIF4A3,RALB,PELO,EIF5,TMEM14C,ELOF1,FDFT1,USP34,PPAN,CCT2,NTPCR,POLR2I,AATF,FOPNL,PIP4K2C,ZNF574,HEBP2,C1orf35,LRRC8A,BUD13,MCFD2,KRTCAP2,GFER,TSR2,DHX57,CLNS1A,UBTF,YIF1A,PPP2CA,RPS14,TFDP1,ARAP1,SLC16A1,MLYCD,PPP6R2,YY1,CPEB2,SMAD4 |
| 1.982e-07 | -15.43 | GSE22432_CONVENTIONAL_CDC_VS_PLASMACYTOID_PDC_UP | MSigDB lists | GSE22432_CONVENTIONAL_CDC_VS_PLASMACYTOID_PDC_UP | 183 | 55 | 17377 | 2626 |
NUP188,H2AFZ,RRP15,SUCLG1,NDUFAF2,MUM1,TCF3,TMX4,TMEM109,DNAJC24,KIF23,TOP2B,C19orf48,PNO1,LMNA,SAC3D1,RPN1,RAP1A,UTP18,ATIC,MCM5,PIN1,PRC1,MSH2,SUCLG2,KNTC1,PTGES3,GLE1,TOP1MT,NUDC,METTL1,ADAM17,PRIM2,CDC123,EMB,WDR18,ARHGDIB,PITPNB,TOMM40,EIF3G,UBTF,SH3BP5,KIF2A,NAP1L1,HSPBP1,TTC13,HINT1,SEC61A1,NIP7,PPA2,PRMT7,MBOAT1,RRS1,ZMAT3,GCSH |
| 1.998e-07 | -15.43 | OFD1 (OFD1, centriole and centriolar satellite protein) | protein interactions | 8481 | 265 | 76 | 17029 | 2761 |
KARS,FGFR1OP,COPA,LUZP1,RAB11B,DYNLL1,ENSA,CNTROB,CCNB1,FARSA,PA2G4,CCNA2,IARS,TXLNA,DNM2,GPATCH1,CEP63,TP53BP2,STRAP,POC5,CDC37,PLK1,CCDC57,LARS,CCDC138,FOPNL,RRM2,AURKB,DNAJA1,USP22,ERC1,GIGYF1,HSPA4,EIF4ENIF1,HINT1,CCDC14,PDRG1,CEP55,SASS6,CEP170B,MCM10,MAPRE1,FLOT1,RRM1,KLC1,RAB6A,CNOT11,HAUS2,SPAG5,CEP104,PSMD2,TIGAR,CENPJ,CTPS1,ICE2,NAP1L4,TTLL12,LUC7L2,NUDC,RPAP3,ELL2,DENND4C,ADSL,COMMD4,CIP2A,HAUS8,COMMD3-BMI1,PCM1,QARS,ODF2,EXOC4,KIAA1328,TCOF1,NDE1,IDH3B,CDK2 |
| 2.040e-07 | -15.41 | MORI_PLASMA_CELL_UP | MSigDB lists | MORI_PLASMA_CELL_UP | 50 | 23 | 17377 | 2626 |
TMEM39A,WDYHV1,GPR89A,SCFD2,SSR2,HTATIP2,NANS,DNAJB9,EBP,DERL1,TRAM2,RPN1,SURF4,MAGT1,DDOST,STT3A,RRBP1,SLC44A1,SPCS3,OSTC,LMAN1,GPR89B,TMED2 |
| 2.041e-07 | -15.40 | GSE14000_UNSTIM_VS_4H_LPS_DC_TRANSLATED_RNA_UP | MSigDB lists | GSE14000_UNSTIM_VS_4H_LPS_DC_TRANSLATED_RNA_UP | 174 | 53 | 17377 | 2626 |
NDUFA5,COX15,CMAS,MRPL9,NOP2,HNRNPAB,TRERF1,GXYLT1,TSC22D3,TMX3,RACGAP1,TMEM165,COMMD8,JMY,HEATR5B,MOAP1,C12orf10,RAP1A,DUT,MRPL34,MSH2,MRPS27,SOCS6,FBXW2,CAMK2G,MSH6,TERF2,CSTF1,SAP30,FAM172A,ZNF500,FAM118B,MBLAC2,FRAT2,LRRC8A,BCLAF1,MTMR12,UBE4B,C9orf40,FOXRED1,BBS12,TSC1,FBXO21,PWWP2B,PEX5,PALB2,PFDN4,PROSER1,ZFP90,COPS6,MAP3K5,RRS1,LONP2 |
| 2.064e-07 | -15.39 | YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_13 | MSigDB lists | YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_13 | 156 | 49 | 17377 | 2626 |
PPIB,NDUFA5,CHMP2A,C9orf78,COX5B,H2AFZ,DAP,UQCR10,CUTA,TKT,LAGE3,TMED3,SLC35B2,TCF19,MIEN1,LYRM2,REEP5,POLR3K,PARK7,HDDC2,CD320,EBP,PSMA6,NDUFA2,RBM3,TAGLN2,MRPL11,NDUFA3,S100A6,ELOF1,GPX4,ABCC1,TIMM8B,GUK1,CSRP1,FAM49B,OGFR,FKBP3,ECH1,CAT,DAP3,MRPL27,FAM3C,DBI,PQBP1,SSNA1,SNRPG,MRPL13,VPS29 |
| 2.071e-07 | -15.39 | GSE37532_WT_VS_PPARG_KO_LN_TCONV_DN | MSigDB lists | GSE37532_WT_VS_PPARG_KO_LN_TCONV_DN | 165 | 51 | 17377 | 2626 |
RMND5A,PTMS,LIME1,H2AFZ,CDCA3,GMCL1,NUF2,FKBP2,DAZAP2,NCAPG,REEP5,HNRNPA2B1,C12orf10,PCNA,CLIC4,CCNA2,CCDC50,DPYSL2,PPP1R8,PRC1,GTSE1,TAP2,MAST2,CDC25B,PDIA6,S100A6,TACC3,SNX25,PPT1,NEK7,NUDT4,MKI67,CDCA2,EDF1,SMC2,SHCBP1,KIF11,PSMB9,ASF1B,CDKN2AIPNL,STT3A,BIRC5,MYO18A,ITGB1,PTPN7,CBWD1,HMGB2,ANP32E,ATP6V0C,GEN1,YWHAH |
| 2.100e-07 | -15.38 | PRDX3 (peroxiredoxin 3) | protein interactions | 10935 | 68 | 29 | 17029 | 2761 |
UNK,COX15,UBQLN4,XIAP,CUL3,CUL1,SMC6,NUSAP1,GORASP2,CCNB1,MCM2,VDAC1,ATP5PF,SDHA,MARK2,PARK7,BIRC2,PRDX1,MAPK3,PCNA,NEK6,CDC42,PRDX3,UCHL5,UBA5,H2AFX,CDK2,RPS6KC1,TERF2 |
| 2.128e-07 | -15.36 | GO_REGULATION_OF_CELL_DIVISION | MSigDB lists | GO_REGULATION_OF_CELL_DIVISION | 259 | 71 | 17377 | 2626 |
ZNF207,CHMP2A,PDCD6IP,PTTG1,CSNK2A1,SIRT2,CCNB1,BECN1,CALM2,NEK6,CDC42,PIN1,KIF14,CDC25B,PLK3,PLK1,CUL3,LRP5,NUSAP1,CDC6,AURKB,PKMYT1,CDC23,RAB1A,CHMP2B,ANLN,CDC16,KIF18B,NSMCE2,CHMP4B,XRCC3,VPS4A,GEN1,KIF3B,PKP4,KLHL21,PHB2,GORASP1,CENPF,CIB1,KIF23,CDK13,RACGAP1,BLM,MAD2L2,FBXO5,PDXP,RB1,CCP110,PTEN,MSH2,H2AFY,YBX1,KNTC1,TGFB1,PPP1R9B,RHOA,ASPM,KIF11,BORA,DAPK3,SH3GLB1,CAT,CDC27,GOLGA2,BIRC5,CDCA5,UBE2C,TERF1,ESPL1,ANAPC4 |
| 2.144e-07 | -15.36 | RICKMAN_TUMOR_DIFFERENTIATED_WELL_VS_POORLY_UP | MSigDB lists | RICKMAN_TUMOR_DIFFERENTIATED_WELL_VS_POORLY_UP | 216 | 62 | 17377 | 2626 |
IMMT,ZNF496,TOMM20,PKP4,DNMT3A,PNISR,SRSF6,CHD1L,CENPF,RMI2,TMEM97,STARD7,MYNN,GMCL1,GTF3A,SRRT,SPAG5,C2orf68,LRRC14,AHCTF1,RPL17,TRA2B,ANP32A,FBL,TNRC18,FAM171A1,MSH6,EEF1D,SMC4,USP34,GINS1,EIF3L,SNRNP200,NASP,ATP2C1,ZBED5,BOLA1,CBFA2T2,CHCHD6,EML4,USP21,MAT2A,SRSF1,EPB41,DDX17,MAN2A2,GNAS,ZNF180,NAP1L1,TTLL4,LUC7L3,OGT,IARS2,MDH1,SRSF3,TFDP2,GLCCI1,CHPT1,TRAF5,TERF1,PDCD4,FUBP1 |
| 2.144e-07 | -15.36 | GSE22432_MULTIPOTENT_PROGENITOR_VS_CDC_DN | MSigDB lists | GSE22432_MULTIPOTENT_PROGENITOR_VS_CDC_DN | 188 | 56 | 17377 | 2626 |
NDUFV2,NUP188,H2AFZ,NOP2,RRP15,DEPDC1,SUCLG1,NDUFAF2,PHB2,TMX4,LAMTOR3,KIF23,PTP4A3,MXD4,OAT,C19orf48,SLC20A1,ANKRD39,LMNA,FANCL,MRPL50,IRF4,PA2G4,RAP1A,EXOSC7,UTP18,MCM5,ATP13A3,GEMIN6,PCYT2,PTGES3,FYTTD1,TDP1,AATF,EID1,NUDT4,PBK,LRRC8A,NFATC2,PITPNB,BORA,PICALM,CCT8,SERP1,EIF3G,UBTF,NAP1L1,SEC61A1,BRWD1,HINT1,LSM6,NIP7,ZNF330,SLC16A1,RRS1,GCSH |
| 2.144e-07 | -15.36 | GSE36009_WT_VS_NLRP10_KO_DC_LPS_STIM_UP | MSigDB lists | GSE36009_WT_VS_NLRP10_KO_DC_LPS_STIM_UP | 188 | 56 | 17377 | 2626 |
SART1,IMMT,TRIP12,CHERP,GORASP1,ZCCHC8,PRKCSH,CAST,MRPS26,AGFG1,MIEN1,LMNA,XPR1,PIP5K1C,WRNIP1,ZBTB45,CENPJ,PRC1,CS,RPN2,CLDND1,CREB1,S100A6,MSH6,GPX4,ATP6V1G1,RBM42,KAT7,NSDHL,OXR1,PARP4,UBE2V1,PLEC,ARID1A,RAB22A,MTR,NECAP2,ALKBH6,BRD2,CERS6,NSMCE2,CORO1C,HIPK2,EXOC4,ACLY,BCL7C,SLC25A19,ADAM9,FAM126A,XRCC3,KPNA2,TRIM32,PSAP,ZMIZ1,CDK2,CCNB2 |
| 2.178e-07 | -15.34 | nuclear-transcribed mRNA catabolic process | biological process | GO:0000956 | 201 | 59 | 17256 | 2622 |
RPS15,RPS2,RPLP2,GSPT2,RBM8A,RPL15,THRAP3,CNOT11,PARN,PAIP1,PRPF18,TUT4,CNOT3,EDC3,RPL23A,RPL11,CSDE1,EXOSC7,RPL17,EIF4A3,PELO,EXOSC1,DCP1A,RPL19,UPF2,CNOT6L,PABPC1,SAMD4B,RPL29,RPL35,EXOSC6,POLR2G,RPL6,POLR2D,RNPS1,RPL8,RPL38,RPS10,RPS24,EXOSC9,RPL27A,PATL1,RPS9,RPSA,RPL36,CNOT9,RPL37,PPP2CA,UPF1,RPL32,RPS27A,LSM6,RPS14,NT5C3B,RPLP1,DDX5,CNOT6,SMG9,RPS26 |
| 2.189e-07 | -15.33 | PHF8 (PHD finger protein 8) | protein interactions | 23133 | 61 | 27 | 17029 | 2761 |
USP7,TRIP12,CGAS,MRPS15,NOL8,SUMO2,ANAPC2,PLEC,CDC23,WDR5,BLM,APP,POLR2A,PI4K2A,TRIM26,CCNA2,CDC16,CDC27,NIP7,MRPS27,OGT,H2AFY,RPAP1,ANAPC7,RBPJ,MAML1,ANAPC4 |
| 2.194e-07 | -15.33 | QARS (glutaminyl-tRNA synthetase) | protein interactions | 5859 | 126 | 44 | 17029 | 2761 |
TCF12,KARS,MAPRE1,CYLD,FOXM1,TRMT6,DHX9,LAMTOR3,RPL15,CUL1,KCMF1,APP,CPNE3,RPL23A,HNRNPA2B1,IARS,HUWE1,PIN1,TXLNA,RTCB,RPL19,STAU1,LARS,TK1,PRRC2A,FAM118B,CUL3,KRAS,BRCA1,DNAJA1,PLEC,TOMM40,MCM2,RPL27A,ZFR,DDX17,RPL36,EPRS,C1orf131,H2AFX,XRCC3,DUSP11,MAP3K5,CDK2 |
| 2.218e-07 | -15.32 | KEGG_ALZHEIMERS_DISEASE | MSigDB lists | KEGG_ALZHEIMERS_DISEASE | 143 | 46 | 17377 | 2626 |
COX5B,NDUFA5,NDUFV2,NDUFS1,NDUFB6,ADAM10,UQCR10,NDUFA4,COX4I1,CYCS,PPP3CB,PSEN1,SDHA,APP,NDUFS7,NDUFS4,CALM2,CDK5,CAPN2,NDUFV1,NDUFA2,ATP2A2,NDUFB4,NDUFB9,NDUFS8,CYC1,NDUFA3,PPP3CA,ADAM17,APH1A,NDUFA7,NDUFB1,FADD,MAPK3,FAS,SDHB,IDE,COX7A2L,COX8A,PPP3R1,COX5A,UQCRH,ATF6,NDUFS5,MAPK1,CAPN1 |
| 2.229e-07 | -15.32 | GSE3982_NEUTROPHIL_VS_BASOPHIL_DN | MSigDB lists | GSE3982_NEUTROPHIL_VS_BASOPHIL_DN | 179 | 54 | 17377 | 2626 |
TCF12,CCNC,NDUFA5,DYNLL1,SRSF6,ABCC10,YTHDC2,GTF3A,PSMD1,ADD3,CTNNBL1,KLHL20,IARS,RNFT1,DPYSL2,DNAAF2,FUT8,NOC2L,YBX1,RPN2,COPS7B,TCEA1,NFU1,PTGES3,FBL,NUP85,SMC4,PRPF19,MAPRE2,POLR2G,ATP2C1,ADSL,OTUD3,API5,PRPSAP1,PEF1,TARS,ZFR,RHEB,CAND1,MAP3K4,FBXO21,HINT1,UAP1,TTC13,DUSP3,RPS27A,PTER,C1orf109,ITGB1,WDR7,ACAT1,ZDHHC7,CHPT1 |
| 2.229e-07 | -15.32 | GSE11864_UNTREATED_VS_CSF1_IN_MAC_UP | MSigDB lists | GSE11864_UNTREATED_VS_CSF1_IN_MAC_UP | 179 | 54 | 17377 | 2626 |
UBE2D3,ZNF296,GMFG,NOP2,RWDD1,PHB2,ENSA,KLF13,USP39,ABHD14B,FAM136A,NDUFS7,HDDC2,GOLM1,MTA1,ARHGEF1,RPL19,TAP2,CYC1,RNLS,HNRNPM,TGFB1,SAMD4B,PTPN18,RPL35,LONRF3,KIAA0040,NET1,GTPBP4,PSMA1,SRSF5,EAF2,PRKRA,OGFR,TAZ,RPS9,ZDHHC3,ARHGAP15,NSA2,DNAJC10,HHEX,HGS,SERTAD2,SMAD2,CCDC6,HIPK2,FASTK,MEGF9,KLHDC4,TSTD2,CHPF2,MZT2B,ZNF598,RNF139 |
| 2.229e-07 | -15.32 | GSE14308_TH1_VS_NAIVE_CD4_TCELL_UP | MSigDB lists | GSE14308_TH1_VS_NAIVE_CD4_TCELL_UP | 179 | 54 | 17377 | 2626 |
MBD1,CCNC,LUZP1,HJURP,RWDD1,MRPS15,PRKCSH,PPP1R15B,RBM8A,C19orf25,FLOT1,C5orf30,PXMP2,COMMD5,USP5,LYAR,SUB1,PCNA,TTC9C,MRPL34,BRI3,KIFAP3,MRPL48,LMAN1,SGCB,LRRC59,SRSF10,FAM172A,SEPT9,SNX2,HELB,METTL5,PSMA1,ANAPC2,PITPNB,PTTG1IP,ARPC1A,CCT8,GINS4,CAT,KIF18A,NSMCE2,GADD45B,TBPL1,MBOAT1,NDUFS5,RUVBL2,RRS1,WDR91,NDE1,WDR62,C11orf1,RAD51D,RHEBL1 |
| 2.230e-07 | -15.32 | MED20 (mediator complex subunit 20) | protein interactions | 9477 | 122 | 43 | 17029 | 2761 |
CCNC,RECQL,PHB2,GNPDA1,TKT,CYCS,DNAJB1,NCAPG,KCMF1,GTF2F1,RAD23A,FKBP1A,MED8,MED10,HUWE1,ARF5,RAD23B,AKR1B1,TRA2B,TCEA1,POLR1B,PDIA6,PPA1,TMED2,MED22,SPTAN1,ATP5IF1,RHOA,RPS10,GTPBP4,SRSF5,VDAC1,SLTM,POLR2A,ECH1,ARF4,TPD52L2,PDCD6,BIRC5,CORO1C,MED15,MDH1,SNRPG |
| 2.279e-07 | -15.29 | KEGG_UBIQUITIN_MEDIATED_PROTEOLYSIS | MSigDB lists | KEGG_UBIQUITIN_MEDIATED_PROTEOLYSIS | 130 | 43 | 17377 | 2626 |
UBE2D3,UBE2E2,TRIP12,XIAP,UBE2Z,UBE2Q1,CUL1,UBE4A,UBE2I,BIRC2,WWP2,HERC3,FANCL,MDM2,UBE2Q2,SIAH1,HUWE1,PPIL2,ANAPC7,UBE3B,UBE3C,UBE2M,PRPF19,UBE2QL1,BIRC3,RBX1,VHL,CUL3,ANAPC2,SYVN1,BRCA1,UBE4B,CDC23,KEAP1,CDC16,CDC27,PML,PIAS2,TRIM32,SMURF1,UBE2C,ANAPC4,DDB1 |
| 2.287e-07 | -15.29 | PSMD4 (proteasome 26S subunit, non-ATPase 4) | protein interactions | 5710 | 168 | 54 | 17029 | 2761 |
CYLD,MDH2,TCF3,UBXN1,DCTN2,LAGE3,FLOT1,CUL1,ATP5F1B,UBQLN2,PSMD9,APP,UBLCP1,RAD23A,PTPN2,HERC3,PSMD2,MDM2,PSMD1,PSMA6,CCNA2,HUWE1,GOT2,UCHL5,MCM5,RAD23B,AHCYL1,PDIA6,CCAR1,KDELR1,TXNL1,UBQLN4,IDH3A,PSMB7,PSMA1,BRCA1,CAPZA2,MCFD2,PSMB9,PSMB3,PSMC4,RPA1,TPD52L2,HSPA4,POLE,PSMD8,PSMD3,SIAH2,ATP5F1A,ECPAS,UBE2C,SMURF1,PSMC1,TERF1 |
| 2.291e-07 | -15.29 | ACTAYRNNNCCCR_UNKNOWN | MSigDB lists | ACTAYRNNNCCCR_UNKNOWN | 415 | 102 | 17377 | 2626 |
UBL3,IMMT,MAX,TSC2,TRIP10,UBR2,UQCR10,WDTC1,ZNF416,SIRT2,SND1,INO80E,USP48,HCFC1R1,STMN1,MRPL19,USP5,CSDE1,MRPL50,PA2G4,ZNF75D,ZNF420,AHCTF1,CD3EAP,PPP6C,MRPL34,TNPO2,NUP153,RNASEH2A,GPD1L,CFL1,ABCC5,PRPF19,LARS,APH1A,WBP2,CDC6,BRCA1,PRIM1,DUS3L,RPS27A,FTSJ1,DNAJC17,NCLN,PRPF4,AP2S1,ATXN7L2,HSPH1,CMAS,CDC40,SCAMP3,MRPL42,ZCCHC8,DCTN2,ADO,ARID5A,VPS45,CDCA3,RPL15,CBLL1,DCUN1D4,ASXL2,MYL6B,HMG20A,TFAP4,RNF121,PDCD10,ZNF449,SLC35B4,MRPL54,CLDND1,PCYT2,POLR1B,PABPC1,ZNF189,TMEM160,STAU1,KAT2A,RNASEH2C,POLK,RDH10,RPL6,TOP3A,FBXO9,RANGAP1,NFATC2IP,VKORC1,MTR,SFXN5,PSMC4,RDH11,MFN2,ADSS,DERL1,ZNF180,TMEM127,PCM1,TTC13,SLC38A7,TTLL4,MDH1,ESPL1 |
| 2.305e-07 | -15.28 | GSE33425_CD161_INT_VS_NEG_CD8_TCELL_UP | MSigDB lists | GSE33425_CD161_INT_VS_NEG_CD8_TCELL_UP | 193 | 57 | 17377 | 2626 |
UBE2D3,TCF12,UBL3,CMAS,ADAM10,IVNS1ABP,SRGN,YTHDF3,RRAGC,ASAH1,PPP3CB,DAZAP2,RGS2,BRIX1,CRLF3,PCBP1,SDHA,BCAP31,DNAJB9,WRNIP1,ERH,PRKD3,RAB8A,SMC3,VMP1,RNFT1,EI24,MDFIC,OSTF1,ARL5A,RNF5,EID1,NUDT4,EMB,SMU1,RCOR1,DNAJC9,TMEM147,DIDO1,PSMB9,SLTM,ARF4,MAGED2,PON2,AHNAK,RAB24,SAFB,PTER,U2SURP,ROCK1,ATP6V1C1,HEXA,YWHAH,TRAF5,PTDSS1,SMNDC1,PRPF4B |
| 2.307e-07 | -15.28 | GSE15271_CXCR4_POS_VS_NEG_GC_BCELL_DN | MSigDB lists | GSE15271_CXCR4_POS_VS_NEG_GC_BCELL_DN | 161 | 50 | 17377 | 2626 |
PRKAB1,FEZ2,SYS1,ANXA6,SRGN,TMX4,KLF13,B4GALT1,ZNRF3,MYO9B,GGPS1,LYN,MXD1,RNF103,XPR1,RAVER2,GOLM1,TMEM8A,NIPAL3,STAU1,PPP3CA,ABHD2,FOXK1,BIRC3,COQ10B,CIRBP,NFATC2,PNPLA8,ARID1A,TANC1,SOX4,POLG2,MATR3,MTMR3,TRIM26,AHNAK,ACOX1,MAFK,MYO18A,KBTBD7,WDR7,SAMD8,AKNA,USF2,RNF139,DCAF5,TOB1,MYL12B,CBX4,ZSWIM6 |
| 2.316e-07 | -15.28 | RLIM (ring finger protein, LIM domain interacting) | protein interactions | 51132 | 41 | 21 | 17029 | 2761 |
UBE2D3,UNK,UBE2E2,TNFAIP3,DNAJB2,UBXN1,LDB1,LNX2,TOLLIP,STMN1,MDM2,PDLIM1,SIAH1,LIMK1,RPS14,STAT6,AXIN2,SS18L1,TERF1,HDAC2,RLIM |
| 2.351e-07 | -15.26 | REACTOME_IMMUNE_SYSTEM | MSigDB lists | REACTOME_IMMUNE_SYSTEM | 880 | 188 | 17377 | 2626 |
UBE2E2,NUP188,TXN,TSC2,PRKCSH,TRIM11,TAP1,UBE2Z,UBE2Q1,CUL1,KIF2C,MAPK14,BIRC2,CALM2,RAP1A,PSMD1,NUP210,CDC42,EIF4A3,IL6ST,PIK3R2,AP1M1,DNM2,AP2B1,KIF22,NUP153,ASB6,SEH1L,PCBP2,MLST8,NRAS,NCK1,RBX1,AKT2,VHL,KIF15,WAS,RPS27A,PSMD8,TPP2,ITGB1,KPNA2,RNASEL,PSMC1,AAAS,DDX58,UBE2D3,SEC61G,KIF23,KLC1,MEF2A,RACGAP1,ITGB5,PSMD9,NUP205,VASP,UBE2Q2,CAPZA1,ORAI1,KIFAP3,BCL2,UBE3C,RNF135,LRSAM1,NUP85,MAPKAPK3,PSMA1,KRAS,CAPZA2,ICAM2,ELK1,EIF4G2,MAP2K2,ISG15,PSMB3,IRF5,PSMC4,SEC31A,KPNA1,CDC27,CSK,DUSP3,NLRC5,NUP62,CTSA,YWHAZ,CYLD,RPS6KA1,RAF1,UBR2,DYNLL1,RAC1,IRF3,BCL2L1,AP1B1,LYN,PRKACA,APP,CRKL,VAV1,PSMA6,MDM2,SHC1,SP100,PIN1,UBA5,NUP107,CDKN1B,TAP2,ANAPC7,MAVS,ATF2,DCTN1,SEC61B,BIRC3,PSMA8,RAB7A,RNF25,PSMB7,CUL3,NUP155,CDC23,ASB13,PSMB9,TOLLIP,PPP2CA,KIF2A,CDC16,JAK1,PPP2R5A,DDOST,SEC61A1,TAB2,PSMD3,STAT1,AP1S1,TICAM1,TRIM32,SMURF1,MAPK1,AP2S1,DYNC1LI2,OTUD5,KIF3B,TRIP12,RAE1,DCTN2,NUP54,SIKE1,ARF1,IP6K2,UBE4A,AKT1S1,FOXO3,HLA-A,PTPN2,KIF5B,FBXO3,IRF4,PSMD2,CTSS,KLHL20,PTEN,HUWE1,SEC24C,TANK,UBE3B,CREB1,MAP3K14,CNPY3,STAT3,UBE2M,PDPK1,ADAM17,TNFAIP3,ANAPC2,KIF11,FADD,MAPK3,HLA-B,KPNA4,KEAP1,KIF18A,PML,UBE2C,CD81,HRAS,ANAPC4 |
| 2.356e-07 | -15.26 | V$E2F1_Q4 | MSigDB lists | V$E2F1_Q4 | 226 | 64 | 17377 | 2626 |
UBE2D3,POLA2,WASF2,PRPF38B,ATXN3,CLSPN,ZCCHC8,RAB11B,PRKCSH,CXXC1,CHTF18,RMI2,CTCF,PRKACA,STMN1,FBXO5,HNRNPA2B1,RPA2,LYAR,RNF121,ERH,PCNA,SMC3,INTS7,PPP1R8,PELO,CDKN1B,NUP153,KNTC1,PCYT2,GPD1L,ARID4A,LUC7L2,EIF5A,SLC39A9,PPP1R9B,NASP,PRKDC,MIER1,E2F3,SREK1,FBXO9,SLBP,RTF1,CDC6,PKMYT1,OGDH,BORA,ARPC1A,TRIM28,SRSF1,HMGN2,PRIM1,CBX3,DDX17,DGCR8,GPS2,E2F1,FAU,BTBD10,SASS6,ARRB2,CBX4,DDX42 |
| 2.400e-07 | -15.24 | import into nucleus | biological process | GO:0051170 | 121 | 41 | 17256 | 2622 |
POLA2,NUP188,TSC2,PHB2,RAE1,NUP54,SNRPD3,RPAIN,SNUPN,NUP107,GEMIN6,TNPO2,TNPO3,NUP153,GEMIN4,STAT3,NUP85,TGFB1,PPP3CA,SEC61B,NXT1,SNRPB,DDX20,HTATIP2,NUP155,NUTF2,PTTG1IP,GEMIN5,RAB18,KPNA1,KPNA4,ARNTL,PML,PPP3R1,NUP62,KPNA2,SNRPG,NUP58,IPO4,GEMIN7,NXT2 |
| 2.417e-07 | -15.24 | GSE22432_CDC_VS_COMMON_DC_PROGENITOR_DN | MSigDB lists | GSE22432_CDC_VS_COMMON_DC_PROGENITOR_DN | 184 | 55 | 17377 | 2626 |
H2AFZ,NOP2,RRP15,NDUFAF2,TMX4,MRPS26,UCK2,DHX9,KIF23,TOP2B,OAT,WDR5,FANCL,MRPL50,APLP2,RPN1,PA2G4,CCNA2,UTP18,ATIC,PRC1,SUCLG2,BCAP29,KNTC1,GLE1,OSTC,TOP1MT,SLC12A2,NUDC,PRPF19,SRSF10,FYTTD1,ADAM17,PRIM2,PBK,RAD51AP1,EMB,RRM2,NFATC2,ARHGDIB,GLO1,EIF3G,DTWD1,ANKRD10,NAP1L1,HSPBP1,ATAD2,SEC61A1,HINT1,LSM6,ELMO1,PPA2,RWDD4,SLC16A1,RRS1 |
| 2.417e-07 | -15.24 | GSE17721_LPS_VS_POLYIC_16H_BMDC_UP | MSigDB lists | GSE17721_LPS_VS_POLYIC_16H_BMDC_UP | 184 | 55 | 17377 | 2626 |
MMACHC,NDUFV2,ST13,SEC61G,SRGN,UROD,BABAM1,HEXB,UCK2,NDUFA4,ADPGK,LANCL1,STMN1,SPPL2A,MCTS1,UBXN2A,MLX,ATP2A2,PPP6C,PTPN11,ANP32A,UPF2,PRADC1,FBL,STRAP,RNF5,MYO5A,SRSF10,TDP1,CCT2,EIF3L,RNASEH2C,FOPNL,BTG2,METTL5,TUFM,TUBGCP5,WDHD1,GLO1,TANC1,MRPS14,LSG1,ECH1,PON2,CDC16,RAD18,ACOX1,LRPPRC,GLG1,COPS6,ZNF830,IGBP1,RTN3,CHID1,IPO4 |
| 2.417e-07 | -15.24 | GSE41867_NAIVE_VS_EFFECTOR_CD8_TCELL_DN | MSigDB lists | GSE41867_NAIVE_VS_EFFECTOR_CD8_TCELL_DN | 184 | 55 | 17377 | 2626 |
INTS2,BCCIP,GCLM,IMMT,TP53RK,HNRNPAB,MTX3,MRPS2,DHPS,URB2,CHD1L,C19orf48,SLC20A1,POFUT1,SNAPC4,LRRC14,ANKRD26,PA2G4,CLUAP1,NOL11,NT5DC1,COPS7B,ECD,PTGES3,LDLRAD3,HDHD2,CAMK2G,TELO2,CCT2,CYFIP1,NTPCR,TCTEX1D2,FAM49B,NOL8,TEX10,C1orf35,WDHD1,ELP4,DNAJA1,METTL22,LUC7L,CHCHD6,SF3A2,SNRPA,C1orf122,DTWD1,KPNA4,KPNA1,MRPL55,CORO1C,LRPPRC,E2F1,SMPD4,PDCD11,SLC25A39 |
| 2.417e-07 | -15.24 | GSE9988_ANTI_TREM1_VS_CTRL_TREATED_MONOCYTES_DN | MSigDB lists | GSE9988_ANTI_TREM1_VS_CTRL_TREATED_MONOCYTES_DN | 184 | 55 | 17377 | 2626 |
RHOG,KIF3B,HECA,PHF23,RPS6KA1,CCM2,KLF13,CTCF,CREBL2,CDIPT,TWF2,MAPK14,RCOR3,GNB2,GIT2,KIAA1147,PIP5K1C,PAIP2,MAT2B,PHC2,RAB8A,FAM89B,GLTP,MAVS,GLE1,MAP3K14,MAML1,ZNF710,TNRC18,FRMD8,CTDSP2,KDM3B,AMPD2,ORAI2,TRIM8,FOXK1,TACC1,MAP7D1,USP22,ARID1A,PTTG1IP,SMAP2,DDX17,MYO1F,TFEB,CSK,DHX16,ACOX1,STK38,RNF38,ZDHHC7,CAB39,NUP62,WIPI2,DCAF5 |
| 2.417e-07 | -15.24 | GSE25123_CTRL_VS_IL4_STIM_MACROPHAGE_DN | MSigDB lists | GSE25123_CTRL_VS_IL4_STIM_MACROPHAGE_DN | 184 | 55 | 17377 | 2626 |
ZNF296,KARS,ASH1L,RPS2,CYLD,RPLP2,SESTD1,SCYL1,MCCC1,COX4I1,SNN,SLC20A1,CMTM6,COPG2,LMNA,C2orf68,CSDE1,DST,RAB21,UBE2Q2,PTEN,ATIC,H2AFY,TTC4,CENPM,FBL,PIKFYVE,ARID4A,IMPA2,MICAL3,PAQR6,PPP3CA,TIMP2,FOXK1,KAT2A,TSPYL4,MIER2,PRMT2,RPS9,RPSA,EIF3H,TWISTNB,RPL36,MAP3K4,TAB2,EIF2D,PTAR1,OGT,ADAM9,USP20,CABIN1,MBOAT1,RBPJ,LTA4H,TRAF5 |
| 2.417e-07 | -15.24 | GSE36527_CD69_NEG_VS_POS_TREG_CD62L_LOS_KLRG1_NEG_DN | MSigDB lists | GSE36527_CD69_NEG_VS_POS_TREG_CD62L_LOS_KLRG1_NEG_DN | 184 | 55 | 17377 | 2626 |
WASF2,RHOG,PRKAB1,DCAF15,FAM207A,PHF23,MRI1,EIF3D,MCCC1,UCK1,CHKB,SLC29A1,MAN2B1,DNAJB1,CDK11B,SLC20A1,PITHD1,REPS1,GNB2,PABPC4,FBXO22,PPP6C,FAM89B,ATP6V0A2,TAF5L,ATP6V0D1,CTDSP2,SPSB3,RNF5,MLST8,TMEM160,EIF3L,TMEM115,GUK1,TSTA3,BOLA1,UBE2V1,COMMD4,RHOT2,SERP1,SNRPA,RPA1,JAK1,STAT6,WDR4,PPM1G,BCL7C,NUP62,STK11,PDXK,WIPI2,AKNA,FBXL3,NAA60,RHEBL1 |
| 2.417e-07 | -15.24 | GSE27786_LIN_NEG_VS_CD4_TCELL_UP | MSigDB lists | GSE27786_LIN_NEG_VS_CD4_TCELL_UP | 184 | 55 | 17377 | 2626 |
TMEM106C,BCL2L12,NDUFS1,MRPL42,TM9SF4,C1orf112,DBF4,OLA1,ZFYVE21,ABCB10,OAT,PNO1,LMNA,TMEM69,FARSA,ANKLE1,SUV39H2,ZDHHC13,YBX1,FNIP2,MRPL48,PRADC1,TFG,TTLL12,LRRC59,PTPRK,TDP1,TIMM8B,NTPCR,SGCE,PSPC1,MRS2,PPIE,NSUN2,ACSL3,PCGF6,SLC25A22,CCNF,CLNS1A,HSPBP1,PALB2,SCAP,RBL1,DBI,SMPD4,DMWD,NR2F2,CDK2,CCNB2,CD81,HRAS,GCSH,IPO4,SSSCA1,PTOV1 |
| 2.420e-07 | -15.23 | FOXM1 (forkhead box M1) | protein interactions | 2305 | 72 | 30 | 17029 | 2761 |
SART1,LARS,SNRNP200,DEPDC1,DHX29,CENPF,MYBL2,DNAJC9,BMS1,SMC2,CCNB1,UBE2I,USP5,LIN9,RB1,KIF18A,IARS,CDC27,RBMX,AXIN1,QARS,PRC1,ACAT1,KIF22,CDC25B,CHEK2,CDK2,STAT3,TERF1,DDX52 |
| 2.420e-07 | -15.23 | EEF1B2 (eukaryotic translation elongation factor 1 beta 2) | protein interactions | 1933 | 72 | 30 | 17029 | 2761 |
RPS2,CYLD,EWSR1,STRIP1,HARS,VHL,WBP2,STRN4,CUL3,CUL1,CSNK2A1,BRCA1,DNAJA1,ADRB2,UBQLN2,MCM2,SDHA,APP,SNRPA,CAND1,GTF2F1,AHNAK,HUWE1,AKAP8,H2AFX,UQCRH,NUP153,PLOD3,SMURF1,EEF1D |
| 2.445e-07 | -15.22 | ZHANG_RESPONSE_TO_CANTHARIDIN_DN | MSigDB lists | ZHANG_RESPONSE_TO_CANTHARIDIN_DN | 65 | 27 | 17377 | 2626 |
RPL29,ABCA3,NDUFB6,RHOC,IDH3A,TKT,RRM1,RPL15,RRM2,COX4I1,GTF3A,SNRPA,RPSA,PRIM1,SUPT16H,FARSA,PA2G4,TIMM23,RPS14,ZNF200,UQCRH,RUVBL2,PGAM1,MRPL3,MSH6,EEF1D,SSSCA1 |
| 2.468e-07 | -15.21 | GO_NUCLEAR_IMPORT | MSigDB lists | GO_NUCLEAR_IMPORT | 126 | 42 | 17377 | 2626 |
POLA2,NUP188,TSC2,PHB2,RAE1,NUP54,SNRPD3,RPAIN,NUP205,LMNA,SNUPN,NUP107,GEMIN6,TNPO2,TNPO3,NUP153,GEMIN4,F2R,STAT3,NUP85,TGFB1,PPP3CA,SEC61B,SNRPB,HTATIP2,DDX20,NUP155,NUTF2,PTTG1IP,MAPK3,GEMIN5,KPNA4,KPNA1,ARNTL,PML,NUP62,KPNA2,SNRPG,MAPK1,TOB1,IPO4,GEMIN7 |
| 2.481e-07 | -15.21 | WU_APOPTOSIS_BY_CDKN1A_VIA_TP53 | MSigDB lists | WU_APOPTOSIS_BY_CDKN1A_VIA_TP53 | 54 | 24 | 17377 | 2626 |
ZNF84,ASPM,PBK,TPX2,MKI67,RRM1,WDHD1,RACGAP1,AURKB,SMC2,MCM2,ANLN,CCNB1,NCAPG,BIRC2,FANCI,HNRNPA2B1,ATAD2,CEP55,PRC1,HMGB2,KNTC1,CDC25B,UBE2C |
| 2.487e-07 | -15.21 | PDIA3 (protein disulfide isomerase family A member 3) | protein interactions | 2923 | 143 | 48 | 17029 | 2761 |
BCCIP,ZNF207,PPIB,UNK,AGRN,ADAM10,SUZ12,SLC2A1,TAP1,NANS,PLXNA1,SND1,ITGB5,SDHA,APP,HLA-A,PA2G4,MDM2,PPME1,RAD23B,TXLNA,ANXA5,RPN2,TARDBP,TAGLN2,ATF2,STAT3,MTPN,ADAM17,ERO1A,MRPL12,LDHA,MCM2,RAB1A,DDX17,ADSS,HLA-B,PLAA,SEC61A1,CORO1C,KBTBD7,ITGB1,FUS,GPI,CLU,RBBP4,CDK2,NMD3 |
| 2.487e-07 | -15.21 | UQCRC2 (ubiquinol-cytochrome c reductase core protein 2) | protein interactions | 7385 | 143 | 48 | 17029 | 2761 |
COX15,NDUFS1,PRKCSH,TCF3,NDUFA4,COX4I1,ATP5F1B,ATP5PF,SDHA,NDUFS4,SSR1,RPN1,RAP1A,CDC42,HUWE1,ZNF746,ZNF326,HADHB,NDUFS8,RPN2,TECR,LMAN1,ATF2,HNRNPM,IDH3A,TUFM,VDAC2,SSR2,NFATC2,ADRB2,SRSF5,VDAC1,RAB1A,RAB5B,CCT8,RPSA,SDHB,KPNA4,IDE,ATP1A1,SEC61A1,DDOST,UQCRH,ACADM,ATP5F1A,CLN3,EHD4,PSMC1 |
| 2.489e-07 | -15.21 | TUFM (Tu translation elongation factor, mitochondrial) | protein interactions | 7284 | 177 | 56 | 17029 | 2761 |
RPS2,CYLD,PPP1R2,PHB2,SUZ12,UBXN1,HEXB,MCCC1,MYH9,RPL15,NENF,ARF1,BECN1,GFM2,RPL11,RPL23A,CAPN2,RPN1,PTEN,RPL17,HUWE1,BANF1,ZNF746,ARL6IP1,NSFL1C,RPL19,CRY2,LMAN1,MRPL11,PTPRK,COA3,EXOSC6,RPL6,CUL3,RPL8,MRPS10,RPS24,NFATC2,ADRB2,MCM2,MRPS14,RAB5B,MRPL2,PLAA,RPL32,DDOST,IARS2,FUS,CLU,PPP5C,CDK2,CHMP7,SMURF1,CD81,RPS26,MRPL3 |
| 2.498e-07 | -15.20 | ENO2 (enolase 2) | protein interactions | 2026 | 87 | 34 | 17029 | 2761 |
PPIB,NAT9,TXN,POC1A,SUMO2,HABP4,TKT,ENSA,CUL1,FKBP2,NDUFS7,FKBP1A,SNUPN,PTEN,CENPJ,DUT,AKR1B1,TAGLN2,GPX4,WDR1,CUL3,EZR,RAB1A,CAND1,SEC31A,HINT1,MAP4,ST3GAL2,UBE2C,PGAM1,CDK2,POT1,TERF1,ANXA11 |
| 2.504e-07 | -15.20 | DNA Replication | REACTOME pathways | R-HSA-69306 | 109 | 40 | 10287 | 1696 |
POLA2,MCM10,CDT1,DBF4,ORC1,PSMD9,RPA2,RB1,PSMD2,PCNA,PSMD1,PSMA6,CCNA2,MCM5,CDKN1B,ORC3,GINS1,RFC3,PRIM2,PSMA8,PSMB7,E2F3,PSMA1,CDC6,MCM2,PSMB9,RFC2,PSMB3,GINS4,PRIM1,RPA1,PSMC4,POLE,RPS27A,PSMD3,PSMD8,E2F1,CDK2,E2F2,PSMC1 |
| 2.516e-07 | -15.20 | RTF1 (RTF1 homolog, Paf1/RNA polymerase II complex component) | protein interactions | 23168 | 38 | 20 | 17029 | 2761 |
DNMT3A,BRD4,CSNK2A1,CHD1,CDC73,PIP4K2A,APP,SUPT16H,RPL37,PAF1,UBTF,STAT1,HADHB,PTPN11,CTR9,TCEA1,ARRB2,CD81,SSRP1,SRPK2 |
| 2.518e-07 | -15.19 | CAT (catalase) | protein interactions | 847 | 51 | 24 | 17029 | 2761 |
ATP5IF1,CYLD,MECP2,UFC1,ACTR3,LDHA,SMARCA4,CYCS,MCM2,APP,PRDX1,BCAT2,ABL2,GNAS,CAT,KEAP1,PEX5,ACOX1,PRDX5,PPA2,PTPN11,USP53,CFL1,LDHB |
| 2.539e-07 | -15.19 | GO_CHROMATIN | MSigDB lists | GO_CHROMATIN | 421 | 103 | 17377 | 2626 |
MBD1,TCF12,DNMT3A,H2AFZ,MPHOSPH8,KDM4A,UBR2,SUZ12,MAGED1,CSNK2A1,SMARCA4,SIRT2,INO80E,PARK7,MXD1,MBD4,PHC2,SAP130,OIP5,AHCTF1,UCHL5,PDS5B,KIF22,TARDBP,SMARCE1,DNMT1,HTRA2,PLK1,HMGN4,BAZ2A,GABPA,WBP2,WDR82,MCM2,H2AFV,MBD3,TRIM28,ASF1B,CHAF1A,BRMS1,SMAD2,STAT6,E2F4,STAT1,H2AFX,UHRF2,OGT,BAZ1B,ACTB,ANP32E,BEND3,NCOA1,H3F3A,SMAD4,HDAC2,NCOR2,SHPRH,MECP2,TCF3,CENPF,MEF2A,TOP2B,HMGN3,CAPN2,RPA2,IRF4,RB1,SMC3,SUV39H2,MBD2,BUD31,TIMELESS,H2AFY,CTR9,CREB1,CITED2,TNRC18,STAT3,MSH6,HP1BP3,HMGN1,NASP,ETV3,KAT2A,HMGN5,MTA2,LDB1,POLR3GL,ARID1A,MEN1,HMGN2,CBX3,UPF1,SETD3,RBMX,CDCA5,E2F1,HMGB2,RUVBL2,YY1,RBBP4,IPO4,CDKN2A |
| 2.549e-07 | -15.18 | BLUM_RESPONSE_TO_SALIRASIB_UP | MSigDB lists | BLUM_RESPONSE_TO_SALIRASIB_UP | 236 | 66 | 17377 | 2626 |
COPA,XIAP,RRAGC,BCL2L1,EIF1B,MAP1LC3B,KCMF1,BIRC2,RAD23A,NAPG,DUS4L,IARS,SIAH1,AP3S2,TCEA1,TP53BP2,EIF5,FAM3A,BAK1,ERCC1,PPIE,AZI2,RAB22A,SERP1,ARF4,EIF3H,DAP3,PSMD8,SEL1L,OGT,ATF6,CBX4,SEPHS2,UBXN1,CHIC2,CDK13,TMED3,PSEN1,CSNK1A1,FOXO3,DNAJB9,C12orf10,EIF2S2,BUD31,FEM1B,ARHGEF2,MYO5A,IFRD1,TNFAIP3,ELL2,DCTD,TARS,ECH1,YIF1A,EPRS,MTHFD2,GOLGA4,KPNA4,CSNK1G1,COX7A2L,MAPK6,SIAH2,CEBPG,GLG1,PPP1R11,RNF14 |
| 2.566e-07 | -15.18 | GO_REGULATION_OF_SIGNAL_TRANSDUCTION_BY_P53_CLASS_MEDIATOR | MSigDB lists | GO_REGULATION_OF_SIGNAL_TRANSDUCTION_BY_P53_CLASS_MEDIATOR | 157 | 49 | 17377 | 2626 |
MIF,BCL2L12,PRKAB1,TP53RK,PRKAA1,RMI2,TPX2,CSNK2A1,BLM,MAPK14,RMI1,MEAF6,JMY,CDK5,RPA2,RRN3,MDM2,PIN1,NOC2L,BRD7,TP53BP2,PLK3,RFC3,MTA2,EHMT1,TOP3A,RFFL,AURKB,BRCA1,PTTG1IP,RFC2,MBD3,RPA1,SUPT16H,TAF2,CHD3,RPS27A,HIPK2,PML,DDX5,STK11,TAF12,CHEK2,RBBP4,CDK2,TAF6,HDAC2,CDKN2A,SSRP1 |
| 2.572e-07 | -15.17 | SRRM1 (serine and arginine repetitive matrix 1) | protein interactions | 10250 | 160 | 52 | 17029 | 2761 |
NIFK,EWSR1,SRSF6,RBM8A,CSNK2A1,TOP2B,SNRPD3,LMNA,CNOT3,GTF2F1,SF3B2,RBM23,DNAJC8,SMC3,EIF4A3,PIN1,RBM34,SRSF4,EFTUD2,ABI1,HNRNPM,SRPK2,PRPF19,CDC5L,SNRNP200,SNRPB,ZMYND11,RNPS1,CUL3,BCLAF1,PRPF3,DNAJA1,SRSF5,OGFR,LUC7L,SF3A2,DHX15,EIF3H,CAND1,SUPT16H,CBX3,PAF1,RBM25,DHX16,SAFB,RBMX,DDX5,FUS,SRSF3,NKAPD1,IFI16,FUBP1 |
| 2.586e-07 | -15.17 | SLC25A3 (solute carrier family 25 member 3) | protein interactions | 5250 | 139 | 47 | 17029 | 2761 |
UNK,COX15,NDUFV2,MRPL9,TOMM20,CYLD,NDUFS1,MRPS26,NDUFA4,SDHA,QSOX2,MRPL50,RPN1,PTEN,HUWE1,ZNF746,ATP6V0A2,NDUFS8,CYC1,TECR,MTX2,IDH3A,RAB7A,SUGP2,CUL3,TUFM,ATP6V0A1,ADRB2,TOMM40,VDAC1,MCM2,RAB1A,PDHX,STOML2,CAND1,SDHB,MRPL2,SMAD2,ATP1A1,DDOST,TONSL,ACADM,FUS,CLN3,CDK2,SMURF1,MRPL13 |
| 2.587e-07 | -15.17 | TERF1 (telomeric repeat binding factor 1) | protein interactions | 7013 | 313 | 86 | 17029 | 2761 |
SRM,FOXM1,TRIP10,MYH9,SEC16A,CPNE3,PABPC4,TERF2IP,DST,DLG5,PA2G4,SP100,SH3BP1,TNPO2,TALDO1,CFL1,RLIM,CDC37,NOL12,HMGN4,IDH3A,CDC6,BRCA1,MCM2,OGFR,DPYSL3,TAF2,PPP2CA,HSPA4,CLK3,PPM1G,MAP4,WDR4,KPNA2,KLHDC4,RTN3,POT1,PFKP,HSPH1,RPS2,MAPRE1,SRSF6,CENPF,TKT,CDK13,HMGN3,DNAJB1,HDGFL2,BLM,EPHX2,NEXMIF,LYAR,ANXA5,AHCY,RPL19,LRSAM1,UBE2M,EEF1D,TERF2,RBM15B,SPTAN1,LDHB,RPAP3,AMPD2,CYFIP1,DDX24,PRKDC,LDHA,C1orf35,PKM,DDX39A,PRDX1,DDX23,XRCC5,FBXO21,NAP1L1,KEAP1,ZHX1,ACLY,TBPL1,DNPH1,MDH1,YY1,BRWD3,TERF1,DDB1 |
| 2.605e-07 | -15.16 | GSE17721_POLYIC_VS_GARDIQUIMOD_24H_BMDC_DN | MSigDB lists | GSE17721_POLYIC_VS_GARDIQUIMOD_24H_BMDC_DN | 189 | 56 | 17377 | 2626 |
UBE2D3,RAB14,DNAJC2,MMACHC,PIGM,THOC1,IVNS1ABP,CXXC1,DAP,CHD1L,C16orf87,MOGS,ZFYVE21,MEF2A,PPP3CB,CDC42SE2,CHAC2,OAT,TMEM165,PABPC4,SSR1,CSDE1,ATP6V0B,CCNA2,SHC1,NOL11,UTP18,PPME1,BTF3L4,YBX1,NUP153,ECD,LMAN1,MRPL11,EIF5,LPCAT1,SLC35A1,FTSJ3,MOB4,EIF5A,FAM49B,HELB,MTA2,NSUN2,TUFM,ARHGEF12,MCM2,EIF4G2,ADSS,PPP2CA,WAS,ATP1A1,SEC61A1,LIMK1,ADAM9,CHID1 |
| 2.605e-07 | -15.16 | GSE5503_PLN_DC_VS_SPLEEN_DC_ACTIVATED_ALLOGENIC_TCELL_DN | MSigDB lists | GSE5503_PLN_DC_VS_SPLEEN_DC_ACTIVATED_ALLOGENIC_TCELL_DN | 189 | 56 | 17377 | 2626 |
DDX58,RHOG,HSPH1,SART1,PKP4,CASP6,PHF23,MDH2,RAF1,ENSA,CSNK2A1,B4GALT1,AGPAT3,SIKE1,CREBL2,EZH1,MIEN1,BIRC2,CMTM6,ANKRD39,TMEM179B,SEC11A,DNAJC8,MTMR4,PPP1R12C,AQR,MAML1,ABI1,SMC4,TMEM160,ADCY7,GCC2,TRIM8,TIMP2,DENND4C,NUDT4,SELPLG,MTMR6,LRRC8A,KRAS,NDRG3,C1orf122,CAT,KPNA4,WAS,OSBPL11,PPP2R5A,CSNK1G1,AXIN1,ARNTL,WDR7,TSTD2,NRBP1,CHID1,CAPN1,RNF114 |
| 2.607e-07 | -15.16 | HSPA5 (heat shock protein family A (Hsp70) member 5) | protein interactions | 3309 | 482 | 121 | 17029 | 2761 |
RAB14,SART1,CYLD,TXN,HNRNPAB,PRKCSH,RAF1,HNRNPUL2,MYH9,CUL1,STMN1,SSR1,PRNP,HNRNPA2B1,PSMD1,SHC1,UCHL5,TARDBP,AHCYL1,TFG,PDIA6,DNMT1,DVL2,CDC37,CDC5L,CDKN2AIP,UBQLN4,SEPT9,NCK1,VHL,RAB7A,CUL3,HNRNPF,DNAJC9,NFATC2,AURKB,BRCA1,DNAJA1,IL12RB1,MCM2,RPSA,CLNS1A,STOML2,DNAJC10,PON2,AHNAK,HSPA4,TIMM13,SEC61A1,SURF4,HNRNPR,DGCR8,MAP4,CAMKMT,RPLP1,SEL1L,H2AFX,DNAJC17,ST3GAL2,ACTB,FUS,CLU,NCOA1,COPS6,ARRB2,SMURF1,PPIB,DNAJC2,HSPH1,NCOR2,EWSR1,MAPRE1,TOR3A,UBXN1,DHX9,PCSK7,PAWR,DNAJB1,B4GALT4,RAB11A,CDC73,TUBGCP2,HAUS2,DNAJB9,WWP2,RPA2,RPN1,SUB1,DNAJC8,MEX3C,HUWE1,AHSA1,YBX1,TAGLN2,SPTAN1,STAU1,TRAFD1,DDX24,PRKDC,ILF3,RPL8,SYVN1,ADRB2,SEPT7,METTL22,EIF4G2,RPA1,CAND1,MAGED2,HLA-B,NUCB1,HSPBP1,HNRNPH3,SIL1,NUP62,RUVBL2,ATP5F1A,YY1,SNRNP70,CDK2,HNRNPDL |
| 2.628e-07 | -15.15 | nuclear chromatin | cellular component | GO:0000790 | 356 | 89 | 18223 | 2701 |
TCF12,MAX,DNMT3A,H2AFZ,MPHOSPH8,SUZ12,CSNK2A1,SMARCA4,INO80E,SIRT2,MXD1,SAP130,USF1,KMT5C,UCHL5,TARDBP,MCMBP,SMARCE1,GABPA,RAD51AP1,WBP2,NFATC2,PBRM1,MEF2D,MBD3,H2AFV,TRIM28,ASF1B,CHAF1A,BRMS1,SMAD2,CHD3,E2F4,STAT6,H2AFX,UHRF2,STAT1,ANP32E,ACTB,NCOA1,BEND3,H3F3A,SINHCAF,SMAD4,HDAC2,NCOR2,TCF3,DHX9,MEF2A,PAWR,ASXL2,ARID1B,YY1AP1,RB1,IRF4,MBD2,BUD31,TIMELESS,H2AFY,SS18L1,CITED2,CREB1,STAT3,MSH6,PHF10,TELO2,KAT2A,NASP,ETV3,MTA2,LDB1,POLR3GL,ARID1A,MEN1,APPL1,CBX3,NSMF,SETD3,RBMX,CDCA5,APPL2,E2F1,HMGB2,RUVBL2,CENPT,YY1,RBBP4,IPO4,SMARCD1 |
| 2.639e-07 | -15.15 | mitochondrial respiratory chain | cellular component | GO:0005746 | 82 | 31 | 18223 | 2701 |
NDUFA5,COX15,NDUFV2,COX5B,NDUFS1,NDUFB6,UQCR10,DMAC2,NDUFA4,COX4I1,NDUFA7,NDUFB1,FOXRED1,SDHA,PARK7,NDUFS7,NDUFS4,SDHB,NDUFV1,NDUFA2,NDUFB4,NDUFA11,COX7A2L,COX8A,COX5A,NDUFB9,UQCRH,NDUFS8,CYC1,NDUFS5,NDUFA3 |
| 2.645e-07 | -15.15 | GNF2_NPM1 | MSigDB lists | GNF2_NPM1 | 69 | 28 | 17377 | 2626 |
DNAJC2,KARS,EIF3L,HMGN1,ST13,RPL6,GTPBP4,RPS24,SNRPD3,DDX39A,CCT8,DHX15,RPSA,CLNS1A,EIF3A,SRSF1,RPL37,HNRNPA2B1,NAP1L1,HSPA4,NOL11,RPL17,HNRNPR,RBMX,LRPPRC,TARDBP,BTF3,FBL |
| 2.645e-07 | -15.15 | PID_MTOR_4PATHWAY | MSigDB lists | PID_MTOR_4PATHWAY | 69 | 28 | 17377 | 2626 |
PDPK1,RHOA,NRAS,TSC2,RB1CC1,RPS6KA1,RAF1,RAC1,RRAGC,KRAS,CYCS,AKT1S1,MAP2K2,RHEB,MAPK3,EEF2K,RRN3,TSC1,PML,ATG13,YWHAZ,YY1,CDK2,MAPK1,YWHAH,HRAS,PDCD4,MLST8 |
| 2.658e-07 | -15.14 | CDKN2A (cyclin dependent kinase inhibitor 2A) | protein interactions | 1029 | 186 | 58 | 17029 | 2761 |
NCOR2,MCM10,TRIP12,GGA1,ZFP91,LAMTOR3,ARFIP2,SMARCA4,PTP4A3,NSD3,BCL2L1,NCKAP1,FKBP2,UBE2I,BECN1,TTF1,MIS12,RPL11,HNRNPA2B1,CDKN2C,PA2G4,MDM2,PCNA,ZNF420,PTEN,HUWE1,MCM5,SIVA1,CARF,CDC5L,CDKN2AIP,PPP1R9B,DEAF1,VHL,SNRPB,LSM8,RRM2,CDC6,UBE4B,BRCA1,MCM2,CDK11A,MTR,TRIM28,SNRPA,PDCD6,HSPA4,AHNAK,DGCR8,ACLY,PML,E2F1,PIAS2,ACTB,RUVBL2,YY1,TUBB,CDKN2A |
| 2.661e-07 | -15.14 | GO_MITOTIC_CELL_CYCLE_CHECKPOINT | MSigDB lists | GO_MITOTIC_CELL_CYCLE_CHECKPOINT | 135 | 44 | 17377 | 2626 |
ZNF207,CLSPN,CENPF,CSNK2A1,TOP2B,BCL2L1,BLM,CCNB1,MAD2L2,FANCI,CNOT3,RFWD3,RPA2,RB1,MDM2,PCNA,CCNA2,CENPJ,MSH2,GTSE1,CDKN1B,KNTC1,CNOT6L,ATF2,CARM1,PLK1,TGFB1,PLK3,BTG2,PRKDC,SOX4,RBM38,RPS27A,E2F4,TFDP1,PML,E2F1,CNOT6,CHEK2,TFDP2,ZNF830,CDK2,TERF1,HRAS |
| 2.676e-07 | -15.13 | EP300 (E1A binding protein p300) | protein interactions | 2033 | 507 | 126 | 17029 | 2761 |
TCF12,ZNF76,PTMS,IMMT,MAX,ATXN3,TRERF1,CXXC1,MAGED1,SUMO2,IRF3,SIRT2,CCNB1,UBE2I,MAPK14,RAD23A,HNRNPA2B1,USF1,MDM2,PCNA,CCNA2,PIN1,MTA1,FBXW2,ANAPC7,TP53BP2,ATF2,STRAP,CARM1,SP3,BRD4,BIRC3,GABPA,EID1,VHL,WDR82,NFATC2,AURKB,BRCA1,MEF2D,SOX4,MCM2,PDHX,DDX17,PPP2CA,BRMS1,CDC16,SMAD2,STAT6,HIPK2,WDR59,ARNTL,STAT1,KPNA2,ACTB,NCOA1,COPS6,H3F3A,SMAD1,MAPK1,RPS26,SMAD4,POU3F2,NCOR2,EWSR1,TCF3,CDT1,PRKAA1,KLF13,MEF2A,WDR5,ETS1,FOXO3,NEIL2,JMY,FBXO3,RB1,SUB1,KLF16,MCM5,XPA,NABP2,BRD7,YBX1,SS18L1,NAP1L4,CREB1,CITED2,MAML1,STAT3,N4BP2,NCOA2,MSH6,TERF2,HMGN1,KAT2A,DDX24,EMB,PRKDC,MYBL2,ILF3,ANAPC2,PKM,MPG,ELK1,IRF5,POLR2A,HMGN2,XRCC5,NAP1L1,GOLGA2,ETS2,GPS2,PML,E2F1,YWHAZ,DDX5,ZRANB2,RUVBL2,YY1,MAP3K5,NR2F2,CDK2,USF2,TERF1,DDB1 |
| 2.688e-07 | -15.13 | MAPKAPK2 (mitogen-activated protein kinase-activated protein kinase 2) | protein interactions | 9261 | 58 | 26 | 17029 | 2761 |
PLK1,TSC2,TCF3,AGO2,CUL3,BCL2L1,BECN1,MAPK14,PARN,TRIM28,MAPK3,EEF2K,PHC2,MDM2,SHC1,ARPC5,LIMK1,RCSD1,PIAS2,YWHAZ,DDX5,CDC25B,CREB1,STAT3,MAPK1,PABPC1 |
| 2.699e-07 | -15.13 | ELVIDGE_HIF1A_AND_HIF2A_TARGETS_UP | MSigDB lists | ELVIDGE_HIF1A_AND_HIF2A_TARGETS_UP | 37 | 19 | 17377 | 2626 |
SRM,RPP25,HSPH1,IDH3A,TOR3A,ABCF2,SLC29A1,SLC35B1,GYG1,SLC25A44,POLR3K,LSG1,CHKA,FLAD1,HSPA4,CCDC86,ATP6V0A2,CORO1A,RRS1 |
| 2.733e-07 | -15.11 | GO_VESICLE_MEDIATED_TRANSPORT | MSigDB lists | GO_VESICLE_MEDIATED_TRANSPORT | 1148 | 235 | 17377 | 2626 |
CCDC93,RAB14,TMED7,PDCD6IP,COPA,TSC2,AP3M2,TGOLN2,KIF2C,CDC42SE2,SEC16A,BECN1,RUFY1,SYNRG,CALM2,CDK5,NAPG,RAB8A,CDC42,AP3S2,DPYSL2,RAB35,PIK3R2,TXLNA,AP1M1,DNM2,AP2B1,KIF22,RP2,MARCH2,TFG,USO1,RHOBTB3,TMEM115,NCK1,KIF15,EZR,LRP5,MCFD2,STX16,RAB5B,RAB22A,RAB2B,ARF4,OPTN,NECAP2,TBC1D17,WAS,TMED10,LIMK1,MYO18A,ITGB1,ACTB,CLU,VPS4A,CLN3,ARRB2,RTN3,ANXA11,HSPH1,DNAJC5,GORASP1,GGA1,VAV2,NKD2,EPN1,KLC1,KIF23,RACGAP1,PPP3CB,TMED3,RAB6A,NCKAP1,PSEN1,COPG2,COPB2,CD59,VMP1,ARPC5,SNX18,RINL,RIMS3,KIFAP3,PIKFYVE,LRSAM1,PPP6R1,SYTL3,CSNK1G3,TMED2,KDELR1,PREB,CYFIP1,CYTH1,GCC2,TRAPPC9,MAPKAPK3,WDR1,EIF2AK1,ADRB2,CYFIP2,ARPC1A,GOSR1,PI4K2A,SEC31A,GOLGA4,GOLGA2,NSF,CSNK1G1,SNAP23,ERGIC3,EXOC4,PPP6R3,EHD4,UNC13C,NRBP1,EXOC3,WASF2,SNX27,CHMP2A,ANKRD27,CORO7,SYS1,RAB11B,TRIP10,DYNLL1,ACTR3,COPE,RAC1,ANK3,VTI1A,MON1B,MYH9,BCL2L1,AP1B1,LYN,CPNE3,BCAP31,APP,ANKRD28,VAV1,APLP2,BRPF3,SAR1A,TBC1D14,PPP6C,BCAP29,CORO1A,CYB5R1,LMAN1,CLTB,PDIA6,GCC1,ABI1,DCTN1,SNX8,CPNE1,PPT1,RAB7A,GOPC,CUL3,WIPF1,CHMP2B,RAB1A,AP4E1,ERC1,KIF2A,CHMP4A,SURF4,VPS26B,CORO1C,AP1S1,CHMP4B,SCARB1,MAPK1,AP2S1,LRP8,ABCA1,DYNC1LI2,CSNK1D,KIF3B,GOLPH3L,SCAMP3,SRGN,SCYL1,DCTN2,HABP4,VPS45,TMX3,CHIC2,JMJD6,ARF1,GGA2,AP3S1,CSNK1A1,RAB11A,SCYL2,TFRC,PIP5K1C,KLHL20,SEC24C,ARF5,LDLRAD3,GTF2H2,MICAL3,MYO5A,SPTAN1,TGFB1,CSNK1G2,SNX2,DENND1B,SCFD2,COG1,PACS1,RAB3IP,KIF11,MACF1,PICALM,MAPK3,YIF1A,SEC23IP,KIF18A,GOLGA7,ELMO1,SNAP29,FAM3C,STX18,USP20,LY75,PSAP,CHMP7,CD81,HRAS,VPS29,ESYT2,SNAPIN |
| 2.766e-07 | -15.10 | NUP50 (nucleoporin 50) | protein interactions | 10762 | 95 | 36 | 17029 | 2761 |
ARID2,CXXC1,PRKAA1,TOR1AIP1,APP,PAIP1,LMNA,KIFC1,PTPN2,KIF5B,NUP107,AP2B1,BRD7,CDKN1B,NUP153,NUP85,SRPK2,LDHB,PHF10,GMFB,CUL3,WDHD1,CDCA2,PBRM1,PLEC,KPNA4,EIF4ENIF1,KPNA1,HSPBP1,KIF18B,FBXO28,PFDN4,KHSRP,KPNA2,IFI16,SMARCD1 |
| 2.766e-07 | -15.10 | DDX39B (DExD-box helicase 39B) | protein interactions | 7919 | 95 | 36 | 17029 | 2761 |
CYLD,SARNP,THOC1,SUZ12,RAE1,RBM8A,STRN4,PABPC4,C12orf10,TFAP4,RPN1,AHSA1,DNM2,RPN2,RNASEH2A,TECR,ATF2,PABPC1,SRPK2,CDC5L,TXNL1,FYTTD1,MOB4,STAU1,SREK1,BCLAF1,EXOSC9,DDX39A,DDOST,ZHX1,HIPK2,PIAS2,ACADM,RBBP4,CDK2,SMAD4 |
| 2.782e-07 | -15.09 | TUBB (tubulin beta class I) | protein interactions | 203068 | 267 | 76 | 17029 | 2761 |
NPHP4,PDCD6IP,CYLD,ATXN3,DYNLL1,SUMO2,OLA1,CUL1,RUFY1,APP,VAV1,MDM2,SHC1,DPYSL2,ZNHIT6,PIK3R2,MICU2,TNPO2,TARDBP,EIF5,ATF2,HTRA2,CDC37,CDC5L,PLK1,FYTTD1,CCT2,SNRNP200,CUL3,LNX2,AURKB,BRCA1,MCM2,GFER,EML4,MAT2A,HSPA4,MAP4,UQCRH,FUS,COPS6,SMURF1,UNK,MAPRE1,PHB2,B4GALT1,CDK13,ATP5F1B,TUBGCP2,HAUS2,COPB2,MAT2B,RPA2,SMC3,PTEN,HUWE1,MCM5,ANXA5,YBX1,CSNK1G3,STAU1,KAT2A,ADRB2,PKM,CCT8,CAND1,RPA1,MAGED2,EPRS,HGS,PFDN4,YWHAZ,ASNA1,ECPAS,CD81,CDKN2A |
| 2.790e-07 | -15.09 | GOLDRATH_NAIVE_VS_EFF_CD8_TCELL_DN | MSigDB lists | GOLDRATH_NAIVE_VS_EFF_CD8_TCELL_DN | 194 | 57 | 17377 | 2626 |
UBL3,H2AFZ,TXN,MCM10,GNPDA1,CDCA3,RRM1,CDCA8,KIF2C,TCF19,STMN1,LYN,REEP5,RAB11A,KIFC1,CAPN2,DTL,CDKN2C,IRF4,PCNA,CCNA2,MCM5,PRC1,KIF22,MDFIC,TMEM14C,S100A6,TACC3,CYFIP1,MAPRE2,TK1,PRIM2,ELL2,ASPM,NUDT4,MKI67,EMP3,CDC6,NUSAP1,AURKB,BRCA1,CCNF,ANLN,KRTCAP2,ODC1,KIF11,ASF1B,CHAF1A,PRIM1,MYO1F,BIRC5,CDCA5,MAPK6,H2AFX,ITGB1,PGAM1,CCNB2 |
| 2.797e-07 | -15.09 | MALONEY_RESPONSE_TO_17AAG_DN | MSigDB lists | MALONEY_RESPONSE_TO_17AAG_DN | 73 | 29 | 17377 | 2626 |
PLK1,RPL35,HNRNPAB,POLR2L,DYNLL1,SNRPB,NACA,LDHA,RRM2,CYCS,RPL27A,ARF4,XRCC5,HNRNPA2B1,PA2G4,SUB1,IARS,TIMM23,PRDX3,RBMX,MDH1,KPNA2,SNRPG,PTGES3,SRSF3,CLTB,UBE2C,GM2A,HNRNPM |
| 2.832e-07 | -15.08 | ribonucleoside monophosphate metabolic process | biological process | GO:0009161 | 245 | 68 | 17256 | 2622 |
COX15,NDUFA5,NDUFB6,UQCR10,UCK2,OLA1,UCK1,ADPGK,ATP6V1B2,ATP5PF,SDHA,UPRT,NDUFB9,ATP6V0A1,OGDH,NDUFA7,NDUFB1,TAZ,STOML2,NDUFA11,COX5A,DHTKD1,UQCRH,NUDT11,PFKP,NDUFV2,COX5B,GALK1,NDUFS1,MECP2,NDUFA4,CYCS,COX4I1,ATP5F1B,NDUFS7,NDUFS4,GART,NDUFV1,NDUFA2,NDUFB4,ATIC,MSH2,ATP6V0A2,NDUFS8,CYC1,NDUFA3,TGFB1,AMPD2,GUK1,NUDT4,LDHA,ADSL,ATP5MF,PKM,HSPA1B,ADSS,ATP5MC3,PARG,PRPS2,COX7A2L,COX8A,IMPDH1,ATP5F1A,GPI,NDUFS5,PGAM1,NIPSNAP2,NUDT3 |
| 2.853e-07 | -15.07 | GSE14000_TRANSLATED_RNA_VS_MRNA_DC_DN | MSigDB lists | GSE14000_TRANSLATED_RNA_VS_MRNA_DC_DN | 162 | 50 | 17377 | 2626 |
SYS1,TRAF7,RWDD1,RPLP2,DAP,ZFYVE21,GTF3A,SDF2L1,PABPC4,ANKRD39,RPL11,RPL23A,C2orf68,RPL17,POP7,BRI3,YBX1,RPL19,CPSF4,ARL5A,PABPC1,EEF1D,GPX4,ORAI2,DEAF1,EIF3L,PTPN18,RPL35,GUK1,VHL,RPS10,JTB,RPL8,TMEM147,PRMT2,ARPC1A,SERP1,RPSA,RPL36,RPL32,DUSP3,RPS14,QARS,RPLP1,TBPL1,BCL7C,TMEM219,SSNA1,IGBP1,ZNF511 |
| 2.859e-07 | -15.07 | S100A9 (S100 calcium binding protein A9) | protein interactions | 6280 | 99 | 37 | 17029 | 2761 |
ZNF207,UNK,SART1,CYLD,EWSR1,TOP2B,THRAP3,MAPK14,SRRT,SHC1,CDC42,EIF4A3,PTEN,MCM5,ZNF326,TRA2B,SRSF10,SRSF11,PSRC1,SF3B6,RNPS1,PSMB7,TOPORS,SRSF5,MCM2,MATR3,DHX15,SUPT16H,SURF4,LUC7L3,SRSF3,ARRB2,SINHCAF,USF2,SSSCA1,TUBB,SSRP1 |
| 2.869e-07 | -15.06 | organonitrogen compound catabolic process | biological process | GO:1901565 | 1001 | 210 | 17256 | 2622 |
ADA2,PDCD6IP,AGRN,HEXB,MCCC1,CUL1,UBE2Z,GLUD1,NHLRC3,SIRT2,UBQLN2,CCNB1,UBE2I,USP48,OAT,BIRC2,RNF103,FBXO22,BCAT2,MBD4,PCYOX1L,TET3,PSMD1,GOT2,SLC44A1,RAD23B,AP2B1,OGG1,PCBP2,USP34,PLK1,RBX1,TOPORS,USP22,AURKB,CCNF,USP21,RPS27A,PSMD8,AXIN1,NAGLU,ATE1,ARRDC1,CHEK2,CLU,VPS4A,KLHL42,FBXL3,CLN3,ARRB2,NGLY1,NUDT11,PSMC1,LONP2,UBE2D3,RMND5A,TMUB1,DHPS,UBXN1,ADO,SDC2,KCTD17,PM20D2,ZNRF3,PSMD9,VPS25,RHBDD1,NPLOC4,GNS,DTL,PDXP,RNF121,ZNRF2,FBXO7,FBXL7,AHCY,ACAD8,ZRANB1,LRSAM1,CPQ,ERLIN1,NUDT4,MAN1B1,GBA,USP10,PSMA1,UBE4B,SYVN1,ARMC8,PSMB3,ISG15,PSMC4,DERL1,CDC27,KLHL15,SIAH2,DCAF11,USP32,CTSA,DNPH1,SMPD4,ECPAS,HEXA,RNF139,NUDT3,USP7,ATXN3,CYLD,UBR2,PTTG1,RAD23A,USP5,UBXN2A,PSMA6,MDM2,SIAH1,MTA1,DUT,UCHL5,KIF14,SOCS6,NSFL1C,ANAPC7,TTC3,CLN6,GM2A,SPSB3,HTRA2,RLIM,CHP1,PRPF19,ENPP4,SEC61B,PPT1,PSMA8,HPDL,RAB7A,PSMB7,CUL3,OGDH,CDC23,EDEM2,PSMB9,TOLLIP,USP36,BTBD1,ANKZF1,DNAJC10,IDE,CDC16,HINT1,UBXN2B,PSMD3,ARNTL,RNF38,SEL1L,CHMP4B,TRIM32,USP11,SMURF1,LTA4H,AP2S1,CHID1,USP13,TRIP12,MANBA,SDF2L1,CHAC2,UBE4A,CSNK1A1,DNAJB9,NEIL2,WWP2,CAPN2,PSMD2,CTSS,KLHL20,GTSE1,LTN1,FBXL19,RNF5,LYPLA2,TGFB1,TNFAIP3,GALC,USP42,RFFL,FBXO9,ANAPC2,WDR81,PNPLA8,PDE3B,NEU1,CTSL,FBXO21,SGSH,KEAP1,PLAA,CTBS,PML,ACAT1,USP20,PPP1R11,WDR91,UBE2C,SAT2,ANAPC4,DDB1,GCSH,FAF1 |
| 2.876e-07 | -15.06 | RRM | prosite domains | PS50102 | 211 | 57 | 12060 | 1670 |
NIFK,EWSR1,HNRNPAB,SRSF6,RBM8A,TIA1,SAFB2,MYEF2,RBM4,PABPC4,RAVER2,HNRNPA2B1,RBM23,RBM34,GRSF1,SRSF4,TRA2B,TARDBP,RBM3,RBM12B,RBM15,PABPC1,HNRNPM,SRSF10,RBM15B,SRSF11,RBM42,PSPC1,NOL8,SF3B6,PPIE,HNRNPF,RNPS1,CIRBP,SREK1,SRSF5,EIF4H,EIF3G,SLTM,MATR3,SNRPA,RBM38,SRSF1,RBM25,RBM47,SYNCRIP,HNRNPR,HNRNPH3,SAFB,RBMX,U2SURP,RBMS1,SRSF3,FUS,SNRNP70,HNRNPDL,CPEB2 |
| 2.901e-07 | -15.05 | GO_OXIDATIVE_PHOSPHORYLATION | MSigDB lists | GO_OXIDATIVE_PHOSPHORYLATION | 77 | 30 | 17377 | 2626 |
COX5B,NDUFA5,COX15,NDUFV2,NDUFS1,NDUFB6,UQCR10,MECP2,NDUFA4,COX4I1,CYCS,NDUFA7,NDUFB1,TAZ,NDUFS7,NDUFS4,NDUFV1,NDUFA2,NDUFB4,NDUFA11,COX7A2L,MSH2,COX8A,COX5A,NDUFB9,UQCRH,NDUFS8,NDUFS5,CYC1,NDUFA3 |
| 2.940e-07 | -15.04 | GSE3982_MAST_CELL_VS_TH2_DN | MSigDB lists | GSE3982_MAST_CELL_VS_TH2_DN | 185 | 55 | 17377 | 2626 |
MIF,ZNF207,PTMS,NUP188,C19orf53,MRPL42,PPP1R2,FOXM1,MRPS2,MRPS15,XAB2,ARFIP2,USP39,THRAP3,BLM,MYL6B,PNO1,SPAG5,CFLAR,EBP,PA2G4,FUT8,GMEB1,MSH2,TIMELESS,MRPL11,CLN6,NUP85,SMC4,HP1BP3,SLC39A9,SRSF11,PLK1,TDP1,ERF,MAPKAPK3,POLR2D,ELP4,EXOSC9,TOMM40,BORA,FADD,RPA1,FBXO21,SGSH,ATAD2,BIRC5,PRDX3,GOLGA8A,PTPN7,QRSL1,FKBP5,PIEZO1,PPP6R2,SSRP1 |
| 2.940e-07 | -15.04 | GSE2770_IL12_VS_TGFB_AND_IL12_TREATED_ACT_CD4_TCELL_6H_DN | MSigDB lists | GSE2770_IL12_VS_TGFB_AND_IL12_TREATED_ACT_CD4_TCELL_6H_DN | 185 | 55 | 17377 | 2626 |
DDX58,IMMT,RPS2,NDUFS1,PLXNC1,COPA,TMBIM4,TOR1AIP1,OLA1,CDK13,MAPK14,ZNF696,RPL23A,CALM2,VAV1,CLUAP1,CD3EAP,CAPZA1,TRA2B,CGGBP1,FDFT1,LDHB,WDR41,TRAPPC9,AATF,GALC,DENND1B,LDHA,USP10,BCLAF1,DNAJA1,ARID1A,FXR1,STX16,CBFB,ARMC8,RPS9,EIF3G,RHBDF2,BTBD1,ABHD5,NAP1L1,EIF4ENIF1,PPP2R5A,WDR11,TBL3,PQBP1,COX8A,TAF12,YY1,RPS26,HIPK3,DYNC1LI2,ADNP2,ZBTB24 |
| 2.940e-07 | -15.04 | GSE1432_6H_VS_24H_IFNG_MICROGLIA_DN | MSigDB lists | GSE1432_6H_VS_24H_IFNG_MICROGLIA_DN | 185 | 55 | 17377 | 2626 |
COX15,SNX27,COX5B,CDC40,CKLF,HLA-E,UBR2,MDH2,UQCR10,CDK2AP2,VPS45,UCK2,SLC25A12,BTN3A1,SDF2L1,ASXL2,PARN,FAM8A1,FBXO5,GNS,CDK5,DUS4L,LRRC8D,UCHL5,ATIC,MRPL34,CTR9,ECD,MVP,OGG1,DNMT1,LDHB,NIPSNAP1,CLCN3,ATP13A1,MLEC,ACP2,FAM172A,TYW1,METTL5,GALNT7,UBE4B,RHOT1,ASB13,PSMB9,FKBP3,CLNS1A,PCM1,TTC13,SEL1L,PPA2,ACAT1,LY75,ZMAT3,PFKP |
| 2.947e-07 | -15.04 | RRM | smart domains | SM00360 | 204 | 57 | 9493 | 1367 |
NIFK,EWSR1,HNRNPAB,SRSF6,RBM8A,TIA1,SAFB2,MYEF2,RBM4,PABPC4,RAVER2,HNRNPA2B1,RBM23,RBM34,GRSF1,SRSF4,TRA2B,TARDBP,RBM3,RBM12B,RBM15,PABPC1,HNRNPM,SRSF10,RBM15B,SRSF11,RBM42,PSPC1,NOL8,SF3B6,PPIE,HNRNPF,RNPS1,CIRBP,SREK1,SRSF5,EIF4H,EIF3G,SLTM,MATR3,SNRPA,RBM38,SRSF1,RBM25,RBM47,SYNCRIP,HNRNPR,HNRNPH3,SAFB,RBMX,U2SURP,RBMS1,SRSF3,FUS,SNRNP70,HNRNPDL,CPEB2 |
| 2.962e-07 | -15.03 | UTP14A (UTP14A, small subunit processome component) | protein interactions | 10813 | 107 | 39 | 17029 | 2761 |
NOP2,TRMT6,GADD45G,DHX9,CSNK2A1,APP,RGS1,PNO1,SSR1,RPA2,DDX56,PTEN,BUD31,RPF2,TP53BP2,FTSJ3,SRSF10,HP1BP3,CDC5L,PRPF19,SRSF11,PHF10,WDR18,SF3B6,VDAC2,GTPBP4,RABIF,SRSF5,SEPT7,MATR3,SRSF1,RBM25,SAFB,AXIN1,HNRNPH3,SRSF3,TERF1,IFI16,BYSL |
| 2.969e-07 | -15.03 | PPIA (peptidylprolyl isomerase A) | protein interactions | 5478 | 115 | 41 | 17029 | 2761 |
COX15,EWSR1,DCAF15,MYH9,CUL1,SDHA,RBM4,APP,PARK7,RPL23A,ZER1,CSDE1,RPA2,RB1,PCNA,GART,HUWE1,PIN1,RAD23B,COPS7B,TAGLN2,CFL1,SRPK2,LDHB,PPP3CA,LDHA,CUL3,VDAC1,MCM2,CBFB,MKNK1,CHMP4A,E2F4,PPP3R1,H2AFX,FUS,YY1,CDK2,ARRB2,IGBP1,N4BP2L2 |
| 3.008e-07 | -15.02 | UBXN1 (UBX domain protein 1) | protein interactions | 51035 | 148 | 49 | 17029 | 2761 |
UNK,UBR2,UFC1,MAGED1,UBXN1,BABAM1,CUL1,SPDL1,UBE2I,TWF2,BIRC2,NPLOC4,MCTS1,RPA2,CAPN2,HUWE1,CTPS1,NSFL1C,MAVS,AHCYL1,RLIM,PRPF19,USP34,UBQLN4,BIRC3,TUFM,CUL3,PSMA1,UBE4B,BRCA1,MCM2,GAR1,CLNS1A,ASF1B,BTBD1,RPA1,PLAA,PRPS2,KBTBD7,USP32,VCPIP1,SMAD1,IGBP1,UBE2C,SMURF1,CD81,FAF1,DDB1,SSSCA1 |
| 3.020e-07 | -15.01 | SSSCA1 (Sjogren syndrome/scleroderma autoantigen 1) | protein interactions | 10534 | 165 | 53 | 17029 | 2761 |
NPHP4,CYLD,TXN,KRBA1,POC1A,UFC1,SUMO2,UBXN1,TKT,LAGE3,UBQLN2,ATP6V1B2,AP3S1,STMN1,RAPGEF6,STAM,MYEF2,SRXN1,GTF2F1,DTL,ZBTB21,CCP110,THADA,TTC9C,ICE2,TAGLN2,CABLES2,TTLL12,STAT3,ZC3H3,TACC3,SMC4,USP34,FYTTD1,CCT2,DDX28,TIGD5,MAP7D1,UBE2V1,UBE4B,SMC2,EIF2A,SLTM,GEMIN5,TPD52L2,STAT6,PRDX5,ZRANB2,WDR76,RUVBL2,UBE2C,FAM208A,SSSCA1 |
| 3.062e-07 | -15.00 | SHEPARD_CRUSH_AND_BURN_MUTANT_DN | MSigDB lists | SHEPARD_CRUSH_AND_BURN_MUTANT_DN | 176 | 53 | 17377 | 2626 |
POU3F2,FOXM1,FAM76A,TPX2,CDCA3,KCTD17,KIF23,RACGAP1,HMGN3,KIF2C,NOTCH2,CCNB1,RLF,FBXO5,RTKN,OIP5,PTEN,MBD2,KIF14,PRC1,GTSE1,ST8SIA2,IFT46,TACC3,PHF20L1,TK1,PRIM2,ASPM,MKI67,DDX20,BMS1,CDCA2,AURKB,ANLN,SHCBP1,BORA,KIF11,KDM3A,MASTL,DDX17,DPYSL3,ATP1A1,SYNCRIP,CDC27,BIRC5,NEIL3,NFIL3,CEP55,NDE1,CCNB2,HDAC2,ZNF511,FUBP1 |
| 3.063e-07 | -15.00 | pancreas-carcinoid-endocrine_tumour-gastrinoma | COSMIC cancer mutations | pancreas-carcinoid-endocrine_tumour-gastrinoma | 10 | 9 | 17385 | 2587 |
GNAS,CDKN2C,NRAS,PTEN,KRAS,MEN1,SMAD4,HRAS,CDKN2A |
| 3.064e-07 | -15.00 | MODULE_22 | MSigDB lists | MODULE_22 | 34 | 18 | 17377 | 2626 |
NDUFA5,NDUFV2,ATP2C1,ATP6V0A1,NDUFA4,NDUFA7,NDUFB1,NDUFS4,ATP6V0B,NDUFV1,NDUFA2,ATP6V0C,NDUFS8,NDUFS5,NDUFA3,ATP6V0D1,ATP6V0E1,ATP6V1G1 |
| 3.115e-07 | -14.98 | regulation of cell cycle G2/M phase transition | biological process | GO:1902749 | 217 | 62 | 17256 | 2622 |
FGFR1OP,GPR132,MAPRE1,CLSPN,DYNLL1,MECP2,CENPF,BABAM1,DCTN2,TPX2,CUL1,HAUS4,CCNB1,BLM,PRKACA,PSMD9,RAB11A,HAUS2,APP,FANCI,DTL,PSMD2,PSMA6,PSMD1,BABAM2,CCP110,CENPJ,KIF14,GTSE1,H2AFY,FBXL7,CEP63,CDC25B,DCTN1,PLK1,BRD4,RBX1,PSMA8,TAOK1,PSMB7,MRNIP,PSMA1,BRCA1,AURKB,PSMB9,PSMB3,HAUS8,PSMC4,RAD51C,PCM1,RPS27A,PSMD8,PSMD3,ODF2,SSNA1,VPS4A,NDE1,ZNF830,CDK2,PSMC1,CSNK1D,TUBB |
| 3.136e-07 | -14.98 | SMN1 (survival of motor neuron 1, telomeric) | protein interactions | 6606 | 200 | 61 | 17029 | 2761 |
IMMT,RPS2,EWSR1,COPA,WDYHV1,HMGXB3,DHX9,THRAP3,ATP5F1B,SNRPD3,EXT2,HNRNPA2B1,FLAD1,ERH,SNUPN,KLHL5,PPIG,ZNF746,POP7,MSH2,HADHB,DUS2,GEMIN6,BCL2,MAST2,GEMIN4,FBL,STRAP,CDC5L,SNRPB,WDR18,RPL6,MKI67,CUL3,DDX20,SRSF5,PKM,GAR1,EIF3G,NMT2,POLR2A,DDX17,GEMIN5,RBM25,HNRNPR,LSM6,QARS,HNRNPH3,KMT2B,ACTB,DDX5,SRSF3,SNRPG,COPS6,MAP3K5,SNRNP70,RBBP4,COIL,HDAC2,GEMIN7,FUBP1 |
| 3.143e-07 | -14.97 | HSPB1 (heat shock protein family B (small) member 1) | protein interactions | 3315 | 410 | 106 | 17029 | 2761 |
CCNC,CYLD,PNISR,LUZP1,ZBTB37,MAGED1,OLA1,SMARCA4,UBE2I,STMN1,MAPK14,SDHA,KCMF1,RAD23A,HNRNPA2B1,PSMD1,PSMA6,NVL,UCHL5,DUT,ADCY9,POP7,CS,AP2B1,TTC3,ANAPC7,TARDBP,NFU1,EIF5,ATF2,ASB6,CDC5L,RYBP,PRPF19,SRP72,CLCN3,SNRNP200,CDC123,RBX1,CRNKL1,CUL3,HNRNPF,GLO1,BRCA1,PITPNB,MCM2,RPSA,OPTN,GLOD4,PAF1,C11orf98,AHNAK,HSPA4,GRIPAP1,GOLGA8A,IARS2,DMWD,PSMC1,MYL12B,NSMCE4A,TKT,KLC1,CYCS,ZNRF3,CDC73,C12orf10,RPA2,ADD3,HUWE1,ATIC,PELO,EFTUD2,AHCY,MRPL40,PTGES3,PPA1,EEF1D,RPAP3,TXNL1,HMGN5,CSRP1,MAPKAPK3,AMD1,ARMT1,PKM,FXR1,EIF4G2,TARS,ISG15,RPA1,XRCC5,HAUS8,NAP1L1,UAP1,RBM25,PDLIM1,MFAP1,HNRNPH3,PITPNA,YWHAZ,RBPJ,YWHAH,ECPAS,IGBP1,RNF114,SMARCD1 |
| 3.150e-07 | -14.97 | SMARCC2 (SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 2) | protein interactions | 6601 | 144 | 48 | 17029 | 2761 |
SART1,EWSR1,ARID2,DCTN2,CSNK2A1,SMARCA4,TOP2B,ARID1B,TERF2IP,RPA2,TFAP4,BANF1,TXLNA,BRD7,SS18L1,NUP153,MCPH1,SMARCE1,CARM1,CDC5L,PHF10,CUL3,ATXN1,RCOR1,TOPORS,NFATC2,BRCA1,ARID1A,PBRM1,PCGF1,RPA1,DDX17,SMAD2,CHD3,BCL7C,BAZ1B,KHSRP,KPNA2,ACTB,PSAP,ARRB2,BRD9,TAF6,TERF1,IFI16,HDAC2,FUBP1,SMARCD1 |
| 3.157e-07 | -14.97 | GSE19401_NAIVE_VS_IMMUNIZED_MOUSE_PLN_FOLLICULAR_DC_DN | MSigDB lists | GSE19401_NAIVE_VS_IMMUNIZED_MOUSE_PLN_FOLLICULAR_DC_DN | 190 | 56 | 17377 | 2626 |
MIF,POLA2,GLT8D1,CDC40,SCAMP3,PHB2,TRIO,UCK2,KCTD17,BTN3A1,XPO7,GGA2,MAPK14,SLC20A1,SDHA,GIT2,MRPL19,TUBGCP2,GNS,FARSA,ATIC,MSH2,ATP6V0A2,PDCD2,ARHGEF2,ZNF710,GPX4,VPS13B,VOPP1,KDM3B,ZDHHC18,DDX28,DEAF1,ACP2,FRAT2,ATP6V0A1,PSMB9,ZFAND5,POLR2A,CYB5A,RXRB,ZMYM3,MYO1F,HHEX,CSK,ACOX1,OAZ2,STAT1,GLG1,OGT,ARAP1,WDR7,USP20,TCOF1,RBBP4,LTA4H |
| 3.157e-07 | -14.97 | GSE2770_UNTREATED_VS_IL4_TREATED_ACT_CD4_TCELL_2H_DN | MSigDB lists | GSE2770_UNTREATED_VS_IL4_TREATED_ACT_CD4_TCELL_2H_DN | 190 | 56 | 17377 | 2626 |
MIF,NSMCE4A,CHTF18,RAE1,FAM76A,PXMP2,HAUS4,POMP,COMMD5,PSMD9,PNO1,PRPF18,SSR1,FANCL,STARD9,PSMA6,MED8,CBWD2,PTEN,TIMM23,DNAAF2,TTC9C,LPIN2,EFTUD2,MSH2,NAA50,TIMELESS,FEM1B,KIF22,PRADC1,ARL5A,HTRA2,RNLS,FDFT1,DDX28,EIF3L,MND1,MAPRE2,LAP3,GOPC,NSUN2,KCTD20,CCDC34,PSMG1,ODC1,TMEM184C,GALNT2,POLE,ORMDL2,TONSL,QARS,NSMCE2,MRPL27,E2F2,TAF6,FAM83G |
| 3.194e-07 | -14.96 | Disease | REACTOME pathways | R-HSA-1643685 | 859 | 196 | 10287 | 1696 |
MIB2,CCNC,FGFR1OP,PDCD6IP,NUP188,AGRN,TSC2,NF1,ADAM10,MCCC1,CUL1,GYG1,SND1,RPL23A,CALM2,CDK5,RAP1A,PSMD1,NUP210,PIK3R2,AP1M1,AP2B1,NUP153,CDC25B,TCEA1,FGFR1OP2,SEH1L,CDC37,MLST8,NRAS,APH1A,RBX1,AKT2,ELOA,LRP5,SLC25A5,RPL37,SMAD2,RPS27A,PSMD8,AXIN1,RPS14,MYO18A,KPNA2,VPS4A,ARRB2,PSMC1,RPS26,CCDC59,HDAC2,AAAS,CAPN1,SSRP1,RPS15,MUT,AGTRAP,POLR2K,SDC2,RPL15,NOTCH2,APH1B,PSMD9,TTF1,LMNA,NUP205,FKBP1A,HDAC7,BANF1,MAML1,CPSF4,NUP85,POLR2I,AGGF1,ERLIN1,RPS10,RPL6,PSMA1,RPS24,KRAS,SYVN1,FXR1,MAP2K2,MTR,ISG15,PSMB3,NMT2,PSMC4,RPL36,XRCC5,DERL1,KPNA1,POLR2J,GOLGA2,CSK,NUP62,NUP58,ZC3HAV1,MMACHC,NDC1,CHMP2A,RPLP2,CAST,RAF1,RAC1,AP1B1,STAM,APP,CD320,EPM2A,RPL11,VAV1,MDM2,PSMA6,SHC1,GRSF1,CLCN6,NUP107,CDKN1B,RPL29,RPL35,POLR2L,POLR2G,PSMA8,PSMB7,POLR2D,RPL38,NUP155,CHMP2B,PSMB9,RPS9,RPSA,SUPT16H,PPP2CA,TAF2,CHMP4A,PPP2R5A,PSMD3,SEL1L,STAT1,RPLP1,AP1S1,CHMP4B,TICAM1,FAU,XRCC4,MAPK1,AP2S1,SMAD4,NCOR2,CTDP1,RPS2,RAE1,NUP54,TRAK1,BRAP,CBLL1,ARF1,AKT1S1,CSNK1A1,FOXO3,FZD6,HLA-A,GTF2F1,CCNK,CAPN2,PSMD2,FGFR3,RPL17,PTPN11,RPL19,CREB1,GTF2H2,STAT3,RPL22L1,RNF5,TGFB1,PDPK1,ADAM17,KAT2A,RPL8,RANGAP1,PACS1,RPL27A,MACF1,PRDX1,POLR2A,MAPK3,HGS,KPNA4,RPL32,ELMO1,RBPJ,TAF12,CHMP7,TAF6,HRAS |
| 3.246e-07 | -14.94 | bounding membrane of organelle | cellular component | GO:0098588 | 2039 | 380 | 18223 | 2701 |
RAB14,TMED7,ADAM10,ABCC10,TAP1,TMEM109,TGOLN2,SYNRG,RIC1,CMTM6,GLMP,NAPG,ASAP2,DBNDD1,RAB4A,AP1M1,DNM2,AP2B1,CISD2,MARCH2,TFG,RHBDD2,MGAT5,SEH1L,KCNAB2,PGAP2,BAK1,USO1,TMEM115,RHOBTB3,NRAS,ATG9A,MCL1,GALNT7,SLC17A5,NUTF2,MCFD2,SLC50A1,RAB22A,PLEKHF2,RAB2B,AHNAK,WDR11,TMED10,RPS27A,MYO18A,ATP6V0C,ST3GAL2,CHPF2,RTN3,B4GALT2,SVIP,DNAJC5,SCOC,GGA1,HLA-E,CCZ1,ACAP1,RAB23,B4GALT1,PXMP2,NOTCH2,SLC35B1,MAN2B1,TMED3,PSEN1,TMEM165,COPG2,VPS25,COPB2,TMEM179B,FKBP1A,CD59,RNF121,SNX18,ZNRF2,TPST1,ATP6V0A2,PIKFYVE,LPCAT1,PPP6R1,TMED2,NAGPA,SIGMAR1,MAN1B1,USF3,MFNG,GORASP2,ADRB2,MTX1,TOMM40,GOSR1,MAP2K2,CYB5A,RHOB,PI4K2A,AKAP1,SEC31A,CAT,DERL1,SCARB2,OSBPL11,GOLGA2,NSF,ERGIC3,ARAP1,APPL2,SAMD8,SMPD4,PPP6R3,SNX14,EXOC3,RHOG,ABCA3,SYS1,RAB11B,RAF1,RAC1,GPR89A,TMEM97,VTI1A,STARD7,SLC39A13,RXYLT1,SLC35B2,BCL2L1,SLC25A44,SNN,AP1B1,GNB2,APP,STAM,CPNE3,CD320,MOAP1,APLP2,RAB21,ATP2A2,MTMR4,CLCN6,BRI3,TAP2,MAVS,ATF2,TMEM9,GCC1,TMBIM1,ATP6V1G1,ENPP4,SNX8,CPNE1,SEC61B,GOPC,CUL3,VDAC2,ATP6V0A1,PKMYT1,RAB1A,AP4E1,ERC1,ANKZF1,ALDH3B1,PEX5,CHMP4A,DDOST,RAB24,GOLGA8A,TICAM1,ATF6,B4GALT3,CSNK1D,TMBIM4,ANXA6,MANBA,B4GALT5,FLOT1,AGPAT3,FOXO3,RAB11A,HLA-A,PIP5K1C,PDCD10,FUT8,ST8SIA2,TPCN1,MTX2,MFSD12,MOB4,RHOT1,SPPL2B,PICALM,SH3GLB1,YIF1A,NUCB1,HGS,MAGT1,ATP5MC3,CCZ1B,WNT5B,ACOX1,STX18,PML,LRPPRC,PSAP,WDR91,VPS29,GPR89B,SNAPIN,MTX3,COPA,CDIPT,BECN1,RUFY1,MAP1LC3B,SEC16A,PCYOX1L,RAB8A,RAP1A,CDC42,RAB35,SLC44A1,SRI,HADHB,ZFYVE27,SLC35C2,TRIM14,DRAM2,WDR41,MIOS,APH1A,CYSTM1,PITPNB,STX16,RAB5B,RHEB,NECAP2,OPTN,MAN2A2,AGPAT2,GRIPAP1,GALNT10,ROCK1,VPS4A,PIEZO1,CLN3,CHPT1,RPS26,ATP6V0E1,NAA60,STARD3NL,UBE2D3,AGTRAP,PHB2,GORASP1,CDIP1,LAMTOR3,PCSK7,RAB6A,B4GALT4,QSOX2,C1GALT1,TIGAR,VMP1,ARL6IP1,BCL2,TMEM8A,ATP6V0D1,KDELR1,PREB,ABCC1,CYTH1,TRAPPC9,ACSL3,GBA,ZDHHC3,APPL1,RMC1,EVC2,GOLGA4,GALNT2,SNAP23,LAMTOR4,ZDHHC7,CTSA,EHD4,NIPSNAP2,UNC13C,SNX27,CHMP2A,TOMM20,CORO7,GNPNAT1,CHERP,DYNLL1,COPE,SLC2A1,RRAGC,ZFYVE21,ATP6V1B2,BCAP31,EXT2,MIEF1,ANKRD28,ATP6V0B,MDM2,SAR1A,WDR44,PPP6C,RPN2,CORO1A,CYB5R1,LMAN1,CLTB,MOSPD1,EBAG9,CHP1,ACSL5,SNX25,CLCN3,RAB7A,VDAC1,CHMP2B,PEF1,SURF4,TAB2,SCAP,TOMM6,WDR59,CANT1,AP1S1,CHMP4B,SCARB1,AP2S1,GOLIM4,GOLPH3L,SCYL1,TMX3,VPS45,LETMD1,ARFIP2,ARF1,GGA2,SCYL2,TFRC,MAN1A1,SPPL2A,SEC24C,SLC35B4,ZDHHC13,YIF1B,ABCD1,SLC35A1,CAMK2G,B3GALT6,MLEC,RHOA,ACP2,SNX2,ATP2C1,COG1,RFFL,WDR81,PNPLA8,RHOT2,NEU1,MFN2,HLA-B,RAB18,ATP6V1D,PDCD6,SEC23IP,GOLGA7,SNAP29,PGRMC1,GLG1,PKD2,ATP6V1C1,PLOD3,CHMP7,HRAS |
| 3.248e-07 | -14.94 | GO_REPLICATION_FORK | MSigDB lists | GO_REPLICATION_FORK | 62 | 26 | 17377 | 2626 |
POLA2,RFC3,MCM10,PRIM2,HELB,RFC2,GINS4,RPA1,PRIM1,RPA2,RAD51C,PCNA,POLE,RAD18,TONSL,XPA,XRCC2,H2AFX,BAZ1B,XRCC3,TOP1MT,DNMT1,PURA,RAD51D,CDC5L,PRPF19 |
| 3.249e-07 | -14.94 | REACTOME_CELL_CYCLE_CHECKPOINTS | MSigDB lists | REACTOME_CELL_CYCLE_CHECKPOINTS | 110 | 38 | 17377 | 2626 |
MCM10,DBF4,ORC1,CCNB1,PSMD9,RPA2,PSMD2,MDM2,PSMA6,PSMD1,MCM5,CDKN1B,ANAPC7,ORC3,RFC3,PSMA8,PSMB7,PSMA1,ANAPC2,CDC6,MCM2,CDC23,PSMB9,RFC2,PSMB3,RPA1,PSMC4,CDC16,CDC27,RPS27A,PSMD3,PSMD8,CHEK2,CCNB2,UBE2C,CDK2,PSMC1,ANAPC4 |
| 3.252e-07 | -14.94 | NFATC2 (nuclear factor of activated T cells 2) | protein interactions | 4773 | 187 | 58 | 17029 | 2761 |
TCF12,HSPH1,MRPL39,SMARCA4,KIF2C,PPP3CB,SDHA,GNB2,WDR48,RPA2,TFAP4,IRF4,RB1,PIN1,MTA1,ETV6,H2AFY,CREB1,ALDH18A1,GTF2H2,SMARCE1,TIMM50,NUDC,CSTF1,PLK1,RFC3,FOXK1,PRKDC,IDH3A,BTAF1,MTA2,TLK1,TUFM,RCOR1,NFATC2,NFATC2IP,DNAJA1,ARID1A,USP22,MEF2D,MCM2,RFC2,MBD3,RPA1,XRCC5,CBX3,MTHFD2,MAFK,PPP3R1,CABIN1,YWHAZ,BEND3,RBBP4,IDH3B,IFI16,CSNK1D,SSRP1,SMARCD1 |
| 3.287e-07 | -14.93 | RPL22 (ribosomal protein L22) | protein interactions | 6146 | 140 | 47 | 17029 | 2761 |
RPS15,RPS2,CYLD,RPLP2,HEXB,MYH9,RPL15,CUL1,MAPK14,CDC73,RPL11,RPL23A,CDC42,RPL17,HUWE1,AHSA1,NSFL1C,RPL19,TARDBP,STRAP,LUC7L2,HNRNPM,SRPK2,RPL35,RPS10,RPL6,CUL3,ILF3,RPL8,RPL38,RPS24,MCM2,RPL27A,RPS9,DHX15,RPSA,PHF6,CAND1,RPL36,RPS27A,RPS14,WDR76,CDK2,ARRB2,SMURF1,CD81,RPS26 |
| 3.309e-07 | -14.92 | regulation of mRNA processing | biological process | GO:0050684 | 118 | 40 | 17256 | 2622 |
SRSF6,RBM8A,DHX9,TIA1,JMJD6,THRAP3,CCNB1,CDK11B,SAFB2,RBM4,CDC73,PAPOLA,HNRNPA2B1,NSRP1,SRSF4,TRA2B,CTR9,CPSF4,AHCYL1,RBM15B,SRPK2,SRSF10,PRPF19,YTHDC1,RBM42,RNPS1,SMU1,SREK1,CDK11A,SLTM,SNRPA,IWS1,DDX17,PAF1,RBM25,SAFB,RBMX,DDX5,SRSF3,SNRNP70 |
| 3.314e-07 | -14.92 | GO_REGULATION_OF_CELLULAR_PROTEIN_LOCALIZATION | MSigDB lists | GO_REGULATION_OF_CELLULAR_PROTEIN_LOCALIZATION | 523 | 122 | 17377 | 2626 |
ZBED3,RHOG,CYLD,TXN,CHERP,RAB11B,NF1,ZDHHC8,DYNLL1,ANK3,STARD7,PLAGL2,SIRT2,BCL2L1,CCNB1,PRKACA,MAPK14,BECN1,PARK7,BCAP31,CDK5,MDM2,SP100,CDC42,RALB,PIN1,PIK3R2,SRI,PARL,MAVS,CYB5R1,TP53BP2,GPD1L,OGG1,TMBIM1,KCNAB2,HTRA2,PLK3,PLK1,CCT2,TRIM8,AKT2,KAT7,GOPC,PSMB7,EZR,BRCA1,NUTF2,SOX4,EDEM2,TRIM28,USP36,PPP2R5A,TONSL,PSMD8,AXIN1,ITGB1,OGT,STK11,ZNF268,DVL1,VPS4A,SMAD4,OAZ1,NUMB,SVIP,DDX58,UBE2D3,HSPH1,NKD2,RAB23,NUP54,CIB1,RACGAP1,PPP3CB,SPAG5,LMNA,KIF5B,RB1,HUWE1,PTPN11,AXIN2,FAM89B,GTSE1,H2AFY,ATG13,MDFIC,BCL2,HNRNPM,PDPK1,TGFB1,GCC2,PPP3CA,RHOA,KAT2A,ACSL3,RANGAP1,CCT8,APPL1,SH3GLB1,PRDX1,AKAP1,NUCB1,KEAP1,KPNA1,PCM1,CSK,OAZ2,TFDP1,CDCA5,PML,E2F1,PPP3R1,NUP62,PKD2,YWHAZ,RUFY3,PARP10,YWHAH,TERF1,CDKN2A,FAF1 |
| 3.316e-07 | -14.92 | GSE5099_MONOCYTE_VS_CLASSICAL_M1_MACROPHAGE_DN | MSigDB lists | GSE5099_MONOCYTE_VS_CLASSICAL_M1_MACROPHAGE_DN | 181 | 54 | 17377 | 2626 |
MIF,IER2,HSPH1,CORO7,TP53RK,EWSR1,GMFG,HEXB,BRAP,ABCB10,NUF2,RGS2,PARK7,MXD1,FAM192A,CENPJ,PPIG,ETV6,CS,CTDSP2,EIF5A,SLC39A9,PSPC1,WDR1,ZMYND11,ILF3,WDHD1,EMP3,SRSF5,RIT1,RAB1A,STX16,EIF4H,HAGH,API5,DHX15,SMAP2,ASF1B,RHBDF2,MAGED2,GNAS,HLA-B,SMAD2,ERGIC3,EIF2D,PROSER1,DBI,H2AFX,PDXK,PSAP,SNRNP70,EHD4,PDSS2,HIGD2A |
| 3.316e-07 | -14.92 | GSE1460_CORD_VS_ADULT_BLOOD_NAIVE_CD4_TCELL_DN | MSigDB lists | GSE1460_CORD_VS_ADULT_BLOOD_NAIVE_CD4_TCELL_DN | 181 | 54 | 17377 | 2626 |
MBD1,POU3F2,SEPHS2,PPCS,SH2D3A,UGP2,GORASP1,SF3B1,HABP4,AP3M2,CUL1,UBQLN2,SUPT7L,ATP6V1B2,MAPK14,GGPS1,MAP1LC3B,APH1B,PCBP1,REEP5,PABPC4,NPLOC4,SEC11A,DAD1,RBM34,TARDBP,SGCB,GPD1L,SMARCE1,ACSL5,SHOC2,HARS,GABPA,WDR1,GMFB,HNRNPF,CRNKL1,EZR,PSMG1,GORASP2,UBE4B,PSMB9,EIF3H,PAF1,QARS,FN3KRP,ACAT1,MRFAP1L1,DDX5,PPP6R2,HEXA,IGBP1,PURA,APOL2 |
| 3.316e-07 | -14.92 | GSE41867_NAIVE_VS_DAY15_LCMV_EFFECTOR_CD8_TCELL_UP | MSigDB lists | GSE41867_NAIVE_VS_DAY15_LCMV_EFFECTOR_CD8_TCELL_UP | 181 | 54 | 17377 | 2626 |
GCLM,DDX47,NUP188,SCOC,POLR2K,PRKCSH,RAE1,EIF3D,PMS2,SIKE1,NANS,C2orf49,RAP1A,SNUPN,MED8,RAB35,PIGG,MSH2,YBX1,ANAPC7,PCYT2,CYB5R1,CENPM,CLTB,MCMBP,TRIM14,TMX1,MED22,AATF,RNASEH2C,CDC123,AACS,SMU1,CCDC34,BMS1,OGFR,MBD3,ABCF1,MAP2K2,CLNS1A,XRCC5,HSPB11,MID1IP1,GOLGA7,NIP7,LSM6,TBL3,UBXN2B,NFIL3,LRPPRC,WDR76,SASS6,FAF1,DDX52 |
| 3.371e-07 | -14.90 | GO_UBIQUITIN_LIKE_PROTEIN_LIGASE_BINDING | MSigDB lists | GO_UBIQUITIN_LIKE_PROTEIN_LIGASE_BINDING | 257 | 70 | 17377 | 2626 |
USP7,ATXN3,KDM4A,SUMO2,UBE2Z,CUL1,UBE2I,BECN1,PRKACA,MAP1LC3B,LYN,MOAP1,FANCL,PA2G4,MDM2,CCDC50,RALB,PCBP2,CCT2,RBX1,CUL3,UBE2V1,BRCA1,DNAJA1,SLC25A5,TOLLIP,TRIM28,SMAD2,JAK1,RAD18,AXIN1,ATP6V0C,ATF6,CHEK2,CLU,TRAF5,ARRB2,TUBB,USP13,SCAMP3,DNAJB2,SHPRH,UBXN1,NKD2,SMC6,FZD6,NPLOC4,DDRGK1,RPA2,RB1,TANK,ZNF746,AXIN2,BCL2,UBE2M,RFFL,RANGAP1,ANAPC2,POLR2A,HSPA1B,MFN2,XRCC5,DERL1,PIAS2,PML,LRPPRC,YWHAZ,GPI,UBE2C,FAF1 |
| 3.499e-07 | -14.87 | RPLP0 (ribosomal protein lateral stalk subunit P0) | protein interactions | 6175 | 205 | 62 | 17029 | 2761 |
RPS15,RPS2,EWSR1,RPLP2,RPL15,CUL1,CSNK2A1,HAUS2,CDC73,RPL11,RPL23A,KRI1,RPA2,FARSA,PA2G4,IARS,PTEN,RPL17,HUWE1,RBM34,ZNF746,MSH2,NDUFS8,RPL19,RPN2,TARDBP,MRM3,PABPC1,HNRNPM,STAU1,RPL35,DDX24,VHL,IDH3A,RPS10,RPL6,CUL3,RPL8,RPL38,RPS24,DNAJA1,MCM2,RPL27A,RPS9,RPSA,PHF6,RPA1,RPL36,CAND1,RPL32,RPS27A,RPS14,ACOX1,QARS,RPLP1,RRS1,RBBP4,CDK2,ARRB2,CD81,RPS26,ZC3HAV1 |
| 3.503e-07 | -14.86 | KOINUMA_TARGETS_OF_SMAD2_OR_SMAD3 | MSigDB lists | KOINUMA_TARGETS_OF_SMAD2_OR_SMAD3 | 779 | 169 | 17377 | 2626 |
TXN,GLUD1,FKBP2,BRIX1,SLC20A1,MBD4,PRNP,CDK5,DST,THADA,RAB4A,SRI,TRA2B,TCEA1,FAM86C1,TIPARP,PTPRK,COPS8,DEAF1,TRIM8,KLF10,SEPT9,MIOS,LNX2,MCL1,ARHGDIB,CDC6,SMC2,MCFD2,ANLN,RFC2,RHEB,ANKRD10,AHNAK,CDCA4,BRD2,CHD3,ITGB1,BAZ1B,ARRDC1,CLU,DNAJC30,SMAD1,CHPF2,FUBP1,C9orf78,DNAJB2,RHOC,CERK,MEF2A,SLC4A2,NOTCH2,DTL,CD59,FKBP1A,CCP110,INPP5A,INTS7,SSBP3,ZNF335,PPA1,ABHD2,IFRD1,AGGF1,ELL2,NQO2,MAN1B1,TYW1,ARID1A,PLEC,KDM3A,EIF4H,ZDHHC3,RXRB,RDH11,MASTL,PTPRF,SERTAD2,KPNA1,PDLIM1,RBM25,ETS2,POLR2J,SNAP23,NFIL3,SIAH2,DCAF11,YWHAZ,NANP,BTBD10,NDE1,C11orf1,MZT2B,WASF2,TRAF7,ARID2,IVNS1ABP,CAST,SLC39A13,MYH9,HCFC1R1,PCBP1,EXT2,HNRNPA2B1,CD3EAP,NSFL1C,FAM76B,TMBIM1,NXT1,MAPRE2,DRAP1,BTG2,CIRBP,VDAC2,ATXN1,HERPUD2,H2AFV,MRPL2,ACYP1,CORO1C,MAFK,FASTK,CHMP4B,MBOAT1,TRIM32,SMURF1,PPP2R2D,TUBB,DNAJC2,SESTD1,ZFP91,FLOT1,PAWR,AP3S1,ETS1,FOXO3,RMI1,COQ4,FEM1B,TAGLN2,MAP3K14,GTF2H2,MOB4,PPP3CA,TCTEX1D2,NET1,DENND1B,ABCF2,PARP4,RANGAP1,WDR81,KLF6,PICALM,ECH1,PRDX1,CBX3,MFN2,KPNA4,ATP6V1D,ATAD2,ACOX1,HNRNPH3,MAPK6,CTBS,PML,AEN,SRSF3,RBPJ,S100PBP |
| 3.510e-07 | -14.86 | RAB1A (RAB1A, member RAS oncogene family) | protein interactions | 5861 | 170 | 54 | 17029 | 2761 |
UNK,TXN,TM9SF4,RAB11B,RAB6A,ARF1,STMN1,RAB11A,RIC1,PARK7,CDC73,BCAP31,RPA2,RPN1,RAB8A,RAP1A,CDC42,AHSA1,DUT,GTSE1,NDUFB9,NDUFS8,RPN2,PCYT2,CYC1,TECR,CREB1,MTPN,TMED2,LDHB,TRAPPC13,USO1,RAB7A,VDAC2,LDHA,JTB,RABIF,GORASP2,CAPZA2,RAB5B,RAB2B,RPA1,STOML2,RAB18,TBC1D17,ATP1A1,SEC23IP,GOLGA2,TMED10,LRPPRC,PTAR1,CSNK1D,SSRP1,FUBP1 |
| 3.539e-07 | -14.85 | GO_PROTEIN_TARGETING_TO_MEMBRANE | MSigDB lists | GO_PROTEIN_TARGETING_TO_MEMBRANE | 154 | 48 | 17377 | 2626 |
RPS15,RPS2,RPLP2,ANK3,NKD2,NUP54,RPL15,RPL11,SSR1,RPL23A,ATG4A,RPL17,ATG3,ARL6IP1,RPL19,PACS2,TMED2,SRP72,RPL29,RPL35,RPS10,RPL6,RPL8,RPL38,RPS24,SSR2,PACS1,NUP155,RAB3IP,ICMT,RPL27A,RPS9,RPSA,RPL36,RPL37,TRAM2,PEX5,CHMP4A,SEC61A1,RPL32,RPS27A,RPS14,RPLP1,CHMP4B,FAU,SMURF1,RPS26,PARD3 |
| 3.568e-07 | -14.85 | MODULE_244 | MSigDB lists | MODULE_244 | 186 | 55 | 17377 | 2626 |
SEPHS2,KIF3B,KARS,POLR2K,KIF23,CSNK2A1,KIF2C,ORC1,BLM,MAPK14,CDK5,ABL2,PCNA,IARS,EIF4A3,KIF14,MSH2,KIF22,TAP2,ABCC1,SRPK2,PLK1,TK1,RFC3,PRIM2,HARS,MAPKAPK3,MAP4K4,POLR2D,MKI67,SMC2,RFC2,KIF11,MAP2K2,CCT8,MAT2A,PSMC4,XRCC5,PRIM1,DDX23,DDX17,RAD51C,POLE,POLR2J,DCK,LIMK1,QARS,STK38,MAPK6,KHSRP,STK11,XRCC3,CHEK2,CDK2,PRPF4B |
| 3.568e-07 | -14.85 | GSE24726_WT_VS_E2-2_KO_PDC_UP | MSigDB lists | GSE24726_WT_VS_E2-2_KO_PDC_UP | 186 | 55 | 17377 | 2626 |
ZNF496,UBN1,CDT1,TMX4,FAM76A,MEF2A,MXD4,FOXO3,CDKN2C,SNRNP25,TNS3,CLIC4,GATC,STRBP,PHF14,TTC3,RBM15,RPL22L1,DRAM2,HP1BP3,NIPAL3,GCC2,ERMP1,MAPRE2,RHOBTB3,CREG1,RAD51AP1,RDH10,SLC16A7,GBA,WIPF1,RTF1,NUSAP1,NFATC2,SHCBP1,POLG2,ADSS,EIF3K,SLCO4A1,NAP1L1,HINT1,RBL1,OSBPL8,EIF2D,CDCA5,UHRF2,ANP32E,ATF6,CHEK2,MAP3K5,TFDP2,ATP6V1C1,SASS6,YWHAH,MZT2B |
| 3.568e-07 | -14.85 | GSE2770_IL12_AND_TGFB_VS_IL4_TREATED_ACT_CD4_TCELL_6H_UP | MSigDB lists | GSE2770_IL12_AND_TGFB_VS_IL4_TREATED_ACT_CD4_TCELL_6H_UP | 186 | 55 | 17377 | 2626 |
BCCIP,KARS,PDAP1,MUM1,HNRNPUL2,TPX2,KIF2C,NANS,FKBP2,GGA2,CDC73,RAD23A,MOAP1,CLUAP1,CCNA2,EFTUD2,PRC1,CDC25B,APOOL,MYO5A,TMX1,TIMM50,PLK1,TDP1,SGCE,TK1,PRIM2,CDC123,KAT7,KCTD20,DNAJC9,AURKB,SMC2,PPFIA3,PCGF1,ANLN,CAND1,PAF1,NUCB1,KEAP1,KIF18A,KPNA1,MRPL55,RBL1,NSMCE2,NFIL3,PPA2,C4orf46,MDH1,RUVBL2,CDK2,E2F2,HIGD2A,TUBB,NXT2 |
| 3.570e-07 | -14.85 | proteolysis | biological process | GO:0006508 | 1243 | 252 | 17256 | 2622 |
PDCD6IP,ADAM10,CUL1,UBE2Z,USP39,NHLRC3,SIRT2,UBQLN2,CCNB1,UBE2I,USP48,BECN1,BIRC2,PARK7,RNF103,FBXO22,PCYOX1L,PSMD1,RAD23B,SRI,FBXW2,JOSD1,RHBDD2,SENP1,PCBP2,USP34,PLK1,COPS8,BAK1,RBX1,LAP3,APH1A,VHL,LACTB,TOPORS,USP22,AURKB,BRCA1,CCNF,USP21,STOML2,SMAD2,RPS27A,PSMD8,AXIN1,TPP2,OGT,ATE1,ARRDC1,ADAM9,ACTB,VPS4A,KLHL42,FBXL3,OSGEPL1,CLN3,SMAD1,COPS6,ARRB2,NGLY1,PSMC1,LONP2,CAPN1,DDX58,UBE2D3,RMND5A,TMUB1,CLSPN,UBXN1,KCTD17,PCSK7,PM20D2,XPNPEP3,ZNRF3,ASXL2,PSMD9,APH1B,PSEN1,VPS25,RHBDD1,WDR48,NPLOC4,ATG4A,CFLAR,DTL,RNF121,CCP110,ZNRF2,FBXO7,TENM3,FBXL7,YBX1,RNF135,ZRANB1,FOXK1,CPQ,ERLIN1,MAN1B1,USP10,PSMA1,UBE4B,SYVN1,ADRB2,CYFIP2,ARMC8,MAP2K2,PSMB3,ISG15,PSMC4,DERL1,CDC27,EPOP,KLHL15,RBMX,SIAH2,DCAF11,USP32,VCPIP1,CTSA,YY1,ECPAS,RNF139,USP7,TOMM20,ATXN3,CYLD,UBR2,PTTG1,MYH9,INO80E,STAM,RAD23A,USP5,SEC11A,UBXN2A,CCNA2,PSMA6,FBXL6,MDM2,BABAM2,SIAH1,ABRAXAS2,MTA1,KIF14,UCHL5,SOCS6,NSFL1C,PARL,ANAPC7,TTC3,MAVS,SPSB3,HTRA2,RLIM,PRPF19,CPNE1,SEC61B,ERMP1,BIRC3,PSMA8,PSMB7,CUL3,NLN,KDM1B,EDEM2,CDC23,PEF1,PSMB9,TOLLIP,RHBDF2,USP36,BTBD1,AMZ2,ANKZF1,DNAJC10,CDC16,IDE,UBXN2B,PSMD3,ARNTL,RNF38,SEL1L,CHMP4B,TRIM32,DMWD,USP11,SMURF1,PITRM1,LTA4H,SMAD4,LRP8,USP53,ADAM23,USP13,OTUD5,TRIP12,CASP6,BABAM1,SRGN,SDF2L1,UBE4A,CSNK1A1,DNAJB9,WWP2,SPPL2A,FBXO3,CAPN2,PSMD2,CTSS,KLHL20,PTEN,TANK,AXIN2,GTSE1,LTN1,COPS7B,FBXL19,RNF5,TGFB1,ADAM17,RHOA,KAT2A,TNFAIP3,USP42,RFFL,FBXO9,ANAPC2,WDR81,OTUD3,RHOT1,SPPL2B,FADD,CTSL,FBXO21,KEAP1,PDCD6,HGS,PLAA,CAPN7,PML,USP20,PPP1R11,MBD6,SPCS3,WDR91,PREPL,UBE2C,ESPL1,ANAPC4,IFI16,DDB1,FAF1 |
| 3.579e-07 | -14.84 | GO_STRUCTURAL_CONSTITUENT_OF_RIBOSOME | MSigDB lists | GO_STRUCTURAL_CONSTITUENT_OF_RIBOSOME | 200 | 58 | 17377 | 2626 |
RPS15,RPS2,MRPL9,MRPL42,RPLP2,MRPS2,MRPS15,RPL15,SLC25A12,SLC25A44,SLC25A43,MRPL19,SLC25A37,RPL11,RPL23A,SLC25A36,RPL17,MRPL34,RPL19,MRPL21,MRPL11,RPL22L1,MRPL32,SLC25A1,RPL29,RPL35,MRPL12,RPS10,MRPL43,RPL6,RPL8,RPL38,RPS24,SLC25A22,MRPL16,NDUFA7,RPL27A,SLC25A5,MRPS14,RPS9,RPSA,RPL36,RPL37,MRPL2,DAP3,MRPL55,RPL32,RPS27A,RPS14,MRPL27,RPLP1,SLC25A19,FAU,MRPL13,RPS26,SLC25A39,MRPL3,SLC25A33 |
| 3.591e-07 | -14.84 | Separation of Sister Chromatids | REACTOME pathways | R-HSA-2467813 | 168 | 54 | 10287 | 1696 |
MAPRE1,PTTG1,CENPF,CDCA8,NUF2,KIF2C,PMF1,SPDL1,PSMD9,MIS12,PSMD2,PSMD1,SMC3,AHCTF1,PSMA6,NUP107,PDS5B,ANAPC7,KNTC1,CENPM,NUP85,SEH1L,NUDC,PLK1,PSMA8,TAOK1,PSMB7,PSMA1,ANAPC2,RANGAP1,AURKB,CDC23,PSMB9,PSMB3,CENPU,PSMC4,PPP2CA,KIF2A,KIF18A,CDC16,PPP2R5A,DSN1,CDC27,BIRC5,RPS27A,PSMD8,PSMD3,CDCA5,CENPT,NDE1,UBE2C,PSMC1,ESPL1,ANAPC4 |
| 3.622e-07 | -14.83 | mitotic cytokinesis | biological process | GO:0000281 | 62 | 26 | 17256 | 2622 |
PLK1,PDCD6IP,RHOA,SEPT9,RHOC,ANK3,JTB,KIF23,SEPT8,RACGAP1,NUSAP1,CNTROB,SEPT7,ANLN,STMN1,RHOB,RTKN,TMEM250,SEPT1,SNX18,RAB35,CEP55,SEPT11,CHMP4B,ESPL1,CFL1 |
| 3.626e-07 | -14.83 | positive regulation of macromolecule metabolic process | biological process | GO:0010604 | 3113 | 565 | 17256 | 2622 |
MAP3K7CL,HEXB,XIAP,CCNL2,PPP1R16B,EDRF1,FBXO22,CDK5,CALM2,USF1,DNM2,FNIP2,ECD,ZNRD1,TIPARP,SENP1,MLST8,BAK1,PLK3,ERCC1,AATF,GABPA,TOPORS,DCUN1D5,SLC50A1,ARF4,STOML2,BRMS1,SMAD2,RPS27A,AXIN1,OGT,RNASEL,TFDP2,SMAD1,E2F2,OAZ1,HIVEP3,CLSPN,GGA1,PHF23,DHX9,EZH1,EIF2AK4,PSMD9,PARN,CDC73,LMNA,DDRGK1,TFAP4,FOXN2,MYDGF,PABPC1,NUP85,PHKG2,NSUN4,FOXK1,RB1CC1,MAPKAPK3,MTA2,MYBL2,BCLAF1,SRSF5,ELK1,FNTA,ETS2,CSK,SETD3,RNF139,ALS2,EGLN1,RHOG,KARS,TRERF1,IVNS1ABP,ANK3,TPX2,MYH9,CREBL2,DAZAP2,PRKACA,ANKIB1,APP,SP100,MTA1,GMEB1,RNF19A,MAVS,ATF2,RBM15,CLN6,RPRD1B,ADCY7,PSRC1,POLR2L,KAT7,MAP4K4,WBP2,POLR2D,E2F3,CIRBP,CDCA2,MEF2D,RAB1A,DDX17,TAF2,PPP2CA,HIPK2,RPLP1,TICAM1,LRP8,USP13,RPS2,ZFP91,HABP4,FLOT1,ABHD14B,WDR5,ETS1,PDCD10,ITGB8,PRDM4,PDPK1,PPP3CA,TNFAIP3,JTB,ZP3,PICALM,KEAP1,GPS2,PITX1,PML,HMGB2,PSAP,CD81,USF2,YWHAH,THOC1,AGRN,AAMDC,GPBP1L1,PPP1R15B,FAM129A,CSNK2A1,NENF,S1PR2,BIRC2,FANCI,CREM,PRNP,TET3,PCNA,GLIS2,IL6ST,ZNF639,ETV6,PIK3R2,MYBL1,MTPN,RYBP,PLK1,SP3,EXOSC6,RBX1,MRPL12,EZR,CDC6,UBE2V1,LRP5,BRCA1,EAF2,USP21,E2F4,SOCS4,ADAM9,ACTB,DVL1,POT1,ZNF564,FUBP1,PHB2,NKD2,LAMTOR3,CTCF,CHCHD2,CDK13,PPP3CB,RLF,ASXL2,CRLF3,ARID1B,SUB1,RB1,MLX,TIGAR,SSBP3,ZNF746,CTR9,TIMELESS,MDFIC,RBM3,ICE2,MAML1,LDB1,UTP15,KRAS,MAP4K3,RTF1,NFATC2IP,IRF5,PSMC4,RXRB,SYNCRIP,NLRC5,TBPL1,RUVBL2,RNF114,USP7,TRAF7,FOXM1,SUMO2,LYN,DUSP22,PCBP1,BCAP31,RPL11,RAD23A,NRF1,MDM2,PIN1,PDCD2,TARDBP,SPIDR,DVL2,PRPF19,TIMP2,BIRC3,POLR2G,RAB7A,BTG2,NFATC2,SRSF1,IDE,SCAP,RBL1,TIMM17A,PLGRKT,NCOA1,H3F3A,SMAD4,BCL2L12,SLC30A9,DAP,CDT1,AGO2,NKRF,HMGN3,CSNK1A1,PAGR1,SCYL2,TFRC,IRF4,SS18L1,PTGES3,POLR1B,RHOA,HMGN5,PRKDC,PDCD6,NEK1,TWSG1,TFE3,E2F1,PKD2,RBPJ,NR2F2,UBE2C,IFI16,H2AFZ,ZNF496,TXN,CXXC1,YTHDF3,UBE2I,CCNB1,PARK7,GLMP,NOL11,FIZ1,TRA2B,CDC25B,DNMT1,CDC5L,KLF10,AKT2,MRNIP,AURKB,USP22,CBFB,RFC2,DOT1L,MAP3K4,HHEX,SLF1,ARRB2,NMD3,HDAC2,SVIP,DDX58,HSPH1,POLR2K,CHTF18,PRKAA1,GADD45G,CYCS,NOTCH2,PSEN1,METTL3,WDR48,CFLAR,FKBP1A,DAPK1,MSH2,LPCAT1,GNAI2,TMED2,TERF2,SOCS5,EIF5A,EXOSC9,ADRB2,ARID1A,CYFIP2,FXR1,PTTG1IP,KDM3A,CCT8,MAP2K2,TWISTNB,XRCC5,FAS,DERL1,HSPBP1,SERTAD2,GOLGA2,NSF,RBMX,CEBPG,ARAP1,PPP3R1,PIAS2,MAP3K5,YY1,CDK2,RNF14,ZC3HAV1,ATXN3,SF3B1,RAF1,RPS6KA1,EIF3D,RAC1,MAGED1,TERF2IP,CRKL,CCNA2,SHC1,RALB,LPIN2,ADCY9,MRPS27,CDKN1B,CDK12,ANKLE2,CCT2,BRD4,RFC3,CDC123,TAOK1,CUL3,EDF1,TRIM28,SERP1,SUPT16H,VEZF1,PPP2R5A,SAFB,STAT1,H2AFX,ATF6,TRIM32,EYA2,ATMIN,CSNK1D,POU3F2,NCOR2,MECP2,TCF3,BABAM1,SECISBP2,BLM,FOXO3,MAD2L2,GTF2F1,WWP2,CCNK,PTEN,PTPN11,AXIN2,CARF,MAP3K14,CREB1,CNOT6L,CITED2,MSH6,NCOA2,LONRF3,KAT2A,NEK7,ILF3,RFXANK,KLF6,MARK2,POLR2A,FADD,HGS,OAZ2,TFDP1,KHSRP,DDX5,DDB1,RORB,CCNC,ZBED3,ZNF76,IER2,HNRNPAB,KMT2E,SIRT2,UBQLN2,MAPK14,ZNF804A,RAP1A,EIF4A3,METTL14,TCEA1,ARID4A,CARM1,ELOF1,SRPK2,COPS8,DEAF1,NCK1,VHL,SOX4,UBTF,PAF1,BAZ1B,CAB39,STK11,ZNF268,CHEK2,ROCK1,CLU,PSMC1,PPP1R12A,GORASP1,CIB1,MEF2A,THRAP3,EPHX2,RHBDD1,APOPT1,DTL,NFATC3,MED10,YBX1,BCL2,ATP5IF1,ERLIN1,GBA,EIF2A,CAND1,NSMF,NFIL3,NUP62,ZFP90,SNRNP70,EHD4,TOB1,SMARCD1,TCF12,PRKAB1,ASH1L,IFI27L1,PLAGL2,SMARCA4,IRF3,PAIP1,USP5,HNRNPA2B1,RRN3,BABAM2,NVL,CD3EAP,KIF14,AKAP8,CHTOP,F2R,ABI1,HTRA2,CHP1,MOSPD1,POU2AF1,EDEM2,TOLLIP,PEF1,RPS9,HNRNPR,TAB2,STAT6,ARNTL,GADD45B,AKNA,MAPK1,SMURF1,NAT14,MIF,DNAJC2,EYA1,DBF4,KLF13,PAWR,DCUN1D4,FBXO5,FASTKD3,FGFR3,TANK,NABP2,BRD7,ARHGEF2,H2AFY,ATG13,STAT3,TGFB1,TELO2,COA3,HMGN1,ADAM17,DCAF6,PRKAR1B,MEN1,PRMT2,SYMPK,TFEB,HSPA1B,MAPK3,CNOT9,UPF1,ATAD2,OSBPL8,KMT2B,ZMIZ1,SLF2,HRAS |
| 3.641e-07 | -14.83 | respiratory chain complex | cellular component | GO:0098803 | 75 | 29 | 18223 | 2701 |
COX5B,NDUFA5,NDUFV2,NDUFS1,NDUFB6,UQCR10,DMAC2,NDUFA4,COX4I1,NDUFA7,NDUFB1,FOXRED1,SDHA,PARK7,NDUFS7,NDUFS4,SDHB,NDUFV1,NDUFA2,NDUFB4,NDUFA11,COX8A,COX5A,NDUFS8,UQCRH,NDUFB9,NDUFS5,CYC1,NDUFA3 |
| 3.727e-07 | -14.80 | TTTGCAC,MIR-19A,MIR-19B | MSigDB lists | TTTGCAC,MIR-19A,MIR-19B | 487 | 115 | 17377 | 2626 |
UBL3,SNX27,ZBTB10,CYLD,PLXNC1,IVNS1ABP,CAST,SUZ12,RAF1,C5orf30,CREBL2,TGOLN2,ATP6V1B2,MAPK14,LCLAT1,ELMOD2,LIN9,RAB21,RAP1A,ASAP2,KDM2A,WDR44,GRSF1,ADCY9,CS,TNPO2,SPTSSA,ZNF800,ADCY7,KLF10,WBP2,HNRNPF,PFKFB3,ATXN1,MEF2D,SOX4,CBFB,RAB5B,RAB2B,MID1IP1,BRWD1,FBXO28,SPATA2,STK38,FASTK,RNF38,OGT,RBMS1,CBLN2,CAB39,CHMP4B,ABCA1,RHEBL1,POU3F2,B4GALT5,ZFP91,SRSF6,MECP2,CCM2,MED13L,KLF13,ARGLU1,CDK13,DNAJB1,ZNF518A,ASXL2,JAKMIP1,KLHL20,BTF3L4,PRC1,AFF1,MDFIC,MAP3K14,PPP6R1,SOCS5,ELOVL5,ZDHHC18,MLEC,ELL2,WDR1,BTAF1,ZMYND11,MIER1,ATP2C1,MEMO1,CAMSAP1,ARHGEF12,SEPT7,ARMC8,MACF1,PATL1,APPL1,RHOB,AKAP1,ADSS,RAB18,TSC1,KPNA4,PLAA,L3MBTL3,CSNK1G1,PITX1,MAPK6,USP32,VCPIP1,ZDHHC7,IMPDH1,SLAIN1,CNOT6,ASNA1,PSAP,RGL1,MBD6,PPP6R2,NIPA1 |
| 3.736e-07 | -14.80 | GSE12366_GC_VS_NAIVE_BCELL_UP | MSigDB lists | GSE12366_GC_VS_NAIVE_BCELL_UP | 177 | 53 | 17377 | 2626 |
TMEM106C,H2AFZ,CHIC2,GMCL1,HMGN3,PARN,PABPC4,FBXO5,RBM17,TERF2IP,DTL,PCNA,CLIC4,AP3S2,MBD2,EXOSC1,MRPS27,KIF22,CENPM,PCBP2,GINS1,PLK1,POU2AF1,TDP1,MND1,SEC61B,DENND1B,PRKDC,CUL3,SLBP,SYVN1,SMC2,MCM2,ASB13,ASF1B,RPA1,MASTL,CDCA4,TXNDC16,PRDX3,CDCA5,EIF2D,H2AFX,ITGB1,CBWD1,KPNA2,ANP32E,BTF3,UBE2C,CCNB2,CD81,OAZ1,ESPL1 |
| 3.736e-07 | -14.80 | GSE9988_ANTI_TREM1_VS_LPS_MONOCYTE_UP | MSigDB lists | GSE9988_ANTI_TREM1_VS_LPS_MONOCYTE_UP | 177 | 53 | 17377 | 2626 |
KCTD7,GNPDA1,PHF23,TSC22D3,HEXB,ARID5A,C5orf30,RRAGC,GGA2,ATP6V1B2,MAP1LC3B,BCAP31,CHKA,ANKRD28,MOAP1,DTL,SNUPN,SLC1A4,RNASEK,ZCCHC2,FBXO7,NAA50,BRI3,NDUFB9,AFF1,FNIP2,SLC26A2,TMBIM1,ATP6V1G1,TSHZ1,TCTEX1D2,LONRF3,MAPKAPK3,PGS1,AMD1,ACSL3,CAMSAP1,MAP4K3,SLC17A5,VKORC1,RHOB,PI4K2A,SH3BP5,SCARB2,SGSH,PEX5,CORO1C,LIMK1,WDR91,NRBP1,CSNK1D,ZC3HC1,FAM83G |
| 3.736e-07 | -14.80 | GSE22589_HEALTHY_VS_HIV_AND_SIV_INFECTED_DC_DN | MSigDB lists | GSE22589_HEALTHY_VS_HIV_AND_SIV_INFECTED_DC_DN | 177 | 53 | 17377 | 2626 |
IMMT,PPCS,MTX3,GXYLT1,NF1,PHF23,FAM53C,MAGED1,TMEM97,RAB6A,MXD4,LCLAT1,ELMOD2,COPG2,BCAP31,HMG20A,CHKA,TERF2IP,CSDE1,FAM192A,ABL2,CYHR1,PSMD2,NUS1,INPP5A,SNX18,CENPJ,PPP1R8,LTN1,RPN2,RPRD1B,SAP30L,CCAR1,CGGBP1,MAPRE2,TACC1,NOA1,OAF,MAP4K4,CDC6,UBE4B,DIDO1,TOLLIP,ABHD5,KIF18A,NRM,SLC16A1,ZDHHC7,C4orf46,ATP6V0C,NCOA1,PITRM1,ANXA11 |
| 3.736e-07 | -14.80 | GSE21927_C26GM_VS_4T1_TUMOR_MONOCYTE_BALBC_DN | MSigDB lists | GSE21927_C26GM_VS_4T1_TUMOR_MONOCYTE_BALBC_DN | 177 | 53 | 17377 | 2626 |
WASF2,CYLD,PNISR,GMFG,TSC2,MPHOSPH8,TMEM41B,NACA,ACAP1,KLF13,CCNL2,MAPK14,CCDC28A,RPL11,MAT2B,ADD3,ARHGEF1,TTC3,CNN2,POLR1B,TTC17,METTL9,MAML1,CITED2,ABI1,PABPC1,SPTAN1,ATP6V1G1,SRSF11,GCC2,PTPN18,BAZ2A,ZNF500,E2F3,FBXO9,CBFA2T2,RPL27A,MACF1,CDK11A,EIF3G,ARHGAP15,PLEKHF2,EPB41,MAN2A2,VEZF1,ZNF862,TMED10,SNAP23,TRIM52,FAM208A,IGBP1,TOB1,S100PBP |
| 3.766e-07 | -14.79 | MORF_PAPSS1 | MSigDB lists | MORF_PAPSS1 | 98 | 35 | 17377 | 2626 |
DYNLL1,SUMO2,ACTR3,STARD7,RAB6A,XPO7,AP3S1,GNB2,RAD23A,RPN1,DNAJC8,ARPC5,SEC24C,HADHB,CS,CAPZA1,TNPO3,TCEA1,NAP1L4,AHCYL1,IFRD1,SNRNP200,PPT1,VDAC2,DCTD,DDX39A,SERP1,ARF4,KRIT1,XRCC5,EPRS,LRPPRC,MDH1,HDAC2,SMNDC1 |
| 3.774e-07 | -14.79 | LY_AGING_OLD_DN | MSigDB lists | LY_AGING_OLD_DN | 55 | 24 | 17377 | 2626 |
PLK1,H2AFZ,NASP,FOXM1,CENPF,MYBL2,KIF23,KIF2C,PKMYT1,CCNF,CCNB1,MCM2,DDX39A,KIF11,HMGN2,PCNA,CCNA2,KIF14,SAFB,H2AFX,HMGB2,CDC25B,FBL,UBE2C |
| 3.774e-07 | -14.79 | MORF_BAG5 | MSigDB lists | MORF_BAG5 | 55 | 24 | 17377 | 2626 |
SP3,KARS,GMFB,JTB,ENSA,STARD7,CTCF,COX4I1,RAB11A,MBD4,PDCD6,SYNCRIP,SETD3,BANF1,RAD23B,COX7A2L,BUD31,PSMC1,COIL,MYL12B,TMED2,EEF1D,EBAG9,ATP6V1G1 |
| 3.776e-07 | -14.79 | MOOTHA_VOXPHOS | MSigDB lists | MOOTHA_VOXPHOS | 70 | 28 | 17377 | 2626 |
COX5B,NDUFA5,COX15,NDUFS1,NDUFB6,UQCR10,NDUFA4,COX4I1,CYCS,NDUFA7,BCL2L1,NDUFB1,MBD3,SDHA,NDUFS7,CYB5A,NDUFS4,SDHB,NDUFA2,NDUFB4,TONSL,COX7A2L,COX8A,COX5A,UQCRH,NDUFS8,CYC1,NDUFA3 |
| 3.776e-07 | -14.79 | DANG_REGULATED_BY_MYC_UP | MSigDB lists | DANG_REGULATED_BY_MYC_UP | 70 | 28 | 17377 | 2626 |
SEPHS2,SRM,CCNC,TDP1,TK1,FEZ2,TXN,SNRPB,TCF3,SUMO2,SLC2A1,UCK2,SNRPD3,VDAC1,SLC20A1,TXNL4A,TFRC,SRSF1,HOMER1,UAP1,ZNF330,TBL3,TFDP1,EFTUD2,SLC16A1,RUVBL2,SNRNP70,UBE2C |
| 3.795e-07 | -14.78 | Transport to the Golgi and subsequent modification | REACTOME pathways | R-HSA-948021 | 164 | 53 | 10287 | 1696 |
TMED7,COPA,GORASP1,DYNLL1,B4GALT5,COPE,DCTN2,ANK3,B4GALT1,TMED3,ARF1,B4GALT4,SEC16A,COPG2,COPB2,MAN1A1,ANKRD28,CD59,NAPG,SEC24C,ARF5,FUT8,PPP6C,TFG,ST8SIA2,LMAN1,PPP6R1,MGAT5,TMED2,KDELR1,PREB,DCTN1,SPTAN1,USO1,TRAPPC9,TMEM115,COG1,MCFD2,RAB1A,GOSR1,ARF4,SEC31A,MAN2A2,SEC23IP,GOLGA2,NSF,TMED10,MIA2,B4GALT3,PPP6R3,CSNK1D,B4GALT2,DYNC1LI2 |
| 3.818e-07 | -14.78 | GSE21063_WT_VS_NFATC1_KO_BCELL_DN | MSigDB lists | GSE21063_WT_VS_NFATC1_KO_BCELL_DN | 191 | 56 | 17377 | 2626 |
MIB2,PWWP2A,TBC1D12,CDCA3,OLA1,CHKB,TMED3,CNTROB,MAPK14,RCOR3,KTN1,LYAR,CLIC4,PSMA6,IARS,GOT2,AKR1B1,FOXN2,KNTC1,SLC35C2,PCBP2,TACC3,SMC4,MLST8,HP1BP3,METTL1,IFRD1,CYTH1,ASPM,TEX10,CKAP2L,NUSAP1,UBE4B,SMC2,UTP3,ANLN,BORA,CLNS1A,EIF3A,SOCS7,KIF2A,EPRS,NAP1L1,CDC16,PALB2,FAM110A,PSMD8,TULP3,ARNTL,WDR62,TATDN1,E2F2,UBE2C,HIPK3,SMNDC1,SSRP1 |
| 3.818e-07 | -14.78 | GSE369_PRE_VS_POST_IL6_INJECTION_SOCS3_KO_LIVER_UP | MSigDB lists | GSE369_PRE_VS_POST_IL6_INJECTION_SOCS3_KO_LIVER_UP | 191 | 56 | 17377 | 2626 |
UBE2D3,CYTIP,TXN,KLHL21,TSC22D3,RAF1,ADO,ZNF267,MAP1LC3B,SLC20A1,CHD1,CFLAR,PAPOLA,RPL23A,PRNP,ANKRD28,MOAP1,SEC11A,ABL2,RRN3,EIF2S2,IARS,RALB,RBM3,CLDND1,RP2,EIF5,SLC12A2,TMED2,CDC5L,SHOC2,IFRD1,MKLN1,KLF10,NET1,LDHA,EZR,MCL1,MCFD2,ICAM2,CHMP2B,RAB1A,KLF6,TARS,RHEB,SERTAD2,MTHFD2,ETS2,PFDN4,CEBPG,RBPJ,RUFY3,PGAM1,RNF139,EYA2,DYNC1LI2 |
| 3.818e-07 | -14.78 | GSE12392_CD8A_POS_VS_NEG_SPLEEN_DC_DN | MSigDB lists | GSE12392_CD8A_POS_VS_NEG_SPLEEN_DC_DN | 191 | 56 | 17377 | 2626 |
TMEM106C,SYS1,PRKCSH,DYNLL1,MUM1,CDT1,CENPF,CUTA,CDCA8,KIF23,STMN1,REPS1,FANCI,SPAG5,KIFC1,DPYSL2,DAPK1,KIF22,KNTC1,CDC25B,MAST2,CENPM,TTLL12,TPCN1,IMPA2,SMC4,DEAF1,PSRC1,PBK,MAP4K4,MKI67,WDHD1,RRM2,BRCA1,PKMYT1,PLEC,LY6E,VKORC1,ANLN,KRTCAP2,SHCBP1,KIF11,RFC2,TRIM28,PRIM1,HLA-B,RAD51C,KEAP1,CDCA4,PPP2R5A,SEC61A1,TXNDC16,CDCA5,NLRC5,CENPT,DMWD |
| 3.822e-07 | -14.78 | LUC7L (LUC7 like) | protein interactions | 55692 | 120 | 42 | 17029 | 2761 |
CMAS,PRPF38B,CHERP,ZCCHC8,ZFP91,SUZ12,GADD45G,CSNK2A1,JMJD6,THRAP3,SNRPD3,SRRT,YY1AP1,RBM23,CTNNBL1,PPIG,MRPS27,TNPO3,MRM3,LUC7L2,SRSF10,SRPK2,CDC5L,SRSF11,FTL,PHF10,PRRC2A,MRS2,RNPS1,BCLAF1,FXR1,LUC7L,PRDX1,SRSF1,SYNCRIP,RBM25,HNRNPR,CLK3,LUC7L3,ZRANB2,SNRNP70,PRPF4B |
| 3.822e-07 | -14.78 | Eif3a (eukaryotic translation initiation factor 3, subunit A) | protein interactions | 13669 | 120 | 42 | 17029 | 2761 |
RPS15,DDX47,RPS2,EIF3D,SND1,BRIX1,RPL11,RPL23A,LYAR,PA2G4,RPL17,RTCB,DDX31,RPL19,MRPL48,HP1BP3,PPAN,SRP72,EIF3L,PRRC2A,DHX29,NSUN2,GTPBP4,RPL8,RPL38,RPS10,RPS24,MPG,RPL27A,EIF4G2,EIF3G,RPSA,EIF3A,EIF3H,POLR2A,SUPT16H,EIF3K,RPL32,RPS14,BAZ1B,FAU,CCDC137 |
| 3.830e-07 | -14.78 | Golgi apparatus | cellular component | GO:0005794 | 1505 | 291 | 18223 | 2701 |
TMED7,RAB14,TSC2,ADAM10,ZDHHC8,AP3M2,TGOLN2,SYNRG,RIC1,ASAP2,RABGAP1L,AP1M1,DNM2,AP2B1,TFG,RHBDD2,MGAT5,PLK3,PGAP2,SGCE,USO1,RHOBTB3,TMEM115,NRAS,AATF,ATG9A,GALNT7,MCFD2,SLC50A1,RAB2B,ARF4,TMED10,LIMK1,MYO18A,VIPAS39,ST3GAL2,CHPF2,RTN3,B4GALT2,SVIP,MAPRE1,CLSPN,SCOC,GGA1,HLA-E,B4GALT1,SLC35B1,PMF1,TMED3,NOTCH2,TMEM165,PSEN1,PDXDC1,COPG2,COPB2,CD59,RNF121,TPST1,PIKFYVE,LPCAT1,PPP6R1,TMED2,NAGPA,GCC2,CPQ,MAN1B1,GTPBP4,USF3,MFNG,ITM2A,GORASP2,GOSR1,MAP2K2,PI4K2A,SEC31A,CAT,SCARB2,OSBPL11,GOLGA2,NSF,ERGIC3,USP32,ARAP1,VCPIP1,SAMD8,SMPD4,PPP6R3,EXOC3,SYS1,TRIP10,RAF1,GPR89A,ANK3,RAC1,VTI1A,SLC39A13,RXYLT1,SLC35B2,AP1B1,APP,RAB21,TBC1D14,NSFL1C,GCC1,TMBIM1,GOPC,CUL3,ATP6V0A1,GORAB,PKMYT1,RAB1A,AP4E1,ERC1,PEX5,GOLGA8A,CAMKMT,ATF6,B4GALT3,CSNK1D,TMBIM4,B4GALT5,AGPAT3,IFT27,RAB11A,HEATR5B,HLA-A,GOLM1,CAPN2,PDCD10,ARF5,FUT8,SLC38A10,ST8SIA2,MSH6,LYPLA2,MOB4,PACS1,PDE3B,MACF1,PICALM,SPPL2B,SH3GLB1,YIF1A,NUCB1,WNT5B,DBI,STX18,FAM3C,GPR89B,SNAPIN,COPA,AGRN,ALKBH5,CDIPT,BECN1,SEC16A,PRNP,RAB8A,CDC42,AP3S2,RAB35,IMPAD1,PHTF1,RP2,SLC35C2,DRAM2,APH1A,LAP3,LRBA,PSMG1,PITPNB,STX16,RHEB,OPTN,MAN2A2,CHEK2,GALNT10,ROCK1,CLU,CLN3,CHPT1,NAA60,LZTR1,GORASP1,TM9SF4,AGTRAP,SDC2,CIB1,PCSK7,CDK13,RAB6A,B4GALT4,QSOX2,C1GALT1,PPIL2,EI24,KIFAP3,PREB,KDELR1,CYTH1,TRAPPC9,ACSL3,ZDHHC3,NMT2,CAND1,GALNT2,GOLGA4,ZDHHC7,ECPAS,GLT8D1,SART1,CORO7,ASH1L,GNPNAT1,COPE,SLC2A1,CLCC1,LYN,EXT2,BCAP31,CSDE1,ANKRD28,UBXN2A,WDR44,SAR1A,AKAP8,PPP6C,CLTB,LMAN1,F2R,SCYL3,CHP1,MOSPD1,EBAG9,CLCN3,PPT1,RAB7A,DCLRE1C,BICD2,PEF1,ATP1A1,SURF4,SCAP,UBXN2B,AP1S1,CANT1,MAPK1,CHID1,ABCA1,GOLIM4,GOLPH3L,SRGN,SCYL1,VPS45,ARFIP2,CHIC2,ARF1,GGA2,AP3S1,SCYL2,XPR1,MAN1A1,FGFR3,KLHL20,SEC24C,ZDHHC13,SLC35B4,ARHGEF2,YIF1B,DDX31,SLC35A1,MYO5A,B3GALT6,TGFB1,ZDHHC18,ATP2C1,RFFL,COG1,WDR81,PNPLA8,MAPK3,HLA-B,RAB18,SEC23IP,PDCD6,GOLGA7,SNAP29,GLG1,PLOD3,PREPL,HRAS |
| 3.834e-07 | -14.77 | INO80B (INO80 complex subunit B) | protein interactions | 83444 | 100 | 37 | 17029 | 2761 |
PRPF38B,RPS2,RPLP2,ZNF768,DHX9,KIF23,INO80E,WDR5,CHD1,RPL11,RPL23A,FBXO3,RPL17,UCHL5,RPL19,FTSJ3,LUC7L2,PRPF19,SRPK2,SRSF11,BRD4,RPL8,RPL6,SREK1,MAP7D1,LUC7L,RPL27A,DHX15,POLR2A,DDX17,BRD2,ODF2,BCL7C,DDX5,RUVBL2,YY1,CD81 |
| 3.834e-07 | -14.77 | TPI1 (triosephosphate isomerase 1) | protein interactions | 7167 | 100 | 37 | 17029 | 2761 |
NDUFV2,PDCD6IP,EWSR1,SUZ12,TKT,CUL1,NIT2,SDHA,APP,PARK7,NDUFV1,PCNA,UCHL5,AKR1B1,TARDBP,PDIA6,ATF2,GPD1L,CFL1,LDHB,DDX24,LDHA,ADSL,BRCA1,VDAC1,MCM2,SEC23IP,HNRNPR,MAPK6,ANP32E,PDXK,GPI,CDK2,PGAM1,TERF1,POT1,CDKN2A |
| 3.850e-07 | -14.77 | SRP14 (signal recognition particle 14) | protein interactions | 6727 | 77 | 31 | 17029 | 2761 |
SRP72,LARS,NIFK,CYLD,PRKDC,RPL6,CUL3,CUL1,SEPT7,PKM,MCM2,GAR1,PHF6,NPLOC4,CAND1,EEF2K,LYAR,DDX56,EIF4A3,HUWE1,ZNF746,WDR4,NSFL1C,ANP32A,RPL19,DDX5,PDLIM5,PDCD2L,SZRD1,CDC5L,PRPF19 |
| 3.850e-07 | -14.77 | CHAF1A (chromatin assembly factor 1 subunit A) | protein interactions | 10036 | 77 | 31 | 17029 | 2761 |
MBD1,LZTR1,EWSR1,PRKDC,SUMO2,DBF4,ELOA,NUSAP1,BLM,BECN1,RPS9,TRIM28,ASF1B,CHAF1A,RPA1,XRCC5,CBX3,PAF1,PCNA,ANP32A,HMGB2,YWHAZ,RBM3,CNOT6,H3F3A,CNOT6L,RBBP4,CDK2,TOB1,PABPC1,MSH6 |
| 3.861e-07 | -14.77 | GSE29617_CTRL_VS_DAY3_TIV_FLU_VACCINE_PBMC_2008_UP | MSigDB lists | GSE29617_CTRL_VS_DAY3_TIV_FLU_VACCINE_PBMC_2008_UP | 168 | 51 | 17377 | 2626 |
FAM208B,CYLD,MTX3,TMEM41B,GNE,ARID5A,AP3M2,SAFB2,PPP1R16B,QSOX2,RGS1,RNF103,ZNF92,SIAH1,TIMM23,AKAP8,RAD23B,DCP1A,ZFYVE27,NUP153,ILKAP,PCBP2,PLK3,YTHDC1,SNRNP200,DDX24,COQ10B,BTG2,USP42,TUBGCP5,ILF3,SREK1,BCLAF1,RANGAP1,MEF2D,KDM3A,SPPL2B,EML4,DHX15,USP36,EPB41,DDX17,LEMD2,GOLGA4,RBM25,L3MBTL3,ARNTL,UHRF2,SMAD4,DYNC1LI2,DDX52 |
| 3.861e-07 | -14.77 | GSE3920_IFNB_VS_IFNG_TREATED_ENDOTHELIAL_CELL_DN | MSigDB lists | GSE3920_IFNB_VS_IFNG_TREATED_ENDOTHELIAL_CELL_DN | 168 | 51 | 17377 | 2626 |
SEPHS2,NCOR2,GMFG,ADD1,CENPF,VPS45,RACGAP1,SIKE1,SDF2L1,UBQLN2,SYNRG,CUTC,SDHA,CMTM6,POLR3K,CPNE3,ATPAF1,UBLCP1,NUP210,ZNRF2,SLC35B4,PRC1,GLTP,CDC25B,HP1BP3,UBQLN4,DHX29,MBLAC2,PBK,PPP1R21,EHMT1,CYP20A1,NUP155,GALK2,LRRC1,MCM2,MEN1,UBTF,JAK1,TXNDC16,CERS6,DHX16,ACLY,ITGB1,CCDC69,PRMT7,ACAT1,ATP6V1C1,TAF6,CHID1,DDB1 |
| 3.871e-07 | -14.76 | KAMMINGA_EZH2_TARGETS | MSigDB lists | KAMMINGA_EZH2_TARGETS | 41 | 20 | 17377 | 2626 |
H2AFZ,DBF4,MKI67,RRM1,NUSAP1,AURKB,SMC2,MCM2,PRIM1,NAP1L1,PCNA,RBL1,CDCA5,TFDP1,PRC1,AHCY,KPNA2,CCNB2,TACC3,SMC4 |
| 3.912e-07 | -14.75 | CRBN (cereblon) | protein interactions | 51185 | 112 | 40 | 17029 | 2761 |
TXN,HNRNPAB,IVNS1ABP,ZFP91,PRKAA1,AGO2,GLUD1,ATP5F1B,SNRPD3,CSNK1A1,HNRNPA2B1,SPINDOC,RTCB,PDIA6,LUC7L2,HNRNPM,COPS8,SRSF11,RPL35,RBX1,SNRPB,BRCA1,PCGF1,KIF11,CCT8,MATR3,RPSA,CLNS1A,RBMX,STK38,PRPS2,APPL2,SLC16A1,DDX5,ATP5F1A,RUVBL2,SRSF3,FUS,COPS6,DDB1 |
| 3.924e-07 | -14.75 | PAIP1 (poly(A) binding protein interacting protein 1) | protein interactions | 10605 | 42 | 21 | 17029 | 2761 |
RPS15,GSPT2,CUL3,SREK1,ADSL,EIF3G,EIF3A,PAIP2,CAND1,WWP2,CSDE1,SYNCRIP,RBMX,PPM1G,H2AFX,UPF2,HNRNPDL,PABPC1,FTSJ3,PDCD4,LUC7L2 |
| 3.930e-07 | -14.75 | GSE40274_CTRL_VS_LEF1_TRANSDUCED_ACTIVATED_CD4_TCELL_DN | MSigDB lists | GSE40274_CTRL_VS_LEF1_TRANSDUCED_ACTIVATED_CD4_TCELL_DN | 159 | 49 | 17377 | 2626 |
SEPHS2,ZBED3,BCCIP,CTU2,KARS,RPS2,NQO1,TMEM41B,HMGN3,TUBGCP2,RSAD1,IRF4,PDXP,NUS1,SAR1A,CD3EAP,LRRC8D,BTF3L4,GTSE1,NDUFS8,MAST2,CYC1,ECD,SYTL3,PDCL3,COPS8,PLK3,RFC3,TRAFD1,HPDL,SMU1,JTB,MRPL16,LSG1,MATR3,SRSF1,TPD52L2,MRPL2,ATP1A1,SCAP,TULP3,TBL3,PTPDC1,SPRYD4,DVL1,MRPL3,VPS29,GCSH,ZC3HC1 |
| 3.973e-07 | -14.74 | GO_NEGATIVE_REGULATION_OF_ORGANELLE_ORGANIZATION | MSigDB lists | GO_NEGATIVE_REGULATION_OF_ORGANELLE_ORGANIZATION | 368 | 92 | 17377 | 2626 |
WASF2,ZNF207,CHMP2A,ANKRD27,FEZ2,ADD1,KDM4A,PTTG1,XIAP,TPX2,MYH9,CSNK2A1,BCL2L1,CCNB1,TWF2,STMN1,BIRC2,TERF2IP,KIFC1,NEK6,NOC2L,PARL,CORO1A,CEP63,DNMT1,PLK1,PPIF,ERCC1,UBQLN4,BIRC3,TUBGCP5,GMFB,EZR,AURKB,BRCA1,CCNF,SLC25A5,KIF2A,MID1IP1,CHMP4A,CHD3,MAP4,CHMP4B,CHEK2,ARRB2,CSNK1D,TUBB,KIF3B,MAPRE1,GMFG,TRIP12,PHF23,MECP2,CENPF,DCTN2,CIB1,KIF23,RACGAP1,HAUS4,RAB11A,TUBGCP2,HAUS2,MAD2L2,SPAG5,LMNA,FBXO5,STARD9,SMC3,MSH2,PRC1,CAPZA1,ARHGEF2,H2AFY,TERF2,SPTAN1,RHOA,ASPM,NEK7,MYBL2,CAPZA2,KIF11,KDM3A,HAUS8,XRCC5,ATAD2,GOLGA2,BIRC5,PML,ARAP1,WDR62,TERF1,ESPL1 |
| 3.976e-07 | -14.74 | ALYREF (Aly/REF export factor) | protein interactions | 10189 | 145 | 48 | 17029 | 2761 |
COX15,CYLD,EWSR1,TRIP12,NOP2,THOC1,SUZ12,RBM8A,DHX9,OLA1,CUL1,CHCHD2,UBE2I,SCYL2,SRRT,PARK7,PABPC4,LMNA,EIF4A3,RBM34,UBA5,EFTUD2,YBX1,RBM15,PABPC1,FGFR1OP2,HNRNPM,RBM15B,STAU1,CUL3,LSM8,BCLAF1,PRPF3,DDX39A,MATR3,SRSF1,DOT1L,CAND1,NAP1L1,RPL32,LSM6,H2AFX,PRPF4,FAU,CDK2,ARRB2,CD81,SMAD4 |
| 4.030e-07 | -14.72 | GSE6259_DEC205_POS_DC_VS_CD4_TCELL_DN | MSigDB lists | GSE6259_DEC205_POS_DC_VS_CD4_TCELL_DN | 182 | 54 | 17377 | 2626 |
HIVEP3,TOMM20,CHERP,RAB11B,PRKCSH,ANKH,NUP54,MED13L,USP39,NKRF,CDK13,PMF1,AP1B1,SYNRG,RNF103,PIP5K1C,LRRC14,DDRGK1,LYAR,TFAP4,PPIG,RAB35,RBM34,BDH1,EXOSC1,ARHGEF1,GLE1,MAP3K14,CCAR1,ZFP64,TACC1,CIC,TUFM,RFFL,WDR82,NUP155,MCM2,EIF3G,MAP2K2,RBM38,RPL36,DTWD1,SH3BP5,ANKRD10,FBXO41,CCDC86,TTC13,NRM,MAPK6,PPM1G,SCARB1,VPS4A,LONP2,GPATCH4 |
| 4.030e-07 | -14.72 | GSE24210_RESTING_TREG_VS_TCONV_DN | MSigDB lists | GSE24210_RESTING_TREG_VS_TCONV_DN | 182 | 54 | 17377 | 2626 |
SRM,HIVEP3,NQO1,NOP2,NDUFAF2,PHB2,PHF23,ZNF768,PTTG1,OLA1,XPO7,BZW2,PSMA6,EIF2S2,EIF4A3,CWC27,CD3EAP,AHSA1,AKR1B1,SEPT11,YIF1B,YBX1,DDX31,PCYT2,NAP1L4,SLC25A1,TXNL1,COPS8,CCT2,AKT2,OAF,PSMG1,NDUFA7,TMEM147,MBD3,API5,MAK16,ZDHHC3,PRDX1,GEMIN5,PPP2CA,TMEM41A,HINT1,LSM6,CHCHD1,ZNF689,ZRANB2,RUVBL2,SMPD4,NAA20,MRPL13,LRP8,GCSH,BYSL |
| 4.030e-07 | -14.72 | GSE46606_IRF4HIGH_VS_IRF4MID_CD40L_IL2_IL5_DAY3_STIMULATED_BCELL_UP | MSigDB lists | GSE46606_IRF4HIGH_VS_IRF4MID_CD40L_IL2_IL5_DAY3_STIMULATED_BCELL_UP | 182 | 54 | 17377 | 2626 |
ZNF496,RRP15,GXYLT1,CASP6,PHF23,ALKBH5,B4GALT1,GGA2,WDR5,MAPK14,RRP36,DDRGK1,RPL23A,ATP2A2,UTP18,TBC1D14,BUD31,PPP1R12C,PDCD2,ORAI1,BRI3,CNN2,GEMIN4,TECR,METTL9,CLTB,ZRANB1,CTDSP2,LDHB,MAPRE2,PTPN18,NXT1,GUK1,KLF10,PPT1,HPDL,TSPYL4,ERLIN1,PCGF6,ADSL,BUD13,MCM2,LUC7L,ARSK,TOLLIP,TSR2,DERL1,VPS26B,CORO1C,DNAJC17,IDH3B,SLC25A39,COIL,PDCD4 |
| 4.053e-07 | -14.72 | REACTOME_METABOLISM_OF_NON_CODING_RNA | MSigDB lists | REACTOME_METABOLISM_OF_NON_CODING_RNA | 48 | 22 | 17377 | 2626 |
NUP188,RAE1,SNRPB,NUP54,DDX20,NUP155,SNRPD3,NUP205,CLNS1A,GEMIN5,NUP210,SNUPN,NUP107,GEMIN6,NUP62,NUP153,GEMIN4,SNRPG,NUP85,SEH1L,AAAS,GEMIN7 |
| 4.062e-07 | -14.72 | GSE24634_NAIVE_CD4_TCELL_VS_DAY10_IL4_CONV_TREG_DN | MSigDB lists | GSE24634_NAIVE_CD4_TCELL_VS_DAY10_IL4_CONV_TREG_DN | 196 | 57 | 17377 | 2626 |
WSB2,GCLM,IMMT,PTTG1,DCTN2,TRAK1,TPX2,TMEM97,STARD7,KIF2C,BLM,RAB11A,REEP5,POLR3K,MYL6B,HLA-A,CFLAR,PA2G4,POP7,PPP4R1,DAPK1,PRC1,ANXA5,TALDO1,PDIA6,GM2A,ALDH9A1,SMC4,ACSL5,TK1,MLEC,RFC3,MAPKAPK3,ASPM,RRM2,NUSAP1,GORASP2,C9orf40,FANCE,TARS,ABHD5,KEAP1,CHMP4A,ATP6V1D,PPP2R5A,PRDX3,ACOX1,ACAT1,NUP62,PIEZO1,PDXK,RBPJ,ZMIZ1,ATP6V1C1,CCNB2,TSPAN5,TUBB |
| 4.068e-07 | -14.72 | DUSP6 (dual specificity phosphatase 6) | protein interactions | 1848 | 59 | 26 | 17029 | 2761 |
SRM,GLT8D1,TIMMDC1,MBLAC2,UBXN1,TMEM97,TIMM21,COX4I1,AURKB,AP3S1,MAPK14,RAB5B,PARK7,WRB,HDDC2,MAPK3,CAND1,ARF5,PIN1,SLC25A19,VPS4A,CYBC1,APOOL,MAPK1,FDFT1,CHP1 |
| 4.069e-07 | -14.71 | positive regulation of metabolic process | biological process | GO:0009893 | 3331 | 600 | 17256 | 2622 |
TSC2,MAP3K7CL,HEXB,AGPAT1,XIAP,CCNL2,PPP1R16B,EDRF1,FBXO22,CDK5,CALM2,USF1,DNM2,FNIP2,ECD,ZNRD1,TIPARP,SENP1,MLST8,BAK1,PLK3,ERCC1,AATF,GABPA,TOPORS,DCUN1D5,SLC50A1,ARF4,STOML2,BRMS1,MID1IP1,SMAD2,RPS27A,AXIN1,OGT,MLYCD,RNASEL,TFDP2,SMAD1,E2F2,OAZ1,HIVEP3,CLSPN,GGA1,PHF23,DHX9,EZH1,EIF2AK4,PSMD9,PARN,CDC73,LMNA,DDRGK1,TFAP4,FBXO7,FOXN2,MYDGF,NUP85,PABPC1,PHKG2,NSUN4,FOXK1,RB1CC1,MAPKAPK3,MTA2,MYBL2,BCLAF1,SRSF5,ELK1,FNTA,ETS2,CSK,SETD3,RNF139,ALS2,EGLN1,RHOG,KARS,TRERF1,IVNS1ABP,ANK3,TPX2,MYH9,CREBL2,DAZAP2,PRKACA,ANKIB1,APP,SP100,MTA1,GMEB1,RNF19A,MAVS,ATF2,RBM15,CLN6,RPRD1B,ADCY7,PSRC1,POLR2L,KAT7,MAP4K4,WBP2,POLR2D,E2F3,CIRBP,PFKFB3,CDCA2,MEF2D,RAB1A,TAZ,DDX17,TAF2,PPP2CA,HIPK2,RPLP1,TICAM1,LRP8,USP13,RPS2,ZFP91,HABP4,FLOT1,ABHD14B,WDR5,ETS1,PDCD10,ITGB8,PRDM4,TPCN1,PDPK1,PPP3CA,TNFAIP3,JTB,ZP3,PICALM,KEAP1,GPS2,PITX1,PML,HMGB2,PSAP,CD81,USF2,YWHAH,THOC1,AGRN,AAMDC,GPBP1L1,PPP1R15B,FAM129A,CSNK2A1,NENF,S1PR2,BIRC2,TRIM65,FANCI,CREM,PRNP,TET3,ABL2,PCNA,GLIS2,IL6ST,ZNF639,ETV6,PIK3R2,MYBL1,MTPN,RYBP,CDC37,PLK1,SP3,EXOSC6,RBX1,MRPL12,EZR,CDC6,UBE2V1,LRP5,BRCA1,EAF2,USP21,OPTN,E2F4,SOCS4,ADAM9,ACTB,DVL1,POT1,ZNF564,FUBP1,PHB2,NKD2,LAMTOR3,CTCF,CHCHD2,CDK13,PPP3CB,RLF,ASXL2,CRLF3,ARID1B,SUB1,RB1,MLX,NUS1,TIGAR,SSBP3,ZNF746,CTR9,TIMELESS,MDFIC,RBM3,ICE2,MAML1,LRSAM1,ACSL3,LDB1,UTP15,KRAS,MAP4K3,RTF1,NFATC2IP,IRF5,PSMC4,RXRB,SYNCRIP,NLRC5,TBPL1,RUVBL2,BTBD10,RNF114,USP7,TRAF7,FOXM1,SUMO2,LYN,DUSP22,PCBP1,BCAP31,RPL11,RAD23A,NRF1,MDM2,PIN1,PDCD2,TARDBP,SPIDR,DVL2,PRPF19,TIMP2,BIRC3,POLR2G,RAB7A,BTG2,NFATC2,SRSF1,IDE,SCAP,RBL1,TIMM17A,PLGRKT,NCOA1,H3F3A,SMAD4,BCL2L12,SLC30A9,DAP,CDT1,AGO2,NKRF,HMGN3,CSNK1A1,PAGR1,SCYL2,TFRC,PTPN2,IRF4,SS18L1,PTGES3,POLR1B,RHOA,HMGN5,PRKDC,PDCD6,NEK1,TWSG1,TFE3,E2F1,PKD2,RBPJ,NR2F2,UBE2C,IFI16,H2AFZ,ZNF496,TXN,CXXC1,YTHDF3,UBE2I,CCNB1,PARK7,GLMP,NOL11,FIZ1,TRA2B,CDC25B,DNMT1,CDC5L,KLF10,AKT2,MRNIP,AURKB,USP22,CBFB,RFC2,DOT1L,MAP3K4,HHEX,SLF1,ARRB2,NMD3,HDAC2,SVIP,DDX58,HSPH1,SCOC,POLR2K,CHTF18,PRKAA1,VAV2,GADD45G,CYCS,NOTCH2,PSEN1,METTL3,WDR48,CFLAR,FKBP1A,DAPK1,MSH2,LPCAT1,GNAI2,TMED2,TERF2,SOCS5,EIF5A,PIP4K2C,KCTD20,EXOSC9,ADRB2,ARID1A,CYFIP2,FXR1,PTTG1IP,KDM3A,CCT8,MAP2K2,TWISTNB,XRCC5,FAS,DERL1,HSPBP1,SERTAD2,GOLGA2,NSF,RBMX,ACLY,CEBPG,ARAP1,PPP3R1,PIAS2,MAP3K5,YY1,CDK2,RNF14,ZC3HAV1,ATXN3,RPS6KA1,SF3B1,RAF1,EIF3D,RAC1,MAGED1,EPM2A,TERF2IP,CRKL,CCNA2,SHC1,RALB,LPIN2,ADCY9,MRPS27,CDKN1B,CDK12,ANKLE2,CCT2,BRD4,RFC3,CDC123,TAOK1,CUL3,EDF1,TRIM28,SERP1,SUPT16H,VEZF1,PPP2R5A,SAFB,STAT1,H2AFX,ATF6,BEND3,TRIM32,EYA2,ATMIN,CSNK1D,POU3F2,NCOR2,MECP2,TCF3,BABAM1,SECISBP2,BLM,FOXO3,MAD2L2,GTF2F1,WWP2,CCNK,PTEN,PTPN11,AXIN2,CARF,CREB1,MAP3K14,CNOT6L,CITED2,MSH6,NCOA2,LONRF3,KAT2A,NEK7,ILF3,RFXANK,KLF6,MARK2,SH3GLB1,POLR2A,FADD,HGS,OAZ2,TFDP1,KHSRP,DDX5,DDB1,RORB,CCNC,ZBED3,ZNF76,IER2,HNRNPAB,KMT2E,NF1,SIRT2,UBQLN2,BECN1,MAPK14,ZNF804A,RAP1A,EIF4A3,METTL14,TCEA1,ARID4A,CARM1,ELOF1,SRPK2,COPS8,DEAF1,TRIM8,NCK1,VHL,SOX4,ABHD5,UBTF,PAF1,BAZ1B,CAB39,STK11,ZNF268,CHEK2,ROCK1,CLU,PSMC1,PPP1R12A,GORASP1,CIB1,MEF2A,THRAP3,EPHX2,RHBDD1,APOPT1,DTL,NFATC3,MED10,PYURF,BCL2,YBX1,ATP5IF1,ERLIN1,GBA,EIF2A,CAND1,TSC1,NSMF,NFIL3,NUP62,ZFP90,SNRNP70,EHD4,TOB1,SMARCD1,TCF12,PRKAB1,ASH1L,IFI27L1,PLAGL2,SMARCA4,IRF3,PAIP1,USP5,HNRNPA2B1,RRN3,BABAM2,NVL,CD3EAP,KIF14,AKAP8,CHTOP,F2R,ABI1,HTRA2,CHP1,MOSPD1,POU2AF1,EDEM2,TOLLIP,PEF1,RPS9,TAB2,HNRNPR,STAT6,ARNTL,GADD45B,SCARB1,AKNA,SMURF1,MAPK1,NAT14,MIF,DNAJC2,EYA1,DBF4,KLF13,PAWR,DCUN1D4,PIP4K2A,FBXO5,FASTKD3,FGFR3,TANK,NABP2,BRD7,ARHGEF2,H2AFY,ATG13,STAT3,TGFB1,ELOVL5,TELO2,COA3,HMGN1,ADAM17,DCAF6,PRKAR1B,MEN1,PRMT2,SYMPK,TFEB,HSPA1B,MFN2,MAPK3,CNOT9,UPF1,ATAD2,OSBPL8,KMT2B,ZMIZ1,SLF2,HRAS |
| 4.073e-07 | -14.71 | LEE_METASTASIS_AND_RNA_PROCESSING_UP | MSigDB lists | LEE_METASTASIS_AND_RNA_PROCESSING_UP | 17 | 12 | 17377 | 2626 |
GEMIN5,HNRNPA2B1,PA2G4,DHX16,GRSF1,PPIG,RAE1,SLBP,FBL,COIL,PABPC1,CSTF1 |
| 4.098e-07 | -14.71 | negative regulation of mitotic cell cycle | biological process | GO:0045930 | 311 | 81 | 17256 | 2622 |
ZNF207,HECA,GPR132,PTTG1,CUL1,BCL2L1,CCNB1,FANCI,PSMA6,PCNA,PSMD1,MDM2,NABP1,CDKN1B,ATF2,CTDSP2,CARM1,PLK1,PLK3,TIMP2,RBX1,PSMA8,BTG2,TAOK1,PSMB7,MRNIP,AURKB,BRCA1,SOX4,PSMB9,RPS27A,RBL1,PSMD8,PSMD3,E2F4,CHEK2,VPS4A,TFDP2,PSMC1,CLSPN,CDT1,CDK2AP2,CENPF,TOP2B,BLM,CNOT11,PSMD9,CDC73,MAD2L2,CNOT3,RPA2,RFWD3,RB1,PSMD2,PTEN,CENPJ,FBXO7,NABP2,MSH2,BRD7,GTSE1,BCL2,FBXL7,KNTC1,CNOT6L,MCPH1,TGFB1,PRKDC,PSMA1,PRMT2,PSMB3,PSMC4,CNOT9,TFDP1,PML,E2F1,CNOT6,PKD2,ZNF830,CDK2,HRAS |
| 4.205e-07 | -14.68 | GSE14000_UNSTIM_VS_16H_LPS_DC_UP | MSigDB lists | GSE14000_UNSTIM_VS_16H_LPS_DC_UP | 173 | 52 | 17377 | 2626 |
ST13,NDUFB6,UQCR10,CUTA,VPS45,HAUS4,SLC25A44,SLC12A9,GIT2,TUBGCP2,PABPC4,C12orf10,INPP5A,RAB4A,RPL19,TTC3,CYB5R1,SLC26A2,PRADC1,TMEM14C,MOSPD1,RPL29,SEPT9,MAPKAPK3,EMB,KIAA0930,JTB,TUFM,LRRC8A,ATXN1,USP22,ESYT1,MPG,NDUFB1,RPL27A,NDRG3,STYXL1,ZMYM3,DTWD1,EIF3K,IDE,ITPRIPL1,CCDC86,TMED10,QARS,UQCRH,NCLN,SPCS3,SCARB1,PREPL,PTDSS1,ZMAT3 |
| 4.208e-07 | -14.68 | POU5F1 (POU class 5 homeobox 1) | protein interactions | 5460 | 321 | 87 | 17029 | 2761 |
POLA2,USP7,NDUFA5,DDX47,MAX,TXN,COPA,TRAF7,TSC2,MRPS15,SUZ12,EIF3D,GLUD1,KCMF1,RBM4,FANCI,DNAAF2,RAD23B,PPP6C,TRA2B,CDC5L,USP34,RPL29,KAT7,RPL38,DDX20,PRPF3,PBRM1,MBD3,ERC1,TRIM28,SUGP1,PSMD3,TPP2,KPNA2,SASS6,SINHCAF,TUBB,PPIB,NCOR2,MRPL9,C19orf53,EWSR1,PDAP1,TOR3A,TRMT6,TIA1,LETMD1,NDUFA4,PDCD7,WDR5,ARID1B,NDUFS7,WWP2,RBM17,PSMD2,SMC3,HUWE1,RTCB,NAA50,YBX1,MSH6,SMC4,STAU1,DDX28,RPRD1A,DDX24,DHX29,PRKDC,USP42,MRPS10,MAP7D1,PCGF1,API5,ABCF1,UPF1,ETS2,NSF,PRDX3,HMGB2,ATP5F1A,SRSF3,NR2F2,ECPAS,PURA,ANAPC4,DDB1 |
| 4.212e-07 | -14.68 | purine ribonucleoside monophosphate metabolic process | biological process | GO:0009167 | 233 | 65 | 17256 | 2622 |
COX15,NDUFA5,NDUFB6,UQCR10,OLA1,ADPGK,ATP6V1B2,ATP5PF,SDHA,NDUFB9,ATP6V0A1,OGDH,NDUFA7,NDUFB1,TAZ,STOML2,NDUFA11,COX5A,DHTKD1,UQCRH,NUDT11,PFKP,NDUFV2,COX5B,GALK1,NDUFS1,MECP2,NDUFA4,CYCS,COX4I1,ATP5F1B,NDUFS7,NDUFS4,GART,NDUFV1,NDUFA2,NDUFB4,ATIC,MSH2,ATP6V0A2,NDUFS8,CYC1,NDUFA3,TGFB1,AMPD2,GUK1,NUDT4,LDHA,ADSL,ATP5MF,PKM,HSPA1B,ADSS,ATP5MC3,PARG,COX7A2L,PRPS2,COX8A,IMPDH1,ATP5F1A,GPI,NDUFS5,PGAM1,NIPSNAP2,NUDT3 |
| 4.228e-07 | -14.68 | MORF_PSMC2 | MSigDB lists | MORF_PSMC2 | 111 | 38 | 17377 | 2626 |
KARS,HNRNPAB,SEC61G,RAE1,RAC1,ENSA,COX4I1,RAB11A,BCAP31,COPB2,MBD4,ARF5,BANF1,RAD23B,XPA,BUD31,EIF5,TMED2,EBAG9,SP3,SEC61B,DPM1,GMFB,PITPNB,RAB1A,EIF4H,KIF2A,PDCD6,COX7A2L,PGRMC1,GLG1,COX5A,DUSP11,CLN3,PSMC1,MYL12B,COIL,FUBP1 |
| 4.239e-07 | -14.67 | GSE10500_ARTHRITIC_SYNOVIAL_FLUID_VS_HEALTHY_MACROPHAGE_UP | MSigDB lists | GSE10500_ARTHRITIC_SYNOVIAL_FLUID_VS_HEALTHY_MACROPHAGE_UP | 137 | 44 | 17377 | 2626 |
CERK,NUP54,RRM1,NDUFA4,LANCL1,STMN1,LYRM2,ABHD14A,MXD1,SPAG5,RPL11,RTKN,FAM192A,DAD1,POP7,SUCLG2,ANAPC7,GPD1L,EEF1D,S100A6,PGAP2,CLPTM1,KLF10,RAB7A,SLBP,PSMB9,H2AFV,SHCBP1,KIF11,TXNL4A,PSMB3,NSA2,EIF3K,SDHB,MAGED2,ITPRIPL1,TIMM17A,RPLP1,COX5A,UQCRH,FAU,PGAM1,BRD9,AP2S1 |
| 4.262e-07 | -14.67 | HERC2 (HECT and RLD domain containing E3 ubiquitin protein ligase 2) | protein interactions | 8924 | 233 | 68 | 17029 | 2761 |
COPA,RAF1,EIF3D,COPE,KTN1,PSMD1,CDC42,UCHL5,NUP153,MAVS,SENP1,RYBP,MIOS,VDAC2,LACTB,AURKB,BRCA1,DNAJA1,BICD2,RAB5B,EIF3G,EIF3A,EIF3H,EIF3K,HPS5,WDR59,STK11,CHMP4B,PSMC1,SLC30A9,UBE2D3,CLSPN,HLA-E,ASAH1,MYO9B,COPG2,LMNA,COPB2,HLA-A,HERC3,CEP104,SMC3,CCP110,XPA,TANK,SLC27A4,GTSE1,ZRANB1,PHKG2,FDFT1,FTL,GCC2,EIF3L,MLEC,ASPM,USP42,TEX10,MARK2,RPA1,GNAS,MTMR3,PCM1,SEC23IP,MAPK6,USP20,WDR62,SSSCA1,SNAPIN |
| 4.321e-07 | -14.65 | GSE12845_IGD_NEG_BLOOD_VS_PRE_GC_TONSIL_BCELL_DN | MSigDB lists | GSE12845_IGD_NEG_BLOOD_VS_PRE_GC_TONSIL_BCELL_DN | 187 | 55 | 17377 | 2626 |
FGFR1OP,UBN1,C1orf112,OLA1,RRM1,KIF23,SMARCA4,RACGAP1,SIKE1,CCNB1,IL21R,HAUS2,KTN1,CREM,FBXO5,NFATC3,BANF1,TIMELESS,H2AFY,YBX1,AHCY,POLR1B,PPP6R1,MSH6,CGGBP1,TACC3,GINS1,UBQLN4,NASP,TNFAIP3,CREG1,RAD51AP1,SUGP2,DNAJC9,AURKB,SMC2,ASB13,SOX4,RAD54B,RXRB,HMGN2,GNAS,RAD51C,POLE,DSN1,CHD3,MFAP1,NEIL3,TFDP1,SIAH2,PKD2,ACTB,RGL1,PDCD11,TUBB |
| 4.321e-07 | -14.65 | GSE23321_CD8_STEM_CELL_MEMORY_VS_EFFECTOR_MEMORY_CD8_TCELL_DN | MSigDB lists | GSE23321_CD8_STEM_CELL_MEMORY_VS_EFFECTOR_MEMORY_CD8_TCELL_DN | 187 | 55 | 17377 | 2626 |
RAB14,RAC1,GNE,MYH9,KIF23,FKBP2,TUBGCP2,HERC3,DLG5,IRF4,CCNA2,EIF2S2,DPYSL2,SRSF4,PDS5B,AFF1,TCEA1,MAP3K14,KCNAB2,RYBP,ATP6V1G1,CDC37,ERCC1,PTPN18,TNFAIP3,VDAC2,JTB,ELP4,SLBP,RRM2,PSMG1,LRP5,BCLAF1,BICD2,ESYT1,PTTG1IP,SLC25A5,KIF11,KLF6,STK17B,ZFR,MAPK3,PLD3,FNTA,PSMD8,TFDP1,MAP4,ACLY,ITGB1,PGRMC1,IMPDH1,MDH1,PIEZO1,PDXK,RNF14 |
| 4.321e-07 | -14.65 | GSE24634_TEFF_VS_TCONV_DAY3_IN_CULTURE_UP | MSigDB lists | GSE24634_TEFF_VS_TCONV_DAY3_IN_CULTURE_UP | 187 | 55 | 17377 | 2626 |
TMEM106C,KIF3B,FGFR1OP,MRPL9,RWDD1,CDT1,DBF4,UCK2,TMEM97,SMC6,PTP4A3,BRIX1,STMN1,TTF1,FANCI,CFLAR,IRF4,SNRNP25,PCNA,DUT,FUT8,PRC1,SEPT11,BCL2,TTC4,CENPM,TTLL12,SMC4,PTPRK,PPAN,TK1,TSTA3,MAPKAPK3,PBK,MRPL12,KIF15,TBRG4,PSMG1,SMC2,MTX1,SHCBP1,SLC25A5,ODC1,FANCE,SUPT16H,PAF1,TIMM13,HINT1,UAP1,EIF2D,CCNB2,UBE2C,ESPL1,TUBB,DDX52 |
| 4.321e-07 | -14.65 | GSE31082_DP_VS_CD8_SP_THYMOCYTE_UP | MSigDB lists | GSE31082_DP_VS_CD8_SP_THYMOCYTE_UP | 187 | 55 | 17377 | 2626 |
SLC30A9,GPR132,H2AFZ,DEPDC1,ZCCHC8,TRIM11,YTHDC2,WDTC1,RRM1,C5orf30,YTHDF3,SLC4A2,THRAP3,BLM,ETS1,HMG20A,REPS1,NPLOC4,EDC3,PAIP2,NAPG,HDAC7,DUT,RCSD1,FEM1B,RNF26,ABI1,DNAL4,MSH6,SMC4,CDC5L,CPNE1,TTPAL,PLK1,KDM3B,RB1CC1,PBK,VHL,NUDT4,PPP1R21,LDB1,EZR,NUSAP1,LRRC1,ICAM2,CYB5A,UEVLD,HNRNPR,MYO18A,MEGF9,DMWD,REEP4,BRD9,TOB1,TUBB |
| 4.321e-07 | -14.65 | GSE5589_LPS_VS_LPS_AND_IL10_STIM_IL10_KO_MACROPHAGE_45MIN_UP | MSigDB lists | GSE5589_LPS_VS_LPS_AND_IL10_STIM_IL10_KO_MACROPHAGE_45MIN_UP | 187 | 55 | 17377 | 2626 |
TMEM106C,EXOC3,MPHOSPH8,CAST,AP3M2,ZFYVE21,ABHD14B,SIRT2,GYG1,GGA2,ITGB5,MAP1LC3B,ELMOD2,RNF103,ANKRD28,ZNF449,MEGF8,TBC1D14,ZNF260,SOCS6,FNIP2,CYB5R1,LDLRAD3,CITED2,LRSAM1,ATP6V0D1,DCTN1,GCC2,PGGT1B,TSPAN31,MBLAC2,RDH10,SEPT8,ATXN1,ARHGEF12,ADRB2,MCFD2,PRKRA,MPG,FXR1,DHX57,CYB5A,ANKRD46,RAB2B,NECAP2,TPD52L2,GOLGA4,SEL1L,MPV17,NUP62,RNASEL,TMEM159,POT1,SNAPIN,PTOV1 |
| 4.321e-07 | -14.65 | GSE3982_MAST_CELL_VS_TH1_DN | MSigDB lists | GSE3982_MAST_CELL_VS_TH1_DN | 187 | 55 | 17377 | 2626 |
HIVEP3,NDUFV2,CDS2,CYLD,PPP1R2,TM9SF4,FOXM1,NF1,TPX2,ARF1,GGA2,BLM,ETS1,MYL6B,SPAG5,CFLAR,C12orf10,IRF4,SNRNP25,PA2G4,NAPG,PCNA,GMEB1,MSH2,TIMELESS,TAP2,KNTC1,LMAN1,SPTSSA,CLN6,HTRA2,HP1BP3,PLK1,TXNL1,TDP1,POLR2I,RFC3,MKLN1,IDH3A,POLR2D,EXOSC9,TOMM40,PSMB9,GINS4,OPTN,RPA1,MID1IP1,BIRC5,RBL1,PRDX3,GOLGA8A,PPM1G,FKBP5,PPP6R2,PDCD11 |
| 4.321e-07 | -14.65 | GSE22601_DOUBLE_NEGATIVE_VS_CD4_SINGLE_POSITIVE_THYMOCYTE_DN | MSigDB lists | GSE22601_DOUBLE_NEGATIVE_VS_CD4_SINGLE_POSITIVE_THYMOCYTE_DN | 187 | 55 | 17377 | 2626 |
BCCIP,ZNF207,HSPH1,UBE2E2,PPP1R12A,NOP2,SRSF6,SLC2A1,SECISBP2,SLC35B1,CCNL2,PSEN1,APP,MXD1,KRI1,CAPN2,VASP,NUS1,ATP2A2,RINL,ETV6,BUD31,EI24,AXIN2,CLDND1,PDIA6,TIPARP,STAT3,PPA1,S100A6,PDCL3,PPAN,POU2AF1,TIMM8B,GTF3C6,CIC,DHX29,MRS2,LDHA,CRNKL1,TBRG4,MCL1,DNAJA1,RAB1A,NDRG3,MAT2A,CYB5A,SLCO4A1,RAB18,IDE,FTSJ1,PITPNA,KPNA2,YWHAH,FUBP1 |
| 4.326e-07 | -14.65 | positive regulation of cellular metabolic process | biological process | GO:0031325 | 3074 | 558 | 17256 | 2622 |
TSC2,MAP3K7CL,HEXB,AGPAT1,XIAP,CCNL2,PPP1R16B,EDRF1,FBXO22,CDK5,CALM2,USF1,DNM2,FNIP2,ECD,SENP1,MLST8,BAK1,PLK3,ERCC1,AATF,GABPA,TOPORS,DCUN1D5,ARF4,STOML2,BRMS1,MID1IP1,SMAD2,RPS27A,AXIN1,OGT,MLYCD,RNASEL,TFDP2,SMAD1,E2F2,HIVEP3,CLSPN,PHF23,DHX9,EZH1,EIF2AK4,PSMD9,PARN,CDC73,DDRGK1,TFAP4,FBXO7,FOXN2,MYDGF,NUP85,PABPC1,PHKG2,NSUN4,FOXK1,RB1CC1,MAPKAPK3,MTA2,MYBL2,BCLAF1,SRSF5,ELK1,FNTA,ETS2,CSK,SETD3,RNF139,ALS2,EGLN1,RHOG,KARS,TRERF1,IVNS1ABP,TPX2,MYH9,CREBL2,DAZAP2,PRKACA,ANKIB1,APP,SP100,MTA1,GMEB1,RNF19A,MAVS,RBM15,ATF2,CLN6,RPRD1B,ADCY7,PSRC1,KAT7,MAP4K4,WBP2,POLR2D,CIRBP,E2F3,PFKFB3,CDCA2,MEF2D,RAB1A,TAZ,DDX17,TAF2,PPP2CA,HIPK2,RPLP1,TICAM1,LRP8,USP13,RPS2,ZFP91,HABP4,FLOT1,ABHD14B,WDR5,ETS1,PDCD10,PRDM4,TPCN1,PDPK1,PPP3CA,TNFAIP3,JTB,ZP3,PICALM,KEAP1,GPS2,PITX1,PML,HMGB2,PSAP,CD81,USF2,YWHAH,AGRN,THOC1,AAMDC,GPBP1L1,PPP1R15B,FAM129A,NENF,S1PR2,BIRC2,TRIM65,FANCI,CREM,PRNP,TET3,PCNA,GLIS2,IL6ST,ZNF639,ETV6,PIK3R2,MYBL1,RYBP,CDC37,PLK1,SP3,EXOSC6,RBX1,MRPL12,EZR,CDC6,UBE2V1,LRP5,BRCA1,EAF2,USP21,OPTN,E2F4,SOCS4,ADAM9,DVL1,POT1,ZNF564,PHB2,NKD2,LAMTOR3,CTCF,CHCHD2,CDK13,PPP3CB,RLF,ASXL2,CRLF3,ARID1B,SUB1,RB1,MLX,TIGAR,SSBP3,ZNF746,CTR9,TIMELESS,MDFIC,RBM3,ICE2,MAML1,LRSAM1,ACSL3,LDB1,UTP15,KRAS,MAP4K3,RTF1,NFATC2IP,IRF5,PSMC4,RXRB,NLRC5,TBPL1,RUVBL2,BTBD10,RNF114,USP7,TRAF7,FOXM1,SUMO2,LYN,DUSP22,PCBP1,BCAP31,RAD23A,NRF1,MDM2,PIN1,PDCD2,TARDBP,SPIDR,DVL2,PRPF19,TIMP2,BIRC3,POLR2G,BTG2,NFATC2,SRSF1,SCAP,RBL1,TIMM17A,PLGRKT,NCOA1,SMAD4,BCL2L12,SLC30A9,DAP,CDT1,AGO2,NKRF,HMGN3,CSNK1A1,PAGR1,SCYL2,TFRC,PTPN2,IRF4,SS18L1,PTGES3,RHOA,HMGN5,PRKDC,PDCD6,NEK1,TWSG1,TFE3,E2F1,PKD2,RBPJ,NR2F2,UBE2C,IFI16,H2AFZ,ZNF496,TXN,CXXC1,YTHDF3,UBE2I,CCNB1,PARK7,GLMP,NOL11,FIZ1,TRA2B,CDC25B,DNMT1,CDC5L,KLF10,AKT2,MRNIP,AURKB,USP22,CBFB,RFC2,DOT1L,MAP3K4,HHEX,SLF1,ARRB2,NMD3,HDAC2,SVIP,DDX58,HSPH1,SCOC,CHTF18,PRKAA1,VAV2,GADD45G,CYCS,NOTCH2,PSEN1,METTL3,WDR48,CFLAR,FKBP1A,DAPK1,MSH2,GNAI2,SOCS5,EIF5A,PIP4K2C,KCTD20,EXOSC9,ADRB2,ARID1A,CYFIP2,FXR1,PTTG1IP,KDM3A,CCT8,MAP2K2,XRCC5,FAS,DERL1,HSPBP1,SERTAD2,GOLGA2,NSF,RBMX,ACLY,ARAP1,CEBPG,PPP3R1,PIAS2,MAP3K5,YY1,CDK2,RNF14,ZC3HAV1,ATXN3,RAF1,RPS6KA1,EIF3D,RAC1,MAGED1,EPM2A,TERF2IP,CRKL,CCNA2,SHC1,RALB,LPIN2,ADCY9,MRPS27,CDKN1B,CDK12,ANKLE2,CCT2,BRD4,RFC3,CDC123,TAOK1,CUL3,EDF1,TRIM28,SERP1,SUPT16H,VEZF1,PPP2R5A,SAFB,STAT1,H2AFX,ATF6,BEND3,TRIM32,EYA2,CSNK1D,ATMIN,POU3F2,MECP2,TCF3,BABAM1,BLM,FOXO3,MAD2L2,GTF2F1,WWP2,CCNK,PTEN,PTPN11,AXIN2,CARF,CREB1,MAP3K14,CNOT6L,CITED2,MSH6,NCOA2,LONRF3,KAT2A,NEK7,ILF3,RFXANK,KLF6,MARK2,SH3GLB1,POLR2A,FADD,TFDP1,KHSRP,DDX5,RORB,CCNC,ZBED3,ZNF76,IER2,HNRNPAB,KMT2E,NF1,SIRT2,UBQLN2,BECN1,MAPK14,RAP1A,EIF4A3,METTL14,TCEA1,ARID4A,CARM1,ELOF1,COPS8,DEAF1,TRIM8,NCK1,VHL,SOX4,ABHD5,UBTF,PAF1,CAB39,STK11,ZNF268,CHEK2,ROCK1,CLU,PSMC1,PPP1R12A,GORASP1,CIB1,MEF2A,THRAP3,RHBDD1,APOPT1,NFATC3,MED10,YBX1,BCL2,ATP5IF1,ERLIN1,GBA,EIF2A,CAND1,TSC1,NSMF,NUP62,ZFP90,SNRNP70,EHD4,TOB1,SMARCD1,TCF12,ASH1L,IFI27L1,PLAGL2,SMARCA4,IRF3,PAIP1,USP5,HNRNPA2B1,RRN3,BABAM2,NVL,KIF14,AKAP8,CHTOP,F2R,ABI1,HTRA2,CHP1,MOSPD1,POU2AF1,EDEM2,TOLLIP,PEF1,RPS9,HNRNPR,TAB2,STAT6,ARNTL,GADD45B,SCARB1,AKNA,MAPK1,SMURF1,NAT14,MIF,DNAJC2,EYA1,DBF4,KLF13,PAWR,DCUN1D4,PIP4K2A,FBXO5,FASTKD3,FGFR3,TANK,NABP2,BRD7,ARHGEF2,ATG13,STAT3,TGFB1,ELOVL5,TELO2,COA3,HMGN1,ADAM17,DCAF6,PRKAR1B,MEN1,PRMT2,SYMPK,TFEB,HSPA1B,MFN2,MAPK3,CNOT9,UPF1,ATAD2,OSBPL8,KMT2B,ZMIZ1,SLF2,HRAS |
| 4.347e-07 | -14.65 | V$E2F_Q4 | MSigDB lists | V$E2F_Q4 | 220 | 62 | 17377 | 2626 |
POLA2,H2AFZ,CLSPN,ZCCHC8,RAB11B,CDT1,TRMT6,RMI2,SMC6,CTCF,STMN1,ASXL2,FBXO5,TFAP4,PCNA,SMC3,INTS7,CD3EAP,PPP1R8,FIZ1,MSH2,TRA2B,NUP153,PCYT2,MRPL40,MCMBP,DNMT1,ARID4A,YTHDC1,SP3,ZNF524,NASP,APH1A,PRKDC,ILF3,E2F3,SREK1,DNAJC9,RRM2,CDC6,NFATC2IP,PBRM1,PKMYT1,MCM2,APPL1,POLR2A,SRSF1,HMGN2,DDX17,CAND1,ATAD2,HNRNPR,RBL1,DCK,LUC7L3,ZNF367,KBTBD7,E2F1,NUP62,WDR62,SASS6,GEN1 |
| 4.364e-07 | -14.64 | GO_MIDBODY | MSigDB lists | GO_MIDBODY | 124 | 41 | 17377 | 2626 |
KIF3B,CTDP1,PKP4,CYLD,SLC2A1,CENPF,CDCA8,KIF23,RACGAP1,SIRT2,SPAG5,ERH,PDXP,CLIC4,CDC42,RALB,PIN1,KIF14,PRC1,DNM2,GNAI2,PLK1,RHOA,PSRC1,TACC1,ASPM,JTB,TOPORS,AURKB,SEPT7,SH3GLB1,CHMP4A,KEAP1,SEPT1,BIRC5,ZNF330,CEP55,NUP62,CHMP4B,VPS4A,ANXA11 |
| 4.364e-07 | -14.64 | G1/S Transition | REACTOME pathways | R-HSA-69206 | 119 | 42 | 10287 | 1696 |
POLA2,MAX,MCM10,CDT1,DBF4,CUL1,ORC1,CCNB1,PSMD9,FBXO5,RPA2,RB1,PSMD2,PCNA,PSMD1,PSMA6,CCNA2,MCM5,CDKN1B,ORC3,PRIM2,AKT2,PSMB7,PSMA1,RRM2,CDC6,MCM2,PSMB9,PSMB3,PSMC4,PRIM1,RPA1,PPP2CA,POLE,RPS27A,PSMD8,PSMD3,TFDP1,E2F1,TFDP2,CDK2,PSMC1 |
| 4.383e-07 | -14.64 | GO_VACUOLE_ORGANIZATION | MSigDB lists | GO_VACUOLE_ORGANIZATION | 155 | 48 | 17377 | 2626 |
RAB14,CHMP2A,PDCD6IP,HEXB,RAB23,ATG2B,ARF1,MAP1LC3B,PSEN1,BECN1,TMEM165,RAB11A,STAM,VPS25,ATG4A,ATG3,ATG13,CORO1A,CLN6,PACS2,NAGPA,CLCN3,ACP2,RB1CC1,ATG9A,PPT1,RAB7A,CHMP2B,RAB1A,RAB5B,RAB22A,TFEB,MFN2,TMEM127,HGS,CHMP4A,SNAP29,NAGLU,ATP6V0C,CHMP4B,VPS4A,WIPI2,CLN3,CHMP7,SNX14,ABCA1,ALS2,SNAPIN |
| 4.494e-07 | -14.62 | GO_DNA_BIOSYNTHETIC_PROCESS | MSigDB lists | GO_DNA_BIOSYNTHETIC_PROCESS | 107 | 37 | 17377 | 2626 |
POLA2,CENPF,RMI2,BLM,RMI1,MAD2L2,NPLOC4,WRNIP1,TERF2IP,LIN9,DTL,RPA2,PCNA,XRCC2,PTGES3,TERF2,RFC3,TK1,POLK,RAD51AP1,TOP3A,USP10,BRCA1,POLG2,GAR1,RFC2,ISG15,RPA1,RAD51C,POLE,PALB2,RPS27A,XRCC3,TERF1,POT1,RAD51D,POLQ |
| 4.494e-07 | -14.62 | REACTOME_SRP_DEPENDENT_COTRANSLATIONAL_PROTEIN_TARGETING_TO_MEMBRANE | MSigDB lists | REACTOME_SRP_DEPENDENT_COTRANSLATIONAL_PROTEIN_TARGETING_TO_MEMBRANE | 107 | 37 | 17377 | 2626 |
RPS15,RPS2,RPLP2,SEC61G,RPL15,RPL11,SSR1,RPL23A,SEC11A,RPN1,RPL17,RPL19,RPN2,SRP72,RPL29,RPL35,SEC61B,RPL8,RPL38,RPL6,RPS10,RPS24,SSR2,RPL27A,RPS9,RPSA,RPL36,RPL37,DDOST,RPL32,SEC61A1,RPS27A,RPS14,RPLP1,SPCS3,FAU,RPS26 |
| 4.573e-07 | -14.60 | positive regulation of RNA metabolic process | biological process | GO:0051254 | 1525 | 300 | 17256 | 2622 |
ZNF496,H2AFZ,CXXC1,HEXB,YTHDF3,CCNL2,CCNB1,EDRF1,PARK7,GLMP,USF1,NOL11,DNM2,TRA2B,ECD,SENP1,CDC5L,KLF10,AATF,GABPA,TOPORS,USP22,CBFB,ARF4,DOT1L,HHEX,SMAD2,RPS27A,AXIN1,OGT,RNASEL,TFDP2,SMAD1,E2F2,NMD3,HDAC2,DDX58,HIVEP3,HSPH1,PRKAA1,DHX9,EZH1,PSMD9,PSEN1,METTL3,CDC73,DDRGK1,TFAP4,FOXN2,MYDGF,PABPC1,NUP85,FOXK1,MTA2,MYBL2,BCLAF1,EXOSC9,ARID1A,SRSF5,ADRB2,ELK1,KDM3A,MAP2K2,SERTAD2,ETS2,SETD3,RBMX,PIAS2,PPP3R1,CEBPG,YY1,MAP3K5,RNF14,CDK2,ZC3HAV1,EGLN1,RHOG,KARS,TRERF1,IVNS1ABP,RPS6KA1,RAF1,MAGED1,CREBL2,APP,CCNA2,SHC1,SP100,GMEB1,LPIN2,MAVS,ATF2,RBM15,CDK12,RPRD1B,PSRC1,BRD4,KAT7,WBP2,E2F3,EDF1,MEF2D,TRIM28,SUPT16H,DDX17,TAF2,VEZF1,SAFB,HIPK2,STAT1,ATF6,ATMIN,POU3F2,MECP2,TCF3,HABP4,ABHD14B,WDR5,BLM,ETS1,FOXO3,MAD2L2,WWP2,GTF2F1,CCNK,PRDM4,CARF,CITED2,CNOT6L,CREB1,NCOA2,PPP3CA,KAT2A,RFXANK,ILF3,ZP3,KLF6,PICALM,FADD,POLR2A,GPS2,PITX1,TFDP1,PML,KHSRP,HMGB2,DDX5,CD81,USF2,YWHAH,RORB,CCNC,ZBED3,ZNF76,IER2,HNRNPAB,AGRN,THOC1,AAMDC,KMT2E,GPBP1L1,SIRT2,MAPK14,CREM,TET3,GLIS2,METTL14,ZNF639,ETV6,PIK3R2,TCEA1,MYBL1,ARID4A,CARM1,ELOF1,RYBP,SP3,DEAF1,NCK1,VHL,MRPL12,UBE2V1,LRP5,BRCA1,EAF2,SOX4,USP21,UBTF,PAF1,E2F4,ZNF268,CHEK2,DVL1,PSMC1,ZNF564,PPP1R12A,CHCHD2,CTCF,MEF2A,CDK13,PPP3CB,THRAP3,RLF,ASXL2,CRLF3,ARID1B,SUB1,RB1,MLX,NFATC3,MED10,SSBP3,ZNF746,CTR9,ICE2,YBX1,MDFIC,MAML1,ERLIN1,LDB1,UTP15,RTF1,NFATC2IP,EIF2A,IRF5,RXRB,CAND1,PSMC4,TBPL1,NLRC5,NUP62,ZFP90,RUVBL2,SNRNP70,TOB1,SMARCD1,TCF12,ASH1L,FOXM1,PLAGL2,SMARCA4,IRF3,PCBP1,NRF1,RRN3,PIN1,TARDBP,F2R,DVL2,PRPF19,MOSPD1,POU2AF1,POLR2G,BTG2,NFATC2,SRSF1,RBL1,HNRNPR,SCAP,STAT6,ARNTL,NCOA1,AKNA,MAPK1,SMAD4,NAT14,SLC30A9,BCL2L12,DNAJC2,EYA1,AGO2,KLF13,HMGN3,NKRF,PAGR1,IRF4,BRD7,ARHGEF2,SS18L1,STAT3,TGFB1,HMGN1,DCAF6,HMGN5,PRKDC,PRMT2,MEN1,TFEB,MAPK3,UPF1,ATAD2,TFE3,E2F1,KMT2B,PKD2,RBPJ,ZMIZ1,NR2F2,HRAS,IFI16 |
| 4.575e-07 | -14.60 | TES (testin LIM domain protein) | protein interactions | 26136 | 284 | 79 | 17029 | 2761 |
PDCD6IP,COPA,FAM207A,EBNA1BP2,SNN,SEC16A,APP,TRIM65,CCDC50,THADA,AKAP8,DNM2,AHCYL1,CLTB,RPRD1B,CFL1,DCTN1,PPP1R18,DPM1,LAP3,TOR1AIP2,DNAJA1,ANLN,TRIM28,NECAP2,PAF1,TBC1D17,GRIPAP1,CORO1C,PSMD3,MYO18A,STAT1,ANP32E,ACTB,MYL12B,TUBB,GORASP1,SCYL1,TKT,CYCS,ATP5F1B,THRAP3,CDC73,COPG2,VPS25,TFRC,ERH,VASP,HUWE1,AHSA1,MSH2,TAGLN2,NAP1L4,CNN2,ALDH18A1,RNF135,STAT3,LPCAT1,SPTAN1,TRAFD1,CSRP1,PRKDC,ACSL3,TUFM,PLEC,MACF1,MAGED2,EPRS,PLAA,PML,ARAP1,GPI,PPP6R3,CDK2,IGBP1,PDLIM5,ZC3HAV1,IPO4,SSSCA1 |
| 4.610e-07 | -14.59 | RRM_1 | pfam domains | PF00076 | 199 | 57 | 17054 | 2545 |
NIFK,EWSR1,HNRNPAB,SRSF6,RBM8A,TIA1,SAFB2,RBM4,MYEF2,PABPC4,RAVER2,HNRNPA2B1,RBM17,RBM23,GRSF1,RBM34,SRSF4,TRA2B,TARDBP,RBM3,RBM12B,RBM15,PABPC1,HNRNPM,RBM15B,SRSF10,SRSF11,RBM42,PSPC1,PPIE,NOL8,SF3B6,HNRNPF,RNPS1,CIRBP,SREK1,SRSF5,EIF4H,EIF3G,SLTM,SNRPA,RBM38,SRSF1,SYNCRIP,RBM25,RBM47,HNRNPR,RBMX,SAFB,HNRNPH3,U2SURP,DNAJC17,RBMS1,SRSF3,FUS,SNRNP70,HNRNPDL |
| 4.615e-07 | -14.59 | FAF2 (Fas associated factor family member 2) | protein interactions | 23197 | 238 | 69 | 17029 | 2761 |
TOMM20,NF1,UBR2,MAGED1,CUL1,TM9SF3,UBQLN2,OAT,AHCTF1,TIMM23,SUCLG2,TRA2B,CDKN2AIP,LARS,ATG9A,RAB7A,SLC26A6,VDAC2,CUL3,RRM2,SLC25A22,ESYT1,MCM2,STK17B,STT3A,TIMM29,SEL1L,SARAF,SMURF1,PFKP,USP13,UBXN1,COX4I1,ATP5F1B,DNAJB1,HAUS2,NPLOC4,XPR1,PSMD2,HUWE1,INTS7,VMP1,ARF5,MSH2,ARL6IP1,ORAI1,UBE3C,MRPL21,LPCAT1,NUP85,TMED2,MSH6,TIMMDC1,PRKDC,ERLIN1,ATP2C1,ABCF2,SYVN1,TOMM40,CAND1,FAS,DERL1,HLA-B,VCPIP1,ACADM,TMEM159,DDB1,FAF1,ESYT2 |
| 4.620e-07 | -14.59 | ribonucleoside triphosphate metabolic process | biological process | GO:0009199 | 224 | 63 | 17256 | 2622 |
GALK1,COX15,COX5B,NDUFA5,NDUFV2,NDUFS1,NDUFB6,UQCR10,MECP2,UCK2,RAB23,OLA1,UCK1,NDUFA4,COX4I1,CYCS,EFL1,ADPGK,ATP5F1B,ATP6V1B2,ATP5PF,SDHA,NDUFS7,NDUFS4,NDUFV1,NDUFA2,NDUFB4,CTPS1,MSH2,ATP6V0A2,NDUFB9,NDUFS8,CYC1,NDUFA3,TGFB1,RHOA,GUK1,LDHA,ATP6V0A1,OGDH,NDUFA7,NDUFB1,PKM,ATP5MF,TAZ,STOML2,HSPA1B,MBIP,ATP5MC3,PARG,COX7A2L,NDUFA11,COX8A,IMPDH1,COX5A,DHTKD1,UQCRH,NDUFS5,GPI,ATP5F1A,NIPSNAP2,PGAM1,PFKP |
| 4.698e-07 | -14.57 | ADRB2 (adrenoceptor beta 2) | protein interactions | 154 | 261 | 74 | 17029 | 2761 |
NDUFA5,IMMT,TM9SF3,OAT,PCBP1,MAPK14,MAP1LC3B,GNB2,HNRNPA2B1,CALM2,MDM2,NUP210,ATP2A2,HADHB,TARDBP,RPN2,MARCH2,PDIA6,CNNM3,PCBP2,TIMM50,VHL,IDH3A,MRPL12,HNRNPF,VDAC2,NUP155,VDAC1,SLC25A5,ARF4,PON2,ATP1A1,SEC61A1,RPLP1,ARRDC1,ARRB2,TUBB,TMEM33,TMUB1,PHB2,NDUFA4,ATP5F1B,RGS2,NPLOC4,TFRC,RPN1,PSMD2,NDUFV1,GRK2,DAD1,ALDH18A1,STAT3,GNAI2,RNF5,EEF1D,TMX1,PPP3CA,PRKDC,TUFM,ADRB2,HSPA1B,GNAS,HLA-B,RAB18,HGS,NSF,CSK,PGRMC1,LRPPRC,USP20,ATP5F1A,IDH3B,CD81,ECPAS |
| 4.708e-07 | -14.57 | SEC23A (Sec23 homolog A, coat complex II component) | protein interactions | 10484 | 89 | 34 | 17029 | 2761 |
HSPH1,EWSR1,COPA,SUMO2,CUL1,UBQLN2,XPO7,SEC16A,SP100,THADA,CENPJ,SEC24C,MSH2,GTSE1,TTLL12,S100A6,TACC3,DCTN1,CDC5L,CUL3,PSMA1,PSMG1,BRCA1,MCM2,DPYSL3,CAND1,SEC31A,HSPA4,HGS,DUS3L,LRPPRC,USP11,CDK2,FAF1 |
| 4.708e-07 | -14.57 | RPL34 (ribosomal protein L34) | protein interactions | 6164 | 89 | 34 | 17029 | 2761 |
RPS15,RPS2,MAX,CYLD,RPL15,CUL1,EBNA1BP2,APP,RPL23A,CDK5,DDX56,ZNF746,RPL19,SRPK2,RPL35,RPL8,RPL38,RPL6,MTMR6,BRCA1,MCM2,RPL27A,RPS9,DAPK3,RPSA,CAND1,RPL36,RPL32,RPS14,RPLP1,KBTBD7,RRS1,CDK2,RPS26 |
| 4.728e-07 | -14.56 | GSE25146_UNSTIM_VS_HELIOBACTER_PYLORI_LPS_STIM_AGS_CELL_UP | MSigDB lists | GSE25146_UNSTIM_VS_HELIOBACTER_PYLORI_LPS_STIM_AGS_CELL_UP | 169 | 51 | 17377 | 2626 |
POLA2,PLXNC1,IVNS1ABP,CHTF18,RAF1,SRSF6,ACAP1,RACGAP1,SLC4A2,ELMOD2,USP5,PAPOLA,CDKN2C,MDM2,MTMR4,SEC24C,TXLNA,TNPO2,FAM76B,RBM15,NAA35,PREB,PLK1,RPRD1A,MLEC,ZMYND11,ZMYM5,MAN1B1,CYP20A1,PCGF6,KIF15,WDHD1,RRM2,CKAP2L,WDR82,RTF1,BCLAF1,PRPF3,BRCA1,GALNT7,ANLN,UTP20,CDC16,ATAD2,DGCR8,PTPN7,NCLN,WDR62,SNRNP70,ESPL1,DYNC1LI2 |
| 4.733e-07 | -14.56 | SPR (sepiapterin reductase) | protein interactions | 6697 | 49 | 23 | 17029 | 2761 |
MIF,PDCD6IP,UFC1,TKT,LDHA,PRDX1,SUGP1,HINT1,NDUFA2,DUT,PSMD3,ATIC,PIN1,PRDX5,PPM1G,RAD23B,MDH1,TAGLN2,AHCYL1,LTA4H,CAMK2G,LYPLA2,FUBP1 |
| 4.745e-07 | -14.56 | UBR5 (ubiquitin protein ligase E3 component n-recognin 5) | protein interactions | 51366 | 150 | 49 | 17029 | 2761 |
UBE2D3,ZNF207,MAGED1,UBXN1,GSPT2,PMS2,CIB1,XPNPEP3,BIRC2,PAIP1,WDR48,PAIP2,ANKRD28,MOAP1,SUB1,CCP110,ZNF746,CRY2,TCEA1,PABPC1,NCOA2,PPAN,DDX28,VHL,MRS2,UTP15,CUL3,RANGAP1,AURKB,PRMT2,MAPK3,SRSF1,SUPT16H,GEMIN5,KIF2A,KPNA1,SMAD2,DSN1,XRCC3,KPNA2,NCOA1,CHEK2,ARRB2,MAPK1,IGBP1,TOB1,DDB1,ATMIN,SSRP1 |
| 4.749e-07 | -14.56 | LE_EGR2_TARGETS_UP | MSigDB lists | LE_EGR2_TARGETS_UP | 103 | 36 | 17377 | 2626 |
H2AFZ,RRM1,CDCA8,KIF23,KIF2C,CCNB1,ETS1,TCF19,BZW2,LIN9,HNRNPA2B1,CCNA2,MCM5,PRC1,KIF22,RBM3,PLK1,KLF10,PSPC1,MKI67,EZR,DNAJC9,RRM2,NUSAP1,CADM1,SMC2,KIF11,BIRC5,RBL1,CORO1C,H2AFX,KPNA2,HMGB2,SLC22A23,CCNB2,HDAC2 |
| 4.886e-07 | -14.53 | GSE24634_NAIVE_CD4_TCELL_VS_DAY5_IL4_CONV_TREG_DN | MSigDB lists | GSE24634_NAIVE_CD4_TCELL_VS_DAY5_IL4_CONV_TREG_DN | 197 | 57 | 17377 | 2626 |
IMMT,RRP15,MRPS2,CSNK2A1,CYCS,POMP,FAM136A,TMEM165,CMTM6,CDK5,NAPG,SLC31A1,DDX56,ATP6V0B,DUS4L,ATG3,PPP1R8,SIVA1,AHSA1,CAPZA1,KNTC1,SGCB,PREB,ACSL5,CCT2,ERLIN1,WDR18,GTPBP4,RABIF,DNAJC9,SLBP,PSMG1,GLO1,MRPL16,RANGAP1,BRCA1,DNAJA1,ICMT,SLC25A5,DDX39A,FANCE,GINS4,PSMC4,DERL1,EPRS,ATP6V1D,ORMDL2,TIMM17A,NEIL3,PPA2,DNAJC17,ACAT1,KHSRP,ACTB,RBPJ,ATP6V1C1,RNF14 |
| 4.886e-07 | -14.53 | WHITFIELD_CELL_CYCLE_G2_M | MSigDB lists | WHITFIELD_CELL_CYCLE_G2_M | 197 | 57 | 17377 | 2626 |
UBE2D3,ZNF207,MZT1,DEPDC1,FOXM1,POC1A,CENPF,RBM8A,TPX2,CDCA3,CTCF,B4GALT1,NUF2,KIF2C,THRAP3,DNAJB1,CNTROB,BIRC2,LMNA,SPAG5,CFLAR,ASPHD2,KIF5B,CCNA2,KIF14,ARL6IP1,GTSE1,CDC25B,CNN2,TACC3,HP1BP3,PLK1,PBK,RNPS1,MKI67,NUSAP1,ARHGDIB,RANGAP1,DNAJA1,CADM1,HERPUD2,ANLN,SHCBP1,PRPSAP1,RAD51C,CDC27,BIRC5,ODF2,CEP55,ANP32E,SRSF3,NDE1,YWHAH,CCNB2,ZC3HC1,USP13,SMARCD1 |
| 4.888e-07 | -14.53 | GSE17721_CTRL_VS_LPS_8H_BMDC_UP | MSigDB lists | GSE17721_CTRL_VS_LPS_8H_BMDC_UP | 183 | 54 | 17377 | 2626 |
TRIM41,GCLM,NAT9,MRPL42,UBN1,MANBA,ZFP91,MAGED1,MRPS26,MOGS,TM9SF3,EXT2,XPR1,ATG3,SOCS6,CAPZA1,ATP6V0A2,CDC25B,CORO1A,FAM76B,TECR,CLTB,PHKG2,TMEM14C,IMPA2,RNF5,TDP1,LARS,TK1,ERMP1,PTPN18,NUDT4,ERLIN1,IDH3A,NQO2,PBK,RPL6,RPL38,SEPT8,HTATIP2,UBE4B,ADRB2,EIF3H,NEU1,MAPK3,OSBPL11,GALNT2,MRPL55,NSF,RPS14,OAZ2,H2AFX,FAF1,NUMB |
| 4.888e-07 | -14.53 | GSE41867_DAY8_EFFECTOR_VS_DAY30_MEMORY_CD8_TCELL_LCMV_ARMSTRONG_UP | MSigDB lists | GSE41867_DAY8_EFFECTOR_VS_DAY30_MEMORY_CD8_TCELL_LCMV_ARMSTRONG_UP | 183 | 54 | 17377 | 2626 |
SEPHS2,BCCIP,CCNC,NDUFS1,URB2,ARFIP2,SIKE1,HAUS4,AGFG1,UBE2I,POFUT1,EDC3,RNF121,RAP1A,NDUFA2,MSH2,BCAP29,TTC4,ERI3,CLTB,UBE2M,MRPL32,TRIM14,NUDC,CSTF1,GUK1,CDC123,TBRG4,CCDC34,BMS1,NDUFA7,SHCBP1,TXNL4A,MBD3,MAP2K2,TMEM201,CBX3,MFN2,XRCC5,TPD52L2,MRPL55,HINT1,PSMD3,UBXN2B,EIF2D,CEP55,KHSRP,TAF12,REEP4,LRP8,ZC3HAV1,HDAC2,FAF1,DDB1 |
| 4.888e-07 | -14.53 | GSE37605_FOXP3_FUSION_GFP_VS_IRES_GFP_TREG_NOD_UP | MSigDB lists | GSE37605_FOXP3_FUSION_GFP_VS_IRES_GFP_TREG_NOD_UP | 183 | 54 | 17377 | 2626 |
TXN,AGTRAP,UFC1,RAC1,CDT1,DCTN2,TRAK1,NIT2,MYO9B,BRIX1,TCF19,PMVK,CHD1,HAUS2,HDDC2,CDKN2C,TIMM23,DAD1,ZNF639,DUT,BANF1,RRBP1,ZBTB22,AHCY,TAF5L,MRPL11,PRADC1,METTL9,IFT46,TMEM160,PRPF19,METTL1,ERCC1,TIMP2,KLF10,MRPL12,LDHA,EMP3,UTP3,CAPZA2,ADRB2,VDAC1,CBFA2T2,MPG,COMMD4,KIF2A,PDCD6,MID1IP1,BIRC5,RBMX,PGRMC1,COPS6,UBE2C,FAF1 |
| 4.888e-07 | -14.53 | GSE41867_LCMV_ARMSTRONG_VS_CLONE13_DAY8_EFFECTOR_CD8_TCELL_UP | MSigDB lists | GSE41867_LCMV_ARMSTRONG_VS_CLONE13_DAY8_EFFECTOR_CD8_TCELL_UP | 183 | 54 | 17377 | 2626 |
HIVEP3,SYS1,FOXM1,DAP,DCTN2,UROD,GYG1,DOCK11,AP3S1,PSEN1,TMEM165,FOXO3,GIT2,RNF103,PRPF18,MBD4,PAIP2,CYHR1,SLC31A1,HDAC7,RABGAP1L,SLC44A1,MRPL34,ATG13,TP53BP2,ZNF710,FAM3A,N4BP2,ARID4A,GPX4,POU2AF1,DCAF6,PSRC1,KIAA0040,PPT1,ERLIN1,BTG2,ZMYM5,TLK1,PIP4K2C,ITM2A,NSA2,RBM47,TXNDC16,ACYP1,TMED10,L3MBTL3,HNRNPH3,FAM3C,PML,SIL1,REEP4,TOB1,ESYT2 |
| 4.888e-07 | -14.53 | GSE14769_20MIN_VS_360MIN_LPS_BMDM_UP | MSigDB lists | GSE14769_20MIN_VS_360MIN_LPS_BMDM_UP | 183 | 54 | 17377 | 2626 |
SEPHS2,COMMD10,RPS2,GOLIM4,NDUFS1,GORASP1,EYA1,TMEM97,KCTD17,NDUFA4,GLUD1,CLCC1,MXD4,WDR5,SDHA,NUP205,MEAF6,EEF2K,FKBP1A,IARS,AKR1B1,ANAPC7,PRADC1,S100A6,KCNAB2,PSRC1,PTPN18,FAM118B,CDC123,NQO2,KIAA0930,CYP20A1,RTF1,ARHGDIB,POLG2,ZDHHC3,ASF1B,MKNK1,GNA12,NEIL3,WDR7,E2F1,ACAT1,MDH1,CTSA,WIPI2,OSGEPL1,SMAD1,PPP5C,IDH3B,AP2S1,TSPAN5,RAB3IL1,NXT2 |
| 4.942e-07 | -14.52 | KRR1 (KRR1, small subunit processome component homolog) | protein interactions | 11103 | 74 | 30 | 17029 | 2761 |
NOL12,PPAN,NIFK,STAU1,RPS2,EWSR1,NOP2,AATF,DDX24,SUZ12,RPL6,CUL3,UTP15,EBNA1BP2,MAK16,RPSA,RPL11,CAND1,DDX56,RPS14,RBM34,TBL3,H2AFX,RPF2,MAVS,RRS1,ZC3HAV1,IFI16,BYSL,DDX52 |
| 4.946e-07 | -14.52 | KPNA1 (karyopherin subunit alpha 1) | protein interactions | 3836 | 121 | 42 | 17029 | 2761 |
USP7,PHB2,ARID2,SF3B1,TPX2,NUP54,CUL1,SMARCA4,LMNA,PTPN2,LYAR,SUB1,MDM2,CTNNBL1,CDKN1B,ANP32A,CRY2,NUP153,FBL,STAT3,PRPF19,CDKN2AIP,DCAF6,GABPA,MTA2,GOPC,DCAF8,CUL3,SUPT20H,PKM,MCM2,MBD3,CAND1,HSPA4,CLK3,STAT1,NUP62,ANP32E,KPNA2,RUVBL2,RBBP4,HDAC2 |
| 4.962e-07 | -14.52 | RPS19 (ribosomal protein S19) | protein interactions | 6223 | 176 | 55 | 17029 | 2761 |
RPS15,RPS2,CYLD,EWSR1,NQO1,RPLP2,RPL15,CUL1,THRAP3,BLM,APP,TUBGCP2,RPL11,RPL23A,HNRNPA2B1,EIF2S2,SHC1,RPL17,HUWE1,RRBP1,RPL19,RPL35,RPS10,RPL6,CUL3,RPL8,RPL38,RPS24,KRAS,BRCA1,EIF2A,MCM2,RPL27A,SLC25A5,RPS9,RPSA,CAND1,RPL36,SUGP1,KPNA1,FNTA,RPS27A,RPS14,RPLP1,RBMS1,PRPF4,KLHDC4,RRS1,FAU,CDK2,ARRB2,SMURF1,CD81,RPS26,POT1 |
| 4.979e-07 | -14.51 | purine nucleoside monophosphate metabolic process | biological process | GO:0009126 | 234 | 65 | 17256 | 2622 |
COX15,NDUFA5,NDUFB6,UQCR10,OLA1,ADPGK,ATP6V1B2,ATP5PF,SDHA,NDUFB9,ATP6V0A1,OGDH,NDUFA7,NDUFB1,TAZ,STOML2,NDUFA11,COX5A,DHTKD1,UQCRH,NUDT11,PFKP,NDUFV2,COX5B,GALK1,NDUFS1,MECP2,NDUFA4,CYCS,COX4I1,ATP5F1B,NDUFS7,NDUFS4,GART,NDUFV1,NDUFA2,NDUFB4,ATIC,MSH2,ATP6V0A2,NDUFS8,CYC1,NDUFA3,TGFB1,AMPD2,GUK1,NUDT4,LDHA,ADSL,ATP5MF,PKM,HSPA1B,ADSS,ATP5MC3,PARG,COX7A2L,PRPS2,COX8A,IMPDH1,ATP5F1A,GPI,NDUFS5,PGAM1,NIPSNAP2,NUDT3 |
| 4.986e-07 | -14.51 | GGAANCGGAANY_UNKNOWN | MSigDB lists | GGAANCGGAANY_UNKNOWN | 99 | 35 | 17377 | 2626 |
MBD1,CHMP2A,HSPH1,PRKAB1,SEC61G,GGA1,PDAP1,UBXN1,XIAP,EPN1,EBNA1BP2,POMP,SLC25A44,SEC11A,FARSA,MED8,SEC24C,BANF1,TTC17,MRPL21,GCC2,DPM1,PGS1,MTA2,RNF25,RPL38,MRPL43,BMS1,PRPF3,EIF3H,EIF3K,ATP6V1D,SEC61A1,E2F4,RUVBL2 |
| 5.028e-07 | -14.50 | EIF4A1 (eukaryotic translation initiation factor 4A1) | protein interactions | 1973 | 97 | 36 | 17029 | 2761 |
UNK,EIF3D,CHD1L,LAGE3,CUL1,SDHA,PAIP1,WWP2,EIF4A3,HUWE1,UCHL5,RPL19,CRY2,UPF2,PABPC1,CDC5L,RPAP3,STAU1,CUL3,RPL8,ADRB2,MCM2,EIF4H,EIF4G2,EIF3A,EIF3H,RPSA,CAND1,MAPK6,H2AFX,ATP5F1A,FUS,CD81,CDK2,RPS26,PDCD4 |
| 5.037e-07 | -14.50 | regulation of protein modification by small protein conjugation or removal | biological process | GO:1903320 | 215 | 61 | 17256 | 2622 |
RPS2,TRIP12,PHF23,GORASP1,DNAJB2,UBXN1,XIAP,UBE2I,DCUN1D4,PSEN1,BIRC2,HMG20A,PARK7,MAD2L2,FANCI,WDR48,ZER1,RPL11,FBXO5,CDK5,FKBP1A,UBXN2A,PTEN,MTA1,PIN1,TANK,FEM1B,CTR9,CHP1,PLK1,BIRC3,TNFAIP3,GTPBP4,CUL3,TOPORS,DNAJA1,BRCA1,ADRB2,DCUN1D5,RAB1A,SOX4,PTTG1IP,PEF1,TOLLIP,ISG15,HSPA1B,DERL1,PDCD6,HSPBP1,PLAA,GOLGA2,GPS2,AXIN1,LIMK1,SIAH2,OGT,TICAM1,PARP10,ARRB2,UBE2C,RNF139 |
| 5.048e-07 | -14.50 | ubiquitin-like protein ligase binding | molecular function | GO:0044389 | 324 | 84 | 17224 | 2647 |
USP7,ATXN3,MPHOSPH8,KDM4A,SUMO2,CUL1,UBE2Z,CCNB1,UBE2I,PRKACA,BECN1,MAP1LC3B,STAM,RPL11,MOAP1,FANCL,PA2G4,MDM2,PSMD1,CCDC50,NEK6,RALB,PCBP2,CCT2,RBX1,CUL3,UBE2V1,BRCA1,DNAJA1,SLC25A5,TRIM28,BTBD1,SMAD2,RAD18,JAK1,RPS27A,AXIN1,STAT1,ARRDC1,ATP6V0C,ATF6,CHEK2,CLU,TRAF5,ARRB2,SLF1,TUBB,USP13,DDX58,SCAMP3,SHPRH,UBXN1,NKD2,SMC6,FZD6,NPLOC4,DDRGK1,RPA2,RB1,ZNF746,FBXO7,TANK,AXIN2,BCL2,UBE2M,ERLIN1,RFFL,ANAPC2,ISG15,POLR2A,HSPA1B,XRCC5,MFN2,DERL1,HGS,HSPBP1,PIAS2,LRPPRC,PML,YWHAZ,GPI,UBE2C,SLF2,FAF1 |
| 5.084e-07 | -14.49 | BAG3 (BCL2 associated athanogene 3) | protein interactions | 9531 | 458 | 115 | 17029 | 2761 |
PDCD6IP,ATXN3,PNISR,ST13,NQO1,AAMDC,URB2,MAGED1,UROD,COPE,OLA1,AGPAT1,STARD7,DHX8,UBE2Z,NANS,DAZAP2,SNN,TWF2,SEC16A,STMN1,ANKRD39,PAIP2,SF3B2,CRKL,TET3,ZNF428,USF1,PSMA6,ATG3,EXOSC1,RAB4A,SENP1,DVL2,SRPK2,CPNE1,TIMP2,RAB7A,LRBA,WBP2,EZR,PSMG1,WIPF1,MCL1,RAB1A,VDAC1,SLC25A5,PEF1,RPSA,RAB2B,MAP3K4,PPP2CA,ALDH3B1,HSPA4,PSMD8,PSMD3,MAP4,PPA2,PSMC1,EYA2,POT1,CAPN1,ANXA11,GALK1,RPS2,EWSR1,MAPRE1,SCAMP3,GGA1,MUM1,CDCA3,XPNPEP3,PSMD9,APOPT1,MAT2B,PTPN2,FKBP1A,PSMD2,NDUFB4,MCM5,CAPZA1,ANXA5,BCL2,MVP,PABPC1,TERF2,NASP,CSRP1,TSTA3,WDR1,PRKDC,MRPS10,GORASP2,BCLAF1,PLEC,ARPC1A,HAGH,API5,PSMB3,ISG15,NAP1L1,KEAP1,PDCD6,ELMO1,PRPS2,ACLY,CTSA,YWHAZ,GPI,PSAP,RUVBL2,NANP,YWHAH,UBE2C,TERF1 |
| 5.088e-07 | -14.49 | REACTOME_RESPIRATORY_ELECTRON_TRANSPORT_ATP_SYNTHESIS_BY_CHEMIOSMOTIC_COUPLING_AND_HEAT_PRODUCTION_BY_UNCOUPLING_PROTEINS_ | MSigDB lists | REACTOME_RESPIRATORY_ELECTRON_TRANSPORT_ATP_SYNTHESIS_BY_CHEMIOSMOTIC_COUPLING_AND_HEAT_PRODUCTION_BY_UNCOUPLING_PROTEINS_ | 67 | 27 | 17377 | 2626 |
COX5B,NDUFA5,NDUFV2,NDUFS1,NDUFB6,NDUFA4,COX4I1,CYCS,NDUFA7,NDUFB1,SDHA,NDUFS7,NDUFS4,SDHB,NDUFV1,NDUFA2,NDUFB4,NDUFA11,COX7A2L,COX8A,COX5A,NDUFB9,UQCRH,NDUFS8,NDUFS5,CYC1,NDUFA3 |
| 5.096e-07 | -14.49 | V$CETS1P54_01 | MSigDB lists | V$CETS1P54_01 | 245 | 67 | 17377 | 2626 |
DDX47,RPLP2,NF1,XAB2,CAST,MON1B,EBNA1BP2,BCL2L1,CNTROB,AP1B1,PRKACA,SHC1,PPME1,UBA5,AP1M1,DNMT1,MTPN,OGG1,CGGBP1,RLIM,PRPF19,NRAS,BAZ2A,SNRPB,LYRM1,LRP5,KRTCAP2,ARL5B,STOML2,TBC1D17,DDOST,FBXO28,RWDD4,UQCRH,ARRB2,ZBTB11,CHID1,SRSF6,ZNF768,UFC1,CTCF,EPN1,AKT1S1,HMG20A,MCTS1,FBXO3,CCP110,MED8,VMP1,SEC24C,PPIG,CTR9,LYPLA2,EIF5A,MLEC,ACP2,NASP,BTAF1,RPL6,SYVN1,DDX39A,SMAP2,FNTA,PALB2,TFE3,APPL2,MRPL3 |
| 5.116e-07 | -14.49 | PCMT1 (protein-L-isoaspartate (D-aspartate) O-methyltransferase) | protein interactions | 5110 | 113 | 40 | 17029 | 2761 |
MIF,UFC1,TKT,KLHL18,CUL1,NANS,NOTCH2,ATP6V1B2,SPR,EIF1B,SCYL2,LMNA,RAD23A,KLHL20,HUWE1,AKR1B1,COPS7B,ABI1,TERF2,LDHB,VHL,CUL3,PSMB7,RRM2,RAB3IP,BRCA1,PCGF1,MCM2,VKORC1,RMC1,CAND1,CHD3,KBTBD7,ZRANB2,KLHL42,PTPDC1,CDK2,UBE2C,TERF1,POT1 |
| 5.127e-07 | -14.48 | GSE19888_ADENOSINE_A3R_ACT_VS_A3R_ACT_WITH_A3R_INH_PRETREATMENT_IN_MAST_CELL_UP | MSigDB lists | GSE19888_ADENOSINE_A3R_ACT_VS_A3R_ACT_WITH_A3R_INH_PRETREATMENT_IN_MAST_CELL_UP | 174 | 52 | 17377 | 2626 |
FGFR1OP,CKLF,DHPS,POC1A,DBF4,TMEM97,RMI2,CHCHD2,NIT2,METTL3,VPS25,RRP36,BCAT2,SNRNP25,SNUPN,CTNNBL1,EIF4A3,NDUFB4,PPCDC,ZDHHC13,KNTC1,PRADC1,RNF26,CLN6,IMPA2,PLK1,RNASEH2C,FOPNL,NET1,ZNF512,NSDHL,RAD51AP1,LYRM1,MRPL12,HNRNPF,MTX1,CCNF,MRPS14,SNRPA,STOML2,TRIM47,SLCO4A1,CDKN2AIPNL,C1orf131,DSN1,EIF2D,E2F1,C4orf46,KPNA2,WDR76,E2F2,MYL12B |
| 5.154e-07 | -14.48 | RPS28 (ribosomal protein S28) | protein interactions | 6234 | 109 | 39 | 17029 | 2761 |
RPS15,RPS2,RPLP2,EIF3D,RPL15,CUL1,RPL11,RPL23A,HNRNPA2B1,PSMD1,RPL17,UBA5,RPL19,PABPC1,HNRNPM,EIF3L,CUL3,ILF3,RPL38,RPL6,RPS10,RPS24,NDUFA7,MCM2,SLC25A5,RPS9,RPSA,CAND1,RPL36,PSMD3,RBMX,RPS14,PQBP1,H2AFX,RRS1,FAU,CDK2,CD81,RPS26 |
| 5.155e-07 | -14.48 | LOCKWOOD_AMPLIFIED_IN_LUNG_CANCER | MSigDB lists | LOCKWOOD_AMPLIFIED_IN_LUNG_CANCER | 202 | 58 | 17377 | 2626 |
SLC12A7,MRPL9,SEC61G,DAP,RMI2,AGPAT1,KLC1,MYNN,SLC4A2,PMF1,PMVK,SDHA,GNB2,RBM4,TFRC,RAD23A,CRKL,GNS,CDK5,FASTKD3,KDM2A,SHC1,SIVA1,FJX1,MRPL11,LPCAT1,S100A6,ABCC5,METTL1,TCTEX1D2,TSTA3,ABCF2,JTB,SSR2,C14orf132,RIT1,CAPZA2,LY6E,USP21,TARS,FADD,CCDC127,CAT,MBIP,PDCD6,POLR2J,SNAP29,FASTK,TFDP1,MBD6,ATP6V1C1,COPS6,B4GALT3,YY1,TAF6,PARD3,USP13,SNAPIN |
| 5.222e-07 | -14.47 | GSE3982_MAC_VS_TH2_DN | MSigDB lists | GSE3982_MAC_VS_TH2_DN | 188 | 55 | 17377 | 2626 |
MBD1,TMEM109,DHX9,RRM1,FLOT1,KIF23,ORC1,REPS1,RPL11,KRR1,NRF1,CCNA2,AHSA1,ZDHHC13,PRC1,TRA2B,CNN2,NAA35,OGG1,NUDC,TDP1,POLR2I,BIRC3,KAT2A,TSTA3,CDC123,PGS1,TEX10,KIF15,EZR,C1orf35,NUP155,DIDO1,OTUD3,CYFIP2,CBFB,RHOT2,RFC2,ASF1B,GINS4,ANKZF1,VEZF1,DAP3,ATAD2,BIRC5,GOLGA8A,XRCC3,PPP6R2,PITRM1,CCDC59,MRPL3,CAPN1,DEF6,TUBB,DDX52 |
| 5.222e-07 | -14.47 | GSE3982_NEUTROPHIL_VS_TH2_DN | MSigDB lists | GSE3982_NEUTROPHIL_VS_TH2_DN | 188 | 55 | 17377 | 2626 |
CCNC,PTMS,NDUFA5,SRSF6,CHD1L,PTTG1,GNE,CENPF,PXMP2,GTF3A,THRAP3,LACTB2,LYRM2,BCAT2,HNRNPA2B1,DST,CTNNBL1,UTP18,CD3EAP,DNAAF2,GRSF1,BANF1,AP2B1,KIF22,TCEA1,PTGES3,MRPL40,ERI3,LMAN1,TIMM8B,HMGN1,AGGF1,ATP13A1,BIRC3,ABCF2,PPIE,KIF15,NUSAP1,RANGAP1,NUP155,BRCA1,USP22,ESYT1,ODC1,MBD3,APPL1,TTC33,MAP3K4,RPL32,TPP2,PTER,HEXA,ESPL1,HDAC2,TMEM131 |
| 5.256e-07 | -14.46 | RPL17 (ribosomal protein L17) | protein interactions | 6139 | 142 | 47 | 17029 | 2761 |
KARS,RPS15,RPS2,CYLD,MECP2,RPL15,GFM2,RPL11,RPL23A,SNUPN,EIF4A3,AHSA1,EXOSC1,RPL19,TARDBP,FBL,PABPC1,STAU1,RPL29,RPL35,RPL6,CUL3,ILF3,RPL8,RPL38,TUFM,RPS24,BRCA1,MCM2,RPL27A,RPS9,RPSA,CAND1,RPL36,NAP1L1,C1orf131,SEC61A1,RPL32,RPS27A,DGCR8,RPS14,RRS1,SMURF1,CD81,RPS26,ZC3HAV1,NUDT3 |
| 5.266e-07 | -14.46 | DAXX (death domain associated protein) | protein interactions | 1616 | 159 | 51 | 17029 | 2761 |
USP7,DNMT3A,TCF3,SUMO2,HABP4,DBF4,CSNK2A1,TOP2B,NSD3,XPO7,UBE2I,ETS1,PARK7,CFLAR,MDM2,PIN1,PHF14,CREB1,STAT3,DNMT1,CARM1,TGFB1,RFC3,PBXIP1,KAT7,MKI67,CUL3,RFC2,MACF1,GAR1,FADD,DAPK3,SUPT16H,FAS,UBTF,KPNA4,GOLGA2,HIPK2,AXIN1,CDCA7L,PML,BAZ1B,CHMP4B,MAP3K5,H3F3A,COIL,HIPK3,SMAD4,CDKN2A,HDAC2,PDCD4 |
| 5.266e-07 | -14.46 | CFL1 (cofilin 1) | protein interactions | 1072 | 159 | 51 | 17029 | 2761 |
HSPH1,CYLD,RPS6KA1,DYNLL1,MDH2,TKT,MYH9,PSEN1,PCBP1,APP,CDC73,SRXN1,WWP2,PTEN,UCHL5,MCM5,PIN1,DUT,TAGLN2,ATF2,LYPLA2,LDHB,CSRP1,WDR1,RAB7A,LDHA,ATXN1,CAPZA2,PKM,MCM2,ANLN,PRDX1,ISG15,ARF4,CAT,ATP1A1,LIMK1,PRDX5,MYO18A,MAPK6,H2AFX,YWHAZ,ACTB,FUS,ROCK1,CDK2,ARRB2,SMURF1,CD81,POT1,TERF1 |
| 5.268e-07 | -14.46 | positive regulation of organelle organization | biological process | GO:0010638 | 578 | 132 | 17256 | 2622 |
PDCD6IP,KMT2E,SIRT2,CCNB1,BECN1,PARK7,CDK5,CDC42,DNMT1,CARMIL1,MLST8,CDC37,BAK1,ERCC1,SEPT9,NCK1,AKT2,LRP5,AURKB,BRCA1,OPTN,STOML2,MAP3K4,PAF1,WAS,LIMK1,OGT,TFDP2,SLF1,POT1,C2CD5,UBE2D3,MAPRE1,PHB2,PRKAA1,KCTD17,NCKAP1,RGS2,PARN,APOPT1,JMY,SPAG5,PDXP,RB1,VASP,CCP110,ARPC5,FBXO7,CTR9,BCL2,LRSAM1,CYFIP1,ATP5IF1,WDR1,PIP4K2C,GBA,RTF1,ADRB2,SEPT7,ARPC1A,CCT8,XRCC5,TSC1,CDCA5,PPP3R1,NUP62,YWHAZ,CNOT6,RUVBL2,RHOG,POC1A,DYNLL1,ACTR3,RAC1,MIEF1,MOAP1,HNRNPA2B1,RALB,AKAP8,CDKN1B,TP53BP2,CHTOP,LMAN1,CFL1,HTRA2,DCTN1,PPIF,CCT2,PSRC1,KAT7,CUL3,WBP2,WIPF1,NUSAP1,TRIM28,USP36,SURF4,NSMCE2,MAPK1,SMURF1,SMAD4,ATMIN,MECP2,CDT1,PIP4K2A,KIF5B,HUWE1,CENPJ,NABP2,BRD7,H2AFY,ATG13,CNOT6L,TGFB1,RHOA,KAT2A,NEK7,MIER1,SH3GLB1,HSPA1B,MFN2,MAPK3,TFDP1,STX18,PML,E2F1,UBE2C,YWHAH,TERF1,SLF2,ESPL1,HRAS |
| 5.283e-07 | -14.45 | Dual incision in TC-NER | REACTOME pathways | R-HSA-6782135 | 66 | 28 | 10287 | 1696 |
USP7,ERCC1,HMGN1,RFC3,POLR2I,POLR2G,POLR2L,POLR2K,RBX1,POLK,XAB2,PPIE,POLR2D,RFC2,POLR2A,RPA1,RPA2,PCNA,POLE,POLR2J,RPS27A,XPA,TCEA1,AQR,ZNF830,GTF2H2,DDB1,PRPF19 |
| 5.318e-07 | -14.45 | MULLIGHAN_MLL_SIGNATURE_2_UP | MSigDB lists | MULLIGHAN_MLL_SIGNATURE_2_UP | 396 | 97 | 17377 | 2626 |
PTMS,PLXNC1,RPS6KA1,TOR1AIP1,HEXB,TGOLN2,SLC25A44,SAFB2,COMMD8,REPS1,GIT2,NUP210,ATG3,ADCY9,NSFL1C,PARL,BCAP29,CLTB,OGG1,ADCY7,PPIF,PPT1,AKT2,SELPLG,HTATIP2,ATXN1,FRAT2,EAF2,SLC17A5,CBFB,TOLLIP,ALDH3B1,RBM47,CHD3,ARNTL,SH3GLB2,ATP6V0C,CLN3,OAZ1,ATP6V0E1,WSB2,SEPHS2,PPP1R2,SRGN,KLC1,RAB6A,PSEN1,SRRT,NDUFS7,SAC3D1,KRI1,GNS,SNRNP25,TNS3,SLC31A1,SLC1A4,MED8,RRBP1,ZDHHC13,GTSE1,TNPO3,CNPY3,S100A6,NAGPA,ABHD2,TMEM126B,KIAA0930,PIP4K2C,RANGAP1,ADRB2,PLEC,COMMD4,MAP2K2,FADD,TFEB,MYO1F,DDX23,MFN2,CAT,GNA12,PLD3,UPF1,KPNA1,ATP6V1D,SERF2,POLR2J,GPS2,OSBPL8,CTBS,CEBPG,GLG1,COX8A,PITPNA,NUP62,CTSA,YY1,ESPL1 |
| 5.328e-07 | -14.45 | HIST1H4A (histone cluster 1 H4 family member a) | protein interactions | 8359 | 172 | 54 | 17029 | 2761 |
NCOR2,HSPH1,CYLD,H2AFZ,HJURP,KDM4A,SHPRH,CUL1,JMJD6,NSD3,XPO7,UBE2I,KMT5C,EIF4A3,UCHL5,MCM5,KMT5A,H2AFY,ANP32A,BRD4,NASP,KAT2A,BAZ2A,EID1,RBX1,KAT7,WBP2,CUL3,DNAJC9,PBRM1,MCM2,ASF1B,MAPK3,CHAF1A,SUPT16H,CBX3,CAND1,DERL1,BRD2,TONSL,PPM1G,WDR4,H2AFX,PRMT7,YWHAZ,H3F3A,RBBP4,CDK2,MAPK1,PARP10,FAF1,IPO4,HDAC2,SSRP1 |
| 5.408e-07 | -14.43 | regulation of signal transduction by p53 class mediator | biological process | GO:1901796 | 178 | 53 | 17256 | 2622 |
BCL2L12,MIF,PRKAB1,TP53RK,NOP2,PRKAA1,TPX2,RMI2,CSNK2A1,BLM,MAPK14,RMI1,MEAF6,JMY,RPL11,CDK5,RPA2,RRN3,MDM2,KMT5A,PIN1,NOC2L,RPF2,BRD7,TP53BP2,PLK3,RFC3,MTA2,EHMT1,TOP3A,RFFL,BRCA1,AURKB,PTTG1IP,RFC2,MBD3,SUPT16H,RPA1,TAF2,RPS27A,CHD3,HIPK2,PML,DDX5,STK11,CHEK2,TAF12,RRS1,RBBP4,TAF6,CDK2,HDAC2,SSRP1 |
| 5.418e-07 | -14.43 | HU_GENOTOXIC_DAMAGE_4HR | MSigDB lists | HU_GENOTOXIC_DAMAGE_4HR | 35 | 18 | 17377 | 2626 |
HMGN1,MAPRE1,TIMP2,TRAFD1,CDT1,PTTG1,UCK1,CUL1,ANLN,TCF19,NCDN,MTHFD2,SYNCRIP,H2AFX,PRC1,KIF22,KPNA2,FAM76B |
| 5.436e-07 | -14.43 | YOSHIMURA_MAPK8_TARGETS_DN | MSigDB lists | YOSHIMURA_MAPK8_TARGETS_DN | 350 | 88 | 17377 | 2626 |
MAX,NF1,MDH2,RAC1,TOR1AIP1,SMARCA4,SND1,ATP6V1B2,MAPK14,ANKIB1,APP,CMTM6,HNRNPA2B1,APLP2,CDC42,NVL,TIMM23,IL6ST,HADHB,DNM2,TRA2B,RPN2,EIF5,ARL5A,GM2A,MLST8,USO1,SEC61B,KLF10,ODC1,SERP1,ASF1B,AHNAK,SMAD2,IDE,DDOST,TMED10,TPP2,STK38,SEL1L,OGT,COX5A,SMAD1,DYNC1LI2,HSPH1,PPIB,GCLM,TCF3,SDC2,NCKAP1,TFRC,DNAJB9,TNS3,SUB1,RB1,VMP1,EFTUD2,MSH2,MRPL40,SAMD4B,PDPK1,CSNK1G2,MAPKAPK3,NUDT4,AMD1,SCFD2,PSMA1,BCLAF1,EXOSC9,KIF11,MFN2,CAT,PTPRF,NUCB1,ATP6V1D,PCM1,PLAA,MAGT1,TATDN2,DBI,CEBPG,SLC16A1,PITPNA,YWHAZ,SRSF3,PSAP,NAA20,NR2F2 |
| 5.461e-07 | -14.42 | regulation of RNA splicing | biological process | GO:0043484 | 120 | 40 | 17256 | 2622 |
SRSF6,RBM8A,HABP4,TIA1,JMJD6,THRAP3,RBM4,HNRNPA2B1,RBM17,NSRP1,SRSF4,ZNF326,TRA2B,CDK12,RBM15B,SRPK2,PRPF19,SRSF10,YTHDC1,AGGF1,RBM42,RNPS1,HNRNPF,SMU1,SREK1,SRSF5,POLR2A,RBM38,SRSF1,DDX17,AHNAK,RBM25,CLK3,FASTK,RBMX,PQBP1,DDX5,SRSF3,SNRNP70,RPS26 |
| 5.505e-07 | -14.41 | ACTR2 (ARP2 actin related protein 2 homolog) | protein interactions | 10097 | 138 | 46 | 17029 | 2761 |
WASF2,UNK,TP53RK,PPP1R12A,LUZP1,DHPS,ACTR3,MYH9,EFL1,METTL3,EEF2K,ARPC5,PPME1,CAPZA1,CORO1A,TTLL12,CLTB,RPRD1B,CFL1,PDCL3,CDC5L,METTL1,BAK1,CCT2,RPRD1A,NSUN2,CUL3,KRAS,RANGAP1,CAPZA2,ANLN,ARPC1A,CCT8,SH3GLB1,RPA1,EVC2,INF2,TPD52L2,PCM1,HSPBP1,CORO1C,MYO18A,WDR4,OGT,ACTB,FUBP1 |
| 5.524e-07 | -14.41 | GSE24972_WT_VS_IRF8_KO_SPLEEN_FOLLICULAR_BCELL_DN | MSigDB lists | GSE24972_WT_VS_IRF8_KO_SPLEEN_FOLLICULAR_BCELL_DN | 179 | 53 | 17377 | 2626 |
TMEM106C,HIVEP3,PIGN,TMEM184B,THOC1,B4GALT5,POC1A,MRI1,TCF3,MAGED1,VAV2,TKT,ETS1,FOXO3,NUP205,MDM2,SHC1,TTC9C,NUP107,BCL2,KNTC1,MAST2,TTLL12,C12orf75,NAA35,CLPTM1,TRIM8,TNFAIP3,ERF,USP42,NSUN2,ILF3,CKAP2L,NUSAP1,PKMYT1,CYFIP2,PTTG1IP,MBD3,PSMB9,ASF1B,BTBD1,PRIM1,NAP1L1,MID1IP1,CDCA7L,IARS2,CHMP7,UBE2C,LONP2,EYA2,ZC3HAV1,RAD51D,TMEM131 |
| 5.524e-07 | -14.41 | GSE25085_FETAL_LIVER_VS_ADULT_BM_SP4_THYMIC_IMPLANT_UP | MSigDB lists | GSE25085_FETAL_LIVER_VS_ADULT_BM_SP4_THYMIC_IMPLANT_UP | 179 | 53 | 17377 | 2626 |
NAT9,H2AFZ,WDYHV1,MANBA,TSC22D3,UBXN1,UROD,PMS2,NANS,COMMD8,PIP4K2A,KIFC1,HNRNPA2B1,RFWD3,IMPAD1,TTC9C,ZNF260,SOCS6,KIF22,AHCY,TTC4,SMC4,GINS1,ANKRD37,FOPNL,BTG2,MTA2,RAD51AP1,ERLIN1,NARF,FRAT2,BORA,ADSS,MAGED2,CHCHD3,PFDN5,DAP3,KIF18B,UEVLD,ERGIC3,H2AFX,RPLP1,PIAS2,C4orf46,BTF3,CCDC125,REEP4,MZT2B,POT1,TOB1,TERF1,PDCD4,CWC25 |
| 5.567e-07 | -14.40 | GO_REGULATION_OF_CHROMOSOME_ORGANIZATION | MSigDB lists | GO_REGULATION_OF_CHROMOSOME_ORGANIZATION | 270 | 72 | 17377 | 2626 |
ZNF207,USP7,KDM4A,PTTG1,CSNK2A1,CCNB1,BECN1,TERF2IP,NEK6,AKAP8,NOC2L,CHTOP,DNMT1,PLK1,CCT2,ERCC1,EID1,TLK1,WBP2,CUL3,CDC6,AURKB,BRCA1,CDC23,RAB1A,TRIM28,IWS1,MAP3K4,PAF1,NSMCE2,UHRF2,OGT,XRCC3,GEN1,MAPK1,SMAD4,POT1,TRIP12,GORASP1,MECP2,CENPF,CTCF,MAD2L2,FBXO5,RB1,PTEN,ZNF335,AXIN2,BRD7,CTR9,H2AFY,TERF2,TGFB1,KAT2A,NEK7,MIER1,RTF1,KDM3A,CCT8,MAPK3,XRCC5,ATAD2,CDC27,GOLGA2,CDCA5,PML,RUVBL2,UBE2C,PARP10,TERF1,ESPL1,ANAPC4 |
| 5.570e-07 | -14.40 | GO_CYTOKINESIS | MSigDB lists | GO_CYTOKINESIS | 83 | 31 | 17377 | 2626 |
PLK1,RHOA,NEK7,RHOC,ACTR3,ANK3,JTB,KIF23,MYH9,RACGAP1,NUSAP1,AURKB,CNTROB,BCL2L1,SEPT7,ANLN,BECN1,STMN1,RAB11A,RHOB,DAPK3,AHCTF1,NEK6,SNX18,BIRC5,RALB,RAB35,CEP55,PRC1,CHMP4B,ESPL1 |
| 5.574e-07 | -14.40 | hydrolase activity | molecular function | GO:0016787 | 2568 | 479 | 17224 | 2647 |
RAB14,ADAM10,ABCC10,HEXB,TAP1,DHX8,USP39,LACTB2,ABHD14A,PARK7,KIFC1,PSMD1,RNASEK,RAB4A,ATP13A3,DNM2,CDC25B,PLCL2,RHBDD2,SENP1,USP34,ERCC1,RHOBTB3,NRAS,LACTB,KIF15,DDX20,MIER2,AMDHD2,USP22,MCM2,RFC2,RAB22A,RAB2B,ARF4,GINS4,BRMS1,RAD18,KIF18B,PTER,TPP2,MYO18A,PTPN7,ATP6V0C,PTPDC1,RNASEL,LONP2,HDAC2,DDX42,DDX58,HSPH1,RECQL,MUT,RHOC,CHTF18,GSPT2,TATDN3,DHX9,RAB23,KIF23,TOP2B,CYCS,MAN2B1,PSEN1,APH1B,PARN,MYL6B,WDR48,CFLAR,ATG4A,GNS,TMEM250,DDX56,PDXP,EXOSC7,SMC3,INPP5A,HDAC7,MCM5,ATIC,EFTUD2,PPP4R1,MSH2,ATP6V0A2,CPSF4,PIKFYVE,GNAI2,PPA1,NAGPA,DDX28,PIGT,CPQ,NOA1,DHX29,MTA2,MAN1B1,USF3,GTPBP4,SEPT8,USP10,DCTD,EXOSC9,RIT1,MPG,EIF4H,ABCF1,CCT8,PSMB3,RHOB,XRCC5,PTPRF,CAT,MTHFD2,NSF,DUSP3,TEX30,USP32,PPP3R1,VCPIP1,CNOT6,SMPD4,PLPP6,HEXA,NUDT3,RHOG,TP53RK,ABCA3,ATXN3,RAB11B,CHD1L,RAC1,OLA1,MYH9,NIT2,EFL1,GNB2,ABHD16A,NUDT19,RAB21,ATP2A2,RALB,MTMR4,UCHL5,MTA1,DUT,LPIN2,SEPT11,TAP2,RNASEH2A,AQR,ZC3H3,ILKAP,DCTN1,ATP6V1G1,SAP30,CPNE1,ENPP4,RFC3,ATP13A1,ERMP1,ATP6V0A1,PFKFB3,ABHD11,RAB1A,PSMB9,DHX57,DDX17,ANKZF1,AMZ2,PPP2CA,KIF2A,RAD51C,HSPA4,PPP2R5A,HINT1,ACYP1,DGCR8,RAB24,NT5C3B,HAGHL,PPA2,PPP5C,GEN1,PITRM1,EYA2,DYNC1LI2,TUBB,RHEBL1,USP13,POLQ,ADAM23,OTUD5,MANBA,TWNK,ABHD14B,ATP5F1B,BLM,IFT27,RAB11A,NEIL2,PLPP5,CAPN2,PPP1R3B,PSMD2,PTEN,PPP1R8,ARF5,PTPN11,DCP1A,CNOT6L,GTF2H2,IMPA2,MSH6,LYPLA2,PPP3CA,NUDT8,TNFAIP3,DDX24,KAT2A,GALC,TRIR,USP42,BMS1,OTUD3,RHOT1,DDX39A,GUF1,PDE3B,ARSK,MACF1,KIF11,SPPL2B,MYO1F,GNA12,PLD3,SGSH,KIF18A,POLE,ATP5MC3,TATDN2,PARG,CAPN7,LRPPRC,AEN,ASNA1,DUSP11,DDX5,PSAP,ESPL1,DDX52,ADA2,DDX47,GNPDA1,YTHDC2,MOGS,PTP4A3,ABCB10,SIRT2,KIF2C,SND1,USP48,ATP5PF,UBLCP1,EDC3,MBD4,RAB8A,RAP1A,PCNA,CDC42,EIF4A3,NT5DC1,DPYSL2,RAB35,IMPAD1,POP7,XRCC2,SRI,JOSD1,KIF22,EIF5,OGG1,ARID4A,TIMM50,ABCC5,PTPRK,RPP25,TDP1,LARS,SNRNP200,PTPN18,EXOSC6,SEPT9,LAP3,APH1A,MBLAC2,ARHGDIB,PBRM1,RAB5B,LSG1,USP21,DHX15,RHEB,DPYSL3,ABHD5,MAN2A2,SEPT1,CHD3,PPM1G,NAGLU,IARS2,QRSL1,ADAM9,CLU,VPS4A,OSGEPL1,NUDT11,NGLY1,PSMC1,ATP6V0E1,CAPN1,PCSK7,KLC1,ASAH1,PPP3CB,RAB6A,PM20D2,XPNPEP3,EPHX2,RHBDD1,CHKA,TIGAR,KIF13B,AHCY,TMEM8A,ZRANB1,ATP6V0D1,HDHD2,N4BP2,ABCC1,ABHD2,NTPCR,NUDT4,GBA,PSMA1,KRAS,SEPT7,STYXL1,PSMC4,GNAS,DNPH1,DTD1,CTSA,RUVBL2,ATP5F1A,MYO9A,NANP,RBBP4,TSEN15,USP7,CYLD,WDYHV1,DYNLL1,PMS2,RRAGC,SMARCA4,ATP6V1B2,DUSP22,CHD1,USP5,SEC11A,ANKLE1,ATP6V0B,PSMA6,IARS,PPME1,PIN1,KIF14,EXOSC1,PPP6C,PARL,MINPP1,AHCYL1,CTDSP2,SAP30L,GM2A,DNAL4,HTRA2,PSMA8,PPT1,RAB7A,PSMB7,MTMR6,NLN,DCLRE1C,EDEM2,MBD3,PEF1,RHBDF2,USP36,RAD54B,PON2,IDE,ATP1A1,DHX16,CANT1,XRCC3,USP11,LTA4H,USP53,CHID1,ABCA1,PPP2R2D,RAD51D,PDF,KIF3B,CTDP1,NADSYN1,CASP6,SHPRH,EYA1,TOR3A,AGO2,DCTN2,GNE,MYO9B,ARF1,GFM2,SPPL2A,WRNIP1,MAN1A1,PTPN2,GTPBP3,KIF5B,STARD9,CTSS,PELO,TANK,ABCD1,DDX31,ERI3,MYO5A,CAMK2G,GINS1,AMPD2,ADAM17,ACP2,RHOA,HELB,BTAF1,MIER1,ABCF2,ATP2C1,TUFM,RCOR1,PNPLA8,ATP5MF,HAGH,RHOT2,NEU1,HSPA1B,DDX23,MFN2,MTMR3,CTSL,RAB18,SEC23IP,ATP6V1D,PDCD6,UPF1,ATAD2,NEIL3,CTBS,USP20,SPCS3,PREPL,ATP6V1C1,TATDN1,PGAM1,HRAS |
| 5.575e-07 | -14.40 | SAKAI_TUMOR_INFILTRATING_MONOCYTES_DN | MSigDB lists | SAKAI_TUMOR_INFILTRATING_MONOCYTES_DN | 79 | 30 | 17377 | 2626 |
CCNC,PPIB,TXN,KAT2A,RBM8A,DDX20,DNAJA1,TAF6L,MACF1,FKBP3,CDC73,CCT8,PRDX1,SRSF1,EPB41,HNRNPA2B1,RAD51C,SUB1,PCNA,NEK1,CDC42,CDC27,LSM6,PRDX3,NUP107,PPP6C,TBPL1,GEMIN4,PTGES3,PRPF4B |
| 5.575e-07 | -14.40 | MORI_PRE_BI_LYMPHOCYTE_UP | MSigDB lists | MORI_PRE_BI_LYMPHOCYTE_UP | 79 | 30 | 17377 | 2626 |
MIF,TXN,HNRNPAB,EMB,ANKRD33B,CDCA3,MKI67,RRM1,RRM2,RACGAP1,SLC29A1,MCM2,STMN1,H2AFV,HMGN2,DTL,HSPBP1,MTHFD2,IDE,DBI,CDCA5,H2AFX,PRC1,KPNA2,ANP32E,RBBP4,UBE2C,CCNB2,TUBB,SMC4 |
| 5.628e-07 | -14.39 | SENGUPTA_NASOPHARYNGEAL_CARCINOMA_UP | MSigDB lists | SENGUPTA_NASOPHARYNGEAL_CARCINOMA_UP | 275 | 73 | 17377 | 2626 |
ZBED3,NUF2,ZNF267,IKBIP,FANCI,ARL6IP6,PRNP,HNRNPA2B1,PCNA,CCNA2,DPYSL2,DUT,SLC44A1,MINPP1,MCMBP,SRSF10,RFC3,RAD51AP1,PBK,E2F3,KIF15,RRM2,WDHD1,DNAJC9,NUSAP1,GORAB,SOX4,ANLN,CCNF,KIF18B,ZNF367,U2SURP,CEP55,STAT1,FKBP5,ADAM23,CENPF,DBF4,RRM1,TIA1,KIF23,RACGAP1,PM20D2,ZNRF3,NCAPG,ZNF92,TFRC,DTL,GART,KLHL5,CENPJ,ZNF260,PRC1,SMC4,SOCS5,GINS1,PHF20L1,ZNF84,PRKDC,KIF11,MTR,PATL1,FAS,MASTL,ZNF180,NAP1L1,ATAD2,TWSG1,RBMX,HMGB2,SRSF3,NDE1,WDR91 |
| 5.638e-07 | -14.39 | transcription factor binding | molecular function | GO:0008134 | 599 | 137 | 17224 | 2647 |
RORB,ADD1,TSC22D3,TRIM11,SIRT2,TAF6L,UBE2I,MAPK14,COMMD6,PARK7,CREM,USF1,NEK6,ZNHIT6,NOC2L,SRI,SMARCE1,ERCC1,BAZ2A,RBX1,GABPA,VHL,DDX20,BRCA1,BRMS1,HHEX,SMAD2,E2F4,ACTB,TFDP2,E2F2,PSMC1,HDAC2,PHB2,CENPF,DHX9,CHCHD2,MEF2A,CDK13,THRAP3,PSMD9,DDRGK1,RB1,NFATC3,MLX,HDAC7,BUD31,FAM89B,BCL2,MDFIC,IFRD1,CREG1,MTA2,LDB1,ARID1A,ELK1,KDM3A,DAPK3,PSMC4,CAND1,ETS2,SETD3,PIAS2,CEBPG,NUP62,YWHAZ,RUVBL2,YY1,RNF14,CDKN2A,TCF12,USP7,TRERF1,SUMO2,SMARCA4,RCOR3,PSMA6,MTA1,AKAP8,TP53BP2,RNF19A,ATF2,CDK12,CPNE1,RNF25,WBP2,NFATC2,MEF2D,DNAJA1,RBL1,HIPK2,MAFK,ARNTL,STAT1,TRIM32,NCOA1,FUS,PDCD11,SMAD4,SLC30A9,CTDP1,NCOR2,TRIP12,MECP2,TCF3,ARID5A,HMGN3,PAGR1,ETS1,MAD2L2,GTF2F1,WWP2,IRF4,BRD7,ARHGEF2,CREB1,FBL,STAT3,NCOA2,KAT2A,PRKDC,RCOR1,PRMT2,KEAP1,TFDP1,PITX1,E2F1,HMGB2,DDX5,TAF12,RBPJ,YWHAH,TAF6,USF2,PURA,IFI16,FAF1 |
| 5.661e-07 | -14.38 | MODULE_57 | MSigDB lists | MODULE_57 | 56 | 24 | 17377 | 2626 |
PLK1,PRKDC,PTTG1,DBF4,E2F3,CDC6,PKMYT1,ORC1,CCNB1,MCM2,MDM2,PCNA,CCNA2,MCM5,TFDP1,E2F1,CDC25B,CHEK2,ORC3,CDK2,CCNB2,ESPL1,CDKN2A,HDAC2 |
| 5.745e-07 | -14.37 | SRPRB (SRP receptor subunit beta) | protein interactions | 58477 | 134 | 45 | 17029 | 2761 |
SARNP,SCAMP3,UBE2Q1,PTP4A3,RAB6A,SPR,AP3S1,MAD2L2,LMNA,CD320,DDRGK1,RAB8A,ARF5,RRBP1,NABP2,TARDBP,PPP6R1,TMBIM1,TMED2,FDFT1,PPIF,STAU1,EMB,TMEM216,CUL3,RPL38,UBE4B,ADRB2,TOMM40,PDE3B,ARL5B,GOSR1,RHEB,EVC2,RDH11,SUGP1,RAB18,PLAA,TIMM29,STX18,MIA2,PQBP1,RBMS1,UPK3BL1,TRIM32 |
| 5.858e-07 | -14.35 | spindle microtubule | cellular component | GO:0005876 | 57 | 24 | 18223 | 2701 |
PLK1,KIF3B,PSRC1,SKA3,KLHL21,PARP4,CUL3,NUSAP1,AURKB,KIF11,RAB11A,HAUS2,NEIL2,SPAG5,KIF2A,CALM2,KIF18A,CDC16,KIF18B,CDC27,PRC1,KIFAP3,KNTC1,CSNK1D |
| 5.860e-07 | -14.35 | GO_CELL_CYCLE_G2_M_PHASE_TRANSITION | MSigDB lists | GO_CELL_CYCLE_G2_M_PHASE_TRANSITION | 134 | 43 | 17377 | 2626 |
FGFR1OP,MAPRE1,PPP1R12A,FOXM1,DYNLL1,DCTN2,TPX2,ENSA,CUL1,HAUS4,CCNB1,PRKACA,HAUS2,CALM2,RAB8A,CCP110,CENPJ,AKAP8,DNM2,FBXL7,CDC25B,CEP63,DCTN1,PLK1,PLK3,PKMYT1,BORA,OPTN,MASTL,HAUS8,TAF2,PCM1,BIRC5,RPS27A,ODF2,SSNA1,CHEK2,NDE1,CDK2,CCNB2,TERF1,TUBB,CSNK1D |
| 5.886e-07 | -14.35 | pancreas | COSMIC cancer mutations | pancreas | 16982 | 2559 | 17385 | 2587 |
HECA,ZBTB10,ABCC10,HEXB,TGOLN2,CCNL2,FBXO22,EEF2K,THAP4,RAD23B,ATP13A3,DNM2,ZNRD1,FTSJ3,USP34,CCDC57,ERCC1,NRAS,EHMT1,KIF15,HNRNPF,WDHD1,MIER2,DIDO1,MCM2,RAB22A,SMAD2,MID1IP1,RPS27A,MYO18A,OGT,MPV17,COX5A,SMAD1,ZNF75A,ANXA11,SLC25A33,ZNF720,SEC61G,GGA1,MUM1,CCZ1,TRIO,CUTA,RAB23,KCTD17,HAUS4,EIF2AK4,APH1B,PARN,CDC73,MYL6B,ATG4A,TMEM179B,ERV3-1,PDXP,SMC3,C4orf3,GEMIN4,MVP,NUP85,PPP6R1,PABPC1,NSUN4,PPA1,IFRD1,AGGF1,FOXK1,RBM42,GTPBP4,MAP7D1,MRPL16,ELK1,EIF4H,RDH11,MAGED2,KPNA1,ETS2,TYW5,WIPI2,RUFY3,PDLIM5,ACSF2,FAM72D,RHOG,EXOC3,STARD7,C5orf30,VTI1A,INO80E,SLC35B2,LCLAT1,RCOR3,CPNE3,KIAA1147,RBM23,ZNF420,AHCTF1,TBC1D22A,TBC1D14,GMEB1,NSFL1C,SEPT11,GPD1L,ZC3H3,ARL5A,PDCL3,SNX8,ERMP1,EID1,IDH3A,POLR2D,HTATIP2,MEF2D,TMEM147,GSTCD,TANC1,MAT2A,VPS26B,NSMCE2,CORO1C,CAMKMT,PPP5C,PITRM1,TUBB,COMMD10,ZNF445,SRSF6,HABP4,CCM2,FLOT1,BTN3A1,ATG2B,ABHD14B,PPP1R3B,GOLM1,ZBTB45,HUWE1,ZNF260,NAA50,ANXA5,LTN1,UBE3B,NAP1L4,ZNF710,ST8SIA2,RPL22L1,MED22,SPTAN1,STAU1,DDX24,TCTEX1D2,TACC1,MRS2,LDHA,HEBP2,LLPH,RAB3IP,TTC33,PICALM,SH3BP5,SLC19A1,ACOX1,FAM3C,AEN,PARP10,YWHAH,THAP5,GPATCH4,FAM129A,TRIM11,YTHDC2,SNX15,RBM8A,ENSA,NENF,SND1,RUFY1,TRIM65,ZER1,PRNP,KRR1,RAB8A,NUP210,NT5DC1,NOC2L,EIF5,TACC3,RYBP,VPS13B,PTPN18,MIOS,MBLAC2,SNRPB,CDC6,UTP3,PBRM1,ODC1,USP21,TRAM2,FBXO28,BCL7C,ARRDC1,ADAM9,DVL1,NUMB,ZNF564,FUBP1,C1orf74,CTU2,PARP12,ZCCHC9,CENPF,LAMTOR3,CHCHD2,NCKAP1,LYRM2,RSAD1,TNS3,SUB1,RINL,SSBP3,KIF13B,MBD2,XPA,AHCY,RBM3,GLE1,MRPL48,LRSAM1,HDHD2,NTPCR,NSDHL,AMD1,CAMSAP1,ZNF761,METTL22,ICAM2,STYXL1,APPL1,BBS12,ANKRD46,RXRB,SDHB,PCM1,GALNT2,TMEM168,NLRC5,RUVBL2,MYO9A,BTBD10,CCNB2,USP7,GLT8D1,RPLP2,SUCLG1,ARID2,TMX4,SLC2A1,ATP6V1B2,PCBP1,LYN,BCAP31,VAV1,MRPL50,TMEM69,PSMA6,ZNF473,ZNF302,BRPF3,TARDBP,BCAP29,CTDSP2,PRPF19,PPIF,KDM3B,MND1,CLCN3,BIRC3,RAB7A,ANKRD33B,PPIE,CHMP2B,VDAC1,EIF3H,TMEM201,GLOD4,IDE,DHX16,UHRF2,XRCC3,CHMP4B,PARD3,BCL2L12,MCM10,C19orf53,KLHL21,PDAP1,TMX3,CDCA8,GTF3A,ARF1,SLC12A9,TUBGCP2,DNAJB9,HOMER1,WBP1L,POLR1B,RNF5,RBM15B,PPAN,RHOA,RPRD1A,BTAF1,TOP3A,ARHGEF12,PCGF1,DDX23,RAB18,CACNB1,TRIM26,PDCD6,ATP6V1D,L3MBTL3,FAM110A,NEIL3,CTBS,BBX,IMPDH1,TAF12,NR2F2,PGAM1,HIPK3,IFI16,NUP188,TXN,H2AFZ,PNISR,PRKCSH,USP39,UBE2I,PARK7,SLC25A37,ASPHD2,ZNF428,RAB4A,TRA2B,SUCLG2,CISD2,TAF5L,SMARCE1,ZNF800,CDC5L,ZNF524,SGCE,OSBP2,NSUN2,USP22,CLNS1A,EIF3A,ZMYM3,DOT1L,IWS1,ANKRD10,WAS,KIF18B,TPP2,C1orf109,ZMAT3,FAM72C,B4GALT2,PRPF38B,RECQL,C9orf78,EWSR1,GADD45G,RRM1,ACAP1,B4GALT1,CYCS,FAM136A,SUPT7L,TMEM165,NPLOC4,CNOT3,WDR48,SPAG5,RTKN,CEP104,EXOSC7,KLHL5,LRRC8D,PPP4R1,MSH2,PIGG,OSTF1,FBXL7,MRPL40,TNRC18,SYTL3,FAM171A1,APOL1,EIF5A,GCC2,PRIM2,ELL2,RDH10,MFNG,RPS24,GORASP2,CAPZA2,ADRB2,CCT8,MTR,PHF6,PFDN5,SLCO4A1,TTC13,GOLGA2,RBMX,MED15,PIAS2,APPL2,SAMD8,NUDT3,CDKN2A,ZNF511,ATXN3,RAF1,KIAA0232,C2orf49,CD320,EPM2A,CCNA2,MTMR4,BRI3,TP53BP2,AQR,RBM12B,ILKAP,CDK12,SAP30,BRD4,DRAP1,NARF,LRRC8A,ELP4,ABHD11,PKMYT1,ASB13,SERP1,TRIM28,SUPT16H,EIF3K,CHMP4A,CBWD1,ATF6,XRCC4,PRPF4B,ADAM23,NDUFS1,DEPDC1,MECP2,SECISBP2,HMG20A,WWP2,SLC25A36,JAKMIP1,CCNK,DNAJC8,AXIN2,CITED2,JMJD4,ANKRD37,KAT2A,TMEM126B,RABIF,ADSL,PACS1,BMS1,KCNQ1,OTUD3,ARSK,MACF1,KIF11,KLF6,COMMD4,SMAP2,FADD,SH3GLB1,MYO1F,CBX3,TMEM127,INF2,PPP1R11,DUSP11,DDX5,WDR62,TAF6,ESPL1,PURA,DDB1,DEF6,FAM83G,IPO4,UBL3,NAT9,PIGM,LYRM4,GPR132,UBE2Q1,PTP4A3,BRIX1,MRPL19,ZNF696,SF3B2,PCYOX1L,CDC42,SYNM,GOT2,JAZF1,HADHB,RPF2,SLC35C2,CNNM3,CARM1,SRPK2,WDR41,LARS,ZCCHC10,CCDC138,LRBA,TMEM216,SUMF2,KMT2C,OGFR,PRPSAP1,ASF1B,RPL37,MAN2A2,EIF4ENIF1,NIP7,U2SURP,MIA2,ZNF268,VPS4A,ATP6V0E1,PPP1R2,PM20D2,XPNPEP3,RGS2,LYAR,FAM89B,POLR2I,TRAFD1,SUGP2,GBA,EIF2A,SYVN1,DAPK3,ARHGAP15,MASTL,UAP1,NFIL3,FN3KRP,YWHAZ,CTSA,TMEM14A,TOB1,TSEN15,ADNP2,TCF12,PRKAB1,MDH2,SMARCA4,ORC1,RRN3,UBXN2A,IARS,CD3EAP,KIF14,EXOSC1,CS,CLTB,DNAL4,CSTF1,POU2AF1,UBQLN4,NXT1,HPDL,PGGT1B,SELPLG,SMU1,ATXN1,GLO1,OGDH,BICD2,CADM1,EDEM2,HERPUD2,TOLLIP,FANCE,MBD3,PDHX,RPS9,ALKBH6,SURF4,DUS3L,ARNTL,ANP32E,FKBP5,TMEM101,CCDC125,ABCA1,PDCD2L,GCLM,RAE1,DCTN2,NUP54,CHIC2,PAWR,MXD4,DCUN1D4,PIP4K2A,XPR1,FERMT3,KIF5B,KLHL20,SEC24C,RRBP1,ARHGEF2,ANP32A,LDLRAD3,C12orf75,STAT3,MYO5A,NIPAL3,AMPD2,TXNL1,PHF20L1,DCAF6,FAM49B,TMEM39A,ATP2C1,RFFL,COG1,RCOR1,PRMT2,TFEB,LEMD2,SERF1B,UPF1,ELMO1,ZC3H7B,DTX4,ZMIZ1,TERF1,HRAS,CCDC93,FGFR1OP,TMED7,PIGQ,AGPAT1,CNTROB,PPP1R16B,MIS12,GSDMB,TTC9C,PDS5B,NUP153,SENP1,PGAP2,TMEM115,PLEKHM3,DCUN1D5,PLEKHF2,BRMS1,PWWP2B,TRIM47,WDR11,AXIN1,SMG9,TRIM52,LONP2,NDUFV2,PHF23,CERK,SLC4A2,EZH1,ITGB5,LMNA,MCTS1,DDX56,EIF2S2,SLC38A5,FOXN2,CARS2,PRRC2A,C16orf72,RB1CC1,ZMYND11,PGS1,MYBL2,UHRF1BP1,SRSF5,MPG,MATR3,CYB5A,NCDN,POLR2J,SETD3,TEX30,PTAR1,CNOT6,NDE1,EGLN1,ZNF207,ANKRD27,PPP1R37,ABCA3,SARNP,IVNS1ABP,RMI2,MON1B,TMEM97,NIT2,NUF2,ZNF267,TCF19,TMEM161B,KTN1,APP,PRKD3,CLUAP1,ATP2A2,UTP18,GRSF1,DUT,ZCCHC2,ANAPC7,RNF19A,FAM76B,CLN6,TMEM9,GCC1,RNF169,ADCY7,ATP6V1G1,ENPP4,RNPS1,CDCA2,FKBP3,GPR137,DDX17,CHCHD3,PEX5,CDC16,HIPK2,MBOAT1,TICAM1,PDXK,ZBTB11,ANXA6,TMBIM4,GMCL1,UBE4A,IL21R,ETS1,WRB,ZNF92,PNO1,CAPN2,ADD3,SUV39H2,TTLL12,TPCN1,TMX1,HNRNPM,LYPLA2,MFSD12,LDHB,PPP3CA,NUDT8,POLK,JTB,EMP3,MTMR12,ZP3,PDE3B,KIF18A,CCDC6,WNT5B,MAPK6,C4orf46,LY75,SLC25A19,RGL1,PSAP,WDR76,IGBP1,FAF1,SNAPIN,COX15,AGRN,THOC1,GNPDA1,GPBP1L1,PPP1R15B,CSNK2A1,EBNA1BP2,GIT2,BIRC2,ATPAF1,DLG5,ABL2,XRCC2,ZFYVE27,MCMBP,PTPRK,CDC37,SP3,METTL1,EXOSC6,HARS,GMFB,ESYT1,ANLN,RAB5B,RHEB,DPYSL3,TBC1D17,TIMM13,CDCA4,TONSL,NRM,NAGLU,ACTB,ZNF45,TMUB1,CTCF,ASAH1,DOCK11,CRLF3,ASXL2,LRRC14,NUS1,SLC27A4,AFF1,MDFIC,MAML1,CYTH1,NQO2,UTP15,EIF2AK1,EIF4G2,ZDHHC3,MOSPD3,ITPRIPL1,CDC27,SNAP23,TBPL1,PRMT7,KCTD7,NDUFA5,CYLD,UGP2,DYNLL1,COPE,HCFC1R1,ZADH2,GGPS1,RAD23A,ABRACL,PDK2,ATP6V0B,STRBP,DUS4L,MRPL34,PDCD2,SAP30L,CLPTM1,SLC39A9,RPL29,RPL35,BTG2,DNAJC9,FRAT2,MTMR6,NFATC2,KDM1B,ARL5B,USP36,CCDC127,MRPL2,ATP1A1,CLK3,MAFK,PSMD3,NDUFA11,CEP55,ZNF436,DNAJC17,NCOA1,SLC25A39,ZC3HC1,ZNF146,ATXN7L2,CDC40,SMAP1,GOLIM4,RRP15,DAP,GNE,SMC6,ARFIP2,NKRF,CHAC2,BZW2,WRNIP1,TMA7,SS18L1,CENPM,PTGES3,CAMK2G,MLEC,ZNF202,PPWD1,FAM50B,RHOT2,NEU1,TPD52L2,GOLGA7,TWSG1,PGRMC1,GLG1,FAM126A,RPS6KC1,UBE2C,PPCS,NDUFB6,TMEM41B,ZDHHC8,PLXNA1,CCNB1,SLC20A1,COMMD6,ABHD14A,POLR3K,C14orf119,ASAP2,SNUPN,CNPY4,PLCL2,TFG,SEH1L,ATG9A,PBK,MKI67,DDX20,AMDHD2,GALNT7,SLC17A5,CCNF,FOXRED1,RBM47,PTER,WDR4,DHTKD1,TRAF5,HDAC2,PWWP2A,HSPH1,LIME1,MAPRE1,CHTF18,ADO,KIF23,SLC35B1,NOTCH2,PMF1,JMY,NDUFAF6,FKBP1A,SLC31A1,SNX18,ATIC,ATP6V0A2,PIKFYVE,RNF135,LPCAT1,EEF1D,TMED2,PHF10,FTL,DDX28,ZNF84,SIGMAR1,PIP4K2C,RIT1,PLEC,KDM3A,SF3A2,FAS,EPRS,ZNF777,TMEM54,QARS,PPP3R1,TCOF1,NRBP1,CABLES1,DNMT3A,RWDD1,CKLF,TRIP10,SF3B1,RPS6KA1,SUZ12,CAST,RAC1,GPR89A,OLA1,SNN,GNB2,FLAD1,APLP2,KDM2A,TNPO2,CDKN1B,TALDO1,GPX4,ATP13A1,MAPRE2,RFC3,ERF,CUL3,SLBP,KIAA1586,H2AFV,POLG2,GAR1,PSMB9,DHX57,NSA2,HSPA4,MRPL55,JAK1,TBL3,GOLGA8A,SEL1L,H2AFX,KLHDC4,B4GALT3,PDCD11,ATMIN,POLQ,POU3F2,OTUD5,NCOR2,ANKRD13D,PKP4,SCAMP3,BABAM1,CDCA3,SLC25A12,BLM,TMCC3,GTF2F1,RPL17,CRAT,AHSA1,PRC1,UPF2,COPS7B,SLC38A10,CNOT6L,CNPY3,UBE2M,IFT46,TMEM160,TSHZ1,ZFP64,DENND4C,DENND1B,WDR18,RPL8,ILF3,LRRC1,RHOT1,MARK2,TSR2,ECH1,PRDX1,PLD3,NUCB1,FBXO21,GNA12,C1orf131,PRDX3,PFDN4,HNRNPH3,STX18,TFDP1,KHSRP,ASNA1,CPEB2,SSSCA1,VPS29,BYSL,S100PBP,MIB2,IER2,PTMS,NOP2,UBN1,DCAF15,NF1,ALKBH5,MOGS,UBE2Z,TAF6L,BECN1,MAPK14,SNAPC4,RNF103,BCAT2,MBD4,C18orf32,METTL14,IMPAD1,ZNHIT6,RCSD1,PHTF1,SRI,KIF22,ZBTB22,NFU1,OGG1,TRIM14,ELOF1,COPS8,FYTTD1,TRIM8,RRM2,SOX4,ABHD5,UBTF,CXXC4,PAF1,UEVLD,SPATA2,PQBP1,IARS2,ATXN2L,GALNT10,STARD3NL,RPS15,PIGN,AGTRAP,CIB1,XPO7,SRRT,ZNF449,CAPZA1,GLTP,BCL2,KIFAP3,N4BP2,HP1BP3,VOPP1,THNSL1,ISG15,CAND1,C22orf46,GNAS,TSC1,RBM25,CDCA5,ZFP90,NANP,RBBP4,ZBTB24,SMARCD1,MBD1,WASF2,MMACHC,TOMM20,IFI27L1,GNPNAT1,MPHOSPH8,HNRNPUL2,CHD1,MEAF6,C2orf68,CCDC50,AKAP8,PARL,RPN2,CHTOP,FAM3A,F2R,SCYL3,TMEM14C,ABI1,HTRA2,MOSPD1,RLIM,FAM172A,ZNF500,PSMB7,NLN,WIPF1,BOLA1,BUD13,NDUFB1,PEF1,EIF3G,BTBD1,TAB2,CHCHD1,TULP3,WDR59,CANT1,SCARB1,GAS2,USP11,SMURF1,TSPAN5,PPP2R2D,CDS2,MAGEH1,MRPL42,EYA1,CDK2AP2,MRPS26,LETMD1,KLF13,HDDC2,RGS1,MAN1A1,FBXO5,GART,PELO,TANK,BRD7,MRPL11,SAMD4B,ZDHHC18,GTF3C6,POLR3GL,WDR81,MEN1,ZNF407,MFN2,COX8A,ZRANB2,MBD6,SRSF3,ATP6V1C1,IDH3B,TATDN1,TSC2,LACTB2,CMTM6,RBM4,ANKRD39,ZNF275,RPL23A,CDKN2C,NAPG,USF1,DNAAF2,MECR,AP1M1,UPRT,CRY2,ECD,RNF26,TIPARP,LRRC59,ANKRD9,MGAT5,RHBDD2,BAK1,ZNF559,RHOBTB3,GABPA,NUTF2,WBP1,GINS4,ARF4,KRIT1,BOLA3,AHNAK,RAD18,PDRG1,RNASEL,CHPF2,OAZ1,PDCD4,SMNDC1,NXT2,HIVEP3,KIAA0100,CLSPN,RHOC,DHX9,PDCD7,PSMD9,HAUS2,COPB2,CD59,TFAP4,RNFT1,RIMS3,MEGF8,EFTUD2,FBXO7,MRPL21,CPSF4,PHKG2,LUC7L2,SRSF11,EIF3L,MTA2,TYW1,USP10,ITM2A,SSR2,BCLAF1,MTX1,SFXN5,FNTA,PDLIM1,TXNDC16,TMEM159,MRPL3,ALS2,FAM72A,TRIM41,KARS,NQO1,POC1A,PTTG1,ANK3,TPX2,TBC1D13,DAZAP2,STMN1,GLRX3,C19orf48,CBWD5,REPS1,ABHD16A,FBXL6,SH3BP1,MTA1,UBA5,CLCN6,INTS12,C8orf59,RPRD1B,SZRD1,CGGBP1,CPNE1,SEC61B,POLR2L,FAM118B,GOPC,CRNKL1,E2F3,CIRBP,RPL38,PFKFB3,GORAB,RAB1A,GIGYF1,TMEM184C,PPP2CA,KIF2A,CCDC14,LSM6,RNF38,DMWD,SNRPG,CENPBD1,USP13,MZT1,ZFP91,TRMT6,IP6K2,WDR5,SLC25A43,PMVK,IFT27,RRP36,NEIL2,SRXN1,RPA2,PSMD2,CLIC4,PDCD10,ITGB8,CBWD2,COQ4,ARF5,ARHGEF1,FBXL19,GTF2H2,TTPAL,UTP20,MAGT1,GPS2,DBI,MRFAP1L1,SSNA1,CD81,TMEM131,WDR13,FANCI,PAPOLA,CREM,FANCL,TET3,GLIS2,IL6ST,INTS1,POP7,SLC44A1,MTPN,ASB6,PLK1,RPP25,CELSR2,SEPT9,RBX1,APH1A,RAD51AP1,CKAP2L,PSMG1,UBE2V1,IL12RB1,EAF2,KRTCAP2,LUC7L,LSG1,NECAP2,C1orf122,ALG3,TRIM4,AGPAT2,CHD3,ZNF367,E2F4,PRPF4,KPNA2,BEND6,CLN3,DNAJC30,FAM208A,NGLY1,POT1,MYL12B,CCDC137,RMND5A,HJURP,PHB2,FAM53C,DNAJB2,NKD2,SDC2,KLC1,CDK13,ADCK5,COX4I1,RAB6A,DNAJB1,ARID1B,C1GALT1,MLX,UBE2Q2,CCP110,ZNF746,ARL6IP1,CTR9,NIPSNAP1,ABHD2,DCAF8,ACSL3,LDB1,MAP4K3,ARMC8,RBM38,IRF5,NMT2,RPL36,HAUS8,MBIP,ORMDL2,COX7A2L,ZDHHC7,FAM122A,SIL1,DTD1,UNC13C,BCCIP,SART1,TRAF7,NDUFAF2,TOR1AIP1,ZNF416,LAGE3,TM9SF3,ZFYVE21,RRAGC,ZNF121,OIP5,NRF1,WDR44,PIN1,PPME1,EFCAB11,RPAP1,CABLES2,TOP1MT,LMAN1,AHCYL1,STRAP,SPSB3,ZNF583,SNX25,ARHGAP17,POLR2G,KIAA0040,ZNF780B,PPT1,NUP155,DCLRE1C,MRPS14,RHBDF2,SUGP1,RBL1,FASTK,UBXN2B,STK38,AP1S1,SPRYD4,SLC22A23,H3F3A,CHID1,SMAD4,RAD51D,SLC30A9,NADSYN1,UNK,CMAS,HMGN3,NCAPG,SCYL2,FZD6,HERC3,GTPBP3,CTSS,ORC3,RNLS,YTHDC1,ACP2,CSRP1,HMGN5,METTL5,ABCF2,TUFM,RANGAP1,PNPLA8,HAGH,API5,ZFR,SEC23IP,E2F1,USP20,TMEM219,RBPJ,MAX,PDCD6IP,LUZP1,GXYLT1,ADAM10,CXXC1,TSC22D3,AP3M2,CUL1,GYG1,NANS,OAT,MYEF2,ANKRD26,PA2G4,NOL11,FIZ1,ZNF200,MARCH2,SLC26A2,SRP72,KLF10,LACTB,RFC2,CBFB,RAB2B,PRIM1,MAP3K4,HHEX,RPS14,LUC7L3,MAP4,MRPL27,BTF3,PTPDC1,CCDC59,NMD3,PTOV1,COX5B,DNAJC5,SCOC,DHPS,POLR2K,ANKH,VAV2,PRKAA1,C16orf87,GSPT2,DLGAP4,TATDN3,PXMP2,PRPF39,PSEN1,ZNF79,PDXDC1,VPS25,NDUFS7,YY1AP1,C12orf10,FAM192A,RPN1,LHX8,ARPC5,ZNRF2,DAPK1,TPST1,PIK3IP1,CYC1,SOCS5,FDFT1,PIGT,WDR1,EMB,ZNF574,C1orf35,EXOSC9,ARID1A,PTTG1IP,C9orf40,FXR1,GOSR1,MAP2K2,TWISTNB,AKAP1,XRCC5,HMGN2,PI4K2A,CAT,SEC31A,DERL1,MTHFD2,HSPBP1,CEBPG,ARAP1,FAM83D,USP32,CABIN1,SMPD4,GPI,CYTIP,TP53RK,REPS2,RAB11B,UROD,SLC39A13,POMP,BCL2L1,NUDT19,DECR1,RALB,SIAH1,LPIN2,ADCY9,SOCS6,MRPS27,TTC3,RNASEH2A,CFL1,ANKLE2,CDC123,OAF,VDAC2,EDF1,ERC1,EML4,ANKZF1,ZNF282,RAD51C,DSN1,DDOST,HINT1,DGCR8,SAFB,HAGHL,LMBR1,RWDD4,FTSJ1,NCLN,BEND3,EYA2,DYNC1LI2,B4GALT5,SLC41A1,MANBA,TKT,FAM76A,CBLL1,ARGLU1,LANCL1,POFUT1,FAM8A1,HEATR5B,HLA-A,EBP,RFWD3,NDUFA2,FUT8,FJX1,BTF3L4,PTPN11,MRPL54,FEM1B,RPL19,CNN2,NDUFA3,MTX2,MSH6,PDLIM2,LONRF3,RFXANK,FBXO9,GUF1,RPL32,ZHX1,OAZ2,NDUFS5,WDR91,GPR89B,HIGD2A,ZBED3,RORB,POLA2,ZNF76,COPA,UQCR10,HMGXB3,PHRF1,ABCB10,COMMD5,MAP1LC3B,DST,SIVA1,RAB35,GPATCH1,TCEA1,DRAM2,DEAF1,TRAPPC13,SNRNP200,NCK1,LAP3,VHL,SREK1,ARHGDIB,PITPNB,HSPB11,BRWD1,PPM1G,SH3GLB2,CRCP,BAZ1B,ACBD4,CAB39,STK11,CLU,CHEK2,ZSWIM3,TSTD2,CHPT1,MRPL13,DCAF5,CAPN1,UBE2D3,NSMCE4A,PPP1R12A,ZCCHC8,GORASP1,NACA,UBXN1,C19orf25,PCSK7,EPN1,RPL15,THRAP3,TTF1,QSOX2,NUP205,PRPF18,CHKA,DTL,MED10,ZRANB1,MCPH1,SLC12A2,ATP6V0D1,CSNK1G3,CREG1,NUDT4,RPL6,VKORC1,SLTM,EVC2,KLHL15,SIAH2,SLC16A1,EHD4,SNRNP70,C11orf1,APOL2,N4BP2L2,SNX27,CHMP2A,CORO7,FEZ2,PMS2,UCK2,UCK1,CLCC1,EXT2,MXD1,USP5,HNRNPA2B1,SAP130,NVL,PPP6C,CYB5R1,ZNF770,EBAG9,RNF25,PCGF6,METTL2A,FAM72B,PON2,HNRNPR,HPS5,STAT6,MAPK1,BRD9,TMEM33,NAT14,DNAJC2,TRIP12,SHPRH,SCYL1,VPS45,MYO9B,GFM2,SPPL2A,FASTKD3,FGFR3,MZT2A,PPIG,ZDHHC13,TMEM99,H2AFY,ATG13,NDUFS8,ERI3,FBL,FRMD8,SLC35A1,MICAL3,TGFB1,B3GALT6,ELOVL5,HEMK1,TIMMDC1,HELB,PSPC1,MIER1,SCFD2,NDRG3,CDK11A,MTMR3,MEGF9,ACAT1,CENPT,PLOD3,RAB3IL1,ZSWIM6,RAB14,ADD1,MRPS15,KDM4A,XIAP,DHX8,GLUD1,ANKRD23,PABPC4,CALM2,CDK5,PSMD1,NEK6,NSRP1,RABGAP1L,SRSF4,FNIP2,KCNAB2,PCBP2,MLST8,PLK3,ZNF672,HSDL1,MRPL43,TOPORS,MCL1,SMC2,PPFIA3,ICMT,SLC50A1,STOML2,LIMK1,ZNF689,PRDX5,ATE1,MLYCD,ATP6V0C,ST3GAL2,FBXL3,TFDP2,E2F2,PFKP,AAAS,DDX42,SSRP1,MRPL9,MRPS2,STRN4,TOP2B,ZNRF3,TMED3,DDRGK1,RAVER2,GNS,INTS7,INPP5A,MCM5,PHF14,ZNF326,UBE2QL1,NAGPA,TIMM8B,ETV3,TSPYL4,TSPAN31,DHX29,TEX10,MAN1B1,RPS10,CBFA2T2,ABCF1,RHOB,LRRC14B,DTWD1,PTPRF,SCARB2,OSBPL11,CCDC86,DUSP3,SLAIN1,MDH1,HEXA,RNF139,SNX14,ZNF296,TRERF1,UBR2,CHD1L,ACTR3,WDTC1,MYH9,CREBL2,NIPA2,PRKACA,SAFB2,ANKIB1,STAM,ARL6IP6,RAB21,SP100,ZKSCAN1,DDA1,NUP107,ANKRD13C,MAVS,CEP63,TMEM136,RBM15,ATF2,DCTN1,SHOC2,PSRC1,MAP4K4,WBP2,ATP6V0A1,NUSAP1,NDUFA7,DNAJA1,TAZ,C19orf54,TAF2,SEC61A1,WDR7,RPLP1,CBLN2,RBMS1,FUS,GEN1,LRP8,COIL,LRCH1,GALK1,ZNF786,RPS2,SESTD1,TRAK1,JMJD6,SIKE1,AKT1S1,KRI1,FBXO3,ERH,GATC,NDUFB4,PPP1R8,PRDM4,GTSE1,GEMIN6,DCP1A,SGCB,S100A6,IMPA2,NUDC,PDPK1,TK1,GUK1,TNFAIP3,GALC,ZNF512,KIAA0930,MRPS10,DDX39A,RPA1,ZNF180,ZNF862,KEAP1,POLE,TATDN2,PITX1,CAPN7,LRPPRC,PML,HMGB2,USF2,ANAPC4,SRM,DDX47,MCCC1,CDC42SE2,S1PR2,CDIPT,SEC16A,SSR1,LIN9,PCNA,ZNF639,TRMU,PIK3R2,ETV6,TXLNA,PPCDC,FAM86C1,MYBL1,MRPL32,CCAR1,ABCC5,PBXIP1,BAZ2A,TLK1,MRPL12,EZR,LNX2,LRP5,BRCA1,PRKRA,STX16,EPB41,OPTN,SEPT1,SOCS4,QRSL1,PIEZO1,OSGEPL1,GLCCI1,NUDT11,NAA60,GEMIN7,SEPHS2,LZTR1,RACGAP1,PPP3CB,B4GALT4,RLF,RAPGEF6,SNRNP25,RB1,VASP,MED8,VMP1,PPIL2,MEA1,TIMELESS,AHDC1,ALDH18A1,TMEM8A,ABCC1,PREB,TRAPPC9,AACS,MEMO1,KRAS,RTF1,UBE4B,NFATC2IP,LY6E,ARPC1A,ZNF174,PSMC4,GOLGA4,PALB2,SYNCRIP,PRPS2,NIPA1,TIGD2,RNF114,FOXM1,MRPL39,XAB2,SUMO2,DUSP22,COMMD8,RPL11,CSDE1,MDM2,CORO1A,METTL9,MINPP1,POC5,DVL2,GM2A,PSMA8,COQ10B,CPOX,TIGD5,SLC26A6,CYP20A1,PRPF3,TXNL4A,RPSA,SRSF1,DNAJC10,SCAP,ZNF700,PLEKHG4B,TIMM17A,TOMM6,FAU,LTA4H,AP2S1,USP53,INTS2,CTDP1,MIF4GD,CDT1,ARID5A,SUMF1,GGA2,AP3S1,CSNK1A1,RMI1,TFRC,PTPN2,STARD9,IRF4,GSTK1,NDUFV1,SLC1A4,CWC27,SLC35B4,DDX31,ABCD1,RPAP3,CNTN5,SNX2,ZMYM5,CCDC34,CHCHD6,BSDC1,KPNA4,CDKN2AIPNL,FBXO41,BIRC5,TFE3,SNAP29,CDCA7L,PKD2,ACADM,CHMP7,SAT2,GCSH,ZNF496,TMEM109,TAP1,YTHDF3,NHLRC3,IKBIP,EIF1B,ELMOD2,KIFC1,DBNDD1,CYB5RL,PARPBP,RNASEK,CDC25B,PRADC1,DNMT1,NOL12,ORAI2,USO1,AKT2,NOL8,GNG7,AURKB,MCFD2,SLC25A5,ZFAND5,MAK16,STT3A,TMED10,PSMD8,EIF2D,ITGB1,PTPN7,UQCRH,RRS1,ARRB2,RTN3,ZNF598,SVIP,DDX58,WSB2,PPIB,MUT,GMFG,HLA-E,NDUFA4,MAN2B1,METTL3,CFLAR,NDUFS4,RNF121,MEX3C,KLF16,HDAC7,DAD1,BDH1,PCYT2,GNAI2,ANKHD1,MORC3,TERF2,KCTD20,SEPT8,DCTD,PKM,TOMM40,PATL1,ADSS,SERTAD2,SERF2,ZFP92,NSF,DCK,ERGIC3,ACLY,LPCAT4,VCPIP1,YY1,PPP6R2,MAP3K5,PPP6R3,RNF14,CDK2,ZC3HAV1,ZBTB37,URB2,EIF3D,MAGED1,KLHL18,ADPGK,SLC25A44,AP1B1,SDHA,PAIP2,PHC2,CRKL,MOAP1,TERF2IP,CYHR1,ZNF75D,SHC1,UCHL5,NAA35,TMBIM1,CCT2,CDKN2AIP,MKLN1,HMGN4,LYRM1,GALK2,CDC23,SHCBP1,AP4E1,PRDM11,VEZF1,PPP2R5A,ACYP1,STAT1,PPA2,TRIM32,RHEBL1,C1orf112,TCF3,MRI1,BRAP,AGPAT3,MYNN,SDF2L1,SPR,RAB11A,REEP5,FOXO3,MAD2L2,CCDC28A,PIP5K1C,RBM17,MAT2B,PTEN,CENPJ,TAGLN2,OSTC,CREB1,PACS2,NCOA2,SMC4,RNASEH2C,NEK7,NET1,PARP4,TBRG4,ANAPC2,RPL27A,YIF1A,SGSH,HGS,TTLL4,SLC38A7,MFAP1,CCDC69,BRWD3,ESYT2,SKA3,NPHP4,UBE2E2,HNRNPAB,PLXNC1,ST13,TMEM184B,DNAJC24,ZNF107,SLC29A1,KIF2C,AGFG1,SIRT2,FKBP2,USP48,UBQLN2,SNRPD3,CUTC,EDC3,UBLCP1,ZNF804A,RAP1A,THADA,EIF4A3,AP3S2,ATG3,DPYSL2,PPP1R12C,AKR1B1,NDUFB9,JOSD1,RP2,TTC4,TECR,ARID4A,FGFR1OP2,TIMM50,TDP1,DPM1,FOPNL,SLC16A7,WDR82,SLC25A22,STK17B,DHX15,CHAF1A,GEMIN5,COPS6,SASS6,RPS26,PSMC1,SLC12A7,TBC1D12,TM9SF4,ZNF768,UFC1,MED13L,TIA1,MEF2A,EPHX2,PITHD1,RHBDD1,NFATC3,BANF1,ZNF335,BUD31,YBX1,KNTC1,ACAD8,UBE3C,ZNF189,ALDH9A1,KDELR1,TSTA3,CIC,OXR1,PSMA1,SEPT7,NAP1L1,NSMF,ODF2,EXOC4,KIAA1328,NUP62,PITPNA,NAA20,PTDSS1,MZT2B,PDSS2,C7orf26,TMEM106C,IMMT,ASH1L,CHERP,WDYHV1,PLAGL2,CHKB,IRF3,TWF2,PAIP1,ANKRD28,ANKLE1,FARSA,SAR1A,SCAMP4,APOOL,PDIA6,ACSL5,TOR1AIP2,AZI2,GFER,RAD54B,TMEM41A,DAP3,ZNF317,GADD45B,AKNA,REEP4,CBX4,MIF,KIF3B,GOLPH3L,SH2D3A,CASP6,TOR3A,SRGN,DBF4,MFSD10,SAC3D1,CTNNBL1,YIF1B,CLDND1,TTC17,SLC25A1,GINS1,PAQR6,CSNK1G2,TELO2,ADAM17,HMGN1,NASP,ASPM,PPP1R21,PRKAR1B,SYMPK,TARS,SNRPA,MAPK3,HSPA1B,HLA-B,ATAD2,PLAA,ZNF330,OSBPL8,KBTBD7,PREPL |
| 5.889e-07 | -14.35 | XRCC5 (X-ray repair cross complementing 5) | protein interactions | 7520 | 244 | 70 | 17029 | 2761 |
MIB2,PHRF1,SUZ12,SUMO2,CHD1L,CSNK2A1,ORC1,UBE2I,RAD23A,TERF2IP,CSDE1,VAV1,USF1,PCNA,SNUPN,TARDBP,SRPK2,ERF,VHL,POLR2D,CUL3,NFATC2,BRCA1,DCLRE1C,VDAC1,MCM2,CHAF1A,PRIM1,SUPT16H,DDX17,PAF1,CDC16,HSPA4,TONSL,PTER,UHRF2,H2AFX,ROCK1,H3F3A,USP11,ARRB2,SMURF1,XRCC4,COIL,SSRP1,EWSR1,DHX9,TOP2B,TFAP4,RPA2,HUWE1,AHSA1,ZNF746,MSH2,H2AFY,ORC3,MSH6,TERF2,KAT2A,PRKDC,POLR2A,ISG15,XRCC5,RPA1,DERL1,POLE,WDR76,YY1,CDK2,TERF1 |
| 5.914e-07 | -14.34 | GSE17721_LPS_VS_GARDIQUIMOD_6H_BMDC_DN | MSigDB lists | GSE17721_LPS_VS_GARDIQUIMOD_6H_BMDC_DN | 184 | 54 | 17377 | 2626 |
SEPHS2,UBE2E2,TP53RK,SYS1,HEXB,LAMTOR3,CDC42SE2,XPO7,BRIX1,PRPF39,OAT,SLC20A1,STMN1,SDHA,METTL3,PNO1,XPR1,FBXO22,KRR1,SEC11A,VASP,INPP5A,ZNF639,RABGAP1L,BDH1,ARHGEF1,TMEM14C,PCBP2,CDC37,FTL,PBXIP1,NSDHL,EMB,MRPL12,HTATIP2,SSR2,GORASP2,PACS1,PRMT2,RHOT2,EIF4G2,MRPS14,CCT8,USP36,EIF3A,RPA1,NSF,ZNF330,LRPPRC,ACADM,SPCS3,PPP5C,VPS29,ADAM23 |
| 5.914e-07 | -14.34 | GSE15330_WT_VS_IKAROS_KO_MEGAKARYOCYTE_ERYTHROID_PROGENITOR_UP | MSigDB lists | GSE15330_WT_VS_IKAROS_KO_MEGAKARYOCYTE_ERYTHROID_PROGENITOR_UP | 184 | 54 | 17377 | 2626 |
ANKRD27,ADAM10,MDH2,MRI1,TMEM109,CUL1,CSNK2A1,GTF3A,CLCC1,CHAC2,LYRM2,SSR1,ATP6V0B,HDAC7,INTS1,MRPL54,FEM1B,CTR9,INTS12,ARHGEF2,MINPP1,FDFT1,SRSF10,AGGF1,NXT1,PIGT,PSPC1,TYW1,LNX2,ITM2A,USP10,PFKFB3,GLO1,C9orf40,EIF4H,ZDHHC3,EIF3A,PRDX1,MFN2,NUCB1,HSPA4,HINT1,UBXN2B,HIPK2,DBI,COX8A,TCOF1,GAS2,SNRPG,IDH3B,COIL,AAAS,TMEM33,FUBP1 |
| 5.914e-07 | -14.34 | GSE15330_HSC_VS_PRO_BCELL_UP | MSigDB lists | GSE15330_HSC_VS_PRO_BCELL_UP | 184 | 54 | 17377 | 2626 |
ZNF207,LZTR1,NSMCE4A,GPR89A,FAM76A,AGPAT3,SUMF1,GLUD1,PSMD9,IFT27,DDRGK1,MTMR4,RABGAP1L,RCSD1,OSTF1,GLE1,APOOL,SPTSSA,PRADC1,CLTB,SGCB,RPRD1B,FGFR1OP2,ALDH9A1,ADCY7,SRPK2,CYTH1,NTPCR,NEK7,SELPLG,SEPT8,ELP4,BOLA1,ESYT1,VDAC1,MCM2,FOXRED1,KLF6,GLOD4,MAP3K4,NUCB1,NAP1L1,CDKN2AIPNL,EIF4ENIF1,MAP4,FAM3C,FTSJ1,ACTB,SCARB1,TSEN15,GPR89B,FAF1,STARD3NL,SSRP1 |
| 5.914e-07 | -14.34 | GSE22886_NAIVE_VS_IGM_MEMORY_BCELL_DN | MSigDB lists | GSE22886_NAIVE_VS_IGM_MEMORY_BCELL_DN | 184 | 54 | 17377 | 2626 |
GGA1,TOR3A,CUTA,CYCS,TMED3,NANS,SND1,USP48,TWF2,AP3S1,PPP1R16B,CAPN2,DECR1,TNS3,MCM5,FUT8,RAB4A,MDFIC,CLDND1,MRPL40,MVP,PPA1,LDHB,PRPF19,PPIF,AMPD2,VOPP1,SEC61B,PTPN18,KLF10,PBXIP1,NQO2,HTATIP2,DNAJC9,OPTN,SDHB,HLA-B,MBIP,TRAM2,TPD52L2,AHNAK,ATP1A1,TFDP1,ITGB1,ACAT1,CAB39,KPNA2,CTSA,ZMIZ1,TMEM14A,NRBP1,PFKP,TUBB,EGLN1 |
| 5.914e-07 | -14.34 | GSE5142_HTERT_TRANSDUCED_VS_CTRL_CD8_TCELL_LATE_PASSAGE_CLONE_UP | MSigDB lists | GSE5142_HTERT_TRANSDUCED_VS_CTRL_CD8_TCELL_LATE_PASSAGE_CLONE_UP | 184 | 54 | 17377 | 2626 |
ZNF296,RRP15,MRPS15,PRKCSH,SEC61G,C1orf112,MRPL39,DNAJC24,KIF23,SMARCA4,PMF1,STMN1,PMVK,ABHD14A,RGS1,NUP205,CCNA2,ETV6,NUP107,GTSE1,NDUFS8,AHCY,MRPL21,LMAN1,NUP85,POLR2I,LAP3,PBK,MKI67,RRM2,CCDC34,DCUN1D5,GAR1,BORA,DDX39A,RAD54B,PRIM1,MASTL,DAP3,HINT1,KIF18B,DSN1,PSMD8,TFE3,ZNF367,CORO1C,CDCA5,MRPL27,COX5A,FKBP5,DMWD,E2F2,MZT2B,GCSH |
| 5.914e-07 | -14.34 | GSE15930_STIM_VS_STIM_AND_TRICHOSTATINA_72H_CD8_T_CELL_UP | MSigDB lists | GSE15930_STIM_VS_STIM_AND_TRICHOSTATINA_72H_CD8_T_CELL_UP | 184 | 54 | 17377 | 2626 |
SEPHS2,MIF4GD,SMAP1,MRPL9,GNPNAT1,IVNS1ABP,COPE,ASAH1,TTF1,WWP2,MAT2B,PTPN2,SEC11A,VMP1,ARF5,RAB4A,CDKN1B,ATG13,CNN2,TCEA1,ATF2,ZNRD1,SAP30L,NCOA2,PREB,SP3,DDX24,BAZ2A,KAT7,DNAJC9,FRAT2,EMP3,WDR82,GALK2,MEF2D,CAPZA2,DNAJA1,SEPT7,ANLN,ANKZF1,ANKRD10,CCDC6,LUC7L3,MRPL27,ACLY,TBPL1,HMGB2,ROCK1,NCOA1,TMEM159,CLN3,CHPT1,DDX52,S100PBP |
| 5.916e-07 | -14.34 | PSMA3 (proteasome subunit alpha 3) | protein interactions | 5684 | 281 | 78 | 17029 | 2761 |
USP7,KARS,CYLD,MDH2,PTTG1,CUL1,CSNK2A1,POMP,USP5,RAD23A,PRNP,HNRNPA2B1,MDM2,PSMD1,PSMA6,UCHL5,RAD23B,HADHB,TARDBP,PCBP2,SRPK2,PRPF19,PLK1,CCT2,EXOSC6,PSMA8,SNRPB,PSMB7,HNRNPF,AURKB,DNAJA1,PSMB9,PAF1,HHEX,PWWP2B,PSMD8,PSMD3,MIA2,ATP6V0C,ACTB,DVL1,SLC22A23,PSMC1,HDAC2,MUM1,ASAH1,ATP5F1B,WDR5,SRRT,WDR48,PSMD2,CLIC4,HUWE1,MCM5,EFTUD2,FBXO7,CTPS1,RBM42,PRRC2A,LDHA,PSMA1,GORASP2,KRAS,SYVN1,PKM,PATL1,CCT8,PSMB3,PSMC4,XRCC5,SERF2,PML,CCDC69,KHSRP,DDX5,SLAIN1,PGAM1,RAB3IL1 |
| 5.926e-07 | -14.34 | adrenal_gland-adrenal_gland-pheochromocytoma | COSMIC cancer mutations | adrenal_gland-adrenal_gland-pheochromocytoma | 15 | 11 | 17385 | 2587 |
GNAS,CDKN2C,MAX,NRAS,NF1,VHL,KRAS,MEN1,SDHA,HRAS,CDKN2A |
| 5.932e-07 | -14.34 | E2F1 (E2F transcription factor 1) | protein interactions | 1869 | 151 | 49 | 17029 | 2761 |
CTDP1,NCOR2,RECQL,XIAP,CUL1,CSNK1A1,BIRC2,JMY,RB1,MDM2,CCNA2,KDM2A,UCHL5,MSH2,ANAPC7,TP53BP2,MCPH1,DNMT1,SP3,BIRC3,KAT2A,VHL,MYBL2,CDC6,BRCA1,PRMT2,KLF6,TRIM28,BRMS1,SERTAD2,ATAD2,CDC27,BRD2,BIRC5,RBL1,MFAP1,E2F4,TFDP1,STAT1,UHRF2,E2F1,CHEK2,TFDP2,RBBP4,CDK2,E2F2,PURA,DDB1,CDKN2A |
| 5.932e-07 | -14.34 | PARK7 (Parkinsonism associated deglycase) | protein interactions | 11315 | 151 | 49 | 17029 | 2761 |
MIF,UNK,TXN,MDH2,BABAM1,NDUFA4,NIT2,THRAP3,BCL2L1,ARF1,OAT,HDGFL2,UBE2I,ATP5PF,PARK7,SPINDOC,PTEN,MTA1,GEMIN4,CHTOP,TALDO1,PDIA6,PABPC1,IMPA2,LDHB,VHL,MTA2,GOPC,LDHA,RNPS1,BCLAF1,MCM2,RAB1A,MBD3,CCT8,TRIM28,FADD,HSPA4,HINT1,PRDX3,PRDX5,PML,PIAS2,PRPF4,YWHAZ,MAP3K5,RBBP4,HNRNPDL,HDAC2 |
| 5.954e-07 | -14.33 | GCM_RAB10 | MSigDB lists | GCM_RAB10 | 161 | 49 | 17377 | 2626 |
RAB14,TMED7,GORASP1,ADO,STARD7,YTHDF3,NCKAP1,UBQLN2,SLC25A44,DCUN1D4,SAP130,GTPBP3,ASAP2,ZNF302,IMPAD1,BRD7,TNPO3,AHCYL1,ZNF770,LUC7L2,VPS13B,SLC39A9,PHF10,CLCN3,LARS,SNRNP200,MKLN1,ZNF512,CRNKL1,LRRC8A,PITPNB,MACF1,RAB22A,SH3GLB1,CAND1,IWS1,TMEM184C,FBXO21,EIF4ENIF1,WDR11,TAB2,SEL1L,PTAR1,SOCS4,CAB39,ZRANB2,RNF14,NMD3,CSNK1D |
| 5.973e-07 | -14.33 | MCM3 (minichromosome maintenance complex component 3) | protein interactions | 4172 | 130 | 44 | 17029 | 2761 |
LZTR1,MCM10,KMT2E,DBF4,PMS2,ENSA,CSNK2A1,PTP4A3,SDHA,FANCI,RPA2,MCM5,PPME1,ZNF746,TIMELESS,TCEA1,MCMBP,DCTN1,CDC5L,PLK1,RFC3,HNRNPF,POLR2D,CUL3,DDX20,CDC6,BRCA1,MCFD2,MCM2,ASF1B,POLR2A,GINS4,RPA1,SUPT16H,KEAP1,TONSL,HNRNPH3,MAPK6,STAT1,NUP62,FKBP5,CDK2,ARRB2,SSRP1 |
| 6.017e-07 | -14.32 | GO_MRNA_BINDING | MSigDB lists | GO_MRNA_BINDING | 143 | 45 | 17377 | 2626 |
UNK,RPS2,HNRNPAB,SF3B1,MECP2,RBM8A,SECISBP2,PCBP1,PARN,PARK7,RBM4,EDC3,PAIP2,HNRNPA2B1,EIF4A3,NSRP1,GRSF1,MBD2,SRSF4,DCP1A,TRA2B,TARDBP,LUC7L2,FYTTD1,RPL35,CIRBP,RNPS1,SLBP,FXR1,LUC7L,RBM38,SRSF1,EIF4ENIF1,RBM25,SYNCRIP,HNRNPR,RBMX,LUC7L3,RPS14,KHSRP,SRSF3,SNRNP70,MRPL13,RPS26,CPEB2 |
| 6.123e-07 | -14.31 | GO_RESPONSE_TO_ENDOPLASMIC_RETICULUM_STRESS | MSigDB lists | GO_RESPONSE_TO_ENDOPLASMIC_RETICULUM_STRESS | 222 | 62 | 17377 | 2626 |
TMUB1,ATXN3,ADD1,SEC61G,PPP1R15B,CXXC1,DNAJB2,FAM129A,UFC1,TMX4,TMX3,FLOT1,SDF2L1,EIF2AK4,UBQLN2,RHBDD1,RNF103,LMNA,NPLOC4,DNAJB9,SSR1,DDRGK1,RNF121,SHC1,ATP2A2,PIK3R2,UBA5,BCL2,TARDBP,PDIA6,ATP6V0D1,CTDSP2,TMX1,RNF5,PREB,DCTN1,BAK1,SEC61B,NCK1,ERLIN1,MAN1B1,UBE4B,SYVN1,EDEM2,SERP1,PSMC4,YIF1A,SEC31A,DERL1,ANKZF1,DNAJC10,SEC61A1,TATDN2,SEL1L,PML,ASNA1,ATF6,MAP3K5,PSMC1,RNF139,USP13,TMEM33 |
| 6.126e-07 | -14.31 | WRN (Werner syndrome RecQ like helicase) | protein interactions | 7486 | 53 | 24 | 17029 | 2761 |
POLK,PRKDC,SUMO2,KIAA0930,PTTG1,PRKAR1B,DHX9,BLM,WDR48,RAD54B,CHAF1A,RPA1,XRCC5,SUPT16H,WRNIP1,RPA2,PCNA,PML,H2AFX,CHEK2,POT1,CDKN2A,TERF2,CDC5L |
| 6.134e-07 | -14.30 | NDUFV1 (NADH:ubiquinone oxidoreductase core subunit V1) | protein interactions | 4723 | 86 | 33 | 17029 | 2761 |
NDUFV2,COA3,NDUFS1,EWSR1,NDUFB6,TIMMDC1,PHB2,TOR1AIP1,VDAC2,ILF3,RRM1,NDUFA4,NOTCH2,ADRB2,TOMM40,STMN1,SDHA,NDUFS7,NDUFS4,SDHB,ATP1A1,NDUFA2,NDUFB4,HNRNPR,NDUFA11,COX5A,NDUFS8,NDUFS5,TCOF1,ATP6V0D1,HTRA2,ANXA11,VPS29 |
| 6.134e-07 | -14.30 | SUB1 (SUB1 homolog, transcriptional regulator) | protein interactions | 10923 | 86 | 33 | 17029 | 2761 |
UNK,SART1,SARNP,ST13,SRSF6,NACA,CSNK2A1,ARGLU1,SCYL2,APP,CDK5,SUB1,PCNA,EIF2S2,HUWE1,BANF1,TERF2,CDC5L,POU2AF1,SP3,DEAF1,RCOR1,RANGAP1,MCM2,SEPT7,MATR3,ABCF1,SH3GLB1,POLR2A,SRSF1,KPNA1,SMURF1,CDK2 |
| 6.179e-07 | -14.30 | WD40_repeat_dom_sf | interpro domains | IPR036322 | 288 | 75 | 18492 | 2768 |
CORO7,COPA,TRAF7,WDR13,POC1A,WDTC1,GNB2,RIC1,NOL11,WDR44,UTP18,FBXW2,TAF5L,CORO1A,UTP4,STRAP,SEH1L,CSTF1,WDR41,PRPF19,MIOS,LRBA,SMU1,WDHD1,WDR82,EML4,GEMIN5,BRWD1,WDR11,SCAP,HPS5,TBL3,CORO1C,WDR59,WDR4,WDR7,PRPF4,DMWD,PPP2R2D,DCAF5,WSB2,CDC40,RAE1,STRN4,WDR5,COPB2,WDR48,RFWD3,DTL,TENM3,KNTC1,PREB,DCAF6,DCAF8,WDR1,WDR18,UTP15,WDR81,PPWD1,EIF2A,ARPC1A,RMC1,SEC31A,PLAA,PALB2,DCAF11,WIPI2,WDR76,WDR62,WDR91,RBBP4,WDR45B,BRWD3,ANAPC4,DDB1 |
| 6.183e-07 | -14.30 | FOXL1 (forkhead box L1) | protein interactions | 2300 | 126 | 43 | 17029 | 2761 |
NOP9,COPA,SF3B1,CHD1L,HNRNPUL2,MYO9B,UBE4A,NCAPG,NUP205,PA2G4,SMC3,IARS,STRBP,RRBP1,NUP107,NOC2L,KIF22,ORC3,SPIDR,PPP6R1,EEF1D,SMC4,IFRD1,SNX2,NSDHL,BTAF1,SUGP2,MAP7D1,RANGAP1,DCUN1D5,ESYT1,SMC2,TOMM40,DDX39A,SYMPK,UTP20,POLE,NSF,SMPD4,YY1,ECPAS,HDAC2,DDX52 |
| 6.230e-07 | -14.29 | ATP metabolic process | biological process | GO:0046034 | 188 | 55 | 17256 | 2622 |
GALK1,COX15,COX5B,NDUFA5,NDUFV2,NDUFS1,NDUFB6,UQCR10,MECP2,OLA1,NDUFA4,COX4I1,CYCS,ADPGK,ATP5F1B,ATP6V1B2,ATP5PF,SDHA,NDUFS7,NDUFS4,NDUFV1,NDUFA2,NDUFB4,MSH2,ATP6V0A2,NDUFB9,NDUFS8,CYC1,NDUFA3,TGFB1,GUK1,LDHA,ATP6V0A1,OGDH,NDUFA7,NDUFB1,PKM,ATP5MF,TAZ,HSPA1B,STOML2,ATP5MC3,PARG,COX7A2L,NDUFA11,COX8A,COX5A,DHTKD1,UQCRH,NDUFS5,ATP5F1A,GPI,NIPSNAP2,PGAM1,PFKP |
| 6.237e-07 | -14.29 | GSE1740_UNSTIM_VS_IFNA_STIMULATED_MCSF_IFNG_DERIVED_MACROPHAGE_DN | MSigDB lists | GSE1740_UNSTIM_VS_IFNA_STIMULATED_MCSF_IFNG_DERIVED_MACROPHAGE_DN | 175 | 52 | 17377 | 2626 |
MIB2,ANKRD13D,KIAA0100,MPHOSPH8,GGA1,UQCR10,TRAK1,TKT,LAGE3,ALKBH5,CERK,INO80E,CUTC,REEP5,BZW2,LMNA,ZER1,CDK5,IRF4,MCM5,DNAAF2,XPA,TTC9C,MRPL34,FAM89B,AKR1B1,CYC1,AQR,PRADC1,TTLL12,CLTB,TMEM14C,NUP85,SPTAN1,METTL1,SNRNP200,EMB,SLC26A6,JTB,TMEM147,GUF1,USP21,ECH1,UBTF,PDCD6,SERF2,CSK,VPS26B,DTX4,STK11,PREPL,CHPF2 |
| 6.296e-07 | -14.28 | GSE15930_NAIVE_VS_72H_IN_VITRO_STIM_CD8_TCELL_DN | MSigDB lists | GSE15930_NAIVE_VS_72H_IN_VITRO_STIM_CD8_TCELL_DN | 189 | 55 | 17377 | 2626 |
GALK1,TRIM41,TRAK1,TMEM97,KIF23,RACGAP1,POMP,FKBP2,HCFC1R1,PRKACA,IFT27,STMN1,LCLAT1,POLR3K,EBP,SNRNP25,DECR1,RPN1,NVL,SIVA1,PDS5B,PDCD2,PCYT2,DNMT1,HDHD2,S100A6,TACC3,FDFT1,ELOF1,PRIM2,TSPAN31,MKI67,HTATIP2,NUSAP1,BRCA1,ANLN,RFC2,TTC33,CDKN2AIPNL,AHNAK,BIRC5,CCDC6,RBL1,DCK,LUC7L3,OAZ2,NAGLU,CRCP,NDUFS5,RBPJ,YY1,RNF14,CCNB2,PGAM1,DDX52 |
| 6.296e-07 | -14.28 | GSE32164_ALTERNATIVELY_ACT_M2_VS_CMYC_INHIBITED_MACROPHAGE_DN | MSigDB lists | GSE32164_ALTERNATIVELY_ACT_M2_VS_CMYC_INHIBITED_MACROPHAGE_DN | 189 | 55 | 17377 | 2626 |
GALK1,TXN,UCK2,TKT,CDCA8,KIF23,ASAH1,RACGAP1,BRIX1,PCBP1,ABHD14A,RBM17,DTL,ERH,SLC31A1,GART,SUV39H2,AP3S2,DAD1,PRC1,OSTF1,RBM3,CLDND1,IMPA2,TACC3,SMC4,CLCN3,RFC3,ASPM,EMB,MAP4K4,METTL5,POLR2D,GMFB,EMP3,DNAJC9,NUSAP1,CDC6,ANLN,SOX4,KIF11,ASF1B,PRIM1,AMZ2,HSPB11,PDLIM1,BIRC5,SNAP23,CDCA5,DBI,MRPL27,H2AFX,SASS6,RPS26,GCSH |
| 6.296e-07 | -14.28 | GSE10325_BCELL_VS_LUPUS_BCELL_DN | MSigDB lists | GSE10325_BCELL_VS_LUPUS_BCELL_DN | 189 | 55 | 17377 | 2626 |
WSB2,CDS2,MRPL42,HLA-E,SUZ12,SRGN,TAP1,CDCA8,NDUFA4,HMGN3,CYCS,POMP,RAB6A,MYL6B,HLA-A,RGS1,CFLAR,MAN1A1,SEC11A,ERH,PSMA6,CDC42,ATG3,BUD31,TIPARP,SRP72,PPIF,KLF10,DPM1,LAP3,ELL2,EAF2,KIF11,PSMB9,MRPS14,RHOB,SH3GLB1,NEU1,ISG15,OPTN,FAS,C19orf54,DDOST,RBM47,MAGT1,CEP55,CTBS,STAT1,GLG1,COX5A,ANP32E,EHD4,ZMIZ1,PGAM1,LRP8 |
| 6.296e-07 | -14.28 | GSE17721_LPS_VS_POLYIC_2H_BMDC_DN | MSigDB lists | GSE17721_LPS_VS_POLYIC_2H_BMDC_DN | 189 | 55 | 17377 | 2626 |
ASH1L,DNMT3A,FEZ2,DNAJC5,C19orf53,NOP2,TOR3A,GNE,KLF13,FAM8A1,CMTM6,XPR1,SEC11A,PSMD2,GOT2,AKAP8,PACS2,LUC7L2,MORC3,PREB,SP3,B3GALT6,TRIM8,SIGMAR1,SNX2,FAM118B,DENND4C,WDR1,LDB1,POLR2D,TOP3A,CDC6,ESYT1,SOX4,CYFIP2,MCM2,CBFA2T2,MRPS14,DHX57,CYB5A,CDKN2AIPNL,PDCD6,CCDC6,STK38,AXIN1,AEN,USP20,MLYCD,ZFP90,DNAJC30,RPS26,POT1,NUDT3,FAF1,FUBP1 |
| 6.328e-07 | -14.27 | VASN (vasorin) | protein interactions | 114990 | 71 | 29 | 17029 | 2761 |
TGFB1,SRSF11,UGP2,TMX4,RPL15,NOTCH2,SRSF5,SEPT7,XPO7,CIP2A,SRSF1,RPL23A,CNOT9,CSDE1,THADA,SAFB,LTN1,TNPO3,TNPO2,ABCD1,TAF12,SRSF3,CNOT6L,CHPT1,STAT3,CNPY3,NUP85,CARM1,SRSF10 |
| 6.332e-07 | -14.27 | V$SP1_Q6_01 | MSigDB lists | V$SP1_Q6_01 | 227 | 63 | 17377 | 2626 |
RHOG,PIGN,UGP2,PHF23,ZNF768,SCYL1,SLC2A1,STMN1,SYNRG,KTN1,XPR1,CHKA,PTPN2,CALM2,APLP2,VASP,SUV39H2,ATP2A2,CD3EAP,RAB35,SEC24C,TIMELESS,ANP32A,GLTP,UPF2,TAGLN2,PCYT2,SMARCE1,SENP1,CAMK2G,ABCC1,CDC37,TGFB1,CLPTM1,ZNF524,ADAM17,POLR2I,KAT2A,NET1,IDH3A,DRAP1,LYRM1,LDB1,RTF1,WDR81,CADM1,ERC1,TRIM28,RAB2B,C1orf122,ADSS,TMED10,CORO1C,OAZ2,BCL7C,PITPNA,BTBD10,ACSF2,DDB1,CSNK1D,PTOV1,SMARCD1,SNAPIN |
| 6.358e-07 | -14.27 | RBBP4 (RB binding protein 4, chromatin remodeling factor) | protein interactions | 5928 | 186 | 57 | 17029 | 2761 |
COX15,CYLD,HJURP,KMT2E,SUZ12,SRSF6,SUMO2,CSNK2A1,SMARCA4,PARK7,LMNA,LIN9,RB1,RPN1,USF1,HUWE1,PPP1R8,KMT5A,MTA1,MBD2,BANF1,RPN2,CREB1,DNMT1,MTPN,ARID4A,SAP30,CDC5L,SP3,TK1,NASP,VHL,MTA2,MYBL2,TOPORS,NFATC2,BRCA1,EAF2,MBD3,APPL1,PHF6,ASF1B,ISG15,CHAF1A,PSMC4,BRMS1,NAP1L1,KPNA1,CHD3,E2F1,FUS,H3F3A,TAF6,SINHCAF,CD81,DDB1,HDAC2 |
| 6.589e-07 | -14.23 | NOL12 (nucleolar protein 12) | protein interactions | 79159 | 94 | 35 | 17029 | 2761 |
NIFK,NOP2,SF3B1,MRPS26,EBNA1BP2,BRIX1,APP,SF3B2,KRR1,KRI1,RBM34,MRPS27,DDX31,ZNF770,FTSJ3,DVL2,ZNF189,FYTTD1,STAU1,DDX24,ZNF512,GTPBP4,RIOX2,MRPS10,BUD13,MRPS14,MAK16,DHX57,NSA2,ZNF689,TERF1,ZC3HAV1,GPATCH4,ZBTB24,CCDC137 |
| 6.615e-07 | -14.23 | NR3C1 (nuclear receptor subfamily 3 group C member 1) | protein interactions | 2908 | 231 | 67 | 17029 | 2761 |
KARS,PTMS,FGFR1OP,ZNF496,DDX47,NUP188,TXN,RAF1,SMARCA4,UBE2I,PRKACA,GNB2,MDM2,ZNF420,NUP210,FNIP2,ECD,SMARCE1,ANLN,TRIM28,SRSF1,DAP3,HSPA4,IDE,HNRNPR,KPNA2,FKBP5,MBOAT1,NCOA1,COPS6,PPP5C,MAPK1,HDAC2,NCOR2,CERK,LANCL1,ETS1,ARID1B,ARPC5,RBM34,MCM5,PTGES3,ALDH18A1,CREB1,STAT3,NCOA2,PPAN,DCAF6,MTA2,PRKDC,ZNF512,RCOR1,ARID1A,RXRB,KPNA1,ETS2,CCDC6,HNRNPH3,PIAS2,PML,SLC16A1,HMGB2,NR2F2,YWHAH,HNRNPDL,RNF14,SMARCD1 |
| 6.660e-07 | -14.22 | organellar ribosome | cellular component | GO:0000313 | 85 | 31 | 18223 | 2701 |
MRPL9,MRPL42,MRPS2,MRPS15,MRPL39,MRPL43,MRPL12,MRPS26,MRPS10,MRPL16,NDUFA7,MRPS14,MRPL19,MRPL50,MRPL2,DAP3,MRPL55,CHCHD1,MRPL27,MRPL34,MRPS27,MRPL54,MRPL48,MRPL40,MRPL21,MRPL11,MRPL13,NSUN4,MRPL3,MRPL32,MRPL57 |
| 6.660e-07 | -14.22 | mitochondrial ribosome | cellular component | GO:0005761 | 85 | 31 | 18223 | 2701 |
MRPL9,MRPL42,MRPS2,MRPS15,MRPL39,MRPL43,MRPL12,MRPS26,MRPS10,MRPL16,NDUFA7,MRPS14,MRPL19,MRPL50,MRPL2,DAP3,MRPL55,CHCHD1,MRPL27,MRPL34,MRPS27,MRPL54,MRPL48,MRPL40,MRPL21,MRPL11,MRPL13,NSUN4,MRPL3,MRPL32,MRPL57 |
| 6.667e-07 | -14.22 | GSE22443_IL2_VS_IL12_TREATED_ACT_CD8_TCELL_DN | MSigDB lists | GSE22443_IL2_VS_IL12_TREATED_ACT_CD8_TCELL_DN | 194 | 56 | 17377 | 2626 |
CYTIP,DNAJC5,MECP2,TCF3,CERK,RRM1,ASAH1,RPL15,RACGAP1,CLCC1,THRAP3,EIF2AK4,XPO7,TWF2,TCF19,ITGB5,RUFY1,KCMF1,VPS25,CNOT3,KIFC1,GNS,SHC1,UCHL5,PPP1R12C,H2AFY,KIF22,AHCY,ZNRD1,NAA35,DNMT1,KCNAB2,TACC3,NTPCR,PRIM2,GALC,RAD51AP1,PPP1R21,ABCF2,MYBL2,WDR82,AURKB,PSMB9,RPSA,SMAP2,RPA1,PRIM1,WAS,HINT1,VPS26B,BCL7C,SCARB1,FAU,CDK2,TUBB,HIGD2A |
| 6.693e-07 | -14.22 | GSE31082_DN_VS_CD8_SP_THYMOCYTE_UP | MSigDB lists | GSE31082_DN_VS_CD8_SP_THYMOCYTE_UP | 180 | 53 | 17377 | 2626 |
TMEM106C,SRM,GALK1,GLT8D1,H2AFZ,CLSPN,WRB,ANKRD28,ANKRD26,TMEM69,LYAR,PSMD2,PSMD1,UBE2Q2,AHCTF1,MCM5,MSH6,SEH1L,HNRNPM,ALDH9A1,FDFT1,SRSF10,GINS1,TXNL1,TELO2,MND1,PHF10,RPRD1A,AATF,PBK,OXR1,MYBL2,RNPS1,E2F3,DDX20,EXOSC9,FAM133B,NUP155,RAB1A,ARPC1A,TSR2,SNRPA,STOML2,AMZ2,IDE,PRPS2,ACLY,PTAR1,DTX4,PREPL,EHD4,IPO4,PDF |
| 6.693e-07 | -14.22 | GSE3982_MAC_VS_NEUTROPHIL_UP | MSigDB lists | GSE3982_MAC_VS_NEUTROPHIL_UP | 180 | 53 | 17377 | 2626 |
ZNF207,MMACHC,PTMS,LUZP1,ADAM10,ABCC10,YTHDC2,PTTG1,FAM76A,RRM1,GTF3A,PRPF39,SLC20A1,STAM,PSMD1,CCNA2,ATP2A2,COQ4,MRPL34,NOC2L,AP2B1,RPN2,CENPM,ALDH18A1,AHCYL1,SOCS5,PHF10,TIMM8B,AGGF1,CSRP1,RPL8,MRPL12,ADSL,NUP155,SOX4,CBFB,FKBP3,ABCF1,STOML2,DTWD1,GNA12,FBXO21,TMEM168,DDOST,HINT1,PFDN4,ACYP1,TPP2,NEIL3,ASNA1,PRPF4,SNRNP70,HDAC2 |
| 6.693e-07 | -14.22 | GCM_RAN | MSigDB lists | GCM_RAN | 180 | 53 | 17377 | 2626 |
WSB2,KIF3B,SNX27,GORASP1,MECP2,ADO,RBM8A,SNX15,ATG2B,LANCL1,BCL2L1,ATP6V1B2,FOXO3,FAM8A1,ZNF275,ZER1,MOAP1,NAPG,PDXP,BRPF3,MTMR4,PPIG,CS,TNPO2,SS18L1,CHTOP,ZNF710,SAP30L,KDM3B,PHF10,CLCN3,EXOSC6,ZNF84,TSPYL4,ZNF512,MAP4K4,ACSL3,WBP2,CRNKL1,ZFAND5,NDRG3,CAND1,DDX17,MTMR3,FBXO21,EIF4ENIF1,GOLGA7,VPS26B,FN3KRP,RBPJ,PREPL,BRD9,AAAS |
| 6.739e-07 | -14.21 | GO_NUCLEOSIDE_MONOPHOSPHATE_METABOLIC_PROCESS | MSigDB lists | GO_NUCLEOSIDE_MONOPHOSPHATE_METABOLIC_PROCESS | 213 | 60 | 17377 | 2626 |
GALK1,COX5B,NDUFA5,COX15,NDUFV2,NDUFS1,NDUFB6,UQCR10,MECP2,UCK2,OLA1,UCK1,NDUFA4,COX4I1,CYCS,ADPGK,ATP6V1B2,NDUFS7,NDUFS4,NDUFV1,GART,NDUFA2,NDUFB4,ATIC,DUT,MSH2,UPRT,ATP6V0A2,NDUFB9,NDUFS8,CYC1,NDUFA3,TGFB1,AMPD2,TK1,GUK1,LDHA,ATP6V0A1,ADSL,PFKFB3,NDUFA7,OGDH,NDUFB1,TAZ,HSPA1B,STOML2,ADSS,DCK,PRPS2,NDUFA11,COX7A2L,COX8A,COX5A,IMPDH1,DHTKD1,UQCRH,NDUFS5,GPI,PGAM1,PFKP |
| 6.782e-07 | -14.20 | UBA52 (ubiquitin A-52 residue ribosomal protein fusion product 1) | protein interactions | 7311 | 102 | 37 | 17029 | 2761 |
USP7,UNK,RPS2,RPLP2,DNAJB2,UFC1,DAZAP2,CDC73,HNRNPA2B1,HERC3,EIF2S2,RPL17,MCM5,AHCYL1,CFL1,RPL35,NCK1,VDAC2,WBP2,VDAC1,MCM2,RPL27A,CLNS1A,RPL36,RPL37,HGS,SMAD2,RPL32,RPS27A,RPS14,MAPK6,ZRANB2,SMAD1,ARRB2,SMURF1,SMAD4,SSSCA1 |
| 6.782e-07 | -14.20 | Mad2l1 (MAD2 mitotic arrest deficient-like 1) | protein interactions | 56150 | 102 | 37 | 17029 | 2761 |
POLA2,BCCIP,PKP4,FOXM1,MRPS2,MRPL39,ZFP91,TOR1AIP1,TPX2,THRAP3,PMF1,SPAG5,NPLOC4,EBP,BRPF3,TIMM23,ANAPC7,CYFIP1,PRIM2,BCLAF1,DNAJA1,CDC23,DAPK3,PRIM1,NAP1L1,CDC16,CDC27,SEC61A1,STT3A,PSMD3,CDCA7L,SLC25A19,MRPL3,TUBB,PFKP,ANAPC4,PDF |
| 6.812e-07 | -14.20 | cellular protein complex disassembly | biological process | GO:0043624 | 134 | 43 | 17256 | 2622 |
MRPL9,MRPL42,MRPS2,MRPS15,MRPL39,GSPT2,MRPS26,KIF2C,STMN1,TWF2,GFM2,MRPL19,MRPL50,KIF14,MRPS27,MRPL34,MRPL54,MRPL40,MRPL48,MRPL21,MRPL11,MRPL32,MICAL3,CFL1,MRPL57,WDR1,MRPL43,MRPL12,MRPS10,MRPL16,MRPS14,KIF2A,MRPL2,DAP3,KIF18A,MRPL55,KIF18B,NSF,CHCHD1,MRPL27,VPS4A,MRPL13,MRPL3 |
| 6.840e-07 | -14.20 | MORF_RAB6A | MSigDB lists | MORF_RAB6A | 64 | 26 | 17377 | 2626 |
SP3,MRPL9,SNRNP200,RAC1,DCTN2,WBP2,ENSA,STARD7,RAB6A,XPO7,RAB1A,AP3S1,SDHA,SERP1,BCAP31,ARPC5,MTA1,SEC24C,HADHB,CS,MDH1,TCEA1,AHCYL1,MYL12B,TMED2,KDELR1 |
| 7.035e-07 | -14.17 | GSE37416_CTRL_VS_6H_F_TULARENSIS_LVS_NEUTROPHIL_UP | MSigDB lists | GSE37416_CTRL_VS_6H_F_TULARENSIS_LVS_NEUTROPHIL_UP | 171 | 51 | 17377 | 2626 |
FGFR1OP,PRPF38B,UBN1,KIAA0232,SDC2,ATG2B,XPO7,SLC25A44,TWF2,LCLAT1,BCAP31,ATP6V0B,NFATC3,ZNF75D,NDUFA2,TBC1D14,NSFL1C,MAVS,IMPA2,ABCC5,PDLIM2,FDFT1,DDX28,ABHD2,RFC3,TACC1,KIAA0040,NCK1,TSPYL4,KIAA0930,TOP3A,LNX2,RABIF,MTMR12,UBE4B,BICD2,NDUFB1,PDE3B,RFC2,HHEX,MBIP,SLC19A1,PRDX3,QARS,CTBS,APPL2,DHTKD1,TMEM219,CNOT6,NUDT3,RNF114 |
| 7.035e-07 | -14.17 | GO_MACROMOLECULE_METHYLATION | MSigDB lists | GO_MACROMOLECULE_METHYLATION | 171 | 51 | 17377 | 2626 |
ASH1L,DNMT3A,SUZ12,MECP2,CXXC1,TRMT6,CTCF,EZH1,RAB6A,SNRPD3,WDR5,METTL3,TET3,IRF4,SUV39H2,METTL14,PRDM4,ZNF335,CTR9,FBL,DNMT1,NSUN4,FTSJ3,ARID4A,CARM1,METTL1,HEMK1,BAZ2A,BTG2,MTA2,SNRPB,EHMT1,NSUN2,METTL2A,WDR82,RTF1,MEN1,KDM1B,PRMT2,ICMT,KDM3A,TRIM28,DOT1L,GNAS,SETD3,WDR4,CAMKMT,OGT,FTSJ1,PRMT7,BEND3 |
| 7.046e-07 | -14.17 | PICCALUGA_ANGIOIMMUNOBLASTIC_LYMPHOMA_DN | MSigDB lists | PICCALUGA_ANGIOIMMUNOBLASTIC_LYMPHOMA_DN | 126 | 41 | 17377 | 2626 |
ZBTB10,HECA,TSC22D3,PPP1R15B,TMX4,MYNN,RGS2,RAPGEF6,CHD1,MXD1,RGS1,RNF103,JMY,CREM,PRNP,MOAP1,MEX3C,TRA2B,EIF5,CNOT6L,TIPARP,IFRD1,KLF10,TNFAIP3,AMD1,WIPF1,MCL1,SRSF5,PNPLA8,ZFAND5,KLF6,KDM3A,STK17B,GADD45B,H3F3A,TOB1,CCDC59,RNF139,CBX4,ESYT2,ZBTB24 |
| 7.083e-07 | -14.16 | DNA binding | molecular function | GO:0003677 | 2489 | 465 | 17224 | 2647 |
ZBTB10,ZNF496,MAX,H2AFZ,CXXC1,MYEF2,PARK7,ZNF275,GLMP,PA2G4,USF1,THAP4,PARPBP,RAD23B,ZNF200,PDS5B,CRY2,NUP153,SMARCE1,TIPARP,DNMT1,ZNF800,PCBP2,CDC5L,ZNF524,ZNF672,ERCC1,ZNF559,KLF10,GABPA,KIF15,MKI67,DDX20,WDHD1,MIER2,TOPORS,MCM2,CBFB,RFC2,ZFAND5,PRIM1,ZMYM3,DOT1L,HHEX,SMAD2,RAD18,ZNF689,LUC7L3,PRDX5,MYO18A,TFDP2,SMAD1,E2F2,ZNF75A,HDAC2,SSRP1,DDX58,HIVEP3,RECQL,CLSPN,POLR2K,CHTF18,DHX9,TOP2B,ZNF79,ZNF518A,TFAP4,LHX8,KLF16,MCM5,MSH2,ZNF326,FOXN2,TNRC18,EEF1D,TERF2,ZNF84,ETV3,PRIM2,FOXK1,ZMYND11,MTA2,USF3,ZNF574,MYBL2,BCLAF1,ARID1A,MPG,ELK1,KDM3A,PHF6,HMGN2,XRCC5,ZNF777,POLR2J,ETS2,ZFP92,RBMX,PIAS2,CEBPG,YY1,ZNF511,ZNF207,SARNP,DNMT3A,TRERF1,IVNS1ABP,ZBTB37,SUZ12,RMI2,CREBL2,ZNF267,SAFB2,RCOR3,SDE2,APP,PHC2,TERF2IP,APLP2,AHCTF1,ZNF420,ZNF75D,SP100,KDM2A,ZKSCAN1,MTA1,GMEB1,NABP1,ZNF226,ATF2,ZC3H3,CDK12,CGGBP1,SAP30,RFC3,POLR2L,ERF,HMGN4,KAT7,DRAP1,WBP2,POLR2D,E2F3,NUSAP1,EDF1,MEF2D,POLG2,H2AFV,TRIM28,TAF2,VEZF1,ZNF282,RAD51C,CERS6,SAFB,FAAP100,H2AFX,STAT1,RBMS1,ATF6,CENPBD1,FUS,BEND3,GEN1,ZBTB11,XRCC4,ATMIN,POLQ,POU3F2,NCOR2,ZNF786,ZNF445,MECP2,TWNK,TCF3,MYNN,BLM,ETS1,HMG20A,FOXO3,ZNF92,NEIL2,GTF2F1,RPA2,ZBTB45,ERH,SUV39H2,HUWE1,PPP1R8,ZNF260,PRDM4,UPF2,CARF,ZNF710,CREB1,FBXL19,NCOA2,MSH6,TSHZ1,ZFP64,TNFAIP3,POLK,ZNF512,RFXANK,ILF3,PARP4,KLF6,POLR2A,RPA1,ZNF180,NUCB1,FBXO21,POLE,ZHX1,PITX1,TFDP1,LRPPRC,PML,KHSRP,HMGB2,WDR76,USF2,TAF6,PURA,THAP5,DDB1,RORB,ZBED3,POLA2,ZNF76,IER2,THOC1,HNRNPAB,UBN1,GPBP1L1,HMGXB3,ZNF107,KIF2C,TAF6L,AGFG1,SNAPC4,ZNF696,FANCI,CREM,MBD4,LIN9,TET3,PCNA,GLIS2,ZNF639,ETV6,PHTF1,XRCC2,KIF22,ZBTB22,TCEA1,MYBL1,MTPN,OGG1,ARID4A,CARM1,CCAR1,RYBP,SP3,TDP1,DEAF1,BAZ2A,RAD51AP1,ZBED5,BRCA1,EAF2,PBRM1,KMT2C,SOX4,UBTF,CXXC4,CHD3,E2F4,ZNF367,PQBP1,ACTB,ZNF268,ZNF45,POT1,FUBP1,ZNF564,RPS15,HJURP,ZNF768,NACA,CTCF,CHCHD2,MEF2A,CDK13,THRAP3,RLF,ASXL2,CRLF3,TTF1,SRRT,ARID1B,LYAR,SUB1,RB1,MLX,NFATC3,MED8,ZNF449,MBD2,SSBP3,BANF1,XPA,ZNF746,ZNF335,TIMELESS,BCL2,AFF1,AHDC1,YBX1,PREB,ZNF189,HP1BP3,CIC,LDB1,RPL6,RTF1,ZNF761,SLTM,IRF5,ZNF174,RXRB,PALB2,NFIL3,TBPL1,NLRC5,DTD1,ZFP90,RUVBL2,RBBP4,HNRNPDL,ZBTB24,ADNP2,TIGD2,TCF12,MBD1,ASH1L,ARID2,FOXM1,PMS2,ZNF416,SMARCA4,PLAGL2,ORC1,IRF3,PCBP1,CHD1,ZNF121,MXD1,RAD23A,HNRNPA2B1,CSDE1,RRN3,ANKLE1,NRF1,ZBTB21,ZNF473,STRBP,ZNF302,AKAP8,RPAP1,PDCD2,TARDBP,TOP1MT,CHTOP,SAP30L,ZNF770,ZNF583,KDM3B,POU2AF1,MND1,POLR2G,CGAS,ZNF780B,ZNF500,TIGD5,PCGF6,ATXN1,NFATC2,DCLRE1C,KDM1B,MBD3,RAD54B,ZNF317,RBL1,ZNF700,MAFK,STAT6,ARNTL,ZNF436,UHRF2,XRCC3,NCOA1,H3F3A,AKNA,MAPK1,SMAD4,CBX4,ZNF146,RAD51D,NAT14,DNAJC2,MCM10,MTERF1,ZNF316,SHPRH,CDT1,SCYL1,AGO2,ARID5A,KLF13,GTF3A,NKRF,HMGN3,MXD4,WRNIP1,IRF4,NABP2,H2AFY,BRD7,POLR1B,ORC3,STAT3,TELO2,GTF3C6,HEMK1,HMGN1,HMGN5,BTAF1,PSPC1,ZNF202,PRKDC,MIER1,ZMYM5,TOP3A,RCOR1,MEN1,ZNF407,ZFR,TFEB,LEMD2,TRIM26,UPF1,TFE3,NEIL3,BBX,E2F1,KMT2B,IMPDH1,RBPJ,MBD6,TAF12,CENPT,NR2F2,TERF1,IFI16 |
| 7.111e-07 | -14.16 | STMN1 (stathmin 1) | protein interactions | 3925 | 64 | 27 | 17029 | 2761 |
UBQLN4,HPDL,SESTD1,NADK2,CSNK2A1,RAB1A,PRKACA,TRIM28,MAPK3,NDUFV1,AHNAK,CDC42,PDLIM1,HUWE1,SIVA1,DUT,PPM1G,CDKN1B,CHEK2,AHCYL1,CDK2,STAT3,IMPA2,EEF1D,CAMK2G,SSSCA1,RLIM |
| 7.140e-07 | -14.15 | GSE39110_DAY3_VS_DAY6_POST_IMMUNIZATION_CD8_TCELL_DN | MSigDB lists | GSE39110_DAY3_VS_DAY6_POST_IMMUNIZATION_CD8_TCELL_DN | 185 | 54 | 17377 | 2626 |
HIVEP3,SKA3,MCM10,LUZP1,CLSPN,FOXM1,NDUFAF2,POC1A,CENPF,XIAP,TPX2,RACGAP1,PXMP2,NUF2,KIF2C,STMN1,DTL,CDKN2C,CCNA2,KIF22,AHCY,C12orf75,SAP30,PLK1,MND1,ASPM,NUDT4,RAD51AP1,PBK,MYBL2,E2F3,SLBP,NUSAP1,CDC6,ANLN,CCNF,SHCBP1,ARPC1A,KIF11,SNRPA,HHEX,TRAM2,KIF18B,BIRC5,LSM6,CEP55,CDCA5,KPNA2,EHD4,GEN1,CCNB2,UBE2C,ATMIN,FAM72A |
| 7.140e-07 | -14.15 | GSE20198_IL12_VS_IL12_IL18_TREATED_ACT_CD4_TCELL_UP | MSigDB lists | GSE20198_IL12_VS_IL12_IL18_TREATED_ACT_CD4_TCELL_UP | 185 | 54 | 17377 | 2626 |
OTUD5,GOLPH3L,GNPNAT1,EIF3D,TRMT6,DHX9,C5orf30,TIA1,ZFYVE21,CSNK2A1,PDCD7,CSNK1A1,BECN1,MAN1A1,RAP1A,CNPY4,ALDH18A1,AHCYL1,CNOT6L,CDC5L,TDP1,TIMM8B,MND1,EIF3L,CSRP1,NCK1,LAP3,MTA2,LYRM1,CPOX,PARP4,CRNKL1,FAM133B,EIF2A,OGDH,ZFAND5,DHX15,MAT2A,BRMS1,PON2,PRDX3,PARG,STK38,ARNTL,STAT1,PITPNA,MDH1,DDX5,PSAP,TAF12,TMEM159,TMEM14A,GCSH,SSRP1 |
| 7.140e-07 | -14.15 | GSE9006_HEALTHY_VS_TYPE_1_DIABETES_PBMC_AT_DX_UP | MSigDB lists | GSE9006_HEALTHY_VS_TYPE_1_DIABETES_PBMC_AT_DX_UP | 185 | 54 | 17377 | 2626 |
COPA,RWDD1,UGP2,SUCLG1,MRPS15,CAST,NACA,MCCC1,OLA1,TMEM97,RRAGC,KLC1,NENF,ASXL2,ITGB5,KCMF1,REPS1,CPNE3,CFLAR,NDUFS4,MCTS1,C12orf10,PSMD2,ASAP2,PSMA6,PARL,TAP2,AHCYL1,PABPC1,NCOA2,LAP3,JTB,PSMA1,MRPS10,HTATIP2,SOX4,SLC25A5,STYXL1,KIF11,SERP1,CLNS1A,PFDN5,SERTAD2,CHMP4A,SMAD2,PTER,GLG1,PGRMC1,COX5A,CLU,BTF3,SMAD1,ZMAT3,ATMIN |
| 7.140e-07 | -14.15 | GSE6259_FLT3L_INDUCED_33D1_POS_DC_VS_BCELL_DN | MSigDB lists | GSE6259_FLT3L_INDUCED_33D1_POS_DC_VS_BCELL_DN | 185 | 54 | 17377 | 2626 |
DNAJC5,ADD1,PPP1R12A,KRBA1,KDM4A,CCM2,AP3M2,ENSA,FLOT1,RACGAP1,EZH1,FOXO3,PHTF1,DNM2,ABCD1,AFF1,CDC25B,PIKFYVE,MAML1,NDUFA3,DNMT1,ATP6V0D1,N4BP2,FGFR1OP2,ARID4A,NCOA2,MAPKAPK3,ZNF512,RAD51AP1,PRKDC,MKI67,C1orf35,SLBP,NFATC2,NFATC2IP,PDE3B,WAS,JAK1,PDLIM1,NEIL3,CEP55,ADAM9,GPI,WDR76,RNASEL,BRWD3,AP2S1,TERF1,ABCA1,NIPA1,NUMB,RNF114,CWC25,S100PBP |
| 7.168e-07 | -14.15 | PARP1 (poly(ADP-ribose) polymerase 1) | protein interactions | 142 | 259 | 73 | 17029 | 2761 |
POLA2,IMMT,CYLD,NQO1,IVNS1ABP,CHD1L,UBE2I,RAD23A,TERF2IP,NRF1,USF1,PCNA,EXOSC1,ECD,DNMT1,SENP1,CARM1,CDC5L,RPL35,HMGN4,VHL,SREK1,RRM2,NFATC2,TOPORS,BRCA1,POLG2,TRIM28,USP36,SUPT16H,MAFK,HIPK2,PPM1G,UHRF2,H2AFX,H3F3A,CBX4,HDAC2,TUBB,SSRP1,EWSR1,LZTR1,PRKAA1,TCF3,CTCF,TOP2B,THRAP3,BLM,NCAPG,LMNA,GTF2F1,RPA2,HUWE1,ZNF746,BANF1,H2AFY,RPL19,BCL2,HMGN1,PRKDC,MYBL2,DDX39A,RPL27A,HMGN2,XRCC5,RPA1,CAND1,DERL1,E2F1,WDR76,ATP5F1A,CDK2,NIPSNAP2 |
| 7.169e-07 | -14.15 | GO_RNA_3_END_PROCESSING | MSigDB lists | GO_RNA_3_END_PROCESSING | 92 | 33 | 17377 | 2626 |
CDC40,SARNP,THOC1,SRSF6,RBM8A,APP,CDC73,PAPOLA,ZNF473,EXOSC7,EIF4A3,GRSF1,SRSF4,CHTOP,AHCYL1,ERI3,FBL,ZC3H3,PABPC1,CSTF1,SRSF11,EXOSC6,POLR2D,RNPS1,SLBP,EXOSC9,SRSF5,DDX39A,SYMPK,RPSA,SRSF1,PAF1,SRSF3 |
| 7.230e-07 | -14.14 | VERNELL_RETINOBLASTOMA_PATHWAY_UP | MSigDB lists | VERNELL_RETINOBLASTOMA_PATHWAY_UP | 68 | 27 | 17377 | 2626 |
RFC3,CLSPN,SUZ12,RAD51AP1,TMEM97,RRM1,RRM2,SLBP,BLM,TCF19,RMI1,ASF1B,FBXO5,CHAF1A,FANCL,PCNA,CDCA4,ATAD2,ZNF367,DCK,CDCA5,TFDP1,CDCA7L,HMGB2,CNOT6L,E2F2,MCMBP |
| 7.248e-07 | -14.14 | V$E2F_02 | MSigDB lists | V$E2F_02 | 223 | 62 | 17377 | 2626 |
H2AFZ,CLSPN,ZCCHC8,TRMT6,RMI2,SMC6,STMN1,ASXL2,FBXO5,HNRNPA2B1,TFAP4,PCNA,SMC3,CD3EAP,PPIG,FIZ1,MSH2,TRA2B,MRPL40,MCMBP,DNMT1,ARID4A,CDC5L,YTHDC1,SP3,ZNF524,NASP,APH1A,PRKDC,E2F3,ILF3,DNAJC9,RRM2,CDC6,NFATC2IP,PBRM1,PKMYT1,MCM2,H2AFV,APPL1,POLR2A,SRSF1,CBX3,CAND1,ATAD2,SYNCRIP,HNRNPR,RBL1,DCK,LUC7L3,ZNF367,PRPS2,MAPK6,KBTBD7,E2F1,AP1S1,NUP62,FKBP5,WDR62,SASS6,GEN1,PRPF4B |
| 7.248e-07 | -14.14 | V$E2F4DP2_01 | MSigDB lists | V$E2F4DP2_01 | 223 | 62 | 17377 | 2626 |
H2AFZ,CLSPN,ZCCHC8,TRMT6,RMI2,SMC6,STMN1,ASXL2,FBXO5,HNRNPA2B1,TFAP4,PCNA,SMC3,CD3EAP,PPIG,FIZ1,MSH2,TRA2B,MRPL40,MCMBP,DNMT1,ARID4A,CDC5L,YTHDC1,SP3,ZNF524,NASP,APH1A,PRKDC,E2F3,ILF3,DNAJC9,RRM2,CDC6,NFATC2IP,PBRM1,PKMYT1,MCM2,H2AFV,APPL1,POLR2A,SRSF1,CBX3,CAND1,ATAD2,SYNCRIP,HNRNPR,RBL1,DCK,LUC7L3,ZNF367,PRPS2,MAPK6,KBTBD7,E2F1,AP1S1,NUP62,FKBP5,WDR62,SASS6,GEN1,PRPF4B |
| 7.248e-07 | -14.14 | V$E2F1DP1_01 | MSigDB lists | V$E2F1DP1_01 | 223 | 62 | 17377 | 2626 |
H2AFZ,CLSPN,ZCCHC8,TRMT6,RMI2,SMC6,STMN1,ASXL2,FBXO5,HNRNPA2B1,TFAP4,PCNA,SMC3,CD3EAP,PPIG,FIZ1,MSH2,TRA2B,MRPL40,MCMBP,DNMT1,ARID4A,CDC5L,YTHDC1,SP3,ZNF524,NASP,APH1A,PRKDC,E2F3,ILF3,DNAJC9,RRM2,CDC6,NFATC2IP,PBRM1,PKMYT1,MCM2,H2AFV,APPL1,POLR2A,SRSF1,CBX3,CAND1,ATAD2,SYNCRIP,HNRNPR,RBL1,DCK,LUC7L3,ZNF367,PRPS2,MAPK6,KBTBD7,E2F1,AP1S1,NUP62,FKBP5,WDR62,SASS6,GEN1,PRPF4B |
| 7.248e-07 | -14.14 | V$E2F1DP2_01 | MSigDB lists | V$E2F1DP2_01 | 223 | 62 | 17377 | 2626 |
H2AFZ,CLSPN,ZCCHC8,TRMT6,RMI2,SMC6,STMN1,ASXL2,FBXO5,HNRNPA2B1,TFAP4,PCNA,SMC3,CD3EAP,PPIG,FIZ1,MSH2,TRA2B,MRPL40,MCMBP,DNMT1,ARID4A,CDC5L,YTHDC1,SP3,ZNF524,NASP,APH1A,PRKDC,E2F3,ILF3,DNAJC9,RRM2,CDC6,NFATC2IP,PBRM1,PKMYT1,MCM2,H2AFV,APPL1,POLR2A,SRSF1,CBX3,CAND1,ATAD2,SYNCRIP,HNRNPR,RBL1,DCK,LUC7L3,ZNF367,PRPS2,MAPK6,KBTBD7,E2F1,AP1S1,NUP62,FKBP5,WDR62,SASS6,GEN1,PRPF4B |
| 7.272e-07 | -14.13 | KPNA2 (karyopherin subunit alpha 2) | protein interactions | 3838 | 200 | 60 | 17029 | 2761 |
RECQL,IMMT,FEZ2,MAGEH1,EWSR1,PHB2,SF3B1,MAGED1,CDT1,RAC1,DCTN2,PMS2,CUL1,CTCF,SMARCA4,GMCL1,INO80E,CSNK1A1,ANKIB1,APP,HMG20A,GTF2F1,PRKD3,GART,CTNNBL1,HUWE1,TANK,AP2B1,CDKN1B,KIFAP3,TARDBP,NUP153,MVP,ARL5A,MORC3,TERF2,CDC5L,PRPF19,MTA2,CUL3,CDCA2,BRCA1,MCM2,CDK11A,EPB41,CAND1,KPNA4,KPNA1,HSPA4,CHD3,CLK3,STAT1,ACLY,NUP62,KPNA2,FUS,CHEK2,CDK2,TERF1,SMARCD1 |
| 7.279e-07 | -14.13 | NCSTN (nicastrin) | protein interactions | 23385 | 135 | 45 | 17029 | 2761 |
SART1,IMMT,TOMM20,EWSR1,NOP2,SCAMP3,TRMT6,SLC2A1,SLC25A12,USP39,TOP2B,THRAP3,PSEN1,APH1B,APP,EBP,ATP2A2,FTSJ3,SRSF10,SRSF11,ELL2,APH1A,WDR18,HNRNPF,SMU1,CRNKL1,SEPT7,SLC25A5,SRSF1,SUPT16H,YIF1A,MAGED2,ATP1A1,SURF4,RBM25,MAGT1,TMED10,HNRNPR,TIMM29,RPS14,SAFB,ATP5F1A,RRS1,ESYT2,SSRP1 |
| 7.299e-07 | -14.13 | GSE33292_DN3_THYMOCYTE_VS_TCELL_LYMPHOMA_FROM_TCF1_KO_UP | MSigDB lists | GSE33292_DN3_THYMOCYTE_VS_TCELL_LYMPHOMA_FROM_TCF1_KO_UP | 162 | 49 | 17377 | 2626 |
SRM,FGFR1OP,GCLM,FAM208B,ZBTB37,UFC1,NACA,RBM8A,VPS45,CLCC1,CDIPT,ABHD14A,FBXO3,NFATC3,UBE2Q2,BTF3L4,MSH2,H2AFY,PDCD2,RPN2,CDC25B,CITED2,YTHDC1,GCC2,LARS,KAT2A,DCAF8,WDR18,PNPLA8,VKORC1,AP4E1,GUF1,EIF3G,TARS,SH3BP5,GALNT2,SYNCRIP,FBXO28,RBM47,NIP7,LRPPRC,USP32,SPRYD4,COPS6,NGLY1,TOB1,SLC25A33,GPATCH4,NXT2 |
| 7.302e-07 | -14.13 | SUMOylation of DNA replication proteins | REACTOME pathways | R-HSA-4615885 | 46 | 22 | 10287 | 1696 |
NDC1,NUP188,RAE1,SUMO2,NUP54,CDCA8,TOP2B,RANGAP1,NUP155,AURKB,UBE2I,NUP205,PCNA,NUP210,BIRC5,NUP107,NUP62,NUP153,NUP85,NUP58,SEH1L,AAAS |
| 7.355e-07 | -14.12 | GO_NEGATIVE_REGULATION_OF_PROTEIN_MODIFICATION_BY_SMALL_PROTEIN_CONJUGATION_OR_REMOVAL | MSigDB lists | GO_NEGATIVE_REGULATION_OF_PROTEIN_MODIFICATION_BY_SMALL_PROTEIN_CONJUGATION_OR_REMOVAL | 135 | 43 | 17377 | 2626 |
TRIP12,DNAJB2,UBXN1,CCNB1,PSEN1,PSMD9,PARK7,MAD2L2,FBXO5,CDK5,PSMD2,PSMD1,PSMA6,ANAPC7,PDCL3,TNFAIP3,GTPBP4,PSMB7,PSMA1,ANAPC2,DNAJA1,CDC23,SOX4,PSMB9,PSMB3,ISG15,HSPA1B,PSMC4,CDC16,CDC27,RPS27A,PSMD8,PSMD3,LIMK1,OGT,PML,CDK2,ARRB2,UBE2C,PARP10,PSMC1,CDKN2A,ANAPC4 |
| 7.355e-07 | -14.12 | GO_RESPONSE_TO_IONIZING_RADIATION | MSigDB lists | GO_RESPONSE_TO_IONIZING_RADIATION | 135 | 43 | 17377 | 2626 |
DNMT3A,EYA1,MECP2,PRKAA1,BABAM1,TMEM109,RRM1,BCL2L1,IKBIP,BLM,MAPK14,RFWD3,INTS7,MTA1,XRCC2,DNM2,MSH2,BCL2,DNMT1,EEF1D,BAK1,ERCC1,NET1,RAD51AP1,PRKDC,BRCA1,DCLRE1C,ELK1,MEN1,RHOB,RAD54B,XRCC5,RAD51C,ITGB1,PML,H2AFX,AEN,XRCC3,STK11,CHEK2,XRCC4,IFI16,RAD51D |
| 7.423e-07 | -14.11 | TPX2 (TPX2, microtubule nucleation factor) | protein interactions | 22974 | 40 | 20 | 17029 | 2761 |
PPIF,SARNP,SCAMP3,TPX2,AURKB,BRCA1,NDUFA7,MAPK14,LMNA,RPA1,RPA2,SAP130,NAP1L1,KPNA1,DNAJC8,GOLGA2,SIAH2,RBPJ,ZNF598,CDC5L |
| 7.511e-07 | -14.10 | SUMOylation of DNA damage response and repair proteins | REACTOME pathways | R-HSA-3108214 | 78 | 31 | 10287 | 1696 |
NDC1,NSMCE4A,NUP188,RAE1,SUMO2,NUP54,SMC6,NUP155,BRCA1,BLM,UBE2I,NUP205,RPA1,PHC2,SMC3,NUP210,SP100,HDAC7,NSMCE2,PML,NUP107,PIAS2,NUP62,NUP153,XRCC4,NUP58,NUP85,CBX4,SEH1L,AAAS,CDKN2A |
| 7.568e-07 | -14.09 | GSE12845_PRE_GC_VS_DARKZONE_GC_TONSIL_BCELL_DN | MSigDB lists | GSE12845_PRE_GC_VS_DARKZONE_GC_TONSIL_BCELL_DN | 176 | 52 | 17377 | 2626 |
USP7,TBC1D12,PDCD6IP,C19orf53,ST13,UGP2,NF1,DAP,UQCR10,UBXN1,TRAK1,MON1B,KLC1,NENF,UBE4A,BLM,C2orf49,RCOR3,REEP5,RNF103,PDK2,COQ4,TANK,KIFAP3,FBXL7,ABCC1,VOPP1,PTPN18,TRAFD1,GUK1,EID1,RBX1,BTAF1,PSPC1,CDC6,MTMR12,MEN1,VDAC1,PEF1,POLG2,ARPC1A,COMMD4,PDHX,FAS,KIF2A,AMZ2,OSBPL11,POLR2J,GPS2,EIF2D,BAZ1B,FAU |
| 7.575e-07 | -14.09 | GSE2770_UNTREATED_VS_TGFB_AND_IL12_TREATED_ACT_CD4_TCELL_48H_DN | MSigDB lists | GSE2770_UNTREATED_VS_TGFB_AND_IL12_TREATED_ACT_CD4_TCELL_48H_DN | 190 | 55 | 17377 | 2626 |
PRKAB1,ADD1,GNPNAT1,NOP2,CKLF,RPLP2,MED13L,B4GALT1,C19orf48,MAPK14,POLR3K,BCAP31,TFRC,ATPAF1,XPR1,KIAA1147,BCAT2,GSTK1,ZBTB45,FBXL6,HUWE1,NT5DC1,ZNF260,CNN2,CNPY3,CSNK1G2,ACP2,MKLN1,FAM49B,TIMMDC1,PGGT1B,ZMYND11,OXR1,USP42,PPIE,PSMG1,PLEKHM3,DCLRE1C,TOMM40,RHOT1,CLNS1A,KRIT1,MYO1F,YIF1A,BRMS1,DNAJC10,KPNA1,ZHX1,U2SURP,ARNTL,ZFP90,FBXL3,YWHAH,CDKN2A,FUBP1 |
| 7.575e-07 | -14.09 | GSE41176_WT_VS_TAK1_KO_ANTI_IGM_STIM_BCELL_24H_DN | MSigDB lists | GSE41176_WT_VS_TAK1_KO_ANTI_IGM_STIM_BCELL_24H_DN | 190 | 55 | 17377 | 2626 |
RHOG,CYTIP,RPS2,KDM4A,HLA-E,TSC22D3,TKT,CDIPT,RGS2,MAPK14,RNF103,PCNA,AHCTF1,NDUFA2,PTEN,AP3S2,KIF13B,SOCS6,FAM89B,AHCY,MAP3K14,GNAI2,GPD1L,SLC35A1,PABPC1,CTDSP2,PCBP2,SPTAN1,CPNE1,MLEC,NASP,ATG9A,RABIF,BICD2,POLG2,ANKRD46,POLR2A,ABHD5,CAT,TRAM2,NAP1L1,ATP1A1,CCDC6,TULP3,RPS14,PRPS2,NFIL3,RPLP1,H2AFX,MEGF9,SLC16A1,WIPI2,GALNT10,LTA4H,TOB1 |
| 7.575e-07 | -14.09 | GSE21927_SPLEEN_C57BL6_VS_4T1_TUMOR_BALBC_MONOCYTES_UP | MSigDB lists | GSE21927_SPLEEN_C57BL6_VS_4T1_TUMOR_BALBC_MONOCYTES_UP | 190 | 55 | 17377 | 2626 |
GGNBP2,TOMM20,RPLP2,GGA1,NACA,CERK,LAMTOR3,MED13L,RPL15,COX4I1,MYO9B,MAPK14,SYNRG,PARK7,NPLOC4,PTEN,RPL17,RAB4A,FBL,RBM15,PABPC1,SPSB3,EEF1D,USP34,RPL29,EIF3L,RPL35,FAM172A,RPS10,RPL6,CIRBP,TUFM,FBXO9,SSR2,AURKB,UBE4B,PBRM1,FXR1,NDUFB1,NDRG3,PRPSAP1,RHOT2,DHX15,EIF3H,AMZ2,RPL37,PFDN5,GOLGA4,HINT1,STT3A,RPS27A,UQCRH,BTF3,LTA4H,MZT2B |
| 7.596e-07 | -14.09 | RPLP1 (ribosomal protein lateral stalk subunit P1) | protein interactions | 6176 | 131 | 44 | 17029 | 2761 |
UBE2D3,RPS15,RPS2,CYLD,RPLP2,CDK2AP2,RPL15,CUL1,CSNK2A1,CDIPT,MAP1LC3B,TMEM165,RPL11,RPL23A,RPA2,BRD7,RPL19,RPL29,CUL3,RPL38,RPL6,RPS10,RPS24,BRCA1,ADRB2,ATP5MF,RPL27A,RPSA,EIF3A,CAND1,RPL36,NSF,RPS27A,RPS14,RPLP1,FUS,COPS6,RRS1,ARRB2,IGBP1,RPS26,NUDT3,PDCD4,GEMIN7 |
| 7.639e-07 | -14.08 | GCM_PSME1 | MSigDB lists | GCM_PSME1 | 80 | 30 | 17377 | 2626 |
HMGN1,H2AFZ,RHOA,NASP,POLR2G,POLR2K,SUMO2,NACA,RPL6,PSMA1,SLBP,RPS24,ARHGDIB,SNRPD3,CBFB,PCBP1,PSMB3,RPL11,NAP1L1,PSMA6,RPL17,DUT,QARS,CAPZA1,TRA2B,RPL19,YWHAZ,TCEA1,CFL1,HNRNPM |
| 7.639e-07 | -14.08 | ZHOU_CELL_CYCLE_GENES_IN_IR_RESPONSE_6HR | MSigDB lists | ZHOU_CELL_CYCLE_GENES_IN_IR_RESPONSE_6HR | 80 | 30 | 17377 | 2626 |
POC1A,CDT1,MYBL2,CDCA8,DNAJC9,WDHD1,RACGAP1,NUSAP1,BRCA1,SMC2,MCM2,KIF11,FBXO5,HAUS8,KIFC1,RPA2,DTL,CCNA2,DSN1,MCM5,CDCA5,CEP55,H2AFX,E2F1,TIMELESS,KIF22,HMGB2,KNTC1,CDK2,SAP30 |
| 7.696e-07 | -14.08 | GO_VACUOLE | MSigDB lists | GO_VACUOLE | 1111 | 226 | 17377 | 2626 |
MIB2,CCDC93,RAB14,TSC2,AGRN,ABCC10,HEXB,PTP4A3,TGOLN2,GYG1,UBQLN2,MAP1LC3B,BECN1,RUFY1,PCYOX1L,KIFC1,NAPG,RAB8A,RAP1A,CDC42,RABGAP1L,RAB35,RAB4A,AP1M1,DNM2,AKR1B1,AP2B1,ZFYVE27,MARCH2,DRAM2,WDR41,MIOS,ATG9A,AKT2,LRBA,EZR,SLC17A5,RAB5B,RAB22A,RHEB,PLEKHF2,OPTN,AHNAK,TBC1D17,WDR11,RPS27A,GRIPAP1,NAGLU,ITGB1,ATP6V0C,VPS4A,CLN3,ATP6V0E1,CAPN1,ANXA11,NUMB,STARD3NL,UBE2D3,TBC1D12,DNAJC5,TMUB1,SCOC,GGA1,HLA-E,CCZ1,SDC2,RAB23,LAMTOR3,ACAP1,ASAH1,MAN2B1,PSEN1,TMEM165,VPS25,WDR48,GNS,SLC31A1,VMP1,ZNRF2,SNX18,ORAI1,ATP6V0A2,TMEM8A,PIKFYVE,ATP6V0D1,VOPP1,PIP4K2C,GBA,USP10,ADRB2,MAP2K2,APPL1,RHOB,PI4K2A,DERL1,CAT,SCARB2,OSBPL11,NSF,SNAP23,SIAH2,APPL2,CTSA,WIPI2,EHD4,CDK2,HEXA,SNX14,ZC3HAV1,NIPA1,ALS2,WASF2,SNX27,CHMP2A,CYTIP,ANKRD27,GNPNAT1,RAB11B,TRIP10,RAC1,ANK3,VTI1A,TMEM97,ZFYVE21,RRAGC,NIPA2,AP1B1,ATP6V1B2,LYN,STAM,APP,GNB2,CD320,USP5,CRKL,RAB21,ATP6V0B,SHC1,RALB,SIAH1,WDR44,MTMR4,TBC1D14,CLCN6,CDKN1B,RPN2,CORO1A,F2R,TMEM9,TMBIM1,GM2A,ATP6V1G1,SNX25,SNX8,CLCN3,UBQLN4,PPT1,RAB7A,GOPC,ATP6V0A1,CHMP2B,RAB1A,AP4E1,PON2,CHMP4A,ATP1A1,RAB24,VPS26B,TAB2,AP1S1,CHMP4B,TICAM1,SCARB1,MAPK1,AP2S1,CHID1,GOLIM4,ANKRD13D,ANXA6,MANBA,SRGN,TRAK1,VPS45,FLOT1,ARF1,GGA2,RAB11A,SCYL2,PIP4K2A,TFRC,HLA-A,SPPL2A,CAPN2,CTSS,ST8SIA2,TPCN1,MYO5A,ACP2,RHOA,TNFAIP3,SNX2,GALC,RFFL,KCNQ1,ZP3,SPPL2B,SH3GLB1,NEU1,MAPK3,HLA-B,TMEM127,NUCB1,HGS,SGSH,PDCD6,ATP6V1D,PRDX3,SNAP29,CCZ1B,CTBS,PML,PSAP,ATP6V1C1,CHMP7,RPS6KC1,VPS29 |
| 7.719e-07 | -14.07 | MMS19 (MMS19 homolog, cytosolic iron-sulfur assembly component) | protein interactions | 64210 | 187 | 57 | 17029 | 2761 |
POLA2,USP7,CTU2,ADD1,PHB2,RAF1,PMS2,PTP4A3,USP39,ARF1,CDIPT,GLRX3,QSOX2,HLA-A,FANCI,GTF2F1,DST,CCNK,RPN1,BABAM2,EIF2S2,SMC3,ELP5,GEMIN6,AP2B1,ARHGEF2,LTN1,RPN2,MRPL40,WDR41,PRIM2,AATF,TYW1,NARF,CUL3,ELP4,RANGAP1,PRPF3,WBP1,MCM2,PRPSAP1,MBD3,MAK16,ABCF1,PRIM1,EIF3K,MAGED2,HLA-B,ATP1A1,POLE,SURF4,KPNA2,XRCC3,IDH3B,EYA2,DDX52,SMARCD1 |
| 7.838e-07 | -14.06 | USP9X (ubiquitin specific peptidase 9, X-linked) | protein interactions | 8239 | 148 | 48 | 17029 | 2761 |
UNK,UFC1,MAGED1,UBXN1,UBQLN2,BIRC2,SRXN1,WWP2,SHC1,NEK6,HUWE1,SEC24C,ZNF746,EFTUD2,CRY2,GEMIN4,AHCYL1,TTLL12,TERF2,USP34,SNRNP200,DCAF6,BIRC3,VHL,SNRPB,CUL3,DDX20,MCL1,UBE4B,MCM2,PCGF1,CAND1,GEMIN5,AFDN,PEX5,SMAD2,BIRC5,CLK3,PTPDC1,MAP3K5,SMAD1,ECPAS,IGBP1,UBE2C,SMURF1,TERF1,SMAD4,SSSCA1 |
| 7.838e-07 | -14.06 | PABPC4 (poly(A) binding protein cytoplasmic 4) | protein interactions | 8761 | 148 | 48 | 17029 | 2761 |
SART1,COX15,CYLD,IVNS1ABP,SUZ12,RAE1,GSPT2,RPL15,CUL1,BRIX1,PRNP,RPA2,ZNF746,TARDBP,FBL,ZC3H3,PPA1,IMPA2,LUC7L2,TERF2,SRPK2,STAU1,PPT1,WDR1,RPL6,CUL3,RPL8,SREK1,BRCA1,MCM2,DDX39A,RPS9,SF3A2,DHX15,ECH1,RPA1,CAND1,NSA2,PDCD6,POLE,CLK3,ATXN2L,YWHAZ,DDX5,ARRB2,IGBP1,HNRNPDL,TERF1 |
| 7.926e-07 | -14.05 | GSK3B (glycogen synthase kinase 3 beta) | protein interactions | 2932 | 297 | 81 | 17029 | 2761 |
NAT9,ATXN3,TSC2,FOXM1,SF3B1,RPS6KA1,DYNLL1,XIAP,BCL2L1,BRIX1,PRKACA,GNB2,BIRC2,APP,EPM2A,CREM,CDK5,MDM2,DPYSL2,NSFL1C,RPF2,DNMT1,STRAP,ILKAP,DCTN1,DEAF1,BIRC3,AKT2,FRAT2,DDX20,MCL1,NFATC2,BICD2,TAZ,MAP3K4,HSPA4,MID1IP1,CHD3,TONSL,UBXN2B,AXIN1,MAP4,RPLP1,OGT,STK11,SMAD1,MAPK1,RPS2,EWSR1,KRBA1,PPP1R2,EYA1,DCTN2,NOTCH2,PSEN1,BZW2,KIF5B,EFTUD2,ZNF746,AXIN2,PTPN11,YBX1,GEMIN4,CREB1,LPCAT1,LUC7L2,ATP5IF1,PRKDC,MARK2,TSC1,CCDC6,ZHX1,QARS,DBI,ACLY,E2F1,FAM83D,KHSRP,RBPJ,SNRNP70,NRBP1 |
| 7.929e-07 | -14.05 | positive regulation of nitrogen compound metabolic process | biological process | GO:0051173 | 2965 | 538 | 17256 | 2622 |
MAP3K7CL,HEXB,XIAP,CCNL2,PPP1R16B,EDRF1,FBXO22,CALM2,CDK5,USF1,DNM2,FNIP2,ECD,TIPARP,SENP1,MLST8,BAK1,PLK3,ERCC1,AATF,GABPA,TOPORS,DCUN1D5,ARF4,STOML2,BRMS1,SMAD2,RPS27A,AXIN1,OGT,RNASEL,TFDP2,SMAD1,E2F2,OAZ1,HIVEP3,CLSPN,GGA1,PHF23,DHX9,EZH1,EIF2AK4,PSMD9,PARN,CDC73,DDRGK1,TFAP4,FOXN2,MYDGF,NUP85,PABPC1,NSUN4,FOXK1,RB1CC1,MAPKAPK3,MTA2,MYBL2,BCLAF1,SRSF5,ELK1,FNTA,ETS2,CSK,SETD3,RNF139,ALS2,EGLN1,RHOG,KARS,TRERF1,IVNS1ABP,TPX2,MYH9,CREBL2,DAZAP2,PRKACA,ANKIB1,APP,SP100,MTA1,GMEB1,RNF19A,MAVS,RBM15,ATF2,CLN6,RPRD1B,ADCY7,PSRC1,KAT7,MAP4K4,WBP2,POLR2D,CIRBP,E2F3,PFKFB3,CDCA2,MEF2D,RAB1A,TAZ,DDX17,TAF2,PPP2CA,HIPK2,RPLP1,TICAM1,LRP8,USP13,RPS2,ZFP91,HABP4,FLOT1,ABHD14B,WDR5,ETS1,PDCD10,PRDM4,PDPK1,PPP3CA,TNFAIP3,JTB,ZP3,PICALM,KEAP1,GPS2,PITX1,PML,HMGB2,PSAP,CD81,USF2,YWHAH,AGRN,THOC1,AAMDC,GPBP1L1,PPP1R15B,FAM129A,CSNK2A1,NENF,S1PR2,BIRC2,FANCI,CREM,PRNP,TET3,PCNA,GLIS2,IL6ST,ZNF639,ETV6,PIK3R2,MYBL1,MTPN,RYBP,PLK1,SP3,EXOSC6,RBX1,MRPL12,EZR,CDC6,UBE2V1,LRP5,BRCA1,EAF2,USP21,E2F4,SOCS4,ADAM9,DVL1,POT1,ZNF564,PHB2,NKD2,LAMTOR3,CTCF,CHCHD2,CDK13,PPP3CB,RLF,ASXL2,CRLF3,ARID1B,SUB1,RB1,MLX,TIGAR,SSBP3,ZNF746,CTR9,TIMELESS,MDFIC,RBM3,ICE2,MAML1,ACSL3,LDB1,UTP15,KRAS,MAP4K3,RTF1,NFATC2IP,IRF5,RXRB,PSMC4,NLRC5,TBPL1,RUVBL2,RNF114,USP7,TRAF7,FOXM1,SUMO2,LYN,PCBP1,DUSP22,BCAP31,RAD23A,NRF1,MDM2,PIN1,PDCD2,TARDBP,SPIDR,DVL2,PRPF19,TIMP2,BIRC3,POLR2G,RAB7A,BTG2,NFATC2,SRSF1,IDE,RBL1,SCAP,TIMM17A,PLGRKT,NCOA1,SMAD4,BCL2L12,SLC30A9,DAP,CDT1,AGO2,NKRF,HMGN3,CSNK1A1,PAGR1,TFRC,IRF4,SS18L1,PTGES3,RHOA,HMGN5,PRKDC,PDCD6,NEK1,TWSG1,TFE3,E2F1,PKD2,RBPJ,NR2F2,UBE2C,IFI16,H2AFZ,ZNF496,TXN,CXXC1,YTHDF3,UBE2I,CCNB1,PARK7,GLMP,NOL11,FIZ1,TRA2B,CDC25B,DNMT1,CDC5L,KLF10,AKT2,MRNIP,AURKB,USP22,CBFB,RFC2,DOT1L,MAP3K4,HHEX,SLF1,ARRB2,NMD3,HDAC2,SVIP,DDX58,HSPH1,CHTF18,PRKAA1,GADD45G,CYCS,NOTCH2,PSEN1,METTL3,WDR48,CFLAR,FKBP1A,DAPK1,MSH2,LPCAT1,GNAI2,SOCS5,EIF5A,EXOSC9,ADRB2,ARID1A,CYFIP2,FXR1,PTTG1IP,KDM3A,CCT8,MAP2K2,XRCC5,FAS,DERL1,HSPBP1,SERTAD2,GOLGA2,NSF,RBMX,CEBPG,PPP3R1,PIAS2,MAP3K5,YY1,CDK2,RNF14,ZC3HAV1,ATXN3,RAF1,RPS6KA1,EIF3D,RAC1,MAGED1,TERF2IP,CRKL,CCNA2,SHC1,RALB,LPIN2,ADCY9,MRPS27,CDKN1B,CDK12,ANKLE2,CCT2,BRD4,RFC3,CDC123,TAOK1,CUL3,EDF1,TRIM28,SERP1,SUPT16H,VEZF1,PPP2R5A,SAFB,STAT1,H2AFX,ATF6,BEND3,TRIM32,EYA2,CSNK1D,ATMIN,POU3F2,MECP2,TCF3,BABAM1,BLM,FOXO3,MAD2L2,GTF2F1,WWP2,CCNK,PTEN,AXIN2,PTPN11,CARF,CREB1,MAP3K14,CNOT6L,CITED2,MSH6,NCOA2,LONRF3,KAT2A,NEK7,ILF3,RFXANK,KLF6,MARK2,POLR2A,FADD,OAZ2,TFDP1,KHSRP,DDX5,DDB1,CCNC,ZBED3,RORB,IER2,ZNF76,HNRNPAB,KMT2E,NF1,SIRT2,UBQLN2,MAPK14,RAP1A,EIF4A3,METTL14,TCEA1,ARID4A,CARM1,ELOF1,COPS8,DEAF1,NCK1,VHL,SOX4,UBTF,PAF1,CAB39,STK11,ZNF268,CLU,CHEK2,PSMC1,PPP1R12A,GORASP1,CIB1,MEF2A,THRAP3,RHBDD1,APOPT1,DTL,NFATC3,MED10,YBX1,BCL2,ATP5IF1,ERLIN1,GBA,EIF2A,CAND1,NSMF,NUP62,ZFP90,SNRNP70,EHD4,TOB1,SMARCD1,TCF12,ASH1L,IFI27L1,PLAGL2,SMARCA4,IRF3,PAIP1,USP5,HNRNPA2B1,RRN3,BABAM2,NVL,KIF14,AKAP8,CHTOP,F2R,ABI1,HTRA2,CHP1,MOSPD1,POU2AF1,EDEM2,TOLLIP,PEF1,RPS9,HNRNPR,TAB2,STAT6,ARNTL,GADD45B,AKNA,MAPK1,SMURF1,MIF,NAT14,DNAJC2,EYA1,DBF4,KLF13,PAWR,DCUN1D4,FBXO5,FASTKD3,FGFR3,TANK,NABP2,BRD7,ARHGEF2,ATG13,STAT3,TGFB1,TELO2,COA3,HMGN1,ADAM17,DCAF6,PRKAR1B,MEN1,PRMT2,SYMPK,TFEB,HSPA1B,MAPK3,CNOT9,UPF1,ATAD2,OSBPL8,KMT2B,ZMIZ1,SLF2,HRAS |
| 7.986e-07 | -14.04 | MRPS35 (mitochondrial ribosomal protein S35) | protein interactions | 60488 | 83 | 32 | 17029 | 2761 |
NOL12,PPAN,COX15,MRPL42,RBM42,MRPS2,MRPS15,USP42,RPL6,MRPS26,ILF3,CUL3,LAMTOR3,HAUS2,CAND1,MRPL50,DAP3,COQ4,LRPPRC,RPLP1,MRPS27,H2AFX,TRMT10B,DUSP11,RRS1,SNRNP70,CFAP20,ATP6V1C1,HNRNPDL,CCDC59,ZC3H3,ZC3HAV1 |
| 8.039e-07 | -14.03 | RUVBL2 (RuvB like AAA ATPase 2) | protein interactions | 10856 | 269 | 75 | 17029 | 2761 |
USP7,CYLD,H2AFZ,TSC2,SUZ12,RBM8A,PMS2,CUL1,USP39,INO80E,PCBP1,SDHA,APP,MEAF6,MDM2,PCNA,SHC1,NEK6,UCHL5,AKAP8,TXLNA,DNM2,CRY2,TARDBP,ATF2,SENP1,PCBP2,CDC5L,SNRNP200,RPL38,CUL3,BRCA1,MCFD2,TRIM28,IWS1,PON2,HINT1,BRD2,PDRG1,ACTB,HDAC2,DDX42,RPS2,HJURP,CDC73,RPA2,HUWE1,EFTUD2,FBL,MCPH1,FDFT1,RPAP3,TELO2,NTPCR,SNX2,SUGP2,MATR3,APPL1,POLR2A,FAS,RPA1,CNOT9,DERL1,TSC1,UPF1,KPNA1,APPL2,ASNA1,RUVBL2,PPP6R3,PPP6R2,YY1,IPO4,CDKN2A,SSSCA1 |
| 8.064e-07 | -14.03 | NDUFA4 (NDUFA4, mitochondrial complex associated) | protein interactions | 4697 | 161 | 51 | 17029 | 2761 |
NDUFA5,COX15,NDUFV2,IMMT,NDUFS1,NDUFAF2,TIMM21,SLC25A12,CHCHD2,NDUFA4,ATP5PF,APP,PARK7,NDUFS7,NDUFS4,NDUFV1,NDUFA2,NDUFB4,NDUFB9,NDUFS8,CISD2,CYC1,MTX2,PHKG2,SLC25A1,TIMM50,NIPSNAP1,COA3,GUK1,TIMMDC1,CUL3,TBRG4,NDUFA7,ADRB2,ATP5MF,TOMM40,NDUFB1,FOXRED1,ECH1,STOML2,CHCHD3,SDHB,TIMM29,SNAP29,COX7A2L,MPV17,COX8A,COX5A,SLC16A1,NDUFS5,NIPSNAP2 |
| 8.091e-07 | -14.03 | GSE17721_LPS_VS_GARDIQUIMOD_1H_BMDC_DN | MSigDB lists | GSE17721_LPS_VS_GARDIQUIMOD_1H_BMDC_DN | 181 | 53 | 17377 | 2626 |
SF3B1,ACTR3,DBF4,STARD7,DUSP22,PARN,LCLAT1,PITHD1,FAM8A1,CPNE3,PIP5K1C,SSR1,USP5,LIN9,SEC11A,NAPG,RAP1A,SNX18,ZNF746,RCSD1,MDFIC,RNF26,SLC35A1,TMEM14C,GCC1,TERF2,CSTF1,ACSL5,PRIM2,KLF10,OXR1,RNF25,SLC26A6,CCDC34,USP10,BRCA1,SOX4,CCT8,NECAP2,UBTF,SCARB2,SYNCRIP,GOLGA7,DDOST,ITGB1,CANT1,MBOAT1,ATF6,ZNF830,CHMP7,MAPK1,NRBP1,SSRP1 |
| 8.096e-07 | -14.03 | LINDGREN_BLADDER_CANCER_WITH_LOH_IN_CHR9Q | MSigDB lists | LINDGREN_BLADDER_CANCER_WITH_LOH_IN_CHR9Q | 105 | 36 | 17377 | 2626 |
RAB14,C9orf78,NUP188,FOXM1,ANKH,CREBL2,SECISBP2,NANS,DUSP22,SEC16A,ZNF79,MIS12,MRPL50,NEK6,IARS,RAD23B,XPA,PPP6C,FBXW2,GLE1,ATP6V1G1,RPL35,SEC61B,CAMSAP1,PSMB7,LRRC8A,TOPORS,KIF2A,TSC1,EPRS,RNF38,FAM122A,PRPF4,TRIM32,TRIM52,PTPDC1 |
| 8.105e-07 | -14.03 | regulation of cell cycle arrest | biological process | GO:0071156 | 113 | 38 | 17256 | 2622 |
MIF,FOXM1,CCNB1,PRKACA,CNOT11,CRLF3,CNOT3,CDK5,CCNK,TFAP4,PCNA,MDM2,CENPJ,GTSE1,CDKN1B,CNOT6L,CARM1,TGFB1,PLK3,HMGN5,AKT2,BTG2,BRCA1,SOX4,CNOT9,RPS27A,E2F4,TFDP1,PML,UHRF2,E2F1,CNOT6,ZNF268,PKD2,CHEK2,TFDP2,CDK2,SLC25A33 |
| 8.111e-07 | -14.02 | COPI-dependent Golgi-to-ER retrograde traffic | REACTOME pathways | R-HSA-6811434 | 82 | 32 | 10287 | 1696 |
KIF3B,TMED7,COPA,COPE,KLC1,KIF23,RACGAP1,KIF2C,TMED3,ARF1,COPG2,COPB2,KIFC1,KIF5B,NAPG,ARF5,KIF13B,KIF22,KIFAP3,TMED2,KDELR1,KIF15,RAB1A,KIF11,ARF4,KIF2A,KIF18A,SURF4,KIF18B,TMED10,NSF,STX18 |
| 8.121e-07 | -14.02 | mRNA Splicing - Minor Pathway | REACTOME pathways | R-HSA-72165 | 53 | 24 | 10287 | 1696 |
SNRNP200,POLR2I,POLR2G,POLR2L,POLR2K,SF3B1,SNRPB,SRSF6,SF3B6,POLR2D,SNRPD3,PDCD7,TXNL4A,POLR2A,SRSF1,GTF2F1,DDX23,SF3B2,SNRNP25,POLR2J,EFTUD2,YBX1,SNRPG,DDX42 |
| 8.121e-07 | -14.02 | Metabolism of non-coding RNA | REACTOME pathways | R-HSA-194441 | 53 | 24 | 10287 | 1696 |
NDC1,NUP188,RAE1,SNRPB,NUP54,DDX20,NUP155,SNRPD3,NUP205,CLNS1A,GEMIN5,NUP210,SNUPN,NUP107,GEMIN6,NUP62,NUP153,GEMIN4,SNRPG,NUP85,NUP58,AAAS,SEH1L,GEMIN7 |
| 8.121e-07 | -14.02 | snRNP Assembly | REACTOME pathways | R-HSA-191859 | 53 | 24 | 10287 | 1696 |
NDC1,NUP188,RAE1,SNRPB,NUP54,DDX20,NUP155,SNRPD3,NUP205,CLNS1A,GEMIN5,NUP210,SNUPN,NUP107,GEMIN6,NUP62,NUP153,GEMIN4,SNRPG,NUP85,NUP58,AAAS,SEH1L,GEMIN7 |
| 8.289e-07 | -14.00 | PSMA6 (proteasome subunit alpha 6) | protein interactions | 5687 | 144 | 47 | 17029 | 2761 |
CYLD,DNAJB2,CAST,CUL1,POMP,UBQLN2,CCNB1,MAP1LC3B,RAD23A,HNRNPA2B1,PSMD2,PSMD1,PSMA6,CCNA2,HUWE1,UCHL5,FBXO7,CAPZA1,TARDBP,TXNL1,PLK1,PPP3CA,EXOSC6,PSMA8,RBX1,PSMB7,PSMA1,PSMG1,EXOSC9,BRCA1,CADM1,SYVN1,CCNF,PSMB9,CCT8,PSMB3,POLR2A,PSMC4,DERL1,WDR11,PSMD8,PSMD3,ISY1-RAB43,CDK2,ECPAS,PSMC1,USP53 |
| 8.308e-07 | -14.00 | GO_REGULATION_OF_CELL_CYCLE_G1_S_PHASE_TRANSITION | MSigDB lists | GO_REGULATION_OF_CELL_CYCLE_G1_S_PHASE_TRANSITION | 140 | 44 | 17377 | 2626 |
UBE2E2,PHB2,TCF3,SMARCA4,CCNB1,CDC73,CNOT3,RFWD3,RPA2,RB1,MDM2,PCNA,PTEN,CENPJ,KIF14,FBXO7,GTSE1,BRD7,CDKN1B,BCL2,ECD,CNOT6L,CTDSP2,CARM1,PLK3,ADAM17,BTG2,PRKDC,CDC6,PRMT2,SOX4,MEN1,RBM38,RPS27A,E2F4,TFDP1,PML,E2F1,FAM83D,PKD2,CNOT6,CHEK2,TFDP2,CDK2 |
| 8.363e-07 | -13.99 | GO_NUCLEAR_PERIPHERY | MSigDB lists | GO_NUCLEAR_PERIPHERY | 118 | 39 | 17377 | 2626 |
MBD1,NCOR2,DNMT3A,ATXN3,THOC1,PHB2,CXXC1,CENPF,EBNA1BP2,GMCL1,BLM,NUP205,LMNA,CLIC4,SMC3,AHCTF1,PSMA6,SP100,PPIG,AKAP8,NUP107,ZNF326,TNPO2,NUP153,OGG1,CFL1,HNRNPM,MORC3,TELO2,PSPC1,NARF,ATXN1,MEN1,MATR3,PML,RUVBL2,RNASEL,YY1,IPO4 |
| 8.363e-07 | -13.99 | GO_RNA_POLYMERASE_COMPLEX | MSigDB lists | GO_RNA_POLYMERASE_COMPLEX | 118 | 39 | 17377 | 2626 |
INTS2,POLA2,CTDP1,POLR2K,ZNF768,POLR3K,CDC73,GTF2F1,MED10,INTS7,CD3EAP,INTS1,INTS12,CTR9,TAF5L,POLR1B,GTF2H2,ZNRD1,RPRD1B,ERCC1,RPRD1A,POLR2I,POLR2L,POLR2G,KAT2A,HELB,POLR2D,POLR3GL,RTF1,EDF1,POLR2A,TWISTNB,PAF1,TAF2,POLR2J,TBPL1,CRCP,TAF12,TAF6 |
| 8.363e-07 | -13.99 | KARLSSON_TGFB1_TARGETS_UP | MSigDB lists | KARLSSON_TGFB1_TARGETS_UP | 118 | 39 | 17377 | 2626 |
SRM,CTU2,HSPH1,TOMM20,REPS2,RWDD1,ACTR3,GADD45G,CYCS,SLC20A1,LYAR,EIF2S2,TIMM23,UTP18,PELO,GEMIN6,RPF2,EIF5,PPA1,EIF5A,CCT2,COQ10B,IDH3A,NSUN2,GTPBP4,RRM2,USP10,KLF6,MAK16,CCT8,SLTM,EIF3A,SYNCRIP,NIP7,CHD3,BTBD10,ZMIZ1,LRP8,GCSH |
| 8.369e-07 | -13.99 | histone methylation | biological process | GO:0016571 | 88 | 32 | 17256 | 2622 |
ASH1L,KMT2E,SUZ12,MECP2,CXXC1,NSD3,EZH1,WDR5,RLF,TET3,KMT5C,SUV39H2,KMT5A,PRDM4,ZNF335,CTR9,FBL,ARID4A,CARM1,EHMT1,RTF1,WDR82,MEN1,PRMT2,KMT2C,KDM3A,DOT1L,SETD3,OGT,PRMT7,KMT2B,BEND3 |
| 8.403e-07 | -13.99 | regulation of G2/M transition of mitotic cell cycle | biological process | GO:0010389 | 199 | 57 | 17256 | 2622 |
FGFR1OP,GPR132,MAPRE1,CLSPN,DYNLL1,MECP2,CENPF,DCTN2,TPX2,CUL1,HAUS4,CCNB1,BLM,PRKACA,PSMD9,RAB11A,HAUS2,APP,FANCI,DTL,PSMD2,PSMA6,PSMD1,CCP110,CENPJ,KIF14,FBXL7,CEP63,DCTN1,PLK1,BRD4,RBX1,PSMA8,TAOK1,PSMB7,MRNIP,PSMA1,BRCA1,AURKB,PSMB9,PSMB3,HAUS8,PSMC4,RAD51C,PCM1,RPS27A,PSMD8,PSMD3,ODF2,SSNA1,VPS4A,NDE1,ZNF830,CDK2,PSMC1,TUBB,CSNK1D |
| 8.419e-07 | -13.99 | ZC3H3 (zinc finger CCCH-type containing 3) | protein interactions | 23144 | 119 | 41 | 17029 | 2761 |
MRPL9,MZT1,ZCCHC9,NOP2,THOC1,MRPS2,PTTG1,MRPS26,RPL15,BRIX1,APP,MRPL19,PABPC4,KRI1,RBM34,MRPL34,RPF2,DDX31,AHCYL1,MRPL21,ANKHD1,CTDSP2,FTSJ3,MRPL32,DDX24,GTPBP4,MRPS10,LLPH,RAB3IP,MRPS14,SRSF1,NSA2,DAP3,UPF1,RPL32,NIP7,RRS1,NKAPD1,MRPL13,PURA,SSSCA1 |
| 8.419e-07 | -13.99 | HNRNPDL (heterogeneous nuclear ribonucleoprotein D like) | protein interactions | 9987 | 119 | 41 | 17029 | 2761 |
UNK,COX15,CYLD,EWSR1,CUL1,CSNK2A1,PARK7,MRPL19,PAIP1,PABPC4,HNRNPA2B1,RPA2,ATIC,NAA50,CRY2,TARDBP,MRPL32,HNRNPM,CDKN2AIP,VHL,HNRNPF,CUL3,BRCA1,VDAC1,EIF4H,PICALM,MATR3,SRSF1,RPA1,CAND1,RPL36,HGS,AHNAK,MRPL55,HNRNPR,HNRNPH3,H2AFX,SRSF3,FUS,COPS6,SNRNP70 |
| 8.453e-07 | -13.98 | ATP binding | molecular function | GO:0005524 | 1466 | 291 | 17224 | 2647 |
ABCC10,TAP1,DHX8,GLUD1,UBE2I,EEF2K,KIFC1,CDK5,NEK6,ATP13A3,PDS5B,SUCLG2,MAST2,PLK3,RHOBTB3,AKT2,PBK,KIF15,MKI67,DDX20,SMC2,AURKB,MCM2,RFC2,MAP3K4,MKNK1,KIF18B,LIMK1,MYO18A,RNASEL,LONP2,PFKP,DDX42,DDX58,HSPH1,RECQL,CHTF18,TRIO,PRKAA1,DHX9,RRM1,CERK,KIF23,TOP2B,EIF2AK4,DDX56,SMC3,MCM5,CTPS1,MSH2,DAPK1,RTCB,PIKFYVE,PHKG2,UBE2QL1,CARS2,DDX28,COQ8A,MAPKAPK3,DHX29,PGS1,PIP4K2C,PKM,ABCF1,MAP2K2,CCT8,PI4K2A,XRCC5,EPRS,NSF,CSK,CSNK1G1,DCK,QARS,ACLY,MAP3K5,CDK2,NRBP1,ACSF2,KARS,ABCA3,TP53RK,RPS6KA1,RAF1,CHD1L,KIAA0232,ACTR3,OLA1,TPX2,MYH9,PRKACA,CBWD5,FLAD1,PRKD3,ATP2A2,UBA5,ADCY9,CLCN6,TAP2,AQR,CDK12,ADCY7,CCT2,ULK3,ATP13A1,TAOK1,MAP4K4,PFKFB3,GALK2,PKMYT1,DNAJA1,MAT2A,DHX57,DDX17,KIF2A,RAD51C,HSPA4,JAK1,HIPK2,CBWD1,PDXK,PPP5C,CSNK1D,DYNC1LI2,POLQ,PRPF4B,GALK1,TWNK,IP6K2,ATP5F1B,BLM,PMVK,PIP5K1C,SRXN1,CBWD2,GATC,TTLL12,MAP3K14,UBE2M,MSH6,SMC4,PDPK1,TK1,GUK1,DDX24,NEK7,BMS1,DDX39A,KIF11,MARK2,MYO1F,KIF18A,TTLL4,MAPK6,ASNA1,DDX5,DDX52,DDX47,UBE2E2,YTHDC2,MCCC1,UBE2Q1,UBE2Z,CSNK2A1,ABCB10,KIF2C,MAPK14,PAPOLA,ABL2,EIF4A3,TRMU,XRCC2,KIF22,ABCC5,SRPK2,PLK1,LARS,SNRNP200,HARS,TLK1,CDC6,STK17B,DHX15,CHD3,IARS2,BAZ1B,QRSL1,ACTB,STK11,CHEK2,VPS4A,ROCK1,PSMC1,SEPHS2,UBE2D3,CDK13,THRAP3,CHKA,UBE2Q2,KIF13B,ALDH18A1,N4BP2,CSNK1G3,ABCC1,NTPCR,AACS,ACSL3,MAP4K3,EIF2AK1,UBE4B,BBS12,DAPK3,MASTL,PSMC4,PRPS2,NLRC5,ATP5F1A,RUVBL2,MYO9A,EHD4,UCK2,PMS2,UCK1,SMARCA4,ORC1,CHKB,ATP6V1B2,TWF2,LYN,CHD1,FARSA,PDK2,IARS,NVL,KIF14,SCYL3,ACSL5,CLCN3,CGAS,RAD54B,ATP1A1,IDE,CLK3,DHX16,STK38,FASTK,XRCC3,MAPK1,ABCA1,RAD51D,KIF3B,NADSYN1,SHPRH,TOR3A,GNE,SCYL1,SMC6,MYO9B,CDK11B,CSNK1A1,SCYL2,PIP4K2A,WRNIP1,KIF5B,STARD9,FGFR3,GART,GRK2,DDX31,ABCD1,MYO5A,CAMK2G,CSNK1G2,HELB,PRKDC,BTAF1,ABCF2,ATP2C1,NADK2,PNPLA8,CDK11A,TARS,DDX23,HSPA1B,MAPK3,NEK1,UPF1,ATAD2,UBE2C,RPS6KC1,HIPK3 |
| 8.542e-07 | -13.97 | protein methylation | biological process | GO:0006479 | 135 | 43 | 17256 | 2622 |
RPS2,ASH1L,KMT2E,SUZ12,MECP2,CXXC1,NSD3,EZH1,RAB6A,SNRPD3,WDR5,RLF,TET3,IRF4,KMT5C,SUV39H2,KMT5A,PRDM4,ZNF335,CTR9,FBL,ARID4A,CARM1,HEMK1,BTG2,SNRPB,EHMT1,ARMT1,RTF1,WDR82,ICMT,MEN1,PRMT2,METTL22,KMT2C,KDM3A,DOT1L,SETD3,CAMKMT,OGT,KMT2B,PRMT7,BEND3 |
| 8.542e-07 | -13.97 | protein alkylation | biological process | GO:0008213 | 135 | 43 | 17256 | 2622 |
RPS2,ASH1L,KMT2E,SUZ12,MECP2,CXXC1,NSD3,EZH1,RAB6A,SNRPD3,WDR5,RLF,TET3,IRF4,KMT5C,SUV39H2,KMT5A,PRDM4,ZNF335,CTR9,FBL,ARID4A,CARM1,HEMK1,BTG2,SNRPB,EHMT1,ARMT1,RTF1,WDR82,ICMT,MEN1,PRMT2,METTL22,KMT2C,KDM3A,DOT1L,SETD3,CAMKMT,OGT,KMT2B,PRMT7,BEND3 |
| 8.550e-07 | -13.97 | cytoskeleton-dependent cytokinesis | biological process | GO:0061640 | 76 | 29 | 17256 | 2622 |
PLK1,PDCD6IP,RHOA,SEPT9,RHOC,ACTR3,ANK3,JTB,KIF23,SEPT8,RACGAP1,NUSAP1,CNTROB,AURKB,SEPT7,ANLN,STMN1,RHOB,RTKN,TMEM250,SEPT1,SNX18,RAB35,CEP55,SEPT11,CHMP4B,VPS4A,ESPL1,CFL1 |
| 8.550e-07 | -13.97 | MODULE_197 | MSigDB lists | MODULE_197 | 172 | 51 | 17377 | 2626 |
TCF12,EWSR1,FOXM1,KDM4A,PHB2,PTTG1,KIF23,CTCF,KIF2C,LANCL1,ZNF267,CCNB1,CCNA2,MTA1,YBX1,KIF22,KNTC1,CDC25B,CORO1A,CITED2,ATF2,DNMT1,PLK1,MYBL2,ILF3,E2F3,TBRG4,WDHD1,SMC2,MEF2D,CBFA2T2,SOX4,TXNL4A,ETS2,BIRC5,TULP3,TFDP1,E2F1,CEBPG,HMGB2,KPNA2,YY1,PPP5C,UBE2C,CCNB2,TERF1,CBX4,HDAC2,SSRP1,ADNP2,ZBTB24 |
| 8.550e-07 | -13.97 | GSE13547_CTRL_VS_ANTI_IGM_STIM_BCELL_2H_UP | MSigDB lists | GSE13547_CTRL_VS_ANTI_IGM_STIM_BCELL_2H_UP | 172 | 51 | 17377 | 2626 |
H2AFZ,CLSPN,KDM4A,FAM129A,CENPF,ANK3,CDCA3,RRM1,CDCA8,TPX2,NUF2,KIF2C,NCAPG,STMN1,LCLAT1,FBXO5,CCNA2,CLIC4,KIF14,PRC1,KIF22,MYO5A,ACSL5,PLK1,TGFB1,TRAFD1,CSRP1,ASPM,MTA2,RAD51AP1,MKI67,KIF15,RRM2,CCDC34,WDHD1,AURKB,BRCA1,KIF11,RPA1,PRIM1,POLE,NEIL3,STAT1,H2AFX,LY75,KPNA2,FKBP5,EHD4,GLCCI1,CCNB2,GEN1 |
| 8.595e-07 | -13.97 | mitochondrial ATP synthesis coupled electron transport | biological process | GO:0042775 | 80 | 30 | 17256 | 2622 |
COX15,COX5B,NDUFA5,NDUFV2,NDUFS1,NDUFB6,UQCR10,MECP2,NDUFA4,COX4I1,CYCS,NDUFA7,NDUFB1,TAZ,SDHA,NDUFS7,NDUFS4,NDUFV1,NDUFA2,NDUFB4,COX7A2L,NDUFA11,COX8A,COX5A,NDUFB9,NDUFS8,UQCRH,NDUFS5,CYC1,NDUFA3 |
| 8.600e-07 | -13.97 | REACTOME_INFLUENZA_VIRAL_RNA_TRANSCRIPTION_AND_REPLICATION | MSigDB lists | REACTOME_INFLUENZA_VIRAL_RNA_TRANSCRIPTION_AND_REPLICATION | 101 | 35 | 17377 | 2626 |
RPS15,RPS2,RPLP2,POLR2K,RPL15,RPL11,RPL23A,GTF2F1,RPL17,GRSF1,RPL19,RPL29,POLR2I,RPL35,POLR2L,POLR2G,POLR2D,RPL8,RPL38,RPL6,RPS10,RPS24,RPL27A,RPS9,POLR2A,RPSA,RPL36,RPL37,POLR2J,RPL32,RPS27A,RPS14,RPLP1,FAU,RPS26 |
| 8.601e-07 | -13.97 | GSE32034_LY6C_HIGH_VS_LOW_MONOCYTE_DN | MSigDB lists | GSE32034_LY6C_HIGH_VS_LOW_MONOCYTE_DN | 186 | 54 | 17377 | 2626 |
MIB2,CTDP1,SART1,PARP12,KIAA0100,AGRN,ZCCHC8,FAM207A,SEC61G,EIF3D,DLGAP4,UBE2Z,CHKB,CDK11B,PITHD1,RAPGEF6,FAM8A1,FBXO22,SEC11A,RRN3,EIF4A3,PPP1R8,AHSA1,POP7,UBA5,RRBP1,CRY2,GLE1,ATP6V0D1,NSUN4,CTDSP2,PPAN,NXT1,RBM42,DDX24,RNPS1,FRAT2,RAB3IP,TXNL4A,PSMB9,DHX57,HAUS8,HLA-B,DAP3,SAFB,AXIN1,STAT1,DCAF11,PDXK,CHMP7,TSTD2,RHEBL1,RNF114,PTOV1 |
| 8.601e-07 | -13.97 | GSE17721_POLYIC_VS_GARDIQUIMOD_6H_BMDC_DN | MSigDB lists | GSE17721_POLYIC_VS_GARDIQUIMOD_6H_BMDC_DN | 186 | 54 | 17377 | 2626 |
SRM,IER2,TMED7,TM9SF4,POLR2K,SEC61G,DNAJB2,SCYL1,TM9SF3,LETMD1,SLC4A2,SDHA,GNB2,PNO1,SEC11A,SNX18,AP3S2,NSFL1C,MRPL54,ANAPC7,UBE2M,TMX1,RNF5,USP34,AMPD2,MND1,ACP2,NUDT4,PGS1,BTG2,TEX10,CAMSAP1,JTB,GMFB,UBE2V1,BRCA1,VDAC1,CYFIP2,MRPS14,EIF4H,CCT8,DHX15,CYB5A,CCDC127,ABHD5,TTC13,HNRNPR,AEN,SAMD8,ASNA1,YY1,NMD3,POT1,PDCD4 |
| 8.601e-07 | -13.97 | GSE17721_POLYIC_VS_PAM3CSK4_4H_BMDC_DN | MSigDB lists | GSE17721_POLYIC_VS_PAM3CSK4_4H_BMDC_DN | 186 | 54 | 17377 | 2626 |
MMACHC,TMED7,TP53RK,PHB2,LAMTOR3,SLC4A2,SIRT2,RAB6A,PRPF39,TMEM165,FAM8A1,RBM4,FBXO22,SSR1,WRNIP1,C18orf32,SHC1,RALB,TIMM23,SNX18,SLC44A1,LTN1,SEPT11,UBE3C,ATF2,ABCC1,RBM15B,TMEM39A,PGS1,RDH10,CAMSAP1,RFFL,PLEC,MRPS14,MBD3,CCT8,EIF3A,HSPA1B,ADSS,DDOST,ORMDL2,SURF4,TPP2,E2F4,ACLY,H2AFX,CAB39,NUP62,CHMP7,HRAS,SLC25A33,HDAC2,VPS29,PDCD4 |
| 8.601e-07 | -13.97 | GSE22432_MULTIPOTENT_VS_COMMON_DC_PROGENITOR_UP | MSigDB lists | GSE22432_MULTIPOTENT_VS_COMMON_DC_PROGENITOR_UP | 186 | 54 | 17377 | 2626 |
RAB14,IMMT,PPCS,ATXN3,H2AFZ,NDUFAF2,MANBA,MUM1,GPR89A,MXD4,LCLAT1,RRN3,PSMD1,CCNA2,FBXL6,STRBP,UCHL5,RBM34,EXOSC1,SOCS6,BCAP29,KNTC1,NFU1,GLE1,PRADC1,TOP1MT,LRRC59,MTX2,NUP85,STRAP,FYTTD1,TDP1,PHF10,PRIM2,RAD51AP1,DHX29,RNPS1,PSMA1,DDX20,SEPT7,TARS,USP36,CLNS1A,PRIM1,GOLGA7,NIP7,CORO1C,TATDN2,CEP55,PPM1G,TCOF1,WDR76,GCSH,GPR89B |
| 8.601e-07 | -13.97 | GSE1448_ANTI_VALPHA2_VS_VBETA5_DP_THYMOCYTE_UP | MSigDB lists | GSE1448_ANTI_VALPHA2_VS_VBETA5_DP_THYMOCYTE_UP | 186 | 54 | 17377 | 2626 |
RMND5A,USP7,CHMP2A,CMAS,HLA-E,RAF1,KIF23,CDC42SE2,BCL2L1,MXD4,ORC1,OAT,FOXO3,MYEF2,PABPC4,MAN1A1,EEF2K,TMEM179B,NUS1,TNFAIP8,TIMM23,TBC1D14,ATP13A3,RAB4A,AXIN2,NAP1L4,FTSJ3,FAM171A1,PREB,CLCN3,PPP3CA,ASPM,EMB,RAB7A,GLO1,NFATC2,NFATC2IP,UTP3,ARPC1A,HAGH,TOLLIP,KDM3A,TFEB,FAS,ANKRD10,HSPB11,CDC16,ZHX1,PRDX3,ACADM,PSAP,TRAF5,EYA2,HIGD2A |
| 8.601e-07 | -13.97 | GSE24634_NAIVE_CD4_TCELL_VS_DAY7_IL4_CONV_TREG_DN | MSigDB lists | GSE24634_NAIVE_CD4_TCELL_VS_DAY7_IL4_CONV_TREG_DN | 186 | 54 | 17377 | 2626 |
TMEM106C,IMMT,C1orf112,DCTN2,TPX2,NIT2,KIF2C,BLM,ASXL2,POLR3K,MYL6B,CFLAR,BCAT2,FANCL,SNRNP25,FUT8,PPP4R1,PPCDC,PRC1,ANXA5,KNTC1,PDIA6,MYO5A,SMC4,PREB,GINS1,TDP1,MLEC,RFC3,ACP2,NASP,LAP3,KIF15,PSMA1,SLBP,RRM2,NUSAP1,NDUFA7,SLC25A5,STYXL1,DERL1,KEAP1,ATAD2,ORMDL2,BIRC5,NEIL3,NFIL3,DHTKD1,SLC16A1,NUP62,CCNB2,MAPK1,ESPL1,IFI16 |
| 8.627e-07 | -13.96 | HNRNPH2 (heterogeneous nuclear ribonucleoprotein H2) | protein interactions | 3188 | 115 | 40 | 17029 | 2761 |
MAX,CYLD,HNRNPUL2,C19orf25,CUL1,RBM4,CRKL,HNRNPA2B1,CLIC4,EIF4A3,TARDBP,CNN2,RBM12B,HNRNPM,SRPK2,STAU1,VHL,HNRNPF,GMFB,CUL3,ILF3,CIRBP,BRCA1,MCM2,MAK16,MATR3,CAND1,PDCD6,SYNCRIP,HNRNPH3,RBMX,FASTK,PQBP1,IARS2,DDX5,COPS6,PLOD3,ARRB2,HNRNPDL,SMURF1 |
| 8.741e-07 | -13.95 | PRPF4 (pre-mRNA processing factor 4) | protein interactions | 9128 | 140 | 46 | 17029 | 2761 |
SART1,SF3B1,OLA1,CERK,CHCHD2,USP39,APP,TUBGCP2,PARK7,GRK2,EFTUD2,KIFAP3,CDK12,ILKAP,CDC37,PRPF19,CCT2,SNRNP200,RBM42,RPS10,NARF,CUL3,LSM8,PRPF3,ATP5MF,TXNL4A,PATL1,CCT8,SF3A2,DHX15,SRSF1,DDX23,CAND1,PFDN5,RPL32,PFDN4,LSM6,DGCR8,PRPF4,SNRPG,FAU,SASS6,ARRB2,LTA4H,N4BP2L2,PRPF4B |
| 8.820e-07 | -13.94 | PSMD13 (proteasome 26S subunit, non-ATPase 13) | protein interactions | 5719 | 95 | 35 | 17029 | 2761 |
CYLD,ZCCHC8,STRN4,DHX9,PSMD9,KCMF1,UBLCP1,RAD23A,PTPN2,HNRNPA2B1,PSMD2,PSMD1,PSMA6,HUWE1,UCHL5,RAD23B,SRPK2,CDC5L,TXNL1,PSMA8,VHL,PSMB7,PSMA1,SLC25A22,BRCA1,PSMB9,ABCF1,PSMB3,PSMC4,MTHFD2,PSMD3,PSMD8,RBBP4,ECPAS,PSMC1 |
| 8.820e-07 | -13.94 | CCND2 (cyclin D2) | protein interactions | 894 | 95 | 35 | 17029 | 2761 |
NCOR2,ST13,TSC2,COPE,DCTN2,ATP5F1B,SNRPD3,CALM2,CDK5,RB1,AKAP8,CDKN1B,STRAP,S100A6,EIF5A,RBX1,PLEC,DNAJA1,SEPT7,H2AFV,API5,TRIM28,RPSA,CBX3,RPA1,PSMC4,PPP2CA,PFDN5,PSMD3,ASNA1,ACTB,PLOD3,CDK2,PSMC1,CDKN2A |
| 8.820e-07 | -13.94 | CLNS1A (chloride nucleotide-sensitive channel 1A) | protein interactions | 1207 | 95 | 35 | 17029 | 2761 |
MIF,PTMS,RPS2,CYLD,MDH2,UFC1,UBXN1,RAC1,RPL15,CSNK2A1,SNRPD3,USP5,RAD23A,PDCD10,EIF4A3,SEC24C,ATIC,CTPS1,OSTF1,PDIA6,PPA1,S100A6,RHOA,SNRPB,GAR1,EPB41,PPP2CA,TPD52L2,PDLIM1,LSM6,ACTB,SNRPG,PGAM1,SMURF1,ARRB2 |
| 8.921e-07 | -13.93 | THOC2 (THO complex 2) | protein interactions | 57187 | 99 | 36 | 17029 | 2761 |
USP7,SARNP,THOC1,SUZ12,DHX9,SLC4A2,RPA2,EIF4A3,MRPS27,UBE3C,MOB1A,CHTOP,ATP6V0D1,CAMK2G,FYTTD1,STAU1,MRPL12,COG1,BCLAF1,PKMYT1,FXR1,DDX39A,PLEKHF2,ZMYM3,RPA1,GNAS,MTMR3,SURF4,MRPL27,KBTBD7,KMT2B,ECPAS,TERF1,SMAD4,PDCD4,TMEM131 |
| 8.924e-07 | -13.93 | GSE37534_PIOGLITAZONE_VS_ROSIGLITAZONE_TREATED_CD4_TCELL_PPARG1_FOXP3_TRANSDUCED_UP | MSigDB lists | GSE37534_PIOGLITAZONE_VS_ROSIGLITAZONE_TREATED_CD4_TCELL_PPARG1_FOXP3_TRANSDUCED_UP | 163 | 49 | 17377 | 2626 |
ZBED3,NUP188,WDYHV1,DBF4,CSNK2A1,USP39,SLC29A1,PDCD7,PSMD9,TCF19,RNF103,MIS12,NUDT19,PDXP,DAD1,TRMU,RPF2,COPS7B,GLE1,ANKRD9,GM2A,TMX1,TERF2,SLC39A9,PLK1,TSPYL4,EID1,AACS,WDR18,UBE2V1,GLO1,EIF2A,FANCE,MFN2,MAN2A2,SDHB,GALNT2,HSPA4,FNTA,RAB24,ZDHHC7,CNOT6,ZRANB2,PPP6R2,NR2F2,TAF6,GCSH,DYNC1LI2,S100PBP |
| 8.963e-07 | -13.92 | MIF (macrophage migration inhibitory factor) | protein interactions | 4282 | 61 | 26 | 17029 | 2761 |
MIF,PDCD6IP,LAP3,WDYHV1,VHL,STRN4,TKT,LDHA,GORASP2,MCM2,SPR,PCBP1,CDC73,PARK7,CLNS1A,PDCD6,TIMM13,HINT1,UPF2,COPS6,NANP,CDK2,IGBP1,PABPC1,ANXA11,LDHB |
| 8.965e-07 | -13.92 | ARPC2 (actin related protein 2/3 complex subunit 2) | protein interactions | 10109 | 72 | 29 | 17029 | 2761 |
METTL1,UNK,ARHGAP17,PPP1R12A,LAP3,ACTR3,NSUN2,MYH9,KRAS,RANGAP1,CAPZA2,ANLN,ARPC1A,PRKACA,TMEM165,MTR,SH3GLB1,RPA1,RPA2,PFDN5,TPD52L2,WAS,UBE2Q2,CCP110,ARPC5,CAPZA1,TNPO3,CDK2,FUBP1 |
| 8.965e-07 | -13.92 | PLIN3 (perilipin 3) | protein interactions | 10226 | 72 | 29 | 17029 | 2761 |
MAX,RHOBTB3,RHOA,RPRD1A,DHPS,ADSL,PKMYT1,PKM,RAB1A,VDAC1,APP,NPLOC4,CLNS1A,SMAD2,EIF4A3,ATIC,DUT,UBA5,WDR4,RAD23B,PPA2,BTF3L4,TBPL1,ANP32A,LRSAM1,PDLIM5,IGBP1,PPA1,IMPA2 |
| 9.056e-07 | -13.91 | SMAD3 (SMAD family member 3) | protein interactions | 4088 | 360 | 94 | 17029 | 2761 |
MBD1,TCF12,USP7,MAX,TSC2,FOXM1,ANK3,DHX8,CUL1,SMARCA4,MAPK14,GIT2,APP,SF3B2,PHC2,SAP130,KDM2A,UCHL5,PIN1,GMEB1,PPP1R12C,NUP153,CORO1A,ATF2,STRAP,UBQLN4,AATF,RBX1,BRCA1,ERBIN,EPB41,HSPA4,SMAD2,EIF4ENIF1,CDC16,RBL1,E2F4,MAFK,AXIN1,HIPK2,ATXN2L,ACTB,NCOA1,DVL1,SMAD1,MAPK1,SMURF1,SMAD4,CSNK1D,PARD3,LRCH1,GGA1,VAV2,CTCF,SLC25A12,ETS1,FOXO3,LMNA,CFLAR,WWP2,PRDM4,TANK,AXIN2,YBX1,SS18L1,CITED2,PABPC1,CAMK2G,CSNK1G2,KAT2A,PSPC1,ZMYND11,PRKAR1B,PARP4,RIT1,ARID1A,MEN1,CDK11A,RPA1,HGS,CDC27,TFE3,PITX1,MED15,PML,PIAS2,KMT2B,DDX5,YY1,SNRNP70,ZMIZ1,CDK2,TOB1,FAM83G |
| 9.094e-07 | -13.91 | GSE24292_WT_VS_PPARG_KO_MACROPHAGE_DN | MSigDB lists | GSE24292_WT_VS_PPARG_KO_MACROPHAGE_DN | 191 | 55 | 17377 | 2626 |
TCF12,DNAJC2,DNMT3A,PNISR,PARP12,REPS2,MRPS15,EYA1,FAM129A,TMEM109,MED13L,KIF23,SLC35B2,DOCK11,ATP6V1B2,C19orf48,CRLF3,RAPGEF6,TMCC3,PCNA,AHSA1,PIK3IP1,TRIM14,TERF2,GINS1,ARHGAP17,GCC2,MAPRE2,PSPC1,DENND4C,OXR1,GTPBP4,DNAJC9,PLEC,OGFR,ZFAND5,APPL1,IRF5,ARHGAP15,HAUS8,GLOD4,TFEB,HHEX,GNA12,ORMDL2,WDR11,PRPS2,TBPL1,GLG1,TMEM219,PDXK,EHD4,CLN3,RUFY3,PDLIM5 |
| 9.162e-07 | -13.90 | GSE17721_CTRL_VS_LPS_12H_BMDC_UP | MSigDB lists | GSE17721_CTRL_VS_LPS_12H_BMDC_UP | 177 | 52 | 17377 | 2626 |
TOMM20,MRPL42,GNPDA1,TRIM11,TIA1,ZFYVE21,HAUS4,ATG2B,NANS,HCFC1R1,XPR1,RAP1A,PCNA,NDUFA2,IL6ST,BDH1,XPA,CS,ABCD1,TALDO1,FBL,ATP6V0D1,MED22,GPX4,ELOVL5,PPP3CA,RPL35,SEC61B,PBK,NUDT4,KIAA0930,SLC26A6,RPL6,FRAT2,TMEM147,VDAC1,RHOT2,SLC50A1,NEU1,GIGYF1,RXRB,HAUS8,TFEB,GNA12,H2AFX,ACAT1,ATF6,CTSA,TRIM32,NDUFS5,CENPT,CCNB2 |
| 9.179e-07 | -13.90 | HOFFMANN_LARGE_TO_SMALL_PRE_BII_LYMPHOCYTE_UP | MSigDB lists | HOFFMANN_LARGE_TO_SMALL_PRE_BII_LYMPHOCYTE_UP | 154 | 47 | 17377 | 2626 |
MCM10,DBF4,CDCA3,RRM1,KIF23,RACGAP1,KIF2C,SLC29A1,CCNB1,STMN1,MYEF2,CDKN2C,CCNA2,MCM5,DUT,PRC1,ANP32A,KIF22,DNMT1,SMC4,NUDC,TK1,RFC3,NASP,SNX2,LDHA,MKI67,WDHD1,RRM2,NUSAP1,AURKB,SMC2,ANLN,RPA1,PPP2CA,IDE,MTHFD2,RBL1,CDCA5,H2AFX,HMGB2,ANP32E,KPNA2,UBE2C,CCNB2,COIL,TUBB |
| 9.188e-07 | -13.90 | TP73 (tumor protein p73) | protein interactions | 7161 | 136 | 45 | 17029 | 2761 |
IER2,CDT1,AGO2,CUL1,CSNK2A1,CCNB1,UBE2I,PRKACA,RPL11,WWP2,RB1,MDM2,CCNA2,PIN1,RTCB,AHCY,TALDO1,N4BP2,BIRC3,ASPM,UBE4B,BRCA1,TRIM28,DDX23,AKAP1,PFDN5,SMAD2,DSN1,CHD3,HIPK2,RPS14,MED15,PML,RNF38,LRPPRC,TRIM32,FUS,SASS6,CDK2,HRAS,HIPK3,CABLES1,OAZ1,DDB1,HDAC2 |
| 9.193e-07 | -13.90 | Integrated Breast Cancer Pathway | WikiPathways | WP1984 | 154 | 48 | 5312 | 837 |
MAX,TSC2,NF1,MAP3K7CL,RAC1,CERK,SMARCA4,BLM,JAKMIP1,RB1,MDM2,RAP1A,CDC42,PTEN,PIK3R2,MSH2,BCL2,CDC25B,CREB1,NUP85,MSH6,PLK3,BAK1,PLK1,KRAS,BRCA1,ODC1,USP21,FADD,RHEB,TSC1,SMAD2,JAK1,HIPK2,E2F1,STAT1,PML,DHTKD1,XRCC3,STK11,CHEK2,ZMIZ1,FAU,SMAD1,MAPK1,CDK2,SMAD4,CSNK1D |
| 9.386e-07 | -13.88 | SMNDC1 (survival motor neuron domain containing 1) | protein interactions | 10285 | 31 | 17 | 17029 | 2761 |
PPAN,SNRNP200,EWSR1,RBM42,SF3B1,SNRPB,CUL3,KIF23,RACGAP1,PRPF3,NFATC2IP,SND1,SF3A2,SF3B2,RRBP1,MRM3,FDFT1 |
| 9.607e-07 | -13.86 | Transport of Mature mRNA derived from an Intron-Containing Transcript | REACTOME pathways | R-HSA-159236 | 75 | 30 | 10287 | 1696 |
SRSF11,FYTTD1,NDC1,CDC40,SARNP,NXT1,NUP188,THOC1,RAE1,SRSF6,RBM8A,RNPS1,NUP54,NUP155,SRSF5,DDX39A,NUP205,SRSF1,NUP210,EIF4A3,SRSF4,NUP107,NUP62,NUP153,SRSF3,CHTOP,NUP58,NUP85,AAAS,SEH1L |
| 9.618e-07 | -13.85 | GO_NEGATIVE_REGULATION_OF_PROTEIN_MODIFICATION_PROCESS | MSigDB lists | GO_NEGATIVE_REGULATION_OF_PROTEIN_MODIFICATION_PROCESS | 598 | 134 | 17377 | 2626 |
ZBED3,FGFR1OP,TSC2,UBN1,NF1,KDM4A,PPP1R15B,FAM129A,SIRT2,CCNB1,PPP1R16B,PARK7,PRNP,CALM2,CDK5,CDKN2C,PSMD1,NOC2L,CRY2,DNMT1,BAK1,PLK1,NCK1,PBK,GMFB,EZR,LRP5,BRCA1,SOX4,HHEX,RPS27A,PSMD8,LIMK1,SOCS4,OGT,ROCK1,DVL1,ARRB2,PSMC1,HDAC2,PDCD4,HSPH1,ZCCHC9,GMFG,DNAJB2,UBXN1,CIB1,RGS2,PSMD9,PSEN1,FKBP1A,TFAP4,RB1,FBXO7,MVP,SOCS5,ZMYND11,GTPBP4,GBA,PSMA1,KDM3A,ISG15,PSMB3,PSMC4,AKAP1,MASTL,MBIP,CDC27,DUSP3,CSK,NUP62,CDK2,CDKN2A,PPP1R37,ASH1L,FOXM1,LYN,DUSP22,PSMA6,PIN1,SOCS6,CDKN1B,TARDBP,ANAPC7,GPD1L,STRAP,CTDSP2,PDCL3,SNX25,CUL3,PSMB7,PKMYT1,DNAJA1,CDC23,PSMB9,SOCS7,PPP2CA,DNAJC10,CDC16,CORO1C,STK38,PSMD3,GADD45B,PPP5C,PARD3,TRIP12,MECP2,AKT1S1,MAD2L2,FBXO5,PTPN2,PSMD2,PTEN,H2AFY,TGFB1,PDPK1,TNFAIP3,PRKDC,PRKAR1B,ANAPC2,WDR81,MEN1,HSPA1B,LEMD2,SH3BP5,GPS2,PML,PPP1R11,NR2F2,PARP10,IGBP1,UBE2C,HIPK3,ANAPC4 |
| 9.625e-07 | -13.85 | RPL36 (ribosomal protein L36) | protein interactions | 25873 | 132 | 44 | 17029 | 2761 |
KARS,RPS15,COX15,RPS2,CYLD,MPHOSPH8,RPLP2,MECP2,RPL15,CUL1,APP,RPL11,RPL23A,RPL17,ZNF746,RPL19,RPL35,TRIR,GTPBP4,RNPS1,CUL3,RPL8,RPL38,RPL6,RPS10,RPS24,BRCA1,PRKRA,VDAC1,RPL27A,RPS9,DHX15,RPSA,CAND1,QARS,RPS14,RPLP1,CDK2,ARRB2,HNRNPDL,RPS26,ZC3HAV1,GPATCH4,DDX42 |
| 9.665e-07 | -13.85 | mitochondrial gene expression | biological process | GO:0140053 | 140 | 44 | 17256 | 2622 |
MRPL9,MTERF1,MRPL42,MRPS2,MRPS15,MRPL39,TWNK,MRPS26,FOXO3,MRPL19,GFM2,MRPL50,GATC,TRMU,MRPS27,MRPL34,MRPL54,MRPL40,MRPL48,MRPL21,MRPL11,MRPL32,MRPL57,HARS,NOA1,MRPL43,MRPL12,TUFM,MRPS10,TBRG4,MRPL16,NDUFA7,POLG2,MRPS14,MRPL2,DAP3,MRPL55,CHCHD1,MRPL27,IARS2,QRSL1,MRPL13,MRPL3,SLC25A33 |
| 9.708e-07 | -13.85 | condensed chromosome | cellular component | GO:0000793 | 219 | 60 | 18223 | 2701 |
ZNF207,NIFK,SKA3,NSMCE4A,HJURP,CDT1,CENPF,SMC6,CTCF,NUF2,KIF2C,PMF1,CCNB1,UBE2I,BLM,SPDL1,CSNK1A1,NCAPG,MEAF6,MIS12,SPAG5,ADD3,AHCTF1,SMC3,KMT5C,AKAP8,NUP107,H2AFY,KIFAP3,SS18L1,CENPM,KNTC1,NUP85,SEH1L,SMC4,PLK1,BRD4,MKI67,RANGAP1,SMC2,BRCA1,AURKB,SEPT7,PHF6,CENPU,CBX3,DSN1,FBXO28,BIRC5,NSMCE2,CDCA5,LRPPRC,H2AFX,BAZ1B,HMGB2,CENPT,RRS1,NDE1,XRCC4,CDK2 |
| 9.760e-07 | -13.84 | GSE2770_UNTREATED_VS_TGFB_AND_IL12_TREATED_ACT_CD4_TCELL_6H_UP | MSigDB lists | GSE2770_UNTREATED_VS_TGFB_AND_IL12_TREATED_ACT_CD4_TCELL_6H_UP | 182 | 53 | 17377 | 2626 |
PWWP2A,ZNF296,C9orf78,IMMT,ASH1L,DHPS,IVNS1ABP,WDYHV1,GLUD1,RLF,C19orf48,SNAPC4,TFRC,ARL6IP6,FBXL6,NOL11,UBA5,MECR,CYB5R1,CABLES2,MRPL32,MYO5A,POU2AF1,FYTTD1,TTPAL,RPP25,YTHDC1,C16orf72,POLK,DENND1B,TUFM,GORAB,DCLRE1C,KDM3A,SERP1,TTC33,DHX57,YIF1A,DNAJC10,ATP6V1D,CCDC86,CAMKMT,APPL2,ACAT1,CRCP,ZRANB2,SSNA1,FAM208A,RPS26,CPEB2,TERF1,GCSH,HIGD2A |
| 9.760e-07 | -13.84 | GSE17721_PAM3CSK4_VS_CPG_4H_BMDC_UP | MSigDB lists | GSE17721_PAM3CSK4_VS_CPG_4H_BMDC_UP | 182 | 53 | 17377 | 2626 |
NCOR2,TMBIM4,FAM207A,GNPDA1,TCF3,ANKH,LAMTOR3,GLUD1,SECISBP2,ARF1,TMEM165,SRXN1,FERMT3,ZKSCAN1,SIAH1,PELO,FAM89B,TNPO3,EIF5,TMEM14C,ADCY7,AMPD2,IFRD1,SEC61B,KLF10,NSDHL,PPP1R21,HNRNPF,PIP4K2C,RCOR1,UBE2V1,MEF2D,VDAC1,KDM3A,MAK16,MAT2A,SRSF1,NECAP2,TFEB,RBM25,MFAP1,HNRNPH3,APPL2,H2AFX,ATP6V0C,FAM126A,TMEM101,YY1,ZNF830,PPP5C,POT1,CPEB2,DDX42 |
| 9.760e-07 | -13.84 | ALCALAY_AML_BY_NPM1_LOCALIZATION_DN | MSigDB lists | ALCALAY_AML_BY_NPM1_LOCALIZATION_DN | 182 | 53 | 17377 | 2626 |
TMEM106C,MCM10,PLXNC1,REPS2,FOXM1,PTTG1,TPX2,KIF23,PXMP2,HMGN3,KIF2C,CCNB1,MAN1A1,KIFC1,CDKN2C,NUP210,CCNA2,SLC1A4,DUT,RAD23B,XPA,MECR,RBM3,MDFIC,CENPM,OGG1,TK1,RHOBTB3,SEPT9,GALC,GNG7,KIAA0930,MKI67,RRM2,ITM2A,CDC6,MCM2,CCNF,CYFIP2,SHCBP1,CHAF1A,RPA1,POLE,BIRC5,TFDP1,ACAT1,ASNA1,WDR62,NGLY1,UBE2C,CCNB2,NXT2,USP13 |
| 9.760e-07 | -13.84 | GSE25085_FETAL_LIVER_VS_ADULT_BM_SP4_THYMIC_IMPLANT_DN | MSigDB lists | GSE25085_FETAL_LIVER_VS_ADULT_BM_SP4_THYMIC_IMPLANT_DN | 182 | 53 | 17377 | 2626 |
FOXM1,WDYHV1,PMS2,CDCA8,BCAP31,EBP,RFWD3,OIP5,RPA2,TTC9C,NUP107,CNPY4,GTSE1,RPN2,KIF22,AHCY,IMPA2,SMC4,HP1BP3,NTPCR,EIF3L,PRIM2,HMGN5,FOPNL,RAD51AP1,WDHD1,NUP155,EIF2A,VKORC1,FXR1,C9orf40,BORA,NDRG3,EIF3H,KIF18A,ATAD2,POLE,UEVLD,NEIL3,STK38,ERGIC3,OAZ2,CEP55,NRM,H2AFX,C4orf46,MDH1,ANP32E,ACADM,CENPT,REEP4,TERF1,SLC25A39 |
| 9.760e-07 | -13.84 | GSE21670_TGFB_VS_TGFB_AND_IL6_TREATED_CD4_TCELL_DN | MSigDB lists | GSE21670_TGFB_VS_TGFB_AND_IL6_TREATED_CD4_TCELL_DN | 182 | 53 | 17377 | 2626 |
DDX58,FAM208B,REPS2,SCAMP3,GPBP1L1,KLHL21,SEC61G,TSC22D3,MUM1,MAGED1,NUP54,MYH9,EPN1,UBE2I,CRLF3,IL21R,ZNF518A,GFM2,HAUS2,RBM17,RAB8A,AHCTF1,ATIC,NSUN4,ILKAP,PACS2,DVL2,KCNAB2,KDM3B,CDKN2AIP,ORAI2,STAU1,ERF,WDR1,PPIE,NARF,CIRBP,ADRB2,NUTF2,AP4E1,GIGYF1,EPB41,NSA2,SERTAD2,MRPL55,RBM25,SAFB,E2F4,COX8A,PRPF4,BTF3,ANXA11,ZNF146 |
| 9.760e-07 | -13.84 | GSE22589_HEALTHY_VS_HIV_INFECTED_DC_UP | MSigDB lists | GSE22589_HEALTHY_VS_HIV_INFECTED_DC_UP | 182 | 53 | 17377 | 2626 |
TCF12,RAB14,DNAJC2,PRKAB1,PDCD6IP,PIGN,MAPRE1,SYS1,RRP15,MRPS2,MUM1,SCYL1,SIKE1,C19orf48,METTL3,TUBGCP2,SLC25A36,PA2G4,CLUAP1,UCHL5,BDH1,ZDHHC13,TAF5L,TARDBP,SPTSSA,KCNAB2,PRPF19,CSTF1,METTL1,PSPC1,GTPBP4,POLR2D,KCTD20,PPWD1,PITPNB,GAR1,MAK16,EIF3G,MAT2A,NAP1L1,TTLL4,HNRNPR,MEGF9,PRMT7,SLC16A1,RRS1,TFDP2,NGLY1,COIL,ATMIN,IPO4,DYNC1LI2,SVIP |
| 9.760e-07 | -13.84 | GSE16386_IL4_VS_IL4_AND_ROSIGLITAZONE_STIM_MACROPHAGE_6H_UP | MSigDB lists | GSE16386_IL4_VS_IL4_AND_ROSIGLITAZONE_STIM_MACROPHAGE_6H_UP | 182 | 53 | 17377 | 2626 |
PKP4,TRMT6,OLA1,NUP54,B4GALT1,AP3S1,ASXL2,STAM,RRP36,LIN9,GTPBP3,SEC11A,SNRNP25,LRRC8D,UCHL5,BANF1,BDH1,EXOSC1,MECR,RNASEH2A,TECR,SAP30L,CCAR1,KCNAB2,EEF1D,TIMM50,CSNK1G2,POLR2I,ASPM,PRKDC,MRS2,LDB1,GTPBP4,MRPL16,SMC2,METTL22,TARS,DNAJC10,ZNF777,POLE,RAD18,DGCR8,LUC7L3,ZC3H7B,DBI,H2AFX,ADAM9,WIPI2,SMPD4,PPP6R3,RRS1,SASS6,MZT2B |
| 9.824e-07 | -13.83 | WAKABAYASHI_ADIPOGENESIS_PPARG_BOUND_8D | MSigDB lists | WAKABAYASHI_ADIPOGENESIS_PPARG_BOUND_8D | 620 | 138 | 17377 | 2626 |
MIB2,PIGM,THOC1,TMEM109,PLXNA1,USP48,COMMD5,MBD4,TET3,RABGAP1L,IL6ST,HADHB,MAST2,ZNRD1,WDR41,PLK1,SP3,ZNF672,KLF10,SEPT9,EHMT1,GMFB,LNX2,WDR82,ARHGDIB,BRCA1,EAF2,GALNT7,DIDO1,SOX4,OPTN,AHNAK,BRD2,ATE1,ADAM9,STK11,GLCCI1,NUMB,PRPF38B,DNAJC5,PHB2,MUM1,EIF2AK4,PRPF18,RB1,VMP1,ARPC5,XPA,EI24,TIMELESS,MDFIC,KNTC1,GEMIN4,ALDH9A1,NAGPA,ABHD2,AACS,ZNF574,ABCF1,PI4K2A,AKAP1,GNAS,DCK,ACLY,RUVBL2,ACSF2,TOB1,PPP1R37,TRIM41,CYLD,STARD7,SAFB2,DUSP22,BCAP31,CHD1,ARL6IP6,TMEM69,DECR1,FBXL6,MTMR4,DUT,PPME1,LPIN2,PDIA6,SAP30,POLR2L,POLR2G,OAF,LRRC8A,PKMYT1,MEF2D,EDF1,AZI2,EML4,TMEM201,DUS3L,RBL1,DGCR8,HIPK2,RWDD4,RAD51D,ATXN7L2,EYA1,ZFP91,SHPRH,DCTN2,CCM2,MRI1,MYNN,MXD4,DCUN1D4,WWP2,KRI1,IRF4,ADD3,NDUFA2,ARHGEF2,ABCD1,CITED2,ORC3,ACP2,TK1,TNFAIP3,POLK,TMEM39A,TMEM126B,HELB,FBXO9,ARHGEF12,MARK2,PICALM,CHCHD6,ATP6V1D,KEAP1,MEGF9,YWHAH,PGAM1,FAF1 |
| 9.882e-07 | -13.83 | TCTN2 (tectonic family member 2) | protein interactions | 79867 | 275 | 76 | 17029 | 2761 |
NDUFA5,NDC1,DDX47,ABCA3,PIGQ,TOR1AIP1,GPR89A,TMEM109,AGPAT1,CLCC1,IKBIP,ABHD14A,BCAP31,SEC11A,C18orf32,ATP2A2,IMPAD1,RPN2,TAP2,CISD2,TECR,LMAN1,PDIA6,LRRC59,RHBDD2,WDR41,PTPRK,CLPTM1,ATP13A1,RAB7A,ESYT1,GALNT7,KRTCAP2,RAB1A,ALG3,DDOST,SURF4,ITGB1,DHFR2,RTN3,AAAS,HLA-E,TMX3,B4GALT1,SDF2L1,MFSD10,HLA-A,EBP,DDRGK1,PTPN2,RPN1,NUS1,VMP1,DAD1,ARF5,NDUFS8,TMEM8A,SGCB,NCOA2,TMX1,PREB,MLEC,TMEM39A,NSDHL,ACSL3,HLA-B,PLD3,MAGT1,OSBPL8,TMEM219,SPCS3,PLOD3,CHMP7,PTDSS1,APOL2,NXPE3 |
| 9.975e-07 | -13.82 | CEP250 (centrosomal protein 250) | protein interactions | 11190 | 238 | 68 | 17029 | 2761 |
NOP2,RPLP2,MAGED1,MOGS,MYH9,SNRPD3,SEC16A,ANKIB1,APP,RPL11,RPL23A,RAD23A,ZKSCAN1,PCBP2,PRPF19,EXOSC6,RPL35,HNRNPF,PRPF3,MRPS14,MBD3,TRIM28,RPS9,DHX15,GIGYF1,DDX17,DAP3,EIF4ENIF1,HNRNPR,RPS14,PRPF4,ACTB,TRIM32,TUBB,RPS2,CLSPN,MRPS2,AGO2,NUP54,DHX9,RPL15,VASP,HUWE1,ARHGEF2,RPL19,NAP1L4,FBL,PABPC1,N4BP2,HNRNPM,HP1BP3,FTL,DDX24,RPL8,RPL6,RPS10,MATR3,MAGED2,PCM1,LRPPRC,NUP62,DDX5,SRSF3,NDE1,RBBP4,SGF29,DDB1,ZC3HAV1 |
| 1.003e-06 | -13.81 | KEGG_HUNTINGTONS_DISEASE | MSigDB lists | KEGG_HUNTINGTONS_DISEASE | 159 | 48 | 17377 | 2626 |
NDUFA5,NDUFV2,COX5B,NDUFS1,NDUFB6,POLR2K,UQCR10,DCTN2,NDUFA4,CYCS,COX4I1,SDHA,NDUFS7,NDUFS4,NRF1,NDUFV1,NDUFA2,NDUFB4,AP2B1,NDUFB9,NDUFS8,CYC1,CREB1,CLTB,NDUFA3,DNAL4,DCTN1,POLR2I,POLR2L,POLR2G,POLR2D,VDAC2,RCOR1,NDUFA7,NDUFB1,VDAC1,SLC25A5,POLR2A,SDHB,POLR2J,COX7A2L,COX8A,TBPL1,COX5A,UQCRH,NDUFS5,AP2S1,HDAC2 |
| 1.011e-06 | -13.81 | V$E2F4DP1_01 | MSigDB lists | V$E2F4DP1_01 | 225 | 62 | 17377 | 2626 |
H2AFZ,CLSPN,ZCCHC8,TRMT6,RMI2,SMC6,STMN1,ASXL2,FBXO5,HNRNPA2B1,TFAP4,PCNA,SMC3,CD3EAP,FIZ1,MSH2,TRA2B,MRPL40,MCMBP,DNMT1,ARID4A,CDC5L,YTHDC1,SP3,ZNF524,NASP,APH1A,PRKDC,E2F3,ILF3,DNAJC9,RRM2,CDC6,NFATC2IP,PBRM1,PKMYT1,MCM2,H2AFV,APPL1,MAT2A,POLR2A,SRSF1,CBX3,CAND1,ATAD2,SYNCRIP,HNRNPR,RBL1,DCK,LUC7L3,ZNF367,PRPS2,MAPK6,KBTBD7,E2F1,AP1S1,NUP62,FKBP5,WDR62,SASS6,GEN1,PRPF4B |
| 1.018e-06 | -13.80 | DAZARD_RESPONSE_TO_UV_NHEK_DN | MSigDB lists | DAZARD_RESPONSE_TO_UV_NHEK_DN | 299 | 77 | 17377 | 2626 |
CCDC93,UBL3,GLT8D1,PNISR,KIAA0232,TMX4,STARD7,CUL1,SLC25A44,CCNB1,CHD1,BIRC2,PHC2,DST,TNFAIP8,RABGAP1L,KIF14,ADCY9,ATP13A3,NUP153,TAF5L,ATF2,TIPARP,VPS13B,SP3,SHOC2,NCK1,TLK1,MKI67,E2F3,SLBP,MTMR6,WDHD1,WDR82,DIDO1,KIF2A,CERS6,BAZ1B,RRS1,ZNF146,PPP1R12A,MECP2,CENPF,GNE,MED13L,CTCF,KIF23,FOXO3,SLC25A36,MBD2,XPA,FEM1B,AFF1,AHDC1,MAML1,PIKFYVE,LPCAT1,NCOA2,MSH6,SMC4,MORC3,CYTH1,ADRB2,CBFA2T2,KIF11,SERTAD2,KEAP1,BBX,LPCAT4,MEGF9,RBPJ,MAP3K5,NR2F2,ZMIZ1,CCNB2,N4BP2L2,ZBTB24 |
| 1.020e-06 | -13.80 | CLTC (clathrin heavy chain) | protein interactions | 1213 | 294 | 80 | 17029 | 2761 |
CYLD,RAC1,MYH9,CUL1,SLC35B2,AP1B1,ATP6V1B2,SEC16A,PRKACA,STAM,REPS1,EDC3,SHC1,PPME1,AP2B1,NDUFB9,TECR,CLTB,POC5,DCTN1,USO1,VDAC2,CUL3,ATP6V0A1,BRCA1,ERBIN,MCM2,VDAC1,ANLN,RAB5B,RPSA,ATP1A1,HSPA4,DDOST,MYO18A,CHMP4B,ARRB2,SMURF1,NUMB,UNK,NDUFS1,MAPRE1,PKP4,GGA1,PHB2,EPN1,GGA2,CSNK1A1,RAB11A,CDC73,SCYL2,XPR1,RPA2,RPN1,HUWE1,SEC24C,ZNF746,GTSE1,DCP1A,CYC1,MVP,ATP6V0D1,STAU1,TRAFD1,PARP4,MYBL2,TUFM,CAPZA2,ADRB2,PICALM,ISG15,CAND1,RPA1,HGS,PCM1,ATP6V1D,TFE3,QARS,EHD4,CDK2 |
| 1.022e-06 | -13.79 | regulation of response to DNA damage stimulus | biological process | GO:2001020 | 186 | 54 | 17256 | 2622 |
BCL2L12,MIF,NSMCE4A,TRIP12,THOC1,FOXM1,EYA1,BABAM1,DHX9,BCL2L1,TERF2IP,RFWD3,RPA2,ANKLE1,PCNA,BABAM2,CYREN,MDM2,TIGAR,KMT5A,PARPBP,AXIN2,FEM1B,TIMELESS,SPIDR,OGG1,RNF169,TERF2,PGAP2,ERCC1,RAD51AP1,HELB,MRNIP,ARMT1,MCL1,BCLAF1,UBE2V1,BRCA1,PTTG1IP,TRIM28,KLHL15,PARG,PML,CEBPG,H2AFX,DDX5,CHEK2,TRIM32,CLU,WDR76,SLF1,EYA2,SLF2,POLQ |
| 1.027e-06 | -13.79 | GSE6259_FLT3L_INDUCED_DEC205_POS_DC_VS_BCELL_DN | MSigDB lists | GSE6259_FLT3L_INDUCED_DEC205_POS_DC_VS_BCELL_DN | 150 | 46 | 17377 | 2626 |
ANXA6,TPX2,HMGN3,SND1,NCAPG,CDKN2C,NRF1,NUP210,SP100,MRPS27,DAPK1,CS,PRC1,AP1M1,H2AFY,COPS7B,KNTC1,TAGLN2,CORO1A,ALDH18A1,MYBL1,GTF2H2,N4BP2,GM2A,TACC3,SMC4,ABHD2,PRRC2A,ASPM,PBK,KIF15,HSDL1,KCTD20,ITM2A,PLEKHM3,GALK2,ANLN,KIF11,FBXO21,BIRC5,LY75,KLHDC4,AKNA,LTA4H,GEN1,AP2S1 |
| 1.027e-06 | -13.79 | GSE40274_CTRL_VS_FOXP3_AND_XBP1_TRANSDUCED_ACTIVATED_CD4_TCELL_UP | MSigDB lists | GSE40274_CTRL_VS_FOXP3_AND_XBP1_TRANSDUCED_ACTIVATED_CD4_TCELL_UP | 150 | 46 | 17377 | 2626 |
URB2,PDAP1,MRI1,SLC35B1,SNRPD3,SLC25A43,STMN1,SNAPC4,NUP205,ANKLE1,ERH,NRF1,PDXP,EXOSC7,AHSA1,DDX31,AHCY,CENPM,TMEM14C,NUDC,POLR2L,LAP3,HPDL,PBK,MKI67,ATXN1,CDCA2,MCM2,CCNF,PRIM1,DOT1L,PAF1,RAB18,MRPL55,E2F4,MAFK,NSMCE2,WDR4,CDCA5,DBI,PPP5C,CCNB2,ESPL1,PFKP,BYSL,SSRP1 |
| 1.034e-06 | -13.78 | GSE22103_UNSTIM_VS_LPS_STIM_NEUTROPHIL_UP | MSigDB lists | GSE22103_UNSTIM_VS_LPS_STIM_NEUTROPHIL_UP | 187 | 54 | 17377 | 2626 |
HIVEP3,RHOG,TP53RK,MAX,PHRF1,RHOC,PPP1R15B,CDK13,SECISBP2,UBE2I,EIF1B,PPP1R16B,ANKRD39,RGS1,NPLOC4,PIP5K1C,IRF4,NRF1,VASP,KLF16,NSRP1,ZNF639,DCP1A,ANXA5,AQR,SOCS5,ERCC1,ZDHHC18,ABHD2,ZFP64,MAPKAPK3,WDR1,USP42,GTPBP4,GFER,SF3A2,OPTN,AKAP1,IWS1,FAS,AMZ2,PPP2CA,KIF2A,ZNF282,BRWD1,CLK3,NIP7,GRIPAP1,AEN,FAM122A,BEND3,DNAJC30,ANAPC4,DEF6 |
| 1.034e-06 | -13.78 | GSE32423_MEMORY_VS_NAIVE_CD8_TCELL_DN | MSigDB lists | GSE32423_MEMORY_VS_NAIVE_CD8_TCELL_DN | 187 | 54 | 17377 | 2626 |
SEPHS2,RAB14,UBE2E2,ANKRD13D,PPP1R12A,AGRN,ZCCHC8,PMS2,CERK,GMCL1,SNN,AP3S1,STAM,PAIP1,MEAF6,SSR1,DTL,RFWD3,RB1,CD3EAP,SSBP3,PTPN11,DAPK1,BRI3,NUP153,PRADC1,MGAT5,GCC1,ARID4A,SEH1L,LDHB,KIAA0930,MAP4K4,E2F3,LACTB,RABIF,FRAT2,ITM2A,PRPF3,SOX4,APPL1,PTPRF,TSC1,BRWD1,TWSG1,ZHX1,MYO18A,KBTBD7,MEGF9,TRIM32,FBXL3,NANP,BRWD3,SMNDC1 |
| 1.034e-06 | -13.78 | GSE3982_MEMORY_CD4_TCELL_VS_TH1_DN | MSigDB lists | GSE3982_MEMORY_CD4_TCELL_VS_TH1_DN | 187 | 54 | 17377 | 2626 |
NDUFV2,TOR3A,RRM1,CDCA8,FLOT1,CSNK2A1,BLM,CFLAR,DTL,OIP5,IRF4,SNRNP25,PA2G4,ATP6V0B,ATP2A2,MCM5,PPCDC,MSH2,AKR1B1,TIMELESS,AP2B1,AHCY,RNASEH2A,LRRC59,GINS1,PPIF,CCT2,ERCC1,TIMP2,NASP,LAP3,IDH3A,PBK,MRPL12,VDAC2,RRM2,CDC6,DNAJA1,SMC2,NUTF2,VDAC1,MCM2,KIF11,RHOB,PAF1,RAD51C,MTHFD2,ORMDL2,MFAP1,ACOX1,H2AFX,CEBPG,GPI,MRPL13 |
| 1.034e-06 | -13.78 | GSE40277_EOS_AND_LEF1_TRANSDUCED_VS_GATA1_AND_SATB1_TRANSDUCED_CD4_TCELL_DN | MSigDB lists | GSE40277_EOS_AND_LEF1_TRANSDUCED_VS_GATA1_AND_SATB1_TRANSDUCED_CD4_TCELL_DN | 187 | 54 | 17377 | 2626 |
DDX58,INTS2,GMFG,B4GALT5,HAUS4,AP1B1,ITGB5,LYN,TMCC3,DTL,ADD3,MCM5,ZNHIT6,DDX31,TAF5L,CENPM,METTL9,RNF26,SLC35C2,F2R,FRMD8,MED22,POU2AF1,TSHZ1,TSPYL4,RAD51AP1,UTP15,LRRC8A,SLBP,TOR1AIP2,CDC6,BRCA1,SMC2,GALNT7,MCM2,MPG,SHCBP1,DDX39A,PDE3B,MAK16,ASF1B,MAN2A2,GALNT2,CDCA4,PDLIM1,BIRC5,RBL1,APPL2,WDR76,SRSF3,HEXA,COIL,CBX4,GPATCH4 |
| 1.034e-06 | -13.78 | GSE1448_CTRL_VS_ANTI_VBETA5_DP_THYMOCYTE_UP | MSigDB lists | GSE1448_CTRL_VS_ANTI_VBETA5_DP_THYMOCYTE_UP | 187 | 54 | 17377 | 2626 |
SLC12A7,RMND5A,USP7,DDX47,GOLIM4,GNPDA1,HLA-E,RAF1,TRIM11,KIF23,CTCF,CDC42SE2,BCL2L1,OAT,PIP4K2A,MAN1A1,BCAT2,TMEM179B,CRKL,FKBP1A,CLIC4,TNFAIP8,TIMM23,ATP13A3,ZNF326,RNASEH2A,LMAN1,EIF5,ASB6,ABCC5,CDC5L,LDHB,CLCN3,POLR2I,ASPM,EMB,MAP4K3,ARPC1A,TOLLIP,EPB41,ANKRD10,NAP1L1,CDKN2AIPNL,OSBPL11,ETS2,CLK3,PRDX3,DCK,WNT5B,MAP4,ACADM,PSAP,GALNT10,ATP6V0E1 |
| 1.034e-06 | -13.78 | GSE22886_TCELL_VS_BCELL_NAIVE_UP | MSigDB lists | GSE22886_TCELL_VS_BCELL_NAIVE_UP | 187 | 54 | 17377 | 2626 |
RHOG,CTDP1,LIME1,CASP6,KLHL21,SRGN,MOGS,SMARCA4,BTN3A1,DNAJB1,ABHD14A,PSMD1,EXOSC7,GRSF1,ARHGEF1,LPIN2,KIF22,TECR,TMEM8A,CITED2,MVP,PPP6R1,KCNAB2,TACC3,LDHB,NIPAL3,DDX28,TMEM115,RBM42,PBXIP1,SELPLG,MRPL12,ITM2A,RANGAP1,LY6E,PRMT2,MPG,ATP1A1,LTBP4,SCAP,PPM1G,BCL7C,USP20,CABIN1,FKBP5,B4GALT3,RRS1,ARRB2,PSMC1,NRBP1,RTN3,TOB1,DEF6,ADNP2 |
| 1.034e-06 | -13.78 | GSE43863_NAIVE_VS_MEMORY_LY6C_INT_CXCR5POS_CD4_TCELL_D150_LCMV_DN | MSigDB lists | GSE43863_NAIVE_VS_MEMORY_LY6C_INT_CXCR5POS_CD4_TCELL_D150_LCMV_DN | 187 | 54 | 17377 | 2626 |
SRM,DDX47,NDUFS1,ZCCHC9,AGRN,CHERP,SLC41A1,PDAP1,TRMT6,SND1,ERH,UBXN2A,MDM2,CBWD2,SAR1A,CD3EAP,MEA1,TPST1,CLCN6,MRPL34,DDX31,UBE3C,TOP1MT,SCYL3,POC5,SEH1L,MED22,NUDC,MLST8,CSTF1,DDX24,AACS,GTPBP4,LDHA,TBRG4,ABHD11,PRPF3,DNAJA1,LUC7L,MAK16,CCT8,C1orf122,BOLA3,TMEM41A,NAP1L1,TIMM13,PSMD3,TBL3,NFIL3,WDR4,MRPL27,SLC16A1,PDXK,TSPAN5 |
| 1.037e-06 | -13.78 | GSE7509_FCGRIIB_VS_TNFA_IL1B_IL6_PGE_STIM_DC_UP | MSigDB lists | GSE7509_FCGRIIB_VS_TNFA_IL1B_IL6_PGE_STIM_DC_UP | 173 | 51 | 17377 | 2626 |
SRM,UCK2,SLC25A12,NIT2,GYG1,CHAC2,SUPT7L,DUSP22,RAB11A,CPNE3,FKBP1A,MRPL50,PSMD2,RRN3,NFATC3,PSMD1,TIMM23,FIZ1,EFTUD2,AP2B1,GLTP,RNASEH2A,TTLL12,GNAI2,ZNRD1,NIPSNAP1,TXNL1,STAU1,EIF3L,RHOA,RFC3,FAM49B,LAP3,EMB,WDR1,AMD1,SMU1,TMEM147,ODC1,H2AFV,RHEB,GINS4,MAPK3,CAND1,NSF,DBI,KBTBD7,PPA2,PPP3R1,PRMT7,EHD4 |
| 1.038e-06 | -13.78 | GO_TRANSFERASE_COMPLEX_TRANSFERRING_PHOSPHORUS_CONTAINING_GROUPS | MSigDB lists | GO_TRANSFERASE_COMPLEX_TRANSFERRING_PHOSPHORUS_CONTAINING_GROUPS | 230 | 63 | 17377 | 2626 |
INTS2,POLA2,BCCIP,CCNC,CTDP1,PRKAB1,POLR2K,ZNF768,PRKAA1,CDK13,CCNL2,PRKACA,BECN1,POLR3K,CDC73,MAD2L2,GTF2F1,CCNK,RB1,MED10,INTS7,CD3EAP,INTS1,PIK3R2,CTR9,INTS12,ATG13,TAF5L,POLR1B,GTF2H2,ZNRD1,RPRD1B,PHKG2,CDK12,ERCC1,RPRD1A,POLR2I,POLR2G,KAT2A,POLR2L,RB1CC1,HELB,PRKAR1B,POLR2D,POLR3GL,RTF1,EDF1,PRPSAP1,ERC1,TWISTNB,POLR2A,TAF2,PAF1,POLE,POLR2J,PRDX3,TBPL1,CRCP,CAB39,TAF12,MAP3K5,CDK2,TAF6 |
| 1.039e-06 | -13.78 | PTCD3 (pentatricopeptide repeat domain 3) | protein interactions | 55037 | 80 | 31 | 17029 | 2761 |
NOL12,NIFK,STAU1,RBM42,MRPS2,MRPS15,SUZ12,RPL6,RFXANK,CUL3,LNX2,LUC7L,RBM38,CAND1,NSA2,DAP3,HGS,SYNCRIP,GRSF1,FAM3C,ZNF746,MRPS27,MPV17,TBPL1,H2AFX,TRMT10B,RRS1,SNRNP70,CCDC59,ZC3H3,LUC7L2 |
| 1.039e-06 | -13.78 | MORF_PPP2R5E | MSigDB lists | MORF_PPP2R5E | 81 | 30 | 17377 | 2626 |
SP3,DPM1,RAE1,RAF1,TOR1AIP1,RAC1,NKRF,NFATC2IP,RAB1A,PSEN1,PRPSAP1,RAB11A,PRPF18,SSR1,CYHR1,SMAD2,PDCD10,RALB,PARG,XPA,MEA1,TBPL1,DUSP11,PRPF4,CLN3,CPSF4,COIL,ATP6V0D1,MYL12B,SMNDC1 |
| 1.039e-06 | -13.78 | mitochondrial translation | biological process | GO:0032543 | 114 | 38 | 17256 | 2622 |
MRPL9,MRPL42,MRPS2,MRPS15,MRPL39,MRPS26,GFM2,MRPL19,MRPL50,GATC,MRPL34,MRPS27,MRPL54,MRPL40,MRPL48,MRPL21,MRPL11,MRPL32,MRPL57,HARS,NOA1,MRPL43,MRPL12,TUFM,MRPS10,MRPL16,NDUFA7,MRPS14,POLG2,MRPL2,DAP3,MRPL55,CHCHD1,MRPL27,IARS2,QRSL1,MRPL13,MRPL3 |
| 1.041e-06 | -13.78 | GAPDH (glyceraldehyde-3-phosphate dehydrogenase) | protein interactions | 2597 | 220 | 64 | 17029 | 2761 |
KARS,CYLD,TXN,DYNLL1,SLC2A1,OLA1,CUL1,CCNB1,APP,MDM2,PCNA,SIAH1,GOT2,PPME1,DUT,ATF2,GPD1L,CFL1,CHP1,CDC5L,CUL3,ATXN1,BRCA1,MCM2,GLOD4,PSMD3,PRDX5,ACTB,FUS,COPS6,PPP5C,ARRB2,MAPK1,POT1,TUBB,PPIB,EWSR1,TKT,PSEN1,CDC73,RPA2,MAT2B,MED8,HUWE1,MCM5,OSTF1,S100A6,NUDC,STAU1,TK1,TUFM,ADRB2,PKM,ISG15,PRDX1,CAND1,RPA1,SYNCRIP,MAP3K5,PGAM1,CD81,CDK2,TERF1,CDKN2A |
| 1.043e-06 | -13.77 | Transcription-Coupled Nucleotide Excision Repair (TC-NER) | REACTOME pathways | R-HSA-6781827 | 79 | 31 | 10287 | 1696 |
COPS8,USP7,ERCC1,HMGN1,RFC3,POLR2I,POLR2G,POLR2L,POLR2K,RBX1,POLK,XAB2,PPIE,POLR2D,RFC2,POLR2A,RPA1,RPA2,PCNA,POLE,POLR2J,RPS27A,XPA,COPS7B,TCEA1,AQR,COPS6,ZNF830,GTF2H2,DDB1,PRPF19 |
| 1.047e-06 | -13.77 | GO_RETROGRADE_VESICLE_MEDIATED_TRANSPORT_GOLGI_TO_ER | MSigDB lists | GO_RETROGRADE_VESICLE_MEDIATED_TRANSPORT_GOLGI_TO_ER | 77 | 29 | 17377 | 2626 |
KIF3B,TMED7,TMEM115,COPA,COPE,SCYL1,KIF15,KIF23,KLC1,RACGAP1,KIF2C,TMED3,RAB6A,RAB1A,KIF11,COPG2,ARF4,COPB2,KIF2A,KIF18A,SURF4,NSF,TMED10,ARF5,STX18,KIFAP3,KIF22,TMED2,KDELR1 |
| 1.047e-06 | -13.77 | REACTOME_REGULATION_OF_MITOTIC_CELL_CYCLE | MSigDB lists | REACTOME_REGULATION_OF_MITOTIC_CELL_CYCLE | 77 | 29 | 17377 | 2626 |
PLK1,PSMA8,PTTG1,PSMB7,PSMA1,CUL1,ANAPC2,AURKB,CDC23,CCNB1,PSMD9,PSMB9,PSMB3,PSMC4,FBXO5,PSMD2,PSMA6,CCNA2,CDC16,PSMD1,CDC27,RPS27A,PSMD8,PSMD3,ANAPC7,CDK2,UBE2C,PSMC1,ANAPC4 |
| 1.051e-06 | -13.77 | regulation of cellular response to stress | biological process | GO:0080135 | 672 | 148 | 17256 | 2622 |
NUP188,TXN,THOC1,PPP1R15B,UBQLN2,PARK7,PCNA,NUP210,CYREN,NEK6,PARPBP,NUP153,OGG1,SEH1L,MLST8,BAK1,PGAP2,ERCC1,NCK1,RAD51AP1,PBK,MRNIP,EZR,MCL1,UBE2V1,BRCA1,MAP3K4,AXIN1,CHEK2,CLU,SLF1,AAAS,PDCD4,SVIP,HSPH1,NSMCE4A,UBXN1,GADD45G,DHX9,CHCHD2,EIF2AK4,DNAJB1,NUP205,TIGAR,FBXO7,TIMELESS,MDFIC,NUP85,TERF2,RB1CC1,ZMYND11,OXR1,ARMT1,BCLAF1,KRAS,EIF2AK1,SYVN1,PTTG1IP,MAP2K2,FAS,PTPRF,TSC1,DUSP3,KLHL15,QARS,CEBPG,NUP62,MAP3K5,NUP58,CDKN2A,NDC1,KARS,ATXN3,FOXM1,BCL2L1,DUSP22,LYN,APP,BCAP31,TERF2IP,ANKLE1,MDM2,BABAM2,NUP107,SPIDR,DVL2,RNF169,HTRA2,CGAS,TAOK1,MAP4K4,NUP155,DNAJA1,EDEM2,TRIM28,RBL1,HIPK2,ARNTL,GADD45B,H2AFX,ATF6,TRIM32,MAPK1,EYA2,POLQ,USP13,TMEM33,MIF,BCL2L12,DNAJC2,TRIP12,RAE1,EYA1,BABAM1,NUP54,PAWR,AKT1S1,FOXO3,DNAJB9,PTPN2,RPA2,RFWD3,PDCD10,PTEN,KMT5A,FUT8,AXIN2,FEM1B,ARHGEF2,PTGES3,CAMK2G,HELB,PRKDC,MEN1,PRDX1,RPA1,HSPA1B,MAPK3,GPS2,PARG,PML,DDX5,WDR76,PSAP,IGBP1,SLF2,HIPK3,HRAS |
| 1.054e-06 | -13.76 | GSPT1 (G1 to S phase transition 1) | protein interactions | 2935 | 44 | 21 | 17029 | 2761 |
CCT2,BIRC3,SNX2,GSPT2,RBM8A,XIAP,ATXN1,KRAS,RTF1,BECN1,BIRC2,PABPC4,IDE,UPF1,DHX16,MCM5,RNASEL,ATP6V1C1,PABPC1,CDKN2A,SPTAN1 |
| 1.067e-06 | -13.75 | YWHAG (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma) | protein interactions | 7532 | 410 | 104 | 17029 | 2761 |
HNRNPAB,TSC2,RAF1,SDHA,GIT2,APP,PABPC4,EDC3,MIEF1,ATP6V0B,ZBTB21,CDKN1B,TRA2B,CDC25B,TP53BP2,ATF2,CFL1,SRSF10,PRPF19,CDC5L,CCT2,SNRNP200,CUL3,RNPS1,UBE2V1,NFATC2,MCFD2,MCM2,SHCBP1,ERC1,DHX15,CHAF1A,OPTN,DDX17,AFDN,CLK3,LUC7L3,TRIM32,PTPDC1,ARRB2,POT1,PARD3,TUBB,PRPF4B,PRPF38B,UNK,RPS2,EWSR1,PPP1R12A,SHPRH,FAM53C,RRM1,NKD2,KIF23,KLC1,RACGAP1,AKT1S1,THRAP3,NCKAP1,ATP5F1B,CDK11B,RAB11A,FOXO3,RAPGEF6,JAKMIP1,DTL,KIF5B,HUWE1,CENPJ,HDAC7,MCM5,PPIG,CTPS1,DCP1A,ARHGEF2,PABPC1,HNRNPM,LUC7L2,LDHB,SAMD4B,TNFAIP3,PRKDC,KIAA0930,GTPBP4,BCLAF1,CYFIP2,MARK2,TFEB,TSC1,MFAP1,TFE3,HMGB2,YWHAZ,ATP5F1A,SRSF3,PPP6R3,MAP3K5,NDE1,WDR62,CFAP20,CDK2,YWHAH,TERF1,SMARCD1 |
| 1.080e-06 | -13.74 | C15orf48 (chromosome 15 open reading frame 48) | protein interactions | 84419 | 120 | 41 | 17029 | 2761 |
NDUFA5,NDUFV2,IMMT,NDUFS1,NDUFAF2,UQCR10,MCCC1,TIMM21,CHCHD2,ATP5PF,NDUFS7,ABL2,NDUFV1,NDUFA2,NDUFB4,TIMM23,RAB35,NDUFB9,NDUFS8,APOOL,SLC25A1,TIMM50,NIPSNAP1,COA3,TIMM8B,COQ8A,TBRG4,NDUFA7,NDUFB1,ECH1,RDH11,STOML2,CHCHD3,IDE,NDUFA11,COX7A2L,COX8A,COX5A,SLC16A1,NDUFS5,PITRM1 |
| 1.080e-06 | -13.74 | ALDOA (aldolase, fructose-bisphosphate A) | protein interactions | 226 | 120 | 41 | 17029 | 2761 |
DYNLL1,SUZ12,SUMO2,TKT,COX4I1,FKBP2,ATP5PF,CDC73,BCAT2,NDUFS4,PCNA,HUWE1,AHSA1,DUT,CS,TNPO3,TAGLN2,LMAN1,TALDO1,ATF2,GPD1L,CARM1,IMPA2,KCNAB2,CFL1,SRPK2,GPX4,CUL3,LDHA,GLO1,ADRB2,BRCA1,PKM,MCM2,ISG15,H2AFX,FUS,LTA4H,CDK2,TERF1,TUBB |
| 1.085e-06 | -13.73 | GO_RNA_CATABOLIC_PROCESS | MSigDB lists | GO_RNA_CATABOLIC_PROCESS | 211 | 59 | 17377 | 2626 |
RPS15,RPS2,RPLP2,GSPT2,RBM8A,RPL15,THRAP3,PARN,PAIP1,PABPC4,PRPF18,CNOT3,EDC3,RPL11,RPL23A,CSDE1,EXOSC7,EIF4A3,RPL17,PPP1R8,PELO,EXOSC1,DCP1A,UPF2,RPL19,RNASEH2A,CNOT6L,PABPC1,RPL29,RPL35,EXOSC6,POLR2G,RNASEH2C,RPL8,RNPS1,RPL38,POLR2D,RPL6,RPS10,RPS24,EXOSC9,RPL27A,PATL1,RPS9,RPSA,RPL36,PPP2CA,RPL37,UPF1,RPL32,LSM6,RPS27A,RPS14,RPLP1,KHSRP,CNOT6,SMG9,FAU,RPS26 |
| 1.090e-06 | -13.73 | GSE29949_CD8_POS_DC_SPLEEN_VS_DC_BRAIN_UP | MSigDB lists | GSE29949_CD8_POS_DC_SPLEEN_VS_DC_BRAIN_UP | 192 | 55 | 17377 | 2626 |
SART1,PNISR,MUT,GORASP1,CENPF,KCTD17,KLHL18,MEF2A,NKRF,SLC4A2,REEP5,ATG4A,HERC3,ZNF428,RALB,LPIN2,PPP6C,TIMELESS,GTSE1,ATP6V0A2,CDC25B,CREB1,AHCYL1,SPTSSA,GNAI2,ALDH9A1,ABCC1,ERCC1,LRBA,ACSL3,MKI67,SEPT8,EXOSC9,DIDO1,KLF6,PDE3B,HAGH,MAT2A,DAPK3,UPF1,SMAD2,POLE,SCAP,OSBPL8,DCK,SNAP23,GOLGA8A,NFIL3,LY75,RRS1,MAPK1,TRAF5,ESPL1,TUBB,BYSL |
| 1.090e-06 | -13.73 | GSE17721_0.5H_VS_24H_PAM3CSK4_BMDC_UP | MSigDB lists | GSE17721_0.5H_VS_24H_PAM3CSK4_BMDC_UP | 192 | 55 | 17377 | 2626 |
SLC12A7,MBD1,USP7,PPIB,DNAJC2,NDUFA5,DNAJC5,RWDD1,HLA-E,MDH2,NIPA2,SND1,ATP6V1B2,GLRX3,MIEN1,MXD1,PIP5K1C,GTF2F1,PTPN2,FKBP1A,CAPN2,FARSA,RPN1,PA2G4,RRN3,ZBTB45,HOMER1,SMC3,ARPC5,ARF5,DUT,GRSF1,PELO,EI24,AXIN2,ALDH18A1,MVP,LYPLA2,EIF5A,ABHD2,ZFP64,EID1,IDH3A,SELPLG,HNRNPF,HEBP2,NFATC2IP,MRPL2,HSPBP1,TTC13,CSK,MFAP1,COX5A,ZFP90,YWHAH |
| 1.090e-06 | -13.73 | GSE7460_CTRL_VS_TGFB_TREATED_ACT_CD8_TCELL_UP | MSigDB lists | GSE7460_CTRL_VS_TGFB_TREATED_ACT_CD8_TCELL_UP | 192 | 55 | 17377 | 2626 |
SEPHS2,MMACHC,CORO7,MCM10,PLXNC1,GNPNAT1,SCAMP3,THOC1,DNAJB2,DYNLL1,MRI1,RAB23,KIF23,LANCL1,GYG1,ITGB5,PCBP1,PABPC4,OIP5,SHC1,GOT2,NUP107,KIFAP3,TAGLN2,CYC1,GEMIN4,CPSF4,LPCAT1,NUP85,RPAP3,SAMD4B,DDX28,GUK1,ZNF512,TLK1,POLR2D,UTP15,EMP3,FRAT2,PKMYT1,EIF3G,MAP3K4,SLC19A1,DAP3,AHNAK,DSN1,ELMO1,TFDP1,DNAJC17,TMEM159,PPP5C,PDCD2L,TSEN15,AAAS,SSRP1 |
| 1.090e-06 | -13.73 | GSE22886_NAIVE_BCELL_VS_DC_DN | MSigDB lists | GSE22886_NAIVE_BCELL_VS_DC_DN | 192 | 55 | 17377 | 2626 |
SEPHS2,RHOG,NCOR2,CTDP1,FEZ2,MRPS15,FAM129A,RHOC,SRGN,SDC2,ZFYVE21,MAN2B1,ZNF267,SLC25A44,TMEM165,MAN1A1,GNS,CDK5,PSMD1,TFG,CITED2,LRRC59,IMPA2,KDELR1,PPIF,KLF10,MAPKAPK3,DENND1B,NQO2,MTMR6,ATXN1,MAP7D1,RIT1,SMC2,VDAC1,MRPS14,NEU1,MKNK1,MTHFD2,RBM47,MFAP1,SNAP29,SEL1L,PPA2,MPV17,ARAP1,IMPDH1,EHD4,ZMIZ1,RNF14,ARRB2,YWHAH,PSMC1,RTN3,DDB1 |
| 1.099e-06 | -13.72 | regulation of cellular component organization | biological process | GO:0051128 | 2369 | 439 | 17256 | 2622 |
RAB14,FGFR1OP,PDCD6IP,TSC2,ADD1,ADAM10,HEXB,PLXNA1,CCNB1,PPP1R16B,MIEN1,PARK7,EEF2K,CDK5,CDKN2C,NEK6,RABGAP1L,RAB4A,DNM2,AP2B1,FNIP2,DNMT1,MLST8,BAK1,ERCC1,RHOBTB3,AKT2,MKI67,WDHD1,AURKB,CCNF,MCM2,SLC25A5,CBFB,ZMYM3,STOML2,IWS1,MAP3K4,WAS,MID1IP1,LIMK1,MAP4,MYO18A,OGT,TFDP2,ARRB2,SLF1,HDAC2,SLC25A33,SVIP,MAPRE1,GMFG,PHF23,RHOC,PRKAA1,KCTD17,PARN,PSEN1,CDC73,LMNA,SPAG5,JMY,CFLAR,DDX56,PDXP,SMC3,ARPC5,MEGF8,FBXO7,MSH2,PIKFYVE,TERF2,EIF5A,CYFIP1,IFRD1,WDR1,PIP4K2C,BCLAF1,EXOSC9,CAPZA2,ADRB2,CBFA2T2,FXR1,KDM3A,MAP2K2,SF3A2,CCT8,RHOB,XRCC5,PTPRF,SCARB2,SERTAD2,CSK,CSNK1G1,PPP3R1,ARAP1,CNOT6,RUFY3,PDLIM5,CDKN2A,ZNF207,RHOG,ANKRD27,RPS6KA1,RAF1,POC1A,CHD1L,PTTG1,RAC1,ACTR3,TMEM97,RMI2,TPX2,MYH9,TBC1D13,BCL2L1,PRKACA,STMN1,STAM,APP,MOAP1,TERF2IP,CRKL,RAB21,SH3BP1,RALB,TBC1D22A,TBC1D14,CDKN1B,MAVS,TP53BP2,CFL1,DCTN1,CCT2,CDKN2AIP,PSRC1,MKLN1,EID1,KAT7,MAP4K4,TAOK1,WBP2,CUL3,VDAC2,NUSAP1,PKMYT1,CDC23,TRIM28,PPP2CA,PEX5,CDC16,CHMP4A,CORO1C,NSMCE2,CBLN2,NCLN,TRIM32,GEN1,LRP8,CSNK1D,ATMIN,POU3F2,MECP2,FLOT1,TRAK1,CBLL1,IP6K2,HDGFL2,ETS1,RAB11A,MAD2L2,CAPN2,RPA2,CLIC4,HUWE1,PTEN,CENPJ,PTPN11,AXIN2,CNOT6L,CREB1,GTF2H2,SPTAN1,PPP3CA,ZFP64,KAT2A,TCTEX1D2,STRIP1,NEK7,NET1,LLPH,ANAPC2,RHOT1,MACF1,KIF11,MARK2,PICALM,SH3GLB1,RPA1,INF2,GNA12,KIF18A,LTBP4,PARG,STX18,MAPK6,TFDP1,PML,PARP10,BRWD3,YWHAH,ESPL1,ANAPC4,FAF1,DDB1,SNAPIN,NPHP4,SKA3,PLXNC1,AGRN,KMT2E,CSNK2A1,CDC42SE2,SIRT2,UBQLN2,RUFY1,BECN1,MAPK14,BIRC2,PRNP,DLG5,ZNF804A,ABL2,RAP1A,CDC42,ZNF639,ATG3,DPYSL2,NOC2L,ZFYVE27,MTPN,CARMIL1,CARM1,TACC3,CDC37,PLK1,SEPT9,RBX1,NCK1,TLK1,GMFB,EZR,CDC6,ARHGDIB,LRP5,BRCA1,EAF2,OGFR,ANLN,RAB5B,OPTN,DPYSL3,EPB41,PAF1,TBC1D17,BRWD1,GRIPAP1,ATXN2L,PQBP1,ADAM9,STK11,PIEZO1,CLU,ROCK1,DVL1,CHPT1,POT1,PSMC1,MYL12B,C2CD5,UBE2D3,TBC1D12,HJURP,GORASP1,PHB2,DNAJB2,CENPF,SDC2,CIB1,CTCF,CDK13,DNAJB1,NCKAP1,RGS2,DOCK11,CRLF3,APOPT1,LYAR,SUB1,RB1,VASP,CCP110,TIGAR,KIF13B,XPA,EI24,CAPZA1,ZNF335,CTR9,TENM3,BCL2,GLE1,KNTC1,ZRANB1,MCPH1,LRSAM1,CSNK1G3,PREB,ATP5IF1,LDB1,CAMSAP1,GBA,RTF1,SEPT7,ARPC1A,EIF4G2,DAPK3,ARHGAP15,CAND1,PSMC4,TSC1,GOLGA4,CDC27,NSMF,CDCA5,NUP62,YWHAZ,DNPH1,RUVBL2,EHD4,TMEM14A,ADNP2,USP7,WASF2,CHMP2A,CYLD,FEZ2,DYNLL1,SMARCA4,LYN,TWF2,MIEF1,HNRNPA2B1,RRN3,MDM2,PIN1,KIF14,AKAP8,PARL,CORO1A,LMAN1,CHTOP,SPIDR,HTRA2,DVL2,EBAG9,PPIF,ARHGAP17,UBQLN4,PPT1,RAB7A,WIPF1,NFATC2,BICD2,VDAC1,CHMP2B,USP36,IDE,SURF4,UHRF2,XRCC3,CHMP4B,SCARB1,GAS2,H3F3A,SMURF1,MAPK1,AP2S1,SMAD4,ABCA1,TMEM33,CTDP1,SMAP1,TRIP12,RAE1,CDT1,CDK2AP2,ARFIP2,ARF1,CDK11B,CSNK1A1,SCYL2,PIP4K2A,TFRC,FBXO5,KIF5B,NABP2,H2AFY,BRD7,ARHGEF2,ATG13,SS18L1,RNF5,MYO5A,TGFB1,CSNK1G2,PPP1R9B,ADAM17,RHOA,MIER1,ZMYM5,NDRG3,BORA,RHOT2,CDK11A,MAPK3,MFN2,HSPA1B,MTMR3,UPF1,ATAD2,PLAA,E2F1,KMT2B,UBE2C,HRAS,SLF2,TERF1,ZSWIM6 |
| 1.099e-06 | -13.72 | GO_CYTOSKELETON | MSigDB lists | GO_CYTOSKELETON | 1809 | 344 | 17377 | 2626 |
FGFR1OP,PDCD6IP,ADD1,XIAP,CNTROB,CCNB1,ANKRD23,KIFC1,CALM2,CDK5,ANKRD26,NEK6,DNM2,SUCLG2,FNIP2,MAST2,CDC25B,KCNAB2,PLK3,SGCE,AATF,NSUN2,KIF15,DDX20,TOPORS,AURKB,DIDO1,CCNF,MCM2,SLC25A5,RAB22A,CLNS1A,STOML2,KRIT1,WAS,MID1IP1,AHNAK,WDR11,KIF18B,RAD18,AXIN1,MAP4,MYO18A,PTPN7,TRAF5,AAAS,ANXA11,DDX58,HSPH1,MAPRE1,DHX9,KIF23,HAUS4,PSEN1,HAUS2,MYL6B,JMY,LMNA,SPAG5,CEP104,PDXP,SMC3,KLHL5,ARPC5,DAPK1,FBXL7,MVP,GNAI2,NUP85,ELL2,WDR1,SEPT8,MAP7D1,PLEC,CAPZA2,CCT8,MAP2K2,PSMB3,TWISTNB,FNTA,GOLGA2,PDLIM1,FAM83D,MDH1,NDE1,CDK2,PDLIM5,ALS2,ZNF207,KARS,TRIP10,IVNS1ABP,RAB11B,POC1A,RAC1,ACTR3,ANK3,OLA1,TPX2,MYH9,NIT2,BCL2L1,PRKACA,STMN1,APP,CLUAP1,MTA1,NUP107,NSFL1C,SEPT11,CEP63,RNF19A,RPRD1B,CFL1,DCTN1,CCT2,MAPRE2,PSRC1,CUL3,NARF,NUSAP1,EML4,SERP1,KIF2A,PPP2CA,CDC16,JAK1,HINT1,CCDC14,DGCR8,CORO1C,TRIM32,GEN1,XRCC4,LRP8,CSNK1D,TUBB,DYNC1LI2,PKP4,MZT1,FLOT1,IP6K2,IFT27,RAB11A,MAD2L2,NEIL2,JAKMIP1,CAPN2,ADD3,CLIC4,CENPJ,PRC1,AXIN2,GTSE1,CNN2,SGCB,IFT46,NCOA2,NUDC,SPTAN1,PDLIM2,STAU1,KAT2A,TACC1,NEK7,PARP4,JTB,RAB3IP,MACF1,KIF11,MARK2,SPPL2B,MYO1F,CBX3,YIF1A,NUCB1,KEAP1,KIF18A,TTLL4,CCDC6,LRPPRC,SSNA1,WDR62,IGBP1,ESPL1,BYSL,DEF6,NPHP4,SKA3,DNAJC24,KIF2C,SIRT2,CDC42SE2,MAPK14,MAP1LC3B,BIRC2,DST,ABL2,RAB8A,PCNA,SYNM,CDC42,DPYSL2,RCSD1,XRCC2,KIF22,RP2,MTPN,TACC3,RPP25,PLK1,SEPT9,PBXIP1,FOPNL,TMEM216,CKAP2L,EZR,CDC6,ARHGDIB,BRCA1,ANLN,STK17B,DPYSL3,EPB41,HSPB11,SEPT1,CHD3,PQBP1,ZNF268,ACTB,ROCK1,DVL1,VPS4A,SASS6,MYL12B,TMUB1,PPP1R12A,CENPF,CIB1,KLC1,RACGAP1,DTL,RB1,VASP,CCP110,KIF13B,CAPZA1,TIMELESS,KIFAP3,KNTC1,MCPH1,ATP6V0D1,CAMSAP1,PSMA1,SEPT7,ARPC1A,DAPK3,ZNF174,HAUS8,MASTL,EVC2,TSC1,PCM1,CDC27,ODF2,SLC16A1,NUP62,MYO9A,CCNB2,MZT2B,WASF2,CYLD,DYNLL1,SLC2A1,PMS2,TWF2,MEAF6,STRBP,WDR44,KIF14,CORO1A,ABI1,HTRA2,DNAL4,POC5,PRPF19,PPP1R18,BIRC3,TUBGCP5,WIPF1,NFATC2,BICD2,CLK3,CEP55,GAS2,REEP4,MAPK1,PARD3,RAD51D,SLC30A9,KIF3B,CTDP1,KLHL21,DCTN2,SCYL1,CDCA8,PAWR,MYO9B,NCAPG,CSNK1A1,TUBGCP2,FBXO5,SAC3D1,FERMT3,KIF5B,STARD9,MZT2A,KLHL20,SLC1A4,ARHGEF2,TTC17,FRMD8,MICAL3,MYO5A,PPP1R9B,ADAM17,RHOA,ASPM,RANGAP1,WDR81,SYMPK,TARS,MFN2,MAPK3,HSPA1B,NEK1,ATP6V1D,FAM110A,BIRC5,SNAP29,USP20,PKD2,PREPL,TERF1 |
| 1.100e-06 | -13.72 | CASP3 (caspase 3) | protein interactions | 836 | 180 | 55 | 17029 | 2761 |
NDUFS1,ATXN3,ADD1,CASP6,GORASP1,CAST,PTTG1,RAC1,XIAP,MEF2A,BLM,CDK11B,PSEN1,BECN1,LYN,BIRC2,APP,BCAP31,CFLAR,VAV1,RB1,MDM2,CDC42,AKAP8,BCL2,PTGES3,MAP3K14,SLC35A1,DCTN1,SOCS5,SPTAN1,SRP72,PPP3CA,USO1,BIRC3,RBX1,PRKDC,ARMT1,MCL1,ARHGDIB,UBE4B,BRCA1,EIF4G2,CDK11A,PICALM,NMT2,CDC27,BIRC5,GRIPAP1,PARG,STAT1,ROCK1,COPS6,IDH3B,CDK2 |
| 1.107e-06 | -13.71 | GSE1112_OT1_VS_HY_CD8AB_THYMOCYTE_RTOC_CULTURE_DN | MSigDB lists | GSE1112_OT1_VS_HY_CD8AB_THYMOCYTE_RTOC_CULTURE_DN | 178 | 52 | 17377 | 2626 |
BCL2L12,PPCS,CDC40,NDUFS1,MPHOSPH8,KIAA0100,PPP1R15B,MCCC1,CERK,TKT,CUTC,BZW2,LMNA,EEF2K,CDK5,HERC3,UTP18,MCM5,ETV6,TTC9C,RAB4A,MRPL34,FAM89B,SOCS6,AKR1B1,ACAD8,CNOT6L,PRADC1,CLTB,TMEM14C,NUP85,PDPK1,PHF10,SEPT9,EMB,FBXO9,NUP155,NUTF2,CDC23,PCGF1,ECH1,RDH11,RPA1,MRPL2,TXNDC16,VPS26B,CSK,TATDN2,DTX4,IMPDH1,PKD2,MAPK1 |
| 1.108e-06 | -13.71 | PUJANA_BREAST_CANCER_WITH_BRCA1_MUTATED_UP | MSigDB lists | PUJANA_BREAST_CANCER_WITH_BRCA1_MUTATED_UP | 54 | 23 | 17377 | 2626 |
SRSF11,RFC3,NASP,HMGN4,FOXM1,NCK1,RAD51AP1,ILF3,MYBL2,AURKB,MCM2,BLM,DDX39A,STMN1,SNRPA,RPA1,CDKN2C,MCM5,TFDP1,MSH2,DNMT1,SMC4,SRSF10 |
| 1.118e-06 | -13.70 | nuclear envelope reassembly | biological process | GO:0031468 | 18 | 12 | 17256 | 2622 |
ANKLE2,PPP2CA,CHMP2A,UBXN2A,UBXN2B,BANF1,NSFL1C,CHMP4B,VPS4A,REEP4,CHMP7,LMNA |
| 1.121e-06 | -13.70 | SCHLOSSER_SERUM_RESPONSE_AUGMENTED_BY_MYC | MSigDB lists | SCHLOSSER_SERUM_RESPONSE_AUGMENTED_BY_MYC | 102 | 35 | 17377 | 2626 |
NCOR2,PDAP1,TMEM109,CSNK2A1,TAF6L,RAD23A,CYHR1,NDUFV1,CYC1,AHCYL1,LPCAT1,UBE2M,KCNAB2,PRPF19,CLPTM1,ERCC1,RBM42,GUK1,JTB,NFATC2IP,AURKB,OGFR,CCNF,SYMPK,SF3A2,UBTF,HGS,MAP4,NUP62,CABIN1,STK11,RGL1,PPP5C,IDH3B,PURA |
| 1.139e-06 | -13.69 | MODULE_18 | MSigDB lists | MODULE_18 | 439 | 104 | 17377 | 2626 |
TMEM106C,POLA2,TCF12,NQO1,FOXM1,TOR1AIP1,PTTG1,SLC2A1,UCK2,TPX2,C5orf30,CSNK2A1,PTP4A3,GYG1,ORC1,CCNB1,STMN1,SSR1,KIFC1,CDKN2C,RAP1A,PCNA,CCNA2,SYNM,INTS1,AP1M1,NUP153,SLC26A2,DNMT1,OGG1,HTRA2,PRPF19,PLK1,COPS8,SGCE,RFC3,TIMP2,HMGN4,CDC123,MRPL12,GMFB,SLBP,HTATIP2,AURKB,PITPNB,NUTF2,PKMYT1,CADM1,ICMT,CCNF,MCM2,CHAF1A,TRAM2,HSPB11,ATP1A1,AGPAT2,IARS2,H2AFX,PPP5C,RPS26,GCLM,MAPRE1,RRM1,SLC4A2,TMED3,PMF1,ITGB5,TFRC,NUP205,SLC1A4,GTSE1,AHCY,TTLL12,LPCAT1,MSH6,TMX1,FDFT1,PHF10,TK1,PRKDC,ACSL3,ILF3,EMP3,ADSL,ARID1A,PLEC,ARPC1A,DDX39A,KIF11,ABCF1,FADD,IRF5,PSMC4,RPA1,CBX3,SYNCRIP,MAPK6,TFDP1,E2F1,CDK2,UBE2C,ESPL1,MRPL3,IFI16 |
| 1.149e-06 | -13.68 | DNA damage response, signal transduction by p53 class mediator | biological process | GO:0030330 | 85 | 31 | 17256 | 2622 |
PLK3,MIF,FOXM1,BTG2,USP10,BRCA1,CCNB1,SOX4,CNOT11,FOXO3,CNOT3,CNOT9,TFAP4,MDM2,PCNA,SP100,RPS27A,CENPJ,HIPK2,E2F4,TFDP1,E2F1,PML,CDKN1B,GTSE1,CNOT6,CHEK2,TFDP2,CNOT6L,CDK2,CARM1 |
| 1.151e-06 | -13.67 | PRDX5 (peroxiredoxin 5) | protein interactions | 25824 | 69 | 28 | 17029 | 2761 |
PTMS,PSRC1,PPT1,BABAM1,LDHA,NIT2,TOMM40,SPR,IFT27,STAM,PARK7,APP,GINS4,PRDX1,FERMT3,CAT,PEX5,HINT1,DUT,RAD23B,KHSRP,MDH1,ATF2,IGBP1,CFL1,SSSCA1,FUBP1,LDHB |
| 1.156e-06 | -13.67 | SEM1 (SEM1, 26S proteasome complex subunit) | protein interactions | 7979 | 137 | 45 | 17029 | 2761 |
INTS2,USP7,SUMO2,CUL1,POMP,SND1,UBQLN2,UBE2I,MAP1LC3B,PSMD9,SAC3D1,UBLCP1,RAD23A,PSMD2,PSMD1,PSMA6,INTS7,HUWE1,UCHL5,FBXO7,RAD23B,NSFL1C,LTN1,RPF2,UBE3B,UBE3C,RBM15B,TXNL1,UBQLN4,PRRC2A,NARF,PSMG1,KRAS,BRCA1,EIF3A,PSMC4,RPA1,TAF2,PSMD8,PSMD3,YY1,ECPAS,PSMC1,PRPF4B,DDX42 |
| 1.156e-06 | -13.67 | RPS27A (ribosomal protein S27a) | protein interactions | 6233 | 137 | 45 | 17029 | 2761 |
RPS2,CYLD,EWSR1,GGA1,DNAJB2,RPL15,DAZAP2,BLM,CDK11B,APP,CDC73,RPL11,RPL23A,HNRNPA2B1,MDM2,PTEN,RPL17,MCM5,RPL19,MAST2,PTGES3,STRAP,RHOA,NSUN2,RPL6,RPS10,WBP2,RPS24,CDC6,MCM2,MAK16,TARS,RPSA,ISG15,SMAD2,SYNCRIP,RPS27A,RPLP1,H2AFX,SMAD1,CDK2,ARRB2,SMURF1,RPS26,SMAD4 |
| 1.158e-06 | -13.67 | AGUIRRE_PANCREATIC_CANCER_COPY_NUMBER_DN | MSigDB lists | AGUIRRE_PANCREATIC_CANCER_COPY_NUMBER_DN | 221 | 61 | 17377 | 2626 |
CTDP1,HECA,CDC40,PPP1R12A,TMBIM4,GGA1,RPS6KA1,EIF3D,KCTD17,MYH9,RACGAP1,SNRPD3,DAZAP2,ATP6V1B2,STMN1,CCDC28A,PHC2,GNS,C12orf10,CLIC4,SH3BP1,SRSF4,GMEB1,SOCS6,MECR,JOSD1,LYPLA2,PDPK1,CCT2,CDKN2AIP,PHF10,AMD1,MFNG,HEBP2,DCTD,AMDHD2,GALNT7,PRMT2,PTTG1IP,TXNL4A,MAK16,HMGN2,DDX23,CAND1,PFDN5,ORMDL2,PIAS2,QRSL1,ATP6V0C,CHEK2,TAF12,MAP3K5,PPP5C,E2F2,YWHAH,PDSS2,APOL2,CCDC59,HDAC2,ADNP2,ZBTB24 |
| 1.168e-06 | -13.66 | ATP synthesis coupled electron transport | biological process | GO:0042773 | 81 | 30 | 17256 | 2622 |
COX15,COX5B,NDUFA5,NDUFV2,NDUFS1,NDUFB6,UQCR10,MECP2,NDUFA4,COX4I1,CYCS,NDUFA7,NDUFB1,TAZ,SDHA,NDUFS7,NDUFS4,NDUFV1,NDUFA2,NDUFB4,COX7A2L,NDUFA11,COX8A,COX5A,NDUFB9,NDUFS8,UQCRH,NDUFS5,CYC1,NDUFA3 |
| 1.172e-06 | -13.66 | Transport of Mature Transcript to Cytoplasm | REACTOME pathways | R-HSA-72202 | 87 | 33 | 10287 | 1696 |
NDC1,CDC40,SARNP,NUP188,THOC1,RAE1,SRSF6,RBM8A,NUP54,NUP205,NUP210,EIF4A3,SRSF4,NUP107,NUP153,CPSF4,CHTOP,NUP85,SEH1L,FYTTD1,SRSF11,NXT1,RNPS1,SLBP,NUP155,SRSF5,DDX39A,SYMPK,SRSF1,NUP62,SRSF3,NUP58,AAAS |
| 1.172e-06 | -13.66 | GSE25088_WT_VS_STAT6_KO_MACROPHAGE_UP | MSigDB lists | GSE25088_WT_VS_STAT6_KO_MACROPHAGE_UP | 169 | 50 | 17377 | 2626 |
CTDP1,PRKAB1,UBE2E2,ZNF496,RPS2,PARP12,TRAF7,PHB2,MANBA,TOR3A,UBXN1,RMI2,STARD7,CREBL2,COX4I1,SND1,PITHD1,ARID1B,HMG20A,SEC11A,GOLM1,CS,SEPT11,ANP32A,JOSD1,RPN2,TERF2,IFRD1,MND1,ZDHHC18,PTPN18,GALC,APH1A,ASPM,LDB1,RPS10,TMEM216,AURKB,ODC1,RXRB,HMGN2,NSA2,PPP2R5A,QARS,ERGIC3,COX7A2L,LRPPRC,SLC22A23,FAF1,HIGD2A |
| 1.172e-06 | -13.66 | DEBIASI_APOPTOSIS_BY_REOVIRUS_INFECTION_DN | MSigDB lists | DEBIASI_APOPTOSIS_BY_REOVIRUS_INFECTION_DN | 275 | 72 | 17377 | 2626 |
POLA2,AGRN,UBR2,ABCC10,MAGED1,SLC29A1,SEC16A,ABHD14A,NUP210,SYNM,ATP2A2,DPYSL2,INTS1,ADCY9,MARCH2,AQR,MGAT5,CTDSP2,GM2A,MAPRE2,SEPT9,CELSR2,MKI67,ATXN1,LRP5,BRCA1,OGDH,ESYT1,PRPSAP1,H2AFV,MAT2A,AHNAK,STAT6,MAP4,FTSJ1,STK11,CAPN1,GALK1,KIAA0100,TCF3,DHX9,MYO9B,GGA2,ITGB5,IFT27,TFRC,GNS,FGFR3,RIMS3,RRBP1,BDH1,SLC38A10,PCYT2,GNAI2,LPCAT1,MSH6,IMPA2,ADAM17,MLEC,MAPKAPK3,NSDHL,PARP4,FBXO9,PLEC,MEN1,PRMT2,ECH1,POLR2A,NCDN,PTPRF,PITPNA,CTSA |
| 1.173e-06 | -13.66 | PCBP2 (poly(rC) binding protein 2) | protein interactions | 5094 | 96 | 35 | 17029 | 2761 |
PPIB,CYLD,GNPNAT1,TIA1,CUL1,KIF2C,PCBP1,SCYL2,SF3B2,HUWE1,PIN1,ARF5,YBX1,TARDBP,MAVS,UBE2M,PABPC1,PCBP2,CDC5L,KAT2A,GBA,CUL3,ADRB2,BRCA1,MCM2,SNRPA,PHF6,ARF4,H2AFX,RUVBL2,SRSF3,FUS,CD81,CDK2,FUBP1 |
| 1.175e-06 | -13.65 | GSE37301_LYMPHOID_PRIMED_MPP_VS_CD4_TCELL_DN | MSigDB lists | GSE37301_LYMPHOID_PRIMED_MPP_VS_CD4_TCELL_DN | 183 | 53 | 17377 | 2626 |
TMEM41B,MAGED1,SUMO2,LAGE3,USP39,BTN3A1,NOTCH2,UBE4A,XPO7,CDIPT,AP3S1,PMVK,RMI1,WWP2,MAT2B,VAV1,SNRNP25,CLUAP1,INPP5A,MRPL34,PIGG,EFCAB11,NDUFS8,OSTF1,NFU1,PCYT2,MINPP1,GNAI2,KCNAB2,MYO5A,VOPP1,CSNK1G2,MAPKAPK3,PPT1,PARP4,E2F3,AMDHD2,NDRG3,USP21,CAND1,ANKZF1,ATAD2,IARS2,LPCAT4,E2F1,BCL7C,CCDC69,MRFAP1L1,MAP3K5,FAM208A,PURA,PDCD4,NXT2 |
| 1.175e-06 | -13.65 | GSE16450_IMMATURE_VS_MATURE_NEURON_CELL_LINE_DN | MSigDB lists | GSE16450_IMMATURE_VS_MATURE_NEURON_CELL_LINE_DN | 183 | 53 | 17377 | 2626 |
HIVEP3,KIF3B,NOP2,URB2,TMEM97,UCK2,PLAGL2,BCL2L1,BLM,CCNB1,C19orf48,POFUT1,CD320,DTL,OIP5,FARSA,DDX56,HOMER1,PA2G4,SUV39H2,SLC38A5,IMPAD1,TTLL12,GTF2H2,TIMM50,NUDC,METTL1,SNX8,PPAN,RFC3,HPDL,NUDT4,AMD1,ABCF2,POLR2D,TOMM40,C9orf40,RFC2,FANCE,NEU1,CHAF1A,UTP20,TIMM13,CCDC86,SLC25A19,SLC16A1,NCLN,NANP,PDCD11,ESPL1,LRP8,SSSCA1,PFKP |
| 1.175e-06 | -13.65 | GSE18893_CTRL_VS_TNF_TREATED_TREG_2H_UP | MSigDB lists | GSE18893_CTRL_VS_TNF_TREATED_TREG_2H_UP | 183 | 53 | 17377 | 2626 |
LYRM4,SLC41A1,RAC1,TRIO,STARD7,UBE2Q1,MEF2A,GMCL1,EZH1,USP48,S1PR2,RCOR3,KIAA1147,ABL2,CYHR1,HOMER1,BRPF3,SAR1A,MBD2,PIK3R2,ZNF260,YBX1,TTC4,APOOL,MTPN,SAP30L,CTDSP2,ARL5A,GPX4,PPIF,FYTTD1,GTF3C6,TSPAN31,MAP4K3,MCFD2,STX16,CBFB,PRPSAP1,RHOB,GNAS,CHD3,CERS6,TWSG1,HIPK2,HNRNPH3,BBX,ITGB1,PGRMC1,GLG1,CHPT1,PURA,ZMAT3,SMARCD1 |
| 1.175e-06 | -13.65 | GSE40273_GATA1_KO_VS_WT_TREG_UP | MSigDB lists | GSE40273_GATA1_KO_VS_WT_TREG_UP | 183 | 53 | 17377 | 2626 |
KARS,NDUFA5,GOLPH3L,TMEM184B,COPA,PRKCSH,TMEM41B,GPR89A,ZFYVE21,SLC35B1,DUSP22,NPLOC4,RPA2,EIF2S2,SLC1A4,IARS,ATP2A2,VMP1,TIMM23,GOT2,DAD1,SIVA1,BDH1,PPP6C,NDUFB9,OSTC,RNF26,IFT46,IMPA2,TMX1,ALDH9A1,PREB,CLPTM1,FTL,MLEC,ELL2,NUDT4,TMEM147,KRTCAP2,MRPS14,ASF1B,MASTL,DTWD1,MAGED2,SEC61A1,ORMDL2,CERS6,FTSJ1,AP1S1,ATF6,SPCS3,PSMC1,GPR89B |
| 1.199e-06 | -13.63 | microtubule-based process | biological process | GO:0007017 | 668 | 147 | 17256 | 2622 |
FGFR1OP,XIAP,AP3M2,CNTROB,KIF2C,CCNB1,BIRC2,DST,KIFC1,CDK5,NEK6,CDC42,AP3S2,DNAAF2,XRCC2,AP2B1,KIF22,TACC3,PLK1,PLK3,FOPNL,KIF15,EZR,AURKB,BRCA1,HSPB11,KIF18B,CHD3,AXIN1,E2F4,MAP4,MYO18A,CHEK2,DVL1,VPS4A,CLN3,SASS6,PPP1R12A,DNAAF5,CIB1,KIF23,KLC1,HAUS4,RACGAP1,RAB6A,HAUS2,COPG2,LMNA,SPAG5,CCP110,KIF13B,KIFAP3,MCPH1,TERF2,GCC2,CAMSAP1,MYBL2,MAP7D1,FXR1,BBS12,HAUS8,PCM1,GOLGA2,ODF2,SLC16A1,NUP62,NDE1,MYO9A,CDK2,BCCIP,ZNF207,NDC1,ATXN3,POC1A,DYNLL1,ACTR3,TPX2,MYH9,NUF2,STMN1,APP,KTN1,RAB21,CLUAP1,ABRAXAS2,KIF14,PIN1,CEP63,RNF19A,DNAL4,DCTN1,CHP1,PSRC1,BIRC3,INTS13,TUBGCP5,NUSAP1,BICD2,RAB1A,EML4,TMEM201,KIF2A,GOLGA8A,AP2S1,PARD3,DYNC1LI2,TUBB,CSNK1D,KIF3B,MZT1,MECP2,DCTN2,TRAK1,MYO9B,SPDL1,IFT27,AP3S1,RAB11A,TUBGCP2,SAPCD2,FBXO5,KIF5B,STARD9,CENPJ,PRC1,ARHGEF2,GTSE1,IFT46,MYO5A,RHOA,TACC1,NEK7,ASPM,RHOT1,RHOT2,KIF11,MARK2,MYO1F,KIF18A,BIRC5,LRPPRC,CCDC69,SSNA1,PKD2,WDR62,ESPL1,SNAPIN |
| 1.201e-06 | -13.63 | translational initiation | biological process | GO:0006413 | 141 | 44 | 17256 | 2622 |
RPS15,RPS2,RPLP2,EIF3D,AGO2,RPL15,EIF1B,RBM4,PAIP1,MCTS1,RPL23A,RPL11,EIF2S2,RPL17,RPL19,EIF5,PABPC1,EIF3L,RPL29,RPL35,DHX29,RPL6,RPL8,RPL38,RPS10,RPS24,EIF2A,RPL27A,EIF4G2,EIF4H,EIF3G,RPS9,EIF3A,RPSA,EIF3H,RPL36,EIF3K,RPL37,RPL32,RPS27A,RPS14,EIF2D,RPLP1,RPS26 |
| 1.219e-06 | -13.62 | V$E2F1_Q3 | MSigDB lists | V$E2F1_Q3 | 231 | 63 | 17377 | 2626 |
H2AFZ,CLSPN,ZCCHC8,TRMT6,RMI2,SMC6,ORC1,STMN1,ASXL2,FOXO3,TFRC,CNOT3,FBXO5,TFAP4,PCNA,SMC3,CD3EAP,SSBP3,FIZ1,MSH2,PDS5B,MCMBP,ANKHD1,DNMT1,ARID4A,YTHDC1,SP3,ZNF524,NASP,APH1A,ABCF2,E2F3,KIF15,ILF3,DNAJC9,RRM2,RTF1,CDC6,NFATC2IP,PKMYT1,NUTF2,MCM2,POLR2A,SRSF1,HMGN2,CAND1,TRIM47,ATAD2,HNRNPR,RBL1,GPS2,DCK,LUC7L3,ZNF367,NDUFA11,KBTBD7,E2F1,ATE1,NUP62,WDR62,RBBP4,SASS6,GEN1 |
| 1.233e-06 | -13.61 | GO_NUCLEOSOMAL_DNA_BINDING | MSigDB lists | GO_NUCLEOSOMAL_DNA_BINDING | 30 | 16 | 17377 | 2626 |
HMGN1,H2AFZ,HMGN5,HMGN4,MTA2,SMARCA4,HMGN3,MBD3,HMGN2,MBD2,H2AFY,ACTB,RBBP4,H3F3A,SMARCE1,HDAC2 |
| 1.240e-06 | -13.60 | GSE15930_NAIVE_VS_72H_IN_VITRO_STIM_IFNAB_CD8_TCELL_DN | MSigDB lists | GSE15930_NAIVE_VS_72H_IN_VITRO_STIM_IFNAB_CD8_TCELL_DN | 188 | 54 | 17377 | 2626 |
GALK1,SLC2A1,OLA1,TMEM97,KIF23,JMJD6,HAUS4,POMP,FKBP2,POLR3K,SPAG5,SNRNP25,DECR1,RPN1,NDUFV1,CLIC4,IARS,NVL,MCM5,SIVA1,PDS5B,PDCD2,ALDH18A1,DNMT1,MTX2,HDHD2,S100A6,TACC3,CARM1,FDFT1,SAP30,TRAFD1,PRIM2,TSPAN31,RAD51AP1,MKI67,NUSAP1,BRCA1,MCM2,ANLN,RFC2,TPD52L2,CDKN2AIPNL,MTHFD2,BIRC5,CCDC6,DCK,CRCP,NDUFS5,RBPJ,RNF14,PGAM1,HRAS,DDX52 |
| 1.251e-06 | -13.59 | HNRNPA2B1 (heterogeneous nuclear ribonucleoprotein A2/B1) | protein interactions | 3181 | 194 | 58 | 17029 | 2761 |
HNRNPAB,CUL1,CSNK2A1,ATP5F1B,LMNA,RPA2,PA2G4,BABAM2,PSMA6,SHC1,IARS,ABRAXAS2,HUWE1,MCM5,AHSA1,YBX1,RBM3,TARDBP,MCPH1,LDHB,CDC5L,STAU1,VHL,ABCF2,HNRNPF,CUL3,SREK1,BRCA1,ADRB2,SRSF5,MCM2,RPL27A,ABCF1,MATR3,FKBP3,SF3A2,PHF6,ISG15,RPA1,CAND1,TIMM13,TXNDC16,RPS27A,QARS,HNRNPH3,H2AFX,XRCC3,SRSF3,COPS6,SNRNP70,ARRB2,CD81,SMURF1,HNRNPDL,ZMAT3,HIPK3,DYNC1LI2,CDKN2A |
| 1.253e-06 | -13.59 | GO_ADENYL_NUCLEOTIDE_BINDING | MSigDB lists | GO_ADENYL_NUCLEOTIDE_BINDING | 1444 | 282 | 17377 | 2626 |
ABCC10,TAP1,DHX8,GLUD1,UBE2I,EEF2K,KIFC1,CDK5,NEK6,ATP13A3,PDS5B,SUCLG2,MAST2,PLK3,RHOBTB3,PBK,AKT2,MKI67,KIF15,DDX20,AURKB,SMC2,MCM2,RFC2,MAP3K4,MKNK1,KIF18B,LIMK1,MYO18A,RNASEL,LONP2,PFKP,DDX42,DDX58,HSPH1,RECQL,CHTF18,PRKAA1,TRIO,CERK,RRM1,DHX9,KIF23,TOP2B,EIF2AK4,DDX56,SMC3,MCM5,DAPK1,MSH2,PIKFYVE,PHKG2,CARS2,UBE2QL1,DDX28,MAPKAPK3,PGS1,DHX29,PIP4K2C,ABCF1,CCT8,MAP2K2,XRCC5,PI4K2A,EPRS,NSF,CSK,CSNK1G1,QARS,DCK,ACLY,MAP3K5,CDK2,NRBP1,ACSF2,KARS,ABCA3,TP53RK,RPS6KA1,RAF1,CHD1L,ACTR3,KIAA0232,OLA1,TPX2,MYH9,PRKACA,FLAD1,PRKD3,ATP2A2,UBA5,ADCY9,CLCN6,TAP2,CDK12,ADCY7,CCT2,ULK3,ATP13A1,TAOK1,MAP4K4,PFKFB3,GALK2,DNAJA1,PKMYT1,DHX57,MAT2A,DDX17,KIF2A,RAD51C,HSPA4,JAK1,HIPK2,CBWD1,PDXK,PPP5C,CSNK1D,DYNC1LI2,POLQ,PRPF4B,GALK1,IP6K2,BLM,PMVK,PIP5K1C,SRXN1,GATC,CBWD2,MAP3K14,TTLL12,UBE2M,MSH6,SMC4,PDPK1,TK1,GUK1,DDX24,NEK7,BMS1,DDX39A,KIF11,MARK2,MYO1F,KIF18A,TTLL4,MAPK6,ASNA1,DDX5,DDX52,DDX47,UBE2E2,ST13,YTHDC2,MCCC1,UBE2Q1,CSNK2A1,UBE2Z,ABCB10,KIF2C,MAPK14,PAPOLA,ABL2,EIF4A3,TRMU,XRCC2,KIF22,SRPK2,ABCC5,PLK1,LARS,SNRNP200,HARS,TLK1,CDC6,STK17B,DHX15,CHD3,IARS2,BAZ1B,QRSL1,STK11,ACTB,ROCK1,VPS4A,CHEK2,PSMC1,UBE2D3,SEPHS2,CDK13,THRAP3,CHKA,UBE2Q2,KIF13B,AHCY,ALDH18A1,N4BP2,CSNK1G3,ABCC1,NTPCR,AACS,ACSL3,MAP4K3,EIF2AK1,UBE4B,BBS12,DAPK3,MASTL,PSMC4,PRPS2,NLRC5,RUVBL2,MYO9A,EHD4,UCK2,PMS2,UCK1,SMARCA4,CHKB,ORC1,ATP6V1B2,TWF2,LYN,CHD1,FARSA,PDK2,IARS,NVL,KIF14,SCYL3,ACSL5,CLCN3,RAD54B,IDE,ATP1A1,DHX16,CLK3,FASTK,STK38,XRCC3,MAPK1,ABCA1,RAD51D,KIF3B,NADSYN1,SHPRH,TOR3A,SCYL1,GNE,SMC6,MYO9B,CDK11B,CSNK1A1,PIP4K2A,SCYL2,WRNIP1,KIF5B,FGFR3,STARD9,GART,ABCD1,DDX31,MYO5A,CAMK2G,CSNK1G2,PRKDC,BTAF1,HELB,ABCF2,ATP2C1,PRKAR1B,PNPLA8,CDK11A,TARS,MAPK3,HSPA1B,DDX23,NEK1,UPF1,ATAD2,UBE2C,RPS6KC1,HIPK3 |
| 1.254e-06 | -13.59 | GSE2770_TGFB_AND_IL4_ACT_VS_ACT_CD4_TCELL_2H_UP | MSigDB lists | GSE2770_TGFB_AND_IL4_ACT_VS_ACT_CD4_TCELL_2H_UP | 174 | 51 | 17377 | 2626 |
IER2,SMAP1,CKLF,ANKH,CUTA,CERK,KLF13,TOP2B,ATG2B,PARK7,PABPC4,TNFAIP8,STRBP,NDUFA2,RPL17,DAD1,ATP13A3,SLC35B4,GLTP,METTL9,TPCN1,PABPC1,EIF3L,SNRNP200,COQ10B,RPL6,RPS10,ITM2A,ATXN1,ARHGDIB,ESYT1,UBE4B,NDUFB1,DHX57,ADSS,HLA-B,PFDN5,SERF2,TMED10,RPS27A,QARS,HIPK2,ERGIC3,PRDX5,SPCS3,H3F3A,CHPT1,C11orf1,LTA4H,ATP6V0E1,SVIP |
| 1.255e-06 | -13.59 | GO_MITOTIC_DNA_INTEGRITY_CHECKPOINT | MSigDB lists | GO_MITOTIC_DNA_INTEGRITY_CHECKPOINT | 94 | 33 | 17377 | 2626 |
CLSPN,TOP2B,CCNB1,BLM,FANCI,CNOT3,RFWD3,RPA2,MDM2,PCNA,CCNA2,CENPJ,MSH2,GTSE1,CDKN1B,CNOT6L,ATF2,CARM1,PLK3,BTG2,PRKDC,SOX4,RBM38,RPS27A,E2F4,TFDP1,E2F1,PML,CNOT6,CHEK2,ZNF830,TFDP2,CDK2 |
| 1.269e-06 | -13.58 | REACTOME_MRNA_SPLICING_MINOR_PATHWAY | MSigDB lists | REACTOME_MRNA_SPLICING_MINOR_PATHWAY | 40 | 19 | 17377 | 2626 |
SNRNP200,POLR2I,POLR2G,POLR2L,POLR2K,SF3B1,SNRPB,SRSF6,POLR2D,SNRPD3,TXNL4A,POLR2A,SRSF1,GTF2F1,DDX23,SF3B2,POLR2J,EFTUD2,SNRPG |
| 1.269e-06 | -13.58 | GO_CYTOPLASMIC_TRANSLATION | MSigDB lists | GO_CYTOPLASMIC_TRANSLATION | 40 | 19 | 17377 | 2626 |
RPL29,RPLP2,CDC123,EIF3D,GSPT2,RPL6,RPL8,RPL15,EIF4H,RBM4,EIF3A,RPL36,MCTS1,MRPL2,EIF2D,RPLP1,FTSJ1,RPL22L1,PCBP2 |
| 1.286e-06 | -13.56 | KYNG_WERNER_SYNDROM_AND_NORMAL_AGING_DN | MSigDB lists | KYNG_WERNER_SYNDROM_AND_NORMAL_AGING_DN | 212 | 59 | 17377 | 2626 |
KARS,THOC1,FOXM1,PDAP1,MED13L,BECN1,PSEN1,STAM,PDXDC1,WDR48,KIF5B,ZNF449,DAD1,CAPZA1,PPP6C,CNN2,SLC35A1,GM2A,MED22,MORC3,ADCY7,USP34,METTL1,CCT2,CYTH1,CYFIP1,USO1,DPM1,BAZ2A,GALC,CDC123,DRAP1,LRBA,HNRNPF,METTL2A,RNPS1,ATP6V0A1,EIF2AK1,ARHGDIB,RIT1,MCFD2,MCM2,ARPC1A,POLR2A,SRSF1,CBX3,DDX17,MTMR3,NUCB1,VEZF1,CDC27,HINT1,POLR2J,PFDN4,STK38,H3F3A,TFDP2,CABLES1,PTOV1 |
| 1.287e-06 | -13.56 | PSME3 (proteasome activator subunit 3) | protein interactions | 10197 | 172 | 53 | 17029 | 2761 |
CASP6,FLYWCH2,TRMT6,MYH9,RPL15,ATP5F1B,UBE2I,SRRT,SNAPC4,WDR48,GTF2F1,SF3B2,FAM192A,UTP25,PSMD2,MDM2,PSMD1,CMSS1,PSMA6,STRBP,ZKSCAN1,HUWE1,FBXO7,ARHGEF2,CDC25B,AHCYL1,FBXL19,ZCCHC10,PSMA8,PCGF6,GTPBP4,RNPS1,PSMA1,BRCA1,EAF2,PSMB9,LUC7L,PSMB3,PFDN5,MBIP,AHNAK,SERF2,RAD18,CLK3,PSMD8,PML,CCDC69,CHEK2,SMURF1,COIL,CBX4,PARD3,CDKN2A |
| 1.303e-06 | -13.55 | GSE8921_UNSTIM_0H_VS_TLR1_2_STIM_MONOCYTE_12H_UP | MSigDB lists | GSE8921_UNSTIM_0H_VS_TLR1_2_STIM_MONOCYTE_12H_UP | 193 | 55 | 17377 | 2626 |
MCM10,RWDD1,NF1,PRKCSH,C1orf112,MRPL39,UQCR10,ORC1,SPAG5,KIFC1,OIP5,LYAR,NRF1,UTP18,CENPJ,DNAAF2,DUT,JAZF1,SLC35B4,MSH2,NDUFB9,CYB5R1,TECR,GTF2H2,NUP85,B3GALT6,TIMM8B,PTPN18,PRIM2,LONRF3,LAP3,DHX29,GTPBP4,MRPS10,SSR2,PSMG1,NUSAP1,NDUFA7,DDX39A,KIF11,FOXRED1,PSMB3,RPA1,CHCHD3,HINT1,U2SURP,NAGLU,C4orf46,PRMT7,WDR76,WDR62,CDK2,HEXA,ESPL1,ZC3HC1 |
| 1.303e-06 | -13.55 | GSE27786_BCELL_VS_NEUTROPHIL_UP | MSigDB lists | GSE27786_BCELL_VS_NEUTROPHIL_UP | 193 | 55 | 17377 | 2626 |
GOLPH3L,ST13,SYS1,ANXA6,CXXC1,SRSF6,HEXB,MCCC1,DNAJC24,NKRF,SLC29A1,THRAP3,CNTROB,INO80E,METTL3,POLR3K,PDXP,NFATC3,CLIC4,EFTUD2,GEMIN6,H2AFY,MAVS,PIK3IP1,APOOL,ALDH18A1,SGCB,RBM15,CCAR1,RLIM,USP34,JMJD4,SRSF11,DDX24,FAM172A,CIC,NOL8,MRS2,MRPL12,RAB3IP,PRPSAP1,LUC7L,TRIM28,EIF3A,POLR2A,SOCS7,VEZF1,ZNF777,LUC7L3,ARNTL,PPM1G,COIL,GCSH,ALS2,RHEBL1 |
| 1.303e-06 | -13.55 | GSE22886_IGM_MEMORY_BCELL_VS_BLOOD_PLASMA_CELL_DN | MSigDB lists | GSE22886_IGM_MEMORY_BCELL_VS_BLOOD_PLASMA_CELL_DN | 193 | 55 | 17377 | 2626 |
GLT8D1,LIME1,GOLPH3L,TM9SF4,MRPS15,POLR2K,TCF3,UCK2,CERK,RRM1,TM9SF3,CSNK2A1,MXD4,TMEM165,PDXDC1,ABHD14A,WRB,FBXO5,GNS,CALM2,CDK5,DECR1,CLIC4,IL6ST,FUT8,RRBP1,PDS5B,ALDH18A1,UBE2M,MSH6,RPAP3,CLPTM1,COPS8,BAK1,AGGF1,TIMP2,MLEC,LAP3,CDC123,AACS,RAD51AP1,SSR2,CADM1,PDHX,PSMC4,ALG3,EPRS,GALNT2,SERF2,TIMM17A,CTBS,COPS6,NRBP1,DDB1,HDAC2 |
| 1.303e-06 | -13.55 | GSE2770_UNTREATED_VS_IL12_TREATED_ACT_CD4_TCELL_2H_UP | MSigDB lists | GSE2770_UNTREATED_VS_IL12_TREATED_ACT_CD4_TCELL_2H_UP | 193 | 55 | 17377 | 2626 |
RAF1,TMX4,AGPAT1,DLGAP4,ASAH1,MYH9,IRF3,DNAJB1,CDIPT,OAT,CPNE3,RPL11,ADD3,SIVA1,INTS1,CS,TPST1,ATP6V0A2,ANP32A,TAGLN2,STAT3,MYO5A,VPS13B,SPTAN1,CLPTM1,RPL29,ABHD2,TIMP2,PBXIP1,PRKDC,RPL38,GBA,RTF1,KCNQ1,SRSF5,MPG,EIF4G2,NEU1,RPA1,GNAS,CAT,MAN2A2,TAF2,NAP1L1,JAK1,SCAP,LSM6,OSBPL8,TATDN2,PRPS2,MEGF9,FKBP5,MAP3K5,TOB1,PTOV1 |
| 1.307e-06 | -13.55 | Rcc1 (regulator of chromosome condensation 1) | protein interactions | 100088 | 62 | 26 | 17029 | 2761 |
NDC1,RPS2,NUP188,RAE1,SUMO2,RANGAP1,NUP155,CDCA2,CHMP2B,UBE2I,RAB11A,NUP205,NEU1,DECR1,KPNA4,NUP210,HPS5,NUP107,NUP153,AFF1,KPNA2,H3F3A,FBXL19,NUP85,AAAS,SEH1L |
| 1.308e-06 | -13.55 | GO_REGULATION_OF_CYTOSKELETON_ORGANIZATION | MSigDB lists | GO_REGULATION_OF_CYTOSKELETON_ORGANIZATION | 472 | 110 | 17377 | 2626 |
WASF2,ZNF207,CHMP2A,SKA3,CYLD,PDCD6IP,ADD1,RAC1,ACTR3,XIAP,TPX2,MYH9,SIRT2,CCNB1,TWF2,BECN1,STMN1,BIRC2,KIFC1,ABL2,CDK5,NEK6,CDC42,CDKN1B,CORO1A,CEP63,MTPN,MLST8,PLK1,PSRC1,BIRC3,NCK1,TAOK1,TUBGCP5,GMFB,WIPF1,EZR,ARHGDIB,AURKB,BRCA1,CCNF,CHMP2B,KIF2A,MID1IP1,WAS,CHD3,LIMK1,MAP4,XRCC3,CHMP4B,ROCK1,CHEK2,GEN1,MAPK1,CSNK1D,TUBB,KIF3B,MAPRE1,GMFG,DCTN2,CIB1,KIF23,ARFIP2,RACGAP1,HAUS4,NCKAP1,ARF1,RGS2,RAB11A,HAUS2,TUBGCP2,JMY,SPAG5,FBXO5,CAPN2,STARD9,PDXP,VASP,CLIC4,SMC3,ARPC5,CENPJ,CAPZA1,PRC1,ARHGEF2,SPTAN1,TGFB1,CYFIP1,RHOA,ASPM,NEK7,WDR1,MYBL2,CAPZA2,BORA,ARPC1A,KIF11,MARK2,DAPK3,MAPK3,HAUS8,TSC1,KIF18A,GOLGA2,BIRC5,ARAP1,WDR62,ESPL1,HRAS,TERF1 |
| 1.314e-06 | -13.54 | GO_REGULATION_OF_RNA_SPLICING | MSigDB lists | GO_REGULATION_OF_RNA_SPLICING | 90 | 32 | 17377 | 2626 |
YTHDC1,RBM42,AKT2,SRSF6,RBM8A,RNPS1,HNRNPF,TIA1,JMJD6,THRAP3,RBM4,RBM38,POLR2A,HNRNPA2B1,AHNAK,RBM25,NSRP1,CLK3,FASTK,RBMX,SRSF4,PQBP1,TRA2B,DDX5,SRSF3,SNRNP70,RPS26,CDK12,SRSF10,RBM15B,PRPF19,SRPK2 |
| 1.324e-06 | -13.54 | GSE13485_DAY1_VS_DAY21_YF17D_VACCINE_PBMC_UP | MSigDB lists | GSE13485_DAY1_VS_DAY21_YF17D_VACCINE_PBMC_UP | 165 | 49 | 17377 | 2626 |
TRIM41,CORO7,PNISR,GORASP1,TRIM11,ARID5A,ALKBH5,AGPAT1,ATG2B,IP6K2,RNF103,PIP5K1C,USP5,ZER1,APLP2,ZNF746,AKAP8,GLTP,RPRD1B,PPP6R1,KCNAB2,CARM1,DCTN1,TGFB1,PPP1R9B,PTPN18,DDX24,ATG9A,MAP4K4,LDB1,WBP2,UHRF1BP1,FAM133B,USP36,POLR2A,MAN2A2,ANKRD10,PWWP2B,INF2,ZNF317,HGS,SGSH,PDLIM1,ARNTL,PML,ACTB,CENPT,WDR91,CAPN1 |
| 1.328e-06 | -13.53 | SNRPD3 (small nuclear ribonucleoprotein D3 polypeptide) | protein interactions | 6634 | 125 | 42 | 17029 | 2761 |
SART1,CYLD,SF3B1,SUZ12,CUL1,LMNA,SF3B2,EIF4A3,HUWE1,BANF1,EFTUD2,GEMIN6,STRAP,PABPC1,LUC7L2,HNRNPM,CDC5L,SNRNP200,SNRPB,CUL3,SREK1,DDX20,PRPF3,BRCA1,IL12RB1,MCM2,KIF11,LUC7L,SF3A2,CLNS1A,CAND1,GEMIN5,CHCHD3,HNRNPR,LSM6,RBL1,SNRPG,SNRNP70,CFAP20,SMURF1,CD81,GEMIN7 |
| 1.334e-06 | -13.53 | GSE29617_CTRL_VS_TIV_FLU_VACCINE_PBMC_2008_DN | MSigDB lists | GSE29617_CTRL_VS_TIV_FLU_VACCINE_PBMC_2008_DN | 179 | 52 | 17377 | 2626 |
GLT8D1,SCOC,NDUFB6,SUCLG1,GNPDA1,UQCR10,RPS6KA1,DYNLL1,SDF2L1,PPP3CB,FKBP2,ASXL2,TTF1,COPB2,FAM192A,DECR1,HOMER1,PCNA,PSMD1,NDUFB4,SLC44A1,EFTUD2,MEA1,SLC26A2,OSTC,HDHD2,RNF5,CCT2,TIMM8B,NEK7,PPP1R21,METTL5,RRM2,PITPNB,EAF2,AP4E1,MRPS14,ECH1,PRDX1,PRIM1,XRCC5,SEC61A1,ORMDL2,STT3A,DCK,ACADM,NAA20,FAM208A,HDAC2,ZNF146,TUBB,DDB1 |
| 1.334e-06 | -13.53 | GSE40666_WT_VS_STAT4_KO_CD8_TCELL_DN | MSigDB lists | GSE40666_WT_VS_STAT4_KO_CD8_TCELL_DN | 179 | 52 | 17377 | 2626 |
ZBED3,CASP6,TOR1AIP1,TMX4,CUTA,UCK1,UBLCP1,DECR1,PCNA,UBE2Q2,NT5DC1,SIVA1,AP1M1,CRY2,ACAD8,CITED2,CNPY3,RHBDD2,TPCN1,CTDSP2,S100A6,ABCC5,POLR2I,HMGN5,TIMMDC1,NOA1,DENND4C,RDH10,COG1,IL12RB1,EAF2,TOMM40,ASB13,PRPSAP1,RFC2,ZNF174,EIF3H,BBS12,ARHGAP15,SDHB,PTER,ZNF367,ODF2,CDCA7L,NDUFA11,MPV17,GLG1,IMPDH1,MBOAT1,SPRYD4,GLCCI1,SNX14 |
| 1.334e-06 | -13.53 | GSE16522_ANTI_CD3CD28_STIM_VS_UNSTIM_MEMORY_CD8_TCELL_DN | MSigDB lists | GSE16522_ANTI_CD3CD28_STIM_VS_UNSTIM_MEMORY_CD8_TCELL_DN | 179 | 52 | 17377 | 2626 |
EXOC3,NDUFV2,SYS1,ACTR3,CUTA,CERK,ABCB10,GTF3A,UBE2I,ETS1,PRKACA,CUTC,BIRC2,ARL6IP6,ABHD16A,FBXL6,CTSS,CTNNBL1,NDUFA2,SH3BP1,RINL,SLC35B4,FBXW2,CISD2,RP2,CORO1A,MARCH2,TMEM8A,C12orf75,NDUFA3,GPD1L,WDR41,CSNK1G2,FAM172A,PRIM2,TSPAN31,DCAF8,SELPLG,CUL3,CIRBP,GLO1,GALK2,ASB13,SDHB,FNTA,DCAF11,DTD1,RNF14,TMEM14A,CHID1,PURA,S100PBP |
| 1.334e-06 | -13.53 | GSE36826_NORMAL_VS_STAPH_AUREUS_INF_IL1R_KO_SKIN_DN | MSigDB lists | GSE36826_NORMAL_VS_STAPH_AUREUS_INF_IL1R_KO_SKIN_DN | 179 | 52 | 17377 | 2626 |
KCTD7,CYTIP,GLT8D1,ADAM10,NACA,KIAA0232,CERK,GMCL1,VAV1,ATP6V0B,RNFT1,LRRC8D,ARF5,ANP32A,CLDND1,TALDO1,METTL9,ATP6V0D1,TACC3,SMC4,USP34,ACSL5,AMPD2,TDP1,PPP3CA,EIF3L,POLR2L,GALC,RPL8,ILF3,SSR2,MAP4K3,BICD2,ZFAND5,PICALM,SERP1,RPS9,RHOB,HMGN2,TFEB,ADSS,MAP3K4,AHNAK,OSBPL11,SERF2,TTLL4,SETD3,PITPNA,FAU,ZMIZ1,RTN3,LRP8 |
| 1.334e-06 | -13.53 | GSE46606_UNSTIM_VS_CD40L_IL2_IL5_DAY3_STIMULATED_BCELL_DN | MSigDB lists | GSE46606_UNSTIM_VS_CD40L_IL2_IL5_DAY3_STIMULATED_BCELL_DN | 179 | 52 | 17377 | 2626 |
OTUD5,PKP4,HNRNPAB,GNPNAT1,IVNS1ABP,PPP1R15B,ACTR3,CHD1L,TRMT6,ADO,GNE,EBNA1BP2,NANS,POLR3K,WRNIP1,TET3,MLX,ZNF473,CD3EAP,ZNF200,SRI,MSH2,FEM1B,RPF2,TTC4,SNX25,PPAN,METTL1,RFC3,CDC123,PRKDC,NOL8,LDHA,RABIF,RRM2,CDC6,CBFB,KLF6,TWISTNB,USP36,KIF2A,CDCA4,TIMM13,ETS2,NIP7,SETD3,WDR4,NAA20,NANP,BYSL,RHEBL1,EGLN1 |
| 1.337e-06 | -13.53 | REICHERT_MITOSIS_LIN9_TARGETS | MSigDB lists | REICHERT_MITOSIS_LIN9_TARGETS | 27 | 15 | 17377 | 2626 |
PLK1,ASPM,CEP55,CENPF,MKI67,VCPIP1,KIF23,HMGB2,NUSAP1,CDCA2,KIF2C,CDK11B,CCNB1,CCNF,FBXO5 |
| 1.349e-06 | -13.52 | Ranbp2 (RAN binding protein 2) | protein interactions | 19386 | 77 | 30 | 17029 | 2761 |
TELO2,CHMP2A,NDC1,PDCD6IP,NXT1,NUP188,RAE1,SUMO2,XIAP,NARF,NUSAP1,RANGAP1,NUP155,CDCA2,BICD2,SLC35B2,UBE2I,NUP205,KPNA4,NUP107,NUP62,CHMP4B,NUP153,KPNA2,GLE1,NUP85,SENP1,AAAS,SEH1L,NXT2 |
| 1.354e-06 | -13.51 | RNA transport | KEGG pathways | ko03013 | 166 | 51 | 7161 | 1149 |
NDC1,NUP188,THOC1,RAE1,EIF3D,SUMO2,RBM8A,NUP54,UBE2I,EIF1B,PAIP1,PABPC4,NUP205,SNUPN,EIF2S2,NUP210,EIF4A3,POP7,NUP107,GEMIN6,UPF2,NUP153,GEMIN4,EIF5,PABPC1,NUP85,STRAP,SEH1L,TACC3,RPP25,CYFIP1,NXT1,RNPS1,DDX20,NUP155,RANGAP1,CYFIP2,FXR1,EIF4G2,EIF3G,EIF3H,EIF3A,CLNS1A,GEMIN5,UPF1,NUP62,NUP58,NMD3,AAAS,GEMIN7,NXT2 |
| 1.354e-06 | -13.51 | RNA transport | KEGG pathways | hsa03013 | 166 | 51 | 7161 | 1149 |
NDC1,NUP188,THOC1,RAE1,EIF3D,SUMO2,RBM8A,NUP54,UBE2I,EIF1B,PAIP1,PABPC4,NUP205,SNUPN,EIF2S2,NUP210,EIF4A3,POP7,NUP107,GEMIN6,UPF2,NUP153,GEMIN4,EIF5,PABPC1,NUP85,STRAP,SEH1L,TACC3,RPP25,CYFIP1,NXT1,RNPS1,DDX20,NUP155,RANGAP1,CYFIP2,FXR1,EIF4G2,EIF3G,EIF3H,EIF3A,CLNS1A,GEMIN5,UPF1,NUP62,NUP58,NMD3,AAAS,GEMIN7,NXT2 |
| 1.355e-06 | -13.51 | NADH dehydrogenase complex assembly | biological process | GO:0010257 | 58 | 24 | 17256 | 2622 |
NDUFA5,NDUFV2,NDUFS1,NDUFB6,TIMMDC1,NDUFAF2,TMEM126B,DMAC2,TIMM21,NDUFA7,NDUFB1,TAZ,FOXRED1,NDUFS7,NDUFS4,NDUFAF6,NDUFV1,NDUFA2,NDUFB4,NDUFA11,NDUFS8,NDUFB9,NDUFS5,NDUFA3 |
| 1.355e-06 | -13.51 | mitochondrial respiratory chain complex I assembly | biological process | GO:0032981 | 58 | 24 | 17256 | 2622 |
NDUFA5,NDUFV2,NDUFS1,NDUFB6,TIMMDC1,NDUFAF2,TMEM126B,DMAC2,TIMM21,NDUFA7,NDUFB1,TAZ,FOXRED1,NDUFS7,NDUFS4,NDUFAF6,NDUFV1,NDUFA2,NDUFB4,NDUFA11,NDUFS8,NDUFB9,NDUFS5,NDUFA3 |
| 1.363e-06 | -13.51 | GRAESSMANN_APOPTOSIS_BY_DOXORUBICIN_UP | MSigDB lists | GRAESSMANN_APOPTOSIS_BY_DOXORUBICIN_UP | 1079 | 219 | 17377 | 2626 |
NAT9,PPCS,PDCD6IP,TMEM184B,NDUFB6,UBN1,TRIM11,HEXB,TAP1,GLUD1,ABCB10,CCNL2,IKBIP,CDIPT,BRIX1,UBE2I,BECN1,SLC20A1,RBM4,RNF103,CREM,PA2G4,ATG3,SIVA1,DNM2,AKR1B1,KIF22,TIPARP,FTSJ3,TACC3,FYTTD1,PLK3,CELSR2,LACTB,SLC25A22,MCL1,ESYT1,EAF2,SOX4,MCFD2,PRKRA,ICMT,STK17B,MAK16,ABHD5,ANKRD10,AHNAK,NIP7,PDRG1,SH3GLB2,ARRDC1,ST3GAL2,ATP6V0C,GLCCI1,ZMAT3,CAPN1,SLC25A33,CCDC137,SLC12A7,WSB2,SEPHS2,C9orf78,MAPRE1,LZTR1,PARP12,GORASP1,DNAJB2,CYCS,MAN2B1,DNAJB1,HAUS2,LRRC14,GNS,FAM192A,SLC31A1,RB1,PDXP,CEP104,ZNRF2,EI24,DAPK1,CTR9,ACAD8,RNF135,ZRANB1,SLC12A2,ATP6V0D1,PPA1,TRAFD1,RDH10,EXOSC9,MAP7D1,PLEC,SYVN1,ADRB2,ISG15,RBM38,FAS,RXRB,CCDC86,TTC13,PDLIM1,ERGIC3,EXOC4,ARAP1,SLAIN1,MDH1,SMPD4,WIPI2,PPP6R3,EHD4,RNF14,PDLIM5,TRIM41,PPP1R37,ZNF296,GGNBP2,MPHOSPH8,FAM207A,XAB2,OLA1,ZFYVE21,RRAGC,INO80E,CLCC1,SLC25A44,ATP6V1B2,TWF2,GLRX3,BCAP31,MOAP1,CRKL,CYHR1,ATP6V0B,MDM2,SP100,SIAH1,TNPO2,CORO1A,MAVS,CLTB,RBM15,NAA35,GCC1,TMBIM1,SAP30,PPIF,PSRC1,BTG2,DRAP1,CPOX,CIRBP,DNAJC9,LRRC8A,NFATC2,DNAJA1,HERPUD2,PSMB9,GFER,TMEM41A,SURF4,SEC61A1,MAFK,NDUFA11,ARNTL,STAT1,SCARB1,TRIM32,NCOA1,SPRYD4,PPP5C,OTUD5,TOR3A,CDK2AP2,LANCL1,MXD4,GGA2,SLC12A9,SPR,IFT27,FAM8A1,DNAJB9,SAC3D1,SRXN1,PDCD10,CRAT,PTPN11,GTSE1,CLDND1,CITED2,TPCN1,FRMD8,MSH6,MYO5A,PDPK1,AMPD2,STAU1,RNASEH2C,SNX2,POLK,TOP3A,EMP3,DDX39A,HAGH,POLR2A,HSPA1B,ATP6V1D,FAM110A,PARG,PGRMC1,PML,E2F1,USP20,AEN,RGL1,CENPT,ATP6V1C1,HRAS,IFI16 |
| 1.381e-06 | -13.49 | RAD23B (RAD23 homolog B, nucleotide excision repair protein) | protein interactions | 5887 | 121 | 41 | 17029 | 2761 |
ATXN3,EWSR1,RBM8A,DNAAF5,NANS,UBQLN2,BLM,SPR,NPLOC4,USP5,RAD23A,PSMD2,PSMD1,EIF4A3,UCHL5,AHSA1,TACC3,UBQLN4,DEAF1,DRAP1,PSMB7,ADSL,UBE4B,BRCA1,PKM,MPG,ZFAND5,COMMD4,PSMC4,RPA1,NUCB1,CORO1C,STAT6,DBI,PRDX5,IGBP1,PDLIM5,ECPAS,NGLY1,PSMC1,NMD3 |
| 1.381e-06 | -13.49 | MCM4 (minichromosome maintenance complex component 4) | protein interactions | 4173 | 121 | 41 | 17029 | 2761 |
USP7,MCM10,TRIP10,IVNS1ABP,SF3B1,CDT1,ANK3,DCTN2,DBF4,ATG2B,ORC1,NCKAP1,SF3B2,RPA2,PCNA,SMC3,HUWE1,MCM5,CRY2,NUP153,ORC3,MCMBP,CDC5L,PLK1,MAPRE2,POLK,E2F3,BRCA1,MCM2,SOX4,CDK11A,ASF1B,RPA1,SUPT16H,KPNA4,TONSL,SAFB,H2AFX,FKBP5,CDK2,SSRP1 |
| 1.393e-06 | -13.48 | PRCC (papillary renal cell carcinoma (translocation-associated)) | protein interactions | 5546 | 48 | 22 | 17029 | 2761 |
SARNP,EWSR1,CRNKL1,CSNK2A1,GORASP2,SEPT7,SCYL2,SF3A2,MAD2L2,SH3GLB1,IWS1,CDK5,SUB1,PPIL2,NABP2,SEPT11,YWHAZ,LRP8,CARM1,FAF1,CDC5L,PRPF19 |
| 1.403e-06 | -13.48 | ATP6V1F (ATPase H+ transporting V1 subunit F) | protein interactions | 9296 | 55 | 24 | 17029 | 2761 |
UNK,TXN,TRIM11,UFC1,VDAC2,TMEM216,UBE2V1,UBE4B,ATP6V1B2,PICALM,SRXN1,VASP,ATP6V1D,CORO1C,MPV17,ATP6V0A2,ZRANB2,TTLL12,IGBP1,UBE2C,ATP6V0D1,DDB1,SSSCA1,ABCC1 |
| 1.403e-06 | -13.48 | GNF2_RAN | MSigDB lists | GNF2_RAN | 82 | 30 | 17377 | 2626 |
CCT2,IMMT,RFC3,H2AFZ,MRPL42,PRKDC,OLA1,RRM1,SLBP,ADSL,SNRPD3,ODC1,CCT8,TARS,SNRPA,XRCC5,HNRNPA2B1,EPRS,PA2G4,MTHFD2,EIF2S2,IARS,ATIC,BANF1,LRPPRC,PTGES3,SNRPG,MRPL3,MSH6,SSRP1 |
| 1.404e-06 | -13.48 | RPL24 (ribosomal protein L24) | protein interactions | 6152 | 155 | 49 | 17029 | 2761 |
RPS15,RPS2,MPHOSPH8,RPLP2,SRSF6,TCF3,RPL15,CUL1,CHCHD2,RPL11,RPL23A,GART,IARS,EIF4A3,RPL17,RPL19,STRAP,STAU1,RPL35,OXR1,RPS10,RPL6,CUL3,ILF3,RPL8,RPL38,RPS24,LSM8,BRCA1,MCM2,RPL27A,RPS9,RPSA,ISG15,CAND1,RPL36,XRCC5,NAP1L1,TIMM13,SYNCRIP,RPL32,RPS27A,RPS14,RPLP1,COPS6,SMURF1,CD81,RPS26,FAF1 |
| 1.405e-06 | -13.48 | UDAYAKUMAR_MED1_TARGETS_UP | MSigDB lists | UDAYAKUMAR_MED1_TARGETS_UP | 129 | 41 | 17377 | 2626 |
RMND5A,TMED7,MRPL42,NF1,SRGN,NIT2,PAWR,SLC29A1,SDF2L1,PPP3CB,LRRC14,SUB1,GRSF1,FEM1B,CREB1,OGG1,PHF10,ZMYND11,ACSL3,MRPL12,CDC6,EDF1,SF3A2,EML4,DHX15,EIF3A,CHAF1A,RDH11,PTPRF,SLC19A1,RBM47,OSBPL8,PTER,NAGLU,PITX1,SLC16A1,CNOT6,ANP32E,CHPT1,BRD9,LRP8 |
| 1.405e-06 | -13.48 | CS (citrate synthase) | protein interactions | 1431 | 38 | 19 | 17029 | 2761 |
ZNF207,DYNLL1,RAE1,MDH2,IDH3A,SND1,MCM2,SDHA,PDHX,SDHB,PA2G4,HUWE1,TAB2,ACLY,CTPS1,ANXA5,GPI,USP11,ATF2 |
| 1.411e-06 | -13.47 | GSE41867_LCMV_ARMSTRONG_VS_CLONE13_DAY6_EFFECTOR_CD8_TCELL_UP | MSigDB lists | GSE41867_LCMV_ARMSTRONG_VS_CLONE13_DAY6_EFFECTOR_CD8_TCELL_UP | 184 | 53 | 17377 | 2626 |
H2AFZ,TXN,MRPL42,GNPNAT1,AGRN,PHRF1,UQCR10,KIAA0232,PTTG1,TMEM97,SLC29A1,ORC1,PCBP1,TFRC,PRPF18,SEC11A,LYAR,ZNF428,SUB1,NUP210,EIF4A3,HADHB,ORAI1,YIF1B,YBX1,GLE1,MRPL40,MRPL21,HTRA2,EIF5A,TIMM8B,TRAFD1,DDX24,DHX29,VDAC2,BOLA1,ESYT1,TRIM28,ABCF1,FADD,STOML2,SLC19A1,AHNAK,TMED10,PSMD8,ITGB1,PML,ACAT1,PREPL,PDCD11,PDSS2,HRAS,GCSH |
| 1.411e-06 | -13.47 | GSE22919_RESTING_VS_IL2_IL12_IL15_STIM_NK_CELL_DN | MSigDB lists | GSE22919_RESTING_VS_IL2_IL12_IL15_STIM_NK_CELL_DN | 184 | 53 | 17377 | 2626 |
CYLD,CKLF,MUT,CDK2AP2,TCF3,ARID5A,MCCC1,GTF3A,TMED3,CLCC1,MIEN1,LCLAT1,GNB2,NAPG,TRMU,PHF14,CDKN1B,CABLES2,CREB1,GPD1L,N4BP2,VPS13B,CYTH1,PTPN18,SEPT9,PPT1,TSPYL4,DENND1B,OXR1,KIAA0930,KCTD20,COG1,MAP4K3,EAF2,RFC2,COMMD4,ECH1,BSDC1,TMEM184C,ANKZF1,MTMR3,NAP1L1,HSPB11,WDR11,L3MBTL3,CAMKMT,APPL2,ZFP90,GPI,AKNA,TMEM14A,PDCD4,CAPN1 |
| 1.411e-06 | -13.47 | GSE17721_0.5H_VS_8H_POLYIC_BMDC_UP | MSigDB lists | GSE17721_0.5H_VS_8H_POLYIC_BMDC_UP | 184 | 53 | 17377 | 2626 |
NCOR2,TRIM41,GNPNAT1,THOC1,FOXM1,MRPS2,MRPS15,SNX15,CUTA,OLA1,SEC16A,PMVK,PARK7,PNO1,EBP,STRBP,IL6ST,GEMIN6,MRPL54,BCAP29,SLC35A1,MED22,CCT2,TK1,HARS,AACS,IDH3A,MAP4K4,DNAJC9,HTATIP2,GALK2,CDC23,MCM2,VDAC1,TXNL4A,BTBD1,CLNS1A,NUCB1,ORMDL2,ACOX1,LIMK1,PITX1,MPV17,FTSJ1,RPLP1,PRMT7,USP20,ACAT1,MDH1,PDXK,NAA60,MRPL3,IPO4 |
| 1.411e-06 | -13.47 | GSE37301_COMMON_LYMPHOID_PROGENITOR_VS_CD4_TCELL_DN | MSigDB lists | GSE37301_COMMON_LYMPHOID_PROGENITOR_VS_CD4_TCELL_DN | 184 | 53 | 17377 | 2626 |
EXOC3,GGNBP2,CDT1,YTHDC2,RRM1,MYH9,HMGN3,CDK13,NOTCH2,MXD4,PTPN2,SEC11A,NFATC3,INPP5A,NVL,ARPC5,KIF14,TRMU,ZDHHC13,DNM2,HADHB,CYB5R1,RNASEH2A,MRPL40,TECR,PIKFYVE,GNAI2,F2R,MTX2,PCBP2,TMX1,SOCS5,WDR41,CSNK1G2,GALC,PPT1,DENND1B,DENND4C,FXR1,CHAF1A,ZMYM3,CHCHD3,ANKZF1,SMAD2,JAK1,BIRC5,ELMO1,STAT1,GALNT10,COPS6,TFDP2,RTN3,MYL12B |
| 1.411e-06 | -13.47 | GSE32986_GMCSF_AND_CURDLAN_LOWDOSE_VS_GMCSF_AND_CURDLAN_HIGHDOSE_STIM_DC_UP | MSigDB lists | GSE32986_GMCSF_AND_CURDLAN_LOWDOSE_VS_GMCSF_AND_CURDLAN_HIGHDOSE_STIM_DC_UP | 184 | 53 | 17377 | 2626 |
UBL3,NAT9,NSMCE4A,UGP2,REPS2,ZCCHC8,RPS6KA1,RAF1,WDR13,GADD45G,YTHDC2,TIA1,ASXL2,TMEM165,COMMD8,WRB,HMG20A,PDXDC1,CCDC28A,NDUFS7,TMCC3,FERMT3,ZBTB45,KIF13B,PPIL2,ZNF746,PRC1,SLC38A10,MAVS,TALDO1,MGAT5,DEAF1,PTPN18,TRAFD1,PGGT1B,DCAF8,EHMT1,SLC16A7,SLBP,PFKFB3,PLEKHM3,AMDHD2,PPWD1,KIF11,PRIM1,RBL1,DUSP3,LUC7L3,STK38,UHRF2,PREPL,CDK2,RTN3 |
| 1.411e-06 | -13.47 | GSE44649_NAIVE_VS_ACTIVATED_CD8_TCELL_MIR155_KO_UP | MSigDB lists | GSE44649_NAIVE_VS_ACTIVATED_CD8_TCELL_MIR155_KO_UP | 184 | 53 | 17377 | 2626 |
MAPRE1,NOP2,PHF23,SNN,SLC20A1,PCBP1,CHD1,DNAJB9,PAIP2,CHKA,RBM17,PTPN2,GNS,USF1,APLP2,SLC31A1,PCNA,EIF2S2,TIMM23,UTP18,FAM76B,OSTC,EIF5,PPA1,CGGBP1,PPAN,IFRD1,HMGN5,SLC16A7,CRNKL1,ILF3,SLBP,TOR1AIP2,KRAS,FXR1,GAR1,EIF3A,NUCB1,KPNA1,CDCA4,ETS2,NIP7,FAM3C,CAB39,MRFAP1L1,SNRPG,PDXK,RRS1,PGAM1,VPS29,BYSL,FUBP1,S100PBP |
| 1.423e-06 | -13.46 | DUSP13 (dual specificity phosphatase 13) | protein interactions | 51207 | 81 | 31 | 17029 | 2761 |
COPS8,OTUD5,EIF5A,EXOSC6,TXN,CPOX,DCTN2,PITHD1,GINS4,LMNA,RPL36,SDHB,MTHFD2,DUSP3,PRDX3,DUT,PRDX5,UBA5,NAGLU,PPA2,ACLY,NUP107,PTPN11,NFU1,PDIA6,PGAM1,WDR45B,SMURF1,PPA1,NCOA2,DCTN1 |
| 1.428e-06 | -13.46 | SENP3 (SUMO specific peptidase 3) | protein interactions | 26168 | 117 | 40 | 17029 | 2761 |
IMMT,PDCD6IP,XAB2,MAGED1,SUMO2,MOGS,RRM1,CDCA8,CUL1,WDR5,COPG2,TFRC,CSDE1,PSMD2,MDM2,MCM5,ZNF746,ALDH18A1,CDC5L,TELO2,NSUN2,WDR18,TEX10,CUL3,ILF3,MEF2D,MEN1,USP21,TRIM28,MATR3,TARS,DHX15,DDX17,XRCC5,UBTF,QARS,IFI16,CDKN2A,PFKP,SSRP1 |
| 1.428e-06 | -13.46 | LYPD3 (LY6/PLAUR domain containing 3) | protein interactions | 27076 | 117 | 40 | 17029 | 2761 |
NDC1,SLC41A1,DNAAF5,ARFIP2,UBE2Q1,SLC35B2,XPO7,QSOX2,BZW2,EBP,ASPHD2,THADA,SLC44A1,PHTF1,PDS5B,TNPO2,TNPO3,CLDND1,CLCN3,RB1CC1,BTAF1,HSDL1,TBRG4,USP22,DCUN1D5,MTX1,TOMM40,SYMPK,BRMS1,PLAA,PALB2,LMBR1,STK11,GALNT10,CHEK2,NR2F2,ECPAS,C2CD5,SMAD4,AAAS |
| 1.428e-06 | -13.46 | HHV8GK18_gp81 (ORF73) | protein interactions | 4961527 | 117 | 40 | 17029 | 2761 |
USP7,H2AFZ,UBN1,TWNK,MECP2,SUMO2,SND1,REEP5,PIP4K2A,CREM,RPA2,NRF1,XPA,ATF2,NCOA2,PCBP2,CARM1,RLIM,SRSF11,TDP1,RBX1,PRKDC,VHL,PPIE,PIP4K2C,PRMT2,KDM3A,H2AFV,TRIM28,EPB41,RPA1,DPYSL3,RAD51C,PRMT7,ZRANB2,RBPJ,PPP5C,SNRNP70,TERF1,RAD51D |
| 1.428e-06 | -13.46 | ELAVL2 (ELAV like RNA binding protein 2) | protein interactions | 1993 | 117 | 40 | 17029 | 2761 |
CDC40,HNRNPAB,XAB2,GSPT2,HNRNPUL2,SAFB2,SRRT,PAIP1,PABPC4,GTPBP3,STRBP,ZNF326,TRA2B,TARDBP,RBM3,AQR,ZC3H3,PABPC1,SRSF10,CDC5L,YTHDC1,CDKN2AIP,PPIE,SUGP2,RNPS1,CUL3,CRNKL1,PRKRA,MATR3,ZFR,SRSF1,CAND1,UPF1,SYNCRIP,CLK3,HNRNPR,RBMX,SAFB,H2AFX,CDK2 |
| 1.434e-06 | -13.45 | MORF_ATOX1 | MSigDB lists | MORF_ATOX1 | 74 | 28 | 17377 | 2626 |
SEPHS2,KARS,DPM1,SEC61G,RAC1,DCTN2,GMFB,ENSA,TMEM147,RAB1A,BCAP31,PSMC4,PDCD6,PSMD8,ARF5,BANF1,RAD23B,BUD31,PGRMC1,COX5A,SNRPG,CLN3,PLOD3,PSMC1,AP2S1,MYL12B,TMED2,SLC25A1 |
| 1.438e-06 | -13.45 | ARM-type_fold | interpro domains | IPR016024 | 340 | 84 | 18492 | 2768 |
NOP9,NUP188,TSC2,NF1,ARID2,SF3B1,UBQLN2,AP1B1,PAIP1,ZER1,PSMD1,THADA,INTS1,NOC2L,PDS5B,TNPO2,AP2B1,EIF5,SCYL3,USP34,USO1,LRBA,ARMH3,AP4E1,EIF3K,TAF2,PPP2R5A,CAB39,KPNA2,LTA4H,PDCD4,MIF4GD,PKP4,TRIP12,SCYL1,DNAAF5,XPO7,DOCK11,NCAPG,SCYL2,BZW2,COPG2,HEATR5B,PSMD2,CEP104,CTNNBL1,HUWE1,INTS7,PPP4R1,TNPO3,LTN1,KIFAP3,UPF2,PPP6R1,TELO2,IFRD1,FOCAD,ASPM,BTAF1,PRKDC,TEX10,ARID1A,EIF4G2,ARMC8,API5,SYMPK,CIP2A,NCDN,CAND1,CNOT9,UTP20,TSC1,INF2,KPNA1,KPNA4,HSPBP1,PLAA,ELMO1,SIL1,PPP6R2,PPP6R3,ECPAS,TAF6,IPO4 |
| 1.460e-06 | -13.44 | pancreas-carcinoid-endocrine_tumour-non_functioning | COSMIC cancer mutations | pancreas-carcinoid-endocrine_tumour-non_functioning | 11 | 9 | 17385 | 2587 |
CDKN2C,RB1,NRAS,PTEN,VHL,KRAS,MEN1,SMAD4,CDKN2A |
| 1.460e-06 | -13.44 | gastrinoma | COSMIC cancer mutations | gastrinoma | 11 | 9 | 17385 | 2587 |
GNAS,CDKN2C,NRAS,PTEN,KRAS,MEN1,SMAD4,HRAS,CDKN2A |
| 1.480e-06 | -13.42 | UBE2S (ubiquitin conjugating enzyme E2 S) | protein interactions | 27338 | 85 | 32 | 17029 | 2761 |
UBE2D3,USP7,KARS,CYLD,ATXN3,VHL,TPX2,USP10,ANAPC2,NFATC2,PMF1,CDC23,USP21,APP,BIRC2,USP5,XRCC5,FBXO5,CDC16,PPP2R5A,SYNCRIP,CDC27,HNRNPR,ANAPC7,TTC4,ZRANB1,UBE2C,HNRNPDL,ZNF598,ANAPC4,PDCD4,CDC5L |
| 1.484e-06 | -13.42 | ISG15 (ISG15 ubiquitin-like modifier) | protein interactions | 9636 | 186 | 56 | 17029 | 2761 |
DDX58,UBE2D3,UGP2,NACA,TKT,YTHDF3,MYH9,CSNK2A1,DNAJB1,ATP5F1B,CHD1,LMNA,HNRNPA2B1,ATIC,ANXA5,UTP4,SENP1,CFL1,RBM15B,YTHDC1,CCT2,SNRNP200,LAP3,WDR1,ABCF2,LDHA,EZR,OGDH,PLEC,PKM,RPL27A,USP21,SF3A2,TARS,PRDX1,RDH11,DDX17,XRCC5,TAF2,HSPA4,AHNAK,RPS27A,STK38,MAP4,STAT1,ACLY,ATXN2L,ATP5F1A,GPI,PLOD3,RBBP4,SMAD4,CBX4,ZC3HAV1,AAAS,DDX42 |
| 1.484e-06 | -13.42 | GSE21360_PRIMARY_VS_TERTIARY_MEMORY_CD8_TCELL_UP | MSigDB lists | GSE21360_PRIMARY_VS_TERTIARY_MEMORY_CD8_TCELL_UP | 189 | 54 | 17377 | 2626 |
TCF12,RHOG,TBC1D12,NCOR2,NQO1,DHPS,PHB2,KLHL21,URB2,UCK2,LAGE3,RPL15,LETMD1,NKRF,ARF1,TWF2,MAPK14,FOXO3,PHC2,FARSA,NFATC3,PCNA,SH3BP1,KIF13B,ARHGEF2,TCEA1,LYPLA2,ABCC1,NUDC,CLPTM1,ACP2,KAT7,ARHGDIB,USP22,PLEC,CBFA2T2,ZFAND5,ODC1,RAB5B,KDM3A,RDH11,MYO1F,GNA12,ALDH3B1,SGSH,POLR2J,CSK,TATDN2,ARAP1,OGT,BTF3,USF2,YWHAH,PURA |
| 1.501e-06 | -13.41 | vacuole | cellular component | GO:0005773 | 777 | 163 | 18223 | 2701 |
ADA2,RAB14,TSC2,AGRN,ABCC10,HEXB,NHLRC3,GYG1,UBQLN2,MAP1LC3B,BECN1,CMTM6,GLMP,PCYOX1L,NAPG,PA2G4,PSMD1,AP1M1,AKR1B1,AP2B1,MARCH2,DRAM2,SEH1L,WDR41,LARS,MIOS,ATG9A,ARHGAP45,LRBA,SLC17A5,RHEB,PLEKHF2,OPTN,AHNAK,TBC1D17,WDR11,NAGLU,ATP6V0C,VPS4A,CLN3,CAPN1,ANXA11,STARD3NL,TBC1D12,DNAJC5,CCZ1,CDIP1,RAB23,LAMTOR3,SDC2,ASAH1,B4GALT1,MAN2B1,PSEN1,TMEM165,WDR48,TMEM179B,GNS,VMP1,ZNRF2,ATP6V0A2,TMEM8A,LPCAT1,ATP6V0D1,ABCC1,FTL,CPQ,CREG1,PIP4K2C,GBA,ADRB2,CCT8,RMC1,PI4K2A,CAT,SCARB2,NSF,SNAP23,LAMTOR4,ACLY,CTSA,WIPI2,HEXA,SNX14,ANKRD27,TRIP10,ANK3,TMEM97,VTI1A,RRAGC,ATP6V1B2,AP1B1,LYN,GNB2,CPNE3,USP5,ATP6V0B,RALB,TBC1D14,CLCN6,BRI3,RPN2,TMEM9,TMBIM1,GM2A,ATP6V1G1,CPNE1,UBQLN4,CCT2,PPT1,GOPC,RAB7A,ATP6V0A1,CHMP2B,TOLLIP,PON2,DSN1,SURF4,DDOST,RAB24,WDR59,AP1S1,TICAM1,SCARB1,MAPK1,AP2S1,CHID1,DYNC1LI2,TUBB,ANXA6,MANBA,SRGN,FLOT1,PIP4K2A,SPPL2A,CAPN2,CTSS,TPCN1,MYO5A,MFSD12,ACP2,TNFAIP3,GALC,SNX2,RFFL,HEBP2,KCNQ1,WDR81,SPPL2B,NEU1,SH3GLB1,CTSL,SGSH,ATP6V1D,HGS,MAGT1,CCZ1B,SNAP29,CTBS,IMPDH1,PSAP,ATP6V1C1,SNAPIN |
| 1.505e-06 | -13.41 | SKP1 (S-phase kinase associated protein 1) | protein interactions | 6500 | 204 | 60 | 17029 | 2761 |
SUZ12,CDCA3,CUL1,KLC1,FKBP2,ATP6V1B2,PCBP1,PIP4K2A,FBXO22,FBXO5,EEF2K,FBXO3,TFAP4,FBXL6,CCNA2,KDM2A,PTEN,ETV6,FBXO7,TTC9C,NABP2,FBXW2,CDKN1B,FOXN2,CRY2,FBXL7,CDC25B,AHCYL1,FBXL19,CDC37,RYBP,RBX1,BTG2,PIP4K2C,CUL3,FBXO9,SLBP,MCL1,BRCA1,ARID1A,MCFD2,MCM2,PCGF1,CCNF,BORA,CAND1,FBXO21,FBXO41,FBXO28,CCDC6,CORO1C,PML,UHRF2,COPS6,FBXL3,SNRNP70,CDK2,TERF1,FAF1,ZC3HC1 |
| 1.505e-06 | -13.41 | ATP6AP2 (ATPase H+ transporting accessory protein 2) | protein interactions | 10159 | 109 | 38 | 17029 | 2761 |
RHOG,RAB14,CHMP2A,UNK,GOLIM4,TMUB1,URB2,FLOT1,FKBP2,ATP6V1B2,RAB11A,KTN1,TFRC,WWP2,CD59,MECR,ATP6V0A2,ATP6V0D1,ATP6V1G1,RHOA,RAB7A,WDR1,TMEM216,ATP6V0A1,RANGAP1,CHMP2B,VKORC1,GOSR1,EVC2,SDHB,PON2,ATP6V1D,USP20,ATP6V0C,ATP6V1C1,ZBTB11,NUMB,ESYT2 |
| 1.543e-06 | -13.38 | SNRPA (small nuclear ribonucleoprotein polypeptide A) | protein interactions | 6626 | 93 | 34 | 17029 | 2761 |
EWSR1,SUZ12,SF3B1,CUL1,PCBP1,PAPOLA,GTF2F1,ATIC,RBM3,AHCYL1,PABPC1,PCBP2,CDC5L,PRPF19,SRPK2,SRSF11,RBM42,TRIR,PRKDC,RNPS1,CUL3,CIRBP,MATR3,SF3A2,SNRPA,CAND1,TIMM13,RBMX,HNRNPH3,SNRPG,SNRNP70,CDK2,SMURF1,CDKN2A |
| 1.548e-06 | -13.38 | NUP107 (nucleoporin 107) | protein interactions | 57122 | 101 | 36 | 17029 | 2761 |
NDC1,NUP188,SUZ12,RAE1,RAF1,CENPF,NUP54,UBE2I,NUP205,WRNIP1,AHCTF1,NUP210,ZNF746,NUP153,GLE1,NUP85,SENP1,SEH1L,CDC5L,NXT1,PRKDC,WDR1,CUL3,NUP155,RANGAP1,KRAS,BRCA1,H2AFV,KPNA4,SEC61A1,ACLY,NUP62,SMPD4,NUP58,IFI16,AAAS |
| 1.548e-06 | -13.38 | ATP6V1B2 (ATPase H+ transporting V1 subunit B2) | protein interactions | 526 | 101 | 36 | 17029 | 2761 |
INTS2,UNK,EYA1,UFC1,TRMT6,ATP5F1B,WDR5,SRXN1,CSDE1,IARS,PIN1,SEC24C,MSH2,ATP6V0A2,YIF1B,AHCYL1,TFG,ATP6V0D1,RPRD1B,PABPC1,GCC1,MSH6,USP34,RAB7A,UBE2V1,STX16,CCT8,POLR2A,CNOT9,EPRS,ATP6V1D,CHMP4B,ATP5F1A,UBE2C,SSSCA1,SSRP1 |
| 1.548e-06 | -13.38 | WD40 | smart domains | SM00320 | 265 | 67 | 9493 | 1367 |
CORO7,COPA,TRAF7,WDR13,POC1A,WDTC1,GNB2,WDR44,UTP18,FBXW2,TAF5L,CORO1A,UTP4,STRAP,SEH1L,CSTF1,WDR41,PRPF19,MLST8,MIOS,LRBA,SMU1,WDHD1,WDR82,EML4,GEMIN5,BRWD1,WDR11,SCAP,TBL3,CORO1C,WDR59,WDR4,WDR7,PRPF4,DMWD,PPP2R2D,DCAF5,AAAS,WSB2,CDC40,RAE1,STRN4,WDR5,COPB2,WDR48,RFWD3,DTL,PREB,DCAF6,DCAF8,WDR1,WDR18,UTP15,WDR81,PPWD1,ARPC1A,SEC31A,PLAA,DCAF11,WIPI2,WDR76,WDR62,WDR91,RBBP4,WDR45B,BRWD3 |
| 1.549e-06 | -13.38 | EPPERT_PROGENITOR | MSigDB lists | EPPERT_PROGENITOR | 125 | 40 | 17377 | 2626 |
ANKRD27,TMEM97,RRM1,C5orf30,TM9SF3,CSNK2A1,RACGAP1,STAM,TFRC,FANCI,DTL,PSMD1,CTNNBL1,METTL14,DUT,FBXO7,KIFAP3,KNTC1,MINPP1,AHCYL1,FAM171A1,LDHB,RFC3,NET1,IDH3A,PRKDC,BMS1,EIF2AK1,ODC1,ARMC8,PHF6,SUPT16H,PEX5,IDE,MTHFD2,PDLIM1,HNRNPR,LRPPRC,CHEK2,CCNB2 |
| 1.554e-06 | -13.37 | organelle assembly | biological process | GO:0070925 | 726 | 157 | 17256 | 2622 |
RAB14,FGFR1OP,PDCD6IP,NPHP4,NOP2,XIAP,CNTROB,AGFG1,BRIX1,MAP1LC3B,BECN1,BIRC2,MIS12,EDC3,RPL23A,KIFC1,RAB8A,NEK6,RAB35,DNAAF2,ATG3,RPF2,PLK1,SEPT9,ATG9A,FOPNL,TMEM216,EZR,AURKB,ANLN,SEPT1,HSPB11,NIP7,RPS14,E2F4,ITGB1,ATXN2L,CHEK2,PTPDC1,VPS4A,RRS1,SASS6,RPS15,MAPRE1,CENPF,RAB23,DNAAF5,KIF23,MEF2A,HAUS4,RACGAP1,PSEN1,VPS25,HAUS2,ATG4A,CFLAR,TMEM250,CCP110,KIFAP3,ATP6V0D1,NSUN4,DDX28,RB1CC1,WDR1,RPL6,RPS10,MYBL2,SEPT8,EIF2A,SEPT7,PATL1,HAUS8,PCM1,GOLGA2,ODF2,TBPL1,NUP62,WIPI2,NDE1,CFAP20,CDK2,BCCIP,ZNF207,CHMP2A,FAM92A,POC1A,DYNLL1,ACTR3,TPX2,C5orf30,EFL1,PRKACA,STAM,RPL11,CLUAP1,UBXN2A,ABRAXAS2,NSFL1C,SEPT11,CEP63,CORO1A,DCTN1,ULK3,BIRC3,RAB7A,CIRBP,TUBGCP5,RPL38,GORAB,CHMP2B,RAB1A,RPSA,KIF2A,CHMP4A,UBXN2B,GOLGA8A,CHMP4B,SMURF1,TUBB,ATMIN,CSNK1D,KIF3B,MZT1,DCTN2,ATG2B,WDR5,IFT27,RAB11A,TUBGCP2,FBXO5,STARD9,PTEN,CENPJ,ATG13,MRPL11,IFT46,PACS2,PPAN,RHOA,TCTEX1D2,NEK7,ASPM,WDR18,RAB3IP,KIF11,MFN2,NEK1,ATP6V1D,HGS,BIRC5,SNAP29,CCDC69,SSNA1,CENPT,WDR62,WDR45B,CHMP7 |
| 1.554e-06 | -13.37 | GSE9006_TYPE_1_DIABETES_AT_DX_VS_4MONTH_POST_DX_PBMC_UP | MSigDB lists | GSE9006_TYPE_1_DIABETES_AT_DX_VS_4MONTH_POST_DX_PBMC_UP | 194 | 55 | 17377 | 2626 |
SLC30A9,NADSYN1,SART1,IER2,MAPRE1,IVNS1ABP,TSC22D3,CDT1,GLUD1,SAFB2,MFSD10,PABPC4,RGS1,CREM,RPN1,RAB8A,NDUFV1,VASP,NOC2L,COPS7B,RBM3,TP53BP2,ATP6V0D1,CARS2,CDC37,PLK3,PPIF,TNFAIP3,KIAA0930,WDR18,MRPL12,CIRBP,ATP6V0A1,PFKFB3,MCL1,AMDHD2,PAF1,TPD52L2,EIF4ENIF1,UAP1,ELMO1,SAFB,ODF2,MAPK6,NFIL3,GLG1,PRMT7,SIL1,HMGB2,YWHAZ,GPI,WIPI2,EHD4,RTN3,ADNP2 |
| 1.564e-06 | -13.37 | nucleoside triphosphate metabolic process | biological process | GO:0009141 | 246 | 66 | 17256 | 2622 |
COX15,NDUFA5,SUCLG1,NDUFB6,UQCR10,UCK2,OLA1,UCK1,EFL1,ADPGK,ATP6V1B2,ATP5PF,SDHA,DUT,NDUFB9,ATP6V0A1,OGDH,NDUFA7,NDUFB1,TAZ,STOML2,NDUFA11,COX5A,DHTKD1,UQCRH,PFKP,NDUFV2,COX5B,GALK1,NDUFS1,MECP2,RAB23,NDUFA4,CYCS,COX4I1,ATP5F1B,NDUFS7,NDUFS4,NDUFV1,NDUFA2,NDUFB4,MSH2,CTPS1,ATP6V0A2,NDUFS8,CYC1,NDUFA3,TGFB1,RHOA,GUK1,LDHA,ATP5MF,PKM,HSPA1B,MBIP,ATP5MC3,PARG,COX7A2L,TBPL1,COX8A,IMPDH1,ATP5F1A,GPI,NDUFS5,PGAM1,NIPSNAP2 |
| 1.565e-06 | -13.37 | V$E2F_Q4_01 | MSigDB lists | V$E2F_Q4_01 | 218 | 60 | 17377 | 2626 |
POLA2,H2AFZ,ZCCHC8,RAB11B,SMC6,CTCF,ORC1,STMN1,ASXL2,FBXO5,RNF121,PCNA,SMC3,INTS7,DPYSL2,PPP1R8,PDS5B,TNPO2,KNTC1,PCYT2,CITED2,ANKHD1,DNMT1,ARID4A,LUC7L2,EIF5A,PPP1R9B,NASP,ERF,PRKDC,ABCF2,E2F3,SREK1,FBXO9,SLBP,CDC6,SMC2,PKMYT1,NUTF2,MCM2,KDM3A,MAT2A,SRSF1,HMGN2,PRIM1,DDX17,EIF3K,ATAD2,GPS2,DCK,ZNF367,NDUFA11,E2F1,ATE1,ANP32E,RBPJ,WDR62,RBBP4,SASS6,GEN1 |
| 1.569e-06 | -13.36 | CSNK2A2 (casein kinase 2 alpha 2) | protein interactions | 1459 | 264 | 73 | 17029 | 2761 |
TRIM41,REPS2,NOP2,PHRF1,CSNK2A1,CCNL2,MAPK14,CREM,PRNP,MDM2,SYNM,PIN1,HADHB,TTC3,CLTB,ATF2,CDC37,PRPF19,RYBP,CDC5L,PCGF6,RNPS1,SLBP,LUC7L,MAK16,FKBP3,EIF3H,PAF1,WAS,BRD2,HPS5,HAGHL,EFCAB14,BTF3,ARRB2,SMURF1,NKAPD1,COIL,CCDC59,ABCA1,CBX4,HDAC2,CTDP1,NIFK,HSPH1,PPP1R2,SDC2,THRAP3,HDGFL2,CDK11B,WDR5,PIP4K2A,WDR48,FBRS,RPA2,ERH,MLX,PTEN,HUWE1,PPP1R8,NAP1L4,TTLL12,LUC7L2,TERF2,GTPBP4,PIP4K2C,BCLAF1,CDK11A,RPA1,TCOF1,NDE1,TERF1,IFI16 |
| 1.576e-06 | -13.36 | DBN1 (drebrin 1) | protein interactions | 1627 | 227 | 65 | 17029 | 2761 |
USP7,COX15,LUZP1,SUZ12,ACTR3,MYH9,SEC16A,MAP1LC3B,GNB2,PARK7,DST,SNUPN,CDC42,IARS,RABGAP1L,AP2B1,CLTB,CFL1,BAK1,PPP1R18,ERBIN,RAB1A,ANLN,TIMM13,TAB2,CORO1C,MYO18A,CHMP4B,ACTB,ARRB2,ZNF598,POT1,NUMB,UBE2D3,MAPRE1,PPP1R12A,DCTN2,CDK2AP2,FLOT1,XPR1,CD59,HOMER1,GART,UBE2Q2,ARPC5,PTEN,MCM5,GTSE1,NAP1L4,MYO5A,CAMK2G,SPTAN1,PPP1R9B,WDR1,ERLIN1,CAPZA2,ARPC1A,PICALM,GNAS,INF2,NAP1L1,MAPK6,CDK2,TERF1,NUDT3 |
| 1.577e-06 | -13.36 | Electron Transport Chain | WikiPathways | WP111 | 92 | 33 | 5312 | 837 |
NDUFA5,COX5B,NDUFV2,COX15,NDUFS1,NDUFB6,UQCR10,COX4I1,NDUFA4,ATP5F1B,ATP5PF,SDHA,NDUFS7,NDUFS4,NDUFV1,NDUFA2,NDUFB4,NDUFS8,NDUFB9,NDUFA3,ATP5IF1,NDUFA7,NDUFB1,ATP5MF,SLC25A5,SDHB,ATP5MC3,COX7A2L,COX8A,COX5A,UQCRH,ATP5F1A,NDUFS5 |
| 1.595e-06 | -13.35 | regulation of cellular amide metabolic process | biological process | GO:0034248 | 424 | 101 | 17256 | 2622 |
SARNP,RPS6KA1,FAM129A,PPP1R15B,EIF3D,RBM8A,DNAJC24,YTHDF3,EIF1B,RBM4,APP,PAIP1,PAIP2,PRNP,PA2G4,EIF4A3,METTL14,MRPS27,EIF5,MTPN,PLK3,POLR2G,NCK1,CDC123,AKT2,BTG2,RPL38,POLR2D,CIRBP,SOX4,RPS9,SERP1,EIF3H,EIF3K,GEMIN5,MKNK1,EIF4ENIF1,TMED10,HNRNPR,RPS14,CLU,ROCK1,MAPK1,ZNF598,UNK,MIF4GD,AGO2,PRKAA1,HABP4,DHX9,TIA1,SECISBP2,EIF2AK4,RGS2,CNOT11,METTL3,FOXO3,CNOT3,FASTKD3,TIGAR,MEX3C,DAPK1,LTN1,RBM3,GLE1,CNOT6L,STAT3,NSUN4,PABPC1,EIF5A,SAMD4B,CYFIP1,COA3,RHOA,ILF3,EIF2AK1,EIF2A,FXR1,CYFIP2,EIF4H,EIF4G2,PICALM,DAPK3,MAPK3,CNOT9,TSC1,EPRS,UPF1,SYNCRIP,ORMDL2,LRPPRC,KHSRP,CTSA,SAMD8,TCOF1,SNRNP70,PGAM1,CPEB2,TOB1,PURA,RNF139 |
| 1.601e-06 | -13.34 | WHITFIELD_CELL_CYCLE_LITERATURE | MSigDB lists | WHITFIELD_CELL_CYCLE_LITERATURE | 44 | 20 | 17377 | 2626 |
PLK1,PSRC1,NASP,CENPF,RRM1,RRM2,SLBP,RACGAP1,CDC6,BRCA1,CCNF,MCM2,CCNB1,CDKN2C,CCNA2,PCNA,BIRC5,MSH2,E2F1,CCNB2 |
| 1.604e-06 | -13.34 | GSE16385_MONOCYTE_VS_12H_ROSIGLITAZONE_IFNG_TNF_TREATED_MACROPHAGE_DN | MSigDB lists | GSE16385_MONOCYTE_VS_12H_ROSIGLITAZONE_IFNG_TNF_TREATED_MACROPHAGE_DN | 180 | 52 | 17377 | 2626 |
CTDP1,NSMCE4A,DNMT3A,LUZP1,RRP15,SUCLG1,GNPDA1,TSC22D3,DNAJB2,TOR3A,TRMT6,CHIC2,SLC35B1,PABPC4,COPB2,SIAH1,LRRC8D,DAD1,MRPL54,ALDH18A1,FBL,MRPL11,MYBL1,ABCC1,TSHZ1,PPP3CA,FTL,RHOA,MAPRE2,TSPYL4,ELL2,TSPAN31,NSUN2,WDR18,ODC1,ERC1,AKAP1,PPP2CA,TPD52L2,FBXO21,TRIM26,L3MBTL3,NFIL3,MYO18A,STAT1,E2F1,SLAIN1,ASNA1,BEND3,BTF3,EHD4,COIL |
| 1.614e-06 | -13.34 | Znf_RING/FYVE/PHD | interpro domains | IPR013083 | 446 | 104 | 18492 | 2768 |
MIB2,TRIM41,ASH1L,TRAF7,KMT2E,KDM4A,PHRF1,TRIM11,XIAP,USP39,ZFYVE21,NSD3,RUFY1,TCF19,TRIM65,ANKIB1,RNF103,USP5,FANCL,CYHR1,MDM2,KDM2A,BRPF3,SIAH1,MTMR4,ZFYVE27,INTS12,TTC3,MARCH2,RNF19A,RNF26,RNF169,RLIM,PRPF19,TRIM8,BAZ2A,RBX1,RNF25,PCGF6,LNX2,TOPORS,USP22,BRCA1,DIDO1,KMT2C,TRIM28,PLEKHF2,TRIM4,TRIM47,RAD18,CHD3,NSMCE2,UHRF2,RNF38,BAZ1B,TRIM32,TRIM52,TRAF5,USP13,PHF23,SHPRH,BRAP,CBLL1,ZNRF3,UBE4A,RFWD3,RNF121,MEX3C,RNFT1,ZNRF2,PHF14,PPIL2,LTN1,PIKFYVE,RNF135,FBXL19,GTF2H2,LRSAM1,SYTL3,RNF5,PHF20L1,PHF10,TRAFD1,LONRF3,ZMYND11,RFFL,SYVN1,UBE4B,PCGF1,PHF6,MTMR3,HGS,COMMD3-BMI1,TRIM26,DTX4,SIAH2,PIAS2,PML,KMT2B,USP20,ZMIZ1,RNF14,RNF139,RNF114 |
| 1.623e-06 | -13.33 | TPD52L2 (tumor protein D52 like 2) | protein interactions | 7165 | 70 | 28 | 17029 | 2761 |
METTL1,TP53RK,MRPS2,GABPA,DRAP1,ACTR3,VAV2,EZR,RANGAP1,EFL1,UBQLN2,ARPC1A,MTR,APP,TARS,CLNS1A,SH3GLB1,RPA2,SEC31A,TPD52L2,PPM1G,BTF3L4,OGT,ANP32A,PTGES3,AHCYL1,PDIA6,SSSCA1 |
| 1.623e-06 | -13.33 | K8.1 (envelope glycoprotein) | protein interactions | 4961469 | 70 | 28 | 17029 | 2761 |
COX5B,NDUFV2,COA3,ASPM,UBR2,ATP6V0A1,COX4I1,SYVN1,CHCHD6,FAM8A1,NDUFV1,POLE,THADA,OSBPL8,COX7A2L,FUT8,HADHB,GLG1,COX8A,ATE1,LTN1,NDUFB9,NDUFS5,NDUFA3,ATP6V0D1,C2CD5,MTX2,HIGD2A |
| 1.623e-06 | -13.33 | Smn1 (survival motor neuron 1) | protein interactions | 20595 | 70 | 28 | 17029 | 2761 |
NOP9,TXN,RAF1,SNRPB,TIA1,DDX20,GLUD1,COX4I1,SNRPD3,VKORC1,CLNS1A,GEMIN5,SLC38A5,TIMM23,HADHB,GEMIN6,ATP5F1A,GEMIN4,FBL,SNRNP70,PTDSS1,COIL,STRAP,CDKN2A,RNF5,TIMM50,ESYT2,GEMIN7 |
| 1.629e-06 | -13.33 | Respiratory electron transport | REACTOME pathways | R-HSA-611105 | 92 | 34 | 10287 | 1696 |
COX5B,NDUFA5,NDUFV2,NDUFS1,NDUFB6,NDUFAF2,UQCR10,NDUFA4,COX4I1,CYCS,SDHA,NDUFS7,NDUFS4,NDUFAF6,NDUFV1,NDUFA2,NDUFB4,NDUFB9,NDUFS8,CYC1,NDUFA3,TIMMDC1,TMEM126B,COQ10B,NDUFA7,NDUFB1,SDHB,COX7A2L,NDUFA11,COX8A,LRPPRC,COX5A,UQCRH,NDUFS5 |
| 1.634e-06 | -13.32 | LAU_APOPTOSIS_CDKN2A_UP | MSigDB lists | LAU_APOPTOSIS_CDKN2A_UP | 55 | 23 | 17377 | 2626 |
PDCD6IP,TNFAIP3,DAP,MYBL2,BCLAF1,CYCS,PAWR,BRCA1,BCL2L1,RHOB,FADD,CFLAR,FAS,PCNA,PDCD6,SIAH1,E2F1,CDKN1B,CLU,TP53BP2,TRAF5,PDCD11,PDCD4 |
| 1.636e-06 | -13.32 | structural constituent of ribosome | molecular function | GO:0003735 | 159 | 48 | 17224 | 2647 |
RPS15,MRPL9,RPS2,CYLD,RPLP2,MRPL42,MRPS2,MRPS15,RPL15,MRPL19,RPL23A,RPL11,RPL17,MRPL34,RPL19,MRPL21,MRPL11,RPL22L1,MRPL32,MRPL57,RPL29,RPL35,MRPL43,RPL6,MRPL12,RPL8,RPL38,RPS10,RPS24,MRPL16,NDUFA7,RPL27A,MRPS14,RPS9,RPSA,RPL36,RPL37,MRPL2,DAP3,RPL32,MRPL55,RPS27A,RPS14,MRPL27,RPLP1,MRPL13,RPS26,MRPL3 |
| 1.647e-06 | -13.32 | Nucleotide Excision Repair | REACTOME pathways | R-HSA-5696398 | 112 | 39 | 10287 | 1696 |
USP7,POLR2K,XAB2,SUMO2,CHD1L,INO80E,UBE2I,RAD23A,RPA2,PCNA,RAD23B,XPA,COPS7B,TCEA1,AQR,GTF2H2,PRPF19,COPS8,ERCC1,HMGN1,POLR2I,RFC3,POLR2L,POLR2G,POLK,RBX1,PPIE,POLR2D,RFC2,POLR2A,RPA1,POLE,POLR2J,RPS27A,ACTB,COPS6,YY1,ZNF830,DDB1 |
| 1.647e-06 | -13.32 | CDK9 (cyclin dependent kinase 9) | protein interactions | 1025 | 200 | 59 | 17029 | 2761 |
CTDP1,IMMT,TRIP12,CLSPN,CUL1,CSNK2A1,CDC73,GTF2F1,HNRNPA2B1,CCNK,RB1,RPN1,MDM2,PIN1,IL6ST,MRPS27,MSH2,CTR9,YBX1,AFF1,MDFIC,TCEA1,STAT3,CDK12,ILKAP,PCBP2,SMC4,TERF2,CDC37,CDC5L,BRD4,ELL2,PRKDC,MYBL2,RRM2,BRCA1,SMC2,PLEC,CCT8,TRIM28,MATR3,POLR2A,SUPT16H,CNOT9,SEC31A,PAF1,SMAD2,ATP1A1,SYNCRIP,HINT1,HNRNPR,DDX5,XRCC3,FKBP5,KPNA2,RUVBL2,SMAD1,SMAD4,TERF1 |
| 1.675e-06 | -13.30 | VPS4B (vacuolar protein sorting 4 homolog B) | protein interactions | 9525 | 45 | 21 | 17029 | 2761 |
CHMP2A,UBQLN4,PDCD6IP,UBXN1,BABAM1,VPS45,CUL3,UBE4B,RAB5B,BIRC2,CHMP4A,NSF,PPP1R8,TTC9C,VPS4A,TTLL12,AHCYL1,IGBP1,SSSCA1,HTRA2,USP34 |
| 1.690e-06 | -13.29 | GSE17721_POLYIC_VS_CPG_24H_BMDC_DN | MSigDB lists | GSE17721_POLYIC_VS_CPG_24H_BMDC_DN | 185 | 53 | 17377 | 2626 |
BCCIP,GCLM,MAPRE1,MUT,NDUFB6,AGRN,MECP2,B4GALT1,TM9SF3,LYN,CFLAR,RPA2,RRN3,NUS1,VASP,AHCTF1,VMP1,AHSA1,INTS1,ANKRD13C,TAGLN2,RNF19A,OSTC,MAML1,IMPA2,MRPL32,EIF3L,MLEC,LACTB,MYBL2,MKI67,NUTF2,TMEM147,TARS,NUCB1,CDC16,UEVLD,OAZ2,COX8A,ACLY,PGRMC1,COX5A,ADAM9,ANP32E,CHEK2,TMEM159,XRCC4,PITRM1,ARHGAP23,PGAM1,ZNF598,MRPL3,SLC25A33 |
| 1.690e-06 | -13.29 | GSE28408_LY6G_POS_VS_NEG_DC_DN | MSigDB lists | GSE28408_LY6G_POS_VS_NEG_DC_DN | 185 | 53 | 17377 | 2626 |
RPS2,HNRNPAB,HEXB,NUP54,UCK2,HAUS4,POMP,GYG1,SRRT,POLR3K,PIP4K2A,FBXO5,MBD4,KIFC1,CD59,OIP5,PSMA6,ATP2A2,DPYSL2,KIF14,H2AFY,MRPL48,MRPL11,CTDSP2,SEH1L,TACC3,FDFT1,ACSL5,PSRC1,FAM49B,PPT1,RFXANK,PSMG1,MRPL16,SHCBP1,RFC2,DDX39A,RPSA,RAD54B,CHAF1A,PSMC4,PRIM1,KIF18A,BIRC5,RBMX,H2AFX,PRMT7,UQCRH,ANP32E,CLU,PDXK,YWHAH,MZT2B |
| 1.690e-06 | -13.29 | KASLER_HDAC7_TARGETS_1_UP | MSigDB lists | KASLER_HDAC7_TARGETS_1_UP | 185 | 53 | 17377 | 2626 |
WSB2,CTU2,CYTIP,DNMT3A,TMUB1,MRPS2,POC1A,RPS6KA1,CUTA,B4GALT1,ANKRD23,ANKRD39,FARSA,IRF4,FBXL6,ATP2A2,DAD1,PIN1,AP1M1,H2AFY,ARHGEF2,GLTP,BCL2,CNNM3,STAT3,ASB6,ANKRD9,NCOA2,GM2A,TGFB1,CLPTM1,TDP1,PIGT,GALC,TIMMDC1,CYP20A1,SSR2,WDR82,MIER2,SYVN1,TOMM40,CYFIP2,SMAP2,DAPK3,AKAP1,TMEM41A,IDE,HSPBP1,CAPN7,AEN,PPP5C,B4GALT3,CDK2 |
| 1.700e-06 | -13.29 | Hnrnpa3 (heterogeneous nuclear ribonucleoprotein A3) | protein interactions | 229279 | 32 | 17 | 17029 | 2761 |
HNRNPAB,DHX9,MRPS10,FAM50B,SLC35B1,SAFB2,MATR3,HNRNPA2B1,GATC,HNRNPR,PTEN,HNRNPH3,SAFB,ZNF326,RBM12B,HNRNPDL,HNRNPM |
| 1.738e-06 | -13.26 | GO_CELL_CYCLE_G1_S_PHASE_TRANSITION | MSigDB lists | GO_CELL_CYCLE_G1_S_PHASE_TRANSITION | 108 | 36 | 17377 | 2626 |
POLA2,GPR132,MCM10,CDT1,DBF4,CUL1,ORC1,CRLF3,FBXO5,CDKN2C,RPA2,RB1,PCNA,MCM5,PPP6C,CDKN1B,ORC3,CAMK2G,PLK3,PPP3CA,BRD4,PRIM2,CUL3,RRM2,CDC6,PKMYT1,MCM2,PRIM1,RPA1,POLE,E2F4,CDCA5,E2F1,ITGB1,CDK2,CDKN2A |
| 1.738e-06 | -13.26 | GO_G1_S_TRANSITION_OF_MITOTIC_CELL_CYCLE | MSigDB lists | GO_G1_S_TRANSITION_OF_MITOTIC_CELL_CYCLE | 108 | 36 | 17377 | 2626 |
POLA2,GPR132,MCM10,CDT1,DBF4,CUL1,ORC1,CRLF3,FBXO5,CDKN2C,RPA2,RB1,PCNA,MCM5,PPP6C,CDKN1B,ORC3,CAMK2G,PLK3,PPP3CA,BRD4,PRIM2,CUL3,RRM2,CDC6,PKMYT1,MCM2,PRIM1,RPA1,POLE,E2F4,CDCA5,E2F1,ITGB1,CDK2,CDKN2A |
| 1.739e-06 | -13.26 | GSE27859_DC_VS_CD11C_INT_F480_HI_MACROPHAGE_DN | MSigDB lists | GSE27859_DC_VS_CD11C_INT_F480_HI_MACROPHAGE_DN | 148 | 45 | 17377 | 2626 |
PIGM,TOMM20,MRPL39,MRI1,SNX15,CUTA,TMX3,FLOT1,SIKE1,DCUN1D4,TUBGCP2,FBXO5,SLC25A36,CALM2,ABL2,NEK6,INPP5A,SUCLG2,SLC35C2,SGCB,CLN6,CGGBP1,MYO5A,ALDH9A1,SMC4,TERF2,CCT2,RPL29,NLN,AMDHD2,AP4E1,MATR3,TARS,EIF3H,ABHD5,HMGN2,DAP3,ELMO1,ZHX1,PRMT7,ANP32E,ASNA1,PDXK,PITRM1,SVIP |
| 1.740e-06 | -13.26 | PPP2R2B (protein phosphatase 2 regulatory subunit Bbeta) | protein interactions | 5521 | 52 | 23 | 17029 | 2761 |
CCT2,IER2,SKA3,ZCCHC8,DYNLL1,RAF1,RAC1,TUFM,CUL3,MCM2,CCT8,TRIM28,PPP2CA,ZBTB21,CDCA4,SYNM,KLHL15,ATXN2L,FAM122A,CHEK2,PTPDC1,MYO9A,ZC3HAV1 |
| 1.748e-06 | -13.26 | mitotic nuclear envelope disassembly | biological process | GO:0007077 | 44 | 20 | 17256 | 2622 |
PLK1,NDC1,NUP188,RAE1,NUP54,NUP155,CCNB1,LMNA,NUP205,NUP210,NEK6,BANF1,NUP107,NUP62,NUP153,CCNB2,NUP58,NUP85,SEH1L,AAAS |
| 1.751e-06 | -13.26 | IKBKE (inhibitor of nuclear factor kappa B kinase subunit epsilon) | protein interactions | 9641 | 74 | 29 | 17029 | 2761 |
DDX58,CCT2,LARS,CYLD,TNFAIP3,BIRC3,XIAP,SIKE1,TOPORS,IRF3,SND1,AZI2,BIRC2,CCT8,KTN1,IRF5,EPRS,ATIC,TANK,ACLY,PML,LRPPRC,FKBP5,TICAM1,MAVS,RUVBL2,PDIA6,PABPC1,CDC37 |
| 1.751e-06 | -13.26 | NDUFA12 (NADH:ubiquinone oxidoreductase subunit A12) | protein interactions | 55967 | 74 | 29 | 17029 | 2761 |
NDUFA5,COX15,NDUFV2,IMMT,NDUFS1,NDUFB6,TIMMDC1,ZNF768,ERLIN1,VDAC2,NDUFA4,NDUFA7,ATP5F1B,NDUFS7,NDUFS4,SDHB,RPN1,NDUFV1,NDUFA2,NDUFB4,NDUFA11,MPV17,NDUFB9,UQCRH,ABCD1,NDUFS8,CYC1,NDUFS5,APOOL |
| 1.756e-06 | -13.25 | JOHNSTONE_PARVB_TARGETS_2_UP | MSigDB lists | JOHNSTONE_PARVB_TARGETS_2_UP | 130 | 41 | 17377 | 2626 |
RAB11B,DLGAP4,SLC4A2,BCL2L1,ASXL2,CMTM6,HLA-A,MOAP1,CALM2,FKBP1A,APLP2,AKR1B1,SCAMP4,CITED2,GNAI2,CFL1,SLC25A1,SPTAN1,CLPTM1,TGFB1,PPP1R9B,DCAF6,TNFAIP3,GALC,EMB,OAF,WBP2,OGDH,NDUFB1,LY6E,ISG15,GPR137,HLA-B,HGS,AGPAT2,SNAP29,TFE3,ERGIC3,ACTB,USP11,BRD9 |
| 1.757e-06 | -13.25 | ATR (ATR serine/threonine kinase) | protein interactions | 545 | 122 | 41 | 17029 | 2761 |
CLSPN,AP1B1,BLM,FANCI,DTL,RPA2,CDKN2C,PA2G4,MTMR4,MTA1,ARHGEF1,XPA,MSH2,CREB1,MCPH1,NCOA2,MSH6,CDC5L,TELO2,AATF,MTA2,CDC6,FAM133B,BRCA1,DCLRE1C,MCM2,RHEB,RPA1,XRCC5,HSPA4,UPF1,PML,H2AFX,UHRF2,E2F1,USP20,CHEK2,CCNB2,HDAC2,CDKN2A,ATMIN |
| 1.760e-06 | -13.25 | respiratory electron transport chain | biological process | GO:0022904 | 99 | 34 | 17256 | 2622 |
COX15,COX5B,NDUFA5,NDUFV2,NDUFS1,NDUFB6,NDUFAF2,UQCR10,MECP2,SLC25A12,NDUFA4,COX4I1,CYCS,SDHA,NDUFS7,NDUFS4,NDUFV1,NDUFA2,NDUFB4,NDUFB9,NDUFS8,CYC1,NDUFA3,NDUFA7,NDUFB1,TAZ,POLG2,SDHB,NDUFA11,COX7A2L,COX8A,COX5A,UQCRH,NDUFS5 |
| 1.772e-06 | -13.24 | KAUFFMANN_MELANOMA_RELAPSE_UP | MSigDB lists | KAUFFMANN_MELANOMA_RELAPSE_UP | 59 | 24 | 17377 | 2626 |
TDP1,RAD51AP1,CENPF,PTTG1,RRM2,CDC6,BRCA1,SMC2,BLM,RFC2,CHAF1A,XRCC5,PCNA,RAD18,NEIL3,XRCC2,MSH2,CHEK2,GTF2H2,OGG1,TERF1,MSH6,SMC4,POLQ |
| 1.772e-06 | -13.24 | MORF_MSH2 | MSigDB lists | MORF_MSH2 | 59 | 24 | 17377 | 2626 |
SNRNP200,POLR2I,NUP188,HNRNPAB,RRM1,MCM2,DDX39A,PRPSAP1,CLNS1A,CHAF1A,SRSF1,RPA1,HNRNPA2B1,PCNA,IARS,PARG,LRPPRC,MSH2,BAZ1B,RUVBL2,HDAC2,MSH6,SSRP1,NUDC |
| 1.773e-06 | -13.24 | GSE16266_CTRL_VS_HEATSHOCK_AND_LPS_STIM_MEF_DN | MSigDB lists | GSE16266_CTRL_VS_HEATSHOCK_AND_LPS_STIM_MEF_DN | 190 | 54 | 17377 | 2626 |
MMACHC,IER2,KRBA1,ARID2,PIGQ,BABAM1,UROD,CTCF,UCK1,UBE4A,CDIPT,WDR5,PIP5K1C,FERMT3,MLX,COQ4,DDA1,PDCD2,GPATCH1,CLTB,GNAI2,LYPLA2,MED22,ALDH9A1,TMEM160,LDHB,COPS8,PPIF,ENPP4,CCT2,CYTH1,DEAF1,TIMP2,RBX1,MFNG,EMP3,ITM2A,COG1,OGDH,CYFIP2,CCNF,RPL36,WAS,SERF2,DDOST,NDUFA11,PPM1G,PRDX5,RPLP1,TMEM219,FAM122A,RUFY3,GPATCH4,SSRP1 |
| 1.773e-06 | -13.24 | GSE7831_CPG_VS_INFLUENZA_STIM_PDC_1H_UP | MSigDB lists | GSE7831_CPG_VS_INFLUENZA_STIM_PDC_1H_UP | 190 | 54 | 17377 | 2626 |
PRKAB1,SMAP1,SARNP,H2AFZ,KIAA0100,SF3B1,DAP,SRSF6,PTP4A3,TOP2B,ORC1,LANCL1,CDK11B,ETS1,FERMT3,KRR1,PHC2,GOLM1,ERH,ZKSCAN1,RABGAP1L,LPIN2,ZNF746,ATP6V0A2,PDCD2,SLC27A4,PRADC1,MTX2,ASB6,RPRD1B,FTSJ3,SMC4,RPAP3,GABPA,MRPS10,KRAS,MEF2D,DNAJA1,AZI2,PEF1,MAP3K4,GOLGA4,IDE,AHNAK,PEX5,PPP2R5A,LUC7L3,CAPN7,CRCP,COIL,ABCA1,VPS29,HDAC2,PFKP |
| 1.773e-06 | -13.24 | GSE9650_GP33_VS_GP276_LCMV_SPECIFIC_EXHAUSTED_CD8_TCELL_DN | MSigDB lists | GSE9650_GP33_VS_GP276_LCMV_SPECIFIC_EXHAUSTED_CD8_TCELL_DN | 190 | 54 | 17377 | 2626 |
WSB2,SLC30A9,PRKAB1,C9orf78,NDUFS1,HNRNPAB,IVNS1ABP,DAP,PTTG1,CDCA8,TIA1,GTF3A,TWF2,GGPS1,MIEN1,PITHD1,FOXO3,SDHA,VPS25,MLX,INTS7,TBC1D14,AP1M1,MSH2,HADHB,ANXA5,CYC1,METTL9,LMAN1,SLC35A1,PPA1,SEH1L,HNRNPM,SLC39A9,PRIM2,SMU1,RNPS1,CIRBP,DNAJC9,GLO1,GALK2,NUTF2,TXNL4A,FOXRED1,CLNS1A,YIF1A,TMEM168,STK38,PPM1G,ARNTL,LY75,SSNA1,ATF6,SNAPIN |
| 1.773e-06 | -13.24 | GSE2405_0H_VS_24H_A_PHAGOCYTOPHILUM_STIM_NEUTROPHIL_UP | MSigDB lists | GSE2405_0H_VS_24H_A_PHAGOCYTOPHILUM_STIM_NEUTROPHIL_UP | 190 | 54 | 17377 | 2626 |
UBE2D3,ZNF296,RPS2,RPLP2,DAP,TKT,TM9SF3,CHCHD2,DAZAP2,CSNK1A1,RAPGEF6,RPL11,FERMT3,RPL23A,IRF4,DECR1,SUB1,NUP210,RPL17,BTF3L4,YBX1,RPL19,CORO1A,RPL22L1,S100A6,ACSL5,RPL35,HNRNPF,RPL38,RPL6,RPS10,PSMA1,RPL27A,EIF4G2,RPS9,ISG15,PRDX1,RPSA,EIF3H,RPL36,RPL37,PDLIM1,HINT1,RPS14,PRDX5,COX5A,ACTB,MRFAP1L1,SNRPG,NDUFS5,CLU,ATP6V1C1,RPS26,OAZ1 |
| 1.773e-06 | -13.24 | GSE17721_CTRL_VS_CPG_0.5H_BMDC_UP | MSigDB lists | GSE17721_CTRL_VS_CPG_0.5H_BMDC_UP | 190 | 54 | 17377 | 2626 |
TMUB1,ADD1,AGRN,IVNS1ABP,PTTG1,TKT,RRM1,KIF23,ASAH1,OAT,MAPK14,RCOR3,TMEM165,FAM8A1,APP,SSR1,UBXN2A,NFATC3,C18orf32,TNPO2,ANKRD13C,MRPL11,RNF135,MAML1,SLC35A1,NUP85,LYPLA2,HP1BP3,RPAP3,CPNE1,UBQLN4,FAM49B,ERF,PPP1R21,POLR2D,PIP4K2C,NUSAP1,UHRF1BP1,MCFD2,SOX4,ANKRD46,AKAP1,HHEX,FBXO28,GOLGA7,DGCR8,ACLY,ZNF436,QRSL1,CHMP4B,GALNT10,HEXA,MYL12B,ABCA1 |
| 1.778e-06 | -13.24 | YGCGYRCGC_UNKNOWN | MSigDB lists | YGCGYRCGC_UNKNOWN | 298 | 76 | 17377 | 2626 |
IMMT,HNRNPAB,EIF3D,UROD,ALKBH5,NIPA2,CD320,SLC25A37,CALM2,KDM2A,ATP2A2,AKAP8,TTC9C,FIZ1,POP7,PDS5B,GPD1L,PCBP2,CFL1,FYTTD1,ZNF524,TRIM8,ATP13A1,AATF,EID1,GOPC,TAOK1,HSDL1,DNAJA1,PBRM1,PKMYT1,SERP1,UBTF,HNRNPR,VPS26B,ATXN2L,RNF38,ARRB2,PDCD2L,ZFP91,SRSF6,MECP2,ADO,DLGAP4,KLF13,SLC25A12,RAB6A,AP3S1,TFRC,TFAP4,PSMD2,MLX,RNFT1,FUT8,ANP32A,TIMELESS,GEMIN4,ST8SIA2,SPTAN1,RHOA,BCLAF1,FAM133B,EIF2A,C9orf40,ARL17A,GNAS,MTMR3,MTHFD2,GOLGA2,PALB2,SYNCRIP,RBBP4,NR2F2,PLOD3,NUDT3,TIGD2 |
| 1.802e-06 | -13.23 | RPL8 (ribosomal protein L8) | protein interactions | 6132 | 196 | 58 | 17029 | 2761 |
RPS15,RPS2,CYLD,EWSR1,NOP2,RPLP2,MECP2,RPL15,CUL1,EBNA1BP2,UBE2I,PABPC4,RPL11,RPL23A,FGFR3,PA2G4,EIF4A3,RPL17,HUWE1,RBM34,ZNF746,RPF2,RPL19,UPF2,TARDBP,ZNF770,FTSJ3,STAU1,RPL29,RPL35,DDX24,ZNF512,RPS10,RPL6,TUFM,RIOX2,CUL3,ILF3,RPL38,RPS24,BRCA1,RPL27A,RPS9,RPSA,CAND1,RPL36,CCDC86,RPL32,RPS14,H2AFX,COPS6,RRS1,CDK2,RPS26,ZC3HAV1,NUDT3,ZBTB24,CCDC137 |
| 1.810e-06 | -13.22 | MARTINEZ_TP53_TARGETS_UP | MSigDB lists | MARTINEZ_TP53_TARGETS_UP | 572 | 128 | 17377 | 2626 |
ZBED3,HNRNPAB,ADD1,TMEM109,CCNL2,GIT2,PAPOLA,USF1,IL6ST,DNM2,AP2B1,TCEA1,MARCH2,MOB1A,ASB6,DRAM2,ABCC5,USP34,PBK,SREK1,PITPNB,SOX4,RAB2B,CLNS1A,EIF3A,DPYSL3,TPP2,ST3GAL2,ACTB,DVL1,CHPT1,UBE2D3,RECQL,SCOC,RRM1,TIA1,MEF2A,RACGAP1,DNAJB1,VPS25,SPAG5,WDR48,NDUFS4,C4orf3,CTR9,TNPO3,ACAD8,NSUN4,MORC3,SIGMAR1,RDH10,AMD1,ZNF574,SEPT8,ITM2A,KRAS,MTX1,EIF4H,PTPRF,CAT,GNAS,PFDN5,NAP1L1,FNTA,PCM1,NSF,RBBP4,RNF14,PDLIM5,MRPL3,RNF114,TCF12,TMEM106C,IMMT,PTTG1,UCK1,NIT2,DUSP22,BCAP31,APP,RRN3,PRKD3,SAR1A,INTS12,LMAN1,ATF2,ARL5A,CTDSP2,MAPRE2,PFKFB3,GLO1,BICD2,SERP1,IDE,JAK1,ACYP1,LMBR1,RBMS1,ZNF445,CASP6,SRGN,LANCL1,PIP4K2A,TUBGCP2,TFRC,FERMT3,ADD3,ZNF260,IFT46,PDPK1,PPP3CA,TIMMDC1,ABCF2,ILF3,PRKAR1B,KIF11,SPPL2B,PRDX1,ZFR,RPA1,GNA12,TWSG1,ACOX1,ZNF330,CTBS,ASNA1,PSAP,HIPK3 |
| 1.815e-06 | -13.22 | GSE13547_2H_VS_12_H_ANTI_IGM_STIM_ZFX_KO_BCELL_DN | MSigDB lists | GSE13547_2H_VS_12_H_ANTI_IGM_STIM_ZFX_KO_BCELL_DN | 162 | 48 | 17377 | 2626 |
MIF,INTS2,MCM10,TMBIM4,CENPF,TPX2,CDCA3,RRM1,KIF23,RACGAP1,PMF1,ORC1,NCKAP1,TUBGCP2,TFRC,SPAG5,PA2G4,CCDC50,BANF1,RPF2,YBX1,RBM3,AHCY,TAGLN2,MRPL48,SEH1L,TACC3,GINS1,SEC61B,RAD51AP1,EMB,KIF15,MKI67,RRM2,CDC6,AURKB,SMC2,KIF11,HMGN2,ADSS,BIRC5,DCK,PSMD8,NEIL3,NRM,MRPL27,CCNB2,AP2S1 |
| 1.819e-06 | -13.22 | respiratory chain complex I | cellular component | GO:0045271 | 45 | 20 | 18223 | 2701 |
NDUFA5,NDUFV2,NDUFS1,NDUFB6,DMAC2,NDUFA4,NDUFA7,NDUFB1,FOXRED1,PARK7,NDUFS7,NDUFS4,NDUFV1,NDUFA2,NDUFB4,NDUFA11,NDUFS8,NDUFB9,NDUFS5,NDUFA3 |
| 1.819e-06 | -13.22 | mitochondrial respiratory chain complex I | cellular component | GO:0005747 | 45 | 20 | 18223 | 2701 |
NDUFA5,NDUFV2,NDUFS1,NDUFB6,DMAC2,NDUFA4,NDUFA7,NDUFB1,FOXRED1,PARK7,NDUFS7,NDUFS4,NDUFV1,NDUFA2,NDUFB4,NDUFA11,NDUFB9,NDUFS8,NDUFS5,NDUFA3 |
| 1.819e-06 | -13.22 | NADH dehydrogenase complex | cellular component | GO:0030964 | 45 | 20 | 18223 | 2701 |
NDUFA5,NDUFV2,NDUFS1,NDUFB6,DMAC2,NDUFA4,NDUFA7,NDUFB1,FOXRED1,PARK7,NDUFS7,NDUFS4,NDUFV1,NDUFA2,NDUFB4,NDUFA11,NDUFS8,NDUFB9,NDUFS5,NDUFA3 |
| 1.822e-06 | -13.22 | GSE7509_UNSTIM_VS_TNFA_IL1B_IL6_PGE_STIM_DC_UP | MSigDB lists | GSE7509_UNSTIM_VS_TNFA_IL1B_IL6_PGE_STIM_DC_UP | 176 | 51 | 17377 | 2626 |
RHOG,CMAS,PDCD6IP,NOP2,ANXA6,URB2,TKT,STARD7,DHX8,RACGAP1,NANS,ITGB5,LMNA,DDX56,GART,RNASEK,SLC26A2,MVP,HDHD2,NAGPA,RFC3,RHOBTB3,GUK1,HARS,FAM118B,WDR18,SLC16A7,ADSL,PSMG1,AURKB,EDEM2,SHCBP1,TRIM28,NCDN,RPA1,PI4K2A,PLD3,OSBPL11,HSPBP1,ACOX1,TBL3,PPA2,PRMT7,SAMD8,PPP5C,ABCA1,MRPL3,CHID1,CAPN1,DDB1,SLC25A33 |
| 1.826e-06 | -13.21 | rectum | COSMIC cancer mutations | rectum | 16329 | 2480 | 17385 | 2587 |
HECA,ZBTB10,ABCC10,HEXB,TGOLN2,CCNL2,FBXO22,EEF2K,THAP4,RAD23B,ATP13A3,DNM2,ZNRD1,FTSJ3,USP34,CCDC57,ERCC1,NRAS,EHMT1,KIF15,HNRNPF,WDHD1,MIER2,DIDO1,MCM2,RAB22A,SMAD2,MID1IP1,RPS27A,MYO18A,OGT,MPV17,COX5A,SMAD1,ZNF75A,ANXA11,SLC25A33,SEC61G,GGA1,MUM1,CCZ1,TRIO,CUTA,RAB23,HAUS4,EIF2AK4,APH1B,PARN,CDC73,MYL6B,ATG4A,ERV3-1,PDXP,SMC3,GEMIN4,MVP,NUP85,PPP6R1,PABPC1,NSUN4,PPA1,IFRD1,AGGF1,FOXK1,RBM42,GTPBP4,MAP7D1,MRPL16,ELK1,EIF4H,RDH11,MAGED2,KPNA1,ETS2,TYW5,WIPI2,RUFY3,PDLIM5,ACSF2,EXOC3,RHOG,STARD7,C5orf30,VTI1A,SLC35B2,INO80E,RCOR3,LCLAT1,CPNE3,RBM23,ZNF420,AHCTF1,TBC1D22A,TBC1D14,GMEB1,NSFL1C,SEPT11,GPD1L,ZC3H3,ARL5A,PDCL3,SNX8,ERMP1,EID1,IDH3A,POLR2D,HTATIP2,MEF2D,TMEM147,GSTCD,TANC1,MAT2A,VPS26B,NSMCE2,CORO1C,CAMKMT,PPP5C,PITRM1,TUBB,COMMD10,ZNF445,SRSF6,HABP4,CCM2,FLOT1,BTN3A1,ATG2B,ABHD14B,PPP1R3B,GOLM1,ZBTB45,HUWE1,ZNF260,NAA50,ANXA5,LTN1,UBE3B,NAP1L4,ZNF710,ST8SIA2,MED22,SPTAN1,STAU1,DDX24,TCTEX1D2,TACC1,MRS2,LDHA,HEBP2,LLPH,RAB3IP,TTC33,PICALM,SH3BP5,SLC19A1,ACOX1,FAM3C,AEN,PARP10,YWHAH,THAP5,GPATCH4,FAM129A,TRIM11,YTHDC2,SNX15,RBM8A,ENSA,NENF,SND1,RUFY1,TRIM65,ZER1,PRNP,KRR1,RAB8A,NUP210,NT5DC1,NOC2L,EIF5,TACC3,VPS13B,PTPN18,MIOS,MBLAC2,SNRPB,CDC6,UTP3,PBRM1,ODC1,USP21,TRAM2,FBXO28,BCL7C,ARRDC1,ADAM9,DVL1,NUMB,ZNF564,FUBP1,C1orf74,PARP12,ZCCHC9,CENPF,LAMTOR3,CHCHD2,NCKAP1,LYRM2,RSAD1,TNS3,SUB1,RINL,SSBP3,KIF13B,MBD2,XPA,AHCY,RBM3,GLE1,MRPL48,LRSAM1,HDHD2,NTPCR,NSDHL,AMD1,CAMSAP1,ZNF761,METTL22,ICAM2,STYXL1,APPL1,BBS12,RXRB,SDHB,PCM1,GALNT2,TMEM168,NLRC5,RUVBL2,MYO9A,BTBD10,CCNB2,USP7,GLT8D1,RPLP2,SUCLG1,ARID2,TMX4,SLC2A1,ATP6V1B2,PCBP1,LYN,BCAP31,VAV1,TMEM69,MRPL50,PSMA6,ZNF473,ZNF302,BRPF3,TARDBP,BCAP29,CTDSP2,PRPF19,PPIF,KDM3B,MND1,CLCN3,BIRC3,RAB7A,PPIE,CHMP2B,VDAC1,EIF3H,GLOD4,IDE,DHX16,UHRF2,CHMP4B,XRCC3,PARD3,BCL2L12,C19orf53,MCM10,KLHL21,PDAP1,TMX3,CDCA8,ARF1,SLC12A9,TUBGCP2,DNAJB9,HOMER1,POLR1B,RNF5,RBM15B,PPAN,RHOA,RPRD1A,BTAF1,TOP3A,ARHGEF12,PCGF1,DDX23,RAB18,CACNB1,TRIM26,PDCD6,ATP6V1D,L3MBTL3,FAM110A,NEIL3,CTBS,BBX,IMPDH1,TAF12,NR2F2,PGAM1,HIPK3,IFI16,TXN,NUP188,H2AFZ,PNISR,PRKCSH,USP39,UBE2I,PARK7,SLC25A37,ZNF428,RAB4A,TRA2B,SUCLG2,TAF5L,SMARCE1,ZNF800,CDC5L,ZNF524,SGCE,OSBP2,NSUN2,USP22,CLNS1A,EIF3A,ZMYM3,DOT1L,IWS1,ANKRD10,WAS,KIF18B,TPP2,C1orf109,ZMAT3,B4GALT2,PRPF38B,RECQL,C9orf78,EWSR1,GADD45G,RRM1,ACAP1,B4GALT1,CYCS,SUPT7L,TMEM165,NPLOC4,CNOT3,WDR48,SPAG5,RTKN,CEP104,EXOSC7,KLHL5,LRRC8D,PPP4R1,MSH2,PIGG,FBXL7,OSTF1,MRPL40,SYTL3,FAM171A1,APOL1,EIF5A,GCC2,PRIM2,ELL2,RDH10,MFNG,RPS24,GORASP2,CAPZA2,ADRB2,CCT8,MTR,PHF6,PFDN5,SLCO4A1,TTC13,GOLGA2,RBMX,MED15,PIAS2,APPL2,SAMD8,NUDT3,CDKN2A,ZNF511,ATXN3,RAF1,KIAA0232,C2orf49,EPM2A,CD320,CCNA2,MTMR4,BRI3,TP53BP2,AQR,RBM12B,ILKAP,CDK12,SAP30,BRD4,DRAP1,NARF,LRRC8A,ELP4,ABHD11,PKMYT1,ASB13,SERP1,TRIM28,SUPT16H,EIF3K,CHMP4A,CBWD1,ATF6,XRCC4,PRPF4B,ADAM23,NDUFS1,DEPDC1,MECP2,SECISBP2,HMG20A,WWP2,JAKMIP1,SLC25A36,DNAJC8,AXIN2,CITED2,JMJD4,ANKRD37,KAT2A,TMEM126B,RABIF,ADSL,PACS1,BMS1,KCNQ1,OTUD3,ARSK,MACF1,KIF11,KLF6,COMMD4,SMAP2,FADD,SH3GLB1,MYO1F,CBX3,TMEM127,INF2,PPP1R11,DUSP11,DDX5,WDR62,TAF6,ESPL1,PURA,DDB1,DEF6,IPO4,FAM83G,UBL3,NAT9,PIGM,LYRM4,GPR132,UBE2Q1,PTP4A3,BRIX1,MRPL19,ZNF696,SF3B2,PCYOX1L,CDC42,SYNM,GOT2,JAZF1,HADHB,RPF2,SLC35C2,CNNM3,CARM1,SRPK2,WDR41,LARS,ZCCHC10,CCDC138,LRBA,TMEM216,SUMF2,KMT2C,OGFR,PRPSAP1,ASF1B,RPL37,MAN2A2,EIF4ENIF1,NIP7,U2SURP,MIA2,ZNF268,VPS4A,ATP6V0E1,PPP1R2,XPNPEP3,RGS2,LYAR,FAM89B,POLR2I,TRAFD1,SUGP2,GBA,EIF2A,SYVN1,DAPK3,ARHGAP15,MASTL,UAP1,NFIL3,FN3KRP,YWHAZ,CTSA,TMEM14A,TOB1,TSEN15,ADNP2,TCF12,PRKAB1,MDH2,SMARCA4,ORC1,RRN3,UBXN2A,IARS,CD3EAP,KIF14,EXOSC1,CS,CLTB,DNAL4,CSTF1,POU2AF1,UBQLN4,NXT1,HPDL,PGGT1B,SELPLG,SMU1,ATXN1,GLO1,OGDH,BICD2,CADM1,EDEM2,HERPUD2,TOLLIP,FANCE,MBD3,PDHX,RPS9,ALKBH6,SURF4,DUS3L,ARNTL,ANP32E,FKBP5,TMEM101,CCDC125,ABCA1,PDCD2L,GCLM,RAE1,DCTN2,NUP54,CHIC2,PAWR,MXD4,DCUN1D4,PIP4K2A,XPR1,FERMT3,KIF5B,KLHL20,SEC24C,RRBP1,ARHGEF2,ANP32A,LDLRAD3,C12orf75,STAT3,MYO5A,NIPAL3,AMPD2,TXNL1,PHF20L1,DCAF6,FAM49B,TMEM39A,ATP2C1,RFFL,COG1,RCOR1,PRMT2,TFEB,LEMD2,UPF1,ELMO1,ZC3H7B,DTX4,ZMIZ1,TERF1,HRAS,CCDC93,FGFR1OP,TMED7,PIGQ,AGPAT1,CNTROB,PPP1R16B,MIS12,GSDMB,TTC9C,PDS5B,NUP153,SENP1,PGAP2,TMEM115,DCUN1D5,PLEKHF2,BRMS1,PWWP2B,TRIM47,WDR11,AXIN1,SMG9,TRIM52,LONP2,NDUFV2,PHF23,CERK,SLC4A2,EZH1,ITGB5,LMNA,MCTS1,DDX56,EIF2S2,SLC38A5,FOXN2,CARS2,PRRC2A,C16orf72,RB1CC1,ZMYND11,PGS1,MYBL2,UHRF1BP1,SRSF5,MPG,MATR3,CYB5A,NCDN,POLR2J,SETD3,CNOT6,NDE1,EGLN1,ZNF207,ANKRD27,ABCA3,SARNP,IVNS1ABP,RMI2,MON1B,TMEM97,NIT2,NUF2,ZNF267,TCF19,TMEM161B,KTN1,APP,PRKD3,CLUAP1,ATP2A2,UTP18,GRSF1,DUT,ZCCHC2,ANAPC7,RNF19A,FAM76B,CLN6,TMEM9,GCC1,RNF169,ADCY7,ATP6V1G1,ENPP4,RNPS1,CDCA2,FKBP3,GPR137,DDX17,CHCHD3,PEX5,CDC16,HIPK2,MBOAT1,TICAM1,PDXK,ZBTB11,ANXA6,TMBIM4,GMCL1,UBE4A,IL21R,ETS1,WRB,ZNF92,PNO1,CAPN2,ADD3,SUV39H2,TTLL12,TPCN1,TMX1,LYPLA2,HNRNPM,MFSD12,LDHB,PPP3CA,NUDT8,POLK,JTB,EMP3,MTMR12,ZP3,PDE3B,KIF18A,CCDC6,WNT5B,MAPK6,C4orf46,LY75,SLC25A19,RGL1,PSAP,WDR76,IGBP1,FAF1,COX15,THOC1,AGRN,GNPDA1,GPBP1L1,PPP1R15B,CSNK2A1,EBNA1BP2,GIT2,BIRC2,ATPAF1,DLG5,ABL2,XRCC2,ZFYVE27,MCMBP,PTPRK,CDC37,METTL1,SP3,EXOSC6,HARS,GMFB,ESYT1,ANLN,RAB5B,RHEB,DPYSL3,TBC1D17,TIMM13,CDCA4,TONSL,NRM,NAGLU,ACTB,ZNF45,TMUB1,CTCF,ASAH1,DOCK11,CRLF3,ASXL2,LRRC14,NUS1,SLC27A4,AFF1,MDFIC,MAML1,CYTH1,NQO2,UTP15,EIF2AK1,EIF4G2,ZDHHC3,MOSPD3,ITPRIPL1,CDC27,SNAP23,TBPL1,PRMT7,KCTD7,NDUFA5,CYLD,UGP2,DYNLL1,COPE,HCFC1R1,ZADH2,GGPS1,RPAIN,RAD23A,PDK2,ATP6V0B,STRBP,DUS4L,MRPL34,PDCD2,SAP30L,SLC39A9,CLPTM1,RPL29,RPL35,BTG2,DNAJC9,MTMR6,FRAT2,NFATC2,KDM1B,ARL5B,USP36,MRPL2,ATP1A1,CLK3,PSMD3,MAFK,CEP55,NDUFA11,DNAJC17,ZNF436,NCOA1,SLC25A39,ZC3HC1,ZNF146,ATXN7L2,CDC40,GOLIM4,SMAP1,RRP15,DAP,GNE,SMC6,ARFIP2,NKRF,CHAC2,BZW2,WRNIP1,SS18L1,CENPM,PTGES3,CAMK2G,MLEC,ZNF202,PPWD1,FAM50B,RHOT2,NEU1,TPD52L2,GOLGA7,TWSG1,PGRMC1,GLG1,FAM126A,RPS6KC1,UBE2C,PPCS,NDUFB6,TMEM41B,ZDHHC8,PLXNA1,CCNB1,SLC20A1,COMMD6,ABHD14A,POLR3K,C14orf119,ASAP2,SNUPN,CNPY4,TFG,PLCL2,SEH1L,ATG9A,PBK,MKI67,DDX20,AMDHD2,GALNT7,SLC17A5,CCNF,FOXRED1,RBM47,PTER,WDR4,DHTKD1,TRAF5,HDAC2,PWWP2A,HSPH1,LIME1,MAPRE1,CHTF18,KIF23,SLC35B1,NOTCH2,PMF1,JMY,FKBP1A,SLC31A1,SNX18,ATIC,CTPS1,ATP6V0A2,PIKFYVE,RNF135,LPCAT1,EEF1D,TMED2,FTL,PHF10,DDX28,ZNF84,SIGMAR1,PIP4K2C,FAM133B,RIT1,PLEC,KDM3A,SF3A2,FAS,EPRS,ZNF777,TMEM54,QARS,PPP3R1,TCOF1,NRBP1,CABLES1,DNMT3A,RWDD1,CKLF,TRIP10,SF3B1,RPS6KA1,CAST,SUZ12,RAC1,GPR89A,OLA1,SNN,GNB2,FLAD1,APLP2,KDM2A,TNPO2,CDKN1B,TALDO1,GPX4,ATP13A1,RFC3,MAPRE2,ERF,CUL3,SLBP,KIAA1586,H2AFV,POLG2,GAR1,PSMB9,DHX57,NSA2,HSPA4,MRPL55,JAK1,TBL3,SEL1L,H2AFX,KLHDC4,B4GALT3,PDCD11,ATMIN,POLQ,POU3F2,OTUD5,NCOR2,ANKRD13D,PKP4,SCAMP3,CDCA3,SLC25A12,BLM,TMCC3,GTF2F1,CRAT,AHSA1,PRC1,UPF2,COPS7B,SLC38A10,CNOT6L,CNPY3,UBE2M,IFT46,TMEM160,TSHZ1,ZFP64,DENND4C,DENND1B,WDR18,RPL8,ILF3,LRRC1,RHOT1,TSR2,MARK2,ECH1,PRDX1,PLD3,NUCB1,FBXO21,GNA12,C1orf131,PRDX3,PFDN4,HNRNPH3,STX18,TFDP1,KHSRP,ASNA1,CPEB2,SSSCA1,BYSL,VPS29,S100PBP,MIB2,IER2,PTMS,NOP2,UBN1,DCAF15,NF1,FLYWCH2,ALKBH5,MOGS,TAF6L,MAPK14,BECN1,SNAPC4,RNF103,BCAT2,MBD4,C18orf32,METTL14,ZNHIT6,IMPAD1,RCSD1,PHTF1,SRI,KIF22,ZBTB22,NFU1,OGG1,TRIM14,ELOF1,COPS8,FYTTD1,TRIM8,RRM2,SOX4,ABHD5,CXXC4,UBTF,PAF1,UEVLD,SPATA2,PQBP1,IARS2,ATXN2L,GALNT10,STARD3NL,RPS15,PIGN,AGTRAP,CIB1,XPO7,SRRT,ZNF449,CAPZA1,GLTP,BCL2,KIFAP3,N4BP2,HP1BP3,THNSL1,ISG15,CAND1,GNAS,TSC1,RBM25,CDCA5,ZFP90,NANP,RBBP4,ZBTB24,SMARCD1,MBD1,WASF2,MMACHC,TOMM20,IFI27L1,GNPNAT1,HNRNPUL2,CHD1,MEAF6,C2orf68,CCDC50,AKAP8,PARL,RPN2,CHTOP,FAM3A,F2R,TMEM14C,SCYL3,ABI1,HTRA2,MOSPD1,RLIM,FAM172A,ZNF500,PSMB7,NLN,WIPF1,BOLA1,BUD13,NDUFB1,PEF1,BTBD1,TAB2,CHCHD1,TULP3,WDR59,CANT1,SCARB1,GAS2,USP11,SMURF1,TSPAN5,PPP2R2D,CDS2,MAGEH1,MRPL42,EYA1,CDK2AP2,MRPS26,LETMD1,KLF13,HDDC2,RGS1,MAN1A1,FBXO5,GART,PELO,TANK,BRD7,MRPL11,SAMD4B,ZDHHC18,POLR3GL,WDR81,MEN1,ZNF407,MFN2,COX8A,ZRANB2,MBD6,SRSF3,ATP6V1C1,IDH3B,TATDN1,TSC2,LACTB2,CMTM6,RBM4,ANKRD39,RPL23A,CDKN2C,USF1,DNAAF2,MECR,AP1M1,UPRT,CRY2,ECD,RNF26,TIPARP,LRRC59,ANKRD9,RHBDD2,MGAT5,ZNF559,RHOBTB3,GABPA,WBP1,NUTF2,ARF4,GINS4,KRIT1,BOLA3,AHNAK,RAD18,PDRG1,RNASEL,CHPF2,OAZ1,PDCD4,SMNDC1,NXT2,HIVEP3,KIAA0100,CLSPN,RHOC,DHX9,PDCD7,PSMD9,HAUS2,COPB2,TFAP4,CD59,RNFT1,RIMS3,MEGF8,EFTUD2,FBXO7,CPSF4,MRPL21,PHKG2,LUC7L2,SRSF11,EIF3L,MTA2,TYW1,USP10,ITM2A,SSR2,BCLAF1,MTX1,SFXN5,FNTA,PDLIM1,TXNDC16,ZNF830,MRPL3,ALS2,TRIM41,KARS,NQO1,POC1A,ANK3,PTTG1,TPX2,TBC1D13,DAZAP2,STMN1,GLRX3,C19orf48,REPS1,CBWD5,ABHD16A,FBXL6,SH3BP1,MTA1,UBA5,CLCN6,RPRD1B,SZRD1,CGGBP1,CPNE1,SEC61B,POLR2L,FAM118B,GOPC,E2F3,CIRBP,RPL38,CRNKL1,PFKFB3,GORAB,RAB1A,GIGYF1,TMEM184C,PPP2CA,KIF2A,CCDC14,LSM6,RNF38,SNRPG,DMWD,USP13,ZFP91,IP6K2,WDR5,SLC25A43,IFT27,PMVK,NEIL2,RRP36,SRXN1,RPA2,PSMD2,CLIC4,PDCD10,CBWD2,COQ4,ITGB8,ARF5,ARHGEF1,FBXL19,TTPAL,UTP20,MAGT1,GPS2,DBI,SSNA1,MRFAP1L1,CD81,TMEM131,WDR13,FANCI,PAPOLA,CREM,TET3,FANCL,GLIS2,IL6ST,INTS1,POP7,SLC44A1,MTPN,ASB6,PLK1,RPP25,SEPT9,CELSR2,RBX1,APH1A,RAD51AP1,ZBED5,CKAP2L,PSMG1,UBE2V1,EAF2,IL12RB1,KRTCAP2,LUC7L,LSG1,NECAP2,C1orf122,ALG3,TRIM4,AGPAT2,CHD3,ZNF367,E2F4,PRPF4,KPNA2,BEND6,CLN3,DNAJC30,FAM208A,NGLY1,POT1,MYL12B,CCDC137,RMND5A,HJURP,DNAJB2,FAM53C,NKD2,SDC2,KLC1,CDK13,ADCK5,COX4I1,DNAJB1,RAB6A,ARID1B,C1GALT1,MLX,UBE2Q2,CCP110,ZNF746,ARL6IP1,CTR9,NIPSNAP1,ABHD2,DCAF8,ACSL3,LDB1,MAP4K3,ARMC8,RBM38,NMT2,IRF5,RPL36,HAUS8,MBIP,ORMDL2,COX7A2L,ZDHHC7,SIL1,FAM122A,DTD1,UNC13C,BCCIP,SART1,TRAF7,TOR1AIP1,ZNF416,LAGE3,TM9SF3,ZFYVE21,RRAGC,ZNF121,OIP5,NRF1,WDR44,PPME1,PIN1,EFCAB11,RPAP1,CABLES2,LMAN1,AHCYL1,TOP1MT,STRAP,SPSB3,ZNF583,SNX25,ARHGAP17,POLR2G,ZNF780B,KIAA0040,PPT1,NUP155,DCLRE1C,MRPS14,RHBDF2,SUGP1,RBL1,FASTK,UBXN2B,STK38,AP1S1,SPRYD4,H3F3A,CHID1,SMAD4,RAD51D,SLC30A9,CMAS,UNK,NADSYN1,HMGN3,NCAPG,SCYL2,FZD6,HERC3,GTPBP3,CTSS,ORC3,RNLS,YTHDC1,ACP2,HMGN5,CSRP1,METTL5,ABCF2,TUFM,RANGAP1,PNPLA8,HAGH,API5,ZFR,SEC23IP,E2F1,TMEM219,USP20,RBPJ,PDCD6IP,MAX,LUZP1,GXYLT1,ADAM10,CXXC1,TSC22D3,AP3M2,CUL1,GYG1,NANS,OAT,MYEF2,ANKRD26,PA2G4,NOL11,FIZ1,ZNF200,SLC26A2,SRP72,KLF10,LACTB,CBFB,RFC2,RAB2B,MAP3K4,HHEX,LUC7L3,RPS14,MAP4,MRPL27,BTF3,PTPDC1,NMD3,CCDC59,PTOV1,COX5B,DNAJC5,SCOC,DHPS,POLR2K,ANKH,VAV2,PRKAA1,C16orf87,GSPT2,TATDN3,DLGAP4,PXMP2,PSEN1,ZNF79,PDXDC1,VPS25,NDUFS7,YY1AP1,C12orf10,FAM192A,RPN1,LHX8,ARPC5,ZNRF2,TPST1,DAPK1,PIK3IP1,CYC1,SOCS5,FDFT1,PIGT,EMB,WDR1,ZNF574,C1orf35,EXOSC9,ARID1A,PTTG1IP,C9orf40,FXR1,GOSR1,MAP2K2,TWISTNB,AKAP1,XRCC5,HMGN2,PI4K2A,SEC31A,CAT,DERL1,HSPBP1,MTHFD2,CEBPG,ARAP1,USP32,FAM83D,CABIN1,SMPD4,GPI,CYTIP,TP53RK,REPS2,RAB11B,UROD,SLC39A13,POMP,BCL2L1,DECR1,RALB,SIAH1,ADCY9,LPIN2,SOCS6,MRPS27,TTC3,RNASEH2A,CFL1,ANKLE2,CDC123,OAF,VDAC2,EDF1,ERC1,EML4,AMZ2,ANKZF1,ZNF282,RAD51C,DSN1,DDOST,HINT1,DGCR8,SAFB,HAGHL,RWDD4,FTSJ1,LMBR1,NCLN,BEND3,EYA2,DYNC1LI2,SLC41A1,B4GALT5,MANBA,TKT,FAM76A,CBLL1,ARGLU1,LANCL1,POFUT1,FAM8A1,HEATR5B,HLA-A,EBP,RFWD3,NDUFA2,FUT8,FJX1,BTF3L4,PTPN11,MRPL54,FEM1B,RPL19,CNN2,NDUFA3,MTX2,MSH6,PDLIM2,LONRF3,RFXANK,FBXO9,GUF1,RPL32,ZHX1,NDUFS5,WDR91,HIGD2A,ZBED3,RORB,POLA2,ZNF76,COPA,HMGXB3,PHRF1,ABCB10,COMMD5,MAP1LC3B,DST,SIVA1,RAB35,GPATCH1,TCEA1,DRAM2,DEAF1,TRAPPC13,SNRNP200,NCK1,LAP3,VHL,SREK1,ARHGDIB,PITPNB,HSPB11,BRWD1,PPM1G,SH3GLB2,CRCP,BAZ1B,CAB39,ACBD4,STK11,CLU,CHEK2,ZSWIM3,TSTD2,MRPL13,CHPT1,DCAF5,CAPN1,UBE2D3,NSMCE4A,PPP1R12A,ZCCHC8,GORASP1,NACA,UBXN1,EPN1,PCSK7,RPL15,THRAP3,TTF1,QSOX2,PRPF18,NUP205,CHKA,DTL,MED10,ZRANB1,MCPH1,SLC12A2,ATP6V0D1,CSNK1G3,CREG1,NUDT4,RPL6,VKORC1,SLTM,EVC2,KLHL15,SIAH2,SLC16A1,EHD4,SNRNP70,C11orf1,APOL2,N4BP2L2,SNX27,CHMP2A,CORO7,FEZ2,PMS2,UCK2,UCK1,CLCC1,EXT2,MXD1,USP5,HNRNPA2B1,SAP130,NVL,PPP6C,CYB5R1,ZNF770,EBAG9,RNF25,PCGF6,METTL2A,PON2,STAT6,HPS5,MAPK1,BRD9,TMEM33,NAT14,DNAJC2,TRIP12,SHPRH,SCYL1,VPS45,MYO9B,GFM2,SPPL2A,FASTKD3,FGFR3,PPIG,ZDHHC13,TMEM99,H2AFY,ATG13,NDUFS8,ERI3,FBL,SLC35A1,FRMD8,MICAL3,TGFB1,B3GALT6,ELOVL5,HEMK1,TIMMDC1,HELB,PSPC1,MIER1,SCFD2,NDRG3,CDK11A,MTMR3,ACAT1,CENPT,PLOD3,RAB3IL1,ZSWIM6,RAB14,ADD1,MRPS15,KDM4A,XIAP,DHX8,GLUD1,ANKRD23,PABPC4,CALM2,CDK5,PSMD1,NEK6,NSRP1,RABGAP1L,SRSF4,FNIP2,KCNAB2,PCBP2,MLST8,PLK3,ZNF672,MRPL43,HSDL1,TOPORS,MCL1,SMC2,PPFIA3,ICMT,STOML2,LIMK1,ZNF689,PRDX5,ATE1,MLYCD,ATP6V0C,ST3GAL2,FBXL3,TFDP2,E2F2,PFKP,AAAS,DDX42,SSRP1,MRPL9,MRPS2,STRN4,TOP2B,ZNRF3,TMED3,DDRGK1,RAVER2,GNS,INTS7,INPP5A,MCM5,PHF14,ZNF326,NAGPA,TIMM8B,ETV3,DHX29,TEX10,MAN1B1,RPS10,CBFA2T2,ABCF1,RHOB,LRRC14B,DTWD1,PTPRF,SCARB2,OSBPL11,CCDC86,DUSP3,SLAIN1,MDH1,HEXA,RNF139,SNX14,ZNF296,TRERF1,UBR2,CHD1L,ACTR3,WDTC1,MYH9,CREBL2,NIPA2,PRKACA,SAFB2,ANKIB1,STAM,ARL6IP6,RAB21,SP100,ZKSCAN1,DDA1,NUP107,ANKRD13C,MAVS,CEP63,TMEM136,RBM15,ATF2,DCTN1,SHOC2,PSRC1,MAP4K4,WBP2,ATP6V0A1,NDUFA7,DNAJA1,TAZ,TAF2,SEC61A1,WDR7,RPLP1,CBLN2,RBMS1,FUS,GEN1,LRP8,COIL,LRCH1,GALK1,ZNF786,RPS2,SESTD1,TRAK1,JMJD6,SIKE1,AKT1S1,KRI1,FBXO3,ERH,PPP1R8,PRDM4,GTSE1,GEMIN6,DCP1A,SGCB,S100A6,IMPA2,NUDC,PDPK1,TK1,GUK1,TNFAIP3,GALC,ZNF512,KIAA0930,MRPS10,DDX39A,RPA1,ZNF862,ZNF180,KEAP1,POLE,TATDN2,PITX1,CAPN7,LRPPRC,PML,HMGB2,USF2,ANAPC4,SRM,DDX47,MCCC1,CDC42SE2,S1PR2,CDIPT,SEC16A,SSR1,LIN9,PCNA,ZNF639,PIK3R2,ETV6,TXLNA,PPCDC,FAM86C1,MYBL1,MRPL32,CCAR1,ABCC5,PBXIP1,BAZ2A,TLK1,MRPL12,EZR,LNX2,LRP5,BRCA1,PRKRA,STX16,EPB41,OPTN,SOCS4,QRSL1,PIEZO1,GLCCI1,NUDT11,NAA60,GEMIN7,SEPHS2,LZTR1,RACGAP1,PPP3CB,B4GALT4,RLF,RAPGEF6,SNRNP25,RB1,VASP,MED8,VMP1,PPIL2,MEA1,TIMELESS,AHDC1,ALDH18A1,TMEM8A,ABCC1,PREB,TRAPPC9,AACS,MEMO1,KRAS,RTF1,UBE4B,NFATC2IP,LY6E,ARPC1A,ZNF174,PSMC4,GOLGA4,SYNCRIP,PALB2,PRPS2,NIPA1,TIGD2,RNF114,FOXM1,MRPL39,XAB2,SUMO2,DUSP22,COMMD8,RPL11,CSDE1,MDM2,CORO1A,MINPP1,METTL9,POC5,DVL2,GM2A,PSMA8,COQ10B,CPOX,TIGD5,SLC26A6,CYP20A1,PRPF3,TXNL4A,RPSA,SRSF1,DNAJC10,ZNF700,SCAP,PLEKHG4B,TIMM17A,FAU,LTA4H,AP2S1,USP53,INTS2,CTDP1,MIF4GD,CDT1,ARID5A,SUMF1,GGA2,AP3S1,CSNK1A1,RMI1,TFRC,PTPN2,IRF4,GSTK1,NDUFV1,SLC1A4,CWC27,SLC35B4,DDX31,ABCD1,RPAP3,CNTN5,SNX2,ZMYM5,CCDC34,CHCHD6,BSDC1,KPNA4,FBXO41,BIRC5,TFE3,SNAP29,CDCA7L,PKD2,ACADM,CHMP7,SAT2,GCSH,ZNF496,TMEM109,TAP1,NHLRC3,IKBIP,EIF1B,ELMOD2,KIFC1,DBNDD1,CYB5RL,PARPBP,RNASEK,CDC25B,PRADC1,DNMT1,NOL12,ORAI2,USO1,AKT2,NOL8,GNG7,AURKB,MCFD2,SLC25A5,ZFAND5,MAK16,STT3A,TMED10,EIF2D,ITGB1,PTPN7,UQCRH,RRS1,ARRB2,RTN3,ZNF598,SVIP,DDX58,WSB2,PPIB,MUT,GMFG,HLA-E,NDUFA4,MAN2B1,METTL3,CFLAR,NDUFS4,RNF121,MEX3C,KLF16,HDAC7,DAD1,BDH1,GNAI2,ANKHD1,MORC3,TERF2,KCTD20,SEPT8,DCTD,PKM,TOMM40,PATL1,ADSS,SERTAD2,SERF2,ZFP92,NSF,DCK,ERGIC3,ACLY,LPCAT4,VCPIP1,YY1,PPP6R2,MAP3K5,PPP6R3,RNF14,CDK2,ZC3HAV1,SYS1,ZBTB37,URB2,EIF3D,MAGED1,KLHL18,ADPGK,SLC25A44,AP1B1,SDHA,PAIP2,PHC2,CRKL,MOAP1,TERF2IP,CYHR1,ZNF75D,SHC1,UCHL5,NAA35,TMBIM1,CCT2,CDKN2AIP,MKLN1,HMGN4,GALK2,CDC23,SHCBP1,AP4E1,PRDM11,VEZF1,PPP2R5A,ACYP1,STAT1,PPA2,TRIM32,RHEBL1,C1orf112,MRI1,TCF3,BRAP,AGPAT3,MYNN,SDF2L1,SPR,RAB11A,REEP5,FOXO3,MAD2L2,CCDC28A,PIP5K1C,RBM17,MAT2B,PTEN,CENPJ,TAGLN2,OSTC,CREB1,PACS2,NCOA2,SMC4,RNASEH2C,NEK7,NET1,PARP4,TBRG4,ANAPC2,RPL27A,YIF1A,SGSH,HGS,TTLL4,SLC38A7,MFAP1,CCDC69,BRWD3,ESYT2,SKA3,NPHP4,UBE2E2,HNRNPAB,PLXNC1,ST13,TMEM184B,DNAJC24,ZNF107,SLC29A1,KIF2C,AGFG1,SIRT2,FKBP2,USP48,UBQLN2,SNRPD3,CUTC,EDC3,UBLCP1,ZNF804A,RAP1A,THADA,EIF4A3,AP3S2,ATG3,DPYSL2,PPP1R12C,AKR1B1,NDUFB9,JOSD1,RP2,TTC4,TECR,ARID4A,FGFR1OP2,TIMM50,TDP1,DPM1,FOPNL,SLC16A7,WDR82,SLC25A22,STK17B,DHX15,CHAF1A,GEMIN5,COPS6,SASS6,RPS26,PSMC1,SLC12A7,TBC1D12,TM9SF4,ZNF768,MED13L,TIA1,MEF2A,EPHX2,PITHD1,RHBDD1,NFATC3,BANF1,BUD31,ZNF335,YBX1,KNTC1,ACAD8,UBE3C,ZNF189,ALDH9A1,KDELR1,TSTA3,CIC,OXR1,PSMA1,SEPT7,NAP1L1,NSMF,ODF2,EXOC4,KIAA1328,NUP62,PITPNA,NAA20,PTDSS1,MZT2B,PDSS2,C7orf26,TMEM106C,IMMT,ASH1L,CHERP,WDYHV1,PLAGL2,CHKB,IRF3,TWF2,PAIP1,ANKRD28,ANKLE1,FARSA,SAR1A,SCAMP4,APOOL,PDIA6,ACSL5,AZI2,GFER,RAD54B,DAP3,TMEM41A,ZNF317,GADD45B,AKNA,REEP4,CBX4,MIF,KIF3B,GOLPH3L,SH2D3A,CASP6,TOR3A,SRGN,DBF4,MFSD10,SAC3D1,CTNNBL1,YIF1B,CLDND1,TTC17,SLC25A1,GINS1,PAQR6,CSNK1G2,TELO2,ADAM17,HMGN1,NASP,ASPM,PPP1R21,PRKAR1B,SYMPK,TARS,SNRPA,MAPK3,HSPA1B,HLA-B,ATAD2,PLAA,ZNF330,OSBPL8,KBTBD7,PREPL |
| 1.839e-06 | -13.21 | RRM_dom | interpro domains | IPR000504 | 216 | 59 | 18492 | 2768 |
NIFK,EWSR1,HNRNPAB,SRSF6,RBM8A,TIA1,SAFB2,MYEF2,RBM4,PABPC4,RAVER2,HNRNPA2B1,RBM17,RBM23,RBM34,GRSF1,SRSF4,TRA2B,TARDBP,RBM3,RBM12B,RBM15,PABPC1,HNRNPM,SRSF10,RBM15B,SRSF11,RBM42,PSPC1,NOL8,SF3B6,PPIE,HNRNPF,RNPS1,CIRBP,SREK1,SRSF5,EIF4H,EIF3G,SLTM,MATR3,SNRPA,RBM38,SRSF1,RBM25,RBM47,SYNCRIP,HNRNPR,HNRNPH3,SAFB,RBMX,U2SURP,DNAJC17,RBMS1,SRSF3,FUS,SNRNP70,HNRNPDL,CPEB2 |
| 1.851e-06 | -13.20 | GOLDRATH_EFF_VS_MEMORY_CD8_TCELL_UP | MSigDB lists | GOLDRATH_EFF_VS_MEMORY_CD8_TCELL_UP | 195 | 55 | 17377 | 2626 |
TXN,H2AFZ,MCM10,SUZ12,VPS45,UCK2,CDCA3,TMEM97,RRM1,CDCA8,KIF23,KIF2C,STMN1,TCF19,LYN,DTL,CDKN2C,IRF4,CCNA2,UCHL5,SIVA1,PRC1,KIF22,TAGLN2,TMEM14C,TACC3,FDFT1,TK1,ASPM,NUDT4,RAD51AP1,MKI67,EMP3,RRM2,NUSAP1,CDC6,AURKB,BRCA1,SMC2,ANLN,CCNF,KIF11,ASF1B,CHAF1A,PRIM1,BIRC5,RBL1,DCK,MAPK6,DBI,H2AFX,NUP62,KPNA2,FKBP5,CCNB2 |
| 1.861e-06 | -13.19 | pancreas-carcinoid-endocrine_tumour-glucagonoma | COSMIC cancer mutations | pancreas-carcinoid-endocrine_tumour-glucagonoma | 9 | 8 | 17385 | 2587 |
GNAS,CDKN2C,NRAS,PTEN,KRAS,MEN1,SMAD4,HRAS |
| 1.861e-06 | -13.19 | glucagonoma | COSMIC cancer mutations | glucagonoma | 9 | 8 | 17385 | 2587 |
GNAS,CDKN2C,NRAS,PTEN,KRAS,MEN1,SMAD4,HRAS |
| 1.864e-06 | -13.19 | adenyl nucleotide binding | molecular function | GO:0030554 | 1514 | 297 | 17224 | 2647 |
ABCC10,TAP1,DHX8,GLUD1,UBE2I,EEF2K,KIFC1,CDK5,NEK6,ATP13A3,PDS5B,SUCLG2,MAST2,PLK3,RHOBTB3,AKT2,PBK,KIF15,MKI67,DDX20,SMC2,AURKB,MCM2,RFC2,MAP3K4,MKNK1,KIF18B,LIMK1,MYO18A,RNASEL,LONP2,PFKP,DDX42,DDX58,HSPH1,RECQL,CHTF18,TRIO,PRKAA1,DHX9,RRM1,CERK,KIF23,TOP2B,EIF2AK4,DDX56,SMC3,MCM5,CTPS1,MSH2,DAPK1,RTCB,PIKFYVE,PHKG2,UBE2QL1,CARS2,DDX28,COQ8A,MAPKAPK3,DHX29,PGS1,PIP4K2C,PKM,ABCF1,MAP2K2,CCT8,PI4K2A,XRCC5,EPRS,HSPBP1,NSF,CSK,CSNK1G1,DCK,QARS,ACLY,MAP3K5,CDK2,NRBP1,ACSF2,KARS,ABCA3,TP53RK,RPS6KA1,RAF1,CHD1L,KIAA0232,ACTR3,OLA1,TPX2,MYH9,PRKACA,CBWD5,FLAD1,PRKD3,ATP2A2,UBA5,ADCY9,CLCN6,TAP2,AQR,CDK12,ADCY7,CCT2,ULK3,ATP13A1,TAOK1,MAP4K4,PFKFB3,GALK2,PKMYT1,DNAJA1,MAT2A,DHX57,DDX17,KIF2A,RAD51C,HSPA4,JAK1,HIPK2,CBWD1,PDXK,PPP5C,CSNK1D,DYNC1LI2,POLQ,PRPF4B,GALK1,TWNK,IP6K2,ATP5F1B,BLM,PMVK,PIP5K1C,SRXN1,CBWD2,GATC,TTLL12,MAP3K14,UBE2M,MSH6,SMC4,PDPK1,TK1,GUK1,DDX24,NEK7,BMS1,DDX39A,KIF11,MARK2,MYO1F,KIF18A,TTLL4,MAPK6,ASNA1,DDX5,DDX52,DDX47,UBE2E2,ST13,YTHDC2,MCCC1,UBE2Q1,UBE2Z,CSNK2A1,ABCB10,KIF2C,MAPK14,PAPOLA,ABL2,EIF4A3,TRMU,XRCC2,KIF22,ABCC5,SRPK2,PLK1,LARS,SNRNP200,HARS,TLK1,CDC6,STK17B,DHX15,CHD3,IARS2,BAZ1B,QRSL1,ACTB,STK11,CHEK2,VPS4A,ROCK1,PSMC1,SEPHS2,UBE2D3,CDK13,THRAP3,CHKA,UBE2Q2,KIF13B,AHCY,ALDH18A1,N4BP2,CSNK1G3,ABCC1,NTPCR,AACS,ACSL3,MAP4K3,EIF2AK1,UBE4B,BBS12,DAPK3,MASTL,PSMC4,PRPS2,NLRC5,SIL1,ATP5F1A,RUVBL2,MYO9A,EHD4,UCK2,PMS2,UCK1,SMARCA4,ORC1,CHKB,ATP6V1B2,TWF2,LYN,CHD1,MIEF1,FARSA,PDK2,IARS,NVL,KIF14,SCYL3,ACSL5,CLCN3,CGAS,RAD54B,ATP1A1,IDE,CLK3,DHX16,STK38,FASTK,XRCC3,MAPK1,ABCA1,RAD51D,KIF3B,NADSYN1,SHPRH,TOR3A,GNE,SCYL1,SMC6,MYO9B,CDK11B,CSNK1A1,SCYL2,PIP4K2A,WRNIP1,KIF5B,STARD9,FGFR3,GART,GRK2,ABCD1,DDX31,MYO5A,CAMK2G,CSNK1G2,HELB,PRKDC,BTAF1,ABCF2,ATP2C1,PRKAR1B,NADK2,PNPLA8,CDK11A,TARS,DDX23,HSPA1B,MAPK3,NEK1,UPF1,ATAD2,UBE2C,RPS6KC1,HIPK3 |
| 1.875e-06 | -13.19 | purine ribonucleoside triphosphate metabolic process | biological process | GO:0009205 | 218 | 60 | 17256 | 2622 |
GALK1,COX15,COX5B,NDUFA5,NDUFV2,NDUFS1,NDUFB6,UQCR10,MECP2,RAB23,OLA1,NDUFA4,COX4I1,CYCS,EFL1,ADPGK,ATP5F1B,ATP6V1B2,ATP5PF,SDHA,NDUFS7,NDUFS4,NDUFV1,NDUFA2,NDUFB4,MSH2,ATP6V0A2,NDUFB9,NDUFS8,CYC1,NDUFA3,TGFB1,RHOA,GUK1,LDHA,ATP6V0A1,OGDH,NDUFA7,NDUFB1,PKM,ATP5MF,TAZ,STOML2,HSPA1B,MBIP,ATP5MC3,PARG,COX7A2L,NDUFA11,COX8A,IMPDH1,COX5A,DHTKD1,UQCRH,NDUFS5,GPI,ATP5F1A,NIPSNAP2,PGAM1,PFKP |
| 1.875e-06 | -13.19 | GO_MITOCHONDRIAL_TRANSLATION | MSigDB lists | GO_MITOCHONDRIAL_TRANSLATION | 104 | 35 | 17377 | 2626 |
MRPL9,MRPL42,MRPS2,MRPS15,MRPL39,MRPS26,GFM2,MRPL19,MRPL50,GATC,MRPL34,MRPS27,MRPL54,MRPL40,MRPL48,MRPL11,MRPL21,MRPL32,HARS,NOA1,TUFM,MRPL43,MRPL12,MRPS10,MRPL16,NDUFA7,MRPS14,MRPL2,DAP3,MRPL55,CHCHD1,MRPL27,QRSL1,MRPL13,MRPL3 |
| 1.884e-06 | -13.18 | PRKRA (protein activator of interferon induced protein kinase EIF2AK2) | protein interactions | 8575 | 63 | 26 | 17029 | 2761 |
STAU1,POLR2G,AGO2,GTPBP4,C1orf35,NKRF,EBNA1BP2,BRCA1,PRKRA,UBE2I,PRPSAP1,RPL36,CAND1,LYAR,RB1,SHC1,SYNCRIP,STRBP,DGCR8,RBM34,ZNF746,RBM3,TCOF1,COPS6,ZMAT3,IFI16 |
| 1.889e-06 | -13.18 | UBXN7 (UBX domain protein 7) | protein interactions | 26043 | 114 | 39 | 17029 | 2761 |
POU3F2,UBR2,UFC1,UBXN1,CUL1,ATP6V1B2,BIRC2,APP,NPLOC4,SRXN1,KIFC1,PSMD2,RAD23B,NSFL1C,TTLL12,CSNK1G3,USP34,CSTF1,ATG9A,RBX1,VHL,NSUN2,CUL3,UBE2V1,TOPORS,UBE4B,ABCF1,PHF6,WDR11,BRWD1,KBTBD7,VCPIP1,ZRANB2,BRWD3,UBE2C,SMURF1,FAF1,DDB1,SSSCA1 |
| 1.894e-06 | -13.18 | GO_NUCLEAR_ENVELOPE | MSigDB lists | GO_NUCLEAR_ENVELOPE | 391 | 94 | 17377 | 2626 |
CHMP2A,NUP188,MRPS15,TOR1AIP1,TMEM109,TMEM97,AGFG1,BCL2L1,UBE2I,APP,MRPL19,TERF2IP,DST,FANCL,SNUPN,AHCTF1,NUP210,INTS1,MTA1,NUP107,TNPO2,NUP153,FAM76B,RBM15,LRRC59,SENP1,SEH1L,NXT1,MTMR6,HTATIP2,TOR1AIP2,NUP155,NUTF2,MRPS14,TMEM201,CERS6,NRM,ATF6,KPNA2,CHMP4B,SMAD1,ZC3HC1,AAAS,TUBB,ANXA11,TMEM33,INTS2,DNAJC2,RAE1,CENPF,RRM1,NUP54,BRAP,AGPAT3,GMCL1,XPO7,PSEN1,QSOX2,NUP205,LMNA,DTL,NDUFB4,EI24,TNPO3,YBX1,BCL2,GLE1,MVP,TNRC18,NUP85,S100A6,EIF5A,SIGMAR1,RB1CC1,TEX10,GTPBP4,RANGAP1,ABCF1,MATR3,MAPK3,CBX3,LEMD2,KPNA4,PDCD6,PCM1,KPNA1,OSBPL8,PML,LRPPRC,AEN,NUP62,CHMP7,FAF1,IPO4 |
| 1.924e-06 | -13.16 | GSE17186_CD21LOW_VS_CD21HIGH_TRANSITIONAL_BCELL_CORD_BLOOD_DN | MSigDB lists | GSE17186_CD21LOW_VS_CD21HIGH_TRANSITIONAL_BCELL_CORD_BLOOD_DN | 181 | 52 | 17377 | 2626 |
TCF12,UBL3,NADSYN1,PPCS,ADD1,TCF3,SLC2A1,PMS2,CIB1,CERK,MYNN,ABHD14B,EZH1,MXD4,KTN1,TRIM65,CLUAP1,PDCD10,ADD3,HDAC7,RCSD1,CNPY4,GEMIN4,TECR,CNOT6L,PLCL2,GPD1L,SPTAN1,NCK1,ZNF512,LDB1,SLC16A7,EZR,ESYT1,ICAM2,RAB2B,NEU1,XRCC5,UBTF,HHEX,ZNF317,JAK1,CSK,PRPS2,ARNTL,SH3GLB2,PQBP1,SLAIN1,SNRPG,ZSWIM3,USP11,PDCD4 |
| 1.924e-06 | -13.16 | GSE3982_DC_VS_MAC_LPS_STIM_UP | MSigDB lists | GSE3982_DC_VS_MAC_LPS_STIM_UP | 181 | 52 | 17377 | 2626 |
NDUFV2,GNPDA1,ABCC10,GNE,LETMD1,SMARCA4,TBC1D13,FAM136A,SEC16A,RCOR3,EPM2A,WWP2,TERF2IP,IRF4,SHC1,SLC1A4,INTS7,NVL,MTMR4,GOT2,PPP1R8,GRSF1,MEA1,ZDHHC13,PDS5B,DDX31,TAF5L,CEP63,NAGPA,ZDHHC18,DDX24,HARS,SELPLG,DCAF8,PARP4,CIRBP,NUP155,CDC23,POLG2,TARS,MAT2A,ARHGAP15,CYB5A,AMZ2,MFAP1,STK38,OGT,CEBPG,CCDC69,BAZ1B,TRAF5,SMURF1 |
| 1.924e-06 | -13.16 | GSE21033_CTRL_VS_POLYIC_STIM_DC_3H_DN | MSigDB lists | GSE21033_CTRL_VS_POLYIC_STIM_DC_3H_DN | 181 | 52 | 17377 | 2626 |
SLC12A7,GGNBP2,TMEM184B,ADD1,KIAA0100,GORASP1,GGA1,SNAPC4,RMI1,STAM,REPS1,YY1AP1,SSR1,PCYOX1L,KRI1,CCNA2,AHSA1,SEC24C,MEA1,NUP107,PDS5B,EI24,FAM89B,NSFL1C,BRD7,ARHGEF2,KIFAP3,SLC38A10,SS18L1,PCYT2,ACAD8,MAML1,HTRA2,MSH6,ADCY7,AATF,NQO2,LRRC1,PPFIA3,CDC23,PRMT2,PRIM1,CBX3,MAP3K4,TSC1,TRIM26,AGPAT2,NEIL3,FN3KRP,PPP5C,NDE1,TOB1 |
| 1.935e-06 | -13.16 | GCM_CBFB | MSigDB lists | GCM_CBFB | 67 | 26 | 17377 | 2626 |
HMGN1,NASP,POLR2G,SUMO2,DHX9,PSMA1,SLBP,CTCF,SNRPD3,UBE2I,STMN1,PCBP1,CBFB,SNRPA,ERH,NAP1L1,PSMA6,DUT,CAPZA1,TRA2B,DDX5,YWHAZ,TCEA1,ACADM,RBBP4,HNRNPM |
| 1.935e-06 | -13.16 | UBE4B (ubiquitination factor E4B) | protein interactions | 10277 | 82 | 31 | 17029 | 2761 |
UBE2D3,PPIF,SARNP,ATXN3,TRIP12,FOXK1,CASP6,UBXN1,VAV2,NUSAP1,UBE2V1,UBE4B,NDUFA7,TMEM165,STAM,RAD23A,HGS,MDM2,NDUFA2,CDC27,RAD23B,TTC9C,ZRANB2,TTC4,AHCYL1,IGBP1,UBE2C,CDKN2A,SSSCA1,VPS29,USP34 |
| 1.954e-06 | -13.15 | DNA biosynthetic process | biological process | GO:0071897 | 121 | 39 | 17256 | 2622 |
POLA2,CENPF,RMI2,BLM,RMI1,MAD2L2,NEXMIF,NPLOC4,WRNIP1,TERF2IP,LIN9,DTL,RPA2,PCNA,XRCC2,PTGES3,TERF2,RFC3,TK1,PRIM2,POLK,RAD51AP1,TOP3A,USP10,BRCA1,RFC2,GAR1,POLG2,ISG15,RPA1,RAD51C,PALB2,POLE,RPS27A,XRCC3,TERF1,POT1,RAD51D,POLQ |
| 1.963e-06 | -13.14 | GO_MRNA_3_END_PROCESSING | MSigDB lists | GO_MRNA_3_END_PROCESSING | 71 | 27 | 17377 | 2626 |
SRSF11,CDC40,SARNP,THOC1,SRSF6,RBM8A,RNPS1,POLR2D,SLBP,SRSF5,DDX39A,SYMPK,APP,CDC73,SRSF1,PAPOLA,PAF1,ZNF473,EIF4A3,GRSF1,SRSF4,SRSF3,CHTOP,AHCYL1,ZC3H3,PABPC1,CSTF1 |
| 1.963e-06 | -13.14 | SHEPARD_BMYB_TARGETS | MSigDB lists | SHEPARD_BMYB_TARGETS | 71 | 27 | 17377 | 2626 |
POU3F2,PHF20L1,TK1,FOXM1,ASPM,CDCA3,MKI67,TPX2,KIF23,CDCA2,BMS1,NOTCH2,AURKB,CCNB1,ANLN,KIF11,FBXO5,DDX17,RTKN,MASTL,ATP1A1,BIRC5,KIF14,PRC1,GTSE1,NDE1,TACC3 |
| 1.976e-06 | -13.13 | Nuclear Pore Complex (NPC) Disassembly | REACTOME pathways | R-HSA-3301854 | 35 | 18 | 10287 | 1696 |
NDC1,NUP188,NEK7,RAE1,NUP54,NUP155,CCNB1,NUP205,NUP210,NEK6,NUP107,NUP62,NUP153,CCNB2,NUP85,NUP58,SEH1L,AAAS |
| 1.989e-06 | -13.13 | MRPL35 (mitochondrial ribosomal protein L35) | protein interactions | 51318 | 42 | 20 | 17029 | 2761 |
MRPL9,MRPL42,MRPL39,MRS2,MRPL12,MKI67,RACGAP1,LUC7L,APP,MRPL50,MRPL2,NAP1L1,MRPL55,MRPL27,MRPL34,MRPL40,MRPL48,NAP1L4,MRPL13,MRPL3 |
| 1.993e-06 | -13.13 | BUB1B (BUB1 mitotic checkpoint serine/threonine kinase B) | protein interactions | 701 | 86 | 32 | 17029 | 2761 |
HSPH1,UGP2,PRKCSH,RAE1,PTTG1,CERK,NUF2,PMF1,AP1B1,MIS12,MDM2,PSMA6,CCNA2,AP2B1,ANAPC7,CDC5L,PLK1,PLK3,CCT2,ANAPC2,AURKB,CDC23,COMMD4,MAP3K4,CDC16,CDC27,DSN1,PPP2R5A,UBE2C,HDAC2,TUBB,ANAPC4 |
| 2.021e-06 | -13.11 | GSE18893_CTRL_VS_TNF_TREATED_TCONV_2H_UP | MSigDB lists | GSE18893_CTRL_VS_TNF_TREATED_TCONV_2H_UP | 186 | 53 | 17377 | 2626 |
EXOC3,PLXNC1,UBN1,GNPDA1,ADAM10,ACTR3,MON1B,LAMTOR3,PTP4A3,CHAC2,POMP,DAZAP2,RUFY1,APH1B,RAB11A,COPG2,PAIP1,NPLOC4,C2orf68,TMEM179B,KIF5B,MLX,COQ4,GOT2,RINL,CENPJ,PPP6C,BRD7,SLC27A4,DDX31,PLCL2,NSUN4,KCNAB2,MORC3,GALC,TMEM216,EIF2AK1,PSMB9,ECH1,MYO1F,MOSPD3,HLA-B,TPD52L2,KPNA4,POLR2J,TFDP1,ST3GAL2,HMGB2,DMWD,ZNF830,NRBP1,DEF6,PDF |
| 2.021e-06 | -13.11 | GSE40655_FOXO1_KO_VS_WT_NTREG_UP | MSigDB lists | GSE40655_FOXO1_KO_VS_WT_NTREG_UP | 186 | 53 | 17377 | 2626 |
UBL3,UNK,PPP1R12A,KIAA0100,UBN1,ARID2,TOR1AIP1,CTCF,TOP2B,USP48,WDR5,RAPGEF6,SNAPC4,C2orf68,KRI1,ZKSCAN1,HUWE1,SEC24C,EXOSC1,H2AFY,CNOT6L,ZNF770,PHF20L1,PTPN18,ATP13A1,RBM42,FOXK1,ZMYND11,RPL38,WDR82,ARHGEF12,PACS1,PLEKHM3,AZI2,LY6E,AP4E1,TAZ,TARS,MAT2A,VEZF1,SGSH,PPP2R5A,TTLL4,CSK,CHD3,MFAP1,BBX,MLYCD,PPP6R3,CLN3,SNRNP70,ZNF146,PRPF4B |
| 2.021e-06 | -13.11 | GSE411_UNSTIM_VS_400MIN_IL6_STIM_SOCS3_KO_MACROPHAGE_DN | MSigDB lists | GSE411_UNSTIM_VS_400MIN_IL6_STIM_SOCS3_KO_MACROPHAGE_DN | 186 | 53 | 17377 | 2626 |
HIVEP3,FGFR1OP,IMMT,ZNF496,H2AFZ,RAF1,CENPF,KCTD17,TOP2B,NPLOC4,PAIP2,TERF2IP,LYAR,SMC3,SLC1A4,SUV39H2,TIMM23,DPYSL2,PRDM4,RAD23B,MRPL54,FAM76B,PRADC1,CITED2,SLC12A2,GPD1L,MSH6,ELOF1,MND1,RHOA,CSRP1,MIER1,ACSL3,PSMA1,EIF4H,PHF6,FAS,PPP2CA,RAD51C,MTHFD2,DSN1,DUSP3,ELMO1,PRDX5,C4orf46,NCOA1,DMWD,YY1,REEP4,BRWD3,LRP8,HIPK3,CDKN2A |
| 2.021e-06 | -13.11 | GSE17721_CTRL_VS_CPG_12H_BMDC_UP | MSigDB lists | GSE17721_CTRL_VS_CPG_12H_BMDC_UP | 186 | 53 | 17377 | 2626 |
LZTR1,GNPDA1,MANBA,RAC1,ANKH,CENPF,MRPS26,TM9SF3,NUF2,HAUS4,PARK7,CCDC28A,TFRC,XPR1,GOLM1,ATP6V0B,PCNA,CCNA2,DUT,IL6ST,SOCS6,SLC38A10,CDC25B,MRPL48,MRPL11,PACS2,IMPA2,RNF5,ERMP1,GALC,AACS,HNRNPF,POLR3GL,FRAT2,GALK2,NFATC2IP,UBE4B,VDAC1,ANLN,MAPK3,ANKRD10,HHEX,OSBPL11,PRDX3,NDUFA11,ACAT1,QRSL1,YWHAZ,MDH1,RBBP4,GLCCI1,HIGD2A,AAAS |
| 2.021e-06 | -13.11 | GSE27786_CD8_TCELL_VS_MONO_MAC_UP | MSigDB lists | GSE27786_CD8_TCELL_VS_MONO_MAC_UP | 186 | 53 | 17377 | 2626 |
PPCS,RWDD1,IVNS1ABP,BABAM1,JMJD6,CDK13,NKRF,IL21R,ABHD14A,HMG20A,ATPAF1,ZBTB45,IARS,HUWE1,BANF1,PHF14,FBXO7,EI24,SUCLG2,RNASEH2A,PTGES3,TOP1MT,CNOT6L,ZNRD1,ZNF800,SMC4,USP34,FOXK1,DDX24,NEK7,ADSL,SLC25A22,NFATC2,MEF2D,KDM1B,STK17B,MAP2K2,GNAS,MRPL2,PDCD6,TIMM13,DUS3L,MLYCD,MDH1,DVL1,IDH3B,NGLY1,IGBP1,SMAD4,ZC3HAV1,IPO4,SSSCA1,S100PBP |
| 2.021e-06 | -13.11 | GSE3982_NEUTROPHIL_VS_BCELL_DN | MSigDB lists | GSE3982_NEUTROPHIL_VS_BCELL_DN | 186 | 53 | 17377 | 2626 |
MMACHC,MUM1,CUTA,LAGE3,RRM1,PXMP2,FAM136A,GGA2,BCAT2,IRF4,CLIC4,CTNNBL1,IARS,UTP18,AKR1B1,GEMIN6,RPAP1,YBX1,RPN2,NFU1,MRPL40,UBE3C,CPSF4,SEH1L,PRPF19,PTPRK,ATP13A1,POLR2G,BIRC3,ABCF2,GTPBP4,RPL8,ESYT1,SOX4,MBD3,APPL1,TARS,CYB5A,STOML2,AKAP1,DTWD1,MAP3K4,RPL32,HINT1,UAP1,PFDN4,DCK,PTER,KPNA2,RUVBL2,HEXA,TRAF5,TMEM131 |
| 2.021e-06 | -13.11 | GSE12392_CD8A_POS_VS_NEG_SPLEEN_IFNB_KO_DC_UP | MSigDB lists | GSE12392_CD8A_POS_VS_NEG_SPLEEN_IFNB_KO_DC_UP | 186 | 53 | 17377 | 2626 |
TCF12,DNAJC2,GCLM,DNMT3A,TOR3A,TAP1,MRPS26,NIT2,PARK7,MAT2B,PSMD1,XPA,FAM89B,TCEA1,AHCYL1,DNMT1,RPRD1B,DRAM2,MYO5A,KDM3B,MKLN1,POLR2G,CREG1,PRKDC,GBA,RNPS1,PSMA1,ANAPC2,MAP4K3,UTP3,MEN1,PRPSAP1,FOXRED1,MAK16,LSG1,EIF3A,CYB5A,PRDX1,HHEX,OSBPL11,MTHFD2,GALNT2,VPS26B,ACOX1,MRPL27,STAT1,GLG1,PKD2,NDE1,MRPL13,PGAM1,CPEB2,DDX52 |
| 2.021e-06 | -13.11 | GSE12001_MIR223_KO_VS_WT_NEUTROPHIL_DN | MSigDB lists | GSE12001_MIR223_KO_VS_WT_NEUTROPHIL_DN | 186 | 53 | 17377 | 2626 |
TCF12,USP7,RAB14,TRIM41,SMAP1,GGNBP2,XAB2,MECP2,GPR89A,CDT1,SCYL1,FAM76A,EIF2AK4,XPO7,HCFC1R1,PRPF39,BIRC2,PIP5K1C,RNFT1,PELO,SOCS6,PDCD2,DCP1A,FAM76B,ATF2,TMBIM1,CGGBP1,ALDH9A1,RPAP3,YTHDC1,CYFIP1,ADAM17,ERMP1,BIRC3,AATF,PSMA8,EID1,DDX20,RCOR1,WDR82,FAM133B,BCLAF1,C9orf40,KDM3A,BTBD1,ZMYM3,DNAJC10,SAFB,IARS2,ACADM,ARRB2,CBX4,GPR89B |
| 2.030e-06 | -13.11 | GO_MITOTIC_RECOMBINATION | MSigDB lists | GO_MITOTIC_RECOMBINATION | 41 | 19 | 17377 | 2626 |
POLA2,ERCC1,RFC3,PRIM2,SMC6,TOP2B,RFC2,RAD54B,RPA1,PRIM1,RPA2,RAD51C,PCNA,POLE,NSMCE2,XRCC2,XRCC3,GEN1,RAD51D |
| 2.030e-06 | -13.11 | AMUNDSON_GAMMA_RADIATION_RESPONSE | MSigDB lists | AMUNDSON_GAMMA_RADIATION_RESPONSE | 41 | 19 | 17377 | 2626 |
PLK1,PTTG1,CENPF,KIF23,KIF2C,AURKB,CCNB1,CCNF,CDKN2C,KIFC1,CCNA2,PPP2R5A,H2AFX,PRC1,CDC25B,UBE2C,CCNB2,ESPL1,TACC3 |
| 2.040e-06 | -13.10 | DAIRKEE_CANCER_PRONE_RESPONSE_BPA_E2 | MSigDB lists | DAIRKEE_CANCER_PRONE_RESPONSE_BPA_E2 | 113 | 37 | 17377 | 2626 |
RAB14,ABCA3,TXN,TKT,RPL15,EBNA1BP2,AP3S1,APLP2,PSMA6,BCAP29,FBL,EEF1D,PDPK1,IFRD1,RPL29,MAPKAPK3,RRM2,USP10,PKMYT1,EIF4G2,DDX39A,MARK2,EIF3A,CHAF1A,SUPT16H,RPL36,HMGN2,PPP2CA,EPRS,MKNK1,SEC61A1,COX8A,KHSRP,UQCRH,HMGB2,SRSF3,H3F3A |
| 2.060e-06 | -13.09 | MYH9 (myosin heavy chain 9) | protein interactions | 4627 | 318 | 84 | 17029 | 2761 |
USP7,IMMT,CYLD,LUZP1,IVNS1ABP,ACTR3,RAC1,CUL1,CSNK2A1,UBE2I,TWF2,SEC16A,LYN,GNB2,BCAP31,DST,SHC1,CCDC50,EIF4A3,PIK3R2,AP2B1,TARDBP,CLTB,CFL1,CDC5L,KDM3B,ATG9A,BRCA1,MCM2,ANLN,EIF3A,EPB41,PPP2CA,AHNAK,PEX5,DSN1,CORO1C,MYO18A,SEL1L,ACTB,ARRB2,PPP1R12A,FLOT1,CDCA8,PAWR,RAB11A,MYL6B,CDC73,JMY,RPA2,HUWE1,KIF13B,MCM5,CAPZA1,GTSE1,H2AFY,AHDC1,GNAI2,MYO5A,MICAL3,TERF2,SPTAN1,PPP1R9B,WDR1,TUFM,SRSF5,SYVN1,CAPZA2,PLEC,SEPT7,MEN1,MACF1,PICALM,DAPK3,ISG15,RPA1,GNAS,INF2,NAP1L1,YWHAZ,WDR76,ATP5F1A,CDK2,TERF1 |
| 2.068e-06 | -13.09 | MODULE_126 | MSigDB lists | MODULE_126 | 172 | 50 | 17377 | 2626 |
MIF,FOXM1,PHB2,WDYHV1,DAP,TCF3,CENPF,DBF4,TPX2,RRM1,CSNK2A1,CCNB1,SLC20A1,ITGB5,HDDC2,FBXO5,CDK5,PDXP,PCNA,GART,CCNA2,NEK6,DUT,YIF1B,MAST2,METTL9,MSH6,ABCC1,PPIF,GCC2,RFC3,MAPKAPK3,ASPM,MKI67,ADSL,SLC25A22,SMC2,SLC25A5,ODC1,DUSP3,TFDP1,PTPN7,IARS2,E2F1,KHSRP,HMGB2,PPP5C,SLC25A33,HDAC2,POLQ |
| 2.073e-06 | -13.09 | COPII vesicle coating | biological process | GO:0048208 | 63 | 25 | 17256 | 2622 |
USO1,TRAPPC9,GORASP1,CUL3,MCFD2,RAB1A,PEF1,SEC16A,ANKRD28,CD59,SEC31A,SEC23IP,PDCD6,GOLGA2,NSF,TMED10,SEC24C,PPP6C,PPP6R3,TFG,LMAN1,PPP6R1,TMED2,CSNK1D,PREB |
| 2.073e-06 | -13.09 | vesicle targeting, rough ER to cis-Golgi | biological process | GO:0048207 | 63 | 25 | 17256 | 2622 |
USO1,TRAPPC9,GORASP1,CUL3,MCFD2,RAB1A,PEF1,SEC16A,ANKRD28,CD59,SEC31A,SEC23IP,PDCD6,GOLGA2,NSF,TMED10,SEC24C,PPP6C,PPP6R3,TFG,LMAN1,PPP6R1,TMED2,CSNK1D,PREB |
| 2.080e-06 | -13.08 | TGOLN2 (trans-golgi network protein 2) | protein interactions | 10618 | 56 | 24 | 17029 | 2761 |
INTS2,RAB14,PPP1R9B,NUP188,NF1,GOPC,CHD1L,RUFY1,XPR1,KIAA1147,RAD51C,RAB18,GALNT2,POLE,INTS1,TBL3,ARF5,ITGB1,PDS5B,AP1M1,LTN1,INTS12,GPD1L,NUP85 |
| 2.086e-06 | -13.08 | nuclear envelope disassembly | biological process | GO:0051081 | 48 | 21 | 17256 | 2622 |
PLK1,NDC1,NUP188,RAE1,NUP54,NUP155,CCNB1,LMNA,NUP205,NUP210,NEK6,BANF1,NUP107,NUP62,NUP153,CCNB2,NUP58,NUP85,SEH1L,AAAS,DCTN1 |
| 2.086e-06 | -13.08 | membrane disassembly | biological process | GO:0030397 | 48 | 21 | 17256 | 2622 |
PLK1,NDC1,NUP188,RAE1,NUP54,NUP155,CCNB1,LMNA,NUP205,NUP210,NEK6,BANF1,NUP107,NUP62,NUP153,CCNB2,NUP58,NUP85,SEH1L,AAAS,DCTN1 |
| 2.090e-06 | -13.08 | XAB2 (XPA binding protein 2) | protein interactions | 56949 | 67 | 27 | 17029 | 2761 |
SNRNP200,CDC40,SUZ12,PPIE,CRNKL1,ILF3,CUL3,DHX8,PRPF3,DHX15,POLR2A,DDX23,SF3B2,EIF4A3,GLIS2,DHX16,EFTUD2,XPA,YJU2,KIFAP3,SNRPG,AQR,ISY1-RAB43,ZNF830,NKAPD1,IFI16,PRPF19 |
| 2.113e-06 | -13.07 | GSE7460_CTRL_VS_TGFB_TREATED_ACT_FOXP3_HET_TCONV_UP | MSigDB lists | GSE7460_CTRL_VS_TGFB_TREATED_ACT_FOXP3_HET_TCONV_UP | 191 | 54 | 17377 | 2626 |
WSB2,UBE2D3,GLT8D1,IMMT,PLXNC1,TMEM41B,SLC2A1,DBF4,NUP54,JMJD6,CHAC2,ORC1,LACTB2,ITGB5,HDDC2,TFAP4,SLC31A1,PDXP,MDM2,EIF2S2,ATP2A2,ZNF639,TPST1,PCYT2,OSTC,TMEM8A,LMAN1,ATF2,PCBP2,ABCC1,UBE2QL1,SAP30,SNX25,PHF10,TMEM39A,POLR2D,TUFM,GORASP2,DCUN1D5,ICAM2,ANKRD46,YIF1A,HSPA4,SYNCRIP,SEC61A1,TMED10,PROSER1,PPP3R1,SIAH2,GPI,PGAM1,LRP8,APOL2,PTOV1 |
| 2.119e-06 | -13.06 | PRMT5 (protein arginine methyltransferase 5) | protein interactions | 10419 | 179 | 54 | 17029 | 2761 |
CTDP1,DNMT3A,CYLD,TCF3,OLA1,RPL15,SMARCA4,ARGLU1,SNRPD3,WDR5,MYEF2,ARID1B,WWP2,DST,RBM23,VASP,UBE2Q2,CTNNBL1,SHC1,EIF4A3,MCM5,AHSA1,MBD2,CTPS1,NSFL1C,RBM3,FAM76B,FBL,CHTOP,PDIA6,SMARCE1,TERF2,FOXK1,DCAF8,SNRPB,CUL3,CIRBP,BRCA1,MEF2D,GAR1,LUC7L,CLNS1A,POLR2A,JAK1,CLK3,LSM6,ZNF436,YWHAZ,SNRNP70,ARRB2,SMURF1,TERF1,CAPN1,PDCD4 |
| 2.121e-06 | -13.06 | Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. | REACTOME pathways | R-HSA-163200 | 113 | 39 | 10287 | 1696 |
COX5B,NDUFA5,NDUFV2,NDUFS1,NDUFB6,NDUFAF2,UQCR10,NDUFA4,COX4I1,CYCS,ATP5F1B,ATP5PF,SDHA,NDUFS7,NDUFS4,NDUFAF6,NDUFV1,NDUFA2,NDUFB4,NDUFB9,NDUFS8,CYC1,NDUFA3,TIMMDC1,TMEM126B,COQ10B,NDUFA7,ATP5MF,NDUFB1,SDHB,ATP5MC3,COX7A2L,NDUFA11,COX8A,LRPPRC,COX5A,UQCRH,ATP5F1A,NDUFS5 |
| 2.122e-06 | -13.06 | ubiquitin-protein transferase activity | molecular function | GO:0004842 | 448 | 106 | 17224 | 2647 |
MIB2,UBE2E2,MPHOSPH8,TRAF7,TRIM11,UBR2,XIAP,UBE2Q1,UBE2Z,KLHL18,CUL1,NHLRC3,UBE2I,BIRC2,ANKIB1,RNF103,FBXO22,ZER1,FANCL,MDM2,FBXL6,CDC42,SIAH1,FBXW2,TTC3,MARCH2,RNF19A,RNF26,SPSB3,RLIM,PRPF19,BIRC3,RBX1,VHL,RNF25,CUL3,TOPORS,UBE2V1,BRCA1,CDC23,CCNF,TRIM28,RAD18,UHRF2,RNF38,TRIM32,KLHL42,FBXL3,SMURF1,ZNF598,UBE2D3,RMND5A,TRIP12,KLHL21,SHPRH,ZFP91,CBLL1,BRAP,ZNRF3,UBE4A,WWP2,DTL,RFWD3,FBXO3,HERC3,RNF121,UBE2Q2,KLHL20,MED10,KLHL5,HUWE1,ZNRF2,FBXO7,PPIL2,FEM1B,LTN1,FBXL7,UBE3B,UBE3C,RNF135,FBXL19,LRSAM1,UBE2M,RNF5,UBE2QL1,LONRF3,TNFAIP3,RFFL,FBXO9,ANAPC2,SYVN1,UBE4B,FBXO21,KEAP1,FBXO41,BIRC5,KLHL15,DTX4,KBTBD7,SIAH2,PPP1R11,UBE2C,RNF14,RNF139,ANAPC4,RNF114 |
| 2.148e-06 | -13.05 | HALLMARK_PROTEIN_SECRETION | MSigDB lists | HALLMARK_PROTEIN_SECRETION | 96 | 33 | 17377 | 2626 |
RAB14,SCAMP3,ADAM10,COPE,VPS45,ARF1,AP3S1,STAM,COPB2,DST,NAPG,AP2B1,LMAN1,TMED2,TMX1,CLCN3,USO1,PPT1,GALC,SNX2,STX16,RAB22A,SEC31A,GNAS,GOLGA4,ATP1A1,TMED10,SNAP23,ERGIC3,ANP32E,MAPK1,ABCA1,AP2S1 |
| 2.148e-06 | -13.05 | KCCGNSWTTT_UNKNOWN | MSigDB lists | KCCGNSWTTT_UNKNOWN | 96 | 33 | 17377 | 2626 |
MAX,ZFP91,ENSA,CTCF,CSNK1A1,FOXO3,RBM4,CNOT3,CRKL,HNRNPA2B1,SMC3,CCNA2,KDM2A,FIZ1,AKAP8,TRA2B,ZNF524,ILF3,E2F3,LRRC1,EIF4G2,KDM3A,PICALM,DHX15,CBX3,DDX17,DAP3,SYNCRIP,OGT,ACLY,DDX5,SRSF3,RBPJ |
| 2.165e-06 | -13.04 | BENPORATH_MYC_TARGETS_WITH_EBOX | MSigDB lists | BENPORATH_MYC_TARGETS_WITH_EBOX | 220 | 60 | 17377 | 2626 |
SRM,TCF12,BCL2L12,RHOG,RPS15,TOMM20,H2AFZ,TXN,TSC2,NOP2,FOXM1,UROD,SLC4A2,IRF3,ARF1,CCNB1,RGS2,STMN1,APP,TFRC,LMNA,EBP,RPL23A,HNRNPA2B1,MDM2,PTEN,CLCN6,RPL19,BCL2,RBM3,PABPC1,IMPA2,TGFB1,PLK1,AMPD2,SIGMAR1,VHL,AMD1,NSUN2,SLBP,ELK1,RPL27A,ARF4,CLNS1A,HMGN2,AKAP1,RXRB,MAN2A2,SLC19A1,ETS2,GOLGA7,DCK,STAT6,ACOX1,DBI,ITGB1,E2F1,ACTB,ACADM,ZNF146 |
| 2.167e-06 | -13.04 | REACTOME_TRANSPORT_OF_MATURE_TRANSCRIPT_TO_CYTOPLASM | MSigDB lists | REACTOME_TRANSPORT_OF_MATURE_TRANSCRIPT_TO_CYTOPLASM | 52 | 22 | 17377 | 2626 |
SRSF11,CDC40,NUP188,RAE1,SRSF6,RBM8A,RNPS1,NUP54,SLBP,NUP155,SRSF5,NUP205,SRSF1,NUP210,SRSF4,NUP107,NUP62,NUP153,SRSF3,NUP85,AAAS,SEH1L |
| 2.188e-06 | -13.03 | GSE39022_LN_VS_SPLEEN_DC_DN | MSigDB lists | GSE39022_LN_VS_SPLEEN_DC_DN | 177 | 51 | 17377 | 2626 |
GCLM,CDS2,RAF1,ADO,MCCC1,KLF13,NKRF,TOP2B,MXD4,CDIPT,MAPK14,PARN,HMG20A,ARID1B,C2orf68,PRNP,THADA,RABGAP1L,BDH1,NSFL1C,CITED2,GPD1L,RPL22L1,CCAR1,SMC4,NOL12,FTL,ELOVL5,NOL8,LDB1,ZBED5,TUFM,HSDL1,BCLAF1,NDRG3,XRCC5,MAGED2,VEZF1,TPD52L2,SERTAD2,CCDC86,LUC7L3,RBMX,WDR91,PITRM1,PDSS2,SSSCA1,RAD51D,GPATCH4,ESYT2,S100PBP |
| 2.188e-06 | -13.03 | GSE2770_TGFB_AND_IL4_VS_IL4_TREATED_ACT_CD4_TCELL_6H_DN | MSigDB lists | GSE2770_TGFB_AND_IL4_VS_IL4_TREATED_ACT_CD4_TCELL_6H_DN | 177 | 51 | 17377 | 2626 |
RMND5A,FGFR1OP,FAM208B,DNAJC5,B4GALT5,GADD45G,NUP54,CHAC2,ZNF267,COMMD5,PRKACA,GLRX3,CMTM6,RGS1,EBP,AHCTF1,PSMA6,SYNM,SIVA1,PPME1,RNASEK,ATP6V0A2,AHDC1,SPTSSA,MCMBP,NAA35,SAP30L,PREB,ELOF1,RPAP3,PPIF,BAK1,ARHGAP17,CREG1,NET1,IDH3A,AMD1,GTPBP4,TOPORS,TOLLIP,MAK16,ZDHHC3,SMAP2,DAPK3,AKAP1,MASTL,CAND1,KIF2A,CDK2,PURA,NIPA1 |
| 2.188e-06 | -13.03 | GSE40666_STAT1_KO_VS_STAT4_KO_CD8_TCELL_UP | MSigDB lists | GSE40666_STAT1_KO_VS_STAT4_KO_CD8_TCELL_UP | 177 | 51 | 17377 | 2626 |
GMFG,MRPS15,TOR1AIP1,TWF2,MAPK14,ANKIB1,ASAP2,CTNNBL1,NDUFA2,CCP110,NVL,TIMELESS,KIF22,NDUFS8,KNTC1,CYC1,NAP1L4,TALDO1,PLCL2,NDUFA3,GTF2H2,ZNRD1,HDHD2,CTDSP2,POC5,IMPA2,HMGN5,PRIM2,ANKRD37,GABPA,NOA1,MBLAC2,UTP3,SMC2,GSTCD,ARMC8,RFC2,PRPSAP1,BBS12,PRIM1,MBIP,L3MBTL3,QARS,CDCA7L,DUSP11,SPRYD4,CHEK2,TFDP2,AP2S1,SNX14,TIGD2 |
| 2.200e-06 | -13.03 | GSE360_LOW_DOSE_B_MALAYI_VS_M_TUBERCULOSIS_DC_UP | MSigDB lists | GSE360_LOW_DOSE_B_MALAYI_VS_M_TUBERCULOSIS_DC_UP | 196 | 55 | 17377 | 2626 |
IER2,NCOR2,CYLD,H2AFZ,ADD1,PHB2,DAP,NACA,TMEM109,TKT,CTCF,ASAH1,COX4I1,GGA2,S1PR2,ITGB5,FOXO3,CNOT3,NDUFS4,MDM2,ADD3,SIVA1,DUT,H2AFY,ANP32A,AHCY,FBL,CLTB,SMARCE1,KDELR1,ABCC5,ADCY7,CDC5L,SPTAN1,MLEC,CSRP1,TSPYL4,ERF,IDH3A,SUGP2,HEBP2,NDUFA7,H2AFV,TARS,CAT,SEC31A,MAN2A2,MAGED2,STK38,MPV17,PQBP1,MEGF9,LTA4H,SSRP1,PTOV1 |
| 2.206e-06 | -13.02 | positive regulation of cell cycle process | biological process | GO:0090068 | 278 | 72 | 17256 | 2622 |
UBE2E2,KMT2E,POC1A,SIRT2,CCNB1,PRKACA,BECN1,APP,PCNA,MDM2,CDC42,KIF14,CDKN1B,CDC25B,CARM1,PLK3,BRD4,BTG2,CUL3,CDC6,NUSAP1,LRP5,AURKB,BRCA1,SOX4,PAF1,RAD51C,RPS27A,NSMCE2,E2F4,UHRF2,XRCC3,CHEK2,TFDP2,GEN1,SLF1,KIF3B,PKP4,PHB2,MECP2,CDT1,KIF23,RACGAP1,CRLF3,PAGR1,CNOT11,RAB11A,CDC73,CNOT3,SPAG5,DDRGK1,DTL,RB1,CENPJ,H2AFY,GTSE1,CNOT6L,TGFB1,RHOA,CNOT9,CDCA5,TFDP1,PML,FAM83D,E2F1,NUP62,CNOT6,PKD2,UBE2C,CDK2,SLF2,ESPL1 |
| 2.207e-06 | -13.02 | positive regulation of gene expression | biological process | GO:0010628 | 1878 | 355 | 17256 | 2622 |
ZNF496,H2AFZ,CXXC1,HEXB,YTHDF3,CCNL2,CCNB1,EDRF1,PARK7,GLMP,USF1,NOL11,DNM2,TRA2B,ECD,ZNRD1,DNMT1,SENP1,CDC5L,KLF10,AATF,GABPA,TOPORS,USP22,CBFB,SLC50A1,ARF4,DOT1L,HHEX,SMAD2,RPS27A,AXIN1,OGT,RNASEL,TFDP2,SMAD1,ARRB2,E2F2,HDAC2,DDX58,HIVEP3,HSPH1,POLR2K,PRKAA1,DHX9,EZH1,EIF2AK4,PSMD9,PSEN1,METTL3,CDC73,LMNA,DDRGK1,TFAP4,FOXN2,MYDGF,PABPC1,NUP85,NSUN4,TMED2,TERF2,EIF5A,FOXK1,MTA2,MYBL2,BCLAF1,EXOSC9,ARID1A,SRSF5,ADRB2,ELK1,FXR1,KDM3A,MAP2K2,TWISTNB,SERTAD2,ETS2,SETD3,RBMX,PIAS2,PPP3R1,CEBPG,YY1,MAP3K5,RNF14,CDK2,EGLN1,RHOG,KARS,TRERF1,IVNS1ABP,RPS6KA1,SF3B1,RAF1,EIF3D,MAGED1,ANK3,MYH9,CREBL2,APP,CCNA2,SHC1,SP100,GMEB1,LPIN2,MRPS27,MAVS,RBM15,ATF2,RPRD1B,CDK12,PSRC1,BRD4,POLR2L,CDC123,KAT7,WBP2,POLR2D,CIRBP,E2F3,EDF1,MEF2D,SERP1,TRIM28,SUPT16H,DDX17,TAF2,VEZF1,SAFB,HIPK2,STAT1,TICAM1,ATF6,ATMIN,POU3F2,NCOR2,MECP2,TCF3,HABP4,ABHD14B,SECISBP2,WDR5,BLM,ETS1,FOXO3,MAD2L2,WWP2,GTF2F1,CCNK,PDCD10,ITGB8,PTEN,PRDM4,AXIN2,CARF,CITED2,CREB1,NCOA2,PPP3CA,KAT2A,RFXANK,ILF3,ZP3,KLF6,PICALM,FADD,POLR2A,HGS,GPS2,PITX1,TFDP1,PML,DDX5,HMGB2,CD81,USF2,YWHAH,RORB,CCNC,ZBED3,ZNF76,IER2,HNRNPAB,THOC1,AGRN,AAMDC,KMT2E,GPBP1L1,FAM129A,SIRT2,MAPK14,CREM,TET3,ZNF804A,GLIS2,EIF4A3,ZNF639,ETV6,PIK3R2,MYBL1,ARID4A,CARM1,ELOF1,RYBP,SRPK2,SP3,DEAF1,NCK1,VHL,MRPL12,EZR,UBE2V1,LRP5,BRCA1,EAF2,SOX4,USP21,UBTF,PAF1,E2F4,BAZ1B,ACTB,ZNF268,CHEK2,ROCK1,DVL1,CLU,PSMC1,FUBP1,ZNF564,PPP1R12A,NKD2,CHCHD2,CTCF,MEF2A,CDK13,PPP3CB,THRAP3,RLF,ASXL2,CRLF3,EPHX2,ARID1B,RHBDD1,SUB1,RB1,MLX,NFATC3,MED10,SSBP3,ZNF746,CTR9,ICE2,RBM3,YBX1,MDFIC,MAML1,ERLIN1,LDB1,UTP15,KRAS,RTF1,EIF2A,NFATC2IP,IRF5,CAND1,RXRB,PSMC4,SYNCRIP,NFIL3,TBPL1,NLRC5,NUP62,ZFP90,RUVBL2,SNRNP70,TOB1,SMARCD1,TCF12,PRKAB1,ASH1L,FOXM1,SMARCA4,PLAGL2,IRF3,PCBP1,PAIP1,RPL11,RRN3,NRF1,MDM2,CD3EAP,PIN1,TARDBP,F2R,DVL2,PRPF19,MOSPD1,POU2AF1,POLR2G,NFATC2,RPS9,SRSF1,RBL1,SCAP,STAT6,TIMM17A,ARNTL,PLGRKT,NCOA1,H3F3A,AKNA,MAPK1,SMAD4,NAT14,SLC30A9,BCL2L12,DNAJC2,EYA1,AGO2,KLF13,PAWR,NKRF,HMGN3,PAGR1,FASTKD3,IRF4,BRD7,ARHGEF2,H2AFY,SS18L1,POLR1B,STAT3,TGFB1,COA3,DCAF6,RHOA,HMGN1,HMGN5,PRKDC,PRMT2,MEN1,MAPK3,TFEB,HSPA1B,ATAD2,TFE3,E2F1,KMT2B,PKD2,RBPJ,NR2F2,ZMIZ1,HRAS,IFI16 |
| 2.244e-06 | -13.01 | ubiquitin protein ligase binding | molecular function | GO:0031625 | 310 | 79 | 17224 | 2647 |
USP7,ATXN3,MPHOSPH8,KDM4A,SUMO2,CUL1,UBE2Z,UBE2I,PRKACA,BECN1,MAP1LC3B,RPL11,MOAP1,FANCL,PA2G4,MDM2,PSMD1,CCDC50,NEK6,RALB,PCBP2,CCT2,RBX1,CUL3,UBE2V1,BRCA1,DNAJA1,SLC25A5,TRIM28,BTBD1,SMAD2,RAD18,JAK1,RPS27A,AXIN1,ARRDC1,ATP6V0C,ATF6,CHEK2,CLU,TRAF5,ARRB2,SLF1,TUBB,USP13,DDX58,SCAMP3,SHPRH,UBXN1,NKD2,SMC6,FZD6,NPLOC4,RPA2,RB1,ZNF746,TANK,FBXO7,AXIN2,BCL2,UBE2M,ERLIN1,RFFL,ANAPC2,ISG15,POLR2A,HSPA1B,XRCC5,MFN2,DERL1,HSPBP1,PIAS2,LRPPRC,PML,YWHAZ,GPI,UBE2C,SLF2,FAF1 |
| 2.252e-06 | -13.00 | ZC3HAV1 (zinc finger CCCH-type containing, antiviral 1) | protein interactions | 56829 | 140 | 45 | 17029 | 2761 |
RPS15,COX15,NIFK,NOP2,IVNS1ABP,RAE1,EBNA1BP2,USP48,BRIX1,APP,KRR1,MEX3C,RPL17,RBM34,AHSA1,YBX1,TARDBP,HP1BP3,NOL12,STAU1,DDX24,ZNF574,GTPBP4,CUL3,RPL8,LLPH,AURKB,BRCA1,MAK16,SLTM,ISG15,CAND1,RPL36,NSA2,UPF1,ZNF777,RPL32,DGCR8,NIP7,H2AFX,BAZ1B,WDR76,RRS1,IFI16,GPATCH4 |
| 2.260e-06 | -13.00 | SMARCA4 (SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4) | protein interactions | 6597 | 220 | 63 | 17029 | 2761 |
NCOR2,ADD1,NF1,ARID2,PMS2,TOP2B,NSD3,REEP5,MYEF2,ARID1B,RB1,USF1,RAP1A,MDM2,SMC3,PELO,BRD7,SS18L1,CREB1,MAML1,MCPH1,STAT3,SMARCE1,CARM1,CDC5L,PHF10,BRD4,CUL3,RCOR1,NFATC2,BRCA1,ARID1A,PBRM1,MBD3,TRIM28,POLR2A,CAND1,CAT,KPNA1,SMAD2,UPF1,BRWD1,ETS2,RBL1,NEIL3,MYO18A,STAT1,PML,BCL7C,H2AFX,BAZ1B,STK11,KPNA2,DDX5,ACTB,RBPJ,NCOA1,H3F3A,RBBP4,CDKN2A,HDAC2,BYSL,SMARCD1 |
| 2.267e-06 | -13.00 | regulation of mRNA catabolic process | biological process | GO:0061013 | 181 | 52 | 17256 | 2622 |
AGO2,DHX9,YTHDF3,SECISBP2,THRAP3,PSMD9,MAPK14,PARN,METTL3,PAIP1,PABPC4,FASTKD3,PSMD2,PSMA6,PSMD1,EXOSC7,METTL14,EXOSC1,AXIN2,DCP1A,ANP32A,YBX1,TARDBP,CNOT6L,PABPC1,SAMD4B,EXOSC6,POLR2G,PSMA8,BTG2,PSMB7,CIRBP,TBRG4,PSMA1,EXOSC9,FXR1,PSMB9,PSMB3,PSMC4,UPF1,SYNCRIP,HNRNPR,RPS27A,PSMD8,PSMD3,E2F1,KHSRP,YWHAZ,RNASEL,TOB1,PSMC1,ZC3HAV1 |
| 2.269e-06 | -13.00 | ANXA5 (annexin A5) | protein interactions | 308 | 71 | 28 | 17029 | 2761 |
ZNF207,HARS,MRPL12,KRAS,BRCA1,SND1,NANS,ITGB5,SDHA,CPNE3,APP,ISG15,TERF2IP,PA2G4,PDCD6,DNAJC8,HUWE1,CS,H2AFX,GPI,FUS,CDK2,ATF2,TERF1,PPA1,TUBB,TERF2,FDFT1 |
| 2.269e-06 | -13.00 | SEC13 (SEC13 homolog, nuclear pore and COPII coat complex component) | protein interactions | 6396 | 71 | 28 | 17029 | 2761 |
EWSR1,MIOS,FLYWCH2,CUL3,BRCA1,PPWD1,MCM2,SPDL1,CSNK1A1,SEC16A,RAB11A,PICALM,SEC31A,WDR44,AHSA1,WDR59,NUP107,YJU2,GTSE1,FUS,CLTB,TFG,SLC12A2,TRAF5,NUP85,IFI16,SEH1L,PRPF19 |
| 2.269e-06 | -13.00 | DNMT3B (DNA methyltransferase 3 beta) | protein interactions | 1789 | 71 | 28 | 17029 | 2761 |
DNMT3A,BAZ2A,MTA2,SUZ12,RPS10,CUL3,CUL1,RTF1,SMC2,UBE2I,MAP1LC3B,NCAPG,CMTM6,CDC73,TRIM28,POLR2A,MBD4,CBX3,PAF1,MTA1,UHRF2,CTR9,PCYT2,CREB1,RBBP4,DNMT1,HDAC2,SMC4 |
| 2.276e-06 | -12.99 | Nuclear Envelope Breakdown | REACTOME pathways | R-HSA-2980766 | 52 | 23 | 10287 | 1696 |
PLK1,NDC1,NUP188,NEK7,RAE1,NUP54,NUP155,CCNB1,NUP205,LMNA,LEMD2,NUP210,NEK6,BANF1,LPIN2,NUP107,NUP62,NUP153,CCNB2,NUP85,NUP58,AAAS,SEH1L |
| 2.303e-06 | -12.98 | RPL7A (ribosomal protein L7a) | protein interactions | 6130 | 175 | 53 | 17029 | 2761 |
RPS15,RPS2,CYLD,EWSR1,RPLP2,MECP2,RPL15,EBNA1BP2,BRIX1,RPL11,RPL23A,EIF4A3,RPL17,HUWE1,RBM34,ZNF746,RPL19,TARDBP,PABPC1,LUC7L2,HNRNPM,STAU1,RPL29,RPL35,VHL,MRPL12,RPS10,RPL6,CUL3,RPL8,ILF3,RPL38,RPS24,BRCA1,MCM2,RPL27A,SLC25A5,MAK16,RPS9,RPSA,RPL36,UPF1,RPL32,DGCR8,RPS27A,QARS,RPS14,RPLP1,RRS1,ARRB2,RPS26,ZC3HAV1,GPATCH4 |
| 2.303e-06 | -12.98 | GSE2770_TGFB_AND_IL4_VS_IL12_TREATED_ACT_CD4_TCELL_48H_UP | MSigDB lists | GSE2770_TGFB_AND_IL4_VS_IL12_TREATED_ACT_CD4_TCELL_48H_UP | 182 | 52 | 17377 | 2626 |
SRM,DNMT3A,CDC40,MIF4GD,TKT,ACAP1,ABHD14B,XPO7,OAT,KCMF1,PIP4K2A,RSAD1,JMY,CDK5,ARF5,PIK3R2,XPA,ANP32A,MRPL40,RNF135,GPD1L,TMEM14C,ARL5A,CAMK2G,MLST8,MAPRE2,PTPN18,NXT1,PPT1,DCAF8,WDR18,EIF2AK1,NFATC2IP,RHOT1,H2AFV,KDM3A,HAGH,NDRG3,STX16,SNRPA,MAPK3,TRAM2,EIF2D,EXOC4,TMEM219,FN3KRP,MBOAT1,HMGB2,ARRB2,CHPT1,SSSCA1,FAF1 |
| 2.303e-06 | -12.98 | GSE15930_STIM_VS_STIM_AND_IL-12_72H_CD8_T_CELL_UP | MSigDB lists | GSE15930_STIM_VS_STIM_AND_IL-12_72H_CD8_T_CELL_UP | 182 | 52 | 17377 | 2626 |
SEPHS2,MIF4GD,COPA,IVNS1ABP,PRPF39,SYNRG,KCMF1,TTF1,POLR3K,FZD6,MAT2B,SEC11A,MCM5,TANK,BUD31,FBXW2,BRD7,ATG13,MAST2,CNN2,ATF2,TMEM14C,NCOA2,PREB,PTPN18,CSRP1,GABPA,KAT7,TIGD5,ATXN1,EMP3,FRAT2,DNAJC9,NUSAP1,GALK2,DNAJA1,CAPZA2,MEF2D,NUTF2,ANLN,MRPS14,ASF1B,ISG15,ANKRD10,AXIN1,LRPPRC,HMGB2,ROCK1,RBBP4,CHPT1,PSMC1,S100PBP |
| 2.303e-06 | -12.98 | GSE17721_0.5H_VS_12H_LPS_BMDC_UP | MSigDB lists | GSE17721_0.5H_VS_12H_LPS_BMDC_UP | 182 | 52 | 17377 | 2626 |
IER2,MRPL42,ZFP91,SF3B1,BABAM1,MRPS26,ZFYVE21,C19orf48,LCLAT1,XPR1,KIFC1,CDKN2C,GOLM1,PCNA,UCHL5,IL6ST,TBC1D14,BDH1,ABCD1,RPL19,TECR,ALDH18A1,ATP6V0D1,GPX4,GINS1,ELOVL5,PPP3CA,TK1,RPL35,SEC61B,NUDT4,KIAA0930,SLC26A6,ARHGDIB,GALK2,TMEM147,VDAC1,SLC50A1,MATR3,ASF1B,MAPK3,HAUS8,HSPA4,MRPL55,H2AFX,ACAT1,CENPT,NCOA1,PPP2R2D,MRPL3,IPO4,HIGD2A |
| 2.303e-06 | -12.98 | GSE22886_NAIVE_TCELL_VS_DC_UP | MSigDB lists | GSE22886_NAIVE_TCELL_VS_DC_UP | 182 | 52 | 17377 | 2626 |
RPS15,LIME1,RPLP2,TSC22D3,NACA,ACAP1,PCSK7,BTN3A1,SAFB2,RPL11,NRF1,ADD3,MZT2A,SP100,RPL17,BCL2,RPL19,CDC25B,PIK3IP1,PLCL2,ALDH18A1,CNNM3,EEF1D,SPSB3,RPL29,MAPRE2,RPL35,PBXIP1,TSPYL4,LRBA,SLC16A7,RPL38,RPL6,RPS10,RNPS1,DIDO1,CYFIP2,ICAM2,ARHGAP15,RPL36,EIF3K,FBXO21,PFDN5,RPS14,STK38,WDR59,FAU,MZT2B,C7orf26,PDCD4,N4BP2L2,ADNP2 |
| 2.303e-06 | -12.98 | GSE18791_CTRL_VS_NEWCASTLE_VIRUS_DC_14H_UP | MSigDB lists | GSE18791_CTRL_VS_NEWCASTLE_VIRUS_DC_14H_UP | 182 | 52 | 17377 | 2626 |
TP53RK,RRP15,MTX3,URB2,SHPRH,MRI1,UROD,KIAA0232,MRPS26,SLC25A12,ZFYVE21,SUMF1,EBNA1BP2,IFT27,GIT2,PCYOX1L,ADD3,SUV39H2,ZNHIT6,PPP4R1,NSFL1C,GEMIN6,CTR9,TARDBP,CORO1A,TNRC18,STRAP,COPS8,DDX28,ZNF559,SNRNP200,FAM172A,MIOS,NUDT4,TUBGCP5,SCFD2,JTB,ARID1A,C9orf40,ICMT,FOXRED1,FBXO21,RAD51C,QARS,UBXN2B,TATDN2,PRPS2,IMPDH1,FAM126A,OSGEPL1,CHPF2,ATMIN |
| 2.303e-06 | -12.98 | GSE10239_NAIVE_VS_KLRG1INT_EFF_CD8_TCELL_UP | MSigDB lists | GSE10239_NAIVE_VS_KLRG1INT_EFF_CD8_TCELL_UP | 182 | 52 | 17377 | 2626 |
CTU2,ANKRD13D,FAM208B,AGRN,UBR2,HMGXB3,CCM2,ARID5A,KLF13,MED13L,RLF,UBLCP1,PAIP2,RPL11,PRKD3,CTSS,IL6ST,TRMU,ZDHHC13,RPL19,PIK3IP1,SCYL3,NCOA2,NTPCR,RPL35,RHOA,SELPLG,RPL38,MFNG,RFXANK,SLC25A22,MEF2D,TANC1,RPL27A,ARSK,RAB2B,FAS,KRIT1,PI4K2A,RPL37,ZNF777,RPL32,RPS14,STAT6,WDR59,GLG1,DNAJC17,RPLP1,MLYCD,DUSP11,DVL1,USP53 |
| 2.324e-06 | -12.97 | BTF3 (basic transcription factor 3) | protein interactions | 689 | 39 | 19 | 17029 | 2761 |
RPL29,FGFR1OP,POC1A,NACA,SMC6,CNTROB,MATR3,APP,RPL11,PCM1,PDRG1,CENPJ,H2AFX,RWDD4,BTF3L4,TXLNA,PDCD4,IFI16,DCTN1 |
| 2.324e-06 | -12.97 | TRAP1 (TNF receptor associated protein 1) | protein interactions | 10131 | 119 | 40 | 17029 | 2761 |
ZNF207,USP7,COX15,NANS,EIF2AK4,SND1,EXT2,APP,CPNE3,PARK7,CRKL,CDK5,RB1,PA2G4,DNAJC8,DUT,CS,ANXA5,MCPH1,CFL1,CDC5L,MRPL12,CUL3,VDAC2,WDHD1,PKM,VDAC1,OGFR,SF3A2,PSMC4,MAGED2,KIF2A,HGS,PRDX5,H2AFX,FKBP5,GPI,LTA4H,MYL12B,SMAD4 |
| 2.324e-06 | -12.97 | ATP5F1C (ATP synthase F1 subunit gamma) | protein interactions | 509 | 119 | 40 | 17029 | 2761 |
POLA2,COX15,IMMT,NDUFS1,SUZ12,CHCHD2,NDUFA4,PAWR,ATP5F1B,ATP6V1B2,APP,PNO1,NDUFS4,SSR1,RPN1,EIF2S2,PTEN,HUWE1,AHSA1,ZNF746,ZFYVE27,NDUFB9,TECR,LMAN1,ATP6V0D1,ELOF1,STAU1,ATP5IF1,CUL3,VDAC2,ADRB2,VDAC1,CHMP2B,MCM2,ATP1A1,DDOST,MED15,ACADM,ATP5F1A,SPRYD4 |
| 2.346e-06 | -12.96 | GSE23321_CD8_STEM_CELL_MEMORY_VS_NAIVE_CD8_TCELL_UP | MSigDB lists | GSE23321_CD8_STEM_CELL_MEMORY_VS_NAIVE_CD8_TCELL_UP | 168 | 49 | 17377 | 2626 |
HSPH1,FAM207A,TRMT6,RBM8A,CSNK2A1,AGFG1,SLC35B1,IKBIP,S1PR2,ZNF79,RBM17,FARSA,PSMD2,ZNF326,EI24,PARL,TNPO2,YBX1,MAST2,ECD,TOP1MT,STRAP,MRPL32,SRSF10,TNFAIP3,KLF10,DPM1,PRKDC,RNPS1,SLC17A5,EIF4H,RHOB,PHF6,YIF1A,SDHB,SURF4,TTLL4,TIMM17A,PPM1G,NFIL3,LMBR1,CHMP4B,RRS1,NANP,PDCD11,CD81,HDAC2,B4GALT2,ADNP2 |
| 2.358e-06 | -12.96 | regulation of cellular protein catabolic process | biological process | GO:1903362 | 234 | 63 | 17256 | 2622 |
USP7,ATXN3,SUMO2,UBXN1,NKD2,SIRT2,UBQLN2,CSNK1A1,PRKACA,PSEN1,BCAP31,ANKIB1,RIC1,PARK7,FBXO22,DDRGK1,USP5,RAD23A,RPL11,MDM2,PTEN,UCHL5,DDA1,RAD23B,RNF19A,SENP1,PDCL3,SOCS5,RYBP,PLK1,PLK3,UBQLN4,ATP5IF1,LONRF3,TNFAIP3,RBX1,PBK,GBA,EZR,EDEM2,PTTG1IP,HSPA1B,PSMC4,GNA12,KEAP1,HSPBP1,HIPK2,AXIN1,SOCS4,OGT,PML,CLU,DVL1,WDR91,CD81,SMURF1,RNF14,PSMC1,RNF139,CSNK1D,SVIP,RNF114,USP13 |
| 2.370e-06 | -12.95 | regulation of proteolysis involved in cellular protein catabolic process | biological process | GO:1903050 | 205 | 57 | 17256 | 2622 |
USP7,ATXN3,SUMO2,UBXN1,NKD2,SIRT2,UBQLN2,CSNK1A1,PRKACA,PSEN1,BCAP31,ANKIB1,PARK7,FBXO22,DDRGK1,USP5,RAD23A,RPL11,MDM2,PTEN,UCHL5,DDA1,RAD23B,RNF19A,SENP1,PDCL3,SOCS5,RYBP,PLK1,PLK3,UBQLN4,ATP5IF1,LONRF3,RBX1,PBK,GBA,EDEM2,PSMC4,HSPA1B,GNA12,KEAP1,HSPBP1,HIPK2,AXIN1,SOCS4,OGT,PML,CLU,DVL1,SMURF1,RNF14,PSMC1,RNF139,CSNK1D,SVIP,RNF114,USP13 |
| 2.411e-06 | -12.94 | GSE27786_CD8_TCELL_VS_NEUTROPHIL_UP | MSigDB lists | GSE27786_CD8_TCELL_VS_NEUTROPHIL_UP | 187 | 53 | 17377 | 2626 |
PPCS,ST13,TAP1,AP3M2,CUL1,NKRF,INO80E,GLRX3,METTL3,ABHD14A,RPAIN,HMG20A,TUBGCP2,ATPAF1,RRP36,PTPN2,PDXP,EIF2S2,ZNF260,POP7,SLC35B4,MRPL34,TRA2B,APOOL,TTLL12,SLC12A2,ZNRD1,IFT46,CCAR1,RLIM,SRSF11,SNRNP200,FAM172A,DDX24,TSTA3,PGGT1B,HELB,NOL8,LDB1,TUBGCP5,NDRG3,PHF6,POLR2J,ARNTL,SLC25A19,ZFP90,SPRYD4,RBBP4,ZNF598,SMAD4,MRPL3,ZC3HAV1,RHEBL1 |
| 2.411e-06 | -12.94 | GSE9960_GRAM_POS_VS_GRAM_NEG_AND_POS_SEPSIS_PBMC_UP | MSigDB lists | GSE9960_GRAM_POS_VS_GRAM_NEG_AND_POS_SEPSIS_PBMC_UP | 187 | 53 | 17377 | 2626 |
SLC12A7,SEPHS2,TCF12,DNAJC2,TRIM41,ASH1L,PKP4,DNMT3A,MUT,SCOC,MRPS2,MAGED1,C5orf30,PCSK7,SUMF1,SPR,METTL3,EEF2K,NUDT19,VAV1,DECR1,SMC3,EXOSC7,TBC1D14,MOB1A,EEF1D,KDM3B,CPNE1,EID1,PRKDC,PPP1R21,LDB1,ZNF574,MAP4K3,WDR81,NUTF2,LY6E,ICAM2,FOXRED1,GFER,TTC33,EIF3G,RHOB,PRDX1,RAB18,POLR2J,PDRG1,PKD2,RGL1,NDE1,SMAD1,TOB1,PTOV1 |
| 2.411e-06 | -12.94 | GSE43863_TH1_VS_LY6C_LOW_CXCR5NEG_EFFECTOR_CD4_TCELL_UP | MSigDB lists | GSE43863_TH1_VS_LY6C_LOW_CXCR5NEG_EFFECTOR_CD4_TCELL_UP | 187 | 53 | 17377 | 2626 |
GALK1,DNAJC2,CHTF18,PDAP1,PTTG1,CENPF,TPX2,RRM1,NUF2,HAUS4,CNTROB,BLM,NCAPG,PNO1,RFWD3,CDKN2C,FKBP1A,PSMD1,CCNA2,MED8,NEK6,TIMM23,UCHL5,EI24,GTSE1,MRPL54,SEPT11,KIF22,MAST2,MRPL11,SLC12A2,DNMT1,PABPC1,TMEM160,PLK1,TIMP2,MKI67,RRM2,SSR2,UBE2V1,TOMM40,SHCBP1,KIF11,ASF1B,SLCO4A1,NRM,H2AFX,CHEK2,GPI,SPCS3,PPP5C,MZT2B,ESPL1 |
| 2.411e-06 | -12.94 | GSE15330_MEGAKARYOCYTE_ERYTHROID_VS_GRANULOCYTE_MONOCYTE_PROGENITOR_IKAROS_KO_UP | MSigDB lists | GSE15330_MEGAKARYOCYTE_ERYTHROID_VS_GRANULOCYTE_MONOCYTE_PROGENITOR_IKAROS_KO_UP | 187 | 53 | 17377 | 2626 |
HSPH1,SARNP,NUP188,VPS45,CUL1,PXMP2,NENF,CHAC2,PARN,CUTC,SDHA,RBM4,PARK7,KIFC1,MRPL50,FKBP1A,EIF4A3,UTP18,HDAC7,ETV6,MEA1,MRPL54,PRADC1,TFG,PDIA6,LPCAT1,TMEM14C,EEF1D,ALDH9A1,AMPD2,NXT1,ACP2,GUK1,POLR2G,NSUN2,TYW1,NUTF2,SF3A2,LSG1,TMEM184C,ATP1A1,SEC23IP,DDOST,MRPL55,MAGT1,NEIL3,ACLY,SLC16A1,HMGB2,EHD4,CHPT1,TSEN15,TMEM33 |
| 2.411e-06 | -12.94 | GSE40184_HEALTHY_VS_HCV_INFECTED_DONOR_PBMC_DN | MSigDB lists | GSE40184_HEALTHY_VS_HCV_INFECTED_DONOR_PBMC_DN | 187 | 53 | 17377 | 2626 |
SLC12A7,OTUD5,ZNF76,RWDD1,GPBP1L1,SRGN,ARID5A,ACAP1,PLAGL2,UBE2Q1,TMED3,FKBP2,MFSD10,MED10,RABGAP1L,JAZF1,BANF1,PRDM4,SRI,ATP6V0A2,TAP2,PCYT2,SGCB,F2R,UBE2M,S100A6,ELOF1,TSHZ1,NRAS,POLR2I,DENND4C,ANAPC2,BICD2,DCLRE1C,LY6E,MAP2K2,OPTN,EPB41,INF2,NUCB1,UPF1,SURF4,DDOST,FAM110A,FASTK,PITPNA,PIEZO1,GPI,SMURF1,NRBP1,AAAS,BYSL,DDX42 |
| 2.411e-06 | -12.94 | GSE33162_HDAC3_KO_VS_HDAC3_KO_4H_LPS_STIM_MACROPHAGE_UP | MSigDB lists | GSE33162_HDAC3_KO_VS_HDAC3_KO_4H_LPS_STIM_MACROPHAGE_UP | 187 | 53 | 17377 | 2626 |
USP7,SART1,NSMCE4A,FAM207A,SEC61G,CDT1,BABAM1,PMS2,MYO9B,NOTCH2,PRPF39,CDK11B,FOXO3,REPS1,CMTM6,KTN1,PIP4K2A,CRKL,DNAJC8,SNX18,TBC1D14,PPP4R1,MDFIC,RBM15,S100A6,SPSB3,CGGBP1,RLIM,PDPK1,RBM42,TSTA3,RAB7A,BTG2,GTPBP4,BOLA1,NFATC2IP,RAB3IP,APPL1,RAB22A,SERP1,SH3GLB1,SERTAD2,OSBPL11,SAFB,MAPK6,CAB39,STK11,CHMP4B,FBXL3,HEXA,USP53,NUMB,RHEBL1 |
| 2.411e-06 | -12.94 | GSE29618_PRE_VS_DAY7_FLU_VACCINE_PDC_DN | MSigDB lists | GSE29618_PRE_VS_DAY7_FLU_VACCINE_PDC_DN | 187 | 53 | 17377 | 2626 |
RPS15,HSPH1,SART1,PLXNC1,PPP1R12A,COPA,MEF2A,UBE4A,GGPS1,CRLF3,PIP4K2A,TTF1,MYEF2,FBXO22,TERF2IP,RFWD3,RAB8A,LRRC8D,CAPZA1,BUD31,TNPO2,AP2B1,LTN1,MDFIC,OSTF1,EIF5,ORC3,ATF2,STRAP,RBM15B,BRD4,HARS,NCK1,PSMG1,HEBP2,EAF2,ADRB2,CYFIP2,MPG,API5,KLF6,MAT2A,ZFR,EIF3A,GNAS,KPNA1,SMAD2,DCK,ACLY,RBMS1,TAF12,FAM208A,FAF1 |
| 2.411e-06 | -12.94 | GSE9601_NFKB_INHIBITOR_VS_PI3K_INHIBITOR_TREATED_HCMV_INF_MONOCYTE_UP | MSigDB lists | GSE9601_NFKB_INHIBITOR_VS_PI3K_INHIBITOR_TREATED_HCMV_INF_MONOCYTE_UP | 187 | 53 | 17377 | 2626 |
GNPDA1,SHPRH,MUM1,HNRNPUL2,FAM76A,ENSA,MAPK14,ZADH2,GOLM1,PDK2,DECR1,MLX,PIK3R2,MAVS,CYB5R1,MRPL40,CNNM3,IFT46,ILKAP,ADCY7,ERMP1,ACP2,KLF10,POLK,BTG2,TYW1,TMEM216,DNAJC9,CDC23,PRKRA,VDAC1,TAZ,RFC2,USP21,ANKRD46,RDH11,HAUS8,TFEB,AMZ2,CDKN2AIPNL,IDE,CLK3,VPS26B,QARS,APPL2,BAZ1B,ACAT1,WIPI2,LTA4H,YWHAH,SNX14,ZMAT3,FAF1 |
| 2.415e-06 | -12.93 | PHGDH (phosphoglycerate dehydrogenase) | protein interactions | 26227 | 115 | 39 | 17029 | 2761 |
USP7,SUZ12,EPN1,THRAP3,APP,CDC73,PABPC4,RAD23A,HUWE1,RAD23B,GTSE1,CRY2,TARDBP,GPD1L,PABPC1,SRSF10,LDHB,CDC5L,RPAP3,SRSF11,PRKDC,SMU1,CUL3,BRCA1,SRSF5,CHMP2B,MCM2,ISG15,SRSF1,CAND1,SURF4,RPS27A,MAPK6,STAT1,FUS,CLN3,CDK2,PGAM1,SSRP1 |
| 2.429e-06 | -12.93 | transferase complex, transferring phosphorus-containing groups | cellular component | GO:0061695 | 275 | 70 | 18223 | 2701 |
BCCIP,CCNC,POLA2,PRKAB1,TAF6L,CCNL2,CCNB1,BECN1,POLR3K,CCNA2,INTS1,PIK3R2,INTS12,TAF5L,TCEA1,ZNRD1,RPRD1B,CDK12,WDR41,ERCC1,POLR2L,POLR2G,POLR2D,EDF1,ERC1,PRIM1,TAF2,PAF1,CRCP,CAB39,INTS2,CTDP1,POLR2K,ZNF768,PRKAA1,CDK13,CDC73,MAD2L2,NEXMIF,GTF2F1,CCNK,RB1,MED8,MED10,INTS7,CTR9,ATG13,POLR1B,GTF2H2,PHKG2,RPRD1A,POLR2I,PRIM2,KAT2A,RB1CC1,HELB,POLR3GL,RTF1,PKM,POLR2A,TWISTNB,POLE,POLR2J,PRDX3,PRPS2,TBPL1,TAF12,MAP3K5,TAF6,CDK2 |
| 2.450e-06 | -12.92 | large_intestine-rectum-carcinoma-adenocarcinoma | COSMIC cancer mutations | large_intestine-rectum-carcinoma-adenocarcinoma | 16326 | 2479 | 17385 | 2587 |
HECA,ZBTB10,ABCC10,HEXB,TGOLN2,CCNL2,FBXO22,EEF2K,THAP4,RAD23B,ATP13A3,DNM2,ZNRD1,FTSJ3,USP34,CCDC57,ERCC1,NRAS,EHMT1,KIF15,HNRNPF,WDHD1,MIER2,DIDO1,MCM2,RAB22A,SMAD2,MID1IP1,RPS27A,MYO18A,OGT,MPV17,COX5A,SMAD1,ZNF75A,ANXA11,SLC25A33,SEC61G,GGA1,MUM1,CCZ1,TRIO,CUTA,RAB23,HAUS4,EIF2AK4,APH1B,PARN,CDC73,MYL6B,ATG4A,ERV3-1,PDXP,SMC3,GEMIN4,MVP,NUP85,PPP6R1,PABPC1,NSUN4,PPA1,IFRD1,AGGF1,FOXK1,RBM42,GTPBP4,MAP7D1,MRPL16,ELK1,EIF4H,RDH11,MAGED2,KPNA1,ETS2,TYW5,WIPI2,RUFY3,PDLIM5,ACSF2,EXOC3,RHOG,STARD7,C5orf30,VTI1A,SLC35B2,INO80E,RCOR3,LCLAT1,CPNE3,RBM23,ZNF420,AHCTF1,TBC1D22A,TBC1D14,GMEB1,NSFL1C,SEPT11,GPD1L,ZC3H3,ARL5A,PDCL3,SNX8,ERMP1,EID1,IDH3A,POLR2D,HTATIP2,MEF2D,TMEM147,GSTCD,TANC1,MAT2A,VPS26B,NSMCE2,CORO1C,CAMKMT,PPP5C,PITRM1,TUBB,COMMD10,ZNF445,SRSF6,HABP4,CCM2,FLOT1,BTN3A1,ATG2B,ABHD14B,PPP1R3B,GOLM1,ZBTB45,HUWE1,ZNF260,NAA50,ANXA5,LTN1,UBE3B,NAP1L4,ZNF710,ST8SIA2,MED22,SPTAN1,STAU1,DDX24,TCTEX1D2,TACC1,MRS2,LDHA,HEBP2,LLPH,RAB3IP,TTC33,PICALM,SH3BP5,SLC19A1,ACOX1,FAM3C,AEN,PARP10,YWHAH,THAP5,GPATCH4,FAM129A,TRIM11,YTHDC2,SNX15,RBM8A,ENSA,NENF,SND1,RUFY1,TRIM65,ZER1,PRNP,KRR1,RAB8A,NUP210,NT5DC1,NOC2L,EIF5,TACC3,VPS13B,PTPN18,MIOS,MBLAC2,SNRPB,CDC6,UTP3,PBRM1,ODC1,USP21,TRAM2,FBXO28,BCL7C,ARRDC1,ADAM9,DVL1,NUMB,ZNF564,FUBP1,C1orf74,PARP12,ZCCHC9,CENPF,LAMTOR3,CHCHD2,NCKAP1,LYRM2,RSAD1,TNS3,SUB1,RINL,SSBP3,KIF13B,MBD2,XPA,AHCY,RBM3,GLE1,MRPL48,LRSAM1,HDHD2,NTPCR,NSDHL,AMD1,CAMSAP1,ZNF761,METTL22,ICAM2,STYXL1,APPL1,BBS12,RXRB,SDHB,PCM1,GALNT2,TMEM168,NLRC5,RUVBL2,MYO9A,BTBD10,CCNB2,USP7,GLT8D1,RPLP2,SUCLG1,ARID2,TMX4,SLC2A1,ATP6V1B2,PCBP1,LYN,BCAP31,VAV1,TMEM69,MRPL50,PSMA6,ZNF473,ZNF302,BRPF3,TARDBP,BCAP29,CTDSP2,PRPF19,PPIF,KDM3B,MND1,CLCN3,BIRC3,RAB7A,PPIE,CHMP2B,VDAC1,EIF3H,GLOD4,IDE,DHX16,UHRF2,CHMP4B,XRCC3,PARD3,BCL2L12,C19orf53,MCM10,KLHL21,PDAP1,TMX3,CDCA8,ARF1,SLC12A9,TUBGCP2,DNAJB9,HOMER1,POLR1B,RNF5,RBM15B,PPAN,RHOA,RPRD1A,BTAF1,TOP3A,ARHGEF12,PCGF1,DDX23,RAB18,CACNB1,TRIM26,PDCD6,ATP6V1D,L3MBTL3,FAM110A,NEIL3,CTBS,BBX,IMPDH1,TAF12,NR2F2,PGAM1,HIPK3,IFI16,TXN,NUP188,H2AFZ,PNISR,PRKCSH,USP39,UBE2I,PARK7,SLC25A37,ZNF428,RAB4A,TRA2B,SUCLG2,TAF5L,SMARCE1,ZNF800,CDC5L,ZNF524,SGCE,OSBP2,NSUN2,USP22,CLNS1A,EIF3A,ZMYM3,DOT1L,IWS1,ANKRD10,WAS,KIF18B,TPP2,C1orf109,ZMAT3,B4GALT2,PRPF38B,RECQL,C9orf78,EWSR1,GADD45G,RRM1,ACAP1,B4GALT1,CYCS,SUPT7L,TMEM165,NPLOC4,CNOT3,WDR48,SPAG5,RTKN,CEP104,EXOSC7,KLHL5,LRRC8D,PPP4R1,MSH2,PIGG,FBXL7,OSTF1,MRPL40,SYTL3,FAM171A1,APOL1,EIF5A,GCC2,PRIM2,ELL2,RDH10,MFNG,RPS24,GORASP2,CAPZA2,ADRB2,CCT8,MTR,PHF6,PFDN5,SLCO4A1,TTC13,GOLGA2,RBMX,MED15,PIAS2,APPL2,SAMD8,NUDT3,CDKN2A,ZNF511,ATXN3,RAF1,KIAA0232,C2orf49,EPM2A,CD320,CCNA2,MTMR4,BRI3,TP53BP2,AQR,RBM12B,ILKAP,CDK12,SAP30,BRD4,DRAP1,NARF,LRRC8A,ELP4,ABHD11,PKMYT1,ASB13,SERP1,TRIM28,SUPT16H,EIF3K,CHMP4A,CBWD1,ATF6,XRCC4,PRPF4B,ADAM23,NDUFS1,DEPDC1,MECP2,SECISBP2,HMG20A,WWP2,JAKMIP1,SLC25A36,DNAJC8,AXIN2,CITED2,JMJD4,ANKRD37,KAT2A,TMEM126B,RABIF,ADSL,PACS1,BMS1,KCNQ1,OTUD3,ARSK,MACF1,KIF11,KLF6,COMMD4,SMAP2,FADD,SH3GLB1,MYO1F,CBX3,TMEM127,INF2,PPP1R11,DUSP11,DDX5,WDR62,TAF6,ESPL1,PURA,DDB1,DEF6,IPO4,FAM83G,UBL3,NAT9,PIGM,LYRM4,GPR132,UBE2Q1,PTP4A3,BRIX1,MRPL19,ZNF696,SF3B2,PCYOX1L,CDC42,SYNM,GOT2,JAZF1,HADHB,RPF2,SLC35C2,CNNM3,CARM1,SRPK2,WDR41,LARS,ZCCHC10,CCDC138,LRBA,TMEM216,SUMF2,KMT2C,OGFR,PRPSAP1,ASF1B,RPL37,MAN2A2,EIF4ENIF1,NIP7,U2SURP,MIA2,ZNF268,VPS4A,ATP6V0E1,PPP1R2,XPNPEP3,RGS2,LYAR,FAM89B,POLR2I,TRAFD1,SUGP2,GBA,EIF2A,SYVN1,DAPK3,ARHGAP15,MASTL,UAP1,NFIL3,FN3KRP,YWHAZ,CTSA,TMEM14A,TOB1,TSEN15,ADNP2,TCF12,PRKAB1,MDH2,SMARCA4,ORC1,RRN3,UBXN2A,IARS,CD3EAP,KIF14,EXOSC1,CS,CLTB,DNAL4,CSTF1,POU2AF1,UBQLN4,NXT1,HPDL,PGGT1B,SELPLG,SMU1,ATXN1,GLO1,OGDH,BICD2,CADM1,EDEM2,HERPUD2,TOLLIP,FANCE,MBD3,PDHX,RPS9,ALKBH6,SURF4,DUS3L,ARNTL,ANP32E,FKBP5,TMEM101,CCDC125,ABCA1,PDCD2L,GCLM,RAE1,DCTN2,NUP54,CHIC2,PAWR,MXD4,DCUN1D4,PIP4K2A,XPR1,FERMT3,KIF5B,KLHL20,SEC24C,RRBP1,ARHGEF2,ANP32A,LDLRAD3,C12orf75,STAT3,MYO5A,NIPAL3,AMPD2,TXNL1,PHF20L1,DCAF6,FAM49B,TMEM39A,ATP2C1,RFFL,COG1,RCOR1,PRMT2,TFEB,LEMD2,UPF1,ELMO1,ZC3H7B,DTX4,ZMIZ1,TERF1,HRAS,CCDC93,FGFR1OP,TMED7,PIGQ,AGPAT1,CNTROB,PPP1R16B,MIS12,GSDMB,TTC9C,PDS5B,NUP153,SENP1,PGAP2,TMEM115,DCUN1D5,PLEKHF2,BRMS1,PWWP2B,TRIM47,WDR11,AXIN1,SMG9,TRIM52,LONP2,NDUFV2,PHF23,CERK,SLC4A2,EZH1,ITGB5,LMNA,MCTS1,DDX56,EIF2S2,SLC38A5,FOXN2,CARS2,PRRC2A,C16orf72,RB1CC1,ZMYND11,PGS1,MYBL2,UHRF1BP1,SRSF5,MPG,MATR3,CYB5A,NCDN,POLR2J,SETD3,CNOT6,NDE1,EGLN1,ZNF207,ANKRD27,ABCA3,SARNP,IVNS1ABP,RMI2,MON1B,TMEM97,NIT2,NUF2,ZNF267,TCF19,TMEM161B,KTN1,APP,PRKD3,CLUAP1,ATP2A2,UTP18,GRSF1,DUT,ZCCHC2,ANAPC7,RNF19A,FAM76B,CLN6,TMEM9,GCC1,RNF169,ADCY7,ATP6V1G1,ENPP4,RNPS1,CDCA2,FKBP3,GPR137,DDX17,CHCHD3,PEX5,CDC16,HIPK2,MBOAT1,TICAM1,PDXK,ZBTB11,ANXA6,TMBIM4,GMCL1,UBE4A,IL21R,ETS1,WRB,ZNF92,PNO1,CAPN2,ADD3,SUV39H2,TTLL12,TPCN1,TMX1,LYPLA2,HNRNPM,MFSD12,LDHB,PPP3CA,NUDT8,POLK,JTB,EMP3,MTMR12,ZP3,PDE3B,KIF18A,CCDC6,WNT5B,MAPK6,C4orf46,LY75,SLC25A19,RGL1,PSAP,WDR76,IGBP1,FAF1,COX15,THOC1,AGRN,GNPDA1,GPBP1L1,PPP1R15B,CSNK2A1,EBNA1BP2,GIT2,BIRC2,ATPAF1,DLG5,ABL2,XRCC2,ZFYVE27,MCMBP,PTPRK,CDC37,METTL1,SP3,EXOSC6,HARS,GMFB,ESYT1,ANLN,RAB5B,RHEB,DPYSL3,TBC1D17,TIMM13,CDCA4,TONSL,NRM,NAGLU,ACTB,ZNF45,TMUB1,CTCF,ASAH1,DOCK11,CRLF3,ASXL2,LRRC14,NUS1,SLC27A4,AFF1,MDFIC,MAML1,CYTH1,NQO2,UTP15,EIF2AK1,EIF4G2,ZDHHC3,MOSPD3,ITPRIPL1,CDC27,SNAP23,TBPL1,PRMT7,KCTD7,NDUFA5,CYLD,UGP2,DYNLL1,COPE,HCFC1R1,ZADH2,GGPS1,RPAIN,RAD23A,PDK2,ATP6V0B,STRBP,DUS4L,MRPL34,PDCD2,SAP30L,SLC39A9,CLPTM1,RPL29,RPL35,BTG2,DNAJC9,MTMR6,FRAT2,NFATC2,KDM1B,ARL5B,USP36,MRPL2,ATP1A1,CLK3,PSMD3,MAFK,CEP55,NDUFA11,DNAJC17,ZNF436,NCOA1,SLC25A39,ZC3HC1,ZNF146,ATXN7L2,CDC40,GOLIM4,SMAP1,RRP15,DAP,GNE,SMC6,ARFIP2,NKRF,CHAC2,BZW2,WRNIP1,SS18L1,CENPM,PTGES3,CAMK2G,MLEC,ZNF202,PPWD1,FAM50B,RHOT2,NEU1,TPD52L2,GOLGA7,TWSG1,PGRMC1,GLG1,FAM126A,RPS6KC1,UBE2C,PPCS,NDUFB6,TMEM41B,ZDHHC8,PLXNA1,CCNB1,SLC20A1,COMMD6,ABHD14A,POLR3K,C14orf119,ASAP2,SNUPN,CNPY4,TFG,PLCL2,SEH1L,ATG9A,PBK,MKI67,DDX20,AMDHD2,GALNT7,SLC17A5,CCNF,FOXRED1,RBM47,PTER,WDR4,DHTKD1,TRAF5,HDAC2,PWWP2A,HSPH1,LIME1,MAPRE1,CHTF18,KIF23,SLC35B1,NOTCH2,PMF1,JMY,FKBP1A,SLC31A1,SNX18,ATIC,CTPS1,ATP6V0A2,PIKFYVE,RNF135,LPCAT1,EEF1D,TMED2,FTL,PHF10,DDX28,ZNF84,SIGMAR1,PIP4K2C,FAM133B,RIT1,PLEC,KDM3A,SF3A2,FAS,EPRS,ZNF777,TMEM54,QARS,PPP3R1,TCOF1,NRBP1,CABLES1,DNMT3A,RWDD1,CKLF,TRIP10,SF3B1,RPS6KA1,CAST,SUZ12,RAC1,GPR89A,OLA1,SNN,GNB2,FLAD1,APLP2,KDM2A,TNPO2,CDKN1B,TALDO1,GPX4,ATP13A1,RFC3,MAPRE2,ERF,CUL3,SLBP,KIAA1586,H2AFV,POLG2,GAR1,PSMB9,DHX57,NSA2,HSPA4,MRPL55,JAK1,TBL3,SEL1L,H2AFX,KLHDC4,B4GALT3,PDCD11,ATMIN,POLQ,POU3F2,OTUD5,NCOR2,ANKRD13D,PKP4,SCAMP3,CDCA3,SLC25A12,BLM,TMCC3,GTF2F1,CRAT,AHSA1,PRC1,UPF2,COPS7B,SLC38A10,CNOT6L,CNPY3,UBE2M,IFT46,TMEM160,TSHZ1,ZFP64,DENND4C,DENND1B,WDR18,RPL8,ILF3,LRRC1,RHOT1,TSR2,MARK2,ECH1,PRDX1,PLD3,NUCB1,FBXO21,GNA12,C1orf131,PRDX3,PFDN4,HNRNPH3,STX18,TFDP1,KHSRP,ASNA1,CPEB2,SSSCA1,BYSL,VPS29,S100PBP,MIB2,IER2,PTMS,NOP2,UBN1,DCAF15,NF1,FLYWCH2,ALKBH5,MOGS,TAF6L,MAPK14,BECN1,SNAPC4,RNF103,BCAT2,MBD4,C18orf32,METTL14,ZNHIT6,IMPAD1,RCSD1,PHTF1,SRI,KIF22,ZBTB22,NFU1,OGG1,TRIM14,ELOF1,COPS8,FYTTD1,TRIM8,RRM2,SOX4,ABHD5,CXXC4,UBTF,PAF1,UEVLD,SPATA2,PQBP1,IARS2,ATXN2L,GALNT10,STARD3NL,RPS15,PIGN,AGTRAP,CIB1,XPO7,SRRT,ZNF449,CAPZA1,GLTP,BCL2,KIFAP3,N4BP2,HP1BP3,THNSL1,ISG15,CAND1,GNAS,TSC1,RBM25,CDCA5,ZFP90,NANP,RBBP4,ZBTB24,SMARCD1,MBD1,WASF2,MMACHC,TOMM20,IFI27L1,GNPNAT1,HNRNPUL2,CHD1,MEAF6,C2orf68,CCDC50,AKAP8,PARL,RPN2,CHTOP,FAM3A,F2R,TMEM14C,SCYL3,ABI1,HTRA2,MOSPD1,RLIM,FAM172A,ZNF500,PSMB7,NLN,WIPF1,BOLA1,BUD13,NDUFB1,PEF1,BTBD1,TAB2,CHCHD1,TULP3,WDR59,CANT1,SCARB1,GAS2,USP11,SMURF1,TSPAN5,PPP2R2D,CDS2,MAGEH1,MRPL42,EYA1,CDK2AP2,MRPS26,LETMD1,KLF13,HDDC2,RGS1,MAN1A1,FBXO5,GART,PELO,TANK,BRD7,MRPL11,SAMD4B,ZDHHC18,POLR3GL,WDR81,MEN1,ZNF407,MFN2,COX8A,ZRANB2,MBD6,SRSF3,ATP6V1C1,IDH3B,TATDN1,TSC2,LACTB2,CMTM6,RBM4,ANKRD39,RPL23A,CDKN2C,USF1,DNAAF2,MECR,AP1M1,UPRT,CRY2,ECD,RNF26,TIPARP,LRRC59,ANKRD9,RHBDD2,MGAT5,ZNF559,RHOBTB3,GABPA,WBP1,NUTF2,ARF4,GINS4,KRIT1,BOLA3,AHNAK,RAD18,PDRG1,RNASEL,CHPF2,OAZ1,PDCD4,SMNDC1,NXT2,HIVEP3,KIAA0100,CLSPN,RHOC,DHX9,PDCD7,PSMD9,HAUS2,COPB2,TFAP4,CD59,RNFT1,RIMS3,MEGF8,EFTUD2,FBXO7,CPSF4,MRPL21,PHKG2,LUC7L2,SRSF11,EIF3L,MTA2,TYW1,USP10,ITM2A,SSR2,BCLAF1,MTX1,SFXN5,FNTA,PDLIM1,TXNDC16,ZNF830,MRPL3,ALS2,TRIM41,KARS,NQO1,POC1A,ANK3,PTTG1,TPX2,TBC1D13,DAZAP2,STMN1,GLRX3,C19orf48,REPS1,CBWD5,ABHD16A,FBXL6,SH3BP1,MTA1,UBA5,CLCN6,RPRD1B,SZRD1,CGGBP1,CPNE1,SEC61B,POLR2L,FAM118B,GOPC,E2F3,CIRBP,RPL38,CRNKL1,PFKFB3,GORAB,RAB1A,GIGYF1,TMEM184C,PPP2CA,KIF2A,CCDC14,LSM6,RNF38,SNRPG,DMWD,USP13,ZFP91,IP6K2,WDR5,SLC25A43,IFT27,PMVK,NEIL2,RRP36,SRXN1,RPA2,PSMD2,CLIC4,PDCD10,CBWD2,COQ4,ITGB8,ARF5,ARHGEF1,FBXL19,TTPAL,UTP20,MAGT1,GPS2,DBI,SSNA1,MRFAP1L1,CD81,TMEM131,WDR13,FANCI,PAPOLA,CREM,TET3,FANCL,GLIS2,IL6ST,INTS1,POP7,SLC44A1,MTPN,ASB6,PLK1,RPP25,SEPT9,CELSR2,RBX1,APH1A,RAD51AP1,ZBED5,CKAP2L,PSMG1,UBE2V1,EAF2,IL12RB1,KRTCAP2,LUC7L,LSG1,NECAP2,C1orf122,ALG3,TRIM4,AGPAT2,CHD3,ZNF367,E2F4,PRPF4,KPNA2,BEND6,CLN3,DNAJC30,FAM208A,NGLY1,POT1,MYL12B,CCDC137,RMND5A,HJURP,DNAJB2,FAM53C,NKD2,SDC2,KLC1,CDK13,ADCK5,COX4I1,DNAJB1,RAB6A,ARID1B,C1GALT1,MLX,UBE2Q2,CCP110,ZNF746,ARL6IP1,CTR9,NIPSNAP1,ABHD2,DCAF8,ACSL3,LDB1,MAP4K3,ARMC8,RBM38,NMT2,IRF5,RPL36,HAUS8,MBIP,ORMDL2,COX7A2L,ZDHHC7,SIL1,FAM122A,DTD1,UNC13C,BCCIP,SART1,TRAF7,TOR1AIP1,ZNF416,LAGE3,TM9SF3,ZFYVE21,RRAGC,ZNF121,OIP5,NRF1,WDR44,PPME1,PIN1,EFCAB11,RPAP1,CABLES2,LMAN1,AHCYL1,TOP1MT,STRAP,SPSB3,ZNF583,SNX25,ARHGAP17,POLR2G,ZNF780B,KIAA0040,PPT1,NUP155,DCLRE1C,MRPS14,RHBDF2,SUGP1,RBL1,FASTK,UBXN2B,STK38,AP1S1,SPRYD4,H3F3A,CHID1,SMAD4,RAD51D,SLC30A9,CMAS,UNK,NADSYN1,HMGN3,NCAPG,SCYL2,FZD6,HERC3,GTPBP3,CTSS,ORC3,RNLS,YTHDC1,ACP2,HMGN5,CSRP1,METTL5,ABCF2,TUFM,RANGAP1,PNPLA8,HAGH,API5,ZFR,SEC23IP,E2F1,TMEM219,USP20,RBPJ,PDCD6IP,MAX,LUZP1,GXYLT1,ADAM10,CXXC1,TSC22D3,AP3M2,CUL1,GYG1,NANS,OAT,MYEF2,ANKRD26,PA2G4,NOL11,FIZ1,ZNF200,SLC26A2,SRP72,KLF10,LACTB,CBFB,RFC2,RAB2B,MAP3K4,HHEX,LUC7L3,RPS14,MAP4,MRPL27,BTF3,PTPDC1,NMD3,CCDC59,PTOV1,COX5B,DNAJC5,SCOC,DHPS,POLR2K,ANKH,VAV2,PRKAA1,C16orf87,GSPT2,TATDN3,DLGAP4,PXMP2,PSEN1,ZNF79,PDXDC1,VPS25,NDUFS7,YY1AP1,C12orf10,FAM192A,RPN1,LHX8,ARPC5,ZNRF2,TPST1,DAPK1,PIK3IP1,CYC1,SOCS5,FDFT1,PIGT,EMB,WDR1,ZNF574,C1orf35,EXOSC9,ARID1A,PTTG1IP,C9orf40,FXR1,GOSR1,MAP2K2,TWISTNB,AKAP1,XRCC5,HMGN2,PI4K2A,SEC31A,CAT,DERL1,HSPBP1,MTHFD2,CEBPG,ARAP1,USP32,FAM83D,CABIN1,SMPD4,GPI,CYTIP,TP53RK,REPS2,RAB11B,UROD,SLC39A13,POMP,BCL2L1,DECR1,RALB,SIAH1,ADCY9,LPIN2,MRPS27,SOCS6,TTC3,RNASEH2A,CFL1,ANKLE2,CDC123,OAF,VDAC2,EDF1,ERC1,EML4,AMZ2,ANKZF1,ZNF282,RAD51C,DSN1,DDOST,HINT1,DGCR8,SAFB,HAGHL,RWDD4,FTSJ1,LMBR1,NCLN,BEND3,EYA2,DYNC1LI2,SLC41A1,B4GALT5,MANBA,TKT,FAM76A,CBLL1,ARGLU1,LANCL1,POFUT1,FAM8A1,HEATR5B,HLA-A,EBP,RFWD3,NDUFA2,FUT8,FJX1,BTF3L4,PTPN11,MRPL54,FEM1B,RPL19,CNN2,NDUFA3,MTX2,MSH6,PDLIM2,LONRF3,RFXANK,FBXO9,GUF1,RPL32,ZHX1,NDUFS5,WDR91,HIGD2A,ZBED3,RORB,POLA2,ZNF76,COPA,HMGXB3,PHRF1,ABCB10,COMMD5,MAP1LC3B,DST,SIVA1,RAB35,GPATCH1,TCEA1,DRAM2,DEAF1,TRAPPC13,SNRNP200,NCK1,LAP3,VHL,SREK1,ARHGDIB,PITPNB,HSPB11,BRWD1,PPM1G,SH3GLB2,CRCP,BAZ1B,CAB39,ACBD4,STK11,CLU,CHEK2,ZSWIM3,TSTD2,MRPL13,CHPT1,DCAF5,CAPN1,UBE2D3,NSMCE4A,PPP1R12A,ZCCHC8,GORASP1,NACA,UBXN1,EPN1,PCSK7,RPL15,THRAP3,TTF1,QSOX2,PRPF18,NUP205,CHKA,DTL,MED10,ZRANB1,MCPH1,SLC12A2,ATP6V0D1,CSNK1G3,CREG1,NUDT4,RPL6,VKORC1,SLTM,EVC2,KLHL15,SIAH2,SLC16A1,EHD4,SNRNP70,C11orf1,APOL2,N4BP2L2,SNX27,CHMP2A,CORO7,FEZ2,PMS2,UCK2,UCK1,CLCC1,EXT2,MXD1,USP5,HNRNPA2B1,SAP130,NVL,PPP6C,CYB5R1,ZNF770,EBAG9,RNF25,PCGF6,METTL2A,PON2,STAT6,HPS5,MAPK1,BRD9,TMEM33,NAT14,DNAJC2,TRIP12,SHPRH,SCYL1,VPS45,MYO9B,GFM2,SPPL2A,FASTKD3,FGFR3,PPIG,ZDHHC13,TMEM99,H2AFY,ATG13,NDUFS8,ERI3,FBL,SLC35A1,FRMD8,MICAL3,TGFB1,B3GALT6,ELOVL5,HEMK1,TIMMDC1,HELB,PSPC1,MIER1,SCFD2,NDRG3,CDK11A,MTMR3,ACAT1,CENPT,PLOD3,RAB3IL1,ZSWIM6,RAB14,ADD1,MRPS15,KDM4A,XIAP,DHX8,GLUD1,ANKRD23,PABPC4,CALM2,CDK5,PSMD1,NEK6,NSRP1,RABGAP1L,SRSF4,FNIP2,KCNAB2,PCBP2,MLST8,PLK3,ZNF672,MRPL43,HSDL1,TOPORS,MCL1,SMC2,PPFIA3,ICMT,STOML2,LIMK1,ZNF689,PRDX5,ATE1,MLYCD,ATP6V0C,ST3GAL2,FBXL3,TFDP2,E2F2,PFKP,AAAS,DDX42,SSRP1,MRPL9,MRPS2,STRN4,TOP2B,ZNRF3,TMED3,DDRGK1,RAVER2,GNS,INTS7,INPP5A,MCM5,PHF14,ZNF326,NAGPA,TIMM8B,ETV3,DHX29,TEX10,MAN1B1,RPS10,CBFA2T2,ABCF1,RHOB,LRRC14B,DTWD1,PTPRF,SCARB2,OSBPL11,CCDC86,DUSP3,SLAIN1,MDH1,HEXA,RNF139,SNX14,ZNF296,TRERF1,UBR2,CHD1L,ACTR3,WDTC1,MYH9,CREBL2,NIPA2,PRKACA,SAFB2,ANKIB1,STAM,ARL6IP6,RAB21,SP100,ZKSCAN1,DDA1,NUP107,ANKRD13C,MAVS,CEP63,TMEM136,RBM15,ATF2,DCTN1,SHOC2,PSRC1,MAP4K4,WBP2,ATP6V0A1,NDUFA7,DNAJA1,TAZ,TAF2,SEC61A1,WDR7,RPLP1,CBLN2,RBMS1,FUS,GEN1,LRP8,COIL,LRCH1,GALK1,ZNF786,RPS2,SESTD1,TRAK1,JMJD6,SIKE1,AKT1S1,KRI1,FBXO3,ERH,PPP1R8,PRDM4,GTSE1,GEMIN6,DCP1A,SGCB,S100A6,IMPA2,NUDC,PDPK1,TK1,GUK1,TNFAIP3,GALC,ZNF512,KIAA0930,MRPS10,DDX39A,RPA1,ZNF862,ZNF180,KEAP1,POLE,TATDN2,PITX1,CAPN7,LRPPRC,PML,HMGB2,USF2,ANAPC4,SRM,DDX47,MCCC1,CDC42SE2,S1PR2,CDIPT,SEC16A,SSR1,LIN9,PCNA,ZNF639,PIK3R2,ETV6,TXLNA,PPCDC,FAM86C1,MYBL1,MRPL32,CCAR1,ABCC5,PBXIP1,BAZ2A,TLK1,MRPL12,EZR,LNX2,LRP5,BRCA1,PRKRA,STX16,EPB41,OPTN,SOCS4,QRSL1,PIEZO1,GLCCI1,NUDT11,NAA60,GEMIN7,SEPHS2,LZTR1,RACGAP1,PPP3CB,B4GALT4,RLF,RAPGEF6,SNRNP25,RB1,VASP,MED8,VMP1,PPIL2,MEA1,TIMELESS,AHDC1,ALDH18A1,TMEM8A,ABCC1,PREB,TRAPPC9,AACS,MEMO1,KRAS,RTF1,UBE4B,NFATC2IP,LY6E,ARPC1A,ZNF174,PSMC4,GOLGA4,SYNCRIP,PALB2,PRPS2,NIPA1,TIGD2,RNF114,FOXM1,MRPL39,XAB2,SUMO2,DUSP22,COMMD8,RPL11,CSDE1,MDM2,CORO1A,MINPP1,METTL9,POC5,DVL2,GM2A,PSMA8,COQ10B,CPOX,TIGD5,SLC26A6,CYP20A1,PRPF3,TXNL4A,RPSA,SRSF1,DNAJC10,ZNF700,SCAP,PLEKHG4B,TIMM17A,FAU,LTA4H,AP2S1,USP53,INTS2,CTDP1,MIF4GD,CDT1,ARID5A,SUMF1,GGA2,AP3S1,CSNK1A1,RMI1,TFRC,PTPN2,IRF4,GSTK1,NDUFV1,SLC1A4,CWC27,SLC35B4,DDX31,ABCD1,RPAP3,CNTN5,SNX2,ZMYM5,CCDC34,CHCHD6,BSDC1,KPNA4,FBXO41,BIRC5,TFE3,SNAP29,CDCA7L,PKD2,ACADM,CHMP7,SAT2,GCSH,ZNF496,TMEM109,TAP1,NHLRC3,IKBIP,EIF1B,ELMOD2,KIFC1,DBNDD1,CYB5RL,PARPBP,RNASEK,CDC25B,PRADC1,DNMT1,NOL12,ORAI2,USO1,AKT2,NOL8,GNG7,AURKB,MCFD2,SLC25A5,ZFAND5,MAK16,STT3A,TMED10,EIF2D,ITGB1,PTPN7,UQCRH,RRS1,ARRB2,RTN3,ZNF598,SVIP,DDX58,WSB2,PPIB,MUT,GMFG,HLA-E,NDUFA4,MAN2B1,METTL3,CFLAR,NDUFS4,RNF121,MEX3C,KLF16,HDAC7,DAD1,BDH1,GNAI2,ANKHD1,MORC3,TERF2,KCTD20,SEPT8,DCTD,PKM,TOMM40,PATL1,ADSS,SERTAD2,SERF2,ZFP92,NSF,DCK,ERGIC3,ACLY,LPCAT4,VCPIP1,YY1,PPP6R2,MAP3K5,PPP6R3,RNF14,CDK2,ZC3HAV1,SYS1,ZBTB37,URB2,MAGED1,KLHL18,ADPGK,SLC25A44,AP1B1,SDHA,PAIP2,PHC2,CRKL,MOAP1,TERF2IP,CYHR1,ZNF75D,SHC1,UCHL5,NAA35,TMBIM1,CCT2,CDKN2AIP,MKLN1,HMGN4,GALK2,CDC23,SHCBP1,AP4E1,PRDM11,VEZF1,PPP2R5A,ACYP1,STAT1,PPA2,TRIM32,RHEBL1,C1orf112,TCF3,MRI1,BRAP,AGPAT3,MYNN,SDF2L1,SPR,RAB11A,REEP5,FOXO3,MAD2L2,CCDC28A,PIP5K1C,RBM17,MAT2B,PTEN,CENPJ,TAGLN2,OSTC,CREB1,PACS2,NCOA2,SMC4,RNASEH2C,NEK7,NET1,PARP4,TBRG4,ANAPC2,RPL27A,YIF1A,SGSH,HGS,TTLL4,SLC38A7,MFAP1,CCDC69,BRWD3,ESYT2,SKA3,NPHP4,UBE2E2,HNRNPAB,PLXNC1,ST13,TMEM184B,DNAJC24,ZNF107,SLC29A1,KIF2C,AGFG1,SIRT2,FKBP2,USP48,UBQLN2,SNRPD3,CUTC,EDC3,UBLCP1,ZNF804A,RAP1A,THADA,EIF4A3,AP3S2,ATG3,DPYSL2,PPP1R12C,AKR1B1,NDUFB9,JOSD1,RP2,TTC4,TECR,ARID4A,FGFR1OP2,TIMM50,TDP1,DPM1,FOPNL,SLC16A7,WDR82,SLC25A22,STK17B,DHX15,CHAF1A,GEMIN5,COPS6,SASS6,RPS26,PSMC1,SLC12A7,TBC1D12,TM9SF4,ZNF768,MED13L,TIA1,MEF2A,EPHX2,PITHD1,RHBDD1,NFATC3,BANF1,BUD31,ZNF335,YBX1,KNTC1,ACAD8,UBE3C,ZNF189,ALDH9A1,KDELR1,TSTA3,CIC,OXR1,PSMA1,SEPT7,NAP1L1,NSMF,ODF2,EXOC4,KIAA1328,NUP62,PITPNA,NAA20,PTDSS1,MZT2B,PDSS2,C7orf26,TMEM106C,IMMT,ASH1L,CHERP,WDYHV1,PLAGL2,CHKB,IRF3,TWF2,PAIP1,ANKRD28,ANKLE1,FARSA,SAR1A,SCAMP4,APOOL,PDIA6,ACSL5,AZI2,GFER,RAD54B,DAP3,TMEM41A,ZNF317,GADD45B,AKNA,REEP4,CBX4,MIF,KIF3B,GOLPH3L,SH2D3A,CASP6,TOR3A,SRGN,DBF4,MFSD10,SAC3D1,CTNNBL1,YIF1B,CLDND1,TTC17,SLC25A1,GINS1,PAQR6,CSNK1G2,TELO2,ADAM17,HMGN1,NASP,ASPM,PPP1R21,PRKAR1B,SYMPK,TARS,SNRPA,MAPK3,HSPA1B,HLA-B,ATAD2,PLAA,ZNF330,OSBPL8,KBTBD7,PREPL |
| 2.456e-06 | -12.92 | positive regulation of proteolysis involved in cellular protein catabolic process | biological process | GO:1903052 | 122 | 39 | 17256 | 2622 |
ATXN3,SUMO2,NKD2,SIRT2,UBQLN2,CSNK1A1,PSEN1,BCAP31,ANKIB1,FBXO22,DDRGK1,USP5,RAD23A,MDM2,PTEN,RNF19A,SOCS5,PLK1,PLK3,ATP5IF1,LONRF3,RBX1,GBA,EDEM2,PSMC4,HSPA1B,HSPBP1,KEAP1,AXIN1,SOCS4,DVL1,CLU,RNF14,SMURF1,RNF139,PSMC1,CSNK1D,USP13,RNF114 |
| 2.477e-06 | -12.91 | GNF2_BUB3 | MSigDB lists | GNF2_BUB3 | 28 | 15 | 17377 | 2626 |
HNRNPA2B1,PA2G4,HSPB11,SMC3,BANF1,U2SURP,HNRNPF,PTGES3,SNRPG,SNRPD3,TARS,SNRPA,SRSF10,XRCC5,RPA1 |
| 2.488e-06 | -12.90 | GSE37416_12H_VS_24H_F_TULARENSIS_LVS_NEUTROPHIL_DN | MSigDB lists | GSE37416_12H_VS_24H_F_TULARENSIS_LVS_NEUTROPHIL_DN | 173 | 50 | 17377 | 2626 |
MIF,POU3F2,PNISR,ST13,GNPDA1,CAST,HEXB,RRAGC,ASAH1,PDCD7,EIF1B,AP3S1,SAFB2,GNS,SLC31A1,TNFAIP8,RNASEK,MEA1,BRI3,FNIP2,PIK3IP1,DVL2,DRAM2,MOSPD1,SAP30,RAB7A,USP22,OTUD3,CBFA2T2,CHMP2B,TOLLIP,RHEB,EPB41,ZMYM3,DERL1,NAP1L1,SGSH,SMAD2,SNAP29,HIPK2,NSMCE2,COX7A2L,COX5A,ATP6V0C,RBPJ,GPI,PPP6R2,CLN3,HEXA,ATP6V0E1 |
| 2.498e-06 | -12.90 | CBX3 (chromobox 3) | protein interactions | 11335 | 111 | 38 | 17029 | 2761 |
UNK,PTMS,ZNF496,SUZ12,MECP2,CHD1L,CUL1,NSD3,MAD2L2,MIS12,SP100,KMT5C,BANF1,H2AFY,TALDO1,ARL5A,RYBP,WDR1,VHL,MKI67,PCGF6,NFATC2,BRCA1,AURKB,VDAC1,MCM2,TRIM28,POLR2A,CHAF1A,CBX3,ADSS,DSN1,DCK,H3F3A,FAF1,IFI16,ATXN7L2,ADNP2 |
| 2.514e-06 | -12.89 | GSE20715_0H_VS_48H_OZONE_TLR4_KO_LUNG_DN | MSigDB lists | GSE20715_0H_VS_48H_OZONE_TLR4_KO_LUNG_DN | 192 | 54 | 17377 | 2626 |
MIF,HSPH1,PRPF38B,HNRNPAB,ST13,SRSF6,CDK2AP2,GADD45G,SDF2L1,DNAJB1,SLC20A1,MIEN1,STAM,TFRC,SSR1,ERH,PSMD2,PCNA,VMP1,FOXN2,TRA2B,STAT3,LRRC59,PPA1,STRAP,S100A6,FDFT1,METTL1,TK1,ELL2,TMEM39A,PBK,AACS,ERLIN1,MRPL12,LDHA,RRM2,DIDO1,SYVN1,DNAJA1,MCFD2,DDX39A,EIF3A,HINT1,UAP1,CEP55,NFIL3,COX5A,KPNA2,SPCS3,CLU,CCNB2,BYSL,TUBB |
| 2.514e-06 | -12.89 | GSE32986_UNSTIM_VS_GMCSF_AND_CURDLAN_LOWDOSE_STIM_DC_UP | MSigDB lists | GSE32986_UNSTIM_VS_GMCSF_AND_CURDLAN_LOWDOSE_STIM_DC_UP | 192 | 54 | 17377 | 2626 |
CYTIP,TXN,MCM10,SCOC,MRPS15,RRM1,NUF2,CYCS,KIF2C,HAUS2,EBP,ASPHD2,PA2G4,CLIC4,NUP107,NSFL1C,AP2B1,RNASEH2A,CYC1,STAT3,RPRD1B,SYTL3,SNX25,TK1,LACTB,NARF,WDHD1,RRM2,PSMG1,EAF2,PRKRA,VDAC1,EIF4H,PSMB3,SMAP2,CYB5A,GEMIN5,MTHFD2,ATAD2,SURF4,RAD18,ODF2,FAM3C,ACLY,C4orf46,CHEK2,GPI,WDR76,NANP,H3F3A,SASS6,LRP8,ABCA1,RHEBL1 |
| 2.514e-06 | -12.89 | GSE46606_DAY1_VS_DAY3_CD40L_IL2_IL5_STIMULATED_IRF4HIGH_BCELL_UP | MSigDB lists | GSE46606_DAY1_VS_DAY3_CD40L_IL2_IL5_STIMULATED_IRF4HIGH_BCELL_UP | 192 | 54 | 17377 | 2626 |
CCDC93,CTU2,MRPL42,GXYLT1,MRPS2,PHB2,TMEM109,CREBL2,CHKB,MXD4,GGA2,RGS2,MAPK14,TFRC,FBXO5,FERMT3,KRI1,ATP2A2,NAA50,PRADC1,CTDSP2,PABPC1,CFL1,NAGPA,PHF10,MAPRE2,PBXIP1,TSPYL4,NUDT4,TEX10,MAP4K4,MRPL12,MFNG,USP10,PITPNB,EIF4G2,SERP1,MATR3,BTBD1,RPSA,BBS12,CLNS1A,SH3BP5,TSC1,CDKN2AIPNL,HNRNPR,CTBS,KBTBD7,MDH1,YY1,ARRB2,RPS26,IPO4,HIGD2A |
| 2.527e-06 | -12.89 | DNA-templated transcription, termination | biological process | GO:0006353 | 109 | 36 | 17256 | 2622 |
CDC40,SARNP,THOC1,MTERF1,POLR2K,SRSF6,RBM8A,DHX9,SNRPD3,POLR3K,TTF1,PAPOLA,ZNF473,CD3EAP,EIF4A3,SRSF4,POLR1B,CHTOP,CPSF4,ZNRD1,GTF2H2,CSTF1,SRSF11,POLR2L,SNRPB,RNPS1,SLBP,SRSF5,DDX39A,SYMPK,TWISTNB,POLR2A,SRSF1,UBTF,SNRPG,SRSF3 |
| 2.530e-06 | -12.89 | TALDO1 (transaldolase 1) | protein interactions | 6888 | 79 | 30 | 17029 | 2761 |
PTMS,EWSR1,CSRP1,FAM49B,WDR1,UFC1,RAC1,TKT,LDHA,LSM8,ATG2B,BRCA1,PITPNB,PMF1,PCBP1,SCYL2,PARK7,GLOD4,CBX3,TERF2IP,ADSS,CHMP4A,ZHX1,DCK,TALDO1,CDK2,TERF1,POC5,TERF2,LDHB |
| 2.530e-06 | -12.89 | CASP7 (caspase 7) | protein interactions | 840 | 79 | 30 | 17029 | 2761 |
CCT2,MAX,CLSPN,BIRC3,GORASP1,RPS6KA1,CAST,RAC1,XIAP,MEF2A,UBE4B,MEF2D,PSEN1,EIF4H,LYN,BIRC2,CFLAR,GNS,RB1,CDC42,BIRC5,STAT1,CTSA,PTGES3,ROCK1,COPS6,TERF1,CAPN1,DCTN1,SPTAN1 |
| 2.542e-06 | -12.88 | Host Interactions with Influenza Factors | REACTOME pathways | R-HSA-168253 | 42 | 20 | 10287 | 1696 |
TGFB1,NDC1,NUP188,RAE1,NUP54,NUP155,ISG15,NUP205,KPNA4,KPNA1,NUP210,NUP107,NUP62,KPNA2,NUP153,CPSF4,NUP58,NUP85,SEH1L,AAAS |
| 2.562e-06 | -12.87 | breast-carcinoma-ER-PR-positive_carcinoma | COSMIC cancer mutations | breast-carcinoma-ER-PR-positive_carcinoma | 1914 | 354 | 17385 | 2587 |
FGFR1OP,ZBTB10,MAX,TSC2,XIAP,DHX8,USP39,LACTB2,MYEF2,FBXO22,EEF2K,CDKN2C,PSMD1,NOL11,NUP153,CDC25B,TFG,TIPARP,DNMT1,SENP1,USP34,BAK1,CCDC57,ERCC1,NRAS,AKT2,NOL8,USP22,AURKB,CCNF,CBFB,TRIM47,WAS,SMAD2,RAD18,AXIN1,ITGB1,DHTKD1,TRAF5,ARRB2,ZNF598,HDAC2,DDX58,EWSR1,RHOC,PRKAA1,VAV2,TRIO,DLGAP4,RAB23,SLC35B1,NOTCH2,PDCD7,APH1B,PSEN1,CDC73,RTKN,CEP104,MEX3C,ZNRF2,ATIC,HDAC7,MSH2,FBXL7,LUC7L2,SOCS5,WDR1,DHX29,MFNG,USP10,RIT1,ARID1A,ADRB2,ELK1,MAP2K2,RHOB,FAS,XRCC5,ETS2,RBMX,QARS,ERGIC3,PIAS2,FAM83D,USP32,VCPIP1,NDE1,MAP3K5,CDK2,CABLES1,CDKN2A,TRIM41,ZNF296,ABCA3,ATXN3,DNMT3A,IVNS1ABP,RAF1,SUZ12,RAC1,BCL2L1,PRKACA,KTN1,ANKIB1,REPS1,CRKL,CCNA2,FBXL6,SHC1,KDM2A,ZKSCAN1,RALB,GRSF1,UCHL5,ZCCHC2,SOCS6,CDKN1B,TTC3,RNASEH2A,RBM15,ATF2,CDK12,SHOC2,BRD4,ERF,MAP4K4,ELP4,PKMYT1,MEF2D,ERC1,TRIM28,PRDM11,PPP2CA,RAD51C,PPP2R5A,JAK1,STAT1,FUS,B4GALT3,EYA2,POLQ,RHEBL1,PRPF4B,USP13,OTUD5,ZFP91,MANBA,TCF3,BRAP,ATG2B,BLM,IL21R,ETS1,FOXO3,FAM8A1,MAD2L2,HLA-A,NEIL2,WWP2,RFWD3,CAPN2,PDCD10,PTEN,FJX1,AXIN2,PTPN11,LTN1,SLC38A10,UBE3B,CREB1,FBXL19,NCOA2,MSH6,SPTAN1,PDLIM2,PDPK1,TNFAIP3,KAT2A,LRRC1,ZP3,KLF6,MARK2,PICALM,FADD,KEAP1,GPS2,CCDC6,WNT5B,MAPK6,PML,LRPPRC,PPP1R11,RGL1,PARP10,YWHAH,DDB1,NF1,GPBP1L1,TRIM11,MOGS,CSNK2A1,S1PR2,USP48,MAPK14,SEC16A,BIRC2,TET3,FANCL,DLG5,ABL2,RAP1A,CDC42,NT5DC1,IMPAD1,JAZF1,PIK3R2,ETV6,XRCC2,JOSD1,TCEA1,MYBL1,OGG1,CDC37,PLK1,CELSR2,SEPT9,NCK1,APH1A,VHL,LRBA,CDC6,LRP5,BRCA1,PBRM1,KMT2C,USP21,RHEB,MAN2A2,FBXO28,SOCS4,ADAM9,STK11,DVL1,CHEK2,COPS6,FAM208A,NUMB,ZNF564,PARP12,CENPF,LAMTOR3,PCSK7,MEF2A,THRAP3,ASXL2,CRLF3,TTF1,RAPGEF6,ARID1B,NUP205,RB1,XPA,SLC27A4,BCL2,MAML1,UBE3C,ZRANB1,CIC,KRAS,CAND1,GNAS,SDHB,TSC1,MBIP,PCM1,PALB2,YWHAZ,NUP62,TCF12,USP7,PRKAB1,CYLD,TRAF7,ARID2,PMS2,SMARCA4,CHD1,EXT2,USP5,VAV1,MDM2,ZNF770,ABI1,DVL2,POU2AF1,BIRC3,SLC26A6,MBD3,FANCE,EIF3H,USP36,ZNF700,STAT6,STK38,UHRF2,NCOA1,H3F3A,USP11,SMURF1,MAPK1,ABCA1,USP53,SMAD4,INTS2,CMAS,TRIP12,CASP6,SHPRH,CHIC2,CSNK1A1,FZD6,FBXO5,HERC3,GTPBP3,FGFR3,IRF4,CTNNBL1,SS18L1,TTC17,STAT3,FRMD8,TGFB1,PHF20L1,ADAM17,HMGN1,RHOA,ASPM,ARHGEF12,PCGF1,MEN1,TFEB,MAPK3,CACNB1,TRIM26,ATP6V1D,FBXO41,BIRC5,ELMO1,NEIL3,TFE3,DTX4,USP20,RBPJ,HRAS |
| 2.562e-06 | -12.87 | ER-PR-positive_carcinoma | COSMIC cancer mutations | ER-PR-positive_carcinoma | 1914 | 354 | 17385 | 2587 |
FGFR1OP,ZBTB10,MAX,TSC2,XIAP,DHX8,USP39,LACTB2,MYEF2,FBXO22,EEF2K,CDKN2C,PSMD1,NOL11,NUP153,CDC25B,TFG,TIPARP,DNMT1,SENP1,USP34,BAK1,CCDC57,ERCC1,NRAS,AKT2,NOL8,USP22,AURKB,CCNF,CBFB,TRIM47,WAS,SMAD2,RAD18,AXIN1,ITGB1,DHTKD1,TRAF5,ARRB2,ZNF598,HDAC2,DDX58,EWSR1,RHOC,PRKAA1,VAV2,TRIO,DLGAP4,RAB23,SLC35B1,NOTCH2,PDCD7,APH1B,PSEN1,CDC73,RTKN,CEP104,MEX3C,ZNRF2,ATIC,HDAC7,MSH2,FBXL7,LUC7L2,SOCS5,WDR1,DHX29,MFNG,USP10,RIT1,ARID1A,ADRB2,ELK1,MAP2K2,RHOB,FAS,XRCC5,ETS2,RBMX,QARS,ERGIC3,PIAS2,FAM83D,USP32,VCPIP1,NDE1,MAP3K5,CDK2,CABLES1,CDKN2A,TRIM41,ZNF296,ABCA3,ATXN3,DNMT3A,IVNS1ABP,RAF1,SUZ12,RAC1,BCL2L1,PRKACA,KTN1,ANKIB1,REPS1,CRKL,CCNA2,FBXL6,SHC1,KDM2A,ZKSCAN1,RALB,GRSF1,UCHL5,ZCCHC2,SOCS6,CDKN1B,TTC3,RNASEH2A,RBM15,ATF2,CDK12,SHOC2,BRD4,ERF,MAP4K4,ELP4,PKMYT1,MEF2D,ERC1,TRIM28,PRDM11,PPP2CA,RAD51C,PPP2R5A,JAK1,STAT1,FUS,B4GALT3,EYA2,POLQ,RHEBL1,PRPF4B,USP13,OTUD5,ZFP91,MANBA,TCF3,BRAP,ATG2B,BLM,IL21R,ETS1,FOXO3,FAM8A1,MAD2L2,HLA-A,NEIL2,WWP2,RFWD3,CAPN2,PDCD10,PTEN,FJX1,AXIN2,PTPN11,LTN1,SLC38A10,UBE3B,CREB1,FBXL19,NCOA2,MSH6,SPTAN1,PDLIM2,PDPK1,TNFAIP3,KAT2A,LRRC1,ZP3,KLF6,MARK2,PICALM,FADD,KEAP1,GPS2,CCDC6,WNT5B,MAPK6,PML,LRPPRC,PPP1R11,RGL1,PARP10,YWHAH,DDB1,NF1,GPBP1L1,TRIM11,MOGS,CSNK2A1,S1PR2,USP48,MAPK14,SEC16A,BIRC2,TET3,FANCL,DLG5,ABL2,RAP1A,CDC42,NT5DC1,IMPAD1,JAZF1,PIK3R2,ETV6,XRCC2,JOSD1,TCEA1,MYBL1,OGG1,CDC37,PLK1,CELSR2,SEPT9,NCK1,APH1A,VHL,LRBA,CDC6,LRP5,BRCA1,PBRM1,KMT2C,USP21,RHEB,MAN2A2,FBXO28,SOCS4,ADAM9,STK11,DVL1,CHEK2,COPS6,FAM208A,NUMB,ZNF564,PARP12,CENPF,LAMTOR3,PCSK7,MEF2A,THRAP3,ASXL2,CRLF3,TTF1,RAPGEF6,ARID1B,NUP205,RB1,XPA,SLC27A4,BCL2,MAML1,UBE3C,ZRANB1,CIC,KRAS,CAND1,GNAS,SDHB,TSC1,MBIP,PCM1,PALB2,YWHAZ,NUP62,TCF12,USP7,PRKAB1,CYLD,TRAF7,ARID2,PMS2,SMARCA4,CHD1,EXT2,USP5,VAV1,MDM2,ZNF770,ABI1,DVL2,POU2AF1,BIRC3,SLC26A6,MBD3,FANCE,EIF3H,USP36,ZNF700,STAT6,STK38,UHRF2,NCOA1,H3F3A,USP11,SMURF1,MAPK1,ABCA1,USP53,SMAD4,INTS2,CMAS,TRIP12,CASP6,SHPRH,CHIC2,CSNK1A1,FZD6,FBXO5,HERC3,GTPBP3,FGFR3,IRF4,CTNNBL1,SS18L1,TTC17,STAT3,FRMD8,TGFB1,PHF20L1,ADAM17,HMGN1,RHOA,ASPM,ARHGEF12,PCGF1,MEN1,TFEB,MAPK3,CACNB1,TRIM26,ATP6V1D,FBXO41,BIRC5,ELMO1,NEIL3,TFE3,DTX4,USP20,RBPJ,HRAS |
| 2.588e-06 | -12.86 | Ribosome | KEGG pathways | hsa03010 | 134 | 43 | 7161 | 1149 |
RPS15,RPS2,MRPL9,RPLP2,MRPS2,MRPS15,RPL15,MRPL19,RPL11,RPL23A,RPL17,MRPL34,RPL19,MRPL11,MRPL21,RPL22L1,MRPL32,RPL29,RPL35,RPS10,RPL38,RPL8,MRPL12,RPL6,RPS24,MRPS10,MRPL16,MRPS14,RPL27A,RPS9,RPSA,RPL36,RPL37,MRPL2,RPL32,RPS27A,RPS14,MRPL27,RPLP1,FAU,MRPL13,MRPL3,RPS26 |
| 2.588e-06 | -12.86 | Ribosome | KEGG pathways | ko03010 | 134 | 43 | 7161 | 1149 |
RPS15,RPS2,MRPL9,RPLP2,MRPS2,MRPS15,RPL15,MRPL19,RPL11,RPL23A,RPL17,MRPL34,RPL19,MRPL11,MRPL21,RPL22L1,MRPL32,RPL29,RPL35,RPL8,MRPL12,RPS10,RPL6,RPL38,MRPS10,RPS24,MRPL16,RPL27A,MRPS14,RPS9,RPSA,RPL36,RPL37,MRPL2,RPL32,RPS27A,RPS14,MRPL27,RPLP1,FAU,MRPL13,RPS26,MRPL3 |
| 2.597e-06 | -12.86 | REACTOME_DNA_REPAIR | MSigDB lists | REACTOME_DNA_REPAIR | 101 | 34 | 17377 | 2626 |
POLR2K,XAB2,MAD2L2,MBD4,FANCL,RPA2,PCNA,RAD23B,XPA,TCEA1,GTF2H2,OGG1,TDP1,ERCC1,POLR2I,RFC3,POLR2L,POLR2G,PRKDC,POLR2D,BRCA1,MPG,FANCE,RFC2,POLR2A,XRCC5,RPA1,POLR2J,POLE,PALB2,RPS27A,H2AFX,XRCC4,DDB1 |
| 2.609e-06 | -12.86 | HALLMARK_MTORC1_SIGNALING | MSigDB lists | HALLMARK_MTORC1_SIGNALING | 197 | 55 | 17377 | 2626 |
UBE2D3,IMMT,PDAP1,FAM129A,ACTR3,SLC2A1,TMEM97,SDF2L1,FKBP2,GGA2,TFRC,PNO1,NUP205,SSR1,EBP,SEC11A,RPN1,ADD3,EIF2S2,SLC1A4,ATP2A2,UCHL5,CORO1A,TCEA1,PPA1,PLK1,IFRD1,ELOVL5,USO1,BTG2,ACSL3,ABCF2,LDHA,RRM2,PSMG1,RIT1,PITPNB,TOMM40,CCNF,RAB1A,MCM2,DDX39A,SERP1,PRDX1,PSMC4,RDH11,RPA1,EPRS,HSPA4,MTHFD2,ATP6V1D,NFIL3,ACLY,GPI,LTA4H |
| 2.623e-06 | -12.85 | GSE2706_UNSTIM_VS_8H_LPS_AND_R848_DC_UP | MSigDB lists | GSE2706_UNSTIM_VS_8H_LPS_AND_R848_DC_UP | 178 | 51 | 17377 | 2626 |
SLC12A7,GNPDA1,KLHL21,MUM1,UFC1,CERK,SMARCA4,HAUS4,NHLRC3,TWF2,ELMOD2,JMY,PHC2,GSTK1,TBC1D22A,TBC1D14,PHF14,MEA1,AP1M1,TTC3,MRPL48,MRPL11,RNF135,CNPY3,NUP85,MSH6,TRIM14,CAMK2G,CARS2,FAM118B,HEBP2,DNAJC9,MEF2D,DCLRE1C,ICMT,SHCBP1,TXNL4A,PRPSAP1,HAGH,CBFB,RPA1,PON2,EPRS,VPS26B,CCDC14,CDCA7L,LPCAT4,H2AFX,IARS2,ACAT1,DTD1 |
| 2.673e-06 | -12.83 | ATP1A1 (ATPase Na+/K+ transporting subunit alpha 1) | protein interactions | 476 | 128 | 42 | 17029 | 2761 |
COX15,CYLD,NDUFS1,ADD1,SDHA,NDUFS4,RPN1,NDUFV1,ZNRF2,HUWE1,AHSA1,ZNF746,HADHB,CRY2,CYC1,MRPL40,TECR,LMAN1,ATF2,ATP6V0D1,CFL1,TMED2,STAU1,PPT1,CUL3,VDAC2,SSR2,ADRB2,VDAC1,RAB1A,CCT8,NCDN,MAPK3,HGS,DDOST,PKD2,MBOAT1,ACADM,CLN3,CDK2,ECPAS,MAPK1 |
| 2.685e-06 | -12.83 | FURUKAWA_DUSP6_TARGETS_PCI35_DN | MSigDB lists | FURUKAWA_DUSP6_TARGETS_PCI35_DN | 68 | 26 | 17377 | 2626 |
HJURP,PBK,CENPF,TPX2,RRM1,RACGAP1,NUSAP1,EBNA1BP2,KIF2C,AURKB,WDR5,BLM,CCNB1,SHCBP1,NCAPG,KIF11,ETS1,PRIM1,DTL,CCNA2,MCM5,CEP55,PRC1,CCNB2,PDLIM2,POLQ |
| 2.691e-06 | -12.83 | APLNR (apelin receptor) | protein interactions | 187 | 95 | 34 | 17029 | 2761 |
INTS2,NDC1,MTX3,C19orf25,DNAAF5,SLC4A2,SLC29A1,XPO7,TMEM161B,PDXDC1,XPR1,EBP,NUS1,THADA,INTS1,ARF5,BDH1,PDS5B,INTS12,ABCD1,OGG1,ELOVL5,BTAF1,TMEM126B,MTX1,SFXN5,JAK1,AGPAT2,EXOC4,NR2F2,CHPT1,ECPAS,MZT2B,GPR89B |
| 2.691e-06 | -12.83 | ERG (ERG, ETS transcription factor) | protein interactions | 2078 | 95 | 34 | 17029 | 2761 |
HNRNPAB,TRIP12,SF3B1,HNRNPUL2,TOP2B,LANCL1,PCBP1,APP,SF3B2,HNRNPA2B1,HUWE1,FBL,HNRNPM,CDC5L,SPTAN1,SNRNP200,PRKDC,HNRNPF,CUL3,ILF3,DNAJA1,MATR3,POLR2A,DDX23,XRCC5,HSPA4,ETS2,HNRNPH3,ACTB,DDX5,ATP5F1A,XRCC4,HNRNPDL,TUBB |
| 2.692e-06 | -12.83 | JAIN_NFKB_SIGNALING | MSigDB lists | JAIN_NFKB_SIGNALING | 72 | 27 | 17377 | 2626 |
GBA,PSMG1,PAWR,SLC29A1,XPO7,PMVK,SYMPK,HDDC2,CLNS1A,HSPA1B,BCAT2,CBX3,TFAP4,ALG3,TPD52L2,DECR1,NAP1L1,PTPN7,NOC2L,TAP2,TICAM1,PREPL,FBL,SSSCA1,RNF5,DDX42,DCTN1 |
| 2.698e-06 | -12.82 | mitochondrial translational elongation | biological process | GO:0070125 | 88 | 31 | 17256 | 2622 |
MRPL9,MRPL42,MRPS2,MRPS15,MRPL39,MRPL43,TUFM,MRPL12,MRPS26,MRPS10,MRPL16,MRPS14,GFM2,MRPL19,MRPL50,MRPL2,DAP3,MRPL55,CHCHD1,MRPL27,MRPL34,MRPS27,MRPL54,MRPL48,MRPL40,MRPL21,MRPL11,MRPL13,MRPL3,MRPL32,MRPL57 |
| 2.737e-06 | -12.81 | peptidase complex | cellular component | GO:1905368 | 90 | 31 | 18223 | 2701 |
TXNL1,UBQLN4,PSMA8,UBXN1,PSMB7,PSMA1,SUPT20H,TAF6L,USP22,PSMD9,PSMB9,PSMB3,PSMC4,RAD23A,SEC11A,PSMD2,PSMA6,PSMD1,IDE,PSMD8,PSMD3,UCHL5,RAD23B,SPCS3,TAF12,UBE3C,TAF6,ECPAS,PSMC1,SGF29,HTRA2 |
| 2.751e-06 | -12.80 | GSE17721_POLYIC_VS_CPG_8H_BMDC_DN | MSigDB lists | GSE17721_POLYIC_VS_CPG_8H_BMDC_DN | 183 | 52 | 17377 | 2626 |
SRM,DNAJC2,SMAP1,RRP15,MRPS2,SRSF6,C16orf87,STARD7,NCKAP1,OAT,PITHD1,POLR3K,RHBDD1,FBXO22,ATP2A2,IARS,UTP18,TAGLN2,TSHZ1,PPIF,FTL,ADAM17,ZFP64,GABPA,TEX10,GTPBP4,FAM133B,MCFD2,LUC7L,EIF4H,ARPC1A,GFER,TSR2,NMT2,CLNS1A,UTP20,RAB18,KPNA1,TTC13,SYNCRIP,TMED10,TPP2,RBMX,ERGIC3,WDR4,ITGB1,FAM122A,SSNA1,PREPL,NGLY1,PSMC1,CPEB2 |
| 2.761e-06 | -12.80 | M/G1 Transition | REACTOME pathways | R-HSA-68874 | 86 | 32 | 10287 | 1696 |
POLA2,MCM10,CDT1,DBF4,ORC1,PSMD9,RPA2,PSMD2,PSMD1,PSMA6,MCM5,ORC3,PRIM2,PSMA8,PSMB7,E2F3,PSMA1,CDC6,MCM2,PSMB9,PSMB3,PRIM1,RPA1,PSMC4,POLE,RPS27A,PSMD3,PSMD8,E2F1,E2F2,CDK2,PSMC1 |
| 2.761e-06 | -12.80 | DNA Replication Pre-Initiation | REACTOME pathways | R-HSA-69002 | 86 | 32 | 10287 | 1696 |
POLA2,MCM10,CDT1,DBF4,ORC1,PSMD9,RPA2,PSMD2,PSMD1,PSMA6,MCM5,ORC3,PRIM2,PSMA8,PSMB7,E2F3,PSMA1,CDC6,MCM2,PSMB9,PSMB3,PRIM1,RPA1,PSMC4,POLE,RPS27A,PSMD3,PSMD8,E2F1,E2F2,CDK2,PSMC1 |
| 2.788e-06 | -12.79 | GO_PROTEIN_METHYLATION | MSigDB lists | GO_PROTEIN_METHYLATION | 97 | 33 | 17377 | 2626 |
ASH1L,SUZ12,MECP2,CXXC1,EZH1,RAB6A,SNRPD3,WDR5,TET3,IRF4,SUV39H2,PRDM4,ZNF335,CTR9,FBL,ARID4A,CARM1,HEMK1,SNRPB,BTG2,EHMT1,RTF1,WDR82,MEN1,PRMT2,ICMT,KDM3A,DOT1L,SETD3,CAMKMT,OGT,PRMT7,BEND3 |
| 2.788e-06 | -12.79 | PUJANA_BREAST_CANCER_LIT_INT_NETWORK | MSigDB lists | PUJANA_BREAST_CANCER_LIT_INT_NETWORK | 97 | 33 | 17377 | 2626 |
BCCIP,CLSPN,DHX9,BRAP,SMARCA4,CSNK2A1,BLM,CCNB1,RPA2,RB1,MDM2,CCNA2,MSH2,MSH6,TERF2,PLK1,PLK3,PRKDC,ELK1,RFC2,RPA1,PEX5,JAK1,E2F4,H2AFX,E2F1,STAT1,KPNA2,CHEK2,RBBP4,CDK2,TERF1,HDAC2 |
| 2.788e-06 | -12.79 | GO_PROTEIN_ALKYLATION | MSigDB lists | GO_PROTEIN_ALKYLATION | 97 | 33 | 17377 | 2626 |
ASH1L,CXXC1,SUZ12,MECP2,RAB6A,EZH1,SNRPD3,WDR5,TET3,IRF4,SUV39H2,PRDM4,ZNF335,CTR9,FBL,ARID4A,CARM1,HEMK1,SNRPB,BTG2,EHMT1,RTF1,WDR82,PRMT2,MEN1,ICMT,KDM3A,DOT1L,SETD3,CAMKMT,OGT,PRMT7,BEND3 |
| 2.826e-06 | -12.78 | GO_MEMBRANE_BUDDING | MSigDB lists | GO_MEMBRANE_BUDDING | 110 | 36 | 17377 | 2626 |
CHMP2A,PDCD6IP,GORASP1,ARF1,SEC16A,ANKRD28,CD59,SEC24C,PPP6C,AP2B1,TFG,LMAN1,LRSAM1,PPP6R1,TMED2,PREB,TRAPPC9,USO1,CUL3,CHMP2B,RAB1A,MCFD2,PICALM,SEC31A,CHMP4A,SEC23IP,GOLGA2,TMED10,NSF,MYO18A,CHMP4B,VPS4A,PPP6R3,CHMP7,AP2S1,CSNK1D |
| 2.828e-06 | -12.78 | HDAC2 (histone deacetylase 2) | protein interactions | 3066 | 330 | 86 | 17029 | 2761 |
UBE2E2,TSC22D3,SUZ12,SUMO2,CSNK2A1,SMARCA4,RCOR3,PARK7,MXD1,PHC2,SAP130,PA2G4,CCNA2,MTA1,SMARCE1,DNMT1,SAP30L,SENP1,ARID4A,RLIM,SAP30,PLK1,SP3,VHL,EHMT1,PCGF6,DDX20,MIER2,BRCA1,DNAJA1,MBD3,FKBP3,ZMYM3,DDX17,BRMS1,HSPA4,SMAD2,RBL1,CHD3,MAFK,CRCP,ARRB2,SINHCAF,HDAC2,NCOR2,UNK,EWSR1,PHB2,C16orf87,TOP2B,WDR5,HMG20A,TFAP4,RB1,SMC3,HUWE1,HDAC7,PPP1R8,MBD2,BANF1,PRDM4,H2AFY,SS18L1,CREB1,STAT3,PHF20L1,IFRD1,FOXK1,MTA2,MIER1,RCOR1,FAM50B,MEN1,APPL1,KPNA1,PML,DDX5,CABIN1,RUVBL2,RBPJ,PPP6R3,YY1,RBBP4,SNRNP70,TAF6,DDB1 |
| 2.871e-06 | -12.76 | GSE5679_CTRL_VS_RARA_AGONIST_AM580_TREATED_DC_UP | MSigDB lists | GSE5679_CTRL_VS_RARA_AGONIST_AM580_TREATED_DC_UP | 188 | 53 | 17377 | 2626 |
MRPL42,PRKCSH,SNX15,CDCA3,OLA1,DNAJC24,KIF23,GTF3A,KIF2C,PMF1,BCL2L1,POLR3K,FBXO5,CCNA2,CTNNBL1,AHSA1,MCM5,RAB35,TPST1,SEPT11,LRRC59,EIF3L,PSRC1,ASPM,MKI67,TBRG4,SLBP,NUSAP1,BRCA1,GAR1,SHCBP1,DDX39A,SNRPA,ASF1B,RAD54B,PRIM1,BOLA3,MTHFD2,KIF18B,CHCHD1,NEIL3,MRPL27,H2AFX,NUP62,KPNA2,ANP32E,BEND3,SPCS3,CCNB2,MRPL3,TUBB,GPATCH4,GCSH |
| 2.871e-06 | -12.76 | GSE15330_WT_VS_IKAROS_KO_GRANULOCYTE_MONOCYTE_PROGENITOR_DN | MSigDB lists | GSE15330_WT_VS_IKAROS_KO_GRANULOCYTE_MONOCYTE_PROGENITOR_DN | 188 | 53 | 17377 | 2626 |
FOXM1,ANKH,TRAK1,FLOT1,PLAGL2,EPN1,KLF13,B4GALT1,RACGAP1,COMMD5,STMN1,MAPK14,PRNP,APLP2,NEK6,INPP5A,CDKN1B,ANXA5,KIFAP3,AFF1,MARCH2,MYBL1,RPRD1B,GM2A,KCNAB2,TMX1,MYO5A,KDELR1,CYTH1,HEMK1,BIRC3,PGS1,LRBA,GBA,EMP3,CDC6,TANC1,EDEM2,KLF6,PLEKHF2,NECAP2,TAB2,SNAP29,NFIL3,RBMS1,FAM122A,ADAM9,PSAP,FBXL3,PLOD3,ARRB2,YWHAH,VPS29 |
| 2.871e-06 | -12.76 | GSE28726_NAIVE_VS_ACTIVATED_NKTCELL_DN | MSigDB lists | GSE28726_NAIVE_VS_ACTIVATED_NKTCELL_DN | 188 | 53 | 17377 | 2626 |
RHOG,CHMP2A,CYTIP,FEZ2,HNRNPAB,IVNS1ABP,URB2,DYNLL1,SRGN,ADO,AP3M2,PLAGL2,CYCS,ARF1,FKBP2,SAFB2,PSMD9,PRPF18,FANCI,PNO1,CFLAR,PSMD1,TXLNA,ATP6V0A2,SS18L1,MAP3K14,AHCYL1,LPCAT1,ANKLE2,SP3,IFRD1,ACP2,MKLN1,PGGT1B,GABPA,WDR1,HNRNPF,EZR,UTP3,EIF4G2,RAB22A,FADD,PPP2CA,MTHFD2,SYNCRIP,UAP1,CCDC6,PRDX3,HPS5,SNRPG,RRS1,PGAM1,CD81 |
| 2.907e-06 | -12.75 | GO_MITOCHONDRIAL_MATRIX | MSigDB lists | GO_MITOCHONDRIAL_MATRIX | 379 | 91 | 17377 | 2626 |
KARS,LYRM4,ATXN3,SUCLG1,MRPS15,MRPL39,MDH2,MCCC1,GLUD1,BCL2L1,OAT,MRPL19,PARK7,BCAT2,FLAD1,DECR1,PDK2,SHC1,GOT2,GRSF1,MRPL34,CS,HADHB,SUCLG2,TOP1MT,LRRC59,MRPL32,PPIF,IDH3A,MRPL12,MRPL43,VDAC2,MCL1,BRCA1,NDUFA7,OGDH,VDAC1,SLC25A5,MRPS14,POLG2,PDHX,MRPL2,DAP3,MRPL55,FASTK,PRDX5,MRPL27,PPA2,IARS2,MLYCD,DHTKD1,RNASEL,MRPL13,PITRM1,MRPL9,NDUFS1,MUT,MRPL42,MRPS2,MRPS26,GFM2,NDUFS7,GSTK1,BDH1,NDUFS8,MRPL40,MRPL48,ACAD8,CREB1,MRPL11,MRPL21,NSUN4,CARS2,DDX28,TUFM,MRPL16,MPG,HAGH,AKAP1,MTHFD2,PRDX3,QARS,PARG,LRPPRC,ACAT1,ACADM,IDH3B,PDSS2,ACSF2,MRPL3,GCSH |
| 2.935e-06 | -12.74 | GPI (glucose-6-phosphate isomerase) | protein interactions | 2821 | 68 | 27 | 17029 | 2761 |
ZNF207,PDCD6IP,WDR1,MRPL12,TKT,CSNK2A1,BRCA1,NANS,LACTB2,SND1,PEF1,CPNE3,ISG15,SDHB,PA2G4,PCNA,CCP110,HUWE1,GOT2,PPME1,CS,ANXA5,FUS,GPI,SPRYD4,CDK2,PPA1 |
| 2.935e-06 | -12.74 | FAU (FAU, ubiquitin like and ribosomal protein S30 fusion) | protein interactions | 2197 | 68 | 27 | 17029 | 2761 |
RPS15,RPS2,CYLD,DYNLL1,CUL3,CUL1,RPS24,PRPF3,BRCA1,RPL27A,RPS9,RPSA,EIF3A,PNO1,RPL11,RPL23A,CAND1,PA2G4,EIF2S2,RPL32,AHSA1,PRPF4,COPS6,CD81,RPS26,BYSL,SPTAN1 |
| 2.946e-06 | -12.73 | TXN (thioredoxin) | protein interactions | 7295 | 120 | 40 | 17029 | 2761 |
UNK,COX15,EWSR1,RAE1,TOR1AIP1,CUL1,FKBP2,PARK7,FKBP1A,PTEN,SIAH1,UCHL5,ATIC,TAGLN2,AHCYL1,IMPA2,TMX1,SRPK2,UBQLN4,WDR1,VHL,UBE2V1,DNAJA1,PCGF1,VDAC1,MCM2,RAB1A,GFER,MAP2K2,PRDX1,GLOD4,GEMIN5,PDCD6,HINT1,SYNCRIP,COPS6,MAP3K5,CDK2,PGAM1,SSSCA1 |
| 2.946e-06 | -12.73 | DERL1 (derlin 1) | protein interactions | 79139 | 120 | 40 | 17029 | 2761 |
MDH2,APP,BCAP31,HLA-A,RNF103,LMNA,RPN1,PSMD2,PSMD1,GART,PSMA6,ATP2A2,HUWE1,ANP32A,YIF1B,AHCY,CLN6,RNF5,PSMB7,PSMA1,SYVN1,ESYT1,MCM2,HSPA1B,RPA1,CAND1,XRCC5,DERL1,DDOST,PSMD3,ACLY,SEL1L,MBOAT1,XRCC3,DDX5,RUVBL2,NGLY1,DDB1,ESYT2,SVIP |
| 2.966e-06 | -12.73 | mRNA 3'-end processing | biological process | GO:0031124 | 76 | 28 | 17256 | 2622 |
SRSF11,CDC40,SARNP,THOC1,SRSF6,RBM8A,RNPS1,POLR2D,SLBP,SRSF5,DDX39A,SYMPK,CDC73,APP,SRSF1,PAPOLA,PAF1,ZNF473,EIF4A3,GRSF1,SRSF4,SRSF3,CPSF4,AHCYL1,CHTOP,ZC3H3,PABPC1,CSTF1 |
| 2.966e-06 | -12.73 | regulation of sister chromatid segregation | biological process | GO:0033045 | 76 | 28 | 17256 | 2622 |
PLK1,ZNF207,CDT1,CENPF,PTTG1,CUL3,RMI2,CTCF,CDC6,CCNB1,CDC23,BECN1,MAD2L2,RB1,NEK6,CDC27,NSMCE2,CDCA5,AXIN2,H2AFY,XRCC3,GEN1,UBE2C,SLF1,ESPL1,SLF2,ANAPC4,TACC3 |
| 2.976e-06 | -12.73 | MATTIOLI_MGUS_VS_PCL | MSigDB lists | MATTIOLI_MGUS_VS_PCL | 93 | 32 | 17377 | 2626 |
HECA,NASP,WDR18,ACTR3,HNRNPF,TBRG4,CSNK2A1,SMARCA4,NUSAP1,ESYT1,SNRPD3,MCM2,CDC73,CPNE3,FADD,SAC3D1,SRSF1,PSMC4,AKAP1,PCNA,NUP210,PRDX3,INTS7,MCM5,GADD45B,LPCAT4,RPLP1,NUP62,CORO1A,TUBB,MSH6,SAP30 |
| 2.976e-06 | -12.72 | MRPS16 (mitochondrial ribosomal protein S16) | protein interactions | 51021 | 33 | 17 | 17029 | 2761 |
MRPS2,COQ8A,MRPS26,FAM136A,FAM50B,ZP3,SLC25A5,CAND1,COQ4,HNRNPR,MPV17,MRPS27,DUSP11,TRMT10B,RRS1,HNRNPDL,PSMC1 |
| 2.978e-06 | -12.72 | histone lysine methylation | biological process | GO:0034968 | 68 | 26 | 17256 | 2622 |
ASH1L,KMT2E,SUZ12,CXXC1,EHMT1,NSD3,WDR82,RTF1,EZH1,WDR5,KMT2C,MEN1,RLF,KDM3A,DOT1L,TET3,SUV39H2,KMT5C,KMT5A,SETD3,OGT,ZNF335,KMT2B,CTR9,BEND3,ARID4A |
| 2.984e-06 | -12.72 | GSE360_L_DONOVANI_VS_B_MALAYI_LOW_DOSE_DC_DN | MSigDB lists | GSE360_L_DONOVANI_VS_B_MALAYI_LOW_DOSE_DC_DN | 193 | 54 | 17377 | 2626 |
SNX27,H2AFZ,MAX,HLA-E,UBXN1,TRIO,TKT,SLC25A12,AP1B1,PIP4K2A,HDDC2,CNOT3,DST,VAV1,SEC11A,GART,NDUFV1,PCNA,AHCY,FAM3A,CNPY3,OGG1,CTDSP2,IMPA2,PCBP2,MED22,AMPD2,ERCC1,CYFIP1,DDX28,SNRNP200,MLEC,NASP,KAT2A,CSRP1,ERF,TACC1,WDR1,RPL6,ESYT1,DDX39A,STX16,SOCS7,RDH11,HMGN2,SDHB,STK38,OGT,MEGF9,SRSF3,PREPL,HEXA,LTA4H,ZC3HAV1 |
| 2.985e-06 | -12.72 | GSE17974_1.5H_VS_72H_IL4_AND_ANTI_IL12_ACT_CD4_TCELL_DN | MSigDB lists | GSE17974_1.5H_VS_72H_IL4_AND_ANTI_IL12_ACT_CD4_TCELL_DN | 174 | 50 | 17377 | 2626 |
SKA3,MRPS15,DHPS,CENPF,UCK2,ACAP1,RAB23,HAUS4,PM20D2,TWF2,POLR3K,KTN1,MAD2L2,CDK5,DLG5,CYHR1,HOMER1,SUV39H2,ARPC5,ATIC,SRI,CENPM,ALDH18A1,ORC3,MRPL11,C12orf75,DVL2,RNF5,CARM1,HPDL,MAPKAPK3,RAB7A,LRRC1,STYXL1,ASF1B,RDH11,ANKZF1,RAD51C,TIMM13,NRM,DBI,ACLY,PTAR1,ACAT1,DHTKD1,ACADM,RUVBL2,WDR76,CDK2,POLQ |
| 3.008e-06 | -12.71 | SNRPF (small nuclear ribonucleoprotein polypeptide F) | protein interactions | 6636 | 150 | 47 | 17029 | 2761 |
MAPRE1,CDC40,CYLD,GPBP1L1,XAB2,SF3B1,RBM8A,LAGE3,OLA1,SNRPD3,PDCD7,SRRT,SEC24C,CMTR2,EFTUD2,RAD23B,GEMIN6,GPATCH1,TAGLN2,AQR,GEMIN4,OGG1,SNRNP200,SNRPB,PPIE,CUL3,CRNKL1,LSM8,DDX20,KRAS,PRPF3,SRSF5,TXNL4A,SF3A2,SNRPA,CLNS1A,DDX23,CAND1,GEMIN5,LSM6,YWHAZ,PRPF4,SNRPG,SNRNP70,CDK2,IGBP1,COIL |
| 3.016e-06 | -12.71 | SUMO2 (small ubiquitin-like modifier 2) | protein interactions | 6613 | 208 | 60 | 17029 | 2761 |
USP7,ZNF496,EWSR1,NOP2,SUMO2,TOP2B,BLM,UBE2I,PARN,RCOR3,CMTM6,ZBTB21,BABAM2,SP100,MTA1,ATIC,TANK,MSH2,NUP153,MAST2,TP53BP2,AHCYL1,SENP1,HP1BP3,PRKDC,MTA2,ZMYM5,TEX10,HNRNPF,MKI67,CUL3,RCOR1,TOPORS,EXOSC9,RANGAP1,BRCA1,TRIM28,CHAF1A,XRCC5,ZMYM3,SUPT16H,DDX17,AHNAK,TRIM26,ZHX1,CHD3,HIPK2,PML,PIAS2,BAZ1B,CTSA,PSAP,USP11,RBBP4,IGBP1,ZMAT3,TUBB,HDAC2,SSSCA1,SSRP1 |
| 3.025e-06 | -12.71 | ATP5F1A (ATP synthase F1 subunit alpha) | protein interactions | 498 | 172 | 52 | 17029 | 2761 |
UNK,IMMT,CYLD,MDH2,FLOT1,MYH9,CUL1,CSNK2A1,CHCHD2,ATP5F1B,ATP6V1B2,ATP5PF,APP,CDC73,NDUFS4,WWP2,RPN1,PTEN,HUWE1,MCM5,ZNF746,ZFYVE27,RPN2,TARDBP,CYC1,LMAN1,ATP6V0D1,PABPC1,ABCC1,STAU1,PTPN18,PPT1,VDAC2,CUL3,ADRB2,ATP5MF,MCM2,VDAC1,MATR3,NCDN,ECH1,ISG15,STOML2,CAND1,IDE,YWHAZ,XRCC3,MBOAT1,FUS,ATP5F1A,CDK2,CD81 |
| 3.040e-06 | -12.70 | human chr1q22 | chromosome location | human chr1q22 | 61 | 20 | 26185 | 2809 |
PAQR6,UBQLN4,ASH1L,SCAMP3,GBA,SSR2,MEF2D,PMF1,RIT1,MTX1,KRTCAP2,SLC25A44,SLC50A1,GLMP,YY1AP1,LMNA,DAP3,ARHGEF2,NAXE,KHDC4 |
| 3.042e-06 | -12.70 | CDC73 (cell division cycle 73) | protein interactions | 79577 | 259 | 71 | 17029 | 2761 |
KARS,TOMM20,DNMT3A,MRPS15,MYH9,CUL1,CNTROB,PCBP1,RPL11,RAB8A,PCNA,RPN2,TCEA1,PDIA6,CFL1,CDC5L,CCT2,POLR2G,HNRNPF,AURKB,DNAJA1,RAB1A,KMT2C,RPSA,ARF4,PAF1,HSPA4,RPS27A,ITGB1,UHRF2,CHEK2,MIF,ANXA6,SCAMP3,ATP5F1B,ARF1,LANCL1,AP3S1,PITHD1,TFRC,GTF2F1,FBXO3,PSMD2,RPN1,PTPN11,CTR9,TAGLN2,CPSF4,PPA1,EEF1D,PRKDC,TOP3A,LDHA,RPS10,RTF1,KRAS,PKM,CCT8,PRDX1,POLR2A,CAND1,FBXO21,GNA12,EPRS,C1orf131,GOLGA2,IMPDH1,YWHAZ,ATP5F1A,RUVBL2,FAF1 |
| 3.071e-06 | -12.69 | V$SP1_Q4_01 | MSigDB lists | V$SP1_Q4_01 | 232 | 62 | 17377 | 2626 |
POU3F2,RHOG,UGP2,PHF23,ZNF768,AP3M2,KLF13,MXD4,DCUN1D4,STMN1,CHKA,PTPN2,APLP2,KDM2A,ATP2A2,SNX18,UTP18,ARHGEF1,CNPY4,CS,TIMELESS,ANP32A,CTR9,GLTP,UPF2,CREB1,SMARCE1,SENP1,CAMK2G,CGGBP1,CDC37,NASP,KAT2A,SNX2,DRAP1,LYRM1,LDB1,SLBP,RTF1,WDR81,CADM1,PRKRA,ELK1,ERC1,TRIM28,RAB2B,EPB41,SH3BP5,MRPL2,ZNF282,FNTA,AHNAK,CORO1C,OAZ2,BCL7C,PITPNA,TAF6,CSNK1D,ALS2,DDB1,SMARCD1,SNAPIN |
| 3.099e-06 | -12.68 | positive regulation of cellular protein catabolic process | biological process | GO:1903364 | 141 | 43 | 17256 | 2622 |
ATXN3,SUMO2,NKD2,SIRT2,UBQLN2,CSNK1A1,PSEN1,BCAP31,ANKIB1,FBXO22,DDRGK1,USP5,RAD23A,MDM2,PTEN,RNF19A,SOCS5,PLK1,PLK3,ATP5IF1,TNFAIP3,LONRF3,RBX1,GBA,EZR,PTTG1IP,EDEM2,PSMC4,HSPA1B,HSPBP1,KEAP1,AXIN1,SOCS4,DVL1,CLU,CD81,SMURF1,RNF14,PSMC1,RNF139,CSNK1D,USP13,RNF114 |
| 3.126e-06 | -12.68 | GNF2_PPP6C | MSigDB lists | GNF2_PPP6C | 35 | 17 | 17377 | 2626 |
UBE2D3,ZNF207,MAPRE1,EIF3D,SUMO2,ACTR3,PSMA1,SNRPD3,KCMF1,PAPOLA,DAP3,PPP6C,RBM3,SRSF3,YY1,CCDC59,SMNDC1 |
| 3.134e-06 | -12.67 | KRIGE_RESPONSE_TO_TOSEDOSTAT_24HR_UP | MSigDB lists | KRIGE_RESPONSE_TO_TOSEDOSTAT_24HR_UP | 677 | 146 | 17377 | 2626 |
HECA,DCAF15,TSC22D3,FAM129A,TAP1,XIAP,PTP4A3,AGFG1,NHLRC3,MAP1LC3B,RBM4,SLC25A37,ASPHD2,PRNP,ZER1,DLG5,C18orf32,DPYSL2,EIF5,OGG1,ARID4A,MLST8,USP34,SP3,USO1,RHOBTB3,TRIM8,EXOSC6,KLF10,BAZ2A,MCL1,STX16,RAB2B,TRIM4,RPL37,MID1IP1,PTER,OGT,PTPDC1,DCAF5,PDCD4,NUMB,WSB2,HLA-E,TATDN3,SDC2,MEF2A,B4GALT4,RGS2,APH1B,ZNF518A,RHBDD1,GNS,KLHL5,ABHD2,IFRD1,TSPAN31,RIT1,ZNF174,OSBPL11,MTHFD2,GOLGA2,NFIL3,RUFY3,NDE1,N4BP2L2,TCF12,CYLD,NQO1,IVNS1ABP,CAST,PLAGL2,CREBL2,CHKB,GGPS1,MXD1,CCDC50,SP100,LPIN2,EFCAB11,APOOL,FAM3A,RBM15,GCC1,SCYL3,POC5,TIMP2,ATXN1,MTMR6,GORAB,AZI2,TAZ,DNAJC10,JAK1,HIPK2,PPA2,ZNF436,SEL1L,NCOA1,CENPBD1,AKNA,MAPK1,CBX4,RAD51D,OTUD5,GNE,FLOT1,VPS45,BRAP,LETMD1,ETS1,CSNK1A1,SCYL2,POFUT1,DNAJB9,HLA-A,SLC25A36,CAPN2,CLIC4,CTSS,SLC1A4,TANK,SGCB,MYO5A,SAMD4B,NASP,DENND1B,ZMYM5,RAB3IP,PNPLA8,PRMT2,HAGH,SH3GLB1,BSDC1,ZNF862,NEK1,TFE3,CTBS,PML,CCDC69,PKD2,MBD6,RPS6KC1,CPEB2,IFI16,ZSWIM6 |
| 3.136e-06 | -12.67 | GSE7460_CTRL_VS_TGFB_TREATED_ACT_TREG_UP | MSigDB lists | GSE7460_CTRL_VS_TGFB_TREATED_ACT_TREG_UP | 179 | 51 | 17377 | 2626 |
NAT14,POLA2,SKA3,PKP4,HNRNPAB,DEPDC1,ZCCHC8,C1orf112,URB2,HAUS4,TMED3,CLCC1,ORC1,FERMT3,KRR1,NUDT19,MLX,UCHL5,DNAAF2,GRSF1,RCSD1,LTN1,ANKRD13C,MYBL1,TACC3,TMX1,SMC4,ENPP4,TSPYL4,POLK,PBK,EMB,SLBP,ANLN,DDX39A,PICALM,RAD54B,STOML2,KIF18A,ZNF777,TMEM168,DDOST,STT3A,NEIL3,EIF2D,CEP55,SLC16A1,PSMC1,LRP8,SLC25A33,FAM72A |
| 3.136e-06 | -12.67 | GSE5455_EX_VIVO_VS_POST_24H_INCUBATION_MONOCYTES_FROM_TUMOR_BEARING_MOUSE_UP | MSigDB lists | GSE5455_EX_VIVO_VS_POST_24H_INCUBATION_MONOCYTES_FROM_TUMOR_BEARING_MOUSE_UP | 179 | 51 | 17377 | 2626 |
MIF,HIVEP3,GALK1,SNX27,SEC61G,UQCR10,TMEM41B,MAGED1,TRAK1,UCK2,PXMP2,HMGN3,SLC35B2,LYRM2,TFRC,NDUFS4,FKBP1A,RNF121,SNRNP25,PDXP,PSMD1,NDUFB4,TTC9C,NDUFS8,MRPL48,ERI3,SPTSSA,CLTB,MYBL1,UBE2M,SENP1,IMPA2,UBE2QL1,RBM15B,TIMM8B,SEPT8,PSMG1,CHCHD6,GLOD4,MID1IP1,MTHFD2,NSMCE2,NDUFA11,ITGB1,MEGF9,PPP1R11,PGAM1,MAPK1,MZT2B,FAF1,STARD3NL |
| 3.142e-06 | -12.67 | SNRNP40 (small nuclear ribonucleoprotein U5 subunit 40) | protein interactions | 9410 | 72 | 28 | 17029 | 2761 |
SART1,SNRNP200,RBM42,SUZ12,SF3B1,PPIE,CRNKL1,SREK1,USP39,PRPF3,WDR5,TXNL4A,APP,LMNA,RPA1,DDX23,RPA2,EIF4A3,DHX16,CHD3,EFTUD2,PML,PRPF4,YWHAZ,AQR,ECD,PRPF4B,CDC5L |
| 3.153e-06 | -12.67 | TFDP1 (transcription factor Dp-1) | protein interactions | 7027 | 43 | 20 | 17029 | 2761 |
MAX,GGA1,CDT1,PCGF6,E2F3,MIER2,COMMD4,COMMD6,COMMD8,LIN9,RB1,SERTAD2,CDC27,RBL1,SIAH1,E2F4,E2F1,CDK2,E2F2,RYBP |
| 3.155e-06 | -12.67 | GO_LARGE_RIBOSOMAL_SUBUNIT | MSigDB lists | GO_LARGE_RIBOSOMAL_SUBUNIT | 89 | 31 | 17377 | 2626 |
RPL29,RPL35,RPLP2,RPL8,MRPL12,MRPL43,RPL6,RPL38,RPL15,MRPL16,RPL27A,MRPL19,RPL11,RPL36,RPL23A,RPL37,MRPL2,MRPL55,RPL32,RPL17,MRPL27,RPLP1,RBM3,RPL19,MRPL11,MRPL21,MRPL13,RPL22L1,MRPL3,NSUN4,MRPL32 |
| 3.176e-06 | -12.66 | GO_NEGATIVE_REGULATION_OF_NITROGEN_COMPOUND_METABOLIC_PROCESS | MSigDB lists | GO_NEGATIVE_REGULATION_OF_NITROGEN_COMPOUND_METABOLIC_PROCESS | 1448 | 280 | 17377 | 2626 |
ZNF496,TXN,H2AFZ,KDM4A,TSC22D3,UBE2I,RBM4,CDK5,PA2G4,SRSF4,FNIP2,CRY2,SMARCE1,DNMT1,SRSF10,PLK3,ERCC1,KLF10,GABPA,AKT2,EHMT1,DDX20,AURKB,DOT1L,BRMS1,HHEX,SMAD2,RPS27A,RPS14,AXIN1,PRDX5,TFDP2,SMAD1,ARRB2,PDCD4,HDAC2,PRKAA1,EIF2AK4,PSEN1,METTL3,CDC73,CNOT3,TFAP4,SMC3,KLF16,HDAC7,PHF14,DAPK1,MSH2,GNAI2,LPCAT1,TNRC18,PABPC1,TERF2,ETV3,RBM42,FOXK1,MTA2,ZMYND11,GTPBP4,BCLAF1,ARID1A,CBFA2T2,FXR1,XRCC5,CAT,EPRS,PFDN5,ETS2,RBMX,CEBPG,PIAS2,CNOT6,YY1,ZNF830,RNF139,CDKN2A,EGLN1,ZNF296,DNMT3A,UBR2,SUZ12,MAGED1,WDTC1,RCOR3,PAIP2,TERF2IP,SP100,MTA1,CDKN1B,ATF2,RBM15,CGGBP1,RNF169,SAP30,EID1,ERF,DRAP1,CIRBP,RNPS1,CUL3,H2AFV,TRIM28,CHCHD3,ZNF282,DGCR8,HIPK2,STAT1,H2AFX,TRIM32,BEND3,LRP8,POLQ,NCOR2,DEPDC1,MECP2,SRSF6,TCF3,SECISBP2,BLM,FOXO3,HMG20A,MAD2L2,WWP2,SUV39H2,CREB1,CITED2,CNOT6L,NCOA2,MSH6,TNFAIP3,ILF3,ZP3,CBX3,KEAP1,ZHX1,GPS2,PITX1,LRPPRC,PML,HMGB2,DDX5,PARP10,IGBP1,PURA,CPEB2,RORB,THOC1,TRIM11,SIRT2,PRNP,CREM,EIF4A3,GLIS2,JAZF1,METTL14,SIVA1,ZNF639,ETV6,NOC2L,OGG1,ARID4A,TRIM14,CCAR1,RYBP,PTPRK,SP3,PLK1,DEAF1,TRIM8,NCK1,BAZ2A,PBXIP1,VHL,EZR,CDC6,BRCA1,PRKRA,PAF1,EIF4ENIF1,TONSL,ZNF268,CHEK2,CLU,BEND6,RPS26,POT1,ZNF564,UBE2D3,PHB2,CENPF,NACA,TIA1,CTCF,MEF2A,SRRT,TTF1,RB1,NFATC3,MLX,MBD2,ZNF746,CTR9,TIMELESS,MDFIC,ZNF189,CREG1,CIC,LDB1,EIF2AK1,RTF1,DAPK3,ZNF174,TSC1,ORMDL2,SYNCRIP,NFIL3,NLRC5,SIAH2,ZFP90,TOB1,N4BP2L2,MBD1,USP7,CYLD,MPHOSPH8,FOXM1,SMARCA4,IRF3,DUSP22,MXD1,HNRNPA2B1,SAP130,MDM2,TARDBP,STRAP,RLIM,MOSPD1,PPIF,BTG2,PCGF6,ATXN1,NFATC2,MBD3,RBL1,HNRNPR,STAT6,ARNTL,DNAJC17,H3F3A,SMAD4,CBX4,UNK,DNAJC2,TRIP12,DAP,ARID5A,NKRF,PAWR,MXD4,FZD6,BRD7,H2AFY,STAT3,RBM15B,TGFB1,ZNF202,BTAF1,HELB,PSPC1,RCOR1,PRMT2,MEN1,UPF1,BIRC5,E2F1,RBPJ,NR2F2,TERF1,IFI16 |
| 3.183e-06 | -12.66 | POMEROY_MEDULLOBLASTOMA_PROGNOSIS_DN | MSigDB lists | POMEROY_MEDULLOBLASTOMA_PROGNOSIS_DN | 42 | 19 | 17377 | 2626 |
UBE2D3,RPL29,IFRD1,CENPF,MYBL2,RPS10,TKT,B4GALT1,SLC29A1,RPL27A,RPL11,FGFR3,IARS,ATIC,COX8A,SRI,CDC25B,BYSL,LDHB |
| 3.183e-06 | -12.66 | GO_NADH_DEHYDROGENASE_COMPLEX | MSigDB lists | GO_NADH_DEHYDROGENASE_COMPLEX | 42 | 19 | 17377 | 2626 |
NDUFA5,NDUFV2,NDUFS1,NDUFB6,NDUFA4,NDUFA7,NDUFB1,FOXRED1,PARK7,NDUFS7,NDUFS4,NDUFV1,NDUFA2,NDUFB4,NDUFA11,NDUFB9,NDUFS8,NDUFS5,NDUFA3 |
| 3.183e-06 | -12.66 | BURTON_ADIPOGENESIS_PEAK_AT_24HR | MSigDB lists | BURTON_ADIPOGENESIS_PEAK_AT_24HR | 42 | 19 | 17377 | 2626 |
GALK1,TK1,PTTG1,RRM1,RACGAP1,RANGAP1,NUSAP1,AURKB,CCNB1,ANLN,STMN1,SRSF1,CCNA2,PRC1,H2AFX,KIF22,KPNA2,SNRNP70,UBE2C |
| 3.252e-06 | -12.64 | PHLDA3 (pleckstrin homology like domain family A member 3) | protein interactions | 23612 | 24 | 14 | 17029 | 2761 |
PDCD6IP,SMAP1,AHSA1,EFTUD2,LRPPRC,DNAAF5,TNPO3,SLC25A12,CDK2,PDXDC1,APP,NUP205,IPO4,HNRNPM |
| 3.263e-06 | -12.63 | GCGNNANTTCC_UNKNOWN | MSigDB lists | GCGNNANTTCC_UNKNOWN | 115 | 37 | 17377 | 2626 |
OTUD5,ZCCHC9,TMEM203,CHERP,SF3B1,DCTN2,MOGS,AKT1S1,SND1,ZNF79,FBXO22,ZER1,HNRNPA2B1,FIZ1,VPS13B,SP3,ZNF524,NRAS,DDX24,AKT2,AMD1,ADSL,PNPLA8,DNAJA1,EIF4H,APPL1,CBX3,C1orf122,WAS,TBC1D17,FBXO28,E2F4,TBPL1,RWDD4,GALNT10,ZBTB11,NAA60 |
| 3.272e-06 | -12.63 | GO_ENERGY_DERIVATION_BY_OXIDATION_OF_ORGANIC_COMPOUNDS | MSigDB lists | GO_ENERGY_DERIVATION_BY_OXIDATION_OF_ORGANIC_COMPOUNDS | 208 | 57 | 17377 | 2626 |
COX5B,NDUFA5,COX15,NDUFV2,NDUFS1,NDUFB6,UGP2,PPP1R2,SUCLG1,NDUFAF2,UQCR10,MDH2,MECP2,SLC25A12,NDUFA4,COX4I1,CYCS,GYG1,SDHA,NDUFS7,EPM2A,NDUFS4,CALM2,FASTKD3,PPP1R3B,NDUFV1,NDUFA2,NDUFB4,IL6ST,CS,SUCLG2,NDUFB9,NDUFS8,CYC1,NDUFA3,PHKG2,AKT2,IDH3A,TBRG4,NDUFA7,OGDH,NDUFB1,TAZ,POLG2,CAT,SDHB,GNAS,RPS27A,NDUFA11,COX7A2L,COX8A,COX5A,DHTKD1,UQCRH,MDH1,NDUFS5,IDH3B |
| 3.279e-06 | -12.63 | GSE17721_0.5H_VS_24H_GARDIQUIMOD_BMDC_DN | MSigDB lists | GSE17721_0.5H_VS_24H_GARDIQUIMOD_BMDC_DN | 184 | 52 | 17377 | 2626 |
POLA2,ANXA6,SHPRH,C16orf87,TMEM97,TM9SF3,PXMP2,CDC42SE2,LACTB2,CCNL2,TMEM165,CHD1,CDC73,RGS1,WDR48,TMCC3,CDK5,VAV1,MRPL50,ATP6V0B,NAPG,RAB8A,NRF1,ATP2A2,SNX18,CWC27,ZNF260,CAPZA1,LTN1,RNF135,SLC35A1,LARS,NXT1,FAM49B,NOA1,PSMB7,PCGF6,RABIF,ARHGEF12,NDRG3,CAND1,PPP2CA,RAB18,JAK1,SERF2,RAB24,HNRNPH3,GADD45B,SOCS4,PIAS2,YY1,RRS1 |
| 3.279e-06 | -12.63 | GSE7460_CD8_TCELL_VS_CD4_TCELL_ACT_DN | MSigDB lists | GSE7460_CD8_TCELL_VS_CD4_TCELL_ACT_DN | 184 | 52 | 17377 | 2626 |
ANKRD27,UBE2E2,PKP4,GOLPH3L,MDH2,ADPGK,SNN,APP,BCAT2,TMCC3,PRNP,FKBP1A,RB1,AHCTF1,LRRC8D,METTL14,PPP4R1,ANP32A,ANXA5,MDFIC,CENPM,PLCL2,SPTSSA,ZRANB1,CLN6,IFT46,NSUN4,GM2A,CGGBP1,GCC2,FOXK1,CREG1,AKT2,SLC25A22,SUMF2,NUSAP1,UBE4B,SEPT7,RAB1A,ZFAND5,FADD,RPA1,PPP2CA,MTMR3,DAP3,TMEM168,ETS2,MYO18A,SH3GLB2,MBOAT1,CD81,AP2S1 |
| 3.279e-06 | -12.63 | GSE5463_CTRL_VS_DEXAMETHASONE_TREATED_THYMOCYTE_DN | MSigDB lists | GSE5463_CTRL_VS_DEXAMETHASONE_TREATED_THYMOCYTE_DN | 184 | 52 | 17377 | 2626 |
CYTIP,GOLPH3L,UBN1,CDT1,ENSA,POMP,MAN1A1,SLC25A36,APLP2,DNAJC8,SMC3,PSMA6,PPIG,FUT8,AXIN2,BCL2,RNASEH2A,SPTSSA,ILKAP,ABCC5,CSTF1,USP34,RPAP3,RFC3,TNFAIP3,MIOS,PRIM2,GABPA,ELL2,RAD51AP1,MKI67,CRNKL1,ADSL,BCLAF1,WDR81,NDRG3,CYB5A,NSA2,PON2,FNTA,DDOST,TMED10,DCK,RPS14,NFIL3,PGRMC1,FKBP5,TCOF1,CD81,NMD3,TERF1,HIGD2A |
| 3.279e-06 | -12.63 | GSE42021_CD24LO_TREG_VS_CD24LO_TCONV_THYMUS_DN | MSigDB lists | GSE42021_CD24LO_TREG_VS_CD24LO_TCONV_THYMUS_DN | 184 | 52 | 17377 | 2626 |
PPIB,PRKCSH,DAP,DYNLL1,STRN4,MAN2B1,MXD4,PSEN1,REEP5,BCAT2,GTF2F1,WWP2,TMEM179B,CDK5,RAB8A,TBC1D22A,MEA1,MRPL34,MSH2,RPL19,SLC38A10,RNASEH2A,TALDO1,NUP85,LYPLA2,SAP30,CDC37,BAK1,CSNK1G2,TIMM8B,EIF3L,PTPN18,SEC61B,GUK1,RBM42,PPP1R21,NSUN2,ARPC1A,MBD3,MAPK3,STOML2,YIF1A,EIF3K,SDHB,GNAS,SEC61A1,CSK,PSMD3,CTSA,SCARB1,PREPL,ATP6V0E1 |
| 3.282e-06 | -12.63 | response to endoplasmic reticulum stress | biological process | GO:0034976 | 246 | 65 | 17256 | 2622 |
ATXN3,ADD1,FAM129A,CXXC1,PPP1R15B,TMX4,UBQLN2,RNF103,SSR1,ATP2A2,SHC1,UBA5,PIK3R2,TARDBP,PDIA6,CTDSP2,DCTN1,BAK1,SEC61B,NCK1,EDEM2,SERP1,ANKZF1,DNAJC10,SEC61A1,SEL1L,ATF6,PSMC1,USP13,TMEM33,TMUB1,SEC61G,UFC1,TMX3,FLOT1,UBE4A,SDF2L1,EIF2AK4,LMNA,NPLOC4,DNAJB9,RHBDD1,DDRGK1,RNF121,BCL2,MYDGF,ATP6V0D1,RNF5,TMX1,PREB,ERLIN1,MAN1B1,ERO1A,SYVN1,UBE4B,PSMC4,SEC31A,YIF1A,DERL1,TATDN2,PML,ASNA1,MAP3K5,ECPAS,RNF139 |
| 3.305e-06 | -12.62 | BANF1 (barrier to autointegration factor 1) | protein interactions | 8815 | 76 | 29 | 17029 | 2761 |
DNAJC2,COX15,RECQL,MTA2,EYA1,TUFM,ERBIN,CNTROB,SNRPD3,PKM,SOX4,VDAC1,ATP5PF,SDHA,LMNA,HSPA1B,EVC2,CBX3,ZNF428,SUB1,LUC7L3,BANF1,BCL7C,TRA2B,FBL,RBBP4,SMARCE1,DDB1,HDAC2 |
| 3.334e-06 | -12.61 | Ccdc12 (coiled-coil domain containing 12) | protein interactions | 72654 | 27 | 15 | 17029 | 2761 |
SNRNP200,CDC40,NUP188,XAB2,PPIL2,VAV2,PPIE,BUD31,CRNKL1,DHX8,AQR,PPWD1,MRPL3,PRPF19,CDC5L |
| 3.334e-06 | -12.61 | TIMM9 (translocase of inner mitochondrial membrane 9) | protein interactions | 26520 | 27 | 15 | 17029 | 2761 |
TIMM8B,SART1,NDUFV1,TIMM13,TIMM29,DHX9,NADK2,COX5A,CTSA,NIT2,PTGES3,ATF2,HNRNPM,HTRA2,NUDC |
| 3.347e-06 | -12.61 | HSP90AA1 (heat shock protein 90 alpha family class A member 1) | protein interactions | 3320 | 806 | 179 | 17029 | 2761 |
NPHP4,MAX,ST13,CXXC1,YTHDC2,CUL1,CSNK2A1,NANS,BECN1,EDRF1,MIS12,RPL23A,PRNP,CDK5,PSMD1,THAP4,TTC9C,FBXW2,FNIP2,CRY2,TTC4,MAST2,ASB6,CDC37,CDC5L,SNRNP200,RHOBTB3,AKT2,VHL,MCL1,AURKB,BRCA1,MCM2,SLC25A5,BRMS1,FBXO28,PDRG1,LIMK1,IARS2,STK11,COPS6,FBXL3,WSB2,HSPH1,CHTF18,PRKAA1,CDK13,PMF1,CDC73,CFLAR,C12orf10,RB1,MCM5,PPIL2,EFTUD2,DAPK1,BCL2,GNAI2,LRSAM1,TERF2,PREB,HP1BP3,GBA,EIF2AK1,TOMM40,PKM,METTL22,ISG15,DAPK3,PI4K2A,CAND1,MAGED2,EPRS,KLHL15,MDH1,CNOT6,ATP5F1A,MAP3K5,PPP6R3,CDK2,CDKN2A,RNF114,EGLN1,TRIM41,ATXN3,CYLD,TP53RK,FOXM1,RAF1,RPS6KA1,MYH9,IRF3,PRKACA,LYN,PCBP1,APP,MDM2,SHC1,SOCS6,CDKN1B,TARDBP,LMAN1,ATF2,SPSB3,PRPF19,CCT2,RPL29,MAP4K4,CUL3,CRNKL1,PCGF6,DNAJA1,RPSA,EIF3H,DAP3,HSPA4,JAK1,DSN1,DDOST,CLK3,TAB2,GUCY1B1,FASTK,STK38,ARNTL,CAMKMT,H2AFX,FKBP5,TRIM32,FUS,PPP5C,MAPK1,TUBB,PRPF4B,MIF,UNK,AGO2,ATP5F1B,IP6K2,CDK11B,BLM,CSNK1A1,FBXO3,RFWD3,FGFR3,GRK2,PTEN,HUWE1,RPL17,AHSA1,PTGES3,MAP3K14,STAT3,CAMK2G,NUDC,SPTAN1,RPAP3,PDPK1,TNFAIP3,PRKDC,LDHA,ILF3,TUFM,FBXO9,ANAPC2,PCGF1,CDK11A,HSPA1B,GNA12,KEAP1,RPL32,BIRC5,ZC3H7B,BBX,KBTBD7,DTX4,WDR76,RPS6KC1,TERF1 |
| 3.348e-06 | -12.61 | VTN (vitronectin) | protein interactions | 7448 | 129 | 42 | 17029 | 2761 |
SF3B1,DHX9,CSNK2A1,USP39,GLUD1,PRKACA,ITGB5,APP,KTN1,ZNF696,FASTKD3,ITGB8,BUD31,HNRNPM,SRSF10,HP1BP3,CDC5L,PRPF19,SRSF11,TGFB1,GOPC,MRS2,WDR18,SF3B6,SMU1,ILF3,LNX2,SEPT7,DHX15,SRSF1,LEMD2,NAP1L1,ZNF777,NEK1,RBM25,TTLL4,HNRNPR,LUC7L3,SAFB,DDX5,RNF14,DDB1 |
| 3.348e-06 | -12.61 | RPL13A (ribosomal protein L13a) | protein interactions | 23521 | 129 | 42 | 17029 | 2761 |
NIFK,RPS2,CYLD,RPLP2,RPL15,CUL1,ETS1,PABPC4,RPL11,RPL23A,RPA2,GOLM1,EIF4A3,PTEN,HUWE1,RPL17,RBM34,ZNF746,RPL19,TARDBP,FBL,ZC3H3,PABPC1,RPL35,CUL3,RPL8,RPL38,RPL6,RPS10,MCM2,RPL27A,RPS9,RPSA,RPA1,CAND1,RPL36,FNTA,SEC61A1,RPL32,RPS14,RRS1,RPS26 |
| 3.353e-06 | -12.61 | RPL3 (ribosomal protein L3) | protein interactions | 6122 | 177 | 53 | 17029 | 2761 |
RPS15,RPS2,CYLD,RPLP2,SF3B1,MECP2,SUMO2,RAC1,RPL15,CUL1,EBNA1BP2,NENF,RPL11,RPL23A,LYAR,EIF4A3,RPL17,HUWE1,RBM34,ZNF746,RPL19,TARDBP,PABPC1,PPAN,STAU1,RPL35,RPS10,RPL6,RNPS1,CUL3,RPL8,ILF3,RPL38,TUFM,RPS24,BRCA1,MCM2,RPL27A,MAK16,RPS9,RPSA,CAND1,RPL36,SEC61A1,RPL32,RPS14,RPLP1,RRS1,CDK2,ARRB2,RPS26,NUMB,SMNDC1 |
| 3.353e-06 | -12.61 | GRK5 (G protein-coupled receptor kinase 5) | protein interactions | 2869 | 177 | 53 | 17029 | 2761 |
CTDP1,AP3M2,DHX9,OLA1,MYH9,MYO9B,ARF1,KCMF1,PIP4K2A,LYAR,PSMD2,EIF4A3,PPIG,EFTUD2,MRPS27,HADHB,GEMIN4,FTSJ3,CFL1,SPTAN1,CDC37,RBX1,AKT2,PRKDC,MAP4K4,ILF3,TUFM,WDR82,BMS1,BCLAF1,ADRB2,ABCF1,DHX15,EIF3A,MAT2A,ARF4,GINS4,SRSF1,XRCC5,UBTF,HSPA4,STK38,MAP4,U2SURP,LRPPRC,GLG1,RBMS1,YWHAZ,TCOF1,PPP6R3,PSMC1,DCAF5,DDB1 |
| 3.357e-06 | -12.60 | BASSO_B_LYMPHOCYTE_NETWORK | MSigDB lists | BASSO_B_LYMPHOCYTE_NETWORK | 133 | 41 | 17377 | 2626 |
CYLD,HNRNPAB,ANXA6,HLA-E,SRGN,DBF4,UCK2,TPX2,TGOLN2,CYCS,EBNA1BP2,CCNB1,HDDC2,PSMD2,PCNA,PSMD1,CCNA2,SP100,SAR1A,AHSA1,BUD31,MDFIC,CYC1,MVP,ZMYND11,WDR18,PSMB7,MRPL12,ITM2A,TOMM40,SRSF1,HHEX,AHNAK,PRDX3,TIMM17A,RUVBL2,RPS26,MRPL3,BYSL,N4BP2L2,SSRP1 |
| 3.367e-06 | -12.60 | REN_ALVEOLAR_RHABDOMYOSARCOMA_DN | MSigDB lists | REN_ALVEOLAR_RHABDOMYOSARCOMA_DN | 396 | 94 | 17377 | 2626 |
TMEM184B,NQO1,ADAM10,CAST,RAC1,HEXB,UCK2,MYH9,RRAGC,NANS,CMTM6,BCAP31,RAB21,APLP2,ATG3,GRSF1,LMAN1,CLTB,LRRC59,SEC61B,TIMP2,COQ10B,MTMR6,MCFD2,RAB1A,CHMP2B,SERP1,ARF4,NECAP2,ABHD5,DPYSL3,TRAM2,JAK1,STAT6,FTSJ1,AP1S1,ADAM9,CLU,PDXK,CHPF2,AP2S1,ATP6V0E1,RHOC,RAB23,B4GALT1,TMED3,ARF1,TMEM165,ITGB5,PSMD9,REEP5,COPB2,MCTS1,EBP,GNS,CLIC4,PTEN,ARPC5,RRBP1,TPST1,ANXA5,TAGLN2,CNN2,GNAI2,ATP6V0D1,S100A6,SLC25A1,PDLIM2,TGFB1,VOPP1,ELOVL5,RHOA,SNX2,ELL2,NQO2,WDR1,HEBP2,GORASP2,LY6E,VKORC1,KLF6,NEU1,CAT,NUCB1,PDCD6,UAP1,TFE3,SNAP23,PRPS2,PGRMC1,PITPNA,PKD2,PDLIM5,CD81 |
| 3.376e-06 | -12.60 | LIMA1 (LIM domain and actin binding 1) | protein interactions | 51474 | 255 | 70 | 17029 | 2761 |
TOMM20,LUZP1,NF1,SUZ12,RAC1,MYH9,TWF2,SEC16A,LYN,APP,PARK7,EDC3,DST,ZBTB21,UBXN2A,RAP1A,CCDC50,CDC42,AP2B1,CDC25B,CLTB,CFL1,PPP1R18,BIRC3,GOPC,RAB1A,ANLN,USP21,RPSA,GIGYF1,EIF3H,AFDN,AHNAK,CORO1C,MYO18A,BCL7C,ACTB,ARRB2,MAPRE1,FAM53C,FLOT1,RTKN,RPA2,GSTK1,PTEN,KIF13B,HDAC7,CAPZA1,GTSE1,MYO5A,EEF1D,CSNK1G3,SPTAN1,PPP1R9B,CYFIP1,RHOA,DENND4C,WDR1,KRAS,PLEC,CAPZA2,RAB3IP,PICALM,DAPK3,RPA1,SH3BP5,INF2,PDLIM1,FAM110A,CDK2 |
| 3.396e-06 | -12.59 | GSE22611_NOD2_TRANSDUCED_VS_CTRL_HEK293T_STIMULATED_WITH_MDP_2H_UP | MSigDB lists | GSE22611_NOD2_TRANSDUCED_VS_CTRL_HEK293T_STIMULATED_WITH_MDP_2H_UP | 170 | 49 | 17377 | 2626 |
DDX58,CORO7,TMEM184B,GMFG,RAB11B,ADAM10,EYA1,DAP,DLGAP4,CERK,AGPAT3,SIRT2,ATP6V1B2,MAP1LC3B,PPP1R16B,LYN,COMMD8,STAM,FAM8A1,MXD1,GNS,ATP6V0B,CRAT,AP1M1,MDFIC,CNOT6L,FAM3A,BIRC3,PIP4K2C,SOX4,TOLLIP,COMMD4,RAB5B,SERP1,PLEKHF2,NEU1,TMEM127,PEX5,SNAP29,ARNTL,PTPN7,ATP6V0C,NCOA1,RNF14,GLCCI1,ABCA1,HIPK3,NRBP1,ANXA11 |
| 3.397e-06 | -12.59 | GPATCH4 (G-patch domain containing 4) | protein interactions | 54865 | 104 | 36 | 17029 | 2761 |
ZCCHC9,NOP2,RPL15,CUL1,TOP2B,EBNA1BP2,BRIX1,TTF1,MYEF2,ZNF92,DDX56,NVL,RBM34,RPF2,DDX31,FBL,FTSJ3,NOL12,STAU1,DDX24,ZNF512,GTPBP4,CUL3,BUD13,GAR1,MAK16,RPL36,NSA2,RPL32,NEIL3,BBX,RRS1,OAZ1,ZC3HAV1,DDX52,CCDC137 |
| 3.397e-06 | -12.59 | MTREX (Mtr4 exosome RNA helicase) | protein interactions | 23517 | 104 | 36 | 17029 | 2761 |
UNK,MZT1,NOP2,ZCCHC8,TRMT6,CUL1,KIF2C,EFL1,PABPC4,RPA2,EXOSC7,EIF4A3,CWC27,ZNF746,EXOSC1,CTPS1,YBX1,TARDBP,UPF2,PABPC1,TERF2,CDC5L,EXOSC6,GBA,RNPS1,CUL3,EXOSC9,DHX15,EIF3H,CAND1,RPA1,DDX5,RRS1,PPP2R2D,IFI16,CAPN1 |
| 3.404e-06 | -12.59 | GO_POSITIVE_REGULATION_OF_MITOTIC_METAPHASE_ANAPHASE_TRANSITION | MSigDB lists | GO_POSITIVE_REGULATION_OF_MITOTIC_METAPHASE_ANAPHASE_TRANSITION | 14 | 10 | 17377 | 2626 |
PLK1,RB1,GOLGA2,PTEN,GORASP1,NSMCE2,CUL3,RAB1A,ESPL1,FBXO5 |
| 3.404e-06 | -12.59 | GO_POSITIVE_REGULATION_OF_MITOTIC_SISTER_CHROMATID_SEPARATION | MSigDB lists | GO_POSITIVE_REGULATION_OF_MITOTIC_SISTER_CHROMATID_SEPARATION | 14 | 10 | 17377 | 2626 |
PLK1,RB1,GOLGA2,PTEN,GORASP1,NSMCE2,CUL3,RAB1A,ESPL1,FBXO5 |
| 3.404e-06 | -12.59 | GO_POSITIVE_REGULATION_OF_METAPHASE_ANAPHASE_TRANSITION_OF_CELL_CYCLE | MSigDB lists | GO_POSITIVE_REGULATION_OF_METAPHASE_ANAPHASE_TRANSITION_OF_CELL_CYCLE | 14 | 10 | 17377 | 2626 |
PLK1,RB1,GOLGA2,PTEN,GORASP1,NSMCE2,CUL3,RAB1A,ESPL1,FBXO5 |
| 3.412e-06 | -12.59 | GSE26559_TCF1_KO_VS_WT_LIN_NEG_CELL_UP | MSigDB lists | GSE26559_TCF1_KO_VS_WT_LIN_NEG_CELL_UP | 189 | 53 | 17377 | 2626 |
CYLD,FEZ2,KIAA0100,CAST,SRGN,PRKAA1,EIF1B,SAFB2,REEP5,ABHD14A,FZD6,CLIC4,DAPK1,ATP6V0A2,FEM1B,TP53BP2,MAP3K14,MAML1,MED22,SMC4,ATP6V1G1,SRPK2,FDFT1,PLK3,ERCC1,MLEC,RBM42,ACSL3,MTMR6,HTATIP2,BICD2,TOMM40,ICAM2,MACF1,STK17B,YIF1A,KIF2A,FBXO21,HSPA4,SERTAD2,SEC23IP,PLAA,PPP2R5A,TBL3,GOLGA8A,MAP4,NFIL3,NAGLU,BAZ1B,MEGF9,ACADM,PIEZO1,MAPK1 |
| 3.412e-06 | -12.59 | GSE26030_TH1_VS_TH17_RESTIMULATED_DAY5_POST_POLARIZATION_UP | MSigDB lists | GSE26030_TH1_VS_TH17_RESTIMULATED_DAY5_POST_POLARIZATION_UP | 189 | 53 | 17377 | 2626 |
CLSPN,ANXA6,SEC61G,UFC1,TRIO,POMP,UBE2I,VPS25,NDUFS4,TMEM179B,SUB1,CTSS,NDUFA2,NDUFB4,RPL17,SIVA1,BTF3L4,MRPL34,NDUFB9,S100A6,IMPA2,TMEM160,SAP30,TIMM8B,PTPN18,POLR2I,RPL35,EMB,MRPL43,RFXANK,PSMB7,RPL38,EMP3,GLO1,NDUFA7,EIF2A,RIT1,TOMM40,RBM38,ALKBH6,NECAP2,EIF3K,PFDN5,LSM6,LIMK1,NDUFA11,MRPL27,ITGB1,COX8A,BTF3,FAU,WDR91,CD81 |
| 3.442e-06 | -12.58 | C1qbp (complement component 1, q subcomponent binding protein) | protein interactions | 12261 | 61 | 25 | 17029 | 2761 |
COX5B,CMAS,GOLIM4,NDUFS1,PHB2,DHX29,ERLIN1,ZFP91,VDAC2,FLOT1,ATP6V0A1,CHCHD2,NDUFA7,ATP6V1B2,CHMP2B,LUC7L,STOML2,CHCHD3,NDUFA2,YBX1,CHMP4B,ATP5F1A,MBD6,ALDH18A1,SLC12A2 |
| 3.465e-06 | -12.57 | GO_POSITIVE_REGULATION_OF_CELL_CYCLE_ARREST | MSigDB lists | GO_POSITIVE_REGULATION_OF_CELL_CYCLE_ARREST | 81 | 29 | 17377 | 2626 |
PLK3,TGFB1,BTG2,BRCA1,SOX4,CCNB1,PRKACA,CRLF3,RBM38,CNOT3,MDM2,PCNA,RPS27A,CENPJ,E2F4,TFDP1,PML,UHRF2,E2F1,GTSE1,CDKN1B,PKD2,CNOT6,CHEK2,TFDP2,CNOT6L,CDK2,CARM1,CDKN2A |
| 3.470e-06 | -12.57 | RPL23 (ribosomal protein L23) | protein interactions | 9349 | 218 | 62 | 17029 | 2761 |
BCCIP,RPS15,NIFK,RPS2,CYLD,NOP2,RPLP2,RPL15,CUL1,BRIX1,APP,NDUFS4,RPL11,RPL23A,MDM2,ITGB8,CDC42,PTEN,RPL17,HUWE1,ATG3,AHSA1,ZNF746,RPL19,TARDBP,FBL,HNRNPM,RPL35,MRPL12,RPS10,RPL6,TUFM,RNPS1,CUL3,ILF3,RPL8,RPL38,RPS24,TOR1AIP2,NFATC2,BRCA1,MCM2,RPL27A,SLC25A5,MRPS14,RPS9,RPSA,CAND1,RPL36,RPL32,RPS27A,RPS14,RPLP1,CBWD1,CLU,COPS6,RRS1,CDK2,SMURF1,RPS26,TUBB,SSSCA1 |
| 3.504e-06 | -12.56 | MRPL1 (mitochondrial ribosomal protein L1) | protein interactions | 65008 | 84 | 31 | 17029 | 2761 |
MRPL9,CYLD,MRPL42,MRPL39,GOPC,PTTG1,MRPL12,MRPL43,TUFM,CIRBP,ILF3,CUL3,MRPL16,SDHA,MRPL19,APP,CAND1,MRPL50,MRPL2,COQ4,CORO1C,MRPL34,RBM3,MRPL40,MRPL11,MRPL21,MRPL13,MRPL3,ZC3H3,MRPL32,MRPL57 |
| 3.507e-06 | -12.56 | GO_NEGATIVE_REGULATION_OF_PROTEIN_METABOLIC_PROCESS | MSigDB lists | GO_NEGATIVE_REGULATION_OF_PROTEIN_METABOLIC_PROCESS | 1041 | 210 | 17377 | 2626 |
ZBED3,FGFR1OP,ST13,TSC2,NF1,UBN1,KDM4A,PPP1R15B,FAM129A,XIAP,CSNK2A1,SIRT2,CCNB1,PPP1R16B,BIRC2,PARK7,RBM4,PRNP,CDK5,CALM2,CDKN2C,PSMD1,EIF4A3,METTL14,NOC2L,CRY2,DNMT1,SENP1,PLK1,BAK1,AATF,NCK1,PBK,AKT2,GMFB,EZR,LRP5,BRCA1,SOX4,PRKRA,HHEX,EIF4ENIF1,SMAD2,RPS27A,PSMD8,LIMK1,PRDX5,SOCS4,OGT,ROCK1,CLU,DVL1,CLN3,SMAD1,ARRB2,PSMC1,HDAC2,PDCD4,SVIP,HSPH1,ZCCHC9,GMFG,DNAJB2,UBXN1,CENPF,CIB1,TIA1,EIF2AK4,RGS2,PSMD9,PSEN1,SRRT,METTL3,CNOT3,FKBP1A,TFAP4,CD59,RB1,FBXO7,ARL6IP1,DAPK1,MVP,SOCS5,ZMYND11,GBA,GTPBP4,PSMA1,ITM2A,EIF2AK1,FXR1,KDM3A,ISG15,PSMB3,DAPK3,PSMC4,MASTL,AKAP1,TSC1,EPRS,MBIP,CDC27,SYNCRIP,CSK,DUSP3,SIAH2,NUP62,CNOT6,GPI,SNRNP70,CDK2,RNF139,TOB1,CDKN2A,ZNF207,PPP1R37,ASH1L,FOXM1,CAST,RPS6KA1,RAF1,PTTG1,DUSP22,LYN,APP,PAIP2,HNRNPA2B1,APLP2,MDM2,PSMA6,TNFAIP8,UCHL5,PIN1,SOCS6,CDKN1B,TARDBP,ANAPC7,GPD1L,STRAP,CTDSP2,PDCL3,SNX25,TIMP2,BIRC3,BTG2,PSMB7,CUL3,CIRBP,PKMYT1,DNAJA1,CDC23,PSMB9,SOCS7,PPP2CA,DNAJC10,IDE,CDC16,DGCR8,HNRNPR,PSMD3,CORO1C,STK38,GADD45B,PPP5C,SMAD4,PARD3,MIF,BCL2L12,UNK,TRIP12,MECP2,AKT1S1,MAD2L2,FBXO5,PTPN2,PSMD2,PTEN,H2AFY,CNOT6L,STAT3,TGFB1,PDPK1,TNFAIP3,PRKDC,PRKAR1B,ILF3,RFFL,ANAPC2,WDR81,MEN1,PICALM,HSPA1B,SH3BP5,LEMD2,UPF1,PRDX3,BIRC5,GPS2,GLG1,PML,PPP1R11,NR2F2,UBE2C,PARP10,IGBP1,CPEB2,HIPK3,PURA,TERF1,IFI16,ANAPC4 |
| 3.522e-06 | -12.56 | oxidoreductase complex | cellular component | GO:1990204 | 104 | 34 | 18223 | 2701 |
NDUFA5,NDUFV2,NDUFS1,NDUFB6,UQCR10,RRM1,NDUFA4,SDHA,PARK7,NDUFS7,NDUFS4,PDK2,NDUFV1,NDUFA2,NDUFB4,NDUFB9,NDUFS8,CYC1,GPD1L,NDUFA3,KAT2A,DMAC2,RRM2,NDUFA7,OGDH,NDUFB1,FOXRED1,PDHX,SDHB,NDUFA11,DHTKD1,UQCRH,NDUFS5,GCSH |
| 3.523e-06 | -12.56 | catalytic activity, acting on a protein | molecular function | GO:0140096 | 2313 | 430 | 17224 | 2647 |
FGFR1OP,KDM4A,ADAM10,MAP3K7CL,CXXC1,ZDHHC8,XIAP,CUL1,USP39,NHLRC3,CCNB1,UBE2I,PARK7,FBXO22,EEF2K,CDK5,PSMD1,NEK6,FBXW2,MAST2,CDC25B,MARCH2,RNF26,MGAT5,RHBDD2,SENP1,USP34,PLK3,AKT2,PBK,EHMT1,LACTB,TOPORS,MIER2,AURKB,GALNT7,USP22,ICMT,CCNF,DOT1L,MAP3K4,BRMS1,MKNK1,RAD18,LIMK1,TPP2,PTPN7,OGT,ATE1,PTPDC1,RNASEL,KLHL42,FBXL3,ZNF598,LONP2,HDAC2,ZNF720,PPIB,PRKAA1,TRIO,CYCS,ZNRF3,EZH1,EIF2AK4,PSEN1,APH1B,WDR48,CFLAR,ATG4A,FKBP1A,RNF121,PDXP,KLHL5,ZNRF2,HDAC7,FBXO7,PPP4R1,DAPK1,TPST1,FBXL7,RNF135,PHKG2,UBE2QL1,PIGT,CPQ,MAPKAPK3,COQ8A,MTA2,ERO1A,USP10,ARMT1,KDM3A,MAP2K2,PSMB3,PTPRF,FNTA,CSK,DUSP3,CSNK1G1,SETD3,USP32,PPP3R1,PTAR1,PIAS2,VCPIP1,MAP3K5,CDK2,RNF14,RNF139,NRBP1,EGLN1,TP53RK,ATXN3,UBR2,SUZ12,RPS6KA1,RAF1,RAC1,KLHL18,PRKACA,ANKIB1,CPNE3,PRKD3,FBXL6,CCNA2,KDM2A,SIAH1,MTMR4,UCHL5,MTA1,CDKN1B,TTC3,RNF19A,ILKAP,CDK12,SAP30,CPNE1,ULK3,ERMP1,MAP4K4,TAOK1,CUL3,KIAA1586,PKMYT1,CDC23,PSMB9,TRIM28,FKBP3,ANKZF1,AMZ2,PPP2CA,PPP2R5A,JAK1,NSMCE2,HIPK2,CAMKMT,PPA2,RNF38,TRIM32,PPP5C,PITRM1,EYA2,CSNK1D,USP13,ADAM23,PRPF4B,OTUD5,ZFP91,BRAP,CBLL1,JMJD6,UBE4A,WDR5,POFUT1,WWP2,FBXO3,RFWD3,PPP1R3B,CCNK,CAPN2,PSMD2,SUV39H2,PTEN,HUWE1,FUT8,PTPN11,FEM1B,LTN1,UBE3B,MAP3K14,GTF2H2,FBXL19,UBE2M,LYPLA2,TMX1,PDPK1,PPP3CA,TNFAIP3,LONRF3,KAT2A,NEK7,USP42,TBRG4,FBXO9,ANAPC2,OTUD3,SPPL2B,MARK2,ZNF862,FBXO21,KEAP1,LTBP4,TTLL4,CAPN7,MAPK6,PPP1R11,DUSP11,ESPL1,ANAPC4,CCNC,MIB2,UBE2E2,KMT2E,TRIM11,PTP4A3,UBE2Q1,CSNK2A1,UBE2Z,SIRT2,USP48,FKBP2,MAPK14,BIRC2,RNF103,UBLCP1,ZER1,ABL2,FANCL,CDC42,ATG3,SRI,JOSD1,FGFR1OP2,ARID4A,CARM1,TIMM50,SRPK2,PTPRK,CDC37,PLK1,PTPN18,LAP3,RBX1,APH1A,VHL,TLK1,RIOX2,WDR82,UBE2V1,BRCA1,KMT2C,STK17B,USP21,CHD3,PPM1G,CAB39,BAZ1B,ADAM9,STK11,CHEK2,VPS4A,ROCK1,GALNT10,OSGEPL1,CAPN1,UBE2D3,RMND5A,UFC1,PCSK7,CDK13,ADCK5,PPP3CB,PM20D2,XPNPEP3,QSOX2,RHBDD1,DTL,C1GALT1,UBE2Q2,MED10,PPIL2,UBE3C,ZRANB1,LRSAM1,CSNK1G3,PSMA1,EIF2AK1,MAP4K3,UBE4B,SYVN1,METTL22,STYXL1,ZDHHC3,DAPK3,MASTL,GALNT2,KLHL15,SIAH2,PRMT7,ZDHHC7,CTSA,RBBP4,CCNB2,RNF114,USP7,PRKAB1,ASH1L,CYLD,MPHOSPH8,TRAF7,TMX4,NSD3,DUSP22,LYN,USP5,SEC11A,PDK2,MDM2,PSMA6,KMT5C,PPME1,PIN1,PPP6C,PARL,MINPP1,PDIA6,CTDSP2,SAP30L,HTRA2,SPSB3,PRPF19,RLIM,KDM3B,PPIF,BIRC3,PSMA8,PGGT1B,PPT1,RNF25,PPIE,PSMB7,MTMR6,NLN,KDM1B,MBD3,PEF1,USP36,RHBDF2,IDE,CLK3,FASTK,STK38,UHRF2,FKBP5,USP11,LTA4H,MAPK1,SMURF1,USP53,PPP2R2D,CBX4,CTDP1,TRIP12,CASP6,KLHL21,SHPRH,EYA1,SCYL1,TMX3,CDK11B,CSNK1A1,SCYL2,SPPL2A,PTPN2,FASTKD3,HERC3,IRF4,FGFR3,CTSS,GRK2,KLHL20,CWC27,KMT5A,PPIG,TANK,ZDHHC13,FBL,RNF5,CAMK2G,B3GALT6,CSNK1G2,ZDHHC18,ADAM17,HEMK1,PRKDC,MIER1,RCOR1,RFFL,PPWD1,PRMT2,MEN1,CDK11A,MAPK3,MTMR3,CTSL,FBXO41,PDCD6,NEK1,GOLGA7,BIRC5,KBTBD7,DTX4,KMT2B,USP20,SPCS3,PREPL,PLOD3,RPS6KC1,UBE2C,HIPK3 |
| 3.524e-06 | -12.56 | HSPH1 (heat shock protein family H (Hsp110) member 1) | protein interactions | 10808 | 96 | 34 | 17029 | 2761 |
ZNF207,USP7,CYLD,ADD1,UGP2,VAV2,CSNK2A1,USP39,DNAJB1,XPO7,CEP104,HUWE1,DPYSL2,TARDBP,TAGLN2,TP53BP2,ATF2,CFL1,CARM1,TERF2,CCT2,CUL3,EZR,NFATC2,DNAJA1,BRCA1,MCM2,HSPA4,CHD3,PPM1G,DNAJC17,USP11,TERF1,FAF1 |
| 3.533e-06 | -12.55 | nuclear periphery | cellular component | GO:0034399 | 131 | 40 | 18223 | 2701 |
MBD1,NCOR2,DNMT3A,ATXN3,THOC1,PHB2,CXXC1,CENPF,GMCL1,EBNA1BP2,BLM,LMNA,NUP205,HNRNPA2B1,PSMA6,AHCTF1,SMC3,CLIC4,PPIG,AKAP8,NUP107,ZNF326,TNPO2,NUP153,OGG1,HNRNPM,CFL1,MORC3,TELO2,PSPC1,NARF,ATXN1,MEN1,MATR3,NSMF,PML,RNASEL,RUVBL2,YY1,IPO4 |
| 3.536e-06 | -12.55 | GSE36476_CTRL_VS_TSST_ACT_16H_MEMORY_CD4_TCELL_OLD_DN | MSigDB lists | GSE36476_CTRL_VS_TSST_ACT_16H_MEMORY_CD4_TCELL_OLD_DN | 194 | 54 | 17377 | 2626 |
KIF3B,LYRM4,TXN,GNPDA1,TAP1,UCK2,TKT,EBNA1BP2,CLCC1,RMI1,IRF4,ERH,PSMD2,TNS3,HOMER1,GART,IARS,GOT2,DAPK1,ATP6V0A2,CYC1,GEMIN4,TALDO1,SEH1L,ZNF189,PTPRK,GINS1,PPAN,TXNL1,TIMM8B,CREG1,MRPL12,PSMG1,GORASP2,BMS1,TARS,UTP20,RAD51C,SLCO4A1,KEAP1,STT3A,ACOX1,CORO1C,STAT1,MLYCD,LY75,NUP62,ATF6,PITRM1,PGAM1,PDCD11,TUBB,BYSL,SSRP1 |
| 3.544e-06 | -12.55 | LAMP2 (lysosomal associated membrane protein 2) | protein interactions | 3920 | 88 | 32 | 17029 | 2761 |
EWSR1,MTX3,FAM118B,CHD1L,SF3B6,CDC6,TAZ,GUF1,LYN,PDXDC1,SFXN5,RHEB,SUB1,RAB18,EPRS,MDM2,PCNA,NEK6,JAK1,SAFB,BDH1,PDS5B,IMPDH1,ATP6V0A2,XRCC3,CTSA,RBBP4,NR2F2,GPD1L,TUBB,HP1BP3,PRPF19 |
| 3.552e-06 | -12.55 | energy derivation by oxidation of organic compounds | biological process | GO:0015980 | 222 | 60 | 17256 | 2622 |
COX15,COX5B,NDUFA5,NDUFV2,NDUFS1,PPP1R2,SUCLG1,NDUFB6,UGP2,NDUFAF2,UQCR10,MECP2,MDH2,SLC25A12,NDUFA4,COX4I1,CYCS,GYG1,SDHA,NDUFS7,NDUFS4,PPP1R3B,FASTKD3,MTFR1L,NDUFV1,NDUFA2,NDUFB4,IL6ST,CS,SUCLG2,NDUFB9,NDUFS8,CYC1,NDUFA3,PHKG2,RB1CC1,AKT2,COQ10B,IDH3A,MTFR2,TBRG4,ADSL,OGDH,NDUFA7,NDUFB1,TAZ,POLG2,GNAS,SDHB,CAT,RPS27A,COX7A2L,NDUFA11,COX8A,COX5A,DHTKD1,MDH1,UQCRH,NDUFS5,IDH3B |
| 3.553e-06 | -12.55 | chromosome, telomeric region | cellular component | GO:0000781 | 159 | 46 | 18223 | 2701 |
NSMCE4A,THOC1,SMC6,ORC1,SIRT2,BLM,CDC73,WRNIP1,TERF2IP,HNRNPA2B1,RPA2,PCNA,SP100,MCM5,MSH2,NABP2,NABP1,H2AFY,PTGES3,ORC3,TERF2,TELO2,ERCC1,PRKDC,WDR82,DCLRE1C,MEN1,MCM2,GAR1,RPA1,XRCC5,DOT1L,CBX3,UPF1,NSMCE2,PML,H2AFX,XRCC3,CHEK2,H3F3A,CDK2,POT1,TERF1,PURA,RAD51D,DDB1 |
| 3.556e-06 | -12.55 | spliceosomal snRNP complex | cellular component | GO:0097525 | 62 | 24 | 18223 | 2701 |
SART1,SNRNP200,SNRPB,SF3B1,SF3B6,LSM8,PRPF3,SNRPD3,PRPF39,TXNL4A,LUC7L,SF3A2,SNRPA,PRPF18,SF3B2,DDX23,LSM6,LUC7L3,EFTUD2,PRPF4,SNRPG,WDR62,SNRNP70,LUC7L2 |
| 3.574e-06 | -12.54 | adenyl ribonucleotide binding | molecular function | GO:0032559 | 1502 | 293 | 17224 | 2647 |
ABCC10,TAP1,DHX8,GLUD1,UBE2I,EEF2K,KIFC1,CDK5,NEK6,ATP13A3,PDS5B,SUCLG2,MAST2,PLK3,RHOBTB3,AKT2,PBK,KIF15,MKI67,DDX20,SMC2,AURKB,MCM2,RFC2,MAP3K4,MKNK1,KIF18B,LIMK1,MYO18A,RNASEL,LONP2,PFKP,DDX42,DDX58,HSPH1,RECQL,CHTF18,TRIO,PRKAA1,DHX9,RRM1,CERK,KIF23,TOP2B,EIF2AK4,DDX56,SMC3,MCM5,CTPS1,MSH2,DAPK1,RTCB,PIKFYVE,PHKG2,UBE2QL1,CARS2,DDX28,COQ8A,MAPKAPK3,DHX29,PGS1,PIP4K2C,PKM,ABCF1,MAP2K2,CCT8,PI4K2A,XRCC5,EPRS,NSF,CSK,CSNK1G1,DCK,QARS,ACLY,MAP3K5,CDK2,NRBP1,ACSF2,KARS,ABCA3,TP53RK,RPS6KA1,RAF1,CHD1L,KIAA0232,ACTR3,OLA1,TPX2,MYH9,PRKACA,CBWD5,FLAD1,PRKD3,ATP2A2,UBA5,ADCY9,CLCN6,TAP2,AQR,CDK12,ADCY7,CCT2,ULK3,ATP13A1,TAOK1,MAP4K4,PFKFB3,GALK2,PKMYT1,DNAJA1,MAT2A,DHX57,DDX17,KIF2A,RAD51C,HSPA4,JAK1,HIPK2,CBWD1,PDXK,PPP5C,CSNK1D,DYNC1LI2,POLQ,PRPF4B,GALK1,TWNK,IP6K2,ATP5F1B,BLM,PMVK,PIP5K1C,SRXN1,CBWD2,GATC,TTLL12,MAP3K14,UBE2M,MSH6,SMC4,PDPK1,TK1,GUK1,DDX24,NEK7,BMS1,DDX39A,KIF11,MARK2,MYO1F,KIF18A,TTLL4,MAPK6,ASNA1,DDX5,DDX52,DDX47,UBE2E2,YTHDC2,MCCC1,UBE2Q1,UBE2Z,CSNK2A1,ABCB10,KIF2C,MAPK14,PAPOLA,ABL2,EIF4A3,TRMU,XRCC2,KIF22,ABCC5,SRPK2,PLK1,LARS,SNRNP200,HARS,TLK1,CDC6,STK17B,DHX15,CHD3,IARS2,BAZ1B,QRSL1,ACTB,STK11,CHEK2,VPS4A,ROCK1,PSMC1,SEPHS2,UBE2D3,CDK13,THRAP3,CHKA,UBE2Q2,KIF13B,ALDH18A1,N4BP2,CSNK1G3,ABCC1,NTPCR,AACS,ACSL3,MAP4K3,EIF2AK1,UBE4B,BBS12,DAPK3,MASTL,PSMC4,PRPS2,NLRC5,ATP5F1A,RUVBL2,MYO9A,EHD4,PMS2,UCK2,UCK1,SMARCA4,ORC1,CHKB,ATP6V1B2,TWF2,LYN,CHD1,MIEF1,FARSA,PDK2,IARS,NVL,KIF14,SCYL3,ACSL5,CLCN3,CGAS,RAD54B,ATP1A1,IDE,CLK3,DHX16,STK38,FASTK,XRCC3,MAPK1,ABCA1,RAD51D,KIF3B,NADSYN1,SHPRH,TOR3A,GNE,SCYL1,SMC6,MYO9B,CDK11B,CSNK1A1,SCYL2,PIP4K2A,WRNIP1,KIF5B,STARD9,FGFR3,GART,GRK2,DDX31,ABCD1,MYO5A,CAMK2G,CSNK1G2,HELB,PRKDC,BTAF1,ABCF2,ATP2C1,PRKAR1B,NADK2,PNPLA8,CDK11A,TARS,DDX23,HSPA1B,MAPK3,NEK1,UPF1,ATAD2,RPS6KC1,UBE2C,HIPK3 |
| 3.582e-06 | -12.54 | GCM_BMPR2 | MSigDB lists | GCM_BMPR2 | 77 | 28 | 17377 | 2626 |
WSB2,KIF3B,SNX27,PHF10,CLCN3,EXOSC6,ZNF84,TSPYL4,ADO,ACSL3,MAP4K4,WBP2,NCKAP1,MACF1,FOXO3,ZNF275,CAND1,DDX17,CRKL,DLG5,FBXO21,ASAP2,GOLGA7,MTMR4,VPS26B,PPIG,OAZ2,PREPL |
| 3.622e-06 | -12.53 | nuclear DNA-directed RNA polymerase complex | cellular component | GO:0055029 | 145 | 43 | 18223 | 2701 |
INTS2,POLA2,CTDP1,POLR2K,ZNF768,TAF6L,POLR3K,CDC73,GTF2F1,MED8,MED10,INTS7,INTS1,CTR9,INTS12,TAF5L,POLR1B,TCEA1,ZNRD1,GTF2H2,RPRD1B,ERCC1,POLR2I,RPRD1A,KAT2A,POLR2L,POLR2G,PRIM2,HELB,POLR2D,POLR3GL,RTF1,EDF1,TWISTNB,POLR2A,PRIM1,PAF1,TAF2,POLR2J,TBPL1,CRCP,TAF12,TAF6 |
| 3.638e-06 | -12.52 | Translation | REACTOME pathways | R-HSA-72766 | 162 | 50 | 10287 | 1696 |
RPS15,RPS2,RPLP2,SEC61G,EIF3D,GSPT2,RPL15,RPL11,SSR1,RPL23A,SEC11A,RPN1,EIF2S2,RPL17,RPN2,RPL19,EIF5,PABPC1,RPL22L1,EEF1D,SRP72,RPL29,EIF3L,RPL35,SEC61B,RPL8,RPL38,RPL6,RPS10,SSR2,RPS24,RPL27A,EIF4H,EIF3G,RPS9,RPSA,EIF3H,EIF3A,RPL36,EIF3K,RPL37,DDOST,RPL32,SEC61A1,RPS27A,RPS14,RPLP1,SPCS3,FAU,RPS26 |
| 3.640e-06 | -12.52 | V$MAX_01 | MSigDB lists | V$MAX_01 | 243 | 64 | 17377 | 2626 |
ZBTB10,MAX,DNMT3A,ATXN3,TAF6L,STMN1,GNB2,SSR1,CSDE1,PA2G4,PDK2,SUCLG2,CEP63,SLC26A2,DVL2,CCAR1,CFL1,SRP72,AATF,TOPORS,ODC1,EIF3A,MAT2A,EPB41,SUPT16H,HHEX,SMAD2,HPS5,MRPL27,CLN3,NDUFS1,RPS2,SUMF1,MXD4,RLF,FOXO3,TFRC,TFAP4,FAM192A,SMC3,SLC38A5,PRDM4,MRPL40,PABPC1,ANKHD1,RBM15B,NUDC,AMPD2,PHF20L1,LONRF3,SIGMAR1,C16orf72,ILF3,UBE4B,PICALM,AKAP1,GNAS,ADSS,SYNCRIP,CSK,ASNA1,TCOF1,ATP6V1C1,RAB3IL1 |
| 3.661e-06 | -12.52 | PID_E2F_PATHWAY | MSigDB lists | PID_E2F_PATHWAY | 73 | 27 | 17377 | 2626 |
TK1,KAT2A,MYBL2,RRM1,E2F3,RRM2,MCL1,CDC6,BRCA1,ORC1,TRIM28,CDKN2C,RB1,CCNA2,RBL1,TFE3,E2F4,TFDP1,E2F1,CDKN1B,RBBP4,YY1,TFDP2,CDK2,E2F2,CDKN2A,RYBP |
| 3.670e-06 | -12.52 | REACTOME_ANTIVIRAL_MECHANISM_BY_IFN_STIMULATED_GENES | MSigDB lists | REACTOME_ANTIVIRAL_MECHANISM_BY_IFN_STIMULATED_GENES | 65 | 25 | 17377 | 2626 |
DDX58,NUP188,RAE1,NUP54,NUP155,IRF3,EIF4G2,NUP205,ISG15,MAPK3,KPNA4,KPNA1,NUP210,JAK1,EIF4A3,RPS27A,PIN1,STAT1,NUP107,NUP62,NUP153,KPNA2,NUP85,AAAS,SEH1L |
| 3.673e-06 | -12.51 | V$ELK1_01 | MSigDB lists | V$ELK1_01 | 253 | 66 | 17377 | 2626 |
PRKAB1,GGNBP2,TRAF7,CAST,RAC1,EBNA1BP2,BCL2L1,POMP,CNTROB,MAPK14,GIT2,TMEM161B,C14orf119,PHC2,SEC11A,SHC1,UTP18,PPME1,MTPN,ZNF800,SP3,ARHGDIB,NUP155,HERPUD2,SOX4,AP4E1,NECAP2,EIF3K,PAF1,WAS,TBC1D17,RWDD4,UQCRH,PRPF4,GEN1,MRPL13,UBE2D3,ZCCHC9,PHB2,ANKH,UBXN1,UFC1,SMC6,AKT1S1,PPP3CB,DNAJB9,MCTS1,VASP,PPIG,CAPZA1,MRPL54,TAGLN2,CITED2,CNOT6L,MTX2,ANKHD1,EIF3L,TIMMDC1,RXRB,TMEM127,FNTA,FAM110A,ELMO1,ZRANB2,PDLIM5,THAP5 |
| 3.713e-06 | -12.50 | GO_NEGATIVE_REGULATION_OF_CELLULAR_AMIDE_METABOLIC_PROCESS | MSigDB lists | GO_NEGATIVE_REGULATION_OF_CELLULAR_AMIDE_METABOLIC_PROCESS | 120 | 38 | 17377 | 2626 |
UNK,PRKAA1,TIA1,EIF2AK4,METTL3,RBM4,SRRT,CNOT3,PAIP2,HNRNPA2B1,EIF4A3,METTL14,DAPK1,CNOT6L,STAT3,BTG2,ILF3,CIRBP,EIF2AK1,PRKRA,FXR1,DAPK3,EPRS,TSC1,UPF1,EIF4ENIF1,SMAD2,SYNCRIP,DGCR8,HNRNPR,PML,CNOT6,CLU,SMAD1,CPEB2,PURA,TOB1,RNF139 |
| 3.713e-06 | -12.50 | GO_GOLGI_STACK | MSigDB lists | GO_GOLGI_STACK | 120 | 38 | 17377 | 2626 |
RAB14,GOLIM4,GOLPH3L,TMBIM4,B4GALT5,B4GALT1,TMED3,B4GALT4,BCAP31,HLA-A,RAB21,ASAP2,FUT8,NSFL1C,TMED2,B3GALT6,PLK3,NAGPA,MOB4,USO1,TMEM115,APH1A,STX16,GOSR1,NUCB1,GALNT2,GOLGA7,GOLGA2,NSF,GOLGA8A,ARAP1,VCPIP1,CANT1,ST3GAL2,B4GALT3,CLN3,CHPF2,B4GALT2 |
| 3.719e-06 | -12.50 | vesicle targeting | biological process | GO:0006903 | 85 | 30 | 17256 | 2622 |
USO1,TRAPPC9,GORASP1,CUL3,MCFD2,RAB1A,PEF1,PSEN1,SEC16A,ANKRD28,SEC31A,CD59,SEC23IP,PDCD6,GOLGA2,NSF,TMED10,SEC24C,SNAP29,SNAP23,PPP6C,EXOC4,LMAN1,PPP6R3,TFG,PPP6R1,TMED2,CSNK1D,PREB,STARD3NL |
| 3.720e-06 | -12.50 | GTPBP4 (GTP binding protein 4) | protein interactions | 23560 | 121 | 40 | 17029 | 2761 |
NIFK,DDX47,NOP2,SUZ12,MECP2,EBNA1BP2,BRIX1,RBM4,LYAR,DDX56,RBM34,NOC2L,RPF2,FBL,ZC3H3,SRPK2,NOL12,PPAN,IFRD1,STAU1,DDX24,ZNF512,RPL6,UTP3,PRKRA,KIF11,MAK16,CAND1,RPL36,NSA2,MRPL2,DGCR8,TBL3,RPS14,DDX5,RRS1,NMD3,ZC3HAV1,IFI16,GPATCH4 |
| 3.720e-06 | -12.50 | TAGLN2 (transgelin 2) | protein interactions | 8407 | 121 | 40 | 17029 | 2761 |
HSPH1,TXN,RAE1,UFC1,TKT,ATP5F1B,FKBP2,SPR,EIF1B,DUSP22,CDC73,APP,LMNA,RPA2,FKBP1A,CLIC4,PIN1,DUT,AHCYL1,ATF2,CFL1,GPX4,VHL,EZR,UBE2V1,NUTF2,TOMM40,MCM2,RPA1,EPB41,HSPA4,TXNDC16,BRD2,HINT1,CDK2,LTA4H,UBE2C,IGBP1,PGAM1,SSSCA1 |
| 3.742e-06 | -12.50 | GSE3982_EOSINOPHIL_VS_MAST_CELL_DN | MSigDB lists | GSE3982_EOSINOPHIL_VS_MAST_CELL_DN | 180 | 51 | 17377 | 2626 |
KCTD7,NDUFA5,GNPDA1,CAST,RRM1,ZFYVE21,CHCHD2,PARN,HMG20A,DDRGK1,PCNA,PSMD1,NDUFB4,INTS7,ZNHIT6,GRSF1,MRPL34,AKR1B1,RPN2,FBL,DNMT1,FAM171A1,NIPSNAP1,RYBP,POLR2I,DCAF6,ABCF2,VDAC2,SEPT8,MRPL16,GORASP2,UBE4B,NDUFA7,UTP3,SOX4,CCT8,PDHX,CLNS1A,OPTN,RPA1,STOML2,RPL36,DTWD1,DAP3,GALNT2,WDR11,IARS2,CEBPG,MDH1,COPS6,TUBB |
| 3.742e-06 | -12.50 | GSE29618_PRE_VS_DAY7_FLU_VACCINE_MONOCYTE_DN | MSigDB lists | GSE29618_PRE_VS_DAY7_FLU_VACCINE_MONOCYTE_DN | 180 | 51 | 17377 | 2626 |
MMACHC,IER2,ZBTB10,REPS2,CHERP,C1orf112,UBR2,DCTN2,STRN4,NENF,SYNRG,FANCI,WWP2,PHC2,IARS,MEGF8,GPATCH1,RPAP1,TRA2B,CDC25B,SCYL3,ZNF189,CPNE1,ZFP64,ATP13A1,HEMK1,ZNF84,BTG2,METTL5,CRNKL1,MEN1,NDUFB1,PRMT2,ZFAND5,KLF6,MTR,ARF4,SRSF1,TMEM184C,GALNT2,MID1IP1,OSBPL8,PSMD3,PROSER1,CAB39,KPNA2,ATP6V1C1,RBBP4,PDLIM5,ZNF146,S100PBP |
| 3.742e-06 | -12.50 | GSE17721_POLYIC_VS_CPG_6H_BMDC_DN | MSigDB lists | GSE17721_POLYIC_VS_CPG_6H_BMDC_DN | 180 | 51 | 17377 | 2626 |
ZNF296,TMED7,TP53RK,SMAP1,HJURP,RWDD1,THOC1,SEC61G,SRGN,STRN4,SLC4A2,PABPC4,RRP36,EEF2K,MOAP1,CAPN2,LYAR,FGFR3,NRF1,SAR1A,RALB,UTP18,ATP13A3,PTPN11,SEPT11,ANAPC7,EIF5,RPL22L1,TMBIM1,TMX1,ABCC1,PPIF,ADAM17,MAPRE2,AATF,PGS1,BTG2,RABIF,ARHGEF12,CYFIP2,GFER,STK17B,PICALM,RHOB,MAT2A,RBM38,HGS,ETS2,GADD45B,NMD3,IPO4 |
| 3.758e-06 | -12.49 | protein localization to chromosome | biological process | GO:0034502 | 57 | 23 | 17256 | 2622 |
PLK1,MRNIP,CTCF,AURKB,SPDL1,MIS12,XRCC5,RPA1,TERF2IP,LEMD2,RPA2,RB1,NABP2,H2AFY,RUVBL2,CENPT,CHMP7,SLF1,POT1,SLF2,SGF29,CARM1,TERF2 |
| 3.766e-06 | -12.49 | SCHLOSSER_MYC_AND_SERUM_RESPONSE_SYNERGY | MSigDB lists | SCHLOSSER_MYC_AND_SERUM_RESPONSE_SYNERGY | 32 | 16 | 17377 | 2626 |
SRM,FARSA,DDX28,POLR2I,SCAMP3,MTA1,MRPL12,KHSRP,ARFIP2,SEPT11,FRAT2,NCLN,TAGLN2,NDUFS5,TOMM40,SNRPA |
| 3.766e-06 | -12.49 | FARMER_BREAST_CANCER_CLUSTER_2 | MSigDB lists | FARMER_BREAST_CANCER_CLUSTER_2 | 32 | 16 | 17377 | 2626 |
CCNA2,ATAD2,RB1CC1,ASPM,PRKDC,CEP55,PTTG1,PRC1,TPX2,KIF15,NUSAP1,RRS1,CCNB2,NCAPG,KIF11,RAD54B |
| 3.790e-06 | -12.48 | MAK16 (MAK16 homolog) | protein interactions | 84549 | 65 | 26 | 17029 | 2761 |
NOL12,RPS15,ZCCHC9,NOP2,DDX24,POLK,GTPBP4,SMC6,CSNK2A1,EBNA1BP2,BRIX1,GAR1,KRR1,NSA2,MDM2,RPL32,NVL,DGCR8,RPS27A,RBM34,NOC2L,RPF2,FTSJ3,ZC3HAV1,IFI16,GPATCH4 |
| 3.831e-06 | -12.47 | Vibrio cholerae infection | KEGG pathways | ko05110 | 51 | 22 | 7161 | 1149 |
SEC61B,SEC61G,ERO1A,ATP6V0A1,ARF1,KCNQ1,ATP6V1B2,PRKACA,GNAS,ATP6V0B,ATP6V1D,SEC61A1,ADCY9,ATP6V0A2,ATP6V0C,ACTB,ATP6V1C1,SLC12A2,ATP6V0E1,ATP6V0D1,ATP6V1G1,KDELR1 |
| 3.831e-06 | -12.47 | Vibrio cholerae infection | KEGG pathways | hsa05110 | 51 | 22 | 7161 | 1149 |
SEC61B,SEC61G,ERO1A,ATP6V0A1,ARF1,KCNQ1,ATP6V1B2,PRKACA,GNAS,ATP6V0B,ATP6V1D,SEC61A1,ADCY9,ATP6V0A2,ATP6V0C,ACTB,ATP6V1C1,SLC12A2,ATP6V0E1,ATP6V0D1,ATP6V1G1,KDELR1 |
| 3.841e-06 | -12.47 | MARTENS_BOUND_BY_PML_RARA_FUSION | MSigDB lists | MARTENS_BOUND_BY_PML_RARA_FUSION | 413 | 97 | 17377 | 2626 |
UBL3,TOMM20,GPR132,RWDD1,ARID2,POC1A,RPS6KA1,TMEM41B,UCK2,ENSA,MYH9,LYN,GNB2,CDK5,SEC11A,APLP2,NUP210,NEK6,RCSD1,PPCDC,MRPL34,DNM2,FGFR1OP2,KCNAB2,DCTN1,CSTF1,TIMP2,TMEM115,ANKRD33B,GALK2,NUTF2,MEF2D,RPS9,RHBDF2,DOT1L,PSMD3,LMBR1,ATP6V0C,ST3GAL2,ANP32E,SCARB1,KLHDC4,AKNA,OAZ1,ANXA11,HIVEP3,NCOR2,CDS2,TM9SF4,GGA1,CUTA,B4GALT1,CTCF,KLF13,LETMD1,NDUFA4,GTF3A,MYO9B,SLC35B1,PMF1,BLM,PSMD9,TUBGCP2,FERMT3,KRI1,VASP,PTEN,MCM5,BANF1,FAM89B,ARHGEF2,TAGLN2,ZNF710,NUP85,HNRNPM,CAMK2G,ABHD2,TNFAIP3,GALC,GBA,WDR81,TOMM40,MPG,MYO1F,TPD52L2,CSK,WNT5B,TFDP1,ARAP1,DCAF11,SLC25A19,DDX5,PSAP,MBD6,ZMIZ1,DEF6,NUDT3 |
| 3.843e-06 | -12.47 | CDK3 (cyclin dependent kinase 3) | protein interactions | 1018 | 54 | 23 | 17029 | 2761 |
CCNC,AKT2,CDT1,E2F3,CUL1,CCNB1,APP,CDK5,RB1,CCNA2,HSPA4,TFDP1,E2F1,CDKN1B,FKBP5,CDC25B,CABLES2,COPS6,CDK2,ARRB2,E2F2,CABLES1,CDC37 |
| 3.843e-06 | -12.47 | POLA1 (DNA polymerase alpha 1, catalytic subunit) | protein interactions | 5422 | 54 | 23 | 17029 | 2761 |
POLA2,PRIM2,HELB,RAE1,WDHD1,KRAS,CDC6,MCM2,CCNB1,GINS4,RPA1,XRCC5,PRIM1,PPP2CA,RPA2,RB1,PCNA,CCNA2,POLE,SOCS6,RBMS1,CDK2,PURA |
| 3.843e-06 | -12.47 | Max (Max protein) | protein interactions | 17187 | 54 | 23 | 17029 | 2761 |
SEC61B,FOXK1,MIER1,RPL6,NUF2,MXD4,FXR1,MRPL19,TARS,SAP130,BRMS1,GNAS,PFDN5,PRDX3,MBD2,PRDX5,TFDP1,MRPL27,OGT,FKBP5,SINHCAF,PDF,SAP30 |
| 3.860e-06 | -12.46 | GSE2706_UNSTIM_VS_2H_LPS_AND_R848_DC_UP | MSigDB lists | GSE2706_UNSTIM_VS_2H_LPS_AND_R848_DC_UP | 166 | 48 | 17377 | 2626 |
PIGM,PRPF38B,TP53RK,THOC1,KDM4A,PHF23,TSC22D3,KIAA0232,PDCD7,ZNF275,TMEM179B,ASPHD2,RFWD3,CEP104,ZNF420,ZNF449,ZNF302,MTMR4,TTC9C,CDKN1B,RNF26,ZNF770,SOCS5,CSTF1,DDX28,ZNF500,FAM118B,RNF25,TIGD5,ZBED5,LNX2,FRAT2,USP10,ITM2A,CBFA2T2,BUD13,POLG2,LSG1,FADD,MTMR3,HHEX,ITPRIPL1,EIF4ENIF1,ZNF689,BAZ1B,MRFAP1L1,TRIM32,ZNF830 |
| 3.863e-06 | -12.46 | CHAUHAN_RESPONSE_TO_METHOXYESTRADIOL_DN | MSigDB lists | CHAUHAN_RESPONSE_TO_METHOXYESTRADIOL_DN | 94 | 32 | 17377 | 2626 |
H2AFZ,TNFAIP3,ADD1,PHB2,SEC61G,BTG2,RAF1,COPE,WBP2,MKI67,MCL1,ARHGDIB,CYFIP2,UBE2I,AP3S1,FOXO3,DDX17,EIF3K,GNAS,NUCB1,NAP1L1,SLC1A4,DDOST,PDLIM1,ARPC5,ARL6IP1,MDH1,BTF3,LTA4H,PABPC1,PCBP2,TUBB |
| 3.871e-06 | -12.46 | peptidyl-lysine methylation | biological process | GO:0018022 | 81 | 29 | 17256 | 2622 |
ASH1L,KMT2E,SUZ12,CXXC1,EHMT1,NSD3,WDR82,RTF1,EZH1,WDR5,KMT2C,METTL22,MEN1,RLF,KDM3A,DOT1L,TET3,IRF4,KMT5C,SUV39H2,KMT5A,SETD3,CAMKMT,OGT,ZNF335,KMT2B,CTR9,BEND3,ARID4A |
| 3.899e-06 | -12.45 | RBM14 (RNA binding motif protein 14) | protein interactions | 10432 | 117 | 39 | 17029 | 2761 |
SUZ12,SF3B1,RBM8A,CUL1,TOP2B,THRAP3,UBE2I,SEC16A,WWP2,RPA2,GTSE1,ABI1,FTSJ3,HNRNPM,SRSF10,HP1BP3,PRPF19,SRSF11,RNPS1,CUL3,DDX20,EIF2AK1,BRCA1,MCM2,MATR3,SRSF1,CAND1,XRCC5,RPA1,SDHB,RBM25,HNRNPR,MFAP1,RBMX,COPS6,RRS1,POT1,IFI16,SSRP1 |
| 3.900e-06 | -12.45 | GSE3982_NEUTROPHIL_VS_TH1_DN | MSigDB lists | GSE3982_NEUTROPHIL_VS_TH1_DN | 185 | 52 | 17377 | 2626 |
ATXN3,FOXM1,MUM1,PTTG1,STARD7,NENF,GTF3A,SDF2L1,FAM136A,LYRM2,TUBGCP2,KIFC1,CTNNBL1,ATP2A2,UTP18,INTS7,GRSF1,SRI,MRPL34,COPS7B,TTC4,UBE3C,ILKAP,SEH1L,NUDC,NOL12,TDP1,ABCF2,RPL8,RANGAP1,BRCA1,ESYT1,MPG,BORA,ODC1,CBFB,FANCE,FADD,AKAP1,MAP3K4,DTWD1,DDOST,DGCR8,NIP7,NEIL3,PRPS2,C1orf109,QRSL1,CD81,HEXA,HDAC2,DDX52 |
| 3.900e-06 | -12.45 | GSE33425_CD161_HIGH_VS_INT_CD8_TCELL_DN | MSigDB lists | GSE33425_CD161_HIGH_VS_INT_CD8_TCELL_DN | 185 | 52 | 17377 | 2626 |
GALK1,GCLM,PKP4,TXN,RWDD1,SEC61G,UCK2,TKT,KIF23,RACGAP1,AGFG1,POMP,BLM,BRIX1,SPR,AP3S1,BZW2,EBP,RBM17,FKBP1A,PCNA,EXOSC7,VMP1,DAD1,FUT8,OSTF1,OSTC,PPA1,IMPA2,EMB,SELPLG,METTL5,MKI67,GMFB,POLR2D,CDC6,PSMB3,ASF1B,PRIM1,MYO1F,RPA1,AMZ2,GALNT2,VPS26B,QARS,DBI,CHMP4B,SASS6,RPS26,PDCD4,TUBB,PFKP |
| 3.900e-06 | -12.45 | GSE3337_CTRL_VS_16H_IFNG_IN_CD8POS_DC_DN | MSigDB lists | GSE3337_CTRL_VS_16H_IFNG_IN_CD8POS_DC_DN | 185 | 52 | 17377 | 2626 |
POLA2,SCAMP3,GGA1,TMEM41B,RAF1,PDAP1,CDT1,CDK2AP2,TAP1,PMF1,EIF1B,IFT27,LIN9,NDUFV1,DAD1,SIVA1,RAD23B,BUD31,TPST1,TAP2,RNASEH2A,STAT3,FRMD8,NUP85,PPA1,LYPLA2,TMEM160,POLR2L,SEPT9,KAT7,CPOX,MFNG,RNPS1,WDHD1,PFKFB3,PITPNB,IL12RB1,TOMM40,MCM2,OGFR,CYFIP2,MAP3K4,FAM110A,PML,BCL7C,PQBP1,AP1S1,NUP62,DVL1,PLOD3,CAPN1,NUDT3 |
| 3.900e-06 | -12.45 | GSE20754_WT_VS_TCF1_KO_MEMORY_CD8_TCELL_UP | MSigDB lists | GSE20754_WT_VS_TCF1_KO_MEMORY_CD8_TCELL_UP | 185 | 52 | 17377 | 2626 |
NAT14,UBE2D3,TBC1D12,ARID5A,DLGAP4,LAMTOR3,BCL2L1,KCMF1,PAIP2,MOAP1,PTPN2,ABL2,MEX3C,KLF16,ANXA5,CHTOP,MRPL32,YTHDC1,SHOC2,ERCC1,ADAM17,TNFAIP3,BIRC3,MAPKAPK3,COQ10B,MAP4K4,WBP2,GTPBP4,PIP4K2C,EAF2,RAB1A,KLF6,ARF4,HSPA1B,AMZ2,HLA-B,ETS2,CCDC86,PDRG1,DUSP3,ZNF330,PSMD8,MAFK,GADD45B,ZNF436,CEBPG,DUSP11,ATP6V1C1,ZNF830,SMAD4,CWC25,ADNP2 |
| 3.900e-06 | -12.45 | GSE22886_NAIVE_BCELL_VS_BLOOD_PLASMA_CELL_DN | MSigDB lists | GSE22886_NAIVE_BCELL_VS_BLOOD_PLASMA_CELL_DN | 185 | 52 | 17377 | 2626 |
GLT8D1,CDS2,MAGEH1,LIME1,GOLPH3L,TMEM184B,MRPS15,MRPL39,MAGED1,MOGS,RRM1,CLCC1,NANS,SLC35B1,FAM136A,NCAPG,SAC3D1,CFLAR,EBP,MAN1A1,PSMD1,FUT8,RRBP1,LMAN1,SPTSSA,MVP,TFG,LRRC59,KDELR1,PPIF,COPS8,MLEC,NASP,KLF10,MRPL12,BOLA1,SMC2,CADM1,SHCBP1,KIF11,MAGED2,TRAM2,EPRS,PLAA,TPP2,ACOX1,ACAT1,IMPDH1,MRPL13,CCNB2,NRBP1,DDB1 |
| 3.900e-06 | -12.45 | GSE339_CD4POS_VS_CD8POS_DC_IN_CULTURE_UP | MSigDB lists | GSE339_CD4POS_VS_CD8POS_DC_IN_CULTURE_UP | 185 | 52 | 17377 | 2626 |
UBE2D3,HSPH1,SARNP,SF3B1,MDH2,HNRNPUL2,RAC1,ANKH,ARGLU1,RGS2,STAM,PIP4K2A,MAN1A1,ANKRD28,NUDT19,RB1,RAP1A,NUS1,PSMA6,ZKSCAN1,RAD23B,RAB4A,PPP6C,MDFIC,CHTOP,CNOT6L,MTX2,S100A6,DRAM2,MSH6,NUDC,CSTF1,SP3,POLR2G,KAT7,KRAS,MAP7D1,ICAM2,MATR3,FKBP3,FADD,RHOB,CBX3,CSK,PSMD8,TPP2,SIAH2,DDX5,SNRPG,RBBP4,LTA4H,RTN3 |
| 3.900e-06 | -12.45 | GSE41867_DAY6_EFFECTOR_VS_DAY30_MEMORY_CD8_TCELL_LCMV_ARMSTRONG_UP | MSigDB lists | GSE41867_DAY6_EFFECTOR_VS_DAY30_MEMORY_CD8_TCELL_LCMV_ARMSTRONG_UP | 185 | 52 | 17377 | 2626 |
HIVEP3,PNISR,GNPDA1,DCTN2,FAM76A,CIB1,ACAP1,ENSA,RRAGC,PXMP2,IP6K2,MAP1LC3B,MXD1,FERMT3,FBXO3,GNS,RAP1A,ZFYVE27,FAM76B,LRSAM1,PHKG2,ABI1,TERF2,NIPAL3,PPP3CA,BRD4,KIAA0040,PGGT1B,ZMYND11,BTG2,MEF2D,STX16,POLG2,PSMB9,EIF3H,NEU1,EIF3K,PFDN5,PLD3,DUSP3,CLK3,GLG1,COX8A,CLU,AKNA,DCAF5,ZC3HAV1,CAPN1,CSNK1D,TIGD2,S100PBP,ZBTB24 |
| 3.900e-06 | -12.45 | GSE3982_CENT_MEMORY_CD4_TCELL_VS_TH2_DN | MSigDB lists | GSE3982_CENT_MEMORY_CD4_TCELL_VS_TH2_DN | 185 | 52 | 17377 | 2626 |
C19orf53,FOXM1,SEC61G,MRPL39,CENPF,PTTG1,TKT,CSNK2A1,CHCHD2,BLM,NCAPG,GLRX3,HDDC2,NDUFS7,FANCI,CHKA,KIFC1,ATP2A2,GMEB1,TIMELESS,YBX1,RNASEH2A,SMC4,TIMM8B,NASP,MKLN1,TSTA3,CDC123,SNRPB,VDAC2,MRPL12,RRM2,EXOSC9,BRCA1,USP22,VDAC1,RFC2,YIF1A,KIF2A,TIMM13,MTHFD2,PRDX3,STT3A,BIRC5,PSMD3,NFIL3,XRCC3,CCNB2,ESPL1,TUBB,POLQ,SSRP1 |
| 3.900e-06 | -12.45 | GSE32986_CURDLAN_LOWDOSE_VS_GMCSF_AND_CURDLAN_LOWDOSE_STIM_DC_DN | MSigDB lists | GSE32986_CURDLAN_LOWDOSE_VS_GMCSF_AND_CURDLAN_LOWDOSE_STIM_DC_DN | 185 | 52 | 17377 | 2626 |
INTS2,HSPH1,MAX,RWDD1,MRPS2,ANKH,MON1B,UBE4A,SNRPD3,C19orf48,SNAPC4,SEC11A,LYAR,ERH,RRN3,SNUPN,EXOSC7,ATP2A2,CLCN6,NUP153,POLR1B,OSTC,EIF5,PPA1,SEH1L,ABCC1,AMPD2,SEPT9,PRRC2A,NOA1,AACS,PGS1,NOL8,NSUN2,UTP15,PSMG1,BMS1,TOMM40,KRTCAP2,ODC1,EML4,CCT8,TWISTNB,EPRS,ETS2,PFDN4,TBL3,RGL1,LTA4H,TRAF5,ZNF598,NUDT3 |
| 3.945e-06 | -12.44 | TRIM28 (tripartite motif containing 28) | protein interactions | 10155 | 294 | 78 | 17029 | 2761 |
COX15,UBE2E2,ZNF496,DNMT3A,SUZ12,MAGED1,SUMO2,ZNF416,CUL1,SMARCA4,ZNF267,CCNB1,UBE2I,STMN1,LYN,PCBP1,PARK7,MDM2,ZNF420,PPME1,TARDBP,DNMT1,HTRA2,CCT2,VHL,E2F3,CUL3,TOPORS,BRCA1,TRIM28,CHAF1A,PPP2CA,CDCA4,HNRNPR,CHD3,ZNF689,STAT6,E2F4,STAT1,H2AFX,ZNF268,CHEK2,H3F3A,ARRB2,SMURF1,ZNF720,UBE2D3,ZNF445,SRRT,HAUS2,LMNA,WRNIP1,RPA2,MEX3C,HUWE1,AHSA1,ZNF746,TTLL12,STAT3,STAU1,ZNF84,MTA2,RFXANK,CCT8,CBX3,CAND1,RPA1,HLA-B,PFDN5,SERTAD2,CCDC6,TFE3,E2F1,RUVBL2,ZMIZ1,CDK2,UBE2C,CDKN2A |
| 3.954e-06 | -12.44 | TTGCCAA,MIR-182 | MSigDB lists | TTGCCAA,MIR-182 | 304 | 76 | 17377 | 2626 |
WASF2,ADAM10,ANK3,RAC1,DAZAP2,MAP1LC3B,KCMF1,GIT2,KTN1,EPM2A,PAIP2,ATP2A2,TBC1D22A,JAZF1,EIF5,MCMBP,RPRD1B,CFL1,SLC39A9,SP3,TRIM8,TMEM115,SEPT9,GMFB,WIPF1,ATXN1,MEF2D,ARF4,EIF3A,VPS26B,LIMK1,GOLGA8A,CORO1C,OGT,SMAD1,DYNC1LI2,NUMB,PRPF4B,BCL2L12,PPP1R2,VAV2,FLOT1,KLF13,ARGLU1,DCUN1D4,FOXO3,PDXDC1,XPR1,VASP,ADD3,UBE2Q2,RIMS3,SS18L1,BCL2,UBE3C,CITED2,CNPY3,FAM171A1,KDELR1,TXNL1,ELL2,TACC1,SEPT7,FXR1,NAP1L1,ETS2,CDC27,ELMO1,SNAP23,EXOC4,PPP3R1,FAM122A,CNOT6,WIPI2,PREPL,TOB1 |
| 4.046e-06 | -12.42 | GSE17186_BLOOD_VS_CORD_BLOOD_NAIVE_BCELL_UP | MSigDB lists | GSE17186_BLOOD_VS_CORD_BLOOD_NAIVE_BCELL_UP | 190 | 53 | 17377 | 2626 |
GOLIM4,PARP12,TMBIM4,SESTD1,FAM129A,SRGN,ACTR3,PMF1,NOTCH2,TMED3,POMP,FKBP2,SYNRG,RAB11A,APP,ATP6V0B,RPN1,TNFAIP8,TPST1,ATP6V0A2,CLDND1,OSTC,RNF135,TMEM8A,MOB1A,LPCAT1,TMBIM1,TGFB1,ARHGAP17,EID1,RRM2,GALNT7,USP22,PTTG1IP,ARMC8,GFER,HAUS8,NUCB1,GOLGA7,HINT1,STT3A,HIPK2,MYO18A,CEP55,COX8A,SEL1L,E2F1,SLC22A23,PDLIM5,SLC25A39,DYNC1LI2,STARD3NL,TMEM131 |
| 4.046e-06 | -12.42 | GSE28726_NAIVE_CD4_TCELL_VS_NAIVE_NKTCELL_UP | MSigDB lists | GSE28726_NAIVE_CD4_TCELL_VS_NAIVE_NKTCELL_UP | 190 | 53 | 17377 | 2626 |
WSB2,RHOG,CHMP2A,CDS2,IMMT,FEZ2,HNRNPAB,URB2,DYNLL1,SRGN,CYCS,FKBP2,PNO1,CFLAR,IRF4,PRKD3,SUB1,HOMER1,VASP,UTP18,TXLNA,RPN2,SS18L1,RP2,AHCYL1,COPS8,POU2AF1,SP3,ADAM17,MAPRE2,MKLN1,HMGN4,GABPA,WDR1,AMD1,ACSL3,UTP3,EIF4G2,RAB22A,PRDX1,RHEB,CAND1,PPP2CA,MTHFD2,UAP1,LTBP4,SYNCRIP,CCDC6,HPS5,SNRPG,RRS1,RNF14,PGAM1 |
| 4.046e-06 | -12.42 | GSE360_L_DONOVANI_VS_B_MALAYI_LOW_DOSE_MAC_DN | MSigDB lists | GSE360_L_DONOVANI_VS_B_MALAYI_LOW_DOSE_MAC_DN | 190 | 53 | 17377 | 2626 |
MMACHC,NCOR2,TMEM184B,DAP,ACTR3,CDK2AP2,KLHL18,SLC29A1,BCL2L1,AP1B1,UBE2I,AP3S1,NDUFS7,VAV1,CLIC4,PDCD10,SHC1,SH3BP1,AHSA1,FAM89B,ANXA5,GNAI2,PPP6R1,SMC4,ENPP4,PTPN18,SEC61B,ACP2,TSTA3,CDC123,PPT1,ZNF202,VDAC2,USP10,GORASP2,SLC25A5,MACF1,RHEB,PAF1,ALG3,DDOST,POLR2J,GOLGA2,TMED10,DUSP3,DHX16,TAB2,SAFB,IMPDH1,USF2,PDCD11,ADAM23,ZBTB24 |
| 4.046e-06 | -12.42 | GSE21670_IL6_VS_TGFB_AND_IL6_TREATED_STAT3_KO_CD4_TCELL_UP | MSigDB lists | GSE21670_IL6_VS_TGFB_AND_IL6_TREATED_STAT3_KO_CD4_TCELL_UP | 190 | 53 | 17377 | 2626 |
POLA2,SKA3,CORO7,COPA,KDM4A,B4GALT5,TMEM41B,RAE1,DBF4,RRAGC,KIF23,JMJD6,GLUD1,PITHD1,CDC73,NUP205,CAPN2,PSMD1,MLX,MTMR4,DUT,LPIN2,TTC9C,ARL6IP1,YBX1,PCYT2,PHKG2,IFT46,NIPSNAP1,GINS1,POU2AF1,KLF10,POLK,CDC123,ELP4,NFATC2,SYVN1,ANLN,ARPC1A,TTC33,GINS4,POLE,HAGHL,C4orf46,NAA20,SASS6,PGAM1,LONP2,HRAS,TSPAN5,ANAPC4,ALS2,FAM72A |
| 4.052e-06 | -12.42 | GNF2_RFC3 | MSigDB lists | GNF2_RFC3 | 39 | 18 | 17377 | 2626 |
RFC3,H2AFZ,FOXM1,ASPM,RAD51AP1,RRM1,ADSL,SMC2,KIF11,FANCI,SUPT16H,CCNA2,BIRC5,TIMELESS,UBE2C,MSH6,SMC4,SSRP1 |
| 4.062e-06 | -12.41 | ATPase activity, coupled | molecular function | GO:0042623 | 381 | 92 | 17224 | 2647 |
DDX47,ABCA3,DYNLL1,ABCC10,CHD1L,YTHDC2,TAP1,MYH9,DHX8,SMARCA4,ABCB10,ATP6V1B2,CHD1,ATP6V0B,ATP2A2,EIF4A3,KIF14,XRCC2,ATP13A3,TAP2,DNAL4,ABCC5,ATP6V1G1,SNRNP200,ATP13A1,RFC3,ATP6V0A1,DDX20,PBRM1,RFC2,DHX15,DHX57,RAD54B,DDX17,RAD51C,HSPA4,ATP1A1,RAD18,KIF18B,CHD3,DHX16,ATP6V0C,XRCC3,VPS4A,PSMC1,ATP6V0E1,ABCA1,LONP2,RAD51D,DDX42,POLQ,KIF3B,RECQL,HSPH1,CHTF18,DHX9,TOP2B,ATP5F1B,BLM,KIF5B,DDX56,MSH2,ATP6V0A2,ABCD1,DDX31,GTF2H2,ATP6V0D1,MSH6,ABCC1,DDX28,DDX24,DHX29,HELB,ATP2C1,DDX39A,KIF11,CCT8,HSPA1B,PSMC4,DDX23,XRCC5,UPF1,ATP6V1D,KIF18A,ATP5MC3,NSF,DDX5,RUVBL2,ATP5F1A,RBBP4,ATP6V1C1,DDX52 |
| 4.070e-06 | -12.41 | LI_AMPLIFIED_IN_LUNG_CANCER | MSigDB lists | LI_AMPLIFIED_IN_LUNG_CANCER | 171 | 49 | 17377 | 2626 |
MIF,RPS2,NQO1,DAP,MAGED1,SUMO2,NACA,CDK2AP2,TKT,CYCS,UBE2I,SDHA,RPL23A,RPL17,ARL6IP1,TALDO1,PABPC1,EEF1D,KDELR1,LDHB,RPL35,TSTA3,RPS10,LDHA,JTB,RPL8,RPL38,TUFM,MCL1,SOX4,RAB1A,RPL27A,ODC1,TRIM28,PRDX1,CBX3,YIF1A,PTPRF,RPL37,KPNA4,PDCD6,DDOST,PSMD8,STAT1,UQCRH,GPI,UBE2C,PFKP,ZNF146 |
| 4.093e-06 | -12.41 | COPII-coated vesicle budding | biological process | GO:0090114 | 69 | 26 | 17256 | 2622 |
USO1,TRAPPC9,GORASP1,CUL3,MCFD2,RAB1A,PEF1,SEC16A,ANKRD28,CD59,SEC31A,SEC23IP,PDCD6,GOLGA2,NSF,TMED10,SAR1A,SEC24C,PPP6C,PPP6R3,TFG,LMAN1,PPP6R1,TMED2,CSNK1D,PREB |
| 4.093e-06 | -12.41 | RAD21 (RAD21 cohesin complex component) | protein interactions | 5885 | 261 | 71 | 17029 | 2761 |
PPP1R15B,EIF3D,ACTR3,OLA1,RPL11,RPL23A,ANKRD28,PCNA,PDS5B,TFG,CFL1,CDKN2AIP,CCT2,RFC3,TOR1AIP2,BRCA1,SMC2,MCM2,EIF3A,SEPT1,RPS27A,CHD3,RPS14,NSMCE2,CLU,PSMC1,CAPN1,USP13,KIF3B,UNK,EWSR1,RPS2,CHTF18,CCM2,NACA,DHX9,CTCF,NCAPG,RPA2,PSMD2,SMC3,RPL17,ARPC5,MSH2,CTPS1,MEA1,YBX1,UBE3C,RPL22L1,EEF1D,MSH6,SMC4,FOCAD,PRKDC,PSPC1,MIER1,TOP3A,RPL6,RPS10,API5,CCT8,DAPK3,RPA1,NAP1L1,SYNCRIP,SETD3,CDCA5,LRPPRC,ACAT1,DDB1,ANAPC4 |
| 4.101e-06 | -12.40 | GO_NUCLEAR_TRANSCRIBED_MRNA_CATABOLIC_PROCESS_NONSENSE_MEDIATED_DECAY | MSigDB lists | GO_NUCLEAR_TRANSCRIBED_MRNA_CATABOLIC_PROCESS_NONSENSE_MEDIATED_DECAY | 116 | 37 | 17377 | 2626 |
RPS15,RPS2,RPLP2,GSPT2,RBM8A,RPL15,PARN,RPL11,RPL23A,EIF4A3,RPL17,DCP1A,UPF2,RPL19,PABPC1,RPL29,RPL35,RPL8,RPL38,RPL6,RPS10,RNPS1,RPS24,RPL27A,RPS9,RPSA,RPL36,RPL37,PPP2CA,UPF1,RPL32,RPS27A,RPS14,RPLP1,SMG9,FAU,RPS26 |
| 4.115e-06 | -12.40 | fibrous_tissue_and_uncertain_origin | COSMIC cancer mutations | fibrous_tissue_and_uncertain_origin | 283 | 71 | 17385 | 2587 |
ANKRD27,NOP2,TSC2,NF1,SF3B1,RAC1,SAFB2,MEAF6,RNF103,CDKN2C,JAZF1,ETV6,RBM12B,TFG,ARID4A,DCTN1,ABCC5,ENPP4,SGCE,NRAS,ERMP1,NCK1,VHL,OGDH,EML4,DHX57,DHX15,DNAJC10,SCAP,AXIN1,HIPK2,ACTB,STK11,FUS,CLN3,H3F3A,TRAF5,SMAD4,EWSR1,TRIP12,TM9SF4,EPN1,KIF5B,RB1,FGFR3,ITGB8,PTEN,ATIC,PTPN11,MSH2,TIMELESS,SS18L1,CPSF4,FBL,STAT3,KRAS,GORASP2,KCNQ1,MEN1,PATL1,MAP2K2,DAPK3,GNAS,SEC31A,EPRS,TSC1,SGSH,ZC3H7B,PGAM1,HRAS,CDKN2A |
| 4.122e-06 | -12.40 | SMAD2 (SMAD family member 2) | protein interactions | 4087 | 280 | 75 | 17029 | 2761 |
TCF12,PTMS,ST13,TSC2,ANK3,DHX8,SMARCA4,IRF3,AP1B1,PAPOLA,UCHL5,PIN1,ZNHIT6,SRI,NUP153,STRAP,POU2AF1,BRCA1,ERBIN,SLC25A5,GFER,AFDN,SMAD2,CDC16,HSPA4,RBL1,GRIPAP1,RPS27A,PSMD8,RPS14,E2F4,AXIN1,HIPK2,ANP32E,ROCK1,DVL1,SMAD1,MAPK1,SMURF1,SMAD4,CSNK1D,PARD3,HDAC2,RHEBL1,CDC40,MEF2A,FOXO3,ARID1B,WWP2,WRNIP1,HUWE1,CITED2,CAMK2G,EIF3L,DCAF6,RHOA,KAT2A,ZMYND11,PSPC1,ANAPC2,RIT1,ARID1A,MAPK3,C22orf46,HGS,CDC27,MED15,PML,PSAP,SNRNP70,YY1,CDK2,TOB1,FAM83G,SNAPIN |
| 4.125e-06 | -12.40 | GSE37532_TREG_VS_TCONV_CD4_TCELL_FROM_VISCERAL_ADIPOSE_TISSUE_DN | MSigDB lists | GSE37532_TREG_VS_TCONV_CD4_TCELL_FROM_VISCERAL_ADIPOSE_TISSUE_DN | 157 | 46 | 17377 | 2626 |
DDX58,COMMD10,KARS,KDM4A,RRM1,NHLRC3,NCAPG,SYNRG,NUP205,CFLAR,GNS,ERH,PA2G4,MDM2,CDC42,IMPAD1,SSBP3,BDH1,SLC44A1,INTS12,MOB1A,STAT3,STRAP,ARL5A,MRPL32,TSHZ1,RFC3,PBK,POLR2D,ILF3,SLBP,EIF2A,LRRC1,ANLN,KIF11,PLEKHF2,BTBD1,ARF4,PSMC4,PRIM1,GOLGA7,CAPN7,QRSL1,LY75,NDE1,HDAC2 |
| 4.139e-06 | -12.40 | RUIZ_TNC_TARGETS_DN | MSigDB lists | RUIZ_TNC_TARGETS_DN | 134 | 41 | 17377 | 2626 |
MCM10,HJURP,FOXM1,TMEM97,KIF2C,ORC1,BLM,POLR3K,FANCI,DTL,RFWD3,OIP5,CCNA2,MCM5,POP7,EIF5,MYBL1,GINS1,PBK,RAD51AP1,DNAJC9,RRM2,CDC6,AURKB,MCM2,SHCBP1,ODC1,ASF1B,NMT2,RAD54B,ABHD5,PRIM1,PTPRF,ATAD2,CCDC86,BIRC5,H2AFX,E2F1,UBE2C,YWHAH,PFKP |
| 4.181e-06 | -12.39 | MODULE_105 | MSigDB lists | MODULE_105 | 195 | 54 | 17377 | 2626 |
TCF12,HSPH1,FOXM1,DAP,SRSF6,UBXN1,RRM1,MAN2B1,BLM,CCNB1,PSEN1,SLC20A1,BIRC2,CHKA,PCNA,GART,CCNA2,GOT2,MTA1,CRAT,LPIN2,RAB4A,PPP4R1,DNM2,MSH2,KNTC1,CITED2,GALC,MAPKAPK3,ERF,LRBA,MRPL12,MYBL2,MKI67,ILF3,RRM2,CCNF,SOX4,ARPC1A,HAGH,PRPSAP1,FADD,CHAF1A,RPA1,DDX17,MKNK1,KEAP1,POLR2J,BIRC5,FAM3C,ADAM9,PDXK,GCSH,PFKP |
| 4.220e-06 | -12.38 | nucleoside phosphate biosynthetic process | biological process | GO:1901293 | 228 | 61 | 17256 | 2622 |
GALK1,NADSYN1,KARS,COX5B,PPCS,SUCLG1,UCK2,RRM1,UCK1,SLC35B2,ADPGK,ATP5F1B,ATP5PF,HDDC2,FLAD1,ERH,GART,DUT,ATIC,ADCY9,CTPS1,PPCDC,UPRT,ATP6V0A2,SLC26A2,CYC1,RNLS,ADCY7,AMPD2,TGFB1,TK1,GUK1,CGAS,LDHA,NADK2,ADSL,RRM2,ATP6V0A1,DCTD,OGDH,PKM,ATP5MF,PRPSAP1,STOML2,ADSS,ATP5MC3,DCK,GUCY1B1,PRPS2,TBPL1,NAXE,IMPDH1,ACAT1,DHTKD1,GPI,ATP5F1A,NIPSNAP2,PARP10,PGAM1,MAPK1,PFKP |
| 4.226e-06 | -12.37 | positive regulation of cellular biosynthetic process | biological process | GO:0031328 | 1801 | 340 | 17256 | 2622 |
ZNF496,H2AFZ,CXXC1,HEXB,YTHDF3,CCNL2,EDRF1,PARK7,GLMP,CALM2,USF1,NOL11,DNM2,ECD,SENP1,CDC5L,KLF10,AATF,GABPA,AKT2,TOPORS,USP22,AURKB,RFC2,CBFB,ARF4,STOML2,DOT1L,MAP3K4,HHEX,MID1IP1,SMAD2,RPS27A,AXIN1,OGT,RNASEL,TFDP2,SMAD1,ARRB2,E2F2,NMD3,HDAC2,SVIP,DDX58,HIVEP3,HSPH1,CHTF18,PRKAA1,DHX9,EZH1,EIF2AK4,PSMD9,PARN,PSEN1,METTL3,CDC73,DDRGK1,TFAP4,FOXN2,MYDGF,PABPC1,NUP85,NSUN4,EIF5A,FOXK1,MTA2,MYBL2,BCLAF1,EXOSC9,ARID1A,ADRB2,ELK1,FXR1,KDM3A,MAP2K2,CCT8,XRCC5,SERTAD2,GOLGA2,ETS2,SETD3,RBMX,PIAS2,PPP3R1,CEBPG,YY1,MAP3K5,RNF14,CDK2,EGLN1,RHOG,KARS,TRERF1,IVNS1ABP,RPS6KA1,RAF1,EIF3D,MAGED1,RAC1,CREBL2,APP,CCNA2,SHC1,SP100,GMEB1,LPIN2,MRPS27,MAVS,RBM15,ATF2,RPRD1B,CDK12,CCT2,PSRC1,BRD4,RFC3,CDC123,KAT7,WBP2,POLR2D,CIRBP,E2F3,PFKFB3,EDF1,MEF2D,TAZ,SERP1,TRIM28,SUPT16H,DDX17,TAF2,VEZF1,SAFB,HIPK2,STAT1,TICAM1,ATF6,ATMIN,POU3F2,MECP2,TCF3,HABP4,ABHD14B,WDR5,BLM,ETS1,FOXO3,MAD2L2,WWP2,GTF2F1,CCNK,PRDM4,CARF,CITED2,CREB1,NCOA2,PPP3CA,KAT2A,NEK7,RFXANK,ILF3,ZP3,KLF6,PICALM,FADD,GPS2,PITX1,TFDP1,PML,DDX5,HMGB2,CD81,USF2,YWHAH,RORB,CCNC,ZBED3,ZNF76,IER2,HNRNPAB,THOC1,AGRN,AAMDC,NF1,KMT2E,GPBP1L1,FAM129A,SIRT2,MAPK14,CREM,TET3,PCNA,GLIS2,EIF4A3,ZNF639,ETV6,PIK3R2,MYBL1,ARID4A,CARM1,ELOF1,RYBP,SP3,DEAF1,NCK1,VHL,MRPL12,UBE2V1,LRP5,BRCA1,EAF2,SOX4,USP21,UBTF,PAF1,E2F4,ZNF268,CHEK2,DVL1,CLU,POT1,PSMC1,ZNF564,PPP1R12A,CHCHD2,CTCF,MEF2A,CDK13,PPP3CB,THRAP3,RLF,ASXL2,CRLF3,ARID1B,SUB1,RB1,MLX,NFATC3,MED10,SSBP3,ZNF746,CTR9,ICE2,RBM3,YBX1,MDFIC,MAML1,ERLIN1,ACSL3,LDB1,GBA,UTP15,RTF1,EIF2A,NFATC2IP,IRF5,CAND1,RXRB,PSMC4,TBPL1,NLRC5,NUP62,ZFP90,RUVBL2,SMARCD1,TCF12,ASH1L,FOXM1,SMARCA4,PLAGL2,IRF3,PCBP1,PAIP1,HNRNPA2B1,RRN3,NRF1,NVL,PIN1,TARDBP,F2R,DVL2,CHP1,MOSPD1,POU2AF1,TIMP2,POLR2G,NFATC2,RPS9,RBL1,SCAP,STAT6,ARNTL,SCARB1,NCOA1,AKNA,MAPK1,SMAD4,NAT14,SLC30A9,BCL2L12,DNAJC2,EYA1,CDT1,AGO2,DBF4,KLF13,PAWR,NKRF,HMGN3,PAGR1,PTPN2,FASTKD3,IRF4,BRD7,ARHGEF2,SS18L1,PTGES3,STAT3,TGFB1,ELOVL5,COA3,DCAF6,RHOA,HMGN1,HMGN5,PRKDC,PRMT2,MEN1,MAPK3,TFEB,ATAD2,TFE3,E2F1,KMT2B,PKD2,RBPJ,NR2F2,ZMIZ1,HRAS,IFI16 |
| 4.228e-06 | -12.37 | NOP53 (NOP53 ribosome biogenesis factor) | protein interactions | 29997 | 109 | 37 | 17029 | 2761 |
DDX58,RPS15,ZCCHC9,NOP2,YTHDC2,CTCF,CSNK2A1,EBNA1BP2,BRIX1,ZNF121,MDM2,PTEN,RBM34,RPF2,YBX1,DDX31,UPF2,UTP4,ZC3H3,FTSJ3,ZNF189,SRPK2,FYTTD1,FTL,ZNF512,GTPBP4,PSMA1,UTP3,CAND1,NSA2,DAP3,UPF1,NIP7,RRS1,CDKN2A,ZC3HAV1,CCDC137 |
| 4.243e-06 | -12.37 | WD_REPEATS_2 | prosite domains | PS50082 | 228 | 57 | 12060 | 1670 |
WSB2,CORO7,CDC40,COPA,TRAF7,RAE1,WDR13,POC1A,WDTC1,STRN4,WDR5,GNB2,WDR48,COPB2,DTL,WDR44,UTP18,FBXW2,TAF5L,CORO1A,STRAP,SEH1L,CSTF1,WDR41,PRPF19,MLST8,PREB,WDR1,DCAF8,WDR18,SMU1,UTP15,WDHD1,WDR82,WDR81,PPWD1,ARPC1A,EML4,GEMIN5,SEC31A,PLAA,BRWD1,SCAP,TBL3,CORO1C,WDR59,WDR4,DCAF11,WDR7,PRPF4,DMWD,RBBP4,WDR91,WDR62,BRWD3,DCAF5,AAAS |
| 4.259e-06 | -12.37 | HDAC11 (histone deacetylase 11) | protein interactions | 79885 | 143 | 45 | 17029 | 2761 |
HJURP,NOP2,XAB2,DNAJB2,CDT1,EBNA1BP2,ATG2B,THRAP3,SEC16A,WRNIP1,SF3B2,RB1,SMC3,ADD3,HUWE1,UTP18,RBM34,BDH1,AKAP8,ZNF326,NUP153,GEMIN4,RBM12B,UTP4,SCYL3,NUP85,PPP6R1,MSH6,SMC4,PPAN,CCT2,PRKDC,AMD1,DDX20,BCLAF1,DNAJA1,POLR2A,ZFR,MTMR3,ATAD2,MAPK6,PML,BAZ1B,PPP6R3,PDCD11 |
| 4.259e-06 | -12.37 | UBA1 (ubiquitin like modifier activating enzyme 1) | protein interactions | 7317 | 143 | 45 | 17029 | 2761 |
UBE2D3,UNK,KARS,HSPH1,UBE2E2,PDCD6IP,UBE2Z,AP1B1,BIRC2,CDC73,SAPCD2,NPLOC4,USP5,RAD23A,MCTS1,UBE2Q2,IARS,NVL,HUWE1,AHSA1,ATIC,RAD23B,AP1M1,CTPS1,MTPN,PABPC1,LARS,BIRC3,NSUN2,CUL3,EZR,KRAS,BRCA1,MAPK3,EPRS,HGS,QARS,AP1S1,DNPH1,FUS,USP11,CDK2,UBE2C,NMD3,DDB1 |
| 4.269e-06 | -12.36 | GSE5099_UNSTIM_VS_MCSF_TREATED_MONOCYTE_DAY7_UP | MSigDB lists | GSE5099_UNSTIM_VS_MCSF_TREATED_MONOCYTE_DAY7_UP | 176 | 50 | 17377 | 2626 |
UBE2D3,GCLM,NSMCE4A,H2AFZ,ZNF445,MUT,MRPL39,OLA1,ARGLU1,COX4I1,POMP,CCNL2,DAZAP2,EIF1B,AP3S1,RLF,RPL23A,STRBP,MED10,RPL17,RBM34,BANF1,EXOSC1,NSFL1C,NDUFB9,ALDH18A1,SRSF10,CDC5L,USP34,GINS1,PHF10,EIF3L,NASP,SNX2,GABPA,NEK7,PBK,APPL1,BTBD1,EIF3A,TWISTNB,SH3GLB1,ANKRD10,FNTA,TMEM168,ZHX1,TPP2,CTBS,NLRC5,ANAPC4 |
| 4.280e-06 | -12.36 | establishment of protein localization to membrane | biological process | GO:0090150 | 233 | 62 | 17256 | 2622 |
RPS15,RPS2,GOLPH3L,SYS1,RPLP2,RAB11B,ANK3,RPL15,RAB11A,WRB,ATG4A,SSR1,RPL23A,RPL11,MOAP1,RAB8A,RPL17,ATG3,ARL6IP1,RPL19,SRP72,ZDHHC18,GCC2,RPL29,SEC61B,RPL35,RPL6,RPL8,RPL38,RPS10,SSR2,RPS24,RAB3IP,ICMT,RPL27A,MACF1,RPS9,ZDHHC3,RPSA,OPTN,RPL36,RPL37,TRAM2,PEX5,GOLGA4,TIMM13,HSPA4,CHMP4A,RPL32,GOLGA7,SEC61A1,NSF,GRIPAP1,RPS27A,TIMM29,RPS14,RPLP1,EXOC4,ZDHHC7,CHMP4B,RPS26,PARD3 |
| 4.330e-06 | -12.35 | mitochondrial transport | biological process | GO:0006839 | 238 | 63 | 17256 | 2622 |
COX5B,TOMM20,MTX3,DYNLL1,SLC25A12,TIMM21,ABCB10,BCL2L1,ATP5F1B,SLC25A44,ATP5PF,SLC25A43,PSEN1,SLC25A37,SLC25A36,MOAP1,TIMM23,FBXO7,SLC25A51,MICU2,BCL2,CYC1,TP53BP2,ATF2,STAT3,MTX2,SLC25A1,TIMM50,BAK1,PPIF,TIMM8B,ATP5IF1,MRS2,HEBP2,SLC25A22,MTX1,RHOT1,TOMM40,ATP5MF,SLC25A5,RHOT2,MPC1,STOML2,MFN2,MID1IP1,TIMM13,HSPA4,ATP5MC3,TIMM29,TIMM17A,TFDP1,E2F1,PPP3R1,SLC25A19,YWHAZ,ATP5F1A,TFDP2,TMEM14A,PITRM1,YWHAH,SLC25A39,EYA2,SLC25A33 |
| 4.371e-06 | -12.34 | ATP6V0D1 (ATPase H+ transporting V0 subunit d1) | protein interactions | 9114 | 105 | 36 | 17029 | 2761 |
RPS2,NDUFS1,ATP5F1B,IKBIP,ATP6V1B2,SDHA,GNB2,NDUFS4,SSR1,RFWD3,RPA2,RPN1,NDUFV1,NDUFA2,ATP6V0A2,SNX25,STAU1,RAB7A,VDAC2,ATXN1,ATP6V0A1,VDAC1,SLC25A5,ERC1,EIF3A,RPA1,ATP1A1,ATP6V1D,MID1IP1,NSF,PSMD3,CHMP4B,ATP6V0C,UQCRH,ATP5F1A,SLC22A23 |
| 4.397e-06 | -12.33 | LARP7 (La ribonucleoprotein domain family member 7) | protein interactions | 51574 | 58 | 24 | 17029 | 2761 |
NOL12,RPP25,NIFK,RPS2,MTA2,RPL6,CSNK2A1,JMJD6,ORC1,TRIM28,APP,RPSA,CAND1,HUWE1,HNRNPR,VCPIP1,AFF1,FBL,SNRNP70,TERF1,ZC3H3,IFI16,LUC7L2,TERF2 |
| 4.397e-06 | -12.33 | SURF2 (surfeit 2) | protein interactions | 6835 | 58 | 24 | 17029 | 2761 |
RPRD1A,ZCCHC9,DHPS,RIOX2,AGFG1,BRIX1,APP,PABPC4,NPLOC4,RPL11,PRNP,MDM2,HSPBP1,PPME1,WDR4,KBTBD7,OGT,H2AFX,YBX1,RRS1,B4GALT3,PURA,FTSJ3,RPRD1B |
| 4.402e-06 | -12.33 | Nek2 (NIMA (never in mitosis gene a)-related expressed kinase 2) | protein interactions | 18005 | 37 | 18 | 17029 | 2761 |
PPP1R2,DEPDC1,FOXM1,DLGAP4,CDCA3,CDC23,PRPF18,KIFC1,MKNK1,CDC16,MTHFD2,CDC27,BBX,IARS2,LTN1,ANAPC7,ACAD8,PDF |
| 4.406e-06 | -12.33 | DNA-directed RNA polymerase complex | cellular component | GO:0000428 | 146 | 43 | 18223 | 2701 |
INTS2,POLA2,CTDP1,POLR2K,ZNF768,TAF6L,POLR3K,CDC73,GTF2F1,MED8,MED10,INTS7,INTS1,CTR9,INTS12,TAF5L,POLR1B,TCEA1,ZNRD1,GTF2H2,RPRD1B,ERCC1,POLR2I,RPRD1A,KAT2A,POLR2L,POLR2G,PRIM2,HELB,POLR2D,POLR3GL,RTF1,EDF1,TWISTNB,POLR2A,PRIM1,PAF1,TAF2,POLR2J,TBPL1,CRCP,TAF12,TAF6 |
| 4.414e-06 | -12.33 | GCM_TPR | MSigDB lists | GCM_TPR | 29 | 15 | 17377 | 2626 |
SP3,TRIM26,PCM1,IARS,COPA,DHPS,IDH3A,DHX9,MPV17,TRA2B,CTR9,PTGES3,MEN1,DDX39A,PCBP1 |
| 4.414e-06 | -12.33 | ZHAN_VARIABLE_EARLY_DIFFERENTIATION_GENES_DN | MSigDB lists | ZHAN_VARIABLE_EARLY_DIFFERENTIATION_GENES_DN | 29 | 15 | 17377 | 2626 |
NAP1L1,QARS,ATIC,SAFB,ATP13A3,SRI,RABIF,CNN2,PPP3CB,CCNB1,VDAC1,FXR1,FBL,GNAI2,MARK2 |
| 4.414e-06 | -12.33 | LY_AGING_PREMATURE_DN | MSigDB lists | LY_AGING_PREMATURE_DN | 29 | 15 | 17377 | 2626 |
NASP,FOXM1,SAFB,H2AFX,MYBL2,HMGB2,MCL1,KIF2C,CDC25B,PKMYT1,MCM2,CCNF,FBL,DDX39A,HMGN2 |
| 4.455e-06 | -12.32 | ONKEN_UVEAL_MELANOMA_DN | MSigDB lists | ONKEN_UVEAL_MELANOMA_DN | 500 | 113 | 17377 | 2626 |
UBL3,TOMM20,LYRM4,H2AFZ,ST13,COPA,RAF1,FAM129A,TMEM97,CREBL2,TGOLN2,DAZAP2,EIF1B,DUSP22,CMTM6,EPM2A,MBD4,RPL11,SEC11A,CSDE1,SYNM,ATG3,DPYSL2,RABGAP1L,RAB4A,ATP13A3,PARL,TIPARP,GPD1L,CTDSP2,CGGBP1,RYBP,RPL29,RHOBTB3,RAB7A,CIRBP,CHMP2B,MCM2,EIF3G,RPS9,SERP1,ERC1,LSG1,RPSA,ARF4,PEX5,DDOST,AGPAT2,SCAP,RPS27A,EIF2D,PRPF4,LTA4H,NMD3,ZMAT3,PDCD4,RMND5A,MAGEH1,MAPRE1,KLHL21,GORASP1,CUTA,TRAK1,TKT,LETMD1,ASAH1,RPL15,TOP2B,HAUS4,CCDC28A,FZD6,WWP2,SLC25A36,ADD3,PDCD10,PTEN,NDUFB4,LRRC8D,NAA50,FBL,ALDH9A1,NIPSNAP1,FDFT1,EIF3L,HEMK1,RHOA,GALC,CREG1,WDR1,ITM2A,LRRC1,ADRB2,FXR1,ZDHHC3,APPL1,NMT2,GNAS,SCARB2,NAP1L1,KPNA4,GOLGA4,RPL32,DUSP3,QARS,SNAP23,CAPN7,COX7A2L,FAM3C,BBX,SLC16A1,PREPL,CDK2,MZT2B |
| 4.455e-06 | -12.32 | GSE46468_LUNG_INNATE_LYMPHOID_CELL_VS_SPLEEN_CD4_TCELL_DN | MSigDB lists | GSE46468_LUNG_INNATE_LYMPHOID_CELL_VS_SPLEEN_CD4_TCELL_DN | 181 | 51 | 17377 | 2626 |
HSPH1,NUP188,CKLF,URB2,PPP1R15B,ACTR3,TRMT6,YTHDF3,TM9SF3,EBNA1BP2,AGFG1,EIF1B,PNO1,TET3,ZNF473,ATP2A2,IARS,ZNHIT6,BUD31,INTS12,TRA2B,DDX31,TTC4,RNF19A,MAP3K14,EIF5,STRAP,KLF10,TSPAN31,COQ10B,ILF3,POLR2D,UTP15,RCOR1,EXOSC9,PITPNB,VDAC1,MAK16,MAT2A,ADSS,DERL1,SLCO4A1,ATP1A1,KPNA1,TAB2,FAM3C,LMBR1,AP1S1,SMURF1,PDCD11,BYSL |
| 4.455e-06 | -12.32 | GSE45881_CXCR6HI_VS_CXCR1LO_COLONIC_LAMINA_PROPRIA_UP | MSigDB lists | GSE45881_CXCR6HI_VS_CXCR1LO_COLONIC_LAMINA_PROPRIA_UP | 181 | 51 | 17377 | 2626 |
PARP12,TRIP12,DCAF15,IVNS1ABP,TMEM41B,MECP2,YTHDC2,AP3M2,PCSK7,KLC1,THRAP3,RCOR3,RAPGEF6,FAM8A1,PDXDC1,NUP205,HERC3,WDR44,HDAC7,MTA1,IL6ST,PPME1,KIFAP3,TARDBP,CLDND1,LMAN1,CDK12,NCOA2,SMC4,PHF20L1,DCAF8,ANAPC2,PTTG1IP,GFER,EML4,POLR2A,EIF3A,ADSS,MAP3K4,TAF2,KPNA1,RBM25,GOLGA7,HNRNPH3,GOLGA8A,TPP2,PROSER1,ARNTL,APPL2,CENPT,FUBP1 |
| 4.455e-06 | -12.32 | GSE17721_CTRL_VS_POLYIC_24H_BMDC_UP | MSigDB lists | GSE17721_CTRL_VS_POLYIC_24H_BMDC_UP | 181 | 51 | 17377 | 2626 |
NDUFV2,TOMM20,LZTR1,ANXA6,CASP6,MEF2A,HAUS4,C19orf48,PIP4K2A,PARK7,PNO1,HEATR5B,EBP,SMC3,AHCTF1,CCNA2,TNFAIP8,RCSD1,AKR1B1,BCAP29,MRPL48,TALDO1,ABI1,OGG1,MYO5A,TSHZ1,ARHGAP17,ELOVL5,ERMP1,PPP1R18,NEK7,RAB7A,RPL6,ARHGDIB,TMEM147,SOX4,ANLN,PRKRA,ARPC1A,MATR3,CLNS1A,NUCB1,ACLY,RPLP1,QRSL1,CTSA,CCNB2,CD81,MYL12B,AAAS,FAF1 |
| 4.455e-06 | -12.32 | GSE40273_EOS_KO_VS_WT_TREG_UP | MSigDB lists | GSE40273_EOS_KO_VS_WT_TREG_UP | 181 | 51 | 17377 | 2626 |
UBL3,PPIB,PRKCSH,GPR89A,MOGS,B4GALT1,ZFYVE21,SLC35B1,FOXO3,NPLOC4,SSR1,SLC31A1,RPN1,NUS1,MLX,NEK6,RRBP1,TPST1,LMAN1,PDIA6,SGCB,LRRC59,IFT46,TMX1,KDELR1,SRP72,FTL,USO1,ATG9A,TMEM39A,SELPLG,ZMYND11,SCFD2,ATXN1,EMP3,DTWD1,NUCB1,TRAM2,ALDH3B1,GALNT2,TMED10,CERS6,ERGIC3,PML,ATF6,PSAP,PLOD3,PDLIM5,CD81,GPR89B,STARD3NL |
| 4.455e-06 | -12.32 | GSE27786_LSK_VS_NKCELL_DN | MSigDB lists | GSE27786_LSK_VS_NKCELL_DN | 181 | 51 | 17377 | 2626 |
DDX58,UBL3,PPIB,CHMP2A,HECA,SYS1,DHPS,HEXB,DLGAP4,SLC35B1,CDIPT,TWF2,BECN1,ITGB5,TMEM161B,MLX,RINL,LRRC8D,MBD2,RRBP1,AKR1B1,GLTP,ABCD1,HTRA2,ABCC5,TRIM8,MKLN1,FOXK1,C16orf72,KIAA0930,CRNKL1,PLEKHM3,RIT1,EDF1,LY6E,PDE3B,NECAP2,DERL1,WAS,MTHFD2,RBM47,CLK3,HPS5,ACLY,DNAJC17,NLRC5,CHMP4B,TAF12,DCAF5,PDCD4,ESYT2 |
| 4.474e-06 | -12.32 | GO_NEGATIVE_REGULATION_OF_TRANSFERASE_ACTIVITY | MSigDB lists | GO_NEGATIVE_REGULATION_OF_TRANSFERASE_ACTIVITY | 341 | 83 | 17377 | 2626 |
FGFR1OP,TSC2,NF1,CCNB1,DUSP22,LYN,PARK7,CDKN2C,PSMD1,PSMA6,SOCS6,CDKN1B,ANAPC7,PLK1,NCK1,GMFB,CUL3,PSMB7,LRP5,DNAJA1,CDC23,PRPSAP1,PSMB9,SOCS7,PPP2CA,HHEX,CDC16,PPP2R5A,RPS27A,PSMD8,LIMK1,STK38,CORO1C,PSMD3,GADD45B,SOCS4,DVL1,PSMC1,POT1,PDCD4,GMFG,CIB1,AKT1S1,RGS2,PSMD9,PSEN1,MAD2L2,FBXO5,PTPN2,TFAP4,RB1,PSMD2,PTEN,FBXO7,H2AFY,PIK3IP1,MVP,SOCS5,PDPK1,TNFAIP3,PRKAR1B,GBA,PSMA1,ANAPC2,MEN1,PSMB3,PSMC4,SH3BP5,MBIP,CDC27,PRDX3,GPS2,DUSP3,CSK,PML,NUP62,NR2F2,CDK2,UBE2C,HIPK3,TERF1,CDKN2A,ANAPC4 |
| 4.486e-06 | -12.31 | Rmdn3 (regulator of microtubule dynamics 3) | protein interactions | 67809 | 77 | 29 | 17029 | 2761 |
NDUFV2,IMMT,TMUB1,NDUFS1,PHB2,ERLIN1,ATP2C1,VDAC2,FLOT1,ATP6V0A1,NDUFA7,ATP6V1B2,VDAC1,TXNL4A,CHCHD6,FAM8A1,XPR1,STOML2,CCDC127,CHCHD3,GNAS,DERL1,NDUFV1,NDUFA2,NDUFB4,PLGRKT,SARAF,ATP6V0D1,ATP6V1G1 |
| 4.486e-06 | -12.31 | SRSF10 (serine and arginine rich splicing factor 10) | protein interactions | 10772 | 77 | 29 | 17029 | 2761 |
STAU1,MZT1,PRKDC,SUZ12,ZMYND11,SRSF6,RPL6,SMU1,SREK1,CSNK2A1,USP39,LUC7L,TUBGCP2,DHX15,RPSA,SRSF1,CAND1,EPRS,EIF4A3,CLK3,SRSF4,PTPN11,MSH2,TRA2B,FUS,TCOF1,SNRNP70,NKAPD1,LUC7L2 |
| 4.493e-06 | -12.31 | FASN (fatty acid synthase) | protein interactions | 2194 | 101 | 35 | 17029 | 2761 |
COX15,CYLD,EWSR1,HAUS4,IRF3,SDHA,LMNA,SHC1,EIF4A3,PTEN,HUWE1,AHSA1,ZNF746,PTPN11,CRY2,PHKG2,CARM1,ABCC1,CDC5L,STAU1,VHL,CUL3,USP22,BRCA1,MCM2,KIF11,PEF1,ISG15,MAPK3,HSPBP1,IMPDH1,FUS,SMURF1,ARRB2,CDK2 |
| 4.534e-06 | -12.30 | microtubule | cellular component | GO:0005874 | 406 | 94 | 18223 | 2701 |
ZNF207,SKA3,CYLD,DYNLL1,TPX2,KIF2C,SIRT2,MAP1LC3B,STMN1,DST,KIFC1,CDK5,CALM2,ZNF804A,NEK6,ABRAXAS2,MTA1,KIF14,DPYSL2,DNM2,KIF22,KCNAB2,DNAL4,DCTN1,PLK1,CCT2,PSRC1,MAPRE2,SEPT9,PBXIP1,KIF15,CUL3,TUBGCP5,NUSAP1,AURKB,SERP1,EML4,EIF3A,KRIT1,KIF2A,CDC16,MID1IP1,KIF18B,MAP4,DVL1,REEP4,CSNK1D,TUBB,DYNC1LI2,CEP170B,HSPH1,KIF3B,MAPRE1,KLHL21,DCTN2,CDK2AP2,KLC1,KIF23,HAUS4,RACGAP1,RAB11A,HAUS2,TUBGCP2,NEIL2,SPAG5,JAKMIP1,KIF5B,CENPJ,KIF13B,PRC1,ARHGEF2,GTSE1,KIFAP3,KNTC1,MYO5A,NUDC,ASPM,NEK7,CAMSAP1,PARP4,KIF11,MACF1,CCT8,MAP2K2,HAUS8,KIF18A,CDC27,GOLGA2,BIRC5,TTLL4,ODF2,LRPPRC,NDE1,CFAP20 |
| 4.579e-06 | -12.29 | regulation of nuclear division | biological process | GO:0051783 | 185 | 52 | 17256 | 2622 |
ZNF207,CHMP2A,PDCD6IP,PHB2,CDT1,CENPF,PTTG1,CDK13,SIRT2,CCNB1,BECN1,MAD2L2,FBXO5,PDXP,RB1,SMC3,NEK6,PIN1,MSH2,H2AFY,CDKN1B,KNTC1,TACC3,PLK1,TGFB1,PPP1R9B,CUL3,MKI67,CDC6,NUSAP1,LRP5,PKMYT1,ANLN,CDC23,CHMP2B,KIF11,BORA,DAPK3,HSPA1B,CDC16,CDC27,NSMCE2,CDCA5,NUP62,CHMP4B,XRCC3,GEN1,SLF1,UBE2C,ESPL1,SLF2,ANAPC4 |
| 4.588e-06 | -12.29 | WDR46 (WD repeat domain 46) | protein interactions | 9277 | 97 | 34 | 17029 | 2761 |
NOP2,RRP15,YTHDC2,CERK,CDK13,EBNA1BP2,BRIX1,TTF1,DDX56,RBM34,DDX31,ZNF770,FTSJ3,HP1BP3,SRP72,STAU1,DDX24,ZNF512,GTPBP4,UTP3,BUD13,PRKRA,GAR1,MARK2,NSA2,ZNF317,ZNF777,UPF1,RPL32,RRS1,PURA,IFI16,ZC3HAV1,CCDC137 |
| 4.595e-06 | -12.29 | regulation of DNA metabolic process | biological process | GO:0051052 | 381 | 91 | 17256 | 2622 |
USP7,THOC1,MPHOSPH8,FOXM1,RAC1,TERF2IP,HNRNPA2B1,PCNA,BABAM2,CYREN,NVL,PARPBP,DNMT1,SPIDR,OGG1,RNF169,CCT2,ERCC1,EXOSC6,RFC3,RAD51AP1,MRNIP,CDC6,UBE2V1,AURKB,BRCA1,KDM1B,RFC2,MBD3,TRIM28,STOML2,MAP3K4,PPP2CA,STAT6,H2AFX,UHRF2,KPNA2,CHEK2,ARRB2,SLF1,MAPK1,POT1,EYA2,POLQ,DNAJC2,TRIP12,EYA1,MECP2,CHTF18,CDT1,BABAM1,DHX9,DBF4,BLM,RLF,PARN,TTF1,TFRC,WRNIP1,RPA2,SMC3,TIGAR,MBD2,MSH2,NABP2,AXIN2,TIMELESS,PTGES3,MSH6,TERF2,TGFB1,NEK7,HELB,WDR18,GTPBP4,PARP4,MEN1,CCT8,MAPK3,XRCC5,KPNA1,UPF1,KLHL15,PARG,PML,CEBPG,ZNF830,CDK2,HRAS,TERF1,SLF2 |
| 4.602e-06 | -12.29 | RAD18 (RAD18, E3 ubiquitin protein ligase) | protein interactions | 56852 | 81 | 30 | 17029 | 2761 |
USP7,RPS2,TRIM8,POLK,SHPRH,DBF4,PCGF6,CERK,SMC6,BRCA1,UBE2I,RFC2,PIP4K2A,FANCI,ATPAF1,USP5,CREM,WRNIP1,DTL,PCNA,RAD18,SIVA1,TULP3,TNPO3,ARRB2,ATF2,SLF1,SLF2,UBE2M,CDC5L |
| 4.617e-06 | -12.29 | ER to Golgi Anterograde Transport | REACTOME pathways | R-HSA-199977 | 133 | 43 | 10287 | 1696 |
TMED7,COPA,GORASP1,DYNLL1,COPE,DCTN2,ANK3,TMED3,ARF1,SEC16A,COPG2,COPB2,ANKRD28,CD59,NAPG,SEC24C,ARF5,PPP6C,TFG,LMAN1,PPP6R1,TMED2,KDELR1,PREB,DCTN1,SPTAN1,USO1,TMEM115,TRAPPC9,COG1,MCFD2,RAB1A,GOSR1,ARF4,SEC31A,SEC23IP,GOLGA2,NSF,TMED10,MIA2,PPP6R3,CSNK1D,DYNC1LI2 |
| 4.629e-06 | -12.28 | GSE5589_LPS_VS_LPS_AND_IL6_STIM_IL10_KO_MACROPHAGE_45MIN_DN | MSigDB lists | GSE5589_LPS_VS_LPS_AND_IL6_STIM_IL10_KO_MACROPHAGE_45MIN_DN | 186 | 52 | 17377 | 2626 |
NDUFS1,COPA,NQO1,GNPNAT1,THOC1,MRPS2,URB2,B4GALT5,MRI1,TKT,UBE2Z,ARGLU1,ARF1,EXT2,UBLCP1,USP5,CRKL,CCNK,ZBTB45,ATP6V0B,SLC1A4,NEK6,UTP18,PELO,PHTF1,EI24,NUP153,ANAPC7,POLR1B,ERI3,ZNF770,ATP6V0D1,UBE2M,TMED2,HP1BP3,RPAP3,CPNE1,SRP72,LARS,EIF3L,ABCF2,PCGF6,DDX20,C1orf122,AKAP1,MID1IP1,SLC38A7,LRPPRC,PITPNA,ASNA1,PDCD11,DYNC1LI2 |
| 4.629e-06 | -12.28 | GSE5589_LPS_AND_IL10_VS_LPS_AND_IL6_STIM_MACROPHAGE_45MIN_DN | MSigDB lists | GSE5589_LPS_AND_IL10_VS_LPS_AND_IL6_STIM_MACROPHAGE_45MIN_DN | 186 | 52 | 17377 | 2626 |
MIF,HSPH1,MAX,GPR132,MRPL42,KRBA1,ACTR3,CDCA8,HMGN3,NANS,BLM,FBXO5,LYAR,PDCD10,MED8,GOT2,ATG3,UCHL5,AHSA1,MBD2,BANF1,ETV6,ALDH18A1,NOL12,BAK1,TRAFD1,SEC61B,FAM49B,HARS,PGS1,DENND1B,PSMA1,CAPZA2,NUTF2,IL12RB1,AZI2,ANLN,LUC7L,MAK16,EIF3G,HSPA1B,DAP3,CDCA4,NFIL3,FAM3C,CENPT,RGL1,TAF12,TCOF1,CCNB2,CBX4,NUDT3 |
| 4.629e-06 | -12.28 | GSE32986_UNSTIM_VS_CURDLAN_HIGHDOSE_STIM_DC_UP | MSigDB lists | GSE32986_UNSTIM_VS_CURDLAN_HIGHDOSE_STIM_DC_UP | 186 | 52 | 17377 | 2626 |
POLA2,GALK1,CYTIP,POLR2K,NUF2,KIF2C,BCL2L1,EIF2AK4,XPO7,QSOX2,NPLOC4,EBP,RAD23A,ASPHD2,RFWD3,PA2G4,RRBP1,TXLNA,AP1M1,AP2B1,RNASEH2A,CYC1,ORC3,CPSF4,STAT3,MSH6,METTL5,POLR2D,TBRG4,SMC2,EAF2,METTL22,CCNF,EIF4H,CBFB,RFC2,SMAP2,RAD54B,MAGED2,MTHFD2,RAD18,HNRNPH3,ODF2,NFIL3,DHTKD1,CHEK2,PPP5C,REEP4,SASS6,COIL,AAAS,RHEBL1 |
| 4.629e-06 | -12.28 | GSE33425_CD8_ALPHAALPHA_VS_ALPHABETA_CD161_HIGH_TCELL_DN | MSigDB lists | GSE33425_CD8_ALPHAALPHA_VS_ALPHABETA_CD161_HIGH_TCELL_DN | 186 | 52 | 17377 | 2626 |
SLC12A7,GALK1,GCLM,PKP4,PTTG1,UCK2,KIF23,POMP,ARF1,BLM,AP3S1,STMN1,EBP,FAM192A,RAB8A,DAD1,PRC1,BCL2,DNMT1,IMPA2,SMC4,SEPT9,ASPM,SELPLG,EMB,POLR2D,GMFB,MKI67,FRAT2,CDC6,RAB3IP,MCM2,ANLN,PSMB9,PSMB3,ASF1B,RPA1,MYO1F,PRIM1,GEMIN5,GALNT2,SURF4,BIRC5,VPS26B,RPS14,CDCA5,DBI,H2AFX,KLHDC4,SASS6,PFKP,SSRP1 |
| 4.629e-06 | -12.28 | GSE11057_NAIVE_VS_CENT_MEMORY_CD4_TCELL_DN | MSigDB lists | GSE11057_NAIVE_VS_CENT_MEMORY_CD4_TCELL_DN | 186 | 52 | 17377 | 2626 |
UBL3,SMAP1,CAST,FAM129A,SRGN,C16orf87,PTTG1,CBLL1,SMC6,REEP5,SPPL2A,TERF2IP,ATP2A2,KLHL5,RABGAP1L,CLDND1,TAGLN2,RNF135,MYBL1,MYO5A,ABCC1,SAP30,ELOVL5,DENND1B,PARP4,EZR,ATXN1,EIF2AK1,OGDH,VDAC1,PICALM,ZDHHC3,SH3GLB1,MYO1F,FAS,OSBPL11,AHNAK,SURF4,GOLGA7,PPM1G,ARNTL,ITGB1,SIAH2,CTSA,PIEZO1,GALNT10,MAP3K5,EHD4,YWHAH,TSPAN5,PFKP,IFI16 |
| 4.633e-06 | -12.28 | GO_REGULATION_OF_RESPONSE_TO_EXTRACELLULAR_STIMULUS | MSigDB lists | GO_REGULATION_OF_RESPONSE_TO_EXTRACELLULAR_STIMULUS | 167 | 48 | 17377 | 2626 |
TBC1D12,FEZ2,SCOC,PHF23,ZDHHC8,NENF,UBQLN2,ATP6V1B2,MAP1LC3B,BECN1,PIP4K2A,PARK7,EPM2A,CDK5,ATP6V0B,RALB,TBC1D14,PARL,ATP6V0A2,PIKFYVE,LRSAM1,ATP6V0D1,HTRA2,RNF5,ATP6V1G1,UBQLN4,KAT2A,RAB7A,GBA,PIP4K2C,ATP6V0A1,ADRB2,VDAC1,SH3GLB1,USP36,MAPK3,MTMR3,TSC1,CHMP4A,ATP6V1D,VPS26B,EXOC4,ATP6V0C,CHMP4B,CLN3,ATP6V1C1,ATP6V0E1,CAPN1 |
| 4.633e-06 | -12.28 | GSE6269_HEALTHY_VS_STAPH_PNEUMO_INF_PBMC_UP | MSigDB lists | GSE6269_HEALTHY_VS_STAPH_PNEUMO_INF_PBMC_UP | 167 | 48 | 17377 | 2626 |
MUM1,TMEM97,ACAP1,STARD7,BTN3A1,CHKB,EZH1,MXD4,RBM4,EPM2A,EXOSC7,GSDMB,AHSA1,SEC24C,PIGG,TNPO2,TTC4,GEMIN4,CPSF4,NUP85,ILKAP,HTRA2,NASP,POLR2G,PBXIP1,ZMYND11,SUGP2,ADSL,DCTD,NFATC2IP,DIDO1,ESYT1,SLC25A5,LUC7L,PSMB9,RAD51C,NEK1,UPF1,JAK1,ACYP1,SAFB,GOLGA8A,PPM1G,WDR59,GLG1,USP11,LONP2,CSNK1D |
| 4.633e-06 | -12.28 | GO_REGULATION_OF_RESPONSE_TO_NUTRIENT_LEVELS | MSigDB lists | GO_REGULATION_OF_RESPONSE_TO_NUTRIENT_LEVELS | 167 | 48 | 17377 | 2626 |
TBC1D12,FEZ2,SCOC,PHF23,ZDHHC8,NENF,UBQLN2,ATP6V1B2,BECN1,MAP1LC3B,PIP4K2A,PARK7,EPM2A,CDK5,ATP6V0B,RALB,TBC1D14,PARL,ATP6V0A2,PIKFYVE,LRSAM1,ATP6V0D1,HTRA2,RNF5,ATP6V1G1,UBQLN4,KAT2A,RAB7A,PIP4K2C,GBA,ATP6V0A1,ADRB2,VDAC1,SH3GLB1,USP36,MAPK3,MTMR3,TSC1,ATP6V1D,CHMP4A,VPS26B,EXOC4,CHMP4B,ATP6V0C,ATP6V1C1,CLN3,ATP6V0E1,CAPN1 |
| 4.653e-06 | -12.28 | CAPZA1 (capping actin protein of muscle Z-line subunit alpha 1) | protein interactions | 829 | 93 | 33 | 17029 | 2761 |
MAPRE1,CYLD,KDM4A,SF3B1,DCTN2,MYH9,TWF2,RPA2,PSMA6,EIF4A3,HUWE1,UCHL5,RCSD1,STRAP,DCTN1,CDC5L,ARHGAP17,CUL3,PSMG1,PSMA1,CAPZA2,BRCA1,MPG,MCM2,ANLN,MCFD2,MARK2,PSMB3,RPA1,MYO18A,ACTB,SMURF1,ARRB2 |
| 4.653e-06 | -12.28 | PRDX6 (peroxiredoxin 6) | protein interactions | 9588 | 93 | 33 | 17029 | 2761 |
COX15,CUL1,NIT2,SPR,PARK7,TERF2IP,PCNA,HUWE1,UCHL5,AHSA1,AKR1B1,SUCLG2,GPX4,STAU1,RHOA,WDR1,GLO1,RANGAP1,VDAC1,PKM,PRDX1,ISG15,SDHB,HINT1,TMED10,PRDX5,H2AFX,MDH1,GPI,PITRM1,MAPK1,CDK2,TERF1 |
| 4.677e-06 | -12.27 | CHEK2 (checkpoint kinase 2) | protein interactions | 11200 | 122 | 40 | 17029 | 2761 |
FOXM1,DBF4,CUL1,NSD3,BLM,STMN1,APP,CDC73,RB1,MDM2,MSH2,STRAP,ILKAP,SRPK2,PLK1,PLK3,HMGN1,BRD4,FOXK1,AATF,POLR2L,PRKDC,VHL,RPS10,CDC6,BRCA1,PRMT2,TRIM28,DAPK3,MAPK3,GNAS,PPP2CA,PPP2R5A,E2F1,SIAH2,PML,KPNA2,CHEK2,MAPK1,ATMIN |
| 4.693e-06 | -12.27 | GO_NUCLEAR_ENVELOPE_REASSEMBLY | MSigDB lists | GO_NUCLEAR_ENVELOPE_REASSEMBLY | 17 | 11 | 17377 | 2626 |
ANKLE2,PPP2CA,UBXN2A,CHMP2A,UBXN2B,BANF1,NSFL1C,CHMP4B,REEP4,CHMP7,LMNA |
| 4.747e-06 | -12.26 | NS1 Mediated Effects on Host Pathways | REACTOME pathways | R-HSA-168276 | 40 | 19 | 10287 | 1696 |
NDC1,NUP188,RAE1,NUP54,NUP155,ISG15,NUP205,KPNA1,NUP210,KPNA4,NUP107,NUP62,KPNA2,NUP153,CPSF4,NUP58,NUP85,SEH1L,AAAS |
| 4.751e-06 | -12.26 | cell cycle G2/M phase transition | biological process | GO:0044839 | 134 | 41 | 17256 | 2622 |
FGFR1OP,MAPRE1,PPP1R12A,FOXM1,DYNLL1,DCTN2,ENSA,CUL1,HAUS4,CCNB1,PRKACA,HAUS2,RAB8A,CCNA2,CCP110,CENPJ,PPME1,AKAP8,DNM2,FBXL7,CEP63,CDC25B,DCTN1,PLK3,PLK1,PKMYT1,BORA,OPTN,MASTL,HAUS8,TAF2,PCM1,RPS27A,ODF2,SSNA1,CHEK2,NDE1,CCNB2,CDK2,TUBB,CSNK1D |
| 4.766e-06 | -12.25 | cell cycle G1/S phase transition | biological process | GO:0044843 | 125 | 39 | 17256 | 2622 |
POLA2,MAX,MCM10,GPR132,CDT1,DBF4,CUL1,ORC1,CRLF3,FBXO5,CDKN2C,RPA2,RB1,CCNA2,PCNA,MCM5,PPP6C,CDKN1B,ORC3,CAMK2G,PLK3,PPP3CA,BRD4,PRIM2,NASP,CUL3,RRM2,CDC6,MCM2,PRIM1,RPA1,POLE,E2F4,TFDP1,E2F1,ITGB1,TFDP2,CDK2,CDKN2A |
| 4.788e-06 | -12.25 | GSE22443_NAIVE_VS_ACT_AND_IL12_TREATED_CD8_TCELL_UP | MSigDB lists | GSE22443_NAIVE_VS_ACT_AND_IL12_TREATED_CD8_TCELL_UP | 191 | 53 | 17377 | 2626 |
CCDC93,TRIM41,PHF23,MRPL39,PHRF1,TCF3,TMEM97,CERK,LAGE3,EPN1,SIRT2,PPP3CB,SND1,EIF2AK4,XPO7,BZW2,PIP4K2A,TTF1,GNS,SMC3,RRBP1,MECR,AP1M1,TNPO2,UPF2,RNF26,DNMT1,CTDSP2,IMPA2,ACP2,GABPA,IDH3A,ABCF2,EIF2AK1,AURKB,SMAP2,ASF1B,TFEB,GNA12,PLD3,MKNK1,PFDN5,HINT1,CORO1C,LRPPRC,E2F1,RGL1,PDXK,FAU,PLOD3,USF2,TSEN15,SMARCD1 |
| 4.788e-06 | -12.25 | GSE17721_LPS_VS_PAM3CSK4_6H_BMDC_DN | MSigDB lists | GSE17721_LPS_VS_PAM3CSK4_6H_BMDC_DN | 191 | 53 | 17377 | 2626 |
BCCIP,HSPH1,UBE2E2,TP53RK,DNAJC5,NOP2,DYNLL1,WDR13,HNRNPUL2,CUTA,TWF2,PNO1,FLAD1,RRN3,ATP2A2,EFTUD2,ZNF326,RPF2,YBX1,AHCYL1,TMEM14C,KCNAB2,SLC39A9,FTL,SEC61B,POLR2I,RNASEH2C,FOPNL,HELB,RDH10,BOLA1,ARHGDIB,DDX39A,MRPS14,FANCE,MBD3,POLR2A,CLNS1A,MFN2,NECAP2,UTP20,TMEM184C,SEC31A,HSPA4,FNTA,DHX16,CORO1C,CDCA5,MPV17,SLC25A19,KPNA2,CTSA,ZNF830 |
| 4.788e-06 | -12.25 | GSE15930_STIM_VS_STIM_AND_TRICHOSTATINA_48H_CD8_T_CELL_UP | MSigDB lists | GSE15930_STIM_VS_STIM_AND_TRICHOSTATINA_48H_CD8_T_CELL_UP | 191 | 53 | 17377 | 2626 |
CYTIP,CMAS,CDS2,GMFG,ADD1,CASP6,GNPDA1,CAST,DAP,GADD45G,FLOT1,SIRT2,ARF1,OAT,TWF2,XPR1,PRNP,ANKRD28,CSDE1,IL6ST,FAM89B,ATP6V0A2,KIFAP3,AHCY,TAGLN2,MRPL48,S100A6,PTPRK,AKT2,EMB,LDHA,ARHGDIB,ADRB2,CYB5A,BTBD1,MYO1F,DDX17,NECAP2,PLD3,AHNAK,CDCA7L,OAZ2,ACLY,H2AFX,PQBP1,ST3GAL2,GPI,RBPJ,TMEM159,PGAM1,ZMAT3,SSRP1,S100PBP |
| 4.802e-06 | -12.25 | HSPA9 (heat shock protein family A (Hsp70) member 9) | protein interactions | 3313 | 220 | 62 | 17029 | 2761 |
UNK,HSPH1,CYLD,SUMO2,TKT,CUL1,PPP3CB,DNAJB1,STMN1,SDHA,POFUT1,HAUS2,ABHD14A,BZW2,APP,TUBGCP2,CDC73,CPNE3,C2orf68,UBXN2A,DNAJC8,SHC1,TNFAIP8,EIF4A3,ATG3,MCM5,DUT,GRSF1,NDUFS8,MAVS,EIF5,CFL1,LDHB,STAU1,RAB7A,LDHA,CUL3,LSM8,DNAJC9,KRAS,NFATC2,AURKB,BRCA1,DNAJA1,ADRB2,VDAC1,MCM2,CAND1,HSPBP1,AHNAK,PDCD6,HSPA4,TBPL1,DNAJC17,H2AFX,SLAIN1,FUS,COPS6,CDK2,SMURF1,CAPN1,CDKN2A |
| 4.830e-06 | -12.24 | V$SP1_Q6 | MSigDB lists | V$SP1_Q6 | 235 | 62 | 17377 | 2626 |
POU3F2,RHOG,CDC40,UGP2,PHF23,GGA1,DYNLL1,ZFP91,KLF13,MXD4,DCUN1D4,STMN1,CHKA,PTPN2,APLP2,KDM2A,ATP2A2,SNX18,UTP18,ARHGEF1,CNPY4,TIMELESS,ANP32A,CTR9,GLTP,UPF2,CREB1,SMARCE1,CAMK2G,CGGBP1,CDC37,RBM15B,ZNF524,POLR2I,KAT2A,SNX2,AKT2,DRAP1,LYRM1,LDB1,SLBP,RTF1,WDR81,CADM1,PRKRA,ELK1,ERC1,TRIM28,RAB2B,SH3BP5,ZNF282,FNTA,CORO1C,OAZ2,PITPNA,TAF6,ACSF2,CSNK1D,DDB1,SMARCD1,SNAPIN,PTOV1 |
| 4.837e-06 | -12.24 | PSMD2 (proteasome 26S subunit, non-ATPase 2) | protein interactions | 5708 | 179 | 53 | 17029 | 2761 |
CYLD,POMP,PSMD9,SDHA,CDC73,HLA-A,UBLCP1,SRXN1,RAD23A,PRNP,PTPN2,HERC3,PSMD2,MDM2,PSMD1,PSMA6,NEK6,HUWE1,UCHL5,AHSA1,ZNF746,UBA5,RAD23B,NSFL1C,CRY2,ECD,UBE3C,ABCC1,CDC5L,TXNL1,CCT2,STAU1,UBQLN4,PSMA8,IDH3A,CUL3,PSMB7,PSMA1,BRCA1,ADRB2,SYVN1,MCM2,PSMB9,PSMB3,PSMC4,DERL1,EPRS,SYNCRIP,PSMD8,PSMD3,CDK2,SMURF1,PSMC1 |
| 4.842e-06 | -12.24 | nucleotide biosynthetic process | biological process | GO:0009165 | 224 | 60 | 17256 | 2622 |
GALK1,NADSYN1,KARS,COX5B,PPCS,UCK2,RRM1,UCK1,SLC35B2,ADPGK,ATP5F1B,ATP5PF,HDDC2,FLAD1,ERH,GART,DUT,ATIC,ADCY9,CTPS1,PPCDC,UPRT,ATP6V0A2,SLC26A2,CYC1,RNLS,ADCY7,AMPD2,TGFB1,TK1,GUK1,CGAS,LDHA,NADK2,ADSL,RRM2,ATP6V0A1,DCTD,OGDH,PKM,ATP5MF,PRPSAP1,STOML2,ADSS,ATP5MC3,DCK,GUCY1B1,PRPS2,TBPL1,NAXE,IMPDH1,ACAT1,DHTKD1,GPI,ATP5F1A,NIPSNAP2,PARP10,MAPK1,PGAM1,PFKP |
| 4.859e-06 | -12.23 | UBE2D2 (ubiquitin conjugating enzyme E2 D2) | protein interactions | 7322 | 234 | 65 | 17029 | 2761 |
TRIM41,TXN,LUZP1,TRAF7,RAF1,TRIM11,XIAP,CCNB1,UBE2I,KCMF1,BIRC2,RNF103,ARL6IP6,MDM2,SIAH1,SOCS6,FBXW2,CDKN1B,TTC3,AHCYL1,RNF26,RLIM,TRIM8,BIRC3,RBX1,VHL,RNF25,CUL3,LNX2,TOPORS,UBE2V1,BRCA1,MCM2,TRIM28,UHRF2,RNF38,STK11,TRIM32,FBXL3,SMURF1,DDX58,NKD2,UBE4A,WWP2,RFWD3,HUWE1,ZNRF2,FBXO7,LTN1,UBE3C,RNF135,LRSAM1,UBE2M,RNF5,RFFL,ANAPC2,PLEC,SYVN1,UBE4B,TRIM26,ACOX1,SIAH2,RNF14,SSSCA1,RNF114 |
| 4.859e-06 | -12.23 | MORF_SS18 | MSigDB lists | MORF_SS18 | 58 | 23 | 17377 | 2626 |
PRKCSH,DRAP1,AGPAT1,CDK13,NFATC2IP,MTX1,PCGF1,PARN,PDXDC1,SSR1,MFN2,SEC31A,TAF2,SMAD2,CHD3,PIK3R2,MEA1,NUP62,B4GALT3,CPSF4,ZBTB11,DDB1,CSNK1D |
| 4.868e-06 | -12.23 | GSE34205_HEALTHY_VS_FLU_INF_INFANT_PBMC_UP | MSigDB lists | GSE34205_HEALTHY_VS_FLU_INF_INFANT_PBMC_UP | 172 | 49 | 17377 | 2626 |
KCTD7,RAB14,ST13,RPLP2,MUM1,EIF3D,NACA,ANKH,GSPT2,RPL15,EZH1,PABPC4,KIAA1147,EEF2K,RPL19,FBL,TOP1MT,EEF1D,EIF3L,ARHGAP17,RPL35,POLR2L,PBXIP1,BAZ2A,ZMYND11,RPS10,RPL8,RPL38,TUFM,UBE4B,ESYT1,DTWD1,NAP1L1,WDR11,RPL32,TMED10,QARS,RPS14,ODF2,ERGIC3,EIF2D,RPLP1,GALNT10,YY1,MAPK1,PTDSS1,LRP8,ZMAT3,PTOV1 |
| 4.876e-06 | -12.23 | SPTBN1 (spectrin beta, non-erythrocytic 1) | protein interactions | 6711 | 135 | 43 | 17029 | 2761 |
UNK,MAPRE1,CYLD,EWSR1,ADD1,RBM8A,MYH9,CUL1,CSNK2A1,NENF,PRKACA,MAPK14,RPA2,SHC1,EIF4A3,PTEN,MCM5,PIK3R2,CEP63,DCTN1,SPTAN1,CDC5L,CPNE1,MOB4,MYBL2,CUL3,SEPT8,BRCA1,CAPZA2,ANLN,STYXL1,EIF3H,EPB41,RPA1,SH3BP5,SMAD2,MYO18A,STAT1,CDK2,ARRB2,SMURF1,SMAD4,CAPN1 |
| 4.884e-06 | -12.23 | Set (SET nuclear oncogene) | protein interactions | 56086 | 62 | 25 | 17029 | 2761 |
PWWP2A,ASH1L,ZNF445,DDX24,UBN1,ZFP91,KAT7,ZMYND11,SUGP2,ZNF574,WDR5,MEN1,RFC2,TRIM28,MATR3,RRP36,ZBTB21,ZKSCAN1,BAZ1B,RBBP4,ZBTB11,ZNF770,ZC3H3,CDKN2A,ZBTB24 |
| 4.896e-06 | -12.23 | methylation | biological process | GO:0032259 | 299 | 75 | 17256 | 2622 |
ASH1L,DNMT3A,NOP2,KMT2E,SUZ12,CXXC1,NSD3,SNRPD3,TET3,KMT5C,THADA,METTL14,FAM86C1,DNMT1,FTSJ3,ARID4A,CARM1,MRM2,METTL1,BAZ2A,SNRPB,BTG2,EHMT1,NSUN2,METTL2A,WDR82,ICMT,KDM1B,KMT2C,TRIM28,MAT2A,PRDM11,DOT1L,WDR4,CAMKMT,OGT,FTSJ1,BEND3,RPS2,MECP2,TRMT6,RAB6A,EZH1,WDR5,RLF,METTL3,MAT2B,GTPBP3,IRF4,SUV39H2,KMT5A,CMTR2,PRDM4,ZNF335,CTR9,AHCY,FBL,NSUN4,MRM3,HEMK1,MTA2,METTL5,ARMT1,RTF1,METTL22,PRMT2,MEN1,KDM3A,MTR,GNAS,SETD3,KMT2B,PRMT7,TRMT10B,GCSH |
| 4.902e-06 | -12.23 | UFC1 (ubiquitin-fold modifier conjugating enzyme 1) | protein interactions | 51506 | 44 | 20 | 17029 | 2761 |
UNK,UBXN1,TKT,ATP6V1B2,SPR,CLNS1A,DDRGK1,NECAP2,FKBP1A,CAT,HINT1,TTC9C,UBA5,TAGLN2,TALDO1,AHCYL1,LYPLA2,SSSCA1,LDHB,USP34 |
| 4.902e-06 | -12.23 | PGM1 (phosphoglucomutase 1) | protein interactions | 5236 | 44 | 20 | 17029 | 2761 |
LDHA,ABHD11,NIT2,GALK2,OAT,APP,TERF2IP,CAT,ATIC,UBA5,MDH1,FUS,GPI,TALDO1,LTA4H,GPD1L,TERF1,POT1,LDHB,FUBP1 |
| 4.935e-06 | -12.22 | nucleolar part | cellular component | GO:0044452 | 180 | 50 | 18223 | 2701 |
KDM4A,POLR2K,RAE1,MRI1,IP6K2,UBE2I,CHD1,RPAIN,YY1AP1,NOL11,CD3EAP,UTP18,JAZF1,POP7,POLR1B,FBL,MAP3K14,ZNRD1,UTP4,CDK12,EEF1D,EIF3L,DEAF1,CDKN2AIP,USO1,POLR2L,PSPC1,UTP15,EZR,SUPT20H,KLF6,GAR1,TWISTNB,UBTF,TIMM13,DSN1,SPATA2,TBL3,CHCHD1,CDCA7L,PRMT7,DUSP11,TCOF1,MBD6,RRS1,BTBD10,AKNA,COIL,TERF1,CCDC137 |
| 4.940e-06 | -12.22 | Ubiquitin mediated proteolysis | KEGG pathways | ko04120 | 137 | 43 | 7161 | 1149 |
UBE2D3,UBE2E2,TRIP12,XIAP,UBE2Q1,UBE2Z,CUL1,UBE4A,UBE2I,BIRC2,WWP2,HERC3,FANCL,MDM2,UBE2Q2,SIAH1,HUWE1,PPIL2,ANAPC7,UBE3B,UBE3C,UBE2M,PRPF19,UBE2QL1,BIRC3,RBX1,VHL,CUL3,ANAPC2,UBE4B,BRCA1,SYVN1,CDC23,CDC16,KEAP1,CDC27,PIAS2,PML,TRIM32,UBE2C,SMURF1,ANAPC4,DDB1 |
| 4.940e-06 | -12.22 | Ubiquitin mediated proteolysis | KEGG pathways | hsa04120 | 137 | 43 | 7161 | 1149 |
UBE2D3,UBE2E2,TRIP12,XIAP,UBE2Q1,UBE2Z,CUL1,UBE4A,UBE2I,BIRC2,WWP2,HERC3,FANCL,MDM2,UBE2Q2,SIAH1,HUWE1,PPIL2,ANAPC7,UBE3B,UBE3C,UBE2M,PRPF19,UBE2QL1,BIRC3,RBX1,VHL,CUL3,ANAPC2,UBE4B,BRCA1,SYVN1,CDC23,CDC16,KEAP1,CDC27,PIAS2,PML,TRIM32,UBE2C,SMURF1,ANAPC4,DDB1 |
| 4.940e-06 | -12.22 | RIZ_ERYTHROID_DIFFERENTIATION | MSigDB lists | RIZ_ERYTHROID_DIFFERENTIATION | 74 | 27 | 17377 | 2626 |
CCNC,SP3,MAX,RAB7A,MYBL2,DHX9,CTCF,AURKB,BRCA1,BLM,MCM2,RAB1A,POLG2,MBD4,CBX3,POLR2J,RBL1,MCM5,ARNTL,TFDP1,STAT1,PIAS2,E2F1,HMGB2,SMARCE1,DNMT1,TERF2 |
| 4.958e-06 | -12.21 | GO_TRANSLATIONAL_ELONGATION | MSigDB lists | GO_TRANSLATIONAL_ELONGATION | 108 | 35 | 17377 | 2626 |
MRPL9,MRPL42,RPLP2,MRPS15,MRPL39,MRPS26,SECISBP2,GFM2,MRPL19,EEF2K,MRPL50,MRPS27,MRPL34,MRPL54,MRPL40,MRPL48,MRPL21,MRPL11,MRPL32,EEF1D,EIF5A,MRPL12,TUFM,MRPL43,MRPS10,MRPL16,MRPS14,MRPL2,DAP3,MRPL55,CHCHD1,MRPL27,RPLP1,MRPL13,MRPL3 |
| 4.958e-06 | -12.21 | HALLMARK_UNFOLDED_PROTEIN_RESPONSE | MSigDB lists | HALLMARK_UNFOLDED_PROTEIN_RESPONSE | 108 | 35 | 17377 | 2626 |
CXXC1,PARN,PAIP1,DNAJB9,SSR1,KIF5B,SEC11A,SHC1,SLC1A4,IARS,EIF4A3,BANF1,EXOSC1,DCP1A,GEMIN4,ALDH18A1,PDIA6,ATP6V0D1,PREB,DCTN1,EXOSC9,SERP1,TARS,SEC31A,YIF1A,MTHFD2,RPS14,TATDN2,H2AFX,CEBPG,KHSRP,CNOT6,ATF6,YWHAZ,SPCS3 |
| 4.958e-06 | -12.21 | GO_KINETOCHORE | MSigDB lists | GO_KINETOCHORE | 108 | 35 | 17377 | 2626 |
ZNF207,SKA3,PPP1R12A,HJURP,DYNLL1,DCTN2,CENPF,NUF2,KIF2C,PMF1,CCNB1,CSNK1A1,PSEN1,SPAG5,MIS12,AHCTF1,NUP107,KIF22,SS18L1,KNTC1,CENPM,NUP85,SEH1L,DCTN1,PLK1,RANGAP1,WDR81,AURKB,SEPT7,PHF6,KIF18A,DSN1,BIRC5,CENPT,NDE1 |
| 5.002e-06 | -12.21 | nucleobase-containing compound catabolic process | biological process | GO:0034655 | 408 | 96 | 17256 | 2622 |
ADA2,RPLP2,RBM8A,ADPGK,SND1,PAIP1,PABPC4,EDC3,RPL23A,MBD4,RPL11,CSDE1,EIF4A3,METTL14,DUT,EXOSC1,RNASEH2A,OGG1,ENPP4,RPL29,RPL35,EXOSC6,POLR2G,RPL38,POLR2D,RNPS1,OGDH,RPS9,RPSA,RPL37,PPP2CA,HINT1,RPS27A,LSM6,RPS14,NT5C3B,RPLP1,DHTKD1,SMG9,NUDT11,RPS26,PFKP,GALK1,RPS15,RPS2,GSPT2,TATDN3,RPL15,THRAP3,PARN,CNOT11,METTL3,CNOT3,TUT4,NEIL2,PRPF18,EXOSC7,RPL17,PPP1R8,PELO,DCP1A,RPL19,UPF2,AHCY,CNOT6L,PABPC1,SAMD4B,RNASEH2C,TRIR,NUDT4,RPL6,LDHA,RPL8,RPS10,RPS24,EXOSC9,PKM,PDE3B,RPL27A,PATL1,RPL36,HSPA1B,CNOT9,KPNA1,UPF1,RPL32,TATDN2,KHSRP,CNOT6,HMGB2,DDX5,DNPH1,GPI,TATDN1,PGAM1,NUDT3 |
| 5.004e-06 | -12.21 | Formation of TC-NER Pre-Incision Complex | REACTOME pathways | R-HSA-6781823 | 54 | 23 | 10287 | 1696 |
COPS8,USP7,HMGN1,POLR2I,POLR2G,POLR2L,POLR2K,RBX1,XAB2,PPIE,POLR2D,POLR2A,POLR2J,RPS27A,XPA,COPS7B,TCEA1,AQR,COPS6,ZNF830,GTF2H2,DDB1,PRPF19 |
| 5.010e-06 | -12.20 | GO_DAMAGED_DNA_BINDING | MSigDB lists | GO_DAMAGED_DNA_BINDING | 62 | 24 | 17377 | 2626 |
ERCC1,POLK,BRCA1,DCLRE1C,MPG,NEIL2,RPA1,XRCC5,RAD23A,RPA2,PCNA,RAD18,NEIL3,RAD23B,XPA,MSH2,H2AFX,HMGB2,CRY2,RUVBL2,OGG1,MSH6,DDB1,POLQ |
| 5.036e-06 | -12.20 | Gap-filling DNA repair synthesis and ligation in TC-NER | REACTOME pathways | R-HSA-6782210 | 65 | 26 | 10287 | 1696 |
USP7,HMGN1,RFC3,POLR2I,POLR2G,POLR2L,POLR2K,RBX1,POLK,XAB2,PPIE,POLR2D,RFC2,POLR2A,RPA1,RPA2,PCNA,POLE,POLR2J,RPS27A,TCEA1,AQR,ZNF830,GTF2H2,DDB1,PRPF19 |
| 5.037e-06 | -12.20 | GO_GOLGI_CISTERNA_MEMBRANE | MSigDB lists | GO_GOLGI_CISTERNA_MEMBRANE | 70 | 26 | 17377 | 2626 |
MOB4,NAGPA,B3GALT6,GOLIM4,TMEM115,GOLPH3L,APH1A,B4GALT5,B4GALT1,TMED3,B4GALT4,BCAP31,RAB21,NUCB1,GALNT2,ASAP2,GOLGA2,GOLGA8A,FUT8,ARAP1,CANT1,ST3GAL2,B4GALT3,CHPF2,B4GALT2,TMED2 |
| 5.037e-06 | -12.20 | SESTO_RESPONSE_TO_UV_C8 | MSigDB lists | SESTO_RESPONSE_TO_UV_C8 | 70 | 26 | 17377 | 2626 |
CYFIP1,PPP3CA,TOMM20,SLC2A1,SEPT8,FXR1,REEP5,SDHA,APP,PTPRF,DST,FGFR3,EPRS,PON2,MTHFD2,PPP2R5A,TMED10,GLG1,MRPS27,KIFAP3,TTC3,PFKP,ALDH9A1,TMEM131,PTPRK,FDFT1 |
| 5.081e-06 | -12.19 | FOS (Fos proto-oncogene, AP-1 transcription factor subunit) | protein interactions | 2353 | 157 | 48 | 17029 | 2761 |
NCOR2,PPP1R12A,NQO1,TSC22D3,RPS6KA1,SUMO2,NACA,CSNK2A1,UBE2I,PRKACA,ETS1,APP,LMNA,GTF2F1,RB1,USF1,NFATC3,KDM2A,AHCY,ATF2,SMARCE1,STAT3,ANKHD1,UTP4,NCOA2,CARM1,EEF1D,TRAPPC13,GLO1,NFATC2,NFATC2IP,ELK1,OPTN,DDX17,ETS2,FAAP100,KBTBD7,STAT1,PML,CEBPG,KHSRP,ANP32E,NCOA1,CLU,CHEK2,USF2,MAPK1,SMARCD1 |
| 5.086e-06 | -12.19 | GO_REGULATION_OF_RNA_STABILITY | MSigDB lists | GO_REGULATION_OF_RNA_STABILITY | 135 | 41 | 17377 | 2626 |
DHX9,THRAP3,MAPK14,PSMD9,PARN,METTL3,PAIP1,PSMD2,PSMD1,PSMA6,EXOSC7,METTL14,EXOSC1,AXIN2,DCP1A,ANP32A,YBX1,TARDBP,CNOT6L,PABPC1,EXOSC6,PSMA8,PSMB7,CIRBP,PSMA1,EXOSC9,PSMB9,RBM38,PSMB3,PSMC4,UPF1,SYNCRIP,RPS27A,HNRNPR,PSMD3,PSMD8,E2F1,KHSRP,YWHAZ,RNASEL,PSMC1 |
| 5.088e-06 | -12.19 | GSE6259_BCELL_VS_CD4_TCELL_DN | MSigDB lists | GSE6259_BCELL_VS_CD4_TCELL_DN | 177 | 50 | 17377 | 2626 |
WSB2,UBL3,MAPRE1,NACA,PRKAA1,NIPA2,NOTCH2,C2orf49,APH1B,RUFY1,MAD2L2,MIS12,DNAJB9,CD59,FGFR3,NEK6,HADHB,PRC1,RPL19,SLC26A2,ALDH18A1,MTPN,TRIM14,FYTTD1,USO1,TCTEX1D2,CELSR2,PIGT,ZNF512,RDH10,PCGF6,POLR3GL,SSR2,ARID1A,AZI2,VKORC1,CBFB,DHX15,ZFR,KIF2A,RAD51C,CCDC6,MFAP1,HNRNPH3,NFIL3,ITGB1,CBWD1,PITPNA,CHMP4B,BTF3 |
| 5.088e-06 | -12.19 | GSE9509_LPS_VS_LPS_AND_IL10_STIM_IL10_KO_MACROPHAGE_20MIN_DN | MSigDB lists | GSE9509_LPS_VS_LPS_AND_IL10_STIM_IL10_KO_MACROPHAGE_20MIN_DN | 177 | 50 | 17377 | 2626 |
POLA2,COMMD10,PPIB,TMED7,UBE2E2,CLSPN,POLR2K,KIF23,B4GALT1,MAP1LC3B,STMN1,MIS12,NDUFS4,FBXO5,MCTS1,DTL,OIP5,CCNA2,DAD1,KIF14,ARL6IP1,AKR1B1,MDFIC,C12orf75,POLR2I,POLR2G,MYBL2,CKAP2L,CDCA2,ICMT,ANLN,SHCBP1,KIF11,TWISTNB,HMGN2,FAS,BOLA3,DSN1,KIF18B,ORMDL2,PFDN4,WDR4,KPNA2,MRPL13,TMEM14A,CCNB2,UBE2C,ESPL1,VPS29,NXT2 |
| 5.116e-06 | -12.18 | WD_REPEATS_REGION | prosite domains | PS50294 | 240 | 59 | 12060 | 1670 |
WSB2,CORO7,CDC40,COPA,TRAF7,RAE1,WDR13,POC1A,WDTC1,STRN4,WDR5,GNB2,WDR48,COPB2,DTL,WDR44,UTP18,FBXW2,TAF5L,CORO1A,UTP4,STRAP,SEH1L,CSTF1,WDR41,PRPF19,MLST8,PREB,DCAF6,WDR1,DCAF8,WDR18,SMU1,UTP15,WDHD1,WDR82,WDR81,PPWD1,ARPC1A,EML4,GEMIN5,SEC31A,PLAA,BRWD1,SCAP,TBL3,CORO1C,WDR59,WDR4,DCAF11,WDR7,PRPF4,DMWD,RBBP4,WDR91,WDR62,BRWD3,DCAF5,AAAS |
| 5.139e-06 | -12.18 | whole membrane | cellular component | GO:0098805 | 1629 | 304 | 18223 | 2701 |
TMED7,RAB14,ADAM10,ABCC10,TMEM109,TAP1,TGOLN2,SYNRG,CMTM6,PARK7,GLMP,NAPG,DBNDD1,RAB4A,AP1M1,DNM2,AP2B1,CISD2,MARCH2,SEH1L,KCNAB2,BAK1,USO1,NRAS,ATG9A,MCL1,NUTF2,SLC17A5,MCFD2,SLC25A5,RAB22A,PLEKHF2,STOML2,AHNAK,WDR11,TMED10,RPS27A,ITGB1,ATP6V0C,SVIP,DNAJC5,GGA1,HLA-E,CCZ1,ACAP1,RAB23,B4GALT1,PXMP2,MAN2B1,TMED3,TMEM165,PSEN1,VPS25,COPG2,COPB2,CFLAR,TMEM179B,CD59,SNX18,ZNRF2,ATP6V0A2,PIKFYVE,GNAI2,LPCAT1,TMED2,EIF5A,SIGMAR1,RB1CC1,ADRB2,MTX1,TOMM40,MAP2K2,RHOB,CYB5A,AKAP1,PI4K2A,FAS,CAT,SEC31A,SCARB2,OSBPL11,NSF,CSK,APPL2,WIPI2,SNX14,EXOC3,RHOG,ABCA3,RAB11B,RAF1,RAC1,GPR89A,VTI1A,STARD7,BCL2L1,AP1B1,SNN,SLC25A44,PRKACA,STAM,CPNE3,APP,GNB2,CD320,MOAP1,RAB21,APLP2,MTMR4,CLCN6,BRI3,TAP2,MAVS,ATF2,TMEM9,TMBIM1,ATP6V1G1,ENPP4,SNX8,CPNE1,GOPC,VDAC2,ATP6V0A1,RAB1A,ANKZF1,ALDH3B1,PEX5,CHMP4A,DDOST,RAB24,CORO1C,TICAM1,LRP8,TUBB,ANXA6,MANBA,FLOT1,ATG2B,FOXO3,RAB11A,HLA-A,PIP5K1C,CAPN2,MTX2,TPCN1,MFSD12,LDHB,KCNQ1,RHOT1,PICALM,SPPL2B,FADD,SH3GLB1,HGS,KIF18A,MAGT1,ATP5MC3,CCZ1B,WNT5B,ACOX1,PML,LRPPRC,PSAP,WDR91,WDR45B,VPS29,SNAPIN,MTX3,COPA,SEC16A,MAP1LC3B,RUFY1,BECN1,BIRC2,PCYOX1L,PRNP,RAB8A,RAP1A,RAB35,SLC44A1,HADHB,SRI,ZFYVE27,TRIM14,DRAM2,WDR41,MIOS,CYSTM1,EZR,RAB5B,RHEB,OPTN,NECAP2,AGPAT2,GRIPAP1,VPS4A,CLN3,ATP6V0E1,STARD3NL,UBE2D3,PHB2,LAMTOR3,CDIP1,RAB6A,TIGAR,VMP1,BCL2,TMEM8A,ATP6V0D1,KDELR1,ABCC1,ACSL3,GBA,KRAS,APPL1,RMC1,DAPK3,SNAP23,LAMTOR4,NUP62,CTSA,EHD4,NIPSNAP2,UNC13C,SNX27,CHMP2A,TOMM20,GNPNAT1,DYNLL1,SLC2A1,COPE,RRAGC,ZFYVE21,ATP6V1B2,LYN,MIEF1,ATP6V0B,MDM2,SAR1A,WDR44,RPN2,CORO1A,CYB5R1,LMAN1,CLTB,F2R,ACSL5,SNX25,CLCN3,BIRC3,PPT1,SELPLG,RAB7A,BICD2,CHMP2B,VDAC1,PEF1,ATP1A1,SURF4,SCAP,TAB2,STAT6,TOMM6,WDR59,AP1S1,CHMP4B,SCARB1,MAPK1,AP2S1,ABCA1,GOLIM4,SCYL1,VPS45,TMX3,LETMD1,GGA2,SCYL2,TFRC,SPPL2A,SEC24C,ZDHHC13,ABCD1,CAMK2G,ADAM17,RHOA,MLEC,ACP2,SNX2,RFFL,PNPLA8,WDR81,RHOT2,NEU1,MFN2,MAPK3,HLA-B,RAB18,ATP6V1D,PDCD6,SEC23IP,SNAP29,PGRMC1,ATP6V1C1,CHMP7 |
| 5.168e-06 | -12.17 | NOUZOVA_TRETINOIN_AND_H4_ACETYLATION | MSigDB lists | NOUZOVA_TRETINOIN_AND_H4_ACETYLATION | 126 | 39 | 17377 | 2626 |
MBD1,NDUFA5,RECQL,PNISR,THOC1,ENSA,LETMD1,THRAP3,IP6K2,CNTROB,USP48,ZNF518A,MCTS1,KRR1,PDCD10,PSMA6,NSRP1,BANF1,KNTC1,MTPN,TXNL1,CLPTM1,YTHDC1,ERCC1,CDC123,SLC26A6,GORAB,NUP155,CHMP2B,SHCBP1,KDM3A,GOSR1,MARK2,EIF3H,PSMC4,CDCA5,MPV17,CHMP4B,NAA20 |
| 5.211e-06 | -12.16 | positive regulation of ubiquitin-dependent protein catabolic process | biological process | GO:2000060 | 99 | 33 | 17256 | 2622 |
SUMO2,NKD2,SIRT2,UBQLN2,CSNK1A1,PSEN1,BCAP31,ANKIB1,FBXO22,DDRGK1,USP5,RAD23A,MDM2,PTEN,RNF19A,SOCS5,PLK3,PLK1,LONRF3,RBX1,GBA,HSPA1B,HSPBP1,KEAP1,AXIN1,SOCS4,DVL1,CLU,RNF14,SMURF1,RNF139,CSNK1D,RNF114 |
| 5.267e-06 | -12.15 | RB1 (RB transcriptional corepressor 1) | protein interactions | 5925 | 258 | 70 | 17029 | 2761 |
CCNC,USP7,DNMT3A,THOC1,FOXM1,KDM4A,RAF1,SMARCA4,IRF3,CCNB1,UBE2I,MAPK14,LIN9,CDK5,PA2G4,MDM2,CCNA2,KDM2A,KMT5C,RABGAP1L,ATF2,DNMT1,RPRD1B,ARID4A,SP3,BRD4,AATF,EID1,E2F3,NFATC2,AURKB,BRCA1,PRKRA,UBTF,CDC16,BRD2,RBL1,E2F4,UHRF2,CHEK2,TFDP2,E2F2,MAPK1,FAM208A,CBX4,HDAC2,CASP6,TCF3,CDK13,FOXO3,LMNA,PNO1,RB1,STAT3,PPAN,FOXK1,CREG1,LDB1,ANAPC2,PRMT2,FAS,CDC27,BIRC5,TFDP1,E2F1,PML,RBBP4,YY1,CDK2,PURA |
| 5.275e-06 | -12.15 | G1 to S cell cycle control | WikiPathways | WP45 | 68 | 26 | 5312 | 837 |
POLA2,PRIM2,E2F3,ORC1,CCNB1,MCM2,RPA1,PRIM1,RPA2,CDKN2C,RB1,PCNA,MDM2,POLE,RBL1,E2F4,MCM5,TFDP1,E2F1,CDKN1B,CREB1,ORC3,TFDP2,E2F2,CDK2,CDKN2A |
| 5.294e-06 | -12.15 | GSE9988_LOW_LPS_VS_VEHICLE_TREATED_MONOCYTE_DN | MSigDB lists | GSE9988_LOW_LPS_VS_VEHICLE_TREATED_MONOCYTE_DN | 182 | 51 | 17377 | 2626 |
RHOG,CYTIP,HECA,DNAJC5,PHF23,TSC22D3,RPS6KA1,DYNLL1,SUMO2,KLF13,DAZAP2,TWF2,PCBP1,SDHA,GIT2,PIP5K1C,PHC2,WDR44,FBXO7,CAPZA1,BRI3,CTDSP2,TMBIM1,S100A6,MED22,DNAL4,ORAI2,PPP1R9B,EIF3L,PPP1R18,FOXK1,TACC1,ATG9A,FRAT2,WDR82,MAP7D1,USP22,ICMT,IRF5,MYO1F,TFEB,DDX17,HHEX,CSK,BAZ1B,ZDHHC7,STK11,WIPI2,PSAP,RBPJ,PURA |
| 5.294e-06 | -12.15 | GSE17721_LPS_VS_PAM3CSK4_8H_BMDC_DN | MSigDB lists | GSE17721_LPS_VS_PAM3CSK4_8H_BMDC_DN | 182 | 51 | 17377 | 2626 |
UBL3,PPIB,NOP2,MRPS2,PRKCSH,STARD7,SMC6,MYO9B,CLCC1,EIF2AK4,KRR1,ANKRD28,KRI1,ATP6V0B,SMC3,ATP2A2,AHSA1,BTF3L4,YBX1,GLTP,AQR,MRPL11,EIF5,CLTB,PDIA6,KCNAB2,EEF1D,SLC39A9,EIF3L,NXT1,RNASEH2C,NSUN2,RDH10,WBP2,RPS10,HTATIP2,BMS1,GALK2,NDUFA7,WBP1,GFER,EIF3H,CYB5A,CAT,CORO1C,CAPN7,FTSJ1,MRPL3,ADAM23,FUBP1,SNAPIN |
| 5.294e-06 | -12.15 | GSE14000_UNSTIM_VS_16H_LPS_DC_TRANSLATED_RNA_UP | MSigDB lists | GSE14000_UNSTIM_VS_16H_LPS_DC_TRANSLATED_RNA_UP | 182 | 51 | 17377 | 2626 |
NDUFA5,GMFG,TRERF1,GXYLT1,SRSF6,VPS45,RACGAP1,NFATC3,YIF1B,TTC3,ANAPC7,AHCY,CYB5R1,MRPL48,APOOL,TTLL12,GPD1L,TMEM9,CAMK2G,TACC3,PDLIM2,AMPD2,CYFIP1,ERMP1,FAM172A,TIMMDC1,EMB,KIAA0930,LRRC8A,FRAT2,ARHGDIB,UBE4B,USP22,SOCS7,MAN2A2,PWWP2B,SLC19A1,TSC1,PEX5,TTC13,ELMO1,CCDC6,LRPPRC,CHEK2,RUVBL2,SPCS3,PREPL,RRS1,OSGEPL1,ZMAT3,MRPL3 |
| 5.294e-06 | -12.15 | GSE14908_ATOPIC_VS_NONATOPIC_PATIENT_HDM_STIM_CD4_TCELL_UP | MSigDB lists | GSE14908_ATOPIC_VS_NONATOPIC_PATIENT_HDM_STIM_CD4_TCELL_UP | 182 | 51 | 17377 | 2626 |
HIVEP3,PIGM,LZTR1,RPS2,SARNP,BABAM1,GPR89A,GNE,GLRX3,LYRM2,PCBP1,CPNE3,SAC3D1,RNF121,RAP1A,EI24,NFU1,KCNAB2,TMX1,KDELR1,ALDH9A1,COPS8,ERCC1,AATF,TMEM39A,POLK,NSDHL,E2F3,SEPT7,C9orf40,EDEM2,TSR2,EIF3A,CYB5A,MAPK3,SURF4,GOLGA7,STT3A,NSMCE2,NDUFA11,ITGB1,SNRPG,TMEM101,GAS2,IDH3B,RTN3,CHID1,ZMAT3,GPR89B,DDB1,PDF |
| 5.294e-06 | -12.15 | GSE22886_NAIVE_VS_IGG_IGA_MEMORY_BCELL_DN | MSigDB lists | GSE22886_NAIVE_VS_IGG_IGA_MEMORY_BCELL_DN | 182 | 51 | 17377 | 2626 |
KCTD7,LIME1,DAP,DYNLL1,FAM129A,TOR3A,NANS,SND1,AP3S1,MFSD10,TFRC,CFLAR,PTPN2,CAPN2,GSTK1,SUB1,MZT2A,DPYSL2,ANXA5,MVP,PPA1,TMBIM1,S100A6,LDHB,VOPP1,AMPD2,SEC61B,KLF10,DENND1B,NQO2,RPL27A,PSMB9,ISG15,EIF3A,MYO1F,AHNAK,ATP1A1,ORMDL2,PRDX3,TFDP1,PPA2,ITGB1,RPLP1,CAB39,ACAT1,UQCRH,CTSA,ZMIZ1,YWHAH,TMEM14A,TUBB |
| 5.299e-06 | -12.15 | organophosphate biosynthetic process | biological process | GO:0090407 | 537 | 120 | 17256 | 2622 |
RAB14,PIGM,KARS,PPCS,SUCLG1,PIGQ,HEXB,UCK2,AGPAT1,STARD7,CSNK2A1,UCK1,CHKB,SLC35B2,ADPGK,CDIPT,LCLAT1,ATP5PF,GGPS1,RUFY1,CPNE3,FLAD1,MTMR4,DUT,PIK3R2,ADCY9,SLC44A1,RAB4A,LPIN2,PPCDC,UPRT,SLC26A2,GPD1L,ADCY7,PGAP2,CPNE1,CGAS,DPM1,ATP6V0A1,MTMR6,RRM2,OGDH,TAZ,PRPSAP1,STOML2,ABHD5,AGPAT2,GUCY1B1,DHTKD1,MBOAT1,PDXK,CHPT1,MAPK1,PFKP,GALK1,NADSYN1,COX5B,CDS2,PIGN,RRM1,TKT,AGPAT3,ARF1,ATP5F1B,IP6K2,PMVK,PIP4K2A,HDDC2,PIP5K1C,CHKA,FGFR3,PDXP,ERH,NUS1,GART,PTEN,PYURF,ATIC,PTPN11,CTPS1,PIGG,ATP6V0A2,CYC1,PCYT2,PIKFYVE,LPCAT1,RNLS,AMPD2,TGFB1,TK1,GUK1,PIGT,PGS1,LDHA,PIP4K2C,NADK2,ADSL,DCTD,MTMR12,PKM,ATP5MF,PI4K2A,MTMR3,ADSS,MBIP,ATP5MC3,DCK,PRPS2,LPCAT4,TBPL1,NAXE,IMPDH1,ACAT1,SAMD8,GPI,ATP5F1A,NIPSNAP2,PARP10,PGAM1,PTDSS1 |
| 5.308e-06 | -12.15 | MEINHOLD_OVARIAN_CANCER_LOW_GRADE_DN | MSigDB lists | MEINHOLD_OVARIAN_CANCER_LOW_GRADE_DN | 20 | 12 | 17377 | 2626 |
MRPL9,NCK1,KIF14,SNRPB,STAT1,TPX2,COX8A,JTB,STARD7,CCNB2,CFL1,RHEB |
| 5.322e-06 | -12.14 | positive regulation of chromosome segregation | biological process | GO:0051984 | 26 | 14 | 17256 | 2622 |
RB1,RAD18,NSMCE2,CDT1,CUL3,SMC6,H2AFY,CDC6,SIRT2,CCNB1,BECN1,SLF1,ESPL1,SLF2 |
| 5.330e-06 | -12.14 | Golgi vesicle budding | biological process | GO:0048194 | 78 | 28 | 17256 | 2622 |
USO1,TRAPPC9,GOLPH3L,GORASP1,CUL3,MCFD2,RAB1A,PEF1,SEC16A,ANKRD28,SEC31A,CD59,SEC23IP,PDCD6,GOLGA2,NSF,TMED10,SAR1A,SEC24C,MYO18A,PPP6C,PPP6R3,TFG,LMAN1,PPP6R1,TMED2,CSNK1D,PREB |
| 5.337e-06 | -12.14 | spliceosomal complex assembly | biological process | GO:0000245 | 58 | 23 | 17256 | 2622 |
YTHDC1,SNRNP200,SRSF6,SF3B1,CRNKL1,USP39,SRSF5,SNRPD3,PRPF39,TXNL4A,LUC7L,SF3A2,SRSF1,DDX23,RBMX,LUC7L3,GEMIN6,KHDC4,SNRPG,LUC7L2,SRSF10,PRPF19,SRPK2 |
| 5.343e-06 | -12.14 | kinetochore | cellular component | GO:0000776 | 133 | 40 | 18223 | 2701 |
ZNF207,SKA3,HJURP,PPP1R12A,DYNLL1,CDT1,CENPF,DCTN2,NUF2,KIF2C,PMF1,CCNB1,SPDL1,CSNK1A1,PSEN1,MEAF6,MIS12,SPAG5,AHCTF1,NUP107,KIF22,SS18L1,CENPM,KNTC1,NUP85,SEH1L,DCTN1,PLK1,RANGAP1,AURKB,SEPT7,PHF6,CENPU,KIF18A,DSN1,FBXO28,BIRC5,CENPT,NDE1,DYNC1LI2 |
| 5.424e-06 | -12.12 | SESTO_RESPONSE_TO_UV_C0 | MSigDB lists | SESTO_RESPONSE_TO_UV_C0 | 104 | 34 | 17377 | 2626 |
HSPH1,POLR2K,DYNLL1,TAP1,NDUFA4,DAZAP2,RBM4,TFRC,PRNP,RAB21,PCNA,EIF4A3,ARL6IP1,CTR9,CITED2,EIF5,CDC37,PPIF,SP3,HARS,USP10,RIT1,DNAJA1,MCFD2,EIF4G2,NEU1,POLR2A,TRIM26,KPNA4,BRD2,PGRMC1,KPNA2,ATP6V0C,YWHAH |
| 5.424e-06 | -12.12 | REACTOME_SIGNALING_BY_EGFR_IN_CANCER | MSigDB lists | REACTOME_SIGNALING_BY_EGFR_IN_CANCER | 104 | 34 | 17377 | 2626 |
TSC2,ADAM10,RAF1,EPN1,AKT1S1,PRKACA,FOXO3,STAM,CALM2,MDM2,SHC1,CDC42,PTEN,ADCY9,CDKN1B,AP2B1,CREB1,CDC37,ADCY7,MLST8,PDPK1,NRAS,ADAM17,AKT2,PRKAR1B,KRAS,MAP2K2,MAPK3,HGS,RPS27A,CSK,MAPK1,HRAS,AP2S1 |
| 5.448e-06 | -12.12 | Huntington's disease | KEGG pathways | ko05016 | 187 | 54 | 7161 | 1149 |
NDUFA5,COX5B,NDUFV2,NDUFS1,NDUFB6,POLR2K,UQCR10,DCTN2,COX4I1,NDUFA4,CYCS,ATP5F1B,ATP5PF,SDHA,NDUFS7,NDUFS4,NRF1,NDUFV1,NDUFA2,NDUFB4,AP2B1,NDUFS8,NDUFB9,CYC1,CLTB,CREB1,NDUFA3,DNAL4,DCTN1,PPIF,POLR2I,POLR2G,POLR2L,VDAC2,POLR2D,RCOR1,NDUFA7,NDUFB1,VDAC1,SLC25A5,POLR2A,SDHB,POLR2J,ATP5MC3,NDUFA11,COX7A2L,COX8A,TBPL1,COX5A,UQCRH,ATP5F1A,NDUFS5,AP2S1,HDAC2 |
| 5.448e-06 | -12.12 | Huntington's disease | KEGG pathways | hsa05016 | 187 | 54 | 7161 | 1149 |
NDUFA5,COX5B,NDUFV2,NDUFS1,NDUFB6,POLR2K,UQCR10,DCTN2,COX4I1,NDUFA4,CYCS,ATP5F1B,ATP5PF,SDHA,NDUFS7,NDUFS4,NRF1,NDUFV1,NDUFA2,NDUFB4,AP2B1,NDUFS8,NDUFB9,CYC1,CLTB,CREB1,NDUFA3,DNAL4,DCTN1,PPIF,POLR2I,POLR2G,POLR2L,VDAC2,POLR2D,RCOR1,NDUFA7,NDUFB1,VDAC1,SLC25A5,POLR2A,SDHB,POLR2J,ATP5MC3,NDUFA11,COX7A2L,COX8A,TBPL1,COX5A,UQCRH,ATP5F1A,NDUFS5,AP2S1,HDAC2 |
| 5.456e-06 | -12.12 | positive regulation of protein catabolic process | biological process | GO:0045732 | 215 | 58 | 17256 | 2622 |
ATXN3,GGA1,SUMO2,NKD2,CSNK2A1,SIRT2,UBQLN2,CSNK1A1,PSEN1,BCAP31,ANKIB1,FBXO22,WWP2,DDRGK1,USP5,RAD23A,DTL,MDM2,PTEN,CDKN1B,RNF19A,TIPARP,LPCAT1,SOCS5,PLK1,PLK3,ATP5IF1,LONRF3,TNFAIP3,RBX1,RAB7A,GBA,EZR,EDEM2,PTTG1IP,PSMC4,HSPA1B,KEAP1,IDE,HSPBP1,NSF,AXIN1,OAZ2,SOCS4,ADAM9,TRIM32,CLU,DVL1,CD81,SMURF1,RNF14,PSMC1,OAZ1,RNF139,CSNK1D,DDB1,RNF114,USP13 |
| 5.483e-06 | -12.11 | GSE17721_CTRL_VS_GARDIQUIMOD_0.5H_BMDC_UP | MSigDB lists | GSE17721_CTRL_VS_GARDIQUIMOD_0.5H_BMDC_UP | 187 | 52 | 17377 | 2626 |
TRIM41,DDX47,PARP12,MRPL42,ADAM10,RAC1,RRM1,TIA1,DHX8,CMTM6,XPR1,CHKA,CSDE1,KLF16,DUT,DDA1,CAPZA1,CRY2,TAF5L,AQR,TECR,MCMBP,FTSJ3,HNRNPM,SOCS5,RBM15B,VOPP1,FTL,TRAFD1,HMGN5,PARP4,NARF,PITPNB,CDC23,MCM2,CBFB,TOLLIP,NSA2,HHEX,JAK1,TMEM168,NSF,LUC7L3,CDCA7L,ITGB1,LRPPRC,ZRANB2,TAF12,HIPK3,EYA2,SNX14,CCDC137 |
| 5.483e-06 | -12.11 | GSE26343_UNSTIM_VS_LPS_STIM_MACROPHAGE_UP | MSigDB lists | GSE26343_UNSTIM_VS_LPS_STIM_MACROPHAGE_UP | 187 | 52 | 17377 | 2626 |
HIVEP3,RWDD1,RRP15,SRGN,MRI1,ARID5A,UCK2,MED13L,SND1,SNRPD3,CMTM6,RGS1,PNO1,IRF4,ERH,SUB1,GART,NOC2L,AHCY,OSTC,FBL,UBE2M,S100A6,NOL12,TGFB1,LYRM1,NSUN2,PSMB7,ATP6V0A1,TOR1AIP2,GAR1,DDX39A,EML4,SNRPA,MAT2A,C1orf131,SERTAD2,CCDC86,NFIL3,SIAH2,AEN,KLHDC4,BTF3,RBPJ,RRS1,TRAF5,NMD3,HRAS,LRP8,GPATCH4,PFKP,FUBP1 |
| 5.483e-06 | -12.11 | GSE2770_UNTREATED_VS_TGFB_AND_IL4_TREATED_ACT_CD4_TCELL_2H_DN | MSigDB lists | GSE2770_UNTREATED_VS_TGFB_AND_IL4_TREATED_ACT_CD4_TCELL_2H_DN | 187 | 52 | 17377 | 2626 |
LIME1,GMFG,MECP2,C5orf30,SMC6,HMGN3,EIF2AK4,AP1B1,DAZAP2,C19orf48,CRLF3,LCLAT1,COPG2,HMG20A,PAIP2,RAB21,VASP,AHCTF1,EXOSC7,KLF16,ARPC5,METTL14,TBC1D14,ZCCHC2,PPCDC,CORO1A,PHKG2,NIPSNAP1,VPS13B,WDR41,SNX2,EID1,VHL,WDR1,JTB,WIPF1,KRAS,ARHGDIB,STX16,COMMD4,RPS9,OPTN,ABHD5,SMAD2,TXNDC16,CCDC6,SNAP29,CAMKMT,NRM,LRPPRC,TIGD2,ADNP2 |
| 5.483e-06 | -12.11 | GSE34006_UNTREATED_VS_A2AR_AGONIST_TREATED_TREG_UP | MSigDB lists | GSE34006_UNTREATED_VS_A2AR_AGONIST_TREATED_TREG_UP | 187 | 52 | 17377 | 2626 |
SEPHS2,SMAP1,MRPL9,DEPDC1,ALKBH5,USP39,MXD4,C2orf49,AP3S1,ZADH2,RLF,STMN1,RAB11A,MOAP1,CAPN2,RPN1,SUB1,DNAJC8,ARPC5,GRSF1,MBD2,PELO,CDKN1B,PTGES3,RNF19A,TNRC18,LRRC59,CDK12,CFL1,PDPK1,CCT2,TMEM115,HELB,VDAC2,LDHA,MKI67,SMC2,SOX4,PTTG1IP,GIGYF1,EIF3H,RPSA,MTHFD2,TMED10,ZNF330,SPCS3,ATP6V1C1,IGBP1,PGAM1,HIGD2A,CSNK1D,SMNDC1 |
| 5.483e-06 | -12.11 | GSE3039_NKT_CELL_VS_ALPHABETA_CD8_TCELL_UP | MSigDB lists | GSE3039_NKT_CELL_VS_ALPHABETA_CD8_TCELL_UP | 187 | 52 | 17377 | 2626 |
INTS2,POLA2,BCCIP,IMMT,FEZ2,MRPL42,COPE,GADD45G,MRPS26,SMARCA4,NUF2,AGFG1,SLC35B1,STMN1,HDDC2,MCTS1,ANKRD28,CSDE1,GART,CTSS,UCHL5,RRBP1,TPST1,RNF19A,MRPL40,APOOL,MRPL21,MSH6,SLC25A1,FDFT1,GTF3C6,CCT2,MND1,TIMP2,PRIM2,KAT2A,PSMA1,CKAP2L,WDHD1,ELP4,EIF3G,GLOD4,SLC19A1,PRDX3,PFDN4,ZNF330,MAP4,ERGIC3,APPL2,TRIM32,DDB1,ESYT2 |
| 5.483e-06 | -12.11 | GSE42724_B1_BCELL_VS_PLASMABLAST_DN | MSigDB lists | GSE42724_B1_BCELL_VS_PLASMABLAST_DN | 187 | 52 | 17377 | 2626 |
TMEM106C,GOLPH3L,SYS1,RAC1,ENSA,CHCHD2,UBQLN2,RCOR3,ABHD14A,KIAA1147,PAIP2,FBXO3,RAP1A,SMC3,PHF14,MAML1,ERI3,CAMK2G,RNF5,LDHB,SLC39A9,NIPAL3,PDPK1,NTPCR,WDR18,LDB1,TUBGCP5,UTP15,SCFD2,HTATIP2,ARHGDIB,AMDHD2,MEF2D,PCGF1,CBFA2T2,PRKRA,MAT2A,EIF3A,NCDN,OSBPL8,GLG1,APPL2,ATE1,ZFP90,PKD2,STK11,ATP6V1C1,CHMP7,TMEM14A,ZBTB11,OAZ1,HIGD2A |
| 5.483e-06 | -12.11 | GSE2770_IL12_AND_TGFB_ACT_VS_ACT_CD4_TCELL_48H_DN | MSigDB lists | GSE2770_IL12_AND_TGFB_ACT_VS_ACT_CD4_TCELL_48H_DN | 187 | 52 | 17377 | 2626 |
SRM,HSPH1,NQO1,MRPS2,RAE1,PDAP1,CDT1,DBF4,MOGS,TPX2,BLM,CDC73,REPS1,FASTKD3,PA2G4,NUS1,SUV39H2,ATIC,SLC35B4,NUP107,SOCS6,TARDBP,ERI3,CPSF4,FTSJ3,ENPP4,CDKN2AIP,MIOS,ELL2,TMEM39A,GALC,PSPC1,GTPBP4,WDHD1,DCTD,LY6E,GAR1,ARMC8,API5,SRSF1,KPNA4,CDCA4,SEC61A1,CCDC14,H2AFX,CBLN2,PITPNA,YY1,RRS1,NRBP1,HDAC2,ZNF146 |
| 5.483e-06 | -12.11 | GSE17721_CTRL_VS_LPS_6H_BMDC_UP | MSigDB lists | GSE17721_CTRL_VS_LPS_6H_BMDC_UP | 187 | 52 | 17377 | 2626 |
TMED7,GCLM,PRKAB1,TRIM41,MRPL42,THOC1,RAC1,MAGED1,UBXN1,GADD45G,CUTA,MRPS26,OLA1,LANCL1,SLC12A9,TMEM179B,CDKN2C,SMC3,CTNNBL1,ATG3,XPA,SOCS6,CTR9,RPL19,TMEM14C,ELOVL5,SEC61B,FOPNL,KAT7,TEX10,DNAJC9,UBE4B,ADRB2,BICD2,CDC23,MATR3,CLNS1A,MAPK3,ANKRD10,HHEX,SGSH,GRIPAP1,QARS,RPS14,PRPS2,MPV17,KLHDC4,PDXK,RBBP4,SNX14,NAA60,FAF1 |
| 5.483e-06 | -12.11 | GSE27786_LIN_NEG_VS_NKTCELL_UP | MSigDB lists | GSE27786_LIN_NEG_VS_NKTCELL_UP | 187 | 52 | 17377 | 2626 |
TMEM106C,MRPL42,MRPS2,C1orf112,TRMT6,PXMP2,PITHD1,APP,LMNA,LIN9,FARSA,STRBP,ATP2A2,IARS,PPP1R8,PRC1,NUP107,GEMIN6,KNTC1,LDLRAD3,ORC3,LPCAT1,TMEM9,MGAT5,PTPRK,NUDC,SGCE,TCTEX1D2,ACSL3,SEPT8,CKAP2L,HEBP2,RCOR1,DCTD,NUP155,CDCA2,AURKB,MRPL2,TWSG1,DGCR8,NIP7,NRM,MRPL27,PPM1G,BCL7C,ADAM9,FAM126A,SMPD4,DMWD,TFDP2,CDK2,MRPL3 |
| 5.535e-06 | -12.10 | GO_NUCLEOBASE_CONTAINING_SMALL_MOLECULE_METABOLIC_PROCESS | MSigDB lists | GO_NUCLEOBASE_CONTAINING_SMALL_MOLECULE_METABOLIC_PROCESS | 486 | 110 | 17377 | 2626 |
KARS,NDUFA5,COX15,DNMT3A,PPCS,TXN,NDUFB6,SUCLG1,UQCR10,MDH2,UCK2,OLA1,UCK1,ADPGK,SLC35B2,ATP6V1B2,MBD4,FLAD1,DUT,ADCY9,PPCDC,UPRT,NDUFB9,SLC26A2,AHCYL1,TALDO1,GPD1L,DNMT1,OGG1,KCNAB2,PDCL3,ADCY7,ENPP4,ATP6V0A1,PFKFB3,RRM2,NDUFA7,OGDH,ICMT,NDUFB1,TAZ,PRPSAP1,PDHX,MAT2A,STOML2,HINT1,PRDX5,NDUFA11,MLYCD,DHTKD1,COX5A,UQCRH,MAPK1,PFKP,GALK1,NDUFV2,NADSYN1,COX5B,NDUFS1,MECP2,MRI1,TKT,RRM1,NDUFA4,ABHD14B,CYCS,COX4I1,NEIL2,NDUFS7,NDUFS4,MAT2B,ERH,NDUFV1,GART,NDUFA2,NDUFB4,ATIC,MSH2,ATP6V0A2,NDUFS8,AHCY,CYC1,NDUFA3,LDHB,TGFB1,AMPD2,TK1,GUK1,NUDT4,AMD1,LDHA,ADSL,DCTD,MPG,PDE3B,HSPA1B,ADSS,CAT,DCK,PRPS2,COX7A2L,TBPL1,COX8A,IMPDH1,MDH1,NDUFS5,GPI,IDH3B,PGAM1,NUDT3 |
| 5.587e-06 | -12.09 | TBK1.DF_DN | MSigDB lists | TBK1.DF_DN | 266 | 68 | 17377 | 2626 |
PPCS,PNISR,KDM4A,ADAM10,NF1,GNPDA1,SNX15,AGFG1,BCL2L1,RBM4,KTN1,PRKD3,RRN3,ZKSCAN1,MTA1,ZNHIT6,KIF14,SLC26A2,NAA35,USP22,GALNT7,PRKRA,CHMP2B,CBFB,PSMB9,PDHX,IDE,CDCA4,BRWD1,DSN1,NIP7,LUC7L3,HIPK2,SCARB1,TSPAN5,SEPHS2,PKP4,CASP6,GNE,MED13L,KLF13,ATG2B,SIKE1,RLF,RFWD3,PPIG,BDH1,MSH2,GEMIN4,RNF5,ALDH9A1,TERF2,TTPAL,RPAP3,ELL2,DENND1B,NEK7,MTR,APPL1,NEK1,GOLGA4,CDC27,GOLGA2,DCK,ODF2,TCOF1,ATP6V1C1,HIPK3 |
| 5.596e-06 | -12.09 | MRPL50 (mitochondrial ribosomal protein L50) | protein interactions | 54534 | 106 | 36 | 17029 | 2761 |
COX15,MRPL9,CORO7,MRPL42,MRPL39,UBR2,FLOT1,MRPL19,EXOSC7,XRCC2,MRPL34,MRPL54,SUCLG2,MRPL40,MRPL48,MRPL21,MRPL11,MRM3,MRPL32,KCNAB2,MRPL57,CUL3,MRPL43,MRPL12,ATP6V0A1,MRPL16,ATP5MF,GAR1,RCC1L,MRPL2,SYNCRIP,MRPL55,MRPL27,DUSP11,MRPL13,MRPL3 |
| 5.597e-06 | -12.09 | COX5A (cytochrome c oxidase subunit 5A) | protein interactions | 9377 | 55 | 23 | 17029 | 2761 |
SLC30A9,COX5B,UNK,COA3,CHCHD2,NDUFA4,COX4I1,PPP3CB,OGDH,VDAC1,KDM1B,EPM2A,FERMT3,RAB8A,DAP3,NDUFV1,SYNCRIP,BRD2,COX7A2L,YBX1,KIF22,CYC1,COPS6 |
| 5.597e-06 | -12.09 | PPP1R7 (protein phosphatase 1 regulatory subunit 7) | protein interactions | 5510 | 55 | 23 | 17029 | 2761 |
RPAP3,USP7,PPP1R2,UBXN1,HNRNPF,PACS1,PPP1R16B,DDX17,FANCL,UBXN2A,HGS,HSPBP1,KIF18A,PDRG1,UBXN2B,PPME1,MAPK6,PQBP1,PPP1R11,TP53BP2,TTLL12,RPRD1B,VPS29 |
| 5.599e-06 | -12.09 | V$ETS_Q4 | MSigDB lists | V$ETS_Q4 | 236 | 62 | 17377 | 2626 |
TCF12,KIF3B,ZNF296,TRIM41,GGNBP2,LIME1,GMFG,SLC41A1,ZFP91,CAST,RAE1,PDAP1,ACTR3,AGPAT1,ACAP1,KLF13,CHIC2,NDUFA4,SND1,DOCK11,PPP1R16B,LYN,FOXO3,RBM4,CMTM6,VAV1,STRBP,RINL,SEC24C,PTPN11,CAPZA1,CORO1A,ZNF800,KCNAB2,PDLIM2,RLIM,ACSL5,NIPAL3,PPP1R9B,ERCC1,NASP,BAZ2A,AMD1,E2F3,MAP7D1,MTMR12,FOXRED1,ARHGAP15,C1orf122,DDX23,EIF3K,SEPT1,ITPRIPL1,SEC61A1,WDR11,ELMO1,TPP2,LPCAT4,PML,ARAP1,ARRB2,ZMAT3 |
| 5.620e-06 | -12.09 | BERENJENO_TRANSFORMED_BY_RHOA_DN | MSigDB lists | BERENJENO_TRANSFORMED_BY_RHOA_DN | 369 | 88 | 17377 | 2626 |
CHMP2A,ST13,GNPDA1,MAGED1,ANK3,RRAGC,SIRT2,SND1,HCFC1R1,MAP1LC3B,MIEN1,PRNP,DECR1,APLP2,SHC1,IL6ST,BRI3,TTC3,F2R,CLN6,CTDSP2,EID1,LRBA,ATP6V0A1,GALK2,USP22,RAB5B,GLOD4,HSPB11,RAB24,SEL1L,ST3GAL2,ACTB,GAS2,MYL12B,PDCD4,PTOV1,ADAM23,ANXA6,DAP,DNAJB2,TRIO,DCTN2,TMED3,MXD4,GGA2,AP3S1,LYRM2,RAB11A,FAM8A1,GNS,PTEN,ARF5,XPA,KIFAP3,GNAI2,SGCB,STAT3,SLC12A2,ATP6V0D1,SPTAN1,PPP3CA,NTPCR,TRAFD1,CSRP1,TSPYL4,DCAF8,EMB,GBA,VKORC1,NDRG3,CYB5A,ECH1,MAGED2,SEC31A,EPRS,PLD3,TXNDC16,LTBP4,ZHX1,ERGIC3,PKD2,CTSA,ZFP90,DTD1,ACADM,PSAP,SNAPIN |
| 5.625e-06 | -12.09 | PLRG1 (pleiotropic regulator 1) | protein interactions | 5356 | 70 | 27 | 17029 | 2761 |
XAB2,SUZ12,SF3B1,PPIE,USP42,CRNKL1,CUL3,PRPF3,SF3A2,APP,PABPC4,KPNA1,CTNNBL1,EIF4A3,UCHL5,YJU2,GPATCH1,PRPF4,KPNA2,MRPL40,AQR,ISY1-RAB43,PABPC1,IFI16,HNRNPM,CDC5L,PRPF19 |
| 5.625e-06 | -12.09 | MRPL42 (mitochondrial ribosomal protein L42) | protein interactions | 28977 | 70 | 27 | 17029 | 2761 |
DDX28,MRPL9,MRPL39,MRPL12,MRPL43,RPL6,MRPS26,ILF3,MRPL16,MRPL19,MRPL50,MRPL2,GATC,MRPL55,HNRNPR,MRPL27,MRPL34,MRPL40,MRPL48,MRPL11,MRPL21,MRPL13,MRM3,MRPL3,MRPL32,MRPL57,FUBP1 |
| 5.625e-06 | -12.09 | Srsf1 (serine/arginine-rich splicing factor 1) | protein interactions | 110809 | 70 | 27 | 17029 | 2761 |
FAM208B,SNRNP200,MPHOSPH8,THOC1,KLF13,BCLAF1,SRSF5,SNRPD3,SAFB2,SLTM,DDX17,HNRNPA2B1,DHX16,CLK3,PPIG,RBMX,HNRNPH3,SAFB,PPIL2,TXLNA,ZNF326,RBM3,COPS7B,RBM12B,SNRNP70,RBM15,TRAF5 |
| 5.627e-06 | -12.09 | cytokinetic process | biological process | GO:0032506 | 20 | 12 | 17256 | 2622 |
PDCD6IP,RHOA,SNX18,KIF23,MYH9,RACGAP1,CNTROB,VPS4A,AURKB,ANLN,ANXA11,RTKN |
| 5.639e-06 | -12.09 | purine nucleoside triphosphate metabolic process | biological process | GO:0009144 | 225 | 60 | 17256 | 2622 |
GALK1,COX15,COX5B,NDUFA5,NDUFV2,NDUFS1,NDUFB6,UQCR10,MECP2,RAB23,OLA1,NDUFA4,COX4I1,CYCS,EFL1,ADPGK,ATP5F1B,ATP6V1B2,ATP5PF,SDHA,NDUFS7,NDUFS4,NDUFV1,NDUFA2,NDUFB4,MSH2,ATP6V0A2,NDUFB9,NDUFS8,CYC1,NDUFA3,TGFB1,RHOA,GUK1,LDHA,ATP6V0A1,OGDH,NDUFA7,NDUFB1,PKM,ATP5MF,TAZ,STOML2,HSPA1B,MBIP,ATP5MC3,PARG,COX7A2L,NDUFA11,COX8A,IMPDH1,COX5A,DHTKD1,UQCRH,NDUFS5,GPI,ATP5F1A,NIPSNAP2,PGAM1,PFKP |
| 5.656e-06 | -12.08 | GO_REGULATION_OF_SYMBIOSIS_ENCOMPASSING_MUTUALISM_THROUGH_PARASITISM | MSigDB lists | GO_REGULATION_OF_SYMBIOSIS_ENCOMPASSING_MUTUALISM_THROUGH_PARASITISM | 192 | 53 | 17377 | 2626 |
PPIB,CTDP1,CHMP2A,POLR2K,TRIM11,YTHDC2,TAP1,SMARCA4,EIF2AK4,CHD1,VPS25,GTF2F1,RAD23A,CCNK,TFAP4,SP100,ZNF639,BCL2,MDFIC,TAP2,TARDBP,MAVS,PABPC1,TRIM14,CFL1,SRPK2,STAU1,TRIM8,POLR2I,POLR2L,POLR2G,RAB7A,PPIE,ILF3,POLR2D,CHMP2B,TRIM28,ISG15,POLR2A,DERL1,TRIM26,POLR2J,STAT1,PML,CHMP4B,DDX5,TRIM32,RNASEL,VPS4A,PARP10,ZC3HAV1,IFI16,DDB1 |
| 5.656e-06 | -12.08 | GSE22886_NAIVE_CD4_TCELL_VS_12H_ACT_TH1_DN | MSigDB lists | GSE22886_NAIVE_CD4_TCELL_VS_12H_ACT_TH1_DN | 192 | 53 | 17377 | 2626 |
NDUFV2,SLC2A1,PLAGL2,CSNK2A1,RACGAP1,SLC25A44,CCNB1,TMEM165,POLR3K,RMI1,MRPL19,TFRC,SAC3D1,FASTKD3,C12orf10,IRF4,RBM23,PCNA,EIF2S2,PSMD1,ATP2A2,AHSA1,PPP1R8,PRC1,NUP153,STRAP,CSTF1,CCT2,ERCC1,RFC3,NSDHL,ERLIN1,WDR18,ACSL3,PSMA1,TBRG4,RANGAP1,BMS1,TMEM147,PICALM,CCT8,ABCF1,CHAF1A,SUPT16H,STOML2,SLCO4A1,PDCD6,PLAA,CCDC86,KHSRP,BAZ1B,PRPF4,TMEM33 |
| 5.656e-06 | -12.08 | GSE21670_TGFB_VS_TGFB_AND_IL6_TREATED_STAT3_KO_CD4_TCELL_DN | MSigDB lists | GSE21670_TGFB_VS_TGFB_AND_IL6_TREATED_STAT3_KO_CD4_TCELL_DN | 192 | 53 | 17377 | 2626 |
H2AFZ,ST13,KDM4A,MANBA,PDAP1,GPR89A,KIF23,CSNK2A1,RACGAP1,CSNK1A1,PSEN1,RBM4,FBXO3,ATP6V0B,RAP1A,PCNA,MED10,GOT2,DPYSL2,RABGAP1L,TTC9C,ARL6IP1,RNF19A,GTF2H2,STRAP,HTRA2,MYO5A,RPRD1A,AKT2,PSMB7,CYFIP2,SOX4,ARPC1A,RFC2,PSMB9,TTC33,PRIM1,POLE,CDC27,TWSG1,SPATA2,RBMX,CORO1C,E2F1,PTAR1,TRAF5,CD81,LONP2,HRAS,CAPN1,GPR89B,ALS2,FAM72A |
| 5.674e-06 | -12.08 | AAGWWRNYGGC_UNKNOWN | MSigDB lists | AAGWWRNYGGC_UNKNOWN | 113 | 36 | 17377 | 2626 |
UBE2D3,PIGN,CXXC1,STRN4,TIA1,ATG2B,ARF1,CNOT3,RAD23A,ANKRD28,CDKN2C,NUS1,SUV39H2,ZBTB22,RBM3,EIF5,RNF26,GNAI2,ANKHD1,RLIM,STAU1,NRAS,TRIM8,NASP,C16orf72,POLK,RAB22A,RHOB,POLR2A,SUPT16H,TSC1,PSMD8,CAMKMT,PREPL,YY1,ZC3HC1 |
| 5.732e-06 | -12.07 | Host Interactions of HIV factors | REACTOME pathways | R-HSA-162909 | 134 | 43 | 10287 | 1696 |
NDC1,NUP188,RAE1,RAC1,NUP54,ARF1,AP1B1,PSMD9,NUP205,HLA-A,PSMD2,PSMD1,NUP210,PSMA6,BANF1,NUP107,AP1M1,AP2B1,NUP153,NUP85,SEH1L,RBX1,PSMA8,PSMB7,PSMA1,NUP155,RANGAP1,PACS1,PSMB9,SLC25A5,PSMB3,PSMC4,KPNA1,RPS27A,ELMO1,PSMD8,PSMD3,AP1S1,NUP62,PSMC1,NUP58,AP2S1,AAAS |
| 5.777e-06 | -12.06 | MONTERO_THYROID_CANCER_POOR_SURVIVAL_UP | MSigDB lists | MONTERO_THYROID_CANCER_POOR_SURVIVAL_UP | 12 | 9 | 17377 | 2626 |
RRM2,NUSAP1,ANLN,UBE2C,BIRC5,CCNB2,ASPM,CEP55,PRC1 |
| 5.809e-06 | -12.06 | GSE18791_CTRL_VS_NEWCASTLE_VIRUS_DC_4H_UP | MSigDB lists | GSE18791_CTRL_VS_NEWCASTLE_VIRUS_DC_4H_UP | 173 | 49 | 17377 | 2626 |
SEPHS2,CCNC,NDUFA5,TP53RK,GXYLT1,URB2,GSPT2,MRPS26,SIKE1,PDCD7,IFT27,IL21R,METTL3,RMI1,GIT2,WRB,HMG20A,EDC3,MOAP1,FLAD1,ZNF302,CD3EAP,DNAAF2,TBC1D14,PHF14,RCSD1,MSH2,ANP32A,SLC35C2,TNRC18,TSHZ1,AGGF1,ZNF559,MBLAC2,MRPL12,THNSL1,CDC23,NDUFB1,GAR1,DDX23,PRIM1,RAD51C,HHEX,PALB2,RBL1,C1orf109,KBTBD7,SLC25A39,PDCD4 |
| 5.858e-06 | -12.05 | PUM3 (pumilio RNA binding family member 3) | protein interactions | 9933 | 123 | 40 | 17029 | 2761 |
NIFK,NOP2,RPL15,CTCF,EBNA1BP2,BRIX1,RBM4,APP,RPL23A,KRR1,DDX56,RBM34,NOC2L,RPF2,DDX31,FBL,ZC3H3,FTSJ3,NOL12,PPAN,STAU1,DDX24,AATF,GTPBP4,CUL3,RPL8,MAK16,DHX15,RPL36,NSA2,RPL32,DGCR8,TBL3,RPS14,RRS1,ZC3HAV1,IFI16,GPATCH4,DDX52,ZBTB24 |
| 5.874e-06 | -12.05 | POLD1 (DNA polymerase delta 1, catalytic subunit) | protein interactions | 5424 | 74 | 28 | 17029 | 2761 |
WASF2,TRIP10,POLK,DHX9,CUL3,CUL1,PTP4A3,DDX20,EIF2AK1,NCAPG,GAR1,GINS4,RPA1,XRCC5,WRNIP1,TERF2IP,RPA2,PCNA,UPF1,WDR44,MFAP1,ZNF746,UPF2,COPS6,CDK2,MCPH1,TERF2,CDC5L |
| 5.909e-06 | -12.04 | GROSS_HYPOXIA_VIA_ELK3_AND_HIF1A_DN | MSigDB lists | GROSS_HYPOXIA_VIA_ELK3_AND_HIF1A_DN | 100 | 33 | 17377 | 2626 |
SEPHS2,LZTR1,CDS2,AGRN,GADD45G,MOGS,MYH9,PLXNA1,CCNB1,WRB,SAC3D1,GART,SSBP3,AKAP8,RAD23B,TARDBP,F2R,LPCAT1,SRSF10,PRPF19,SIGMAR1,AMD1,RRM2,DIDO1,SRSF5,PLEC,MAT2A,FAS,SRSF1,ETS2,KPNA2,UBE2C,ZMAT3 |
| 5.909e-06 | -12.04 | MORF_TPT1 | MSigDB lists | MORF_TPT1 | 100 | 33 | 17377 | 2626 |
RPLP2,SUMO2,NACA,RPL15,RPL11,RPL23A,RPL17,YBX1,RBM3,RPL19,PABPC1,LYPLA2,PCBP2,CFL1,RPL29,RHOA,RPL38,RPL6,RPS10,RPL8,RPS24,EIF4G2,RPL27A,RPS9,RPL37,RPL32,RPS27A,RPS14,RPLP1,ACTB,BTF3,FAU,OAZ1 |
| 5.909e-06 | -12.04 | GO_SISTER_CHROMATID_COHESION | MSigDB lists | GO_SISTER_CHROMATID_COHESION | 100 | 33 | 17377 | 2626 |
MAPRE1,PHB2,CENPF,CDCA8,NUF2,KIF2C,PMF1,MIS12,RB1,SMC3,AHCTF1,NUP107,NAA50,PDS5B,KIF22,KNTC1,CENPM,MCMBP,NUP85,SEH1L,NUDC,PLK1,TAOK1,RANGAP1,AURKB,KIF2A,RAD51C,KIF18A,DSN1,BIRC5,CDCA5,CENPT,NDE1 |
| 5.938e-06 | -12.03 | Racgap1 (Rac GTPase-activating protein 1) | protein interactions | 26934 | 41 | 19 | 17029 | 2761 |
EIF5A,NRAS,POLR2G,MTA2,KIF23,RACGAP1,CCNL2,SHCBP1,FAM192A,SAFB,PPIL2,PRC1,TARDBP,COPS7B,RBM12B,FBXL19,ANXA11,MICAL3,FUBP1 |
| 5.942e-06 | -12.03 | RPN2 (ribophorin II) | protein interactions | 6185 | 98 | 34 | 17029 | 2761 |
COX15,TMBIM4,TM9SF4,TCF3,SDHA,CDC73,LIN9,GSTK1,RPN1,BABAM2,DAD1,ZNF746,SPTAN1,RHOA,MLEC,TACC1,RAB7A,CUL3,ILF3,ADRB2,VDAC1,MCM2,RAB1A,EPRS,ORMDL2,DDOST,H2AFX,NCLN,ATP5F1A,FUS,RBBP4,CLN3,ARRB2,FAF1 |
| 5.943e-06 | -12.03 | RBMX (RNA binding motif protein, X-linked) | protein interactions | 27316 | 149 | 46 | 17029 | 2761 |
CYLD,FOXM1,IVNS1ABP,TWNK,SF3B1,RAC1,RBM8A,CSNK2A1,SAFB2,PAIP1,SF3B2,EIF4A3,MCM5,AHSA1,ZNF746,NABP1,TRA2B,TARDBP,RBM3,HNRNPM,CDC5L,SRPK2,YTHDC1,GID8,STAU1,RB1CC1,SF3B6,HNRNPF,CUL3,CIRBP,SREK1,RRM2,MCM2,MATR3,SF3A2,SNRPA,DHX15,RPSA,CAND1,HNRNPR,CLK3,SAFB,RBMX,DDX5,FUS,SNRNP70 |
| 5.952e-06 | -12.03 | CDC37 (cell division cycle 37) | protein interactions | 11140 | 240 | 66 | 17029 | 2761 |
USP7,IMMT,CYLD,RPS6KA1,RAF1,CSNK2A1,UBE2I,PCBP1,APP,RAD23A,CDK5,ABL2,NEK6,TTC9C,EXOSC1,FNIP2,TTC4,AHCYL1,DCTN1,CDC37,DEAF1,ULK3,AURKB,BRCA1,OGFR,SLC25A5,DDX17,CLK3,SAFB,FTSJ1,STK11,PRPF4,FKBP5,DMWD,PPP5C,TUBB,EWSR1,RPS2,RAE1,PRKAA1,CDK13,DNAJB1,CDK11B,PSEN1,CEP104,FGFR3,AHSA1,PTGES3,MAP3K14,HNRNPM,LUC7L2,TERF2,RPAP3,EIF2AK1,PKM,CDK11A,PATL1,EVC2,UPF1,CDCA5,DDX5,BTBD10,PPP6R3,CDK2,MZT2B,TERF1 |
| 5.992e-06 | -12.03 | GSE6269_HEALTHY_VS_E_COLI_INF_PBMC_UP | MSigDB lists | GSE6269_HEALTHY_VS_E_COLI_INF_PBMC_UP | 159 | 46 | 17377 | 2626 |
MPHOSPH8,CXXC1,MECP2,MUM1,TOR3A,CDK2AP2,MOGS,ACAP1,CHKB,IRF3,EZH1,GGA2,DCUN1D4,SUPT7L,SAFB2,IL21R,METTL3,PDXDC1,ABHD14A,NRF1,AHSA1,SEC24C,PHTF1,PIGG,PDIA6,NUP85,MICAL3,HTRA2,MED22,CPNE1,HEMK1,MLEC,DCAF8,MRS2,SUGP2,NFATC2IP,ADRB2,ICMT,POLG2,AKAP1,SCAP,WDR59,LPCAT4,ZNF45,USP11,CSNK1D |
| 5.993e-06 | -12.02 | BTRC (beta-transducin repeat containing E3 ubiquitin protein ligase) | protein interactions | 8945 | 390 | 97 | 17029 | 2761 |
GGNBP2,HNRNPAB,SUZ12,PPP1R15B,MAGED1,PTTG1,HNRNPUL2,YTHDF3,CUL1,SIRT2,UBQLN2,CCNB1,PRKACA,MAPK14,CHD1,EEF2K,OIP5,DLG5,MDM2,CCDC50,MRPS27,NSFL1C,FBXW2,CRY2,MAST2,CDC25B,CCT2,CCDC138,AATF,RBX1,GOPC,BTG2,MRPL12,TUBGCP5,MCL1,WBP1,ERBIN,PRKRA,TAZ,DAP3,HINT1,E2F4,AXIN1,HIPK2,PPM1G,CEP55,OGT,CLU,DVL1,COPS6,SMURF1,SMAD4,PDCD4,UBE2D3,NCOR2,CLSPN,AGO2,CSNK1A1,CNOT11,FOXO3,TUBGCP2,NPLOC4,FBXO5,TFAP4,DCP1A,FOXN2,COPS7B,MRPL40,MRPL48,MRPL21,LPCAT1,NUDC,TXNL1,PRRC2A,TACC1,RPS10,KRAS,UBE4B,BORA,MTR,PRDX1,TWISTNB,CAND1,CNOT9,PFDN5,KEAP1,PCM1,PFDN4,E2F1,VCPIP1,YWHAZ,SNRNP70,PDLIM5,HRAS,TERF1,FAF1,DDB1 |
| 6.025e-06 | -12.02 | SSRP1 (structure specific recognition protein 1) | protein interactions | 6749 | 136 | 43 | 17029 | 2761 |
NOP2,SF3B1,SUMO2,CHD1L,DHX9,CUL1,CSNK2A1,JMJD6,THRAP3,CNTROB,ATP6V1B2,UBE2I,SDHA,CHD1,LMNA,CSDE1,RPA2,MCM5,SEC24C,TIMELESS,CTR9,ANP32A,FYTTD1,SREK1,RTF1,NFATC2,BRCA1,VDAC1,MCM2,RAB1A,POLR2A,GINS4,SUPT16H,CAND1,XRCC5,PAF1,NAP1L1,TONSL,H2AFX,HMGB2,WDR76,H3F3A,IFI16 |
| 6.034e-06 | -12.02 | Mdm2 (transformed mouse 3T3 cell double minute 2) | protein interactions | 17246 | 48 | 21 | 17029 | 2761 |
PLK1,CCT2,RPS2,SNRNP200,DDX24,RPS10,PIP4K2C,HNRNPF,EZR,THRAP3,RPS9,RPL11,XRCC5,PPP2CA,POLE,STK38,RPS14,HMGB2,CDK2,ARRB2,NUMB |
| 6.044e-06 | -12.02 | KPNA4 (karyopherin subunit alpha 4) | protein interactions | 3840 | 78 | 29 | 17029 | 2761 |
CCT2,UNK,IER2,PHF20L1,RECQL,MECP2,RAC1,CUL3,CTCF,CSNK2A1,DNAJA1,CCT8,APP,LMNA,MAT2B,CYHR1,PLAA,MTA1,AHSA1,ACLY,NUP107,CDKN1B,KPNA2,NUP153,KIF22,H3F3A,CFAP20,ARRB2,PARD3 |
| 6.052e-06 | -12.02 | GSE25087_FETAL_VS_ADULT_TCONV_UP | MSigDB lists | GSE25087_FETAL_VS_ADULT_TCONV_UP | 178 | 50 | 17377 | 2626 |
KARS,TRIP12,SUCLG1,DYNLL1,UQCR10,TCF3,GLUD1,SNRPD3,S1PR2,PIP4K2A,POFUT1,RGS1,NDUFS4,CCDC50,KLHL5,PTEN,INTS7,ATIC,LRRC59,TIPARP,MSH6,ABCC1,PTPRK,EIF5A,CCT2,TIMM8B,ORAI2,DENND1B,RRM2,KCTD20,ADSL,IL12RB1,NUTF2,CADM1,SOX4,SLC25A5,TARS,PRDX1,PSMC4,OSBPL11,TXNDC16,VPS26B,QARS,NEIL3,WDR4,STAT1,SLC16A1,NUP62,PRPF4,ZMIZ1 |
| 6.052e-06 | -12.02 | GSE12845_NAIVE_VS_DARKZONE_GC_TONSIL_BCELL_DN | MSigDB lists | GSE12845_NAIVE_VS_DARKZONE_GC_TONSIL_BCELL_DN | 178 | 50 | 17377 | 2626 |
RHOG,CMAS,SART1,RWDD1,UGP2,MRPS2,DAP,UBXN1,LAGE3,KIF2C,TMEM165,REEP5,RBM4,KIFC1,ANKRD26,CD59,GSTK1,DDX56,NAPG,DNAJC8,PDCD10,ATIC,PIN1,ANP32A,KIFAP3,CYC1,UBE3C,ORC3,TPCN1,HNRNPM,PREB,SPTAN1,CLCN3,NASP,RBM42,PSPC1,MRPL16,FAM50B,MEN1,ICMT,COMMD4,PDHX,NECAP2,DDX23,DTWD1,PSMD8,RBMX,HPS5,MDH1,PSMC1 |
| 6.052e-06 | -12.02 | GSE17974_CTRL_VS_ACT_IL4_AND_ANTI_IL12_12H_CD4_TCELL_DN | MSigDB lists | GSE17974_CTRL_VS_ACT_IL4_AND_ANTI_IL12_12H_CD4_TCELL_DN | 178 | 50 | 17377 | 2626 |
WSB2,INTS2,SRM,PIGM,GNPNAT1,CDK2AP2,UCK2,MRPS26,KLHL18,SNRPD3,BLM,BRIX1,TCF19,TMEM165,FANCI,PNO1,LYAR,SNRNP25,HOMER1,RAP1A,CLIC4,SLC38A5,GOT2,MCM5,BDH1,POP7,SPTSSA,FTSJ3,MLEC,TMEM126B,SCFD2,PSMG1,VDAC1,GAR1,FADD,SLC19A1,KEAP1,ORMDL2,C1orf109,BAZ1B,SSNA1,SMG9,RUVBL2,RRS1,NANP,PDCD2L,AAAS,RAD51D,TUBB,BYSL |
| 6.074e-06 | -12.01 | GO_CARBOHYDRATE_DERIVATIVE_METABOLIC_PROCESS | MSigDB lists | GO_CARBOHYDRATE_DERIVATIVE_METABOLIC_PROCESS | 980 | 198 | 17377 | 2626 |
COX15,PIGM,PPCS,GXYLT1,NDUFB6,AGRN,GNPDA1,PRKCSH,UQCR10,PIGQ,HEXB,MOGS,SIRT2,NANS,CREM,MBD4,TET3,IMPAD1,PPCDC,AKR1B1,UPRT,NDUFB9,SLC26A2,SLC35C2,TIPARP,DNMT1,MGAT5,OGG1,ABCC5,PGAP2,TMEM115,DPM1,MKI67,RRM2,AMDHD2,GALNT7,MCFD2,ICMT,ARF4,STOML2,ALG3,MAN2A2,STT3A,NAGLU,OGT,MLYCD,DHTKD1,COX5A,UQCRH,ST3GAL2,GALNT10,CLN3,NGLY1,CHPF2,PFKP,B4GALT2,COX5B,NDUFV2,PIGN,GORASP1,SDC2,RRM1,CERK,B4GALT1,ASAH1,NDUFA4,COX4I1,CYCS,B4GALT4,PSEN1,TMEM165,NDUFS7,NDUFS4,GNS,RPN1,C1GALT1,NUS1,DAD1,ATIC,PIGG,MSH2,ATP6V0A2,GLTP,AHCY,CYC1,NAGPA,PIGT,TSTA3,MAN1B1,AMD1,GBA,DCTD,SYVN1,MPG,ADSS,GALNT2,GOLGA2,UAP1,DCK,PRPS2,COX7A2L,TYW5,LPCAT4,TBPL1,CTSA,GPI,SMPD4,NANP,HEXA,PTDSS1,NDUFA5,DNMT3A,UGP2,GNPNAT1,UCK2,OLA1,UCK1,ADPGK,SLC35B2,ATP6V1B2,EXT2,DUT,ADCY9,RPN2,TALDO1,LMAN1,AHCYL1,GPD1L,CLN6,GM2A,PDCL3,ADCY7,ENPP4,ATP6V0A1,PFKFB3,NDUFA7,OGDH,EDEM2,NDUFB1,TAZ,SERP1,MAT2A,DDOST,HINT1,NDUFA11,CANT1,MBOAT1,B4GALT3,CHID1,GALK1,CMAS,NDUFS1,B4GALT5,MECP2,MRI1,GNE,TRAK1,TKT,SUMF1,ABHD14B,SDF2L1,POFUT1,NEIL2,MAN1A1,MAT2B,ERH,NDUFV1,GART,NDUFA2,ITGB8,NDUFB4,FUT8,NDUFS8,OSTC,ST8SIA2,NDUFA3,TGFB1,B3GALT6,AMPD2,TK1,GUK1,GALC,PARP4,LDHA,ADSL,PDE3B,ARSK,NEU1,HSPA1B,SGSH,MAGT1,CTBS,COX8A,IMPDH1,NDUFS5,PSAP,PARP10,PGAM1 |
| 6.075e-06 | -12.01 | VANOEVELEN_MYOGENESIS_SIN3A_TARGETS | MSigDB lists | VANOEVELEN_MYOGENESIS_SIN3A_TARGETS | 207 | 56 | 17377 | 2626 |
CTU2,CMAS,PKP4,MZT1,URB2,RAE1,TRMT6,OLA1,PMS2,PPP3CB,SLC12A9,USP5,WWP2,TERF2IP,GNS,DTL,ANKRD26,VMP1,CD3EAP,POP7,ANXA5,SUCLG2,AHCY,PIK3IP1,NAP1L4,CREB1,RHBDD2,ZNF189,HP1BP3,ABCC5,FTL,CLCN3,ERF,NOA1,COQ10B,IDH3A,RAD51AP1,NLN,RPS24,DCTD,GFER,RPS9,RPSA,GEMIN5,DAP3,C1orf131,PARG,HIPK2,ERGIC3,NRM,NFIL3,APPL2,PPP1R11,MLYCD,NMD3,RNF114 |
| 6.100e-06 | -12.01 | protein targeting to membrane | biological process | GO:0006612 | 149 | 44 | 17256 | 2622 |
RPS15,RPS2,RPLP2,RPL15,ATG4A,SSR1,RPL23A,RPL11,RPL17,ATG3,ARL6IP1,RPL19,SRP72,ZDHHC18,RPL29,SEC61B,RPL35,RPL6,RPL8,RPL38,RPS10,SSR2,RPS24,RAB3IP,ICMT,RPL27A,ZDHHC3,RPS9,RPSA,RPL36,RPL37,PEX5,CHMP4A,RPL32,SEC61A1,GOLGA7,RPS27A,RPS14,RPLP1,EXOC4,ZDHHC7,CHMP4B,RPS26,PARD3 |
| 6.104e-06 | -12.01 | HMGXB4 (HMG-box containing 4) | protein interactions | 10042 | 28 | 15 | 17029 | 2761 |
SYNCRIP,RABGAP1L,UROD,HABP4,PML,ARAP1,DNAJC24,JMJD6,KIF22,KIFAP3,CNTROB,RBBP4,SMARCE1,EPM2A,SRPK2 |
| 6.123e-06 | -12.00 | mitotic DNA damage checkpoint | biological process | GO:0044773 | 104 | 34 | 17256 | 2622 |
CLSPN,CCNB1,BLM,CNOT11,FANCI,CNOT3,RPA2,RFWD3,MDM2,PCNA,CENPJ,MSH2,CDKN1B,GTSE1,CNOT6L,ATF2,CARM1,PLK3,BTG2,PRKDC,TAOK1,MRNIP,SOX4,CNOT9,RPS27A,E2F4,TFDP1,PML,E2F1,CNOT6,CHEK2,ZNF830,TFDP2,CDK2 |
| 6.158e-06 | -12.00 | GO_ENDOPLASMIC_RETICULUM_PART | MSigDB lists | GO_ENDOPLASMIC_RETICULUM_PART | 1090 | 217 | 17377 | 2626 |
TMED7,PIGM,PDCD6IP,COPA,TMEM203,ADAM10,PRKCSH,PIGQ,TAP1,TMEM109,MOGS,AGPAT1,FKBP2,IKBIP,CDIPT,SEC16A,BECN1,RNF103,SSR1,DST,NUP210,CDC42,CYB5RL,RAB35,TTC9C,SRI,ZFYVE27,CISD2,MARCH2,TECR,SPTSSA,LRRC59,PGAP2,DPM1,APH1A,ATG9A,SUMF2,PITPNB,ESYT1,MCFD2,ICMT,KRTCAP2,RAB2B,RHEB,ALG3,AGPAT2,STT3A,TMED10,MIA2,PIEZO1,CLN3,RTN3,SVIP,PPIB,PIGN,AGTRAP,SEC61G,HLA-E,UBXN1,TMED3,RAB6A,SLC35B1,NOTCH2,PSEN1,COPG2,RHBDD1,COPB2,NPLOC4,DDRGK1,CD59,FKBP1A,RNF121,RPN1,NUS1,LRRC8D,DAD1,ARL6IP1,PIGG,EI24,SLC27A4,BCL2,PCYT2,LPCAT1,TMED2,KDELR1,PREB,FDFT1,EIF5A,PIGT,SIGMAR1,ERLIN1,NSDHL,MAN1B1,ACSL3,RDH10,SSR2,SYVN1,VKORC1,CYB5A,RDH11,SEC31A,DERL1,MOSPD3,GALNT2,ORMDL2,TXNDC16,ERGIC3,LPCAT4,SIL1,SAMD8,SMPD4,MAP3K5,PTDSS1,RNF139,APOL2,TMEM106C,RHOG,ATXN3,CHERP,COPE,RAC1,VTI1A,SLC35B2,LCLAT1,EXT2,BCAP31,KTN1,SEC11A,RAB21,ATP2A2,LPIN2,ANKRD13C,BCAP29,TAP2,RPN2,CYB5R1,MINPP1,AHCYL1,LMAN1,PDIA6,CLN6,HTRA2,ACSL5,ANKLE2,UBQLN4,ERMP1,ATP13A1,SEC61B,TOR1AIP2,DNAJA1,PKMYT1,TMEM147,EDEM2,RAB1A,SERP1,FKBP3,RHBDF2,DNAJC10,SEC61A1,DDOST,SURF4,SCAP,CERS6,SEL1L,CANT1,NCLN,ATF6,FKBP5,MBOAT1,REEP4,ABCA1,TMEM33,CDS2,TOR3A,TMX3,AGPAT3,SUMF1,SDF2L1,WRB,HLA-A,DNAJB9,SPPL2A,EBP,CAPN2,SEC24C,RRBP1,SLC35B4,OSTC,CNPY3,PACS2,TMX1,RNF5,CAMK2G,ELOVL5,RHOA,MLEC,PNPLA8,ARSK,SPPL2B,YIF1A,HLA-B,RAB18,PLD3,PDCD6,MAGT1,OSBPL8,WNT5B,STX18,DBI,PML,PGRMC1,PKD2,ASNA1,SPCS3,PLOD3,FAF1,ESYT2 |
| 6.178e-06 | -11.99 | GO_MITOCHONDRIAL_RESPIRATORY_CHAIN_COMPLEX_I_BIOGENESIS | MSigDB lists | GO_MITOCHONDRIAL_RESPIRATORY_CHAIN_COMPLEX_I_BIOGENESIS | 51 | 21 | 17377 | 2626 |
NDUFA5,NDUFV2,NDUFS1,NDUFB6,TIMMDC1,NDUFAF2,TMEM126B,NDUFA7,NDUFB1,TAZ,FOXRED1,NDUFS7,NDUFS4,NDUFV1,NDUFA2,NDUFB4,NDUFA11,NDUFB9,NDUFS8,NDUFS5,NDUFA3 |
| 6.178e-06 | -11.99 | GO_NADH_DEHYDROGENASE_COMPLEX_ASSEMBLY | MSigDB lists | GO_NADH_DEHYDROGENASE_COMPLEX_ASSEMBLY | 51 | 21 | 17377 | 2626 |
NDUFA5,NDUFV2,NDUFS1,NDUFB6,TIMMDC1,NDUFAF2,TMEM126B,NDUFA7,NDUFB1,TAZ,FOXRED1,NDUFS7,NDUFS4,NDUFV1,NDUFA2,NDUFB4,NDUFA11,NDUFB9,NDUFS8,NDUFS5,NDUFA3 |
| 6.178e-06 | -11.99 | GO_MITOCHONDRIAL_RESPIRATORY_CHAIN_COMPLEX_I_ASSEMBLY | MSigDB lists | GO_MITOCHONDRIAL_RESPIRATORY_CHAIN_COMPLEX_I_ASSEMBLY | 51 | 21 | 17377 | 2626 |
NDUFA5,NDUFV2,NDUFS1,NDUFB6,TIMMDC1,NDUFAF2,TMEM126B,NDUFA7,NDUFB1,TAZ,FOXRED1,NDUFS7,NDUFS4,NDUFV1,NDUFA2,NDUFB4,NDUFA11,NDUFB9,NDUFS8,NDUFS5,NDUFA3 |
| 6.253e-06 | -11.98 | VANTVEER_BREAST_CANCER_METASTASIS_DN | MSigDB lists | VANTVEER_BREAST_CANCER_METASTASIS_DN | 109 | 35 | 17377 | 2626 |
SKA3,HJURP,DEPDC1,IVNS1ABP,CENPF,MCCC1,AGFG1,STMN1,QSOX2,TFRC,KIAA1147,FBXO5,DTL,PSMD2,INTS7,UCHL5,KIF14,PRC1,CDC25B,LPCAT1,SMC4,MAPRE2,TK1,ASPM,NUSAP1,SYNCRIP,ATAD2,BIRC5,DCK,MRPL13,PITRM1,CCNB2,PTDSS1,PFKP,NIPA1 |
| 6.272e-06 | -11.98 | V$E2F1DP1RB_01 | MSigDB lists | V$E2F1DP1RB_01 | 217 | 58 | 17377 | 2626 |
POLA2,H2AFZ,CLSPN,ZCCHC8,RAB11B,CDT1,TRMT6,RMI2,SMC6,CTCF,STMN1,ASXL2,FBXO5,TFAP4,PCNA,SMC3,INTS7,CD3EAP,DPYSL2,PPP1R8,PPIG,FIZ1,MSH2,PCYT2,MCMBP,ANKHD1,DNMT1,ARID4A,SP3,YTHDC1,ZNF524,NASP,APH1A,ILF3,DNAJC9,RRM2,CDC6,NFATC2IP,PKMYT1,MCM2,MAT2A,POLR2A,SRSF1,HMGN2,CAND1,ATAD2,HNRNPR,DCK,LUC7L3,ZNF367,MAPK6,KBTBD7,E2F1,NUP62,RBPJ,WDR62,SASS6,GEN1 |
| 6.276e-06 | -11.98 | GSE22033_UNTREATED_VS_ROSIGLITAZONE_TREATED_MEF_UP | MSigDB lists | GSE22033_UNTREATED_VS_ROSIGLITAZONE_TREATED_MEF_UP | 183 | 51 | 17377 | 2626 |
CMAS,NACA,OLA1,TMEM109,RRM1,GTF3A,RAB11A,GIT2,STAM,SSR1,PCYOX1L,PDK2,DUS4L,COQ4,GOT2,CENPJ,LPIN2,XPA,FAM89B,NSFL1C,EFCAB11,TIMELESS,COPS7B,CORO1A,ALDH18A1,SLC35A1,HTRA2,TMED2,HNRNPM,ADCY7,PRPF19,NOL12,MOB4,LARS,TK1,CSRP1,SIGMAR1,HNRNPF,KRAS,VDAC1,PRIM1,DTWD1,TIMM17A,NEIL3,ARNTL,FN3KRP,MRFAP1L1,SNRPG,RUVBL2,SMG9,CCNB2 |
| 6.276e-06 | -11.98 | GSE22601_CD4_SINGLE_POSITIVE_VS_CD8_SINGLE_POSITIVE_THYMOCYTE_UP | MSigDB lists | GSE22601_CD4_SINGLE_POSITIVE_VS_CD8_SINGLE_POSITIVE_THYMOCYTE_UP | 183 | 51 | 17377 | 2626 |
MIF4GD,HJURP,WDYHV1,DAP,KIF23,PTP4A3,GTF3A,SLC29A1,LANCL1,TAF6L,FKBP2,REPS1,FANCI,LMNA,CD320,MBD4,KIFC1,HERC3,PCNA,EFCAB11,GTSE1,GEMIN6,ZBTB22,AHCY,ANAPC7,RNASEH2A,PRADC1,FDFT1,CDC5L,MAPRE2,MAPKAPK3,WDHD1,NFATC2IP,PRKRA,C9orf40,RHOB,AMZ2,CDC27,PTER,NEIL3,ERGIC3,CDCA7L,MYO18A,PQBP1,KHSRP,ANP32E,KPNA2,NANP,BRD9,RTN3,PDCD4 |
| 6.286e-06 | -11.98 | Synthesis of DNA | REACTOME pathways | R-HSA-69239 | 101 | 35 | 10287 | 1696 |
POLA2,CDT1,ORC1,PSMD9,RPA2,RB1,PSMD2,PCNA,PSMD1,PSMA6,CCNA2,MCM5,CDKN1B,ORC3,GINS1,RFC3,PRIM2,PSMA8,PSMB7,PSMA1,CDC6,MCM2,PSMB9,RFC2,GINS4,PSMB3,PRIM1,RPA1,PSMC4,POLE,RPS27A,PSMD3,PSMD8,CDK2,PSMC1 |
| 6.319e-06 | -11.97 | GSE11973_MIR223_KOVS_WT_BONE_MARROW_NEUTROPHIL_DN | MSigDB lists | GSE11973_MIR223_KOVS_WT_BONE_MARROW_NEUTROPHIL_DN | 164 | 47 | 17377 | 2626 |
DDX58,UNK,RRP15,B4GALT5,NUP54,CYCS,FKBP2,LYN,RAPGEF6,BCAT2,RPN1,UTP18,DDA1,ZDHHC13,MRPL54,PARL,ECD,PTGES3,TMEM136,LMAN1,MRPL21,STAT3,COPS8,AATF,NUDT4,RPL38,TBRG4,WDR82,GORASP2,BMS1,RAB3IP,PSMB9,PICALM,CCT8,RHBDF2,ALG3,GRIPAP1,TIMM17A,PPA2,PML,SIAH2,PTAR1,PPP3R1,FTSJ1,IMPDH1,PPP5C,SLC25A33 |
| 6.330e-06 | -11.97 | GO_REGULATION_OF_VACUOLE_ORGANIZATION | MSigDB lists | GO_REGULATION_OF_VACUOLE_ORGANIZATION | 40 | 18 | 17377 | 2626 |
TBC1D12,UBQLN4,FEZ2,PHF23,RAB7A,PIP4K2C,ADRB2,UBQLN2,PIP4K2A,SH3GLB1,MTMR3,CHMP4A,RALB,TBC1D14,CHMP4B,PIKFYVE,LRSAM1,RNF5 |
| 6.356e-06 | -11.97 | MCAATNNNNNGCG_UNKNOWN | MSigDB lists | MCAATNNNNNGCG_UNKNOWN | 79 | 28 | 17377 | 2626 |
LONRF3,ADAM10,SRSF6,CDK2AP2,DCTN2,AMD1,CDCA3,RMI2,ARGLU1,CYCS,ZFAND5,STMN1,USP5,CHKA,HMGN2,RAB8A,RAD51C,VASP,ATP2A2,DGCR8,RNF38,ARL6IP1,ATE1,CNN2,PRADC1,ATF2,ABI1,TMED2 |
| 6.397e-06 | -11.96 | Nucleotide-bd_a/b_plait_sf | interpro domains | IPR012677 | 244 | 63 | 18492 | 2768 |
NIFK,EWSR1,HNRNPAB,R3HCC1L,SRSF6,RBM8A,TIA1,SAFB2,PARN,MYEF2,RBM4,PABPC4,RPL23A,RAVER2,HNRNPA2B1,RBM17,RBM23,GRSF1,RBM34,SRSF4,TRA2B,TARDBP,RBM3,RBM12B,RBM15,PABPC1,HNRNPM,SRSF10,RBM15B,SRSF11,RBM42,PSPC1,NOL8,SF3B6,PPIE,HNRNPF,RNPS1,CIRBP,SREK1,SRSF5,EIF4H,EIF3G,SLTM,MATR3,SNRPA,RBM38,SRSF1,RBM25,RBM47,SYNCRIP,HNRNPR,HNRNPH3,SAFB,RBMX,U2SURP,DNAJC17,RBMS1,SRSF3,FUS,SNRNP70,HNRNPDL,PARP10,CPEB2 |
| 6.400e-06 | -11.96 | GSE6259_FLT3L_INDUCED_DEC205_POS_DC_VS_CD4_TCELL_UP | MSigDB lists | GSE6259_FLT3L_INDUCED_DEC205_POS_DC_VS_CD4_TCELL_UP | 150 | 44 | 17377 | 2626 |
URB2,DYNLL1,PHRF1,TOR3A,STARD7,CDC42SE2,MAPK14,EIF1B,SEC16A,LCLAT1,EXT2,FARSA,MED10,GMEB1,AP1M1,ABCD1,PPA1,MED22,B3GALT6,MOB4,PPP3CA,TMEM39A,NSDHL,ZMYND11,ILF3,TUFM,RABIF,AZI2,PTTG1IP,TOLLIP,RAB22A,USP21,TWISTNB,TMEM184C,VEZF1,HHEX,GOLGA4,PTAR1,PPP6R2,EHD4,PTDSS1,BYSL,FAF1,CWC25 |
| 6.400e-06 | -11.96 | GSE7348_UNSTIM_VS_TOLERIZED_AND_LPS_STIM_MACROPHAGE_UP | MSigDB lists | GSE7348_UNSTIM_VS_TOLERIZED_AND_LPS_STIM_MACROPHAGE_UP | 150 | 44 | 17377 | 2626 |
TCF12,TBC1D12,NCOR2,GNE,CERK,FAM76A,TIA1,MEF2A,EIF2AK4,PDCD7,SNAPC4,RMI1,HMG20A,STARD9,AHCTF1,KLF16,KIF13B,ADCY9,PPCDC,NAP1L4,RBM15,CNNM3,FTSJ3,PREB,B3GALT6,DEAF1,TMEM115,KLF10,EHMT1,TLK1,HNRNPF,NARF,WDR81,USP36,SLCO4A1,TRIM47,PDCD6,ACYP1,GPS2,DGCR8,ARNTL,USP20,MBD6,NUMB |
| 6.441e-06 | -11.95 | BAG6 (BCL2 associated athanogene 6) | protein interactions | 7917 | 288 | 76 | 17029 | 2761 |
IMMT,TOMM20,NOP2,TRIP10,UBR2,CAST,TRIM11,MAGED1,PTTG1,RAC1,FKBP2,PRNP,CDK5,FANCL,APLP2,RAB8A,PIN1,MTA1,RPAP1,MAVS,KCNAB2,RLIM,PLK1,UBQLN4,SEC61B,WDHD1,EIF3H,DOT1L,MAP3K4,KIF2A,SEC61A1,MRPL55,CEP55,CLU,PDCD11,C2CD5,PDF,USP13,EWSR1,SRGN,UBXN1,CERK,SDC2,HLA-A,WWP2,RB1,RPN1,HUWE1,YBX1,MYDGF,RNF5,EEF1D,TK1,TRAFD1,PRIM2,RFXANK,UHRF1BP1,SYVN1,PNPLA8,PRMT2,MACF1,MAPK3,FAS,CTSL,POLR2J,UAP1,MAPK6,CDCA5,USP32,ASNA1,TCOF1,WDR91,HEXA,FAF1,CDKN2A,IPO4 |
| 6.442e-06 | -11.95 | MSN (moesin) | protein interactions | 4478 | 132 | 42 | 17029 | 2761 |
HSPH1,EWSR1,PPP1R2,TKT,MYH9,NOTCH2,FKBP2,CDK11B,CDC73,BCAP31,CAPN2,DUT,ATIC,NSFL1C,AKR1B1,AHCY,TAGLN2,IMPA2,SPTAN1,RHOA,SELPLG,WDR1,MRPL12,EZR,BRCA1,PLEC,ICAM2,MCM2,DHX15,FADD,ISG15,FAS,HLA-B,TSC1,HSPA4,H2AFX,ROCK1,TATDN1,CDK2,SMURF1,CD81,TERF1 |
| 6.475e-06 | -11.95 | kidney-other-neoplasm | COSMIC cancer mutations | kidney-other-neoplasm | 10949 | 1728 | 17385 | 2587 |
HECA,ZBTB10,HEXB,LACTB2,CCNL2,ANKRD39,ZNF275,FBXO22,CDKN2C,NAPG,THAP4,RAD23B,ATP13A3,MECR,AP1M1,DNM2,UPRT,LRRC59,TIPARP,MGAT5,FTSJ3,USP34,BAK1,CCDC57,RHOBTB3,EHMT1,KIF15,WDHD1,MIER2,NUTF2,DIDO1,WBP1,RAB22A,ARF4,KRIT1,AHNAK,SMAD2,RAD18,PDRG1,MPV17,COX5A,RNASEL,SMAD1,ANXA11,PDCD4,SLC25A33,ZNF720,NXT2,HIVEP3,CLSPN,KIAA0100,SEC61G,GGA1,MUM1,TRIO,DHX9,RAB23,EIF2AK4,PDCD7,APH1B,PSMD9,PARN,CDC73,HAUS2,MYL6B,COPB2,TMEM179B,TFAP4,CD59,SMC3,RIMS3,EFTUD2,FBXO7,MRPL21,MVP,NUP85,PABPC1,NSUN4,PPA1,LUC7L2,EIF3L,IFRD1,AGGF1,FOXK1,RBM42,TYW1,GTPBP4,SSR2,ITM2A,USP10,MRPL16,EIF4H,SFXN5,RDH11,FNTA,KPNA1,TXNDC16,PDLIM1,ETS2,TYW5,WIPI2,PDLIM5,ACSF2,MRPL3,ALS2,RHOG,EXOC3,TRIM41,NQO1,POC1A,PTTG1,ANK3,VTI1A,TPX2,TBC1D13,INO80E,RCOR3,LCLAT1,GLRX3,CPNE3,KIAA1147,ABHD16A,ZNF420,AHCTF1,TBC1D22A,SH3BP1,MTA1,TBC1D14,UBA5,NSFL1C,CLCN6,SEPT11,INTS12,GPD1L,ZC3H3,RPRD1B,PDCL3,SNX8,CPNE1,SEC61B,ERMP1,FAM118B,GOPC,IDH3A,CRNKL1,RPL38,E2F3,PFKFB3,MEF2D,TANC1,RAB1A,MAT2A,PPP2CA,VPS26B,CCDC14,NSMCE2,CORO1C,CAMKMT,RNF38,DMWD,SNRPG,PPP5C,PITRM1,TUBB,USP13,COMMD10,MZT1,ZFP91,HABP4,TRMT6,CCM2,FLOT1,BTN3A1,ATG2B,WDR5,PMVK,SLC25A43,NEIL2,SRXN1,GOLM1,RPA2,PSMD2,PDCD10,CLIC4,ITGB8,COQ4,CBWD2,ARF5,ARHGEF1,NAA50,ANXA5,LTN1,UBE3B,NAP1L4,ZNF710,ST8SIA2,GTF2H2,STAU1,TCTEX1D2,DDX24,TACC1,MRS2,LDHA,LLPH,RAB3IP,TTC33,PICALM,UTP20,SH3BP5,SLC19A1,ACOX1,FAM3C,CD81,PARP10,YWHAH,TMEM131,WDR13,TRIM11,FAM129A,YTHDC2,SNX15,NENF,SND1,RUFY1,TRIM65,PAPOLA,ZER1,PRNP,CREM,KRR1,FANCL,TET3,RAB8A,NUP210,NT5DC1,INTS1,IL6ST,SLC44A1,NOC2L,EIF5,MTPN,ASB6,TACC3,VPS13B,RYBP,PTPN18,CELSR2,MIOS,RBX1,MBLAC2,PSMG1,CKAP2L,PBRM1,EAF2,ODC1,USP21,LSG1,ALG3,TRIM4,TRAM2,FBXO28,AGPAT2,CHD3,ZNF367,ADAM9,PRPF4,DVL1,CLN3,BEND6,FAM208A,NGLY1,POT1,NUMB,ZNF564,RMND5A,PARP12,HJURP,FAM53C,CENPF,NKD2,LAMTOR3,SDC2,KLC1,COX4I1,ADCK5,CDK13,NCKAP1,RSAD1,TNS3,C1GALT1,UBE2Q2,CCP110,KIF13B,MBD2,ZNF746,ARL6IP1,CTR9,AHCY,GLE1,LRSAM1,HDHD2,NIPSNAP1,NTPCR,ABHD2,DCAF8,NSDHL,ACSL3,AMD1,CAMSAP1,MAP4K3,METTL22,ICAM2,STYXL1,APPL1,RBM38,IRF5,NMT2,HAUS8,RXRB,SDHB,MBIP,PCM1,GALNT2,TMEM168,COX7A2L,NLRC5,SIL1,DTD1,BTBD10,MYO9A,CCNB2,UNC13C,USP7,SART1,GLT8D1,TRAF7,SUCLG1,ARID2,NDUFAF2,TMX4,TOR1AIP1,SLC2A1,ZFYVE21,TM9SF3,RRAGC,ATP6V1B2,LYN,VAV1,OIP5,MRPL50,NRF1,PSMA6,ZNF473,BRPF3,WDR44,PPME1,EFCAB11,RPAP1,TARDBP,BCAP29,CABLES2,TOP1MT,AHCYL1,LMAN1,STRAP,CTDSP2,ZNF583,SPSB3,PRPF19,SNX25,PPIF,KDM3B,MND1,CLCN3,POLR2G,ZNF780B,RAB7A,ANKRD33B,PPIE,NUP155,DCLRE1C,CHMP2B,VDAC1,MRPS14,EIF3H,RHBDF2,TMEM201,GLOD4,SUGP1,IDE,RBL1,STK38,UBXN2B,FASTK,UHRF2,AP1S1,CHMP4B,XRCC3,SMAD4,PARD3,SLC30A9,NADSYN1,CMAS,KLHL21,PDAP1,CDCA8,TMX3,GTF3A,NCAPG,SCYL2,TUBGCP2,FZD6,HERC3,HOMER1,CTSS,WBP1L,POLR1B,ORC3,RNLS,YTHDC1,PPAN,RPRD1A,CSRP1,BTAF1,TUFM,TOP3A,ARHGEF12,RANGAP1,PNPLA8,ZFR,DDX23,RAB18,ATP6V1D,SEC23IP,L3MBTL3,NEIL3,CTBS,BBX,IMPDH1,TMEM219,TAF12,NR2F2,HIPK3,IFI16,NUP188,TXN,MAX,PDCD6IP,LUZP1,GXYLT1,PRKCSH,ADAM10,TSC22D3,AP3M2,CUL1,USP39,NANS,GYG1,OAT,MYEF2,SLC25A37,ANKRD26,NOL11,FIZ1,RAB4A,TRA2B,CISD2,SLC26A2,ZNF800,CDC5L,SRP72,OSBP2,KLF10,NSUN2,USP22,RFC2,EIF3A,PRIM1,ZMYM3,IWS1,ANKRD10,HHEX,RPS14,TPP2,LUC7L3,MAP4,BTF3,PTPDC1,ZMAT3,NMD3,PTOV1,RECQL,C9orf78,EWSR1,SCOC,POLR2K,C16orf87,PRKAA1,ANKH,RRM1,DLGAP4,ACAP1,TATDN3,B4GALT1,PXMP2,FAM136A,ZNF79,PSEN1,TMEM165,PDXDC1,NPLOC4,YY1AP1,WDR48,SPAG5,RTKN,C12orf10,FAM192A,RPN1,CEP104,EXOSC7,LHX8,KLHL5,ARPC5,ZNRF2,LRRC8D,MSH2,DAPK1,PIGG,TPST1,OSTF1,FBXL7,FAM171A1,SYTL3,APOL1,FDFT1,GCC2,PIGT,PRIM2,ELL2,EMB,RDH10,MFNG,GORASP2,EXOSC9,ARID1A,CAPZA2,FXR1,PTTG1IP,GOSR1,MAP2K2,CCT8,MTR,TWISTNB,PHF6,AKAP1,PI4K2A,XRCC5,DERL1,CAT,SLCO4A1,HSPBP1,TTC13,GOLGA2,RBMX,MED15,USP32,FAM83D,APPL2,ARAP1,CABIN1,SAMD8,SMPD4,GPI,NUDT3,CYTIP,ATXN3,RAB11B,KIAA0232,BCL2L1,C2orf49,EPM2A,DECR1,MTMR4,RALB,LPIN2,ADCY9,MRPS27,BRI3,TTC3,TP53BP2,RNASEH2A,AQR,RBM12B,ILKAP,CDK12,ANKLE2,BRD4,CDC123,OAF,DRAP1,NARF,LRRC8A,ELP4,ASB13,ERC1,SUPT16H,AMZ2,ANKZF1,ZNF282,CHMP4A,DDOST,DSN1,DGCR8,SAFB,LMBR1,RWDD4,CBWD1,ATF6,NCLN,BEND3,EYA2,DYNC1LI2,ADAM23,NDUFS1,SLC41A1,B4GALT5,MECP2,MANBA,TKT,CBLL1,ARGLU1,SECISBP2,LANCL1,POFUT1,HMG20A,FAM8A1,HEATR5B,WWP2,SLC25A36,RFWD3,DNAJC8,NDUFA2,FUT8,AXIN2,PTPN11,BTF3L4,MRPL54,FEM1B,MTX2,MSH6,JMJD4,KAT2A,LONRF3,RABIF,FBXO9,PACS1,BMS1,KCNQ1,OTUD3,ARSK,KIF11,KLF6,GUF1,MACF1,SMAP2,FADD,MYO1F,TMEM127,RPL32,ZHX1,OAZ2,DDX5,WDR62,WDR91,ESPL1,DDB1,DEF6,FAM83G,IPO4,POLA2,UBL3,ZNF76,LYRM4,GPR132,COPA,UQCR10,HMGXB3,PHRF1,UBE2Q1,PTP4A3,ABCB10,BRIX1,MRPL19,PCYOX1L,DST,SYNM,GOT2,RAB35,JAZF1,HADHB,RPF2,GPATCH1,CNNM3,CARM1,SRPK2,WDR41,LARS,DEAF1,ZCCHC10,SNRNP200,CCDC138,NCK1,LAP3,VHL,LRBA,KMT2C,OGFR,PRPSAP1,ASF1B,RPL37,MAN2A2,HSPB11,EIF4ENIF1,BRWD1,PPM1G,U2SURP,MIA2,BAZ1B,ZNF268,CHEK2,CLU,VPS4A,ZSWIM3,MRPL13,CHPT1,ATP6V0E1,DCAF5,CAPN1,UBE2D3,PPP1R2,PPP1R12A,EPN1,THRAP3,PM20D2,XPNPEP3,RGS2,TTF1,QSOX2,PRPF18,NUP205,CHKA,LYAR,DTL,MED10,ZRANB1,SLC12A2,ATP6V0D1,CSNK1G3,TRAFD1,NUDT4,SUGP2,GBA,EIF2A,SYVN1,SLTM,ARHGAP15,EVC2,MASTL,UAP1,KLHL15,SIAH2,FN3KRP,YWHAZ,SNRNP70,EHD4,TMEM14A,APOL2,TSEN15,N4BP2L2,ADNP2,TCF12,PRKAB1,FEZ2,CORO7,MDH2,PMS2,UCK2,SMARCA4,ORC1,MXD1,HNRNPA2B1,RRN3,UBXN2A,IARS,NVL,KIF14,EXOSC1,CS,CLTB,ZNF770,DNAL4,EBAG9,CSTF1,POU2AF1,UBQLN4,PGGT1B,SMU1,PCGF6,ATXN1,GLO1,OGDH,BICD2,CADM1,HERPUD2,EDEM2,TOLLIP,MBD3,PDHX,RPS9,PON2,SURF4,HNRNPR,STAT6,HPS5,ARNTL,ANP32E,FKBP5,CCDC125,MAPK1,ABCA1,PDCD2L,TMEM33,DNAJC2,GCLM,TRIP12,RAE1,SCYL1,DCTN2,NUP54,VPS45,CHIC2,PAWR,MYO9B,DCUN1D4,PIP4K2A,GFM2,XPR1,SPPL2A,KIF5B,FASTKD3,FGFR3,KLHL20,SEC24C,PPIG,RRBP1,TMEM99,H2AFY,ANP32A,NDUFS8,LDLRAD3,FBL,ERI3,C12orf75,STAT3,FRMD8,SLC35A1,MYO5A,MICAL3,NIPAL3,TGFB1,TXNL1,DCAF6,FAM49B,TIMMDC1,TMEM39A,PSPC1,HELB,SCFD2,RFFL,COG1,RCOR1,PRMT2,NDRG3,CDK11A,LEMD2,UPF1,ELMO1,ZC3H7B,DTX4,ACAT1,MEGF9,ZMIZ1,PLOD3,RAB3IL1,ZSWIM6,CCDC93,TMED7,ADD1,MRPS15,KDM4A,PIGQ,XIAP,DHX8,GLUD1,CNTROB,PPP1R16B,ANKRD23,PABPC4,CDK5,PSMD1,NSRP1,RABGAP1L,TTC9C,SRSF4,PDS5B,NUP153,PCBP2,KCNAB2,PLK3,PGAP2,ZNF672,TMEM115,PLEKHM3,SMC2,DCUN1D5,PPFIA3,ICMT,PWWP2B,WDR11,AXIN1,LIMK1,PRDX5,MLYCD,ATP6V0C,ST3GAL2,FBXL3,E2F2,LONP2,PFKP,AAAS,DDX42,SSRP1,NDUFV2,PHF23,MRPS2,STRN4,CERK,TOP2B,SLC4A2,TMED3,EZH1,ITGB5,LMNA,MCTS1,RAVER2,DDRGK1,GNS,DDX56,EIF2S2,SLC38A5,INTS7,MCM5,PHF14,ZNF326,FOXN2,UBE2QL1,CARS2,NAGPA,PRRC2A,RB1CC1,C16orf72,ZMYND11,PGS1,DHX29,MAN1B1,TEX10,MYBL2,UHRF1BP1,CBFA2T2,MPG,ABCF1,MATR3,CYB5A,LRRC14B,PTPRF,DTWD1,SCARB2,OSBPL11,CCDC86,DUSP3,SETD3,CNOT6,NDE1,HEXA,SNX14,EGLN1,ANKRD27,PPP1R37,ABCA3,SARNP,TRERF1,IVNS1ABP,UBR2,ACTR3,CHD1L,WDTC1,MYH9,CREBL2,NIT2,ZNF267,PRKACA,SAFB2,TMEM161B,APP,ANKIB1,STAM,ARL6IP6,RAB21,CLUAP1,PRKD3,ATP2A2,SP100,ZKSCAN1,UTP18,ZCCHC2,DDA1,NUP107,ANKRD13C,RNF19A,CEP63,MAVS,FAM76B,CLN6,ATF2,TMEM9,RNF169,ADCY7,ATP6V1G1,SHOC2,PSRC1,MAP4K4,RNPS1,CDCA2,NUSAP1,NDUFA7,DNAJA1,DDX17,CHCHD3,PEX5,CDC16,SEC61A1,HIPK2,WDR7,CBLN2,MBOAT1,PDXK,COIL,LRP8,LRCH1,ANXA6,TMBIM4,SESTD1,TRAK1,SIKE1,GMCL1,AKT1S1,UBE4A,WRB,ZNF92,KRI1,CAPN2,FBXO3,ERH,ADD3,GATC,NDUFB4,PRDM4,GEMIN6,GTSE1,DCP1A,TTLL12,SGCB,IMPA2,HNRNPM,MFSD12,LDHB,PDPK1,PPP3CA,TK1,TNFAIP3,GALC,ZNF512,KIAA0930,MRPS10,MTMR12,ZP3,PDE3B,RPA1,ZNF180,ZNF862,KIF18A,KEAP1,POLE,CCDC6,TATDN2,MAPK6,CAPN7,PML,LRPPRC,LY75,SLC25A19,RGL1,PSAP,WDR76,USF2,IGBP1,FAF1,ANAPC4,COX15,AGRN,THOC1,GNPDA1,GPBP1L1,PPP1R15B,MCCC1,CSNK2A1,CDC42SE2,SEC16A,GIT2,BIRC2,ATPAF1,SSR1,LIN9,DLG5,TRMU,PIK3R2,ETV6,PPCDC,TXLNA,ZFYVE27,MYBL1,MCMBP,MRPL32,CCAR1,PTPRK,CDC37,ABCC5,METTL1,HARS,MRPL12,GMFB,LNX2,EZR,LRP5,ESYT1,PRKRA,ANLN,STX16,RHEB,OPTN,DPYSL3,SEPT1,TONSL,NRM,NAGLU,QRSL1,ACTB,PIEZO1,OSGEPL1,NUDT11,GLCCI1,NAA60,LZTR1,CTCF,ASAH1,RACGAP1,PPP3CB,B4GALT4,DOCK11,RLF,CRLF3,RAPGEF6,NUS1,VASP,VMP1,TIMELESS,SLC27A4,AHDC1,MDFIC,MAML1,ALDH18A1,ABCC1,TRAPPC9,AACS,NQO2,MEMO1,UTP15,EIF2AK1,UBE4B,LY6E,ARPC1A,EIF4G2,ZDHHC3,ZNF174,MOSPD3,GOLGA4,ITPRIPL1,SYNCRIP,PALB2,SNAP23,PRPS2,PRMT7,NIPA1,RNF114,CYLD,UGP2,FOXM1,XAB2,MRPL39,SUMO2,COPE,GGPS1,DUSP22,RAD23A,RPL11,CSDE1,ATP6V0B,MDM2,STRBP,DUS4L,PDCD2,MINPP1,METTL9,SAP30L,DVL2,POC5,GM2A,SLC39A9,CLPTM1,PSMA8,CPOX,CYP20A1,SLC26A6,MTMR6,NFATC2,PRPF3,KDM1B,TXNL4A,CCDC127,DNAJC10,ATP1A1,SCAP,ZNF700,PSMD3,CEP55,DNAJC17,NCOA1,LTA4H,USP53,ZC3HC1,ATXN7L2,INTS2,CTDP1,CDC40,GOLIM4,RRP15,DAP,CDT1,ARID5A,SMC6,SUMF1,GGA2,AP3S1,BZW2,TFRC,WRNIP1,PTPN2,STARD9,NDUFV1,SLC1A4,CWC27,SLC35B4,ABCD1,DDX31,PTGES3,CAMK2G,RPAP3,SNX2,ZMYM5,PPWD1,RHOT2,CHCHD6,BSDC1,NEU1,TPD52L2,KPNA4,GOLGA7,TWSG1,SNAP29,TFE3,CDCA7L,GLG1,FAM126A,PKD2,RPS6KC1,UBE2C,GCSH,ZNF496,PPCS,NDUFB6,TMEM41B,ZDHHC8,YTHDF3,NHLRC3,PLXNA1,IKBIP,SLC20A1,COMMD6,ABHD14A,ELMOD2,POLR3K,KIFC1,ASAP2,SNUPN,CYB5RL,PARPBP,CNPY4,PRADC1,PLCL2,DNMT1,SEH1L,ORAI2,AKT2,NOL8,GNG7,MKI67,DDX20,GALNT7,SLC17A5,CCNF,FOXRED1,ZFAND5,SLC25A5,TMED10,PTER,PSMD8,WDR4,EIF2D,ITGB1,DHTKD1,UQCRH,TRAF5,RTN3,ZNF598,DDX58,WSB2,PPIB,HSPH1,MAPRE1,MUT,KIF23,NOTCH2,PMF1,MAN2B1,METTL3,NDUFS4,CFLAR,FKBP1A,RNF121,KLF16,DAD1,HDAC7,BDH1,ATP6V0A2,PIKFYVE,RNF135,GNAI2,LPCAT1,ANKHD1,TMED2,EEF1D,TERF2,MORC3,FTL,PIP4K2C,KCTD20,DCTD,FAM133B,RIT1,PKM,KDM3A,PATL1,ADSS,EPRS,ZNF777,TMEM54,ZFP92,NSF,DCK,ERGIC3,ACLY,VCPIP1,TCOF1,YY1,PPP6R2,MAP3K5,RNF14,CABLES1,NRBP1,ZC3HAV1,DNMT3A,CKLF,RWDD1,TRIP10,URB2,CAST,SUZ12,RPS6KA1,SF3B1,MAGED1,GPR89A,EIF3D,OLA1,KLHL18,ADPGK,AP1B1,SLC25A44,SDHA,PAIP2,PHC2,CRKL,TERF2IP,APLP2,ZNF75D,KDM2A,UCHL5,CDKN1B,TALDO1,NAA35,MAPRE2,MKLN1,CUL3,SLBP,CDC23,AP4E1,SHCBP1,PSMB9,POLG2,DHX57,PRDM11,VEZF1,HSPA4,PPP2R5A,JAK1,TBL3,PPA2,SEL1L,STAT1,KLHDC4,B4GALT3,PDCD11,POLQ,OTUD5,PKP4,C1orf112,BABAM1,MRI1,TCF3,BRAP,SLC25A12,AGPAT3,BLM,FOXO3,REEP5,RAB11A,CCDC28A,MAD2L2,TMCC3,GTF2F1,MAT2B,RBM17,PTEN,CRAT,AHSA1,CENPJ,PRC1,UPF2,IFT46,PACS2,NCOA2,SMC4,ZFP64,NET1,NEK7,DENND4C,PARP4,ILF3,ANAPC2,LRRC1,RHOT1,ECH1,PRDX1,FBXO21,GNA12,NUCB1,SGSH,HGS,C1orf131,PFDN4,PRDX3,MFAP1,TFDP1,STX18,KHSRP,CCDC69,BRWD3,BYSL,S100PBP,ESYT2,MIB2,PTMS,UBE2E2,SKA3,NPHP4,ST13,TMEM184B,HNRNPAB,PLXNC1,NF1,DCAF15,ALKBH5,DNAJC24,ZNF107,UBE2Z,TAF6L,SIRT2,SLC29A1,KIF2C,USP48,SNRPD3,MAPK14,BECN1,SNAPC4,RNF103,EDC3,BCAT2,UBLCP1,ZNF804A,RAP1A,EIF4A3,THADA,AP3S2,METTL14,DPYSL2,ATG3,ZNHIT6,IMPAD1,RCSD1,PHTF1,PPP1R12C,AKR1B1,KIF22,JOSD1,RP2,NFU1,TTC4,TECR,ARID4A,TRIM14,TIMM50,COPS8,FYTTD1,TDP1,TRIM8,DPM1,FOPNL,SLC16A7,SLC25A22,STK17B,DHX15,ABHD5,CHAF1A,CXXC4,GEMIN5,PAF1,IARS2,ATXN2L,GALNT10,SASS6,STARD3NL,SLC12A7,TBC1D12,PIGN,AGTRAP,CIB1,TIA1,MED13L,EPHX2,SRRT,RHBDD1,ZNF449,ZNF335,BUD31,CAPZA1,YBX1,BCL2,KIFAP3,GLTP,KNTC1,ACAD8,UBE3C,N4BP2,KDELR1,HP1BP3,ZNF189,VOPP1,CIC,OXR1,SEPT7,CAND1,TSC1,NAP1L1,RBM25,ODF2,EXOC4,KIAA1328,PITPNA,ZFP90,NAA20,RBBP4,PDSS2,PTDSS1,C7orf26,ZBTB24,SMARCD1,MBD1,WASF2,TOMM20,ASH1L,IMMT,IFI27L1,GNPNAT1,MPHOSPH8,CHERP,WDYHV1,HNRNPUL2,PLAGL2,CHKB,CHD1,PAIP1,C2orf68,FARSA,CCDC50,PARL,RPN2,SCAMP4,APOOL,PDIA6,F2R,FAM3A,TMEM14C,ABI1,ACSL5,FAM172A,PSMB7,NLN,WIPF1,TOR1AIP2,AZI2,BUD13,PEF1,BTBD1,RAD54B,DAP3,TMEM41A,TAB2,TULP3,WDR59,SCARB1,GAS2,AKNA,SMURF1,REEP4,TSPAN5,CBX4,KIF3B,CDS2,GOLPH3L,SH2D3A,CASP6,EYA1,TOR3A,SRGN,KLF13,LETMD1,HDDC2,MAN1A1,SAC3D1,GART,CTNNBL1,TANK,BRD7,TTC17,SAMD4B,GINS1,ZDHHC18,TELO2,CSNK1G2,ADAM17,NASP,ASPM,PPP1R21,PRKAR1B,POLR3GL,MEN1,ZNF407,SYMPK,TARS,SNRPA,MFN2,ATAD2,PLAA,ZNF330,OSBPL8,SRSF3,PREPL,TATDN1,ATP6V1C1 |
| 6.481e-06 | -11.95 | GSE41176_UNSTIM_VS_ANTI_IGM_STIM_BCELL_24H_DN | MSigDB lists | GSE41176_UNSTIM_VS_ANTI_IGM_STIM_BCELL_24H_DN | 188 | 52 | 17377 | 2626 |
WASF2,HIVEP3,GGNBP2,FAM53C,GADD45G,SLC2A1,TMX4,PTTG1,ARID5A,CDC42SE2,USP48,PDCD7,MAPK14,STMN1,LMNA,CENPJ,RRBP1,ZNF326,AFF1,ANAPC7,TP53BP2,MCMBP,CGGBP1,RYBP,KLF10,ERF,BAZ2A,ACSL3,WDHD1,TOPORS,ARID1A,PRPSAP1,APPL1,BTBD1,RHOB,IRF5,RBM38,PHF6,CAND1,ABHD5,DOT1L,PPP2CA,HLA-B,KPNA1,KLHL15,H2AFX,PGRMC1,E2F1,ATP6V0E1,CBX4,DEF6,FAM83G |
| 6.481e-06 | -11.95 | GSE1432_CTRL_VS_IFNG_6H_MICROGLIA_UP | MSigDB lists | GSE1432_CTRL_VS_IFNG_6H_MICROGLIA_UP | 188 | 52 | 17377 | 2626 |
RMND5A,CCDC93,CYTIP,CDK2AP2,LAGE3,CTCF,USP39,TBC1D13,GMCL1,EZH1,SUPT7L,ASXL2,SYNRG,CUTC,MRPL19,SAC3D1,ZER1,CDK5,SNRNP25,RBM23,NDUFA2,LRRC8D,MCM5,SIVA1,SSBP3,BDH1,PHTF1,MSH2,PARL,TTC3,NFU1,CNNM3,OGG1,SPSB3,LUC7L2,ABCC5,TRIM8,MRS2,SLC26A6,JTB,ATP6V0A1,UBE4B,GALNT7,ASB13,RPA1,ANKRD10,FBXO21,GOLGA8A,SEL1L,STK11,ZMAT3,ATMIN |
| 6.481e-06 | -11.95 | GSE1432_1H_VS_6H_IFNG_MICROGLIA_DN | MSigDB lists | GSE1432_1H_VS_6H_IFNG_MICROGLIA_DN | 188 | 52 | 17377 | 2626 |
SLC12A7,USP7,ANKRD27,KARS,CYLD,MAX,PARP12,HLA-E,TAP1,LAMTOR3,TIA1,CUL1,PRPF39,GGPS1,SCYL2,RAD23A,RALB,ATG3,RBM34,SRI,TARDBP,MVP,MOB1A,STAT3,SAP30L,CDKN2AIP,USO1,RHOBTB3,BIRC3,LAP3,DENND1B,AMD1,USP10,PRPF3,DNAJA1,PSMB9,RHBDF2,FNTA,MTHFD2,KEAP1,CERS6,DUSP3,STK38,PRPS2,STAT1,RBMS1,NUP62,RGL1,RRS1,SMURF1,APOL2,RNF114 |
| 6.481e-06 | -11.95 | GSE26030_TH1_VS_TH17_RESTIMULATED_DAY15_POST_POLARIZATION_UP | MSigDB lists | GSE26030_TH1_VS_TH17_RESTIMULATED_DAY15_POST_POLARIZATION_UP | 188 | 52 | 17377 | 2626 |
TMEM106C,MCM10,PLXNC1,HJURP,PRKCSH,ZBTB37,TPX2,RRM1,CDCA8,FLOT1,STMN1,TCF19,VAV1,UBXN2A,CCNA2,BRPF3,LRRC8D,LPIN2,PPP6C,TPST1,PRC1,PARL,CENPM,METTL9,CNPY3,IMPA2,CAMK2G,PLK1,MAPRE2,PRIM2,SELPLG,RAD51AP1,MKI67,RRM2,EDEM2,H2AFV,ASF1B,PRIM1,HSPB11,POLE,DSN1,TTLL4,BIRC5,SNAP23,ZNF367,ARAP1,FAM83D,C4orf46,HMGB2,CDK2,LTA4H,SVIP |
| 6.481e-06 | -11.95 | GSE1925_CTRL_VS_IFNG_PRIMED_MACROPHAGE_UP | MSigDB lists | GSE1925_CTRL_VS_IFNG_PRIMED_MACROPHAGE_UP | 188 | 52 | 17377 | 2626 |
PTMS,AGTRAP,XIAP,BRAP,KIF2C,SLC29A1,BCL2L1,REPS1,SRXN1,SUV39H2,TBC1D22A,HDAC7,MCM5,ARF5,NUP107,AP1M1,TIMELESS,SUCLG2,AFF1,RNF26,NUP85,PTPRK,SRPK2,PPIF,RPL35,ACP2,MKLN1,C16orf72,IDH3A,MKI67,ATXN1,PITPNB,RAB3IP,CCNF,NDRG3,USP21,MTR,ALG3,HHEX,GNA12,SURF4,ETS2,E2F1,CANT1,PKD2,CLU,YY1,PPP6R3,NDE1,LTA4H,TUBB,ZC3HC1 |
| 6.528e-06 | -11.94 | GO_VACUOLAR_MEMBRANE | MSigDB lists | GO_VACUOLAR_MEMBRANE | 553 | 122 | 17377 | 2626 |
RAB14,SNX27,CHMP2A,GNPNAT1,RAB11B,ABCC10,RAC1,VTI1A,RRAGC,AP1B1,ATP6V1B2,MAP1LC3B,BECN1,RUFY1,STAM,GNB2,CD320,PCYOX1L,RAB21,NAPG,ATP6V0B,RAB8A,SHC1,WDR44,MTMR4,RAB35,CLCN6,AP1M1,AP2B1,ZFYVE27,RPN2,MARCH2,TMEM9,TMBIM1,DRAM2,ATP6V1G1,WDR41,SNX25,SNX8,CLCN3,MIOS,ATG9A,GOPC,RAB7A,ATP6V0A1,SLC17A5,CHMP2B,RAB5B,RAB22A,RHEB,PLEKHF2,AHNAK,CHMP4A,WDR11,TAB2,RPS27A,AP1S1,ATP6V0C,TICAM1,CHMP4B,SCARB1,VPS4A,CLN3,AP2S1,ATP6V0E1,STARD3NL,UBE2D3,DNAJC5,GOLIM4,ANXA6,GGA1,HLA-E,CCZ1,VPS45,RAB23,FLOT1,LAMTOR3,ACAP1,GGA2,PSEN1,TMEM165,RAB11A,VPS25,SCYL2,TFRC,HLA-A,SPPL2A,VMP1,ZNRF2,SNX18,ATP6V0A2,TMEM8A,PIKFYVE,ATP6V0D1,TPCN1,ACP2,SNX2,GBA,RFFL,SPPL2B,APPL1,RHOB,SH3GLB1,NEU1,PI4K2A,HLA-B,SCARB2,HGS,OSBPL11,ATP6V1D,NSF,SNAP29,CCZ1B,PML,APPL2,CTSA,PSAP,EHD4,ATP6V1C1,CHMP7,SNX14,VPS29 |
| 6.538e-06 | -11.94 | organellar large ribosomal subunit | cellular component | GO:0000315 | 52 | 21 | 18223 | 2701 |
MRPL9,MRPL42,MRPL39,MRPL43,MRPL12,MRPL16,MRPL19,MRPL50,MRPL2,MRPL55,MRPL27,MRPL34,MRPL54,MRPL48,MRPL40,MRPL11,MRPL21,MRPL13,NSUN4,MRPL3,MRPL32 |
| 6.538e-06 | -11.94 | mitochondrial large ribosomal subunit | cellular component | GO:0005762 | 52 | 21 | 18223 | 2701 |
MRPL9,MRPL42,MRPL39,MRPL43,MRPL12,MRPL16,MRPL19,MRPL50,MRPL2,MRPL55,MRPL27,MRPL34,MRPL54,MRPL48,MRPL40,MRPL11,MRPL21,MRPL13,NSUN4,MRPL3,MRPL32 |
| 6.539e-06 | -11.94 | fibrillar center | cellular component | GO:0001650 | 134 | 40 | 18223 | 2701 |
KDM4A,RAE1,MRI1,IP6K2,UBE2I,CHD1,RPAIN,YY1AP1,CD3EAP,JAZF1,FBL,MAP3K14,UTP4,CDK12,EEF1D,EIF3L,DEAF1,USO1,PSPC1,UTP15,EZR,SUPT20H,KLF6,GAR1,UBTF,TIMM13,DSN1,SPATA2,CHCHD1,CDCA7L,PRMT7,DUSP11,TCOF1,MBD6,RRS1,BTBD10,AKNA,TERF1,COIL,CCDC137 |
| 6.626e-06 | -11.92 | positive regulation of cell cycle | biological process | GO:0045787 | 379 | 90 | 17256 | 2622 |
CCNC,UBE2E2,THOC1,KMT2E,POC1A,CCNL2,SIRT2,CCNB1,PRKACA,BECN1,APP,RAD23A,PCNA,MDM2,CDC42,KIF14,CDKN1B,CDC25B,CARM1,SRPK2,PLK3,PSRC1,BRD4,PGGT1B,BTG2,CUL3,CDC6,NUSAP1,LRP5,USP22,AURKB,BRCA1,SOX4,PAF1,RAD51C,RPS27A,NSMCE2,E2F4,UHRF2,XRCC3,ZNF268,CHEK2,TRIM32,TFDP2,GEN1,SLF1,MIF,KIF3B,PKP4,PHB2,MECP2,CDT1,KIF23,RACGAP1,CRLF3,PAGR1,CNOT11,RAB11A,CDC73,CNOT3,SPAG5,DDRGK1,CCNK,TFAP4,DTL,RB1,CENPJ,PTPN11,GTSE1,H2AFY,CITED2,CNOT6L,TGFB1,ADAM17,RHOA,HMGN5,CNOT9,DUSP3,TFDP1,CDCA5,PML,FAM83D,E2F1,NUP62,CNOT6,PKD2,UBE2C,CDK2,ESPL1,SLF2 |
| 6.654e-06 | -11.92 | regulation of DNA repair | biological process | GO:0006282 | 100 | 33 | 17256 | 2622 |
TRIP12,FOXM1,EYA1,BABAM1,DHX9,TERF2IP,RPA2,PCNA,CYREN,BABAM2,TIGAR,PARPBP,AXIN2,TIMELESS,SPIDR,OGG1,RNF169,TERF2,HELB,RAD51AP1,MRNIP,UBE2V1,BRCA1,TRIM28,PARG,KLHL15,PML,CEBPG,H2AFX,SLF1,SLF2,EYA2,POLQ |
| 6.667e-06 | -11.92 | GSE43260_BTLA_POS_VS_NEG_INTRATUMORAL_CD8_TCELL_UP | MSigDB lists | GSE43260_BTLA_POS_VS_NEG_INTRATUMORAL_CD8_TCELL_UP | 193 | 53 | 17377 | 2626 |
KCTD7,PPIB,GCLM,MAPRE1,EWSR1,GMFG,NQO1,GNPDA1,TMEM41B,KLC1,JMJD6,FKBP2,BCAP31,HDDC2,LMNA,SPAG5,CNOT3,MOAP1,RPN1,UTP18,ADCY9,RRBP1,TXLNA,DNM2,YBX1,PDIA6,ATP6V0D1,PPIF,SEC61B,GUK1,RBM42,ERF,GABPA,DRAP1,TLK1,HTATIP2,PITPNB,MCFD2,SEC31A,NUCB1,KEAP1,UAP1,GOLGA2,PSMD8,TIMM17A,ATXN2L,PITPNA,ATP6V0C,SRSF3,RBBP4,HEXA,HRAS,PTOV1 |
| 6.667e-06 | -11.92 | GSE22886_NAIVE_VS_MEMORY_TCELL_DN | MSigDB lists | GSE22886_NAIVE_VS_MEMORY_TCELL_DN | 193 | 53 | 17377 | 2626 |
HECA,PKP4,PPP1R2,IVNS1ABP,SUMO2,SNX15,CBLL1,CREBL2,PRPF39,KCMF1,GTPBP3,RAP1A,MEX3C,RAD23B,PPP6C,FOXN2,MDFIC,TAGLN2,PTGES3,TP53BP2,CITED2,CDC5L,EIF5A,ELOVL5,SEPT9,BIRC3,PBXIP1,EID1,KIAA0040,HNRNPF,LDHA,PSMA1,HEBP2,USP10,ICAM2,EIF4G2,CBFB,MATR3,ZFR,ARHGAP15,GLOD4,SEC31A,GOLGA7,TAB2,RBL1,PGRMC1,CAB39,YWHAZ,WDR76,EHD4,REEP4,TSPAN5,N4BP2L2 |
| 6.673e-06 | -11.92 | CD81 (CD81 molecule) | protein interactions | 975 | 199 | 57 | 17029 | 2761 |
RPS15,IMMT,RPS2,EWSR1,RPLP2,UBXN1,SNRPD3,PCBP1,LMNA,RPL11,RPL23A,HNRNPA2B1,DLG5,SHC1,RPL17,MCM5,CNN2,PDIA6,PABPC1,PCBP2,CFL1,LUC7L2,EEF1D,HNRNPM,EIF3L,RPL35,SNRPB,RPL6,TUFM,RTF1,ADRB2,PKM,VKORC1,RPL27A,RPS9,EIF3G,DHX15,EIF3A,EIF3H,SUPT16H,DDX17,EIF3K,SYNCRIP,RPS14,ITGB1,KHSRP,DDX5,ACTB,ATP5F1A,SRSF3,FAU,RBBP4,CD81,PFKP,TUBB,PDCD4,FUBP1 |
| 6.686e-06 | -11.92 | SCLT1 (sodium channel and clathrin linker 1) | protein interactions | 132320 | 154 | 47 | 17029 | 2761 |
EXOC3,GALK1,FGFR1OP,LUZP1,RAB11B,RPS6KA1,PRKAA1,DCTN2,C19orf25,NUP54,KIF23,SIRT2,IFT27,COMMD6,COMMD8,MYEF2,CPNE3,HLA-A,CALM2,SHC1,ARHGEF2,TP53BP2,CHTOP,PREB,STAU1,MLEC,CCDC138,RCOR1,RRM2,KRTCAP2,COMMD4,ERC1,GLOD4,NECAP2,UPF1,EIF4ENIF1,PCM1,HSPA4,HINT1,NSF,PFDN4,CCDC14,TPP2,EXOC4,NIPSNAP2,NUP58,SNAPIN |
| 6.686e-06 | -11.92 | NDUFS3 (NADH:ubiquinone oxidoreductase core subunit S3) | protein interactions | 4722 | 154 | 47 | 17029 | 2761 |
NDUFA5,COX15,NDUFV2,IMMT,NDUFS1,NDUFB6,UBR2,UQCR10,CHCHD2,NDUFA4,ATP5PF,SDHA,PARK7,NDUFS7,NPLOC4,NDUFS4,NDUFV1,NDUFA2,NDUFB4,HUWE1,ZNF746,NDUFB9,NDUFS8,CYC1,NDUFA3,TMEM14C,HTRA2,NIPSNAP1,PTPN18,TIMMDC1,COQ8A,TMEM126B,CUL3,MRPS10,MRPL16,NDUFA7,ADRB2,VDAC1,NDUFB1,ECH1,STOML2,NDUFA11,SLC16A1,NDUFS5,PITRM1,MRPL13,MRPL3 |
| 6.706e-06 | -11.91 | DEBIASI_APOPTOSIS_BY_REOVIRUS_INFECTION_UP | MSigDB lists | DEBIASI_APOPTOSIS_BY_REOVIRUS_INFECTION_UP | 303 | 75 | 17377 | 2626 |
FGFR1OP,ATXN3,NF1,TAP1,AGFG1,CREM,KRR1,RAB21,SP100,SOCS6,TIPARP,RYBP,SHOC2,NRAS,MKLN1,PGGT1B,RAD51AP1,TLK1,MCL1,BRCA1,PITPNB,OGFR,PSMB9,STK17B,MAK16,FBXO28,CLK3,LSM6,TIMM17A,STAT1,RBMS1,ATF6,RRS1,SMNDC1,PRPF4B,DNAJC2,PRKAA1,DHX9,MED13L,BRAP,PAWR,SIKE1,PPP3CB,ZNF518A,RLF,DNAJB9,PNO1,PTPN2,CCP110,ZNF189,RBM15B,GINS1,YTHDC1,MOB4,IFRD1,TNFAIP3,NEK7,OTUD3,CAPZA2,FXR1,KLF6,ISG15,TWISTNB,CDC27,PFDN4,DUSP3,CCDC6,ZNF330,CEBPG,PML,TBPL1,PGAM1,IFI16,ZC3HAV1,RNF114 |
| 6.706e-06 | -11.91 | MODULE_72 | MSigDB lists | MODULE_72 | 303 | 75 | 17377 | 2626 |
IMMT,TSC2,SUZ12,PTTG1,TMX4,TPX2,CSNK2A1,SMARCA4,KIF2C,GYG1,SAFB2,STMN1,BIRC2,PAIP1,CREM,PCNA,UTP18,INTS1,DNM2,CYB5R1,DNMT1,PLK1,SP3,SGCE,TLK1,PSMG1,MTMR6,SLBP,PKMYT1,CADM1,MCM2,PRPSAP1,TRAM2,DAP3,GOLGA8A,DDX42,PTOV1,EWSR1,MAPRE1,TRIP12,DNAJB2,UBXN1,KCTD17,DHX9,UBE4A,TMED3,RAB11A,MYL6B,WRB,TFRC,HDDC2,SAC3D1,SMC3,CCP110,SEC24C,PPP4R1,PCYT2,UBE2M,ATP6V0D1,GCC2,ABHD2,TSPYL4,RANGAP1,SRSF5,HAGH,DDX39A,SF3A2,CBX3,NSF,MAPK6,TFDP1,OAZ2,RBBP4,CCNB2,MRPL3 |
| 6.747e-06 | -11.91 | REACTOME_APOPTOSIS | MSigDB lists | REACTOME_APOPTOSIS | 141 | 42 | 17377 | 2626 |
ADD1,CASP6,DYNLL1,MAGED1,XIAP,CYCS,BCL2L1,PSMD9,BIRC2,BCAP31,LMNA,CFLAR,PSMD2,PSMD1,PSMA6,DAPK1,BCL2,SPTAN1,BAK1,PSMA8,PSMB7,PSMA1,PLEC,PSMB9,APPL1,PSMB3,DAPK3,FADD,PSMC4,FAS,KPNA1,FNTA,RPS27A,PSMD8,PSMD3,TFDP1,PPP3R1,E2F1,HMGB2,ROCK1,GAS2,PSMC1 |
| 6.765e-06 | -11.90 | PPP2CA (protein phosphatase 2 catalytic subunit alpha) | protein interactions | 5515 | 274 | 73 | 17029 | 2761 |
USP7,FGFR1OP,TSC2,RAF1,RAC1,PMS2,ENSA,MYH9,CUL1,CDKN2C,PSMD1,PIN1,PPME1,INTS1,INTS12,AHCYL1,FGFR1OP2,ANKLE2,CCT2,AKT2,VHL,CUL3,AURKB,BRCA1,PPFIA3,TRIM28,CLNS1A,CDCA4,PPP2R5A,AXIN1,PSMD3,CHEK2,PTPDC1,MAPK1,SMURF1,PPP2R2D,INTS2,UNK,CTDP1,PRKAA1,MRPS26,STRN4,SIKE1,CSNK1A1,RPA2,PDCD10,HDAC7,PPP4R1,DAPK1,ARHGEF2,TNPO3,BCL2,PABPC1,MOB4,STRIP1,PRKDC,PACS1,CCT8,TTC33,RHOB,MAPK3,RPA1,PCM1,ATP6V1D,CDC27,GOLGA2,CCDC6,KLHL15,FAM122A,CDK2,IGBP1,TERF1,ESPL1 |
| 6.855e-06 | -11.89 | RPGRIP1L (RPGRIP1 like) | protein interactions | 23322 | 163 | 49 | 17029 | 2761 |
CEP170B,TRIM41,NPHP4,DDX47,PPP1R12A,LUZP1,DYNLL1,RAF1,KIF23,RACGAP1,SIRT2,RAB6A,SDHA,TFRC,SPAG5,ABRACL,ANKRD28,DDX56,SMC3,CCP110,NDUFB4,KIF14,CAPZA1,CTPS1,MSH2,GPATCH1,TP53BP2,CHTOP,RBM15,N4BP2,DVL2,MOB4,CCDC138,ERLIN1,ELOA,NUP155,CAPZA2,RAB5B,ABCF1,ECH1,HAUS8,KIF2A,UPF1,EIF4ENIF1,NEK1,PCM1,IDH3B,YWHAH,PDCD11 |
| 6.858e-06 | -11.89 | IDH1 (isocitrate dehydrogenase (NADP(+)) 1, cytosolic) | protein interactions | 3417 | 63 | 25 | 17029 | 2761 |
PTMS,AGGF1,ANXA6,FAM49B,PHB2,MDH2,IDH3A,TKT,GLRX3,PCBP1,ARF4,ASF1B,CBX3,ADSS,C12orf10,CHMP4A,PEX5,ZHX1,DCK,CAB39,NUP62,TALDO1,IDH3B,CDK2,LTA4H |
| 6.858e-06 | -11.89 | NUP35 (nucleoporin 35) | protein interactions | 129401 | 63 | 25 | 17029 | 2761 |
HIVEP3,NDC1,NUP188,WDYHV1,PRKDC,ILF3,NUP54,TMEM216,RANGAP1,NUP155,ESYT1,FAM136A,UBE2I,NUP205,TMEM201,AFDN,AHCTF1,NUP107,NUP62,NUP153,MAVS,GLE1,NUP58,IFI16,SEH1L |
| 6.868e-06 | -11.89 | REACTOME_3_UTR_MEDIATED_TRANSLATIONAL_REGULATION | MSigDB lists | REACTOME_3_UTR_MEDIATED_TRANSLATIONAL_REGULATION | 105 | 34 | 17377 | 2626 |
RPS15,RPS2,RPLP2,EIF3D,RPL15,RPL11,RPL23A,EIF2S2,RPL17,RPL19,PABPC1,RPL29,RPL35,RPL8,RPL38,RPL6,RPS10,RPS24,EIF4H,RPL27A,RPS9,EIF3G,EIF3A,EIF3H,RPSA,RPL36,RPL37,EIF3K,RPL32,RPS27A,RPS14,RPLP1,FAU,RPS26 |
| 6.915e-06 | -11.88 | GSE7764_IL15_NK_CELL_24H_VS_SPLENOCYTE_UP | MSigDB lists | GSE7764_IL15_NK_CELL_24H_VS_SPLENOCYTE_UP | 174 | 49 | 17377 | 2626 |
RECQL,LYRM4,RRP15,PPP1R12A,GNPDA1,TMEM109,SDF2L1,WDR5,STMN1,NUP205,DTL,RNF121,DDX56,PSMD2,GART,EXOSC7,CNPY4,SLC35B4,GEMIN4,PRADC1,SLC25A1,LARS,ELOVL5,MAPRE2,HARS,WDR18,CYP20A1,TBRG4,DDX20,CDCA2,GSTCD,KRTCAP2,ARL5B,TARS,MAPK3,YIF1A,MAGED2,SLCO4A1,SLC19A1,MAGT1,ZHX1,USP20,AP1S1,TMEM101,SMAD1,TMEM159,DCAF5,BYSL,GCSH |
| 6.918e-06 | -11.88 | MODULE_567 | MSigDB lists | MODULE_567 | 92 | 31 | 17377 | 2626 |
ZNF207,HMGN1,MUT,ATP2C1,ANK3,ILF3,SLC25A22,NUP155,THNSL1,AGFG1,NDUFA7,SRSF5,BUD13,EDEM2,NCAPG,STAM,GLOD4,PRIM1,YIF1A,SUGP1,EIF3K,LYAR,FGFR3,UTP18,RPS14,CEBPG,CAB39,ATG13,PABPC1,HP1BP3,ABCC1 |
| 6.927e-06 | -11.88 | SUMO1 (small ubiquitin-like modifier 1) | protein interactions | 7341 | 172 | 51 | 17029 | 2761 |
NCOR2,ATXN3,EWSR1,FOXM1,TSC22D3,SLC2A1,MEF2A,TOP2B,GMCL1,BLM,UBE2I,PARK7,PSMD2,MDM2,PCNA,SP100,ETV6,NUP107,NUP153,ATF2,PABPC1,SENP1,NCOA2,SEH1L,CDC5L,SP3,BIRC3,FAM118B,ZMYM5,ATXN1,RANGAP1,TOPORS,BRCA1,PKM,RAD54B,CHAF1A,ZMYM3,FAS,HGS,CHD3,ZHX1,HIPK2,PRDX5,PML,PIAS2,NCOA1,HIPK3,SMAD4,CBX4,IFI16,SSSCA1 |
| 6.928e-06 | -11.88 | GO_ORGANELLAR_RIBOSOME | MSigDB lists | GO_ORGANELLAR_RIBOSOME | 67 | 25 | 17377 | 2626 |
MRPL9,MRPL42,MRPS2,MRPS15,MRPL39,MRPS26,MRPL12,MRPL43,MRPL16,NDUFA7,MRPS14,MRPL19,MRPL2,DAP3,MRPL55,MRPL27,MRPL34,MRPL40,MRPL48,MRPL11,MRPL21,MRPL13,MRPL3,NSUN4,MRPL32 |
| 7.055e-06 | -11.86 | clear_cell_renal_cell_carcinoma | COSMIC cancer mutations | clear_cell_renal_cell_carcinoma | 14301 | 2205 | 17385 | 2587 |
HECA,ZBTB10,ABCC10,HEXB,CCNL2,FBXO22,EEF2K,THAP4,RAD23B,ATP13A3,DNM2,FTSJ3,USP34,CCDC57,ERCC1,NRAS,EHMT1,KIF15,HNRNPF,WDHD1,MIER2,DIDO1,MCM2,RAB22A,SMAD2,MID1IP1,RPS27A,MYO18A,OGT,MPV17,SMAD1,ZNF75A,ANXA11,SLC25A33,ZNF720,SEC61G,GGA1,MUM1,CCZ1,TRIO,CUTA,RAB23,KCTD17,HAUS4,EIF2AK4,APH1B,PARN,CDC73,MYL6B,ATG4A,TMEM179B,PDXP,SMC3,GEMIN4,MVP,NUP85,PPP6R1,PABPC1,NSUN4,IFRD1,AGGF1,FOXK1,RBM42,GTPBP4,MAP7D1,MRPL16,ELK1,EIF4H,RDH11,MAGED2,KPNA1,ETS2,TYW5,WIPI2,RUFY3,PDLIM5,ACSF2,RHOG,STARD7,C5orf30,VTI1A,SLC35B2,INO80E,LCLAT1,RCOR3,CPNE3,KIAA1147,RBM23,AHCTF1,TBC1D22A,TBC1D14,GMEB1,NSFL1C,SEPT11,GPD1L,ZC3H3,ARL5A,SNX8,ERMP1,IDH3A,HTATIP2,MEF2D,GSTCD,TANC1,MAT2A,VPS26B,CORO1C,NSMCE2,CAMKMT,PPP5C,PITRM1,TUBB,COMMD10,ZNF445,SRSF6,HABP4,CCM2,FLOT1,BTN3A1,ATG2B,PPP1R3B,GOLM1,ZBTB45,HUWE1,ZNF260,NAA50,ANXA5,LTN1,KANSL2,UBE3B,NAP1L4,ZNF710,ST8SIA2,RPL22L1,MED22,SPTAN1,STAU1,DDX24,TCTEX1D2,TACC1,LDHA,LLPH,RAB3IP,TTC33,PICALM,SH3BP5,SLC19A1,ACOX1,FAM3C,AEN,PARP10,YWHAH,THAP5,GPATCH4,FAM129A,TRIM11,YTHDC2,SNX15,RBM8A,NENF,SND1,RUFY1,TRIM65,ZER1,PRNP,KRR1,RAB8A,NUP210,NT5DC1,NOC2L,EIF5,TACC3,VPS13B,RYBP,PTPN18,MIOS,MBLAC2,SNRPB,CDC6,UTP3,PBRM1,ODC1,USP21,TRAM2,FBXO28,BCL7C,ARRDC1,ADAM9,DVL1,NUMB,ZNF564,FUBP1,PARP12,ZCCHC9,CENPF,LAMTOR3,NCKAP1,LYRM2,RSAD1,TNS3,SUB1,RINL,KIF13B,MBD2,XPA,AHCY,GLE1,MRPL48,LRSAM1,HDHD2,NSDHL,AMD1,CAMSAP1,ZNF761,METTL22,STYXL1,APPL1,BBS12,ANKRD46,RXRB,SDHB,PCM1,GALNT2,TMEM168,NLRC5,RUVBL2,BTBD10,MYO9A,CCNB2,USP7,GLT8D1,SUCLG1,ARID2,TMX4,SLC2A1,ATP6V1B2,PCBP1,LYN,BCAP31,VAV1,TMEM69,MRPL50,PSMA6,ZNF473,ZNF302,BRPF3,TARDBP,BCAP29,CTDSP2,PRPF19,PPIF,KDM3B,MND1,CLCN3,BIRC3,RAB7A,ANKRD33B,PPIE,CHMP2B,VDAC1,EIF3H,IDE,DHX16,UHRF2,XRCC3,CHMP4B,PARD3,BCL2L12,C19orf53,MCM10,KLHL21,PDAP1,TMX3,ARF1,SLC12A9,TUBGCP2,DNAJB9,HOMER1,POLR1B,RNF5,RHOA,RPRD1A,BTAF1,TOP3A,ARHGEF12,PCGF1,DDX23,RAB18,CACNB1,TRIM26,PDCD6,ATP6V1D,L3MBTL3,NEIL3,CTBS,BBX,IMPDH1,NR2F2,PGAM1,HIPK3,IFI16,TXN,NUP188,H2AFZ,PNISR,TMEM203,PRKCSH,USP39,UBE2I,PARK7,SLC25A37,ZNF428,RAB4A,TRA2B,SUCLG2,TAF5L,SMARCE1,ZNF800,CDC5L,SGCE,OSBP2,NSUN2,USP22,EIF3A,ZMYM3,DOT1L,IWS1,ANKRD10,WAS,KIF18B,TPP2,C1orf109,ZMAT3,B4GALT2,PRPF38B,RECQL,C9orf78,EWSR1,GADD45G,RRM1,ACAP1,B4GALT1,CYCS,FAM136A,SUPT7L,TMEM165,NPLOC4,CNOT3,WDR48,SPAG5,RTKN,CEP104,KLHL5,LRRC8D,PPP4R1,MSH2,PIGG,FBXL7,OSTF1,SYTL3,FAM171A1,EIF5A,GCC2,PRIM2,ELL2,RDH10,MFNG,RPS24,GORASP2,CAPZA2,ADRB2,CCT8,MTR,PHF6,PFDN5,SLCO4A1,TTC13,GOLGA2,RBMX,MED15,PIAS2,APPL2,SAMD8,NUDT3,CDKN2A,ZNF511,ATXN3,RAF1,KIAA0232,C2orf49,EPM2A,CCNA2,MTMR4,BRI3,TP53BP2,AQR,RBM12B,ILKAP,CDK12,SAP30,BRD4,NARF,LRRC8A,ELP4,ABHD11,PKMYT1,ASB13,TRIM28,SUPT16H,EIF3K,CHMP4A,CBWD1,ATF6,XRCC4,PRPF4B,ADAM23,NDUFS1,DEPDC1,MECP2,SECISBP2,HMG20A,WWP2,JAKMIP1,SLC25A36,CCNK,DNAJC8,AXIN2,CITED2,JMJD4,KAT2A,TMEM126B,RABIF,ADSL,PACS1,BMS1,KCNQ1,OTUD3,ARSK,MACF1,KIF11,KLF6,COMMD4,SMAP2,FADD,SH3GLB1,MYO1F,CBX3,PPP1R11,DUSP11,DDX5,WDR62,TAF6,ESPL1,PURA,DDB1,DEF6,IPO4,FAM83G,UBL3,NAT9,PIGM,LYRM4,GPR132,UBE2Q1,PTP4A3,BRIX1,MRPL19,SF3B2,PCYOX1L,CDC42,SYNM,GOT2,JAZF1,HADHB,RPF2,CNNM3,CARM1,SRPK2,WDR41,LARS,ZCCHC10,CCDC138,LRBA,TMEM216,SUMF2,KMT2C,OGFR,PRPSAP1,MAN2A2,EIF4ENIF1,U2SURP,MIA2,ZNF268,VPS4A,ATP6V0E1,PPP1R2,PM20D2,XPNPEP3,RGS2,LYAR,POLR2I,TRAFD1,SUGP2,GBA,EIF2A,SYVN1,DAPK3,ARHGAP15,MASTL,UAP1,NFIL3,FN3KRP,YWHAZ,CTSA,TMEM14A,TOB1,TSEN15,ADNP2,TCF12,PRKAB1,MDH2,SMARCA4,ORC1,UBXN2A,IARS,CD3EAP,KIF14,EXOSC1,CS,CLTB,DNAL4,CSTF1,POU2AF1,UBQLN4,PGGT1B,SELPLG,SMU1,ATXN1,GLO1,OGDH,BICD2,CADM1,EDEM2,HERPUD2,TOLLIP,FANCE,PDHX,RPS9,ALKBH6,SURF4,DUS3L,ARNTL,ANP32E,FKBP5,CCDC125,ABCA1,PDCD2L,GCLM,RAE1,DCTN2,NUP54,CHIC2,PAWR,MXD4,DCUN1D4,PIP4K2A,XPR1,FERMT3,KIF5B,KLHL20,SEC24C,RRBP1,ARHGEF2,ANP32A,LDLRAD3,STAT3,MYO5A,NIPAL3,AMPD2,TXNL1,PHF20L1,DCAF6,FAM49B,TMEM39A,ATP2C1,RFFL,COG1,RCOR1,TFEB,LEMD2,UPF1,ELMO1,ZC3H7B,DTX4,ZMIZ1,TERF1,HRAS,CCDC93,FGFR1OP,PIGQ,CNTROB,PPP1R16B,MIS12,GSDMB,PDS5B,NUP153,SENP1,PGAP2,PLEKHM3,TRIM47,WDR11,AXIN1,SMG9,LONP2,NDUFV2,PHF23,CERK,SLC4A2,EZH1,ITGB5,LMNA,MCTS1,DDX56,EIF2S2,FOXN2,CARS2,PRRC2A,C16orf72,RB1CC1,ZMYND11,PGS1,MYBL2,UHRF1BP1,SRSF5,MPG,MATR3,CYB5A,NCDN,SETD3,TEX30,PTAR1,CNOT6,NDE1,EGLN1,ZNF207,ANKRD27,ABCA3,SARNP,IVNS1ABP,MON1B,RMI2,TMEM97,NIT2,NUF2,ZNF267,TCF19,TMEM161B,KTN1,APP,PRKD3,CLUAP1,ATP2A2,UTP18,GRSF1,DUT,ZCCHC2,ANAPC7,RNF19A,FAM76B,CLN6,GCC1,RNF169,ADCY7,ATP6V1G1,RNPS1,CDCA2,FKBP3,GPR137,DDX17,CHCHD3,PEX5,CDC16,HIPK2,MBOAT1,TICAM1,PDXK,ZBTB11,ANXA6,TMBIM4,GMCL1,UBE4A,IL21R,ETS1,WRB,ZNF92,PNO1,CAPN2,ADD3,SUV39H2,TTLL12,TPCN1,TMX1,HNRNPM,MFSD12,LDHB,PPP3CA,POLK,JTB,EMP3,MTMR12,PDE3B,KIF18A,CCDC6,MAPK6,LY75,SLC25A19,RGL1,PSAP,WDR76,IGBP1,FAF1,COX15,AGRN,THOC1,GNPDA1,GPBP1L1,PPP1R15B,CSNK2A1,EBNA1BP2,GIT2,BIRC2,ATPAF1,DLG5,ABL2,XRCC2,ZFYVE27,MCMBP,PTPRK,CDC37,SP3,HARS,GMFB,ESYT1,ANLN,RAB5B,RHEB,DPYSL3,TBC1D17,TONSL,NAGLU,ACTB,ZNF45,TMUB1,CTCF,ASAH1,DOCK11,CRLF3,ASXL2,NUS1,SLC27A4,AFF1,MDFIC,MAML1,CYTH1,NQO2,UTP15,EIF2AK1,EIF4G2,ZDHHC3,MOSPD3,ITPRIPL1,CDC27,SNAP23,PRMT7,KCTD7,CYLD,UGP2,COPE,ZADH2,GGPS1,RPAIN,RAD23A,PDK2,ATP6V0B,STRBP,DUS4L,PDCD2,SAP30L,CLPTM1,BTG2,DNAJC9,MTMR6,FRAT2,NFATC2,KDM1B,ARL5B,USP36,MRPL2,ATP1A1,CLK3,PSMD3,MAFK,CEP55,NDUFA11,DNAJC17,ZNF436,NCOA1,SLC25A39,ZC3HC1,ZNF146,ATXN7L2,CDC40,GOLIM4,RRP15,GNE,SMC6,ARFIP2,NKRF,BZW2,WRNIP1,SS18L1,CENPM,CAMK2G,MLEC,ZNF202,PPWD1,FAM50B,RHOT2,NEU1,TPD52L2,TWSG1,PGRMC1,GLG1,FAM126A,RPS6KC1,UBE2C,PPCS,NDUFB6,TMEM41B,ZDHHC8,PLXNA1,CCNB1,SLC20A1,COMMD6,ABHD14A,ASAP2,SNUPN,CNPY4,PLCL2,TFG,SEH1L,ATG9A,PBK,MKI67,DDX20,AMDHD2,GALNT7,SLC17A5,CCNF,FOXRED1,RBM47,PTER,WDR4,DHTKD1,TRAF5,HDAC2,PWWP2A,HSPH1,LIME1,CHTF18,KIF23,NOTCH2,PMF1,JMY,FKBP1A,SLC31A1,SNX18,ATIC,CTPS1,ATP6V0A2,PIKFYVE,RNF135,LPCAT1,EEF1D,TMED2,PHF10,FTL,DDX28,PIP4K2C,RIT1,PLEC,KDM3A,SF3A2,FAS,EPRS,ZNF777,TMEM54,PPP3R1,TCOF1,CABLES1,NRBP1,DNMT3A,CKLF,TRIP10,SF3B1,CAST,SUZ12,RPS6KA1,RAC1,GPR89A,OLA1,SNN,GNB2,FLAD1,APLP2,KDM2A,CDKN1B,TNPO2,TALDO1,GPX4,ATP13A1,RFC3,MAPRE2,ERF,CUL3,SLBP,KIAA1586,H2AFV,GAR1,POLG2,DHX57,NSA2,HSPA4,JAK1,TBL3,SEL1L,H2AFX,KLHDC4,PDCD11,ATMIN,POLQ,OTUD5,NCOR2,ANKRD13D,PKP4,CDCA3,SLC25A12,BLM,TMCC3,GTF2F1,CRAT,AHSA1,PRC1,UPF2,COPS7B,SLC38A10,CNOT6L,CNPY3,UBE2M,IFT46,TMEM160,TSHZ1,ZFP64,DENND4C,DENND1B,WDR18,RPL8,ILF3,LRRC1,RHOT1,MARK2,ECH1,PRDX1,PLD3,NUCB1,GNA12,FBXO21,PFDN4,TFDP1,STX18,KHSRP,CPEB2,SSSCA1,VPS29,S100PBP,MIB2,IER2,NOP2,UBN1,NF1,ALKBH5,MOGS,MAPK14,BECN1,SNAPC4,RNF103,BCAT2,MBD4,METTL14,IMPAD1,ZNHIT6,RCSD1,PHTF1,KIF22,ZBTB22,NFU1,OGG1,TRIM14,COPS8,FYTTD1,TRIM8,RRM2,SOX4,ABHD5,UBTF,CXXC4,PAF1,UEVLD,SPATA2,IARS2,ATXN2L,GALNT10,STARD3NL,PIGN,XPO7,SRRT,ZNF449,CAPZA1,GLTP,KIFAP3,BCL2,N4BP2,HP1BP3,VOPP1,THNSL1,ISG15,CAND1,GNAS,TSC1,RBM25,CDCA5,ZFP90,RBBP4,SMARCD1,MBD1,WASF2,MMACHC,MPHOSPH8,HNRNPUL2,CHD1,MEAF6,C2orf68,CCDC50,AKAP8,PARL,RPN2,CHTOP,F2R,FAM3A,TMEM14C,SCYL3,ABI1,RLIM,FAM172A,ZNF500,PSMB7,NLN,WIPF1,BOLA1,PEF1,EIF3G,BTBD1,TAB2,TULP3,CANT1,SCARB1,GAS2,USP11,SMURF1,PPP2R2D,TSPAN5,CDS2,MAGEH1,MRPL42,EYA1,CDK2AP2,MRPS26,LETMD1,KLF13,RGS1,MAN1A1,FBXO5,GART,TANK,PELO,BRD7,SAMD4B,ZDHHC18,GTF3C6,POLR3GL,WDR81,MEN1,ZNF407,MFN2,COX8A,MBD6,SRSF3,IDH3B,TATDN1,ATP6V1C1,TSC2,LACTB2,RBM4,ZNF275,ANKRD39,RPL23A,CDKN2C,DNAAF2,MECR,AP1M1,UPRT,CRY2,ECD,RNF26,TIPARP,LRRC59,ANKRD9,RHBDD2,MGAT5,BAK1,ZNF559,RHOBTB3,GABPA,NUTF2,ARF4,KRIT1,AHNAK,RAD18,PDRG1,RNASEL,PDCD4,SMNDC1,HIVEP3,KIAA0100,CLSPN,RHOC,DHX9,PDCD7,PSMD9,COPB2,CD59,TFAP4,RNFT1,MEGF8,RIMS3,EFTUD2,FBXO7,CPSF4,MRPL21,PHKG2,LUC7L2,SRSF11,EIF3L,MTA2,TYW1,USP10,ITM2A,SSR2,BCLAF1,SFXN5,PDLIM1,TXNDC16,MRPL3,ALS2,FAM72A,TRIM41,KARS,ANK3,PTTG1,TPX2,TBC1D13,REPS1,FBXL6,MTA1,UBA5,CLCN6,INTS12,RPRD1B,CGGBP1,CPNE1,SEC61B,GOPC,E2F3,CIRBP,CRNKL1,PFKFB3,RAB1A,GIGYF1,TMEM184C,PPP2CA,KIF2A,CCDC14,LSM6,RNF38,SNRPG,DMWD,USP13,MZT1,ZFP91,TRMT6,IP6K2,WDR5,SLC25A43,IFT27,PMVK,NEIL2,RPA2,PSMD2,CLIC4,PDCD10,ITGB8,ARF5,ARHGEF1,FBXL19,GTF2H2,UTP20,MAGT1,GPS2,DBI,SSNA1,CD81,TMEM131,WDR13,FANCI,PAPOLA,CREM,TET3,FANCL,GLIS2,IL6ST,INTS1,POP7,SLC44A1,MTPN,ASB6,PLK1,SEPT9,CELSR2,RBX1,RAD51AP1,ZBED5,CKAP2L,PSMG1,UBE2V1,EAF2,IL12RB1,LUC7L,NECAP2,C1orf122,ALG3,TRIM4,AGPAT2,CHD3,ZNF367,E2F4,PRPF4,KPNA2,BEND6,CLN3,DNAJC30,FAM208A,NGLY1,POT1,MYL12B,RMND5A,HJURP,PHB2,DNAJB2,NKD2,SDC2,KLC1,CDK13,ADCK5,COX4I1,DNAJB1,RAB6A,ARID1B,C1GALT1,MLX,UBE2Q2,CCP110,ZNF746,CTR9,ABHD2,DCAF8,ACSL3,LDB1,MAP4K3,ARMC8,RBM38,NMT2,IRF5,HAUS8,MBIP,ORMDL2,COX7A2L,ZDHHC7,SIL1,DTD1,UNC13C,BCCIP,SART1,TRAF7,NDUFAF2,TOR1AIP1,ZNF416,TM9SF3,RRAGC,ZNF121,OIP5,NRF1,WDR44,PPME1,PIN1,EFCAB11,RPAP1,CABLES2,LMAN1,AHCYL1,TOP1MT,STRAP,SPSB3,ZNF583,SNX25,ARHGAP17,ZNF780B,KIAA0040,NUP155,DCLRE1C,MRPS14,RHBDF2,SUGP1,RBL1,FASTK,UBXN2B,STK38,AP1S1,SPRYD4,SLC22A23,CHID1,SMAD4,RAD51D,SLC30A9,CMAS,UNK,NADSYN1,HMGN3,NCAPG,SCYL2,FZD6,HERC3,GTPBP3,CTSS,ORC3,RNLS,YTHDC1,ACP2,HMGN5,TUFM,RANGAP1,PNPLA8,HAGH,API5,ZFR,SEC23IP,E2F1,TMEM219,USP20,RBPJ,PDCD6IP,MAX,LUZP1,GXYLT1,ADAM10,CXXC1,TSC22D3,AP3M2,CUL1,GYG1,NANS,OAT,MYEF2,ANKRD26,PA2G4,NOL11,FIZ1,ZNF200,MARCH2,SLC26A2,SRP72,KLF10,LACTB,RFC2,CBFB,RAB2B,PRIM1,MAP3K4,HHEX,LUC7L3,RPS14,MAP4,MRPL27,BTF3,PTPDC1,NMD3,PTOV1,COX5B,DNAJC5,SCOC,DHPS,ANKH,VAV2,PRKAA1,C16orf87,GSPT2,DLGAP4,PXMP2,PRPF39,PSEN1,ZNF79,PDXDC1,VPS25,YY1AP1,C12orf10,RPN1,LHX8,ZNRF2,TPST1,DAPK1,CYC1,SOCS5,FDFT1,PIGT,EMB,WDR1,ZNF574,EXOSC9,ARID1A,PTTG1IP,FXR1,GOSR1,MAP2K2,TWISTNB,AKAP1,XRCC5,HMGN2,PI4K2A,CAT,DERL1,MTHFD2,HSPBP1,CEBPG,ARAP1,USP32,FAM83D,CABIN1,GPI,CYTIP,TP53RK,REPS2,RAB11B,UROD,SLC39A13,POMP,BCL2L1,DECR1,RALB,SIAH1,ADCY9,LPIN2,MRPS27,SOCS6,TTC3,ANKLE2,CDC123,OAF,VDAC2,EML4,ERC1,AMZ2,ANKZF1,RAD51C,DSN1,DDOST,DGCR8,SAFB,LMBR1,NCLN,BEND3,EYA2,DYNC1LI2,MANBA,SLC41A1,B4GALT5,FAM76A,TKT,CBLL1,ARGLU1,LANCL1,POFUT1,FAM8A1,HEATR5B,HLA-A,RFWD3,FUT8,BTF3L4,PTPN11,MRPL54,FEM1B,RPL19,CNN2,NDUFA3,MTX2,MSH6,PDLIM2,LONRF3,FBXO9,GUF1,RPL32,ZHX1,NDUFS5,WDR91,GPR89B,RORB,POLA2,ZNF76,COPA,UQCR10,PHRF1,HMGXB3,ABCB10,COMMD5,MAP1LC3B,DST,RAB35,GPATCH1,TCEA1,DEAF1,SNRNP200,LAP3,NCK1,VHL,SREK1,ARHGDIB,PITPNB,HSPB11,BRWD1,PPM1G,SH3GLB2,CRCP,BAZ1B,CAB39,ACBD4,STK11,CLU,CHEK2,ZSWIM3,TSTD2,MRPL13,CHPT1,DCAF5,CAPN1,UBE2D3,PPP1R12A,ZCCHC8,NACA,C19orf25,RPL15,PCSK7,EPN1,THRAP3,QSOX2,TTF1,NUP205,CHKA,DTL,MED10,ZRANB1,MCPH1,SLC12A2,ATP6V0D1,CSNK1G3,CREG1,NUDT4,VKORC1,SLTM,EVC2,KLHL15,SIAH2,SLC16A1,EHD4,SNRNP70,C11orf1,N4BP2L2,SNX27,CHMP2A,CORO7,FEZ2,PMS2,UCK2,UCK1,CLCC1,EXT2,MXD1,USP5,HNRNPA2B1,SAP130,NVL,PPP6C,CYB5R1,ZNF770,EBAG9,RNF25,PCGF6,METTL2A,HNRNPR,STAT6,HPS5,MAPK1,BRD9,TMEM33,DNAJC2,TRIP12,SHPRH,SCYL1,VPS45,MYO9B,GFM2,SPPL2A,FASTKD3,FGFR3,MZT2A,PPIG,ZDHHC13,H2AFY,NDUFS8,ATG13,ERI3,FBL,FRMD8,SLC35A1,MICAL3,B3GALT6,ELOVL5,HEMK1,TIMMDC1,HELB,PSPC1,MIER1,SCFD2,NDRG3,CDK11A,MTMR3,MEGF9,CENPT,PLOD3,RAB3IL1,ZSWIM6,RAB14,ADD1,KDM4A,MRPS15,XIAP,DHX8,GLUD1,ANKRD23,PABPC4,CDK5,CALM2,PSMD1,NEK6,NSRP1,RABGAP1L,SRSF4,FNIP2,KCNAB2,PCBP2,MLST8,PLK3,ZNF672,HSDL1,TOPORS,MCL1,PPFIA3,SMC2,ICMT,SLC50A1,STOML2,LIMK1,PRDX5,ATE1,MLYCD,ST3GAL2,FBXL3,TFDP2,E2F2,PFKP,AAAS,DDX42,SSRP1,MRPL9,STRN4,TOP2B,ZNRF3,TMED3,DDRGK1,RAVER2,GNS,INTS7,INPP5A,MCM5,PHF14,ZNF326,UBE2QL1,NAGPA,ETV3,TSPAN31,DHX29,TEX10,MAN1B1,CBFA2T2,ABCF1,RHOB,LRRC14B,DTWD1,PTPRF,SCARB2,OSBPL11,DUSP3,SLAIN1,MDH1,HEXA,RNF139,SNX14,TRERF1,UBR2,CHD1L,ACTR3,WDTC1,MYH9,NIPA2,PRKACA,SAFB2,ANKIB1,STAM,ARL6IP6,RAB21,ZKSCAN1,DDA1,NUP107,ANKRD13C,CEP63,ATF2,RBM15,DCTN1,SHOC2,PSRC1,MAP4K4,WBP2,ATP6V0A1,NUSAP1,NDUFA7,DNAJA1,TAF2,C19orf54,SEC61A1,WDR7,FUS,GEN1,LRP8,COIL,LRCH1,ZNF786,RPS2,SESTD1,TRAK1,JMJD6,SIKE1,AKT1S1,KRI1,FBXO3,ERH,NDUFB4,PPP1R8,PRDM4,GTSE1,GEMIN6,DCP1A,IMPA2,NUDC,PDPK1,TK1,TNFAIP3,GALC,ZNF512,KIAA0930,DDX39A,RPA1,ZNF862,ZNF180,KEAP1,POLE,PITX1,CAPN7,LRPPRC,PML,HMGB2,USF2,ANAPC4,DDX47,MCCC1,S1PR2,SEC16A,SSR1,LIN9,PCNA,TRMU,ETV6,PIK3R2,TXLNA,MYBL1,CCAR1,MRPL32,ABCC5,BAZ2A,PBXIP1,TLK1,EZR,LNX2,LRP5,BRCA1,PRKRA,STX16,EPB41,OPTN,SEPT1,SOCS4,QRSL1,PIEZO1,OSGEPL1,NAA60,GEMIN7,SEPHS2,LZTR1,RACGAP1,PPP3CB,B4GALT4,RLF,RAPGEF6,SNRNP25,RB1,VASP,VMP1,PPIL2,TIMELESS,AHDC1,ALDH18A1,TMEM8A,PREB,ABCC1,TRAPPC9,AACS,MEMO1,KRAS,RTF1,UBE4B,LY6E,PSMC4,GOLGA4,PALB2,SYNCRIP,PRPS2,NIPA1,TIGD2,RNF114,FOXM1,MRPL39,XAB2,SUMO2,DUSP22,RPL11,CSDE1,MDM2,CORO1A,METTL9,MINPP1,POC5,DVL2,GM2A,PSMA8,COQ10B,CPOX,PRPF3,TXNL4A,SRSF1,DNAJC10,SCAP,ZNF700,PLEKHG4B,TIMM17A,FAU,LTA4H,USP53,INTS2,CTDP1,CDT1,ARID5A,SUMF1,GGA2,CSNK1A1,AP3S1,RMI1,TFRC,PTPN2,IRF4,STARD9,SLC1A4,CWC27,SLC35B4,DDX31,ABCD1,RPAP3,CNTN5,SNX2,ZMYM5,CHCHD6,BSDC1,CDKN2AIPNL,FBXO41,KPNA4,BIRC5,TFE3,CDCA7L,PKD2,ACADM,CHMP7,SAT2,GCSH,ZNF496,TMEM109,TAP1,YTHDF3,NHLRC3,IKBIP,ELMOD2,KIFC1,DBNDD1,CYB5RL,PARPBP,CDC25B,DNMT1,NOL12,ORAI2,USO1,AKT2,NOL8,GNG7,AURKB,SLC25A5,ZFAND5,MAK16,STT3A,EIF2D,ITGB1,PTPN7,RRS1,ARRB2,RTN3,ZNF598,DDX58,WSB2,PPIB,MUT,HLA-E,NDUFA4,METTL3,CFLAR,NDUFS4,RNF121,MEX3C,HDAC7,BDH1,PCYT2,GNAI2,ANKHD1,TERF2,MORC3,KCTD20,SEPT8,DCTD,PKM,ADSS,SERTAD2,NSF,ACLY,LPCAT4,VCPIP1,PPP6R2,PPP6R3,MAP3K5,YY1,CDK2,RNF14,ZC3HAV1,ZBTB37,URB2,EIF3D,MAGED1,KLHL18,SLC25A44,AP1B1,SDHA,PAIP2,PHC2,CRKL,TERF2IP,ZNF75D,SHC1,UCHL5,NAA35,TMBIM1,CDKN2AIP,CCT2,MKLN1,HMGN4,GALK2,CDC23,SHCBP1,AP4E1,PRDM11,VEZF1,PPP2R5A,ACYP1,STAT1,PPA2,TRIM32,RHEBL1,C1orf112,TCF3,BRAP,MYNN,RAB11A,REEP5,FOXO3,MAD2L2,PIP5K1C,RBM17,MAT2B,PTEN,CENPJ,CREB1,NCOA2,PACS2,SMC4,NEK7,NET1,PARP4,TBRG4,ANAPC2,HGS,TTLL4,MFAP1,CCDC69,BRWD3,ESYT2,SKA3,NPHP4,UBE2E2,PLXNC1,ST13,ZNF107,SLC29A1,KIF2C,AGFG1,SIRT2,USP48,SNRPD3,FKBP2,EDC3,UBLCP1,ZNF804A,RAP1A,THADA,EIF4A3,AP3S2,ATG3,DPYSL2,PPP1R12C,AKR1B1,NDUFB9,TTC4,TECR,ARID4A,FGFR1OP2,TIMM50,TDP1,DPM1,FOPNL,SLC16A7,SLC25A22,WDR82,STK17B,DHX15,CHAF1A,GEMIN5,COPS6,SASS6,RPS26,PSMC1,SLC12A7,TBC1D12,TM9SF4,ZNF768,MED13L,TIA1,MEF2A,EPHX2,PITHD1,RHBDD1,NFATC3,ZNF335,YBX1,KNTC1,UBE3C,ACAD8,ZNF189,ALDH9A1,CIC,SEPT7,NAP1L1,ODF2,EXOC4,NUP62,PITPNA,KIAA1328,NAA20,PTDSS1,PDSS2,C7orf26,IMMT,ASH1L,CHERP,WDYHV1,PLAGL2,IRF3,CHKB,TWF2,PAIP1,ANKRD28,FARSA,ANKLE1,SAR1A,APOOL,PDIA6,ACSL5,AZI2,GFER,RAD54B,DAP3,TMEM41A,ZNF317,AKNA,REEP4,CBX4,KIF3B,GOLPH3L,SH2D3A,CASP6,TOR3A,SRGN,DBF4,MFSD10,CTNNBL1,YIF1B,CLDND1,TTC17,GINS1,CSNK1G2,TELO2,HMGN1,ADAM17,NASP,ASPM,PPP1R21,PRKAR1B,SYMPK,TARS,MAPK3,HLA-B,PLAA,ATAD2,ZNF330,OSBPL8,KBTBD7,PREPL |
| 7.055e-06 | -11.86 | kidney-carcinoma-clear_cell_renal_cell_carcinoma | COSMIC cancer mutations | kidney-carcinoma-clear_cell_renal_cell_carcinoma | 14301 | 2205 | 17385 | 2587 |
HECA,ZBTB10,ABCC10,HEXB,CCNL2,FBXO22,EEF2K,THAP4,RAD23B,ATP13A3,DNM2,FTSJ3,USP34,CCDC57,ERCC1,NRAS,EHMT1,KIF15,HNRNPF,WDHD1,MIER2,DIDO1,MCM2,RAB22A,SMAD2,MID1IP1,RPS27A,MYO18A,OGT,MPV17,SMAD1,ZNF75A,ANXA11,SLC25A33,ZNF720,SEC61G,GGA1,MUM1,CCZ1,TRIO,CUTA,RAB23,KCTD17,HAUS4,EIF2AK4,APH1B,PARN,CDC73,MYL6B,ATG4A,TMEM179B,PDXP,SMC3,GEMIN4,MVP,NUP85,PPP6R1,PABPC1,NSUN4,IFRD1,AGGF1,FOXK1,RBM42,GTPBP4,MAP7D1,MRPL16,ELK1,EIF4H,RDH11,MAGED2,KPNA1,ETS2,TYW5,WIPI2,RUFY3,PDLIM5,ACSF2,RHOG,STARD7,C5orf30,VTI1A,SLC35B2,INO80E,LCLAT1,RCOR3,CPNE3,KIAA1147,RBM23,AHCTF1,TBC1D22A,TBC1D14,GMEB1,NSFL1C,SEPT11,GPD1L,ZC3H3,ARL5A,SNX8,ERMP1,IDH3A,HTATIP2,MEF2D,GSTCD,TANC1,MAT2A,VPS26B,CORO1C,NSMCE2,CAMKMT,PPP5C,PITRM1,TUBB,COMMD10,ZNF445,SRSF6,HABP4,CCM2,FLOT1,BTN3A1,ATG2B,PPP1R3B,GOLM1,ZBTB45,HUWE1,ZNF260,NAA50,ANXA5,LTN1,KANSL2,UBE3B,NAP1L4,ZNF710,ST8SIA2,RPL22L1,MED22,SPTAN1,STAU1,DDX24,TCTEX1D2,TACC1,LDHA,LLPH,RAB3IP,TTC33,PICALM,SH3BP5,SLC19A1,ACOX1,FAM3C,AEN,PARP10,YWHAH,THAP5,GPATCH4,FAM129A,TRIM11,YTHDC2,SNX15,RBM8A,NENF,SND1,RUFY1,TRIM65,ZER1,PRNP,KRR1,RAB8A,NUP210,NT5DC1,NOC2L,EIF5,TACC3,VPS13B,RYBP,PTPN18,MIOS,MBLAC2,SNRPB,CDC6,UTP3,PBRM1,ODC1,USP21,TRAM2,FBXO28,BCL7C,ARRDC1,ADAM9,DVL1,NUMB,ZNF564,FUBP1,PARP12,ZCCHC9,CENPF,LAMTOR3,NCKAP1,LYRM2,RSAD1,TNS3,SUB1,RINL,KIF13B,MBD2,XPA,AHCY,GLE1,MRPL48,LRSAM1,HDHD2,NSDHL,AMD1,CAMSAP1,ZNF761,METTL22,STYXL1,APPL1,BBS12,ANKRD46,RXRB,SDHB,PCM1,GALNT2,TMEM168,NLRC5,RUVBL2,BTBD10,MYO9A,CCNB2,USP7,GLT8D1,SUCLG1,ARID2,TMX4,SLC2A1,ATP6V1B2,PCBP1,LYN,BCAP31,VAV1,TMEM69,MRPL50,PSMA6,ZNF473,ZNF302,BRPF3,TARDBP,BCAP29,CTDSP2,PRPF19,PPIF,KDM3B,MND1,CLCN3,BIRC3,RAB7A,ANKRD33B,PPIE,CHMP2B,VDAC1,EIF3H,IDE,DHX16,UHRF2,XRCC3,CHMP4B,PARD3,BCL2L12,C19orf53,MCM10,KLHL21,PDAP1,TMX3,ARF1,SLC12A9,TUBGCP2,DNAJB9,HOMER1,POLR1B,RNF5,RHOA,RPRD1A,BTAF1,TOP3A,ARHGEF12,PCGF1,DDX23,RAB18,CACNB1,TRIM26,PDCD6,ATP6V1D,L3MBTL3,NEIL3,CTBS,BBX,IMPDH1,NR2F2,PGAM1,HIPK3,IFI16,TXN,NUP188,H2AFZ,PNISR,TMEM203,PRKCSH,USP39,UBE2I,PARK7,SLC25A37,ZNF428,RAB4A,TRA2B,SUCLG2,TAF5L,SMARCE1,ZNF800,CDC5L,SGCE,OSBP2,NSUN2,USP22,EIF3A,ZMYM3,DOT1L,IWS1,ANKRD10,WAS,KIF18B,TPP2,C1orf109,ZMAT3,B4GALT2,PRPF38B,RECQL,C9orf78,EWSR1,GADD45G,RRM1,ACAP1,B4GALT1,CYCS,FAM136A,SUPT7L,TMEM165,NPLOC4,CNOT3,WDR48,SPAG5,RTKN,CEP104,KLHL5,LRRC8D,PPP4R1,MSH2,PIGG,FBXL7,OSTF1,SYTL3,FAM171A1,EIF5A,GCC2,PRIM2,ELL2,RDH10,MFNG,RPS24,GORASP2,CAPZA2,ADRB2,CCT8,MTR,PHF6,PFDN5,SLCO4A1,TTC13,GOLGA2,RBMX,MED15,PIAS2,APPL2,SAMD8,NUDT3,CDKN2A,ZNF511,ATXN3,RAF1,KIAA0232,C2orf49,EPM2A,CCNA2,MTMR4,BRI3,TP53BP2,AQR,RBM12B,ILKAP,CDK12,SAP30,BRD4,NARF,LRRC8A,ELP4,ABHD11,PKMYT1,ASB13,TRIM28,SUPT16H,EIF3K,CHMP4A,CBWD1,ATF6,XRCC4,PRPF4B,ADAM23,NDUFS1,DEPDC1,MECP2,SECISBP2,HMG20A,WWP2,JAKMIP1,SLC25A36,CCNK,DNAJC8,AXIN2,CITED2,JMJD4,KAT2A,TMEM126B,RABIF,ADSL,PACS1,BMS1,KCNQ1,OTUD3,ARSK,MACF1,KIF11,KLF6,COMMD4,SMAP2,FADD,SH3GLB1,MYO1F,CBX3,PPP1R11,DUSP11,DDX5,WDR62,TAF6,ESPL1,PURA,DDB1,DEF6,IPO4,FAM83G,UBL3,NAT9,PIGM,LYRM4,GPR132,UBE2Q1,PTP4A3,BRIX1,MRPL19,SF3B2,PCYOX1L,CDC42,SYNM,GOT2,JAZF1,HADHB,RPF2,CNNM3,CARM1,SRPK2,WDR41,LARS,ZCCHC10,CCDC138,LRBA,TMEM216,SUMF2,KMT2C,OGFR,PRPSAP1,MAN2A2,EIF4ENIF1,U2SURP,MIA2,ZNF268,VPS4A,ATP6V0E1,PPP1R2,PM20D2,XPNPEP3,RGS2,LYAR,POLR2I,TRAFD1,SUGP2,GBA,EIF2A,SYVN1,DAPK3,ARHGAP15,MASTL,UAP1,NFIL3,FN3KRP,YWHAZ,CTSA,TMEM14A,TOB1,TSEN15,ADNP2,TCF12,PRKAB1,MDH2,SMARCA4,ORC1,UBXN2A,IARS,CD3EAP,KIF14,EXOSC1,CS,CLTB,DNAL4,CSTF1,POU2AF1,UBQLN4,PGGT1B,SELPLG,SMU1,ATXN1,GLO1,OGDH,BICD2,CADM1,EDEM2,HERPUD2,TOLLIP,FANCE,PDHX,RPS9,ALKBH6,SURF4,DUS3L,ARNTL,ANP32E,FKBP5,CCDC125,ABCA1,PDCD2L,GCLM,RAE1,DCTN2,NUP54,CHIC2,PAWR,MXD4,DCUN1D4,PIP4K2A,XPR1,FERMT3,KIF5B,KLHL20,SEC24C,RRBP1,ARHGEF2,ANP32A,LDLRAD3,STAT3,MYO5A,NIPAL3,AMPD2,TXNL1,PHF20L1,DCAF6,FAM49B,TMEM39A,ATP2C1,RFFL,COG1,RCOR1,TFEB,LEMD2,UPF1,ELMO1,ZC3H7B,DTX4,ZMIZ1,TERF1,HRAS,CCDC93,FGFR1OP,PIGQ,CNTROB,PPP1R16B,MIS12,GSDMB,PDS5B,NUP153,SENP1,PGAP2,PLEKHM3,TRIM47,WDR11,AXIN1,SMG9,LONP2,NDUFV2,PHF23,CERK,SLC4A2,EZH1,ITGB5,LMNA,MCTS1,DDX56,EIF2S2,FOXN2,CARS2,PRRC2A,C16orf72,RB1CC1,ZMYND11,PGS1,MYBL2,UHRF1BP1,SRSF5,MPG,MATR3,CYB5A,NCDN,SETD3,TEX30,PTAR1,CNOT6,NDE1,EGLN1,ZNF207,ANKRD27,ABCA3,SARNP,IVNS1ABP,MON1B,RMI2,TMEM97,NIT2,NUF2,ZNF267,TCF19,TMEM161B,KTN1,APP,PRKD3,CLUAP1,ATP2A2,UTP18,GRSF1,DUT,ZCCHC2,ANAPC7,RNF19A,FAM76B,CLN6,GCC1,RNF169,ADCY7,ATP6V1G1,RNPS1,CDCA2,FKBP3,GPR137,DDX17,CHCHD3,PEX5,CDC16,HIPK2,MBOAT1,TICAM1,PDXK,ZBTB11,ANXA6,TMBIM4,GMCL1,UBE4A,IL21R,ETS1,WRB,ZNF92,PNO1,CAPN2,ADD3,SUV39H2,TTLL12,TPCN1,TMX1,HNRNPM,MFSD12,LDHB,PPP3CA,POLK,JTB,EMP3,MTMR12,PDE3B,KIF18A,CCDC6,MAPK6,LY75,SLC25A19,RGL1,PSAP,WDR76,IGBP1,FAF1,COX15,AGRN,THOC1,GNPDA1,GPBP1L1,PPP1R15B,CSNK2A1,EBNA1BP2,GIT2,BIRC2,ATPAF1,DLG5,ABL2,XRCC2,ZFYVE27,MCMBP,PTPRK,CDC37,SP3,HARS,GMFB,ESYT1,ANLN,RAB5B,RHEB,DPYSL3,TBC1D17,TONSL,NAGLU,ACTB,ZNF45,TMUB1,CTCF,ASAH1,DOCK11,CRLF3,ASXL2,NUS1,SLC27A4,AFF1,MDFIC,MAML1,CYTH1,NQO2,UTP15,EIF2AK1,EIF4G2,ZDHHC3,MOSPD3,ITPRIPL1,CDC27,SNAP23,PRMT7,KCTD7,CYLD,UGP2,COPE,ZADH2,GGPS1,RPAIN,RAD23A,PDK2,ATP6V0B,STRBP,DUS4L,PDCD2,SAP30L,CLPTM1,BTG2,DNAJC9,MTMR6,FRAT2,NFATC2,KDM1B,ARL5B,USP36,MRPL2,ATP1A1,CLK3,PSMD3,MAFK,CEP55,NDUFA11,DNAJC17,ZNF436,NCOA1,SLC25A39,ZC3HC1,ZNF146,ATXN7L2,CDC40,GOLIM4,RRP15,GNE,SMC6,ARFIP2,NKRF,BZW2,WRNIP1,SS18L1,CENPM,CAMK2G,MLEC,ZNF202,PPWD1,FAM50B,RHOT2,NEU1,TPD52L2,TWSG1,PGRMC1,GLG1,FAM126A,RPS6KC1,UBE2C,PPCS,NDUFB6,TMEM41B,ZDHHC8,PLXNA1,CCNB1,SLC20A1,COMMD6,ABHD14A,ASAP2,SNUPN,CNPY4,PLCL2,TFG,SEH1L,ATG9A,PBK,MKI67,DDX20,AMDHD2,GALNT7,SLC17A5,CCNF,FOXRED1,RBM47,PTER,WDR4,DHTKD1,TRAF5,HDAC2,PWWP2A,HSPH1,LIME1,CHTF18,KIF23,NOTCH2,PMF1,JMY,FKBP1A,SLC31A1,SNX18,ATIC,CTPS1,ATP6V0A2,PIKFYVE,RNF135,LPCAT1,EEF1D,TMED2,PHF10,FTL,DDX28,PIP4K2C,RIT1,PLEC,KDM3A,SF3A2,FAS,EPRS,ZNF777,TMEM54,PPP3R1,TCOF1,CABLES1,NRBP1,DNMT3A,CKLF,TRIP10,SF3B1,CAST,SUZ12,RPS6KA1,RAC1,GPR89A,OLA1,SNN,GNB2,FLAD1,APLP2,KDM2A,CDKN1B,TNPO2,TALDO1,GPX4,ATP13A1,RFC3,MAPRE2,ERF,CUL3,SLBP,KIAA1586,H2AFV,GAR1,POLG2,DHX57,NSA2,HSPA4,JAK1,TBL3,SEL1L,H2AFX,KLHDC4,PDCD11,ATMIN,POLQ,OTUD5,NCOR2,ANKRD13D,PKP4,CDCA3,SLC25A12,BLM,TMCC3,GTF2F1,CRAT,AHSA1,PRC1,UPF2,COPS7B,SLC38A10,CNOT6L,CNPY3,UBE2M,IFT46,TMEM160,TSHZ1,ZFP64,DENND4C,DENND1B,WDR18,RPL8,ILF3,LRRC1,RHOT1,MARK2,ECH1,PRDX1,PLD3,NUCB1,GNA12,FBXO21,PFDN4,TFDP1,STX18,KHSRP,CPEB2,SSSCA1,VPS29,S100PBP,MIB2,IER2,NOP2,UBN1,NF1,ALKBH5,MOGS,MAPK14,BECN1,SNAPC4,RNF103,BCAT2,MBD4,METTL14,IMPAD1,ZNHIT6,RCSD1,PHTF1,KIF22,ZBTB22,NFU1,OGG1,TRIM14,COPS8,FYTTD1,TRIM8,RRM2,SOX4,ABHD5,UBTF,CXXC4,PAF1,UEVLD,SPATA2,IARS2,ATXN2L,GALNT10,STARD3NL,PIGN,XPO7,SRRT,ZNF449,CAPZA1,GLTP,KIFAP3,BCL2,N4BP2,HP1BP3,VOPP1,THNSL1,ISG15,CAND1,GNAS,TSC1,RBM25,CDCA5,ZFP90,RBBP4,SMARCD1,MBD1,WASF2,MMACHC,MPHOSPH8,HNRNPUL2,CHD1,MEAF6,C2orf68,CCDC50,AKAP8,PARL,RPN2,CHTOP,F2R,FAM3A,TMEM14C,SCYL3,ABI1,RLIM,FAM172A,ZNF500,PSMB7,NLN,WIPF1,BOLA1,PEF1,EIF3G,BTBD1,TAB2,TULP3,CANT1,SCARB1,GAS2,USP11,SMURF1,PPP2R2D,TSPAN5,CDS2,MAGEH1,MRPL42,EYA1,CDK2AP2,MRPS26,LETMD1,KLF13,RGS1,MAN1A1,FBXO5,GART,TANK,PELO,BRD7,SAMD4B,ZDHHC18,GTF3C6,POLR3GL,WDR81,MEN1,ZNF407,MFN2,COX8A,MBD6,SRSF3,IDH3B,TATDN1,ATP6V1C1,TSC2,LACTB2,RBM4,ZNF275,ANKRD39,RPL23A,CDKN2C,DNAAF2,MECR,AP1M1,UPRT,CRY2,ECD,RNF26,TIPARP,LRRC59,ANKRD9,RHBDD2,MGAT5,BAK1,ZNF559,RHOBTB3,GABPA,NUTF2,ARF4,KRIT1,AHNAK,RAD18,PDRG1,RNASEL,PDCD4,SMNDC1,HIVEP3,KIAA0100,CLSPN,RHOC,DHX9,PDCD7,PSMD9,COPB2,CD59,TFAP4,RNFT1,MEGF8,RIMS3,EFTUD2,FBXO7,CPSF4,MRPL21,PHKG2,LUC7L2,SRSF11,EIF3L,MTA2,TYW1,USP10,ITM2A,SSR2,BCLAF1,SFXN5,PDLIM1,TXNDC16,MRPL3,ALS2,FAM72A,TRIM41,KARS,ANK3,PTTG1,TPX2,TBC1D13,REPS1,FBXL6,MTA1,UBA5,CLCN6,INTS12,RPRD1B,CGGBP1,CPNE1,SEC61B,GOPC,E2F3,CIRBP,CRNKL1,PFKFB3,RAB1A,GIGYF1,TMEM184C,PPP2CA,KIF2A,CCDC14,LSM6,RNF38,SNRPG,DMWD,USP13,MZT1,ZFP91,TRMT6,IP6K2,WDR5,SLC25A43,IFT27,PMVK,NEIL2,RPA2,PSMD2,CLIC4,PDCD10,ITGB8,ARF5,ARHGEF1,FBXL19,GTF2H2,UTP20,MAGT1,GPS2,DBI,SSNA1,CD81,TMEM131,WDR13,FANCI,PAPOLA,CREM,TET3,FANCL,GLIS2,IL6ST,INTS1,POP7,SLC44A1,MTPN,ASB6,PLK1,SEPT9,CELSR2,RBX1,RAD51AP1,ZBED5,CKAP2L,PSMG1,UBE2V1,EAF2,IL12RB1,LUC7L,NECAP2,C1orf122,ALG3,TRIM4,AGPAT2,CHD3,ZNF367,E2F4,PRPF4,KPNA2,BEND6,CLN3,DNAJC30,FAM208A,NGLY1,POT1,MYL12B,RMND5A,HJURP,PHB2,DNAJB2,NKD2,SDC2,KLC1,CDK13,ADCK5,COX4I1,DNAJB1,RAB6A,ARID1B,C1GALT1,MLX,UBE2Q2,CCP110,ZNF746,CTR9,ABHD2,DCAF8,ACSL3,LDB1,MAP4K3,ARMC8,RBM38,NMT2,IRF5,HAUS8,MBIP,ORMDL2,COX7A2L,ZDHHC7,SIL1,DTD1,UNC13C,BCCIP,SART1,TRAF7,NDUFAF2,TOR1AIP1,ZNF416,TM9SF3,RRAGC,ZNF121,OIP5,NRF1,WDR44,PPME1,PIN1,EFCAB11,RPAP1,CABLES2,LMAN1,AHCYL1,TOP1MT,STRAP,SPSB3,ZNF583,SNX25,ARHGAP17,ZNF780B,KIAA0040,NUP155,DCLRE1C,MRPS14,RHBDF2,SUGP1,RBL1,FASTK,UBXN2B,STK38,AP1S1,SPRYD4,SLC22A23,CHID1,SMAD4,RAD51D,SLC30A9,CMAS,UNK,NADSYN1,HMGN3,NCAPG,SCYL2,FZD6,HERC3,GTPBP3,CTSS,ORC3,RNLS,YTHDC1,ACP2,HMGN5,TUFM,RANGAP1,PNPLA8,HAGH,API5,ZFR,SEC23IP,E2F1,TMEM219,USP20,RBPJ,PDCD6IP,MAX,LUZP1,GXYLT1,ADAM10,CXXC1,TSC22D3,AP3M2,CUL1,GYG1,NANS,OAT,MYEF2,ANKRD26,PA2G4,NOL11,FIZ1,ZNF200,MARCH2,SLC26A2,SRP72,KLF10,LACTB,RFC2,CBFB,RAB2B,PRIM1,MAP3K4,HHEX,LUC7L3,RPS14,MAP4,MRPL27,BTF3,PTPDC1,NMD3,PTOV1,COX5B,DNAJC5,SCOC,DHPS,ANKH,VAV2,PRKAA1,C16orf87,GSPT2,DLGAP4,PXMP2,PRPF39,PSEN1,ZNF79,PDXDC1,VPS25,YY1AP1,C12orf10,RPN1,LHX8,ZNRF2,TPST1,DAPK1,CYC1,SOCS5,FDFT1,PIGT,EMB,WDR1,ZNF574,EXOSC9,ARID1A,PTTG1IP,FXR1,GOSR1,MAP2K2,TWISTNB,AKAP1,XRCC5,HMGN2,PI4K2A,CAT,DERL1,MTHFD2,HSPBP1,CEBPG,ARAP1,USP32,FAM83D,CABIN1,GPI,CYTIP,TP53RK,REPS2,RAB11B,UROD,SLC39A13,POMP,BCL2L1,DECR1,RALB,SIAH1,ADCY9,LPIN2,MRPS27,SOCS6,TTC3,ANKLE2,CDC123,OAF,VDAC2,EML4,ERC1,AMZ2,ANKZF1,RAD51C,DSN1,DDOST,DGCR8,SAFB,LMBR1,NCLN,BEND3,EYA2,DYNC1LI2,MANBA,SLC41A1,B4GALT5,FAM76A,TKT,CBLL1,ARGLU1,LANCL1,POFUT1,FAM8A1,HEATR5B,HLA-A,RFWD3,FUT8,BTF3L4,PTPN11,MRPL54,FEM1B,RPL19,CNN2,NDUFA3,MTX2,MSH6,PDLIM2,LONRF3,FBXO9,GUF1,RPL32,ZHX1,NDUFS5,WDR91,GPR89B,RORB,POLA2,ZNF76,COPA,UQCR10,PHRF1,HMGXB3,ABCB10,COMMD5,MAP1LC3B,DST,RAB35,GPATCH1,TCEA1,DEAF1,SNRNP200,LAP3,NCK1,VHL,SREK1,ARHGDIB,PITPNB,HSPB11,BRWD1,PPM1G,SH3GLB2,CRCP,BAZ1B,CAB39,ACBD4,STK11,CLU,CHEK2,ZSWIM3,TSTD2,MRPL13,CHPT1,DCAF5,CAPN1,UBE2D3,PPP1R12A,ZCCHC8,NACA,C19orf25,RPL15,PCSK7,EPN1,THRAP3,QSOX2,TTF1,NUP205,CHKA,DTL,MED10,ZRANB1,MCPH1,SLC12A2,ATP6V0D1,CSNK1G3,CREG1,NUDT4,VKORC1,SLTM,EVC2,KLHL15,SIAH2,SLC16A1,EHD4,SNRNP70,C11orf1,N4BP2L2,SNX27,CHMP2A,CORO7,FEZ2,PMS2,UCK2,UCK1,CLCC1,EXT2,MXD1,USP5,HNRNPA2B1,SAP130,NVL,PPP6C,CYB5R1,ZNF770,EBAG9,RNF25,PCGF6,METTL2A,HNRNPR,STAT6,HPS5,MAPK1,BRD9,TMEM33,DNAJC2,TRIP12,SHPRH,SCYL1,VPS45,MYO9B,GFM2,SPPL2A,FASTKD3,FGFR3,MZT2A,PPIG,ZDHHC13,H2AFY,NDUFS8,ATG13,ERI3,FBL,FRMD8,SLC35A1,MICAL3,B3GALT6,ELOVL5,HEMK1,TIMMDC1,HELB,PSPC1,MIER1,SCFD2,NDRG3,CDK11A,MTMR3,MEGF9,CENPT,PLOD3,RAB3IL1,ZSWIM6,RAB14,ADD1,KDM4A,MRPS15,XIAP,DHX8,GLUD1,ANKRD23,PABPC4,CDK5,CALM2,PSMD1,NEK6,NSRP1,RABGAP1L,SRSF4,FNIP2,KCNAB2,PCBP2,MLST8,PLK3,ZNF672,HSDL1,TOPORS,MCL1,PPFIA3,SMC2,ICMT,SLC50A1,STOML2,LIMK1,PRDX5,ATE1,MLYCD,ST3GAL2,FBXL3,TFDP2,E2F2,PFKP,AAAS,DDX42,SSRP1,MRPL9,STRN4,TOP2B,ZNRF3,TMED3,DDRGK1,RAVER2,GNS,INTS7,INPP5A,MCM5,PHF14,ZNF326,UBE2QL1,NAGPA,ETV3,TSPAN31,DHX29,TEX10,MAN1B1,CBFA2T2,ABCF1,RHOB,LRRC14B,DTWD1,PTPRF,SCARB2,OSBPL11,DUSP3,SLAIN1,MDH1,HEXA,RNF139,SNX14,TRERF1,UBR2,CHD1L,ACTR3,WDTC1,MYH9,NIPA2,PRKACA,SAFB2,ANKIB1,STAM,ARL6IP6,RAB21,ZKSCAN1,DDA1,NUP107,ANKRD13C,CEP63,ATF2,RBM15,DCTN1,SHOC2,PSRC1,MAP4K4,WBP2,ATP6V0A1,NUSAP1,NDUFA7,DNAJA1,TAF2,C19orf54,SEC61A1,WDR7,FUS,GEN1,LRP8,COIL,LRCH1,ZNF786,RPS2,SESTD1,TRAK1,JMJD6,SIKE1,AKT1S1,KRI1,FBXO3,ERH,NDUFB4,PPP1R8,PRDM4,GTSE1,GEMIN6,DCP1A,IMPA2,NUDC,PDPK1,TK1,TNFAIP3,GALC,ZNF512,KIAA0930,DDX39A,RPA1,ZNF862,ZNF180,KEAP1,POLE,PITX1,CAPN7,LRPPRC,PML,HMGB2,USF2,ANAPC4,DDX47,MCCC1,S1PR2,SEC16A,SSR1,LIN9,PCNA,TRMU,ETV6,PIK3R2,TXLNA,MYBL1,CCAR1,MRPL32,ABCC5,BAZ2A,PBXIP1,TLK1,EZR,LNX2,LRP5,BRCA1,PRKRA,STX16,EPB41,OPTN,SEPT1,SOCS4,QRSL1,PIEZO1,OSGEPL1,NAA60,GEMIN7,SEPHS2,LZTR1,RACGAP1,PPP3CB,B4GALT4,RLF,RAPGEF6,SNRNP25,RB1,VASP,VMP1,PPIL2,TIMELESS,AHDC1,ALDH18A1,TMEM8A,PREB,ABCC1,TRAPPC9,AACS,MEMO1,KRAS,RTF1,UBE4B,LY6E,PSMC4,GOLGA4,PALB2,SYNCRIP,PRPS2,NIPA1,TIGD2,RNF114,FOXM1,MRPL39,XAB2,SUMO2,DUSP22,RPL11,CSDE1,MDM2,CORO1A,METTL9,MINPP1,POC5,DVL2,GM2A,PSMA8,COQ10B,CPOX,PRPF3,TXNL4A,SRSF1,DNAJC10,SCAP,ZNF700,PLEKHG4B,TIMM17A,FAU,LTA4H,USP53,INTS2,CTDP1,CDT1,ARID5A,SUMF1,GGA2,CSNK1A1,AP3S1,RMI1,TFRC,PTPN2,IRF4,STARD9,SLC1A4,CWC27,SLC35B4,DDX31,ABCD1,RPAP3,CNTN5,SNX2,ZMYM5,CHCHD6,BSDC1,CDKN2AIPNL,FBXO41,KPNA4,BIRC5,TFE3,CDCA7L,PKD2,ACADM,CHMP7,SAT2,GCSH,ZNF496,TMEM109,TAP1,YTHDF3,NHLRC3,IKBIP,ELMOD2,KIFC1,DBNDD1,CYB5RL,PARPBP,CDC25B,DNMT1,NOL12,ORAI2,USO1,AKT2,NOL8,GNG7,AURKB,SLC25A5,ZFAND5,MAK16,STT3A,EIF2D,ITGB1,PTPN7,RRS1,ARRB2,RTN3,ZNF598,DDX58,WSB2,PPIB,MUT,HLA-E,NDUFA4,METTL3,CFLAR,NDUFS4,RNF121,MEX3C,HDAC7,BDH1,PCYT2,GNAI2,ANKHD1,TERF2,MORC3,KCTD20,SEPT8,DCTD,PKM,ADSS,SERTAD2,NSF,ACLY,LPCAT4,VCPIP1,PPP6R2,PPP6R3,MAP3K5,YY1,CDK2,RNF14,ZC3HAV1,ZBTB37,URB2,EIF3D,MAGED1,KLHL18,SLC25A44,AP1B1,SDHA,PAIP2,PHC2,CRKL,TERF2IP,ZNF75D,SHC1,UCHL5,NAA35,TMBIM1,CDKN2AIP,CCT2,MKLN1,HMGN4,GALK2,CDC23,SHCBP1,AP4E1,PRDM11,VEZF1,PPP2R5A,ACYP1,STAT1,PPA2,TRIM32,RHEBL1,C1orf112,TCF3,BRAP,MYNN,RAB11A,REEP5,FOXO3,MAD2L2,PIP5K1C,RBM17,MAT2B,PTEN,CENPJ,CREB1,NCOA2,PACS2,SMC4,NEK7,NET1,PARP4,TBRG4,ANAPC2,HGS,TTLL4,MFAP1,CCDC69,BRWD3,ESYT2,SKA3,NPHP4,UBE2E2,PLXNC1,ST13,ZNF107,SLC29A1,KIF2C,AGFG1,SIRT2,USP48,SNRPD3,FKBP2,EDC3,UBLCP1,ZNF804A,RAP1A,THADA,EIF4A3,AP3S2,ATG3,DPYSL2,PPP1R12C,AKR1B1,NDUFB9,TTC4,TECR,ARID4A,FGFR1OP2,TIMM50,TDP1,DPM1,FOPNL,SLC16A7,SLC25A22,WDR82,STK17B,DHX15,CHAF1A,GEMIN5,COPS6,SASS6,RPS26,PSMC1,SLC12A7,TBC1D12,TM9SF4,ZNF768,MED13L,TIA1,MEF2A,EPHX2,PITHD1,RHBDD1,NFATC3,ZNF335,YBX1,KNTC1,UBE3C,ACAD8,ZNF189,ALDH9A1,CIC,SEPT7,NAP1L1,ODF2,EXOC4,NUP62,PITPNA,KIAA1328,NAA20,PTDSS1,PDSS2,C7orf26,IMMT,ASH1L,CHERP,WDYHV1,PLAGL2,IRF3,CHKB,TWF2,PAIP1,ANKRD28,FARSA,ANKLE1,SAR1A,APOOL,PDIA6,ACSL5,AZI2,GFER,RAD54B,DAP3,TMEM41A,ZNF317,AKNA,REEP4,CBX4,KIF3B,GOLPH3L,SH2D3A,CASP6,TOR3A,SRGN,DBF4,MFSD10,CTNNBL1,YIF1B,CLDND1,TTC17,GINS1,CSNK1G2,TELO2,HMGN1,ADAM17,NASP,ASPM,PPP1R21,PRKAR1B,SYMPK,TARS,MAPK3,HLA-B,PLAA,ATAD2,ZNF330,OSBPL8,KBTBD7,PREPL |
| 7.097e-06 | -11.86 | Prpf8 (pre-mRNA processing factor 8) | protein interactions | 192159 | 52 | 22 | 17029 | 2761 |
SART1,C9orf78,SNRNP200,XAB2,SNRPB,PPIE,CRNKL1,LSM8,USP39,PRPF3,SNRPD3,DHX15,NCDN,DDX23,EFTUD2,PRPF4,AQR,RUVBL2,ECD,SNRPG,CDC5L,PRPF19 |
| 7.172e-06 | -11.85 | ribonucleotide metabolic process | biological process | GO:0009259 | 364 | 87 | 17256 | 2622 |
COX15,NDUFA5,PPCS,NDUFB6,UQCR10,UCK2,OLA1,UCK1,SLC35B2,EFL1,ADPGK,ATP6V1B2,ATP5PF,SDHA,IMPAD1,ADCY9,PPCDC,UPRT,NDUFB9,SLC26A2,ADCY7,ATP6V0A1,OGDH,NDUFA7,NDUFB1,TAZ,STOML2,HINT1,GUCY1B1,NDUFA11,COX5A,DHTKD1,UQCRH,NUDT11,PFKP,NDUFV2,COX5B,GALK1,NDUFS1,MECP2,RAB23,NDUFA4,COX4I1,CYCS,ABHD14B,ATP5F1B,NDUFS7,NDUFS4,GART,NDUFV1,NDUFA2,NDUFB4,ATIC,CTPS1,MSH2,TPST1,ATP6V0A2,NDUFS8,CYC1,NDUFA3,AMPD2,TGFB1,RHOA,GUK1,NUDT4,LDHA,ADSL,ATP5MF,PKM,PDE3B,HSPA1B,ADSS,MBIP,ATP5MC3,PARG,PRPS2,COX7A2L,ACLY,COX8A,IMPDH1,ACAT1,NDUFS5,ATP5F1A,GPI,NIPSNAP2,PGAM1,NUDT3 |
| 7.182e-06 | -11.84 | GSE13485_CTRL_VS_DAY21_YF17D_VACCINE_PBMC_UP | MSigDB lists | GSE13485_CTRL_VS_DAY21_YF17D_VACCINE_PBMC_UP | 179 | 50 | 17377 | 2626 |
NCOR2,ZBTB10,CORO7,TMEM184B,TRIM11,ADO,GNE,ARID5A,BRAP,AKT1S1,DAZAP2,XPO7,SNN,C2orf49,NAPG,ATP2A2,SAR1A,ZNF746,AKAP8,RAD23B,GLTP,TRIM8,TACC1,ATG9A,PGS1,USP42,SLC26A6,WBP2,KCTD20,MAP7D1,UHRF1BP1,USP22,MEF2D,DCLRE1C,ZDHHC3,MTMR3,PWWP2B,ZNF317,HGS,SERTAD2,SPATA2,NFIL3,PPP3R1,CEBPG,CCDC69,ZDHHC7,PITPNA,SAT2,RNF139,CAPN1 |
| 7.194e-06 | -11.84 | GO_ER_TO_GOLGI_VESICLE_MEDIATED_TRANSPORT | MSigDB lists | GO_ER_TO_GOLGI_VESICLE_MEDIATED_TRANSPORT | 160 | 46 | 17377 | 2626 |
TMED7,COPA,GORASP1,DYNLL1,COPE,DCTN2,ANK3,VTI1A,TMED3,SEC16A,COPG2,BCAP31,COPB2,ANKRD28,CD59,SEC24C,RAB35,PPP6C,BCAP29,TFG,LMAN1,PPP6R1,TMED2,KDELR1,PREB,DCTN1,SPTAN1,USO1,TMEM115,TRAPPC9,GOPC,CUL3,COG1,MCFD2,RAB1A,GOSR1,ARF4,SEC31A,SEC23IP,GOLGA2,NSF,TMED10,PPP6R3,NRBP1,CSNK1D,DYNC1LI2 |
| 7.245e-06 | -11.84 | microtubule cytoskeleton organization | biological process | GO:0000226 | 454 | 104 | 17256 | 2622 |
BCCIP,ZNF207,FGFR1OP,NDC1,ATXN3,POC1A,XIAP,TPX2,MYH9,NUF2,CNTROB,KIF2C,CCNB1,STMN1,BIRC2,KIFC1,CDK5,NEK6,ABRAXAS2,PIN1,KIF14,DNAAF2,XRCC2,RNF19A,CEP63,TACC3,DCTN1,CHP1,PLK1,PLK3,PSRC1,BIRC3,FOPNL,INTS13,TUBGCP5,EZR,NUSAP1,BICD2,AURKB,BRCA1,EML4,KIF2A,KIF18B,CHD3,GOLGA8A,E2F4,AXIN1,MAP4,CHEK2,DVL1,VPS4A,SASS6,CSNK1D,TUBB,DYNC1LI2,PARD3,KIF3B,MZT1,PPP1R12A,MECP2,DCTN2,CIB1,DNAAF5,KIF23,HAUS4,RACGAP1,SPDL1,RAB11A,HAUS2,TUBGCP2,SPAG5,SAPCD2,LMNA,FBXO5,STARD9,CCP110,CENPJ,PRC1,ARHGEF2,MCPH1,GCC2,RHOA,TACC1,ASPM,NEK7,CAMSAP1,MYBL2,MAP7D1,KIF11,MARK2,HAUS8,KIF18A,PCM1,GOLGA2,BIRC5,ODF2,CCDC69,SLC16A1,NUP62,PKD2,NDE1,WDR62,CDK2,ESPL1 |
| 7.272e-06 | -11.83 | negative regulation of G1/S transition of mitotic cell cycle | biological process | GO:2000134 | 118 | 37 | 17256 | 2622 |
CDK2AP2,CCNB1,CNOT11,CDC73,CNOT3,RFWD3,RPA2,RB1,PCNA,MDM2,PTEN,CENPJ,FBXO7,GTSE1,BRD7,CDKN1B,BCL2,CNOT6L,CTDSP2,CARM1,PLK3,PRKDC,BTG2,SOX4,PRMT2,CNOT9,RBL1,RPS27A,E2F4,TFDP1,PML,E2F1,CNOT6,PKD2,CHEK2,TFDP2,CDK2 |
| 7.308e-06 | -11.83 | RPL35 (ribosomal protein L35) | protein interactions | 11224 | 124 | 40 | 17029 | 2761 |
COX15,RPS2,MAX,CYLD,RPLP2,EIF3D,PRKAA1,RPL15,CUL1,SND1,RPL11,RPL23A,RPN1,RPL17,ZNF746,RPL19,TARDBP,PABPC1,RNPS1,CUL3,RPL8,RPL38,RPL6,RPS10,RPS24,BRCA1,VDAC1,RPL27A,PRPSAP1,RPS9,RPSA,CAND1,RPL36,TXNDC16,RPS14,RRS1,CDK2,ARRB2,CD81,RPS26 |
| 7.327e-06 | -11.82 | BAELDE_DIABETIC_NEPHROPATHY_DN | MSigDB lists | BAELDE_DIABETIC_NEPHROPATHY_DN | 419 | 97 | 17377 | 2626 |
TOMM20,UGP2,AGRN,UBR2,TSC22D3,CAST,ACTR3,KIAA0232,TMX4,TAP1,MYH9,GYG1,BIRC2,DST,DLG5,RAB21,NAPG,PSMA6,SP100,ATP2A2,IARS,RABGAP1L,ATP13A3,RAD23B,SEPT11,RPN2,F2R,ABI1,BIRC3,EID1,TLK1,GMFB,ATXN1,MCL1,DNAJA1,RAB1A,PSMB9,ODC1,RHEB,OPTN,DPYSL3,GLOD4,DDX17,ALDH3B1,TRAM2,HSPB11,TMED10,CHD3,CERS6,LUC7L3,STAT1,PTPN7,RBMS1,PARD3,SEC61G,MECP2,GNE,SDC2,LETMD1,TOP2B,PAWR,HMGN3,LANCL1,ITGB5,DNAJB9,CFLAR,KIF5B,CAPN2,SUB1,NFATC3,ADD3,PTPN11,MSH2,CITED2,MTX2,MORC3,HMGN1,GALC,TSPYL4,NEK7,DCAF8,ACSL3,DCTD,ISG15,XRCC5,FBXO21,MTHFD2,UAP1,CCDC6,MEGF9,YWHAZ,ACADM,PREPL,RBBP4,PDLIM5,TOB1,ZC3HAV1 |
| 7.350e-06 | -11.82 | KAT2B (lysine acetyltransferase 2B) | protein interactions | 8850 | 195 | 56 | 17029 | 2761 |
UBE2D3,MAPRE1,ATXN3,TCF3,CDT1,RBM8A,KLF13,SIRT2,TAF6L,WDR5,MAPK14,ETS1,RAB11A,TTF1,RB1,USF1,MDM2,CCNA2,PTEN,CDKN1B,TAF5L,CDC25B,TACC3,CARM1,KLF10,VHL,MEF2D,KIF11,POLR2A,IRF5,HMGN2,DDX17,UBTF,MBIP,SERTAD2,SMAD2,CDCA4,HSPA4,HIPK2,ARNTL,ACLY,SIAH2,E2F1,H2AFX,ACTB,CHEK2,RBPJ,TAF12,NCOA1,YY1,H3F3A,SMAD1,CDK2,SAT2,SGF29,CDKN2A |
| 7.374e-06 | -11.82 | HSPD1 (heat shock protein family D (Hsp60) member 1) | protein interactions | 3329 | 289 | 76 | 17029 | 2761 |
PTMS,CYLD,SARNP,RAF1,CUL1,PRKACA,MAPK14,APP,BCAT2,PRNP,HNRNPA2B1,NUDT19,TRMU,RPAP1,CRY2,ATF2,MRM2,CDC5L,BAK1,CDKN2AIP,SEPT9,CUL3,AURKB,BRCA1,MCM2,TAZ,RAB5B,FOXRED1,GLOD4,DDX17,HSPA4,ITGB1,XRCC3,FUS,CLU,SMURF1,DCAF5,SLC25A39,PARD3,SLC25A33,UNK,GORASP1,STRN4,SLC25A43,CDC73,HMG20A,NDUFS7,PTPN2,C12orf10,RFWD3,GSTK1,PTEN,HUWE1,AHSA1,FBXO7,MCPH1,PPA1,NSUN4,NIPSNAP1,EIF5A,GID8,FTL,STAU1,GBA,KRAS,MRPL16,ADRB2,SF3A2,ISG15,CAND1,SCARB2,MAPK6,PLOD3,CDK2,NIPSNAP2,ACSF2 |
| 7.407e-06 | -11.81 | DUSP22 (dual specificity phosphatase 22) | protein interactions | 56940 | 103 | 35 | 17029 | 2761 |
RAB14,TMUB1,SCAMP3,TMX3,ARFIP2,ARF1,IKBIP,DUSP22,RAP1A,INPP5A,ARF5,FBXO7,TAGLN2,GNAI2,C12orf75,CSNK1G3,TMX1,CHP1,MOSPD1,WDR18,MCL1,KRAS,TOMM40,RPL27A,STX16,ARF4,CHCHD3,SNAP23,TIMM17A,LAMTOR4,PGRMC1,CANT1,HRAS,APOL2,SVIP |
| 7.423e-06 | -11.81 | bladder | COSMIC cancer mutations | bladder | 14512 | 2234 | 17385 | 2587 |
HECA,ZBTB10,ABCC10,HEXB,TGOLN2,CCNL2,FBXO22,EEF2K,THAP4,RAD23B,ATP13A3,DNM2,FTSJ3,USP34,CCDC57,ERCC1,NRAS,EHMT1,KIF15,HNRNPF,WDHD1,MIER2,DIDO1,MCM2,RAB22A,MID1IP1,SMAD2,RPS27A,MYO18A,OGT,COX5A,SMAD1,ZNF75A,ANXA11,SLC25A33,GGA1,CCZ1,MUM1,TRIO,CUTA,RAB23,HAUS4,EIF2AK4,APH1B,PARN,CDC73,MYL6B,ATG4A,TMEM179B,PDXP,SMC3,GEMIN4,MVP,PABPC1,NUP85,PPP6R1,PPA1,IFRD1,AGGF1,RBM42,FOXK1,GTPBP4,MAP7D1,MRPL16,ELK1,EIF4H,RDH11,MAGED2,KPNA1,ETS2,TYW5,RUFY3,PDLIM5,ACSF2,EXOC3,RHOG,C5orf30,STARD7,SLC35B2,INO80E,LCLAT1,RCOR3,CPNE3,KIAA1147,AHCTF1,ZNF420,TBC1D22A,TBC1D14,GMEB1,NSFL1C,SEPT11,GPD1L,ZC3H3,ARL5A,PDCL3,SNX8,IDH3A,POLR2D,HTATIP2,TMEM147,MEF2D,TANC1,MAT2A,VPS26B,CORO1C,NSMCE2,CAMKMT,PPP5C,PITRM1,TUBB,ZNF445,SRSF6,CCM2,HABP4,FLOT1,BTN3A1,ATG2B,PPP1R3B,ZBTB45,HUWE1,ZNF260,ANXA5,LTN1,UBE3B,NAP1L4,ST8SIA2,ZNF710,RPL22L1,MED22,SPTAN1,STAU1,TCTEX1D2,DDX24,TACC1,MRS2,LDHA,RAB3IP,PICALM,TTC33,SH3BP5,SLC19A1,ACOX1,FAM3C,AEN,PARP10,YWHAH,THAP5,GPATCH4,FAM129A,TRIM11,YTHDC2,RBM8A,SNX15,NENF,SND1,RUFY1,TRIM65,ZER1,KRR1,RAB8A,NUP210,NT5DC1,NOC2L,TACC3,VPS13B,PTPN18,MIOS,MBLAC2,SNRPB,CDC6,PBRM1,UTP3,ODC1,USP21,TRAM2,FBXO28,BCL7C,ARRDC1,ADAM9,DVL1,NUMB,ZNF564,FUBP1,CTU2,PARP12,ZCCHC9,CENPF,LAMTOR3,NCKAP1,RSAD1,TNS3,RINL,MBD2,SSBP3,KIF13B,XPA,AHCY,RBM3,GLE1,LRSAM1,NTPCR,NSDHL,CAMSAP1,ZNF761,METTL22,ICAM2,APPL1,BBS12,ANKRD46,RXRB,SDHB,PCM1,GALNT2,TMEM168,NLRC5,RUVBL2,BTBD10,MYO9A,CCNB2,USP7,GLT8D1,RPLP2,SUCLG1,ARID2,TMX4,SLC2A1,LYN,PCBP1,BCAP31,MRPL50,VAV1,TMEM69,PSMA6,ZNF473,BRPF3,ZNF302,TARDBP,BCAP29,PRPF19,KDM3B,MND1,CLCN3,BIRC3,RAB7A,ANKRD33B,PPIE,CHMP2B,VDAC1,TMEM201,EIF3H,IDE,DHX16,UHRF2,XRCC3,PARD3,BCL2L12,MCM10,PDAP1,TMX3,CDCA8,GTF3A,ARF1,SLC12A9,TUBGCP2,DNAJB9,HOMER1,POLR1B,RNF5,RBM15B,PPAN,RHOA,RPRD1A,BTAF1,TOP3A,ARHGEF12,PCGF1,DDX23,RAB18,CACNB1,TRIM26,PDCD6,ATP6V1D,L3MBTL3,FAM110A,NEIL3,BBX,IMPDH1,TAF12,NR2F2,PGAM1,HIPK3,IFI16,NUP188,PNISR,PRKCSH,USP39,UBE2I,PARK7,SLC25A37,ASPHD2,ZNF428,RAB4A,TRA2B,SUCLG2,TAF5L,CISD2,SMARCE1,ZNF800,CDC5L,ZNF524,SGCE,OSBP2,NSUN2,USP22,EIF3A,ZMYM3,DOT1L,IWS1,ANKRD10,WAS,KIF18B,TPP2,ZMAT3,B4GALT2,PRPF38B,RECQL,C9orf78,EWSR1,GADD45G,RRM1,ACAP1,B4GALT1,CYCS,SUPT7L,TMEM165,WDR48,CNOT3,NPLOC4,RTKN,CEP104,EXOSC7,KLHL5,LRRC8D,PPP4R1,MSH2,PIGG,FBXL7,OSTF1,MRPL40,TNRC18,SYTL3,FAM171A1,APOL1,EIF5A,GCC2,PRIM2,RDH10,MFNG,GORASP2,CAPZA2,ADRB2,MTR,CCT8,PHF6,SLCO4A1,PFDN5,TTC13,GOLGA2,RBMX,MED15,PIAS2,APPL2,CDKN2A,ZNF511,ATXN3,RAF1,KIAA0232,C2orf49,EPM2A,CCNA2,MTMR4,BRI3,AQR,TP53BP2,RBM12B,CDK12,ILKAP,SAP30,BRD4,NARF,LRRC8A,ELP4,ABHD11,PKMYT1,ASB13,TRIM28,SUPT16H,EIF3K,CHMP4A,ATF6,XRCC4,ADAM23,PRPF4B,NDUFS1,DEPDC1,MECP2,SECISBP2,HMG20A,WWP2,SLC25A36,JAKMIP1,CCNK,AXIN2,CITED2,JMJD4,KAT2A,ANKRD37,RABIF,ADSL,PACS1,BMS1,KCNQ1,OTUD3,ARSK,MACF1,KLF6,COMMD4,KIF11,FADD,SH3GLB1,SMAP2,MYO1F,CBX3,INF2,PPP1R11,DUSP11,DDX5,WDR62,TAF6,ESPL1,PURA,DEF6,FAM83G,IPO4,DDB1,UBL3,PIGM,NAT9,PTP4A3,UBE2Q1,BRIX1,MRPL19,ZNF696,SF3B2,PCYOX1L,CDC42,SYNM,GOT2,JAZF1,HADHB,RPF2,SLC35C2,CNNM3,CARM1,SRPK2,WDR41,LARS,CCDC138,LRBA,TMEM216,SUMF2,KMT2C,OGFR,PRPSAP1,ASF1B,RPL37,MAN2A2,EIF4ENIF1,NIP7,U2SURP,MIA2,VPS4A,ATP6V0E1,PPP1R2,XPNPEP3,RGS2,LYAR,FAM89B,POLR2I,TRAFD1,SUGP2,GBA,SYVN1,DAPK3,ARHGAP15,MASTL,UAP1,NFIL3,FN3KRP,YWHAZ,CTSA,TOB1,ADNP2,TCF12,PRKAB1,MDH2,SMARCA4,ORC1,RRN3,UBXN2A,IARS,CD3EAP,KIF14,EXOSC1,CS,CLTB,DNAL4,POU2AF1,UBQLN4,SELPLG,ATXN1,GLO1,BICD2,OGDH,CADM1,EDEM2,HERPUD2,TOLLIP,FANCE,MBD3,RPS9,PDHX,ARNTL,ANP32E,FKBP5,TMEM101,CCDC125,ABCA1,PDCD2L,GCLM,RAE1,DCTN2,NUP54,CHIC2,PAWR,MXD4,DCUN1D4,PIP4K2A,XPR1,FERMT3,KIF5B,KLHL20,SEC24C,RRBP1,ARHGEF2,ANP32A,LDLRAD3,STAT3,MYO5A,NIPAL3,AMPD2,TXNL1,PHF20L1,DCAF6,FAM49B,TMEM39A,ATP2C1,RFFL,COG1,RCOR1,PRMT2,TFEB,LEMD2,SERF1B,UPF1,ELMO1,ZC3H7B,DTX4,ZMIZ1,HRAS,TERF1,CCDC93,TMED7,FGFR1OP,PIGQ,AGPAT1,CNTROB,PPP1R16B,GSDMB,TTC9C,PDS5B,NUP153,SENP1,PGAP2,TMEM115,PLEKHM3,PLEKHF2,BRMS1,TRIM47,PWWP2B,WDR11,AXIN1,SMG9,LONP2,NDUFV2,CERK,SLC4A2,EZH1,ITGB5,LMNA,MCTS1,DDX56,EIF2S2,SLC38A5,FOXN2,CARS2,RB1CC1,C16orf72,PRRC2A,ZMYND11,PGS1,MYBL2,UHRF1BP1,SRSF5,MPG,MATR3,CYB5A,SETD3,TEX30,PTAR1,CNOT6,NDE1,EGLN1,ZNF207,ANKRD27,ABCA3,SARNP,IVNS1ABP,TMEM97,MON1B,RMI2,NUF2,NIT2,ZNF267,KTN1,APP,CLUAP1,PRKD3,ATP2A2,UTP18,GRSF1,DUT,ZCCHC2,ANAPC7,FAM76B,RNF19A,CLN6,GCC1,RNF169,ATP6V1G1,ADCY7,ENPP4,RNPS1,CDCA2,FKBP3,DDX17,GPR137,CHCHD3,PEX5,CDC16,HIPK2,MBOAT1,TICAM1,PDXK,ZBTB11,TMBIM4,ANXA6,GMCL1,UBE4A,ETS1,IL21R,ZNF92,CAPN2,ADD3,SUV39H2,TTLL12,TPCN1,HNRNPM,TMX1,LYPLA2,MFSD12,LDHB,PPP3CA,NUDT8,POLK,MTMR12,ZP3,PDE3B,KIF18A,CCDC6,WNT5B,MAPK6,LY75,SLC25A19,RGL1,PSAP,WDR76,IGBP1,FAF1,COX15,THOC1,AGRN,PPP1R15B,CSNK2A1,EBNA1BP2,BIRC2,GIT2,ATPAF1,ABL2,DLG5,XRCC2,ZFYVE27,MCMBP,PTPRK,CDC37,METTL1,SP3,HARS,GMFB,ESYT1,ANLN,RAB5B,RHEB,DPYSL3,TBC1D17,CDCA4,TIMM13,TONSL,NRM,NAGLU,ACTB,ZNF45,TMUB1,CTCF,ASAH1,DOCK11,ASXL2,CRLF3,LRRC14,NUS1,SLC27A4,MDFIC,AFF1,MAML1,CYTH1,NQO2,UTP15,EIF2AK1,EIF4G2,ZDHHC3,MOSPD3,ITPRIPL1,CDC27,SNAP23,TBPL1,PRMT7,KCTD7,NDUFA5,UGP2,DYNLL1,COPE,HCFC1R1,ZADH2,GGPS1,RPAIN,RAD23A,ATP6V0B,PDK2,STRBP,MRPL34,PDCD2,SAP30L,CLPTM1,RPL35,BTG2,DNAJC9,MTMR6,NFATC2,KDM1B,ARL5B,USP36,ATP1A1,CLK3,MAFK,PSMD3,CEP55,ZNF436,DNAJC17,NCOA1,SLC25A39,ZC3HC1,ZNF146,ATXN7L2,SMAP1,GOLIM4,CDC40,GNE,SMC6,ARFIP2,NKRF,CHAC2,BZW2,WRNIP1,SS18L1,CAMK2G,MLEC,ZNF202,PPWD1,FAM50B,RHOT2,TPD52L2,GOLGA7,TWSG1,PGRMC1,GLG1,FAM126A,UBE2C,RPS6KC1,PPCS,NDUFB6,TMEM41B,PLXNA1,CCNB1,COMMD6,SLC20A1,POLR3K,C14orf119,SNUPN,ASAP2,CNPY4,PLCL2,TFG,SEH1L,ATG9A,PBK,MKI67,DDX20,GALNT7,SLC17A5,AMDHD2,CCNF,FOXRED1,RBM47,WDR4,DHTKD1,TRAF5,HDAC2,PWWP2A,HSPH1,MAPRE1,CHTF18,KIF23,SLC35B1,PMF1,NOTCH2,JMY,FKBP1A,SNX18,ATIC,CTPS1,ATP6V0A2,RNF135,PIKFYVE,LPCAT1,EEF1D,TMED2,FTL,PHF10,DDX28,ZNF84,SIGMAR1,PIP4K2C,PLEC,RIT1,KDM3A,FAS,EPRS,ZNF777,TMEM54,QARS,PPP3R1,TCOF1,NRBP1,CABLES1,DNMT3A,CKLF,RWDD1,TRIP10,RPS6KA1,SF3B1,SUZ12,CAST,GPR89A,RAC1,OLA1,SNN,GNB2,FLAD1,APLP2,KDM2A,TNPO2,CDKN1B,TALDO1,ATP13A1,MAPRE2,RFC3,ERF,CUL3,SLBP,KIAA1586,POLG2,PSMB9,H2AFV,GAR1,DHX57,NSA2,HSPA4,JAK1,TBL3,GOLGA8A,H2AFX,SEL1L,KLHDC4,PDCD11,ATMIN,POLQ,OTUD5,NCOR2,ANKRD13D,PKP4,SCAMP3,BABAM1,CDCA3,SLC25A12,BLM,GTF2F1,TMCC3,CRAT,AHSA1,PRC1,UPF2,SLC38A10,COPS7B,CNOT6L,CNPY3,IFT46,UBE2M,TSHZ1,ZFP64,STRIP1,DENND1B,DENND4C,ILF3,LRRC1,RHOT1,TSR2,MARK2,PRDX1,NUCB1,FBXO21,GNA12,PLD3,C1orf131,PFDN4,PRDX3,HNRNPH3,STX18,TFDP1,KHSRP,ASNA1,VPS29,S100PBP,MIB2,IER2,NOP2,UBN1,NF1,DCAF15,ALKBH5,MOGS,TAF6L,MAPK14,BECN1,SNAPC4,RNF103,BCAT2,MBD4,METTL14,IMPAD1,ZNHIT6,RCSD1,PHTF1,KIF22,ZBTB22,OGG1,TRIM14,COPS8,FYTTD1,TRIM8,RRM2,SOX4,ABHD5,PAF1,CXXC4,UBTF,SPATA2,UEVLD,ATXN2L,PQBP1,IARS2,RPS15,PIGN,AGTRAP,CIB1,XPO7,SRRT,ZNF449,CAPZA1,BCL2,KIFAP3,GLTP,N4BP2,HP1BP3,THNSL1,CAND1,GNAS,TSC1,RBM25,CDCA5,ZFP90,RBBP4,ZBTB24,SMARCD1,WASF2,MBD1,MMACHC,TOMM20,MPHOSPH8,GNPNAT1,HNRNPUL2,CHD1,C2orf68,CCDC50,AKAP8,PARL,RPN2,CHTOP,FAM3A,F2R,ABI1,SCYL3,TMEM14C,HTRA2,RLIM,MOSPD1,FAM172A,ZNF500,NLN,WIPF1,BOLA1,NDUFB1,BUD13,PEF1,EIF3G,BTBD1,TAB2,TULP3,CHCHD1,WDR59,CANT1,SCARB1,GAS2,USP11,SMURF1,TSPAN5,PPP2R2D,CDS2,MAGEH1,EYA1,CDK2AP2,LETMD1,KLF13,HDDC2,RGS1,MAN1A1,FBXO5,GART,PELO,TANK,BRD7,MRPL11,SAMD4B,WDR81,MEN1,ZNF407,MFN2,COX8A,ZRANB2,SRSF3,MBD6,ATP6V1C1,TATDN1,IDH3B,TSC2,LACTB2,RBM4,ZNF275,ANKRD39,RPL23A,CDKN2C,USF1,NAPG,DNAAF2,AP1M1,MECR,UPRT,CRY2,ECD,MOB1A,RNF26,LRRC59,TIPARP,BAK1,RHOBTB3,ZNF559,GABPA,NUTF2,WBP1,ARF4,KRIT1,BOLA3,AHNAK,RAD18,RNASEL,CHPF2,PDCD4,NXT2,HIVEP3,KIAA0100,CLSPN,RHOC,DHX9,PDCD7,PSMD9,COPB2,TFAP4,CD59,RNFT1,MEGF8,RIMS3,FBXO7,EFTUD2,CPSF4,MRPL21,PHKG2,LUC7L2,SRSF11,EIF3L,MTA2,TYW1,SSR2,USP10,ITM2A,BCLAF1,MTX1,SFXN5,FNTA,TXNDC16,ZNF830,TMEM159,MRPL3,ALS2,TRIM41,KARS,POC1A,ANK3,PTTG1,TPX2,TBC1D13,DAZAP2,GLRX3,STMN1,C19orf48,REPS1,ABHD16A,FBXL6,SH3BP1,MTA1,UBA5,CLCN6,INTS12,RPRD1B,CGGBP1,CPNE1,FAM118B,GOPC,E2F3,CIRBP,CRNKL1,PFKFB3,GORAB,RAB1A,GIGYF1,KIF2A,PPP2CA,LSM6,CCDC14,RNF38,SNRPG,DMWD,USP13,ZFP91,TRMT6,IP6K2,SLC25A43,IFT27,PMVK,NEIL2,RRP36,SRXN1,RPA2,PSMD2,CLIC4,PDCD10,CBWD2,COQ4,ITGB8,ARF5,ARHGEF1,GTF2H2,FBXL19,TTPAL,UTP20,MAGT1,GPS2,DBI,SSNA1,MRFAP1L1,CD81,TMEM131,WDR13,FANCI,CREM,PAPOLA,TET3,FANCL,GLIS2,INTS1,IL6ST,ASB6,RPP25,PLK1,CELSR2,SEPT9,APH1A,RBX1,RAD51AP1,PSMG1,UBE2V1,EAF2,KRTCAP2,LUC7L,LSG1,NECAP2,TRIM4,AGPAT2,CHD3,E2F4,KPNA2,PRPF4,BEND6,CLN3,DNAJC30,NGLY1,FAM208A,POT1,RMND5A,HJURP,PHB2,DNAJB2,FAM53C,NKD2,KLC1,CDK13,ADCK5,COX4I1,DNAJB1,RAB6A,ARID1B,C1GALT1,UBE2Q2,MLX,CCP110,ZNF746,CTR9,NIPSNAP1,ABHD2,DCAF8,LDB1,ACSL3,MAP4K3,ARMC8,NMT2,IRF5,RPL36,HAUS8,MBIP,ORMDL2,COX7A2L,SIL1,FAM122A,ZDHHC7,UNC13C,BCCIP,SART1,TRAF7,TOR1AIP1,LAGE3,TM9SF3,ZNF121,OIP5,NRF1,WDR44,PPME1,PIN1,EFCAB11,RPAP1,CABLES2,AHCYL1,TOP1MT,LMAN1,STRAP,ZNF583,SPSB3,SNX25,ARHGAP17,ZNF780B,NUP155,DCLRE1C,MRPS14,RHBDF2,SUGP1,RBL1,STK38,FASTK,UBXN2B,AP1S1,SLC22A23,H3F3A,SMAD4,RAD51D,SLC30A9,CMAS,UNK,NADSYN1,HMGN3,NCAPG,SCYL2,FZD6,HERC3,GTPBP3,CTSS,ORC3,RNLS,YTHDC1,ACP2,HMGN5,CSRP1,ABCF2,METTL5,TUFM,RANGAP1,API5,HAGH,ZFR,SEC23IP,E2F1,USP20,RBPJ,PDCD6IP,MAX,LUZP1,GXYLT1,ADAM10,CXXC1,TSC22D3,AP3M2,CUL1,NANS,MYEF2,ANKRD26,PA2G4,NOL11,FIZ1,ZNF200,MARCH2,SLC26A2,SRP72,KLF10,LACTB,CBFB,RFC2,RAB2B,MAP3K4,HHEX,MAP4,MRPL27,PTPDC1,BTF3,NMD3,PTOV1,COX5B,DNAJC5,DHPS,C16orf87,PRKAA1,VAV2,GSPT2,ANKH,TATDN3,DLGAP4,PXMP2,PSEN1,ZNF79,VPS25,PDXDC1,NDUFS7,YY1AP1,FAM192A,RPN1,LHX8,ARPC5,TPST1,DAPK1,CYC1,PIK3IP1,SOCS5,PIGT,EMB,WDR1,ZNF574,C1orf35,EXOSC9,ARID1A,FXR1,GOSR1,MAP2K2,TWISTNB,AKAP1,HMGN2,XRCC5,PI4K2A,DERL1,CAT,HSPBP1,MTHFD2,ARAP1,USP32,FAM83D,CABIN1,SMPD4,GPI,CYTIP,TP53RK,REPS2,RAB11B,UROD,SLC39A13,BCL2L1,NUDT19,DECR1,SIAH1,RALB,LPIN2,ADCY9,SOCS6,TTC3,ANKLE2,OAF,VDAC2,EDF1,EML4,ERC1,ANKZF1,RAD51C,ZNF282,DSN1,HINT1,DGCR8,SAFB,HAGHL,FTSJ1,RWDD4,NCLN,BEND3,EYA2,DYNC1LI2,MANBA,SLC41A1,FAM76A,TKT,CBLL1,ARGLU1,POFUT1,FAM8A1,HEATR5B,HLA-A,EBP,RFWD3,FUT8,FJX1,PTPN11,BTF3L4,MRPL54,FEM1B,CNN2,MTX2,MSH6,PDLIM2,LONRF3,RFXANK,FBXO9,GUF1,RPL32,ZHX1,OAZ2,WDR91,HIGD2A,GPR89B,RORB,POLA2,ZNF76,MTX3,COPA,PHRF1,DST,RAB35,SIVA1,GPATCH1,TCEA1,DRAM2,TRAPPC13,SNRNP200,LAP3,NCK1,VHL,SREK1,ARHGDIB,PITPNB,HSPB11,BRWD1,PPM1G,SH3GLB2,BAZ1B,ACBD4,CAB39,STK11,CHEK2,CLU,CHPT1,MRPL13,TSTD2,DCAF5,CAPN1,UBE2D3,PPP1R12A,GORASP1,ZCCHC8,NACA,C19orf25,RPL15,PCSK7,EPN1,THRAP3,TTF1,QSOX2,NUP205,PRPF18,CHKA,DTL,MED10,ZRANB1,MCPH1,SLC12A2,ATP6V0D1,CSNK1G3,NUDT4,RPL6,VKORC1,SLTM,EVC2,KLHL15,SIAH2,SLC16A1,SNRNP70,EHD4,C11orf1,APOL2,N4BP2L2,CHMP2A,SNX27,CORO7,FEZ2,PMS2,UCK2,CLCC1,EXT2,MXD1,USP5,HNRNPA2B1,SAP130,NVL,PPP6C,CYB5R1,ZNF770,EBAG9,RNF25,METTL2A,PCGF6,PON2,HNRNPR,HPS5,STAT6,BRD9,MAPK1,TMEM33,DNAJC2,TRIP12,SHPRH,SCYL1,MYO9B,GFM2,SPPL2A,FASTKD3,FGFR3,PPIG,TMEM99,H2AFY,NDUFS8,ATG13,ERI3,FBL,SLC35A1,FRMD8,MICAL3,ELOVL5,TIMMDC1,PSPC1,HELB,MIER1,SCFD2,NDRG3,CDK11A,MTMR3,MEGF9,ACAT1,CENPT,PLOD3,RAB3IL1,RAB14,ADD1,MRPS15,KDM4A,XIAP,DHX8,GLUD1,PABPC4,CALM2,CDK5,PSMD1,NEK6,NSRP1,RABGAP1L,SRSF4,PCBP2,KCNAB2,MLST8,PLK3,ZNF672,MRPL43,HSDL1,MCL1,TOPORS,PPFIA3,SMC2,ICMT,SLC50A1,STOML2,ZNF689,LIMK1,PRDX5,ATE1,MLYCD,FBXL3,TFDP2,E2F2,PFKP,SSRP1,DDX42,MRPL9,MRPS2,STRN4,TOP2B,ZNRF3,DDRGK1,RAVER2,GNS,INPP5A,INTS7,MCM5,PHF14,NAGPA,TIMM8B,ETV3,DHX29,TEX10,MAN1B1,CBFA2T2,ABCF1,RHOB,LRRC14B,PTPRF,DTWD1,SCARB2,OSBPL11,CCDC86,DUSP3,MDH1,HEXA,RNF139,SNX14,ZNF296,TRERF1,UBR2,ACTR3,CHD1L,WDTC1,MYH9,CREBL2,NIPA2,SAFB2,PRKACA,STAM,ANKIB1,ARL6IP6,RAB21,SP100,ZKSCAN1,DDA1,NUP107,ANKRD13C,MAVS,CEP63,RBM15,ATF2,DCTN1,SHOC2,PSRC1,MAP4K4,ATP6V0A1,NUSAP1,NDUFA7,DNAJA1,TAZ,TAF2,C19orf54,RPLP1,WDR7,CBLN2,FUS,GEN1,LRP8,COIL,LRCH1,ZNF786,GALK1,RPS2,SESTD1,TRAK1,JMJD6,SIKE1,AKT1S1,KRI1,FBXO3,ERH,GATC,NDUFB4,PPP1R8,PRDM4,DCP1A,GEMIN6,GTSE1,SGCB,S100A6,IMPA2,NUDC,PDPK1,TK1,TNFAIP3,GALC,ZNF512,KIAA0930,MRPS10,DDX39A,RPA1,ZNF180,ZNF862,KEAP1,POLE,TATDN2,PITX1,CAPN7,PML,LRPPRC,HMGB2,USF2,ANAPC4,SRM,DDX47,MCCC1,S1PR2,SEC16A,SSR1,LIN9,PCNA,ZNF639,ETV6,PIK3R2,TXLNA,PPCDC,MYBL1,CCAR1,MRPL32,ABCC5,BAZ2A,PBXIP1,TLK1,MRPL12,LNX2,EZR,LRP5,BRCA1,PRKRA,STX16,OPTN,EPB41,SEPT1,SOCS4,QRSL1,OSGEPL1,GLCCI1,NUDT11,GEMIN7,LZTR1,RACGAP1,PPP3CB,B4GALT4,RLF,RAPGEF6,RB1,VMP1,PPIL2,MEA1,TIMELESS,AHDC1,TMEM8A,ALDH18A1,PREB,ABCC1,TRAPPC9,AACS,MEMO1,RTF1,KRAS,UBE4B,NFATC2IP,ARPC1A,ZNF174,PSMC4,GOLGA4,PALB2,PRPS2,NIPA1,TIGD2,RNF114,FOXM1,XAB2,MRPL39,SUMO2,DUSP22,COMMD8,RPL11,CSDE1,MDM2,CORO1A,MINPP1,DVL2,POC5,PSMA8,TIGD5,SLC26A6,CYP20A1,PRPF3,RPSA,SRSF1,DNAJC10,SCAP,ZNF700,PLEKHG4B,TIMM17A,FAU,LTA4H,AP2S1,USP53,INTS2,CTDP1,MIF4GD,CDT1,ARID5A,SUMF1,GGA2,CSNK1A1,RMI1,TFRC,PTPN2,STARD9,IRF4,NDUFV1,SLC1A4,CWC27,SLC35B4,DDX31,ABCD1,RPAP3,CNTN5,SNX2,ZMYM5,CCDC34,CHCHD6,BSDC1,CDKN2AIPNL,FBXO41,KPNA4,BIRC5,TFE3,SNAP29,CDCA7L,PKD2,CHMP7,SAT2,ZNF496,TAP1,NHLRC3,IKBIP,EIF1B,KIFC1,DBNDD1,CYB5RL,PARPBP,CDC25B,DNMT1,NOL12,ORAI2,USO1,AKT2,NOL8,GNG7,AURKB,MCFD2,SLC25A5,ZFAND5,MAK16,STT3A,EIF2D,PTPN7,ITGB1,UQCRH,RRS1,ARRB2,RTN3,ZNF598,DDX58,WSB2,PPIB,MUT,HLA-E,NDUFA4,MAN2B1,METTL3,CFLAR,RNF121,MEX3C,KLF16,DAD1,HDAC7,BDH1,PCYT2,GNAI2,ANKHD1,TERF2,MORC3,SEPT8,KCTD20,DCTD,TOMM40,PKM,PATL1,ADSS,SERTAD2,NSF,ZFP92,DCK,ACLY,VCPIP1,MAP3K5,PPP6R2,PPP6R3,YY1,CDK2,RNF14,ZC3HAV1,SYS1,ZBTB37,URB2,MAGED1,KLHL18,SLC25A44,AP1B1,SDHA,PAIP2,PHC2,TERF2IP,MOAP1,CRKL,CYHR1,ZNF75D,SHC1,UCHL5,NAA35,CDKN2AIP,CCT2,MKLN1,HMGN4,GALK2,CDC23,SHCBP1,AP4E1,PRDM11,VEZF1,PPP2R5A,ACYP1,STAT1,PPA2,TRIM32,RHEBL1,R3HCC1L,MRI1,TCF3,BRAP,MYNN,AGPAT3,SPR,RAB11A,REEP5,FOXO3,MAD2L2,CCDC28A,PIP5K1C,MAT2B,RBM17,PTEN,CENPJ,NCOA2,PACS2,SMC4,NET1,NEK7,PARP4,TBRG4,ANAPC2,YIF1A,SGSH,HGS,TTLL4,MFAP1,CCDC69,BRWD3,ESYT2,NPHP4,UBE2E2,SKA3,PLXNC1,ST13,HNRNPAB,DNAJC24,ZNF107,SIRT2,AGFG1,SLC29A1,KIF2C,UBQLN2,USP48,FKBP2,CUTC,EDC3,ZNF804A,RAP1A,EIF4A3,THADA,AP3S2,ATG3,DPYSL2,PPP1R12C,AKR1B1,JOSD1,NDUFB9,RP2,TECR,ARID4A,TIMM50,TDP1,DPM1,FOPNL,SLC16A7,SLC25A22,WDR82,STK17B,CHAF1A,GEMIN5,COPS6,PSMC1,SLC12A7,TM9SF4,ZNF768,TIA1,MED13L,MEF2A,EPHX2,RHBDD1,NFATC3,ZNF335,BUD31,KNTC1,UBE3C,ACAD8,ALDH9A1,KDELR1,ZNF189,TSTA3,CIC,OXR1,TMEM241,NAP1L1,NSMF,ODF2,EXOC4,NUP62,PITPNA,KIAA1328,NAA20,MZT2B,PDSS2,PTDSS1,C7orf26,TMEM106C,IMMT,ASH1L,CHERP,WDYHV1,PLAGL2,CHKB,TWF2,PAIP1,ANKRD28,FARSA,ANKLE1,SAR1A,SCAMP4,APOOL,PDIA6,ACSL5,AZI2,GFER,RAD54B,DAP3,ZNF317,AKNA,REEP4,CBX4,MIF,KIF3B,GOLPH3L,SH2D3A,CASP6,TOR3A,SRGN,DBF4,MFSD10,SAC3D1,CTNNBL1,YIF1B,CLDND1,TTC17,SLC25A1,GINS1,TELO2,CSNK1G2,HMGN1,ADAM17,NASP,ASPM,PPP1R21,PRKAR1B,SYMPK,TARS,HSPA1B,MAPK3,HLA-B,PLAA,ATAD2,OSBPL8,ZNF330,KBTBD7,PREPL |
| 7.423e-06 | -11.81 | urinary_tract | COSMIC cancer mutations | urinary_tract | 14512 | 2234 | 17385 | 2587 |
HECA,ZBTB10,ABCC10,HEXB,TGOLN2,CCNL2,FBXO22,EEF2K,THAP4,RAD23B,ATP13A3,DNM2,FTSJ3,USP34,CCDC57,ERCC1,NRAS,EHMT1,KIF15,HNRNPF,WDHD1,MIER2,DIDO1,MCM2,RAB22A,SMAD2,MID1IP1,RPS27A,MYO18A,OGT,COX5A,SMAD1,ZNF75A,ANXA11,SLC25A33,GGA1,MUM1,CCZ1,TRIO,CUTA,RAB23,HAUS4,EIF2AK4,APH1B,PARN,CDC73,MYL6B,ATG4A,TMEM179B,PDXP,SMC3,GEMIN4,MVP,NUP85,PPP6R1,PABPC1,PPA1,IFRD1,AGGF1,FOXK1,RBM42,GTPBP4,MAP7D1,MRPL16,ELK1,EIF4H,RDH11,MAGED2,KPNA1,ETS2,TYW5,RUFY3,PDLIM5,ACSF2,EXOC3,RHOG,STARD7,C5orf30,INO80E,SLC35B2,RCOR3,LCLAT1,CPNE3,KIAA1147,ZNF420,AHCTF1,TBC1D22A,TBC1D14,GMEB1,NSFL1C,SEPT11,GPD1L,ZC3H3,ARL5A,PDCL3,SNX8,IDH3A,POLR2D,HTATIP2,MEF2D,TMEM147,TANC1,MAT2A,VPS26B,NSMCE2,CORO1C,CAMKMT,PPP5C,PITRM1,TUBB,ZNF445,SRSF6,HABP4,CCM2,FLOT1,BTN3A1,ATG2B,PPP1R3B,ZBTB45,HUWE1,ZNF260,ANXA5,LTN1,UBE3B,NAP1L4,ZNF710,ST8SIA2,RPL22L1,MED22,SPTAN1,STAU1,DDX24,TCTEX1D2,TACC1,MRS2,LDHA,RAB3IP,TTC33,PICALM,SH3BP5,SLC19A1,ACOX1,FAM3C,AEN,PARP10,YWHAH,THAP5,GPATCH4,FAM129A,TRIM11,YTHDC2,SNX15,RBM8A,NENF,SND1,RUFY1,TRIM65,ZER1,KRR1,RAB8A,NUP210,NT5DC1,NOC2L,TACC3,VPS13B,PTPN18,MIOS,MBLAC2,SNRPB,CDC6,UTP3,PBRM1,ODC1,USP21,TRAM2,FBXO28,BCL7C,ARRDC1,ADAM9,DVL1,NUMB,ZNF564,FUBP1,CTU2,PARP12,ZCCHC9,CENPF,LAMTOR3,NCKAP1,RSAD1,TNS3,RINL,SSBP3,KIF13B,MBD2,XPA,AHCY,RBM3,GLE1,LRSAM1,NTPCR,NSDHL,CAMSAP1,ZNF761,METTL22,ICAM2,APPL1,BBS12,ANKRD46,RXRB,SDHB,PCM1,GALNT2,TMEM168,NLRC5,RUVBL2,BTBD10,MYO9A,CCNB2,USP7,GLT8D1,RPLP2,SUCLG1,ARID2,TMX4,SLC2A1,PCBP1,LYN,BCAP31,VAV1,TMEM69,MRPL50,PSMA6,ZNF473,ZNF302,BRPF3,TARDBP,BCAP29,PRPF19,KDM3B,MND1,CLCN3,BIRC3,RAB7A,ANKRD33B,PPIE,CHMP2B,VDAC1,EIF3H,TMEM201,IDE,DHX16,UHRF2,XRCC3,PARD3,BCL2L12,MCM10,PDAP1,CDCA8,TMX3,GTF3A,ARF1,SLC12A9,TUBGCP2,DNAJB9,HOMER1,POLR1B,RNF5,RBM15B,PPAN,RHOA,RPRD1A,BTAF1,TOP3A,ARHGEF12,PCGF1,DDX23,RAB18,CACNB1,TRIM26,PDCD6,ATP6V1D,L3MBTL3,FAM110A,NEIL3,BBX,IMPDH1,TAF12,NR2F2,PGAM1,HIPK3,IFI16,NUP188,PNISR,PRKCSH,USP39,UBE2I,PARK7,SLC25A37,ASPHD2,ZNF428,RAB4A,TRA2B,SUCLG2,CISD2,TAF5L,SMARCE1,ZNF800,CDC5L,ZNF524,SGCE,OSBP2,NSUN2,USP22,EIF3A,ZMYM3,DOT1L,IWS1,ANKRD10,WAS,KIF18B,TPP2,ZMAT3,B4GALT2,PRPF38B,RECQL,C9orf78,EWSR1,GADD45G,RRM1,ACAP1,B4GALT1,CYCS,SUPT7L,TMEM165,NPLOC4,CNOT3,WDR48,RTKN,CEP104,EXOSC7,KLHL5,LRRC8D,PPP4R1,MSH2,PIGG,OSTF1,FBXL7,MRPL40,TNRC18,SYTL3,FAM171A1,APOL1,EIF5A,GCC2,PRIM2,RDH10,MFNG,GORASP2,CAPZA2,ADRB2,CCT8,MTR,PHF6,PFDN5,SLCO4A1,TTC13,GOLGA2,RBMX,MED15,PIAS2,APPL2,CDKN2A,ZNF511,ATXN3,RAF1,KIAA0232,C2orf49,EPM2A,CCNA2,MTMR4,BRI3,TP53BP2,AQR,RBM12B,ILKAP,CDK12,SAP30,BRD4,NARF,LRRC8A,ELP4,ABHD11,PKMYT1,ASB13,TRIM28,SUPT16H,EIF3K,CHMP4A,ATF6,XRCC4,ADAM23,PRPF4B,NDUFS1,DEPDC1,MECP2,SECISBP2,HMG20A,WWP2,JAKMIP1,SLC25A36,CCNK,AXIN2,CITED2,JMJD4,ANKRD37,KAT2A,RABIF,ADSL,PACS1,BMS1,KCNQ1,OTUD3,ARSK,MACF1,KIF11,COMMD4,KLF6,SMAP2,FADD,SH3GLB1,MYO1F,CBX3,INF2,PPP1R11,DUSP11,DDX5,WDR62,TAF6,ESPL1,PURA,DDB1,DEF6,IPO4,FAM83G,UBL3,NAT9,PIGM,UBE2Q1,PTP4A3,BRIX1,MRPL19,ZNF696,SF3B2,PCYOX1L,CDC42,SYNM,GOT2,JAZF1,HADHB,RPF2,SLC35C2,CNNM3,CARM1,SRPK2,WDR41,LARS,CCDC138,LRBA,TMEM216,SUMF2,KMT2C,OGFR,PRPSAP1,ASF1B,RPL37,MAN2A2,EIF4ENIF1,NIP7,U2SURP,MIA2,VPS4A,ATP6V0E1,PPP1R2,XPNPEP3,RGS2,LYAR,FAM89B,POLR2I,TRAFD1,SUGP2,GBA,SYVN1,DAPK3,ARHGAP15,MASTL,UAP1,NFIL3,FN3KRP,YWHAZ,CTSA,TOB1,ADNP2,TCF12,PRKAB1,MDH2,SMARCA4,ORC1,RRN3,UBXN2A,IARS,CD3EAP,KIF14,EXOSC1,CS,CLTB,DNAL4,POU2AF1,UBQLN4,SELPLG,ATXN1,GLO1,OGDH,BICD2,CADM1,EDEM2,HERPUD2,TOLLIP,FANCE,MBD3,PDHX,RPS9,ARNTL,ANP32E,FKBP5,TMEM101,CCDC125,ABCA1,PDCD2L,GCLM,RAE1,DCTN2,NUP54,CHIC2,PAWR,MXD4,DCUN1D4,PIP4K2A,XPR1,FERMT3,KIF5B,KLHL20,SEC24C,RRBP1,ARHGEF2,ANP32A,LDLRAD3,STAT3,MYO5A,NIPAL3,AMPD2,TXNL1,PHF20L1,DCAF6,FAM49B,TMEM39A,ATP2C1,RFFL,COG1,RCOR1,PRMT2,TFEB,LEMD2,SERF1B,UPF1,ELMO1,ZC3H7B,DTX4,ZMIZ1,TERF1,HRAS,CCDC93,FGFR1OP,TMED7,PIGQ,AGPAT1,CNTROB,PPP1R16B,GSDMB,TTC9C,PDS5B,NUP153,SENP1,PGAP2,TMEM115,PLEKHM3,PLEKHF2,BRMS1,PWWP2B,TRIM47,WDR11,AXIN1,SMG9,LONP2,NDUFV2,CERK,SLC4A2,EZH1,ITGB5,LMNA,MCTS1,DDX56,EIF2S2,SLC38A5,FOXN2,CARS2,PRRC2A,C16orf72,RB1CC1,ZMYND11,PGS1,MYBL2,UHRF1BP1,SRSF5,MPG,MATR3,CYB5A,SETD3,TEX30,PTAR1,CNOT6,NDE1,EGLN1,ZNF207,ANKRD27,ABCA3,SARNP,IVNS1ABP,RMI2,MON1B,TMEM97,NIT2,NUF2,ZNF267,KTN1,APP,PRKD3,CLUAP1,ATP2A2,UTP18,GRSF1,DUT,ZCCHC2,ANAPC7,RNF19A,FAM76B,CLN6,GCC1,RNF169,ADCY7,ATP6V1G1,ENPP4,RNPS1,CDCA2,FKBP3,GPR137,DDX17,CHCHD3,PEX5,CDC16,HIPK2,MBOAT1,TICAM1,PDXK,ZBTB11,ANXA6,TMBIM4,GMCL1,UBE4A,IL21R,ETS1,ZNF92,CAPN2,ADD3,SUV39H2,TTLL12,TPCN1,TMX1,LYPLA2,HNRNPM,MFSD12,LDHB,PPP3CA,NUDT8,POLK,MTMR12,ZP3,PDE3B,KIF18A,CCDC6,WNT5B,MAPK6,LY75,SLC25A19,RGL1,PSAP,WDR76,IGBP1,FAF1,COX15,THOC1,AGRN,PPP1R15B,CSNK2A1,EBNA1BP2,GIT2,BIRC2,ATPAF1,DLG5,ABL2,XRCC2,ZFYVE27,MCMBP,PTPRK,CDC37,METTL1,SP3,HARS,GMFB,ESYT1,ANLN,RAB5B,RHEB,DPYSL3,TBC1D17,TIMM13,CDCA4,TONSL,NRM,NAGLU,ACTB,ZNF45,TMUB1,CTCF,ASAH1,DOCK11,CRLF3,ASXL2,LRRC14,NUS1,SLC27A4,AFF1,MDFIC,MAML1,CYTH1,NQO2,UTP15,EIF2AK1,EIF4G2,ZDHHC3,MOSPD3,ITPRIPL1,CDC27,SNAP23,TBPL1,PRMT7,KCTD7,NDUFA5,UGP2,DYNLL1,COPE,HCFC1R1,ZADH2,GGPS1,RPAIN,RAD23A,ATP6V0B,PDK2,STRBP,MRPL34,PDCD2,SAP30L,CLPTM1,RPL35,BTG2,DNAJC9,MTMR6,NFATC2,KDM1B,ARL5B,USP36,ATP1A1,CLK3,PSMD3,MAFK,CEP55,DNAJC17,ZNF436,NCOA1,SLC25A39,ZC3HC1,ZNF146,ATXN7L2,CDC40,GOLIM4,SMAP1,GNE,SMC6,ARFIP2,NKRF,CHAC2,BZW2,WRNIP1,SS18L1,CAMK2G,MLEC,ZNF202,PPWD1,FAM50B,RHOT2,TPD52L2,GOLGA7,TWSG1,GLG1,PGRMC1,FAM126A,RPS6KC1,UBE2C,PPCS,NDUFB6,TMEM41B,PLXNA1,CCNB1,SLC20A1,COMMD6,POLR3K,C14orf119,ASAP2,SNUPN,CNPY4,TFG,PLCL2,SEH1L,ATG9A,PBK,MKI67,DDX20,AMDHD2,GALNT7,SLC17A5,CCNF,FOXRED1,RBM47,WDR4,DHTKD1,TRAF5,HDAC2,PWWP2A,HSPH1,MAPRE1,CHTF18,KIF23,SLC35B1,NOTCH2,PMF1,JMY,FKBP1A,SNX18,ATIC,CTPS1,ATP6V0A2,PIKFYVE,RNF135,LPCAT1,EEF1D,TMED2,FTL,PHF10,DDX28,ZNF84,SIGMAR1,PIP4K2C,RIT1,PLEC,KDM3A,FAS,EPRS,ZNF777,TMEM54,QARS,PPP3R1,TCOF1,CABLES1,NRBP1,DNMT3A,RWDD1,CKLF,TRIP10,SF3B1,CAST,SUZ12,RPS6KA1,RAC1,GPR89A,OLA1,SNN,GNB2,FLAD1,APLP2,KDM2A,CDKN1B,TNPO2,TALDO1,ATP13A1,RFC3,MAPRE2,ERF,CUL3,SLBP,KIAA1586,H2AFV,GAR1,PSMB9,POLG2,DHX57,NSA2,HSPA4,JAK1,GOLGA8A,TBL3,SEL1L,H2AFX,KLHDC4,PDCD11,ATMIN,POLQ,OTUD5,NCOR2,ANKRD13D,PKP4,SCAMP3,BABAM1,CDCA3,SLC25A12,BLM,TMCC3,GTF2F1,CRAT,AHSA1,PRC1,UPF2,COPS7B,SLC38A10,CNOT6L,CNPY3,UBE2M,IFT46,TSHZ1,ZFP64,STRIP1,DENND4C,DENND1B,ILF3,LRRC1,RHOT1,TSR2,MARK2,PRDX1,PLD3,NUCB1,FBXO21,GNA12,C1orf131,PRDX3,PFDN4,HNRNPH3,TFDP1,STX18,KHSRP,ASNA1,VPS29,S100PBP,MIB2,IER2,NOP2,UBN1,DCAF15,NF1,ALKBH5,MOGS,TAF6L,BECN1,MAPK14,SNAPC4,RNF103,BCAT2,MBD4,METTL14,ZNHIT6,IMPAD1,RCSD1,PHTF1,KIF22,ZBTB22,OGG1,TRIM14,COPS8,FYTTD1,TRIM8,RRM2,SOX4,ABHD5,UBTF,CXXC4,PAF1,UEVLD,SPATA2,PQBP1,IARS2,ATXN2L,RPS15,PIGN,AGTRAP,CIB1,XPO7,SRRT,ZNF449,CAPZA1,GLTP,KIFAP3,BCL2,N4BP2,HP1BP3,THNSL1,CAND1,GNAS,TSC1,RBM25,CDCA5,ZFP90,RBBP4,ZBTB24,SMARCD1,MBD1,WASF2,MMACHC,TOMM20,GNPNAT1,MPHOSPH8,HNRNPUL2,CHD1,C2orf68,CCDC50,AKAP8,PARL,RPN2,CHTOP,F2R,FAM3A,TMEM14C,SCYL3,ABI1,HTRA2,MOSPD1,RLIM,FAM172A,ZNF500,NLN,WIPF1,BOLA1,BUD13,NDUFB1,PEF1,EIF3G,BTBD1,TAB2,CHCHD1,TULP3,WDR59,CANT1,SCARB1,GAS2,USP11,SMURF1,PPP2R2D,TSPAN5,CDS2,MAGEH1,EYA1,CDK2AP2,LETMD1,KLF13,RGS1,HDDC2,MAN1A1,FBXO5,GART,TANK,PELO,BRD7,MRPL11,SAMD4B,WDR81,MEN1,ZNF407,MFN2,COX8A,ZRANB2,SRSF3,MBD6,IDH3B,TATDN1,ATP6V1C1,TSC2,LACTB2,RBM4,ZNF275,ANKRD39,RPL23A,CDKN2C,NAPG,USF1,DNAAF2,MECR,AP1M1,UPRT,CRY2,ECD,MOB1A,RNF26,TIPARP,LRRC59,BAK1,ZNF559,RHOBTB3,GABPA,WBP1,NUTF2,ARF4,KRIT1,BOLA3,AHNAK,RAD18,RNASEL,CHPF2,PDCD4,NXT2,HIVEP3,KIAA0100,CLSPN,RHOC,DHX9,PDCD7,PSMD9,COPB2,TFAP4,CD59,RNFT1,MEGF8,RIMS3,EFTUD2,FBXO7,CPSF4,MRPL21,PHKG2,LUC7L2,SRSF11,EIF3L,MTA2,TYW1,USP10,ITM2A,SSR2,BCLAF1,MTX1,SFXN5,FNTA,TXNDC16,ZNF830,TMEM159,MRPL3,ALS2,TRIM41,KARS,POC1A,ANK3,PTTG1,TPX2,TBC1D13,DAZAP2,GLRX3,STMN1,C19orf48,REPS1,ABHD16A,FBXL6,SH3BP1,MTA1,UBA5,CLCN6,INTS12,RPRD1B,CGGBP1,CPNE1,FAM118B,GOPC,E2F3,CIRBP,CRNKL1,PFKFB3,GORAB,RAB1A,GIGYF1,PPP2CA,KIF2A,CCDC14,LSM6,RNF38,SNRPG,DMWD,USP13,ZFP91,TRMT6,IP6K2,SLC25A43,IFT27,PMVK,NEIL2,RRP36,SRXN1,RPA2,PSMD2,CLIC4,PDCD10,CBWD2,COQ4,ITGB8,ARF5,ARHGEF1,GTF2H2,FBXL19,TTPAL,UTP20,MAGT1,GPS2,DBI,SSNA1,MRFAP1L1,CD81,TMEM131,WDR13,FANCI,PAPOLA,CREM,FANCL,TET3,GLIS2,IL6ST,INTS1,ASB6,PLK1,RPP25,SEPT9,CELSR2,RBX1,APH1A,RAD51AP1,PSMG1,UBE2V1,EAF2,KRTCAP2,LUC7L,LSG1,NECAP2,TRIM4,AGPAT2,CHD3,E2F4,PRPF4,KPNA2,BEND6,CLN3,DNAJC30,FAM208A,NGLY1,POT1,RMND5A,HJURP,PHB2,DNAJB2,FAM53C,NKD2,KLC1,CDK13,ADCK5,COX4I1,DNAJB1,RAB6A,ARID1B,C1GALT1,MLX,UBE2Q2,CCP110,ZNF746,CTR9,NIPSNAP1,ABHD2,DCAF8,ACSL3,LDB1,MAP4K3,ARMC8,NMT2,IRF5,RPL36,HAUS8,MBIP,ORMDL2,COX7A2L,ZDHHC7,SIL1,FAM122A,UNC13C,BCCIP,SART1,TRAF7,TOR1AIP1,LAGE3,TM9SF3,ZNF121,OIP5,NRF1,WDR44,PPME1,PIN1,EFCAB11,RPAP1,CABLES2,LMAN1,AHCYL1,TOP1MT,STRAP,SPSB3,ZNF583,SNX25,ARHGAP17,ZNF780B,NUP155,DCLRE1C,MRPS14,RHBDF2,SUGP1,RBL1,FASTK,UBXN2B,STK38,AP1S1,SLC22A23,H3F3A,SMAD4,RAD51D,SLC30A9,CMAS,UNK,NADSYN1,HMGN3,NCAPG,SCYL2,FZD6,HERC3,GTPBP3,CTSS,ORC3,RNLS,YTHDC1,ACP2,HMGN5,CSRP1,METTL5,ABCF2,TUFM,RANGAP1,HAGH,API5,ZFR,SEC23IP,E2F1,USP20,RBPJ,PDCD6IP,MAX,LUZP1,GXYLT1,ADAM10,CXXC1,TSC22D3,AP3M2,CUL1,NANS,MYEF2,ANKRD26,PA2G4,NOL11,FIZ1,ZNF200,MARCH2,SLC26A2,SRP72,KLF10,LACTB,CBFB,RFC2,RAB2B,MAP3K4,HHEX,MAP4,MRPL27,BTF3,PTPDC1,NMD3,PTOV1,COX5B,DNAJC5,DHPS,ANKH,VAV2,PRKAA1,C16orf87,GSPT2,TATDN3,DLGAP4,PXMP2,PSEN1,ZNF79,PDXDC1,VPS25,NDUFS7,YY1AP1,FAM192A,RPN1,LHX8,ARPC5,TPST1,DAPK1,PIK3IP1,CYC1,SOCS5,PIGT,EMB,WDR1,ZNF574,C1orf35,EXOSC9,ARID1A,FXR1,GOSR1,MAP2K2,TWISTNB,AKAP1,XRCC5,HMGN2,PI4K2A,CAT,DERL1,MTHFD2,HSPBP1,ARAP1,USP32,FAM83D,CABIN1,SMPD4,GPI,CYTIP,TP53RK,REPS2,RAB11B,UROD,SLC39A13,BCL2L1,NUDT19,DECR1,RALB,SIAH1,ADCY9,LPIN2,SOCS6,TTC3,ANKLE2,OAF,VDAC2,EDF1,EML4,ERC1,ANKZF1,RAD51C,ZNF282,DSN1,HINT1,DGCR8,SAFB,HAGHL,RWDD4,FTSJ1,NCLN,BEND3,EYA2,DYNC1LI2,MANBA,SLC41A1,FAM76A,TKT,CBLL1,ARGLU1,POFUT1,FAM8A1,HEATR5B,HLA-A,EBP,RFWD3,FJX1,FUT8,BTF3L4,PTPN11,MRPL54,FEM1B,CNN2,MTX2,MSH6,PDLIM2,LONRF3,RFXANK,FBXO9,GUF1,RPL32,ZHX1,OAZ2,WDR91,HIGD2A,GPR89B,RORB,POLA2,ZNF76,MTX3,COPA,PHRF1,DST,RAB35,SIVA1,GPATCH1,TCEA1,DRAM2,TRAPPC13,SNRNP200,LAP3,NCK1,VHL,SREK1,ARHGDIB,PITPNB,HSPB11,BRWD1,PPM1G,SH3GLB2,BAZ1B,ACBD4,CAB39,STK11,CLU,CHEK2,TSTD2,MRPL13,CHPT1,DCAF5,CAPN1,UBE2D3,PPP1R12A,ZCCHC8,GORASP1,NACA,C19orf25,RPL15,PCSK7,EPN1,THRAP3,QSOX2,TTF1,NUP205,PRPF18,CHKA,DTL,MED10,ZRANB1,MCPH1,SLC12A2,ATP6V0D1,CSNK1G3,NUDT4,RPL6,VKORC1,SLTM,EVC2,KLHL15,SIAH2,SLC16A1,EHD4,SNRNP70,C11orf1,APOL2,N4BP2L2,SNX27,CHMP2A,CORO7,FEZ2,PMS2,UCK2,CLCC1,EXT2,MXD1,USP5,HNRNPA2B1,SAP130,NVL,PPP6C,CYB5R1,ZNF770,EBAG9,RNF25,PCGF6,METTL2A,PON2,HNRNPR,STAT6,HPS5,MAPK1,BRD9,TMEM33,DNAJC2,TRIP12,SHPRH,SCYL1,MYO9B,GFM2,SPPL2A,FASTKD3,FGFR3,PPIG,TMEM99,H2AFY,NDUFS8,ATG13,ERI3,FBL,FRMD8,SLC35A1,MICAL3,ELOVL5,TIMMDC1,HELB,PSPC1,MIER1,SCFD2,NDRG3,CDK11A,MTMR3,MEGF9,ACAT1,CENPT,PLOD3,RAB3IL1,RAB14,ADD1,KDM4A,MRPS15,XIAP,DHX8,GLUD1,PABPC4,CDK5,CALM2,PSMD1,NEK6,NSRP1,RABGAP1L,SRSF4,KCNAB2,PCBP2,MLST8,PLK3,ZNF672,MRPL43,HSDL1,TOPORS,MCL1,PPFIA3,SMC2,ICMT,SLC50A1,STOML2,LIMK1,ZNF689,PRDX5,ATE1,MLYCD,FBXL3,TFDP2,E2F2,PFKP,DDX42,SSRP1,MRPL9,MRPS2,STRN4,TOP2B,ZNRF3,DDRGK1,RAVER2,GNS,INTS7,INPP5A,MCM5,PHF14,NAGPA,TIMM8B,ETV3,DHX29,TEX10,MAN1B1,CBFA2T2,ABCF1,RHOB,LRRC14B,DTWD1,PTPRF,SCARB2,OSBPL11,CCDC86,DUSP3,MDH1,HEXA,RNF139,SNX14,ZNF296,TRERF1,UBR2,CHD1L,ACTR3,WDTC1,MYH9,CREBL2,NIPA2,PRKACA,SAFB2,ANKIB1,STAM,ARL6IP6,RAB21,SP100,ZKSCAN1,DDA1,NUP107,ANKRD13C,MAVS,CEP63,ATF2,RBM15,DCTN1,SHOC2,PSRC1,MAP4K4,ATP6V0A1,NUSAP1,NDUFA7,DNAJA1,TAZ,TAF2,C19orf54,RPLP1,WDR7,CBLN2,FUS,GEN1,LRP8,COIL,LRCH1,GALK1,ZNF786,RPS2,SESTD1,TRAK1,JMJD6,SIKE1,AKT1S1,KRI1,FBXO3,ERH,GATC,NDUFB4,PPP1R8,PRDM4,GTSE1,GEMIN6,DCP1A,SGCB,S100A6,IMPA2,NUDC,PDPK1,TK1,TNFAIP3,GALC,ZNF512,KIAA0930,MRPS10,DDX39A,RPA1,ZNF862,ZNF180,KEAP1,POLE,TATDN2,PITX1,CAPN7,LRPPRC,PML,HMGB2,USF2,ANAPC4,SRM,DDX47,MCCC1,S1PR2,SEC16A,SSR1,LIN9,PCNA,ZNF639,ETV6,PIK3R2,PPCDC,TXLNA,MYBL1,CCAR1,MRPL32,ABCC5,BAZ2A,PBXIP1,TLK1,MRPL12,EZR,LNX2,LRP5,BRCA1,PRKRA,STX16,EPB41,OPTN,SEPT1,SOCS4,QRSL1,OSGEPL1,GLCCI1,NUDT11,GEMIN7,LZTR1,RACGAP1,PPP3CB,B4GALT4,RLF,RAPGEF6,RB1,VMP1,PPIL2,MEA1,TIMELESS,AHDC1,ALDH18A1,TMEM8A,PREB,ABCC1,TRAPPC9,AACS,MEMO1,KRAS,RTF1,UBE4B,NFATC2IP,ARPC1A,ZNF174,PSMC4,GOLGA4,PALB2,PRPS2,NIPA1,TIGD2,RNF114,FOXM1,MRPL39,XAB2,SUMO2,DUSP22,COMMD8,RPL11,CSDE1,MDM2,CORO1A,MINPP1,POC5,DVL2,PSMA8,TIGD5,SLC26A6,CYP20A1,PRPF3,RPSA,SRSF1,DNAJC10,SCAP,ZNF700,PLEKHG4B,TIMM17A,FAU,LTA4H,AP2S1,USP53,INTS2,CTDP1,MIF4GD,CDT1,ARID5A,SUMF1,GGA2,CSNK1A1,RMI1,TFRC,PTPN2,IRF4,STARD9,NDUFV1,SLC1A4,CWC27,SLC35B4,DDX31,ABCD1,RPAP3,CNTN5,SNX2,ZMYM5,CCDC34,CHCHD6,BSDC1,CDKN2AIPNL,FBXO41,KPNA4,BIRC5,TFE3,SNAP29,CDCA7L,PKD2,CHMP7,SAT2,ZNF496,TAP1,NHLRC3,IKBIP,EIF1B,KIFC1,DBNDD1,CYB5RL,PARPBP,CDC25B,DNMT1,NOL12,ORAI2,USO1,AKT2,NOL8,GNG7,AURKB,MCFD2,SLC25A5,ZFAND5,MAK16,STT3A,EIF2D,ITGB1,PTPN7,UQCRH,RRS1,ARRB2,RTN3,ZNF598,DDX58,WSB2,PPIB,MUT,HLA-E,NDUFA4,MAN2B1,METTL3,CFLAR,RNF121,MEX3C,KLF16,HDAC7,DAD1,BDH1,PCYT2,GNAI2,ANKHD1,TERF2,MORC3,KCTD20,SEPT8,DCTD,PKM,TOMM40,PATL1,ADSS,SERTAD2,ZFP92,NSF,DCK,ACLY,VCPIP1,PPP6R3,PPP6R2,MAP3K5,YY1,CDK2,RNF14,ZC3HAV1,SYS1,ZBTB37,URB2,MAGED1,KLHL18,SLC25A44,AP1B1,SDHA,PAIP2,PHC2,CRKL,MOAP1,TERF2IP,CYHR1,ZNF75D,SHC1,UCHL5,NAA35,CDKN2AIP,CCT2,MKLN1,HMGN4,GALK2,CDC23,SHCBP1,AP4E1,PRDM11,VEZF1,PPP2R5A,ACYP1,STAT1,PPA2,TRIM32,RHEBL1,R3HCC1L,TCF3,MRI1,BRAP,AGPAT3,MYNN,SPR,RAB11A,REEP5,FOXO3,MAD2L2,CCDC28A,PIP5K1C,RBM17,MAT2B,PTEN,CENPJ,NCOA2,PACS2,SMC4,NEK7,NET1,PARP4,TBRG4,ANAPC2,YIF1A,SGSH,HGS,TTLL4,MFAP1,CCDC69,BRWD3,ESYT2,SKA3,NPHP4,UBE2E2,HNRNPAB,PLXNC1,ST13,DNAJC24,ZNF107,KIF2C,SLC29A1,AGFG1,SIRT2,USP48,UBQLN2,FKBP2,CUTC,EDC3,ZNF804A,RAP1A,THADA,EIF4A3,AP3S2,ATG3,DPYSL2,PPP1R12C,AKR1B1,JOSD1,NDUFB9,RP2,TECR,ARID4A,TIMM50,TDP1,DPM1,FOPNL,SLC16A7,SLC25A22,WDR82,STK17B,CHAF1A,GEMIN5,COPS6,PSMC1,SLC12A7,TM9SF4,ZNF768,MED13L,TIA1,MEF2A,EPHX2,RHBDD1,NFATC3,BUD31,ZNF335,KNTC1,UBE3C,ACAD8,ZNF189,ALDH9A1,KDELR1,TSTA3,CIC,OXR1,TMEM241,NAP1L1,NSMF,ODF2,EXOC4,NUP62,PITPNA,KIAA1328,NAA20,PTDSS1,MZT2B,PDSS2,C7orf26,TMEM106C,IMMT,ASH1L,CHERP,WDYHV1,PLAGL2,CHKB,TWF2,PAIP1,ANKRD28,FARSA,ANKLE1,SAR1A,SCAMP4,APOOL,PDIA6,ACSL5,AZI2,GFER,RAD54B,DAP3,ZNF317,AKNA,REEP4,CBX4,MIF,KIF3B,GOLPH3L,SH2D3A,CASP6,TOR3A,SRGN,DBF4,MFSD10,SAC3D1,CTNNBL1,YIF1B,CLDND1,TTC17,SLC25A1,GINS1,CSNK1G2,TELO2,HMGN1,ADAM17,NASP,ASPM,PPP1R21,PRKAR1B,SYMPK,TARS,MAPK3,HSPA1B,HLA-B,PLAA,ATAD2,ZNF330,OSBPL8,KBTBD7,PREPL |
| 7.425e-06 | -11.81 | GSE3982_BASOPHIL_VS_CENT_MEMORY_CD4_TCELL_UP | MSigDB lists | GSE3982_BASOPHIL_VS_CENT_MEMORY_CD4_TCELL_UP | 184 | 51 | 17377 | 2626 |
ANKRD27,NDUFV2,LUZP1,SF3B1,DAZAP2,MAPK14,MAP1LC3B,PSEN1,RUFY1,GIT2,MXD1,MAN1A1,PRNP,CTNNBL1,RALB,SLC44A1,PPP4R1,BRD7,CEP63,MARCH2,TALDO1,FAM3A,SAP30L,HTRA2,SMC4,TIMM8B,RHOA,CREG1,RB1CC1,GALC,CRNKL1,ESYT1,AZI2,ZDHHC3,DHX15,SH3GLB1,C22orf46,ABHD5,HLA-B,VEZF1,HHEX,PLAA,PPP2R5A,NSF,ACOX1,COX8A,ZDHHC7,YWHAZ,H3F3A,ZMIZ1,CHPT1 |
| 7.425e-06 | -11.81 | GSE41867_MEMORY_VS_EXHAUSTED_CD8_TCELL_DAY30_LCMV_DN | MSigDB lists | GSE41867_MEMORY_VS_EXHAUSTED_CD8_TCELL_DAY30_LCMV_DN | 184 | 51 | 17377 | 2626 |
CMAS,ZNF496,GNPNAT1,TMBIM4,ADD1,UBN1,PPP1R15B,CDK2AP2,MAGED1,ARFIP2,CDC42SE2,DCUN1D4,OAT,TMEM165,SYNRG,CPNE3,CAPN2,APLP2,IRF4,TNS3,RAP1A,ZKSCAN1,MEGF8,SLC44A1,HADHB,ANXA5,PDIA6,DRAM2,KDELR1,DCAF6,CREG1,PRRC2A,PBK,RDH10,NARF,JTB,USP22,MCFD2,KRTCAP2,MRPS14,GALNT2,UAP1,TMED10,ACOX1,PGRMC1,FAM122A,ATF6,SPCS3,CD81,SMAD4,S100PBP |
| 7.425e-06 | -11.81 | GSE17186_NAIVE_VS_CD21LOW_TRANSITIONAL_BCELL_CORD_BLOOD_UP | MSigDB lists | GSE17186_NAIVE_VS_CD21LOW_TRANSITIONAL_BCELL_CORD_BLOOD_UP | 184 | 51 | 17377 | 2626 |
MIF,TCF12,GMFG,ADD1,RPLP2,MUM1,CDK2AP2,ACAP1,SLC25A12,ZADH2,ATPAF1,MAT2B,PHC2,ADD3,SIAH1,DAD1,HDAC7,ZNF639,SSBP3,ZNF260,HADHB,PDCD2,CDC25B,RNF19A,METTL9,SGCB,FRMD8,SMC4,CYTH1,SEPT9,SNX2,NCK1,LDB1,ITM2A,LRRC8A,RFFL,PLEC,GALNT7,KRTCAP2,TANC1,ICAM2,EIF3H,MAGED2,GALNT2,PEX5,ARAP1,IMPDH1,GALNT10,CENPT,CBX4,PFKP |
| 7.425e-06 | -11.81 | GSE22886_IGG_IGA_MEMORY_BCELL_VS_BLOOD_PLASMA_CELL_DN | MSigDB lists | GSE22886_IGG_IGA_MEMORY_BCELL_VS_BLOOD_PLASMA_CELL_DN | 184 | 51 | 17377 | 2626 |
GLT8D1,LIME1,GOLPH3L,TMEM184B,TRIP12,TM9SF4,WDYHV1,MOGS,MXD4,NCAPG,STAM,ABHD14A,RPAIN,BIRC2,WRB,CDC73,SPAG5,USP5,FBXO5,GNS,CALM2,SLC1A4,IMPAD1,FUT8,RRBP1,SPTSSA,TFG,MTX2,BAK1,TIMP2,MLEC,LAP3,SELPLG,ATXN1,MRPL16,NDUFA7,CADM1,ARPC1A,API5,SLC50A1,PDHX,ISG15,MAGED2,SERF2,RBM47,MAGT1,NSF,CTBS,PTPN7,RBPJ,ATP6V1C1 |
| 7.425e-06 | -11.81 | GSE21380_TFH_VS_GERMINAL_CENTER_TFH_CD4_TCELL_DN | MSigDB lists | GSE21380_TFH_VS_GERMINAL_CENTER_TFH_CD4_TCELL_DN | 184 | 51 | 17377 | 2626 |
C19orf53,RPLP2,NDUFAF2,NF1,POC1A,SUZ12,UBXN1,SNX15,CUTA,PLAGL2,KLC1,CHCHD2,AKT1S1,FKBP2,NCAPG,GNB2,BCAP31,TFAP4,ZBTB45,NDUFB4,ARF5,ERI3,UBE2M,TMX1,ALDH9A1,PPIF,PLK1,TELO2,FTL,C16orf72,SIGMAR1,AKT2,DCAF8,LDB1,KCTD20,ATP6V0A1,SLC25A22,EIF2AK1,GSTCD,NEU1,C1orf122,PRDX5,VCPIP1,NCLN,TMEM101,NDUFS5,PTDSS1,RPS26,LRP8,UNC13C,SVIP |
| 7.425e-06 | -11.81 | GSE17721_CPG_VS_GARDIQUIMOD_12H_BMDC_DN | MSigDB lists | GSE17721_CPG_VS_GARDIQUIMOD_12H_BMDC_DN | 184 | 51 | 17377 | 2626 |
ASH1L,UBE2E2,LZTR1,H2AFZ,SLC41A1,UROD,NENF,CHKB,SLC35B1,DAZAP2,CCDC28A,TFRC,TMEM179B,RPA2,SNRNP25,RB1,ATP6V0B,C18orf32,INPP5A,TANK,AXIN2,EI24,CYB5R1,CABLES2,TALDO1,CARM1,TMX1,ABCC1,SHOC2,PSRC1,ERMP1,SEPT9,TSPAN31,WBP2,SSR2,THNSL1,NUTF2,PRKRA,SOX4,CYB5A,HSPA1B,DDOST,TMED10,GRIPAP1,ZNF330,TOMM6,BBX,GLG1,ANP32E,NANP,GLCCI1 |
| 7.425e-06 | -11.81 | GSE2585_CTEC_VS_THYMIC_MACROPHAGE_DN | MSigDB lists | GSE2585_CTEC_VS_THYMIC_MACROPHAGE_DN | 184 | 51 | 17377 | 2626 |
TMBIM4,LUZP1,TM9SF4,GSPT2,CENPF,FAM76A,CSNK2A1,CUL1,NOTCH2,ZNRF3,PAIP1,SRXN1,TNS3,MDM2,ZNF449,ARPC5,AP3S2,SEPT11,TTC3,KNTC1,CDC25B,CITED2,GNAI2,RBM15,SLC12A2,UBE2M,ATP6V0D1,STRAP,PCBP2,WDR41,USP34,SRSF11,NRAS,LONRF3,POLK,TACC1,COG1,PLEC,PITPNB,SMC2,RAB1A,PTTG1IP,NMT2,AKAP1,ALG3,RBM47,USF2,ZC3HAV1,ANXA11,DDB1,PFKP |
| 7.425e-06 | -11.81 | GSE25123_WT_VS_PPARG_KO_MACROPHAGE_DN | MSigDB lists | GSE25123_WT_VS_PPARG_KO_MACROPHAGE_DN | 184 | 51 | 17377 | 2626 |
BCCIP,C9orf78,KARS,RPS2,CKLF,RRP15,RPLP2,RBM8A,SMARCA4,AGPAT3,GTF3A,UBQLN2,CDIPT,PITHD1,CREM,FKBP1A,FASTKD3,UTP18,RAD23B,YBX1,MCMBP,PPA1,GPX4,SRSF10,TRAFD1,NASP,ERLIN1,RPL8,GTPBP4,LACTB,MRPL43,PSMG1,ARHGDIB,TXNL4A,COMMD4,DDX39A,CCT8,TARS,BTBD1,MAT2A,NSA2,RPL37,HINT1,SYNCRIP,PRDX3,TWSG1,RPS27A,CERS6,CTSA,VPS29,HIGD2A |
| 7.425e-06 | -11.81 | GSE16385_ROSIGLITAZONE_IL4_VS_IL4_ALONE_STIM_MACROPHAGE_12H_UP | MSigDB lists | GSE16385_ROSIGLITAZONE_IL4_VS_IL4_ALONE_STIM_MACROPHAGE_12H_UP | 184 | 51 | 17377 | 2626 |
SLC12A7,KIF3B,CYTIP,PARP12,UBN1,ABCC10,PRKAA1,TAP1,SMC6,CDK13,TGOLN2,RGS2,SLC20A1,SYNRG,HAUS2,SRRT,MBD4,RAD23A,KRR1,KDM2A,WDR44,IL6ST,DCP1A,TARDBP,EIF5,MVP,MCPH1,S100A6,VOPP1,ATP13A1,TRIM8,CDC123,TACC1,IDH3A,NOL8,MTMR6,KRAS,PRPF3,PBRM1,AMDHD2,TARS,RBM38,EIF3A,USP36,BTBD1,C19orf54,RBM47,STK38,HNRNPH3,CEBPG,TSPAN5 |
| 7.471e-06 | -11.80 | GO_METHYLATION | MSigDB lists | GO_METHYLATION | 233 | 61 | 17377 | 2626 |
ASH1L,DNMT3A,NOP2,CXXC1,SUZ12,MECP2,TRMT6,CTCF,RAB6A,EZH1,SNRPD3,WDR5,METTL3,MAT2B,TET3,IRF4,SUV39H2,METTL14,PRDM4,ZNF335,CTR9,AHCY,FAM86C1,FBL,DNMT1,NSUN4,FTSJ3,ARID4A,CARM1,METTL1,HEMK1,BAZ2A,MTA2,SNRPB,BTG2,METTL5,EHMT1,NSUN2,METTL2A,WDR82,RTF1,ICMT,METTL22,PRMT2,KDM1B,MEN1,KDM3A,MTR,TRIM28,MAT2A,PRDM11,DOT1L,GNAS,SETD3,CAMKMT,WDR4,FTSJ1,OGT,PRMT7,BEND3,GCSH |
| 7.484e-06 | -11.80 | IFIT2 (interferon induced protein with tetratricopeptide repeats 2) | protein interactions | 3433 | 45 | 20 | 17029 | 2761 |
HNRNPAB,RAB11B,DHX29,SNRPB,ILF3,SNRPD3,POLG2,MATR3,SNRPA,PABPC4,LMNA,ISG15,HNRNPA2B1,RPLP1,YBX1,SNRNP70,HNRNPDL,PABPC1,IFI16,TUBB |
| 7.537e-06 | -11.80 | mitotic G1 DNA damage checkpoint | biological process | GO:0031571 | 71 | 26 | 17256 | 2622 |
PLK3,PRKDC,BTG2,CCNB1,SOX4,CNOT11,CNOT3,CNOT9,RPA2,RFWD3,PCNA,MDM2,RPS27A,CENPJ,E2F4,TFDP1,E2F1,PML,CDKN1B,GTSE1,CNOT6,CHEK2,TFDP2,CNOT6L,CDK2,CARM1 |
| 7.537e-06 | -11.80 | mitotic G1/S transition checkpoint | biological process | GO:0044819 | 71 | 26 | 17256 | 2622 |
PLK3,BTG2,PRKDC,CCNB1,SOX4,CNOT11,CNOT3,CNOT9,RFWD3,RPA2,PCNA,MDM2,RPS27A,CENPJ,E2F4,TFDP1,E2F1,PML,GTSE1,CDKN1B,CNOT6,CHEK2,CNOT6L,TFDP2,CDK2,CARM1 |
| 7.559e-06 | -11.79 | GSE6092_B_BURGDOFERI_VS_B_BURGDORFERI_AND_IFNG_STIM_ENDOTHELIAL_CELL_UP | MSigDB lists | GSE6092_B_BURGDOFERI_VS_B_BURGDORFERI_AND_IFNG_STIM_ENDOTHELIAL_CELL_UP | 165 | 47 | 17377 | 2626 |
TRERF1,ADAM10,UROD,TMEM109,IKBIP,GGA2,RGS2,FOXO3,WRB,PIP4K2A,EXT2,HMG20A,TBC1D14,PIK3R2,EI24,KIFAP3,MAVS,CYB5R1,SLC35C2,CLN6,CNNM3,CTDSP2,KCNAB2,ALDH9A1,ANKLE2,GALC,NQO2,CCDC34,H2AFV,RFC2,NDRG3,TTC33,ASF1B,INF2,HHEX,TRIM47,SCARB2,TMEM41A,AHNAK,STAT6,FAM3C,MYO18A,APPL2,MDH1,NCOA1,GLCCI1,ZSWIM6 |
| 7.563e-06 | -11.79 | GO_POSITIVE_REGULATION_OF_BIOSYNTHETIC_PROCESS | MSigDB lists | GO_POSITIVE_REGULATION_OF_BIOSYNTHETIC_PROCESS | 1738 | 326 | 17377 | 2626 |
ZNF496,H2AFZ,CXXC1,HEXB,CCNL2,PARK7,CALM2,USF1,NOL11,DNM2,ECD,SENP1,AATF,GABPA,AKT2,TOPORS,AURKB,USP22,CBFB,RFC2,ARF4,STOML2,MAP3K4,HHEX,MID1IP1,SMAD2,RPS27A,AXIN1,PRDX5,OGT,RNASEL,TRIM52,TFDP2,SMAD1,ARRB2,TRAF5,HDAC2,SVIP,DDX58,HIVEP3,HSPH1,POLR2K,CHTF18,PRKAA1,EZH1,EIF2AK4,PSEN1,PSMD9,METTL3,CDC73,JMY,LMNA,CFLAR,DDRGK1,TFAP4,NSUN4,NUP85,PABPC1,EIF5A,FOXK1,MTA2,MYBL2,BCLAF1,ARID1A,ADRB2,CBFA2T2,ELK1,KDM3A,ABCF1,CCT8,CAT,SERTAD2,POLR2J,ETS2,GOLGA2,SETD3,RBMX,CEBPG,PPP3R1,PIAS2,CDK2,RNF14,CDKN2A,RHOG,TRERF1,RAF1,RPS6KA1,MAGED1,RAC1,CREBL2,APP,TERF2IP,CCNA2,SHC1,SP100,ADCY9,LPIN2,GMEB1,MAVS,RBM15,ATF2,RPRD1B,ADCY7,CCT2,PSRC1,BRD4,RFC3,POLR2L,WBP2,E2F3,CIRBP,POLR2D,EDF1,MEF2D,ERC1,TRIM28,SERP1,SUPT16H,DDX17,TAF2,SAFB,HIPK2,STAT1,ATF6,TICAM1,TRIM32,LRP8,ATMIN,RHEBL1,POU3F2,NCOR2,MECP2,TCF3,ABHD14B,WDR5,BLM,ETS1,FOXO3,MAD2L2,GTF2F1,WWP2,CCNK,PTEN,CREB1,CITED2,NCOA2,PPP3CA,KAT2A,NEK7,RFXANK,ILF3,ZP3,KLF6,PICALM,POLR2A,FADD,PRDX3,PITX1,TFDP1,HMGB2,DDX5,USF2,CD81,YWHAH,IGBP1,CCNC,ZBED3,RORB,HNRNPAB,THOC1,AGRN,GPBP1L1,NF1,FAM129A,SIRT2,MAPK14,CREM,TET3,PCNA,CDC42,EIF4A3,GLIS2,ZNF639,ETV6,PIK3R2,MYBL1,MTPN,ARID4A,TRIM14,SP3,DEAF1,TRIM8,NCK1,VHL,MRPL12,LRP5,UBE2V1,BRCA1,EAF2,SOX4,USP21,PAF1,UBTF,E2F4,BAZ1B,ZNF268,DVL1,CLU,CHEK2,PSMC1,POT1,ZNF564,PPP1R12A,PHB2,NACA,CIB1,CHCHD2,CTCF,MEF2A,PPP3CB,THRAP3,RLF,ASXL2,CRLF3,ARID1B,RB1,SUB1,NFATC3,MED10,SSBP3,ZNF746,BUD31,CTR9,YBX1,RBM3,MDFIC,MAML1,TRAPPC9,POLR2I,ERLIN1,ACSL3,LDB1,RTF1,KRAS,NFATC2IP,EIF2A,IRF5,PSMC4,RXRB,CAND1,GNAS,SYNCRIP,NLRC5,NUP62,ZFP90,RUVBL2,SMARCD1,TCF12,ASH1L,FOXM1,PLAGL2,SMARCA4,CHD1,PAIP1,RRN3,NRF1,PSMA6,NVL,PIN1,TARDBP,F2R,DVL2,MOSPD1,TIMP2,POLR2G,RNF25,NFATC2,RPS9,SCAP,TAB2,RBL1,MAFK,STAT6,ARNTL,NCOA1,SCARB1,AKNA,MAPK1,ABCA1,SMAD4,BCL2L12,SLC30A9,NAT14,CTDP1,DNAJC2,EYA1,KLF13,PAWR,HMGN3,PTPN2,IRF4,ARHGEF2,BRD7,SS18L1,STAT3,TGFB1,HMGN1,DCAF6,HMGN5,PRKDC,PRMT2,MEN1,MAPK3,HSPA1B,TFEB,TRIM26,ATAD2,TFE3,E2F1,PKD2,TAF12,RBPJ,ZMIZ1,NR2F2,HRAS,IFI16 |
| 7.594e-06 | -11.79 | REACTOME_ACTIVATION_OF_THE_PRE_REPLICATIVE_COMPLEX | MSigDB lists | REACTOME_ACTIVATION_OF_THE_PRE_REPLICATIVE_COMPLEX | 30 | 15 | 17377 | 2626 |
POLA2,RPA2,MCM10,POLE,PRIM2,MCM5,CDT1,DBF4,CDC6,ORC1,MCM2,ORC3,CDK2,RPA1,PRIM1 |
| 7.625e-06 | -11.78 | Golgi Cisternae Pericentriolar Stack Reorganization | REACTOME pathways | R-HSA-162658 | 14 | 10 | 10287 | 1696 |
PLK1,USO1,GOLGA2,GORASP1,GORASP2,CCNB1,RAB1A,CCNB2,MAPK1,MAPK3 |
| 7.637e-06 | -11.78 | signal transduction involved in mitotic cell cycle checkpoint | biological process | GO:0072413 | 63 | 24 | 17256 | 2622 |
PLK3,PRKDC,BTG2,CCNB1,SOX4,CNOT11,CNOT3,CNOT9,PCNA,MDM2,RPS27A,CENPJ,E2F4,TFDP1,E2F1,PML,GTSE1,CDKN1B,CNOT6,CHEK2,TFDP2,CNOT6L,CDK2,CARM1 |
| 7.637e-06 | -11.78 | intracellular signal transduction involved in G1 DNA damage checkpoint | biological process | GO:1902400 | 63 | 24 | 17256 | 2622 |
PLK3,PRKDC,BTG2,CCNB1,SOX4,CNOT11,CNOT3,CNOT9,PCNA,MDM2,RPS27A,CENPJ,E2F4,TFDP1,E2F1,PML,GTSE1,CDKN1B,CNOT6,CHEK2,TFDP2,CNOT6L,CDK2,CARM1 |
| 7.637e-06 | -11.78 | signal transduction involved in mitotic G1 DNA damage checkpoint | biological process | GO:0072431 | 63 | 24 | 17256 | 2622 |
PLK3,PRKDC,BTG2,CCNB1,SOX4,CNOT11,CNOT3,CNOT9,PCNA,MDM2,RPS27A,CENPJ,E2F4,TFDP1,E2F1,PML,GTSE1,CDKN1B,CNOT6,CHEK2,TFDP2,CNOT6L,CDK2,CARM1 |
| 7.637e-06 | -11.78 | signal transduction involved in mitotic DNA damage checkpoint | biological process | GO:1902402 | 63 | 24 | 17256 | 2622 |
PLK3,PRKDC,BTG2,CCNB1,SOX4,CNOT11,CNOT3,CNOT9,PCNA,MDM2,RPS27A,CENPJ,E2F4,TFDP1,E2F1,PML,GTSE1,CDKN1B,CNOT6,CHEK2,TFDP2,CNOT6L,CDK2,CARM1 |
| 7.637e-06 | -11.78 | signal transduction involved in mitotic DNA integrity checkpoint | biological process | GO:1902403 | 63 | 24 | 17256 | 2622 |
PLK3,PRKDC,BTG2,CCNB1,SOX4,CNOT11,CNOT3,CNOT9,PCNA,MDM2,RPS27A,CENPJ,E2F4,TFDP1,E2F1,PML,GTSE1,CDKN1B,CNOT6,CHEK2,TFDP2,CNOT6L,CDK2,CARM1 |
| 7.644e-06 | -11.78 | vesicle coating | biological process | GO:0006901 | 67 | 25 | 17256 | 2622 |
USO1,TRAPPC9,GORASP1,CUL3,MCFD2,RAB1A,PEF1,SEC16A,ANKRD28,CD59,SEC31A,SEC23IP,PDCD6,GOLGA2,NSF,TMED10,SEC24C,PPP6C,PPP6R3,TFG,LMAN1,PPP6R1,TMED2,CSNK1D,PREB |
| 7.646e-06 | -11.78 | GSE24671_CTRL_VS_BAKIMULC_INFECTED_MOUSE_SPLENOCYTES_UP | MSigDB lists | GSE24671_CTRL_VS_BAKIMULC_INFECTED_MOUSE_SPLENOCYTES_UP | 189 | 52 | 17377 | 2626 |
PWWP2A,UBL3,CDS2,SF3B1,CAST,SRSF6,CDT1,C5orf30,BRAP,MYH9,MXD4,HCFC1R1,DOCK11,SYNRG,FAM8A1,UBXN2A,WDR44,IL6ST,RCSD1,ZNF326,PIKFYVE,RPL22L1,FGFR1OP2,ADCY7,TGFB1,CDKN2AIP,PPP3CA,CYTH1,FAM49B,ZMYND11,MAP4K3,MTMR12,WBP1,AZI2,CBFA2T2,HERPUD2,STX16,BSDC1,GIGYF1,ARHGAP15,TFEB,PLD3,TSC1,RAD18,CSK,TAB2,MYO18A,NRM,CAB39,DVL1,ZMIZ1,HIGD2A |
| 7.646e-06 | -11.78 | GSE21380_NON_TFH_VS_GERMINAL_CENTER_TFH_CD4_TCELL_DN | MSigDB lists | GSE21380_NON_TFH_VS_GERMINAL_CENTER_TFH_CD4_TCELL_DN | 189 | 52 | 17377 | 2626 |
PRPF38B,FAM208B,PPP1R12A,CLSPN,IVNS1ABP,MANBA,GMCL1,NHLRC3,B4GALT4,SPPL2A,TERF2IP,SEC11A,SMC3,IARS,KIF13B,ATP13A3,BCL2,RP2,CREB1,ATF2,ARID4A,CSNK1G3,USP34,SRSF11,BIRC3,TAOK1,CUL3,DNAJC9,MEF2D,CAPZA2,HERPUD2,GOSR1,MAT2A,DDX23,RAD51C,EIF4ENIF1,MID1IP1,SEC23IP,RBM47,TXNDC16,PARG,CAPN7,MAP4,U2SURP,PPA2,VCPIP1,C4orf46,ATF6,SAMD8,SRSF3,GEN1,DDX42 |
| 7.646e-06 | -11.78 | GSE17721_CPG_VS_GARDIQUIMOD_6H_BMDC_DN | MSigDB lists | GSE17721_CPG_VS_GARDIQUIMOD_6H_BMDC_DN | 189 | 52 | 17377 | 2626 |
TP53RK,CASP6,SCYL1,UCK2,IRF3,GYG1,NANS,METTL3,XPR1,SEC11A,SNX18,ZNF639,GRSF1,NUP107,EI24,PARL,AHDC1,BCAP29,MVP,TMBIM1,USP34,VOPP1,PBXIP1,ERLIN1,NSUN2,RDH10,PSMG1,PRPF3,SMC2,GAR1,TAZ,LUC7L,MBD3,NEU1,MAT2A,CLNS1A,MYO1F,ADSS,UTP20,PON2,WAS,ETS2,TTC13,CSNK1G1,TPP2,STK38,CEP55,PPM1G,LMBR1,USP11,NUMB,S100PBP |
| 7.646e-06 | -11.78 | GSE360_L_DONOVANI_VS_M_TUBERCULOSIS_DC_UP | MSigDB lists | GSE360_L_DONOVANI_VS_M_TUBERCULOSIS_DC_UP | 189 | 52 | 17377 | 2626 |
H2AFZ,ABCC10,NACA,DCTN2,GADD45G,TRIO,XIAP,DLGAP4,ASAH1,COX4I1,AP1B1,IFT27,FOXO3,PABPC4,CNOT3,TFAP4,IRF4,MDM2,TBC1D22A,GOT2,SIVA1,BDH1,TTC3,AHCY,CPSF4,LPCAT1,IMPA2,CDC5L,TK1,ATG9A,TUFM,FRAT2,KCNQ1,ESYT1,PRKRA,ZFAND5,EIF4H,H2AFV,TARS,IRF5,STOML2,MYO1F,MAGED2,TFE3,ATXN2L,LY75,HMGB2,RUVBL2,SCARB1,LTA4H,USF2,TRAF5 |
| 7.646e-06 | -11.78 | GSE43955_1H_VS_42H_ACT_CD4_TCELL_WITH_TGFB_IL6_UP | MSigDB lists | GSE43955_1H_VS_42H_ACT_CD4_TCELL_WITH_TGFB_IL6_UP | 189 | 52 | 17377 | 2626 |
SEPHS2,RMND5A,IER2,RWDD1,PHB2,EIF3D,UROD,TRAK1,FLOT1,GYG1,EIF1B,C19orf48,FERMT3,RRN3,MDM2,IARS,GRSF1,ZNF260,EI24,SLC26A2,ZNRD1,RPL22L1,CTDSP2,TMX1,PCBP2,KCNAB2,RLIM,SPTAN1,SEC61B,RAB7A,EMB,SELPLG,MRPL16,ADRB2,RAB5B,NDRG3,ABHD5,RPL36,FBXO21,FNTA,QARS,COX7A2L,EXOC4,CRCP,MRFAP1L1,CTSA,BTF3,BRWD3,CHMP7,CBX4,ZNF146,PDCD4 |
| 7.646e-06 | -11.78 | GSE22886_NAIVE_CD4_TCELL_VS_DC_DN | MSigDB lists | GSE22886_NAIVE_CD4_TCELL_VS_DC_DN | 189 | 52 | 17377 | 2626 |
WSB2,TBC1D12,UQCR10,DYNLL1,LAMTOR3,CSNK2A1,CYCS,MAN2B1,ZNF267,ATP6V1B2,PSEN1,REEP5,POLR3K,ZNF804A,RAB21,ATP6V0B,MLX,CLIC4,DAPK1,H2AFY,ANXA5,TALDO1,TIMM8B,FTL,MKLN1,CREG1,PPT1,LAP3,RAB7A,KIAA0930,MTMR6,SMC2,VDAC1,RHEB,PRDX1,MFN2,PI4K2A,KEAP1,ATP6V1D,MTHFD2,SERF2,DUSP3,PRDX3,MFAP1,SNAP29,TIMM17A,COX8A,ZMIZ1,PGAM1,AP2S1,ATP6V0E1,TMEM33 |
| 7.653e-06 | -11.78 | ERLIN2 (ER lipid raft associated 2) | protein interactions | 11160 | 99 | 34 | 17029 | 2761 |
COX15,CYLD,TMUB1,EWSR1,TCF3,HNRNPUL2,FLOT1,PSEN1,PSMD2,ATP2A2,RNF5,HNRNPM,TIMM50,DCTN1,CCT2,SEC61B,APH1A,RAB7A,ERLIN1,ADRB2,SYVN1,VDAC1,RHOT1,ARSK,TRIM28,DERL1,PDCD6,HSPA4,DUSP3,SCAP,CLN3,PPP6R3,RNF139,TUBB |
| 7.653e-06 | -11.78 | SERBP1 (SERPINE1 mRNA binding protein 1) | protein interactions | 26135 | 99 | 34 | 17029 | 2761 |
CYLD,VAV2,CUL1,CSNK2A1,WDR5,SDHA,PARK7,APP,WWP2,PA2G4,HUWE1,AHSA1,TARDBP,UPF2,PABPC1,FYTTD1,CUL3,RPS10,RPS24,TOPORS,EIF2A,MCM2,ISG15,CAND1,CHD3,HNRNPR,RPS14,MAP4,ATP5F1A,FUS,FAU,CD81,ARRB2,RPS26 |
| 7.727e-06 | -11.77 | GSE15624_CTRL_VS_6H_HALOFUGINONE_TREATED_CD4_TCELL_DN | MSigDB lists | GSE15624_CTRL_VS_6H_HALOFUGINONE_TREATED_CD4_TCELL_DN | 151 | 44 | 17377 | 2626 |
RRP15,CHD1L,ADO,NANS,SND1,SNRPD3,GLRX3,TUBGCP2,USP5,CALM2,PA2G4,PRDM4,EFTUD2,RPN2,MRPL21,CPSF4,ZNRD1,TMEM14C,EEF1D,ALDH9A1,FDFT1,CDC37,EIF5A,PGAP2,RPP25,TCTEX1D2,HARS,NEK7,SLC26A6,SLBP,SEPT7,MBD3,CCDC127,KEAP1,HSPBP1,RAD18,CCDC6,PPM1G,PDXK,SPRYD4,TAF6,LRP8,CHID1,IPO4 |
| 7.727e-06 | -11.77 | GO_PROTEIN_LOCALIZATION_TO_NUCLEUS | MSigDB lists | GO_PROTEIN_LOCALIZATION_TO_NUCLEUS | 151 | 44 | 17377 | 2626 |
POLA2,NUP188,TSC2,PHB2,RAE1,TOR1AIP1,NUP54,SUPT7L,RPAIN,NUP205,LMNA,RPL11,MDM2,SNUPN,NUP107,TNPO2,TNPO3,PIKFYVE,F2R,STAT3,NUP85,MORC3,TGFB1,PPP3CA,SEC61B,TOR1AIP2,TOPORS,NUP155,NUTF2,PTTG1IP,MAPK3,PAF1,HHEX,KPNA4,KPNA1,OSBPL8,ARNTL,PML,NUP62,KPNA2,DVL1,MAPK1,TOB1,IPO4 |
| 7.749e-06 | -11.77 | vesicle budding from membrane | biological process | GO:0006900 | 92 | 31 | 17256 | 2622 |
USO1,TRAPPC9,GOLPH3L,GORASP1,CUL3,MCFD2,RAB1A,PEF1,SEC16A,ANKRD28,SEC31A,CD59,SEC23IP,PDCD6,CHMP4A,GOLGA2,NSF,TMED10,SAR1A,SEC24C,MYO18A,PPP6C,DNM2,VPS4A,LMAN1,PPP6R3,TFG,PPP6R1,TMED2,CSNK1D,PREB |
| 7.803e-06 | -11.76 | RNA polymerase complex | cellular component | GO:0030880 | 149 | 43 | 18223 | 2701 |
INTS2,POLA2,CTDP1,POLR2K,ZNF768,TAF6L,POLR3K,CDC73,GTF2F1,MED8,MED10,INTS7,INTS1,CTR9,INTS12,TAF5L,POLR1B,TCEA1,ZNRD1,GTF2H2,RPRD1B,ERCC1,POLR2I,RPRD1A,KAT2A,POLR2L,POLR2G,PRIM2,HELB,POLR2D,POLR3GL,RTF1,EDF1,TWISTNB,POLR2A,PRIM1,PAF1,TAF2,POLR2J,TBPL1,CRCP,TAF12,TAF6 |
| 7.825e-06 | -11.76 | MAPK3 (mitogen-activated protein kinase 3) | protein interactions | 5595 | 256 | 69 | 17029 | 2761 |
TSC2,RPS6KA1,RAF1,MAGED1,FKBP2,STMN1,MAPK14,LYN,RBM4,CREM,TTC9C,RAB4A,NUP153,ATF2,ILKAP,HTRA2,CSTF1,USO1,GMFB,BRCA1,CDC23,MCM2,VDAC1,USP21,GEMIN5,PPP2CA,UBTF,MKNK1,SMAD2,ATP1A1,TULP3,PTPN7,CHEK2,PTPDC1,ARRB2,MAPK1,NMD3,ZC3HC1,DHPS,TCF3,LAMTOR3,TOP2B,ATP5F1B,ETS1,GRK2,DAPK1,PTPN11,LTN1,DCP1A,BCL2,MAP3K14,STAT3,MTMR12,ELK1,SYMPK,MAP2K2,MAPK3,PRDX3,CCDC6,L3MBTL3,GPS2,DUSP3,PML,BTBD10,TAF6,NUP58,APOL2,IFI16,RNF114 |
| 7.844e-06 | -11.76 | GSE22886_TH1_VS_TH2_48H_ACT_DN | MSigDB lists | GSE22886_TH1_VS_TH2_48H_ACT_DN | 194 | 53 | 17377 | 2626 |
WASF2,MAX,PARP12,PLXNC1,UGP2,HEXB,AGPAT1,ZFYVE21,ZNF267,XPNPEP3,CRLF3,DNAJB9,SSR1,PRNP,HERC3,ARPC5,LPIN2,PHTF1,FBXW2,RPN2,AFF1,TAF5L,CLDND1,PLCL2,FAM171A1,TMED2,CAMK2G,NAGPA,DENND4C,MAN1B1,PARP4,SSR2,KRAS,RTF1,PTTG1IP,PSMB9,EML4,NMT2,ANKRD10,TMEM127,SGSH,SMAD2,RBM47,SNAP23,CAB39,PKD2,TRIM52,ZNF45,SMAD1,HEXA,RTN3,ATP6V0E1,ZBTB24 |
| 7.844e-06 | -11.76 | GSE360_DC_VS_MAC_B_MALAYI_LOW_DOSE_UP | MSigDB lists | GSE360_DC_VS_MAC_B_MALAYI_LOW_DOSE_UP | 194 | 53 | 17377 | 2626 |
WSB2,MBD1,KARS,H2AFZ,ANXA6,TMEM109,CIB1,METTL3,NDUFS4,CRKL,CDKN2C,DECR1,GART,CDC42,HUWE1,KIF14,ETV6,RAD23B,ANP32A,TECR,MOB1A,PIKFYVE,SPTSSA,STAT3,HTRA2,ALDH9A1,LDHB,MLEC,IDH3A,POLR2D,MFNG,NDUFA7,PKMYT1,ESYT1,OGFR,GOSR1,EIF4G2,RHEB,HMGN2,RDH11,BRMS1,ATP6V1D,PCM1,CERS6,STAT6,STK38,PTPN7,WDR7,SRSF3,COPS6,PLOD3,COIL,TUBB |
| 7.844e-06 | -11.76 | GSE360_L_DONOVANI_VS_T_GONDII_MAC_DN | MSigDB lists | GSE360_L_DONOVANI_VS_T_GONDII_MAC_DN | 194 | 53 | 17377 | 2626 |
IER2,CHERP,TCF3,UCK2,LAGE3,MED13L,PABPC4,SAC3D1,CREM,TFAP4,INPP5A,SIVA1,NAP1L4,FAM3A,AMPD2,CPNE1,TELO2,POLR2I,AATF,MAPKAPK3,CPOX,MRPL12,ILF3,TUFM,EZR,DNAJC9,PSMG1,KCNQ1,TMEM147,MCM2,MEN1,HAGH,ODC1,H2AFV,SNRPA,FADD,ALG3,HGS,PEX5,BIRC5,SCAP,RBL1,SAFB,KPNA2,PIEZO1,SCARB1,TRAF5,SMURF1,HRAS,PURA,PFKP,BYSL,ZBTB24 |
| 7.844e-06 | -11.76 | GSE5463_CTRL_VS_DEXAMETHASONE_TREATED_THYMOCYTE_UP | MSigDB lists | GSE5463_CTRL_VS_DEXAMETHASONE_TREATED_THYMOCYTE_UP | 194 | 53 | 17377 | 2626 |
MBD1,CMAS,PHB2,VAV2,COPE,TAP1,TRAK1,TOP2B,SLC4A2,SLC35B1,AP1B1,PDCD7,SLC20A1,CMTM6,WDR48,CDKN2C,FKBP1A,MLX,CLIC4,SIAH1,HDAC7,CS,GTSE1,TNPO2,BRI3,ABCD1,TAGLN2,SLC35C2,ASB6,HDHD2,RNF5,TGFB1,CYTH1,KLF10,SEPT9,CIC,SELPLG,CAMSAP1,UBE4B,SOX4,EIF3G,RDH11,BOLA3,GALNT2,AHNAK,STAT1,MPV17,YWHAH,SMAD4,LONP2,CBX4,NUDT3,BYSL |
| 7.852e-06 | -11.75 | GCM_ZNF198 | MSigDB lists | GCM_ZNF198 | 110 | 35 | 17377 | 2626 |
RMND5A,GNE,FOXO3,FAM8A1,REPS1,HMG20A,PAIP1,HEATR5B,FBXO3,FANCL,SMC3,MEX3C,BRPF3,RABGAP1L,SS18L1,TARDBP,CHTOP,CDC5L,KAT7,NUDT4,ACSL3,CRNKL1,ARID1A,PRKRA,ZFAND5,BSDC1,CAND1,VEZF1,SCARB2,EIF4ENIF1,SMAD2,RBM25,ZHX1,HNRNPH3,LUC7L3 |
| 7.859e-06 | -11.75 | PPIB (peptidylprolyl isomerase B) | protein interactions | 5479 | 95 | 33 | 17029 | 2761 |
CYLD,EWSR1,TMBIM4,SUZ12,DHX9,RRM1,IRF3,FKBP2,SDHA,WDR48,FKBP1A,RPN1,MDM2,PCNA,DNM2,PCBP2,UBQLN4,VHL,MKI67,RANGAP1,MCM2,VKORC1,USP21,SUGP1,PCM1,TXNDC16,MAGT1,HINT1,RBMS1,WDR76,PPP5C,CDK2,PFKP |
| 7.899e-06 | -11.75 | GSE41867_NAIVE_VS_DAY15_LCMV_CONE13_EFFECTOR_CD8_TCELL_DN | MSigDB lists | GSE41867_NAIVE_VS_DAY15_LCMV_CONE13_EFFECTOR_CD8_TCELL_DN | 170 | 48 | 17377 | 2626 |
POC1A,MAGED1,UBXN1,AP3M2,KLF13,CDC42SE2,C19orf48,LCLAT1,CHD1,HMG20A,PABPC4,COPB2,CRKL,VAV1,UCHL5,PIN1,TARDBP,NAP1L4,CDC5L,PPAN,NIPAL3,CLCN3,LARS,MAPRE2,TRIM8,PRIM2,C16orf72,CAMSAP1,NARF,CRNKL1,ZBED5,SREK1,HTATIP2,CDC23,MCFD2,AP4E1,MAK16,XRCC5,IWS1,IDE,ZNF777,OSBPL8,CNOT6,WDR76,RNASEL,MAPK1,BYSL,TMEM33 |
| 7.899e-06 | -11.75 | GSE40493_BCL6_KO_VS_WT_TREG_UP | MSigDB lists | GSE40493_BCL6_KO_VS_WT_TREG_UP | 170 | 48 | 17377 | 2626 |
HSPH1,CTDP1,PRKAB1,GOLIM4,ATXN3,RWDD1,ADAM10,URB2,UROD,TRIO,TATDN3,UBE2Q1,CUL1,COPB2,SEC11A,AHCTF1,UCHL5,LPIN2,PTPN11,DDX31,AQR,TFG,LMAN1,N4BP2,RLIM,SAMD4B,COPS8,RPAP3,DDX24,PPT1,NCK1,NSUN2,UTP15,RCOR1,EZR,PNPLA8,GUF1,APPL1,NMT2,EIF3A,GOLGA4,TWSG1,ERGIC3,SEL1L,GLG1,ARAP1,DYNC1LI2,DDB1 |
| 7.899e-06 | -11.75 | GSE13485_CTRL_VS_DAY1_YF17D_VACCINE_PBMC_UP | MSigDB lists | GSE13485_CTRL_VS_DAY1_YF17D_VACCINE_PBMC_UP | 170 | 48 | 17377 | 2626 |
SEPHS2,TP53RK,ZCCHC9,TOR1AIP1,LAMTOR3,SLC25A12,SLC25A44,IKBIP,CCDC28A,FBXO5,CRKL,NUDT19,MRPL50,RAB21,GRSF1,GMEB1,ZNF200,RP2,MINPP1,RBM15,MOSPD1,STAU1,PHF20L1,ABHD2,RFFL,RCOR1,RTF1,DCUN1D5,SLC17A5,TTC33,RAB22A,CLNS1A,ARF4,ZFR,PPP2CA,KPNA1,MFAP1,KBTBD7,COX5A,DHTKD1,DUSP11,PRPF4,BTBD10,MRPL13,SMNDC1,RNF114,TMEM33,CCDC137 |
| 7.913e-06 | -11.75 | BENPORATH_SOX2_TARGETS | MSigDB lists | BENPORATH_SOX2_TARGETS | 677 | 144 | 17377 | 2626 |
CCDC93,PNISR,GXYLT1,UQCR10,TMEM109,ENSA,KIF2C,SNRPD3,C14orf119,PRNP,ZNF428,DPYSL2,SRSF4,SLC44A1,DNM2,USO1,APH1A,MRPL43,KIF15,DIDO1,ICMT,PRPSAP1,LSG1,ARF4,DPYSL3,IWS1,HHEX,TBC1D17,NIP7,OGT,ST3GAL2,RRS1,CLN3,TSTD2,RPS26,HDAC2,UBE2D3,PPP1R2,PHF23,GGA1,GSPT2,GADD45G,TIA1,RPL15,ARID1B,MCTS1,VASP,MEX3C,KLHL5,SSBP3,ZNF335,KNTC1,FTL,TIMM8B,NUDT4,SUGP2,RDH10,BCLAF1,EXOSC9,CAPZA2,KDM3A,EIF4G2,NCDN,RDH11,MOSPD3,MAGED2,DCAF11,MYO9A,RNF14,CABLES1,USP7,XAB2,ORC1,RCOR3,PCBP1,GGPS1,APP,RAD23A,OIP5,HNRNPA2B1,FARSA,RBM23,RRN3,DDA1,MRPS27,FAM76B,TALDO1,CDK12,ZNF770,CFL1,DVL2,PRPF19,SAP30,ATP6V1G1,UBQLN4,MAPRE2,E2F3,FRAT2,ABHD11,NUSAP1,RAD54B,DDX17,C19orf54,NDUFA11,RPLP1,H2AFX,H3F3A,TUBB,DNAJC2,MYNN,AKT1S1,HMG20A,RMI1,PIP5K1C,GTPBP3,PTPN2,MAT2B,CLIC4,ADD3,NDUFA2,HUWE1,BTF3L4,ANP32A,FBXL19,STAT3,TMEM160,ABCF2,ILF3,WDR81,KIF11,DDX39A,SNRPA,PRDX1,CBX3,ATAD2,ACOX1,PARG,OAZ2,PPP1R11,ASNA1,DDX5,TAF12,UBE2C,IFI16 |
| 7.917e-06 | -11.75 | GO_POSITIVE_REGULATION_OF_VIRAL_PROCESS | MSigDB lists | GO_POSITIVE_REGULATION_OF_VIRAL_PROCESS | 84 | 29 | 17377 | 2626 |
PPIB,CTDP1,CHMP2A,STAU1,POLR2I,POLR2G,POLR2L,POLR2K,RAB7A,TRIM11,PPIE,YTHDC2,POLR2D,SMARCA4,CHMP2B,CHD1,POLR2A,GTF2F1,RAD23A,TFAP4,POLR2J,ZNF639,CHMP4B,MDFIC,VPS4A,PABPC1,CFL1,DDB1,SRPK2 |
| 7.953e-06 | -11.74 | DAZARD_RESPONSE_TO_UV_SCC_DN | MSigDB lists | DAZARD_RESPONSE_TO_UV_SCC_DN | 119 | 37 | 17377 | 2626 |
YTHDF3,CTCF,SLC25A44,FOXO3,CHD1,PHC2,CRKL,KIFC1,ASAP2,TNFAIP8,KDM2A,SIAH1,ATP13A3,NUP153,TIPARP,MORC3,CSTF1,RYBP,SHOC2,TNFAIP3,ERF,AMD1,TLK1,E2F3,SEPT8,MCL1,SOX4,FADD,ANKRD46,KIF2A,TRAM2,MFAP1,SIAH2,RBPJ,RRS1,COIL,ZNF146 |
| 7.953e-06 | -11.74 | STEARMAN_LUNG_CANCER_EARLY_VS_LATE_UP | MSigDB lists | STEARMAN_LUNG_CANCER_EARLY_VS_LATE_UP | 119 | 37 | 17377 | 2626 |
OTUD5,CAST,SF3B1,ANK3,TIA1,KLF13,CTCF,CCNL2,WDR48,PAIP2,KIF5B,APLP2,ZNF639,TPST1,TNPO2,SLC35A1,CGGBP1,YTHDC1,NRAS,DPM1,CADM1,WDR81,H2AFV,SRSF1,SCARB2,DNAJC10,OSBPL11,VPS26B,PGRMC1,GLG1,PIAS2,MPV17,PKD2,VPS4A,SLC22A23,MAPK1,SMAD4 |
| 7.953e-06 | -11.74 | KEGG_LYSOSOME | MSigDB lists | KEGG_LYSOSOME | 119 | 37 | 17377 | 2626 |
GGA1,MANBA,HEXB,AP3M2,ASAH1,SUMF1,MAN2B1,AP1B1,GGA2,AP3S1,GNS,ATP6V0B,CTSS,AP3S2,AP1M1,ATP6V0A2,CLTB,ATP6V0D1,GM2A,NAGPA,ACP2,PPT1,GALC,GBA,ATP6V0A1,SLC17A5,AP4E1,NEU1,SCARB2,SGSH,NAGLU,AP1S1,CTSA,ATP6V0C,PSAP,CLN3,HEXA |
| 8.003e-06 | -11.74 | G2/M transition of mitotic cell cycle | biological process | GO:0000086 | 132 | 40 | 17256 | 2622 |
FGFR1OP,MAPRE1,PPP1R12A,FOXM1,DYNLL1,DCTN2,ENSA,CUL1,HAUS4,CCNB1,PRKACA,HAUS2,RAB8A,CCNA2,CCP110,CENPJ,PPME1,DNM2,FBXL7,CEP63,CDC25B,DCTN1,PLK3,PLK1,PKMYT1,BORA,OPTN,MASTL,HAUS8,TAF2,PCM1,RPS27A,ODF2,SSNA1,CHEK2,NDE1,CCNB2,CDK2,TUBB,CSNK1D |
| 8.016e-06 | -11.73 | CLN3 (CLN3, battenin) | protein interactions | 1201 | 91 | 32 | 17029 | 2761 |
COX15,IMMT,CDS2,SCAMP3,SLC35B2,TFRC,NUP205,FANCI,RPN1,ATP2A2,ARF5,RPN2,CYC1,GEMIN4,TECR,SLC25A1,TELO2,SIGMAR1,DPM1,PRKDC,VDAC2,DDX20,SLC25A22,SLC25A5,ARF4,CAND1,ATP1A1,DDOST,SEC61A1,ECPAS,TMEM33,ESYT2 |
| 8.030e-06 | -11.73 | intracellular pH reduction | biological process | GO:0051452 | 44 | 19 | 17256 | 2622 |
CLCN3,PPT1,RAB7A,GPR89A,ATP6V0A1,ATP6V1B2,ATP6V0B,ATP6V1D,CLIC4,ATP6V0A2,ATP6V0C,ATP6V1C1,CLN3,CLN6,ATP6V0E1,ATP6V0D1,GPR89B,ATP6V1G1,SNAPIN |
| 8.048e-06 | -11.73 | antigen processing and presentation of exogenous peptide antigen | biological process | GO:0002478 | 174 | 49 | 17256 | 2622 |
KIF3B,HLA-E,DYNLL1,DCTN2,TAP1,KLC1,KIF23,RACGAP1,ARF1,KIF2C,AP1B1,ITGB5,PSMD9,HLA-A,PSMD2,CTSS,PSMA6,PSMD1,SEC24C,CAPZA1,DNM2,AP1M1,AP2B1,KIFAP3,KIF22,TAP2,DCTN1,PSMA8,RAB7A,PSMB7,KIF15,PSMA1,CAPZA2,PSMB9,KIF11,PSMB3,PSMC4,KIF2A,SEC31A,CTSL,HLA-B,KIF18A,PSMD8,PSMD3,SNAP23,AP1S1,AP2S1,PSMC1,DYNC1LI2 |
| 8.049e-06 | -11.73 | MRPS28 (mitochondrial ribosomal protein S28) | protein interactions | 28957 | 56 | 23 | 17029 | 2761 |
MRPL42,NDUFB6,MRPS2,MRPS15,MDH2,MRPL12,MRPS26,NDUFA7,CAND1,DAP3,SYNCRIP,HNRNPR,GRSF1,ZNF746,PQBP1,MRPS27,TRMT10B,NDUFB9,RBM3,CFAP20,MRPL13,MRPL32,HNRNPM |
| 8.049e-06 | -11.73 | Ube2i (ubiquitin-conjugating enzyme E2I) | protein interactions | 22196 | 56 | 23 | 17029 | 2761 |
NDC1,NUP188,RAE1,TCF3,SUMO2,SLC2A1,DHX9,NUSAP1,RANGAP1,NUP155,NUP205,FAS,SP100,HIPK2,GMEB1,NUP107,NUP153,GLE1,SMPD4,NUP85,SENP1,AAAS,SEH1L |
| 8.049e-06 | -11.73 | Ybx1 (Y box protein 1) | protein interactions | 22608 | 56 | 23 | 17029 | 2761 |
DDX28,HNRNPAB,NOP2,HNRNPUL2,MRPL12,MRPL43,DHX9,MRPS26,ILF3,HNRNPF,MRPL16,MATR3,PABPC4,ZFR,SYNCRIP,HNRNPR,RBMX,ZNF326,TRA2B,DDX5,FBL,HNRNPDL,PABPC1 |
| 8.091e-06 | -11.72 | IGSF8 (immunoglobulin superfamily member 8) | protein interactions | 93185 | 191 | 55 | 17029 | 2761 |
RPS15,RPS2,RPLP2,TMX4,CSNK2A1,SNRPD3,RPL11,RPL23A,HNRNPA2B1,RPL17,MCM5,HADHB,YBX1,RPL19,PDIA6,PABPC1,PCBP2,CFL1,EEF1D,TMX1,HNRNPM,TMEM160,EIF3L,FTL,RPL35,SNRPB,MBLAC2,RPL6,RPL8,ILF3,TBRG4,PKM,RPL27A,RPS9,EIF3G,DHX15,EIF3H,EIF3A,XRCC5,RPL36,SUPT16H,DDX17,EIF3K,SYNCRIP,RPS14,DDX5,TCOF1,SRSF3,FAU,RBBP4,CD81,PURA,PDCD4,TUBB,IFI16 |
| 8.094e-06 | -11.72 | GNF2_CKS1B | MSigDB lists | GNF2_CKS1B | 37 | 17 | 17377 | 2626 |
RFC3,ASPM,CDCA8,TPX2,KIF2C,AURKB,SMC2,KIF11,ASF1B,PA2G4,CCNA2,IARS,BIRC5,ATIC,RNASEH2A,UBE2C,ESPL1 |
| 8.106e-06 | -11.72 | VAPB (VAMP associated protein B and C) | protein interactions | 9217 | 155 | 47 | 17029 | 2761 |
CTU2,COX5B,COX4I1,UBE4A,PRKACA,SYNRG,HEATR5B,JMY,NDUFS4,AHCTF1,NOL11,WDR44,YBX1,RPN2,SLC26A2,MICAL3,SLC39A9,SNX25,OSBP2,CELSR2,SEPT9,SNX2,TACC1,RB1CC1,FAM118B,PPT1,VHL,PRKAR1B,TMEM216,ARHGEF12,MTMR12,NFATC2,MAP4K3,NDUFA7,VKORC1,LSG1,CAND1,OSBPL11,DDOST,ACBD4,USP20,ASNA1,PITRM1,CCNB2,EYA2,FAF1,FAM83G |
| 8.112e-06 | -11.72 | TSSC4 (tumor suppressing subtransferable candidate 4) | protein interactions | 10078 | 87 | 31 | 17029 | 2761 |
SNRNP200,CDC40,GPBP1L1,C1orf112,XAB2,MTA2,SNRPB,PPIE,CRNKL1,DHX8,GMCL1,SNRPD3,TXNL4A,APP,NCDN,DDX23,TERF2IP,KPNA1,IDE,GOLGA2,MFAP1,EFTUD2,BUD31,GPATCH1,SNRPG,ECD,RUVBL2,AQR,PRPF19,SPTAN1,CDC5L |
| 8.124e-06 | -11.72 | WD40_repeat | interpro domains | IPR001680 | 266 | 67 | 18492 | 2768 |
CORO7,COPA,TRAF7,WDR13,POC1A,WDTC1,GNB2,WDR44,UTP18,FBXW2,TAF5L,CORO1A,UTP4,STRAP,SEH1L,CSTF1,WDR41,PRPF19,MLST8,MIOS,LRBA,SMU1,WDHD1,WDR82,EML4,GEMIN5,BRWD1,WDR11,SCAP,TBL3,CORO1C,WDR59,WDR4,WDR7,PRPF4,DMWD,PPP2R2D,DCAF5,AAAS,WSB2,CDC40,RAE1,STRN4,WDR5,COPB2,WDR48,RFWD3,DTL,PREB,DCAF6,DCAF8,WDR1,WDR18,UTP15,WDR81,PPWD1,ARPC1A,SEC31A,PLAA,DCAF11,WIPI2,WDR76,WDR62,WDR91,RBBP4,WDR45B,BRWD3 |
| 8.138e-06 | -11.72 | TCERG1 (transcription elongation regulator 1) | protein interactions | 10915 | 83 | 30 | 17029 | 2761 |
SRSF11,WASF2,CYFIP1,BRD4,PSPC1,SF3B1,CYFIP2,PCGF1,UBE2I,LUC7L,PCBP1,SF3A2,POLR2A,DNAJB9,HSPA1B,CHAF1A,SRSF1,RPA1,SF3B2,RPA2,WAS,CBWD2,CHD3,CBWD1,PSAP,ABI1,DDB1,HNRNPM,DDX42,SRSF10 |
| 8.138e-06 | -11.72 | NDUFA9 (NADH:ubiquinone oxidoreductase subunit A9) | protein interactions | 4704 | 83 | 30 | 17029 | 2761 |
NDUFA5,COX15,NDUFV2,COA3,IMMT,NDUFS1,TIMMDC1,UQCR10,VDAC2,NDUFA4,KRAS,NDUFA7,VDAC1,NDUFB1,NDUFS7,NDUFS4,SSR1,SDHB,HLA-B,NDUFV1,NDUFA2,NDUFB4,NDUFA11,GTSE1,YBX1,NDUFB9,NDUFS8,NDUFS5,ATP6V1C1,EYA2 |
| 8.184e-06 | -11.71 | GSE7568_CTRL_VS_3H_TGFB_TREATED_MACROPHAGES_WITH_IL4_AND_DEXAMETHASONE_DN | MSigDB lists | GSE7568_CTRL_VS_3H_TGFB_TREATED_MACROPHAGES_WITH_IL4_AND_DEXAMETHASONE_DN | 156 | 45 | 17377 | 2626 |
PIGM,YTHDC2,HEXB,RAB23,TIA1,ATG2B,PLXNA1,DCUN1D4,PARN,RNF103,ANKRD28,LIN9,ATP13A3,ANKRD13C,CRY2,CLDND1,TAGLN2,STAT3,CNNM3,MGAT5,DRAM2,ANKLE2,STAU1,GCC2,PHF20L1,RPRD1A,RB1CC1,ZMYM5,RNF25,CAMSAP1,USP22,MACF1,MTR,ZFR,FBXO28,CHD3,CERS6,CSK,CORO1C,PTAR1,FAM122A,ACBD4,WDR76,HIPK3,ANAPC4 |
| 8.184e-06 | -11.71 | GSE6269_HEALTHY_VS_STAPH_AUREUS_INF_PBMC_UP | MSigDB lists | GSE6269_HEALTHY_VS_STAPH_AUREUS_INF_PBMC_UP | 156 | 45 | 17377 | 2626 |
RECQL,PNISR,PARP12,MRPL42,DCAF15,CXXC1,TIA1,SLC25A12,SMC6,SMARCA4,CDK13,ETS1,FANCL,ADD3,MTMR4,MTA1,LPIN2,ATP6V0A2,UPF2,CDK12,TRIM14,USO1,RFC3,MAPRE2,ZNF500,SLC16A7,NFATC2IP,LY6E,SPPL2B,USP21,PDHX,RHOB,ISG15,PRIM1,HLA-B,SYNCRIP,RBM25,BRD2,C1orf109,BBX,STAT1,PML,GLG1,TRIM32,IFI16 |
| 8.190e-06 | -11.71 | HIST1H1E (histone cluster 1 H1 family member e) | protein interactions | 3008 | 116 | 38 | 17029 | 2761 |
RPS15,RPS2,CYLD,ZCCHC9,NOP2,SF3B1,CTCF,EBNA1BP2,BRIX1,CDK11B,SF3B2,KRR1,KRI1,CMSS1,MED8,MCM5,RBM34,CTR9,DDX31,GLE1,FTSJ3,FYTTD1,STAU1,TEX10,ILF3,RPS10,MCM2,GAR1,MAK16,DHX57,SRSF1,CBX3,UBTF,DERL1,UPF1,RBMS1,CD81,PURA |
| 8.190e-06 | -11.71 | NOP58 (NOP58 ribonucleoprotein) | protein interactions | 51602 | 116 | 38 | 17029 | 2761 |
SART1,COX15,NIFK,DDX47,NOP2,SUZ12,SUMO2,CSNK2A1,EBNA1BP2,UBE2I,LMNA,RPL11,KRR1,DDX56,EIF2S2,ZNF746,RPL19,TARDBP,FBL,FTSJ3,DDX24,GTPBP4,UTP15,RPL6,RPS24,PRPF3,VDAC1,CDK11A,DHX15,CAND1,UTP20,KPNA1,TBL3,RPS14,RUVBL2,TCOF1,RRS1,NMD3 |
| 8.193e-06 | -11.71 | GO_DNA_TEMPLATED_TRANSCRIPTION_TERMINATION | MSigDB lists | GO_DNA_TEMPLATED_TRANSCRIPTION_TERMINATION | 97 | 32 | 17377 | 2626 |
CDC40,SARNP,THOC1,POLR2K,SRSF6,RBM8A,SNRPD3,TTF1,POLR3K,PAPOLA,ZNF473,EIF4A3,CD3EAP,SRSF4,POLR1B,CHTOP,GTF2H2,ZNRD1,CSTF1,SRSF11,POLR2L,SNRPB,RNPS1,SLBP,SRSF5,DDX39A,POLR2A,TWISTNB,SRSF1,UBTF,SRSF3,SNRPG |
| 8.215e-06 | -11.71 | GSE17974_CTRL_VS_ACT_IL4_AND_ANTI_IL12_72H_CD4_TCELL_DN | MSigDB lists | GSE17974_CTRL_VS_ACT_IL4_AND_ANTI_IL12_72H_CD4_TCELL_DN | 175 | 49 | 17377 | 2626 |
INTS2,PIGM,IMMT,DHPS,PDAP1,CENPF,NENF,SLC29A1,SND1,TWF2,SLC25A43,TMEM165,BCAP31,BCAT2,ASPHD2,HNRNPA2B1,DLG5,HOMER1,RAP1A,CLIC4,C4orf3,GOT2,BDH1,HADHB,GEMIN6,TCEA1,GLE1,SGCB,C12orf75,TK1,HPDL,PSMG1,MPG,PRDX1,PRIM1,ANKZF1,RAD51C,KEAP1,AGPAT2,NRM,DBI,IARS2,FAM83D,ACAT1,RUVBL2,CDK2,ZNF146,RAD51D,RHEBL1 |
| 8.264e-06 | -11.70 | REACTOME_NUCLEOTIDE_EXCISION_REPAIR | MSigDB lists | REACTOME_NUCLEOTIDE_EXCISION_REPAIR | 48 | 20 | 17377 | 2626 |
ERCC1,RFC3,POLR2I,POLR2G,POLR2L,POLR2K,XAB2,POLR2D,RFC2,POLR2A,RPA1,RPA2,PCNA,POLR2J,POLE,RAD23B,XPA,TCEA1,GTF2H2,DDB1 |
| 8.264e-06 | -11.70 | GO_POSITIVE_REGULATION_OF_MITOTIC_NUCLEAR_DIVISION | MSigDB lists | GO_POSITIVE_REGULATION_OF_MITOTIC_NUCLEAR_DIVISION | 48 | 20 | 17377 | 2626 |
TGFB1,PLK1,GORASP1,PHB2,CUL3,LRP5,NUSAP1,RAB1A,BECN1,FBXO5,RB1,GOLGA2,BIRC5,PTEN,NSMCE2,CDCA5,H2AFY,UBE2C,ESPL1,TERF1 |
| 8.264e-06 | -11.70 | GNF2_DENR | MSigDB lists | GNF2_DENR | 48 | 20 | 17377 | 2626 |
SRP72,DDX47,MRPL9,RWDD1,SUMO2,MRPS10,EIF3A,PAPOLA,HSPB11,SYNCRIP,HNRNPR,RBMX,QARS,HNRNPH3,TRA2B,TARDBP,RBM15,CCDC59,ZNF146,SMNDC1 |
| 8.278e-06 | -11.70 | KRAS (KRAS proto-oncogene, GTPase) | protein interactions | 3845 | 448 | 108 | 17029 | 2761 |
KARS,NDC1,DDX47,FEZ2,TOMM20,THOC1,KMT2E,ADAM10,NF1,UQCR10,RAF1,KIF2C,BRIX1,UBE2I,DUSP22,KCMF1,APP,OIP5,CCNA2,SHC1,KDM2A,IARS,EIF4A3,PIN1,PIK3R2,NUP107,RPF2,CARM1,PLK1,COPS8,KDM3B,ENPP4,CCT2,SHOC2,PGGT1B,NOL8,CRNKL1,PRPF3,DIDO1,ICMT,TXNL4A,EIF3G,EIF3A,UBTF,PON2,CDC16,JAK1,TMED10,STT3A,TPP2,IARS2,UHRF2,RRS1,LTA4H,MAPK1,NXT2,UNK,PARP12,GOLIM4,SH2D3A,CDCA8,RLF,PSEN1,CDC73,PIP4K2A,ARID1B,NUP205,RPA2,ERH,SUV39H2,VMP1,HUWE1,RNFT1,PPP1R8,ZNF260,ANXA5,COPS7B,BCL2,UBE3B,FBL,MVP,MCPH1,TNRC18,MTX2,UBE2M,JMJD4,TTPAL,RHOA,SNX2,CREG1,C16orf72,NQO2,ITM2A,KRAS,HMGN2,CNOT9,EPRS,NEK1,C1orf131,FNTA,CDC27,SNAP23,QARS,PML,FAM83D,ANAPC4,HIGD2A,EGLN1 |
| 8.316e-06 | -11.70 | organophosphate metabolic process | biological process | GO:0019637 | 968 | 196 | 17256 | 2622 |
RAB14,COX15,PIGM,PPCS,NDUFB6,UQCR10,PIGQ,HEXB,AGPAT1,CSNK2A1,CDIPT,ATP5PF,RUFY1,PARK7,MBD4,IMPAD1,PIK3R2,SLC44A1,RAB4A,PPCDC,HADHB,UPRT,NDUFB9,SLC26A2,OGG1,KCNAB2,PGAP2,DPM1,RRM2,PRPSAP1,MPC1,STOML2,ABHD5,AGPAT2,COX5A,DHTKD1,UQCRH,CLN3,CHPT1,NUDT11,PFKP,NDUFV2,COX5B,PIGN,RRM1,RAB23,NDUFA4,COX4I1,CYCS,NDUFS7,CHKA,NDUFS4,PDXP,NUS1,TIGAR,PYURF,INPP5A,ATIC,CTPS1,MSH2,TPST1,PIGG,ATP6V0A2,PCYT2,CYC1,PIKFYVE,LPCAT1,FDFT1,PIGT,NUDT4,PGS1,PIP4K2C,DCTD,PKM,PI4K2A,ADSS,MBIP,DCK,PRPS2,COX7A2L,ACLY,TBPL1,LPCAT4,MDH1,SAMD8,DNPH1,SMPD4,GPI,ATP5F1A,NIPSNAP2,PTDSS1,NUDT3,NDUFA5,KARS,UGP2,SUCLG1,MDH2,UCK2,STARD7,OLA1,ZFYVE21,UCK1,CHKB,ADPGK,EFL1,SLC35B2,ATP6V1B2,GGPS1,LCLAT1,CPNE3,SDHA,FLAD1,VAV1,MTMR4,DUT,LPIN2,ADCY9,MINPP1,TALDO1,GPD1L,GPX4,ADCY7,CPNE1,CGAS,PFKFB3,MTMR6,ATP6V0A1,OGDH,NDUFA7,NDUFB1,TAZ,PDHX,HINT1,NT5C3B,GUCY1B1,NDUFA11,MBOAT1,PDXK,MAPK1,GALK1,NADSYN1,CDS2,NDUFS1,MECP2,TKT,AGPAT3,ABHD14B,ARF1,IP6K2,ATP5F1B,PMVK,PIP4K2A,HDDC2,PLPP5,NEIL2,PIP5K1C,ERH,FGFR3,NDUFV1,GART,NDUFA2,NDUFB4,PTEN,PTPN11,NDUFS8,NDUFA3,RNLS,IMPA2,LDHB,AMPD2,TGFB1,RHOA,TK1,GUK1,LDHA,NADK2,ADSL,MTMR12,PNPLA8,ATP5MF,PDE3B,HSPA1B,MTMR3,PLAA,ATP5MC3,PARG,OSBPL8,DBI,COX8A,NAXE,IMPDH1,ACAT1,FAM126A,NDUFS5,PARP10,PGAM1 |
| 8.322e-06 | -11.70 | regulation of mRNA stability | biological process | GO:0043488 | 160 | 46 | 17256 | 2622 |
DHX9,YTHDF3,THRAP3,PSMD9,MAPK14,PARN,METTL3,PAIP1,PABPC4,FASTKD3,PSMD2,PSMA6,PSMD1,EXOSC7,METTL14,EXOSC1,AXIN2,DCP1A,ANP32A,YBX1,TARDBP,CNOT6L,PABPC1,SAMD4B,EXOSC6,PSMA8,PSMB7,CIRBP,PSMA1,TBRG4,EXOSC9,FXR1,PSMB9,PSMB3,PSMC4,UPF1,SYNCRIP,HNRNPR,RPS27A,PSMD8,PSMD3,E2F1,KHSRP,YWHAZ,RNASEL,PSMC1 |
| 8.345e-06 | -11.69 | ELMSAN1 (ELM2 and Myb/SANT domain containing 1) | protein interactions | 91748 | 35 | 17 | 17029 | 2761 |
TRERF1,DPM1,MYH9,SEC16A,MAPK14,RPA1,ZMYM3,GNAS,TFAP4,RPA2,CCNA2,USP11,CLTB,PDLIM5,CDK2,ZC3H3,HDAC2 |
| 8.369e-06 | -11.69 | transcription by RNA polymerase II | biological process | GO:0006366 | 837 | 173 | 17256 | 2622 |
RORB,CCNC,ZNF76,IER2,MAX,THOC1,PHRF1,RBM8A,TAF6L,SNRPD3,CCNB1,SNAPC4,PAPOLA,USF1,EIF4A3,GLIS2,ZNF639,INTS1,ETV6,SRSF4,TAF5L,TCEA1,ECD,MYBL1,ARID4A,CARM1,ELOF1,CDC5L,DEAF1,KLF10,GABPA,SNRPB,ELOA,PBRM1,EAF2,BRCA1,SOX4,CBFB,IWS1,PAF1,SMAD2,E2F4,BTF3,DVL1,ZNF45,TFDP2,SMAD1,ARRB2,E2F2,FUBP1,SSRP1,HIVEP3,POLR2K,ZNF768,DHX9,MEF2A,CDK13,PMF1,THRAP3,NOTCH2,CDC73,SRRT,TFAP4,SUB1,NFATC3,MED8,MED10,INTS7,SSBP3,CTR9,YBX1,ICE2,MAML1,CPSF4,SRSF11,POLR2I,ELL2,LDB1,MYBL2,RTF1,SRSF5,ELK1,IRF5,RXRB,POLR2J,RBMX,MED15,NFIL3,TBPL1,CEBPG,NRBP1,TCF12,MBD1,ASH1L,SARNP,PTTG1,SMARCA4,PLAGL2,IRF3,NRF1,ZNF473,GMEB1,NABP1,RPAP1,INTS12,TARDBP,CHTOP,ATF2,CDK12,RPRD1B,DVL2,CSTF1,POU2AF1,POLR2L,POLR2G,INTS13,E2F3,RNPS1,POLR2D,WBP2,SLBP,ELP4,NFATC2,MEF2D,TRIM28,SRSF1,SUPT16H,TAF2,VEZF1,HIPK2,STAT6,ARNTL,ATF6,SNRPG,NCOA1,AKNA,SMAD4,INTS2,POU3F2,CTDP1,CDC40,SRSF6,KLF13,NKRF,ETS1,FOXO3,WWP2,GTF2F1,CCNK,IRF4,PRDM4,NABP2,CARF,CITED2,CREB1,GTF2H2,STAT3,RPRD1A,KAT2A,ZNF202,DDX39A,KLF6,SYMPK,POLR2A,TFE3,PITX1,TFDP1,DDX5,RBPJ,TAF12,SRSF3,TAF6,USF2 |
| 8.385e-06 | -11.69 | YWHAE (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon) | protein interactions | 7531 | 433 | 105 | 17029 | 2761 |
COX15,CYLD,TSC2,SF3B1,RAF1,KIAA0232,CUL1,TWF2,MAPK14,PCBP1,SDHA,PAPOLA,HNRNPA2B1,SPINDOC,ATP6V0B,TNFAIP8,SRSF4,CDKN1B,TRA2B,CRY2,MAST2,CDC25B,C8orf59,TP53BP2,EIF5,CDC37,CDC5L,BRD4,BIRC3,ARHGAP45,TLK1,ELOA,CUL3,POLR2D,ATXN1,NFATC2,BRCA1,DNAJA1,MCFD2,MCM2,VDAC1,TAZ,PRPSAP1,CLNS1A,CHAF1A,SRSF1,STOML2,ANKZF1,AFDN,H2AFX,TRIM32,TFDP2,ARRB2,PSMC1,POT1,CBX4,ZC3HC1,TUBB,PARD3,UNK,NCOR2,MCM10,PPP1R2,SRSF6,FAM53C,UBXN1,PRKAA1,NKD2,KLC1,KIF23,ATP5F1B,CDK11B,CSNK1A1,FOXO3,CDC73,WWP2,MCTS1,DTL,KIF5B,CAPN2,VASP,HUWE1,CENPJ,HDAC7,ATIC,ARHGEF2,RBM3,TGFB1,SAMD4B,TNFAIP3,KIAA0930,RPL6,RAB3IP,MACF1,MARK2,CBX3,TFEB,TSC1,PCM1,YWHAZ,RUVBL2,ATP5F1A,MAP3K5,CDK2,YWHAH |
| 8.410e-06 | -11.69 | TIEN_INTESTINE_PROBIOTICS_24HR_DN | MSigDB lists | TIEN_INTESTINE_PROBIOTICS_24HR_DN | 214 | 57 | 17377 | 2626 |
PPIB,HSPH1,TMED7,GCLM,RPS2,NQO1,CDK2AP2,SDF2L1,CSNK1A1,DNAJB9,PRNP,RPL23A,VASP,SLC1A4,HUWE1,MTA1,TANK,LPIN2,ARHGEF2,TTC3,TCEA1,TTC17,CREB1,TFG,PDIA6,ATF2,PABPC1,TMED2,KDELR1,CDC5L,EIF5A,FTL,IFRD1,CLCN3,TMEM39A,TSPAN31,NUDT4,RPS24,CDC6,RPL27A,MAP2K2,SERP1,ARF4,SH3GLB1,PTPRF,DNAJC10,ALDH3B1,ZNF282,MTHFD2,TFE3,RPS14,NFIL3,SEL1L,CEBPG,CBX4,PDCD4,ADNP2 |
| 8.444e-06 | -11.68 | Oxidative phosphorylation | WikiPathways | WP623 | 54 | 22 | 5312 | 837 |
NDUFA5,NDUFV2,NDUFS1,NDUFB6,NDUFA4,ATP5F1B,NDUFA7,ATP5MF,NDUFB1,ATP5PF,NDUFS7,NDUFS4,NDUFV1,NDUFA2,ATP5MC3,NDUFB4,NDUFA11,NDUFS8,NDUFB9,NDUFS5,ATP5F1A,NDUFA3 |
| 8.504e-06 | -11.67 | GSE25085_FETAL_LIVER_VS_FETAL_BM_SP4_THYMIC_IMPLANT_UP | MSigDB lists | GSE25085_FETAL_LIVER_VS_FETAL_BM_SP4_THYMIC_IMPLANT_UP | 180 | 50 | 17377 | 2626 |
EXOC3,DNAJC2,MMACHC,PTMS,H2AFZ,CDCA8,RACGAP1,ABHD14B,NANS,TWF2,STAM,GFM2,BCAT2,SF3B2,DDX56,CCNA2,RPL17,PRC1,KIF22,KNTC1,CORO1A,MED22,PDLIM2,CCT2,EIF3L,PSRC1,RPL35,NSDHL,PPP1R21,RFXANK,CKAP2L,NUSAP1,PRPF3,USP22,RIT1,ICAM2,FXR1,ARHGAP15,DHX57,EIF3K,SDHB,NSA2,RPL32,ACAT1,PPP1R11,BTF3,HEXA,CCNB2,UBE2C,TUBB |
| 8.504e-06 | -11.67 | GO_FC_RECEPTOR_SIGNALING_PATHWAY | MSigDB lists | GO_FC_RECEPTOR_SIGNALING_PATHWAY | 180 | 50 | 17377 | 2626 |
WASF2,ACTR3,VAV2,RAC1,CUL1,PPP3CB,NCKAP1,PSMD9,LYN,CALM2,VAV1,PSMD2,NFATC3,PSMD1,PSMA6,SHC1,CDC42,ARPC5,PIK3R2,ABI1,PDPK1,CYFIP1,PPP3CA,NRAS,PSMA8,NCK1,PSMB7,PSMA1,WIPF1,KRAS,NFATC2,UBE2V1,CYFIP2,ARPC1A,PSMB9,PSMB3,MAPK3,PSMC4,WAS,ELMO1,RPS27A,TAB2,PSMD8,LIMK1,PSMD3,PPP3R1,ACTB,MAPK1,PSMC1,HRAS |
| 8.533e-06 | -11.67 | GO_ESTABLISHMENT_OF_PROTEIN_LOCALIZATION_TO_MEMBRANE | MSigDB lists | GO_ESTABLISHMENT_OF_PROTEIN_LOCALIZATION_TO_MEMBRANE | 259 | 66 | 17377 | 2626 |
SYS1,RPLP2,RAB11B,ANK3,RPL11,SSR1,RPL23A,MOAP1,ATG3,SRP72,RPL29,RPL35,RPL38,EZR,NUP155,ICMT,RPS9,RPSA,OPTN,RPL37,TRAM2,HSPA4,PEX5,CHMP4A,SEC61A1,RPS27A,RPS14,RPLP1,CHMP4B,ROCK1,FAU,SMURF1,TSPAN5,RPS26,PARD3,RPS15,RPS2,FLOT1,NKD2,NUP54,RPL15,WRB,RAB11A,ATG4A,RPL17,ARL6IP1,RPL19,TMED2,PACS2,GCC2,RPS10,RPL6,RPL8,RPS24,SSR2,PACS1,RAB3IP,MACF1,RPL27A,RPL36,GOLGA4,RPL32,GOLGA7,NSF,FAM126A,ASNA1 |
| 8.570e-06 | -11.67 | REACTOME_NGF_SIGNALLING_VIA_TRKA_FROM_THE_PLASMA_MEMBRANE | MSigDB lists | REACTOME_NGF_SIGNALLING_VIA_TRKA_FROM_THE_PLASMA_MEMBRANE | 133 | 40 | 17377 | 2626 |
TSC2,RPS6KA1,RAF1,MEF2A,AKT1S1,MAPK14,PRKACA,FOXO3,CALM2,RAP1A,MDM2,SHC1,PTEN,RALB,PIK3R2,ADCY9,DNM2,CDKN1B,AP2B1,CREB1,STAT3,DNAL4,ADCY7,MLST8,PDPK1,NRAS,RHOA,MAPKAPK3,AKT2,PRKAR1B,KRAS,RIT1,ELK1,MAP2K2,MAPK3,PPP2CA,DUSP3,MAPK1,HRAS,AP2S1 |
| 8.571e-06 | -11.67 | GO_TRANSCRIPTION_FACTOR_ACTIVITY_PROTEIN_BINDING | MSigDB lists | GO_TRANSCRIPTION_FACTOR_ACTIVITY_PROTEIN_BINDING | 567 | 124 | 17377 | 2626 |
ZNF296,MAX,TRERF1,MAGED1,SMARCA4,IRF3,TAF6L,SND1,RCOR3,BIRC2,PARK7,MXD1,SAP130,SP100,JAZF1,MTA1,LPIN2,GMEB1,NOC2L,TAF5L,CRY2,ECD,ATF2,SMARCE1,CCAR1,CARM1,RLIM,SAP30,RYBP,POU2AF1,ERF,PBXIP1,GABPA,EID1,DRAP1,WBP2,HTATIP2,BRCA1,EDF1,USP22,SOX4,CBFB,TRIM28,USP21,DDX17,TAF2,TONSL,HIPK2,ARNTL,PQBP1,ATF6,TRIM32,NCOA1,TFDP2,BEND6,SMAD4,CBX4,POU3F2,SLC30A9,NCOR2,MECP2,TCF3,NACA,MED13L,CTCF,MEF2A,PAWR,PMF1,NOTCH2,MXD4,THRAP3,SUPT7L,PSMD9,ARID1B,JMY,GTF2F1,WWP2,TFAP4,RB1,SUB1,MED8,MED10,HDAC7,BUD31,BRD7,CREB1,MAML1,ZNF710,CITED2,NCOA2,MED22,DCAF6,KAT2A,CREG1,ZMYND11,MTA2,LDB1,RFXANK,RCOR1,ARID1A,CBFA2T2,PRMT2,RXRB,PFDN5,SERTAD2,PDLIM1,GPS2,ZHX1,SETD3,TFDP1,PITX1,NFIL3,TBPL1,PML,PIAS2,SIAH2,DDX5,TAF12,YY1,NR2F2,RNF14,TOB1,N4BP2L2,SMARCD1 |
| 8.574e-06 | -11.67 | positive regulation of RNA biosynthetic process | biological process | GO:1902680 | 1452 | 279 | 17256 | 2622 |
ZNF496,H2AFZ,CXXC1,HEXB,CCNL2,EDRF1,PARK7,GLMP,USF1,NOL11,DNM2,ECD,SENP1,CDC5L,KLF10,AATF,GABPA,TOPORS,USP22,CBFB,ARF4,DOT1L,HHEX,SMAD2,RPS27A,AXIN1,OGT,RNASEL,TFDP2,SMAD1,E2F2,NMD3,HDAC2,DDX58,HIVEP3,HSPH1,PRKAA1,DHX9,EZH1,PSMD9,PSEN1,CDC73,DDRGK1,TFAP4,FOXN2,MYDGF,NUP85,FOXK1,MTA2,MYBL2,BCLAF1,EXOSC9,ARID1A,ADRB2,ELK1,KDM3A,MAP2K2,SERTAD2,ETS2,SETD3,RBMX,PIAS2,PPP3R1,CEBPG,YY1,MAP3K5,RNF14,CDK2,EGLN1,RHOG,KARS,TRERF1,IVNS1ABP,RPS6KA1,RAF1,MAGED1,CREBL2,APP,CCNA2,SHC1,SP100,GMEB1,LPIN2,MAVS,RBM15,ATF2,CDK12,RPRD1B,PSRC1,BRD4,KAT7,WBP2,E2F3,EDF1,MEF2D,TRIM28,SUPT16H,DDX17,TAF2,VEZF1,SAFB,HIPK2,STAT1,ATF6,ATMIN,POU3F2,MECP2,TCF3,ABHD14B,WDR5,BLM,ETS1,FOXO3,MAD2L2,WWP2,GTF2F1,CCNK,PRDM4,CARF,CITED2,CREB1,NCOA2,PPP3CA,KAT2A,ILF3,RFXANK,ZP3,KLF6,PICALM,FADD,GPS2,PITX1,TFDP1,PML,HMGB2,DDX5,CD81,USF2,YWHAH,RORB,CCNC,ZBED3,ZNF76,IER2,HNRNPAB,THOC1,AGRN,KMT2E,GPBP1L1,AAMDC,SIRT2,MAPK14,CREM,TET3,GLIS2,ZNF639,ETV6,PIK3R2,MYBL1,ARID4A,CARM1,ELOF1,RYBP,SP3,DEAF1,NCK1,VHL,MRPL12,UBE2V1,LRP5,BRCA1,EAF2,SOX4,USP21,UBTF,PAF1,E2F4,ZNF268,CHEK2,DVL1,PSMC1,ZNF564,PPP1R12A,CHCHD2,CTCF,MEF2A,CDK13,PPP3CB,THRAP3,RLF,CRLF3,ASXL2,ARID1B,RB1,SUB1,NFATC3,MLX,MED10,SSBP3,ZNF746,CTR9,ICE2,YBX1,MDFIC,MAML1,ERLIN1,LDB1,UTP15,RTF1,NFATC2IP,EIF2A,IRF5,RXRB,CAND1,PSMC4,TBPL1,NLRC5,NUP62,ZFP90,RUVBL2,SMARCD1,TCF12,ASH1L,FOXM1,PLAGL2,SMARCA4,IRF3,PCBP1,NRF1,RRN3,PIN1,TARDBP,F2R,DVL2,MOSPD1,POU2AF1,NFATC2,RBL1,SCAP,STAT6,ARNTL,NCOA1,AKNA,MAPK1,SMAD4,NAT14,SLC30A9,BCL2L12,DNAJC2,EYA1,AGO2,KLF13,HMGN3,NKRF,PAGR1,IRF4,BRD7,ARHGEF2,SS18L1,STAT3,TGFB1,HMGN1,DCAF6,HMGN5,PRKDC,PRMT2,MEN1,TFEB,MAPK3,ATAD2,TFE3,E2F1,KMT2B,PKD2,RBPJ,ZMIZ1,NR2F2,HRAS,IFI16 |
| 8.611e-06 | -11.66 | V$E2F_03 | MSigDB lists | V$E2F_03 | 229 | 60 | 17377 | 2626 |
POLA2,H2AFZ,REPS2,ZCCHC8,RAB11B,PRKCSH,RMI2,CTCF,ORC1,STMN1,ASXL2,FBXO5,RPA2,RNF121,SMC3,INTS7,DPYSL2,PDS5B,ANP32A,NUP153,KNTC1,PCYT2,MCMBP,ANKHD1,DNMT1,ARID4A,LUC7L2,YTHDC1,EIF5A,PPP1R9B,NASP,PRKDC,E2F3,DNAJC9,SLBP,CDC6,SMC2,PKMYT1,NUTF2,MCM2,EIF4G2,MAT2A,SRSF1,HMGN2,PRIM1,DDX17,CAND1,SUGP1,ATP6V1D,ATAD2,RBL1,DCK,ZNF367,E2F1,ATE1,ANP32E,FKBP5,BTBD10,RBBP4,SASS6 |
| 8.611e-06 | -11.66 | V$NRF1_Q6 | MSigDB lists | V$NRF1_Q6 | 229 | 60 | 17377 | 2626 |
INTS2,POLA2,CHMP2A,PPP1R12A,ADAM10,NF1,PPP1R15B,MECP2,MRI1,MAGED1,C16orf87,CDK2AP2,ADO,CNTROB,SND1,PDXDC1,CD320,GTF2F1,PTPN2,ZNF428,KDM2A,PPME1,SEC24C,FUT8,POP7,TECR,DNMT1,ZNF800,FGFR1OP2,CFL1,SMC4,PREB,EIF5A,USO1,RHOA,HSDL1,NARF,RTF1,DNAJA1,CBFB,ARMC8,TRIM28,SMAP2,SRSF1,RXRB,EIF3K,MAGED2,RAB18,ATP6V1D,PALB2,TTLL4,COX7A2L,ATXN2L,CENPBD1,PLOD3,SNRNP70,ARRB2,USF2,PDCD2L,ATXN7L2 |
| 8.616e-06 | -11.66 | BLALOCK_ALZHEIMERS_DISEASE_INCIPIENT_DN | MSigDB lists | BLALOCK_ALZHEIMERS_DISEASE_INCIPIENT_DN | 161 | 46 | 17377 | 2626 |
ZNF207,HSPH1,CSNK2A1,MEF2A,SUPT7L,AP3S1,REEP5,SDHA,WRB,PIP5K1C,CD59,DNAJC8,ATP2A2,UTP18,AHSA1,ATIC,NSFL1C,TTC3,RPN2,ACAD8,PDIA6,PPA1,CSNK1G3,CCT2,DEAF1,PPP3CA,RB1CC1,DRAP1,PGS1,RPL6,RPL38,DNAJA1,TMEM147,PDHX,ECH1,ZFR,GNAS,SEC31A,RAD51C,CDC27,TFDP1,COX7A2L,MPV17,PPP3R1,DDX5,ZMAT3 |
| 8.624e-06 | -11.66 | PSMA7 (proteasome subunit alpha 7) | protein interactions | 5688 | 112 | 37 | 17029 | 2761 |
CYLD,CUL1,POMP,APP,RAD23A,ABL2,RB1,PSMD2,MDM2,PSMD1,PSMA6,HUWE1,UCHL5,RBM3,MAVS,PLK1,TIMP2,PSMA8,RAB7A,CUL3,PSMB7,PSMA1,PSMG1,EXOSC9,SYVN1,BRCA1,MCM2,PSMB9,PSMB3,ISG15,PSMC4,PSMD3,PSMD8,MAPK6,PPP3R1,PSMC1,TERF1 |
| 8.659e-06 | -11.66 | REACTOME_NONSENSE_MEDIATED_DECAY_ENHANCED_BY_THE_EXON_JUNCTION_COMPLEX | MSigDB lists | REACTOME_NONSENSE_MEDIATED_DECAY_ENHANCED_BY_THE_EXON_JUNCTION_COMPLEX | 106 | 34 | 17377 | 2626 |
RPS15,RPS2,RPLP2,GSPT2,RBM8A,RPL15,RPL11,RPL23A,EIF4A3,RPL17,RPL19,UPF2,PABPC1,RPL29,RPL35,RNPS1,RPL8,RPL38,RPL6,RPS10,RPS24,RPL27A,RPS9,RPSA,RPL36,RPL37,PPP2CA,RPL32,RPS27A,RPS14,RPLP1,SMG9,FAU,RPS26 |
| 8.659e-06 | -11.66 | DITTMER_PTHLH_TARGETS_UP | MSigDB lists | DITTMER_PTHLH_TARGETS_UP | 106 | 34 | 17377 | 2626 |
IMMT,H2AFZ,UROD,CDCA3,FLOT1,KLC1,CYCS,PAIP1,RAB8A,RAB4A,ANXA5,CDC25B,CDK12,SRSF10,GPX4,RBX1,RNPS1,VDAC2,LRP5,CAPZA2,GALNT7,RAB22A,RHEB,ARF4,MFN2,NUCB1,ATP1A1,TIMM17A,AP1S1,SRSF3,B4GALT3,UBE2C,AP2S1,ANXA11 |
| 8.764e-06 | -11.64 | GSE6674_UNSTIM_VS_ANTI_IGM_STIM_BCELL_UP | MSigDB lists | GSE6674_UNSTIM_VS_ANTI_IGM_STIM_BCELL_UP | 147 | 43 | 17377 | 2626 |
OTUD5,GOLIM4,PDAP1,RHOC,HEXB,SMC6,NUF2,NCKAP1,COPB2,FERMT3,HERC3,TBC1D22A,RAB35,IL6ST,UBA5,ZDHHC13,PTPN11,ECD,PIK3IP1,CLTB,AHCYL1,ERMP1,SNX2,VHL,CPOX,CYP20A1,SMU1,SCFD2,ZFAND5,ARHGAP15,ALG3,PON2,CDC16,PLAA,FBXO28,TTC13,NSF,SNAP29,ARNTL,FN3KRP,AP2S1,N4BP2L2,FUBP1 |
| 8.767e-06 | -11.64 | GSE2197_IMMUNOSUPPRESSIVE_DNA_VS_UNTREATED_IN_DC_UP | MSigDB lists | GSE2197_IMMUNOSUPPRESSIVE_DNA_VS_UNTREATED_IN_DC_UP | 185 | 51 | 17377 | 2626 |
HIVEP3,COX15,FEZ2,TXN,TMEM184B,B4GALT5,FAM129A,ARID5A,CHIC2,HMGN3,SNN,RGS2,SLC12A9,CRLF3,PMVK,CUTC,BIRC2,ANKIB1,RGS1,PHC2,PTPN2,PDCD10,TIMM23,MBD2,TANK,LPIN2,TIMELESS,PPA1,ARID4A,ENPP4,ADAM17,FAM172A,DDX24,BIRC3,POLR2G,CSRP1,BTAF1,USP42,TOP3A,UTP3,LY6E,RAB22A,RHBDF2,SOCS7,PI4K2A,KEAP1,CCDC86,CCDC6,MAFK,MRPL27,CSNK1D |
| 8.767e-06 | -11.64 | GSE15330_MEGAKARYOCYTE_ERYTHROID_VS_GRANULOCYTE_MONOCYTE_PROGENITOR_IKAROS_KO_DN | MSigDB lists | GSE15330_MEGAKARYOCYTE_ERYTHROID_VS_GRANULOCYTE_MONOCYTE_PROGENITOR_IKAROS_KO_DN | 185 | 51 | 17377 | 2626 |
RHOG,CDS2,LIME1,AGTRAP,DCAF15,GNPDA1,UBXN1,CIB1,TMEM109,KLF13,RACGAP1,NCKAP1,MAPK14,NPLOC4,FANCI,PRNP,FKBP1A,NEK6,RALB,DDA1,ANP32A,ABCD1,CLDND1,TAGLN2,TIPARP,SAP30L,FRMD8,PREB,SEPT9,KLF10,LRBA,MYBL2,MTMR6,EMP3,PLEC,VKORC1,STK17B,ERC1,ASF1B,PDCD6,SERF2,SEC61A1,ARAP1,PIAS2,ADAM9,SSNA1,SMAD1,PLOD3,TSPAN5,LONP2,VPS29 |
| 8.767e-06 | -11.64 | GSE41867_DAY6_EFFECTOR_VS_DAY30_EXHAUSTED_CD8_TCELL_LCMV_CLONE13_DN | MSigDB lists | GSE41867_DAY6_EFFECTOR_VS_DAY30_EXHAUSTED_CD8_TCELL_LCMV_CLONE13_DN | 185 | 51 | 17377 | 2626 |
BCCIP,RMND5A,TBC1D12,TRMT6,JMJD6,SYNRG,CDC73,UBXN2A,NUS1,IARS,THAP4,HUWE1,CD3EAP,UCHL5,DNAAF2,SLC44A1,ATP13A3,ZBTB22,TARDBP,PRADC1,LMAN1,STRAP,TMED2,VPS13B,RPAP3,MAPRE2,CREG1,GABPA,FAM118B,DENND4C,NSUN2,PCGF6,LRRC8A,EML4,RDH11,ADSS,DTWD1,TMEM184C,SYNCRIP,CCDC86,STT3A,ZHX1,ZNF330,MAPK6,GLG1,BCL7C,PGRMC1,SLC16A1,BEND3,CDK2,SSRP1 |
| 8.767e-06 | -11.64 | GSE27786_CD8_TCELL_VS_NKCELL_DN | MSigDB lists | GSE27786_CD8_TCELL_VS_NKCELL_DN | 185 | 51 | 17377 | 2626 |
WASF2,TSC2,TMBIM4,RAF1,TOR1AIP1,TRAK1,CUL1,KLC1,HMGN3,SDF2L1,PRKACA,TMCC3,TMEM179B,RB1,ATP6V0B,TNS3,PRKD3,CCNA2,ZNF326,CAPZA1,PRC1,BRI3,ARHGEF2,ANP32A,MAVS,LPCAT1,CFL1,TRAFD1,LONRF3,SNX2,HELB,ERLIN1,PLEKHM3,RIT1,PTTG1IP,RFC2,MKNK1,TRAM2,GOLGA7,RBM47,OSBPL8,CDCA5,KBTBD7,PTAR1,SEL1L,ACTB,YWHAZ,PSAP,RTN3,NAA60,NXT2 |
| 8.788e-06 | -11.64 | Deubiquitination | REACTOME pathways | R-HSA-5688426 | 301 | 79 | 10287 | 1696 |
USP7,TOMM20,CYLD,ATXN3,INO80E,USP48,BECN1,STAM,BIRC2,USP5,RAD23A,MDM2,PSMD1,BABAM2,CCNA2,PSMA6,ABRAXAS2,UCHL5,RAD23B,JOSD1,MAVS,USP34,BIRC3,PSMA8,VDAC2,PSMB7,BRCA1,USP22,VDAC1,KDM1B,PSMB9,USP21,IDE,SMAD2,RPS27A,PSMD8,AXIN1,PSMD3,OGT,ACTB,USP11,SMAD1,ARRB2,PSMC1,SMAD4,USP13,DDX58,OTUD5,CLSPN,BABAM1,ASXL2,PSMD9,WDR48,MAT2B,PSMD2,CCP110,PTEN,AXIN2,RNF135,ZRANB1,TGFB1,RHOA,KAT2A,FOXK1,TNFAIP3,USP42,PSMA1,USP10,OTUD3,ADRB2,RHOT1,PSMB3,PSMC4,HGS,KEAP1,SIAH2,USP20,MBD6,YY1 |
| 8.821e-06 | -11.64 | GO_FOUR_WAY_JUNCTION_DNA_BINDING | MSigDB lists | GO_FOUR_WAY_JUNCTION_DNA_BINDING | 15 | 10 | 17377 | 2626 |
RAD51C,MECP2,XRCC2,MSH2,XRCC3,HMGB2,MEN1,YY1,RAD51D,MSH6 |
| 8.821e-06 | -11.64 | GO_REGULATION_OF_EXIT_FROM_MITOSIS | MSigDB lists | GO_REGULATION_OF_EXIT_FROM_MITOSIS | 15 | 10 | 17377 | 2626 |
TGFB1,PPP1R9B,BIRC5,PHB2,CDCA5,KNTC1,SIRT2,ANLN,CDC23,UBE2C |
| 8.824e-06 | -11.64 | GO_VACUOLAR_PART | MSigDB lists | GO_VACUOLAR_PART | 656 | 140 | 17377 | 2626 |
RAB14,AGRN,ABCC10,HEXB,GYG1,MAP1LC3B,BECN1,RUFY1,PCYOX1L,NAPG,RAB8A,RAB35,AP1M1,AP2B1,ZFYVE27,MARCH2,DRAM2,WDR41,MIOS,ATG9A,SLC17A5,RAB5B,RAB22A,RHEB,PLEKHF2,AHNAK,WDR11,RPS27A,NAGLU,ATP6V0C,VPS4A,CLN3,ATP6V0E1,STARD3NL,UBE2D3,DNAJC5,GGA1,HLA-E,CCZ1,SDC2,RAB23,LAMTOR3,ACAP1,ASAH1,MAN2B1,PSEN1,TMEM165,VPS25,GNS,VMP1,ZNRF2,SNX18,ATP6V0A2,TMEM8A,PIKFYVE,ATP6V0D1,GBA,APPL1,RHOB,PI4K2A,SCARB2,OSBPL11,NSF,APPL2,CTSA,EHD4,HEXA,SNX14,ANKRD27,CHMP2A,SNX27,GNPNAT1,RAB11B,RAC1,VTI1A,RRAGC,AP1B1,ATP6V1B2,APP,GNB2,STAM,CD320,ATP6V0B,RAB21,SHC1,MTMR4,WDR44,CLCN6,RPN2,TMEM9,TMBIM1,GM2A,ATP6V1G1,SNX8,SNX25,CLCN3,PPT1,RAB7A,GOPC,ATP6V0A1,CHMP2B,AP4E1,CHMP4A,TAB2,AP1S1,CHMP4B,TICAM1,SCARB1,AP2S1,GOLIM4,ANXA6,MANBA,FLOT1,VPS45,GGA2,RAB11A,SCYL2,HLA-A,TFRC,SPPL2A,CTSS,TPCN1,ACP2,GALC,SNX2,RFFL,SPPL2B,NEU1,SH3GLB1,HLA-B,HGS,SGSH,ATP6V1D,CCZ1B,SNAP29,PML,PSAP,ATP6V1C1,CHMP7,VPS29 |
| 8.842e-06 | -11.64 | HSPA4 (heat shock protein family A (Hsp70) member 4) | protein interactions | 3308 | 339 | 86 | 17029 | 2761 |
KARS,CYLD,ST13,NQO1,RAF1,XIAP,OLA1,CUL1,CSNK2A1,USP39,SDHA,APP,PARK7,PRNP,TERF2IP,PA2G4,RAP1A,MDM2,KMT5C,TARDBP,TP53BP2,DNMT1,PLK1,CCT2,VHL,CUL3,EZR,ATXN1,WDR82,MCL1,BRCA1,DNAJA1,RPSA,BRMS1,DNAJC10,SMAD2,LIMK1,PPM1G,KPNA2,FKBP5,MBOAT1,TRIM32,PPP5C,TUBB,HDAC2,BCL2L12,HSPH1,UNK,DNAJC5,AGTRAP,CHTF18,DNAJB2,PRKAA1,JMJD6,DNAJB1,CDK11B,CSNK1A1,CDC73,FGFR3,GART,CTNNBL1,HUWE1,H2AFY,TAGLN2,PPP6R1,TERF2,RPAP3,TELO2,GBA,RCOR1,KCNQ1,TOMM40,PCGF1,MEN1,ISG15,CAND1,XRCC5,KPNA1,SEC23IP,HSPBP1,MAP3K5,YY1,CDK2,TERF1,FAF1,CDKN2A |
| 8.866e-06 | -11.63 | SFXN1 (sideroflexin 1) | protein interactions | 94081 | 60 | 24 | 17029 | 2761 |
COX15,STAU1,TOMM20,EWSR1,TXN,SUZ12,TAP1,ILF3,NDUFA4,VDAC1,SDHA,MYEF2,SSR1,UBA5,ZNF746,PGRMC1,ACAT1,XRCC3,ATP5F1A,APOOL,CLN3,ATF2,TMEM14C,TIMM50 |
| 8.866e-06 | -11.63 | FGF3 (fibroblast growth factor 3) | protein interactions | 2248 | 60 | 24 | 17029 | 2761 |
CDKN2AIP,RPS2,FAM207A,URB2,NOL8,YTHDC2,ZNF574,GTPBP4,EBNA1BP2,UTP3,DHX57,DNAJB9,CENPU,NSA2,FGFR3,NUCB1,TMED10,ZNF689,NOC2L,H2AFX,DUSP11,PDCD11,ANKHD1,DDX52 |
| 8.872e-06 | -11.63 | mitotic DNA integrity checkpoint | biological process | GO:0044774 | 110 | 35 | 17256 | 2622 |
CLSPN,TOP2B,CCNB1,BLM,CNOT11,FANCI,CNOT3,RFWD3,RPA2,PCNA,MDM2,CENPJ,MSH2,GTSE1,CDKN1B,CNOT6L,ATF2,CARM1,PLK3,PRKDC,BTG2,TAOK1,MRNIP,SOX4,CNOT9,RPS27A,E2F4,TFDP1,PML,E2F1,CNOT6,CHEK2,TFDP2,ZNF830,CDK2 |
| 8.890e-06 | -11.63 | REACTOME_RNA_POL_II_TRANSCRIPTION | MSigDB lists | REACTOME_RNA_POL_II_TRANSCRIPTION | 93 | 31 | 17377 | 2626 |
SRSF11,CTDP1,CDC40,POLR2I,POLR2G,POLR2L,POLR2K,SNRPB,SRSF6,RBM8A,RNPS1,POLR2D,SLBP,SRSF5,SNRPD3,POLR2A,GTF2F1,SRSF1,SUPT16H,PAPOLA,ZNF473,POLR2J,SRSF4,SRSF3,SNRPG,TAF12,TCEA1,GTF2H2,TAF6,SSRP1,CSTF1 |
| 8.891e-06 | -11.63 | small molecule binding | molecular function | GO:0036094 | 2448 | 449 | 17224 | 2647 |
RAB14,ABCC10,TAP1,DHX8,GLUD1,UBE2I,OAT,EEF2K,KIFC1,CDK5,NEK6,CYB5RL,RAB4A,ATP13A3,PDS5B,DNM2,UPRT,SUCLG2,CRY2,MAST2,PLCL2,DNMT1,PLK3,RHOBTB3,NRAS,OSBP2,AKT2,PBK,KIF15,MKI67,DDX20,SMC2,AURKB,MCM2,RFC2,RAB22A,RAB2B,ARF4,MAP3K4,MKNK1,KIF18B,LIMK1,MYO18A,DHTKD1,RNASEL,LONP2,PFKP,DDX42,DDX58,HSPH1,RECQL,MUT,CHTF18,RHOC,TRIO,GSPT2,PRKAA1,DHX9,RRM1,RAB23,CERK,KIF23,TOP2B,EIF2AK4,PDXDC1,RTKN,DDX56,CEP104,SMC3,MCM5,EFTUD2,CTPS1,MSH2,DAPK1,RTCB,PIKFYVE,GNAI2,PHKG2,UBE2QL1,CARS2,DDX28,COQ8A,MAPKAPK3,DHX29,NOA1,PGS1,TYW1,GTPBP4,PIP4K2C,SEPT8,RIT1,PKM,MTR,ABCF1,MAP2K2,CCT8,RHOB,PI4K2A,XRCC5,CAT,ADSS,EPRS,HSPBP1,NSF,CSK,CSNK1G1,DCK,QARS,ACLY,MDH1,MAP3K5,CDK2,NRBP1,ACSF2,ZC3HAV1,EGLN1,RHOG,KARS,ABCA3,TP53RK,RAB11B,RPS6KA1,UBR2,RAF1,CHD1L,KIAA0232,RAC1,ACTR3,OLA1,TPX2,MYH9,EFL1,PRKACA,SDHA,CBWD5,CD320,FLAD1,DECR1,RAB21,PRKD3,ATP2A2,RALB,UBA5,ADCY9,CLCN6,SEPT11,TAP2,AQR,TALDO1,GPD1L,ARL5A,CDK12,ADCY7,CCT2,ULK3,ATP13A1,IDH3A,MAP4K4,TAOK1,POLR2D,VDAC2,PFKFB3,GALK2,PKMYT1,DNAJA1,RAB1A,MAT2A,DHX57,DDX17,KIF2A,RAD51C,HSPA4,JAK1,HINT1,RAB24,GUCY1B1,HIPK2,NT5C3B,CBWD1,PDXK,PPP5C,CSNK1D,TUBB,DYNC1LI2,RHEBL1,PRPF4B,POLQ,GALK1,ANXA6,MANBA,TWNK,MECP2,IP6K2,ATP5F1B,BLM,SPR,PMVK,IFT27,RAB11A,PIP5K1C,SRXN1,ERH,GATC,CBWD2,ARF5,TTLL12,ST8SIA2,MAP3K14,UBE2M,MSH6,SMC4,LDHB,PDPK1,TK1,DDX24,GUK1,NEK7,LDHA,BMS1,RHOT1,DDX39A,GUF1,KIF11,MARK2,MYO1F,SLC19A1,GNA12,KIF18A,POLE,TTLL4,ACOX1,MAPK6,NAXE,ASNA1,DDX5,PSAP,DDX52,DDX47,UBE2E2,ST13,AGRN,YTHDC2,MCCC1,CSNK2A1,UBE2Q1,UBE2Z,ABCB10,KIF2C,SIRT2,CDIPT,MAPK14,PAPOLA,ABL2,RAB8A,RAP1A,CDC42,GOT2,EIF4A3,RAB35,TRMU,XRCC2,KIF22,RP2,EIF5,ABCC5,SRPK2,PLK1,LARS,SNRNP200,SEPT9,HARS,TLK1,CDC6,RAB5B,LSG1,STK17B,DHX15,RHEB,SEPT1,CHD3,IARS2,CRCP,BAZ1B,QRSL1,ACTB,STK11,CHEK2,DHFR2,VPS4A,ROCK1,PSMC1,STARD3NL,SEPHS2,UBE2D3,CDK13,RAB6A,THRAP3,CHKA,UBE2Q2,MBD2,KIF13B,SLC27A4,AHCY,GLE1,ACAD8,ALDH18A1,N4BP2,CSNK1G3,ABCC1,NTPCR,AACS,ERLIN1,NQO2,ACSL3,KRAS,EIF2AK1,MAP4K3,UBE4B,SEPT7,DAPK3,BBS12,MASTL,PSMC4,GNAS,PRPS2,NLRC5,SIL1,RUVBL2,ATP5F1A,EHD4,MYO9A,MBD1,MMACHC,SUCLG1,UGP2,GNPNAT1,MRPL39,PMS2,UCK2,SMARCA4,RRAGC,UCK1,CHKB,ORC1,ATP6V1B2,LYN,TWF2,CHD1,MIEF1,FARSA,PDK2,ZBTB21,IARS,DUS4L,SAR1A,NVL,KIF14,CYB5R1,LMAN1,CHTOP,SCYL3,ACSL5,CLCN3,CGAS,RAB7A,OGDH,KDM1B,ARL5B,MBD3,GFER,RAD54B,DAP3,IDE,ATP1A1,DUS3L,DHX16,CLK3,SCAP,FASTK,STK38,XRCC3,MAPK1,ABCA1,RAD51D,NADSYN1,KIF3B,SHPRH,TOR3A,SCYL1,GNE,SMC6,ARFIP2,ARF1,MYO9B,CDK11B,CSNK1A1,RMI1,SCYL2,PIP4K2A,GFM2,XPR1,WRNIP1,KIF5B,GTPBP3,FGFR3,STARD9,NDUFV1,GART,GRK2,DUS2,ABCD1,DDX31,POLR1B,CAMK2G,MICAL3,MYO5A,RNLS,CSNK1G2,RHOA,PRKDC,HELB,BTAF1,ATP2C1,ABCF2,TUFM,PRKAR1B,NADK2,PNPLA8,RHOT2,CDK11A,TARS,MAPK3,MFN2,DDX23,HSPA1B,RAB18,NEK1,UPF1,ATAD2,OSBPL8,ACADM,NR2F2,IDH3B,PLOD3,RPS6KC1,UBE2C,HRAS,HIPK3,TYW1B |
| 8.896e-06 | -11.63 | GO_SPLICEOSOMAL_COMPLEX_ASSEMBLY | MSigDB lists | GO_SPLICEOSOMAL_COMPLEX_ASSEMBLY | 52 | 21 | 17377 | 2626 |
YTHDC1,SNRNP200,SF3B1,SRSF6,CRNKL1,USP39,SRSF5,SNRPD3,PRPF39,TXNL4A,LUC7L,SF3A2,SRSF1,DDX23,LUC7L3,GEMIN6,SNRPG,LUC7L2,SRPK2,PRPF19,SRSF10 |
| 8.937e-06 | -11.63 | BROMODOMAIN | prints domains | PR00503 | 33 | 13 | 4652 | 473 |
BRD4,ATAD2,BRWD1,KAT2A,BRD2,BRPF3,BAZ2A,BRD7,SMARCA4,BAZ1B,PBRM1,BRD9,BRWD3 |
| 8.954e-06 | -11.62 | MPV17 (MPV17, mitochondrial inner membrane protein) | protein interactions | 4358 | 49 | 21 | 17029 | 2761 |
RPS15,RHOA,NDUFB6,VDAC2,LAMTOR3,NDUFA4,MRPS14,NDUFS7,ATP6V1D,PEX5,HNRNPR,NDUFB4,FAM3C,NDUFB9,UQCRH,NDUFS8,MRPL40,CYB5R1,MRPL11,MRPL13,MRPL32 |
| 8.964e-06 | -11.62 | small nuclear ribonucleoprotein complex | cellular component | GO:0030532 | 69 | 25 | 18223 | 2701 |
SART1,SNRNP200,SNRPB,SF3B1,SF3B6,LSM8,PRPF3,SNRPD3,PRPF39,TXNL4A,LUC7L,SF3A2,SNRPA,PRPF18,SF3B2,DDX23,LSM6,LUC7L3,EFTUD2,PRPF4,SNRPG,GEMIN4,WDR62,SNRNP70,LUC7L2 |
| 9.003e-06 | -11.62 | GO_MICROTUBULE_BINDING | MSigDB lists | GO_MICROTUBULE_BINDING | 190 | 52 | 17377 | 2626 |
ZNF207,KIF3B,MAPRE1,RAE1,KIF23,RACGAP1,KIF2C,MAP1LC3B,RAB11A,TUBGCP2,NEIL2,JAKMIP1,PRNP,KIFC1,DST,KIF5B,STARD9,DPYSL2,KIF13B,KIF14,PRC1,DNM2,ARHGEF2,KIF22,MAST2,OGG1,PLK1,PSRC1,MAPRE2,KIF15,CAMSAP1,TUBGCP5,EZR,NUSAP1,WDR81,KIF11,MACF1,AKAP1,KRIT1,KIF2A,KIF18A,FNTA,GOLGA2,KIF18B,BIRC5,MAP4,LRPPRC,FAM83D,PPP5C,NDE1,REEP4,TERF1 |
| 9.003e-06 | -11.62 | GSE411_WT_VS_SOCS3_KO_MACROPHAGE_IL6_STIM_100MIN_UP | MSigDB lists | GSE411_WT_VS_SOCS3_KO_MACROPHAGE_IL6_STIM_100MIN_UP | 190 | 52 | 17377 | 2626 |
CYTIP,IMMT,TOMM20,GOLPH3L,FOXM1,CHTF18,MDH2,SRGN,CDK2AP2,GNE,CENPF,ARFIP2,FKBP2,TCF19,ABHD14A,KIFC1,ERH,DDX56,PSMD1,ZNF473,SIVA1,PELO,AP2B1,FOXN2,SLC38A10,ALDH18A1,CLTB,MTX2,CLPTM1,GUK1,NSDHL,MAN1B1,PSMB7,MRPS10,NUSAP1,BRCA1,EDF1,SHCBP1,CYB5A,ARF4,HSPA1B,PRIM1,DNAJC10,SLCO4A1,MRPL55,CDCA5,UHRF2,ATP6V0C,NAA20,SLC22A23,EHD4,ESPL1 |
| 9.003e-06 | -11.62 | GSE26727_WT_VS_KLF2_KO_LPS_STIM_MACROPHAGE_DN | MSigDB lists | GSE26727_WT_VS_KLF2_KO_LPS_STIM_MACROPHAGE_DN | 190 | 52 | 17377 | 2626 |
RHOG,CDS2,FEZ2,NUP188,HNRNPAB,IVNS1ABP,URB2,DYNLL1,ADO,PLAGL2,CYCS,ZNF267,SAFB2,PSMD9,MRPL19,PNO1,PRNP,IRF4,SUB1,EIF4A3,ZNF200,TIMELESS,TRA2B,FEM1B,RPN2,SS18L1,RP2,MINPP1,AHCYL1,LPCAT1,SP3,IFRD1,ADAM17,MKLN1,PGGT1B,WDR1,HNRNPF,EZR,PLEC,VDAC1,PRDX1,CAND1,PAF1,PPP2CA,LTBP4,SYNCRIP,HPS5,RNF14,PGAM1,HRAS,SSSCA1,ZBTB24 |
| 9.076e-06 | -11.61 | CCT8 (chaperonin containing TCP1 subunit 8) | protein interactions | 10694 | 169 | 50 | 17029 | 2761 |
UNK,KARS,CYLD,POC1A,RAF1,CUL1,ATP6V1B2,RUFY1,SDHA,APP,PARK7,CDC73,CDK5,RFWD3,RPN1,PSMA6,HUWE1,AHSA1,UBA5,CRY2,FGFR1OP2,PDCL3,NIPSNAP1,CDC5L,MOB4,CCT2,VHL,IDH3A,GBA,CUL3,BRCA1,MCM2,VDAC1,ASB13,TRIM28,PPP2CA,PFDN5,KPNA4,ATP1A1,CAMKMT,PRPF4,XRCC3,ACTB,FUS,WDR76,CDK2,IGBP1,SMURF1,PPP2R2D,TUBB |
| 9.076e-06 | -11.61 | HSP90B1 (heat shock protein 90 beta family member 1) | protein interactions | 7184 | 169 | 50 | 17029 | 2761 |
COX15,PRKCSH,RAE1,CUL1,CSNK2A1,SMARCA4,LYN,SDHA,BIRC2,CDC73,EBP,RFWD3,RPN1,MDM2,PCNA,KLF16,HUWE1,PPME1,ZNF746,UBA5,SUCLG2,RPN2,ATF2,STAT3,TERF2,CDC5L,CCT2,USO1,RAB7A,GBA,CUL3,BRCA1,ADRB2,VDAC1,MCM2,CAND1,DERL1,KPNA4,DDOST,MAPK6,STAT1,SEL1L,H2AFX,XRCC3,ACADM,FUS,CLU,COPS6,CDK2,TERF1 |
| 9.084e-06 | -11.61 | GO_TRANSCRIPTION_COACTIVATOR_ACTIVITY | MSigDB lists | GO_TRANSCRIPTION_COACTIVATOR_ACTIVITY | 290 | 72 | 17377 | 2626 |
MAX,TRERF1,MAGED1,SMARCA4,TAF6L,BIRC2,PARK7,SAP130,SP100,MTA1,LPIN2,GMEB1,TAF5L,ECD,ATF2,SMARCE1,CCAR1,CARM1,POU2AF1,GABPA,WBP2,HTATIP2,BRCA1,USP22,EDF1,SOX4,CBFB,USP21,TRIM28,DDX17,HIPK2,PQBP1,ATF6,TRIM32,NCOA1,SLC30A9,POU3F2,NACA,TCF3,MEF2A,THRAP3,PMF1,SUPT7L,PSMD9,ARID1B,JMY,GTF2F1,TFAP4,SUB1,RB1,BUD31,BRD7,CITED2,MAML1,NCOA2,DCAF6,KAT2A,ARID1A,PRMT2,RXRB,SERTAD2,PDLIM1,SETD3,TFDP1,PIAS2,PML,TBPL1,DDX5,TAF12,YY1,RNF14,SMARCD1 |
| 9.108e-06 | -11.61 | RPL27A (ribosomal protein L27a) | protein interactions | 6157 | 138 | 43 | 17029 | 2761 |
RPS15,RPS2,CYLD,RPLP2,AGO2,DHX9,RPL15,CUL1,EBNA1BP2,DUSP22,RPL11,RPL23A,HNRNPA2B1,EIF4A3,PTEN,SIAH1,HUWE1,RPL17,ZNF746,EXOSC1,RPL19,PABPC1,RPL35,RPL8,RPL38,RPL6,RPS10,BRCA1,MCM2,RPS9,ABCF1,RPSA,ISG15,CAND1,RPL36,RPL32,QARS,RPS14,RPLP1,FAU,CDK2,CD81,RPS26 |
| 9.143e-06 | -11.60 | GO_VESICLE_COATING | MSigDB lists | GO_VESICLE_COATING | 72 | 26 | 17377 | 2626 |
USO1,TRAPPC9,GORASP1,CUL3,MCFD2,RAB1A,SEC16A,PICALM,ANKRD28,CD59,SEC31A,SEC23IP,GOLGA2,NSF,TMED10,SEC24C,PPP6C,AP2B1,PPP6R3,TFG,LMAN1,PPP6R1,AP2S1,CSNK1D,TMED2,PREB |
| 9.225e-06 | -11.59 | SRP-dependent cotranslational protein targeting to membrane | REACTOME pathways | R-HSA-1799339 | 115 | 38 | 10287 | 1696 |
RPS15,RPS2,RPLP2,SEC61G,RPL15,RPL11,SSR1,RPL23A,SEC11A,RPN1,RPL17,RPN2,RPL19,RPL22L1,SRP72,RPL29,SEC61B,RPL35,RPL8,RPL38,RPL6,RPS10,SSR2,RPS24,RPL27A,RPS9,RPSA,RPL36,RPL37,RPL32,DDOST,SEC61A1,RPS27A,RPS14,RPLP1,SPCS3,FAU,RPS26 |
| 9.264e-06 | -11.59 | IVANOVA_HEMATOPOIESIS_INTERMEDIATE_PROGENITOR | MSigDB lists | IVANOVA_HEMATOPOIESIS_INTERMEDIATE_PROGENITOR | 138 | 41 | 17377 | 2626 |
COMMD10,GALK1,TRMT6,VPS45,TMEM97,GTF3A,SDF2L1,SLC35B2,MFSD10,SSR1,C12orf10,RPN1,TNS3,CLUAP1,SNUPN,AP3S2,NAA50,PARL,AHCY,CITED2,ZNF583,NXT1,MAPRE2,MAPKAPK3,TSPAN31,ERLIN1,MRPL12,DDX20,SSR2,LUC7L,PLAA,QARS,DBI,DTX4,MDH1,SPCS3,KLHDC4,SCARB1,PGAM1,PFKP,DDX52 |
| 9.394e-06 | -11.58 | HAHTOLA_MYCOSIS_FUNGOIDES_SKIN_UP | MSigDB lists | HAHTOLA_MYCOSIS_FUNGOIDES_SKIN_UP | 171 | 48 | 17377 | 2626 |
PPIB,RECQL,CKLF,GMFG,SF3B1,SUZ12,TSC22D3,UBE2Z,GLUD1,IP6K2,SAFB2,CUTC,FOXO3,RAPGEF6,ERH,RPN1,ARF5,GEMIN6,UPF2,RBM15,SPTAN1,SP3,SHOC2,MAP4K4,CIRBP,ITM2A,SSR2,SREK1,CAPZA2,SOX4,FXR1,ARPC1A,PSMB3,EIF3A,SUPT16H,STOML2,RBM25,SAFB,YWHAZ,SRSF3,GPI,RBBP4,EHD4,SNRNP70,TMEM14A,RTN3,PDCD4,ANXA11 |
| 9.394e-06 | -11.58 | GSE2770_TGFB_AND_IL4_VS_TGFB_AND_IL12_TREATED_ACT_CD4_TCELL_48H_DN | MSigDB lists | GSE2770_TGFB_AND_IL4_VS_TGFB_AND_IL12_TREATED_ACT_CD4_TCELL_48H_DN | 171 | 48 | 17377 | 2626 |
SART1,DNMT3A,MIF4GD,REPS2,ZFP91,VAV2,TKT,ABHD14B,INO80E,CPNE3,GOLM1,ADD3,NUP210,PTEN,DPYSL2,AKAP8,ANP32A,MRPL48,ERI3,LMAN1,TMEM14C,CAMK2G,TACC3,MLST8,TSHZ1,MAPRE2,PTPN18,KAT2A,PPT1,EIF2AK1,SUMF2,GALK2,MTX1,ICAM2,ASB13,STX16,NDRG3,UBTF,ALDH3B1,WAS,PRPS2,MBOAT1,HMGB2,LTA4H,CHPT1,HEXA,SAT2,FAF1 |
| 9.394e-06 | -11.58 | GSE2770_TGFB_AND_IL4_ACT_VS_ACT_CD4_TCELL_6H_UP | MSigDB lists | GSE2770_TGFB_AND_IL4_ACT_VS_ACT_CD4_TCELL_6H_UP | 171 | 48 | 17377 | 2626 |
UBE2D3,WASF2,USP7,HECA,SMAP1,EWSR1,DCAF15,UROD,PTP4A3,HAUS4,INO80E,DAZAP2,SAFB2,NUP205,CSDE1,HNRNPA2B1,MDM2,MED10,TNFAIP8,CDC42,NT5DC1,DPYSL2,UBA5,AFF1,NFU1,MYBL1,HDHD2,FAM171A1,PPP1R9B,ULK3,LDB1,MKI67,HEBP2,ARID1A,COMMD4,PDE3B,ALKBH6,DDX17,UBTF,WAS,SMAD2,PPP2R5A,DUS3L,QARS,PPA2,COX8A,ACTB,YWHAH |
| 9.395e-06 | -11.58 | GO_DNA_SYNTHESIS_INVOLVED_IN_DNA_REPAIR | MSigDB lists | GO_DNA_SYNTHESIS_INVOLVED_IN_DNA_REPAIR | 68 | 25 | 17377 | 2626 |
RFC3,POLK,RAD51AP1,RMI2,TOP3A,USP10,BRCA1,BLM,RFC2,RMI1,ISG15,MAD2L2,NPLOC4,WRNIP1,RPA1,RPA2,DTL,RAD51C,PCNA,POLE,PALB2,RPS27A,XRCC2,XRCC3,RAD51D |
| 9.441e-06 | -11.57 | ARHGDIA (Rho GDP dissociation inhibitor alpha) | protein interactions | 396 | 104 | 35 | 17029 | 2761 |
RHOG,ATXN3,EWSR1,TXN,HNRNPAB,RHOC,RAC1,XIAP,DHX9,SIRT2,UBE2I,TWF2,RAB11A,VAV1,RAP1A,PCNA,CDC42,DUT,CDKN1B,IMPA2,BAK1,RHOA,CUL3,EZR,ADRB2,COMMD4,FADD,FAS,AHNAK,HINT1,MAPK6,CDK2,TERF1,POT1,PFKP |
| 9.441e-06 | -11.57 | SAP18 (Sin3A associated protein 18) | protein interactions | 10284 | 104 | 35 | 17029 | 2761 |
SART1,COX15,SUZ12,EBNA1BP2,THRAP3,SRRT,PARK7,LMNA,EIF4A3,RPN2,SRSF10,CDC5L,SRSF11,NOL12,ZMYND11,WDR18,SMU1,RNPS1,ARMT1,SRSF5,SEPT7,PCGF1,VDAC1,MATR3,SUPT16H,SRSF1,SURF4,DDOST,NSF,SAFB,PSAP,SRSF3,CDK2,IFI16,SSRP1 |
| 9.441e-06 | -11.57 | NUMA1 (nuclear mitotic apparatus protein 1) | protein interactions | 4926 | 104 | 35 | 17029 | 2761 |
SCOC,MPHOSPH8,SUZ12,DYNLL1,RAE1,SUMO2,PTTG1,BRAP,GMCL1,CDC73,LMNA,TERF2IP,RPA2,SMC3,ABRAXAS2,BANF1,RPAP1,DVL2,TERF2,CCDC57,EIF3L,BRD4,ASPM,RTF1,BRCA1,MATR3,EIF3H,RPA1,EPB41,DVL1,SMURF1,CDK2,TERF1,IFI16,DDB1 |
| 9.497e-06 | -11.56 | CCNF (cyclin F) | protein interactions | 899 | 17 | 11 | 17029 | 2761 |
PSMA6,CCP110,RBX1,SCYL1,MYBL2,CUL1,SLBP,RRM2,NUSAP1,CDC6,CCNB1 |
| 9.504e-06 | -11.56 | MORF_SNRP70 | MSigDB lists | MORF_SNRP70 | 60 | 23 | 17377 | 2626 |
RHOA,ADD1,TACC1,WDR1,EIF3D,SUMO2,SUGP2,NACA,PPIE,RNPS1,PSMA1,UBE2I,EIF4G2,DDX39A,API5,DDX17,RXRB,XRCC5,DNAJC8,CSK,SAFB,CAPZA1,SNRNP70 |
| 9.525e-06 | -11.56 | REACTOME_APC_C_CDH1_MEDIATED_DEGRADATION_OF_CDC20_AND_OTHER_APC_C_CDH1_TARGETED_PROTEINS_IN_LATE_MITOSIS_EARLY_G1 | MSigDB lists | REACTOME_APC_C_CDH1_MEDIATED_DEGRADATION_OF_CDC20_AND_OTHER_APC_C_CDH1_TARGETED_PROTEINS_IN_LATE_MITOSIS_EARLY_G1 | 64 | 24 | 17377 | 2626 |
PLK1,PSMA8,PTTG1,PSMB7,PSMA1,ANAPC2,AURKB,CDC23,PSMB9,PSMD9,PSMB3,PSMC4,PSMD2,PSMA6,PSMD1,CDC16,CDC27,RPS27A,PSMD3,PSMD8,ANAPC7,UBE2C,PSMC1,ANAPC4 |
| 9.525e-06 | -11.56 | MORF_TERF1 | MSigDB lists | MORF_TERF1 | 64 | 24 | 17377 | 2626 |
SNRNP200,SUMO2,RNPS1,STARD7,SEPT7,XPO7,DDX39A,SERP1,POLR2A,RAD23A,KRIT1,XRCC5,EPRS,DNAJC8,HNRNPR,SAFB,CAPZA1,ATXN2L,CS,LRPPRC,NAP1L4,TCEA1,TERF1,SMNDC1 |
| 9.532e-06 | -11.56 | MDH2 (malate dehydrogenase 2) | protein interactions | 4191 | 64 | 25 | 17029 | 2761 |
CYLD,NDUFS1,MDH2,IDH3A,BRCA1,ATP5F1B,SDHA,QSOX2,PARK7,CLNS1A,SDHB,DERL1,PCNA,HUWE1,GOT2,CORO1C,GRSF1,PPME1,CS,FUS,ATP5F1A,CDK2,ATF2,CFL1,NUDC |
| 9.596e-06 | -11.55 | GO_DNA_DEPENDENT_DNA_REPLICATION | MSigDB lists | GO_DNA_DEPENDENT_DNA_REPLICATION | 89 | 30 | 17377 | 2626 |
GINS1,POLA2,RFC3,MCM10,THOC1,PRIM2,HELB,SLBP,TOP2B,CDC6,ORC1,BLM,MCM2,POLG2,RFC2,RPAIN,GINS4,RPA1,PRIM1,PCNA,UPF1,POLE,TONSL,MCM5,RNASEH2A,ZNF830,MCMBP,PURA,SLC25A33,POLQ |
| 9.620e-06 | -11.55 | Mitotic Prometaphase | REACTOME pathways | R-HSA-68877 | 111 | 37 | 10287 | 1696 |
MAPRE1,CENPF,CDCA8,CSNK2A1,NUF2,KIF2C,PMF1,CCNB1,SPDL1,NCAPG,MIS12,SMC3,AHCTF1,NUP107,PDS5B,KNTC1,CENPM,NUP85,SEH1L,SMC4,NUDC,PLK1,TAOK1,RANGAP1,SMC2,AURKB,CENPU,PPP2CA,KIF2A,KIF18A,PPP2R5A,DSN1,BIRC5,CDCA5,CENPT,NDE1,CCNB2 |
| 9.640e-06 | -11.55 | WHITFIELD_CELL_CYCLE_G1_S | MSigDB lists | WHITFIELD_CELL_CYCLE_G1_S | 129 | 39 | 17377 | 2626 |
CLSPN,IVNS1ABP,MRI1,RMI2,RAB23,ARGLU1,ORC1,KIAA1147,DNAJB9,SLC25A36,FLAD1,DTL,PDXP,PCNA,MCM5,MSH2,BRD7,NASP,SLBP,CDC6,KIAA1586,EIF2A,MCM2,CHAF1A,ANKRD10,ATAD2,ACYP1,LUC7L3,ZNF367,CAPN7,CDCA7L,E2F1,FAM122A,ZRANB2,MBOAT1,WDR76,E2F2,HRAS,USP53 |
| 9.666e-06 | -11.55 | RPS12 (ribosomal protein S12) | protein interactions | 6206 | 121 | 39 | 17029 | 2761 |
RPS2,CYLD,EIF3D,RPL15,CUL1,APP,PNO1,RPL11,RPL23A,PSMD2,PSMD1,EIF2S2,RPL17,ZNF746,RPL19,RPL29,RPL35,CUL3,RPL38,RPL6,RPS10,RPS24,BRCA1,MCM2,RPL27A,RPS9,EIF3A,RPSA,RPL36,RPS27A,RPS14,PSMD8,PRDX5,PTPN7,RRS1,FAU,CDK2,SMURF1,RPS26 |
| 9.680e-06 | -11.55 | GO_REGULATION_OF_PROTEIN_STABILITY | MSigDB lists | GO_REGULATION_OF_PROTEIN_STABILITY | 210 | 56 | 17377 | 2626 |
ZBED3,ZNF207,USP7,PPIB,PHB2,CREBL2,CDC73,PARK7,NAPG,MDM2,PDCD10,CDC42,PTEN,SIAH1,PIN1,FBXO7,GTSE1,BCL2,CREB1,IFT46,RNF5,MORC3,CDC37,PLK1,TELO2,CDKN2AIP,CCT2,KAT2A,VHL,PRKDC,GTPBP4,KRAS,TMEM147,SYVN1,SOX4,CCT8,SH3GLB1,HSPA1B,DERL1,TSC1,GOLGA7,PSMD8,PML,SEL1L,QRSL1,CTSA,NCLN,CLU,CHEK2,DVL1,FBXL3,MAPK1,CD81,RNF139,CDKN2A,USP13 |
| 9.680e-06 | -11.55 | REACTOME_SIGNALLING_BY_NGF | MSigDB lists | REACTOME_SIGNALLING_BY_NGF | 210 | 56 | 17377 | 2626 |
TSC2,RPS6KA1,RAF1,MAGED1,RAC1,TRIO,MEF2A,AKT1S1,PRKACA,PSEN1,MAPK14,APH1B,FOXO3,CALM2,VAV1,RAP1A,MDM2,SHC1,PTEN,RALB,PIK3R2,PRDM4,ADCY9,ARHGEF1,DNM2,AP2B1,CDKN1B,ARHGEF2,CREB1,STAT3,DNAL4,MLST8,ADCY7,PDPK1,ADAM17,NRAS,RHOA,AATF,MAPKAPK3,APH1A,NET1,AKT2,PRKAR1B,KRAS,ARHGEF12,RIT1,ELK1,MAP2K2,MAPK3,PPP2CA,DUSP3,RPS27A,MAPK1,AP2S1,HRAS,HDAC2 |
| 9.737e-06 | -11.54 | GSE16266_LPS_VS_HEATSHOCK_AND_LPS_STIM_MEF_DN | MSigDB lists | GSE16266_LPS_VS_HEATSHOCK_AND_LPS_STIM_MEF_DN | 176 | 49 | 17377 | 2626 |
NDUFV2,TP53RK,MZT1,TRERF1,THOC1,GPBP1L1,DYNLL1,GMCL1,RMI1,HEATR5B,FBXO5,PTPN2,SMC3,INTS7,MTMR4,ATG3,GRSF1,TANK,BTF3L4,INTS12,FOXN2,AFF1,ATF2,STRAP,PDPK1,TXNL1,ARHGAP17,NXT1,ZFP64,BIRC3,MBLAC2,PPP1R21,TBRG4,EAF2,PRKRA,RAB2B,NECAP2,KIF2A,SERTAD2,RBM47,WNT5B,DTX4,MEGF9,TRIM32,RGL1,NAA20,FBXL3,EHD4,PDCD4 |
| 9.737e-06 | -11.54 | E2F1_UP.V1_UP | MSigDB lists | E2F1_UP.V1_UP | 176 | 49 | 17377 | 2626 |
POLA2,DNAJC2,PKP4,MCM10,UBN1,IVNS1ABP,KLHL21,UBR2,DBF4,UCK2,RRM1,USP39,INO80E,MAPK14,SLC20A1,PIP4K2A,KIFC1,RB1,GRSF1,SRSF4,LPIN2,ARHGEF1,PRC1,BCL2,PRADC1,CLN6,RBM15,TK1,ERMP1,NASP,PRIM2,E2F3,SLBP,FRAT2,USP10,WDHD1,PACS1,AURKB,SMC2,MPG,GUF1,KIF2A,BOLA3,HSPBP1,KPNA1,SMAD1,USF2,TAF6,DDB1 |
| 9.758e-06 | -11.54 | positive regulation of proteasomal protein catabolic process | biological process | GO:1901800 | 106 | 34 | 17256 | 2622 |
ATXN3,SUMO2,NKD2,SIRT2,UBQLN2,CSNK1A1,PSEN1,BCAP31,ANKIB1,FBXO22,DDRGK1,USP5,RAD23A,MDM2,RNF19A,SOCS5,PLK3,PLK1,LONRF3,RBX1,GBA,EDEM2,PSMC4,HSPA1B,HSPBP1,KEAP1,SOCS4,DVL1,CLU,RNF14,PSMC1,CSNK1D,USP13,RNF114 |
| 9.801e-06 | -11.53 | XRCC3 (X-ray repair cross complementing 3) | protein interactions | 7517 | 156 | 47 | 17029 | 2761 |
COPA,SCAMP3,CHERP,PHB2,SF3B1,CHTF18,COPE,TAP1,PMS2,HDGFL2,APP,KTN1,GLMP,SF3B2,RBM17,HNRNPA2B1,FARSA,DNAJC8,ATP2A2,NSRP1,LTN1,TECR,CCAR1,RNF5,AGGF1,ERLIN1,TOR1AIP2,DNAJA1,ERBIN,CCT8,MTR,EIF3A,DERL1,SLCO4A1,RAD51C,TIMM13,FNTA,PALB2,QARS,IMPDH1,FKBP5,NCLN,ATP5F1A,SNRNP70,ZNF598,RAD51D,GEMIN7 |
| 9.819e-06 | -11.53 | MODULE_397 | MSigDB lists | MODULE_397 | 111 | 35 | 17377 | 2626 |
FOXM1,VAV2,CENPF,PTTG1,MRPS26,TPX2,KIF23,ARFIP2,NUF2,ORC1,NUP205,SAC3D1,ZNF200,CDC25B,DVL2,PLK1,JMJD4,NOL12,MYBL2,ILF3,SMC2,KIF11,SNRPA,ASF1B,SOCS7,SCAP,NRM,CDCA7L,CDCA5,E2F1,H2AFX,CABIN1,EYA2,RAD51D,BYSL |
| 9.843e-06 | -11.53 | GO_CELLULAR_PROTEIN_COMPLEX_DISASSEMBLY | MSigDB lists | GO_CELLULAR_PROTEIN_COMPLEX_DISASSEMBLY | 120 | 37 | 17377 | 2626 |
MRPL9,MRPL42,MRPS15,MRPL39,GSPT2,MRPS26,KIF2C,STMN1,GFM2,MRPL19,MRPL50,KIF14,MRPS27,MRPL34,MRPL54,MRPL40,MRPL48,MRPL11,MRPL21,MRPL32,MICAL3,CFL1,MRPL12,MRPL43,MRPS10,MRPL16,MRPS14,MRPL2,DAP3,KIF18A,MRPL55,KIF18B,CHCHD1,MRPL27,VPS4A,MRPL13,MRPL3 |
| 1.001e-05 | -11.51 | G1/S transition of mitotic cell cycle | biological process | GO:0000082 | 124 | 38 | 17256 | 2622 |
POLA2,MAX,MCM10,GPR132,CDT1,DBF4,CUL1,ORC1,CRLF3,FBXO5,CDKN2C,RPA2,RB1,PCNA,MCM5,PPP6C,CDKN1B,ORC3,CAMK2G,PLK3,PPP3CA,BRD4,PRIM2,NASP,CUL3,RRM2,CDC6,MCM2,PRIM1,RPA1,POLE,E2F4,TFDP1,E2F1,ITGB1,TFDP2,CDK2,CDKN2A |
| 1.004e-05 | -11.51 | GO_DNA_SECONDARY_STRUCTURE_BINDING | MSigDB lists | GO_DNA_SECONDARY_STRUCTURE_BINDING | 24 | 13 | 17377 | 2626 |
RAD51C,RAD18,MECP2,NEIL3,XRCC2,MSH2,HMGB2,XRCC3,YY1,BLM,MEN1,MSH6,RAD51D |
| 1.004e-05 | -11.51 | REACTOME_KINESINS | MSigDB lists | REACTOME_KINESINS | 24 | 13 | 17377 | 2626 |
KIFC1,KIF5B,KIF2A,KIF3B,KIF18A,KIF15,KIF23,KLC1,KIFAP3,KIF22,RACGAP1,KIF2C,KIF11 |
| 1.004e-05 | -11.51 | IIZUKA_LIVER_CANCER_PROGRESSION_G1_G2_DN | MSigDB lists | IIZUKA_LIVER_CANCER_PROGRESSION_G1_G2_DN | 24 | 13 | 17377 | 2626 |
SP3,VEZF1,PPIB,TPD52L2,RPN1,GOLGA4,ATP2A2,SIAH1,ATXN2L,GORASP2,ACTB,UBQLN2,IMPA2 |
| 1.005e-05 | -11.51 | GSE17721_PAM3CSK4_VS_GADIQUIMOD_2H_BMDC_DN | MSigDB lists | GSE17721_PAM3CSK4_VS_GADIQUIMOD_2H_BMDC_DN | 181 | 50 | 17377 | 2626 |
RMND5A,TMED7,DCAF15,TMEM41B,TOR3A,DBF4,EPN1,TM9SF3,SIKE1,ARF1,FOXO3,APP,RHBDD1,CNOT3,ANKRD28,ATP6V0B,GATC,RNFT1,TBC1D14,SSBP3,CLDND1,POLR1B,POLK,IDH3A,SUGP2,HNRNPF,GMFB,ITM2A,NFATC2IP,MEF2D,CAPZA2,ASB13,TAZ,SERP1,MFN2,CDKN2AIPNL,FNTA,FAM3C,PPM1G,NFIL3,ARNTL,ACLY,ZDHHC7,ADAM9,CRCP,NCOA1,CDK2,MAPK1,MRPL3,VPS29 |
| 1.005e-05 | -11.51 | GSE17721_CPG_VS_GARDIQUIMOD_8H_BMDC_DN | MSigDB lists | GSE17721_CPG_VS_GARDIQUIMOD_8H_BMDC_DN | 181 | 50 | 17377 | 2626 |
SRM,PDCD6IP,SCAMP3,CKLF,FAM53C,WDR13,SLC2A1,ABHD14B,IL21R,REEP5,TFRC,PABPC4,ATP6V0B,PRKD3,SMC3,PRDM4,RRBP1,FJX1,ANP32A,RPF2,RBM3,F2R,DNMT1,RPRD1B,EEF1D,TMX1,PBXIP1,PRRC2A,NSUN2,RDH10,WBP2,LNX2,ESYT1,BUD13,CBFA2T2,POLR2A,MAPK3,UTP20,HHEX,EIF4ENIF1,CTBS,MAPK6,ITGB1,GLG1,ADAM9,ARRB2,MRPL3,LRP8,DDB1,ADAM23 |
| 1.005e-05 | -11.51 | GSE38681_WT_VS_LYL1_KO_LYMPHOID_PRIMED_MULTIPOTENT_PROGENITOR_UP | MSigDB lists | GSE38681_WT_VS_LYL1_KO_LYMPHOID_PRIMED_MULTIPOTENT_PROGENITOR_UP | 181 | 50 | 17377 | 2626 |
C19orf53,TMEM203,RAB11B,UCK2,MOGS,GTF3A,MXD4,DAZAP2,RGS2,EIF1B,ZADH2,IL21R,SAC3D1,PIP5K1C,THAP4,GOT2,SEC24C,XRCC2,BUD31,SLC35B4,AXIN2,CRY2,TAF5L,ANAPC7,MAP3K14,LRRC59,ASB6,CTDSP2,SPSB3,MED22,TIMM8B,TMEM115,SIGMAR1,VDAC2,ZNF574,PIP4K2C,C1orf35,FRAT2,PRPF3,SOX4,MEN1,POLG2,ABCF1,PSMC4,CDCA4,AXIN1,PPM1G,HMGB2,ACADM,HRAS |
| 1.005e-05 | -11.51 | GSE21670_UNTREATED_VS_TGFB_IL6_TREATED_STAT3_KO_CD4_TCELL_DN | MSigDB lists | GSE21670_UNTREATED_VS_TGFB_IL6_TREATED_STAT3_KO_CD4_TCELL_DN | 181 | 50 | 17377 | 2626 |
SLC12A7,RMND5A,CYTIP,NADSYN1,C9orf78,ANXA6,SEC61G,CAST,ACTR3,TMX4,HEXB,RAB6A,PRPF39,COMMD8,RPL11,RAP1A,MLX,ADD3,HUWE1,RCSD1,RBM3,TECR,GPD1L,STAT3,SPSB3,SMC4,KDM3B,NCK1,TACC1,RB1CC1,MTA2,PARP4,HERPUD2,SMAP2,DAPK3,ALKBH6,EIF3K,NSA2,TMEM184C,AHNAK,PPP2R5A,RBM25,NSF,PITPNA,YWHAZ,BTF3,PSAP,ROCK1,SMURF1,N4BP2L2 |
| 1.005e-05 | -11.51 | GSE28737_WT_VS_BCL6_HET_MARGINAL_ZONE_BCELL_DN | MSigDB lists | GSE28737_WT_VS_BCL6_HET_MARGINAL_ZONE_BCELL_DN | 181 | 50 | 17377 | 2626 |
KARS,GPR132,TXN,MAX,URB2,SLC41A1,RHOC,MAGED1,CUTA,SLC39A13,CSNK2A1,USP39,GYG1,SNN,OAT,ATP6V1B2,IL21R,MIEN1,KTN1,MXD1,SMC3,UTP18,PRDM4,RNF19A,POLR1B,MAP3K14,ALDH18A1,SNX25,TNFAIP3,ANKRD37,TMEM39A,PARP4,MKI67,NLN,NUP155,EAF2,TANC1,METTL22,RAB22A,ISG15,ZFR,CACNB1,RBM47,MAPK6,BBX,NLRC5,PKD2,MYO9A,PDLIM5,LONP2 |
| 1.005e-05 | -11.51 | GSE17721_4_VS_24H_GARDIQUIMOD_BMDC_DN | MSigDB lists | GSE17721_4_VS_24H_GARDIQUIMOD_BMDC_DN | 181 | 50 | 17377 | 2626 |
SRM,C9orf78,TXN,ST13,IVNS1ABP,DYNLL1,SNX15,STARD7,SUMF1,CDC42SE2,COMMD5,FOXO3,MOAP1,PSMA6,ZNF639,LPIN2,ARL6IP1,CYB5R1,SLC35A1,SRSF10,ACSL5,TDP1,LARS,RHOA,NXT1,KAT2A,ERLIN1,LRBA,SUGP2,PFKFB3,EIF2AK1,TARS,CLNS1A,SERF2,DHX16,VPS26B,STAT6,TULP3,NAGLU,MRPL27,GLG1,USP20,CHEK2,MRPL13,ATP6V0E1,SLC25A39,POT1,NMD3,CBX4,TMEM33 |
| 1.005e-05 | -11.51 | GSE29618_LAIV_VS_TIV_FLU_VACCINE_DAY7_PDC_UP | MSigDB lists | GSE29618_LAIV_VS_TIV_FLU_VACCINE_DAY7_PDC_UP | 181 | 50 | 17377 | 2626 |
WSB2,DNAJC2,GGNBP2,PNISR,ADD1,ZCCHC8,SRSF6,DHX9,CDCA3,STARD7,NANS,SND1,DAZAP2,PDXDC1,HMG20A,RSAD1,TFRC,RALB,ATP13A3,PPP4R1,ACAD8,CPSF4,SGCB,SLC35A1,VOPP1,IFRD1,AGGF1,ZFP64,NSDHL,BTAF1,NARF,TUBGCP5,BOLA1,PRPF3,SRSF5,PTTG1IP,ODC1,SLTM,MATR3,HMGN2,MAN2A2,SUGP1,UEVLD,TIMM17A,LUC7L3,DDX5,TAF12,CHPT1,NGLY1,POT1 |
| 1.010e-05 | -11.50 | G1 DNA damage checkpoint | biological process | GO:0044783 | 72 | 26 | 17256 | 2622 |
PLK3,PRKDC,BTG2,CCNB1,SOX4,CNOT11,CNOT3,CNOT9,RPA2,RFWD3,PCNA,MDM2,RPS27A,CENPJ,E2F4,TFDP1,E2F1,PML,CDKN1B,GTSE1,CNOT6,CHEK2,TFDP2,CNOT6L,CDK2,CARM1 |
| 1.010e-05 | -11.50 | aerobic respiration | biological process | GO:0009060 | 72 | 26 | 17256 | 2622 |
COX15,COX5B,SUCLG1,UQCR10,MDH2,IDH3A,MTFR2,ADSL,NDUFA4,COX4I1,CYCS,OGDH,SDHA,NDUFS7,CAT,SDHB,MTFR1L,COX7A2L,COX8A,CS,DHTKD1,SUCLG2,COX5A,MDH1,UQCRH,IDH3B |
| 1.021e-05 | -11.49 | GO_REGULATION_OF_AUTOPHAGOSOME_ASSEMBLY | MSigDB lists | GO_REGULATION_OF_AUTOPHAGOSOME_ASSEMBLY | 34 | 16 | 17377 | 2626 |
MTMR3,TBC1D12,FEZ2,CHMP4A,RALB,PHF23,RAB7A,TBC1D14,PIP4K2C,CHMP4B,UBQLN2,PIKFYVE,LRSAM1,PIP4K2A,RNF5,SH3GLB1 |
| 1.026e-05 | -11.49 | regulation of cellular protein localization | biological process | GO:1903827 | 479 | 108 | 17256 | 2622 |
RHOG,TXN,CYLD,RAB11B,DYNLL1,ANK3,BCL2L1,PRKACA,SEC16A,MAPK14,BCAP31,PARK7,PRNP,MIEF1,CDK5,MDM2,SP100,RALB,GLIS2,PIN1,PIK3R2,CNPY4,PARL,AP2B1,MAVS,TP53BP2,LMAN1,GPD1L,ZC3H3,SPIDR,TMBIM1,HTRA2,KCNAB2,CHP1,PLK1,PLK3,CCT2,AKT2,GOPC,KAT7,EZR,NUTF2,DNAJA1,EDEM2,TRIM28,USP36,EPB41,IWS1,PPP2R5A,ITGB1,STK11,DVL1,VPS4A,TFDP2,MAPK1,OAZ1,C2CD5,NMD3,NUMB,SVIP,UBE2D3,HSPH1,TM9SF4,CDT1,PRKAA1,NKD2,RAB23,NUP54,CIB1,PSEN1,RAB11A,LMNA,SAPCD2,DDRGK1,KIF5B,RB1,PDCD10,HUWE1,PTPN11,GTSE1,H2AFY,BCL2,ATG13,MDFIC,PDPK1,TGFB1,GCC2,ATP5IF1,ACSL3,RANGAP1,APPL1,PICALM,CCT8,SH3GLB1,NUCB1,PCM1,CSK,OAZ2,TFDP1,CDCA5,E2F1,PPP3R1,NUP62,YWHAZ,RUFY3,YWHAH,NUP58,TERF1 |
| 1.029e-05 | -11.48 | Nup107 (nucleoporin 107) | protein interactions | 103468 | 53 | 22 | 17029 | 2761 |
NDC1,NUP188,RAE1,SUMO2,NUP54,RANGAP1,NUP155,UBE2I,NUP205,KPNA4,AHCTF1,NUP210,NUP107,NUP62,NUP153,GLE1,SMPD4,NUP85,SENP1,NUP58,AAAS,SEH1L |
| 1.029e-05 | -11.48 | GO_TRNA_METABOLIC_PROCESS | MSigDB lists | GO_TRNA_METABOLIC_PROCESS | 162 | 46 | 17377 | 2626 |
CTU2,KARS,TP53RK,MRPL39,TRMT6,LAGE3,C2orf49,GTPBP3,FARSA,EXOSC7,GATC,IARS,DUS4L,GRSF1,TRMU,POP7,UBA5,FBL,CPSF4,PPA1,CARS2,METTL1,RPP25,LARS,GTF3C6,HARS,NSUN2,TYW1,METTL2A,EXOSC9,POLG2,TARS,EPRS,DUS3L,LSM6,QARS,WDR4,TYW5,PPA2,IARS2,FTSJ1,QRSL1,DTD1,OSGEPL1,TSEN15,TYW1B |
| 1.033e-05 | -11.48 | GSE46606_UNSTIM_VS_CD40L_IL2_IL5_1DAY_STIMULATED_IRF4MID_SORTED_BCELL_UP | MSigDB lists | GSE46606_UNSTIM_VS_CD40L_IL2_IL5_1DAY_STIMULATED_IRF4MID_SORTED_BCELL_UP | 186 | 51 | 17377 | 2626 |
DNAJC2,SART1,RECQL,SARNP,RAB11B,ADAM10,RAF1,TMEM109,WDTC1,DHX9,DNAJC24,RAB11A,NPLOC4,KRR1,PPIG,PIK3R2,CDKN1B,FOXN2,ALDH18A1,ZRANB1,RBM15,ATP6V0D1,SMC4,RLIM,RYBP,ENPP4,PPP3CA,TRAFD1,TNFAIP3,EIF2A,SYVN1,SEPT7,PRKRA,MCM2,PPP2R5A,ETS2,PPA2,ATXN2L,FAM83D,KHSRP,FAM122A,HMGB2,MDH1,TCOF1,RRS1,ZNF830,CDK2,CHPF2,ANXA11,LRCH1,NXT2 |
| 1.033e-05 | -11.48 | GSE23308_WT_VS_MINERALCORTICOID_REC_KO_MACROPHAGE_UP | MSigDB lists | GSE23308_WT_VS_MINERALCORTICOID_REC_KO_MACROPHAGE_UP | 186 | 51 | 17377 | 2626 |
SEPHS2,FEZ2,IVNS1ABP,SLC41A1,DCTN2,SNX15,PTTG1,AP3M2,GGA2,FOXO3,SDHA,RGS1,CD320,MTA1,SSBP3,ZNF746,MEA1,AKR1B1,KIFAP3,TPCN1,CTDSP2,KCNAB2,SRPK2,RBM15B,CPNE1,ARHGAP17,POLR2I,SIGMAR1,SLC16A7,WDHD1,CDC6,UBE4B,USP22,POLR2A,MAPK3,TFEB,RPA1,EPB41,GNAS,ADSS,KEAP1,STK38,EXOC4,NCLN,ACADM,CHEK2,PDXK,IDH3B,NAA20,NGLY1,SLC25A39 |
| 1.033e-05 | -11.48 | GSE27786_CD4_TCELL_VS_MONO_MAC_UP | MSigDB lists | GSE27786_CD4_TCELL_VS_MONO_MAC_UP | 186 | 51 | 17377 | 2626 |
MUM1,TAP1,ALKBH5,ENSA,CTCF,ARGLU1,CDK13,NKRF,DCUN1D4,SLC20A1,IL21R,FAM8A1,MYEF2,RBM4,ATPAF1,EBP,ABL2,SNRNP25,CLUAP1,EI24,H2AFY,PTGES3,ZNRD1,SAP30L,RPL22L1,SMC4,CDC5L,PRPF19,TXNL1,GTF3C6,HARS,NSDHL,TEX10,NSUN2,NFATC2,IL12RB1,RAB3IP,AZI2,STK17B,MAK16,CCT8,EIF3A,SOCS7,TRIM47,BRWD1,RPL32,BRD2,CLK3,DCAF11,IGBP1,SMAD4 |
| 1.033e-05 | -11.48 | GSE17721_12H_VS_24H_POLYIC_BMDC_DN | MSigDB lists | GSE17721_12H_VS_24H_POLYIC_BMDC_DN | 186 | 51 | 17377 | 2626 |
TCF12,SNX15,CDCA3,CTCF,B4GALT1,CLCC1,OAT,BRIX1,PITHD1,RNF103,DDRGK1,CSDE1,FAM192A,CEP104,SMC3,NUP210,PTEN,IL6ST,RNASEK,PHTF1,PPCDC,ABCD1,MAVS,ECD,STAT3,TMEM14C,SRSF11,CSNK1G2,RAB7A,NSUN2,WBP2,TUBGCP5,HTATIP2,UHRF1BP1,EIF4H,RHOT2,STK17B,CCT8,CYB5A,POLR2A,MAP3K4,NUCB1,HSPA4,FASTK,ACADM,KLHDC4,IDH3B,TSTD2,NAA60,RAD51D,CCDC137 |
| 1.033e-05 | -11.48 | GSE21063_CTRL_VS_ANTI_IGM_STIM_BCELL_NFATC1_KO_16H_DN | MSigDB lists | GSE21063_CTRL_VS_ANTI_IGM_STIM_BCELL_NFATC1_KO_16H_DN | 186 | 51 | 17377 | 2626 |
CCDC93,TCF12,GPR132,ZCCHC9,GGNBP2,ZCCHC8,DAP,TSC22D3,FAM129A,SMC6,CBLL1,NHLRC3,DOCK11,MAPK14,TRIM65,TFRC,FBXO5,BCAT2,DDRGK1,WWP2,RPL23A,ATG4A,SLC1A4,SUV39H2,IARS,YBX1,MAST2,ECD,FBXL19,SAP30L,MRPL32,PCBP2,PDLIM2,SRSF11,ZNF524,ADAM17,RFC3,GALC,NOL8,RCOR1,KRAS,LUC7L,TARS,EIF3A,CAND1,PFDN5,MBIP,FAM110A,CERS6,ARNTL,ZNF598 |
| 1.033e-05 | -11.48 | GSE24634_NAIVE_CD4_TCELL_VS_DAY3_IL4_CONV_TREG_DN | MSigDB lists | GSE24634_NAIVE_CD4_TCELL_VS_DAY3_IL4_CONV_TREG_DN | 186 | 51 | 17377 | 2626 |
GCLM,IMMT,FOXM1,BCL2L1,FAM136A,SNRPD3,BLM,UBE2I,TMEM165,POLR3K,RMI1,MYL6B,CFLAR,DTL,FANCL,APLP2,PSMD1,AHSA1,SRI,KNTC1,TAGLN2,MRPL11,LRRC59,HTRA2,TACC3,MED22,PREB,CCT2,TIMM8B,AGGF1,MKI67,KIF15,GTPBP4,GORASP2,SMC2,NDUFA7,ICMT,MRPS14,SUPT16H,EPRS,IDE,KEAP1,DHX16,PSMD8,ODF2,H2AFX,RBPJ,PDXK,MAPK1,ESPL1,POLQ |
| 1.033e-05 | -11.48 | GSE3982_MAST_CELL_VS_NEUTROPHIL_UP | MSigDB lists | GSE3982_MAST_CELL_VS_NEUTROPHIL_UP | 186 | 51 | 17377 | 2626 |
TCF12,CCNC,CDC40,SEC61G,GNE,STARD7,NENF,FAM136A,LYRM2,PDXDC1,PSMD1,SIAH1,RNFT1,BANF1,RRBP1,SRI,MRPL34,PIGG,AKR1B1,AP2B1,RPAP1,TTC4,PTGES3,TECR,ERI3,FAM171A1,ILKAP,SEH1L,SOCS5,LARS,AGGF1,DCAF6,ATP13A1,POLR2G,MRPL12,NUP155,MPG,CBFB,MBD3,FKBP3,LSG1,OPTN,AKAP1,GALNT2,DDOST,TPP2,GOLGA8A,ERGIC3,WDR7,YWHAH,PRPF4B |
| 1.033e-05 | -11.48 | GSE25088_IL4_VS_IL4_AND_ROSIGLITAZONE_STIM_STAT6_KO_MACROPHAGE_DAY10_UP | MSigDB lists | GSE25088_IL4_VS_IL4_AND_ROSIGLITAZONE_STIM_STAT6_KO_MACROPHAGE_DAY10_UP | 186 | 51 | 17377 | 2626 |
H2AFZ,TRERF1,CKLF,TMX4,ACAP1,MED13L,CDIPT,LCLAT1,RMI1,BCAP31,CCDC28A,SLC25A37,PAIP2,MAN1A1,APLP2,NFATC3,ADD3,PTEN,PPP4R1,OSTF1,SPTSSA,GNAI2,NCOA2,MSH6,ZDHHC18,ABHD2,ATG9A,KIAA0040,PACS1,BICD2,STX16,MYO1F,MTMR3,HHEX,PRDX3,KBTBD7,MEGF9,CBWD1,DHTKD1,MBOAT1,CABIN1,WIPI2,AKNA,MAP3K5,NDE1,ARRB2,LTA4H,XRCC4,PGAM1,HIPK3,DEF6 |
| 1.033e-05 | -11.48 | GSE12845_IGD_POS_BLOOD_VS_NAIVE_TONSIL_BCELL_DN | MSigDB lists | GSE12845_IGD_POS_BLOOD_VS_NAIVE_TONSIL_BCELL_DN | 186 | 51 | 17377 | 2626 |
DDX47,DNMT3A,NOP2,B4GALT5,ARID5A,MED13L,KLHL18,PPP1R16B,FOXO3,CHD1,KIF5B,IRF4,PA2G4,RBM23,VASP,KDM2A,IL6ST,MTA1,PELO,PRC1,DNM2,RBM3,EIF5,LPCAT1,IFT46,KCNAB2,PPIF,SRSF11,PLK1,ZNF672,MAPRE2,NET1,DENND1B,MYBL2,ILF3,EZR,NUSAP1,ASB13,MAT2A,FBXO21,MTHFD2,KPNA1,DUSP3,SIAH2,SEL1L,H2AFX,CABIN1,MAP3K5,NGLY1,LONP2,TUBB |
| 1.033e-05 | -11.48 | GSE9239_CTRL_VS_TNF_INHIBITOR_TREATED_DC_DN | MSigDB lists | GSE9239_CTRL_VS_TNF_INHIBITOR_TREATED_DC_DN | 186 | 51 | 17377 | 2626 |
HIVEP3,C1orf112,URB2,CENPF,CDCA3,KIF23,CTCF,SUMF1,AGFG1,ASXL2,MYEF2,ARID1B,POLR3K,ARL6IP6,KIFC1,TMEM69,ZNF428,MLX,CCP110,STRBP,HADHB,C8orf59,GPD1L,TACC3,SAP30,GINS1,TTPAL,CYTH1,NASP,SCFD2,MYBL2,CKAP2L,KRAS,BRCA1,MASTL,BRMS1,RAD51C,KIF18A,DGCR8,CERS6,DCK,TBL3,CEP55,ARNTL,WDR4,CDCA5,H2AFX,GAS2,GEN1,BYSL,FAM72A |
| 1.034e-05 | -11.48 | cell death | biological process | GO:0008219 | 1075 | 214 | 17256 | 2622 |
MAX,DDX47,PDCD6IP,TSC2,THOC1,NF1,TMEM109,XIAP,CSNK2A1,CUL1,UBE2Z,MIEN1,BECN1,MAPK14,BIRC2,CDK5,NEK6,GSDMB,SIVA1,ATG3,ETV6,NOC2L,FNIP2,SENP1,DRAM2,CCAR1,TIMM50,RYBP,BAK1,PLK3,PGAP2,AKT2,MCL1,TOPORS,LRP5,EAF2,BRCA1,DIDO1,MCM2,STK17B,OPTN,BRMS1,AXIN1,PRDX5,BCL7C,OGT,STK11,CHEK2,CLU,ROCK1,E2F2,TRAF5,RTN3,ZMAT3,CAPN1,SMNDC1,PDCD4,UBE2D3,CLSPN,GADD45G,DHX9,CDIP1,CIB1,TIA1,MEF2A,CYCS,NOTCH2,NCKAP1,PDCD7,PSEN1,RHBDD1,APOPT1,JMY,CFLAR,RTKN,RB1,TIGAR,DAD1,XPA,EI24,MSH2,DAPK1,ARL6IP1,BCL2,MYDGF,KDELR1,EIF5A,PIGT,NOA1,OXR1,ERO1A,GBA,BCLAF1,UBE4B,PKM,CYFIP2,FXR1,EIF4G2,APPL1,SLTM,RHOB,DAPK3,FAS,FNTA,KPNA1,SIAH2,NUP62,MAP3K5,TMEM14A,ALS2,CYLD,DNMT3A,TRAF7,IFI27L1,RPS6KA1,DYNLL1,RAF1,TPX2,RRAGC,PLAGL2,BCL2L1,IRF3,DUSP22,APP,BCAP31,MOAP1,PDK2,BABAM2,TNFAIP8,SIAH1,RALB,PDCD2,CDKN1B,BCAP29,TP53BP2,ATF2,HTRA2,PDCL3,EBAG9,PPIF,BIRC3,POLR2G,TAOK1,CUL3,HTATIP2,MEF2D,CADM1,VDAC1,PPP2CA,DNAJC10,DAP3,HINT1,FASTK,HIPK2,GADD45B,TICAM1,GAS2,MAPK1,EYA2,USP53,BCL2L12,GCLM,PKP4,NDUFS1,MAGEH1,ANXA6,TMBIM4,CASP6,DAP,SRGN,PAWR,CDK11B,FOXO3,MFSD10,FGFR3,PDCD10,CTNNBL1,PTEN,FEM1B,PACS2,MSH6,PDPK1,TGFB1,TNFAIP3,PRKDC,JTB,PARP4,RFFL,EMP3,PNPLA8,RHOT1,API5,RHOT2,CDK11A,FADD,SH3GLB1,MAPK3,MFN2,CTSL,PDCD6,BIRC5,PRDX3,ELMO1,E2F1,PML,TMEM219,AEN,HMGB2,DDX5,HRAS,ESPL1,HIPK3,FAF1,IFI16 |
| 1.036e-05 | -11.48 | G-rich strand telomeric DNA binding | molecular function | GO:0098505 | 10 | 8 | 17224 | 2647 |
TERF2IP,HNRNPA2B1,RPA2,NABP2,TERF1,POT1,RPA1,TERF2 |
| 1.040e-05 | -11.47 | AIRE (autoimmune regulator) | protein interactions | 326 | 92 | 32 | 17029 | 2761 |
ASAH1,CUL1,SNRPD3,FBXO3,PCNA,SMC3,MCM5,EFTUD2,MSH2,TARDBP,PABPC1,GM2A,MSH6,NASP,RBX1,CREG1,SNRPB,PRKDC,HNRNPF,MCM2,TRIM28,POLR2A,DDX17,SRSF1,GEMIN5,HSPA4,DDX5,RUVBL2,SRSF3,TUBB,HDAC2,SSRP1 |
| 1.041e-05 | -11.47 | MRPS31 (mitochondrial ribosomal protein S31) | protein interactions | 10240 | 72 | 27 | 17029 | 2761 |
NOL12,PPAN,SARNP,RBM42,MRPS2,MRPS15,USP42,RPL6,MRPS26,CUL3,FLOT1,MRPS10,MRPS14,DAP3,HNRNPR,GRSF1,ZNF746,MRPS27,TRMT10B,RBM3,RRS1,SNRNP70,CFAP20,STAT3,ZC3H3,CCDC59,ZC3HAV1 |
| 1.041e-05 | -11.47 | AIMP1 (aminoacyl tRNA synthetase complex interacting multifunctional protein 1) | protein interactions | 9255 | 72 | 27 | 17029 | 2761 |
KARS,COX15,LARS,GCC2,CYLD,TRIR,RPL15,CUL1,BRCA1,DNAJA1,SND1,SNRPD3,MCFD2,RPL27A,MAPK14,APP,OPTN,RPL36,RPL23A,PA2G4,HOMER1,EPRS,IARS,RPL17,CORO1C,QARS,ATP5F1A |
| 1.041e-05 | -11.47 | ZNF2 (zinc finger protein 2) | protein interactions | 7549 | 72 | 27 | 17029 | 2761 |
ZCCHC9,AATF,DDX24,GTPBP4,CTCF,CDK13,BMS1,UTP3,BUD13,BRIX1,MAK16,ZNF121,APP,TRIM28,CENPU,RPL17,RBM34,RPF2,DDX31,RRS1,ZNF770,CDK12,ZNF800,ZC3HAV1,ZNF189,CCDC137,PRPF4B |
| 1.041e-05 | -11.47 | PSMB9 (proteasome subunit beta 9) | protein interactions | 5698 | 72 | 27 | 17029 | 2761 |
POLR2I,POLR2G,POLR2L,PSMA8,POLR2K,ELOA,PSMB7,POLR2D,PSMA1,PSMG1,POMP,PSMB9,PSMB3,POLR2A,PSMC4,FAM192A,PSMD2,PSMD1,PSMA6,POLR2J,UCHL5,PSMD8,PSMD3,FBXO7,NCOA1,PSMC1,NCOA2 |
| 1.041e-05 | -11.47 | NDUFA2 (NADH:ubiquinone oxidoreductase subunit A2) | protein interactions | 4695 | 72 | 27 | 17029 | 2761 |
NDUFV2,PHB2,MRPL43,RPL38,ILF3,OLA1,LAMTOR3,NDUFA4,ABCB10,COX4I1,UBE4B,ATP5F1B,TOMM40,UBE2I,SPR,SDHA,APP,NDUFS4,SDHB,SUGP1,NDUFV1,NDUFA11,PML,NABP2,NDUFB9,NDUFS5,ATP6V0D1 |
| 1.043e-05 | -11.47 | WD40 | pfam domains | PF00400 | 218 | 57 | 17054 | 2545 |
WSB2,CDC40,CORO7,TRAF7,COPA,RAE1,WDR13,POC1A,WDTC1,STRN4,WDR5,GNB2,WDR48,COPB2,DTL,WDR44,FBXW2,TAF5L,CORO1A,UTP4,STRAP,SEH1L,PRPF19,CSTF1,PREB,WDR41,MLST8,DCAF6,DCAF8,WDR1,WDR18,SMU1,UTP15,WDHD1,WDR82,PPWD1,WDR81,ARPC1A,EML4,GEMIN5,PLAA,BRWD1,SCAP,TBL3,CORO1C,WDR59,WDR4,DCAF11,WDR7,PRPF4,DMWD,RBBP4,WDR62,WDR91,BRWD3,DCAF5,AAAS |
| 1.058e-05 | -11.46 | GSE17721_12H_VS_24H_PAM3CSK4_BMDC_UP | MSigDB lists | GSE17721_12H_VS_24H_PAM3CSK4_BMDC_UP | 191 | 52 | 17377 | 2626 |
ZNF207,DNMT3A,RRP15,PHF23,RHOC,CHD1L,TBC1D13,STAM,WRNIP1,VAV1,CAPN2,RNF121,UBXN2A,NEK6,UTP18,ATG3,SOCS6,MRPL54,SEPT11,MRPL11,SGCB,LRRC59,S100A6,ATP6V1G1,NOL12,ABHD2,TIMP2,KAT2A,SEPT9,KLF10,RDH10,WDR82,BCLAF1,MAP4K3,SEPT7,RAB22A,RHOB,ARF4,SRSF1,YIF1A,UTP20,TMEM168,GOLGA7,BRD2,DUSP3,GADD45B,MAPK6,H2AFX,RBMS1,AEN,NAA20,YY1 |
| 1.058e-05 | -11.46 | GSE360_HIGH_VS_LOW_DOSE_B_MALAYI_MAC_DN | MSigDB lists | GSE360_HIGH_VS_LOW_DOSE_B_MALAYI_MAC_DN | 191 | 52 | 17377 | 2626 |
TCF12,NCOR2,PRKCSH,TSC22D3,HEXB,LAGE3,MAN2B1,TMED3,PRKACA,ITGB5,RNF103,CNOT3,SLC25A36,TERF2IP,CRKL,FLAD1,PDCD10,AP3S2,ARF5,TANK,ARHGEF1,SEPT11,CYC1,CNPY3,TIPARP,BTG2,PRKDC,PPIE,ATXN1,PSMB9,H2AFV,TAZ,TARS,CYB5A,EPB41,RPA1,PI4K2A,DDX17,CDC16,BRD2,LTBP4,ACYP1,CSK,GOLGA8A,PSMD3,PPM1G,E2F1,DDX5,DUSP11,ATP6V1C1,PDCD4,DDX52 |
| 1.058e-05 | -11.46 | GSE14769_UNSTIM_VS_240MIN_LPS_BMDM_UP | MSigDB lists | GSE14769_UNSTIM_VS_240MIN_LPS_BMDM_UP | 191 | 52 | 17377 | 2626 |
BCL2L12,CTDP1,FGFR1OP,GCLM,RECQL,CKLF,UQCR10,RAC1,OLA1,TM9SF3,SLC29A1,SLC20A1,PITHD1,SPAG5,SEC11A,ERH,NAPG,INTS7,DNAAF2,AKAP8,XPA,PPCDC,BTF3L4,GEMIN6,FEM1B,GEMIN4,CPSF4,MRPL11,PSRC1,IDH3A,UTP15,TUFM,PSMA1,CDC6,PITPNB,TXNL4A,ANKRD46,ABHD5,SGSH,OSBPL11,MID1IP1,HNRNPR,TFDP1,PGRMC1,PRMT7,SAMD8,SSNA1,TATDN1,E2F2,ATMIN,RHEBL1,ZNF511 |
| 1.058e-05 | -11.46 | GSE23398_WT_VS_IL2_KO_CD4_TCELL_SCURFY_MOUSE_DN | MSigDB lists | GSE23398_WT_VS_IL2_KO_CD4_TCELL_SCURFY_MOUSE_DN | 191 | 52 | 17377 | 2626 |
COMMD10,NAT9,HECA,DNAJC5,MAX,UBN1,IVNS1ABP,WDYHV1,STARD7,DNAJC24,KLF13,TOP2B,COX4I1,RPAIN,CDC73,JMY,PAIP2,EEF2K,USF1,RAP1A,RP2,PDIA6,IFT46,HNRNPM,ANKRD37,FAM118B,EMB,ATP2C1,MTMR6,FRAT2,FXR1,RAB1A,ARL5B,RPS9,BSDC1,EIF3H,ARHGAP15,EIF3K,MAGED2,NSA2,HHEX,SURF4,UBXN2B,SNAP23,STK38,OAZ2,COX7A2L,PIAS2,ACADM,TMEM159,DYNC1LI2,PDCD4 |
| 1.058e-05 | -11.46 | GSE39110_DAY3_VS_DAY6_POST_IMMUNIZATION_CD8_TCELL_WITH_IL2_TREATMENT_UP | MSigDB lists | GSE39110_DAY3_VS_DAY6_POST_IMMUNIZATION_CD8_TCELL_WITH_IL2_TREATMENT_UP | 191 | 52 | 17377 | 2626 |
FGFR1OP,TXN,SUCLG1,SLC41A1,POC1A,DCTN2,TAP1,XIAP,TPX2,RRM1,TMX3,AGPAT3,TFRC,FBXO5,DTL,MLX,CCNA2,DUT,PRC1,ABCD1,TARDBP,AHCY,UBE3B,C12orf75,TACC3,PLK1,MND1,DDX28,TK1,TRAFD1,TIMP2,PGGT1B,RAD51AP1,LDHA,PSMG1,SSR2,CDC6,ANLN,SHCBP1,ARPC1A,KIF11,ASF1B,ISG15,RAD54B,OPTN,TRAM2,PML,C4orf46,ANP32E,FKBP5,ASNA1,EHD4 |
| 1.060e-05 | -11.45 | RAB8A (RAB8A, member RAS oncogene family) | protein interactions | 4218 | 88 | 31 | 17029 | 2761 |
GID8,RMND5A,NDUFA5,STAU1,MKLN1,RAB11B,RAB7A,RABIF,NDUFA7,RAB3IP,RAB1A,ARMC8,RAB5B,CDC73,TFRC,OPTN,RPA1,SDHB,CHCHD3,RPA2,RAP1A,MDM2,TBC1D17,MTMR4,ODF2,RRBP1,PQBP1,COX5A,POC5,RAB3IL1,DCTN1 |
| 1.063e-05 | -11.45 | CSTF2 (cleavage stimulation factor subunit 2) | protein interactions | 1478 | 76 | 28 | 17029 | 2761 |
CHMP2A,UBQLN4,IMMT,MAX,EWSR1,BABAM1,LSM8,BRCA1,PARN,SYMPK,APP,CDC73,ECH1,POLR2A,PAPOLA,SUB1,HGS,CHD3,MAP4,NUP153,SS18L1,RP2,CPSF4,TFG,PABPC1,DDB1,CDKN2A,CSTF1 |
| 1.063e-05 | -11.45 | RBL2 (RB transcriptional corepressor like 2) | protein interactions | 5934 | 76 | 28 | 17029 | 2761 |
AATF,FOXK1,CREG1,RAF1,MYBL2,CUL1,SMARCA4,CDC6,IRF3,BRCA1,LIN9,UBTF,PPP2CA,MDM2,CCNA2,BRD2,KMT5C,BIRC5,RBL1,E2F4,TFDP1,PML,E2F1,TFDP2,RBBP4,CDK2,E2F2,DCTN1 |
| 1.063e-05 | -11.45 | PSEN2 (presenilin 2) | protein interactions | 5664 | 76 | 28 | 17029 | 2761 |
CASP6,APH1A,EID1,METTL2A,CIB1,CSNK2A1,BCL2L1,DNAJB1,NOTCH2,CSNK1A1,PSEN1,APH1B,RAB11A,APP,NPLOC4,RHEB,CFLAR,CHKA,ERGIC3,CEP55,SRI,KIF22,ECD,PPP5C,TSPAN5,CAPN1,CSNK1D,PDCD4 |
| 1.063e-05 | -11.45 | SF3B6 (splicing factor 3b subunit 6) | protein interactions | 51639 | 76 | 28 | 17029 | 2761 |
SRSF11,SART1,COX15,CYLD,PRKDC,SUZ12,SF3B1,SF3B6,WDR18,ILF3,USP39,RPS24,THRAP3,SRSF5,VDAC1,SF3A2,APP,DHX15,CAND1,SF3B2,SAFB,RBMX,EFTUD2,ZNF326,SNRPG,FTSJ3,CDC5L,PRPF19 |
| 1.063e-05 | -11.45 | CCNE1 (cyclin E1) | protein interactions | 898 | 76 | 28 | 17029 | 2761 |
CCT2,RHOBTB3,KLF10,FOXM1,SF3B1,CDT1,CUL3,MYBL2,SMARCA4,CDC6,BRCA1,CDK5,UBTF,RB1,RRN3,PCNA,PSMA6,RBL1,E2F4,PIN1,UHRF2,PRC1,E2F1,CDKN1B,CDK2,COIL,CABLES1,ARID4A |
| 1.066e-05 | -11.45 | NONHISHMG17 | prints domains | PR00925 | 5 | 5 | 4652 | 473 |
HMGN3,HMGN1,HMGN5,HMGN4,HMGN2 |
| 1.067e-05 | -11.45 | cytoplasmic vesicle | cellular component | GO:0031410 | 2278 | 407 | 18223 | 2701 |
CCDC93,TMED7,RAB14,PDCD6IP,ADAM10,ZDHHC8,HEXB,TAP1,AP3M2,TGOLN2,NHLRC3,GYG1,SYNRG,CMTM6,KIFC1,PA2G4,PSMD1,DBNDD1,RABGAP1L,RAB4A,AP1M1,DNM2,AP2B1,MARCH2,KCNAB2,USO1,RHOBTB3,NRAS,ATG9A,AKT2,ARHGAP45,PPFIA3,SLC17A5,MCFD2,RAB22A,PLEKHF2,WAS,TMED10,RPS27A,AXIN1,PRDX5,ITGB1,VIPAS39,ATP6V0C,ARRB2,ANXA11,SVIP,PPIB,HSPH1,DNAJC5,GMFG,SCOC,GGA1,CCZ1,HLA-E,RHOC,RAB23,ACAP1,B4GALT1,MAN2B1,TMED3,ITGB5,APH1B,TMEM165,PSEN1,VPS25,COPG2,WDR48,COPB2,TMEM179B,GNS,CD59,SLC31A1,RPN1,ARPC5,SNX18,ZNRF2,ATP6V0A2,OSTF1,PIKFYVE,MVP,LPCAT1,SYTL3,TMED2,CYFIP1,FTL,PIGT,SIGMAR1,USP10,C1orf35,ADRB2,PKM,GOSR1,MAP2K2,CCT8,RHOB,PI4K2A,XRCC5,DERL1,MAGED2,CAT,SEC31A,SCARB2,OSBPL11,GOLGA2,ACLY,APPL2,ARAP1,GPI,CDK2,HEXA,SNX14,ALS2,EXOC3,RHOG,CYTIP,ANKRD27,ABCA3,GGNBP2,RAB11B,GPR89A,RAC1,VTI1A,OLA1,MON1B,NIT2,NIPA2,BCL2L1,AP1B1,PRKACA,STAM,CPNE3,APP,CD320,CRKL,RAB21,APLP2,SIAH1,MTMR4,TBC1D14,CLCN6,BRI3,CDKN1B,TAP2,TMEM9,TMBIM1,SNX8,ENPP4,CPNE1,CCT2,GOPC,VDAC2,ATP6V0A1,RAB1A,AP4E1,ALDH3B1,CHMP4A,DSN1,JAK1,DDOST,VPS26B,RAB24,WDR7,TICAM1,PDXK,TUBB,DYNC1LI2,ANKRD13D,ANXA6,MANBA,FLOT1,TRAK1,IFT27,RAB11A,HEATR5B,HLA-A,PIP5K1C,EBP,PSMD2,CLIC4,HUWE1,CNN2,ST8SIA2,TPCN1,SPTAN1,PDPK1,DENND1B,DENND4C,HEBP2,PACS1,KCNQ1,PICALM,SPPL2B,PRDX1,SH3GLB1,YIF1A,NUCB1,TMEM127,HGS,MAGT1,PRDX3,WNT5B,FAM3C,PML,PSAP,WDR91,YWHAH,VPS29,SNAPIN,MIB2,ADA2,COPA,SNX15,PTP4A3,SND1,AGFG1,UBQLN2,MAP1LC3B,RUFY1,BECN1,MAPK14,SEC16A,KCMF1,PCYOX1L,DST,RAB8A,RAP1A,CDC42,AP3S2,RAB35,SRI,ZFYVE27,RP2,CARMIL1,CYSTM1,EZR,ARHGDIB,RAB5B,OPTN,NECAP2,DPYSL3,CXXC4,TBC1D17,AGPAT2,GRIPAP1,CRCP,CAB39,ARRDC1,CLU,VPS4A,ROCK1,DVL1,CLN3,C2CD5,ATP6V0E1,CAPN1,NUMB,STARD3NL,UBE2D3,TBC1D12,TMUB1,AGTRAP,TM9SF4,NKD2,CDIP1,LAMTOR3,ASAH1,KLC1,RACGAP1,CDK13,RAB6A,RAPGEF6,RINL,AHCY,ATP6V0D1,KDELR1,VOPP1,ABHD2,CREG1,ARMC8,APPL1,RMC1,CAND1,NAP1L1,TMEM168,SNAP23,LAMTOR4,SIAH2,YWHAZ,CTSA,EHD4,ECPAS,UNC13C,NIPA1,WASF2,SNX27,CHMP2A,CORO7,TRAF7,GNPNAT1,DYNLL1,SLC2A1,COPE,ZFYVE21,RRAGC,ATP6V1B2,BCAP31,ATP6V0B,MDM2,WDR44,SAR1A,CORO1A,CYB5R1,APOOL,LMAN1,CLTB,PDIA6,F2R,GM2A,DVL2,EBAG9,CHP1,SNX25,CLCN3,UBQLN4,TIMP2,PPT1,RAB7A,PPIE,PSMB7,SLC26A6,WIPF1,BICD2,CHMP2B,TOLLIP,PEF1,ATP1A1,SURF4,VPS26C,TAB2,CLK3,SCAP,PSMD3,CANT1,AP1S1,ANP32E,CHMP4B,SCARB1,MAPK1,LTA4H,AP2S1,CHID1,ABCA1,TMEM33,MIF,SLC30A9,GOLIM4,PDAP1,SCYL1,SRGN,VPS45,TMX3,CHIC2,GGA2,AP3S1,SCYL2,MFSD10,TFRC,FZD6,SPPL2A,FERMT3,KIF5B,HERC3,FGFR3,CTSS,SLC1A4,SEC24C,ZDHHC13,ARHGEF2,YIF1B,CAMK2G,MYO5A,TGFB1,MLEC,RHOA,FAM49B,SNX2,RFFL,WDR81,NEU1,MAPK3,HSPA1B,CTSL,HLA-B,RAB18,SEC23IP,ATP6V1D,PDCD6,GOLGA7,SNAP29,PGRMC1,IMPDH1,PKD2,ATP6V1C1,RPS6KC1,CHMP7,PGAM1 |
| 1.068e-05 | -11.45 | GO_PRESPLICEOSOME | MSigDB lists | GO_PRESPLICEOSOME | 21 | 12 | 17377 | 2626 |
XAB2,LUC7L3,SF3B1,SNRPB,CRNKL1,SNRPG,SNRPD3,SNRNP70,PRPF39,LUC7L,SF3A2,LUC7L2 |
| 1.071e-05 | -11.44 | mitochondrial translational termination | biological process | GO:0070126 | 89 | 30 | 17256 | 2622 |
MRPL9,MRPL42,MRPS2,MRPS15,MRPL39,MRPL43,MRPL12,MRPS26,MRPS10,MRPL16,MRPS14,GFM2,MRPL19,MRPL50,MRPL2,DAP3,MRPL55,CHCHD1,MRPL27,MRPL34,MRPS27,MRPL54,MRPL48,MRPL40,MRPL21,MRPL11,MRPL13,MRPL3,MRPL32,MRPL57 |
| 1.073e-05 | -11.44 | XRN2 (5'-3' exoribonuclease 2) | protein interactions | 22803 | 80 | 29 | 17029 | 2761 |
EIF5A,CDKN2AIP,EIF3L,CUL3,MRPS10,DHX8,CUL1,CSNK2A1,NKRF,BRCA1,MCFD2,XPO7,MCM2,API5,TOLLIP,POLR2A,RPA1,CAND1,WWP2,RPA2,MAGED2,CDKN2AIPNL,KPNA1,TXLNA,TARDBP,UPF2,CRY2,TIPARP,CDC5L |
| 1.075e-05 | -11.44 | Nup214 (nucleoporin 214) | protein interactions | 227720 | 29 | 15 | 17029 | 2761 |
CYTH1,NUP188,NUP210,RAE1,HEXB,NUP107,OGT,NUP62,RANGAP1,NUP155,NUP153,SAFB2,NUP85,NUP205,SEH1L |
| 1.076e-05 | -11.44 | CBX5 (chromobox 5) | protein interactions | 23468 | 179 | 52 | 17029 | 2761 |
NOP9,MBD1,UNK,DNMT3A,SUZ12,MECP2,CHD1L,CDCA8,ENSA,SMARCA4,NSD3,ZNF518A,MAD2L2,MIS12,RB1,SUB1,SP100,SUV39H2,KMT5C,ZNF302,H2AFY,AHDC1,DNMT1,ARL5A,TIMM50,SRPK2,VHL,EHMT1,NARF,MKI67,NFATC2,AURKB,BRCA1,TRIM28,RPSA,CHAF1A,ZMYM3,CBX3,PPP2CA,KPNA4,PPP2R5A,DSN1,ZNF689,E2F4,E2F1,H2AFX,KPNA2,ZNF45,RBBP4,H3F3A,IFI16,ADNP2 |
| 1.079e-05 | -11.44 | GO_PROTEIN_COMPLEX_BINDING | MSigDB lists | GO_PROTEIN_COMPLEX_BINDING | 885 | 180 | 17377 | 2626 |
MAX,H2AFZ,ST13,ADD1,ADAM10,KIF2C,S1PR2,MAP1LC3B,GIT2,PRNP,KIFC1,DST,ABL2,RAP1A,PCNA,SYNM,DPYSL2,RCSD1,DNM2,NOC2L,AP2B1,KIF22,MAST2,SMARCE1,OGG1,PLK1,NRAS,RBX1,GMFB,KIF15,EZR,PSMG1,KRIT1,PAF1,RAD18,KIF18B,TMED10,MAP4,MYO18A,ITGB1,ADAM9,ACTB,ARRB2,PFKP,HDAC2,ANXA11,PPIB,MAPRE1,GMFG,CLSPN,DNAJB2,MUM1,STRN4,KIF23,NDUFA4,RACGAP1,NCKAP1,CDC73,CFLAR,FKBP1A,SMC3,ARPC5,MBD2,KIF13B,ZNF326,MSH2,CTR9,GNAI2,ATP6V0D1,HP1BP3,CYFIP1,MTA2,CAMSAP1,KRAS,ARID1A,ADRB2,ICAM2,ARPC1A,PI4K2A,HMGN2,AKAP1,FAS,PTPRF,GNAS,FNTA,GOLGA2,NSF,FAM83D,CABIN1,RBBP4,NDE1,CDK2,ZNF207,WASF2,ACTR3,PMS2,MYH9,SMARCA4,PRKACA,LYN,BCAP31,RPAIN,GNB2,SHC1,UCHL5,KIF14,CDKN1B,CORO1A,ABI1,RPRD1B,RNF169,PSRC1,TIMP2,MAPRE2,HMGN4,TUBGCP5,ELP4,WIPF1,NUSAP1,VDAC1,MBD3,PSMB9,TMEM201,KIF2A,SCAP,CORO1C,TULP3,NCOA1,PPP5C,H3F3A,REEP4,SMURF1,SMAD4,TUBB,ADAM23,USP13,KIF3B,ANXA6,RAE1,SRGN,HMGN3,MYO9B,RAB11A,TUBGCP2,NEIL2,HLA-A,FERMT3,JAKMIP1,PTPN2,KIF5B,STARD9,CTSS,PTEN,PRC1,PTPN11,ARHGEF2,H2AFY,NCOA2,MSH6,SPTAN1,PDPK1,TELO2,PPP1R9B,ADAM17,HMGN1,NASP,HMGN5,SNX2,WDR81,KIF11,MACF1,FADD,GNA12,KIF18A,LTBP4,BIRC5,LRPPRC,IGBP1,CD81,TERF1 |
| 1.084e-05 | -11.43 | SF3B4 (splicing factor 3b subunit 4) | protein interactions | 10262 | 113 | 37 | 17029 | 2761 |
RPS2,CYLD,EWSR1,CHERP,SUZ12,SF3B1,SRSF6,COPE,CUL1,UBE2I,PPP1R16B,RBM4,PAIP1,SF3B2,FKBP1A,EFTUD2,SS18L1,TERF2,CDC5L,STAU1,ZCCHC10,SF3B6,HNRNPF,CUL3,ILF3,UBE4B,SF3A2,ISG15,DDX17,CAND1,TIMM13,RBMX,SNRPG,FUS,RRS1,SMNDC1,DDX42 |
| 1.089e-05 | -11.43 | urinary_tract-bladder-carcinoma | COSMIC cancer mutations | urinary_tract-bladder-carcinoma | 14450 | 2224 | 17385 | 2587 |
HECA,ZBTB10,ABCC10,HEXB,TGOLN2,CCNL2,FBXO22,EEF2K,THAP4,RAD23B,ATP13A3,DNM2,FTSJ3,USP34,CCDC57,ERCC1,NRAS,EHMT1,KIF15,HNRNPF,WDHD1,MIER2,DIDO1,MCM2,RAB22A,SMAD2,MID1IP1,RPS27A,MYO18A,OGT,COX5A,SMAD1,ZNF75A,ANXA11,SLC25A33,GGA1,MUM1,CCZ1,TRIO,CUTA,RAB23,HAUS4,EIF2AK4,APH1B,PARN,CDC73,MYL6B,ATG4A,TMEM179B,PDXP,SMC3,GEMIN4,MVP,NUP85,PPP6R1,PABPC1,PPA1,IFRD1,AGGF1,FOXK1,RBM42,GTPBP4,MAP7D1,MRPL16,ELK1,EIF4H,RDH11,MAGED2,KPNA1,ETS2,TYW5,RUFY3,PDLIM5,ACSF2,EXOC3,RHOG,STARD7,C5orf30,INO80E,SLC35B2,RCOR3,LCLAT1,CPNE3,KIAA1147,ZNF420,AHCTF1,TBC1D22A,TBC1D14,GMEB1,NSFL1C,SEPT11,GPD1L,ZC3H3,ARL5A,PDCL3,SNX8,IDH3A,POLR2D,HTATIP2,MEF2D,TMEM147,TANC1,MAT2A,VPS26B,NSMCE2,CORO1C,CAMKMT,PPP5C,PITRM1,TUBB,ZNF445,SRSF6,HABP4,CCM2,FLOT1,BTN3A1,ATG2B,PPP1R3B,ZBTB45,HUWE1,ZNF260,ANXA5,LTN1,UBE3B,NAP1L4,ZNF710,ST8SIA2,RPL22L1,MED22,SPTAN1,STAU1,DDX24,TCTEX1D2,TACC1,MRS2,LDHA,RAB3IP,TTC33,PICALM,SH3BP5,SLC19A1,ACOX1,FAM3C,AEN,PARP10,YWHAH,THAP5,GPATCH4,FAM129A,TRIM11,YTHDC2,SNX15,RBM8A,NENF,SND1,RUFY1,TRIM65,ZER1,KRR1,RAB8A,NUP210,NT5DC1,NOC2L,TACC3,VPS13B,PTPN18,MIOS,SNRPB,CDC6,UTP3,PBRM1,ODC1,USP21,TRAM2,FBXO28,BCL7C,ARRDC1,ADAM9,DVL1,NUMB,ZNF564,FUBP1,CTU2,PARP12,ZCCHC9,CENPF,LAMTOR3,NCKAP1,RSAD1,TNS3,RINL,SSBP3,KIF13B,MBD2,XPA,AHCY,RBM3,GLE1,LRSAM1,NTPCR,NSDHL,CAMSAP1,ZNF761,METTL22,ICAM2,APPL1,BBS12,ANKRD46,RXRB,SDHB,PCM1,GALNT2,TMEM168,NLRC5,RUVBL2,BTBD10,MYO9A,CCNB2,USP7,GLT8D1,RPLP2,SUCLG1,ARID2,TMX4,SLC2A1,PCBP1,LYN,BCAP31,VAV1,TMEM69,MRPL50,PSMA6,ZNF473,ZNF302,BRPF3,TARDBP,BCAP29,PRPF19,KDM3B,MND1,CLCN3,BIRC3,RAB7A,ANKRD33B,PPIE,CHMP2B,VDAC1,EIF3H,TMEM201,IDE,DHX16,UHRF2,XRCC3,PARD3,BCL2L12,MCM10,PDAP1,CDCA8,TMX3,GTF3A,ARF1,SLC12A9,TUBGCP2,DNAJB9,HOMER1,POLR1B,RNF5,RBM15B,PPAN,RHOA,RPRD1A,BTAF1,TOP3A,ARHGEF12,PCGF1,DDX23,RAB18,CACNB1,TRIM26,PDCD6,ATP6V1D,L3MBTL3,FAM110A,NEIL3,BBX,IMPDH1,TAF12,NR2F2,PGAM1,HIPK3,IFI16,NUP188,PNISR,PRKCSH,USP39,UBE2I,PARK7,SLC25A37,ASPHD2,ZNF428,RAB4A,TRA2B,SUCLG2,CISD2,TAF5L,SMARCE1,ZNF800,CDC5L,ZNF524,SGCE,OSBP2,NSUN2,USP22,EIF3A,ZMYM3,DOT1L,IWS1,ANKRD10,WAS,KIF18B,TPP2,ZMAT3,B4GALT2,PRPF38B,RECQL,C9orf78,EWSR1,GADD45G,RRM1,ACAP1,B4GALT1,CYCS,SUPT7L,TMEM165,NPLOC4,CNOT3,WDR48,RTKN,CEP104,EXOSC7,KLHL5,LRRC8D,PPP4R1,MSH2,PIGG,OSTF1,FBXL7,MRPL40,TNRC18,SYTL3,FAM171A1,APOL1,EIF5A,GCC2,PRIM2,RDH10,MFNG,GORASP2,CAPZA2,ADRB2,CCT8,MTR,PHF6,PFDN5,SLCO4A1,TTC13,GOLGA2,RBMX,MED15,PIAS2,APPL2,CDKN2A,ZNF511,ATXN3,RAF1,KIAA0232,C2orf49,EPM2A,CCNA2,MTMR4,BRI3,TP53BP2,AQR,RBM12B,ILKAP,CDK12,SAP30,BRD4,NARF,LRRC8A,ELP4,ABHD11,PKMYT1,ASB13,TRIM28,SUPT16H,EIF3K,CHMP4A,ATF6,XRCC4,ADAM23,PRPF4B,NDUFS1,DEPDC1,MECP2,SECISBP2,HMG20A,WWP2,JAKMIP1,SLC25A36,CCNK,AXIN2,CITED2,JMJD4,ANKRD37,KAT2A,RABIF,ADSL,PACS1,BMS1,KCNQ1,OTUD3,ARSK,MACF1,KIF11,COMMD4,KLF6,SMAP2,FADD,SH3GLB1,MYO1F,CBX3,INF2,PPP1R11,DUSP11,DDX5,WDR62,TAF6,ESPL1,PURA,DDB1,DEF6,IPO4,FAM83G,UBL3,NAT9,PIGM,UBE2Q1,PTP4A3,BRIX1,MRPL19,ZNF696,SF3B2,PCYOX1L,CDC42,SYNM,GOT2,JAZF1,HADHB,RPF2,SLC35C2,CNNM3,CARM1,SRPK2,WDR41,LARS,CCDC138,LRBA,TMEM216,SUMF2,KMT2C,OGFR,PRPSAP1,ASF1B,RPL37,MAN2A2,EIF4ENIF1,NIP7,U2SURP,MIA2,VPS4A,ATP6V0E1,PPP1R2,XPNPEP3,RGS2,LYAR,FAM89B,POLR2I,TRAFD1,SUGP2,GBA,SYVN1,DAPK3,ARHGAP15,MASTL,UAP1,NFIL3,FN3KRP,YWHAZ,CTSA,TOB1,ADNP2,TCF12,PRKAB1,MDH2,SMARCA4,ORC1,RRN3,UBXN2A,IARS,CD3EAP,KIF14,EXOSC1,CS,CLTB,DNAL4,POU2AF1,UBQLN4,SELPLG,ATXN1,GLO1,OGDH,BICD2,CADM1,EDEM2,HERPUD2,TOLLIP,FANCE,MBD3,PDHX,RPS9,ARNTL,ANP32E,FKBP5,TMEM101,CCDC125,ABCA1,PDCD2L,GCLM,RAE1,DCTN2,NUP54,CHIC2,PAWR,MXD4,DCUN1D4,PIP4K2A,XPR1,FERMT3,KIF5B,KLHL20,SEC24C,RRBP1,ARHGEF2,ANP32A,LDLRAD3,STAT3,MYO5A,NIPAL3,AMPD2,TXNL1,PHF20L1,DCAF6,FAM49B,TMEM39A,ATP2C1,RFFL,COG1,RCOR1,PRMT2,TFEB,LEMD2,SERF1B,UPF1,ELMO1,ZC3H7B,DTX4,ZMIZ1,TERF1,HRAS,CCDC93,FGFR1OP,TMED7,PIGQ,AGPAT1,CNTROB,PPP1R16B,GSDMB,TTC9C,PDS5B,NUP153,SENP1,PGAP2,TMEM115,PLEKHM3,PLEKHF2,BRMS1,PWWP2B,TRIM47,WDR11,AXIN1,SMG9,LONP2,CERK,SLC4A2,EZH1,ITGB5,LMNA,MCTS1,DDX56,EIF2S2,SLC38A5,FOXN2,CARS2,PRRC2A,C16orf72,RB1CC1,ZMYND11,PGS1,MYBL2,UHRF1BP1,SRSF5,MPG,MATR3,CYB5A,SETD3,TEX30,PTAR1,CNOT6,NDE1,EGLN1,ZNF207,ANKRD27,ABCA3,SARNP,IVNS1ABP,RMI2,MON1B,TMEM97,NIT2,NUF2,ZNF267,KTN1,APP,PRKD3,CLUAP1,ATP2A2,UTP18,GRSF1,DUT,ZCCHC2,ANAPC7,RNF19A,FAM76B,CLN6,GCC1,RNF169,ADCY7,ATP6V1G1,ENPP4,RNPS1,CDCA2,FKBP3,GPR137,DDX17,CHCHD3,PEX5,CDC16,HIPK2,MBOAT1,TICAM1,PDXK,ZBTB11,ANXA6,TMBIM4,GMCL1,UBE4A,IL21R,ETS1,ZNF92,CAPN2,ADD3,SUV39H2,TTLL12,TPCN1,TMX1,LYPLA2,HNRNPM,MFSD12,LDHB,PPP3CA,NUDT8,POLK,MTMR12,ZP3,PDE3B,KIF18A,CCDC6,WNT5B,MAPK6,LY75,SLC25A19,RGL1,PSAP,WDR76,IGBP1,FAF1,COX15,THOC1,AGRN,PPP1R15B,CSNK2A1,EBNA1BP2,GIT2,BIRC2,ATPAF1,DLG5,ABL2,XRCC2,ZFYVE27,MCMBP,PTPRK,CDC37,METTL1,SP3,HARS,GMFB,ESYT1,ANLN,RAB5B,RHEB,DPYSL3,TBC1D17,TIMM13,CDCA4,TONSL,NRM,NAGLU,ACTB,ZNF45,TMUB1,CTCF,ASAH1,DOCK11,CRLF3,ASXL2,LRRC14,NUS1,SLC27A4,AFF1,MDFIC,MAML1,CYTH1,NQO2,UTP15,EIF2AK1,EIF4G2,ZDHHC3,MOSPD3,ITPRIPL1,CDC27,SNAP23,TBPL1,PRMT7,KCTD7,NDUFA5,UGP2,DYNLL1,COPE,HCFC1R1,ZADH2,GGPS1,RPAIN,RAD23A,ATP6V0B,PDK2,STRBP,MRPL34,PDCD2,SAP30L,CLPTM1,RPL35,BTG2,DNAJC9,MTMR6,NFATC2,KDM1B,ARL5B,USP36,ATP1A1,CLK3,PSMD3,MAFK,CEP55,DNAJC17,ZNF436,NCOA1,SLC25A39,ZC3HC1,ZNF146,ATXN7L2,CDC40,GOLIM4,SMAP1,GNE,SMC6,ARFIP2,NKRF,CHAC2,BZW2,WRNIP1,SS18L1,CAMK2G,MLEC,ZNF202,PPWD1,FAM50B,RHOT2,TPD52L2,GOLGA7,TWSG1,GLG1,PGRMC1,FAM126A,RPS6KC1,UBE2C,PPCS,NDUFB6,TMEM41B,PLXNA1,CCNB1,SLC20A1,COMMD6,ASAP2,SNUPN,CNPY4,TFG,PLCL2,SEH1L,ATG9A,PBK,MKI67,DDX20,AMDHD2,GALNT7,SLC17A5,CCNF,FOXRED1,RBM47,WDR4,DHTKD1,TRAF5,HDAC2,PWWP2A,HSPH1,MAPRE1,CHTF18,KIF23,SLC35B1,NOTCH2,PMF1,JMY,FKBP1A,SNX18,ATIC,CTPS1,ATP6V0A2,PIKFYVE,RNF135,LPCAT1,EEF1D,TMED2,FTL,PHF10,DDX28,ZNF84,SIGMAR1,PIP4K2C,RIT1,PLEC,KDM3A,FAS,EPRS,ZNF777,TMEM54,QARS,PPP3R1,TCOF1,CABLES1,NRBP1,DNMT3A,RWDD1,CKLF,TRIP10,SF3B1,CAST,SUZ12,RPS6KA1,RAC1,GPR89A,OLA1,GNB2,FLAD1,APLP2,KDM2A,CDKN1B,TNPO2,TALDO1,ATP13A1,RFC3,MAPRE2,ERF,CUL3,SLBP,KIAA1586,H2AFV,GAR1,PSMB9,POLG2,DHX57,NSA2,HSPA4,JAK1,GOLGA8A,TBL3,SEL1L,H2AFX,KLHDC4,PDCD11,ATMIN,POLQ,OTUD5,NCOR2,ANKRD13D,PKP4,SCAMP3,BABAM1,CDCA3,SLC25A12,BLM,TMCC3,GTF2F1,CRAT,AHSA1,PRC1,UPF2,COPS7B,SLC38A10,CNOT6L,CNPY3,UBE2M,IFT46,TSHZ1,ZFP64,STRIP1,DENND4C,DENND1B,ILF3,LRRC1,RHOT1,TSR2,MARK2,PRDX1,PLD3,NUCB1,FBXO21,GNA12,C1orf131,PRDX3,PFDN4,HNRNPH3,TFDP1,STX18,KHSRP,ASNA1,VPS29,S100PBP,MIB2,IER2,NOP2,UBN1,DCAF15,NF1,ALKBH5,MOGS,TAF6L,BECN1,MAPK14,SNAPC4,RNF103,BCAT2,MBD4,METTL14,ZNHIT6,IMPAD1,RCSD1,PHTF1,KIF22,ZBTB22,OGG1,TRIM14,COPS8,FYTTD1,TRIM8,RRM2,SOX4,ABHD5,UBTF,CXXC4,PAF1,UEVLD,SPATA2,PQBP1,IARS2,ATXN2L,RPS15,PIGN,AGTRAP,CIB1,XPO7,SRRT,ZNF449,CAPZA1,GLTP,KIFAP3,BCL2,N4BP2,HP1BP3,THNSL1,CAND1,GNAS,TSC1,RBM25,CDCA5,ZFP90,RBBP4,ZBTB24,SMARCD1,MBD1,WASF2,MMACHC,TOMM20,GNPNAT1,MPHOSPH8,HNRNPUL2,CHD1,C2orf68,CCDC50,AKAP8,PARL,RPN2,CHTOP,F2R,FAM3A,TMEM14C,SCYL3,ABI1,HTRA2,MOSPD1,RLIM,FAM172A,ZNF500,NLN,WIPF1,BOLA1,BUD13,NDUFB1,PEF1,EIF3G,BTBD1,TAB2,CHCHD1,TULP3,WDR59,CANT1,SCARB1,GAS2,USP11,SMURF1,PPP2R2D,TSPAN5,CDS2,MAGEH1,EYA1,CDK2AP2,LETMD1,KLF13,RGS1,HDDC2,MAN1A1,FBXO5,GART,TANK,PELO,BRD7,MRPL11,SAMD4B,WDR81,MEN1,ZNF407,MFN2,COX8A,ZRANB2,MBD6,SRSF3,IDH3B,TATDN1,ATP6V1C1,TSC2,LACTB2,RBM4,ZNF275,ANKRD39,RPL23A,CDKN2C,NAPG,USF1,DNAAF2,MECR,AP1M1,UPRT,CRY2,ECD,MOB1A,RNF26,TIPARP,LRRC59,BAK1,ZNF559,RHOBTB3,GABPA,WBP1,NUTF2,ARF4,KRIT1,BOLA3,AHNAK,RAD18,RNASEL,CHPF2,PDCD4,NXT2,HIVEP3,KIAA0100,CLSPN,RHOC,DHX9,PDCD7,PSMD9,COPB2,TFAP4,CD59,RNFT1,MEGF8,RIMS3,EFTUD2,FBXO7,CPSF4,MRPL21,PHKG2,LUC7L2,SRSF11,EIF3L,MTA2,TYW1,USP10,ITM2A,SSR2,BCLAF1,MTX1,SFXN5,FNTA,TXNDC16,ZNF830,TMEM159,MRPL3,ALS2,TRIM41,KARS,POC1A,ANK3,PTTG1,TPX2,TBC1D13,DAZAP2,GLRX3,STMN1,C19orf48,REPS1,ABHD16A,FBXL6,SH3BP1,MTA1,UBA5,CLCN6,INTS12,RPRD1B,CGGBP1,CPNE1,FAM118B,GOPC,E2F3,CIRBP,CRNKL1,PFKFB3,GORAB,RAB1A,GIGYF1,PPP2CA,KIF2A,CCDC14,LSM6,RNF38,SNRPG,DMWD,USP13,ZFP91,TRMT6,IP6K2,SLC25A43,IFT27,PMVK,NEIL2,RRP36,SRXN1,RPA2,PSMD2,CLIC4,PDCD10,CBWD2,COQ4,ITGB8,ARF5,ARHGEF1,GTF2H2,FBXL19,TTPAL,UTP20,MAGT1,GPS2,DBI,SSNA1,MRFAP1L1,CD81,TMEM131,WDR13,FANCI,PAPOLA,CREM,FANCL,TET3,GLIS2,IL6ST,INTS1,ASB6,PLK1,RPP25,SEPT9,CELSR2,RBX1,APH1A,RAD51AP1,PSMG1,UBE2V1,EAF2,KRTCAP2,LUC7L,LSG1,NECAP2,TRIM4,AGPAT2,CHD3,E2F4,PRPF4,KPNA2,BEND6,CLN3,DNAJC30,FAM208A,NGLY1,POT1,RMND5A,HJURP,PHB2,DNAJB2,FAM53C,NKD2,KLC1,CDK13,ADCK5,COX4I1,DNAJB1,RAB6A,ARID1B,C1GALT1,MLX,CCP110,ZNF746,CTR9,NIPSNAP1,ABHD2,DCAF8,ACSL3,LDB1,MAP4K3,ARMC8,NMT2,IRF5,RPL36,HAUS8,MBIP,ORMDL2,COX7A2L,ZDHHC7,SIL1,FAM122A,UNC13C,BCCIP,SART1,TRAF7,TOR1AIP1,LAGE3,TM9SF3,ZNF121,OIP5,NRF1,WDR44,PPME1,PIN1,EFCAB11,RPAP1,CABLES2,LMAN1,AHCYL1,TOP1MT,STRAP,SPSB3,ZNF583,SNX25,ARHGAP17,ZNF780B,NUP155,DCLRE1C,MRPS14,RHBDF2,SUGP1,RBL1,FASTK,UBXN2B,STK38,AP1S1,SLC22A23,H3F3A,SMAD4,RAD51D,SLC30A9,CMAS,UNK,NADSYN1,HMGN3,NCAPG,SCYL2,FZD6,HERC3,GTPBP3,CTSS,ORC3,RNLS,YTHDC1,ACP2,HMGN5,CSRP1,METTL5,ABCF2,TUFM,RANGAP1,HAGH,API5,ZFR,SEC23IP,E2F1,USP20,RBPJ,PDCD6IP,MAX,LUZP1,GXYLT1,ADAM10,CXXC1,TSC22D3,AP3M2,CUL1,NANS,MYEF2,ANKRD26,PA2G4,NOL11,FIZ1,ZNF200,MARCH2,SLC26A2,SRP72,KLF10,LACTB,CBFB,RFC2,RAB2B,MAP3K4,HHEX,MAP4,MRPL27,BTF3,PTPDC1,NMD3,PTOV1,COX5B,DNAJC5,DHPS,ANKH,VAV2,PRKAA1,C16orf87,GSPT2,TATDN3,DLGAP4,PXMP2,PSEN1,ZNF79,PDXDC1,VPS25,NDUFS7,YY1AP1,FAM192A,RPN1,LHX8,ARPC5,TPST1,DAPK1,PIK3IP1,CYC1,SOCS5,PIGT,EMB,WDR1,ZNF574,C1orf35,EXOSC9,ARID1A,FXR1,GOSR1,MAP2K2,TWISTNB,AKAP1,XRCC5,HMGN2,PI4K2A,CAT,DERL1,MTHFD2,HSPBP1,ARAP1,USP32,FAM83D,CABIN1,SMPD4,GPI,CYTIP,TP53RK,REPS2,RAB11B,UROD,SLC39A13,BCL2L1,NUDT19,DECR1,RALB,SIAH1,ADCY9,LPIN2,SOCS6,TTC3,ANKLE2,OAF,VDAC2,EDF1,ERC1,ANKZF1,RAD51C,ZNF282,DSN1,HINT1,DGCR8,SAFB,HAGHL,RWDD4,FTSJ1,NCLN,BEND3,EYA2,DYNC1LI2,MANBA,SLC41A1,FAM76A,TKT,CBLL1,ARGLU1,POFUT1,FAM8A1,HEATR5B,HLA-A,EBP,RFWD3,FJX1,FUT8,BTF3L4,PTPN11,MRPL54,FEM1B,CNN2,MTX2,MSH6,PDLIM2,LONRF3,RFXANK,FBXO9,GUF1,RPL32,ZHX1,OAZ2,WDR91,HIGD2A,GPR89B,RORB,POLA2,ZNF76,MTX3,COPA,PHRF1,DST,RAB35,SIVA1,GPATCH1,TCEA1,DRAM2,TRAPPC13,SNRNP200,LAP3,NCK1,VHL,SREK1,ARHGDIB,PITPNB,HSPB11,BRWD1,PPM1G,SH3GLB2,BAZ1B,ACBD4,CAB39,STK11,CLU,CHEK2,TSTD2,MRPL13,CHPT1,DCAF5,CAPN1,UBE2D3,PPP1R12A,ZCCHC8,GORASP1,NACA,C19orf25,RPL15,PCSK7,EPN1,THRAP3,QSOX2,TTF1,NUP205,PRPF18,CHKA,DTL,MED10,ZRANB1,MCPH1,SLC12A2,ATP6V0D1,CSNK1G3,NUDT4,RPL6,VKORC1,SLTM,EVC2,KLHL15,SIAH2,SLC16A1,EHD4,SNRNP70,C11orf1,APOL2,N4BP2L2,SNX27,CHMP2A,CORO7,FEZ2,PMS2,UCK2,CLCC1,EXT2,MXD1,USP5,HNRNPA2B1,SAP130,NVL,PPP6C,CYB5R1,ZNF770,EBAG9,RNF25,PCGF6,METTL2A,PON2,HNRNPR,STAT6,HPS5,MAPK1,BRD9,TMEM33,DNAJC2,TRIP12,SHPRH,SCYL1,MYO9B,GFM2,SPPL2A,FASTKD3,FGFR3,PPIG,TMEM99,H2AFY,NDUFS8,ATG13,ERI3,FBL,FRMD8,SLC35A1,MICAL3,ELOVL5,TIMMDC1,HELB,PSPC1,MIER1,SCFD2,NDRG3,CDK11A,MTMR3,MEGF9,ACAT1,CENPT,PLOD3,RAB3IL1,RAB14,ADD1,KDM4A,MRPS15,XIAP,DHX8,GLUD1,PABPC4,CDK5,CALM2,PSMD1,NEK6,NSRP1,RABGAP1L,SRSF4,KCNAB2,PCBP2,MLST8,PLK3,ZNF672,MRPL43,HSDL1,TOPORS,MCL1,PPFIA3,SMC2,ICMT,SLC50A1,STOML2,LIMK1,ZNF689,PRDX5,ATE1,MLYCD,FBXL3,TFDP2,E2F2,PFKP,DDX42,SSRP1,MRPL9,MRPS2,STRN4,TOP2B,ZNRF3,DDRGK1,RAVER2,GNS,INTS7,INPP5A,MCM5,PHF14,NAGPA,TIMM8B,ETV3,DHX29,TEX10,MAN1B1,CBFA2T2,ABCF1,RHOB,LRRC14B,DTWD1,PTPRF,SCARB2,OSBPL11,CCDC86,DUSP3,MDH1,HEXA,RNF139,SNX14,ZNF296,TRERF1,UBR2,CHD1L,ACTR3,WDTC1,MYH9,CREBL2,NIPA2,PRKACA,SAFB2,ANKIB1,STAM,ARL6IP6,RAB21,SP100,ZKSCAN1,DDA1,NUP107,ANKRD13C,MAVS,CEP63,ATF2,RBM15,DCTN1,SHOC2,PSRC1,MAP4K4,ATP6V0A1,NUSAP1,NDUFA7,DNAJA1,TAZ,TAF2,C19orf54,RPLP1,WDR7,CBLN2,FUS,GEN1,LRP8,COIL,LRCH1,GALK1,ZNF786,RPS2,SESTD1,TRAK1,JMJD6,SIKE1,AKT1S1,KRI1,FBXO3,ERH,GATC,NDUFB4,PPP1R8,PRDM4,GTSE1,GEMIN6,DCP1A,SGCB,S100A6,IMPA2,NUDC,PDPK1,TK1,TNFAIP3,GALC,ZNF512,KIAA0930,MRPS10,DDX39A,RPA1,ZNF862,ZNF180,KEAP1,POLE,TATDN2,PITX1,CAPN7,LRPPRC,PML,HMGB2,USF2,ANAPC4,SRM,DDX47,MCCC1,S1PR2,SEC16A,SSR1,LIN9,PCNA,ZNF639,ETV6,PIK3R2,PPCDC,TXLNA,MYBL1,CCAR1,MRPL32,ABCC5,BAZ2A,PBXIP1,TLK1,MRPL12,EZR,LNX2,LRP5,BRCA1,PRKRA,STX16,EPB41,OPTN,SEPT1,SOCS4,QRSL1,OSGEPL1,GLCCI1,NUDT11,GEMIN7,LZTR1,RACGAP1,PPP3CB,B4GALT4,RLF,RAPGEF6,RB1,VMP1,PPIL2,MEA1,TIMELESS,AHDC1,ALDH18A1,TMEM8A,PREB,ABCC1,TRAPPC9,AACS,MEMO1,KRAS,RTF1,UBE4B,NFATC2IP,ARPC1A,ZNF174,PSMC4,GOLGA4,PALB2,PRPS2,NIPA1,TIGD2,RNF114,FOXM1,MRPL39,XAB2,SUMO2,DUSP22,COMMD8,RPL11,CSDE1,MDM2,CORO1A,MINPP1,POC5,DVL2,PSMA8,TIGD5,SLC26A6,CYP20A1,PRPF3,RPSA,SRSF1,DNAJC10,SCAP,ZNF700,PLEKHG4B,TIMM17A,FAU,LTA4H,AP2S1,USP53,INTS2,CTDP1,MIF4GD,CDT1,ARID5A,SUMF1,GGA2,CSNK1A1,RMI1,TFRC,PTPN2,IRF4,STARD9,NDUFV1,SLC1A4,CWC27,SLC35B4,DDX31,ABCD1,RPAP3,CNTN5,SNX2,ZMYM5,CCDC34,CHCHD6,BSDC1,CDKN2AIPNL,FBXO41,KPNA4,BIRC5,TFE3,SNAP29,CDCA7L,PKD2,CHMP7,SAT2,ZNF496,TAP1,NHLRC3,IKBIP,EIF1B,KIFC1,DBNDD1,CYB5RL,PARPBP,CDC25B,DNMT1,NOL12,ORAI2,USO1,AKT2,NOL8,GNG7,AURKB,MCFD2,SLC25A5,ZFAND5,MAK16,STT3A,EIF2D,ITGB1,PTPN7,UQCRH,RRS1,ARRB2,RTN3,ZNF598,DDX58,WSB2,PPIB,MUT,HLA-E,MAN2B1,METTL3,CFLAR,RNF121,MEX3C,KLF16,HDAC7,DAD1,BDH1,PCYT2,GNAI2,ANKHD1,TERF2,MORC3,KCTD20,SEPT8,DCTD,PKM,TOMM40,PATL1,ADSS,SERTAD2,ZFP92,NSF,DCK,ACLY,VCPIP1,PPP6R2,PPP6R3,MAP3K5,YY1,CDK2,RNF14,ZC3HAV1,SYS1,ZBTB37,URB2,MAGED1,KLHL18,SLC25A44,AP1B1,SDHA,PAIP2,PHC2,CRKL,MOAP1,TERF2IP,CYHR1,ZNF75D,SHC1,UCHL5,NAA35,CDKN2AIP,CCT2,MKLN1,HMGN4,GALK2,CDC23,SHCBP1,AP4E1,PRDM11,VEZF1,PPP2R5A,ACYP1,STAT1,PPA2,TRIM32,RHEBL1,R3HCC1L,TCF3,MRI1,BRAP,AGPAT3,MYNN,SPR,RAB11A,REEP5,FOXO3,MAD2L2,CCDC28A,PIP5K1C,RBM17,MAT2B,PTEN,CENPJ,NCOA2,PACS2,SMC4,NEK7,NET1,PARP4,TBRG4,ANAPC2,YIF1A,SGSH,HGS,TTLL4,MFAP1,CCDC69,BRWD3,ESYT2,SKA3,NPHP4,UBE2E2,HNRNPAB,PLXNC1,ST13,DNAJC24,ZNF107,KIF2C,SLC29A1,AGFG1,SIRT2,USP48,UBQLN2,FKBP2,CUTC,EDC3,ZNF804A,RAP1A,THADA,EIF4A3,AP3S2,ATG3,DPYSL2,PPP1R12C,AKR1B1,JOSD1,NDUFB9,RP2,TECR,ARID4A,TIMM50,TDP1,DPM1,FOPNL,SLC16A7,SLC25A22,WDR82,STK17B,CHAF1A,GEMIN5,COPS6,PSMC1,SLC12A7,TM9SF4,ZNF768,MED13L,TIA1,MEF2A,EPHX2,RHBDD1,NFATC3,BUD31,ZNF335,KNTC1,UBE3C,ACAD8,ZNF189,ALDH9A1,KDELR1,TSTA3,CIC,OXR1,TMEM241,NAP1L1,ODF2,EXOC4,NUP62,PITPNA,KIAA1328,NAA20,PTDSS1,MZT2B,PDSS2,C7orf26,TMEM106C,IMMT,ASH1L,CHERP,WDYHV1,PLAGL2,CHKB,TWF2,PAIP1,ANKRD28,FARSA,ANKLE1,SAR1A,SCAMP4,APOOL,PDIA6,ACSL5,AZI2,RAD54B,DAP3,ZNF317,AKNA,REEP4,CBX4,MIF,KIF3B,GOLPH3L,SH2D3A,CASP6,TOR3A,SRGN,DBF4,MFSD10,SAC3D1,CTNNBL1,YIF1B,CLDND1,TTC17,SLC25A1,GINS1,CSNK1G2,TELO2,HMGN1,ADAM17,NASP,ASPM,PPP1R21,PRKAR1B,SYMPK,TARS,MAPK3,HSPA1B,HLA-B,PLAA,ATAD2,ZNF330,OSBPL8,KBTBD7,PREPL |
| 1.101e-05 | -11.42 | SCHLOSSER_MYC_TARGETS_AND_SERUM_RESPONSE_DN | MSigDB lists | SCHLOSSER_MYC_TARGETS_AND_SERUM_RESPONSE_DN | 45 | 19 | 17377 | 2626 |
AMD1,LDHA,CUL1,EBNA1BP2,ODC1,MRPL19,AKAP1,PRNP,PA2G4,EXOSC7,SYNCRIP,UTP18,TIMM17A,TFDP1,FTSJ1,FBL,RRS1,BYSL,TRIM14 |
| 1.104e-05 | -11.41 | RNA Polymerase II Transcription | REACTOME pathways | R-HSA-73857 | 159 | 48 | 10287 | 1696 |
CTDP1,CDC40,SARNP,THOC1,POLR2K,SRSF6,RBM8A,SNRPD3,CDC73,PAPOLA,GTF2F1,CCNK,ZNF473,EIF4A3,SRSF4,CTR9,TCEA1,CPSF4,CHTOP,GTF2H2,CSTF1,FYTTD1,SRSF11,POLR2I,POLR2G,POLR2L,SNRPB,ELOA,POLR2D,RNPS1,SLBP,RTF1,EAF2,SRSF5,DDX39A,SYMPK,POLR2A,SRSF1,IWS1,SUPT16H,TAF2,PAF1,POLR2J,TAF12,SRSF3,SNRPG,TAF6,SSRP1 |
| 1.109e-05 | -11.41 | DNA-templated transcription, elongation | biological process | GO:0006354 | 111 | 35 | 17256 | 2622 |
CTDP1,POLR2I,POLR2G,POLR2L,POLR2K,ELL2,ELOA,POLR2D,ELP4,RTF1,CDK13,PBRM1,EAF2,CDC73,POLR2A,TWISTNB,GTF2F1,SUPT16H,IWS1,TAF2,PAF1,CCNK,UBTF,POLR2J,CD3EAP,CTR9,TAF12,POLR1B,TCEA1,ZNRD1,GTF2H2,TAF6,CDK12,SSRP1,ELOF1 |
| 1.110e-05 | -11.41 | nuclear replication fork | cellular component | GO:0043596 | 42 | 18 | 18223 | 2701 |
POLA2,MCM10,PRIM2,HELB,WDHD1,GINS4,PRIM1,RPA1,RPA2,PCNA,TONSL,XPA,BAZ1B,TIMELESS,TOP1MT,PURA,CDC5L,PRPF19 |
| 1.115e-05 | -11.40 | GSE11864_UNTREATED_VS_CSF1_PAM3CYS_IN_MAC_UP | MSigDB lists | GSE11864_UNTREATED_VS_CSF1_PAM3CYS_IN_MAC_UP | 172 | 48 | 17377 | 2626 |
CCNC,GMFG,PPP1R2,PHB2,MDH2,MAGED1,ALKBH5,PCSK7,USP39,TGOLN2,CDK13,CRLF3,FKBP1A,DECR1,RAP1A,CCP110,AP3S2,JAZF1,AFF1,FAM76B,GNAI2,SAMD4B,ABHD2,PSRC1,LONRF3,TSPYL4,NET1,VHL,GNG7,BCLAF1,RTF1,MEF2D,NFATC2IP,SEPT7,EDEM2,TAZ,SLC25A5,SLTM,NSA2,SCARB2,BRD2,RAB24,LPCAT4,RBMS1,SRSF3,REEP4,ARRB2,CWC25 |
| 1.115e-05 | -11.40 | GSE21546_WT_VS_ELK1_KO_ANTI_CD3_STIM_DP_THYMOCYTES_DN | MSigDB lists | GSE21546_WT_VS_ELK1_KO_ANTI_CD3_STIM_DP_THYMOCYTES_DN | 172 | 48 | 17377 | 2626 |
MRPL9,CHERP,MRPS2,WDYHV1,TOR3A,TMEM109,RRM1,CDCA8,PXMP2,EBNA1BP2,SLC29A1,BLM,TCF19,RMI1,SPAG5,SNRNP25,NRF1,CTNNBL1,NSRP1,PPIG,ATIC,POP7,UBE3C,NUP85,PPIF,PSRC1,TMEM115,LLPH,GLO1,FAM133B,AURKB,BRCA1,MCM2,BUD13,AP4E1,FANCE,GAR1,CLNS1A,DDX23,CDCA4,KIF18B,NRM,PRPF4,NR2F2,CABLES1,CCDC59,GPATCH4,POLQ |
| 1.116e-05 | -11.40 | RNA 3'-end processing | biological process | GO:0031123 | 120 | 37 | 17256 | 2622 |
INTS2,CDC40,SARNP,THOC1,SRSF6,RBM8A,CDC73,APP,TUT4,PAPOLA,ZNF473,EXOSC7,INTS7,EIF4A3,GRSF1,INTS1,SRSF4,CHTOP,CPSF4,AHCYL1,FBL,ZC3H3,PABPC1,CSTF1,SRSF11,EXOSC6,POLR2D,RNPS1,SLBP,EXOSC9,SRSF5,DDX39A,SYMPK,RPSA,SRSF1,PAF1,SRSF3 |
| 1.117e-05 | -11.40 | MARTINEZ_RB1_AND_TP53_TARGETS_UP | MSigDB lists | MARTINEZ_RB1_AND_TP53_TARGETS_UP | 570 | 124 | 17377 | 2626 |
TMEM106C,ZBED3,TCF12,IMMT,HNRNPAB,ADD1,PTTG1,TMEM109,UCK1,NIT2,CCNL2,DUSP22,GIT2,BCAP31,PAPOLA,USF1,PRKD3,ATP2A2,SAR1A,IL6ST,DNM2,AP2B1,INTS12,TCEA1,MARCH2,LMAN1,MOB1A,ATF2,ASB6,ARL5A,CTDSP2,DRAM2,ABCC5,USP34,MAPRE2,PBK,PFKFB3,GLO1,PITPNB,BICD2,SOX4,SERP1,RAB2B,EIF3A,CLNS1A,DPYSL3,IDE,JAK1,ACYP1,TPP2,LMBR1,RBMS1,ST3GAL2,ACTB,CHEK2,DVL1,CHPT1,UBE2D3,RECQL,ZNF445,SCOC,CASP6,DAP,SRGN,RRM1,MEF2A,RACGAP1,LANCL1,DNAJB1,EPHX2,VPS25,TUBGCP2,PIP4K2A,TFRC,WDR48,SPAG5,NDUFS4,FERMT3,ADD3,C4orf3,ZNF260,CTR9,ACAD8,NSUN4,IFT46,MORC3,PDPK1,PPP3CA,SIGMAR1,ABCF2,AMD1,PRKAR1B,ILF3,SEPT8,ITM2A,KRAS,MTX1,KIF11,EIF4H,SPPL2B,ZFR,PRDX1,RPA1,PTPRF,CAT,GNAS,PFDN5,GNA12,NAP1L1,PCM1,FNTA,NSF,TWSG1,ZNF330,ACOX1,CTBS,ASNA1,PSAP,RBBP4,RNF14,PDLIM5,HIPK3,MRPL3,RNF114 |
| 1.122e-05 | -11.40 | positive regulation of nucleic acid-templated transcription | biological process | GO:1903508 | 1451 | 278 | 17256 | 2622 |
ZNF496,H2AFZ,CXXC1,HEXB,CCNL2,EDRF1,PARK7,GLMP,USF1,NOL11,DNM2,ECD,SENP1,CDC5L,KLF10,AATF,GABPA,TOPORS,USP22,CBFB,ARF4,DOT1L,HHEX,SMAD2,RPS27A,AXIN1,OGT,RNASEL,TFDP2,SMAD1,E2F2,HDAC2,DDX58,HIVEP3,HSPH1,PRKAA1,DHX9,EZH1,PSMD9,PSEN1,CDC73,DDRGK1,TFAP4,FOXN2,MYDGF,NUP85,FOXK1,MTA2,MYBL2,BCLAF1,EXOSC9,ARID1A,ADRB2,ELK1,KDM3A,MAP2K2,SERTAD2,ETS2,SETD3,RBMX,PIAS2,PPP3R1,CEBPG,YY1,MAP3K5,RNF14,CDK2,EGLN1,RHOG,KARS,TRERF1,IVNS1ABP,RPS6KA1,RAF1,MAGED1,CREBL2,APP,CCNA2,SHC1,SP100,GMEB1,LPIN2,MAVS,ATF2,RBM15,CDK12,RPRD1B,PSRC1,BRD4,KAT7,WBP2,E2F3,EDF1,MEF2D,TRIM28,SUPT16H,DDX17,TAF2,VEZF1,SAFB,HIPK2,STAT1,ATF6,ATMIN,POU3F2,MECP2,TCF3,ABHD14B,WDR5,BLM,ETS1,FOXO3,MAD2L2,WWP2,GTF2F1,CCNK,PRDM4,CARF,CITED2,CREB1,NCOA2,PPP3CA,KAT2A,ILF3,RFXANK,ZP3,KLF6,PICALM,FADD,GPS2,PITX1,TFDP1,PML,HMGB2,DDX5,CD81,USF2,YWHAH,RORB,CCNC,ZBED3,ZNF76,IER2,HNRNPAB,AGRN,THOC1,KMT2E,GPBP1L1,AAMDC,SIRT2,MAPK14,CREM,TET3,GLIS2,ZNF639,ETV6,PIK3R2,MYBL1,ARID4A,CARM1,ELOF1,RYBP,SP3,DEAF1,NCK1,VHL,MRPL12,UBE2V1,LRP5,BRCA1,EAF2,SOX4,USP21,UBTF,PAF1,E2F4,ZNF268,CHEK2,DVL1,PSMC1,ZNF564,PPP1R12A,CHCHD2,CTCF,MEF2A,CDK13,PPP3CB,THRAP3,RLF,CRLF3,ASXL2,ARID1B,RB1,SUB1,NFATC3,MLX,MED10,SSBP3,ZNF746,CTR9,ICE2,YBX1,MDFIC,MAML1,ERLIN1,LDB1,UTP15,RTF1,NFATC2IP,EIF2A,IRF5,RXRB,CAND1,PSMC4,TBPL1,NLRC5,NUP62,ZFP90,RUVBL2,SMARCD1,TCF12,ASH1L,FOXM1,PLAGL2,SMARCA4,IRF3,PCBP1,NRF1,RRN3,PIN1,TARDBP,F2R,DVL2,MOSPD1,POU2AF1,NFATC2,RBL1,SCAP,STAT6,ARNTL,NCOA1,AKNA,MAPK1,SMAD4,NAT14,SLC30A9,BCL2L12,DNAJC2,EYA1,AGO2,KLF13,HMGN3,NKRF,PAGR1,IRF4,BRD7,ARHGEF2,SS18L1,STAT3,TGFB1,HMGN1,DCAF6,HMGN5,PRKDC,PRMT2,MEN1,TFEB,MAPK3,ATAD2,TFE3,E2F1,KMT2B,PKD2,RBPJ,ZMIZ1,NR2F2,HRAS,IFI16 |
| 1.122e-05 | -11.40 | positive regulation of transcription, DNA-templated | biological process | GO:0045893 | 1451 | 278 | 17256 | 2622 |
ZNF496,H2AFZ,CXXC1,HEXB,CCNL2,EDRF1,PARK7,GLMP,USF1,NOL11,DNM2,ECD,SENP1,CDC5L,KLF10,AATF,GABPA,TOPORS,USP22,CBFB,ARF4,DOT1L,HHEX,SMAD2,RPS27A,AXIN1,OGT,RNASEL,TFDP2,SMAD1,E2F2,HDAC2,DDX58,HIVEP3,HSPH1,PRKAA1,DHX9,EZH1,PSMD9,PSEN1,CDC73,DDRGK1,TFAP4,FOXN2,MYDGF,NUP85,FOXK1,MTA2,MYBL2,BCLAF1,EXOSC9,ARID1A,ADRB2,ELK1,KDM3A,MAP2K2,SERTAD2,ETS2,SETD3,RBMX,PIAS2,PPP3R1,CEBPG,YY1,MAP3K5,RNF14,CDK2,EGLN1,RHOG,KARS,TRERF1,IVNS1ABP,RPS6KA1,RAF1,MAGED1,CREBL2,APP,CCNA2,SHC1,SP100,GMEB1,LPIN2,MAVS,RBM15,ATF2,CDK12,RPRD1B,PSRC1,BRD4,KAT7,WBP2,E2F3,EDF1,MEF2D,TRIM28,SUPT16H,DDX17,TAF2,VEZF1,SAFB,HIPK2,STAT1,ATF6,ATMIN,POU3F2,MECP2,TCF3,ABHD14B,WDR5,BLM,ETS1,FOXO3,MAD2L2,WWP2,GTF2F1,CCNK,PRDM4,CARF,CITED2,CREB1,NCOA2,PPP3CA,KAT2A,ILF3,RFXANK,ZP3,KLF6,PICALM,FADD,GPS2,PITX1,TFDP1,PML,HMGB2,DDX5,CD81,USF2,YWHAH,RORB,CCNC,ZBED3,ZNF76,IER2,HNRNPAB,THOC1,AGRN,KMT2E,GPBP1L1,AAMDC,SIRT2,MAPK14,CREM,TET3,GLIS2,ZNF639,ETV6,PIK3R2,MYBL1,ARID4A,CARM1,ELOF1,RYBP,SP3,DEAF1,NCK1,VHL,MRPL12,UBE2V1,LRP5,BRCA1,EAF2,SOX4,USP21,UBTF,PAF1,E2F4,ZNF268,CHEK2,DVL1,PSMC1,ZNF564,PPP1R12A,CHCHD2,CTCF,MEF2A,CDK13,PPP3CB,THRAP3,RLF,CRLF3,ASXL2,ARID1B,RB1,SUB1,NFATC3,MLX,MED10,SSBP3,ZNF746,CTR9,ICE2,YBX1,MDFIC,MAML1,ERLIN1,LDB1,UTP15,RTF1,NFATC2IP,EIF2A,IRF5,RXRB,CAND1,PSMC4,TBPL1,NLRC5,NUP62,ZFP90,RUVBL2,SMARCD1,TCF12,ASH1L,FOXM1,PLAGL2,SMARCA4,IRF3,PCBP1,NRF1,RRN3,PIN1,TARDBP,F2R,DVL2,MOSPD1,POU2AF1,NFATC2,RBL1,SCAP,STAT6,ARNTL,NCOA1,AKNA,MAPK1,SMAD4,NAT14,SLC30A9,BCL2L12,DNAJC2,EYA1,AGO2,KLF13,HMGN3,NKRF,PAGR1,IRF4,BRD7,ARHGEF2,SS18L1,STAT3,TGFB1,HMGN1,DCAF6,HMGN5,PRKDC,PRMT2,MEN1,TFEB,MAPK3,ATAD2,TFE3,E2F1,KMT2B,PKD2,RBPJ,ZMIZ1,NR2F2,HRAS,IFI16 |
| 1.127e-05 | -11.39 | identical protein binding | molecular function | GO:0042802 | 1670 | 318 | 17224 | 2647 |
FGFR1OP,PDCD6IP,MAX,TSC2,ADD1,ADAM10,HEXB,XIAP,TAP1,DHX8,GLUD1,OAT,PARK7,USF1,THAP4,TRA2B,NUP153,CISD2,TFG,BAK1,TMEM115,LACTB,MCL1,NUTF2,HHEX,MID1IP1,SMAD2,WAS,RAD18,AXIN1,TPP2,MLYCD,SMG9,SMAD1,TRAF5,ARRB2,DDX58,EWSR1,MAPRE1,MUT,DHPS,RRM1,KCTD17,VPS25,TFAP4,SLC31A1,PDXP,ATIC,CTPS1,MSH2,DAPK1,TPST1,TNPO3,RNF135,MVP,TERF2,FTL,GCC2,CPQ,PIP4K2C,UHRF1BP1,DCTD,ADRB2,PKM,FXR1,MATR3,FAS,CAT,EPRS,CSK,DCK,RBMX,TYW5,CEBPG,MAP3K5,NDE1,NRBP1,ALS2,TRIM41,KARS,DNMT3A,NQO1,TRIP10,RAF1,MAGED1,SLC39A13,MYH9,BCL2L1,DAZAP2,SAFB2,GLRX3,APP,PHC2,CRKL,APLP2,SP100,SIAH1,TBC1D22A,BRI3,TP53BP2,GPD1L,CLN6,RPRD1B,CGGBP1,GPX4,SNX8,CPNE1,MAPRE2,MKLN1,DRAP1,CUL3,LRRC8A,MEF2D,POLG2,MAT2A,CHMP4A,DGCR8,STAT1,ATF6,FUS,TRIM32,PDXK,PPP5C,XRCC4,COIL,POU3F2,ANXA6,MRI1,TCF3,TKT,BRAP,CBLL1,JMJD6,GMCL1,BLM,ETS1,HMG20A,PDCD10,PTEN,CENPJ,DCP1A,CREB1,TPCN1,IMPA2,S100A6,MSH6,LDHB,TK1,TNFAIP3,LDHA,ZP3,DDX39A,SPPL2B,PRDX1,FADD,CIP2A,SH3GLB1,CBX3,KEAP1,PRDX3,PML,NAXE,SSNA1,MRFAP1L1,PSAP,USF2,YWHAH,SSSCA1,ESYT2,SRM,ADA2,ST13,CSNK2A1,ABCB10,BECN1,EDC3,PRNP,PCNA,CDC42,GOT2,DPYSL2,ZNHIT6,IL6ST,PPCDC,CARM1,FGFR1OP2,PLK1,SNRNP200,TRIM8,HARS,RIOX2,EZR,ESYT1,PRKRA,ODC1,PRPSAP1,LUC7L,OPTN,CHAF1A,SEPT1,SH3GLB2,ARRDC1,ACTB,CHEK2,DVL1,NAA60,STARD3NL,HJURP,CENPF,SDC2,EPHX2,CRLF3,CHKA,SUB1,RB1,MLX,BANF1,XPA,ARL6IP1,ORAI1,TIMELESS,TENM3,AHCY,GLTP,BCL2,GLE1,ALDH18A1,MCPH1,ATP5IF1,TSTA3,NQO2,LDB1,EIF2AK1,SEPT7,APPL1,ZNF174,IRF5,DAPK3,PAXX,MBIP,PCM1,UAP1,PRPS2,NFIL3,SLC16A1,DNPH1,YWHAZ,RUVBL2,TCF12,MMACHC,UGP2,GNPNAT1,DYNLL1,SLC2A1,IRF3,GGPS1,EXT2,MIEF1,OIP5,NRF1,PDK2,MDM2,TARDBP,CORO1A,AHCYL1,DVL2,HTRA2,PRPF19,UBQLN4,CLCN3,CPOX,ATXN1,PRPF3,CADM1,VDAC1,PON2,IDE,CLK3,STAT6,CANT1,CHMP4B,SCARB1,MAPK1,SMAD4,PARD3,MIF,MCM10,CASP6,DCTN2,ARFIP2,SUMF1,MYO9B,TFRC,SPPL2A,WRNIP1,KIF5B,FGFR3,ABCD1,STAT3,RNF5,MYO5A,CAMK2G,TGFB1,SNX2,NADK2,PRMT2,SNRPA,TARS,MAPK3,CNOT9,PDCD6,BIRC5,ACAT1,PKD2,ACADM,NR2F2,SAT2,TERF1 |
| 1.131e-05 | -11.39 | regulation of proteasomal protein catabolic process | biological process | GO:0061136 | 176 | 49 | 17256 | 2622 |
USP7,ATXN3,SUMO2,UBXN1,NKD2,SIRT2,UBQLN2,CSNK1A1,PRKACA,PSEN1,BCAP31,ANKIB1,PARK7,FBXO22,DDRGK1,USP5,RAD23A,RPL11,MDM2,UCHL5,DDA1,RAD23B,RNF19A,SENP1,SOCS5,RYBP,PLK1,PLK3,UBQLN4,LONRF3,RBX1,PBK,GBA,EDEM2,PSMC4,HSPA1B,GNA12,KEAP1,HSPBP1,SOCS4,OGT,CLU,DVL1,RNF14,PSMC1,CSNK1D,USP13,SVIP,RNF114 |
| 1.136e-05 | -11.39 | GO_PML_BODY | MSigDB lists | GO_PML_BODY | 94 | 31 | 17377 | 2626 |
SP3,USP7,MAX,TRIM8,UBN1,SUMO2,TOP3A,SMC6,TOPORS,BLM,UBE2I,PATL1,RPAIN,PARK7,DAPK3,RPA1,RFWD3,RPA2,RB1,EIF4ENIF1,SP100,KLHL20,PTEN,NSMCE2,HIPK2,ARNTL,PML,PIAS2,CHEK2,HIPK3,MORC3 |
| 1.142e-05 | -11.38 | VDAC3 (voltage dependent anion channel 3) | protein interactions | 7419 | 109 | 36 | 17029 | 2761 |
COX15,IMMT,SARNP,PHB2,TKT,LAMTOR3,COX4I1,ATP5F1B,FAM8A1,BCAP31,NDUFS4,SSR1,RPN1,NDUFS8,CISD2,CYC1,TECR,ATF2,ATP6V0D1,TMX1,ABCC1,PPIF,DDX24,VDAC2,NDUFA7,TOMM40,VDAC1,SDHB,SUGP1,ATP1A1,MAGT1,DDOST,PQBP1,COX5A,ATP5F1A,HRAS |
| 1.144e-05 | -11.38 | EIF3G (eukaryotic translation initiation factor 3 subunit G) | protein interactions | 8666 | 57 | 23 | 17029 | 2761 |
EIF3L,TK1,CYLD,EIF3D,GADD45G,CUL3,KRAS,BRCA1,EIF1B,EIF3G,APP,PAIP1,EIF3H,EIF3A,LMNA,EPB41,EIF3K,GOLGA2,AHSA1,PIN1,EIF5,CD81,POT1 |
| 1.144e-05 | -11.38 | TRIP10 (thyroid hormone receptor interactor 10) | protein interactions | 9322 | 57 | 23 | 17029 | 2761 |
CYFIP1,ARHGAP17,COPA,TRIP10,COPE,AP1B1,PRKACA,LYN,COPB2,NPLOC4,ABL2,OSBPL11,WAS,CDC42,WDR44,SH3BP1,DNM2,UPF2,STAT3,SMARCE1,SMURF1,TERF1,POT1 |
| 1.144e-05 | -11.38 | V$E2F1_Q6_01 | MSigDB lists | V$E2F1_Q6_01 | 221 | 58 | 17377 | 2626 |
POLA2,REPS2,CLSPN,RAB11B,TRMT6,SMC6,CTCF,ORC1,ASXL2,STMN1,CNOT3,FBXO5,TFAP4,PCNA,INTS7,CD3EAP,PPP1R8,FIZ1,MSH2,PCYT2,MRPL40,MCMBP,ANKHD1,DNMT1,SLC25A1,CDC5L,ZNF524,NASP,ERF,RB1CC1,PRKDC,AMD1,ILF3,E2F3,DNAJC9,SREK1,PKMYT1,MCM2,SRSF1,DDX17,HMGN2,EIF3K,ATAD2,SYNCRIP,RBL1,HNRNPR,ZNF367,GADD45B,KBTBD7,E2F1,AP1S1,ATE1,FKBP5,SASS6,GEN1,TSTD2,ESPL1,FAF1 |
| 1.146e-05 | -11.38 | positive regulation of proteasomal ubiquitin-dependent protein catabolic process | biological process | GO:0032436 | 85 | 29 | 17256 | 2622 |
PLK1,PLK3,LONRF3,RBX1,SUMO2,NKD2,GBA,SIRT2,UBQLN2,CSNK1A1,PSEN1,BCAP31,ANKIB1,FBXO22,HSPA1B,DDRGK1,USP5,RAD23A,KEAP1,MDM2,HSPBP1,SOCS4,CLU,DVL1,RNF19A,RNF14,CSNK1D,SOCS5,RNF114 |
| 1.152e-05 | -11.37 | GSE12392_IFNAR_KO_VS_IFNB_KO_CD8_NEG_SPLEEN_DC_UP | MSigDB lists | GSE12392_IFNAR_KO_VS_IFNB_KO_CD8_NEG_SPLEEN_DC_UP | 177 | 49 | 17377 | 2626 |
CYTIP,ZBTB10,EWSR1,IVNS1ABP,B4GALT5,TSC22D3,AGFG1,ZNF267,MAP1LC3B,RAPGEF6,CDC73,RGS1,DNAJB9,CFLAR,CHKA,ANKRD28,CEP104,RRN3,CDC42,GLIS2,TANK,CLDND1,RP2,TAGLN2,MCMBP,DNMT1,FRMD8,PPIF,EIF5A,CYTH1,ETV3,BIRC3,NCK1,ELL2,NEK7,ARL5B,KDM3A,GOSR1,SERTAD2,KPNA4,BRWD1,UAP1,CLK3,CORO1C,MAFK,EHD4,NDE1,ZMIZ1,TOB1 |
| 1.152e-05 | -11.37 | GSE17322_CD103_POS_VS_CD11B_HIGH_LUNG_DC_UP | MSigDB lists | GSE17322_CD103_POS_VS_CD11B_HIGH_LUNG_DC_UP | 177 | 49 | 17377 | 2626 |
PWWP2A,TXN,UFC1,SLC39A13,ZFYVE21,SDF2L1,ZNF267,SLC35B2,IKBIP,DAZAP2,RGS2,AP3S1,REEP5,CMTM6,PIP4K2A,SSR1,CALM2,RPN1,GLIS2,RIMS3,SOCS6,DAPK1,CYB5R1,ZNF710,PDIA6,PDLIM2,RYBP,SNX8,PGAP2,RBX1,RAB7A,RAD51AP1,MTMR12,PLEC,PRMT2,MPG,RFC2,KDM3A,ZMYM3,AHNAK,MAGT1,TMED10,BCL7C,DHTKD1,SPCS3,RBPJ,PPP6R2,YWHAH,ZBTB24 |
| 1.159e-05 | -11.37 | AK1 (adenylate kinase 1) | protein interactions | 203 | 26 | 14 | 17029 | 2761 |
KDM3B,GEMIN5,TERF2IP,DECR1,BRD4,OGT,TIA1,SUCLG2,BUD13,KMT2C,SLC12A2,TERF1,UTP4,APP |
| 1.159e-05 | -11.37 | SNCG (synuclein gamma) | protein interactions | 6623 | 26 | 14 | 17029 | 2761 |
TERF2IP,TIMP2,DYNLL1,TUFM,ILF3,ADRB2,AHCYL1,MAPK1,EXT2,TERF1,POT1,SSSCA1,MAPK3,FUBP1 |
| 1.161e-05 | -11.36 | MORF_BMI1 | MSigDB lists | MORF_BMI1 | 77 | 27 | 17377 | 2626 |
HMGN4,PRKCSH,PRKDC,PPIE,XPO7,AP3S1,TAZ,SERP1,MFSD10,POLR2A,GTF2F1,RPA2,CDKN2C,RPN1,DNAJC8,CSK,TXLNA,CS,ATXN2L,CAPZA1,TNPO3,TCEA1,TCOF1,B4GALT3,PTDSS1,NUDT3,SMNDC1 |
| 1.172e-05 | -11.35 | GO_PHOSPHORYLATION | MSigDB lists | GO_PHOSPHORYLATION | 1182 | 231 | 17377 | 2626 |
CCNC,COX15,FGFR1OP,NDUFB6,ADAM10,NF1,UQCR10,HMGXB3,SNX15,CUL1,CSNK2A1,CCNB1,MAPK14,RBM4,EEF2K,CDK5,CALM2,ABL2,PSMD1,NEK6,IMPAD1,PIK3R2,NDUFB9,FNIP2,MAST2,CDC25B,FGFR1OP2,CDC37,SRPK2,PLK3,PLK1,NRAS,RBX1,AKT2,PBK,TLK1,GMFB,AURKB,IL12RB1,PRKRA,STK17B,MAP3K4,MKNK1,SMAD2,RPS27A,PSMD8,LIMK1,AXIN1,BAZ1B,CAB39,DHTKD1,COX5A,UQCRH,STK11,CHEK2,RNASEL,ROCK1,SMAD1,PSMC1,PFKP,SEPHS2,COX5B,NDUFV2,GMFG,CLSPN,PRKAA1,TRIO,LAMTOR3,CERK,MEF2A,NDUFA4,ADCK5,CDK13,COX4I1,CYCS,PPP3CB,EIF2AK4,PSMD9,NDUFS7,NDUFS4,CHKA,PPP4R1,DAPK1,MSH2,BCL2,MDFIC,CYC1,ALDH18A1,PIKFYVE,MAML1,PHKG2,N4BP2,CSNK1G3,MORC3,MAPKAPK3,RB1CC1,PIP4K2C,PSMA1,KRAS,MAP4K3,EIF2AK1,EIF2A,MAP2K2,PSMB3,DAPK3,PSMC4,PI4K2A,MASTL,CSK,DCK,CSNK1G1,PRPS2,COX7A2L,FN3KRP,GPI,MAP3K5,CDK2,NRBP1,PRKAB1,NDUFA5,TP53RK,RAF1,RPS6KA1,UCK2,UCK1,CHKB,ADPGK,PRKACA,LYN,CPNE3,APP,CRKL,VAV1,PRKD3,PDK2,PSMA6,SHC1,F2R,CDK12,SCYL3,ABI1,ULK3,PSMA8,MAP4K4,TAOK1,CUL3,PSMB7,PFKFB3,GALK2,NDUFA7,PKMYT1,OGDH,NDUFB1,TAZ,TOLLIP,PSMB9,ERC1,TRIM28,JAK1,CLK3,TAB2,HIPK2,PSMD3,FASTK,STK38,NDUFA11,PDXK,PPP5C,MAPK1,CSNK1D,PRPF4B,GALK1,NDUFS1,SH2D3A,MECP2,SCYL1,CCM2,GNE,BRAP,IP6K2,CDK11B,CSNK1A1,PMVK,PIP4K2A,SCYL2,PIP5K1C,FASTKD3,CCNK,FGFR3,PSMD2,NDUFV1,NDUFA2,NDUFB4,PTPN11,NDUFS8,MAP3K14,CREB1,NDUFA3,STAT3,GTF2H2,IMPA2,CAMK2G,SPTAN1,PDPK1,TGFB1,CSNK1G2,TK1,GUK1,NEK7,PRKDC,PRKAR1B,LDHA,ILF3,TBRG4,MEN1,CDK11A,MARK2,MAPK3,NEK1,BIRC5,GPS2,MAPK6,KBTBD7,PML,COX8A,FAM126A,NDUFS5,PGAM1,RPS6KC1,HRAS,HIPK3 |
| 1.185e-05 | -11.34 | cytoplasmic vesicle part | cellular component | GO:0044433 | 1469 | 275 | 18223 | 2701 |
TMED7,RAB14,ADAM10,ZDHHC8,HEXB,TAP1,AP3M2,TGOLN2,NHLRC3,GYG1,SYNRG,CMTM6,PA2G4,PSMD1,DBNDD1,RAB4A,AP1M1,DNM2,AP2B1,MARCH2,KCNAB2,USO1,NRAS,ATG9A,ARHGAP45,SLC17A5,MCFD2,RAB22A,PLEKHF2,TMED10,RPS27A,ATP6V0C,SVIP,HSPH1,DNAJC5,GMFG,GGA1,CCZ1,HLA-E,RAB23,ACAP1,B4GALT1,MAN2B1,TMED3,TMEM165,PSEN1,VPS25,COPG2,COPB2,TMEM179B,GNS,CD59,ARPC5,SNX18,ZNRF2,ATP6V0A2,OSTF1,PIKFYVE,MVP,LPCAT1,TMED2,CYFIP1,FTL,C1orf35,ADRB2,PKM,CCT8,RHOB,PI4K2A,XRCC5,MAGED2,SEC31A,CAT,SCARB2,OSBPL11,ACLY,APPL2,GPI,SNX14,EXOC3,RHOG,ANKRD27,ABCA3,RAB11B,GPR89A,RAC1,VTI1A,OLA1,MON1B,NIT2,BCL2L1,AP1B1,STAM,CPNE3,APP,CD320,APLP2,RAB21,MTMR4,CLCN6,BRI3,TAP2,TMEM9,TMBIM1,SNX8,CPNE1,ENPP4,CCT2,GOPC,ATP6V0A1,RAB1A,AP4E1,ALDH3B1,CHMP4A,DSN1,DDOST,RAB24,TICAM1,PDXK,TUBB,ANXA6,MANBA,RAB11A,HLA-A,PIP5K1C,PSMD2,CLIC4,HUWE1,CNN2,TPCN1,SPTAN1,DENND4C,HEBP2,KCNQ1,PICALM,SPPL2B,HGS,MAGT1,WNT5B,FAM3C,PML,PSAP,WDR91,YWHAH,VPS29,SNAPIN,ADA2,COPA,SNX15,RUFY1,BECN1,MAPK14,SEC16A,KCMF1,PCYOX1L,RAB8A,RAP1A,AP3S2,RAB35,SRI,ZFYVE27,CYSTM1,RAB5B,OPTN,NECAP2,AGPAT2,GRIPAP1,CAB39,VPS4A,ROCK1,CLU,C2CD5,ATP6V0E1,CAPN1,STARD3NL,UBE2D3,AGTRAP,LAMTOR3,CDIP1,ASAH1,CDK13,RAB6A,ATP6V0D1,KDELR1,VOPP1,CREG1,ARMC8,APPL1,RMC1,CAND1,SNAP23,LAMTOR4,CTSA,YWHAZ,EHD4,UNC13C,CHMP2A,SNX27,GNPNAT1,DYNLL1,COPE,RRAGC,ZFYVE21,ATP6V0B,MDM2,SAR1A,WDR44,CYB5R1,CORO1A,CLTB,LMAN1,APOOL,GM2A,SNX25,CLCN3,TIMP2,RAB7A,PPIE,PSMB7,SLC26A6,CHMP2B,TOLLIP,PEF1,SURF4,TAB2,SCAP,PSMD3,AP1S1,CANT1,CHMP4B,SCARB1,MAPK1,LTA4H,AP2S1,MIF,GOLIM4,PDAP1,SRGN,SCYL1,VPS45,TMX3,GGA2,AP3S1,SCYL2,MFSD10,FZD6,TFRC,SPPL2A,FERMT3,CTSS,SEC24C,ZDHHC13,CAMK2G,TGFB1,RHOA,MLEC,FAM49B,SNX2,RFFL,WDR81,NEU1,HSPA1B,CTSL,HLA-B,RAB18,ATP6V1D,PDCD6,SEC23IP,GOLGA7,SNAP29,PGRMC1,IMPDH1,PKD2,CHMP7,PGAM1 |
| 1.185e-05 | -11.34 | GSE23308_CTRL_VS_CORTICOSTERONE_TREATED_MACROPHAGE_MINERALCORTICOID_REC_KO_DN | MSigDB lists | GSE23308_CTRL_VS_CORTICOSTERONE_TREATED_MACROPHAGE_MINERALCORTICOID_REC_KO_DN | 182 | 50 | 17377 | 2626 |
COX15,IMMT,FAM208B,TMEM184B,ST13,IVNS1ABP,DHPS,XIAP,RAB23,B4GALT1,CUL1,AGPAT3,HMGN3,HAUS4,SLC29A1,CHAC2,ZADH2,RGS1,LIN9,HOMER1,RCSD1,PRC1,SGCB,ABCC1,VOPP1,ENPP4,CYTH1,PPT1,NOA1,METTL5,PSMB7,SLC16A7,MTMR6,CYB5A,GLOD4,SH3BP5,HLA-B,SYNCRIP,PARG,MPV17,SIAH2,HMGB2,NAA20,RUFY3,FBXL3,PDLIM5,NGLY1,TSTD2,PDCD4,PFKP |
| 1.185e-05 | -11.34 | GSE5589_UNSTIM_VS_180MIN_LPS_STIM_MACROPHAGE_DN | MSigDB lists | GSE5589_UNSTIM_VS_180MIN_LPS_STIM_MACROPHAGE_DN | 182 | 50 | 17377 | 2626 |
POLA2,PTMS,CYLD,PPP1R12A,XAB2,ABHD14B,IRF3,SNRPD3,NCAPG,RAPGEF6,CNOT3,RPL23A,SUB1,ATG3,ZDHHC13,MSH2,NFU1,ORC3,ARL5A,IMPA2,PDCL3,NUDC,SEC61B,ACP2,ASPM,PPP1R21,TLK1,HSDL1,SLBP,CDC6,ARHGDIB,AZI2,CYFIP2,PRPSAP1,PSMB9,ARHGAP15,NEU1,CBX3,SGSH,POLE,CCDC86,SNAP23,PRPS2,NRM,HAGHL,CENPT,AKNA,FAU,CLN3,RNF139 |
| 1.185e-05 | -11.34 | GSE29164_CD8_TCELL_VS_CD8_TCELL_AND_IL12_TREATED_MELANOMA_DAY7_UP | MSigDB lists | GSE29164_CD8_TCELL_VS_CD8_TCELL_AND_IL12_TREATED_MELANOMA_DAY7_UP | 182 | 50 | 17377 | 2626 |
KIF3B,ASH1L,ZCCHC8,FAM207A,GNPDA1,RAF1,GSPT2,ZFYVE21,ABHD14B,AGFG1,SLC25A44,FAM8A1,APP,HMG20A,HEATR5B,C2orf68,KRR1,TMEM69,SOCS6,CNPY4,GPATCH1,SEPT11,ATG13,CTDSP2,MED22,TERF2,AMPD2,CYFIP1,GALC,TACC1,NEK7,ZNF202,TUBGCP5,SREK1,EMP3,PLEKHM3,PRPSAP1,MFAP1,APPL2,RWDD4,PKD2,FAM126A,PLOD3,ZSWIM3,BRWD3,TAF6,HIPK3,MRPL3,ANXA11,ZBTB24 |
| 1.185e-05 | -11.34 | GSE1460_DP_VS_CD4_THYMOCYTE_UP | MSigDB lists | GSE1460_DP_VS_CD4_THYMOCYTE_UP | 182 | 50 | 17377 | 2626 |
GLT8D1,TXN,MCM10,CDK2AP2,UCK2,DHX8,SLC29A1,STMN1,PSMD9,SAP130,CDKN2C,NAPG,RAB8A,NDUFV1,CTNNBL1,FBXO7,DAPK1,MCPH1,IFT46,PCBP2,SPSB3,CGGBP1,NUDC,VOPP1,ORAI2,HEMK1,TIMP2,AATF,BAZ2A,TEX10,PSMB7,LRRC1,EAF2,RHOT2,PEF1,MAP2K2,PAF1,RAD51C,PEX5,UPF1,ACYP1,NEIL3,PPM1G,DHTKD1,PRMT7,SRSF3,SNRNP70,BRD9,PPP2R2D,FAF1 |
| 1.185e-05 | -11.34 | GSE22589_HEALTHY_VS_SIV_INFECTED_DC_UP | MSigDB lists | GSE22589_HEALTHY_VS_SIV_INFECTED_DC_UP | 182 | 50 | 17377 | 2626 |
ANKRD13D,SLC2A1,XIAP,CTCF,JMJD6,NANS,DNAJB1,SLC12A9,PARK7,FERMT3,MEGF8,PIK3R2,TIMELESS,C8orf59,TMEM160,SRPK2,NOL12,TELO2,TDP1,GTF3C6,PSRC1,PTPN18,POLR2I,MRPL12,BOLA1,MPG,BORA,USP21,DAPK3,HSPA1B,DDX23,RPL36,NSA2,ZNF862,INF2,TIMM13,POLR2J,WDR11,CLK3,GPS2,STAT6,RPS14,HAGHL,BAZ1B,PRMT7,ST3GAL2,DVL1,NDUFS5,ARRB2,ANAPC4 |
| 1.185e-05 | -11.34 | GSE22103_UNSTIM_VS_GMCSF_AND_IFNG_STIM_NEUTROPHIL_UP | MSigDB lists | GSE22103_UNSTIM_VS_GMCSF_AND_IFNG_STIM_NEUTROPHIL_UP | 182 | 50 | 17377 | 2626 |
MMACHC,IMMT,TXN,PPP1R12A,HJURP,KLHL21,MECP2,WDR13,PMS2,STARD7,AGFG1,EZH1,MXD4,MAPK14,SDHA,FAM8A1,C2orf68,LRRC14,FASTKD3,ZBTB45,NUS1,NOL11,CCP110,PELO,TXLNA,PDS5B,EI24,NSFL1C,AHCYL1,LRRC59,SLC35A1,CCAR1,TTPAL,TACC1,C16orf72,ZNF574,NFATC2,WDR81,KDM1B,CLNS1A,CCDC6,CORO1C,H2AFX,ZDHHC7,CD81,COIL,POT1,MRPL3,ANXA11,RHEBL1 |
| 1.185e-05 | -11.34 | GSE17974_0H_VS_6H_IN_VITRO_ACT_CD4_TCELL_DN | MSigDB lists | GSE17974_0H_VS_6H_IN_VITRO_ACT_CD4_TCELL_DN | 182 | 50 | 17377 | 2626 |
MMACHC,PIGM,URB2,B4GALT5,ADO,UCK2,SLC29A1,SDF2L1,NANS,CHAC2,SNRPD3,IL21R,C14orf119,FLAD1,LYAR,HOMER1,GOT2,CD3EAP,UTP18,GEMIN6,PRADC1,TOP1MT,LRRC59,TMEM126B,SCFD2,UTP15,PSMG1,PITPNB,VDAC1,TXNL4A,TOLLIP,CHCHD6,PRDX1,ALG3,KEAP1,TIMM13,PEX5,CDC16,CCDC86,ORMDL2,PSMD8,ACOX1,DNAJC17,MLYCD,PITPNA,KPNA2,RUVBL2,SNRPG,NANP,TUBB |
| 1.185e-05 | -11.34 | GSE17721_CTRL_VS_POLYIC_12H_BMDC_UP | MSigDB lists | GSE17721_CTRL_VS_POLYIC_12H_BMDC_UP | 182 | 50 | 17377 | 2626 |
ANXA6,GPBP1L1,SEC16A,TFRC,DNAJB9,CDK5,NDUFA2,DAD1,IL6ST,BDH1,XPA,MRPL34,HADHB,BCAP29,CYB5R1,TECR,POC5,IMPA2,MSH6,CFL1,RNF5,PTPN18,RPRD1A,KLF10,KAT7,ERLIN1,FRAT2,ARHGDIB,NFATC2IP,SMC2,CDC23,FANCE,SLC50A1,CCT8,CLNS1A,ASF1B,BTBD1,NUCB1,DHX16,BAZ1B,MDH1,ANP32E,CTSA,PDXK,NANP,CHMP7,GLCCI1,CD81,AAAS,HIGD2A |
| 1.186e-05 | -11.34 | ribose phosphate metabolic process | biological process | GO:0019693 | 379 | 89 | 17256 | 2622 |
COX15,NDUFA5,PPCS,NDUFB6,UQCR10,UCK2,OLA1,UCK1,SLC35B2,EFL1,ADPGK,ATP6V1B2,ATP5PF,SDHA,IMPAD1,ADCY9,PPCDC,UPRT,NDUFB9,SLC26A2,TALDO1,ADCY7,ATP6V0A1,OGDH,NDUFA7,NDUFB1,TAZ,STOML2,HINT1,GUCY1B1,NDUFA11,COX5A,DHTKD1,UQCRH,NUDT11,PFKP,NDUFV2,COX5B,GALK1,NDUFS1,MECP2,RAB23,TKT,NDUFA4,COX4I1,CYCS,ABHD14B,ATP5F1B,NDUFS7,NDUFS4,GART,NDUFV1,NDUFA2,NDUFB4,ATIC,CTPS1,MSH2,TPST1,ATP6V0A2,NDUFS8,CYC1,NDUFA3,AMPD2,TGFB1,RHOA,GUK1,NUDT4,LDHA,ADSL,ATP5MF,PKM,PDE3B,HSPA1B,ADSS,MBIP,ATP5MC3,PARG,PRPS2,COX7A2L,ACLY,COX8A,IMPDH1,ACAT1,NDUFS5,ATP5F1A,GPI,NIPSNAP2,PGAM1,NUDT3 |
| 1.186e-05 | -11.34 | ZNF830 (zinc finger protein 830) | protein interactions | 91603 | 23 | 13 | 17029 | 2761 |
THOC1,XAB2,PPIL2,RAB4A,PPIE,ILF3,AQR,YY1,PCBP1,APPL1,SF3A2,PRPF19,SF3B2 |
| 1.193e-05 | -11.34 | pH reduction | biological process | GO:0045851 | 45 | 19 | 17256 | 2622 |
CLCN3,PPT1,RAB7A,GPR89A,ATP6V0A1,ATP6V1B2,ATP6V0B,ATP6V1D,CLIC4,ATP6V0A2,ATP6V0C,ATP6V1C1,CLN3,CLN6,ATP6V0E1,ATP6V0D1,GPR89B,ATP6V1G1,SNAPIN |
| 1.198e-05 | -11.33 | TMOD3 (tropomodulin 3) | protein interactions | 29766 | 105 | 35 | 17029 | 2761 |
COX15,HNRNPUL2,DHX9,MYH9,CSNK2A1,ATP6V1B2,TWF2,MAP1LC3B,PSMD9,PARK7,USP5,RAD23A,DAPK1,AHCYL1,PABPC1,MYO5A,CDC5L,PSMB7,PSMA1,CAPZA2,PRPF3,ANLN,MCFD2,DHX15,ISG15,PSMC4,INF2,PSMD3,MYO18A,ACTB,PRPF4,RUVBL2,ARRB2,CDK2,LONP2 |
| 1.199e-05 | -11.33 | MORF_GSPT1 | MSigDB lists | MORF_GSPT1 | 49 | 20 | 17377 | 2626 |
HNRNPAB,SCAMP3,NSDHL,CYCS,UTP3,CDC23,TOMM40,VDAC1,CCNB1,PSMD9,MRPL19,SF3B2,HSPA4,MFAP1,ATIC,AHSA1,RAD23B,PPM1G,MRFAP1L1,KPNA2 |
| 1.199e-05 | -11.33 | GCM_IL6ST | MSigDB lists | GCM_IL6ST | 49 | 20 | 17377 | 2626 |
KIF3B,GLT8D1,GORASP1,TACC1,MAP4K4,SIRT2,LANCL1,GFM2,RAB22A,CRKL,NAPG,GOLGA7,MTMR4,IL6ST,GLTP,CLDND1,MYO9A,ATMIN,DYNC1LI2,PACS2 |
| 1.212e-05 | -11.32 | DNA secondary structure binding | molecular function | GO:0000217 | 24 | 13 | 17224 | 2647 |
RAD51C,RAD18,NEIL3,XRCC2,MSH2,XRCC3,HMGB2,YY1,BLM,MEN1,POT1,MSH6,RAD51D |
| 1.214e-05 | -11.32 | intracellular vesicle | cellular component | GO:0097708 | 2281 | 407 | 18223 | 2701 |
CCDC93,TMED7,RAB14,PDCD6IP,ADAM10,ZDHHC8,HEXB,TAP1,AP3M2,TGOLN2,NHLRC3,GYG1,SYNRG,CMTM6,KIFC1,PA2G4,PSMD1,DBNDD1,RABGAP1L,RAB4A,AP1M1,DNM2,AP2B1,MARCH2,KCNAB2,USO1,RHOBTB3,NRAS,ATG9A,AKT2,ARHGAP45,PPFIA3,SLC17A5,MCFD2,RAB22A,PLEKHF2,WAS,TMED10,RPS27A,AXIN1,PRDX5,ITGB1,VIPAS39,ATP6V0C,ARRB2,ANXA11,SVIP,PPIB,HSPH1,DNAJC5,GMFG,SCOC,GGA1,CCZ1,HLA-E,RHOC,RAB23,ACAP1,B4GALT1,MAN2B1,TMED3,ITGB5,APH1B,TMEM165,PSEN1,VPS25,COPG2,WDR48,COPB2,TMEM179B,GNS,CD59,SLC31A1,RPN1,ARPC5,SNX18,ZNRF2,ATP6V0A2,OSTF1,PIKFYVE,MVP,LPCAT1,SYTL3,TMED2,CYFIP1,FTL,PIGT,SIGMAR1,USP10,C1orf35,ADRB2,PKM,GOSR1,MAP2K2,CCT8,RHOB,PI4K2A,XRCC5,DERL1,MAGED2,CAT,SEC31A,SCARB2,OSBPL11,GOLGA2,ACLY,APPL2,ARAP1,GPI,CDK2,HEXA,SNX14,ALS2,EXOC3,RHOG,CYTIP,ANKRD27,ABCA3,GGNBP2,RAB11B,GPR89A,RAC1,VTI1A,OLA1,MON1B,NIT2,NIPA2,BCL2L1,AP1B1,PRKACA,STAM,CPNE3,APP,CD320,CRKL,RAB21,APLP2,SIAH1,MTMR4,TBC1D14,CLCN6,BRI3,CDKN1B,TAP2,TMEM9,TMBIM1,SNX8,ENPP4,CPNE1,CCT2,GOPC,VDAC2,ATP6V0A1,RAB1A,AP4E1,ALDH3B1,CHMP4A,DSN1,JAK1,DDOST,VPS26B,RAB24,WDR7,TICAM1,PDXK,TUBB,DYNC1LI2,ANKRD13D,ANXA6,MANBA,FLOT1,TRAK1,IFT27,RAB11A,HEATR5B,HLA-A,PIP5K1C,EBP,PSMD2,CLIC4,HUWE1,CNN2,ST8SIA2,TPCN1,SPTAN1,PDPK1,DENND1B,DENND4C,HEBP2,PACS1,KCNQ1,PICALM,SPPL2B,PRDX1,SH3GLB1,YIF1A,NUCB1,TMEM127,HGS,MAGT1,PRDX3,WNT5B,FAM3C,PML,PSAP,WDR91,YWHAH,VPS29,SNAPIN,MIB2,ADA2,COPA,SNX15,PTP4A3,SND1,AGFG1,UBQLN2,MAP1LC3B,RUFY1,BECN1,MAPK14,SEC16A,KCMF1,PCYOX1L,DST,RAB8A,RAP1A,CDC42,AP3S2,RAB35,SRI,ZFYVE27,RP2,CARMIL1,CYSTM1,EZR,ARHGDIB,RAB5B,OPTN,NECAP2,DPYSL3,CXXC4,TBC1D17,AGPAT2,GRIPAP1,CRCP,CAB39,ARRDC1,CLU,VPS4A,ROCK1,DVL1,CLN3,C2CD5,ATP6V0E1,CAPN1,NUMB,STARD3NL,UBE2D3,TBC1D12,TMUB1,AGTRAP,TM9SF4,NKD2,CDIP1,LAMTOR3,ASAH1,KLC1,RACGAP1,CDK13,RAB6A,RAPGEF6,RINL,AHCY,ATP6V0D1,KDELR1,VOPP1,ABHD2,CREG1,ARMC8,APPL1,RMC1,CAND1,NAP1L1,TMEM168,SNAP23,LAMTOR4,SIAH2,YWHAZ,CTSA,EHD4,ECPAS,UNC13C,NIPA1,WASF2,SNX27,CHMP2A,CORO7,TRAF7,GNPNAT1,DYNLL1,SLC2A1,COPE,ZFYVE21,RRAGC,ATP6V1B2,BCAP31,ATP6V0B,MDM2,WDR44,SAR1A,CORO1A,CYB5R1,APOOL,LMAN1,CLTB,PDIA6,F2R,GM2A,DVL2,EBAG9,CHP1,SNX25,CLCN3,UBQLN4,TIMP2,PPT1,RAB7A,PPIE,PSMB7,SLC26A6,WIPF1,BICD2,CHMP2B,TOLLIP,PEF1,ATP1A1,SURF4,VPS26C,TAB2,CLK3,SCAP,PSMD3,CANT1,AP1S1,ANP32E,CHMP4B,SCARB1,MAPK1,LTA4H,AP2S1,CHID1,ABCA1,TMEM33,MIF,SLC30A9,GOLIM4,PDAP1,SCYL1,SRGN,VPS45,TMX3,CHIC2,GGA2,AP3S1,SCYL2,MFSD10,TFRC,FZD6,SPPL2A,FERMT3,KIF5B,HERC3,FGFR3,CTSS,SLC1A4,SEC24C,ZDHHC13,ARHGEF2,YIF1B,CAMK2G,MYO5A,TGFB1,MLEC,RHOA,FAM49B,SNX2,RFFL,WDR81,NEU1,MAPK3,HSPA1B,CTSL,HLA-B,RAB18,SEC23IP,ATP6V1D,PDCD6,GOLGA7,SNAP29,PGRMC1,IMPDH1,PKD2,ATP6V1C1,RPS6KC1,CHMP7,PGAM1 |
| 1.215e-05 | -11.32 | GSE360_CTRL_VS_M_TUBERCULOSIS_MAC_UP | MSigDB lists | GSE360_CTRL_VS_M_TUBERCULOSIS_MAC_UP | 187 | 51 | 17377 | 2626 |
NUP188,ADD1,CHERP,URB2,RPS6KA1,ADO,UBXN1,AP3M2,COX4I1,CDIPT,DAZAP2,GIT2,CD59,VAV1,FARSA,NDUFV1,PSMD1,SHC1,ARF5,KIF13B,BANF1,XRCC2,CYB5R1,NAP1L4,MRPL40,AHCYL1,PACS2,VOPP1,MIOS,TSTA3,GBA,FRAT2,NUTF2,API5,COMMD4,MAK16,CDK11A,PFDN5,SERTAD2,PPP2R5A,DUSP3,PTPN7,UQCRH,RUVBL2,COPS6,CLN3,PLOD3,TRAF5,ARRB2,LTA4H,AP2S1 |
| 1.215e-05 | -11.32 | GSE29618_LAIV_VS_TIV_FLU_VACCINE_DAY7_BCELL_DN | MSigDB lists | GSE29618_LAIV_VS_TIV_FLU_VACCINE_DAY7_BCELL_DN | 187 | 51 | 17377 | 2626 |
SLC12A7,MBD1,ZNF207,TMBIM4,RPLP2,MRPS15,UQCR10,RAF1,CDK2AP2,ARFIP2,IRF3,GYG1,RAB6A,ZNF267,MAPK14,CAPN2,FARSA,RBM23,NDUFB4,BANF1,CORO1A,CITED2,GNAI2,FAM3A,KDELR1,EBAG9,ENPP4,ERCC1,GUK1,ELL2,RPL6,TUFM,RPS24,CAPZA2,KCNQ1,EIF3H,RPL37,MID1IP1,PLAA,PPP2R5A,SERF2,CCDC86,RPL32,SETD3,NCOA1,RBPJ,YWHAH,FAM208A,RPS26,NRBP1,NXT2 |
| 1.215e-05 | -11.32 | GSE17721_CTRL_VS_LPS_4H_BMDC_UP | MSigDB lists | GSE17721_CTRL_VS_LPS_4H_BMDC_UP | 187 | 51 | 17377 | 2626 |
NCOR2,C19orf53,TMEM203,MDH2,ANKH,HNRNPUL2,RAC1,CENPF,NDUFA4,MYO9B,SEC16A,LCLAT1,KCMF1,PNO1,RPA2,STRBP,KLF16,IL6ST,BDH1,GEMIN6,CTR9,MRPL11,MGAT5,TMEM14C,ELOF1,ELOVL5,PPP1R18,AATF,IDH3A,SLC26A6,RPL6,FBXO9,HTATIP2,DNAJC9,NDUFA7,ADRB2,DIDO1,NEU1,MAPK3,SUPT16H,MRPL2,NSF,LIMK1,H2AFX,RNF38,CRCP,NDUFS5,RBBP4,RPS26,SLC25A39,STARD3NL |
| 1.215e-05 | -11.32 | GSE360_CTRL_VS_T_GONDII_MAC_UP | MSigDB lists | GSE360_CTRL_VS_T_GONDII_MAC_UP | 187 | 51 | 17377 | 2626 |
MPHOSPH8,TMEM184B,COPA,DAP,RAE1,TSC22D3,MYO9B,PSMD9,FOXO3,PAIP1,RPL11,FKBP1A,SH3BP1,DAD1,FBXO7,ANXA5,NDUFS8,CYB5R1,NAP1L4,FAM3A,TRIM14,KCNAB2,MED22,VOPP1,CCDC57,CYFIP1,FAM172A,ATG9A,TSPAN31,LY6E,MPG,CHAF1A,GLOD4,MYO1F,SDHB,TPD52L2,AHNAK,BRWD1,POLR2J,GPS2,RPS27A,ACOX1,ZNF268,BTF3,PDXK,PLOD3,PDCD11,LTA4H,AP2S1,ATP6V0E1,CAPN1 |
| 1.215e-05 | -11.32 | GSE22886_NAIVE_CD4_TCELL_VS_NEUTROPHIL_UP | MSigDB lists | GSE22886_NAIVE_CD4_TCELL_VS_NEUTROPHIL_UP | 187 | 51 | 17377 | 2626 |
C9orf78,LYRM4,C19orf53,ST13,SCAMP3,SUCLG1,SRSF6,TMEM109,SMARCA4,SUPT7L,METTL3,HMG20A,HDDC2,SLC25A36,CAPN2,GSDMB,KLHL20,ZNHIT6,FBXO7,RAB4A,BRD7,SUCLG2,JOSD1,MDFIC,CDC25B,SEH1L,PRPF19,SRSF10,NAGPA,DDX28,PSMB7,TUFM,ITM2A,NUTF2,CDC23,MCFD2,MACF1,TARS,MAT2A,MAP3K4,TSC1,EPRS,ZNF862,IARS2,MDH1,SRSF3,PIEZO1,PTDSS1,ZC3HAV1,ADNP2,SSRP1 |
| 1.215e-05 | -11.32 | GSE29949_MICROGLIA_BRAIN_VS_MONOCYTE_BONE_MARROW_DN | MSigDB lists | GSE29949_MICROGLIA_BRAIN_VS_MONOCYTE_BONE_MARROW_DN | 187 | 51 | 17377 | 2626 |
MBD1,NDUFB6,PTTG1,DHX8,SLC25A12,HMGN3,PPP3CB,B4GALT4,ATP6V1B2,IFT27,GGPS1,CCDC28A,FANCI,NDUFS4,RB1,ZNF473,SP100,LPIN2,PDS5B,MDFIC,GEMIN4,APOOL,GTF2H2,DNMT1,HNRNPM,EBAG9,USP34,POU2AF1,PGAP2,ZNF84,PGGT1B,ITM2A,POLG2,RAB22A,MTR,ISG15,PRIM1,KPNA1,RPS27A,PRDX3,PRPS2,CTBS,SIAH2,IARS2,ANP32E,TAF12,LONP2,GCSH,IFI16,NUMB,DDX52 |
| 1.215e-05 | -11.32 | GSE42724_MEMORY_BCELL_VS_PLASMABLAST_DN | MSigDB lists | GSE42724_MEMORY_BCELL_VS_PLASMABLAST_DN | 187 | 51 | 17377 | 2626 |
C1orf74,CASP6,NF1,UBR2,ANKH,TKT,RGS2,RUFY1,FOXO3,CMTM6,SMC3,BDH1,PHTF1,KIFAP3,CITED2,RNF5,ALDH9A1,SRSF10,SNX8,SEPT9,RNASEH2C,GALC,EID1,TACC1,PGGT1B,AKT2,CIRBP,ATP6V0A1,EMP3,GLO1,SRSF5,PRKRA,STX16,MBD3,GLOD4,ADSS,OSBPL11,POLR2J,TXNDC16,SCAP,CORO1C,PRPS2,GLG1,ACAT1,ZFP90,NCOA1,SCARB1,TFDP2,PDLIM5,PURA,PDCD4 |
| 1.215e-05 | -11.32 | GSE7460_CD8_TCELL_VS_TREG_ACT_DN | MSigDB lists | GSE7460_CD8_TCELL_VS_TREG_ACT_DN | 187 | 51 | 17377 | 2626 |
SKA3,CDCA3,HAUS4,SLC29A1,PMF1,SNN,SPAG5,UBLCP1,SSR1,ANKRD28,RB1,SNUPN,SMC3,LRRC8D,UTP18,DNAAF2,UBA5,NUP107,PDS5B,TIMELESS,ANKRD13C,CENPM,MRPL40,OSTC,MYBL1,TACC3,HNRNPM,TMX1,SRSF10,COPS8,POLR2D,DDX20,NUSAP1,AURKB,DIDO1,VDAC1,ANLN,CBFA2T2,RAD54B,ADSS,ALG3,DAP3,KIF18A,CDC27,TMED10,UEVLD,QRSL1,SPCS3,GEN1,TSEN15,NXT2 |
| 1.215e-05 | -11.32 | GSE3982_MEMORY_CD4_TCELL_VS_TH2_DN | MSigDB lists | GSE3982_MEMORY_CD4_TCELL_VS_TH2_DN | 187 | 51 | 17377 | 2626 |
TMEM106C,POLR2K,ADO,RRM1,CDCA8,FLOT1,CSNK2A1,BLM,NDUFS4,DTL,OIP5,IRF4,PA2G4,CCNA2,EIF2S2,PPCDC,MSH2,PARL,AHCY,RNASEH2A,GINS1,PPIF,CCT2,ERCC1,NASP,PBK,CPOX,MRPL12,KIF15,VDAC2,RRM2,NUSAP1,SMC2,USP22,NUTF2,VDAC1,MCM2,KIF11,RHOB,XRCC5,RAD51C,GALNT2,ELMO1,PRDX3,PSMD8,TFDP1,H2AFX,SLC16A1,CAB39,CDK2,SSRP1 |
| 1.215e-05 | -11.32 | VEGF_A_UP.V1_DN | MSigDB lists | VEGF_A_UP.V1_DN | 187 | 51 | 17377 | 2626 |
SLC30A9,RECQL,ST13,UGP2,B4GALT5,DBF4,C5orf30,KIF23,CCNB1,RGS2,MRPL19,PNO1,SPAG5,PAPOLA,MBD4,RAP1A,PPIG,ATIC,TRMU,ATP13A3,NOC2L,KIF22,OSTF1,RP2,MYO5A,SMC4,BAK1,MKLN1,NEK7,DHX29,AMD1,RRM2,NUP155,BCLAF1,KIF11,RDH11,CCDC86,UAP1,CDC27,BIRC5,MAFK,MAPK6,SEL1L,ADAM9,FKBP5,ACADM,RRS1,XRCC4,CCNB2,LRP8,USP13 |
| 1.223e-05 | -11.31 | MODULE_239 | MSigDB lists | MODULE_239 | 112 | 35 | 17377 | 2626 |
TOMM20,SF3B1,TOR1AIP1,DHX9,CDK13,RAB6A,ASXL2,BCAP31,SSR1,APLP2,ARPC5,IL6ST,AP2B1,ORC3,N4BP2,HDHD2,TMED2,SP3,ELOVL5,RHOBTB3,TACC1,LRRC8A,GLO1,PTTG1IP,GIGYF1,ADSS,IDE,PPP2R5A,TWSG1,TMED10,NSF,ITGB1,CAB39,DDX5,RTN3 |
| 1.230e-05 | -11.31 | negative regulation of cell cycle G1/S phase transition | biological process | GO:1902807 | 125 | 38 | 17256 | 2622 |
CDK2AP2,CCNB1,CNOT11,CDC73,CNOT3,RFWD3,RPA2,RB1,PCNA,MDM2,PTEN,CENPJ,FBXO7,GTSE1,BRD7,CDKN1B,BCL2,CNOT6L,CTDSP2,CARM1,PLK3,PRKDC,BTG2,MEN1,SOX4,PRMT2,CNOT9,RBL1,RPS27A,E2F4,TFDP1,PML,E2F1,CNOT6,PKD2,CHEK2,TFDP2,CDK2 |
| 1.231e-05 | -11.30 | NADH dehydrogenase activity | molecular function | GO:0003954 | 41 | 18 | 17224 | 2647 |
NDUFA5,NDUFV2,NDUFS1,NDUFB6,NDUFAF2,NARF,NDUFA4,NDUFA7,NDUFB1,NDUFS7,NDUFS4,NDUFV1,NDUFA2,NDUFB4,NDUFB9,NDUFS8,NDUFS5,NDUFA3 |
| 1.237e-05 | -11.30 | methyltransferase complex | cellular component | GO:0034708 | 96 | 31 | 18223 | 2701 |
METTL1,MAX,ZFP64,SNRPB,SUZ12,CXXC1,TRMT6,TEX10,WDR82,EZH1,SNRPD3,WDR5,KMT2C,MEN1,PAGR1,METTL3,CLNS1A,USF1,ERH,EPOP,METTL14,WDR4,PRDM4,ZNF335,KMT2B,H2AFY,RUVBL2,SNRPG,RBBP4,TAF6,HDAC2 |
| 1.238e-05 | -11.30 | NDUFA8 (NADH:ubiquinone oxidoreductase subunit A8) | protein interactions | 4702 | 61 | 24 | 17029 | 2761 |
NDUFV2,NDUFS1,NDUFB6,TIMMDC1,RAB7A,VDAC2,CHCHD2,NDUFA4,NDUFA7,CNTROB,NDUFB1,VDAC1,CHCHD6,NDUFS7,NDUFS4,CHCHD3,NDUFV1,NDUFA2,NDUFB4,NDUFA11,NDUFB9,NDUFS8,NDUFA3,CAMK2G |
| 1.241e-05 | -11.30 | GSE22886_NAIVE_BCELL_VS_MONOCYTE_DN | MSigDB lists | GSE22886_NAIVE_BCELL_VS_MONOCYTE_DN | 192 | 52 | 17377 | 2626 |
RHOG,RAB14,CHMP2A,IMMT,FEZ2,NDUFS1,CKLF,RPS6KA1,SRGN,HEXB,TKT,MOGS,KLF13,ASAH1,GYG1,NOTCH2,TWF2,CSNK1A1,GNS,VASP,ATG3,HADHB,H2AFY,METTL9,TALDO1,TIMM8B,FTL,TIMP2,TRIM8,KLF10,CREG1,MAPKAPK3,PPT1,ATXN1,MAP7D1,PTTG1IP,PICALM,NEU1,MYO1F,ATP1A1,RBM47,DUSP3,CERS6,SNAP29,SEL1L,NUP62,ATP6V0C,ASNA1,PSAP,ZMIZ1,ARRB2,RTN3 |
| 1.241e-05 | -11.30 | GSE23321_CD8_STEM_CELL_MEMORY_VS_EFFECTOR_MEMORY_CD8_TCELL_UP | MSigDB lists | GSE23321_CD8_STEM_CELL_MEMORY_VS_EFFECTOR_MEMORY_CD8_TCELL_UP | 192 | 52 | 17377 | 2626 |
EXOC3,FGFR1OP,NAT9,PLXNC1,SRGN,ADO,TMEM97,PLAGL2,KLHL18,GYG1,S1PR2,SNN,EPHX2,METTL3,FANCI,ZNF92,EBP,HERC3,ZNF428,FARSA,NRF1,RAB4A,CTR9,CDC25B,ALDH9A1,ABCC1,NUDC,KDM3B,CLPTM1,CPNE1,PPP3CA,BRD4,ZNF202,TUFM,NFATC2IP,NUTF2,KLF6,ABCF1,BRMS1,ALG3,UPF1,POLE,ELMO1,CAPN7,NFIL3,PTPN7,UHRF2,ACADM,MAPK1,EYA2,SMNDC1,USP13 |
| 1.241e-05 | -11.30 | GSE15139_GMCSF_TREATED_VS_UNTREATED_NEUTROPHILS_DN | MSigDB lists | GSE15139_GMCSF_TREATED_VS_UNTREATED_NEUTROPHILS_DN | 192 | 52 | 17377 | 2626 |
RAB14,DNAJC2,LIME1,SCOC,GNPDA1,FAM129A,TRAK1,INO80E,PDCD7,TMEM165,C19orf48,SDHA,WRB,SEC11A,RFWD3,NRF1,PA2G4,CWC27,ATG3,CS,KIFAP3,UPF2,KNTC1,CENPM,ALDH18A1,FTSJ3,NCOA2,MYO5A,RBM15B,SRSF10,PLK1,SRP72,NRAS,KLF10,DHX29,NOL8,CPOX,NSUN2,TBRG4,ESYT1,CCNF,KLF6,SRSF1,GEMIN5,TRAM2,PWWP2B,PDLIM1,POLE,CCDC6,PPM1G,ZFP90,CHID1 |
| 1.241e-05 | -11.30 | GSE24574_BCL6_HIGH_TFH_VS_TFH_CD4_TCELL_DN | MSigDB lists | GSE24574_BCL6_HIGH_TFH_VS_TFH_CD4_TCELL_DN | 192 | 52 | 17377 | 2626 |
PNISR,RPLP2,HLA-E,DNAJB2,SRSF6,UBXN1,MYH9,BTN3A1,NOTCH2,CDIPT,RGS2,DAZAP2,RGS1,MOAP1,CAPN2,ADD3,ITGB8,IL6ST,AKAP8,JOSD1,ATG13,PIK3IP1,MOB1A,USP34,RPL29,CYTH1,BTG2,KAT7,CIRBP,EZR,MCL1,EIF3G,RBM38,EIF3A,RXRB,MAGED2,RPL37,TRAM2,RPL32,CHD3,GPS2,RPS27A,AXIN1,RBMS1,DDX5,NCOA1,PPP6R2,H3F3A,SNRNP70,RNF139,TOB1,TERF1 |
| 1.241e-05 | -11.30 | GSE360_T_GONDII_VS_M_TUBERCULOSIS_MAC_UP | MSigDB lists | GSE360_T_GONDII_VS_M_TUBERCULOSIS_MAC_UP | 192 | 52 | 17377 | 2626 |
KCTD7,NCOR2,NUP188,TMEM184B,CHERP,UBN1,KLHL21,CDT1,TKT,CDIPT,PABPC4,SAC3D1,TFAP4,IRF4,HOMER1,ATP2A2,INPP5A,ATIC,ADCY9,TXLNA,MSH2,PIK3IP1,NAP1L4,TP53BP2,CPSF4,PABPC1,PACS2,IMPA2,MSH6,FAM172A,EZR,DNAJC9,PCGF1,MCM2,TRIM28,IRF5,NMT2,STOML2,PRIM1,UBTF,PON2,TPD52L2,BRD2,CERS6,GADD45B,KHSRP,USP20,RUVBL2,HEXA,TRAF5,PTDSS1,B4GALT2 |
| 1.241e-05 | -11.30 | GSE360_DC_VS_MAC_B_MALAYI_LOW_DOSE_DN | MSigDB lists | GSE360_DC_VS_MAC_B_MALAYI_LOW_DOSE_DN | 192 | 52 | 17377 | 2626 |
MIF,USP7,PLXNC1,ADD1,POLR2K,TRIP10,URB2,MAGED1,CDK2AP2,DCTN2,BTN3A1,PMVK,PABPC4,HDDC2,CNOT3,FANCL,SIAH1,SIVA1,RAB4A,CYB5R1,CNPY3,SLC25A1,TIMP2,SEC61B,GNG7,PPIE,WDR18,JTB,EMP3,GLO1,GORASP2,FAM50B,TOMM40,MBD3,DDX17,SEC31A,HGS,WAS,PPP2R5A,LTBP4,AGPAT2,BRD2,PFDN4,CHD3,PSMD8,E2F4,SIAH2,ATXN2L,TICAM1,WIPI2,TCOF1,ZBTB24 |
| 1.241e-05 | -11.30 | GSE21670_UNTREATED_VS_TGFB_IL6_TREATED_STAT3_KO_CD4_TCELL_UP | MSigDB lists | GSE21670_UNTREATED_VS_TGFB_IL6_TREATED_STAT3_KO_CD4_TCELL_UP | 192 | 52 | 17377 | 2626 |
HIVEP3,FGFR1OP,GPR89A,RACGAP1,NUF2,SLC35B1,TCF19,STMN1,LCLAT1,REEP5,RGS1,FANCI,PRNP,IRF4,PSMD1,CCNA2,MCM5,EI24,KIF22,MDFIC,ALDH18A1,MGAT5,GINS1,MAPKAPK3,POLK,PBK,MKI67,ZBED5,RRM2,TOR1AIP2,CDC6,NUSAP1,UBE4B,ODC1,GFER,ASF1B,GLOD4,IDE,ATAD2,KIF18B,DSN1,POLE,CDCA5,AEN,RBPJ,RUFY3,EHD4,TFDP2,CCNB2,GCSH,GPR89B,TIGD2 |
| 1.241e-05 | -11.30 | GSE1925_3H_VS_24H_IFNG_STIM_IFNG_PRIMED_MACROPHAGE_DN | MSigDB lists | GSE1925_3H_VS_24H_IFNG_STIM_IFNG_PRIMED_MACROPHAGE_DN | 192 | 52 | 17377 | 2626 |
MIF,MIF4GD,UGP2,CASP6,RAC1,CDCA8,UCK1,CDC42SE2,DNAJB1,COMMD5,PRPF39,OAT,STMN1,FAM8A1,WDR48,WRNIP1,CRKL,INTS7,TIMM23,NUP107,PRC1,TAP2,AFF1,CLTB,DNMT1,CTDSP2,ABCC5,ATP6V1G1,PPIF,SLC39A9,CDC123,NSDHL,BTG2,LRBA,WDHD1,DNAJC9,C9orf40,ASF1B,TFEB,PTPRF,FBXO21,CDKN2AIPNL,ETS2,BIRC5,AXIN1,HNRNPH3,STK38,PRPS2,COX7A2L,HMGB2,KPNA2,VPS4A |
| 1.250e-05 | -11.29 | GCN1 (GCN1, eIF2 alpha kinase activator homolog) | protein interactions | 10985 | 101 | 34 | 17029 | 2761 |
NDUFA5,STAU1,COPA,HARS,SUZ12,MAGED1,PTP4A3,BRCA1,MCM2,SDHA,SRSF1,INF2,PDCD6,EIF2S2,NEK6,C4orf3,SAFB,EIF2D,ZNF746,PGRMC1,ACAT1,TRA2B,ANXA5,CRY2,XRCC3,MAST2,WIPI2,SRSF3,SNRNP70,CLN3,CDK2,DNMT1,PHKG2,CDC5L |
| 1.250e-05 | -11.29 | BRCA2 (BRCA2, DNA repair associated) | protein interactions | 675 | 101 | 34 | 17029 | 2761 |
BCCIP,IER2,NSMCE4A,MAGED1,PMS2,FANCI,RAD23A,PCNA,SMC3,CCNA2,BABAM2,PDS5B,MCPH1,PLK1,TOP3A,RFXANK,MIER2,BRCA1,AURKB,FANCE,USP21,RPA1,PPP2CA,RAD51C,SMAD2,KEAP1,DSN1,PALB2,PSMD3,H2AFX,XRCC3,CHEK2,USP11,CDK2 |
| 1.259e-05 | -11.28 | GO_NADH_DEHYDROGENASE_ACTIVITY | MSigDB lists | GO_NADH_DEHYDROGENASE_ACTIVITY | 38 | 17 | 17377 | 2626 |
NDUFA5,NDUFV2,NDUFS1,NDUFB6,NDUFAF2,NDUFA4,NDUFA7,NDUFB1,NDUFS7,NDUFS4,NDUFV1,NDUFA2,NDUFB4,NDUFS8,NDUFB9,NDUFS5,NDUFA3 |
| 1.263e-05 | -11.28 | GO_GENE_SILENCING | MSigDB lists | GO_GENE_SILENCING | 197 | 53 | 17377 | 2626 |
MBD1,DNMT3A,NUP188,H2AFZ,POLR2K,UBR2,RAE1,MECP2,NUP54,SIRT2,SND1,SRRT,METTL3,RBM4,NUP205,CNOT3,HNRNPA2B1,NUP210,MBD2,NUP107,H2AFY,NUP153,CNOT6L,STAT3,TNRC18,DNMT1,NUP85,PABPC1,SEH1L,POLR2I,POLR2L,POLR2G,BAZ2A,POLR2D,NUP155,ARID1A,KCNQ1,PRKRA,H2AFV,MBD3,POLR2A,DOT1L,SMAD2,POLR2J,DGCR8,H2AFX,NUP62,CNOT6,BEND3,H3F3A,SMAD1,HDAC2,AAAS |
| 1.263e-05 | -11.28 | GO_G1_DNA_DAMAGE_CHECKPOINT | MSigDB lists | GO_G1_DNA_DAMAGE_CHECKPOINT | 69 | 25 | 17377 | 2626 |
PLK3,BTG2,PRKDC,SOX4,CCNB1,RBM38,CNOT3,RPA2,RFWD3,PCNA,MDM2,RPS27A,CENPJ,E2F4,TFDP1,E2F1,PML,CDKN1B,GTSE1,CNOT6,CHEK2,CNOT6L,TFDP2,CDK2,CARM1 |
| 1.263e-05 | -11.28 | GNF2_KPNB1 | MSigDB lists | GNF2_KPNB1 | 69 | 25 | 17377 | 2626 |
DDX47,SNRNP200,SUZ12,EIF3D,HNRNPF,PSMA1,SNRPD3,DHX15,SRSF1,XRCC5,SF3B2,MAP3K4,SMC3,HSPB11,SYNCRIP,NOL11,HNRNPR,RBMX,U2SURP,NUP153,TARDBP,SRSF3,FBL,HNRNPM,SRSF10 |
| 1.265e-05 | -11.28 | KEGG_VIBRIO_CHOLERAE_INFECTION | MSigDB lists | KEGG_VIBRIO_CHOLERAE_INFECTION | 53 | 21 | 17377 | 2626 |
SEC61B,SEC61G,ATP6V0A1,ARF1,KCNQ1,ATP6V1B2,PRKACA,GNAS,ATP6V0B,ATP6V1D,SEC61A1,ADCY9,ATP6V0A2,ATP6V0C,ACTB,ATP6V1C1,SLC12A2,ATP6V0E1,ATP6V0D1,KDELR1,ATP6V1G1 |
| 1.267e-05 | -11.28 | damaged DNA binding | molecular function | GO:0003684 | 68 | 25 | 17224 | 2647 |
ERCC1,POLK,DCLRE1C,BRCA1,BLM,MPG,NEIL2,RAD23A,XRCC5,RPA1,RPA2,PCNA,RAD18,NEIL3,XPA,RAD23B,MSH2,H2AFX,CRY2,HMGB2,POT1,OGG1,MSH6,DDB1,POLQ |
| 1.271e-05 | -11.27 | BROWNE_HCMV_INFECTION_14HR_UP | MSigDB lists | BROWNE_HCMV_INFECTION_14HR_UP | 149 | 43 | 17377 | 2626 |
CCDC93,FGFR1OP,GCLM,MAX,UBN1,TSC22D3,DBF4,KLHL18,JMJD6,TAF6L,SAFB2,SRRT,PNO1,ATP6V0B,NFATC3,EIF4A3,ZNF200,UPF2,ATF2,UBE2M,MORC3,ABCC5,ZNF202,AMD1,CDC6,PRPF3,CCNF,DDX39A,TARS,NEU1,BRMS1,UPF1,CERS6,LUC7L3,CEBPG,SIAH2,ANP32E,ATP6V1C1,CDK2,SMURF1,POT1,PRPF4B,ADNP2 |
| 1.272e-05 | -11.27 | CCAWYNNGAAR_UNKNOWN | MSigDB lists | CCAWYNNGAAR_UNKNOWN | 135 | 40 | 17377 | 2626 |
GOLPH3L,PLXNC1,PHB2,RAB6A,CCNB1,PCNA,SHC1,MED8,ZNRF2,MTMR4,IL6ST,TTC9C,PDS5B,DNM2,AKR1B1,YBX1,PRADC1,GNAI2,RLIM,CPNE1,PIGT,APH1A,POLR3GL,SOX4,KDM3A,ARL17A,NCDN,RHOB,DHX57,HHEX,MAGT1,TMED10,E2F4,RBMS1,UQCRH,H3F3A,BRWD3,CDK2,TERF1,NXT2 |
| 1.275e-05 | -11.27 | GSE38696_LIGHT_ZONE_VS_DARK_ZONE_BCELL_UP | MSigDB lists | GSE38696_LIGHT_ZONE_VS_DARK_ZONE_BCELL_UP | 168 | 47 | 17377 | 2626 |
SLC12A7,DDX47,ADAM10,SF3B1,XIAP,RAB23,TIA1,DHX8,GMCL1,SEC16A,COMMD8,RAPGEF6,PIP4K2A,HMG20A,CDC73,PAIP2,VAV1,ARHGEF2,SS18L1,CNOT6L,FRMD8,TELO2,PPP3CA,PBXIP1,BTAF1,DENND4C,MAP4K4,EHMT1,ARHGEF12,DIDO1,PPWD1,AZI2,TANC1,MACF1,DHX15,ARHGAP15,GLOD4,DDX17,CHD3,STK38,LUC7L3,HPS5,STAT1,SAMD8,CHID1,ANAPC4,HDAC2 |
| 1.279e-05 | -11.27 | GTF2E2 (general transcription factor IIE subunit 2) | protein interactions | 2961 | 118 | 38 | 17029 | 2761 |
DNAJC2,UGP2,SND1,HDGFL2,PMVK,SRRT,APP,UBLCP1,GTF2F1,MCTS1,OIP5,MDM2,PDCD10,PPP1R8,PPME1,XPA,PTPN11,DNM2,TACC3,CSTF1,GINS1,RPRD1A,FAM49B,HMGN5,MTA2,WDHD1,ADSL,EIF2A,POLR2A,GINS4,SUPT16H,DUSP3,TPP2,EXOC4,CAB39,NUP62,ZRANB2,SPRYD4 |
| 1.287e-05 | -11.26 | ER to Golgi vesicle-mediated transport | biological process | GO:0006888 | 201 | 54 | 17256 | 2622 |
TMED7,COPA,GORASP1,DYNLL1,COPE,DCTN2,ANK3,VTI1A,TMED3,SEC16A,BCAP31,COPG2,COPB2,ANKRD28,CD59,SAR1A,RAB35,SEC24C,PPP6C,CAPZA1,YIF1B,BCAP29,LMAN1,TFG,PPP6R1,TMED2,PREB,DCTN1,SPTAN1,KDELR1,USO1,TMEM115,TRAPPC9,GOPC,CUL3,COG1,CAPZA2,MCFD2,RAB1A,GOSR1,PEF1,ARF4,YIF1A,SEC31A,SEC23IP,PDCD6,GOLGA2,NSF,TMED10,MIA2,PPP6R3,NRBP1,DYNC1LI2,CSNK1D |
| 1.289e-05 | -11.26 | protein localization to nuclear envelope | biological process | GO:0090435 | 8 | 7 | 17256 | 2622 |
PLK1,NUP155,TOR1AIP2,NUTF2,OSBPL8,INTS13,NUP54 |
| 1.295e-05 | -11.25 | REACTOME_ORC1_REMOVAL_FROM_CHROMATIN | MSigDB lists | REACTOME_ORC1_REMOVAL_FROM_CHROMATIN | 65 | 24 | 17377 | 2626 |
PSMA8,CDT1,PSMB7,PSMA1,CDC6,ORC1,MCM2,PSMD9,PSMB9,PSMB3,PSMC4,PSMD2,RB1,PSMA6,CCNA2,PSMD1,RPS27A,PSMD8,PSMD3,MCM5,CDKN1B,ORC3,CDK2,PSMC1 |
| 1.295e-05 | -11.25 | MOREAUX_B_LYMPHOCYTE_MATURATION_BY_TACI_DN | MSigDB lists | MOREAUX_B_LYMPHOCYTE_MATURATION_BY_TACI_DN | 65 | 24 | 17377 | 2626 |
CCT2,NASP,PPP1R12A,LAP3,PRKDC,MRPL43,KLF13,RACGAP1,EBNA1BP2,IP6K2,CDC23,MCM2,TMEM165,EIF3G,C1orf131,CHMP4A,KEAP1,IARS,CHCHD1,ZNF367,PSMD8,EFTUD2,SLC16A1,TIMM50 |
| 1.309e-05 | -11.24 | FYCO1 (FYVE and coiled-coil domain containing 1) | protein interactions | 79443 | 50 | 21 | 17029 | 2761 |
CCT2,CYLD,FOXK1,GOPC,RAF1,CCZ1,ADO,MON1B,KIF23,MAP1LC3B,APP,RMC1,LMNA,RPA1,KIF5B,RPA2,MAP4,MLYCD,SASS6,SGF29,CCAR1 |
| 1.312e-05 | -11.24 | CDT1 (chromatin licensing and DNA replication factor 1) | protein interactions | 81620 | 65 | 25 | 17029 | 2761 |
TRAPPC13,KAT7,CDT1,CUL1,CDC6,ORC1,CDC23,CCNB1,MCM2,MAPK14,FOXO3,DTL,PCNA,CCNA2,TIMM13,DGCR8,TFDP1,BAZ1B,ANAPC7,KPNA2,CDK2,ANKHD1,FAF1,DDB1,CDC5L |
| 1.312e-05 | -11.24 | RNF168 (ring finger protein 168) | protein interactions | 165918 | 65 | 25 | 17029 | 2761 |
UBE2D3,USP7,EWSR1,H2AFZ,TRIP12,FOXM1,KDM4A,POC1A,SUMO2,WBP2,DHX9,MKI67,USP10,DHX15,PABPC4,KIF5B,PCM1,PALB2,H2AFX,ECPAS,PDCD11,RPRD1B,HNRNPM,TACC3,DCTN1 |
| 1.312e-05 | -11.24 | MRPS5 (mitochondrial ribosomal protein S5) | protein interactions | 64969 | 65 | 25 | 17029 | 2761 |
NOL12,MZT1,RBM42,MRPS2,MRPS15,RPL6,TUFM,MRPS26,ILF3,CUL3,FLOT1,MRPS10,LUC7L,CAND1,SDHB,DDX56,DAP3,GALNT2,HNRNPR,RPL17,CORO1C,MRPS27,TRMT10B,ZC3H3,CCDC59 |
| 1.319e-05 | -11.24 | KEGG_PARKINSONS_DISEASE | MSigDB lists | KEGG_PARKINSONS_DISEASE | 99 | 32 | 17377 | 2626 |
COX5B,NDUFA5,NDUFV2,NDUFS1,NDUFB6,UQCR10,VDAC2,NDUFA4,CYCS,COX4I1,NDUFA7,NDUFB1,VDAC1,SLC25A5,SDHA,PARK7,NDUFS7,NDUFS4,SDHB,NDUFV1,NDUFA2,NDUFB4,COX7A2L,COX8A,COX5A,NDUFS8,NDUFB9,UQCRH,NDUFS5,CYC1,NDUFA3,HTRA2 |
| 1.319e-05 | -11.24 | GSE17974_0H_VS_48H_IN_VITRO_ACT_CD4_TCELL_DN | MSigDB lists | GSE17974_0H_VS_48H_IN_VITRO_ACT_CD4_TCELL_DN | 173 | 48 | 17377 | 2626 |
INTS2,MMACHC,CHMP2A,PIGM,CKLF,DHPS,CENPF,UCK2,CSNK2A1,SNRPD3,TMEM165,RMI1,BZW2,MAD2L2,EBP,KIFC1,HNRNPA2B1,FAM192A,SNRNP25,PDCD10,CENPJ,RIMS3,PRC1,ZDHHC13,SGCB,GM2A,COPS8,TDP1,HEMK1,CRNKL1,CCDC34,WDHD1,CCNF,VDAC1,C9orf40,PRDX1,KIF2A,MTHFD2,PSMD8,COX8A,DNAJC17,BAZ1B,ANP32E,RUVBL2,SMG9,SASS6,CDK2,FAF1 |
| 1.319e-05 | -11.24 | GSE14000_4H_VS_16H_LPS_DC_UP | MSigDB lists | GSE14000_4H_VS_16H_LPS_DC_UP | 173 | 48 | 17377 | 2626 |
DDX58,NDUFB6,DAP,CUTA,NDUFA4,NIPA2,ABHD14B,AP1B1,PIP5K1C,SRXN1,RPL23A,ASPHD2,ABL2,HOMER1,NDUFV1,ATP13A3,PTPN11,H2AFY,AHCY,TECR,LMAN1,RLIM,SRPK2,AMPD2,CYFIP1,SEPT9,BTG2,EMB,PARP4,ATXN1,ESYT1,DCLRE1C,METTL22,NDUFB1,SLC25A5,EIF3K,MKNK1,PON2,TMED10,CSK,DTX4,MEGF9,UQCRH,SPCS3,LTA4H,RTN3,ZC3HAV1,TMEM33 |
| 1.319e-05 | -11.24 | GSE18791_CTRL_VS_NEWCASTLE_VIRUS_DC_10H_UP | MSigDB lists | GSE18791_CTRL_VS_NEWCASTLE_VIRUS_DC_10H_UP | 173 | 48 | 17377 | 2626 |
NDUFA5,NAT9,CDC40,TP53RK,GXYLT1,MRPS2,URB2,GSPT2,CERK,GMCL1,IRF3,PLXNA1,BRIX1,EDC3,FLAD1,NFATC3,EXOSC7,SUV39H2,GATC,NOL11,DNAAF2,MSH2,GEMIN6,GPATCH1,PRADC1,TNRC18,ASB6,DDX28,ZNF559,GABPA,NUDT4,POLR2D,MRPL12,FRAT2,MTMR12,THNSL1,CDC23,IRF5,FBXO21,ZNF180,C1orf131,TATDN2,WNT5B,KBTBD7,PRMT7,COPS6,OSGEPL1,HRAS |
| 1.326e-05 | -11.23 | REACTOME_CLASS_I_MHC_MEDIATED_ANTIGEN_PROCESSING_PRESENTATION | MSigDB lists | REACTOME_CLASS_I_MHC_MEDIATED_ANTIGEN_PROCESSING_PRESENTATION | 232 | 60 | 17377 | 2626 |
UBE2D3,UBE2E2,TRIP12,SEC61G,UBR2,TRIM11,TAP1,CUL1,UBE2Z,UBE2Q1,UBE4A,PSMD9,ITGB5,HLA-A,FBXO3,PSMD2,PSMD1,CTSS,UBE2Q2,PSMA6,KLHL20,HUWE1,SEC24C,UBA5,TAP2,ANAPC7,UBE3B,UBE3C,LRSAM1,ASB6,UBE2M,SEC61B,PSMA8,RBX1,VHL,RNF25,CUL3,PSMB7,PSMA1,ANAPC2,CDC23,ASB13,PSMB9,PSMB3,PSMC4,SEC31A,HLA-B,KEAP1,CDC16,SEC61A1,CDC27,RPS27A,PSMD8,TPP2,PSMD3,TRIM32,UBE2C,SMURF1,PSMC1,ANAPC4 |
| 1.331e-05 | -11.23 | MORF_CCNI | MSigDB lists | MORF_CCNI | 86 | 29 | 17377 | 2626 |
MRPL9,RHOA,RPLP2,BAZ2A,WDR1,EIF3D,SUMO2,NACA,JTB,RNPS1,USP22,DAZAP2,EIF4G2,GNB2,EIF3H,CBX3,GNAS,RAB8A,NAP1L1,HINT1,DDOST,BRD2,RPS27A,H2AFY,YBX1,YWHAZ,BTF3,FAU,PCBP2 |
| 1.339e-05 | -11.22 | GSE37534_GW1929_VS_ROSIGLITAZONE_TREATED_CD4_TCELL_PPARG1_FOXP3_TRANSDUCED_DN | MSigDB lists | GSE37534_GW1929_VS_ROSIGLITAZONE_TREATED_CD4_TCELL_PPARG1_FOXP3_TRANSDUCED_DN | 154 | 44 | 17377 | 2626 |
MBD1,SLC12A7,PPP1R37,FEZ2,TMBIM4,GPBP1L1,WDYHV1,FAM53C,UROD,MYH9,GYG1,ELMOD2,STAM,CCDC28A,ATPAF1,PAIP2,MAT2B,PTPN2,GSTK1,DAD1,ATP13A3,RAB4A,CABLES2,EIF5,SCYL3,RNF169,PPP1R9B,FAM172A,PBXIP1,KAT7,PRKDC,ITM2A,FBXO9,TMEM41A,NEK1,PCM1,FBXO28,BRWD1,PIAS2,CNOT6,TCOF1,PTPDC1,CABLES1,NAA60 |
| 1.341e-05 | -11.22 | RNF126 (ring finger protein 126) | protein interactions | 55658 | 93 | 32 | 17029 | 2761 |
UBE2D3,PLK1,USP7,IMMT,COPA,KIAA0100,SCAMP3,RBX1,TRIM11,RRM1,MCM2,SLC25A5,EIF4G2,COPB2,EIF3A,XRCC5,EPRS,MDM2,SMC3,TRIM26,SNUPN,ATP2A2,QARS,E2F1,IARS2,MSH2,ASNA1,KLHL42,TRIM52,PFKP,MSH6,NUDT3 |
| 1.343e-05 | -11.22 | ZNF574 (zinc finger protein 574) | protein interactions | 64763 | 36 | 17 | 17029 | 2761 |
PPAN,TRIM41,NIFK,RPS2,SHCBP1,APP,RPSA,ANKRD28,LTBP4,MEX3C,RPS14,KBTBD7,UHRF2,H2AFX,PPP6R2,IFI16,ZC3HAV1 |
| 1.356e-05 | -11.21 | CREIGHTON_ENDOCRINE_THERAPY_RESISTANCE_1 | MSigDB lists | CREIGHTON_ENDOCRINE_THERAPY_RESISTANCE_1 | 479 | 107 | 17377 | 2626 |
SRM,ZBED3,ZBTB10,UBE2E2,ST13,ARID2,PTTG1,RBM8A,TPX2,RMI2,SLC29A1,C19orf48,PABPC4,ANKRD28,DST,DLG5,PA2G4,FBXL6,CD3EAP,DUT,UBA5,TNPO2,CDC25B,TOP1MT,MYBL1,ZNRD1,CPNE1,UBQLN4,RHOBTB3,NXT1,PPP1R18,CELSR2,HMGN4,BTG2,NLN,ATXN1,NUSAP1,AURKB,ESYT1,CADM1,ERC1,FKBP3,RPS9,RHBDF2,SUPT16H,C19orf54,MID1IP1,JAK1,MAP4,WDR4,LMBR1,OGT,DHTKD1,FKBP5,RRS1,POT1,PDCD4,TUBB,NADSYN1,GOLIM4,ANXA6,DHPS,CENPF,HAUS4,GTF3A,PMVK,METTL3,PIP4K2A,BZW2,HDDC2,GTPBP3,GSTK1,MEX3C,PTEN,ARPC5,HUWE1,ATIC,FUT8,ARHGEF2,RPL19,MDFIC,BCL2,FBL,LDLRAD3,TTLL12,LPCAT1,RPL22L1,MYO5A,GINS1,PPAN,ASPM,EMB,TEX10,ADSL,RFFL,PRMT2,XRCC5,SH3BP5,RBMX,SIAH2,HMGB2,DTD1,NR2F2,CDK2,CCNB2,UBE2C,GPATCH4 |
| 1.358e-05 | -11.21 | GCM_DFFA | MSigDB lists | GCM_DFFA | 117 | 36 | 17377 | 2626 |
RMND5A,RBM8A,BCL2L1,FAM8A1,REPS1,HEATR5B,RBM17,CSDE1,PA2G4,SMC3,MEX3C,BRPF3,CS,TARDBP,CHTOP,ARL5A,KDM3B,LARS,SNRNP200,BAZ2A,KAT7,ZNF512,CRNKL1,ARID1A,PRKRA,ARMC8,ZFAND5,CAND1,VEZF1,SCARB2,SMAD2,RBM25,HNRNPR,HNRNPH3,RBPJ,SLC25A33 |
| 1.359e-05 | -11.21 | GSE22935_UNSTIM_VS_12H_MBOVIS_BCG_STIM_MYD88_KO_MACROPHAGE_DN | MSigDB lists | GSE22935_UNSTIM_VS_12H_MBOVIS_BCG_STIM_MYD88_KO_MACROPHAGE_DN | 178 | 49 | 17377 | 2626 |
MUT,MUM1,CDT1,CHD1L,CENPF,STARD7,KIF23,C19orf48,HEATR5B,EEF2K,NUDT19,PRKD3,RINL,MEGF8,SSBP3,PIK3R2,RCSD1,CORO1A,GEMIN4,TTLL12,SLC35A1,TRIM14,PDLIM2,CARS2,ACSL5,ENPP4,GCC2,PTPN18,CDCA2,NFATC2,AURKB,PRKRA,RFC2,TRIM28,MAT2A,MAP3K4,MRPL2,WDR11,HAGHL,WDR7,OGT,C4orf46,TFDP2,CDK2,TMEM14A,TAF6,TUBB,SSSCA1,SVIP |
| 1.359e-05 | -11.21 | GSE13411_IGM_VS_SWITCHED_MEMORY_BCELL_DN | MSigDB lists | GSE13411_IGM_VS_SWITCHED_MEMORY_BCELL_DN | 178 | 49 | 17377 | 2626 |
TMEM106C,WSB2,ANKRD27,NDUFS1,MRPS2,CUL1,SECISBP2,RAB6A,MAPK14,CPNE3,SLC25A37,NDUFS4,WWP2,CLIC4,MLX,MBD2,RAB4A,KIF22,NFU1,STAT3,TNFAIP3,ZNF780B,GALC,ERLIN1,DNAJC9,EMP3,BCLAF1,AZI2,RHOT1,CYB5A,CAT,MAN2A2,MTMR3,TMEM127,HSPA4,SERTAD2,FNTA,PPP2R5A,WDR11,VCPIP1,PKD2,DDX5,HMGB2,WDR76,WDR91,CHPT1,RTN3,PURA,FAF1 |
| 1.365e-05 | -11.20 | MRPL47 (mitochondrial ribosomal protein L47) | protein interactions | 57129 | 69 | 26 | 17029 | 2761 |
NIFK,MRPL9,CYLD,MRPL42,MRPL39,MRPL12,MRPL43,RPL6,LAMTOR3,MRPL16,MRPL19,MRPL50,MRPL2,MRPL55,GRSF1,MRPL27,MRPL34,MRPL40,MRPL48,MRPL11,MRPL21,MRPL13,MRM3,MRPL3,MRPL32,MRPL57 |
| 1.365e-05 | -11.20 | CHCHD10 (coiled-coil-helix-coiled-coil-helix domain containing 10) | protein interactions | 400916 | 69 | 26 | 17029 | 2761 |
CMAS,PHF10,NDUFA5,COA3,IMMT,PRRC2A,ZFP91,MCCC1,STARD7,DHX8,SREK1,KLF13,CHCHD2,THRAP3,LUC7L,ECH1,STOML2,RBM23,FIZ1,SLC16A1,COX5A,CHTOP,PITRM1,FAF1,SLC25A1,TIMM50 |
| 1.375e-05 | -11.19 | sister chromatid cohesion | biological process | GO:0007062 | 121 | 37 | 17256 | 2622 |
MAPRE1,PHB2,DYNLL1,CENPF,CDCA8,NUF2,KIF2C,PMF1,SPDL1,MIS12,RB1,AHCTF1,SMC3,NUP107,NAA50,PDS5B,KIF22,CENPM,KNTC1,MCMBP,NUP85,SEH1L,NUDC,PLK1,TAOK1,RANGAP1,AURKB,CENPU,KIF2A,RAD51C,KIF18A,DSN1,BIRC5,CDCA5,CENPT,NDE1,DYNC1LI2 |
| 1.375e-05 | -11.19 | microtubule organizing center organization | biological process | GO:0031023 | 90 | 30 | 17256 | 2622 |
PLK1,GCC2,KIF3B,NDC1,PPP1R12A,TUBGCP5,HAUS4,CNTROB,BRCA1,KIF11,HAUS2,TUBGCP2,HAUS8,PCM1,CCP110,GOLGA2,CHD3,CENPJ,E2F4,ODF2,XRCC2,SLC16A1,NUP62,PKD2,CEP63,NDE1,WDR62,SASS6,CDK2,DCTN1 |
| 1.376e-05 | -11.19 | GDI1 (GDP dissociation inhibitor 1) | protein interactions | 2664 | 89 | 31 | 17029 | 2761 |
RAB14,UNK,UBQLN4,TK1,NDUFS1,RAB11B,RAB7A,INTS13,RAB6A,RAB1A,PSEN1,RAB5B,RAB11A,RAB22A,TRIM28,RAB2B,EPB41,RAB21,RAB8A,RAB18,EXOSC7,CDC42,RAB24,RAB35,RAB4A,TAGLN2,CDK2,GNAI2,HEXA,NMD3,ALDH9A1 |
| 1.376e-05 | -11.19 | TPR (translocated promoter region, nuclear basket protein) | protein interactions | 7175 | 89 | 31 | 17029 | 2761 |
SRSF11,SART1,STAU1,PRKDC,SUMO2,SF3B6,RPL6,CIRBP,BRCA1,SRSF5,MCM2,SDHA,RBM4,NUP205,LMNA,HNRNPA2B1,MAP3K4,MDM2,SHC1,EFTUD2,BUD31,NUP107,NUP153,RRS1,MAPK1,HRAS,DDB1,IFI16,ZC3HC1,EEF1D,CDC5L |
| 1.395e-05 | -11.18 | GSE3982_EOSINOPHIL_VS_TH2_DN | MSigDB lists | GSE3982_EOSINOPHIL_VS_TH2_DN | 183 | 50 | 17377 | 2626 |
CMAS,IMMT,DHPS,PTTG1,ZFYVE21,XPO7,NCAPG,NUP205,DDRGK1,EBP,PA2G4,CLIC4,SMC3,PSMA6,CCNA2,AHSA1,MRPS27,RBM3,MDFIC,NFU1,MINPP1,FBL,LMAN1,DNMT1,MTX2,LUC7L2,POU2AF1,CPNE1,PLK1,CCT2,SLC26A6,POLR2D,LDHA,NUSAP1,RANGAP1,TOMM40,CBFB,PDHX,OPTN,DNAJC10,KIF18B,BIRC5,LSM6,DCK,MDH1,LTA4H,PDLIM5,COIL,TERF1,TUBB |
| 1.395e-05 | -11.18 | GSE45365_NK_CELL_VS_BCELL_MCMV_INFECTION_DN | MSigDB lists | GSE45365_NK_CELL_VS_BCELL_MCMV_INFECTION_DN | 183 | 50 | 17377 | 2626 |
FGFR1OP,ZBTB10,CYLD,TXN,TRIP12,SCAMP3,ANXA6,SRGN,CDT1,TAP1,DHX9,ENSA,TIA1,TBC1D13,CHKB,MYO9B,TWF2,IL21R,PPP1R16B,RAB11A,GRSF1,TANK,TPST1,ARHGEF2,MVP,LPCAT1,CSNK1G3,SMC4,DCAF6,SEC61B,TNFAIP3,TMEM39A,HARS,MAP4K4,DNAJA1,PITPNB,RAB5B,STK17B,FAS,KIF2A,POLR2J,JAK1,SPATA2,GADD45B,MAP4,SMG9,NDE1,RUFY3,USP11,RPS6KC1 |
| 1.396e-05 | -11.18 | positive regulation of biosynthetic process | biological process | GO:0009891 | 1831 | 341 | 17256 | 2622 |
ZNF496,H2AFZ,CXXC1,HEXB,YTHDF3,CCNL2,EDRF1,PARK7,GLMP,CALM2,USF1,NOL11,DNM2,ECD,SENP1,CDC5L,KLF10,AATF,GABPA,AKT2,TOPORS,USP22,AURKB,CBFB,RFC2,ARF4,STOML2,DOT1L,MAP3K4,HHEX,MID1IP1,SMAD2,RPS27A,AXIN1,OGT,RNASEL,TFDP2,SMAD1,ARRB2,E2F2,NMD3,HDAC2,SVIP,DDX58,HIVEP3,HSPH1,CHTF18,PRKAA1,DHX9,EZH1,EIF2AK4,PSMD9,PARN,PSEN1,METTL3,CDC73,DDRGK1,TFAP4,FOXN2,MYDGF,PABPC1,NUP85,NSUN4,EIF5A,FOXK1,MTA2,MYBL2,BCLAF1,EXOSC9,ARID1A,ADRB2,ELK1,FXR1,KDM3A,MAP2K2,CCT8,XRCC5,SERTAD2,GOLGA2,ETS2,SETD3,RBMX,PIAS2,PPP3R1,CEBPG,YY1,MAP3K5,RNF14,CDK2,EGLN1,RHOG,KARS,TRERF1,IVNS1ABP,RPS6KA1,RAF1,EIF3D,MAGED1,RAC1,CREBL2,APP,CCNA2,SHC1,SP100,GMEB1,LPIN2,MRPS27,MAVS,RBM15,ATF2,RPRD1B,CDK12,CCT2,PSRC1,BRD4,RFC3,CDC123,KAT7,WBP2,POLR2D,CIRBP,E2F3,PFKFB3,EDF1,MEF2D,TAZ,SERP1,TRIM28,SUPT16H,DDX17,TAF2,VEZF1,SAFB,HIPK2,STAT1,TICAM1,ATF6,ATMIN,POU3F2,MECP2,TCF3,HABP4,ABHD14B,WDR5,BLM,ETS1,FOXO3,MAD2L2,WWP2,GTF2F1,CCNK,PRDM4,CARF,CITED2,CREB1,NCOA2,PPP3CA,KAT2A,NEK7,RFXANK,ILF3,ZP3,KLF6,PICALM,FADD,GPS2,PITX1,TFDP1,PML,DDX5,HMGB2,CD81,USF2,YWHAH,RORB,CCNC,ZBED3,ZNF76,IER2,HNRNPAB,THOC1,AGRN,AAMDC,NF1,KMT2E,GPBP1L1,FAM129A,SIRT2,MAPK14,CREM,TET3,PCNA,GLIS2,EIF4A3,ZNF639,ETV6,PIK3R2,MYBL1,MTPN,ARID4A,CARM1,ELOF1,RYBP,SP3,DEAF1,NCK1,VHL,MRPL12,UBE2V1,LRP5,BRCA1,EAF2,SOX4,USP21,UBTF,PAF1,E2F4,ZNF268,CHEK2,DVL1,CLU,POT1,PSMC1,ZNF564,PPP1R12A,CHCHD2,CTCF,MEF2A,CDK13,PPP3CB,THRAP3,RLF,ASXL2,CRLF3,ARID1B,SUB1,RB1,MLX,NFATC3,MED10,SSBP3,ZNF746,CTR9,ICE2,RBM3,YBX1,MDFIC,MAML1,ERLIN1,ACSL3,LDB1,GBA,UTP15,RTF1,EIF2A,NFATC2IP,IRF5,CAND1,RXRB,PSMC4,TBPL1,NLRC5,NUP62,ZFP90,RUVBL2,SMARCD1,TCF12,ASH1L,FOXM1,SMARCA4,PLAGL2,IRF3,PCBP1,PAIP1,HNRNPA2B1,RRN3,NRF1,NVL,PIN1,TARDBP,F2R,DVL2,CHP1,MOSPD1,POU2AF1,TIMP2,POLR2G,NFATC2,RPS9,RBL1,SCAP,STAT6,ARNTL,SCARB1,NCOA1,AKNA,MAPK1,SMAD4,NAT14,SLC30A9,BCL2L12,DNAJC2,EYA1,CDT1,AGO2,DBF4,KLF13,PAWR,NKRF,HMGN3,PAGR1,PTPN2,FASTKD3,IRF4,BRD7,ARHGEF2,SS18L1,PTGES3,STAT3,TGFB1,ELOVL5,COA3,DCAF6,RHOA,HMGN1,HMGN5,PRKDC,PRMT2,MEN1,MAPK3,TFEB,ATAD2,TFE3,E2F1,KMT2B,PKD2,RBPJ,NR2F2,ZMIZ1,HRAS,IFI16 |
| 1.399e-05 | -11.18 | Ktn1 (kinectin 1) | protein interactions | 16709 | 73 | 27 | 17029 | 2761 |
ELOVL5,KARS,LARS,RHOA,ERMP1,TRIP12,NOP2,ERLIN1,RPS24,VKORC1,BRIX1,RPL27A,LEMD2,PON2,DECR1,EPRS,DDOST,CDC42,IARS,ATP2A2,STT3A,TBL3,RRBP1,PTDSS1,IFI16,EEF1D,ESYT2 |
| 1.401e-05 | -11.18 | undifferentiated_carcinoma | COSMIC cancer mutations | undifferentiated_carcinoma | 1431 | 269 | 17385 | 2587 |
FGFR1OP,ZBTB10,MAX,TSC2,XIAP,USP39,MYEF2,FBXO22,EEF2K,NUP153,CDC25B,TFG,TIPARP,DNMT1,SENP1,USP34,BAK1,ERCC1,NRAS,AKT2,USP22,AURKB,CCNF,CBFB,TRIM47,WAS,SMAD2,RAD18,AXIN1,ITGB1,TRAF5,ARRB2,ZNF598,HDAC2,EWSR1,RHOC,PRKAA1,VAV2,RAB23,NOTCH2,APH1B,PSEN1,CDC73,MEX3C,ZNRF2,ATIC,MSH2,SOCS5,MFNG,USP10,RIT1,ARID1A,ADRB2,ELK1,RHOB,FAS,XRCC5,ETS2,ERGIC3,PIAS2,USP32,VCPIP1,NDE1,MAP3K5,CDK2,CABLES1,CDKN2A,ABCA3,ATXN3,DNMT3A,SF3B1,RAF1,SUZ12,RAC1,BCL2L1,PRKACA,KTN1,ANKIB1,REPS1,CCNA2,FBXL6,SHC1,KDM2A,RALB,UCHL5,ZCCHC2,SOCS6,CDKN1B,TTC3,RNASEH2A,RBM15,ATF2,CDK12,SHOC2,BRD4,ERF,ELP4,PKMYT1,MEF2D,ERC1,TRIM28,PPP2CA,RAD51C,PPP2R5A,JAK1,STAT1,FUS,EYA2,POLQ,RHEBL1,PRPF4B,USP13,OTUD5,TCF3,BRAP,BLM,IL21R,ETS1,FOXO3,MAD2L2,NEIL2,WWP2,RFWD3,CAPN2,PDCD10,PTEN,AXIN2,PTPN11,LTN1,UBE3B,CREB1,FBXL19,NCOA2,MSH6,PDPK1,TNFAIP3,KAT2A,KLF6,MARK2,PICALM,FADD,KEAP1,CCDC6,WNT5B,MAPK6,PML,PPP1R11,RGL1,PARP10,YWHAH,DDB1,NF1,TRIM11,CSNK2A1,S1PR2,USP48,MAPK14,BIRC2,FANCL,ABL2,RAP1A,CDC42,JAZF1,ETV6,XRCC2,PIK3R2,JOSD1,TCEA1,OGG1,CDC37,PLK1,SEPT9,CELSR2,APH1A,NCK1,VHL,LRP5,CDC6,BRCA1,USP21,RHEB,FBXO28,SOCS4,STK11,CHEK2,DVL1,COPS6,NUMB,PARP12,LAMTOR3,PCSK7,MEF2A,THRAP3,RAPGEF6,RB1,XPA,BCL2,ZRANB1,UBE3C,MAML1,CIC,KRAS,GNAS,SDHB,MBIP,TSC1,PCM1,PALB2,YWHAZ,NUP62,USP7,TCF12,PRKAB1,CYLD,TRAF7,PMS2,SMARCA4,EXT2,USP5,VAV1,MDM2,ABI1,DVL2,POU2AF1,BIRC3,SLC26A6,FANCE,USP36,EIF3H,STAT6,STK38,UHRF2,H3F3A,USP11,SMURF1,MAPK1,SMAD4,USP53,ABCA1,TRIP12,CASP6,CHIC2,CSNK1A1,FZD6,FBXO5,HERC3,KIF5B,IRF4,FGFR3,SS18L1,STAT3,TGFB1,HMGN1,RHOA,ADAM17,ARHGEF12,PCGF1,MEN1,MAPK3,TFEB,ATP6V1D,FBXO41,BIRC5,NEIL3,TFE3,DTX4,USP20,RBPJ,HRAS |
| 1.401e-05 | -11.18 | GO_PHOSPHATASE_BINDING | MSigDB lists | GO_PHOSPHATASE_BINDING | 159 | 45 | 17377 | 2626 |
PPP1R37,TSC2,STRN4,ENSA,PAWR,PPP3CB,MAPK14,LMNA,RPA2,SHC1,PPME1,PIK3R2,CDKN1B,CRY2,BCL2,ANAPC7,MAST2,MVP,STAT3,PPP6R1,CDC5L,ANKLE2,SHOC2,PPP1R9B,STAU1,PPP1R18,KAT2A,PPP1R21,KCNQ1,MAPK3,MASTL,AKAP1,CHCHD3,SMAD2,CDC27,JAK1,CSK,STAT6,CABIN1,PPP6R3,MAP3K5,IGBP1,MAPK1,ANAPC4,PARD3 |
| 1.401e-05 | -11.18 | RAP1A (RAP1A, member of RAS oncogene family) | protein interactions | 5906 | 85 | 30 | 17029 | 2761 |
UNK,TSC2,RAF1,RAB7A,ELOA,ILF3,TBRG4,SMARCA4,RAB1A,CDK11B,DUSP22,PRKACA,RAB5B,RAPGEF6,RHEB,FADD,KRIT1,FAS,AFDN,PON2,RAB8A,RAP1A,DNAJC8,HSPA4,CDC42,ARHGEF1,MRPL34,KIFAP3,HNRNPM,FAF1 |
| 1.401e-05 | -11.18 | KARS (lysyl-tRNA synthetase) | protein interactions | 3735 | 85 | 30 | 17029 | 2761 |
SNX8,LARS,CYLD,CUL1,KRAS,JMJD6,BRCA1,MCM2,CDC73,CCT8,RPSA,RPL36,CAND1,EPRS,MDM2,HSPA4,C1orf131,IARS,RPL17,PPME1,QARS,STAT1,TXLNA,RPL19,NAP1L4,GEMIN4,MAPK1,EEF1D,NUDC,SPTAN1 |
| 1.405e-05 | -11.17 | purine ribonucleotide metabolic process | biological process | GO:0009150 | 349 | 83 | 17256 | 2622 |
COX15,NDUFA5,PPCS,NDUFB6,UQCR10,OLA1,SLC35B2,EFL1,ADPGK,ATP6V1B2,ATP5PF,SDHA,IMPAD1,ADCY9,PPCDC,NDUFB9,SLC26A2,ADCY7,ATP6V0A1,OGDH,NDUFA7,NDUFB1,TAZ,STOML2,HINT1,GUCY1B1,NDUFA11,COX5A,DHTKD1,UQCRH,NUDT11,PFKP,NDUFV2,COX5B,GALK1,NDUFS1,MECP2,RAB23,NDUFA4,COX4I1,CYCS,ABHD14B,ATP5F1B,NDUFS7,NDUFS4,GART,NDUFV1,NDUFA2,NDUFB4,ATIC,MSH2,TPST1,ATP6V0A2,NDUFS8,CYC1,NDUFA3,AMPD2,TGFB1,RHOA,GUK1,NUDT4,LDHA,ADSL,ATP5MF,PKM,PDE3B,HSPA1B,ADSS,MBIP,ATP5MC3,PARG,PRPS2,COX7A2L,ACLY,COX8A,IMPDH1,ACAT1,NDUFS5,ATP5F1A,GPI,NIPSNAP2,PGAM1,NUDT3 |
| 1.415e-05 | -11.17 | AP2A2 (adaptor related protein complex 2 subunit alpha 2) | protein interactions | 161 | 77 | 28 | 17029 | 2761 |
GPBP1L1,EPN1,NUTF2,AP1B1,MCM2,KIF11,REPS1,APP,NECAP2,RPA1,PIP5K1C,UTP25,RPA2,ATP1A1,MEX3C,SHC1,MTMR4,AP1S1,GTSE1,AP2B1,YBX1,CLTB,PPP6R3,SMAD1,ARRB2,AP2S1,NUMB,TERF2 |
| 1.415e-05 | -11.17 | SNRPC (small nuclear ribonucleoprotein polypeptide C) | protein interactions | 6631 | 77 | 28 | 17029 | 2761 |
SARNP,EWSR1,AGGF1,SNRPB,MAGED1,ILF3,CUL3,HNRNPF,CUL1,PRPF3,NDUFA7,TOMM40,RBM4,SF3A2,MATR3,CAND1,WWP2,NDUFA2,GOLGA2,RBMS1,SS18L1,SNRPG,COPS6,SNRNP70,CD81,CARM1,DDX42,SRPK2 |
| 1.415e-05 | -11.17 | SRRT (serrate, RNA effector molecule) | protein interactions | 51593 | 81 | 29 | 17029 | 2761 |
COPS8,IMMT,EWSR1,PRKCSH,WDYHV1,VAV2,DHX9,CUL3,RNPS1,CSNK2A1,PCGF1,LUC7L,SF3A2,APP,TRIM28,POLR2A,MAGED2,CCNA2,CHD3,FBXO7,ACLY,PPP6C,TARDBP,GEMIN4,PPP6R3,STAT3,LUC7L2,HNRNPM,EEF1D |
| 1.415e-05 | -11.17 | MRPL39 (mitochondrial ribosomal protein L39) | protein interactions | 54148 | 81 | 29 | 17029 | 2761 |
MRPL9,CYLD,MRPL42,TCF3,MRPL12,MRPL43,ILF3,CUL3,LAMTOR3,NFATC2,MRPL16,ARMC8,MRPL19,CAND1,MRPL50,MRPL2,MRPL55,MRPL27,USP32,MRPL34,MRPL40,MRPL48,MRPL11,MRPL21,MRPL13,MRM3,MRPL3,MRPL32,MRPL57 |
| 1.417e-05 | -11.16 | Class I MHC mediated antigen processing & presentation | REACTOME pathways | R-HSA-983169 | 373 | 93 | 10287 | 1696 |
MIB2,KCTD7,TRIM41,UBE2E2,TRAF7,UBR2,TRIM11,TAP1,CUL1,UBE2Z,UBE2Q1,FBXO22,PSMD1,PSMA6,SIAH1,UBA5,FBXW2,ANAPC7,TAP2,RNF19A,ASB6,RLIM,SEC61B,PSMA8,RBX1,VHL,RNF25,PSMB7,CUL3,UBE2V1,CDC23,ASB13,CCNF,PSMB9,BTBD1,TRIM4,CDC16,SEC61A1,RPS27A,PSMD8,TPP2,PSMD3,TRIM32,KLHL42,FBXL3,SMURF1,PSMC1,UBE2D3,TRIP12,SEC61G,KLHL21,HLA-E,UBE4A,ITGB5,PSMD9,HLA-A,HERC3,PSMD2,UBE2Q2,CTSS,MEX3C,KLHL5,KLHL20,HUWE1,ZNRF2,SEC24C,FBXO7,LTN1,FBXL7,UBE3B,UBE3C,LRSAM1,FBXL19,UBE2M,PSMA1,FBXO9,ANAPC2,PSMB3,PSMC4,CTSL,SEC31A,HLA-B,FBXO21,FBXO41,KEAP1,CDC27,SNAP23,KBTBD7,SIAH2,RNF14,UBE2C,ANAPC4,RNF114 |
| 1.419e-05 | -11.16 | GO_SINGLE_ORGANISM_BIOSYNTHETIC_PROCESS | MSigDB lists | GO_SINGLE_ORGANISM_BIOSYNTHETIC_PROCESS | 1244 | 241 | 17377 | 2626 |
COX15,PIGM,PPCS,AGRN,MRPS15,PIGQ,HEXB,AGPAT1,DNAJC24,GLUD1,GYG1,NANS,CDIPT,OAT,MRPL19,PARK7,BCAT2,PCNA,GOT2,IMPAD1,PIK3R2,SLC44A1,PPCDC,MECR,AKR1B1,UPRT,SLC26A2,TECR,SPTSSA,MRPL32,ABCC5,PGAP2,DPM1,HARS,AKT2,MRPL12,MRPL43,RRM2,BRCA1,RFC2,PRPSAP1,ODC1,STOML2,ABHD5,ALG3,TRAM2,AGPAT2,RPS27A,MRPL27,QRSL1,MLYCD,ST3GAL2,MRPL13,CHPT1,CHPF2,POT1,SLC25A33,B4GALT2,SEPHS2,MRPL9,PIGN,MRPS2,DHPS,PRKAA1,SDC2,RRM1,B4GALT1,B4GALT4,NPLOC4,CHKA,DTL,NUS1,ATIC,BDH1,PIGG,ATP6V0A2,AHCY,PCYT2,MRPL48,MRPL40,ALDH18A1,MRPL21,PIKFYVE,LPCAT1,PHKG2,ALDH9A1,TERF2,FDFT1,EIF5A,PIGT,NOA1,AACS,NSDHL,PGS1,ACSL3,AMD1,RDH10,PIP4K2C,GBA,USP10,DCTD,MRPL16,THNSL1,KDM3A,MTR,ISG15,PI4K2A,ADSS,MTHFD2,DCK,PRPS2,TYW5,ACLY,LPCAT4,TBPL1,MDH1,SAMD8,SMPD4,GPI,ZNF830,NANP,HEXA,PDSS2,PTDSS1,MRPL3,GLT8D1,PRKAB1,MMACHC,KARS,TRERF1,SUCLG1,UGP2,MRPL39,MDH2,UROD,SLC2A1,UCK2,UCK1,CHKB,SLC35B2,LCLAT1,GGPS1,EXT2,CPNE3,EPM2A,TERF2IP,MRPL50,FLAD1,MTMR4,DUT,ADCY9,LPIN2,MRPS27,MRPL34,CYB5R1,TALDO1,GPD1L,TMEM14C,PDCL3,PRPF19,ADCY7,CPNE1,RFC3,CPOX,ATP6V0A1,MTMR6,SLBP,NDUFA7,TAZ,MRPS14,GAR1,PDHX,MAT2A,MRPL2,ALDH3B1,DAP3,MRPL55,CERS6,CHCHD1,MBOAT1,PDXK,SCARB1,B4GALT3,LTA4H,SLC25A39,MIF,NADSYN1,CDS2,MRPL42,B4GALT5,MRI1,TKT,MRPS26,SLC25A12,AGPAT3,ARF1,PMVK,GFM2,PIP4K2A,MAD2L2,PIP5K1C,EBP,MAT2B,RPA2,GSTK1,ERH,FGFR3,GART,GATC,COQ4,PTEN,FUT8,PTPN11,MRPL54,PTGES3,ST8SIA2,MRPL11,IMPA2,MYO5A,SLC25A1,GINS1,B3GALT6,TGFB1,AMPD2,CSNK1G2,ELOVL5,TK1,GUK1,POLK,TUFM,MRPS10,ADSL,PNPLA8,RPA1,MTMR3,UPF1,ACAT1,IMPDH1,ACADM,PGAM1,TERF1 |
| 1.420e-05 | -11.16 | rRNA processing | REACTOME pathways | R-HSA-72312 | 201 | 57 | 10287 | 1696 |
RPS15,DDX47,RPS2,NOP2,RPLP2,RPL15,RRP36,PNO1,RPL11,RPL23A,KRR1,UTP25,EXOSC7,NOL11,RPL17,UTP18,EXOSC1,RPL19,FBL,UTP4,MRM3,RPL22L1,NSUN4,MRM2,RPP25,RPL29,EXOSC6,RPL35,TEX10,WDR18,RPS10,RPL6,UTP15,RPL8,RPL38,RPS24,EXOSC9,BMS1,UTP3,RPL27A,GAR1,RPS9,RPSA,RPL36,UTP20,RPL37,RPL32,RPS27A,RPS14,TBL3,RPLP1,FAU,PDCD11,RPS26,CSNK1D,BYSL,DDX52 |
| 1.423e-05 | -11.16 | regulation of mitotic sister chromatid segregation | biological process | GO:0033047 | 65 | 24 | 17256 | 2622 |
PLK1,ZNF207,CDT1,CENPF,PTTG1,CUL3,CDC6,CCNB1,CDC23,BECN1,MAD2L2,RB1,CDC27,NEK6,NSMCE2,H2AFY,XRCC3,UBE2C,SLF1,GEN1,ESPL1,SLF2,ANAPC4,TACC3 |
| 1.424e-05 | -11.16 | CDKN1A (cyclin dependent kinase inhibitor 1A) | protein interactions | 1026 | 294 | 76 | 17029 | 2761 |
BCCIP,ATXN3,TXN,HMGXB3,MOGS,CUL1,CSNK2A1,SMARCA4,CCNB1,PRKACA,MAPK14,EXT2,GNB2,APP,CDK5,HNRNPA2B1,FLAD1,MDM2,PCNA,CCNA2,HADHB,CDKN1B,TAF5L,CDC5L,DEAF1,SNRNP200,RPL35,AKT2,CDC6,RAB1A,PDHX,RPS9,OPTN,GADD45B,ACTB,COPS6,USP11,SMAD4,TUBB,HDAC2,NCOR2,MCM10,RPS2,GADD45G,NKD2,BRAP,ATP5F1B,FOXO3,DTL,RB1,PSMD2,EFTUD2,MSH2,STAT3,PHKG2,TK1,PKM,MARK2,DAPK3,POLR2A,FBXO21,CDC27,QARS,PIAS2,E2F1,LRPPRC,KMT2B,DDX5,MAP3K5,RBBP4,CDK2,CCNB2,NRBP1,FAF1,DDB1,RNF114 |
| 1.426e-05 | -11.16 | GSE16451_CTRL_VS_WEST_EQUINE_ENC_VIRUS_IMMATURE_NEURON_CELL_LINE_DN | MSigDB lists | GSE16451_CTRL_VS_WEST_EQUINE_ENC_VIRUS_IMMATURE_NEURON_CELL_LINE_DN | 188 | 51 | 17377 | 2626 |
MCM10,GPR89A,TPX2,RACGAP1,NUF2,TCF19,NCAPG,FANCI,PSMD1,NEK6,IARS,COQ4,INTS7,DNAAF2,EI24,GEMIN6,MRPL48,CPSF4,GINS1,METTL1,PSRC1,LONRF3,MAPKAPK3,PBK,ZBED5,RRM2,CDC6,UHRF1BP1,SHCBP1,GAR1,GFER,ASF1B,GLOD4,IDE,HSPB11,ATAD2,POLE,DSN1,CDCA5,EIF2D,AEN,RBPJ,RUFY3,EHD4,TFDP2,ZMAT3,GCSH,IPO4,GPR89B,TIGD2,FAM72A |
| 1.426e-05 | -11.16 | GSE45365_NK_CELL_VS_BCELL_UP | MSigDB lists | GSE45365_NK_CELL_VS_BCELL_UP | 188 | 51 | 17377 | 2626 |
CTDP1,IER2,FAM208B,PPP1R15B,SLC2A1,CHIC2,AGFG1,RGS2,CRLF3,MYEF2,WRNIP1,ABL2,CAPN2,VASP,PCNA,MLX,ATP2A2,UTP18,IL6ST,FEM1B,METTL9,FBL,GCC1,SOCS5,RLIM,TTPAL,IFRD1,AGGF1,TNFAIP3,BIRC3,SIGMAR1,WDR1,NSUN2,SLBP,DNAJA1,DIDO1,ARL5B,PICALM,MAT2A,USP36,ARF4,UTP20,MID1IP1,MAPK6,SIAH2,YWHAZ,ATF6,MBOAT1,MAP3K5,ZC3HAV1,ESYT2 |
| 1.426e-05 | -11.16 | GSE22103_LPS_VS_GMCSF_AND_IFNG_STIM_NEUTROPHIL_UP | MSigDB lists | GSE22103_LPS_VS_GMCSF_AND_IFNG_STIM_NEUTROPHIL_UP | 188 | 51 | 17377 | 2626 |
POLA2,CYLD,SARNP,MRPL42,NDUFAF2,C1orf112,SLC41A1,MAGED1,MCCC1,STMN1,CPNE3,XPR1,ANKRD28,APLP2,GATC,NDUFB4,ETV6,PPP1R12C,AKR1B1,H2AFY,CDKN1B,ABCD1,GLTP,FAM76B,ATF2,CLN6,DNMT1,ARID4A,ELOVL5,TRAPPC9,NASP,NOA1,HELB,LDHA,NARF,CCDC34,WIPF1,UBE4B,VKORC1,RDH11,HAUS8,CHCHD3,MRPL55,CERS6,ZHX1,NSMCE2,BBX,ACLY,ACAT1,FAM126A,LRP8 |
| 1.426e-05 | -11.16 | GSE20198_IL12_VS_IFNA_TREATED_ACT_CD4_TCELL_UP | MSigDB lists | GSE20198_IL12_VS_IFNA_TREATED_ACT_CD4_TCELL_UP | 188 | 51 | 17377 | 2626 |
OTUD5,COX15,RWDD1,SESTD1,DAP,CHD1L,DHX9,ALKBH5,C5orf30,VTI1A,KLC1,UBE2Z,BLM,CSNK1A1,SLC20A1,CUTC,QSOX2,RNF103,KIAA1147,CENPJ,FUT8,NSFL1C,C8orf59,NUP85,POC5,GINS1,ACSL5,TXNL1,TDP1,TIMM8B,UBQLN4,FOXK1,TCTEX1D2,LYRM1,RABIF,EXOSC9,EIF2A,PPWD1,RIT1,GUF1,TTC33,ZFR,POLR2J,TMEM168,CDC27,CERS6,ACOX1,BCL7C,HIGD2A,CDKN2A,CWC25 |
| 1.426e-05 | -11.16 | GSE6674_CPG_VS_PL2_3_STIM_BCELL_DN | MSigDB lists | GSE6674_CPG_VS_PL2_3_STIM_BCELL_DN | 188 | 51 | 17377 | 2626 |
RWDD1,SUZ12,MRI1,GADD45G,AGPAT3,ATG2B,UBE2I,KIAA1147,WRNIP1,CSDE1,NRF1,VASP,EIF2S2,IARS,SAR1A,SEC24C,RAD23B,UBA5,TNPO2,NUP153,CYB5R1,ALDH18A1,EIF5,F2R,ABCC1,IFRD1,CLCN3,LARS,BRD4,FAM49B,ETV3,NET1,GOPC,TEX10,UHRF1BP1,AP4E1,PICALM,EIF3A,CAND1,NUCB1,EPRS,MTHFD2,GOLGA7,TAB2,TPP2,U2SURP,NFIL3,SIAH2,IMPDH1,ROCK1,DDX42 |
| 1.426e-05 | -11.16 | GSE17721_CTRL_VS_GARDIQUIMOD_24H_BMDC_DN | MSigDB lists | GSE17721_CTRL_VS_GARDIQUIMOD_24H_BMDC_DN | 188 | 51 | 17377 | 2626 |
TMED7,FAM208B,HNRNPAB,NQO1,THOC1,AGRN,MRPS2,GORASP1,UBR2,MDH2,SLC39A13,CHIC2,PXMP2,C14orf119,CSDE1,FKBP1A,PA2G4,RRN3,EIF2S2,CBWD2,CWC27,SSBP3,PTPN11,ANXA5,RP2,LRRC59,ABI1,CFL1,NUDC,MOB4,CCT2,ZNF672,USO1,TMEM39A,PSMB7,USP10,ARHGDIB,PRPF3,SEPT7,PSMB9,PSMC4,DNAJC10,HSPA4,NEK1,RAD18,SOCS4,RWDD4,PRMT7,NMD3,PFKP,ZNF146 |
| 1.426e-05 | -11.16 | GSE21360_PRIMARY_VS_QUATERNARY_MEMORY_CD8_TCELL_DN | MSigDB lists | GSE21360_PRIMARY_VS_QUATERNARY_MEMORY_CD8_TCELL_DN | 188 | 51 | 17377 | 2626 |
WASF2,CCDC93,UBL3,PPP1R12A,TSC22D3,LETMD1,ASAH1,TOP2B,TGOLN2,CLCC1,C2orf68,FAM192A,CAPN2,ADD3,SHC1,ZNF302,WDR44,ZBTB22,TTC17,CREB1,CITED2,ATF2,ABI1,CTDSP2,S100A6,TRIM14,VPS13B,SPTAN1,GCC2,CELSR2,BAZ2A,DCAF8,ZBED5,PTTG1IP,MACF1,ARMC8,ARHGAP15,RXRB,RPL37,VEZF1,ZNF862,PPP2R5A,TMED10,ARNTL,BBX,CTBS,CCDC69,PPP6R3,USP11,TRAF5,ZC3HAV1 |
| 1.426e-05 | -11.16 | GSE339_CD8POS_VS_CD4CD8DN_DC_IN_CULTURE_UP | MSigDB lists | GSE339_CD8POS_VS_CD4CD8DN_DC_IN_CULTURE_UP | 188 | 51 | 17377 | 2626 |
SLC12A7,PPIB,TXN,PRKCSH,SEC61G,TRIO,MOGS,LAMTOR3,AGPAT3,INO80E,RAB11A,REEP5,CMTM6,CDK5,DTL,FKBP1A,MDM2,SHC1,NEK6,RALB,RRBP1,PPP1R12C,H2AFY,FBXW2,ANXA5,MRPL21,PABPC1,LDHB,KAT2A,TSTA3,GALC,MAN1B1,RFXANK,RRM2,GALK2,UTP3,CADM1,OGFR,EDEM2,ODC1,PSMB9,PI4K2A,NUCB1,KEAP1,ACYP1,DTD1,PSAP,SCARB1,CD81,PFKP,NUMB |
| 1.429e-05 | -11.16 | ALCALA_APOPTOSIS | MSigDB lists | ALCALA_APOPTOSIS | 82 | 28 | 17377 | 2626 |
TMEM106C,HMGN1,TOMM20,RHOA,SCAMP3,COX4I1,RIT1,VDAC1,CYFIP2,APH1B,SYMPK,MARK2,NUP205,HLA-A,BCAT2,FAS,GNAS,ATP1A1,RALB,MFAP1,TIMM17A,MSH2,GPI,TALDO1,CHMP7,RTN3,AAAS,PFKP |
| 1.431e-05 | -11.15 | phosphorylation | biological process | GO:0016310 | 1261 | 245 | 17256 | 2622 |
CCNC,COX15,FGFR1OP,NDUFB6,ADAM10,MAP3K7CL,NF1,UQCR10,HMGXB3,CSNK2A1,CUL1,CCNB1,ATP5PF,MAPK14,EEF2K,CDK5,ABL2,PSMD1,NEK6,CDC42,IMPAD1,PIK3R2,NDUFB9,FNIP2,MAST2,CDC25B,FGFR1OP2,SRPK2,CDC37,PLK1,PLK3,NRAS,RBX1,AKT2,PBK,TLK1,GMFB,UBE2V1,AURKB,PRKRA,STK17B,STOML2,MAP3K4,MKNK1,SMAD2,RPS27A,PSMD8,LIMK1,AXIN1,COX5A,CAB39,BAZ1B,DHTKD1,UQCRH,STK11,CHEK2,RNASEL,ROCK1,SMAD1,PSMC1,PFKP,SEPHS2,NDUFV2,COX5B,CLSPN,GMFG,TRIO,PRKAA1,CERK,LAMTOR3,MEF2A,NDUFA4,COX4I1,ADCK5,CYCS,CDK13,EIF2AK4,PPP3CB,PSMD9,NDUFS7,CHKA,NDUFS4,PPP4R1,MSH2,DAPK1,BCL2,MDFIC,CYC1,PIKFYVE,MAML1,ALDH18A1,N4BP2,PHKG2,CSNK1G3,MORC3,COQ8A,MAPKAPK3,PIP4K2C,PSMA1,KRAS,EIF2AK1,MAP4K3,EIF2A,PKM,MAP2K2,DAPK3,PSMB3,PSMC4,PI4K2A,MASTL,CSK,CSNK1G1,DCK,PRPS2,COX7A2L,FN3KRP,GPI,ATP5F1A,MAP3K5,NIPSNAP2,CDK2,NRBP1,PRKAB1,NDUFA5,KARS,TP53RK,RPS6KA1,RAF1,RAC1,UCK2,ZFYVE21,UCK1,CHKB,ADPGK,PRKACA,LYN,CPNE3,SDHA,APP,CRKL,VAV1,PDK2,PRKD3,CCNA2,PSMA6,SHC1,ABI1,CDK12,SCYL3,CFL1,ULK3,PSMA8,TAOK1,MAP4K4,PSMB7,CUL3,PFKFB3,GALK2,OGDH,NDUFA7,PKMYT1,NDUFB1,TAZ,PSMB9,TOLLIP,ERC1,TRIM28,JAK1,TAB2,CLK3,FASTK,PSMD3,HIPK2,STK38,NDUFA11,PDXK,PPP5C,MAPK1,CSNK1D,PRPF4B,GALK1,NDUFS1,SH2D3A,MECP2,SCYL1,GNE,CCM2,BRAP,IP6K2,ATP5F1B,CDK11B,CSNK1A1,PMVK,SCYL2,PIP4K2A,PIP5K1C,CCNK,FASTKD3,FGFR3,PSMD2,NDUFV1,NDUFA2,GRK2,NDUFB4,PTPN11,NDUFS8,MAP3K14,CREB1,STAT3,GTF2H2,NDUFA3,CAMK2G,IMPA2,SPTAN1,PDPK1,TGFB1,CSNK1G2,TK1,GUK1,NEK7,PRKDC,LDHA,ILF3,PRKAR1B,NADK2,TBRG4,MEN1,ATP5MF,MARK2,CDK11A,MAPK3,NEK1,BIRC5,GPS2,ATP5MC3,MAPK6,COX8A,PML,KBTBD7,FAM126A,NDUFS5,RPS6KC1,PGAM1,HRAS,HIPK3 |
| 1.435e-05 | -11.15 | PNN (pinin, desmosome associated protein) | protein interactions | 5411 | 110 | 36 | 17029 | 2761 |
WSB2,COX15,CDC40,SARNP,PNISR,XAB2,DHX8,CSNK2A1,THRAP3,PIP4K2A,PARK7,EIF4A3,PPIG,SRSF4,AQR,LUC7L2,SRSF10,SRPK2,CDC5L,FYTTD1,ZMYND11,PPIE,RNPS1,CRNKL1,RPL6,SREK1,BCLAF1,TOPORS,LUC7L,SF3A2,CLK3,CFAP20,CDK2,NKAPD1,IFI16,PRPF4B |
| 1.445e-05 | -11.14 | STEIN_ESRRA_TARGETS_DN | MSigDB lists | STEIN_ESRRA_TARGETS_DN | 95 | 31 | 17377 | 2626 |
CSNK1G2,TRIM8,DCAF15,SIGMAR1,GNPDA1,TACC1,HLA-E,TRIO,UCK2,RFXANK,SEPT8,RABIF,DCTD,ATG2B,MXD4,CDC23,MBD4,TRAM2,FGFR3,NAP1L1,TNFAIP8,DBNDD1,TFE3,PRPS2,INTS12,NR2F2,ZNF45,ASB6,TERF1,ARID4A,MSH6 |
| 1.445e-05 | -11.14 | GSE5589_WT_VS_IL10_KO_LPS_STIM_MACROPHAGE_180MIN_UP | MSigDB lists | GSE5589_WT_VS_IL10_KO_LPS_STIM_MACROPHAGE_180MIN_UP | 145 | 42 | 17377 | 2626 |
C9orf78,H2AFZ,RWDD1,PDAP1,LAGE3,YTHDF3,PAWR,CHKB,ORC1,SLC20A1,TMEM161B,PIP4K2A,HDDC2,VAV1,PDCD10,CD3EAP,BDH1,FTSJ3,PLK3,TK1,PSMA8,ANKRD33B,GTPBP4,ITM2A,ARHGDIB,AP4E1,FOXRED1,POLG2,ABCF1,MAT2A,XRCC5,RAD51C,ELMO1,PRDX3,HNRNPR,STAT1,COX8A,FBXL3,SNRNP70,MRPL3,SLC25A33,N4BP2L2 |
| 1.453e-05 | -11.14 | GSE360_DC_VS_MAC_L_DONOVANI_DN | MSigDB lists | GSE360_DC_VS_MAC_L_DONOVANI_DN | 193 | 52 | 17377 | 2626 |
PPP1R12A,TM9SF4,URB2,TSC22D3,RPS6KA1,SUMO2,CDK2AP2,LAGE3,DNAJB1,FKBP2,GGPS1,ITGB5,METTL3,BCAP31,MYL6B,HDDC2,RPL11,MBD4,PHC2,VAV1,MTMR4,MDFIC,FBL,CTDSP2,YTHDC1,PPIF,ERCC1,NASP,KLF10,MRS2,RPL6,LDHA,USP10,PDE3B,KDM3A,EIF3H,RDH11,SOCS7,SDHB,NAP1L1,STT3A,STK38,CTBS,DTX4,OGT,CLN3,USF2,TAF6,COIL,ZC3HAV1,NUMB,FUBP1 |
| 1.453e-05 | -11.14 | GSE36527_CD62L_HIGH_VS_CD62L_LOW_TREG_CD69_NEG_KLRG1_NEG_UP | MSigDB lists | GSE36527_CD62L_HIGH_VS_CD62L_LOW_TREG_CD69_NEG_KLRG1_NEG_UP | 193 | 52 | 17377 | 2626 |
OTUD5,PARP12,KIAA0100,HLA-E,SLC41A1,B4GALT5,TOR3A,TAP1,C5orf30,ARF1,NCKAP1,CCNL2,UBE2I,CRLF3,CHD1,BIRC2,CMTM6,MXD1,CLIC4,ATP2A2,HUWE1,ZNF639,ARL6IP1,SUCLG2,NUP153,STRAP,USO1,TRAFD1,DDX24,RAD51AP1,NUDT4,RPL6,WIPF1,RFFL,TOR1AIP2,FAM133B,FXR1,ASB13,CHCHD6,ISG15,USP36,ANKRD46,FAS,PI4K2A,TRIM26,GOLGA7,STAT1,PML,CHMP4B,YWHAZ,RBPJ,RNF114 |
| 1.454e-05 | -11.14 | Parkinson's disease | KEGG pathways | hsa05012 | 129 | 40 | 7161 | 1149 |
NDUFA5,COX5B,NDUFV2,NDUFS1,NDUFB6,UQCR10,COX4I1,NDUFA4,CYCS,ATP5F1B,ATP5PF,PRKACA,SDHA,PARK7,NDUFS7,NDUFS4,NDUFV1,NDUFA2,NDUFB4,NDUFS8,NDUFB9,CYC1,NDUFA3,GNAI2,HTRA2,PPIF,VDAC2,NDUFA7,NDUFB1,VDAC1,SLC25A5,SDHB,ATP5MC3,NDUFA11,COX7A2L,COX8A,COX5A,UQCRH,NDUFS5,ATP5F1A |
| 1.458e-05 | -11.14 | FAELT_B_CLL_WITH_VH3_21_UP | MSigDB lists | FAELT_B_CLL_WITH_VH3_21_UP | 42 | 18 | 17377 | 2626 |
TK1,PRRC2A,PRKCSH,MYO9B,PKMYT1,TOMM40,VDAC1,CNOT3,UBTF,GNA12,E2F4,SAFB,ARHGEF1,PTPN7,DVL1,PPP5C,KCNAB2,SMARCD1 |
| 1.458e-05 | -11.14 | MODULE_158 | MSigDB lists | MODULE_158 | 42 | 18 | 17377 | 2626 |
RFC3,PRIM2,CENPF,RRM1,RRM2,ORC1,BLM,RFC2,CHAF1A,RPA1,PRIM1,NAP1L1,PCNA,POLE,HMGB2,RNASEH2A,RBBP4,CDK2 |
| 1.458e-05 | -11.14 | GCM_RAF1 | MSigDB lists | GCM_RAF1 | 42 | 18 | 17377 | 2626 |
UBE2D3,USP7,HMGN1,DHPS,DRAP1,RAF1,DDX39A,PCBP1,TRIM28,PCM1,GPS2,SRSF4,DDX5,PTGES3,H3F3A,PABPC1,CFL1,PCBP2 |
| 1.458e-05 | -11.14 | GO_PHOSPHATASE_COMPLEX | MSigDB lists | GO_PHOSPHATASE_COMPLEX | 42 | 18 | 17377 | 2626 |
SHOC2,PPP1R9B,PPP3CA,PPP1R12A,PPP1R2,NCK1,PPP1R15B,STRN4,WDR82,CYCS,PPP3CB,PPP1R3B,PPP2CA,PPP2R5A,PPP4R1,PPP3R1,PPP1R11,PPP2R2D |
| 1.459e-05 | -11.14 | GSE23321_CD8_STEM_CELL_MEMORY_VS_CENTRAL_MEMORY_CD8_TCELL_DN | MSigDB lists | GSE23321_CD8_STEM_CELL_MEMORY_VS_CENTRAL_MEMORY_CD8_TCELL_DN | 164 | 46 | 17377 | 2626 |
COX15,PKP4,TRIM11,MAGED1,TMX3,LETMD1,GTF3A,ABHD14B,PCBP1,SAC3D1,EBP,NUP210,SHC1,ZNRF2,PHTF1,ZDHHC13,CISD2,GLE1,MARCH2,MYBL1,MED22,ATP6V1G1,SRPK2,PHF20L1,AKT2,GOPC,KAT7,MFNG,SMC2,POLG2,SLTM,RAB2B,FAS,MAGED2,TSC1,TMED10,RBL1,CSK,PML,OSGEPL1,PLOD3,NDE1,PARP10,FAM208A,NAA60,PTOV1 |
| 1.469e-05 | -11.13 | CEP44 (centrosomal protein 44) | protein interactions | 80817 | 136 | 42 | 17029 | 2761 |
NOP9,TRIM41,FGFR1OP,TM9SF4,GGA1,POC1A,DCTN2,KLC1,CHIC2,FOXO3,QSOX2,SPAG5,ANKRD28,TXLNA,PPP6C,GPATCH1,CORO1A,CEP63,TP53BP2,ECD,RBM15,PPP6R1,DVL2,DCTN1,MOB4,CAMSAP1,DNAJA1,CDC23,SPPL2B,PLEKHF2,DHX57,HAUS8,CCZ1B,PSMD3,ODF2,EXOC4,MRFAP1L1,DVL1,PPP6R3,WDR62,ZNF598,BYSL |
| 1.471e-05 | -11.13 | UGP2 (UDP-glucose pyrophosphorylase 2) | protein interactions | 7360 | 54 | 22 | 17029 | 2761 |
UNK,HSPH1,UGP2,DCAF15,CUL1,NUSAP1,MCM2,GLRX3,LYN,PCBP1,TARS,ISG15,PAPOLA,CSDE1,GART,HDAC7,PPM1G,CDK2,ABCA1,FAF1,CARM1,NUDC |
| 1.487e-05 | -11.12 | RBD_domain_sf | interpro domains | IPR035979 | 245 | 62 | 18492 | 2768 |
NIFK,EWSR1,HNRNPAB,SRSF6,RBM8A,TIA1,BRAP,SAFB2,PARN,SRRT,MYEF2,RBM4,PABPC4,RAVER2,HNRNPA2B1,RBM17,RBM23,RBM34,GRSF1,SRSF4,TRA2B,TARDBP,RBM3,RBM12B,RBM15,PABPC1,HNRNPM,SRSF10,RBM15B,SRSF11,RBM42,PSPC1,NOL8,SF3B6,PPIE,HNRNPF,RNPS1,CIRBP,SREK1,SRSF5,EIF4H,EIF3G,SLTM,MATR3,SNRPA,RBM38,SRSF1,RBM25,RBM47,SYNCRIP,HNRNPR,HNRNPH3,SAFB,RBMX,U2SURP,DNAJC17,RBMS1,SRSF3,FUS,SNRNP70,HNRNPDL,CPEB2 |
| 1.498e-05 | -11.11 | Endocytosis | KEGG pathways | hsa04144 | 260 | 68 | 7161 | 1149 |
CHMP2A,PDCD6IP,RAB11B,RUFY1,GIT2,STAM,RAB8A,MDM2,ASAP2,CDC42,RAB35,RAB4A,DNM2,ZFYVE27,AP2B1,CLTB,F2R,RAB7A,WIPF1,CHMP2B,RAB5B,RAB22A,SMAD2,WAS,CHMP4A,VPS26B,SH3GLB2,CHMP4B,VPS4A,SMURF1,ARRB2,AP2S1,PARD3,SMAP1,HLA-E,ACAP1,VPS45,EPN1,ARF1,VPS25,RAB11A,HLA-A,TFRC,PIP5K1C,KIF5B,FGFR3,GRK2,ARPC5,ARF5,CAPZA1,TGFB1,CYTH1,RHOA,SNX2,ADRB2,CAPZA2,ARPC1A,SH3GLB1,SMAP2,HSPA1B,HLA-B,HGS,PML,ARAP1,EHD4,CHMP7,HRAS,VPS29 |
| 1.498e-05 | -11.11 | Endocytosis | KEGG pathways | ko04144 | 260 | 68 | 7161 | 1149 |
CHMP2A,PDCD6IP,RAB11B,RUFY1,GIT2,STAM,RAB8A,MDM2,ASAP2,CDC42,RAB35,RAB4A,DNM2,ZFYVE27,AP2B1,CLTB,F2R,RAB7A,WIPF1,CHMP2B,RAB5B,RAB22A,SMAD2,WAS,CHMP4A,VPS26B,SH3GLB2,CHMP4B,VPS4A,SMURF1,ARRB2,AP2S1,PARD3,SMAP1,HLA-E,ACAP1,VPS45,EPN1,ARF1,VPS25,RAB11A,HLA-A,TFRC,PIP5K1C,KIF5B,FGFR3,GRK2,ARPC5,ARF5,CAPZA1,TGFB1,CYTH1,RHOA,SNX2,ADRB2,CAPZA2,ARPC1A,SH3GLB1,SMAP2,HSPA1B,HLA-B,HGS,PML,ARAP1,EHD4,CHMP7,HRAS,VPS29 |
| 1.502e-05 | -11.11 | S Phase | REACTOME pathways | R-HSA-69242 | 130 | 41 | 10287 | 1696 |
POLA2,MAX,CDT1,CUL1,ORC1,PSMD9,RPA2,RB1,PSMD2,PCNA,PSMD1,SMC3,PSMA6,CCNA2,MCM5,PDS5B,CDKN1B,CDC25B,ORC3,GINS1,RFC3,PRIM2,PSMA8,PSMB7,PSMA1,CDC6,MCM2,PSMB9,RFC2,PSMB3,GINS4,PRIM1,RPA1,PSMC4,POLE,RPS27A,PSMD8,PSMD3,CDCA5,CDK2,PSMC1 |
| 1.505e-05 | -11.10 | WATANABE_RECTAL_CANCER_RADIOTHERAPY_RESPONSIVE_UP | MSigDB lists | WATANABE_RECTAL_CANCER_RADIOTHERAPY_RESPONSIVE_UP | 104 | 33 | 17377 | 2626 |
IVNS1ABP,POLR2K,RRM1,LAGE3,BTN3A1,PDXDC1,MFSD10,TERF2IP,RAP1A,AHCYL1,GNAI2,IMPA2,NUDC,TMEM115,HMGN4,WDR1,LYRM1,RPL38,MRPL12,USP10,SREK1,UBE4B,ARF4,DHX15,XRCC5,GOLGA4,ATP1A1,PPP2R5A,DUSP3,CTSA,MRFAP1L1,DDB1,CSNK1D |
| 1.511e-05 | -11.10 | GSE29617_CTRL_VS_DAY7_TIV_FLU_VACCINE_PBMC_2008_DN | MSigDB lists | GSE29617_CTRL_VS_DAY7_TIV_FLU_VACCINE_PBMC_2008_DN | 169 | 47 | 17377 | 2626 |
KIF3B,PPIB,NSMCE4A,UQCR10,MRI1,MAGED1,BABAM1,SDF2L1,FKBP2,BLM,METTL3,TTF1,MAN1A1,FAM192A,OIP5,FLAD1,HOMER1,IARS,NDUFB4,ZKSCAN1,NVL,NT5DC1,SLC44A1,RPAP1,SLC26A2,OSTC,ALDH18A1,PDIA6,PREB,POU2AF1,SEC61B,PPP1R21,METTL5,RRM2,EAF2,MEN1,AP4E1,MARK2,ECH1,PRDX1,DDOST,SEC61A1,STT3A,QRSL1,NAA20,PDCD11,DDB1 |
| 1.512e-05 | -11.10 | IL7R (interleukin 7 receptor) | protein interactions | 3575 | 106 | 35 | 17029 | 2761 |
HNRNPAB,SF3B1,HNRNPUL2,DHX9,RPL15,SNRPD3,LYN,PABPC4,YBX1,RBM3,STAT3,PABPC1,RPL29,SNRPB,RPL8,ILF3,CIRBP,RPL6,SNRPA,RPSA,JAK1,SYNCRIP,HNRNPR,HNRNPH3,RBMX,SAFB,MAP4,DDX5,SRSF3,SNRPG,FUS,SNRNP70,FAU,HNRNPDL,PURA |
| 1.512e-05 | -11.10 | HCFC1 (host cell factor C1) | protein interactions | 3054 | 106 | 35 | 17029 | 2761 |
MPHOSPH8,KMT2E,CXXC1,WDR5,HCFC1R1,ASXL2,LMNA,RPA2,USF1,ZNF335,FOXN2,PDCD2,EEF1D,FOXK1,GABPA,SNRPB,CUL3,E2F3,WDR82,BRCA1,MEN1,FOXRED1,TRIM28,ASF1B,RPA1,HSPA4,POLR2J,E2F4,OGT,E2F1,RBBP4,YY1,CDK2,USP53,HDAC2 |
| 1.522e-05 | -11.09 | HELICASE_ATP_BIND_1 | prosite domains | PS51192 | 108 | 32 | 12060 | 1670 |
DDX58,RECQL,DDX47,SHPRH,CHD1L,YTHDC2,DHX9,SMARCA4,DHX8,BLM,CHD1,DDX56,EIF4A3,DDX31,DDX28,SNRNP200,DDX24,DHX29,BTAF1,DDX20,DDX39A,DHX15,DHX57,RAD54B,DDX17,DDX23,CHD3,DHX16,DDX5,DDX42,POLQ,DDX52 |
| 1.522e-05 | -11.09 | HELICASE_CTER | prosite domains | PS51194 | 108 | 32 | 12060 | 1670 |
DDX58,RECQL,DDX47,SHPRH,YTHDC2,CHD1L,DHX9,SMARCA4,DHX8,BLM,CHD1,DDX56,EIF4A3,DDX31,DDX28,SNRNP200,DDX24,DHX29,BTAF1,DDX20,DDX39A,DHX57,DHX15,DDX17,DDX23,RAD54B,DHX16,CHD3,DDX5,DDX42,POLQ,DDX52 |
| 1.522e-05 | -11.09 | MODULE_159 | MSigDB lists | MODULE_159 | 78 | 27 | 17377 | 2626 |
EIF5A,RAB14,KARS,RHOA,EIF3D,TUFM,ARFIP2,RIT1,SEPT7,RAB1A,EIF4H,EIF4G2,RAB11A,ABCF1,EIF3G,ARF4,EIF3H,GNAS,GNA12,EIF2S2,CDC42,EIF4A3,RALB,ARF5,EIF5,GNAI2,EEF1D |
| 1.526e-05 | -11.09 | GO_REGULATION_OF_GENE_EXPRESSION_EPIGENETIC | MSigDB lists | GO_REGULATION_OF_GENE_EXPRESSION_EPIGENETIC | 218 | 57 | 17377 | 2626 |
MBD1,DNMT3A,H2AFZ,POLR2K,UBR2,SF3B1,SUZ12,MECP2,CTCF,SIRT2,METTL3,ARID1B,RBM4,SRRT,HNRNPA2B1,CD3EAP,MTA1,MBD2,ZNF335,H2AFY,POLR1B,TNRC18,ZNRD1,STAT3,DNMT1,ARID4A,RLIM,POLR2L,KAT2A,BAZ2A,WBP2,BRCA1,ARID1A,KCNQ1,PRKRA,KDM1B,MBD3,H2AFV,SLC50A1,TWISTNB,DOT1L,UPF1,SMAD2,ATAD2,DGCR8,H2AFX,BAZ1B,PRMT7,CNOT6,ACTB,BEND3,H3F3A,SMAD1,RBBP4,IFI16,HDAC2,SMARCD1 |
| 1.535e-05 | -11.08 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay | biological process | GO:0000184 | 117 | 36 | 17256 | 2622 |
RPS15,RPS2,RPLP2,GSPT2,RBM8A,RPL15,PARN,RPL23A,RPL11,RPL17,EIF4A3,DCP1A,RPL19,UPF2,PABPC1,RPL29,RPL35,RPL6,RNPS1,RPL8,RPL38,RPS10,RPS24,RPL27A,RPS9,RPSA,RPL36,PPP2CA,RPL37,UPF1,RPL32,RPS27A,RPS14,RPLP1,SMG9,RPS26 |
| 1.551e-05 | -11.07 | RAD23A (RAD23 homolog A, nucleotide excision repair protein) | protein interactions | 5886 | 154 | 46 | 17029 | 2761 |
ATXN3,EWSR1,GNPDA1,VAV2,PTTG1,UBQLN2,PSEN1,USP5,RAD23A,RPN1,PSMD2,MDM2,PCNA,PSMD1,PSMA6,CCNA2,HUWE1,UCHL5,RAD23B,TACC3,MORC3,CDC37,TXNL1,GCC2,UBQLN4,PSMB7,PSMA1,UBE4B,MPG,ERC1,PSMB3,CLNS1A,PRDX1,PSMC4,XRCC5,PI4K2A,PSMD8,PSMD3,DBI,HEXA,TRAF5,SMURF1,NGLY1,PSMC1,FAF1,USP13 |
| 1.551e-05 | -11.07 | SPICE1 (spindle and centriole associated protein 1) | protein interactions | 152185 | 154 | 46 | 17029 | 2761 |
FGFR1OP,SKA3,LUZP1,TOP2B,SECISBP2,HAUS4,CCNB1,ARID1B,HAUS2,SPAG5,MCTS1,PA2G4,CENPJ,RAB35,KIF14,BANF1,GTSE1,TRA2B,RPF2,CEP63,NAP1L4,RBM15,MTPN,SRP72,HMGN1,CCDC138,CAMSAP1,C1orf35,CKAP2L,MAP7D1,EML4,ECH1,SUPT16H,HAUS8,NSA2,KIF2A,NAP1L1,PCM1,GOLGA2,RBMX,CEP55,GPI,BTF3,ECPAS,IPO4,SSRP1 |
| 1.558e-05 | -11.07 | HIV Life Cycle | REACTOME pathways | R-HSA-162587 | 152 | 46 | 10287 | 1696 |
CTDP1,CHMP2A,NDC1,PDCD6IP,NUP188,POLR2K,RAE1,NUP54,NUP205,GTF2F1,CCNK,NUP210,BANF1,NUP107,NUP153,TCEA1,GTF2H2,NUP85,SEH1L,POLR2I,POLR2L,POLR2G,ELOA,POLR2D,NUP155,RANGAP1,CHMP2B,POLR2A,NMT2,XRCC5,SUPT16H,TAF2,KPNA1,CHMP4A,POLR2J,RPS27A,NUP62,CHMP4B,TAF12,VPS4A,CHMP7,XRCC4,TAF6,NUP58,AAAS,SSRP1 |
| 1.559e-05 | -11.07 | GSE40666_STAT1_KO_VS_STAT4_KO_CD8_TCELL_WITH_IFNA_STIM_90MIN_UP | MSigDB lists | GSE40666_STAT1_KO_VS_STAT4_KO_CD8_TCELL_WITH_IFNA_STIM_90MIN_UP | 174 | 48 | 17377 | 2626 |
EXOC3,COX5B,NADSYN1,GLT8D1,ZFP91,HNRNPUL2,UCK1,AKT1S1,INTS7,LRRC8D,MCM5,EFTUD2,CDKN1B,GLTP,ZNF226,CYC1,NAP1L4,AQR,TALDO1,MVP,TACC3,CYTH1,RBM42,ATG9A,RFXANK,TOP3A,PSMG1,RTF1,FAM50B,MEN1,RHOT2,FOXRED1,ZNF174,BBS12,EIF3H,XRCC5,DTWD1,ANKZF1,DGCR8,WDR59,ZNF436,PKD2,NCOA1,FAU,TFDP2,TERF1,SLC25A39,CCDC137 |
| 1.559e-05 | -11.07 | GSE21670_STAT3_KO_VS_WT_CD4_TCELL_TGFB_IL6_TREATED_UP | MSigDB lists | GSE21670_STAT3_KO_VS_WT_CD4_TCELL_TGFB_IL6_TREATED_UP | 174 | 48 | 17377 | 2626 |
SLC30A9,H2AFZ,MUT,ANXA6,UROD,RAC1,TKT,VTI1A,UCK1,GLUD1,TWF2,SNAPC4,PARK7,FBXO3,ADD3,DUS4L,ETV6,GPATCH1,TAGLN2,CENPM,CITED2,F2R,MCMBP,MTPN,PACS2,KCNAB2,CFL1,NIPSNAP1,AMPD2,PPP3CA,DDX28,ETV3,POLK,NSDHL,RABIF,EMP3,NLN,KRAS,GLO1,IL12RB1,AZI2,ABCF1,STOML2,CAT,H2AFX,NUP62,DTD1,BRD9 |
| 1.563e-05 | -11.07 | TMBIM4 (transmembrane BAX inhibitor motif containing 4) | protein interactions | 51643 | 10 | 8 | 17029 | 2761 |
PPIB,DDOST,SLC27A4,RPN2,COX4I1,MTX1,VKORC1,PRPSAP1 |
| 1.572e-05 | -11.06 | response to stress | biological process | GO:0006950 | 3367 | 591 | 17256 | 2622 |
RAB14,ADD1,XIAP,RBM4,FBXO22,PABPC4,EEF2K,CDK5,USF1,PSMD1,GSDMB,RAD23B,PDS5B,DNM2,FNIP2,CRY2,PCBP2,PLK3,BAK1,PGAP2,ERCC1,AATF,WDHD1,TOPORS,MCL1,ARF4,GINS4,PLEKHF2,STOML2,SMAD2,RAD18,RPS27A,AXIN1,PRDX5,MPV17,MLYCD,RNASEL,TFDP2,SMAD1,SSRP1,CLSPN,SEC61G,RHOC,MUM1,DHX9,RAB23,EIF2AK4,PSMD9,LMNA,DDRGK1,MCTS1,CD59,TFAP4,SMC3,INTS7,MYDGF,IFRD1,ZMYND11,MAN1B1,ERO1A,USP10,ARMT1,BCLAF1,MPG,ABCF1,MATR3,RHOB,PTPRF,SCARB2,PDLIM1,POLR2J,CSK,CNOT6,WIPI2,ZNF830,RNF139,ALS2,EGLN1,RHOG,NQO1,CHD1L,ACTR3,PTTG1,RMI2,MYH9,INO80E,PRKACA,APP,ATP2A2,SP100,MTA1,UBA5,NABP1,MAVS,CEP63,ATF2,RNF169,DCTN1,ENPP4,ULK3,SEC61B,POLR2L,KAT7,MAP4K4,CIRBP,POLR2D,DNAJA1,RAB1A,DDX17,ALDH3B1,SEC61A1,VPS26B,NSMCE2,HIPK2,TICAM1,PPP5C,GEN1,TUBB,USP13,CCM2,FLOT1,IP6K2,UBE4A,ETS1,NEXMIF,NEIL2,SRXN1,CAPN2,RPA2,PSMD2,PDCD10,SUV39H2,NDUFB4,HUWE1,ANXA5,GTSE1,GTF2H2,TMX1,PDPK1,STAU1,PPP3CA,TNFAIP3,POLK,LDHA,DDX39A,RPA1,POLE,GPS2,TATDN2,WNT5B,PML,AEN,LY75,HMGB2,WDR76,FAM129A,TRIM11,PPP1R15B,BIRC2,FANCI,PRNP,SSR1,FANCL,ABL2,PCNA,XRCC2,PIK3R2,MTPN,CDC37,PTPRK,PLK1,MIOS,RBX1,RAD51AP1,TLK1,UBE2V1,BRCA1,IL12RB1,PRKRA,OPTN,DPYSL3,TRIM4,TONSL,E2F4,ADAM9,ACTB,TMUB1,PHB2,DNAJB2,DNAJB1,DOCK11,CNOT11,ARID1B,TIGAR,XPA,TIMELESS,AHCY,MDFIC,PREB,ABHD2,AACS,KRAS,EIF2AK1,MAP4K3,UBE4B,IRF5,PSMC4,MBIP,PAXX,SYNCRIP,PALB2,SNAP23,NLRC5,RUVBL2,ECPAS,BCCIP,USP7,CYLD,FOXM1,XAB2,SUMO2,TMX4,SLC2A1,RRAGC,LYN,RPAIN,RAD23A,VAV1,PDK2,PSMA6,MDM2,ABRAXAS2,TARDBP,CORO1A,LMAN1,SPIDR,CTDSP2,PRPF19,PPIF,MND1,POLR2G,PSMA8,BTG2,PPIE,SLC26A6,NFATC2,DCLRE1C,DNAJC10,SCAP,MAFK,PSMD3,PLGRKT,XRCC3,H3F3A,CHID1,SMAD4,RAD51D,SLC30A9,MCM10,DAP,ARID5A,TMX3,SMC6,PAGR1,RMI1,FZD6,DNAJB9,WRNIP1,IRF4,CAMK2G,RNF5,RNLS,RHOA,CSRP1,PRKDC,TOP3A,RANGAP1,CHCHD6,NEK1,TRIM26,KPNA4,PDCD6,NEIL3,E2F1,PKD2,RBPJ,IFI16,MAX,TXN,CXXC1,TSC22D3,TMEM109,TAP1,CUL1,UBE2I,CCNB1,PARK7,ELMOD2,POLR3K,PARPBP,TRA2B,SEH1L,CDC5L,KLF10,MRNIP,RFC2,DOT1L,MAP3K4,HHEX,WAS,PSMD8,ITGB1,SLF1,ARRB2,ZMAT3,HDAC2,DDX58,RECQL,HSPH1,POLR2K,HLA-E,GADD45G,VAV2,PRKAA1,B4GALT1,CYCS,PXMP2,PSEN1,METTL3,NPLOC4,CNOT3,JMY,WDR48,CFLAR,RNF121,DAPK1,TPST1,MSH2,RNF135,ANKHD1,APOL1,TERF2,SOCS5,CPQ,CAPZA2,ADRB2,PKM,MAP2K2,MTR,PSMB3,XRCC5,FAS,AKAP1,CAT,SEC31A,DERL1,EPRS,CEBPG,MAP3K5,YY1,CDK2,ZC3HAV1,CDKN2A,DNMT3A,ATXN3,RWDD1,RAF1,RPS6KA1,RAC1,BCL2L1,MOAP1,TERF2IP,CRKL,CCNA2,KDM2A,SHC1,RALB,UCHL5,SOCS6,CDKN1B,AQR,RNASEH2A,GPX4,CDKN2AIP,BRD4,RFC3,TAOK1,CUL3,LRRC8A,PSMB9,POLG2,SERP1,TRIM28,SUPT16H,ANKZF1,VEZF1,RAD51C,HSPA4,JAK1,GUCY1B1,FAAP100,H2AFX,STAT1,SEL1L,ATF6,TRIM32,XRCC4,EYA2,ATMIN,POLQ,MECP2,BABAM1,SDF2L1,BLM,FOXO3,MAD2L2,HLA-A,RFWD3,RBM17,CCNK,PTEN,CENPJ,AHSA1,PTPN11,COPS7B,CNOT6L,CREB1,MAP3K14,CITED2,CNPY3,MSH6,NET1,ILF3,PARP4,ADSL,FBXO9,MACF1,SH3GLB1,FADD,POLR2A,PRDX1,YIF1A,GNA12,PRDX3,TFDP1,PPP1R11,ASNA1,CPEB2,DDB1,UBE2E2,NF1,ALKBH5,SLC29A1,SIRT2,UBQLN2,MAP1LC3B,MAPK14,BECN1,RNF103,MBD4,DST,CYREN,CDC42,RCSD1,AKR1B1,KIF22,TCEA1,OGG1,CARMIL1,TRIM14,CARM1,FGFR1OP2,SRPK2,COPS8,TDP1,DEAF1,LARS,TRIM8,NCK1,VHL,SOX4,CHAF1A,PQBP1,CAB39,CRCP,BAZ1B,STK11,CLU,CHEK2,COPS6,PSMC1,UBE2D3,NSMCE4A,TM9SF4,AGTRAP,UFC1,CIB1,CDIP1,EPHX2,PITHD1,RHBDD1,DTL,NFATC3,CAPZA1,BCL2,SLC12A2,ATP6V0D1,HP1BP3,ATP5IF1,POLR2I,ERLIN1,OXR1,GBA,PSMA1,EIF2A,SYVN1,VKORC1,ISG15,DAPK3,MASTL,GNAS,KLHL15,CDCA5,YWHAZ,APOL2,ADNP2,PMS2,IRF3,ANKLE1,BABAM2,AKAP8,PPP6C,F2R,PDIA6,FAM3A,HTRA2,CGAS,PSMB7,EDEM2,HERPUD2,TOLLIP,FANCE,RAD54B,PON2,TAB2,STAT6,HPS5,WDR59,ARNTL,GADD45B,SCARB1,MAPK1,SMURF1,ABCA1,TMEM33,MIF,GCLM,TRIP12,SH2D3A,SHPRH,EYA1,VPS45,MRPS26,FERMT3,KIF5B,TANK,NABP2,ARHGEF2,NDUFS8,ATG13,STAT3,TGFB1,TXNL1,HMGN1,ADAM17,HELB,PSPC1,PRKAR1B,RCOR1,MEN1,HSPA1B,MFN2,MAPK3,CNOT9,MTMR3,HLA-B,UPF1,PLAA,ACAT1,SLF2,HRAS |
| 1.586e-05 | -11.05 | YBX1 (Y-box binding protein 1) | protein interactions | 4904 | 209 | 58 | 17029 | 2761 |
UNK,RPS2,CYLD,EWSR1,HNRNPAB,IVNS1ABP,SUZ12,RPS6KA1,MECP2,HABP4,FLOT1,CUL1,CTCF,CSNK2A1,LMNA,RPL23A,SF3B2,HNRNPA2B1,PA2G4,PCNA,EIF4A3,MCM5,YBX1,LMAN1,MVP,PCBP2,SRPK2,SRP72,STAU1,SNRNP200,PRKDC,RPL6,SMU1,CUL3,SREK1,USP10,EXOSC9,BRCA1,SMC2,MATR3,FKBP3,SF3A2,RPSA,PSMC4,CAND1,EIF3K,SYNCRIP,H2AFX,COX5A,FUS,RRS1,ARRB2,MAPK1,SMURF1,PURA,ZC3HAV1,DYNC1LI2,TUBB |
| 1.588e-05 | -11.05 | HNRNPL (heterogeneous nuclear ribonucleoprotein L) | protein interactions | 3191 | 119 | 38 | 17029 | 2761 |
UNK,CYLD,IVNS1ABP,ACTR3,CUL1,CSNK2A1,NPLOC4,LMNA,HNRNPA2B1,RPA2,FGFR3,EIF4A3,NAA50,PCBP2,HNRNPM,ABCC1,VHL,CUL3,ILF3,TUFM,TOPORS,BRCA1,PLEC,MCM2,EIF4H,MATR3,DHX15,ISG15,DDX17,CAND1,RPA1,HSPBP1,SYNCRIP,HNRNPR,MPV17,YWHAZ,FUS,HNRNPDL |
| 1.593e-05 | -11.05 | SWI/SNF superfamily-type complex | cellular component | GO:0070603 | 71 | 25 | 18223 | 2701 |
PHF10,MTA2,SUZ12,CSNK2A1,SMARCA4,ARID1A,PBRM1,INO80E,MBD3,APPL1,ARID1B,YY1AP1,USF1,RB1,CHD3,UCHL5,APPL2,ANP32E,SS18L1,RUVBL2,YY1,RBBP4,SMARCE1,HDAC2,SMARCD1 |
| 1.599e-05 | -11.04 | AMIT_EGF_RESPONSE_480_HELA | MSigDB lists | AMIT_EGF_RESPONSE_480_HELA | 155 | 44 | 17377 | 2626 |
MBD1,AGRN,DHPS,XAB2,HMGXB3,RHOC,TRIO,DLGAP4,B4GALT1,MYO9B,BCL2L1,GLRX3,ITGB5,PNO1,SLC25A37,PHC2,VASP,MTA1,RRBP1,ARHGEF2,TMEM8A,PPIF,ERCC1,ABHD2,SEPT9,NET1,NUDT4,CAMSAP1,HEBP2,RANGAP1,FAM50B,PLEC,LY6E,PICALM,DAPK3,PTPRF,SLC19A1,BRD2,LPCAT4,H2AFX,NCLN,USF2,PDLIM5,EGLN1 |
| 1.601e-05 | -11.04 | GSE45739_NRAS_KO_VS_WT_UNSTIM_CD4_TCELL_UP | MSigDB lists | GSE45739_NRAS_KO_VS_WT_UNSTIM_CD4_TCELL_UP | 179 | 49 | 17377 | 2626 |
BCCIP,DDX47,FAM208B,MCM10,HJURP,KLHL21,NDUFAF2,MRPL39,SLC2A1,TMEM97,UCK2,NKD2,BCL2L1,POLR3K,JAKMIP1,FARSA,EIF2S2,UTP18,CD3EAP,MSH2,BCL2,NUDC,PLK3,DDX28,ANKRD37,LONRF3,MAPKAPK3,CDC123,TEX10,HNRNPF,MFNG,PFKFB3,CDC6,DNAJA1,UTP3,PITPNB,ICAM2,GAR1,DDX39A,KLF6,ALG3,ATAD2,TIMM17A,MAPK6,PITPNA,LRP8,NMD3,GPATCH4,IPO4 |
| 1.601e-05 | -11.04 | GSE36009_UNSTIM_VS_LPS_STIM_DC_DN | MSigDB lists | GSE36009_UNSTIM_VS_LPS_STIM_DC_DN | 179 | 49 | 17377 | 2626 |
HIVEP3,RHOG,PHRF1,ADO,FAM76A,CERK,DNAJB1,LYRM2,GIT2,PAIP2,SRXN1,C1GALT1,MEX3C,KLF16,ZNF639,METTL14,RCSD1,FOXN2,MAML1,CTDSP2,TMBIM1,ABCC1,ACP2,MTA2,PPP1R21,ZNF574,POLR2D,ATP6V0A1,RABIF,SLBP,MAP7D1,WDR81,TOLLIP,LUC7L,STK17B,TAF2,KPNA1,MID1IP1,SMAD2,FBXO28,DUSP3,TAB2,OGT,AKNA,ATP6V1C1,ZBTB11,TERF1,TOB1,PPP2R2D |
| 1.601e-05 | -11.04 | GSE3982_EOSINOPHIL_VS_BCELL_DN | MSigDB lists | GSE3982_EOSINOPHIL_VS_BCELL_DN | 179 | 49 | 17377 | 2626 |
TCF3,RRM1,CTCF,SMARCA4,RACGAP1,DUSP22,PARN,PMVK,RUFY1,REEP5,NUP205,MAT2B,CAPN2,IRF4,RRN3,CLIC4,ZNF473,UTP18,NVL,AKR1B1,SUCLG2,SLC38A10,FBL,DNMT1,HTRA2,ATP6V1G1,NIPSNAP1,JMJD4,ABCF2,USP10,GORASP2,MTX1,UTP3,NDUFA7,PRKRA,DHX57,STOML2,RPL37,DAP3,WDR11,COX7A2L,FAM3C,MPV17,BAZ1B,FN3KRP,KPNA2,KLHDC4,RRS1,IFI16 |
| 1.601e-05 | -11.04 | GSE17301_ACD3_ACD28_VS_ACD3_ACD28_AND_IFNA5_STIM_CD8_TCELL_UP | MSigDB lists | GSE17301_ACD3_ACD28_VS_ACD3_ACD28_AND_IFNA5_STIM_CD8_TCELL_UP | 179 | 49 | 17377 | 2626 |
HJURP,CLSPN,DEPDC1,FOXM1,TPX2,CDCA3,SLC29A1,KIF2C,AP1B1,SNAPC4,KIFC1,CDKN2C,CLIC4,GART,SLC1A4,PPME1,ETV6,DAPK1,GTSE1,MAST2,CENPM,LMAN1,MICAL3,CFL1,TK1,PRRC2A,ASPM,CIC,MYBL2,MKI67,SEPT8,RRM2,NUSAP1,PKMYT1,TOMM40,CCNF,RHOT2,SPPL2B,ASF1B,HMGN2,HSPBP1,FASTK,HMGB2,WDR62,CCNB2,ESPL1,AAAS,LRCH1,POLQ |
| 1.609e-05 | -11.04 | LIN_APC_TARGETS | MSigDB lists | LIN_APC_TARGETS | 74 | 26 | 17377 | 2626 |
EIF5A,TELO2,AGRN,PRRC2A,PRKCSH,PDAP1,ACAP1,ATP6V0A1,SLC35B2,LY6E,ETS1,BCAP31,POLR2A,LMNA,FBRS,ADSS,ALG3,GNA12,PCNA,SEC61A1,SCAP,MTA1,CPSF4,SNRNP70,CAPN1,ABCC1 |
| 1.611e-05 | -11.04 | Regulation of actin dynamics for phagocytic cup formation | REACTOME pathways | R-HSA-2029482 | 61 | 24 | 10287 | 1696 |
WASF2,CYFIP1,NCK1,ACTR3,VAV2,RAC1,MYH9,WIPF1,MYO9B,NCKAP1,CYFIP2,ARPC1A,MAPK3,VAV1,WAS,CDC42,ELMO1,ARPC5,LIMK1,ACTB,MAPK1,ABI1,MYO5A,CFL1 |
| 1.611e-05 | -11.04 | Major pathway of rRNA processing in the nucleolus and cytosol | REACTOME pathways | R-HSA-6791226 | 179 | 52 | 10287 | 1696 |
RPS15,DDX47,RPS2,RPLP2,RPL15,RRP36,PNO1,RPL11,RPL23A,KRR1,UTP25,EXOSC7,NOL11,RPL17,UTP18,EXOSC1,RPL19,FBL,UTP4,RPL22L1,RPP25,RPL29,EXOSC6,RPL35,TEX10,WDR18,RPS10,RPL6,UTP15,RPL8,RPL38,RPS24,EXOSC9,BMS1,UTP3,RPL27A,RPS9,RPSA,RPL36,RPL37,UTP20,RPL32,RPS27A,RPS14,TBL3,RPLP1,FAU,PDCD11,RPS26,CSNK1D,BYSL,DDX52 |
| 1.621e-05 | -11.03 | GO_PROTEIN_UBIQUITINATION_INVOLVED_IN_UBIQUITIN_DEPENDENT_PROTEIN_CATABOLIC_PROCESS | MSigDB lists | GO_PROTEIN_UBIQUITINATION_INVOLVED_IN_UBIQUITIN_DEPENDENT_PROTEIN_CATABOLIC_PROCESS | 127 | 38 | 17377 | 2626 |
TRIP12,KLHL21,PTTG1,CUL1,UBE2Z,CCNB1,ANKIB1,WWP2,HERC3,MDM2,KLHL20,SIAH1,HUWE1,ANAPC7,RNF19A,UBE3B,UBE3C,PLK1,RBX1,CUL3,RFFL,ANAPC2,AURKB,SYVN1,UBE4B,CDC23,CDC16,KEAP1,CDC27,RPS27A,KLHL15,SIAH2,TRIM32,RNF14,UBE2C,SMURF1,DDB1,ANAPC4 |
| 1.624e-05 | -11.03 | GO_STRUCTURAL_CONSTITUENT_OF_NUCLEAR_PORE | MSigDB lists | GO_STRUCTURAL_CONSTITUENT_OF_NUCLEAR_PORE | 13 | 9 | 17377 | 2626 |
NUP188,NUP107,NUP54,NUP62,NUP153,NUP155,NUP85,NUP205,TMEM33 |
| 1.638e-05 | -11.02 | GSE8621_LPS_PRIMED_UNSTIM_VS_LPS_PRIMED_AND_LPS_STIM_MACROPHAGE_DN | MSigDB lists | GSE8621_LPS_PRIMED_UNSTIM_VS_LPS_PRIMED_AND_LPS_STIM_MACROPHAGE_DN | 184 | 50 | 17377 | 2626 |
CCNC,NDUFA5,NDUFB6,DEPDC1,URB2,DAP,SRGN,NKRF,SDF2L1,BLM,S1PR2,ATG4A,KRR1,FASTKD3,MTMR4,SIVA1,HADHB,PARL,RP2,HDHD2,MYO5A,TSHZ1,EMB,TAOK1,LACTB,SCFD2,MTMR6,CCDC34,UHRF1BP1,PITPNB,BRCA1,RAB1A,KDM1B,RAD54B,MASTL,SRSF1,HSPA4,ZNF330,DCK,ZNF367,PROSER1,ACLY,NUP62,ASNA1,AKNA,RRS1,ZBTB11,LTA4H,OAZ1,ADNP2 |
| 1.638e-05 | -11.02 | GSE25088_ROSIGLITAZONE_VS_IL4_AND_ROSIGLITAZONE_STIM_STAT6_KO_MACROPHAGE_DAY10_DN | MSigDB lists | GSE25088_ROSIGLITAZONE_VS_IL4_AND_ROSIGLITAZONE_STIM_STAT6_KO_MACROPHAGE_DAY10_DN | 184 | 50 | 17377 | 2626 |
SEPHS2,CCDC93,GCLM,KARS,TXN,PARP12,SEC61G,TAP1,UBE2Z,RRAGC,EBNA1BP2,POMP,SND1,FKBP2,RBM17,GNS,RRN3,ATP13A3,RPN2,FNIP2,TAP2,C8orf59,OSTC,TFG,ABCC1,SRSF10,SNX8,GTF3C6,ADAM17,POLR2D,TUFM,PSMA1,RAB1A,MCM2,PSMB9,TOLLIP,DDX39A,LSG1,SERP1,ABCF1,MAT2A,DERL1,ATP6V1D,ETS2,TWSG1,HPS5,GADD45B,PITPNA,APOL2,ZNF146 |
| 1.638e-05 | -11.02 | GSE22527_ANTI_CD3_INVIVO_VS_UNTREATED_MOUSE_TREG_DN | MSigDB lists | GSE22527_ANTI_CD3_INVIVO_VS_UNTREATED_MOUSE_TREG_DN | 184 | 50 | 17377 | 2626 |
GLT8D1,GOLPH3L,RPS6KA1,TOR3A,KIAA0232,RRAGC,CTCF,ORC1,SNRPD3,XPO7,DCUN1D4,REEP5,EXT2,RSAD1,OIP5,SNRNP25,SMC3,TNFAIP8,SYNM,FUT8,PTGES3,GLE1,UBE3B,SLC35A1,KDM3B,TELO2,PTPN18,TSTA3,KAT7,CIRBP,SEPT8,EDF1,CDC23,SLC25A5,GLOD4,CAND1,KRIT1,PRIM1,PDCD6,FNTA,DSN1,BIRC5,ELMO1,FASTK,ARNTL,IARS2,ZDHHC7,PPP5C,CCNB2,PURA |
| 1.638e-05 | -11.02 | GSE5589_UNSTIM_VS_45MIN_LPS_STIM_MACROPHAGE_UP | MSigDB lists | GSE5589_UNSTIM_VS_45MIN_LPS_STIM_MACROPHAGE_UP | 184 | 50 | 17377 | 2626 |
UBL3,USP7,KIF3B,EIF3D,CHD1L,NKD2,MOGS,KLF13,SMC6,PRPF18,SNRNP25,ARPC5,LRRC8D,CS,ORAI1,RPN2,TARDBP,TECR,MYBL1,PPA1,GCC1,S100A6,ABHD2,KLF10,NCK1,SNRPB,KAT7,ELP4,KRAS,OGFR,MPG,DDX39A,PSMB9,RPSA,TFEB,YIF1A,EIF3K,HLA-B,DNAJC10,ZNF862,FNTA,CCDC6,DCK,STAT6,NLRC5,RBMS1,DUSP11,SASS6,RPS26,PFKP |
| 1.638e-05 | -11.02 | GSE19941_UNSTIM_VS_LPS_AND_IL10_STIM_IL10_KO_MACROPHAGE_DN | MSigDB lists | GSE19941_UNSTIM_VS_LPS_AND_IL10_STIM_IL10_KO_MACROPHAGE_DN | 184 | 50 | 17377 | 2626 |
ANKRD27,FOXM1,C1orf112,MRPL39,TMEM109,XIAP,CDCA8,RACGAP1,PMF1,PSMD9,PIP4K2A,TUBGCP2,MEAF6,SPAG5,RPA2,MRPL50,ERH,CENPJ,SSBP3,TANK,XRCC2,MSH2,CENPM,OSTC,RNF26,CHTOP,NSUN4,PLK1,TDP1,KIAA0040,HEBP2,ITM2A,SMC2,MTR,GINS4,PRIM1,MRPL2,CDKN2AIPNL,KIF18A,PALB2,POLE,CSK,CCDC14,DCK,CDCA5,PPA2,GEN1,ARHGAP23,TRAF5,FAF1 |
| 1.638e-05 | -11.02 | GSE3039_CD4_TCELL_VS_NKT_CELL_UP | MSigDB lists | GSE3039_CD4_TCELL_VS_NKT_CELL_UP | 184 | 50 | 17377 | 2626 |
SEPHS2,CYTIP,HECA,UBE2E2,NSMCE4A,CDS2,SHPRH,CCM2,AP3M2,NOTCH2,MXD4,B4GALT4,CDIPT,MBD4,SH3BP1,CISD2,PIK3IP1,CREB1,PIKFYVE,SCYL3,ARID4A,NCOA2,CGGBP1,PDLIM2,ANKLE2,CDKN2AIP,ARHGAP17,ERMP1,SEPT9,DENND1B,MTMR12,RIT1,ARID1A,TAZ,NDRG3,ARMC8,KRIT1,HAUS8,VEZF1,HNRNPH3,ZDHHC7,MDH1,YY1,BTBD10,MYO9A,CCDC125,LRP8,PDCD2L,HIPK3,PDCD4 |
| 1.638e-05 | -11.02 | GSE360_L_MAJOR_VS_B_MALAYI_LOW_DOSE_MAC_DN | MSigDB lists | GSE360_L_MAJOR_VS_B_MALAYI_LOW_DOSE_MAC_DN | 184 | 50 | 17377 | 2626 |
RAB14,SART1,NPHP4,MAPRE1,RPS6KA1,RAE1,TOR1AIP1,LANCL1,ORC1,SNRPD3,GGA2,PMVK,NDUFS7,NFATC3,NDUFV1,PDCD10,MED8,DPYSL2,ARHGEF1,SEPT11,CDKN1B,RPN2,CYC1,ATP6V0D1,CPNE1,SHOC2,ERCC1,AATF,TSTA3,PRRC2A,USP10,DCTD,TOMM40,CYFIP2,TAZ,IRF5,CHAF1A,MFN2,PI4K2A,UPF1,HSPB11,DHX16,HNRNPR,WDR7,COX5A,IMPDH1,TFDP2,AP2S1,NUDT3,DDX52 |
| 1.642e-05 | -11.02 | HALLMARK_DNA_REPAIR | MSigDB lists | HALLMARK_DNA_REPAIR | 141 | 41 | 17377 | 2626 |
POLA2,POLR2K,RAE1,SRSF6,EIF1B,SNAPC4,BCAP31,SAC3D1,GTF2F1,RPA2,PCNA,DAD1,DUT,ARL6IP1,MRPL40,ZNRD1,TMED2,GPX4,ERCC1,POLR2I,RFC3,GUK1,POLR2G,RBX1,POLR2D,POLR3GL,EDF1,MPG,RFC2,POLR2A,PRIM1,SEC61A1,POLR2J,DGCR8,CANT1,TAF12,USP11,TAF6,DDB1,AAAS,SSRP1 |
| 1.642e-05 | -11.02 | KIM_ALL_DISORDERS_DURATION_CORR_DN | MSigDB lists | KIM_ALL_DISORDERS_DURATION_CORR_DN | 141 | 41 | 17377 | 2626 |
EXOC3,CHMP2A,SUCLG1,DHPS,GNPDA1,KLHL21,DNAJB2,DCTN2,STARD7,COX4I1,CDIPT,HCFC1R1,BCAP31,NDUFS7,SAC3D1,SF3B2,ATP6V0B,PIN1,AHSA1,AKR1B1,NDUFS8,TALDO1,NUDC,NIPSNAP1,AMPD2,RNPS1,TUFM,FBXO9,TMEM147,ESYT1,NDUFA7,NDUFB1,PEF1,EIF3G,SNRPA,MAPK3,DTX4,COX8A,RUVBL2,ARRB2,HRAS |
| 1.656e-05 | -11.01 | prespliceosome | cellular component | GO:0071010 | 22 | 12 | 18223 | 2701 |
SNRPB,XAB2,LUC7L3,SF3B1,CRNKL1,SNRPG,SNRPD3,PRPF39,SNRNP70,LUC7L,SF3A2,LUC7L2 |
| 1.657e-05 | -11.01 | KHDRBS2 (KH RNA binding domain containing, signal transduction associated 2) | protein interactions | 202559 | 98 | 33 | 17029 | 2761 |
USP7,EWSR1,ARID2,SUZ12,HNRNPUL2,CUL1,LYN,HNRNPA2B1,MTA1,MRPS27,NABP1,YBX1,RBM3,TARDBP,CHTOP,YTHDC1,ILF3,CIRBP,NUSAP1,MAPK3,DDX17,SYNCRIP,HNRNPR,HNRNPH3,PTER,RBMX,ACOX1,SAFB,AEN,DDX5,KLHL42,WDR45B,HNRNPDL |
| 1.657e-05 | -11.01 | RPS17 (ribosomal protein S17) | protein interactions | 6218 | 98 | 33 | 17029 | 2761 |
RPS15,RPS2,CYLD,RPLP2,CUL1,CDC73,RPL23A,PTEN,HUWE1,ZNF746,RPL19,CRY2,TARDBP,NUDC,VHL,CUL3,ILF3,RPL8,RPL6,RPS10,RPS24,MCM2,RPS9,RPSA,CAND1,RPLP1,WDR76,FAU,RRS1,SMURF1,ARRB2,CDK2,RPS26 |
| 1.659e-05 | -11.01 | PRPF38A (pre-mRNA processing factor 38A) | protein interactions | 84950 | 47 | 20 | 17029 | 2761 |
POLA2,ZCCHC10,CHERP,SRSF6,RNPS1,DHX8,CSNK2A1,JMJD6,SRSF5,APP,MFAP1,DNAAF2,PPIG,SRSF4,MAPK6,SRSF3,CFAP20,NKAPD1,IFI16,SRPK2 |
| 1.659e-05 | -11.01 | PUS1 (pseudouridylate synthase 1) | protein interactions | 80324 | 47 | 20 | 17029 | 2761 |
PPP1R12A,ACTR3,TRMT6,NSUN2,MRPL12,TUFM,VPS25,RPA1,GTF2F1,FARSA,PFDN5,PCNA,IDE,SP100,GATC,PFDN4,PSMD8,PPM1G,NMD3,VPS29 |
| 1.659e-05 | -11.01 | MRPL32 (mitochondrial ribosomal protein L32) | protein interactions | 64983 | 47 | 20 | 17029 | 2761 |
DDX28,MRPL9,MRPL42,MRPL39,MRPL12,MRPS26,ILF3,STOML2,MRPL50,MRPL2,MRPL55,MPV17,MRPL40,RRS1,MRPL11,MRPL21,HNRNPDL,ZC3H3,MRPL57,FUBP1 |
| 1.659e-05 | -11.01 | tRNA metabolic process | biological process | GO:0006399 | 188 | 51 | 17256 | 2622 |
SEPHS2,CTU2,KARS,TP53RK,MRPL39,TRMT6,LAGE3,C2orf49,GTPBP3,FARSA,EXOSC7,IARS,GATC,DUS4L,ELP5,THADA,GRSF1,TRMU,POP7,RTCB,DUS2,CPSF4,PPA1,CARS2,METTL1,RPP25,LARS,GTF3C6,HARS,NSUN2,TYW1,METTL2A,ELP4,EXOSC9,POLG2,TARS,EPRS,DUS3L,LSM6,QARS,WDR4,TYW5,IARS2,FTSJ1,PPA2,QRSL1,TRMT10B,DTD1,OSGEPL1,TSEN15,TYW1B |
| 1.659e-05 | -11.01 | Interactions of Vpr with host cellular proteins | REACTOME pathways | R-HSA-176033 | 36 | 17 | 10287 | 1696 |
NDC1,NUP188,RAE1,NUP54,NUP155,SLC25A5,NUP205,KPNA1,NUP210,BANF1,NUP107,NUP153,NUP62,NUP58,NUP85,AAAS,SEH1L |
| 1.668e-05 | -11.00 | GO_TRANSCRIPTION_FACTOR_BINDING | MSigDB lists | GO_TRANSCRIPTION_FACTOR_BINDING | 514 | 113 | 17377 | 2626 |
RORB,TCF12,USP7,TRERF1,ADD1,TSC22D3,TRIM11,SMARCA4,SIRT2,UBE2I,MAPK14,RCOR3,PARK7,CREM,USF1,PSMA6,SP100,MTA1,ZNHIT6,SRI,NOC2L,RNF19A,TP53BP2,ATF2,CDC5L,CPNE1,ERCC1,VHL,RNF25,HNRNPF,DDX20,NFATC2,MEF2D,DOT1L,BRMS1,HHEX,SMAD2,RBL1,E2F4,MAFK,HIPK2,ARNTL,OGT,ACTB,TRIM32,NCOA1,TFDP2,E2F2,MAPK1,PDCD11,PSMC1,SMAD4,HDAC2,NCOR2,TRIP12,MECP2,TCF3,CENPF,DHX9,CHCHD2,MEF2A,HMGN3,THRAP3,ETS1,PSMD9,FOXO3,MAD2L2,WWP2,GTF2F1,IRF4,RB1,MLX,HDAC7,FAM89B,ARHGEF2,BRD7,MDFIC,BCL2,CREB1,FBL,STAT3,NCOA2,EEF1D,KAT2A,CREG1,PRKDC,MTA2,LDB1,RCOR1,ELK1,PRMT2,DAPK3,PSMC4,RXRB,CAND1,KEAP1,SETD3,PITX1,TFDP1,CEBPG,E2F1,PIAS2,NUP62,HMGB2,YWHAZ,RBPJ,RUVBL2,TAF12,USF2,PURA,CDKN2A,IFI16,FAF1 |
| 1.670e-05 | -11.00 | GSE11057_NAIVE_VS_MEMORY_CD4_TCELL_DN | MSigDB lists | GSE11057_NAIVE_VS_MEMORY_CD4_TCELL_DN | 189 | 51 | 17377 | 2626 |
UBL3,SMAP1,PLXNC1,FAM129A,SRGN,TOR3A,PTTG1,CBLL1,SMC6,REEP5,SPPL2A,CAPN2,GSTK1,ETV6,TANK,ARL6IP1,PRC1,CLDND1,TAGLN2,RNF135,PDIA6,GNAI2,MYBL1,MYO5A,ELOVL5,EMB,LDHA,EZR,ATXN1,OGDH,VDAC1,KLF6,PRDX1,OPTN,MYO1F,FAS,AHNAK,GOLGA7,PSMD8,ITGB1,SIAH2,HMGB2,ACTB,CTSA,PIEZO1,MAP3K5,EHD4,YWHAH,RNF139,IFI16,PFKP |
| 1.670e-05 | -11.00 | GSE17721_12H_VS_24H_CPG_BMDC_DN | MSigDB lists | GSE17721_12H_VS_24H_CPG_BMDC_DN | 189 | 51 | 17377 | 2626 |
BCCIP,RHOG,UNK,MRPL42,MUT,LUZP1,CASP6,CHERP,GNPDA1,CDK2AP2,BABAM1,HABP4,LAGE3,ABHD14B,CLCC1,MAP1LC3B,PARN,STMN1,PARK7,NDUFS7,PSMA6,PTEN,IMPAD1,LPIN2,CDKN1B,MTX2,TMED2,NTPCR,ELOVL5,ERMP1,ABCF2,TEX10,MRPL12,MTMR6,HTATIP2,PRKRA,CBFA2T2,TXNL4A,PRDX1,SH3GLB1,CYB5A,CHCHD3,OSBPL11,UBXN2B,STAT6,AXIN1,ERGIC3,RNF38,LRPPRC,COX5A,YY1 |
| 1.670e-05 | -11.00 | GSE15330_LYMPHOID_MULTIPOTENT_VS_GRANULOCYTE_MONOCYTE_PROGENITOR_IKAROS_KO_DN | MSigDB lists | GSE15330_LYMPHOID_MULTIPOTENT_VS_GRANULOCYTE_MONOCYTE_PROGENITOR_IKAROS_KO_DN | 189 | 51 | 17377 | 2626 |
SLC12A7,UBL3,CCNC,CDS2,LIME1,TMEM184B,TRIP10,DAP,SLC41A1,GADD45G,KCTD17,TM9SF3,RACGAP1,HAUS4,PLXNA1,PPP3CB,TMED3,RAB11A,EEF2K,PRNP,ATP6V0B,SAR1A,MTMR4,RALB,BANF1,TIPARP,FRMD8,GM2A,KLF10,EID1,LRBA,MYBL2,RFFL,EMP3,UBE2V1,GORASP2,PLEC,SHCBP1,LSG1,ERC1,ARF4,MAPK3,NECAP2,ATP6V1D,AHNAK,SNAP29,STK38,NFIL3,PIAS2,ADAM9,VPS29 |
| 1.670e-05 | -11.00 | GSE33162_UNTREATED_VS_4H_LPS_STIM_HDAC3_KO_MACROPHAGE_UP | MSigDB lists | GSE33162_UNTREATED_VS_4H_LPS_STIM_HDAC3_KO_MACROPHAGE_UP | 189 | 51 | 17377 | 2626 |
PTMS,TXN,NDUFB6,TMBIM4,GNPDA1,TMEM97,TPX2,SDF2L1,RAB11A,REEP5,GNB2,FLAD1,FKBP1A,CAPN2,NUDT19,CDKN2C,SNRNP25,ARPC5,SEPT11,CDC25B,TALDO1,TMEM14C,DNMT1,HTRA2,ALDH9A1,PLK1,CYFIP1,SSR2,WDHD1,AURKB,MCM2,RFC2,SNRPA,ECH1,ASF1B,PRIM1,CAT,MID1IP1,CDKN2AIPNL,FAM110A,TOMM6,TFDP1,MRPL27,MAPK6,H2AFX,ITGB1,COX5A,CDK2,YWHAH,UBE2C,SSRP1 |
| 1.670e-05 | -11.00 | GSE17721_POLYIC_VS_CPG_12H_BMDC_DN | MSigDB lists | GSE17721_POLYIC_VS_CPG_12H_BMDC_DN | 189 | 51 | 17377 | 2626 |
SRM,HJURP,MPHOSPH8,SRSF6,USP39,JMJD6,GTF3A,CLCC1,LYRM2,KCMF1,RPA2,FARSA,SLC31A1,RRN3,NFATC3,MED8,NDUFB4,ZNF639,RNASEK,NOC2L,HADHB,AKR1B1,ECD,RNF26,LRRC59,MYO5A,ABCC1,FDFT1,SRSF10,EIF5A,RHOA,MRPL12,TUBGCP5,PSMG1,FAM133B,EIF4G2,CYB5A,SRSF1,DNAJC10,HSPA4,HINT1,STT3A,TOMM6,TPP2,ACLY,FAM122A,CHID1,DDB1,GPATCH4,BYSL,SSRP1 |
| 1.674e-05 | -11.00 | GO_STRUCTURE_SPECIFIC_DNA_BINDING | MSigDB lists | GO_STRUCTURE_SPECIFIC_DNA_BINDING | 118 | 36 | 17377 | 2626 |
H2AFZ,SUZ12,MECP2,CTCF,SMARCA4,HMGN3,BLM,FOXO3,MBD2,XRCC2,MSH2,H2AFY,SMARCE1,STAT3,MSH6,ERCC1,HMGN1,HMGN5,HMGN4,MTA2,WBP2,MEN1,MBD3,HMGN2,RAD51C,RAD18,NEIL3,ACTB,XRCC3,HMGB2,RUVBL2,YY1,RBBP4,H3F3A,HDAC2,RAD51D |
| 1.683e-05 | -10.99 | GO_ENDOPLASMIC_RETICULUM | MSigDB lists | GO_ENDOPLASMIC_RETICULUM | 1526 | 288 | 17377 | 2626 |
RAB14,TMED7,PDCD6IP,TMEM203,ADAM10,PRKCSH,PIGQ,TMEM109,TAP1,AGPAT1,IKBIP,PARK7,CYB5RL,TTC9C,CISD2,MARCH2,SPTSSA,LRRC59,SRP72,BAK1,PGAP2,USO1,ATG9A,MCFD2,ICMT,RAB2B,PLEKHF2,STT3A,TMED10,RRS1,RTN3,SVIP,PPIB,SEC61G,HLA-E,KCTD17,TMED3,NOTCH2,SLC35B1,PSEN1,COPG2,COPB2,NPLOC4,DDRGK1,CD59,FKBP1A,RNF121,RPN1,LRRC8D,DAD1,PIGG,PCYT2,LPCAT1,TMED2,EEF1D,FDFT1,EIF5A,PIGT,SIGMAR1,PGS1,MAN1B1,RDH10,PIP4K2C,SSR2,MAP2K2,CYB5A,RDH11,SEC31A,CAT,DERL1,TXNDC16,ERGIC3,LPCAT4,VCPIP1,SAMD8,SMPD4,MAP3K5,RNF139,RHOG,ATXN3,CAST,ANK3,RAC1,VTI1A,TMEM97,ADPGK,POMP,SLC35B2,LCLAT1,APP,KTN1,EPM2A,CD320,RAB21,ATP2A2,LPIN2,ANKRD13C,TAP2,CLN6,ANKLE2,SEC61B,ERMP1,ATP13A1,DNAJA1,TMEM147,PKMYT1,RAB1A,SERP1,FKBP3,SEC61A1,DDOST,CERS6,SEL1L,NCLN,ATF6,MBOAT1,AGPAT3,SDF2L1,POFUT1,WRB,HLA-A,EBP,CAPN2,CRAT,AHSA1,ANXA5,OSTC,CNPY3,NCOA2,PACS2,TMX1,STAU1,KCNQ1,ZP3,ARSK,PDE3B,SPPL2B,YIF1A,NUCB1,PLD3,KEAP1,MAGT1,WNT5B,DBI,STX18,PML,ASNA1,FAF1,ESYT2,PIGM,COPA,YTHDC2,MOGS,FKBP2,CDIPT,BECN1,SEC16A,RNF103,PRNP,SSR1,DST,NUP210,CDC42,RAB35,PHTF1,HADHB,SRI,ZFYVE27,TECR,DPM1,APH1A,NCK1,VHL,LRBA,PSMG1,SUMF2,LRP5,ESYT1,PITPNB,KRTCAP2,STX16,LSG1,RHEB,ALG3,TRAM2,AGPAT2,MIA2,CLU,PIEZO1,CLN3,PIGN,AGTRAP,UBXN1,CIB1,RAB6A,RHBDD1,NUS1,VMP1,EI24,ARL6IP1,SLC27A4,KIFAP3,BCL2,KDELR1,PREB,TRAPPC9,NSDHL,ERLIN1,ACSL3,SYVN1,VKORC1,MOSPD3,GALNT2,ORMDL2,SYNCRIP,SIL1,CTSA,EHD4,PTDSS1,APOL2,TMEM106C,CHERP,COPE,TMX4,CLCC1,BCAP31,EXT2,SEC11A,UBXN2A,SAR1A,BCAP29,RPN2,CYB5R1,AHCYL1,LMAN1,MINPP1,PDIA6,ABI1,HTRA2,ACSL5,UBQLN4,FAM172A,SLC26A6,TOR1AIP2,EDEM2,RHBDF2,DNAJC10,ATP1A1,SURF4,HNRNPR,SCAP,UBXN2B,CANT1,FKBP5,REEP4,ABCA1,TMEM33,CDS2,TOR3A,TMX3,NKRF,SUMF1,DNAJB9,MAN1A1,SPPL2A,PTPN2,FGFR3,SEC24C,RRBP1,ZDHHC13,SLC35B4,ANP32A,CAMK2G,MYO5A,RNF5,ELOVL5,MLEC,RHOA,PNPLA8,HLA-B,RAB18,PDCD6,SEC23IP,OSBPL8,PGRMC1,PKD2,SPCS3,PLOD3 |
| 1.688e-05 | -10.99 | DNA-dependent DNA replication | biological process | GO:0006261 | 122 | 37 | 17256 | 2622 |
POLA2,MCM10,THOC1,TWNK,CDT1,ORC1,BLM,RPAIN,NEXMIF,RFWD3,RPA2,PCNA,MCM5,TIMELESS,RNASEH2A,ORC3,MCMBP,GINS1,RFC3,PRIM2,HELB,WDR18,WDHD1,SLBP,CDC6,MCM2,RFC2,POLG2,GINS4,PRIM1,RPA1,UPF1,POLE,TONSL,ZNF830,PURA,POLQ |
| 1.692e-05 | -10.99 | GORASP2 (golgi reassembly stacking protein 2) | protein interactions | 26003 | 115 | 37 | 17029 | 2761 |
MIF,TMED7,EWSR1,AAMDC,FLOT1,TMED3,MAP1LC3B,MAPK14,SCYL2,APP,CDK5,DPYSL2,KIF14,TXLNA,ARL6IP1,TECR,TMED2,RHOA,PRRC2A,NQO2,TMEM216,CUL3,DCTD,SEPT7,RAB1A,CDC23,ODC1,SH3GLB1,RAD54B,AHNAK,GOLGA2,PDLIM1,PRDX3,TMED10,NUP62,TRAF5,MAPK1 |
| 1.692e-05 | -10.99 | BCL2 (BCL2, apoptosis regulator) | protein interactions | 596 | 115 | 37 | 17029 | 2761 |
TOMM20,DYNLL1,RAF1,CYCS,BCL2L1,UBE2I,PRKACA,PSEN1,MAPK14,BECN1,BCAP31,MOAP1,CAPN2,ATP2A2,PIN1,BCL2,CISD2,TP53BP2,BAK1,PPP3CA,NRAS,BCLAF1,KRAS,PKMYT1,BRCA1,VDAC1,MAT2A,RHEB,NMT2,MAPK3,PPP2CA,PPP2R5A,PML,CDK2,MAPK1,RTN3,HRAS |
| 1.696e-05 | -10.98 | - | gene3d domains | 3.30.40.10 | 446 | 104 | 8148 | 1295 |
MIB2,TRIM41,ASH1L,TRAF7,KMT2E,KDM4A,PHRF1,TRIM11,XIAP,USP39,ZFYVE21,NSD3,RUFY1,TCF19,TRIM65,ANKIB1,RNF103,USP5,FANCL,CYHR1,MDM2,KDM2A,BRPF3,SIAH1,MTMR4,ZFYVE27,INTS12,TTC3,MARCH2,RNF19A,RNF26,RNF169,RLIM,PRPF19,TRIM8,BAZ2A,RBX1,RNF25,PCGF6,LNX2,TOPORS,USP22,BRCA1,DIDO1,KMT2C,TRIM28,PLEKHF2,TRIM4,TRIM47,RAD18,CHD3,NSMCE2,UHRF2,RNF38,BAZ1B,TRIM32,TRIM52,TRAF5,USP13,PHF23,SHPRH,BRAP,CBLL1,ZNRF3,UBE4A,RFWD3,RNF121,MEX3C,RNFT1,ZNRF2,PHF14,PPIL2,LTN1,PIKFYVE,RNF135,FBXL19,GTF2H2,LRSAM1,SYTL3,RNF5,PHF20L1,PHF10,TRAFD1,LONRF3,ZMYND11,RFFL,SYVN1,UBE4B,PCGF1,PHF6,MTMR3,HGS,COMMD3-BMI1,TRIM26,DTX4,SIAH2,PIAS2,PML,KMT2B,USP20,ZMIZ1,RNF14,RNF139,RNF114 |
| 1.697e-05 | -10.98 | fibrosarcoma | COSMIC cancer mutations | fibrosarcoma | 32 | 15 | 17385 | 2587 |
GNAS,CDKN2C,RB1,EWSR1,NRAS,NF1,PTEN,SF3B1,ETV6,RAC1,STK11,KRAS,FUS,HRAS,CDKN2A |
| 1.700e-05 | -10.98 | nucleosome binding | molecular function | GO:0031491 | 69 | 25 | 17224 | 2647 |
HMGN1,H2AFZ,HMGN5,HMGN4,MTA2,MUM1,SMARCA4,HMGN3,ARID1A,MBD3,HMGN2,SUPT16H,MBD2,NOC2L,H2AFY,ACTB,CABIN1,NAP1L4,H3F3A,RBBP4,SMARCE1,SAP30L,HDAC2,RNF169,HP1BP3 |
| 1.707e-05 | -10.98 | NCBP1 (nuclear cap binding protein subunit 1) | protein interactions | 4686 | 128 | 40 | 17029 | 2761 |
UNK,THOC1,IVNS1ABP,SUZ12,GSPT2,CERK,CUL1,LETMD1,CCNB1,SRRT,FERMT3,LYAR,GART,HUWE1,AP1M1,TARDBP,NAP1L4,MVP,STAU1,SNX2,HNRNPF,CUL3,DDX20,SLBP,MPG,EIF4G2,LUC7L,ERC1,SF3A2,CAND1,KPNA4,UPF1,SEC23IP,PPM1G,KPNA2,SNRNP70,NKAPD1,APOL2,SMAD4,IFI16 |
| 1.707e-05 | -10.98 | TBK1 (TANK binding kinase 1) | protein interactions | 29110 | 128 | 40 | 17029 | 2761 |
DDX58,MIB2,CYLD,AGO2,XIAP,CUL1,SIKE1,IRF3,CNTROB,MAP1LC3B,APP,ANKRD28,CTNNBL1,TANK,TXLNA,PPP6C,MAVS,CEP63,PPP6R1,NCOA2,TRIM14,CDC37,PLK1,TNFAIP3,RB1CC1,ATG9A,NCK1,PBXIP1,AZI2,MCM2,IRF5,OPTN,TRIM26,ODF2,DTX4,TICAM1,PPP6R2,SASS6,SMURF1,TRAF5 |
| 1.712e-05 | -10.98 | ZCRB1 (zinc finger CCHC-type and RNA binding motif containing 1) | protein interactions | 85437 | 62 | 24 | 17029 | 2761 |
NOL12,NIFK,RPS2,SF3B1,CTCF,PDCD7,GAR1,MAK16,RPSA,KRR1,SF3B2,KRI1,NSA2,UPF1,CCDC86,RPS27A,H2AFY,YBX1,RPL19,RRS1,SNRNP70,ZBTB11,PURA,ZC3HAV1 |
| 1.712e-05 | -10.98 | ORC2 (origin recognition complex subunit 2) | protein interactions | 4999 | 62 | 24 | 17029 | 2761 |
MCM10,FOXM1,KAT7,CDT1,RBM8A,DBF4,CDC6,SIRT2,BRCA1,ORC1,FXR1,MCM2,KIF11,LMNA,RPA1,XRCC5,RPA2,CCNA2,RAD18,MCM5,ORC3,CDK2,TERF2,CDC5L |
| 1.712e-05 | -10.98 | SEC61A1 (Sec61 translocon alpha 1 subunit) | protein interactions | 29927 | 62 | 24 | 17029 | 2761 |
RPS15,STAU1,SEC61B,CYLD,SEC61G,ADRB2,BCAP31,SERP1,HLA-A,NCDN,SEC61A1,DDOST,MAGT1,RPL17,RPS14,PPP4R1,NUP107,AP1S1,RPL19,YWHAZ,ASNA1,TECR,USP11,CLN3 |
| 1.714e-05 | -10.97 | protein domain specific binding | molecular function | GO:0019904 | 648 | 139 | 17224 | 2647 |
ST13,ADAM10,PHRF1,TRIM11,CNTROB,UBE2I,RUFY1,CALM2,CDC42,ETV6,DNM2,TRA2B,SRSF10,CDC5L,SRP72,ERCC1,AATF,NCK1,EHMT1,LNX2,EZR,MCL1,WBP1,LUC7L,CHAF1A,DPYSL3,CXXC4,HHEX,WAS,SMAD2,E2F4,AXIN1,ADAM9,STK11,VPS4A,TFDP2,RRM1,SDC2,DLGAP4,STRN4,PMF1,RAB6A,PSEN1,RB1,VASP,INPP5A,MBD2,BANF1,XPA,CTR9,BCL2,OSTF1,ACSL3,LDB1,KRAS,MAP2K2,DAPK3,POLR2J,ETS2,NSF,RBMX,EXOC4,PPP3R1,NUP62,YWHAZ,MAP3K5,NDE1,CDK2,TCF12,WASF2,CHMP2A,PTTG1,MYH9,IRF3,BCL2L1,DAZAP2,LYN,PRKACA,APP,REPS1,MDM2,CCNA2,SP100,SH3BP1,KIF14,TP53BP2,MAVS,ABI1,DVL2,CLCN3,ARHGAP17,CUL3,SLC26A6,WIPF1,DNAJA1,CADM1,CHMP2B,SHCBP1,ERC1,TRIM28,SOCS7,SRSF1,MECP2,DAP,TRAK1,ARFIP2,PAWR,LANCL1,ARF1,GTF2F1,PTEN,CENPJ,FUT8,CITED2,NCOA2,MYO5A,HNRNPM,ADAM17,PRKDC,FADD,HSPA1B,CBX3,CNOT9,SH3BP5,HGS,KEAP1,ELMO1,CCDC6,ACOX1,CAPN7,TFDP1,STX18,HMGB2,DDX5,PKD2,YWHAH,TERF1,DDB1,FAF1 |
| 1.719e-05 | -10.97 | GO_NUCLEOSIDE_TRIPHOSPHATE_METABOLIC_PROCESS | MSigDB lists | GO_NUCLEOSIDE_TRIPHOSPHATE_METABOLIC_PROCESS | 199 | 53 | 17377 | 2626 |
GALK1,COX5B,NDUFA5,COX15,NDUFV2,NDUFS1,NDUFB6,SUCLG1,UQCR10,MECP2,UCK2,OLA1,UCK1,NDUFA4,COX4I1,CYCS,ADPGK,ATP6V1B2,NDUFS7,NDUFS4,NDUFV1,NDUFA2,NDUFB4,DUT,MSH2,ATP6V0A2,NDUFB9,NDUFS8,CYC1,NDUFA3,TGFB1,AMPD2,GUK1,LDHA,ATP6V0A1,PFKFB3,NDUFA7,OGDH,NDUFB1,TAZ,HSPA1B,STOML2,NDUFA11,COX7A2L,TBPL1,COX8A,COX5A,DHTKD1,UQCRH,NDUFS5,GPI,PGAM1,PFKP |
| 1.720e-05 | -10.97 | ACTR3 (ARP3 actin related protein 3 homolog) | protein interactions | 10096 | 94 | 32 | 17029 | 2761 |
WASF2,UNK,TP53RK,PPP1R12A,DNAAF5,MYH9,EIF1B,CCP110,CDC42,ARPC5,TNPO3,CORO1A,TTLL12,RPRD1B,METTL1,ARHGAP17,CCT2,NSUN2,HNRNPF,RANGAP1,CAPZA2,MCM2,ANLN,ARPC1A,SH3GLB1,RPA1,CAT,TPD52L2,CORO1C,MYO18A,ACTB,FUBP1 |
| 1.720e-05 | -10.97 | DSTN (destrin, actin depolymerizing factor) | protein interactions | 11034 | 94 | 32 | 17029 | 2761 |
MIF,UNK,PTMS,ST13,TSTA3,WDR1,MEMO1,LDHA,MYH9,POMP,MCFD2,MCM2,SPR,PSMD9,PCBP1,ISG15,C12orf10,SEC23IP,SP100,STAT6,PRDX5,MYO18A,RRBP1,ITGB1,ACTB,DNPH1,PIEZO1,CDK2,PDLIM5,HTRA2,RNF114,LDHB |
| 1.720e-05 | -10.97 | FOXK1 (forkhead box K1) | protein interactions | 221937 | 94 | 32 | 17029 | 2761 |
MAX,FAM129A,MAPK14,ASXL2,FOXO3,ANKRD28,SAP130,TFAP4,ZNF428,RB1,VASP,AHCY,PHKG2,PPP6R1,ARID4A,DVL2,EEF1D,SAP30,AGGF1,RNPS1,PSMA1,UHRF1BP1,NFATC2,UBE4B,METTL22,BRMS1,GPS2,RBL1,TULP3,CHEK2,SINHCAF,HDAC2 |
| 1.727e-05 | -10.97 | OPA1 (OPA1, mitochondrial dynamin like GTPase) | protein interactions | 4976 | 40 | 18 | 17029 | 2761 |
GID8,UNK,ARHGAP17,NDUFS1,ILF3,CUL3,NIT2,MCM2,APP,ECH1,CAND1,SMAD2,PRDX3,PTPN7,HADHB,XRCC3,NDUFS8,HTRA2 |
| 1.727e-05 | -10.97 | SLIRP (SRA stem-loop interacting RNA binding protein) | protein interactions | 81892 | 40 | 18 | 17029 | 2761 |
PPIF,COA3,SCAMP3,EID1,BABAM1,RBM8A,RPL38,ILF3,CSNK2A1,ADRB2,EIF4G2,HAUS2,SUGP1,HNRNPA2B1,HNRNPR,LRPPRC,PQBP1,SNRNP70 |
| 1.730e-05 | -10.96 | GSE35825_UNTREATED_VS_IFNA_STIM_MACROPHAGE_UP | MSigDB lists | GSE35825_UNTREATED_VS_IFNA_STIM_MACROPHAGE_UP | 165 | 46 | 17377 | 2626 |
RMND5A,ANKRD13D,DNMT3A,TRERF1,ADO,UCK1,CNTROB,LACTB2,GGA2,RGS2,TWF2,DUSP22,TRIM65,CHKA,MAT2B,SMC3,DPYSL2,TBC1D14,SSBP3,JOSD1,MAVS,CNPY3,TPCN1,MED22,DEAF1,PSRC1,MBLAC2,TMEM126B,MTMR12,LRP5,POLG2,TAZ,BTBD1,USP36,SMAP2,FADD,AKAP1,MYO1F,ANKRD10,MID1IP1,NSF,FAM110A,CORO1C,MPV17,USP20,RAB3IL1 |
| 1.746e-05 | -10.96 | GO_RNA_HELICASE_ACTIVITY | MSigDB lists | GO_RNA_HELICASE_ACTIVITY | 66 | 24 | 17377 | 2626 |
DDX28,DDX47,SNRNP200,DDX24,DHX29,HELB,YTHDC2,DHX9,DDX20,DHX8,DDX39A,DHX15,DHX57,RAD54B,DDX17,DDX23,DDX56,UPF1,EIF4A3,DHX16,DDX31,DDX5,DDX52,DDX42 |
| 1.757e-05 | -10.95 | transcription cofactor activity | molecular function | GO:0003712 | 566 | 124 | 17224 | 2647 |
RORB,MAX,TRERF1,MAGED1,SMARCA4,TAF6L,IRF3,SND1,RCOR3,BIRC2,PARK7,MXD1,GLMP,SP100,MTA1,JAZF1,GMEB1,LPIN2,NOC2L,TAF5L,ECD,SMARCE1,ATF2,SAP30L,CCAR1,CARM1,RLIM,RYBP,SAP30,POU2AF1,PBXIP1,GABPA,ERF,EID1,DRAP1,WBP2,HTATIP2,EDF1,SUPT20H,USP22,BRCA1,SOX4,CBFB,USP21,TRIM28,DDX17,TONSL,HIPK2,PQBP1,ATF6,TRIM32,FUS,NCOA1,TFDP2,BEND6,CBX4,POU3F2,SLC30A9,NCOR2,EWSR1,MECP2,TCF3,DHX9,ARID5A,CTCF,MED13L,MEF2A,PAWR,PMF1,DNAJB1,MXD4,THRAP3,SUPT7L,PSMD9,ARID1B,YY1AP1,JMY,GTF2F1,TFAP4,SUB1,RB1,MED8,MED10,KMT5A,HDAC7,BUD31,BRD7,SS18L1,MAML1,CITED2,CREB1,NCOA2,MED22,DCAF6,KAT2A,CREG1,ZMYND11,LDB1,RFXANK,RCOR1,ARID1A,CBFA2T2,PRMT2,RXRB,PFDN5,SERTAD2,PDLIM1,GPS2,ZHX1,SETD3,MED15,TFDP1,NFIL3,SIAH2,PIAS2,TBPL1,RUVBL2,TAF12,NR2F2,YY1,RNF14,TOB1,N4BP2L2,SMARCD1 |
| 1.767e-05 | -10.94 | myxoid | COSMIC cancer mutations | myxoid | 16 | 10 | 17385 | 2587 |
GNAS,TCF12,RB1,EWSR1,NRAS,PTEN,KRAS,FUS,TFG,HRAS |
| 1.785e-05 | -10.93 | PELLICCIOTTA_HDAC_IN_ANTIGEN_PRESENTATION_UP | MSigDB lists | PELLICCIOTTA_HDAC_IN_ANTIGEN_PRESENTATION_UP | 62 | 23 | 17377 | 2626 |
TMED7,GOLPH3L,COPA,PSMA8,GOPC,COPE,PSMB7,POMP,PSMD9,BCAP31,COPG2,PSMB3,COPB2,PSMC4,GOLM1,PSMD2,PSMD1,SAR1A,TMED10,PSMD3,ERGIC3,SIL1,BCAP29 |
| 1.787e-05 | -10.93 | GSE21927_SPLEEN_VS_4T1_TUMOR_MONOCYTE_BALBC_DN | MSigDB lists | GSE21927_SPLEEN_VS_4T1_TUMOR_MONOCYTE_BALBC_DN | 170 | 47 | 17377 | 2626 |
DNAJC2,PRPF38B,PARP12,GNPNAT1,NOP2,RWDD1,NDUFB6,CDCA8,ENSA,ABCB10,XPNPEP3,CCNB1,SRRT,GFM2,RPL11,FAM192A,GART,NFATC3,AHSA1,AKAP8,EFTUD2,GTSE1,SUCLG2,BCAP29,MAML1,RNF26,MCMBP,ZC3H3,CDK12,SAP30,GTF3C6,PPT1,DENND1B,SNRPB,PRKDC,ATP2C1,TEX10,SLC16A7,PSMG1,FANCE,XRCC5,POLR2J,TONSL,TATDN2,CDCA7L,C1orf109,ACAT1 |
| 1.791e-05 | -10.93 | Bmpr1a (bone morphogenetic protein receptor, type 1A) | protein interactions | 12166 | 137 | 42 | 17029 | 2761 |
NDC1,IMMT,NDUFS1,TOR1AIP1,SLC2A1,TAP1,FLOT1,GLUD1,NOTCH2,SLC35B2,ATP6V1B2,PDXDC1,GNB2,TFRC,HLA-A,XPR1,ARL6IP6,WWP2,NDUFV1,GART,NDUFB4,SLC12A2,ATP6V0D1,RNF5,TIMM50,ERMP1,RAB7A,ERLIN1,ATP6V0A1,NDUFA7,CHMP2B,RAB1A,GOSR1,CHCHD6,STOML2,ATP1A1,AHNAK,JAK1,SLC16A1,CHMP4B,ATP5F1A,NDUFS5 |
| 1.798e-05 | -10.93 | WEIGEL_OXIDATIVE_STRESS_BY_HNE_AND_TBH | MSigDB lists | WEIGEL_OXIDATIVE_STRESS_BY_HNE_AND_TBH | 58 | 22 | 17377 | 2626 |
PPP3CA,ETV3,TSPAN31,TCF3,EZR,BCL2L1,LYN,ETS1,RXRB,CCNK,CAPN2,DST,ETS2,STAT6,IL6ST,FASTK,E2F1,CLU,CREB1,SMAD1,YWHAH,TERF1 |
| 1.827e-05 | -10.91 | HDAC3 (histone deacetylase 3) | protein interactions | 8841 | 224 | 61 | 17029 | 2761 |
MBD1,NCOR2,ATXN3,EWSR1,KDM4A,PHB2,SF3B1,CSNK2A1,SMARCA4,MEF2A,TOP2B,IRF3,WDR5,SEC16A,SAFB2,MAPK14,RCOR3,PAPOLA,RB1,HDAC7,PIN1,ETV6,PRDM4,PPP4R1,RBM15,STAT3,DNMT1,SAP30L,ARID4A,SAP30,CCT2,BIRC3,VHL,PRKDC,RCOR1,MEF2D,CBFA2T2,KLF6,CCT8,APPL1,TRIM28,ZMYM3,DDX17,BRMS1,HSPA4,RBL1,CHD3,TAB2,GPS2,SAFB,E2F4,MAFK,STAT1,PML,SIAH2,PIAS2,DDX5,YY1,RBBP4,DDB1,SMARCD1 |
| 1.827e-05 | -10.91 | PSMC5 (proteasome 26S subunit, ATPase 5) | protein interactions | 5705 | 224 | 61 | 17029 | 2761 |
RORB,KIF3B,RECQL,CYLD,ATXN3,ZCCHC8,SIKE1,IKBIP,WDR5,PSMD9,SDHA,KCMF1,UBLCP1,RAD23A,PTPN2,HERC3,RPN1,PSMD2,MDM2,PSMD1,PSMA6,SIAH1,ABRAXAS2,HUWE1,UCHL5,FBXO7,RAD23B,CRY2,ECD,UBE3C,FGFR1OP2,ABCC1,CDC5L,MOB4,SHOC2,GCC2,RPL29,PSMA8,HARS,STRIP1,IDH3A,CUL3,PSMB7,PSMA1,BRCA1,DNAJA1,CAPZA2,EDEM2,PSMB9,ABCF1,PSMB3,PSMC4,PSMD8,PSMD3,SSNA1,MAP3K5,CDK2,ECPAS,SMURF1,PSMC1,TUBB |
| 1.828e-05 | -10.91 | MXD1 (MAX dimerization protein 1) | protein interactions | 4084 | 30 | 15 | 17029 | 2761 |
SAP130,BRMS1,MAX,MLX,SMC3,PTEN,RPS6KA1,PML,APP,BIRC2,SAP30L,ARID4A,MXD1,HDAC2,SAP30 |
| 1.829e-05 | -10.91 | Regulation of TP53 Activity through Phosphorylation | REACTOME pathways | R-HSA-6804756 | 93 | 32 | 10287 | 1696 |
PRKAB1,TP53RK,PRKAA1,TPX2,RMI2,CSNK2A1,BLM,MAPK14,RMI1,CDK5,RPA2,MDM2,CCNA2,PIN1,NOC2L,PLK3,RFC3,TOP3A,BRCA1,AURKB,RFC2,SUPT16H,RPA1,TAF2,RPS27A,HIPK2,STK11,TAF12,CHEK2,TAF6,CDK2,SSRP1 |
| 1.832e-05 | -10.91 | GO_GENERATION_OF_PRECURSOR_METABOLITES_AND_ENERGY | MSigDB lists | GO_GENERATION_OF_PRECURSOR_METABOLITES_AND_ENERGY | 275 | 68 | 17377 | 2626 |
NDUFA5,COX15,NDUFB6,UGP2,SUCLG1,GNPDA1,NDUFAF2,MDH2,UQCR10,ADPGK,GYG1,SDHA,EPM2A,CALM2,NRF1,IL6ST,CS,SUCLG2,NDUFB9,AKT2,IDH3A,PFKFB3,NDUFA7,OGDH,NDUFB1,POLG2,TAZ,RPS27A,NDUFA11,DHTKD1,COX5A,UQCRH,PFKP,COX5B,NDUFV2,GALK1,NDUFS1,PPP1R2,MECP2,SLC25A12,COX4I1,CYCS,NDUFA4,NDUFS7,NDUFS4,PPP1R3B,FASTKD3,NDUFV1,NDUFA2,NDUFB4,MSH2,NDUFS8,CYC1,NDUFA3,PHKG2,LDHA,TBRG4,GNAS,CAT,SDHB,ACOX1,COX7A2L,COX8A,MDH1,NDUFS5,GPI,IDH3B,PGAM1 |
| 1.834e-05 | -10.91 | SNRPB (small nuclear ribonucleoprotein polypeptides B and B1) | protein interactions | 6628 | 124 | 39 | 17029 | 2761 |
CTDP1,DHX9,CUL1,SNRPD3,RPA2,SNUPN,EIF4A3,HUWE1,EFTUD2,GEMIN6,SS18L1,GEMIN4,STRAP,SRPK2,SNRNP200,SNRPB,CUL3,LSM8,DDX20,PRPF3,SF3A2,CLNS1A,RPA1,CAND1,GEMIN5,UPF1,GOLGA2,L3MBTL3,CEP55,PRMT7,SNRPG,SNRNP70,SMURF1,CD81,COIL,CDKN2A,SMNDC1,GEMIN7,PRPF4B |
| 1.834e-05 | -10.91 | TCTN1 (tectonic family member 1) | protein interactions | 79600 | 124 | 39 | 17029 | 2761 |
PPIB,DDX47,PRKCSH,TOR1AIP1,MOGS,NENF,SDF2L1,CLCC1,FKBP2,IKBIP,POFUT1,GNB2,BCAP31,NUP205,SEC11A,RPN1,NUP210,DNM2,RPN2,MINPP1,LMAN1,PDIA6,CNPY3,TMX1,TMED2,MLEC,ERO1A,DNAJC10,TTC13,TXNDC16,MAGT1,DDOST,TMED10,PRPS2,SEL1L,SIL1,NCLN,SPCS3,CHID1 |
| 1.834e-05 | -10.91 | NOLC1 (nucleolar and coiled-body phosphoprotein 1) | protein interactions | 9221 | 124 | 39 | 17029 | 2761 |
COX15,NOP2,SUZ12,RPL15,KLC1,CSNK2A1,BRIX1,PRKACA,APP,PIP4K2A,RPL11,RPL23A,SUB1,DDX56,MDM2,RPL19,POLR1B,FBL,SRPK2,CDC5L,POLK,RPL6,EZR,BRCA1,MCM2,KIF11,CDK11A,DHX15,TWISTNB,MFAP1,E2F4,RPS14,YWHAZ,CHMP4B,TCOF1,RRS1,ARRB2,COIL,SSRP1 |
| 1.834e-05 | -10.91 | HNRNPUL1 (heterogeneous nuclear ribonucleoprotein U like 1) | protein interactions | 11100 | 124 | 39 | 17029 | 2761 |
ZNF207,COX15,CYLD,EWSR1,RAB11B,IVNS1ABP,RAE1,HNRNPUL2,CUL1,SAFB2,RBM4,GIT2,WWP2,TMEM179B,RPA2,BRD7,TARDBP,TP53BP2,TMED2,HNRNPF,CUL3,BRCA1,MCM2,PRMT2,MATR3,SF3A2,ECH1,RPA1,CAND1,PDCD6,PCM1,SYNCRIP,DGCR8,SAFB,RBMX,HNRNPH3,COPS6,CFAP20,HNRNPDL |
| 1.836e-05 | -10.91 | cerebral_cortex | COSMIC cancer mutations | cerebral_cortex | 19 | 11 | 17385 | 2587 |
TSC1,NRAS,TSC2,PTEN,MSH2,USP32,KRAS,H3F3A,HRAS,MSH6,CDKN2A |
| 1.838e-05 | -10.90 | protein localization to endoplasmic reticulum | biological process | GO:0070972 | 127 | 38 | 17256 | 2622 |
RPS15,RPS2,RPLP2,SEC61G,RPL15,SEC16A,BCAP31,RPL23A,RPL11,RPL17,RPL19,ANKRD13C,BCAP29,KDELR1,SRP72,RPL29,SEC61B,RPL35,RPL6,RPL8,RPL38,RPS10,RPS24,RPL27A,RPS9,RPSA,RPL36,RPL37,CHMP4A,RPL32,SEC61A1,RPS27A,RPS14,RPLP1,MIA2,CHMP4B,SPCS3,RPS26 |
| 1.838e-05 | -10.90 | mitochondrial membrane organization | biological process | GO:0007006 | 127 | 38 | 17256 | 2622 |
TOMM20,IMMT,DYNLL1,BCL2L1,ATP5F1B,ATP5PF,MOAP1,BCL2,TP53BP2,APOOL,ATF2,STAT3,TIMM50,PPIF,BAK1,ATP5IF1,HEBP2,ATP5MF,RHOT1,SLC25A5,TAZ,RHOT2,CHCHD6,MFN2,CHCHD3,HSPA4,TIMM13,ATP5MC3,TIMM29,TFDP1,PPP3R1,E2F1,YWHAZ,ATP5F1A,TFDP2,YWHAH,TMEM14A,EYA2 |
| 1.853e-05 | -10.90 | NSFL1C (NSFL1 cofactor) | protein interactions | 55968 | 82 | 29 | 17029 | 2761 |
CCT2,PPP1R2,NF1,UBXN1,LACTB,TUFM,CUL3,CUL1,NUF2,PDXDC1,DHX15,NPLOC4,CAPN2,PSMD2,UBXN2A,IDE,PLAA,ATIC,DBI,FBXO7,UBA5,VCPIP1,ANP32A,TARDBP,AHCY,TATDN1,NGLY1,PSMC1,FAF1 |
| 1.854e-05 | -10.90 | ovary-other-neoplasm | COSMIC cancer mutations | ovary-other-neoplasm | 13098 | 2032 | 17385 | 2587 |
HECA,ZBTB10,TSC2,ABCC10,HEXB,LACTB2,CCNL2,CMTM6,ANKRD39,FBXO22,RPL23A,EEF2K,CDKN2C,NAPG,USF1,THAP4,RAD23B,ATP13A3,MECR,AP1M1,DNM2,UPRT,ECD,LRRC59,TIPARP,MGAT5,RHBDD2,FTSJ3,USP34,BAK1,CCDC57,ERCC1,ZNF559,RHOBTB3,NRAS,GABPA,KIF15,WDHD1,MIER2,NUTF2,DIDO1,RAB22A,GINS4,ARF4,KRIT1,BOLA3,AHNAK,SMAD2,MID1IP1,RAD18,PDRG1,RPS27A,MYO18A,MPV17,COX5A,RNASEL,SMAD1,CHPF2,OAZ1,ANXA11,SMNDC1,PDCD4,SLC25A33,ZNF720,NXT2,HIVEP3,CLSPN,KIAA0100,GGA1,RHOC,MUM1,CCZ1,TRIO,DHX9,RAB23,KCTD17,HAUS4,EIF2AK4,PDCD7,APH1B,PSMD9,PARN,CDC73,HAUS2,MYL6B,COPB2,ATG4A,TMEM179B,CD59,TFAP4,SMC3,C4orf3,MEGF8,RIMS3,FBXO7,EFTUD2,MRPL21,NUP85,PABPC1,NSUN4,PPA1,LUC7L2,EIF3L,IFRD1,AGGF1,FOXK1,RBM42,MTA2,TYW1,GTPBP4,SSR2,ITM2A,USP10,MAP7D1,MRPL16,ELK1,EIF4H,SFXN5,RDH11,FNTA,KPNA1,TXNDC16,PDLIM1,ETS2,TYW5,WIPI2,TMEM159,ZNF830,RUFY3,PDLIM5,ACSF2,MRPL3,ALS2,EXOC3,TRIM41,NQO1,POC1A,ANK3,VTI1A,TPX2,TBC1D13,SLC35B2,INO80E,LCLAT1,STMN1,GLRX3,CBWD5,CPNE3,REPS1,KIAA1147,ABHD16A,RBM23,FBXL6,ZNF420,AHCTF1,TBC1D22A,SH3BP1,MTA1,UBA5,NSFL1C,CLCN6,SEPT11,INTS12,GPD1L,ZC3H3,RPRD1B,ARL5A,PDCL3,SNX8,CPNE1,SEC61B,ERMP1,FAM118B,GOPC,IDH3A,CRNKL1,POLR2D,E2F3,PFKFB3,GORAB,MEF2D,GSTCD,TANC1,RAB1A,MAT2A,GIGYF1,TMEM184C,KIF2A,PPP2CA,LSM6,VPS26B,NSMCE2,CORO1C,CAMKMT,RNF38,DMWD,SNRPG,PPP5C,PITRM1,TUBB,USP13,COMMD10,MZT1,ZNF445,ZFP91,HABP4,TRMT6,CCM2,FLOT1,BTN3A1,ATG2B,IP6K2,WDR5,IFT27,PMVK,SLC25A43,RRP36,NEIL2,SRXN1,GOLM1,RPA2,PSMD2,PDCD10,CLIC4,ITGB8,COQ4,CBWD2,HUWE1,ARF5,ARHGEF1,NAA50,ANXA5,LTN1,UBE3B,NAP1L4,ZNF710,ST8SIA2,GTF2H2,FBXL19,TTPAL,STAU1,TCTEX1D2,DDX24,TACC1,MRS2,LDHA,HEBP2,LLPH,C14orf132,RAB3IP,TTC33,PICALM,UTP20,SH3BP5,SLC19A1,MAGT1,ACOX1,FAM3C,AEN,CD81,PARP10,YWHAH,TMEM131,WDR13,FAM129A,TRIM11,YTHDC2,SNX15,NENF,SND1,TRIM65,FANCI,PAPOLA,ZER1,KRR1,CREM,FANCL,TET3,RAB8A,NUP210,GLIS2,NT5DC1,INTS1,IL6ST,SLC44A1,POP7,NOC2L,MTPN,TACC3,RYBP,VPS13B,PLK1,PTPN18,CELSR2,SEPT9,MIOS,RBX1,APH1A,SNRPB,MBLAC2,CKAP2L,CDC6,IL12RB1,EAF2,KRTCAP2,ODC1,USP21,LSG1,ALG3,TRIM4,TRAM2,FBXO28,AGPAT2,CHD3,ZNF367,ARRDC1,ADAM9,KPNA2,PRPF4,DVL1,CLN3,BEND6,FAM208A,NGLY1,POT1,NUMB,ZNF564,C1orf74,RMND5A,PARP12,HJURP,DNAJB2,CENPF,NKD2,LAMTOR3,SDC2,CHCHD2,COX4I1,ADCK5,CDK13,RAB6A,DNAJB1,NCKAP1,LYRM2,TNS3,SUB1,C1GALT1,UBE2Q2,CCP110,RINL,MBD2,ZNF746,XPA,ARL6IP1,CTR9,AHCY,GLE1,LRSAM1,HDHD2,NIPSNAP1,NTPCR,ABHD2,DCAF8,NSDHL,AMD1,CAMSAP1,MAP4K3,METTL22,STYXL1,APPL1,RBM38,NMT2,HAUS8,RXRB,SDHB,MBIP,PCM1,GALNT2,TMEM168,ORMDL2,COX7A2L,NLRC5,SIL1,DTD1,MYO9A,BTBD10,CCNB2,UNC13C,USP7,SART1,TRAF7,RPLP2,SUCLG1,ARID2,NDUFAF2,TMX4,TOR1AIP1,SLC2A1,LAGE3,TM9SF3,ZFYVE21,RRAGC,ATP6V1B2,PCBP1,LYN,VAV1,OIP5,TMEM69,MRPL50,NRF1,PSMA6,ZNF473,BRPF3,WDR44,PPME1,EFCAB11,RPAP1,TARDBP,BCAP29,CABLES2,TOP1MT,AHCYL1,LMAN1,STRAP,CTDSP2,ZNF583,PRPF19,SNX25,KDM3B,MND1,CLCN3,BIRC3,POLR2G,ZNF780B,PPT1,RAB7A,ANKRD33B,PPIE,NUP155,CHMP2B,VDAC1,MRPS14,EIF3H,RHBDF2,GLOD4,SUGP1,IDE,DHX16,RBL1,STK38,UBXN2B,FASTK,UHRF2,AP1S1,CHMP4B,XRCC3,H3F3A,CHID1,SMAD4,PARD3,BCL2L12,SLC30A9,NADSYN1,CMAS,C19orf53,KLHL21,PDAP1,TMX3,CDCA8,HMGN3,SLC12A9,NCAPG,SCYL2,TUBGCP2,FZD6,HERC3,HOMER1,CTSS,WBP1L,POLR1B,ORC3,RNLS,YTHDC1,ACP2,RHOA,RPRD1A,CSRP1,HMGN5,BTAF1,ABCF2,TOP3A,ARHGEF12,RANGAP1,PNPLA8,PCGF1,ZFR,DDX23,RAB18,ATP6V1D,SEC23IP,L3MBTL3,NEIL3,CTBS,BBX,E2F1,USP20,IMPDH1,TMEM219,RBPJ,TAF12,NR2F2,HIPK3,IFI16,NUP188,TXN,MAX,H2AFZ,PNISR,PDCD6IP,GXYLT1,LUZP1,PRKCSH,ADAM10,TSC22D3,CXXC1,AP3M2,CUL1,USP39,NANS,GYG1,OAT,UBE2I,MYEF2,SLC25A37,ASPHD2,ANKRD26,NOL11,FIZ1,RAB4A,ZNF200,TRA2B,CISD2,SLC26A2,ZNF800,CDC5L,SRP72,SGCE,OSBP2,KLF10,NSUN2,LACTB,USP22,CBFB,RFC2,RAB2B,CLNS1A,EIF3A,PRIM1,ZMYM3,DOT1L,IWS1,MAP3K4,ANKRD10,HHEX,WAS,KIF18B,TPP2,LUC7L3,MAP4,BTF3,PTPDC1,ZMAT3,NMD3,PRPF38B,RECQL,C9orf78,DNAJC5,EWSR1,SCOC,PRKAA1,VAV2,C16orf87,ANKH,RRM1,DLGAP4,ACAP1,TATDN3,B4GALT1,PXMP2,SUPT7L,ZNF79,PSEN1,TMEM165,PDXDC1,VPS25,NDUFS7,CNOT3,NPLOC4,YY1AP1,SPAG5,WDR48,RTKN,C12orf10,FAM192A,RPN1,CEP104,EXOSC7,LHX8,KLHL5,ARPC5,ZNRF2,MSH2,PIGG,TPST1,FBXL7,OSTF1,CYC1,PIK3IP1,FAM171A1,APOL1,FDFT1,SOCS5,GCC2,PIGT,PRIM2,ELL2,EMB,RDH10,MFNG,ZNF574,C1orf35,GORASP2,EXOSC9,ARID1A,CAPZA2,ADRB2,FXR1,C9orf40,PTTG1IP,GOSR1,MAP2K2,CCT8,MTR,AKAP1,PI4K2A,HMGN2,XRCC5,DERL1,CAT,SLCO4A1,HSPBP1,TTC13,GOLGA2,MED15,PIAS2,FAM83D,USP32,APPL2,ARAP1,CABIN1,SAMD8,SMPD4,GPI,CDKN2A,NUDT3,CYTIP,ATXN3,RAB11B,RAF1,UROD,KIAA0232,SLC39A13,BCL2L1,CD320,EPM2A,NUDT19,DECR1,CCNA2,MTMR4,RALB,LPIN2,ADCY9,SOCS6,MRPS27,BRI3,TTC3,TP53BP2,RNASEH2A,AQR,ILKAP,CDK12,SAP30,ANKLE2,BRD4,CDC123,NARF,LRRC8A,ELP4,ABHD11,EDF1,PKMYT1,ASB13,ERC1,TRIM28,SUPT16H,EIF3K,ANKZF1,ZNF282,RAD51C,CHMP4A,HINT1,DDOST,DSN1,SAFB,LMBR1,RWDD4,CBWD1,ATF6,NCLN,BEND3,EYA2,DYNC1LI2,PRPF4B,ADAM23,NDUFS1,SLC41A1,B4GALT5,MECP2,MANBA,TKT,CBLL1,ARGLU1,SECISBP2,LANCL1,POFUT1,FAM8A1,HEATR5B,WWP2,SLC25A36,JAKMIP1,EBP,RFWD3,CCNK,DNAJC8,FUT8,FJX1,AXIN2,PTPN11,BTF3L4,FEM1B,CNN2,NDUFA3,MTX2,MSH6,JMJD4,KAT2A,LONRF3,RFXANK,RABIF,FBXO9,PACS1,BMS1,KCNQ1,OTUD3,ARSK,MACF1,KIF11,KLF6,SMAP2,FADD,MYO1F,CBX3,TMEM127,PPP1R11,NDUFS5,WDR62,WDR91,TAF6,ESPL1,DDB1,DEF6,FAM83G,IPO4,POLA2,UBL3,PIGM,NAT9,ZNF76,LYRM4,MTX3,HMGXB3,PHRF1,UBE2Q1,ABCB10,BRIX1,MAP1LC3B,MRPL19,SF3B2,PCYOX1L,DST,CDC42,SYNM,GOT2,SIVA1,RAB35,JAZF1,HADHB,RPF2,GPATCH1,TCEA1,SLC35C2,CNNM3,CARM1,SRPK2,WDR41,LARS,DEAF1,ZCCHC10,SNRNP200,CCDC138,NCK1,LAP3,VHL,LRBA,TMEM216,ARHGDIB,PITPNB,KMT2C,OGFR,PRPSAP1,ASF1B,RPL37,MAN2A2,HSPB11,EIF4ENIF1,BRWD1,NIP7,U2SURP,PPM1G,SH3GLB2,MIA2,BAZ1B,ZNF268,STK11,CHEK2,CLU,VPS4A,ZSWIM3,CHPT1,MRPL13,TSTD2,ATP6V0E1,DCAF5,CAPN1,UBE2D3,NSMCE4A,PPP1R2,PPP1R12A,GORASP1,ZCCHC8,EPN1,PCSK7,THRAP3,PM20D2,XPNPEP3,RGS2,TTF1,QSOX2,PRPF18,NUP205,CHKA,LYAR,DTL,MED10,ZRANB1,SLC12A2,ATP6V0D1,CSNK1G3,POLR2I,TRAFD1,CREG1,NUDT4,SUGP2,GBA,EIF2A,VKORC1,CCDC71L,SLTM,ARHGAP15,EVC2,MASTL,UAP1,KLHL15,NFIL3,SIAH2,FN3KRP,SLC16A1,YWHAZ,CTSA,SNRNP70,EHD4,TMEM14A,TSEN15,ADNP2,TCF12,CHMP2A,PRKAB1,FEZ2,CORO7,MDH2,UCK2,PMS2,SMARCA4,ORC1,EXT2,MXD1,USP5,HNRNPA2B1,RRN3,UBXN2A,IARS,NVL,KIF14,CS,CYB5R1,CLTB,EBAG9,CSTF1,POU2AF1,UBQLN4,NXT1,PGGT1B,RNF25,SMU1,PCGF6,ATXN1,GLO1,OGDH,BICD2,CADM1,EDEM2,HERPUD2,TOLLIP,FANCE,MBD3,PDHX,ALKBH6,PON2,SURF4,DUS3L,HNRNPR,HPS5,STAT6,ARNTL,ANP32E,FKBP5,CCDC125,MAPK1,ABCA1,PDCD2L,TMEM33,DNAJC2,GCLM,TRIP12,RAE1,SCYL1,NUP54,VPS45,CHIC2,PAWR,MYO9B,MXD4,DCUN1D4,PIP4K2A,GFM2,XPR1,FERMT3,SPPL2A,KIF5B,FASTKD3,FGFR3,MZT2A,KLHL20,SEC24C,PPIG,RRBP1,ZDHHC13,H2AFY,ARHGEF2,ANP32A,ATG13,LDLRAD3,FBL,ERI3,C12orf75,STAT3,FRMD8,SLC35A1,MYO5A,NIPAL3,TGFB1,TXNL1,ELOVL5,HEMK1,FAM49B,TMEM39A,PSPC1,HELB,SCFD2,RFFL,COG1,RCOR1,PRMT2,NDRG3,CDK11A,TFEB,LEMD2,SERF1B,UPF1,ELMO1,ZC3H7B,DTX4,ACAT1,MEGF9,CENPT,ZMIZ1,PLOD3,TERF1,HRAS,RAB3IL1,ZSWIM6,CCDC93,RAB14,FGFR1OP,TMED7,ADD1,MRPS15,KDM4A,XIAP,DHX8,GLUD1,CNTROB,PPP1R16B,ANKRD23,CALM2,CDK5,PSMD1,NSRP1,RABGAP1L,SRSF4,PDS5B,FNIP2,NUP153,SENP1,PCBP2,KCNAB2,PLK3,PGAP2,TMEM115,PLEKHM3,MCL1,DCUN1D5,PPFIA3,ICMT,PWWP2B,TRIM47,WDR11,AXIN1,LIMK1,ZNF689,PRDX5,MLYCD,ATP6V0C,ST3GAL2,SMG9,FBXL3,E2F2,LONP2,PFKP,AAAS,SSRP1,DDX42,NDUFV2,MRPS2,CERK,TOP2B,SLC4A2,EZH1,ITGB5,LMNA,RAVER2,DDRGK1,GNS,DDX56,EIF2S2,INPP5A,INTS7,MCM5,PHF14,ZNF326,FOXN2,UBE2QL1,CARS2,NAGPA,PRRC2A,C16orf72,RB1CC1,PGS1,DHX29,MAN1B1,TEX10,RPS10,MYBL2,UHRF1BP1,CBFA2T2,MPG,MATR3,ABCF1,CYB5A,RHOB,PTPRF,DTWD1,SCARB2,OSBPL11,CCDC86,DUSP3,SETD3,TEX30,PTAR1,CNOT6,NDE1,HEXA,SNX14,RNF139,EGLN1,ZNF207,ANKRD27,PPP1R37,ABCA3,SARNP,TRERF1,IVNS1ABP,UBR2,ACTR3,CHD1L,WDTC1,MYH9,CREBL2,NIPA2,NIT2,NUF2,ZNF267,PRKACA,SAFB2,TMEM161B,KTN1,APP,ANKIB1,STAM,ARL6IP6,RAB21,PRKD3,CLUAP1,ATP2A2,ZKSCAN1,UTP18,GRSF1,ZCCHC2,DDA1,NUP107,ANKRD13C,RNF19A,CEP63,MAVS,FAM76B,RBM15,CLN6,ATF2,TMEM9,GCC1,RNF169,DCTN1,ADCY7,ATP6V1G1,SHOC2,MAP4K4,RNPS1,WBP2,ATP6V0A1,CDCA2,NUSAP1,DNAJA1,NDUFA7,GPR137,DDX17,CHCHD3,TAF2,CDC16,SEC61A1,HIPK2,WDR7,CBLN2,MBOAT1,FUS,PDXK,ZBTB11,COIL,LRP8,LRCH1,ZNF786,GALK1,ANXA6,TMBIM4,SESTD1,TRAK1,GMCL1,AKT1S1,UBE4A,IL21R,ETS1,WRB,ZNF92,PNO1,KRI1,CAPN2,FBXO3,ERH,ADD3,GATC,NDUFB4,PPP1R8,PRDM4,DCP1A,TTLL12,SGCB,TMX1,IMPA2,HNRNPM,MFSD12,NUDC,LDHB,PDPK1,PPP3CA,TK1,TNFAIP3,POLK,GALC,ZNF512,KIAA0930,EMP3,MRPS10,MTMR12,PDE3B,DDX39A,RPA1,ZNF180,ZNF862,KIF18A,KEAP1,CCDC6,WNT5B,TATDN2,PITX1,MAPK6,CAPN7,PML,LRPPRC,C4orf46,LY75,SLC25A19,HMGB2,RGL1,PSAP,WDR76,USF2,IGBP1,FAF1,ANAPC4,SNAPIN,SRM,COX15,DDX47,AGRN,THOC1,GNPDA1,GPBP1L1,PPP1R15B,MCCC1,CSNK2A1,CDC42SE2,S1PR2,CDIPT,SEC16A,GIT2,BIRC2,ATPAF1,SSR1,LIN9,DLG5,ABL2,PCNA,ZNF639,TRMU,PIK3R2,XRCC2,ETV6,PPCDC,TXLNA,ZFYVE27,MYBL1,MCMBP,CCAR1,PTPRK,CDC37,ABCC5,METTL1,PBXIP1,TLK1,MRPL12,LNX2,EZR,LRP5,BRCA1,PRKRA,ANLN,STX16,RAB5B,RHEB,DPYSL3,OPTN,SEPT1,TBC1D17,TONSL,SOCS4,QRSL1,PIEZO1,OSGEPL1,ZNF45,NUDT11,GLCCI1,NAA60,SEPHS2,LZTR1,CTCF,ASAH1,RACGAP1,PPP3CB,B4GALT4,DOCK11,RLF,CRLF3,RAPGEF6,LRRC14,SNRNP25,RB1,NUS1,VASP,VMP1,MEA1,TIMELESS,SLC27A4,MDFIC,MAML1,TMEM8A,ALDH18A1,ABCC1,PREB,TRAPPC9,AACS,NQO2,MEMO1,UTP15,EIF2AK1,KRAS,NFATC2IP,UBE4B,ARPC1A,EIF4G2,ZDHHC3,ZNF174,MOSPD3,GOLGA4,ITPRIPL1,CDC27,SYNCRIP,PALB2,SNAP23,PRPS2,TBPL1,PRMT7,NIPA1,RNF114,KCTD7,NDUFA5,CYLD,UGP2,FOXM1,XAB2,MRPL39,SUMO2,COPE,DUSP22,COMMD8,RPAIN,RAD23A,RPL11,ATP6V0B,PDK2,MDM2,STRBP,DUS4L,CORO1A,METTL9,MINPP1,DVL2,GM2A,SLC39A9,CLPTM1,PSMA8,COQ10B,CPOX,CYP20A1,SLC26A6,DNAJC9,MTMR6,NFATC2,PRPF3,KDM1B,TXNL4A,ARL5B,RPSA,USP36,CCDC127,SRSF1,DNAJC10,MRPL2,ATP1A1,SCAP,ZNF700,TOMM6,TIMM17A,PSMD3,CEP55,DNAJC17,ZNF436,NCOA1,LTA4H,USP53,AP2S1,ZC3HC1,ATXN7L2,INTS2,CTDP1,MIF4GD,CDC40,GOLIM4,RRP15,DAP,GNE,ARID5A,SMC6,ARFIP2,SUMF1,NKRF,GGA2,AP3S1,CSNK1A1,RMI1,BZW2,TFRC,WRNIP1,PTPN2,IRF4,SLC1A4,CWC27,TMA7,SLC35B4,ABCD1,SS18L1,DDX31,CENPM,PTGES3,RPAP3,MLEC,SNX2,ZNF202,ZMYM5,CCDC34,PPWD1,CHCHD6,BSDC1,NEU1,TPD52L2,KPNA4,FBXO41,GOLGA7,BIRC5,TWSG1,SNAP29,TFE3,CDCA7L,GLG1,PGRMC1,FAM126A,PKD2,CHMP7,RPS6KC1,SAT2,GCSH,ZNF496,NDUFB6,TMEM41B,ZDHHC8,TAP1,TMEM109,YTHDF3,NHLRC3,PLXNA1,IKBIP,SLC20A1,COMMD6,ABHD14A,ELMOD2,KIFC1,ASAP2,SNUPN,DBNDD1,CYB5RL,PARPBP,CNPY4,CDC25B,PRADC1,PLCL2,TFG,DNMT1,SEH1L,NOL12,ORAI2,ATG9A,AKT2,PBK,NOL8,GNG7,MKI67,DDX20,SLC17A5,GALNT7,AURKB,MCFD2,CCNF,FOXRED1,ZFAND5,SLC25A5,MAK16,RBM47,STT3A,TMED10,PTER,WDR4,EIF2D,ITGB1,DHTKD1,UQCRH,TRAF5,ARRB2,RTN3,ZNF598,HDAC2,DDX58,WSB2,PWWP2A,PPIB,HSPH1,MAPRE1,GMFG,MUT,HLA-E,KIF23,NDUFA4,SLC35B1,NOTCH2,PMF1,MAN2B1,METTL3,NDUFS4,CFLAR,FKBP1A,RNF121,SLC31A1,MEX3C,KLF16,SNX18,DAD1,ATIC,BDH1,CTPS1,ATP6V0A2,PCYT2,PIKFYVE,RNF135,GNAI2,LPCAT1,ANKHD1,EEF1D,TMED2,MORC3,TERF2,PIP4K2C,KCTD20,SEPT8,DCTD,FAM133B,RIT1,PLEC,TOMM40,KDM3A,FAS,ADSS,EPRS,ZNF777,SERF2,ZFP92,NSF,QARS,DCK,ERGIC3,ACLY,LPCAT4,VCPIP1,TCOF1,YY1,PPP6R2,MAP3K5,RNF14,CDK2,CABLES1,NRBP1,ZC3HAV1,DNMT3A,RWDD1,SYS1,TRIP10,ZBTB37,URB2,SF3B1,CAST,SUZ12,RPS6KA1,MAGED1,RAC1,GPR89A,EIF3D,OLA1,KLHL18,ADPGK,AP1B1,SLC25A44,SDHA,GNB2,PHC2,FLAD1,CRKL,TERF2IP,APLP2,ZNF75D,SHC1,KDM2A,UCHL5,TNPO2,CDKN1B,TALDO1,NAA35,CCT2,ATP13A1,MAPRE2,MKLN1,ERF,LYRM1,CUL3,SLBP,KIAA1586,GALK2,CDC23,AP4E1,H2AFV,SHCBP1,PSMB9,POLG2,DHX57,PRDM11,NSA2,VEZF1,HSPA4,PPP2R5A,JAK1,ACYP1,TBL3,PPA2,SEL1L,STAT1,KLHDC4,TRIM32,PDCD11,ATMIN,POLQ,RHEBL1,OTUD5,NCOR2,ANKRD13D,PKP4,SCAMP3,C1orf112,BABAM1,TCF3,CDCA3,BRAP,SLC25A12,MYNN,AGPAT3,BLM,SPR,FOXO3,REEP5,RAB11A,CCDC28A,MAD2L2,TMCC3,GTF2F1,MAT2B,RBM17,PTEN,CRAT,AHSA1,CENPJ,PRC1,UPF2,COPS7B,SLC38A10,CREB1,OSTC,UBE2M,IFT46,PACS2,NCOA2,SMC4,TSHZ1,ZFP64,STRIP1,DENND4C,NEK7,WDR18,PARP4,ILF3,TBRG4,ANAPC2,LRRC1,RHOT1,MARK2,TSR2,ECH1,PRDX1,YIF1A,NUCB1,GNA12,FBXO21,SGSH,HGS,C1orf131,SLC38A7,PRDX3,TTLL4,PFDN4,HNRNPH3,MFAP1,TFDP1,STX18,CCDC69,ASNA1,BRWD3,SSSCA1,VPS29,BYSL,S100PBP,ESYT2,MIB2,PTMS,UBE2E2,SKA3,NPHP4,ST13,TMEM184B,NOP2,HNRNPAB,PLXNC1,UBN1,DCAF15,NF1,ALKBH5,DNAJC24,ZNF107,UBE2Z,TAF6L,AGFG1,SIRT2,KIF2C,FKBP2,USP48,SNRPD3,UBQLN2,MAPK14,BECN1,CUTC,SNAPC4,RNF103,EDC3,BCAT2,UBLCP1,MBD4,ZNF804A,C18orf32,RAP1A,THADA,AP3S2,METTL14,DPYSL2,ATG3,ZNHIT6,IMPAD1,RCSD1,PHTF1,SRI,PPP1R12C,AKR1B1,NDUFB9,JOSD1,RP2,NFU1,TTC4,TECR,OGG1,ARID4A,TRIM14,FGFR1OP2,TIMM50,COPS8,FYTTD1,TDP1,TRIM8,DPM1,FOPNL,SLC16A7,STK17B,DHX15,ABHD5,CHAF1A,UBTF,CXXC4,GEMIN5,PAF1,PQBP1,IARS2,GALNT10,COPS6,SASS6,PSMC1,STARD3NL,SLC12A7,RPS15,TBC1D12,PIGN,AGTRAP,CIB1,TIA1,MED13L,MEF2A,EPHX2,SRRT,PITHD1,RHBDD1,ZNF449,ZNF335,BUD31,CAPZA1,GLTP,YBX1,KIFAP3,BCL2,KNTC1,ACAD8,UBE3C,N4BP2,KDELR1,HP1BP3,VOPP1,TSTA3,CIC,OXR1,THNSL1,SEPT7,CAND1,GNAS,TSC1,NAP1L1,RBM25,ODF2,EXOC4,KIAA1328,PITPNA,ZFP90,NUP62,NAA20,RBBP4,PDSS2,PTDSS1,C7orf26,ZBTB24,SMARCD1,TMEM106C,MBD1,WASF2,MMACHC,TOMM20,ASH1L,IMMT,GNPNAT1,MPHOSPH8,CHERP,WDYHV1,HNRNPUL2,PLAGL2,IRF3,TWF2,CHD1,MEAF6,PAIP1,ANKRD28,ANKLE1,FARSA,CCDC50,SAR1A,AKAP8,PARL,RPN2,APOOL,CHTOP,PDIA6,F2R,FAM3A,ABI1,HTRA2,MOSPD1,RLIM,ACSL5,FAM172A,PSMB7,NLN,WIPF1,TOR1AIP2,BUD13,AZI2,NDUFB1,PEF1,BTBD1,RAD54B,TMEM41A,DAP3,ZNF317,TAB2,TULP3,GADD45B,WDR59,SCARB1,GAS2,USP11,AKNA,SMURF1,TSPAN5,CBX4,KIF3B,CDS2,GOLPH3L,SH2D3A,CASP6,EYA1,TOR3A,SRGN,MRPS26,DBF4,LETMD1,KLF13,RGS1,HDDC2,MAN1A1,FBXO5,GART,CTNNBL1,TANK,PELO,BRD7,TTC17,SLC25A1,SAMD4B,PAQR6,GINS1,ZDHHC18,GTF3C6,TELO2,CSNK1G2,ADAM17,HMGN1,NASP,ASPM,PPP1R21,PRKAR1B,POLR3GL,MEN1,ZNF407,SYMPK,TARS,SNRPA,MFN2,MAPK3,ATAD2,OSBPL8,ZNF330,COX8A,MBD6,SRSF3,IDH3B,PREPL,TATDN1,ATP6V1C1 |
| 1.855e-05 | -10.90 | vesicle targeting, to, from or within Golgi | biological process | GO:0048199 | 70 | 25 | 17256 | 2622 |
USO1,TRAPPC9,GORASP1,CUL3,MCFD2,RAB1A,PEF1,SEC16A,ANKRD28,CD59,SEC31A,SEC23IP,PDCD6,GOLGA2,NSF,TMED10,SEC24C,PPP6C,PPP6R3,TFG,LMAN1,PPP6R1,TMED2,CSNK1D,PREB |
| 1.864e-05 | -10.89 | RBBP7 (RB binding protein 7, chromatin remodeling factor) | protein interactions | 5931 | 155 | 46 | 17029 | 2761 |
PTMS,HJURP,SHPRH,SUZ12,SUMO2,HMG20A,PARK7,LIN9,SAP130,C12orf10,RB1,USF1,HUWE1,MTA1,MBD2,BANF1,SAP30L,ARID4A,CDC5L,SAP30,PHF20L1,NASP,FOXK1,TSTA3,VHL,MTA2,WDR1,TOPORS,BRCA1,EAF2,MBD3,APPL1,PHF6,ASF1B,C1orf122,ADSS,BRMS1,CHMP4A,CHD3,DCK,APPL2,RBBP4,SINHCAF,TAF6,DDB1,HDAC2 |
| 1.864e-05 | -10.89 | DANG_MYC_TARGETS_UP | MSigDB lists | DANG_MYC_TARGETS_UP | 137 | 40 | 17377 | 2626 |
SRM,CCNC,TXN,H2AFZ,XIAP,SNRPD3,CCNB1,TFRC,HNRNPA2B1,PA2G4,PCNA,MSH2,UPRT,RPL19,IMPA2,METTL1,NRAS,TK1,SNRPB,LDHA,E2F3,PSMG1,NUP155,RPL27A,ODC1,RFC2,MAT2A,SRSF1,CBX3,AKAP1,NAP1L1,HSPA4,RPL32,PRDX3,PRPS2,DBI,E2F1,DDX5,LTA4H,UBE2C |
| 1.865e-05 | -10.89 | RPF2 (ribosome production factor 2 homolog) | protein interactions | 84154 | 74 | 27 | 17029 | 2761 |
NIFK,NOP2,RRP15,AATF,DDX24,MECP2,RPL8,GTPBP4,KRAS,EBNA1BP2,MAK16,RBM4,APP,DHX15,LMNA,KRR1,NSA2,DDX56,DGCR8,RPS14,RBM34,NOC2L,RRS1,ZC3H3,FTSJ3,IFI16,GPATCH4 |
| 1.882e-05 | -10.88 | PROVENZANI_METASTASIS_UP | MSigDB lists | PROVENZANI_METASTASIS_UP | 180 | 49 | 17377 | 2626 |
TCF12,KARS,TOR3A,TCF3,MAGED1,MON1B,CTCF,DAZAP2,TERF2IP,CDKN2C,TNS3,SAR1A,GOT2,TIMM23,MRPS27,BRD7,AKR1B1,ATP6V0D1,PPA1,TMED2,TERF2,SGCE,ZMYND11,HNRNPF,MFNG,NARF,DNAJC9,GALNT7,CBFB,BORA,TARS,POLR2A,PRIM1,XRCC5,CAT,EPRS,RBM47,NIP7,WDR59,GLG1,BTF3,VPS4A,RGL1,TRAF5,LTA4H,ATMIN,CDKN2A,TUBB,GCSH |
| 1.882e-05 | -10.88 | GSE15330_LYMPHOID_MULTIPOTENT_VS_GRANULOCYTE_MONOCYTE_PROGENITOR_DN | MSigDB lists | GSE15330_LYMPHOID_MULTIPOTENT_VS_GRANULOCYTE_MONOCYTE_PROGENITOR_DN | 180 | 49 | 17377 | 2626 |
PPIB,RECQL,DCAF15,TOR3A,DCTN2,C16orf87,CUTA,LAMTOR3,USP39,AP3S1,LCLAT1,IFT27,BIRC2,SPAG5,FERMT3,MRPL50,USF1,MTMR4,RABGAP1L,RCSD1,CAPZA1,CDKN1B,GLTP,OSTF1,CLDND1,APOOL,RNF5,ACP2,NEK7,TMEM216,WIPF1,SEPT8,PLEC,TANC1,RAB22A,DHX57,CYB5A,GLOD4,FNTA,CDKN2AIPNL,ACYP1,COX5A,ATE1,SLAIN1,RNASEL,EHD4,RNF14,HRAS,STARD3NL |
| 1.882e-05 | -10.88 | GSE44649_NAIVE_VS_ACTIVATED_CD8_TCELL_DN | MSigDB lists | GSE44649_NAIVE_VS_ACTIVATED_CD8_TCELL_DN | 180 | 49 | 17377 | 2626 |
HECA,MZT1,WDYHV1,C1orf112,SHPRH,TMEM109,RRM1,TM9SF3,HAUS4,BLM,DCUN1D4,C12orf10,MRPL50,NUP210,NUS1,PTEN,RNFT1,DAPK1,NAA50,GEMIN6,PRADC1,MCPH1,IMPA2,RNLS,PPP3CA,KLF10,PSMA8,PBXIP1,FOPNL,TYW1,RCOR1,GLO1,BORA,EML4,SRSF1,AMZ2,CDKN2AIPNL,FNTA,ATAD2,TTC13,TFDP1,COX7A2L,RWDD4,MBOAT1,ANP32E,OSGEPL1,TERF1,PURA,HDAC2 |
| 1.884e-05 | -10.88 | DEAD | pfam domains | PF00270 | 67 | 24 | 17054 | 2545 |
DDX58,DDX28,RECQL,SNRNP200,DDX47,DDX24,DHX29,YTHDC2,DHX9,DDX20,BLM,DDX39A,DHX15,DHX57,DDX23,DDX17,DDX56,DHX16,EIF4A3,DDX31,DDX5,DDX42,POLQ,DDX52 |
| 1.885e-05 | -10.88 | Regulation of DNA replication | REACTOME pathways | R-HSA-69304 | 77 | 28 | 10287 | 1696 |
MCM10,PSMA8,CDT1,E2F3,PSMB7,PSMA1,CDC6,ORC1,MCM2,PSMD9,PSMB9,PSMB3,PSMC4,RB1,PSMD2,PSMD1,PSMA6,CCNA2,RPS27A,PSMD8,MCM5,PSMD3,E2F1,CDKN1B,ORC3,CDK2,E2F2,PSMC1 |
| 1.887e-05 | -10.88 | ACADM (acyl-CoA dehydrogenase medium chain) | protein interactions | 34 | 51 | 21 | 17029 | 2761 |
PRKCSH,IDH3A,LDHA,VDAC2,CUL3,ARF1,DNAJA1,VDAC1,ARF4,CAND1,RPN1,ATP1A1,DDOST,ARF5,AHSA1,USP20,SUCLG2,ACADM,TECR,STRAP,LDHB |
| 1.887e-05 | -10.88 | WBP4 (WW domain binding protein 4) | protein interactions | 11193 | 51 | 21 | 17029 | 2761 |
ZNF207,SART1,EWSR1,CHERP,PSPC1,SF3B1,SNRPB,WIPF1,PRPF3,SF3A2,SNRPA,DHX15,DDX23,WAS,LSM6,EFTUD2,DNM2,PRPF4,FUS,SNRNP70,PABPC1 |
| 1.887e-05 | -10.88 | BRD1 (bromodomain containing 1) | protein interactions | 23774 | 51 | 21 | 17029 | 2761 |
FEZ2,PHB2,KAT7,NSUN2,PBRM1,CNTROB,MRPS14,MEAF6,LYAR,KPNA1,CHD3,H2AFX,YWHAZ,SS18L1,KPNA2,NAP1L4,H3F3A,YWHAH,DNMT1,RPL22L1,IFI16 |
| 1.920e-05 | -10.86 | GSE13306_TREG_RA_VS_TCONV_RA_UP | MSigDB lists | GSE13306_TREG_RA_VS_TCONV_RA_UP | 185 | 50 | 17377 | 2626 |
H2AFZ,REPS2,ZBTB37,KIAA0232,ENSA,UBE2Z,ZNRF3,CDIPT,OAT,SLC12A9,C19orf48,C18orf32,SHC1,MED10,EFTUD2,PTPN11,ARHGEF2,BCL2,MDFIC,BCAP29,MAST2,F2R,SLC12A2,JMJD4,ERMP1,CELSR2,USP42,KCTD20,OGDH,DCUN1D5,SF3A2,TTC33,DOT1L,PRIM1,MASTL,STOML2,CXXC4,ALG3,IDE,RBM25,POLR2J,DDOST,PFDN4,DBI,MAP4,MDH1,WIPI2,ATP6V1C1,DNAJC30,DYNC1LI2 |
| 1.920e-05 | -10.86 | GSE41867_LCMV_ARMSTRONG_VS_CLONE13_DAY6_EFFECTOR_CD8_TCELL_DN | MSigDB lists | GSE41867_LCMV_ARMSTRONG_VS_CLONE13_DAY6_EFFECTOR_CD8_TCELL_DN | 185 | 50 | 17377 | 2626 |
GCLM,NSMCE4A,NUP188,MRPS2,TOR3A,LAGE3,POMP,EIF2AK4,WDR5,NUP205,NDUFS4,CFLAR,USP5,RAD23A,PCNA,CTR9,MRPL40,MVP,NUP85,SYTL3,MRPL32,CARM1,GINS1,NOL12,PPAN,TELO2,CCT2,IFRD1,GTF3C6,NXT1,TCTEX1D2,KAT2A,PPIE,GTPBP4,TMEM216,CIRBP,PRPF3,RHOT2,MAT2A,IRF5,XRCC5,DOT1L,ALG3,UPF1,PRDX3,GADD45B,TCOF1,ATP6V1C1,LRP8,FAF1 |
| 1.920e-05 | -10.86 | GSE17721_LPS_VS_POLYIC_6H_BMDC_UP | MSigDB lists | GSE17721_LPS_VS_POLYIC_6H_BMDC_UP | 185 | 50 | 17377 | 2626 |
TMED7,DNAJC2,TP53RK,PDCD6IP,RWDD1,HJURP,DHPS,STRN4,C19orf25,BRIX1,C2orf49,OAT,PABPC4,RRP36,GTF2F1,EEF2K,MOAP1,VASP,SHC1,TNFAIP8,ATP2A2,AP3S2,PHTF1,CS,PTPN11,SEPT11,TAGLN2,SGCB,LRRC59,ABCC1,ACSL5,TSHZ1,PPIF,MAPRE2,HMGN5,GABPA,TMEM39A,CAMSAP1,C1orf35,FAM133B,STK17B,MAK16,SEC23IP,GADD45B,PRDX5,ACLY,TBPL1,SPRYD4,IGBP1,NMD3 |
| 1.935e-05 | -10.85 | ZHENG_BOUND_BY_FOXP3 | MSigDB lists | ZHENG_BOUND_BY_FOXP3 | 461 | 103 | 17377 | 2626 |
TCF12,CYTIP,CAST,MRPL39,ACTR3,CDC42SE2,PARK7,CREM,ANKRD28,TET3,RAP1A,MDM2,SP100,THADA,RABGAP1L,IL6ST,RCSD1,CDKN1B,TRA2B,NUP153,FAM76B,AQR,MGAT5,PTPRK,SGCE,LARS,PSRC1,CPOX,TLK1,MAP4K4,WIPF1,RRM2,LNX2,UTP3,HERPUD2,STK17B,EPB41,RPL37,RAD51C,JAK1,RBL1,NSMCE2,TPP2,BEND6,LTA4H,GLCCI1,LRCH1,NDUFV2,ZFP91,ANKH,MYNN,SUMF1,TOP2B,ETS1,ASXL2,BZW2,HMG20A,PIP4K2A,RAPGEF6,RGS1,MAN1A1,HERC3,IRF4,RB1,NUS1,ADD3,CWC27,DAD1,SLC35B4,BCL2,MDFIC,CNOT6L,CITED2,VOPP1,CYTH1,AGGF1,ETV3,TNFAIP3,NEK7,MRS2,PSMA1,LLPH,ARID1A,RAB3IP,KDM3A,KLF6,MACF1,SMAP2,ARHGAP15,FAS,ADSS,L3MBTL3,ELMO1,OSBPL8,FAM3C,PIAS2,DTX4,C4orf46,MAP3K5,BTBD10,SNX14,ZC3HAV1,ESYT2 |
| 1.937e-05 | -10.85 | RBM34 (RNA binding motif protein 34) | protein interactions | 23029 | 133 | 41 | 17029 | 2761 |
NIFK,NOP2,RPLP2,ZNF768,URB2,SUZ12,RPL15,CSNK2A1,EBNA1BP2,BRIX1,TTF1,RBM4,APP,KRR1,PTPN2,DDX56,NVL,NOC2L,RPF2,DDX31,ZC3H3,FTSJ3,NOL12,STAU1,ZNF512,GTPBP4,RPL8,RPL6,PRKRA,MAK16,CENPU,NSA2,ZNF777,RPL32,RRS1,CCDC59,ZC3HAV1,IFI16,GPATCH4,PRPF4B,CCDC137 |
| 1.940e-05 | -10.85 | Vpr-mediated nuclear import of PICs | REACTOME pathways | R-HSA-180910 | 33 | 16 | 10287 | 1696 |
NDC1,NUP188,RAE1,NUP54,NUP155,NUP205,KPNA1,NUP210,BANF1,NUP107,NUP153,NUP62,NUP58,NUP85,AAAS,SEH1L |
| 1.953e-05 | -10.84 | GSE7852_LN_VS_FAT_TREG_UP | MSigDB lists | GSE7852_LN_VS_FAT_TREG_UP | 190 | 51 | 17377 | 2626 |
PIGN,PPCS,SHPRH,TRMT6,MOGS,CDCA8,STARD7,TOP2B,GMCL1,NHLRC3,ZNF518A,SDHA,BZW2,PIP4K2A,NUP205,CNOT3,FBXO22,UBLCP1,C2orf68,LIN9,C1GALT1,MLX,MTMR4,HDAC7,RABGAP1L,TBC1D14,DCP1A,BCAP29,CNN2,RNF135,MCMBP,SEH1L,SMC4,CSTF1,PPIF,EIF3L,KAT2A,NSUN2,STX16,DHX57,SUGP1,KPNA4,CDCA4,TTC13,LUC7L3,STK38,PRPS2,BBX,RNF38,CRCP,RUVBL2 |
| 1.953e-05 | -10.84 | GSE17721_LPS_VS_POLYIC_4H_BMDC_DN | MSigDB lists | GSE17721_LPS_VS_POLYIC_4H_BMDC_DN | 190 | 51 | 17377 | 2626 |
TCF12,NDUFV2,FEZ2,C19orf53,TMEM203,TSC22D3,UCK2,RACGAP1,PXMP2,XPO7,HCFC1R1,APP,C14orf119,FANCL,LPIN2,ADCY9,MEA1,ORAI1,PDCD2,NDUFS8,MRPL40,GLE1,TMEM14C,FGFR1OP2,KCNAB2,KDELR1,CSNK1G2,AATF,POLK,FOPNL,PRKDC,METTL5,MRPL12,LDHA,GMFB,EMP3,DNAJC9,ANAPC2,MEF2D,MBD3,EIF3H,MTMR3,KIF2A,MRPL2,CEP55,H2AFX,IARS2,RNF38,KPNA2,SMAD4,SNAPIN |
| 1.954e-05 | -10.84 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest | biological process | GO:0006977 | 62 | 23 | 17256 | 2622 |
PLK3,BTG2,CCNB1,SOX4,CNOT11,CNOT3,CNOT9,PCNA,MDM2,RPS27A,CENPJ,E2F4,TFDP1,E2F1,PML,GTSE1,CDKN1B,CNOT6,CHEK2,TFDP2,CNOT6L,CDK2,CARM1 |
| 1.980e-05 | -10.83 | programmed cell death | biological process | GO:0012501 | 1039 | 206 | 17256 | 2622 |
MAX,DDX47,PDCD6IP,TSC2,THOC1,NF1,TMEM109,XIAP,CSNK2A1,CUL1,UBE2Z,MIEN1,MAPK14,BECN1,BIRC2,CDK5,NEK6,GSDMB,SIVA1,ATG3,ETV6,NOC2L,FNIP2,SENP1,DRAM2,CCAR1,TIMM50,RYBP,BAK1,PLK3,PGAP2,AKT2,MCL1,TOPORS,LRP5,EAF2,BRCA1,DIDO1,MCM2,STK17B,BRMS1,AXIN1,PRDX5,BCL7C,OGT,STK11,CHEK2,CLU,ROCK1,E2F2,TRAF5,RTN3,ZMAT3,CAPN1,SMNDC1,PDCD4,UBE2D3,CLSPN,GADD45G,DHX9,CDIP1,CIB1,TIA1,MEF2A,CYCS,NOTCH2,NCKAP1,PDCD7,PSEN1,RHBDD1,APOPT1,JMY,CFLAR,RTKN,RB1,TIGAR,DAD1,XPA,EI24,MSH2,DAPK1,ARL6IP1,BCL2,MYDGF,KDELR1,EIF5A,PIGT,NOA1,OXR1,ERO1A,BCLAF1,UBE4B,PKM,CYFIP2,FXR1,APPL1,SLTM,RHOB,DAPK3,FAS,FNTA,KPNA1,SIAH2,MAP3K5,TMEM14A,CYLD,DNMT3A,TRAF7,IFI27L1,RPS6KA1,RAF1,DYNLL1,TPX2,RRAGC,PLAGL2,BCL2L1,IRF3,DUSP22,APP,BCAP31,MOAP1,PDK2,BABAM2,TNFAIP8,SIAH1,RALB,PDCD2,CDKN1B,BCAP29,TP53BP2,ATF2,HTRA2,PDCL3,EBAG9,PPIF,BIRC3,POLR2G,TAOK1,CUL3,HTATIP2,MEF2D,CADM1,VDAC1,PPP2CA,DNAJC10,DAP3,HINT1,FASTK,HIPK2,GADD45B,TICAM1,GAS2,MAPK1,EYA2,USP53,BCL2L12,GCLM,PKP4,NDUFS1,MAGEH1,TMBIM4,ANXA6,CASP6,DAP,SRGN,PAWR,CDK11B,FOXO3,MFSD10,FGFR3,PDCD10,CTNNBL1,PTEN,FEM1B,PACS2,MSH6,PDPK1,TGFB1,TNFAIP3,PRKDC,JTB,RFFL,RHOT1,API5,RHOT2,CDK11A,FADD,SH3GLB1,MAPK3,MFN2,CTSL,PDCD6,BIRC5,PRDX3,ELMO1,E2F1,PML,TMEM219,AEN,HMGB2,DDX5,HRAS,ESPL1,HIPK3,FAF1,IFI16 |
| 1.981e-05 | -10.83 | GCNP_SHH_UP_EARLY.V1_UP | MSigDB lists | GCNP_SHH_UP_EARLY.V1_UP | 161 | 45 | 17377 | 2626 |
POLA2,MRPL9,MCM10,RRM1,TIA1,TOP2B,ABCB10,MAPK14,GGPS1,RNF103,MAN1A1,KIFC1,MRPL50,SHC1,INTS7,NVL,MCM5,MTA1,ARHGEF1,NUP107,CLCN6,PDS5B,PRC1,ANKRD13C,ARL5A,FTSJ3,MSH6,LUC7L2,SEH1L,SRSF10,RLIM,FOXK1,VHL,E2F3,AURKB,SMC2,CDC23,ANLN,MATR3,IRF5,SRSF1,NAP1L1,PARG,LUC7L3,KBTBD7 |
| 1.981e-05 | -10.83 | GSE14415_ACT_VS_CTRL_NATURAL_TREG_UP | MSigDB lists | GSE14415_ACT_VS_CTRL_NATURAL_TREG_UP | 161 | 45 | 17377 | 2626 |
NDUFAF2,MDH2,SCYL1,CDCA3,UCK2,UBE2I,GLRX3,PCBP1,POLR3K,RPAIN,FBXO5,TMCC3,LYAR,SIVA1,TTC9C,ZFYVE27,GEMIN6,TAGLN2,TMEM136,CLTB,EEF1D,CARS2,GINS1,POLR2L,PBK,LDHA,RNPS1,CYP20A1,RRM2,ADSL,GLO1,FADD,ASF1B,BIRC5,NIP7,DCK,TIMM17A,TFDP1,KPNA2,SCARB1,TAF12,PGAM1,CHID1,ATP6V0E1,FAM72A |
| 1.983e-05 | -10.83 | GO_NUCLEAR_PORE | MSigDB lists | GO_NUCLEAR_PORE | 79 | 27 | 17377 | 2626 |
EIF5A,NXT1,NUP188,RAE1,NUP54,RANGAP1,NUP155,AGFG1,NUTF2,XPO7,NUP205,KPNA4,KPNA1,AHCTF1,NUP210,SNUPN,NUP107,NUP62,KPNA2,NUP153,GLE1,MVP,NUP85,AAAS,IPO4,SEH1L,TMEM33 |
| 1.991e-05 | -10.82 | DEAD/DEAH_box_helicase_dom | interpro domains | IPR011545 | 67 | 24 | 18492 | 2768 |
DDX58,DDX28,RECQL,SNRNP200,DDX47,DDX24,DHX29,YTHDC2,DHX9,DDX20,BLM,DDX39A,DHX15,DHX57,DDX23,DDX17,DDX56,DHX16,EIF4A3,DDX31,DDX5,DDX42,POLQ,DDX52 |
| 1.993e-05 | -10.82 | G-protein_beta_WD-40_rep | interpro domains | IPR020472 | 84 | 28 | 18492 | 2768 |
WSB2,CORO7,COPA,TRAF7,RAE1,WDR1,POC1A,WDR18,SMU1,STRN4,WDR82,WDR5,GNB2,WDR48,COPB2,GEMIN5,WDR44,TBL3,DCAF11,FBXW2,PRPF4,TAF5L,RBBP4,STRAP,SEH1L,WDR41,MLST8,PRPF19 |
| 2.003e-05 | -10.82 | TSNAX (translin associated factor X) | protein interactions | 7257 | 103 | 34 | 17029 | 2761 |
TCF12,DYNLL1,GADD45G,HEXB,NUF2,PMF1,UBE2I,LYN,CREM,EXOSC7,KIF14,EFTUD2,MRPS27,STRAP,METTL1,MLEC,PBXIP1,SMU1,FAM133B,FXR1,GAR1,TXNL4A,MAK16,PRDX1,KIF2A,PDCD6,SYNCRIP,NSMCE2,STAT1,MRFAP1L1,TAF12,DMWD,ECPAS,PDF |
| 2.004e-05 | -10.82 | GO_OXIDOREDUCTASE_COMPLEX | MSigDB lists | GO_OXIDOREDUCTASE_COMPLEX | 92 | 30 | 17377 | 2626 |
NDUFA5,NDUFV2,NDUFS1,NDUFB6,UQCR10,RRM1,RRM2,NDUFA4,NDUFA7,OGDH,NDUFB1,FOXRED1,SDHA,PARK7,PDHX,NDUFS7,NDUFS4,SDHB,PDK2,NDUFV1,NDUFA2,NDUFB4,NDUFA11,DHTKD1,NDUFB9,NDUFS8,NDUFS5,NDUFA3,GPD1L,GCSH |
| 2.010e-05 | -10.81 | RICKMAN_METASTASIS_UP | MSigDB lists | RICKMAN_METASTASIS_UP | 312 | 75 | 17377 | 2626 |
NAT9,ATXN3,ST13,TMX4,TMEM97,DHX8,AGFG1,LCLAT1,PAPOLA,PSMD1,NUP107,EFCAB11,PARL,APOOL,METTL9,RBM15,ILKAP,RLIM,COPS8,VHL,RNF25,BOLA1,CADM1,TMEM201,ZMYM3,AMZ2,PDRG1,CENPBD1,TFDP2,ZNF75A,SLC25A33,SVIP,USP13,SEPHS2,NDUFS1,PKP4,MAGEH1,HJURP,TRIP12,SRSF6,MECP2,B4GALT5,NUP54,CDCA3,VPS45,CTCF,SUPT7L,ITGB5,PDXDC1,ZNF92,YY1AP1,GATC,ZNF449,CCP110,PPIG,TPST1,TTC17,CREB1,YTHDC1,ADAM17,ZMYND11,NUDT4,SCFD2,FAM133B,C14orf132,PPWD1,ARL17A,CAND1,AKAP1,GNAS,RBM25,PGRMC1,DTX4,ZFP90,ALS2 |
| 2.022e-05 | -10.81 | GO_GLYCOSYL_COMPOUND_METABOLIC_PROCESS | MSigDB lists | GO_GLYCOSYL_COMPOUND_METABOLIC_PROCESS | 333 | 79 | 17377 | 2626 |
NDUFA5,COX15,DNMT3A,PPCS,NDUFB6,UQCR10,UCK2,OLA1,UCK1,ADPGK,SLC35B2,ATP6V1B2,DUT,PPCDC,AKR1B1,UPRT,NDUFB9,SLC26A2,AHCYL1,DNMT1,PDCL3,ENPP4,ATP6V0A1,PFKFB3,NDUFA7,OGDH,ICMT,NDUFB1,TAZ,MAT2A,STOML2,NDUFA11,MLYCD,COX5A,DHTKD1,UQCRH,PFKP,NDUFV2,COX5B,GALK1,NDUFS1,MECP2,MRI1,NDUFA4,ABHD14B,CYCS,COX4I1,NDUFS7,NDUFS4,MAT2B,ERH,NDUFV1,NDUFA2,NDUFB4,ATIC,MSH2,ATP6V0A2,AHCY,NDUFS8,CYC1,NDUFA3,AMPD2,TGFB1,TK1,GUK1,AMD1,LDHA,ADSL,DCTD,HSPA1B,ADSS,DCK,TYW5,COX7A2L,COX8A,IMPDH1,GPI,NDUFS5,PGAM1 |
| 2.025e-05 | -10.81 | GO_COPI_COATED_VESICLE | MSigDB lists | GO_COPI_COATED_VESICLE | 22 | 12 | 17377 | 2626 |
TMED7,COPA,TMED10,COPE,SCYL1,PACS1,ARF1,TMED3,COPG2,TMED2,COPB2,KDELR1 |
| 2.026e-05 | -10.81 | GO_VACUOLAR_TRANSPORT | MSigDB lists | GO_VACUOLAR_TRANSPORT | 230 | 59 | 17377 | 2626 |
RAB14,SNX27,CHMP2A,ANKRD27,CORO7,SYS1,RAB11B,TRAK1,VTI1A,TGOLN2,RAB6A,BECN1,RAB11A,STAM,VPS25,SCYL2,KLHL20,SNX18,RAB35,TBC1D14,AP1M1,CORO1A,LMAN1,PIKFYVE,DCTN1,NAGPA,SNX8,GCC2,RHOBTB3,SNX2,RAB7A,DENND1B,ADRB2,CHMP2B,STX16,GOSR1,RAB5B,ERC1,PICALM,RHOB,SCARB2,HGS,CHMP4A,WAS,TBC1D17,SURF4,VPS26B,RPS27A,AP1S1,CHMP4B,VPS4A,EHD4,CLN3,CHMP7,SMURF1,ABCA1,VPS29,ALS2,SNAPIN |
| 2.030e-05 | -10.81 | SH3KBP1 (SH3 domain containing kinase binding protein 1) | protein interactions | 30011 | 220 | 60 | 17029 | 2761 |
PDCD6IP,RAF1,KLF13,KIF23,RACGAP1,UBE2I,CSNK1A1,LYN,RAB11A,BIRC2,TUBGCP2,PABPC4,NPLOC4,ASAP2,SH3BP1,MCM5,SEC24C,ARHGEF1,CAPZA1,PRC1,DNM2,GTSE1,SEPT11,ANAPC7,DNMT1,CARMIL1,PABPC1,ARHGAP17,DDX28,PSRC1,SEPT9,PRRC2A,MRPL12,SEPT8,WIPF1,CAPZA2,SEPT7,CDC23,ANLN,SHCBP1,ERC1,SH3GLB1,RPA1,DDX17,MAP3K4,LEMD2,HGS,PDCD6,CDC16,FBXO28,CDC27,MAP4,SH3GLB2,ARAP1,IMPDH1,ATP5F1A,TAF6,HRAS,ANAPC4,FAM83G |
| 2.036e-05 | -10.80 | ECPAS (Ecm29 proteasome adaptor and scaffold) | protein interactions | 23392 | 151 | 45 | 17029 | 2761 |
CEP170B,AGTRAP,FLOT1,UBE2Q1,PTP4A3,MAN2B1,DNAJB1,DNAJB9,SF3B2,DST,KIF5B,FARSA,PSMD1,PSMA6,KDM2A,UCHL5,RAD23B,RTCB,RP2,GNAI2,HNRNPM,DCTN1,LDHB,SPTAN1,MOB4,TXNL1,SLC39A9,CDKN2AIP,CCDC57,TIMM8B,MKI67,RABIF,BRCA1,ADRB2,EIF4H,KDM3A,PSMC4,PCM1,ATP1A1,PSMD8,PSMD3,TATDN1,CLN3,RPS26,TUBB |
| 2.039e-05 | -10.80 | AURKB (aurora kinase B) | protein interactions | 9212 | 160 | 47 | 17029 | 2761 |
SKA3,MAPRE1,CYLD,KLHL21,TPX2,CIB1,MOGS,CDCA8,FLOT1,RACGAP1,NUF2,UBE2I,APP,CDC73,DTL,KIF5B,RB1,PPP6C,MRPS27,NOC2L,TFG,RBM12B,DCTN1,CDC37,CDC5L,MAPRE2,TACC1,NSUN2,CUL3,AURKB,PRPF3,PKM,MARK2,CBX3,ANKZF1,PPP2CA,SEPT1,EIF4ENIF1,CDC27,BIRC5,TBL3,LRPPRC,FKBP5,DDX5,ZC3HAV1,DDB1,TUBB |
| 2.041e-05 | -10.80 | translational termination | biological process | GO:0006415 | 96 | 31 | 17256 | 2622 |
MRPL9,MRPL42,MRPS2,MRPS15,MRPL39,GSPT2,MRPL43,MRPL12,MRPS26,MRPS10,MRPL16,MRPS14,GFM2,MRPL19,MRPL50,MRPL2,DAP3,MRPL55,CHCHD1,MRPL27,MRPL34,MRPS27,MRPL54,MRPL48,MRPL40,MRPL21,MRPL11,MRPL13,MRPL3,MRPL32,MRPL57 |
| 2.041e-05 | -10.80 | cotranslational protein targeting to membrane | biological process | GO:0006613 | 96 | 31 | 17256 | 2622 |
SRP72,RPL29,RPS15,SEC61B,RPL35,RPS2,RPLP2,RPL6,RPS10,RPL38,RPL8,RPL15,SSR2,RPS24,RPL27A,RPS9,RPSA,SSR1,RPL23A,RPL36,RPL11,RPL37,RPL32,SEC61A1,RPL17,RPS27A,RPS14,ARL6IP1,RPLP1,RPL19,RPS26 |
| 2.050e-05 | -10.79 | YWHAB (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta) | protein interactions | 7529 | 381 | 93 | 17029 | 2761 |
BCCIP,CYLD,LUZP1,TSC2,NF1,RPS6KA1,RAF1,CSNK2A1,SDHA,STAM,APP,PARK7,EDC3,TBC1D22A,MTMR4,PIK3R2,CDKN1B,MAST2,CDC25B,TP53BP2,ATF2,SRSF10,SRPK2,SNRNP200,CUL3,RNPS1,NFATC2,MCM2,DHX15,GIGYF1,CHAF1A,EPB41,OPTN,AFDN,STK38,ITGB1,H2AFX,VIPAS39,TRIM32,PTPDC1,REEP4,ARRB2,CBX4,PARD3,TUBB,CEP170B,UNK,ZCCHC8,NKD2,KIF23,KLC1,RACGAP1,AKT1S1,NCKAP1,CDK11B,DOCK11,PITHD1,FOXO3,RAPGEF6,CDC73,RTKN,DTL,KIF5B,CENPJ,HDAC7,KIF13B,CAPZA1,DAPK1,ARHGEF2,LDHB,AMPD2,SAMD4B,TNFAIP3,FOXK1,DENND4C,KIAA0930,MTMR12,CYFIP2,PDE3B,MARK2,MAP2K2,HSPA1B,TFEB,TSC1,HGS,CCDC6,USP32,YWHAZ,ATP5F1A,SRSF3,WDR62,YWHAH,ALS2 |
| 2.051e-05 | -10.79 | REACTOME_INTERACTIONS_OF_VPR_WITH_HOST_CELLULAR_PROTEINS | MSigDB lists | REACTOME_INTERACTIONS_OF_VPR_WITH_HOST_CELLULAR_PROTEINS | 32 | 15 | 17377 | 2626 |
NUP188,NUP210,KPNA1,RAE1,BANF1,NUP107,NUP54,NUP62,NUP153,NUP155,SLC25A5,NUP85,AAAS,NUP205,SEH1L |
| 2.064e-05 | -10.79 | kidney | COSMIC cancer mutations | kidney | 15842 | 2411 | 17385 | 2587 |
HECA,ZBTB10,ABCC10,HEXB,CCNL2,FBXO22,EEF2K,THAP4,RAD23B,ATP13A3,DNM2,FTSJ3,USP34,CCDC57,ERCC1,NRAS,EHMT1,KIF15,HNRNPF,WDHD1,MIER2,DIDO1,MCM2,RAB22A,SMAD2,MID1IP1,RPS27A,MYO18A,OGT,MPV17,COX5A,SMAD1,ZNF75A,ANXA11,SLC25A33,ZNF720,SEC61G,GGA1,MUM1,CCZ1,TRIO,CUTA,RAB23,KCTD17,HAUS4,EIF2AK4,APH1B,PARN,CDC73,MYL6B,ATG4A,TMEM179B,PDXP,SMC3,GEMIN4,MVP,NUP85,PPP6R1,PABPC1,NSUN4,PPA1,IFRD1,AGGF1,FOXK1,RBM42,GTPBP4,MAP7D1,MRPL16,ELK1,EIF4H,RDH11,MAGED2,KPNA1,ETS2,TYW5,WIPI2,RUFY3,PDLIM5,ACSF2,EXOC3,RHOG,STARD7,C5orf30,VTI1A,SLC35B2,INO80E,RCOR3,LCLAT1,CPNE3,KIAA1147,RBM23,ZNF420,AHCTF1,TBC1D22A,TBC1D14,GMEB1,NSFL1C,SEPT11,GPD1L,ZC3H3,ARL5A,PDCL3,SNX8,ERMP1,IDH3A,HTATIP2,MEF2D,GSTCD,TANC1,MAT2A,VPS26B,CORO1C,NSMCE2,CAMKMT,PPP5C,PITRM1,TUBB,COMMD10,ZNF445,SRSF6,HABP4,CCM2,FLOT1,BTN3A1,ATG2B,PPP1R3B,GOLM1,ZBTB45,HUWE1,ZNF260,NAA50,ANXA5,LTN1,KANSL2,UBE3B,NAP1L4,ZNF710,ST8SIA2,RPL22L1,MED22,SPTAN1,STAU1,DDX24,TCTEX1D2,TACC1,MRS2,LDHA,HEBP2,LLPH,RAB3IP,TTC33,PICALM,SH3BP5,SLC19A1,ACOX1,FAM3C,AEN,PARP10,YWHAH,THAP5,GPATCH4,FAM129A,TRIM11,YTHDC2,SNX15,RBM8A,NENF,SND1,RUFY1,TRIM65,ZER1,PRNP,KRR1,RAB8A,NUP210,NT5DC1,NOC2L,EIF5,TACC3,VPS13B,RYBP,PTPN18,MIOS,MBLAC2,SNRPB,CDC6,UTP3,PBRM1,ODC1,USP21,TRAM2,FBXO28,BCL7C,ARRDC1,ADAM9,DVL1,NUMB,ZNF564,FUBP1,PARP12,ZCCHC9,CENPF,LAMTOR3,NCKAP1,LYRM2,RSAD1,TNS3,SUB1,RINL,SSBP3,KIF13B,MBD2,XPA,AHCY,RBM3,GLE1,MRPL48,LRSAM1,HDHD2,NTPCR,NSDHL,AMD1,CAMSAP1,ZNF761,METTL22,ICAM2,STYXL1,APPL1,BBS12,ANKRD46,RXRB,SDHB,PCM1,GALNT2,TMEM168,NLRC5,RUVBL2,BTBD10,MYO9A,CCNB2,USP7,GLT8D1,SUCLG1,ARID2,TMX4,SLC2A1,ATP6V1B2,PCBP1,LYN,BCAP31,VAV1,TMEM69,MRPL50,PSMA6,ZNF473,ZNF302,BRPF3,TARDBP,BCAP29,CTDSP2,PRPF19,PPIF,KDM3B,MND1,CLCN3,BIRC3,RAB7A,ANKRD33B,PPIE,CHMP2B,VDAC1,EIF3H,TMEM201,GLOD4,IDE,DHX16,UHRF2,XRCC3,CHMP4B,PARD3,BCL2L12,C19orf53,MCM10,KLHL21,PDAP1,TMX3,CDCA8,GTF3A,ARF1,SLC12A9,TUBGCP2,DNAJB9,HOMER1,WBP1L,POLR1B,RNF5,RBM15B,PPAN,RHOA,RPRD1A,BTAF1,TOP3A,ARHGEF12,PCGF1,DDX23,RAB18,CACNB1,TRIM26,PDCD6,ATP6V1D,L3MBTL3,NEIL3,CTBS,BBX,IMPDH1,TAF12,NR2F2,PGAM1,HIPK3,IFI16,TXN,NUP188,H2AFZ,PNISR,TMEM203,PRKCSH,USP39,UBE2I,PARK7,SLC25A37,ZNF428,RAB4A,TRA2B,SUCLG2,TAF5L,CISD2,SMARCE1,ZNF800,CDC5L,SGCE,OSBP2,NSUN2,USP22,EIF3A,ZMYM3,DOT1L,IWS1,ANKRD10,WAS,KIF18B,TPP2,C1orf109,ZMAT3,B4GALT2,PRPF38B,RECQL,C9orf78,EWSR1,GADD45G,RRM1,ACAP1,B4GALT1,CYCS,FAM136A,SUPT7L,TMEM165,NPLOC4,CNOT3,WDR48,SPAG5,RTKN,CEP104,EXOSC7,KLHL5,LRRC8D,PPP4R1,MSH2,PIGG,FBXL7,OSTF1,MRPL40,SYTL3,FAM171A1,APOL1,EIF5A,GCC2,PRIM2,ELL2,RDH10,MFNG,RPS24,GORASP2,CAPZA2,ADRB2,CCT8,MTR,PHF6,PFDN5,SLCO4A1,TTC13,GOLGA2,RBMX,MED15,PIAS2,APPL2,SAMD8,NUDT3,CDKN2A,ZNF511,ATXN3,RAF1,KIAA0232,C2orf49,EPM2A,CCNA2,MTMR4,BRI3,TP53BP2,AQR,RBM12B,ILKAP,CDK12,SAP30,BRD4,DRAP1,NARF,LRRC8A,ELP4,ABHD11,PKMYT1,ASB13,TRIM28,SUPT16H,EIF3K,CHMP4A,CBWD1,ATF6,XRCC4,PRPF4B,ADAM23,NDUFS1,DEPDC1,MECP2,SECISBP2,HMG20A,WWP2,JAKMIP1,SLC25A36,CCNK,DNAJC8,ELP5,AXIN2,CITED2,JMJD4,KAT2A,TMEM126B,RABIF,ADSL,PACS1,BMS1,KCNQ1,OTUD3,ARSK,MACF1,KIF11,KLF6,COMMD4,SMAP2,FADD,SH3GLB1,MYO1F,CBX3,TMEM127,PPP1R11,DUSP11,DDX5,WDR62,TAF6,ESPL1,PURA,DDB1,DEF6,IPO4,FAM83G,UBL3,NAT9,PIGM,LYRM4,GPR132,UBE2Q1,PTP4A3,BRIX1,MRPL19,SF3B2,PCYOX1L,CDC42,SYNM,GOT2,JAZF1,HADHB,RPF2,CNNM3,CARM1,SRPK2,WDR41,LARS,ZCCHC10,CCDC138,LRBA,TMEM216,SUMF2,KMT2C,OGFR,PRPSAP1,ASF1B,RPL37,MAN2A2,EIF4ENIF1,U2SURP,MIA2,ZNF268,VPS4A,ATP6V0E1,PPP1R2,PM20D2,XPNPEP3,RGS2,LYAR,POLR2I,TRAFD1,SUGP2,GBA,EIF2A,SYVN1,DAPK3,ARHGAP15,MASTL,UAP1,NFIL3,FN3KRP,YWHAZ,CTSA,TMEM14A,TOB1,TSEN15,ADNP2,TCF12,PRKAB1,MDH2,SMARCA4,ORC1,RRN3,UBXN2A,IARS,CD3EAP,KIF14,EXOSC1,CS,CLTB,DNAL4,CSTF1,POU2AF1,UBQLN4,PGGT1B,SELPLG,SMU1,ATXN1,GLO1,OGDH,BICD2,CADM1,EDEM2,HERPUD2,TOLLIP,FANCE,MBD3,PDHX,RPS9,ALKBH6,SURF4,DUS3L,ARNTL,ANP32E,FKBP5,TMEM101,CCDC125,ABCA1,PDCD2L,GCLM,RAE1,DCTN2,NUP54,CHIC2,PAWR,MXD4,DCUN1D4,PIP4K2A,XPR1,FERMT3,KIF5B,KLHL20,SEC24C,RRBP1,ARHGEF2,ANP32A,LDLRAD3,C12orf75,STAT3,MYO5A,NIPAL3,AMPD2,TXNL1,PHF20L1,DCAF6,FAM49B,TMEM39A,ATP2C1,RFFL,COG1,RCOR1,PRMT2,TFEB,LEMD2,UPF1,ELMO1,ZC3H7B,DTX4,ZMIZ1,TERF1,HRAS,CCDC93,FGFR1OP,TMED7,PIGQ,CNTROB,PPP1R16B,MIS12,GSDMB,TTC9C,PDS5B,NUP153,SENP1,PGAP2,TMEM115,PLEKHM3,DCUN1D5,PWWP2B,TRIM47,WDR11,AXIN1,SMG9,TRIM52,LONP2,NDUFV2,PHF23,CERK,SLC4A2,EZH1,ITGB5,LMNA,MCTS1,DDX56,EIF2S2,SLC38A5,FOXN2,CARS2,PRRC2A,C16orf72,RB1CC1,ZMYND11,PGS1,MYBL2,UHRF1BP1,SRSF5,MPG,MATR3,CYB5A,NCDN,SETD3,TEX30,PTAR1,CNOT6,NDE1,EGLN1,ZNF207,ANKRD27,PPP1R37,ABCA3,SARNP,IVNS1ABP,MON1B,RMI2,TMEM97,NIT2,NUF2,ZNF267,TCF19,TMEM161B,KTN1,APP,PRKD3,CLUAP1,ATP2A2,UTP18,GRSF1,DUT,ZCCHC2,ANAPC7,RNF19A,FAM76B,CLN6,TMEM9,GCC1,RNF169,ADCY7,ATP6V1G1,ENPP4,RNPS1,CDCA2,FKBP3,GPR137,DDX17,CHCHD3,PEX5,CDC16,HIPK2,MBOAT1,TICAM1,PDXK,ZBTB11,ANXA6,TMBIM4,GMCL1,UBE4A,IL21R,ETS1,WRB,ZNF92,PNO1,CAPN2,ADD3,SUV39H2,TTLL12,TPCN1,TMX1,HNRNPM,MFSD12,LDHB,PPP3CA,POLK,JTB,EMP3,MTMR12,ZP3,PDE3B,KIF18A,CCDC6,WNT5B,MAPK6,LY75,SLC25A19,RGL1,PSAP,WDR76,IGBP1,FAF1,SNAPIN,COX15,AGRN,THOC1,GNPDA1,GPBP1L1,PPP1R15B,CSNK2A1,EBNA1BP2,GIT2,BIRC2,ATPAF1,DLG5,ABL2,XRCC2,ZFYVE27,MCMBP,PTPRK,CDC37,METTL1,SP3,HARS,GMFB,ESYT1,ANLN,RAB5B,RHEB,DPYSL3,TBC1D17,TONSL,NRM,NAGLU,ACTB,ZNF45,TMUB1,CTCF,ASAH1,DOCK11,CRLF3,ASXL2,LRRC14,NUS1,SLC27A4,AFF1,MDFIC,MAML1,CYTH1,NQO2,UTP15,EIF2AK1,EIF4G2,ZDHHC3,MOSPD3,ITPRIPL1,CDC27,SNAP23,PRMT7,KCTD7,CYLD,UGP2,COPE,ZADH2,GGPS1,RPAIN,RAD23A,PDK2,ATP6V0B,STRBP,DUS4L,PDCD2,SAP30L,SLC39A9,CLPTM1,RPL29,BTG2,DNAJC9,MTMR6,FRAT2,NFATC2,KDM1B,ARL5B,USP36,CCDC127,MRPL2,ATP1A1,CLK3,PSMD3,MAFK,CEP55,NDUFA11,DNAJC17,ZNF436,NCOA1,SLC25A39,ZC3HC1,ZNF146,ATXN7L2,CDC40,GOLIM4,RRP15,DAP,GNE,SMC6,ARFIP2,NKRF,BZW2,WRNIP1,SS18L1,CENPM,PTGES3,CAMK2G,MLEC,ZNF202,PPWD1,FAM50B,RHOT2,NEU1,TPD52L2,GOLGA7,TWSG1,PGRMC1,GLG1,FAM126A,RPS6KC1,UBE2C,PPCS,NDUFB6,TMEM41B,ZDHHC8,PLXNA1,CCNB1,SLC20A1,COMMD6,ABHD14A,POLR3K,ASAP2,SNUPN,CNPY4,PLCL2,TFG,SEH1L,ATG9A,PBK,MKI67,DDX20,AMDHD2,SLC17A5,GALNT7,CCNF,FOXRED1,RBM47,PTER,WDR4,DHTKD1,TRAF5,HDAC2,PWWP2A,HSPH1,LIME1,MAPRE1,CHTF18,KIF23,SLC35B1,NOTCH2,PMF1,JMY,FKBP1A,SLC31A1,SNX18,ATIC,CTPS1,ATP6V0A2,PIKFYVE,RNF135,LPCAT1,EEF1D,TMED2,FTL,PHF10,DDX28,SIGMAR1,PIP4K2C,FAM133B,RIT1,PLEC,KDM3A,SF3A2,FAS,EPRS,ZNF777,TMEM54,QARS,PPP3R1,TCOF1,CABLES1,NRBP1,DNMT3A,RWDD1,CKLF,TRIP10,SF3B1,CAST,SUZ12,RPS6KA1,RAC1,GPR89A,OLA1,SNN,GNB2,FLAD1,APLP2,KDM2A,CDKN1B,TNPO2,TALDO1,GPX4,ATP13A1,MAPRE2,RFC3,ERF,CUL3,SLBP,KIAA1586,H2AFV,GAR1,PSMB9,POLG2,DHX57,NSA2,HSPA4,JAK1,TBL3,SEL1L,H2AFX,KLHDC4,B4GALT3,PDCD11,ATMIN,POLQ,OTUD5,NCOR2,ANKRD13D,PKP4,BABAM1,CDCA3,SLC25A12,BLM,TMCC3,GTF2F1,CRAT,AHSA1,PRC1,UPF2,COPS7B,SLC38A10,CNOT6L,CNPY3,UBE2M,IFT46,TMEM160,TSHZ1,ZFP64,DENND4C,DENND1B,WDR18,RPL8,ILF3,LRRC1,RHOT1,TSR2,MARK2,ECH1,PRDX1,PLD3,NUCB1,GNA12,FBXO21,C1orf131,PRDX3,PFDN4,TFDP1,STX18,KHSRP,CPEB2,SSSCA1,VPS29,BYSL,S100PBP,MIB2,IER2,PTMS,NOP2,UBN1,DCAF15,NF1,ALKBH5,MOGS,UBE2Z,TAF6L,BECN1,MAPK14,SNAPC4,RNF103,BCAT2,MBD4,METTL14,ZNHIT6,IMPAD1,RCSD1,PHTF1,KIF22,ZBTB22,NFU1,OGG1,TRIM14,COPS8,FYTTD1,TRIM8,RRM2,SOX4,ABHD5,UBTF,CXXC4,PAF1,UEVLD,SPATA2,PQBP1,IARS2,ATXN2L,GALNT10,STARD3NL,PIGN,AGTRAP,CIB1,XPO7,SRRT,ZNF449,CAPZA1,GLTP,BCL2,KIFAP3,N4BP2,HP1BP3,VOPP1,THNSL1,ISG15,CAND1,GNAS,TSC1,RBM25,CDCA5,ZFP90,RBBP4,ZBTB24,SMARCD1,MBD1,WASF2,MMACHC,TOMM20,IFI27L1,GNPNAT1,MPHOSPH8,HNRNPUL2,CHD1,MEAF6,C2orf68,CCDC50,AKAP8,PARL,RPN2,CHTOP,FAM3A,F2R,TMEM14C,SCYL3,ABI1,MOSPD1,RLIM,FAM172A,ZNF500,PSMB7,NLN,WIPF1,BOLA1,BUD13,PEF1,EIF3G,BTBD1,TAB2,TULP3,WDR59,CANT1,SCARB1,GAS2,USP11,SMURF1,PPP2R2D,TSPAN5,CDS2,MAGEH1,MRPL42,EYA1,CDK2AP2,MRPS26,LETMD1,KLF13,HDDC2,RGS1,MAN1A1,FBXO5,GART,PELO,TANK,BRD7,MRPL11,SAMD4B,ZDHHC18,GTF3C6,POLR3GL,WDR81,MEN1,ZNF407,MFN2,COX8A,MBD6,SRSF3,ATP6V1C1,IDH3B,TATDN1,TSC2,LACTB2,RBM4,ZNF275,ANKRD39,RPL23A,CDKN2C,NAPG,USF1,DNAAF2,MECR,AP1M1,UPRT,CRY2,ECD,RNF26,TIPARP,LRRC59,ANKRD9,RHBDD2,MGAT5,BAK1,ZNF559,RHOBTB3,GABPA,WBP1,NUTF2,ARF4,KRIT1,AHNAK,RAD18,PDRG1,RNASEL,CHPF2,PDCD4,SMNDC1,NXT2,HIVEP3,KIAA0100,CLSPN,RHOC,DHX9,PDCD7,PSMD9,HAUS2,COPB2,CD59,TFAP4,RNFT1,MEGF8,RIMS3,FBXO7,EFTUD2,CPSF4,MRPL21,PHKG2,LUC7L2,SRSF11,EIF3L,MTA2,TYW1,USP10,ITM2A,SSR2,BCLAF1,SFXN5,FNTA,PDLIM1,TXNDC16,ZNF830,TMEM159,MRPL3,ALS2,FAM72A,TRIM41,KARS,NQO1,POC1A,ANK3,PTTG1,TPX2,TBC1D13,GLRX3,REPS1,ABHD16A,FBXL6,SH3BP1,MTA1,UBA5,CLCN6,INTS12,RPRD1B,CGGBP1,CPNE1,SEC61B,POLR2L,FAM118B,GOPC,E2F3,CIRBP,RPL38,CRNKL1,PFKFB3,GORAB,RAB1A,GIGYF1,TMEM184C,PPP2CA,KIF2A,CCDC14,LSM6,RNF38,SNRPG,DMWD,USP13,MZT1,ZFP91,TRMT6,IP6K2,WDR5,SLC25A43,PMVK,IFT27,NEIL2,RRP36,SRXN1,RPA2,PSMD2,CLIC4,PDCD10,CBWD2,COQ4,ITGB8,ARF5,ARHGEF1,FBXL19,GTF2H2,TTPAL,UTP20,MAGT1,GPS2,DBI,SSNA1,CD81,TMEM131,WDR13,FANCI,PAPOLA,CREM,FANCL,TET3,GLIS2,IL6ST,INTS1,POP7,SLC44A1,MTPN,ASB6,PLK1,CELSR2,SEPT9,RBX1,RAD51AP1,ZBED5,CKAP2L,PSMG1,UBE2V1,EAF2,IL12RB1,LUC7L,LSG1,NECAP2,C1orf122,ALG3,TRIM4,AGPAT2,CHD3,ZNF367,E2F4,PRPF4,KPNA2,BEND6,CLN3,DNAJC30,FAM208A,NGLY1,POT1,MYL12B,RMND5A,HJURP,PHB2,DNAJB2,FAM53C,NKD2,SDC2,KLC1,CDK13,ADCK5,COX4I1,DNAJB1,RAB6A,ARID1B,C1GALT1,MLX,UBE2Q2,CCP110,ZNF746,ARL6IP1,CTR9,NIPSNAP1,ABHD2,DCAF8,ACSL3,LDB1,MAP4K3,ARMC8,RBM38,NMT2,IRF5,HAUS8,MBIP,ORMDL2,COX7A2L,ZDHHC7,SIL1,DTD1,UNC13C,BCCIP,SART1,TRAF7,NDUFAF2,TOR1AIP1,ZNF416,LAGE3,ZFYVE21,TM9SF3,RRAGC,ZNF121,OIP5,NRF1,WDR44,PPME1,PIN1,EFCAB11,RPAP1,CABLES2,LMAN1,AHCYL1,TOP1MT,STRAP,SPSB3,ZNF583,SNX25,ARHGAP17,POLR2G,KIAA0040,ZNF780B,NUP155,DCLRE1C,MRPS14,RHBDF2,SUGP1,RBL1,FASTK,UBXN2B,STK38,AP1S1,SPRYD4,SLC22A23,CHID1,SMAD4,RAD51D,SLC30A9,CMAS,UNK,NADSYN1,HMGN3,NCAPG,SCYL2,FZD6,HERC3,GTPBP3,CTSS,ORC3,RNLS,YTHDC1,ACP2,HMGN5,CSRP1,METTL5,TUFM,RANGAP1,PNPLA8,HAGH,API5,ZFR,SEC23IP,E2F1,TMEM219,USP20,RBPJ,PDCD6IP,MAX,GXYLT1,LUZP1,ADAM10,CXXC1,TSC22D3,AP3M2,CUL1,GYG1,NANS,OAT,MYEF2,ANKRD26,PA2G4,NOL11,FIZ1,ZNF200,MARCH2,SLC26A2,SRP72,KLF10,LACTB,RFC2,CBFB,RAB2B,PRIM1,MAP3K4,HHEX,LUC7L3,RPS14,MAP4,MRPL27,BTF3,PTPDC1,NMD3,PTOV1,COX5B,DNAJC5,SCOC,DHPS,POLR2K,ANKH,VAV2,PRKAA1,C16orf87,GSPT2,TATDN3,DLGAP4,PXMP2,PRPF39,PSEN1,ZNF79,PDXDC1,VPS25,NDUFS7,YY1AP1,C12orf10,FAM192A,RPN1,LHX8,ARPC5,ZNRF2,TPST1,DAPK1,CYC1,SOCS5,FDFT1,PIGT,EMB,WDR1,ZNF574,C1orf35,EXOSC9,ARID1A,PTTG1IP,FXR1,GOSR1,MAP2K2,TWISTNB,AKAP1,XRCC5,HMGN2,PI4K2A,CAT,DERL1,MTHFD2,HSPBP1,CEBPG,ARAP1,USP32,FAM83D,CABIN1,SMPD4,GPI,CYTIP,TP53RK,REPS2,RAB11B,UROD,SLC39A13,POMP,BCL2L1,DECR1,RALB,SIAH1,ADCY9,LPIN2,MRPS27,SOCS6,TTC3,RNASEH2A,ANKLE2,CDC123,OAF,VDAC2,EDF1,EML4,ERC1,AMZ2,ANKZF1,RAD51C,ZNF282,DSN1,DDOST,HINT1,DGCR8,SAFB,HAGHL,RWDD4,FTSJ1,LMBR1,NCLN,BEND3,EYA2,DYNC1LI2,MANBA,B4GALT5,SLC41A1,FAM76A,TKT,CBLL1,ARGLU1,LANCL1,POFUT1,FAM8A1,HEATR5B,HLA-A,EBP,RFWD3,NDUFA2,FUT8,BTF3L4,PTPN11,MRPL54,FEM1B,RPL19,CNN2,NDUFA3,MTX2,MSH6,PDLIM2,LONRF3,FBXO9,GUF1,RPL32,ZHX1,OAZ2,NDUFS5,WDR91,HIGD2A,GPR89B,RORB,POLA2,ZNF76,COPA,UQCR10,PHRF1,HMGXB3,ABCB10,COMMD5,MAP1LC3B,DST,RAB35,SIVA1,GPATCH1,TCEA1,DRAM2,DEAF1,TRAPPC13,SNRNP200,LAP3,NCK1,VHL,SREK1,ARHGDIB,PITPNB,HSPB11,BRWD1,PPM1G,SH3GLB2,CRCP,BAZ1B,CAB39,ACBD4,STK11,CLU,CHEK2,ZSWIM3,TSTD2,MRPL13,CHPT1,DCAF5,CAPN1,UBE2D3,PPP1R12A,ZCCHC8,NACA,C19orf25,RPL15,PCSK7,EPN1,THRAP3,QSOX2,TTF1,NUP205,PRPF18,CHKA,DTL,MED10,ZRANB1,MCPH1,SLC12A2,ATP6V0D1,CSNK1G3,CREG1,NUDT4,RPL6,VKORC1,SLTM,EVC2,KLHL15,SIAH2,SLC16A1,EHD4,SNRNP70,C11orf1,APOL2,N4BP2L2,SNX27,CHMP2A,CORO7,FEZ2,UCK2,PMS2,UCK1,CLCC1,EXT2,MXD1,USP5,HNRNPA2B1,SAP130,NVL,PPP6C,CYB5R1,ZNF770,EBAG9,RNF25,PCGF6,METTL2A,PON2,HNRNPR,STAT6,HPS5,MAPK1,BRD9,TMEM33,DNAJC2,TRIP12,SHPRH,SCYL1,VPS45,MYO9B,GFM2,SPPL2A,FASTKD3,FGFR3,MZT2A,PPIG,ZDHHC13,TMEM99,H2AFY,NDUFS8,ATG13,ERI3,FBL,FRMD8,SLC35A1,MICAL3,TGFB1,B3GALT6,ELOVL5,HEMK1,TIMMDC1,HELB,PSPC1,MIER1,SCFD2,NDRG3,CDK11A,MTMR3,MEGF9,ACAT1,CENPT,PLOD3,RAB3IL1,ZSWIM6,RAB14,ADD1,KDM4A,MRPS15,XIAP,DHX8,GLUD1,ANKRD23,PABPC4,CDK5,CALM2,PSMD1,NEK6,NSRP1,RABGAP1L,SRSF4,FNIP2,KCNAB2,PCBP2,MLST8,PLK3,ZNF672,HSDL1,TOPORS,MCL1,PPFIA3,SMC2,ICMT,SLC50A1,STOML2,LIMK1,ZNF689,PRDX5,ATE1,MLYCD,ST3GAL2,ATP6V0C,FBXL3,TFDP2,E2F2,PFKP,AAAS,DDX42,SSRP1,MRPL9,MRPS2,STRN4,TOP2B,ZNRF3,TMED3,DDRGK1,RAVER2,GNS,INTS7,INPP5A,MCM5,PHF14,ZNF326,UBE2QL1,NAGPA,ETV3,TSPAN31,DHX29,TEX10,MAN1B1,CBFA2T2,ABCF1,RHOB,LRRC14B,DTWD1,PTPRF,SCARB2,OSBPL11,CCDC86,DUSP3,SLAIN1,MDH1,HEXA,RNF139,SNX14,TRERF1,UBR2,CHD1L,ACTR3,WDTC1,MYH9,CREBL2,NIPA2,PRKACA,SAFB2,ANKIB1,STAM,ARL6IP6,RAB21,SP100,ZKSCAN1,DDA1,NUP107,ANKRD13C,MAVS,CEP63,ATF2,RBM15,DCTN1,SHOC2,PSRC1,MAP4K4,WBP2,ATP6V0A1,NUSAP1,NDUFA7,DNAJA1,TAZ,TAF2,C19orf54,SEC61A1,WDR7,CBLN2,FUS,GEN1,LRP8,COIL,LRCH1,ZNF786,RPS2,SESTD1,TRAK1,JMJD6,SIKE1,AKT1S1,KRI1,FBXO3,ERH,GATC,NDUFB4,PPP1R8,PRDM4,GTSE1,GEMIN6,DCP1A,SGCB,IMPA2,NUDC,PDPK1,TK1,TNFAIP3,GALC,ZNF512,KIAA0930,MRPS10,DDX39A,RPA1,ZNF862,ZNF180,KEAP1,POLE,TATDN2,PITX1,CAPN7,LRPPRC,PML,HMGB2,USF2,ANAPC4,DDX47,MCCC1,CDC42SE2,S1PR2,SEC16A,SSR1,LIN9,PCNA,TRMU,ETV6,PIK3R2,TXLNA,PPCDC,FAM86C1,MYBL1,MRPL32,CCAR1,ABCC5,PBXIP1,BAZ2A,TLK1,MRPL12,EZR,LNX2,LRP5,BRCA1,PRKRA,STX16,EPB41,OPTN,SEPT1,SOCS4,QRSL1,PIEZO1,OSGEPL1,GLCCI1,NUDT11,NAA60,GEMIN7,SEPHS2,LZTR1,RACGAP1,PPP3CB,B4GALT4,RLF,RAPGEF6,SNRNP25,RB1,VASP,VMP1,PPIL2,TIMELESS,AHDC1,ALDH18A1,TMEM8A,ABCC1,PREB,TRAPPC9,AACS,MEMO1,KRAS,RTF1,UBE4B,LY6E,ARPC1A,ZNF174,PSMC4,GOLGA4,PALB2,SYNCRIP,PRPS2,NIPA1,TIGD2,RNF114,FOXM1,MRPL39,XAB2,SUMO2,DUSP22,RPL11,CSDE1,MDM2,CORO1A,MINPP1,METTL9,POC5,DVL2,GM2A,PSMA8,COQ10B,CPOX,SLC26A6,CYP20A1,PRPF3,TXNL4A,SRSF1,DNAJC10,ZNF700,SCAP,PLEKHG4B,TIMM17A,FAU,LTA4H,USP53,INTS2,CTDP1,CDT1,ARID5A,SUMF1,GGA2,AP3S1,CSNK1A1,RMI1,TFRC,PTPN2,IRF4,STARD9,GSTK1,NDUFV1,SLC1A4,CWC27,SLC35B4,DDX31,ABCD1,RPAP3,CNTN5,SNX2,ZMYM5,CHCHD6,BSDC1,KPNA4,CDKN2AIPNL,FBXO41,BIRC5,TFE3,SNAP29,CDCA7L,PKD2,ACADM,CHMP7,SAT2,GCSH,ZNF496,TMEM109,TAP1,YTHDF3,NHLRC3,IKBIP,ELMOD2,KIFC1,DBNDD1,CYB5RL,PARPBP,CDC25B,PRADC1,DNMT1,NOL12,ORAI2,USO1,AKT2,NOL8,GNG7,AURKB,SLC25A5,ZFAND5,MAK16,STT3A,TMED10,PSMD8,EIF2D,ITGB1,PTPN7,UQCRH,RRS1,ARRB2,RTN3,ZNF598,DDX58,WSB2,PPIB,MUT,HLA-E,NDUFA4,MAN2B1,METTL3,CFLAR,NDUFS4,RNF121,MEX3C,KLF16,HDAC7,DAD1,BDH1,PCYT2,GNAI2,ANKHD1,TERF2,MORC3,KCTD20,SEPT8,DCTD,PKM,TOMM40,PATL1,ADSS,SERTAD2,ZFP92,NSF,DCK,ERGIC3,ACLY,LPCAT4,VCPIP1,YY1,PPP6R3,PPP6R2,MAP3K5,RNF14,CDK2,ZC3HAV1,ZBTB37,URB2,EIF3D,MAGED1,KLHL18,ADPGK,SLC25A44,AP1B1,SDHA,PAIP2,PHC2,CRKL,TERF2IP,ZNF75D,SHC1,UCHL5,NAA35,TMBIM1,CCT2,CDKN2AIP,MKLN1,HMGN4,GALK2,CDC23,SHCBP1,AP4E1,PRDM11,VEZF1,PPP2R5A,ACYP1,STAT1,PPA2,TRIM32,RHEBL1,C1orf112,TCF3,MRI1,BRAP,AGPAT3,MYNN,RAB11A,REEP5,FOXO3,MAD2L2,CCDC28A,PIP5K1C,RBM17,MAT2B,PTEN,CENPJ,OSTC,CREB1,PACS2,NCOA2,SMC4,NEK7,NET1,PARP4,TBRG4,ANAPC2,SGSH,HGS,TTLL4,SLC38A7,MFAP1,CCDC69,BRWD3,ESYT2,SKA3,NPHP4,UBE2E2,HNRNPAB,PLXNC1,ST13,TMEM184B,DNAJC24,ZNF107,KIF2C,SLC29A1,AGFG1,SIRT2,FKBP2,USP48,SNRPD3,UBQLN2,CUTC,EDC3,UBLCP1,ZNF804A,RAP1A,THADA,EIF4A3,AP3S2,ATG3,DPYSL2,PPP1R12C,AKR1B1,NDUFB9,JOSD1,RP2,TTC4,TECR,ARID4A,FGFR1OP2,TIMM50,TDP1,DPM1,FOPNL,SLC16A7,WDR82,SLC25A22,STK17B,DHX15,CHAF1A,GEMIN5,COPS6,SASS6,RPS26,PSMC1,SLC12A7,TBC1D12,TM9SF4,ZNF768,MED13L,TIA1,MEF2A,EPHX2,PITHD1,RHBDD1,NFATC3,ZNF335,BUD31,YBX1,KNTC1,ACAD8,UBE3C,ZNF189,ALDH9A1,KDELR1,CIC,OXR1,SEPT7,NAP1L1,ODF2,EXOC4,KIAA1328,NUP62,PITPNA,NAA20,PTDSS1,PDSS2,C7orf26,IMMT,ASH1L,CHERP,WDYHV1,PLAGL2,CHKB,IRF3,TWF2,PAIP1,ANKRD28,ANKLE1,FARSA,SAR1A,SCAMP4,APOOL,PDIA6,ACSL5,TOR1AIP2,AZI2,GFER,RAD54B,TMEM41A,DAP3,ZNF317,GADD45B,AKNA,REEP4,CBX4,KIF3B,GOLPH3L,SH2D3A,CASP6,TOR3A,SRGN,DBF4,MFSD10,SAC3D1,CTNNBL1,YIF1B,CLDND1,TTC17,SLC25A1,GINS1,CSNK1G2,TELO2,ADAM17,HMGN1,NASP,ASPM,PPP1R21,PRKAR1B,SYMPK,TARS,SNRPA,MAPK3,HLA-B,ATAD2,PLAA,ZNF330,OSBPL8,KBTBD7,PREPL |
| 2.068e-05 | -10.79 | SQSTM1 (sequestosome 1) | protein interactions | 8878 | 263 | 69 | 17029 | 2761 |
NDUFA5,CYLD,ATXN3,CUL1,RRAGC,CSNK2A1,DAZAP2,CCNB1,MAP1LC3B,MAPK14,SDHA,EPM2A,RAD23A,HNRNPA2B1,PSMA6,PIK3R2,HADHB,TARDBP,RNF26,DVL2,KCNAB2,MLST8,CDC37,VHL,CUL3,CHMP2B,ZFAND5,TOLLIP,CHAF1A,OPTN,RPL37,HSPA4,SMAD2,PEX5,PSMD3,FUS,SMAD1,SASS6,MAPK1,SMURF1,SMAD4,TWNK,UBXN1,TKT,PAWR,AKT1S1,CSNK1A1,GFM2,KIF5B,BCL2,GEMIN4,NSUN4,TMX1,EEF1D,NIPSNAP1,TXNL1,LDHA,WDR81,ISG15,FAS,KEAP1,OSBPL8,GLG1,PML,YWHAZ,NR2F2,PARP10,NIPSNAP2,IFI16 |
| 2.074e-05 | -10.78 | GO_REGULATION_OF_PROTEIN_MODIFICATION_PROCESS | MSigDB lists | GO_REGULATION_OF_PROTEIN_MODIFICATION_PROCESS | 1638 | 306 | 17377 | 2626 |
FGFR1OP,TXN,TSC2,KDM4A,XIAP,CUL1,CCNL2,CCNB1,PPP1R16B,PARK7,FBXO22,EEF2K,CDK5,CALM2,CDKN2C,PSMD1,FIZ1,FNIP2,CRY2,CDC25B,PLCL2,DNMT1,MLST8,BAK1,AKT2,PBK,TOPORS,DCUN1D5,IWS1,MAP3K4,BRMS1,HHEX,RPS27A,PSMD8,LIMK1,AXIN1,ITGB1,OGT,ARRB2,PDCD4,HDAC2,SVIP,PPIB,HSPH1,GMFG,CLSPN,PHF23,PRKAA1,GADD45G,EIF2AK4,PSEN1,PSMD9,WDR48,NDUFS4,DDRGK1,TFAP4,FKBP1A,FBXO7,MVP,GNAI2,PPP6R1,SOCS5,MAPKAPK3,RB1CC1,ZMYND11,GTPBP4,ADRB2,PTTG1IP,KDM3A,MAP2K2,PSMB3,AKAP1,FAS,DERL1,HSPBP1,FNTA,GOLGA2,CSK,DUSP3,FAM83D,PPP6R3,MAP3K5,CDK2,RNF139,ALS2,CDKN2A,PPP1R37,RAF1,MAGED1,RAC1,TPX2,CREBL2,PRKACA,APP,CRKL,TERF2IP,CCNA2,SHC1,RALB,MTA1,ADCY9,SOCS6,CDKN1B,ANAPC7,MAVS,GPD1L,CDK12,PDCL3,ADCY7,ANKLE2,PSRC1,BRD4,EID1,MAP4K4,TAOK1,WBP2,CUL3,ELP4,CDCA2,DNAJA1,PKMYT1,CDC23,RAB1A,PSMB9,SOCS7,PPP2CA,CDC16,PPP2R5A,CORO1C,HIPK2,RPLP1,TICAM1,PPP5C,GEN1,LRP8,CSNK1D,ZFP91,MECP2,FLOT1,AKT1S1,BLM,MAD2L2,CCNK,PSMD2,PDCD10,PTEN,PTPN11,AXIN2,FEM1B,MAP3K14,PDPK1,TNFAIP3,KAT2A,JTB,ANAPC2,ZP3,MARK2,PRDX1,SH3BP5,HGS,GPS2,PML,PPP1R11,PSAP,CD81,PARP10,IGBP1,ANAPC4,FAF1,CCNC,ZBED3,UBN1,NF1,FAM129A,PPP1R15B,ENSA,NENF,SIRT2,S1PR2,MAPK14,BIRC2,FANCI,PRNP,ZER1,RAP1A,CDC42,IL6ST,NOC2L,CDC37,COPS8,PLK1,NCK1,GMFB,EZR,CDC6,LRP5,BRCA1,SOX4,PAF1,SOCS4,ADAM9,CAB39,ZNF268,STK11,DVL1,ROCK1,CLU,CHEK2,PSMC1,ZCCHC9,PPP1R2,PPP1R12A,PHB2,GORASP1,DNAJB2,UBXN1,CIB1,CTCF,RGS2,RB1,ZNF335,CTR9,MDFIC,BCL2,GBA,PSMA1,EIF2AK1,MAP4K3,RTF1,KRAS,ISG15,PSMC4,MASTL,TSC1,MBIP,CDC27,SIAH2,NUP62,RUVBL2,EHD4,BCCIP,PRKAB1,ASH1L,TRAF7,FOXM1,DUSP22,LYN,UBXN2A,PSMA6,KIF14,PIN1,PPME1,AKAP8,TARDBP,CHTOP,F2R,CTDSP2,ABI1,STRAP,DVL2,SNX25,TIMP2,BIRC3,PSMA8,PSMB7,TOLLIP,DNAJC10,TAB2,PSMD3,STK38,GADD45B,XRCC3,SMURF1,MAPK1,PPP2R2D,SMAD4,PARD3,MIF,TRIP12,PAWR,DCUN1D4,FBXO5,PTPN2,FGFR3,ARHGEF2,BRD7,H2AFY,STAT3,TGFB1,TELO2,ADAM17,RHOA,PRKDC,PRKAR1B,WDR81,MEN1,SYMPK,HSPA1B,MAPK3,LEMD2,OSBPL8,PKD2,NR2F2,UBE2C,HRAS,HIPK3 |
| 2.079e-05 | -10.78 | COPB2 (coatomer protein complex subunit beta 2) | protein interactions | 9276 | 55 | 22 | 17029 | 2761 |
TELO2,UNK,COPA,TRIP10,COPE,WBP2,CUL3,BRCA1,RGS2,RUFY1,COPG2,COPB2,TMED10,HUWE1,DDA1,UBA5,ZNF746,PPM1G,LMAN1,MCPH1,TUBB,CDC5L |
| 2.083e-05 | -10.78 | PSRC1 (proline and serine rich coiled-coil 1) | protein interactions | 84722 | 18 | 11 | 17029 | 2761 |
CDKN2AIPNL,ATXN3,SRGN,PRDX5,KIF22,RNASEH2A,FUS,PRMT2,IGBP1,REEP5,APP |
| 2.083e-05 | -10.78 | DER_IFN_BETA_RESPONSE_UP | MSigDB lists | DER_IFN_BETA_RESPONSE_UP | 101 | 32 | 17377 | 2626 |
DNAJC2,HLA-E,RHOC,TAP1,AP3M2,CYCS,HLA-A,ATP6V0B,HADHB,PTPN11,CTR9,TRIM14,PPP3CA,GMFB,PARP4,BCLAF1,PSMB9,EIF3A,ISG15,DDX17,EPRS,TRIM26,ETS2,RBMX,STAT1,ADAM9,PDXK,PPP5C,RBBP4,SMAD4,IFI16,FUBP1 |
| 2.083e-05 | -10.78 | GCM_CALM1 | MSigDB lists | GCM_CALM1 | 101 | 32 | 17377 | 2626 |
WSB2,KDM3B,KIF3B,SNX27,CLCN3,EXOSC6,ZNF84,TSPYL4,MAP4K4,ACSL3,ADO,WBP2,LANCL1,NCKAP1,ATP6V1B2,FOXO3,ZNF275,CAND1,DDX17,ZER1,CRKL,MOAP1,NAPG,PDXP,FBXO21,EIF4ENIF1,ASAP2,VPS26B,MTMR4,PPME1,TNPO2,PREPL |
| 2.090e-05 | -10.78 | PHAX (phosphorylated adaptor for RNA export) | protein interactions | 51808 | 44 | 19 | 17029 | 2761 |
PDPK1,NIFK,EWSR1,RPS6KA1,GADD45G,CUL3,DDX20,CAND1,RAD23A,VAV1,MKNK1,UBXN2A,KPNA1,HUWE1,NSFL1C,SNRNP70,FBL,REEP4,SSRP1 |
| 2.091e-05 | -10.78 | MTA2 (metastasis associated 1 family member 2) | protein interactions | 9219 | 129 | 40 | 17029 | 2761 |
UNK,TSC22D3,SUMO2,TOP2B,TCF19,HMG20A,PARK7,MTA1,MBD2,BANF1,PPP4R1,RTCB,UBE3C,DNMT1,ZNF800,HNRNPM,SAP30,RPP25,PHF20L1,CUL3,LSM8,NFATC2,BRCA1,MBD3,APPL1,TRIM28,FKBP3,POLR2A,KPNA1,CHD3,HNRNPR,MAP4,APPL2,CCDC69,KPNA2,YY1,RBBP4,NIPSNAP2,HDAC2,PTOV1 |
| 2.091e-05 | -10.78 | EEF1A2 (eukaryotic translation elongation factor 1 alpha 2) | protein interactions | 1917 | 129 | 40 | 17029 | 2761 |
CYLD,TCF3,DBF4,CUL1,PITHD1,HAUS2,CDC73,WWP2,RPA2,HOMER1,PSMD1,PTEN,MCM5,EFTUD2,CRY2,AHCY,RNF26,TTLL12,PABPC1,EEF1D,CDC37,CUL3,GORASP2,PKM,MCM2,RAB1A,DHX57,POLR2A,ISG15,RPSA,CAND1,RPA1,SLC38A7,MAPK6,MIA2,ACTB,STK11,COPS6,ARRB2,CD81 |
| 2.102e-05 | -10.77 | PPME1 (protein phosphatase methylesterase 1) | protein interactions | 51400 | 99 | 33 | 17029 | 2761 |
KARS,ANXA6,TSTA3,WDR1,CAST,MDH2,ERO1A,TKT,ENSA,LDHA,HNRNPF,EZR,AGFG1,PKM,TMEM165,TRIM28,LMNA,RPA1,PPP2CA,PCNA,HSPBP1,PDCD10,PPME1,WDR4,OGT,GPI,TTLL12,LRSAM1,RPRD1B,PPP2R2D,EEF1D,NUDC,LDHB |
| 2.102e-05 | -10.77 | HNRNPA0 (heterogeneous nuclear ribonucleoprotein A0) | protein interactions | 10949 | 99 | 33 | 17029 | 2761 |
HNRNPAB,DHX9,CUL1,LMNA,RPA2,EIF4A3,TARDBP,HNRNPM,STAU1,HNRNPF,CUL3,CIRBP,SRSF5,BRCA1,EIF4H,MATR3,ABCF1,RPSA,CAND1,RPA1,SRSF1,SYNCRIP,HNRNPR,HNRNPH3,RBMX,PSMD8,MAPK6,COX5A,DDX5,SRSF3,HNRNPDL,SMURF1,ARRB2 |
| 2.108e-05 | -10.77 | GSE37301_GRANULOCYTE_MONOCYTE_PROGENITOR_VS_RAG2_KO_NK_CELL_UP | MSigDB lists | GSE37301_GRANULOCYTE_MONOCYTE_PROGENITOR_VS_RAG2_KO_NK_CELL_UP | 171 | 47 | 17377 | 2626 |
CTU2,UBE2E2,ATXN3,ANXA6,WDYHV1,WDR13,CUTA,CUL1,ASAH1,PTP4A3,SLC4A2,ADPGK,TMED3,NANS,ETS1,RAB11A,KTN1,SLC25A37,USP5,UBE2Q2,SMC3,ZNHIT6,MAST2,ATF2,SLC12A2,NDUFA3,TMBIM1,CSNK1G3,PDCL3,LDHB,PLK1,PPP1R21,E2F3,FBXO9,MCFD2,PTTG1IP,NCDN,DDX17,TMEM184C,SERTAD2,CDC16,SYNCRIP,GOLGA2,CDC27,RPL32,TOMM6,SLC16A1 |
| 2.110e-05 | -10.77 | GEMIN7 (gem nuclear organelle associated protein 7) | protein interactions | 79760 | 37 | 17 | 17029 | 2761 |
ADD1,SNRPB,TAOK1,DDX20,SNRPD3,EDRF1,GEMIN5,GOLM1,SHC1,RPLP1,SLC25A19,GEMIN6,XRCC3,GEMIN4,SNRNP70,STRAP,CSNK1D |
| 2.110e-05 | -10.77 | RBM45 (RNA binding motif protein 45) | protein interactions | 129831 | 37 | 17 | 17029 | 2761 |
RBM42,MEMO1,CUL3,ATP5MF,KIF11,USP21,CAND1,DOT1L,FANCL,KEAP1,CTNNBL1,RBMX,PPM1G,TARDBP,KIF22,DEF6,CDC5L |
| 2.119e-05 | -10.76 | Golgi-associated vesicle membrane | cellular component | GO:0030660 | 112 | 34 | 18223 | 2701 |
TMED7,COPA,HLA-E,GPR89A,COPE,SCYL1,VTI1A,TMED3,SEC16A,SYNRG,COPG2,HLA-A,COPB2,SPPL2A,CD59,SAR1A,SEC24C,ZDHHC13,LMAN1,CLTB,TMED2,KDELR1,USO1,GOPC,MCFD2,PEF1,SPPL2B,SEC31A,HLA-B,PDCD6,SEC23IP,SCAP,TMED10,AP1S1 |
| 2.121e-05 | -10.76 | transcriptional repressor complex | cellular component | GO:0017053 | 85 | 28 | 18223 | 2701 |
SP3,NCOR2,ETV3,DEPDC1,BAZ2A,MTA2,MIER1,CSNK2A1,RCOR1,DDX20,SIRT2,RCOR3,MBD3,APPL1,LIN9,TFAP4,GPS2,CHD3,JAZF1,APPL2,RBPJ,RBBP4,SMARCE1,TNRC18,ARID4A,HDAC2,N4BP2L2,RLIM |
| 2.135e-05 | -10.75 | WANG_METASTASIS_OF_BREAST_CANCER_ESR1_UP | MSigDB lists | WANG_METASTASIS_OF_BREAST_CANCER_ESR1_UP | 19 | 11 | 17377 | 2626 |
YIF1A,PLK1,ATAD2,ZCCHC8,GTSE1,KPNA2,TMEM8A,SUPT16H,CBX3,POLQ,SMC4 |
| 2.135e-05 | -10.75 | ABRAHAM_ALPC_VS_MULTIPLE_MYELOMA_DN | MSigDB lists | ABRAHAM_ALPC_VS_MULTIPLE_MYELOMA_DN | 19 | 11 | 17377 | 2626 |
CDK5,TGFB1,TXN,PTEN,IL6ST,TCF3,CCNB1,PSEN1,XRCC4,XRCC5,CDC37 |
| 2.153e-05 | -10.75 | lung-carcinoma-undifferentiated_carcinoma | COSMIC cancer mutations | lung-carcinoma-undifferentiated_carcinoma | 1421 | 266 | 17385 | 2587 |
FGFR1OP,ZBTB10,MAX,TSC2,XIAP,USP39,MYEF2,FBXO22,EEF2K,NUP153,CDC25B,TFG,TIPARP,DNMT1,SENP1,USP34,BAK1,ERCC1,NRAS,AKT2,USP22,AURKB,CCNF,CBFB,TRIM47,WAS,SMAD2,RAD18,AXIN1,ITGB1,TRAF5,ARRB2,ZNF598,HDAC2,EWSR1,RHOC,PRKAA1,VAV2,RAB23,NOTCH2,APH1B,PSEN1,CDC73,MEX3C,ZNRF2,ATIC,MSH2,SOCS5,MFNG,USP10,RIT1,ADRB2,ELK1,RHOB,FAS,XRCC5,ETS2,ERGIC3,PIAS2,USP32,VCPIP1,NDE1,MAP3K5,CDK2,CABLES1,CDKN2A,ABCA3,ATXN3,DNMT3A,RAF1,SUZ12,RAC1,BCL2L1,PRKACA,KTN1,ANKIB1,REPS1,CCNA2,FBXL6,SHC1,KDM2A,RALB,UCHL5,ZCCHC2,SOCS6,CDKN1B,TTC3,RNASEH2A,RBM15,ATF2,CDK12,SHOC2,BRD4,ERF,ELP4,PKMYT1,MEF2D,ERC1,TRIM28,PPP2CA,RAD51C,PPP2R5A,JAK1,STAT1,FUS,EYA2,POLQ,RHEBL1,PRPF4B,USP13,OTUD5,TCF3,BRAP,BLM,IL21R,ETS1,FOXO3,MAD2L2,NEIL2,WWP2,RFWD3,CAPN2,PDCD10,PTEN,AXIN2,PTPN11,LTN1,UBE3B,CREB1,FBXL19,NCOA2,MSH6,PDPK1,TNFAIP3,KAT2A,KLF6,MARK2,PICALM,FADD,KEAP1,CCDC6,WNT5B,MAPK6,PML,PPP1R11,RGL1,PARP10,YWHAH,DDB1,NF1,TRIM11,CSNK2A1,S1PR2,USP48,MAPK14,BIRC2,FANCL,ABL2,RAP1A,CDC42,JAZF1,ETV6,XRCC2,PIK3R2,JOSD1,TCEA1,OGG1,CDC37,PLK1,SEPT9,CELSR2,APH1A,NCK1,VHL,LRP5,CDC6,BRCA1,USP21,RHEB,FBXO28,SOCS4,STK11,CHEK2,DVL1,COPS6,NUMB,PARP12,LAMTOR3,PCSK7,MEF2A,THRAP3,RAPGEF6,RB1,XPA,BCL2,ZRANB1,UBE3C,MAML1,CIC,KRAS,SDHB,GNAS,MBIP,TSC1,PCM1,PALB2,YWHAZ,NUP62,USP7,TCF12,PRKAB1,CYLD,TRAF7,PMS2,EXT2,USP5,VAV1,MDM2,ABI1,DVL2,POU2AF1,BIRC3,SLC26A6,FANCE,USP36,EIF3H,STAT6,STK38,UHRF2,H3F3A,USP11,MAPK1,SMURF1,SMAD4,USP53,ABCA1,TRIP12,CASP6,CHIC2,CSNK1A1,FZD6,FBXO5,HERC3,KIF5B,IRF4,FGFR3,SS18L1,STAT3,TGFB1,HMGN1,RHOA,ADAM17,ARHGEF12,PCGF1,MEN1,MAPK3,TFEB,ATP6V1D,FBXO41,BIRC5,NEIL3,TFE3,DTX4,USP20,RBPJ,HRAS |
| 2.155e-05 | -10.75 | ZHAN_MULTIPLE_MYELOMA_PR_UP | MSigDB lists | ZHAN_MULTIPLE_MYELOMA_PR_UP | 43 | 18 | 17377 | 2626 |
MCM10,FOXM1,ASPM,TPX2,CCDC34,RRM2,RACGAP1,NUSAP1,NUF2,CCNB1,FANCI,SLC19A1,BIRC5,KIF14,PRC1,KPNA2,UBE2C,CCNB2 |
| 2.155e-05 | -10.75 | GNF2_ELAC2 | MSigDB lists | GNF2_ELAC2 | 43 | 18 | 17377 | 2626 |
DDX47,SNRNP200,ZCCHC8,HNRNPF,PSMA1,DHX15,SRSF1,RPA1,SF3B2,HSPB11,HNRNPR,RBMX,U2SURP,BANF1,NUP62,TARDBP,HNRNPM,SRSF10 |
| 2.155e-05 | -10.75 | MODULE_125 | MSigDB lists | MODULE_125 | 43 | 18 | 17377 | 2626 |
RFC3,PRIM2,CENPF,RRM1,RRM2,ORC1,BLM,RFC2,CHAF1A,RPA1,PRIM1,RPA2,NAP1L1,PCNA,POLE,RNASEH2A,RBBP4,CDK2 |
| 2.161e-05 | -10.74 | GSE17974_2H_VS_72H_UNTREATED_IN_VITRO_CD4_TCELL_UP | MSigDB lists | GSE17974_2H_VS_72H_UNTREATED_IN_VITRO_CD4_TCELL_UP | 176 | 48 | 17377 | 2626 |
CORO7,PHF23,TRMT6,GADD45G,ZNF416,PLXNA1,MXD4,BRIX1,RAPGEF6,CHD1,PRNP,LYAR,TIMM23,LRRC8D,ATP6V0A2,ARHGEF2,UBE3C,EIF5,ASB6,ZNF583,ATP6V1G1,METTL1,FYTTD1,SAMD4B,DDX28,KLF10,CYP20A1,UTP15,FAM133B,UTP3,SLC17A5,AP4E1,ARMC8,TMEM201,VEZF1,PON2,FBXO21,PLAA,SYNCRIP,RBM25,HPS5,FAM3C,ZNF268,SMAD1,ZNF45,SMURF1,FAM83G,ZSWIM6 |
| 2.177e-05 | -10.73 | GSE7596_AKT_TRANSD_VS_CTRL_CD4_TCONV_WITH_TGFB_UP | MSigDB lists | GSE7596_AKT_TRANSD_VS_CTRL_CD4_TCONV_WITH_TGFB_UP | 152 | 43 | 17377 | 2626 |
UBL3,ANKRD13D,CYLD,TRIP12,MTX3,RWDD1,IVNS1ABP,ACTR3,MYNN,BLM,CDK11B,ELMOD2,RNF103,CDKN2C,RB1,APLP2,MDM2,WDR44,CENPJ,RABGAP1L,IL6ST,PHF14,ZCCHC2,CLDND1,RHBDD2,ADCY7,GINS1,TK1,OXR1,NOL8,PNPLA8,SEPT7,SHCBP1,KIF11,ALKBH6,KBTBD7,BAZ1B,RUFY3,ESPL1,CSNK1D,N4BP2L2,ADNP2,DDX42 |
| 2.177e-05 | -10.73 | GSE10147_IL3_VS_IL3_AND_CPG_STIM_PDC_DN | MSigDB lists | GSE10147_IL3_VS_IL3_AND_CPG_STIM_PDC_DN | 152 | 43 | 17377 | 2626 |
ABCA3,GOLPH3L,DHPS,ZDHHC8,HABP4,CTCF,NIT2,PLXNA1,EZH1,SEC16A,TUBGCP2,KIF5B,CWC27,ZKSCAN1,LPIN2,NUP107,KIFAP3,AQR,ZRANB1,ORC3,GTF2H2,OGG1,PPP6R1,CSTF1,KDM3B,ATG9A,HELB,RAB7A,EMB,TYW1,ARHGEF12,RAB3IP,TRIM28,LSG1,MTHFD2,TXNDC16,ZHX1,PPP6R2,CCDC125,WDR91,GCSH,PFKP,ANXA11 |
| 2.178e-05 | -10.73 | antigen processing and presentation of exogenous antigen | biological process | GO:0019884 | 180 | 49 | 17256 | 2622 |
KIF3B,HLA-E,DYNLL1,DCTN2,TAP1,KLC1,KIF23,RACGAP1,ARF1,KIF2C,AP1B1,ITGB5,PSMD9,HLA-A,PSMD2,CTSS,PSMA6,PSMD1,SEC24C,CAPZA1,DNM2,AP1M1,AP2B1,KIFAP3,KIF22,TAP2,DCTN1,PSMA8,RAB7A,PSMB7,KIF15,PSMA1,CAPZA2,PSMB9,KIF11,PSMB3,PSMC4,KIF2A,SEC31A,CTSL,HLA-B,KIF18A,PSMD8,PSMD3,SNAP23,AP1S1,AP2S1,PSMC1,DYNC1LI2 |
| 2.180e-05 | -10.73 | CHICAS_RB1_TARGETS_SENESCENT | MSigDB lists | CHICAS_RB1_TARGETS_SENESCENT | 528 | 115 | 17377 | 2626 |
TMEM106C,GXYLT1,LUZP1,CKLF,IVNS1ABP,SF3B1,FAM129A,TMEM97,SLC20A1,FANCI,SLC25A37,ARL6IP6,MBD4,FANCL,APLP2,PRKD3,PCNA,SP100,TNFAIP8,CDC42,IL6ST,DUT,TTC3,CISD2,MAST2,RNASEH2A,MCMBP,ANKRD9,ERCC1,RHOBTB3,BIRC3,SNRPB,RRM2,SLBP,WDHD1,NUSAP1,MCL1,CDC6,MCM2,RFC2,ODC1,PRIM1,DPYSL3,HSPB11,DSN1,ACYP1,CERS6,ZNF367,HIPK2,MAP4,GLCCI1,TSPAN5,GCLM,NSMCE4A,SESTD1,MRI1,CDT1,RRM1,SMC6,PAWR,THRAP3,LANCL1,RMI1,HAUS2,SAC3D1,SLC25A36,DTL,RFWD3,SMC3,ADD3,CTSS,MCM5,FUT8,MEA1,MSH2,H2AFY,FBL,NUP85,MSH6,GINS1,AGGF1,NASP,TNFAIP3,DDX24,NET1,NQO2,PRKDC,OXR1,RDH10,KRAS,SEPT7,C9orf40,COMMD4,MTR,CYB5A,ISG15,RPA1,HMGN2,HLA-B,SLCO4A1,FBXO21,ATAD2,TMEM54,OSBPL8,DCK,CDCA7L,PRPS2,BBX,ACADM,WDR76,YY1,NDE1,RBBP4,CDK2,S100PBP |
| 2.188e-05 | -10.73 | GO_GOLGI_CISTERNA | MSigDB lists | GO_GOLGI_CISTERNA | 88 | 29 | 17377 | 2626 |
MOB4,NAGPA,B3GALT6,GOLIM4,TMEM115,GOLPH3L,APH1A,B4GALT5,B4GALT1,TMED3,B4GALT4,STX16,GOSR1,BCAP31,HLA-A,NUCB1,RAB21,ASAP2,GALNT2,GOLGA2,GOLGA8A,FUT8,ARAP1,CANT1,ST3GAL2,B4GALT3,CHPF2,TMED2,B4GALT2 |
| 2.192e-05 | -10.73 | centrosome cycle | biological process | GO:0007098 | 79 | 27 | 17256 | 2622 |
PLK1,KIF3B,PPP1R12A,TUBGCP5,HAUS4,CNTROB,BRCA1,KIF11,HAUS2,TUBGCP2,HAUS8,PCM1,CCP110,GOLGA2,CHD3,CENPJ,ODF2,XRCC2,SLC16A1,NUP62,PKD2,CEP63,NDE1,WDR62,SASS6,CDK2,DCTN1 |
| 2.193e-05 | -10.73 | histone H3-K4 methylation | biological process | GO:0051568 | 32 | 15 | 17256 | 2622 |
TET3,ASH1L,SETD3,CXXC1,ZNF335,OGT,KMT2B,CTR9,RTF1,WDR82,BEND3,WDR5,KMT2C,RLF,ARID4A |
| 2.193e-05 | -10.73 | mitotic spindle | cellular component | GO:0072686 | 94 | 30 | 18223 | 2701 |
BCCIP,PKP4,KAT2A,ASPM,DYNLL1,RAE1,TPX2,KIF23,CKAP2L,RACGAP1,RANGAP1,NUSAP1,AURKB,SIRT2,KIF11,SPAG5,KIFC1,KIF18A,SMC3,CDC42,KIF18B,GOLGA2,MAP4,FAM83D,NUP62,KIF22,PKD2,MAPK1,ESPL1,TACC3 |
| 2.195e-05 | -10.73 | NDUFS1 (NADH:ubiquinone oxidoreductase core subunit S1) | protein interactions | 4719 | 95 | 32 | 17029 | 2761 |
RPS15,COX15,NDUFV2,TNFAIP3,MDH2,TMEM126B,RAB7A,METTL2A,CUL3,NDUFA4,ATP5F1B,TOMM40,MCM2,VDAC1,RHOT2,RAB5B,GNB2,NDUFS7,NDUFS4,SDHB,NDUFV1,ATP1A1,SEC24C,NDUFA11,PML,NDUFB9,NDUFS8,NDUFS5,TECR,MRPL13,ATP6V0D1,FGFR1OP2 |
| 2.195e-05 | -10.73 | STX7 (syntaxin 7) | protein interactions | 8417 | 95 | 32 | 17029 | 2761 |
PPIF,SARNP,TM9SF4,GORASP1,VPS45,VDAC2,RNPS1,TMEM216,VTI1A,ADPGK,NDUFA7,PTTG1IP,RAB1A,STX16,GOSR1,GLMP,LMNA,SUGP1,SLC31A1,NAPG,GOLGA2,NSF,ZKSCAN1,SNAP29,SNAP23,ADCY9,TYW5,MAPK6,STX18,RBMS1,CLDND1,EHD4 |
| 2.203e-05 | -10.72 | Pqbp1 (polyglutamine binding protein 1) | protein interactions | 54633 | 24 | 13 | 17029 | 2761 |
SART1,SNRNP200,LSM6,MFAP1,DENND4C,EFTUD2,SMU1,TOPORS,PRPF4,PRPF3,TOP1MT,CFAP20,ASF1B |
| 2.207e-05 | -10.72 | GSE12845_IGD_NEG_BLOOD_VS_DARKZONE_GC_TONSIL_BCELL_UP | MSigDB lists | GSE12845_IGD_NEG_BLOOD_VS_DARKZONE_GC_TONSIL_BCELL_UP | 181 | 49 | 17377 | 2626 |
IER2,PPIB,CTDP1,TMEM184B,PLXNC1,SCAMP3,HLA-E,WDR13,UFC1,TRIO,TMEM109,UCK2,BTN3A1,CLCC1,APH1B,ABHD14A,RSAD1,HLA-A,CFLAR,SUB1,RPN1,DECR1,FAM89B,RPN2,TAGLN2,MAVS,SPSB3,NAGPA,USO1,PBXIP1,NUDT4,SELPLG,GNG7,ITM2A,DIDO1,SERP1,YIF1A,MAGED2,EPRS,HINT1,SEC61A1,CERS6,FASTK,FTSJ1,IMPDH1,SIL1,PPP1R11,PDXK,MAP3K5 |
| 2.207e-05 | -10.72 | GSE27786_LSK_VS_CD8_TCELL_UP | MSigDB lists | GSE27786_LSK_VS_CD8_TCELL_UP | 181 | 49 | 17377 | 2626 |
TMEM106C,BCL2L12,PIGN,TXN,TMBIM4,TRAK1,CUL1,EIF2AK4,PDCD7,NCAPG,MAPK14,STAM,SRRT,CPNE3,MOAP1,COQ4,ZKSCAN1,GOT2,MCM5,LPIN2,KIFAP3,CITED2,LPCAT1,C12orf75,TACC3,B3GALT6,TELO2,NTPCR,ACSL3,CCDC34,CDCA2,CCNF,TOLLIP,GLOD4,MOSPD3,TRIM47,KIF18A,HAGHL,ADAM9,NUP62,CHEK2,MBD6,TMEM159,CDK2,HEXA,C11orf1,ARHGAP23,GCSH,PTOV1 |
| 2.207e-05 | -10.72 | GSE3982_CTRL_VS_LPS_4H_MAC_UP | MSigDB lists | GSE3982_CTRL_VS_LPS_4H_MAC_UP | 181 | 49 | 17377 | 2626 |
ASH1L,MPHOSPH8,TM9SF4,GNPDA1,DYNLL1,TMX4,AP3M2,PCSK7,TOP2B,KIF2C,RUFY1,TTF1,REPS1,GIT2,RNF103,EPM2A,PHC2,CLUAP1,ZNF473,NVL,PPP1R8,PPME1,MRPS27,SS18L1,AQR,SLC35A1,ILKAP,CSNK1G2,BRD4,RFC3,ERF,NCK1,KAT7,FRAT2,BCLAF1,AURKB,CDC23,ICMT,CBFB,ARHGAP15,C19orf54,SEC61A1,ARNTL,MEGF9,ZMIZ1,E2F2,PDSS2,RPS26,POT1 |
| 2.207e-05 | -10.72 | GSE27786_BCELL_VS_MONO_MAC_UP | MSigDB lists | GSE27786_BCELL_VS_MONO_MAC_UP | 181 | 49 | 17377 | 2626 |
OTUD5,BCL2L12,RWDD1,PHB2,PHF23,DYNLL1,SCYL1,CTCF,NKRF,NENF,OAT,IFT27,ZADH2,WRNIP1,SF3B2,ABL2,NDUFV1,PSMA6,RPL17,DNAAF2,PHF14,LPIN2,CABLES2,CREB1,ZNRD1,NAA35,RPL22L1,USP34,TSHZ1,POLR2G,DDX24,GMFB,DNAJC9,BCLAF1,FXR1,KDM1B,PRPSAP1,TTC33,EIF3G,POLR2A,SOCS7,CAT,UBTF,PON2,TIMM13,PSMD3,ARNTL,GCSH,IPO4 |
| 2.226e-05 | -10.71 | antigen processing and presentation of peptide antigen | biological process | GO:0048002 | 185 | 50 | 17256 | 2622 |
KIF3B,HLA-E,DYNLL1,DCTN2,TAP1,KLC1,KIF23,RACGAP1,ARF1,KIF2C,AP1B1,ITGB5,PSMD9,BCAP31,HLA-A,PSMD2,CTSS,PSMA6,PSMD1,SEC24C,CAPZA1,DNM2,AP1M1,AP2B1,KIFAP3,KIF22,TAP2,DCTN1,PSMA8,RAB7A,PSMB7,KIF15,PSMA1,CAPZA2,PSMB9,KIF11,PSMB3,PSMC4,KIF2A,CTSL,SEC31A,HLA-B,KIF18A,PSMD8,PSMD3,SNAP23,AP1S1,AP2S1,PSMC1,DYNC1LI2 |
| 2.231e-05 | -10.71 | CTDP1 (CTD phosphatase subunit 1) | protein interactions | 9150 | 59 | 23 | 17029 | 2761 |
POLR2G,PRKDC,SNRPB,CSNK2A1,NUF2,POLR2A,GTF2F1,IWS1,PPP2CA,ERH,MED8,DSN1,ETS2,POLR2J,INTS7,INTS1,STK38,MED15,E2F1,LTN1,TCEA1,SNRNP70,RPRD1B |
| 2.237e-05 | -10.71 | NGLY1 (N-glycanase 1) | protein interactions | 55768 | 21 | 12 | 17029 | 2761 |
NAGPA,DERL1,TRAFD1,UBXN2B,RAD23B,NSFL1C,B4GALT4,GUCD1,APP,FAF1,SRPK2,RAD23A |
| 2.239e-05 | -10.71 | AP2B1 (adaptor related protein complex 2 subunit beta 1) | protein interactions | 163 | 112 | 36 | 17029 | 2761 |
COX5B,NUP54,EPN1,MYH9,XPO7,TFRC,PIP5K1C,UTP25,TERF2IP,RPA2,MEX3C,SHC1,SEC24C,MEA1,AP1M1,GTSE1,CLTB,ATP6V1G1,CUL3,RNPS1,NUSAP1,BRCA1,TOMM40,MCM2,ANLN,PICALM,RPA1,NECAP2,ODF2,CAB39,AP1S1,KPNA2,ARRB2,SMURF1,SMAD4,AP2S1 |
| 2.239e-05 | -10.71 | TMPO (thymopoietin) | protein interactions | 7112 | 112 | 36 | 17029 | 2761 |
USP7,UNK,PHB2,EYA1,SUMO2,SDC2,CSNK2A1,GMCL1,CHD1,LMNA,OIP5,RPA2,RB1,BANF1,RRBP1,CRY2,ATP6V0D1,SRPK2,CDC5L,HP1BP3,LARS,RPL35,KAT7,TMEM216,ILF3,CIRBP,NUSAP1,XRCC5,RPA1,UBTF,XRCC3,CLN3,ARRB2,SMURF1,CD81,PFKP |
| 2.239e-05 | -10.71 | Cdk1 (cyclin-dependent kinase 1) | protein interactions | 12534 | 112 | 36 | 17029 | 2761 |
PPP1R12A,ACTR3,CCNB1,AP3S1,SNAPC4,GNB2,CDK5,CCNA2,ARPC5,SEC24C,EFTUD2,CDKN1B,ANAPC7,GNAI2,GCC1,ZFP64,SNRNP200,NSUN2,EZR,ANAPC2,PKMYT1,CDC23,PKM,CCT8,PRDX1,ARF4,IDE,AHNAK,CDC27,CORO1C,SLC25A19,DDX5,TAF12,CCNB2,ESPL1,ANAPC4 |
| 2.246e-05 | -10.70 | GSE46606_IRF4MID_VS_WT_CD40L_IL2_IL5_DAY3_STIMULATED_BCELL_DN | MSigDB lists | GSE46606_IRF4MID_VS_WT_CD40L_IL2_IL5_DAY3_STIMULATED_BCELL_DN | 186 | 50 | 17377 | 2626 |
RECQL,ANKRD13D,CORO7,GNPDA1,WDYHV1,RPS6KA1,ZFP91,CIB1,CERK,TATDN3,VTI1A,EPN1,B4GALT1,ABCB10,MXD4,CCDC28A,FERMT3,STARD9,SH3BP1,FAM89B,CORO1A,LDLRAD3,SLC35C2,KCNAB2,MED22,PREB,ADCY7,CLPTM1,ZFP64,ACP2,FAM49B,PPT1,DCAF8,PPP1R21,KIAA0930,ABHD11,HAGH,NDRG3,NEU1,MYO1F,SDHB,SGSH,SERF2,APPL2,PDXK,ARRB2,TAF6,RTN3,SLC25A39,RHEBL1 |
| 2.246e-05 | -10.70 | GSE27786_CD4_TCELL_VS_NKCELL_DN | MSigDB lists | GSE27786_CD4_TCELL_VS_NKCELL_DN | 186 | 50 | 17377 | 2626 |
EXOC3,CDC40,NUP188,RAF1,TOR1AIP1,HEXB,SUMF1,SDF2L1,GGA2,MAPK14,RUFY1,NUP205,ARL6IP6,TMEM179B,ATP6V0B,MTMR4,ATG3,MAVS,TALDO1,MAML1,CNPY3,ABCC5,NAGPA,SMU1,MAP7D1,PLEKHM3,NUSAP1,MEF2D,ANLN,RFC2,ARSK,PICALM,TFEB,MKNK1,PPP2R5A,RBM47,GOLGA7,OSBPL8,SNAP23,HPS5,CTBS,DBI,KBTBD7,CRCP,FAM126A,YWHAZ,MAP3K5,NR2F2,SLC25A39,NXT2 |
| 2.246e-05 | -10.70 | GSE6674_CPG_VS_CPG_AND_ANTI_IGM_STIM_BCELL_UP | MSigDB lists | GSE6674_CPG_VS_CPG_AND_ANTI_IGM_STIM_BCELL_UP | 186 | 50 | 17377 | 2626 |
RMND5A,MBD1,GLT8D1,TXN,TOR3A,UROD,BABAM1,TAP1,CIB1,CDCA3,NDUFA4,PXMP2,KIF2C,ORC1,IFT27,BECN1,CCDC28A,PRPF18,SUB1,GATC,MTMR4,TTC9C,ABCD1,TAP2,TECR,TRAFD1,DDX24,CDC123,HARS,LACTB,WBP1,CCNF,NDRG3,COMMD4,PSMB9,ANKRD46,PRDX1,BTBD1,TAF2,TXNDC16,BIRC5,OAZ2,FAM3C,PML,PIAS2,MDH1,ANP32E,CHMP4B,MZT2B,ESYT2 |
| 2.246e-05 | -10.70 | GSE17186_NAIVE_VS_CD21LOW_TRANSITIONAL_BCELL_DN | MSigDB lists | GSE17186_NAIVE_VS_CD21LOW_TRANSITIONAL_BCELL_DN | 186 | 50 | 17377 | 2626 |
UBE2D3,TCF12,GMFG,ADD1,KRBA1,CCM2,WDTC1,PMS2,B4GALT1,SLC20A1,IL21R,MAT2B,NFATC3,PDCD10,SIAH1,NT5DC1,HDAC7,RCSD1,AXIN2,RPL22L1,TMEM9,TPCN1,SMC4,CYTH1,TIMP2,KIAA0040,DENND4C,HSDL1,UTP15,EZR,EMP3,POLR3GL,ESYT1,ICAM2,RPSA,SMAP2,USP36,RBM38,UTP20,PPP2R5A,JAK1,L3MBTL3,FAM3C,RNF38,SLC16A1,SLAIN1,SMG9,CBX4,DEF6,ESYT2 |
| 2.246e-05 | -10.70 | GSE2826_WT_VS_BTK_KO_BCELL_UP | MSigDB lists | GSE2826_WT_VS_BTK_KO_BCELL_UP | 186 | 50 | 17377 | 2626 |
UBL3,IER2,MRPL39,CXXC1,MECP2,TRIO,MRPS26,UCK1,IRF3,OAT,CRLF3,UBLCP1,USP5,BCAT2,C12orf10,IARS,TNFAIP8,DAD1,MCM5,CRAT,TIMELESS,H2AFY,CRY2,BCL2,RNASEH2A,MRPL48,PHKG2,PRRC2A,NEK7,LDHA,WIPF1,MCL1,PLEC,ICAM2,RAB5B,SLC50A1,EIF3G,PSMB3,ZFR,PRIM1,SLC19A1,CSK,QARS,DNAJC17,IARS2,SLC25A19,WIPI2,KLHDC4,DMWD,COPS6 |
| 2.246e-05 | -10.70 | GSE41978_WT_VS_ID2_KO_AND_BIM_KO_KLRG1_LOW_EFFECTOR_CD8_TCELL_UP | MSigDB lists | GSE41978_WT_VS_ID2_KO_AND_BIM_KO_KLRG1_LOW_EFFECTOR_CD8_TCELL_UP | 186 | 50 | 17377 | 2626 |
UNK,NSMCE4A,C19orf53,MRPS15,MECP2,FAM53C,TRIO,XIAP,FAM76A,LAGE3,RAB23,SUMF1,TCF19,STMN1,IFT27,MFSD10,MBD4,EEF2K,RFWD3,APLP2,CCNA2,TIMELESS,CENPM,PHF20L1,CREG1,TSPYL4,CAMSAP1,GMFB,KCTD20,DNAJC9,EXOSC9,BUD13,ZDHHC3,GINS4,ASF1B,PRIM1,SCARB2,KIF18A,BIRC5,RBL1,MFAP1,NEIL3,CDCA5,H2AFX,PGRMC1,SSNA1,UBE2C,GLCCI1,NUDT11,PDLIM5 |
| 2.253e-05 | -10.70 | CDK6 (cyclin dependent kinase 6) | protein interactions | 1021 | 125 | 39 | 17029 | 2761 |
MCM10,FOXM1,TRAK1,TPX2,FOXO3,CDKN2C,RB1,FGFR3,RBM23,NFATC3,PCNA,CCNA2,FBXO7,ZNF335,CDKN1B,TRA2B,CDC37,SRSF11,KLF10,VHL,ATXN1,SLBP,CDC6,EIF2AK1,MEF2D,ELK1,MCM2,ZNF174,SRSF1,ZMYM3,PPP2CA,EIF4ENIF1,RBL1,TFDP1,UHRF2,PML,FKBP5,CDK2,CDKN2A |
| 2.253e-05 | -10.70 | SMARCE1 (SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1) | protein interactions | 6605 | 125 | 39 | 17029 | 2761 |
EWSR1,TRIP12,TRIP10,ARID2,MECP2,BRAP,SMARCA4,TOP2B,ARID1B,HAUS2,SPAG5,TFAP4,MDM2,BANF1,TXLNA,BRD7,SS18L1,NUP153,CEP63,NCOA2,CARM1,PHF10,CUL3,RCOR1,NFATC2,PBRM1,ARID1A,CAND1,BRMS1,GOLGA2,TFE3,BCL7C,NUP62,ACTB,MRFAP1L1,NCOA1,SMAD1,HDAC2,SMARCD1 |
| 2.259e-05 | -10.70 | MULLIGHAN_NPM1_SIGNATURE_3_UP | MSigDB lists | MULLIGHAN_NPM1_SIGNATURE_3_UP | 313 | 75 | 17377 | 2626 |
PRKAB1,MPHOSPH8,RWDD1,UBR2,C5orf30,NIPA2,DST,CD3EAP,AP3S2,PDS5B,KIF22,ZNF770,ADCY7,CSTF1,SRPK2,RYBP,SP3,TLK1,CHMP2B,RHEB,MAN2A2,TBC1D17,IDE,FBXO28,TIMM17A,SH3GLB2,ST3GAL2,TFDP2,CLSPN,ZNF768,DNAJB2,SRGN,DCUN1D4,B4GALT4,CCDC28A,CFLAR,CEP104,TNS3,SLC31A1,EXOSC7,PPP1R8,TANK,PTPN11,FEM1B,GTSE1,OSTF1,SGCB,MTX2,NCOA2,SMC4,VOPP1,PDPK1,ABHD2,ACP2,HMGN5,CREG1,NEK7,ZMYM5,TOP3A,PIP4K2C,SEPT8,NFATC2IP,COMMD4,CAT,GNA12,KPNA4,RBM25,HNRNPH3,NEIL3,DCK,MAP3K5,TMEM14A,PDLIM5,CDK2,PURA |
| 2.279e-05 | -10.69 | GSE39820_TGFBETA1_VS_TGFBETA3_IN_IL6_TREATED_CD4_TCELL_UP | MSigDB lists | GSE39820_TGFBETA1_VS_TGFBETA3_IN_IL6_TREATED_CD4_TCELL_UP | 191 | 51 | 17377 | 2626 |
UBL3,CDS2,MAPRE1,CORO7,ARID2,ADO,SCYL1,SLC2A1,TM9SF3,CNTROB,ARF1,SLC20A1,POFUT1,CPNE3,PAIP1,ARL6IP6,HOMER1,UTP18,INTS1,CAPZA1,HADHB,CLCN6,AP2B1,NUP153,LDLRAD3,ORC3,DCTN1,CYTH1,BTAF1,TLK1,ACSL3,ATP2C1,KRAS,UBE4B,CAPZA2,BICD2,CBFB,MAP3K4,TMEM127,ATP6V1D,TTC13,ZHX1,DCK,SNAP23,ACOX1,SLC16A1,DDX5,YWHAZ,RNF139,TIGD2,ADNP2 |
| 2.279e-05 | -10.69 | GSE40277_EOS_AND_LEF1_TRANSDUCED_VS_CTRL_CD4_TCELL_DN | MSigDB lists | GSE40277_EOS_AND_LEF1_TRANSDUCED_VS_CTRL_CD4_TCELL_DN | 191 | 51 | 17377 | 2626 |
SRM,MAPRE1,PARP12,RRP15,URB2,TOR1AIP1,MRPS26,SLC29A1,LYN,STMN1,IFT27,BZW2,GFM2,MRPL19,PNO1,TFAP4,RAP1A,MED10,MCM5,SSBP3,SEPT11,POLR1B,RNF135,METTL9,C12orf75,FTSJ3,SYTL3,TRIM14,S100A6,POU2AF1,ZDHHC18,NOA1,PSPC1,NSUN2,SCFD2,SLBP,ESYT1,GAR1,MAN2A2,BOLA3,C1orf131,SGSH,PEX5,APPL2,ACAT1,XRCC3,ATF6,TMEM159,PDCD11,MRPL3,LRP8 |
| 2.279e-05 | -10.69 | GSE37301_MULTIPOTENT_PROGENITOR_VS_COMMON_LYMPHOID_PROGENITOR_DN | MSigDB lists | GSE37301_MULTIPOTENT_PROGENITOR_VS_COMMON_LYMPHOID_PROGENITOR_DN | 191 | 51 | 17377 | 2626 |
SCOC,RAF1,CDT1,DLGAP4,MRPS26,ASAH1,THRAP3,IFT27,CRLF3,EXT2,ABHD16A,CD59,USF1,TNFAIP8,NVL,PPIG,ARF5,MECR,SRI,CYC1,S100A6,TGFB1,TRAFD1,RFC3,RNASEH2C,MAP4K4,LDHA,EZR,RRM2,C9orf40,VDAC1,PEF1,FADD,CLNS1A,ECH1,ISG15,MAPK3,RPA1,HSPB11,HINT1,TAB2,PSMD8,EXOC4,RWDD4,SCARB1,CDK2,CPEB2,LONP2,ZC3HC1,DDB1,RAD51D |
| 2.279e-05 | -10.69 | GSE46606_IRF4HIGH_VS_IRF4MID_CD40L_IL2_IL5_DAY1_STIMULATED_BCELL_UP | MSigDB lists | GSE46606_IRF4HIGH_VS_IRF4MID_CD40L_IL2_IL5_DAY1_STIMULATED_BCELL_UP | 191 | 51 | 17377 | 2626 |
RMND5A,UBL3,UBN1,KLHL21,SLC41A1,GNE,MEF2A,TOP2B,CDC42SE2,XPO7,DOCK11,RGS2,ETS1,TCF19,FBXO22,IRF4,RB1,EXOSC7,TNFAIP8,TBC1D14,NUP107,PDCD2,ANAPC7,NAP1L4,UBE3B,CTDSP2,POC5,SPSB3,NIPAL3,CDKN2AIP,ERMP1,PPP1R21,TLK1,TUBGCP5,WBP1,POLG2,SERP1,MATR3,SMAP2,GINS4,PON2,DUSP3,KLHL15,AXIN1,CAPN7,HAGHL,MYO18A,NRM,WDR7,SH3GLB2,PPP5C |
| 2.280e-05 | -10.69 | NME2 (NME/NM23 nucleoside diphosphate kinase 2) | protein interactions | 4831 | 91 | 31 | 17029 | 2761 |
MOB4,RORB,WDR1,TKT,RPL38,LDHA,UBE2V1,FKBP2,OAT,MCM2,GIT2,APP,ADSS,KIF5B,FKBP1A,PPP2CA,HERC3,MDM2,HINT1,PPP1R8,ATIC,PRDX5,ACLY,AKR1B1,AHCY,TAGLN2,RUVBL2,PDIA6,TERF1,CFL1,LDHB |
| 2.280e-05 | -10.69 | LUZP4 (leucine zipper protein 4) | protein interactions | 51213 | 91 | 31 | 17029 | 2761 |
RPS15,RPL35,PPP1R18,PPP1R12A,LUZP1,THOC1,SRSF6,TLK1,RBM8A,RNPS1,CSNK2A1,BCLAF1,PAWR,THRAP3,RPL27A,RCOR3,SRRT,RPSA,SRSF1,RPA1,ERH,PDLIM1,EIF4A3,RBMX,BANF1,H2AFY,DDX5,FUS,CHTOP,SRSF10,SRPK2 |
| 2.289e-05 | -10.69 | condensed chromosome, centromeric region | cellular component | GO:0000779 | 117 | 35 | 18223 | 2701 |
ZNF207,SKA3,HJURP,CDT1,CENPF,NUF2,KIF2C,PMF1,CCNB1,SPDL1,CSNK1A1,NCAPG,MEAF6,MIS12,SPAG5,AHCTF1,KMT5C,NUP107,SS18L1,CENPM,KNTC1,NUP85,SEH1L,PLK1,RANGAP1,AURKB,SEPT7,CENPU,PHF6,CBX3,FBXO28,DSN1,BIRC5,CENPT,NDE1 |
| 2.292e-05 | -10.68 | GTTTGTT,MIR-495 | MSigDB lists | GTTTGTT,MIR-495 | 241 | 61 | 17377 | 2626 |
RORB,UBN1,TSC22D3,WDTC1,YTHDF3,KLF13,UBE2Z,UBE2Q1,NKRF,NHLRC3,RLF,ETS1,FOXO3,PAIP1,SSR1,HOMER1,PDCD10,PPP6C,CAPZA1,JOSD1,ANKRD13C,TARDBP,ST8SIA2,CAMK2G,SRSF10,YTHDC1,SRSF11,PPP3CA,RPRD1A,DCAF6,TIMP2,MLEC,PRRC2A,SNRPB,VDAC2,GMFB,ILF3,CADM1,SRSF5,SEPT7,CBFA2T2,BUD13,ZFAND5,ARMC8,EML4,PHF6,SUPT16H,VEZF1,TMEM127,TMED10,LUC7L3,MAPK6,USP32,OGT,SEL1L,VCPIP1,FKBP5,NCOA1,GLCCI1,CBX4,DYNC1LI2 |
| 2.303e-05 | -10.68 | regulation of viral process | biological process | GO:0050792 | 195 | 52 | 17256 | 2622 |
PPIB,CTDP1,CHMP2A,POLR2K,TRIM11,YTHDC2,DHX9,SMARCA4,EIF2AK4,CHD1,GTF2F1,RAD23A,TFAP4,TMEM250,CCNK,SMC3,ZNF639,BANF1,BCL2,MDFIC,TARDBP,MAVS,PABPC1,TRIM14,CFL1,SRPK2,STAU1,POLR2I,TRIM8,POLR2L,POLR2G,RAB7A,PPIE,POLR2D,ILF3,CHMP2B,TRIM28,ISG15,POLR2A,TRIM26,POLR2J,STAT1,PML,CHMP4B,DDX5,RNASEL,TRIM32,VPS4A,PARP10,DDB1,ZC3HAV1,IFI16 |
| 2.318e-05 | -10.67 | CTCAGGG,MIR-125B,MIR-125A | MSigDB lists | CTCAGGG,MIR-125B,MIR-125A | 308 | 74 | 17377 | 2626 |
IER2,ZNF76,UBN1,RPS6KA1,PLAGL2,CSNK2A1,TGOLN2,PLXNA1,MAPK14,TMEM161B,PAPOLA,PHC2,CSDE1,NUP210,BRPF3,NT5DC1,GRSF1,PPME1,ETV6,ASB6,DRAM2,ABCC5,DCTN1,SLC39A9,BAK1,ULK3,PTPN18,BAZ2A,GOPC,E2F3,LACTB,PCGF6,ATXN1,MCL1,GALNT7,ESYT1,ASB13,AP4E1,NRM,MYO18A,SOCS4,ADAM9,SCARB1,SMURF1,DDX42,NCOR2,FAM53C,KLF13,PCSK7,MXD4,GGA2,ETS1,IRF4,RNF121,MEGF8,SLC27A4,COPS7B,STAT3,LYPLA2,MAN1B1,RFXANK,MEMO1,SYVN1,RHOT2,RBM38,NEU1,MTMR3,PTPRF,CACNB1,TMEM168,OAZ2,VCPIP1,RUFY3,NIPA1 |
| 2.323e-05 | -10.67 | regulation of translation | biological process | GO:0006417 | 380 | 88 | 17256 | 2622 |
SARNP,RPS6KA1,FAM129A,PPP1R15B,EIF3D,RBM8A,DNAJC24,YTHDF3,EIF1B,RBM4,APP,PAIP1,PAIP2,PA2G4,EIF4A3,METTL14,MRPS27,EIF5,MTPN,POLR2G,NCK1,CDC123,AKT2,BTG2,RPL38,POLR2D,CIRBP,SOX4,RPS9,SERP1,EIF3H,EIF3K,GEMIN5,MKNK1,EIF4ENIF1,HNRNPR,RPS14,MAPK1,ZNF598,UNK,MIF4GD,AGO2,HABP4,DHX9,TIA1,SECISBP2,EIF2AK4,RGS2,CNOT11,METTL3,FOXO3,CNOT3,FASTKD3,MEX3C,DAPK1,LTN1,RBM3,GLE1,CNOT6L,STAT3,NSUN4,PABPC1,SAMD4B,EIF5A,CYFIP1,COA3,RHOA,ILF3,EIF2AK1,EIF2A,FXR1,CYFIP2,EIF4H,EIF4G2,DAPK3,MAPK3,CNOT9,EPRS,TSC1,UPF1,SYNCRIP,LRPPRC,KHSRP,TCOF1,CPEB2,TOB1,PURA,RNF139 |
| 2.328e-05 | -10.67 | DNA synthesis involved in DNA repair | biological process | GO:0000731 | 75 | 26 | 17256 | 2622 |
RFC3,POLK,RAD51AP1,TOP3A,RMI2,USP10,BRCA1,BLM,RFC2,RMI1,MAD2L2,NEXMIF,NPLOC4,ISG15,WRNIP1,RPA1,DTL,RPA2,RAD51C,PCNA,PALB2,POLE,RPS27A,XRCC2,XRCC3,RAD51D |
| 2.329e-05 | -10.67 | protein targeting to ER | biological process | GO:0045047 | 101 | 32 | 17256 | 2622 |
SRP72,RPL29,RPS15,SEC61B,RPL35,RPS2,RPLP2,SEC61G,RPL6,RPS10,RPL38,RPL8,RPL15,RPS24,RPL27A,RPS9,RPSA,RPL23A,RPL36,RPL11,RPL37,CHMP4A,RPL32,SEC61A1,RPL17,RPS27A,RPS14,RPLP1,RPL19,CHMP4B,SPCS3,RPS26 |
| 2.338e-05 | -10.66 | REACTOME_HIV_LIFE_CYCLE | MSigDB lists | REACTOME_HIV_LIFE_CYCLE | 106 | 33 | 17377 | 2626 |
CTDP1,NUP188,POLR2K,RAE1,NUP54,NUP205,GTF2F1,NUP210,BANF1,NUP107,NUP153,TCEA1,GTF2H2,NUP85,SEH1L,POLR2I,POLR2L,POLR2G,POLR2D,NUP155,RANGAP1,NMT2,POLR2A,XRCC5,SUPT16H,POLR2J,RPS27A,NUP62,TAF12,XRCC4,TAF6,AAAS,SSRP1 |
| 2.345e-05 | -10.66 | V$E2F_Q3 | MSigDB lists | V$E2F_Q3 | 211 | 55 | 17377 | 2626 |
POLA2,H2AFZ,ZCCHC8,RAB11B,TRMT6,SMC6,CTCF,ORC1,STMN1,FOXO3,TFRC,CNOT3,FBXO5,PCNA,SMC3,INTS7,DPYSL2,PPP1R8,PPME1,SSBP3,PDS5B,NUP153,PCYT2,ANKHD1,DNMT1,ARID4A,YTHDC1,NASP,PRKDC,ABCF2,KIF15,E2F3,SREK1,RTF1,CDC6,NFATC2IP,PKMYT1,MCM2,MAT2A,SRSF1,DDX17,HMGN2,TRIM47,ATAD2,DCK,ZNF367,NDUFA11,KBTBD7,E2F1,ATE1,RBPJ,RBBP4,SASS6,GEN1,ATXN7L2 |
| 2.346e-05 | -10.66 | GSE6259_BCELL_VS_CD4_TCELL_UP | MSigDB lists | GSE6259_BCELL_VS_CD4_TCELL_UP | 162 | 45 | 17377 | 2626 |
NCOR2,TRIM41,PNISR,UBN1,FOXM1,B4GALT5,NKRF,GTF3A,PMF1,C19orf48,SLC25A37,CD3EAP,METTL14,GTSE1,TARDBP,FAM3A,LRSAM1,NCOA2,SRPK2,TGFB1,RBM42,PRRC2A,MTA2,RAB7A,CIRBP,USP10,EMP3,LRP5,EIF3G,MFN2,DDX23,LTBP4,WNT5B,CAMKMT,PPM1G,H2AFX,USP20,AP1S1,ST3GAL2,MBD6,PPP5C,CCDC125,NRBP1,ANXA11,PTOV1 |
| 2.366e-05 | -10.65 | four-way junction DNA binding | molecular function | GO:0000400 | 16 | 10 | 17224 | 2647 |
RAD51C,XRCC2,MSH2,XRCC3,HMGB2,MEN1,BLM,YY1,MSH6,RAD51D |
| 2.373e-05 | -10.65 | Mitotic Prophase | REACTOME pathways | R-HSA-68875 | 141 | 43 | 10287 | 1696 |
NDC1,H2AFZ,NUP188,GORASP1,RAE1,NUP54,ENSA,CCNB1,NUP205,LMNA,RB1,NUP210,NEK6,KMT5A,BANF1,LPIN2,NUP107,NUP153,MCPH1,NUP85,SEH1L,SMC4,PLK1,USO1,NEK7,GORASP2,NUP155,SMC2,RAB1A,H2AFV,MAPK3,MASTL,LEMD2,PPP2CA,GOLGA2,H2AFX,NUP62,H3F3A,CCNB2,MAPK1,PPP2R2D,NUP58,AAAS |
| 2.381e-05 | -10.65 | response to radiation | biological process | GO:0009314 | 423 | 96 | 17256 | 2622 |
KARS,TXN,NPHP4,DNMT3A,NF1,TMEM109,BCL2L1,IKBIP,MAPK14,RBM4,APP,MBD4,CDK5,USF1,BABAM2,MDM2,PCNA,MTA1,XRCC2,NABP1,NOC2L,DNM2,CRY2,OGG1,SPIDR,PTPRK,PLK3,BAK1,ERCC1,DEAF1,AKT2,RAD51AP1,PBK,CIRBP,MRNIP,LRP5,AURKB,DCLRE1C,BRCA1,TANC1,MAP3K4,RAD51C,RAD18,ITGB1,H2AFX,STK11,XRCC3,CHEK2,TRIM32,FBXL3,XRCC4,RAD51D,B4GALT2,EYA1,MECP2,BABAM1,PRKAA1,RRM1,EIF2AK4,BLM,METTL3,RHBDD1,DTL,RFWD3,TIGAR,INTS7,TANK,XPA,NABP2,MSH2,BCL2,CREB1,GTF2H2,EEF1D,MSH6,TGFB1,HMGN1,POLK,NET1,PRKDC,MAP4K3,KRAS,UBE4B,MEN1,ELK1,RHOB,XRCC5,RDH11,CAT,PML,AEN,RUVBL2,YY1,HRAS,IFI16,DDB1 |
| 2.387e-05 | -10.64 | FBXO25 (F-box protein 25) | protein interactions | 26260 | 193 | 54 | 17029 | 2761 |
UBE2D3,PPP1R12A,COPA,DNAJB2,RBM8A,MYH9,EPN1,CUL1,PAWR,ATP5F1B,UBQLN2,RHBDD1,MAT2B,RPN1,PSMD2,SMC3,DNAJC8,GRK2,ATP2A2,NSRP1,PPP1R8,TMA7,TTC9C,RPN2,MSH6,CFL1,MYO5A,HP1BP3,RPAP3,RBX1,RPS10,HNRNPF,PIP4K2C,DNAJA1,ELK1,LUC7L,CCT8,FKBP3,CAND1,CXXC4,NAP1L1,ATP1A1,RPS27A,PSMD3,ODF2,LRPPRC,ACTB,RUVBL2,ATP5F1A,IGBP1,PSMC1,MYL12B,PFKP,DDX42 |
| 2.403e-05 | -10.64 | NADH dehydrogenase (ubiquinone) activity | molecular function | GO:0008137 | 39 | 17 | 17224 | 2647 |
NDUFA5,NDUFV2,NDUFS1,NDUFB6,NDUFAF2,NDUFA4,NDUFA7,NDUFB1,NDUFS7,NDUFS4,NDUFV1,NDUFA2,NDUFB4,NDUFS8,NDUFB9,NDUFS5,NDUFA3 |
| 2.403e-05 | -10.64 | NADH dehydrogenase (quinone) activity | molecular function | GO:0050136 | 39 | 17 | 17224 | 2647 |
NDUFA5,NDUFV2,NDUFS1,NDUFB6,NDUFAF2,NDUFA4,NDUFA7,NDUFB1,NDUFS7,NDUFS4,NDUFV1,NDUFA2,NDUFB4,NDUFS8,NDUFB9,NDUFS5,NDUFA3 |
| 2.411e-05 | -10.63 | IK (IK cytokine) | protein interactions | 3550 | 83 | 29 | 17029 | 2761 |
SRSF11,MND1,ZCCHC10,THOC1,XAB2,WDR18,CERK,SMU1,TOP2B,THRAP3,SRSF5,SEPT7,SAFB2,APP,SRSF1,DDX23,SUPT16H,CTNNBL1,CHD3,MFAP1,EFTUD2,ZNF326,MSH2,NUP62,SRSF3,ZNF830,NKAPD1,LUC7L2,SRSF10 |
| 2.411e-05 | -10.63 | DZIP3 (DAZ interacting zinc finger protein 3) | protein interactions | 9666 | 83 | 29 | 17029 | 2761 |
UBE2D3,CCDC93,UBE2E2,MAX,ZCCHC10,RPRD1A,BIRC3,HNRNPF,UBE2Z,RCOR1,ATXN1,UBE2V1,NUF2,UBE2I,PSMD9,BECN1,TOLLIP,GIT2,BIRC2,HMG20A,OIP5,RAD18,GRIPAP1,RABGAP1L,ARNTL,RNF38,AP1M1,CEP63,CARM1 |
| 2.411e-05 | -10.63 | FH (fumarate hydratase) | protein interactions | 2271 | 83 | 29 | 17029 | 2761 |
H2AFZ,GNPNAT1,GNPDA1,MDH2,CPOX,HEXB,TKT,TOP3A,LDHA,EZR,NANS,PKM,H2AFV,DHX15,GLOD4,NDUFV1,ATIC,NSFL1C,CAB39,AHCY,GPI,TATDN1,CDK2,ATF2,MAPK1,GPD1L,ASB6,ANXA11,LDHB |
| 2.411e-05 | -10.63 | ANKRD28 (ankyrin repeat domain 28) | protein interactions | 23243 | 83 | 29 | 17029 | 2761 |
PLK1,PPP1R9B,TRIM41,FOXK1,MAGED1,ZNF574,USP10,BRCA1,DCLRE1C,DNAJB1,NOTCH2,SEC16A,USP21,NECAP2,KRI1,MTMR3,SMC3,AGPAT2,ZNRF2,SNX18,ABRAXAS2,ODF2,PPP6C,ARHGEF2,PPP6R2,PPP6R3,MOB1A,UTP4,PPP6R1 |
| 2.412e-05 | -10.63 | MPHOSPH10 (M-phase phosphoprotein 10) | protein interactions | 10199 | 48 | 20 | 17029 | 2761 |
RPS2,NOP2,AATF,UTP15,GTPBP4,CSNK2A1,EBNA1BP2,UTP3,UTP25,KRI1,DDX56,UTP18,DGCR8,TBL3,RRS1,FBL,FTSJ3,ZC3HAV1,IFI16,DDX52 |
| 2.412e-05 | -10.63 | MRPL2 (mitochondrial ribosomal protein L2) | protein interactions | 51069 | 48 | 20 | 17029 | 2761 |
RPS15,DDX28,MRPL9,CYLD,MRPL42,PHB2,MRPL39,TUFM,CUL3,GTPBP4,MRPL16,GFM2,MASTL,MRPL50,GRSF1,MRPL40,MRPL11,MRPL13,MRPL32,FUBP1 |
| 2.412e-05 | -10.63 | SCAMP3 (secretory carrier membrane protein 3) | protein interactions | 10067 | 48 | 20 | 17029 | 2761 |
TM9SF4,TPX2,GBA,ORC1,DUSP22,STK17B,HAUS2,CDC73,BCAP31,APP,RPA1,WWP2,RPA2,SUGP1,HGS,DDOST,MBOAT1,XRCC3,CLN3,TECR |
| 2.413e-05 | -10.63 | MORF_BUB1B | MSigDB lists | MORF_BUB1B | 63 | 23 | 17377 | 2626 |
PLK1,IMMT,RFC3,PRKDC,TPX2,PLAGL2,MCM2,ABCF1,CDK11A,TARS,CDKN2C,CCNA2,IARS,GOT2,KIF14,TFDP1,KHSRP,BAZ1B,ANP32E,DNMT1,ESPL1,HDAC2,NUDC |
| 2.413e-05 | -10.63 | REACTOME_ASSEMBLY_OF_THE_PRE_REPLICATIVE_COMPLEX | MSigDB lists | REACTOME_ASSEMBLY_OF_THE_PRE_REPLICATIVE_COMPLEX | 63 | 23 | 17377 | 2626 |
PSMA8,CDT1,E2F3,PSMB7,PSMA1,CDC6,ORC1,MCM2,PSMB9,PSMD9,PSMB3,PSMC4,PSMD2,PSMA6,PSMD1,RPS27A,PSMD8,PSMD3,MCM5,E2F1,ORC3,E2F2,PSMC1 |
| 2.413e-05 | -10.63 | RHODES_CANCER_META_SIGNATURE | MSigDB lists | RHODES_CANCER_META_SIGNATURE | 63 | 23 | 17377 | 2626 |
PLK1,TSTA3,LDHA,TPX2,SMARCA4,SOX4,RBM4,TARS,NUP205,COPB2,PSMC4,SSR1,CBX3,HNRNPA2B1,MTHFD2,IARS,EIF4A3,ACLY,OGT,AHCY,KPNA2,MRPL3,TUBB |
| 2.413e-05 | -10.63 | GO_MITOCHONDRIAL_RESPIRATORY_CHAIN_COMPLEX_ASSEMBLY | MSigDB lists | GO_MITOCHONDRIAL_RESPIRATORY_CHAIN_COMPLEX_ASSEMBLY | 63 | 23 | 17377 | 2626 |
NDUFA5,NDUFV2,NDUFS1,NDUFB6,TIMMDC1,NDUFAF2,UQCR10,TMEM126B,NDUFA7,NDUFB1,TAZ,FOXRED1,NDUFS7,NDUFS4,NDUFV1,NDUFA2,NDUFB4,NDUFA11,NDUFB9,NDUFS8,NDUFS5,NDUFA3,SLC25A33 |
| 2.418e-05 | -10.63 | GSE29614_DAY3_VS_DAY7_TIV_FLU_VACCINE_PBMC_DN | MSigDB lists | GSE29614_DAY3_VS_DAY7_TIV_FLU_VACCINE_PBMC_DN | 167 | 46 | 17377 | 2626 |
PPIB,ZCCHC9,PTTG1,C5orf30,NUF2,SDF2L1,CHAC2,CCNB1,NCAPG,MYL6B,SPAG5,MAN1A1,OIP5,RNF121,SUB1,SLC38A5,SLC44A1,EFCAB11,RPN2,CENPM,OSTC,LMAN1,GINS1,POU2AF1,VOPP1,SEC61B,RNASEH2C,PBK,GNG7,MKI67,RRM2,CDC6,GALK2,EAF2,SHCBP1,MRPS14,FKBP3,TRAM2,CBWD1,UQCRH,ACADM,SNRPG,B4GALT3,GLCCI1,GEN1,CCNB2 |
| 2.418e-05 | -10.63 | PPP6R3 (protein phosphatase 6 regulatory subunit 3) | protein interactions | 55291 | 67 | 25 | 17029 | 2761 |
USP7,UNK,TNFAIP3,PRKDC,USP10,BRCA1,AP1B1,SRRT,USP21,ECH1,USP36,ANKRD28,TERF2IP,UTP25,TFAP4,EIF4A3,ZNRF2,ZNF746,PPP6C,RUVBL2,PPP6R2,MOB1A,PPP6R1,HDAC2,CDC37 |
| 2.418e-05 | -10.63 | CHERP (calcium homeostasis endoplasmic reticulum protein) | protein interactions | 10523 | 67 | 25 | 17029 | 2761 |
SART1,RPS2,CYLD,EWSR1,AGGF1,RNPS1,DHX8,JMJD6,ARGLU1,LUC7L,SF3A2,RPSA,RPA1,RBM17,RPA2,RBM23,TRIM26,HNRNPH3,U2SURP,UHRF2,XRCC3,SNRNP70,CCAR1,SRPK2,CDC5L |
| 2.422e-05 | -10.63 | EBNA1BP2 (EBNA1 binding protein 2) | protein interactions | 10969 | 121 | 38 | 17029 | 2761 |
NIFK,NOP2,SUZ12,CUL1,BRIX1,RBM4,RPL11,KRR1,LYAR,DDX56,RBM34,NOC2L,RPF2,FBL,FTSJ3,DCTN1,NOL12,DDX24,AATF,GTPBP4,CUL3,RPL8,RPL6,BRCA1,PRKRA,RPL27A,API5,MAK16,RPS9,DHX15,DOT1L,CAND1,NSA2,SYNCRIP,RRS1,ZC3HAV1,GPATCH4,IFI16 |
| 2.429e-05 | -10.63 | positive regulation of cell cycle arrest | biological process | GO:0071158 | 88 | 29 | 17256 | 2622 |
PLK3,TGFB1,BTG2,BRCA1,CCNB1,SOX4,PRKACA,CNOT11,CRLF3,CNOT3,CNOT9,PCNA,MDM2,RPS27A,CENPJ,E2F4,TFDP1,E2F1,UHRF2,PML,GTSE1,CDKN1B,CNOT6,PKD2,CHEK2,CNOT6L,TFDP2,CDK2,CARM1 |
| 2.451e-05 | -10.62 | TTK (TTK protein kinase) | protein interactions | 7272 | 79 | 28 | 17029 | 2761 |
SLC39A9,POC1A,RPS6KA1,CDCA8,AURKB,UBE4B,CNTROB,WDR5,APP,POLR2A,GLMP,GEMIN5,KIF2A,PCM1,CDC16,CDC27,CENPJ,E2F4,ODF2,MAPK6,E2F1,NAA50,CEP63,ERI3,CDK2,ESPL1,TUBB,DCTN1 |
| 2.458e-05 | -10.61 | CBS (cystathionine-beta-synthase) | protein interactions | 875 | 71 | 26 | 17029 | 2761 |
UGP2,NEK7,GOPC,ERO1A,PSMA1,AP1B1,PKM,OAT,UBE2I,NPLOC4,SEC31A,PA2G4,NUCB1,HGS,IARS,QARS,PIN1,RAD23B,UBA5,UBE3B,CDK2,LRSAM1,PDLIM5,NMD3,CBX4,IPO4 |
| 2.460e-05 | -10.61 | GO_REGULATION_OF_MRNA_SPLICING_VIA_SPLICEOSOME | MSigDB lists | GO_REGULATION_OF_MRNA_SPLICING_VIA_SPLICEOSOME | 59 | 22 | 17377 | 2626 |
YTHDC1,RBM42,SRSF6,RBM8A,RNPS1,TIA1,JMJD6,THRAP3,RBM4,HNRNPA2B1,RBM25,NSRP1,RBMX,SRSF4,TRA2B,DDX5,SRSF3,SNRNP70,SRPK2,RBM15B,PRPF19,SRSF10 |
| 2.462e-05 | -10.61 | DNA Replication | WikiPathways | WP466 | 42 | 18 | 5312 | 837 |
POLA2,MCM10,RFC3,PRIM2,CDT1,DBF4,CDC6,ORC1,MCM2,RFC2,RPA1,PRIM1,RPA2,PCNA,POLE,MCM5,ORC3,CDK2 |
| 2.467e-05 | -10.61 | TANG_SENESCENCE_TP53_TARGETS_DN | MSigDB lists | TANG_SENESCENCE_TP53_TARGETS_DN | 55 | 21 | 17377 | 2626 |
TK1,PBK,PTTG1,DBF4,TPX2,KIF23,RACGAP1,NUSAP1,EXOSC9,AURKB,NCAPG,KIF11,SPAG5,FBXO5,CCNA2,BIRC5,PRC1,NUP62,CCNB2,UBE2C,SMC4 |
| 2.518e-05 | -10.59 | PIP4K2A (phosphatidylinositol-5-phosphate 4-kinase type 2 alpha) | protein interactions | 5305 | 104 | 34 | 17029 | 2761 |
PNISR,GPBP1L1,CXXC1,RAC1,CSNK2A1,JMJD6,HDGFL2,GTF2F1,RFWD3,ZNF428,GSTK1,MEX3C,PPIG,PIN1,AFF1,AHCYL1,MTPN,BRD4,ELL2,RNPS1,PIP4K2C,RTF1,KRAS,EAF2,IWS1,DDX23,UBTF,RAD18,BRD2,CAB39,ZRANB2,STK11,TCOF1,IFI16 |
| 2.518e-05 | -10.59 | Uso1 (USO1 vesicle docking factor) | protein interactions | 56041 | 104 | 34 | 17029 | 2761 |
TMED7,GOLIM4,PPP1R12A,TM9SF4,GORASP1,CSNK1A1,SEC16A,PRKACA,SRRT,GNB2,FBRS,UBXN2A,SEC24C,GTSE1,AP2B1,YIF1B,NAP1L4,CLTB,YTHDC1,ATP2C1,ABCF2,MAN1B1,GORASP2,BCLAF1,GORAB,GOSR1,YIF1A,INF2,PDCD6,PCM1,GALNT2,SURF4,GOLGA2,TMED10 |
| 2.518e-05 | -10.59 | vacuole organization | biological process | GO:0007033 | 124 | 37 | 17256 | 2622 |
RAB14,HEXB,RAB23,ATG2B,MAP1LC3B,BECN1,TMEM165,PSEN1,ATG4A,UBXN2A,RAB35,ATG3,NSFL1C,ATG13,CORO1A,CLN6,PACS2,NAGPA,ULK3,ACP2,ATG9A,RB1CC1,PPT1,RAB7A,GBA,RAB1A,TFEB,MFN2,UBXN2B,NAGLU,ATP6V0C,WIPI2,CLN3,SMURF1,WDR45B,ABCA1,SNAPIN |
| 2.536e-05 | -10.58 | REACTOME_LATE_PHASE_OF_HIV_LIFE_CYCLE | MSigDB lists | REACTOME_LATE_PHASE_OF_HIV_LIFE_CYCLE | 93 | 30 | 17377 | 2626 |
CTDP1,POLR2I,NUP188,POLR2G,POLR2L,POLR2K,RAE1,NUP54,POLR2D,RANGAP1,NUP155,NUP205,NMT2,POLR2A,GTF2F1,SUPT16H,NUP210,POLR2J,RPS27A,NUP107,NUP62,NUP153,TCEA1,TAF12,GTF2H2,TAF6,NUP85,AAAS,SEH1L,SSRP1 |
| 2.537e-05 | -10.58 | GSE17721_POLYIC_VS_GARDIQUIMOD_8H_BMDC_DN | MSigDB lists | GSE17721_POLYIC_VS_GARDIQUIMOD_8H_BMDC_DN | 177 | 48 | 17377 | 2626 |
POLA2,BCCIP,IER2,GMFG,MRPS2,SLC41A1,WDR13,SNX15,CUL1,CHAC2,POMP,C2orf49,OAT,SRRT,RAB11A,FKBP1A,DDX56,C18orf32,INTS7,ZBTB22,LMAN1,UBE2M,CARM1,SP3,EIF3L,DDX24,SUGP2,PSMB7,TBRG4,LUC7L,GFER,SNRPA,DHX15,EIF3A,SEC31A,RAB18,KPNA1,JAK1,ORMDL2,SYNCRIP,STT3A,ZNF330,SOCS4,FAM122A,SPRYD4,CPEB2,VPS29,PDF |
| 2.543e-05 | -10.58 | CENPC (centromere protein C) | protein interactions | 1060 | 34 | 16 | 17029 | 2761 |
NIFK,SUMO2,NUF2,PMF1,MAPK14,RBM4,MIS12,CENPU,UBTF,DSN1,DGCR8,PTEN,RBM34,RPAP1,NUP153,CENPM |
| 2.543e-05 | -10.58 | LIMCH1 (LIM and calponin homology domains 1) | protein interactions | 22998 | 34 | 16 | 17029 | 2761 |
UNK,GABPA,MYH9,CAPZA2,ANLN,RFC2,CUTC,APP,RPA1,RPA2,KPNA1,HUWE1,KLHL15,MYO18A,ODF2,CDK2 |
| 2.558e-05 | -10.57 | GO_UBIQUITIN_LIGASE_COMPLEX | MSigDB lists | GO_UBIQUITIN_LIGASE_COMPLEX | 252 | 63 | 17377 | 2626 |
MIB2,CCNC,TRAF7,KLHL21,UBR2,KCTD17,BRAP,KLHL18,CBLL1,CUL1,UBE4A,DCUN1D4,ANKIB1,MAD2L2,ZER1,WWP2,PHC2,DTL,MED10,KLHL5,KLHL20,ATG3,FBXO7,CDKN1B,FBXL7,ANAPC7,RNF19A,FBXL19,DCAF6,RBX1,VHL,DCAF8,PCGF6,CUL3,FBXO9,ANAPC2,TOPORS,UBE2V1,UBE4B,BRCA1,DNAJA1,SYVN1,DCUN1D5,CDC23,CCNF,HSPA1B,CAND1,FBXO21,KEAP1,CDC16,CDC27,RAD18,KLHL15,KBTBD7,DCAF11,SEL1L,FBXL3,RNF14,UBE2C,DCAF5,CBX4,ANAPC4,DDB1 |
| 2.566e-05 | -10.57 | MORF_MBD4 | MSigDB lists | MORF_MBD4 | 80 | 27 | 17377 | 2626 |
KARS,NDUFS1,UGP2,GMFB,ENSA,CTCF,COX4I1,UBE4A,STX16,MBD4,PDCD6,NDUFA2,UTP18,SETD3,RAD23B,COX7A2L,BUD31,PPP6C,HADHB,COX5A,MDH1,YY1,PSMC1,SLC35A1,MYL12B,TMED2,EBAG9 |
| 2.566e-05 | -10.57 | REACTOME_ASPARAGINE_N_LINKED_GLYCOSYLATION | MSigDB lists | REACTOME_ASPARAGINE_N_LINKED_GLYCOSYLATION | 80 | 27 | 17377 | 2626 |
MLEC,GNPNAT1,DPM1,PRKCSH,B4GALT5,MAN1B1,MOGS,B4GALT1,MCFD2,B4GALT4,EDEM2,MAN1A1,ALG3,SEC31A,RPN1,DDOST,STT3A,DAD1,SEC24C,FUT8,RPN2,B4GALT3,ST8SIA2,LMAN1,MGAT5,B4GALT2,PREB |
| 2.584e-05 | -10.56 | GSE37416_0H_VS_12H_F_TULARENSIS_LVS_NEUTROPHIL_DN | MSigDB lists | GSE37416_0H_VS_12H_F_TULARENSIS_LVS_NEUTROPHIL_DN | 182 | 49 | 17377 | 2626 |
GNPDA1,GGA1,ALKBH5,CNTROB,SLC35B2,SNN,MAP1LC3B,RAPGEF6,RNF103,TFRC,RAB21,EIF4A3,PPME1,PHTF1,ATP13A3,PPCDC,PIK3IP1,LPCAT1,KCNAB2,CDC37,SNX8,BRD4,KLF10,TNFAIP3,GUK1,VDAC2,ARL5B,PATL1,SERP1,ABCF1,SEC31A,SGSH,ATP1A1,CHMP4A,DUSP3,MFAP1,HPS5,GADD45B,TFDP1,MAPK6,SIAH2,CHMP4B,RBPJ,RGL1,ATP6V1C1,CLN3,ZMIZ1,CDK2,HEXA |
| 2.584e-05 | -10.56 | GSE27786_BCELL_VS_ERYTHROBLAST_UP | MSigDB lists | GSE27786_BCELL_VS_ERYTHROBLAST_UP | 182 | 49 | 17377 | 2626 |
MBD1,DCAF15,PHB2,VPS45,FLOT1,KLC1,POMP,GYG1,ZADH2,MIEN1,COMMD8,C2orf68,EBP,PTPN2,LYAR,CLUAP1,NFATC3,MLX,FOXN2,LTN1,TRA2B,TAP2,CHTOP,CITED2,CNPY3,STRAP,NCOA2,CPNE1,FAM172A,NOL8,ABHD11,MEF2D,RHOT1,MCFD2,API5,KLF6,STX16,DHX57,SOCS7,PI4K2A,YIF1A,ZNF862,PDLIM1,SCAP,CHD3,CORO1C,RUVBL2,PDXK,NUDT3 |
| 2.584e-05 | -10.56 | GSE1460_INTRATHYMIC_T_PROGENITOR_VS_THYMIC_STROMAL_CELL_UP | MSigDB lists | GSE1460_INTRATHYMIC_T_PROGENITOR_VS_THYMIC_STROMAL_CELL_UP | 182 | 49 | 17377 | 2626 |
HIVEP3,USP7,LIME1,THOC1,LAGE3,CUL1,CDK13,SECISBP2,ORC1,SNN,STMN1,DTL,PA2G4,PCNA,TNFAIP8,THADA,PPP1R8,MCM5,GRSF1,PRDM4,XPA,NUP107,DAPK1,MSH2,TIMELESS,GPD1L,CCDC57,TRAPPC9,SNRNP200,CELSR2,EID1,NCK1,PGS1,TUBGCP5,ARHGDIB,MRPL16,PPWD1,DCLRE1C,POLG2,ABCF1,CHAF1A,CAT,DAP3,IDE,PCM1,PPP2R5A,QRSL1,HMGB2,RNF114 |
| 2.584e-05 | -10.56 | GSE5542_IFNG_VS_IFNA_TREATED_EPITHELIAL_CELLS_6H_UP | MSigDB lists | GSE5542_IFNG_VS_IFNA_TREATED_EPITHELIAL_CELLS_6H_UP | 182 | 49 | 17377 | 2626 |
RHOG,DNAJC2,SKA3,PKP4,MAPRE1,HJURP,C1orf112,ZFP91,POC1A,EYA1,VPS45,PMS2,ARFIP2,AGPAT3,NIPA2,GYG1,TUBGCP2,NUP205,STARD9,EXOSC7,CCP110,GOT2,FAM76B,MCPH1,STRAP,ELOF1,PLK1,PHF10,CREG1,ELL2,ASPM,AACS,MRS2,WDR18,CCDC34,DNAJC9,TOMM40,VDAC1,ARPC1A,CBFB,BBS12,PHF6,EPB41,SUPT16H,CORO1C,FAM83D,RUVBL2,SMPD4,HIPK3 |
| 2.584e-05 | -10.56 | GSE42021_CD24HI_TREG_VS_CD24HI_TCONV_THYMUS_UP | MSigDB lists | GSE42021_CD24HI_TREG_VS_CD24HI_TCONV_THYMUS_UP | 182 | 49 | 17377 | 2626 |
PPIB,PRKAB1,MCM10,ADD1,PRKCSH,XAB2,DYNLL1,UBXN1,CDK2AP2,COPE,PCSK7,MAN2B1,MXD4,PSEN1,REEP5,FOXO3,TMEM179B,RAB8A,DAD1,XRCC2,BUD31,RPL19,SLC38A10,RNASEH2A,CDC37,BAK1,CSNK1G2,STAU1,EIF3L,RBM42,AKT2,PPP1R21,NSUN2,NLN,UBE4B,EIF3G,ECH1,MAPK3,STOML2,LEMD2,EIF3K,GNAS,CRCP,CTSA,ACTB,SSNA1,HRAS,ATP6V0E1,PTOV1 |
| 2.588e-05 | -10.56 | GO_UBIQUITIN_LIKE_PROTEIN_BINDING | MSigDB lists | GO_UBIQUITIN_LIKE_PROTEIN_BINDING | 111 | 34 | 17377 | 2626 |
DNAJC2,RAE1,DNAJB2,UBXN1,BRAP,SIRT2,DCUN1D4,NPLOC4,RAD23A,USP5,UBXN2A,RAD23B,NSFL1C,CRY2,ZRANB1,RNF169,UBQLN4,TNFAIP3,DCUN1D5,TOLLIP,OPTN,IDE,KIF18A,RAD18,TAB2,UBXN2B,PML,NUP62,TRIM32,PARP10,TERF1,CBX4,FAF1,USP13 |
| 2.595e-05 | -10.56 | Lysosome | KEGG pathways | hsa04142 | 123 | 38 | 7161 | 1149 |
GGA1,MANBA,HEXB,AP3M2,ASAH1,SUMF1,MAN2B1,GGA2,AP1B1,AP3S1,GNS,ATP6V0B,CTSS,AP3S2,AP1M1,ATP6V0A2,CLTB,ATP6V0D1,GM2A,NAGPA,ACP2,GALC,PPT1,GBA,ATP6V0A1,SLC17A5,AP4E1,NEU1,CTSL,SCARB2,SGSH,NAGLU,AP1S1,ATP6V0C,CTSA,PSAP,CLN3,HEXA |
| 2.595e-05 | -10.56 | Lysosome | KEGG pathways | ko04142 | 123 | 38 | 7161 | 1149 |
GGA1,MANBA,HEXB,AP3M2,ASAH1,SUMF1,MAN2B1,GGA2,AP1B1,AP3S1,GNS,ATP6V0B,CTSS,AP3S2,AP1M1,ATP6V0A2,CLTB,ATP6V0D1,GM2A,NAGPA,ACP2,GALC,PPT1,GBA,ATP6V0A1,SLC17A5,AP4E1,NEU1,CTSL,SCARB2,SGSH,NAGLU,AP1S1,ATP6V0C,CTSA,PSAP,CLN3,HEXA |
| 2.598e-05 | -10.56 | LCA5 (LCA5, lebercilin) | protein interactions | 167691 | 117 | 37 | 17029 | 2761 |
CEP170B,MAPRE1,LUZP1,TRAF7,DYNLL1,IFT27,RCOR3,ANKRD28,CLUAP1,KIF14,TXLNA,CTPS1,GTSE1,GPATCH1,NAP1L4,IFT46,PPA1,DVL2,SRPK2,PLK1,CCDC138,CELSR2,NSUN2,CAMSAP1,MAP7D1,NUP155,ARMC8,HAUS8,NAP1L1,TIMM13,TRIM26,PCM1,HSPB11,YWHAZ,SSNA1,WDR62,YWHAH |
| 2.598e-05 | -10.56 | NUDT21 (nudix hydrolase 21) | protein interactions | 11051 | 117 | 37 | 17029 | 2761 |
SF3B1,JMJD6,SIRT2,PAPOLA,WWP2,RPA2,FLAD1,SHC1,HUWE1,SLC44A1,KIFAP3,RNF19A,LMAN1,CARM1,CDC5L,SRPK2,STAU1,EXOSC6,RNPS1,CUL3,ATXN1,EIF4H,EIF3A,MAPK3,RPA1,CAND1,GOLGA2,RPLP1,WDR76,FUS,SNRNP70,XRCC4,SMURF1,CD81,FAF1,HDAC2,PRPF4B |
| 2.599e-05 | -10.56 | rRNA processing in the nucleus and cytosol | REACTOME pathways | R-HSA-8868773 | 191 | 54 | 10287 | 1696 |
RPS15,DDX47,RPS2,NOP2,RPLP2,RPL15,RRP36,PNO1,RPL11,RPL23A,KRR1,UTP25,EXOSC7,NOL11,RPL17,UTP18,EXOSC1,RPL19,FBL,UTP4,RPL22L1,RPP25,RPL29,EXOSC6,RPL35,TEX10,WDR18,RPS10,RPL6,UTP15,RPL8,RPL38,RPS24,EXOSC9,BMS1,UTP3,RPL27A,GAR1,RPS9,RPSA,RPL36,UTP20,RPL37,RPL32,RPS27A,RPS14,TBL3,RPLP1,FAU,PDCD11,RPS26,CSNK1D,BYSL,DDX52 |
| 2.604e-05 | -10.56 | cellular response to nitrogen compound | biological process | GO:1901699 | 588 | 126 | 17256 | 2622 |
MAX,DNMT3A,AGRN,UBR2,WDTC1,RRAGC,IRF3,BCL2L1,SIRT2,ATP6V1B2,PRKACA,LYN,GNB2,APP,PRNP,EEF2K,HNRNPA2B1,CDK5,USF1,PDK2,ATP6V0B,RAB8A,CCNA2,RAP1A,MDM2,SHC1,RALB,ADCY9,PIK3R2,DNM2,AKR1B1,MAVS,AHCYL1,DNMT1,SPIDR,ADCY7,ATP6V1G1,CDC5L,LARS,KLF10,CGAS,GABPA,AKT2,GNG7,SLC26A6,ATP6V0A1,EZR,CDC6,BRCA1,PRKRA,SOCS7,IDE,SMAD2,DGCR8,GUCY1B1,STAT6,STAT1,PQBP1,ATP6V0C,ACTB,SMAD1,MAPK1,ATP6V0E1,C2CD5,HDAC2,SLC25A33,DDX58,GCLM,CASP6,AGTRAP,AGO2,PRKAA1,DHX9,FLOT1,LAMTOR3,BLM,PSEN1,AP3S1,FOXO3,METTL3,ARID1B,SRRT,TUT4,CFLAR,PTPN2,CAPN2,PDXP,GRK2,PTEN,ARHGEF2,ATP6V0A2,TIMELESS,CREB1,STAT3,GNAI2,ATP6V0D1,MYO5A,TGFB1,PDPK1,CYFIP1,PPP1R9B,PRKDC,DENND4C,PRKAR1B,RANGAP1,SRSF5,KCNQ1,ADRB2,PKM,MEN1,PDE3B,MTR,APPL1,MAPK3,EPRS,CACNB1,ATP6V1D,CSK,NSMF,ZC3H7B,LAMTOR4,PKD2,MAP3K5,ATP6V1C1,CDK2,CPEB2 |
| 2.623e-05 | -10.55 | GSE42088_2H_VS_24H_LEISHMANIA_INF_DC_UP | MSigDB lists | GSE42088_2H_VS_24H_LEISHMANIA_INF_DC_UP | 187 | 50 | 17377 | 2626 |
CAST,TSC22D3,TOR3A,TMX4,CUTA,TKT,ENSA,ASAH1,RGS2,OAT,EBP,GSTK1,CTSS,ADD3,CNN2,TECR,CNPY3,KCNAB2,PCBP2,TACC3,CARS2,AMPD2,EIF3L,TIMP2,MAPRE2,PIGT,EID1,TACC1,PPT1,SELPLG,ARHGDIB,KCNQ1,LY6E,RPS9,MTMR3,MAN2A2,PLD3,MID1IP1,QARS,EIF2D,ERGIC3,CCDC69,HMGB2,GPI,REEP4,HEXA,LTA4H,ARRB2,MZT2B,HIGD2A |
| 2.623e-05 | -10.55 | GSE37301_LYMPHOID_PRIMED_MPP_VS_GRAN_MONO_PROGENITOR_UP | MSigDB lists | GSE37301_LYMPHOID_PRIMED_MPP_VS_GRAN_MONO_PROGENITOR_UP | 187 | 50 | 17377 | 2626 |
HIVEP3,TOMM20,FAM208B,RRP15,PPP1R2,SEC61G,SRSF6,EIF3D,NUP54,PLAGL2,AGFG1,RGS2,PRPF39,BZW2,AHCTF1,CLIC4,MEX3C,GRSF1,AKAP8,TTC4,GEMIN4,FBL,CDK12,LDHB,PLK3,CCT2,MAPRE2,DDX24,BIRC3,TNFAIP3,EID1,BTG2,IDH3A,ILF3,METTL22,GAR1,ODC1,EIF3G,MAT2A,AKAP1,ALG3,MTHFD2,UAP1,ATXN2L,SIAH2,ADAM9,ATP6V0C,H3F3A,PGAM1,IPO4 |
| 2.623e-05 | -10.55 | GSE360_L_DONOVANI_VS_L_MAJOR_MAC_UP | MSigDB lists | GSE360_L_DONOVANI_VS_L_MAJOR_MAC_UP | 187 | 50 | 17377 | 2626 |
PKP4,ATXN3,KDM4A,UBR2,MDH2,EIF3D,UBXN1,TOR1AIP1,SNRPD3,CCNB1,GGA2,OAT,TTF1,NRF1,AHCTF1,UTP18,ARPC5,XRCC2,CAPZA1,MEA1,TXLNA,EI24,MSH2,RPN2,KNTC1,CREB1,MAP3K14,CNPY3,LDHB,ADCY7,PPIF,MOB4,PTPN18,RHOA,LRBA,MTMR6,EIF4G2,IRF5,MFN2,SRSF1,GLOD4,XRCC5,AKAP1,SDHB,PRDX3,LSM6,ELMO1,PGRMC1,ZNF146,SSRP1 |
| 2.623e-05 | -10.55 | GSE17721_CTRL_VS_GARDIQUIMOD_8H_BMDC_UP | MSigDB lists | GSE17721_CTRL_VS_GARDIQUIMOD_8H_BMDC_UP | 187 | 50 | 17377 | 2626 |
TRIM41,NAT9,MRPL42,MRPS15,DAP,UBXN1,GNE,GADD45G,MRPS26,NDUFA4,LANCL1,LCLAT1,MRPL19,PARK7,CCDC28A,EBP,ANKRD28,HNRNPA2B1,RAP1A,PCNA,SMC3,CCNA2,SOCS6,CDC25B,MRPL48,TECR,MRPL11,TALDO1,ZNF524,GALC,ERLIN1,NQO2,MAP4K4,HTATIP2,LRRC1,ANLN,BTBD1,HAUS8,DHX16,PRDX3,QARS,H2AFX,QRSL1,FAU,CDK2,GLCCI1,CCNB2,RPS26,SNX14,SSSCA1 |
| 2.623e-05 | -10.55 | GSE17721_ALL_VS_24H_PAM3CSK4_BMDC_UP | MSigDB lists | GSE17721_ALL_VS_24H_PAM3CSK4_BMDC_UP | 187 | 50 | 17377 | 2626 |
DNMT3A,TOR1AIP1,PCSK7,SMC6,TBC1D13,EBNA1BP2,ANKRD26,FKBP1A,CAPN2,CTSS,SUV39H2,ARPC5,UTP18,RRBP1,MRPL54,BRI3,RBM3,CLTB,PDIA6,SGCB,CFL1,LYPLA2,ATP6V1G1,NOL12,TGFB1,EIF5A,GTF3C6,TIMP2,MAPRE2,SEPT8,EMP3,NLN,CAPZA2,DDX39A,MAT2A,NECAP2,YIF1A,UTP20,SEC61A1,CCDC86,LTBP4,SNAP29,NSMCE2,MAPK6,PSAP,MYO9A,PITRM1,RPS6KC1,TRAF5,PFKP |
| 2.623e-05 | -10.55 | GSE22601_CD4_SINGLE_POSITIVE_VS_CD8_SINGLE_POSITIVE_THYMOCYTE_DN | MSigDB lists | GSE22601_CD4_SINGLE_POSITIVE_VS_CD8_SINGLE_POSITIVE_THYMOCYTE_DN | 187 | 50 | 17377 | 2626 |
BCCIP,CMAS,FEZ2,SCAMP3,SYS1,GMFG,RPS6KA1,CXXC1,SRSF6,CIB1,LAMTOR3,ENSA,SIRT2,TWF2,SEC16A,ANKIB1,C14orf119,PRKD3,C18orf32,AKAP8,ZNF260,ATP6V0A2,UPF2,MARCH2,PREB,YTHDC1,POU2AF1,SEPT9,RBX1,BAZ2A,DCAF8,ABCF2,MFNG,NARF,GMFB,EIF2AK1,ESYT1,STX16,ZDHHC3,CYB5A,SLCO4A1,PON2,TAB2,SNAP23,DCAF11,NCLN,DUSP11,YWHAZ,SNX14,SLC25A33 |
| 2.623e-05 | -10.55 | GSE43863_TH1_VS_TFH_MEMORY_CD4_TCELL_UP | MSigDB lists | GSE43863_TH1_VS_TFH_MEMORY_CD4_TCELL_UP | 187 | 50 | 17377 | 2626 |
SRM,HSPH1,TMEM184B,URB2,B4GALT5,PDAP1,SRSF6,AGFG1,NUP205,CFLAR,ERH,HOMER1,SNUPN,NUS1,IARS,KLF16,UTP18,RBM34,ZNHIT6,PPP6C,NAA50,TRA2B,FTSJ3,SLC25A1,RBM15B,PPIF,MIOS,WDR18,GTPBP4,GMFB,PSMB7,SLC25A22,ODC1,MAK16,MAT2A,PLEKHF2,USP36,AKAP1,RDH11,ALG3,EPRS,IDE,PSMD8,U2SURP,SLC16A1,RUVBL2,SCARB1,LTA4H,PFKP,CCDC137 |
| 2.623e-05 | -10.55 | GSE24634_TEFF_VS_TCONV_DAY10_IN_CULTURE_UP | MSigDB lists | GSE24634_TEFF_VS_TCONV_DAY10_IN_CULTURE_UP | 187 | 50 | 17377 | 2626 |
EWSR1,MCM10,C19orf53,FOXM1,CENPF,NUP54,KIF23,PXMP2,SLC35B1,IP6K2,ASXL2,STMN1,RBM4,CDC73,MYL6B,SPAG5,FZD6,KIFC1,DLG5,CAPN2,DTL,FANCL,IRF4,PCNA,CCNA2,SMC3,PPCDC,CTR9,KIF22,AQR,SMC4,POU2AF1,RFC3,PBK,SUGP2,ITM2A,WDHD1,CDC6,AURKB,BRCA1,SMC2,CCNF,SHCBP1,GALNT2,CHMP4A,H2AFX,KPNA2,HMGB2,ESPL1,POLQ |
| 2.639e-05 | -10.54 | autophagosome organization | biological process | GO:1905037 | 63 | 23 | 17256 | 2622 |
ULK3,ATG9A,RB1CC1,RAB7A,RAB23,GBA,ATG2B,RAB1A,MAP1LC3B,BECN1,PSEN1,ATG4A,MFN2,UBXN2A,RAB35,UBXN2B,ATG3,NSFL1C,ATG13,WIPI2,SMURF1,WDR45B,PACS2 |
| 2.654e-05 | -10.54 | GSE27786_NKTCELL_VS_MONO_MAC_DN | MSigDB lists | GSE27786_NKTCELL_VS_MONO_MAC_DN | 192 | 51 | 17377 | 2626 |
UBL3,PIGN,GMFG,POC1A,FLOT1,MAN2B1,ARF1,GGA2,CDK11B,TWF2,MOAP1,LIN9,FBXO3,KIF5B,VASP,LRRC8D,CRAT,PRC1,SS18L1,KNTC1,CABLES2,HTRA2,MORC3,VPS13B,AMPD2,CYFIP1,MLEC,KLF10,RAB7A,CKAP2L,HEBP2,RABIF,ANAPC2,BRCA1,HAUS8,TFEB,OPTN,MID1IP1,SMAD2,OAZ2,BAZ1B,C4orf46,PKD2,NDUFS5,CHEK2,CDK2,PGAM1,OAZ1,NAA60,NIPA1,GEMIN7 |
| 2.654e-05 | -10.54 | MYO6 (myosin VI) | protein interactions | 4646 | 100 | 33 | 17029 | 2761 |
DNAJC2,COX15,CYLD,REPS2,UBXN1,DCTN2,YTHDC2,MYH9,SEC16A,REPS1,COPB2,RAD23A,CALM2,CDC42,RAD23B,CAPZA1,GTSE1,AP2B1,CLTB,DCTN1,GTPBP4,WBP2,ARHGEF12,CAPZA2,ANLN,PICALM,POLR2A,OPTN,EPRS,MYO18A,USP11,CDK2,DDB1 |
| 2.659e-05 | -10.53 | GO_NEGATIVE_REGULATION_OF_CELLULAR_COMPONENT_ORGANIZATION | MSigDB lists | GO_NEGATIVE_REGULATION_OF_CELLULAR_COMPONENT_ORGANIZATION | 653 | 137 | 17377 | 2626 |
ADD1,KDM4A,XIAP,CSNK2A1,SIRT2,UBQLN2,CCNB1,PARK7,BIRC2,KIFC1,CDK5,CDC42,NEK6,NOC2L,DNM2,DNMT1,CARM1,PLK1,ERCC1,GMFB,EZR,AURKB,BRCA1,CCNF,SLC25A5,DPYSL3,MID1IP1,CHD3,MAP4,ITGB1,OGT,CHEK2,ROCK1,CLU,ARRB2,HDAC2,NUMB,SVIP,MAPRE1,GMFG,GORASP1,PHF23,DNAJB2,CENPF,CIB1,KIF23,HAUS4,RACGAP1,DNAJB1,PSEN1,HAUS2,SPAG5,LMNA,CFLAR,SMC3,CAPZA1,MSH2,LRSAM1,TERF2,IFRD1,MYBL2,CAPZA2,CBFA2T2,KDM3A,XRCC5,HAUS8,GOLGA2,CSK,ARAP1,RUFY3,ZNF207,WASF2,ANKRD27,CHMP2A,FEZ2,RAF1,PTTG1,RAC1,TPX2,MYH9,BCL2L1,STMN1,TWF2,TERF2IP,KIF14,PARL,CEP63,CORO1A,STRAP,TMBIM1,PPIF,UBQLN4,BIRC3,GOPC,TUBGCP5,VDAC2,PPP2CA,KIF2A,PEX5,CHMP4A,PPP2R5A,CORO1C,STAT1,CHMP4B,TUBB,CSNK1D,KIF3B,TRIP12,MECP2,DCTN2,TUBGCP2,RAB11A,MAD2L2,FBXO5,STARD9,PTEN,ARHGEF1,PRC1,H2AFY,ARHGEF2,SPTAN1,TGFB1,PPP3CA,RHOA,ASPM,NEK7,KIF11,PICALM,HSPA1B,ATAD2,BIRC5,PML,WDR62,YWHAH,TERF1,ESPL1,SNAPIN |
| 2.668e-05 | -10.53 | positive regulation of cellular process | biological process | GO:0048522 | 5055 | 856 | 17256 | 2622 |
FGFR1OP,TSC2,ADD1,MAP3K7CL,HEXB,AGPAT1,XIAP,GLUD1,CCNL2,PPP1R16B,MIEN1,EDRF1,RBM4,FBXO22,EEF2K,CDK5,CALM2,USF1,PSMD1,NEK6,DNM2,FNIP2,ECD,SENP1,MLST8,USP34,BAK1,PLK3,ERCC1,NRAS,AATF,GABPA,MCL1,TOPORS,DCUN1D5,ARF4,STOML2,BRMS1,MID1IP1,SMAD2,RAD18,RPS27A,LIMK1,AXIN1,MYO18A,OGT,MLYCD,ATP6V0C,RNASEL,TFDP2,SMAD1,E2F2,PDCD4,SLC25A33,HIVEP3,CLSPN,PHF23,RHOC,TRIO,DHX9,KCTD17,EZH1,EIF2AK4,PSMD9,APH1B,PARN,CDC73,LMNA,MCTS1,DDRGK1,TFAP4,DDX56,PDXP,RIMS3,MEGF8,FBXO7,FOXN2,MYDGF,PABPC1,NUP85,PHKG2,NSUN4,CYFIP1,AGGF1,FOXK1,MAPKAPK3,RB1CC1,MTA2,TSPAN31,MYBL2,BCLAF1,SRSF5,CBFA2T2,ELK1,RHOB,SCARB2,FNTA,ETS2,DUSP3,CSK,SETD3,CNOT6,CFAP20,RUFY3,RNF139,ALS2,EGLN1,RHOG,ANKRD27,KARS,TRERF1,NQO1,IVNS1ABP,POC1A,CHD1L,ACTR3,ANK3,TPX2,MYH9,CREBL2,SLC35B2,DAZAP2,PRKACA,STMN1,STAM,CPNE3,ANKIB1,APP,RAB21,SP100,MTA1,GMEB1,RNF19A,MAVS,ATF2,RBM15,CLN6,ZC3H3,RPRD1B,PDCL3,DCTN1,ADCY7,CPNE1,ULK3,SHOC2,PSRC1,KAT7,MAP4K4,WBP2,POLR2D,RNPS1,CIRBP,E2F3,PFKFB3,CDCA2,NUSAP1,GORAB,DNAJA1,MEF2D,RAB1A,TAZ,DDX17,TAF2,PPP2CA,CORO1C,NSMCE2,HIPK2,RPLP1,CBLN2,TICAM1,PPP5C,GEN1,LRP8,USP13,RPS2,SRSF6,ZFP91,HABP4,FLOT1,TRAK1,ABHD14B,ATP5F1B,IP6K2,WDR5,HDGFL2,ETS1,SAPCD2,RPA2,ERH,PSMD2,PDCD10,HUWE1,PRDM4,ARHGEF1,GTSE1,GTF2H2,TPCN1,S100A6,PDPK1,STAU1,PPP3CA,TNFAIP3,JTB,LDHA,HEBP2,LLPH,ZP3,PICALM,CIP2A,RPA1,KEAP1,GPS2,WNT5B,PITX1,MAPK6,CAPN7,PML,HMGB2,PSAP,CD81,USF2,YWHAH,FAF1,AGRN,THOC1,AAMDC,GPBP1L1,PPP1R15B,FAM129A,CSNK2A1,NENF,S1PR2,BIRC2,TRIM65,FANCI,SSR1,CREM,PRNP,TET3,ABL2,DLG5,PCNA,GLIS2,IL6ST,ZNF639,ETV6,PIK3R2,XRCC2,ZFYVE27,MYBL1,MTPN,CCAR1,RYBP,CDC37,PLK1,SP3,EXOSC6,SEPT9,MIOS,RBX1,APH1A,MRPL12,EZR,CDC6,UBE2V1,LRP5,IL12RB1,EAF2,BRCA1,ANLN,PRKRA,ODC1,USP21,RHEB,OPTN,DPYSL3,AGPAT2,E2F4,SOCS4,ADAM9,PIEZO1,DVL1,BEND6,SINHCAF,POT1,C2CD5,NUMB,ZNF564,PHB2,NKD2,LAMTOR3,CTCF,CHCHD2,RACGAP1,CDK13,NCKAP1,PPP3CB,DOCK11,RLF,ASXL2,CNOT11,CRLF3,ARID1B,SUB1,RB1,TNS3,VASP,MLX,NUS1,CCP110,TIGAR,MBD2,SSBP3,XPA,ZNF746,CTR9,TIMELESS,MDFIC,RBM3,ICE2,MAML1,LRSAM1,AACS,ACSL3,LDB1,UTP15,KRAS,MAP4K3,RTF1,NFATC2IP,ARPC1A,EIF4G2,IRF5,PSMC4,RXRB,GOLGA4,LAMTOR4,NLRC5,TBPL1,RUVBL2,ATP5F1A,BTBD10,RNF114,USP7,SART1,CYLD,TRAF7,FOXM1,DYNLL1,SUMO2,RRAGC,LYN,DUSP22,PCBP1,BCAP31,RAD23A,VAV1,NRF1,PSMA6,MDM2,TNFAIP8,PIN1,PDCD2,TARDBP,CORO1A,LMAN1,SPIDR,DVL2,PRPF19,PPIF,TIMP2,BIRC3,POLR2G,PPT1,PSMA8,RAB7A,BTG2,NFATC2,USP36,SRSF1,IDE,SCAP,RBL1,PSMD3,TIMM17A,PLGRKT,UHRF2,XRCC3,NCOA1,H3F3A,SMAD4,PARD3,BCL2L12,SLC30A9,SMAP1,DAP,CDT1,AGO2,SMC6,HMGN3,NKRF,CSNK1A1,PAGR1,SCYL2,TFRC,PTPN2,IRF4,HOMER1,SS18L1,PTGES3,RHOA,HMGN5,PRKDC,ARHGEF12,PDCD6,NEK1,BIRC5,TWSG1,TFE3,CDCA7L,E2F1,PKD2,RBPJ,NR2F2,UBE2C,IFI16,TXN,ZNF496,H2AFZ,PDCD6IP,ADAM10,CXXC1,YTHDF3,PLXNA1,CCNB1,UBE2I,SLC20A1,PARK7,GLMP,PA2G4,NOL11,FIZ1,AP2B1,TRA2B,CDC25B,TFG,DNMT1,SEH1L,CDC5L,KLF10,AKT2,MRNIP,DDX20,AURKB,USP22,SLC25A5,CBFB,RFC2,RAB2B,DOT1L,MAP3K4,HHEX,WAS,PSMD8,ITGB1,ARRB2,SLF1,TRAF5,ZMAT3,NMD3,HDAC2,SVIP,DDX58,HSPH1,MAPRE1,SCOC,DHPS,CHTF18,HLA-E,VAV2,PRKAA1,GADD45G,KIF23,B4GALT1,CYCS,NOTCH2,PSEN1,METTL3,CNOT3,JMY,SPAG5,WDR48,CFLAR,NDUFS4,FKBP1A,TMEM250,ARPC5,HDAC7,MSH2,DAPK1,GNAI2,EEF1D,SOCS5,EIF5A,WDR1,PIP4K2C,MFNG,KCTD20,EXOSC9,ARID1A,ADRB2,CYFIP2,FXR1,PTTG1IP,KDM3A,MAP2K2,SF3A2,CCT8,PSMB3,FAS,XRCC5,DERL1,CAT,SERTAD2,HSPBP1,GOLGA2,NSF,RBMX,ACLY,ARAP1,CEBPG,PPP3R1,FAM83D,PIAS2,GPI,YY1,MAP3K5,RNF14,CDK2,ZC3HAV1,CDKN2A,DNMT3A,ATXN3,RWDD1,RPS6KA1,RAF1,SUZ12,EIF3D,GPR89A,RAC1,MAGED1,BCL2L1,EPM2A,CD320,TERF2IP,MOAP1,CRKL,CCNA2,SHC1,SIAH1,RALB,LPIN2,ADCY9,MRPS27,CDKN1B,TP53BP2,CDK12,CFL1,ANKLE2,CCT2,CDKN2AIP,BRD4,RFC3,CDC123,TAOK1,CUL3,EDF1,PSMB9,TRIM28,SERP1,SUPT16H,VEZF1,RAD51C,PPP2R5A,HINT1,SAFB,H2AFX,STAT1,ATF6,TRIM32,BEND3,EYA2,ATMIN,CSNK1D,POU3F2,PKP4,MECP2,TCF3,BABAM1,CBLL1,BLM,RAB11A,FOXO3,MAD2L2,WWP2,GTF2F1,CCNK,PTEN,ELP5,CENPJ,PTPN11,PRC1,AXIN2,CARF,CITED2,CNOT6L,MAP3K14,CREB1,UBE2M,MSH6,NCOA2,KAT2A,LONRF3,NEK7,NET1,ILF3,RFXANK,TBRG4,ANAPC2,KCNQ1,KLF6,MACF1,MARK2,FADD,SH3GLB1,POLR2A,HGS,PRDX3,STX18,TFDP1,KHSRP,DDX5,ESPL1,PURA,DDB1,RORB,MIB2,ZBED3,CCNC,ZNF76,IER2,NPHP4,UBE2E2,PLXNC1,NOP2,HNRNPAB,NF1,KMT2E,UBE2Z,PTP4A3,SIRT2,UBQLN2,MAPK14,BECN1,ZNF804A,RAP1A,C18orf32,CDC42,EIF4A3,METTL14,SRI,AKR1B1,TCEA1,SLC35C2,CARMIL1,ARID4A,CARM1,ELOF1,SRPK2,COPS8,DEAF1,LARS,TRIM8,NCK1,VHL,SOX4,STK17B,ABHD5,PAF1,UBTF,CAB39,ZNF268,STK11,CHEK2,CLU,VPS4A,ROCK1,PSMC1,CAPN1,UBE2D3,NSMCE4A,PPP1R12A,GORASP1,CIB1,TIA1,MEF2A,THRAP3,RGS2,SRRT,RHBDD1,APOPT1,LYAR,DTL,NFATC3,MED10,FAM89B,ZNF335,BUD31,TENM3,BCL2,YBX1,ZRANB1,ATP5IF1,ERLIN1,GBA,PSMA1,EIF2A,SEPT7,CCDC71L,DAPK3,ISG15,CAND1,GNAS,TSC1,NAP1L1,NSMF,CDCA5,NUP62,YWHAZ,DNPH1,ZFP90,EHD4,SNRNP70,TOB1,N4BP2L2,SMARCD1,ADNP2,WASF2,TCF12,CHMP2A,ASH1L,IFI27L1,CHERP,SMARCA4,PLAGL2,IRF3,TWF2,PAIP1,MIEF1,USP5,HNRNPA2B1,RRN3,ANKLE1,BABAM2,NVL,KIF14,AKAP8,CHTOP,F2R,ABI1,HTRA2,MOSPD1,CHP1,POU2AF1,CGAS,PGGT1B,PSMB7,WIPF1,CADM1,EDEM2,PEF1,TOLLIP,RPS9,SURF4,TAB2,HNRNPR,STAT6,GADD45B,WDR59,ARNTL,CANT1,SCARB1,TMEM101,AKNA,SMURF1,MAPK1,TSPAN5,TMEM33,PDF,NAT14,MIF,DNAJC2,KIF3B,GOLPH3L,SH2D3A,EYA1,DBF4,KLF13,PAWR,DCUN1D4,PIP4K2A,FBXO5,FERMT3,KIF5B,FASTKD3,FGFR3,GRK2,CTNNBL1,PELO,TANK,NABP2,ZDHHC13,H2AFY,BRD7,ARHGEF2,ATG13,STAT3,TGFB1,ELOVL5,TELO2,COA3,DCAF6,ADAM17,HMGN1,FAM49B,ASPM,MIER1,ATP2C1,PRKAR1B,PRMT2,MEN1,SYMPK,MAPK3,MFN2,TFEB,HSPA1B,CNOT9,UPF1,ATAD2,PLAA,OSBPL8,KMT2B,ZMIZ1,HRAS,SLF2,TERF1 |
| 2.685e-05 | -10.53 | GSTK1 (glutathione S-transferase kappa 1) | protein interactions | 373156 | 52 | 21 | 17029 | 2761 |
PPIF,PDCD6IP,DCAF8,DNAAF5,CYCS,PIP4K2A,MATR3,FANCI,GSTK1,RPN1,PEX5,DDOST,IARS,EFTUD2,LRPPRC,RPN2,PPP2R2D,IPO4,HNRNPM,DCTN1,PRPF19 |
| 2.686e-05 | -10.52 | HELICc | smart domains | SM00490 | 107 | 32 | 9493 | 1367 |
DDX58,RECQL,DDX47,SHPRH,YTHDC2,CHD1L,DHX9,SMARCA4,DHX8,BLM,CHD1,DDX56,EIF4A3,DDX31,DDX28,SNRNP200,DDX24,DHX29,BTAF1,DDX20,DDX39A,DHX57,DHX15,DDX17,DDX23,RAD54B,DHX16,CHD3,DDX5,DDX42,POLQ,DDX52 |
| 2.695e-05 | -10.52 | YAMAZAKI_TCEB3_TARGETS_DN | MSigDB lists | YAMAZAKI_TCEB3_TARGETS_DN | 202 | 53 | 17377 | 2626 |
MIF,SEPHS2,GCLM,CMAS,ST13,AGTRAP,GNPDA1,MANBA,SLC2A1,DBF4,EBNA1BP2,SLC20A1,STMN1,PARK7,TFRC,PNO1,STRBP,AHSA1,ARL6IP1,AKR1B1,YBX1,RBM3,TCEA1,TALDO1,DNMT1,S100A6,MSH6,LDHB,SAP30,CDC5L,FDFT1,PSRC1,NASP,EMB,MYBL2,ITM2A,NUSAP1,VDAC1,FXR1,KIF11,FKBP3,XRCC5,STOML2,GOLGA4,SEPT1,LTBP4,UBXN2B,CDCA7L,ACLY,KPNA2,RUVBL2,TUBB,ADAM23 |
| 2.704e-05 | -10.52 | GO_POSITIVE_REGULATION_OF_ORGANELLE_ORGANIZATION | MSigDB lists | GO_POSITIVE_REGULATION_OF_ORGANELLE_ORGANIZATION | 536 | 116 | 17377 | 2626 |
ZBED3,PDCD6IP,ZDHHC8,DYNLL1,RAC1,ACTR3,STARD7,PLAGL2,SIRT2,CCNB1,BECN1,PARK7,MOAP1,CDK5,RALB,SIVA1,AKAP8,CDKN1B,CYB5R1,TP53BP2,CHTOP,LMAN1,DNMT1,HTRA2,MLST8,BAK1,PLK1,PPIF,CCT2,ERCC1,PSRC1,SEPT9,NCK1,AKT2,PSMB7,CUL3,TUBGCP5,WBP2,WIPF1,LRP5,NUSAP1,AURKB,BRCA1,RAB1A,TRIM28,USP36,STOML2,PAF1,MAP3K4,WAS,SURF4,PSMD8,LIMK1,NSMCE2,OGT,VPS4A,MAPK1,POT1,SMAD4,UBE2D3,PHB2,GORASP1,KCTD17,NCKAP1,RGS2,TUBGCP2,PIP4K2A,APOPT1,JMY,FBXO5,RB1,PDXP,VASP,PTEN,HUWE1,ARPC5,BRD7,CTR9,H2AFY,BCL2,ATG13,CNOT6L,LRSAM1,NSUN4,TERF2,TGFB1,CYFIP1,RHOA,KAT2A,NEK7,WDR1,MIER1,PIP4K2C,RTF1,ADRB2,SEPT7,ARPC1A,CCT8,SH3GLB1,MAPK3,GOLGA2,BIRC5,CDCA5,STX18,TFDP1,PPP3R1,PML,E2F1,YWHAZ,CNOT6,RUVBL2,UBE2C,YWHAH,ESPL1,HRAS,TERF1 |
| 2.723e-05 | -10.51 | lytic vacuole | cellular component | GO:0000323 | 677 | 139 | 18223 | 2701 |
ADA2,RAB14,TSC2,AGRN,ABCC10,HEXB,NHLRC3,GYG1,CMTM6,GLMP,NAPG,PA2G4,PSMD1,AP1M1,AKR1B1,AP2B1,MARCH2,DRAM2,SEH1L,WDR41,LARS,MIOS,ARHGAP45,LRBA,SLC17A5,RHEB,AHNAK,WDR11,NAGLU,ATP6V0C,VPS4A,CLN3,CAPN1,ANXA11,STARD3NL,DNAJC5,CCZ1,CDIP1,LAMTOR3,SDC2,ASAH1,B4GALT1,MAN2B1,PSEN1,TMEM165,WDR48,TMEM179B,GNS,ZNRF2,ATP6V0A2,TMEM8A,LPCAT1,ATP6V0D1,FTL,CPQ,CREG1,GBA,ADRB2,CCT8,RMC1,PI4K2A,CAT,SCARB2,NSF,SNAP23,LAMTOR4,ACLY,CTSA,HEXA,SNX14,ANKRD27,TRIP10,ANK3,TMEM97,RRAGC,ATP6V1B2,AP1B1,LYN,GNB2,CPNE3,USP5,CLCN6,BRI3,TMEM9,TMBIM1,GM2A,ATP6V1G1,CPNE1,CCT2,PPT1,RAB7A,GOPC,ATP6V0A1,CHMP2B,TOLLIP,PON2,DSN1,DDOST,SURF4,WDR59,AP1S1,SCARB1,MAPK1,AP2S1,CHID1,DYNC1LI2,TUBB,ANXA6,MANBA,SRGN,FLOT1,SPPL2A,CAPN2,CTSS,TPCN1,MYO5A,MFSD12,ACP2,TNFAIP3,GALC,SNX2,HEBP2,RFFL,WDR81,KCNQ1,SPPL2B,NEU1,CTSL,SGSH,ATP6V1D,HGS,MAGT1,CCZ1B,SNAP29,CTBS,IMPDH1,PSAP,ATP6V1C1,SNAPIN |
| 2.723e-05 | -10.51 | lysosome | cellular component | GO:0005764 | 677 | 139 | 18223 | 2701 |
ADA2,RAB14,TSC2,AGRN,ABCC10,HEXB,NHLRC3,GYG1,CMTM6,GLMP,NAPG,PA2G4,PSMD1,AP1M1,AKR1B1,AP2B1,MARCH2,DRAM2,SEH1L,WDR41,LARS,MIOS,ARHGAP45,LRBA,SLC17A5,RHEB,AHNAK,WDR11,NAGLU,ATP6V0C,VPS4A,CLN3,CAPN1,ANXA11,STARD3NL,DNAJC5,CCZ1,CDIP1,LAMTOR3,SDC2,ASAH1,B4GALT1,MAN2B1,PSEN1,TMEM165,WDR48,TMEM179B,GNS,ZNRF2,ATP6V0A2,TMEM8A,LPCAT1,ATP6V0D1,FTL,CPQ,CREG1,GBA,ADRB2,CCT8,RMC1,PI4K2A,CAT,SCARB2,NSF,SNAP23,LAMTOR4,ACLY,CTSA,HEXA,SNX14,ANKRD27,TRIP10,ANK3,TMEM97,RRAGC,ATP6V1B2,AP1B1,LYN,GNB2,CPNE3,USP5,CLCN6,BRI3,TMEM9,TMBIM1,GM2A,ATP6V1G1,CPNE1,CCT2,PPT1,RAB7A,GOPC,ATP6V0A1,CHMP2B,TOLLIP,PON2,DSN1,DDOST,SURF4,WDR59,AP1S1,SCARB1,MAPK1,AP2S1,CHID1,DYNC1LI2,TUBB,ANXA6,MANBA,SRGN,FLOT1,SPPL2A,CAPN2,CTSS,TPCN1,MYO5A,MFSD12,ACP2,TNFAIP3,GALC,SNX2,HEBP2,RFFL,WDR81,KCNQ1,SPPL2B,NEU1,CTSL,SGSH,ATP6V1D,HGS,MAGT1,CCZ1B,SNAP29,CTBS,IMPDH1,PSAP,ATP6V1C1,SNAPIN |
| 2.753e-05 | -10.50 | GO_VESICLE_TARGETING | MSigDB lists | GO_VESICLE_TARGETING | 76 | 26 | 17377 | 2626 |
USO1,TRAPPC9,GORASP1,CUL3,MCFD2,RAB1A,SEC16A,PSEN1,ANKRD28,CD59,SEC31A,SEC23IP,GOLGA2,NSF,TMED10,SNAP29,SEC24C,SNAP23,PPP6C,PPP6R3,TFG,LMAN1,PPP6R1,CSNK1D,TMED2,PREB |
| 2.781e-05 | -10.49 | GAVIN_FOXP3_TARGETS_CLUSTER_P6 | MSigDB lists | GAVIN_FOXP3_TARGETS_CLUSTER_P6 | 89 | 29 | 17377 | 2626 |
PLK1,TK1,MCM10,CLSPN,ASPM,PBK,CENPF,TPX2,CDCA3,CDCA8,RRM2,DCTD,NUSAP1,NUF2,KIF2C,AURKB,IL12RB1,CCNB1,NCAPG,ODC1,SPAG5,MYO1F,CCNA2,BIRC5,RPL17,CEP55,CDCA5,ATF6,CCNB2 |
| 2.786e-05 | -10.49 | FKBP8 (FK506 binding protein 8) | protein interactions | 23770 | 96 | 32 | 17029 | 2761 |
PPP3CA,VHL,PSMB7,CUL3,TMEM216,PSMA1,BCL2L1,ADRB2,MAPK14,PSMB3,RHEB,PSMC4,SSR1,EVC2,PSMD2,PSMD1,HSPBP1,PSMA6,BABAM2,PSMD3,PGRMC1,XRCC3,BCL2,PTGES3,CLN3,MRPL11,PSMC1,TERF1,ABCC1,MLST8,PTPRK,EGLN1 |
| 2.807e-05 | -10.48 | PPP2R1A (protein phosphatase 2 scaffold subunit Aalpha) | protein interactions | 5518 | 275 | 71 | 17029 | 2761 |
IER2,FGFR1OP,DYNLL1,RAF1,SDHA,PARK7,RAP1A,SYNM,PPME1,INTS1,NABP1,CLCN6,INTS12,RPN2,ABI1,FGFR1OP2,CDC5L,ANKLE2,IDH3A,RAB7A,CUL3,NFATC2,PPFIA3,MCM2,RPSA,PPP2CA,SMAD2,CDCA4,ATP1A1,PPP2R5A,CHEK2,PTPDC1,BTF3,PPP5C,ARRB2,SMURF1,PPP2R2D,INTS2,ZCCHC8,NACA,DNAAF5,STRN4,SIKE1,FOXO3,RAB11A,WWP2,RPN1,PDCD10,PPP4R1,DAPK1,TNPO3,ARHGEF2,CYC1,MOB4,STRIP1,MARK2,PRDX1,CIP2A,BBS12,DERL1,GNA12,RAB18,C1orf131,CCDC6,RBMX,KLHL15,MAPK6,FAM122A,ACADM,ATP6V1C1,ESPL1 |
| 2.832e-05 | -10.47 | Golgi-associated vesicle | cellular component | GO:0005798 | 171 | 46 | 18223 | 2701 |
TMED7,RAB14,COPA,ADAM10,HLA-E,SCYL1,GPR89A,COPE,VTI1A,CHIC2,TGOLN2,TMED3,SEC16A,SYNRG,APP,COPG2,COPB2,HLA-A,SPPL2A,CD59,RAB8A,SAR1A,SEC24C,ZDHHC13,YIF1B,LMAN1,CLTB,TMED2,KDELR1,USO1,GOPC,PACS1,MCFD2,PEF1,SPPL2B,YIF1A,SEC31A,HLA-B,NUCB1,SEC23IP,PDCD6,GOLGA2,TMED10,SCAP,AP1S1,ECPAS |
| 2.832e-05 | -10.47 | nucleoside monophosphate biosynthetic process | biological process | GO:0009124 | 120 | 36 | 17256 | 2622 |
GALK1,COX5B,UCK2,UCK1,ATP5F1B,ADPGK,ATP5PF,HDDC2,GART,DUT,ATIC,UPRT,ATP6V0A2,CYC1,TGFB1,AMPD2,TK1,LDHA,ATP6V0A1,ADSL,DCTD,OGDH,ATP5MF,PKM,STOML2,ADSS,ATP5MC3,DCK,PRPS2,DHTKD1,IMPDH1,ATP5F1A,GPI,PGAM1,NIPSNAP2,PFKP |
| 2.834e-05 | -10.47 | SIRT6 (sirtuin 6) | protein interactions | 51548 | 171 | 49 | 17029 | 2761 |
USP7,FAM208B,NSMCE4A,TM9SF4,TSC22D3,KIAA0232,USP48,METTL3,LMNA,MDM2,SMC3,EFTUD2,TXLNA,CAPZA1,MSH2,H2AFY,CDKN1B,ANAPC7,SENP1,MSH6,SMC4,SNRNP200,CELSR2,MTA2,PRKDC,EHMT1,ABCF2,WDHD1,USP10,SMC2,CCT8,TRIM28,MATR3,MAPK3,XRCC5,SYNCRIP,CDC27,CHD3,ACLY,FTSJ1,CBWD1,RUVBL2,TCOF1,RBBP4,PDLIM5,N4BP2L2,FAF1,DDB1,HDAC2 |
| 2.849e-05 | -10.47 | GSE15271_CXCR4_POS_VS_NEG_GC_BCELL_UP | MSigDB lists | GSE15271_CXCR4_POS_VS_NEG_GC_BCELL_UP | 168 | 46 | 17377 | 2626 |
MIF4GD,GOLPH3L,NDUFAF2,SUMO2,OLA1,ARFIP2,TCF19,ATPAF1,PABPC4,NDUFS7,NUDT19,UBXN2A,PDXP,UBE2Q2,RAD23B,MECR,CYB5R1,POLR1B,DNMT1,MTX2,AMPD2,TELO2,TDP1,EIF3L,PRIM2,SNRPB,ILF3,LDHA,RNPS1,DCTD,THNSL1,SMC2,DDX39A,PSMB3,ASF1B,RAD54B,ALG3,TMEM41A,MTHFD2,PRDX3,DGCR8,TOMM6,KHSRP,PPP1R11,PDXK,IDH3B |
| 2.895e-05 | -10.45 | TGAGATT,MIR-216 | MSigDB lists | TGAGATT,MIR-216 | 107 | 33 | 17377 | 2626 |
MAPRE1,PARP12,UBN1,GPBP1L1,ZFP91,YTHDF3,KLF13,AKT1S1,RAB6A,AP3S1,RAB11A,TMEM161B,CCDC28A,PTEN,BRI3,TNPO2,YBX1,RP2,HNRNPM,SMC4,PPP1R9B,KRAS,CADM1,CAPZA2,MEF2D,ARID1A,KDM3A,MATR3,EML4,OSBPL11,CSK,VCPIP1,NCOA1 |
| 2.901e-05 | -10.45 | phosphatase binding | molecular function | GO:0019902 | 156 | 44 | 17224 | 2647 |
TSC2,PPP1R12A,STRN4,ENSA,PPP3CB,MAPK14,GTF2F1,TERF2IP,RPA2,MTMR4,PPME1,PIK3R2,PPP1R12C,CDKN1B,BCL2,ANAPC7,CRY2,MAST2,MVP,STAT3,PPP6R1,ANKLE2,PPP1R9B,SHOC2,PPP1R18,NFATC2,KCNQ1,MASTL,MAPK3,CHCHD3,MTMR3,SMAD2,JAK1,CDC27,CSK,STAT6,PPP3R1,PPP1R11,PPP6R3,MAP3K5,IGBP1,MAPK1,ANAPC4,PARD3 |
| 2.902e-05 | -10.45 | kinase binding | molecular function | GO:0019900 | 688 | 145 | 17224 | 2647 |
FGFR1OP,ADAM10,PRKCSH,CCNB1,MAPK14,BECN1,PARK7,CDKN2C,CALM2,USF1,PCNA,NEK6,CDC42,FIZ1,PIK3R2,PPP1R12C,CDC25B,CDC37,PTPRK,PLK1,RHOBTB3,NCK1,EZR,CDC6,AURKB,RHEB,WAS,AXIN1,CAB39,ADAM9,ACTB,CHEK2,DVL1,SMAD1,ARRB2,SLC12A7,MAPRE1,PPP1R12A,RHOC,MEF2A,TOP2B,CDK13,RACGAP1,PARN,LRRC14,RB1,KIF13B,HDAC7,FBXO7,MSH2,PIK3IP1,MAML1,MVP,SLC12A2,SOCS5,MAPKAPK3,RB1CC1,ACSL3,APPL1,RHOB,FAS,FNTA,GOLGA2,NSF,CSK,DUSP3,QARS,FAM83D,YWHAZ,MAP3K5,PDLIM5,TOB1,CDKN2A,RHOG,CYLD,FOXM1,RAF1,RAC1,TPX2,BCL2L1,AP1B1,DAZAP2,GLRX3,TWF2,PRKACA,CPNE3,RAD23A,CCNA2,SP100,SHC1,KIF14,TBC1D14,PPME1,PIN1,CDKN1B,MAVS,ATF2,CDK12,DVL2,DCTN1,CHP1,VDAC1,TOLLIP,ATP1A1,PPP2R5A,HINT1,STK38,TICAM1,ZC3HC1,TCF3,DCTN2,DBF4,SIKE1,FOXO3,MAD2L2,FBXO5,JAKMIP1,PTPN2,CCNK,FGFR3,PDCD10,PTEN,CENPJ,PRC1,PTPN11,H2AFY,ATG13,STAT3,PDPK1,TELO2,RHOA,TNFAIP3,STRIP1,PRKAR1B,JTB,RFFL,KCNQ1,BORA,KIF11,PDE3B,CNOT9,PRDX3,MAPK6,PGAM1,FAF1 |
| 2.904e-05 | -10.45 | HIST2H2AB (histone cluster 2 H2A family member b) | protein interactions | 317772 | 56 | 22 | 17029 | 2761 |
NIFK,ZNF512,SUZ12,MCM2,PEF1,MAK16,RBM4,APP,LMNA,ZNF428,RPA2,NAP1L1,DGCR8,RBM34,MCM5,KBTBD7,H2AFX,PARL,ARRB2,ZC3H3,GPATCH4,SSRP1 |
| 2.904e-05 | -10.45 | RBM7 (RNA binding motif protein 7) | protein interactions | 10179 | 56 | 22 | 17029 | 2761 |
EXOSC6,CHERP,ZCCHC8,SF3B1,CUL3,HNRNPF,DHX8,EXOSC9,LUC7L,RBM4,SRRT,HMG20A,SF3B2,PCNA,EXOSC7,RBMX,EXOSC1,SRSF3,CDK2,YWHAH,PPP2R2D,CDC5L |
| 2.904e-05 | -10.45 | TMX1 (thioredoxin related transmembrane protein 1) | protein interactions | 81542 | 56 | 22 | 17029 | 2761 |
EWSR1,TXN,VDAC2,CYSTM1,TMEM216,GMCL1,ESYT1,ADRB2,SNN,VDAC1,DUSP22,LYN,CD320,SSR1,EVC2,FAS,TMEM179B,RDH11,UPF1,H2AFX,LMAN1,ATF2 |
| 2.910e-05 | -10.44 | RPL35A (ribosomal protein L35a) | protein interactions | 6165 | 92 | 31 | 17029 | 2761 |
RPS15,COX15,RPS2,RPL35,CYLD,RPLP2,HNRNPUL2,RPS10,RPL6,RPL8,CUL3,RNPS1,RPL15,CUL1,RTF1,MCM2,RPL27A,RPS9,RPSA,RPL11,RPL36,RPL23A,CAND1,RPL37,RPL32,RPL17,RPS14,RBM34,RPL19,RRS1,ARRB2 |
| 2.932e-05 | -10.44 | GO_HISTONE_METHYLATION | MSigDB lists | GO_HISTONE_METHYLATION | 72 | 25 | 17377 | 2626 |
ASH1L,SUZ12,MECP2,CXXC1,EHMT1,WDR82,RTF1,EZH1,MEN1,PRMT2,WDR5,KDM3A,DOT1L,TET3,SUV39H2,SETD3,PRDM4,ZNF335,OGT,PRMT7,CTR9,BEND3,FBL,ARID4A,CARM1 |
| 2.966e-05 | -10.43 | Organelle biogenesis and maintenance | REACTOME pathways | R-HSA-1852241 | 340 | 85 | 10287 | 1696 |
EXOC3,FGFR1OP,PRKAB1,NPHP4,MRPS15,DYNLL1,MRPL39,MAPK14,PRKACA,MRPL19,MRPL50,CLUAP1,NRF1,RAB8A,MRPL34,MRPS27,RP2,CEP63,ATF2,MRPL32,CARM1,MRPL57,DCTN1,PLK1,CCT2,GABPA,MRPL12,MRPL43,TMEM216,MEF2D,POLG2,MRPS14,ARF4,MRPL2,DAP3,HSPB11,MRPL55,CHCHD1,MRPL27,NCOA1,MRPL13,CSNK1D,TUBB,KIF3B,MRPL9,MAPRE1,MRPL42,MTERF1,MRPS2,TWNK,DCTN2,MRPS26,HAUS4,CYCS,ATP5F1B,IFT27,RAB11A,HAUS2,GFM2,CCP110,CENPJ,MRPL54,KIFAP3,MRPL48,MRPL40,MRPL11,CREB1,MRPL21,IFT46,NCOA2,TCTEX1D2,TUFM,MRPS10,MRPL16,RAB3IP,CCT8,BBS12,HAUS8,PCM1,ODF2,EXOC4,SSNA1,PKD2,NDE1,MRPL3 |
| 2.972e-05 | -10.42 | GSE40666_UNTREATED_VS_IFNA_STIM_CD8_TCELL_90MIN_DN | MSigDB lists | GSE40666_UNTREATED_VS_IFNA_STIM_CD8_TCELL_90MIN_DN | 178 | 48 | 17377 | 2626 |
SRM,C9orf78,TP53RK,UGP2,SRSF6,TOR1AIP1,CUTA,DNAJB1,BRIX1,NDUFA2,CCP110,SNX18,BANF1,EFTUD2,UBA5,AP1M1,TALDO1,PLCL2,CNPY3,N4BP2,ATP6V0D1,PHKG2,RHBDD2,CAMK2G,S100A6,IMPA2,TACC3,RLIM,TMEM160,CLCN3,POLR2L,HMGN5,DPM1,MAPKAPK3,WDR1,EHMT1,ELP4,EIF2A,PRMT2,TRAM2,ZNF367,EIF2D,UQCRH,MBOAT1,RRS1,TFDP2,RPS26,MRPL3 |
| 2.972e-05 | -10.42 | GSE29618_PRE_VS_DAY7_POST_TIV_FLU_VACCINE_BCELL_DN | MSigDB lists | GSE29618_PRE_VS_DAY7_POST_TIV_FLU_VACCINE_BCELL_DN | 178 | 48 | 17377 | 2626 |
MIF,MBD1,ZNF207,TMBIM4,ANXA6,MRPS2,GGA1,UQCR10,PTTG1,ARFIP2,IRF3,GYG1,ZNF267,CCNB1,RLF,MAPK14,GGPS1,TTF1,FBXO22,KLHL5,UCHL5,FOXN2,RPN2,MAST2,ATF2,MICAL3,CSNK1G3,CFL1,TACC3,KDELR1,RYBP,TXNL1,NET1,DCAF8,RPL6,HEBP2,LRRC1,PITPNB,CYFIP2,TXNL4A,PPP2CA,DNAJC10,TRAM2,PFDN4,SRSF3,RRS1,FAM208A,NUDT3 |
| 2.972e-05 | -10.42 | GSE18791_CTRL_VS_NEWCASTLE_VIRUS_DC_6H_UP | MSigDB lists | GSE18791_CTRL_VS_NEWCASTLE_VIRUS_DC_6H_UP | 178 | 48 | 17377 | 2626 |
NDUFA5,GXYLT1,NOP2,MRPS2,URB2,GSPT2,SLC25A12,NIT2,PDCD7,BRIX1,TWF2,WRB,HMG20A,FLAD1,NAPG,ZNF302,SUV39H2,CD3EAP,DNAAF2,MSH2,PRADC1,TNRC18,ASB6,DDX28,NXT1,TMEM115,FAM172A,MBLAC2,MRPL12,RFXANK,FRAT2,MTMR12,TMEM147,THNSL1,HHEX,FBXO21,ZNF317,TMEM168,NIP7,PDRG1,WNT5B,KBTBD7,FAM126A,TRIM32,RRS1,OSGEPL1,BYSL,GEMIN7 |
| 2.972e-05 | -10.42 | GSE1791_CTRL_VS_NEUROMEDINU_IN_T_CELL_LINE_12H_UP | MSigDB lists | GSE1791_CTRL_VS_NEUROMEDINU_IN_T_CELL_LINE_12H_UP | 178 | 48 | 17377 | 2626 |
ST13,KIAA0100,MCCC1,TKT,CERK,XPO7,CUTC,REEP5,BZW2,PIP4K2A,LMNA,WRNIP1,EEF2K,ZER1,CDK5,FAM192A,IRF4,SNRNP25,GLIS2,DNAAF2,ETV6,RAB4A,TTC9C,HADHB,FAM89B,AKR1B1,MRPL48,AQR,TTLL12,ATP6V0D1,TMEM14C,UBE2M,NUP85,LUC7L2,EMB,DENND4C,PRKDC,SLC26A6,PACS1,TMEM147,MEN1,HAGH,ECH1,PCM1,VPS26B,ARNTL,GPI,WIPI2 |
| 2.984e-05 | -10.42 | Small_GTP-bd_dom | interpro domains | IPR005225 | 160 | 44 | 18492 | 2768 |
RHOG,RAB14,RAB11B,RHOC,RAC1,RAB23,ARF1,RAB6A,EFL1,IFT27,GFM2,RAB11A,GTPBP3,RAB8A,RAB21,RAP1A,CDC42,SAR1A,RALB,RAB35,ARF5,RAB4A,EFTUD2,ARL5A,NRAS,RHOA,RAB7A,GTPBP4,KRAS,RIT1,RHOT1,RAB1A,GUF1,RAB5B,ARL5B,RAB22A,ARF4,RHOB,RHEB,RAB2B,RAB18,RAB24,HRAS,RHEBL1 |
| 3.011e-05 | -10.41 | CPNE3 (copine 3) | protein interactions | 8895 | 31 | 15 | 17029 | 2761 |
TERF2IP,PA2G4,GCLM,STAU1,VASP,QARS,ZNF746,USP42,ANXA5,GPI,SND1,MCM2,SDHA,POT1,TERF1 |
| 3.018e-05 | -10.41 | GSE17721_4H_VS_24H_POLYIC_BMDC_UP | MSigDB lists | GSE17721_4H_VS_24H_POLYIC_BMDC_UP | 183 | 49 | 17377 | 2626 |
COPA,DEPDC1,UQCR10,RACGAP1,GLUD1,ABCB10,SND1,MFSD10,HDDC2,FKBP1A,LYAR,GSTK1,UBXN2A,SLC38A5,IARS,TIMM23,CAPZA1,ATP6V0A2,YBX1,RBM3,MRPL11,TFG,MINPP1,PDIA6,LPCAT1,EEF1D,SEH1L,DVL2,PSRC1,TIMP2,FOXK1,BIRC3,NSUN2,RPS10,NUSAP1,BRCA1,RPL36,SERTAD2,BIRC5,SNAP29,NDUFA11,CEP55,EXOC4,ACLY,PRMT7,TRAF5,TSPAN5,HIPK3,ADAM23 |
| 3.018e-05 | -10.41 | GSE25088_WT_VS_STAT6_KO_MACROPHAGE_IL4_STIM_UP | MSigDB lists | GSE25088_WT_VS_STAT6_KO_MACROPHAGE_IL4_STIM_UP | 183 | 49 | 17377 | 2626 |
SLC12A7,KIF3B,FAM53C,ABCC10,B4GALT1,EZH1,EPHX2,HAUS2,KRI1,KDM2A,GSDMB,HDAC7,INTS1,ARHGEF1,ZNF335,CNPY4,GTSE1,CYB5R1,PIK3IP1,RNF19A,OGG1,SPSB3,PTPRK,VOPP1,UBQLN4,TAOK1,SLC26A6,NFATC2IP,AMDHD2,DCLRE1C,TAZ,RHOT2,POLG2,HAGH,DAPK3,RBM38,RXRB,ANKZF1,CSNK1G1,ARNTL,PTPN7,AEN,NCOA1,KLHDC4,PPP6R2,REEP4,CHMP7,BRD9,PARD3 |
| 3.021e-05 | -10.41 | NKAPD1 (NKAP domain containing 1) | protein interactions | 55216 | 88 | 30 | 17029 | 2761 |
YTHDC1,FYTTD1,C9orf78,CDC40,XAB2,MECP2,PPIE,CRNKL1,CUL3,RNPS1,DHX8,CSNK2A1,JMJD6,THRAP3,SF3A2,SRSF1,UBTF,SNRNP25,ZNF317,EIF4A3,CLK3,PPIG,BUD31,GPATCH1,TRA2B,AQR,ZC3H3,NSUN4,SRSF10,PRPF4B |
| 3.023e-05 | -10.41 | Hematopoietic Stem Cell Gene Regulation by GABP alpha/beta Complex | WikiPathways | WP3657 | 22 | 12 | 5312 | 837 |
DNMT3A,PTEN,GABPA,ETV6,SMARCA4,BCL2,MCL1,BCL2L1,SMAD4,DNMT1,FOXO3,TERF2 |
| 3.027e-05 | -10.41 | ABL1 (ABL proto-oncogene 1, non-receptor tyrosine kinase) | protein interactions | 25 | 218 | 59 | 17029 | 2761 |
USP7,WASF2,FGFR1OP,EWSR1,BCL2L1,REPS1,APP,GTF2F1,WRNIP1,VAV1,CRKL,ABL2,CDK5,SUB1,RB1,MDM2,PCNA,SHC1,HUWE1,SH3BP1,PIK3R2,CDKN1B,AP2B1,PTGES3,CABLES2,MAVS,CREB1,LRRC59,ABI1,HNRNPM,DVL2,SPTAN1,SRPK2,RYBP,YTHDC1,ARHGAP17,LARS,PTPN18,NCK1,PRKDC,ILF3,BRCA1,EIF2A,POLR2A,PRDX1,RPL37,CAT,HSPA4,JAK1,PFDN4,HIPK2,RPLP1,DDX5,YWHAZ,FUS,YWHAH,TERF1,CABLES1,DDB1 |
| 3.040e-05 | -10.40 | GO_POSITIVE_REGULATION_OF_TRANSFERASE_ACTIVITY | MSigDB lists | GO_POSITIVE_REGULATION_OF_TRANSFERASE_ACTIVITY | 593 | 126 | 17377 | 2626 |
CCNC,TXN,TRAF7,RAF1,MAGED1,RAC1,TPX2,CUL1,CCNL2,S1PR2,CCNB1,UBE2I,PRKACA,MAPK14,LYN,PARK7,CRKL,CDK5,CALM2,RAP1A,PSMD1,PSMA6,SHC1,CDC42,NVL,RALB,PIN1,KIF14,ADCY9,CDKN1B,ANAPC7,CDC25B,F2R,ABI1,DVL2,ADCY7,PLK1,BAK1,COPS8,CCT2,PSRC1,RFC3,PSMA8,PSMB7,TOPORS,CDC6,AURKB,DCUN1D5,CDC23,RAB1A,RFC2,PSMB9,MAP3K4,PPP2CA,CDC16,TAB2,RPS27A,PSMD8,AXIN1,PSMD3,GADD45B,RPLP1,CAB39,ADAM9,STK11,CLU,MAPK1,PSMC1,LRP8,POT1,MIF,HSPH1,RPS2,CLSPN,GORASP1,CHTF18,ZFP91,VAV2,PRKAA1,GADD45G,CIB1,DCUN1D4,PSEN1,PSMD9,FBXO5,CCNK,FGFR3,PSMD2,PDCD10,PTEN,PTPN11,MDFIC,MAP3K14,GNAI2,PDPK1,TGFB1,TELO2,ADAM17,RHOA,MAPKAPK3,NEK7,PRKAR1B,JTB,PSMA1,ANAPC2,KRAS,MAP4K3,ADRB2,ZP3,MAP2K2,MARK2,PSMB3,MAPK3,PSMC4,MASTL,CDC27,GOLGA2,CSK,OSBPL8,PKD2,MAP3K5,UBE2C,CD81,HRAS,ANAPC4,ALS2 |
| 3.056e-05 | -10.40 | GSE5589_UNSTIM_VS_45MIN_LPS_STIM_MACROPHAGE_DN | MSigDB lists | GSE5589_UNSTIM_VS_45MIN_LPS_STIM_MACROPHAGE_DN | 188 | 50 | 17377 | 2626 |
NCOR2,CORO7,GMFG,KIAA0100,TSC2,POLR2K,XAB2,PTTG1,DCTN2,PDXDC1,APOPT1,RPL11,HNRNPA2B1,SLC27A4,UPF2,PCYT2,C8orf59,AQR,ERI3,CITED2,TALDO1,RNF5,PRRC2A,C16orf72,DCAF8,RDH10,ANAPC2,NDUFA7,WBP1,EDF1,COMMD4,FOXRED1,HAGH,RPL36,MAN2A2,HINT1,STT3A,EIF2D,OAZ2,HAGHL,DCAF11,MEGF9,SCARB1,ARHGAP23,RTN3,AP2S1,SLC25A39,PDCD4,USP13,TMEM131 |
| 3.056e-05 | -10.40 | GSE17721_PAM3CSK4_VS_GADIQUIMOD_6H_BMDC_UP | MSigDB lists | GSE17721_PAM3CSK4_VS_GADIQUIMOD_6H_BMDC_UP | 188 | 50 | 17377 | 2626 |
IER2,NOP2,IVNS1ABP,SHPRH,FAM76A,DHX9,B4GALT1,XPO7,BRIX1,METTL3,SAC3D1,PAIP2,NAPG,SLC1A4,MED10,ZNF639,SLC44A1,PELO,PPCDC,SPTSSA,DVL2,NUDC,FDFT1,FTL,RPRD1A,EID1,RDH10,TAOK1,MRPL12,CAMSAP1,NARF,MKI67,CDC6,GALK2,SMC2,USP36,RPA1,UPF1,EIF4ENIF1,PTER,TBL3,DBI,H2AFX,FAM126A,CTSA,YY1,NGLY1,ZNF598,VPS29,PDF |
| 3.056e-05 | -10.40 | GSE9988_ANTI_TREM1_VS_ANTI_TREM1_AND_LPS_MONOCYTE_UP | MSigDB lists | GSE9988_ANTI_TREM1_VS_ANTI_TREM1_AND_LPS_MONOCYTE_UP | 188 | 50 | 17377 | 2626 |
UBE2D3,CYTIP,TMEM203,KDM4A,PHF23,DYNLL1,SUMO2,KIAA0232,ARID5A,KLF13,UBQLN2,GGA2,TWF2,PCBP1,GNB2,BCAP31,MBD4,PHC2,NUS1,MED8,SP100,KLHL20,ARF5,FBXO7,ZCCHC2,ARL6IP1,AP1M1,FEM1B,PPIF,MAPKAPK3,AMD1,FRAT2,USP10,WDR82,MAP7D1,USP22,OGFR,TSR2,PI4K2A,SH3BP5,SCARB2,ACTB,CENPBD1,YY1,ARRB2,PURA,NRBP1,CSNK1D,SNAPIN,ZNF511 |
| 3.056e-05 | -10.40 | GSE9960_HEALTHY_VS_GRAM_NEG_SEPSIS_PBMC_UP | MSigDB lists | GSE9960_HEALTHY_VS_GRAM_NEG_SEPSIS_PBMC_UP | 188 | 50 | 17377 | 2626 |
SLC30A9,COMMD10,ZNF496,GMFG,TCF3,TMX4,CUTA,MRPS26,GLUD1,SLC29A1,NOTCH2,AP3S1,LCLAT1,PDXDC1,HMG20A,RPN1,NFATC3,FBXO7,RAB4A,HADHB,ANP32A,NDUFB9,CLN6,SLC35A1,ATP6V0D1,TPCN1,RNLS,PTPN18,TIMP2,SNX2,TIMMDC1,ATP6V0A1,ARHGDIB,TMEM147,ESYT1,MPG,H2AFV,RHOB,GNAS,PFDN5,TPD52L2,ALDH3B1,HHEX,RWDD4,IARS2,MBOAT1,TRIM52,CLN3,HEXA,TMEM33 |
| 3.056e-05 | -10.40 | GSE13411_NAIVE_VS_SWITCHED_MEMORY_BCELL_DN | MSigDB lists | GSE13411_NAIVE_VS_SWITCHED_MEMORY_BCELL_DN | 188 | 50 | 17377 | 2626 |
TMEM106C,MDH2,HEXB,NIT2,FAM136A,PIP4K2A,HMG20A,PABPC4,HLA-A,EDC3,IARS,MEA1,PPP6C,CAPZA1,PABPC1,PACS2,TERF2,ABCC1,MLST8,POU2AF1,VOPP1,DENND4C,NUDT4,SUGP2,MRPL12,NARF,TUFM,EIF2AK1,VKORC1,NDUFB1,HAGH,EIF3G,FAS,TMEM127,TPD52L2,QARS,GOLGA8A,EIF2D,PPM1G,ITGB1,RBMS1,ZDHHC7,ATP6V0C,ZNF268,GALNT10,RTN3,ZMAT3,PURA,DDX52,USP13 |
| 3.060e-05 | -10.39 | Ras protein signal transduction | biological process | GO:0007265 | 247 | 62 | 17256 | 2622 |
RHOG,WASF2,RAB14,NF1,RAB11B,RHOC,RAC1,RAB23,BRAP,MYO9B,RAB6A,NCKAP1,MAPK14,IFT27,RAB11A,RAPGEF6,PARK7,RTKN,CRKL,RAB21,RB1,RAB8A,CCNA2,RAP1A,SHC1,CDC42,RALB,RAB35,RAB4A,ARHGEF1,DNMT1,CFL1,CYFIP1,SHOC2,RHOBTB3,RHOA,NRAS,MAPKAPK3,RAB7A,RFXANK,ARHGEF12,KRAS,RIT1,RHOT1,RAB1A,RHOT2,RAB5B,TRIM28,RAB22A,RHOB,RAB2B,GNA12,RAB18,WAS,ELMO1,RAB24,LIMK1,ROCK1,CDK2,HRAS,ALS2,CDKN2A |
| 3.062e-05 | -10.39 | PML body | cellular component | GO:0016605 | 100 | 31 | 18223 | 2701 |
USP7,SP3,MAX,TRIM8,UBN1,SUMO2,TOP3A,SMC6,TOPORS,UBE2I,BLM,PATL1,RPAIN,PARK7,DAPK3,RPA1,RFWD3,RPA2,RB1,EIF4ENIF1,SP100,KLHL20,PTEN,HIPK2,NSMCE2,ARNTL,PML,PIAS2,CHEK2,HIPK3,MORC3 |
| 3.067e-05 | -10.39 | UQCRB (ubiquinol-cytochrome c reductase binding protein) | protein interactions | 7381 | 60 | 23 | 17029 | 2761 |
RPS2,NDUFS1,UQCR10,RPS10,RPL6,NDUFA4,COX4I1,VDAC1,SDHA,NDUFS4,RPL11,SDHB,NDUFV1,DDOST,MYO18A,NDUFA11,COX7A2L,COX5A,ACAT1,UQCRH,ACTB,CYC1,APOOL |
| 3.067e-05 | -10.39 | DTL (denticleless E3 ubiquitin protein ligase homolog) | protein interactions | 51514 | 60 | 23 | 17029 | 2761 |
COPS8,UBE2E2,KAT2A,RBX1,SHPRH,CDT1,AURKB,WDR5,UBE2I,LYN,MDM2,PCNA,RAD18,KMT5A,DDA1,MSH2,YWHAZ,COPS6,YWHAH,TOB1,SSSCA1,DDB1,MSH6 |
| 3.067e-05 | -10.39 | POLR1B (RNA polymerase I subunit B) | protein interactions | 84172 | 60 | 23 | 17029 | 2761 |
ZNF207,EIF3L,LZTR1,POLR2I,POLR2L,AKT2,LDB1,DHX8,GIT2,TWISTNB,RPL11,RPA1,CAND1,RPL37,RPA2,RRN3,CD3EAP,TBL3,ACTB,POLR1B,TCOF1,USP11,ARRB2 |
| 3.070e-05 | -10.39 | NME1-NME2 (NME1-NME2 readthrough) | protein interactions | 654364 | 45 | 19 | 17029 | 2761 |
PPIF,WDR1,TKT,LDHA,UBE2V1,FKBP2,OAT,MCM2,FKBP1A,ADSS,HINT1,PIN1,PRDX5,AKR1B1,AHCY,TAGLN2,TALDO1,CFL1,LDHB |
| 3.077e-05 | -10.39 | GSE6269_HEALTHY_VS_FLU_INF_PBMC_UP | MSigDB lists | GSE6269_HEALTHY_VS_FLU_INF_PBMC_UP | 154 | 43 | 17377 | 2626 |
KCTD7,RAE1,MUM1,EIF3D,CERK,KLC1,HMGN3,COX4I1,EZH1,SND1,UBE2I,C2orf68,RPL17,HUWE1,FBL,MGAT5,DDX28,EIF3L,ELOVL5,RPL29,PHF10,POLR2G,PBXIP1,DCAF8,BTAF1,SUGP2,RPS10,SRSF5,SEPT7,LUC7L,NDRG3,EIF3H,EIF3K,DAP3,CDC16,DGCR8,QARS,CSNK1G1,EIF2D,NCLN,BTF3,PDCD11,PTDSS1 |
| 3.085e-05 | -10.39 | GSE17186_BLOOD_VS_CORD_BLOOD_CD21HIGH_TRANSITIONAL_BCELL_UP | MSigDB lists | GSE17186_BLOOD_VS_CORD_BLOOD_CD21HIGH_TRANSITIONAL_BCELL_UP | 193 | 51 | 17377 | 2626 |
TOR3A,C5orf30,RRAGC,KIF23,SUMF1,NIPA2,TMED3,PMF1,NOTCH2,B4GALT4,OAT,PSEN1,RAB11A,GNB2,FANCL,CCNA2,DUT,KIFAP3,TMEM8A,MOB1A,RNF135,LPCAT1,ZNRD1,TMBIM1,IMPA2,SOCS5,WDR41,NAGPA,TGFB1,LAP3,EID1,SIGMAR1,TSPAN31,CAPZA2,NUTF2,AKAP1,ATAD2,PALB2,HINT1,DSN1,WDR11,STT3A,HIPK2,NRM,MYO18A,DBI,E2F1,ANP32E,SLC25A39,ATP6V0E1,ALS2 |
| 3.085e-05 | -10.39 | GSE39152_SPLEEN_CD103_NEG_VS_BRAIN_CD103_POS_MEMORY_CD8_TCELL_UP | MSigDB lists | GSE39152_SPLEEN_CD103_NEG_VS_BRAIN_CD103_POS_MEMORY_CD8_TCELL_UP | 193 | 51 | 17377 | 2626 |
KIF3B,KARS,GPR132,SCAMP3,EYA1,PHRF1,ALKBH5,ENSA,ARFIP2,AP1B1,UBE2I,TWF2,PARN,APP,WDR48,FERMT3,USP5,SLC25A36,VAV1,PTPN11,ARHGEF2,RNF26,TIPARP,UBE2M,PHKG2,ASB6,LDHB,NUDC,CSTF1,RHOA,CIC,ABCF2,ATXN1,WBP1,IL12RB1,DAPK3,MAPK3,CAND1,SH3BP5,PLD3,GALNT2,SEC61A1,FAM110A,PSMD3,ACOX1,PRPS2,ST3GAL2,FAU,MZT2B,ABCA1,CSNK1D |
| 3.085e-05 | -10.39 | GO_UBIQUITIN_LIKE_PROTEIN_LIGASE_ACTIVITY | MSigDB lists | GO_UBIQUITIN_LIKE_PROTEIN_LIGASE_ACTIVITY | 193 | 51 | 17377 | 2626 |
MIB2,CCNC,UBR2,TRIM11,XIAP,BRAP,CBLL1,CUL1,UBE2Z,ZNRF3,UBE4A,UBE2I,ANKIB1,WWP2,FANCL,RNF121,MDM2,MED10,CDC42,SIAH1,ZNRF2,PPIL2,LTN1,RNF19A,LRSAM1,UBE2M,RNF5,RLIM,PRPF19,RBX1,VHL,RNF25,CUL3,RFFL,ANAPC2,TOPORS,KIAA1586,UBE2V1,UBE4B,SYVN1,RAD18,SIAH2,PIAS2,UHRF2,RNF38,TRIM32,RNF14,UBE2C,SMURF1,RNF139,RNF114 |
| 3.105e-05 | -10.38 | GNF2_BUB1 | MSigDB lists | GNF2_BUB1 | 26 | 13 | 17377 | 2626 |
PLK1,FOXM1,ASPM,CDT1,CDCA8,RRM2,KIF2C,AURKB,SMC2,CCNB2,ESPL1,SPAG5,ASF1B |
| 3.106e-05 | -10.38 | E2F mediated regulation of DNA replication | REACTOME pathways | R-HSA-113510 | 34 | 16 | 10287 | 1696 |
POLA2,PRIM2,CDT1,RRM2,CDC6,ORC1,CCNB1,PRIM1,FBXO5,PPP2CA,RB1,PCNA,TFDP1,E2F1,ORC3,TFDP2 |
| 3.113e-05 | -10.38 | Antigen processing: Ubiquitination & Proteasome degradation | REACTOME pathways | R-HSA-983168 | 311 | 79 | 10287 | 1696 |
MIB2,KCTD7,TRIM41,UBE2E2,TRAF7,UBR2,TRIM11,CUL1,UBE2Z,UBE2Q1,FBXO22,PSMD1,PSMA6,SIAH1,UBA5,FBXW2,ANAPC7,RNF19A,ASB6,RLIM,PSMA8,RBX1,VHL,RNF25,CUL3,PSMB7,UBE2V1,CDC23,ASB13,CCNF,PSMB9,BTBD1,TRIM4,CDC16,RPS27A,PSMD8,TPP2,PSMD3,TRIM32,KLHL42,FBXL3,SMURF1,PSMC1,UBE2D3,TRIP12,KLHL21,UBE4A,PSMD9,HERC3,PSMD2,UBE2Q2,MEX3C,KLHL20,KLHL5,HUWE1,ZNRF2,FBXO7,LTN1,FBXL7,UBE3B,UBE3C,LRSAM1,FBXL19,UBE2M,PSMA1,FBXO9,ANAPC2,PSMB3,PSMC4,FBXO21,FBXO41,KEAP1,CDC27,KBTBD7,SIAH2,RNF14,UBE2C,ANAPC4,RNF114 |
| 3.117e-05 | -10.38 | NUDC (nuclear distribution C, dynein complex regulator) | protein interactions | 10726 | 84 | 29 | 17029 | 2761 |
PLK1,KARS,NPHP4,UGP2,POC1A,CAST,MDH2,NFATC2,BRCA1,DNAJA1,DNAJB1,EML4,TARS,EVC2,PAPOLA,HUWE1,CCDC6,PPME1,CORO1C,ADAM9,FKBP5,WIPI2,PPP6R2,H3F3A,IGBP1,POT1,NUP85,VPS29,CDC5L |
| 3.134e-05 | -10.37 | GO_NUCLEAR_ENVELOPE_DISASSEMBLY | MSigDB lists | GO_NUCLEAR_ENVELOPE_DISASSEMBLY | 44 | 18 | 17377 | 2626 |
PLK1,NUP188,RAE1,NUP54,NUP155,CCNB1,NUP205,LMNA,NUP210,NEK6,BANF1,NUP107,NUP62,NUP153,CCNB2,NUP85,SEH1L,AAAS |
| 3.134e-05 | -10.37 | GO_MEMBRANE_DISASSEMBLY | MSigDB lists | GO_MEMBRANE_DISASSEMBLY | 44 | 18 | 17377 | 2626 |
PLK1,NUP188,RAE1,NUP54,NUP155,CCNB1,NUP205,LMNA,NUP210,NEK6,BANF1,NUP107,NUP62,NUP153,CCNB2,NUP85,SEH1L,AAAS |
| 3.134e-05 | -10.37 | MODULE_363 | MSigDB lists | MODULE_363 | 44 | 18 | 17377 | 2626 |
TXNL1,NDUFV2,POLR2I,RPL15,ATP6V1B2,NDUFS4,ATP6V0B,NDUFV1,CRAT,PGRMC1,YBX1,NDUFS8,ATP6V0C,RBPJ,BTF3,NDUFS5,PPA1,ATP6V1G1 |
| 3.137e-05 | -10.37 | ubiquitin ligase complex | cellular component | GO:0000151 | 311 | 73 | 18223 | 2701 |
MIB2,TRAF7,MPHOSPH8,DCAF15,UBR2,KLHL18,CUL1,ANKIB1,ZER1,PHC2,BABAM2,ATG3,DDA1,CDKN1B,ANAPC7,RNF19A,SPSB3,RBX1,VHL,PCGF6,CUL3,TOPORS,UBE2V1,DNAJA1,BRCA1,DCUN1D5,CCNF,CDC23,PEF1,BTBD1,CDC16,RAD18,SEL1L,KLHL42,FBXL3,DCAF5,CBX4,KLHL21,KCTD17,BRAP,CBLL1,GMCL1,UBE4A,DCUN1D4,MAD2L2,WWP2,DTL,KLHL20,MED10,KLHL5,FBXO7,FBXL7,FBXL19,DCAF6,DCAF8,FBXO9,ANAPC2,UBE4B,SYVN1,CAND1,HSPA1B,FBXO21,PDCD6,KEAP1,CDC27,KLHL15,KBTBD7,DCAF11,UBE2C,RNF14,ANAPC4,DDB1,ZSWIM6 |
| 3.149e-05 | -10.37 | Macroautophagy | REACTOME pathways | R-HSA-1632852 | 67 | 25 | 10287 | 1696 |
CHMP2A,PRKAB1,TSC2,ATG9A,RB1CC1,DYNLL1,PRKAA1,LAMTOR3,RRAGC,CHMP2B,MAP1LC3B,BECN1,RHEB,ATG4A,MTMR3,TSC1,CHMP4A,ATG3,LAMTOR4,ATG13,CHMP4B,WIPI2,CHMP7,WDR45B,MLST8 |
| 3.150e-05 | -10.37 | EIF3E (eukaryotic translation initiation factor 3 subunit E) | protein interactions | 3646 | 105 | 34 | 17029 | 2761 |
UNK,RPS2,CYLD,GPBP1L1,EIF3D,MAGED1,RGS2,EIF1B,UTP25,HUWE1,ZNF746,ANP32A,COPS7B,NAP1L4,COPS8,STAU1,EIF3L,DDX24,PRRC2A,RPS10,BRCA1,RPS9,EIF3G,EIF3A,EIF3H,EIF3K,EIF4ENIF1,NIP7,NSF,USP20,COPS6,SMURF1,CD81,CDK2 |
| 3.156e-05 | -10.36 | Mitochondrial translation termination | REACTOME pathways | R-HSA-5419276 | 87 | 30 | 10287 | 1696 |
MRPL9,MRPL42,MRPS2,MRPS15,MRPL39,MRPS26,MRPL12,MRPL43,MRPS10,MRPL16,MRPS14,GFM2,MRPL19,MRPL50,MRPL2,DAP3,MRPL55,CHCHD1,MRPL27,MRPL34,MRPS27,MRPL54,MRPL48,MRPL40,MRPL11,MRPL21,MRPL13,MRPL3,MRPL32,MRPL57 |
| 3.170e-05 | -10.36 | BROMO | smart domains | SM00297 | 42 | 17 | 9493 | 1367 |
ASH1L,BRD4,KAT2A,BAZ2A,ZMYND11,SMARCA4,PBRM1,TRIM28,ATAD2,SP100,BRPF3,BRD2,BRWD1,BAZ1B,BRD7,BRWD3,BRD9 |
| 3.170e-05 | -10.36 | SANT | smart domains | SM00717 | 42 | 17 | 9493 | 1367 |
DNAJC2,NCOR2,TRERF1,MTA2,MIER1,MYBL2,RCOR1,MIER2,EZH1,RCOR3,TTF1,SNAPC4,MTA1,MYBL1,TERF1,CDC5L,TERF2 |
| 3.180e-05 | -10.36 | GSE46025_WT_VS_FOXO1_KO_KLRG1_LOW_CD8_EFFECTOR_TCELL_DN | MSigDB lists | GSE46025_WT_VS_FOXO1_KO_KLRG1_LOW_CD8_EFFECTOR_TCELL_DN | 159 | 44 | 17377 | 2626 |
HSPH1,ZCCHC8,ACTR3,PRKAA1,YTHDF3,AGFG1,ELMOD2,SCYL2,CMTM6,SSR1,PRNP,CDKN2C,SUV39H2,PTPN11,ARL6IP1,PDS5B,TRA2B,FOXN2,FAM76B,RNF19A,ATF2,CSNK1G3,MYO5A,MORC3,COPS8,MBLAC2,NUDT4,RNF25,EZR,ATXN1,WIPF1,LLPH,PHF6,CDC27,TMEM168,FAM3C,ACLY,ANP32E,ZRANB2,ACADM,SPCS3,YY1,UNC13C,DDX52 |
| 3.182e-05 | -10.36 | EEF1D (eukaryotic translation elongation factor 1 delta) | protein interactions | 1936 | 140 | 42 | 17029 | 2761 |
KARS,MAX,CYLD,RPS6KA1,MCCC1,RPL15,CUL1,CSNK2A1,STMN1,PCBP1,SRRT,APP,KTN1,CDC73,LMNA,GTF2F1,FARSA,SIAH1,HUWE1,PPME1,AKAP8,RRBP1,EEF1D,CCT2,STAU1,FOXK1,BRCA1,ADRB2,PKM,MCM2,ANLN,MATR3,ECH1,EPRS,AHNAK,ACLY,SIAH2,CDK2,SMURF1,CD81,TERF1,POT1 |
| 3.188e-05 | -10.35 | FARMER_BREAST_CANCER_APOCRINE_VS_BASAL | MSigDB lists | FARMER_BREAST_CANCER_APOCRINE_VS_BASAL | 316 | 75 | 17377 | 2626 |
ANKRD27,FAM208B,PNISR,TSC22D3,TMEM41B,NANS,LYN,APLP2,ZKSCAN1,KIF14,BCAP29,TP53BP2,PLCL2,GPD1L,ABCC5,ADCY7,ATP6V1G1,ANKLE2,NRAS,HMGN4,NCK1,LRBA,E2F3,CIRBP,MKI67,ABHD11,GALNT7,OPTN,STOML2,PON2,RBM47,KIF18B,CERS6,CEP55,ANP32E,CLU,CLN3,LONP2,SEPHS2,DAP,PRKAA1,GSPT2,ARFIP2,KIF23,REEP5,MYL6B,LRRC8D,CRAT,FJX1,CLDND1,ACAD8,TTLL12,FBL,S100A6,LDHB,FDFT1,SOCS5,GINS1,ELOVL5,DCAF6,TSTA3,ACSL3,KIF11,CYB5A,RHOB,MAGED2,SYNCRIP,TTC13,PDLIM1,PFDN4,CTBS,DBI,SLC16A1,UBE2C,CDKN2A |
| 3.192e-05 | -10.35 | REACTOME_SIGNALING_BY_NOTCH | MSigDB lists | REACTOME_SIGNALING_BY_NOTCH | 94 | 30 | 17377 | 2626 |
MIB2,CCNC,NCOR2,ADAM17,KAT2A,ADAM10,APH1A,RBX1,E2F3,MFNG,CUL1,B4GALT1,RAB6A,NOTCH2,PSEN1,APH1B,POFUT1,ATP2A2,RPS27A,HDAC7,TFDP1,E2F1,DTX4,SEL1L,RBPJ,MAML1,ARRB2,NUMB,HDAC2,TMED2 |
| 3.192e-05 | -10.35 | GO_DNA_DIRECTED_RNA_POLYMERASE_II_HOLOENZYME | MSigDB lists | GO_DNA_DIRECTED_RNA_POLYMERASE_II_HOLOENZYME | 94 | 30 | 17377 | 2626 |
INTS2,CTDP1,ERCC1,POLR2I,RPRD1A,POLR2G,POLR2L,KAT2A,POLR2K,ZNF768,POLR2D,RTF1,EDF1,CDC73,POLR2A,GTF2F1,TAF2,PAF1,MED10,POLR2J,INTS7,INTS1,TBPL1,CTR9,INTS12,TAF5L,TAF12,GTF2H2,TAF6,RPRD1B |
| 3.192e-05 | -10.35 | GO_PURINE_NTP_DEPENDENT_HELICASE_ACTIVITY | MSigDB lists | GO_PURINE_NTP_DEPENDENT_HELICASE_ACTIVITY | 94 | 30 | 17377 | 2626 |
DDX28,RECQL,DDX47,SNRNP200,DDX24,DHX29,HELB,CHD1L,YTHDC2,DHX9,DHX8,DDX20,BLM,DDX39A,CHD1,DHX15,DHX57,XRCC5,DDX17,DDX23,DDX56,UPF1,EIF4A3,DHX16,CHD3,DDX31,DDX5,RUVBL2,DDX42,DDX52 |
| 3.192e-05 | -10.35 | RBL1 (RB transcriptional corepressor like 1) | protein interactions | 5933 | 80 | 28 | 17029 | 2761 |
AATF,FOXK1,CREG1,E2F3,MYBL2,SMARCA4,IRF3,BRCA1,SNRPD3,FOXO3,LIN9,RB1,NUCB1,SMAD2,CCNA2,KMT5C,GOLGA2,RBL1,E2F4,MAPK6,TFDP1,E2F1,TFDP2,CDK2,E2F2,SMAD4,ARID4A,HDAC2 |
| 3.236e-05 | -10.34 | REACTOME_E2F_MEDIATED_REGULATION_OF_DNA_REPLICATION | MSigDB lists | REACTOME_E2F_MEDIATED_REGULATION_OF_DNA_REPLICATION | 33 | 15 | 17377 | 2626 |
POLA2,PPP2CA,RB1,PCNA,PRIM2,CDT1,TFDP1,E2F1,RRM2,CDC6,ORC1,ORC3,CCNB1,PRIM1,FBXO5 |
| 3.240e-05 | -10.34 | FMNL1 (formin like 1) | protein interactions | 752 | 68 | 25 | 17029 | 2761 |
ARHGAP17,PPP1R12A,PHB2,RAC1,TUFM,TIA1,PLEC,ATP5F1B,TOMM40,VDAC1,ABCF1,HMG20A,APP,HSPA1B,RPL11,XRCC5,SUPT16H,GEMIN5,CHCHD3,AHNAK,CORO1C,TAP2,CORO1A,SSRP1,SRPK2 |
| 3.242e-05 | -10.34 | MRPS30 (mitochondrial ribosomal protein S30) | protein interactions | 10884 | 76 | 27 | 17029 | 2761 |
DDX28,MRPL9,CYLD,MRPL42,MRPL39,MRPL12,MRPL43,RPL6,MRPL16,ARMC8,MRPL19,MRPL50,MRPL2,MEX3C,MRPL55,VPS26B,MRPL27,MRPL34,MRPL40,MRPL48,MRPL11,MRPL21,MRPL13,MRM3,MRPL3,MRPL32,MRPL57 |
| 3.244e-05 | -10.34 | SRXN1 (sulfiredoxin 1) | protein interactions | 140809 | 38 | 17 | 17029 | 2761 |
UNK,ATP6V1B2,PSMD2,THADA,STAT6,UCHL5,TTC9C,PPM1G,ZRANB2,TTLL12,AHCYL1,IGBP1,SSSCA1,TACC3,CFL1,SRPK2,USP34 |
| 3.248e-05 | -10.33 | GO_PROTEOLYSIS | MSigDB lists | GO_PROTEOLYSIS | 1123 | 218 | 17377 | 2626 |
PDCD6IP,ADAM10,UBE2Z,CUL1,USP39,SIRT2,UBQLN2,USP48,CCNB1,UBE2I,BIRC2,PARK7,RNF103,FBXO22,PCYOX1L,PSMD1,RAD23B,SRI,FBXW2,JOSD1,SENP1,RHBDD2,PCBP2,USP34,COPS8,BAK1,PLK1,LAP3,RBX1,APH1A,VHL,TOPORS,AURKB,USP22,CCNF,USP21,STOML2,RPS27A,PSMD8,AXIN1,TPP2,ATE1,ADAM9,VPS4A,COPS6,OSGEPL1,FBXL3,CLN3,ARRB2,PSMC1,LONP2,CAPN1,UBE2D3,TMUB1,DNAJB2,UBXN1,KCTD17,PCSK7,CYCS,ZNRF3,XPNPEP3,APH1B,PSMD9,PSEN1,VPS25,RHBDD1,NPLOC4,WDR48,CFLAR,ATG4A,DTL,RNF121,FBXO7,FBXL7,PIK3IP1,UBE3C,ZRANB1,ERLIN1,MAN1B1,PSMA1,USP10,UBE4B,SYVN1,CYFIP2,MAP2K2,ISG15,PSMB3,FAS,PSMC4,DERL1,CDC27,KLHL15,RBMX,SIAH2,USP32,VCPIP1,CTSA,RNF14,RNF139,CDKN2A,USP7,CYLD,ATXN3,UBR2,PTTG1,MYH9,ANKIB1,RAD23A,USP5,SEC11A,UBXN2A,MDM2,FBXL6,PSMA6,SIAH1,UCHL5,MTA1,KIF14,NSFL1C,SOCS6,PARL,CDKN1B,PDCD2,ANAPC7,TTC3,RNF19A,FAM76B,F2R,HTRA2,RLIM,PRPF19,CPNE1,SEC61B,ERMP1,PSMA8,PSMB7,CUL3,NLN,CDC23,EDEM2,PEF1,PSMB9,USP36,RHBDF2,TAF2,AMZ2,ANKZF1,DNAJC10,CDC16,IDE,PSMD3,UBXN2B,ARNTL,SEL1L,RNF38,UHRF2,CHMP4B,TRIM32,USP11,SMURF1,LTA4H,PITRM1,USP53,LRP8,USP13,ADAM23,OTUD5,TRIP12,CASP6,KLHL21,DAP,SRGN,BABAM1,FAM76A,PAWR,SDF2L1,UBE4A,CSNK1A1,DNAJB9,WWP2,SPPL2A,FBXO3,CAPN2,HERC3,PSMD2,CTSS,KLHL20,HUWE1,GTSE1,COPS7B,UBE3B,FBXL19,RNF5,ADAM17,TNFAIP3,LONRF3,KAT2A,USP42,FBXO9,RFFL,ANAPC2,OTUD3,SPPL2B,FADD,FBXO21,KEAP1,PDCD6,CAPN7,PML,USP20,SPCS3,PREPL,UBE2C,ESPL1,FAF1,ANAPC4,IFI16,DDB1 |
| 3.249e-05 | -10.33 | COPI-mediated anterograde transport | REACTOME pathways | R-HSA-6807878 | 79 | 28 | 10287 | 1696 |
TMED7,USO1,TMEM115,COPA,GORASP1,DYNLL1,ANK3,COPE,DCTN2,COG1,TMED3,ARF1,RAB1A,GOSR1,COPG2,COPB2,ARF4,CD59,NAPG,GOLGA2,NSF,TMED10,ARF5,DYNC1LI2,TMED2,KDELR1,DCTN1,SPTAN1 |
| 3.260e-05 | -10.33 | CEP104 (centrosomal protein 104) | protein interactions | 9731 | 72 | 26 | 17029 | 2761 |
RPAP3,PLK1,HSPH1,SKA3,MAPRE2,MAPRE1,LUZP1,CCDC138,CAMSAP1,ADSL,AP4E1,ERC1,CIP2A,DAPK3,HAUS8,CALM2,DLG5,PCM1,NEK1,UPF1,CCP110,KIF14,GPATCH1,AHCY,TP53BP2,CDC37 |
| 3.260e-05 | -10.33 | NSA2 (NSA2, ribosome biogenesis homolog) | protein interactions | 10412 | 72 | 26 | 17029 | 2761 |
NOL12,NIFK,NOP2,DDX24,GTPBP4,EBNA1BP2,CNTROB,BRIX1,MAK16,RBM4,PABPC4,UPF1,EIF2S2,CCDC86,DGCR8,RPS14,RBM34,TYW5,NOC2L,RPF2,RRS1,ZC3H3,FTSJ3,ZC3HAV1,IFI16,GPATCH4 |
| 3.272e-05 | -10.33 | regulation of RNA stability | biological process | GO:0043487 | 168 | 46 | 17256 | 2622 |
DHX9,YTHDF3,THRAP3,PSMD9,MAPK14,PARN,METTL3,PAIP1,PABPC4,FASTKD3,PSMD2,PSMA6,PSMD1,EXOSC7,METTL14,EXOSC1,AXIN2,DCP1A,ANP32A,YBX1,TARDBP,CNOT6L,PABPC1,SAMD4B,EXOSC6,PSMA8,PSMB7,CIRBP,PSMA1,TBRG4,EXOSC9,FXR1,PSMB9,PSMB3,PSMC4,UPF1,SYNCRIP,HNRNPR,RPS27A,PSMD8,PSMD3,E2F1,KHSRP,YWHAZ,RNASEL,PSMC1 |
| 3.294e-05 | -10.32 | adenocarcinoma | COSMIC cancer mutations | adenocarcinoma | 17219 | 2579 | 17385 | 2587 |
HECA,ZBTB10,ABCC10,HEXB,TGOLN2,CCNL2,FBXO22,EEF2K,THAP4,RAD23B,ATP13A3,DNM2,ZNRD1,FTSJ3,USP34,CCDC57,ERCC1,NRAS,EHMT1,KIF15,HNRNPF,WDHD1,MIER2,DIDO1,MCM2,RAB22A,SMAD2,MID1IP1,RPS27A,MYO18A,OGT,MPV17,COX5A,SMAD1,ZNF75A,ANXA11,SLC25A33,ZNF720,SEC61G,GGA1,MUM1,CCZ1,TRIO,CUTA,RAB23,KCTD17,HAUS4,EIF2AK4,APH1B,PARN,CDC73,MYL6B,ATG4A,TMEM179B,ERV3-1,PDXP,SMC3,C4orf3,GEMIN4,MVP,NUP85,PPP6R1,PABPC1,NSUN4,PPA1,IFRD1,AGGF1,FOXK1,RBM42,GTPBP4,MAP7D1,MRPL16,ELK1,EIF4H,RDH11,MAGED2,KPNA1,ETS2,TYW5,WIPI2,RUFY3,PDLIM5,ACSF2,FAM72D,EXOC3,RHOG,STARD7,VTI1A,C5orf30,INO80E,SLC35B2,LCLAT1,RCOR3,CPNE3,KIAA1147,RBM23,ZNF420,AHCTF1,TBC1D22A,TBC1D14,GMEB1,NSFL1C,SEPT11,ZNF226,GPD1L,ZC3H3,ARL5A,PDCL3,SNX8,ERMP1,EID1,IDH3A,POLR2D,HTATIP2,MEF2D,TMEM147,GSTCD,TANC1,MAT2A,VPS26B,CORO1C,NSMCE2,CAMKMT,PPP5C,PITRM1,TUBB,COMMD10,ZNF445,SRSF6,HABP4,CCM2,FLOT1,BTN3A1,ATG2B,ABHD14B,PPP1R3B,GOLM1,ZBTB45,HUWE1,ZNF260,NAA50,ANXA5,LTN1,KANSL2,UBE3B,NAP1L4,ZNF710,ST8SIA2,RPL22L1,MED22,SPTAN1,STAU1,DDX24,TCTEX1D2,TACC1,MRS2,LDHA,HEBP2,LLPH,C14orf132,RAB3IP,TTC33,PICALM,SH3BP5,SLC19A1,ACOX1,FAM3C,AEN,PARP10,YWHAH,THAP5,GPATCH4,FAM129A,TRIM11,YTHDC2,SNX15,RBM8A,ENSA,NENF,SND1,RUFY1,TRIM65,ZER1,PRNP,KRR1,RAB8A,NUP210,NT5DC1,NOC2L,EIF5,TACC3,RYBP,VPS13B,PTPN18,MIOS,SNRPB,MBLAC2,CDC6,UTP3,PBRM1,ODC1,USP21,TRAM2,FBXO28,BCL7C,ARRDC1,ADAM9,DVL1,NUMB,ZNF564,FUBP1,C1orf74,CTU2,PARP12,ZCCHC9,CENPF,LAMTOR3,CHCHD2,NCKAP1,LYRM2,RSAD1,TNS3,SUB1,RINL,SSBP3,KIF13B,MBD2,XPA,AHCY,RBM3,GLE1,MRPL48,LRSAM1,HDHD2,NTPCR,NSDHL,AMD1,CAMSAP1,ZNF761,METTL22,ICAM2,STYXL1,APPL1,BBS12,ANKRD46,RXRB,SDHB,PCM1,GALNT2,TMEM168,NLRC5,RUVBL2,MYO9A,BTBD10,CCNB2,USP7,GLT8D1,RPLP2,SUCLG1,ARID2,TMX4,SLC2A1,ATP6V1B2,PCBP1,LYN,BCAP31,VAV1,TMEM69,MRPL50,PSMA6,ZNF473,ZNF302,BRPF3,TARDBP,BCAP29,CTDSP2,PRPF19,PPIF,KDM3B,MND1,CLCN3,BIRC3,RAB7A,ANKRD33B,PPIE,CHMP2B,VDAC1,EIF3H,TMEM201,GLOD4,IDE,DHX16,UHRF2,XRCC3,CHMP4B,PARD3,BCL2L12,C19orf53,MCM10,KLHL21,PDAP1,CDCA8,TMX3,GTF3A,ARF1,SLC12A9,TUBGCP2,DNAJB9,HOMER1,WBP1L,POLR1B,RNF5,RBM15B,PPAN,RHOA,RPRD1A,BTAF1,TOP3A,ARHGEF12,PCGF1,DDX23,RAB18,CACNB1,TRIM26,PDCD6,ATP6V1D,L3MBTL3,FAM110A,NEIL3,CTBS,BBX,IMPDH1,TAF12,NR2F2,PGAM1,HIPK3,IFI16,TXN,NUP188,H2AFZ,PNISR,TMEM203,PRKCSH,USP39,UBE2I,PARK7,SLC25A37,ASPHD2,ZNF428,RAB4A,TRA2B,SUCLG2,CISD2,TAF5L,SMARCE1,ZNF800,CDC5L,ZNF524,SGCE,OSBP2,NSUN2,USP22,CLNS1A,EIF3A,ZMYM3,DOT1L,IWS1,ANKRD10,WAS,KIF18B,TPP2,C1orf109,ZMAT3,FAM72C,B4GALT2,PRPF38B,RECQL,C9orf78,EWSR1,GADD45G,RRM1,ACAP1,B4GALT1,CYCS,FAM136A,SUPT7L,TMEM165,CNOT3,NPLOC4,SPAG5,WDR48,RTKN,CEP104,EXOSC7,KLHL5,LRRC8D,PPP4R1,MSH2,PIGG,FBXL7,OSTF1,MRPL40,TNRC18,SYTL3,FAM171A1,APOL1,EIF5A,GCC2,PRIM2,ELL2,RDH10,MFNG,RPS24,GORASP2,CAPZA2,ADRB2,CCT8,MTR,PHF6,PFDN5,SLCO4A1,TTC13,GOLGA2,RBMX,MED15,PIAS2,APPL2,SAMD8,CDKN2A,NUDT3,ZNF511,ATXN3,RAF1,KIAA0232,C2orf49,CD320,EPM2A,CCNA2,MTMR4,BRI3,TP53BP2,AQR,RBM12B,ILKAP,CDK12,SAP30,BRD4,DRAP1,NARF,LRRC8A,ELP4,ABHD11,PKMYT1,ASB13,SERP1,TRIM28,SUPT16H,EIF3K,CHMP4A,CBWD1,ATF6,XRCC4,ADAM23,PRPF4B,NDUFS1,DEPDC1,MECP2,SECISBP2,HMG20A,WWP2,JAKMIP1,SLC25A36,CCNK,DNAJC8,ELP5,AXIN2,CITED2,JMJD4,ANKRD37,KAT2A,TMEM126B,RABIF,ADSL,PACS1,BMS1,KCNQ1,OTUD3,ARSK,MACF1,KIF11,KLF6,COMMD4,SMAP2,FADD,SH3GLB1,MYO1F,CBX3,TMEM127,INF2,PPP1R11,DUSP11,DDX5,WDR62,TAF6,ESPL1,PURA,DDB1,DEF6,IPO4,FAM83G,UBL3,NAT9,PIGM,LYRM4,GPR132,UBE2Q1,PTP4A3,BRIX1,MRPL19,ZNF696,SF3B2,PCYOX1L,CDC42,SYNM,GOT2,JAZF1,HADHB,RPF2,SLC35C2,CNNM3,CARM1,SRPK2,WDR41,LARS,ZCCHC10,CCDC138,LRBA,TMEM216,SUMF2,KMT2C,OGFR,PRPSAP1,ASF1B,RPL37,MAN2A2,EIF4ENIF1,NIP7,U2SURP,MIA2,ZNF268,VPS4A,ATP6V0E1,PPP1R2,PM20D2,XPNPEP3,RGS2,LYAR,FAM89B,POLR2I,TRAFD1,SUGP2,GBA,EIF2A,SYVN1,CCDC71L,DAPK3,ARHGAP15,MASTL,UAP1,NFIL3,FN3KRP,YWHAZ,CTSA,TMEM14A,TOB1,TSEN15,ADNP2,TCF12,PRKAB1,MDH2,SMARCA4,ORC1,RRN3,UBXN2A,IARS,CD3EAP,KIF14,EXOSC1,CS,CLTB,DNAL4,CSTF1,POU2AF1,UBQLN4,NXT1,HPDL,PGGT1B,SELPLG,SMU1,ATXN1,GLO1,OGDH,BICD2,CADM1,EDEM2,HERPUD2,TOLLIP,FANCE,MBD3,PDHX,RPS9,ALKBH6,SURF4,DUS3L,ARNTL,ANP32E,FKBP5,TMEM101,CCDC125,ABCA1,PDCD2L,GCLM,RAE1,DCTN2,NUP54,CHIC2,PAWR,MXD4,DCUN1D4,PIP4K2A,XPR1,FERMT3,KIF5B,KLHL20,SEC24C,RRBP1,ARHGEF2,ANP32A,LDLRAD3,C12orf75,STAT3,MYO5A,NIPAL3,AMPD2,TXNL1,PHF20L1,DCAF6,FAM49B,TMEM39A,ATP2C1,RFFL,COG1,RCOR1,PRMT2,TFEB,LEMD2,UPF1,ELMO1,ZC3H7B,DTX4,ZMIZ1,TERF1,HRAS,CCDC93,FGFR1OP,TMED7,PIGQ,AGPAT1,CNTROB,PPP1R16B,MIS12,GSDMB,TTC9C,PDS5B,NUP153,SENP1,PGAP2,TMEM115,PLEKHM3,DCUN1D5,PLEKHF2,BRMS1,PWWP2B,TRIM47,WDR11,AXIN1,SMG9,TRIM52,LONP2,NDUFV2,PHF23,CERK,SLC4A2,EZH1,ITGB5,LMNA,MCTS1,DDX56,EIF2S2,SLC38A5,FOXN2,CARS2,PRRC2A,C16orf72,RB1CC1,ZMYND11,PGS1,MYBL2,UHRF1BP1,SRSF5,MPG,MATR3,CYB5A,NCDN,POLR2J,SETD3,TEX30,PTAR1,CNOT6,NDE1,EGLN1,ZNF207,ANKRD27,PPP1R37,ABCA3,SARNP,IVNS1ABP,RMI2,MON1B,TMEM97,NIT2,NUF2,ZNF267,TCF19,TMEM161B,KTN1,APP,PRKD3,CLUAP1,ATP2A2,UTP18,GRSF1,DUT,ZCCHC2,ANAPC7,RNF19A,FAM76B,CLN6,TMEM9,GCC1,RNF169,ADCY7,ATP6V1G1,ENPP4,RNPS1,CDCA2,FKBP3,GPR137,DDX17,CHCHD3,PEX5,CDC16,HIPK2,MBOAT1,TICAM1,PDXK,ZBTB11,ANXA6,TMBIM4,GMCL1,UBE4A,IL21R,ETS1,WRB,ZNF92,PNO1,CAPN2,ADD3,SUV39H2,TTLL12,TPCN1,TMX1,HNRNPM,LYPLA2,MFSD12,LDHB,PPP3CA,NUDT8,POLK,JTB,EMP3,MTMR12,ZP3,PDE3B,KIF18A,CCDC6,WNT5B,MAPK6,LY75,C4orf46,SLC25A19,RGL1,PSAP,WDR76,IGBP1,FAF1,SNAPIN,COX15,AGRN,THOC1,GNPDA1,GPBP1L1,PPP1R15B,CSNK2A1,EBNA1BP2,GIT2,BIRC2,ATPAF1,DLG5,ABL2,XRCC2,ZFYVE27,MCMBP,PTPRK,CDC37,METTL1,SP3,EXOSC6,HARS,GMFB,ESYT1,ANLN,RAB5B,RHEB,DPYSL3,TBC1D17,TIMM13,CDCA4,TONSL,NRM,NAGLU,ACTB,ZNF45,TMUB1,CTCF,ASAH1,DOCK11,CRLF3,ASXL2,LRRC14,NUS1,SLC27A4,AFF1,MDFIC,MAML1,CYTH1,NQO2,UTP15,EIF2AK1,EIF4G2,ZDHHC3,MOSPD3,ITPRIPL1,CDC27,SNAP23,TBPL1,PRMT7,KCTD7,NDUFA5,CYLD,UGP2,DYNLL1,COPE,HCFC1R1,ZADH2,GGPS1,RPAIN,RAD23A,ABRACL,ATP6V0B,PDK2,STRBP,DUS4L,MRPL34,PDCD2,SAP30L,CLPTM1,SLC39A9,RPL29,RPL35,BTG2,DNAJC9,FRAT2,MTMR6,NFATC2,KDM1B,ARL5B,USP36,CCDC127,MRPL2,ATP1A1,CLK3,MAFK,PSMD3,NDUFA11,CEP55,ZNF436,DNAJC17,NCOA1,SLC25A39,ZC3HC1,ZNF146,ATXN7L2,CDC40,SMAP1,GOLIM4,RRP15,DAP,GNE,SMC6,ARFIP2,NKRF,CHAC2,BZW2,WRNIP1,TMA7,SS18L1,CENPM,PTGES3,CAMK2G,MLEC,ZNF202,PPWD1,FAM50B,RHOT2,NEU1,TPD52L2,GOLGA7,TWSG1,PGRMC1,GLG1,FAM126A,RPS6KC1,UBE2C,PPCS,NDUFB6,TMEM41B,ZDHHC8,PLXNA1,CCNB1,SLC20A1,COMMD6,ABHD14A,POLR3K,C14orf119,ASAP2,SNUPN,CNPY4,PLCL2,TFG,SEH1L,ATG9A,PBK,MKI67,DDX20,AMDHD2,GALNT7,SLC17A5,CCNF,FOXRED1,RBM47,PTER,WDR4,DHTKD1,TRAF5,HDAC2,PWWP2A,HSPH1,LIME1,MAPRE1,CHTF18,ADO,KIF23,SLC35B1,NOTCH2,PMF1,COPG2,JMY,NDUFAF6,FKBP1A,SLC31A1,SNX18,ATIC,CTPS1,ATP6V0A2,PIKFYVE,RNF135,LPCAT1,EEF1D,TMED2,FTL,PHF10,DDX28,ZNF84,SIGMAR1,PIP4K2C,FAM133B,RIT1,PLEC,KDM3A,SF3A2,FAS,EPRS,ZNF777,TMEM54,QARS,PPP3R1,TCOF1,NRBP1,CABLES1,DNMT3A,RWDD1,CKLF,TRIP10,SF3B1,RPS6KA1,CAST,SUZ12,RAC1,GPR89A,OLA1,SNN,GNB2,FLAD1,APLP2,KDM2A,TNPO2,CDKN1B,TALDO1,GPX4,ATP13A1,RFC3,MAPRE2,ERF,CUL3,SLBP,KIAA1586,H2AFV,POLG2,GAR1,PSMB9,DHX57,NSA2,HSPA4,MRPL55,JAK1,TBL3,GOLGA8A,SEL1L,H2AFX,KLHDC4,B4GALT3,PDCD11,ATMIN,POLQ,POU3F2,OTUD5,NCOR2,ANKRD13D,PKP4,SCAMP3,BABAM1,CDCA3,SLC25A12,BLM,TMCC3,GTF2F1,RPL17,CRAT,AHSA1,PRC1,UPF2,COPS7B,SLC38A10,CNOT6L,CNPY3,UBE2M,IFT46,TMEM160,TSHZ1,ZFP64,STRIP1,DENND4C,DENND1B,WDR18,RPL8,ILF3,LRRC1,RHOT1,MARK2,TSR2,ECH1,PRDX1,PLD3,NUCB1,GNA12,FBXO21,C1orf131,PRDX3,PFDN4,HNRNPH3,STX18,TFDP1,KHSRP,ASNA1,CPEB2,SSSCA1,BYSL,VPS29,S100PBP,MIB2,IER2,PTMS,NOP2,UBN1,DCAF15,NF1,FLYWCH2,ALKBH5,MOGS,UBE2Z,TAF6L,BECN1,MAPK14,SNAPC4,RNF103,BCAT2,MBD4,C18orf32,METTL14,IMPAD1,ZNHIT6,RCSD1,PHTF1,SRI,KIF22,ZBTB22,NFU1,OGG1,TRIM14,ELOF1,COPS8,FYTTD1,TRIM8,RRM2,SOX4,ABHD5,UBTF,CXXC4,PAF1,UEVLD,SPATA2,PQBP1,IARS2,ATXN2L,GALNT10,STARD3NL,RPS15,PIGN,AGTRAP,CIB1,XPO7,SRRT,ZNF449,CAPZA1,GLTP,BCL2,KIFAP3,N4BP2,HP1BP3,VOPP1,THNSL1,ISG15,CAND1,C22orf46,GNAS,TSC1,RBM25,CDCA5,ZFP90,NANP,RBBP4,ZBTB24,SMARCD1,MBD1,WASF2,MMACHC,TOMM20,IFI27L1,GNPNAT1,MPHOSPH8,HNRNPUL2,CHD1,MEAF6,C2orf68,CCDC50,AKAP8,PARL,RPN2,CHTOP,FAM3A,F2R,SCYL3,TMEM14C,ABI1,HTRA2,MOSPD1,RLIM,FAM172A,ZNF500,PSMB7,NLN,WIPF1,BOLA1,BUD13,NDUFB1,PEF1,EIF3G,BTBD1,TAB2,CHCHD1,TULP3,WDR59,CANT1,SCARB1,GAS2,USP11,SMURF1,TSPAN5,PPP2R2D,CDS2,MAGEH1,MRPL42,EYA1,CDK2AP2,MRPS26,LETMD1,KLF13,HDDC2,RGS1,MAN1A1,FBXO5,GART,PELO,TANK,BRD7,MRPL11,SAMD4B,ZDHHC18,GTF3C6,POLR3GL,WDR81,MEN1,ZNF407,MFN2,COX8A,ZRANB2,SRSF3,MBD6,ATP6V1C1,IDH3B,TATDN1,TSC2,LACTB2,CMTM6,RBM4,ANKRD39,ZNF275,RPL23A,CDKN2C,NAPG,USF1,DNAAF2,MECR,AP1M1,UPRT,CRY2,ECD,RNF26,TIPARP,LRRC59,ANKRD9,MGAT5,RHBDD2,BAK1,ZNF559,RHOBTB3,GABPA,NUTF2,WBP1,GINS4,ARF4,KRIT1,BOLA3,AHNAK,RAD18,PDRG1,RNASEL,CHPF2,OAZ1,SMNDC1,PDCD4,NXT2,HIVEP3,KIAA0100,CLSPN,RHOC,DHX9,PDCD7,PSMD9,HAUS2,COPB2,CD59,TFAP4,RNFT1,RIMS3,MEGF8,FBXO7,EFTUD2,MRPL21,CPSF4,PHKG2,LUC7L2,SRSF11,EIF3L,MTA2,TYW1,USP10,ITM2A,SSR2,BCLAF1,MTX1,SFXN5,FNTA,PDLIM1,TXNDC16,TMEM159,ZNF830,MRPL3,ALS2,FAM72A,TRIM41,KARS,NQO1,POC1A,PTTG1,ANK3,TPX2,TBC1D13,DAZAP2,STMN1,GLRX3,C19orf48,CBWD5,REPS1,ABHD16A,FBXL6,SH3BP1,MTA1,UBA5,CLCN6,INTS12,C8orf59,RPRD1B,SZRD1,CGGBP1,CPNE1,SEC61B,POLR2L,FAM118B,GOPC,CRNKL1,E2F3,CIRBP,RPL38,PFKFB3,GORAB,RAB1A,GIGYF1,TMEM184C,PPP2CA,KIF2A,CCDC14,LSM6,RNF38,DMWD,SNRPG,CENPBD1,USP13,MZT1,ZFP91,TRMT6,IP6K2,WDR5,SLC25A43,IFT27,PMVK,RRP36,NEIL2,SRXN1,RPA2,PSMD2,CLIC4,PDCD10,ITGB8,CBWD2,COQ4,ARF5,ARHGEF1,FBXL19,GTF2H2,TTPAL,UTP20,MAGT1,GPS2,DBI,MRFAP1L1,SSNA1,CD81,TMEM131,WDR13,FANCI,PAPOLA,CREM,FANCL,TET3,GLIS2,IL6ST,INTS1,POP7,SLC44A1,MTPN,ASB6,PLK1,RPP25,SEPT9,CELSR2,RBX1,APH1A,RAD51AP1,ZBED5,CKAP2L,PSMG1,UBE2V1,IL12RB1,EAF2,KRTCAP2,LUC7L,LSG1,NECAP2,C1orf122,TRIM4,ALG3,AGPAT2,CHD3,ZNF367,E2F4,PRPF4,KPNA2,BEND6,CLN3,DNAJC30,FAM208A,NGLY1,POT1,MYL12B,CCDC137,RMND5A,HJURP,PHB2,FAM53C,DNAJB2,NKD2,SDC2,KLC1,CDK13,ADCK5,COX4I1,RAB6A,DNAJB1,ARID1B,C1GALT1,MLX,UBE2Q2,CCP110,ZNF746,ARL6IP1,CTR9,NIPSNAP1,ABHD2,DCAF8,ACSL3,LDB1,MAP4K3,ARMC8,RBM38,IRF5,NMT2,RPL36,HAUS8,MBIP,ORMDL2,COX7A2L,ZDHHC7,FAM122A,SIL1,DTD1,UNC13C,BCCIP,SART1,TRAF7,NDUFAF2,TOR1AIP1,ZNF416,LAGE3,TM9SF3,ZFYVE21,RRAGC,ZNF121,OIP5,NRF1,WDR44,PIN1,PPME1,EFCAB11,RPAP1,CABLES2,TOP1MT,LMAN1,AHCYL1,STRAP,SPSB3,ZNF583,SNX25,ARHGAP17,POLR2G,KIAA0040,ZNF780B,PPT1,NUP155,DCLRE1C,MRPS14,RHBDF2,SUGP1,RBL1,FASTK,UBXN2B,STK38,AP1S1,SPRYD4,SLC22A23,H3F3A,CHID1,SMAD4,RAD51D,SLC30A9,NADSYN1,CMAS,UNK,HMGN3,NCAPG,SCYL2,FZD6,HERC3,GTPBP3,CTSS,ORC3,RNLS,YTHDC1,ACP2,CSRP1,HMGN5,METTL5,ABCF2,TUFM,RANGAP1,PNPLA8,HAGH,API5,ZFR,SEC23IP,E2F1,USP20,TMEM219,RBPJ,MAX,PDCD6IP,LUZP1,GXYLT1,ADAM10,CXXC1,TSC22D3,AP3M2,CUL1,GYG1,NANS,OAT,MYEF2,ANKRD26,PA2G4,NOL11,FIZ1,ZNF200,MARCH2,SLC26A2,SRP72,KLF10,LACTB,CBFB,RFC2,RAB2B,PRIM1,MAP3K4,HHEX,RPS14,LUC7L3,MAP4,MRPL27,BTF3,PTPDC1,CCDC59,NMD3,PTOV1,COX5B,DNAJC5,SCOC,DHPS,POLR2K,ANKH,C16orf87,PRKAA1,VAV2,GSPT2,DLGAP4,TATDN3,PXMP2,PRPF39,PSEN1,ZNF79,PDXDC1,VPS25,NDUFS7,YY1AP1,C12orf10,FAM192A,RPN1,LHX8,ARPC5,ZNRF2,DAPK1,TPST1,PIK3IP1,CYC1,SOCS5,FDFT1,PIGT,WDR1,EMB,ZNF574,C1orf35,EXOSC9,ARID1A,PTTG1IP,C9orf40,FXR1,GOSR1,MAP2K2,TWISTNB,AKAP1,XRCC5,HMGN2,PI4K2A,SEC31A,CAT,DERL1,HSPBP1,MTHFD2,CEBPG,ARAP1,USP32,FAM83D,CABIN1,SMPD4,GPI,CYTIP,TP53RK,REPS2,RAB11B,UROD,SLC39A13,POMP,BCL2L1,NUDT19,DECR1,RALB,SIAH1,LPIN2,ADCY9,SOCS6,MRPS27,TTC3,RNASEH2A,CFL1,ANKLE2,CDC123,OAF,VDAC2,EDF1,ERC1,EML4,AMZ2,ANKZF1,ZNF282,RAD51C,DSN1,DDOST,HINT1,DGCR8,SAFB,HAGHL,LMBR1,RWDD4,FTSJ1,NCLN,BEND3,EYA2,DYNC1LI2,B4GALT5,SLC41A1,MANBA,TKT,FAM76A,CBLL1,ARGLU1,LANCL1,POFUT1,FAM8A1,HEATR5B,HLA-A,EBP,RFWD3,NDUFA2,FUT8,FJX1,BTF3L4,PTPN11,MRPL54,FEM1B,RPL19,CNN2,NDUFA3,MTX2,MSH6,PDLIM2,LONRF3,RFXANK,FBXO9,GUF1,RPL32,ZHX1,OAZ2,NDUFS5,WDR91,GPR89B,HIGD2A,ZBED3,RORB,POLA2,ZNF76,MTX3,COPA,UQCR10,HMGXB3,PHRF1,ABCB10,COMMD5,MAP1LC3B,DST,SIVA1,RAB35,GPATCH1,TCEA1,DRAM2,DEAF1,TRAPPC13,SNRNP200,NCK1,LAP3,VHL,SREK1,ARHGDIB,PITPNB,HSPB11,BRWD1,PPM1G,SH3GLB2,CRCP,BAZ1B,CAB39,ACBD4,STK11,CLU,CHEK2,ZSWIM3,TSTD2,MRPL13,CHPT1,DCAF5,CAPN1,UBE2D3,NSMCE4A,PPP1R12A,ZCCHC8,GORASP1,UBXN1,NACA,C19orf25,PCSK7,EPN1,RPL15,THRAP3,TTF1,QSOX2,PRPF18,NUP205,CHKA,DTL,MED10,ZRANB1,MCPH1,SLC12A2,ATP6V0D1,CSNK1G3,CREG1,NUDT4,RPL6,VKORC1,SLTM,EVC2,KLHL15,SIAH2,SLC16A1,EHD4,SNRNP70,C11orf1,APOL2,N4BP2L2,SNX27,CHMP2A,CORO7,FEZ2,PMS2,UCK2,UCK1,CLCC1,EXT2,MXD1,USP5,HNRNPA2B1,SAP130,NVL,PPP6C,CYB5R1,ZNF770,EBAG9,RNF25,PCGF6,METTL2A,FAM72B,PON2,HNRNPR,HPS5,STAT6,MAPK1,BRD9,TMEM33,PDF,NAT14,DNAJC2,TRIP12,SHPRH,SCYL1,VPS45,MYO9B,GFM2,SPPL2A,FASTKD3,FGFR3,MZT2A,PPIG,ZDHHC13,TMEM99,H2AFY,ATG13,NDUFS8,ERI3,FBL,FRMD8,SLC35A1,MICAL3,TGFB1,B3GALT6,ELOVL5,HEMK1,TIMMDC1,HELB,PSPC1,MIER1,SCFD2,NDRG3,ARL17A,CDK11A,MTMR3,MEGF9,ACAT1,CENPT,PLOD3,RAB3IL1,ZSWIM6,RAB14,ADD1,MRPS15,KDM4A,XIAP,DHX8,GLUD1,ANKRD23,PABPC4,CALM2,CDK5,PSMD1,NEK6,NSRP1,RABGAP1L,SRSF4,FNIP2,KCNAB2,PCBP2,MLST8,PLK3,ZNF672,MRPL43,HSDL1,TOPORS,MCL1,SMC2,PPFIA3,ICMT,SLC50A1,STOML2,LIMK1,ZNF689,PRDX5,ATE1,MLYCD,ATP6V0C,ST3GAL2,FBXL3,TFDP2,E2F2,PFKP,AAAS,DDX42,SSRP1,MRPL9,MRPS2,STRN4,TOP2B,ZNRF3,TMED3,DDRGK1,RAVER2,GNS,INTS7,INPP5A,MCM5,PHF14,ZNF326,UBE2QL1,NAGPA,TIMM8B,ETV3,TSPYL4,TSPAN31,DHX29,TEX10,MAN1B1,RPS10,CBFA2T2,ABCF1,RHOB,LRRC14B,DTWD1,PTPRF,SCARB2,OSBPL11,CCDC86,DUSP3,SLAIN1,MDH1,HEXA,RNF139,SNX14,ZNF296,TRERF1,UBR2,CHD1L,ACTR3,WDTC1,MYH9,CREBL2,NIPA2,PRKACA,SAFB2,ANKIB1,STAM,ARL6IP6,RAB21,SP100,ZKSCAN1,DDA1,NUP107,ANKRD13C,MAVS,CEP63,TMEM136,RBM15,ATF2,DCTN1,SHOC2,PSRC1,MAP4K4,WBP2,ATP6V0A1,NUSAP1,NDUFA7,DNAJA1,TAZ,C19orf54,TAF2,SEC61A1,WDR7,RPLP1,CBLN2,RBMS1,FUS,GEN1,LRP8,COIL,LRCH1,GALK1,ZNF786,RPS2,SESTD1,TRAK1,JMJD6,SIKE1,AKT1S1,KRI1,FBXO3,ERH,GATC,NDUFB4,PPP1R8,PRDM4,GTSE1,GEMIN6,DCP1A,SGCB,S100A6,IMPA2,NUDC,PDPK1,TK1,GUK1,TNFAIP3,GALC,ZNF512,KIAA0930,MRPS10,DDX39A,RPA1,ZNF862,ZNF180,KEAP1,POLE,TATDN2,PITX1,CAPN7,LRPPRC,PML,HMGB2,USF2,ANAPC4,SRM,DDX47,MCCC1,CDC42SE2,S1PR2,CDIPT,SEC16A,SSR1,LIN9,PCNA,ZNF639,TRMU,PIK3R2,ETV6,PPCDC,TXLNA,FAM86C1,MYBL1,MRPL32,CCAR1,ABCC5,PBXIP1,BAZ2A,TLK1,MRPL12,EZR,LNX2,LRP5,BRCA1,PRKRA,STX16,EPB41,OPTN,SEPT1,SOCS4,QRSL1,PIEZO1,OSGEPL1,GLCCI1,NUDT11,NAA60,GEMIN7,SEPHS2,LZTR1,RACGAP1,PPP3CB,B4GALT4,RLF,RAPGEF6,SNRNP25,RB1,VASP,MED8,VMP1,PPIL2,MEA1,TIMELESS,AHDC1,ALDH18A1,TMEM8A,ABCC1,PREB,TRAPPC9,AACS,MEMO1,KRAS,RTF1,UBE4B,NFATC2IP,LY6E,ARPC1A,ZNF174,PSMC4,GOLGA4,SYNCRIP,PALB2,PRPS2,NIPA1,TIGD2,RNF114,FOXM1,MRPL39,XAB2,SUMO2,DUSP22,COMMD8,RPL11,CSDE1,MDM2,CORO1A,MINPP1,METTL9,POC5,DVL2,GM2A,PSMA8,COQ10B,CPOX,TIGD5,SLC26A6,CYP20A1,PRPF3,TXNL4A,RPSA,SRSF1,DNAJC10,SCAP,ZNF700,PLEKHG4B,TIMM17A,TOMM6,FAU,LTA4H,AP2S1,USP53,INTS2,CTDP1,MIF4GD,CDT1,ARID5A,SUMF1,GGA2,AP3S1,CSNK1A1,RMI1,TFRC,PTPN2,STARD9,IRF4,GSTK1,NDUFV1,SLC1A4,CWC27,SLC35B4,DDX31,ABCD1,RPAP3,CNTN5,SNX2,ZMYM5,CCDC34,CHCHD6,BSDC1,KPNA4,CDKN2AIPNL,FBXO41,BIRC5,TFE3,SNAP29,CDCA7L,PKD2,ACADM,CHMP7,SAT2,GCSH,ZNF496,TMEM109,TAP1,YTHDF3,NHLRC3,IKBIP,EIF1B,ELMOD2,KIFC1,DBNDD1,CYB5RL,PARPBP,RNASEK,CDC25B,PRADC1,DNMT1,NOL12,ORAI2,USO1,AKT2,NOL8,GNG7,AURKB,MCFD2,SLC25A5,ZFAND5,MAK16,STT3A,TMED10,PSMD8,EIF2D,ITGB1,PTPN7,UQCRH,RRS1,ARRB2,RTN3,ZNF598,SVIP,DDX58,WSB2,PPIB,MUT,GMFG,HLA-E,NDUFA4,MAN2B1,METTL3,CFLAR,NDUFS4,RNF121,MEX3C,KLF16,HDAC7,DAD1,BDH1,PCYT2,GNAI2,ANKHD1,TERF2,MORC3,KCTD20,SEPT8,DCTD,PKM,TOMM40,PATL1,ADSS,SERTAD2,SERF2,ZFP92,NSF,DCK,ERGIC3,ACLY,LPCAT4,VCPIP1,YY1,PPP6R2,PPP6R3,MAP3K5,RNF14,CDK2,ZC3HAV1,SYS1,ZBTB37,URB2,EIF3D,MAGED1,KLHL18,ADPGK,SLC25A44,AP1B1,SDHA,PAIP2,PHC2,CRKL,MOAP1,TERF2IP,CYHR1,ZNF75D,SHC1,UCHL5,NAA35,TMBIM1,CCT2,CDKN2AIP,MKLN1,HMGN4,LYRM1,GALK2,CDC23,SHCBP1,AP4E1,PRDM11,VEZF1,PPP2R5A,ACYP1,STAT1,PPA2,TRIM32,RHEBL1,R3HCC1L,C1orf112,MRI1,TCF3,BRAP,AGPAT3,MYNN,SDF2L1,SPR,RAB11A,REEP5,FOXO3,MAD2L2,CCDC28A,PIP5K1C,RBM17,MAT2B,PTEN,CENPJ,TAGLN2,OSTC,CREB1,PACS2,NCOA2,SMC4,RNASEH2C,NEK7,NET1,PARP4,TBRG4,ANAPC2,RPL27A,YIF1A,SGSH,HGS,TTLL4,SLC38A7,MFAP1,CCDC69,BRWD3,ESYT2,SKA3,NPHP4,UBE2E2,HNRNPAB,PLXNC1,TMEM184B,ST13,DNAJC24,ZNF107,KIF2C,SLC29A1,AGFG1,SIRT2,FKBP2,USP48,SNRPD3,UBQLN2,CUTC,EDC3,UBLCP1,ZNF804A,RAP1A,THADA,EIF4A3,AP3S2,ATG3,DPYSL2,PPP1R12C,AKR1B1,NDUFB9,JOSD1,RP2,TTC4,TECR,ARID4A,FGFR1OP2,TIMM50,TDP1,DPM1,FOPNL,SLC16A7,WDR82,SLC25A22,STK17B,DHX15,CHAF1A,GEMIN5,COPS6,SASS6,RPS26,PSMC1,SLC12A7,TBC1D12,TM9SF4,ZNF768,UFC1,MED13L,TIA1,MEF2A,EPHX2,PITHD1,RHBDD1,NFATC3,BANF1,BUD31,ZNF335,YBX1,KNTC1,ACAD8,UBE3C,ZNF189,ALDH9A1,KDELR1,TSTA3,CIC,OXR1,PSMA1,TMEM241,SEPT7,NAP1L1,NSMF,ODF2,EXOC4,KIAA1328,NUP62,PITPNA,NAA20,PTDSS1,MZT2B,PDSS2,C7orf26,TMEM106C,IMMT,ASH1L,CHERP,WDYHV1,PLAGL2,CHKB,IRF3,TWF2,PAIP1,ANKRD28,ANKLE1,FARSA,SAR1A,SCAMP4,APOOL,PDIA6,ACSL5,TOR1AIP2,AZI2,GFER,RAD54B,DAP3,TMEM41A,ZNF317,GADD45B,AKNA,REEP4,CBX4,MIF,KIF3B,GOLPH3L,SH2D3A,CASP6,TOR3A,SRGN,DBF4,MFSD10,SAC3D1,CTNNBL1,YIF1B,CLDND1,TTC17,SLC25A1,GINS1,PAQR6,CSNK1G2,TELO2,ADAM17,HMGN1,NASP,ASPM,PPP1R21,PRKAR1B,SYMPK,TARS,SNRPA,MAPK3,HSPA1B,HLA-B,ATAD2,PLAA,ZNF330,OSBPL8,KBTBD7,PREPL |
| 3.335e-05 | -10.31 | GCM_GSTA4 | MSigDB lists | GCM_GSTA4 | 60 | 22 | 17377 | 2626 |
WSB2,PHF10,EXOSC6,FAM172A,ZNF84,TSPYL4,RBM8A,WBP2,USP22,CDIPT,ZFAND5,FOXO3,ABHD14A,DLG5,MTMR3,HGS,BRPF3,BRD2,VPS26B,PPIG,APPL2,TNPO2 |
| 3.335e-05 | -10.31 | MORF_RPA1 | MSigDB lists | MORF_RPA1 | 60 | 22 | 17377 | 2626 |
TMEM106C,SP3,KARS,POLR2I,SNRNP200,NUP188,HNRNPAB,RAC1,DDX39A,PRPSAP1,SDHA,CLNS1A,RPA1,HNRNPA2B1,SYNCRIP,MTA1,PARG,RBMX,RAD23B,MSH2,COIL,HDAC2 |
| 3.336e-05 | -10.31 | Tubg1 (tubulin, gamma 1) | protein interactions | 103733 | 101 | 33 | 17029 | 2761 |
MZT1,COPA,SUCLG1,FOXM1,VAV2,NDUFA4,GLUD1,B4GALT4,TMEM165,SRRT,TUBGCP2,MZT2A,ATG3,COPS7B,SLC25A1,TIMM50,SRSF10,CCT2,NSUN2,TUBGCP5,SLC25A22,PKMYT1,DNAJA1,FXR1,SLC25A5,CCT8,PON2,ATP1A1,PDCD6,RBMX,BBX,MZT2B,IPO4 |
| 3.345e-05 | -10.31 | ubiquitin-like protein ligase activity | molecular function | GO:0061659 | 235 | 60 | 17224 | 2647 |
MIB2,TRIP12,SHPRH,TRIM11,UBR2,XIAP,UBE2Z,CBLL1,BRAP,CUL1,NHLRC3,UBE4A,ZNRF3,UBE2I,ANKIB1,WWP2,HERC3,FANCL,RNF121,MDM2,MED10,CDC42,SIAH1,ZNRF2,HUWE1,PPIL2,LTN1,RNF19A,UBE3B,UBE3C,RNF26,LRSAM1,UBE2M,RNF5,RLIM,PRPF19,LONRF3,RBX1,VHL,RNF25,CUL3,RFFL,ANAPC2,KIAA1586,TOPORS,UBE2V1,SYVN1,UBE4B,RAD18,PIAS2,RNF38,UHRF2,PPP1R11,TRIM32,SMURF1,RNF14,UBE2C,RNF139,ZNF598,RNF114 |
| 3.348e-05 | -10.30 | RC3H1 (ring finger and CCCH-type domains 1) | protein interactions | 149041 | 172 | 49 | 17029 | 2761 |
PPIB,CMAS,RPS2,SNRPD3,SEC16A,CNOT11,CNOT3,RPL11,RPL23A,SF3B2,HNRNPA2B1,SPINDOC,FARSA,ERH,RPN1,ZNF326,RBM3,FBL,CNOT6L,LUC7L2,EEF1D,STAU1,RPL29,SNRNP200,RPS10,RPL8,RPL38,CIRBP,RPS24,UBE2V1,SMC2,EDF1,RPL27A,SLC25A5,KIF11,LUC7L,TRIM28,MATR3,DDX17,CNOT9,HNRNPR,STK38,RPS14,ZC3H7B,OGT,ZRANB2,FUS,ATP5F1A,FAU |
| 3.384e-05 | -10.29 | CHNG_MULTIPLE_MYELOMA_HYPERPLOID_UP | MSigDB lists | CHNG_MULTIPLE_MYELOMA_HYPERPLOID_UP | 52 | 20 | 17377 | 2626 |
RPS15,RPL29,RPL35,RPLP2,DHPS,RPL15,RPL27A,EIF3G,RPS9,RPSA,RPL36,EIF3K,RPL37,RPL32,QARS,RPS14,RPLP1,MRPL34,SNRNP70,FBL |
| 3.384e-05 | -10.29 | SENESE_HDAC1_TARGETS_UP | MSigDB lists | SENESE_HDAC1_TARGETS_UP | 418 | 94 | 17377 | 2626 |
FAM208B,MAX,COPA,ADAM10,SF3B1,TOR1AIP1,YTHDF3,TM9SF3,CDC42SE2,BCL2L1,SLC25A37,PRNP,CREM,PAPOLA,AHCTF1,RAB35,IL6ST,ATP13A3,LMAN1,MOB1A,GM2A,MOSPD1,USP34,PPIF,LARS,TRIM8,BIRC3,APH1A,FOPNL,TAOK1,EZR,MCL1,OGDH,KDM1B,STX16,CBFB,SUPT16H,ZNF317,TMEM41A,SEC61A1,DUS3L,UEVLD,CERS6,ITGB1,CANT1,ANP32E,ZMAT3,DDX42,NXT2,KLHL21,SRGN,TRIO,DHX9,RAB6A,AKT1S1,ETS1,SRRT,SCYL2,PIP4K2A,TFRC,DNAJB9,PNO1,RB1,GART,MLX,MEX3C,PTPN11,TMED2,TMX1,RPAP3,PRIM2,TNFAIP3,GALC,USP10,BCLAF1,PLEC,RPL27A,ZFR,FAS,EPRS,SLCO4A1,KPNA4,CDC27,DUSP3,TFE3,SNAP23,USP32,SLC16A1,C4orf46,FAM126A,YWHAZ,TOB1,IFI16,ESYT2 |
| 3.390e-05 | -10.29 | MODULE_323 | MSigDB lists | MODULE_323 | 56 | 21 | 17377 | 2626 |
ST13,UGP2,POLR2K,TACC1,LACTB,TM9SF3,HMGN3,RAB1A,PLEKHF2,CBX3,TMEM69,NSF,VMP1,HNRNPH3,GMEB1,CAB39,ZRANB2,RBPJ,TTC17,PURA,ATP6V1G1 |
| 3.435e-05 | -10.28 | AP2A1 (adaptor related protein complex 2 subunit alpha 1) | protein interactions | 160 | 114 | 36 | 17029 | 2761 |
REPS2,GPBP1L1,EPN1,MYH9,AP1B1,SEC16A,REPS1,RPA2,UTP25,SHC1,MEX3C,PIN1,DPYSL2,ZNF746,DNM2,GTSE1,AP2B1,CLTB,NAGPA,NUTF2,CAPZA2,RIT1,BRCA1,MCM2,ANLN,PICALM,RPA1,NECAP2,SNAP29,MYO18A,PPP6R2,PPP6R3,ARRB2,NKAPD1,AP2S1,NUMB |
| 3.459e-05 | -10.27 | GO_PROTEIN_PHOSPHATASE_BINDING | MSigDB lists | GO_PROTEIN_PHOSPHATASE_BINDING | 117 | 35 | 17377 | 2626 |
STRN4,ENSA,PAWR,PPP3CB,MAPK14,LMNA,RPA2,SHC1,PPME1,PIK3R2,CDKN1B,BCL2,ANAPC7,MVP,STAT3,PPP6R1,CDC5L,ANKLE2,STAU1,PPP1R9B,SHOC2,KAT2A,KCNQ1,AKAP1,MASTL,CDC27,JAK1,CSK,STAT6,CABIN1,PPP6R3,MAP3K5,IGBP1,PARD3,ANAPC4 |
| 3.467e-05 | -10.27 | MCM5 (minichromosome maintenance complex component 5) | protein interactions | 4174 | 238 | 63 | 17029 | 2761 |
USP7,CYLD,H2AFZ,NOP2,PHB2,SF3B1,HNRNPUL2,COPE,LAGE3,DHX9,MYH9,THRAP3,LANCL1,ORC1,SDHA,APP,FANCI,LMNA,HNRNPA2B1,RPA2,YBX1,CRY2,TCEA1,FBL,ORC3,TOP1MT,MCPH1,MCMBP,CFL1,CDC5L,SNRNP200,MLEC,ILF3,BRCA1,PKM,MCM2,SLC25A5,API5,H2AFV,MATR3,DHX15,GINS4,ASF1B,PRDX1,DDX17,MAGED2,SYNCRIP,HNRNPR,RPS27A,TONSL,RBMX,STAT1,H2AFX,FKBP5,DDX5,ATP5F1A,H3F3A,CD81,DDB1,NUDT3,TUBB,CDKN2A,SSRP1 |
| 3.474e-05 | -10.27 | GSE37416_0H_VS_24H_F_TULARENSIS_LVS_NEUTROPHIL_DN | MSigDB lists | GSE37416_0H_VS_24H_F_TULARENSIS_LVS_NEUTROPHIL_DN | 179 | 48 | 17377 | 2626 |
CCDC93,PHF23,C16orf87,GADD45G,ALKBH5,PLAGL2,TM9SF3,ZNF267,SNN,DLG5,SLC31A1,TNFAIP8,TBC1D22A,PPME1,XRCC2,MEA1,CISD2,CLDND1,TFG,RYBP,TNFAIP3,GUK1,GALC,ELL2,VDAC2,CBFA2T2,CYFIP2,ARL5B,ABCF1,SERP1,DERL1,SH3BP5,SGSH,ATP6V1D,MFAP1,HPS5,NSMCE2,GADD45B,CAPN7,MAPK6,TFDP1,CHMP4B,RBPJ,ZMIZ1,ATP6V1C1,CDK2,NGLY1,PDCD4 |
| 3.474e-05 | -10.27 | GSE18791_CTRL_VS_NEWCASTLE_VIRUS_DC_12H_UP | MSigDB lists | GSE18791_CTRL_VS_NEWCASTLE_VIRUS_DC_12H_UP | 179 | 48 | 17377 | 2626 |
TP53RK,MTX3,SHPRH,GSPT2,MRPS26,UCK2,SIKE1,IL21R,MRPL19,NAPG,NFATC3,GATC,SUV39H2,NOL11,NVL,NSFL1C,MSH2,GEMIN6,GPATCH1,CTR9,SS18L1,TARDBP,SLC26A2,PRADC1,TNRC18,STRAP,IMPA2,DDX28,ULK3,FAM172A,CDC123,MBLAC2,TUBGCP5,CRNKL1,C9orf40,POLG2,TXNL4A,IRF5,TSC1,ZNF180,RAD51C,PDCD6,TATDN2,WNT5B,KBTBD7,MLYCD,TERF1,BYSL |
| 3.474e-05 | -10.27 | GSE22886_NAIVE_TCELL_VS_NKCELL_UP | MSigDB lists | GSE22886_NAIVE_TCELL_VS_NKCELL_UP | 179 | 48 | 17377 | 2626 |
TOMM20,LIME1,LYRM4,ST13,CASP6,DHPS,EIF3D,ACAP1,CREBL2,NENF,DNAJB1,PABPC4,BCAT2,CSDE1,THAP4,GRSF1,MDFIC,RPL19,CNN2,PABPC1,TACC3,ABCC1,LDHB,RPL35,OSBP2,PBXIP1,IDH3A,AMD1,RPL8,RPS10,ITM2A,PRKRA,ODC1,SF3A2,EIF3H,ARHGAP15,RPL36,AKAP1,DAP3,ERGIC3,EIF2D,LRPPRC,FKBP5,TMEM159,CCDC59,TOB1,IPO4,HIGD2A |
| 3.474e-05 | -10.27 | GSE12845_IGD_POS_BLOOD_VS_DARKZONE_GC_TONSIL_BCELL_DN | MSigDB lists | GSE12845_IGD_POS_BLOOD_VS_DARKZONE_GC_TONSIL_BCELL_DN | 179 | 48 | 17377 | 2626 |
FGFR1OP,LYRM4,NOP2,LAGE3,HMGN3,PMF1,RCOR3,REEP5,POLR3K,MYL6B,NAPG,DDX56,POP7,CHTOP,PPA1,WDR41,SPTAN1,USP34,STAU1,CLCN3,SNRNP200,AGGF1,RPRD1A,AACS,TEX10,LDHA,MKI67,USP10,PKMYT1,FAM50B,MCM2,RFC2,COMMD4,TRIM28,PRDX1,RAD54B,SRSF1,DNAJC10,SERF2,SIAH2,COX8A,BAZ1B,MDH1,EHD4,MYO9A,RBBP4,PGAM1,FUBP1 |
| 3.485e-05 | -10.26 | RNF157 (ring finger protein 157) | protein interactions | 114804 | 28 | 14 | 17029 | 2761 |
CNOT9,MAGT1,MRPS2,PSMD8,MEGF8,SMU1,PSMA1,PRPF4,TECR,CDK2,MRPL19,CHD1,BYSL,SLC25A1 |
| 3.487e-05 | -10.26 | purine-containing compound metabolic process | biological process | GO:0072521 | 400 | 91 | 17256 | 2622 |
ADA2,COX15,NDUFA5,PPCS,NDUFB6,UQCR10,OLA1,SLC35B2,EFL1,ADPGK,ATP6V1B2,ATP5PF,SDHA,IMPAD1,ADCY9,PPCDC,NDUFB9,SLC26A2,AHCYL1,CARMIL1,ADCY7,ENPP4,ATP6V0A1,OGDH,NDUFA7,NDUFB1,TAZ,STOML2,HINT1,GUCY1B1,NDUFA11,COX5A,DHTKD1,UQCRH,NUDT11,PFKP,NDUFV2,COX5B,GALK1,NDUFS1,MECP2,RAB23,NDUFA4,COX4I1,CYCS,ABHD14B,ATP5F1B,NDUFS7,NDUFS4,NDUFV1,GART,NDUFA2,NDUFB4,ATIC,MSH2,TPST1,ATP6V0A2,NDUFS8,AHCY,CYC1,NDUFA3,AMPD2,TGFB1,RHOA,GUK1,NUDT4,AMD1,LDHA,ADSL,PKM,ATP5MF,PDE3B,HSPA1B,ADSS,MBIP,ATP5MC3,PARG,DCK,PRPS2,COX7A2L,ACLY,COX8A,IMPDH1,ACAT1,DNPH1,NDUFS5,ATP5F1A,GPI,NIPSNAP2,PGAM1,NUDT3 |
| 3.505e-05 | -10.26 | PSMD11 (proteasome 26S subunit, non-ATPase 11) | protein interactions | 5717 | 145 | 43 | 17029 | 2761 |
CYLD,PRKAA1,PRKACA,PSMD9,KCMF1,APP,UBLCP1,RAD23A,PSMD2,PSMD1,PSMA6,HUWE1,UCHL5,ZFYVE27,BRD7,CRY2,KDELR1,DCTN1,CDC5L,PTPRK,ATG9A,PSMB7,PSMA1,DNAJA1,BRCA1,MCFD2,PSMB9,PSMB3,PSMC4,DERL1,SMAD2,POLE,ZHX1,PSMD8,PSMD3,COX5A,USP20,COPS6,SMAD1,CDK2,ECPAS,PSMC1,SMAD4 |
| 3.508e-05 | -10.26 | GO_CELL_SUBSTRATE_JUNCTION | MSigDB lists | GO_CELL_SUBSTRATE_JUNCTION | 386 | 88 | 17377 | 2626 |
RHOG,PDCD6IP,ADD1,RPLP2,ADAM10,ACTR3,RAC1,MYH9,ZFYVE21,GNB2,GIT2,CPNE3,DST,RAB21,CDC42,DNM2,KIF22,SENP1,PCBP2,CFL1,AATF,LAP3,RPL38,EZR,STX16,RPS9,AHNAK,JAK1,LIMK1,RPS14,CORO1C,ITGB1,RPLP1,ADAM9,ATP6V0C,ACTB,MAPK1,CAPN1,NUMB,PPIB,RPS15,RPS2,ANXA6,PPP1R12A,FLOT1,LAMTOR3,KIF23,SLC4A2,NCKAP1,ARF1,ITGB5,PIP5K1C,CAPN2,CD59,TNS3,FGFR3,VASP,ARPC5,ANXA5,ARHGEF2,ATP6V0A2,RPL19,CNN2,PABPC1,PDLIM2,PDPK1,CYFIP1,ADAM17,DCAF6,RHOA,CSRP1,RPS10,RPL8,RPL6,KRAS,PLEC,MAP2K2,RHOB,HSPA1B,MAPK3,CAT,SCARB2,GNA12,KEAP1,PDLIM1,SNAP23,YWHAZ,CD81 |
| 3.518e-05 | -10.25 | STX12 (syntaxin 12) | protein interactions | 23673 | 97 | 32 | 17029 | 2761 |
NDUFS1,EWSR1,TM9SF4,GORASP1,VPS45,VTI1A,MYH9,ADPGK,BZW2,LMNA,HOMER1,NAPG,ZKSCAN1,TXLNA,ACP2,CCDC138,TMEM216,VDAC2,SCFD2,VDAC1,RAB1A,GOSR1,OPTN,TBC1D17,HGS,GOLGA2,NSF,SNAP23,SNAP29,STX18,ABCA1,ANXA11 |
| 3.520e-05 | -10.25 | GSE15330_WT_VS_IKAROS_KO_LYMPHOID_MULTIPOTENT_PROGENITOR_DN | MSigDB lists | GSE15330_WT_VS_IKAROS_KO_LYMPHOID_MULTIPOTENT_PROGENITOR_DN | 184 | 49 | 17377 | 2626 |
ZNF296,TMED7,NUP188,HMGXB3,CXXC1,TRIM11,CHD1L,STRN4,C19orf25,KLF13,IRF3,GGA2,PDCD7,ANKIB1,SAC3D1,KRR1,EIF4A3,ATG3,EFTUD2,NAP1L4,UBE3C,NSUN4,PREB,SRSF10,RPAP3,COPS8,IFRD1,GABPA,NSUN2,PIP4K2C,SLC25A22,CBFA2T2,COMMD4,MBD3,STK17B,DHX15,EIF3A,LEMD2,UBTF,FBXO21,UPF1,HSPBP1,MRPL55,RBM25,TAB2,SAFB,LRPPRC,SNRNP70,FUBP1 |
| 3.520e-05 | -10.25 | GSE36009_WT_VS_NLRP10_KO_DC_DN | MSigDB lists | GSE36009_WT_VS_NLRP10_KO_DC_DN | 184 | 49 | 17377 | 2626 |
SEPHS2,HIVEP3,TCF12,HECA,THOC1,SRSF6,SLC2A1,UBE2Z,SECISBP2,WDR5,PCBP1,GIT2,RNF103,SRXN1,FBRS,MEX3C,SIAH1,METTL14,TANK,ARHGEF2,FOXN2,TMBIM1,ABCC1,SAP30,ACSL5,KDM3B,ZDHHC18,ADAM17,ETV3,BIRC3,MTA2,PPP1R21,ACSL3,ILF3,RFFL,FAM133B,WDR81,SOX4,MARK2,RHOB,IRF5,SEC23IP,KPNA1,PEX5,HSPA4,SURF4,OGT,ATP6V1C1,SMNDC1 |
| 3.544e-05 | -10.25 | BENPORATH_ES_1 | MSigDB lists | BENPORATH_ES_1 | 354 | 82 | 17377 | 2626 |
DNMT3A,PNISR,HNRNPAB,UGP2,PTTG1,SLC29A1,KIF2C,ZNF267,ORC1,CCNB1,BRIX1,OIP5,FANCL,PRKD3,CCNA2,NOL11,DBNDD1,RABGAP1L,NUP107,PDCD2,ZNF770,CCAR1,USO1,RFC3,RAD51AP1,KAT7,NLN,RRM2,WDHD1,FRAT2,CDC6,AURKB,DIDO1,MCM2,ARL5B,MAK16,GINS4,MAT2A,RAD54B,CHAF1A,SRSF1,PRIM1,HSPA4,BRWD1,KPNA2,FKBP5,CHEK2,LRP8,FUBP1,ADAM23,BCL2L12,MCM10,RRP15,CDT1,TIA1,MAD2L2,PTPN2,HOMER1,GART,MCM5,MSH2,TNPO3,TTLL12,TMX1,MSH6,NASP,PRIM2,AMD1,MRS2,ILF3,RPS24,EXOSC9,FXR1,SNRPA,EPRS,MTHFD2,BIRC5,CDCA5,OAZ2,AEN,SLC16A1,TERF1 |
| 3.555e-05 | -10.24 | GSE17721_CTRL_VS_CPG_4H_BMDC_UP | MSigDB lists | GSE17721_CTRL_VS_CPG_4H_BMDC_UP | 189 | 50 | 17377 | 2626 |
PTMS,NCOR2,NSMCE4A,C19orf53,FAM76A,SMARCA4,NDUFA4,LANCL1,DNAJB1,C19orf48,PIP4K2A,TUBGCP2,BCAP31,XPR1,RPA2,RAP1A,SMC3,STRBP,BDH1,CTR9,TECR,FRMD8,TMEM14C,VOPP1,PSRC1,ERMP1,IDH3A,SLC26A6,RPL38,ZNF574,TMEM147,CDC23,VDAC1,PEF1,ABCF1,MATR3,MAPK3,RPA1,STOML2,QRSL1,MLYCD,ACAT1,TRIM32,GAS2,CCNB2,PTDSS1,RTN3,SSSCA1,NUDT3,PTOV1 |
| 3.555e-05 | -10.24 | LINSLEY_MIR16_TARGETS | MSigDB lists | LINSLEY_MIR16_TARGETS | 189 | 50 | 17377 | 2626 |
BCL2L12,KIF3B,DNAJC5,CDS2,ZFP91,RHOC,TMEM109,KIF23,UBE2Q1,CDC42SE2,DAZAP2,EXT2,PIP4K2A,TFAP4,ZCCHC2,CRY2,MYBL1,LYPLA2,FOXK1,TACC1,ATG9A,TLK1,MRPL43,SLC25A22,PACS1,UBE2V1,C9orf40,ANLN,MACF1,RAB22A,SFXN5,HSPA1B,MFN2,PAF1,PON2,CDCA4,CDC27,LIMK1,KLHL15,SETD3,FASTK,MAP4,H2AFX,E2F1,PPP1R11,FAM122A,MAPK1,NMD3,PURA,DYNC1LI2 |
| 3.555e-05 | -10.24 | GSE43955_1H_VS_20H_ACT_CD4_TCELL_UP | MSigDB lists | GSE43955_1H_VS_20H_ACT_CD4_TCELL_UP | 189 | 50 | 17377 | 2626 |
RMND5A,UBL3,IER2,GPR132,GNPDA1,MAGED1,TRAK1,CTCF,AGFG1,NANS,AP3S1,GGPS1,MBD4,VAV1,APLP2,MDM2,TNFAIP8,FEM1B,AFF1,AQR,CITED2,SLC35C2,RPRD1B,HDHD2,CSNK1G2,PRIM2,AKT2,RAB7A,ABCF2,NSUN2,POLR2D,HTATIP2,SSR2,GORASP2,TMEM147,COMMD4,GFER,RHOB,RPA1,FBXO21,KPNA4,AXIN1,PRDX5,TFDP1,BCL7C,DTD1,RBPJ,MAP3K5,PDCD4,SMNDC1 |
| 3.555e-05 | -10.24 | GSE22886_NAIVE_CD8_TCELL_VS_MEMORY_TCELL_DN | MSigDB lists | GSE22886_NAIVE_CD8_TCELL_VS_MEMORY_TCELL_DN | 189 | 50 | 17377 | 2626 |
RAB14,HECA,MAGEH1,CYLD,CAST,TMX4,SNX15,AP3M2,CBLL1,CREBL2,ETS1,APP,PRNP,CRKL,GTPBP3,ERH,RAP1A,ADD3,RAD23B,EXOSC1,AP2B1,CDKN1B,MDFIC,BCAP29,TAGLN2,CDC5L,ELOVL5,PPP3CA,BIRC3,SEPT9,PBXIP1,EID1,AKT2,TLK1,LDHA,USP10,CBFB,EIF4G2,GLOD4,FAS,SEC31A,ATP1A1,GOLGA7,RBL1,PGRMC1,CAB39,ANP32E,WDR76,REEP4,TSPAN5 |
| 3.558e-05 | -10.24 | chromatin binding | molecular function | GO:0003682 | 536 | 117 | 17224 | 2647 |
ASH1L,DNMT3A,H2AFZ,WDR13,SUZ12,SMARCA4,ORC1,SIRT2,ANKLE1,PCNA,SP100,MTA1,NOC2L,MCMBP,SMARCE1,ATF2,SAP30L,DNMT1,RNF169,KDM3B,SP3,BRD4,CGAS,GABPA,HMGN4,WBP2,MRNIP,WDHD1,WDR82,NFATC2,PBRM1,MBD3,TRIM28,CHAF1A,SUPT16H,TAF2,PAF1,UBTF,HHEX,SMAD2,BRD2,RBL1,SAFB,E2F4,STAT1,ACTB,NCOA1,H3F3A,BEND6,SMAD4,CBX4,HDAC2,POLQ,SSRP1,PWWP2A,SLC30A9,DNAJC2,PHF23,MUM1,MECP2,CDT1,CENPF,PRKAA1,DHX9,CTCF,MEF2A,TOP2B,HMGN3,EZH1,HDGFL2,ASXL2,FOXO3,HMG20A,GTF2F1,NFATC3,SMC3,MBD2,HDAC7,H2AFY,YBX1,NAP1L4,CITED2,TNRC18,STAT3,MSH6,NCOA2,HP1BP3,TSHZ1,HMGN1,KAT2A,HMGN5,MTA2,CIC,ZMYND11,LDB1,ARID1A,MEN1,ELK1,KDM3A,POLR2A,HMGN2,LEMD2,UPF1,ATAD2,POLE,EPOP,RBMX,CDCA5,NUP62,HMGB2,DDX5,CABIN1,RBPJ,RUVBL2,MBD6,RBBP4,SMARCD1 |
| 3.565e-05 | -10.24 | TAANNYSGCG_UNKNOWN | MSigDB lists | TAANNYSGCG_UNKNOWN | 77 | 26 | 17377 | 2626 |
SP3,UBE2D3,PIGN,RHOA,PPP1R12A,ZBED5,B4GALT1,BRCA1,SEPT7,GSTCD,PCGF1,MATR3,RBM4,DHX15,RAD23A,GART,CCNA2,SYNCRIP,CCP110,RBMX,PPIG,NFIL3,SUCLG2,INTS12,CHTOP,ATF2 |
| 3.580e-05 | -10.24 | RAMALHO_STEMNESS_UP | MSigDB lists | RAMALHO_STEMNESS_UP | 194 | 51 | 17377 | 2626 |
GCLM,PPP1R2,MRPS2,SRSF6,CHD1,STAM,PTPN2,RRN3,IARS,RNFT1,IMPAD1,ZNF639,RAD23B,MRPL34,MSH2,PDCD2,SUCLG2,MDFIC,F2R,PPA1,USP10,MRPS10,MAP4K3,GLO1,KRAS,EIF4G2,PRPSAP1,GFER,LSG1,XRCC5,UTP20,KIF2A,EPRS,RAB18,HSPA4,SEC23IP,SMAD2,TPP2,IARS2,ITGB1,ADAM9,PKD2,SRSF3,GAS2,ACADM,SMAD1,YWHAH,MRPL3,ZMAT3,BYSL,GCSH |
| 3.597e-05 | -10.23 | TTTGCAG,MIR-518A-2 | MSigDB lists | TTTGCAG,MIR-518A-2 | 199 | 52 | 17377 | 2626 |
TCF12,KIF3B,CTDP1,MAPRE1,PPP1R12A,IVNS1ABP,ACTR3,XIAP,MED13L,YTHDF3,AGFG1,RAB6A,KCMF1,MAN1A1,ANKRD28,RAB21,NRF1,DAPK1,BRI3,BCL2,TARDBP,SEH1L,CGGBP1,SRSF10,SRPK2,SLC39A9,MLEC,TIMP2,TACC1,C16orf72,MEMO1,FAM133B,PBRM1,RHOT1,CBFA2T2,ZFAND5,PICALM,RAB22A,SLTM,DHX15,PHF6,PTPRF,KPNA4,RBM25,SURF4,HNRNPR,OSBPL8,STK38,CORO1C,CPEB2,DCAF5,DDX42 |
| 3.600e-05 | -10.23 | MODULE_177 | MSigDB lists | MODULE_177 | 99 | 31 | 17377 | 2626 |
UBE2D3,TNFAIP3,HMGN4,PBXIP1,VHL,AMD1,CSNK2A1,ARHGDIB,NUTF2,MCM2,UBE2I,TFRC,RHOB,RGS1,NEU1,SSR1,CBX3,DDOST,JAK1,PTPN7,H2AFX,HMGB2,FKBP5,PTGES3,SCARB1,ALDH18A1,CLN3,EIF5,DNMT1,IFI16,TMED2 |
| 3.607e-05 | -10.23 | positive regulation of viral process | biological process | GO:0048524 | 103 | 32 | 17256 | 2622 |
PPIB,CTDP1,CHMP2A,POLR2K,TRIM11,YTHDC2,DHX9,SMARCA4,CHD1,GTF2F1,RAD23A,TMEM250,TFAP4,SMC3,ZNF639,MDFIC,PABPC1,CFL1,SRPK2,STAU1,POLR2I,POLR2L,POLR2G,RAB7A,PPIE,POLR2D,CHMP2B,POLR2A,POLR2J,CHMP4B,VPS4A,DDB1 |
| 3.610e-05 | -10.23 | RHO GTPases Activate Formins | REACTOME pathways | R-HSA-5663220 | 117 | 37 | 10287 | 1696 |
MAPRE1,RHOC,RAC1,CENPF,CDCA8,NUF2,KIF2C,PMF1,SPDL1,MIS12,AHCTF1,CDC42,NUP107,KNTC1,CENPM,NUP85,DVL2,SEH1L,NUDC,PLK1,RHOA,TAOK1,RANGAP1,AURKB,CENPU,RHOB,PPP2CA,KIF2A,KIF18A,PPP2R5A,DSN1,BIRC5,ITGB1,ACTB,DVL1,CENPT,NDE1 |
| 3.617e-05 | -10.23 | RAF1 (Raf-1 proto-oncogene, serine/threonine kinase) | protein interactions | 5894 | 191 | 53 | 17029 | 2761 |
NPHP4,TSC22D3,DYNLL1,RAF1,EIF3D,PRKAA1,XIAP,BRAP,BCL2L1,PRKACA,GNB2,BIRC2,NPLOC4,CFLAR,OIP5,VAV1,RB1,RAP1A,HUWE1,PIN1,NUP107,MSH2,BCL2,TIMM50,PDLIM2,CDC37,SHOC2,NRAS,BIRC3,PBK,DCAF8,RFXANK,KRAS,DNAJA1,ERBIN,PKM,VDAC1,CCT8,MAP2K2,RHEB,MAPK3,PPP2CA,HSPA4,JAK1,ACOX1,YWHAZ,YY1,MAP3K5,ARRB2,MAPK1,YWHAH,HRAS,PURA |
| 3.621e-05 | -10.23 | JUN (Jun proto-oncogene, AP-1 transcription factor subunit) | protein interactions | 3725 | 277 | 71 | 17029 | 2761 |
CCDC93,CORO7,MAX,TSC22D3,SUMO2,CSNK2A1,UBE2I,MAPK14,APP,OIP5,VAV1,APLP2,MDM2,IARS,PIN1,MTA1,ATF2,SMARCE1,ELOF1,GOPC,KAT7,NFATC2,BRCA1,EDF1,MEF2D,KMT2C,MBD3,HHEX,SMAD2,CHD3,STAT6,ARNTL,STAT1,KPNA2,NCOA1,MAPK1,SMAD4,PPP2R2D,NAT14,NCOR2,EWSR1,NACA,DHX9,STRN4,MEF2A,NKRF,PPP3CB,ETS1,GTF2F1,RB1,CREB1,STAT3,NCOA2,HNRNPM,EEF1D,PPP3CA,RPRD1A,PRRC2A,PRKDC,PACS1,RANGAP1,MACF1,MAPK3,ETS2,CSK,PIAS2,CEBPG,PML,KHSRP,YWHAH,SMARCD1 |
| 3.634e-05 | -10.22 | autophagosome assembly | biological process | GO:0000045 | 60 | 22 | 17256 | 2622 |
ULK3,ATG9A,RB1CC1,RAB7A,RAB23,ATG2B,RAB1A,MAP1LC3B,PSEN1,BECN1,ATG4A,MFN2,UBXN2A,RAB35,UBXN2B,ATG3,NSFL1C,ATG13,WIPI2,SMURF1,WDR45B,PACS2 |
| 3.636e-05 | -10.22 | positive regulation of chromosome organization | biological process | GO:2001252 | 159 | 44 | 17256 | 2622 |
KMT2E,MECP2,CDT1,CCNB1,BECN1,PARN,HNRNPA2B1,RB1,AKAP8,NABP2,H2AFY,CTR9,BRD7,CHTOP,DNMT1,TGFB1,CCT2,ERCC1,KAT2A,NEK7,KAT7,MIER1,CUL3,WBP2,RTF1,BRCA1,AURKB,TRIM28,CCT8,MAPK3,XRCC5,MAP3K4,PAF1,NSMCE2,OGT,PML,RUVBL2,MAPK1,SLF1,POT1,ESPL1,SLF2,SMAD4,TERF1 |
| 3.638e-05 | -10.22 | - | gene3d domains | 3.30.70.330 | 244 | 63 | 8148 | 1295 |
NIFK,EWSR1,HNRNPAB,R3HCC1L,SRSF6,RBM8A,TIA1,SAFB2,PARN,MYEF2,RBM4,PABPC4,RPL23A,RAVER2,HNRNPA2B1,RBM17,RBM23,GRSF1,RBM34,SRSF4,TRA2B,TARDBP,RBM3,RBM12B,RBM15,PABPC1,HNRNPM,SRSF10,RBM15B,SRSF11,RBM42,PSPC1,NOL8,SF3B6,PPIE,HNRNPF,RNPS1,CIRBP,SREK1,SRSF5,EIF4H,EIF3G,SLTM,MATR3,SNRPA,RBM38,SRSF1,RBM25,RBM47,SYNCRIP,HNRNPR,HNRNPH3,SAFB,RBMX,U2SURP,DNAJC17,RBMS1,SRSF3,FUS,SNRNP70,HNRNPDL,PARP10,CPEB2 |
| 3.640e-05 | -10.22 | SRSF2 (serine and arginine rich splicing factor 2) | protein interactions | 6427 | 123 | 38 | 17029 | 2761 |
FGFR1OP,EWSR1,COPE,CUL1,CSNK2A1,CCNL2,RAD23A,HNRNPA2B1,SUB1,EIF4A3,HUWE1,SRSF4,TRA2B,EIF5,CDK12,POC5,DCTN1,CDC5L,SRPK2,SRSF11,YTHDC1,UBQLN4,RNPS1,CUL3,PSMA1,SREK1,SF3A2,POLR2A,SRSF1,CAND1,GOLGA2,ZRANB2,FUS,SRSF3,BTF3,SNRNP70,SASS6,HNRNPDL |
| 3.644e-05 | -10.22 | Transport of Ribonucleoproteins into the Host Nucleus | REACTOME pathways | R-HSA-168271 | 31 | 15 | 10287 | 1696 |
NDC1,NUP188,NUP210,KPNA1,RAE1,NUP107,NUP54,NUP62,NUP153,NUP155,NUP85,NUP58,SEH1L,AAAS,NUP205 |
| 3.676e-05 | -10.21 | SNRPG (small nuclear ribonucleoprotein polypeptide G) | protein interactions | 6637 | 110 | 35 | 17029 | 2761 |
SART1,CDC40,XAB2,SF3B1,CUL1,SNRPD3,PDCD7,SF3B2,CMTR2,EFTUD2,GEMIN6,GPATCH1,AQR,GEMIN4,DNMT1,SNRNP200,RBM42,TACC1,SNRPB,PPIE,SF3B6,CUL3,CRNKL1,DDX20,PRPF3,TXNL4A,SF3A2,SNRPA,CLNS1A,DDX23,CAND1,GEMIN5,PRPF4,COPS6,SNRNP70 |
| 3.693e-05 | -10.21 | NONO (non-POU domain containing octamer binding) | protein interactions | 4841 | 168 | 48 | 17029 | 2761 |
CYLD,EWSR1,MRPL39,HABP4,STRN4,ASAH1,SMARCA4,UBE2I,PARK7,LMNA,RPA2,PCNA,NUP210,RALB,HUWE1,PIN1,ZNF746,CRY2,ECD,ALDH18A1,ZNRD1,HNRNPM,CDC5L,STAU1,PSPC1,SUGP2,CUL3,ATP6V0A1,RRM2,KRAS,TOPORS,GORASP2,SNRPA,PLEKHF2,POLR2A,CHAF1A,RPA1,CAND1,RPL36,SCARB2,PROSER1,H2AFX,COX5A,FUS,ARRB2,CD81,HDAC2,SMARCD1 |
| 3.746e-05 | -10.19 | SP1 (Sp1 transcription factor) | protein interactions | 6667 | 253 | 66 | 17029 | 2761 |
MBD1,LUZP1,FOXM1,MYH9,CSNK2A1,SMARCA4,USP39,CCNB1,MAPK14,MDM2,CCNA2,SHC1,PIN1,DNMT1,STRAP,FGFR1OP2,SP3,DEAF1,KLF10,AATF,GABPA,VHL,E2F3,BRCA1,MEF2D,SMAD2,HINT1,RBL1,OGT,ATF6,E2F2,MAPK1,SMAD4,HDAC2,NCOR2,CASP6,MECP2,ETS1,MYL6B,SRRT,TFAP4,SUB1,RB1,PPIG,TIMELESS,STAT3,DCAF6,PRKDC,LDB1,MIER1,PLEC,KLF6,MAPK3,PFDN5,NAP1L1,ODF2,E2F1,PML,DDX5,NUP62,RBBP4,YY1,CDK2,PURA,IFI16,CDKN2A |
| 3.746e-05 | -10.19 | Late Phase of HIV Life Cycle | REACTOME pathways | R-HSA-162599 | 139 | 42 | 10287 | 1696 |
CTDP1,CHMP2A,NDC1,PDCD6IP,NUP188,POLR2K,RAE1,NUP54,NUP205,GTF2F1,CCNK,NUP210,NUP107,NUP153,TCEA1,GTF2H2,NUP85,SEH1L,POLR2I,POLR2L,POLR2G,ELOA,POLR2D,NUP155,RANGAP1,CHMP2B,POLR2A,NMT2,SUPT16H,TAF2,CHMP4A,POLR2J,RPS27A,NUP62,CHMP4B,TAF12,VPS4A,CHMP7,TAF6,NUP58,AAAS,SSRP1 |
| 3.772e-05 | -10.19 | DAPK1 (death associated protein kinase 1) | protein interactions | 1612 | 53 | 21 | 17029 | 2761 |
ST13,TSC2,IVNS1ABP,CUL3,CAPZA2,BECN1,FADD,MAPK3,KRIT1,PPP2CA,TSC1,MDM2,PDCD6,PPP2R5A,KLHL20,CORO1C,DAPK1,DDX5,MAPK1,PPP2R2D,MYL12B |
| 3.772e-05 | -10.19 | MRPL19 (mitochondrial ribosomal protein L19) | protein interactions | 9801 | 53 | 21 | 17029 | 2761 |
MRPL9,MRPL42,MRPL39,MRPL12,CUL3,CUL1,MRPL16,MATR3,APP,NPLOC4,CAND1,MRPL50,DUSP11,MRPL40,MRPL11,MRPL21,MRPL13,HNRNPDL,ZC3H3,MRPL3,MRPL57 |
| 3.772e-05 | -10.19 | PMS2 (PMS1 homolog 2, mismatch repair system component) | protein interactions | 5395 | 53 | 21 | 17029 | 2761 |
CYLD,CLSPN,PRKDC,NSUN2,SMARCA4,BRCA1,RFC2,COPG2,LMNA,PPP2CA,PCNA,NSF,MSH2,CTR9,XRCC3,KPNA2,RUVBL2,ZNRD1,PSMC1,MSH6,DDB1 |
| 3.780e-05 | -10.18 | Programmed Cell Death | REACTOME pathways | R-HSA-5357801 | 175 | 50 | 10287 | 1696 |
ADD1,CLSPN,CASP6,DYNLL1,MAGED1,XIAP,CYCS,BCL2L1,PSMD9,BIRC2,BCAP31,LMNA,CFLAR,PSMD2,PSMD1,PSMA6,DAPK1,BCL2,TP53BP2,SPTAN1,BAK1,BIRC3,PSMA8,AKT2,PSMB7,PSMA1,PLEC,PSMB9,APPL1,PSMB3,FADD,DAPK3,PSMC4,FAS,KPNA1,FNTA,RPS27A,PSMD8,PSMD3,TFDP1,PPP3R1,E2F1,HMGB2,TICAM1,YWHAZ,ROCK1,GAS2,TFDP2,YWHAH,PSMC1 |
| 3.797e-05 | -10.18 | GENTILE_UV_RESPONSE_CLUSTER_D5 | MSigDB lists | GENTILE_UV_RESPONSE_CLUSTER_D5 | 37 | 16 | 17377 | 2626 |
PKP4,RAF1,JMJD6,PITPNB,ATP6V1B2,STAM,FADD,PNO1,UBTF,MLX,DUSP11,TARDBP,MRFAP1L1,SRSF3,PIKFYVE,MAML1 |
| 3.797e-05 | -10.18 | GO_PH_REDUCTION | MSigDB lists | GO_PH_REDUCTION | 37 | 16 | 17377 | 2626 |
CLCN3,PPT1,RAB7A,ATP6V0A1,ATP6V1B2,ATP6V0B,CLIC4,ATP6V1D,ATP6V0A2,ATP6V0C,CLN3,ATP6V1C1,CLN6,ATP6V0E1,ATP6V0D1,ATP6V1G1 |
| 3.797e-05 | -10.18 | GO_SPLICEOSOMAL_SNRNP_ASSEMBLY | MSigDB lists | GO_SPLICEOSOMAL_SNRNP_ASSEMBLY | 37 | 16 | 17377 | 2626 |
GEMIN5,SART1,SNUPN,SNRPB,GEMIN6,PRMT7,DDX20,PRPF3,GEMIN4,SNRPG,SNRPD3,STRAP,CLNS1A,GEMIN7,SRSF10,PRPF19 |
| 3.825e-05 | -10.17 | MORI_MATURE_B_LYMPHOCYTE_DN | MSigDB lists | MORI_MATURE_B_LYMPHOCYTE_DN | 73 | 25 | 17377 | 2626 |
ZBED3,EWSR1,TXN,SNRPB,UFC1,UCK2,RRM2,SMARCA4,CYCS,KIF2C,BRCA1,SOX4,CCNB1,ANLN,RGS2,STMN1,H2AFV,CAPN2,MTHFD2,PSMD8,MCM5,SLC16A1,HMGB2,CCNB2,PSMC1 |
| 3.830e-05 | -10.17 | RPL21 (ribosomal protein L21) | protein interactions | 6144 | 141 | 42 | 17029 | 2761 |
KARS,RPS15,RPS2,CYLD,RPLP2,RPL15,CUL1,RPL11,RPL23A,LYAR,PA2G4,EIF4A3,RPL17,ZNF746,RPL19,TARDBP,PTGES3,STAU1,RPL29,RPL35,EID1,VHL,CUL3,ILF3,RPL8,RPL38,RPL6,RPS10,RPS24,BRCA1,RPL27A,SLC25A5,RPS9,RPSA,CAND1,RPL36,RPL32,RPS27A,RPS14,RPLP1,ARRB2,RPS26 |
| 3.830e-05 | -10.17 | USP11 (ubiquitin specific peptidase 11) | protein interactions | 8237 | 141 | 42 | 17029 | 2761 |
OTUD5,USP7,HSPH1,MZT1,TRIP12,IVNS1ABP,RAE1,SUMO2,XIAP,MOGS,CUL1,UBE2Q1,XPO7,MAPK14,WRNIP1,FARSA,CS,GTSE1,CRY2,NUP153,POLR1B,RBM15B,NET1,KIAA0930,MIER2,UHRF1BP1,CAND1,XRCC5,KEAP1,PALB2,CDC27,SEC61A1,CLK3,TBL3,PML,H2AFX,STK11,USP11,ZNF598,LRP8,ESPL1,FAF1 |
| 3.848e-05 | -10.17 | GCATTTG,MIR-105 | MSigDB lists | GCATTTG,MIR-105 | 165 | 45 | 17377 | 2626 |
THOC1,MECP2,ALKBH5,TMEM97,YTHDF3,TM9SF3,SLC31A1,NSRP1,CDKN1B,TRA2B,SPTSSA,LDLRAD3,TIPARP,CDK12,HDHD2,CAMK2G,SOCS5,RYBP,SP3,COPS8,PHF20L1,FOXK1,RB1CC1,COQ10B,ERLIN1,LDB1,KRAS,PTTG1IP,GOSR1,EIF4G2,RAB22A,ZFR,EIF3A,SOCS7,CXXC4,KPNA4,L3MBTL3,OAZ2,OGT,PPP3R1,SEL1L,NCOA1,H3F3A,SMNDC1,PRPF4B |
| 3.852e-05 | -10.16 | GAZDA_DIAMOND_BLACKFAN_ANEMIA_ERYTHROID_DN | MSigDB lists | GAZDA_DIAMOND_BLACKFAN_ANEMIA_ERYTHROID_DN | 452 | 100 | 17377 | 2626 |
MAX,NQO1,TOR1AIP1,TWF2,MXD1,BCAT2,DST,AHCTF1,ZNF473,CDC42,THAP4,SIVA1,XRCC2,LPIN2,RAB4A,RPAP1,KIF22,SCYL3,SAP30L,SRPK2,CDC5L,USP34,ENPP4,PLK1,ORAI2,RPL29,PSRC1,CELSR2,POLR2D,MCL1,AURKB,DCLRE1C,AZI2,KRIT1,BRD2,MAP4,H2AFX,RBMS1,ST3GAL2,PDXK,TRIM52,XRCC4,TSPAN5,LONP2,NCOR2,RECQL,PIGN,PPP1R12A,TCF3,GADD45G,NOTCH2,MYO9B,MXD4,SUPT7L,IFT27,LYRM2,PNO1,CFLAR,EBP,KLHL5,KLHL20,RRBP1,FAM89B,FEM1B,H2AFY,GLTP,AHDC1,OSTF1,EEF1D,HNRNPM,MED22,TMEM160,ZDHHC18,ELOVL5,HEMK1,DHX29,FBXO9,MTMR12,CYFIP2,MPG,RPL27A,NDRG3,PICALM,ISG15,RHOB,MFN2,UTP20,DTWD1,INF2,UPF1,RBM25,CDC27,MAGT1,CEBPG,DTX4,PSAP,TAF12,NDE1,PURA,NUDT3 |
| 3.858e-05 | -10.16 | PSMD8 (proteasome 26S subunit, non-ATPase 8) | protein interactions | 5714 | 89 | 30 | 17029 | 2761 |
TXNL1,PSMA8,ASPM,DHX9,PSMB7,PSMA1,PSMD9,PSMB9,KCMF1,ABCF1,PSMB3,UBLCP1,PSMC4,RAD23A,PTPN2,PFDN5,PSMD2,SMAD2,PSMA6,PSMD1,HUWE1,UCHL5,PSMD3,FOXN2,SIL1,CDK2,ECPAS,PSMC1,DVL2,ANAPC4 |
| 3.885e-05 | -10.16 | USP49 (ubiquitin specific peptidase 49) | protein interactions | 25862 | 42 | 18 | 17029 | 2761 |
COPA,SHPRH,SHCBP1,PRKACA,KRR1,ANKRD28,RPN1,MED8,HUWE1,PPM1G,LRPPRC,PDCD2,FKBP5,PPP5C,PPP6R2,PPP6R3,NUP85,PPP6R1 |
| 3.885e-05 | -10.16 | E2F6 (E2F transcription factor 6) | protein interactions | 1876 | 42 | 18 | 17029 | 2761 |
MAX,ZMYND11,PCGF6,MIER2,EZH1,WDR5,COMMD6,LYN,COMMD4,TCF19,COMMD8,APP,CBX3,TFDP1,E2F1,TFDP2,ASB6,RYBP |
| 3.898e-05 | -10.15 | regulation of ATP metabolic process | biological process | GO:1903578 | 90 | 29 | 17256 | 2622 |
PPIF,ATP5IF1,NDC1,NUP188,RHOA,RAE1,PRKAA1,NUP54,PFKFB3,NUP155,CCNB1,TAZ,PARK7,NUP205,NUP210,TIGAR,NUP107,OGT,NUP62,NUP153,BEND3,ECD,STAT3,PGAM1,NUP85,NUP58,AAAS,SLC25A33,SEH1L |
| 3.909e-05 | -10.15 | TFE3 (transcription factor binding to IGHM enhancer 3) | protein interactions | 7030 | 25 | 13 | 17029 | 2761 |
EPRS,EWSR1,PHB2,TFE3,ACLY,RPL38,E2F3,AKR1B1,SMARCE1,SMAD4,TRIM28,EIF3A,TFEB |
| 3.912e-05 | -10.15 | ATPase binding | molecular function | GO:0051117 | 72 | 25 | 17224 | 2647 |
ATP5IF1,ATXN3,TOR1AIP1,UBXN1,NKD2,ATP6V0A1,EZR,TOR1AIP2,UBE4B,SYVN1,SDF2L1,DNAJB1,DERL1,DNAJC10,CHMP4A,RALB,ZNHIT6,RAB4A,ATP6V0A2,PKD2,RUVBL2,FBL,ABCA1,ATP6V1G1,SVIP |
| 3.923e-05 | -10.15 | PSMD12 (proteasome 26S subunit, non-ATPase 12) | protein interactions | 5718 | 106 | 34 | 17029 | 2761 |
TRIM11,EIF3D,COPE,CUL1,PSMD9,KCMF1,UBLCP1,RAD23A,PSMD2,PSMD1,PSMA6,HUWE1,UCHL5,AHCYL1,KDELR1,CDC5L,TXNL1,EIF3L,PSMB7,PSMA1,KRAS,BRCA1,MCFD2,PSMB9,EIF3H,PSMB3,PSMC4,PSMD3,PSMD8,USP20,HMGB2,FUS,ECPAS,PSMC1 |
| 3.929e-05 | -10.14 | GO_ANTIGEN_PROCESSING_AND_PRESENTATION_OF_PEPTIDE_ANTIGEN | MSigDB lists | GO_ANTIGEN_PROCESSING_AND_PRESENTATION_OF_PEPTIDE_ANTIGEN | 170 | 46 | 17377 | 2626 |
KIF3B,HLA-E,DYNLL1,DCTN2,TAP1,KLC1,KIF23,RACGAP1,KIF2C,ARF1,AP1B1,PSMD9,ITGB5,BCAP31,HLA-A,PSMD2,PSMD1,CTSS,PSMA6,SEC24C,AP1M1,DNM2,AP2B1,KIFAP3,KIF22,TAP2,DCTN1,PSMA8,RAB7A,KIF15,PSMB7,PSMA1,KIF11,PSMB9,PSMB3,PSMC4,KIF2A,SEC31A,HLA-B,KIF18A,PSMD8,PSMD3,AP1S1,PSMC1,AP2S1,DYNC1LI2 |
| 3.935e-05 | -10.14 | SA_G1_AND_S_PHASES | MSigDB lists | SA_G1_AND_S_PHASES | 14 | 9 | 17377 | 2626 |
MDM2,NXT1,E2F1,CDKN1B,ARF1,E2F2,CDK2,CDKN2A,CFL1 |
| 3.949e-05 | -10.14 | Bromodomain-like_sf | interpro domains | IPR036427 | 45 | 18 | 18492 | 2768 |
ASH1L,BRD4,KAT2A,BAZ2A,ZMYND11,SMARCA4,PBRM1,TRIM28,ATAD2,SP100,BRPF3,BRD2,BRWD1,KMT2B,BAZ1B,BRD7,BRWD3,BRD9 |
| 3.982e-05 | -10.13 | NGRN (neugrin, neurite outgrowth associated) | protein interactions | 51335 | 35 | 16 | 17029 | 2761 |
PPAN,MRPL50,DDX28,MRPL42,STRBP,RBM42,MRPL39,RBMX,RPL6,CIRBP,DCTD,RBM3,HNRNPDL,ZC3H3,ZC3HAV1,RCC1L |
| 3.982e-05 | -10.13 | MRPL52 (mitochondrial ribosomal protein L52) | protein interactions | 122704 | 35 | 16 | 17029 | 2761 |
DDX28,RPS2,MRPL9,MRPL39,MRPL12,KIF2C,LUC7L,APP,MRPL50,MRPL55,RBM3,MRPL40,RRS1,MRPL13,MRPL3,MRPL32 |
| 3.982e-05 | -10.13 | CDC7 (cell division cycle 7) | protein interactions | 8317 | 35 | 16 | 17029 | 2761 |
PAF1,BRD4,MCM10,CLSPN,RAD18,KMT2E,CENPJ,MCM5,DBF4,ORC1,MCM2,CDK2,TOB1,APP,CDKN2A,CHAF1A |
| 3.982e-05 | -10.13 | SAMM50 (SAMM50 sorting and assembly machinery component) | protein interactions | 25813 | 35 | 16 | 17029 | 2761 |
TIMMDC1,SUZ12,NDUFA4,TOMM40,DUSP22,RHOT2,SDHA,CHCHD3,RAB8A,NDUFS8,CYC1,CLN3,MRPL11,APOOL,MTX2,HNRNPM |
| 3.992e-05 | -10.13 | RUTELLA_RESPONSE_TO_CSF2RB_AND_IL4_UP | MSigDB lists | RUTELLA_RESPONSE_TO_CSF2RB_AND_IL4_UP | 318 | 75 | 17377 | 2626 |
TXN,PDCD6IP,NQO1,TRIP10,SUZ12,FAM129A,TMEM97,ENSA,PTP4A3,NIT2,CREBL2,TBC1D13,PLXNA1,PPP1R16B,BCAP31,TNFAIP8,GOT2,DPYSL2,GRSF1,IL6ST,TFG,MOB1A,GM2A,METTL1,BIRC3,MAP4K4,CIRBP,NARF,PSMG1,OPTN,TMEM184C,JAK1,RBM47,CERS6,GADD45B,TRAF5,ATP6V0E1,HDAC2,GCLM,CDS2,PPP1R12A,B4GALT5,TCF3,SDC2,MED13L,TIA1,IL21R,TFRC,CFLAR,CD59,TNS3,IRF4,SLC1A4,MCM5,DAD1,TPST1,MAP3K14,MTX2,ZDHHC18,CYTH1,CSRP1,CREG1,NET1,ACSL3,PRDX1,CYB5A,RDH11,GNA12,WNT5B,LY75,MDH1,RGL1,ATP6V1C1,NDE1,CD81 |
| 3.997e-05 | -10.13 | WANG_CLIM2_TARGETS_DN | MSigDB lists | WANG_CLIM2_TARGETS_DN | 175 | 47 | 17377 | 2626 |
WSB2,MRPL9,RRP15,TSC22D3,MED13L,B4GALT1,MYNN,SLC25A44,FARSA,MEX3C,SP100,RNFT1,UTP18,RAD23B,RP2,NAA35,NSUN4,IFRD1,FOXK1,PRIM2,DPM1,NEK7,CYP20A1,GTPBP4,TUBGCP5,GORAB,TOPORS,CAPZA2,GALNT7,API5,BSDC1,ISG15,RDH11,FAS,RAD18,CCDC86,PFDN4,DUSP3,STAT1,AP1S1,ATE1,BTBD10,TATDN1,RNF14,COIL,ATP6V0E1,MYL12B |
| 3.997e-05 | -10.13 | GSE17974_0.5H_VS_72H_IL4_AND_ANTI_IL12_ACT_CD4_TCELL_UP | MSigDB lists | GSE17974_0.5H_VS_72H_IL4_AND_ANTI_IL12_ACT_CD4_TCELL_UP | 175 | 47 | 17377 | 2626 |
C9orf78,ZBTB10,HECA,TMEM184B,SRSF6,PRKAA1,ASAH1,ADPGK,RAPGEF6,REPS1,CHD1,JMY,DNAJB9,MOAP1,AHCTF1,SYNM,SNX18,PRDM4,ZNF746,MVP,CDK12,NAGPA,SAMD4B,ETV3,RB1CC1,COQ10B,BTG2,NOL8,RNF25,MTMR6,DDX20,SOX4,CDK11A,ABHD5,GOLGA7,SPATA2,ZHX1,TPP2,STK38,RNF38,DUSP11,WDR91,CHMP7,BRD9,SMURF1,ATMIN,ADNP2 |
| 3.998e-05 | -10.13 | GO_PROTEIN_TRANSPORTER_ACTIVITY | MSigDB lists | GO_PROTEIN_TRANSPORTER_ACTIVITY | 95 | 30 | 17377 | 2626 |
PGAP2,TOMM20,USO1,SEC61G,MCL1,XPO7,AP1B1,TOMM40,AP3S1,RUFY1,TFRC,RAP1A,SNUPN,KPNA4,KPNA1,EIF4ENIF1,VPS26B,TIMM23,AP3S2,TIMM17A,RAB4A,TNPO2,AP1S1,TNPO3,AP2B1,KPNA2,CHMP7,AP2S1,VPS29,IPO4 |
| 3.998e-05 | -10.13 | GO_NUCLEAR_MATRIX | MSigDB lists | GO_NUCLEAR_MATRIX | 95 | 30 | 17377 | 2626 |
MBD1,NCOR2,DNMT3A,ATXN3,THOC1,PHB2,PSPC1,CXXC1,CENPF,ATXN1,GMCL1,MEN1,BLM,MATR3,LMNA,SMC3,AHCTF1,CLIC4,PSMA6,PPIG,AKAP8,PML,ZNF326,RUVBL2,RNASEL,YY1,OGG1,CFL1,HNRNPM,MORC3 |
| 4.006e-05 | -10.13 | CDC25A (cell division cycle 25A) | protein interactions | 993 | 85 | 29 | 17029 | 2761 |
GOPC,RAF1,SCYL1,E2F3,CUL3,CUL1,UBE4B,PKM,CCNB1,CSNK1A1,MAPK14,APP,CCDC28A,NPLOC4,RAD23A,CDK5,DNAJC10,CCNA2,WDR11,E2F4,E2F1,YWHAZ,CHEK2,ROCK1,MAP3K5,CDK2,E2F2,YWHAH,HRAS |
| 4.006e-05 | -10.13 | EIF2S2 (eukaryotic translation initiation factor 2 subunit beta) | protein interactions | 8894 | 85 | 29 | 17029 | 2761 |
EIF5A,CYLD,NCK1,CDC123,PRKDC,SUZ12,RPS10,RPL15,KIF23,CSNK2A1,EIF4G2,APP,RPA1,CAND1,RPA2,NSA2,PA2G4,SUB1,DDX56,UPF1,KLHL20,EXOSC1,H2AFX,PRMT7,FAU,FBL,RNF26,EIF5,CDC5L |
| 4.010e-05 | -10.12 | SARS (seryl-tRNA synthetase) | protein interactions | 6301 | 57 | 22 | 17029 | 2761 |
C9orf78,R3HCC1L,HARS,ARFIP2,SIRT2,MCM2,TARS,PAPOLA,NUP210,GATC,DUS3L,CCDC6,EFTUD2,UBA5,PPM1G,STAT1,ANP32E,PTGES3,ATP6V1C1,CDK2,TERF1,POT1 |
| 4.037e-05 | -10.12 | DEXDc | smart domains | SM00487 | 109 | 32 | 9493 | 1367 |
DDX58,RECQL,DDX47,SHPRH,YTHDC2,CHD1L,DHX9,SMARCA4,DHX8,BLM,CHD1,DDX56,EIF4A3,DDX31,DDX28,SNRNP200,DDX24,DHX29,BTAF1,DDX20,DDX39A,DHX57,DHX15,DDX17,DDX23,RAD54B,DHX16,CHD3,DDX5,DDX42,POLQ,DDX52 |
| 4.044e-05 | -10.12 | Mitochondrial translation elongation | REACTOME pathways | R-HSA-5389840 | 88 | 30 | 10287 | 1696 |
MRPL9,MRPL42,MRPS2,MRPS15,MRPL39,MRPS26,MRPL12,MRPL43,TUFM,MRPS10,MRPL16,MRPS14,MRPL19,MRPL50,MRPL2,DAP3,MRPL55,CHCHD1,MRPL27,MRPL34,MRPS27,MRPL54,MRPL48,MRPL40,MRPL11,MRPL21,MRPL13,MRPL3,MRPL32,MRPL57 |
| 4.053e-05 | -10.11 | GSE5542_IFNG_VS_IFNA_AND_IFNG_TREATED_EPITHELIAL_CELLS_24H_UP | MSigDB lists | GSE5542_IFNG_VS_IFNA_AND_IFNG_TREATED_EPITHELIAL_CELLS_24H_UP | 180 | 48 | 17377 | 2626 |
SKA3,NSMCE4A,MAX,ZNF445,TMBIM4,ZNF768,RAF1,PDAP1,TCF3,RBM8A,SDC2,SDHA,NDUFS4,LYAR,VASP,CCNA2,STRBP,RABGAP1L,ZBTB22,SPTSSA,CITED2,PHKG2,ELOF1,ABCC5,CSNK1G2,TIMP2,TACC1,AKT2,SELPLG,AURKB,SRSF5,TAZ,CCT8,TRIM28,MAT2A,RHBDF2,GLOD4,KIF2A,PWWP2B,MID1IP1,POLE,CORO1C,SAFB,TFDP1,STAT1,C4orf46,CD81,TSTD2 |
| 4.053e-05 | -10.11 | GSE22935_WT_VS_MYD88_KO_MACROPHAGE_24H_MBOVIS_BCG_STIM_UP | MSigDB lists | GSE22935_WT_VS_MYD88_KO_MACROPHAGE_24H_MBOVIS_BCG_STIM_UP | 180 | 48 | 17377 | 2626 |
SLC30A9,LZTR1,LIME1,CKLF,SHPRH,SCYL1,TRIO,BRAP,RRAGC,ARFIP2,NDUFA4,NENF,HCFC1R1,RGS2,PARK7,RPL11,WRNIP1,RNF121,PELO,YBX1,METTL9,SPTSSA,ASB6,DCTN1,NOL12,SEC61B,RPL38,LACTB,DNAJC9,BMS1,PRKRA,MCM2,MPG,GFER,RPA1,RPL36,KIF2A,TPD52L2,PDCD6,NIP7,RAB24,NDUFA11,OAZ2,FTSJ1,ZFP90,KPNA2,B4GALT3,SSRP1 |
| 4.053e-05 | -10.11 | GSE22611_NOD2_VS_CTRL_TRANSDUCED_HEK293T_CELL_UP | MSigDB lists | GSE22611_NOD2_VS_CTRL_TRANSDUCED_HEK293T_CELL_UP | 180 | 48 | 17377 | 2626 |
ANKRD27,LZTR1,GMFG,GNPDA1,RACGAP1,NIT2,CLCC1,EXT2,MAN1A1,MBD4,SEC11A,RFWD3,ATP13A3,KIF22,TTC3,RP2,CDC25B,MRPL40,ACAD8,SLC35C2,EIF5,CNPY3,TMX1,HNRNPM,KDM3B,EIF5A,RPS24,RTF1,BMS1,GALNT7,TMEM147,MBD3,ZDHHC3,BSDC1,UTP20,ZNF282,MKNK1,CSK,SETD3,RNF38,MPV17,MIA2,KPNA2,SRSF3,MRPL13,BRD9,USP13,EGLN1 |
| 4.053e-05 | -10.11 | GSE13485_DAY3_VS_DAY21_YF17D_VACCINE_PBMC_UP | MSigDB lists | GSE13485_DAY3_VS_DAY21_YF17D_VACCINE_PBMC_UP | 180 | 48 | 17377 | 2626 |
NCOR2,ZBTB10,CORO7,PARP12,BRAP,AGPAT3,EIF2AK4,SNN,TFRC,CAPN2,TET3,CCNK,NAPG,TNS3,ATP2A2,SAR1A,RIMS3,AKAP8,ETV6,SRSF4,ZNF746,CLCN6,FNIP2,RNF169,TRIM8,TNFAIP3,LAP3,PGS1,ATP2C1,KIAA0930,UHRF1BP1,MEF2D,HAUS8,MASTL,MAN2A2,SEC31A,MKNK1,PWWP2B,SCARB2,ZNF317,SPATA2,TFE3,PML,CCDC69,ZDHHC7,PITPNA,RGL1,ZMIZ1 |
| 4.053e-05 | -10.11 | GSE20484_MCSG_VS_CXCL4_MONOCYTE_DERIVED_MACROPHAGE_DN | MSigDB lists | GSE20484_MCSG_VS_CXCL4_MONOCYTE_DERIVED_MACROPHAGE_DN | 180 | 48 | 17377 | 2626 |
ABCA3,MPHOSPH8,KIAA0100,ZCCHC8,UBN1,CTCF,CDK13,PSEN1,RLF,PIP4K2A,CMTM6,ARL6IP6,UBXN2A,SNRNP25,SUB1,SRI,DAPK1,TXLNA,ORAI1,SS18L1,AFF1,RNF169,ADCY7,VPS13B,ACSL5,GCC2,SNRNP200,BTAF1,RFFL,NLN,LNX2,NFATC2,ARHGEF12,DCLRE1C,OTUD3,NECAP2,EIF4ENIF1,HSPB11,TBC1D17,AHNAK,JAK1,HNRNPR,CERS6,DCK,FN3KRP,MBD6,C7orf26,RNF114 |
| 4.053e-05 | -10.11 | GSE1740_MCSF_VS_MCSF_AND_IFNG_DAY2_DERIVED_MACROPHAGE_DN | MSigDB lists | GSE1740_MCSF_VS_MCSF_AND_IFNG_DAY2_DERIVED_MACROPHAGE_DN | 180 | 48 | 17377 | 2626 |
BCL2L12,MZT1,CDC40,NDUFS1,MPHOSPH8,ALKBH5,ASAH1,ATG2B,PRKACA,KIAA1147,MEX3C,DNAAF2,RAD23B,RAB4A,TPST1,SLC27A4,NFU1,FAM76B,ACAD8,TMEM8A,CNOT6L,LPCAT1,TMEM14C,CDKN2AIP,PPP3CA,ZMYND11,ZBED5,JTB,CIRBP,FBXO9,TMEM147,SEPT7,CDC23,H2AFV,EML4,RDH11,VPS26B,CCDC14,KLHL15,QARS,RWDD4,DTX4,DCAF11,MEGF9,MAPK1,CD81,CHPF2,HDAC2 |
| 4.053e-05 | -10.11 | GSE3982_CTRL_VS_PMA_STIM_EOSINOPHIL_UP | MSigDB lists | GSE3982_CTRL_VS_PMA_STIM_EOSINOPHIL_UP | 180 | 48 | 17377 | 2626 |
RAB14,RECQL,ANKH,CENPF,C5orf30,COX4I1,SNRPD3,TWF2,ASXL2,CRLF3,EXT2,APP,COPB2,MAN1A1,GNS,FAM192A,ANKRD26,FLAD1,VAV1,MZT2A,SRI,POLR1B,TALDO1,SLC35C2,ILKAP,NCOA2,RNF5,KDELR1,CYFIP1,CLCN3,PRKDC,SLC26A6,KIF15,RCOR1,STYXL1,PICALM,ZNF174,ANKRD46,ZFR,MYO1F,PSMD3,CEP55,DBI,HMGB2,MRFAP1L1,SPCS3,CHPT1,FAM208A |
| 4.053e-05 | -10.11 | GSE20754_WT_VS_TCF1_KO_MEMORY_CD8_TCELL_DN | MSigDB lists | GSE20754_WT_VS_TCF1_KO_MEMORY_CD8_TCELL_DN | 180 | 48 | 17377 | 2626 |
CYLD,HJURP,CLSPN,CDT1,HNRNPUL2,MOGS,MXD4,BLM,ANKRD28,MAT2B,PCNA,NUP210,PTEN,ATG3,MCM5,RABGAP1L,MEGF8,PPCDC,PDS5B,PRC1,TTC3,CISD2,TRIM14,EBAG9,PDLIM2,ENPP4,PPP3CA,ELOVL5,EID1,ASPM,NOA1,ZNF512,DCAF8,CPOX,RRM2,AURKB,ZDHHC3,CYB5A,GINS4,ATAD2,WDR11,CDCA5,WDR7,C4orf46,ACAT1,BRWD3,CD81,POT1 |
| 4.059e-05 | -10.11 | Fc receptor signaling pathway | biological process | GO:0038093 | 184 | 49 | 17256 | 2622 |
WASF2,RAC1,ACTR3,VAV2,CUL1,PPP3CB,NCKAP1,LYN,PSMD9,VAV1,PSMD2,NFATC3,PSMA6,PSMD1,SHC1,CDC42,ARPC5,PIK3R2,ABI1,PDPK1,CYFIP1,PPP3CA,NRAS,NCK1,PSMA8,PSMB7,PSMA1,WIPF1,NFATC2,UBE2V1,KRAS,CYFIP2,ARPC1A,PSMB9,PSMB3,PSMC4,MAPK3,WAS,ELMO1,TAB2,RPS27A,PSMD8,LIMK1,PSMD3,PPP3R1,ACTB,MAPK1,HRAS,PSMC1 |
| 4.067e-05 | -10.11 | regulation of autophagosome assembly | biological process | GO:2000785 | 37 | 16 | 17256 | 2622 |
TBC1D12,FEZ2,PHF23,PIP4K2C,UBQLN2,BECN1,PIP4K2A,SH3GLB1,MTMR3,CHMP4A,RALB,TBC1D14,CHMP4B,PIKFYVE,LRSAM1,RNF5 |
| 4.067e-05 | -10.11 | maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) | biological process | GO:0000462 | 37 | 16 | 17256 | 2622 |
KRI1,UTP20,UTP25,UTP18,TBL3,RPS14,RPS24,BMS1,UTP3,RRS1,PDCD11,TSR2,RRP36,BYSL,RPSA,KRR1 |
| 4.071e-05 | -10.11 | GINESTIER_BREAST_CANCER_ZNF217_AMPLIFIED_UP | MSigDB lists | GINESTIER_BREAST_CANCER_ZNF217_AMPLIFIED_UP | 69 | 24 | 17377 | 2626 |
PWWP2A,SRSF11,ADD1,POLK,SF3B1,MUM1,CYP20A1,LACTB,KCTD20,SLC17A5,CSNK1A1,STX16,SLC25A36,CDC42,KLHL20,SIAH1,RAD23B,BBX,APOOL,CREB1,F2R,N4BP2,SNX14,SRSF10 |
| 4.073e-05 | -10.11 | V$ZF5_01 | MSigDB lists | V$ZF5_01 | 225 | 57 | 17377 | 2626 |
RHOG,MAX,PLXNC1,PHF23,ADO,SUMO2,KLF13,CTCF,RRAGC,TM9SF3,KIF2C,USP48,FKBP2,ZADH2,RLF,STMN1,PABPC4,PHC2,PA2G4,KDM2A,UTP18,RAB35,FUT8,DNM2,TNPO2,SPTSSA,ST8SIA2,SENP1,ARID4A,TRIM8,ATP13A1,APH1A,DRAP1,PPIE,ARHGEF12,UBE4B,NUTF2,GFER,PICALM,EIF3A,DDX23,UBTF,NSF,VPS26B,CORO1C,TPP2,GADD45B,ATXN2L,BCL7C,UQCRH,ST3GAL2,RBBP4,NR2F2,LRP8,SLC25A33,B4GALT2,SMARCD1 |
| 4.095e-05 | -10.10 | RNA helicase activity | molecular function | GO:0003724 | 68 | 24 | 17224 | 2647 |
DDX28,DDX47,SNRNP200,DDX24,DHX29,HELB,YTHDC2,DHX9,DHX8,DDX20,DDX39A,DHX15,DHX57,RAD54B,DDX23,DDX17,DDX56,UPF1,EIF4A3,DHX16,DDX31,DDX5,DDX42,DDX52 |
| 4.096e-05 | -10.10 | GSE2585_AIRE_KO_VS_WT_CD80_HIGH_MTEC_DN | MSigDB lists | GSE2585_AIRE_KO_VS_WT_CD80_HIGH_MTEC_DN | 185 | 49 | 17377 | 2626 |
WSB2,ANKH,DCTN2,RGS2,MIEN1,APH1B,PCBP1,COPG2,MYL6B,SRXN1,FARSA,CLIC4,TBC1D22A,ATG3,IL6ST,MECR,PDCD2,MVP,PACS2,S100A6,MED22,JMJD4,NIPAL3,METTL1,USO1,RHOBTB3,GALC,AACS,NSDHL,RAB7A,SEPT8,EMP3,KRAS,CADM1,SLC17A5,AMDHD2,KLF6,MBD3,INF2,STT3A,NAGLU,CTSA,RGL1,SCARB1,WDR91,CHMP7,HRAS,RAB3IL1,ESYT2 |
| 4.096e-05 | -10.10 | GSE17186_MEMORY_VS_CD21LOW_TRANSITIONAL_BCELL_UP | MSigDB lists | GSE17186_MEMORY_VS_CD21LOW_TRANSITIONAL_BCELL_UP | 185 | 49 | 17377 | 2626 |
CTDP1,PTMS,ZNF496,PDCD6IP,COPA,MRPL42,DAP,MOGS,FLOT1,SUMF1,B4GALT4,PSEN1,SYNRG,GNB2,PIP4K2A,SPAG5,DPYSL2,MEGF8,MSH2,FAM89B,FOXN2,KIFAP3,PACS2,IMPA2,S100A6,WDR41,ENPP4,LARS,PSMA8,EID1,ATG9A,RAB7A,VDAC2,CKAP2L,BICD2,ANLN,PSMB9,IDE,PALB2,SURF4,MAGT1,CERS6,MYO18A,MBOAT1,CHEK2,HEXA,ESPL1,TUBB,STARD3NL |
| 4.096e-05 | -10.10 | GSE14308_TH17_VS_NAIVE_CD4_TCELL_UP | MSigDB lists | GSE14308_TH17_VS_NAIVE_CD4_TCELL_UP | 185 | 49 | 17377 | 2626 |
PDCD6IP,GMFG,HJURP,GNPNAT1,RRAGC,PXMP2,NENF,CPNE3,KIAA1147,UCHL5,KIF14,AP2B1,RPN2,KIFAP3,ALDH18A1,PPP6R1,IFT46,HTRA2,MYO5A,SRSF10,TSHZ1,FYTTD1,MND1,SEPT9,NSDHL,LRBA,CRNKL1,PSMA1,CCDC34,ANLN,GINS4,SRSF1,TPD52L2,PWWP2B,FNTA,POLE,MRPL55,RAD18,ORMDL2,PML,PKD2,MDH1,NDE1,CHMP7,C11orf1,EYA2,GCSH,RAD51D,SSRP1 |
| 4.096e-05 | -10.10 | GSE11924_TFH_VS_TH17_CD4_TCELL_UP | MSigDB lists | GSE11924_TFH_VS_TH17_CD4_TCELL_UP | 185 | 49 | 17377 | 2626 |
CCDC93,GCLM,GPR132,H2AFZ,SYS1,FAM53C,WDTC1,AGPAT1,EPN1,PCSK7,KLC1,CTCF,FAM8A1,ZER1,CYHR1,TBC1D22A,PPIL2,PTPN11,CLCN6,AFF1,ZC3H3,ARID4A,SPSB3,HP1BP3,ORAI2,GCC2,RHOA,BRD4,MAPRE2,DDX24,PPP1R21,MAN1B1,ILF3,WIPF1,PBRM1,MEF2D,SEPT7,POLG2,RAB22A,RPA1,BRWD1,FAM110A,PARG,RNASEL,WDR62,AP2S1,CABLES1,CBX4,SNAPIN |
| 4.096e-05 | -10.10 | GSE27786_LIN_NEG_VS_MONO_MAC_UP | MSigDB lists | GSE27786_LIN_NEG_VS_MONO_MAC_UP | 185 | 49 | 17377 | 2626 |
TCF12,UQCR10,HMGN3,SLC29A1,AP1B1,IFT27,ARID1B,HMG20A,GOLM1,FARSA,PSMD2,ZBTB45,STRBP,EI24,ECD,STRAP,RPL22L1,NIPSNAP1,PRPF19,GINS1,POU2AF1,TELO2,TDP1,GTF3C6,FAM172A,LAP3,NSDHL,TEX10,LRBA,TBRG4,SEPT8,BCLAF1,THNSL1,FXR1,BORA,MAT2A,XRCC5,UTP20,MRPL2,DAP3,POLE,EIF2D,PIAS2,IARS2,WIPI2,MAPK1,HRAS,SMARCD1,PTOV1 |
| 4.096e-05 | -10.10 | GSE10094_LCMV_VS_LISTERIA_IND_EFF_CD4_TCELL_UP | MSigDB lists | GSE10094_LCMV_VS_LISTERIA_IND_EFF_CD4_TCELL_UP | 185 | 49 | 17377 | 2626 |
RAB14,FEZ2,MRPS2,SHPRH,PPP1R15B,ANKH,TOR1AIP1,HABP4,TM9SF3,DOCK11,DCUN1D4,ZADH2,SYNRG,FAM8A1,WDR48,C2orf68,FKBP1A,ANKLE1,NRF1,SEC24C,DCP1A,NAP1L4,CREB1,TMEM8A,CGGBP1,MORC3,HP1BP3,RBM15B,NIPAL3,POLK,BTAF1,JTB,MRPL16,BMS1,NFATC2IP,TOLLIP,PSMB9,APPL1,CYB5A,MAN2A2,KPNA1,BRWD1,DGCR8,STK38,OGT,ZDHHC7,CNOT6,HEXA,NUMB |
| 4.096e-05 | -10.10 | GSE17721_LPS_VS_PAM3CSK4_1H_BMDC_UP | MSigDB lists | GSE17721_LPS_VS_PAM3CSK4_1H_BMDC_UP | 185 | 49 | 17377 | 2626 |
NAT9,PIGN,SARNP,GOLPH3L,MPHOSPH8,NDUFB6,FLYWCH2,GPR89A,PMS2,TMED3,LACTB2,CHAC2,COMMD5,TWF2,MRPL19,ARL6IP6,EBP,ABHD16A,ERH,MED8,KLHL20,RNFT1,DUT,BDH1,XPA,HADHB,AKR1B1,ACAD8,RBM15,SEH1L,PDPK1,BAK1,EID1,GABPA,NSDHL,NQO2,MRPL43,MAK16,SERP1,FKBP3,CBX3,SOCS7,SERF2,MFAP1,QARS,FTSJ1,COPS6,BRWD3,GPR89B |
| 4.096e-05 | -10.10 | GSE14308_TH1_VS_TH17_UP | MSigDB lists | GSE14308_TH1_VS_TH17_UP | 185 | 49 | 17377 | 2626 |
PKP4,EWSR1,MRPL42,CKLF,RWDD1,C1orf112,TMEM41B,NUP54,KIF23,KIF2C,CNTROB,DUSP22,STMN1,TMEM165,KIFC1,CAPN2,CENPJ,KIF14,POP7,LRRC59,TRIM14,ACSL5,CYFIP1,ERMP1,PRIM2,NEK7,IDH3A,SELPLG,MRS2,CDC6,BUD13,PDE3B,ASF1B,MTMR3,NAP1L1,MAPK6,STAT1,TBPL1,H2AFX,COX5A,FAM126A,GALNT10,NAA20,RRS1,ZMIZ1,E2F2,ZBTB11,UBE2C,NIPA1 |
| 4.096e-05 | -10.10 | GSE16385_MONOCYTE_VS_12H_IL4_TREATED_MACROPHAGE_DN | MSigDB lists | GSE16385_MONOCYTE_VS_12H_IL4_TREATED_MACROPHAGE_DN | 185 | 49 | 17377 | 2626 |
PPP1R37,CDS2,NUP188,PHRF1,RAF1,TRIM11,STRN4,ACAP1,FLOT1,UBE2Q1,SIRT2,AKT1S1,SNAPC4,GNB2,MDM2,HDAC7,RAB35,MTA1,PELO,PPP1R12C,AP2B1,ABCD1,PCYT2,CORO1A,LRSAM1,FGFR1OP2,DNAL4,PDLIM2,NIPAL3,MND1,CYTH1,TMEM39A,TUFM,UBE4B,UTP3,WBP1,ARID1A,ZNF777,GPS2,TATDN2,FASTK,PQBP1,ATXN2L,CTSA,NCLN,CENPT,SNRNP70,USP11,DDB1 |
| 4.096e-05 | -10.10 | GSE15733_BM_VS_SPLEEN_MEMORY_CD4_TCELL_DN | MSigDB lists | GSE15733_BM_VS_SPLEEN_MEMORY_CD4_TCELL_DN | 185 | 49 | 17377 | 2626 |
WASF2,CYTIP,SLC41A1,ZFP91,DYNLL1,PTTG1,ARID5A,ARID1B,GIT2,PIP4K2A,PNO1,ABL2,DECR1,PSMA6,IL6ST,ATIC,DDA1,AXIN2,MRPL40,RNF19A,TMEM160,POU2AF1,CYTH1,AATF,TEX10,METTL5,ITM2A,TOR1AIP2,SLC25A22,KRAS,NUTF2,VKORC1,TWISTNB,CLNS1A,ANKRD46,SH3BP5,KPNA4,HSPB11,KPNA1,CCDC86,PDLIM1,DCK,PSMD8,YWHAZ,RBBP4,SLC25A39,SMAD4,IPO4,TMEM131 |
| 4.127e-05 | -10.10 | GSE19923_WT_VS_HEB_AND_E2A_KO_DP_THYMOCYTE_DN | MSigDB lists | GSE19923_WT_VS_HEB_AND_E2A_KO_DP_THYMOCYTE_DN | 190 | 50 | 17377 | 2626 |
MBD1,IER2,KIAA0100,SLC41A1,PPP1R15B,SLC2A1,UBE2Z,JMJD6,DNAJB1,BIRC2,DNAJB9,CFLAR,PHC2,MED10,RNFT1,MDFIC,ALDH18A1,CITED2,TIPARP,F2R,PLK3,YTHDC1,ERF,BTG2,TOR1AIP2,SRSF5,WBP1,ANLN,ZFAND5,KLF6,TARS,RHOB,RBM38,MAT2A,AMZ2,MKNK1,SEC23IP,ETS2,CLK3,MAFK,MAPK6,NFIL3,U2SURP,H2AFX,RRS1,PGAM1,MZT2B,CAPN1,CSNK1D,SMARCD1 |
| 4.144e-05 | -10.09 | regulation of cell cycle G1/S phase transition | biological process | GO:1902806 | 194 | 51 | 17256 | 2622 |
UBE2E2,KMT2E,PHB2,CDK2AP2,CCNB1,CNOT11,PAGR1,CDC73,CNOT3,DDRGK1,RFWD3,CDKN2C,RPA2,RB1,PCNA,MDM2,PTEN,CENPJ,KIF14,FBXO7,GTSE1,CDKN1B,BRD7,BCL2,ECD,CNOT6L,CTDSP2,CARM1,PLK3,ADAM17,BTG2,PRKDC,CDC6,MEN1,SOX4,PRMT2,CNOT9,PAF1,RBL1,RPS27A,E2F4,TFDP1,E2F1,PML,FAM83D,CNOT6,PKD2,CHEK2,TFDP2,CDK2,CDKN2A |
| 4.147e-05 | -10.09 | SHEPARD_BMYB_MORPHOLINO_DN | MSigDB lists | SHEPARD_BMYB_MORPHOLINO_DN | 195 | 51 | 17377 | 2626 |
POU3F2,CHERP,FOXM1,DAP,TPX2,CDCA3,KIF23,SLC4A2,NOTCH2,CCNB1,RGS2,MIEN1,FBXO5,RTKN,HNRNPA2B1,MCM5,DUT,KIF14,PRC1,MSH2,GTSE1,CENPM,TOP1MT,DNMT1,TACC3,GINS1,PHF20L1,TK1,GALC,ASPM,DRAP1,MKI67,CDC6,BMS1,CDCA2,AURKB,MCM2,ANLN,KIF11,PRIM1,MASTL,DDX17,ATP1A1,BIRC5,DCK,CDCA7L,OGT,WDR76,NDE1,CDK2,ACSF2 |
| 4.147e-05 | -10.09 | GSE39152_BRAIN_VS_SPLEEN_CD103_NEG_MEMORY_CD8_TCELL_UP | MSigDB lists | GSE39152_BRAIN_VS_SPLEEN_CD103_NEG_MEMORY_CD8_TCELL_UP | 195 | 51 | 17377 | 2626 |
UBL3,MAX,PPP1R15B,ANKH,TAP1,AGFG1,BCL2L1,BRIX1,STMN1,RUFY1,LYRM2,PTPN2,CAPN2,PRKD3,MDM2,CLIC4,NDUFA2,NVL,ZNF639,MBD2,TANK,ATP13A3,ANKRD13C,RBM3,CHTOP,MINPP1,EIF5,LPCAT1,FGFR1OP2,SAP30,RFC3,USO1,NRAS,TOR1AIP2,MAP4K3,UHRF1BP1,PLEC,AZI2,ODC1,RFC2,FAS,HLA-B,DAP3,PLAA,DCK,U2SURP,STAT1,LRPPRC,RBMS1,HDAC2,PFKP |
| 4.176e-05 | -10.08 | GSE3565_DUSP1_VS_WT_SPLENOCYTES_POST_LPS_INJECTION_UP | MSigDB lists | GSE3565_DUSP1_VS_WT_SPLENOCYTES_POST_LPS_INJECTION_UP | 151 | 42 | 17377 | 2626 |
SRM,RPS15,RPS2,FAM208B,GLUD1,CCNL2,SND1,RAPGEF6,RPL23A,PA2G4,TNFAIP8,THADA,RPL17,IL6ST,INTS1,ARHGEF1,PDS5B,AHCY,RPL19,CLDND1,TTLL12,FRMD8,CSNK1G3,RLIM,RPL29,BRD4,RPL8,RPS10,NUP155,NFATC2IP,EIF3H,TWISTNB,RPL36,TTC13,RPL32,CSNK1G1,PRPS2,RPLP1,AEN,RPS26,NMD3,IPO4 |
| 4.179e-05 | -10.08 | CAPZA2 (capping actin protein of muscle Z-line subunit alpha 2) | protein interactions | 830 | 249 | 65 | 17029 | 2761 |
ADD1,LUZP1,ACTR3,MYH9,CDIPT,TWF2,SEC16A,DST,SH3BP1,RCSD1,CLTB,CARMIL1,STRAP,CFL1,DCTN1,PPP1R18,PSMG1,SMC2,OGDH,RAB1A,MCM2,ANLN,AFDN,TIMM13,AHNAK,CORO1C,MYO18A,CHMP4B,ARRB2,NUMB,PKP4,PPP1R12A,DCTN2,FLOT1,RACGAP1,CNOT11,MYL6B,CNOT3,ADD3,ARPC5,CAPZA1,DAPK1,GTSE1,NAP1L4,CNOT6L,GNAI2,MYO5A,CAMK2G,MICAL3,SPTAN1,PPP1R9B,WDR1,PLEC,PKM,MACF1,MARK2,PICALM,DAPK3,CNOT9,INF2,NAP1L1,ARAP1,LRPPRC,CNOT6,WDR76 |
| 4.190e-05 | -10.08 | Golgi stack | cellular component | GO:0005795 | 144 | 40 | 18223 | 2701 |
RAB14,GOLIM4,GOLPH3L,TMBIM4,B4GALT5,GPR89A,B4GALT1,TMED3,B4GALT4,BCAP31,RAB21,ASAP2,FUT8,NSFL1C,TMED2,LYPLA2,B3GALT6,PLK3,NAGPA,MOB4,USO1,TMEM115,APH1A,GOSR1,STX16,NUCB1,GALNT2,GOLGA7,GOLGA2,NSF,GOLGA8A,ARAP1,VCPIP1,CANT1,ST3GAL2,B4GALT3,CLN3,CHPF2,GPR89B,B4GALT2 |
| 4.195e-05 | -10.08 | ANKRD44 (ankyrin repeat domain 44) | protein interactions | 91526 | 22 | 12 | 17029 | 2761 |
ANKRD28,PLK1,CDKN2C,PPP6C,USP10,BRCA1,NOTCH2,PPP6R3,PPP6R2,MOB1A,PPP6R1,WWP2 |
| 4.199e-05 | -10.08 | EIF6 (eukaryotic translation initiation factor 6) | protein interactions | 3692 | 146 | 43 | 17029 | 2761 |
POLA2,BCCIP,PPIB,NOP2,RRP15,DHX9,CUL1,TOP2B,EBNA1BP2,AKT1S1,OAT,ABHD14A,BZW2,APP,TNFAIP8,RPL17,FBL,CFL1,PPAN,PLK1,TK1,RPL6,GTPBP4,CUL3,RPL8,RPS24,MCFD2,DDX39A,API5,ABCF1,CAND1,RPL36,CHMP4A,PFDN4,CHMP4B,ASNA1,FUS,RUVBL2,PPP5C,NMD3,CAPN1,IFI16,PDCD4 |
| 4.201e-05 | -10.08 | GO_REGULATION_OF_RESPONSE_TO_DNA_DAMAGE_STIMULUS | MSigDB lists | GO_REGULATION_OF_RESPONSE_TO_DNA_DAMAGE_STIMULUS | 132 | 38 | 17377 | 2626 |
MIF,BCL2L12,NSMCE4A,TRIP12,THOC1,FOXM1,EYA1,BABAM1,BCL2L1,TERF2IP,RFWD3,RPA2,MDM2,PCNA,AXIN2,FEM1B,OGG1,RNF169,TERF2,PGAP2,BRD4,RAD51AP1,HELB,BCLAF1,UBE2V1,MCL1,BRCA1,PTTG1IP,TRIM28,H2AFX,CEBPG,PML,DDX5,TRIM32,CLU,CHEK2,CDKN2A,POLQ |
| 4.219e-05 | -10.07 | GO_METHYLTRANSFERASE_COMPLEX | MSigDB lists | GO_METHYLTRANSFERASE_COMPLEX | 82 | 27 | 17377 | 2626 |
METTL1,MAX,CXXC1,SUZ12,SNRPB,TEX10,TRMT6,WDR82,EZH1,SNRPD3,WDR5,MEN1,METTL3,CLNS1A,ERH,STK38,METTL14,PRDM4,ZNF335,OGT,H2AFY,ACTB,RUVBL2,SNRPG,RBBP4,TAF6,HDAC2 |
| 4.219e-05 | -10.07 | GO_COATED_MEMBRANE | MSigDB lists | GO_COATED_MEMBRANE | 82 | 27 | 17377 | 2626 |
CHMP2A,TMED7,COPA,GGA1,SCYL1,COPE,AP3M2,TMED3,AP1B1,GGA2,AP4E1,AP3S1,SYNRG,COPG2,PICALM,COPB2,NECAP2,SEC31A,CHMP4A,AP3S2,SEC24C,AP1M1,AP1S1,AP2B1,CHMP4B,CLTB,AP2S1 |
| 4.228e-05 | -10.07 | BCAP31 (B cell receptor associated protein 31) | protein interactions | 10134 | 77 | 27 | 17029 | 2761 |
SEC61B,SCAMP3,RBM8A,VDAC2,OLA1,TMEM216,MYH9,COX4I1,BCL2L1,VKORC1,RAB1A,VDAC1,BCAP31,APP,HLA-A,CYB5A,RPA1,EVC2,DERL1,RPA2,SEC61A1,PGRMC1,BCAP29,BCL2,LMAN1,ATF2,RNF5 |
| 4.228e-05 | -10.07 | UQCRQ (ubiquinol-cytochrome c reductase complex III subunit VII) | protein interactions | 27089 | 77 | 27 | 17029 | 2761 |
IMMT,PDCD6IP,RAB7A,VDAC2,CYSTM1,LAMTOR3,NDUFA4,DNAJA1,ATP5MF,RAB1A,SDHA,SPPL2B,CDC73,HAUS2,OPTN,STOML2,ATP1A1,ATP2A2,DDOST,NDUFA2,COX7A2L,PML,ACAT1,UQCRH,NDUFS8,XRCC3,LMAN1 |
| 4.229e-05 | -10.07 | CARM1 (coactivator associated arginine methyltransferase 1) | protein interactions | 10498 | 115 | 36 | 17029 | 2761 |
CEP170B,HSPH1,UGP2,CUL1,SMARCA4,WDR5,XPO7,UBE2I,RAB11A,RBM4,IRF4,GTSE1,AFF1,CREB1,SMARCE1,PABPC1,NCOA2,TERF2,ATP6V1G1,CUL3,MTMR6,KRAS,MEF2D,ARID1A,BRCA1,CAND1,NECAP2,AXIN1,WDR4,ACTB,TICAM1,NCOA1,H3F3A,IFI16,FAF1,SMARCD1 |
| 4.253e-05 | -10.07 | response to nitrogen compound | biological process | GO:1901698 | 1005 | 198 | 17256 | 2622 |
MAX,AGRN,SIRT2,UBQLN2,MAPK14,BIRC2,RNF103,PRNP,EEF2K,CDK5,USF1,RAB8A,RAP1A,PCNA,GOT2,PIK3R2,SRSF4,DNM2,AKR1B1,UPRT,OGG1,DNMT1,CARM1,CDC5L,LARS,KLF10,GABPA,AKT2,GNG7,EZR,CDC6,LRP5,BRCA1,PRKRA,DHX15,HHEX,SMAD2,TMED10,OGT,ITGB1,PQBP1,ATP6V0C,ACTB,SMAD1,PSMC1,C2CD5,ATP6V0E1,HDAC2,SLC25A33,DDX58,TMUB1,AGTRAP,PRKAA1,DHX9,LAMTOR3,PSEN1,METTL3,ARID1B,SRRT,RHBDD1,NPLOC4,CFLAR,NDUFS4,RNF121,PDXP,EFTUD2,TIMELESS,ATP6V0A2,CYC1,GNAI2,ATP6V0D1,SOCS5,CYFIP1,AACS,ERLIN1,MAN1B1,UBE4B,SRSF5,SYVN1,ADRB2,PKM,MTR,APPL1,IRF5,PSMC4,ADSS,DERL1,CAT,EPRS,TSC1,CSK,NSMF,LAMTOR4,MAP3K5,RBBP4,CDK2,ECPAS,RNF139,EGLN1,TOMM20,ATXN3,DNMT3A,NQO1,UBR2,SLC2A1,WDTC1,RRAGC,IRF3,BCL2L1,ATP6V1B2,PRKACA,LYN,APP,GNB2,HNRNPA2B1,PDK2,ATP6V0B,MDM2,CCNA2,SHC1,RALB,ADCY9,CDKN1B,MAVS,AHCYL1,SPIDR,CFL1,ADCY7,ATP6V1G1,SEC61B,CGAS,KAT7,BTG2,SLC26A6,ATP6V0A1,ERBIN,EDEM2,SOCS7,ANKZF1,DNAJC10,IDE,SCAP,DGCR8,GUCY1B1,STAT6,SEL1L,STAT1,TICAM1,PPP5C,MAPK1,ABCA1,USP13,GCLM,CASP6,SRSF6,AGO2,FLOT1,UBE4A,SDF2L1,BLM,AP3S1,FOXO3,TUT4,DNAJB9,PTPN2,CAPN2,HOMER1,GRK2,PTEN,ARHGEF2,CREB1,STAT3,MYO5A,RNLS,RNF5,TGFB1,PDPK1,PPP1R9B,PPP3CA,RHOA,TNFAIP3,PRKDC,DENND4C,PRKAR1B,LDHA,RANGAP1,KCNQ1,MEN1,PDE3B,FADD,MAPK3,CACNB1,ATP6V1D,ZC3H7B,PKD2,ATP6V1C1,CD81,CPEB2 |
| 4.263e-05 | -10.06 | Antiviral mechanism by IFN-stimulated genes | REACTOME pathways | R-HSA-1169410 | 76 | 27 | 10287 | 1696 |
DDX58,NDC1,NUP188,RAE1,NUP54,NUP155,IRF3,EIF4G2,NUP205,ISG15,MAPK3,KPNA4,KPNA1,NUP210,JAK1,EIF4A3,RPS27A,PIN1,STAT1,NUP107,NUP62,NUP153,KPNA2,NUP85,NUP58,AAAS,SEH1L |
| 4.263e-05 | -10.06 | ISG15 antiviral mechanism | REACTOME pathways | R-HSA-1169408 | 76 | 27 | 10287 | 1696 |
DDX58,NDC1,NUP188,RAE1,NUP54,NUP155,IRF3,EIF4G2,NUP205,ISG15,MAPK3,KPNA4,KPNA1,NUP210,JAK1,EIF4A3,RPS27A,PIN1,STAT1,NUP107,NUP62,NUP153,KPNA2,NUP85,NUP58,AAAS,SEH1L |
| 4.263e-05 | -10.06 | GO_TUBULIN_BINDING | MSigDB lists | GO_TUBULIN_BINDING | 256 | 63 | 17377 | 2626 |
ZNF207,KIF3B,HSPH1,MAPRE1,RAE1,KIF23,B4GALT1,RACGAP1,SIRT2,KIF2C,RGS2,MAP1LC3B,STMN1,LYN,RAB11A,TUBGCP2,NEIL2,JAKMIP1,PRNP,KIFC1,DST,KIF5B,STARD9,DPYSL2,CENPJ,KIF14,KIF13B,PRC1,DNM2,ARHGEF2,KIF22,MAST2,OGG1,PLK1,PSRC1,MAPRE2,KIF15,CAMSAP1,TUBGCP5,EZR,NUSAP1,BRCA1,WDR81,MACF1,KIF11,PHF6,AKAP1,KRIT1,KIF2A,FNTA,KIF18A,GOLGA2,KIF18B,TTLL4,BIRC5,MAP4,LRPPRC,FAM83D,PPP5C,NDE1,REEP4,TERF1,RAD51D |
| 4.265e-05 | -10.06 | SIMBULAN_PARP1_TARGETS_DN | MSigDB lists | SIMBULAN_PARP1_TARGETS_DN | 17 | 10 | 17377 | 2626 |
PCNA,CCNA2,RANGAP1,HMGB2,TAGLN2,CCNB1,STMN1,CCNB2,DNMT1,PRIM1 |
| 4.270e-05 | -10.06 | WARS (tryptophanyl-tRNA synthetase) | protein interactions | 7453 | 65 | 24 | 17029 | 2761 |
CYLD,HARS,GNPDA1,MDH2,CDK2AP2,PSMG1,ADSL,RABIF,APP,KTN1,ISG15,SH3GLB1,USP5,RAD23A,NUCB1,PCNA,GART,DDA1,KPNA2,EHD4,TATDN1,CD81,NIPSNAP2,TERF1 |
| 4.270e-05 | -10.06 | GNL2 (G protein nucleolar 2) | protein interactions | 29889 | 65 | 24 | 17029 | 2761 |
NOL12,PPAN,NIFK,REPS2,ZNF512,MECP2,RPL8,GTPBP4,MPG,RBM4,APP,USP36,LMNA,RPL23A,CAND1,LYAR,NSA2,DDX56,DGCR8,RBM34,ZC3H3,ZC3HAV1,IFI16,GPATCH4 |
| 4.270e-05 | -10.06 | MRPL44 (mitochondrial ribosomal protein L44) | protein interactions | 65080 | 65 | 24 | 17029 | 2761 |
IMMT,MRPL9,CYLD,MRPL42,MRPL39,TCF3,MRPL12,MRPL43,ILF3,CUL3,KIF15,ATP6V0A1,USP22,EIF4H,MRPL19,MRPL50,SHC1,NDUFA11,MPV17,DUSP11,TARDBP,ARRB2,MRPL13,MRPL32 |
| 4.289e-05 | -10.06 | SSR4 (signal sequence receptor subunit 4) | protein interactions | 6748 | 73 | 26 | 17029 | 2761 |
COX15,CYLD,SUZ12,ILF3,CUL3,COX4I1,NENF,ADRB2,SNRPD3,MCM2,VDAC1,MAD2L2,RPSA,SSR1,CAND1,RPN1,DDOST,MAGT1,PTEN,HUWE1,NCLN,RPN2,ATP5F1A,TECR,CLN3,CDK2 |
| 4.289e-05 | -10.06 | AHCY (adenosylhomocysteinase) | protein interactions | 191 | 73 | 26 | 17029 | 2761 |
EWSR1,FOXK1,CUL3,XIAP,CUL1,BRCA1,MCM2,H2AFV,DHX15,EVC2,CAND1,DERL1,HLA-B,CEP104,HUWE1,ATIC,NSFL1C,AHCY,FUS,AHCYL1,CDK2,HEXA,ATF2,TERF1,POT1,LDHB |
| 4.289e-05 | -10.06 | CBX1 (chromobox 1) | protein interactions | 10951 | 73 | 26 | 17029 | 2761 |
DNMT3A,VHL,MECP2,CHD1L,PCGF6,MKI67,NFATC2,BRCA1,THRAP3,VDAC1,TRIM28,CHAF1A,CBX3,RB1,PCNA,SP100,KMT5C,SUV39H2,BANF1,H2AFY,AHDC1,H3F3A,DNMT1,ARL5A,IFI16,ADNP2 |
| 4.293e-05 | -10.06 | GNF2_RBBP6 | MSigDB lists | GNF2_RBBP6 | 65 | 23 | 17377 | 2626 |
SRP72,DDX47,SUZ12,BTAF1,EIF3D,NOL8,NACA,GTF3A,DCLRE1C,PAPOLA,NSA2,RBM25,NOL11,HNRNPH3,RBM34,RBMX,TARDBP,PIKFYVE,FBL,NGLY1,RBM15,CCDC59,ZNF146 |
| 4.293e-05 | -10.06 | REACTOME_APC_C_CDC20_MEDIATED_DEGRADATION_OF_MITOTIC_PROTEINS | MSigDB lists | REACTOME_APC_C_CDC20_MEDIATED_DEGRADATION_OF_MITOTIC_PROTEINS | 65 | 23 | 17377 | 2626 |
PSMA8,PTTG1,PSMB7,PSMA1,ANAPC2,CDC23,CCNB1,PSMD9,PSMB9,PSMB3,PSMC4,PSMD2,PSMA6,CDC16,PSMD1,CDC27,RPS27A,PSMD8,PSMD3,ANAPC7,UBE2C,PSMC1,ANAPC4 |
| 4.306e-05 | -10.05 | TIMM13 (translocase of inner mitochondrial membrane 13) | protein interactions | 26517 | 69 | 25 | 17029 | 2761 |
MIF,MOB4,CPNE1,TIMM8B,SF3B1,CDT1,CUL3,RNPS1,EZR,CUL1,CAPZA2,MATR3,SNRPA,CAND1,SF3B2,HNRNPA2B1,SEC23IP,BCL7C,CAB39,YWHAZ,XRCC3,WIPI2,ALDH18A1,MRPL3,TIMM50 |
| 4.326e-05 | -10.05 | HER-positive_carcinoma | COSMIC cancer mutations | HER-positive_carcinoma | 2055 | 367 | 17385 | 2587 |
FGFR1OP,ZBTB10,MAX,PNISR,TSC2,XIAP,USP39,MYEF2,FBXO22,EEF2K,NUP153,CDC25B,TFG,TIPARP,DNMT1,SENP1,FTSJ3,USP34,BAK1,ERCC1,NRAS,AKT2,PLEKHM3,USP22,AURKB,CCNF,SLC25A5,CBFB,TRIM47,WAS,SMAD2,RAD18,AXIN1,MAP4,ITGB1,OGT,TRAF5,ARRB2,ZNF598,HDAC2,EWSR1,CLSPN,KIAA0100,RHOC,HLA-E,VAV2,PRKAA1,RAB23,ACAP1,EIF2AK4,NOTCH2,APH1B,PSEN1,CDC73,VPS25,MEX3C,ZNRF2,ATIC,MSH2,GEMIN4,PIKFYVE,SOCS5,PHF10,GCC2,IFRD1,PRRC2A,DHX29,RPS10,MFNG,USP10,RIT1,ARID1A,ADRB2,ELK1,RHOB,FAS,XRCC5,PTPRF,MAGED2,ETS2,ERGIC3,PIAS2,USP32,VCPIP1,TCOF1,NDE1,MAP3K5,PPP6R3,CDK2,CABLES1,CDKN2A,CYTIP,ABCA3,SARNP,ATXN3,DNMT3A,REPS2,RAF1,SUZ12,UBR2,RAC1,BCL2L1,PRKACA,KTN1,REPS1,ANKIB1,DECR1,CCNA2,FBXL6,AHCTF1,SHC1,KDM2A,MTMR4,RALB,UCHL5,UBA5,ZCCHC2,SOCS6,MRPS27,CDKN1B,TTC3,RNF19A,RNASEH2A,RBM15,ATF2,ZC3H3,CDK12,SHOC2,BRD4,MKLN1,ERF,SLBP,ELP4,PKMYT1,MEF2D,ERC1,TRIM28,DDX17,PPP2CA,RAD51C,PPP2R5A,JAK1,STAT1,FUS,KLHDC4,GEN1,EYA2,POLQ,RHEBL1,PRPF4B,USP13,OTUD5,C1orf112,TCF3,BRAP,BLM,IL21R,ETS1,FOXO3,CCDC28A,MAD2L2,NEIL2,TMCC3,WWP2,RFWD3,CAPN2,PDCD10,HUWE1,PTEN,AXIN2,PTPN11,ANXA5,LTN1,UBE3B,CREB1,FBXL19,TPCN1,NCOA2,MSH6,PDPK1,ZFP64,TNFAIP3,KAT2A,COMMD4,KLF6,MARK2,PICALM,FADD,SH3BP5,KEAP1,POLE,CCDC6,ZHX1,WNT5B,MAPK6,CAPN7,PML,SLC25A19,PPP1R11,DUSP11,RGL1,PARP10,YWHAH,DDB1,NF1,GPBP1L1,TRIM11,FAM129A,CSNK2A1,S1PR2,USP48,MAPK14,BIRC2,CUTC,SF3B2,MBD4,FANCL,ABL2,RAP1A,CDC42,ZNF639,JAZF1,PIK3R2,ETV6,XRCC2,JOSD1,TCEA1,OGG1,CARM1,CDC37,PLK1,CELSR2,SEPT9,NCK1,APH1A,VHL,RRM2,CDC6,LRP5,BRCA1,KMT2C,USP21,RHEB,DHX15,FBXO28,U2SURP,SOCS4,BAZ1B,STK11,DVL1,CHEK2,COPS6,NUMB,PARP12,LAMTOR3,PCSK7,MEF2A,THRAP3,RAPGEF6,NUP205,DTL,RB1,CCP110,XPA,CTR9,BCL2,MAML1,UBE3C,ZRANB1,N4BP2,TRAPPC9,CIC,NSDHL,AMD1,KRAS,GNAS,SDHB,TSC1,MBIP,ITPRIPL1,PCM1,CDC27,SYNCRIP,PALB2,ODF2,YWHAZ,NUP62,ADNP2,SMARCD1,TCF12,USP7,PRKAB1,CYLD,TRAF7,UGP2,COPE,PMS2,EXT2,CHD1,USP5,VAV1,MDM2,CD3EAP,ABI1,DVL2,POU2AF1,BIRC3,SLC26A6,GLO1,FANCE,EIF3H,USP36,ZNF700,RBL1,STK38,STAT6,UHRF2,DNAJC17,NCOA1,USP11,H3F3A,SMURF1,MAPK1,ABCA1,USP53,SMAD4,INTS2,SMAP1,TRIP12,CASP6,EYA1,SMC6,CHIC2,SUMF1,CSNK1A1,GFM2,FZD6,FBXO5,KIF5B,HERC3,FGFR3,IRF4,KLHL20,SS18L1,STAT3,GINS1,TGFB1,PHF20L1,ADAM17,HMGN1,RHOA,ARHGEF12,PCGF1,MEN1,TFEB,MAPK3,KPNA4,ATP6V1D,FBXO41,BIRC5,NEIL3,TFE3,BBX,DTX4,USP20,RBPJ,HRAS |
| 4.326e-05 | -10.05 | breast-carcinoma-HER-positive_carcinoma | COSMIC cancer mutations | breast-carcinoma-HER-positive_carcinoma | 2055 | 367 | 17385 | 2587 |
FGFR1OP,ZBTB10,MAX,PNISR,TSC2,XIAP,USP39,MYEF2,FBXO22,EEF2K,NUP153,CDC25B,TFG,TIPARP,DNMT1,SENP1,FTSJ3,USP34,BAK1,ERCC1,NRAS,AKT2,PLEKHM3,USP22,AURKB,CCNF,SLC25A5,CBFB,TRIM47,WAS,SMAD2,RAD18,AXIN1,MAP4,ITGB1,OGT,TRAF5,ARRB2,ZNF598,HDAC2,EWSR1,CLSPN,KIAA0100,RHOC,HLA-E,VAV2,PRKAA1,RAB23,ACAP1,EIF2AK4,NOTCH2,APH1B,PSEN1,CDC73,VPS25,MEX3C,ZNRF2,ATIC,MSH2,GEMIN4,PIKFYVE,SOCS5,PHF10,GCC2,IFRD1,PRRC2A,DHX29,RPS10,MFNG,USP10,RIT1,ARID1A,ADRB2,ELK1,RHOB,FAS,XRCC5,PTPRF,MAGED2,ETS2,ERGIC3,PIAS2,USP32,VCPIP1,TCOF1,NDE1,MAP3K5,PPP6R3,CDK2,CABLES1,CDKN2A,CYTIP,ABCA3,SARNP,ATXN3,DNMT3A,REPS2,RAF1,SUZ12,UBR2,RAC1,BCL2L1,PRKACA,KTN1,REPS1,ANKIB1,DECR1,CCNA2,FBXL6,AHCTF1,SHC1,KDM2A,MTMR4,RALB,UCHL5,UBA5,ZCCHC2,SOCS6,MRPS27,CDKN1B,TTC3,RNF19A,RNASEH2A,RBM15,ATF2,ZC3H3,CDK12,SHOC2,BRD4,MKLN1,ERF,SLBP,ELP4,PKMYT1,MEF2D,ERC1,TRIM28,DDX17,PPP2CA,RAD51C,PPP2R5A,JAK1,STAT1,FUS,KLHDC4,GEN1,EYA2,POLQ,RHEBL1,PRPF4B,USP13,OTUD5,C1orf112,TCF3,BRAP,BLM,IL21R,ETS1,FOXO3,CCDC28A,MAD2L2,NEIL2,TMCC3,WWP2,RFWD3,CAPN2,PDCD10,HUWE1,PTEN,AXIN2,PTPN11,ANXA5,LTN1,UBE3B,CREB1,FBXL19,TPCN1,NCOA2,MSH6,PDPK1,ZFP64,TNFAIP3,KAT2A,COMMD4,KLF6,MARK2,PICALM,FADD,SH3BP5,KEAP1,POLE,CCDC6,ZHX1,WNT5B,MAPK6,CAPN7,PML,SLC25A19,PPP1R11,DUSP11,RGL1,PARP10,YWHAH,DDB1,NF1,GPBP1L1,TRIM11,FAM129A,CSNK2A1,S1PR2,USP48,MAPK14,BIRC2,CUTC,SF3B2,MBD4,FANCL,ABL2,RAP1A,CDC42,ZNF639,JAZF1,PIK3R2,ETV6,XRCC2,JOSD1,TCEA1,OGG1,CARM1,CDC37,PLK1,CELSR2,SEPT9,NCK1,APH1A,VHL,RRM2,CDC6,LRP5,BRCA1,KMT2C,USP21,RHEB,DHX15,FBXO28,U2SURP,SOCS4,BAZ1B,STK11,DVL1,CHEK2,COPS6,NUMB,PARP12,LAMTOR3,PCSK7,MEF2A,THRAP3,RAPGEF6,NUP205,DTL,RB1,CCP110,XPA,CTR9,BCL2,MAML1,UBE3C,ZRANB1,N4BP2,TRAPPC9,CIC,NSDHL,AMD1,KRAS,GNAS,SDHB,TSC1,MBIP,ITPRIPL1,PCM1,CDC27,SYNCRIP,PALB2,ODF2,YWHAZ,NUP62,ADNP2,SMARCD1,TCF12,USP7,PRKAB1,CYLD,TRAF7,UGP2,COPE,PMS2,EXT2,CHD1,USP5,VAV1,MDM2,CD3EAP,ABI1,DVL2,POU2AF1,BIRC3,SLC26A6,GLO1,FANCE,EIF3H,USP36,ZNF700,RBL1,STK38,STAT6,UHRF2,DNAJC17,NCOA1,USP11,H3F3A,SMURF1,MAPK1,ABCA1,USP53,SMAD4,INTS2,SMAP1,TRIP12,CASP6,EYA1,SMC6,CHIC2,SUMF1,CSNK1A1,GFM2,FZD6,FBXO5,KIF5B,HERC3,FGFR3,IRF4,KLHL20,SS18L1,STAT3,GINS1,TGFB1,PHF20L1,ADAM17,HMGN1,RHOA,ARHGEF12,PCGF1,MEN1,TFEB,MAPK3,KPNA4,ATP6V1D,FBXO41,BIRC5,NEIL3,TFE3,BBX,DTX4,USP20,RBPJ,HRAS |
| 4.375e-05 | -10.04 | ACTH_non_functioning | COSMIC cancer mutations | ACTH_non_functioning | 9 | 7 | 17385 | 2587 |
CDKN2C,RB1,KRAS,NRAS,HRAS,AXIN1,CDKN2A |
| 4.375e-05 | -10.04 | central_nervous_system-medulla-glioma-astrocytoma_Grade_I | COSMIC cancer mutations | central_nervous_system-medulla-glioma-astrocytoma_Grade_I | 9 | 7 | 17385 | 2587 |
KRAS,NRAS,NF1,PTEN,HRAS,CDKN2A,PTPN11 |
| 4.425e-05 | -10.03 | GO_TRANSLATIONAL_TERMINATION | MSigDB lists | GO_TRANSLATIONAL_TERMINATION | 91 | 29 | 17377 | 2626 |
MRPL9,MRPL42,MRPS15,MRPL39,GSPT2,MRPL12,MRPL43,MRPS26,MRPS10,MRPL16,MRPS14,GFM2,MRPL19,MRPL50,MRPL2,DAP3,MRPL55,CHCHD1,MRPL27,MRPS27,MRPL34,MRPL54,MRPL40,MRPL48,MRPL11,MRPL21,MRPL13,MRPL3,MRPL32 |
| 4.439e-05 | -10.02 | DHX36 (DEAH-box helicase 36) | protein interactions | 170506 | 46 | 19 | 17029 | 2761 |
CCDC93,UNK,PRKAB1,IVNS1ABP,CUL3,SEPT7,RPA1,CAND1,RPA2,HINT1,RBMX,DDX5,TARDBP,TAGLN2,PTGES3,IFI16,BYSL,S100A6,FUBP1 |
| 4.439e-05 | -10.02 | LAGE3 (L antigen family member 3) | protein interactions | 8270 | 46 | 19 | 17029 | 2761 |
SEPHS2,PTMS,TP53RK,MCFD2,OGFR,NDRG3,RAB5B,RPSA,GINS4,USP5,CAND1,MAGED2,MCM5,RPAP1,CNN2,AHCYL1,SSSCA1,RNF114,USP34 |
| 4.439e-05 | -10.02 | Kifc1 (kinesin family member C1) | protein interactions | 100502766 | 46 | 19 | 17029 | 2761 |
PNISR,CHERP,SF3B1,RANGAP1,CDK11B,TFRC,KPNA4,DNAJC8,RBM25,HPS5,NUP107,ARHGEF2,NUP153,KPNA2,MRPL48,SEH1L,CCAR1,SMARCD1,DDX42 |
| 4.460e-05 | -10.02 | positive regulation of autophagy | biological process | GO:0010508 | 104 | 32 | 17256 | 2622 |
TSC2,SCOC,PRKAA1,EIF2AK4,BECN1,PIP4K2A,TRIM65,PARK7,EPM2A,RALB,FBXO7,DAPK1,LRSAM1,TPCN1,CDC37,PLK3,ATP5IF1,TRIM8,PIP4K2C,GBA,ADRB2,SH3GLB1,TFEB,MFN2,MAPK3,OPTN,TSC1,STK11,TICAM1,ROCK1,SMURF1,SVIP |
| 4.466e-05 | -10.02 | purine nucleotide metabolic process | biological process | GO:0006163 | 365 | 84 | 17256 | 2622 |
COX15,NDUFA5,PPCS,NDUFB6,UQCR10,OLA1,SLC35B2,EFL1,ADPGK,ATP6V1B2,ATP5PF,SDHA,IMPAD1,ADCY9,PPCDC,NDUFB9,SLC26A2,ADCY7,ATP6V0A1,OGDH,NDUFA7,NDUFB1,TAZ,STOML2,HINT1,GUCY1B1,NDUFA11,COX5A,DHTKD1,UQCRH,NUDT11,PFKP,NDUFV2,COX5B,GALK1,NDUFS1,MECP2,RAB23,NDUFA4,COX4I1,CYCS,ABHD14B,ATP5F1B,NDUFS7,NDUFS4,GART,NDUFV1,NDUFA2,NDUFB4,ATIC,MSH2,TPST1,ATP6V0A2,NDUFS8,CYC1,NDUFA3,AMPD2,TGFB1,RHOA,GUK1,NUDT4,LDHA,ADSL,ATP5MF,PKM,PDE3B,HSPA1B,ADSS,MBIP,ATP5MC3,PARG,PRPS2,COX7A2L,ACLY,COX8A,IMPDH1,ACAT1,DNPH1,NDUFS5,ATP5F1A,GPI,NIPSNAP2,PGAM1,NUDT3 |
| 4.490e-05 | -10.01 | MODULE_273 | MSigDB lists | MODULE_273 | 45 | 18 | 17377 | 2626 |
TXNL1,NDUFV2,POLR2I,POLR2G,ATP6V1B2,CBFB,NDUFS4,ATP6V0B,NDUFV1,STAT1,YBX1,NDUFS8,ATP6V0C,NDUFS5,BTF3,RBPJ,PPA1,ATP6V1G1 |
| 4.503e-05 | -10.01 | regulation of protein stability | biological process | GO:0031647 | 250 | 62 | 17256 | 2622 |
ZNF207,USP7,ZBED3,PPIB,PHB2,FLOT1,CREBL2,CDC73,PARK7,RAD23A,PRNP,RPL11,NAPG,PDCD10,MDM2,SIAH1,PTEN,PIN1,FBXO7,GTSE1,BCL2,PTGES3,CREB1,IFT46,RNF5,MORC3,CDC37,CHP1,PLK1,CCT2,CDKN2AIP,TELO2,KAT2A,VHL,PRKDC,GTPBP4,CUL3,KRAS,SYVN1,OTUD3,WDR81,SOX4,PRKRA,CCT8,USP36,SH3GLB1,HSPA1B,DERL1,TSC1,GOLGA7,SEL1L,QRSL1,NCLN,CTSA,CHEK2,CLU,DVL1,FBXL3,CD81,MAPK1,RNF139,USP13 |
| 4.518e-05 | -10.00 | sequence-specific single stranded DNA binding | molecular function | GO:0098847 | 14 | 9 | 17224 | 2647 |
TERF2IP,HNRNPA2B1,RPA2,NABP2,PCBP1,TERF1,POT1,RPA1,TERF2 |
| 4.518e-05 | -10.00 | GSE29617_CTRL_VS_TIV_FLU_VACCINE_PBMC_2008_UP | MSigDB lists | GSE29617_CTRL_VS_TIV_FLU_VACCINE_PBMC_2008_UP | 166 | 45 | 17377 | 2626 |
CYTIP,FAM208B,IVNS1ABP,GNE,ARID5A,IP6K2,RGS2,RGS1,ZNF92,DNAJB9,SAP130,SIAH1,AKAP8,SRSF4,ZNF326,ZFYVE27,DCP1A,TIPARP,SAMD4B,YTHDC1,PLK3,DDX24,ETV3,COQ10B,BTG2,KAT7,USP42,SREK1,BCLAF1,RANGAP1,MEF2D,RAB1A,EML4,DHX15,USP36,RAB18,GOLGA4,L3MBTL3,MAFK,KLHL15,ARNTL,SAMD8,BEND6,SMNDC1,DYNC1LI2 |
| 4.527e-05 | -10.00 | regulation of vacuole organization | biological process | GO:0044088 | 41 | 17 | 17256 | 2622 |
TBC1D12,FEZ2,PHF23,PIP4K2C,UBQLN2,BECN1,PIP4K2A,SH3GLB1,MTMR3,SCARB2,CHMP4A,RALB,TBC1D14,CHMP4B,PIKFYVE,LRSAM1,RNF5 |
| 4.531e-05 | -10.00 | Glutaminolysis and Cancer | SMPDB pathways | SMP02298 | 35 | 16 | 992 | 167 |
SDHB,SLC1A4,SUCLG1,GOT2,IDH3A,MDH2,ACLY,LDHA,CS,SLC16A1,SUCLG2,GLUD1,OGDH,IDH3B,SDHA,MPC1 |
| 4.542e-05 | -10.00 | POLR1C (RNA polymerase I and III subunit C) | protein interactions | 9533 | 111 | 35 | 17029 | 2761 |
NOP9,BCCIP,DDX47,FAM208B,POLR2K,EBNA1BP2,POLR3K,RRN3,CD3EAP,RTCB,CTPS1,RPAP1,CORO1A,POLR1B,CFL1,RPAP3,DDX24,POLR2L,ABCF2,GTPBP4,CUL3,PSMB7,CIRBP,POLR3GL,NFATC2,GAR1,TWISTNB,MBIP,POLR2J,CRCP,CLU,USP11,ARRB2,NMD3,BYSL |
| 4.586e-05 | -9.99 | GO_MICROTUBULE_ORGANIZING_CENTER_ORGANIZATION | MSigDB lists | GO_MICROTUBULE_ORGANIZING_CENTER_ORGANIZATION | 78 | 26 | 17377 | 2626 |
PLK1,KIF3B,GCC2,PPP1R12A,TUBGCP5,HAUS4,WDR81,BRCA1,CNTROB,KIF11,HAUS2,TUBGCP2,HAUS8,PCM1,CCP110,GOLGA2,CHD3,CENPJ,XRCC2,SLC16A1,PKD2,CEP63,WDR62,NDE1,SASS6,CDK2 |
| 4.586e-05 | -9.99 | SAKAI_CHRONIC_HEPATITIS_VS_LIVER_CANCER_UP | MSigDB lists | SAKAI_CHRONIC_HEPATITIS_VS_LIVER_CANCER_UP | 78 | 26 | 17377 | 2626 |
UBE2D3,USP7,TXN,ST13,NCK1,TACC1,LAMTOR3,CUL1,SRSF1,FBXO5,CBX3,CAT,KPNA4,PCNA,HSPA4,CTSS,JAK1,HNRNPR,PRDX3,AXIN2,PPP3R1,ATF6,MAP3K5,ATF2,ESPL1,SMNDC1 |
| 4.586e-05 | -9.99 | GNF2_STAT6 | MSigDB lists | GNF2_STAT6 | 78 | 26 | 17377 | 2626 |
TGFB1,CORO7,HLA-E,ACTR3,EMP3,ARHGDIB,ADPGK,DAZAP2,LYN,GIT2,SERP1,CMTM6,HLA-A,SEC11A,VAV1,HLA-B,WAS,ARPC5,SNAP23,MBD2,STAT6,CAPZA1,OSTF1,CORO1A,MOB1A,ANXA11 |
| 4.600e-05 | -9.99 | GSE6259_33D1_POS_VS_DEC205_POS_FLT3L_INDUCED_SPLENIC_DC_DN | MSigDB lists | GSE6259_33D1_POS_VS_DEC205_POS_FLT3L_INDUCED_SPLENIC_DC_DN | 171 | 46 | 17377 | 2626 |
NCOR2,CYLD,TOR3A,MAGED1,RRM1,SLC29A1,PPP3CB,LANCL1,UBQLN2,GGA2,ELMOD2,EXT2,IL6ST,ABCD1,MAVS,CYB5R1,SLC35C2,CLN6,RNLS,NIPSNAP1,ANKLE2,GALC,NEK7,NSDHL,OXR1,SLC16A7,SCFD2,ATXN1,NFATC2,TMEM147,NDRG3,HHEX,SCARB2,TMEM41A,IDE,GALNT2,CHD3,LIMK1,STAT1,ASNA1,ATF6,MDH1,RNASEL,WDR62,AAAS,TMEM131 |
| 4.609e-05 | -9.99 | GNF2_CD53 | MSigDB lists | GNF2_CD53 | 57 | 21 | 17377 | 2626 |
CYTIP,CORO7,RPS6KA1,HLA-E,ACTR3,TAP1,MFNG,WIPF1,ARHGDIB,PSMB9,CRLF3,GIT2,HLA-A,VAV1,HLA-B,WAS,CSK,STAT6,OSTF1,CORO1A,IFI16 |
| 4.609e-05 | -9.99 | PEART_HDAC_PROLIFERATION_CLUSTER_UP | MSigDB lists | PEART_HDAC_PROLIFERATION_CLUSTER_UP | 57 | 21 | 17377 | 2626 |
MAPRE2,KLF10,CREG1,BTG2,SEPT8,CDC6,SIRT2,KIF2C,ANLN,CCNF,BLM,MXD1,PRDX1,TPD52L2,RAP1A,MLX,KPNA2,CDK2,TOB1,CDC37,DCTN1 |
| 4.609e-05 | -9.98 | GO_POSITIVE_REGULATION_OF_CHROMOSOME_ORGANIZATION | MSigDB lists | GO_POSITIVE_REGULATION_OF_CHROMOSOME_ORGANIZATION | 142 | 40 | 17377 | 2626 |
GORASP1,CCNB1,BECN1,FBXO5,RB1,PTEN,AKAP8,BRD7,H2AFY,CTR9,CHTOP,DNMT1,TERF2,TGFB1,PLK1,ERCC1,CCT2,KAT2A,NEK7,MIER1,WBP2,CUL3,RTF1,BRCA1,AURKB,RAB1A,CCT8,TRIM28,MAPK3,MAP3K4,PAF1,GOLGA2,NSMCE2,PML,OGT,RUVBL2,MAPK1,SMAD4,POT1,ESPL1 |
| 4.666e-05 | -9.97 | GSE12366_GC_VS_MEMORY_BCELL_UP | MSigDB lists | GSE12366_GC_VS_MEMORY_BCELL_UP | 176 | 47 | 17377 | 2626 |
TMEM106C,MAPRE1,MCM10,CENPF,TPX2,SPAG5,RBM17,SAP130,DTL,CLIC4,KLHL5,ATP2A2,TIMELESS,H2AFY,FAM76B,CENPM,C12orf75,DNMT1,STRAP,GINS1,POU2AF1,TK1,PSRC1,TACC1,NET1,PBK,MAP4K4,E2F3,CDCA2,MCM2,ASB13,SLC25A5,ODC1,EIF4H,DHX15,EIF3A,ATAD2,SERF2,TXNDC16,CSK,TPP2,CDCA5,DBI,HMGB2,SRSF3,EHD4,CD81 |
| 4.666e-05 | -9.97 | GSE14000_UNSTIM_VS_4H_LPS_DC_UP | MSigDB lists | GSE14000_UNSTIM_VS_4H_LPS_DC_UP | 176 | 47 | 17377 | 2626 |
ZBED3,MMACHC,ATXN3,MTX3,PHF23,POC1A,DBF4,STARD7,SMARCA4,LANCL1,SLC25A44,RCOR3,RSAD1,ZNF275,C2orf68,MOAP1,C12orf10,GTPBP3,CLUAP1,ZNF420,GLIS2,SSBP3,MTA1,POP7,EFTUD2,SLC26A2,CPSF4,FTSJ3,SPSB3,TACC3,ZNF672,NXT1,RFC3,AATF,NOA1,LRRC8A,FRAT2,UBE4B,ASB13,DTWD1,SLC19A1,PEX5,H2AFX,CNOT6,WIPI2,RRS1,DEF6 |
| 4.666e-05 | -9.97 | GSE4142_NAIVE_VS_GC_BCELL_DN | MSigDB lists | GSE4142_NAIVE_VS_GC_BCELL_DN | 176 | 47 | 17377 | 2626 |
KCTD7,NDUFB6,RRP15,URB2,DNAJC24,NUF2,SDF2L1,HAUS2,GTF2F1,LYAR,RRN3,GATC,COQ4,MCM5,ZNHIT6,BANF1,ETV6,GEMIN6,CISD2,POLR1B,MRPL21,MRPL11,TTLL12,STRAP,TACC3,NUDC,PRPF19,EIF5A,RFC3,NASP,HARS,ERF,LAP3,NSUN2,GTPBP4,BCLAF1,NUP155,EXOSC9,MAK16,MAP2K2,SRSF1,STOML2,SUGP1,PDLIM1,CDCA5,RRS1,PDSS2 |
| 4.666e-05 | -9.97 | RPS14_DN.V1_DN | MSigDB lists | RPS14_DN.V1_DN | 176 | 47 | 17377 | 2626 |
SRM,MCM10,REPS2,DEPDC1,MRPS2,CDCA3,PCSK7,KIF23,SLC29A1,KIF2C,ORC1,CD320,USP5,FBXO5,SLC31A1,GATC,SUV39H2,MCM5,PRC1,MSH2,GEMIN4,APOOL,PLK1,TK1,HMGN5,PBK,MRPL12,KIF15,MYBL2,MKI67,TBRG4,KCTD20,CDC6,C14orf132,LLPH,NUP155,GUF1,TWISTNB,EPB41,ATAD2,RRS1,CCNB2,ESPL1,IPO4,GPATCH4,SSSCA1,BYSL |
| 4.704e-05 | -9.96 | VIM (vimentin) | protein interactions | 7431 | 284 | 72 | 17029 | 2761 |
KARS,CYLD,TXN,GXYLT1,IVNS1ABP,DYNLL1,SUMO2,UROD,CUL1,PRKACA,APP,RAD23A,PA2G4,EIF4A3,MTA1,RAD23B,ATF2,HTRA2,DCTN1,CDC5L,COPS8,OSBP2,PSMA8,FAM118B,AKT2,GOPC,KAT7,KIF15,CUL3,NFATC2,MCM2,TRIM28,UBTF,MAN2A2,IDE,DDOST,CHD3,TAB2,ROCK1,COPS6,ARRB2,SMURF1,XRCC4,CAPN1,FUBP1,CASP6,HABP4,FLOT1,XPNPEP3,CDC73,SRRT,AHSA1,MCM5,CREB1,MCPH1,NUP85,EEF1D,SPTAN1,STAU1,TCTEX1D2,FOXK1,PSMA1,PLEC,MEN1,STYXL1,ISG15,RPA1,PDLIM1,ZHX1,CTSA,YWHAZ,CDK2 |
| 4.713e-05 | -9.96 | Helicase_C | pfam domains | PF00271 | 106 | 32 | 17054 | 2545 |
DDX58,RECQL,DDX47,SHPRH,CHD1L,YTHDC2,DHX9,SMARCA4,DHX8,BLM,CHD1,DDX56,EIF4A3,DDX31,DDX28,SNRNP200,DDX24,BTAF1,DHX29,DDX20,DDX39A,DHX15,DHX57,RAD54B,DDX17,DDX23,CHD3,DHX16,DDX5,POLQ,DDX42,DDX52 |
| 4.719e-05 | -9.96 | GSE17721_LPS_VS_POLYIC_24H_BMDC_UP | MSigDB lists | GSE17721_LPS_VS_POLYIC_24H_BMDC_UP | 181 | 48 | 17377 | 2626 |
RAB14,GMFG,TM9SF4,SEC61G,CHD1L,C16orf87,RAB23,B4GALT1,EBNA1BP2,SLC20A1,TMEM165,GLRX3,APP,FAM8A1,MAD2L2,TFRC,WRNIP1,EBP,CSDE1,SNRNP25,COQ4,NOL11,YBX1,SLC35A1,DVL2,MOB4,TXNL1,FTL,POLR2G,RDH10,SUGP2,GTPBP4,WBP2,NUTF2,PNPLA8,METTL22,GFER,CYB5A,GLOD4,CAT,NUCB1,DAP3,WAS,IDE,NIP7,FTSJ1,KPNA2,DVL1 |
| 4.719e-05 | -9.96 | GSE4142_PLASMA_CELL_VS_GC_BCELL_DN | MSigDB lists | GSE4142_PLASMA_CELL_VS_GC_BCELL_DN | 181 | 48 | 17377 | 2626 |
MMACHC,NQO1,GPR89A,DNAJC24,ARF1,GGA2,SAFB2,ITGB5,RSAD1,NUP205,CTNNBL1,VMP1,JAZF1,BANF1,NSFL1C,MSH2,RPF2,TTC4,ECD,MRPL11,TNRC18,TIMM8B,DEAF1,DDX28,SNRNP200,MIOS,EMB,UTP15,NLN,SSR2,MRPL16,EIF2AK1,MTX1,PDE3B,STOML2,IWS1,SUGP1,FNTA,ETS2,ELMO1,RWDD4,DTD1,PDXK,RUVBL2,AKNA,TAF6,GPR89B,ZC3HC1 |
| 4.751e-05 | -9.95 | protein import | biological process | GO:0017038 | 151 | 42 | 17256 | 2622 |
POLA2,TOMM20,NUP188,TSC2,PHB2,RAE1,NUP54,TIMM21,RPAIN,SNUPN,TIMM23,NUP107,TNPO2,TNPO3,NUP153,STAT3,NUP85,TIMM50,TGFB1,PPP3CA,SEC61B,NXT1,NUP155,NUTF2,PTTG1IP,TOMM40,PEX5,KPNA1,TIMM13,HSPA4,KPNA4,TIMM29,TIMM17A,ARNTL,PPP3R1,PML,NUP62,KPNA2,CLU,NUP58,IPO4,NXT2 |
| 4.757e-05 | -9.95 | GSE9988_LPS_VS_LPS_AND_ANTI_TREM1_MONOCYTE_UP | MSigDB lists | GSE9988_LPS_VS_LPS_AND_ANTI_TREM1_MONOCYTE_UP | 186 | 49 | 17377 | 2626 |
NDUFV2,TMED7,GPR132,UGP2,RAC1,CCM2,PLAGL2,CREBL2,RAB11A,BIRC2,MAD2L2,VAV1,RAP1A,VASP,CLIC4,PSMA6,ITGB8,PTEN,CWC27,SNX18,FJX1,FAM89B,ORAI1,FOXN2,ANP32A,GTF3C6,TRIM8,TNFAIP3,BIRC3,ANKRD33B,PFKFB3,DNAJA1,ARID1A,STK17B,SERP1,PLEKHF2,XRCC5,MYO1F,C1orf122,HNRNPR,RPS27A,TAB2,ACOX1,STK38,OAZ2,ZNF436,ATF6,SMG9,PARP10 |
| 4.757e-05 | -9.95 | GSE19888_NO_PRETREAT_VS_ADENOSINE_A3R_INHIBITOR_PRETREATED_MAST_CELL_TCELL_MEMBRANES_ACT_DN | MSigDB lists | GSE19888_NO_PRETREAT_VS_ADENOSINE_A3R_INHIBITOR_PRETREATED_MAST_CELL_TCELL_MEMBRANES_ACT_DN | 186 | 49 | 17377 | 2626 |
BCCIP,GLT8D1,MAPRE1,MRPL42,RWDD1,B4GALT5,DBF4,MCCC1,EBNA1BP2,PDCD7,LYRM2,SCYL2,PIP4K2A,NDUFA2,CWC27,INPP5A,FIZ1,POP7,ZNF260,CISD2,C8orf59,PRADC1,ORC3,MRPL21,RNF135,PPA1,NUDC,GTF3C6,BRD4,AATF,CDC123,FAM118B,SELPLG,MRPS10,EXOSC9,PRKRA,ISG15,BTBD1,CAND1,C1orf122,HHEX,GNA12,ZHX1,HPS5,MRPL27,CTBS,NCOA1,CHID1,ZNF511 |
| 4.757e-05 | -9.95 | GSE19825_NAIVE_VS_IL2RAHIGH_DAY3_EFF_CD8_TCELL_DN | MSigDB lists | GSE19825_NAIVE_VS_IL2RAHIGH_DAY3_EFF_CD8_TCELL_DN | 186 | 49 | 17377 | 2626 |
LZTR1,PLXNC1,TSC2,MRPL42,WDTC1,VPS45,VTI1A,JMJD6,SND1,SAFB2,ABHD14A,MRPL19,FANCL,RB1,SNRNP25,VASP,RRBP1,GTSE1,ATP6V0A2,SUCLG2,PDCD2,RP2,CYB5R1,GEMIN4,ERI3,LPCAT1,CLN6,SYTL3,MOB4,TGFB1,CLPTM1,BTAF1,DENND1B,MTA2,MRPL16,RHBDF2,NECAP2,MOSPD3,INF2,GOLGA2,AGPAT2,LSM6,AP1S1,TMEM219,STK11,TRIM32,COPS6,SNRNP70,TAF6 |
| 4.757e-05 | -9.95 | GSE22313_HEALTHY_VS_SLE_MOUSE_CD4_TCELL_DN | MSigDB lists | GSE22313_HEALTHY_VS_SLE_MOUSE_CD4_TCELL_DN | 186 | 49 | 17377 | 2626 |
GPR132,MCM10,HJURP,CLSPN,POC1A,RRM1,CDCA8,TPX2,KIF23,MXD4,TCF19,LCLAT1,DTL,CCNA2,TBC1D14,RCSD1,FUT8,PRC1,PARL,TNRC18,TACC3,PLK1,RFC3,RHOA,PRIM2,SELPLG,MKI67,RRM2,CDC6,EAF2,GSTCD,SHCBP1,H2AFV,SMAP2,ASF1B,PRIM1,POLE,DSN1,BIRC5,ZNF367,CEP55,PRMT7,C4orf46,PRPF4,KPNA2,LTA4H,CCNB2,NUDT3,DEF6 |
| 4.757e-05 | -9.95 | GSE5542_UNTREATED_VS_IFNG_TREATED_EPITHELIAL_CELLS_24H_UP | MSigDB lists | GSE5542_UNTREATED_VS_IFNG_TREATED_EPITHELIAL_CELLS_24H_UP | 186 | 49 | 17377 | 2626 |
WSB2,LUZP1,SRGN,UCK2,MXD4,GGA2,RGS2,GIT2,CAPN2,LYAR,RB1,ATP6V0B,SLC1A4,PPP4R1,ZNF335,ARL6IP1,JOSD1,CLDND1,CNOT6L,MYBL1,F2R,SYTL3,MICAL3,EMB,RDH10,SEPT8,EZR,ATXN1,ARHGEF12,NFATC2,OGDH,IL12RB1,TOLLIP,EIF3A,RHBDF2,OPTN,MYO1F,FAS,PI4K2A,CACNB1,ITPRIPL1,AHNAK,SURF4,ODF2,ITGB1,MBOAT1,PDXK,LRP8,NIPA1 |
| 4.757e-05 | -9.95 | GSE17721_0.5H_VS_24H_POLYIC_BMDC_UP | MSigDB lists | GSE17721_0.5H_VS_24H_POLYIC_BMDC_UP | 186 | 49 | 17377 | 2626 |
PPIB,C19orf53,MRPS2,SUZ12,ANKH,HAUS4,PABPC4,EBP,LYAR,RRN3,RAP1A,SMC3,AHCTF1,CCNA2,TNFAIP8,INTS1,DAPK1,AKR1B1,MRPL48,OSTC,TALDO1,LRRC59,PHKG2,NUP85,IMPA2,EIF5A,PPP1R18,TIMMDC1,PPIE,MYBL2,RPL6,TBRG4,ADSL,CAPZA2,MCM2,ABCF1,BTBD1,DUS3L,PITX1,RPLP1,H2AFX,MLYCD,PRMT7,ANP32E,CENPT,CD81,AAAS,PFKP,IPO4 |
| 4.757e-05 | -9.95 | GSE5589_LPS_VS_LPS_AND_IL10_STIM_IL6_KO_MACROPHAGE_180MIN_UP | MSigDB lists | GSE5589_LPS_VS_LPS_AND_IL10_STIM_IL6_KO_MACROPHAGE_180MIN_UP | 186 | 49 | 17377 | 2626 |
MBD1,TCF12,LZTR1,ZNF445,ZCCHC8,MAGED1,BRAP,PPP3CB,EIF1B,CRLF3,GNB2,TFAP4,STARD9,VASP,TBC1D14,PHF14,ADCY9,PPP1R12C,SRI,KIFAP3,UBE3B,ZNF710,PIKFYVE,RNF135,RYBP,KDM3B,ADAM17,ERLIN1,HSDL1,SEPT8,CAPZA2,ADRB2,PLEC,WDR81,RPL27A,KLF6,USP21,SFXN5,CAT,PWWP2B,GNA12,PPP2R5A,ZDHHC7,TMEM101,MAP3K5,FAU,ARRB2,GLCCI1,PDSS2 |
| 4.783e-05 | -9.95 | GSE20366_EX_VIVO_VS_HOMEOSTATIC_CONVERSION_TREG_UP | MSigDB lists | GSE20366_EX_VIVO_VS_HOMEOSTATIC_CONVERSION_TREG_UP | 191 | 50 | 17377 | 2626 |
GNPNAT1,AGRN,SLC41A1,MUM1,CERK,MED13L,CHIC2,ADCK5,CCNL2,ASXL2,LCLAT1,ANKIB1,CCDC28A,NUDT19,HOMER1,PHTF1,TRMU,SUCLG2,UPF2,CEP63,PIK3IP1,PLCL2,SLC35C2,F2R,PHKG2,MGAT5,SPSB3,CSTF1,SRSF11,PLK3,TELO2,STAU1,CYFIP1,KIAA0040,CAMSAP1,DNAJA1,FKBP3,SLTM,RPS9,PHF6,SMAP2,XRCC5,TBC1D17,PITX1,CANT1,WIPI2,BRD9,CABLES1,LONP2,ALS2 |
| 4.783e-05 | -9.95 | GSE14769_UNSTIM_VS_240MIN_LPS_BMDM_DN | MSigDB lists | GSE14769_UNSTIM_VS_240MIN_LPS_BMDM_DN | 191 | 50 | 17377 | 2626 |
OTUD5,UBE2E2,FAM208B,FEZ2,SESTD1,FAM53C,FAM129A,TOR3A,SRGN,C5orf30,PLAGL2,UBE2Z,SLC25A12,AGFG1,CHAC2,BIRC2,CLIC4,CBWD2,FBXO7,TANK,ATP6V0A2,RNF135,MVP,PLCL2,STAT3,ZNF800,ARID4A,CGGBP1,SEH1L,VOPP1,ZDHHC18,NCK1,PGS1,USP42,MIER1,SLC25A22,RAB3IP,ZNF407,RAB22A,KRIT1,DTWD1,TRIM26,VCPIP1,SLAIN1,RGL1,PLOD3,BRWD3,TRAF5,RNF114,LRCH1 |
| 4.783e-05 | -9.95 | GSE411_UNSTIM_VS_100MIN_IL6_STIM_SOCS3_KO_MACROPHAGE_DN | MSigDB lists | GSE411_UNSTIM_VS_100MIN_IL6_STIM_SOCS3_KO_MACROPHAGE_DN | 191 | 50 | 17377 | 2626 |
HIVEP3,UBL3,IER2,FGFR1OP,PKP4,GPR132,C19orf53,ZCCHC9,DNAJB2,DAP,SRGN,KCTD17,RRAGC,APP,DAD1,CRAT,TBC1D14,CLDND1,CDC25B,GPD1L,ATP6V0D1,ABI1,S100A6,RYBP,SNX25,ANKRD37,NEK7,COQ10B,LNX2,EMP3,PNPLA8,PICALM,ARHGAP15,PI4K2A,FAS,SH3BP5,NSA2,TXNDC16,SNAP29,TATDN2,TPP2,PPM1G,MAP4,PPP1R11,PITPNA,ZNF830,BRWD3,IGBP1,NRBP1,SLC25A33 |
| 4.797e-05 | -9.94 | SHEPARD_BMYB_MORPHOLINO_UP | MSigDB lists | SHEPARD_BMYB_MORPHOLINO_UP | 201 | 52 | 17377 | 2626 |
SNX27,FAM207A,DLGAP4,OLA1,UCK1,KLC1,PTP4A3,GLUD1,NENF,AGFG1,SDF2L1,GYG1,SND1,FOXO3,MRPL19,CPNE3,GNS,SLC31A1,MDM2,MBD2,SRSF4,PRC1,ZC3H3,HTRA2,ABCC5,RPAP3,TIMP2,CIC,LYRM1,RDH10,PARP4,FXR1,SPPL2B,USP36,PRDX1,DNAJC10,TRIM47,TPD52L2,ATP1A1,PLAA,DUS3L,RBM25,ZNF330,PSMD3,TYW5,SH3GLB2,LY75,CBWD1,NCLN,SCARB1,OSGEPL1,GCSH |
| 4.809e-05 | -9.94 | endoplasmic reticulum part | cellular component | GO:0044432 | 1314 | 245 | 18223 | 2701 |
TMED7,PIGM,PDCD6IP,TMEM203,COPA,ADAM10,PRKCSH,PIGQ,TMEM109,MOGS,AGPAT1,TAP1,TGOLN2,CDIPT,FKBP2,IKBIP,SEC16A,BECN1,RNF103,SSR1,DST,NUP210,CDC42,THADA,RAB35,CYB5RL,SRI,ZFYVE27,CISD2,MARCH2,RNF26,TFG,TECR,SPTSSA,LRRC59,PGAP2,DPM1,ATG9A,APH1A,SUMF2,ESYT1,PITPNB,ICMT,MCFD2,KRTCAP2,RAB2B,RHEB,ALG3,AGPAT2,STT3A,TMED10,RPS27A,MIA2,SARAF,PIEZO1,CLN3,RPS26,RTN3,STARD3NL,SVIP,PPIB,PIGN,AGTRAP,SEC61G,DNAJB2,HLA-E,UBXN1,SDC2,SLC35B1,RAB6A,TMED3,NOTCH2,PSEN1,COPG2,RHBDD1,NPLOC4,COPB2,DDRGK1,CD59,FKBP1A,RPN1,RNF121,NUS1,PYURF,LRRC8D,RNFT1,DAD1,EI24,ARL6IP1,PIGG,RTCB,SLC27A4,BCL2,PCYT2,MYDGF,LPCAT1,TMED2,APOL1,PREB,FDFT1,KDELR1,EIF5A,PIGT,SIGMAR1,RB1CC1,ERLIN1,NSDHL,ACSL3,ERO1A,RDH10,MAN1B1,SSR2,SYVN1,VKORC1,CYB5A,RDH11,DERL1,SEC31A,MOSPD3,SCARB2,GALNT2,ORMDL2,TXNDC16,ERGIC3,LPCAT4,SIL1,VCPIP1,SAMD8,SMPD4,MAP3K5,TMEM14A,PTDSS1,APOL2,RNF139,TMEM106C,RHOG,ATXN3,CHERP,COPE,RAC1,VTI1A,TMEM97,ADPGK,SLC35B2,LCLAT1,KTN1,APP,EXT2,BCAP31,SEC11A,APLP2,RAB21,ATP2A2,LPIN2,TAP2,ANKRD13C,BCAP29,RPN2,CYB5R1,MINPP1,LMAN1,AHCYL1,CLN6,PDIA6,HTRA2,MOSPD1,ANKLE2,ACSL5,UBQLN4,SEC61B,ATP13A1,ERMP1,TOR1AIP2,PKMYT1,TMEM147,DNAJA1,RAB1A,EDEM2,SERP1,RHBDF2,DNAJC10,SURF4,DDOST,SEC61A1,CERS6,SCAP,SEL1L,CANT1,NCLN,MBOAT1,ATF6,REEP4,ABCA1,TMEM33,CDS2,TOR3A,TMX3,AGPAT3,SUMF1,SDF2L1,REEP5,WRB,DNAJB9,HLA-A,SPPL2A,EBP,GOLM1,CAPN2,SEC24C,RRBP1,SLC35B4,ATG13,YIF1B,OSTC,CNPY3,CAMK2G,TMX1,RNF5,ELOVL5,MLEC,RHOA,PNPLA8,WDR81,MEN1,ARSK,SPPL2B,YIF1A,HLA-B,RAB18,NUCB1,PLD3,PDCD6,MAGT1,WNT5B,OSBPL8,DBI,STX18,PML,PGRMC1,ASNA1,PKD2,SPCS3,PLOD3,FAF1,ESYT2 |
| 4.815e-05 | -9.94 | positive regulation of DNA metabolic process | biological process | GO:0051054 | 200 | 52 | 17256 | 2622 |
USP7,FOXM1,CHTF18,MECP2,EYA1,CDT1,BABAM1,RAC1,DHX9,DBF4,PARN,TFRC,HNRNPA2B1,PCNA,BABAM2,TIGAR,NVL,MSH2,NABP2,TIMELESS,PTGES3,DNMT1,SPIDR,MSH6,TGFB1,CCT2,ERCC1,EXOSC6,RFC3,NEK7,MRNIP,BRCA1,AURKB,RFC2,TRIM28,CCT8,MAPK3,STOML2,XRCC5,MAP3K4,STAT6,PML,CEBPG,H2AFX,ARRB2,SLF1,MAPK1,CDK2,POT1,HRAS,SLF2,EYA2 |
| 4.821e-05 | -9.94 | antigen processing and presentation | biological process | GO:0019882 | 210 | 54 | 17256 | 2622 |
KIF3B,HLA-E,DYNLL1,DCTN2,TAP1,KLC1,KIF23,RACGAP1,ARF1,KIF2C,RAB6A,AP1B1,ITGB5,PSMD9,BCAP31,HLA-A,PSMD2,CTSS,PSMA6,PSMD1,RAB35,SEC24C,RAB4A,CAPZA1,DNM2,AP1M1,AP2B1,KIFAP3,KIF22,TAP2,DCTN1,PSMA8,RAB7A,PSMB7,KIF15,PSMA1,CAPZA2,RAB5B,PSMB9,KIF11,PSMB3,PSMC4,KIF2A,CTSL,SEC31A,HLA-B,KIF18A,PSMD8,PSMD3,SNAP23,AP1S1,AP2S1,PSMC1,DYNC1LI2 |
| 4.821e-05 | -9.94 | HERPUD1 (homocysteine inducible ER protein with ubiquitin like domain 1) | protein interactions | 9709 | 32 | 15 | 17029 | 2761 |
DERL1,RPA2,USP7,STARD9,PSMD2,UBQLN4,EWSR1,SIAH1,ATG9A,SYVN1,UBQLN2,PSEN1,TOLLIP,APP,IMPA2 |
| 4.821e-05 | -9.94 | MTERF3 (mitochondrial transcription termination factor 3) | protein interactions | 51001 | 32 | 15 | 17029 | 2761 |
MRPL50,DDX28,RBM42,AGTRAP,MRPL39,RBMX,RPL6,ARL6IP1,UPF2,HNRNPDL,SDHA,ZC3H3,APP,DDRGK1,CAND1 |
| 4.821e-05 | -9.94 | TRMT112 (tRNA methyltransferase subunit 11-2) | protein interactions | 51504 | 32 | 15 | 17029 | 2761 |
SRSF11,SART1,SYNCRIP,SCOC,THOC1,SAFB,LUC7L3,SF3B1,SRSF5,SRSF3,DHX15,IPO4,SRSF1,CAND1,SRSF10 |
| 4.865e-05 | -9.93 | FUBP1 (far upstream element binding protein 1) | protein interactions | 8880 | 107 | 34 | 17029 | 2761 |
RPS15,IMMT,MRPL42,ACTR3,SPR,PCBP1,NDUFS4,MDM2,DUT,CNN2,ATF2,RPRD1B,MRPL32,PCBP2,LAP3,NSUN2,CUL3,USP22,MCM2,RAB1A,PKM,TOMM40,ARF4,RPA1,PLD3,MRPL2,PDCD6,CHD3,PRDX5,SRSF3,PPP5C,CD81,CDK2,ANXA11 |
| 4.865e-05 | -9.93 | NPLOC4 (NPL4 homolog, ubiquitin recognition factor) | protein interactions | 55666 | 107 | 34 | 17029 | 2761 |
TRIP10,RAF1,UBXN1,DNAAF5,FLOT1,UBQLN2,MRPL19,LMNA,EIF4A3,RAD23B,NSFL1C,MTPN,RPRD1B,KDELR1,DCTN1,METTL1,RPRD1A,ATG9A,ADSL,RRM2,MTMR12,ADRB2,MCM2,PKM,PICALM,PTPRF,HNRNPR,WDR4,VCPIP1,FUS,PDLIM5,FAF1,USP13,SVIP |
| 4.881e-05 | -9.93 | SWEET_KRAS_ONCOGENIC_SIGNATURE | MSigDB lists | SWEET_KRAS_ONCOGENIC_SIGNATURE | 87 | 28 | 17377 | 2626 |
RPS2,FEZ2,TSTA3,PHB2,UBXN1,RPL6,RPL8,TGOLN2,SND1,FKBP2,SLC25A5,PSEN1,MAN1A1,GNS,PON2,VASP,CTSS,SHC1,AXIN1,FAM3C,TANK,ACLY,CITED2,MAPK1,SLC12A2,PABPC1,EEF1D,KDELR1 |
| 4.881e-05 | -9.93 | GO_MITOCHONDRIAL_MEMBRANE_ORGANIZATION | MSigDB lists | GO_MITOCHONDRIAL_MEMBRANE_ORGANIZATION | 87 | 28 | 17377 | 2626 |
PPIF,BAK1,IMMT,TOMM20,DYNLL1,HEBP2,BCL2L1,RHOT1,SLC25A5,RHOT2,TAZ,CHCHD6,MFN2,MOAP1,CHCHD3,HSPA4,SIVA1,TFDP1,PPP3R1,E2F1,BCL2,YWHAZ,TP53BP2,YWHAH,STAT3,ATF2,EYA2,TIMM50 |
| 4.886e-05 | -9.93 | HIRA (histone cell cycle regulator) | protein interactions | 7290 | 39 | 17 | 17029 | 2761 |
UBN1,MECP2,CUL3,MEF2A,NFATC2,MEF2D,UBE2I,ASF1B,POLR2A,TFAP4,CCNA2,UPF1,PML,CABIN1,NFU1,H3F3A,CDK2 |
| 4.886e-05 | -9.93 | EIF3CL (eukaryotic translation initiation factor 3 subunit C like) | protein interactions | 728689 | 39 | 17 | 17029 | 2761 |
EIF3L,RPS2,RPL35,EIF3D,CUL3,RPS24,SND1,MCM2,EIF3G,APPL1,EIF3H,EIF3A,RPL23A,EIF3K,CLTB,CD81,RPS26 |
| 4.886e-05 | -9.93 | E2F2 (E2F transcription factor 2) | protein interactions | 1870 | 39 | 17 | 17029 | 2761 |
MYBL2,CDC6,GIT2,JMY,RB1,ATAD2,BRD2,RBL1,E2F4,KMT5A,UCHL5,TFDP1,E2F1,TP53BP2,TFDP2,YY1,RYBP |
| 4.887e-05 | -9.93 | Apoptosis | REACTOME pathways | R-HSA-109581 | 172 | 49 | 10287 | 1696 |
ADD1,CLSPN,CASP6,DYNLL1,MAGED1,XIAP,CYCS,BCL2L1,PSMD9,BIRC2,BCAP31,LMNA,CFLAR,PSMD2,PSMD1,PSMA6,DAPK1,BCL2,TP53BP2,SPTAN1,BAK1,PSMA8,AKT2,PSMB7,PSMA1,PLEC,PSMB9,APPL1,PSMB3,FADD,DAPK3,PSMC4,FAS,KPNA1,FNTA,RPS27A,PSMD8,PSMD3,TFDP1,PPP3R1,E2F1,HMGB2,TICAM1,YWHAZ,ROCK1,GAS2,TFDP2,YWHAH,PSMC1 |
| 4.891e-05 | -9.93 | EAPP (E2F associated phosphoprotein) | protein interactions | 55837 | 50 | 20 | 17029 | 2761 |
UBQLN4,SNRNP200,XAB2,SNRPB,CRNKL1,E2F3,DHX8,USP39,SNRPD3,NCDN,DDX23,EFTUD2,E2F1,GPATCH1,ECD,AQR,RUVBL2,E2F2,CDC5L,PRPF19 |
| 4.891e-05 | -9.93 | E2F3 (E2F transcription factor 3) | protein interactions | 1871 | 50 | 20 | 17029 | 2761 |
MYBL2,CDC6,CCNB1,TRIM28,JMY,USF1,RB1,CCNA2,PCNA,ATAD2,RBL1,BIRC5,UCHL5,TFE3,TFDP1,MSH2,TP53BP2,YY1,TFDP2,RYBP |
| 4.891e-05 | -9.93 | DUSP11 (dual specificity phosphatase 11) | protein interactions | 8446 | 50 | 20 | 17029 | 2761 |
RPS15,RPS2,THOC1,MRPS2,MRPS15,MRPS26,KCTD17,MRPS10,KIF11,MRPL19,MRPL50,DAP3,RPL32,SYNCRIP,QARS,DUSP11,PTGES3,MRPL21,MRPL13,TERF2 |
| 4.891e-05 | -9.93 | ATP6V1D (ATPase H+ transporting V1 subunit D) | protein interactions | 51382 | 50 | 20 | 17029 | 2761 |
USP7,SNX8,RPS15,DDX28,ATP6V0A1,ATP6V1B2,COMMD4,COMMD8,PPP2CA,SEC31A,GOLGA2,UBA5,MPV17,ATP6V0A2,MRPL40,MCMBP,MAPK1,PSMC1,ATP6V0D1,ATP6V1G1 |
| 4.891e-05 | -9.93 | RPE (ribulose-5-phosphate-3-epimerase) | protein interactions | 6120 | 50 | 20 | 17029 | 2761 |
PPCS,RHOA,AKT2,MRI1,TRIO,TKT,ADSL,NUTF2,PRKACA,MAP2K2,CDK5,ADSS,IDE,ACLY,DNM2,CLU,TALDO1,CDK2,NRBP1,IMPA2 |
| 4.899e-05 | -9.92 | DDX20 (DEAD-box helicase 20) | protein interactions | 11218 | 90 | 30 | 17029 | 2761 |
NCOR2,USO1,ETV3,COPA,PHB2,PRRC2A,SNRPB,TCF3,AGO2,DHX9,RNPS1,DDX20,EIF2AK1,DCLRE1C,SNRPD3,GAR1,APP,GEMIN5,SNUPN,MFAP1,GEMIN6,CRY2,GEMIN4,SNRPG,FBL,SNRNP70,CLN3,STRAP,HDAC2,GEMIN7 |
| 4.899e-05 | -9.92 | ATP6V1A (ATPase H+ transporting V1 subunit A) | protein interactions | 523 | 90 | 30 | 17029 | 2761 |
TXNL1,DDX28,TK1,UBXN1,XIAP,VDAC2,TUFM,CUL3,COX4I1,RAB1A,ATP6V1B2,VDAC1,USP5,RPA2,RPN1,ATP6V1D,ATP1A1,PDCD10,DDOST,EIF4A3,SUCLG2,CHMP4B,AHCY,ACADM,ATP5F1A,RBBP4,MCMBP,ATP6V0D1,MTPN,CAPN1 |
| 4.909e-05 | -9.92 | ANXA2P2 (annexin A2 pseudogene 2) | protein interactions | 304 | 11 | 8 | 17029 | 2761 |
RPA2,MCM5,H2AFX,FUS,MCM2,SMURF1,USP53,RPA1 |
| 4.909e-05 | -9.92 | PSPH (phosphoserine phosphatase) | protein interactions | 5723 | 11 | 8 | 17029 | 2761 |
FLAD1,ATXN1,TIMM8B,SHC1,PRPSAP1,STYXL1,ASF1B,OGT |
| 4.930e-05 | -9.92 | PID_ERBB1_DOWNSTREAM_PATHWAY | MSigDB lists | PID_ERBB1_DOWNSTREAM_PATHWAY | 105 | 32 | 17377 | 2626 |
WASF2,PDPK1,NRAS,RAF1,RAC1,ACTR3,VAV2,KRAS,BCL2L1,NCKAP1,CYFIP2,ELK1,MAP2K2,ARF4,MAPK3,CAPN2,PPP2CA,CDC42,ARPC5,PIK3R2,STAT1,YWHAZ,CREB1,PPP5C,SMAD1,ATF2,STAT3,YWHAH,MAPK1,ABI1,HRAS,MLST8 |
| 4.961e-05 | -9.91 | FTSJ3 (FtsJ RNA methyltransferase homolog 3) | protein interactions | 117246 | 129 | 39 | 17029 | 2761 |
NIFK,NOP2,DHX8,CUL1,CSNK2A1,EBNA1BP2,BRIX1,PAIP1,PTPN2,DDX56,RBM34,ZNF746,NOC2L,RPF2,NAP1L4,FBL,ZC3H3,HP1BP3,CDC5L,NOL12,SRP72,STAU1,DDX24,ZNF512,SF3B6,CUL3,RPL8,RPL6,MAK16,PSMC4,CAND1,NSA2,DGCR8,TBL3,RRS1,DDB1,GPATCH4,IFI16,BYSL |
| 4.961e-05 | -9.91 | IRAK1 (interleukin 1 receptor associated kinase 1) | protein interactions | 3654 | 129 | 39 | 17029 | 2761 |
IMMT,ST13,MAGED1,SLC2A1,YTHDC2,CUL1,PPP3CB,ATP5F1B,SEC16A,MAPK14,HLA-A,LMNA,IRF4,CEP104,VASP,TARDBP,STAT3,TIMM50,CDC37,CCT2,SNRNP200,TNFAIP3,COQ8A,HNRNPF,CUL3,DNAJA1,RHOT1,TOLLIP,CCT8,FADD,OPTN,PPP2CA,ATP1A1,HSPA4,TAB2,STAT1,TRIM32,CLN3,HRAS |
| 4.972e-05 | -9.91 | protein import into nucleus | biological process | GO:0006606 | 100 | 31 | 17256 | 2622 |
TGFB1,POLA2,PPP3CA,SEC61B,NUP188,NXT1,TSC2,PHB2,RAE1,NUP54,NUP155,NUTF2,PTTG1IP,RPAIN,KPNA4,SNUPN,KPNA1,ARNTL,NUP107,PML,PPP3R1,TNPO3,TNPO2,NUP62,NUP153,KPNA2,STAT3,NUP85,NUP58,IPO4,NXT2 |
| 4.983e-05 | -9.91 | GO_REGULATION_OF_BINDING | MSigDB lists | GO_REGULATION_OF_BINDING | 278 | 67 | 17377 | 2626 |
TXN,ADD1,SIRT2,PRKACA,APP,PARK7,CALM2,CDK5,SP100,CDC42,EIF4A3,RALB,PIN1,SRI,PLCL2,CARM1,PLK1,CPNE1,BAK1,AURKB,EDF1,BTBD1,EPB41,KRIT1,DOT1L,SMAD2,HIPK2,ZNF268,TICAM1,DVL1,ROCK1,ARRB2,SMAD4,HDAC2,MAPRE1,HJURP,HABP4,FLOT1,PSEN1,CSNK1A1,MAD2L2,FKBP1A,TFAP4,IRF4,GTSE1,BCL2,TGFB1,PPP3CA,KAT2A,BTAF1,MFNG,GTPBP4,PACS1,ADRB2,MEN1,MAPK3,DERL1,PTPRF,GOLGA2,E2F1,CEBPG,PRMT7,ZFP90,HMGB2,RUVBL2,IFI16,SNAPIN |
| 4.984e-05 | -9.91 | GNF2_G22P1 | MSigDB lists | GNF2_G22P1 | 34 | 15 | 17377 | 2626 |
ZNF207,KARS,MRPL9,PSMA6,UTP18,QARS,SUMO2,PSMB7,TRA2B,NUP62,SRSF3,SNRPD3,UBE2I,RBM4,DHX15 |
| 4.999e-05 | -9.90 | GTGCCTT,MIR-506 | MSigDB lists | GTGCCTT,MIR-506 | 684 | 141 | 17377 | 2626 |
FGFR1OP,TMEM184B,UBN1,TMEM109,YTHDF3,SLC29A1,MAPK14,RUFY1,DLG5,DNM2,NRAS,SEPT9,NSUN2,GMFB,SREK1,SLC17A5,RAB22A,ABHD5,TRAM2,MID1IP1,BRWD1,TMED10,AXIN1,ITGB1,ARRDC1,GALNT10,DCAF5,CAPN1,ANXA11,HIVEP3,PRPF38B,UBXN1,B4GALT1,PSEN1,WDR48,TFAP4,DAPK1,PIK3IP1,RNF135,MAML1,GNAI2,SLC12A2,FAM171A1,LUC7L2,ALDH9A1,ZNF189,SOCS5,RB1CC1,RDH10,PIP4K2C,FAM133B,PLEC,PTTG1IP,MTR,CYB5A,PHF6,SERTAD2,OSBPL11,CCDC86,USP32,FAM122A,SLC16A1,PITPNA,WIPI2,C7orf26,NIPA1,RNF114,ADNP2,RHOG,ANKRD27,RPS6KA1,STARD7,MYH9,LCLAT1,SHC1,WDR44,GRSF1,ADCY9,FAM76B,CTDSP2,PPIF,KAT7,OAF,BTG2,E2F3,WIPF1,HTATIP2,CADM1,BICD2,ARL5B,SERP1,MAT2A,KIF2A,VEZF1,ATP1A1,RBL1,STK38,ZBTB11,EYA2,ABCA1,SLC25A39,EYA1,SRSF6,SESTD1,TOR3A,FAM76A,FLOT1,KLF13,CHIC2,SUMF1,NKRF,MXD4,UBE4A,AKT1S1,SDF2L1,GGA2,TFRC,SPPL2A,CRAT,PTPN11,ABCD1,CLDND1,ST8SIA2,STAT3,SLC25A1,TSHZ1,MLEC,RFFL,WDR81,LRRC1,TFEB,LEMD2,TPD52L2,PDCD6,KPNA4,MAGT1,TWSG1,OSBPL8,ZRANB2,PLOD3,ESYT2 |
| 5.002e-05 | -9.90 | NF2 (neurofibromin 2) | protein interactions | 4771 | 212 | 57 | 17029 | 2761 |
HSPH1,PRPF38B,ZBTB10,RPS2,PDCD6IP,CYLD,DYNLL1,RPL15,SLC25A12,CLCC1,CCNL2,IKBIP,CPNE3,PABPC4,CDK5,RPA2,FARSA,DECR1,SMC3,PPP1R8,GRSF1,MVP,LPCAT1,SLC25A1,PREB,PRPF19,RFC3,TSPYL4,WBP2,PIP4K2C,RPL8,EZR,C1orf35,SLC25A22,DNAJA1,RIT1,SLC25A5,PEF1,PDHX,DHX15,PRDX1,RPA1,XRCC5,SUPT16H,LEMD2,TSC1,HGS,PDCD6,HSPA4,LUC7L3,ITGB1,CHMP4B,KPNA2,RBBP4,XRCC4,DDB1,SSRP1 |
| 5.028e-05 | -9.90 | RPL28 (ribosomal protein L28) | protein interactions | 6158 | 138 | 41 | 17029 | 2761 |
RPS15,COX15,RPS2,CYLD,RPLP2,KLHL21,KIAA0232,CUL1,BRIX1,RPL23A,PA2G4,EIF4A3,RBM34,GRSF1,ZNF746,RPL19,TARDBP,FTSJ3,PTPRK,STAU1,RPL35,CELSR2,RPS10,RPL8,RPL38,RPL6,BRCA1,VDAC1,MCM2,KIF11,CENPU,CAND1,RPL36,POLE,RPL32,KLHL15,RPS14,RPLP1,CDK2,ARRB2,SMAD4 |
| 5.028e-05 | -9.90 | DDX1 (DEAD-box helicase 1) | protein interactions | 1653 | 138 | 41 | 17029 | 2761 |
MCCC1,DHX9,CUL1,C2orf49,UBE2I,SDHA,RBM4,APP,HNRNPA2B1,RPA2,VASP,HUWE1,PPP1R8,RTCB,YBX1,ALDH18A1,FGFR1OP2,HNRNPM,STAU1,RHOA,TSTA3,STRIP1,CUL3,BRCA1,MCM2,RFC2,PICALM,FKBP3,ABCF1,CAND1,RPA1,GEMIN5,EIF3K,SCARB2,PDCD6,QARS,FUS,PLOD3,CDK2,ARRB2,ECPAS |
| 5.042e-05 | -9.90 | regulation of cellular response to heat | biological process | GO:1900034 | 78 | 26 | 17256 | 2622 |
DNAJC2,HSPH1,NDC1,NUP188,RAE1,NUP54,NUP155,AKT1S1,DNAJB1,NUP205,MAPK3,HSPA1B,RPA1,RPA2,NUP210,NUP107,NUP62,NUP153,PTGES3,MAPK1,NUP58,NUP85,AAAS,CAMK2G,SEH1L,MLST8 |
| 5.065e-05 | -9.89 | HMG14_17 | prosite domains | PS00355 | 5 | 5 | 12060 | 1670 |
HMGN3,HMGN1,HMGN5,HMGN4,HMGN2 |
| 5.111e-05 | -9.88 | GCM_NCAM1 | MSigDB lists | GCM_NCAM1 | 119 | 35 | 17377 | 2626 |
WSB2,SMAP1,MECP2,ADO,RBM8A,FOXO3,ABHD14A,HMG20A,FAM8A1,REPS1,PAIP1,FBXO3,ASAP2,BRPF3,RABGAP1L,SS18L1,AHDC1,CHTOP,CLCN3,ZNF84,TSPYL4,KAT7,NUDT4,ACSL3,CRNKL1,USP22,CADM1,ZFAND5,BSDC1,CAND1,MTMR3,SCARB2,EIF4ENIF1,VPS26B,ALS2 |
| 5.117e-05 | -9.88 | GABARAPL2 (GABA type A receptor associated protein like 2) | protein interactions | 11345 | 86 | 29 | 17029 | 2761 |
RPS2,AGTRAP,CUL3,EZR,VDAC1,MAP1LC3B,GOSR1,TSR2,APP,OPTN,ATG4A,RAP1A,KEAP1,MLX,KLHL5,NSF,ATG3,UBA5,KBTBD7,LRPPRC,HADHB,ATG13,YWHAZ,WDR62,MCPH1,LRSAM1,NIPSNAP2,TMEM160,NIPSNAP1 |
| 5.117e-05 | -9.88 | NOC2L (NOC2 like nucleolar associated transcriptional repressor) | protein interactions | 26155 | 86 | 29 | 17029 | 2761 |
NIFK,NOP2,AATF,DDX24,ZNF512,MECP2,MAGED1,GTPBP4,EBNA1BP2,AURKB,MPG,MAK16,APP,DHX15,NSA2,DDX56,MDM2,JAK1,RPS14,RBM34,TBL3,ZNF746,RPF2,DDX31,RRS1,FBL,FTSJ3,IFI16,DDX52 |
| 5.117e-05 | -9.88 | AARSD1 (alanyl-tRNA synthetase domain containing 1) | protein interactions | 80755 | 86 | 29 | 17029 | 2761 |
SRM,TP53RK,PPP1R12A,LUZP1,LAP3,HARS,UBXN1,SEPT8,USP10,UBQLN2,BORA,ARPC1A,PRKACA,NCAPG,TARS,SH3GLB1,RPA1,PFDN5,TPD52L2,ARPC5,HPS5,FBXO7,EFTUD2,SH3GLB2,SASS6,ARRB2,RPRD1B,POC5,FUBP1 |
| 5.161e-05 | -9.87 | REACTOME_TRANSPORT_OF_RIBONUCLEOPROTEINS_INTO_THE_HOST_NUCLEUS | MSigDB lists | REACTOME_TRANSPORT_OF_RIBONUCLEOPROTEINS_INTO_THE_HOST_NUCLEUS | 27 | 13 | 17377 | 2626 |
NUP188,NUP210,KPNA1,RAE1,NUP107,NUP54,NUP62,NUP153,NUP155,NUP85,AAAS,NUP205,SEH1L |
| 5.177e-05 | -9.87 | V$USF2_Q6 | MSigDB lists | V$USF2_Q6 | 237 | 59 | 17377 | 2626 |
PPCS,SCAMP3,RRP15,IVNS1ABP,ZFP91,SCYL1,UBXN1,RRAGC,EBNA1BP2,TAF6L,RLF,STMN1,PABPC4,CSDE1,CDKN2C,ATP6V0B,PA2G4,SMC3,ARPC5,ZNHIT6,YBX1,TAGLN2,FAM76B,ALDH18A1,CCAR1,CFL1,NUDC,AMPD2,B3GALT6,NRAS,POLR2L,NET1,HNRNPF,LDHA,PFKFB3,UBE4B,KRTCAP2,PICALM,EIF3A,EPB41,HMGN2,ADSS,PTPRF,ALDH3B1,HHEX,SEC23IP,CCDC6,HNRNPH3,HPS5,SLC16A1,RGL1,RBBP4,LRP8,FAF1,SLC25A33,B4GALT2,RAB3IL1,RHEBL1,ATXN7L2 |
| 5.202e-05 | -9.86 | vacuolar part | cellular component | GO:0044437 | 571 | 119 | 18223 | 2701 |
ADA2,RAB14,AGRN,ABCC10,HEXB,RRAGC,NHLRC3,GYG1,AP1B1,ATP6V1B2,MAP1LC3B,CMTM6,CPNE3,GNB2,GLMP,PCYOX1L,NAPG,PA2G4,ATP6V0B,PSMD1,AP1M1,CLCN6,BRI3,AP2B1,RPN2,MARCH2,TMEM9,TMBIM1,GM2A,DRAM2,SEH1L,ATP6V1G1,WDR41,CPNE1,CCT2,MIOS,ATG9A,PPT1,GOPC,RAB7A,ARHGAP45,ATP6V0A1,SLC17A5,TOLLIP,RHEB,PLEKHF2,AHNAK,DSN1,WDR11,SURF4,DDOST,NAGLU,WDR59,AP1S1,ATP6V0C,SCARB1,VPS4A,CLN3,MAPK1,AP2S1,CHID1,TUBB,STARD3NL,DNAJC5,ANXA6,CCZ1,MANBA,CDIP1,FLOT1,LAMTOR3,SDC2,ASAH1,B4GALT1,MAN2B1,PSEN1,TMEM165,TMEM179B,SPPL2A,GNS,CTSS,ZNRF2,VMP1,ATP6V0A2,TMEM8A,LPCAT1,ATP6V0D1,TPCN1,MFSD12,ABCC1,FTL,ACP2,GALC,CREG1,GBA,HEBP2,WDR81,CCT8,SPPL2B,NEU1,RMC1,SH3GLB1,PI4K2A,CTSL,SCARB2,SGSH,ATP6V1D,MAGT1,NSF,CCZ1B,SNAP29,LAMTOR4,ACLY,IMPDH1,CTSA,PSAP,ATP6V1C1,HEXA,SNX14,SNAPIN |
| 5.203e-05 | -9.86 | Leptin signaling pathway | WikiPathways | WP2034 | 76 | 26 | 5312 | 837 |
RHOA,RAF1,RPS6KA1,RAC1,PRKAA1,BCL2L1,ELK1,MAPK14,PDE3B,MAP2K2,MAPK3,SOCS7,KPNA4,CDC42,SHC1,JAK1,PTEN,PIK3R2,STAT1,PTPN11,NCOA1,ROCK1,CREB1,STAT3,MAPK1,HRAS |
| 5.237e-05 | -9.86 | SFXN3 (sideroflexin 3) | protein interactions | 81855 | 54 | 21 | 17029 | 2761 |
TOMM20,CYLD,VDAC2,TUFM,NDUFA4,ESYT1,SRSF5,VDAC1,EDEM2,GLMP,HUWE1,TIMM17A,DNAAF2,FAM3C,PML,MPV17,ACAT1,XRCC3,CLN3,TIMM50,SPTAN1 |
| 5.250e-05 | -9.85 | DNA-directed 5'-3' RNA polymerase activity | molecular function | GO:0003899 | 41 | 17 | 17224 | 2647 |
POLR2I,POLR2G,POLR2L,PRIM2,POLR2K,POLR2D,POLR3GL,POLR3K,TWISTNB,POLR2A,PRIM1,POLR2J,CD3EAP,CRCP,RPAP1,POLR1B,ZNRD1 |
| 5.292e-05 | -9.85 | GSE9988_LPS_VS_LPS_AND_ANTI_TREM1_MONOCYTE_DN | MSigDB lists | GSE9988_LPS_VS_LPS_AND_ANTI_TREM1_MONOCYTE_DN | 167 | 45 | 17377 | 2626 |
KCTD7,TXN,GNPDA1,KLHL21,RRAGC,DCUN1D4,ATP6V1B2,RLF,RGS1,SPAG5,ANKRD28,MOAP1,DTL,SNUPN,VMP1,THAP4,RNASEK,NAA50,BRI3,FNIP2,RNF19A,RHOBTB3,TCTEX1D2,LONRF3,RB1CC1,NUDT4,TEX10,ACSL3,CAMSAP1,MAP4K3,RHOB,RHEB,NEU1,ANKRD10,SH3BP5,SCARB2,SLCO4A1,SERTAD2,ATP6V1D,CORO1C,MAFK,OGT,NRBP1,FAM83G,ZC3HC1 |
| 5.313e-05 | -9.84 | DAZAP1 (DAZ associated protein 1) | protein interactions | 26528 | 82 | 28 | 17029 | 2761 |
EWSR1,NQO1,SUZ12,DYNLL1,MDH2,RAC1,TKT,CUL3,TIA1,CUL1,BRCA1,NANS,PKM,PCBP1,ARF4,PRDX1,RPA1,CAND1,GLOD4,WWP2,RPA2,PIN1,DUT,ARF5,TAGLN2,TALDO1,PCBP2,CFL1 |
| 5.315e-05 | -9.84 | coated membrane | cellular component | GO:0048475 | 98 | 30 | 18223 | 2701 |
CHMP2A,TMED7,COPA,GGA1,SCYL1,COPE,AP3M2,TMED3,AP1B1,GGA2,AP4E1,AP3S1,PEF1,SYNRG,COPG2,PICALM,COPB2,NECAP2,SEC31A,PDCD6,CHMP4A,SAR1A,AP3S2,SEC24C,AP1M1,AP2B1,AP1S1,CHMP4B,CLTB,AP2S1 |
| 5.315e-05 | -9.84 | membrane coat | cellular component | GO:0030117 | 98 | 30 | 18223 | 2701 |
CHMP2A,TMED7,COPA,GGA1,SCYL1,COPE,AP3M2,TMED3,AP1B1,GGA2,AP4E1,AP3S1,PEF1,SYNRG,COPG2,PICALM,COPB2,NECAP2,SEC31A,PDCD6,CHMP4A,SAR1A,AP3S2,SEC24C,AP1M1,AP2B1,AP1S1,CHMP4B,CLTB,AP2S1 |
| 5.315e-05 | -9.84 | GO_ERAD_PATHWAY | MSigDB lists | GO_ERAD_PATHWAY | 70 | 24 | 17377 | 2626 |
TMUB1,ATXN3,SEC61B,ERLIN1,DNAJB2,MAN1B1,SDF2L1,SYVN1,UBQLN2,EDEM2,RHBDD1,RNF103,DNAJB9,NPLOC4,PSMC4,DERL1,ANKZF1,RNF121,DNAJC10,SEL1L,PSMC1,RNF139,RNF5,USP13 |
| 5.339e-05 | -9.84 | GO_INTRACELLULAR_SIGNAL_TRANSDUCTION | MSigDB lists | GO_INTRACELLULAR_SIGNAL_TRANSDUCTION | 1513 | 282 | 17377 | 2626 |
RAB14,TSC2,PRKCSH,TMEM109,CUL1,CCNB1,RBM4,PARK7,CALM2,PSMD1,RAB4A,FNIP2,MAST2,MOB1A,PLCL2,DNMT1,MLST8,CDC5L,PLK3,BAK1,PGAP2,RHOBTB3,NRAS,AKT2,TOPORS,MCL1,RAB22A,RAB2B,ARF4,KRIT1,MAP3K4,MKNK1,SMAD2,RPS27A,PSMD8,LIMK1,AXIN1,OGT,TFDP2,SMAD1,E2F2,ZMAT3,DDX58,WSB2,RHOC,PRKAA1,VAV2,RAB23,CYCS,PSEN1,PSMD9,CNOT3,NDUFS4,RTKN,TFAP4,DAPK1,MSH2,PIKFYVE,GNAI2,SOCS5,CYFIP1,MAPKAPK3,RB1CC1,USP10,RIT1,MAP2K2,PSMB3,RHOB,PPP3R1,CNOT6,MAP3K5,CDK2,NRBP1,ALS2,CDKN2A,RHOG,RAB11B,RAF1,RPS6KA1,RAC1,BCL2L1,PRKACA,STMN1,CRKL,MOAP1,RAB21,PRKD3,CCNA2,SHC1,SP100,ATP2A2,RALB,ADCY9,SOCS6,CDKN1B,CEP63,MAVS,TP53BP2,ARL5A,CFL1,ADCY7,SHOC2,MAP4K4,CUL3,RAB1A,ASB13,PSMB9,ERC1,TRIM28,SOCS7,PPP2CA,HINT1,JAK1,RAB24,HIPK2,STAT1,TICAM1,PPP5C,RHEBL1,DEPDC1,ZFP91,CCM2,FLOT1,BRAP,IFT27,RAB11A,FOXO3,MAD2L2,PSMD2,PDCD10,PTEN,CENPJ,ARF5,ARHGEF1,PTPN11,GTSE1,MAP3K14,CNOT6L,UBE2M,MSH6,SPTAN1,PDPK1,PPP3CA,TNFAIP3,NET1,RFXANK,RABIF,ZP3,RHOT1,MARK2,SH3BP5,GNA12,GPS2,MAPK6,TFDP1,PML,AEN,DDX5,RGL1,NPHP4,NF1,SIRT2,MAPK14,BIRC2,DLG5,RAB8A,RAP1A,PCNA,CDC42,SIVA1,RAB35,PIK3R2,AKR1B1,ASB6,CARM1,SRPK2,COPS8,RBX1,TLK1,EZR,UBE2V1,BRCA1,SOX4,RAB5B,STK17B,RHEB,E2F4,SOCS4,CAB39,ZNF268,STK11,DVL1,ROCK1,CLU,CHEK2,PSMC1,LAMTOR3,MEF2A,RACGAP1,NCKAP1,RAB6A,PPP3CB,DOCK11,RAPGEF6,APOPT1,RB1,XPA,CTR9,MDFIC,BCL2,NUDT4,PSMA1,MAP4K3,KRAS,STYXL1,DAPK3,RBM38,MASTL,PSMC4,SIAH2,MYO9A,UNC13C,WASF2,SART1,CYLD,FOXM1,RRAGC,IRF3,LYN,BCAP31,VAV1,PDK2,PSMA6,MDM2,SAR1A,F2R,HTRA2,SPSB3,DVL2,PRPF19,BIRC3,PSMA8,BTG2,RAB7A,PSMB7,SLC26A6,NFATC2,AZI2,ARL5B,TOLLIP,DNAJC10,TAB2,PSMD3,STK38,MAPK1,SMAD4,MIF,SH2D3A,ARFIP2,ARF1,MYO9B,FGFR3,TANK,ARHGEF2,ANP32A,STAT3,CAMK2G,TGFB1,PPP1R9B,RHOA,PRKDC,ARHGEF12,MEN1,RHOT2,MAPK3,RAB18,ELMO1,KBTBD7,E2F1,PKD2,HRAS,IFI16 |
| 5.362e-05 | -9.83 | LI_DCP2_BOUND_MRNA | MSigDB lists | LI_DCP2_BOUND_MRNA | 83 | 27 | 17377 | 2626 |
CHMP2A,DEAF1,PPIB,POLR2L,NQO2,UFC1,NARF,MRPL12,JMJD6,EDF1,MTX1,RFC2,EIF3G,MAP2K2,NDUFS7,RPSA,CHAF1A,C12orf10,SMC3,NDUFS8,TTC3,RUVBL2,PDXK,CYC1,PITRM1,AP2S1,EEF1D |
| 5.362e-05 | -9.83 | GO_GOLGI_ORGANIZATION | MSigDB lists | GO_GOLGI_ORGANIZATION | 83 | 27 | 17377 | 2626 |
PLK3,GCC2,GOLPH3L,GORASP1,VTI1A,COG1,RAB1A,CSNK1A1,STX16,NPLOC4,OPTN,UBXN2A,SEC23IP,PDCD10,GOLGA2,CDC42,SURF4,TMED10,VMP1,UBXN2B,MYO18A,NSFL1C,VCPIP1,YWHAZ,LMAN1,TMED2,CSNK1D |
| 5.371e-05 | -9.83 | KEGG_OOCYTE_MEIOSIS | MSigDB lists | KEGG_OOCYTE_MEIOSIS | 110 | 33 | 17377 | 2626 |
RPS6KA1,PTTG1,CUL1,PPP3CB,CCNB1,PRKACA,MAD2L2,FBXO5,CALM2,SMC3,ADCY9,ANAPC7,CAMK2G,ADCY7,PLK1,PPP3CA,RBX1,ANAPC2,PKMYT1,CDC23,MAPK3,PPP2CA,CDC16,CDC27,PPP2R5A,PPP3R1,YWHAZ,YWHAH,CCNB2,MAPK1,CDK2,ESPL1,ANAPC4 |
| 5.389e-05 | -9.83 | Bromodomain | interpro domains | IPR001487 | 42 | 17 | 18492 | 2768 |
ASH1L,BRD4,KAT2A,BAZ2A,ZMYND11,SMARCA4,PBRM1,TRIM28,ATAD2,SP100,BRPF3,BRD2,BRWD1,BAZ1B,BRD7,BRWD3,BRD9 |
| 5.390e-05 | -9.83 | skin-benign_melanocytic_nevus-Spitz | COSMIC cancer mutations | skin-benign_melanocytic_nevus-Spitz | 24 | 12 | 17385 | 2587 |
KIF5B,PWWP2A,NRAS,ZCCHC8,KRAS,ERC1,HRAS,HLA-A,CDKN2A,MYO5A,LMNA,DCTN1 |
| 5.393e-05 | -9.83 | FOXK2 (forkhead box K2) | protein interactions | 3607 | 125 | 38 | 17029 | 2761 |
NCOR2,ZBTB10,MAX,PHF23,SF3B1,THRAP3,ASXL2,ANKRD28,SAP130,TFAP4,ZNF428,RB1,NRF1,NUP107,H2AFY,CTR9,KANSL2,SAP30L,ARID4A,DVL2,SRPK2,SAP30,YTHDC1,PHF20L1,SNRNP200,FOXK1,CIC,DRAP1,SMU1,UHRF1BP1,KDM1B,CDK11A,BRMS1,GPS2,TULP3,CHEK2,SINHCAF,HDAC2 |
| 5.429e-05 | -9.82 | dolichyl-diphosphooligosaccharide-protein glycotransferase activity | molecular function | GO:0004579 | 9 | 7 | 17224 | 2647 |
RPN1,RPN2,OSTC,DDOST,MAGT1,STT3A,DAD1 |
| 5.436e-05 | -9.82 | GSE22886_UNSTIM_VS_IL2_STIM_NKCELL_UP | MSigDB lists | GSE22886_UNSTIM_VS_IL2_STIM_NKCELL_UP | 177 | 47 | 17377 | 2626 |
EXOC3,NACA,BTN3A1,IRF3,IP6K2,SUPT7L,DUSP22,FOXO3,SDHA,METTL3,FAM8A1,WDR48,ZER1,CYHR1,PRDM4,CLCN6,ZNF226,AFF1,PIK3IP1,CITED2,CTDSP2,GM2A,SPSB3,NIPSNAP1,YTHDC1,GCC2,PBXIP1,BAZ2A,PSPC1,MAN1B1,ATXN1,FRAT2,SRSF5,PTTG1IP,KDM3A,BSDC1,RHBDF2,RXRB,C19orf54,MTMR3,SGSH,STAT6,IGBP1,FAM208A,CBX4,PDCD4,N4BP2L2 |
| 5.445e-05 | -9.82 | endopeptidase complex | cellular component | GO:1905369 | 67 | 23 | 18223 | 2701 |
TXNL1,UBQLN4,PSMA8,UBXN1,PSMB7,PSMA1,PSMD9,PSMB9,PSMB3,PSMC4,RAD23A,PSMD2,PSMA6,PSMD1,IDE,PSMD8,UCHL5,PSMD3,RAD23B,UBE3C,ECPAS,PSMC1,HTRA2 |
| 5.478e-05 | -9.81 | COPG1 (coatomer protein complex subunit gamma 1) | protein interactions | 22820 | 78 | 27 | 17029 | 2761 |
TELO2,COPA,PHB2,PRKCSH,SF3B1,MAGED1,COPE,TAP1,WBP2,PMS2,TMEM216,BRCA1,ARF1,MCM2,RUFY1,COPG2,HLA-A,COPB2,SF3B2,KEAP1,SMC3,TMED10,HUWE1,ERGIC3,H2AFX,PTGES3,CDC5L |
| 5.478e-05 | -9.81 | BCAS2 (BCAS2, pre-mRNA processing factor) | protein interactions | 10286 | 78 | 27 | 17029 | 2761 |
SNRNP200,CYLD,SUZ12,SF3B6,PPIE,TRIO,RPS10,CUL1,KRAS,PRPF3,SF3A2,RPA1,DDX23,RPA2,HGS,CTNNBL1,DSN1,GOLGA2,EIF4A3,MCM5,PSMD3,EFTUD2,YJU2,POT1,CDC5L,PRPF19,SRSF10 |
| 5.478e-05 | -9.81 | GO_MITOCHONDRIAL_TRANSPORT | MSigDB lists | GO_MITOCHONDRIAL_TRANSPORT | 143 | 40 | 17377 | 2626 |
TOMM20,MTX3,DYNLL1,SLC25A12,BCL2L1,PSEN1,SLC25A37,MOAP1,TIMM23,SIVA1,FBXO7,BCL2,TP53BP2,ATF2,STAT3,MTX2,TIMM50,PPIF,BAK1,TIMM8B,MRS2,HEBP2,MTX1,TOMM40,VDAC1,RHOT1,SLC25A5,RHOT2,MFN2,STOML2,HSPA4,TIMM13,TIMM17A,TFDP1,PPP3R1,E2F1,YWHAZ,YWHAH,EYA2,SLC25A33 |
| 5.479e-05 | -9.81 | Vps4b (vacuolar protein sorting 4B) | protein interactions | 20479 | 58 | 22 | 17029 | 2761 |
CHMP2A,PDCD6IP,CDT1,FLOT1,ATP6V0A1,SLC4A2,ATP6V1B2,CHMP2B,GAR1,ZER1,DERL1,CHMP4A,NSF,TIMM23,CAPN7,STX18,SARAF,CHMP4B,RPRD1B,ATP6V0D1,GPATCH4,ATP6V1G1 |
| 5.479e-05 | -9.81 | MRPL23 (mitochondrial ribosomal protein L23) | protein interactions | 6150 | 58 | 22 | 17029 | 2761 |
RPS15,RPS2,MRPL9,MRPL42,MRPL39,TCF3,MRPL12,TUFM,ILF3,RPL8,MRPS10,NENF,MRPS14,MRPL50,MRPL2,MRPL55,COQ4,HNRNPR,MPV17,MRPL13,MRPL3,HNRNPM |
| 5.479e-05 | -9.81 | MRPS26 (mitochondrial ribosomal protein S26) | protein interactions | 64949 | 58 | 22 | 17029 | 2761 |
NOL12,NIFK,MRPL42,RBM42,MRPS15,USP42,MRPL12,RPL6,CUL3,CUL1,LMNA,CAND1,PPP2CA,HNRNPR,GRSF1,KBTBD7,MRPS27,TRMT10B,DUSP11,SNRNP70,ZC3H3,MRPL32 |
| 5.484e-05 | -9.81 | GSE2128_C57BL6_VS_NOD_THYMOCYTE_UP | MSigDB lists | GSE2128_C57BL6_VS_NOD_THYMOCYTE_UP | 182 | 48 | 17377 | 2626 |
SEPHS2,RECQL,HNRNPAB,PPP1R12A,KDM4A,B4GALT5,FAM129A,UCK2,STARD7,KIF23,CSNK2A1,MYEF2,SCYL2,MXD1,SPAG5,MBD4,LYAR,CAPN2,PA2G4,CENPJ,UCHL5,METTL14,KIF14,GTSE1,AHDC1,S100A6,ELOF1,SAP30,PSMA1,KCTD20,CDCA2,CCNF,SH3GLB1,HAUS8,GNAS,UAP1,KIF18B,NSMCE2,MRPL27,H2AFX,MEGF9,HMGB2,KPNA2,TAF12,WDR62,CDK2,LRP8,ZNF146 |
| 5.484e-05 | -9.81 | GSE22033_WT_VS_PPARG_KO_MEF_DN | MSigDB lists | GSE22033_WT_VS_PPARG_KO_MEF_DN | 182 | 48 | 17377 | 2626 |
ZNF76,ANKRD27,GLT8D1,NSMCE4A,SUMO2,KIF23,SECISBP2,GGPS1,FAM8A1,PAPOLA,FLAD1,VAV1,ZNF302,TBC1D22A,UCHL5,PIK3R2,XRCC2,MEA1,PRC1,DNM2,GLTP,TTC4,CEP63,DNAL4,TDP1,ELOVL5,PPP3CA,TK1,AGGF1,DCAF6,FAM49B,NET1,IDH3A,WDHD1,LRP5,HAGH,CHCHD3,OSBPL11,AGPAT2,PTER,CEP55,WDR59,CAB39,HMGB2,GALNT10,TMEM14A,CCDC59,S100PBP |
| 5.484e-05 | -9.81 | GSE14308_TH1_VS_NATURAL_TREG_UP | MSigDB lists | GSE14308_TH1_VS_NATURAL_TREG_UP | 182 | 48 | 17377 | 2626 |
MIB2,COMMD10,CHMP2A,KARS,NDUFV2,LZTR1,PRKCSH,MANBA,POC1A,TMEM41B,PPP1R15B,RBM8A,ARID5A,CHCHD2,JMJD6,SIRT2,ITGB5,MRPL19,ANKRD28,MED8,SUV39H2,TIMM23,MRPL34,FNIP2,DRAM2,ENPP4,TCTEX1D2,LONRF3,CDC123,SCFD2,TBRG4,KCTD20,DCTD,BICD2,RIT1,ARPC1A,LSG1,GINS4,RAD54B,AKAP1,YIF1A,MRPL55,CORO1C,HAGHL,STK11,REEP4,HRAS,UNC13C |
| 5.484e-05 | -9.81 | GSE5589_UNSTIM_VS_45MIN_LPS_AND_IL10_STIM_MACROPHAGE_DN | MSigDB lists | GSE5589_UNSTIM_VS_45MIN_LPS_AND_IL10_STIM_MACROPHAGE_DN | 182 | 48 | 17377 | 2626 |
KCTD7,TOMM20,TRIM11,MRI1,PTTG1,NUP54,COX4I1,THRAP3,GGPS1,VPS25,UBLCP1,DUS4L,PIK3R2,C8orf59,MRPL11,MYBL1,SGCB,GINS1,B3GALT6,EID1,C16orf72,TLK1,WDHD1,NDUFA7,OGDH,EIF4G2,FKBP3,SFXN5,RHOB,CLNS1A,PSMC4,PPP2CA,NAP1L1,KPNA4,PCM1,STT3A,HNRNPR,SETD3,NRM,COX5A,MDH1,SCARB1,ATP6V1C1,TMEM14A,SLC25A39,VPS29,SVIP,FAM72A |
| 5.484e-05 | -9.81 | GSE21379_TFH_VS_NON_TFH_SAP_KO_CD4_TCELL_UP | MSigDB lists | GSE21379_TFH_VS_NON_TFH_SAP_KO_CD4_TCELL_UP | 182 | 48 | 17377 | 2626 |
GCLM,RECQL,ABCA3,PLXNC1,ADD1,NQO1,DHX9,ABCB10,PXMP2,PPP3CB,COMMD5,BLM,UBLCP1,CDKN2C,GOLM1,RB1,APLP2,STRBP,HDAC7,ATP13A3,TPST1,RNF19A,MINPP1,PIKFYVE,ELL2,BTAF1,NOL8,CPOX,NARF,UTP15,PIP4K2C,TBRG4,PRKRA,HAGH,MTR,SH3GLB1,USP36,TWISTNB,OPTN,EPB41,NECAP2,PEX5,PDLIM1,ACYP1,DUSP11,FAM126A,TFDP2,ZMAT3 |
| 5.484e-05 | -9.81 | GSE17721_12H_VS_24H_LPS_BMDC_DN | MSigDB lists | GSE17721_12H_VS_24H_LPS_BMDC_DN | 182 | 48 | 17377 | 2626 |
MRPL9,IVNS1ABP,MRPS2,UFC1,HEXB,TMEM97,NDUFA4,GTF3A,BRIX1,CDK11B,MAPK14,POLR3K,MRPL19,HMG20A,DDRGK1,SEC11A,LHX8,ADCY9,PPCDC,KDELR1,CSTF1,TDP1,FTL,FOPNL,BTG2,PSPC1,METTL5,LRBA,TEX10,GLO1,TMEM147,WBP1,TSR2,RDH11,GLOD4,CAT,TIMM13,CDC16,ACOX1,COX7A2L,LRPPRC,FTSJ1,SLC16A1,DTD1,FAU,OAZ1,POT1,TMEM33 |
| 5.484e-05 | -9.81 | GSE9509_10MIN_VS_30MIN_LPS_STIM_IL10_KO_MACROPHAGE_UP | MSigDB lists | GSE9509_10MIN_VS_30MIN_LPS_STIM_IL10_KO_MACROPHAGE_UP | 182 | 48 | 17377 | 2626 |
NCOR2,ANKRD27,SUCLG1,POLR2K,HEXB,ACAP1,ASAH1,EBNA1BP2,MAN2B1,COMMD8,PARK7,APLP2,EIF2S2,NUP210,EXOSC7,DAD1,ANXA5,RPN2,MRPL48,RNF135,ALDH18A1,TOP1MT,C12orf75,TNRC18,PPA1,TMED2,S100A6,IMPA2,CFL1,TIMM50,EIF5A,MAPKAPK3,CDC123,LAP3,KRTCAP2,TXNL4A,FAS,SDHB,QARS,CORO1C,MRPL27,PTPN7,PGRMC1,CTSA,TMEM159,VPS29,STARD3NL,ZNF511 |
| 5.484e-05 | -9.81 | GSE3720_VD1_VS_VD2_GAMMADELTA_TCELL_WITH_LPS_STIM_DN | MSigDB lists | GSE3720_VD1_VS_VD2_GAMMADELTA_TCELL_WITH_LPS_STIM_DN | 182 | 48 | 17377 | 2626 |
SEPHS2,PDCD6IP,CKLF,KDM4A,FAM129A,CUTA,HEXB,MON1B,STARD7,KIF23,DNAJB1,SLC20A1,ETS1,STMN1,FOXO3,CMTM6,RAD23A,DDRGK1,EBP,CAPN2,NFATC3,CLIC4,ZNF335,ARHGEF2,AHDC1,SGCB,DNMT1,CAMK2G,KCNAB2,TACC3,CDKN2AIP,USO1,TRAFD1,RBM42,BTG2,IDH3A,EMP3,PKMYT1,MARK2,MYO1F,PEX5,PPP2R5A,CEP55,PPM1G,MEGF9,MLYCD,EHD4,IGBP1 |
| 5.484e-05 | -9.81 | KRIEG_KDM3A_TARGETS_NOT_HYPOXIA | MSigDB lists | KRIEG_KDM3A_TARGETS_NOT_HYPOXIA | 182 | 48 | 17377 | 2626 |
NDUFA5,MTX3,TMBIM4,FAM129A,C16orf87,SLC25A12,MIEN1,METTL3,ANKRD39,ATPAF1,MAT2B,PTPN2,FANCL,CDC42,ZNHIT6,CAPZA1,SRI,ZNF226,LDLRAD3,HDHD2,ACSL5,METTL1,TCTEX1D2,NOL8,HSDL1,TMEM216,POLR3GL,MRPL16,GLO1,EIF2A,THNSL1,CLNS1A,HMGN2,GOLGA4,CHMP4A,WDR4,STAT1,WDR7,PGRMC1,RNF38,AP1S1,FKBP5,BTBD10,ZMIZ1,PDCD2L,N4BP2L2,NUDT3,USP13 |
| 5.484e-05 | -9.81 | GSE27786_LIN_NEG_VS_BCELL_UP | MSigDB lists | GSE27786_LIN_NEG_VS_BCELL_UP | 182 | 48 | 17377 | 2626 |
TMEM106C,TM9SF4,PDAP1,ANKH,TRMT6,MOGS,NENF,LANCL1,TMEM69,ZBTB45,IL6ST,INTS1,PRC1,GTSE1,FNIP2,RPN2,UBE3B,ALDH18A1,TTLL12,RPRD1B,PPA1,FAM171A1,ACSL5,UBQLN4,DDX28,TCTEX1D2,SIGMAR1,RAD51AP1,MRS2,LDB1,ACSL3,CCDC34,NUP155,CCNF,BORA,API5,CCT8,OPTN,EPB41,PCM1,RBL1,DBI,WDR62,C11orf1,LRP8,MRPL3,GCSH,PTOV1 |
| 5.492e-05 | -9.81 | establishment of protein localization to endoplasmic reticulum | biological process | GO:0072599 | 105 | 32 | 17256 | 2622 |
SRP72,RPL29,RPS15,SEC61B,RPL35,RPS2,RPLP2,SEC61G,RPL6,RPS10,RPL38,RPL8,RPL15,RPS24,RPL27A,RPS9,RPSA,RPL23A,RPL36,RPL11,RPL37,CHMP4A,RPL32,SEC61A1,RPL17,RPS27A,RPS14,RPLP1,RPL19,CHMP4B,SPCS3,RPS26 |
| 5.493e-05 | -9.81 | MTNR1B (melatonin receptor 1B) | protein interactions | 4544 | 134 | 40 | 17029 | 2761 |
TRIP12,COPA,THOC1,ANXA6,BCL2L1,UBQLN2,AP1B1,GNB2,FANCI,EBP,DST,FAM192A,ATP6V0B,SMC3,INTS1,CLDND1,PDIA6,GNAI2,PPP6R1,USP34,UBQLN4,FTL,HARS,PRKDC,PPP1R21,CUL3,MTMR6,KMT2C,AP4E1,MACF1,EIF3A,BTBD1,GNAS,CDC16,PSMD8,PPM1G,TMEM14A,ESPL1,IPO4,SMARCD1 |
| 5.515e-05 | -9.81 | GSE2585_AIRE_KO_VS_WT_CD80_HIGH_MTEC_UP | MSigDB lists | GSE2585_AIRE_KO_VS_WT_CD80_HIGH_MTEC_UP | 187 | 49 | 17377 | 2626 |
RAB14,PKP4,TM9SF4,FOXM1,B4GALT5,WDR13,TRIO,FAM76A,RMI2,CBLL1,KLF13,GLUD1,ZNRF3,GYG1,DUSP22,TCF19,PAIP1,TFAP4,CAPN2,PRKD3,ZNF449,PPP1R8,FIZ1,ARHGEF1,ZCCHC2,PPP1R12C,FNIP2,TTC3,BCAP29,STRAP,WDR41,PSMB7,LRRC8A,RAB1A,ALG3,TMEM41A,TONSL,MFAP1,FASTK,SIAH2,ZNF436,PDXK,IDH3B,USF2,RPS6KC1,TSPAN5,ZC3HAV1,RAB3IL1,VPS29 |
| 5.515e-05 | -9.81 | GSE42021_CD24HI_VS_CD24INT_TREG_THYMUS_UP | MSigDB lists | GSE42021_CD24HI_VS_CD24INT_TREG_THYMUS_UP | 187 | 49 | 17377 | 2626 |
WSB2,RAC1,KIAA0232,TMX4,RBM8A,TRIO,CERK,ASAH1,NIT2,GTF3A,PLXNA1,PDXDC1,WRB,EBP,ANKRD28,CAPN2,INPP5A,PIN1,SRI,FBXW2,TTC3,MAVS,MRPL48,TPCN1,FAM171A1,PDLIM2,USP34,VOPP1,MYBL2,USP22,ARPC1A,NDRG3,HAGH,EIF4G2,AMZ2,AHNAK,TMEM168,JAK1,FASTK,COX7A2L,APPL2,IMPDH1,PITPNA,GALNT10,PREPL,CCNB2,PTDSS1,DDB1,USP13 |
| 5.515e-05 | -9.81 | GSE19401_RETINOIC_ACID_VS_RETINOIC_ACID_AND_PAM2CSK4_STIM_FOLLICULAR_DC_DN | MSigDB lists | GSE19401_RETINOIC_ACID_VS_RETINOIC_ACID_AND_PAM2CSK4_STIM_FOLLICULAR_DC_DN | 187 | 49 | 17377 | 2626 |
SART1,ANKRD27,GLT8D1,FOXM1,IRF3,TMED3,STMN1,SYNRG,METTL3,POFUT1,YY1AP1,SAC3D1,CHKA,MZT2A,DBNDD1,MRPL34,OSTF1,PCBP2,MICAL3,MSH6,TACC3,KDM3B,CPNE1,ZDHHC18,MIOS,SELPLG,KIAA0930,SEPT8,MRPL16,UBE4B,PPFIA3,BICD2,VDAC1,CCNF,EIF4H,USP21,ZDHHC3,PRDM11,PSMC4,GLOD4,MYO1F,TRAM2,PDCD6,E2F1,AEN,ZNF268,TCOF1,PPP6R3,RTN3 |
| 5.515e-05 | -9.81 | GSE42088_UNINF_VS_LEISHMANIA_INF_DC_4H_UP | MSigDB lists | GSE42088_UNINF_VS_LEISHMANIA_INF_DC_4H_UP | 187 | 49 | 17377 | 2626 |
WSB2,KCTD7,GCLM,TXN,NUP188,PARP12,ST13,NQO1,UGP2,AGRN,TRIP10,FAM129A,SDC2,CREBL2,TBC1D13,NENF,PLXNA1,METTL3,PIP5K1C,CD59,TNS3,PSMD1,CLIC4,PPME1,BDH1,AKR1B1,MTX2,CARM1,ABCC1,USO1,ATP2C1,ATXN1,DNAJA1,EDEM2,NEU1,PRDX1,NMT2,MAP3K4,KEAP1,TWSG1,LIMK1,BAZ1B,ST3GAL2,RGL1,PPP6R2,CD81,LRP8,NRBP1,TUBB |
| 5.515e-05 | -9.81 | GSE17721_CTRL_VS_CPG_2H_BMDC_UP | MSigDB lists | GSE17721_CTRL_VS_CPG_2H_BMDC_UP | 187 | 49 | 17377 | 2626 |
TOMM20,NSMCE4A,ADD1,CASP6,TRIM11,ZFP91,UBXN1,CDIPT,LCLAT1,EXT2,RRP36,C14orf119,ANKRD28,KRI1,AKAP8,BDH1,ABCD1,TAF5L,BCAP29,TTC4,CNOT6L,TMEM14C,NAA35,SAP30L,FRMD8,NSUN4,CAMK2G,POC5,MED22,DRAM2,KLF10,FOPNL,KAT7,TUBGCP5,DNAJC9,ARID1A,SMC2,BTBD1,CCDC127,ANKRD10,HHEX,HSPBP1,OSBPL11,PPP2R5A,LUC7L3,MLYCD,NANP,CSNK1D,STARD3NL |
| 5.515e-05 | -9.81 | GSE23502_BM_VS_COLON_TUMOR_HDC_KO_MYELOID_DERIVED_SUPPRESSOR_CELL_DN | MSigDB lists | GSE23502_BM_VS_COLON_TUMOR_HDC_KO_MYELOID_DERIVED_SUPPRESSOR_CELL_DN | 187 | 49 | 17377 | 2626 |
RHOG,IER2,NAT9,PKP4,GPR132,SLC41A1,ANKH,GLUD1,NENF,GTF3A,MXD4,PMVK,MAPK14,APOPT1,LMNA,IL6ST,TBC1D14,POP7,PPCDC,TTC4,TAGLN2,TECR,SAP30L,ZNF189,TGFB1,TIMM8B,TIMP2,RFC3,SEPT9,PBXIP1,BTG2,RFXANK,MAP7D1,CYB5A,RHBDF2,SCARB2,TRAM2,TPD52L2,ZNF282,IDE,C1orf131,PDLIM1,LPCAT4,SEL1L,GPI,PREPL,E2F2,C11orf1,ZMAT3 |
| 5.515e-05 | -9.81 | GSE17721_POLYIC_VS_GARDIQUIMOD_1H_BMDC_DN | MSigDB lists | GSE17721_POLYIC_VS_GARDIQUIMOD_1H_BMDC_DN | 187 | 49 | 17377 | 2626 |
TMED7,ANXA6,CASP6,MRPS2,ACTR3,CHIC2,ABCB10,NIT2,XPO7,DUSP22,PRKACA,RHBDD1,RNF103,XPR1,SEC11A,ATP6V0B,PRKD3,SNX18,SOCS6,RPF2,MDFIC,TMEM14C,TPCN1,PTPN18,PRIM2,SEPT9,NCK1,IDH3A,RAD51AP1,EMB,KRAS,DCUN1D5,STK17B,RHOB,PLEKHF2,RPA1,MKNK1,ETS2,ACYP1,VPS26B,OAZ2,TFDP1,ACLY,PIAS2,MAPK1,YWHAH,POT1,NUMB,TMEM33 |
| 5.515e-05 | -9.81 | GSE15930_STIM_VS_STIM_AND_IFNAB_48H_CD8_T_CELL_UP | MSigDB lists | GSE15930_STIM_VS_STIM_AND_IFNAB_48H_CD8_T_CELL_UP | 187 | 49 | 17377 | 2626 |
RMND5A,GMFG,ADD1,CASP6,DAP,CDCA8,POMP,TWF2,MAP1LC3B,STMN1,PIP4K2A,XPR1,CSDE1,MCM5,PHTF1,BUD31,ANXA5,CDKN1B,CNN2,RNF26,FRMD8,CTDSP2,PDCL3,HNRNPM,KDELR1,CSNK1G2,AKT2,RAD51AP1,ITM2A,ARHGDIB,MCM2,KIF11,ASF1B,BTBD1,RBM38,RPA1,EIF3K,PLD3,NUCB1,NAP1L1,PDLIM1,PDRG1,HNRNPH3,COX7A2L,OAZ2,PQBP1,CTSA,CDK2,S100PBP |
| 5.532e-05 | -9.80 | GSE360_L_DONOVANI_VS_B_MALAYI_LOW_DOSE_MAC_UP | MSigDB lists | GSE360_L_DONOVANI_VS_B_MALAYI_LOW_DOSE_MAC_UP | 192 | 50 | 17377 | 2626 |
TXN,MPHOSPH8,SEC61G,RHOC,SUMO2,OAT,PARN,PDXDC1,SEC11A,CD59,ADD3,DNAJC8,HUWE1,BANF1,KIFAP3,MDFIC,NUP153,CRY2,TP53BP2,STAT3,GM2A,CLPTM1,SP3,TXNL1,NASP,ELL2,IDH3A,MKI67,LDHA,MTMR6,PRPF3,MCFD2,PRPSAP1,ANKRD46,EIF3A,SH3BP5,PPP2R5A,ERGIC3,CAPN7,MAPK6,PGRMC1,E2F1,PPP1R11,BAZ1B,NCOA1,PDLIM5,TAF6,ATP6V0E1,TUBB,DDB1 |
| 5.532e-05 | -9.80 | GSE8685_IL2_STARVED_VS_IL2_ACT_IL2_STARVED_CD4_TCELL_DN | MSigDB lists | GSE8685_IL2_STARVED_VS_IL2_ACT_IL2_STARVED_CD4_TCELL_DN | 192 | 50 | 17377 | 2626 |
SEPHS2,POLA2,GCLM,SKA3,DEPDC1,SCOC,TKT,RRM1,DHX9,RACGAP1,SDF2L1,SPAG5,KRR1,RFWD3,SLC31A1,CCNA2,UBE2Q2,GOT2,FUT8,PARL,TIMELESS,H2AFY,KIFAP3,CENPM,DNMT1,PRIM2,IDH3A,OAF,ERLIN1,ZBED5,CCDC34,CKAP2L,CDCA2,GORASP2,EIF4H,API5,TWISTNB,ASF1B,RAD54B,DTWD1,PCM1,ZNF330,TOMM6,LUC7L3,DBI,ADAM9,KPNA2,USP11,OAZ1,CCDC137 |
| 5.532e-05 | -9.80 | GSE360_LOW_DOSE_B_MALAYI_VS_M_TUBERCULOSIS_MAC_UP | MSigDB lists | GSE360_LOW_DOSE_B_MALAYI_VS_M_TUBERCULOSIS_MAC_UP | 192 | 50 | 17377 | 2626 |
NCOR2,NUP188,HNRNPAB,ADD1,RPS6KA1,TCF3,MAGED1,ADO,BCL2L1,CDIPT,BECN1,ITGB5,ABHD14A,USP5,SF3B2,MOAP1,VAV1,FARSA,NDUFV1,SHC1,SYNM,DUS4L,SIAH1,ARF5,KIF13B,RAB4A,CDC25B,CYB5R1,NAP1L4,CREB1,PACS2,EEF1D,MAPRE2,TSTA3,TACC1,EMP3,DIDO1,PPWD1,NUTF2,MAK16,CDK11A,RHEB,UBTF,DUSP3,E2F4,PLOD3,CLN3,LTA4H,AP2S1,HDAC2 |
| 5.532e-05 | -9.80 | GSE24726_WT_VS_E2-2_KO_PDC_DAY6_POST_DELETION_DN | MSigDB lists | GSE24726_WT_VS_E2-2_KO_PDC_DAY6_POST_DELETION_DN | 192 | 50 | 17377 | 2626 |
MIB2,TCF12,CYTIP,CDS2,RAB11B,UBN1,FAM129A,ANKH,MEF2A,MAN2B1,MXD4,MAP1LC3B,APH1B,FBXO3,RABGAP1L,KIF13B,PHF14,LPIN2,RCSD1,SOCS6,KIFAP3,CNN2,SPTSSA,CITED2,SGCB,MGAT5,TMEM9,TPCN1,ADCY7,PPP3CA,ARHGAP17,PTPN18,MAPRE2,NUDT4,MIER1,WIPF1,POLR3GL,FXR1,POLG2,ARF4,RXRB,TRIM47,SNAP23,KBTBD7,NCOA1,TFDP2,C11orf1,PDLIM5,RAB3IL1,PDCD4 |
| 5.558e-05 | -9.80 | UBQ-conjugating_enzyme/RWD | interpro domains | IPR016135 | 54 | 20 | 18492 | 2768 |
UBE2D3,UBE2E2,RWDD1,RNF25,UFC1,UBE2Q1,UBE2Z,UBE2V1,KRAS,EIF2AK4,UBE2I,FANCL,UBE2Q2,UEVLD,WDR59,RWDD4,RNF14,UBE2C,UBE2M,UBE2QL1 |
| 5.602e-05 | -9.79 | KLHL20 (kelch like family member 20) | protein interactions | 27252 | 74 | 26 | 17029 | 2761 |
CTU2,CORO7,RHOA,PRIM2,MIOS,KRBA1,IVNS1ABP,CUL3,ADSL,ARHGEF12,HDGFL2,GFER,PICALM,PRIM1,OSBPL11,EIF2S2,KLHL20,PIN1,PML,DAPK1,ATXN2L,TCEA1,COPS6,UBE2M,RPRD1B,LUC7L2 |
| 5.616e-05 | -9.79 | extracellular exosome | cellular component | GO:0070062 | 2118 | 375 | 18223 | 2701 |
RAB14,TXN,PDCD6IP,H2AFZ,LUZP1,ADAM10,HEXB,TMEM109,NANS,PLXNA1,PARK7,RPL23A,NAPG,PA2G4,RAB4A,AP1M1,DNM2,SLC26A2,MOB1A,MGAT5,PCBP2,RHOBTB3,NRAS,GNG7,SMC2,NUTF2,GALNT7,RAB22A,RAB2B,ARF4,AHNAK,WAS,RPS27A,RPS14,PTER,PRDX5,ITGB1,ATP6V0C,PFKP,ANXA11,SVIP,PPIB,HSPH1,HLA-E,RHOC,CUTA,B4GALT1,MAN2B1,ITGB5,VPS25,MYL6B,GNS,CD59,ARPC5,SNX18,MEGF8,ATIC,GEMIN4,MVP,GNAI2,PABPC1,PPA1,CYFIP1,FTL,CPQ,PRRC2A,WDR1,PIP4K2C,ITM2A,EXOSC9,PLEC,CAPZA2,PKM,PTTG1IP,CYFIP2,CCT8,RHOB,PSMB3,FAS,CAT,ADSS,PTPRF,SCARB2,TXNDC16,CSK,RBMX,ACLY,APPL2,MDH1,GPI,CFAP20,HEXA,RHOG,RAB11B,TRIP10,RAC1,ACTR3,OLA1,MYH9,NIT2,PRKACA,SAFB2,STMN1,CPNE3,APP,GNB2,RAB21,APLP2,AHCTF1,RALB,DUT,TALDO1,GPD1L,TMBIM1,CFL1,ATP6V1G1,GPX4,CPNE1,ENPP4,CCT2,TAOK1,CUL3,ATP6V0A1,DNAJA1,GSTCD,RAB1A,PSMB9,H2AFV,PPP2CA,CHCHD3,ALDH3B1,HSPA4,HINT1,H2AFX,PDXK,B4GALT3,TUBB,GALK1,RPS2,SCAMP3,ANXA6,FLOT1,TKT,ABHD14B,ATP5F1B,SPR,PMVK,RAB11A,TUT4,WWP2,MAT2B,CAPN2,PSMD2,PDCD10,CLIC4,ITGB8,HUWE1,AHSA1,ARF5,FUT8,NAA50,ANXA5,TAGLN2,S100A6,HNRNPM,LYPLA2,SPTAN1,LDHB,STAU1,TNFAIP3,STRIP1,PARP4,LDHA,HEBP2,ECH1,PRDX1,PLD3,NUCB1,SGSH,HGS,WNT5B,DBI,CAPN7,FAM3C,NAXE,LY75,ASNA1,DDX5,PSAP,CD81,YWHAH,DDB1,UBL3,ST13,COPA,AGRN,GNPDA1,FAM129A,MOGS,SND1,TAF6L,PRNP,RAB8A,PCNA,RAP1A,CDC42,GOT2,RAB35,IL6ST,ZNHIT6,DPYSL2,SLC44A1,SRI,AKR1B1,RP2,CARMIL1,CDC37,COPS8,LAP3,MBLAC2,CYSTM1,EZR,ARHGDIB,UBE2V1,RAB5B,RHEB,UEVLD,NAGLU,CAB39,ADAM9,ARRDC1,ACTB,STK11,CLU,VPS4A,RPS26,MYL12B,CAPN1,UBE2D3,UFC1,LAMTOR3,CIB1,ASAH1,RACGAP1,DNAJB1,NCKAP1,THRAP3,RAB6A,EPHX2,SUB1,VASP,CAPZA1,YBX1,AHCY,TMEM8A,SLC12A2,HDHD2,ATP6V0D1,ABCC1,ALDH9A1,TSTA3,CREG1,NQO2,GBA,PSMA1,SEPT7,ARPC1A,APPL1,CAND1,GNAS,GOLGA4,SNAP23,SLC16A1,YWHAZ,DNPH1,CTSA,PITPNA,RUVBL2,ATP5F1A,EHD4,N4BP2L2,WASF2,CHMP2A,UGP2,RPLP2,MDH2,SLC2A1,ATP6V1B2,LYN,PCBP1,TWF2,EXT2,RPL11,HNRNPA2B1,NRF1,PSMA6,IARS,CS,PDCD2,CORO1A,CYB5R1,MINPP1,AHCYL1,LMAN1,PDIA6,ABI1,GM2A,CHP1,PSMA8,PPT1,RAB7A,BTG2,GLO1,VDAC1,CHMP2B,TOLLIP,PEF1,RPS9,RPSA,EIF3H,GLOD4,ATP1A1,PSMD3,CANT1,CHMP4B,FKBP5,SCARB1,H3F3A,SMURF1,LTA4H,CHID1,MIF,KIF3B,TOR3A,DCTN2,AGO2,ARF1,SLC12A9,DNAJB9,TFRC,MAN1A1,SPPL2A,FERMT3,GSTK1,GART,SLC1A4,H2AFY,FBL,MYO5A,SLC25A1,RHOA,ACP2,FAM49B,CSRP1,TUFM,ARHGEF12,NDRG3,NEU1,TARS,DDX23,HSPA1B,CTSL,ATP6V1D,PDCD6,ATAD2,GOLGA7,PLAA,GLG1,ACAT1,PKD2,ATP6V1C1,PLOD3,ARHGAP23,PGAM1,SAT2 |
| 5.664e-05 | -9.78 | GSE13522_CTRL_VS_T_CRUZI_Y_STRAIN_INF_SKIN_IFNG_KO_UP | MSigDB lists | GSE13522_CTRL_VS_T_CRUZI_Y_STRAIN_INF_SKIN_IFNG_KO_UP | 148 | 41 | 17377 | 2626 |
MIF,SLC30A9,SNX27,MMACHC,PPP1R2,PPP1R15B,VAV2,PCBP1,PDXDC1,ABHD14A,TPST1,RPN2,GEMIN4,MTPN,RPRD1B,LYPLA2,PLK3,EIF5A,EIF3L,BIRC3,WDR18,CYP20A1,UTP15,TBRG4,SSR2,NUP155,EXOSC9,OGFR,RAB2B,ABHD5,XRCC5,HSPBP1,DDOST,DUSP3,NSMCE2,ERGIC3,ZC3H7B,KHSRP,TMEM14A,GCSH,SLC25A33 |
| 5.675e-05 | -9.78 | ZFYVE19 (zinc finger FYVE-type containing 19) | protein interactions | 84936 | 43 | 18 | 17029 | 2761 |
UNK,UBQLN4,UFC1,UBXN1,LAGE3,UBE4B,UBQLN2,ATP6V1B2,SEC24C,TTC9C,PRDX5,CAPN7,YWHAZ,VPS4A,AHCYL1,UBE2C,IGBP1,USP34 |
| 5.675e-05 | -9.78 | GRWD1 (glutamate rich WD repeat containing 1) | protein interactions | 83743 | 43 | 18 | 17029 | 2761 |
BCCIP,EWSR1,DDX24,KMT2E,VHL,CDT1,CUL3,GTPBP4,CUL1,WDR5,CCNB1,RPL11,CAND1,DOT1L,DDX56,NOC2L,DDB1,IFI16 |
| 5.675e-05 | -9.78 | MRPL17 (mitochondrial ribosomal protein L17) | protein interactions | 63875 | 43 | 18 | 17029 | 2761 |
DDX28,MRPL9,CYLD,MRPL42,PHB2,MRPL39,MRPL12,TUFM,ILF3,NFATC2,MRPL50,MRPL2,UBA5,MPV17,MRPL13,ZC3H3,MRPL3,ABCC1 |
| 5.675e-05 | -9.78 | CFL2 (cofilin 2) | protein interactions | 1073 | 43 | 18 | 17029 | 2761 |
ST13,WDR1,MEMO1,LDHA,MYH9,CAPZA2,CAT,LIMK1,MCM5,MYO18A,AKR1B1,ACTB,STK11,CD81,POT1,PPA1,CFL1,LDHB |
| 5.675e-05 | -9.78 | PUS7 (pseudouridylate synthase 7) | protein interactions | 54517 | 43 | 18 | 17029 | 2761 |
HSPH1,EWSR1,POLR2G,NSUN2,RBM8A,POLR2D,GAR1,DHX15,CXXC4,IDE,DHX16,MCM5,DPYSL2,CTPS1,FBL,STAT3,NMD3,BYSL |
| 5.676e-05 | -9.78 | AATF (apoptosis antagonizing transcription factor) | protein interactions | 26574 | 70 | 25 | 17029 | 2761 |
LZTR1,RPS2,MAGED1,EBNA1BP2,PAWR,DAZAP2,BRIX1,DAPK3,CAND1,KRR1,KRI1,RB1,DDX56,MDM2,POLR2J,RBL1,PIN1,HIPK2,TBL3,NOC2L,RPF2,SS18L1,CHEK2,IFI16,DDX52 |
| 5.676e-05 | -9.78 | MPG (N-methylpurine DNA glycosylase) | protein interactions | 4350 | 70 | 25 | 17029 | 2761 |
SART1,PRPF38B,RACGAP1,EXOSC9,EIF2A,PKM,APP,TWISTNB,PRDX1,SRSF1,RPA1,RAD23A,PRNP,TERF2IP,KIFC1,RPA2,KDM2A,GOT2,RAD23B,NOC2L,UHRF2,CAPZA1,KHSRP,LRRC59,CSTF1 |
| 5.687e-05 | -9.77 | BRAF (B-Raf proto-oncogene, serine/threonine kinase) | protein interactions | 673 | 66 | 24 | 17029 | 2761 |
CYLD,NRAS,VHL,RAF1,BRAP,KRAS,PRKACA,MAP2K2,RHEB,MAPK3,OIP5,RAP1A,FNTA,PTEN,LIMK1,YWHAZ,FNIP2,YWHAH,MAPK1,HRAS,TERF1,HDAC2,TIMM50,CDC37 |
| 5.687e-05 | -9.77 | SEC24C (SEC24 homolog C, COPII coat complex component) | protein interactions | 9632 | 66 | 24 | 17029 | 2761 |
NDUFS1,EWSR1,COPA,CUL3,WIPF1,BRCA1,NOTCH2,XPO7,ATP6V1B2,SEC16A,APP,PICALM,CLNS1A,CAND1,CSDE1,PSMD1,CDC42,MED15,FBXO7,GTSE1,AP2B1,AHCYL1,SSRP1,CDC5L |
| 5.718e-05 | -9.77 | SFN (stratifin) | protein interactions | 2810 | 266 | 68 | 17029 | 2761 |
TSC2,WDYHV1,RAF1,CSNK2A1,RPL23A,APLP2,MDM2,SRSF4,NSFL1C,TARDBP,CDC25B,CHTOP,ATF2,LRRC59,CCAR1,SRSF10,RPL35,RPL38,UBE2V1,MCM2,SHCBP1,EIF3G,TRIM28,RPS9,DHX15,RPSA,EIF3H,PLEKHF2,SRSF1,SUPT16H,TBL3,TRIM32,COPS6,PARD3,PTOV1,PPIB,RPS2,SH2D3A,PPP1R2,RAE1,FAM53C,KIF23,KLC1,RACGAP1,CDC73,KIF5B,DTL,PTPN2,SUB1,RPL17,HDAC7,PABPC1,HNRNPM,LUC7L2,TXNL1,KIAA0930,RPL8,PLEC,RAB3IP,RPL27A,MARK2,SNRPA,ISG15,RBM25,DDX5,YWHAZ,MAP3K5,IGBP1 |
| 5.734e-05 | -9.77 | ARGLU1 (arginine and glutamate rich 1) | protein interactions | 55082 | 29 | 14 | 17029 | 2761 |
SRSF11,NIFK,SUB1,ZCCHC10,EWSR1,CHERP,JMJD6,ARGLU1,SNRNP70,CDK2,APP,SF3A2,CDC5L,SRPK2 |
| 5.734e-05 | -9.77 | PCLAF (PCNA clamp associated factor) | protein interactions | 9768 | 29 | 14 | 17029 | 2761 |
YTHDC1,METTL1,SART1,PCNA,NDUFA2,HARS,CAST,PARG,RRBP1,BUD31,KRAS,BRCA1,NDUFA7,DNMT1 |
| 5.734e-05 | -9.77 | ERGIC1 (endoplasmic reticulum-golgi intermediate compartment 1) | protein interactions | 57222 | 29 | 14 | 17029 | 2761 |
RPA2,NDUFV1,SUZ12,ERGIC3,RDH10,CTR9,PRPF4,TFG,MRPL11,GNAI2,DUSP22,MRPL32,TMED2,RPA1 |
| 5.734e-05 | -9.77 | THG1L (tRNA-histidine guanylyltransferase 1 like) | protein interactions | 54974 | 29 | 14 | 17029 | 2761 |
TPD52L2,ZNF524,TP53RK,HARS,NSUN2,PRKAR1B,SH3GLB2,CHCHD2,RANGAP1,ARPC1A,MTR,TERF1,SH3GLB1,EEF2K |
| 5.734e-05 | -9.77 | PEF1 (penta-EF-hand domain containing 1) | protein interactions | 553115 | 29 | 14 | 17029 | 2761 |
HGS,PDCD6IP,EWSR1,PDCD6,KIAA0930,CEP55,H2AFX,CUL3,LAMTOR3,SUCLG2,GPI,DAZAP2,TFG,ANXA11 |
| 5.742e-05 | -9.77 | RB_DN.V1_UP | MSigDB lists | RB_DN.V1_UP | 129 | 37 | 17377 | 2626 |
IER2,GCLM,PRKAB1,PMS2,LAGE3,UCK1,NANS,SLC35B2,IFT27,STMN1,HEATR5B,PDXP,MDM2,PCNA,SIVA1,EI24,TIMELESS,AHCY,MCMBP,CLN6,DNMT1,PCBP2,MSH6,NXT1,RFC3,BTG2,MAN1B1,DNAJC9,SLBP,RRM2,PRIM1,RPA1,RAD51C,TMEM54,DSN1,BAZ1B,AAAS |
| 5.812e-05 | -9.75 | WD40_repeat_dom | interpro domains | IPR017986 | 240 | 59 | 18492 | 2768 |
WSB2,CORO7,CDC40,COPA,TRAF7,RAE1,WDR13,POC1A,WDTC1,STRN4,WDR5,GNB2,WDR48,COPB2,DTL,WDR44,UTP18,FBXW2,TAF5L,CORO1A,UTP4,STRAP,SEH1L,CSTF1,WDR41,PRPF19,MLST8,PREB,DCAF6,WDR1,DCAF8,WDR18,SMU1,UTP15,WDHD1,WDR82,WDR81,PPWD1,ARPC1A,EML4,GEMIN5,SEC31A,PLAA,BRWD1,SCAP,TBL3,CORO1C,WDR59,WDR4,DCAF11,WDR7,PRPF4,DMWD,RBBP4,WDR91,WDR62,BRWD3,DCAF5,AAAS |
| 5.820e-05 | -9.75 | Activation of the pre-replicative complex | REACTOME pathways | R-HSA-68962 | 32 | 15 | 10287 | 1696 |
POLA2,RPA2,MCM10,POLE,PRIM2,MCM5,CDT1,DBF4,CDC6,ORC1,MCM2,ORC3,CDK2,RPA1,PRIM1 |
| 5.828e-05 | -9.75 | GO_CHROMOSOME_TELOMERIC_REGION | MSigDB lists | GO_CHROMOSOME_TELOMERIC_REGION | 153 | 42 | 17377 | 2626 |
NSMCE4A,THOC1,SMC6,SIRT2,ORC1,BLM,CDC73,WRNIP1,TERF2IP,RPA2,PCNA,SP100,MCM5,MSH2,H2AFY,PTGES3,ORC3,TERF2,TELO2,ERCC1,PRKDC,WDR82,DCLRE1C,MEN1,MCM2,GAR1,XRCC5,CBX3,RPA1,UPF1,NSMCE2,H2AFX,PML,XRCC3,CHEK2,H3F3A,CDK2,PURA,POT1,TERF1,RAD51D,DDB1 |
| 5.828e-05 | -9.75 | GSE12003_4D_VS_8D_CULTURE_BM_PROGENITOR_UP | MSigDB lists | GSE12003_4D_VS_8D_CULTURE_BM_PROGENITOR_UP | 153 | 42 | 17377 | 2626 |
CXXC1,SLC2A1,TRIO,NKRF,NOTCH2,SND1,XPO7,DCUN1D4,LYN,CHD1,CLIC4,IARS,CRY2,PCYT2,POLR1B,SLC35C2,NUDC,SOCS5,RYBP,CSTF1,PLK3,PPAN,TMEM39A,BTG2,SLC26A6,ITM2A,SLC25A22,BOLA1,RANGAP1,MFN2,GEMIN5,UTP20,KPNA1,AXIN1,TBL3,IMPDH1,PSAP,NMD3,ABCA1,IPO4,GPATCH4,ZC3HC1 |
| 5.851e-05 | -9.75 | TUBB2A (tubulin beta 2A class IIa) | protein interactions | 7280 | 121 | 37 | 17029 | 2761 |
UBXN1,TWF2,PCBP1,TUBGCP2,GLMP,RPA2,CAPN2,MDM2,PTEN,HUWE1,MCM5,AHSA1,ZNF746,NSFL1C,UPF2,CCT2,PTPN18,TK1,CUL3,TUFM,ADRB2,METTL22,MCM2,GFER,EML4,FAS,HGS,PLAA,QARS,RPLP1,CD81,ARRB2,CDK2,TERF1,POT1,ZNF146,TUBB |
| 5.861e-05 | -9.74 | HIST2H3C (histone cluster 2 H3 family member c) | protein interactions | 126961 | 95 | 31 | 17029 | 2761 |
BRD4,NASP,KAT2A,CXXC1,MECP2,MUM1,CDCA8,SMARCA4,WDHD1,AURKB,BRCA1,SMC2,KMT2C,MCM2,HDGFL2,KDM3A,CHAF1A,DOT1L,PCNA,KDM2A,BIRC5,STAT6,MTA1,STAT1,H2AFX,KMT2B,BRD7,NAP1L4,RBBP4,CD81,ARID4A |
| 5.861e-05 | -9.74 | SSBP1 (single stranded DNA binding protein 1) | protein interactions | 6742 | 95 | 31 | 17029 | 2761 |
COX15,MRPS2,SF3B1,TCF3,LDB1,VDAC2,ILF3,CUL3,LAMTOR3,CUL1,NFATC2,OGDH,VDAC1,ASB13,KCMF1,PARK7,CAND1,MTMR3,SDHB,PCM1,INTS7,HNRNPH3,PTPN7,NABP2,H2AFX,ACAT1,YBX1,FUS,CYC1,MRPL11,CDK2 |
| 5.978e-05 | -9.72 | PRPF31 (pre-mRNA processing factor 31) | protein interactions | 26121 | 148 | 43 | 17029 | 2761 |
SART1,CYLD,XAB2,SF3B1,OLA1,USP39,SNRPD3,RBM4,FBRS,PHC2,UTP25,CTNNBL1,SIAH1,AHSA1,ZNF746,EFTUD2,CTR9,UPF2,TP53BP2,FBL,IFT46,COPS8,CCDC57,SNRNP200,SNRPB,RNPS1,CUL3,KRAS,PRPF3,SF3A2,CHAF1A,DDX23,KPNA1,GOLGA2,RBM25,LSM6,CDCA7L,TFDP1,KPNA2,PRPF4,SNRPG,SMURF1,PRPF4B |
| 5.978e-05 | -9.72 | RAN (RAN, member RAS oncogene family) | protein interactions | 5901 | 148 | 43 | 17029 | 2761 |
CYLD,NEMP2,SUZ12,GADD45G,IKBIP,XPO7,UBE2I,CDC73,MAD2L2,TFAP4,ASAP2,EIF2S2,SNUPN,EIF4A3,PPME1,NUP107,H2AFY,TNPO2,TRA2B,CRY2,NUP153,STAU1,NXT1,SF3B6,CDCA2,RANGAP1,ADRB2,NUTF2,BRCA1,ISG15,KPNA4,KPNA1,SMAD2,BIRC5,PFDN4,NSMF,NUP62,KPNA2,FUS,SMAD1,CDK2,TAF6,SSRP1 |
| 5.995e-05 | -9.72 | ribonucleoprotein complex binding | molecular function | GO:0043021 | 118 | 35 | 17224 | 2647 |
DHX9,YTHDF3,LETMD1,TOP2B,SECISBP2,EFL1,SNRPD3,MDM2,EIF4A3,NVL,PELO,MRPS27,LTN1,RPN2,RNF135,TIMM50,EIF5A,SRP72,DHX29,EIF2A,EIF4H,PHF6,RPSA,SNRPA,GEMIN5,EIF3K,SEC61A1,PQBP1,PRMT7,DDX5,RNASEL,SNRNP70,NMD3,ZNF598,CPEB2 |
| 6.007e-05 | -9.72 | MTF1 (metal regulatory transcription factor 1) | protein interactions | 4520 | 108 | 34 | 17029 | 2761 |
DNAJC2,COPA,NOP2,PHB2,SF3B1,DHX9,RPL15,NKRF,RPL11,RPL23A,SF3B2,HNRNPA2B1,EFTUD2,AP1M1,NOC2L,RPL19,FBL,HNRNPM,PRPF19,SNRNP200,PRKDC,GTPBP4,ILF3,RPL8,RPS9,MATR3,DHX15,SRSF1,SUPT16H,DDX17,XRCC5,RBMX,DDX5,PDCD11 |
| 6.030e-05 | -9.72 | SMC3 (structural maintenance of chromosomes 3) | protein interactions | 9126 | 139 | 41 | 17029 | 2761 |
FEZ2,IVNS1ABP,SUZ12,RAE1,MECP2,MAGED1,CTCF,SMARCA4,MXD4,BECN1,TMEM165,SDHA,MXD1,ANKRD28,RPA2,NEK6,PDS5B,KIFAP3,CEP63,CLTB,MSH6,HNRNPM,TERF2,CDC5L,PLK1,MAPRE2,CUL3,ARHGEF12,BRCA1,SMC2,MCM2,POLR2A,RPA1,NSMCE2,CDCA5,CHMP4B,COPS6,CDK2,TUBB,HDAC2,USP13 |
| 6.038e-05 | -9.71 | spliceosomal snRNP assembly | biological process | GO:0000387 | 38 | 16 | 17256 | 2622 |
GEMIN5,SART1,SNUPN,SNRPB,PRMT7,DDX20,GEMIN6,GEMIN4,SNRPG,PRPF3,SNRPD3,STRAP,CLNS1A,GEMIN7,PRPF19,SRSF10 |
| 6.038e-05 | -9.71 | ncRNA export from nucleus | biological process | GO:0097064 | 38 | 16 | 17256 | 2622 |
NDC1,NUP188,RAE1,NUP54,NUP155,RPSA,NUP205,TSC1,NUP210,NUP107,NUP153,NUP62,NUP58,NUP85,SEH1L,AAAS |
| 6.054e-05 | -9.71 | neutrophil mediated immunity | biological process | GO:0002446 | 493 | 107 | 17256 | 2622 |
RHOG,ADA2,RAB14,KMT2E,ADAM10,DYNLL1,RAC1,HEXB,NIT2,NHLRC3,GYG1,MAPK14,KCMF1,CMTM6,CPNE3,PA2G4,RAP1A,PSMD1,AP1M1,BRI3,TMBIM1,GM2A,KCNAB2,ENPP4,CPNE1,CCT2,TIMP2,NRAS,RAB7A,ARHGAP45,PPIE,CYSTM1,PSMB7,ATP6V0A1,RAB5B,TOLLIP,ALDH3B1,DSN1,AGPAT2,DDOST,SURF4,RAB24,PSMD3,CAB39,CANT1,ATP6V0C,ROCK1,PDXK,LTA4H,MAPK1,CAPN1,TUBB,SVIP,MIF,DNAJC5,GMFG,MANBA,PDAP1,LAMTOR3,B4GALT1,ASAH1,CDK13,MAN2B1,RAB6A,PSEN1,TMEM179B,GNS,CD59,PSMD2,CTSS,ARPC5,HUWE1,OSTF1,CNN2,MVP,LPCAT1,SPTAN1,CYFIP1,FTL,MLEC,RHOA,ADAM17,CREG1,WDR1,HEBP2,C1orf35,PKM,ARMC8,CCT8,NEU1,HSPA1B,CAND1,XRCC5,CAT,RAB18,ATP6V1D,MAGT1,GOLGA7,SNAP29,SNAP23,ACLY,PGRMC1,IMPDH1,CTSA,PSAP,GPI,PGAM1 |
| 6.065e-05 | -9.71 | TAGCTTT,MIR-9 | MSigDB lists | TAGCTTT,MIR-9 | 228 | 57 | 17377 | 2626 |
UBE2D3,POU3F2,RAB14,NSMCE4A,MECP2,GSPT2,KLC1,NKRF,AGFG1,MXD1,FBXO22,SLC25A37,HNRNPA2B1,C18orf32,PPP1R8,JAZF1,PDS5B,TARDBP,TCEA1,GNAI2,SENP1,DVL2,CAMK2G,PHF20L1,ZMYND11,E2F3,ATXN1,CKAP2L,KRAS,MTMR12,FAM133B,FXR1,SOX4,STX16,PHF6,DPYSL3,KRIT1,ANKRD10,GOLGA4,EIF4ENIF1,SERF2,ZHX1,UEVLD,OSBPL8,ARNTL,STAT1,ITGB1,SOCS4,PPP3R1,VCPIP1,SLC16A1,HMGB2,YWHAZ,NR2F2,CPEB2,ATMIN,PRPF4B |
| 6.065e-05 | -9.71 | - | gene3d domains | 1.20.920.10 | 44 | 18 | 8148 | 1295 |
ASH1L,BRD4,KAT2A,BAZ2A,ZMYND11,SMARCA4,PBRM1,TRIM28,ATAD2,BRD2,SP100,BRWD1,BRPF3,KMT2B,BAZ1B,BRD7,BRWD3,BRD9 |
| 6.079e-05 | -9.71 | regulation of binding | biological process | GO:0051098 | 352 | 81 | 17256 | 2622 |
TXN,CYLD,ADD1,EIF3D,SIRT2,PRKACA,STMN1,PARK7,APP,RPL11,CDK5,SP100,EIF4A3,RALB,PIN1,SRI,PLCL2,CARM1,PLK1,BAK1,CPNE1,EDF1,AURKB,TRIM28,BTBD1,KRIT1,DOT1L,EPB41,PPP2CA,SMAD2,HIPK2,MIA2,TICAM1,ACTB,DVL1,ROCK1,ARRB2,NMD3,SMAD4,HDAC2,MAPRE1,HJURP,DNAJB2,CDT1,HABP4,DHX9,FLOT1,CSNK1A1,PSEN1,MAD2L2,DDRGK1,GTF2F1,FKBP1A,TFAP4,RB1,IRF4,MBD2,GTSE1,BCL2,TGFB1,PPP3CA,KAT2A,BTAF1,MFNG,GTPBP4,ADRB2,MEN1,SYMPK,MAPK3,DERL1,PTPRF,GOLGA2,CDCA5,CEBPG,E2F1,PRMT7,ZFP90,HMGB2,RUVBL2,IFI16,SNAPIN |
| 6.088e-05 | -9.71 | GSE21927_UNTREATED_VS_GMCSF_GCSF_TREATED_BONE_MARROW_UP | MSigDB lists | GSE21927_UNTREATED_VS_GMCSF_GCSF_TREATED_BONE_MARROW_UP | 163 | 44 | 17377 | 2626 |
ZBTB10,MAGEH1,GXYLT1,B4GALT5,GSPT2,OLA1,AGPAT1,HMGN3,IL21R,MRPL19,PARK7,TNS3,JAZF1,ATP13A3,RAD23B,AXIN2,ARL6IP1,RPF2,SLC38A10,ALDH18A1,TMEM14C,N4BP2,HDHD2,SP3,RFC3,RNASEH2C,CREG1,ACSL3,CAPZA2,SOX4,KDM1B,ANLN,TMEM201,IWS1,EPB41,TTC13,LRPPRC,C4orf46,BEND3,YY1,H3F3A,ZMIZ1,TSEN15,ANAPC4 |
| 6.088e-05 | -9.71 | LASTOWSKA_NEUROBLASTOMA_COPY_NUMBER_UP | MSigDB lists | LASTOWSKA_NEUROBLASTOMA_COPY_NUMBER_UP | 163 | 44 | 17377 | 2626 |
INTS2,NAT9,PHF23,SUMO2,TMEM97,SMC6,JMJD6,EZH1,SYNRG,NOL11,EIF4A3,UTP18,AXIN2,SLC38A10,RNF135,STAT3,LRRC59,NUP85,FTSJ3,TK1,RPL38,MRPL12,RFFL,CDC6,BRCA1,ICAM2,POLG2,GOSR1,DHX57,SRSF1,AKAP1,RAD51C,SGSH,KIF18B,BIRC5,GPS2,LUC7L3,MRPL27,ACBD4,SLC25A19,PITPNA,KPNA2,ARHGAP23,GEN1 |
| 6.088e-05 | -9.71 | GSE27241_WT_VS_RORGT_KO_TH17_POLARIZED_CD4_TCELL_TREATED_WITH_DIGOXIN_UP | MSigDB lists | GSE27241_WT_VS_RORGT_KO_TH17_POLARIZED_CD4_TCELL_TREATED_WITH_DIGOXIN_UP | 163 | 44 | 17377 | 2626 |
GXYLT1,TSC2,NF1,ZBTB37,KLHL18,ATG2B,MYO9B,DOCK11,NUP205,RPL11,RB1,CEP104,CLIC4,ATP2A2,KDM2A,KIF14,ATP13A3,KNTC1,CDC25B,MAST2,CNOT6L,CELSR2,BAZ2A,KAT7,TAOK1,MAP4K4,KIF15,UBE4B,BRCA1,ARID1A,SMC2,MACF1,ERC1,IWS1,TRIM26,PCM1,ATAD2,POLE,TTLL4,RPS27A,KHSRP,BAZ1B,ESPL1,SMARCD1 |
| 6.088e-05 | -9.71 | GSE1925_CTRL_VS_IFNG_PRIMED_MACROPHAGE_3H_IFNG_STIM_UP | MSigDB lists | GSE1925_CTRL_VS_IFNG_PRIMED_MACROPHAGE_3H_IFNG_STIM_UP | 163 | 44 | 17377 | 2626 |
DDX58,RPS2,TOMM20,ZBTB37,NACA,PRKAA1,PTTG1,TMX3,MYH9,LETMD1,XPO7,RAPGEF6,NUP205,CTSS,HUWE1,ZNHIT6,FIZ1,RAD23B,EXOSC1,SLC35B4,PDS5B,GLTP,UBE3B,FBL,CNOT6L,GCC2,TSTA3,SIGMAR1,RPL36,UBTF,UTP20,MRPL2,RAD18,TTLL4,GRIPAP1,HIPK2,RBMX,STAT1,CRCP,CNOT6,PPP6R3,LTA4H,TRAF5,RPS26 |
| 6.089e-05 | -9.71 | GO_MITOCHONDRIAL_ELECTRON_TRANSPORT_NADH_TO_UBIQUINONE | MSigDB lists | GO_MITOCHONDRIAL_ELECTRON_TRANSPORT_NADH_TO_UBIQUINONE | 42 | 17 | 17377 | 2626 |
NDUFA5,NDUFV2,NDUFS1,NDUFB6,NDUFA4,NDUFA7,NDUFB1,NDUFS7,NDUFS4,NDUFV1,NDUFA2,NDUFB4,NDUFA11,NDUFS8,NDUFB9,NDUFS5,NDUFA3 |
| 6.089e-05 | -9.71 | GNF2_INPP5D | MSigDB lists | GNF2_INPP5D | 42 | 17 | 17377 | 2626 |
CSNK1G2,CYTIP,HLA-E,ACTR3,TAP1,MFNG,WIPF1,ARHGDIB,CBFB,HLA-A,VAV1,HLA-B,WAS,CSK,STAT6,CORO1A,IFI16 |
| 6.093e-05 | -9.71 | NLE1 (notchless homolog 1) | protein interactions | 54475 | 36 | 16 | 17029 | 2761 |
NOP9,NOL12,CCT2,NIFK,EWSR1,MECP2,CUL3,RPL15,CYCS,WDR5,RBM4,NSA2,HNRNPH3,CHMP4B,IFI16,GPATCH4 |
| 6.093e-05 | -9.71 | GINS3 (GINS complex subunit 3) | protein interactions | 64785 | 36 | 16 | 17029 | 2761 |
GINS1,CSNK1G2,CLSPN,H2AFX,CTPS1,TIMELESS,WDHD1,MCM2,PPP5C,RFC2,IGBP1,BZW2,ABHD14A,CAPN1,GINS4,SSRP1 |
| 6.093e-05 | -9.71 | C1orf131 (chromosome 1 open reading frame 131) | protein interactions | 128061 | 36 | 16 | 17029 | 2761 |
KARS,EIF3L,RPS15,EPRS,SNRNP200,C1orf131,EWSR1,IARS,RPL17,QARS,KRAS,SNN,LRRC59,CDC73,APP,RPL23A |
| 6.093e-05 | -9.71 | MOGS (mannosyl-oligosaccharide glucosidase) | protein interactions | 7841 | 36 | 16 | 17029 | 2761 |
STAU1,POLR2G,HNRNPR,ZNF746,UBA5,HNRNPF,RPS24,NUP62,AURKB,TECR,MCM2,USP11,HAUS2,NCDN,MORC3,EVC2 |
| 6.093e-05 | -9.71 | NUTF2 (nuclear transport factor 2) | protein interactions | 10204 | 36 | 16 | 17029 | 2761 |
RHOA,RAB11B,RAB7A,NUP54,NUTF2,FKBP2,RAB11A,HINT1,NAXE,NUP153,NUP62,TAGLN2,PGAM1,LUC7L2,KCNAB2,GPX4 |
| 6.138e-05 | -9.70 | GO_CONDENSED_CHROMOSOME_CENTROMERIC_REGION | MSigDB lists | GO_CONDENSED_CHROMOSOME_CENTROMERIC_REGION | 88 | 28 | 17377 | 2626 |
ZNF207,PLK1,SKA3,HJURP,CENPF,NUF2,RANGAP1,KIF2C,PMF1,AURKB,SEPT7,CCNB1,CSNK1A1,MIS12,SPAG5,PHF6,CBX3,AHCTF1,DSN1,BIRC5,NUP107,SS18L1,KNTC1,CENPM,CENPT,NDE1,NUP85,SEH1L |
| 6.138e-05 | -9.70 | REACTOME_MHC_CLASS_II_ANTIGEN_PRESENTATION | MSigDB lists | REACTOME_MHC_CLASS_II_ANTIGEN_PRESENTATION | 88 | 28 | 17377 | 2626 |
KIF3B,DYNLL1,RAB7A,DCTN2,KIF15,KLC1,KIF23,RACGAP1,KIF2C,ARF1,AP1B1,KIF11,SEC31A,KIF5B,KIF2A,CTSS,KIF18A,SEC24C,DNM2,AP1M1,AP2B1,AP1S1,CTSA,KIF22,KIFAP3,AP2S1,DYNC1LI2,DCTN1 |
| 6.153e-05 | -9.70 | HMG17 | smart domains | SM00527 | 5 | 5 | 9493 | 1367 |
HMGN3,HMGN1,HMGN5,HMGN4,HMGN2 |
| 6.168e-05 | -9.69 | vesicle | cellular component | GO:0031982 | 3810 | 641 | 18223 | 2701 |
CCDC93,RAB14,TMED7,HEXB,TGOLN2,SYNRG,CMTM6,RPL23A,CALM2,NAPG,PSMD1,RABGAP1L,AP1M1,DNM2,MOB1A,MGAT5,KCNAB2,PCBP2,RHOBTB3,NRAS,SMC2,NUTF2,PPFIA3,RAB22A,PLEKHF2,ARF4,AHNAK,RPS27A,AXIN1,PRDX5,VIPAS39,ATP6V0C,ANXA11,PFKP,GGA1,RHOC,CCZ1,CUTA,RAB23,TMED3,ITGB5,APH1B,MYL6B,COPB2,TMEM179B,GNS,CD59,MEGF8,GEMIN4,MVP,PABPC1,PPA1,CYFIP1,PRRC2A,MAN1B1,ITM2A,USP10,RHOB,PTPRF,MAGED2,SCARB2,OSBPL11,TXNDC16,CSK,MDH1,CFAP20,HEXA,SNX14,ALS2,RHOG,EXOC3,ANKRD27,ABCA3,GGNBP2,ACTR3,MON1B,VTI1A,MYH9,NIPA2,NIT2,PRKACA,SAFB2,STMN1,STAM,CPNE3,APP,RAB21,AHCTF1,ATP2A2,DUT,TBC1D14,CLCN6,GPD1L,TMEM9,ATP6V1G1,ENPP4,SNX8,CPNE1,GOPC,ATP6V0A1,DNAJA1,GSTCD,RAB1A,CHCHD3,PPP2CA,ALDH3B1,VPS26B,CORO1C,WDR7,TICAM1,PDXK,TUBB,GALK1,RPS2,ANXA6,TRAK1,FLOT1,ABHD14B,ATP5F1B,PMVK,IFT27,TUT4,CAPN2,PSMD2,PDCD10,CLIC4,ITGB8,HUWE1,ARF5,NAA50,ANXA5,ST8SIA2,TPCN1,S100A6,HNRNPM,LYPLA2,SPTAN1,LDHB,PDPK1,STAU1,TNFAIP3,LDHA,HEBP2,PICALM,MAGT1,WNT5B,CAPN7,FAM3C,DBI,PML,LY75,PSAP,CD81,YWHAH,SNAPIN,AGRN,GNPDA1,FAM129A,SNX15,SND1,SEC16A,RUFY1,KCMF1,PRNP,RAB8A,PCNA,IL6ST,SLC44A1,ZFYVE27,CDC37,MBLAC2,CYSTM1,EZR,UBE2V1,RAB5B,RHEB,DPYSL3,OPTN,NECAP2,TBC1D17,AGPAT2,GRIPAP1,NAGLU,ADAM9,ARRDC1,ACTB,DVL1,CLN3,MYL12B,C2CD5,NUMB,TMUB1,NKD2,LAMTOR3,KLC1,ASAH1,RACGAP1,CDK13,RAB6A,DNAJB1,NCKAP1,RAPGEF6,SUB1,VASP,RINL,AHCY,TMEM8A,HDHD2,ABCC1,ABHD2,NQO2,ARPC1A,ARMC8,APPL1,RMC1,GOLGA4,TMEM168,SNAP23,LAMTOR4,RUVBL2,ATP5F1A,ECPAS,UNC13C,NIPA1,TRAF7,UGP2,RPLP2,DYNLL1,COPE,SLC2A1,ZFYVE21,RRAGC,ATP6V1B2,PCBP1,LYN,BCAP31,RPL11,NRF1,ATP6V0B,PSMA6,MDM2,WDR44,PDCD2,CORO1A,MINPP1,AHCYL1,LMAN1,GM2A,DVL2,SNX25,CLCN3,TIMP2,PSMA8,PPT1,BTG2,RAB7A,PPIE,SLC26A6,CHMP2B,VDAC1,EIF3H,RPSA,GLOD4,ATP1A1,CLK3,SCAP,PSMD3,AP1S1,CHMP4B,H3F3A,LTA4H,CHID1,AP2S1,SLC30A9,GOLIM4,PDAP1,AGO2,TMX3,ARF1,SLC12A9,GGA2,AP3S1,SCYL2,FZD6,TFRC,DNAJB9,HERC3,GSTK1,CTSS,SLC1A4,CAMK2G,MLEC,ACP2,RHOA,CSRP1,SNX2,TUFM,ARHGEF12,NEU1,DDX23,RAB18,PDCD6,ATP6V1D,SEC23IP,GOLGA7,SNAP29,GLG1,PGRMC1,IMPDH1,PKD2,PGAM1,CHMP7,RPS6KC1,ARHGAP23,SAT2,TXN,PDCD6IP,H2AFZ,LUZP1,ADAM10,ZDHHC8,AP3M2,TMEM109,TAP1,GYG1,NHLRC3,PLXNA1,NANS,PARK7,KIFC1,PA2G4,DBNDD1,RAB4A,AP2B1,MARCH2,SLC26A2,USO1,ATG9A,AKT2,ARHGAP45,GNG7,SLC17A5,GALNT7,MCFD2,RAB2B,WAS,TMED10,RPS14,PTER,ITGB1,ARRB2,SVIP,PPIB,HSPH1,DNAJC5,SCOC,GMFG,HLA-E,ACAP1,B4GALT1,MAN2B1,PSEN1,TMEM165,VPS25,COPG2,WDR48,RPN1,SLC31A1,ARPC5,SNX18,ZNRF2,ATIC,ATP6V0A2,OSTF1,PIKFYVE,GNAI2,LPCAT1,SYTL3,TMED2,FTL,PIGT,SIGMAR1,CPQ,WDR1,PIP4K2C,C1orf35,EXOSC9,ADRB2,CAPZA2,PLEC,PTTG1IP,PKM,CYFIP2,GOSR1,MAP2K2,CCT8,PSMB3,FAS,XRCC5,PI4K2A,SEC31A,CAT,DERL1,ADSS,GOLGA2,RBMX,ACLY,ARAP1,APPL2,GPI,CDK2,CYTIP,RAB11B,TRIP10,RAC1,GPR89A,OLA1,BCL2L1,AP1B1,GNB2,CD320,CRKL,APLP2,RALB,MTMR4,SIAH1,CDKN1B,BRI3,TAP2,TALDO1,CFL1,TMBIM1,GPX4,CCT2,TAOK1,CUL3,VDAC2,PSMB9,H2AFV,AP4E1,CHMP4A,HSPA4,JAK1,DSN1,DDOST,HINT1,RAB24,H2AFX,B4GALT3,DYNC1LI2,ANKRD13D,SCAMP3,MANBA,TKT,SPR,RAB11A,HEATR5B,HLA-A,EBP,WWP2,PIP5K1C,MAT2B,AHSA1,FUT8,CNN2,TAGLN2,STRIP1,DENND1B,DENND4C,PARP4,PACS1,KCNQ1,SPPL2B,ECH1,SH3GLB1,PRDX1,YIF1A,TMEM127,NUCB1,PLD3,SGSH,HGS,PRDX3,CCZ1B,NAXE,ASNA1,DDX5,WDR91,VPS29,DDB1,ADA2,UBL3,MIB2,ST13,COPA,MOGS,PTP4A3,TAF6L,AGFG1,UBQLN2,MAP1LC3B,MAPK14,BECN1,PCYOX1L,DST,RAP1A,CDC42,GOT2,AP3S2,ZNHIT6,RAB35,DPYSL2,SRI,AKR1B1,RP2,CARMIL1,COPS8,NCK1,LAP3,ARHGDIB,CXXC4,UEVLD,CRCP,CAB39,STK11,CLU,VPS4A,ROCK1,RPS26,ATP6V0E1,CAPN1,STARD3NL,UBE2D3,TBC1D12,AGTRAP,TM9SF4,UFC1,CDIP1,CIB1,THRAP3,EPHX2,CAPZA1,YBX1,SLC12A2,ATP6V0D1,ALDH9A1,KDELR1,VOPP1,TSTA3,CREG1,GBA,PSMA1,SEPT7,CAND1,GNAS,NAP1L1,SIAH2,SLC16A1,YWHAZ,CTSA,DNPH1,PITPNA,EHD4,N4BP2L2,WASF2,SNX27,CHMP2A,CORO7,GNPNAT1,MDH2,TWF2,EXT2,HNRNPA2B1,IARS,SAR1A,CS,CYB5R1,APOOL,CLTB,F2R,PDIA6,ABI1,EBAG9,CHP1,UBQLN4,PSMB7,WIPF1,GLO1,BICD2,PEF1,TOLLIP,RPS9,VPS26C,SURF4,TAB2,CANT1,ANP32E,FKBP5,SCARB1,SMURF1,MAPK1,ABCA1,TMEM33,MIF,KIF3B,TOR3A,SCYL1,SRGN,DCTN2,VPS45,CHIC2,MFSD10,MAN1A1,FERMT3,SPPL2A,KIF5B,FGFR3,GART,SEC24C,ZDHHC13,H2AFY,ARHGEF2,YIF1B,FBL,MYO5A,SLC25A1,TGFB1,FAM49B,RFFL,WDR81,NDRG3,TARS,MAPK3,HSPA1B,CTSL,HLA-B,ATAD2,PLAA,ACAT1,ATP6V1C1,PLOD3 |
| 6.186e-05 | -9.69 | GSE2770_IL4_ACT_VS_ACT_CD4_TCELL_6H_UP | MSigDB lists | GSE2770_IL4_ACT_VS_ACT_CD4_TCELL_6H_UP | 168 | 45 | 17377 | 2626 |
MIB2,MIF4GD,RWDD1,ANXA6,REPS2,DHPS,TCF3,TKT,ABHD14B,NDUFS7,ADD3,MZT2A,DUT,MCM5,SIVA1,RCSD1,CS,AP1M1,ANP32A,SLC38A10,TAGLN2,MRPL40,ARL5A,CAMK2G,SPSB3,PGAP2,MAPRE2,WDR18,EZR,SUMF2,EIF2AK1,IL12RB1,MTX1,SRSF5,ESYT1,PSMB9,STX16,ALDH3B1,WAS,QARS,EXOC4,NLRC5,MBOAT1,COPS6,NMD3 |
| 6.186e-05 | -9.69 | PYEON_CANCER_HEAD_AND_NECK_VS_CERVICAL_UP | MSigDB lists | PYEON_CANCER_HEAD_AND_NECK_VS_CERVICAL_UP | 168 | 45 | 17377 | 2626 |
MRPL39,CENPF,NUF2,B4GALT4,PRPF39,RMI1,DTL,FANCL,GART,AHCTF1,NUP210,NDUFB4,INTS7,CENPJ,SS18L1,ANKRD13C,KNTC1,RBM15,MCPH1,FGFR1OP2,SMC4,FDFT1,GINS1,ANKLE2,ERMP1,NASP,RAD51AP1,KIF15,WDHD1,OSBPL11,ATAD2,ETS2,TXNDC16,BRWD1,RBL1,CCDC14,GOLGA8A,ZNF367,U2SURP,PRPS2,WDR76,RBBP4,GEN1,EYA2,CDKN2A |
| 6.186e-05 | -9.69 | GSE37416_CTRL_VS_3H_F_TULARENSIS_LVS_NEUTROPHIL_UP | MSigDB lists | GSE37416_CTRL_VS_3H_F_TULARENSIS_LVS_NEUTROPHIL_UP | 168 | 45 | 17377 | 2626 |
ASH1L,ANKRD13D,CDC40,GXYLT1,UBN1,CCM2,C5orf30,ASAH1,CSNK2A1,SLC25A44,CRLF3,FAM8A1,RRP36,TMEM69,ZNF302,RABGAP1L,GRSF1,POP7,CORO1A,TALDO1,RBM12B,S100A6,RBM15B,CDKN2AIP,NOA1,JTB,UTP15,CIRBP,FRAT2,FBXO9,WDR82,DCLRE1C,HERPUD2,PI4K2A,GNAS,ZNF180,HHEX,CDKN2AIPNL,PDCD6,SCAP,HIPK2,CCDC69,WIPI2,CHPF2,PSMC1 |
| 6.195e-05 | -9.69 | GO_REGULATION_OF_RESPONSE_TO_STRESS | MSigDB lists | GO_REGULATION_OF_RESPONSE_TO_STRESS | 1414 | 265 | 17377 | 2626 |
NUP188,TXN,TMEM203,ZDHHC8,TAP1,XIAP,CUL1,ELMOD2,PARK7,CDK5,USF1,PSMD1,NEK6,DNAAF2,AP1M1,AP2B1,NUP153,PCBP2,SEH1L,MLST8,BAK1,PGAP2,NRAS,PBK,MCL1,MAP3K4,RPS27A,PSMD8,AXIN1,OGT,ATP6V0C,ARRB2,AAAS,PDCD4,SVIP,DDX58,HSPH1,SCOC,MRPS2,PHF23,HLA-E,VAV2,GADD45G,EIF2AK4,PSMD9,CD59,ATP6V0A2,RNF135,PIKFYVE,NUP85,TERF2,SOCS5,MAPKAPK3,ZMYND11,PIP4K2C,BCLAF1,ADRB2,PTTG1IP,MAP2K2,PSMB3,PTPRF,DUSP3,CEBPG,MDH1,MAP3K5,ZC3HAV1,CDKN2A,ATXN3,RAF1,RAC1,BCL2L1,AP1B1,PRKACA,EPM2A,TERF2IP,RALB,MTA1,TBC1D14,NUP107,MAVS,C8orf59,RNF169,ATP6V1G1,ENPP4,BRD4,MAP4K4,TAOK1,CRNKL1,ATP6V0A1,DNAJA1,PSMB9,TRIM28,CHMP4A,JAK1,VPS26B,HIPK2,STAT1,H2AFX,TICAM1,TRIM32,USP13,POLQ,SRSF6,BABAM1,FLOT1,SDF2L1,AKT1S1,ETS1,HLA-A,RFWD3,RPA2,PSMD2,PDCD10,PTEN,FUT8,PTPN11,AXIN2,FEM1B,ANXA5,CNPY3,PDPK1,PPP3CA,TNFAIP3,KAT2A,MRPS10,HEBP2,PACS1,KCNQ1,ZP3,SH3GLB1,FADD,PRDX1,RPA1,GPS2,PML,SLC25A19,HMGB2,DDX5,PSAP,IGBP1,THOC1,PPP1R15B,ALKBH5,SIRT2,UBQLN2,BECN1,MAPK14,MAP1LC3B,BIRC2,FANCL,NUP210,PCNA,CDC42,IL6ST,OGG1,CDC37,NCK1,SNRPB,RAD51AP1,EZR,UBE2V1,IL12RB1,BRCA1,CHEK2,CLU,CLN3,ATP6V0E1,PSMC1,CAPN1,UBE2D3,TBC1D12,NSMCE4A,PHB2,UBXN1,CHCHD2,DNAJB1,NUP205,MDFIC,LRSAM1,ATP6V0D1,ZNF189,TRAFD1,GBA,PSMA1,EIF2AK1,KRAS,SYVN1,ICAM2,PSMC4,TSC1,MBIP,NLRC5,EXOC4,NUP62,ASH1L,CYLD,FEZ2,FOXM1,IRF3,ATP6V1B2,LYN,DUSP22,BCAP31,VAV1,ATP6V0B,PSMA6,MDM2,PARL,F2R,HTRA2,DVL2,UBQLN4,BIRC3,PSMA8,RAB7A,PSMB7,NUP155,CADM1,EDEM2,VDAC1,USP36,TAB2,PSMD3,GADD45B,ARNTL,AP1S1,CHMP4B,SMURF1,MAPK1,CHID1,AP2S1,TMEM33,MIF,BCL2L12,DNAJC2,TRIP12,EYA1,RAE1,NUP54,ARF1,PIP4K2A,PTPN2,IRF4,CTSS,TANK,ARHGEF2,PTGES3,CAMK2G,RNF5,TGFB1,TMEM39A,PRKDC,HELB,MEN1,HSPA1B,MAPK3,MTMR3,HLA-B,ATP6V1D,ELMO1,COX8A,ATP6V1C1,HRAS,HIPK3,IFI16 |
| 6.204e-05 | -9.69 | REACTOME_ER_PHAGOSOME_PATHWAY | MSigDB lists | REACTOME_ER_PHAGOSOME_PATHWAY | 58 | 21 | 17377 | 2626 |
SEC61B,PSMA8,SEC61G,TAP1,PSMB7,PSMA1,PSMB9,PSMD9,PSMB3,HLA-A,PSMC4,HLA-B,PSMD2,PSMA6,PSMD1,SEC61A1,RPS27A,PSMD8,PSMD3,TAP2,PSMC1 |
| 6.251e-05 | -9.68 | Mitochondrial translation | REACTOME pathways | R-HSA-5368287 | 94 | 31 | 10287 | 1696 |
MRPL9,MRPL42,MRPS2,MRPS15,MRPL39,MRPS26,MRPL12,MRPL43,TUFM,MRPS10,MRPL16,MRPS14,GFM2,MRPL19,MRPL50,MRPL2,DAP3,MRPL55,CHCHD1,MRPL27,MRPL34,MRPS27,MRPL54,MRPL48,MRPL40,MRPL11,MRPL21,MRPL13,MRPL3,MRPL32,MRPL57 |
| 6.263e-05 | -9.68 | GSE2770_TGFB_AND_IL4_VS_IL4_TREATED_ACT_CD4_TCELL_48H_DN | MSigDB lists | GSE2770_TGFB_AND_IL4_VS_IL4_TREATED_ACT_CD4_TCELL_48H_DN | 173 | 46 | 17377 | 2626 |
MIB2,MIF4GD,CDC40,REPS2,ANXA6,MRI1,TKT,CERK,PRKACA,BZW2,JMY,CDK5,MZT2A,ADD3,ARF5,TBC1D14,AKAP8,XPA,RAB4A,KIF22,GPD1L,TMEM14C,NXT1,MAPRE2,PPT1,MAN1B1,WDR18,MFNG,SUMF2,NFATC2IP,ESYT1,ASB13,STX16,NDRG3,SNRPA,EIF3H,ASF1B,TRAM2,ALDH3B1,L3MBTL3,TATDN2,QARS,TMEM219,MBOAT1,CHPT1,SAT2 |
| 6.263e-05 | -9.68 | GSE36891_UNSTIM_VS_PAM_TLR2_STIM_PERITONEAL_MACROPHAGE_UP | MSigDB lists | GSE36891_UNSTIM_VS_PAM_TLR2_STIM_PERITONEAL_MACROPHAGE_UP | 173 | 46 | 17377 | 2626 |
GNPDA1,MRPS2,RBM8A,NUP54,LAMTOR3,CDC42SE2,DNAJB1,UBQLN2,PMVK,RAPGEF6,QSOX2,RNF103,PAIP2,NAPG,C1GALT1,TNFAIP8,BTF3L4,RBM3,TXNL1,PDPK1,PHF10,EMB,TEX10,POLR2D,LACTB,UTP15,WDHD1,ADRB2,MAK16,TWISTNB,FAS,ADSS,PON2,TAB2,SNAP29,ATP6V0C,PTPDC1,RBBP4,B4GALT3,TFDP2,USF2,PPP2R2D,TERF1,ATMIN,RAB3IL1,RHEBL1 |
| 6.288e-05 | -9.67 | ARRB1 (arrestin beta 1) | protein interactions | 408 | 257 | 66 | 17029 | 2761 |
MYH9,CSNK2A1,KIF2C,MAPK14,STAM,CHD1,KTN1,SF3B2,MDM2,NEK6,CDC42,CD3EAP,PIK3R2,AP2B1,DVL2,CFL1,CUL3,PFKFB3,RAB1A,JAK1,RPS27A,LIMK1,STK38,AXIN1,H2AFX,ARRDC1,PRPF4,DVL1,ROCK1,ARRB2,MAPK1,DCAF5,MYL12B,POT1,TUBB,RPS2,RPL15,ATP5F1B,THRAP3,HDGFL2,SCYL2,PDXP,GRK2,ARPC5,YBX1,HNRNPM,SPTAN1,CYTH1,RPL6,BCLAF1,RTF1,ADRB2,PKM,HSPA1B,XRCC5,MAPK3,HGS,CSK,NSF,ZRANB2,YWHAZ,TCOF1,ATP5F1A,MAP3K5,YY1,YWHAH |
| 6.301e-05 | -9.67 | GO_APOPTOTIC_SIGNALING_PATHWAY | MSigDB lists | GO_APOPTOTIC_SIGNALING_PATHWAY | 280 | 67 | 17377 | 2626 |
SART1,DDX47,NF1,RAF1,TMEM109,CUL1,BCL2L1,MOAP1,PDK2,SIVA1,FNIP2,TP53BP2,SENP1,HTRA2,TIMM50,BAK1,PGAP2,CUL3,MCL1,TOPORS,BRCA1,DIDO1,DNAJC10,DAP3,HINT1,FASTK,HIPK2,STK11,TICAM1,CLU,CHEK2,E2F2,EYA2,ZMAT3,ANXA6,DAP,SRGN,CIB1,CYCS,PAWR,FOXO3,APOPT1,FGFR3,PDCD10,XPA,MSH2,DAPK1,BCL2,MSH6,TGFB1,PDPK1,PRKDC,UBE4B,RHOT1,RHOT2,APPL1,DAPK3,FADD,FAS,PDCD6,E2F1,PML,AEN,DDX5,MAP3K5,HRAS,IFI16 |
| 6.301e-05 | -9.67 | REACTOME_ELONGATION_ARREST_AND_RECOVERY | MSigDB lists | REACTOME_ELONGATION_ARREST_AND_RECOVERY | 24 | 12 | 17377 | 2626 |
CTDP1,POLR2I,POLR2G,POLR2L,POLR2J,POLR2K,POLR2D,TCEA1,POLR2A,SSRP1,SUPT16H,GTF2F1 |
| 6.306e-05 | -9.67 | V$EGR1_01 | MSigDB lists | V$EGR1_01 | 254 | 62 | 17377 | 2626 |
CMAS,PTMS,GPR132,DYNLL1,ANKH,CTCF,HCFC1R1,AP3S1,PRKACA,GNB2,APP,XPR1,WDR48,FAM192A,CDKN2C,APLP2,ITGB8,KDM2A,KLF16,WDR44,SH3BP1,TTC9C,TRA2B,CNN2,CNOT6L,C12orf75,DVL2,CGGBP1,LYPLA2,SOCS5,EIF5A,CLPTM1,HMGN1,RHOA,KAT2A,ERF,KAT7,PRPF3,SYVN1,MATR3,RHOB,HMGN2,IWS1,CAND1,ADSS,MAP3K4,MAN2A2,UBTF,HHEX,BRD2,TFE3,CORO1C,PTPN7,ATXN2L,ATE1,FAM122A,IMPDH1,PITPNA,DDX5,PLOD3,BRWD3,FAF1 |
| 6.321e-05 | -9.67 | GSE25088_CTRL_VS_IL4_AND_ROSIGLITAZONE_STIM_STAT6_KO_MACROPHAGE_UP | MSigDB lists | GSE25088_CTRL_VS_IL4_AND_ROSIGLITAZONE_STIM_STAT6_KO_MACROPHAGE_UP | 178 | 47 | 17377 | 2626 |
SLC30A9,PRPF38B,PIGN,TRERF1,TRAF7,TSC2,RPLP2,SHPRH,BABAM1,KIAA0232,GTF3A,RAB6A,COMMD5,SLC25A37,SRXN1,HOMER1,HUWE1,MTA1,NAA50,RPF2,TTC3,ST8SIA2,NDUFA3,METTL1,PPP3CA,MLEC,POLR2G,APH1A,PRKDC,RPL6,RPL8,KCTD20,ATXN1,ESYT1,CDC23,NMT2,DDX17,TSC1,GALNT2,ATAD2,SEC61A1,RBMX,TPP2,QARS,LRPPRC,IARS2,RTN3 |
| 6.321e-05 | -9.67 | GSE37533_PPARG1_FOXP3_VS_FOXP3_TRANSDUCED_CD4_TCELL_UP | MSigDB lists | GSE37533_PPARG1_FOXP3_VS_FOXP3_TRANSDUCED_CD4_TCELL_UP | 178 | 47 | 17377 | 2626 |
MIF,SRM,TCF12,GOLIM4,UBN1,TMEM41B,ARF1,QSOX2,VPS25,COPB2,JMY,EBP,RALB,DAD1,RRBP1,NSFL1C,CS,GEMIN6,MRPL54,YIF1B,ACAD8,NCOA2,EBAG9,TXNL1,IFRD1,SEPT9,GALC,KAT7,CPOX,GALK2,SMC2,CYFIP2,SNRPA,RHOB,FAS,DERL1,EPRS,PON2,EIF2D,NFIL3,WDR7,COX5A,XRCC3,TAF12,LRP8,ZMAT3,SVIP |
| 6.321e-05 | -9.67 | FERNANDEZ_BOUND_BY_MYC | MSigDB lists | FERNANDEZ_BOUND_BY_MYC | 178 | 47 | 17377 | 2626 |
TCF12,TXN,FOXM1,UROD,SLC4A2,IRF3,ARF1,STMN1,APP,TFRC,LMNA,HNRNPA2B1,MDM2,PTEN,RABGAP1L,CLCN6,RPL19,BCL2,RBM3,CLDND1,RNASEH2A,IMPA2,TGFB1,NRAS,PRKDC,VHL,AMD1,MYBL2,SLBP,MCL1,ELK1,MEN1,RPL27A,CLNS1A,ARF4,HMGN2,AKAP1,MAN2A2,SLC19A1,ETS2,DCK,STAT6,ACOX1,ITGB1,E2F1,ACADM,ZNF146 |
| 6.326e-05 | -9.67 | GMPS (guanine monophosphate synthase) | protein interactions | 8833 | 47 | 19 | 17029 | 2761 |
USP7,TSTA3,AGO2,BABAM1,CUL3,GLO1,BRCA1,RAB1A,MCM2,AGPAT2,PPME1,DDA1,PPM1G,UHRF2,CTPS1,IMPDH1,DDX5,AHCY,CDC5L |
| 6.326e-05 | -9.67 | COMMD4 (COMM domain containing 4) | protein interactions | 54939 | 47 | 19 | 17029 | 2761 |
CCDC93,COMMD10,ARHGAP17,TP53RK,POC1A,COMMD5,COMMD6,COMMD8,PCM1,ATP6V1D,VPS26C,PFDN4,CENPJ,UCHL5,RAD23B,TFDP1,MCMBP,VPS29,PFKP |
| 6.326e-05 | -9.67 | NDUFS5 (NADH:ubiquinone oxidoreductase subunit S5) | protein interactions | 4725 | 47 | 19 | 17029 | 2761 |
NDUFA5,NDUFV2,NDUFS1,NDUFB6,TIMMDC1,LAP3,NDUFA4,NDUFA7,FOXRED1,NDUFS7,NDUFS4,NDUFV1,NDUFA2,HUWE1,NDUFB4,NDUFA11,COX7A2L,NDUFB9,NDUFS8 |
| 6.338e-05 | -9.67 | HNRNPA3 (heterogeneous nuclear ribonucleoprotein A3) | protein interactions | 220988 | 117 | 36 | 17029 | 2761 |
CHMP2A,EWSR1,HNRNPAB,RPLP2,PHB2,MRPS26,CUL1,ATP5F1B,UBQLN2,LMNA,HNRNPA2B1,RPA2,MCM5,TARDBP,SRPK2,STAU1,RAB7A,VHL,HNRNPF,CUL3,SREK1,BRCA1,MCM2,RAB1A,MATR3,SF3A2,PHF6,DDX17,CAND1,RPA1,SYNCRIP,HNRNPH3,FUS,HNRNPDL,SMURF1,CD81 |
| 6.360e-05 | -9.66 | GSE37416_12H_VS_24H_F_TULARENSIS_LVS_NEUTROPHIL_UP | MSigDB lists | GSE37416_12H_VS_24H_F_TULARENSIS_LVS_NEUTROPHIL_UP | 183 | 48 | 17377 | 2626 |
DDX58,USP7,IER2,PRKAA1,YTHDC2,TRAK1,SLC39A13,SDC2,MYH9,HAUS4,ABHD16A,SRXN1,RAB8A,CTSS,ETV6,ORAI1,MAP3K14,CNOT6L,PLCL2,CLTB,TNRC18,S100A6,TACC3,ABCC5,CDC37,AMPD2,PPP3CA,NXT1,TACC1,GMFB,KCTD20,MCL1,DNAJA1,METTL22,FADD,MFN2,VEZF1,TMEM127,TRIM26,TATDN2,PML,CAB39,KPNA2,H3F3A,ZC3HAV1,NUDT3,ADNP2,ZSWIM6 |
| 6.360e-05 | -9.66 | GSE15324_ELF4_KO_VS_WT_ACTIVATED_CD8_TCELL_UP | MSigDB lists | GSE15324_ELF4_KO_VS_WT_ACTIVATED_CD8_TCELL_UP | 183 | 48 | 17377 | 2626 |
MIB2,NAT9,MRPS15,GORASP1,ARFIP2,EIF2AK4,AP3S1,DUSP22,RLF,FAM8A1,CMTM6,RNF103,XPR1,KRR1,FBXL6,MEX3C,PIK3R2,TTC9C,APOOL,PIKFYVE,TMBIM1,ALDH9A1,NIPSNAP1,FYTTD1,RPRD1A,DCAF6,FAM49B,ELL2,PGS1,PPIE,ELP4,GLO1,EIF2A,MCFD2,PRMT2,CHCHD6,GLOD4,CBX3,DDX17,KIF2A,HLA-B,HIPK2,GLG1,ACAT1,ADAM9,FAM126A,CLU,RBPJ |
| 6.360e-05 | -9.66 | GSE29618_PRE_VS_DAY7_POST_LAIV_FLU_VACCINE_PDC_DN | MSigDB lists | GSE29618_PRE_VS_DAY7_POST_LAIV_FLU_VACCINE_PDC_DN | 183 | 48 | 17377 | 2626 |
HSPH1,ADAM10,C1orf112,SRSF6,RBM8A,FLOT1,PPP3CB,PMVK,PDXDC1,MYEF2,DECR1,RRN3,EIF2S2,PTEN,LRRC8D,TANK,BUD31,CAPZA1,AP2B1,LTN1,ZNF226,MAP3K14,ORC3,EIF5,VOPP1,IFRD1,LARS,SNRNP200,HARS,PSPC1,BTAF1,MAP4K4,AZI2,KLF6,API5,MAT2A,GNAS,KPNA1,CDC16,TIMM17A,SNAP23,CEP55,RBMS1,ACAT1,TAF12,NMD3,ACSF2,MRPL3 |
| 6.360e-05 | -9.66 | GSE27786_NKTCELL_VS_NEUTROPHIL_UP | MSigDB lists | GSE27786_NKTCELL_VS_NEUTROPHIL_UP | 183 | 48 | 17377 | 2626 |
SART1,NSMCE4A,ST13,KIAA0100,TAP1,CUL1,COX4I1,NENF,PRPF39,ASXL2,IL21R,MYEF2,RGS1,ATPAF1,SAR1A,THADA,PPIL2,MECR,YBX1,RLIM,NOL12,DDX28,DDX24,TNFAIP3,SCFD2,ADSL,NUP155,PRPSAP1,ODC1,EIF4H,PHF6,VEZF1,MRPL2,ZNF777,TBC1D17,CCDC86,LUC7L3,ARNTL,PPA2,PML,MBOAT1,ZFP90,SPRYD4,BEND3,RBBP4,ZNF598,DCAF5,ZC3HAV1 |
| 6.360e-05 | -9.66 | GSE14908_RESTING_VS_HDM_STIM_CD4_TCELL_ATOPIC_PATIENT_DN | MSigDB lists | GSE14908_RESTING_VS_HDM_STIM_CD4_TCELL_ATOPIC_PATIENT_DN | 183 | 48 | 17377 | 2626 |
RMND5A,PRKAB1,DNAJC5,C16orf87,ANKH,TRIO,CBLL1,PRPF39,PSEN1,CMTM6,DDRGK1,CDKN2C,CAPN2,PDCD10,NUP210,ARF5,MBD2,SLC44A1,ARL6IP1,CDKN1B,BCL2,EIF5,NSUN4,CGGBP1,DCTN1,KDM3B,SP3,TSHZ1,FTL,DPM1,WDR1,PRKDC,PGS1,DENND4C,WBP2,MEF2D,SOX4,MARK2,ISG15,MKNK1,BRD2,GADD45B,RPLP1,DUSP11,CSNK1D,SMNDC1,SNAPIN,TMEM131 |
| 6.377e-05 | -9.66 | TUBA1C (tubulin alpha 1c) | protein interactions | 84790 | 176 | 49 | 17029 | 2761 |
CYLD,FLOT1,CUL1,CDK13,ATP5F1B,ATP6V1B2,GLMP,RPA2,RPN1,MDM2,SHC1,ATP2A2,PTEN,HUWE1,KIF14,PIK3R2,RNF5,TIMM50,CDC5L,CDC37,CCT2,SEC61B,CUL3,RPL8,MAP7D1,AURKB,BRCA1,DNAJA1,ATP5MF,MCM2,FXR1,SLC25A5,CCT8,PHF6,RPA1,CAND1,MAGED2,MRPL2,ATP1A1,AHNAK,TRIM32,ATP5F1A,COPS6,CDK2,ARRB2,CD81,CDKN2A,TUBB,ESYT2 |
| 6.382e-05 | -9.66 | GSE16385_ROSIGLITAZONE_IL4_VS_ROSIGLITAZONE_ALONE_STIM_MACROPHAGE_DN | MSigDB lists | GSE16385_ROSIGLITAZONE_IL4_VS_ROSIGLITAZONE_ALONE_STIM_MACROPHAGE_DN | 188 | 49 | 17377 | 2626 |
NUP54,BLM,IFT27,SDHA,QSOX2,ATPAF1,C14orf119,FKBP1A,SEC11A,FARSA,SLC1A4,COQ4,THADA,CWC27,LRRC8D,NAA35,FAM171A1,RPAP3,TXNL1,GALC,PBK,RAD51AP1,PCGF6,SLC26A6,CKAP2L,CDC6,NUP155,ABHD11,PITPNB,CDC23,AKAP1,EPB41,MRPL2,DNAJC10,MTHFD2,DUS3L,STT3A,DGCR8,CTBS,FAM122A,MEGF9,GAS2,BEND3,WDR76,PPP5C,SASS6,PITRM1,SLC25A39,NIPA1 |
| 6.382e-05 | -9.66 | GSE411_UNSTIM_VS_400MIN_IL6_STIM_MACROPHAGE_DN | MSigDB lists | GSE411_UNSTIM_VS_400MIN_IL6_STIM_MACROPHAGE_DN | 188 | 49 | 17377 | 2626 |
USP7,ZNF76,ZNF496,C19orf53,FAM207A,TMEM41B,CUTA,OLA1,SLC29A1,NANS,PMF1,POLR3K,TERF2IP,PTPN2,SMC3,BTF3L4,NAA50,CS,PDS5B,TRA2B,RNASEH2A,MTX2,UBE2M,IFT46,POC5,MRPL32,NUDC,FDFT1,TDP1,PRRC2A,GNG7,TYW1,CCDC34,HEBP2,ELP4,FAM133B,PDE3B,EPB41,MBIP,NSMCE2,MRPL27,EXOC4,SLC16A1,LY75,SLAIN1,BEND3,SASS6,FAM83G,TUBB |
| 6.382e-05 | -9.66 | GSE17721_CPG_VS_GARDIQUIMOD_4H_BMDC_DN | MSigDB lists | GSE17721_CPG_VS_GARDIQUIMOD_4H_BMDC_DN | 188 | 49 | 17377 | 2626 |
RHOG,DNAJC5,TSC2,GNPDA1,PHF23,TSC22D3,SLC2A1,EPN1,IRF3,ATP6V1B2,SEC16A,FBRS,FERMT3,SRXN1,PRNP,PDK2,ADD3,DNAJC8,AP3S2,FOXN2,CNN2,MAP3K14,TMEM8A,SAMD4B,NTPCR,ERMP1,ACP2,WBP2,PFKFB3,MAP4K3,MEF2D,MCFD2,METTL22,SF3A2,ZDHHC3,HGS,FNTA,WAS,UAP1,GRIPAP1,ZNF330,H2AFX,ITGB1,USP20,FAM126A,CNOT6,GAS2,SMAD4,NUDT3 |
| 6.382e-05 | -9.66 | REACTOME_PHOSPHOLIPID_METABOLISM | MSigDB lists | REACTOME_PHOSPHOLIPID_METABOLISM | 188 | 49 | 17377 | 2626 |
CDS2,HEXB,CERK,AGPAT1,ASAH1,AGPAT3,SUMF1,CHKB,ARF1,CDIPT,LCLAT1,PIP4K2A,PIP5K1C,CHKA,PTEN,MTMR4,PIK3R2,SLC44A1,LPIN2,HADHB,PCYT2,PIKFYVE,LPCAT1,GPD1L,GM2A,CSNK1G2,GALC,PGS1,GBA,MTMR6,SUMF2,PNPLA8,PITPNB,ARSK,TAZ,NEU1,PI4K2A,MTMR3,PLD3,AGPAT2,CERS6,LPCAT4,CTSA,MBOAT1,SMPD4,PSAP,CHPT1,HEXA,PTDSS1 |
| 6.382e-05 | -9.66 | GSE17301_CTRL_VS_48H_IFNA2_STIM_CD8_TCELL_UP | MSigDB lists | GSE17301_CTRL_VS_48H_IFNA2_STIM_CD8_TCELL_UP | 188 | 49 | 17377 | 2626 |
MBD1,SLC12A7,IER2,TMBIM4,ASAH1,TM9SF3,EXT2,PAPOLA,AHCTF1,SIAH1,IL6ST,LPIN2,ZNF200,FAM89B,UBE3B,PIK3IP1,MINPP1,SCYL3,FAM171A1,EBAG9,ZDHHC18,CLCN3,PPP3CA,BIRC3,COQ10B,RAB7A,PIP4K2C,KRAS,MCL1,PLEC,ESYT1,PRMT2,PDE3B,NEU1,RDH11,UBTF,FBXO21,PFDN5,PPP2R5A,GOLGA7,CSK,OSBPL8,STAT6,MLYCD,LY75,DUSP11,NAA60,ZC3HAV1,TMEM131 |
| 6.382e-05 | -9.66 | GSE36476_YOUNG_VS_OLD_DONOR_MEMORY_CD4_TCELL_40H_TSST_ACT_DN | MSigDB lists | GSE36476_YOUNG_VS_OLD_DONOR_MEMORY_CD4_TCELL_40H_TSST_ACT_DN | 188 | 49 | 17377 | 2626 |
MBD1,WASF2,COMMD10,NCOR2,PRKAB1,TRIP12,MRPS15,UBR2,TSC22D3,RHOC,DAP,RAF1,BABAM1,LAGE3,ZFYVE21,MEF2A,EPHX2,EXT2,YY1AP1,CDK5,CALM2,ATP2A2,DAPK1,MAP3K14,METTL9,TALDO1,F2R,GCC1,ZNF189,ANKLE2,POLR2G,CREG1,ZNF202,MAP4K4,H2AFV,LUC7L,CDK11A,PI4K2A,PAF1,SEC31A,TPD52L2,PDCD6,TMEM168,MAGT1,STK38,GADD45B,COX8A,SSNA1,RNF114 |
| 6.382e-05 | -9.66 | GSE10325_MYELOID_VS_LUPUS_MYELOID_DN | MSigDB lists | GSE10325_MYELOID_VS_LUPUS_MYELOID_DN | 188 | 49 | 17377 | 2626 |
CDS2,TXN,PARP12,GNPDA1,FAM129A,ABCC10,ADO,TAP1,DHX8,CUL1,ADPGK,POMP,CDC73,HLA-A,SLC25A37,CALM2,PSMA6,SHC1,MED8,ATP2A2,SP100,ZCCHC2,DDA1,TFG,STAT3,GM2A,KDELR1,ADAM17,NRAS,ACP2,DPM1,GABPA,LAP3,DRAP1,MAP7D1,LY6E,EDEM2,PEF1,ISG15,NUCB1,CTBS,PROSER1,MAPK6,STAT1,GLG1,CTSA,RGL1,EHD4,IFI16 |
| 6.388e-05 | -9.66 | GSE24814_STAT5_KO_VS_WT_PRE_BCELL_DN | MSigDB lists | GSE24814_STAT5_KO_VS_WT_PRE_BCELL_DN | 193 | 50 | 17377 | 2626 |
FGFR1OP,GCLM,PPP1R12A,SRGN,REEP5,ABHD14A,APP,FANCI,EBP,HERC3,ZNF428,POP7,PPP6C,DAPK1,ATP6V0A2,CTR9,SLC38A10,CDC25B,TP53BP2,MAP3K14,CREB1,HNRNPM,ALDH9A1,NUDC,NIPSNAP1,FDFT1,SAP30,KDM3B,ERCC1,MAPRE2,AGGF1,ACSL3,MRPL12,ELP4,MTMR6,NFATC2IP,KLF6,PDE3B,STK17B,PAF1,KIF2A,SERTAD2,GOLGA8A,DCK,ACLY,PPP3R1,PDXK,ACADM,OAZ1,BYSL |
| 6.429e-05 | -9.65 | S-adenosylmethionine-dependent methyltransferase activity | molecular function | GO:0008757 | 156 | 43 | 17224 | 2647 |
ASH1L,DNMT3A,NOP2,KMT2E,CXXC1,SUZ12,NSD3,EZH1,WDR5,METTL3,IRF4,KMT5C,SUV39H2,KMT5A,METTL14,CMTR2,FBL,DNMT1,MRM3,NSUN4,FTSJ3,CARM1,MRM2,METTL1,HEMK1,EHMT1,NSUN2,METTL2A,ARMT1,WDR82,ICMT,METTL22,KMT2C,PRMT2,MEN1,DOT1L,SETD3,CAMKMT,WDR4,FTSJ1,KMT2B,PRMT7,TRMT10B |
| 6.477e-05 | -9.64 | IQGAP1 (IQ motif containing GTPase activating protein 1) | protein interactions | 8826 | 267 | 68 | 17029 | 2761 |
USP7,ADD1,LUZP1,ACTR3,RAC1,MYH9,UBE2I,SEC16A,PRKACA,MAPK14,GGPS1,DST,RAP1A,SHC1,CDC42,PPME1,PIK3R2,CLTB,DVL2,CFL1,CDC5L,CCT2,PPP1R18,EID1,EZR,NFATC2,BRCA1,DNAJA1,MCM2,CORO1C,MYO18A,ACTB,MAPK1,PPP2R2D,GOLIM4,PPP1R12A,MYL6B,RPA2,SMC3,AHSA1,ANXA5,GTSE1,MYO5A,CAMK2G,SPTAN1,STAU1,PPP1R9B,WDR1,OXR1,PSMA1,PLEC,CAPZA2,MEN1,MAP2K2,ECH1,DAPK3,ISG15,MAPK3,RPA1,SDHB,INF2,C1orf131,SYNCRIP,QARS,KBTBD7,RPS6KC1,CDK2,CDKN2A |
| 6.485e-05 | -9.64 | GOBERT_OLIGODENDROCYTE_DIFFERENTIATION_DN | MSigDB lists | GOBERT_OLIGODENDROCYTE_DIFFERENTIATION_DN | 994 | 194 | 17377 | 2626 |
PNISR,HNRNPAB,PLXNC1,PIGQ,ABCC10,SIRT2,MAP1LC3B,PPP1R16B,ELMOD2,CMTM6,ATPAF1,PRNP,LIN9,CDK5,DST,GLIS2,RABGAP1L,SLC44A1,HADHB,ZFYVE27,SLC26A2,ABCC5,PLK3,BAK1,DEAF1,ERCC1,RHOBTB3,GNG7,SLC16A7,GMFB,TMEM216,EZR,PLEKHM3,BRCA1,SLC17A5,ICMT,SOX4,CCNF,ZFAND5,RAB2B,DPYSL3,BRMS1,RAD18,CHD3,TPP2,MYO18A,OGT,MPV17,ACTB,PTPDC1,RNASEL,FBXL3,SASS6,CHPT1,PDCD4,SVIP,MAPRE1,ADO,TRIO,DLGAP4,SDC2,CIB1,CERK,MAN2B1,APOPT1,ATG4A,C4orf3,KLHL5,MBD2,PIGG,ATP6V0A2,GLTP,PIK3IP1,LUC7L2,CYTH1,PIGT,WDR1,AMD1,PIP4K2C,PLEC,CYFIP2,CYB5A,MASTL,SCARB2,GOLGA4,RBM25,ETS2,SETD3,USP32,APPL2,CABIN1,MAP3K5,RUFY3,C11orf1,TMEM14A,RHOG,TCF12,TRIM41,CORO7,CYLD,DNMT3A,REPS2,CKLF,DYNLL1,ANK3,KLHL18,TM9SF3,MXD1,ANKRD28,ZKSCAN1,TBC1D22A,MTMR4,TBC1D14,ADCY9,SOCS6,TTC3,LMAN1,ABI1,TMBIM1,CLCN3,ERMP1,TIMP2,MAPRE2,PPT1,NARF,FRAT2,CDCA2,CADM1,HERPUD2,ARL5B,H2AFV,ALDH3B1,PEX5,HSPA4,HNRNPR,CERS6,CORO1C,HIPK2,GADD45B,STAT1,RBMS1,MBOAT1,SLC22A23,GEN1,SMURF1,USP53,ATMIN,ATXN7L2,BCL2L12,MIF4GD,ZNF445,PKP4,GOLPH3L,CASP6,B4GALT5,MECP2,KLF13,CCDC28A,WWP2,TMCC3,HOMER1,ADD3,PDCD10,ITGB8,ATG13,LDLRAD3,SGCB,PACS2,IMPA2,MICAL3,RNF5,PDLIM2,NIPAL3,NASP,FAM49B,GALC,PSPC1,PPP1R21,KIAA0930,PRKAR1B,EMP3,RFFL,ZFR,HSPA1B,TFEB,DDX23,ACOX1,USP20,ARHGAP23,CD81,SAT2,TERF1,CPEB2,SNAPIN |
| 6.500e-05 | -9.64 | UBE2M (ubiquitin conjugating enzyme E2 M) | protein interactions | 9040 | 87 | 29 | 17029 | 2761 |
CPNE1,EWSR1,RBX1,CUL3,KLHL18,CUL1,KRAS,DCUN1D5,DCUN1D4,PCBP1,APP,BTBD1,PRDX1,LMNA,CAND1,MDM2,RAD18,KLHL20,KBTBD7,KHDC4,COPS7B,KLHL42,COPS6,CDK2,SMURF1,TERF1,UBE2M,PCBP2,CDC5L |
| 6.500e-05 | -9.64 | HIST1H1T (histone cluster 1 H1 family member t) | protein interactions | 3010 | 87 | 29 | 17029 | 2761 |
NOL12,YTHDC1,RPS15,ZCCHC9,CHERP,MECP2,RPS10,GTPBP4,DHX8,SREK1,BUD13,MCM2,BRIX1,TTF1,DHX57,ZNF92,KRR1,KRI1,DDX56,UPF1,CMSS1,U2SURP,H2AFX,RPF2,RRS1,ZC3HAV1,CCDC137,PRPF4B,DDX52 |
| 6.504e-05 | -9.64 | drug binding | molecular function | GO:0008144 | 1724 | 321 | 17224 | 2647 |
ABCC10,TAP1,DHX8,GLUD1,UBE2I,OAT,EEF2K,KIFC1,CDK5,NEK6,ATP13A3,PDS5B,SUCLG2,MAST2,PLK3,RHOBTB3,AKT2,PBK,KIF15,MKI67,DDX20,SMC2,AURKB,MCM2,RFC2,MAP3K4,MKNK1,KIF18B,LIMK1,MYO18A,RNASEL,LONP2,PFKP,DDX42,DDX58,HSPH1,RECQL,MUT,CHTF18,TRIO,PRKAA1,DHX9,RRM1,CERK,KIF23,TOP2B,EIF2AK4,METTL3,PDXDC1,FKBP1A,DDX56,CEP104,SMC3,MCM5,CTPS1,MSH2,DAPK1,RTCB,PIKFYVE,PHKG2,UBE2QL1,CARS2,DDX28,SIGMAR1,COQ8A,MAPKAPK3,DHX29,PGS1,PIP4K2C,PKM,MTR,ABCF1,MAP2K2,CCT8,PI4K2A,XRCC5,EPRS,NSF,CSK,CSNK1G1,DCK,QARS,ACLY,PPP3R1,MAP3K5,CDK2,NRBP1,ACSF2,KARS,ABCA3,TP53RK,RPS6KA1,RAF1,CHD1L,KIAA0232,ACTR3,OLA1,TPX2,MYH9,PRKACA,CBWD5,CD320,FLAD1,PRKD3,ATP2A2,UBA5,ADCY9,CLCN6,TAP2,AQR,CDK12,ADCY7,CCT2,ULK3,ATP13A1,MAP4K4,TAOK1,PFKFB3,GALK2,PKMYT1,DNAJA1,FKBP3,MAT2A,DHX57,DDX17,KIF2A,RAD51C,HSPA4,JAK1,HIPK2,CBWD1,PDXK,PPP5C,CSNK1D,DYNC1LI2,POLQ,PRPF4B,GALK1,TWNK,IP6K2,ATP5F1B,BLM,PMVK,PIP5K1C,SRXN1,GATC,CBWD2,SUV39H2,TTLL12,MAP3K14,UBE2M,MSH6,SMC4,PDPK1,PPP3CA,TK1,GUK1,DDX24,NEK7,BMS1,DDX39A,KIF11,MARK2,MYO1F,SLC19A1,KIF18A,TTLL4,MAPK6,HMGB2,ASNA1,DDX5,DDX52,DDX47,UBE2E2,YTHDC2,MCCC1,CSNK2A1,UBE2Q1,UBE2Z,ABCB10,KIF2C,FKBP2,MAPK14,PAPOLA,ABL2,GOT2,EIF4A3,METTL14,TRMU,XRCC2,KIF22,ABCC5,SRPK2,PLK1,LARS,SNRNP200,HARS,TLK1,CDC6,STK17B,DHX15,CHD3,IARS2,BAZ1B,QRSL1,ACTB,STK11,CHEK2,VPS4A,ROCK1,PSMC1,SEPHS2,UBE2D3,CDK13,PPP3CB,THRAP3,CHKA,UBE2Q2,KIF13B,GLE1,ALDH18A1,N4BP2,CSNK1G3,ABCC1,NTPCR,AACS,NQO2,ACSL3,MAP4K3,EIF2AK1,UBE4B,DAPK3,BBS12,MASTL,PSMC4,PRPS2,NLRC5,ATP5F1A,RUVBL2,MYO9A,EHD4,MMACHC,PMS2,UCK2,SMARCA4,UCK1,ORC1,CHKB,ATP6V1B2,TWF2,LYN,CHD1,FARSA,PDK2,IARS,NVL,KIF14,SCYL3,PPIF,ACSL5,CLCN3,CGAS,PGGT1B,PPIE,RAD54B,ATP1A1,IDE,CLK3,DHX16,STK38,FASTK,FKBP5,XRCC3,MAPK1,CHID1,ABCA1,RAD51D,KIF3B,NADSYN1,SHPRH,TOR3A,GNE,SCYL1,SMC6,MYO9B,CDK11B,CSNK1A1,SCYL2,PIP4K2A,XPR1,WRNIP1,KIF5B,STARD9,FGFR3,GART,GRK2,PPIG,ABCD1,DDX31,CAMK2G,MYO5A,CSNK1G2,PRKDC,HELB,BTAF1,ATP2C1,ABCF2,NADK2,PNPLA8,CDK11A,TARS,DDX23,HSPA1B,MAPK3,NEK1,UPF1,ATAD2,CTBS,RPS6KC1,UBE2C,HIPK3 |
| 6.516e-05 | -9.64 | oligosaccharyltransferase complex | cellular component | GO:0008250 | 12 | 8 | 18223 | 2701 |
RPN1,DDOST,MAGT1,STT3A,DAD1,RPN2,KRTCAP2,OSTC |
| 6.529e-05 | -9.64 | ubiquitin protein ligase activity | molecular function | GO:0061630 | 230 | 58 | 17224 | 2647 |
MIB2,TRIP12,SHPRH,TRIM11,UBR2,XIAP,UBE2Z,CBLL1,BRAP,CUL1,NHLRC3,UBE4A,ZNRF3,UBE2I,ANKIB1,WWP2,HERC3,FANCL,RNF121,MDM2,MED10,CDC42,SIAH1,ZNRF2,HUWE1,PPIL2,LTN1,RNF19A,UBE3B,UBE3C,RNF26,LRSAM1,UBE2M,RNF5,RLIM,PRPF19,LONRF3,RBX1,VHL,RNF25,CUL3,RFFL,ANAPC2,TOPORS,UBE2V1,SYVN1,UBE4B,RAD18,RNF38,UHRF2,PPP1R11,TRIM32,SMURF1,RNF14,UBE2C,RNF139,ZNF598,RNF114 |
| 6.530e-05 | -9.64 | PSMD1 (proteasome 26S subunit, non-ATPase 1) | protein interactions | 5707 | 126 | 38 | 17029 | 2761 |
CYLD,DCTN2,RACGAP1,BLM,PSMD9,SDHA,UBLCP1,RAD23A,PTPN2,PSMD2,MDM2,PSMA6,HUWE1,UCHL5,SEC24C,RAD23B,CRY2,ECD,CDC5L,TXNL1,PSMA8,CUL3,PSMB7,PSMA1,SYVN1,BRCA1,PSMB9,CDK11A,PSMB3,PSMC4,PPP2CA,DERL1,HLA-B,PSMD3,PSMD8,SMAD1,ECPAS,PSMC1 |
| 6.530e-05 | -9.64 | THRAP3 (thyroid hormone receptor associated protein 3) | protein interactions | 9967 | 126 | 38 | 17029 | 2761 |
SART1,COX15,CYLD,THOC1,IVNS1ABP,SUZ12,DHX9,CSNK2A1,PARK7,LMNA,SF3B2,EIF4A3,MCM5,PIN1,AHSA1,LUC7L2,HNRNPM,TERF2,SRPK2,SRSF11,SF3B6,RNPS1,SREK1,BCLAF1,PRPF3,VDAC1,LUC7L,CAND1,CLK3,DDX5,PSAP,H3F3A,SNRNP70,ARRB2,NKAPD1,SMURF1,POT1,SSRP1 |
| 6.535e-05 | -9.64 | mitochondrial electron transport, NADH to ubiquinone | biological process | GO:0006120 | 42 | 17 | 17256 | 2622 |
NDUFA5,NDUFV2,NDUFS1,NDUFB6,NDUFA4,NDUFA7,NDUFB1,NDUFS7,NDUFS4,NDUFV1,NDUFA2,NDUFB4,NDUFA11,NDUFS8,NDUFB9,NDUFS5,NDUFA3 |
| 6.568e-05 | -9.63 | TUBB4B (tubulin beta 4B class IVb) | protein interactions | 10383 | 144 | 42 | 17029 | 2761 |
NPHP4,CYLD,PHB2,SUMO2,CUL1,CDK13,ATP6V1B2,HAUS2,TUBGCP2,COPB2,MCTS1,RPA2,SHC1,PTEN,HUWE1,MCM5,AKAP8,SOCS6,LMAN1,CDC5L,VHL,CUL3,RPL8,PSMA1,BRCA1,MCM2,RAB1A,SOCS7,CAND1,RPA1,MAGED2,COPS6,CDK2,ARRB2,ECPAS,SMURF1,CD81,TERF1,POT1,TUBB,CDKN2A,PFKP |
| 6.600e-05 | -9.63 | pancreas-carcinoid-endocrine_tumour-vipoma | COSMIC cancer mutations | pancreas-carcinoid-endocrine_tumour-vipoma | 7 | 6 | 17385 | 2587 |
GNAS,KRAS,MEN1,PTEN,VHL,SMAD4 |
| 6.600e-05 | -9.63 | soft_tissue-fibrous_tissue_and_uncertain_origin-myxoma | COSMIC cancer mutations | soft_tissue-fibrous_tissue_and_uncertain_origin-myxoma | 7 | 6 | 17385 | 2587 |
GNAS,KRAS,FUS,EWSR1,NRAS,HRAS |
| 6.600e-05 | -9.63 | soft_tissue-fibrous_tissue_and_uncertain_origin-malignant_fibrous_histiocytoma-pleomorphic_sarcoma-myxoid | COSMIC cancer mutations | soft_tissue-fibrous_tissue_and_uncertain_origin-malignant_fibrous_histiocytoma-pleomorphic_sarcoma-myxoid | 7 | 6 | 17385 | 2587 |
RB1,KRAS,FUS,NRAS,PTEN,HRAS |
| 6.629e-05 | -9.62 | Nonsense-Mediated Decay (NMD) | REACTOME pathways | R-HSA-927802 | 120 | 37 | 10287 | 1696 |
RPS15,RPS2,RPLP2,GSPT2,RBM8A,RPL15,RPL11,RPL23A,EIF4A3,RPL17,DCP1A,RPL19,UPF2,RPL22L1,PABPC1,RPL29,RPL35,RNPS1,RPL8,RPL38,RPL6,RPS10,RPS24,RPL27A,RPS9,RPSA,RPL36,RPL37,PPP2CA,UPF1,RPL32,RPS27A,RPS14,RPLP1,SMG9,FAU,RPS26 |
| 6.629e-05 | -9.62 | Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) | REACTOME pathways | R-HSA-975957 | 120 | 37 | 10287 | 1696 |
RPS15,RPS2,RPLP2,GSPT2,RBM8A,RPL15,RPL11,RPL23A,EIF4A3,RPL17,DCP1A,RPL19,UPF2,RPL22L1,PABPC1,RPL29,RPL35,RNPS1,RPL8,RPL38,RPL6,RPS10,RPS24,RPL27A,RPS9,RPSA,RPL36,RPL37,PPP2CA,UPF1,RPL32,RPS27A,RPS14,RPLP1,SMG9,FAU,RPS26 |
| 6.659e-05 | -9.62 | Erh (ERH mRNA splicing and mitosis factor) | protein interactions | 13877 | 26 | 13 | 17029 | 2761 |
CHCHD3,ERH,INF2,FAM208B,PPP1R12A,RBMX,FLOT1,BCLAF1,THRAP3,CHTOP,DDX39A,FANCE,CHCHD6 |
| 6.659e-05 | -9.62 | LARP1B (La ribonucleoprotein domain family member 1B) | protein interactions | 55132 | 26 | 13 | 17029 | 2761 |
KIF2A,NIFK,RPS2,POLR2J,DGCR8,POC1A,GSPT2,H2AFX,CUL3,SNRNP70,ZC3H3,APP,LUC7L2 |
| 6.659e-05 | -9.62 | BRD3 (bromodomain containing 3) | protein interactions | 8019 | 26 | 13 | 17029 | 2761 |
UNK,BRD4,H2AFZ,BRD2,TACC1,UHRF2,BRD7,RUVBL2,MAP1LC3B,PIP4K2A,APP,SUPT16H,SRPK2 |
| 6.659e-05 | -9.62 | Espl1 (extra spindle pole bodies 1, separase) | protein interactions | 105988 | 26 | 13 | 17029 | 2761 |
CGAS,MECP2,VAV2,PTTG1,PML,NARF,DNAAF5,ARHGEF12,EFL1,CCNB1,MRM3,ESPL1,DOT1L |
| 6.730e-05 | -9.61 | IRE1-mediated unfolded protein response | biological process | GO:0036498 | 58 | 21 | 17256 | 2622 |
SEC61B,ADD1,SEC61G,CXXC1,SYVN1,SERP1,DNAJB9,LMNA,SSR1,SEC31A,YIF1A,SEC61A1,SHC1,TATDN2,ASNA1,MYDGF,PDIA6,ATP6V0D1,CTDSP2,PREB,DCTN1 |
| 6.730e-05 | -9.61 | regulation of chromosome separation | biological process | GO:1905818 | 58 | 21 | 17256 | 2622 |
PLK1,ZNF207,CDT1,CENPF,PTTG1,CUL3,CSNK2A1,CDC6,CCNB1,CDC23,MAD2L2,RB1,CDC27,NEK6,NSMCE2,XRCC3,UBE2C,GEN1,ESPL1,ANAPC4,TACC3 |
| 6.746e-05 | -9.60 | KINESINHEAVY | prints domains | PR00380 | 44 | 14 | 4652 | 473 |
KIF2A,KIFC1,KIF5B,STARD9,KIF3B,KIF18A,KIF18B,KIF13B,KIF14,KIF15,KIF23,KIF22,KIF2C,KIF11 |
| 6.769e-05 | -9.60 | TMEM216 (transmembrane protein 216) | protein interactions | 51259 | 243 | 63 | 17029 | 2761 |
NDC1,TOR1AIP1,GPR89A,TMX4,TMEM109,CDCA3,AGPAT1,CLCC1,STAM,PDXDC1,APP,KTN1,BCAP31,TFRC,FZD6,SSR1,DDRGK1,PTPN2,SEC11A,VMP1,CISD2,LMAN1,SLC12A2,LRRC59,LPCAT1,RHBDD2,SCYL3,TMEM9,NCOA2,TMX1,PREB,EBAG9,WDR41,CHP1,ANKLE2,TMEM115,GOPC,NSDHL,RAB7A,ACSL3,LRBA,ATP6V0A1,TOR1AIP2,NUP155,GORAB,GORASP2,PKMYT1,ESYT1,GOSR1,LSG1,BSDC1,SLC19A1,PLD3,OSBPL11,SEC23IP,WDR11,OSBPL8,SNAP23,STX18,ITGB1,SMPD4,SPCS3,SCARB1 |
| 6.777e-05 | -9.60 | Fcgamma receptor (FCGR) dependent phagocytosis | REACTOME pathways | R-HSA-2029480 | 86 | 29 | 10287 | 1696 |
WASF2,CYFIP1,NCK1,ACTR3,VAV2,RAC1,MYH9,WIPF1,MYO9B,NCKAP1,CYFIP2,ARPC1A,LYN,PLPP5,MAPK3,VAV1,PLD3,WAS,CDC42,ARPC5,ELMO1,LIMK1,PIK3R2,ACTB,AHCYL1,MAPK1,ABI1,CFL1,MYO5A |
| 6.790e-05 | -9.60 | UFM1 (ubiquitin fold modifier 1) | protein interactions | 51569 | 83 | 28 | 17029 | 2761 |
MIF,UBE2D3,TP53RK,CSRP1,MDH2,UFC1,UBXN1,MRPL12,TKT,ARHGDIB,RANGAP1,UBE4B,EFL1,PKM,VDAC1,SPR,NPLOC4,BCAT2,VASP,RAD23B,UBA5,PPA2,TTLL12,AHCYL1,PITRM1,S100A6,CFL1,USP34 |
| 6.790e-05 | -9.60 | UBA2 (ubiquitin like modifier activating enzyme 2) | protein interactions | 10054 | 83 | 28 | 17029 | 2761 |
SEPHS2,UNK,FOXK1,SUMO2,PSMA1,UBQLN2,PKM,BRIX1,ATP6V1B2,UBE2I,PARK7,PSMB3,NPLOC4,CLNS1A,SRXN1,DERL1,NAP1L1,WAS,CLIC4,WDR11,THADA,RAD23B,TTC9C,EHD4,AHCYL1,PDLIM5,TACC3,USP34 |
| 6.806e-05 | -9.60 | GO_ESTABLISHMENT_OF_PROTEIN_LOCALIZATION_TO_ENDOPLASMIC_RETICULUM | MSigDB lists | GO_ESTABLISHMENT_OF_PROTEIN_LOCALIZATION_TO_ENDOPLASMIC_RETICULUM | 102 | 31 | 17377 | 2626 |
SRP72,RPS15,RPL29,RPS2,RPL35,RPLP2,SEC61G,RPS10,RPL6,RPL38,RPL8,RPL15,RPS24,RPL27A,RPS9,RPSA,RPL11,RPL36,RPL23A,RPL37,CHMP4A,SEC61A1,RPL32,RPS27A,RPL17,RPS14,RPLP1,RPL19,CHMP4B,FAU,RPS26 |
| 6.829e-05 | -9.59 | HIST1H2BB (histone cluster 1 H2B family member b) | protein interactions | 3018 | 51 | 20 | 17029 | 2761 |
CYLD,EID1,SUZ12,CHD1L,DHX9,MCM2,APP,PHF6,LMNA,DOT1L,CHD3,MCM5,WDR4,ZNF746,PPM1G,H2AFY,CDK2,CD81,CBX4,SSRP1 |
| 6.829e-05 | -9.59 | ARF4 (ADP ribosylation factor 4) | protein interactions | 378 | 51 | 20 | 17029 | 2761 |
UNK,STAU1,BABAM1,CUL3,LDHA,ARF1,ADRB2,MCM2,DUSP22,CDC73,PTEN,ACADM,CLN3,CDK2,ATF2,CFL1,PCBP2,CDC5L,FUBP1,LDHB |
| 6.829e-05 | -9.59 | SRSF4 (serine and arginine rich splicing factor 4) | protein interactions | 6429 | 51 | 20 | 17029 | 2761 |
SART1,STAU1,ZMYND11,SRSF6,CUL3,RNPS1,SREK1,CUL1,SF3A2,LMNA,SRSF1,CAND1,WRNIP1,EIF4A3,TRA2B,TICAM1,FUS,SMURF1,CDC5L,SRSF10 |
| 6.853e-05 | -9.59 | transcription elongation from RNA polymerase II promoter | biological process | GO:0006368 | 97 | 30 | 17256 | 2622 |
CTDP1,POLR2I,POLR2G,POLR2L,POLR2K,ELL2,ELOA,POLR2D,ELP4,CDK13,RTF1,PBRM1,EAF2,CDC73,POLR2A,GTF2F1,SUPT16H,IWS1,TAF2,PAF1,CCNK,POLR2J,CTR9,TAF12,TCEA1,TAF6,GTF2H2,CDK12,SSRP1,ELOF1 |
| 6.859e-05 | -9.59 | PASQUALUCCI_LYMPHOMA_BY_GC_STAGE_DN | MSigDB lists | PASQUALUCCI_LYMPHOMA_BY_GC_STAGE_DN | 154 | 42 | 17377 | 2626 |
CORO7,CKLF,GMFG,TOP2B,SNN,ZADH2,ETS1,CHD1,SLC25A37,JAKMIP1,PHC2,CDKN2C,NUDT19,CCDC50,RCSD1,ZCCHC2,CORO1A,CNOT6L,SMARCE1,GPD1L,MTPN,SNX2,EMB,LACTB,DNAJC9,FRAT2,ARHGDIB,CYFIP2,CBFB,PDE3B,BTBD1,RBM38,ARHGAP15,SRSF1,SH3BP5,HHEX,NAP1L1,WAS,PDLIM1,SYNCRIP,ANP32E,E2F2 |
| 6.881e-05 | -9.58 | EIF4G1 (eukaryotic translation initiation factor 4 gamma 1) | protein interactions | 1981 | 100 | 32 | 17029 | 2761 |
UNK,MRPL9,CYLD,TOR1AIP1,CNTROB,PABPC4,ANXA5,UPF2,TARDBP,FBL,EIF5,PABPC1,HTRA2,SRPK2,FTL,CUL3,SLBP,USP10,BRCA1,NFATC2IP,MCM2,EIF4G2,SF3A2,EIF3A,EIF3H,CENPU,ISG15,MKNK1,POLE,QARS,ZC3H7B,PDCD4 |
| 6.889e-05 | -9.58 | TTTGTAG,MIR-520D | MSigDB lists | TTTGTAG,MIR-520D | 323 | 75 | 17377 | 2626 |
WASF2,ADD1,ALKBH5,UBQLN2,FBXO22,ATP2A2,JAZF1,MTA1,METTL9,LRRC59,TIPARP,SEH1L,RLIM,ELOF1,SP3,LRBA,ATXN1,LUC7L,ODC1,STK17B,EIF3A,CLNS1A,SRSF1,DDX17,ANKRD10,PPP2CA,RBM47,BRWD1,TAB2,LUC7L3,ARRDC1,H3F3A,ABCA1,CBX4,PDCD4,PRPF4B,PRPF38B,SRSF6,MECP2,SESTD1,SDC2,CTCF,ARGLU1,PRPF39,TMEM165,ETS1,PTPN2,FKBP1A,LRRC8D,DAPK1,TPST1,UBE3C,CITED2,PIKFYVE,HNRNPM,KDELR1,SOCS5,MORC3,TSHZ1,PPP3CA,MIER1,SRSF5,KIF11,EIF4G2,CCT8,PHF6,BSDC1,CAND1,CBX3,FNTA,SERTAD2,VCPIP1,SLAIN1,PURA,CPEB2 |
| 6.890e-05 | -9.58 | regulation of ubiquitin-protein transferase activity | biological process | GO:0051438 | 54 | 20 | 17256 | 2622 |
PLK1,RPS2,GORASP1,TOPORS,DCUN1D5,RAB1A,DCUN1D4,PSEN1,PARK7,MAD2L2,ZER1,FBXO5,RPL11,GOLGA2,PTEN,PIN1,AXIN1,LIMK1,FEM1B,UBE2C |
| 6.890e-05 | -9.58 | regulation of mitotic sister chromatid separation | biological process | GO:0010965 | 54 | 20 | 17256 | 2622 |
PLK1,ZNF207,CDT1,CENPF,PTTG1,CUL3,CDC6,CCNB1,CDC23,MAD2L2,RB1,CDC27,NEK6,NSMCE2,XRCC3,UBE2C,GEN1,ESPL1,ANAPC4,TACC3 |
| 6.890e-05 | -9.58 | GO_ATPASE_BINDING | MSigDB lists | GO_ATPASE_BINDING | 71 | 24 | 17377 | 2626 |
ATXN3,UBXN1,TOR1AIP1,EZR,ATP6V0A1,TOR1AIP2,SDF2L1,UBE4B,DNAJB1,SYVN1,DERL1,DNAJC10,CHMP4A,RALB,ZNHIT6,RAB4A,NSFL1C,ATP6V0A2,PKD2,RUVBL2,FBL,ABCA1,SVIP,ATP6V1G1 |
| 6.890e-05 | -9.58 | GO_SINGLE_ORGANISM_MEMBRANE_BUDDING | MSigDB lists | GO_SINGLE_ORGANISM_MEMBRANE_BUDDING | 71 | 24 | 17377 | 2626 |
USO1,TRAPPC9,GORASP1,CUL3,MCFD2,RAB1A,SEC16A,ANKRD28,CD59,SEC31A,SEC23IP,GOLGA2,NSF,TMED10,SEC24C,MYO18A,PPP6C,PPP6R3,LMAN1,TFG,PPP6R1,CSNK1D,TMED2,PREB |
| 6.890e-05 | -9.58 | GO_SWI_SNF_SUPERFAMILY_TYPE_COMPLEX | MSigDB lists | GO_SWI_SNF_SUPERFAMILY_TYPE_COMPLEX | 71 | 24 | 17377 | 2626 |
PHF10,ARID2,MTA2,CSNK2A1,SMARCA4,ARID1A,INO80E,PBRM1,MBD3,ARID1B,APPL1,RB1,CHD3,UCHL5,APPL2,BRD7,ANP32E,SS18L1,RUVBL2,YY1,RBBP4,SMARCE1,HDAC2,SMARCD1 |
| 7.003e-05 | -9.57 | GSE19888_ADENOSINE_A3R_ACT_VS_TCELL_MEMBRANES_ACT_IN_MAST_CELL_DN | MSigDB lists | GSE19888_ADENOSINE_A3R_ACT_VS_TCELL_MEMBRANES_ACT_IN_MAST_CELL_DN | 159 | 43 | 17377 | 2626 |
RMND5A,RAB14,IER2,GGNBP2,DNMT3A,TMUB1,SF3B1,WDTC1,S1PR2,SLC25A43,SF3B2,AHCTF1,HDAC7,ARHGEF1,FEM1B,ANP32A,TAGLN2,ZNF800,APH1A,MBLAC2,RAB7A,RFFL,AP4E1,API5,PATL1,EIF3A,USP36,PRDM11,KIF2A,UTP20,HGS,MID1IP1,WDR11,GOLGA2,RBL1,OSBPL8,CBLN2,TAF6,COIL,SMAD4,IPO4,GPATCH4,NUMB |
| 7.004e-05 | -9.57 | SESN2 (sestrin 2) | protein interactions | 83667 | 14 | 9 | 17029 | 2761 |
MDM2,KEAP1,RBX1,RB1CC1,WDR59,ATG13,WDR5,DHX57,PRDX1 |
| 7.026e-05 | -9.56 | Resolution of Sister Chromatid Cohesion | REACTOME pathways | R-HSA-2500257 | 103 | 33 | 10287 | 1696 |
MAPRE1,CENPF,CDCA8,NUF2,KIF2C,PMF1,CCNB1,SPDL1,MIS12,SMC3,AHCTF1,NUP107,PDS5B,KNTC1,CENPM,NUP85,SEH1L,NUDC,PLK1,TAOK1,RANGAP1,AURKB,CENPU,PPP2CA,KIF2A,KIF18A,DSN1,PPP2R5A,BIRC5,CDCA5,CENPT,NDE1,CCNB2 |
| 7.048e-05 | -9.56 | Bromodomain | pfam domains | PF00439 | 39 | 16 | 17054 | 2545 |
ASH1L,BRD4,KAT2A,BAZ2A,ZMYND11,SMARCA4,PBRM1,BRD2,SP100,BRWD1,BRPF3,ATAD2,BAZ1B,BRD7,BRWD3,BRD9 |
| 7.049e-05 | -9.56 | CYC1 (cytochrome c1) | protein interactions | 1537 | 79 | 27 | 17029 | 2761 |
COX15,PHB2,UQCR10,TAP1,VDAC2,NDUFA4,CYCS,MTMR12,OGDH,TOMM40,RAB1A,VDAC1,SDHA,NDUFS4,SSR1,RPN1,ATP1A1,ZNF746,COX5A,UQCRH,NDUFS8,ATP5F1A,CYC1,CLN3,LMAN1,ATF2,EYA2 |
| 7.066e-05 | -9.56 | condensed chromosome kinetochore | cellular component | GO:0000777 | 104 | 31 | 18223 | 2701 |
PLK1,ZNF207,SKA3,HJURP,CDT1,CENPF,NUF2,RANGAP1,KIF2C,PMF1,CCNB1,SEPT7,SPDL1,CSNK1A1,MEAF6,MIS12,SPAG5,PHF6,CENPU,AHCTF1,DSN1,FBXO28,BIRC5,NUP107,SS18L1,CENPM,CENPT,KNTC1,NDE1,NUP85,SEH1L |
| 7.104e-05 | -9.55 | HSPE1 (heat shock protein family E (Hsp10) member 1) | protein interactions | 3336 | 122 | 37 | 17029 | 2761 |
PPIB,UNK,PTMS,HSPH1,EWSR1,TXN,UGP2,TKT,SPR,FKBP1A,PIN1,AHSA1,UBA5,AKR1B1,TAGLN2,CLTB,TALDO1,ATF2,IMPA2,CFL1,GPX4,PPIF,CCT2,WDR1,EZR,GLO1,HAGH,CBX3,CAT,ADSS,HSPA4,CHMP4A,HINT1,ZHX1,DCK,DBI,CDK2 |
| 7.104e-05 | -9.55 | CALU (calumenin) | protein interactions | 813 | 122 | 37 | 17029 | 2761 |
TP53RK,RAF1,ACTR3,TKT,CSNK2A1,CNTROB,UBQLN2,UBE2I,PRKACA,TMEM165,EEF2K,PTPN2,RPA2,PCNA,GTSE1,CDC25B,PTGES3,ATF2,RPRD1B,HARS,ASPM,NSUN2,PRKAR1B,RANGAP1,MCM2,ARPC1A,MTR,SH3GLB1,TPD52L2,DUS3L,RPL32,EIF2D,IARS2,SH3GLB2,XRCC3,CLN3,PDLIM5 |
| 7.121e-05 | -9.55 | GSE37532_VISCERAL_ADIPOSE_TISSUE_VS_LN_DERIVED_PPARG_KO_TREG_CD4_TCELL_UP | MSigDB lists | GSE37532_VISCERAL_ADIPOSE_TISSUE_VS_LN_DERIVED_PPARG_KO_TREG_CD4_TCELL_UP | 164 | 44 | 17377 | 2626 |
C9orf78,FEZ2,MANBA,RRM1,MYH9,NIT2,CDC42SE2,GYG1,TUBGCP2,MXD1,HDDC2,PA2G4,MLX,RBM34,IMPAD1,ARL6IP1,SRI,EI24,MTX2,TSHZ1,STAU1,RFC3,FAM49B,TSPYL4,PBK,MTA2,GOPC,PIP4K2C,USP10,VDAC1,ANLN,ODC1,KLF6,SMAP2,BTBD1,ANKRD10,WDR76,TAF12,NAA20,TMEM14A,IGBP1,ZMAT3,ZC3HAV1,SMARCD1 |
| 7.144e-05 | -9.55 | ACEVEDO_NORMAL_TISSUE_ADJACENT_TO_LIVER_TUMOR_DN | MSigDB lists | ACEVEDO_NORMAL_TISSUE_ADJACENT_TO_LIVER_TUMOR_DN | 334 | 77 | 17377 | 2626 |
PTMS,UROD,TMEM97,UCK1,GLUD1,SND1,OAT,EEF2K,SEC11A,GOT2,TBC1D14,LPIN2,NSFL1C,TECR,SPTSSA,PRADC1,PCBP2,CLPTM1,ZNF672,TRIM8,MAPRE2,APH1A,COQ10B,OAF,PSMB7,WBP2,SLC25A22,LRP5,DNAJA1,CADM1,RAB1A,RAB5B,SLC50A1,EML4,AGPAT2,VPS26B,CERS6,ZNF689,PRDX5,STK11,PDXK,CENPBD1,H3F3A,OAZ1,CMAS,COX5B,CDK2AP2,VAV2,MRPS26,ABHD14B,GTF3A,MXD4,SLC35B1,MYL6B,SNRNP25,MEA1,AHCY,RPL19,SLC25A1,TMEM160,SPTAN1,MAPKAPK3,NSDHL,ERLIN1,EIF2AK1,HAGH,SDHB,NUCB1,ZNF180,KPNA1,CSK,ZNF330,QARS,FN3KRP,NUP62,NUDT3,ZNF511 |
| 7.187e-05 | -9.54 | DBNL (drebrin like) | protein interactions | 28988 | 55 | 21 | 17029 | 2761 |
CMAS,RB1CC1,ERO1A,CUL1,RANGAP1,AGFG1,TERF2IP,RBM23,HOMER1,HSPBP1,GPS2,PPME1,WDR4,UBA5,OGT,USP20,DDX5,LRSAM1,TERF1,POT1,CFL1 |
| 7.187e-05 | -9.54 | Ppp2ca (protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform) | protein interactions | 19052 | 55 | 21 | 17029 | 2761 |
MOB4,CCT2,ZCCHC9,STRIP1,CIC,ZFP91,ZMYND11,TMEM109,STRN4,SIKE1,ATP5MF,CDC73,CCT8,C1orf131,KEAP1,CCDC6,INTS1,PPP4R1,INTS12,IGBP1,FGFR1OP2 |
| 7.201e-05 | -9.54 | GO_CYTOSKELETON_ORGANIZATION | MSigDB lists | GO_CYTOSKELETON_ORGANIZATION | 775 | 156 | 17377 | 2626 |
FGFR1OP,NPHP4,ADD1,NF1,XIAP,KIF2C,AGFG1,CNTROB,S1PR2,CCNB1,BIRC2,KIFC1,CDK5,DST,NEK6,CDC42,SYNM,DPYSL2,DNAAF2,XRCC2,RP2,MAST2,TACC3,PLK3,PLK1,NCK1,FOPNL,EZR,AURKB,BRCA1,ANLN,EPB41,DPYSL3,ZMYM3,WAS,BRWD1,KIF18B,CHD3,LIMK1,AXIN1,MAP4,MYO18A,ITGB1,CHEK2,ROCK1,VPS4A,DVL1,SASS6,PPP1R12A,CIB1,KIF23,MEF2A,RACGAP1,HAUS4,ITGB5,HAUS2,SPAG5,LMNA,JMY,CFLAR,PDXP,VASP,SMC3,CCP110,ARPC5,BCL2,ZRANB1,GCC2,WDR1,CAMSAP1,MYBL2,KRAS,MAP7D1,ARPC1A,HAUS8,PCM1,GOLGA2,ARAP1,SLC16A1,RUFY3,NDE1,CDK2,RHOG,ZNF207,WASF2,ATXN3,CORO7,TRIP10,RAF1,DYNLL1,RAC1,ANK3,ACTR3,TPX2,MYH9,STMN1,SHC1,KIF14,RNF19A,CEP63,CORO1A,ABI1,CFL1,PSRC1,MKLN1,BIRC3,TUBGCP5,CUL3,WIPF1,NUSAP1,BICD2,KIF2A,CORO1C,TRIM32,TUBB,CSNK1D,DYNC1LI2,KIF3B,EYA1,DCTN2,ARFIP2,PAWR,ARF1,CSNK1A1,RAB11A,TUBGCP2,MAD2L2,PIP5K1C,FBXO5,STARD9,PDCD10,KLHL20,CENPJ,PRC1,ARHGEF2,CNN2,TTC17,MICAL3,SPTAN1,PDPK1,PPP1R9B,RHOA,TACC1,ASPM,NEK7,ATP2C1,WDR81,KIF11,INF2,KIF18A,BIRC5,ELMO1,PKD2,WDR62,BRWD3,ESPL1 |
| 7.215e-05 | -9.54 | GSE21670_UNTREATED_VS_IL6_TREATED_CD4_TCELL_UP | MSigDB lists | GSE21670_UNTREATED_VS_IL6_TREATED_CD4_TCELL_UP | 169 | 45 | 17377 | 2626 |
TMUB1,DNAJB2,AGPAT1,SLC4A2,CNTROB,INO80E,NCKAP1,MXD4,CDIPT,RGS2,PPP1R16B,QSOX2,APP,HLA-A,FBXO5,C2orf68,COQ4,CCDC50,KLF16,INTS1,JAZF1,TOP1MT,TRIM14,PREB,ANKLE2,AMPD2,ZNF672,UBQLN4,TNFAIP3,KAT2A,CSRP1,ATG9A,MAPKAPK3,NEK7,AKT2,OAF,PFKFB3,RANGAP1,PRPSAP1,PEF1,POLR2J,JAK1,NCOA1,CAPN1,SMNDC1 |
| 7.217e-05 | -9.54 | PSMA2 (proteasome subunit alpha 2) | protein interactions | 5683 | 131 | 39 | 17029 | 2761 |
USP7,DCTN2,CUL1,POMP,UBQLN2,RAD23A,KIF5B,PSMD2,PSMD1,CLIC4,PSMA6,HUWE1,UCHL5,FBXO7,RAD23B,YBX1,UBE3C,CDC5L,PRPF19,PLK1,EXOSC6,RBX1,PSMA8,PSMB7,PSMA1,PSMG1,EXOSC9,SYVN1,PSMB9,PSMB3,CAND1,PSMC4,WDR11,PSMD3,PSMD8,ASNA1,ECPAS,PSMC1,TERF1 |
| 7.272e-05 | -9.53 | acetabulum | COSMIC cancer mutations | acetabulum | 5 | 5 | 17385 | 2587 |
GNAS,RB1,EWSR1,HRAS,CDKN2A |
| 7.272e-05 | -9.53 | haematopoietic_and_lymphoid_tissue-mouth-lymphoid_neoplasm-Burkitt_lymphoma | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-mouth-lymphoid_neoplasm-Burkitt_lymphoma | 5 | 5 | 17385 | 2587 |
RB1,KRAS,NRAS,HRAS,CDKN2A |
| 7.272e-05 | -9.53 | haematopoietic_and_lymphoid_tissue-abdomen-lymphoid_neoplasm-Burkitt_lymphoma | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-abdomen-lymphoid_neoplasm-Burkitt_lymphoma | 5 | 5 | 17385 | 2587 |
RB1,KRAS,NRAS,HRAS,CDKN2A |
| 7.286e-05 | -9.53 | GSE1460_DP_THYMOCYTE_VS_THYMIC_STROMAL_CELL_UP | MSigDB lists | GSE1460_DP_THYMOCYTE_VS_THYMIC_STROMAL_CELL_UP | 174 | 46 | 17377 | 2626 |
EXOC3,PRPF38B,SART1,LIME1,GPR132,THOC1,SUCLG1,SF3B1,CENPF,FAM76A,ACAP1,SMARCA4,MEF2A,SIKE1,CCNL2,SLC25A44,DAZAP2,PMVK,KIFC1,FAM192A,TNFAIP8,XRCC2,SRSF4,EXOSC1,KIF22,GNAI2,ILKAP,NOL12,MKLN1,PGS1,TEX10,MFNG,MTMR12,GALNT7,PPWD1,PRPF3,KCNQ1,SYMPK,ZMYM3,KIF2A,INF2,ZNF862,ACOX1,SAFB,NGLY1,IFI16 |
| 7.328e-05 | -9.52 | PSMB4 (proteasome subunit beta 4) | protein interactions | 5692 | 96 | 31 | 17029 | 2761 |
PLK1,USP7,PSMA8,PSMB7,PSMA1,CUL1,PSMG1,POMP,SYVN1,PSMD9,PSMB9,APP,PSMB3,PSMC4,RAD23A,HNRNPA2B1,KIF5B,PSMD2,PSMD1,PSMA6,CLIC4,UCHL5,PSMD8,PSMD3,FBXO7,H2AFX,YBX1,SMAD1,PSMC1,OAZ1,PRPF19 |
| 7.328e-05 | -9.52 | BCLAF1 (BCL2 associated transcription factor 1) | protein interactions | 9774 | 96 | 31 | 17029 | 2761 |
UNK,CYLD,THOC1,SUZ12,CUL3,CSNK2A1,THRAP3,BCL2L1,FXR1,CCNB1,LUC7L,CHD1,PARK7,RPS9,CAND1,CDKN2AIPNL,CLK3,PIN1,AHSA1,UHRF2,TARDBP,BCL2,SNRNP70,CHTOP,ZMIZ1,CDK2,ARRB2,SMURF1,CDK12,LUC7L2,SRPK2 |
| 7.334e-05 | -9.52 | regulation of organelle assembly | biological process | GO:1902115 | 188 | 49 | 17256 | 2622 |
TBC1D12,CHMP2A,FEZ2,PDCD6IP,CYLD,PHF23,KCTD17,TBC1D13,UBQLN2,BECN1,STAM,PIP4K2A,SPAG5,SMC3,CCP110,RALB,TBC1D22A,CENPJ,TBC1D14,ATG3,DNM2,ARHGEF2,PIKFYVE,CNOT6L,LRSAM1,RNF5,PLK1,RHOA,SEPT9,KAT2A,TCTEX1D2,PIP4K2C,EZR,BRCA1,SEPT7,CHMP2B,SH3GLB1,HSPA1B,MTMR3,TBC1D17,CHMP4A,MAP4,STX18,ATXN2L,NUP62,CHMP4B,CNOT6,SMAD4,ATMIN |
| 7.334e-05 | -9.52 | GSE41087_WT_VS_FOXP3_MUT_ANTI_CD3_CD28_STIM_CD4_TCELL_DN | MSigDB lists | GSE41087_WT_VS_FOXP3_MUT_ANTI_CD3_CD28_STIM_CD4_TCELL_DN | 179 | 47 | 17377 | 2626 |
COX5B,MDH2,PTTG1,C5orf30,GYG1,NCAPG,STMN1,APH1B,CPNE3,FANCI,SPAG5,CD59,RALB,SUCLG2,RPN2,ALDH18A1,GPD1L,MTX2,GM2A,NIPSNAP1,TMEM160,TK1,HEMK1,TIMP2,ACP2,LAP3,SELPLG,RAD51AP1,MKI67,HEBP2,GALK2,ADRB2,ANKRD46,PRDX1,RAD54B,MOSPD3,ATP6V1D,DSN1,SETD3,TFDP1,WDR7,UQCRH,TRIM32,PREPL,CCNB2,RAB3IL1,TMEM33 |
| 7.334e-05 | -9.52 | GSE20152_SPHK1_KO_VS_HTNFA_OVEREXPRESS_ANKLE_DN | MSigDB lists | GSE20152_SPHK1_KO_VS_HTNFA_OVEREXPRESS_ANKLE_DN | 179 | 47 | 17377 | 2626 |
IMMT,CASP6,TMX4,NENF,GTF3A,GGA2,XPO7,RMI1,STAM,SNAPC4,NUP205,PCYOX1L,DDX56,CCNA2,NVL,CENPJ,TRMU,EI24,TNPO3,SS18L1,PCYT2,CORO1A,POLR1B,ACAD8,MAML1,PDIA6,SLC35A1,ABCC5,NUDC,DDX28,AGGF1,AATF,CSRP1,KAT7,ESYT1,VDAC1,ZNF174,ADSS,DTWD1,TRIM26,MID1IP1,NEIL3,ARNTL,NAGLU,KHSRP,ZNF45,SSRP1 |
| 7.337e-05 | -9.52 | WANG_TUMOR_INVASIVENESS_DN | MSigDB lists | WANG_TUMOR_INVASIVENESS_DN | 199 | 51 | 17377 | 2626 |
COMMD10,KARS,PPP1R12A,RAB11B,IVNS1ABP,SCYL1,HABP4,B4GALT1,RACGAP1,JMJD6,ARF1,ATP6V1B2,MYEF2,MRPL19,SSR1,APLP2,BUD31,TTC3,MDFIC,TCEA1,PTGES3,POLR1B,GNAI2,GM2A,RLIM,NRAS,PBXIP1,CDC123,BTG2,WDR1,CPOX,MFNG,ILF3,ESYT1,LY6E,SLC50A1,EIF3G,DHX15,CBX3,PLAA,SEC61A1,CORO1C,LUC7L3,PML,MPV17,YWHAZ,RBPJ,UBE2C,TERF1,PPP2R2D,DYNC1LI2 |
| 7.363e-05 | -9.52 | GSE20715_0H_VS_48H_OZONE_LUNG_DN | MSigDB lists | GSE20715_0H_VS_48H_OZONE_LUNG_DN | 194 | 50 | 17377 | 2626 |
HSPH1,GCLM,RPS2,LUZP1,UBR2,DYNLL1,RRM1,DHX8,DNAJB1,SLC35B1,PMVK,STAM,ABHD14A,DNAJB9,SEC11A,PA2G4,CCNA2,VMP1,MCM5,AHSA1,DAPK1,PRC1,RBM15,ZC3H3,PPA1,TSHZ1,TK1,MLEC,SEC61B,NASP,ERLIN1,PBK,LDHA,SLBP,RRM2,KRAS,NUSAP1,DNAJA1,FXR1,ANLN,ASF1B,PRIM1,SYNCRIP,RBM47,CEP55,H2AFX,FKBP5,SPCS3,UBE2C,YWHAH |
| 7.363e-05 | -9.52 | GSE14769_UNSTIM_VS_120MIN_LPS_BMDM_DN | MSigDB lists | GSE14769_UNSTIM_VS_120MIN_LPS_BMDM_DN | 194 | 50 | 17377 | 2626 |
IER2,GPR132,B4GALT5,SRGN,ARID5A,PLAGL2,RNF103,SLC25A37,IRF4,VASP,CLIC4,LPIN2,SLC44A1,TANK,CITED2,TIPARP,CDK12,ZNF800,SOCS5,SAP30,ADAM17,NCK1,ELL2,TMEM39A,MAPKAPK3,COQ10B,OAF,ANKRD33B,BTG2,MKI67,RFFL,MCL1,MTMR12,MAP4K3,SERP1,MARK2,ISG15,ARF4,IRF5,RHBDF2,OPTN,SOCS7,HLA-B,AHNAK,MAPK6,NFIL3,SIAH2,AKNA,RRS1,CLN3 |
| 7.363e-05 | -9.52 | GSE29618_PRE_VS_DAY7_POST_LAIV_FLU_VACCINE_BCELL_UP | MSigDB lists | GSE29618_PRE_VS_DAY7_POST_LAIV_FLU_VACCINE_BCELL_UP | 184 | 48 | 17377 | 2626 |
SLC12A7,SLC30A9,RHOG,HECA,GMFG,NOP2,GORASP1,CAST,ARID5A,MAP1LC3B,RBM4,LMNA,RAD23A,MOAP1,GNS,NUP210,KDM2A,NDUFB4,FAM89B,BCL2,SP3,ERCC1,NXT1,GUK1,RNF25,HTATIP2,ADSL,EMP3,PRPF3,CAPZA2,PLEC,H2AFV,LUC7L,IRF5,UPF1,MID1IP1,LSM6,TFE3,TULP3,CCDC69,VCPIP1,RBPJ,FAU,PPP5C,CLN3,NAA60,TERF1,ADNP2 |
| 7.363e-05 | -9.52 | GSE17721_LPS_VS_PAM3CSK4_4H_BMDC_DN | MSigDB lists | GSE17721_LPS_VS_PAM3CSK4_4H_BMDC_DN | 184 | 48 | 17377 | 2626 |
TCF12,MMACHC,TMED7,C19orf53,CKLF,SRSF6,SLC2A1,SNX15,B4GALT1,USP39,SIKE1,GLUD1,CDC42SE2,XPO7,SEC16A,REEP5,RPN1,C18orf32,SHC1,DAD1,RNASEK,LTN1,RPF2,TTC3,ZBTB22,RBM3,NFU1,PTGES3,MRPL40,ATF2,FGFR1OP2,ACSL5,HTATIP2,RCOR1,GALK2,UBE4B,MEF2D,NDUFA7,MCFD2,MBD3,CYB5A,SUPT16H,ARAP1,TMEM101,RRS1,ATP6V1C1,ZNF830,RAB3IL1 |
| 7.363e-05 | -9.52 | GSE43863_TH1_VS_TFH_MEMORY_CD4_TCELL_DN | MSigDB lists | GSE43863_TH1_VS_TFH_MEMORY_CD4_TCELL_DN | 184 | 48 | 17377 | 2626 |
WASF2,CYTIP,ZNF496,ADD1,TSC22D3,CDT1,ANKH,CERK,KLF13,SMC6,MYH9,CDC42SE2,ETS1,GIT2,MBD4,PHC2,ADD3,KDM2A,SH3BP1,RCSD1,ARHGEF1,CDKN1B,ABCD1,AFF1,CNN2,LRSAM1,CTDSP2,FRMD8,GM2A,ADCY7,POU2AF1,CSNK1G2,STAU1,TRIM8,TK1,PRIM2,ZMYM5,PARP4,WDR81,PLEC,PDE3B,STK17B,MAN2A2,HHEX,SCARB2,HGS,CTSA,ABCA1 |
| 7.363e-05 | -9.52 | GSE557_WT_VS_I_AB_KO_DC_DN | MSigDB lists | GSE557_WT_VS_I_AB_KO_DC_DN | 184 | 48 | 17377 | 2626 |
HSPH1,FGFR1OP,ZNF496,SARNP,CNTROB,AP3S1,IL21R,NPLOC4,EIF2S2,SMC3,PSMA6,TNFAIP8,TIMM23,RAD23B,PPP6C,NAA50,CS,TIMELESS,TRA2B,FAM76B,PRADC1,TFG,IMPA2,FDFT1,RYBP,RPAP3,FYTTD1,LAP3,GOPC,PSMA1,FAM133B,RFC2,EIF4H,PDHX,SUPT16H,PPP2CA,NEK1,PPP2R5A,ELMO1,TONSL,SNAP23,MRPL27,SLC16A1,SLAIN1,VPS4A,NDE1,OAZ1,CDKN2A |
| 7.363e-05 | -9.52 | GSE3982_BCELL_VS_TH1_DN | MSigDB lists | GSE3982_BCELL_VS_TH1_DN | 184 | 48 | 17377 | 2626 |
TMEM106C,WSB2,ZNF207,NDUFS1,CLSPN,FOXM1,PTTG1,TAP1,RRM1,FLOT1,PXMP2,KIF2C,NCAPG,RAB11A,SPAG5,SLC31A1,RAD23B,GMEB1,PRC1,GTSE1,TAP2,RNF19A,NAP1L4,SAP30,PLK3,PPIF,TXNL1,PLK1,NASP,MKLN1,CDC123,RRM2,ITM2A,SLC25A22,MRPL16,NUP155,PDE3B,ASF1B,OPTN,GOLGA2,RBM47,TWSG1,NEIL3,FKBP5,KPNA2,WDR76,REEP4,PARD3 |
| 7.363e-05 | -9.52 | GSE15215_CD2_POS_VS_NEG_PDC_DN | MSigDB lists | GSE15215_CD2_POS_VS_NEG_PDC_DN | 184 | 48 | 17377 | 2626 |
UGP2,GORASP1,SF3B1,TMEM41B,MAGED1,TMEM109,UCK2,ENSA,DHX8,USP39,MAPK14,SDHA,TFRC,EBP,PSMA6,PTEN,DCP1A,TAF5L,PIKFYVE,STAT3,SRSF10,RHOA,ZFP64,ETV3,GABPA,CDC123,NCK1,JTB,EXOSC9,ODC1,GOLGA4,NEK1,PCM1,PPP2R5A,BRWD1,ACYP1,GADD45B,ERGIC3,NAGLU,DBI,RPLP1,DCAF11,RBMS1,IGBP1,CHPF2,RTN3,RNF139,ATMIN |
| 7.363e-05 | -9.52 | GSE22886_UNSTIM_VS_STIM_MEMORY_TCELL_UP | MSigDB lists | GSE22886_UNSTIM_VS_STIM_MEMORY_TCELL_UP | 184 | 48 | 17377 | 2626 |
IER2,LIME1,RPLP2,GGA1,DNAJB2,ANKH,CUTA,CERK,CREBL2,TOP2B,MXD4,DAZAP2,PIP4K2A,MOAP1,CAPN2,SHC1,PTEN,XPA,CDC25B,CNN2,CITED2,MYBL1,CNPY3,GPD1L,CTDSP2,EEF1D,ATP6V1G1,NAGPA,SEPT9,HMGN4,FBXO9,SSR2,PRMT2,NDRG3,RPS9,EIF3H,NMT2,MYO1F,NSA2,CAT,GOLGA7,OSBPL8,STK38,PPP6R3,PPP6R2,FAU,TMEM159,IGBP1 |
| 7.363e-05 | -9.52 | GSE27786_CD8_TCELL_VS_NEUTROPHIL_DN | MSigDB lists | GSE27786_CD8_TCELL_VS_NEUTROPHIL_DN | 184 | 48 | 17377 | 2626 |
SEPHS2,PRKAB1,TSC2,GORASP1,CDK2AP2,HEXB,ACAP1,CDCA8,CHKB,TMEM165,LYRM2,EPM2A,KIF5B,MDM2,MLX,CCNA2,TBC1D14,FOXN2,ABCD1,NFU1,FBXL19,NAA35,ASB6,HTRA2,PDLIM2,PHF10,TRAFD1,PPP1R18,SEPT9,AKT2,RAD51AP1,ZMYND11,PBK,PEF1,RBM38,ANKRD46,MASTL,TRAM2,CDC27,HIPK2,ARAP1,H2AFX,PKD2,HMGB2,SASS6,BRD9,ARHGAP23,CPEB2 |
| 7.363e-05 | -9.52 | GSE9037_CTRL_VS_LPS_1H_STIM_IRAK4_KO_BMDM_UP | MSigDB lists | GSE9037_CTRL_VS_LPS_1H_STIM_IRAK4_KO_BMDM_UP | 184 | 48 | 17377 | 2626 |
PPCS,CXXC1,RAE1,ADO,ENSA,NHLRC3,EZH1,ITGB5,MIEN1,RCOR3,CCDC28A,LIN9,RAB21,CENPJ,RCSD1,TTC9C,ATG13,MDFIC,ZNF710,TMBIM1,DRAM2,MED22,SP3,RBM42,ANKRD37,BAZ2A,GALC,CPOX,PFKFB3,DCTD,UTP3,SYVN1,HAGH,SCARB2,TMEM127,PDCD6,NSMCE2,STK38,DTX4,SSNA1,TRIM32,SMPD4,RUFY3,IDH3B,CDK2,HRAS,DYNC1LI2,LRCH1 |
| 7.363e-05 | -9.52 | GSE27786_NKTCELL_VS_MONO_MAC_UP | MSigDB lists | GSE27786_NKTCELL_VS_MONO_MAC_UP | 184 | 48 | 17377 | 2626 |
SYS1,DHPS,PRKCSH,BABAM1,PTTG1,TAP1,CDK13,SLC20A1,ZADH2,MYEF2,ATPAF1,WRNIP1,TMEM69,ZBTB45,PDCD10,THADA,HUWE1,INTS1,GPATCH1,SUCLG2,ATG13,APOOL,ZNRD1,NUP85,STRAP,PRPF19,TSHZ1,DDX24,LAP3,HARS,METTL5,BCLAF1,PRPSAP1,EIF3A,XRCC5,TIMM13,BRD2,STT3A,APPL2,BEND3,IDH3B,AKNA,YY1,NGLY1,SSSCA1,ZC3HAV1,GCSH,IPO4 |
| 7.363e-05 | -9.52 | GSE1460_NAIVE_CD4_TCELL_ADULT_BLOOD_VS_THYMIC_STROMAL_CELL_DN | MSigDB lists | GSE1460_NAIVE_CD4_TCELL_ADULT_BLOOD_VS_THYMIC_STROMAL_CELL_DN | 184 | 48 | 17377 | 2626 |
WSB2,HSPH1,GCLM,MAGEH1,HNRNPAB,DEPDC1,CYCS,PLXNA1,RGS2,OIP5,FANCL,CD59,SEC11A,AP3S2,IMPAD1,POP7,RAD23B,TPST1,SRI,TIMELESS,BCAP29,TAGLN2,APOOL,MOB1A,STRAP,PDLIM2,ERCC1,KLF10,POLR2L,CREG1,RAD51AP1,ATP2C1,CDC6,ICMT,MCM2,RAB1A,ARPC1A,DPYSL3,DNAJC10,OSBPL11,PDLIM1,HNRNPH3,CEP55,COX8A,ZDHHC7,CHEK2,SMAD4,HDAC2 |
| 7.371e-05 | -9.52 | GRUETZMANN_PANCREATIC_CANCER_UP | MSigDB lists | GRUETZMANN_PANCREATIC_CANCER_UP | 345 | 79 | 17377 | 2626 |
RHOG,ADAM10,TRIP10,GNPDA1,SLC2A1,TAP1,MYH9,DHX8,GLUD1,STMN1,PRNP,FLAD1,APLP2,CCNA2,SHC1,RALB,SRI,DNMT1,GM2A,GPX4,COPS8,BIRC3,HMGN4,MKI67,SLBP,DNAJA1,VDAC1,CBFB,RAB5B,DPYSL3,ACYP1,MAP4,STAT1,ADAM9,XRCC4,TUBB,GOLIM4,TM9SF4,SRGN,CENPF,DHX9,ITGB5,CSNK1A1,MYL6B,MFSD10,CFLAR,EXOSC7,PPIG,PPP1R8,TANK,ARL6IP1,ANXA5,ARHGEF2,CYTH1,PPP3CA,CYFIP1,RHOA,TNFAIP3,NSDHL,PRKDC,PARP4,LDHA,SEPT8,EMP3,PLEC,SNRPA,PSMB3,PRDX1,CBX3,AKAP1,ADSS,SERTAD2,CSK,YWHAZ,ASNA1,HMGB2,GPI,UBE2C,YWHAH |
| 7.372e-05 | -9.52 | GSE41978_KLRG1_HIGH_VS_LOW_EFFECTOR_CD8_TCELL_DN | MSigDB lists | GSE41978_KLRG1_HIGH_VS_LOW_EFFECTOR_CD8_TCELL_DN | 189 | 49 | 17377 | 2626 |
CYTIP,RPS2,SCAMP3,MRPS15,SRGN,TOR1AIP1,CTCF,CHCHD2,GLUD1,COX4I1,PCBP1,POLR3K,WDR48,RPL11,RAD23A,TERF2IP,APLP2,SUB1,PCNA,MSH2,FEM1B,RPL19,CENPM,APOOL,ABI1,PHF20L1,FTL,FAM49B,WDR1,RPS10,MRPL43,RPL6,RPL38,DNAJC9,EXOSC9,RPL27A,EIF4H,RPS9,EIF3A,ASF1B,RPL37,SEC31A,TRIM26,LTBP4,RPS14,RPLP1,ACTB,DDX5,RPS26 |
| 7.372e-05 | -9.52 | GSE17721_POLYIC_VS_CPG_1H_BMDC_UP | MSigDB lists | GSE17721_POLYIC_VS_CPG_1H_BMDC_UP | 189 | 49 | 17377 | 2626 |
MMACHC,MRPL9,SYS1,RPS6KA1,DYNLL1,PIGQ,RAC1,GADD45G,CSNK2A1,INO80E,HCFC1R1,CNOT3,PAPOLA,CSDE1,MED8,DUT,MTA1,PPP1R12C,PDCD2,GLTP,EIF5,ATF2,SENP1,SMC4,PREB,CDC5L,PPAN,ATP13A1,ERMP1,BRD4,PPP1R21,ZMYM5,SEPT8,BMS1,TOPORS,EIF4H,MATR3,GINS4,USP36,SOCS7,MYO1F,RBM25,TMEM54,MYO18A,RPLP1,TCOF1,TMEM101,FAU,TAF6 |
| 7.372e-05 | -9.52 | GSE41176_WT_VS_TAK1_KO_ANTI_IGM_STIM_BCELL_3H_DN | MSigDB lists | GSE41176_WT_VS_TAK1_KO_ANTI_IGM_STIM_BCELL_3H_DN | 189 | 49 | 17377 | 2626 |
WSB2,SRM,PPIB,EWSR1,NUP188,GNPDA1,URB2,EBNA1BP2,JMJD6,BCL2L1,FKBP2,BCAP31,HDDC2,RAD23A,EXOSC7,SEC24C,BANF1,RAD23B,AKR1B1,TARDBP,PDIA6,METTL1,NRAS,WDR18,ATP2C1,GBA,MRPL12,UTP3,TOMM40,DDX39A,MAK16,MAT2A,SRSF1,MAP3K4,KEAP1,STT3A,DUSP3,PSMD8,PSMD3,TIMM17A,MAPK6,MPV17,SRSF3,RGL1,CLN3,PLOD3,HEXA,BYSL,FUBP1 |
| 7.372e-05 | -9.52 | GSE46606_DAY1_VS_DAY3_CD40L_IL2_IL5_STIMULATED_IRF4_KO_BCELL_DN | MSigDB lists | GSE46606_DAY1_VS_DAY3_CD40L_IL2_IL5_STIMULATED_IRF4_KO_BCELL_DN | 189 | 49 | 17377 | 2626 |
TCF12,PRPF38B,DEPDC1,WDYHV1,XIAP,LAGE3,TIA1,UCK1,PXMP2,SUPT7L,RPAIN,XPR1,MXD1,KIAA1147,SAC3D1,TNFAIP8,PRC1,INTS12,RNF19A,NIPSNAP1,USP34,NIPAL3,TNFAIP3,KLF10,NQO2,KAT7,PGS1,GALK2,PBRM1,STK17B,ANKRD46,KRIT1,PON2,GOLGA4,OSBPL11,JAK1,L3MBTL3,PTER,LUC7L3,GADD45B,CEP55,CAPN7,MAP4,SLAIN1,CHEK2,VPS4A,WDR91,CCNB2,VPS29 |
| 7.372e-05 | -9.52 | GSE28726_ACT_CD4_TCELL_VS_ACT_VA24NEG_NKTCELL_DN | MSigDB lists | GSE28726_ACT_CD4_TCELL_VS_ACT_VA24NEG_NKTCELL_DN | 189 | 49 | 17377 | 2626 |
PNISR,HLA-E,SRSF6,SRGN,ASAH1,DNAJB1,DAZAP2,RGS2,RGS1,MOAP1,ZNF428,CAPN2,DLG5,ADD3,AKAP8,ATG13,CDC25B,PIK3IP1,MOB1A,EIF5,VPS13B,USP34,SP3,CYTH1,TNFAIP3,BTG2,KAT7,CIRBP,RPL38,MCL1,NFATC2IP,SOX4,TAZ,EIF4G2,RBM38,EIF3A,TRAM2,BRWD1,RPL32,GPS2,CHD3,AXIN1,CCDC69,YWHAZ,DDX5,PPP6R2,H3F3A,CLN3,TOB1 |
| 7.372e-05 | -9.52 | GSE339_CD8POS_VS_CD4CD8DN_DC_IN_CULTURE_DN | MSigDB lists | GSE339_CD8POS_VS_CD4CD8DN_DC_IN_CULTURE_DN | 189 | 49 | 17377 | 2626 |
RMND5A,HSPH1,NOP2,RPS6KA1,TRIM11,TCF3,ANKH,HNRNPUL2,CIB1,RPL15,EIF1B,APP,SLC31A1,PRKD3,DPYSL2,ARHGEF1,TNPO3,OSTF1,ZRANB1,CNOT6L,OGG1,S100A6,NUDC,FDFT1,CDC5L,DDX24,ERF,LRRC8A,KRAS,DNAJA1,SMC2,PBRM1,CBFB,TTC33,USP21,FKBP3,MAT2A,SMAP2,XRCC5,RDH11,EPRS,KPNA1,OGT,ZRANB2,RBBP4,LTA4H,TAF6,UBE2C,NMD3 |
| 7.372e-05 | -9.52 | GSE411_WT_VS_SOCS3_KO_MACROPHAGE_DN | MSigDB lists | GSE411_WT_VS_SOCS3_KO_MACROPHAGE_DN | 189 | 49 | 17377 | 2626 |
NCOR2,MAX,ST13,GMFG,CAST,MECP2,VAV2,TOR1AIP1,TRMT6,STRN4,C5orf30,SMC6,TOP2B,ARGLU1,DAZAP2,C19orf48,ZADH2,METTL3,TRIM65,GOLM1,NUP210,INTS7,SIAH1,DPYSL2,TRMU,MCMBP,DVL2,HNRNPM,EID1,WIPF1,MIER2,NFATC2IP,ARID1A,AMDHD2,FANCE,USP21,FKBP3,XRCC5,VEZF1,PCM1,SMAD2,ZNF689,ZC3H7B,FAM126A,NCOA1,MAP3K5,ZMIZ1,SMURF1,GPATCH4 |
| 7.372e-05 | -9.52 | GSE19198_CTRL_VS_IL21_TREATED_TCELL_24H_DN | MSigDB lists | GSE19198_CTRL_VS_IL21_TREATED_TCELL_24H_DN | 189 | 49 | 17377 | 2626 |
TRIM41,RPS6KA1,DAP,ANKH,HEXB,CDC42SE2,MXD4,RGS2,PRKACA,CRLF3,PIP4K2A,DDRGK1,SNRNP25,RPN1,MSH2,ANP32A,CDC25B,CORO1A,FAM76B,TPCN1,MSH6,ALDH9A1,SMC4,PDPK1,TGFB1,SGCE,ZMYND11,LRBA,LDB1,LACTB,PACS1,MEF2D,MCFD2,VKORC1,MAPK3,HAUS8,DERL1,DUSP3,NRM,GALNT10,GPI,NDUFS5,LTA4H,ABCA1,CPEB2,MYL12B,RAB3IL1,HIGD2A,S100PBP |
| 7.372e-05 | -9.52 | GSE26488_CTRL_VS_PEPTIDE_INJECTION_HDAC7_DELTAP_TG_OT2_THYMOCYTE_DN | MSigDB lists | GSE26488_CTRL_VS_PEPTIDE_INJECTION_HDAC7_DELTAP_TG_OT2_THYMOCYTE_DN | 189 | 49 | 17377 | 2626 |
TMEM106C,UBE2D3,RWDD1,EIF3D,MAGED1,ANK3,LAGE3,FLOT1,PAWR,MAN2B1,DNAJB1,OAT,CPNE3,MAN1A1,SHC1,IMPAD1,PIK3R2,ZNF746,ANP32A,H2AFY,TTC3,TIPARP,CARM1,B3GALT6,PTPN18,GABPA,BTG2,POLR2D,RNPS1,ARID1A,ESYT1,ZFAND5,MBD3,SLC50A1,UTP20,TRIM47,HSPBP1,GALNT2,PDLIM1,MAFK,CDCA5,STAT1,GLG1,ZFP90,ZNF598,PURA,GCSH,IPO4,ZC3HC1 |
| 7.372e-05 | -9.52 | GSE32128_INOS_DEPENDENT_VS_INOS_INDEPENDENT_ACTIVATED_TCELL_UP | MSigDB lists | GSE32128_INOS_DEPENDENT_VS_INOS_INDEPENDENT_ACTIVATED_TCELL_UP | 189 | 49 | 17377 | 2626 |
CYTIP,MIF4GD,DNMT3A,COPA,PRKCSH,FAM53C,MCCC1,UBE2Z,ARFIP2,TBC1D13,PPP3CB,DNAJB1,PRKACA,BCAT2,HDAC7,PPP4R1,ZNF326,SOCS6,AKR1B1,ANXA5,RNF19A,TIPARP,LRRC59,TPCN1,DVL2,CGGBP1,TGFB1,RPRD1A,MAPRE2,ZMYND11,WBP2,KCTD20,RCOR1,ARID1A,BUD13,RAB1A,HSPA1B,PI4K2A,DERL1,HLA-B,GOLGA4,CCDC6,GPS2,MAPK6,SEL1L,RBMS1,CAB39,DUSP11,TRAF5 |
| 7.372e-05 | -9.52 | GSE5960_TH1_VS_ANERGIC_TH1_DN | MSigDB lists | GSE5960_TH1_VS_ANERGIC_TH1_DN | 189 | 49 | 17377 | 2626 |
GNPDA1,SLC41A1,PIGQ,MECP2,TMEM109,DLGAP4,SLC29A1,AP3S1,PRKACA,LCLAT1,REEP5,REPS1,FBXO3,ATP6V0B,MDM2,NEK6,SLC44A1,FAM89B,ANXA5,TNPO2,RPN2,RNF19A,AHCYL1,TMBIM1,ABCC1,SRPK2,PDPK1,CYFIP1,POLR2G,NEK7,UBE2V1,BRCA1,CYB5A,ECH1,AMZ2,PCM1,TXNDC16,RBL1,STAT6,CORO1C,YWHAH,CD81,LONP2,TOB1,CAPN1,TUBB,CSNK1D,FUBP1,PTOV1 |
| 7.377e-05 | -9.51 | HMG14_17 | pfam domains | PF01101 | 5 | 5 | 17054 | 2545 |
HMGN3,HMGN1,HMGN5,HMGN4,HMGN2 |
| 7.386e-05 | -9.51 | cytoskeletal part | cellular component | GO:0044430 | 1616 | 293 | 18223 | 2701 |
FGFR1OP,PDCD6IP,ADD1,TAP1,CNTROB,CCNB1,KIFC1,CALM2,CDK5,ANKRD26,NEK6,DNM2,CDC25B,SPATC1L,KCNAB2,PLK3,NSUN2,KIF15,TOPORS,AURKB,DIDO1,CCNF,SLC25A5,EIF3A,KRIT1,WAS,MID1IP1,RAD18,KIF18B,MAP4,MYO18A,KLHL42,SLF1,TRAF5,AAAS,ANXA11,HSPH1,MAPRE1,DHX9,RAB23,KIF23,HAUS4,PSEN1,HAUS2,MYL6B,LMNA,SPAG5,RTKN,TMEM250,CEP104,SMC3,ARPC5,FBXL7,GNAI2,NUP85,WDR1,SEPT8,MAP7D1,CAPZA2,MAP2K2,CCT8,FNTA,GOLGA2,FAM83D,NDE1,CFAP20,CDK2,ALS2,ZNF207,NDC1,POC1A,ACTR3,RAC1,OLA1,TPX2,MYH9,NIT2,BCL2L1,PRKACA,STMN1,APP,CLUAP1,MTA1,SEPT11,RNF19A,CEP63,RPRD1B,CFL1,DCTN1,CCT2,PSRC1,MAPRE2,NARF,CUL3,NUSAP1,SHCBP1,SERP1,EML4,CENPU,PPP2CA,KIF2A,CDC16,DSN1,PPP2R5A,CCDC14,H2AFX,TRIM32,GEN1,LRP8,CSNK1D,TUBB,DYNC1LI2,PKP4,MZT1,MECP2,FLOT1,WDR5,SPDL1,IFT27,RAB11A,MAD2L2,NEIL2,JAKMIP1,CAPN2,CLIC4,CENPJ,PRC1,AXIN2,GTSE1,CNN2,IFT46,SPTAN1,NUDC,STAU1,KAT2A,TCTEX1D2,TACC1,NEK7,JTB,PARP4,MACF1,KIF11,MARK2,SPPL2B,MYO1F,CBX3,KIF18A,KEAP1,TTLL4,LRPPRC,CCDC69,SSNA1,WDR62,ESPL1,NPHP4,SKA3,KMT2E,WDR13,SIRT2,KIF2C,MAPK14,MAP1LC3B,DST,DLG5,ZNF804A,RAB8A,PCNA,SYNM,CDC42,DPYSL2,RCSD1,XRCC2,KIF22,RP2,MTPN,CARMIL1,TACC3,PLK1,RPP25,SEPT9,PBXIP1,FOPNL,CKAP2L,EZR,CDC6,BRCA1,ANLN,DPYSL3,SEPT1,HSPB11,CHD3,VPS4A,ROCK1,DVL1,SASS6,C2CD5,MYL12B,CEP170B,TMUB1,PPP1R12A,CENPF,CIB1,KLC1,RACGAP1,NCKAP1,RAPGEF6,DTL,RB1,CCP110,KIF13B,CAPZA1,KIFAP3,KNTC1,MCPH1,ATP6V0D1,CAMSAP1,PSMA1,SEPT7,ARPC1A,DAPK3,MASTL,HAUS8,TSC1,PCM1,CDC27,ODF2,NLRC5,SLC16A1,NUP62,RUVBL2,MYO9A,CCNB2,ECPAS,MZT2B,BCCIP,CYLD,FAM92A,DYNLL1,SLC2A1,TWF2,RAD23A,ABRAXAS2,KIF14,CORO1A,DNAL4,POC5,PRPF19,TUBGCP5,WIPF1,BICD2,TMEM201,TULP3,CEP55,GAS2,AKNA,MAPK1,REEP4,SMAD4,RAD51D,KIF3B,CTDP1,KLHL21,RAE1,CDK2AP2,DCTN2,SCYL1,CDCA8,PAWR,MYO9B,CSNK1A1,TUBGCP2,SAC3D1,FBXO5,FERMT3,KIF5B,STARD9,MZT2A,SLC1A4,ARHGEF2,MYO5A,MICAL3,ASPM,RANGAP1,HSPA1B,NEK1,ATP6V1D,BIRC5,FAM110A,SNAP29,E2F1,USP20,PKD2,TERF1 |
| 7.392e-05 | -9.51 | GCGSCMNTTT_UNKNOWN | MSigDB lists | GCGSCMNTTT_UNKNOWN | 67 | 23 | 17377 | 2626 |
PSPC1,KAT7,PPP1R15B,RAC1,ZBED5,BCLAF1,RAB1A,SRSF1,SUPT16H,SUV39H2,TMED10,RBMX,LUC7L3,SAFB,PITX1,PDS5B,FBXL7,TARDBP,PCYT2,CHTOP,USP11,ARID4A,SMC4 |
| 7.392e-05 | -9.51 | GO_POSITIVE_REGULATION_OF_CELL_CYCLE_PHASE_TRANSITION | MSigDB lists | GO_POSITIVE_REGULATION_OF_CELL_CYCLE_PHASE_TRANSITION | 67 | 23 | 17377 | 2626 |
TGFB1,PLK1,UBE2E2,BRD4,GORASP1,PHB2,CUL3,CDC6,RAB1A,RAB11A,APP,FBXO5,RB1,RAD51C,MDM2,GOLGA2,PTEN,BIRC5,NSMCE2,CDCA5,FAM83D,UBE2C,ESPL1 |
| 7.404e-05 | -9.51 | RHO GTPases Activate WASPs and WAVEs | REACTOME pathways | R-HSA-5663213 | 36 | 16 | 10287 | 1696 |
WASF2,CYFIP1,WAS,CDC42,NCK1,ARPC5,ACTR3,RAC1,WIPF1,ACTB,NCKAP1,CYFIP2,ARPC1A,MAPK1,ABI1,MAPK3 |
| 7.404e-05 | -9.51 | N-glycan trimming in the ER and Calnexin/Calreticulin cycle | REACTOME pathways | R-HSA-532668 | 36 | 16 | 10287 | 1696 |
MLEC,PRKCSH,MAN1B1,UBXN1,MOGS,SYVN1,EDEM2,RNF103,DERL1,RPS27A,RAD23B,SEL1L,NGLY1,RNF139,PSMC1,RNF5 |
| 7.410e-05 | -9.51 | TTF2 (transcription termination factor 2) | protein interactions | 8458 | 59 | 22 | 17029 | 2761 |
PDCD6IP,DRAP1,MYBL2,TOP3A,CNTROB,MATR3,RAB2B,PSMC4,TFAP4,HNRNPA2B1,PCM1,NVL,HDAC7,DCP1A,CBWD1,ACAT1,CREB1,SMAD1,PPP6R1,TACC3,DCTN1,CDC5L |
| 7.410e-05 | -9.51 | THOC7 (THO complex 7) | protein interactions | 80145 | 59 | 22 | 17029 | 2761 |
FYTTD1,SARNP,THOC1,PPP1R2,RBM8A,MRPL12,DHX9,ALKBH5,BCLAF1,DDX39A,RPA1,DDX17,RPA2,MED8,EIF4A3,GOT2,CCDC14,CHD3,UBE3C,CHTOP,MED22,USP13 |
| 7.424e-05 | -9.51 | MYH10 (myosin heavy chain 10) | protein interactions | 4628 | 71 | 25 | 17029 | 2761 |
PRKAB1,ILF3,MYH9,CUL1,BRCA1,CAPZA2,ESYT1,SEPT7,RAB11A,BCAP31,FKBP3,RPA1,RPA2,SHC1,CDC42,EIF4A3,PTEN,PIK3R2,FUS,CDK2,GNAI2,ARRB2,ECPAS,HNRNPM,TERF2 |
| 7.448e-05 | -9.50 | GO_PROTEIN_LOCALIZATION_TO_ENDOPLASMIC_RETICULUM | MSigDB lists | GO_PROTEIN_LOCALIZATION_TO_ENDOPLASMIC_RETICULUM | 121 | 35 | 17377 | 2626 |
SRP72,RPS15,RPL29,RPS2,RPL35,RPLP2,SEC61G,RPS10,RPL6,RPL38,RPL8,RPL15,RPS24,RPL27A,RPS9,BCAP31,RPSA,RPL11,RPL36,RPL23A,RPL37,CHMP4A,SEC61A1,RPL32,RPS27A,RPL17,RPS14,RPLP1,ANKRD13C,RPL19,CHMP4B,BCAP29,FAU,RPS26,KDELR1 |
| 7.459e-05 | -9.50 | actomyosin contractile ring organization | biological process | GO:0044837 | 7 | 6 | 17256 | 2622 |
KIF23,RACGAP1,PDCD6IP,VPS4A,ANLN,RTKN |
| 7.492e-05 | -9.50 | HMGN_fam | interpro domains | IPR000079 | 5 | 5 | 18492 | 2768 |
HMGN3,HMGN1,HMGN5,HMGN4,HMGN2 |
| 7.511e-05 | -9.50 | Helicase_C | interpro domains | IPR001650 | 108 | 32 | 18492 | 2768 |
DDX58,RECQL,DDX47,SHPRH,YTHDC2,CHD1L,DHX9,SMARCA4,DHX8,BLM,CHD1,DDX56,EIF4A3,DDX31,DDX28,SNRNP200,DDX24,DHX29,BTAF1,DDX20,DDX39A,DHX57,DHX15,DDX17,DDX23,RAD54B,DHX16,CHD3,DDX5,DDX42,POLQ,DDX52 |
| 7.512e-05 | -9.50 | NDUFA13 (NADH:ubiquinone oxidoreductase subunit A13) | protein interactions | 51079 | 67 | 24 | 17029 | 2761 |
NDUFA5,NDUFV2,EXOSC6,NDUFS1,NDUFB6,TIMMDC1,TMEM126B,NDUFA4,KRAS,MTMR12,NDUFA7,BLM,ATP5PF,NDUFS7,NDUFS4,NDUFV1,ATP6V1D,HUWE1,L3MBTL3,TIMM23,NDUFS8,NDUFS5,STAT3,NDUFA3 |
| 7.512e-05 | -9.50 | MAP4 (microtubule associated protein 4) | protein interactions | 4134 | 67 | 24 | 17029 | 2761 |
MTA2,HNRNPF,LSM8,WDHD1,BRCA1,ERBIN,CCNB1,KIF11,USP21,ISG15,POLR2A,RPA1,RXRB,RPA2,PDCD6,IARS,HNRNPR,PPP4R1,CRY2,TARDBP,POT1,TERF1,TUBB,SRPK2 |
| 7.513e-05 | -9.50 | MRTO4 (MRT4 homolog, ribosome maturation factor) | protein interactions | 51154 | 63 | 23 | 17029 | 2761 |
NIFK,NOP2,RRP15,DDX24,CUL3,GTPBP4,EBNA1BP2,BRIX1,RPL23A,CAND1,KRR1,TERF2IP,NSA2,DDX56,EIF2S2,ZNF746,EFTUD2,PML,NOC2L,FBL,NMD3,FTSJ3,IFI16 |
| 7.513e-05 | -9.50 | OXCT1 (3-oxoacid CoA-transferase 1) | protein interactions | 5019 | 63 | 23 | 17029 | 2761 |
PTMS,SUCLG1,WDR1,RAE1,TOR1AIP1,PSEN1,MAPK14,SDHA,CBX3,ADSS,C12orf10,SGSH,NDUFV1,AHNAK,HINT1,ATIC,PTPN11,SEPT11,MDH1,TCOF1,TALDO1,TMEM9,MTPN |
| 7.513e-05 | -9.50 | PFKM (phosphofructokinase, muscle) | protein interactions | 5213 | 63 | 23 | 17029 | 2761 |
DYNLL1,SUMO2,CUL3,PSMG1,ARFIP2,BRCA1,CAPZA2,PKM,MCFD2,PCBP1,COMMD4,KIF11,PICALM,MAPK3,PTPRF,HGS,PCNA,SIAH1,ZNF746,DCP1A,MAPK1,PFKP,CDC5L |
| 7.519e-05 | -9.50 | Ppp6c (protein phosphatase 6, catalytic subunit) | protein interactions | 67857 | 33 | 15 | 17029 | 2761 |
ANKRD28,NOP9,DST,PGAP2,CCT2,DDOST,PRKDC,USP42,DLGAP4,ARHGEF2,PPP6R2,PPP6R3,IGBP1,PPP6R1,CCT8 |
| 7.519e-05 | -9.50 | NDUFB4 (NADH:ubiquinone oxidoreductase subunit B4) | protein interactions | 4710 | 33 | 15 | 17029 | 2761 |
NDUFV2,NDUFV1,TOMM20,TIMMDC1,RAB7A,TCF3,NDUFA11,PPP4R1,LAMTOR3,MPV17,NDUFA4,ABCD1,NDUFS5,VDAC1,NDUFS4 |
| 7.519e-05 | -9.50 | ZNF346 (zinc finger protein 346) | protein interactions | 23567 | 33 | 15 | 17029 | 2761 |
PPP2CA,NOA1,ZNF512,ILF3,OLA1,TARDBP,EBNA1BP2,SNRPG,PRKRA,BRIX1,ANKHD1,CCDC59,KRR1,HP1BP3,CAND1 |
| 7.553e-05 | -9.49 | protein transporter activity | molecular function | GO:0008565 | 92 | 29 | 17224 | 2647 |
PGAP2,USO1,SEC61B,TOMM20,NXT1,SEC61G,MCL1,NUTF2,TOMM40,RUFY1,KPNA4,EIF4ENIF1,TIMM13,RAP1A,KPNA1,VPS26C,VPS26B,TIMM23,TIMM17A,RAB4A,MIA2,TNPO3,TNPO2,KPNA2,CHMP7,AP2S1,IPO4,VPS29,NXT2 |
| 7.576e-05 | -9.49 | RHO GTPase Effectors | REACTOME pathways | R-HSA-195258 | 294 | 74 | 10287 | 1696 |
WASF2,RHOG,H2AFZ,ACTR3,RAC1,MYH9,NUF2,KIF2C,KTN1,MIS12,CALM2,AHCTF1,CDC42,KIF14,NUP107,CDKN1B,ABI1,DVL2,SEH1L,PLK1,NCK1,GOPC,TAOK1,WIPF1,AURKB,H2AFV,CENPU,KIF2A,PPP2CA,WAS,PPP2R5A,DSN1,LIMK1,ITGB1,H2AFX,ACTB,ROCK1,DVL1,H3F3A,MAPK1,MYL12B,MAPRE1,PPP1R12A,RHOC,CENPF,CDCA8,KLC1,NCKAP1,PMF1,SPDL1,RTKN,KIF5B,ARPC5,PRC1,KNTC1,CENPM,NUP85,NCOA2,NUDC,PDPK1,CYFIP1,RHOA,RANGAP1,CYFIP2,MEN1,ARPC1A,RHOB,MAPK3,KIF18A,BIRC5,YWHAZ,CENPT,NDE1,YWHAH |
| 7.605e-05 | -9.48 | ZF_RING_2 | prosite domains | PS50089 | 284 | 63 | 12060 | 1670 |
MIB2,TRIM41,TRAF7,SHPRH,PHRF1,TRIM11,XIAP,BRAP,CBLL1,ZNRF3,RUFY1,TRIM65,BIRC2,ANKIB1,RNF103,RFWD3,CYHR1,RNF121,MDM2,MEX3C,SIAH1,ZNRF2,RNFT1,LTN1,TTC3,RNF19A,RNF135,RNF26,LRSAM1,RNF5,RNF169,RLIM,TRIM8,LONRF3,BIRC3,RBX1,RNF25,PCGF6,RFFL,LNX2,TOPORS,SYVN1,BRCA1,KMT2C,PCGF1,TRIM28,TRIM4,TRIM47,TRIM26,COMMD3-BMI1,RAD18,DTX4,SIAH2,PML,RNF38,UHRF2,TRIM32,TRIM52,RNF14,TRAF5,ZNF598,RNF139,RNF114 |
| 7.646e-05 | -9.48 | GO_SMALL_GTPASE_MEDIATED_SIGNAL_TRANSDUCTION | MSigDB lists | GO_SMALL_GTPASE_MEDIATED_SIGNAL_TRANSDUCTION | 340 | 78 | 17377 | 2626 |
WASF2,RHOG,RAB14,RAB11B,NF1,RAC1,RRAGC,MAPK14,PARK7,CRKL,VAV1,RAB21,RAB8A,RAP1A,CCNA2,SHC1,CDC42,SAR1A,RALB,RAB35,RAB4A,DNMT1,ARL5A,CFL1,SHOC2,RHOBTB3,NRAS,RAB7A,RAB1A,RAB5B,ARL5B,RAB22A,TRIM28,RAB2B,ARF4,RHEB,KRIT1,RAB24,LIMK1,ROCK1,RHEBL1,SH2D3A,RHOC,VAV2,RAB23,BRAP,ARFIP2,NCKAP1,ARF1,RAB6A,MYO9B,DOCK11,IFT27,RAB11A,RAPGEF6,RTKN,RB1,ARF5,ARHGEF1,CYFIP1,RHOA,MAPKAPK3,RFXANK,RABIF,KRAS,RIT1,RHOT1,RHOT2,RHOB,RAB18,GNA12,ELMO1,SIAH2,RGL1,CDK2,HRAS,CDKN2A,ALS2 |
| 7.662e-05 | -9.48 | WANG_LMO4_TARGETS_DN | MSigDB lists | WANG_LMO4_TARGETS_DN | 324 | 75 | 17377 | 2626 |
MBD1,EXOC3,RAB14,FEZ2,GGNBP2,MRPS15,NDUFAF2,EIF3D,XIAP,MEAF6,CDC42,SAR1A,RNASEK,TARDBP,BCAP29,RBM15,PTPRK,WDR41,CLPTM1,SRP72,LARS,MKLN1,AATF,EHMT1,PCGF6,DDX20,TOPORS,GSTCD,KRTCAP2,AP4E1,EIF3A,CCDC127,OPTN,CHMP4A,FBXO28,DGCR8,RNASEL,ATP6V0E1,DYNC1LI2,CCDC137,ZNF445,TRIP12,PDAP1,LYRM2,FBXO3,MED10,RNFT1,CWC27,FUT8,TTC17,NSUN4,RB1CC1,ABCF2,ACSL3,CAPZA2,FXR1,ZNF407,PHF6,ZFR,SMAP2,SH3GLB1,RDH11,RAB18,RBM25,DUSP3,BBX,TYW5,MAPK6,EXOC4,PSAP,ATP6V1C1,NAA20,CPEB2,NRBP1,GPATCH4 |
| 7.670e-05 | -9.48 | CFTR (cystic fibrosis transmembrane conductance regulator) | protein interactions | 1080 | 196 | 53 | 17029 | 2761 |
PPIB,HSPH1,DNAJC5,TRIP12,PRKAA1,DNAJB1,XPNPEP3,UBE2I,PRKACA,RAB11A,REPS1,BCAP31,DTL,CD59,KIF5B,FARSA,PSMD2,ATP2A2,AHSA1,SEPT11,TNPO3,MARCH2,PTGES3,TFG,GNAI2,CFL1,RNF5,CLCN3,SEPT9,SIGMAR1,ERLIN1,PRKDC,GOPC,EZR,USP10,DNAJA1,ESYT1,ERBIN,RHOT1,PSMB3,PSMC4,CAND1,DERL1,PPP2CA,PDCD6,HSPA4,SEC61A1,JAK1,SNAP23,ATXN2L,SARAF,PSAP,VPS4A |
| 7.709e-05 | -9.47 | apoptotic signaling pathway | biological process | GO:0097190 | 296 | 70 | 17256 | 2622 |
DDX47,IFI27L1,NF1,RAF1,TMEM109,CUL1,BCL2L1,MOAP1,PDK2,SIVA1,FNIP2,TP53BP2,SENP1,HTRA2,TIMM50,PGAP2,BAK1,CUL3,MCL1,TOPORS,BRCA1,DIDO1,DNAJC10,DAP3,HINT1,HIPK2,FASTK,STK11,TICAM1,CHEK2,CLU,E2F2,ZMAT3,EYA2,ANXA6,DAP,SRGN,CDIP1,CIB1,CYCS,PAWR,FOXO3,JMY,APOPT1,FGFR3,PDCD10,XPA,DAPK1,MSH2,BCL2,MSH6,PDPK1,TGFB1,PRKDC,ERO1A,UBE4B,RHOT1,RHOT2,APPL1,FADD,DAPK3,FAS,PDCD6,PML,E2F1,AEN,DDX5,MAP3K5,HRAS,IFI16 |
| 7.715e-05 | -9.47 | TSR1 (TSR1, ribosome maturation factor) | protein interactions | 55720 | 118 | 36 | 17029 | 2761 |
RPS2,MRPL39,MRPS26,LAMTOR3,EIF1B,PARN,MRPL19,PNO1,RPA2,MRPL50,LYAR,SUB1,TARDBP,NUP153,MRPL40,POLR1B,FTSJ3,MRPL32,DCTN1,RPS10,RPS24,OGDH,GAR1,RPS9,RPSA,CAND1,RPA1,MRPL2,RPS14,KBTBD7,FAU,ECPAS,RPS26,IFI16,BYSL,SMNDC1 |
| 7.745e-05 | -9.47 | GO_PROTEIN_LOCALIZATION_TO_MEMBRANE | MSigDB lists | GO_PROTEIN_LOCALIZATION_TO_MEMBRANE | 367 | 83 | 17377 | 2626 |
SYS1,AGRN,RPLP2,RAB11B,RAC1,ANK3,RPL11,SSR1,RPL23A,MOAP1,CDK5,RAB8A,ATG3,ZFYVE27,SRP72,RPL29,RPL35,AKT2,RPL38,EZR,NUP155,ICMT,RPS9,RPSA,OPTN,RPL37,TRAM2,HSPA4,PEX5,CHMP4A,SEC61A1,RPS27A,TULP3,RPS14,RPLP1,CHMP4B,ROCK1,DVL1,FAU,SMURF1,TSPAN5,RPS26,PARD3,RPS15,RPS2,FLOT1,NKD2,NUP54,RPL15,RAB11A,WRB,RAPGEF6,ATG4A,RPL17,PPIL2,ARL6IP1,RPL19,PACS2,MYO5A,TMED2,GCC2,DENND4C,RPL8,RPL6,RPS10,RPS24,SSR2,PACS1,RAB3IP,RPL27A,MACF1,SH3GLB1,RPL36,HGS,FNTA,GOLGA4,RPL32,GOLGA7,NSF,OSBPL8,ASNA1,SSNA1,FAM126A |
| 7.767e-05 | -9.46 | KIN (Kin17 DNA and RNA binding protein) | protein interactions | 22944 | 9 | 7 | 17029 | 2761 |
RPA2,PCNA,METTL22,PABPC1,EIF2D,RPA1,DNAJC17 |
| 7.767e-05 | -9.46 | EIF1 (eukaryotic translation initiation factor 1) | protein interactions | 10209 | 9 | 7 | 17029 | 2761 |
UPF2,EIF5,EIF3G,APP,EIF2D,MAPK6,DHX9 |
| 7.773e-05 | -9.46 | ZBTB48 (zinc finger and BTB domain containing 48) | protein interactions | 3104 | 92 | 30 | 17029 | 2761 |
TRIM41,RPS15,DDX24,MRPS2,TEX10,PTTG1,CDK2AP2,GTPBP4,MRPS10,CTCF,BMS1,PBRM1,CDC23,RGS2,MAK16,ZNF121,DHX57,NSA2,DAP3,ZNF777,RPL32,DGCR8,RBM34,FBXO7,RPF2,UPF2,FTSJ3,ZC3HAV1,DVL2,ZBTB24 |
| 7.795e-05 | -9.46 | Spliceosome, 35S U5-snRNP | KEGG pathways | hsa_M00355 | 37 | 16 | 7161 | 1149 |
CDC40,SNRNP200,XAB2,SNRPB,PPIE,CRNKL1,SNRPD3,HSPA1B,EFTUD2,BUD31,GPATCH1,AQR,SNRPG,ISY1-RAB43,CDC5L,PRPF19 |
| 7.795e-05 | -9.46 | Spliceosome, 35S U5-snRNP | KEGG pathways | M00355 | 37 | 16 | 7161 | 1149 |
CDC40,SNRNP200,XAB2,SNRPB,PPIE,CRNKL1,SNRPD3,HSPA1B,EFTUD2,BUD31,GPATCH1,AQR,SNRPG,ISY1-RAB43,CDC5L,PRPF19 |
| 7.816e-05 | -9.46 | granulocyte activation | biological process | GO:0036230 | 496 | 107 | 17256 | 2622 |
RHOG,ADA2,KARS,RAB14,KMT2E,ADAM10,DYNLL1,RAC1,HEXB,NIT2,NHLRC3,GYG1,MAPK14,KCMF1,CMTM6,CPNE3,PA2G4,RAP1A,PSMD1,AP1M1,BRI3,TMBIM1,GM2A,KCNAB2,ENPP4,CPNE1,CCT2,TIMP2,NRAS,RAB7A,ARHGAP45,PPIE,CYSTM1,PSMB7,ATP6V0A1,RAB5B,TOLLIP,ALDH3B1,DSN1,AGPAT2,DDOST,SURF4,RAB24,PSMD3,CAB39,CANT1,ATP6V0C,ROCK1,PDXK,LTA4H,MAPK1,CAPN1,TUBB,SVIP,MIF,DNAJC5,GMFG,MANBA,PDAP1,LAMTOR3,B4GALT1,ASAH1,CDK13,MAN2B1,RAB6A,PSEN1,TMEM179B,GNS,CD59,PSMD2,CTSS,ARPC5,HUWE1,OSTF1,CNN2,MVP,LPCAT1,SPTAN1,CYFIP1,FTL,MLEC,RHOA,CREG1,C1orf35,HEBP2,PKM,ARMC8,CCT8,NEU1,HSPA1B,PI4K2A,CAND1,XRCC5,CAT,RAB18,ATP6V1D,MAGT1,GOLGA7,SNAP29,SNAP23,ACLY,PGRMC1,IMPDH1,CTSA,PSAP,GPI,PGAM1 |
| 7.825e-05 | -9.46 | RHOA (ras homolog family member A) | protein interactions | 387 | 182 | 50 | 17029 | 2761 |
COX15,PPP1R12A,RHOC,VAV2,TRIO,SLC25A12,PRKACA,BIRC2,KTN1,RTKN,VAV1,MDM2,KLHL20,PTEN,NVL,SH3BP1,DPYSL2,HDAC7,ARHGEF1,CDKN1B,ARHGEF2,RPN2,DVL2,RHOA,NET1,CUL3,EZR,KRAS,ARHGDIB,ARHGEF12,GORASP2,NUTF2,ICMT,ANLN,SLC25A5,GOSR1,MARK2,CLNS1A,FADD,FAS,PON2,SMAD2,RPS27A,SH3GLB2,MPV17,NAXE,CTSA,ROCK1,SMURF1,DEF6 |
| 7.826e-05 | -9.46 | MCM7 (minichromosome maintenance complex component 7) | protein interactions | 4176 | 168 | 47 | 17029 | 2761 |
CYLD,MCM10,SF3B1,SUZ12,DCTN2,RBM8A,DBF4,ORC1,HAUS2,APP,GSTK1,RB1,PSMD2,PCNA,NEK6,KMT5C,MCM5,AHSA1,PELO,TIMELESS,CDKN1B,CRY2,ORC3,MCMBP,TERF2,GINS1,PLK1,STAU1,MAPRE2,VHL,CUL3,CDC6,MCM2,ASF1B,POLR2A,GINS4,RPA1,MBIP,GOLGA2,RBL1,TONSL,DDX5,RBBP4,CDK2,TERF1,VPS29,SSRP1 |
| 7.881e-05 | -9.45 | GO_PROTEIN_IMPORT | MSigDB lists | GO_PROTEIN_IMPORT | 150 | 41 | 17377 | 2626 |
POLA2,TOMM20,NUP188,TSC2,PHB2,RAE1,NUP54,RPAIN,NUP205,LMNA,SNUPN,TIMM23,NUP107,TNPO2,TNPO3,F2R,STAT3,NUP85,TIMM50,TGFB1,PPP3CA,SEC61B,NUP155,NUTF2,TOMM40,PTTG1IP,MAPK3,KPNA4,PEX5,KPNA1,HSPA4,TIMM17A,ARNTL,PML,NUP62,KPNA2,CLU,MAPK1,LONP2,TOB1,IPO4 |
| 7.881e-05 | -9.45 | GSE15624_CTRL_VS_3H_HALOFUGINONE_TREATED_CD4_TCELL_DN | MSigDB lists | GSE15624_CTRL_VS_3H_HALOFUGINONE_TREATED_CD4_TCELL_DN | 150 | 41 | 17377 | 2626 |
POLA2,DNMT3A,ANXA6,NDUFAF2,MRPL39,SUZ12,DYNLL1,SLC2A1,TM9SF3,ARFIP2,RGS1,CALM2,DTL,ANKLE1,CCDC50,MCM5,PPME1,MECR,ANXA5,CENPM,RNF26,MED22,CSTF1,EIF3L,TCTEX1D2,TSTA3,RNASEH2C,VHL,TMEM147,KIF11,RPL36,PRIM1,SDHB,RAB18,DAP3,TBL3,E2F4,E2F1,PDXK,SLC25A39,TMEM131 |
| 7.932e-05 | -9.44 | GO_NUCLEAR_CHROMATIN | MSigDB lists | GO_NUCLEAR_CHROMATIN | 282 | 67 | 17377 | 2626 |
MBD1,TCF12,DNMT3A,H2AFZ,MPHOSPH8,SUZ12,CSNK2A1,SMARCA4,SIRT2,INO80E,MXD1,SAP130,UCHL5,TARDBP,SMARCE1,GABPA,WBP2,H2AFV,MBD3,TRIM28,ASF1B,CHAF1A,BRMS1,SMAD2,E2F4,STAT6,H2AFX,STAT1,UHRF2,ACTB,ANP32E,NCOA1,BEND3,H3F3A,SMAD4,HDAC2,NCOR2,MECP2,TCF3,MEF2A,IRF4,MBD2,BUD31,H2AFY,TIMELESS,CITED2,CREB1,STAT3,MSH6,KAT2A,ETV3,NASP,MTA2,LDB1,POLR3GL,ARID1A,MEN1,CBX3,RBMX,SETD3,CDCA5,E2F1,HMGB2,RUVBL2,YY1,RBBP4,IPO4 |
| 7.947e-05 | -9.44 | PSMB5 (proteasome subunit beta 5) | protein interactions | 5693 | 105 | 33 | 17029 | 2761 |
USP7,HSPH1,CYLD,CAST,TAP1,CUL1,POMP,RAD23A,KIF5B,PSMD2,PSMD1,PSMA6,UCHL5,FBXO7,YBX1,TAP2,PLK1,PSMA8,PSMB7,PSMA1,KRAS,BRCA1,MCM2,PSMB9,PSMB3,PSMC4,PSMD3,PSMD8,ASNA1,UBE2C,TERF1,PSMC1,GCSH |
| 7.947e-05 | -9.44 | PSMA4 (proteasome subunit alpha 4) | protein interactions | 5685 | 105 | 33 | 17029 | 2761 |
PPIB,COX15,CYLD,EWSR1,BABAM1,CUL1,CSNK2A1,POMP,RAD23A,HNRNPA2B1,HERC3,KIF5B,PSMD2,PSMD1,PSMA6,HUWE1,UCHL5,YBX1,PLK1,PSMA8,PSMB7,PSMA1,PSMB9,PSMB3,PSMC4,WDR11,GOLGA2,PSMD3,E2F4,PSMD8,ASNA1,SMURF1,PSMC1 |
| 7.958e-05 | -9.44 | C19orf70 (chromosome 19 open reading frame 70) | protein interactions | 125988 | 17 | 10 | 17029 | 2761 |
CHCHD3,IMMT,LAMTOR3,CYCS,MTX1,APOOL,CLN3,MTX2,CHCHD6,STOML2 |
| 7.958e-05 | -9.44 | TFDP2 (transcription factor Dp-2) | protein interactions | 7029 | 17 | 10 | 17029 | 2761 |
LIN9,RB1,RBL1,E2F4,PCGF6,E2F1,E2F3,E2F2,COMMD8,RYBP |
| 8.004e-05 | -9.43 | Cdca8 (cell division cycle associated 8) | protein interactions | 52276 | 20 | 11 | 17029 | 2761 |
CLPTM1,NAP1L1,POLR2L,CLSPN,FOXM1,CDCA3,RRM1,CDCA8,EBNA1BP2,AURKB,CCDC71L |
| 8.004e-05 | -9.43 | TIGD6 (tigger transposable element derived 6) | protein interactions | 81789 | 20 | 11 | 17029 | 2761 |
MAGED2,SNX27,MTA1,ACSL3,NUP54,ZRANB2,TAGLN2,HDGFL2,MRPL13,ABCF1,CHAF1A |
| 8.007e-05 | -9.43 | tRNA transport | biological process | GO:0051031 | 35 | 15 | 17256 | 2622 |
NDC1,TOMM20,NUP188,NUP210,RAE1,NUP107,NUP54,NUP62,NUP153,NUP155,NUP85,NUP58,AAAS,SEH1L,NUP205 |
| 8.038e-05 | -9.43 | V$NMYC_01 | MSigDB lists | V$NMYC_01 | 256 | 62 | 17377 | 2626 |
ZNF296,DNMT3A,NDUFS1,MAX,ANXA6,ADAM10,ZFP91,SCYL1,UBXN1,GADD45G,MXD4,DCUN1D4,SLC20A1,SYNRG,FOXO3,PABPC4,DNAJB9,WWP2,ATP6V0B,PDK2,PA2G4,SLC38A5,UTP18,YBX1,BCL2,NUP153,RBM3,ALDH18A1,FBL,STAT3,PABPC1,SOCS5,USP34,AMPD2,SRP72,NRAS,KLF10,MAPKAPK3,LAP3,WBP2,SCFD2,PFKFB3,ESYT1,KRTCAP2,KDM3A,EPB41,RXRB,HMGN2,ADSS,TMED10,CCDC6,GADD45B,LPCAT4,BCL7C,AEN,FKBP5,ABCA1,GCSH,SLC25A33,B4GALT2,IPO4,ATXN7L2 |
| 8.054e-05 | -9.43 | GSE6090_UNSTIM_VS_DC-SIGN_STIM_DC_UP | MSigDB lists | GSE6090_UNSTIM_VS_DC-SIGN_STIM_DC_UP | 155 | 42 | 17377 | 2626 |
GOLIM4,SUZ12,TPX2,RACGAP1,LACTB2,CHAC2,SDHA,ELMOD2,RHBDD1,JMY,SRXN1,DTL,KIF5B,UCHL5,FIZ1,PTPN11,MECR,RNASEH2A,ALDH18A1,TMED2,TDP1,PPP3CA,GABPA,TMEM126B,SCFD2,BMS1,WBP1,FOXRED1,RFC2,TWISTNB,RDH11,XRCC5,EIF4ENIF1,KPNA1,SMAD2,NSF,TULP3,STAT6,SPCS3,BEND6,GEN1,TSEN15 |
| 8.075e-05 | -9.42 | regulation of gene silencing | biological process | GO:0060968 | 135 | 38 | 17256 | 2622 |
NCOR2,NDC1,NUP188,POLR2K,RAE1,AGO2,DHX9,NUP54,NUP205,NUP210,NUP107,H2AFY,NUP153,STAT3,DNMT1,NUP85,SEH1L,TGFB1,PPP3CA,POLR2I,POLR2L,POLR2G,MIER1,POLR2D,NUP155,FXR1,TRIM28,MAP2K2,POLR2A,ATAD2,POLR2J,UHRF2,NUP62,DDX5,H3F3A,CDK2,NUP58,AAAS |
| 8.110e-05 | -9.42 | JOHNSTONE_PARVB_TARGETS_3_UP | MSigDB lists | JOHNSTONE_PARVB_TARGETS_3_UP | 400 | 89 | 17377 | 2626 |
AGRN,MYH9,SEC16A,SLC25A37,PRNP,APLP2,NT5DC1,MTA1,RNASEK,BRI3,DVL2,PCBP2,ACSL5,TRIM8,TIMP2,KLF10,SEPT9,PBXIP1,RAB7A,LYRM1,HTATIP2,SLC17A5,DIDO1,TANC1,STX16,PSMB9,SLC50A1,OPTN,ALDH3B1,AHNAK,ATP1A1,DDOST,JAK1,RBM47,STAT6,PRDX5,MAP4,NAGLU,ATP6V0C,ACTB,CLU,SMURF1,SLC25A39,ABCA1,CAPN1,PDCD4,KIF3B,PARP12,KIAA0100,HLA-E,B4GALT5,TRIO,VAV2,TKT,ASAH1,ABHD14B,NOTCH2,ASXL2,GNS,GSTK1,ADD3,CTSS,HUWE1,FUT8,MDFIC,MVP,CITED2,PHF10,MLEC,CREG1,PPP1R21,SYVN1,KLF6,RHOB,ECH1,SH3BP5,CAT,HLA-B,PLD3,FNTA,GOLGA2,ACLY,NLRC5,CCDC69,MEGF9,CTSA,PSAP,NR2F2,TOB1 |
| 8.152e-05 | -9.41 | GO_ANAPHASE_PROMOTING_COMPLEX_DEPENDENT_CATABOLIC_PROCESS | MSigDB lists | GO_ANAPHASE_PROMOTING_COMPLEX_DEPENDENT_CATABOLIC_PROCESS | 76 | 25 | 17377 | 2626 |
PLK1,PSMA8,PTTG1,PSMB7,PSMA1,ANAPC2,AURKB,CDC23,CCNB1,PSMD9,PSMB9,PSMB3,PSMC4,PSMD2,PSMA6,CDC16,PSMD1,CDC27,RPS27A,PSMD8,PSMD3,ANAPC7,UBE2C,PSMC1,ANAPC4 |
| 8.152e-05 | -9.41 | MORF_SP3 | MSigDB lists | MORF_SP3 | 76 | 25 | 17377 | 2626 |
SP3,SNRNP200,RAC1,SUMO2,GMFB,STARD7,RAB6A,PRPSAP1,EIF4H,SERP1,RPA1,HNRNPA2B1,DAP3,ARPC5,UTP18,PARG,RAD23B,COX7A2L,MDH1,COIL,MYL12B,TMED2,ZNF146,SMNDC1,EBAG9 |
| 8.158e-05 | -9.41 | NFIA (nuclear factor I A) | protein interactions | 4774 | 44 | 18 | 17029 | 2761 |
NOP2,DHX9,RPS24,TFAP4,SMAD2,SURF4,RBM25,LUC7L3,ZNF326,TRA2B,SRSF3,RBPJ,CREB1,RRS1,FTSJ3,SMAD4,HP1BP3,SRSF10 |
| 8.158e-05 | -9.41 | PWP1 (PWP1 homolog, endonuclein) | protein interactions | 11137 | 44 | 18 | 17029 | 2761 |
DDX24,ANK3,CUL3,GTPBP4,RPL15,CUL1,BLM,APP,CAND1,UTP20,RBM34,DDA1,COPS6,FBL,SMURF1,FTSJ3,DDB1,IFI16 |
| 8.176e-05 | -9.41 | anaphase-promoting complex-dependent catabolic process | biological process | GO:0031145 | 80 | 26 | 17256 | 2622 |
PLK1,PSMA8,PTTG1,PSMB7,CUL3,PSMA1,ANAPC2,AURKB,CCNB1,CDC23,PSMD9,PSMB9,PSMB3,PSMC4,PSMD2,PSMA6,PSMD1,CDC16,CDC27,RPS27A,PSMD8,PSMD3,ANAPC7,UBE2C,PSMC1,ANAPC4 |
| 8.197e-05 | -9.41 | SGCGSSAAA_V$E2F1DP2_01 | MSigDB lists | SGCGSSAAA_V$E2F1DP2_01 | 160 | 43 | 17377 | 2626 |
H2AFZ,CLSPN,ZCCHC8,RMI2,SMC6,ASXL2,FBXO5,TFAP4,PCNA,SMC3,MSH2,TRA2B,MRPL40,MCMBP,DNMT1,NASP,PRKDC,ILF3,E2F3,DNAJC9,RRM2,CDC6,NFATC2IP,PKMYT1,MCM2,H2AFV,POLR2A,SRSF1,CAND1,ATAD2,SYNCRIP,HNRNPR,DCK,ZNF367,LUC7L3,KBTBD7,E2F1,AP1S1,NUP62,FKBP5,WDR62,GEN1,PRPF4B |
| 8.209e-05 | -9.41 | THOC1 (THO complex 1) | protein interactions | 9984 | 88 | 29 | 17029 | 2761 |
BCCIP,FYTTD1,PWWP2A,SARNP,THOC1,ZCCHC8,SF3B1,MRPL12,DHX9,DHX8,KRAS,BCLAF1,THRAP3,FXR1,DDX39A,RPA1,ATG4A,SF3B2,MOAP1,RPA2,RB1,EIF4A3,GTSE1,DUSP11,CHTOP,ZNF830,ZC3H3,RBM15B,USP13 |
| 8.224e-05 | -9.41 | V$NFY_Q6_01 | MSigDB lists | V$NFY_Q6_01 | 251 | 61 | 17377 | 2626 |
HIVEP3,COMMD10,ZBTB10,GGNBP2,UGP2,ZFP91,TRMT6,SLC2A1,AGPAT1,RACGAP1,HMGN3,DCUN1D4,PRKACA,IFT27,STMN1,LCLAT1,BCAT2,RPA2,MRPL50,PDK2,GART,ATP2A2,MTMR4,TTC9C,RBM3,FAM76B,MOB1A,GNAI2,SPSB3,RNF5,ZNF189,FDFT1,PLK1,RHOA,MLEC,SIGMAR1,HELB,ABCF2,TOMM40,BORA,KDM3A,ARL17A,USP21,SNRPA,HSPA1B,HMGN2,C19orf54,KPNA4,SMAD2,PPP2R5A,HNRNPR,ELMO1,ZNF436,SEL1L,ATXN2L,MLYCD,LY75,DHTKD1,NDE1,RBBP4,LRP8 |
| 8.226e-05 | -9.41 | negative regulation of cell cycle G2/M phase transition | biological process | GO:1902750 | 107 | 32 | 17256 | 2622 |
GPR132,CLSPN,BABAM1,CUL1,BLM,PSMD9,FANCI,DTL,PSMD2,PSMA6,PSMD1,BABAM2,H2AFY,FBXL7,PLK1,PSMA8,RBX1,TAOK1,PSMB7,PSMA1,MRNIP,BRCA1,AURKB,PSMB9,PSMB3,PSMC4,RPS27A,PSMD3,PSMD8,VPS4A,ZNF830,PSMC1 |
| 8.232e-05 | -9.40 | BIOCARTA_P38MAPK_PATHWAY | MSigDB lists | BIOCARTA_P38MAPK_PATHWAY | 39 | 16 | 17377 | 2626 |
TGFB1,HMGN1,MAX,RAC1,MEF2A,MEF2D,ELK1,MAPK14,MKNK1,CDC42,SHC1,STAT1,MAP3K5,CREB1,ATF2,HRAS |
| 8.232e-05 | -9.40 | GNF2_NS | MSigDB lists | GNF2_NS | 39 | 16 | 17377 | 2626 |
HMGN1,PRKDC,OLA1,GTPBP4,ADSL,GLO1,CCT8,HNRNPA2B1,EPRS,MTHFD2,IARS,ATIC,MRPS27,LRPPRC,MRPL3,MSH6 |
| 8.242e-05 | -9.40 | extracellular vesicle | cellular component | GO:1903561 | 2140 | 377 | 18223 | 2701 |
RAB14,TXN,PDCD6IP,H2AFZ,LUZP1,ADAM10,HEXB,TMEM109,NANS,PLXNA1,PARK7,RPL23A,NAPG,PA2G4,RAB4A,AP1M1,DNM2,SLC26A2,MOB1A,MGAT5,PCBP2,RHOBTB3,NRAS,GNG7,PPFIA3,SMC2,NUTF2,GALNT7,RAB22A,RAB2B,ARF4,AHNAK,WAS,RPS27A,RPS14,PTER,PRDX5,ITGB1,ATP6V0C,PFKP,ANXA11,SVIP,PPIB,HSPH1,HLA-E,RHOC,CUTA,B4GALT1,MAN2B1,ITGB5,VPS25,MYL6B,GNS,CD59,ARPC5,SNX18,MEGF8,ATIC,GEMIN4,MVP,GNAI2,PABPC1,PPA1,CYFIP1,FTL,CPQ,PRRC2A,WDR1,MAN1B1,PIP4K2C,ITM2A,EXOSC9,PLEC,CAPZA2,PKM,PTTG1IP,CYFIP2,CCT8,RHOB,PSMB3,FAS,CAT,ADSS,PTPRF,SCARB2,TXNDC16,CSK,RBMX,ACLY,APPL2,MDH1,GPI,CFAP20,HEXA,RHOG,RAB11B,TRIP10,RAC1,ACTR3,OLA1,MYH9,NIT2,PRKACA,SAFB2,STMN1,CPNE3,APP,GNB2,RAB21,APLP2,AHCTF1,RALB,DUT,TALDO1,GPD1L,TMBIM1,CFL1,ATP6V1G1,GPX4,CPNE1,ENPP4,CCT2,TAOK1,CUL3,ATP6V0A1,DNAJA1,GSTCD,RAB1A,PSMB9,H2AFV,PPP2CA,CHCHD3,ALDH3B1,HSPA4,HINT1,H2AFX,PDXK,B4GALT3,TUBB,GALK1,RPS2,SCAMP3,ANXA6,FLOT1,TKT,ABHD14B,ATP5F1B,SPR,PMVK,RAB11A,TUT4,WWP2,MAT2B,CAPN2,PSMD2,PDCD10,CLIC4,ITGB8,HUWE1,AHSA1,ARF5,FUT8,NAA50,ANXA5,TAGLN2,S100A6,HNRNPM,LYPLA2,SPTAN1,LDHB,STAU1,TNFAIP3,STRIP1,PARP4,LDHA,HEBP2,ECH1,PRDX1,PLD3,NUCB1,SGSH,HGS,WNT5B,DBI,CAPN7,FAM3C,NAXE,LY75,ASNA1,DDX5,PSAP,CD81,YWHAH,DDB1,UBL3,ST13,COPA,AGRN,GNPDA1,FAM129A,MOGS,SND1,TAF6L,PRNP,RAB8A,PCNA,RAP1A,CDC42,GOT2,RAB35,IL6ST,ZNHIT6,DPYSL2,SLC44A1,SRI,AKR1B1,RP2,CARMIL1,CDC37,COPS8,LAP3,MBLAC2,CYSTM1,EZR,ARHGDIB,UBE2V1,RAB5B,RHEB,UEVLD,NAGLU,CAB39,ADAM9,ARRDC1,ACTB,STK11,CLU,VPS4A,RPS26,MYL12B,CAPN1,UBE2D3,UFC1,LAMTOR3,CIB1,ASAH1,RACGAP1,DNAJB1,NCKAP1,THRAP3,RAB6A,EPHX2,SUB1,VASP,CAPZA1,YBX1,AHCY,TMEM8A,SLC12A2,HDHD2,ATP6V0D1,ABCC1,ALDH9A1,TSTA3,CREG1,NQO2,GBA,PSMA1,SEPT7,ARPC1A,APPL1,CAND1,GNAS,GOLGA4,SNAP23,SLC16A1,YWHAZ,DNPH1,CTSA,PITPNA,RUVBL2,ATP5F1A,EHD4,N4BP2L2,WASF2,CHMP2A,UGP2,RPLP2,MDH2,SLC2A1,ATP6V1B2,LYN,PCBP1,TWF2,EXT2,RPL11,HNRNPA2B1,NRF1,PSMA6,IARS,CS,PDCD2,CORO1A,CYB5R1,MINPP1,AHCYL1,LMAN1,PDIA6,ABI1,GM2A,CHP1,PSMA8,PPT1,RAB7A,BTG2,GLO1,VDAC1,CHMP2B,TOLLIP,PEF1,RPS9,RPSA,EIF3H,GLOD4,ATP1A1,PSMD3,CANT1,CHMP4B,FKBP5,SCARB1,H3F3A,SMURF1,LTA4H,CHID1,MIF,KIF3B,TOR3A,DCTN2,AGO2,ARF1,SLC12A9,DNAJB9,TFRC,MAN1A1,SPPL2A,FERMT3,GSTK1,GART,SLC1A4,H2AFY,FBL,MYO5A,SLC25A1,RHOA,ACP2,FAM49B,CSRP1,TUFM,ARHGEF12,NDRG3,NEU1,TARS,DDX23,HSPA1B,CTSL,ATP6V1D,PDCD6,ATAD2,GOLGA7,PLAA,GLG1,ACAT1,PKD2,ATP6V1C1,PLOD3,ARHGAP23,PGAM1,SAT2 |
| 8.272e-05 | -9.40 | GO_SMALL_NUCLEAR_RIBONUCLEOPROTEIN_COMPLEX | MSigDB lists | GO_SMALL_NUCLEAR_RIBONUCLEOPROTEIN_COMPLEX | 59 | 21 | 17377 | 2626 |
SART1,SNRNP200,SF3B1,SNRPB,PRPF3,SNRPD3,PRPF39,TXNL4A,LUC7L,SF3A2,SNRPA,PRPF18,SF3B2,DDX23,LSM6,LUC7L3,PRPF4,SNRPG,GEMIN4,SNRNP70,LUC7L2 |
| 8.272e-05 | -9.40 | GO_POSITIVE_REGULATION_OF_NUCLEAR_DIVISION | MSigDB lists | GO_POSITIVE_REGULATION_OF_NUCLEAR_DIVISION | 59 | 21 | 17377 | 2626 |
TGFB1,PLK1,GORASP1,PHB2,CUL3,LRP5,NUSAP1,SIRT2,RAB1A,BECN1,FBXO5,RB1,GOLGA2,PTEN,BIRC5,NSMCE2,CDCA5,H2AFY,UBE2C,TERF1,ESPL1 |
| 8.295e-05 | -9.40 | BIOCARTA_ETS_PATHWAY | MSigDB lists | BIOCARTA_ETS_PATHWAY | 18 | 10 | 17377 | 2626 |
NCOR2,ETV3,ETS2,RBL1,E2F4,E2F1,DDX20,ETS1,HRAS,HDAC2 |
| 8.305e-05 | -9.40 | BIOCARTA_ERK_PATHWAY | MSigDB lists | BIOCARTA_ERK_PATHWAY | 28 | 13 | 17377 | 2626 |
PPP2CA,GNAS,MKNK1,SHC1,RPS6KA1,RAF1,ITGB1,ELK1,MAPK1,STAT3,MAP2K2,HRAS,MAPK3 |
| 8.344e-05 | -9.39 | HALLMARK_PEROXISOME | MSigDB lists | HALLMARK_PEROXISOME | 103 | 31 | 17377 | 2626 |
ACSL5,ELOVL5,ERCC1,ATXN1,CADM1,SLC35B2,EPHX2,ECH1,PRDX1,RDH11,NUDT19,CAT,GSTK1,IDE,PEX5,SIAH1,CRAT,ACOX1,PRDX5,MSH2,MLYCD,SLC25A19,ABCD1,MVP,YWHAH,CLN6,PABPC1,HRAS,LONP2,ALDH9A1,ABCC5 |
| 8.363e-05 | -9.39 | SNRPN (small nuclear ribonucleoprotein polypeptide N) | protein interactions | 6638 | 114 | 35 | 17029 | 2761 |
CDC40,CYLD,XAB2,SF3B1,SUZ12,SNRPD3,PDCD7,SF3B2,SNUPN,CMTR2,EFTUD2,BUD31,GPATCH1,AQR,FBL,CSTF1,SNRNP200,RBM42,CRNKL1,LSM8,KRAS,PRPF3,TXNL4A,SF3A2,SNRPA,CLNS1A,DDX23,GEMIN5,UPF1,KEAP1,LSM6,PRPF4,SNRPG,SNRNP70,COIL |
| 8.363e-05 | -9.39 | PSMD7 (proteasome 26S subunit, non-ATPase 7) | protein interactions | 5713 | 114 | 35 | 17029 | 2761 |
COX5B,ATXN3,EWSR1,TRIM11,PSMD9,KCMF1,KTN1,UBLCP1,SRXN1,RAD23A,PSMD2,NDUFV1,PSMD1,PSMA6,HUWE1,UCHL5,DCTN1,TXNL1,PSMA8,PSMB7,PSMA1,SYVN1,BRCA1,RAB1A,MCFD2,TOMM40,PSMB9,ABCF1,PSMB3,PSMC4,SYNCRIP,PSMD3,PSMD8,USP20,PSMC1 |
| 8.418e-05 | -9.38 | XIAP (X-linked inhibitor of apoptosis) | protein interactions | 331 | 150 | 43 | 17029 | 2761 |
UBE2D3,UBE2E2,CASP6,PHB2,DYNLL1,WDYHV1,RAF1,MAGED1,RAC1,PTTG1,XIAP,GMCL1,IRF3,BLM,UBE2I,BIRC2,USP5,MDM2,NEK6,PTEN,SIAH1,SIVA1,AHCY,HTRA2,CCT2,USO1,TRIM8,BIRC3,RNPS1,UBE2V1,BRCA1,TOLLIP,ERC1,C19orf54,SEC23IP,HSPA4,CDCA4,BIRC5,TAB2,PRDX3,E2F1,TRIM32,USP11 |
| 8.420e-05 | -9.38 | Golgi cisterna membrane | cellular component | GO:0032580 | 91 | 28 | 18223 | 2701 |
MOB4,NAGPA,B3GALT6,GOLIM4,TMEM115,GOLPH3L,APH1A,B4GALT5,GPR89A,B4GALT1,TMED3,B4GALT4,BCAP31,NUCB1,RAB21,ASAP2,GALNT2,GOLGA2,GOLGA8A,FUT8,ARAP1,CANT1,ST3GAL2,B4GALT3,CHPF2,TMED2,B4GALT2,GPR89B |
| 8.458e-05 | -9.38 | GSE37301_CD4_TCELL_VS_RAG2_KO_NK_CELL_DN | MSigDB lists | GSE37301_CD4_TCELL_VS_RAG2_KO_NK_CELL_DN | 175 | 46 | 17377 | 2626 |
OTUD5,GLT8D1,CASP6,VAV2,ABCB10,PLXNA1,SEC16A,SYNRG,REEP5,ARID1B,LMNA,EEF2K,CAPN2,SNUPN,SLC44A1,ATP13A3,RRBP1,TTC17,CLTB,GM2A,RNF169,TACC1,NQO2,EHMT1,EZR,ATP6V0A1,RCOR1,NLN,PACS1,PLEC,HERPUD2,BUD13,EML4,SH3GLB1,PI4K2A,CACNB1,PDCD6,MID1IP1,ITPRIPL1,TATDN2,ACLY,ST3GAL2,NCOA1,ARHGAP23,ATP6V0E1,CPEB2 |
| 8.458e-05 | -9.38 | GSE17721_POLYIC_VS_PAM3CSK4_16H_BMDC_DN | MSigDB lists | GSE17721_POLYIC_VS_PAM3CSK4_16H_BMDC_DN | 175 | 46 | 17377 | 2626 |
PPIB,NDUFV2,RPS2,DAP,MEF2A,AGPAT3,NOTCH2,MAPK14,TMEM165,GLRX3,CD320,C12orf10,MRPL50,ATP6V0B,SNRNP25,ERH,AHCTF1,EIF4A3,PPP6C,TRA2B,NDUFS8,RNF19A,MRPL48,LRRC59,NUP85,HDHD2,EEF1D,TIMM8B,NSDHL,RPL38,WBP2,ARHGEF12,DCUN1D5,RPS9,ADSS,ALG3,TMEM184C,SEC31A,ATP1A1,WAS,SERF2,RAD18,ACOX1,ACADM,COPS6,DDB1 |
| 8.472e-05 | -9.38 | GO_NUCLEOTIDYLTRANSFERASE_ACTIVITY | MSigDB lists | GO_NUCLEOTIDYLTRANSFERASE_ACTIVITY | 117 | 34 | 17377 | 2626 |
POLA2,CTU2,CMAS,CDS2,UGP2,POLR2K,NANS,POLR3K,PAPOLA,FLAD1,CD3EAP,RPAP1,PCYT2,POLR1B,PTGES3,ZNRD1,TERF2,POLR2I,PRIM2,POLR2L,POLR2G,POLK,POLR2D,POLR3GL,POLG2,POLR2A,TWISTNB,PRIM1,POLR2J,UAP1,POLE,CRCP,TERF1,POLQ |
| 8.476e-05 | -9.38 | purine NTP-dependent helicase activity | molecular function | GO:0070035 | 97 | 30 | 17224 | 2647 |
DDX28,RECQL,DDX47,SNRNP200,DDX24,DHX29,HELB,CHD1L,YTHDC2,DHX9,DHX8,DDX20,BLM,DDX39A,CHD1,DHX15,DHX57,XRCC5,DDX17,DDX23,DDX56,UPF1,EIF4A3,DHX16,CHD3,DDX31,DDX5,RUVBL2,DDX42,DDX52 |
| 8.476e-05 | -9.38 | ATP-dependent helicase activity | molecular function | GO:0008026 | 97 | 30 | 17224 | 2647 |
DDX28,RECQL,DDX47,SNRNP200,DDX24,DHX29,HELB,CHD1L,YTHDC2,DHX9,DHX8,DDX20,BLM,DDX39A,CHD1,DHX15,DHX57,XRCC5,DDX17,DDX23,DDX56,UPF1,EIF4A3,DHX16,CHD3,DDX31,DDX5,RUVBL2,DDX42,DDX52 |
| 8.494e-05 | -9.37 | GSE36392_EOSINOPHIL_VS_MAC_IL25_TREATED_LUNG_DN | MSigDB lists | GSE36392_EOSINOPHIL_VS_MAC_IL25_TREATED_LUNG_DN | 180 | 47 | 17377 | 2626 |
GALK1,WDYHV1,XIAP,DLGAP4,THRAP3,SLC35B1,MAPK14,PARK7,RRP36,APOPT1,NPLOC4,FBXO3,SEC11A,GSTK1,PDXP,TBC1D22A,AP3S2,PPIL2,SOCS6,GPATCH1,PRADC1,LRRC59,TACC3,TERF2,NAGPA,MLEC,NET1,GTPBP4,NFATC2,SMC2,EDEM2,BORA,GUF1,NDRG3,RAB22A,SH3GLB1,GLOD4,NECAP2,PRIM1,DTWD1,MRPL2,POLR2J,ARNTL,DNAJC17,CHID1,GPATCH4,RHEBL1 |
| 8.494e-05 | -9.37 | GSE3982_MAC_VS_CENT_MEMORY_CD4_TCELL_UP | MSigDB lists | GSE3982_MAC_VS_CENT_MEMORY_CD4_TCELL_UP | 180 | 47 | 17377 | 2626 |
NDUFV2,ENSA,NENF,ORC1,GLRX3,LYN,CHKA,EBP,MBD4,RPN1,APLP2,CTSS,MRPL40,AHCYL1,MYO5A,SAP30,TIMM8B,CYFIP1,ERCC1,TK1,AGGF1,ACP2,GALC,PPT1,NSDHL,AMD1,ACSL3,RRM2,AZI2,VDAC1,SOX4,KIF11,PICALM,ZDHHC3,RHBDF2,TMEM184C,PLD3,GNA12,KEAP1,MTHFD2,PRDX3,TIMM17A,SEL1L,COX8A,GPI,PDXK,TUBB |
| 8.494e-05 | -9.37 | GSE14908_ATOPIC_VS_NONATOPIC_PATIENT_RESTING_CD4_TCELL_DN | MSigDB lists | GSE14908_ATOPIC_VS_NONATOPIC_PATIENT_RESTING_CD4_TCELL_DN | 180 | 47 | 17377 | 2626 |
HIVEP3,CCNC,HSPH1,SARNP,CHD1L,PTP4A3,GLRX3,CPNE3,MFSD10,CD320,SAC3D1,NDUFS4,PRNP,KIFC1,CDKN2C,RNFT1,BDH1,FEM1B,KIFAP3,CYB5R1,FBL,RNF26,ALDH9A1,NASP,AATF,TMEM39A,NSUN2,TMEM216,BMS1,SEPT7,EIF3A,PSMC4,GLOD4,MASTL,SURF4,STT3A,EIF2D,NDUFA11,WDR4,ACLY,H2AFX,COX8A,CRCP,ATF6,SNRPG,IDH3B,TMEM33 |
| 8.499e-05 | -9.37 | GSE2128_CTRL_VS_MIMETOPE_NEGATIVE_SELECTION_DP_THYMOCYTE_C57BL6_DN | MSigDB lists | GSE2128_CTRL_VS_MIMETOPE_NEGATIVE_SELECTION_DP_THYMOCYTE_C57BL6_DN | 190 | 49 | 17377 | 2626 |
ABCA3,GGA1,WDYHV1,CHD1L,AGPAT3,PAWR,GGPS1,CPNE3,MIS12,CAPN2,HERC3,CLUAP1,NEK6,GOT2,UCHL5,SSBP3,TTC9C,SLC44A1,GLTP,CYB5R1,ZNF710,SCYL3,N4BP2,ARID4A,ABCC1,PPAN,PTPN18,SNRNP200,SIGMAR1,PPT1,LRBA,MAP4K4,PACS1,PRKRA,TANC1,PSMB9,TSR2,CHCHD6,ERC1,PI4K2A,MAP3K4,BRMS1,HLA-B,TTLL4,MBOAT1,GPI,WDR76,AKNA,E2F2 |
| 8.499e-05 | -9.37 | GSE22140_HEALTHY_VS_ARTHRITIC_GERMFREE_MOUSE_CD4_TCELL_UP | MSigDB lists | GSE22140_HEALTHY_VS_ARTHRITIC_GERMFREE_MOUSE_CD4_TCELL_UP | 190 | 49 | 17377 | 2626 |
SART1,IER2,MRPL9,SCAMP3,DHPS,PHB2,KLHL21,LAGE3,KCTD17,BTN3A1,TWF2,MAPK14,GGPS1,FARSA,NFATC3,SH3BP1,TBC1D22A,GOT2,NDUFS8,CYC1,PLCL2,ARID4A,GPX4,VOPP1,ZDHHC18,PTPN18,PRIM2,HMGN4,DCAF8,RTF1,USP22,CBFA2T2,PSMB9,SNRPA,CYB5A,RDH11,MYO1F,EPRS,CSK,STAT6,STAT1,ARAP1,OGT,DCAF11,LY75,LTA4H,PGAM1,NUDT3,USP13 |
| 8.499e-05 | -9.37 | GSE15930_NAIVE_VS_72H_IN_VITRO_STIM_IL12_CD8_TCELL_UP | MSigDB lists | GSE15930_NAIVE_VS_72H_IN_VITRO_STIM_IL12_CD8_TCELL_UP | 190 | 49 | 17377 | 2626 |
RECQL,NQO1,KIAA0100,KLHL21,RAE1,STRN4,UCK1,PCSK7,AP1B1,SPR,C19orf48,GGPS1,APP,MBD4,SUB1,ZKSCAN1,SIAH1,ZNF326,CLTB,POU2AF1,METTL1,TRAFD1,TMEM115,TIMP2,DDX24,KAT2A,CREG1,IDH3A,SUGP2,TOR1AIP2,MAP4K3,ADRB2,WBP1,AZI2,ICAM2,SOX4,SPPL2B,USP21,SF3A2,BSDC1,PI4K2A,CANT1,PITPNA,DVL1,PSAP,SPRYD4,PPP6R3,BRWD3,SMARCD1 |
| 8.499e-05 | -9.37 | GSE34515_CD16_POS_MONOCYTE_VS_DC_UP | MSigDB lists | GSE34515_CD16_POS_MONOCYTE_VS_DC_UP | 190 | 49 | 17377 | 2626 |
CCNC,HIVEP3,ARID5A,CHIC2,AGFG1,EIF2AK4,TMEM165,TMEM161B,RNF103,LMNA,XPR1,CSDE1,ABL2,TNFAIP8,SAR1A,PPIG,UBA5,LPIN2,TRA2B,TAF5L,TP53BP2,PABPC1,MGAT5,ZNF800,MYO5A,FYTTD1,RPAP3,MOB4,DDX28,STAU1,TCTEX1D2,ZMYND11,PPIE,MIER1,NUP155,KLF6,STK17B,SERP1,RPA1,DDX17,VEZF1,PON2,CCDC6,FAM110A,ZC3H7B,SLC25A19,ZMIZ1,BRD9,ANXA11 |
| 8.499e-05 | -9.37 | GSE339_EX_VIVO_VS_IN_CULTURE_CD4POS_DC_UP | MSigDB lists | GSE339_EX_VIVO_VS_IN_CULTURE_CD4POS_DC_UP | 190 | 49 | 17377 | 2626 |
PPIB,TRIM41,ADAM10,ARID2,RPS6KA1,UROD,RRM1,FLOT1,CDIPT,TWF2,TCF19,EXT2,PIP4K2A,CHKA,CDK5,ZBTB45,C18orf32,SLC44A1,PHTF1,XPA,H2AFY,KIFAP3,GLTP,SPTSSA,SLC12A2,SLC35A1,STAU1,RFC3,POLR2L,ERF,BTG2,MFNG,TRIM28,FKBP3,NCDN,ECH1,MAPK3,TFEB,CHCHD3,TXNDC16,BIRC5,DHX16,TFDP1,EXOC4,H2AFX,ANP32E,SMAD1,HIGD2A,TUBB |
| 8.507e-05 | -9.37 | GSE43863_NAIVE_VS_MEMORY_TFH_CD4_TCELL_D150_LCMV_DN | MSigDB lists | GSE43863_NAIVE_VS_MEMORY_TFH_CD4_TCELL_D150_LCMV_DN | 185 | 48 | 17377 | 2626 |
SRM,URB2,B4GALT5,TRMT6,AGFG1,NUP205,CFLAR,FASTKD3,LYAR,MRPL50,ERH,DDX56,UBXN2A,HOMER1,NUS1,EIF2S2,NOL11,KLF16,PRDM4,NAA50,DDX31,CITED2,FTSJ3,SYTL3,SLC25A1,RBM15B,PLK3,LARS,MIOS,LAP3,IDH3A,WDR18,PCGF6,GTPBP4,ODC1,MAK16,MAT2A,USP36,UAP1,PSMD8,PTAR1,RWDD4,SLC16A1,RUVBL2,PPP5C,PITRM1,SLC25A33,CCDC137 |
| 8.507e-05 | -9.37 | GSE22432_CDC_VS_COMMON_DC_PROGENITOR_UP | MSigDB lists | GSE22432_CDC_VS_COMMON_DC_PROGENITOR_UP | 185 | 48 | 17377 | 2626 |
CKLF,CIB1,CERK,CHIC2,SIKE1,NOTCH2,CDC42SE2,MXD4,GYG1,MAPK14,SAFB2,SYNRG,ARID1B,UBLCP1,FERMT3,CAPN2,SH3BP1,WDR44,TBC1D14,SSBP3,RCSD1,CDKN1B,KCNAB2,TSHZ1,POU2AF1,BIRC3,TSPYL4,PARP4,NARF,MTMR6,RFC2,SMAP2,SH3GLB1,ARHGAP15,TFEB,JAK1,TXNDC16,TAB2,ACYP1,CSK,MYO18A,NRM,APPL2,GALNT10,TRAF5,RNF139,SNX14,ZBTB24 |
| 8.507e-05 | -9.37 | MCBRYAN_PUBERTAL_BREAST_6_7WK_UP | MSigDB lists | MCBRYAN_PUBERTAL_BREAST_6_7WK_UP | 185 | 48 | 17377 | 2626 |
PDCD6IP,KIAA0100,PDAP1,ANKH,SMC6,CSNK2A1,SMARCA4,UBE4A,MAPK14,ETS1,CNOT3,RAD23A,SPPL2A,APLP2,NFATC3,PTEN,IL6ST,DNM2,DAPK1,ARHGEF2,SLC38A10,CORO1A,GM2A,PRPF19,CYTH1,BRD4,TIMP2,AKT2,TAOK1,ATP6V0A1,LRP5,OGFR,RAB5B,DPYSL3,GNAS,UBTF,GALNT2,KEAP1,SEC61A1,SYNCRIP,HIPK2,NFIL3,ACLY,OGT,CANT1,RBBP4,PPP6R3,EGLN1 |
| 8.507e-05 | -9.37 | GSE28737_WT_VS_BCL6_KO_MARGINAL_ZONE_BCELL_DN | MSigDB lists | GSE28737_WT_VS_BCL6_KO_MARGINAL_ZONE_BCELL_DN | 185 | 48 | 17377 | 2626 |
PDCD6IP,SHPRH,ABCC10,ANKH,AGFG1,NHLRC3,CSNK1A1,MAN1A1,MOAP1,ABL2,FASTKD3,PPP1R3B,PHTF1,FEM1B,CGGBP1,FDFT1,PHF20L1,RHOA,KLF10,PRIM2,TACC1,NOA1,EMB,TLK1,MTMR12,DIDO1,RAB1A,FXR1,KLF6,MAK16,PICALM,TWISTNB,OPTN,IWS1,EPRS,CCDC14,ZNF689,BBX,TBPL1,FN3KRP,CNOT6,ROCK1,NCOA1,RBPJ,PREPL,FBXL3,ZMAT3,SVIP |
| 8.507e-05 | -9.37 | GSE44732_UNSTIM_VS_IL27_STIM_IMATURE_DC_UP | MSigDB lists | GSE44732_UNSTIM_VS_IL27_STIM_IMATURE_DC_UP | 185 | 48 | 17377 | 2626 |
CYTIP,PTMS,NCOR2,NDUFV2,TRIP10,GPBP1L1,UQCR10,EIF3D,GNE,OLA1,AGPAT1,STARD7,CREBL2,DUSP22,MAD2L2,RRP36,CFLAR,ZER1,ABL2,RAB8A,SUB1,TNFAIP8,RABGAP1L,MEGF8,BDH1,DDA1,TTC9C,GPD1L,DNMT1,PPA1,TERF2,NAGPA,RPRD1A,PRRC2A,RAB7A,GNG7,VDAC2,SHCBP1,TRIM28,IRF5,MAN2A2,PON2,NLRC5,FKBP5,ZNF598,USP53,LRP8,ZC3HC1 |
| 8.507e-05 | -9.37 | GSE22886_IGG_IGA_MEMORY_BCELL_VS_BM_PLASMA_CELL_UP | MSigDB lists | GSE22886_IGG_IGA_MEMORY_BCELL_VS_BM_PLASMA_CELL_UP | 185 | 48 | 17377 | 2626 |
KCTD7,PDCD6IP,CDC40,PPP1R12A,NACA,SLC2A1,TIA1,PAWR,NOTCH2,GGA2,DAZAP2,SNN,ATP6V1B2,PPP1R16B,GIT2,CDC73,RPL11,MAT2B,PDCD10,TNFAIP8,ARPC5,RPL17,HUWE1,ZCCHC2,PIGG,CORO1A,PIKFYVE,MORC3,ELOVL5,MAPRE2,SEPT9,SRSF5,SEPT7,API5,SF3A2,POLR2A,CAT,MKNK1,DGCR8,STAT6,SNAP23,STK38,QRSL1,NUP62,DDX5,MAPK1,MYL12B,SMAD4 |
| 8.507e-05 | -9.37 | GSE19198_CTRL_VS_IL21_TREATED_TCELL_6H_DN | MSigDB lists | GSE19198_CTRL_VS_IL21_TREATED_TCELL_6H_DN | 185 | 48 | 17377 | 2626 |
TCF12,SNX27,HECA,GNPDA1,TSC22D3,FLOT1,YTHDF3,ZFYVE21,THRAP3,TAF6L,GGA2,RLF,ZADH2,RUFY1,PITHD1,FANCI,MAN1A1,MOAP1,MTMR4,TBC1D14,KIF13B,SOCS6,TPST1,H2AFY,PIK3IP1,RNF135,LDLRAD3,DVL2,SAP30,DDX24,ELL2,RDH10,TOPORS,AMDHD2,WDR81,AZI2,RAB5B,ERC1,TPD52L2,ETS2,DUSP3,GADD45B,RNF38,ADAM9,FKBP5,RGL1,USF2,CAPN1 |
| 8.512e-05 | -9.37 | single-stranded telomeric DNA binding | molecular function | GO:0043047 | 12 | 8 | 17224 | 2647 |
TERF2IP,HNRNPA2B1,RPA2,NABP2,TERF1,POT1,RPA1,TERF2 |
| 8.513e-05 | -9.37 | GO_VACUOLAR_ACIDIFICATION | MSigDB lists | GO_VACUOLAR_ACIDIFICATION | 15 | 9 | 17377 | 2626 |
ATP6V0B,CLIC4,PPT1,ATP6V0A1,ATP6V0A2,ATP6V0C,CLN3,CLN6,ATP6V0E1 |
| 8.513e-05 | -9.37 | GO_SUMO_TRANSFERASE_ACTIVITY | MSigDB lists | GO_SUMO_TRANSFERASE_ACTIVITY | 15 | 9 | 17377 | 2626 |
MDM2,HDAC7,NSMCE2,PIAS2,KIAA1586,TOPORS,UBE2I,CBX4,CDKN2A |
| 8.518e-05 | -9.37 | KEGG_PROGESTERONE_MEDIATED_OOCYTE_MATURATION | MSigDB lists | KEGG_PROGESTERONE_MEDIATED_OOCYTE_MATURATION | 85 | 27 | 17377 | 2626 |
PLK1,AKT2,RPS6KA1,RAF1,ANAPC2,KRAS,PKMYT1,CDC23,CCNB1,PRKACA,MAPK14,PDE3B,MAD2L2,MAPK3,CCNA2,CDC16,CDC27,PIK3R2,ADCY9,ANAPC7,CDC25B,CDK2,GNAI2,CCNB2,MAPK1,ANAPC4,ADCY7 |
| 8.518e-05 | -9.37 | GO_DNA_TEMPLATED_TRANSCRIPTION_ELONGATION | MSigDB lists | GO_DNA_TEMPLATED_TRANSCRIPTION_ELONGATION | 85 | 27 | 17377 | 2626 |
CTDP1,POLR2I,POLR2G,POLR2L,POLR2K,ELL2,POLR2D,ELP4,RTF1,CDC73,TWISTNB,POLR2A,GTF2F1,SUPT16H,TAF2,UBTF,CCNK,PAF1,POLR2J,CD3EAP,TCEA1,TAF12,POLR1B,GTF2H2,ZNRD1,TAF6,SSRP1 |
| 8.525e-05 | -9.37 | FGF8 (fibroblast growth factor 8) | protein interactions | 2253 | 101 | 32 | 17029 | 2761 |
RPS15,CHERP,YTHDC2,BRIX1,CDK11B,KRR1,FGFR3,DDX56,STRBP,NVL,NOC2L,DDX31,MRPL40,ANKHD1,CDK12,NSUN4,DDX24,AATF,NOA1,NOL8,GTPBP4,BMS1,DHX57,ZFR,NSA2,UPF1,DAP3,WDR11,H2AFX,RBMS1,NKAPD1,PDCD11 |
| 8.538e-05 | -9.37 | Complex I biogenesis | REACTOME pathways | R-HSA-6799198 | 51 | 20 | 10287 | 1696 |
NDUFA5,NDUFV2,NDUFS1,NDUFB6,TIMMDC1,NDUFAF2,TMEM126B,NDUFA7,NDUFB1,NDUFS7,NDUFS4,NDUFAF6,NDUFV1,NDUFA2,NDUFB4,NDUFA11,NDUFB9,NDUFS8,NDUFS5,NDUFA3 |
| 8.588e-05 | -9.36 | Mitochondrial translation initiation | REACTOME pathways | R-HSA-5368286 | 87 | 29 | 10287 | 1696 |
MRPL9,MRPL42,MRPS2,MRPS15,MRPL39,MRPS26,MRPL12,MRPL43,MRPS10,MRPL16,MRPS14,MRPL19,MRPL50,MRPL2,DAP3,MRPL55,CHCHD1,MRPL27,MRPL34,MRPS27,MRPL54,MRPL48,MRPL40,MRPL11,MRPL21,MRPL13,MRPL3,MRPL32,MRPL57 |
| 8.588e-05 | -9.36 | Regulation of mitotic cell cycle | REACTOME pathways | R-HSA-453276 | 87 | 29 | 10287 | 1696 |
PLK1,PSMA8,PTTG1,PSMB7,PSMA1,CUL1,ANAPC2,AURKB,CDC23,CCNB1,PSMD9,PSMB9,PSMB3,PSMC4,FBXO5,PSMD2,PSMA6,CCNA2,CDC16,PSMD1,CDC27,RPS27A,PSMD8,PSMD3,ANAPC7,CDK2,UBE2C,PSMC1,ANAPC4 |
| 8.588e-05 | -9.36 | APC/C-mediated degradation of cell cycle proteins | REACTOME pathways | R-HSA-174143 | 87 | 29 | 10287 | 1696 |
PLK1,PSMA8,PTTG1,PSMB7,PSMA1,CUL1,ANAPC2,AURKB,CDC23,CCNB1,PSMD9,PSMB9,PSMB3,PSMC4,FBXO5,PSMD2,PSMA6,CCNA2,CDC16,PSMD1,CDC27,RPS27A,PSMD8,PSMD3,ANAPC7,CDK2,UBE2C,PSMC1,ANAPC4 |
| 8.594e-05 | -9.36 | SKI (SKI proto-oncogene) | protein interactions | 6497 | 123 | 37 | 17029 | 2761 |
AGRN,MECP2,ATP5F1B,UBE2I,PABPC4,RB1,PCNA,ATP2A2,HADHB,MOB1A,MVP,PABPC1,HNRNPM,RB1CC1,AKT2,PRKDC,LDHA,TUFM,PLEC,SLC25A5,TRIM28,PRDX1,SMAD2,ATP1A1,AHNAK,HIPK2,AXIN1,STK38,PML,SIAH2,DDX5,ACTB,ATP5F1A,SMAD1,SMAD4,TUBB,PFKP |
| 8.594e-05 | -9.36 | PSMC6 (proteasome 26S subunit, ATPase 6) | protein interactions | 5706 | 123 | 37 | 17029 | 2761 |
CYLD,EWSR1,PMS2,PSMD9,UBLCP1,PTPN2,PSMD2,MDM2,PSMD1,PSMA6,SIAH1,HUWE1,UCHL5,RAD23B,CDC5L,TXNL1,CCT2,STAU1,PSMA8,PSMB7,PSMA1,DNAJA1,BRCA1,PSMB9,RFC2,ABCF1,PSMB3,PSMC4,PPP2CA,SEC61A1,QARS,PSMD3,PSMD8,UBE2C,ECPAS,CDK2,PSMC1 |
| 8.595e-05 | -9.36 | SLC25A5 (solute carrier family 25 member 5) | protein interactions | 292 | 141 | 41 | 17029 | 2761 |
COX15,TOMM20,CYLD,RPS2,RPL15,CUL1,SDHA,LMNA,RPL11,WWP2,RPL23A,NDUFS4,RPN1,EIF4A3,HUWE1,PTEN,MCM5,ZNF746,TARDBP,RPL19,ATP6V0D1,ASB6,CDC37,STAU1,RHOA,VDAC2,CUL3,RPL6,RPS24,ADRB2,VDAC1,MCM2,RPSA,CAND1,SMAD2,TONSL,FUS,COPS6,CLN3,SMURF1,ANXA11 |
| 8.595e-05 | -9.36 | P4HB (prolyl 4-hydroxylase subunit beta) | protein interactions | 5034 | 141 | 41 | 17029 | 2761 |
PPIB,EWSR1,GXYLT1,PRKCSH,SUZ12,AGO2,RBM8A,TKT,ATP5F1B,UBQLN2,GLRX3,PSMD9,USP5,PRNP,CEP104,PCNA,CLIC4,PPME1,BCAP29,LMAN1,PDIA6,ATF2,PABPC1,TXNL1,NEK7,ERO1A,CUL3,EZR,BRCA1,MCM2,SYMPK,CLNS1A,TRIM4,TPD52L2,SURF4,CCDC6,SAFB,H2AFX,ATP5F1A,CDK2,ARRB2 |
| 8.598e-05 | -9.36 | GO_IRE1_MEDIATED_UNFOLDED_PROTEIN_RESPONSE | MSigDB lists | GO_IRE1_MEDIATED_UNFOLDED_PROTEIN_RESPONSE | 55 | 20 | 17377 | 2626 |
SEC61B,ADD1,SEC61G,CXXC1,SYVN1,SERP1,DNAJB9,LMNA,SSR1,YIF1A,SEC31A,SHC1,SEC61A1,TATDN2,ASNA1,PDIA6,CTDSP2,ATP6V0D1,PREB,DCTN1 |
| 8.627e-05 | -9.36 | WEE1 (WEE1 G2 checkpoint kinase) | protein interactions | 7465 | 84 | 28 | 17029 | 2761 |
PLK1,BRD4,DENND4C,CDCA3,TOP3A,RRM2,CSNK2A1,CDC6,BRCA1,BLM,MCM2,CSNK1A1,PCBP1,CDC73,RB1,BRPF3,PIN1,KIF13B,IMPDH1,CDKN1B,XRCC3,YWHAZ,CHEK2,CDK2,ARRB2,SMURF1,SMAD4,CDK12 |
| 8.646e-05 | -9.36 | nuclear chromosome, telomeric region | cellular component | GO:0000784 | 124 | 35 | 18223 | 2701 |
THOC1,ORC1,CDC73,WRNIP1,TERF2IP,RPA2,PCNA,SP100,MCM5,MSH2,NABP1,NABP2,H2AFY,ORC3,TERF2,TELO2,ERCC1,PRKDC,WDR82,DCLRE1C,MEN1,MCM2,GAR1,RPA1,XRCC5,CBX3,UPF1,PML,XRCC3,H3F3A,TERF1,PURA,POT1,RAD51D,DDB1 |
| 8.662e-05 | -9.35 | GO_RNA_POLYMERASE_ACTIVITY | MSigDB lists | GO_RNA_POLYMERASE_ACTIVITY | 43 | 17 | 17377 | 2626 |
POLR2I,POLR2G,POLR2L,PRIM2,POLR2K,POLR2D,POLR3GL,POLR3K,TWISTNB,POLR2A,PRIM1,POLR2J,CD3EAP,CRCP,RPAP1,POLR1B,ZNRD1 |
| 8.662e-05 | -9.35 | REACTOME_TRANSCRIPTION_COUPLED_NER_TC_NER | MSigDB lists | REACTOME_TRANSCRIPTION_COUPLED_NER_TC_NER | 43 | 17 | 17377 | 2626 |
ERCC1,RFC3,POLR2I,POLR2G,POLR2L,POLR2K,XAB2,POLR2D,RFC2,POLR2A,RPA1,RPA2,PCNA,POLR2J,POLE,TCEA1,GTF2H2 |
| 8.662e-05 | -9.35 | PID_PLK1_PATHWAY | MSigDB lists | PID_PLK1_PATHWAY | 43 | 17 | 17377 | 2626 |
PLK1,KIF2A,PPP2CA,RHOA,PPP1R12A,CLSPN,GOLGA2,GORASP1,ODF2,TPX2,PRC1,CDC25B,CCNB1,RAB1A,BORA,NUDC,FBXO5 |
| 8.679e-05 | -9.35 | GTP hydrolysis and joining of the 60S ribosomal subunit | REACTOME pathways | R-HSA-72706 | 117 | 36 | 10287 | 1696 |
RPS15,RPS2,RPLP2,EIF3D,RPL15,RPL11,RPL23A,EIF2S2,RPL17,RPL19,EIF5,RPL22L1,EIF3L,RPL29,RPL35,RPL38,RPL6,RPS10,RPL8,RPS24,RPL27A,EIF4H,EIF3G,RPS9,EIF3H,EIF3A,RPSA,RPL36,EIF3K,RPL37,RPL32,RPS27A,RPS14,RPLP1,FAU,RPS26 |
| 8.679e-05 | -9.35 | L13a-mediated translational silencing of Ceruloplasmin expression | REACTOME pathways | R-HSA-156827 | 117 | 36 | 10287 | 1696 |
RPS15,RPS2,RPLP2,EIF3D,RPL15,RPL11,RPL23A,EIF2S2,RPL17,RPL19,RPL22L1,PABPC1,EIF3L,RPL29,RPL35,RPL38,RPL6,RPS10,RPL8,RPS24,RPL27A,EIF4H,EIF3G,RPS9,EIF3H,EIF3A,RPSA,RPL36,EIF3K,RPL37,RPL32,RPS27A,RPS14,RPLP1,FAU,RPS26 |
| 8.701e-05 | -9.35 | regulation of exit from mitosis | biological process | GO:0007096 | 18 | 10 | 17256 | 2622 |
TGFB1,PPP1R9B,PHB2,CDCA5,CDKN1B,KNTC1,SIRT2,ANLN,CDC23,UBE2C |
| 8.783e-05 | -9.34 | HSPA8 (heat shock protein family A (Hsp70) member 8) | protein interactions | 3312 | 535 | 120 | 17029 | 2761 |
IER2,NPHP4,CYLD,ST13,IVNS1ABP,POC1A,FLYWCH2,DYNLL1,RAF1,SUMO2,CHD1L,CUL1,EBNA1BP2,TAF6L,UBQLN2,STMN1,EDRF1,APP,RAD23A,CSDE1,ABL2,MDM2,SHC1,EIF4A3,GOT2,THAP4,PPME1,DUT,PIK3R2,RPAP1,CDKN1B,CRY2,TARDBP,MAVS,TECR,LMAN1,ABI1,TACC3,CDC37,CDC5L,MAPRE2,RBX1,VHL,RNF25,CUL3,RNPS1,DNAJC9,ATXN1,WDR82,MCL1,NFATC2,BRCA1,DNAJA1,MCM2,FOXRED1,DHX57,NECAP2,HSPA4,DGCR8,CAMKMT,FUS,COPS6,PPP5C,ARRB2,SMURF1,CSNK1D,PARD3,TUBB,DNAJC2,HSPH1,DNAJB2,NACA,AGPAT3,CYCS,DNAJB1,CDK11B,RGS2,CDC73,TUBGCP2,SRRT,HAUS2,C12orf10,RPA2,RB1,ERH,FGFR3,NUS1,PTEN,PPP1R8,MCM5,SEC24C,AHSA1,CAPZA1,CNN2,MVP,PABPC1,PDPK1,STAU1,NOA1,PRKDC,RPL8,METTL22,MEN1,MAP2K2,SF3A2,ISG15,RPA1,CAND1,SEC31A,DERL1,HGS,HSPBP1,POLE,CDCA5,LRPPRC,NAXE,ASNA1,CDK2,FAF1,CDKN2A |
| 8.799e-05 | -9.34 | GARGALOVIC_RESPONSE_TO_OXIDIZED_PHOSPHOLIPIDS_TURQUOISE_DN | MSigDB lists | GARGALOVIC_RESPONSE_TO_OXIDIZED_PHOSPHOLIPIDS_TURQUOISE_DN | 51 | 19 | 17377 | 2626 |
PLK1,DDX28,CDK2AP2,MKI67,KIF15,CCNF,ZNF174,KIFC1,CDKN2C,CCNA2,NEIL3,PPIL2,PRMT7,GEMIN6,RRS1,TTLL12,OSGEPL1,ESPL1,TACC3 |
| 8.842e-05 | -9.33 | generation of precursor metabolites and energy | biological process | GO:0006091 | 388 | 87 | 17256 | 2622 |
COX15,NDUFA5,SUCLG1,NDUFB6,UGP2,NDUFAF2,GNPDA1,UQCR10,MDH2,ADPGK,GYG1,GLRX3,ATP5PF,SDHA,MTFR1L,NRF1,IL6ST,CS,AKR1B1,SUCLG2,NDUFB9,AKT2,COQ10B,IDH3A,OGDH,NDUFA7,NDUFB1,TAZ,POLG2,STOML2,RPS27A,NDUFA11,COX5A,DHTKD1,UQCRH,PFKP,NDUFV2,COX5B,GALK1,NDUFS1,PPP1R2,MECP2,SLC25A12,NDUFA4,COX4I1,CYCS,ATP5F1B,NDUFS7,NDUFS4,FASTKD3,PPP1R3B,NDUFV1,NDUFA2,NDUFB4,BDH1,MSH2,NDUFS8,CYC1,NDUFA3,PHKG2,ATP5IF1,TSTA3,RB1CC1,AACS,NQO2,MTFR2,LDHA,TBRG4,ADSL,ATP5MF,PKM,CYB5A,GNAS,CAT,SDHB,ATP5MC3,ACOX1,COX7A2L,COX8A,ACAT1,MDH1,NDUFS5,ATP5F1A,GPI,IDH3B,NIPSNAP2,PGAM1 |
| 8.870e-05 | -9.33 | GO_REGULATION_OF_CELLULAR_RESPONSE_TO_HEAT | MSigDB lists | GO_REGULATION_OF_CELLULAR_RESPONSE_TO_HEAT | 72 | 24 | 17377 | 2626 |
HSPH1,DNAJC2,NUP188,RAE1,NUP54,NUP155,AKT1S1,DNAJB1,NUP205,HSPA1B,MAPK3,RPA1,RPA2,NUP210,NUP107,NUP62,NUP153,PTGES3,MAPK1,NUP85,SEH1L,CAMK2G,AAAS,MLST8 |
| 8.890e-05 | -9.33 | DENR (density regulated re-initiation and release factor) | protein interactions | 8562 | 48 | 19 | 17029 | 2761 |
EWSR1,RB1CC1,UBXN1,VDAC2,DOCK11,BTBD1,EEF2K,MCTS1,AMZ2,HNRNPA2B1,EIF2D,DHTKD1,ATG13,COPS7B,COPS6,TALDO1,XRCC4,PDLIM5,NSUN4 |
| 8.897e-05 | -9.33 | histone H3-K4 trimethylation | biological process | GO:0080182 | 15 | 9 | 17256 | 2622 |
TET3,ZNF335,OGT,CTR9,KMT2B,RTF1,WDR82,BEND3,ARID4A |
| 8.922e-05 | -9.32 | neutrophil degranulation | biological process | GO:0043312 | 481 | 104 | 17256 | 2622 |
RHOG,ADA2,RAB14,ADAM10,DYNLL1,RAC1,HEXB,NIT2,NHLRC3,GYG1,MAPK14,KCMF1,CMTM6,CPNE3,PA2G4,RAP1A,PSMD1,AP1M1,BRI3,TMBIM1,GM2A,KCNAB2,ENPP4,CPNE1,CCT2,TIMP2,NRAS,RAB7A,ARHGAP45,PPIE,CYSTM1,PSMB7,ATP6V0A1,RAB5B,TOLLIP,ALDH3B1,DSN1,AGPAT2,DDOST,SURF4,RAB24,PSMD3,CAB39,CANT1,ATP6V0C,ROCK1,PDXK,LTA4H,MAPK1,CAPN1,TUBB,SVIP,MIF,DNAJC5,GMFG,MANBA,PDAP1,LAMTOR3,B4GALT1,ASAH1,CDK13,MAN2B1,RAB6A,PSEN1,TMEM179B,GNS,CD59,PSMD2,CTSS,ARPC5,HUWE1,OSTF1,CNN2,MVP,LPCAT1,SPTAN1,CYFIP1,FTL,MLEC,RHOA,CREG1,C1orf35,HEBP2,PKM,ARMC8,CCT8,NEU1,HSPA1B,CAND1,XRCC5,CAT,RAB18,ATP6V1D,MAGT1,GOLGA7,SNAP29,SNAP23,ACLY,PGRMC1,IMPDH1,CTSA,PSAP,GPI,PGAM1 |
| 8.922e-05 | -9.32 | regulation of intracellular steroid hormone receptor signaling pathway | biological process | GO:0033143 | 76 | 25 | 17256 | 2622 |
RHOA,RWDD1,PHB2,WBP2,SMARCA4,BRCA1,UBE2I,PRMT2,SAFB2,CBFB,PAGR1,PARK7,DDRGK1,CNOT9,AXIN1,UBA5,ARNTL,BUD31,PIAS2,DDX5,CRY2,PPP5C,RNF14,ARRB2,CARM1 |
| 8.924e-05 | -9.32 | extracellular organelle | cellular component | GO:0043230 | 2142 | 377 | 18223 | 2701 |
RAB14,TXN,PDCD6IP,H2AFZ,LUZP1,ADAM10,HEXB,TMEM109,NANS,PLXNA1,PARK7,RPL23A,NAPG,PA2G4,RAB4A,AP1M1,DNM2,SLC26A2,MOB1A,MGAT5,PCBP2,RHOBTB3,NRAS,GNG7,PPFIA3,SMC2,NUTF2,GALNT7,RAB22A,RAB2B,ARF4,AHNAK,WAS,RPS27A,RPS14,PTER,PRDX5,ITGB1,ATP6V0C,PFKP,ANXA11,SVIP,PPIB,HSPH1,HLA-E,RHOC,CUTA,B4GALT1,MAN2B1,ITGB5,VPS25,MYL6B,GNS,CD59,ARPC5,SNX18,MEGF8,ATIC,GEMIN4,MVP,GNAI2,PABPC1,PPA1,CYFIP1,FTL,CPQ,PRRC2A,WDR1,MAN1B1,PIP4K2C,ITM2A,EXOSC9,PLEC,CAPZA2,PKM,PTTG1IP,CYFIP2,CCT8,RHOB,PSMB3,FAS,CAT,ADSS,PTPRF,SCARB2,TXNDC16,CSK,RBMX,ACLY,APPL2,MDH1,GPI,CFAP20,HEXA,RHOG,RAB11B,TRIP10,RAC1,ACTR3,OLA1,MYH9,NIT2,PRKACA,SAFB2,STMN1,CPNE3,APP,GNB2,RAB21,APLP2,AHCTF1,RALB,DUT,TALDO1,GPD1L,TMBIM1,CFL1,ATP6V1G1,GPX4,CPNE1,ENPP4,CCT2,TAOK1,CUL3,ATP6V0A1,DNAJA1,GSTCD,RAB1A,PSMB9,H2AFV,PPP2CA,CHCHD3,ALDH3B1,HSPA4,HINT1,H2AFX,PDXK,B4GALT3,TUBB,GALK1,RPS2,SCAMP3,ANXA6,FLOT1,TKT,ABHD14B,ATP5F1B,SPR,PMVK,RAB11A,TUT4,WWP2,MAT2B,CAPN2,PSMD2,PDCD10,CLIC4,ITGB8,HUWE1,AHSA1,ARF5,FUT8,NAA50,ANXA5,TAGLN2,S100A6,HNRNPM,LYPLA2,SPTAN1,LDHB,STAU1,TNFAIP3,STRIP1,PARP4,LDHA,HEBP2,ECH1,PRDX1,PLD3,NUCB1,SGSH,HGS,WNT5B,DBI,CAPN7,FAM3C,NAXE,LY75,ASNA1,DDX5,PSAP,CD81,YWHAH,DDB1,UBL3,ST13,COPA,AGRN,GNPDA1,FAM129A,MOGS,SND1,TAF6L,PRNP,RAB8A,PCNA,RAP1A,CDC42,GOT2,RAB35,IL6ST,ZNHIT6,DPYSL2,SLC44A1,SRI,AKR1B1,RP2,CARMIL1,CDC37,COPS8,LAP3,MBLAC2,CYSTM1,EZR,ARHGDIB,UBE2V1,RAB5B,RHEB,UEVLD,NAGLU,CAB39,ADAM9,ARRDC1,ACTB,STK11,CLU,VPS4A,RPS26,MYL12B,CAPN1,UBE2D3,UFC1,LAMTOR3,CIB1,ASAH1,RACGAP1,DNAJB1,NCKAP1,THRAP3,RAB6A,EPHX2,SUB1,VASP,CAPZA1,YBX1,AHCY,TMEM8A,SLC12A2,HDHD2,ATP6V0D1,ABCC1,ALDH9A1,TSTA3,CREG1,NQO2,GBA,PSMA1,SEPT7,ARPC1A,APPL1,CAND1,GNAS,GOLGA4,SNAP23,SLC16A1,YWHAZ,DNPH1,CTSA,PITPNA,RUVBL2,ATP5F1A,EHD4,N4BP2L2,WASF2,CHMP2A,UGP2,RPLP2,MDH2,SLC2A1,ATP6V1B2,LYN,PCBP1,TWF2,EXT2,RPL11,HNRNPA2B1,NRF1,PSMA6,IARS,CS,PDCD2,CORO1A,CYB5R1,MINPP1,AHCYL1,LMAN1,PDIA6,ABI1,GM2A,CHP1,PSMA8,PPT1,RAB7A,BTG2,GLO1,VDAC1,CHMP2B,TOLLIP,PEF1,RPS9,RPSA,EIF3H,GLOD4,ATP1A1,PSMD3,CANT1,CHMP4B,FKBP5,SCARB1,H3F3A,SMURF1,LTA4H,CHID1,MIF,KIF3B,TOR3A,DCTN2,AGO2,ARF1,SLC12A9,DNAJB9,TFRC,MAN1A1,SPPL2A,FERMT3,GSTK1,GART,SLC1A4,H2AFY,FBL,MYO5A,SLC25A1,RHOA,ACP2,FAM49B,CSRP1,TUFM,ARHGEF12,NDRG3,NEU1,TARS,DDX23,HSPA1B,CTSL,ATP6V1D,PDCD6,ATAD2,GOLGA7,PLAA,GLG1,ACAT1,PKD2,ATP6V1C1,PLOD3,ARHGAP23,PGAM1,SAT2 |
| 8.926e-05 | -9.32 | FORTSCHEGGER_PHF8_TARGETS_DN | MSigDB lists | FORTSCHEGGER_PHF8_TARGETS_DN | 715 | 145 | 17377 | 2626 |
UBL3,TMEM184B,AGPAT1,ABCB10,CCNL2,OAT,ELMOD2,CMTM6,SLC25A37,SSR1,C14orf119,FANCL,DLG5,ABL2,NAPG,AP3S2,DPYSL2,RABGAP1L,IMPAD1,PHTF1,RP2,SPTSSA,MTPN,SEH1L,BAK1,TRIM8,OSBP2,APH1A,ZBED5,GMFB,ARHGDIB,UTP3,USP22,STX16,ARF4,OPTN,TRIM4,TRAM2,HSPB11,AHNAK,RPS14,MYO18A,FBXL3,NXT2,DDX58,NSMCE4A,MAPRE1,PPP1R12A,POLR2K,TATDN3,KCTD17,CIB1,PM20D2,CHKA,CD59,SLC31A1,MEGF8,XPA,MVP,LPCAT1,ELL2,ERLIN1,ZMYND11,DCTD,RTF1,MAP7D1,PLEC,C9orf40,ARPC1A,ISG15,HMGN2,NAP1L1,NSF,DCAF11,FN3KRP,CNOT6,TMEM159,MYO9A,BTBD10,ZC3HAV1,EGLN1,REPS2,CAST,UROD,STARD7,RMI2,SLC39A13,RRAGC,TBC1D13,CREBL2,BCL2L1,ADCY9,EFCAB11,MRPS27,METTL9,TMBIM1,RNF169,CGGBP1,PPP1R18,BIRC3,FAM172A,HMGN4,EID1,IDH3A,NUP155,RAB1A,AP4E1,ERC1,BTBD1,SRSF1,HNRNPR,RWDD4,TUBB,PKP4,MZT1,RAE1,B4GALT5,AGPAT3,GFM2,XPR1,GTPBP3,CTSS,ITGB8,FUT8,YIF1B,S100A6,PAQR6,PDPK1,MOB4,RPRD1A,DCAF6,HEMK1,TACC1,KCNQ1,RPL27A,KLF6,NEU1,FBXO21,GNA12,INF2,CCDC6,OAZ2,CDCA7L,COX8A,MRFAP1L1 |
| 8.927e-05 | -9.32 | Diseases of signal transduction | REACTOME pathways | R-HSA-5663202 | 370 | 89 | 10287 | 1696 |
MIB2,CCNC,FGFR1OP,TSC2,NF1,ADAM10,RAF1,CUL1,SND1,VAV1,RAP1A,MDM2,PSMD1,PSMA6,SHC1,PIK3R2,CLCN6,CDKN1B,FGFR1OP2,CDC37,MLST8,NRAS,POLR2L,POLR2G,PSMA8,APH1A,RBX1,AKT2,PSMB7,POLR2D,LRP5,PSMB9,PPP2CA,SMAD2,PPP2R5A,RPS27A,PSMD8,PSMD3,AXIN1,MYO18A,SEL1L,STAT1,ARRB2,MAPK1,PSMC1,SMAD4,HDAC2,NCOR2,AGTRAP,POLR2K,TRAK1,BRAP,AKT1S1,PSMD9,APH1B,CSNK1A1,FOXO3,FZD6,LMNA,GTF2F1,FKBP1A,PSMD2,FGFR3,HDAC7,PTPN11,CREB1,MAML1,STAT3,TGFB1,PDPK1,ADAM17,POLR2I,AGGF1,KAT2A,PSMA1,KRAS,SYVN1,FXR1,MACF1,MAP2K2,POLR2A,PSMB3,MAPK3,PSMC4,POLR2J,CSK,RBPJ,HRAS,ZC3HAV1 |
| 8.965e-05 | -9.32 | Spitz | COSMIC cancer mutations | Spitz | 25 | 12 | 17385 | 2587 |
KIF5B,PWWP2A,NRAS,ZCCHC8,KRAS,ERC1,HRAS,HLA-A,CDKN2A,MYO5A,LMNA,DCTN1 |
| 9.009e-05 | -9.31 | SUPT16H (SPT16 homolog, facilitates chromatin remodeling subunit) | protein interactions | 11198 | 155 | 44 | 17029 | 2761 |
COX15,EWSR1,SUMO2,CHD1L,PRKAA1,CSNK2A1,USP39,TOP2B,CNTROB,KRI1,RPA2,MSH2,CTR9,CDK12,MSH6,HNRNPM,DCTN1,SRPK2,FYTTD1,CUL3,SREK1,RTF1,PRPF3,BRCA1,VDAC1,CDK11A,DHX15,SUPT16H,IWS1,CAND1,XRCC5,PAF1,NAP1L1,RBM25,TONSL,H2AFX,HMGB2,WDR76,H3F3A,CDK2,CD81,IFI16,PRPF4B,SSRP1 |
| 9.014e-05 | -9.31 | MAGEA1 (MAGE family member A1) | protein interactions | 4100 | 80 | 27 | 17029 | 2761 |
TRIM41,NSMCE4A,TRIM8,DCAF6,EID1,SELPLG,STRN4,PCGF6,EIF4G2,RCOR3,SRRT,HLA-A,MEAF6,MIEF1,DST,HLA-B,DAP3,PDCD6,HUWE1,CCDC14,BDH1,PRDX5,SH3GLB2,TOP1MT,LRSAM1,ANKHD1,ZNF564 |
| 9.014e-05 | -9.31 | RPL10L (ribosomal protein L10 like) | protein interactions | 140801 | 80 | 27 | 17029 | 2761 |
RPS15,RPS2,RPL35,RPS10,RPL6,RPL38,RPL8,RPL15,CUL1,RPS24,MCM2,RPL27A,RPSA,RPL11,RPA1,RPL36,RPL23A,CAND1,RPA2,RPS27A,RPL17,RPS14,ZNF746,ATP6V0A2,RPL19,CDK2,RPS26 |
| 9.024e-05 | -9.31 | PDGF Pathway | WikiPathways | WP2526 | 38 | 16 | 5312 | 837 |
VAV1,RHOA,CDC42,JAK1,SHC1,RAF1,RAC1,VAV2,PTPN11,STAT1,ARFIP2,ELK1,STAT3,MAPK1,HRAS,MAPK3 |
| 9.048e-05 | -9.31 | BRIX1 (BRX1, biogenesis of ribosomes) | protein interactions | 55299 | 110 | 34 | 17029 | 2761 |
NIFK,NOP2,MECP2,CUL1,EBNA1BP2,RBM4,PABPC4,RPL11,PTPN2,LYAR,DDX56,RBM34,FBL,ZC3H3,PABPC1,FTSJ3,PPAN,NOL12,STAU1,DDX24,AATF,GTPBP4,UTP15,CUL3,RPL6,KRAS,MAK16,CAND1,NSA2,DGCR8,RRS1,ZC3HAV1,IFI16,GPATCH4 |
| 9.054e-05 | -9.31 | GO_HELICASE_ACTIVITY | MSigDB lists | GO_HELICASE_ACTIVITY | 146 | 40 | 17377 | 2626 |
DDX58,RECQL,DDX47,SHPRH,CHD1L,YTHDC2,DHX9,DHX8,SMARCA4,BLM,CHD1,DDX56,EIF4A3,MCM5,DDX31,GINS1,DDX28,SNRNP200,DDX24,BTAF1,HELB,DHX29,DDX20,MCM2,DDX39A,EIF4H,DHX15,DHX57,GINS4,RAD54B,DDX23,DDX17,XRCC5,UPF1,DHX16,CHD3,DDX5,RUVBL2,DDX52,DDX42 |
| 9.054e-05 | -9.31 | WHITFIELD_CELL_CYCLE_S | MSigDB lists | WHITFIELD_CELL_CYCLE_S | 146 | 40 | 17377 | 2626 |
UBL3,GCLM,RRM1,BLM,RMI1,FANCI,MBD4,RPA2,SHC1,INTS7,NT5DC1,PHTF1,CENPM,ORC3,ABCC5,SRSF10,CDKN2AIP,RHOBTB3,PRIM2,KAT2A,RAD51AP1,ZBED5,RRM2,BRCA1,PKMYT1,SRSF5,RFC2,ASF1B,MASTL,PRIM1,ATAD2,RAD18,CERS6,CCDC14,GOLGA8A,CDCA5,PTAR1,OGT,DYNC1LI2,SVIP |
| 9.069e-05 | -9.31 | AFFAR_YY1_TARGETS_DN | MSigDB lists | AFFAR_YY1_TARGETS_DN | 226 | 56 | 17377 | 2626 |
DNAJC2,FOXM1,CHTF18,CDT1,ANKH,CDCA3,KIF23,RACGAP1,SLC29A1,KIF2C,PSEN1,NCAPG,STMN1,TTF1,MRPL19,TFAP4,VAV1,CCNA2,SUV39H2,MCM5,DUT,PRC1,MSH2,AXIN2,KIF22,CREB1,ALDH18A1,SLC35C2,TACC3,FDFT1,NIPSNAP1,ADCY7,PLK1,TK1,NASP,ASPM,NSDHL,RAD51AP1,MKI67,CDC6,AURKB,SMC2,SHCBP1,SLC25A5,API5,MTHFD2,RAD18,BIRC5,SOCS4,HMGB2,ANP32E,SCARB1,RBBP4,CCNB2,XRCC4,TERF1 |
| 9.127e-05 | -9.30 | CYB5B (cytochrome b5 type B) | protein interactions | 80777 | 37 | 16 | 17029 | 2761 |
CCT2,COX15,MRPL42,PHB2,TMEM216,NDUFA4,CYCS,DUSP22,APP,LMNA,STOML2,SEC31A,ATP1A1,CORO1C,UCHL5,CYB5R1 |
| 9.127e-05 | -9.30 | EIF1B (eukaryotic translation initiation factor 1B) | protein interactions | 10289 | 37 | 16 | 17029 | 2761 |
EIF3K,ERH,EIF3L,RAB7A,EIF3D,EIF2D,ACTR3,DHX9,ATXN1,ACAT1,TAGLN2,RPS9,EIF3G,DVL2,EIF3H,EIF3A |
| 9.127e-05 | -9.30 | CPLX1 (complexin 1) | protein interactions | 10815 | 37 | 16 | 17029 | 2761 |
AGTRAP,NENF,GLO1,POMP,GGA2,NDRG3,PSMD9,STAM,SNRPA,PFDN5,PSMD2,SEC24C,KHSRP,TAGLN2,TACC3,RNF114 |
| 9.153e-05 | -9.30 | CISD1 (CDGSH iron sulfur domain 1) | protein interactions | 55847 | 30 | 14 | 17029 | 2761 |
SDHB,PPIB,NDUFA2,RPL6,VDAC2,NDUFA4,COX4I1,MTX1,TECR,TOMM40,VDAC1,ATP6V1C1,BCAP31,ANXA11 |
| 9.245e-05 | -9.29 | MULLIGHAN_MLL_SIGNATURE_1_UP | MSigDB lists | MULLIGHAN_MLL_SIGNATURE_1_UP | 358 | 81 | 17377 | 2626 |
PLXNC1,RPS6KA1,DYNLL1,TOR1AIP1,HEXB,TGOLN2,SAFB2,COMMD8,REPS1,RBM23,NUP210,TIMM23,ATG3,ADCY9,MRPL34,DNM2,PARL,CEP63,CLTB,OGG1,ADCY7,PPIF,SELPLG,FRAT2,HTATIP2,EAF2,TOLLIP,CBFB,CHD3,SH3GLB2,CLN3,ATP6V0E1,OAZ1,NXT2,SEPHS2,TOR3A,KLC1,B4GALT1,RAB6A,PSEN1,NDUFS7,SAC3D1,GNS,KRI1,PTPN2,SNRNP25,MLX,MED8,SLC1A4,TANK,RRBP1,ZDHHC13,TNPO3,GTSE1,CNPY3,LPCAT1,S100A6,NAGPA,ABHD2,KIAA0930,ADRB2,COMMD4,RHOT2,PRDX1,FADD,DDX23,MYO1F,TFEB,CAT,SDHB,PLD3,GNA12,UPF1,POLR2J,OSBPL8,COX8A,CEBPG,GLG1,PITPNA,NUP62,CTSA |
| 9.259e-05 | -9.29 | adrenal_gland-adrenal_gland-adrenal_cortical_carcinoma | COSMIC cancer mutations | adrenal_gland-adrenal_gland-adrenal_cortical_carcinoma | 36 | 15 | 17385 | 2587 |
GNAS,RB1,DNMT3A,NRAS,NF1,PTEN,SF3B1,AXIN1,MSH2,STK11,KRAS,H3F3A,MEN1,HRAS,CDKN2A |
| 9.279e-05 | -9.29 | GO_DNA_CONFORMATION_CHANGE | MSigDB lists | GO_DNA_CONFORMATION_CHANGE | 252 | 61 | 17377 | 2626 |
RECQL,ASH1L,HJURP,UBN1,SHPRH,CHD1L,DHX9,CTCF,TOP2B,BLM,CCNB1,NCAPG,CHD1,OIP5,MCM5,AKAP8,RAD23B,XPA,NOC2L,H2AFY,NAP1L4,CENPM,TOP1MT,GTF2H2,TNRC18,SMC4,HP1BP3,GINS1,NASP,TSPYL4,RBX1,HELB,TOP3A,NUSAP1,SMC2,MCM2,ASF1B,GINS4,RAD54B,CHAF1A,XRCC5,PAF1,HHEX,NAP1L1,BRD2,RPS27A,CHD3,CDCA5,H2AFX,HMGB2,CABIN1,CENPT,RUVBL2,H3F3A,RBBP4,NAA60,POT1,PURA,IPO4,DDB1,CDKN2A |
| 9.357e-05 | -9.28 | KIF2C (kinesin family member 2C) | protein interactions | 11004 | 76 | 26 | 17029 | 2761 |
BCCIP,PLK1,MBD1,MAPRE1,WDYHV1,VHL,TEX10,WDR18,CDCA8,KRAS,NFATC2,KIF2C,WDR5,APP,GTF2F1,KIF2A,KIF18B,ADAM9,RBPJ,WDR62,SGF29,ESPL1,PCBP2,SMC4,DCTN1,CDC5L |
| 9.357e-05 | -9.28 | RBM10 (RNA binding motif protein 10) | protein interactions | 8241 | 76 | 26 | 17029 | 2761 |
UBQLN4,CYLD,SRSF6,CUL3,SREK1,CSNK2A1,WDR82,RBM4,SF3A2,DHX15,LMNA,RPA1,RBM17,RPA2,SUGP1,SYNCRIP,EIF4A3,HUWE1,AHSA1,U2SURP,DDX5,XRCC3,ARRB2,SMURF1,CCAR1,PRPF19 |
| 9.378e-05 | -9.27 | MCBRYAN_PUBERTAL_BREAST_5_6WK_DN | MSigDB lists | MCBRYAN_PUBERTAL_BREAST_5_6WK_DN | 127 | 36 | 17377 | 2626 |
DNMT3A,KIAA0100,PDAP1,SMC6,CSNK2A1,SMARCA4,THRAP3,MAPK14,CNOT3,RAD23A,SPPL2A,NFATC3,PTEN,IL6ST,DAPK1,ARHGEF2,SLC38A10,PRPF19,SRPK2,CYTH1,BRD4,HEMK1,AKT2,TAOK1,SREK1,OGFR,DPYSL3,GNAS,KEAP1,SEC61A1,OGT,ACLY,RBBP4,PPP6R3,FUBP1,EGLN1 |
| 9.419e-05 | -9.27 | RELB (RELB proto-oncogene, NF-kB subunit) | protein interactions | 5971 | 52 | 20 | 17029 | 2761 |
COMMD10,SUZ12,RAC1,SMARCA4,COMMD5,COMMD4,COMMD8,CBX3,CTSL,KLHL20,NEK6,CTBS,BUD31,KPNA2,YY1,USP11,STAT3,SMARCE1,DNMT1,SMARCD1 |
| 9.419e-05 | -9.27 | AICDA (activation induced cytidine deaminase) | protein interactions | 57379 | 52 | 20 | 17029 | 2761 |
EXOSC6,PRKDC,EXOSC9,HAUS4,DAZAP2,HERPUD2,PRKACA,APP,RPA1,KPNA4,KPNA1,EXOSC7,PCNA,CTNNBL1,EIF2D,EXOSC1,RTCB,KPNA2,PGAM1,HNRNPM |
| 9.419e-05 | -9.27 | IDH3A (isocitrate dehydrogenase 3 (NAD(+)) alpha) | protein interactions | 3419 | 52 | 20 | 17029 | 2761 |
STAU1,MDH2,NFATC2,ADRB2,SDHA,CCT8,EPRS,PSMD2,RPN1,HUWE1,RAB4A,DDA1,CS,SUCLG2,ACADM,DMWD,IDH3B,TERF1,TERF2,ABCC1 |
| 9.419e-05 | -9.27 | MYL12A (myosin light chain 12A) | protein interactions | 10627 | 52 | 20 | 17029 | 2761 |
CYLD,VHL,MYH9,BRCA1,CAPZA2,ANLN,MCM2,VDAC1,EIF1B,SDHA,CDC73,PARK7,SYNCRIP,SUV39H2,PTEN,NDUFB4,MYO18A,ZNF746,IGBP1,CDKN2A |
| 9.420e-05 | -9.27 | GO_CHROMATIN_BINDING | MSigDB lists | GO_CHROMATIN_BINDING | 418 | 92 | 17377 | 2626 |
MBD1,ASH1L,DNMT3A,H2AFZ,SUZ12,SMARCA4,SIRT2,ORC1,PCNA,MTA1,NOC2L,NUP153,ATF2,MCMBP,SMARCE1,DNMT1,RNF169,SP3,BRD4,HMGN4,GABPA,WBP2,WDR82,NFATC2,BRCA1,PBRM1,MBD3,TRIM28,CHAF1A,TAF2,PAF1,HHEX,SMAD2,BRD2,SAFB,BAZ1B,ACTB,NCOA1,H3F3A,BEND6,SMAD4,CBX4,HDAC2,SSRP1,POLQ,SLC30A9,DNAJC2,MUM1,MECP2,CENPF,PRKAA1,CTCF,MEF2A,TOP2B,HMGN3,EZH1,FOXO3,TTF1,SMC3,HDAC7,MCM5,MBD2,H2AFY,CITED2,TNRC18,STAT3,NCOA2,MSH6,HP1BP3,HMGN1,KAT2A,HMGN5,CIC,ZMYND11,MTA2,LDB1,ARID1A,ELK1,MEN1,HMGN2,UPF1,ATAD2,POLE,RBMX,CDCA5,NUP62,CABIN1,RUVBL2,MBD6,RBPJ,RBBP4,SMARCD1 |
| 9.435e-05 | -9.27 | ACEVEDO_NORMAL_TISSUE_ADJACENT_TO_LIVER_TUMOR_UP | MSigDB lists | ACEVEDO_NORMAL_TISSUE_ADJACENT_TO_LIVER_TUMOR_UP | 156 | 42 | 17377 | 2626 |
WSB2,PNISR,GMFG,TRIP12,GORASP1,SUMO2,ACTR3,GADD45G,EIF2AK4,RGS2,SCYL2,CHD1,CHKA,HNRNPA2B1,AHCTF1,SAR1A,ARPC5,RBM34,SEPT11,RPN2,PTGES3,MTPN,CCAR1,GTF3C6,ELOVL5,HMGN4,LAP3,EDEM2,RPL27A,EIF3A,HLA-B,HHEX,PON2,UAP1,HNRNPH3,MYO18A,RPLP1,TBPL1,UQCRH,FKBP5,IGBP1,HDAC2 |
| 9.436e-05 | -9.27 | Amino Sugar Metabolism | SMPDB pathways | SMP00045 | 17 | 10 | 992 | 167 |
CMAS,UAP1,GNPNAT1,GNPDA1,GNE,NANS,AMDHD2,SLC17A5,NANP,HEXA |
| 9.436e-05 | -9.27 | G(M2)-Gangliosidosis: Variant B- Tay-sachs disease | SMPDB pathways | SMP00534 | 17 | 10 | 992 | 167 |
CMAS,UAP1,GNPNAT1,GNPDA1,GNE,NANS,AMDHD2,SLC17A5,NANP,HEXA |
| 9.436e-05 | -9.27 | Tay-Sachs Disease | SMPDB pathways | SMP00390 | 17 | 10 | 992 | 167 |
CMAS,UAP1,GNPNAT1,GNPDA1,GNE,NANS,AMDHD2,SLC17A5,NANP,HEXA |
| 9.436e-05 | -9.27 | Sialuria or French Type Sialuria | SMPDB pathways | SMP00216 | 17 | 10 | 992 | 167 |
CMAS,UAP1,GNPNAT1,GNPDA1,GNE,NANS,AMDHD2,SLC17A5,NANP,HEXA |
| 9.436e-05 | -9.27 | Sialuria or French Type Sialuria | SMPDB pathways | SMP00217 | 17 | 10 | 992 | 167 |
CMAS,UAP1,GNPNAT1,GNPDA1,GNE,NANS,AMDHD2,SLC17A5,NANP,HEXA |
| 9.436e-05 | -9.27 | Salla Disease/Infantile Sialic Acid Storage Disease | SMPDB pathways | SMP00240 | 17 | 10 | 992 | 167 |
CMAS,UAP1,GNPNAT1,GNPDA1,GNE,NANS,AMDHD2,SLC17A5,NANP,HEXA |
| 9.444e-05 | -9.27 | GRESHOCK_CANCER_COPY_NUMBER_UP | MSigDB lists | GRESHOCK_CANCER_COPY_NUMBER_UP | 310 | 72 | 17377 | 2626 |
TCF12,FGFR1OP,CYLD,TSC2,NF1,SUZ12,PMS2,MYH9,KTN1,EXT2,ABL2,JAZF1,ETV6,TCEA1,TFG,RBM15,ABI1,POU2AF1,NRAS,BRD4,SEPT9,BIRC3,AKT2,GOPC,VHL,BRCA1,FANCE,CBFB,ERC1,STK11,CHEK2,SMAD4,EWSR1,NACA,TCF3,PCSK7,CHIC2,THRAP3,BLM,IL21R,FOXO3,TFRC,RPN1,FGFR3,RB1,IRF4,PTEN,ATIC,XPA,MSH2,PTPN11,BCL2,AFF1,SS18L1,MSH6,NCOA2,ARHGEF12,KRAS,MEN1,KLF6,PICALM,TFEB,FAS,GNAS,SDHB,TSC1,PCM1,CCDC6,PML,SRSF3,HRAS,CDKN2A |
| 9.465e-05 | -9.27 | AMUNDSON_RESPONSE_TO_ARSENITE | MSigDB lists | AMUNDSON_RESPONSE_TO_ARSENITE | 211 | 53 | 17377 | 2626 |
HNRNPAB,ST13,CHERP,TSC22D3,TAP1,LAMTOR3,DAZAP2,LYN,FOXO3,PRNP,EIF2S2,KDM2A,SLC1A4,IARS,AHSA1,IL6ST,TANK,FJX1,PDS5B,ATP6V0D1,ATP6V1G1,SRPK2,ADAM17,RAD51AP1,ATP2C1,TOP3A,ATP6V0A1,RIT1,DNAJA1,FXR1,ANLN,ZFAND5,CCT8,NEU1,AKAP1,TSC1,PFDN5,HSPA4,ETS2,TFE3,TIMM17A,HPS5,STAT6,ARNTL,CEBPG,OGT,SIAH2,CTSA,ATP6V1C1,RPS6KC1,HEXA,ATP6V0E1,N4BP2L2 |
| 9.491e-05 | -9.26 | USP15 (ubiquitin specific peptidase 15) | protein interactions | 9958 | 188 | 51 | 17029 | 2761 |
DDX58,USP7,UBE2E2,CYLD,UGP2,PHB2,IVNS1ABP,ANK3,BRAP,ATG2B,SPDL1,STAM,BIRC2,LMNA,FERMT3,WWP2,MDM2,SNUPN,SMC3,SHC1,HUWE1,JOSD1,COPS7B,RNF26,TERF2,CSTF1,PLK1,CCDC57,BIRC3,CUL3,ADSL,LSM8,USP10,NUSAP1,PRPF3,MCM2,SOX4,PSMB9,CDK11A,USP21,CAND1,KEAP1,SMAD2,LSM6,AXIN1,USP20,PRPF4,SMAD1,USP11,SMURF1,SMAD4 |
| 9.491e-05 | -9.26 | PSMC3 (proteasome 26S subunit, ATPase 3) | protein interactions | 5702 | 188 | 51 | 17029 | 2761 |
CCDC93,CYLD,PHB2,CXXC1,FLYWCH2,UBXN1,PMS2,POMP,EIF2AK4,UBE2I,PSMD9,EPM2A,UBLCP1,GTF2F1,RAD23A,RPN1,PSMD2,MDM2,PSMD1,PSMA6,HUWE1,UCHL5,ARHGEF1,CRY2,MAVS,ECD,CDC5L,TXNL1,RNASEH2C,PSMA8,VHL,PSMB7,PSMA1,ATXN1,BRCA1,PSMB9,RFC2,PSMB3,PSMC4,MBIP,FBXO28,PSMD8,PSMD3,EIF2D,STAT1,FAM83D,MAP3K5,PSMC1,TSEN15,PARD3,CDKN2A |
| 9.559e-05 | -9.26 | REACTOME_DOWNSTREAM_SIGNAL_TRANSDUCTION | MSigDB lists | REACTOME_DOWNSTREAM_SIGNAL_TRANSDUCTION | 90 | 28 | 17377 | 2626 |
PDPK1,NRAS,TSC2,NCK1,AKT2,RAF1,PRKAR1B,KRAS,AKT1S1,PRKACA,FOXO3,MAP2K2,MAPK3,CRKL,CALM2,MDM2,PTEN,STAT6,PIK3R2,ADCY9,STAT1,CDKN1B,CREB1,STAT3,MAPK1,HRAS,ADCY7,MLST8 |
| 9.559e-05 | -9.26 | GO_ESTABLISHMENT_OF_LOCALIZATION_BY_MOVEMENT_ALONG_MICROTUBULE | MSigDB lists | GO_ESTABLISHMENT_OF_LOCALIZATION_BY_MOVEMENT_ALONG_MICROTUBULE | 90 | 28 | 17377 | 2626 |
KIF3B,DYNLL1,AP3M2,KIF23,RAB6A,WDR81,BICD2,RAB1A,RHOT1,AP3S1,IFT27,RHOT2,APP,BBS12,TMEM201,KIF5B,RAB21,PCM1,CDC42,AP3S2,LRPPRC,SSNA1,KIFAP3,CLN3,NDE1,IFT46,DCTN1,SNAPIN |
| 9.574e-05 | -9.25 | GSE12001_MIR223_KO_VS_WT_NEUTROPHIL_UP | MSigDB lists | GSE12001_MIR223_KO_VS_WT_NEUTROPHIL_UP | 161 | 43 | 17377 | 2626 |
UNK,DHPS,NUP54,NKRF,HAUS2,RRN3,PA2G4,PDCD10,CTNNBL1,XRCC2,ZDHHC13,PARL,SUCLG2,AHCY,GEMIN4,CREB1,EIF5,AHCYL1,RBM15,STAT3,TDP1,CCT2,AATF,GUK1,PGS1,TYW1,BOLA1,SLC25A22,BMS1,UTP3,SHCBP1,BBS12,RHBDF2,TWISTNB,PHF6,RBM25,TFDP1,NFIL3,PTAR1,FAM122A,SLC25A19,ANP32E,RNF114 |
| 9.574e-05 | -9.25 | MORF_FANCG | MSigDB lists | MORF_FANCG | 161 | 43 | 17377 | 2626 |
NUP188,PRKCSH,SLC2A1,AGPAT1,KLHL18,CSNK2A1,CDK13,NKRF,MYO9B,PMF1,PARN,SRRT,RPA2,TFAP4,PPIL2,MEA1,BCL2,CPSF4,KDM3B,TSTA3,ZNF500,LDB1,MKI67,BMS1,PKMYT1,MTX1,PCGF1,CCNF,POLR2A,MFN2,TAF2,SEC31A,GALNT2,CHD3,PSMD3,PML,NUP62,TCOF1,WDR62,PPP5C,B4GALT3,DDB1,NUDT3 |
| 9.622e-05 | -9.25 | ATP-dependent RNA helicase activity | molecular function | GO:0004004 | 67 | 23 | 17224 | 2647 |
DDX28,DDX47,SNRNP200,DDX24,DHX29,HELB,YTHDC2,DHX9,DHX8,DDX20,DDX39A,DHX15,DHX57,DDX23,DDX17,DDX56,UPF1,EIF4A3,DHX16,DDX31,DDX5,DDX42,DDX52 |
| 9.627e-05 | -9.25 | KAYO_AGING_MUSCLE_DN | MSigDB lists | KAYO_AGING_MUSCLE_DN | 113 | 33 | 17377 | 2626 |
NDUFV2,UGP2,NIPA2,SNRPD3,BLM,MAPK14,PABPC4,PSMA6,EXOSC7,ALDH9A1,POLR2G,ELL2,ERF,HMGN4,TOP3A,VDAC2,RTF1,NEU1,KRIT1,MAN2A2,SDHB,PON2,CDC16,QARS,PARG,MAPK6,COX8A,IMPDH1,MDH1,UQCRH,PPP5C,IFI16,BYSL |
| 9.639e-05 | -9.25 | CHORDC1 (cysteine and histidine rich domain containing 1) | protein interactions | 26973 | 72 | 25 | 17029 | 2761 |
BCCIP,SARNP,REPS2,CDCA3,UBE2V1,EIF2A,SEPT7,MCM2,EDRF1,SCYL2,SH3GLB1,CDK5,CAPN2,SUB1,MRPL55,NSRP1,AHSA1,IARS2,SEPT11,FKBP5,TTC4,TCEA1,PPP5C,FUBP1,CDC37 |
| 9.639e-05 | -9.25 | PDHB (pyruvate dehydrogenase E1 beta subunit) | protein interactions | 5162 | 72 | 25 | 17029 | 2761 |
RMND5A,COX15,PPP3CA,STAU1,PPT1,CUL3,PPP3CB,ADRB2,OGDH,VDAC1,ARMC8,GNB2,PDHX,PARK7,RPSA,CAND1,PDK2,HUWE1,ZNF746,ITGB1,PPP3R1,COX5A,PCYT2,EIF5,CFAP20 |
| 9.644e-05 | -9.25 | EEF1G (eukaryotic translation elongation factor 1 gamma) | protein interactions | 1937 | 174 | 48 | 17029 | 2761 |
KARS,PRPF38B,CYLD,SUMO2,NACA,CDK2AP2,GADD45G,KLHL18,CUL1,ARF1,SDHA,KTN1,PARK7,CDC73,WWP2,CDC42,UCHL5,TARDBP,PABPC1,NUP85,EEF1D,STAU1,LARS,HARS,STRIP1,RPL38,CUL3,RPL8,EXOSC9,RANGAP1,BRCA1,ADRB2,VDAC1,MCM2,ECH1,ISG15,CAND1,EPRS,HNRNPH3,PLGRKT,CHMP4B,FUS,PLOD3,CDK2,SMURF1,IPO4,NUDT3,SNAPIN |
| 9.730e-05 | -9.24 | CAIRO_HEPATOBLASTOMA_UP | MSigDB lists | CAIRO_HEPATOBLASTOMA_UP | 196 | 50 | 17377 | 2626 |
ANKRD27,TOMM20,PLXNC1,PPP1R2,TOR3A,MAGED1,VPS45,TIA1,SMARCA4,RACGAP1,RCOR3,SAC3D1,SLC25A36,DLG5,ASAP2,SLC1A4,RBM34,MRPS27,CS,PDCD2,MAVS,SLC26A2,MINPP1,ZNF189,SOCS5,FDFT1,KDM3B,SP3,MLEC,HMGN4,TACC1,TSPYL4,NSDHL,MAP4K4,SEPT8,GORASP2,LRRC1,CDC23,SOX4,FXR1,MTR,RPA1,MAGED2,MAP3K4,NAP1L1,ACLY,RNF38,PDXK,RPS6KC1,HDAC2 |
| 9.754e-05 | -9.24 | GSE11864_UNTREATED_VS_CSF1_IFNG_IN_MAC_UP | MSigDB lists | GSE11864_UNTREATED_VS_CSF1_IFNG_IN_MAC_UP | 171 | 45 | 17377 | 2626 |
WASF2,KCTD7,UBL3,ZNF296,PDCD6IP,REPS2,TRIM11,TRAK1,DLGAP4,MYH9,SLC12A9,SLC25A36,RAP1A,NT5DC1,GLTP,JOSD1,TCEA1,RNF135,SMARCE1,RHBDD2,PHF10,ELOVL5,PTPN18,MAPKAPK3,TSPYL4,NET1,PSPC1,NARF,RPL6,MEF2D,TAZ,RPS9,ZDHHC3,XRCC5,HHEX,SERTAD2,VPS26B,QARS,ERGIC3,ZDHHC7,IMPDH1,SLAIN1,ZNF598,SAT2,RNF139 |
| 9.757e-05 | -9.23 | PLS3 (plastin 3) | protein interactions | 5358 | 56 | 21 | 17029 | 2761 |
UNK,STAU1,EWSR1,ANXA6,HARS,TKT,EZR,NANS,SND1,APP,ISG15,CLNS1A,HLA-B,PA2G4,SHC1,ANXA5,TAGLN2,GPI,TALDO1,PPA1,MYO5A |
| 9.757e-05 | -9.23 | SP100 (SP100 nuclear antigen) | protein interactions | 6672 | 56 | 21 | 17029 | 2761 |
LZTR1,DNMT3A,SUMO2,NUF2,UBE2I,ETS1,VPS25,CREM,CBX3,TERF2IP,SP100,L3MBTL3,HIPK2,PML,LTN1,AHCYL1,IGBP1,SENP1,TERF1,IFI16,TERF2 |
| 9.757e-05 | -9.23 | TBL3 (transducin beta like 3) | protein interactions | 10607 | 56 | 21 | 17029 | 2761 |
NIFK,AATF,DDX24,UTP15,GTPBP4,TGOLN2,AURKB,BRCA1,RBM4,USP36,KRR1,DDX56,ZNF746,EXOSC1,NOC2L,RP2,POLR1B,FBL,USP11,FTSJ3,IFI16 |
| 9.766e-05 | -9.23 | SMARCA2 (SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2) | protein interactions | 6595 | 106 | 33 | 17029 | 2761 |
ADD1,MECP2,SMARCA4,TOP2B,NSD3,ARID1B,RAP1A,MDM2,SMC3,BANF1,SEPT11,MCPH1,SMARCE1,SAP30,CDC5L,PHF10,ZMYND11,ARID1A,BRCA1,MBD3,POLR2A,CHD3,PITX1,H2AFX,BCL7C,STAT1,KHSRP,RBBP4,TAF6,ZMAT3,HDAC2,FUBP1,SMARCD1 |
| 9.782e-05 | -9.23 | GSE6092_UNSTIM_VS_IFNG_STIM_ENDOTHELIAL_CELL_UP | MSigDB lists | GSE6092_UNSTIM_VS_IFNG_STIM_ENDOTHELIAL_CELL_UP | 191 | 49 | 17377 | 2626 |
INTS2,CTU2,COMMD10,TMED7,FGFR1OP,NDUFS1,ZNF768,PIGQ,BCL2L1,ARF1,DCUN1D4,UBE2I,CD320,SSR1,USP5,UBXN2A,ATP2A2,NEK6,CENPJ,RNASEK,DDA1,SEPT11,STAT3,PPIF,PLK3,SHOC2,USO1,AGGF1,ABHD11,SYVN1,OGDH,RHOT1,GFER,HSPA1B,C1orf122,TFEB,UBTF,HSPA4,IDE,KPNA1,CCDC86,RBMX,STX18,FKBP5,PREPL,BTBD10,CBX4,GPATCH4,PFKP |
| 9.782e-05 | -9.23 | GSE7548_NAIVE_VS_DAY7_PCC_IMMUNIZATION_CD4_TCELL_UP | MSigDB lists | GSE7548_NAIVE_VS_DAY7_PCC_IMMUNIZATION_CD4_TCELL_UP | 191 | 49 | 17377 | 2626 |
SEPHS2,KCTD7,GLT8D1,PNISR,PHB2,UBN1,TMEM97,LETMD1,MXD4,S1PR2,PARN,FOXO3,STAM,PDXDC1,MBD4,SLC25A36,OIP5,NFATC3,PTEN,HADHB,MDFIC,GEMIN4,PIKFYVE,LPCAT1,OGG1,CSTF1,PPIF,TXNL1,KAT2A,ATG9A,NSDHL,KIAA0930,FAM50B,MPG,RHOB,RPA1,PRIM1,HMGN2,GNA12,SERTAD2,PDCD6,OSBPL8,LUC7L3,OAZ2,ARAP1,COPS6,ZMIZ1,ARRB2,COIL |
| 9.782e-05 | -9.23 | GSE37533_PPARG1_FOXP3_VS_PPARG2_FOXP3_TRANSDUCED_CD4_TCELL_PIOGLITAZONE_TREATED_DN | MSigDB lists | GSE37533_PPARG1_FOXP3_VS_PPARG2_FOXP3_TRANSDUCED_CD4_TCELL_PIOGLITAZONE_TREATED_DN | 191 | 49 | 17377 | 2626 |
DDX58,GCLM,PKP4,CYLD,PARP12,NF1,HLA-E,UBR2,TAP1,ARID5A,BTN3A1,DNAJB1,ZNF267,ATP6V1B2,HLA-A,GOLM1,SP100,ATP2A2,TANK,AKAP8,CLCN6,TAP2,FBXL7,AFF1,SGCB,SCYL3,CTDSP2,PPA1,TRIM14,ACSL5,BAK1,CYTH1,TRAFD1,BAZ2A,LAP3,DNAJA1,OGFR,EDEM2,PSMB9,ISG15,DDX23,HLA-B,STAT1,PML,SIAH2,FKBP5,APOL2,ZC3HAV1,RNF114 |
| 9.782e-05 | -9.23 | GSE43955_1H_VS_20H_ACT_CD4_TCELL_WITH_TGFB_IL6_UP | MSigDB lists | GSE43955_1H_VS_20H_ACT_CD4_TCELL_WITH_TGFB_IL6_UP | 191 | 49 | 17377 | 2626 |
IER2,AGTRAP,PHB2,CTCF,GMCL1,HAUS4,MAN2B1,ARF1,PARN,RAD23A,CDKN2C,ATP6V0B,AKAP8,ARHGEF1,ABCD1,RPL19,NDUFA3,FGFR1OP2,KCNAB2,PCBP2,CSTF1,FYTTD1,TGFB1,EIF3L,POLR2I,GUK1,EMB,SELPLG,FBXO9,EIF2AK1,PACS1,ARHGDIB,DNAJA1,TXNL4A,COMMD4,XRCC5,CHCHD3,FBXO21,MKNK1,PPP2R5A,ACOX1,STAT6,CDCA5,PRPS2,OAZ2,PPP5C,LTA4H,IPO4,FAF1 |
| 9.782e-05 | -9.23 | GSE360_L_MAJOR_VS_T_GONDII_MAC_DN | MSigDB lists | GSE360_L_MAJOR_VS_T_GONDII_MAC_DN | 191 | 49 | 17377 | 2626 |
SRM,NCOR2,ATXN3,H2AFZ,RAE1,TCF3,SLC2A1,MED13L,ARFIP2,OAT,CCNB1,FAM8A1,HDDC2,KIFC1,RPA2,TFAP4,FLAD1,HOMER1,PCNA,EXOSC7,INPP5A,PIN1,MSH2,EI24,CYC1,ERI3,IMPA2,MSH6,CPNE1,HARS,MRPL12,ILF3,SLBP,SRSF5,MCM2,CYFIP2,SF3A2,CHAF1A,MFN2,ADSS,SDHB,ALG3,EPRS,UPF1,HNRNPR,PIEZO1,IDH3B,HRAS,BYSL |
| 9.782e-05 | -9.23 | GSE27786_CD4_TCELL_VS_NKTCELL_DN | MSigDB lists | GSE27786_CD4_TCELL_VS_NKTCELL_DN | 191 | 49 | 17377 | 2626 |
POU3F2,GALK1,PKP4,MAPRE1,NOP2,CDT1,MEF2A,SECISBP2,AKT1S1,BLM,IFT27,MFSD10,NUP205,LRRC14,PCYOX1L,SLC25A36,TMEM69,NUP210,CENPJ,RRBP1,EI24,H2AFY,OSTF1,MAVS,POLR1B,ALDH18A1,UBE2M,PABPC1,CARM1,RNASEH2C,LAP3,RAD51AP1,METTL5,MAP7D1,ZP3,PDE3B,NCDN,GNAS,KIF2A,WAS,DDOST,SCAP,PPM1G,COX8A,EXOC4,PPP3R1,PDLIM5,COIL,SLC25A39 |
| 9.782e-05 | -9.23 | GSE17812_WT_VS_THPOK_KO_MEMORY_CD8_TCELL_DN | MSigDB lists | GSE17812_WT_VS_THPOK_KO_MEMORY_CD8_TCELL_DN | 191 | 49 | 17377 | 2626 |
CHTF18,WDR13,CENPF,TPX2,RRAGC,TMED3,B4GALT4,STMN1,APP,MFSD10,SPAG5,CHKA,DECR1,ASAP2,CCNA2,TNFAIP8,RRBP1,BRI3,MAP3K14,RNF135,TMEM8A,MOB1A,WDR41,NAGPA,ADAM17,MAPRE2,TK1,TCTEX1D2,BIRC3,ELL2,ERLIN1,TSPAN31,SLBP,AURKB,SMC2,CCNF,PRKRA,RFC2,NAP1L1,ATAD2,ELMO1,TFDP1,CEP55,NRM,ATF6,ANP32E,RBPJ,USP11,SLC25A39 |
| 9.800e-05 | -9.23 | GSE3720_UNSTIM_VS_PMA_STIM_VD2_GAMMADELTA_TCELL_DN | MSigDB lists | GSE3720_UNSTIM_VS_PMA_STIM_VD2_GAMMADELTA_TCELL_DN | 176 | 46 | 17377 | 2626 |
PTMS,AGTRAP,FOXM1,FAM129A,C5orf30,KLF13,KIF23,RACGAP1,SIRT2,DNAJB1,TWF2,LYN,GNB2,TUBGCP2,SPAG5,EBP,CAPN2,GOLM1,RAB8A,SAR1A,MCM5,RAB4A,SLC27A4,H2AFY,AHCYL1,C12orf75,DNMT1,ARL5A,KCNAB2,ACSL5,DDX28,SEPT8,CKAP2L,NUSAP1,ESYT1,BUD13,CCNF,KRTCAP2,MCM2,PRIM1,PWWP2B,UAP1,BIRC5,NFIL3,NLRC5,IDH3B |
| 9.800e-05 | -9.23 | GSE25123_ROSIGLITAZONE_VS_IL4_AND_ROSIGLITAZONE_STIM_PPARG_KO_MACROPHAGE_DAY10_UP | MSigDB lists | GSE25123_ROSIGLITAZONE_VS_IL4_AND_ROSIGLITAZONE_STIM_PPARG_KO_MACROPHAGE_DAY10_UP | 176 | 46 | 17377 | 2626 |
NDUFV2,GCLM,MRPL42,MRPS26,CDCA3,C19orf25,STARD7,OAT,SLC20A1,MRPL19,SUV39H2,CWC27,LRRC8D,BANF1,MSH2,ZBTB22,KNTC1,CENPM,MRPL48,RNASEH2A,NUDC,WDR41,SNX8,EIF3L,IDH3A,PCGF6,DDX20,ADSL,NUP155,EXOSC9,KRAS,PPWD1,BRCA1,SEPT7,MTHFD2,HSPBP1,POLE,QARS,DBI,AP1S1,RBMS1,RUVBL2,SASS6,IGBP1,NIPA1,SSRP1 |
| 9.800e-05 | -9.23 | GSE3982_CTRL_VS_IGE_STIM_MAST_CELL_DN | MSigDB lists | GSE3982_CTRL_VS_IGE_STIM_MAST_CELL_DN | 176 | 46 | 17377 | 2626 |
MIF,KLHL18,ARFIP2,SLC4A2,ADPGK,MAN2B1,BCL2L1,DCUN1D4,SLC25A37,PSMA6,NVL,KIF22,AFF1,MINPP1,MCMBP,EEF1D,GPX4,MAPRE2,MKLN1,CSRP1,ZNF500,ZFAND5,MAT2A,RHEB,NEU1,FAS,FBXO21,TPD52L2,KPNA1,ATP1A1,SERF2,SPATA2,TMED10,PQBP1,CANT1,MLYCD,PPP1R11,AP1S1,FKBP5,DDX5,GPI,RUFY3,SMURF1,PDCD11,AP2S1,DDX52 |
| 9.800e-05 | -9.23 | KEGG_ENDOCYTOSIS | MSigDB lists | KEGG_ENDOCYTOSIS | 176 | 46 | 17377 | 2626 |
CHMP2A,SMAP1,PDCD6IP,RAB11B,HLA-E,VPS45,ACAP1,EPN1,RUFY1,RAB11A,GIT2,STAM,VPS25,TFRC,HLA-A,PIP5K1C,FGFR3,ASAP2,MDM2,CDC42,RAB4A,DNM2,AP2B1,PIKFYVE,CLTB,F2R,ADRB2,CHMP2B,RAB5B,RAB22A,SH3GLB1,SMAP2,HSPA1B,HLA-B,HGS,CHMP4A,ARAP1,SH3GLB2,CHMP4B,VPS4A,EHD4,SMURF1,ARRB2,AP2S1,HRAS,PARD3 |
| 9.812e-05 | -9.23 | GSE1432_1H_VS_6H_IFNG_MICROGLIA_UP | MSigDB lists | GSE1432_1H_VS_6H_IFNG_MICROGLIA_UP | 186 | 48 | 17377 | 2626 |
CYTIP,HECA,MDH2,SRSF6,BABAM1,GADD45G,TRAK1,TKT,CERK,COX4I1,TBC1D13,RGS2,MYL6B,PRPF18,FBXO5,SLC25A36,SNRNP25,ATIC,BDH1,FUT8,PARL,SS18L1,LPCAT1,OGG1,KCNAB2,SPSB3,AMPD2,CLCN3,NET1,MRS2,RABIF,RCOR1,UBE4B,NDRG3,PDE3B,STK17B,RHOB,NMT2,ABHD5,ADSS,MTMR3,PFDN5,SPATA2,LRPPRC,CCNB2,RTN3,ZMAT3,OAZ1 |
| 9.812e-05 | -9.23 | GSE27786_LIN_NEG_VS_CD4_TCELL_DN | MSigDB lists | GSE27786_LIN_NEG_VS_CD4_TCELL_DN | 186 | 48 | 17377 | 2626 |
GGNBP2,LIME1,TAP1,ARID5A,MED13L,CHIC2,CHCHD2,EZH1,EIF1B,SLC20A1,IL21R,ANKIB1,GIT2,RRP36,CFLAR,DDRGK1,EBP,SF3B2,TMEM179B,HUWE1,NT5DC1,MBD2,PPP1R12C,PPCDC,ARL6IP1,HADHB,AKR1B1,PIK3IP1,ATF2,NSUN4,KCNAB2,TIMP2,NFATC2,RIT1,AZI2,HERPUD2,MARK2,MTMR3,SMAD2,JAK1,RAB24,AXIN1,NLRC5,IDH3B,BRD9,RPS26,SMAD4,HIGD2A |
| 9.812e-05 | -9.23 | GSE29618_PRE_VS_DAY7_POST_TIV_FLU_VACCINE_PDC_DN | MSigDB lists | GSE29618_PRE_VS_DAY7_POST_TIV_FLU_VACCINE_PDC_DN | 186 | 48 | 17377 | 2626 |
SART1,COPA,PRKCSH,MRPS15,NACA,NENF,IRF3,UBE4A,GGPS1,FBXO22,GTF2F1,RAD23A,FBRS,CLUAP1,RAB8A,BANF1,NOC2L,ANP32A,FEM1B,TNPO2,AP2B1,RPL19,GNAI2,TGFB1,SGCE,BRD4,PTPN18,RPL35,TIMP2,OSBP2,NCK1,EID1,SIGMAR1,OGDH,MPG,SF3A2,RHOB,EIF3A,RPL37,KIF2A,KPNA1,SMAD2,RBMX,GADD45B,ATXN2L,TFDP2,YWHAH,ZMAT3 |
| 9.812e-05 | -9.23 | GSE19888_ADENOSINE_A3R_INH_PRETREAT_AND_ACT_BY_A3R_VS_A3R_INH_AND_TCELL_MEMBRANES_ACT_MAST_CELL_DN | MSigDB lists | GSE19888_ADENOSINE_A3R_INH_PRETREAT_AND_ACT_BY_A3R_VS_A3R_INH_AND_TCELL_MEMBRANES_ACT_MAST_CELL_DN | 186 | 48 | 17377 | 2626 |
SLC30A9,PRKAB1,FEZ2,CKLF,CASP6,MANBA,SRSF6,MUM1,ANKH,TOR1AIP1,CTCF,MYO9B,DNAJB1,CRLF3,ELMOD2,CMTM6,BIRC2,GIT2,FBRS,RB1,NRF1,RAB8A,GPATCH1,RNF135,ARID4A,NCOA2,PLK1,NRAS,FOXK1,TSPYL4,OXR1,MIER1,DDX20,SYVN1,DHX15,ANKRD46,BTBD1,BRMS1,MID1IP1,CLK3,RAB24,ARNTL,APPL2,RNF38,RBMS1,RGL1,FAU,C11orf1 |
| 9.812e-05 | -9.23 | GSE2770_IL12_VS_IL4_TREATED_ACT_CD4_TCELL_6H_DN | MSigDB lists | GSE2770_IL12_VS_IL4_TREATED_ACT_CD4_TCELL_6H_DN | 186 | 48 | 17377 | 2626 |
WSB2,TMEM184B,UBR2,MUM1,DNAJC24,CUL1,SNN,MAPK14,RCOR3,LCLAT1,ETS1,PITHD1,KCMF1,MYEF2,MCTS1,SEC11A,GSTK1,VASP,CLIC4,ZNHIT6,PPP6C,LDLRAD3,MRPL32,TIMM50,SMC4,SNX8,PPP3CA,DDX28,GTF3C6,NRAS,POLR2I,CIRBP,TUFM,EMP3,NDUFA7,THNSL1,PRKRA,KRIT1,NECAP2,EIF3K,STK38,TCOF1,AKNA,CDK2,C11orf1,RTN3,NRBP1,ESYT2 |
| 9.812e-05 | -9.23 | GSE360_L_MAJOR_VS_M_TUBERCULOSIS_DC_UP | MSigDB lists | GSE360_L_MAJOR_VS_M_TUBERCULOSIS_DC_UP | 186 | 48 | 17377 | 2626 |
CTDP1,PTMS,MRPL9,MDH2,ABCC10,TCF3,GADD45G,ASAH1,SMARCA4,COX4I1,TMED3,AP1B1,PCBP1,FOXO3,CHD1,CNOT3,EBP,MDM2,BDH1,H2AFY,CARM1,SLC25A1,CDC5L,VPS13B,PPIF,NIPAL3,PLK3,TK1,TIMP2,ATG9A,KIAA0040,FRAT2,DIDO1,KCNQ1,PLEC,H2AFV,MAP2K2,CLNS1A,AKAP1,GPS2,TFE3,RBMS1,COX5A,UQCRH,HMGB2,RRS1,USF2,IGBP1 |
| 9.812e-05 | -9.23 | GSE6674_PL2_3_VS_ANTI_IGM_AND_CPG_STIM_BCELL_DN | MSigDB lists | GSE6674_PL2_3_VS_ANTI_IGM_AND_CPG_STIM_BCELL_DN | 186 | 48 | 17377 | 2626 |
MIF,CCNC,TMEM184B,CAST,ARID5A,DLGAP4,LETMD1,B4GALT1,ZNRF3,DUSP22,RAB11A,HLA-A,RGS1,MAN1A1,PRNP,RBM17,CAPN2,IRF4,RABGAP1L,MBD2,MDFIC,AFF1,TP53BP2,SMARCE1,IFT46,DRAM2,PTPRK,RYBP,SAP30,ANKLE2,ZNF524,ZDHHC18,SEPT9,GALC,LYRM1,MIER1,WDR82,USP22,EDEM2,KDM3A,PHF6,SH3GLB1,MTMR3,SCARB2,FBXO28,HIPK2,DNAJC30,FAF1 |
| 9.812e-05 | -9.23 | GSE13411_NAIVE_VS_IGM_MEMORY_BCELL_DN | MSigDB lists | GSE13411_NAIVE_VS_IGM_MEMORY_BCELL_DN | 186 | 48 | 17377 | 2626 |
NSMCE4A,MDH2,CDT1,RAC1,COPE,ZFYVE21,RUFY1,EDC3,PIN1,BANF1,FUT8,NAP1L4,TALDO1,ATP6V0D1,PABPC1,SLC25A1,TERF2,ABCC1,LDHB,NAGPA,VOPP1,BAK1,ORAI2,PTPN18,AKT2,MRPL12,LDHA,ATXN1,EIF2AK1,VDAC1,KLF6,PEF1,EIF3G,ISG15,PSMC4,YIF1A,TPD52L2,KEAP1,RBM47,QARS,GOLGA8A,TFDP1,PPM1G,DCAF11,RBMS1,GALNT10,ZMIZ1,PGAM1 |
| 9.812e-05 | -9.23 | GSE27786_LSK_VS_ERYTHROBLAST_UP | MSigDB lists | GSE27786_LSK_VS_ERYTHROBLAST_UP | 186 | 48 | 17377 | 2626 |
NDUFV2,ANKRD13D,TM9SF4,DCAF15,TKT,POMP,GLRX3,ZNF518A,SDHA,HMG20A,RRP36,RNF103,NDUFS4,EBP,WRNIP1,SLC25A36,PDXP,GOT2,PHF14,ZNF260,MECR,EI24,C12orf75,TSHZ1,FAM172A,SIGMAR1,VHL,IDH3A,NOL8,SCFD2,TUFM,SSR2,STX16,GUF1,ARSK,BTBD1,DUS3L,PDLIM1,CHD3,CORO1C,MRPL27,DBI,SEL1L,IARS2,SCARB1,SSSCA1,RHEBL1,ZBTB24 |
| 9.818e-05 | -9.23 | GSE17721_CTRL_VS_PAM3CSK4_4H_BMDC_UP | MSigDB lists | GSE17721_CTRL_VS_PAM3CSK4_4H_BMDC_UP | 181 | 47 | 17377 | 2626 |
C19orf53,TRIM11,MRPS26,NDUFA4,RACGAP1,SLC12A9,PRKACA,STMN1,CMTM6,COPG2,CCDC28A,XPR1,C14orf119,HOMER1,RAP1A,PCNA,MBD2,CAPZA1,CORO1A,MRPL11,CNOT6L,TALDO1,HP1BP3,TDP1,RPRD1A,POLR2I,GALC,POLK,NEK7,RPL6,SEPT8,DNAJC9,ADRB2,ANLN,CLNS1A,TFEB,MTMR3,MKNK1,MRPL2,OSBPL11,NEK1,MFAP1,CNOT6,ATF6,SLC25A39,AAAS,FAF1 |
| 9.818e-05 | -9.23 | GSE15330_HSC_VS_GRANULOCYTE_MONOCYTE_PROGENITOR_UP | MSigDB lists | GSE15330_HSC_VS_GRANULOCYTE_MONOCYTE_PROGENITOR_UP | 181 | 47 | 17377 | 2626 |
SRM,TCF12,UBL3,CTDP1,DNAJC5,ST13,KRBA1,CBLL1,IRF3,PDCD7,RGS2,C2orf49,ATP6V1B2,UBE2I,RRP36,CSDE1,VAV1,RRN3,VASP,CYB5RL,MEA1,MECR,MRPL21,TFG,PDIA6,RHBDD2,YTHDC1,PPIF,METTL1,CCT2,TRIM8,PRRC2A,ZMYM5,NSUN2,TUBGCP5,CCT8,SF3A2,TMEM184C,FBXO28,JAK1,E2F4,ARAP1,ATP6V1C1,GPATCH4,CSNK1D,FUBP1,CCDC137 |
| 9.818e-05 | -9.23 | GSE3982_BASOPHIL_VS_TH2_DN | MSigDB lists | GSE3982_BASOPHIL_VS_TH2_DN | 181 | 47 | 17377 | 2626 |
MRPL42,MRPL39,OLA1,RRM1,PXMP2,TMED3,BLM,DCUN1D4,GLRX3,TTF1,HMG20A,PARK7,SPAG5,MCTS1,CLIC4,SNUPN,IARS,LRRC8D,BANF1,PTPN11,MSH2,MAVS,GEMIN4,MRPL11,LUC7L2,MOSPD1,PPIF,EIF5A,CDC123,PPT1,SIGMAR1,ERF,TEX10,ABCF2,WDR18,HNRNPF,TOP3A,ILF3,NUSAP1,TOMM40,PSMC4,PFDN4,LSM6,E2F4,RNASEL,ESPL1,USP13 |
| 9.818e-05 | -9.23 | GSE14308_TH2_VS_NAIVE_CD4_TCELL_UP | MSigDB lists | GSE14308_TH2_VS_NAIVE_CD4_TCELL_UP | 181 | 47 | 17377 | 2626 |
CASP6,RBM8A,FLOT1,VTI1A,RRAGC,SUMF1,HMGN3,SLC29A1,PLXNA1,BCAP31,PNO1,NUP205,USP5,SRXN1,NDUFV1,PCNA,PSMD1,KIF14,C8orf59,LRRC59,ZNF800,POC5,ATP6V1G1,NASP,LONRF3,GALC,NEK7,SNRPB,METTL5,KCTD20,ANAPC2,EIF2AK1,UTP3,DCUN1D5,MEN1,CCT8,GINS4,SRSF1,OPTN,NSA2,ACAT1,FKBP5,NDUFS5,RRS1,RPS6KC1,YWHAH,SSRP1 |
| 9.842e-05 | -9.23 | RNF111 (ring finger protein 111) | protein interactions | 54778 | 68 | 24 | 17029 | 2761 |
UBE2D3,UBE2E2,TRIM8,RB1CC1,SUMO2,TPX2,CSNK2A1,UBE2V1,DCUN1D5,UBE2I,SUGP1,SMAD2,ADD3,UBE2Q2,AXIN1,TTC9C,PML,AXIN2,CREB1,MVP,LRSAM1,TRAF5,UBE2M,CGGBP1 |
| 9.868e-05 | -9.22 | APC (APC, WNT signaling pathway regulator) | protein interactions | 324 | 193 | 52 | 17029 | 2761 |
USP7,MAPRE1,PNISR,ZFP91,NUP54,STRN4,CSNK2A1,AGFG1,CSNK1A1,PRKACA,MBD4,KIF5B,ANKRD28,DST,RPA2,PCNA,PSMD1,SMC3,SIAH1,AXIN2,NUP107,AP2B1,KIFAP3,NUP153,ZRANB1,SENP1,DVL2,HTRA2,HNRNPM,EEF1D,PDLIM2,TELO2,SNRNP200,MAPRE2,VHL,ERBIN,MACF1,MARK2,SEC31A,PPP2CA,HGS,GOLGA2,PPP2R5A,CCDC6,AXIN1,BBX,KIAA1328,TRIM32,SASS6,NUP58,CSNK1D,RNF114 |
| 9.924e-05 | -9.22 | RFC2 (replication factor C subunit 2) | protein interactions | 5982 | 60 | 22 | 17029 | 2761 |
RFC3,BRD4,PRKDC,CHTF18,CHD1L,PMS2,CUL3,NFATC2,BRCA1,RPA1,CAND1,GTF2F1,RPA2,PCNA,RAD18,SETD3,EXOSC1,RTCB,USP20,PURA,IFI16,CDC5L |
| 9.924e-05 | -9.22 | KNOP1 (lysine rich nucleolar protein 1) | protein interactions | 400506 | 60 | 22 | 17029 | 2761 |
NOL12,PPAN,STAU1,RPS2,NOP2,DDX24,ZNF512,EBNA1BP2,MAK16,DHX15,CENPU,RPL36,UBTF,SYNCRIP,DGCR8,RBM34,RPF2,DDX31,RRS1,SNRNP70,FBL,FTSJ3 |
| 9.929e-05 | -9.22 | Platinum drug resistance | KEGG pathways | ko01524 | 73 | 25 | 7161 | 1149 |
PDPK1,BAK1,ERCC1,BIRC3,AKT2,XIAP,TOP2B,CYCS,BRCA1,BCL2L1,BIRC2,FADD,MAPK3,FAS,SLC31A1,MDM2,BIRC5,XPA,PIK3R2,MSH2,BCL2,MAP3K5,MAPK1,MSH6,CDKN2A |
| 9.929e-05 | -9.22 | Platinum drug resistance | KEGG pathways | hsa01524 | 73 | 25 | 7161 | 1149 |
PDPK1,BAK1,ERCC1,BIRC3,AKT2,XIAP,TOP2B,CYCS,BRCA1,BCL2L1,BIRC2,FADD,MAPK3,FAS,SLC31A1,MDM2,BIRC5,XPA,PIK3R2,MSH2,BCL2,MAP3K5,MAPK1,MSH6,CDKN2A |
| 9.945e-05 | -9.22 | SLC15A1 (solute carrier family 15 member 1) | protein interactions | 6564 | 64 | 23 | 17029 | 2761 |
INTS2,MTX3,BTAF1,SLC26A6,C19orf25,DNAAF5,PXMP2,MTX1,SLC35B2,PDXDC1,SFXN5,XPR1,RHEB,JAK1,ARF5,BDH1,PDS5B,ABCD1,KNTC1,RNASEL,APOOL,NR2F2,CHPT1 |
| 1.000e-04 | -9.21 | tRNA processing | REACTOME pathways | R-HSA-72306 | 109 | 34 | 10287 | 1696 |
CTU2,NDC1,TP53RK,NUP188,RAE1,TRMT6,LAGE3,NUP54,C2orf49,NUP205,GTPBP3,NUP210,TRMU,POP7,NUP107,RTCB,DUS2,NUP153,CPSF4,NUP85,SEH1L,METTL1,RPP25,NSUN2,TYW1,NUP155,EPRS,WDR4,TYW5,FTSJ1,NUP62,TSEN15,NUP58,AAAS |
| 1.010e-04 | -9.20 | helicase activity | molecular function | GO:0004386 | 154 | 42 | 17224 | 2647 |
DDX58,RECQL,DDX47,SHPRH,TWNK,CHD1L,YTHDC2,DHX9,DHX8,SMARCA4,BLM,CHD1,DDX56,EIF4A3,MCM5,DDX31,AQR,GINS1,DDX28,SNRNP200,DDX24,BTAF1,HELB,DHX29,DDX20,MCM2,DDX39A,EIF4H,DHX15,DHX57,GINS4,RAD54B,DDX23,DDX17,XRCC5,UPF1,DHX16,CHD3,DDX5,RUVBL2,DDX52,DDX42 |
| 1.015e-04 | -9.20 | RPS10 (ribosomal protein S10) | protein interactions | 6204 | 165 | 46 | 17029 | 2761 |
RPS15,RPS2,CYLD,EWSR1,RPLP2,PTTG1,RPL15,CUL1,APP,CDC73,RPL11,RPL23A,EIF2S2,HUWE1,AHSA1,PIK3R2,RPL19,TMED2,PRPF19,RPL35,KAT7,RPL6,CUL3,RPL8,RPL38,RPS24,PRPF3,EIF2A,MCM2,RPL27A,RPS9,RPSA,EIF3A,CAND1,RPL36,EIF3K,RPS27A,RPS14,RPLP1,H2AFX,PRPF4,CHEK2,RRS1,CDK2,SMURF1,RPS26 |
| 1.017e-04 | -9.19 | CDC27 (cell division cycle 27) | protein interactions | 996 | 115 | 35 | 17029 | 2761 |
FOXM1,C16orf87,PTTG1,CCNB1,FOXO3,MAD2L2,FBXO5,RB1,PCNA,CCNA2,PTEN,PIN1,ANAPC7,MCPH1,TACC3,CDC5L,RRM2,ANAPC2,KRAS,DCLRE1C,UBE4B,AURKB,CDC23,PPP2CA,CDC16,SMAD2,CDC27,PPP2R5A,ELMO1,TFDP1,E2F1,RBPJ,USP11,PPP5C,ANAPC4 |
| 1.017e-04 | -9.19 | NDRG1 (N-myc downstream regulated 1) | protein interactions | 10397 | 115 | 35 | 17029 | 2761 |
EWSR1,SUZ12,S1PR2,PRKACA,COPB2,KIF5B,PSMD2,CLIC4,GART,RTCB,NAA50,ANXA5,RPN2,TARDBP,PABPC1,ACSL3,HNRNPF,LDHA,ILF3,PKM,EIF4H,RPS9,TARS,DHX15,CLNS1A,XRCC5,TIMM13,UPF1,ATP1A1,HSPA4,DDX5,RUVBL2,IGBP1,SINHCAF,RPS26 |
| 1.017e-04 | -9.19 | RRP8 (ribosomal RNA processing 8) | protein interactions | 23378 | 115 | 35 | 17029 | 2761 |
NIFK,URB2,MECP2,USP39,EBNA1BP2,BRIX1,RBM4,NVL,RBM34,POP7,NOC2L,RPF2,DDX31,FTSJ3,ZNF800,PPAN,NOL12,STAU1,DDX24,ZNF512,GTPBP4,RPL8,FXR1,MAK16,CENPU,RPL32,DGCR8,RPS14,ZNF689,PDCD11,ZC3HAV1,GPATCH4,IFI16,DDX52,CCDC137 |
| 1.017e-04 | -9.19 | CCND1 (cyclin D1) | protein interactions | 595 | 115 | 35 | 17029 | 2761 |
MCM10,TSC2,CUL1,PRKACA,CDK5,CDKN2C,RB1,MDM2,PCNA,PSMA6,PIN1,AKAP8,CDKN1B,POLR1B,CREB1,ATF2,STAT3,ARID4A,RBX1,MYBL2,CUL3,BRCA1,MCM2,KLF6,SLC25A5,POLR2A,UBTF,CDC27,RBL1,UHRF2,NCOA1,CDK2,MAPK1,HDAC2,CDKN2A |
| 1.017e-04 | -9.19 | FAS (Fas cell surface death receptor) | protein interactions | 355 | 115 | 35 | 17029 | 2761 |
INTS2,CTU2,CHD1L,ANK3,UBE2I,RUFY1,PDXDC1,WRB,CFLAR,MBD4,RB1,ATP6V0B,RAP1A,BABAM2,ARF5,FEM1B,GPD1L,TMX1,RHOA,RHOBTB3,FAM118B,EZR,ABHD11,SFXN5,FADD,FAS,KRIT1,PDCD6,WDR11,TIMM29,PML,RUVBL2,MAP3K5,HIPK3,FAF1 |
| 1.018e-04 | -9.19 | heterocycle catabolic process | biological process | GO:0046700 | 455 | 99 | 17256 | 2622 |
ADA2,RPLP2,RBM8A,ADPGK,SND1,PAIP1,PABPC4,EDC3,RPL23A,MBD4,RPL11,TET3,CSDE1,EIF4A3,METTL14,DUT,EXOSC1,RNASEH2A,OGG1,ENPP4,RPL29,RPL35,EXOSC6,POLR2G,RPL38,POLR2D,RNPS1,OGDH,RPS9,RPSA,RPL37,PPP2CA,HINT1,RPS27A,LSM6,RPS14,NT5C3B,RPLP1,DHTKD1,SMG9,NUDT11,RPS26,PFKP,GALK1,RPS15,RPS2,GSPT2,TATDN3,RPL15,PM20D2,THRAP3,PARN,CNOT11,METTL3,CNOT3,TUT4,NEIL2,PRPF18,PDXP,EXOSC7,RPL17,PPP1R8,PELO,DCP1A,RPL19,UPF2,AHCY,CNOT6L,PABPC1,SAMD4B,RNASEH2C,TRIR,NUDT4,RPL6,LDHA,RPL8,RPS10,RPS24,EXOSC9,PKM,PDE3B,RPL27A,PATL1,RPL36,HSPA1B,CNOT9,KPNA1,UPF1,RPL32,TATDN2,KHSRP,CNOT6,HMGB2,DNPH1,DDX5,GPI,TATDN1,PGAM1,NUDT3 |
| 1.028e-04 | -9.18 | MORF_JUND | MSigDB lists | MORF_JUND | 64 | 22 | 17377 | 2626 |
IER2,RHOA,RPLP2,NACA,RPL6,RPS24,MCL1,DAZAP2,RPL27A,EIF4G2,RPL11,RPL17,RPS27A,FBXO7,RBM3,RPL19,DDX5,BTF3,FAU,H3F3A,CFL1,PCBP2 |
| 1.040e-04 | -9.17 | KAUFFMANN_DNA_REPLICATION_GENES | MSigDB lists | KAUFFMANN_DNA_REPLICATION_GENES | 142 | 39 | 17377 | 2626 |
POLA2,PTMS,CHTF18,PTTG1,CENPF,RRM1,ORC1,BLM,WRNIP1,RPA2,PCNA,SMC3,MCM5,DUT,MSH2,ORC3,TMX1,SMC4,EIF5A,RFC3,PRIM2,KAT7,ABCF2,RRM2,CDC6,BRCA1,SMC2,MCM2,POLG2,RFC2,CHAF1A,RPA1,PPP2CA,NAP1L1,RBMS1,RBBP4,CDK2,PURA,POLQ |
| 1.045e-04 | -9.17 | XU_HGF_TARGETS_INDUCED_BY_AKT1_48HR_DN | MSigDB lists | XU_HGF_TARGETS_INDUCED_BY_AKT1_48HR_DN | 25 | 12 | 17377 | 2626 |
TXN,ASPM,GOLGA8A,KIF14,SUGP2,CENPF,CDCA3,KIF23,ZNF268,RBM12B,SMC4,PRPF4B |
| 1.045e-04 | -9.17 | MODULE_42 | MSigDB lists | MODULE_42 | 25 | 12 | 17377 | 2626 |
NDUFA5,NDUFV2,NDUFV1,NDUFS1,NDUFA2,NDUFA4,NDUFS8,NDUFA7,NDUFS5,NDUFB1,NDUFA3,NDUFS4 |
| 1.048e-04 | -9.16 | nuclear matrix | cellular component | GO:0016363 | 106 | 31 | 18223 | 2701 |
MBD1,NCOR2,DNMT3A,ATXN3,THOC1,PHB2,PSPC1,CXXC1,CENPF,ATXN1,GMCL1,BLM,MEN1,MATR3,HNRNPA2B1,PSMA6,AHCTF1,SMC3,CLIC4,NSMF,PPIG,AKAP8,PML,ZNF326,RNASEL,RUVBL2,YY1,OGG1,HNRNPM,CFL1,MORC3 |
| 1.048e-04 | -9.16 | MRPS14 (mitochondrial ribosomal protein S14) | protein interactions | 63931 | 41 | 17 | 17029 | 2761 |
NOL12,COX15,DDX56,RPS2,RBM42,MRPS2,MRPS15,USP42,RPL6,MRPS27,TUFM,ILF3,MPV17,MRPS10,TRMT10B,SNRNP70,ZC3H3 |
| 1.048e-04 | -9.16 | Integrated Cancer Pathway | WikiPathways | WP1971 | 46 | 18 | 5312 | 837 |
PLK1,BRCA1,BLM,RB1,SMAD2,MDM2,JAK1,PTEN,E2F1,MSH2,STAT1,CDKN1B,BCL2,CDC25B,CHEK2,MAP3K5,CDK2,MSH6 |
| 1.050e-04 | -9.16 | GO_REGULATION_OF_PROTEOLYSIS | MSigDB lists | GO_REGULATION_OF_PROTEOLYSIS | 683 | 139 | 17377 | 2626 |
XIAP,CUL1,CSNK2A1,SIRT2,UBQLN2,CCNB1,BIRC2,PARK7,FBXO22,CDK5,PSMD1,RAD23B,SENP1,PLK3,PLK1,BAK1,AKT2,PBK,RPS27A,PSMD8,AXIN1,PRDX5,SOCS4,OGT,ADAM9,CLU,DVL1,CLN3,ARRB2,PSMC1,HDAC2,SVIP,GORASP1,PHB2,DNAJB2,UBXN1,CENPF,NKD2,CYCS,PSEN1,PSMD9,RHBDD1,APOPT1,DDRGK1,TFAP4,CD59,RB1,DAPK1,ARL6IP1,SOCS5,GBA,PSMA1,CYFIP2,PSMB3,PSMC4,FAS,HSPBP1,GOLGA2,CDC27,SIAH2,GPI,MAP3K5,RNF14,RNF139,CDKN2A,RNF114,ZNF207,RAF1,CAST,RPS6KA1,PTTG1,SUMO2,MYH9,PRKACA,BCAP31,APP,ANKIB1,RAD23A,USP5,APLP2,PSMA6,MDM2,TNFAIP8,UCHL5,PDCD2,CDKN1B,PARL,ANAPC7,RNF19A,CLN6,F2R,PDCL3,HTRA2,UBQLN4,TIMP2,BIRC3,PSMA8,CUL3,PSMB7,CDC23,RAB1A,PSMB9,IDE,CDC16,NSMCE2,PSMD3,XRCC3,TRIM32,SMURF1,GEN1,CSNK1D,BCL2L12,DAP,PAWR,CSNK1A1,MAD2L2,FBXO5,PSMD2,PTEN,LDLRAD3,STAT3,RFFL,ANAPC2,PICALM,FADD,GNA12,PDCD6,KEAP1,LTBP4,PRDX3,BIRC5,GLG1,PML,UBE2C,IGBP1,ESPL1,TERF1,IFI16,ANAPC4 |
| 1.052e-04 | -9.16 | DNAJB1 (DnaJ heat shock protein family (Hsp40) member B1) | protein interactions | 3337 | 102 | 32 | 17029 | 2761 |
HSPH1,EWSR1,NQO1,UBQLN2,XPO7,APP,ANKRD28,MDM2,HUWE1,DPYSL2,TARDBP,PTGES3,TTLL12,NUDC,CDC37,TELO2,NRAS,PTPN18,DCAF6,CUL3,ADSL,EDF1,BRCA1,ISG15,BRMS1,MAGED2,HSPA4,WDR4,WIPI2,ECPAS,TERF1,POT1 |
| 1.052e-04 | -9.16 | cellular response to oxidative stress | biological process | GO:0034599 | 226 | 56 | 17256 | 2622 |
TXN,NQO1,RWDD1,PRKAA1,PXMP2,CYCS,SIRT2,BECN1,ETS1,FOXO3,PARK7,SRXN1,CFLAR,PDK2,PDCD10,CCNA2,MDM2,PCNA,ATP2A2,DNM2,DAPK1,BCL2,HTRA2,PTPRK,TXNL1,PPIF,STAU1,TNFAIP3,NET1,OXR1,ERO1A,GBA,PRKRA,MTR,RHOB,PRDX1,HSPA1B,MAPK3,CAT,ANKZF1,ALDH3B1,PRDX3,GUCY1B1,STAT6,ARNTL,PRDX5,MPV17,PML,PKD2,MAP3K5,PPP5C,CDK2,MAPK1,CPEB2,HDAC2,ADNP2 |
| 1.053e-04 | -9.16 | ncRNA transcription | biological process | GO:0098781 | 90 | 28 | 17256 | 2622 |
INTS2,NIFK,GTF3C6,POLR2I,RPRD1A,POLR2G,POLR2L,POLR2K,ELL2,INTS13,POLR2D,GTF3A,SNAPC4,SRRT,POLR2A,GTF2F1,CCNK,POLR2J,CD3EAP,INTS7,INTS1,NABP1,NABP2,INTS12,ICE2,POLR1B,TAF6,RPRD1B |
| 1.053e-04 | -9.16 | THUM_SYSTOLIC_HEART_FAILURE_UP | MSigDB lists | THUM_SYSTOLIC_HEART_FAILURE_UP | 381 | 85 | 17377 | 2626 |
MAX,ENSA,YTHDF3,CCNL2,DAZAP2,PPP1R16B,LYN,PAPOLA,PRNP,SHC1,RALB,LMAN1,PDIA6,CDC5L,CCT2,ZNF672,LAP3,FOPNL,ZBED5,EZR,HTATIP2,ARHGDIB,NFATC2,ZFAND5,MAT2A,PLEKHF2,IWS1,HSPA4,SEC61A1,UEVLD,GADD45B,ARNTL,STAT1,ITGB1,LMBR1,ADAM9,ACTB,PRPF4B,SCOC,SRGN,RRM1,SDC2,TATDN3,ARF1,NOTCH2,XPO7,GFM2,MAN1A1,PPP1R3B,CLIC4,CTSS,KLHL20,INPP5A,TANK,PTPN11,ANP32A,KIFAP3,PIK3IP1,SGCB,TMED2,HP1BP3,JMJD4,ADAM17,RHOA,WDR1,PSPC1,BCLAF1,PRMT2,MATR3,PICALM,SPPL2B,FAS,MFN2,AKAP1,CAT,SCARB2,KPNA4,SNAP23,PGRMC1,SLC16A1,YWHAZ,PREPL,RBBP4,EHD4,RNF14 |
| 1.056e-04 | -9.16 | HIRSCH_CELLULAR_TRANSFORMATION_SIGNATURE_DN | MSigDB lists | HIRSCH_CELLULAR_TRANSFORMATION_SIGNATURE_DN | 95 | 29 | 17377 | 2626 |
PTMS,DCAF6,NQO1,KIAA0100,HARS,SRSF6,KIAA0930,CENPF,STARD7,RACGAP1,ARHGDIB,HMGN3,BCLAF1,GALNT7,NCAPG,PARN,SRRT,COMMD8,DLG5,DST,TNS3,SYNCRIP,DPYSL2,TTC3,NR2F2,ZMIZ1,PTDSS1,TOB1,PTPRK |
| 1.061e-04 | -9.15 | aromatic compound catabolic process | biological process | GO:0019439 | 472 | 102 | 17256 | 2622 |
ADA2,RPLP2,RBM8A,ADPGK,SND1,PAIP1,PABPC4,EDC3,RPL23A,MBD4,RPL11,TET3,CSDE1,EIF4A3,METTL14,DUT,EXOSC1,RNASEH2A,OGG1,ENPP4,RPL29,RPL35,EXOSC6,POLR2G,HPDL,RPL38,POLR2D,RNPS1,OGDH,RPS9,RPSA,RPL37,PPP2CA,PON2,HINT1,RPS27A,LSM6,RPS14,NT5C3B,RPLP1,DHTKD1,SMG9,NUDT11,RPS26,PFKP,GALK1,RPS15,RPS2,GSPT2,TATDN3,RPL15,PM20D2,THRAP3,PARN,CNOT11,EPHX2,METTL3,CNOT3,TUT4,NEIL2,PRPF18,PDXP,EXOSC7,RPL17,PPP1R8,PELO,DCP1A,RPL19,UPF2,AHCY,CNOT6L,PABPC1,SAMD4B,RNASEH2C,TRIR,NUDT4,RPL6,LDHA,RPL8,RPS10,RPS24,EXOSC9,PKM,PDE3B,RPL27A,PATL1,RPL36,HSPA1B,CNOT9,KPNA1,UPF1,RPL32,TATDN2,KHSRP,CNOT6,HMGB2,DNPH1,DDX5,GPI,TATDN1,PGAM1,NUDT3 |
| 1.064e-04 | -9.15 | GGCAGCT,MIR-22 | MSigDB lists | GGCAGCT,MIR-22 | 217 | 54 | 17377 | 2626 |
SMAP1,MAX,PPP1R15B,MECP2,PDAP1,FAM53C,ZFP91,SLC2A1,OLA1,WDTC1,PLAGL2,ARFIP2,MXD4,RGS2,MAPK14,MXD1,EDC3,WRNIP1,FBRS,CALM2,CLIC4,THADA,PTEN,COPS7B,RBM3,CLDND1,LDLRAD3,RBM15,FBXL19,ASB6,SRSF10,FTL,PHF20L1,BRD4,FAM49B,NET1,NUDT4,CUL3,RFXANK,ARHGEF12,LRRC1,SLC17A5,HERPUD2,KDM3A,RAB5B,DHX57,MAT2A,DPYSL3,VEZF1,MTHFD2,RNF38,NAA20,H3F3A,BTBD10 |
| 1.065e-04 | -9.15 | KEGG_RIBOSOME | MSigDB lists | KEGG_RIBOSOME | 86 | 27 | 17377 | 2626 |
RPS15,RPL29,RPL35,RPS2,RPLP2,RPL8,RPS10,RPL6,RPL38,RPL15,RPS24,RPL27A,RPS9,RPSA,RPL11,RPL23A,RPL36,RPL37,RPL32,RPL17,RPS27A,RPLP1,RPL19,FAU,MRPL13,RPS26,RPL22L1 |
| 1.065e-04 | -9.15 | NGUYEN_NOTCH1_TARGETS_DN | MSigDB lists | NGUYEN_NOTCH1_TARGETS_DN | 86 | 27 | 17377 | 2626 |
PPIF,TRIP12,KLF10,NOP2,ELL2,NET1,TRIO,MEF2A,CADM1,USP22,RGS2,PSMB9,SLC20A1,CDK11A,SERP1,TARS,ZNF282,MTHFD2,BRD2,ETS2,HUWE1,GADD45B,RBMS1,SLC12A2,TIPARP,HTRA2,SRPK2 |
| 1.070e-04 | -9.14 | Formation of a pool of free 40S subunits | REACTOME pathways | R-HSA-72689 | 105 | 33 | 10287 | 1696 |
RPS15,RPS2,RPLP2,EIF3D,RPL15,RPL11,RPL23A,RPL17,RPL19,RPL22L1,EIF3L,RPL29,RPL35,RPL38,RPL6,RPS10,RPL8,RPS24,RPL27A,EIF3G,RPS9,EIF3A,EIF3H,RPSA,RPL36,RPL37,EIF3K,RPL32,RPS27A,RPS14,RPLP1,FAU,RPS26 |
| 1.071e-04 | -9.14 | GO_FC_EPSILON_RECEPTOR_SIGNALING_PATHWAY | MSigDB lists | GO_FC_EPSILON_RECEPTOR_SIGNALING_PATHWAY | 123 | 35 | 17377 | 2626 |
VAV2,RAC1,CUL1,PPP3CB,PSMD9,LYN,CALM2,VAV1,PSMD2,NFATC3,PSMD1,PSMA6,SHC1,PIK3R2,PDPK1,PPP3CA,NRAS,PSMA8,PSMB7,PSMA1,NFATC2,UBE2V1,KRAS,PSMB9,PSMB3,MAPK3,PSMC4,TAB2,RPS27A,PSMD3,PSMD8,PPP3R1,MAPK1,HRAS,PSMC1 |
| 1.077e-04 | -9.14 | DEURIG_T_CELL_PROLYMPHOCYTIC_LEUKEMIA_DN | MSigDB lists | DEURIG_T_CELL_PROLYMPHOCYTIC_LEUKEMIA_DN | 290 | 68 | 17377 | 2626 |
UBL3,CYLD,PNISR,LUZP1,THOC1,FAM129A,TOR1AIP1,USP48,PPP1R16B,GIT2,SLC25A37,CREM,C2orf68,CDKN2C,KDM2A,CDC42,RABGAP1L,ZCCHC2,TARDBP,RNF19A,TIPARP,F2R,SAP30L,CDKN2AIP,BIRC3,BAZ2A,ZBED5,ATXN1,DCLRE1C,EML4,OPTN,TAB2,ARNTL,NCOA1,GALNT10,H3F3A,FAM208A,PFKP,FUBP1,WSB2,RECQL,NDUFV2,PPP1R12A,SRGN,HABP4,BRAP,GGA2,REEP5,MAN1A1,CFLAR,CAPN2,CD59,CTR9,BCL2,STAT3,SGCB,TRAFD1,ACSL3,PPWD1,SRSF5,ADRB2,FAS,PCM1,HNRNPH3,ACAT1,MAP3K5,CHMP7,N4BP2L2 |
| 1.078e-04 | -9.14 | SANT/Myb | interpro domains | IPR001005 | 44 | 17 | 18492 | 2768 |
DNAJC2,NCOR2,TRERF1,MTA2,MIER1,MYBL2,RCOR1,MIER2,EZH1,RCOR3,TTF1,SNAPC4,MTA1,MYBL1,TERF1,CDC5L,TERF2 |
| 1.086e-04 | -9.13 | small GTPase mediated signal transduction | biological process | GO:0007264 | 315 | 73 | 17256 | 2622 |
RHOG,WASF2,RAB14,NF1,RAB11B,RAC1,RRAGC,MAPK14,PARK7,CRKL,VAV1,RAB21,RAB8A,CCNA2,RAP1A,SHC1,CDC42,RALB,RAB35,RAB4A,DNMT1,CFL1,CHP1,SHOC2,RHOBTB3,NRAS,RAB7A,RAB1A,RAB5B,TRIM28,RAB22A,RAB2B,KRIT1,WAS,RAB24,LIMK1,ROCK1,SH2D3A,RHOC,VAV2,RAB23,ARFIP2,BRAP,NCKAP1,RAB6A,MYO9B,DOCK11,IFT27,RAB11A,RAPGEF6,RTKN,RB1,ARHGEF1,CYFIP1,RHOA,MAPKAPK3,RFXANK,RABIF,ARHGEF12,KRAS,RIT1,RHOT1,RHOT2,RHOB,RAB18,GNA12,ELMO1,SIAH2,RGL1,CDK2,HRAS,CDKN2A,ALS2 |
| 1.090e-04 | -9.12 | ATF7IP (activating transcription factor 7 interacting protein) | protein interactions | 55729 | 85 | 28 | 17029 | 2761 |
MBD1,EWSR1,TRIP12,POLR2G,VHL,MRI1,SUMO2,RPL8,POLR2D,CADM1,AP1B1,UBE2I,ZNF518A,MACF1,POLR2A,MAPK3,GTF2F1,HLA-B,GMEB1,RRBP1,PML,DNM2,TTC3,ACTB,CREB1,SMAD4,LUC7L2,RYBP |
| 1.090e-04 | -9.12 | Bax (BCL2-associated X protein) | protein interactions | 12028 | 7 | 6 | 17029 | 2761 |
MCL1,BCL2,DNAJA1,BCL2L1,HSPA4,PARK7 |
| 1.090e-04 | -9.12 | PXDNL (peroxidasin like) | protein interactions | 137902 | 7 | 6 | 17029 | 2761 |
OSTF1,PPP1R16B,CARM1,CUTA,CUL3,SPTAN1 |
| 1.093e-04 | -9.12 | GO_CYTOSKELETON_DEPENDENT_INTRACELLULAR_TRANSPORT | MSigDB lists | GO_CYTOSKELETON_DEPENDENT_INTRACELLULAR_TRANSPORT | 109 | 32 | 17377 | 2626 |
KIF3B,DYNLL1,AP3M2,KIF23,RAB6A,AP3S1,IFT27,APP,KIF5B,STARD9,RAB21,CDC42,AP3S2,KIF13B,KIF14,KIFAP3,IFT46,MYO5A,BICD2,WDR81,RAB1A,RHOT1,RHOT2,BBS12,TMEM201,PCM1,LRPPRC,SSNA1,CLN3,NDE1,TUBB,SNAPIN |
| 1.094e-04 | -9.12 | DYNLRB1 (dynein light chain roadblock-type 1) | protein interactions | 83658 | 27 | 13 | 17029 | 2761 |
HSPH1,MAPRE1,MPHOSPH8,TCTEX1D2,CENPJ,SAFB,DYNLL1,DCTN2,MRPS26,CUL3,PLOD3,KIF11,DYNC1LI2 |
| 1.094e-04 | -9.12 | MGST3 (microsomal glutathione S-transferase 3) | protein interactions | 4259 | 27 | 13 | 17029 | 2761 |
CCNC,UNK,RAP1A,FAM3C,MRPS26,ATP6V0A1,MCM2,ATP6V1C1,HRAS,LMNA,NMT2,NDUFS4,SVIP |
| 1.094e-04 | -9.12 | ARL4D (ADP ribosylation factor like GTPase 4D) | protein interactions | 379 | 27 | 13 | 17029 | 2761 |
TERF2IP,EPRS,SMAD2,PRKCSH,ARL6IP1,CNPY4,DNAJA1,SMAD1,PGAM1,SMURF1,EML4,APP,TERF2 |
| 1.097e-04 | -9.12 | BONOME_OVARIAN_CANCER_SURVIVAL_SUBOPTIMAL_DEBULKING | MSigDB lists | BONOME_OVARIAN_CANCER_SURVIVAL_SUBOPTIMAL_DEBULKING | 486 | 104 | 17377 | 2626 |
UBL3,TMED7,PNISR,ST13,DCAF15,YTHDC2,TAF6L,TWF2,PRKACA,ZNF696,BCAT2,ZER1,DST,VAV1,FARSA,PRKD3,DBNDD1,IL6ST,PIK3R2,ADCY9,PDS5B,MRPS27,TNPO2,F2R,CLN6,ASB6,COPS8,RHOBTB3,FAM172A,EID1,AZI2,ICMT,OGFR,CHAF1A,SUGP1,WAS,ATXN2L,TICAM1,BTF3,AAAS,GALK1,CDC40,SH2D3A,MUT,ANXA6,MECP2,ADO,GNE,VAV2,DHX9,SDC2,CERK,EPN1,ASAH1,PPP3CB,RAB6A,MYO9B,ZNF518A,SRRT,REEP5,METTL3,DNAJB9,KRI1,RNF121,RB1,ARHGEF1,PHF14,ARHGEF2,YBX1,MORC3,PPAN,SRSF11,TELO2,PPP3CA,SNX2,MAPKAPK3,RB1CC1,DHX29,ACSL3,SUGP2,MYBL2,ITM2A,KCNQ1,SEPT7,RHOT1,ARMC8,NMT2,PDCD6,SEC23IP,UPF1,TMEM168,ODF2,DCAF11,CCDC69,ATP6V1C1,MAP3K5,NR2F2,CDK2,PDSS2,ESPL1,BYSL,DEF6,IPO4,DDX52 |
| 1.103e-04 | -9.11 | transcription coactivator activity | molecular function | GO:0003713 | 317 | 74 | 17224 | 2647 |
RORB,MAX,TRERF1,MAGED1,SMARCA4,TAF6L,BIRC2,PARK7,GLMP,SP100,MTA1,GMEB1,LPIN2,TAF5L,ECD,SMARCE1,ATF2,CCAR1,CARM1,POU2AF1,GABPA,WBP2,HTATIP2,EDF1,USP22,BRCA1,SOX4,CBFB,USP21,TRIM28,DDX17,HIPK2,PQBP1,ATF6,TRIM32,NCOA1,FUS,SLC30A9,POU3F2,TCF3,DHX9,MEF2A,THRAP3,PMF1,SUPT7L,PSMD9,ARID1B,JMY,GTF2F1,TFAP4,SUB1,RB1,BUD31,BRD7,SS18L1,MAML1,CITED2,NCOA2,DCAF6,KAT2A,ARID1A,PRMT2,RXRB,SERTAD2,PDLIM1,GPS2,SETD3,TFDP1,TBPL1,PIAS2,TAF12,YY1,RNF14,SMARCD1 |
| 1.104e-04 | -9.11 | RPS21 (ribosomal protein S21) | protein interactions | 6227 | 111 | 34 | 17029 | 2761 |
RPS2,CYLD,RPLP2,DYNLL1,RPL15,CUL1,APP,RPL11,RPL23A,PSMD2,PSMD1,RPL17,UCHL5,RAD23B,RPL19,PABPC1,HNRNPM,CUL3,RPL6,RPS10,RPS24,SLC25A5,RPS9,CLNS1A,RPSA,CAND1,SYNCRIP,PSMD3,PSMD8,RPLP1,CDK2,RPS26,PSMC1,ANXA11 |
| 1.104e-04 | -9.11 | Hodgkin_lymphoma | COSMIC cancer mutations | Hodgkin_lymphoma | 29 | 13 | 17385 | 2587 |
CDKN2C,SEC31A,PCM1,CYLD,NRAS,TNFAIP3,PTEN,SF3B1,ETV6,KRAS,STAT3,HRAS,CDKN2A |
| 1.105e-04 | -9.11 | Helicase_ATP-bd | interpro domains | IPR014001 | 110 | 32 | 18492 | 2768 |
DDX58,RECQL,DDX47,SHPRH,YTHDC2,CHD1L,DHX9,SMARCA4,DHX8,BLM,CHD1,DDX56,EIF4A3,DDX31,DDX28,SNRNP200,DDX24,DHX29,BTAF1,DDX20,DDX39A,DHX57,DHX15,DDX17,DDX23,RAD54B,DHX16,CHD3,DDX5,DDX42,POLQ,DDX52 |
| 1.108e-04 | -9.11 | CHEN_HOXA5_TARGETS_9HR_DN | MSigDB lists | CHEN_HOXA5_TARGETS_9HR_DN | 36 | 15 | 17377 | 2626 |
UBTF,WNT5B,FJX1,H2AFX,GLG1,TMEM97,AP1S1,ANP32A,SLC29A1,GEMIN4,LPCAT1,GM2A,MAT2A,KDELR1,AKAP1 |
| 1.111e-04 | -9.11 | NUYTTEN_EZH2_TARGETS_UP | MSigDB lists | NUYTTEN_EZH2_TARGETS_UP | 968 | 188 | 17377 | 2626 |
UBL3,UBE2E2,MAX,AGRN,TMEM41B,TAP1,TMEM109,NHLRC3,PLXNA1,CDC42SE2,BIRC2,KRR1,PRNP,ABL2,NEK6,CDC42,JAZF1,IL6ST,PHTF1,CISD2,RP2,TFG,SPTSSA,EIF5,TRIM14,KCNAB2,WDR41,FYTTD1,DEAF1,NCK1,LAP3,SLC16A7,LACTB,MCL1,DCUN1D5,PITPNB,ICMT,OPTN,ANKRD10,TRIM47,TMED10,LIMK1,OGT,CAB39,SMAD1,DCAF5,NXT2,DDX58,HIVEP3,PARP12,HLA-E,RHOC,KLC1,RLF,ITGB5,CFLAR,FKBP1A,CD59,SUB1,ARL6IP1,MVP,MORC3,SOCS5,CYTH1,WDR1,SUGP2,ADRB2,KDM3A,ARMC8,ZDHHC3,CYB5A,ANKRD46,FAS,ADSS,PTPRF,SCARB2,RBM25,UAP1,ETS2,TTC13,DUSP3,NUP62,YWHAZ,TMEM159,APOL2,ZC3HAV1,RNF114,EGLN1,DNMT3A,CYLD,CAST,SLC2A1,ACTR3,SLC39A13,ZNF121,APP,MXD1,APLP2,UBXN2A,TNFAIP8,ZNF302,IARS,SP100,ATP2A2,SAR1A,ZCCHC2,CLCN6,BRI3,RPN2,TP53BP2,CYB5R1,TMEM14C,MOSPD1,ATP6V1G1,PPIF,ARHGAP17,BIRC3,KIAA0040,LRRC8A,TOR1AIP2,EDF1,DNAJA1,AZI2,HERPUD2,PSMB9,ARL5B,SERP1,PPP2CA,PON2,TAB2,CORO1C,STAT1,TICAM1,SCARB1,XRCC4,COMMD10,KLHL21,B4GALT5,MECP2,AGPAT3,SECISBP2,LANCL1,DCUN1D4,GFM2,PIP4K2A,DNAJB9,PNO1,MAN1A1,SLC25A36,SRXN1,MAT2B,CLIC4,KLHL20,TANK,FUT8,RRBP1,AXIN2,ANXA5,MAP3K14,OSTC,TPCN1,PHF20L1,ADAM17,ANKRD37,TNFAIP3,POLK,DENND1B,USP42,LDHA,KCNQ1,KLF6,PRDX1,HLA-B,TMEM127,ZHX1,MFAP1,FAM3C,OAZ2,MAPK6,GLG1,PML,RBPJ,RGL1,NR2F2,RPS6KC1,CPEB2,IFI16,TMEM131 |
| 1.111e-04 | -9.10 | skin-arm-benign_melanocytic_nevus-Spitz | COSMIC cancer mutations | skin-arm-benign_melanocytic_nevus-Spitz | 22 | 11 | 17385 | 2587 |
KIF5B,PWWP2A,NRAS,ZCCHC8,KRAS,HRAS,ERC1,HLA-A,MYO5A,LMNA,DCTN1 |
| 1.115e-04 | -9.10 | ovary-carcinoma-small_cell_carcinoma | COSMIC cancer mutations | ovary-carcinoma-small_cell_carcinoma | 125 | 35 | 17385 | 2587 |
DNMT3A,CYLD,TSC2,ARID2,NF1,SF3B1,SMARCA4,NOTCH2,CDC73,CDKN2C,FGFR3,RB1,PTEN,MSH2,PTPN11,MSH6,NRAS,TNFAIP3,CIC,VHL,KRAS,BRCA1,PBRM1,ARID1A,MEN1,KMT2C,MAP2K2,GNAS,TSC1,JAK1,STK11,HRAS,SMAD4,CDKN2A,FUBP1 |
| 1.123e-04 | -9.09 | NCOR1 (nuclear receptor corepressor 1) | protein interactions | 9611 | 175 | 48 | 17029 | 2761 |
NCOR2,FGFR1OP,ATXN3,EWSR1,KDM4A,PHB2,MECP2,CSNK2A1,SMARCA4,UBE2I,SAFB2,ETS1,CHD1,KIF5B,HDAC7,ETV6,EXOSC1,PDCD2,CREB1,SMARCE1,SAP30,FOXK1,ZMYND11,MYBL2,ATXN1,DDX20,CBFA2T2,KIF11,TRIM28,IRF5,KPNA1,CDC16,KIF18A,HSPA4,ETS2,GPS2,TAB2,SAFB,PML,YWHAZ,RBPJ,NCOA1,RBBP4,TAF6,EYA2,SMAD4,CDKN2A,SMARCD1 |
| 1.124e-04 | -9.09 | GSE17721_CTRL_VS_CPG_1H_BMDC_UP | MSigDB lists | GSE17721_CTRL_VS_CPG_1H_BMDC_UP | 192 | 49 | 17377 | 2626 |
PRKAB1,C19orf53,TMEM203,ZCCHC8,IVNS1ABP,TRIM11,RAC1,GADD45G,MRPS26,RAB23,TM9SF3,NANS,COPG2,MRPL19,CDKN2C,RNFT1,MTA1,MRPL34,TNPO3,CYB5R1,FAM76B,PHKG2,TMEM14C,KCNAB2,CGGBP1,TIMM50,ADCY7,NRAS,PPP1R21,KIAA0930,JTB,PIP4K2C,SEPT8,FBXO9,CAPZA2,MCM2,SLC50A1,BTBD1,STOML2,NEK1,GOLGA7,TMED10,MFAP1,LIMK1,ACLY,NCLN,ZFP90,FUBP1,STARD3NL |
| 1.124e-04 | -9.09 | GSE42021_CD24HI_VS_CD24INT_TCONV_THYMUS_UP | MSigDB lists | GSE42021_CD24HI_VS_CD24INT_TCONV_THYMUS_UP | 192 | 49 | 17377 | 2626 |
TMEM106C,DEPDC1,GSPT2,MOGS,CERK,CSNK2A1,KLC1,SLC20A1,WRB,ANKRD28,ZNF428,MEX3C,LRRC8D,GOT2,SIVA1,HADHB,SOCS6,ARHGEF2,ANP32A,JOSD1,CENPM,METTL9,MYBL1,CYTH1,RPRD1A,DCAF6,ZNF500,ZBED5,EMP3,SOX4,ZFAND5,ODC1,NDRG3,SRSF1,DERL1,TBC1D17,PLAA,ETS2,BRWD1,TFE3,APPL2,MEGF9,GALNT10,RNASEL,RRS1,WDR91,ZMIZ1,TAF6,TOB1 |
| 1.124e-04 | -9.09 | GSE23398_WT_VS_IL2_KO_CD4_TCELL_SCURFY_MOUSE_UP | MSigDB lists | GSE23398_WT_VS_IL2_KO_CD4_TCELL_SCURFY_MOUSE_UP | 192 | 49 | 17377 | 2626 |
INTS2,DNAJC2,PKP4,AGRN,HLA-E,CHD1L,PTTG1,PAWR,BZW2,NUP205,KRI1,LYAR,NUDT19,PCNA,IARS,AHSA1,MCM5,EXOSC1,NUP107,GEMIN6,DNMT1,PPA1,ANKRD9,DDX24,LONRF3,KAT2A,ELL2,MAP4K3,SMC2,GAR1,ODC1,TSR2,GNAS,HLA-B,PLD3,BOLA3,MTHFD2,SERF2,TONSL,CHCHD1,FAM3C,CANT1,COX5A,CENPT,NR2F2,CBX4,ANXA11,FAM83G,CCDC137 |
| 1.124e-04 | -9.09 | GSE26669_CD4_VS_CD8_TCELL_IN_MLR_UP | MSigDB lists | GSE26669_CD4_VS_CD8_TCELL_IN_MLR_UP | 192 | 49 | 17377 | 2626 |
EXOC3,CORO7,MAGED1,ANKH,B4GALT4,CDIPT,DCUN1D4,PSMD9,PRNP,PTPN2,FKBP1A,RB1,RABGAP1L,BDH1,FUT8,RCSD1,ORAI1,BCL2,CITED2,CTDSP2,ARL5A,PPA1,SLC25A1,FDFT1,GTF3C6,MKLN1,LONRF3,RBX1,NUDT4,ITM2A,WDR82,FAM133B,MAP4K3,EAF2,PRPSAP1,NDRG3,RBM38,CAND1,DNAJC10,DAP3,ETS2,PSMD3,HAGHL,BEND6,RPS26,LRP8,LONP2,BYSL,ZC3HC1 |
| 1.124e-04 | -9.09 | GO_DNA_RECOMBINATION | MSigDB lists | GO_DNA_RECOMBINATION | 192 | 49 | 17377 | 2626 |
POLA2,RECQL,NSMCE4A,TCF3,RMI2,SMC6,TOP2B,INO80E,BLM,RMI1,RPAIN,WDR48,RPA2,PCNA,UCHL5,XRCC2,MSH2,MSH6,ERCC1,MND1,RFC3,EXOSC6,PRIM2,RAD51AP1,PRKDC,TOP3A,BRCA1,DCLRE1C,RFC2,GINS4,RAD54B,PRIM1,XRCC5,RPA1,RAD51C,PALB2,POLE,TONSL,NSMCE2,H2AFX,XRCC3,HMGB2,RBPJ,RUVBL2,YY1,XRCC4,GEN1,RAD51D,POLQ |
| 1.124e-04 | -9.09 | GSE9316_IL6_KO_VS_IFNG_KO_INVIVO_EXPANDED_CD4_TCELL_UP | MSigDB lists | GSE9316_IL6_KO_VS_IFNG_KO_INVIVO_EXPANDED_CD4_TCELL_UP | 192 | 49 | 17377 | 2626 |
TRIM41,ABCA3,ADD1,COPA,GNPDA1,MANBA,HABP4,HEXB,SUMF1,SIKE1,MAN2B1,EZH1,UBQLN2,GGA2,STMN1,MAPK14,TCF19,ITGB5,LCLAT1,FOXO3,GSTK1,SSBP3,CYB5R1,PLCL2,RBM15,CTDSP2,POU2AF1,TIMP2,MLEC,LRBA,HTATIP2,DNAJC9,CADM1,ESYT1,WBP1,TAZ,CYB5A,CAT,DUSP3,CLK3,UEVLD,ARNTL,MYO18A,COX7A2L,GLG1,ACAT1,GALNT10,LTA4H,ZMAT3 |
| 1.129e-04 | -9.09 | COPA (coatomer protein complex subunit alpha) | protein interactions | 1314 | 98 | 31 | 17029 | 2761 |
UNK,STAU1,COPA,SEPT9,TRIP10,SF3B1,SUZ12,COPE,WBP2,DDX20,BRCA1,WBP1,SDHA,MATR3,COPG2,COPB2,RPA1,RPA2,DSN1,TMED10,SEC24C,DDA1,PPM1G,ZNF746,XRCC3,CRY2,SRSF3,LMAN1,CDK2,TMED2,CDC5L |
| 1.129e-04 | -9.09 | APEX1 (apurinic/apyrimidinic endodeoxyribonuclease 1) | protein interactions | 328 | 98 | 31 | 17029 | 2761 |
METTL1,TXN,PSMG1,CSNK2A1,BRCA1,UBE2I,TWF2,SDHA,APP,RPSA,RPA1,XRCC5,TFAP4,TERF2IP,RPA2,MDM2,PCNA,ANP32A,YBX1,HMGB2,STAT3,TERF1,PABPC1,NUDT3,HDAC2,CGGBP1,DDB1,PRPF19,SRPK2,TERF2,DCTN1 |
| 1.129e-04 | -9.09 | DDX56 (DEAD-box helicase 56) | protein interactions | 54606 | 98 | 31 | 17029 | 2761 |
PPAN,RPL29,NOP2,AATF,DDX24,SUZ12,MECP2,MRPL43,GTPBP4,CUL1,EBNA1BP2,BRIX1,MRPS14,RPS9,DHX57,RPL23A,CAND1,KRR1,RPL37,DDX56,EIF2S2,DGCR8,RBM34,TBL3,NOC2L,RPF2,RRS1,FBL,FTSJ3,IFI16,GPATCH4 |
| 1.130e-04 | -9.09 | GSE27786_LIN_NEG_VS_ERYTHROBLAST_UP | MSigDB lists | GSE27786_LIN_NEG_VS_ERYTHROBLAST_UP | 187 | 48 | 17377 | 2626 |
MBD1,RAB14,TOR3A,GYG1,LYN,IFT27,MRPL50,FARSA,MED10,COQ4,SAR1A,ARHGEF1,GEMIN6,MCMBP,SGCB,NDUFA3,ARL5A,HTRA2,GM2A,SLC25A1,NIPSNAP1,B3GALT6,TELO2,TIMM8B,RHOBTB3,SIGMAR1,GABPA,LAP3,NCK1,NUP155,LRRC1,TOMM40,CBFA2T2,COMMD4,BTBD1,AMZ2,UTP20,TPD52L2,MRPL2,TRAM2,TRIM47,GALNT2,PEX5,TMEM168,CCDC86,CORO1C,NLRC5,PKD2 |
| 1.130e-04 | -9.09 | GSE1448_CTRL_VS_ANTI_VALPHA2_DP_THYMOCYTE_UP | MSigDB lists | GSE1448_CTRL_VS_ANTI_VALPHA2_DP_THYMOCYTE_UP | 187 | 48 | 17377 | 2626 |
RHOG,SART1,GPR132,FOXM1,CDCA3,UCK1,UBE2Z,PMF1,CNTROB,SPAG5,SAC3D1,RPA2,PRKD3,CLIC4,UCHL5,PPIG,RRBP1,MECR,GTSE1,BCL2,IFT46,HDHD2,SLC25A1,DEAF1,STAU1,TK1,RFC3,PPT1,ASPM,USP22,RFC2,RAB5B,LUC7L,SPPL2B,DPYSL3,MAP3K4,TSC1,PCM1,MRPL55,U2SURP,E2F1,AP1S1,VPS4A,GALNT10,PLOD3,PPP5C,ZC3HC1,RAD51D |
| 1.130e-04 | -9.09 | GSE5679_CTRL_VS_PPARG_LIGAND_ROSIGLITAZONE_TREATED_DC_DN | MSigDB lists | GSE5679_CTRL_VS_PPARG_LIGAND_ROSIGLITAZONE_TREATED_DC_DN | 187 | 48 | 17377 | 2626 |
MIB2,GGNBP2,AGRN,TRIM11,FAM129A,PTTG1,KIAA0232,HABP4,CCNL2,PRPF39,DCUN1D4,RGS2,SLC20A1,ETS1,ITGB5,LCLAT1,CRKL,ITGB8,RABGAP1L,AKAP8,CDKN1B,CISD2,MCMBP,ARID4A,PREB,TNFAIP3,KRAS,ARHGEF12,SLC17A5,HERPUD2,STX16,KLF6,BSDC1,DERL1,MAN2A2,HLA-B,ZNF862,AHNAK,TPP2,OAZ2,ZC3H7B,DDX5,ROCK1,WDR91,USP11,CPEB2,ZC3HAV1,RHEBL1 |
| 1.130e-04 | -9.09 | GSE27786_NKCELL_VS_NEUTROPHIL_UP | MSigDB lists | GSE27786_NKCELL_VS_NEUTROPHIL_UP | 187 | 48 | 17377 | 2626 |
RAB14,NSMCE4A,GNPNAT1,KIAA0100,CTCF,UCK1,SLC35B1,GGA2,OAT,ASXL2,REEP5,METTL3,POLR3K,EXT2,NDUFS7,RRP36,TMCC3,SAP130,UBXN2A,MTMR4,IL6ST,ETV6,EXOSC1,ZNF260,MECR,GLTP,RNASEH2A,AQR,NSUN4,CDC5L,METTL1,DDX24,SNX2,MRPL12,SCFD2,ADSL,BCLAF1,CAPZA2,DTWD1,CDC16,PDLIM1,NIP7,PPM1G,PPA2,ZFP90,PDXK,PSAP,RHEBL1 |
| 1.130e-04 | -9.09 | GSE29949_CD8_NEG_DC_SPLEEN_VS_CD8_POS_DC_SPLEEN_DN | MSigDB lists | GSE29949_CD8_NEG_DC_SPLEEN_VS_CD8_POS_DC_SPLEEN_DN | 187 | 48 | 17377 | 2626 |
WASF2,CCNC,NDUFS1,TRIP12,LAGE3,DHX8,GLUD1,COX4I1,SUPT7L,CSNK1A1,GGPS1,HNRNPA2B1,AHSA1,PDS5B,MARCH2,MAML1,GTF2H2,STRAP,HNRNPM,ELL2,NCK1,CREG1,CIC,ABCF2,ATP2C1,VDAC2,DCTD,BICD2,MEN1,ISG15,PRDX1,SRSF1,KIF2A,RPL37,PLD3,TPD52L2,ALDH3B1,HSPA4,LSM6,AXIN1,LRPPRC,NCLN,TAF12,RRS1,RUFY3,H3F3A,GCSH,IFI16 |
| 1.130e-04 | -9.09 | GSE37534_GW1929_VS_PIOGLITAZONE_TREATED_CD4_TCELL_PPARG1_FOXP3_TRANSDUCED_DN | MSigDB lists | GSE37534_GW1929_VS_PIOGLITAZONE_TREATED_CD4_TCELL_PPARG1_FOXP3_TRANSDUCED_DN | 187 | 48 | 17377 | 2626 |
SEPHS2,HSPH1,GCLM,ST13,RWDD1,FAM129A,MOGS,RRM1,C5orf30,ZNF267,BRIX1,BECN1,TMEM165,CUTC,SCYL2,FBXO5,ZNF804A,MAT2B,FKBP1A,ZDHHC13,SOCS6,STAT3,ABCC5,SRSF10,SAP30,RFC3,PRIM2,EID1,RB1CC1,CYP20A1,KIF15,CIRBP,GLO1,PCGF1,CHMP2B,SERP1,PLEKHF2,CYB5A,NECAP2,APPL2,TBPL1,NR2F2,RNF14,MAPK1,CCDC59,DYNC1LI2,ADNP2,EGLN1 |
| 1.130e-04 | -9.09 | GSE360_DC_VS_MAC_UP | MSigDB lists | GSE360_DC_VS_MAC_UP | 187 | 48 | 17377 | 2626 |
WSB2,ZNF207,USP7,TMED7,PHB2,SRGN,ENSA,TGOLN2,SUPT7L,PSMD9,RBM4,MAN1A1,ZNF804A,RAP1A,SMC3,INPP5A,SIAH1,RIMS3,APOOL,CPSF4,MOB1A,SPTSSA,TMED2,ATP6V1G1,SP3,BAK1,PTPN18,PPT1,ELL2,IDH3A,DNAJC9,PRPF3,ESYT1,MCFD2,API5,SF3A2,MAT2A,MKNK1,CACNB1,DDOST,TFE3,ACOX1,ACLY,MDH1,B4GALT3,TUBB,SMNDC1,PRPF4B |
| 1.130e-04 | -9.09 | GSE411_WT_VS_SOCS3_KO_MACROPHAGE_UP | MSigDB lists | GSE411_WT_VS_SOCS3_KO_MACROPHAGE_UP | 187 | 48 | 17377 | 2626 |
IMMT,C16orf87,CDK2AP2,CENPF,CUTA,KCTD17,UBE2I,PMVK,KCMF1,TFRC,PAPOLA,OIP5,CCP110,SUV39H2,UCHL5,SSBP3,GRSF1,PPP6C,CS,GEMIN6,MRPL21,MTPN,UBE2M,MSH6,GINS1,TDP1,MND1,TK1,HMGN5,ELL2,NSDHL,E2F3,CCDC34,ARHGEF12,PHF6,NEU1,HSPA1B,CBX3,FAS,DERL1,DSN1,NSMCE2,PTER,CENPT,WDR62,REEP4,OAZ1,CBX4 |
| 1.130e-04 | -9.09 | GSE39820_CTRL_VS_IL1B_IL6_CD4_TCELL_UP | MSigDB lists | GSE39820_CTRL_VS_IL1B_IL6_CD4_TCELL_UP | 187 | 48 | 17377 | 2626 |
HECA,CDC40,HNRNPAB,MRPS2,C1orf112,TCF3,ASAH1,BLM,CSNK1A1,PPP1R16B,SMC3,ATIC,RCSD1,SLC35B4,PIGG,DDX31,POLR1B,C12orf75,GPD1L,ZNF770,ARL5A,SOCS5,JMJD4,AMPD2,ERCC1,ELL2,TIMMDC1,DENND1B,NSDHL,ANKRD33B,AACS,TLK1,RRM2,MAT2A,KRIT1,ATP1A1,PTER,RBMX,FAM83D,ST3GAL2,CNOT6,ACTB,DNAJC30,RUFY3,OAZ1,CBX4,GPATCH4,PDCD4 |
| 1.130e-04 | -9.09 | GSE17186_NAIVE_VS_CD21LOW_TRANSITIONAL_BCELL_UP | MSigDB lists | GSE17186_NAIVE_VS_CD21LOW_TRANSITIONAL_BCELL_UP | 187 | 48 | 17377 | 2626 |
PIGM,SCAMP3,SUCLG1,CASP6,GNPDA1,ZFP91,GADD45G,TMEM109,C19orf25,FLOT1,AGPAT3,SIRT2,ARF1,IL21R,PSMD9,CDC73,RRP36,MAN1A1,PTPN2,KRI1,VAV1,RNF121,IRF4,NEK6,VMP1,ATG3,ETV6,FUT8,POP7,PDIA6,SYTL3,GPX4,AKT2,EMB,PGS1,JTB,SSR2,CYFIP2,KRTCAP2,ANKRD46,DAP3,TWSG1,NFIL3,PIAS2,CHMP4B,ATF6,MBOAT1,RBPJ |
| 1.130e-04 | -9.09 | GSE27786_LIN_NEG_VS_NKCELL_UP | MSigDB lists | GSE27786_LIN_NEG_VS_NKCELL_UP | 187 | 48 | 17377 | 2626 |
MRPL42,RRP15,SUCLG1,C1orf112,MRI1,NKD2,NENF,AP1B1,RCOR3,PITHD1,SRRT,PNO1,PRNP,FARSA,PDXP,STRBP,PHTF1,BDH1,ZDHHC13,FBXL7,KNTC1,MRPL48,RPRD1B,HDHD2,EIF3L,SGCE,TIMM8B,ACSL3,LDB1,NOL8,KCTD20,ADSL,CCDC34,MIER2,NUP155,CCNF,EIF3G,CLNS1A,DAP3,IARS2,H2AFX,DTX4,SMPD4,PPP5C,HRAS,LRP8,SAT2,IPO4 |
| 1.130e-04 | -9.09 | GSE17721_0.5H_VS_12H_CPG_BMDC_UP | MSigDB lists | GSE17721_0.5H_VS_12H_CPG_BMDC_UP | 187 | 48 | 17377 | 2626 |
SLC12A7,NDUFA5,NDUFB6,GNPDA1,CUTA,SMC6,GYG1,EBP,PRKD3,SMC3,GOT2,SH3BP1,ATG3,CRAT,SIVA1,PELO,ADCY9,CS,BCAP29,CORO1A,MAP3K14,SPTSSA,EEF1D,IMPA2,SRPK2,RPAP3,AGGF1,SEC61B,NSDHL,RAB7A,PPP1R21,LDHA,RRM2,TMEM147,SOX4,SLC50A1,ANKRD46,CLNS1A,RPA1,ALDH3B1,RPS14,MDH1,SRSF3,SCARB1,AP2S1,MYL12B,SLC25A39,RAB3IL1 |
| 1.130e-04 | -9.09 | GSE17301_CTRL_VS_48H_ACD3_ACD28_IFNA5_STIM_CD8_TCELL_UP | MSigDB lists | GSE17301_CTRL_VS_48H_ACD3_ACD28_IFNA5_STIM_CD8_TCELL_UP | 187 | 48 | 17377 | 2626 |
MIB2,TBC1D12,NCOR2,C9orf78,CDS2,REPS2,UBN1,GNPDA1,MECP2,MEF2A,KIF2C,SIRT2,MAN2B1,UBQLN2,APH1B,RAPGEF6,FAM8A1,PIP4K2A,MBD4,ANKRD26,CDKN2C,RABGAP1L,MEGF8,KIF22,TTC17,CTDSP2,TMEM9,ALDH9A1,SMC4,PLK1,MAPRE2,POLR3GL,CDCA2,ARID1A,SOCS7,MTMR3,VEZF1,TMEM127,SGSH,OSBPL11,TAB2,CEP55,EXOC4,CEBPG,CTSA,CCNB2,PURA,RNF114 |
| 1.131e-04 | -9.09 | GSE45365_CTRL_VS_MCMV_INFECTION_NK_CELL_DN | MSigDB lists | GSE45365_CTRL_VS_MCMV_INFECTION_NK_CELL_DN | 172 | 45 | 17377 | 2626 |
NDUFS1,TRIP12,WDYHV1,SF3B1,SESTD1,ACTR3,CHD1L,AP3M2,ASAH1,COMMD5,ZNF92,CYHR1,NDUFB9,TOP1MT,MYBL1,EEF1D,EBAG9,VPS13B,PHF20L1,POLR2L,FAM49B,COQ10B,RDH10,RPL8,MFNG,EIF2AK1,PRKRA,EIF3H,SH3GLB1,IWS1,XRCC5,DERL1,NEK1,PCM1,ATAD2,STK38,NSMCE2,STAT1,CBWD1,FAM126A,MRPL13,TERF1,RNF139,IFI16,NUMB |
| 1.131e-04 | -9.09 | CSE1L (chromosome segregation 1 like) | protein interactions | 1434 | 120 | 36 | 17029 | 2761 |
BCCIP,UNK,CYLD,SUZ12,UBXN1,WDR5,ATP6V1B2,BIRC2,CDC73,PABPC4,HUWE1,PPME1,CRY2,RP2,TCEA1,CDC5L,TXNL1,STAU1,HNRNPF,LDHA,NFATC2,BRCA1,MCM2,KIF18A,KPNA1,KPNA4,PLAA,TPP2,MAPK6,STAT1,ACAT1,KPNA2,FUS,PPP5C,CLN3,CDK2 |
| 1.133e-04 | -9.09 | GSE6092_UNSTIM_VS_IFNG_STIM_ENDOTHELIAL_CELL_DN | MSigDB lists | GSE6092_UNSTIM_VS_IFNG_STIM_ENDOTHELIAL_CELL_DN | 182 | 47 | 17377 | 2626 |
CORO7,MZT1,GMFG,UROD,ANKH,HEXB,KLF13,B4GALT1,EZH1,USP48,MAP1LC3B,CRLF3,ARID1B,CPNE3,FKBP1A,WDR44,METTL14,ARL6IP1,SRI,MSH2,CLDND1,CDC25B,CNN2,RNASEH2A,IFT46,VPS13B,PTPN18,TNFAIP3,PPT1,DNAJC9,PLEC,WBP1,PCGF1,ICAM2,KLF6,ANKRD46,ARHGAP15,EPB41,SUPT16H,CBX3,MYO1F,ADSS,INF2,CDKN2AIPNL,TAB2,NAA20,ABCA1 |
| 1.133e-04 | -9.09 | GSE14308_TH2_VS_TH17_UP | MSigDB lists | GSE14308_TH2_VS_TH17_UP | 182 | 47 | 17377 | 2626 |
CENPF,SLC29A1,EIF1B,PSMD9,ELMOD2,CAPN2,ERH,RAP1A,TNFAIP8,UCHL5,PPP1R8,PPP6C,CDC25B,SLC35A1,MTX2,ENPP4,BAK1,PPP1R18,TRIM8,KLF10,LAP3,ASPM,NSDHL,KAT7,NUDT4,DDX20,KRAS,GORASP2,CDC6,CDCA2,NUP155,EIF2A,ESYT1,SMC2,MCM2,AKAP1,STOML2,KIF18B,DGCR8,TOMM6,NSMCE2,EIF2D,MAPK6,YY1,RRS1,ESPL1,GCSH |
| 1.133e-04 | -9.09 | GSE17721_LPS_VS_GARDIQUIMOD_12H_BMDC_DN | MSigDB lists | GSE17721_LPS_VS_GARDIQUIMOD_12H_BMDC_DN | 182 | 47 | 17377 | 2626 |
NDUFV2,SMAP1,RPLP2,HJURP,SLC2A1,SNX15,SDC2,RRAGC,MEF2A,GTF3A,ADPGK,CNTROB,LACTB2,SLC20A1,TMEM165,TFRC,SEC11A,SLC31A1,ATP6V0B,PRKD3,GMEB1,SLC35B4,ANXA5,CABLES2,EEF1D,SPTAN1,SRPK2,ADAM17,PSRC1,PSPC1,TEX10,PCGF6,RPS10,DNAJC9,STK17B,MAK16,DHX15,RHOB,CYB5A,PON2,DAP3,HINT1,SLC16A1,SPCS3,NANP,UBE2C,RTN3 |
| 1.133e-04 | -9.09 | GSE14769_UNSTIM_VS_80MIN_LPS_BMDM_UP | MSigDB lists | GSE14769_UNSTIM_VS_80MIN_LPS_BMDM_UP | 182 | 47 | 17377 | 2626 |
PWWP2A,ZBED3,PRKAB1,CDS2,SYS1,HJURP,PHF23,MRPS2,RPS6KA1,AP3M2,NHLRC3,S1PR2,PITHD1,POLR3K,TRIM65,ATPAF1,MOAP1,CRKL,PPP1R3B,ANKLE1,ZBTB45,MEA1,YBX1,METTL9,ZNF770,FGFR1OP2,MED22,SNX8,POLR2I,MBLAC2,VHL,ERLIN1,MRPL43,ANAPC2,BMS1,RIT1,AURKB,MCFD2,BORA,BTBD1,MASTL,HHEX,NAGLU,ZRANB2,ZFP90,NANP,DYNC1LI2 |
| 1.133e-04 | -9.09 | GSE10240_CTRL_VS_IL22_STIM_PRIMARY_BRONCHIAL_EPITHELIAL_CELLS_DN | MSigDB lists | GSE10240_CTRL_VS_IL22_STIM_PRIMARY_BRONCHIAL_EPITHELIAL_CELLS_DN | 182 | 47 | 17377 | 2626 |
SLC30A9,TRIM41,PPP1R37,MAX,LUZP1,ADAM10,UBN1,HMGXB3,TAP1,WDTC1,RACGAP1,POMP,NANS,UBE4A,EZH1,ARF1,DAZAP2,HLA-A,WWP2,FKBP1A,VAV1,ATP6V0B,VASP,ASAP2,COQ4,RPL17,RAB35,PPCDC,ORAI1,ATG13,CLDND1,PTGES3,ZNF800,ELOF1,ULK3,HERPUD2,ANLN,CCNF,OSBPL11,GRIPAP1,MEGF9,COX5A,NCOA1,TAF12,ROCK1,RUFY3,NXT2 |
| 1.133e-04 | -9.09 | GSE2706_2H_VS_8H_R848_AND_LPS_STIM_DC_UP | MSigDB lists | GSE2706_2H_VS_8H_R848_AND_LPS_STIM_DC_UP | 182 | 47 | 17377 | 2626 |
MIF4GD,PIGN,KIAA0100,DHPS,ADAM10,TMX4,CERK,HAUS4,TWF2,PMVK,ELMOD2,CPNE3,CCDC28A,MAD2L2,NDUFS7,GSTK1,BANF1,SLC27A4,TTC3,CYC1,MRPL48,SGCB,TACC3,RNF5,HEMK1,GALC,KIAA0930,HEBP2,MPG,PTTG1IP,ICMT,SLC25A5,HAGH,RFC2,CBFB,MAT2A,MYO1F,CCDC14,QARS,EIF2D,CAMKMT,LPCAT4,ACAT1,COPS6,LTA4H,RTN3,AP2S1 |
| 1.133e-04 | -9.09 | GSE3982_MAC_VS_EFF_MEMORY_CD4_TCELL_UP | MSigDB lists | GSE3982_MAC_VS_EFF_MEMORY_CD4_TCELL_UP | 182 | 47 | 17377 | 2626 |
COX5B,NDUFV2,ZBTB10,NDUFS1,ST13,PLXNC1,REPS2,POLR2K,GNPDA1,TRIO,RAB23,BCL2L1,ZNF267,PSEN1,PIP5K1C,MCTS1,ZNF804A,SLC1A4,DPYSL2,PPME1,DNAAF2,ANXA5,MRPL40,TECR,AHCYL1,MLST8,SOCS5,GINS1,PPIF,TIMM8B,AGGF1,MTMR6,BRCA1,KIF11,APPL1,PICALM,PSMC4,SDHB,SEC61A1,CCDC6,PRDX3,TIMM17A,DBI,SEL1L,PDXK,RTN3,ACSF2 |
| 1.133e-04 | -9.09 | GSE22886_NAIVE_CD8_TCELL_VS_DC_UP | MSigDB lists | GSE22886_NAIVE_CD8_TCELL_VS_DC_UP | 182 | 47 | 17377 | 2626 |
RPS15,LIME1,TSC22D3,PCSK7,BTN3A1,IRF3,DNAJB1,ETS1,PIP4K2A,MOAP1,NRF1,MZT2A,MEX3C,BCL2,RPL19,CDC25B,OGG1,CAMK2G,TTPAL,NIPAL3,CYTH1,MAPRE2,NXT1,RPL35,AATF,TSPYL4,PBXIP1,LRBA,SLC16A7,RPL6,ITM2A,EZR,ADRB2,CYFIP2,ICAM2,STK17B,RPS9,MATR3,EIF3H,RPL36,PRIM1,MAGED2,STK38,EIF2D,MZT2B,CCDC59,C7orf26 |
| 1.133e-04 | -9.09 | GSE7400_CTRL_VS_CSF3_IN_VIVO_TREATED_PBMC_UP | MSigDB lists | GSE7400_CTRL_VS_CSF3_IN_VIVO_TREATED_PBMC_UP | 182 | 47 | 17377 | 2626 |
RPL15,HMGN3,ABHD14A,MAT2B,CSDE1,RRN3,UBE2Q2,ZNF420,ZNHIT6,BCL2,CISD2,PTGES3,OSTC,RBM15,YTHDC1,CCT2,EXOSC6,PRKDC,IDH3A,MBLAC2,ZMYND11,SCFD2,DDX20,BMS1,BCLAF1,ESYT1,PRKRA,ODC1,MTR,MATR3,TWISTNB,CLNS1A,NMT2,EIF3K,NSA2,FBXO21,BOLA3,HNRNPH3,CAPN7,WDR4,LRPPRC,SRSF3,RRS1,TATDN1,C11orf1,MRPL3,GPATCH4 |
| 1.133e-04 | -9.09 | GSE27786_LIN_NEG_VS_NKCELL_DN | MSigDB lists | GSE27786_LIN_NEG_VS_NKCELL_DN | 182 | 47 | 17377 | 2626 |
OTUD5,ASH1L,PDCD6IP,GGNBP2,CDC40,TM9SF4,DHPS,RAF1,CHKB,AGFG1,MYO9B,EZH1,ETS1,GIT2,DDRGK1,TMCC3,ATP6V0B,XPA,PPCDC,ARHGEF2,ATF2,PHKG2,MYO5A,SAP30,VPS13B,TRIM8,TACC1,C16orf72,PPP1R21,GBA,RPL38,ASB13,PTTG1IP,TFEB,PFDN5,JAK1,CHD3,MFAP1,HPS5,CTBS,KBTBD7,STAT1,DNAJC17,PSAP,FAU,USF2,HIGD2A |
| 1.133e-04 | -9.09 | GSE13738_RESTING_VS_BYSTANDER_ACTIVATED_CD4_TCELL_DN | MSigDB lists | GSE13738_RESTING_VS_BYSTANDER_ACTIVATED_CD4_TCELL_DN | 182 | 47 | 17377 | 2626 |
KIF3B,MRPL42,TM9SF4,DYNLL1,TOR3A,PTTG1,PLAGL2,BCL2L1,IKBIP,PPP1R16B,STAM,TFRC,EBP,BCAT2,MCTS1,CDK5,IRF4,MLX,RALB,CENPJ,MBD2,TTC9C,CLDND1,TAGLN2,LRRC59,C12orf75,MYO5A,SAP30,COPS8,ELOVL5,CYFIP1,PPP1R18,SEC61B,TCTEX1D2,BIRC3,LYRM1,TXNL4A,SH3BP5,SLCO4A1,ITPRIPL1,UEVLD,DBI,C4orf46,COX5A,PKD2,LRP8,BYSL |
| 1.133e-04 | -9.09 | GSE14908_ATOPIC_VS_NONATOPIC_PATIENT_RESTING_CD4_TCELL_UP | MSigDB lists | GSE14908_ATOPIC_VS_NONATOPIC_PATIENT_RESTING_CD4_TCELL_UP | 182 | 47 | 17377 | 2626 |
PRKAB1,HECA,GGNBP2,MECP2,FAM129A,UBXN1,RAC1,COPE,TMX4,AP3M2,GLUD1,TMED3,MAPK14,PIP4K2A,PARK7,RHBDD1,MXD1,PHC2,RAB21,NRF1,RAB8A,VASP,LRRC8D,SRI,CNPY4,TTC3,CLDND1,TERF2,PPP1R18,PBXIP1,GALC,C16orf72,ASB13,KRTCAP2,NDRG3,SH3GLB1,NMT2,KEAP1,WAS,UAP1,GOLGA7,CERS6,STAT1,ZDHHC7,PSAP,IDH3B,TMEM14A |
| 1.133e-04 | -9.09 | GSE40666_UNTREATED_VS_IFNA_STIM_EFFECTOR_CD8_TCELL_90MIN_UP | MSigDB lists | GSE40666_UNTREATED_VS_IFNA_STIM_EFFECTOR_CD8_TCELL_90MIN_UP | 182 | 47 | 17377 | 2626 |
CORO7,TRERF1,GGA1,TAP1,TKT,KLHL18,PTP4A3,PPP1R16B,CFLAR,CAPN2,GSTK1,NEK6,ZNF335,CS,MDFIC,TAGLN2,MVP,CARM1,VOPP1,TRIM8,WDR1,SEPT8,WDR82,MYO1F,TFEB,FAS,PI4K2A,TRIM47,KEAP1,ATP1A1,AHNAK,RBM47,HIPK2,TFDP1,ITGB1,NLRC5,CAB39,CTSA,ASNA1,KPNA2,SCARB1,ZMIZ1,GEN1,YWHAH,AP2S1,ACSF2,GEMIN7 |
| 1.133e-04 | -9.09 | GSE31082_DN_VS_CD4_SP_THYMOCYTE_UP | MSigDB lists | GSE31082_DN_VS_CD4_SP_THYMOCYTE_UP | 177 | 46 | 17377 | 2626 |
DNAJC2,C9orf78,PHB2,WDTC1,PCBP1,ARL6IP6,SUB1,SMC3,AHCTF1,CCP110,CBWD2,BRPF3,NDUFB4,FBXO7,FEM1B,CENPM,PRADC1,ERI3,GPD1L,PPA1,HNRNPM,CSTF1,GINS1,ACSL5,PHF10,PSRC1,DHX29,POLR2D,EXOSC9,DCUN1D5,RAB1A,AP4E1,TXNL4A,EIF3A,ADSS,EIF3K,CDKN2AIPNL,HINT1,CDCA7L,PTAR1,RWDD4,NAA20,TFDP2,NMD3,C7orf26,PTOV1 |
| 1.133e-04 | -9.09 | GSE27786_NKCELL_VS_ERYTHROBLAST_UP | MSigDB lists | GSE27786_NKCELL_VS_ERYTHROBLAST_UP | 177 | 46 | 17377 | 2626 |
SEPHS2,TCF12,MRPL42,PHF23,TBC1D13,HMGN3,NHLRC3,MYO9B,ZADH2,ANKIB1,EXT2,RRP36,NDUFS4,RBM17,ZNF260,PPCDC,ZDHHC13,RPN2,RPL22L1,PPA1,HTRA2,TRIM14,CCAR1,RLIM,DCTN1,UBQLN4,TSPYL4,CRNKL1,WDR82,ABHD11,ARID1A,EIF2A,RHOT1,PTTG1IP,ASB13,ICMT,DHX15,DHX57,GOLGA4,ZC3H7B,CDCA7L,DNAJC17,ATE1,ZFP90,CPEB2,NRBP1 |
| 1.133e-04 | -9.09 | GSE9988_ANTI_TREM1_VS_LOW_LPS_MONOCYTE_UP | MSigDB lists | GSE9988_ANTI_TREM1_VS_LOW_LPS_MONOCYTE_UP | 177 | 46 | 17377 | 2626 |
KCTD7,GNPDA1,PHF23,HEXB,RRAGC,ATP6V1B2,MAP1LC3B,BCAP31,ANKRD28,MOAP1,DTL,SNUPN,SLC1A4,RNASEK,FBXO7,ZCCHC2,ARL6IP1,NAA50,BRI3,FNIP2,TMBIM1,ATP6V1G1,SNX8,TCTEX1D2,LONRF3,AMD1,ACSL3,CAMSAP1,MAP4K3,VKORC1,RHOB,NEU1,PI4K2A,SH3BP5,SCARB2,SLCO4A1,PEX5,ATP6V1D,PPP2R5A,SLC38A7,LIMK1,CORO1C,CENPBD1,WDR91,NRBP1,ZC3HC1 |
| 1.134e-04 | -9.08 | GO_PROTEIN_N_LINKED_GLYCOSYLATION | MSigDB lists | GO_PROTEIN_N_LINKED_GLYCOSYLATION | 73 | 24 | 17377 | 2626 |
DPM1,GORASP1,PRKCSH,MAN1B1,MOGS,B4GALT1,SYVN1,MCFD2,EDEM2,TMEM165,MAN1A1,MAN2A2,RPN1,MAGT1,DDOST,STT3A,DAD1,FUT8,RPN2,ST3GAL2,OSTC,LMAN1,ST8SIA2,MGAT5 |
| 1.137e-04 | -9.08 | RPL38 (ribosomal protein L38) | protein interactions | 6169 | 129 | 38 | 17029 | 2761 |
RPS2,RPLP2,RPL15,CUL1,HAUS2,RPL11,RPL23A,NDUFA2,IARS,PTEN,RPL17,DUT,AHSA1,RRBP1,MRPL34,RPL19,RPL29,RPL35,CUL3,RPL8,RPL6,RPS10,NDUFA7,MCM2,RPL27A,RPS9,RPSA,CAND1,RPL36,TFE3,RPS14,RPLP1,RBMS1,RUVBL2,COPS6,EHD4,RPS26,ZC3HC1 |
| 1.137e-04 | -9.08 | PSMC4 (proteasome 26S subunit, ATPase 4) | protein interactions | 5704 | 129 | 38 | 17029 | 2761 |
RORB,KIAA0100,ZCCHC8,DCTN2,PSMD9,UBLCP1,RAD23A,PTPN2,HERC3,PSMD2,PSMD1,PSMA6,HUWE1,CENPJ,UCHL5,AHSA1,RAD23B,YBX1,CRY2,FTSJ3,CDC5L,PSMA8,CUL3,PSMB7,PSMA1,SMC2,BRCA1,MCFD2,PSMB9,PSMB3,PFDN5,PSMD3,PSMD8,RBBP4,MAP3K5,SMURF1,ECPAS,PSMC1 |
| 1.145e-04 | -9.08 | IDH2 (isocitrate dehydrogenase (NADP(+)) 2, mitochondrial) | protein interactions | 3418 | 34 | 15 | 17029 | 2761 |
SLC39A9,ZNF207,PA2G4,IDH3A,ZNF746,KBTBD7,MRPL12,ANXA5,GPI,SND1,ADRB2,IDH3B,CDK2,KCMF1,GLMP |
| 1.145e-04 | -9.08 | Rprd1b (regulation of nuclear pre-mRNA domain containing 1B) | protein interactions | 70470 | 34 | 15 | 17029 | 2761 |
PAF1,POLR2I,RPRD1A,MCM10,POLR2G,POLR2J,POLR2D,CTR9,HDGFL2,CDC73,POLR2A,AKAP1,ELOF1,IWS1,SUPT16H |
| 1.146e-04 | -9.07 | HAUS6 (HAUS augmin like complex subunit 6) | protein interactions | 54801 | 81 | 27 | 17029 | 2761 |
CCDC93,MAX,RPRD1A,RCOR1,NUF2,HAUS4,PSMD9,HAUS2,GIT2,APP,HMG20A,HAUS8,OIP5,CEP104,PCM1,CDC16,CCP110,GRIPAP1,CENPJ,RABGAP1L,ODF2,ARNTL,CEP63,SASS6,POC5,DCTN1,NIPSNAP1 |
| 1.146e-04 | -9.07 | human chr16p13.3 | chromosome location | human chr16p13.3 | 238 | 45 | 26185 | 2809 |
CORO7,RPS2,ABCA3,TRAF7,TSC2,UBN1,FLYWCH2,CHTF18,PIGQ,CDIP1,HCFC1R1,UBE2I,POLR3K,TFAP4,SNRNP25,TEDC2,CLUAP1,GLIS2,ADCY9,ZNF200,METTL26,TMEM8A,SPSB3,MLST8,NAGPA,PDPK1,TELO2,ZNF500,RNPS1,AMDHD2,PKMYT1,CCNF,MPG,RHOT2,HAGH,LUC7L,GFER,ZNF174,AXIN1,TBL3,HAGHL,ATP6V0C,ZNF75A,ZNF598,NAA60 |
| 1.149e-04 | -9.07 | REACTOME_AUTODEGRADATION_OF_CDH1_BY_CDH1_APC_C | MSigDB lists | REACTOME_AUTODEGRADATION_OF_CDH1_BY_CDH1_APC_C | 56 | 20 | 17377 | 2626 |
PSMB7,PSMA1,ANAPC2,CDC23,PSMB9,PSMD9,PSMB3,PSMC4,PSMD2,PSMA6,PSMD1,CDC16,CDC27,RPS27A,PSMD3,PSMD8,ANAPC7,UBE2C,PSMC1,ANAPC4 |
| 1.155e-04 | -9.07 | GPBP1L1 (GC-rich promoter binding protein 1 like 1) | protein interactions | 60313 | 45 | 18 | 17029 | 2761 |
AMPD2,SNRNP200,EWSR1,PIP4K2C,AP1B1,CNOT11,PIP4K2A,EIF3H,EIF3A,PLEKHF2,CNOT9,QRSL1,KANSL2,ECD,CNOT6L,PDCD2L,DCAF5,AP2S1 |
| 1.155e-04 | -9.07 | PINX1 (PIN2 (TERF1) interacting telomerase inhibitor 1) | protein interactions | 54984 | 45 | 18 | 17029 | 2761 |
TXN,GABPA,WDYHV1,RPS10,RPL8,GTPBP4,FXR1,APP,DHX15,PABPC4,RPL23A,DGCR8,AHCY,SNRNP70,FBL,PPP2R2D,TERF1,PABPC1 |
| 1.155e-04 | -9.07 | OAT (ornithine aminotransferase) | protein interactions | 4942 | 45 | 18 | 17029 | 2761 |
COX15,UBQLN4,STAU1,EZR,PITPNB,ADRB2,OAT,PARK7,ADSS,HUWE1,AKR1B1,CTSA,PDXK,DMWD,FUS,ATF2,CDK2,NUDT3 |
| 1.155e-04 | -9.07 | MBD2 (methyl-CpG binding domain protein 2) | protein interactions | 8932 | 45 | 18 | 17029 | 2761 |
PHF20L1,MTA2,DHX9,LAMTOR3,MBD3,HMG20A,POLR2A,TFAP4,CHD3,MBD2,MTA1,CDCA5,RBPJ,RBBP4,DNMT1,HDAC2,IFI16,TACC3 |
| 1.163e-04 | -9.06 | GTGCAAT,MIR-25,MIR-32,MIR-92,MIR-363,MIR-367 | MSigDB lists | GTGCAAT,MIR-25,MIR-32,MIR-92,MIR-363,MIR-367 | 296 | 69 | 17377 | 2626 |
CCNC,RAB14,PPCS,ATXN3,TMEM184B,UGP2,LUZP1,GPBP1L1,ADAM10,C5orf30,UBE2Z,KLHL18,MYH9,SNN,BCAT2,MOAP1,NRF1,ATP2A2,PPP1R12C,PDS5B,JOSD1,BAZ2A,BTG2,E2F3,MCL1,MEF2D,SOX4,HERPUD2,TRAM2,RBM47,CLK3,GOLGA8A,MYO18A,RNF38,OGT,ANP32E,SPRYD4,TFDP2,DNAJC30,PPP1R12A,TRIO,RAB23,SDC2,ARID1B,DNAJB9,WWP2,WRNIP1,PIP5K1C,KIF5B,FOXN2,PIKFYVE,CREB1,SOCS5,MORC3,DCAF6,POLK,CIC,FXR1,APPL1,BSDC1,TSC1,GOLGA4,SERTAD2,CDCA7L,PITPNA,PGAM1,CHMP7,TOB1,CPEB2 |
| 1.165e-04 | -9.06 | regulation of cellular pH | biological process | GO:0030641 | 95 | 29 | 17256 | 2622 |
CLCN3,PPT1,TM9SF4,RAB7A,GPR89A,SLC26A6,ATP6V0A1,SLC4A2,ATP5F1B,ATP6V1B2,TMEM165,MAPK3,ATP6V0B,ATP6V1D,CLIC4,ATP6V0A2,BCL2,ATP6V0C,SLC26A2,ATP6V1C1,CLN3,MAPK1,CLN6,ATP6V0D1,ATP6V0E1,GPR89B,SNAPIN,ATP6V1G1,CHP1 |
| 1.173e-04 | -9.05 | DYNLL1 (dynein light chain LC8-type 1) | protein interactions | 8655 | 223 | 58 | 17029 | 2761 |
COX15,RPS2,DYNLL1,RAE1,RAF1,STRN4,XIAP,CUL1,GLUD1,BCL2L1,RGS2,CSNK1A1,PRKACA,BECN1,PCBP1,SPAG5,DNAJB9,NRF1,NEK6,MTA1,RAB4A,CS,DNM2,BCL2,MAST2,DNMT1,PABPC1,CFL1,MYO5A,MORC3,DCTN1,MOB4,TCTEX1D2,FOPNL,NEK7,ZMYND11,TLK1,LDHA,NADK2,NLN,MCM2,MTR,FKBP3,RPSA,ASF1B,ZMYM3,CACNB1,PCM1,ZHX1,FAM83D,ACTB,FAU,GLCCI1,PFKP,DYNC1LI2,IFI16,TUBB,PARD3 |
| 1.173e-04 | -9.05 | RACK1 (receptor for activated C kinase 1) | protein interactions | 10399 | 223 | 58 | 17029 | 2761 |
UNK,RPS2,CYLD,CHERP,AGTRAP,SUZ12,DYNLL1,HABP4,RPL15,CUL1,ITGB5,PCBP1,WWP2,GOLM1,RB1,HUWE1,AHSA1,ZNF746,FEM1B,FBXW2,RPL19,TARDBP,MCPH1,STAT3,PABPC1,PCBP2,STAU1,RHOA,VHL,MKI67,CUL3,SREK1,AURKB,BRCA1,ADRB2,PLEC,MCM2,RPL27A,RPS9,RPSA,ISG15,ARF4,CAND1,DERL1,EIF3K,SYNCRIP,JAK1,MAPK6,STAT1,ITGB1,CAB39,WDR76,CDK2,CD81,DYNC1LI2,TUBB,PTOV1,FUBP1 |
| 1.175e-04 | -9.05 | BROMODOMAIN_2 | prosite domains | PS50014 | 39 | 15 | 12060 | 1670 |
ASH1L,BRD4,ATAD2,BRWD1,KAT2A,BRD2,BRPF3,BAZ2A,ZMYND11,BRD7,SMARCA4,BAZ1B,PBRM1,BRD9,BRWD3 |
| 1.179e-04 | -9.05 | carbohydrate derivative biosynthetic process | biological process | GO:1901137 | 613 | 127 | 17256 | 2622 |
ADA2,PIGM,PPCS,GXYLT1,AGRN,GNPNAT1,UGP2,GNPDA1,PIGQ,UCK2,MOGS,UCK1,RXYLT1,NANS,SLC35B2,ADPGK,ATP5PF,EXT2,TET3,DUT,ADCY9,PPCDC,UPRT,RPN2,SLC26A2,LMAN1,SLC35C2,MGAT5,PDCL3,ABCC5,ADCY7,PGAP2,TMEM115,DPM1,ATP6V0A1,RRM2,OGDH,AMDHD2,GALNT7,MCFD2,KRTCAP2,SERP1,STOML2,ALG3,MAN2A2,DDOST,STT3A,GUCY1B1,OGT,CANT1,DHTKD1,ST3GAL2,GALNT10,DHFR2,B4GALT3,CHPF2,PFKP,B4GALT2,GALK1,COX5B,PIGN,GORASP1,B4GALT5,GNE,RRM1,TRAK1,TKT,SDC2,B4GALT1,SDF2L1,ATP5F1B,B4GALT4,PSEN1,TMEM165,POFUT1,HDDC2,MAN1A1,RPN1,C1GALT1,NUS1,GART,PYURF,ATIC,DAD1,FUT8,CTPS1,PIGG,ATP6V0A2,CYC1,OSTC,ST8SIA2,AMPD2,TGFB1,B3GALT6,NAGPA,TK1,GUK1,PIGT,TSTA3,MAN1B1,AMD1,MFNG,LDHA,ADSL,DCTD,SYVN1,PKM,ATP5MF,ADSS,GALNT2,MAGT1,UAP1,GOLGA2,ATP5MC3,DCK,PRPS2,TYW5,TBPL1,IMPDH1,ACAT1,GPI,ATP5F1A,NANP,PLOD3,NIPSNAP2,HEXA,PGAM1 |
| 1.181e-04 | -9.04 | KEGG_BLADDER_CANCER | MSigDB lists | KEGG_BLADDER_CANCER | 40 | 16 | 17377 | 2626 |
RB1,FGFR3,MDM2,NRAS,RAF1,DAPK1,E2F1,E2F3,KRAS,E2F2,MAPK1,MAP2K2,HRAS,CDKN2A,DAPK3,MAPK3 |
| 1.181e-04 | -9.04 | GO_EARLY_ENDOSOME | MSigDB lists | GO_EARLY_ENDOSOME | 275 | 65 | 17377 | 2626 |
WASF2,MIB2,CCDC93,RAB14,SNX27,CYTIP,ANKRD27,RAC1,PTP4A3,NIPA2,RUFY1,STAM,KIFC1,RAB21,RAP1A,SIAH1,MTMR4,RABGAP1L,CORO1A,F2R,SNX8,CLCN3,AKT2,RAB1A,RAB5B,RAB22A,PLEKHF2,GRIPAP1,VPS26B,VPS4A,CLN3,MAPK1,NUMB,HLA-E,FLOT1,TRAK1,TMEM165,HLA-A,ST8SIA2,PIKFYVE,ATP6V0D1,MYO5A,SNX2,USP10,KCNQ1,ADRB2,APPL1,MAP2K2,RHOB,PI4K2A,MAPK3,DERL1,HLA-B,NUCB1,TMEM127,HGS,PRDX3,APPL2,SIAH2,PML,EHD4,RPS6KC1,VPS29,ALS2,NIPA1 |
| 1.182e-04 | -9.04 | REACTOME_REGULATION_OF_MRNA_STABILITY_BY_PROTEINS_THAT_BIND_AU_RICH_ELEMENTS | MSigDB lists | REACTOME_REGULATION_OF_MRNA_STABILITY_BY_PROTEINS_THAT_BIND_AU_RICH_ELEMENTS | 82 | 26 | 17377 | 2626 |
EXOSC6,PSMA8,PSMB7,PSMA1,EXOSC9,MAPK14,PSMB9,PSMD9,PARN,PSMB3,HSPA1B,PSMC4,PSMD2,PSMA6,EXOSC7,PSMD1,RPS27A,PSMD8,PSMD3,EXOSC1,KHSRP,ANP32A,DCP1A,YWHAZ,PSMC1,PABPC1 |
| 1.189e-04 | -9.04 | V$E2F_Q6_01 | MSigDB lists | V$E2F_Q6_01 | 223 | 55 | 17377 | 2626 |
H2AFZ,REPS2,ZCCHC8,RAB11B,PRKCSH,RMI2,CTCF,ORC1,STMN1,FBXO5,C14orf119,FANCL,PCNA,SMC3,INTS7,DPYSL2,MEA1,PDS5B,TNPO2,PCYT2,CITED2,ANKHD1,DNMT1,ARID4A,LUC7L2,EIF5A,CLPTM1,PPP1R9B,NASP,PRKDC,E2F3,SREK1,RRM2,CDC6,SMC2,PKMYT1,NUTF2,MCM2,MAT2A,SRSF1,HMGN2,PRIM1,DDX17,ATAD2,RBL1,DCK,ZNF367,NDUFA11,E2F1,ATE1,ANP32E,RBPJ,BTBD10,RBBP4,SASS6 |
| 1.192e-04 | -9.03 | mTOR signaling pathway | Pathway Interaction DB | mtor_4pathway | 60 | 24 | 2226 | 426 |
PDPK1,RHOA,TSC2,RB1CC1,RAF1,RPS6KA1,RAC1,CYCS,AKT1S1,MAP2K2,RHEB,MAPK3,EEF2K,TSC1,RRN3,PML,ATG13,YWHAZ,YY1,YWHAH,MAPK1,CDK2,PDCD4,MLST8 |
| 1.192e-04 | -9.03 | GO_OXIDOREDUCTASE_ACTIVITY_ACTING_ON_NAD_P_H_QUINONE_OR_SIMILAR_COMPOUND_AS_ACCEPTOR | MSigDB lists | GO_OXIDOREDUCTASE_ACTIVITY_ACTING_ON_NAD_P_H_QUINONE_OR_SIMILAR_COMPOUND_AS_ACCEPTOR | 52 | 19 | 17377 | 2626 |
NDUFA5,NDUFV2,NDUFS1,NDUFB6,NQO1,NDUFAF2,NQO2,NDUFA4,NDUFA7,NDUFB1,NDUFS7,NDUFS4,NDUFV1,NDUFA2,NDUFB4,NDUFB9,NDUFS8,NDUFS5,NDUFA3 |
| 1.194e-04 | -9.03 | WEI_MIR34A_TARGETS | MSigDB lists | WEI_MIR34A_TARGETS | 138 | 38 | 17377 | 2626 |
ZNF207,PKP4,GOLPH3L,TMEM184B,SNX15,FAM76A,DNAJC24,ARGLU1,PMF1,ASXL2,PPP1R16B,ATPAF1,TMCC3,GTF2F1,JAKMIP1,NUP210,SAR1A,SLC44A1,FUT8,NAA50,ANXA5,NAGPA,BAZ2A,HMGN4,MBLAC2,ERLIN1,GMFB,GORASP2,MTMR12,PNPLA8,GALNT7,TTC33,DDX17,EPB41,TFDP2,TSEN15,SMAD4,S100PBP |
| 1.195e-04 | -9.03 | PPP2R1B (protein phosphatase 2 scaffold subunit Abeta) | protein interactions | 5519 | 107 | 33 | 17029 | 2761 |
IER2,FGFR1OP,PRKAA1,DNAAF5,SIKE1,FOXO3,RAB11A,PARK7,RPN1,PDCD10,ARPC5,INTS1,PPP4R1,DAPK1,ANXA5,CRY2,ZRANB1,STAT3,FGFR1OP2,MOB4,TNFAIP3,RAB7A,ARPC1A,PRDX1,PPP2CA,RAB18,CDCA4,PPP2R5A,PTPDC1,ACADM,PPP2R2D,USP53,PDCD4 |
| 1.195e-04 | -9.03 | PRPF6 (pre-mRNA processing factor 6) | protein interactions | 24148 | 107 | 33 | 17029 | 2761 |
SART1,RAF1,USP39,THRAP3,SNRPD3,LMNA,RPA2,MEX3C,EIF4A3,ZNF746,EFTUD2,ZNF326,HNRNPM,LUC7L2,CDC5L,PRPF19,SNRNP200,RBM42,SMU1,RNPS1,RPS24,SRSF5,BRCA1,PRPF3,TXNL4A,SF3A2,SNRPA,SUPT16H,DDX23,RPA1,PRPF4,SNRPG,PRPF4B |
| 1.197e-04 | -9.03 | SON (SON DNA binding protein) | protein interactions | 6651 | 77 | 26 | 17029 | 2761 |
SRSF11,NDUFAF2,VHL,SUZ12,SF3B1,TCF3,SF3B6,DHX9,ILF3,USP39,PRPF3,DIDO1,SRSF5,SEPT7,RBM17,TRIM26,EIF4A3,SAFB,BUD31,KIFAP3,IFI16,HNRNPM,SRPK2,CDC5L,PRPF19,HP1BP3 |
| 1.208e-04 | -9.02 | CKAP5 (cytoskeleton associated protein 5) | protein interactions | 9793 | 94 | 30 | 17029 | 2761 |
INTS2,UNK,MAPRE1,HARS,TACC1,DHX29,TRMT6,XIAP,SDC2,LDHA,BRCA1,HAUS2,USP21,RPA1,AKAP1,DOT1L,TFAP4,RPA2,KLHL20,INTS7,AHSA1,EIF2D,DDX31,TAP2,ACAD8,H3F3A,IFI16,TACC3,LDHB,CDC5L |
| 1.210e-04 | -9.02 | cellular nitrogen compound catabolic process | biological process | GO:0044270 | 457 | 99 | 17256 | 2622 |
ADA2,RPLP2,RBM8A,ADPGK,SND1,PAIP1,PABPC4,EDC3,RPL23A,MBD4,RPL11,TET3,CSDE1,EIF4A3,METTL14,DUT,EXOSC1,RNASEH2A,OGG1,ENPP4,RPL29,RPL35,EXOSC6,POLR2G,RPL38,POLR2D,RNPS1,OGDH,RPS9,RPSA,RPL37,PPP2CA,HINT1,RPS27A,LSM6,RPS14,NT5C3B,RPLP1,DHTKD1,SMG9,NUDT11,RPS26,PFKP,GALK1,RPS15,RPS2,GSPT2,TATDN3,RPL15,PM20D2,THRAP3,PARN,CNOT11,METTL3,CNOT3,TUT4,NEIL2,PRPF18,PDXP,EXOSC7,RPL17,PPP1R8,PELO,DCP1A,RPL19,UPF2,AHCY,CNOT6L,PABPC1,SAMD4B,RNASEH2C,TRIR,NUDT4,RPL6,LDHA,RPL8,RPS10,RPS24,EXOSC9,PKM,PDE3B,RPL27A,PATL1,RPL36,HSPA1B,CNOT9,KPNA1,UPF1,RPL32,TATDN2,KHSRP,CNOT6,HMGB2,DNPH1,DDX5,GPI,TATDN1,PGAM1,NUDT3 |
| 1.222e-04 | -9.01 | WWP2 (WW domain containing E3 ubiquitin protein ligase 2) | protein interactions | 11060 | 185 | 50 | 17029 | 2761 |
UBE2D3,USP7,PDCD6IP,EWSR1,SCAMP3,DHX9,OLA1,CUL1,ARF1,WDR5,UBE2I,TUBGCP2,PAIP1,WWP2,CSDE1,FARSA,VASP,PCNA,BABAM2,EIF4A3,PTEN,ABRAXAS2,TP53BP2,STRAP,PABPC1,DVL2,CFL1,RPAP3,CCT2,DPM1,PRRC2A,WBP2,HNRNPF,POLR2D,WIPF1,DNAJA1,DIDO1,WBP1,PKM,SLC25A5,EIF3A,POLR2A,DDX17,SMAD2,SYNCRIP,PPM1G,ARRDC1,DDX5,DVL1,ATP5F1A |
| 1.222e-04 | -9.01 | ATM (ATM serine/threonine kinase) | protein interactions | 472 | 185 | 50 | 17029 | 2761 |
NSD3,AP1B1,BLM,MAPK14,FOXO3,HLA-A,FANCI,ZER1,RPA2,CDKN2C,MDM2,SMC3,KDM2A,HUWE1,XPA,MSH2,AP2B1,CREB1,ATF2,MCPH1,TIPARP,MSH6,TERF2,USP34,TELO2,TDP1,AATF,VHL,PRKDC,UTP15,CDC6,BRCA1,DCLRE1C,MCM2,TRIM28,RHEB,POLR2A,RPA1,XRCC5,MTMR3,PEX5,UPF1,RBM47,H2AFX,E2F1,STK11,CHEK2,TERF1,ATMIN,CSNK1D |
| 1.225e-04 | -9.01 | XBP1(S) activates chaperone genes | REACTOME pathways | R-HSA-381038 | 56 | 21 | 10287 | 1696 |
SEC61B,ADD1,SEC61G,CXXC1,SYVN1,SERP1,LMNA,DNAJB9,SSR1,YIF1A,SEC31A,SHC1,SEC61A1,TATDN2,ASNA1,MYDGF,PDIA6,CTDSP2,ATP6V0D1,PREB,DCTN1 |
| 1.225e-04 | -9.01 | sarcoma | COSMIC cancer mutations | sarcoma | 57 | 20 | 17385 | 2587 |
EWSR1,NRAS,SF3B1,RAC1,KRAS,EML4,GNAS,CDKN2C,FGFR3,RB1,PTEN,AXIN1,JAZF1,ETV6,PTPN11,FUS,H3F3A,STAT3,HRAS,CDKN2A |
| 1.228e-04 | -9.01 | protein kinase binding | molecular function | GO:0019901 | 618 | 129 | 17224 | 2647 |
FGFR1OP,ADAM10,PRKCSH,CCNB1,BECN1,MAPK14,CDKN2C,CALM2,USF1,PCNA,NEK6,CDC42,FIZ1,PIK3R2,PPP1R12C,CDC25B,CDC37,PTPRK,PLK1,RHOBTB3,NCK1,EZR,RHEB,WAS,AXIN1,ADAM9,ACTB,CHEK2,DVL1,SMAD1,ARRB2,SLC12A7,MAPRE1,PPP1R12A,RHOC,MEF2A,TOP2B,CDK13,RACGAP1,PARN,KIF13B,HDAC7,FBXO7,MSH2,MAML1,MVP,SLC12A2,SOCS5,MAPKAPK3,RB1CC1,ACSL3,APPL1,RHOB,FNTA,GOLGA2,NSF,DUSP3,CSK,QARS,FAM83D,YWHAZ,MAP3K5,PDLIM5,TOB1,CDKN2A,RHOG,CYLD,FOXM1,RAF1,RAC1,TPX2,BCL2L1,DAZAP2,AP1B1,GLRX3,TWF2,PRKACA,CPNE3,CCNA2,SHC1,KIF14,TBC1D14,PPME1,PIN1,CDKN1B,MAVS,ATF2,CDK12,DVL2,DCTN1,VDAC1,ATP1A1,HINT1,STK38,TICAM1,ZC3HC1,DCTN2,TCF3,DBF4,SIKE1,FOXO3,MAD2L2,FBXO5,CCNK,PTPN2,FGFR3,PDCD10,PTEN,CENPJ,PRC1,PTPN11,H2AFY,ATG13,STAT3,PDPK1,TELO2,RHOA,STRIP1,JTB,PRKAR1B,RFFL,KCNQ1,BORA,KIF11,PDE3B,PRDX3,MAPK6,PGAM1,FAF1 |
| 1.233e-04 | -9.00 | CIAPIN1 (cytokine induced apoptosis inhibitor 1) | protein interactions | 57019 | 49 | 19 | 17029 | 2761 |
KARS,LARS,EWSR1,PPP1R2,RBM8A,BOLA1,ATP6V1B2,GLRX3,RAB5B,EPRS,ATP6V1D,IARS,UCHL5,MSH2,CAPZA1,STAT1,NMD3,SSSCA1,ALDH9A1 |
| 1.233e-04 | -9.00 | NCBP3 (nuclear cap binding subunit 3) | protein interactions | 55421 | 49 | 19 | 17029 | 2761 |
WSB2,FYTTD1,NIFK,SARNP,TMEM184B,THOC1,SUZ12,GSPT2,RPL6,CUL3,PLEC,DDX39A,APP,PNO1,HNRNPH3,IFI16,LUC7L2,SRPK2,HP1BP3 |
| 1.233e-04 | -9.00 | TMED2 (transmembrane p24 trafficking protein 2) | protein interactions | 10959 | 49 | 19 | 17029 | 2761 |
TMED7,COPA,TM9SF4,GORASP1,AKT2,RPS10,GORASP2,TMED3,ARF1,USP22,RAB1A,SDHB,ATP1A1,GOLGA2,TMED10,PTAR1,DNAJC30,LMAN1,RPS26 |
| 1.236e-04 | -9.00 | GO_ORGANOPHOSPHATE_METABOLIC_PROCESS | MSigDB lists | GO_ORGANOPHOSPHATE_METABOLIC_PROCESS | 818 | 162 | 17377 | 2626 |
COX15,PIGM,PPCS,NDUFB6,UQCR10,PIGQ,HEXB,AGPAT1,CDIPT,MBD4,CALM2,IMPAD1,PIK3R2,SLC44A1,PPCDC,HADHB,UPRT,NDUFB9,SLC26A2,OGG1,KCNAB2,PGAP2,DPM1,RRM2,PRPSAP1,STOML2,ABHD5,AGPAT2,PRDX5,MLYCD,DHTKD1,COX5A,UQCRH,CLN3,NUDT11,CHPT1,PFKP,COX5B,NDUFV2,PIGN,RRM1,NDUFA4,COX4I1,CYCS,NDUFS7,NDUFS4,CHKA,PDXP,NUS1,INPP5A,ATIC,MSH2,PIGG,ATP6V0A2,PCYT2,CYC1,PIKFYVE,LPCAT1,FDFT1,PIGT,NUDT4,PGS1,PIP4K2C,DCTD,MPG,PI4K2A,ADSS,CAT,DCK,PRPS2,COX7A2L,LPCAT4,TBPL1,MDH1,SAMD8,SMPD4,GPI,PTDSS1,NUDT3,NDUFA5,KARS,SUCLG1,UGP2,MDH2,OLA1,UCK2,UCK1,CHKB,ADPGK,SLC35B2,ATP6V1B2,LCLAT1,GGPS1,CPNE3,VAV1,FLAD1,MTMR4,DUT,ADCY9,LPIN2,MINPP1,TALDO1,GPD1L,ADCY7,GPX4,CPNE1,ATP6V0A1,MTMR6,PFKFB3,NDUFA7,OGDH,NDUFB1,TAZ,PDHX,HINT1,NDUFA11,MBOAT1,PDXK,GALK1,NADSYN1,NDUFS1,CDS2,MECP2,TKT,AGPAT3,ABHD14B,ARF1,IP6K2,PMVK,PIP4K2A,NEIL2,PIP5K1C,ERH,FGFR3,NDUFV1,GART,NDUFA2,PTEN,NDUFB4,PTPN11,NDUFS8,NDUFA3,IMPA2,LDHB,AMPD2,TGFB1,TK1,GUK1,LDHA,ADSL,PNPLA8,PDE3B,HSPA1B,MTMR3,PLAA,DBI,COX8A,IMPDH1,FAM126A,NDUFS5,IDH3B,PGAM1 |
| 1.239e-04 | -9.00 | REACTOME_SIGNALING_BY_INSULIN_RECEPTOR | MSigDB lists | REACTOME_SIGNALING_BY_INSULIN_RECEPTOR | 105 | 31 | 17377 | 2626 |
PDPK1,PRKAB1,NRAS,TSC2,AKT2,RAF1,PRKAA1,KRAS,ATP6V1B2,PDE3B,MAP2K2,RHEB,MAPK3,EEF2K,FGFR3,ATP6V0B,TSC1,ATP6V1D,SHC1,PIK3R2,CAB39,ATP6V0A2,ATP6V0C,STK11,ATP6V1C1,MAPK1,ATP6V0D1,HRAS,ATP6V0E1,MLST8,ATP6V1G1 |
| 1.243e-04 | -8.99 | DUSP19 (dual specificity phosphatase 19) | protein interactions | 142679 | 73 | 25 | 17029 | 2761 |
SRM,EIF5A,TIMMDC1,DHPS,DCTN2,COX4I1,ATP5MF,HDGFL2,AP3S1,PARK7,RHEB,HDDC2,CAPN2,PPP2CA,RAP1A,PFDN4,ARF5,PRDX5,COX5A,ACTB,DHFR2,TCEA1,MAP3K5,MAPK1,NAA35 |
| 1.243e-04 | -8.99 | TAF10 (TATA-box binding protein associated factor 10) | protein interactions | 6881 | 73 | 25 | 17029 | 2761 |
FTL,ERCC1,KAT2A,SMARCA4,SUPT20H,TAF6L,USP22,ANLN,SUPT7L,UBE2I,PCBP1,SNAPC4,DHX15,POLR2A,TAF2,SAP130,RPS27A,ARHGEF1,ARHGEF2,KPNA2,TAF5L,TAF12,TAF6,SGF29,SPTAN1 |
| 1.245e-04 | -8.99 | RNA-dependent ATPase activity | molecular function | GO:0008186 | 68 | 23 | 17224 | 2647 |
DDX28,DDX47,SNRNP200,DDX24,DHX29,HELB,YTHDC2,DHX9,DHX8,DDX20,DDX39A,DHX15,DHX57,DDX23,DDX17,DDX56,UPF1,EIF4A3,DHX16,DDX31,DDX5,DDX42,DDX52 |
| 1.245e-04 | -8.99 | MYBBP1A (MYB binding protein 1a) | protein interactions | 10514 | 125 | 37 | 17029 | 2761 |
NIFK,RPS2,NOP2,MECP2,CUL1,SND1,WDR5,UBE2I,APP,LMNA,RPL23A,LYAR,DDX56,PCNA,MCM5,RBM34,ZNF746,TARDBP,FTSJ3,CDC5L,STAU1,VHL,RIOX2,RNPS1,CUL3,RPL6,RPS24,BRCA1,CAND1,UBTF,C1orf131,HNRNPR,RPS14,BAZ1B,RRS1,CCDC59,GPATCH4 |
| 1.248e-04 | -8.99 | neutrophil activation involved in immune response | biological process | GO:0002283 | 485 | 104 | 17256 | 2622 |
RHOG,ADA2,RAB14,ADAM10,DYNLL1,RAC1,HEXB,NIT2,NHLRC3,GYG1,MAPK14,KCMF1,CMTM6,CPNE3,PA2G4,RAP1A,PSMD1,AP1M1,BRI3,TMBIM1,GM2A,KCNAB2,ENPP4,CPNE1,CCT2,TIMP2,NRAS,RAB7A,ARHGAP45,PPIE,CYSTM1,PSMB7,ATP6V0A1,RAB5B,TOLLIP,ALDH3B1,DSN1,AGPAT2,DDOST,SURF4,RAB24,PSMD3,CAB39,CANT1,ATP6V0C,ROCK1,PDXK,LTA4H,MAPK1,CAPN1,TUBB,SVIP,MIF,DNAJC5,GMFG,MANBA,PDAP1,LAMTOR3,B4GALT1,ASAH1,CDK13,MAN2B1,RAB6A,PSEN1,TMEM179B,GNS,CD59,PSMD2,CTSS,ARPC5,HUWE1,OSTF1,CNN2,MVP,LPCAT1,SPTAN1,CYFIP1,FTL,MLEC,RHOA,CREG1,C1orf35,HEBP2,PKM,ARMC8,CCT8,NEU1,HSPA1B,CAND1,XRCC5,CAT,RAB18,ATP6V1D,MAGT1,GOLGA7,SNAP29,SNAP23,ACLY,PGRMC1,IMPDH1,CTSA,PSAP,GPI,PGAM1 |
| 1.250e-04 | -8.99 | regulation of protein dephosphorylation | biological process | GO:0035304 | 128 | 36 | 17256 | 2622 |
PPP1R37,PPP1R2,PPP1R12A,PPP1R15B,ENSA,PPP1R16B,CALM2,PPP1R3B,FKBP1A,UBXN2A,PIN1,PPP1R8,PPME1,PPP4R1,NSFL1C,CRY2,GNAI2,PPP6R1,TGFB1,ANKLE2,SHOC2,PPP1R9B,GBA,CDCA2,SYMPK,MASTL,TSC1,PPP2R5A,NSMF,UBXN2B,PPP1R11,CABIN1,ROCK1,PPP6R3,IGBP1,PPP2R2D |
| 1.252e-04 | -8.99 | HELLER_HDAC_TARGETS_SILENCED_BY_METHYLATION_DN | MSigDB lists | HELLER_HDAC_TARGETS_SILENCED_BY_METHYLATION_DN | 265 | 63 | 17377 | 2626 |
SRM,CYTIP,HSPH1,MAGEH1,MRPS15,KLHL21,FAM129A,ANK3,UCK2,BCL2L1,DNAJB1,PMF1,IL21R,ITGB5,PPP1R16B,DNAJB9,CFLAR,ZNF804A,DST,CDKN2C,CAPN2,IRF4,FGFR3,TNS3,NUP210,SLC1A4,GSDMB,CDKN1B,SUCLG2,BCL2,RBM3,CYC1,PLCL2,EIF5,PDIA6,NOL12,POU2AF1,IFRD1,SELPLG,TLK1,MFNG,MYBL2,ILF3,WIPF1,CADM1,PDE3B,HSPA1B,FAS,ALDH3B1,STAT6,WNT5B,PITX1,CEBPG,OGT,CCDC69,GAS2,ZMIZ1,USF2,E2F2,LRP8,EYA2,CDKN2A,IFI16 |
| 1.257e-04 | -8.98 | KOYAMA_SEMA3B_TARGETS_DN | MSigDB lists | KOYAMA_SEMA3B_TARGETS_DN | 372 | 83 | 17377 | 2626 |
NDUFA5,ASH1L,CORO7,NQO1,IVNS1ABP,TAP1,CUL1,LACTB2,SDHA,DECR1,NOL11,SYNM,TBC1D22A,XRCC2,RAB4A,AKR1B1,CABLES2,SENP1,SRPK2,PLK1,NRAS,KLF10,BIRC3,PSMA8,ANKRD33B,DRAP1,SHCBP1,CBFB,PSMB9,PLEKHF2,CXXC4,RPL37,DAP3,ACYP1,STAT6,LUC7L3,FKBP5,SNRPG,TRAF5,SLC12A7,TMUB1,GOLPH3L,KRBA1,SCAMP3,TRIP12,PRKAA1,NKD2,RGS2,ETS1,CDC73,XPR1,FASTKD3,FKBP1A,DTL,TNS3,KLHL5,KLHL20,PTPN11,ABCD1,FBXL7,TAGLN2,PTGES3,MAP3K14,IMPA2,PGS1,SSR2,C1orf35,CAPZA2,PNPLA8,ZP3,ARPC1A,KLF6,HSPA1B,XRCC5,HMGN2,ZNF862,SLCO4A1,PDCD6,TTC13,TYW5,EXOC4,GPATCH4,ALS2 |
| 1.261e-04 | -8.98 | nuclear DNA replication | biological process | GO:0033260 | 40 | 16 | 17256 | 2622 |
GINS1,POLA2,RFC3,PRIM2,CDT1,WDR18,SLBP,RFC2,PRIM1,RPA1,RPA2,UPF1,PCNA,POLE,ZNF830,ORC3 |
| 1.262e-04 | -8.98 | human chr19p13.3 | chromosome location | human chr19p13.3 | 232 | 44 | 26185 | 2809 |
RPS15,SH2D3A,TRIP10,MUM1,TCF3,C19orf25,HDGFL2,SAFB2,NDUFS7,GTF2F1,PIP5K1C,VAV1,KLF16,MRPL54,SCAMP4,CNN2,MYDGF,MFSD12,GPX4,CSNK1G2,ARHGAP45,GNG7,WDR18,CIRBP,MIER2,MBD3,MAP2K2,SF3A2,SPPL2B,DAPK3,RPL36,DOT1L,CHAF1A,TIMM13,DUS3L,SAFB,NDUFA11,GADD45B,YJU2,KHSRP,TICAM1,NCLN,STK11,OAZ1 |
| 1.262e-04 | -8.98 | EBNA-1 (nuclear antigen EBNA-1;) | protein interactions | 3783709 | 12 | 8 | 17029 | 2761 |
USP7,KPNA1,PML,CSNK2A1,EBNA1BP2,HMGB2,NAP1L4,RPA1 |
| 1.262e-04 | -8.98 | RNU1-1 (RNA, U1 small nuclear 1) | protein interactions | 26871 | 12 | 8 | 17029 | 2761 |
GEMIN5,DDX20,GEMIN6,GEMIN4,SND1,STRAP,CDC5L,GEMIN7 |
| 1.263e-04 | -8.98 | CHEN_HOXA5_TARGETS_9HR_UP | MSigDB lists | CHEN_HOXA5_TARGETS_9HR_UP | 203 | 51 | 17377 | 2626 |
IER2,DNAJC2,PRPF38B,PPP1R12A,ZCCHC8,FAM53C,ZNF107,ZNF267,IP6K2,RLF,FOXO3,BIRC2,YY1AP1,CREM,PTPN2,PPIG,TANK,EIF5,RBM15,TIPARP,SCYL3,MORC3,RYBP,SRSF10,CDKN2AIP,IFRD1,TNFAIP3,BIRC3,KLF10,PSPC1,PGS1,SREK1,MCL1,PPWD1,PRPF3,DCLRE1C,KDM3A,KLF6,SLTM,TAF2,ZNF180,KIF18A,NEK1,ETS2,GADD45B,NFIL3,ARNTL,CEBPG,CAB39,ZNF45,IFI16 |
| 1.269e-04 | -8.97 | STAT1 (signal transducer and activator of transcription 1) | protein interactions | 6772 | 190 | 51 | 17029 | 2761 |
MBD1,KARS,LZTR1,GSPT2,RAC1,SMARCA4,JMJD6,PAWR,UBE2I,MAPK14,GNB2,PTPN2,FGFR3,CTNNBL1,HUWE1,MCM5,AHSA1,PTPN11,MAVS,STAT3,CAMK2G,DCTN1,MLST8,SPTAN1,SNX2,RTF1,BRCA1,FANCE,TRIM28,FADD,ISG15,DOT1L,CAND1,HLA-B,IDE,KPNA1,JAK1,NSF,DUSP3,STAT1,PML,E2F1,KPNA2,ATP6V1C1,ARRB2,IGBP1,SMURF1,NMD3,DDB1,VPS29,USP13 |
| 1.269e-04 | -8.97 | - | gene3d domains | 3.10.110.10 | 54 | 20 | 8148 | 1295 |
UBE2D3,UBE2E2,RWDD1,RNF25,UFC1,UBE2Q1,UBE2Z,UBE2V1,KRAS,EIF2AK4,UBE2I,FANCL,UBE2Q2,UEVLD,WDR59,RWDD4,RNF14,UBE2C,UBE2M,UBE2QL1 |
| 1.275e-04 | -8.97 | LDHC (lactate dehydrogenase C) | protein interactions | 3948 | 24 | 12 | 17029 | 2761 |
BRD4,WDR1,ARF5,LDHA,MDH1,BRCA1,ARF1,TALDO1,RAB1A,ARF4,SRPK2,LDHB |
| 1.275e-04 | -8.97 | CCDC102A (coiled-coil domain containing 102A) | protein interactions | 92922 | 24 | 12 | 17029 | 2761 |
DSN1,BIRC5,CCDC6,VPS26B,GOPC,ODF2,LACTB,MYH9,PDIA6,PIP4K2A,RAB3IL1,PTPRK |
| 1.275e-04 | -8.97 | TRNT1 (tRNA nucleotidyl transferase 1) | protein interactions | 51095 | 24 | 12 | 17029 | 2761 |
H2AFZ,SH3BP1,GNPDA1,ATIC,CPOX,UBXN1,EZR,CTSA,H2AFV,CLNS1A,USP5,RAD23A |
| 1.275e-04 | -8.97 | ADARB1 (adenosine deaminase, RNA specific B1) | protein interactions | 104 | 24 | 12 | 17029 | 2761 |
NIFK,STRBP,PIN1,LRPPRC,USP39,C1orf35,EBNA1BP2,RRS1,BRIX1,APP,ZFR,WWP2 |
| 1.276e-04 | -8.97 | UBE2D1 (ubiquitin conjugating enzyme E2 D1) | protein interactions | 7321 | 248 | 63 | 17029 | 2761 |
DDX58,UNK,TRIP12,TRAF7,NQO1,TRIM11,XIAP,TKT,KCTD17,UBE4A,BIRC2,RNF103,WWP2,DTL,RFWD3,HERC3,MDM2,BABAM2,PTEN,SIAH1,ZNRF2,HUWE1,SIVA1,MARCH2,UBE3C,AHCYL1,RNF26,TTLL12,LRSAM1,RNF5,RLIM,USP34,CDC5L,TRIM8,TNFAIP3,BIRC3,RBX1,VHL,WDR1,RNF25,CUL3,PSMB7,RFFL,KRAS,TOPORS,UBE4B,BRCA1,MCM2,TRIM28,CAND1,BRMS1,MKNK1,TRIM26,WDR4,SIAH2,RNF38,UHRF2,TRIM32,RNF14,IGBP1,SMURF1,SSSCA1,RNF114 |
| 1.277e-04 | -8.97 | LEE_RECENT_THYMIC_EMIGRANT | MSigDB lists | LEE_RECENT_THYMIC_EMIGRANT | 198 | 50 | 17377 | 2626 |
MIF,ZCCHC9,ABCC10,TRIO,XIAP,TKT,SIKE1,THRAP3,PM20D2,QSOX2,RGS1,SLC25A37,ARL6IP6,PAPOLA,FUT8,DAPK1,TRA2B,FNIP2,TAGLN2,N4BP2,ARL5A,SMC4,PRPF19,TIMM8B,TIMP2,RHOBTB3,TNFAIP3,ANKRD37,OXR1,ITM2A,NFATC2IP,NDUFA7,SOX4,STK17B,ISG15,ANKRD10,RAB18,SERF2,PDLIM1,CDCA7L,FAM3C,LRPPRC,USP32,FAM126A,RPS26,TOB1,IFI16,HDAC2,PDCD4,ZNF720 |
| 1.280e-04 | -8.96 | RPS27L (ribosomal protein S27 like) | protein interactions | 51065 | 69 | 24 | 17029 | 2761 |
UNK,RPS2,RPLP2,VHL,RPL6,ILF3,RPL15,RPS24,SNRPD3,MCM2,RPL27A,RPSA,RPL11,RPL23A,PA2G4,MDM2,SYNCRIP,IARS,RPL17,ZNF746,RPL19,FAU,CTDSP2,CDC37 |
| 1.280e-04 | -8.96 | SSR1 (signal sequence receptor subunit 1) | protein interactions | 6745 | 69 | 24 | 17029 | 2761 |
CCT2,SEC61B,PHB2,ILF3,CUL3,NUP54,TMEM216,ODC1,SRSF1,CAND1,RPN1,DDOST,MAGT1,HUWE1,ERGIC3,LTN1,CYC1,PSAP,TECR,ATP6V1C1,LMAN1,ATP6V0D1,HNRNPM,TMX1 |
| 1.280e-04 | -8.96 | NUF2 (NUF2, NDC80 kinetochore complex component) | protein interactions | 83540 | 69 | 24 | 17029 | 2761 |
CCDC93,CTDP1,MAX,RPRD1A,WDYHV1,MYBL2,RCOR1,AURKB,PMF1,PSMD9,GIT2,HMG20A,MIS12,ATG4A,OIP5,PCM1,SP100,DSN1,GRIPAP1,RABGAP1L,PPIG,ARNTL,NSFL1C,CDC5L |
| 1.280e-04 | -8.96 | PAK5 (p21 (RAC1) activated kinase 5) | protein interactions | 57144 | 69 | 24 | 17029 | 2761 |
PLK1,USP7,CCDC138,MRPL39,UBR2,RAC1,CHCHD2,XPNPEP3,COA7,AMZ2,NDUFV1,IDE,CDC42,EXOSC1,ARHGEF2,YWHAZ,ARRB2,PITRM1,ZNF598,AP2S1,CARMIL1,GCC1,CCDC59,HTRA2 |
| 1.280e-04 | -8.96 | MRPL40 (mitochondrial ribosomal protein L40) | protein interactions | 64976 | 69 | 24 | 17029 | 2761 |
MRPL9,MRPL42,PHB2,MRPL39,TAP1,MRPL12,MRPL43,ILF3,MRPL16,MRPL19,STOML2,SDHB,MRPL50,MRPL2,ATP6V1D,ATP1A1,MRPL55,HNRNPR,MPV17,UPF2,MRPL11,MRPL21,MRPL32,CDC5L |
| 1.280e-04 | -8.96 | G3BP2 (G3BP stress granule assembly factor 2) | protein interactions | 9908 | 69 | 24 | 17029 | 2761 |
CYLD,DDX24,IVNS1ABP,SUZ12,CUL3,CUL1,USP10,ADSL,PABPC4,CAND1,WWP2,MDM2,PTEN,PIN1,ATXN2L,RPF2,NUP62,NUP153,TARDBP,CDK2,ARRB2,RPL22L1,PABPC1,TERF2 |
| 1.282e-04 | -8.96 | SCIAN_CELL_CYCLE_TARGETS_OF_TP53_AND_TP73_DN | MSigDB lists | SCIAN_CELL_CYCLE_TARGETS_OF_TP53_AND_TP73_DN | 22 | 11 | 17377 | 2626 |
MAPRE2,CCNA2,TPX2,KIF23,GTSE1,KIF22,CDC25B,CCNB1,CCNF,CDK2,UBE2C |
| 1.282e-04 | -8.96 | GALLUZZI_PREVENT_MITOCHONDIAL_PERMEABILIZATION | MSigDB lists | GALLUZZI_PREVENT_MITOCHONDIAL_PERMEABILIZATION | 22 | 11 | 17377 | 2626 |
BAK1,TXN,WDTC1,VDAC2,MCL1,BCL2,BCL2L1,VDAC1,PRKACA,MAPK14,GPX4 |
| 1.284e-04 | -8.96 | leukocyte degranulation | biological process | GO:0043299 | 502 | 107 | 17256 | 2622 |
RHOG,ADA2,RAB14,ADAM10,DYNLL1,RAC1,HEXB,NIT2,NHLRC3,GYG1,MAPK14,LYN,KCMF1,CMTM6,CPNE3,PA2G4,RAP1A,PSMD1,AP1M1,BRI3,CORO1A,TMBIM1,GM2A,KCNAB2,ENPP4,CPNE1,CCT2,TIMP2,NRAS,RAB7A,ARHGAP45,PPIE,CYSTM1,PSMB7,ATP6V0A1,RAB5B,TOLLIP,ALDH3B1,DSN1,AGPAT2,DDOST,SURF4,RAB24,PSMD3,CAB39,CANT1,ATP6V0C,ROCK1,PDXK,LTA4H,MAPK1,CAPN1,TUBB,SVIP,MIF,DNAJC5,GMFG,MANBA,PDAP1,LAMTOR3,B4GALT1,ASAH1,CDK13,MAN2B1,RAB6A,PSEN1,TMEM179B,GNS,CD59,PSMD2,CTSS,ARPC5,HUWE1,OSTF1,CNN2,MVP,LPCAT1,SPTAN1,CYFIP1,FTL,MLEC,RHOA,CREG1,C1orf35,HEBP2,PKM,ARMC8,CCT8,NEU1,HSPA1B,PI4K2A,CAND1,XRCC5,CAT,RAB18,ATP6V1D,MAGT1,GOLGA7,SNAP29,SNAP23,ACLY,PGRMC1,IMPDH1,CTSA,PSAP,GPI,PGAM1 |
| 1.284e-04 | -8.96 | HK1 (hexokinase 1) | protein interactions | 3098 | 53 | 20 | 17029 | 2761 |
STAU1,UBXN1,HEXB,VDAC2,TUFM,VDAC1,TWF2,CDC73,APP,CAPN2,PCNA,PDCD10,PLAA,UBA5,NSFL1C,AHCY,CDK2,NIPSNAP2,HEXA,ATF2 |
| 1.285e-04 | -8.96 | protein serine/threonine phosphatase complex | cellular component | GO:0008287 | 49 | 18 | 18223 | 2701 |
PPP1R9B,SHOC2,PPP3CA,PPP1R2,PPP1R12A,NCK1,PPP1R15B,STRN4,WDR82,CYCS,PPP3CB,PPP1R3B,PPP2CA,PPP2R5A,PPP4R1,PPP3R1,PPP1R11,PPP2R2D |
| 1.285e-04 | -8.96 | phosphatase complex | cellular component | GO:1903293 | 49 | 18 | 18223 | 2701 |
PPP1R9B,SHOC2,PPP3CA,PPP1R2,PPP1R12A,NCK1,PPP1R15B,STRN4,WDR82,CYCS,PPP3CB,PPP1R3B,PPP2CA,PPP2R5A,PPP4R1,PPP3R1,PPP1R11,PPP2R2D |
| 1.286e-04 | -8.96 | cytoskeleton | cellular component | GO:0005856 | 2120 | 372 | 18223 | 2701 |
FGFR1OP,PDCD6IP,ADD1,TAP1,CNTROB,CCNB1,ANKRD23,KIFC1,CDK5,CALM2,ANKRD26,NEK6,DNM2,MAST2,CDC25B,SPATC1L,KCNAB2,PLK3,SGCE,RHOBTB3,NSUN2,KIF15,DDX20,TOPORS,AURKB,DIDO1,CCNF,MCM2,SLC25A5,RAB22A,CLNS1A,EIF3A,KRIT1,STOML2,AHNAK,WAS,MID1IP1,RAD18,KIF18B,WDR11,MAP4,MYO18A,PTPN7,KLHL42,SLF1,TRAF5,AAAS,ANXA11,DDX58,HSPH1,MAPRE1,DHX9,RAB23,KIF23,HAUS4,PSEN1,HAUS2,MYL6B,LMNA,SPAG5,JMY,RTKN,TMEM250,CEP104,PDXP,SMC3,KLHL5,ARPC5,RIMS3,DAPK1,FBXL7,MVP,GNAI2,NUP85,WDR1,SEPT8,MAP7D1,PLEC,CAPZA2,MAP2K2,CCT8,FNTA,PDLIM1,GOLGA2,FAM83D,SLAIN1,NDE1,CFAP20,PDLIM5,CDK2,ALS2,ZNF207,RHOG,NDC1,IVNS1ABP,TRIP10,POC1A,ANK3,ACTR3,RAC1,OLA1,TPX2,MYH9,NIT2,BCL2L1,PRKACA,STMN1,APP,CLUAP1,MTA1,NSFL1C,SEPT11,RNF19A,CEP63,RPRD1B,CFL1,DCTN1,CCT2,PSRC1,MAPRE2,NARF,CUL3,NUSAP1,DNAJA1,SHCBP1,SERP1,EML4,CENPU,PPP2CA,KIF2A,CDC16,DSN1,JAK1,HINT1,PPP2R5A,CCDC14,FAAP100,CORO1C,H2AFX,TRIM32,GEN1,LRP8,CSNK1D,TUBB,DYNC1LI2,MZT1,PKP4,SESTD1,MECP2,FLOT1,WDR5,SPDL1,IFT27,RAB11A,MAD2L2,NEIL2,JAKMIP1,CAPN2,ADD3,CLIC4,CENPJ,PRC1,AXIN2,GTSE1,KANSL2,CNN2,SGCB,IFT46,SPTAN1,NUDC,PDLIM2,STAU1,KAT2A,TCTEX1D2,TACC1,NEK7,JTB,PARP4,RAB3IP,MACF1,KIF11,MARK2,SPPL2B,MYO1F,CBX3,KIF18A,KEAP1,CCDC6,TTLL4,MAPK6,LRPPRC,CCDC69,SSNA1,WDR62,ESPL1,DEF6,NPHP4,SKA3,KMT2E,WDR13,DNAJC24,KIF2C,CDC42SE2,SIRT2,MAPK14,MAP1LC3B,DST,DLG5,ZNF804A,ABL2,RAB8A,PCNA,SYNM,CDC42,DPYSL2,RCSD1,XRCC2,KIF22,RP2,MTPN,CARMIL1,TACC3,PLK1,RPP25,SEPT9,PBXIP1,FOPNL,TMEM216,CKAP2L,EZR,CDC6,ARHGDIB,BRCA1,ANLN,STK17B,DPYSL3,EPB41,SEPT1,HSPB11,CHD3,ACTB,ZNF268,VPS4A,ROCK1,DVL1,CLU,SASS6,C2CD5,MYL12B,CEP170B,TMUB1,PPP1R12A,CENPF,CIB1,KLC1,RACGAP1,NCKAP1,RAPGEF6,DTL,RB1,VASP,CCP110,RINL,KIF13B,CAPZA1,KIFAP3,KNTC1,MCPH1,ATP6V0D1,CAMSAP1,PSMA1,SEPT7,ARPC1A,DAPK3,ZNF174,EVC2,MASTL,HAUS8,TSC1,PCM1,CDC27,NSMF,ODF2,NLRC5,SLC16A1,NUP62,RUVBL2,MYO9A,ECPAS,CCNB2,MZT2B,BCCIP,WASF2,CYLD,FAM92A,DYNLL1,SLC2A1,PMS2,TWF2,RAD23A,ABRACL,STRBP,ABRAXAS2,KIF14,CORO1A,ABI1,HTRA2,POC5,DNAL4,CHP1,PRPF19,PPP1R18,TUBGCP5,WIPF1,BICD2,TMEM201,CLK3,TULP3,CEP55,GAS2,AKNA,REEP4,MAPK1,SMAD4,PARD3,RAD51D,SLC30A9,CTDP1,KIF3B,KLHL21,RAE1,DCTN2,CDK2AP2,SCYL1,CDCA8,PAWR,MYO9B,CSNK1A1,TUBGCP2,SAC3D1,FBXO5,FERMT3,KIF5B,STARD9,MZT2A,KLHL20,SLC1A4,ARHGEF2,TTC17,FRMD8,MYO5A,MICAL3,PPP1R9B,ADAM17,RHOA,ASPM,RANGAP1,SYMPK,TARS,MAPK3,HSPA1B,MFN2,NEK1,ATP6V1D,BIRC5,FAM110A,SNAP29,E2F1,USP20,PKD2,PREPL,TERF1 |
| 1.289e-04 | -8.96 | RPS6KA1 (ribosomal protein S6 kinase A1) | protein interactions | 6195 | 90 | 29 | 17029 | 2761 |
PDPK1,METTL1,ATXN3,TSC2,RPS6KA1,GMFB,LDHA,SRSF5,FAM136A,EIF4H,MXD1,MAPK3,EEF2K,MASTL,GNS,TSC1,PPM1G,CDKN1B,YBX1,CREB1,MAPK1,TOB1,ILKAP,CAPN1,CFL1,EEF1D,PDCD4,LDHB,CDC37 |
| 1.289e-04 | -8.96 | ATXN3 (ataxin 3) | protein interactions | 4287 | 90 | 29 | 17029 | 2761 |
TK1,PSRC1,ATXN3,EWSR1,NDUFAF2,DNAJB2,RPS6KA1,SDC2,RFFL,UBE4B,BCL2L1,SYVN1,APP,USP21,HLA-A,RAD23A,CAPN2,MKNK1,TIMM23,RAD23B,PML,DNM2,BCL7C,SRI,CNOT6,CREB1,SMURF1,TUBB,USP13 |
| 1.289e-04 | -8.96 | GSE17721_CTRL_VS_PAM3CSK4_0.5H_BMDC_UP | MSigDB lists | GSE17721_CTRL_VS_PAM3CSK4_0.5H_BMDC_UP | 193 | 49 | 17377 | 2626 |
TMED7,PRPF38B,KARS,RPS2,ADD1,HJURP,KIAA0100,SEC61G,ANKH,TIA1,SNRPD3,CHD1,CMTM6,TMEM179B,ANKRD28,AHCTF1,SHC1,DAD1,RP2,CNOT6L,HNRNPM,CGGBP1,RNF5,SOCS5,TRIM8,RPRD1A,TK1,ERLIN1,NSUN2,PSMB7,TMEM216,SEPT8,NDUFA7,SRSF1,EIF3K,PLAA,JAK1,CCDC6,SNAP23,PIAS2,TBPL1,LY75,MDH1,KLHDC4,CDK2,CHMP7,GCSH,STARD3NL,CCDC137 |
| 1.289e-04 | -8.96 | GSE13484_3H_UNSTIM_VS_YF17D_VACCINE_STIM_PBMC_UP | MSigDB lists | GSE13484_3H_UNSTIM_VS_YF17D_VACCINE_STIM_PBMC_UP | 193 | 49 | 17377 | 2626 |
RMND5A,ZCCHC8,DYNLL1,TSC22D3,MCCC1,RAB6A,GGA2,MEAF6,BCAT2,PAPOLA,ATP6V0B,ATIC,DNAAF2,MAVS,CYC1,PIK3IP1,HTRA2,IMPA2,FDFT1,FTL,TRIM8,MIOS,ABCF2,PIP4K2C,FRAT2,FBXO9,BICD2,ESYT1,PTTG1IP,RDH11,AKAP1,AMZ2,MKNK1,OSBPL11,PRDX3,PFDN4,NSF,LUC7L3,FASTK,TFDP1,APPL2,ACBD4,UQCRH,MRFAP1L1,ZNF268,ATP6V1C1,MAPK1,COIL,RNF114 |
| 1.289e-04 | -8.96 | GSE28237_FOLLICULAR_VS_EARLY_GC_BCELL_DN | MSigDB lists | GSE28237_FOLLICULAR_VS_EARLY_GC_BCELL_DN | 193 | 49 | 17377 | 2626 |
CORO7,CCM2,CUL1,RRAGC,TOP2B,AP3S1,WRB,NUP205,ATP2A2,ARPC5,KIF14,PRDM4,NUP107,PTPN11,SUCLG2,SS18L1,RNF19A,LRRC59,PABPC1,NUDC,CDC5L,EIF5A,VOPP1,SRSF11,CDC123,ASPM,NSDHL,PBK,SMU1,CDC6,MRPL16,SEPT7,FXR1,CCNF,ZFAND5,PDE3B,API5,GLOD4,ADSS,NSA2,CDC16,GALNT2,CDCA7L,CEP55,CDCA5,HMGB2,ANP32E,KPNA2,NGLY1 |
| 1.291e-04 | -8.96 | proteasome complex | cellular component | GO:0000502 | 66 | 22 | 18223 | 2701 |
TXNL1,UBQLN4,PSMA8,UBXN1,PSMB7,PSMA1,PSMD9,PSMB9,PSMB3,PSMC4,RAD23A,PSMD2,PSMA6,PSMD1,IDE,PSMD8,UCHL5,PSMD3,RAD23B,UBE3C,ECPAS,PSMC1 |
| 1.296e-04 | -8.95 | stomach-carcinoma-undifferentiated_adenocarcinoma | COSMIC cancer mutations | stomach-carcinoma-undifferentiated_adenocarcinoma | 53 | 19 | 17385 | 2587 |
NRAS,NF1,VHL,KRAS,BRCA1,ARID1A,KMT2C,GNAS,RB1,FGFR3,PTEN,MSH2,PTPN11,STK11,H3F3A,SMAD4,HRAS,MSH6,CDKN2A |
| 1.296e-04 | -8.95 | undifferentiated_adenocarcinoma | COSMIC cancer mutations | undifferentiated_adenocarcinoma | 53 | 19 | 17385 | 2587 |
NRAS,NF1,VHL,KRAS,ARID1A,BRCA1,KMT2C,GNAS,RB1,FGFR3,PTEN,PTPN11,MSH2,STK11,H3F3A,SMAD4,HRAS,CDKN2A,MSH6 |
| 1.297e-04 | -8.95 | GSE21927_SPLENIC_C26GM_TUMOROUS_VS_BONE_MARROW_MONOCYTES_DN | MSigDB lists | GSE21927_SPLENIC_C26GM_TUMOROUS_VS_BONE_MARROW_MONOCYTES_DN | 163 | 43 | 17377 | 2626 |
FEZ2,NOP2,KLHL21,AP3M2,NENF,BCL2L1,SUPT7L,STMN1,SNRNP25,UTP18,RIMS3,SLC35B4,EI24,DDX31,ALDH18A1,PDIA6,SLC12A2,NDUFA3,ABI1,PDLIM2,FYTTD1,PPIF,SEC61B,CSRP1,CREG1,NFATC2IP,ISG15,ANKRD46,EPRS,FNTA,TIMM13,HINT1,UAP1,DUSP3,CCDC6,NDUFA11,NFIL3,LRPPRC,COX5A,RBPJ,ZNF830,ANAPC4,USP13 |
| 1.297e-04 | -8.95 | GSE9509_10MIN_VS_30MIN_LPS_AND_IL10_STIM_IL10_KO_MACROPHAGE_UP | MSigDB lists | GSE9509_10MIN_VS_30MIN_LPS_AND_IL10_STIM_IL10_KO_MACROPHAGE_UP | 163 | 43 | 17377 | 2626 |
CASP6,KLHL21,PDAP1,CDT1,SNX15,PMS2,TKT,DHX9,CDCA3,DNAJC24,KIF23,HAUS4,ABHD14B,ADPGK,LANCL1,ZBTB45,CLUAP1,NOL11,ARHGEF1,ZDHHC13,MRPS27,PRC1,GPATCH1,TTC3,METTL1,NUDT8,GUK1,TYW1,CLNS1A,PRIM1,CHCHD3,CDKN2AIPNL,ACYP1,CCDC14,COX8A,NDE1,PPP5C,SNRNP70,PITRM1,TOB1,MYL12B,DDB1,RAD51D |
| 1.298e-04 | -8.95 | GO_U2_TYPE_SPLICEOSOMAL_COMPLEX | MSigDB lists | GO_U2_TYPE_SPLICEOSOMAL_COMPLEX | 29 | 13 | 17377 | 2626 |
LUC7L3,SF3B1,SNRPB,SNRPG,SNRPD3,SNRNP70,PRPF39,LUC7L,SF3A2,DHX15,PRPF18,LUC7L2,SF3B2 |
| 1.298e-04 | -8.95 | CHOW_RASSF1_TARGETS_DN | MSigDB lists | CHOW_RASSF1_TARGETS_DN | 29 | 13 | 17377 | 2626 |
PPIB,CELSR2,CREG1,POLR2K,PRKCSH,KLHL21,PSMG1,NDUFS8,LY6E,EEF1D,RNF114,EBAG9,OPTN |
| 1.298e-04 | -8.95 | GO_REPLISOME | MSigDB lists | GO_REPLISOME | 29 | 13 | 17377 | 2626 |
POLA2,RPA2,PCNA,POLE,PRIM2,TONSL,HELB,XPA,PURA,RPA1,PRPF19,CDC5L,PRIM1 |
| 1.298e-04 | -8.95 | CAFFAREL_RESPONSE_TO_THC_24HR_5_UP | MSigDB lists | CAFFAREL_RESPONSE_TO_THC_24HR_5_UP | 29 | 13 | 17377 | 2626 |
PCNA,RPS2,FNTA,CCNA2,IARS,RBX1,KHSRP,SLC29A1,EIF2A,MYL6B,TFRC,TUBB,DDB1 |
| 1.298e-04 | -8.95 | GSE3982_DC_VS_NEUTROPHIL_UP | MSigDB lists | GSE3982_DC_VS_NEUTROPHIL_UP | 188 | 48 | 17377 | 2626 |
ST13,CHD1L,LAGE3,RRM1,GLUD1,PXMP2,GTF3A,ORC1,IL21R,TUBGCP2,DST,CCNA2,NOL11,KLHL20,INTS7,LRRC8D,DPYSL2,ATIC,KIF13B,GRSF1,BANF1,NOC2L,AKR1B1,AP2B1,BCL2,TTC4,MRPL40,FBL,LMAN1,ATP13A1,POLR2G,IDH3A,NUP155,SOX4,MAT2A,YIF1A,DTWD1,MAP3K4,EPRS,GNA12,HSPA4,HINT1,PTER,WDR7,FTSJ1,H2AFX,PURA,ACSF2 |
| 1.298e-04 | -8.95 | GSE29949_DC_BRAIN_VS_MONOCYTE_BONE_MARROW_UP | MSigDB lists | GSE29949_DC_BRAIN_VS_MONOCYTE_BONE_MARROW_UP | 188 | 48 | 17377 | 2626 |
CYLD,MUT,ADD1,TSC2,NF1,MYH9,PMF1,SLC35B1,CDIPT,UBE2I,MAPK14,REEP5,PIP4K2A,ATG4A,CAPN2,KDM2A,RALB,DPYSL2,KIF14,FUT8,FAM89B,PDS5B,ATP6V0A2,TAF5L,MAP3K14,GNAI2,SMARCE1,RYBP,ADCY7,ERCC1,LRP5,GALK2,DIDO1,ESYT1,CBFB,STK17B,MKNK1,SMAD2,AHNAK,SNAP23,MEGF9,SLC16A1,PIEZO1,RRS1,MAPK1,FAM208A,TUBB,BYSL |
| 1.298e-04 | -8.95 | GSE29164_UNTREATED_VS_CD8_TCELL_TREATED_MELANOMA_DAY3_UP | MSigDB lists | GSE29164_UNTREATED_VS_CD8_TCELL_TREATED_MELANOMA_DAY3_UP | 188 | 48 | 17377 | 2626 |
CTU2,NDUFA5,GALK1,GLT8D1,RWDD1,CKLF,C5orf30,CHIC2,NIT2,SLC4A2,ZADH2,IFT27,CHD1,RPAIN,CPNE3,TMCC3,NUDT19,SLC31A1,PRKD3,NDUFV1,ZNHIT6,DPYSL2,ADCY9,BUD31,TIMELESS,NDUFB9,RNF19A,TOP1MT,CTDSP2,CSNK1G3,METTL5,MIER1,NLN,GALNT7,VKORC1,CYB5A,DERL1,HSPA4,HSPB11,PPP2R5A,BRWD1,HINT1,NSMCE2,DBI,ARAP1,MDH1,MBOAT1,RNF139 |
| 1.298e-04 | -8.95 | GSE44649_NAIVE_VS_ACTIVATED_CD8_TCELL_MIR155_KO_DN | MSigDB lists | GSE44649_NAIVE_VS_ACTIVATED_CD8_TCELL_MIR155_KO_DN | 188 | 48 | 17377 | 2626 |
GNPNAT1,ARID2,SHPRH,YTHDC2,NKRF,CREBL2,BRIX1,MYEF2,NUP205,HEATR5B,MAN1A1,FBXO3,SLC31A1,IRF4,RAB21,C1GALT1,KLHL20,NVL,RNFT1,GRSF1,RBM34,FOXN2,INTS12,SUCLG2,RP2,MYO5A,RNLS,ADCY7,PRIM2,POLK,GABPA,DENND4C,RAD51AP1,LRBA,MTMR6,PBRM1,ICAM2,BORA,PDE3B,ASF1B,ARHGAP15,ANKRD10,TAF2,RBMX,KBTBD7,BTBD10,DDX52,SNAPIN |
| 1.298e-04 | -8.95 | GSE30962_PRIMARY_VS_SECONDARY_CHRONIC_LCMV_INF_CD8_TCELL_UP | MSigDB lists | GSE30962_PRIMARY_VS_SECONDARY_CHRONIC_LCMV_INF_CD8_TCELL_UP | 188 | 48 | 17377 | 2626 |
ABCA3,LYRM4,LUZP1,CLSPN,MRPS2,URB2,UCK2,KIF23,HMGN3,TCF19,STMN1,TUBGCP2,TFRC,PABPC4,FANCI,PCNA,COQ4,THADA,RCSD1,XRCC2,BTF3L4,NAA50,AXIN2,TIMELESS,KIF22,APOOL,IFT46,GINS1,NXT1,NOA1,RAD51AP1,EMB,PSPC1,PSMA1,PSMG1,BRCA1,SHCBP1,PLEKHF2,OPTN,PDLIM1,PML,KPNA2,FKBP5,MBOAT1,BTF3,CDK2,TSEN15,SLC25A33 |
| 1.298e-04 | -8.95 | GSE21670_STAT3_KO_VS_WT_CD4_TCELL_IL6_TREATED_UP | MSigDB lists | GSE21670_STAT3_KO_VS_WT_CD4_TCELL_IL6_TREATED_UP | 188 | 48 | 17377 | 2626 |
MANBA,TMX4,TMX3,B4GALT1,SDF2L1,ARF1,B4GALT4,DCUN1D4,AP3S1,CFLAR,PCYOX1L,RTKN,ANKRD28,CSDE1,RAB21,ZNF420,PDS5B,KIFAP3,ACAD8,MOB1A,NAGPA,FAM49B,TSPAN31,OXR1,EHMT1,KCTD20,GORASP2,GALK2,ESYT1,GOSR1,TTC33,SERP1,FKBP3,ANKRD10,DDOST,ZHX1,PTER,CAMKMT,PRDX5,SIAH2,ADAM9,ATF6,EHD4,PLOD3,LTA4H,RTN3,PFKP,SVIP |
| 1.298e-04 | -8.95 | GSE45365_HEALTHY_VS_MCMV_INFECTION_CD8A_DC_UP | MSigDB lists | GSE45365_HEALTHY_VS_MCMV_INFECTION_CD8A_DC_UP | 188 | 48 | 17377 | 2626 |
RPS6KA1,MDH2,ADO,UCK2,BTN3A1,NKRF,NIT2,TMED3,EZH1,GGA2,BLM,PRKACA,MAPK14,PCBP1,CCDC28A,NDUFS7,PCYOX1L,CALM2,TBC1D22A,ATIC,GRSF1,ANP32A,OSTF1,TTC17,HTRA2,TERF2,PGAP2,GCC2,TRAPPC9,HEMK1,TRIM8,NUP155,NDUFA7,ARID1A,MAP2K2,USP21,RPSA,HMGN2,PRIM1,KIF2A,TTC13,RPS27A,SPATA2,AXIN1,FASTK,MLYCD,ACTB,NR2F2 |
| 1.303e-04 | -8.95 | SRP-dependent cotranslational protein targeting to membrane | biological process | GO:0006614 | 91 | 28 | 17256 | 2622 |
SRP72,RPL29,RPS15,SEC61B,RPL35,RPS2,RPLP2,RPL6,RPS10,RPL38,RPL8,RPL15,RPS24,RPL27A,RPS9,RPSA,RPL23A,RPL36,RPL11,RPL37,RPL32,SEC61A1,RPL17,RPS27A,RPS14,RPLP1,RPL19,RPS26 |
| 1.303e-04 | -8.95 | Chromatin modifying enzymes | REACTOME pathways | R-HSA-3247509 | 279 | 70 | 10287 | 1696 |
ASH1L,DNMT3A,H2AFZ,KDM4A,KMT2E,ARID2,SUZ12,SMARCA4,NSD3,TAF6L,MEAF6,SAP130,KDM2A,KMT5C,BRPF3,MTA1,TAF5L,ATF2,SMARCE1,SAP30L,ARID4A,CARM1,SAP30,KDM3B,KAT7,EHMT1,RIOX2,ELP4,SUPT20H,PBRM1,USP22,KMT2C,KDM1B,H2AFV,MBD3,DOT1L,BRMS1,BRWD1,CHD3,H2AFX,OGT,ACTB,NCOA1,HDAC2,NCOR2,RPS2,JMJD6,SUPT7L,WDR5,ARID1B,SUV39H2,ELP5,KMT5A,KANSL2,NCOA2,KAT2A,MTA2,RCOR1,ARID1A,KDM3A,MBIP,GPS2,SETD3,PRMT7,KMT2B,RUVBL2,TAF12,RBBP4,SGF29,SMARCD1 |
| 1.303e-04 | -8.95 | Chromatin organization | REACTOME pathways | R-HSA-4839726 | 279 | 70 | 10287 | 1696 |
ASH1L,DNMT3A,H2AFZ,KDM4A,KMT2E,ARID2,SUZ12,SMARCA4,NSD3,TAF6L,MEAF6,SAP130,KDM2A,KMT5C,BRPF3,MTA1,TAF5L,ATF2,SMARCE1,SAP30L,ARID4A,CARM1,SAP30,KDM3B,KAT7,EHMT1,RIOX2,ELP4,SUPT20H,PBRM1,USP22,KMT2C,KDM1B,H2AFV,MBD3,DOT1L,BRMS1,BRWD1,CHD3,H2AFX,OGT,ACTB,NCOA1,HDAC2,NCOR2,RPS2,JMJD6,SUPT7L,WDR5,ARID1B,SUV39H2,ELP5,KMT5A,KANSL2,NCOA2,KAT2A,MTA2,RCOR1,ARID1A,KDM3A,MBIP,GPS2,SETD3,PRMT7,KMT2B,RUVBL2,TAF12,RBBP4,SGF29,SMARCD1 |
| 1.304e-04 | -8.94 | GSE12845_IGD_NEG_BLOOD_VS_NAIVE_TONSIL_BCELL_DN | MSigDB lists | GSE12845_IGD_NEG_BLOOD_VS_NAIVE_TONSIL_BCELL_DN | 183 | 47 | 17377 | 2626 |
CYTIP,DNMT3A,TMBIM4,B4GALT5,RPS6KA1,TMEM109,ARID5A,AGPAT3,RLF,CHKA,SNRNP25,RBM23,KDM2A,EIF4A3,ARHGEF1,XRCC2,POLR1B,KCNAB2,TGFB1,SRSF11,KLF10,TACC1,ZNF500,CIC,SUGP2,MFNG,GMFB,CIRBP,MTMR6,ARID1A,SOX4,MACF1,RHOT2,SLC50A1,MAT2A,POLR2A,RAD54B,UTP20,ZNF862,FBXO41,NEK1,POLE,AGPAT2,CHD3,APPL2,DEF6,CWC25 |
| 1.304e-04 | -8.94 | GSE5589_WT_VS_IL6_KO_LPS_AND_IL10_STIM_MACROPHAGE_45MIN_UP | MSigDB lists | GSE5589_WT_VS_IL6_KO_LPS_AND_IL10_STIM_MACROPHAGE_45MIN_UP | 183 | 47 | 17377 | 2626 |
PKP4,DDX47,HJURP,SF3B1,CHTF18,DBF4,LAGE3,TPX2,NDUFA4,UBQLN2,SUPT7L,SNAPC4,PARK7,WWP2,VAV1,CCP110,PPCDC,EI24,KIF22,UPF2,KNTC1,CITED2,SGCB,PDLIM2,RHOA,TK1,RAD51AP1,ERLIN1,BRCA1,CYFIP2,PRKRA,GLOD4,RDH11,KIF18A,KIF18B,POLE,UEVLD,TONSL,CDCA5,NRM,SCARB1,TMEM101,CENPT,GEN1,ESPL1,DDB1,FAM72A |
| 1.304e-04 | -8.94 | GSE22601_DOUBLE_POSITIVE_VS_CD8_SINGLE_POSITIVE_THYMOCYTE_DN | MSigDB lists | GSE22601_DOUBLE_POSITIVE_VS_CD8_SINGLE_POSITIVE_THYMOCYTE_DN | 183 | 47 | 17377 | 2626 |
MZT1,GOLIM4,H2AFZ,UGP2,SESTD1,DAP,FAM129A,CHD1L,TPX2,HAUS4,LMNA,RFWD3,DECR1,AP3S2,ZBTB22,ANAPC7,C12orf75,MSH6,TACC3,SLC25A1,LDHB,TOP3A,ILF3,CDC6,BRCA1,USP22,GSTCD,BORA,KIF11,ASF1B,YIF1A,MTMR3,VEZF1,DSN1,HNRNPR,NEIL3,PTER,NFIL3,PQBP1,FKBP5,KPNA2,CHEK2,GAS2,NANP,NGLY1,RTN3,AAAS |
| 1.304e-04 | -8.94 | GSE5589_UNSTIM_VS_45MIN_LPS_AND_IL10_STIM_MACROPHAGE_UP | MSigDB lists | GSE5589_UNSTIM_VS_45MIN_LPS_AND_IL10_STIM_MACROPHAGE_UP | 183 | 47 | 17377 | 2626 |
UBL3,CDS2,GGA1,SCYL1,PMS2,UCK1,LANCL1,MAP1LC3B,PAPOLA,NSRP1,LPIN2,H2AFY,ATG13,TAP2,SLC26A2,SAP30L,POC5,HTRA2,NIPSNAP1,SRPK2,LDHB,PDPK1,BRD4,GUK1,MAPKAPK3,SNRPB,ZMYND11,EMB,MPG,PSMB9,PEF1,RPS9,MAP2K2,RAB2B,MAPK3,SOCS7,HLA-B,DNAJC10,STAT6,PQBP1,RBMS1,PRPF4,WIPI2,FAU,GLCCI1,CSNK1D,RHEBL1 |
| 1.304e-04 | -8.94 | ZHENG_FOXP3_TARGETS_IN_THYMUS_UP | MSigDB lists | ZHENG_FOXP3_TARGETS_IN_THYMUS_UP | 183 | 47 | 17377 | 2626 |
TCF12,KIF3B,CAST,TRIO,DBF4,TOP2B,DUSP22,ASXL2,ETS1,RAPGEF6,FAM8A1,PIP4K2A,RGS1,MAN1A1,IRF4,ADD3,RABGAP1L,SRI,PARL,TRA2B,MDFIC,NUP153,FAM76B,CNOT6L,CITED2,VOPP1,TNFAIP3,NEK7,CPOX,PSMA1,LNX2,HERPUD2,KLF6,TTC33,ARHGAP15,L3MBTL3,TPP2,NSMCE2,FAM3C,MAP3K5,MYO9A,BTBD10,CDK2,LTA4H,GLCCI1,ZC3HAV1,LRCH1 |
| 1.305e-04 | -8.94 | GSE19772_CTRL_VS_HCMV_INF_MONOCYTES_AND_PI3K_INHIBITION_UP | MSigDB lists | GSE19772_CTRL_VS_HCMV_INF_MONOCYTES_AND_PI3K_INHIBITION_UP | 168 | 44 | 17377 | 2626 |
SRM,USP7,TMEM41B,NUP54,CTCF,EBNA1BP2,CYCS,MYO9B,SLC25A44,BIRC2,RTKN,ABL2,ATP2A2,PPP1R8,AKAP8,RCSD1,DCP1A,PREB,NUDC,SAMD4B,BIRC3,COQ10B,GOPC,MIER2,BMS1,PRPF3,DCUN1D5,ZNF407,CBFB,LSG1,USP36,PPP2CA,ZNF777,SEC23IP,GOLGA2,FBXO28,SYNCRIP,H2AFX,SOCS4,TSTD2,CHPF2,ZBTB11,PPP2R2D,TMEM33 |
| 1.305e-04 | -8.94 | GSE14699_DELETIONAL_TOLERANCE_VS_ACTIVATED_CD8_TCELL_DN | MSigDB lists | GSE14699_DELETIONAL_TOLERANCE_VS_ACTIVATED_CD8_TCELL_DN | 168 | 44 | 17377 | 2626 |
SEPHS2,MRPL42,TMBIM4,NDUFAF2,MDH2,UFC1,UCK2,NUP54,FAM136A,FKBP2,POLR3K,RGS1,FBXO5,CALM2,RPA2,CDKN2C,ERH,TIMM23,SIVA1,TTC9C,KIF22,SYTL3,PPA1,RFC3,PRIM2,PBK,RAD51AP1,PSMA1,CCDC34,DDX39A,ASF1B,HMGN2,RBM47,SURF4,RAD18,DDOST,TMED10,DCK,PSMD8,TIMM17A,TFDP1,DBI,TAF12,PGAM1 |
| 1.305e-04 | -8.94 | ITCH (itchy E3 ubiquitin protein ligase) | protein interactions | 83737 | 176 | 48 | 17029 | 2761 |
UBE2D3,PDCD6IP,CYLD,ATXN3,EWSR1,SCAMP3,CSNK2A1,PRKACA,BECN1,STAM,WDR48,CFLAR,USP5,WWP2,MDM2,PCNA,SNX18,MAVS,TP53BP2,LDLRAD3,GNAI2,SMARCE1,UBE2M,PABPC1,DVL2,PCBP2,RPAP3,KLF10,WBP2,GBA,CUL3,DDX20,ARID1A,ADRB2,WBP1,TOLLIP,SH3GLB1,POLR2A,HGS,SMAD2,ARRDC1,SARAF,KPNA2,DVL1,NCOA1,ARRB2,NUMB,USP13 |
| 1.305e-04 | -8.94 | GPN1 (GPN-loop GTPase 1) | protein interactions | 11321 | 65 | 23 | 17029 | 2761 |
RPAP3,POLR2G,CUL3,CSNK2A1,AGFG1,BRCA1,CCT8,POLR2A,WDR48,WWP2,HSPBP1,POLR2J,PPME1,MBD2,XPA,EFTUD2,OGT,RPAP1,XRCC3,KPNA2,TCOF1,RPRD1B,DDB1 |
| 1.305e-04 | -8.94 | SRSF6 (serine and arginine rich splicing factor 6) | protein interactions | 6431 | 65 | 23 | 17029 | 2761 |
CYLD,EWSR1,SUZ12,RNPS1,SREK1,CUL1,SRSF5,SF3A2,APP,SRSF1,CAND1,SUB1,EIF4A3,SRSF4,TRA2B,TARDBP,SRSF3,RBBP4,TERF1,LUC7L2,TERF2,SRSF10,SRPK2 |
| 1.305e-04 | -8.94 | SEH1L (SEH1 like nucleoporin) | protein interactions | 81929 | 65 | 23 | 17029 | 2761 |
PPP1R37,NDC1,NUP188,MIOS,RAE1,DCTN2,ATP6V0A1,RANGAP1,NUP155,UBE2I,BECN1,NUP205,RPA1,RPA2,NUP210,WDR59,NUP107,NUP153,GLE1,NUP85,AAAS,IFI16,CDC5L |
| 1.305e-04 | -8.94 | MRPL11 (mitochondrial ribosomal protein L11) | protein interactions | 65003 | 65 | 23 | 17029 | 2761 |
DDX28,MRPL9,CYLD,MRPL42,MRPL39,MRPL12,TUFM,ILF3,CUL3,CUL1,MRPL16,ORC1,MRPL19,APP,CAND1,MRPL50,MRPL2,GRSF1,ZNF746,MPV17,MRPL40,MRPL13,MRPL32 |
| 1.305e-04 | -8.94 | SRP68 (signal recognition particle 68) | protein interactions | 6730 | 65 | 23 | 17029 | 2761 |
SRP72,KDM3B,USP7,NIFK,STAU1,NOP2,CUL3,GTPBP4,ELP4,EBNA1BP2,BRCA1,SND1,MCM2,CAND1,KIF5B,PA2G4,CDC27,RBM34,ZNF746,DDX31,FTSJ3,IFI16,CDC5L |
| 1.308e-04 | -8.94 | GSE11864_CSF1_VS_CSF1_PAM3CYS_IN_MAC_UP | MSigDB lists | GSE11864_CSF1_VS_CSF1_PAM3CYS_IN_MAC_UP | 173 | 45 | 17377 | 2626 |
CYTIP,GOLPH3L,ZFP91,SUMO2,UROD,ALKBH5,ARGLU1,DOCK11,DUSP22,TCF19,AP3S2,SSBP3,SLC44A1,FAM76B,TACC3,ABCC5,SRPK2,SPTAN1,KDM3B,ERMP1,EID1,C16orf72,GOPC,RAD51AP1,GNG7,ATP6V0A1,WDR81,EDEM2,KDM3A,NDRG3,MYO1F,VEZF1,FBXO41,PCM1,QARS,STK38,CORO1C,NAGLU,CAB39,TRIM52,WDR91,RTN3,DCAF5,CBX4,EGLN1 |
| 1.308e-04 | -8.94 | GSE14769_UNSTIM_VS_120MIN_LPS_BMDM_UP | MSigDB lists | GSE14769_UNSTIM_VS_120MIN_LPS_BMDM_UP | 173 | 45 | 17377 | 2626 |
ZBED3,C1orf74,PPIB,RAB14,PRKAB1,PPCS,C19orf53,MRPS2,PHF23,KIAA0232,CERK,AP3M2,DHX8,NHLRC3,S1PR2,ATP6V1B2,RCOR3,PITHD1,TRIM65,MBD4,CRKL,MOAP1,USF1,ZBTB45,FAM89B,NDUFS8,CNN2,ZNF770,CAMK2G,TIMP2,CREG1,MBLAC2,EHMT1,VDAC1,STX16,RAD54B,SDHB,MTMR3,MRPL27,APPL2,ZRANB2,ZFP90,MRFAP1L1,DYNC1LI2,RHEBL1 |
| 1.308e-04 | -8.94 | GO_GOLGI_ASSOCIATED_VESICLE | MSigDB lists | GO_GOLGI_ASSOCIATED_VESICLE | 78 | 25 | 17377 | 2626 |
RAB14,TMED7,COPA,ADAM10,GOPC,COPE,SCYL1,CHIC2,PACS1,TGOLN2,TMED3,ARF1,SYNRG,COPG2,SPPL2B,COPB2,SPPL2A,NUCB1,RAB8A,TMED10,ZDHHC13,AP1S1,CLTB,TMED2,KDELR1 |
| 1.311e-04 | -8.94 | MARK4 (microtubule affinity regulating kinase 4) | protein interactions | 57787 | 57 | 21 | 17029 | 2761 |
USP7,CYFIP1,PRKAA1,KCTD20,MYH9,SMARCA4,CYFIP2,MARK2,USP21,PRNP,HGS,HSPA4,CDC42,ODF2,MYO18A,MAP4,ARHGEF2,YWHAZ,STK11,YWHAH,TUBB |
| 1.313e-04 | -8.94 | regulation of transferase activity | biological process | GO:0051338 | 995 | 193 | 17256 | 2622 |
CCNC,FGFR1OP,TXN,TSC2,MAP3K7CL,NF1,CCNL2,CCNB1,UBE2I,S1PR2,MAPK14,PARK7,ZER1,PRNP,CALM2,CDK5,CDKN2C,RAP1A,PIK3R2,CDC25B,MLST8,CDC37,PLK1,COPS8,BAK1,NCK1,GMFB,MRNIP,CDC6,TOPORS,LRP5,UBE2V1,AURKB,DCUN1D5,RFC2,MAP3K4,HHEX,RPS27A,LIMK1,AXIN1,SOCS4,CAB39,ADAM9,STK11,CLU,DVL1,POT1,PDCD4,HSPH1,CLSPN,GMFG,GORASP1,CHTF18,GADD45G,VAV2,PRKAA1,CIB1,LAMTOR3,RGS2,PSEN1,PARN,VPS25,TFAP4,RB1,TIGAR,FBXO7,MDFIC,PIK3IP1,MVP,MCPH1,GNAI2,SOCS5,MAPKAPK3,LDB1,GTPBP4,GBA,KRAS,MAP4K3,ADRB2,MAP2K2,XRCC5,TSC1,MBIP,GOLGA2,DUSP3,CSK,QARS,NLRC5,NUP62,MAP3K5,NIPSNAP2,ALS2,CDKN2A,BCCIP,KARS,GGNBP2,TRAF7,RAF1,MAGED1,TPX2,DAZAP2,PRKACA,LYN,DUSP22,APP,RPL11,HNRNPA2B1,CRKL,SHC1,RALB,NVL,KIF14,PIN1,ADCY9,SOCS6,CDKN1B,F2R,ABI1,CDK12,DVL2,CHP1,ADCY7,CCT2,PSRC1,RFC3,TAOK1,MAP4K4,ELP4,DNAJA1,PKMYT1,RAB1A,SOCS7,PPP2CA,PPP2R5A,TAB2,RBL1,STK38,CORO1C,GADD45B,RPLP1,MAPK1,LRP8,MIF,RPS2,ZFP91,AKT1S1,DCUN1D4,BLM,MAD2L2,FBXO5,PTPN2,CCNK,FGFR3,PDCD10,PTEN,PTPN11,DUS2,NABP2,H2AFY,FEM1B,ATG13,PTGES3,MAP3K14,PDPK1,TGFB1,TELO2,ADAM17,RHOA,HMGN1,TNFAIP3,NEK7,PARP4,PRKAR1B,JTB,WDR81,MEN1,MARK2,MAPK3,SH3BP5,NEK1,HGS,GPS2,PRDX3,OSBPL8,PKD2,NR2F2,WDR91,CD81,UBE2C,HRAS,TERF1,HIPK3,FAF1 |
| 1.317e-04 | -8.94 | YWHAZ (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta) | protein interactions | 7534 | 425 | 98 | 17029 | 2761 |
CYLD,TSC2,SF3B1,RAF1,KIAA0232,OLA1,MYH9,CUL1,PRKACA,SDHA,APP,PARK7,PABPC4,EDC3,MTMR4,UCHL5,CDKN1B,TRA2B,CDC25B,TP53BP2,EIF5,CFL1,CDC5L,BRD4,ATG9A,ELOA,CUL3,ATXN1,UBE2V1,NFATC2,BRCA1,MCM2,VDAC1,GINS4,EIF3A,CHAF1A,OPTN,MAP3K4,TIMM13,SEC61A1,TAB2,CLK3,LIMK1,STK38,H2AFX,TRIM32,FUS,PTPDC1,CBX4,CSNK1D,PARD3,TUBB,UNK,EWSR1,MAPRE1,FAM53C,PRKAA1,NKD2,KIF23,KLC1,AKT1S1,NCKAP1,CDK11B,CSNK1A1,FOXO3,CDC73,PRPF18,DTL,KIF5B,CLIC4,CWC27,INPP5A,HUWE1,CENPJ,HDAC7,ARHGEF2,COPS7B,LDHB,SAMD4B,CYFIP1,STAU1,HMGN1,RPRD1A,TNFAIP3,KIAA0930,CYFIP2,KIF11,MARK2,HSPA1B,TFEB,TSC1,PCM1,YWHAZ,ATP5F1A,MAP3K5,WDR62,CDK2,YWHAH |
| 1.317e-04 | -8.94 | KIF23 (kinesin family member 23) | protein interactions | 9493 | 61 | 22 | 17029 | 2761 |
PLK1,USP7,RNPS1,RACGAP1,BRCA1,WDR5,SHCBP1,ERC1,MEAF6,MAP3K4,EIF2S2,ATP2A2,LIMK1,CEP55,PRC1,YWHAZ,STK11,TCEA1,YWHAH,MICAL3,IFI16,SMNDC1 |
| 1.321e-04 | -8.93 | GGCNKCCATNK_UNKNOWN | MSigDB lists | GGCNKCCATNK_UNKNOWN | 110 | 32 | 17377 | 2626 |
WDR13,BCL2L1,MCTS1,ERH,DPYSL2,TTC9C,YBX1,GEMIN4,CHTOP,ARID4A,EBAG9,PDLIM2,SOCS5,SLC39A9,MIOS,NASP,FBXO9,SREK1,ARID1A,UBE4B,RAB1A,EIF4G2,MATR3,PATL1,RXRB,HMGN2,BRD2,RPL32,SYNCRIP,LUC7L3,PSMD8,ATP6V0C |
| 1.328e-04 | -8.93 | GSE9946_IMMATURE_VS_MATURE_STIMULATORY_DC_UP | MSigDB lists | GSE9946_IMMATURE_VS_MATURE_STIMULATORY_DC_UP | 129 | 36 | 17377 | 2626 |
WSB2,SARNP,ADD1,PPP1R15B,CHIC2,AP3S1,IL21R,DNAJB9,FBRS,MAT2B,VAV1,CCNK,EIF2S2,NUP210,AXIN2,TTC3,STAT3,ATP6V0D1,SEH1L,SRP72,CDKN2AIP,LNX2,CBFA2T2,SMAP2,CAND1,DDX23,FAS,SH3BP5,CHCHD3,MOSPD3,ADSS,NSA2,TRIM26,STAT6,MAPK6,MBD6 |
| 1.335e-04 | -8.92 | GO_REGULATION_OF_TOR_SIGNALING | MSigDB lists | GO_REGULATION_OF_TOR_SIGNALING | 65 | 22 | 17377 | 2626 |
TELO2,MIOS,TSC2,UBR2,PRKAA1,LAMTOR3,RFFL,FBXO9,RRAGC,AKT1S1,RHEB,EPM2A,TSC1,GNA12,TMEM127,PDCD6,WDR59,ARNTL,FAM83D,STK11,SEH1L,MLST8 |
| 1.335e-04 | -8.92 | PID_RB_1PATHWAY | MSigDB lists | PID_RB_1PATHWAY | 65 | 22 | 17377 | 2626 |
AATF,RAF1,E2F3,SMARCA4,MAPK14,UBTF,PPP2CA,RB1,MDM2,CCNA2,BRD2,E2F4,TFDP1,E2F1,CDKN1B,RBBP4,CDK2,ATF2,E2F2,DNMT1,CBX4,CDKN2A |
| 1.341e-04 | -8.92 | HIPK3 (homeodomain interacting protein kinase 3) | protein interactions | 10114 | 38 | 16 | 17029 | 2761 |
MBD1,GORASP1,ZNF107,SRSF5,UBE2I,FADD,SRSF1,FAS,HNRNPA2B1,MTMR4,SIAH1,SIAH2,TRA2B,NR2F2,CREB1,ARRB2 |
| 1.341e-04 | -8.92 | KAT2A (lysine acetyltransferase 2A) | protein interactions | 2648 | 112 | 34 | 17029 | 2761 |
MAX,RAE1,TCF3,SIRT2,TAF6L,WDR5,SUPT7L,UBE2I,DTL,TAF5L,PTGES3,PCBP2,TACC3,KAT2A,EID1,TACC1,PRKDC,LDHA,WDHD1,USP22,SUPT20H,XRCC5,MBIP,SMAD2,E2F4,H2AFX,E2F1,RBPJ,SMAD1,TAF6,CDK2,SGF29,DDB1,TUBB |
| 1.343e-04 | -8.92 | termination of RNA polymerase II transcription | biological process | GO:0006369 | 69 | 23 | 17256 | 2622 |
SRSF11,CDC40,SARNP,THOC1,SNRPB,SRSF6,RBM8A,RNPS1,SLBP,SRSF5,SNRPD3,DDX39A,SYMPK,SRSF1,PAPOLA,ZNF473,EIF4A3,SRSF4,SNRPG,SRSF3,CPSF4,CHTOP,CSTF1 |
| 1.344e-04 | -8.91 | MODULE_15 | MSigDB lists | MODULE_15 | 351 | 79 | 17377 | 2626 |
TCF12,POLA2,RHOG,SLC2A1,PTTG1,PTP4A3,CSNK2A1,GYG1,LYN,STMN1,BIRC2,MBD4,SSR1,RAB8A,RAP1A,PCNA,TNFAIP8,MTA1,DNM2,CORO1A,EIF5,DNMT1,HTRA2,PRPF19,PLK3,BRD4,HMGN4,LRBA,ARHGDIB,PITPNB,SOX4,MCM2,PSMB9,PRIM1,HHEX,WAS,PTPN7,FKBP5,PPP5C,TFDP2,CLN3,EWSR1,MAPRE1,GMFG,SRGN,UBXN1,PMF1,MAN2B1,RGS2,RAB11A,RGS1,TFRC,MSH2,TTLL12,TMX1,IMPA2,FDFT1,TGFB1,CREG1,MAPKAPK3,PRKDC,ILF3,EMP3,ITM2A,ADSL,IRF5,RPA1,CBX3,SERTAD2,SYNCRIP,ETS2,ELMO1,NFIL3,LRPPRC,ZMIZ1,CDK2,MRPL3,IFI16,BYSL |
| 1.344e-04 | -8.91 | central_nervous_system-brain-glioma-astrocytoma | COSMIC cancer mutations | central_nervous_system-brain-glioma-astrocytoma | 37 | 15 | 17385 | 2587 |
CDKN2C,FGFR3,NRAS,NF1,PTEN,VHL,CIC,SF3B1,GOPC,PTPN11,KRAS,H3F3A,HRAS,CDKN2A,FUBP1 |
| 1.349e-04 | -8.91 | vacuolar acidification | biological process | GO:0007035 | 22 | 11 | 17256 | 2622 |
ATP6V0B,CLIC4,PPT1,ATP6V0A2,ATP6V0A1,ATP6V0C,CLN3,CLN6,ATP6V0D1,ATP6V0E1,SNAPIN |
| 1.359e-04 | -8.90 | NAP1L1 (nucleosome assembly protein 1 like 1) | protein interactions | 4673 | 130 | 38 | 17029 | 2761 |
COX15,CYLD,TPX2,MYH9,RPL15,CUL1,CSNK2A1,QSOX2,RPL11,MED10,HUWE1,RPL17,NAP1L4,DCTN1,ASPM,CUL3,RPL6,CAPZA2,BRCA1,CDC23,VDAC1,MCM2,EIF3H,SUPT16H,CAND1,MAGED2,GNAS,NAP1L1,FNTA,H2AFX,FUS,RBBP4,CDK2,ARRB2,TERF1,POT1,PDCD4,SSRP1 |
| 1.360e-04 | -8.90 | UBE3A (ubiquitin protein ligase E3A) | protein interactions | 7337 | 181 | 49 | 17029 | 2761 |
UBE2D3,TSC2,ACTR3,UBXN1,MYH9,UBQLN2,TCF19,RMI1,APP,TRIM65,NPLOC4,RAD23A,CALM2,MDM2,UCHL5,TBC1D14,ZNF746,RAD23B,BTF3L4,CDKN1B,TNPO3,TTC3,COPS7B,TALDO1,PDIA6,LRSAM1,PHKG2,KDELR1,TXNL1,METTL1,EID1,ATG9A,ASPM,NSUN2,WBP2,ARHGDIB,BRCA1,PRDX1,HSPA4,PSMD3,MAPK6,ARNTL,PML,E2F1,YWHAZ,ACTB,PSAP,COPS6,PSMC1 |
| 1.362e-04 | -8.90 | TRAF3 (TNF receptor associated factor 3) | protein interactions | 7187 | 121 | 36 | 17029 | 2761 |
OTUD5,USP7,EWSR1,FAM53C,IRF3,WDR5,UBE2I,SEC16A,BIRC2,CFLAR,SAR1A,ETV6,TANK,MAVS,CREB1,MAP3K14,TFG,TRIM14,ABCC1,PPP3CA,USO1,BIRC3,GALC,ZMYND11,NFATC2IP,AZI2,ECH1,FAS,OPTN,SNAP29,PPP3R1,NUP62,TICAM1,MAP3K5,SMURF1,TRAF5 |
| 1.362e-04 | -8.90 | CNTROB (centrobin, centriole duplication and spindle assembly protein) | protein interactions | 116840 | 121 | 36 | 17029 | 2761 |
PDCD6IP,CYLD,LUZP1,CNOT11,SCYL2,CDC73,CNOT3,DNAJC8,RAB35,KIF14,BANF1,ZNF326,TP53BP2,MTPN,ZNF800,PLK1,ADSL,ATP5MF,SMAP2,CIP2A,ECH1,GIGYF1,SUPT16H,CNOT9,NSA2,MAP3K4,RAB18,SPATA2,TAB2,CCDC14,EXOC4,SMG9,BTF3,CDK2,PDCD2L,SSRP1 |
| 1.374e-04 | -8.89 | V$E2F_Q3_01 | MSigDB lists | V$E2F_Q3_01 | 219 | 54 | 17377 | 2626 |
POLA2,H2AFZ,ZCCHC8,RAB11B,TRMT6,SMC6,CTCF,STMN1,ASXL2,FBXO5,PCNA,SMC3,INTS7,PPP1R8,PELO,PDS5B,TNPO2,NUP153,PCYT2,CITED2,ANKHD1,DNMT1,ARID4A,PPP1R9B,NASP,ERF,PRKDC,E2F3,SREK1,FBXO9,RTF1,CDC6,NUP155,NFATC2IP,SMC2,PKMYT1,MCM2,KDM3A,SRSF1,DDX17,HMGN2,EIF3K,TRIM47,ATAD2,DCK,ZNF367,LUC7L3,NDUFA11,KBTBD7,E2F1,ATE1,WDR62,SASS6,GEN1 |
| 1.375e-04 | -8.89 | regulation of intracellular protein transport | biological process | GO:0033157 | 223 | 55 | 17256 | 2622 |
UBE2D3,TXN,TM9SF4,PRKAA1,ANK3,RAB23,CIB1,NUP54,PRKACA,SEC16A,MAPK14,PSEN1,BCAP31,PARK7,PRNP,MIEF1,KIF5B,CDK5,PDCD10,MDM2,SP100,HUWE1,PIK3R2,PTPN11,GTSE1,PARL,ATG13,MDFIC,MAVS,LMAN1,ZC3H3,HTRA2,CHP1,TGFB1,PLK3,GCC2,ATP5IF1,AKT2,RANGAP1,NUTF2,EDEM2,TRIM28,USP36,SH3GLB1,IWS1,NUCB1,PCM1,OAZ2,NUP62,RUFY3,MAPK1,NUP58,C2CD5,OAZ1,SVIP |
| 1.375e-04 | -8.89 | Rev-mediated nuclear export of HIV RNA | REACTOME pathways | R-HSA-165054 | 34 | 15 | 10287 | 1696 |
NDC1,NUP188,NUP210,RAE1,NUP107,NUP54,NUP62,NUP153,NUP155,RANGAP1,NUP85,NUP58,SEH1L,AAAS,NUP205 |
| 1.376e-04 | -8.89 | myeloid leukocyte mediated immunity | biological process | GO:0002444 | 514 | 109 | 17256 | 2622 |
RHOG,ADA2,RAB14,KMT2E,ADAM10,DYNLL1,RAC1,HEXB,NIT2,NHLRC3,GYG1,MAPK14,LYN,KCMF1,CMTM6,CPNE3,PA2G4,RAP1A,PSMD1,AP1M1,BRI3,TMBIM1,GM2A,KCNAB2,ENPP4,CPNE1,CCT2,TIMP2,NRAS,RAB7A,ARHGAP45,PPIE,CYSTM1,PSMB7,ATP6V0A1,RAB5B,TOLLIP,ALDH3B1,DSN1,AGPAT2,DDOST,SURF4,RAB24,PSMD3,CAB39,CANT1,ATP6V0C,ROCK1,PDXK,LTA4H,MAPK1,CAPN1,TUBB,SVIP,MIF,DNAJC5,GMFG,MANBA,PDAP1,LAMTOR3,B4GALT1,ASAH1,CDK13,MAN2B1,RAB6A,PSEN1,TMEM179B,GNS,CD59,PSMD2,CTSS,ARPC5,HUWE1,OSTF1,CNN2,MVP,LPCAT1,SPTAN1,CYFIP1,FTL,MLEC,RHOA,ADAM17,CREG1,WDR1,HEBP2,C1orf35,PKM,ARMC8,CCT8,NEU1,HSPA1B,PI4K2A,CAND1,XRCC5,CAT,RAB18,ATP6V1D,MAGT1,GOLGA7,SNAP29,SNAP23,ACLY,PGRMC1,IMPDH1,CTSA,PSAP,GPI,PGAM1 |
| 1.385e-04 | -8.88 | ovary-carcinoma-undifferentiated_carcinoma | COSMIC cancer mutations | ovary-carcinoma-undifferentiated_carcinoma | 41 | 16 | 17385 | 2587 |
GNAS,FGFR3,RB1,DNMT3A,NRAS,TSC2,NF1,PTEN,SMARCA4,KRAS,BRCA1,ARID1A,SMAD4,HRAS,CDKN2A,MSH6 |
| 1.392e-04 | -8.88 | PSMD9 (proteasome 26S subunit, non-ATPase 9) | protein interactions | 5715 | 99 | 31 | 17029 | 2761 |
CCDC93,PPP3CA,MAX,H2AFZ,RPRD1A,GNPDA1,AKT2,TCF3,HNRNPF,RCOR1,NUF2,BRCA1,UBE2I,TWF2,GIT2,HMG20A,PSMC4,OIP5,PSMD2,PSMD1,CSK,GRIPAP1,PSMD8,RABGAP1L,PSMD3,ARNTL,YY1,ERI3,AHCYL1,CDK2,PABPC1 |
| 1.396e-04 | -8.88 | rRNA binding | molecular function | GO:0019843 | 60 | 21 | 17224 | 2647 |
NOL12,PPAN,DDX28,RPL8,CIRBP,GTF3A,MRPL16,RPS9,RPL23A,RPL11,UTP25,RPL37,MDM2,RPS14,MRPS27,RPF2,RPL19,RNASEL,RRS1,MRPL11,NSUN4 |
| 1.396e-04 | -8.88 | histone methyltransferase activity | molecular function | GO:0042054 | 60 | 21 | 17224 | 2647 |
ASH1L,KMT2E,SUZ12,CXXC1,EHMT1,NSD3,WDR82,EZH1,MEN1,PRMT2,KMT2C,WDR5,DOT1L,SUV39H2,KMT5C,KMT5A,SETD3,KMT2B,PRMT7,FBL,CARM1 |
| 1.398e-04 | -8.88 | V$E2F1_Q4_01 | MSigDB lists | V$E2F1_Q4_01 | 214 | 53 | 17377 | 2626 |
POLA2,H2AFZ,ZCCHC8,RAB11B,TRMT6,SMC6,CTCF,ASXL2,STMN1,FBXO5,PCNA,SMC3,INTS7,DPYSL2,PPP1R8,PELO,TNPO2,NUP153,PCYT2,ANKHD1,DNMT1,ARID4A,PPP1R9B,NASP,ERF,PRKDC,E2F3,FBXO9,SREK1,NUP155,CDC6,NFATC2IP,PKMYT1,SMC2,MCM2,KDM3A,MAT2A,SRSF1,HMGN2,DDX17,EIF3K,ATAD2,DCK,LUC7L3,ZNF367,NDUFA11,KBTBD7,E2F1,ATE1,RBPJ,WDR62,SASS6,GEN1 |
| 1.405e-04 | -8.87 | REACTOME_RAF_MAP_KINASE_CASCADE | MSigDB lists | REACTOME_RAF_MAP_KINASE_CASCADE | 10 | 7 | 17377 | 2626 |
KRAS,NRAS,MAPK1,MAP2K2,HRAS,RAF1,MAPK3 |
| 1.405e-04 | -8.87 | GO_PROTEIN_PHOSPHATASE_TYPE_1_COMPLEX | MSigDB lists | GO_PROTEIN_PHOSPHATASE_TYPE_1_COMPLEX | 10 | 7 | 17377 | 2626 |
PPP1R11,PPP1R3B,SHOC2,PPP1R9B,PPP1R2,NCK1,PPP1R15B |
| 1.407e-04 | -8.87 | CANX (calnexin) | protein interactions | 821 | 239 | 61 | 17029 | 2761 |
COX15,ATXN3,EWSR1,GXYLT1,PRKCSH,SUZ12,TOR3A,TCF3,SLC2A1,TAP1,MOGS,CSNK2A1,RXYLT1,POMP,SDHA,CDC73,BCAP31,HLA-A,RFWD3,RPA2,RPN1,MDM2,HUWE1,RPN2,CYC1,TECR,LMAN1,PDIA6,ATF2,ABCC1,SPTAN1,STAU1,ATP13A1,SEC61B,PPT1,IDH3A,TUFM,GBA,CUL3,DNAJA1,ADRB2,VDAC1,EDEM2,RAB1A,SERP1,RPA1,CAND1,DERL1,EPRS,KPNA4,DDOST,ITGB1,PGRMC1,PKD2,ST3GAL2,NCLN,CHMP4B,KPNA2,ACADM,CLU,SVIP |
| 1.407e-04 | -8.87 | GO_PROTEIN_DOMAIN_SPECIFIC_BINDING | MSigDB lists | GO_PROTEIN_DOMAIN_SPECIFIC_BINDING | 613 | 126 | 17377 | 2626 |
TCF12,CHMP2A,ST13,ADAM10,DYNLL1,PHRF1,TRIM11,PTTG1,MYH9,CNTROB,BCL2L1,UBE2I,DAZAP2,LYN,APP,REPS1,CALM2,SP100,SH3BP1,KIF14,ETV6,DNM2,MAVS,TP53BP2,DNMT1,DVL2,SRSF10,CDC5L,BAK1,ERCC1,CLCN3,ARHGAP17,AATF,NCK1,EHMT1,CUL3,SLC26A6,DDX20,LNX2,EZR,MCL1,DNAJA1,CADM1,WBP1,CHMP2B,SHCBP1,LUC7L,ERC1,TRIM28,CHAF1A,SOCS7,SRSF1,DPYSL3,CXXC4,HHEX,ATP1A1,WAS,MAFK,AXIN1,E2F4,ITGB1,OGT,ADAM9,STK11,VPS4A,TFDP2,ARRB2,TUBB,DAP,MECP2,STRN4,SDC2,ARFIP2,PAWR,PMF1,RAB6A,LANCL1,PSEN1,VASP,PTEN,INPP5A,CENPJ,MBD2,XPA,FUT8,PTPN11,AXIN2,CTR9,BCL2,OSTF1,CITED2,NCOA2,HNRNPM,ADAM17,LDB1,ACSL3,KRAS,SRSF5,MAP2K2,FADD,DAPK3,HSPA1B,AKAP1,CBX3,SH3BP5,CACNB1,HGS,POLR2J,NSF,CCDC6,ELMO1,ACOX1,TFDP1,STX18,CAPN7,EXOC4,PPP3R1,NUP62,PKD2,HMGB2,CABIN1,YWHAZ,NDE1,IGBP1,YWHAH,FAF1 |
| 1.410e-04 | -8.87 | microtubule binding | molecular function | GO:0008017 | 267 | 64 | 17224 | 2647 |
ZNF207,MYH9,KIF2C,MAP1LC3B,PRNP,DST,KIFC1,CDK5,ABRAXAS2,DPYSL2,KIF14,DNM2,KIF22,MAST2,OGG1,DCTN1,CHP1,PLK1,MAPRE2,PSRC1,TUBGCP5,KIF15,EZR,NUSAP1,EML4,KRIT1,KIF2A,KIF18B,MAP4,MYO18A,GAS2,PPP5C,REEP4,KIF3B,MAPRE1,RAE1,KIF23,RACGAP1,MYO9B,TUBGCP2,RAB11A,NEIL2,SPAG5,JAKMIP1,KIF5B,STARD9,KIF13B,PRC1,ARHGEF2,MYO5A,CAMSAP1,MACF1,KIF11,MYO1F,HAUS8,KIF18A,FNTA,GOLGA2,BIRC5,LRPPRC,FAM83D,CCDC69,MYO9A,NDE1 |
| 1.416e-04 | -8.86 | GO_POSITIVE_REGULATION_OF_PROTEIN_METABOLIC_PROCESS | MSigDB lists | GO_POSITIVE_REGULATION_OF_PROTEIN_METABOLIC_PROCESS | 1425 | 264 | 17377 | 2626 |
TXN,XIAP,CUL1,CCNL2,CCNB1,PPP1R16B,PARK7,FBXO22,CDK5,CALM2,PSMD1,FIZ1,FNIP2,CDC25B,TIPARP,DNMT1,SENP1,MLST8,PLK3,BAK1,AKT2,TOPORS,DCUN1D5,MAP3K4,BRMS1,RPS27A,PSMD8,AXIN1,ITGB1,OGT,ARRB2,OAZ1,HDAC2,SVIP,HSPH1,CLSPN,GGA1,PHF23,PRKAA1,GADD45G,CYCS,EIF2AK4,PSEN1,PSMD9,METTL3,DDRGK1,TFAP4,FKBP1A,DAPK1,GNAI2,LPCAT1,NSUN4,PABPC1,SOCS5,EIF5A,MAPKAPK3,RB1CC1,ADRB2,PTTG1IP,CYFIP2,ABCF1,MAP2K2,PSMB3,FAS,DERL1,HSPBP1,FNTA,GOLGA2,NSF,CSK,CEBPG,MAP3K5,RNF14,RNF139,ALS2,CDKN2A,ATXN3,RAF1,MAGED1,RAC1,TPX2,MYH9,CREBL2,PRKACA,ANKIB1,APP,TERF2IP,CRKL,SHC1,RALB,MTA1,ADCY9,CDKN1B,ANAPC7,MAVS,RNF19A,CLN6,ADCY7,ANKLE2,PSRC1,TAOK1,WBP2,CIRBP,POLR2D,CUL3,CDCA2,CDC23,RAB1A,PSMB9,SERP1,PPP2CA,CDC16,PPP2R5A,NSMCE2,HIPK2,RPLP1,TICAM1,TRIM32,LRP8,CSNK1D,USP13,NCOR2,ZFP91,FLOT1,MAD2L2,CCNK,PSMD2,PDCD10,PTEN,PTPN11,AXIN2,MAP3K14,PDPK1,TNFAIP3,KAT2A,JTB,ANAPC2,ZP3,PICALM,MARK2,FADD,KEAP1,OAZ2,PML,PSAP,CD81,ESPL1,ANAPC4,CCNC,FAM129A,CSNK2A1,NENF,SIRT2,S1PR2,UBQLN2,MAPK14,BIRC2,FANCI,RAP1A,CDC42,EIF4A3,IL6ST,MTPN,COPS8,PLK1,NCK1,EZR,CDC6,BRCA1,SOX4,PAF1,SOCS4,ADAM9,CAB39,ZNF268,STK11,DVL1,CHEK2,CLU,PSMC1,PPP1R12A,PHB2,GORASP1,DNAJB2,CIB1,NKD2,APOPT1,RHBDD1,RB1,CTR9,RBM3,MDFIC,BCL2,LDB1,GBA,PSMA1,MAP4K3,RTF1,KRAS,MASTL,PSMC4,CDC27,SYNCRIP,RUVBL2,EHD4,RNF114,TRAF7,SUMO2,LYN,DUSP22,BCAP31,PAIP1,USP5,PSMA6,MDM2,KIF14,PIN1,AKAP8,PDCD2,CHTOP,F2R,ABI1,HTRA2,DVL2,TIMP2,BIRC3,POLR2G,PSMA8,RAB7A,PSMB7,EDEM2,TOLLIP,RPS9,TAB2,SCAP,PSMD3,GADD45B,SMURF1,MAPK1,SMAD4,MIF,DAP,PAWR,DCUN1D4,CSNK1A1,FBXO5,FGFR3,IRF4,BRD7,ARHGEF2,STAT3,TGFB1,TELO2,RHOA,ADAM17,PRKAR1B,SYMPK,MAPK3,PDCD6,OSBPL8,PKD2,UBE2C,HRAS,IFI16 |
| 1.421e-04 | -8.86 | ORC6 (origin recognition complex subunit 6) | protein interactions | 23594 | 31 | 14 | 17029 | 2761 |
MCM5,PSPC1,DBF4,CDC6,BICD2,CREB1,MCM2,ORC3,APP,SPAG5,TERF2,RPA1,CDC5L,XRCC5 |
| 1.421e-04 | -8.86 | COPRS (coordinator of PRMT5 and differentiation stimulator) | protein interactions | 55352 | 31 | 14 | 17029 | 2761 |
RPS2,EWSR1,LSM6,MEMO1,LACTB,CIRBP,RPL15,USP39,FBL,ARRB2,CBFB,FOXRED1,GAR1,SMURF1 |
| 1.427e-04 | -8.85 | thyroid-carcinoma-papillary_carcinoma | COSMIC cancer mutations | thyroid-carcinoma-papillary_carcinoma | 112 | 32 | 17385 | 2587 |
SF3B1,KTN1,KIF5B,MRPL50,FGFR3,RB1,PTEN,METTL14,FIZ1,ETV6,PTPN11,TFG,NRAS,ASPM,VHL,AKT2,KRAS,MEN1,EML4,MAP2K2,ERC1,SH3BP5,GNAS,PCM1,AHNAK,CCDC6,EXOC4,STK11,HRAS,SMAD4,AAAS,CDKN2A |
| 1.427e-04 | -8.85 | papillary_carcinoma | COSMIC cancer mutations | papillary_carcinoma | 112 | 32 | 17385 | 2587 |
SF3B1,KTN1,KIF5B,MRPL50,FGFR3,RB1,PTEN,METTL14,FIZ1,ETV6,PTPN11,TFG,NRAS,ASPM,VHL,AKT2,KRAS,MEN1,EML4,MAP2K2,ERC1,SH3BP5,GNAS,PCM1,AHNAK,CCDC6,EXOC4,STK11,HRAS,SMAD4,AAAS,CDKN2A |
| 1.430e-04 | -8.85 | focal adhesion | cellular component | GO:0005925 | 397 | 86 | 18223 | 2701 |
RHOG,PDCD6IP,ADD1,RPLP2,ADAM10,RAC1,ACTR3,ZFYVE21,MYH9,CPNE3,GIT2,GNB2,DST,RAB21,CDC42,DNM2,SENP1,CFL1,PCBP2,CHP1,LAP3,RPL38,EZR,STX16,RPS9,ALKBH6,AHNAK,JAK1,RPS14,CORO1C,LIMK1,ITGB1,RPLP1,ADAM9,ATP6V0C,ACTB,MAPK1,CAPN1,NUMB,PPIB,RPS15,RPS2,PPP1R12A,ANXA6,FLOT1,LAMTOR3,KIF23,SLC4A2,ARF1,NCKAP1,ITGB5,PIP5K1C,CAPN2,CD59,TNS3,FGFR3,VASP,ARPC5,ANXA5,ARHGEF2,RPL19,CNN2,PABPC1,PDPK1,CYFIP1,DCAF6,RHOA,ADAM17,CSRP1,FOCAD,RPL6,RPL8,RPS10,KRAS,PLEC,MAP2K2,RHOB,MAPK3,HSPA1B,CAT,GNA12,SCARB2,PDLIM1,SNAP23,YWHAZ,CD81 |
| 1.432e-04 | -8.85 | GO_TERMINATION_OF_RNA_POLYMERASE_II_TRANSCRIPTION | MSigDB lists | GO_TERMINATION_OF_RNA_POLYMERASE_II_TRANSCRIPTION | 61 | 21 | 17377 | 2626 |
SRSF11,CDC40,SARNP,THOC1,SNRPB,SRSF6,RBM8A,RNPS1,SLBP,SRSF5,SNRPD3,DDX39A,SRSF1,PAPOLA,ZNF473,EIF4A3,SRSF4,SRSF3,SNRPG,CHTOP,CSTF1 |
| 1.435e-04 | -8.85 | Atrx (ATRX, chromatin remodeler) | protein interactions | 22589 | 21 | 11 | 17029 | 2761 |
UBTF,BRWD1,RBX1,IVNS1ABP,KAT7,TOP2B,ORC1,WDR76,CHD1,CBX4,SUPT16H |
| 1.441e-04 | -8.85 | GO_PROTEASOME_COMPLEX | MSigDB lists | GO_PROTEASOME_COMPLEX | 74 | 24 | 17377 | 2626 |
TXNL1,UBQLN4,PSMA8,DNAJB2,UBXN1,PSMB7,PSMA1,SYVN1,PSMD9,PSMB9,PSMB3,PSMC4,RAD23A,PSMD2,PSMA6,IDE,PSMD1,UCHL5,PSMD8,PSMD3,RAD23B,SEL1L,UBE3C,PSMC1 |
| 1.441e-04 | -8.85 | KOKKINAKIS_METHIONINE_DEPRIVATION_96HR_DN | MSigDB lists | KOKKINAKIS_METHIONINE_DEPRIVATION_96HR_DN | 74 | 24 | 17377 | 2626 |
IFRD1,TK1,BIRC3,RRM1,AURKB,MPG,CCNB1,PMVK,MAPK14,RAD54B,EBP,CDK5,GSTK1,CDC42,BIRC5,CEBPG,CANT1,MAP3K14,CDK2,CCNB2,ATF2,DNMT1,OGG1,POLQ |
| 1.441e-04 | -8.85 | GO_TRANSCRIPTIONAL_REPRESSOR_COMPLEX | MSigDB lists | GO_TRANSCRIPTIONAL_REPRESSOR_COMPLEX | 74 | 24 | 17377 | 2626 |
SP3,NCOR2,ETV3,DEPDC1,MTA2,MIER1,DDX20,CSNK2A1,RCOR1,MBD3,RCOR3,APPL1,LIN9,TFAP4,GPS2,CHD3,JAZF1,APPL2,RBBP4,SMARCE1,ARID4A,HDAC2,N4BP2L2,RLIM |
| 1.441e-04 | -8.85 | REACTOME_SIGNALING_BY_SCF_KIT | MSigDB lists | REACTOME_SIGNALING_BY_SCF_KIT | 74 | 24 | 17377 | 2626 |
PDPK1,NRAS,TSC2,AKT2,RAF1,RAC1,KRAS,AKT1S1,LYN,FOXO3,MAP2K2,MAPK3,VAV1,MDM2,PTEN,PIK3R2,STAT1,SOCS6,CDKN1B,CREB1,STAT3,MAPK1,HRAS,MLST8 |
| 1.447e-04 | -8.84 | ZNF512 (zinc finger protein 512) | protein interactions | 84450 | 82 | 27 | 17029 | 2761 |
NOL12,STAU1,NOP2,DDX24,URB2,NOL8,YTHDC2,RPL8,GTPBP4,FXR1,BUD13,BLM,ZNF121,CENPU,RPL32,NVL,RBM34,BBX,NOC2L,DDX31,RRS1,PDCD11,MRM3,FTSJ3,GPATCH4,IFI16,ZBTB24 |
| 1.457e-04 | -8.83 | RBM8A (RNA binding motif protein 8A) | protein interactions | 9939 | 108 | 33 | 17029 | 2761 |
NOP9,SEPHS2,EWSR1,R3HCC1L,SUZ12,RAE1,PDAP1,RBM8A,DHX9,SDE2,APP,BCAP31,RPL11,SF3B2,EIF4A3,RAD23B,RRBP1,UPF2,RBM3,PABPC1,LUC7L2,HNRNPM,SRPK2,MLEC,RNPS1,USP21,RPSA,UPF1,RBMX,RUVBL2,SMG9,C2CD5,IFI16 |
| 1.457e-04 | -8.83 | IARS (isoleucyl-tRNA synthetase) | protein interactions | 3376 | 108 | 33 | 17029 | 2761 |
KARS,COX15,CYLD,FOXM1,MAGED1,HNRNPUL2,RPL15,ATP6V1B2,APP,RPL23A,HNRNPA2B1,GSTK1,MDM2,SHC1,AHSA1,ZNF746,TXLNA,CRY2,STAU1,LARS,VHL,CUL3,RPL38,KRAS,BRCA1,VDAC1,EPRS,PFDN5,C1orf131,SYNCRIP,QARS,MAP4,CDK2 |
| 1.457e-04 | -8.83 | MCM6 (minichromosome maintenance complex component 6) | protein interactions | 4175 | 108 | 33 | 17029 | 2761 |
USP7,MCM10,IVNS1ABP,SF3B1,CDT1,ANK3,DCTN2,DBF4,ATG2B,ORC1,SDHA,SMC3,HUWE1,MCM5,MCMBP,PLK1,MAPRE2,TNFAIP3,POLK,CUL3,PSMA1,BRCA1,MCM2,SOX4,CDK11A,ASF1B,RPA1,TONSL,H2AFX,ACLY,CDK2,CDKN2A,SSRP1 |
| 1.459e-04 | -8.83 | DNA conformation change | biological process | GO:0071103 | 286 | 67 | 17256 | 2622 |
ASH1L,UBN1,CHD1L,CCNB1,CHD1,HNRNPA2B1,OIP5,AKAP8,RAD23B,NOC2L,TOP1MT,RBX1,NUSAP1,SMC2,MCM2,GINS4,ASF1B,CENPU,CHAF1A,RAD54B,PAF1,HHEX,BRD2,RPS27A,CHD3,H2AFX,ANP32E,H3F3A,POT1,NAA60,RECQL,HJURP,MTERF1,PHF23,TWNK,SHPRH,DHX9,CTCF,TOP2B,BLM,NCAPG,XPA,ANP32A,H2AFY,NAP1L4,CENPM,TNRC18,GTF2H2,SMC4,HP1BP3,GINS1,NASP,TSPYL4,HELB,TOP3A,XRCC5,NAP1L1,CDCA5,CABIN1,HMGB2,CENPT,RUVBL2,RBBP4,PURA,IPO4,CDKN2A,DDB1 |
| 1.460e-04 | -8.83 | REACTOME_DOWNSTREAM_SIGNALING_EVENTS_OF_B_CELL_RECEPTOR_BCR | MSigDB lists | REACTOME_DOWNSTREAM_SIGNALING_EVENTS_OF_B_CELL_RECEPTOR_BCR | 92 | 28 | 17377 | 2626 |
PDPK1,NRAS,TSC2,PSMA8,AKT2,PSMB7,PSMA1,CUL1,KRAS,AKT1S1,PSMB9,PSMD9,FOXO3,PSMB3,PSMC4,PSMD2,MDM2,PSMA6,PSMD1,PTEN,RPS27A,PSMD8,PSMD3,CDKN1B,CREB1,PSMC1,HRAS,MLST8 |
| 1.462e-04 | -8.83 | GO_POSITIVE_REGULATION_OF_MITOTIC_CELL_CYCLE | MSigDB lists | GO_POSITIVE_REGULATION_OF_MITOTIC_CELL_CYCLE | 120 | 34 | 17377 | 2626 |
UBE2E2,GORASP1,PHB2,CCNB1,BECN1,RAB11A,APP,FBXO5,RB1,MDM2,PTEN,PTPN11,H2AFY,CDC25B,PLK1,TGFB1,BRD4,CUL3,CDC6,NUSAP1,LRP5,USP22,RAB1A,RAD51C,GOLGA2,DUSP3,BIRC5,NSMCE2,CDCA5,XRCC3,UBE2C,GEN1,ESPL1,TERF1 |
| 1.475e-04 | -8.82 | vesicle organization | biological process | GO:0016050 | 334 | 76 | 17256 | 2622 |
RAB14,CHMP2A,PDCD6IP,VTI1A,TAP1,AGFG1,SEC16A,STAM,ANKRD28,RAB8A,SAR1A,PPP6C,AP1M1,DNM2,TAP2,CORO1A,LMAN1,RNF26,TFG,F2R,SNX8,CLCN3,USO1,RAB7A,CUL3,MCFD2,RAB1A,CHMP2B,STX16,PEF1,RAB5B,RAB22A,CHMP4A,TMED10,MYO18A,CHMP4B,VPS4A,ABCA1,C2CD5,CSNK1D,GOLPH3L,GORASP1,SRGN,NKD2,RAB11A,VPS25,FBXO5,CD59,SNX18,SEC24C,BCL2,CREB1,PPP6R1,SYTL3,TMED2,PREB,TRAPPC9,SNX2,GOSR1,PICALM,PI4K2A,SEC31A,TMEM127,SEC23IP,PDCD6,HGS,GOLGA2,NSF,SNAP29,SNAP23,TBPL1,PPP6R3,CHMP7,UNC13C,ALS2,SNAPIN |
| 1.477e-04 | -8.82 | SEIDEN_ONCOGENESIS_BY_MET | MSigDB lists | SEIDEN_ONCOGENESIS_BY_MET | 83 | 26 | 17377 | 2626 |
SRP72,FAM208B,DPM1,ACTR3,ZBED5,RRM1,ARHGEF12,NCKAP1,COMMD8,SERP1,PAPOLA,CSDE1,NSA2,MBIP,SUB1,HSPA4,CLIC4,PTEN,CERS6,GRSF1,STAT1,CAPZA1,ADAM9,TCEA1,EIF5,TMX1 |
| 1.485e-04 | -8.82 | REACTOME_TRANSPORT_TO_THE_GOLGI_AND_SUBSEQUENT_MODIFICATION | MSigDB lists | REACTOME_TRANSPORT_TO_THE_GOLGI_AND_SUBSEQUENT_MODIFICATION | 33 | 14 | 17377 | 2626 |
SEC31A,B4GALT5,SEC24C,FUT8,B4GALT1,MCFD2,B4GALT4,ST8SIA2,B4GALT3,LMAN1,MGAT5,B4GALT2,PREB,MAN1A1 |
| 1.486e-04 | -8.81 | B Cell Receptor Signaling Pathway | WikiPathways | WP23 | 98 | 30 | 5312 | 837 |
PDPK1,PTPN18,MAX,NCK1,RAF1,RPS6KA1,RAC1,VAV2,E2F3,NFATC2,MEF2D,ELK1,LYN,MAPK14,ETS1,MAP2K2,PIP5K1C,VAV1,CRKL,IRF4,NFATC3,CDC42,SHC1,PIK3R2,PTPN11,CREB1,MAPK1,CD81,ATF2,HRAS |
| 1.488e-04 | -8.81 | IKZF1 (IKAROS family zinc finger 1) | protein interactions | 10320 | 117 | 35 | 17029 | 2761 |
RMND5A,MIB2,NCOR2,ANKRD27,POC1A,CDK2AP2,SMARCA4,UBE2I,GLRX3,MAD2L2,NEK6,HDAC7,PIN1,MTA1,AP1M1,SPATC1L,SMARCE1,MKLN1,FOXK1,GALC,MTA2,PSMA1,NFATC2,FAM50B,ARMC8,BTBD1,CHD3,CSNK1G1,C1orf109,AEN,WDR76,RBBP4,BYSL,HDAC2,RAD51D |
| 1.489e-04 | -8.81 | Regulation of APC/C activators between G1/S and early anaphase | REACTOME pathways | R-HSA-176408 | 81 | 27 | 10287 | 1696 |
PLK1,PSMA8,PSMB7,PSMA1,CUL1,ANAPC2,CDC23,CCNB1,PSMD9,PSMB9,PSMB3,PSMC4,FBXO5,PSMD2,PSMA6,CCNA2,CDC16,PSMD1,CDC27,RPS27A,PSMD8,PSMD3,ANAPC7,CDK2,UBE2C,PSMC1,ANAPC4 |
| 1.489e-04 | -8.81 | GSE22886_NAIVE_CD4_TCELL_VS_NKCELL_DN | MSigDB lists | GSE22886_NAIVE_CD4_TCELL_VS_NKCELL_DN | 189 | 48 | 17377 | 2626 |
SEPHS2,TCF12,FEZ2,GGNBP2,MUT,TRIP12,RAC1,UCK2,BLM,DUSP22,BIRC2,COPB2,NRF1,MED8,PPP1R8,SEC24C,PHTF1,RAD23B,GMEB1,NUP107,CTR9,KIFAP3,ZNF226,TARDBP,AQR,CDK12,ENPP4,ABHD2,TIMM8B,MLEC,ASPM,NEK7,PSPC1,ACSL3,NARF,WIPF1,ARHGEF12,GALNT7,RHBDF2,KRIT1,DDX23,PON2,KEAP1,SNAP29,HIPK2,SEL1L,MRFAP1L1,TRAF5 |
| 1.489e-04 | -8.81 | GSE17721_LPS_VS_POLYIC_6H_BMDC_DN | MSigDB lists | GSE17721_LPS_VS_POLYIC_6H_BMDC_DN | 189 | 48 | 17377 | 2626 |
MRPL39,TOR3A,UBXN1,HEXB,CIB1,KLC1,PIP5K1C,ARHGEF1,PDCD2,RPL19,CORO1A,AQR,PLCL2,ALDH18A1,TMEM14C,KCNAB2,CDC37,GINS1,PRIM2,CIC,NSDHL,RAB7A,LACTB,POLR3GL,WIPF1,PSMG1,HTATIP2,PLEC,PRMT2,KDM3A,RFC2,PLEKHF2,TFEB,SCARB2,WAS,DHX16,CCDC6,STK38,CORO1C,EXOC4,MBOAT1,HMGB2,KLHDC4,PDXK,RUFY3,TOB1,AAAS,SNAPIN |
| 1.489e-04 | -8.81 | GSE41867_DAY6_VS_DAY8_LCMV_ARMSTRONG_EFFECTOR_CD8_TCELL_UP | MSigDB lists | GSE41867_DAY6_VS_DAY8_LCMV_ARMSTRONG_EFFECTOR_CD8_TCELL_UP | 189 | 48 | 17377 | 2626 |
CTDP1,GALK1,CMAS,SMAP1,TMEM203,EYA1,GNE,TMEM97,SLC35B1,GYG1,BZW2,KTN1,RSAD1,MFSD10,FANCL,RAP1A,GRSF1,IL6ST,MBD2,UBA5,SLC44A1,TAF5L,RNASEH2A,MYBL1,ANKLE2,CLCN3,MAPRE2,ELL2,TMEM39A,GALC,MAN1B1,SSR2,ATXN1,MRPS14,FAS,CAT,KIF2A,DERL1,ZNF180,GALNT2,RPL32,ACYP1,STT3A,ZNF330,QARS,H2AFX,SEL1L,TATDN1 |
| 1.489e-04 | -8.81 | GSE22935_UNSTIM_VS_12H_MBOVIS_BCG_STIM_MACROPHAGE_UP | MSigDB lists | GSE22935_UNSTIM_VS_12H_MBOVIS_BCG_STIM_MACROPHAGE_UP | 189 | 48 | 17377 | 2626 |
RECQL,UGP2,GNPDA1,IVNS1ABP,SLC41A1,BABAM1,SNX15,HABP4,DHX8,PXMP2,GGA2,PSEN1,SDHA,VPS25,DDRGK1,HDAC7,SLC35B4,ANXA5,LTN1,AQR,NUDC,EBAG9,NTPCR,CYTH1,MAPRE2,NET1,TYW1,KIAA0930,TUFM,SEPT8,BOLA1,CBFA2T2,TAZ,POLR2A,RPA1,ADSS,TMEM184C,PLD3,ZNF282,ATP6V1D,ORMDL2,TULP3,SIL1,ATF6,CTSA,IDH3B,ATMIN,TMEM33 |
| 1.489e-04 | -8.81 | GSE22140_GERMFREE_VS_SPF_MOUSE_CD4_TCELL_DN | MSigDB lists | GSE22140_GERMFREE_VS_SPF_MOUSE_CD4_TCELL_DN | 189 | 48 | 17377 | 2626 |
NCOR2,EWSR1,TMEM184B,NQO1,AP1B1,GGA2,ABHD14A,BCAP31,RGS1,LMNA,CD59,CAPN2,RPN1,APLP2,VASP,SAR1A,RAB35,RPN2,TP53BP2,TECR,PDIA6,CDC37,PPIF,CCT2,TIMP2,SNX2,ELL2,MAP4K4,SLC16A7,CAMSAP1,EMP3,PLEC,VDAC1,AKAP1,PI4K2A,SH3BP5,TPD52L2,SGSH,SERTAD2,AHNAK,ERGIC3,YWHAZ,PRPF4,PDXK,ARRB2,YWHAH,FUBP1,PTOV1 |
| 1.489e-04 | -8.81 | GSE339_CD4POS_VS_CD8POS_DC_DN | MSigDB lists | GSE339_CD4POS_VS_CD8POS_DC_DN | 189 | 48 | 17377 | 2626 |
SLC12A7,TXN,CASP6,MRPS15,ARID2,AGPAT3,SUMF1,SYNRG,REEP5,KCMF1,PDXDC1,PHC2,FKBP1A,RPN1,NEK6,THAP4,RPN2,CLDND1,CYB5R1,LRRC59,PPA1,USO1,SEC61B,CREG1,NET1,NSDHL,KRTCAP2,ODC1,MAT2A,PI4K2A,KIF2A,CAT,DNAJC10,SCARB2,PDCD6,SMAD2,AHNAK,SEC61A1,TXNDC16,DDOST,ACYP1,NIP7,HIPK2,PGAM1,SLC25A39,PFKP,VPS29,PTOV1 |
| 1.489e-04 | -8.81 | GSE9037_WT_VS_IRAK4_KO_LPS_4H_STIM_BMDM_UP | MSigDB lists | GSE9037_WT_VS_IRAK4_KO_LPS_4H_STIM_BMDM_UP | 189 | 48 | 17377 | 2626 |
HIVEP3,NDUFS1,EIF3D,TAP1,CHIC2,ARF1,OAT,SNN,SUPT7L,SLC20A1,ETS1,KCMF1,TMEM161B,SLC25A37,MRPL50,MDM2,CLIC4,EIF2S2,TIMM23,MECR,NAP1L4,ZRANB1,ATF2,F2R,ZNF800,KDELR1,TIMM50,SAP30,TXNL1,ENPP4,TSHZ1,HMGN5,NCK1,SNRPB,TOR1AIP2,MTMR12,MAK16,APPL1,TWISTNB,UTP20,VEZF1,RAD18,SPATA2,HMGB2,MAPK1,NGLY1,C7orf26,LRCH1 |
| 1.489e-04 | -8.81 | GSE27786_LIN_NEG_VS_CD8_TCELL_UP | MSigDB lists | GSE27786_LIN_NEG_VS_CD8_TCELL_UP | 189 | 48 | 17377 | 2626 |
MRPL42,TMBIM4,PDAP1,TKT,CUL1,SLC29A1,PMF1,SRRT,CUTC,ABHD14A,LYAR,OIP5,FAM192A,FARSA,ZNF449,STRBP,COQ4,PPP1R8,MCM5,PIK3R2,ZDHHC13,TTLL12,LRRC59,TMEM9,TACC3,SLC25A1,CYFIP1,TIMM8B,IDH3A,RAD51AP1,ACSL3,CCDC34,DCTD,CDCA2,CCNF,YIF1A,NUCB1,CDC16,POLE,PPM1G,DBI,DTX4,PML,SMPD4,DMWD,CDK2,GCSH,PTOV1 |
| 1.489e-04 | -8.81 | GSE2770_UNTREATED_VS_IL4_TREATED_ACT_CD4_TCELL_2H_UP | MSigDB lists | GSE2770_UNTREATED_VS_IL4_TREATED_ACT_CD4_TCELL_2H_UP | 189 | 48 | 17377 | 2626 |
DNAJC2,CMAS,PKP4,FOXM1,DAP,MUM1,BABAM1,ARID5A,CDCA8,UBE2Z,TBC1D13,PSEN1,ITGB5,SPAG5,LIN9,CDKN2C,PSMD2,MED10,PHF14,FJX1,DNM2,NDUFB9,ZNF710,EEF1D,ATP6V1G1,GINS1,STAU1,MND1,TRAFD1,TIMP2,CDC123,PBK,TEX10,RNPS1,CKAP2L,CDCA2,EIF2A,ARPC1A,PON2,KIF18A,MTHFD2,NSMCE2,PROSER1,NUP62,NDE1,BEND6,PTDSS1,DCAF5 |
| 1.489e-04 | -8.81 | GSE15330_HSC_VS_MEGAKARYOCYTE_ERYTHROID_PROGENITOR_IKAROS_KO_UP | MSigDB lists | GSE15330_HSC_VS_MEGAKARYOCYTE_ERYTHROID_PROGENITOR_IKAROS_KO_UP | 189 | 48 | 17377 | 2626 |
CHMP2A,NAT9,LZTR1,TXN,SUCLG1,GNPDA1,SEC61G,MUM1,SLC2A1,LAMTOR3,FLOT1,PLAGL2,B4GALT1,AGPAT3,TMED3,POFUT1,APP,UBLCP1,ARF5,ANP32A,CNN2,MAP3K14,TALDO1,ST8SIA2,MVP,TMEM14C,ILKAP,GM2A,MORC3,TSHZ1,TIMP2,FAM49B,LDHA,ARHGDIB,RAB3IP,PLEC,KLF6,TFEB,RAB18,ATP6V1D,PRDX5,PML,SLC25A19,CTSA,FAM126A,CHPT1,ABCA1,SMARCD1 |
| 1.491e-04 | -8.81 | renal_pelvis | COSMIC cancer mutations | renal_pelvis | 16 | 9 | 17385 | 2587 |
FGFR3,NRAS,PTEN,VHL,ETV6,KRAS,HRAS,MSH6,CDKN2A |
| 1.495e-04 | -8.81 | PSMB3 (proteasome subunit beta 3) | protein interactions | 5691 | 95 | 30 | 17029 | 2761 |
PLK1,PSMA8,VHL,CAST,PSMB7,PSMA1,CUL1,PSMG1,POMP,SYVN1,MCM2,PRMT2,PSMB9,PSMB3,PSMC4,RAD23A,FAM192A,KIF5B,PSMD2,PSMD1,PSMA6,KDM2A,UCHL5,PSMD8,PSMD3,FBXO7,H2AFX,CAPZA1,ASNA1,PSMC1 |
| 1.495e-04 | -8.81 | VIPR2 (vasoactive intestinal peptide receptor 2) | protein interactions | 7434 | 95 | 30 | 17029 | 2761 |
NOP9,PIGN,ERMP1,C1orf112,BTAF1,GPR89A,HSDL1,DNAAF5,TBRG4,MTX1,ERBIN,ATP5F1B,XPO7,BZW2,APP,TUBGCP2,CIP2A,EBP,RAB21,TMEM41A,SURF4,CERS6,DAD1,RABGAP1L,PDS5B,TNPO3,MAVS,ATP5F1A,NR2F2,REEP4 |
| 1.495e-04 | -8.81 | CEP120 (centrosomal protein 120) | protein interactions | 153241 | 95 | 30 | 17029 | 2761 |
FGFR1OP,C9orf78,LUZP1,CCDC138,CDC123,CAMSAP1,PSMG1,HAUS4,POMP,CNTROB,CNOT11,RAPGEF6,HAUS2,FANCI,ECH1,HAUS8,NAP1L1,PCM1,CCP110,CENPJ,KIF14,ODF2,CEP55,GPATCH1,BTF3,TP53BP2,NAP1L4,STAT3,MTX2,PDCD2L |
| 1.497e-04 | -8.81 | ORC3 (origin recognition complex subunit 3) | protein interactions | 23595 | 42 | 17 | 17029 | 2761 |
NOP9,PLK1,MCM10,DBF4,KLC1,CDC6,BRCA1,ORC1,QSOX2,APP,XRCC5,MCM5,KIFAP3,ORC3,TACC3,CDC5L,TERF2 |
| 1.497e-04 | -8.81 | Cep55 (centrosomal protein 55) | protein interactions | 74107 | 42 | 17 | 17029 | 2761 |
CHMP2A,GCC2,PDCD6IP,RACGAP1,MAP7D1,IKBIP,ATP6V1B2,CHMP2B,PCBP1,SPAG5,MAGED2,PCM1,FBXO28,PDLIM1,INTS7,CEP55,CHMP4B |
| 1.499e-04 | -8.81 | VPS26C (VPS26 endosomal protein sorting factor C) | protein interactions | 10311 | 15 | 9 | 17029 | 2761 |
CCDC93,COMMD10,XPO7,COMMD6,COMMD4,COMMD8,VPS29,MAPK6,SH3GLB1 |
| 1.499e-04 | -8.81 | POLM (DNA polymerase mu) | protein interactions | 27434 | 15 | 9 | 17029 | 2761 |
UBE2D3,CTU2,PCNA,PTEN,PTTG1,CEP55,KRAS,ACAD8,UBE2C |
| 1.499e-04 | -8.81 | GSE28737_FOLLICULAR_VS_MARGINAL_ZONE_BCELL_UP | MSigDB lists | GSE28737_FOLLICULAR_VS_MARGINAL_ZONE_BCELL_UP | 184 | 47 | 17377 | 2626 |
TMEM106C,MIB2,SLC30A9,NADSYN1,ZNF496,LZTR1,ANXA6,TMEM203,PHB2,CTCF,EZH1,MXD4,PRKACA,LCLAT1,FAM8A1,XPR1,SLC25A37,EBP,ATIC,TBC1D14,CNPY4,MECR,TMEM14C,HDHD2,RHBDD2,PREB,METTL1,PPP1R18,TACC1,HELB,TYW1,SEPT8,GORASP2,SUMF2,MEN1,MAK16,SGSH,TTC13,BRWD1,SCAP,DHX16,HNRNPR,PPA2,MEGF9,DTD1,PDSS2,RAD51D |
| 1.499e-04 | -8.81 | GSE11864_CSF1_VS_CSF1_IFNG_PAM3CYS_IN_MAC_UP | MSigDB lists | GSE11864_CSF1_VS_CSF1_IFNG_PAM3CYS_IN_MAC_UP | 184 | 47 | 17377 | 2626 |
PKP4,TMX4,TGOLN2,IFT27,ITGB5,PITHD1,REPS1,ATPAF1,SAC3D1,PAPOLA,C14orf119,CYHR1,EIF4A3,MEGF8,SSBP3,ADCY9,MAVS,NFU1,SPTAN1,RPAP3,ERMP1,ATP13A1,POLR2G,TIMMDC1,NQO2,OXR1,LDHA,NDRG3,ZDHHC3,PRIM1,XRCC5,UBTF,TMEM127,ALDH3B1,PPP2R5A,TXNDC16,NSF,TMED10,STK38,PRPS2,BBX,OGT,ZDHHC7,ATP6V0C,GPI,IGBP1,RTN3 |
| 1.499e-04 | -8.81 | GSE17721_POLYIC_VS_GARDIQUIMOD_12H_BMDC_DN | MSigDB lists | GSE17721_POLYIC_VS_GARDIQUIMOD_12H_BMDC_DN | 184 | 47 | 17377 | 2626 |
SEPHS2,MMACHC,TP53RK,MUT,SHPRH,SRSF6,BABAM1,HEXB,STARD7,PRKACA,FAM8A1,PNO1,ATP6V0B,SNX18,RNASEK,MECR,MAVS,CYB5R1,AQR,RNF26,LRRC59,SLC35A1,KDELR1,SMC4,FDFT1,DDX24,NOA1,RDH10,PSMG1,MTX1,SEPT7,RHOT1,EIF4G2,LUC7L,API5,MAT2A,BTBD1,UTP20,SERF2,STT3A,ACLY,COX8A,GAS2,PPP5C,AP2S1,DDB1,PDF |
| 1.499e-04 | -8.81 | GSE23502_WT_VS_HDC_KO_MYELOID_DERIVED_SUPPRESSOR_CELL_COLON_TUMOR_UP | MSigDB lists | GSE23502_WT_VS_HDC_KO_MYELOID_DERIVED_SUPPRESSOR_CELL_COLON_TUMOR_UP | 184 | 47 | 17377 | 2626 |
TXN,MDH2,HNRNPUL2,CDCA3,TPX2,RACGAP1,NUF2,PAWR,S1PR2,RGS2,STMN1,SPAG5,PAIP2,CDKN2C,GTPBP3,CCNA2,NEK6,KIFAP3,KNTC1,TAGLN2,CLTB,CITED2,PLK3,CELSR2,KLF10,NCK1,CREG1,PBK,MIER1,MKI67,LDHA,RRM2,CKAP2L,EAF2,ANLN,SHCBP1,ZNF862,BIRC5,CDCA5,HMGB2,TFDP2,UBE2C,CCNB2,YWHAH,CHID1,LONP2,FAM72A |
| 1.499e-04 | -8.81 | GSE33162_HDAC3_KO_VS_HDAC3_KO_MACROPHAGE_DN | MSigDB lists | GSE33162_HDAC3_KO_VS_HDAC3_KO_MACROPHAGE_DN | 184 | 47 | 17377 | 2626 |
ZNF207,TMED7,DNMT3A,ZCCHC9,RWDD1,PHF23,FAM129A,CDCA3,MYO9B,PRPF39,STMN1,ZADH2,TCF19,CRKL,PDCD10,VMP1,ARPC5,MTA1,CDKN1B,MDFIC,MAST2,PTGES3,ARL5A,S100A6,PCBP2,CFL1,TSPAN31,NUDT4,IDH3A,BTG2,MKI67,WDHD1,RRM2,SMC2,KLF6,SH3GLB1,PLEKHF2,ZFR,RPA1,MID1IP1,POLE,TAB2,CAB39,HMGB2,ACTB,ANP32E,SMNDC1 |
| 1.499e-04 | -8.81 | GSE2405_HEAT_KILLED_VS_LIVE_A_PHAGOCYTOPHILUM_STIM_NEUTROPHIL_9H_UP | MSigDB lists | GSE2405_HEAT_KILLED_VS_LIVE_A_PHAGOCYTOPHILUM_STIM_NEUTROPHIL_9H_UP | 184 | 47 | 17377 | 2626 |
HNRNPAB,MDH2,EIF3D,NDUFA4,SIKE1,RGS2,HAUS2,HDDC2,PAPOLA,FERMT3,FBXL6,C18orf32,VMP1,PIN1,PPCDC,ZDHHC13,ARL6IP1,GTF2H2,ATP6V0D1,ARL5A,CDC37,PRPF19,DDX24,SIGMAR1,TSPAN31,LDHA,LNX2,MAK16,TWISTNB,RPL37,EIF3K,BOLA3,HGS,PDCD6,HSPBP1,PPP1R11,COX5A,CANT1,ATP6V0C,CHMP4B,SNRPG,BTF3,AKNA,LTA4H,YWHAH,PGAM1,NUDT3 |
| 1.499e-04 | -8.81 | GSE10273_HIGH_IL7_VS_HIGH_IL7_AND_IRF4_IN_IRF4_8_NULL_PRE_BCELL_UP | MSigDB lists | GSE10273_HIGH_IL7_VS_HIGH_IL7_AND_IRF4_IN_IRF4_8_NULL_PRE_BCELL_UP | 184 | 47 | 17377 | 2626 |
DDX47,TCF3,DBF4,SRRT,PAIP1,FZD6,FASTKD3,ANKLE1,NRF1,PSMD1,CCP110,EIF4A3,INTS7,LRRC8D,BANF1,BDH1,PRC1,NUP107,GEMIN6,TTC4,GTF2H2,N4BP2,SLC25A1,SAP30,GINS1,HMGN5,ANKRD37,TMEM39A,ERLIN1,KIAA0930,ADSL,BUD13,CCNF,GSTCD,RFC2,STOML2,TRIM47,HSPBP1,RAD18,FAM110A,ARNTL,E2F1,PRPF4,RPS6KC1,CDKN2A,PARD3,ZC3HC1 |
| 1.499e-04 | -8.81 | GSE7852_LN_VS_THYMUS_TCONV_DN | MSigDB lists | GSE7852_LN_VS_THYMUS_TCONV_DN | 184 | 47 | 17377 | 2626 |
TXN,MCM10,C19orf53,DEPDC1,ARID2,RRM1,KIF2C,BLM,AP3S1,ANKRD23,RB1,PCNA,FUT8,RAB4A,PRC1,TIMELESS,PLK1,ATP13A1,KLF10,ANKRD37,PBK,RAD51AP1,CCDC34,FRAT2,ITM2A,CDC6,NUSAP1,SOX4,CCNF,PRKRA,ASF1B,PRIM1,SUPT16H,MASTL,PTPRF,GALNT2,SAFB,CDCA5,C4orf46,CENPT,SASS6,CDK2,RNF14,UBE2C,E2F2,ESPL1,PFKP |
| 1.499e-04 | -8.81 | GSE13229_IMM_VS_INTMATURE_NKCELL_DN | MSigDB lists | GSE13229_IMM_VS_INTMATURE_NKCELL_DN | 184 | 47 | 17377 | 2626 |
GCLM,TM9SF4,POLR2K,PHF23,SHPRH,RAE1,SLC39A13,KLC1,EZH1,DAZAP2,METTL3,COMMD8,FAM8A1,CAPN2,CCP110,DPYSL2,RPN2,TTC4,PDIA6,ABI1,ABCC5,NIPAL3,VOPP1,SEPT9,DCAF8,DDX20,PRKRA,PCGF1,ICAM2,NDRG3,EPB41,TMEM127,PEX5,EIF4ENIF1,PLAA,PPP2R5A,DHX16,FAM126A,ZFP90,NCLN,ACADM,CLN3,SNRNP70,TERF1,ABCA1,ANAPC4,PFKP |
| 1.500e-04 | -8.80 | 5'-3' RNA polymerase activity | molecular function | GO:0034062 | 44 | 17 | 17224 | 2647 |
POLR2I,POLR2G,POLR2L,PRIM2,POLR2K,POLR2D,POLR3GL,POLR3K,TWISTNB,POLR2A,PRIM1,POLR2J,CD3EAP,CRCP,RPAP1,POLR1B,ZNRD1 |
| 1.500e-04 | -8.80 | RNA polymerase activity | molecular function | GO:0097747 | 44 | 17 | 17224 | 2647 |
POLR2I,POLR2G,POLR2L,PRIM2,POLR2K,POLR2D,POLR3GL,POLR3K,TWISTNB,POLR2A,PRIM1,POLR2J,CD3EAP,CRCP,RPAP1,POLR1B,ZNRD1 |
| 1.506e-04 | -8.80 | GSE23321_CENTRAL_VS_EFFECTOR_MEMORY_CD8_TCELL_DN | MSigDB lists | GSE23321_CENTRAL_VS_EFFECTOR_MEMORY_CD8_TCELL_DN | 179 | 46 | 17377 | 2626 |
PPP1R37,THOC1,MRPS2,MUM1,TKT,MEF2A,CUTC,RPL11,DDRGK1,PRKD3,BANF1,XPA,RPAP1,BRD7,SLC27A4,ZBTB22,MARCH2,METTL9,SPTSSA,F2R,POC5,SPSB3,CSTF1,PRPF19,ERCC1,TIMMDC1,FOPNL,DDX20,KRAS,MAP4K3,CDC23,KDM3A,POLG2,RPL36,RPL37,KIF2A,CDC16,HSPB11,SURF4,ACYP1,RAB24,YWHAZ,ACADM,TSEN15,CCDC59,AAAS |
| 1.506e-04 | -8.80 | GSE11864_UNTREATED_VS_CSF1_IFNG_IN_MAC_DN | MSigDB lists | GSE11864_UNTREATED_VS_CSF1_IFNG_IN_MAC_DN | 179 | 46 | 17377 | 2626 |
SEPHS2,ANKRD27,IMMT,NSMCE4A,SEC61G,CDK2AP2,CCM2,XIAP,COMMD5,TMEM165,PMVK,REEP5,GIT2,MAT2B,CTNNBL1,SIAH1,ZNRF2,ATG3,IL6ST,PHTF1,TXLNA,MDFIC,TARDBP,ATP6V1G1,NTPCR,TIMMDC1,RAB7A,USP10,GOSR1,PSMB3,PI4K2A,PALB2,NSF,DHX16,CHCHD1,PSMD3,DBI,SIL1,NUP62,MRFAP1L1,DUSP11,WDR76,PLOD3,RNF14,CD81,ZNF146 |
| 1.510e-04 | -8.80 | GSE9601_UNTREATED_VS_NFKB_INHIBITOR_TREATED_HCMV_INF_MONOCYTE_DN | MSigDB lists | GSE9601_UNTREATED_VS_NFKB_INHIBITOR_TREATED_HCMV_INF_MONOCYTE_DN | 169 | 44 | 17377 | 2626 |
CORO7,ATXN3,GNPNAT1,NF1,MAGED1,AGFG1,DUSP22,ETS1,TMEM161B,SLC25A36,MAT2B,LIN9,IRF4,IL6ST,FJX1,ZDHHC13,EI24,AXIN2,KIFAP3,BCAP29,TTC3,MICAL3,WDR41,YTHDC1,EMB,HELB,MAP4K4,ITM2A,GALK2,CHMP2B,GUF1,XRCC5,MAP3K4,TAF2,CHCHD3,DNAJC10,WDR11,ACOX1,ITGB1,PRMT7,ATF6,PPP6R2,CCDC125,CD81 |
| 1.514e-04 | -8.80 | BIOCARTA_MAL_PATHWAY | MSigDB lists | BIOCARTA_MAL_PATHWAY | 19 | 10 | 17377 | 2626 |
RHOA,CDC42,LIMK1,RAF1,RAC1,ROCK1,MAPK1,HRAS,MAP2K2,MAPK3 |
| 1.516e-04 | -8.79 | PRL | COSMIC cancer mutations | PRL | 13 | 8 | 17385 | 2587 |
GNAS,CDKN2C,RB1,NRAS,KRAS,MEN1,HRAS,CDKN2A |
| 1.516e-04 | -8.79 | pituitary-adenoma-PRL | COSMIC cancer mutations | pituitary-adenoma-PRL | 13 | 8 | 17385 | 2587 |
GNAS,CDKN2C,RB1,NRAS,KRAS,MEN1,HRAS,CDKN2A |
| 1.516e-04 | -8.79 | skin-malignant_melanoma-lentigo_maligna | COSMIC cancer mutations | skin-malignant_melanoma-lentigo_maligna | 13 | 8 | 17385 | 2587 |
NRAS,PTEN,SF3B1,RAC1,KRAS,MEN1,HRAS,CDKN2A |
| 1.516e-04 | -8.79 | cervix-carcinoma-adenocarcinoma | COSMIC cancer mutations | cervix-carcinoma-adenocarcinoma | 13 | 8 | 17385 | 2587 |
FGFR3,NRAS,PTEN,AXIN1,STK11,KRAS,HRAS,CDKN2A |
| 1.518e-04 | -8.79 | GO_REGULATION_OF_MULTI_ORGANISM_PROCESS | MSigDB lists | GO_REGULATION_OF_MULTI_ORGANISM_PROCESS | 451 | 97 | 17377 | 2626 |
CHMP2A,TMEM203,TRIM11,RAC1,YTHDC2,TAP1,ALKBH5,SMARCA4,SIRT2,AP1B1,ELMOD2,CHD1,BIRC2,RAD23A,FANCL,SP100,ZNF639,DNAAF2,AP1M1,AP2B1,TAP2,TARDBP,MAVS,C8orf59,PCBP2,CFL1,TRIM14,SRPK2,TRIM8,POLR2G,POLR2L,BIRC3,SNRPB,RAB7A,PPIE,CRNKL1,POLR2D,ARHGDIB,IL12RB1,CHMP2B,TRIM28,STAT1,AP1S1,CHMP4B,TRIM32,RNASEL,VPS4A,SMURF1,AP2S1,MIF,DDX58,PPIB,CTDP1,MRPS2,POLR2K,CIB1,B4GALT1,EIF2AK4,ARF1,VPS25,RHBDD1,HLA-A,GTF2F1,RFWD3,CCNK,TFAP4,ANXA5,MDFIC,BCL2,LRSAM1,PABPC1,ZNF189,STAU1,POLR2I,TNFAIP3,TMEM39A,ILF3,MRPS10,PACS1,KCNQ1,ZP3,POLR2A,ISG15,MAPK3,DERL1,TRIM26,POLR2J,ELMO1,PML,COX8A,SLC25A19,MDH1,DDX5,PARP10,ZC3HAV1,DDB1,IFI16 |
| 1.521e-04 | -8.79 | GO_REGULATION_OF_VIRAL_TRANSCRIPTION | MSigDB lists | GO_REGULATION_OF_VIRAL_TRANSCRIPTION | 57 | 20 | 17377 | 2626 |
CTDP1,TRIM8,POLR2I,POLR2G,POLR2L,POLR2K,TRIM11,POLR2D,SMARCA4,CHD1,POLR2A,GTF2F1,TFAP4,POLR2J,SP100,ZNF639,TARDBP,MDFIC,TRIM32,TRIM14 |
| 1.521e-04 | -8.79 | MORF_REV3L | MSigDB lists | MORF_REV3L | 57 | 20 | 17377 | 2626 |
ZNF500,NKRF,NFATC2IP,UBE4B,BRCA1,PDXDC1,FANCI,SSR1,TAF2,SEC23IP,CHD3,PIAS2,TBPL1,ATP6V0A2,ZBTB22,TAF5L,PPP5C,CPSF4,RNF14,IGBP1 |
| 1.522e-04 | -8.79 | TARS (threonyl-tRNA synthetase) | protein interactions | 6897 | 78 | 26 | 17029 | 2761 |
UGP2,HARS,VHL,CUL3,CUL1,BRCA1,EIF2AK4,MCM2,ISG15,UBLCP1,PAPOLA,HLA-B,FARSA,TPD52L2,AHNAK,RPS27A,HUWE1,CORO1C,DDA1,UBA5,NAA50,FUS,CDK2,NIPSNAP2,DVL2,NUDC |
| 1.522e-04 | -8.79 | USP19 (ubiquitin specific peptidase 19) | protein interactions | 10869 | 78 | 26 | 17029 | 2761 |
RPAP3,USP7,SNRNP200,HNRNPAB,BIRC3,XIAP,IRF3,SYVN1,PARK7,BIRC2,DERL1,HSPA4,SEC61A1,IARS,SIAH1,LAMTOR4,LRPPRC,SIAH2,SEL1L,SUCLG2,TNPO3,DMWD,CAMK2G,HDAC2,TMEM33,CDC37 |
| 1.524e-04 | -8.79 | TP53 Regulates Transcription of Cell Cycle Genes | REACTOME pathways | R-HSA-6791312 | 49 | 19 | 10287 | 1696 |
PLK3,BTG2,CCNB1,CNOT11,CNOT3,CNOT9,CCNA2,PCNA,RBL1,CENPJ,E2F4,TFDP1,E2F1,CDKN1B,CNOT6,CNOT6L,TFDP2,CDK2,CARM1 |
| 1.525e-04 | -8.79 | neutrophil activation | biological process | GO:0042119 | 493 | 105 | 17256 | 2622 |
RHOG,ADA2,RAB14,KMT2E,ADAM10,DYNLL1,RAC1,HEXB,NIT2,NHLRC3,GYG1,MAPK14,KCMF1,CMTM6,CPNE3,PA2G4,RAP1A,PSMD1,AP1M1,BRI3,TMBIM1,GM2A,KCNAB2,ENPP4,CPNE1,CCT2,TIMP2,NRAS,RAB7A,ARHGAP45,PPIE,CYSTM1,PSMB7,ATP6V0A1,RAB5B,TOLLIP,ALDH3B1,DSN1,AGPAT2,DDOST,SURF4,RAB24,PSMD3,CAB39,CANT1,ATP6V0C,ROCK1,PDXK,LTA4H,MAPK1,CAPN1,TUBB,SVIP,MIF,DNAJC5,GMFG,MANBA,PDAP1,LAMTOR3,B4GALT1,ASAH1,CDK13,MAN2B1,RAB6A,PSEN1,TMEM179B,GNS,CD59,PSMD2,CTSS,ARPC5,HUWE1,OSTF1,CNN2,MVP,LPCAT1,SPTAN1,CYFIP1,FTL,MLEC,RHOA,CREG1,C1orf35,HEBP2,PKM,ARMC8,CCT8,NEU1,HSPA1B,CAND1,XRCC5,CAT,RAB18,ATP6V1D,MAGT1,GOLGA7,SNAP29,SNAP23,ACLY,PGRMC1,IMPDH1,CTSA,PSAP,GPI,PGAM1 |
| 1.530e-04 | -8.78 | TOMM7 (translocase of outer mitochondrial membrane 7) | protein interactions | 54543 | 18 | 10 | 17029 | 2761 |
BAK1,SDHB,COX15,TOMM20,PEX5,FAM3C,ACAT1,SRSF3,TOMM40,TIMM50 |
| 1.530e-04 | -8.78 | Isy1 (ISY1 splicing factor homolog) | protein interactions | 57905 | 18 | 10 | 17029 | 2761 |
KEAP1,CDC40,XAB2,PPIE,LACTB,CRNKL1,DHX8,AQR,ZNF830,SDE2 |
| 1.535e-04 | -8.78 | cellular response to peptide | biological process | GO:1901653 | 313 | 72 | 17256 | 2622 |
MAX,WDTC1,ATP6V1B2,PRKACA,LYN,GNB2,APP,PRNP,EEF2K,CDK5,USF1,RAB8A,PDK2,ATP6V0B,CCNA2,MDM2,SHC1,ADCY9,PIK3R2,AKR1B1,AHCYL1,CDC5L,ADCY7,ATP6V1G1,KLF10,AKT2,GNG7,ATP6V0A1,CDC6,SOCS7,IDE,STAT1,ATP6V0C,MAPK1,C2CD5,ATP6V0E1,SLC25A33,AGTRAP,PSEN1,AP3S1,FOXO3,ARID1B,CFLAR,PTPN2,PTEN,ARHGEF2,ATP6V0A2,TIMELESS,CREB1,STAT3,ATP6V0D1,MYO5A,PDPK1,TGFB1,CYFIP1,DENND4C,PRKDC,PRKAR1B,RANGAP1,ADRB2,SRSF5,MEN1,PKM,PDE3B,APPL1,MAPK3,CACNB1,EPRS,ATP6V1D,CSK,ATP6V1C1,CPEB2 |
| 1.542e-04 | -8.78 | WANG_SMARCE1_TARGETS_DN | MSigDB lists | WANG_SMARCE1_TARGETS_DN | 347 | 78 | 17377 | 2626 |
SRM,GLT8D1,PNISR,CKLF,TAP1,SLC29A1,GLRX3,STAM,SLC25A37,FANCI,CDC42,UCHL5,POP7,NOC2L,AKR1B1,PDCD2,AP2B1,TAP2,TARDBP,RP2,MYBL1,PPIF,SHOC2,TRIM8,SEPT9,MIOS,LAP3,PBK,IDH3A,DRAP1,SLBP,GALNT7,PSMB9,GAR1,TXNL4A,HSPA4,HSPB11,GOLGA8A,PPA2,COX5A,DVL1,ZNF45,MRPL13,TMEM33,NDUFV2,HSPH1,PARP12,NSMCE4A,SRGN,MEF2A,ARGLU1,NCAPG,HDDC2,MAN1A1,SAC3D1,EBP,SMC3,FJX1,H2AFY,CITED2,NUDC,ETV3,MRS2,TBRG4,LY6E,NMT2,CAT,SDHB,HLA-B,SLCO4A1,PRDX3,WNT5B,DCK,TFDP1,MAPK6,SPCS3,EHD4,PDLIM5 |
| 1.548e-04 | -8.77 | RUVBL1 (RuvB like AAA ATPase 1) | protein interactions | 8607 | 230 | 59 | 17029 | 2761 |
LZTR1,EWSR1,H2AFZ,HJURP,SUMO2,RBM8A,PMS2,INO80E,UBE2I,ATP6V1B2,PCBP1,MEAF6,LMNA,SHC1,CDC42,HUWE1,UCHL5,PPME1,ZNHIT6,JAZF1,EFTUD2,PELO,AKAP8,SRI,ECD,FBL,PABPC1,PCBP2,FDFT1,CDC5L,RPAP3,SRSF11,TELO2,NTPCR,TK1,SNRNP200,PRKDC,CUL3,BRCA1,VDAC1,MATR3,CAND1,GNAS,HLA-B,TSC1,AHNAK,UPF1,KPNA1,HSPA4,HINT1,PDRG1,H2AFX,ACTB,RUVBL2,SMG9,YY1,SMNDC1,TUBB,DDX42 |
| 1.559e-04 | -8.77 | liver-carcinoma | COSMIC cancer mutations | liver-carcinoma | 15799 | 2399 | 17385 | 2587 |
HECA,ZBTB10,ABCC10,HEXB,TGOLN2,CCNL2,FBXO22,EEF2K,THAP4,RAD23B,ATP13A3,DNM2,ZNRD1,FTSJ3,USP34,CCDC57,ERCC1,NRAS,EHMT1,KIF15,HNRNPF,WDHD1,MIER2,DIDO1,RAB22A,SMAD2,MID1IP1,RPS27A,MYO18A,OGT,MPV17,COX5A,SMAD1,ZNF75A,ANXA11,SLC25A33,ZNF720,SEC61G,GGA1,MUM1,CCZ1,TRIO,CUTA,RAB23,KCTD17,HAUS4,EIF2AK4,APH1B,PARN,CDC73,MYL6B,ATG4A,TMEM179B,ERV3-1,PDXP,SMC3,C4orf3,GEMIN4,MVP,NUP85,PPP6R1,PABPC1,NSUN4,PPA1,IFRD1,AGGF1,FOXK1,RBM42,GTPBP4,MAP7D1,MRPL16,ELK1,EIF4H,RDH11,MAGED2,KPNA1,ETS2,TYW5,WIPI2,RUFY3,PDLIM5,ACSF2,RHOG,EXOC3,C5orf30,VTI1A,INO80E,SLC35B2,RCOR3,LCLAT1,CPNE3,KIAA1147,RBM23,ZNF420,AHCTF1,TBC1D22A,GMEB1,NSFL1C,SEPT11,ZNF226,GPD1L,ZC3H3,ARL5A,PDCL3,SNX8,ERMP1,EID1,IDH3A,POLR2D,MEF2D,TMEM147,GSTCD,TANC1,MAT2A,VPS26B,CORO1C,NSMCE2,CAMKMT,PPP5C,PITRM1,TUBB,COMMD10,ZNF445,HABP4,CCM2,FLOT1,BTN3A1,ATG2B,ABHD14B,PPP1R3B,GOLM1,ZBTB45,HUWE1,ZNF260,NAA50,ANXA5,LTN1,UBE3B,NAP1L4,ZNF710,ST8SIA2,RPL22L1,SPTAN1,STAU1,DDX24,TCTEX1D2,TACC1,MRS2,HEBP2,LLPH,RAB3IP,TTC33,PICALM,SH3BP5,SLC19A1,ACOX1,FAM3C,AEN,PARP10,YWHAH,THAP5,GPATCH4,FAM129A,TRIM11,YTHDC2,SNX15,RBM8A,NENF,SND1,RUFY1,TRIM65,ZER1,PRNP,KRR1,RAB8A,NUP210,NT5DC1,NOC2L,EIF5,TACC3,VPS13B,RYBP,PTPN18,MIOS,MBLAC2,SNRPB,CDC6,UTP3,PBRM1,ODC1,USP21,TRAM2,FBXO28,BCL7C,ARRDC1,ADAM9,DVL1,NUMB,ZNF564,CTU2,PARP12,ZCCHC9,CENPF,LAMTOR3,CHCHD2,NCKAP1,LYRM2,RSAD1,TNS3,SUB1,RINL,SSBP3,KIF13B,MBD2,XPA,AHCY,RBM3,GLE1,MRPL48,LRSAM1,HDHD2,NTPCR,NSDHL,AMD1,CAMSAP1,ZNF761,METTL22,ICAM2,STYXL1,APPL1,BBS12,RXRB,SDHB,PCM1,GALNT2,TMEM168,NLRC5,MYO9A,BTBD10,CCNB2,USP7,GLT8D1,RPLP2,SUCLG1,ARID2,TMX4,SLC2A1,ATP6V1B2,LYN,VAV1,TMEM69,MRPL50,PSMA6,ZNF473,ZNF302,BRPF3,TARDBP,BCAP29,CTDSP2,PRPF19,PPIF,KDM3B,MND1,CLCN3,BIRC3,RAB7A,ANKRD33B,PPIE,CHMP2B,VDAC1,EIF3H,TMEM201,GLOD4,IDE,DHX16,UHRF2,CHMP4B,XRCC3,PARD3,BCL2L12,C19orf53,KLHL21,PDAP1,TMX3,CDCA8,GTF3A,ARF1,SLC12A9,TUBGCP2,DNAJB9,HOMER1,WBP1L,POLR1B,RNF5,RBM15B,PPAN,RHOA,RPRD1A,BTAF1,TOP3A,ARHGEF12,PCGF1,DDX23,RAB18,CACNB1,TRIM26,PDCD6,ATP6V1D,L3MBTL3,NEIL3,CTBS,BBX,IMPDH1,TAF12,NR2F2,PGAM1,HIPK3,IFI16,TXN,NUP188,H2AFZ,PNISR,TMEM203,PRKCSH,USP39,UBE2I,SLC25A37,ZNF428,RAB4A,TRA2B,SUCLG2,CISD2,ZNF800,CDC5L,SGCE,OSBP2,NSUN2,USP22,CLNS1A,EIF3A,ZMYM3,DOT1L,IWS1,ANKRD10,WAS,KIF18B,TPP2,C1orf109,ZMAT3,B4GALT2,PRPF38B,RECQL,C9orf78,EWSR1,GADD45G,RRM1,ACAP1,B4GALT1,SUPT7L,TMEM165,NPLOC4,CNOT3,WDR48,SPAG5,RTKN,CEP104,EXOSC7,KLHL5,LRRC8D,MSH2,PIGG,FBXL7,OSTF1,MRPL40,TNRC18,SYTL3,FAM171A1,APOL1,EIF5A,GCC2,PRIM2,ELL2,RDH10,MFNG,RPS24,GORASP2,CAPZA2,ADRB2,CCT8,MTR,PHF6,PFDN5,SLCO4A1,TTC13,GOLGA2,RBMX,MED15,PIAS2,APPL2,SAMD8,CDKN2A,NUDT3,ZNF511,ATXN3,RAF1,KIAA0232,C2orf49,CD320,EPM2A,CCNA2,MTMR4,BRI3,TP53BP2,AQR,RBM12B,ILKAP,CDK12,SAP30,BRD4,DRAP1,NARF,LRRC8A,ELP4,ABHD11,PKMYT1,ASB13,SERP1,TRIM28,SUPT16H,EIF3K,CHMP4A,CBWD1,ATF6,XRCC4,PRPF4B,ADAM23,NDUFS1,DEPDC1,MECP2,SECISBP2,HMG20A,WWP2,SLC25A36,JAKMIP1,CCNK,DNAJC8,AXIN2,CITED2,JMJD4,ANKRD37,KAT2A,TMEM126B,RABIF,ADSL,PACS1,BMS1,KCNQ1,OTUD3,ARSK,MACF1,KIF11,COMMD4,KLF6,SMAP2,FADD,SH3GLB1,MYO1F,CBX3,TMEM127,DUSP11,DDX5,WDR62,TAF6,ESPL1,DDB1,DEF6,FAM83G,IPO4,UBL3,NAT9,LYRM4,GPR132,UBE2Q1,PTP4A3,BRIX1,MRPL19,ZNF696,SF3B2,PCYOX1L,SYNM,GOT2,JAZF1,HADHB,RPF2,SLC35C2,CNNM3,CARM1,SRPK2,WDR41,LARS,ZCCHC10,CCDC138,LRBA,TMEM216,SUMF2,KMT2C,OGFR,PRPSAP1,ASF1B,RPL37,MAN2A2,EIF4ENIF1,NIP7,U2SURP,MIA2,ZNF268,VPS4A,ATP6V0E1,PPP1R2,PM20D2,XPNPEP3,RGS2,LYAR,POLR2I,TRAFD1,SUGP2,GBA,EIF2A,SYVN1,DAPK3,ARHGAP15,MASTL,UAP1,FN3KRP,YWHAZ,CTSA,TMEM14A,TOB1,TSEN15,ADNP2,TCF12,PRKAB1,MDH2,SMARCA4,ORC1,RRN3,UBXN2A,IARS,CD3EAP,KIF14,EXOSC1,CS,CLTB,DNAL4,CSTF1,POU2AF1,UBQLN4,PGGT1B,SELPLG,SMU1,ATXN1,GLO1,OGDH,BICD2,CADM1,EDEM2,HERPUD2,TOLLIP,FANCE,MBD3,PDHX,RPS9,ALKBH6,SURF4,DUS3L,ARNTL,ANP32E,FKBP5,TMEM101,CCDC125,ABCA1,PDCD2L,GCLM,RAE1,DCTN2,NUP54,CHIC2,PAWR,MXD4,DCUN1D4,PIP4K2A,XPR1,FERMT3,KIF5B,KLHL20,SEC24C,RRBP1,ARHGEF2,ANP32A,LDLRAD3,C12orf75,STAT3,MYO5A,NIPAL3,TXNL1,PHF20L1,DCAF6,FAM49B,TMEM39A,ATP2C1,RFFL,COG1,RCOR1,PRMT2,TFEB,LEMD2,UPF1,ELMO1,ZC3H7B,DTX4,ZMIZ1,HRAS,CCDC93,TMED7,PIGQ,AGPAT1,CNTROB,PPP1R16B,GSDMB,TTC9C,PDS5B,NUP153,PGAP2,TMEM115,PLEKHM3,DCUN1D5,BRMS1,PWWP2B,TRIM47,WDR11,AXIN1,SMG9,TRIM52,LONP2,NDUFV2,PHF23,CERK,SLC4A2,EZH1,ITGB5,LMNA,DDX56,EIF2S2,SLC38A5,FOXN2,CARS2,PRRC2A,C16orf72,RB1CC1,ZMYND11,PGS1,MYBL2,UHRF1BP1,MPG,MATR3,CYB5A,NCDN,POLR2J,SETD3,TEX30,PTAR1,CNOT6,NDE1,EGLN1,ZNF207,ANKRD27,PPP1R37,ABCA3,SARNP,IVNS1ABP,MON1B,RMI2,TMEM97,NIT2,NUF2,ZNF267,TCF19,TMEM161B,APP,PRKD3,CLUAP1,ATP2A2,UTP18,GRSF1,DUT,ZCCHC2,ANAPC7,RNF19A,FAM76B,CLN6,TMEM9,GCC1,RNF169,ADCY7,ATP6V1G1,ENPP4,RNPS1,CDCA2,FKBP3,GPR137,DDX17,CHCHD3,PEX5,CDC16,HIPK2,MBOAT1,TICAM1,PDXK,ZBTB11,ANXA6,TMBIM4,GMCL1,UBE4A,ETS1,WRB,ZNF92,PNO1,CAPN2,ADD3,SUV39H2,TTLL12,TPCN1,TMX1,LYPLA2,HNRNPM,MFSD12,LDHB,PPP3CA,NUDT8,POLK,JTB,EMP3,MTMR12,ZP3,PDE3B,KIF18A,CCDC6,MAPK6,LY75,SLC25A19,RGL1,PSAP,WDR76,IGBP1,FAF1,SNAPIN,COX15,AGRN,THOC1,GNPDA1,GPBP1L1,PPP1R15B,CSNK2A1,GIT2,BIRC2,ATPAF1,DLG5,ABL2,XRCC2,ZFYVE27,MCMBP,PTPRK,CDC37,METTL1,HARS,GMFB,ESYT1,ANLN,RAB5B,RHEB,DPYSL3,TBC1D17,CDCA4,TONSL,NRM,NAGLU,ACTB,ZNF45,TMUB1,CTCF,ASAH1,DOCK11,CRLF3,ASXL2,LRRC14,NUS1,SLC27A4,MDFIC,MAML1,CYTH1,NQO2,UTP15,EIF2AK1,EIF4G2,ZDHHC3,ITPRIPL1,CDC27,SNAP23,TBPL1,PRMT7,KCTD7,NDUFA5,CYLD,UGP2,DYNLL1,COPE,ZADH2,GGPS1,RPAIN,RAD23A,ATP6V0B,PDK2,STRBP,DUS4L,PDCD2,SAP30L,SLC39A9,CLPTM1,RPL29,RPL35,BTG2,DNAJC9,MTMR6,NFATC2,KDM1B,ARL5B,USP36,CCDC127,MRPL2,ATP1A1,CLK3,PSMD3,MAFK,CEP55,NDUFA11,DNAJC17,ZNF436,NCOA1,SLC25A39,ZC3HC1,ATXN7L2,CDC40,GOLIM4,SMAP1,RRP15,DAP,GNE,SMC6,ARFIP2,CHAC2,BZW2,WRNIP1,TMA7,CENPM,PTGES3,CAMK2G,MLEC,ZNF202,PPWD1,FAM50B,RHOT2,NEU1,TPD52L2,GOLGA7,TWSG1,PGRMC1,GLG1,FAM126A,RPS6KC1,UBE2C,PPCS,NDUFB6,TMEM41B,ZDHHC8,PLXNA1,CCNB1,SLC20A1,COMMD6,ABHD14A,POLR3K,ASAP2,SNUPN,CNPY4,PLCL2,SEH1L,ATG9A,PBK,MKI67,DDX20,AMDHD2,SLC17A5,GALNT7,CCNF,FOXRED1,RBM47,PTER,WDR4,DHTKD1,TRAF5,HDAC2,PWWP2A,HSPH1,LIME1,MAPRE1,CHTF18,ADO,KIF23,SLC35B1,NOTCH2,PMF1,JMY,FKBP1A,NDUFAF6,SLC31A1,SNX18,CTPS1,ATP6V0A2,PIKFYVE,RNF135,LPCAT1,EEF1D,TMED2,PHF10,FTL,DDX28,ZNF84,SIGMAR1,PIP4K2C,FAM133B,RIT1,PLEC,KDM3A,SF3A2,FAS,EPRS,ZNF777,TMEM54,QARS,TCOF1,CABLES1,NRBP1,DNMT3A,RWDD1,CKLF,TRIP10,SF3B1,CAST,SUZ12,RPS6KA1,RAC1,GPR89A,OLA1,SNN,GNB2,FLAD1,APLP2,KDM2A,TNPO2,CDKN1B,TALDO1,GPX4,ATP13A1,RFC3,MAPRE2,ERF,CUL3,SLBP,KIAA1586,H2AFV,GAR1,PSMB9,POLG2,DHX57,NSA2,HSPA4,MRPL55,JAK1,TBL3,SEL1L,KLHDC4,B4GALT3,PDCD11,ATMIN,POLQ,POU3F2,OTUD5,NCOR2,PKP4,SCAMP3,BABAM1,CDCA3,SLC25A12,BLM,TMCC3,GTF2F1,CRAT,AHSA1,PRC1,UPF2,COPS7B,SLC38A10,CNPY3,UBE2M,IFT46,TMEM160,TSHZ1,ZFP64,STRIP1,DENND4C,DENND1B,WDR18,ILF3,LRRC1,RHOT1,TSR2,MARK2,ECH1,PRDX1,PLD3,NUCB1,GNA12,FBXO21,C1orf131,PRDX3,PFDN4,HNRNPH3,TFDP1,STX18,KHSRP,ASNA1,CPEB2,SSSCA1,BYSL,VPS29,S100PBP,MIB2,IER2,PTMS,NOP2,UBN1,NF1,DCAF15,FLYWCH2,ALKBH5,MOGS,UBE2Z,TAF6L,MAPK14,BECN1,SNAPC4,RNF103,BCAT2,MBD4,METTL14,IMPAD1,ZNHIT6,RCSD1,PHTF1,SRI,KIF22,ZBTB22,NFU1,TRIM14,ELOF1,COPS8,FYTTD1,TRIM8,RRM2,ABHD5,CXXC4,UBTF,PAF1,UEVLD,PQBP1,IARS2,ATXN2L,GALNT10,STARD3NL,RPS15,PIGN,AGTRAP,CIB1,XPO7,SRRT,ZNF449,CAPZA1,GLTP,BCL2,KIFAP3,N4BP2,HP1BP3,VOPP1,THNSL1,CAND1,C22orf46,GNAS,TSC1,RBM25,CDCA5,ZFP90,NANP,RBBP4,ZBTB24,SMARCD1,MBD1,WASF2,MMACHC,TOMM20,IFI27L1,GNPNAT1,MPHOSPH8,HNRNPUL2,CHD1,MEAF6,C2orf68,CCDC50,AKAP8,PARL,RPN2,CHTOP,FAM3A,F2R,TMEM14C,ABI1,HTRA2,MOSPD1,RLIM,FAM172A,ZNF500,PSMB7,NLN,WIPF1,BUD13,NDUFB1,PEF1,EIF3G,BTBD1,TAB2,CHCHD1,TULP3,WDR59,CANT1,SCARB1,GAS2,USP11,SMURF1,TSPAN5,CDS2,MRPL42,EYA1,CDK2AP2,MRPS26,LETMD1,KLF13,HDDC2,RGS1,MAN1A1,FBXO5,GART,TANK,BRD7,MRPL11,SAMD4B,ZDHHC18,GTF3C6,POLR3GL,MEN1,ZNF407,MFN2,COX8A,ZRANB2,MBD6,SRSF3,ATP6V1C1,IDH3B,TATDN1,TSC2,LACTB2,CMTM6,RBM4,ANKRD39,RPL23A,CDKN2C,NAPG,USF1,DNAAF2,MECR,AP1M1,UPRT,CRY2,ECD,MOB1A,TIPARP,LRRC59,RHBDD2,MGAT5,BAK1,ZNF559,RHOBTB3,GABPA,WBP1,NUTF2,ARF4,GINS4,KRIT1,BOLA3,AHNAK,RAD18,PDRG1,RNASEL,CHPF2,PDCD4,SMNDC1,NXT2,HIVEP3,KIAA0100,CLSPN,RHOC,DHX9,PDCD7,PSMD9,HAUS2,COPB2,CD59,TFAP4,RNFT1,RIMS3,MEGF8,FBXO7,EFTUD2,CPSF4,MRPL21,LUC7L2,EIF3L,MTA2,TYW1,USP10,ITM2A,SSR2,MTX1,SFXN5,FNTA,PDLIM1,TXNDC16,ZNF830,TMEM159,MRPL3,ALS2,FAM72A,TRIM41,KARS,NQO1,POC1A,ANK3,PTTG1,TPX2,TBC1D13,DAZAP2,GLRX3,STMN1,REPS1,ABHD16A,FBXL6,SH3BP1,MTA1,UBA5,CLCN6,INTS12,RPRD1B,CGGBP1,CPNE1,SEC61B,POLR2L,FAM118B,GOPC,E2F3,CIRBP,RPL38,CRNKL1,PFKFB3,GORAB,RAB1A,GIGYF1,TMEM184C,PPP2CA,KIF2A,CCDC14,LSM6,RNF38,SNRPG,DMWD,USP13,MZT1,ZFP91,TRMT6,IP6K2,WDR5,SLC25A43,IFT27,PMVK,NEIL2,RRP36,SRXN1,RPA2,PSMD2,CLIC4,PDCD10,CBWD2,COQ4,ITGB8,ARHGEF1,GTF2H2,TTPAL,UTP20,MAGT1,GPS2,DBI,CD81,TMEM131,WDR13,FANCI,PAPOLA,CREM,FANCL,TET3,GLIS2,IL6ST,INTS1,SLC44A1,MTPN,ASB6,PLK1,SEPT9,CELSR2,RBX1,APH1A,RAD51AP1,ZBED5,CKAP2L,PSMG1,EAF2,IL12RB1,KRTCAP2,LUC7L,LSG1,C1orf122,ALG3,TRIM4,AGPAT2,CHD3,ZNF367,E2F4,PRPF4,KPNA2,BEND6,CLN3,DNAJC30,FAM208A,NGLY1,POT1,MYL12B,CCDC137,RMND5A,HJURP,DNAJB2,FAM53C,NKD2,SDC2,CDK13,ADCK5,COX4I1,DNAJB1,RAB6A,ARID1B,C1GALT1,MLX,UBE2Q2,CCP110,ZNF746,ARL6IP1,CTR9,NIPSNAP1,ABHD2,DCAF8,ACSL3,LDB1,MAP4K3,ARMC8,RBM38,NMT2,IRF5,HAUS8,MBIP,ORMDL2,COX7A2L,SIL1,DTD1,UNC13C,BCCIP,SART1,TRAF7,NDUFAF2,TOR1AIP1,ZNF416,ZFYVE21,TM9SF3,RRAGC,OIP5,NRF1,WDR44,PPME1,EFCAB11,RPAP1,CABLES2,LMAN1,AHCYL1,TOP1MT,STRAP,SPSB3,ZNF583,SNX25,ARHGAP17,POLR2G,ZNF780B,PPT1,NUP155,DCLRE1C,MRPS14,RHBDF2,SUGP1,RBL1,FASTK,UBXN2B,STK38,AP1S1,SLC22A23,H3F3A,CHID1,SMAD4,SLC30A9,CMAS,UNK,NADSYN1,HMGN3,NCAPG,SCYL2,FZD6,HERC3,GTPBP3,CTSS,ORC3,RNLS,YTHDC1,ACP2,HMGN5,CSRP1,METTL5,ABCF2,TUFM,RANGAP1,PNPLA8,HAGH,API5,ZFR,SEC23IP,E2F1,TMEM219,USP20,RBPJ,PDCD6IP,MAX,GXYLT1,LUZP1,ADAM10,CXXC1,TSC22D3,AP3M2,CUL1,GYG1,NANS,OAT,MYEF2,ANKRD26,PA2G4,NOL11,FIZ1,ZNF200,MARCH2,SLC26A2,SRSF10,SRP72,KLF10,LACTB,RFC2,RAB2B,PRIM1,MAP3K4,HHEX,LUC7L3,MAP4,MRPL27,BTF3,PTPDC1,NMD3,CCDC59,PTOV1,COX5B,DNAJC5,SCOC,DHPS,POLR2K,ANKH,PRKAA1,C16orf87,VAV2,GSPT2,TATDN3,DLGAP4,PXMP2,PRPF39,PSEN1,ZNF79,PDXDC1,VPS25,NDUFS7,YY1AP1,C12orf10,FAM192A,RPN1,LHX8,ARPC5,ZNRF2,TPST1,DAPK1,PIK3IP1,CYC1,SOCS5,FDFT1,PIGT,EMB,WDR1,ZNF574,C1orf35,EXOSC9,ARID1A,PTTG1IP,C9orf40,FXR1,GOSR1,MAP2K2,TWISTNB,AKAP1,XRCC5,HMGN2,PI4K2A,CAT,DERL1,MTHFD2,HSPBP1,ARAP1,USP32,FAM83D,CABIN1,SMPD4,GPI,CYTIP,TP53RK,REPS2,RAB11B,UROD,POMP,BCL2L1,NUDT19,DECR1,RALB,ADCY9,LPIN2,MRPS27,SOCS6,TTC3,RNASEH2A,CFL1,ANKLE2,CDC123,OAF,VDAC2,EDF1,EML4,ERC1,ANKZF1,ZNF282,DSN1,DDOST,HINT1,DGCR8,SAFB,HAGHL,FTSJ1,RWDD4,LMBR1,NCLN,BEND3,EYA2,DYNC1LI2,MANBA,B4GALT5,SLC41A1,FAM76A,TKT,CBLL1,ARGLU1,LANCL1,POFUT1,FAM8A1,HEATR5B,HLA-A,EBP,RFWD3,NDUFA2,FJX1,FUT8,BTF3L4,PTPN11,MRPL54,FEM1B,RPL19,CNN2,NDUFA3,MTX2,MSH6,PDLIM2,LONRF3,RFXANK,FBXO9,GUF1,RPL32,ZHX1,NDUFS5,WDR91,POLA2,ZNF76,MTX3,COPA,UQCR10,PHRF1,HMGXB3,ABCB10,COMMD5,MAP1LC3B,DST,RAB35,SIVA1,GPATCH1,DRAM2,DEAF1,TRAPPC13,SNRNP200,LAP3,NCK1,VHL,ARHGDIB,PITPNB,HSPB11,BRWD1,PPM1G,SH3GLB2,CRCP,BAZ1B,ACBD4,STK11,CLU,CHEK2,ZSWIM3,TSTD2,CHPT1,MRPL13,DCAF5,CAPN1,UBE2D3,NSMCE4A,PPP1R12A,ZCCHC8,GORASP1,UBXN1,NACA,C19orf25,RPL15,PCSK7,EPN1,THRAP3,QSOX2,TTF1,PRPF18,NUP205,CHKA,DTL,MED10,ZRANB1,SLC12A2,ATP6V0D1,CSNK1G3,CREG1,NUDT4,RPL6,VKORC1,SLTM,EVC2,KLHL15,SIAH2,SLC16A1,EHD4,SNRNP70,APOL2,N4BP2L2,CHMP2A,CORO7,FEZ2,PMS2,UCK2,UCK1,CLCC1,EXT2,MXD1,USP5,HNRNPA2B1,SAP130,NVL,PPP6C,CYB5R1,ZNF770,EBAG9,RNF25,PCGF6,METTL2A,PON2,HNRNPR,HPS5,STAT6,MAPK1,BRD9,TMEM33,DNAJC2,TRIP12,SHPRH,SCYL1,VPS45,MYO9B,GFM2,SPPL2A,FASTKD3,MZT2A,PPIG,ZDHHC13,TMEM99,H2AFY,NDUFS8,ATG13,ERI3,FBL,SLC35A1,FRMD8,MICAL3,TGFB1,ELOVL5,HEMK1,TIMMDC1,HELB,PSPC1,MIER1,SCFD2,NDRG3,ARL17A,CDK11A,MEGF9,ACAT1,CENPT,PLOD3,RAB3IL1,ZSWIM6,RAB14,ADD1,KDM4A,MRPS15,XIAP,DHX8,GLUD1,ANKRD23,PABPC4,CDK5,CALM2,PSMD1,NEK6,NSRP1,RABGAP1L,SRSF4,FNIP2,KCNAB2,PCBP2,MLST8,PLK3,ZNF672,HSDL1,MRPL43,PPFIA3,SMC2,ICMT,SLC50A1,STOML2,LIMK1,ZNF689,PRDX5,ATE1,MLYCD,ST3GAL2,ATP6V0C,FBXL3,E2F2,PFKP,AAAS,DDX42,SSRP1,MRPL9,MRPS2,STRN4,TOP2B,ZNRF3,TMED3,DDRGK1,RAVER2,GNS,INTS7,INPP5A,MCM5,PHF14,ZNF326,UBE2QL1,NAGPA,TIMM8B,TSPYL4,TSPAN31,DHX29,TEX10,MAN1B1,RPS10,CBFA2T2,ABCF1,LRRC14B,DTWD1,PTPRF,SCARB2,OSBPL11,CCDC86,DUSP3,SLAIN1,MDH1,HEXA,RNF139,SNX14,ZNF296,TRERF1,UBR2,CHD1L,ACTR3,WDTC1,MYH9,CREBL2,NIPA2,PRKACA,SAFB2,ANKIB1,STAM,ARL6IP6,RAB21,SP100,ZKSCAN1,DDA1,NUP107,ANKRD13C,MAVS,CEP63,ATF2,DCTN1,SHOC2,MAP4K4,WBP2,ATP6V0A1,NUSAP1,NDUFA7,DNAJA1,TAF2,C19orf54,SEC61A1,RPLP1,WDR7,CBLN2,FUS,LRP8,COIL,LRCH1,GALK1,ZNF786,RPS2,SESTD1,TRAK1,SIKE1,AKT1S1,KRI1,FBXO3,ERH,GATC,NDUFB4,PPP1R8,PRDM4,GTSE1,GEMIN6,DCP1A,SGCB,S100A6,IMPA2,NUDC,PDPK1,TK1,GUK1,TNFAIP3,GALC,ZNF512,KIAA0930,MRPS10,DDX39A,RPA1,ZNF180,ZNF862,KEAP1,POLE,TATDN2,PITX1,CAPN7,LRPPRC,PML,HMGB2,USF2,ANAPC4,SRM,DDX47,MCCC1,CDC42SE2,S1PR2,CDIPT,SEC16A,SSR1,LIN9,PCNA,ZNF639,TRMU,ETV6,PIK3R2,TXLNA,PPCDC,FAM86C1,MYBL1,CCAR1,MRPL32,ABCC5,BAZ2A,PBXIP1,TLK1,MRPL12,EZR,LNX2,LRP5,BRCA1,PRKRA,STX16,EPB41,OPTN,SEPT1,SOCS4,QRSL1,PIEZO1,OSGEPL1,GLCCI1,NUDT11,NAA60,SEPHS2,LZTR1,RACGAP1,PPP3CB,B4GALT4,RLF,RAPGEF6,SNRNP25,RB1,VASP,MED8,VMP1,PPIL2,TIMELESS,AHDC1,ALDH18A1,TMEM8A,PREB,ABCC1,TRAPPC9,AACS,MEMO1,KRAS,RTF1,UBE4B,NFATC2IP,LY6E,ARPC1A,ZNF174,PSMC4,GOLGA4,SYNCRIP,PALB2,PRPS2,NIPA1,TIGD2,RNF114,FOXM1,MRPL39,XAB2,SUMO2,DUSP22,COMMD8,RPL11,CSDE1,MDM2,CORO1A,METTL9,MINPP1,POC5,DVL2,GM2A,PSMA8,COQ10B,CPOX,TIGD5,SLC26A6,CYP20A1,PRPF3,TXNL4A,RPSA,SRSF1,DNAJC10,ZNF700,SCAP,PLEKHG4B,TIMM17A,FAU,LTA4H,AP2S1,USP53,INTS2,CTDP1,MIF4GD,CDT1,ARID5A,SUMF1,GGA2,AP3S1,CSNK1A1,RMI1,TFRC,PTPN2,STARD9,GSTK1,NDUFV1,SLC1A4,CWC27,SLC35B4,DDX31,ABCD1,RPAP3,CNTN5,SNX2,ZMYM5,CHCHD6,BSDC1,KPNA4,CDKN2AIPNL,TFE3,SNAP29,CDCA7L,PKD2,ACADM,CHMP7,SAT2,GCSH,ZNF496,TAP1,YTHDF3,NHLRC3,IKBIP,EIF1B,ELMOD2,KIFC1,DBNDD1,CYB5RL,PARPBP,CDC25B,PRADC1,DNMT1,NOL12,ORAI2,AKT2,NOL8,GNG7,AURKB,MCFD2,SLC25A5,ZFAND5,MAK16,STT3A,TMED10,PSMD8,EIF2D,ITGB1,PTPN7,UQCRH,ARRB2,RTN3,ZNF598,SVIP,DDX58,WSB2,PPIB,MUT,GMFG,HLA-E,NDUFA4,MAN2B1,METTL3,CFLAR,NDUFS4,RNF121,MEX3C,KLF16,HDAC7,DAD1,BDH1,PCYT2,GNAI2,ANKHD1,MORC3,TERF2,KCTD20,SEPT8,DCTD,PKM,TOMM40,PATL1,ADSS,SERTAD2,SERF2,ZFP92,NSF,DCK,ERGIC3,ACLY,LPCAT4,VCPIP1,YY1,PPP6R3,MAP3K5,PPP6R2,RNF14,CDK2,ZC3HAV1,SYS1,ZBTB37,URB2,EIF3D,MAGED1,KLHL18,ADPGK,SLC25A44,AP1B1,SDHA,PAIP2,PHC2,CRKL,TERF2IP,MOAP1,CYHR1,ZNF75D,SHC1,UCHL5,NAA35,CCT2,CDKN2AIP,MKLN1,LYRM1,GALK2,CDC23,SHCBP1,AP4E1,PRDM11,VEZF1,PPP2R5A,ACYP1,STAT1,PPA2,TRIM32,RHEBL1,R3HCC1L,C1orf112,TCF3,MRI1,BRAP,AGPAT3,MYNN,SDF2L1,SPR,RAB11A,REEP5,FOXO3,MAD2L2,CCDC28A,RBM17,MAT2B,PTEN,CENPJ,TAGLN2,OSTC,PACS2,NCOA2,SMC4,NEK7,NET1,PARP4,TBRG4,ANAPC2,RPL27A,YIF1A,SGSH,HGS,TTLL4,SLC38A7,MFAP1,CCDC69,BRWD3,ESYT2,SKA3,NPHP4,UBE2E2,HNRNPAB,PLXNC1,TMEM184B,ST13,DNAJC24,ZNF107,SLC29A1,KIF2C,AGFG1,SIRT2,FKBP2,USP48,SNRPD3,UBQLN2,CUTC,EDC3,UBLCP1,ZNF804A,RAP1A,THADA,EIF4A3,AP3S2,ATG3,DPYSL2,PPP1R12C,AKR1B1,NDUFB9,JOSD1,RP2,TTC4,TECR,ARID4A,FGFR1OP2,TIMM50,TDP1,DPM1,FOPNL,SLC16A7,WDR82,STK17B,DHX15,CHAF1A,GEMIN5,COPS6,SASS6,RPS26,PSMC1,SLC12A7,TBC1D12,TM9SF4,ZNF768,UFC1,MED13L,TIA1,MEF2A,EPHX2,PITHD1,RHBDD1,NFATC3,BANF1,ZNF335,BUD31,YBX1,KNTC1,ACAD8,UBE3C,ZNF189,ALDH9A1,KDELR1,TSTA3,CIC,OXR1,SEPT7,NAP1L1,ODF2,EXOC4,KIAA1328,PITPNA,NAA20,PTDSS1,MZT2B,PDSS2,C7orf26,TMEM106C,IMMT,ASH1L,CHERP,WDYHV1,PLAGL2,CHKB,IRF3,TWF2,PAIP1,ANKLE1,FARSA,SAR1A,SCAMP4,APOOL,PDIA6,ACSL5,TOR1AIP2,AZI2,RAD54B,TMEM41A,DAP3,ZNF317,GADD45B,AKNA,REEP4,CBX4,MIF,KIF3B,GOLPH3L,SH2D3A,CASP6,TOR3A,SRGN,DBF4,MFSD10,CTNNBL1,CLDND1,TTC17,SLC25A1,GINS1,CSNK1G2,TELO2,ADAM17,HMGN1,NASP,ASPM,PPP1R21,PRKAR1B,SYMPK,TARS,SNRPA,HLA-B,ATAD2,PLAA,ZNF330,OSBPL8,KBTBD7,PREPL |
| 1.568e-04 | -8.76 | oligosaccharyl transferase activity | molecular function | GO:0004576 | 10 | 7 | 17224 | 2647 |
RPN1,RPN2,OSTC,DDOST,MAGT1,STT3A,DAD1 |
| 1.576e-04 | -8.76 | tRNA-containing ribonucleoprotein complex export from nucleus | biological process | GO:0071431 | 33 | 14 | 17256 | 2622 |
NDC1,NUP188,NUP210,RAE1,NUP107,NUP54,NUP62,NUP153,NUP155,NUP85,NUP58,AAAS,SEH1L,NUP205 |
| 1.576e-04 | -8.76 | tRNA export from nucleus | biological process | GO:0006409 | 33 | 14 | 17256 | 2622 |
NDC1,NUP188,NUP210,RAE1,NUP107,NUP54,NUP62,NUP153,NUP155,NUP85,NUP58,AAAS,SEH1L,NUP205 |
| 1.579e-04 | -8.75 | BILANGES_RAPAMYCIN_SENSITIVE_VIA_TSC1_AND_TSC2 | MSigDB lists | BILANGES_RAPAMYCIN_SENSITIVE_VIA_TSC1_AND_TSC2 | 70 | 23 | 17377 | 2626 |
CCT2,PPIB,ZNF496,TOMM20,OLA1,GYG1,FXR1,VDAC1,SLC25A5,RPL36,EIF3K,NSA2,NAP1L1,HSPB11,PRDX3,PPM1G,CS,AHCY,BTF3,IGBP1,RPS26,TUBB,KDELR1 |
| 1.587e-04 | -8.75 | GTGTTGA,MIR-505 | MSigDB lists | GTGTTGA,MIR-505 | 97 | 29 | 17377 | 2626 |
PDPK1,UBE2D3,OTUD5,ZMYND11,MECP2,YTHDF3,B4GALT1,KRAS,RTF1,BICD2,CYFIP2,MAPK14,H2AFV,DHX15,EIF3A,SRSF1,AKAP1,DPYSL3,HUWE1,ARNTL,USP32,FAM122A,CREB1,CITED2,SLC12A2,GCC1,ALS2,CGGBP1,LRCH1 |
| 1.587e-04 | -8.75 | response to mitochondrial depolarisation | biological process | GO:0098780 | 19 | 10 | 17256 | 2622 |
ATP5IF1,GPS2,GBA,ATG13,BECN1,SMURF1,HTRA2,OPTN,MFN2,CDC37 |
| 1.589e-04 | -8.75 | CTNNB1 (catenin beta 1) | protein interactions | 1499 | 350 | 83 | 17029 | 2761 |
USP7,RPLP2,FOXM1,TRIP10,CUL1,CSNK2A1,SMARCA4,DAZAP2,APP,HNRNPA2B1,DLG5,CCNA2,SIAH1,GLIS2,PIN1,ATF2,DVL2,CARM1,PTPRK,PLK1,COPS8,WBP2,CUL3,EZR,BRCA1,ERBIN,MCM2,FANCE,RPSA,GEMIN5,SMAD2,HINT1,AXIN1,UHRF2,ACTB,FUS,BTF3,DVL1,SMURF1,SMAD4,CSNK1D,PARD3,UNK,MAPRE1,PHB2,TCF3,DHX9,CSNK1A1,PSEN1,FOXO3,CDC73,LMNA,PTEN,HUWE1,HDAC7,AXIN2,PTPN11,CREB1,NCOA2,HNRNPM,LDHB,IFRD1,KAT2A,RB1CC1,PKM,MEN1,ARMC8,ISG15,HSPA1B,FAS,PTPRF,CDC27,RBMX,PML,YWHAZ,DDX5,RUVBL2,ZMIZ1,RNF14,CDK2,TOB1,FAF1,DDB1 |
| 1.591e-04 | -8.75 | IKEDA_MIR30_TARGETS_UP | MSigDB lists | IKEDA_MIR30_TARGETS_UP | 111 | 32 | 17377 | 2626 |
PPP1R12A,B4GALT5,CAST,MAP4K4,TAOK1,KRAS,GALNT7,AP3S1,BECN1,KDM3A,PIP4K2A,ARF4,XPR1,PAPOLA,PTPN2,GOLGA4,PDCD10,WDR44,LRRC8D,ELMO1,DPYSL2,CSNK1G1,TFDP1,WDR7,SOCS6,BCL2,CNOT6,YWHAZ,MAML1,CPEB2,ARID4A,USP34 |
| 1.591e-04 | -8.75 | FAM19A3 (family with sequence similarity 19 member A3, C-C motif chemokine like) | protein interactions | 284467 | 74 | 25 | 17029 | 2761 |
JMJD4,CTU2,SNX27,TRAPPC9,NDUFS1,DHPS,VHL,MANBA,PBK,THNSL1,KDM1B,MAPK14,GGPS1,BIRC2,CSDE1,PPP2CA,FLAD1,IDE,DPYSL2,FAAP100,PRMT7,AHCYL1,MCMBP,PPP2R2D,ZC3HC1 |
| 1.593e-04 | -8.74 | PCM1 (pericentriolar material 1) | protein interactions | 5108 | 240 | 61 | 17029 | 2761 |
PPIB,FGFR1OP,MAPRE1,EWSR1,MCM10,LUZP1,DYNLL1,RAE1,MAGED1,STRN4,NUF2,SECISBP2,HAUS4,CCNB1,CSNK1A1,HAUS2,ANKRD26,CEP104,NOL11,CCP110,CENPJ,KIF14,TXLNA,GPATCH1,CEP63,TP53BP2,POC5,MOB4,PLK1,PPP1R9B,STAU1,CCDC138,CDC123,FOPNL,CAMSAP1,RRM2,CKAP2L,BICD2,TANC1,COMMD4,ERC1,DAPK3,HAUS8,PPP2CA,TSC1,TTLL4,CCDC14,E2F4,ODF2,CEP55,EXOC4,KIAA1328,YWHAZ,FUS,BTF3,MYO9A,IDH3B,SASS6,CCNB2,ECPAS,CSNK1D |
| 1.597e-04 | -8.74 | GCM_PPP1CC | MSigDB lists | GCM_PPP1CC | 53 | 19 | 17377 | 2626 |
HMGN1,NASP,SUMO2,NACA,PSMA1,SNRPD3,EIF4G2,CBFB,SNRPA,ERH,NAP1L1,DUT,PPP1R8,SRSF4,CAPZA1,TRA2B,TCEA1,CFL1,HNRNPM |
| 1.602e-04 | -8.74 | TRIM55 (tripartite motif containing 55) | protein interactions | 84675 | 91 | 29 | 17029 | 2761 |
UBE2D3,SRSF11,USP7,DCAF6,ATXN3,SF3B6,DHX9,BRAP,USP39,ATP5F1B,SEPT7,PCGF1,UBE2I,STAM,MRPL19,SRSF1,USP5,UCHL5,SAFB,E2F4,GMEB1,BUD31,PIAS2,ESPL1,RNF114,SRSF10,USP13,CDC5L,PRPF19 |
| 1.602e-04 | -8.74 | POLR2G (RNA polymerase II subunit G) | protein interactions | 5436 | 91 | 29 | 17029 | 2761 |
CTDP1,POLR2I,EWSR1,RPRD1A,MCM10,NASP,POLR2G,POLR2L,PPP1R2,POLR2K,VHL,ELOA,MOGS,POLR2D,BRCA1,PRKRA,PSMB9,CDC73,POLR2A,WDR48,GTF2F1,PAF1,MED10,POLR2J,MED15,CTR9,TCEA1,MCPH1,RPRD1B |
| 1.605e-04 | -8.74 | mitochondrial respiratory chain complex assembly | biological process | GO:0033108 | 92 | 28 | 17256 | 2622 |
COA3,NDUFA5,NDUFV2,NDUFS1,NDUFB6,TIMMDC1,NDUFAF2,UQCR10,TMEM126B,DMAC2,TIMM21,NDUFA7,NDUFB1,TAZ,FOXRED1,NDUFS7,NDUFS4,NDUFAF6,FASTKD3,NDUFV1,NDUFA2,NDUFB4,NDUFA11,NDUFB9,NDUFS8,NDUFS5,NDUFA3,SLC25A33 |
| 1.605e-04 | -8.74 | GAZDA_DIAMOND_BLACKFAN_ANEMIA_MYELOID_DN | MSigDB lists | GAZDA_DIAMOND_BLACKFAN_ANEMIA_MYELOID_DN | 37 | 15 | 17377 | 2626 |
CD59,COX5B,POLR2I,CHMP4A,LUZP1,EID1,UROD,RAB4A,PQBP1,RPL15,PXMP2,DCLRE1C,MAPK1,RYBP,RPL36 |
| 1.605e-04 | -8.74 | STONER_ESOPHAGEAL_CARCINOGENESIS_UP | MSigDB lists | STONER_ESOPHAGEAL_CARCINOGENESIS_UP | 37 | 15 | 17377 | 2626 |
TXNL1,USO1,PDCD10,H2AFZ,PSMA6,GOLGA7,DDX5,SEPT7,RAB1A,AP3S1,FTSJ3,ATP6V0E1,SPSB3,TMED2,RLIM |
| 1.612e-04 | -8.73 | C11orf58 (chromosome 11 open reading frame 58) | protein interactions | 10944 | 46 | 18 | 17029 | 2761 |
EWSR1,HMGN5,WDR1,SF3B1,PSMB7,LDHA,RANGAP1,MYL6B,BZW2,MARK2,WDR48,GNS,NAP1L1,SHC1,SLC44A1,RPLP1,RNF19A,AHCYL1 |
| 1.612e-04 | -8.73 | BLMH (bleomycin hydrolase) | protein interactions | 642 | 46 | 18 | 17029 | 2761 |
PDPK1,USP7,RPL29,MAPRE1,CYLD,WDYHV1,TRIO,GORASP2,MCM2,UBE2I,ANLN,APP,RPL11,SYNCRIP,LIMK1,KBTBD7,SH3GLB2,USP53 |
| 1.617e-04 | -8.73 | regulation of cytokinesis | biological process | GO:0032465 | 83 | 26 | 17256 | 2622 |
PLK1,PLK3,KIF3B,RHOA,PKP4,KLHL21,CUL3,KIF23,CDC6,RACGAP1,AURKB,BCL2L1,BECN1,RAB11A,SH3GLB1,CALM2,PDXP,AHCTF1,CCP110,CDC42,KIF14,PIN1,PRC1,NUP62,VPS4A,CDC25B |
| 1.624e-04 | -8.73 | POLR2B (RNA polymerase II subunit B) | protein interactions | 5431 | 113 | 34 | 17029 | 2761 |
CTDP1,LZTR1,POLR2K,SUZ12,ATP6V1B2,GTF2F1,SUB1,MED10,INTS1,RPAP1,CTR9,TCEA1,POLR1B,ASB6,RPRD1B,DCTN1,RPAP3,POLR2I,POLR2L,POLR2G,POLR2D,CUL3,ELOA,WDR82,MEN1,PSMB9,POLR2A,CAND1,POLR2J,BRD2,RUVBL2,BTF3,TUBB,IFI16 |
| 1.632e-04 | -8.72 | SNCA (synuclein alpha) | protein interactions | 6622 | 211 | 55 | 17029 | 2761 |
USP7,NDUFB6,ANXA6,ZCCHC8,DYNLL1,ENSA,KLC1,CSNK2A1,CYCS,BCL2L1,DNAJB1,AP1B1,CSNK1A1,LYN,SRRT,APP,PARK7,RAB8A,GRK2,IARS,SIAH1,MCM5,PIN1,DNAAF2,SRSF4,EFTUD2,SRI,PRPF19,PLK3,PLK1,SNRNP200,POLR2L,VDAC2,GBA,SMU1,ILF3,MEF2D,FXR1,ELK1,VDAC1,EIF3G,ARHGAP15,PRDX1,MAPK3,HSPA4,PRDX3,LAMTOR4,SIAH2,ACTB,PSAP,MAPK1,YWHAH,CBX4,TUBB,CSNK1D |
| 1.639e-04 | -8.72 | AACYNNNNTTCCS_UNKNOWN | MSigDB lists | AACYNNNNTTCCS_UNKNOWN | 88 | 27 | 17377 | 2626 |
IMMT,CDC40,TRIP10,PHF23,POC1A,PCGF6,PHF6,PSMC4,PRIM1,RPL23A,DDX23,NUCB1,KLHL20,RPS27A,CCDC6,ETV6,ARNTL,MRPL34,NUP62,MDH1,NUP153,POLR1B,PURA,OGG1,TMEM33,SAP30,PRPF19 |
| 1.640e-04 | -8.72 | cell adhesion molecule binding | molecular function | GO:0050839 | 483 | 104 | 17224 | 2647 |
EXOC3,WASF2,ADD1,RAB11B,ADAM10,CAST,ANK3,OLA1,MYH9,SND1,S1PR2,PCBP1,LYN,TWF2,KTN1,PARK7,RPL23A,DST,CRKL,PPME1,EIF5,LRRC59,ABI1,RPL29,USO1,SEPT9,NCK1,EZR,CADM1,ERBIN,ANLN,CHMP2B,RAB1A,ERC1,GLOD4,AFDN,AHNAK,STK38,SH3GLB2,STAT1,ITGB1,ATXN2L,ADAM9,CHMP4B,RPS26,NUMB,PFKP,CSNK1D,ADAM23,RPS2,MAPRE1,SCYL1,RPL15,ARFIP2,ARGLU1,DNAJB1,PSEN1,PDXDC1,BZW2,FERMT3,PTPN2,KIF5B,VASP,ATIC,AHSA1,PTPN11,CAPZA1,TENM3,CNN2,TAGLN2,LYPLA2,EEF1D,NUDC,SPTAN1,ADAM17,SNX2,DHX29,RPL6,LDHA,RANGAP1,PLEC,EIF2A,ICAM2,PKM,SEPT7,EIF4G2,MACF1,EIF4H,MARK2,CCT8,PICALM,PRDX1,CIP2A,SH3GLB1,PDLIM1,GOLGA2,LTBP4,YWHAZ,EHD4,CD81,CCNB2,PDLIM5,ZC3HAV1,ESYT2 |
| 1.649e-04 | -8.71 | WD40/YVTN_repeat-like_dom_sf | interpro domains | IPR015943 | 329 | 74 | 18492 | 2768 |
CORO7,PLXNC1,COPA,TRAF7,WDR13,POC1A,WDTC1,PLXNA1,GNB2,RIC1,UTP18,FBXW2,TAF5L,CORO1A,UTP4,STRAP,SEH1L,CSTF1,WDR41,PRPF19,MLST8,MIOS,LRBA,SMU1,WDHD1,WDR82,EML4,GEMIN5,BRWD1,WDR11,SCAP,HPS5,TBL3,CORO1C,WDR59,WDR4,WDR7,PRPF4,DMWD,PPP2R2D,DCAF5,AAAS,WSB2,CDC40,RAE1,STRN4,WDR5,COPB2,WDR48,RFWD3,DTL,DCAF6,DCAF8,WDR1,WDR18,UTP15,WDR81,PPWD1,EIF2A,ARPC1A,RMC1,SEC31A,PLAA,PALB2,DCAF11,WIPI2,WDR76,WDR62,WDR91,RBBP4,WDR45B,BRWD3,ANAPC4,DDB1 |
| 1.651e-04 | -8.71 | SGK1 (serum/glucocorticoid regulated kinase 1) | protein interactions | 6446 | 70 | 24 | 17029 | 2761 |
PDPK1,TSC22D3,RAF1,GADD45G,TUFM,AKT1S1,SYVN1,ARL5B,FOXO3,PPP2CA,TMEM184C,PA2G4,PDK2,HSPA4,NEK6,IARS,PIN1,CDKN1B,FKBP5,YWHAZ,KPNA2,CREB1,HRAS,CDC37 |
| 1.651e-04 | -8.71 | LMAN1 (lectin, mannose binding 1) | protein interactions | 3998 | 70 | 24 | 17029 | 2761 |
CLPTM1,COPA,PHB2,COPE,TUFM,TMEM216,MCFD2,BCAP31,APP,HLA-A,COPB2,SSR1,STOML2,PDCD6,ATP1A1,ATP2A2,TMED10,LRPPRC,YBX1,BCAP29,ATP5F1A,CYC1,TMX1,TMED2 |
| 1.651e-04 | -8.71 | NME1 (NME/NM23 nucleoside diphosphate kinase 1) | protein interactions | 4830 | 70 | 24 | 17029 | 2761 |
MIF,RORB,NQO1,KAT2A,WDYHV1,WDR1,DYNLL1,UROD,RAC1,GORASP2,BRCA1,MCM2,DUSP22,MAPK14,PTEN,PRDX5,ITGB1,TNPO2,TERF1,STRAP,EYA2,CFL1,SMARCD1,FUBP1 |
| 1.652e-04 | -8.71 | BOYAULT_LIVER_CANCER_SUBCLASS_G23_UP | MSigDB lists | BOYAULT_LIVER_CANCER_SUBCLASS_G23_UP | 49 | 18 | 17377 | 2626 |
H2AFZ,KIAA0100,SUZ12,DBF4,MKI67,NARF,RRM1,SLBP,SMC2,MCM2,ARPC1A,SLC50A1,TFRC,OIP5,IARS,DDOST,SLC26A2,MAPK1 |
| 1.652e-04 | -8.71 | TBK1.DN.48HRS_DN | MSigDB lists | TBK1.DN.48HRS_DN | 49 | 18 | 17377 | 2626 |
KIAA0100,RGS2,DUSP22,H2AFV,ABCF1,CPNE3,PDHX,BIRC2,ANKRD10,TERF2IP,RAD51C,ATP6V1D,RALB,BIRC5,ATG3,DCK,AKAP8,BCL2 |
| 1.654e-04 | -8.71 | GO_RAS_PROTEIN_SIGNAL_TRANSDUCTION | MSigDB lists | GO_RAS_PROTEIN_SIGNAL_TRANSDUCTION | 140 | 38 | 17377 | 2626 |
WASF2,RHOG,NF1,BRAP,MYO9B,NCKAP1,MAPK14,RAPGEF6,PARK7,RTKN,CRKL,RB1,RAP1A,CCNA2,SHC1,RALB,ARHGEF1,RAB4A,DNMT1,CFL1,CYFIP1,SHOC2,NRAS,RHOA,MAPKAPK3,RFXANK,KRAS,RIT1,TRIM28,RHOB,GNA12,ELMO1,LIMK1,ROCK1,CDK2,HRAS,CDKN2A,ALS2 |
| 1.654e-04 | -8.71 | PDGF_UP.V1_UP | MSigDB lists | PDGF_UP.V1_UP | 140 | 38 | 17377 | 2626 |
PPP1R37,NDUFS1,TRIP12,URB2,AGFG1,SNRPD3,FKBP2,SLC20A1,CHKA,TET3,RAB35,ATP6V0A2,JOSD1,CLDND1,MOB1A,NRAS,KLF10,ELP4,PFKFB3,EZR,CDC6,UTP3,CAPZA2,BICD2,GLOD4,PAF1,UAP1,ETS2,PARG,MAPK6,FAM3C,ADAM9,ATF6,TAF12,TRAF5,RNF14,CBX4,ZBTB24 |
| 1.665e-04 | -8.70 | GSE42088_UNINF_VS_LEISHMANIA_INF_DC_24H_UP | MSigDB lists | GSE42088_UNINF_VS_LEISHMANIA_INF_DC_24H_UP | 200 | 50 | 17377 | 2626 |
MANBA,TSC22D3,FAM53C,CAST,SF3B1,TOR3A,NACA,TRAK1,TKT,CERK,ACAP1,LETMD1,ASAH1,ADPGK,RGS2,HMG20A,MXD1,CHKA,CSDE1,GSTK1,ARHGEF1,H2AFY,SUCLG2,PCBP2,KCNAB2,CSNK1G3,AMPD2,CSNK1G2,CLCN3,RFC3,PIGT,TACC1,SUGP2,MTMR12,KCNQ1,SRSF5,MTX1,TAZ,RHOB,MAN2A2,DNAJC10,SGSH,MID1IP1,QARS,CCDC69,ZDHHC7,HMGB2,GALNT10,LTA4H,RNF114 |
| 1.674e-04 | -8.69 | SENESE_HDAC3_TARGETS_DN | MSigDB lists | SENESE_HDAC3_TARGETS_DN | 480 | 102 | 17377 | 2626 |
MON1B,UBE2Z,TGOLN2,UBE2I,COMMD8,EXT2,PAIP1,ATPAF1,C2orf68,BRPF3,CDC42,GLIS2,KIF14,ATP13A3,APOOL,CLN6,SAP30L,DRAM2,SEH1L,CARM1,ADCY7,RYBP,SNX8,ORAI2,ULK3,PSRC1,ZNF559,ATG9A,EID1,FOPNL,SLC16A7,LACTB,ARHGDIB,ASF1B,VEZF1,ALDH3B1,TRAM2,AHNAK,TMED10,RAB24,GADD45B,H2AFX,ANP32E,GALNT10,NCOA1,PDXK,MAPK1,XRCC4,ATMIN,PARD3,NCOR2,MIF4GD,CDC40,PKP4,MECP2,TCF3,GNE,TMX3,SDC2,HAUS4,SLC25A43,MFSD10,CHKA,EBP,TNS3,NFATC3,ADD3,CLIC4,C4orf3,ZDHHC13,FEM1B,ANP32A,CTR9,MDFIC,N4BP2,PDLIM2,NIPAL3,TK1,HMGN5,TSPAN31,EMB,KIAA0930,ACSL3,MYBL2,FBXO9,UHRF1BP1,NFATC2IP,SEPT7,C9orf40,NEU1,ATAD2,PDLIM1,BIRC5,CDCA7L,FAM3C,BBX,TFDP1,CEBPG,TBPL1,SPCS3,TSEN15,ADNP2 |
| 1.678e-04 | -8.69 | mucoepidermoid_carcinoma | COSMIC cancer mutations | mucoepidermoid_carcinoma | 94 | 28 | 17385 | 2587 |
EXOC3,EWSR1,NRAS,CHTF18,SF3B1,CHCHD2,KRAS,PRMT2,PRKRA,ITGB5,EML4,MFSD10,KIF5B,DST,ERV3-1,TMEM41A,PTEN,CCDC6,TMEM99,LTN1,STK11,GEMIN4,TOP1MT,MVP,PDCD11,SMAD4,HRAS,CDKN2A |
| 1.679e-04 | -8.69 | MODULE_403 | MSigDB lists | MODULE_403 | 45 | 17 | 17377 | 2626 |
PLK1,PCNA,TK1,H2AFZ,CHD3,TFDP1,MKI67,MYBL2,MSH2,E2F1,KPNA2,XRCC3,CDC25B,CCNB1,CDK2,RPA1,XRCC5 |
| 1.683e-04 | -8.69 | STIP1 (stress induced phosphoprotein 1) | protein interactions | 10963 | 173 | 47 | 17029 | 2761 |
HSPH1,NPHP4,EWSR1,TXN,TKT,DNAJB1,TAF6L,STMN1,PCBP1,APP,PRNP,CDK5,EIF2S2,PTEN,AHSA1,DUT,AKR1B1,FNIP2,TAGLN2,PTGES3,AHCYL1,ATF2,PPA1,PCBP2,GPX4,CDC37,PTPN18,NASP,EZR,GLO1,BRCA1,MCM2,HSPA1B,EVC2,HSPA4,AHNAK,HINT1,CCDC14,HNRNPH3,ACLY,FKBP5,XRCC3,PPP5C,IGBP1,HNRNPDL,POT1,SSSCA1 |
| 1.685e-04 | -8.69 | GO_COPI_COATED_VESICLE_MEMBRANE | MSigDB lists | GO_COPI_COATED_VESICLE_MEMBRANE | 16 | 9 | 17377 | 2626 |
TMED7,COPA,COPE,SCYL1,TMED3,COPG2,COPB2,TMED2,KDELR1 |
| 1.685e-04 | -8.69 | GO_U2_TYPE_PRESPLICEOSOME | MSigDB lists | GO_U2_TYPE_PRESPLICEOSOME | 16 | 9 | 17377 | 2626 |
LUC7L3,SF3B1,SNRPB,SNRPG,PRPF39,SNRNP70,LUC7L,SF3A2,LUC7L2 |
| 1.688e-04 | -8.69 | HIRSCH_CELLULAR_TRANSFORMATION_SIGNATURE_UP | MSigDB lists | HIRSCH_CELLULAR_TRANSFORMATION_SIGNATURE_UP | 231 | 56 | 17377 | 2626 |
SLC12A7,IER2,MRPL9,IVNS1ABP,YTHDC2,HEXB,TAP1,RRAGC,AGFG1,BCL2L1,RGS2,EIF1B,MAPK14,STAM,CREM,ANKRD28,PTPN2,SLC1A4,TNFAIP8,FUT8,ZNF200,ARHGEF2,PIKFYVE,STAT3,HTRA2,IFRD1,CYTH1,PGS1,OXR1,LYRM1,ACSL3,NARF,PCGF1,MPG,MAK16,ANKRD46,RPL36,DTWD1,SLCO4A1,GALNT2,MID1IP1,UAP1,FBXO28,ETS2,TAB2,SNAP23,CTBS,SIAH2,APPL2,CANT1,MAP3K5,EHD4,ZNF45,HEXA,ABCA1,EGLN1 |
| 1.689e-04 | -8.69 | endoplasmic reticulum-Golgi intermediate compartment | cellular component | GO:0005793 | 123 | 34 | 18223 | 2701 |
TMED7,GNPNAT1,GORASP1,SCYL1,TAP1,TMED3,BCAP31,COPG2,MAN1A1,PTPN2,CD59,VMP1,TAP2,YIF1B,MYDGF,LMAN1,SLC35C2,PDIA6,TMED2,KDELR1,CHP1,MCFD2,STK17B,YIF1A,NUCB1,SEC23IP,GOLGA2,SURF4,TMED10,MYO18A,ERGIC3,PIEZO1,ECPAS,CSNK1D |
| 1.689e-04 | -8.69 | LEO1 (LEO1 homolog, Paf1/RNA polymerase II complex component) | protein interactions | 123169 | 50 | 19 | 17029 | 2761 |
DNMT3A,POLR2G,DCTN2,ELOA,CSNK2A1,RTF1,CDK11A,CDC73,POLR2A,SUPT16H,ANKRD28,PAF1,HADHB,PTPN11,CTR9,TCEA1,TOP1MT,ARRB2,SSRP1 |
| 1.689e-04 | -8.69 | Eif3i (eukaryotic translation initiation factor 3, subunit I) | protein interactions | 54709 | 50 | 19 | 17029 | 2761 |
EIF3L,DDX47,EIF3D,TEX10,HNRNPUL2,WDR18,EIF4G2,EIF3G,CCT8,EIF3H,EIF3A,RPL23A,SUPT16H,EIF3K,UTP18,WDR76,STRAP,CBX4,MSH6 |
| 1.689e-04 | -8.69 | NUDCD2 (NudC domain containing 2) | protein interactions | 134492 | 50 | 19 | 17029 | 2761 |
PTMS,NPHP4,XIAP,PSMB7,STMN1,PSMD9,GINS4,EVC2,HERC3,CEP104,NUP210,SEC23IP,PDRG1,OSTF1,PTGES3,IGBP1,TERF1,POT1,RNF114 |
| 1.689e-04 | -8.69 | SCYL2 (SCY1 like pseudokinase 2) | protein interactions | 55681 | 50 | 19 | 17029 | 2761 |
COX15,SARNP,TKT,GTF3A,GORASP2,CNTROB,SEPT7,VDAC1,SH3GLB1,CDK5,SUB1,PDLIM1,EIF4A3,SEPT11,GTSE1,TALDO1,ARRB2,PCBP2,CDC5L |
| 1.691e-04 | -8.69 | NEP/NS2 Interacts with the Cellular Export Machinery | REACTOME pathways | R-HSA-168333 | 31 | 14 | 10287 | 1696 |
NDC1,NUP188,NUP210,RAE1,NUP107,NUP54,NUP62,NUP153,NUP155,NUP85,NUP58,SEH1L,AAAS,NUP205 |
| 1.691e-04 | -8.69 | Regulation of Glucokinase by Glucokinase Regulatory Protein | REACTOME pathways | R-HSA-170822 | 31 | 14 | 10287 | 1696 |
NDC1,NUP188,NUP210,RAE1,NUP107,NUP54,NUP62,NUP155,NUP153,NUP85,NUP58,AAAS,NUP205,SEH1L |
| 1.692e-04 | -8.68 | negative regulation of cellular catabolic process | biological process | GO:0031330 | 235 | 57 | 17256 | 2622 |
USP7,FEZ2,TSC2,KDM4A,PHF23,DAP,UBXN1,DHX9,SECISBP2,THRAP3,SIRT2,BECN1,MAPK14,PARN,PSEN1,RIC1,PARK7,PAIP1,RPL11,TIGAR,TBC1D14,AXIN2,BCL2,YBX1,TARDBP,STAT3,SENP1,PABPC1,HTRA2,PDCL3,RNF5,RYBP,UBQLN4,LARS,TIMP2,PBK,CIRBP,MCL1,EIF4G2,USP36,TSC1,CHMP4A,SYNCRIP,GOLGA2,TAB2,HIPK2,LRPPRC,E2F1,OGT,PML,CHMP4B,CTSA,ROCK1,SNRNP70,TOB1,EGLN1,SVIP |
| 1.695e-04 | -8.68 | BIOCARTA_P27_PATHWAY | MSigDB lists | BIOCARTA_P27_PATHWAY | 13 | 8 | 17377 | 2626 |
RB1,RBX1,TFDP1,E2F1,CDKN1B,CUL1,CDK2,UBE2M |
| 1.695e-04 | -8.68 | REACTOME_ASSOCIATION_OF_LICENSING_FACTORS_WITH_THE_PRE_REPLICATIVE_COMPLEX | MSigDB lists | REACTOME_ASSOCIATION_OF_LICENSING_FACTORS_WITH_THE_PRE_REPLICATIVE_COMPLEX | 13 | 8 | 17377 | 2626 |
CDC6,ORC1,ORC3,E2F2,RPS27A,CDT1,E2F1,E2F3 |
| 1.696e-04 | -8.68 | positive regulation of protein modification by small protein conjugation or removal | biological process | GO:1903322 | 125 | 35 | 17256 | 2622 |
RPS2,PHF23,GORASP1,XIAP,UBE2I,DCUN1D4,BIRC2,FANCI,WDR48,FBXO5,FKBP1A,PTEN,MTA1,PIN1,TANK,CTR9,PLK1,BIRC3,CUL3,TOPORS,BRCA1,ADRB2,DCUN1D5,PTTG1IP,RAB1A,TOLLIP,PEF1,DERL1,HSPBP1,PDCD6,GOLGA2,AXIN1,TICAM1,UBE2C,ARRB2 |
| 1.699e-04 | -8.68 | ADAR (adenosine deaminase, RNA specific) | protein interactions | 103 | 66 | 23 | 17029 | 2761 |
COX15,STAU1,THOC1,SNRPB,SUZ12,CUL3,DHX9,SMC2,UBE2I,MATR3,CAND1,RPA1,DDX17,RPA2,UPF1,MEX3C,XRCC3,TARDBP,CRY2,RBPJ,IFI16,HNRNPM,TACC3 |
| 1.699e-04 | -8.68 | MRPL41 (mitochondrial ribosomal protein L41) | protein interactions | 64975 | 66 | 23 | 17029 | 2761 |
MRPL9,MRPL42,MRPL39,MRPL12,ILF3,MRPL16,OGDH,MRPL19,CAND1,MRPL50,MRPL55,MRPL27,FAM3C,MRPL34,MRPL40,MRPL48,PREPL,MRPL11,MRPL13,MRPL3,MRPL32,MRPL57,FUBP1 |
| 1.699e-04 | -8.68 | Eukaryotic Translation Initiation | REACTOME pathways | R-HSA-72613 | 125 | 37 | 10287 | 1696 |
RPS15,RPS2,RPLP2,EIF3D,RPL15,RPL11,RPL23A,EIF2S2,RPL17,RPL19,EIF5,RPL22L1,PABPC1,EIF3L,RPL29,RPL35,RPL8,RPL38,RPL6,RPS10,RPS24,RPL27A,EIF4H,EIF3G,RPS9,EIF3H,EIF3A,RPSA,RPL36,EIF3K,RPL37,RPL32,RPS27A,RPS14,RPLP1,FAU,RPS26 |
| 1.699e-04 | -8.68 | Cap-dependent Translation Initiation | REACTOME pathways | R-HSA-72737 | 125 | 37 | 10287 | 1696 |
RPS15,RPS2,RPLP2,EIF3D,RPL15,RPL11,RPL23A,EIF2S2,RPL17,RPL19,EIF5,RPL22L1,PABPC1,EIF3L,RPL29,RPL35,RPL8,RPL38,RPL6,RPS10,RPS24,RPL27A,EIF4H,EIF3G,RPS9,EIF3H,EIF3A,RPSA,RPL36,EIF3K,RPL37,RPL32,RPS27A,RPS14,RPLP1,FAU,RPS26 |
| 1.705e-04 | -8.68 | Sf3a1 (splicing factor 3a, subunit 1) | protein interactions | 67465 | 35 | 15 | 17029 | 2761 |
RBM17,DNAJC8,CHERP,SF3B1,SNRPB,SF3B6,U2SURP,SNRPG,SNRPD3,SMURF1,TTC33,SF3A2,DHX15,DDX42,SF3B2 |
| 1.705e-04 | -8.68 | GSE39820_CTRL_VS_TGFBETA3_IL6_IL23A_CD4_TCELL_UP | MSigDB lists | GSE39820_CTRL_VS_TGFBETA3_IL6_IL23A_CD4_TCELL_UP | 190 | 48 | 17377 | 2626 |
HSPH1,COX15,HECA,CDC40,HNRNPAB,KRBA1,SHPRH,SF3B1,XIAP,DHX9,TFRC,SF3B2,UBXN2A,CCP110,INTS7,WDR44,RABGAP1L,LPIN2,NUP107,PTPN11,FEM1B,ZFYVE27,ZNF770,MORC3,TTPAL,TEX10,E2F3,WDHD1,DNAJA1,PPWD1,BORA,ARMC8,CBFB,FKBP3,MAT2A,KRIT1,ELMO1,ZNF367,CDCA5,ZNF436,OGT,DVL1,NAA20,RBBP4,PTDSS1,FAF1,GPATCH4,ESYT2 |
| 1.705e-04 | -8.68 | GSE9037_CTRL_VS_LPS_4H_STIM_BMDM_UP | MSigDB lists | GSE9037_CTRL_VS_LPS_4H_STIM_BMDM_UP | 190 | 48 | 17377 | 2626 |
RAB14,RPLP2,ANKH,HABP4,SUMF1,GLUD1,UBQLN2,AP1B1,IKBIP,MAPK14,RUFY1,PARK7,CAPN2,CTSS,MBD2,PPCDC,SOCS6,HADHB,ABCD1,RP2,MRPL11,CNOT6L,MGAT5,MYO5A,PDLIM2,TCTEX1D2,SNX2,PBXIP1,TACC1,SIGMAR1,ACSL3,PARP4,AP4E1,RFC2,STK17B,SPPL2B,BBS12,DHX57,BTBD1,RPA1,RBM47,WDR11,CCDC6,ACLY,MEGF9,MDH1,YWHAH,ANAPC4 |
| 1.705e-04 | -8.68 | GSE15330_WT_VS_IKAROS_KO_GRANULOCYTE_MONOCYTE_PROGENITOR_UP | MSigDB lists | GSE15330_WT_VS_IKAROS_KO_GRANULOCYTE_MONOCYTE_PROGENITOR_UP | 190 | 48 | 17377 | 2626 |
MIF,HIVEP3,KARS,H2AFZ,MRPL39,UQCR10,LYRM2,HDDC2,CNOT3,DDRGK1,NUDT19,PRKD3,PCNA,CTSS,THAP4,RCSD1,PTPN11,MDFIC,NDUFS8,TCEA1,LMAN1,NCOA2,MLST8,EBAG9,LACTB,PSMA1,PSMG1,ADSL,MRPL16,CADM1,FOXRED1,MRPS14,FAS,GLOD4,HLA-B,HSPBP1,RBMX,MYO18A,ITGB1,APPL2,SOCS4,ZRANB2,GALNT10,CHEK2,TRAF5,CD81,CBX4,ZC3HC1 |
| 1.705e-04 | -8.68 | GSE43955_1H_VS_42H_ACT_CD4_TCELL_UP | MSigDB lists | GSE43955_1H_VS_42H_ACT_CD4_TCELL_UP | 190 | 48 | 17377 | 2626 |
IER2,GPR132,RWDD1,MRPS15,UROD,UCK2,VTI1A,RAB23,SIRT2,PITHD1,MBD4,NFATC3,RAB4A,MECR,CTR9,CDKN1B,CPSF4,SLC35C2,NSUN4,PRIM2,HARS,ERF,RAB7A,CAMSAP1,GBA,PSMB7,TBRG4,MRPS10,EIF2AK1,ADRB2,NDRG3,GFER,NECAP2,FBXO21,KPNA4,EIF4ENIF1,NSF,RBL1,PARG,CDCA7L,ST3GAL2,TCOF1,BTF3,BRWD3,CD81,EYA2,TSPAN5,TMEM131 |
| 1.705e-04 | -8.68 | GSE43863_TFH_VS_LY6C_INT_CXCR5POS_EFFECTOR_CD4_TCELL_UP | MSigDB lists | GSE43863_TFH_VS_LY6C_INT_CXCR5POS_EFFECTOR_CD4_TCELL_UP | 190 | 48 | 17377 | 2626 |
WSB2,IER2,ADAM10,SRSF6,SRGN,EIF3D,RBM8A,C5orf30,RRAGC,JMJD6,ARF1,WDR5,C19orf48,SLC20A1,TMEM165,DDRGK1,HNRNPA2B1,FARSA,ERH,SLC31A1,SAR1A,FOXN2,AFF1,LRRC59,ATP6V0D1,NASP,POLR2L,NSUN2,USP10,TOR1AIP2,KRAS,DNAJA1,TOMM40,ZFAND5,GOSR1,SNRPA,PRDX1,NMT2,ETS2,PDRG1,STAT6,BCL7C,SIAH2,ATE1,NUP62,PDXK,BYSL,CSNK1D |
| 1.705e-04 | -8.68 | GSE45365_HEALTHY_VS_MCMV_INFECTION_CD8A_DC_IFNAR_KO_DN | MSigDB lists | GSE45365_HEALTHY_VS_MCMV_INFECTION_CD8A_DC_IFNAR_KO_DN | 190 | 48 | 17377 | 2626 |
UBE2D3,CTDP1,CDS2,HNRNPAB,TAP1,YTHDF3,USP39,OAT,PSEN1,FOXO3,MXD1,CFLAR,PTPN2,ABL2,SP100,DDA1,ATP13A3,ZCCHC2,NAA50,RNF19A,TALDO1,HNRNPM,CDC37,ACSL5,ELL2,SNRPB,DENND1B,E2F3,MAP7D1,PRPF3,ICAM2,SHCBP1,DDX39A,LUC7L,PICALM,RHEB,PAF1,VEZF1,RBM47,TFE3,GADD45B,STAT1,TICAM1,NCOA1,CLN3,H3F3A,APOL2,ZC3HAV1 |
| 1.705e-04 | -8.68 | GSE41978_ID2_KO_VS_ID2_KO_AND_BIM_KO_KLRG1_LOW_EFFECTOR_CD8_TCELL_DN | MSigDB lists | GSE41978_ID2_KO_VS_ID2_KO_AND_BIM_KO_KLRG1_LOW_EFFECTOR_CD8_TCELL_DN | 190 | 48 | 17377 | 2626 |
MIF,KIAA0100,SRGN,GNE,CHCHD2,ARF1,POLR3K,RPL11,RPL23A,PDCD10,RPL17,GOT2,GMEB1,RPN2,YBX1,RPL19,CORO1A,NAP1L4,PABPC1,CFL1,ENPP4,RPL35,SEC61B,GABPA,RPL38,LDHA,RPL6,MRPL43,RPS10,UBE2V1,EAF2,SRSF5,RPL27A,ZFAND5,EIF4H,RPSA,RPA1,RAB18,SEC61A1,ZFP92,RPS14,RPLP1,COX5A,DDX5,FAU,RPS26,ATMIN,TUBB |
| 1.706e-04 | -8.68 | CDC20 (cell division cycle 20) | protein interactions | 991 | 159 | 44 | 17029 | 2761 |
CLSPN,CDT1,PTTG1,SIRT2,CCNB1,APP,MAD2L2,FBXO5,PCNA,CCNA2,HUWE1,AXIN2,YBX1,ANAPC7,CDC25B,CDC5L,PLK1,CCT2,STAU1,TK1,HNRNPF,ANAPC2,CDC6,AURKB,USP22,PBRM1,EIF2A,CDC23,CCNF,CCT8,PPP2CA,KIF18A,CDC16,PPP2R5A,CDC27,TFDP1,E2F1,CDK2,UBE2C,CCDC59,TUBB,HDAC2,SSSCA1,ANAPC4 |
| 1.708e-04 | -8.68 | RPL26 (ribosomal protein L26) | protein interactions | 6154 | 100 | 31 | 17029 | 2761 |
RPS15,COX15,RPL35,RPLP2,RPL6,RPL38,RPL8,DHX8,RPL15,MCM2,BRIX1,SDHA,RPS9,RPL36,CAND1,DDX56,APLP2,ZNF317,MDM2,EIF4A3,HNRNPR,RPL17,RPS14,TARDBP,RPL19,SNRNP70,CDK2,ARRB2,RPS26,USP53,ZC3HAV1 |
| 1.708e-04 | -8.68 | ATP5PO (ATP synthase peripheral stalk subunit OSCP) | protein interactions | 539 | 100 | 31 | 17029 | 2761 |
UNK,STAU1,PPT1,COQ8A,SUZ12,RAB7A,RPS10,VDAC2,ATP6V0A1,NDUFA4,COX4I1,ATP5F1B,ADRB2,MCM2,VDAC1,ATP5PF,APP,MAD2L2,NDUFS4,SURF4,GRSF1,ZNF746,NDUFB9,BCAP29,CYC1,ATP5F1A,APOOL,CDK2,ATF2,CD81,ATP6V0D1 |
| 1.708e-04 | -8.67 | TMTCGCGANR_UNKNOWN | MSigDB lists | TMTCGCGANR_UNKNOWN | 150 | 40 | 17377 | 2626 |
UBE2D3,SKA3,GGNBP2,PIGN,PPP1R12A,ZFP91,MDH2,DCTN2,FAM76A,MAPK14,CNOT3,CSDE1,NOL11,WDR44,RPL17,EIF5,ATF2,SLC12A2,LRSAM1,CDK12,FGFR1OP2,LUC7L2,CDC5L,TAOK1,SRSF5,SEPT7,ICMT,STYXL1,CCT8,MATR3,PRDX1,CAND1,HSPA4,HNRNPH3,NDUFA11,UHRF2,CENPT,RBPJ,PURA,ANAPC4 |
| 1.709e-04 | -8.67 | GO_ENDOSOME | MSigDB lists | GO_ENDOSOME | 742 | 148 | 17377 | 2626 |
MIB2,CCDC93,RAB14,PTP4A3,TGOLN2,BECN1,RUFY1,KIFC1,RAB8A,RAP1A,RABGAP1L,RAB35,RAB4A,DNM2,AP2B1,ZFYVE27,MARCH2,ATG9A,AKT2,EZR,RAB5B,RAB22A,PLEKHF2,OPTN,GRIPAP1,RPS27A,ITGB1,ATP6V0C,VPS4A,CLN3,ATP6V0E1,NUMB,STARD3NL,UBE2D3,TBC1D12,TMUB1,SCOC,GGA1,HLA-E,RAB23,LAMTOR3,ACAP1,TMEM165,VPS25,WDR48,SLC31A1,ZNRF2,SNX18,ATP6V0A2,PIKFYVE,ATP6V0D1,VOPP1,USP10,ADRB2,MAP2K2,APPL1,RHOB,PI4K2A,DERL1,OSBPL11,SIAH2,APPL2,EHD4,CDK2,SNX14,ZC3HAV1,NIPA1,ALS2,WASF2,ANKRD27,CYTIP,CHMP2A,SNX27,GNPNAT1,RAB11B,RAC1,VTI1A,RRAGC,ZFYVE21,NIPA2,APP,STAM,CD320,CRKL,ATP6V0B,RAB21,SHC1,MTMR4,WDR44,SIAH1,TBC1D14,CLCN6,CDKN1B,CORO1A,F2R,TMEM9,TMBIM1,SNX8,SNX25,CLCN3,RAB7A,ATP6V0A1,CHMP2B,RAB1A,AP4E1,CHMP4A,ATP1A1,VPS26B,TAB2,CHMP4B,TICAM1,MAPK1,CHID1,AP2S1,GOLIM4,ANKRD13D,ANXA6,FLOT1,VPS45,TRAK1,ARF1,GGA2,RAB11A,SCYL2,TFRC,HLA-A,SPPL2A,CTSS,ST8SIA2,TPCN1,MYO5A,RHOA,SNX2,RFFL,KCNQ1,ZP3,SPPL2B,MAPK3,HLA-B,TMEM127,NUCB1,HGS,PDCD6,PRDX3,PML,CHMP7,RPS6KC1,VPS29 |
| 1.710e-04 | -8.67 | BECN1 (beclin 1) | protein interactions | 8678 | 87 | 28 | 17029 | 2761 |
TNFAIP3,MAPKAPK3,PRKDC,GOPC,DYNLL1,TUFM,MCL1,BRCA1,BCL2L1,WDR81,BECN1,CHAF1A,TSC1,SMC3,BIRC5,TAB2,ATG3,EXOC4,DAPK1,SLC27A4,BCL2,TCOF1,TP53BP2,WDR91,SEH1L,DDB1,CDKN2A,PTOV1 |
| 1.713e-04 | -8.67 | V$AP2_Q6_01 | MSigDB lists | V$AP2_Q6_01 | 252 | 60 | 17377 | 2626 |
DNMT3A,GGNBP2,PLXNC1,EYA1,FAM129A,FAM76A,DLGAP4,KLF13,PLAGL2,CTCF,B4GALT1,STMN1,POFUT1,VPS25,CDC73,PABPC4,BCAT2,FBRS,TFAP4,NRF1,KDM2A,ZNRF2,LRRC8D,RAB35,FAM89B,ANP32A,GLTP,CPSF4,ST8SIA2,PABPC1,NCOA2,TERF2,KDM3B,CELSR2,KLF10,ERF,C16orf72,CIC,LDB1,RDH10,CIRBP,PFKFB3,CADM1,ARID1A,PCGF1,EIF4G2,SYMPK,PICALM,TRIM28,TFEB,UBTF,PPP2R5A,TAB2,DGCR8,FASTK,OAZ2,ARAP1,PPP6R2,NR2F2,SMARCD1 |
| 1.716e-04 | -8.67 | snRNA transcription | biological process | GO:0009301 | 70 | 23 | 17256 | 2622 |
INTS2,POLR2I,RPRD1A,POLR2G,POLR2L,POLR2K,ELL2,INTS13,POLR2D,SNAPC4,SRRT,POLR2A,GTF2F1,CCNK,POLR2J,INTS7,INTS1,NABP1,NABP2,INTS12,ICE2,TAF6,RPRD1B |
| 1.716e-04 | -8.67 | snRNA transcription by RNA polymerase II | biological process | GO:0042795 | 70 | 23 | 17256 | 2622 |
INTS2,POLR2I,RPRD1A,POLR2G,POLR2L,POLR2K,ELL2,INTS13,POLR2D,SNAPC4,SRRT,POLR2A,GTF2F1,CCNK,POLR2J,INTS7,INTS1,NABP1,NABP2,INTS12,ICE2,TAF6,RPRD1B |
| 1.718e-04 | -8.67 | maturation of SSU-rRNA | biological process | GO:0030490 | 53 | 19 | 17256 | 2622 |
RPS24,BMS1,UTP3,TSR2,RRP36,RPSA,KRR1,KRI1,UTP25,UTP20,NOL11,LSM6,UTP18,RPS14,TBL3,RRS1,PDCD11,UTP4,BYSL |
| 1.720e-04 | -8.67 | GCM_TPT1 | MSigDB lists | GCM_TPT1 | 66 | 22 | 17377 | 2626 |
RPL29,RPS2,RPL35,RPLP2,NACA,RPS10,RPL6,RPL38,RPS24,RPL27A,RPS9,RPSA,RPL11,RPL23A,RPL32,RPS27A,RPL17,QARS,RPS14,RPLP1,RPL19,CFL1 |
| 1.720e-04 | -8.67 | GSE13738_RESTING_VS_TCR_ACTIVATED_CD4_TCELL_DN | MSigDB lists | GSE13738_RESTING_VS_TCR_ACTIVATED_CD4_TCELL_DN | 185 | 47 | 17377 | 2626 |
WSB2,SARNP,LYRM4,MRPL42,TM9SF4,SEC61G,PTTG1,TRAK1,BCL2L1,ZADH2,PPP1R16B,STAM,QSOX2,PARK7,TFRC,SEC11A,SLC31A1,IRF4,EIF2S2,TIMM23,IMPAD1,MBD2,SOCS6,SPTSSA,SYTL3,GM2A,FDFT1,PAQR6,COPS8,RDH10,NDUFA7,STYXL1,TXNL4A,CCT8,C19orf54,GNA12,ZNF282,SLCO4A1,BOLA3,PPP2R5A,UEVLD,PFDN4,DBI,COX5A,ZMIZ1,PGAM1,BYSL |
| 1.720e-04 | -8.67 | GSE43956_WT_VS_SGK1_KO_TH17_DIFFERENTIATED_CD4_TCELL_DN | MSigDB lists | GSE43956_WT_VS_SGK1_KO_TH17_DIFFERENTIATED_CD4_TCELL_DN | 185 | 47 | 17377 | 2626 |
TCF12,MRPL9,EIF3D,TRAK1,VPS45,AGFG1,MIEN1,PHC2,MDM2,UCHL5,ATP13A3,PTPN11,FOXN2,BRI3,FEM1B,CITED2,CGGBP1,IFRD1,CYFIP1,FOXK1,NEK7,MKI67,KCTD20,TOR1AIP2,GORASP2,GLO1,CBFA2T2,KLF6,ARF4,RHOB,PI4K2A,AMZ2,KPNA4,WAS,PDCD6,AHNAK,SYNCRIP,RAB24,HNRNPR,PTER,GADD45B,CAPN7,PRDX5,CAB39,RBMS1,SMAD4,SNX14 |
| 1.720e-04 | -8.67 | GSE3982_EOSINOPHIL_VS_EFF_MEMORY_CD4_TCELL_DN | MSigDB lists | GSE3982_EOSINOPHIL_VS_EFF_MEMORY_CD4_TCELL_DN | 185 | 47 | 17377 | 2626 |
GALK1,ZNF76,SH2D3A,NQO1,GNPDA1,CHD1L,NACA,HABP4,OLA1,BZW2,CD320,DDRGK1,MCTS1,CAPN2,LRRC8D,CD3EAP,ZNHIT6,SUCLG2,MDFIC,MAP3K14,FBL,PDIA6,SCYL3,ABCC5,NIPSNAP1,METTL1,EHMT1,ZBED5,LY6E,APPL1,RPA1,CAND1,RPL36,DTWD1,KIF2A,MAP3K4,DNAJC10,FBXO21,ETS2,PFDN4,STK38,ITGB1,GLG1,IARS2,COPS6,MRPL3,NMD3 |
| 1.720e-04 | -8.67 | GSE27786_BCELL_VS_NKCELL_DN | MSigDB lists | GSE27786_BCELL_VS_NKCELL_DN | 185 | 47 | 17377 | 2626 |
MIB2,RAB14,PRKAB1,PDCD6IP,AGTRAP,RAB11B,RAF1,SMC6,TBC1D13,IKBIP,MAP1LC3B,GOLM1,TNS3,RALB,LRRC8D,MTA1,IL6ST,ORAI1,GLTP,ABCD1,CYB5R1,UBE3B,MARCH2,CLN6,ACSL5,FTL,NCK1,RAB7A,NUDT4,OXR1,EMP3,RIT1,PRKRA,SH3GLB1,EPB41,MID1IP1,RBM47,OSBPL8,STAT6,DBI,NLRC5,CHMP4B,NCOA1,ZMIZ1,ARHGAP23,RTN3,SNX14 |
| 1.720e-04 | -8.67 | GSE20151_CTRL_VS_FUSOBACT_NUCLEATUM_NEUTROPHIL_DN | MSigDB lists | GSE20151_CTRL_VS_FUSOBACT_NUCLEATUM_NEUTROPHIL_DN | 185 | 47 | 17377 | 2626 |
CORO7,CDS2,ST13,ZCCHC8,FAM129A,YTHDC2,AGPAT1,TIA1,NDUFA4,POMP,NANS,UBE4A,RLF,GLRX3,STMN1,COMMD8,KTN1,CD59,PTEN,UCHL5,MBD2,PRC1,PIGG,ANXA5,SEPT11,SS18L1,CORO1A,CNN2,CYC1,SLC35A1,KDM3B,LARS,GUK1,POLR2G,APH1A,DHX29,NQO2,RPL6,RCOR1,USP22,PRMT2,TXNL4A,PEF1,ORMDL2,SEL1L,MDH1,ADNP2 |
| 1.720e-04 | -8.67 | GSE17721_LPS_VS_CPG_1H_BMDC_UP | MSigDB lists | GSE17721_LPS_VS_CPG_1H_BMDC_UP | 185 | 47 | 17377 | 2626 |
MMACHC,LZTR1,MRPL9,THOC1,DYNLL1,VPS45,RAB23,GTF3A,COMMD5,LCLAT1,PITHD1,RTKN,MLX,MED8,MCM5,FIZ1,SOCS6,MRPL34,AKR1B1,GPATCH1,PDCD2,TAF5L,POC5,PRPF19,CSTF1,ACSL5,PSPC1,PPP1R21,FBXO9,BMS1,CDC6,NFATC2IP,FANCE,SERP1,DHX15,SOCS7,CHCHD3,GOLGA7,SNAP23,PTER,RPLP1,TMEM101,COPS6,BRWD3,GCSH,TMEM33,PDF |
| 1.720e-04 | -8.67 | GSE1460_DP_THYMOCYTE_VS_NAIVE_CD4_TCELL_ADULT_BLOOD_DN | MSigDB lists | GSE1460_DP_THYMOCYTE_VS_NAIVE_CD4_TCELL_ADULT_BLOOD_DN | 185 | 47 | 17377 | 2626 |
CYTIP,CYLD,SH2D3A,ST13,RPLP2,HLA-E,ANKH,HABP4,AP3M2,CIB1,ASAH1,NENF,B4GALT4,PCYOX1L,CSDE1,TET3,GSTK1,IL6ST,CRAT,CRY2,BCL2,FBL,MVP,FAM171A1,TMBIM1,EEF1D,CYTH1,PBXIP1,CREG1,NET1,ZMYND11,RPL27A,STX16,SLC50A1,SERP1,SCARB2,PFDN5,TTC13,RPL32,WDR4,DTX4,LY75,FN3KRP,IMPDH1,PDXK,FAU,APOL2 |
| 1.731e-04 | -8.66 | MYBL2 (MYB proto-oncogene like 2) | protein interactions | 4605 | 54 | 20 | 17029 | 2761 |
NCOR2,LZTR1,EWSR1,FOXM1,E2F3,MYBL2,NUF2,SND1,CCNF,MAP1LC3B,LIN9,CCNA2,RBL1,HIPK2,E2F4,MAPK6,E2F1,RBBP4,CDK2,E2F2 |
| 1.731e-04 | -8.66 | TULP3 (tubby like protein 3) | protein interactions | 7289 | 54 | 20 | 17029 | 2761 |
USP7,EXOC3,PPP1R12A,FOXK1,PIP4K2C,JMJD6,THNSL1,GGPS1,PARN,MAPK3,MTMR3,RAD18,RALB,KBTBD7,PML,KANSL2,KLHL42,PDLIM5,ANKHD1,NUMB |
| 1.732e-04 | -8.66 | CDX1 (caudal type homeobox 1) | protein interactions | 1044 | 62 | 22 | 17029 | 2761 |
YTHDC1,ASH1L,DHX29,TWNK,GTPBP4,ZNF107,DHX8,SREK1,BMS1,UTP3,SRSF5,BUD13,ZNF121,ZFR,SRSF1,RBM23,UPF1,STRBP,KBTBD7,CABIN1,ANKHD1,CDK12 |
| 1.732e-04 | -8.66 | GSE37416_0H_VS_6H_F_TULARENSIS_LVS_NEUTROPHIL_UP | MSigDB lists | GSE37416_0H_VS_6H_F_TULARENSIS_LVS_NEUTROPHIL_UP | 180 | 46 | 17377 | 2626 |
FGFR1OP,TRERF1,NF1,PHB2,CXXC1,CSNK2A1,BTN3A1,GLUD1,ARGLU1,CHAC2,INO80E,USP48,SLC25A44,SLC12A9,RMI1,FAM8A1,ZNF92,ARL6IP6,NSFL1C,RNF135,MVP,SLC35A1,IMPA2,RNF169,CSNK1G3,FDFT1,ATP13A1,PTPN18,NASP,KIAA0040,MCL1,BICD2,NDUFB1,EIF3A,TSC1,DSN1,VPS26B,STK38,DBI,USP32,ATF6,CCDC125,YWHAH,HIPK3,CAPN1,PTOV1 |
| 1.732e-04 | -8.66 | GSE27786_ERYTHROBLAST_VS_NEUTROPHIL_DN | MSigDB lists | GSE27786_ERYTHROBLAST_VS_NEUTROPHIL_DN | 180 | 46 | 17377 | 2626 |
TRIM41,ST13,ZCCHC8,PHF23,MAGED1,KLC1,CDK13,AGFG1,TMED3,IKBIP,RAB11A,GIT2,ATPAF1,NDUFS4,EBP,CLUAP1,SAR1A,GOT2,ANP32A,ABCD1,TMEM8A,SLC35C2,ZNRD1,MCMBP,NAA35,ATP6V0D1,TRIM14,TIMM8B,ERLIN1,NLN,ABHD11,PRKRA,HERPUD2,RHOT1,PRPSAP1,BTBD1,TPD52L2,KPNA4,SMAD2,TMEM168,RAB24,PARG,CORO1C,CSNK1G1,ARAP1,SNAPIN |
| 1.732e-04 | -8.66 | GSE20500_CTRL_VS_RETINOIC_ACID_TREATED_CD4_TCELL_UP | MSigDB lists | GSE20500_CTRL_VS_RETINOIC_ACID_TREATED_CD4_TCELL_UP | 180 | 46 | 17377 | 2626 |
NAT9,MRPL9,FEZ2,PPCS,ADAM10,GNPDA1,TMEM109,ARFIP2,NENF,KIF2C,SNRPD3,DCUN1D4,RAB11A,PCYOX1L,COQ4,SLC38A10,COPS7B,SPTSSA,SLC35A1,HTRA2,SRPK2,LDHB,PGAP2,PTPN18,NSDHL,PRKDC,PPIE,HNRNPF,SLBP,CDC23,HAGH,DAP3,KEAP1,SYNCRIP,HINT1,PRDX3,TIMM17A,ARNTL,FN3KRP,MLYCD,NUP62,SNRPG,E2F2,NGLY1,AP2S1,TUBB |
| 1.737e-04 | -8.66 | GSE6269_FLU_VS_STREP_PNEUMO_INF_PBMC_UP | MSigDB lists | GSE6269_FLU_VS_STREP_PNEUMO_INF_PBMC_UP | 160 | 42 | 17377 | 2626 |
PARP12,MRPL42,DCAF15,NF1,HLA-E,HMGXB3,SMARCA4,HLA-A,RFWD3,FANCL,GART,PPIG,NAA35,TRIM14,MLEC,MKLN1,DDX24,DHX29,ILF3,WDHD1,NFATC2IP,IL12RB1,LY6E,PSMB9,PDHX,MARK2,ISG15,AKAP1,HLA-B,RAD51C,SYNCRIP,RBM25,BRD2,MAP4,STAT1,PML,GLG1,COX8A,NUP62,PURA,COIL,IFI16 |
| 1.740e-04 | -8.66 | PAK1IP1 (PAK1 interacting protein 1) | protein interactions | 55003 | 28 | 13 | 17029 | 2761 |
NOL12,PPAN,NIFK,MDM2,RRP15,DGCR8,RBM34,CUL3,SMURF1,ZC3H3,RBM4,IFI16,RPL11 |
| 1.740e-04 | -8.66 | SAP25 (Sin3A associated protein 25) | protein interactions | 100316904 | 28 | 13 | 17029 | 2761 |
SAP130,BRMS1,PRKDC,PML,OGT,KPNA2,TTLL12,LPCAT1,ZC3HAV1,CDKN2A,SEH1L,HDAC2,SAP30 |
| 1.743e-04 | -8.65 | REACTOME_SIGNALING_BY_THE_B_CELL_RECEPTOR_BCR | MSigDB lists | REACTOME_SIGNALING_BY_THE_B_CELL_RECEPTOR_BCR | 121 | 34 | 17377 | 2626 |
TSC2,CUL1,AKT1S1,PSMD9,LYN,FOXO3,VAV1,CALM2,PSMD2,MDM2,PSMA6,PSMD1,SHC1,PTEN,CDKN1B,ORAI1,CREB1,MLST8,PDPK1,NRAS,NCK1,PSMA8,AKT2,PSMB7,PSMA1,KRAS,PSMB9,PSMB3,PSMC4,RPS27A,PSMD3,PSMD8,HRAS,PSMC1 |
| 1.743e-04 | -8.65 | GSE6259_DEC205_POS_DC_VS_CD8_TCELL_UP | MSigDB lists | GSE6259_DEC205_POS_DC_VS_CD8_TCELL_UP | 165 | 43 | 17377 | 2626 |
OTUD5,RHOG,TOMM20,UGP2,RPLP2,DHPS,TCF3,ACTR3,SCYL1,MRPS26,CERK,GLUD1,IRF3,RGS2,PARK7,ATG3,SSBP3,AP1M1,CORO1A,METTL9,GNAI2,LYPLA2,NIPSNAP1,SIGMAR1,DRAP1,TUFM,VDAC2,ANAPC2,PDE3B,PSMB9,SERP1,EIF3H,PLEKHF2,NECAP2,CAT,MID1IP1,GPS2,CSK,ARNTL,COX7A2L,ITGB1,AP2S1,DCAF5 |
| 1.744e-04 | -8.65 | BAKKER_FOXO3_TARGETS_DN | MSigDB lists | BAKKER_FOXO3_TARGETS_DN | 170 | 44 | 17377 | 2626 |
SYS1,MUT,MRPS26,FAM136A,SLC20A1,SMC3,MEX3C,MED10,SRSF4,LTN1,PCYT2,RNASEH2A,TNRC18,STRAP,COPS8,ZNF524,DEAF1,HMGN1,SEC61B,GUK1,RNASEH2C,MAPKAPK3,MKI67,PSMA1,PFKFB3,RCOR1,DCLRE1C,WBP1,GFER,SNRPA,GLOD4,ANKRD10,ANKZF1,LEMD2,SLC19A1,TULP3,WDR4,COX8A,SEL1L,YY1,ARHGAP23,CDK2,TUBB,N4BP2L2 |
| 1.759e-04 | -8.65 | human chr11q13.1 | chromosome location | human chr11q13.1 | 115 | 26 | 26185 | 2809 |
POLA2,SART1,RNASEH2C,DRAP1,SCYL1,SNX15,SYVN1,MEN1,FKBP2,MARK2,FERMT3,SAC3D1,SF3B2,GPR137,SPINDOC,PRDX5,BANF1,CDCA5,COX8A,FAM89B,FAU,FRMD8,RTN3,CFL1,SSSCA1,CAPN1 |
| 1.759e-04 | -8.65 | alternative mRNA splicing, via spliceosome | biological process | GO:0000380 | 16 | 9 | 17256 | 2622 |
RBM17,SRSF6,DHX9,PQBP1,DDX5,CDK13,HNRNPM,SRSF1,DDX17 |
| 1.763e-04 | -8.64 | viral translation | biological process | GO:0019081 | 13 | 8 | 17256 | 2622 |
EIF3L,EIF3D,EIF2D,EIF2AK4,EIF3G,EIF3A,PCBP2,MCTS1 |
| 1.764e-04 | -8.64 | DUTERTRE_ESTRADIOL_RESPONSE_6HR_UP | MSigDB lists | DUTERTRE_ESTRADIOL_RESPONSE_6HR_UP | 221 | 54 | 17377 | 2626 |
POLA2,MCM10,NOP2,ANKH,SLC29A1,AP1B1,DTL,LYAR,TFAP4,GART,PCNA,SLC1A4,MCM5,XRCC2,ADCY9,BCL2,OSTF1,SLC26A2,POLR1B,LDLRAD3,MYBL1,TIPARP,SEH1L,PPIF,PPAN,ABHD2,RFC3,SEPT9,CELSR2,AMD1,WDHD1,CDC6,BRCA1,MCM2,ASB13,MACF1,CHAF1A,PRIM1,AKAP1,RPL32,RBL1,NIP7,ZNF367,WDR4,E2F1,SLC16A1,MBOAT1,XRCC3,FKBP5,SCARB1,WDR76,RRS1,PDCD11,LRP8 |
| 1.772e-04 | -8.64 | cell-substrate junction | cellular component | GO:0030055 | 405 | 87 | 18223 | 2701 |
RHOG,PDCD6IP,ADD1,RPLP2,ADAM10,RAC1,ACTR3,ZFYVE21,MYH9,CPNE3,GIT2,GNB2,DST,RAB21,CDC42,DNM2,SENP1,CFL1,PCBP2,CHP1,LAP3,RPL38,EZR,ERBIN,STX16,RPS9,ALKBH6,AHNAK,JAK1,RPS14,CORO1C,LIMK1,ITGB1,RPLP1,ADAM9,ATP6V0C,ACTB,MAPK1,CAPN1,NUMB,PPIB,RPS15,RPS2,PPP1R12A,ANXA6,FLOT1,LAMTOR3,KIF23,SLC4A2,ARF1,NCKAP1,ITGB5,PIP5K1C,CAPN2,CD59,TNS3,FGFR3,VASP,ARPC5,ANXA5,ARHGEF2,RPL19,CNN2,PABPC1,PDPK1,CYFIP1,DCAF6,ADAM17,RHOA,CSRP1,FOCAD,RPL6,RPL8,RPS10,KRAS,PLEC,MAP2K2,RHOB,MAPK3,HSPA1B,CAT,GNA12,SCARB2,PDLIM1,SNAP23,YWHAZ,CD81 |
| 1.774e-04 | -8.64 | protein folding | biological process | GO:0006457 | 251 | 60 | 17256 | 2622 |
PPIB,DNAJC2,HSPH1,ST13,PRKCSH,DNAJB2,UBXN1,TMX4,MOGS,TMX3,DNAJC24,ZFYVE21,CSNK2A1,DNAJB1,FKBP2,QSOX2,GNB2,FKBP1A,CWC27,PPIG,PPIL2,RAD23B,RP2,TTC4,PTGES3,PIKFYVE,LMAN1,GNAI2,PDIA6,TMX1,PDCL3,NUDC,CDC37,PPIF,RPAP3,CCT2,MLEC,ERO1A,PPIE,DNAJA1,FKBP3,CCT8,BBS12,HSPA1B,DERL1,DNAJC10,PFDN5,HSPA4,HSPBP1,LTBP4,PFDN4,PDRG1,RPS27A,SIL1,FKBP5,ATF6,RUVBL2,CLU,NGLY1,PSMC1 |
| 1.779e-04 | -8.63 | cell cycle DNA replication | biological process | GO:0044786 | 41 | 16 | 17256 | 2622 |
GINS1,POLA2,RFC3,PRIM2,CDT1,WDR18,SLBP,RFC2,PRIM1,RPA1,RPA2,UPF1,PCNA,POLE,ZNF830,ORC3 |
| 1.780e-04 | -8.63 | PSMB1 (proteasome subunit beta 1) | protein interactions | 5689 | 127 | 37 | 17029 | 2761 |
UNK,MAPRE1,CYLD,RBM8A,POMP,NOTCH2,PSEN1,HAUS2,RAD23A,HNRNPA2B1,PSMD2,PSMD1,CLIC4,PSMA6,UCHL5,FBXO7,CDKN1B,PLK1,EXOSC6,MAPRE2,PSMA8,VHL,PSMB7,PSMA1,PSMG1,UBE2V1,SYVN1,UBE4B,MCM2,PSMB9,PSMB3,PSMC4,FBXO28,PSMD3,PSMD8,ASNA1,PSMC1 |
| 1.790e-04 | -8.63 | CCNA2 (cyclin A2) | protein interactions | 890 | 118 | 35 | 17029 | 2761 |
CDT1,CUL1,ORC1,SRRT,RAD23A,CDK5,RB1,PCNA,PSMA6,CCNA2,PRC1,CDKN1B,ARID4A,HELB,MYBL2,E2F3,SLBP,CDC6,KRAS,PKMYT1,BRCA1,FXR1,RPA1,UBTF,PDCD6,CDC27,RBL1,E2F4,UHRF2,E2F1,COPS6,TAF6,CDK2,HDAC2,ANAPC4 |
| 1.805e-04 | -8.62 | PECE_MAMMARY_STEM_CELL_DN | MSigDB lists | PECE_MAMMARY_STEM_CELL_DN | 126 | 35 | 17377 | 2626 |
UBL3,PNISR,ZCCHC9,ANKH,TRIO,TIA1,GLUD1,MAP1LC3B,SLC25A43,APP,VMP1,ZKSCAN1,TIMM23,IMPAD1,BTF3L4,ARHGEF2,KIFAP3,FGFR1OP2,CDC5L,NASP,DENND4C,DCTD,ARMC8,RAB2B,XRCC5,ANKRD10,DERL1,ZNF862,CDC16,PCM1,JAK1,ITGB1,ANP32E,SRSF3,RUFY3 |
| 1.806e-04 | -8.62 | Cytoplasmic Ribosomal Proteins | WikiPathways | WP477 | 90 | 28 | 5312 | 837 |
RPL29,RPS15,RPS2,RPL35,RPLP2,RPS6KA1,RPL8,RPL38,RPL6,RPS10,RPS24,RPL15,RPL27A,RPS9,MRPL19,RPSA,RPL11,RPL36,RPL23A,RPL37,RPL32,RPL17,RPS27A,RPS14,RPLP1,RPL19,FAU,RPS26 |
| 1.817e-04 | -8.61 | MTHFD1 (methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1) | protein interactions | 4522 | 83 | 27 | 17029 | 2761 |
ABCF2,ACSL3,CUL3,BRCA1,ADRB2,MCM2,TMEM165,EIF3G,CDC73,PARK7,MAT2A,RPA1,PAPOLA,RPA2,MEX3C,RPL32,SAR1A,ZNF746,IARS2,CRY2,FUS,ALDH18A1,SNRNP70,CDK2,CD81,PFKP,PRPF19 |
| 1.817e-04 | -8.61 | UBA5 (ubiquitin like modifier activating enzyme 5) | protein interactions | 79876 | 83 | 27 | 17029 | 2761 |
CYTH1,TP53RK,PDCD6IP,LAP3,UFC1,MOGS,SND1,MCM2,DDX39A,CCT8,TARS,COPB2,EIF3A,USP5,DDX17,PA2G4,PSMD2,MZT2A,ATP6V1D,PRDX3,ACOX1,UBA5,SH3GLB2,NSFL1C,ANP32E,LTA4H,CDC5L |
| 1.817e-04 | -8.61 | NAGK (N-acetylglucosamine kinase) | protein interactions | 55577 | 83 | 27 | 17029 | 2761 |
BCCIP,TCF12,FGFR1OP,GCLM,GNPNAT1,WDR1,LDHA,LSM8,WDR82,LACTB2,PKM,DDX39A,PATL1,ARID1B,C2orf68,CDKN2C,MTHFD2,SMAD2,MCM5,PPIL2,RBM3,CNN2,WIPI2,GNAI2,TERF1,C2CD5,SRPK2 |
| 1.818e-04 | -8.61 | ZHONG_SECRETOME_OF_LUNG_CANCER_AND_MACROPHAGE | MSigDB lists | ZHONG_SECRETOME_OF_LUNG_CANCER_AND_MACROPHAGE | 75 | 24 | 17377 | 2626 |
KCTD7,PPIB,CYTIP,TIMP2,AGRN,CREG1,MDH2,PSMB7,LDHA,APP,PRDX1,CHAF1A,PSMA6,GOT2,DUT,CANT1,MDH1,CTSA,YWHAZ,ACTB,CDC25B,CLU,TALDO1,CD81 |
| 1.818e-04 | -8.61 | SHAFFER_IRF4_TARGETS_IN_ACTIVATED_B_LYMPHOCYTE | MSigDB lists | SHAFFER_IRF4_TARGETS_IN_ACTIVATED_B_LYMPHOCYTE | 75 | 24 | 17377 | 2626 |
CCNC,TIMP2,GNPDA1,ELL2,UCK2,LDHA,KRAS,CYCS,VDAC1,KTN1,CFLAR,IRF4,SLC31A1,GART,EIF2S2,UAP1,GOLGA7,OSBPL8,GRSF1,SEPT11,AHCY,BCL2,TAGLN2,FDFT1 |
| 1.827e-04 | -8.61 | myeloid cell activation involved in immune response | biological process | GO:0002275 | 512 | 108 | 17256 | 2622 |
RHOG,ADA2,KARS,RAB14,ADAM10,DYNLL1,RAC1,HEXB,NIT2,NHLRC3,GYG1,MAPK14,LYN,KCMF1,CMTM6,CPNE3,PA2G4,RAP1A,PSMD1,AP1M1,BRI3,TMBIM1,GM2A,KCNAB2,ENPP4,CPNE1,CCT2,TIMP2,NRAS,RAB7A,ARHGAP45,PPIE,CYSTM1,PSMB7,ATP6V0A1,RAB5B,TOLLIP,ALDH3B1,DSN1,AGPAT2,DDOST,SURF4,RAB24,PSMD3,CAB39,CANT1,ATP6V0C,TICAM1,ROCK1,PDXK,LTA4H,MAPK1,CAPN1,TUBB,SVIP,MIF,DNAJC5,GMFG,MANBA,PDAP1,LAMTOR3,B4GALT1,ASAH1,CDK13,MAN2B1,RAB6A,PSEN1,TMEM179B,GNS,CD59,PSMD2,CTSS,ARPC5,HUWE1,OSTF1,CNN2,MVP,LPCAT1,SPTAN1,CYFIP1,FTL,MLEC,RHOA,CREG1,C1orf35,HEBP2,PKM,ARMC8,CCT8,NEU1,HSPA1B,PI4K2A,CAND1,XRCC5,CAT,RAB18,ATP6V1D,MAGT1,GOLGA7,SNAP29,SNAP23,ACLY,PGRMC1,IMPDH1,CTSA,PSAP,GPI,PGAM1 |
| 1.840e-04 | -8.60 | benign_melanocytic_nevus | COSMIC cancer mutations | benign_melanocytic_nevus | 34 | 14 | 17385 | 2587 |
KIF5B,PWWP2A,FGFR3,NRAS,ZCCHC8,STK11,KRAS,ERC1,HRAS,LMNA,HLA-A,CDKN2A,MYO5A,DCTN1 |
| 1.842e-04 | -8.60 | POC1A (POC1 centriolar protein A) | protein interactions | 25886 | 96 | 30 | 17029 | 2761 |
RPAP3,CCT2,SKA3,MAPRE2,LUZP1,R3HCC1L,CAMSAP1,RRM2,HAUS4,MAP7D1,ATG2B,COMMD4,CCT8,TAF2,PFDN5,DAP3,PFDN4,DNAAF2,PELO,GTSE1,SIL1,CORO1A,BTF3,ECD,AHCYL1,FGFR1OP2,POC5,PDCL3,SSSCA1,NUDC |
| 1.842e-04 | -8.60 | HIST1H2BA (histone cluster 1 H2B family member a) | protein interactions | 255626 | 96 | 30 | 17029 | 2761 |
TRIM41,COX15,H2AFZ,SUZ12,CHD1L,TEX10,MIER1,C16orf87,EHMT1,MEF2A,MCM2,APP,HMG20A,MEAF6,SUPT16H,NAP1L1,TONSL,MCM5,JAZF1,PHF14,PPM1G,KBTBD7,H2AFY,ANP32E,RUVBL2,NAP1L4,CREB1,CD81,HDAC2,SSRP1 |
| 1.844e-04 | -8.60 | skin-face-other-atypical_Spitzoid_tumour | COSMIC cancer mutations | skin-face-other-atypical_Spitzoid_tumour | 23 | 11 | 17385 | 2587 |
KIF5B,PWWP2A,NRAS,ZCCHC8,HRAS,ERC1,HLA-A,CDKN2A,MYO5A,LMNA,DCTN1 |
| 1.844e-04 | -8.60 | skin-upper_leg-other-atypical_Spitzoid_tumour | COSMIC cancer mutations | skin-upper_leg-other-atypical_Spitzoid_tumour | 23 | 11 | 17385 | 2587 |
KIF5B,PWWP2A,NRAS,ZCCHC8,HRAS,ERC1,HLA-A,CDKN2A,MYO5A,LMNA,DCTN1 |
| 1.844e-04 | -8.60 | skin-scalp-benign_melanocytic_nevus-Spitz | COSMIC cancer mutations | skin-scalp-benign_melanocytic_nevus-Spitz | 23 | 11 | 17385 | 2587 |
KIF5B,PWWP2A,NRAS,ZCCHC8,HRAS,ERC1,HLA-A,CDKN2A,MYO5A,LMNA,DCTN1 |
| 1.844e-04 | -8.60 | skin-arm-other-atypical_Spitzoid_tumour | COSMIC cancer mutations | skin-arm-other-atypical_Spitzoid_tumour | 23 | 11 | 17385 | 2587 |
KIF5B,PWWP2A,NRAS,ZCCHC8,HRAS,ERC1,HLA-A,CDKN2A,MYO5A,LMNA,DCTN1 |
| 1.844e-04 | -8.60 | skin-lower_leg-other-atypical_Spitzoid_tumour | COSMIC cancer mutations | skin-lower_leg-other-atypical_Spitzoid_tumour | 23 | 11 | 17385 | 2587 |
KIF5B,PWWP2A,NRAS,ZCCHC8,HRAS,ERC1,HLA-A,CDKN2A,MYO5A,LMNA,DCTN1 |
| 1.844e-04 | -8.60 | atypical_Spitzoid_tumour | COSMIC cancer mutations | atypical_Spitzoid_tumour | 23 | 11 | 17385 | 2587 |
KIF5B,PWWP2A,NRAS,ZCCHC8,HRAS,ERC1,HLA-A,CDKN2A,MYO5A,LMNA,DCTN1 |
| 1.844e-04 | -8.60 | soft_tissue-fibrous_tissue_and_uncertain_origin-fibrosarcoma | COSMIC cancer mutations | soft_tissue-fibrous_tissue_and_uncertain_origin-fibrosarcoma | 23 | 11 | 17385 | 2587 |
CDKN2C,NRAS,NF1,SF3B1,ETV6,RAC1,STK11,KRAS,FUS,HRAS,CDKN2A |
| 1.857e-04 | -8.59 | regulation of protein metabolic process | biological process | GO:0051246 | 2752 | 481 | 17256 | 2622 |
FGFR1OP,TXN,TSC2,MAP3K7CL,XIAP,YTHDF3,CCNL2,CCNB1,UBE2I,EIF1B,PPP1R16B,RBM4,RIC1,PARK7,FBXO22,EEF2K,CALM2,CDK5,CDKN2C,PA2G4,PSMD1,FIZ1,RAD23B,CRY2,FNIP2,MAST2,CDC25B,PLCL2,TIPARP,DNMT1,SENP1,MLST8,BAK1,PLK3,AATF,AKT2,PBK,MRNIP,TOPORS,DCUN1D5,EIF3A,IWS1,MAP3K4,BRMS1,HHEX,MKNK1,TMED10,RPS27A,RPS14,LIMK1,AXIN1,PRDX5,OGT,ARRB2,ZNF598,OAZ1,HDAC2,PDCD4,SVIP,PPIB,HSPH1,CLSPN,GMFG,GGA1,PHF23,GADD45G,PRKAA1,DHX9,CYCS,EIF2AK4,NOTCH2,PSEN1,METTL3,VPS25,WDR48,CNOT3,CFLAR,DDRGK1,NDUFS4,CD59,TFAP4,FKBP1A,MEX3C,FBXO7,PPP4R1,DAPK1,MYDGF,MVP,GNAI2,LPCAT1,PABPC1,NSUN4,PPP6R1,SOCS5,EIF5A,CYFIP1,RB1CC1,MAPKAPK3,ZMYND11,GTPBP4,ITM2A,ADRB2,PTTG1IP,CYFIP2,FXR1,KDM3A,EIF4H,MAP2K2,FAS,XRCC5,DERL1,EPRS,HSPBP1,FNTA,GOLGA2,NSF,DUSP3,CSK,QARS,FAM83D,CEBPG,CABIN1,TCOF1,PPP6R3,MAP3K5,RNF14,RNF139,ALS2,CDKN2A,KARS,PPP1R37,SARNP,ATXN3,GGNBP2,RPS6KA1,CAST,RAF1,EIF3D,PTTG1,MAGED1,RAC1,TPX2,MYH9,CREBL2,DAZAP2,PRKACA,ANKIB1,APP,PAIP2,TERF2IP,CRKL,APLP2,SHC1,RALB,MTA1,UCHL5,DDA1,ADCY9,SOCS6,MRPS27,NSFL1C,CDKN1B,RNF19A,MAVS,CLN6,GPD1L,CDK12,PDCL3,ADCY7,ANKLE2,SHOC2,PSRC1,BRD4,CDC123,EID1,KAT7,MAP4K4,TAOK1,WBP2,RPL38,POLR2D,CUL3,CIRBP,ELP4,CDCA2,PKMYT1,DNAJA1,RAB1A,PSMB9,SERP1,SOCS7,PPP2CA,EIF3K,PPP2R5A,CORO1C,HIPK2,RPLP1,TICAM1,TRIM32,PPP5C,LRP8,CSNK1D,USP13,RPS2,MECP2,ZFP91,HABP4,FLOT1,SECISBP2,AKT1S1,BLM,HMG20A,FOXO3,MAD2L2,WWP2,PPP1R3B,CCNK,PSMD2,PDCD10,PTEN,PPP1R8,PTPN11,AXIN2,LTN1,FEM1B,CNOT6L,MAP3K14,PDPK1,ZFP64,KAT2A,LONRF3,TNFAIP3,JTB,ILF3,MARK2,PICALM,FADD,PRDX1,SH3BP5,GNA12,KEAP1,HGS,LTBP4,GPS2,PRDX3,PARG,OAZ2,LRPPRC,PML,KHSRP,PPP1R11,PSAP,WDR91,CD81,PARP10,IGBP1,CPEB2,PURA,FAF1,DDB1,ZBED3,CCNC,NF1,KMT2E,PPP1R15B,FAM129A,RBM8A,ENSA,DNAJC24,CSNK2A1,NENF,SIRT2,UBQLN2,S1PR2,MAPK14,BIRC2,FANCI,ZER1,PRNP,RAP1A,EIF4A3,IL6ST,METTL14,PIK3R2,NOC2L,EIF5,MTPN,CDC37,RYBP,PLK1,COPS8,RBX1,NCK1,GMFB,EZR,CDC6,UBE2V1,LRP5,BRCA1,SOX4,ODC1,PAF1,GEMIN5,EIF4ENIF1,SOCS4,CAB39,ADAM9,STK11,CHEK2,CLU,ROCK1,DVL1,CLN3,PSMC1,PPP1R2,PPP1R12A,GORASP1,PHB2,DNAJB2,UBXN1,NKD2,LAMTOR3,CIB1,TIA1,PM20D2,RGS2,CNOT11,RHBDD1,APOPT1,DTL,RB1,ARL6IP1,ZNF335,CTR9,BCL2,MDFIC,RBM3,GLE1,ATP5IF1,OXR1,LDB1,GBA,KRAS,EIF2AK1,MAP4K3,RTF1,EIF2A,EIF4G2,DAPK3,ISG15,MASTL,PSMC4,TSC1,MBIP,SYNCRIP,NSMF,SIAH2,NUP62,CTSA,RUVBL2,EHD4,SNRNP70,TOB1,RNF114,BCCIP,USP7,ASH1L,TRAF7,IFI27L1,FOXM1,SUMO2,IRF3,LYN,DUSP22,BCAP31,PAIP1,RPL11,RAD23A,USP5,UBXN2A,MDM2,TNFAIP8,PIN1,KIF14,PPME1,AKAP8,PARL,PDCD2,TARDBP,CHTOP,F2R,STRAP,ABI1,CTDSP2,HTRA2,DVL2,CHP1,SNX25,UBQLN4,TIMP2,BIRC3,POLR2G,RAB7A,BTG2,EDEM2,PEF1,TOLLIP,RPS9,EIF3H,BTBD1,DNAJC10,IDE,TAB2,HNRNPR,SCAP,UBXN2B,PSMD3,STK38,TIMM17A,GADD45B,ARNTL,PLGRKT,SMURF1,MAPK1,SMAD4,PPP2R2D,PARD3,BCL2L12,MIF,UNK,MIF4GD,TRIP12,DAP,AGO2,PAWR,DCUN1D4,CSNK1A1,FBXO5,PTPN2,FASTKD3,FGFR3,IRF4,TANK,DUS2,H2AFY,ARHGEF2,BRD7,ATG13,LDLRAD3,STAT3,TGFB1,SAMD4B,COA3,TELO2,PPP1R9B,ADAM17,RHOA,PRKDC,PRKAR1B,RFFL,MEN1,SYMPK,MAPK3,HSPA1B,CNOT9,LEMD2,PDCD6,NEK1,UPF1,PLAA,BIRC5,TWSG1,OSBPL8,GLG1,KMT2B,PKD2,NR2F2,UBE2C,HRAS,HIPK3,IFI16 |
| 1.860e-04 | -8.59 | MORF_SART1 | MSigDB lists | MORF_SART1 | 62 | 21 | 17377 | 2626 |
SART1,MRPL9,RPLP2,SUMO2,NACA,RNPS1,RPL6,COX4I1,USP22,UBE2I,EIF4G2,DDX39A,PSMB3,RPS27A,HUWE1,YWHAZ,IDH3B,FAU,STRAP,EEF1D,PCBP2 |
| 1.860e-04 | -8.59 | GNF2_ST13 | MSigDB lists | GNF2_ST13 | 62 | 21 | 17377 | 2626 |
EIF3L,ST13,EIF3D,NACA,RPL6,RPL38,RPL8,RPL15,RPS24,SNRPD3,RPSA,EIF3H,RPL37,NSA2,RPL32,RPL17,RBMX,RPL19,SRSF3,BTF3,FBL |
| 1.868e-04 | -8.59 | cell-substrate adherens junction | cellular component | GO:0005924 | 400 | 86 | 18223 | 2701 |
RHOG,PDCD6IP,ADD1,RPLP2,ADAM10,RAC1,ACTR3,ZFYVE21,MYH9,CPNE3,GIT2,GNB2,DST,RAB21,CDC42,DNM2,SENP1,CFL1,PCBP2,CHP1,LAP3,RPL38,EZR,STX16,RPS9,ALKBH6,AHNAK,JAK1,RPS14,CORO1C,LIMK1,ITGB1,RPLP1,ADAM9,ATP6V0C,ACTB,MAPK1,CAPN1,NUMB,PPIB,RPS15,RPS2,PPP1R12A,ANXA6,FLOT1,LAMTOR3,KIF23,SLC4A2,ARF1,NCKAP1,ITGB5,PIP5K1C,CAPN2,CD59,TNS3,FGFR3,VASP,ARPC5,ANXA5,ARHGEF2,RPL19,CNN2,PABPC1,PDPK1,CYFIP1,DCAF6,RHOA,ADAM17,CSRP1,FOCAD,RPL6,RPL8,RPS10,KRAS,PLEC,MAP2K2,RHOB,MAPK3,HSPA1B,CAT,GNA12,SCARB2,PDLIM1,SNAP23,YWHAZ,CD81 |
| 1.868e-04 | -8.59 | IL-5 Signaling Pathway | WikiPathways | WP127 | 40 | 16 | 5312 | 837 |
JAK1,SHC1,RAF1,RPS6KA1,PIK3R2,PTPN11,STAT1,BCL2,KRAS,ELK1,STAT3,MAPK1,LYN,FOXO3,MAP2K2,MAPK3 |
| 1.872e-04 | -8.58 | SMAD1 (SMAD family member 1) | protein interactions | 4086 | 169 | 46 | 17029 | 2761 |
MBD1,RHOG,ZNF76,ANKRD27,NAT9,EWSR1,SF3B1,PIGQ,UBXN1,UBE2Z,NOTCH2,EIF2AK4,FOXO3,TTF1,APP,LMNA,PSMD1,GMEB1,AKR1B1,SS18L1,SMARCE1,STAT3,PREB,KAT2A,BTG2,CAMSAP1,ERBIN,MEN1,ZDHHC3,RAB2B,HGS,SMAD2,RPS27A,HIPK2,MED15,DVL1,YY1,SNRNP70,SMAD1,MAPK1,SMURF1,SMAD4,TOB1,OAZ1,PARD3,RHEBL1 |
| 1.875e-04 | -8.58 | FLNA (filamin A) | protein interactions | 2316 | 301 | 73 | 17029 | 2761 |
CYLD,LUZP1,ACTR3,RAC1,MYH9,IKBIP,CCNB1,MAPK14,GNB2,CDC42,PPME1,AP2B1,TRA2B,CRY2,CLTB,PCBP2,CFL1,PPP1R18,VHL,CUL3,BRCA1,MCM2,ANLN,CORO1C,MYO18A,ITGB1,CHMP4B,ACTB,DMWD,ARRB2,SMURF1,NMD3,DYNC1LI2,OTUD5,MAPRE1,PPP1R12A,TRIO,FLOT1,DNAAF5,ITGB5,PSEN1,CDC73,LMNA,CD59,RPA2,MCM5,BANF1,CAPZA1,MCPH1,MYO5A,CAMK2G,SPTAN1,SRSF11,STAU1,PPP1R9B,RHOA,WDR1,MYBL2,PLEC,CAPZA2,ADRB2,DAPK3,ISG15,RPA1,GNAS,PFDN5,INF2,UAP1,TXNDC16,PFDN4,HMGB2,CDK2,CD81 |
| 1.876e-04 | -8.58 | TP53 Regulates Metabolic Genes | REACTOME pathways | R-HSA-5628897 | 82 | 27 | 10287 | 1696 |
COX5B,PRKAB1,TXN,TSC2,AKT2,PRKAA1,AGO2,LAMTOR3,RRAGC,NDUFA4,COX4I1,CYCS,RHEB,PRDX1,TSC1,TIGAR,PTEN,PRDX5,LAMTOR4,COX7A2L,LRPPRC,COX8A,COX5A,YWHAZ,GPI,YWHAH,MLST8 |
| 1.879e-04 | -8.58 | B14GALTRFASE | prints domains | PR02050 | 7 | 5 | 4652 | 473 |
B4GALT1,B4GALT4,B4GALT3,B4GALT5,B4GALT2 |
| 1.880e-04 | -8.58 | regulation of pH | biological process | GO:0006885 | 102 | 30 | 17256 | 2622 |
CLCN3,PPT1,TM9SF4,RAB7A,GPR89A,SLC26A6,ATP6V0A1,SLC4A2,ATP5F1B,ATP6V1B2,TMEM165,MAPK3,ATP6V0B,PDK2,ATP6V1D,CLIC4,ATP6V0A2,BCL2,ATP6V0C,SLC26A2,ATP6V1C1,CLN3,CLN6,MAPK1,ATP6V0D1,ATP6V0E1,GPR89B,SNAPIN,ATP6V1G1,CHP1 |
| 1.908e-04 | -8.56 | BAH | prosite domains | PS51038 | 11 | 7 | 12060 | 1670 |
ORC1,PBRM1,ASH1L,TNRC18,DNMT1,MTA2,MTA1 |
| 1.908e-04 | -8.56 | ZF_CXXC | prosite domains | PS51058 | 11 | 7 | 12060 | 1670 |
KMT2B,MBD1,CXXC4,KDM2A,FBXL19,DNMT1,CXXC1 |
| 1.908e-04 | -8.56 | MBD | prosite domains | PS50982 | 11 | 7 | 12060 | 1670 |
MBD1,MBD6,MBD3,BAZ2A,MECP2,MBD2,MBD4 |
| 1.916e-04 | -8.56 | ATPase complex | cellular component | GO:1904949 | 95 | 28 | 18223 | 2701 |
PHF10,MTA2,SUZ12,ABCF2,CSNK2A1,SMARCA4,ARID1A,PBRM1,INO80E,MBD3,APPL1,ARID1B,YY1AP1,USF1,RB1,ATP1A1,CHD3,UCHL5,APPL2,ANP32E,SS18L1,RUVBL2,YY1,RBBP4,SMARCE1,GM2A,HDAC2,SMARCD1 |
| 1.917e-04 | -8.56 | astrocytoma | COSMIC cancer mutations | astrocytoma | 38 | 15 | 17385 | 2587 |
CDKN2C,FGFR3,NRAS,NF1,PTEN,VHL,CIC,SF3B1,GOPC,PTPN11,KRAS,H3F3A,HRAS,CDKN2A,FUBP1 |
| 1.923e-04 | -8.56 | RTRAF (RNA transcription, translation and transport factor) | protein interactions | 51637 | 79 | 26 | 17029 | 2761 |
COX15,THOC1,PRKDC,TCF3,DHX9,CUL3,CUL1,PSMG1,MCM2,C2orf49,RFC2,KDM3A,ABCF1,PICALM,MATR3,FKBP3,RPA1,CAND1,RPA2,AHNAK,SYNCRIP,HUWE1,RTCB,DDX5,FUS,ECPAS |
| 1.923e-04 | -8.56 | HADHA (hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha) | protein interactions | 3030 | 79 | 26 | 17029 | 2761 |
ABCF2,SDC2,RTF1,NFATC2,CAPZA2,TOMM40,MCM2,VDAC1,MAP1LC3B,CDC73,PARK7,ZFR,CAND1,PTPN2,GRSF1,PIN1,DDA1,ZNF746,HADHB,ATXN2L,MRPL40,PLOD3,CDK2,ATF2,NIPSNAP2,PPP6R1 |
| 1.923e-04 | -8.56 | ZYX (zyxin) | protein interactions | 7791 | 105 | 32 | 17029 | 2761 |
CYLD,UGP2,UFC1,PPP3CB,CNTROB,ATP6V1B2,RGS2,PAPOLA,VAV1,VASP,GART,SEC24C,AHSA1,RAD23B,CNN2,AHCYL1,TTLL12,CCAR1,NUDC,VHL,ATXN1,UBE2V1,ZFR,DHX15,TARS,CAND1,ZHX1,ZC3H7B,SIAH2,PDLIM5,HIPK3,SSSCA1 |
| 1.923e-04 | -8.56 | FAF1 (Fas associated factor 1) | protein interactions | 11124 | 132 | 38 | 17029 | 2761 |
HSPH1,UGP2,UBR2,RAE1,CDT1,UBXN1,UROD,YTHDF3,CUL1,CSNK2A1,XPO7,CDC73,NPLOC4,RAD23A,RAP1A,GART,NSFL1C,RPN2,CARM1,CDC5L,TK1,MIOS,CUL3,DNAJA1,FADD,CBX3,FAS,HSPA4,DDOST,UBXN2B,WDR59,PPM1G,KBTBD7,VCPIP1,ASNA1,USP11,NGLY1,FAF1 |
| 1.924e-04 | -8.56 | GSE38681_WT_VS_LYL1_KO_LYMPHOID_PRIMED_MULTIPOTENT_PROGENITOR_DN | MSigDB lists | GSE38681_WT_VS_LYL1_KO_LYMPHOID_PRIMED_MULTIPOTENT_PROGENITOR_DN | 196 | 49 | 17377 | 2626 |
FAM208B,PARP12,TMEM184B,KIAA0100,HLA-E,TOR3A,TOR1AIP1,GADD45G,TAP1,ARID5A,AGFG1,CMTM6,RGS1,IRF4,PDCD10,CLIC4,VMP1,ARL6IP1,NUP153,RNF19A,STAT3,PPA1,MORC3,STAU1,TRAFD1,RFC3,DDX24,BIRC3,NUDT4,WDHD1,WIPF1,TOR1AIP2,SLC25A22,MCL1,KCNQ1,ASB13,OGFR,PSMB9,ISG15,ARF4,FAS,SCARB2,TRIM26,KPNA1,RBL1,STAT1,PML,SLC16A1,RNF114 |
| 1.924e-04 | -8.56 | REACTOME_ANTIGEN_PROCESSING_UBIQUITINATION_PROTEASOME_DEGRADATION | MSigDB lists | REACTOME_ANTIGEN_PROCESSING_UBIQUITINATION_PROTEASOME_DEGRADATION | 196 | 49 | 17377 | 2626 |
UBE2D3,UBE2E2,TRIP12,UBR2,TRIM11,CUL1,UBE2Z,UBE2Q1,UBE4A,PSMD9,FBXO3,PSMD2,PSMD1,UBE2Q2,PSMA6,KLHL20,HUWE1,UBA5,ANAPC7,UBE3B,UBE3C,LRSAM1,ASB6,UBE2M,PSMA8,RBX1,VHL,RNF25,CUL3,PSMB7,PSMA1,ANAPC2,CDC23,ASB13,PSMB9,PSMB3,PSMC4,KEAP1,CDC16,CDC27,RPS27A,PSMD8,PSMD3,TPP2,TRIM32,UBE2C,SMURF1,PSMC1,ANAPC4 |
| 1.929e-04 | -8.55 | GO_POSITIVE_REGULATION_OF_MOLECULAR_FUNCTION | MSigDB lists | GO_POSITIVE_REGULATION_OF_MOLECULAR_FUNCTION | 1723 | 312 | 17377 | 2626 |
TXN,ADD1,TSC2,CUL1,CCNL2,CCNB1,UBE2I,ELMOD2,PARK7,CALM2,CDK5,ASAP2,PSMD1,RABGAP1L,RAB4A,DNM2,CDC25B,PLCL2,SENP1,BAK1,AKT2,TOPORS,AURKB,DCUN1D5,RFC2,ARF4,KRIT1,MAP3K4,MID1IP1,RPS27A,PSMD8,AXIN1,ITGB1,OGT,TRIM52,TRAF5,DDX58,HSPH1,MAPRE1,GMFG,CLSPN,CHTF18,RHOC,GADD45G,PRKAA1,VAV2,TRIO,ACAP1,CYCS,PSEN1,PSMD9,APH1B,JMY,CFLAR,DDRGK1,FKBP1A,TFAP4,SNX18,DAPK1,MSH2,GNAI2,TERF2,MAPKAPK3,MFNG,ADRB2,CYFIP2,MAP2K2,PSMB3,FAS,DERL1,CAT,FNTA,GOLGA2,CSK,CEBPG,ARAP1,CNOT6,MAP3K5,CDKN2A,ALS2,RHOG,ANKRD27,TRIP10,RAF1,RAC1,MAGED1,ANK3,TPX2,TBC1D13,PRKACA,APP,TERF2IP,CRKL,SHC1,SP100,SH3BP1,TBC1D22A,RALB,TBC1D14,ADCY9,CDKN1B,ANAPC7,MAVS,ATF2,ADCY7,CCT2,RFC3,PSRC1,EDF1,CDC23,RAB1A,PSMB9,ERC1,PPP2CA,CDC16,JAK1,HIPK2,CORO1C,RPLP1,TICAM1,TRIM32,PITRM1,XRCC4,LRP8,RHEBL1,PKP4,RPS2,DEPDC1,ZFP91,TCF3,FLOT1,GTF2F1,CCNK,PSMD2,PDCD10,PTEN,AHSA1,ARHGEF1,PTPN11,AXIN2,DCP1A,MAP3K14,NCOA2,MSH6,SPTAN1,PDPK1,PPP3CA,KAT2A,NET1,DENND1B,NEK7,DENND4C,JTB,RABIF,ANAPC2,PACS1,RAB3IP,ZP3,MARK2,PICALM,FADD,SMAP2,PRDX3,PML,HMGB2,RGL1,PSAP,CD81,ANAPC4,CCNC,AGRN,NF1,DNAJC24,SIRT2,AGFG1,S1PR2,MAPK14,GIT2,ABL2,RAP1A,PCNA,CDC42,PIK3R2,RP2,TCEA1,MTPN,TRIM14,COPS8,PLK1,TRIM8,APH1A,NCK1,GMFB,UBE2V1,CDC6,ARHGDIB,LRP5,PRKRA,ABHD5,EPB41,TBC1D17,ADAM9,BAZ1B,CAB39,ZNF268,STK11,CLU,PSMC1,POT1,TBC1D12,PPP1R12A,PHB2,GORASP1,CIB1,LAMTOR3,RACGAP1,DNAJB1,RGS2,DOCK11,RAPGEF6,APOPT1,RINL,BUD31,BCL2,MDFIC,PREB,CYTH1,TRAPPC9,PSMA1,MAP4K3,KRAS,ARHGAP15,RXRB,MASTL,PSMC4,GNAS,TSC1,CDC27,CTSA,MYO9A,TRAF7,TOR1AIP1,SMARCA4,LYN,BCAP31,VAV1,PSMA6,NVL,PIN1,KIF14,PDCD2,CHTOP,F2R,ABI1,HTRA2,DVL2,GM2A,ARHGAP17,TIMP2,PSMA8,RNF25,PSMB7,DNAJC9,TOR1AIP2,DNAJC10,TAB2,PLEKHG4B,PSMD3,GADD45B,SCARB1,MAPK1,MIF,GCLM,DNAJC2,SMAP1,SH2D3A,DAP,DBF4,PAWR,ARF1,MYO9B,DCUN1D4,RGS1,FBXO5,FGFR3,IRF4,CTSS,ARHGEF2,STAT3,CAMK2G,TGFB1,TELO2,ADAM17,RHOA,PRKAR1B,RANGAP1,ARHGEF12,MEN1,MAPK3,HSPA1B,TRIM26,PDCD6,PLAA,ELMO1,OSBPL8,PKD2,TAF12,ARHGAP23,UBE2C,HRAS,IFI16,RAB3IL1 |
| 1.933e-04 | -8.55 | DROSHA (drosha ribonuclease III) | protein interactions | 29102 | 39 | 16 | 17029 | 2761 |
PDCD6,HNRNPAB,ZCCHC8,NCK1,DGCR8,HNRNPUL2,U2SURP,CUL3,PSMA1,DDX5,SMC2,THRAP3,MEN1,CARM1,RPA1,SRPK2 |
| 1.933e-04 | -8.55 | DUSP1 (dual specificity phosphatase 1) | protein interactions | 1843 | 39 | 16 | 17029 | 2761 |
SRM,HSPA4,DUSP3,TMEM97,ABHD14B,MTMR12,COX4I1,ICMT,AP3S1,MAPK1,ZNRD1,MAPK14,EYA2,PARK7,HDDC2,MAPK3 |
| 1.933e-04 | -8.55 | AP4M1 (adaptor related protein complex 4 subunit mu 1) | protein interactions | 9179 | 39 | 16 | 17029 | 2761 |
GALNT2,SUV39H2,ARID2,TIMM29,AKT2,ZBTB22,TGOLN2,MRPL48,ARF1,WDR76,H3F3A,AP4E1,CDK11A,CBX4,DDX52,SF3B2 |
| 1.933e-04 | -8.55 | ZNF414 (zinc finger protein 414) | protein interactions | 84330 | 39 | 16 | 17029 | 2761 |
TERF2IP,AGGF1,GOLGA2,KDM4A,DHPS,MTMR4,ATG3,PBK,KBTBD7,THNSL1,ERBIN,ZRANB1,AHCYL1,SHCBP1,EDRF1,PPP2R2D |
| 1.949e-04 | -8.54 | GOLDRATH_NAIVE_VS_MEMORY_CD8_TCELL_UP | MSigDB lists | GOLDRATH_NAIVE_VS_MEMORY_CD8_TCELL_UP | 191 | 48 | 17377 | 2626 |
SLC12A7,SRM,RMND5A,CYTIP,ARID2,DAP,SRSF6,UCK2,TKT,KIF23,ADPGK,CCNL2,RBM4,BZW2,INTS7,HDAC7,IL6ST,TTC3,RNF19A,MINPP1,TALDO1,TMEM14C,SMC4,NTPCR,RPRD1A,PRKDC,MAP4K4,ILF3,EZR,UBE4B,RAB3IP,EIF4G2,MARK2,CYB5A,ISG15,RBM38,GEMIN5,UTP20,HSPB11,ATP1A1,ATP6V1D,PPP2R5A,TWSG1,PRPS2,PPA2,TCOF1,HDAC2,TUBB |
| 1.949e-04 | -8.54 | GSE17721_POLYIC_VS_GARDIQUIMOD_4H_BMDC_DN | MSigDB lists | GSE17721_POLYIC_VS_GARDIQUIMOD_4H_BMDC_DN | 191 | 48 | 17377 | 2626 |
UBE2D3,MMACHC,TMED7,PRKAB1,NDUFB6,SLC41A1,USP39,SLC4A2,IRF3,CDC42SE2,UBE4A,SNRPD3,TMEM165,STAM,APP,PAIP1,UBXN2A,C18orf32,MED10,BTF3L4,CABLES2,ATF2,LRRC59,DVL2,TMX1,ABCC1,RBM15B,ACSL5,RHOA,TNFAIP3,NCK1,PSPC1,RDH10,CYFIP2,CCT8,CYB5A,NUCB1,ACYP1,TPP2,ACLY,TBPL1,PGRMC1,PGAM1,ZNF598,IPO4,SLC25A33,NUMB,PDF |
| 1.949e-04 | -8.54 | GSE36476_CTRL_VS_TSST_ACT_16H_MEMORY_CD4_TCELL_YOUNG_DN | MSigDB lists | GSE36476_CTRL_VS_TSST_ACT_16H_MEMORY_CD4_TCELL_YOUNG_DN | 191 | 48 | 17377 | 2626 |
SEPHS2,SRM,GCLM,IMMT,TXN,NQO1,ADO,TAP1,UCK2,ZFYVE21,CYCS,SND1,SAC3D1,FARSA,RNF121,IRF4,ATP6V0B,PPCDC,DAPK1,MAP3K14,TALDO1,PTPRK,CCT2,CREG1,IDH3A,WDR18,BMS1,TARS,MFN2,PSMC4,YIF1A,RAD51C,SLCO4A1,MTHFD2,TIMM13,RBM47,NIP7,STT3A,TBL3,NUP62,ATF6,RUVBL2,PDCD11,PITRM1,PGAM1,HRAS,BYSL,IPO4 |
| 1.949e-04 | -8.54 | GSE15330_WT_VS_IKAROS_KO_HSC_UP | MSigDB lists | GSE15330_WT_VS_IKAROS_KO_HSC_UP | 191 | 48 | 17377 | 2626 |
MIB2,USP7,PARP12,IVNS1ABP,SLC41A1,FAM53C,XIAP,PCSK7,CHIC2,MYO9B,RAB6A,SEC16A,ETS1,SEC11A,CAPN2,GSTK1,PDK2,MDM2,CTSS,NUP210,PTEN,CAPZA1,SRI,UPF2,OSTF1,SMC4,DPM1,SELPLG,GBA,TUBGCP5,ARHGDIB,DNAJA1,SYVN1,PLEC,MARK2,RHOB,ARF4,NECAP2,GRIPAP1,RBMX,ACOX1,CSNK1G1,OAZ2,ARRDC1,LY75,SAMD8,ZNF830,LONP2 |
| 1.950e-04 | -8.54 | CCT5 (chaperonin containing TCP1 subunit 5) | protein interactions | 22948 | 174 | 47 | 17029 | 2761 |
UNK,IMMT,CYLD,POC1A,WDTC1,CDC73,SSR1,CDK5,RFWD3,PSMA6,IARS,HUWE1,CRY2,AHCYL1,ATF2,MCPH1,SEH1L,NIPSNAP1,CDC5L,RPAP3,MOB4,TXNL1,CCT2,DCAF8,VHL,CUL3,WDR82,BRCA1,MCM2,TRIM28,CCT8,TARS,PPP2CA,TBC1D17,AHNAK,KBTBD7,DCAF11,H2AFX,ACTB,PRPF4,FUS,WDR76,CDK2,IGBP1,PPP2R2D,DCAF5,SSSCA1 |
| 1.954e-04 | -8.54 | Interleukin-11 Signaling Pathway | WikiPathways | WP2332 | 44 | 17 | 5312 | 837 |
TGFB1,PDPK1,RAF1,RPS6KA1,MAP2K2,MAPK3,JAK1,BIRC5,IL6ST,PIK3R2,STAT1,PTPN11,BCL2,CREB1,MAPK1,STAT3,HRAS |
| 1.956e-04 | -8.54 | TOMM40 (translocase of outer mitochondrial membrane 40) | protein interactions | 10452 | 123 | 36 | 17029 | 2761 |
COX5B,IMMT,TOMM20,NDUFS1,KRBA1,PHB2,LAMTOR3,CHCHD2,NDUFA4,DUSP22,FKBP1A,NDUFV1,NDUFA2,AP2B1,SEPT11,TAGLN2,CYC1,RNF5,TIMM50,BAK1,VDAC2,MTX1,NDUFA7,VDAC1,EIF3A,CHCHD3,SDHB,HSPA4,MRPL55,QARS,PRDX5,YJU2,CAB39,NUP58,ANXA11,FUBP1 |
| 1.958e-04 | -8.54 | PDCD6IP (programmed cell death 6 interacting protein) | protein interactions | 10015 | 114 | 34 | 17029 | 2761 |
MIF,USP7,PDCD6IP,TKT,LACTB2,CNTROB,WDR5,SPR,MCTS1,WWP2,GSTK1,UBA5,SRI,AHCYL1,TFG,F2R,HTRA2,ABCC1,CUL3,EZR,BRCA1,PEF1,GLOD4,CHMP4A,PDCD6,KEAP1,CEP55,MAPK6,ARRDC1,CHMP4B,GPI,MAPK1,TUBB,IFI16 |
| 1.969e-04 | -8.53 | GO_INTRINSIC_APOPTOTIC_SIGNALING_PATHWAY | MSigDB lists | GO_INTRINSIC_APOPTOTIC_SIGNALING_PATHWAY | 146 | 39 | 17377 | 2626 |
SART1,TMEM109,CUL1,CYCS,BCL2L1,APOPT1,MOAP1,PDK2,PDCD10,SIVA1,XPA,MSH2,BCL2,FNIP2,TP53BP2,HTRA2,MSH6,BAK1,PGAP2,PRKDC,CUL3,TOPORS,MCL1,BRCA1,DNAJC10,HINT1,HIPK2,E2F1,PML,AEN,DDX5,STK11,CHEK2,CLU,MAP3K5,E2F2,ZMAT3,HRAS,IFI16 |
| 1.970e-04 | -8.53 | GSE40274_XBP1_VS_FOXP3_AND_XBP1_TRANSDUCED_ACTIVATED_CD4_TCELL_DN | MSigDB lists | GSE40274_XBP1_VS_FOXP3_AND_XBP1_TRANSDUCED_ACTIVATED_CD4_TCELL_DN | 186 | 47 | 17377 | 2626 |
INTS2,SRM,UBE2E2,PHB2,URB2,MAGED1,TIA1,LANCL1,CHD1,PIP4K2A,TMCC3,LYAR,ZNHIT6,MECR,TTC3,TTLL12,SLC35A1,PPA1,SEH1L,JMJD4,METTL1,UBQLN4,EHMT1,ZBED5,ADSL,MTX1,NUTF2,GSTCD,GAR1,ODC1,DDX39A,TRIM28,ZMYM3,AKAP1,CBX3,TAF2,PEX5,ETS2,TFDP1,WDR4,PROSER1,KHSRP,RRS1,BYSL,GPATCH4,TUBB,DDB1 |
| 1.970e-04 | -8.53 | GSE10240_IL22_VS_IL17_STIM_PRIMARY_BRONCHIAL_EPITHELIAL_CELLS_DN | MSigDB lists | GSE10240_IL22_VS_IL17_STIM_PRIMARY_BRONCHIAL_EPITHELIAL_CELLS_DN | 186 | 47 | 17377 | 2626 |
MBD1,WSB2,SEPHS2,GCLM,NAT9,SKA3,SMAP1,GOLIM4,CYLD,DEPDC1,RACGAP1,NANS,NCKAP1,WRB,SPAG5,ATG4A,KRI1,ATP6V0B,MED8,CRY2,MCPH1,GCC1,SRP72,MND1,TCTEX1D2,ELL2,OAF,NSDHL,COQ10B,SLC16A7,HTATIP2,GORASP2,GAR1,RAD54B,MASTL,MYO1F,C1orf122,CCDC127,NEIL3,GADD45B,TYW5,ERGIC3,RBMS1,ATP6V0C,FAM126A,CHEK2,GPI |
| 1.970e-04 | -8.53 | GSE19401_NAIVE_VS_IMMUNIZED_MOUSE_PLN_FOLLICULAR_DC_UP | MSigDB lists | GSE19401_NAIVE_VS_IMMUNIZED_MOUSE_PLN_FOLLICULAR_DC_UP | 186 | 47 | 17377 | 2626 |
NCOR2,IVNS1ABP,TSC22D3,ARID5A,FLOT1,DNAJB1,RBM4,RGS1,LMNA,CREM,PTPN2,CAPN2,SP100,CDC42,EIF4A3,ATP13A3,RPN2,TP53BP2,SLC12A2,TIPARP,CDC37,PPIF,RPL35,BTG2,SLC16A7,ITM2A,EMP3,EZR,PRKRA,EIF4H,MACF1,DHX15,RHOB,PSMC4,EIF3K,SH3BP5,HINT1,UAP1,SAFB,PPP3R1,RBMS1,YWHAZ,TICAM1,SRSF3,PLOD3,CSNK1D,ZC3HAV1 |
| 1.970e-04 | -8.53 | GSE23505_IL6_IL1_VS_IL6_IL1_IL23_TREATED_CD4_TCELL_UP | MSigDB lists | GSE23505_IL6_IL1_VS_IL6_IL1_IL23_TREATED_CD4_TCELL_UP | 186 | 47 | 17377 | 2626 |
C1orf112,KIF23,RACGAP1,KIF2C,PMF1,BRIX1,REPS1,PARK7,NUP205,MIS12,RFWD3,OIP5,LYAR,CAPN2,SUV39H2,SAR1A,EIF4A3,PTEN,IMPAD1,KIF14,SEPT11,LRRC59,NUP85,RHOA,NASP,ASPM,NUDT4,SEPT8,WDHD1,EMP3,ANAPC2,MAP7D1,EXOSC9,PITPNB,IL12RB1,PICALM,NUCB1,AHNAK,PALB2,RAD18,NSMCE2,ARNTL,NRM,CEP55,CCNB2,LRP8,BYSL |
| 1.970e-04 | -8.53 | GSE36888_STAT5_AB_KNOCKIN_VS_WT_TCELL_IL2_TREATED_6H_DN | MSigDB lists | GSE36888_STAT5_AB_KNOCKIN_VS_WT_TCELL_IL2_TREATED_6H_DN | 186 | 47 | 17377 | 2626 |
DNMT3A,MAPRE1,HJURP,TPX2,NIPA2,KIF2C,CHAC2,MXD4,WDR5,PDXDC1,XPR1,CEP104,ZNF473,CCP110,GLIS2,CENPJ,SSBP3,ZNF326,CNPY4,RNF26,LRRC59,DNMT1,MGAT5,ARL5A,MSH6,SMC4,SOCS5,MKLN1,PRIM2,KLF10,SLBP,PRPF3,PTTG1IP,ZFAND5,KIF11,RHOB,CDCA4,CDC27,DGCR8,OSBPL8,H2AFX,ANP32E,EHD4,SASS6,GLCCI1,ZNF598,PDCD4 |
| 1.970e-04 | -8.53 | GSE339_EX_VIVO_VS_IN_CULTURE_CD4POS_DC_DN | MSigDB lists | GSE339_EX_VIVO_VS_IN_CULTURE_CD4POS_DC_DN | 186 | 47 | 17377 | 2626 |
WSB2,UBE2D3,CCNC,UBL3,TMED7,H2AFZ,SLC41A1,DNAJB2,SRGN,UBE2Z,AGFG1,AP3S1,KCMF1,KTN1,LMNA,CFLAR,SRXN1,ANKRD28,HNRNPA2B1,IRF4,MDM2,IMPAD1,LPIN2,RAD23B,PPP6C,PTGES3,LRRC59,STAT3,CCAR1,FTL,ADAM17,ELL2,RBX1,RAB7A,MAP4K4,TOR1AIP2,KRAS,ZP3,PRDX1,ARF4,ADSS,KIF2A,GOLGA4,AHNAK,PSMD8,GCSH,ANXA11 |
| 1.970e-04 | -8.53 | GSE3982_EOSINOPHIL_VS_NEUTROPHIL_UP | MSigDB lists | GSE3982_EOSINOPHIL_VS_NEUTROPHIL_UP | 186 | 47 | 17377 | 2626 |
TCF12,CCNC,MRPL9,GOLIM4,YTHDC2,SMARCA4,FAM136A,LYRM2,METTL3,STAM,PDXDC1,SRRT,NUP205,FASTKD3,PSMD1,MEX3C,SIAH1,YBX1,JOSD1,ABCD1,MRPL40,ACAD8,FBL,PRPF19,CDC37,PHF10,ABHD2,CSRP1,NUDT4,VHL,TYW1,CRNKL1,MRPL16,NUP155,TOLLIP,API5,MATR3,TARS,CLNS1A,USP36,PRDX1,GLOD4,FBXO21,COIL,ABCA1,NRBP1,TMEM131 |
| 1.975e-04 | -8.53 | BURTON_ADIPOGENESIS_12 | MSigDB lists | BURTON_ADIPOGENESIS_12 | 30 | 13 | 17377 | 2626 |
SP3,KIF2A,IMPAD1,LUC7L3,CAPN7,MKI67,ARGLU1,ROCK1,ARID1A,FAM76B,MYEF2,HNRNPM,SRSF10 |
| 1.975e-04 | -8.53 | REACTOME_NEGATIVE_REGULATORS_OF_RIG_I_MDA5_SIGNALING | MSigDB lists | REACTOME_NEGATIVE_REGULATORS_OF_RIG_I_MDA5_SIGNALING | 30 | 13 | 17377 | 2626 |
OTUD5,DDX58,UBE2D3,CYLD,TNFAIP3,RPS27A,PIN1,NLRC5,IRF3,MAVS,RNF135,ISG15,PCBP2 |
| 1.975e-04 | -8.53 | GO_ORGANELLAR_LARGE_RIBOSOMAL_SUBUNIT | MSigDB lists | GO_ORGANELLAR_LARGE_RIBOSOMAL_SUBUNIT | 30 | 13 | 17377 | 2626 |
MRPL2,MRPL55,MRPL27,MRPL12,MRPL43,MRPL16,MRPL11,MRPL21,MRPL13,NSUN4,MRPL19,MRPL3,MRPL32 |
| 1.982e-04 | -8.53 | STIL (STIL, centriolar assembly protein) | protein interactions | 6491 | 92 | 29 | 17029 | 2761 |
RPAP3,USP7,HSPH1,DCAF15,MAGED1,TKT,YTHDF3,CUL1,RRM2,MTMR6,DNAJA1,ARID1B,CNOT3,EDC3,SUPT16H,PCM1,UPF1,CDC16,HINT1,PFDN4,CENPJ,SEC24C,PIN1,VCPIP1,GPATCH1,BTF3,SMG9,SASS6,CDC37 |
| 1.985e-04 | -8.52 | Coro1c (coronin, actin binding protein 1C) | protein interactions | 23790 | 146 | 41 | 17029 | 2761 |
RHOG,CHMP2A,ADD1,PPP1R12A,LUZP1,ACTR3,RAC1,FLOT1,TWF2,LYN,TFRC,XPR1,DST,CD59,RAP1A,CCDC50,RALB,ARPC5,CAPZA1,CLTB,CSNK1G3,CFL1,MYO5A,EEF1D,DCTN1,SPTAN1,CDC37,PPP1R9B,RHOA,WDR1,KRAS,CAPZA2,RAB1A,DAPK3,GNAS,INF2,AHNAK,MYO18A,HMGB2,FAM126A,CHMP4B |
| 1.988e-04 | -8.52 | GSE15330_HSC_VS_GRANULOCYTE_MONOCYTE_PROGENITOR_DN | MSigDB lists | GSE15330_HSC_VS_GRANULOCYTE_MONOCYTE_PROGENITOR_DN | 181 | 46 | 17377 | 2626 |
BCCIP,HIVEP3,ZNF296,KLHL21,SHPRH,CXXC1,MEF2A,TBC1D13,IRF3,ADPGK,NCKAP1,DAZAP2,ATP6V1B2,IL21R,ANKIB1,APP,SAC3D1,ATP6V0B,SIAH1,SNX18,AP3S2,NSFL1C,INTS12,ZBTB22,POLR1B,ERI3,SLC12A2,SAP30L,AMPD2,ARHGAP17,GABPA,RFFL,COMMD4,LSG1,RAB2B,LEMD2,PEX5,SEC23IP,TAB2,GPS2,SAFB,OGT,AEN,ASNA1,TSPAN5,NUDT3 |
| 1.988e-04 | -8.52 | GSE41176_UNSTIM_VS_ANTI_IGM_STIM_TAK1_KO_BCELL_1H_UP | MSigDB lists | GSE41176_UNSTIM_VS_ANTI_IGM_STIM_TAK1_KO_BCELL_1H_UP | 181 | 46 | 17377 | 2626 |
ZNF207,SARNP,MUT,TMBIM4,CDK2AP2,DCTN2,GSPT2,ACAP1,LAMTOR3,SDF2L1,TMED3,GYG1,MYEF2,RHBDD1,PNO1,NDUFS7,SSR1,GTPBP3,MCM5,PHF14,AP1M1,GPATCH1,NDUFB9,APOOL,ALDH18A1,NAA35,S100A6,PREB,TXNL1,ERCC1,METTL5,ATXN1,NFATC2,TMEM147,ZNF407,CBFB,ARHGAP15,TMEM184C,MBIP,MRPL55,DGCR8,MBOAT1,SMG9,FAM208A,PURA,FAF1 |
| 1.988e-04 | -8.52 | GSE16755_CTRL_VS_IFNA_TREATED_MAC_UP | MSigDB lists | GSE16755_CTRL_VS_IFNA_TREATED_MAC_UP | 181 | 46 | 17377 | 2626 |
TCF12,MANBA,GADD45G,ALKBH5,UBE4A,INO80E,XPO7,TWF2,GGPS1,GIT2,MBD4,NFATC3,DUS4L,PPIG,TBC1D14,FUT8,KIFAP3,ANAPC7,ZRANB1,DNMT1,ARID4A,DRAM2,ABCC5,TRIM8,MIOS,ATP6V0A1,DNAJC9,NUP155,KDM3A,PHF6,ZMYM3,CBX3,DDX17,EPB41,MRPL55,DSN1,VPS26B,SNAP23,APPL2,ZDHHC7,MRFAP1L1,TRIM32,GLCCI1,PDSS2,PTDSS1,TIGD2 |
| 1.988e-04 | -8.52 | GSE30971_CTRL_VS_LPS_STIM_MACROPHAGE_WBP7_HET_4H_DN | MSigDB lists | GSE30971_CTRL_VS_LPS_STIM_MACROPHAGE_WBP7_HET_4H_DN | 181 | 46 | 17377 | 2626 |
RMND5A,REPS2,VPS45,GLUD1,PMF1,THRAP3,DNAJB1,GGA2,ITGB5,SRRT,PIP4K2A,ATPAF1,LMNA,GTF2F1,PCNA,SRSF4,XPA,PARL,RNF135,TNRC18,DNMT1,ATP6V0D1,TRIM14,IMPA2,DRAM2,RPAP3,MLEC,TACC1,PPT1,DRAP1,RFXANK,ABHD11,RHOT1,FOXRED1,MACF1,PON2,HSPB11,POLR2J,TMED10,GPS2,VPS26B,ACLY,ZDHHC7,RGL1,REEP4,RNF114 |
| 1.988e-04 | -8.52 | GSE25088_WT_VS_STAT6_KO_MACROPHAGE_ROSIGLITAZONE_AND_IL4_STIM_UP | MSigDB lists | GSE25088_WT_VS_STAT6_KO_MACROPHAGE_ROSIGLITAZONE_AND_IL4_STIM_UP | 181 | 46 | 17377 | 2626 |
PDCD6IP,SUCLG1,GSPT2,DBF4,CDCA3,GGA2,DUSP22,SLC20A1,MRPL19,MEAF6,RPL23A,PRNP,EIF2S2,SAR1A,CWC27,THAP4,LRRC8D,ZBTB22,NSUN4,TACC3,SAP30,ZDHHC18,NRAS,LAP3,PBK,PCGF6,DDX20,DCTD,MTR,TRIM28,RAD54B,DAP3,POLE,CCDC6,PFDN4,RBL1,DGCR8,ACLY,C4orf46,XRCC3,KPNA2,TMEM159,SASS6,PITRM1,CD81,SLC25A39 |
| 1.990e-04 | -8.52 | GSE15624_CTRL_VS_3H_HALOFUGINONE_TREATED_CD4_TCELL_UP | MSigDB lists | GSE15624_CTRL_VS_3H_HALOFUGINONE_TREATED_CD4_TCELL_UP | 151 | 40 | 17377 | 2626 |
UBL3,MIF4GD,GPR132,SYS1,NQO1,UBR2,SNX15,BRAP,EPN1,SIKE1,SEC16A,MAPK14,CRLF3,XPR1,ABHD16A,C1GALT1,NFATC3,STRBP,PPP4R1,AXIN2,SGCB,PLK3,CSNK1G2,TRAFD1,KAT2A,TNFAIP3,HTATIP2,RFFL,RCOR1,KRAS,PBRM1,AMDHD2,AZI2,PICALM,MTMR3,CACNB1,SMAD2,FBXO28,BRD2,MLYCD |
| 1.995e-04 | -8.52 | BIOCARTA_HIVNEF_PATHWAY | MSigDB lists | BIOCARTA_HIVNEF_PATHWAY | 58 | 20 | 17377 | 2626 |
BIRC3,CASP6,PRKDC,XIAP,ARHGDIB,CYCS,CDK11B,PSEN1,CDK11A,BIRC2,FADD,LMNA,CFLAR,FAS,RB1,MDM2,BCL2,MAP3K14,MAP3K5,SPTAN1 |
| 1.995e-04 | -8.52 | GO_ER_ASSOCIATED_UBIQUITIN_DEPENDENT_PROTEIN_CATABOLIC_PROCESS | MSigDB lists | GO_ER_ASSOCIATED_UBIQUITIN_DEPENDENT_PROTEIN_CATABOLIC_PROCESS | 58 | 20 | 17377 | 2626 |
SEC61B,TMUB1,ERLIN1,DNAJB2,MAN1B1,SDF2L1,SYVN1,UBQLN2,EDEM2,DNAJB9,NPLOC4,RNF103,PSMC4,DERL1,ANKZF1,DNAJC10,RNF121,SEL1L,PSMC1,RNF5 |
| 2.000e-04 | -8.52 | ficolin-1-rich granule lumen | cellular component | GO:1904813 | 124 | 34 | 18223 | 2701 |
MIF,GMFG,PDAP1,ASAH1,CDK13,GYG1,MAPK14,KCMF1,GNS,PSMD2,CTSS,ARPC5,HUWE1,OSTF1,MVP,TIMP2,PPIE,PSMB7,C1orf35,PKM,CCT8,CAND1,HSPA1B,CAT,PSMD3,ACLY,CANT1,CAB39,IMPDH1,GPI,LTA4H,MAPK1,PGAM1,CAPN1 |
| 2.001e-04 | -8.52 | oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor | molecular function | GO:0016655 | 53 | 19 | 17224 | 2647 |
NDUFA5,NDUFV2,NDUFS1,NQO1,NDUFB6,NDUFAF2,NQO2,NDUFA4,NDUFA7,NDUFB1,NDUFS7,NDUFS4,NDUFV1,NDUFA2,NDUFB4,NDUFB9,NDUFS8,NDUFS5,NDUFA3 |
| 2.001e-04 | -8.52 | GSE42724_NAIVE_VS_B1_BCELL_DN | MSigDB lists | GSE42724_NAIVE_VS_B1_BCELL_DN | 176 | 45 | 17377 | 2626 |
COX5B,RPS2,SUCLG1,MRPS2,DCTN2,LAGE3,RPL15,SIRT2,TMED3,SND1,PABPC4,ASAP2,NUP210,IMPAD1,MEA1,MRPS27,MRPL48,OSTC,FBL,TOP1MT,GPD1L,TIMM50,SRP72,EIF3L,RPL29,SEC61B,TIMMDC1,PRKDC,RPL8,VDAC2,MRPL12,LRRC8A,TMEM147,RHOT2,RPSA,EIF3K,SYNCRIP,TIMM17A,EIF2D,LRPPRC,UQCRH,IDH3B,HIGD2A,DDB1,PTOV1 |
| 2.001e-04 | -8.52 | GSE42724_NAIVE_BCELL_VS_PLASMABLAST_DN | MSigDB lists | GSE42724_NAIVE_BCELL_VS_PLASMABLAST_DN | 176 | 45 | 17377 | 2626 |
ZBED3,KCTD7,UBE2E2,FEZ2,GNPDA1,C1orf112,ANKH,DCUN1D4,AP3S1,PITHD1,ATPAF1,ASPHD2,TET3,CAPN2,STARD9,NFATC3,SNX18,TCEA1,DNMT1,IMPA2,ADCY7,NAGPA,MLEC,SEPT9,TACC1,RAB7A,DENND4C,EMB,CCDC34,PDE3B,NDRG3,ARHGAP15,DHX57,SOCS7,MAN2A2,PWWP2B,HHEX,TMEM168,CSK,CCDC14,CDCA7L,VCPIP1,CHEK2,CHPT1,RTN3 |
| 2.001e-04 | -8.52 | GSE37533_PPARG1_FOXP3_VS_PPARG2_FOXP3_TRANSDUCED_CD4_TCELL_DN | MSigDB lists | GSE37533_PPARG1_FOXP3_VS_PPARG2_FOXP3_TRANSDUCED_CD4_TCELL_DN | 176 | 45 | 17377 | 2626 |
HECA,MAX,SF3B1,B4GALT5,TRIO,CIB1,MCCC1,AP3M2,CDK13,CCNL2,MAPK14,METTL3,HMG20A,C2orf68,PAIP2,RPL23A,STARD9,CLUAP1,PPCDC,CORO1A,FBL,MOB1A,MTPN,FYTTD1,TTPAL,CYTH1,TRIM8,BIRC3,FAM49B,KIAA0040,CUL3,LDHA,RNPS1,WIPF1,ICAM2,RAB5B,SLTM,DHX15,SMAP2,LUC7L3,PQBP1,PRPF4,FAM208A,RNF139,FUBP1 |
| 2.002e-04 | -8.52 | positive regulation of protein ubiquitination | biological process | GO:0031398 | 107 | 31 | 17256 | 2622 |
PLK1,RPS2,BIRC3,PHF23,GORASP1,XIAP,CUL3,TOPORS,DCUN1D5,ADRB2,BRCA1,RAB1A,PTTG1IP,DCUN1D4,PEF1,BIRC2,FANCI,FBXO5,DERL1,FKBP1A,PDCD6,HSPBP1,GOLGA2,PTEN,MTA1,PIN1,AXIN1,CTR9,TICAM1,ARRB2,UBE2C |
| 2.005e-04 | -8.51 | REACTOME_ANTIGEN_PROCESSING_CROSS_PRESENTATION | MSigDB lists | REACTOME_ANTIGEN_PROCESSING_CROSS_PRESENTATION | 71 | 23 | 17377 | 2626 |
SEC61B,PSMA8,SEC61G,TAP1,PSMB7,PSMA1,ITGB5,PSMB9,PSMD9,PSMB3,HLA-A,PSMC4,HLA-B,PSMD2,PSMA6,CTSS,PSMD1,SEC61A1,RPS27A,PSMD8,PSMD3,TAP2,PSMC1 |
| 2.007e-04 | -8.51 | ERAD pathway | biological process | GO:0036503 | 84 | 26 | 17256 | 2622 |
SEC61B,TMUB1,ATXN3,ERLIN1,MAN1B1,UBE4B,SYVN1,SDF2L1,UBE4A,UBQLN2,EDEM2,RHBDD1,DNAJB9,NPLOC4,RNF103,PSMC4,DERL1,ANKZF1,DNAJC10,RNF121,SEL1L,ECPAS,RNF139,PSMC1,RNF5,USP13 |
| 2.010e-04 | -8.51 | GSE9988_ANTI_TREM1_VS_CTRL_TREATED_MONOCYTES_UP | MSigDB lists | GSE9988_ANTI_TREM1_VS_CTRL_TREATED_MONOCYTES_UP | 171 | 44 | 17377 | 2626 |
GCLM,TXN,GNPDA1,KLHL21,ADO,XIAP,RRAGC,ATP6V1B2,TFRC,RGS1,SPAG5,SRXN1,ANKRD28,MOAP1,DTL,ABL2,HOMER1,SNUPN,NAA50,FNIP2,CLDND1,RNF19A,RYBP,TCTEX1D2,KLF10,LONRF3,ELL2,COQ10B,ACSL3,RIT1,RAB1A,RHEB,NEU1,SH3BP5,SLCO4A1,ETS2,DUSP3,MAFK,GADD45B,MAPK6,DDX5,USP53,ZC3HC1,ESYT2 |
| 2.012e-04 | -8.51 | GCM_MLL | MSigDB lists | GCM_MLL | 161 | 42 | 17377 | 2626 |
DDX47,RBM8A,TIA1,ATG2B,FOXO3,GFM2,ABHD16A,SAP130,MTMR4,PPIG,PRDM4,CS,TNPO2,ZBTB22,TARDBP,TTC17,CHTOP,CREB1,MTPN,PACS2,KDM3B,MOB4,ZNF84,BAZ2A,ZNF512,PRKRA,ZFAND5,PATL1,ANKRD10,MTMR3,HGS,RBM25,HNRNPR,VPS26B,HNRNPH3,SAFB,LUC7L3,U2SURP,CNOT6,ZMIZ1,BRD9,AAAS |
| 2.014e-04 | -8.51 | GSE13547_2H_VS_12_H_ANTI_IGM_STIM_BCELL_UP | MSigDB lists | GSE13547_2H_VS_12_H_ANTI_IGM_STIM_BCELL_UP | 166 | 43 | 17377 | 2626 |
PTMS,GXYLT1,CLSPN,PTTG1,ANK3,CENPF,TPX2,CDCA3,CDCA8,NUF2,NCAPG,STMN1,TCF19,LCLAT1,SRXN1,DST,CCNA2,KIF14,PRC1,KIF22,KNTC1,MYBL1,TACC3,ASPM,PBK,KIF15,MKI67,RRM2,CKAP2L,ANLN,CCNF,SHCBP1,KIF11,RAD54B,OPTN,BIRC5,NEIL3,CEP55,HMGB2,SPCS3,TFDP2,EHD4,CCNB2 |
| 2.018e-04 | -8.51 | SIRNA_EIF4GI_UP | MSigDB lists | SIRNA_EIF4GI_UP | 89 | 27 | 17377 | 2626 |
CPNE1,ST13,NQO1,LAP3,EID1,BTG2,LETMD1,FRAT2,ASAH1,ADSL,GLUD1,ESYT1,SLC25A5,MATR3,CSDE1,KIF2A,EIF3K,HLA-B,ATP1A1,THADA,QARS,MPV17,HADHB,DTX4,NDUFS8,PSAP,HTRA2 |
| 2.022e-04 | -8.51 | ATP5F1B (ATP synthase F1 subunit beta) | protein interactions | 506 | 179 | 48 | 17029 | 2761 |
RPS2,CYLD,NDUFS1,SUZ12,MDH2,S1PR2,ATP6V1B2,ATP5PF,CDC73,ATPAF1,HNRNPA2B1,PA2G4,NDUFA2,HUWE1,PIN1,GRSF1,ZNF746,ZFYVE27,NDUFB9,TAGLN2,ATF2,ATP6V0D1,EIF5A,STAU1,ATP5IF1,TK1,PPT1,CUL3,VDAC2,LNX2,ADRB2,ATP5MF,VDAC1,MCM2,NCDN,ISG15,MAPK3,CAND1,SDHB,ATP5MC3,ATP6V0C,MBOAT1,FUS,ATP5F1A,B4GALT3,CDK2,IPO4,TUBB |
| 2.023e-04 | -8.51 | RBM28 (RNA binding motif protein 28) | protein interactions | 55131 | 75 | 25 | 17029 | 2761 |
NOL12,NIFK,STAU1,NOP2,RRP15,MECP2,RPL8,CUL3,DHX8,CUL1,BRCA1,KIF11,MAK16,RBM4,CAND1,DGCR8,NIP7,RPS14,RBM34,ZNF746,CTPS1,ZC3H3,ZC3HAV1,IFI16,GPATCH4 |
| 2.023e-04 | -8.51 | DHX8 (DEAH-box helicase 8) | protein interactions | 1659 | 75 | 25 | 17029 | 2761 |
CDC40,ZCCHC10,NOP2,THOC1,CHERP,XAB2,PPIE,CRNKL1,CUL3,DHX8,RPL15,JMJD6,CAND1,SMAD2,RPL32,MFAP1,AQR,POLR1B,AHCYL1,NKAPD1,FTSJ3,IFI16,CDC5L,PRPF19,SRPK2 |
| 2.023e-04 | -8.51 | FADD (Fas associated via death domain) | protein interactions | 8772 | 75 | 25 | 17029 | 2761 |
MOB4,RHOA,TNFAIP3,DDX24,NACA,ANK3,CUL3,EZR,CSNK1A1,PARK7,FADD,CFLAR,MBD4,FAS,DAP3,RAP1A,PIN1,STAT1,DAPK1,NAXE,MAVS,ABCA1,HIPK3,FAF1,RYBP |
| 2.023e-04 | -8.51 | PAFAH1B1 (platelet activating factor acetylhydrolase 1b regulatory subunit 1) | protein interactions | 5048 | 75 | 25 | 17029 | 2761 |
GID8,KARS,HSPH1,MAPRE2,MAPRE1,TCTEX1D2,DYNLL1,UBXN1,DCTN2,CSNK2A1,BICD2,WDR5,CHMP2B,ISG15,CAPN2,ATIC,NDE1,EIF5,TATDN1,CDK2,YWHAH,CHID1,NUDC,DCTN1,CSTF1 |
| 2.023e-04 | -8.51 | Cd2ap (CD2-associated protein) | protein interactions | 12488 | 75 | 25 | 17029 | 2761 |
USP7,CHMP2A,PDCD6IP,ERLIN1,RPL6,FLOT1,ATP6V0A1,KIF23,RACGAP1,CAPZA2,ATP6V1B2,CHMP2B,SHCBP1,ERC1,DAPK3,KEAP1,PRDX3,CAPZA1,ARAP1,CHMP4B,NDUFS5,CLTB,LRRC59,ATP6V0D1,MICAL3 |
| 2.034e-04 | -8.50 | MAPK8 (mitogen-activated protein kinase 8) | protein interactions | 5599 | 203 | 53 | 17029 | 2761 |
SH2D3A,SCOC,RPLP2,RAF1,TKT,IRF3,BCL2L1,DUSP22,MAPK14,APP,EEF2K,CDKN2C,RB1,PSMD2,APLP2,NFATC3,SHC1,CDC42,DCP1A,CDKN1B,BCL2,RBM15,ATF2,STAT3,PDPK1,CCT2,RHOA,PRKDC,EZR,GORASP2,NFATC2,PKMYT1,ELK1,MAP2K2,CCT8,FADD,MAPK3,FAS,GEMIN5,MAP3K4,SH3BP5,SMAD2,RAD18,GPS2,PIAS2,H2AFX,ATE1,YWHAZ,WDR62,MAPK1,NKAPD1,HRAS,CDKN2A |
| 2.037e-04 | -8.50 | Removal of licensing factors from origins | REACTOME pathways | R-HSA-69300 | 74 | 25 | 10287 | 1696 |
MCM10,PSMA8,CDT1,PSMB7,PSMA1,CDC6,ORC1,MCM2,PSMD9,PSMB9,PSMB3,PSMC4,RB1,PSMD2,PSMA6,CCNA2,PSMD1,RPS27A,PSMD8,PSMD3,MCM5,CDKN1B,ORC3,CDK2,PSMC1 |
| 2.042e-04 | -8.50 | Transport of the SLBP Dependant Mature mRNA | REACTOME pathways | R-HSA-159230 | 35 | 15 | 10287 | 1696 |
NDC1,NUP188,NUP210,RAE1,NUP107,NUP54,SLBP,NUP62,NUP155,NUP153,NUP85,NUP58,AAAS,NUP205,SEH1L |
| 2.050e-04 | -8.49 | REACTOME_MITOTIC_PROMETAPHASE | MSigDB lists | REACTOME_MITOTIC_PROMETAPHASE | 80 | 25 | 17377 | 2626 |
PLK1,MAPRE1,TAOK1,CDCA8,RANGAP1,NUF2,KIF2C,AURKB,PMF1,MIS12,PPP2CA,KIF2A,SMC3,AHCTF1,KIF18A,PPP2R5A,DSN1,BIRC5,NUP107,KNTC1,CENPT,CENPM,NUP85,SEH1L,NUDC |
| 2.062e-04 | -8.49 | BOUDOUKHA_BOUND_BY_IGF2BP2 | MSigDB lists | BOUDOUKHA_BOUND_BY_IGF2BP2 | 103 | 30 | 17377 | 2626 |
RPS15,PSRC1,SEC61B,ZDHHC8,DYNLL1,NACA,RPS10,TMEM147,WDR5,MAP1LC3B,PCBP1,HSPA1B,RPL36,NAPG,UAP1,RPS27A,FAM89B,COX8A,ATP6V0C,FAM126A,MARCH2,FAU,DNAJC30,CD81,ZMAT3,TSPAN5,S100A6,HIGD2A,VPS29,SRSF10 |
| 2.082e-04 | -8.48 | WDR5 (WD repeat domain 5) | protein interactions | 11091 | 165 | 45 | 17029 | 2761 |
PDCD6IP,MAX,CYLD,CXXC1,CUL1,KIF23,RACGAP1,KIF2C,ATP6V1B2,PAGR1,APP,SAC3D1,PRNP,WWP2,TERF2IP,DTL,USF1,ZNF335,PRC1,KANSL2,MAVS,CARM1,TERF2,SRPK2,RYBP,PDPK1,KAT2A,HARS,CUL3,PCGF6,WDR82,BRCA1,KMT2C,KDM1B,MEN1,CAND1,MBIP,EIF2D,CEP55,ARNTL,WDR59,PML,KMT2B,SGF29,HDAC2 |
| 2.086e-04 | -8.47 | SSB (Sjogren syndrome antigen B) | protein interactions | 6741 | 101 | 31 | 17029 | 2761 |
KARS,NIFK,CYLD,EWSR1,SUZ12,TRMT6,XIAP,CUL3,MYH9,CUL1,CSNK2A1,BRCA1,VDAC1,SAFB2,PMVK,APP,NPLOC4,CAND1,PPP2CA,SMC3,CCNA2,POLE,HUWE1,RBM34,H2AFX,ANP32A,TARDBP,CDK2,SMURF1,ABI1,CDC37 |
| 2.092e-04 | -8.47 | DBF4 (DBF4 zinc finger) | protein interactions | 10926 | 25 | 12 | 17029 | 2761 |
RAD18,DBF4,LSM8,BRCA1,ORC1,CHEK2,MCM2,HDGFL2,MEN1,ORC3,CDK2,CHAF1A |
| 2.099e-04 | -8.47 | negative regulation of protein modification process | biological process | GO:0031400 | 604 | 124 | 17256 | 2622 |
ZBED3,FGFR1OP,PPP1R37,ASH1L,GGNBP2,TSC2,FOXM1,NF1,FAM129A,PPP1R15B,ENSA,SIRT2,CCNB1,PPP1R16B,LYN,DUSP22,PARK7,PRNP,RPL11,TERF2IP,CDK5,CALM2,CDKN2C,PIN1,PPME1,PIK3R2,NOC2L,SOCS6,CDKN1B,CRY2,TARDBP,GPD1L,STRAP,DNMT1,CTDSP2,CHP1,PLK1,SNX25,BAK1,NCK1,PBK,GMFB,EZR,LRP5,DNAJA1,BRCA1,SOX4,EIF3A,SOCS7,PPP2CA,HHEX,DNAJC10,CORO1C,LIMK1,STK38,GADD45B,SOCS4,OGT,DVL1,ROCK1,PPP5C,ARRB2,SMAD4,HDAC2,PARD3,PDCD4,HSPH1,PPP1R2,TRIP12,GMFG,MECP2,UBXN1,PRKAA1,CIB1,AKT1S1,RGS2,PSEN1,VPS25,HMG20A,MAD2L2,FBXO5,PTPN2,FKBP1A,TFAP4,RB1,PTEN,PPP1R8,FBXO7,DUS2,H2AFY,MVP,GNAI2,SOCS5,PDPK1,TGFB1,PPP1R9B,TNFAIP3,ZMYND11,PRKDC,OXR1,GTPBP4,PRKAR1B,GBA,MEN1,KDM3A,ISG15,HSPA1B,MASTL,LEMD2,SH3BP5,MBIP,PLAA,GPS2,DUSP3,CSK,QARS,PPP1R11,NUP62,CABIN1,NR2F2,PARP10,IGBP1,HIPK3,CDKN2A |
| 2.101e-04 | -8.47 | Regulation of HSF1-mediated heat shock response | REACTOME pathways | R-HSA-3371453 | 70 | 24 | 10287 | 1696 |
DNAJC2,HSPH1,NDC1,NUP188,ST13,RAE1,NUP54,NUP155,DNAJB1,NUP205,HSPA1B,MAPK3,RPA1,RPA2,NUP210,HSPA4,NUP107,NUP62,NUP153,MAPK1,NUP85,NUP58,AAAS,SEH1L |
| 2.104e-04 | -8.47 | SLX4 (SLX4 structure-specific endonuclease subunit) | protein interactions | 84464 | 43 | 17 | 17029 | 2761 |
GID8,PLK1,ERCC1,NUP188,SUMO2,TEX10,LRRC1,UBE2I,APP,RPA1,TERF2IP,KPNA1,PCNA,MSH2,DDB1,MSH6,TERF2 |
| 2.104e-04 | -8.47 | COPZ1 (coatomer protein complex subunit zeta 1) | protein interactions | 22818 | 43 | 17 | 17029 | 2761 |
STAU1,SARNP,COPA,GOPC,SF3B1,KLC1,SEPT7,RUFY1,SCYL2,APP,COPG2,COPB2,SH3GLB1,CDK5,SUB1,TMED10,ZC3HAV1 |
| 2.104e-04 | -8.47 | TCP10L (t-complex 10 like) | protein interactions | 140290 | 43 | 17 | 17029 | 2761 |
GCC2,MAX,PPP1R21,CENPF,KIF2C,PMF1,BICD2,MXD4,APP,BTBD1,DAPK3,HOMER1,FBXO28,GRIPAP1,CCDC6,NDE1,SNAPIN |
| 2.104e-04 | -8.47 | MARCKSL1 (MARCKS like 1) | protein interactions | 65108 | 43 | 17 | 17029 | 2761 |
BCCIP,EWSR1,DCTN2,TMEM216,TOP3A,ATP6V0A1,MRPL16,BRCA1,MAPK14,RMI1,NMT2,ATP6V1D,RALB,KBTBD7,ATP6V0A2,CDK2,MRM3 |
| 2.118e-04 | -8.46 | GO_ORGANELLE_TRANSPORT_ALONG_MICROTUBULE | MSigDB lists | GO_ORGANELLE_TRANSPORT_ALONG_MICROTUBULE | 54 | 19 | 17377 | 2626 |
KIF3B,AP3M2,KIF23,RAB6A,WDR81,BICD2,RAB1A,RHOT1,AP3S1,RHOT2,TMEM201,KIF5B,CDC42,AP3S2,LRPPRC,KIFAP3,NDE1,CLN3,SNAPIN |
| 2.119e-04 | -8.46 | THUM_SYSTOLIC_HEART_FAILURE_DN | MSigDB lists | THUM_SYSTOLIC_HEART_FAILURE_DN | 207 | 51 | 17377 | 2626 |
RORB,HIVEP3,ZNF207,NDUFA5,COX15,FAM208B,PNISR,PPP1R2,UBN1,FAM129A,ANK3,VTI1A,EPN1,B4GALT1,AGPAT3,CYCS,CSNK1A1,CFLAR,MBD4,SLC25A36,PRNP,STRBP,PTEN,SRSF4,TTC3,UBE3C,RBM15,PCBP2,ZNF189,USP34,TXNL1,MLEC,TACC1,ELL2,DENND1B,MAP4K4,NLN,SEPT7,PRKRA,TANC1,RHOT1,ARMC8,RAB18,GOLGA4,NEK1,BBX,TRIM52,CHPT1,PDLIM5,SMAD4,N4BP2L2 |
| 2.123e-04 | -8.46 | GO_BAF_TYPE_COMPLEX | MSigDB lists | GO_BAF_TYPE_COMPLEX | 23 | 11 | 17377 | 2626 |
PHF10,RB1,ARID2,BRD7,SMARCA4,SS18L1,PBRM1,ARID1A,SMARCE1,ARID1B,SMARCD1 |
| 2.123e-04 | -8.46 | REACTOME_G0_AND_EARLY_G1 | MSigDB lists | REACTOME_G0_AND_EARLY_G1 | 23 | 11 | 17377 | 2626 |
LIN9,PCNA,CCNA2,RBL1,E2F4,TFDP1,MYBL2,E2F1,CDC6,RBBP4,CDK2 |
| 2.123e-04 | -8.46 | MODULE_196 | MSigDB lists | MODULE_196 | 23 | 11 | 17377 | 2626 |
KIF3B,MAPRE1,DYNLL1,KIF14,DCTN2,KIF23,KIF2C,ADRB2,STMN1,KIF11,DYNC1LI2 |
| 2.125e-04 | -8.46 | PPAN (peter pan homolog (Drosophila)) | protein interactions | 56342 | 88 | 28 | 17029 | 2761 |
STAU1,ZNF496,RRP15,DDX24,SF3B1,ZNF574,GTPBP4,CUL1,CSNK2A1,BRIX1,APP,CAND1,KRR1,UTP25,RB1,DDX56,ZNF317,MDM2,UPF1,STRBP,NVL,PPM1G,MRPL13,ZNF770,MRPL3,SMNDC1,IFI16,ZBTB24 |
| 2.125e-04 | -8.46 | EIF4B (eukaryotic translation initiation factor 4B) | protein interactions | 1975 | 88 | 28 | 17029 | 2761 |
USP7,RPL29,CYLD,CUL3,MYH9,CSNK2A1,XPO7,DDX39A,EIF4G2,EIF3A,XRCC5,EIF4A3,AHSA1,KBTBD7,NUP107,CTPS1,KHSRP,NUP153,YWHAZ,CDC25B,USP11,ARRB2,SMURF1,POT1,TERF1,PABPC1,CFL1,SRPK2 |
| 2.126e-04 | -8.46 | antigen processing and presentation of exogenous peptide antigen via MHC class II | biological process | GO:0019886 | 98 | 29 | 17256 | 2622 |
KIF3B,RAB7A,DYNLL1,DCTN2,KIF15,KLC1,KIF23,RACGAP1,ARF1,KIF2C,CAPZA2,AP1B1,KIF11,KIF2A,CTSL,SEC31A,CTSS,KIF18A,SEC24C,CAPZA1,DNM2,AP1M1,AP1S1,AP2B1,KIFAP3,KIF22,AP2S1,DYNC1LI2,DCTN1 |
| 2.143e-04 | -8.45 | CONCANNON_APOPTOSIS_BY_EPOXOMICIN_UP | MSigDB lists | CONCANNON_APOPTOSIS_BY_EPOXOMICIN_UP | 233 | 56 | 17377 | 2626 |
HSPH1,DNAJC2,GCLM,NQO1,KLHL21,DNAJB2,GADD45G,JMJD6,DNAJB1,MAP1LC3B,GLRX3,LMNA,MXD1,CREM,RAB21,RRN3,MDM2,PSMD1,PHTF1,NSFL1C,TNPO2,ARHGEF2,CYB5R1,MAP3K14,CLTB,EIF5,ORC3,PHKG2,CAMK2G,BAK1,IFRD1,ELL2,NQO2,KIAA0930,KCTD20,RIT1,ICAM2,STX16,KLF6,CDK11A,ZFR,HSPA1B,FAS,EPB41,PLD3,NUCB1,DAP3,HSPA4,IDE,SPATA2,DUSP3,CAPN7,CEBPG,CLU,TMEM159,N4BP2L2 |
| 2.151e-04 | -8.44 | ANAPC11 (anaphase promoting complex subunit 11) | protein interactions | 51529 | 32 | 14 | 17029 | 2761 |
UBE2D3,CDC16,CCNA2,CDC27,PTTG1,E2F1,NKD2,ANAPC2,CDC23,CCNB1,UBE2C,TRIM65,ANAPC4,FBXO5 |
| 2.151e-04 | -8.44 | SRSF8 (serine and arginine rich splicing factor 8) | protein interactions | 10929 | 32 | 14 | 17029 | 2761 |
CLK3,SUZ12,MECP2,SREK1,YWHAZ,SNRNP70,LUC7L,CD81,YWHAH,NKAPD1,PIP4K2A,APP,LUC7L2,SRPK2 |
| 2.151e-04 | -8.44 | Cul4a (cullin 4A) | protein interactions | 99375 | 32 | 14 | 17029 | 2761 |
DTL,UBTF,COPS8,BRWD1,RBX1,DDA1,DCAF11,COPS6,BRWD3,H2AFV,CHD1,DDB1,MLST8,CAND1 |
| 2.156e-04 | -8.44 | vesicle coat | cellular component | GO:0030120 | 55 | 19 | 18223 | 2701 |
TMED7,COPA,COPE,SCYL1,TMED3,PEF1,SYNRG,COPG2,PICALM,COPB2,NECAP2,SEC31A,PDCD6,SAR1A,SEC24C,AP2B1,AP1S1,CLTB,AP2S1 |
| 2.160e-04 | -8.44 | replisome | cellular component | GO:0030894 | 27 | 12 | 18223 | 2701 |
POLA2,RPA2,PCNA,PRIM2,TONSL,HELB,XPA,PURA,PRIM1,CDC5L,RPA1,PRPF19 |
| 2.175e-04 | -8.43 | BIOCARTA_BCR_PATHWAY | MSigDB lists | BIOCARTA_BCR_PATHWAY | 34 | 14 | 17377 | 2626 |
CALM2,VAV1,PPP3CA,NFATC3,SHC1,RAF1,RAC1,NFATC2,PPP3CB,ELK1,LYN,MAPK14,HRAS,MAPK3 |
| 2.175e-04 | -8.43 | PID_MAPK_TRK_PATHWAY | MSigDB lists | PID_MAPK_TRK_PATHWAY | 34 | 14 | 17377 | 2626 |
CDK5,RAP1A,NRAS,RPS6KA1,RAF1,KRAS,RIT1,CREB1,ELK1,EHD4,MAPK1,MAPK14,HRAS,MAPK3 |
| 2.175e-04 | -8.43 | LOPEZ_TRANSLATION_VIA_FN1_SIGNALING | MSigDB lists | LOPEZ_TRANSLATION_VIA_FN1_SIGNALING | 34 | 14 | 17377 | 2626 |
RBM25,EIF3D,TRIO,SH3GLB2,ILF3,TNPO3,ANP32A,MCL1,SOX4,PPP5C,STX16,DAPK3,SRPK2,GTF2F1 |
| 2.177e-04 | -8.43 | GO_IDENTICAL_PROTEIN_BINDING | MSigDB lists | GO_IDENTICAL_PROTEIN_BINDING | 1152 | 217 | 17377 | 2626 |
SRM,FGFR1OP,MAX,PDCD6IP,ST13,ADD1,TSC2,ADAM10,HEXB,TAP1,DHX8,GLUD1,ABCB10,OAT,PARK7,EDC3,PRNP,DST,USF1,PCNA,CDC42,GOT2,ZNHIT6,IL6ST,SRI,NUP153,CISD2,FGFR1OP2,CARM1,BAK1,TRIM8,TMEM115,SNRNP200,MCL1,PRKRA,ODC1,LUC7L,CHAF1A,OPTN,HHEX,WAS,SMAD2,RAD18,AXIN1,ACTB,SMG9,CHEK2,DVL1,SMAD1,DDX58,EWSR1,HJURP,CENPF,KCTD17,B4GALT1,EPHX2,VPS25,CHKA,TFAP4,RB1,MLX,ATIC,BANF1,XPA,MSH2,DAPK1,TIMELESS,ORAI1,TNPO3,BCL2,AHCY,GLE1,MCPH1,ALDH9A1,TERF2,FTL,GCC2,LDB1,PIP4K2C,EIF2AK1,UHRF1BP1,ADRB2,SEPT7,FXR1,APPL1,ZNF174,DAPK3,FAS,CAT,MBIP,PCM1,UAP1,CSK,DCK,PRPS2,TYW5,CEBPG,SLC16A1,YWHAZ,RUVBL2,MAP3K5,NDE1,NRBP1,ALS2,TCF12,DNMT3A,ATXN3,GNPNAT1,UGP2,NQO1,TRIP10,RAF1,SLC2A1,SLC39A13,MYH9,IRF3,BCL2L1,SAFB2,APP,EXT2,PHC2,APLP2,PDK2,NRF1,MDM2,SP100,TBC1D22A,SIAH1,BRI3,TARDBP,CORO1A,TP53BP2,CLN6,GPD1L,DVL2,PRPF19,SNX8,CPNE1,CLCN3,UBQLN4,CPOX,CUL3,ATXN1,PRPF3,MEF2D,CADM1,POLG2,PON2,IDE,CHMP4A,DGCR8,STAT6,STAT1,CHMP4B,ATF6,SCARB1,PDXK,PPP5C,MAPK1,COIL,SMAD4,POU3F2,MCM10,ANXA6,CASP6,TCF3,MRI1,TKT,BRAP,CBLL1,SUMF1,JMJD6,MYO9B,ETS1,TFRC,WRNIP1,SPPL2A,PDCD10,PTEN,PRC1,DCP1A,ABCD1,CREB1,STAT3,TPCN1,CAMK2G,S100A6,IMPA2,MSH6,LDHB,TGFB1,TK1,SNX2,LDHA,PRMT2,SPPL2B,TARS,PRDX1,SH3GLB1,FADD,CBX3,TPD52L2,PDCD6,PRDX3,BIRC5,PML,ACAT1,PKD2,SSNA1,MRFAP1L1,ACADM,NR2F2,USF2,TERF1,SSSCA1,IFI16,ESYT2 |
| 2.178e-04 | -8.43 | IRE1alpha activates chaperones | REACTOME pathways | R-HSA-381070 | 58 | 21 | 10287 | 1696 |
SEC61B,ADD1,SEC61G,CXXC1,SYVN1,SERP1,LMNA,DNAJB9,SSR1,YIF1A,SEC31A,SHC1,SEC61A1,TATDN2,ASNA1,MYDGF,PDIA6,CTDSP2,ATP6V0D1,PREB,DCTN1 |
| 2.198e-04 | -8.42 | SETDB1 (SET domain bifurcated 1) | protein interactions | 9869 | 142 | 40 | 17029 | 2761 |
POLA2,MBD1,DNMT3A,SUCLG1,SUZ12,DAP,SUMO2,ASAH1,UBE2I,BRIX1,PABPC4,ERH,MDM2,PCNA,PPP1R8,TARDBP,PCYT2,PHKG2,PPA1,LUC7L2,MOB4,ORAI2,PHF10,ZFP64,TK1,FAM118B,AKT2,VHL,PRKRA,TOLLIP,TRIM28,CHAF1A,GPS2,EXOC4,PML,USP11,C11orf1,MZT2B,TOB1,HDAC2 |
| 2.215e-04 | -8.41 | ERBB3 (erb-b2 receptor tyrosine kinase 3) | protein interactions | 2065 | 194 | 51 | 17029 | 2761 |
ZNF207,HNRNPAB,UQCR10,RAE1,VAV2,MRPS26,EPN1,HLA-A,SSR1,CRKL,CDK5,HNRNPA2B1,VAV1,ABL2,RPN1,PA2G4,SLC31A1,TNS3,MDM2,SHC1,PTEN,IL6ST,PIK3R2,PTPN11,MRPS27,PTGES3,ILKAP,SRPK2,CDC37,NCK1,HNRNPF,TUFM,MTMR6,DNAJA1,PCGF1,SLC25A5,MRPS14,HLA-B,PON2,HGS,CSK,RPS27A,HNRNPH3,PTPN7,LRPPRC,UQCRH,ACTB,ATP5F1A,PTPDC1,TUBB,PDF |
| 2.217e-04 | -8.41 | Hepatitis B | KEGG pathways | hsa05161 | 144 | 40 | 7161 | 1149 |
DDX58,RAF1,CYCS,IRF3,RB1,NFATC3,PCNA,CCNA2,PTEN,PIK3R2,CDKN1B,BCL2,MAVS,CREB1,ATF2,STAT3,TGFB1,NRAS,AKT2,E2F3,KRAS,NFATC2,ELK1,MAP2K2,FADD,MAPK3,FAS,JAK1,BIRC5,STAT6,E2F1,STAT1,YWHAZ,TICAM1,MAPK1,E2F2,CDK2,HRAS,SMAD4,DDB1 |
| 2.220e-04 | -8.41 | VPS51 (VPS51, GARP complex subunit) | protein interactions | 738 | 47 | 18 | 17029 | 2761 |
YTHDC1,CCDC93,RPRD1A,RCOR1,RAB1A,PSMD9,GIT2,HMG20A,OIP5,ETS2,GRIPAP1,RABGAP1L,SNAP29,ARNTL,EXOC4,CDK12,NUDT3,CDC5L |
| 2.220e-04 | -8.41 | EIF2S3 (eukaryotic translation initiation factor 2 subunit gamma) | protein interactions | 1968 | 47 | 18 | 17029 | 2761 |
UNK,CYLD,ABCF2,CTCF,DNAJA1,EIF1B,CDC73,CAND1,SUB1,PLD3,EIF2S2,C1orf131,QARS,MAPK6,TARDBP,POLR1B,H3F3A,CDK2 |
| 2.220e-04 | -8.41 | UBL7 (ubiquitin like 7) | protein interactions | 84993 | 47 | 18 | 17029 | 2761 |
ERCC1,UBE4B,DCUN1D5,UBQLN2,TWF2,RAD23A,UPF1,RAD23B,TTC9C,CAPN7,IMPDH1,ZRANB2,AHCYL1,CDKN2A,SSSCA1,VPS29,KDELR1,USP34 |
| 2.220e-04 | -8.41 | ZNF169 (zinc finger protein 169) | protein interactions | 169841 | 47 | 18 | 17029 | 2761 |
USP7,TRIM41,RPS15,ZBTB10,ZNF445,ZNF316,TWNK,ZNF121,ZFR,ZNF92,TRIM26,SYNCRIP,STRBP,LTBP4,HNRNPR,ZNF689,ZNF45,ZBTB24 |
| 2.220e-04 | -8.41 | ACAD11 (acyl-CoA dehydrogenase family member 11) | protein interactions | 84129 | 47 | 18 | 17029 | 2761 |
CNTN5,TRAFD1,GPBP1L1,DCAF8,ZMYM5,KCTD17,MIER2,APP,SDHB,PEX5,MTMR4,NSFL1C,PTPN7,GTSE1,TTC4,PPP6R2,PPP6R3,PPP6R1 |
| 2.220e-04 | -8.41 | RASSF8 (Ras association domain family member 8) | protein interactions | 11228 | 47 | 18 | 17029 | 2761 |
POC1A,KLC1,NLN,RAB3IP,LYN,APP,ANKRD28,PCM1,TIMM13,GOLGA2,FAAP100,ZNF639,CORO1A,TP53BP2,TCOF1,PARP10,YWHAH,PARD3 |
| 2.220e-04 | -8.41 | PPP1R3A (protein phosphatase 1 regulatory subunit 3A) | protein interactions | 5506 | 47 | 18 | 17029 | 2761 |
RPAP3,SHOC2,PPP1R9B,PPP1R18,PPP1R2,RPS6KA1,MKI67,WDR82,CDCA2,PPP3CB,BRCA1,ERBIN,KIF18A,PDRG1,PPP1R8,PPP1R11,TP53BP2,RUVBL2 |
| 2.220e-04 | -8.41 | GO_MITOTIC_SPINDLE | MSigDB lists | GO_MITOTIC_SPINDLE | 50 | 18 | 17377 | 2626 |
PKP4,KAT2A,ASPM,DYNLL1,KIF23,RACGAP1,RANGAP1,SIRT2,SPAG5,KIF18A,GOLGA2,CDC42,MAP4,FAM83D,PKD2,KIF22,MAPK1,ESPL1 |
| 2.224e-04 | -8.41 | GSE25890_CTRL_VS_IL33_IL7_TREATED_NUOCYTES_DN | MSigDB lists | GSE25890_CTRL_VS_IL33_IL7_TREATED_NUOCYTES_DN | 192 | 48 | 17377 | 2626 |
GCLM,GXYLT1,SUCLG1,CASP6,HNRNPUL2,ANKH,YTHDC2,XIAP,AGFG1,CCNL2,COMMD8,PAIP1,NDUFS4,PRNP,LIN9,CCP110,CENPJ,GEMIN6,NAP1L4,ZRANB1,PHKG2,TACC3,SAP30,CDC5L,ACSL5,TGFB1,PLK3,GTF3C6,CSRP1,HERPUD2,ARPC1A,GINS4,HSPA1B,PCM1,AHNAK,KIF18A,ORMDL2,AGPAT2,TTLL4,OSBPL8,STK38,TATDN2,ARNTL,AKNA,YY1,GPATCH4,ESYT2,CWC25 |
| 2.224e-04 | -8.41 | HALLMARK_HEME_METABOLISM | MSigDB lists | HALLMARK_HEME_METABOLISM | 192 | 48 | 17377 | 2626 |
GCLM,ADD1,CAST,PIGQ,UROD,SLC2A1,EZH1,XPO7,PSMD9,FOXO3,CCDC28A,TFRC,SLC25A37,RAD23A,ATG4A,LPIN2,FBXO7,TCEA1,MARCH2,RNF19A,MINPP1,HTRA2,MOSPD1,CLCN3,OSBP2,ELL2,NEK7,NUDT4,BTG2,CPOX,NARF,ATP6V0A1,FBXO9,HTATIP2,ARHGEF12,EIF2AK1,HAGH,PICALM,RBM38,OPTN,EPB41,CAT,VEZF1,CDC27,DCAF11,TFDP2,E2F2,TSPAN5 |
| 2.224e-04 | -8.41 | KAECH_NAIVE_VS_MEMORY_CD8_TCELL_DN | MSigDB lists | KAECH_NAIVE_VS_MEMORY_CD8_TCELL_DN | 192 | 48 | 17377 | 2626 |
TXN,MOGS,RACGAP1,HCFC1R1,STMN1,HLA-A,CAPN2,PCNA,SHC1,MBD2,RPAP1,BCL2,MDFIC,CLDND1,ST8SIA2,F2R,S100A6,LYPLA2,MAPRE2,POLR2L,KLF10,TNFAIP3,ELL2,TSPAN31,MAP7D1,PACS1,CYFIP2,KRTCAP2,VKORC1,ODC1,KLF6,XRCC5,MYO1F,NUCB1,SEPT1,AHNAK,TMED10,RBMX,GADD45B,ITGB1,ATF6,HMGB2,PGAM1,CHPT1,ZMAT3,TOB1,RAD51D,PFKP |
| 2.224e-04 | -8.41 | GSE42088_UNINF_VS_LEISHMANIA_INF_DC_4H_DN | MSigDB lists | GSE42088_UNINF_VS_LEISHMANIA_INF_DC_4H_DN | 192 | 48 | 17377 | 2626 |
USP7,CYTIP,RPLP2,TSC22D3,FAM53C,NACA,MAP1LC3B,PABPC4,RPL11,PRNP,CAPN2,ADD3,SP100,ARHGEF1,PPCDC,TIPARP,PCBP2,EEF1D,IFRD1,EIF3L,KLF10,BTG2,MAP4K4,RPL8,CIRBP,RPL38,RPS24,MTMR12,KCNQ1,SRSF5,ICAM2,RPL27A,SERP1,RPS9,EIF3H,RBM38,MTMR3,RPL37,RPL32,CLK3,QARS,RPS14,RPLP1,HMGB2,BTF3,KLHDC4,SRSF3,FAU |
| 2.224e-04 | -8.41 | GSE29164_CD8_TCELL_VS_CD8_TCELL_AND_IL12_TREATED_MELANOMA_DAY3_DN | MSigDB lists | GSE29164_CD8_TCELL_VS_CD8_TCELL_AND_IL12_TREATED_MELANOMA_DAY3_DN | 192 | 48 | 17377 | 2626 |
GCLM,CYTIP,STRN4,KLF13,KIF23,MYH9,ABHD14A,GART,UTP18,IL6ST,BTF3L4,ANP32A,KCNAB2,SMC4,ABCC5,SPTAN1,SHOC2,HMGN5,SIGMAR1,NSDHL,MAP4K4,ITM2A,LRRC8A,EMP3,GLO1,PLEC,RAB3IP,ADRB2,ICAM2,NDRG3,RBM38,CYB5A,FAS,UTP20,FBXO21,KPNA4,HSPB11,EIF4ENIF1,RBM25,PDLIM1,TULP3,COX8A,TRAF5,RPS26,SMAD4,GCSH,IPO4,TMEM131 |
| 2.224e-04 | -8.41 | HHV8GK18_gp82 (ORF72) | protein interactions | 4961471 | 10 | 7 | 17029 | 2761 |
CDK5,CDKN2C,CDKN1B,CDK2,CCT8,RAB7A,CDKN2A |
| 2.236e-04 | -8.41 | regulation of mRNA splicing, via spliceosome | biological process | GO:0048024 | 80 | 25 | 17256 | 2622 |
YTHDC1,RBM42,SRSF6,RBM8A,SMU1,RNPS1,SREK1,TIA1,JMJD6,THRAP3,RBM4,DDX17,HNRNPA2B1,RBM25,NSRP1,RBMX,SRSF4,TRA2B,DDX5,SRSF3,SNRNP70,SRSF10,PRPF19,SRPK2,RBM15B |
| 2.252e-04 | -8.40 | GSE42021_CD24HI_VS_CD24LOW_TREG_THYMUS_UP | MSigDB lists | GSE42021_CD24HI_VS_CD24LOW_TREG_THYMUS_UP | 187 | 47 | 17377 | 2626 |
TMEM106C,KIF3B,DNAJC2,LYRM4,THOC1,UBN1,URB2,GSPT2,KIAA0232,CTCF,FAM136A,POFUT1,POLR3K,WRB,MEAF6,SLC25A36,PIN1,PHTF1,MRPL34,GNAI2,FAM171A1,TERF2,WDR41,CDKN2AIP,HEMK1,ZNF84,OXR1,ZBED5,EMP3,THNSL1,ODC1,EPB41,UBTF,ALDH3B1,TBC1D17,CHMP4A,TFE3,HPS5,APPL2,MLYCD,MEGF9,KHSRP,NGLY1,RNF139,NUDT3,RAD51D,DDX42 |
| 2.252e-04 | -8.40 | GSE27786_NKTCELL_VS_ERYTHROBLAST_UP | MSigDB lists | GSE27786_NKTCELL_VS_ERYTHROBLAST_UP | 187 | 47 | 17377 | 2626 |
SEPHS2,NDUFV2,MRPL42,PHF23,PRKCSH,TOR3A,C19orf25,DHX9,CDK13,SIRT2,NHLRC3,MYO9B,IFT27,ZNF518A,EXT2,NDUFS7,RGS1,NDUFS4,THADA,TBC1D14,MECR,FOXN2,CLDND1,GM2A,TRIM14,CPNE1,DDX28,PGGT1B,ICMT,STX16,API5,TARS,PHF6,BBS12,NMT2,EIF3K,TMEM168,DDOST,ACYP1,ADAM9,CANT1,ZFP90,RUVBL2,ZMIZ1,CPEB2,CSNK1D,ZBTB24 |
| 2.252e-04 | -8.40 | GSE11924_TH1_VS_TH2_CD4_TCELL_UP | MSigDB lists | GSE11924_TH1_VS_TH2_CD4_TCELL_UP | 187 | 47 | 17377 | 2626 |
INTS2,SNX27,MRPS15,YTHDC2,PDCD7,CRLF3,GNB2,CHKA,CCNK,HOMER1,ZNF473,BRPF3,PPP1R8,RAD23B,NOC2L,AKR1B1,FNIP2,TAF5L,TAGLN2,NSUN4,PAQR6,CCT2,UBQLN4,PSRC1,TRIM8,KAT2A,MTA2,MFNG,SREK1,FRAT2,MRPL16,MEF2D,METTL22,ICAM2,ODC1,BRMS1,C1orf131,HSPBP1,CORO1C,TFDP1,PPA2,UHRF2,RNF38,PRMT7,PRPF4,GCSH,AAAS |
| 2.252e-04 | -8.40 | GSE36392_EOSINOPHIL_VS_NEUTROPHIL_IL25_TREATED_LUNG_DN | MSigDB lists | GSE36392_EOSINOPHIL_VS_NEUTROPHIL_IL25_TREATED_LUNG_DN | 187 | 47 | 17377 | 2626 |
TM9SF4,TRIP10,CDCA3,SMARCA4,GLUD1,TBC1D13,LANCL1,DUSP22,RCOR3,MYEF2,COPG2,APOPT1,DDRGK1,SNRNP25,PA2G4,HUWE1,DPYSL2,IL6ST,FIZ1,PRC1,TNPO3,YBX1,BCL2,CYC1,MVP,MCPH1,KCNAB2,FYTTD1,POLR2I,MLEC,IDH3A,UHRF1BP1,BORA,GFER,RAB22A,DTWD1,NSA2,MRPL2,DDOST,CORO1C,PRPS2,PIAS2,SCARB1,NDUFS5,PPP5C,MAPK1,GPATCH4 |
| 2.252e-04 | -8.40 | GSE45365_NK_CELL_VS_BCELL_MCMV_INFECTION_UP | MSigDB lists | GSE45365_NK_CELL_VS_BCELL_MCMV_INFECTION_UP | 187 | 47 | 17377 | 2626 |
SEPHS2,CHMP2A,GMFG,C1orf112,HEXB,SDC2,RACGAP1,AP3S1,WRB,HDDC2,PRNP,DECR1,ARPC5,CYB5R1,TECR,MRPL11,PDIA6,GPD1L,DNMT1,TMED2,PDLIM2,MOSPD1,FTL,ARHGAP17,MLEC,SEPT9,PPT1,KIAA0930,FRAT2,LLPH,TMEM147,PRKRA,RAB1A,SH3BP5,CAT,PCM1,OSBPL11,CCDC6,TULP3,ITGB1,CCDC69,PDXK,MAP3K5,HEXA,RTN3,BYSL,S100PBP |
| 2.252e-04 | -8.40 | GSE11864_CSF1_IFNG_VS_CSF1_IFNG_PAM3CYS_IN_MAC_UP | MSigDB lists | GSE11864_CSF1_IFNG_VS_CSF1_IFNG_PAM3CYS_IN_MAC_UP | 187 | 47 | 17377 | 2626 |
NSMCE4A,H2AFZ,CAST,EIF3D,RAC1,MRPS26,TMEM97,AP3S1,STMN1,TCF19,REEP5,GIT2,ATPAF1,DDRGK1,FAM192A,FKBP1A,CYHR1,GSTK1,RAP1A,EIF4A3,NT5DC1,TTC9C,PARL,AHCY,PLCL2,DNMT1,TRIM14,SAP30,SNX2,TIMMDC1,METTL5,LDHA,GLO1,ARHGDIB,ESYT1,ARHGAP15,MYO1F,ANKZF1,DNAJC10,ALDH3B1,ELMO1,ACLY,ZDHHC7,WDR76,REEP4,PGAM1,IFI16 |
| 2.252e-04 | -8.40 | GSE9988_ANTI_TREM1_AND_LPS_VS_VEHICLE_TREATED_MONOCYTES_DN | MSigDB lists | GSE9988_ANTI_TREM1_AND_LPS_VS_VEHICLE_TREATED_MONOCYTES_DN | 187 | 47 | 17377 | 2626 |
RHOG,KIF3B,CYTIP,HECA,ANKRD13D,KDM4A,PHF23,RPS6KA1,DYNLL1,SUMO2,RAC1,CCM2,KLF13,TWF2,PCBP1,SDHA,GNB2,GIT2,CAPZA1,FAM89B,CORO1A,ZNF710,GNAI2,TNRC18,DNAL4,PPP1R9B,PPP1R18,TRIM8,TACC1,ATG9A,EMP3,WDR82,MAP7D1,BUD13,PTTG1IP,IRF5,MYO1F,TFEB,DDX17,CSK,ZNF436,BAZ1B,STK11,PSAP,MAPK1,PURA,OAZ1 |
| 2.252e-04 | -8.40 | GSE20198_IL12_IL18_VS_IFNA_TREATED_ACT_CD4_TCELL_DN | MSigDB lists | GSE20198_IL12_IL18_VS_IFNA_TREATED_ACT_CD4_TCELL_DN | 187 | 47 | 17377 | 2626 |
HECA,PDCD6IP,GNPNAT1,ADAM10,PHF23,TRAK1,ALKBH5,MEF2A,ARGLU1,SLC25A44,QSOX2,CMTM6,PNO1,LMNA,NFATC3,CCNA2,IARS,CENPJ,NUP107,RNF19A,STAT3,HNRNPM,TACC3,SNX2,SIGMAR1,IDH3A,KIF15,CRNKL1,MIER2,GORAB,UTP3,MATR3,TSR2,EIF3G,PDCD6,JAK1,MAGT1,DCK,ACOX1,ARNTL,NUP62,CCDC59,C7orf26,IPO4,ATMIN,BYSL,NXT2 |
| 2.252e-04 | -8.40 | GSE17721_0.5H_VS_8H_CPG_BMDC_DN | MSigDB lists | GSE17721_0.5H_VS_8H_CPG_BMDC_DN | 187 | 47 | 17377 | 2626 |
AGRN,TM9SF4,HLA-E,FAM53C,FAM129A,TOR1AIP1,TAP1,NUP54,SIKE1,TBC1D13,CRLF3,FAM8A1,ARL6IP6,PHC2,UBXN2A,SLC31A1,CLIC4,C18orf32,PSMA6,MBD2,TNPO2,CREB1,TFG,MTPN,DRAM2,MOB4,ENPP4,ACP2,LAP3,DENND1B,LYRM1,CAMSAP1,ILF3,UHRF1BP1,DNAJA1,PITPNB,ASB13,PSMB9,RDH11,KRIT1,KPNA4,BRD2,DGCR8,CHMP4B,AKNA,USP53,ABCA1 |
| 2.252e-04 | -8.40 | GSE17721_LPS_VS_CPG_6H_BMDC_DN | MSigDB lists | GSE17721_LPS_VS_CPG_6H_BMDC_DN | 187 | 47 | 17377 | 2626 |
SEPHS2,SRM,RORB,THOC1,GNPDA1,RAF1,SRSF6,UFC1,COPE,HEXB,LAMTOR3,RACGAP1,PMVK,TFAP4,FLAD1,SEC11A,NOL11,INTS7,GOT2,NUP107,BTF3L4,DAPK1,RPAP1,MRPL40,ZNRD1,HDHD2,CCT2,NTPCR,EIF3L,FOPNL,HTATIP2,PSMG1,PACS1,NDUFA7,RHOT2,CCT8,TARS,TFEB,FAS,MKNK1,WAS,ATP6V1C1,UBE2C,PTDSS1,BYSL,VPS29,PDF |
| 2.252e-04 | -8.40 | GSE27786_LIN_NEG_VS_CD8_TCELL_DN | MSigDB lists | GSE27786_LIN_NEG_VS_CD8_TCELL_DN | 187 | 47 | 17377 | 2626 |
DDX58,TRIP12,RPLP2,PTTG1,BABAM1,AP3M2,MRPS26,TM9SF3,CSNK2A1,CHIC2,CCNL2,RLF,SLC20A1,ANKIB1,SF3B2,MDM2,NUP210,ARPC5,AKR1B1,ORAI1,ATP6V0A2,MCMBP,TNRC18,ARL5A,NSUN4,SMC4,CSNK1G2,RHOA,CIC,TAOK1,CUL3,ITM2A,KRAS,NFATC2,PLEC,ASB13,MARK2,EIF3K,PAF1,PDCD6,PDLIM1,RAB24,VPS26B,STAT1,NLRC5,PDLIM5,ZNF511 |
| 2.252e-04 | -8.40 | GSE22886_IGM_MEMORY_BCELL_VS_BM_PLASMA_CELL_DN | MSigDB lists | GSE22886_IGM_MEMORY_BCELL_VS_BM_PLASMA_CELL_DN | 187 | 47 | 17377 | 2626 |
SRM,LIME1,TM9SF4,UROD,COPE,HEXB,NENF,CLCC1,SLC35B1,FKBP2,REEP5,ABHD14A,LMNA,CFLAR,CDK5,CLIC4,DAD1,FUT8,UBA5,RRBP1,SLC38A10,CYB5R1,TECR,CITED2,GM2A,TMEM115,TIMP2,PIGT,ELL2,LAP3,NET1,SSR2,RAB1A,VKORC1,RHEB,NEU1,YIF1A,SERF2,UAP1,ERGIC3,SIL1,SPCS3,PDXK,COPS6,B4GALT3,EHD4,CHPF2 |
| 2.258e-04 | -8.40 | EDEM3 (ER degradation enhancing alpha-mannosidase like protein 3) | protein interactions | 80267 | 63 | 22 | 17029 | 2761 |
HSPH1,COPA,PRKCSH,ERLIN1,MOGS,TGOLN2,EDEM2,COPB2,SSR1,DNAJC10,RPN1,HSPBP1,PSMD1,DDOST,STT3A,LRPPRC,SEL1L,VCPIP1,RPN2,LMAN1,ECPAS,CDC37 |
| 2.258e-04 | -8.40 | AGO4 (argonaute 4, RISC catalytic component) | protein interactions | 192670 | 63 | 22 | 17029 | 2761 |
GALK1,RPL35,AGO2,TUFM,RPL38,SLC25A22,DNAJA1,RPL27A,SLC25A5,RPS9,APP,PABPC4,ARF4,PRDX1,RPL11,JAK1,YBX1,ACTB,PTGES3,RPS26,TUBB,SLC25A1 |
| 2.259e-04 | -8.40 | WDR1 (WD repeat domain 1) | protein interactions | 9948 | 97 | 30 | 17029 | 2761 |
EIF5A,USP7,PTMS,MAPRE1,TXN,BIRC3,TKT,CUL3,LDHA,EZR,MYH9,LACTB2,CAPZA2,ANLN,MAPK14,BIRC2,PABPC4,ISG15,CBX3,ADSS,KEAP1,UAP1,PPME1,MYO18A,NUP107,GPI,TALDO1,CDK2,CFL1,LDHB |
| 2.259e-04 | -8.40 | STK11 (serine/threonine kinase 11) | protein interactions | 6794 | 97 | 30 | 17029 | 2761 |
RPAP3,MOB4,MAPRE1,SEPT9,KDM4A,GNPDA1,PHF23,PRKAA1,KIF23,CSNK2A1,SMARCA4,PRKACA,MARK2,PIP4K2A,APP,WDR48,CALM2,PDXP,PLD3,PTEN,ABRAXAS2,H2AFX,CAB39,STK11,CRY2,FKBP5,USP11,DVL2,PARD3,CDC37 |
| 2.263e-04 | -8.39 | PHD | smart domains | SM00249 | 89 | 26 | 9493 | 1367 |
PHF10,ASH1L,KMT2E,BAZ2A,PHF23,KDM4A,SHPRH,PHRF1,CXXC1,ZMYND11,NSD3,DIDO1,KMT2C,TCF19,TRIM28,PHF6,SP100,BRPF3,KDM2A,CHD3,PHF14,UHRF2,KMT2B,BAZ1B,INTS12,FBXL19 |
| 2.269e-04 | -8.39 | DAZARD_UV_RESPONSE_CLUSTER_G6 | MSigDB lists | DAZARD_UV_RESPONSE_CLUSTER_G6 | 142 | 38 | 17377 | 2626 |
UBL3,PPP1R12A,MECP2,GNE,TMX4,STARD7,CUL1,KIF23,CCNB1,FOXO3,BIRC2,SLC25A36,RABGAP1L,MBD2,KIF14,ADCY9,ATP13A3,XPA,PIKFYVE,ATF2,LPCAT1,SMC4,VPS13B,SP3,SHOC2,TLK1,MKI67,SLBP,KIF11,KIF2A,BBX,MEGF9,RBPJ,MAP3K5,RRS1,ZMIZ1,CCNB2,ZNF146 |
| 2.269e-04 | -8.39 | REACTOME_PEPTIDE_CHAIN_ELONGATION | MSigDB lists | REACTOME_PEPTIDE_CHAIN_ELONGATION | 85 | 26 | 17377 | 2626 |
RPS15,RPL29,RPL35,RPS2,RPLP2,RPL8,RPS10,RPL6,RPL38,RPL15,RPS24,RPL27A,RPS9,RPSA,RPL11,RPL23A,RPL36,RPL37,RPL32,RPL17,RPS27A,RPS14,RPLP1,RPL19,FAU,RPS26 |
| 2.270e-04 | -8.39 | DAB2 (DAB2, clathrin adaptor protein) | protein interactions | 1601 | 84 | 27 | 17029 | 2761 |
HSPH1,MAPRE1,TRIO,MYH9,NUP155,CAPZA2,ANLN,ITGB5,APP,PICALM,PRDX1,HSPA1B,SF3B2,APLP2,SMAD2,CDC16,CSK,PIN1,AXIN1,MYO18A,GTSE1,AP2B1,AHCY,ACTB,DVL1,CLTB,DVL2 |
| 2.277e-04 | -8.39 | GSE10239_NAIVE_VS_KLRG1INT_EFF_CD8_TCELL_DN | MSigDB lists | GSE10239_NAIVE_VS_KLRG1INT_EFF_CD8_TCELL_DN | 182 | 46 | 17377 | 2626 |
POLA2,SKA3,GNPDA1,B4GALT5,DBF4,GTF3A,AP3S1,PSMD9,STMN1,HLA-A,FKBP1A,RFWD3,DECR1,CCNA2,SLC1A4,BANF1,PRC1,GEMIN6,YIF1B,KIF22,SGCB,TACC3,CYFIP1,MAPRE2,MLEC,NXT1,PBK,TBRG4,MRPS10,AURKB,ANLN,RFC2,KIF11,RHBDF2,AKAP1,ZMYM3,RAD51C,KIF18B,POLE,FAM110A,TATDN2,NAA20,EHD4,NDE1,PDSS2,LRP8 |
| 2.277e-04 | -8.39 | GSE3039_NKT_CELL_VS_ALPHABETA_CD8_TCELL_DN | MSigDB lists | GSE3039_NKT_CELL_VS_ALPHABETA_CD8_TCELL_DN | 182 | 46 | 17377 | 2626 |
PWWP2A,GLT8D1,PPCS,GNPNAT1,SCOC,SRSF6,TOR3A,MAGED1,AP3M2,CREBL2,B4GALT4,CSNK1A1,MIEN1,JMY,DDRGK1,CAPN2,SUB1,MRPL11,GTF2H2,CSNK1G3,PREB,ARHGAP17,BTAF1,GTPBP4,ATXN1,GORAB,NFATC2,GFER,MAK16,CCT8,ABCF1,ISG15,EIF3A,TWISTNB,SGSH,TMEM168,MAGT1,QARS,SNAP29,U2SURP,ATF6,SLC22A23,PURA,VPS29,RAB3IL1,ADAM23 |
| 2.277e-04 | -8.39 | GSE41867_LCMV_ARMSTRONG_VS_CLONE13_DAY8_EFFECTOR_CD8_TCELL_DN | MSigDB lists | GSE41867_LCMV_ARMSTRONG_VS_CLONE13_DAY8_EFFECTOR_CD8_TCELL_DN | 182 | 46 | 17377 | 2626 |
GALK1,FGFR1OP,SUCLG1,ARID2,UQCR10,CDK2AP2,LAGE3,MRPS26,ABHD14B,STMN1,RNF103,EEF2K,FASTKD3,ANKRD26,GOLM1,IRF4,PDXP,MTMR4,MTA1,TXLNA,YIF1B,CNOT6L,RPRD1B,GPX4,POLR2I,TSTA3,ELL2,AKT2,SNRPB,KIAA0930,RRM2,TMEM147,EAF2,KDM1B,ARL5B,NEU1,AKAP1,KPNA1,ETS2,VPS26B,ZRANB2,DVL1,MZT2B,ATP6V0E1,SLC25A39,GCSH |
| 2.277e-04 | -8.39 | GSE19198_CTRL_VS_IL21_TREATED_TCELL_6H_UP | MSigDB lists | GSE19198_CTRL_VS_IL21_TREATED_TCELL_6H_UP | 182 | 46 | 17377 | 2626 |
MIF,WASF2,SRM,GALK1,GMFG,THOC1,TRERF1,SUCLG1,DAP,SLC25A12,BZW2,NDUFV1,TBC1D14,RCSD1,SRI,BTF3L4,PARL,AFF1,AHCY,CORO1A,CYC1,MOB1A,GNAI2,PDLIM2,GINS1,BIRC3,CDC123,EMB,SELPLG,SLC16A7,SCFD2,OGDH,SLC25A5,NECAP2,SNAP23,DTD1,SCARB1,TRIM32,GPI,RBPJ,EHD4,IFI16,PDCD4,TUBB,IPO4,PFKP |
| 2.277e-04 | -8.39 | GSE29164_DAY3_VS_DAY7_UNTREATED_MELANOMA_DN | MSigDB lists | GSE29164_DAY3_VS_DAY7_UNTREATED_MELANOMA_DN | 182 | 46 | 17377 | 2626 |
GALK1,PARP12,ARID2,CDK2AP2,TOR3A,AGPAT3,SDF2L1,POMP,ZADH2,PSMA6,CS,CLCN6,CLDND1,OSTC,CTDSP2,PREB,SEPT9,DENND1B,RAB7A,PGS1,VDAC2,LRRC1,GALNT7,KRTCAP2,BBS12,KIF2A,NUCB1,SCARB2,C1orf131,MID1IP1,ORMDL2,TTLL4,TMED10,STT3A,ACYP1,HIPK2,QARS,MYO18A,SCARB1,GALNT10,RBPJ,SPCS3,CD81,NUMB,RHEBL1,PTOV1 |
| 2.277e-04 | -8.39 | GSE24726_WT_VS_E2-2_KO_PDC_DAY6_POST_DELETION_UP | MSigDB lists | GSE24726_WT_VS_E2-2_KO_PDC_DAY6_POST_DELETION_UP | 182 | 46 | 17377 | 2626 |
EXOC3,UBN1,CDT1,TMX4,RRAGC,LANCL1,NANS,CRLF3,PITHD1,HMG20A,SF3B2,LIN9,CAPN2,EFCAB11,GTSE1,CORO1A,CNOT6L,ZNF583,HP1BP3,NIPAL3,CCT2,GCC2,PPP3CA,ARHGAP17,RPL35,MAPRE2,PRIM2,MFNG,WDHD1,AURKB,RIT1,WDR81,WBP1,FXR1,MPG,SHCBP1,TRIM28,RPA1,AMZ2,BRMS1,EIF3K,RBL1,PRPS2,UHRF2,ATF6,ATP6V1C1 |
| 2.277e-04 | -8.39 | GSE14308_TH1_VS_INDUCED_TREG_DN | MSigDB lists | GSE14308_TH1_VS_INDUCED_TREG_DN | 182 | 46 | 17377 | 2626 |
RHOG,HNRNPAB,LUZP1,HJURP,DYNLL1,CHIC2,COX4I1,NANS,AP1B1,B4GALT4,MIEN1,RPAIN,CFLAR,TMCC3,ASPHD2,SEC11A,FARSA,LRRC8D,BUD31,BTF3L4,MECR,RPL19,UBE3B,MCPH1,NAGPA,NASP,SEPT9,SIGMAR1,VHL,PPP1R21,SEPT8,DDX20,MBD3,HAUS8,INF2,CORO1C,ACLY,WDR7,GLG1,FAM126A,SMPD4,PPP6R2,RRS1,RBBP4,MAPK1,PDSS2 |
| 2.278e-04 | -8.39 | FOXB1 (forkhead box B1) | protein interactions | 27023 | 133 | 38 | 17029 | 2761 |
NDUFV2,COPA,SF3B1,CHD1L,HNRNPUL2,UBE4A,XPO7,NUP205,RPA2,MRPL50,PA2G4,SMC3,IARS,HUWE1,NOC2L,H2AFY,EEF1D,SMC4,LARS,NSDHL,BTAF1,SUGP2,RANGAP1,SMC2,TOMM40,MEN1,DDX39A,SYMPK,ZFR,PAXX,KPNA1,POLE,QARS,MRPL27,SMPD4,YY1,ECPAS,MRPL3 |
| 2.282e-04 | -8.39 | GO_DNA_DEPENDENT_ATPASE_ACTIVITY | MSigDB lists | GO_DNA_DEPENDENT_ATPASE_ACTIVITY | 76 | 24 | 17377 | 2626 |
RECQL,RFC3,CHTF18,HELB,CHD1L,DHX9,SMARCA4,TOP2B,BLM,RFC2,CHD1,RAD54B,XRCC5,RAD51C,RAD18,CHD3,XRCC2,XRCC3,RUVBL2,RBBP4,TOP1MT,GTF2H2,RAD51D,POLQ |
| 2.282e-04 | -8.39 | GO_AUTOPHAGOSOME | MSigDB lists | GO_AUTOPHAGOSOME | 76 | 24 | 17377 | 2626 |
TBC1D12,UBQLN4,ATG9A,RAB7A,PIP4K2C,VTI1A,RAB23,UBQLN2,BECN1,MAP1LC3B,PIP4K2A,SH3GLB1,OPTN,TBC1D17,RALB,RAB24,VMP1,SNAP29,TBC1D14,ORAI1,RPN2,TICAM1,WIPI2,CLN3 |
| 2.282e-04 | -8.39 | KESHELAVA_MULTIPLE_DRUG_RESISTANCE | MSigDB lists | KESHELAVA_MULTIPLE_DRUG_RESISTANCE | 76 | 24 | 17377 | 2626 |
CYTH1,GUK1,TSPAN31,UFC1,MAN1B1,KCTD17,C1orf35,GGA2,STYXL1,BCAP31,MYO1F,LRRC14,C22orf46,CDKN2C,DST,GSTK1,MED8,TMED10,ODF2,SIL1,TAF12,MARCH2,PDLIM5,NXT2 |
| 2.282e-04 | -8.39 | YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_12 | MSigDB lists | YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_12 | 76 | 24 | 17377 | 2626 |
NTPCR,NSDHL,CIRBP,ENSA,EMP3,ARPC1A,MAGED2,CYHR1,GSTK1,GNA12,DECR1,NAP1L1,PDCD6,RBMX,QARS,ERGIC3,EXOC4,IARS2,AHCY,GNAI2,CLN6,CHPT1,HIGD2A,FDFT1 |
| 2.282e-04 | -8.39 | GO_DNA_GEOMETRIC_CHANGE | MSigDB lists | GO_DNA_GEOMETRIC_CHANGE | 76 | 24 | 17377 | 2626 |
GINS1,RECQL,RBX1,HELB,CHD1L,DHX9,TOP2B,BLM,MCM2,CHD1,GINS4,RAD54B,XRCC5,RPS27A,CHD3,MCM5,RAD23B,XPA,HMGB2,RUVBL2,GTF2H2,PURA,POT1,DDB1 |
| 2.284e-04 | -8.38 | PID_AURORA_B_PATHWAY | MSigDB lists | PID_AURORA_B_PATHWAY | 38 | 15 | 17377 | 2626 |
SEPT1,RHOA,BIRC5,TACC1,NSUN2,CUL3,CDCA8,KIF23,RACGAP1,KIF2C,AURKB,SMC2,STMN1,NCAPG,SMC4 |
| 2.286e-04 | -8.38 | FOXI2 (forkhead box I2) | protein interactions | 399823 | 51 | 19 | 17029 | 2761 |
TIMM8B,RECQL,MECP2,BTAF1,NSDHL,UBE4A,IKBIP,XPO7,DDX39A,SYMPK,MYEF2,NUP205,PA2G4,CMSS1,IARS,NUP107,SMPD4,USP11,EEF1D |
| 2.286e-04 | -8.38 | NACA (nascent polypeptide associated complex subunit alpha) | protein interactions | 4666 | 51 | 19 | 17029 | 2761 |
EWSR1,CUL3,BRCA1,MCM2,ISG15,FADD,SUB1,MDM2,HUWE1,ZHX1,UCHL5,H2AFX,BTF3L4,TXLNA,DDX5,TARDBP,BTF3,ATF2,DCTN1 |
| 2.286e-04 | -8.38 | SLAIN2 (SLAIN motif family member 2) | protein interactions | 57606 | 51 | 19 | 17029 | 2761 |
YTHDC1,CYLD,FOCAD,FOPNL,POC1A,CDT1,BRCA1,FXR1,APP,PCM1,MZT2A,GRK2,PRDX5,SMURF1,CARMIL1,TACC3,SRSF10,SRPK2,DCTN1 |
| 2.286e-04 | -8.38 | EPB41L5 (erythrocyte membrane protein band 4.1 like 5) | protein interactions | 57669 | 51 | 19 | 17029 | 2761 |
GPBP1L1,CXXC1,DCAF8,TWNK,SUZ12,UHRF1BP1,PARK7,PIP4K2A,APP,MASTL,NAP1L1,SMAD2,FNTA,BRD2,CWC27,RNF135,ARRB2,DCAF5,SSRP1 |
| 2.286e-04 | -8.38 | MEX3C (mex-3 RNA binding family member C) | protein interactions | 51320 | 51 | 19 | 17029 | 2761 |
DDX58,USP7,PRKDC,HNRNPUL2,ZNF574,ILF3,BMS1,SAFB2,TRIM28,PIP4K2A,EIF3A,CNOT3,LRPPRC,ATXN2L,AP2B1,GLE1,YWHAH,PABPC1,ZC3HAV1 |
| 2.286e-04 | -8.38 | RAB14 (RAB14, member RAS oncogene family) | protein interactions | 51552 | 51 | 19 | 17029 | 2761 |
UNK,ILF3,GBA,LAMTOR3,HNRNPF,TGOLN2,DUSP22,RUFY1,SDHA,APP,RAB2B,OPTN,RPA1,RPA2,CDC42,ATP6V1C1,ATF2,IFI16,TACC3 |
| 2.291e-04 | -8.38 | SCHLOSSER_MYC_TARGETS_AND_SERUM_RESPONSE_UP | MSigDB lists | SCHLOSSER_MYC_TARGETS_AND_SERUM_RESPONSE_UP | 46 | 17 | 17377 | 2626 |
SRP72,NOP2,SNRPB,AMD1,ILF3,UCK2,TMED3,VDAC1,ODC1,TWISTNB,CCDC86,ATP2A2,GEMIN4,PTDSS1,DDB1,SSSCA1,USP13 |
| 2.291e-04 | -8.38 | HEDENFALK_BREAST_CANCER_HEREDITARY_VS_SPORADIC | MSigDB lists | HEDENFALK_BREAST_CANCER_HEREDITARY_VS_SPORADIC | 46 | 17 | 17377 | 2626 |
ST13,FOXM1,CDC123,FAM136A,SLC35B1,CBX3,C1GALT1,VEZF1,PCNA,ITGB8,MTMR4,RAB4A,YBX1,TP53BP2,TOB1,PFKP,GPX4 |
| 2.291e-04 | -8.38 | CHIBA_RESPONSE_TO_TSA | MSigDB lists | CHIBA_RESPONSE_TO_TSA | 46 | 17 | 17377 | 2626 |
ZBED3,RHOA,RRM2,PRPF3,DNAJB1,PRKRA,CDK11A,PRDX1,RHOB,OPTN,SRXN1,HADHB,STAT1,CLU,H3F3A,LYPLA2,NIPSNAP1 |
| 2.292e-04 | -8.38 | GO_NEGATIVE_REGULATION_OF_PHOSPHORYLATION | MSigDB lists | GO_NEGATIVE_REGULATION_OF_PHOSPHORYLATION | 406 | 88 | 17377 | 2626 |
ZBED3,FGFR1OP,ASH1L,TSC2,NF1,FOXM1,DYNLL1,PPP1R15B,FAM129A,SIRT2,CCNB1,LYN,DUSP22,PARK7,PRNP,CALM2,CDKN2C,PIN1,SOCS6,CDKN1B,TARDBP,GPD1L,CTDSP2,STRAP,ANKLE2,SNX25,PPIF,BAK1,PLK1,NCK1,PBK,CUL3,GMFB,EZR,LRP5,DNAJA1,PRPSAP1,SOCS7,PPP2CA,HHEX,DNAJC10,PPP2R5A,STK38,CORO1C,GADD45B,OGT,SOCS4,DVL1,PPP5C,PARD3,PDCD4,HSPH1,GMFG,CIB1,AKT1S1,RGS2,PSEN1,TFAP4,PTPN2,RB1,PTEN,FBXO7,H2AFY,PIK3IP1,MVP,STAT3,SOCS5,TGFB1,PDPK1,TNFAIP3,ZMYND11,PRKDC,PRKAR1B,GBA,MEN1,LEMD2,SH3BP5,MBIP,PRDX3,GPS2,DUSP3,CSK,NUP62,NR2F2,IGBP1,UBE2C,HIPK3,CDKN2A |
| 2.295e-04 | -8.38 | GO_CORE_PROMOTER_BINDING | MSigDB lists | GO_CORE_PROMOTER_BINDING | 147 | 39 | 17377 | 2626 |
H2AFZ,SUZ12,SMARCA4,THRAP3,FOXO3,PARK7,CREM,RB1,NRF1,RRN3,MTA1,ZNF335,H2AFY,CCAR1,SP3,KLF10,BAZ2A,PSPC1,E2F3,WBP2,ELK1,SOX4,KDM3A,UBTF,RBMX,SAFB,STAT6,ARNTL,NFIL3,STAT1,NLRC5,E2F1,RUVBL2,RBPJ,SMAD1,H3F3A,E2F2,HDAC2,IFI16 |
| 2.297e-04 | -8.38 | GSE17721_CTRL_VS_PAM3CSK4_1H_BMDC_UP | MSigDB lists | GSE17721_CTRL_VS_PAM3CSK4_1H_BMDC_UP | 177 | 45 | 17377 | 2626 |
UNK,GOLPH3L,CASP6,PHF23,GADD45G,MRPS26,ASAH1,SIKE1,COMMD5,C19orf48,SSR1,C14orf119,RAP1A,SMC3,NUS1,PPP1R8,DUT,PARL,CORO1A,MRPL48,TOP1MT,PHKG2,TMBIM1,RNF5,LYPLA2,ADCY7,GINS1,BAK1,EIF3L,BAZ2A,IDH3A,ZNF574,FRAT2,MTX1,RPS9,KPNA1,FNTA,JAK1,MFAP1,PPM1G,ACLY,QRSL1,ACAT1,ZFP90,PDXK |
| 2.297e-04 | -8.38 | GSE46606_UNSTIM_VS_CD40L_IL2_IL5_DAY1_STIMULATED_BCELL_DN | MSigDB lists | GSE46606_UNSTIM_VS_CD40L_IL2_IL5_DAY1_STIMULATED_BCELL_DN | 177 | 45 | 17377 | 2626 |
PKP4,DDX47,TP53RK,MCM10,KLHL21,NDUFAF2,WDYHV1,UCK2,HDDC2,MAD2L2,SNRNP25,EIF2S2,AHCTF1,MED8,CD3EAP,TIMM23,ADCY9,BUD31,ATP6V0A2,PRADC1,MSH6,MED22,SNX25,TACC1,CDC123,HNRNPF,LDHA,MFNG,RRM2,TBRG4,PSMG1,RABIF,CDC6,UTP3,ESYT1,LSG1,USP36,PSMC4,ITPRIPL1,PALB2,SETD3,WDR4,NAA20,BYSL,GEMIN7 |
| 2.298e-04 | -8.38 | C5AR2 (complement component 5a receptor 2) | protein interactions | 27202 | 59 | 21 | 17029 | 2761 |
SLC12A7,TELO2,GOLPH3L,C1orf112,BTAF1,TMEM97,AGPAT1,LRRC8A,MCL1,GSTCD,SLC12A9,GUF1,PDXDC1,TUBGCP2,GLMP,ASPHD2,PTPN2,NUS1,ATP13A3,XRCC3,NR2F2 |
| 2.298e-04 | -8.38 | haematopoietic_and_lymphoid_tissue-lymph_node-lymphoid_neoplasm-Hodgkin_lymphoma | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-lymph_node-lymphoid_neoplasm-Hodgkin_lymphoma | 20 | 10 | 17385 | 2587 |
SEC31A,PCM1,CYLD,NRAS,TNFAIP3,PTEN,SF3B1,ETV6,KRAS,HRAS |
| 2.303e-04 | -8.38 | GO_REGULATION_OF_TRANSCRIPTION_FROM_RNA_POLYMERASE_II_PROMOTER | MSigDB lists | GO_REGULATION_OF_TRANSCRIPTION_FROM_RNA_POLYMERASE_II_PROMOTER | 1715 | 310 | 17377 | 2626 |
ZNF496,TXN,H2AFZ,MAX,TSC22D3,HEXB,XIAP,CCNL2,UBE2I,PARK7,USF1,FNIP2,CRY2,ECD,SMARCE1,DNMT1,SENP1,PLK3,AATF,KLF10,GABPA,AKT2,EHMT1,DDX20,AURKB,CBFB,ARF4,ZMYM3,BRMS1,HHEX,SMAD2,BRD2,RPS27A,AXIN1,RPS14,OGT,RNASEL,TFDP2,SMAD1,HDAC2,DDX58,HSPH1,EZH1,ZNF518A,PSEN1,CDC73,JMY,LMNA,TFAP4,KLF16,HDAC7,MEGF8,PHF14,ETV3,FOXK1,ZMYND11,MTA2,MYBL2,ARID1A,ADRB2,CBFA2T2,ELK1,KDM3A,ETS2,SETD3,RBMX,PPP3R1,CEBPG,PIAS2,YY1,RNF14,CDKN2A,EGLN1,ZNF296,DNMT3A,TRERF1,SUZ12,RPS6KA1,RAF1,MAGED1,WDTC1,TCF19,RCOR3,APP,SP100,GMEB1,LPIN2,MAVS,RBM15,ATF2,RPRD1B,CDK12,CGGBP1,SAP30,BRD4,ERF,EID1,DRAP1,CUL3,WBP2,HTATIP2,ELP4,MEF2D,TRIM28,DDX17,TAF2,CHCHD3,VEZF1,HIPK2,SAFB,STAT1,ATF6,BEND3,LRP8,POU3F2,NCOR2,MECP2,TCF3,TRAK1,ABHD14B,WDR5,ETS1,FOXO3,HMG20A,MAD2L2,GTF2F1,WWP2,CCNK,SUV39H2,CREB1,ZNF710,CITED2,NCOA2,MED22,PPP3CA,KAT2A,RFXANK,KLF6,FADD,GPS2,ZHX1,TFDP1,PITX1,HMGB2,DDX5,BRWD3,IGBP1,USF2,CD81,PURA,FAM83G,CCNC,ZBED3,ZNF76,AGRN,UBN1,TAF6L,SIRT2,MAPK14,CREM,TET3,GLIS2,JAZF1,ZNF639,PIK3R2,ETV6,NOC2L,TCEA1,MYBL1,ARID4A,RYBP,PLK1,SP3,DEAF1,RBX1,NCK1,VHL,ZBED5,EZR,LRP5,EAF2,BRCA1,SOX4,PAF1,BRWD1,CHD3,ZNF367,E2F4,ZNF268,BEND6,PSMC1,ZNF564,UBE2D3,PPP1R12A,NACA,MED13L,CHCHD2,CTCF,MEF2A,CDK13,THRAP3,PPP3CB,RLF,ASXL2,CRLF3,SUB1,RB1,NFATC3,MLX,MED10,MED8,SSBP3,MBD2,ZNF746,BUD31,CTR9,TIMELESS,YBX1,MAML1,ZNF189,CREG1,CIC,ERLIN1,LDB1,RTF1,EIF2A,NFATC2IP,IRF5,ZNF174,CAND1,RXRB,PSMC4,NFIL3,NLRC5,ZFP90,RUVBL2,TOB1,N4BP2L2,SMARCD1,MBD1,TCF12,ASH1L,FOXM1,PLAGL2,SMARCA4,IRF3,DUSP22,CHD1,MXD1,SAP130,HNRNPA2B1,NRF1,MDM2,PIN1,TARDBP,STRAP,ZNF770,MOSPD1,RLIM,BTG2,PCGF6,GLO1,NFATC2,MBD3,RBL1,SCAP,STAT6,MAFK,ARNTL,DNAJC17,NCOA1,AKNA,SMURF1,SMAD4,CBX4,BCL2L12,SLC30A9,CTDP1,EYA1,ARID5A,KLF13,HMGN3,PAWR,MXD4,IRF4,BRD7,ARHGEF2,H2AFY,STAT3,TGFB1,RPRD1A,DCAF6,HMGN5,PRKDC,ZNF202,ZMYM5,RCOR1,MEN1,MAPK3,TFEB,ATAD2,TWSG1,TFE3,E2F1,PKD2,RBPJ,NR2F2,ZMIZ1,HRAS,IFI16 |
| 2.305e-04 | -8.38 | endometrioid_adenocarcinoma | COSMIC cancer mutations | endometrioid_adenocarcinoma | 8 | 6 | 17385 | 2587 |
GNAS,KRAS,STK11,NRAS,PTEN,HRAS |
| 2.305e-04 | -8.38 | myxoma | COSMIC cancer mutations | myxoma | 8 | 6 | 17385 | 2587 |
GNAS,KRAS,FUS,EWSR1,NRAS,HRAS |
| 2.305e-04 | -8.38 | insular_carcinoma | COSMIC cancer mutations | insular_carcinoma | 8 | 6 | 17385 | 2587 |
KRAS,NRAS,TFG,CCDC6,HRAS,PTPN11 |
| 2.305e-04 | -8.38 | thyroid-carcinoma-insular_carcinoma | COSMIC cancer mutations | thyroid-carcinoma-insular_carcinoma | 8 | 6 | 17385 | 2587 |
KRAS,NRAS,TFG,CCDC6,HRAS,PTPN11 |
| 2.305e-04 | -8.38 | vipoma | COSMIC cancer mutations | vipoma | 8 | 6 | 17385 | 2587 |
GNAS,KRAS,MEN1,PTEN,VHL,SMAD4 |
| 2.310e-04 | -8.37 | ISY1 (ISY1 splicing factor homolog) | protein interactions | 57461 | 55 | 20 | 17029 | 2761 |
WSB2,CDC40,XAB2,SUZ12,PPIE,CRNKL1,DHX8,KRAS,UBE2I,SF3A2,PSMA6,BUD31,YJU2,AQR,SNRPG,ZNF830,NKAPD1,LUC7L2,CDC5L,PRPF19 |
| 2.310e-04 | -8.37 | UBXN6 (UBX domain protein 6) | protein interactions | 80700 | 55 | 20 | 17029 | 2761 |
COPA,SEPT9,PRKDC,FLOT1,MCL1,MCFD2,CCT8,APP,NPLOC4,DST,DERL1,UBXN2A,PSMD2,ZC3H7B,NSFL1C,VCPIP1,RUVBL2,LMAN1,SMURF1,FAF1 |
| 2.310e-04 | -8.37 | MRPL45 (mitochondrial ribosomal protein L45) | protein interactions | 84311 | 55 | 20 | 17029 | 2761 |
MRPL9,MRPL42,MRPL39,MRPL12,RPL6,ILF3,CUL3,MRPL19,RCC1L,SDHB,MRPL50,NDUFV1,HNRNPR,KBTBD7,GPI,MRPL11,SNRNP70,MRPL13,ZC3H3,MRPL32 |
| 2.310e-04 | -8.37 | SORD (sorbitol dehydrogenase) | protein interactions | 6652 | 55 | 20 | 17029 | 2761 |
BCCIP,GCLM,LDHA,MYH9,RANGAP1,NIT2,ANLN,DDX39A,RAD23A,FLAD1,C12orf10,CAT,PFDN4,AKR1B1,GPI,TCEA1,PIEZO1,METTL26,TALDO1,LDHB |
| 2.312e-04 | -8.37 | GSE37301_HEMATOPOIETIC_STEM_CELL_VS_LYMPHOID_PRIMED_MPP_UP | MSigDB lists | GSE37301_HEMATOPOIETIC_STEM_CELL_VS_LYMPHOID_PRIMED_MPP_UP | 172 | 44 | 17377 | 2626 |
SNX27,CORO7,DNAJC5,DAP,MRI1,HNRNPUL2,TATDN3,SDC2,RRM1,KIF23,SLC12A9,FBXO3,GOLM1,ADD3,MBD2,PHF14,HADHB,UPRT,NDUFS8,CDC25B,RBM15,ELOVL5,GCC2,PPP3CA,ILF3,RRM2,DIDO1,WBP1,FANCE,TRIM28,RPSA,RHEB,RPL32,TTLL4,CHD3,STAT6,ATF6,SAMD8,FAM126A,CABIN1,PSAP,RUFY3,TOB1,S100PBP |
| 2.318e-04 | -8.37 | REACTOME_CLEAVAGE_OF_GROWING_TRANSCRIPT_IN_THE_TERMINATION_REGION_ | MSigDB lists | REACTOME_CLEAVAGE_OF_GROWING_TRANSCRIPT_IN_THE_TERMINATION_REGION_ | 42 | 16 | 17377 | 2626 |
SRSF11,CDC40,ZNF473,SNRPB,SRSF6,SRSF4,RBM8A,RNPS1,SLBP,SNRPG,SRSF3,SRSF5,SNRPD3,SRSF1,PAPOLA,CSTF1 |
| 2.318e-04 | -8.37 | GRADE_METASTASIS_DN | MSigDB lists | GRADE_METASTASIS_DN | 42 | 16 | 17377 | 2626 |
PPIB,POLR2I,H2AFZ,PSMA6,PSMD8,DYNLL1,TCF3,CDCA3,OLA1,PMF1,TFG,PDCD11,AP2S1,OAZ1,NRBP1,PSMC4 |
| 2.318e-04 | -8.37 | MODY_HIPPOCAMPUS_PRENATAL | MSigDB lists | MODY_HIPPOCAMPUS_PRENATAL | 42 | 16 | 17377 | 2626 |
RPL37,PCNA,EIF2S2,EIF4A3,SRSF6,GADD45G,EFTUD2,RPL8,H2AFX,RPL19,WBP1,RBPJ,BTF3,H2AFV,UBE2C,CCNB2 |
| 2.321e-04 | -8.37 | DNA-directed RNA polymerase II, holoenzyme | cellular component | GO:0016591 | 120 | 33 | 18223 | 2701 |
INTS2,CTDP1,POLR2K,ZNF768,TAF6L,CDC73,GTF2F1,MED8,MED10,INTS7,INTS1,CTR9,INTS12,TAF5L,TCEA1,GTF2H2,RPRD1B,ERCC1,RPRD1A,POLR2I,POLR2L,POLR2G,KAT2A,POLR2D,RTF1,EDF1,POLR2A,PAF1,TAF2,POLR2J,TBPL1,TAF12,TAF6 |
| 2.322e-04 | -8.37 | GSE20484_MCSG_VS_CXCL4_MONOCYTE_DERIVED_MACROPHAGE_UP | MSigDB lists | GSE20484_MCSG_VS_CXCL4_MONOCYTE_DERIVED_MACROPHAGE_UP | 167 | 43 | 17377 | 2626 |
NDUFS1,SCOC,MRPL42,SUCLG1,NDUFAF2,WDR13,MAGED1,SLC2A1,UCK2,LAGE3,DNAJC24,ARFIP2,FOXO3,XPR1,VAV1,APLP2,GART,KLHL5,FJX1,BTF3L4,GEMIN6,SUCLG2,NDUFB9,MRPL21,NDUFA3,IFT46,RPL22L1,RPL29,OAF,MRPL12,TUFM,NDUFB1,CHAF1A,SDHB,ALG3,MRPL2,RPS27A,HIPK2,COX7A2L,COX5A,SIL1,MAPK1,TSTD2 |
| 2.323e-04 | -8.37 | GSE25677_R848_VS_MPL_AND_R848_STIM_BCELL_DN | MSigDB lists | GSE25677_R848_VS_MPL_AND_R848_STIM_BCELL_DN | 157 | 41 | 17377 | 2626 |
IMMT,GOLIM4,FEZ2,GMFG,TSC22D3,SRGN,DBF4,STARD7,DHX9,CRLF3,GLRX3,WWP2,CSDE1,PCNA,EIF4A3,CAPZA1,TRA2B,YBX1,BCAP29,POLR1B,PIK3IP1,NCOA2,MTA2,PPP1R21,CIRBP,WBP1,USP22,ADRB2,CYFIP2,ZFAND5,PICALM,RPS9,EIF3K,WAS,MAPK6,CEP55,ASNA1,SPCS3,MAP3K5,PDCD4,ATMIN |
| 2.332e-04 | -8.36 | RELA (RELA proto-oncogene, NF-kB subunit) | protein interactions | 5970 | 298 | 72 | 17029 | 2761 |
USP7,REPS2,TSC22D3,SUZ12,CSNK2A1,IRF3,SNRPD3,COMMD5,CCNB1,PRKACA,BECN1,MAPK14,COMMD6,COMMD8,MDM2,KDM2A,PIN1,AKAP8,SOCS6,TP53BP2,CNNM3,MTPN,CARM1,PLK1,SP3,BIRC3,AATF,GOPC,RNF25,EHMT1,BRCA1,PPP2CA,BRMS1,WAS,HSPA4,STAT6,MAFK,STAT1,OGT,KPNA2,FUS,PDCD11,SMAD4,ABCA1,HDAC2,COMMD10,UBE2D3,NCOR2,DHX9,NKRF,HERC3,CENPJ,AFF1,STAT3,EEF1D,PHF10,KAT2A,PRKDC,PKM,MEN1,COMMD4,POLR2A,KEAP1,CSNK1G1,MED15,PML,SNRNP70,UBE2C,TAF6,USF2,FAF1,CDKN2A |
| 2.332e-04 | -8.36 | TFAP4 (transcription factor AP-4) | protein interactions | 7023 | 106 | 32 | 17029 | 2761 |
ARID2,CUL1,CTCF,INO80E,TERF2IP,SAP130,PCNA,MBD2,ZNF335,BRD7,SMARCE1,TERF2,SP3,SNRNP200,FOXK1,BTAF1,EHMT1,NFATC2,ARID1A,BRCA1,XRCC5,GOLGA2,UHRF2,CABIN1,HMGB2,RBPJ,NR2F2,PPP6R3,WDR45B,USF2,ARRB2,HDAC2 |
| 2.332e-04 | -8.36 | CEP290 (centrosomal protein 290) | protein interactions | 80184 | 106 | 32 | 17029 | 2761 |
MIF,FGFR1OP,DDX47,MAPRE1,LUZP1,PAWR,HAUS4,BCAP31,CALM2,CEP104,CCP110,KIF14,GPATCH1,ANP32A,TARDBP,AHCY,PTGES3,CHTOP,MTPN,USO1,HMGN1,CCDC138,FOPNL,LDHA,SREK1,ECH1,CAND1,HAUS8,NEK1,PCM1,CCDC14,YWHAH |
| 2.332e-04 | -8.36 | LARP1 (La ribonucleoprotein domain family member 1) | protein interactions | 23367 | 124 | 36 | 17029 | 2761 |
NIFK,IVNS1ABP,SUZ12,GSPT2,CUL1,CSNK2A1,BCL2L1,RTKN,ZBTB21,STRBP,KIF13B,TARDBP,ZC3H3,LUC7L2,NOL12,PPAN,EIF3L,CUL3,RPL6,RPS10,BRCA1,LUC7L,RPS9,EIF3A,GIGYF1,CAND1,EIF3K,CLK3,DGCR8,RPS14,CDCA5,YWHAZ,SNRNP70,HNRNPDL,ZC3HAV1,IFI16 |
| 2.353e-04 | -8.35 | MAGED1 (MAGE family member D1) | protein interactions | 9500 | 115 | 34 | 17029 | 2761 |
MAGED1,UBXN1,XIAP,DNAAF5,DAZAP2,COPG2,NUP205,FANCI,ANKRD28,RBM23,PCNA,SMC3,IARS,FBXO7,NOC2L,TFG,SLC25A1,TIMM50,PLK1,TELO2,AATF,CUL3,TOLLIP,TRIM28,MPC1,SMAP2,MAPK3,MAGED2,PCM1,CCDC14,PITX1,LRPPRC,KPNA2,CCDC59 |
| 2.353e-04 | -8.35 | TXLNA (taxilin alpha) | protein interactions | 200081 | 115 | 34 | 17029 | 2761 |
KARS,FGFR1OP,NACA,RCOR3,IARS,TXLNA,BTF3L4,CEP63,TP53BP2,RNF135,SMARCE1,PPP1R21,CUL3,GORASP2,BRCA1,AZI2,DHX15,RXRB,DDX17,C1orf122,SDHB,EPRS,MBIP,EIF4ENIF1,PCM1,GOLGA2,NSMCE2,QARS,NUP62,WIPI2,RUVBL2,BTF3,FUS,PFKP |
| 2.381e-04 | -8.34 | germ_cell_tumour | COSMIC cancer mutations | germ_cell_tumour | 877 | 168 | 17385 | 2587 |
NF1,TMEM41B,ABCC10,CSNK2A1,MAPK14,EEF2K,CDK5,ABL2,NEK6,ATG3,PIK3R2,XRCC2,HADHB,NUP153,SRPK2,USP34,PLK1,PLK3,NRAS,AKT2,VHL,PBK,NOL8,LRBA,TLK1,AURKB,BRCA1,STK17B,CHAF1A,MAP3K4,EIF4ENIF1,AXIN1,LIMK1,SOCS4,STK11,RNASEL,CHEK2,PTOV1,LIME1,EWSR1,MUT,DHPS,PRKAA1,TRIO,DHX9,CDK13,ADCK5,EIF2AK4,PDXDC1,SRRT,JMY,MED10,INTS7,KIF13B,MSH2,DAPK1,ATP6V0A2,PHKG2,PABPC1,CSNK1G3,ABCC1,CIC,UHRF1BP1,MAP4K3,EIF2AK1,KRAS,PTTG1IP,MAP2K2,MTR,ZDHHC3,SLTM,DAPK3,PHF6,MASTL,GNAS,DERL1,MBIP,RBM25,CDC27,SNAP23,CABIN1,TCOF1,YY1,MYO9A,MAP3K5,CDK2,UNC13C,NRBP1,CDKN2A,CHMP2A,DNMT3A,TP53RK,TRIP10,CHERP,RAF1,RPS6KA1,SF3B1,URB2,EIF3D,SMARCA4,ATP6V1B2,PRKACA,LYN,TWF2,APP,CHD1,COMMD8,FLAD1,HNRNPA2B1,ANKLE1,PRKD3,PDK2,ATP2A2,KDM2A,SP100,CCDC50,CDK12,SCYL3,ADCY7,CCT2,BRD4,PSMA8,MAP4K4,PKMYT1,BUD13,TRIM28,RHBDF2,JAK1,CLK3,FASTK,HIPK2,STK38,PDCD11,MAPK1,SMAD4,ADAM23,PRPF4B,R3HCC1L,SCYL1,ATG2B,CSNK1A1,SCYL2,FOXO3,FGFR3,PTEN,PTPN11,H2AFY,CAMK2G,MYO5A,SPTAN1,GINS1,RPAP3,PDPK1,CSNK1G2,NEK7,ASPM,TOP3A,HAGH,MACF1,MARK2,BSDC1,MAPK3,NEIL3,MAPK6,WDR91,RPS6KC1,HRAS,HIPK3 |
| 2.397e-04 | -8.34 | ZHONG_RESPONSE_TO_AZACITIDINE_AND_TSA_DN | MSigDB lists | ZHONG_RESPONSE_TO_AZACITIDINE_AND_TSA_DN | 63 | 21 | 17377 | 2626 |
LYRM4,GOLPH3L,MECP2,PPIE,RBM8A,CIRBP,KIF15,PMF1,GOSR1,HSPBP1,CCNA2,RBMX,EIF2D,CTBS,SUCLG2,PDCD2,HMGB2,APOOL,MOB1A,NGLY1,LRP8 |
| 2.406e-04 | -8.33 | regulation of gene silencing by miRNA | biological process | GO:0060964 | 108 | 31 | 17256 | 2622 |
TGFB1,NCOR2,PPP3CA,NDC1,POLR2I,NUP188,POLR2G,POLR2L,POLR2K,RAE1,AGO2,DHX9,NUP54,POLR2D,NUP155,FXR1,MAP2K2,NUP205,POLR2A,NUP210,POLR2J,NUP107,NUP62,NUP153,DDX5,H3F3A,STAT3,NUP85,NUP58,AAAS,SEH1L |
| 2.410e-04 | -8.33 | nuclear transcriptional repressor complex | cellular component | GO:0090568 | 31 | 13 | 18223 | 2701 |
ETV3,BAZ2A,CHD3,MTA2,APPL2,CSNK2A1,DDX20,SIRT2,RBBP4,MBD3,TNRC18,APPL1,HDAC2 |
| 2.414e-04 | -8.33 | AXIN1 (axin 1) | protein interactions | 8312 | 80 | 26 | 17029 | 2761 |
USP7,MAPRE1,TNFAIP3,TSC2,FOXM1,WDYHV1,LRP5,CSNK1A1,MAP3K4,GNAS,PPP2CA,TSC1,SMAD2,PPP2R5A,AXIN1,HIPK2,PIN1,PML,AXIN2,ANP32A,DVL1,SMURF1,STRAP,DVL2,CARM1,CSNK1D |
| 2.414e-04 | -8.33 | PFKP (phosphofructokinase, platelet) | protein interactions | 5214 | 80 | 26 | 17029 | 2761 |
PPIB,EID1,DYNLL1,AGO2,CUL3,PSMG1,DNAJC9,BRCA1,PKM,MCFD2,MCM2,PCBP1,COMMD4,EPRS,TXLNA,FUS,WIPI2,DMWD,MCMBP,NIPSNAP2,CD81,NMD3,POT1,TERF1,PARD3,CDC5L |
| 2.415e-04 | -8.33 | CEP135 (centrosomal protein 135) | protein interactions | 9662 | 166 | 45 | 17029 | 2761 |
FGFR1OP,MAPRE1,CYLD,LUZP1,MAGED1,PROSER3,HAUS4,CSNK1A1,MCTS1,DLG5,RAB8A,CCP110,SYNM,KIF14,TXLNA,GPATCH1,TP53BP2,MTPN,DVL2,TMEM160,SRP72,PLK1,CCDC138,FOPNL,CAMSAP1,SREK1,ADSL,RCOR1,NUP155,ERC1,ECH1,HAUS8,KEAP1,COMMD3-BMI1,PCM1,SEC23IP,SPATA2,CCDC14,ODF2,CEP55,KIAA1328,DVL1,NDE1,GEN1,YWHAH |
| 2.416e-04 | -8.33 | protein localization to membrane | biological process | GO:0072657 | 421 | 91 | 17256 | 2622 |
SYS1,AGRN,RPLP2,RAB11B,ANK3,SSR1,RPL23A,RPL11,MOAP1,CDK5,RAB8A,ATG3,ZFYVE27,ARL5A,SRP72,RPL29,SEC61B,RPL35,AKT2,RPL38,EZR,NUP155,ICMT,ARL5B,RPS9,RPSA,OPTN,RPL37,TRAM2,PEX5,CHMP4A,TIMM13,HSPA4,SEC61A1,RPS27A,GRIPAP1,TIMM29,RPS14,TULP3,RPLP1,CHMP4B,DVL1,ROCK1,SMURF1,RPS26,TSPAN5,C2CD5,PARD3,RPS15,RPS2,GOLPH3L,NKD2,FLOT1,NUP54,RPL15,RAB11A,WRB,RAPGEF6,ATG4A,RPL17,PPIL2,ARL6IP1,RPL19,MYO5A,TMED2,PACS2,ZDHHC18,GCC2,DENND4C,RPL6,RPL8,RPS10,RPS24,SSR2,PACS1,RAB3IP,RPL27A,MACF1,ZDHHC3,SH3GLB1,RPL36,FNTA,HGS,GOLGA4,RPL32,GOLGA7,NSF,EXOC4,ZDHHC7,FAM126A,SSNA1 |
| 2.439e-04 | -8.32 | DNMT1 (DNA methyltransferase 1) | protein interactions | 1786 | 93 | 29 | 17029 | 2761 |
SP3,USP7,DNAJC2,DNMT3A,BAZ2A,CXXC1,MTA2,SUZ12,DYNLL1,MECP2,BRAP,BRCA1,CCNB1,MBD3,TRIM28,ZFR,RB1,PCNA,HSPA4,MTA1,MBD2,E2F1,UHRF2,SNRPG,RBBP4,CDK2,STAT3,DNMT1,HDAC2 |
| 2.443e-04 | -8.32 | G0 and Early G1 | REACTOME pathways | R-HSA-1538133 | 25 | 12 | 10287 | 1696 |
LIN9,PCNA,CCNA2,RBL1,E2F4,TFDP1,E2F1,MYBL2,CDC6,TFDP2,RBBP4,CDK2 |
| 2.448e-04 | -8.32 | EGF/EGFR Signaling Pathway | WikiPathways | WP437 | 162 | 43 | 5312 | 837 |
REPS2,RAF1,RPS6KA1,RAC1,VAV2,EPN1,MEF2A,STMN1,MAPK14,STAM,CRKL,VAV1,RAP1A,PCNA,SHC1,CDC42,PTEN,RALB,ARHGEF1,PIK3R2,PTPN11,AP2B1,CREB1,STAT3,ABI1,CFL1,PDPK1,NCK1,MYBL2,KRAS,MEF2D,ELK1,MAP2K2,MAP3K4,HGS,JAK1,CSK,E2F1,STAT1,ROCK1,MAPK1,HRAS,AP2S1 |
| 2.450e-04 | -8.31 | FBXO3 (F-box protein 3) | protein interactions | 26273 | 22 | 11 | 17029 | 2761 |
FBXO3,TNFAIP3,RBX1,HIPK2,PML,CUL3,CUL1,PTPDC1,MCM2,SMURF1,CDC73 |
| 2.450e-04 | -8.31 | NGDN (neuroguidin) | protein interactions | 25983 | 22 | 11 | 17029 | 2761 |
RPS2,AATF,ZNF512,RPS14,SUZ12,UTP3,BORA,BECN1,GPATCH4,IFI16,SRPK2 |
| 2.451e-04 | -8.31 | MBD | smart domains | SM00391 | 11 | 7 | 9493 | 1367 |
MBD1,MBD6,MBD3,BAZ2A,MECP2,MBD2,MBD4 |
| 2.451e-04 | -8.31 | BAH | smart domains | SM00439 | 11 | 7 | 9493 | 1367 |
ORC1,ASH1L,PBRM1,TNRC18,DNMT1,MTA1,MTA2 |
| 2.462e-04 | -8.31 | carbohydrate derivative binding | molecular function | GO:0097367 | 2160 | 388 | 17224 | 2647 |
RAB14,ABCC10,TAP1,DHX8,GLUD1,UBE2I,EEF2K,KIFC1,CDK5,NEK6,RAB4A,ATP13A3,PDS5B,DNM2,UPRT,SUCLG2,MAST2,PLK3,RHOBTB3,NRAS,AKT2,PBK,KIF15,MKI67,DDX20,SMC2,AURKB,MCM2,RFC2,RAB22A,RAB2B,ARF4,MAP3K4,MKNK1,KIF18B,LIMK1,MYO18A,RNASEL,LONP2,PFKP,DDX42,DDX58,HSPH1,RECQL,CHTF18,RHOC,TRIO,GSPT2,PRKAA1,DHX9,RRM1,RAB23,CERK,KIF23,TOP2B,EIF2AK4,RTKN,DDX56,SMC3,MCM5,EFTUD2,CTPS1,MSH2,DAPK1,RTCB,PIKFYVE,GNAI2,PHKG2,UBE2QL1,CARS2,DDX28,COQ8A,MAPKAPK3,DHX29,NOA1,PGS1,TYW1,GTPBP4,PIP4K2C,SEPT8,RIT1,PKM,ABCF1,MAP2K2,CCT8,RHOB,PI4K2A,XRCC5,ADSS,PTPRF,EPRS,NSF,CSK,CSNK1G1,DCK,QARS,ACLY,MAP3K5,CDK2,NRBP1,ACSF2,ZNF207,RHOG,KARS,ABCA3,TP53RK,RAB11B,RPS6KA1,RAF1,CHD1L,KIAA0232,ACTR3,RAC1,OLA1,TPX2,MYH9,EFL1,PRKACA,CBWD5,APP,FLAD1,RAB21,PRKD3,APLP2,ATP2A2,RALB,UBA5,ADCY9,CLCN6,SEPT11,TAP2,AQR,ARL5A,CDK12,ADCY7,CCT2,ULK3,ATP13A1,MAP4K4,TAOK1,PFKFB3,GALK2,PKMYT1,DNAJA1,RAB1A,MAT2A,DHX57,DDX17,KIF2A,RAD51C,HSPA4,JAK1,RAB24,GUCY1B1,HIPK2,CBWD1,PDXK,PPP5C,CSNK1D,TUBB,DYNC1LI2,RHEBL1,PRPF4B,POLQ,GALK1,ANXA6,TWNK,IP6K2,ATP5F1B,BLM,IFT27,PMVK,RAB11A,PIP5K1C,SRXN1,GATC,CBWD2,ARF5,TTLL12,ST8SIA2,MAP3K14,UBE2M,MSH6,SMC4,PDPK1,TK1,DDX24,GUK1,NEK7,BMS1,RHOT1,DDX39A,GUF1,KIF11,MARK2,MYO1F,GNA12,KIF18A,LTBP4,TTLL4,MAPK6,ASNA1,DDX5,PSAP,DDX52,ADA2,DDX47,UBE2E2,ST13,AGRN,YTHDC2,MCCC1,CSNK2A1,UBE2Q1,UBE2Z,ABCB10,KIF2C,MAPK14,PAPOLA,PRNP,ABL2,RAB8A,RAP1A,CDC42,EIF4A3,RAB35,TRMU,XRCC2,KIF22,RP2,EIF5,ABCC5,SRPK2,PLK1,LARS,SNRNP200,SEPT9,HARS,TLK1,CDC6,RAB5B,LSG1,STK17B,DHX15,RHEB,DPYSL3,SEPT1,CHD3,IARS2,BAZ1B,QRSL1,ACTB,STK11,CHEK2,VPS4A,ROCK1,PSMC1,SEPHS2,UBE2D3,CDK13,THRAP3,RAB6A,CHKA,UBE2Q2,KIF13B,GLTP,ALDH18A1,N4BP2,CSNK1G3,ABCC1,NTPCR,AACS,ACSL3,KRAS,MAP4K3,EIF2AK1,UBE4B,SEPT7,DAPK3,BBS12,MASTL,PSMC4,GNAS,PRPS2,NLRC5,RUVBL2,ATP5F1A,MYO9A,EHD4,UGP2,UCK2,PMS2,SMARCA4,RRAGC,UCK1,CHKB,ORC1,ATP6V1B2,LYN,TWF2,CHD1,MIEF1,FARSA,PDK2,IARS,SAR1A,NVL,KIF14,SCYL3,ACSL5,RPL29,CLCN3,CGAS,RAB7A,ARL5B,RAD54B,DAP3,ATP1A1,IDE,DHX16,CLK3,STK38,FASTK,XRCC3,SCARB1,MAPK1,CHID1,ABCA1,ZNF146,RAD51D,KIF3B,NADSYN1,SHPRH,TOR3A,GNE,SCYL1,SMC6,ARFIP2,ARF1,MYO9B,CDK11B,CSNK1A1,SCYL2,PIP4K2A,GFM2,WRNIP1,KIF5B,GTPBP3,STARD9,FGFR3,CTSS,NDUFV1,GART,GRK2,ABCD1,DDX31,POLR1B,CAMK2G,MYO5A,CSNK1G2,RHOA,PRKDC,HELB,BTAF1,ATP2C1,ABCF2,TUFM,PRKAR1B,NADK2,PNPLA8,RHOT2,CDK11A,TARS,MAPK3,DDX23,HSPA1B,MFN2,CTSL,RAB18,NEK1,UPF1,ATAD2,CTBS,UBE2C,RPS6KC1,HRAS,HIPK3,TYW1B |
| 2.487e-04 | -8.30 | SYNE1 (spectrin repeat containing nuclear envelope protein 1) | protein interactions | 23345 | 36 | 15 | 17029 | 2761 |
SH3BP5,CDC42,PPME1,SUZ12,NUP107,NLN,CEP63,MCM2,ECPAS,USP21,CAPN1,IFI16,LMNA,TERF2,CDC5L |
| 2.487e-04 | -8.30 | DCLRE1C (DNA cross-link repair 1C) | protein interactions | 64421 | 36 | 15 | 17029 | 2761 |
ANKRD28,PRKAB1,TRIM26,CDC27,GOLGA2,PRKDC,PRKAA1,PRKAR1B,DDX20,CDKN1B,BRCA1,PPP6R2,PPP6R1,DDB1,XRCC5 |
| 2.487e-04 | -8.30 | NABP2 (nucleic acid binding protein 2) | protein interactions | 79035 | 36 | 15 | 17029 | 2761 |
SUGP1,PPIF,SARNP,NDUFA2,CENPJ,LUC7L3,INTS1,RBMS1,CUL1,SEPT11,BRCA1,NDUFA7,VPS4A,BUD13,EDRF1 |
| 2.487e-04 | -8.30 | WRNIP1 (Werner helicase interacting protein 1) | protein interactions | 56897 | 36 | 15 | 17029 | 2761 |
DDX58,FGFR1OP,PCNA,SMAD2,RAD18,PIN1,SRSF4,NUP107,IRF3,USP11,TOLLIP,TRIM28,ATMIN,CDC5L,WRNIP1 |
| 2.493e-04 | -8.30 | Cysteine and methionine metabolism | KEGG pathways | hsa00270 | 44 | 17 | 7161 | 1149 |
SRM,MAT2B,GCLM,DNMT3A,GOT2,MDH2,AMD1,MRI1,LDHA,AHCY,MDH1,AHCYL1,DNMT1,MTR,MAT2A,BCAT2,LDHB |
| 2.493e-04 | -8.30 | Cysteine and methionine metabolism | KEGG pathways | ko00270 | 44 | 17 | 7161 | 1149 |
SRM,MAT2B,GCLM,DNMT3A,GOT2,MDH2,AMD1,MRI1,LDHA,AHCY,MDH1,AHCYL1,DNMT1,MTR,MAT2A,BCAT2,LDHB |
| 2.493e-04 | -8.30 | regulation of cellular protein metabolic process | biological process | GO:0032268 | 2568 | 450 | 17256 | 2622 |
FGFR1OP,TXN,TSC2,MAP3K7CL,XIAP,YTHDF3,CCNL2,CCNB1,UBE2I,EIF1B,PPP1R16B,RBM4,RIC1,PARK7,FBXO22,EEF2K,CDK5,CALM2,CDKN2C,PA2G4,FIZ1,RAD23B,CRY2,FNIP2,CDC25B,PLCL2,DNMT1,SENP1,MLST8,BAK1,PLK3,AKT2,PBK,MRNIP,TOPORS,DCUN1D5,EIF3A,IWS1,MAP3K4,BRMS1,HHEX,MKNK1,RPS27A,RPS14,LIMK1,AXIN1,PRDX5,OGT,ARRB2,ZNF598,HDAC2,PDCD4,SVIP,PPIB,HSPH1,CLSPN,GMFG,PHF23,GADD45G,PRKAA1,DHX9,CYCS,EIF2AK4,NOTCH2,PSEN1,METTL3,VPS25,WDR48,CNOT3,CFLAR,DDRGK1,NDUFS4,CD59,TFAP4,FKBP1A,MEX3C,FBXO7,PPP4R1,DAPK1,MYDGF,MVP,GNAI2,PABPC1,PPP6R1,NSUN4,SOCS5,EIF5A,CYFIP1,RB1CC1,MAPKAPK3,ZMYND11,GTPBP4,ADRB2,PTTG1IP,CYFIP2,FXR1,KDM3A,EIF4H,MAP2K2,FAS,XRCC5,DERL1,EPRS,HSPBP1,FNTA,GOLGA2,DUSP3,CSK,QARS,FAM83D,CABIN1,TCOF1,PPP6R3,MAP3K5,RNF14,RNF139,ALS2,CDKN2A,KARS,PPP1R37,SARNP,ATXN3,GGNBP2,RPS6KA1,CAST,RAF1,EIF3D,PTTG1,MAGED1,RAC1,TPX2,MYH9,CREBL2,DAZAP2,PRKACA,ANKIB1,APP,PAIP2,TERF2IP,CRKL,APLP2,SHC1,RALB,MTA1,UCHL5,DDA1,ADCY9,SOCS6,MRPS27,NSFL1C,CDKN1B,RNF19A,MAVS,CLN6,GPD1L,CDK12,PDCL3,ADCY7,ANKLE2,SHOC2,PSRC1,BRD4,CDC123,EID1,KAT7,MAP4K4,TAOK1,WBP2,RPL38,POLR2D,CUL3,CIRBP,ELP4,CDCA2,PKMYT1,DNAJA1,RAB1A,SERP1,SOCS7,PPP2CA,EIF3K,PPP2R5A,CORO1C,HIPK2,RPLP1,TICAM1,TRIM32,PPP5C,LRP8,CSNK1D,USP13,RPS2,MECP2,ZFP91,HABP4,FLOT1,SECISBP2,AKT1S1,BLM,HMG20A,FOXO3,MAD2L2,PPP1R3B,CCNK,PDCD10,PTEN,PPP1R8,PTPN11,AXIN2,LTN1,FEM1B,CNOT6L,MAP3K14,PDPK1,ZFP64,KAT2A,LONRF3,TNFAIP3,JTB,ILF3,MARK2,PICALM,FADD,PRDX1,SH3BP5,GNA12,KEAP1,HGS,GPS2,PRDX3,PARG,LRPPRC,PML,KHSRP,PPP1R11,PSAP,WDR91,CD81,PARP10,IGBP1,CPEB2,PURA,FAF1,ZBED3,CCNC,NF1,KMT2E,PPP1R15B,FAM129A,RBM8A,ENSA,DNAJC24,CSNK2A1,NENF,SIRT2,UBQLN2,S1PR2,MAPK14,BIRC2,FANCI,ZER1,PRNP,RAP1A,EIF4A3,IL6ST,METTL14,PIK3R2,NOC2L,EIF5,MTPN,CDC37,RYBP,PLK1,COPS8,RBX1,NCK1,GMFB,EZR,CDC6,UBE2V1,LRP5,BRCA1,SOX4,PAF1,GEMIN5,EIF4ENIF1,SOCS4,CAB39,ADAM9,STK11,CHEK2,CLU,ROCK1,DVL1,CLN3,PSMC1,PPP1R2,PPP1R12A,GORASP1,PHB2,DNAJB2,UBXN1,NKD2,LAMTOR3,CIB1,TIA1,PM20D2,RGS2,CNOT11,RHBDD1,APOPT1,RB1,ARL6IP1,ZNF335,CTR9,BCL2,MDFIC,RBM3,GLE1,ATP5IF1,OXR1,GBA,KRAS,EIF2AK1,MAP4K3,RTF1,EIF2A,EIF4G2,DAPK3,ISG15,MASTL,PSMC4,TSC1,MBIP,SYNCRIP,NSMF,SIAH2,NUP62,RUVBL2,EHD4,TOB1,RNF114,BCCIP,USP7,ASH1L,TRAF7,IFI27L1,FOXM1,SUMO2,LYN,DUSP22,BCAP31,PAIP1,RPL11,RAD23A,USP5,UBXN2A,MDM2,TNFAIP8,PIN1,PPME1,KIF14,AKAP8,PDCD2,TARDBP,CHTOP,F2R,STRAP,ABI1,CTDSP2,HTRA2,DVL2,CHP1,SNX25,UBQLN4,TIMP2,BIRC3,POLR2G,BTG2,EDEM2,PEF1,TOLLIP,RPS9,EIF3H,DNAJC10,IDE,TAB2,HNRNPR,UBXN2B,STK38,TIMM17A,GADD45B,ARNTL,PLGRKT,SMURF1,MAPK1,SMAD4,PPP2R2D,PARD3,MIF,BCL2L12,UNK,MIF4GD,TRIP12,DAP,AGO2,DCUN1D4,CSNK1A1,FBXO5,PTPN2,FASTKD3,FGFR3,TANK,DUS2,H2AFY,BRD7,ARHGEF2,ATG13,STAT3,TGFB1,SAMD4B,COA3,TELO2,PPP1R9B,ADAM17,RHOA,PRKDC,PRKAR1B,RFFL,MEN1,SYMPK,MAPK3,HSPA1B,CNOT9,LEMD2,NEK1,UPF1,PDCD6,PLAA,BIRC5,TWSG1,OSBPL8,GLG1,KMT2B,PKD2,NR2F2,UBE2C,HRAS,HIPK3,IFI16 |
| 2.507e-04 | -8.29 | ZF_PHD_1 | prosite domains | PS01359 | 78 | 23 | 12060 | 1670 |
PHF20L1,PHF10,ASH1L,KMT2E,SHPRH,ZMYND11,CXXC1,PHRF1,NSD3,DIDO1,KMT2C,TCF19,TRIM28,BRPF3,SP100,KDM2A,CHD3,PHF14,UHRF2,KMT2B,INTS12,BAZ1B,FBXL19 |
| 2.518e-04 | -8.29 | PID_PDGFRB_PATHWAY | MSigDB lists | PID_PDGFRB_PATHWAY | 128 | 35 | 17377 | 2626 |
WASF2,RAF1,RAC1,ACTR3,VAV2,NCKAP1,LYN,PTPN2,RAP1A,SHC1,PTEN,ARPC5,PIN1,PIK3R2,RAB4A,DNM2,PTPN11,STAT3,ABI1,NRAS,RHOA,NCK1,KRAS,ELK1,CYFIP2,MAP2K2,MAPK3,PPP2CA,CSK,ARAP1,STAT1,YWHAZ,YWHAH,MAPK1,HRAS |
| 2.519e-04 | -8.29 | GO_CELLULAR_RESPONSE_TO_PEPTIDE | MSigDB lists | GO_CELLULAR_RESPONSE_TO_PEPTIDE | 266 | 62 | 17377 | 2626 |
MAX,AGTRAP,WDTC1,ATP6V1B2,AP3S1,PRKACA,LYN,GNB2,EEF2K,PTPN2,USF1,PDK2,ATP6V0B,RAB8A,MDM2,CCNA2,SHC1,PIK3R2,ADCY9,AKR1B1,ATP6V0A2,ANXA5,ARHGEF2,CREB1,AHCYL1,STAT3,ATP6V0D1,MYO5A,ADCY7,ATP6V1G1,CDC5L,PDPK1,KLF10,AKT2,PRKDC,DENND4C,GNG7,PRKAR1B,SLC26A6,ATP6V0A1,RANGAP1,CDC6,SRSF5,MEN1,KLF6,PDE3B,APPL1,MAPK3,AKAP1,SOCS7,GNAS,ATP6V1D,IDE,CSK,OGT,ATP6V0C,ATP6V1C1,CDK2,MAPK1,ATP6V0E1,CPEB2,SLC25A33 |
| 2.530e-04 | -8.28 | MODULE_308 | MSigDB lists | MODULE_308 | 72 | 23 | 17377 | 2626 |
PDCD6IP,DEPDC1,FOXM1,POLR2K,TRAK1,UCK2,ALKBH5,MYBL2,TBRG4,ZNF267,CCNB1,TAZ,FBXO5,BIRC5,SH3BP1,INTS7,TBC1D14,SEL1L,E2F1,ATF6,CORO1A,DNMT1,TACC3 |
| 2.530e-04 | -8.28 | YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_7 | MSigDB lists | YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_7 | 72 | 23 | 17377 | 2626 |
WSB2,CCT2,CHERP,PPP1R15B,RAB7A,MRPL43,MRPS26,FAM136A,UBQLN2,BRIX1,NCDN,BCAT2,KIF5B,HNRNPA2B1,ATP1A1,HSPA4,BRD2,DDA1,PPM1G,ZBTB22,CNN2,HRAS,CBX4 |
| 2.533e-04 | -8.28 | GSE43955_TGFB_IL6_VS_TGFB_IL6_IL23_TH17_ACT_CD4_TCELL_60H_UP | MSigDB lists | GSE43955_TGFB_IL6_VS_TGFB_IL6_IL23_TH17_ACT_CD4_TCELL_60H_UP | 193 | 48 | 17377 | 2626 |
RMND5A,SYS1,GMFG,ANXA6,HLA-E,DAP,DNAJB2,WDR13,EIF3D,GNE,FLOT1,GYG1,USP48,MIEN1,RUFY1,GLRX3,CPNE3,SLC25A36,ANKRD28,RBM17,CSDE1,SLC31A1,PSMD1,IARS,VMP1,TBC1D14,ZNRD1,CTDSP2,TMX1,PCBP2,RLIM,TXNL1,TRAFD1,PPIE,RPL6,FBXO9,EMP3,RXRB,RPL36,AHNAK,TWSG1,CEBPG,CRCP,PITPNA,FBXL3,PDCD4,SMARCD1,SNAPIN |
| 2.533e-04 | -8.28 | GO_MICROTUBULE_BASED_MOVEMENT | MSigDB lists | GO_MICROTUBULE_BASED_MOVEMENT | 193 | 48 | 17377 | 2626 |
KIF3B,DYNLL1,ACTR3,AP3M2,KLC1,KIF23,RACGAP1,KIF2C,RAB6A,AP3S1,IFT27,APP,KTN1,KIFC1,KIF5B,STARD9,RAB21,CDC42,AP3S2,KIF13B,KIF14,AP2B1,KIFAP3,KIF22,IFT46,DNAL4,DCTN1,KIF15,BICD2,WDR81,RHOT1,RAB1A,KIF11,RHOT2,TMEM201,BBS12,KIF2A,KIF18A,PCM1,KIF18B,MAP4,LRPPRC,SSNA1,NDE1,CLN3,AP2S1,DYNC1LI2,SNAPIN |
| 2.545e-04 | -8.28 | MORF_EIF4E | MSigDB lists | MORF_EIF4E | 81 | 25 | 17377 | 2626 |
KDM3B,IMMT,NUP188,HMGN4,IDH3A,NKRF,BMS1,LANCL1,CCNF,DDX39A,ABCF1,CDK11A,MFN2,TFAP4,TAF2,RAP1A,TPP2,PSMD3,PTPN7,CTR9,NUP62,ANP32E,CPSF4,HDAC2,NXT2 |
| 2.547e-04 | -8.28 | testis | COSMIC cancer mutations | testis | 742 | 145 | 17385 | 2587 |
ABCC10,CSNK2A1,MAPK14,EEF2K,CDK5,ABL2,NEK6,ATG3,PIK3R2,XRCC2,HADHB,SRPK2,USP34,PLK1,PLK3,NRAS,AKT2,VHL,PBK,NOL8,LRBA,TLK1,AURKB,STK17B,CHAF1A,MAP3K4,LIMK1,STK11,RNASEL,CHEK2,PTOV1,LIME1,EWSR1,MUT,DHPS,PRKAA1,TRIO,CDK13,ADCK5,EIF2AK4,PDXDC1,SRRT,JMY,MED10,DAPK1,ATP6V0A2,PHKG2,PABPC1,CSNK1G3,ABCC1,CIC,UHRF1BP1,MAP4K3,EIF2AK1,KRAS,PTTG1IP,MAP2K2,SLTM,MTR,DAPK3,MASTL,GNAS,DERL1,MBIP,RBM25,CDC27,SNAP23,MYO9A,MAP3K5,CDK2,UNC13C,NRBP1,CDKN2A,CHMP2A,TP53RK,CHERP,TRIP10,RAF1,RPS6KA1,SF3B1,URB2,EIF3D,SMARCA4,ATP6V1B2,PRKACA,LYN,TWF2,APP,CHD1,COMMD8,FLAD1,PRKD3,PDK2,ANKLE1,SP100,CCDC50,ATP2A2,CDK12,SCYL3,ADCY7,CCT2,BRD4,PSMA8,MAP4K4,PKMYT1,BUD13,TRIM28,RHBDF2,JAK1,CLK3,FASTK,HIPK2,STK38,PDCD11,MAPK1,SMAD4,PRPF4B,R3HCC1L,SCYL1,ATG2B,CSNK1A1,SCYL2,FOXO3,FGFR3,PTPN11,H2AFY,CAMK2G,MYO5A,GINS1,PDPK1,RPAP3,CSNK1G2,ASPM,NEK7,HAGH,MACF1,MARK2,BSDC1,MAPK3,NEIL3,MAPK6,WDR91,RPS6KC1,HRAS,HIPK3 |
| 2.553e-04 | -8.27 | Oncogene Induced Senescence | REACTOME pathways | R-HSA-2559585 | 32 | 14 | 10287 | 1696 |
CDKN2C,MDM2,ETS2,ERF,RPS27A,TFDP1,E2F1,E2F3,TFDP2,E2F2,MAPK1,ETS1,CDKN2A,MAPK3 |
| 2.553e-04 | -8.27 | Export of Viral Ribonucleoproteins from Nucleus | REACTOME pathways | R-HSA-168274 | 32 | 14 | 10287 | 1696 |
NDC1,NUP188,NUP210,RAE1,NUP107,NUP54,NUP62,NUP153,NUP155,NUP85,NUP58,SEH1L,AAAS,NUP205 |
| 2.556e-04 | -8.27 | DUT (deoxyuridine triphosphatase) | protein interactions | 1854 | 76 | 25 | 17029 | 2761 |
RAB11B,C19orf25,TKT,RPL38,CUL3,RAB1A,MCM2,SPR,STMN1,PLEKHF2,HINT1,CDC42,SPATA2,DUT,PRDX5,PPA2,PPP1R11,FKBP5,TAGLN2,PPP5C,PPA1,IMPA2,CFL1,FUBP1,GPX4 |
| 2.565e-04 | -8.27 | SET (SET nuclear proto-oncogene) | protein interactions | 6418 | 120 | 35 | 17029 | 2761 |
OTUD5,HSPH1,COX15,UGP2,MTERF1,RAC1,CTCF,CCNB1,APP,WDR48,TERF2IP,CDK5,SUB1,MDM2,GART,HUWE1,UCHL5,BANF1,ANP32A,FTSJ3,TERF2,FYTTD1,MCM2,TRIM28,MATR3,TARS,CHAF1A,PPP2CA,NUCB1,NAP1L1,HMGB2,CD81,CDK2,TERF1,FAF1 |
| 2.570e-04 | -8.27 | GSE1460_CD4_THYMOCYTE_VS_NAIVE_CD4_TCELL_ADULT_BLOOD_UP | MSigDB lists | GSE1460_CD4_THYMOCYTE_VS_NAIVE_CD4_TCELL_ADULT_BLOOD_UP | 188 | 47 | 17377 | 2626 |
IMMT,MAPRE1,SMAP1,C5orf30,MAPK14,STMN1,BIRC2,CMTM6,MYL6B,RGS1,COPB2,VAV1,INTS7,RIMS3,PPP4R1,RAD23B,UBA5,MSH2,DAPK1,TIMELESS,SEPT11,STRAP,PTPRK,ERMP1,RPRD1A,KLF10,TNFAIP3,WDR1,LDHA,ITM2A,LRRC1,DNAJA1,SOX4,CBFB,TTC33,CBX3,CORO1C,NEIL3,IARS2,PGRMC1,SIL1,SPCS3,CHEK2,SMAD1,HDAC2,FAF1,PDCD4 |
| 2.570e-04 | -8.27 | GSE46606_DAY1_VS_DAY3_CD40L_IL2_IL5_STIMULATED_IRF4MID_BCELL_DN | MSigDB lists | GSE46606_DAY1_VS_DAY3_CD40L_IL2_IL5_STIMULATED_IRF4MID_BCELL_DN | 188 | 47 | 17377 | 2626 |
UBL3,DAP,UBR2,GNE,SMC6,PTP4A3,MEF2A,TAF6L,RGS2,SLC12A9,SYNRG,ARID1B,TMEM179B,MAT2B,PRKD3,MTA1,PHF14,UBE3B,TUBGCP5,RTF1,MAP4K3,AMDHD2,WBP1,RHOT1,PRKRA,TTC33,ECH1,SMAP2,NCDN,NECAP2,RAB18,PON2,PDLIM1,DGCR8,RBL1,CERS6,MYO18A,EXOC4,WDR7,ATE1,CNOT6,RNASEL,EHD4,NGLY1,NUDT3,DDB1,PRPF4B |
| 2.570e-04 | -8.27 | GSE37416_0H_VS_3H_F_TULARENSIS_LVS_NEUTROPHIL_DN | MSigDB lists | GSE37416_0H_VS_3H_F_TULARENSIS_LVS_NEUTROPHIL_DN | 188 | 47 | 17377 | 2626 |
GGA1,TMEM41B,CERK,ZNF267,SLC35B2,FKBP2,RLF,PSEN1,CHD1,RGS1,TFRC,KIFC1,SUB1,BRPF3,ATP13A3,PPCDC,PIK3IP1,CABLES2,TFG,TIPARP,STRAP,AMPD2,ETV3,ELL2,ANKRD33B,WDR1,MAP4K4,LDHA,EMP3,PNPLA8,CHMP2B,SERP1,ABCF1,ARF4,PPP2CA,SEC31A,ATP1A1,SYNCRIP,FBXO28,MAGT1,MAFK,HPS5,TFDP1,MAPK6,ATP6V1C1,ZMIZ1,PDCD4 |
| 2.570e-04 | -8.27 | GSE39820_CTRL_VS_TGFBETA1_IL6_IL23A_CD4_TCELL_DN | MSigDB lists | GSE39820_CTRL_VS_TGFBETA1_IL6_IL23A_CD4_TCELL_DN | 188 | 47 | 17377 | 2626 |
MIF4GD,LUZP1,TRIP10,KCTD17,ARFIP2,TAF6L,FKBP2,CDIPT,RAB11A,RGS1,SAC3D1,USF1,UBE2Q2,NEK6,MED10,BANF1,RNASEK,YIF1B,RPN2,OGG1,KDELR1,CLPTM1,ZDHHC18,KAT7,DCAF8,WDR1,CCDC34,ARHGDIB,WDR81,USP22,MEN1,RAB1A,VDAC1,GFER,HAUS8,FBXO21,DAP3,ERGIC3,PIAS2,ADAM9,RUVBL2,WIPI2,EHD4,REEP4,ATP6V0E1,TUBB,VPS29 |
| 2.570e-04 | -8.27 | GSE20198_IL12_IL18_VS_IFNA_TREATED_ACT_CD4_TCELL_UP | MSigDB lists | GSE20198_IL12_IL18_VS_IFNA_TREATED_ACT_CD4_TCELL_UP | 188 | 47 | 17377 | 2626 |
OTUD5,C1orf74,HIVEP3,TRIM41,PRKCSH,PHB2,GPR89A,TBC1D13,AP1B1,IKBIP,PITHD1,GIT2,HMG20A,SPPL2A,SF3B2,PHTF1,CNPY4,IFT46,NAA35,KCNAB2,PREB,DDX28,TIMM8B,POLR2I,TCTEX1D2,TACC1,CIC,HELB,ZMYND11,MRS2,ATP6V0A1,CBFA2T2,GUF1,ARSK,NDRG3,TRAM2,DNAJC10,EIF4ENIF1,SERF2,CCDC6,SEL1L,RNF38,TCOF1,IDH3B,SMAD1,YWHAH,GPR89B |
| 2.570e-04 | -8.27 | GSE41867_DAY6_EFFECTOR_VS_DAY30_MEMORY_CD8_TCELL_LCMV_ARMSTRONG_DN | MSigDB lists | GSE41867_DAY6_EFFECTOR_VS_DAY30_MEMORY_CD8_TCELL_LCMV_ARMSTRONG_DN | 188 | 47 | 17377 | 2626 |
UBL3,ANKRD13D,FAM53C,SRSF6,CDT1,CERK,C5orf30,MYH9,SMC6,TOP2B,MXD4,CDK11B,PPP1R16B,PHC2,WDR44,RNFT1,RPL17,LPIN2,F2R,N4BP2,RLIM,RYBP,ELOVL5,CYTH1,ABHD2,NEK7,MCL1,MAP4K3,SRSF5,WBP1,ARSK,TOLLIP,EML4,SFXN5,BSDC1,PHF6,GIGYF1,MKNK1,UAP1,TXNDC16,NRM,CAB39,WIPI2,FAU,TOB1,HIGD2A,PDCD4 |
| 2.570e-04 | -8.27 | GSE20715_0H_VS_6H_OZONE_LUNG_UP | MSigDB lists | GSE20715_0H_VS_6H_OZONE_LUNG_UP | 188 | 47 | 17377 | 2626 |
H2AFZ,PARP12,ST13,DYNLL1,MAGED1,RGS2,LYN,HAUS2,LMNA,CDKN2C,GLIS2,DAD1,SIVA1,SSBP3,AP1M1,AKR1B1,ARHGEF2,ANP32A,NDUFB9,TAGLN2,DNMT1,MTX2,CAMK2G,PRPF19,SEC61B,TSPYL4,RPL6,ILF3,RABIF,CBFA2T2,MRPS14,APPL1,POLR2A,MYO1F,YIF1A,UTP20,AMZ2,TRIM47,PDLIM1,FAM110A,TPP2,CSNK1G1,NUP62,TCOF1,C11orf1,RPS26,MRPL3 |
| 2.570e-04 | -8.27 | GSE339_EX_VIVO_VS_IN_CULTURE_CD4CD8DN_DC_DN | MSigDB lists | GSE339_EX_VIVO_VS_IN_CULTURE_CD4CD8DN_DC_DN | 188 | 47 | 17377 | 2626 |
WSB2,KARS,MIF4GD,SRGN,LAMTOR3,CCNL2,OAT,BRIX1,SRXN1,FBRS,FKBP1A,SLC31A1,LHX8,LPIN2,PELO,ANXA5,RNF19A,LRRC59,CCAR1,PDCL3,DNAL4,ABCC1,SOCS5,CDC5L,SAMD4B,IFRD1,C16orf72,RBX1,MAP4K4,EZR,PLEC,PTTG1IP,MAT2A,ARF4,EPB41,PFDN5,TSC1,ATP6V1D,ATP1A1,CCDC6,CORO1C,FASTK,ARNTL,ACTB,FAU,FBXL3,PSMC1 |
| 2.570e-04 | -8.27 | GSE360_CTRL_VS_B_MALAYI_LOW_DOSE_MAC_DN | MSigDB lists | GSE360_CTRL_VS_B_MALAYI_LOW_DOSE_MAC_DN | 188 | 47 | 17377 | 2626 |
WSB2,NPHP4,TSC2,UBN1,DAP,CUL1,CHKB,IFT27,BECN1,NDUFS7,CRKL,HNRNPA2B1,ARHGEF1,RRBP1,JOSD1,CLDND1,CYC1,MOB1A,CLTB,SLC35A1,PCBP2,TERF2,ZNF500,RNPS1,ADSL,GLO1,CADM1,KLF6,HAGH,ABCF1,PICALM,MATR3,MAPK3,CHAF1A,OPTN,CBX3,SH3BP5,KIF2A,CAT,HINT1,CLK3,DHX16,KHSRP,ST3GAL2,MRFAP1L1,ROCK1,NR2F2 |
| 2.570e-04 | -8.27 | GSE43955_10H_VS_60H_ACT_CD4_TCELL_WITH_TGFB_IL6_UP | MSigDB lists | GSE43955_10H_VS_60H_ACT_CD4_TCELL_WITH_TGFB_IL6_UP | 188 | 47 | 17377 | 2626 |
CCDC93,KLHL21,CDCA3,SMARCA4,CNTROB,ATP6V1B2,TWF2,MAP1LC3B,IFT27,REEP5,VPS25,LHX8,FOXN2,SLC26A2,LRRC59,FGFR1OP2,CDC5L,FDFT1,FYTTD1,ERCC1,TSPYL4,EMB,PSPC1,RPL6,WIPF1,WDR82,GORASP2,ARHGDIB,MPG,ELK1,PTTG1IP,OGFR,GFER,MAK16,RPSA,MAT2A,RPA1,EIF3K,MID1IP1,ETS2,ZHX1,CAPN7,SPRYD4,YY1,RRS1,EYA2,LONP2 |
| 2.570e-04 | -8.27 | GSE10273_LOW_IL7_VS_HIGH_IL7_AND_IRF4_IN_IRF4_8_NULL_PRE_BCELL_UP | MSigDB lists | GSE10273_LOW_IL7_VS_HIGH_IL7_AND_IRF4_IN_IRF4_8_NULL_PRE_BCELL_UP | 188 | 47 | 17377 | 2626 |
TMEM106C,GALK1,SKA3,C1orf112,EYA1,SUZ12,DBF4,OLA1,AGPAT1,SMARCA4,SLC29A1,TAF6L,PMF1,GGA2,SNN,STMN1,WDR48,KIFC1,TMEM69,PSMD1,KIF22,APOOL,TACC3,SLC25A1,POU2AF1,NASP,ASPM,OAF,WDR18,ZBED5,SLBP,NLN,EIF2A,ANLN,EPRS,MRPL55,CCDC86,FAM110A,RBL1,CDCA7L,MAPK6,CDCA5,PPM1G,ADAM9,HMGB2,GAS2,SSRP1 |
| 2.570e-04 | -8.27 | GSE360_CTRL_VS_L_MAJOR_MAC_UP | MSigDB lists | GSE360_CTRL_VS_L_MAJOR_MAC_UP | 188 | 47 | 17377 | 2626 |
GMFG,HLA-E,RPS6KA1,RAE1,UROD,RBM8A,SMARCA4,EZH1,SLC25A44,NDUFS7,NDUFS4,NFATC3,NDUFV1,MED8,NDUFA2,DPYSL2,CRAT,BANF1,ARHGEF1,MEA1,MSH2,PDS5B,CDC25B,CYC1,MARCH2,SMARCE1,ATP6V0D1,LDHB,PTPN18,TSTA3,USP10,GALK2,UBE4B,EIF4G2,HAGH,RFC2,MAK16,IRF5,CHAF1A,SRSF1,ALG3,PFDN5,AHNAK,DHX16,GLG1,LRPPRC,DDX52 |
| 2.570e-04 | -8.27 | GSE14908_ATOPIC_VS_NONATOPIC_PATIENT_HDM_STIM_CD4_TCELL_DN | MSigDB lists | GSE14908_ATOPIC_VS_NONATOPIC_PATIENT_HDM_STIM_CD4_TCELL_DN | 188 | 47 | 17377 | 2626 |
POLA2,UBL3,RRP15,MANBA,SRSF6,GPR89A,YTHDC2,CHIC2,USP39,CHAC2,INO80E,BRIX1,CRLF3,MRPL19,PAPOLA,LYAR,ERH,CLIC4,COQ4,SUV39H2,POP7,EXOSC1,ORAI1,ECD,RNF135,B3GALT6,NSDHL,MRPL12,POLR2D,TBRG4,ADSL,VDAC1,TXNL4A,LSG1,PSMB3,CCDC86,BIRC5,KBTBD7,RWDD4,PRMT7,AP1S1,RUVBL2,SMPD4,RBBP4,GPR89B,SSSCA1,PDF |
| 2.570e-04 | -8.27 | GSE19941_IL10_KO_VS_IL10_KO_AND_NFKBP50_KO_LPS_STIM_MACROPHAGE_DN | MSigDB lists | GSE19941_IL10_KO_VS_IL10_KO_AND_NFKBP50_KO_LPS_STIM_MACROPHAGE_DN | 188 | 47 | 17377 | 2626 |
BCCIP,DDX47,C19orf53,AGTRAP,TOR3A,UFC1,RBM8A,CIB1,MXD4,SLC35B2,AP3S1,PSEN1,RBM4,SAC3D1,MLX,MRPL34,PPP6C,BTF3L4,AKR1B1,PDCL3,FDFT1,AMPD2,NCK1,NSDHL,HSDL1,HTATIP2,NFATC2,ARHGDIB,GLO1,ODC1,API5,EML4,PRDX1,ECH1,RPA1,SDHB,ATP6V1D,PRDX3,CERS6,NIP7,DCK,PSMD8,OAZ2,PIAS2,RWDD4,ESYT2,RNF114 |
| 2.570e-04 | -8.27 | GSE46606_IRF4_KO_VS_WT_UNSTIM_BCELL_UP | MSigDB lists | GSE46606_IRF4_KO_VS_WT_UNSTIM_BCELL_UP | 188 | 47 | 17377 | 2626 |
CYTIP,IER2,ANKRD13D,GNPDA1,ARID2,CDT1,ANKH,TMEM109,MRPS26,MEF2A,MXD4,PIP4K2A,ANKRD39,PAIP2,RPL23A,ZKSCAN1,TBC1D14,MSH2,FNIP2,NCOA2,TMBIM1,ALDH9A1,GINS1,MND1,CYTH1,EID1,MAPKAPK3,MBLAC2,RPL6,DCLRE1C,HERPUD2,SOX4,KIF11,PDE3B,POLG2,EIF3H,CBX3,MTMR3,GNA12,OSBPL11,KIF18A,WDR11,TFDP1,UHRF2,TRIM32,TFDP2,PDCD4 |
| 2.570e-04 | -8.27 | GSE37301_MULTIPOTENT_PROGENITOR_VS_RAG2_KO_NK_CELL_UP | MSigDB lists | GSE37301_MULTIPOTENT_PROGENITOR_VS_RAG2_KO_NK_CELL_UP | 188 | 47 | 17377 | 2626 |
SEPHS2,RMND5A,ADD1,ANXA6,DHPS,SLC2A1,WDTC1,STARD7,RAB23,TM9SF3,USP48,OAT,XPO7,PRKACA,SDHA,XPR1,MAN1A1,USF1,APLP2,GRSF1,PPP6C,GLE1,EIF5,FAM3A,CLN6,MED22,SRPK2,CSTF1,FTL,CPOX,MAP4K4,SLBP,RRM2,WBP1,ODC1,POLG2,RPA1,DNAJC10,CAPN7,PGRMC1,PPP3R1,DDX5,DVL1,CDK2,MAPK1,RTN3,LONP2 |
| 2.572e-04 | -8.27 | AGGGCAG,MIR-18A | MSigDB lists | AGGGCAG,MIR-18A | 133 | 36 | 17377 | 2626 |
WASF2,CTDP1,SNX27,TRAF7,FAM53C,ENSA,UBE2Z,BCL2L1,MXD4,PHC2,CALM2,KDM2A,GOT2,AP3S2,RAD23B,ZFYVE27,CREB1,CITED2,ST8SIA2,STAT3,RPRD1B,TIMP2,HMGN5,TACC1,LRRC8A,PBRM1,ARID1A,CYFIP2,MAT2A,SERTAD2,EIF4ENIF1,OGT,E2F1,CRCP,YWHAZ,CSNK1D |
| 2.577e-04 | -8.26 | ECSIT (ECSIT signalling integrator) | protein interactions | 51295 | 111 | 33 | 17029 | 2761 |
IMMT,NDUFS1,ABCC10,STRN4,ABCB10,DNAJB1,FAM136A,PSEN1,APP,NDUFS7,RAD23A,FARSA,DECR1,EXOSC1,NDUFS8,MAVS,NDUFA3,CDC37,TIMMDC1,TMEM126B,NDUFB1,RHEB,DHX15,FAS,PI4K2A,CEP55,IARS2,ITGB1,NDUFS5,SMAD1,SMURF1,PPP2R2D,SMAD4 |
| 2.577e-04 | -8.26 | antigen processing and presentation of peptide antigen via MHC class II | biological process | GO:0002495 | 99 | 29 | 17256 | 2622 |
KIF3B,RAB7A,DYNLL1,DCTN2,KIF15,KLC1,KIF23,RACGAP1,ARF1,KIF2C,CAPZA2,AP1B1,KIF11,KIF2A,CTSL,SEC31A,CTSS,KIF18A,SEC24C,CAPZA1,DNM2,AP1M1,AP1S1,AP2B1,KIFAP3,KIF22,AP2S1,DYNC1LI2,DCTN1 |
| 2.577e-04 | -8.26 | antigen processing and presentation of peptide or polysaccharide antigen via MHC class II | biological process | GO:0002504 | 99 | 29 | 17256 | 2622 |
KIF3B,RAB7A,DYNLL1,DCTN2,KIF15,KLC1,KIF23,RACGAP1,ARF1,KIF2C,CAPZA2,AP1B1,KIF11,KIF2A,CTSL,SEC31A,CTSS,KIF18A,SEC24C,CAPZA1,DNM2,AP1M1,AP1S1,AP2B1,KIFAP3,KIF22,AP2S1,DYNC1LI2,DCTN1 |
| 2.581e-04 | -8.26 | SMC1A (structural maintenance of chromosomes 1A) | protein interactions | 8243 | 143 | 40 | 17029 | 2761 |
IVNS1ABP,CHTF18,RAE1,CTCF,NUF2,IRF3,BLM,BECN1,ANKRD28,RPA2,MRPL50,SMC3,MSH2,PDS5B,GCC1,MSH6,SMC4,CDC5L,PRPF19,SAP30,PLK1,STAU1,BRD4,CUL3,SMC2,BRCA1,MCM2,KDM1B,STYXL1,SF3A2,POLR2A,RPA1,DERL1,POLE,NSMCE2,CDCA5,USP32,YWHAZ,CDK2,USP13 |
| 2.582e-04 | -8.26 | vacuolar membrane | cellular component | GO:0005774 | 415 | 88 | 18223 | 2701 |
RAB14,ABCC10,RRAGC,AP1B1,ATP6V1B2,MAP1LC3B,GNB2,CMTM6,CPNE3,GLMP,PCYOX1L,ATP6V0B,NAPG,AP1M1,CLCN6,BRI3,AP2B1,RPN2,MARCH2,TMEM9,TMBIM1,SEH1L,DRAM2,ATP6V1G1,WDR41,CPNE1,MIOS,ATG9A,GOPC,RAB7A,ATP6V0A1,SLC17A5,RHEB,PLEKHF2,AHNAK,WDR11,SURF4,DDOST,WDR59,AP1S1,ATP6V0C,SCARB1,VPS4A,CLN3,AP2S1,STARD3NL,DNAJC5,ANXA6,CCZ1,MANBA,CDIP1,FLOT1,LAMTOR3,B4GALT1,MAN2B1,PSEN1,TMEM165,TMEM179B,SPPL2A,ZNRF2,VMP1,ATP6V0A2,TMEM8A,LPCAT1,ATP6V0D1,TPCN1,ABCC1,MFSD12,ACP2,GBA,WDR81,SPPL2B,NEU1,RMC1,SH3GLB1,PI4K2A,SCARB2,ATP6V1D,MAGT1,NSF,CCZ1B,SNAP29,LAMTOR4,CTSA,PSAP,ATP6V1C1,SNX14,SNAPIN |
| 2.594e-04 | -8.26 | ZHAN_MULTIPLE_MYELOMA_UP | MSigDB lists | ZHAN_MULTIPLE_MYELOMA_UP | 59 | 20 | 17377 | 2626 |
ZNF76,EWSR1,KAT2A,MAPKAPK3,ARID5A,ILF3,NKRF,ECH1,ALG3,FARSA,TSC1,GART,MTA1,NAP1L4,MVP,DNMT1,PURA,CAPN1,SSRP1,PTPRK |
| 2.594e-04 | -8.26 | GO_PEPTIDYL_LYSINE_METHYLATION | MSigDB lists | GO_PEPTIDYL_LYSINE_METHYLATION | 59 | 20 | 17377 | 2626 |
ASH1L,CXXC1,EHMT1,WDR82,RTF1,EZH1,WDR5,MEN1,KDM3A,DOT1L,TET3,IRF4,SUV39H2,SETD3,CAMKMT,ZNF335,OGT,CTR9,BEND3,ARID4A |
| 2.597e-04 | -8.26 | regulation of nucleotide-binding oligomerization domain containing signaling pathway | biological process | GO:0070424 | 8 | 6 | 17256 | 2622 |
ERBIN,BIRC3,TNFAIP3,BIRC2,HSPA1B,XIAP |
| 2.598e-04 | -8.26 | CASP8 (caspase 8) | protein interactions | 841 | 176 | 47 | 17029 | 2761 |
CASP6,TSC22D3,XIAP,VPS45,NSD3,BCL2L1,SNRPD3,BLM,CDK11B,MAP1LC3B,PSEN1,BIRC2,APP,BCAP31,PARK7,CFLAR,RB1,PTEN,HDAC7,GMEB1,CDKN1B,YBX1,BCL2,MAP3K14,PDIA6,RYBP,USO1,RHOA,BIRC3,TNFAIP3,VHL,CUL3,EZR,TOPORS,PLEC,PICALM,CDK11A,FADD,MAPK3,OPTN,FAS,ATAD2,CHD3,TICAM1,COPS6,MAPK1,FAF1 |
| 2.598e-04 | -8.26 | HIF1A (hypoxia inducible factor 1 subunit alpha) | protein interactions | 3091 | 176 | 47 | 17029 | 2761 |
MAX,UBXN1,MED13L,CSNK2A1,SMARCA4,DNAJB1,UBE2I,ZNF518A,RB1,MDM2,SHC1,HDAC7,MTA1,RAD23B,NSFL1C,BCL2,PTGES3,CITED2,STAT3,NCOA2,RHOBTB3,SEPT9,RBX1,VHL,NLN,BRCA1,EAF2,PKM,KDM3A,TRIM28,MAPK3,DAP3,HSPA4,MAFK,ARNTL,MED15,H2AFX,USP20,NCOA1,RUVBL2,MAPK1,SAT2,CAPN1,FAF1,CDKN2A,HDAC2,EGLN1 |
| 2.600e-04 | -8.25 | WANG_CISPLATIN_RESPONSE_AND_XPC_DN | MSigDB lists | WANG_CISPLATIN_RESPONSE_AND_XPC_DN | 219 | 53 | 17377 | 2626 |
SEPHS2,CDC40,UGP2,TRIP10,TSC22D3,BTN3A1,PPP3CB,CDIPT,TWF2,PSEN1,PAIP1,HERC3,CAPN2,ADD3,SP100,GRSF1,EFTUD2,TANK,PTPN11,ARHGEF2,ATG13,MRPL40,MAML1,CNPY3,CSNK1G3,EBAG9,TMEM115,ACP2,KLF10,HMGN4,TLK1,KIAA0930,PARP4,RFXANK,CUL3,EIF3G,TAF2,MAN2A2,SDHB,VEZF1,TSC1,ZNF317,FNTA,PDLIM1,CLK3,STAT1,LPCAT4,SSNA1,TCOF1,ATP6V1C1,HIPK3,IFI16,DDX52 |
| 2.601e-04 | -8.25 | regulation of G1/S transition of mitotic cell cycle | biological process | GO:2000045 | 177 | 45 | 17256 | 2622 |
UBE2E2,KMT2E,CDK2AP2,CCNB1,CNOT11,CDC73,CNOT3,RFWD3,CDKN2C,RPA2,RB1,PCNA,MDM2,PTEN,CENPJ,KIF14,FBXO7,GTSE1,BRD7,CDKN1B,BCL2,ECD,CNOT6L,CTDSP2,CARM1,PLK3,ADAM17,PRKDC,BTG2,CDC6,SOX4,PRMT2,CNOT9,RBL1,RPS27A,E2F4,TFDP1,E2F1,PML,CNOT6,PKD2,CHEK2,TFDP2,CDK2,CDKN2A |
| 2.603e-04 | -8.25 | REACTOME_NEP_NS2_INTERACTS_WITH_THE_CELLULAR_EXPORT_MACHINERY | MSigDB lists | REACTOME_NEP_NS2_INTERACTS_WITH_THE_CELLULAR_EXPORT_MACHINERY | 27 | 12 | 17377 | 2626 |
NUP188,NUP210,RAE1,NUP107,NUP54,NUP62,NUP155,NUP153,NUP85,SEH1L,AAAS,NUP205 |
| 2.603e-04 | -8.25 | REACTOME_REGULATION_OF_GLUCOKINASE_BY_GLUCOKINASE_REGULATORY_PROTEIN | MSigDB lists | REACTOME_REGULATION_OF_GLUCOKINASE_BY_GLUCOKINASE_REGULATORY_PROTEIN | 27 | 12 | 17377 | 2626 |
NUP188,NUP210,RAE1,NUP107,NUP54,NUP62,NUP153,NUP155,NUP85,AAAS,NUP205,SEH1L |
| 2.603e-04 | -8.25 | GO_HISTONE_H3_K4_METHYLATION | MSigDB lists | GO_HISTONE_H3_K4_METHYLATION | 27 | 12 | 17377 | 2626 |
TET3,ASH1L,CXXC1,SETD3,ZNF335,OGT,CTR9,RTF1,WDR82,BEND3,WDR5,ARID4A |
| 2.603e-04 | -8.25 | GNF2_MSH2 | MSigDB lists | GNF2_MSH2 | 27 | 12 | 17377 | 2626 |
GINS1,PCNA,NASP,RAD51AP1,U2SURP,LRPPRC,MSH2,RRM1,FANCI,MSH6,SMC4,SUPT16H |
| 2.603e-04 | -8.25 | GSE45365_WT_VS_IFNAR_KO_CD8A_DC_MCMV_INFECTION_UP | MSigDB lists | GSE45365_WT_VS_IFNAR_KO_CD8A_DC_MCMV_INFECTION_UP | 183 | 46 | 17377 | 2626 |
COMMD10,NSMCE4A,PARP12,GORASP1,RAF1,CHCHD2,PLXNA1,MYO9B,SLC20A1,PRKACA,LYRM2,CNOT3,FKBP1A,ZNF75D,ATP2A2,RAB4A,TNPO3,EIF5,NUP85,FTSJ3,LUC7L2,ALDH9A1,KDELR1,SOCS5,AMPD2,MLEC,BRD4,WBP2,MAP7D1,ARID1A,BICD2,SRSF5,FKBP3,MAP2K2,MYO1F,HGS,IDE,POLR2J,OAZ2,COX8A,STAT1,SH3GLB2,CENPT,CBX4,CAPN1,SSRP1 |
| 2.603e-04 | -8.25 | GSE3982_NEUTROPHIL_VS_CENT_MEMORY_CD4_TCELL_DN | MSigDB lists | GSE3982_NEUTROPHIL_VS_CENT_MEMORY_CD4_TCELL_DN | 183 | 46 | 17377 | 2626 |
SLC12A7,CCNC,DHPS,GPBP1L1,SEC61G,ABCC10,CHD1L,MCCC1,STARD7,TIA1,GLUD1,NENF,SRRT,PSMD1,ADD3,COQ4,WDR44,ATIC,NOC2L,RPN2,CYC1,UBE3C,ALDH18A1,FAM86C1,ILKAP,SEH1L,LARS,MAPRE2,MRPL12,GTPBP4,PRPSAP1,FANCE,PDE3B,MAT2A,ZFR,RAD54B,RPA1,FBXO21,CDCA4,HSPBP1,BRWD1,HINT1,TPP2,ERGIC3,CD81,TUBB |
| 2.603e-04 | -8.25 | GSE16522_MEMORY_VS_NAIVE_ANTI_CD3CD28_STIM_CD8_TCELL_UP | MSigDB lists | GSE16522_MEMORY_VS_NAIVE_ANTI_CD3CD28_STIM_CD8_TCELL_UP | 183 | 46 | 17377 | 2626 |
COMMD10,NAT9,ADD1,SCOC,CKLF,WDYHV1,GSPT2,TMX4,CHIC2,B4GALT1,PTP4A3,SUMF1,NIPA2,GLUD1,EIF1B,ZADH2,EXT2,HLA-A,FZD6,HERC3,RALB,IMPAD1,RAB4A,TECR,SPTSSA,MTX2,FGFR1OP2,EBAG9,ZFP64,FAM49B,RIT1,RHOB,DNAJC10,SCARB2,MKNK1,PLD3,UAP1,AGPAT2,NSF,CHCHD1,NFIL3,CTBS,VPS4A,RNASEL,TMEM14A,LRP8 |
| 2.603e-04 | -8.25 | GSE5589_WT_VS_IL10_KO_LPS_AND_IL10_STIM_MACROPHAGE_45MIN_UP | MSigDB lists | GSE5589_WT_VS_IL10_KO_LPS_AND_IL10_STIM_MACROPHAGE_45MIN_UP | 183 | 46 | 17377 | 2626 |
GCLM,GMFG,MAGED1,PTTG1,CENPF,TKT,CERK,KIF23,PPP3CB,BCL2L1,GGA2,CRLF3,CPNE3,WWP2,ANKRD28,TNS3,KIF13B,CNN2,CITED2,CLN6,MTPN,TPCN1,TERF2,PPT1,ERLIN1,SLC16A7,RNPS1,HSDL1,FRAT2,LRP5,GLO1,USP22,CADM1,SHCBP1,NEU1,TMEM184C,SGSH,WAS,CEP55,C4orf46,ACAT1,MAP3K5,CDK2,GEN1,YWHAH,LRP8 |
| 2.603e-04 | -8.25 | GSE1432_1H_VS_24H_IFNG_MICROGLIA_DN | MSigDB lists | GSE1432_1H_VS_24H_IFNG_MICROGLIA_DN | 183 | 46 | 17377 | 2626 |
USP7,DDX47,NSMCE4A,MAX,CYLD,HLA-E,UBR2,TAP1,TMEM109,CUL1,BTN3A1,PRPF39,GGPS1,CRLF3,LYN,MAT2B,SLC31A1,SMC3,RALB,ATG3,RBM34,DNAAF2,GRSF1,TAP2,PTGES3,MVP,DNMT1,RPAP3,RHOBTB3,LAP3,DENND1B,USP10,PSMB9,GUF1,FADD,RHBDF2,FAS,OSBPL11,FNTA,PRPS2,STAT1,VPS4A,SMURF1,APOL2,RNF114,TMEM131 |
| 2.603e-04 | -8.25 | GSE3982_EOSINOPHIL_VS_NEUTROPHIL_DN | MSigDB lists | GSE3982_EOSINOPHIL_VS_NEUTROPHIL_DN | 183 | 46 | 17377 | 2626 |
CDS2,FEZ2,REPS2,RPS6KA1,B4GALT5,FAM53C,KIAA0232,AGPAT1,TKT,ZNF107,ZFYVE21,B4GALT1,SNN,DUSP22,CHD1,GSTK1,ZNF473,SP100,CD3EAP,NAA50,CNN2,MAP3K14,TALDO1,TMEM8A,CNPY3,STAT3,ABCC5,TRIM8,TNFAIP3,KIAA0040,PFKFB3,MCL1,UBE4B,SF3A2,SH3GLB1,MAPK3,HLA-B,PPP2R5A,OSBPL8,NFIL3,CTBS,STAT1,PML,PITPNA,RTN3,CWC25 |
| 2.603e-04 | -8.25 | GSE16385_ROSIGLITAZONE_VS_UNTREATED_IFNG_TNF_STIM_MACROPHAGE_DN | MSigDB lists | GSE16385_ROSIGLITAZONE_VS_UNTREATED_IFNG_TNF_STIM_MACROPHAGE_DN | 183 | 46 | 17377 | 2626 |
BCL2L12,PRKAB1,LIME1,GNPNAT1,PRKCSH,RAE1,TRIM11,FLOT1,UBE2Q1,CHKB,UBE4A,INO80E,COMMD5,PABPC4,WDR48,C1GALT1,SAR1A,PPME1,AKAP8,BDH1,PPIL2,TTC4,CORO1A,PIK3IP1,NSUN4,FGFR1OP2,SRSF10,STAU1,SIGMAR1,GALC,RNF25,RFXANK,NUP155,COMMD4,NDRG3,ECH1,ARHGAP15,NECAP2,ELMO1,WIPI2,GPI,PPP5C,NRBP1,ZNF146,DYNC1LI2,RNF114 |
| 2.603e-04 | -8.25 | GSE17721_PAM3CSK4_VS_GADIQUIMOD_24H_BMDC_DN | MSigDB lists | GSE17721_PAM3CSK4_VS_GADIQUIMOD_24H_BMDC_DN | 183 | 46 | 17377 | 2626 |
CDS2,SYS1,MRPS2,DHPS,UBR2,RHOC,TOR3A,ACTR3,TAP1,PCSK7,TBC1D13,RAB6A,UBE2I,PSEN1,RBM17,SEC11A,RRN3,MDM2,ATG3,GRSF1,TPST1,DNM2,RBM3,RNF135,PDIA6,SGCB,SAP30,SLC39A9,SNX2,MAP4K3,CYFIP2,RAB22A,SERP1,MATR3,NMT2,HLA-B,PEX5,PDLIM1,DCK,FAM3C,SOCS4,IMPDH1,CHMP4B,RGL1,SMNDC1,RNF114 |
| 2.610e-04 | -8.25 | MODULE_321 | MSigDB lists | MODULE_321 | 109 | 31 | 17377 | 2626 |
GCLM,DEPDC1,CREG1,ACSL3,LDHA,MYH9,LRRC8A,PTTG1IP,ITGB5,KLF6,FAS,PRNP,CAPN2,APLP2,ASAP2,SHC1,NEK6,TWSG1,CORO1C,GMEB1,FAM3C,NFIL3,ITGB1,ADAM9,ANXA5,FKBP5,CNN2,PDXK,EHD4,CBX4,DDX42 |
| 2.627e-04 | -8.24 | CCDC22 (coiled-coil domain containing 22) | protein interactions | 28952 | 89 | 28 | 17029 | 2761 |
CPNE1,CCDC93,COMMD10,RPRD1A,PSPC1,CUL3,CUL1,PSMG1,COMMD5,XPO7,CYFIP2,COMMD6,COMMD4,COMMD8,SPAG5,SH3GLB1,DECR1,PCM1,VPS26C,HPS5,RTCB,MIA2,VIPAS39,CEP63,UBE2M,ABI1,PFKP,VPS29 |
| 2.627e-04 | -8.24 | CEP89 (centrosomal protein 89) | protein interactions | 84902 | 89 | 28 | 17029 | 2761 |
MOB4,SAMD4B,FGFR1OP,NPHP4,LUZP1,CCDC138,MYH9,SLC25A12,ADSL,HAUS4,ATG2B,SIRT2,PMF1,GAR1,ERC1,HAUS2,MARK2,HAUS8,ANKRD26,DLG5,PCM1,CCDC14,KIF14,CEP55,TXLNA,GPATCH1,TP53BP2,YWHAH |
| 2.631e-04 | -8.24 | nuclear membrane | cellular component | GO:0031965 | 304 | 68 | 18223 | 2701 |
NDC1,TOR1AIP1,TMEM109,TMEM97,BCL2L1,MRPL19,PRNP,ANKLE1,AHCTF1,NUP210,UTP18,INTS1,NUP107,TNPO2,TRA2B,NUP153,RBM15,SENP1,CPNE1,TOR1AIP2,NUP155,ERBIN,NUTF2,TXNL4A,TMEM201,CERS6,STAT6,NRM,SMAD1,ZC3HC1,AAAS,INTS2,DNAJC2,NEMP2,DNAJB2,NUP54,BRAP,PSEN1,QSOX2,NUP205,LMNA,DTL,MLX,NDUFB4,EI24,TNPO3,YBX1,BCL2,GLE1,TNRC18,NUP85,RB1CC1,SIGMAR1,GTPBP4,RANGAP1,NPIPA1,MATR3,CBX3,LEMD2,PCM1,KPNA4,OSBPL8,NSMF,LRPPRC,AEN,NUP62,NUP58,IPO4 |
| 2.632e-04 | -8.24 | GSE17721_PAM3CSK4_VS_GADIQUIMOD_8H_BMDC_UP | MSigDB lists | GSE17721_PAM3CSK4_VS_GADIQUIMOD_8H_BMDC_UP | 178 | 45 | 17377 | 2626 |
DNAJC2,NDUFA5,DNAJC5,NUP188,SRSF6,TKT,OLA1,LAMTOR3,PSEN1,GLRX3,SLC20A1,MIEN1,METTL3,PDXDC1,GNB2,SPAG5,SRXN1,C1GALT1,SMC3,GOT2,BDH1,FAM89B,RPF2,PDCD2,AHCYL1,LMAN1,PDIA6,KCNAB2,SPSB3,ALDH9A1,NUDC,NOL12,CCT2,NXT1,POLR2G,EID1,GTPBP4,PLEC,PTTG1IP,ARPC1A,EIF3A,TMEM184C,PLD3,UPF1,QARS |
| 2.632e-04 | -8.24 | GSE39820_CTRL_VS_TGFBETA3_IL6_IL23A_CD4_TCELL_DN | MSigDB lists | GSE39820_CTRL_VS_TGFBETA3_IL6_IL23A_CD4_TCELL_DN | 178 | 45 | 17377 | 2626 |
COPA,SUCLG1,TRIP10,CXXC1,MRI1,GADD45G,CUTA,ARFIP2,TAF6L,CDIPT,NPLOC4,USP5,USF1,UBE2Q2,MLX,BANF1,FIZ1,YIF1B,RPN2,AHCY,LRRC59,STAT3,OGG1,IMPA2,KDELR1,NET1,DCAF8,WDR1,ARHGDIB,USP22,AMDHD2,EDEM2,MEN1,PTTG1IP,FANCE,GFER,HAUS8,FASTK,PITX1,ADAM9,WIPI2,RUVBL2,REEP4,ATP6V0E1,DEF6 |
| 2.632e-04 | -8.24 | GSE18791_CTRL_VS_NEWCASTLE_VIRUS_DC_8H_UP | MSigDB lists | GSE18791_CTRL_VS_NEWCASTLE_VIRUS_DC_8H_UP | 178 | 45 | 17377 | 2626 |
NDUFA5,TP53RK,GXYLT1,RRP15,URB2,MON1B,ZNRF3,IKBIP,PDCD7,BRIX1,TWF2,EDC3,WRNIP1,PCYOX1L,SUV39H2,DNAAF2,PHF14,XPA,ANP32A,PRADC1,TNRC18,TSHZ1,ZNF559,MRPL12,UTP15,MRPL43,ADSL,FRAT2,THNSL1,C9orf40,GAR1,ARF4,IRF5,RPA1,DDX23,FBXO21,IDE,TMEM168,WNT5B,KBTBD7,FAM126A,SSNA1,TRIM32,OSGEPL1,GEMIN7 |
| 2.632e-04 | -8.24 | GSE27786_LSK_VS_CD4_TCELL_DN | MSigDB lists | GSE27786_LSK_VS_CD4_TCELL_DN | 178 | 45 | 17377 | 2626 |
DDX58,UBL3,CHMP2A,NSMCE4A,GXYLT1,RAF1,TAP1,ACAP1,CTCF,CHCHD2,AGPAT3,SIRT2,AGFG1,MYO9B,ASXL2,RPL23A,TMEM179B,CAPN2,RB1,RAP1A,VASP,MLX,PPIG,JAZF1,PPCDC,AKR1B1,GLTP,ABI1,KCNAB2,PHF20L1,ANKRD37,CRNKL1,ESYT1,LY6E,HERPUD2,NDRG3,NECAP2,PPP2R5A,JAK1,CLK3,GLG1,TBPL1,NLRC5,ROCK1,BRD9 |
| 2.647e-04 | -8.24 | GO_CELL_CYCLE_ARREST | MSigDB lists | GO_CELL_CYCLE_ARREST | 143 | 38 | 17377 | 2626 |
PRKAB1,SART1,TSC2,PRKAA1,LAMTOR3,CUL1,RRAGC,NOTCH2,EIF2AK4,JMY,PRNP,CDKN2C,DST,RB1,PA2G4,MSH2,CDKN1B,MCPH1,MLST8,TGFB1,PPP1R9B,CDC123,CUL3,TBRG4,MACF1,EIF4G2,RBM38,RHEB,MFN2,TSC1,PPM1G,PML,CAB39,STK11,PKD2,GAS2,HRAS,CDKN2A |
| 2.650e-04 | -8.24 | soft_tissue-fibrous_tissue_and_uncertain_origin-malignant_fibrous_histiocytoma-pleomorphic_sarcoma | COSMIC cancer mutations | soft_tissue-fibrous_tissue_and_uncertain_origin-malignant_fibrous_histiocytoma-pleomorphic_sarcoma | 35 | 14 | 17385 | 2587 |
KIF5B,RB1,EWSR1,NRAS,NF1,PTEN,SF3B1,ETV6,STK11,KRAS,FUS,SMAD4,HRAS,CDKN2A |
| 2.655e-04 | -8.23 | GSE46468_LUNG_INNATE_LYMPHOID_CELL_VS_SPLEEN_CD4_TCELL_UP | MSigDB lists | GSE46468_LUNG_INNATE_LYMPHOID_CELL_VS_SPLEEN_CD4_TCELL_UP | 173 | 44 | 17377 | 2626 |
HECA,PNISR,TRERF1,RPS6KA1,ACAP1,ASAH1,TCF19,ZNF518A,SDHA,HEATR5B,SAC3D1,TMEM179B,LIN9,ZNF449,TBC1D14,AKR1B1,KIF22,CNPY3,GPD1L,SAP30L,SLC35A1,KDELR1,ATP6V1G1,CPNE1,KDM3B,FAM172A,ZNF500,KAT7,EMB,MRPL43,FBXO9,EIF2AK1,CBFA2T2,ARSK,TAZ,ARHGAP15,SMAD2,EXOC4,ACAT1,TMEM101,HEXA,PURA,ATMIN,ANXA11 |
| 2.660e-04 | -8.23 | GO_REGULATION_OF_NUCLEOCYTOPLASMIC_TRANSPORT | MSigDB lists | GO_REGULATION_OF_NUCLEOCYTOPLASMIC_TRANSPORT | 214 | 52 | 17377 | 2626 |
DDX58,CYLD,TXN,PPP1R12A,CHERP,NF1,NUP54,RAB23,PPP3CB,PRKACA,MAPK14,RBM4,PARK7,CDK5,MDM2,SP100,PIK3R2,PTPN11,SRI,AXIN2,FAM89B,GTSE1,MDFIC,NUP153,MAVS,OGG1,ZC3H3,TGFB1,PPP3CA,RHOA,NUDT4,RANGAP1,BRCA1,NUTF2,SOX4,TRIM28,PRDX1,IWS1,AKAP1,KEAP1,KPNA1,TONSL,AXIN1,PPP3R1,NUP62,PKD2,ZNF268,PARP10,SMAD4,AAAS,FAF1,CDKN2A |
| 2.667e-04 | -8.23 | U2-type prespliceosome | cellular component | GO:0071004 | 17 | 9 | 18223 | 2701 |
SNRPB,LUC7L3,SF3B1,SNRPG,PRPF39,SNRNP70,LUC7L,SF3A2,LUC7L2 |
| 2.667e-04 | -8.23 | SMN-Sm protein complex | cellular component | GO:0034719 | 17 | 9 | 18223 | 2701 |
GEMIN6,GEMIN5,DDX20,GEMIN4,SNRPG,SNRPD3,STRAP,SNRPB,GEMIN7 |
| 2.669e-04 | -8.23 | GO_NEGATIVE_REGULATION_OF_CELLULAR_CATABOLIC_PROCESS | MSigDB lists | GO_NEGATIVE_REGULATION_OF_CELLULAR_CATABOLIC_PROCESS | 148 | 39 | 17377 | 2626 |
ZNF207,FEZ2,PHF23,KDM4A,DAP,UBXN1,CENPF,CSNK2A1,SECISBP2,SIRT2,BCL2L1,PSEN1,PARK7,MAD2L2,TBC1D14,BCL2,STAT3,SENP1,PABPC1,RNF5,PDCL3,PLK1,UBQLN4,TIMP2,PBK,TSC1,CHMP4A,GOLGA2,TAB2,LRPPRC,PML,CHMP4B,CLN3,SNRNP70,TOB1,TERF1,CDKN2A,SVIP,EGLN1 |
| 2.683e-04 | -8.22 | GCM_MAP4K4 | MSigDB lists | GCM_MAP4K4 | 163 | 42 | 17377 | 2626 |
WSB2,UBL3,SNX27,GORASP1,ADO,SIRT2,LANCL1,DCUN1D4,ZNF275,CRKL,NAPG,MTMR4,PPIG,IL6ST,GLTP,CLDND1,AHCYL1,ZNF710,SAP30L,PACS2,KDM3B,CLCN3,PHF10,ZNF84,TSPYL4,MAP4K4,WBP2,LRRC8A,MACF1,RAB22A,SH3GLB1,DDX17,FBXO21,EIF4ENIF1,GOLGA7,HIPK2,OAZ2,SLAIN1,PREPL,MYO9A,ATMIN,DYNC1LI2 |
| 2.685e-04 | -8.22 | Cleavage of Growing Transcript in the Termination Region | REACTOME pathways | R-HSA-109688 | 71 | 24 | 10287 | 1696 |
SRSF11,FYTTD1,CDC40,SARNP,THOC1,SNRPB,SRSF6,RBM8A,RNPS1,SLBP,SRSF5,SNRPD3,DDX39A,SYMPK,SRSF1,PAPOLA,ZNF473,EIF4A3,SRSF4,SNRPG,SRSF3,CHTOP,CPSF4,CSTF1 |
| 2.685e-04 | -8.22 | RNA Polymerase II Transcription Termination | REACTOME pathways | R-HSA-73856 | 71 | 24 | 10287 | 1696 |
SRSF11,FYTTD1,CDC40,SARNP,THOC1,SNRPB,SRSF6,RBM8A,RNPS1,SLBP,SRSF5,SNRPD3,DDX39A,SYMPK,SRSF1,PAPOLA,ZNF473,EIF4A3,SRSF4,SNRPG,SRSF3,CHTOP,CPSF4,CSTF1 |
| 2.686e-04 | -8.22 | GSE13547_CTRL_VS_ANTI_IGM_STIM_BCELL_12H_DN | MSigDB lists | GSE13547_CTRL_VS_ANTI_IGM_STIM_BCELL_12H_DN | 158 | 41 | 17377 | 2626 |
SEPHS2,BCCIP,RRP15,SUCLG1,RAB23,CRLF3,PCBP1,HDDC2,JAKMIP1,RBM17,DDX56,BDH1,AXIN2,EI24,RPL19,PIK3IP1,FBL,MRPL21,EEF1D,CSTF1,RPL29,RNASEH2C,EMB,TUFM,PSMG1,EIF3G,CLNS1A,EIF3H,SMAP2,RPL36,PFDN5,PDLIM1,ACYP1,PRDX3,NRM,RPLP1,PRMT7,ACADM,VPS4A,CHID1,EYA2 |
| 2.688e-04 | -8.22 | USB1 (U6 snRNA biogenesis phosphodiesterase 1) | protein interactions | 79650 | 29 | 13 | 17029 | 2761 |
SNX27,SNRNP200,CDC40,XAB2,PPIE,BUD31,CRNKL1,CSNK2A1,GPATCH1,AQR,SMAD4,PRPF19,CDC5L |
| 2.688e-04 | -8.22 | PDE12 (phosphodiesterase 12) | protein interactions | 201626 | 29 | 13 | 17029 | 2761 |
PGGT1B,STAT6,WDR4,RAD23B,CUL3,CHCHD2,ADSL,CUL1,BRCA1,DNAJB1,UBQLN2,PDLIM5,NPLOC4 |
| 2.690e-04 | -8.22 | MRPL10 (mitochondrial ribosomal protein L10) | protein interactions | 124995 | 72 | 24 | 17029 | 2761 |
MRPL9,MRPL42,MRPL39,MRPL12,MRPL43,ILF3,MRPL16,USP22,MRPL19,APP,MRPL50,MRPL2,MRPL55,MRPL27,MRPL34,MRPL40,MRPL48,PREPL,MRPL11,MRPL21,MRPL13,MRPL3,MRPL32,MRPL57 |
| 2.690e-04 | -8.22 | PFAS (phosphoribosylformylglycinamidine synthase) | protein interactions | 5198 | 72 | 24 | 17029 | 2761 |
CHERP,VHL,XIAP,ADSL,RABIF,EIF4H,ABHD14A,BZW2,EPB41,MAT2B,FLAD1,GNAS,HLA-B,GART,PDCD10,KEAP1,TFE3,YWHAZ,PPP6R3,EIF5,NIPSNAP2,PABPC1,CAPN1,LDHB |
| 2.690e-04 | -8.22 | CHRNA9 (cholinergic receptor nicotinic alpha 9 subunit) | protein interactions | 55584 | 72 | 24 | 17029 | 2761 |
TMUB1,PBXIP1,TMEM39A,PPP1R15B,POLR3GL,SLC12A9,PDE3B,LCLAT1,DDRGK1,GOLM1,ANKRD10,KIF5B,LEMD2,NUS1,TIMM29,TMEM268,FUT8,CISD2,MAVS,FAM76B,METTL9,DNAJC30,LRRC59,SNX14 |
| 2.690e-04 | -8.22 | TOP2B (DNA topoisomerase II beta) | protein interactions | 7155 | 72 | 24 | 17029 | 2761 |
UNK,COX15,SNRNP200,MTA2,SUMO2,SMARCA4,CTCF,TOP2B,SEPT7,UBE2I,MAPK3,RPA1,XRCC5,SUPT16H,RPA2,USF1,HNRNPR,PML,MSH2,BAZ1B,SMARCE1,IFI16,GPATCH4,HDAC2 |
| 2.707e-04 | -8.21 | RUTELLA_RESPONSE_TO_HGF_VS_CSF2RB_AND_IL4_DN | MSigDB lists | RUTELLA_RESPONSE_TO_HGF_VS_CSF2RB_AND_IL4_DN | 235 | 56 | 17377 | 2626 |
TXN,PPP1R12A,TRIP10,SUZ12,FAM129A,TCF3,TMEM97,ENSA,TIA1,MED13L,PTP4A3,NIT2,CREBL2,ARGLU1,TBC1D13,PLXNA1,RGS2,IL21R,PPP1R16B,CFLAR,CD59,IRF4,TNFAIP8,DPYSL2,GRSF1,MCM5,IL6ST,ANP32A,MAP3K14,TFG,MOB1A,ZDHHC18,CYTH1,BIRC3,CSRP1,CREG1,NET1,ACSL3,MAP4K4,CIRBP,NARF,HEBP2,MCL1,NFATC2IP,ZFAND5,STK17B,CYB5A,OPTN,JAK1,CERS6,WNT5B,GADD45B,LY75,NDE1,TRAF5,HDAC2 |
| 2.707e-04 | -8.21 | V$MYCMAX_03 | MSigDB lists | V$MYCMAX_03 | 235 | 56 | 17377 | 2626 |
POU3F2,DNMT3A,PPCS,SCYL1,GADD45G,TAF6L,RLF,STMN1,FOXO3,PABPC4,SSR1,FAM192A,TFAP4,CDKN2C,SMC3,SLC38A5,ARPC5,PRDM4,CITED2,FBXL19,ANKHD1,PABPC1,CCAR1,SOCS5,RBM15B,PHF20L1,LONRF3,C16orf72,SIGMAR1,ILF3,TOPORS,UBE4B,NDUFA7,PBRM1,MCM2,KRTCAP2,ODC1,PICALM,EIF3A,MAT2A,EPB41,RPA1,AKAP1,ADSS,GNAS,ALDH3B1,SEC23IP,SYNCRIP,BRD2,MRPL27,CTSA,RGL1,RBBP4,ATP6V1C1,HEXA,RAB3IL1 |
| 2.721e-04 | -8.21 | Fc-epsilon receptor signaling pathway | biological process | GO:0038095 | 123 | 34 | 17256 | 2622 |
RAC1,VAV2,CUL1,PPP3CB,LYN,PSMD9,VAV1,PSMD2,NFATC3,PSMA6,PSMD1,SHC1,PIK3R2,PDPK1,PPP3CA,NRAS,PSMA8,PSMB7,PSMA1,UBE2V1,KRAS,NFATC2,PSMB9,PSMB3,MAPK3,PSMC4,TAB2,RPS27A,PSMD8,PSMD3,PPP3R1,MAPK1,PSMC1,HRAS |
| 2.738e-04 | -8.20 | NINL (ninein like) | protein interactions | 22981 | 215 | 55 | 17029 | 2761 |
CEP170B,FGFR1OP,CYLD,EWSR1,MCM10,LUZP1,DCTN2,VPS45,PROSER3,RGS2,RCOR3,SCYL2,HAUS2,TUBGCP2,CNOT3,CRKL,DLG5,MZT2A,CCP110,CENPJ,KIF14,TXLNA,GTSE1,GPATCH1,TP53BP2,LRSAM1,GCC1,MICAL3,DCTN1,PLK1,CCDC138,TSPYL4,KAT7,ELOA,CAMSAP1,RCOR1,ANAPC2,BRCA1,TANC1,ERC1,DAPK3,GIGYF1,HSPA1B,CNOT9,MBIP,EIF4ENIF1,PCM1,CDC27,CCDC14,GPS2,CEP55,SASS6,ARRB2,ZNF598,DYNC1LI2 |
| 2.741e-04 | -8.20 | RBM19 (RNA binding motif protein 19) | protein interactions | 9904 | 40 | 16 | 17029 | 2761 |
NOL12,NIFK,UTP15,MEX3C,UTP18,RPS14,H2AFX,FBL,RRS1,ZC3H3,FTSJ3,IFI16,GPATCH4,BYSL,ZC3HAV1,SRPK2 |
| 2.741e-04 | -8.20 | POLK (DNA polymerase kappa) | protein interactions | 51426 | 40 | 16 | 17029 | 2761 |
KCTD17,TIA1,XPO7,MAK16,RBM4,RPA1,PCNA,RAD18,KLF16,STAT6,MSH2,RPAP1,DTD1,H3F3A,APOL2,MSH6 |
| 2.749e-04 | -8.20 | liver-other-adenoma | COSMIC cancer mutations | liver-other-adenoma | 17 | 9 | 17385 | 2587 |
GNAS,KRAS,NRAS,JAK1,STAT3,IL6ST,HRAS,AXIN1,CDKN2A |
| 2.757e-04 | -8.20 | CPSF6 (cleavage and polyadenylation specific factor 6) | protein interactions | 11052 | 98 | 30 | 17029 | 2761 |
UBQLN4,MAX,POLR2I,EWSR1,SUZ12,CUL3,RNPS1,CSNK2A1,JMJD6,SND1,CSNK1A1,TOLLIP,PARK7,LMNA,PAPOLA,CAND1,DDX17,WWP2,PA2G4,SAFB,NUP107,KHSRP,ANXA5,DDX5,FUS,CD81,SMURF1,MYL12B,LUC7L2,SRPK2 |
| 2.761e-04 | -8.19 | DDX3Y (DEAD-box helicase 3, Y-linked) | protein interactions | 8653 | 19 | 10 | 17029 | 2761 |
SMAD2,VHL,POC1A,ODF2,RPAP1,CRY2,MCM2,CCNB2,CD81,POT1 |
| 2.761e-04 | -8.19 | ISY1-RAB43 (ISY1-RAB43 readthrough) | protein interactions | 100534599 | 19 | 10 | 17029 | 2761 |
CDC40,PSMA6,XAB2,PPIE,BUD31,CRNKL1,AQR,SF3A2,PRPF19,CDC5L |
| 2.761e-04 | -8.19 | BRPF1 (bromodomain and PHD finger containing 1) | protein interactions | 7862 | 19 | 10 | 17029 | 2761 |
BRD2,MPHOSPH8,PBXIP1,KIF2C,ARRB2,KIF11,CDC73,PIP4K2A,MEAF6,XRCC5 |
| 2.761e-04 | -8.19 | Tsc1 (tuberous sclerosis 1) | protein interactions | 64930 | 19 | 10 | 17029 | 2761 |
DAP3,EIF4ENIF1,TSC2,JAK1,DNM2,LETMD1,EZR,SGF29,CCAR1,PDF |
| 2.763e-04 | -8.19 | primary lysosome | cellular component | GO:0005766 | 156 | 40 | 18223 | 2701 |
ADA2,DNAJC5,MANBA,HEXB,B4GALT1,MAN2B1,NHLRC3,PSEN1,CMTM6,CPNE3,TMEM179B,GNS,PA2G4,PSMD1,BRI3,LPCAT1,GM2A,CPNE1,FTL,CCT2,CREG1,ARHGAP45,HEBP2,TOLLIP,CCT8,DSN1,MAGT1,DDOST,SURF4,SNAP29,SNAP23,ACLY,IMPDH1,CTSA,ATP6V0C,PSAP,HEXA,MAPK1,TUBB,ANXA11 |
| 2.763e-04 | -8.19 | azurophil granule | cellular component | GO:0042582 | 156 | 40 | 18223 | 2701 |
ADA2,DNAJC5,MANBA,HEXB,B4GALT1,MAN2B1,NHLRC3,PSEN1,CMTM6,CPNE3,TMEM179B,GNS,PA2G4,PSMD1,BRI3,LPCAT1,GM2A,CPNE1,FTL,CCT2,CREG1,ARHGAP45,HEBP2,TOLLIP,CCT8,DSN1,MAGT1,DDOST,SURF4,SNAP29,SNAP23,ACLY,IMPDH1,CTSA,ATP6V0C,PSAP,HEXA,MAPK1,TUBB,ANXA11 |
| 2.771e-04 | -8.19 | transcription factor activity, RNA polymerase II transcription factor recruiting | molecular function | GO:0001135 | 8 | 6 | 17224 | 2647 |
MYBL1,SNAPC4,SGF29,TTF1,MYBL2,CDC5L |
| 2.773e-04 | -8.19 | DNA geometric change | biological process | GO:0032392 | 81 | 25 | 17256 | 2622 |
GINS1,RECQL,MTERF1,RBX1,HELB,TWNK,CHD1L,DHX9,BLM,MCM2,CHD1,GINS4,RAD54B,XRCC5,HNRNPA2B1,CHD3,RPS27A,XPA,RAD23B,HMGB2,RUVBL2,GTF2H2,POT1,PURA,DDB1 |
| 2.780e-04 | -8.19 | positive regulation of biological process | biological process | GO:0048518 | 5677 | 940 | 17256 | 2622 |
FGFR1OP,TSC2,ADD1,MAP3K7CL,HEXB,AGPAT1,XIAP,GLUD1,CCNL2,PPP1R16B,MIEN1,EDRF1,RBM4,FBXO22,EEF2K,CDK5,CALM2,USF1,PSMD1,NEK6,DNM2,FNIP2,ECD,ZNRD1,TIPARP,SENP1,MLST8,USP34,BAK1,PLK3,ERCC1,NRAS,AATF,GABPA,MCL1,TOPORS,NUTF2,DCUN1D5,SLC50A1,ARF4,STOML2,BRMS1,MID1IP1,SMAD2,RAD18,RPS27A,LIMK1,AXIN1,MYO18A,OGT,MLYCD,ATP6V0C,RNASEL,TRIM52,TFDP2,SMAD1,E2F2,OAZ1,PDCD4,SLC25A33,HIVEP3,CLSPN,GGA1,PHF23,RHOC,TRIO,DHX9,KCTD17,EZH1,EIF2AK4,PSMD9,APH1B,PARN,CDC73,LMNA,MCTS1,DDRGK1,TFAP4,DDX56,PDXP,SMC3,RIMS3,MEGF8,FBXO7,FOXN2,MYDGF,PABPC1,NUP85,PHKG2,NSUN4,CYFIP1,AGGF1,FOXK1,MAPKAPK3,RB1CC1,MTA2,TSPAN31,MYBL2,BCLAF1,SRSF5,CBFA2T2,ELK1,MATR3,RHOB,SCARB2,OSBPL11,FNTA,POLR2J,ETS2,DUSP3,CSK,SETD3,CNOT6,CFAP20,RUFY3,RNF139,ALS2,EGLN1,RHOG,ANKRD27,KARS,TRERF1,NQO1,IVNS1ABP,POC1A,CHD1L,ACTR3,ANK3,TPX2,MYH9,CREBL2,SLC35B2,DAZAP2,PRKACA,STMN1,STAM,CPNE3,ANKIB1,APP,RAB21,ATP2A2,SP100,MTA1,GMEB1,RNF19A,MAVS,ATF2,RBM15,CLN6,GPD1L,ZC3H3,RPRD1B,PDCL3,DCTN1,ADCY7,ENPP4,CPNE1,ULK3,SHOC2,PSRC1,POLR2L,KAT7,MAP4K4,WBP2,POLR2D,RNPS1,CIRBP,E2F3,PFKFB3,CDCA2,NUSAP1,GORAB,DNAJA1,MEF2D,RAB1A,TAZ,DDX17,TAF2,PPP2CA,NSMCE2,CORO1C,HIPK2,RPLP1,CBLN2,TICAM1,PPP5C,GEN1,LRP8,USP13,RPS2,SRSF6,ZFP91,HABP4,FLOT1,TRAK1,BTN3A1,ABHD14B,ATP5F1B,IP6K2,WDR5,HDGFL2,ETS1,SAPCD2,RPA2,ERH,PSMD2,PDCD10,ITGB8,HUWE1,PRDM4,ARHGEF1,GTSE1,GTF2H2,TPCN1,S100A6,PDPK1,STAU1,PPP3CA,TNFAIP3,JTB,LDHA,HEBP2,LLPH,ZP3,PICALM,CIP2A,RPA1,KEAP1,GPS2,WNT5B,PITX1,MAPK6,CAPN7,PML,HMGB2,PSAP,CD81,USF2,YWHAH,FAF1,SNAPIN,AGRN,THOC1,AAMDC,GPBP1L1,TRIM11,PPP1R15B,FAM129A,YTHDC2,CSNK2A1,NENF,S1PR2,SEC16A,BIRC2,TRIM65,FANCI,SSR1,CREM,PRNP,TET3,ABL2,DLG5,PCNA,GLIS2,IL6ST,ZNF639,ETV6,PIK3R2,XRCC2,ZFYVE27,MYBL1,MTPN,CCAR1,RYBP,CDC37,PLK1,SP3,EXOSC6,SEPT9,MIOS,RBX1,APH1A,MRPL12,EZR,CDC6,UBE2V1,LRP5,IL12RB1,EAF2,BRCA1,ANLN,PRKRA,ODC1,USP21,RHEB,OPTN,EPB41,DPYSL3,AGPAT2,E2F4,SOCS4,ADAM9,ACTB,PIEZO1,DVL1,BEND6,SINHCAF,POT1,C2CD5,NUMB,ZNF564,FUBP1,PHB2,NKD2,LAMTOR3,CTCF,CHCHD2,RACGAP1,CDK13,NCKAP1,PPP3CB,DOCK11,RLF,ASXL2,CNOT11,CRLF3,ARID1B,TNS3,SUB1,RB1,VASP,MLX,NUS1,CCP110,TIGAR,MBD2,SSBP3,XPA,ZNF746,ARL6IP1,CTR9,TIMELESS,MDFIC,RBM3,ICE2,MAML1,LRSAM1,TRAPPC9,AACS,ACSL3,LDB1,UTP15,KRAS,MAP4K3,RTF1,NFATC2IP,ICAM2,ARPC1A,EIF4G2,IRF5,PSMC4,RXRB,GOLGA4,PCM1,SYNCRIP,LAMTOR4,NLRC5,TBPL1,RUVBL2,ATP5F1A,BTBD10,RNF114,USP7,KCTD7,SART1,CYLD,TRAF7,FOXM1,DYNLL1,SUMO2,RRAGC,LYN,DUSP22,PCBP1,BCAP31,RAD23A,RPL11,VAV1,NRF1,PSMA6,MDM2,TNFAIP8,PIN1,PDCD2,TARDBP,CORO1A,LMAN1,AHCYL1,SPIDR,DVL2,PRPF19,PPIF,TIMP2,BIRC3,POLR2G,PPT1,PSMA8,RAB7A,BTG2,PPIE,SLC26A6,NFATC2,CHMP2B,USP36,SRSF1,ATP1A1,IDE,SCAP,RBL1,PSMD3,TIMM17A,PLGRKT,UHRF2,XRCC3,CHMP4B,NCOA1,H3F3A,SMAD4,PARD3,BCL2L12,SLC30A9,CTDP1,SMAP1,DAP,CDT1,AGO2,SMC6,HMGN3,NKRF,CSNK1A1,PAGR1,SCYL2,TFRC,PTPN2,HOMER1,IRF4,CTSS,SS18L1,PTGES3,POLR1B,RHOA,HMGN5,PRKDC,ARHGEF12,TRIM26,PDCD6,NEK1,BIRC5,TWSG1,TFE3,CDCA7L,E2F1,PKD2,RBPJ,TAF12,NR2F2,UBE2C,IFI16,TXN,ZNF496,H2AFZ,PDCD6IP,ADAM10,CXXC1,YTHDF3,CUL1,PLXNA1,CCNB1,UBE2I,SLC20A1,POLR3K,PARK7,GLMP,PA2G4,NOL11,FIZ1,CNPY4,AP2B1,TRA2B,CDC25B,TFG,DNMT1,SEH1L,CDC5L,KLF10,AKT2,MRNIP,DDX20,AURKB,USP22,SLC25A5,RFC2,CBFB,RAB2B,DOT1L,MAP3K4,HHEX,WAS,PSMD8,ITGB1,ARRB2,SLF1,TRAF5,ZMAT3,NMD3,HDAC2,SVIP,DDX58,PPIB,HSPH1,MAPRE1,LIME1,SCOC,DHPS,POLR2K,CHTF18,HLA-E,GADD45G,VAV2,PRKAA1,KIF23,B4GALT1,CYCS,NOTCH2,PSEN1,METTL3,CNOT3,JMY,WDR48,SPAG5,CFLAR,NDUFS4,FKBP1A,TMEM250,ARPC5,HDAC7,MSH2,DAPK1,RNF135,GNAI2,LPCAT1,EEF1D,TMED2,TERF2,SOCS5,EIF5A,WDR1,MFNG,PIP4K2C,KCTD20,EXOSC9,ARID1A,ADRB2,CYFIP2,FXR1,PTTG1IP,KDM3A,MAP2K2,SF3A2,CCT8,PSMB3,TWISTNB,FAS,XRCC5,DERL1,CAT,SERTAD2,HSPBP1,GOLGA2,NSF,RBMX,ACLY,PIAS2,ARAP1,CEBPG,PPP3R1,FAM83D,GPI,YY1,MAP3K5,RNF14,CDK2,ZC3HAV1,CDKN2A,DNMT3A,ATXN3,RWDD1,RPS6KA1,SF3B1,RAF1,SUZ12,EIF3D,GPR89A,RAC1,MAGED1,BCL2L1,CD320,EPM2A,MOAP1,TERF2IP,CRKL,CCNA2,SHC1,SIAH1,RALB,LPIN2,ADCY9,MRPS27,CDKN1B,TP53BP2,CDK12,TMBIM1,CFL1,ANKLE2,CCT2,CDKN2AIP,BRD4,RFC3,CDC123,TAOK1,CUL3,EDF1,PSMB9,ERC1,SERP1,TRIM28,SUPT16H,VEZF1,RAD51C,JAK1,PPP2R5A,HINT1,SAFB,H2AFX,STAT1,ATF6,TRIM32,BEND3,EYA2,CSNK1D,ATMIN,RHEBL1,POU3F2,NCOR2,PKP4,MECP2,TCF3,BABAM1,CBLL1,SECISBP2,BLM,RAB11A,FOXO3,MAD2L2,WWP2,GTF2F1,CCNK,ELP5,PTEN,CENPJ,PTPN11,PRC1,AXIN2,CARF,CITED2,CNOT6L,MAP3K14,CREB1,CNPY3,UBE2M,MSH6,NCOA2,KAT2A,LONRF3,DENND1B,NEK7,NET1,ILF3,RFXANK,TBRG4,ANAPC2,KCNQ1,MACF1,KLF6,MARK2,FADD,SH3GLB1,POLR2A,HGS,PRDX3,STX18,TFDP1,OAZ2,KHSRP,DDX5,ESPL1,PURA,DDB1,RORB,MIB2,ZBED3,CCNC,ZNF76,IER2,NPHP4,UBE2E2,PLXNC1,NOP2,HNRNPAB,NF1,KMT2E,UBE2Z,PTP4A3,SIRT2,UBQLN2,MAPK14,BECN1,ZNF804A,RAP1A,C18orf32,CDC42,EIF4A3,METTL14,SRI,AKR1B1,TCEA1,SLC35C2,CARMIL1,ARID4A,TRIM14,CARM1,SRPK2,ELOF1,COPS8,DEAF1,LARS,TRIM8,NCK1,VHL,SOX4,STK17B,ABHD5,PAF1,UBTF,PQBP1,CRCP,CAB39,BAZ1B,ZNF268,STK11,CHEK2,CLU,VPS4A,ROCK1,PSMC1,CAPN1,UBE2D3,NSMCE4A,PPP1R12A,TM9SF4,GORASP1,CIB1,TIA1,MEF2A,THRAP3,RGS2,EPHX2,SRRT,RHBDD1,APOPT1,LYAR,DTL,NFATC3,MED10,PYURF,FAM89B,ZNF335,BUD31,ORAI1,TENM3,KIFAP3,BCL2,YBX1,ZRANB1,ATP5IF1,POLR2I,ERLIN1,GBA,PSMA1,EIF2A,SEPT7,CCDC71L,DAPK3,ISG15,CAND1,GNAS,TSC1,NAP1L1,NSMF,NFIL3,CDCA5,NUP62,YWHAZ,DNPH1,ZFP90,EHD4,SNRNP70,NIPSNAP2,TOB1,N4BP2L2,SMARCD1,ADNP2,WASF2,TCF12,CHMP2A,PRKAB1,ASH1L,IFI27L1,CHERP,SMARCA4,PLAGL2,IRF3,TWF2,CHD1,PAIP1,MIEF1,USP5,HNRNPA2B1,RRN3,ANKLE1,BABAM2,CD3EAP,NVL,KIF14,AKAP8,CHTOP,F2R,ABI1,HTRA2,MOSPD1,CHP1,POU2AF1,CGAS,PGGT1B,RNF25,PSMB7,WIPF1,CADM1,EDEM2,PEF1,TOLLIP,RPS9,SURF4,TAB2,HNRNPR,STAT6,GADD45B,ARNTL,WDR59,CANT1,SCARB1,TMEM101,AKNA,SMURF1,MAPK1,ABCA1,TSPAN5,TMEM33,PDF,NAT14,MIF,DNAJC2,KIF3B,GOLPH3L,SH2D3A,EYA1,DBF4,KLF13,PAWR,DCUN1D4,PIP4K2A,FERMT3,FBXO5,KIF5B,FASTKD3,FGFR3,GRK2,CTNNBL1,PELO,TANK,NABP2,ZDHHC13,H2AFY,ARHGEF2,BRD7,ATG13,STAT3,TGFB1,ELOVL5,COA3,TELO2,DCAF6,ADAM17,HMGN1,FAM49B,ASPM,PSPC1,MIER1,ATP2C1,PRKAR1B,POLR3GL,PRMT2,MEN1,SYMPK,MAPK3,MFN2,TFEB,HSPA1B,CNOT9,CTSL,UPF1,ATAD2,PLAA,ELMO1,OSBPL8,KMT2B,ZMIZ1,HRAS,SLF2,TERF1 |
| 2.782e-04 | -8.19 | ATGTTAA,MIR-302C | MSigDB lists | ATGTTAA,MIR-302C | 230 | 55 | 17377 | 2626 |
INTS2,POU3F2,RAB14,IMMT,GGNBP2,MAPRE1,PPP1R12A,B4GALT5,SF3B1,WDTC1,ATP6V1B2,PCBP1,ARID1B,SPPL2A,CREM,HNRNPA2B1,ADD3,SUV39H2,PHF14,NUP153,SLC35A1,HDHD2,CGGBP1,SNX25,PHF20L1,GABPA,RAB7A,BTAF1,ATP2C1,MTMR6,SRSF5,FXR1,CYFIP2,MATR3,RHEB,CAND1,VEZF1,FBXO21,LUC7L3,PPA2,PPP3R1,VCPIP1,CBLN2,SAMD8,YY1,FBXL3,H3F3A,ZMIZ1,PPP5C,SMAD4,TOB1,CPEB2,NUMB,CSNK1D,TMEM33 |
| 2.782e-04 | -8.19 | WANG_PROSTATE_CANCER_ANDROGEN_INDEPENDENT | MSigDB lists | WANG_PROSTATE_CANCER_ANDROGEN_INDEPENDENT | 55 | 19 | 17377 | 2626 |
PPP1R12A,REPS2,ZNF84,RPLP2,BTG2,GADD45G,SDC2,TOP3A,FRAT2,MCL1,ITGB5,NMT2,HDDC2,DST,SGSH,RABGAP1L,DBI,SPCS3,PRPF19 |
| 2.789e-04 | -8.18 | endoplasmic reticulum | cellular component | GO:0005783 | 1852 | 326 | 18223 | 2701 |
TMED7,RAB14,PDCD6IP,TMEM203,ADAM10,PRKCSH,PIGQ,TMEM109,AGPAT1,TAP1,TGOLN2,IKBIP,PARK7,CYB5RL,CISD2,MARCH2,RNF26,TFG,SPTSSA,LRRC59,SRP72,BAK1,PGAP2,USO1,ATG9A,ICMT,MCFD2,RAB2B,PLEKHF2,STT3A,TMED10,RPS27A,SARAF,RRS1,RTN3,SVIP,PPIB,SEC61G,HLA-E,KCTD17,SLC35B1,TMED3,NOTCH2,APH1B,PSEN1,COPG2,NPLOC4,COPB2,DDRGK1,CD59,FKBP1A,RPN1,RNF121,LRRC8D,RNFT1,DAD1,PIGG,RTCB,PCYT2,MYDGF,LPCAT1,TMED2,APOL1,EEF1D,FDFT1,EIF5A,PIGT,CPQ,SIGMAR1,RB1CC1,PGS1,ERO1A,RDH10,MAN1B1,USF3,SSR2,MAP2K2,CYB5A,RDH11,DERL1,SEC31A,CAT,SCARB2,TXNDC16,ERGIC3,LPCAT4,VCPIP1,SAMD8,SMPD4,MAP3K5,RNF139,RHOG,ATXN3,CAST,ANK3,RAC1,VTI1A,SLC39A13,TMEM97,POMP,SLC35B2,BCL2L1,ADPGK,LCLAT1,KTN1,APP,CD320,RAB21,APLP2,ATP2A2,LPIN2,TAP2,ANKRD13C,CLN6,ANKLE2,SEC61B,ERMP1,ATP13A1,PKMYT1,TMEM147,DNAJA1,RAB1A,SERP1,SEC61A1,DDOST,CERS6,SEL1L,NCLN,MBOAT1,ATF6,AGPAT3,SDF2L1,POFUT1,REEP5,WRB,HLA-A,EBP,GOLM1,CAPN2,CRAT,AHSA1,OSTC,CNPY3,TMX1,PACS2,STAU1,KCNQ1,ARSK,PDE3B,RPL27A,SPPL2B,YIF1A,NUCB1,PLD3,KEAP1,MAGT1,WNT5B,DBI,STX18,PML,ASNA1,FAF1,ESYT2,PIGM,COPA,PPP1R15B,YTHDC2,MOGS,CDIPT,FKBP2,BECN1,SEC16A,RNF103,PRNP,SSR1,DST,NUP210,CDC42,THADA,RAB35,PHTF1,HADHB,SRI,ZFYVE27,TECR,LARS,DPM1,APH1A,NCK1,VHL,LRBA,PSMG1,LRP5,SUMF2,PITPNB,ESYT1,KRTCAP2,LSG1,RHEB,ALG3,TRAM2,AGPAT2,MIA2,CLU,PIEZO1,CLN3,RPS26,STARD3NL,PIGN,AGTRAP,DNAJB2,UBXN1,SDC2,CIB1,RAB6A,RHBDD1,NUS1,PYURF,VMP1,ARL6IP1,EI24,SLC27A4,KIFAP3,BCL2,PREB,KDELR1,TRAPPC9,ERLIN1,NSDHL,ACSL3,RPL6,UTP15,SYVN1,VKORC1,ZDHHC3,MOSPD3,GALNT2,SYNCRIP,ORMDL2,ZDHHC7,SIL1,CTSA,EHD4,TMEM14A,ECPAS,APOL2,PTDSS1,TMEM106C,CHERP,COPE,TMX4,CLCC1,EXT2,BCAP31,SEC11A,UBXN2A,SAR1A,RPN2,BCAP29,CYB5R1,AHCYL1,LMAN1,MINPP1,PDIA6,ABI1,HTRA2,CHP1,MOSPD1,ACSL5,UBQLN4,FAM172A,SLC26A6,TOR1AIP2,EDEM2,PEF1,RHBDF2,DNAJC10,ATP1A1,SURF4,HNRNPR,SCAP,UBXN2B,CANT1,REEP4,ABCA1,TMEM33,SLC30A9,CDS2,TOR3A,TMX3,SUMF1,DNAJB9,MAN1A1,SPPL2A,PTPN2,FGFR3,SEC24C,RRBP1,DUS2,SLC35B4,ZDHHC13,ANP32A,YIF1B,ATG13,CAMK2G,MYO5A,RNF5,B3GALT6,ELOVL5,ZDHHC18,MLEC,RHOA,WDR81,PNPLA8,MEN1,HSPA1B,LEMD2,HLA-B,RAB18,SEC23IP,PDCD6,OSBPL8,PGRMC1,PKD2,SPCS3,PLOD3 |
| 2.791e-04 | -8.18 | lung-carcinoma-mucoepidermoid_carcinoma | COSMIC cancer mutations | lung-carcinoma-mucoepidermoid_carcinoma | 78 | 24 | 17385 | 2587 |
EXOC3,NRAS,CHTF18,SF3B1,CHCHD2,KRAS,PRMT2,PRKRA,ITGB5,EML4,MFSD10,KIF5B,DST,ERV3-1,TMEM41A,CCDC6,TMEM99,LTN1,GEMIN4,TOP1MT,MVP,PDCD11,HRAS,CDKN2A |
| 2.791e-04 | -8.18 | REACTOME_SIGNALING_BY_ERBB4 | MSigDB lists | REACTOME_SIGNALING_BY_ERBB4 | 86 | 26 | 17377 | 2626 |
PDPK1,ADAM17,NRAS,TSC2,APH1A,RBX1,AKT2,RAF1,CUL1,KRAS,AKT1S1,PSEN1,APH1B,FOXO3,MAP2K2,MAPK3,MDM2,SHC1,PTEN,RPS27A,TAB2,CDKN1B,CREB1,MAPK1,HRAS,MLST8 |
| 2.795e-04 | -8.18 | MAPRE1 (microtubule associated protein RP/EB family member 1) | protein interactions | 22919 | 167 | 45 | 17029 | 2761 |
UNK,FGFR1OP,MAPRE1,CYLD,EWSR1,ADD1,LUZP1,KLHL21,DCTN2,TRIO,OLA1,KIF2C,SEC16A,PRKACA,APP,SPAG5,DST,CD59,CEP104,ADD3,RAB35,CAPZA1,CLTB,GNAI2,DCTN1,SPTAN1,SRPK2,COPS8,MAPRE2,WDR1,PSMA1,AURKB,PLEC,MACF1,ERC1,PCM1,KIF18B,AXIN1,QARS,PQBP1,STK11,YWHAZ,CDK2,TERF1,TUBB |
| 2.811e-04 | -8.18 | UBQLN1 (ubiquilin 1) | protein interactions | 29979 | 225 | 57 | 17029 | 2761 |
PPIB,UNK,CYLD,ATXN3,GNPDA1,DNAJB2,SRGN,UBXN1,UBQLN2,FKBP2,ATP6V1B2,PSEN1,STMN1,GIT2,APP,MIEF1,RAD23A,C12orf10,HERC3,RPN1,PSMD2,PSMA6,IL6ST,RAD23B,ORAI1,TARDBP,CYB5R1,PIK3IP1,AHCYL1,KDELR1,USP34,UBQLN4,PBXIP1,WBP2,UBE2V1,UBE4B,CLNS1A,ZMYM3,FAS,HGS,PDCD6,ITPRIPL1,PSMD3,RBMS1,SIL1,TICAM1,ZRANB2,TRIM32,KLHL42,SNRNP70,NDE1,UBE2C,SMURF1,NGLY1,NUP58,SSSCA1,ESYT2 |
| 2.811e-04 | -8.18 | TGCCTTA,MIR-124A | MSigDB lists | TGCCTTA,MIR-124A | 526 | 109 | 17377 | 2626 |
RHOG,RAB14,GLT8D1,TMEM184B,TMEM109,PLAGL2,MYH9,SLC35B2,USP48,MAPK14,LCLAT1,GIT2,JAZF1,SUCLG2,SEPT11,MTPN,SP3,ERMP1,BRD4,MKLN1,OSBP2,ERF,SREK1,WIPF1,SLBP,ICMT,CHMP2B,CBFB,SERP1,TRAM2,AHNAK,BRWD1,SURF4,RWDD4,OGT,RBMS1,GAS2,PDXK,TFDP2,RTN3,EYA2,DYNC1LI2,ATMIN,ANXA11,NXT2,MAPRE1,GGA1,SESTD1,SRSF6,MECP2,EYA1,TOR3A,TCF3,B4GALT1,KLF13,MYNN,ARGLU1,AKT1S1,RAB6A,GGA2,PSEN1,ETS1,RAB11A,CCDC28A,NPLOC4,LMNA,RAVER2,JAKMIP1,TMCC3,CAPN2,C1GALT1,SLC31A1,SLC1A4,VMP1,ARPC5,RRBP1,MEA1,ANXA5,ATP6V0A2,GLTP,CREB1,STAT3,SAMD4B,ELOVL5,ELL2,TACC1,SIGMAR1,DENND1B,RFFL,MTMR12,LRRC1,PTTG1IP,MACF1,ZDHHC3,PHF6,AKAP1,TPD52L2,OSBPL11,PDCD6,TMEM168,MAGT1,CCDC6,CSNK1G1,CEBPG,SLC16A1,ZRANB2,PPP6R2,PPP6R3,ESYT2 |
| 2.813e-04 | -8.18 | POLR2D (RNA polymerase II subunit D) | protein interactions | 5433 | 68 | 23 | 17029 | 2761 |
FTL,POLR2I,RPRD1A,POLR2G,POLR2L,POLR2K,DCTN2,ELOA,POLR2D,BRCA1,MCFD2,PSMB9,POLR2A,XRCC5,WWP2,GTF2F1,MED10,POLR2J,LIMK1,CTR9,RPRD1B,ASB6,SMARCD1 |
| 2.813e-04 | -8.18 | WDR12 (WD repeat domain 12) | protein interactions | 55759 | 68 | 23 | 17029 | 2761 |
NIFK,DDX24,KMT2E,PSPC1,TUFM,GTPBP4,UBE2Z,TBC1D13,EBNA1BP2,PPP3CB,SRSF5,WDR5,BRIX1,VPS25,RPL36,DGCR8,RTCB,CHMP7,HNRNPDL,FTSJ3,IFI16,VPS29,BYSL |
| 2.813e-04 | -8.18 | ERC1 (ELKS/RAB6-interacting/CAST family member 1) | protein interactions | 23085 | 68 | 23 | 17029 | 2761 |
MAPRE1,EWSR1,SNX2,PPP1R21,XIAP,CUL3,KIF23,RACGAP1,BRCA1,RAB6A,PCGF1,TWF2,ERC1,APP,RAD23A,CEP104,PCM1,WDR4,KBTBD7,SASS6,ATP6V0D1,DVL2,SRPK2 |
| 2.814e-04 | -8.18 | Aifm1 (apoptosis-inducing factor, mitochondrion-associated 1) | protein interactions | 26926 | 13 | 8 | 17029 | 2761 |
CHCHD3,IMMT,PHB2,CLU,VDAC1,CHCHD6,STOML2,NUDC |
| 2.814e-04 | -8.18 | MUTYH (mutY DNA glycosylase) | protein interactions | 4595 | 13 | 8 | 17029 | 2761 |
PCNA,AGTRAP,LRSAM1,HUWE1,MSH6,LMNA,RPA1,MSH2 |
| 2.814e-04 | -8.18 | IFIH1 (interferon induced with helicase C domain 1) | protein interactions | 64135 | 13 | 8 | 17029 | 2761 |
MAVS,IDE,PTEN,APP,USP21,PCBP2,PIAS2,NLRC5 |
| 2.814e-04 | -8.18 | TIPIN (TIMELESS interacting protein) | protein interactions | 54962 | 13 | 8 | 17029 | 2761 |
GINS1,TIMELESS,MCM2,APP,PRDX1,GINS4,SUPT16H,RPA1 |
| 2.814e-04 | -8.18 | GSTO2 (glutathione S-transferase omega 2) | protein interactions | 119391 | 13 | 8 | 17029 | 2761 |
FKBP1A,TXN,HINT1,WDR1,MUM1,TAGLN2,EDRF1,GPX4 |
| 2.814e-04 | -8.18 | RNU2-1 (RNA, U2 small nuclear 1) | protein interactions | 6066 | 13 | 8 | 17029 | 2761 |
GEMIN5,DDX20,GEMIN6,GEMIN4,SND1,STRAP,CDC5L,GEMIN7 |
| 2.815e-04 | -8.18 | TOOKER_GEMCITABINE_RESISTANCE_DN | MSigDB lists | TOOKER_GEMCITABINE_RESISTANCE_DN | 119 | 33 | 17377 | 2626 |
DHPS,RGS2,SPR,SLC20A1,TFRC,SSR1,PAPOLA,MBD4,FGFR3,APLP2,ADD3,CLIC4,DPYSL2,AHSA1,PDIA6,LPCAT1,SLC35A1,SRP72,MLEC,IDH3A,ACSL3,EZR,FKBP3,CYB5A,SH3GLB1,RHOB,VEZF1,ACYP1,CEBPG,LPCAT4,CLU,ATP6V1C1,XRCC4 |
| 2.817e-04 | -8.17 | YBX3 (Y-box binding protein 3) | protein interactions | 8531 | 107 | 32 | 17029 | 2761 |
PPAN,USP7,CYLD,CSRP1,SUZ12,RPL6,DHX9,CUL3,CUL1,MACF1,ABCF1,CAND1,DOT1L,CDK5,EIF4A3,E2F4,ZNF746,PELO,UBA5,RTCB,E2F1,H2AFX,COX5A,TARDBP,RRS1,CDK2,ARRB2,MAPK1,ATP6V0D1,ZC3HAV1,PCBP2,SRPK2 |
| 2.817e-04 | -8.17 | TNF (tumor necrosis factor) | protein interactions | 7124 | 107 | 32 | 17029 | 2761 |
CYLD,MTX3,B4GALT5,AGO2,RAC1,B4GALT1,PSMD9,LYN,BIRC2,LMNA,CDC42,BDH1,ACP2,ADAM17,CELSR2,TNFAIP3,NEK7,GUF1,SFXN5,MAP2K2,RHEB,FADD,FAS,OPTN,RAB18,SEC61A1,TAB2,SPATA2,KHSRP,ADAM9,NCLN,CLU |
| 2.817e-04 | -8.17 | IL13RA2 (interleukin 13 receptor subunit alpha 2) | protein interactions | 3598 | 107 | 32 | 17029 | 2761 |
FAM207A,B4GALT5,DNAAF5,B4GALT1,NOTCH2,ABHD14A,AHCTF1,NEK6,INTS7,ZNHIT6,BDH1,INTS12,KNTC1,SENP1,RBM15B,ZDHHC18,RB1CC1,ERF,NEK7,GUF1,SYMPK,CAND1,BRMS1,PTPRF,JAK1,VPS26C,PALB2,XRCC3,ST3GAL2,RNASEL,B4GALT3,ECPAS |
| 2.843e-04 | -8.17 | TRAF6 (TNF receptor associated factor 6) | protein interactions | 7189 | 310 | 74 | 17029 | 2761 |
USP7,TOMM20,CYLD,ATXN3,TRAF7,KMT2E,NF1,XIAP,RRAGC,USP39,IRF3,UBE2I,MAPK14,BECN1,BIRC2,APP,PARK7,USP5,PSMD1,IARS,MAST2,MAVS,BIRC3,MCL1,UBE2V1,VDAC1,ZFAND5,TOLLIP,USP21,PLEKHF2,DDX17,HSPA4,TAB2,UEVLD,PSMD3,H2AFX,TICAM1,FUS,ARRB2,SMURF1,TRAF5,PSMC1,UBE2D3,CYCS,WDR5,ASXL2,PSEN1,IRF4,PPP4R1,TANK,CTPS1,ZNF326,DCP1A,YBX1,MAP3K14,ZRANB1,STAT3,TRAFD1,NASP,TNFAIP3,ZMYND11,USP10,KRAS,KCNQ1,NFATC2IP,APPL1,TARS,IRF5,CSNK1G1,SNAP29,USP20,MAP3K5,DDB1,RNF114 |
| 2.846e-04 | -8.16 | SCHUHMACHER_MYC_TARGETS_UP | MSigDB lists | SCHUHMACHER_MYC_TARGETS_UP | 77 | 24 | 17377 | 2626 |
SRM,TMEM97,UCK2,LDHA,EBNA1BP2,CYCS,DCUN1D4,SLC20A1,ODC1,TFRC,PNO1,AKAP1,EXOSC7,IARS,TBL3,GRSF1,PRPS2,SLC16A1,AHCY,RRS1,GPD1L,MRPL3,LRP8,GCSH |
| 2.846e-04 | -8.16 | REACTOME_MITOTIC_G2_G2_M_PHASES | MSigDB lists | REACTOME_MITOTIC_G2_G2_M_PHASES | 77 | 24 | 17377 | 2626 |
PLK1,FGFR1OP,MAPRE1,DYNLL1,DCTN2,E2F3,TUBGCP5,PKMYT1,CCNB1,PRKACA,HAUS2,TUBGCP2,PCM1,CCNA2,CENPJ,E2F1,SSNA1,CDC25B,CEP63,CDK2,CCNB2,TUBB,CSNK1D,DCTN1 |
| 2.846e-04 | -8.16 | COPI-coated vesicle | cellular component | GO:0030137 | 24 | 11 | 18223 | 2701 |
TMED7,COPA,TMED10,SCYL1,COPE,PACS1,TMED3,COPG2,COPB2,TMED2,KDELR1 |
| 2.850e-04 | -8.16 | GO_ENDOSOMAL_PART | MSigDB lists | GO_ENDOSOMAL_PART | 403 | 87 | 17377 | 2626 |
ANKRD27,RAB14,SNX27,CHMP2A,GNPNAT1,RAB11B,RAC1,VTI1A,RRAGC,BECN1,RUFY1,APP,STAM,CD320,ATP6V0B,RAB21,RAB8A,SHC1,MTMR4,WDR44,RAB35,CLCN6,ZFYVE27,AP2B1,MARCH2,TMEM9,TMBIM1,SNX8,SNX25,CLCN3,ATG9A,RAB7A,ATP6V0A1,CHMP2B,AP4E1,RAB5B,RAB22A,PLEKHF2,CHMP4A,TAB2,RPS27A,TICAM1,ATP6V0C,CHMP4B,VPS4A,AP2S1,ATP6V0E1,STARD3NL,UBE2D3,GOLIM4,ANXA6,GGA1,HLA-E,RAB23,LAMTOR3,ACAP1,VPS45,GGA2,TMEM165,RAB11A,SCYL2,VPS25,TFRC,HLA-A,SPPL2A,CTSS,SNX18,ZNRF2,ATP6V0A2,PIKFYVE,ATP6V0D1,TPCN1,SNX2,RFFL,APPL1,SPPL2B,RHOB,PI4K2A,HLA-B,HGS,OSBPL11,APPL2,PML,EHD4,CHMP7,SNX14,VPS29 |
| 2.859e-04 | -8.16 | cell division site | cellular component | GO:0032153 | 83 | 25 | 18223 | 2701 |
MZT1,RHOA,SEPT9,RHOC,TUBGCP5,MYH9,SEPT8,RACGAP1,SEPT7,ANLN,MEN1,ICAM2,RAB11A,TUBGCP2,RHOB,RTKN,MASTL,TMEM250,PDXP,RAB21,SEPT1,CEP55,ITGB1,SEPT11,NDE1 |
| 2.861e-04 | -8.16 | LMO2 (LIM domain only 2) | protein interactions | 4005 | 153 | 42 | 17029 | 2761 |
KIF3B,MAPRE1,AGTRAP,CCZ1,DAZAP2,UBE2I,PHC2,RB1,MEX3C,SSBP3,CORO1A,STAT3,RPRD1B,HNRNPM,RLIM,CDC5L,CSTF1,RPRD1A,POLR2I,MAPRE2,ZFP64,POLR2L,POLR2G,DRAP1,LDB1,POLR2D,GORAB,ERBIN,POLR2A,AFDN,MBIP,SMAD2,POLR2J,GOLGA2,AXIN1,CORO1C,KBTBD7,STAT1,NUP62,MRFAP1L1,ROCK1,N4BP2L2 |
| 2.880e-04 | -8.15 | ribonucleoside monophosphate biosynthetic process | biological process | GO:0009156 | 109 | 31 | 17256 | 2622 |
AMPD2,TGFB1,GALK1,COX5B,UCK2,LDHA,ADSL,ATP6V0A1,UCK1,OGDH,ATP5F1B,ADPGK,PKM,ATP5MF,ATP5PF,STOML2,ADSS,GART,ATP5MC3,ATIC,PRPS2,UPRT,IMPDH1,ATP6V0A2,DHTKD1,GPI,ATP5F1A,CYC1,NIPSNAP2,PGAM1,PFKP |
| 2.895e-04 | -8.15 | ODONNELL_TFRC_TARGETS_DN | MSigDB lists | ODONNELL_TFRC_TARGETS_DN | 124 | 34 | 17377 | 2626 |
DEPDC1,FOXM1,CENPF,DBF4,MYNN,CCNB1,ITGB5,TFRC,FBXO5,CCNA2,MEX3C,KIF14,PRC1,GTSE1,TACC3,PLK1,MND1,ASPM,MYBL2,MKI67,RRM2,CKAP2L,CDC6,AURKB,ANLN,KIF11,SHCBP1,CHAF1A,RAD54B,BIRC5,CEP55,FAM83D,C4orf46,FKBP5 |
| 2.897e-04 | -8.15 | Generic Transcription Pathway | REACTOME pathways | R-HSA-212436 | 865 | 180 | 10287 | 1696 |
RORB,CCNC,ZNF496,TXN,TSC2,NOP2,CSNK2A1,CCNB1,UBE2I,MAPK14,FANCI,ZNF696,CDK5,PCNA,ZNF200,NOC2L,TCEA1,CARM1,MLST8,PLK3,ZNF559,AKT2,EHMT1,ELOA,AURKB,BRCA1,RFC2,RHEB,SMAD2,CHD3,RPS27A,ZNF689,E2F4,PRDX5,COX5A,STK11,ZNF268,CHEK2,TFDP2,ZNF45,ZNF75A,HDAC2,SSRP1,ZNF564,ZNF720,UBE2D3,COX5B,KRBA1,POLR2K,PRKAA1,LAMTOR3,NDUFA4,COX4I1,CDK13,CYCS,NOTCH2,ZNF79,CNOT11,JMY,CNOT3,TIGAR,MED8,MED10,ZNF746,MSH2,MAML1,ZNF189,POLR2I,MTA2,PIP4K2C,MYBL2,ZNF761,FAS,RXRB,TSC1,ZNF777,POLR2J,COX7A2L,LAMTOR4,MED15,ZFP90,YWHAZ,CNOT6,GPI,YY1,RBBP4,CDK2,NRBP1,CDKN2A,USP7,PRKAB1,TP53RK,PMS2,RMI2,TPX2,ZNF416,RRAGC,ZNF267,MEAF6,ZNF75D,MDM2,ZNF420,ZNF473,CCNA2,ZNF302,BRPF3,ZKSCAN1,PIN1,CDKN1B,ZNF226,TP53BP2,ATF2,ZNF770,CDK12,ZNF583,RFC3,POLR2L,POLR2G,ZNF500,BTG2,POLR2D,MBD3,TRIM28,SUPT16H,TAF2,PPP2CA,ZNF282,ZNF317,ZNF700,RBL1,HIPK2,ZNF436,NCOA1,SMAD4,RAD51D,CTDP1,ZNF786,NCOR2,ZNF445,CASP6,AGO2,BLM,RMI1,PIP4K2A,ZNF92,GTF2F1,CCNK,RPA2,PTEN,CENPJ,KMT5A,BRD7,CITED2,ZNF710,CNOT6L,GTF2H2,NCOA2,PDPK1,KAT2A,ZNF202,TOP3A,RFFL,MEN1,POLR2A,PRDX1,RPA1,CNOT9,ZNF180,ATAD2,BIRC5,TFDP1,PML,LRPPRC,COX8A,E2F1,TMEM219,TAF12,RBPJ,TAF6,YWHAH |
| 2.902e-04 | -8.15 | IVANOVA_HEMATOPOIESIS_MATURE_CELL | MSigDB lists | IVANOVA_HEMATOPOIESIS_MATURE_CELL | 262 | 61 | 17377 | 2626 |
OTUD5,USP7,CMAS,NAT9,GOLIM4,ADD1,CAST,PIGQ,CDCA3,C5orf30,AGFG1,RAB6A,SLC25A44,XPO7,MAP1LC3B,PITHD1,RMI1,MXD1,PRPF18,SLC25A37,UBLCP1,ATG4A,C1GALT1,CCNA2,CCP110,C4orf3,ARL6IP1,SRI,PRC1,GPATCH1,TCEA1,MARCH2,RNF19A,LPCAT1,ANKRD9,TMX1,MOSPD1,GPX4,NUDT4,ATP6V0A1,HTATIP2,RFFL,HERPUD2,HAGH,STK17B,PICALM,BRMS1,RAD51C,SERTAD2,MTHFD2,RAB24,GRIPAP1,DCK,USP32,PPP3R1,RBMS1,SLC16A1,FAM126A,TFDP2,SLC22A23,E2F2 |
| 2.902e-04 | -8.15 | PASQUALUCCI_LYMPHOMA_BY_GC_STAGE_UP | MSigDB lists | PASQUALUCCI_LYMPHOMA_BY_GC_STAGE_UP | 262 | 61 | 17377 | 2626 |
HIVEP3,MAGED1,GPR89A,UCK2,PAWR,NCKAP1,DUSP22,ITGB5,SSR1,IRF4,RPN1,IL6ST,LPIN2,RRBP1,TPST1,ANXA5,FNIP2,SLC38A10,TOP1MT,LMAN1,CITED2,CLTB,PDIA6,PPA1,KDELR1,ABCC1,LARS,RHOBTB3,ELL2,TSPAN31,NUDT4,SELPLG,BTG2,OXR1,MAN1B1,SSR2,GORASP2,EAF2,MCFD2,EDEM2,RHOB,EVC2,AMZ2,DERL1,PON2,SEC61A1,SURF4,TTC13,RBM47,STT3A,TMED10,CERS6,TULP3,NFIL3,SEL1L,ATP6V0C,CHID1,ABCA1,SLC25A39,GPR89B,SLC25A33 |
| 2.916e-04 | -8.14 | LRRC47 (leucine rich repeat containing 47) | protein interactions | 57470 | 44 | 17 | 17029 | 2761 |
EPRS,FGFR1OP,EXOSC7,TNFAIP3,PBK,ZNF746,BABAM1,USP42,USP32,PSMA1,EXOSC9,NFATC2,MAN2B1,EIF2A,COPS6,CD81,PNO1 |
| 2.916e-04 | -8.14 | CPT1A (carnitine palmitoyltransferase 1A) | protein interactions | 1374 | 44 | 17 | 17029 | 2761 |
NDUFV1,SNRNP200,NDUFS1,RHOA,NDUFA2,HUWE1,ERLIN1,RAB7A,KBTBD7,NDUFA4,BCL2,TOMM40,ATP6V1C1,CLN3,PCBP1,LYN,SDHA |
| 2.916e-04 | -8.14 | MRPL55 (mitochondrial ribosomal protein L55) | protein interactions | 128308 | 44 | 17 | 17029 | 2761 |
PLK1,MRPL9,MRPL42,MRPL39,MRPL12,ILF3,FLOT1,TOMM40,MRPL50,MRPL40,MRPL48,HNRNPDL,MRPL13,MRPL3,HNRNPM,MRPL32,CBX4 |
| 2.916e-04 | -8.14 | CDK12 (cyclin dependent kinase 12) | protein interactions | 51755 | 44 | 17 | 17029 | 2761 |
EWSR1,MAP4K4,ELOA,RNPS1,CDK13,BCLAF1,PCGF1,POLR2A,SRSF1,SUPT16H,CCNK,PIN1,RPS14,PRPF4,RRS1,CDK12,SRPK2 |
| 2.916e-04 | -8.14 | ATG101 (autophagy related 101) | protein interactions | 60673 | 44 | 17 | 17029 | 2761 |
LARS,COPA,RB1CC1,PRKDC,PCGF1,FOXO3,TARS,RPA1,ATG4A,PA2G4,UBA5,HADHB,LRPPRC,ATG13,CDC37,SSRP1,ALDH9A1 |
| 2.916e-04 | -8.14 | DUSP12 (dual specificity phosphatase 12) | protein interactions | 11266 | 44 | 17 | 17029 | 2761 |
EIF5A,USO1,NCK1,MBLAC2,PARK7,APP,HDDC2,DUSP3,ARF5,NDUFA11,EIF2D,VPS4A,MBD6,EIF5,MAPK1,HRAS,DCTN1 |
| 2.916e-04 | -8.14 | SLC39A9 (solute carrier family 39 member 9) | protein interactions | 55334 | 44 | 17 | 17029 | 2761 |
MTX3,NEK7,B4GALT5,TBRG4,PXMP2,MTX1,CDC23,XPO7,SFXN5,PDXDC1,GOLM1,BDH1,CANT1,APOOL,NR2F2,OSTC,ECPAS |
| 2.919e-04 | -8.14 | PPP6R2 (protein phosphatase 6 regulatory subunit 2) | protein interactions | 9701 | 64 | 22 | 17029 | 2761 |
PLK1,GORASP1,ASPM,PRKDC,ACSL3,SLC26A6,ZNF574,ATXN1,USP10,DCLRE1C,AP1B1,APP,ANKRD28,PFDN5,SH3GLB2,PPP6C,RUVBL2,PPP6R3,MOB1A,PPP6R1,MYO5A,NUDC |
| 2.928e-04 | -8.14 | GSE360_CTRL_VS_L_DONOVANI_MAC_UP | MSigDB lists | GSE360_CTRL_VS_L_DONOVANI_MAC_UP | 189 | 47 | 17377 | 2626 |
NCOR2,MPHOSPH8,CHERP,DAP,EIF3D,TMX4,AGPAT1,PPP3CB,AP1B1,UBE2I,SHC1,ARF5,GRSF1,TXLNA,AFF1,GNAI2,FAM3A,ZNF189,CYFIP1,POLR2L,TSTA3,PPT1,PARP4,KCNQ1,USP22,ESYT1,SLC25A5,PSMB9,ARMC8,FADD,MYO1F,SDHB,PAF1,NUCB1,AHNAK,POLR2J,TBL3,STK38,PPM1G,PIAS2,COX5A,PDXK,ARRB2,USF2,PDCD11,OAZ1,DDB1 |
| 2.928e-04 | -8.14 | GSE28737_BCL6_HET_VS_BCL6_KO_MARGINAL_ZONE_BCELL_DN | MSigDB lists | GSE28737_BCL6_HET_VS_BCL6_KO_MARGINAL_ZONE_BCELL_DN | 189 | 47 | 17377 | 2626 |
BCL2L12,PKP4,GXYLT1,GLUD1,PXMP2,FAM8A1,LRRC14,SMC3,NEK6,NVL,DNAAF2,ATP13A3,YBX1,DDX31,GEMIN4,MRPL21,NUP85,FTSJ3,CAMK2G,PREB,B3GALT6,KAT7,HELB,SCFD2,NLN,TBRG4,ATP6V0A1,UBE2V1,PITPNB,PRPSAP1,TARS,USP36,NCDN,ABHD5,AKAP1,ANKRD10,SPATA2,DHX16,CHCHD1,TOMM6,TFDP1,MEGF9,ACAT1,MLYCD,SMPD4,PDXK,PTDSS1 |
| 2.928e-04 | -8.14 | GSE5589_LPS_VS_LPS_AND_IL10_STIM_IL6_KO_MACROPHAGE_45MIN_DN | MSigDB lists | GSE5589_LPS_VS_LPS_AND_IL10_STIM_IL6_KO_MACROPHAGE_45MIN_DN | 189 | 47 | 17377 | 2626 |
MIF,ZNF207,NOP2,HLA-E,DBF4,TKT,CHIC2,TMEM165,HDDC2,DTL,ERH,ADD3,EIF4A3,NUP107,AHCY,TAP2,ACSL5,NOL12,BRD4,NXT1,FAM49B,IDH3A,SELPLG,ARHGDIB,CDCA2,KRAS,NFATC2IP,PKMYT1,KRTCAP2,OGFR,SHCBP1,LUC7L,ECH1,MAT2A,CLNS1A,SLCO4A1,DAP3,PPP2R5A,TATDN2,PTAR1,LY75,RUVBL2,SASS6,CCNB2,ESPL1,ANXA11,RNF114 |
| 2.928e-04 | -8.14 | GSE1925_CTRL_VS_IFNG_PRIMED_MACROPHAGE_DN | MSigDB lists | GSE1925_CTRL_VS_IFNG_PRIMED_MACROPHAGE_DN | 189 | 47 | 17377 | 2626 |
SRM,GCLM,DNAJC2,AGTRAP,POLR2K,XIAP,KIF23,USP39,MEF2A,SNN,CDK11B,ABHD14A,CD320,GART,MCM5,BANF1,PTPN11,BRI3,SUCLG2,YBX1,TMEM14C,RPL22L1,NUP85,PPAN,METTL1,RPL35,SEPT9,MIOS,RNASEH2C,ILF3,GTPBP4,CRNKL1,WDHD1,CDC6,TOMM40,KRTCAP2,RHOB,DPYSL3,GEMIN5,ALG3,SLC19A1,AP1S1,GAS2,RBBP4,YY1,BRWD3,SMNDC1 |
| 2.928e-04 | -8.14 | GSE1925_CTRL_VS_3H_IFNG_STIM_MACROPHAGE_UP | MSigDB lists | GSE1925_CTRL_VS_3H_IFNG_STIM_MACROPHAGE_UP | 189 | 47 | 17377 | 2626 |
SRM,IER2,NCOR2,DNAJC2,DNMT3A,TSC2,AGPAT3,SEC16A,HDDC2,PNO1,PABPC4,CD320,PAPOLA,IRF4,GART,MECR,RPN2,YBX1,POLR1B,AQR,CNN2,SLC35C2,AHCYL1,RPL22L1,TERF2,PPAN,METTL1,MIOS,GUK1,LAP3,PRKDC,ITM2A,SOX4,VKORC1,ODC1,DPYSL3,GEMIN5,SLC19A1,STAT6,GLG1,RPLP1,LONP2,SNX14,BYSL,GCSH,IPO4,DDB1 |
| 2.928e-04 | -8.14 | GSE17721_CTRL_VS_CPG_6H_BMDC_UP | MSigDB lists | GSE17721_CTRL_VS_CPG_6H_BMDC_UP | 189 | 47 | 17377 | 2626 |
TOMM20,GOLIM4,MANBA,GADD45G,FAM76A,ATG2B,LANCL1,HCFC1R1,SLC12A9,PRKACA,MIEN1,PARK7,EBP,TMEM179B,SMC3,GATC,BDH1,CORO1A,PHKG2,PDLIM2,GPX4,ELOVL5,ZNF524,PPP3CA,CYTH1,ERMP1,PTPN18,BAZ2A,ERLIN1,KIAA0930,ZNF574,POLR3GL,ARHGDIB,GLO1,EIF3H,CLNS1A,TFEB,ANKRD10,MRPL2,ACOX1,STK38,PIAS2,BAZ1B,GAS2,YWHAH,MYL12B,PTOV1 |
| 2.928e-04 | -8.14 | GSE17721_CTRL_VS_PAM3CSK4_8H_BMDC_UP | MSigDB lists | GSE17721_CTRL_VS_PAM3CSK4_8H_BMDC_UP | 189 | 47 | 17377 | 2626 |
NCOR2,NSMCE4A,C19orf53,MANBA,CENPF,HABP4,TKT,TIA1,CMTM6,HMG20A,XPR1,CAPN2,RAP1A,PCNA,KLF16,ATG3,BDH1,RPN2,CORO1A,TMEM14C,EIF5A,PTPN18,FAM49B,LAP3,NQO2,OXR1,MAP4K4,RPL6,CCDC34,CLNS1A,ANKRD10,GNAS,MKNK1,TPD52L2,OSBPL11,GALNT2,CHCHD1,LUC7L3,SOCS4,RPLP1,MPV17,ACAT1,PDXK,NCOA1,NDUFS5,RUFY3,CDK2 |
| 2.932e-04 | -8.13 | Cdc5l (cell division cycle 5-like (S. pombe)) | protein interactions | 71702 | 16 | 9 | 17029 | 2761 |
SNRNP200,AQR,CTNNBL1,XAB2,EFTUD2,PPIE,CRNKL1,CDC5L,PRPF19 |
| 2.932e-04 | -8.13 | SMTNL2 (smoothelin like 2) | protein interactions | 342527 | 16 | 9 | 17029 | 2761 |
CCNA2,SNAP29,NLN,CUL1,YWHAZ,MCM2,CDK2,YWHAH,APP |
| 2.932e-04 | -8.13 | OGFR (opioid growth factor receptor) | protein interactions | 11054 | 16 | 9 | 17029 | 2761 |
TERF2IP,USP7,MAGED2,TRMT6,LAGE3,FKBP5,BRCA1,TERF1,CDC37 |
| 2.932e-04 | -8.13 | HHV8GK18_gp78 (ORF69) | protein interactions | 4961444 | 16 | 9 | 17029 | 2761 |
MAT2B,DUT,PTPN11,ADSL,FN3KRP,METTL9,MTPN,CARM1,GPX4 |
| 2.933e-04 | -8.13 | GNF2_MSH6 | MSigDB lists | GNF2_MSH6 | 31 | 13 | 17377 | 2626 |
HNRNPA2B1,CCT2,RFC3,MTHFD2,H2AFZ,MRPL42,IARS,PRKDC,LRPPRC,MRPS27,MSH2,ADSL,MSH6 |
| 2.933e-04 | -8.13 | GREENBAUM_E2A_TARGETS_UP | MSigDB lists | GREENBAUM_E2A_TARGETS_UP | 31 | 13 | 17377 | 2626 |
CDKN2C,EPRS,CCNA2,H2AFX,MKI67,RACGAP1,NUSAP1,KIF2C,ANLN,CCNB1,SLC12A2,CCNB2,KIF11 |
| 2.951e-04 | -8.13 | KENNY_CTNNB1_TARGETS_DN | MSigDB lists | KENNY_CTNNB1_TARGETS_DN | 51 | 18 | 17377 | 2626 |
USP7,PPP3CA,TIMP2,OLA1,NARF,TMEM165,ITGB5,SDHA,KIF5B,PLAA,TNFAIP8,IL6ST,DPYSL2,SEL1L,DDX5,MDH1,PPP6R3,TMX1 |
| 2.951e-04 | -8.13 | PARK_HSC_AND_MULTIPOTENT_PROGENITORS | MSigDB lists | PARK_HSC_AND_MULTIPOTENT_PROGENITORS | 51 | 18 | 17377 | 2626 |
BCCIP,KAT2A,CTCF,LY6E,MAPK14,CCT8,RPSA,VEZF1,SERF2,BIRC5,FIZ1,TTC3,TAGLN2,SRSF3,NAP1L4,H3F3A,SMARCE1,ATP6V0E1 |
| 2.971e-04 | -8.12 | GSE8921_3H_VS_24H_TLR1_2_STIM_MONOCYTE_UP | MSigDB lists | GSE8921_3H_VS_24H_TLR1_2_STIM_MONOCYTE_UP | 184 | 46 | 17377 | 2626 |
CCDC93,DNMT3A,ABCA3,ZNF445,REPS2,SCOC,B4GALT5,MECP2,CTCF,CSNK2A1,SIKE1,COX4I1,CHAC2,DUSP22,TMCC3,RPL11,RAP1A,ASAP2,CLIC4,IL6ST,EXOSC1,AP1M1,CNN2,PIKFYVE,CTDSP2,ACSL5,ENPP4,SLC16A7,MTMR6,ICAM2,VKORC1,GUF1,EIF3K,GNA12,MID1IP1,PRDX3,CHD3,SCAP,ZC3H7B,FAM126A,ST3GAL2,SLC22A23,TRAF5,PURA,ATMIN,S100PBP |
| 2.971e-04 | -8.12 | GSE3982_EOSINOPHIL_VS_MAC_DN | MSigDB lists | GSE3982_EOSINOPHIL_VS_MAC_DN | 184 | 46 | 17377 | 2626 |
SLC12A7,TCF12,CCNC,CMAS,LUZP1,NF1,CAST,KIF23,COX4I1,PMVK,GLRX3,RAB11A,DDRGK1,GSTK1,ATP2A2,UTP18,MBD2,BANF1,MRPL34,H2AFY,SUCLG2,CENPM,AHCYL1,DNMT1,MTX2,NIPSNAP1,ATP6V1G1,TIMP2,HARS,ASPM,ABCF2,DCTD,MAP4K3,TOMM40,CBFB,CLNS1A,RHEB,OPTN,RDH11,NSA2,MAP3K4,DAP3,LSM6,IARS2,PDXK,PDSS2 |
| 2.971e-04 | -8.12 | GSE17721_POLYIC_VS_CPG_4H_BMDC_UP | MSigDB lists | GSE17721_POLYIC_VS_CPG_4H_BMDC_UP | 184 | 46 | 17377 | 2626 |
MRPL39,CDT1,SMC6,STMN1,ANKIB1,BIRC2,FANCL,RB1,SMC3,IARS,PELO,ORAI1,MINPP1,TMEM8A,TMEM14C,NIPSNAP1,SRPK2,VOPP1,PSRC1,ERMP1,ETV3,DENND4C,HELB,RPL38,HTATIP2,UHRF1BP1,MEF2D,WBP1,PNPLA8,METTL22,ZDHHC3,RPSA,DHX57,RPA1,KIF2A,DNAJC10,MRPL2,KEAP1,ATP6V1D,SERF2,RBM25,VPS26B,PDXK,FAU,ANAPC4,CSNK1D |
| 2.971e-04 | -8.12 | GSE17721_4_VS_24H_CPG_BMDC_DN | MSigDB lists | GSE17721_4_VS_24H_CPG_BMDC_DN | 184 | 46 | 17377 | 2626 |
TRIM41,RECQL,MIF4GD,MUT,GMFG,WDTC1,SLC39A13,DNAJB1,HCFC1R1,KCMF1,COPG2,RNF103,DDRGK1,USP5,MOAP1,BDH1,RAD23B,TTC3,GTF2H2,ABCC5,ACSL5,ZNF524,CYFIP1,CREG1,FOPNL,RNPS1,OGDH,CDC23,EIF4G2,KDM3A,CYB5A,EPB41,HGS,GRIPAP1,MFAP1,TULP3,NFIL3,SLC25A19,ADAM9,SIL1,MRFAP1L1,ZNF830,IGBP1,PGAM1,CPEB2,ADNP2 |
| 2.971e-04 | -8.12 | GSE21670_TGFB_VS_TGFB_AND_IL6_TREATED_STAT3_KO_CD4_TCELL_UP | MSigDB lists | GSE21670_TGFB_VS_TGFB_AND_IL6_TREATED_STAT3_KO_CD4_TCELL_UP | 184 | 46 | 17377 | 2626 |
CTU2,TOMM20,KRBA1,CCM2,FLOT1,KLF13,CHCHD2,SIKE1,CREBL2,NHLRC3,DNAJB1,SPR,FAM8A1,CMTM6,DNAJB9,GNS,CEP104,LHX8,BCL2,TAGLN2,PIK3IP1,CITED2,GPD1L,PPAN,YTHDC1,PPP3CA,PIGT,GALC,NOL8,NSUN2,KRAS,ARHGEF12,MCFD2,PDE3B,MAK16,MATR3,MAT2A,SMAP2,PCM1,BRD2,APPL2,PRMT7,SPRYD4,PDLIM5,APOL2,PTOV1 |
| 2.971e-04 | -8.12 | GSE17721_CTRL_VS_CPG_8H_BMDC_UP | MSigDB lists | GSE17721_CTRL_VS_CPG_8H_BMDC_UP | 184 | 46 | 17377 | 2626 |
ANKH,RAC1,TM9SF3,ZFYVE21,ORC1,COMMD5,PIP4K2A,CCDC28A,TFRC,PABPC4,XPR1,EBP,CTNNBL1,STRBP,CDC25B,CORO1A,CNOT6L,TMEM14C,MED22,PDLIM2,HP1BP3,ADCY7,ELOVL5,RAB7A,NQO2,KIAA0930,TMEM216,RPL38,RPL6,SEPT8,NEU1,MRPL2,DHX16,HNRNPH3,LUC7L3,PRPS2,OAZ2,ACAT1,HMGB2,CCNB2,C11orf1,NAA60,SNX14,TSPAN5,MRPL3,MYL12B |
| 2.971e-04 | -8.12 | GSE3982_MAST_CELL_VS_CENT_MEMORY_CD4_TCELL_UP | MSigDB lists | GSE3982_MAST_CELL_VS_CENT_MEMORY_CD4_TCELL_UP | 184 | 46 | 17377 | 2626 |
ABCA3,TKT,ENSA,FLOT1,NDUFA4,USP48,LYN,NDUFS7,COPB2,CHKA,ZNF804A,GNS,DST,ATP2A2,NDUFB4,TNPO3,MARCH2,MRPL40,MOB1A,TALDO1,GPD1L,ATP6V0D1,SOCS5,ENPP4,TIMM8B,CYFIP1,DCAF6,MKLN1,POLR2L,GALC,NQO2,CRNKL1,USP22,VDAC1,SOX4,COMMD4,PICALM,MFAP1,CORO1C,SEL1L,COX8A,CEBPG,GPI,HEXA,MAPK1,ABCA1 |
| 2.971e-04 | -8.12 | GSE11924_TH2_VS_TH17_CD4_TCELL_DN | MSigDB lists | GSE11924_TH2_VS_TH17_CD4_TCELL_DN | 184 | 46 | 17377 | 2626 |
CYTIP,NSMCE4A,FAM53C,TRIM11,TCF3,OLA1,PMS2,FAM76A,DLGAP4,RAB23,KCTD17,SMC6,GTF3A,HAUS4,CRLF3,MRPL19,MBD4,CHKA,WWP2,TIMM23,TBC1D14,AKAP8,AKR1B1,OSTF1,ERI3,CNNM3,NSUN4,PACS2,CSNK1G2,CCT2,KAT2A,GLO1,CYFIP2,RAB5B,ODC1,PDE3B,EIF3K,KIF2A,APPL2,PML,PITPNA,ST3GAL2,ZMIZ1,RNF14,COIL,DDX42 |
| 2.971e-04 | -8.12 | GSE24671_CTRL_VS_SENDAI_VIRUS_INFECTED_MOUSE_SPLENOCYTES_DN | MSigDB lists | GSE24671_CTRL_VS_SENDAI_VIRUS_INFECTED_MOUSE_SPLENOCYTES_DN | 184 | 46 | 17377 | 2626 |
MIB2,UBL3,PIGQ,EPN1,ARGLU1,USP48,SEC16A,SNAPC4,TRIM65,PARK7,NDUFS7,NFATC3,NUP210,FUT8,EXOSC1,FBL,CNOT6L,F2R,TPCN1,SPSB3,KDM3B,ORAI2,PTPN18,GABPA,NSUN2,TAOK1,ZNF574,WDR82,ARHGDIB,PACS1,AZI2,STX16,SLTM,EPB41,NECAP2,UBTF,WAS,AHNAK,SEC23IP,RBM25,DHX16,CHD3,RPS14,OGT,RNF38,SNRNP70 |
| 2.972e-04 | -8.12 | Interactions of Rev with host cellular proteins | REACTOME pathways | R-HSA-177243 | 36 | 15 | 10287 | 1696 |
NDC1,NUP188,NUP210,RAE1,NUP107,NUP54,NUP62,NUP153,NUP155,RANGAP1,NUP85,NUP58,SEH1L,AAAS,NUP205 |
| 2.977e-04 | -8.12 | double-strand break repair | biological process | GO:0006302 | 178 | 45 | 17256 | 2622 |
RECQL,EYA1,BABAM1,CIB1,SMC6,BLM,MAD2L2,WDR48,RFWD3,RPA2,BABAM2,CYREN,KDM2A,MTA1,XRCC2,NABP2,NABP1,MSH2,SPIDR,PRPF19,TDP1,MND1,ERCC1,PRKDC,RAD51AP1,DCLRE1C,BRCA1,GINS4,RAD54B,XRCC5,RPA1,RAD51C,PAXX,PALB2,TONSL,NSMCE2,CDCA5,H2AFX,XRCC3,CHEK2,YY1,GEN1,XRCC4,RAD51D,POLQ |
| 2.978e-04 | -8.12 | DNA-dependent ATPase activity | molecular function | GO:0008094 | 85 | 26 | 17224 | 2647 |
RECQL,RFC3,HELB,CHTF18,CHD1L,DHX9,SMARCA4,TOP2B,PBRM1,BLM,RFC2,CHD1,RAD54B,XRCC5,RAD51C,RAD18,CHD3,XRCC2,MSH2,XRCC3,RUVBL2,RBBP4,GTF2H2,MSH6,RAD51D,POLQ |
| 2.979e-04 | -8.12 | cell activation involved in immune response | biological process | GO:0002263 | 609 | 124 | 17256 | 2622 |
RHOG,ADA2,KARS,RAB14,ADAM10,DYNLL1,RAC1,HEXB,NIT2,NHLRC3,GYG1,MAPK14,LYN,KCMF1,CMTM6,CPNE3,APP,PA2G4,RAP1A,PSMD1,AP1M1,BRI3,CORO1A,PLCL2,TMBIM1,GM2A,KCNAB2,ENPP4,CPNE1,ERCC1,CCT2,TIMP2,EXOSC6,NRAS,RAB7A,ARHGAP45,PPIE,CYSTM1,PSMB7,ATP6V0A1,RAB5B,TOLLIP,ALDH3B1,DSN1,AGPAT2,DDOST,SURF4,RAB24,STAT6,PSMD3,CAB39,CANT1,ATP6V0C,TICAM1,ROCK1,PDXK,LTA4H,MAPK1,CAPN1,TUBB,SVIP,MIF,DNAJC5,GMFG,MANBA,PDAP1,LAMTOR3,B4GALT1,ASAH1,CDK13,MAN2B1,NOTCH2,EIF2AK4,RAB6A,DOCK11,PSEN1,TMEM179B,GNS,CD59,IRF4,PSMD2,CTSS,ARPC5,HUWE1,MSH2,OSTF1,CNN2,MVP,STAT3,LPCAT1,MSH6,SPTAN1,CYFIP1,FTL,MLEC,RHOA,CREG1,MFNG,ITM2A,HEBP2,C1orf35,PKM,ARMC8,CCT8,NEU1,HSPA1B,PI4K2A,CAND1,XRCC5,CAT,RAB18,TSC1,ATP6V1D,MAGT1,GOLGA7,SNAP29,SNAP23,ACLY,PGRMC1,IMPDH1,CTSA,PSAP,GPI,PGAM1 |
| 2.988e-04 | -8.12 | SAFB (scaffold attachment factor B) | protein interactions | 6294 | 94 | 29 | 17029 | 2761 |
UNK,COX15,STAU1,EWSR1,MPHOSPH8,RB1CC1,TCF3,SF3B6,CUL3,SMU1,SREK1,CSNK2A1,USP39,CYCS,SEPT7,VDAC1,SAFB2,MAP1LC3B,CHD1,MATR3,POLR2A,ABHD16A,SURF4,CHD3,RBMX,ACAT1,ABCC1,SRPK2,CDC37 |
| 2.988e-04 | -8.12 | RALY (RALY heterogeneous nuclear ribonucleoprotein) | protein interactions | 22913 | 94 | 29 | 17029 | 2761 |
COX15,STAU1,ERLIN1,SUZ12,HNRNPUL2,RPL6,DHX9,RNPS1,RANGAP1,BRCA1,PCBP1,MATR3,PHF6,LMNA,RPA1,CAND1,RPA2,SYNCRIP,STRBP,HNRNPR,DGCR8,RBMX,TARDBP,SNRNP70,WDR62,NKAPD1,PABPC1,HNRNPM,CDC5L |
| 2.989e-04 | -8.12 | intracellular transport of virus | biological process | GO:0075733 | 55 | 19 | 17256 | 2622 |
NDC1,NUP188,RAE1,NUP54,NUP155,NMT2,NUP205,NUP210,KPNA1,KPNA4,RPS27A,NUP107,NUP62,KPNA2,NUP153,NUP58,NUP85,AAAS,SEH1L |
| 3.001e-04 | -8.11 | GFPT1 (glutamine--fructose-6-phosphate transaminase 1) | protein interactions | 2673 | 60 | 21 | 17029 | 2761 |
UNK,RBX1,DNAAF5,ATP5F1B,XPO7,MCM2,CCT8,TARS,PSMC4,PFDN5,PSMD2,IARS,PFDN4,SETD3,PSMD3,AHSA1,KHSRP,ACADM,NMD3,POC5,LDHB |
| 3.001e-04 | -8.11 | PRPF4B (pre-mRNA processing factor 4B) | protein interactions | 8899 | 60 | 21 | 17029 | 2761 |
SART1,NIFK,SNRNP200,SNRPB,RNPS1,KLF13,USP39,LUC7L,SRSF1,DDX23,SUPT16H,RPS14,RBM34,EFTUD2,ZRANB2,PRPF4,ARRB2,NKAPD1,LUC7L2,SRPK2,CDC5L |
| 3.001e-04 | -8.11 | CDC34 (cell division cycle 34) | protein interactions | 997 | 60 | 21 | 17029 | 2761 |
UBE2D3,CORO7,RBX1,GNPDA1,VHL,CUL3,MYBL2,CUL1,TRIM28,USP5,WWP2,RAD23A,CREM,HINT1,SIAH1,FBXO7,CDKN1B,FBXW2,ROCK1,MARCH2,FBXL3 |
| 3.009e-04 | -8.11 | GSE22886_NAIVE_BCELL_VS_NEUTROPHIL_UP | MSigDB lists | GSE22886_NAIVE_BCELL_VS_NEUTROPHIL_UP | 179 | 45 | 17377 | 2626 |
RPS15,CHD1L,RPL15,HMGN3,RPL11,IRF4,TIMELESS,TTC3,MDFIC,EBAG9,POU2AF1,EIF3L,RPL35,TSPYL4,TEX10,CYP20A1,RPL8,RPL38,RPL6,EZR,RPS24,GLO1,MCM2,RPL27A,DDX39A,ODC1,PDHX,APPL1,RBM38,AKAP1,RPL37,MAP3K4,TSC1,FBXO21,NAP1L1,PDLIM1,RPS27A,RPS14,LRPPRC,RPLP1,ACAT1,MDH1,TRAF5,CD81,NMD3 |
| 3.009e-04 | -8.11 | GSE44955_MCSF_VS_MCSF_AND_IL27_STIM_MACROPHAGE_DN | MSigDB lists | GSE44955_MCSF_VS_MCSF_AND_IL27_STIM_MACROPHAGE_DN | 179 | 45 | 17377 | 2626 |
NCOR2,CHMP2A,LYRM4,UBN1,EIF3D,STARD7,KCTD17,ETS1,GNB2,CFLAR,ABL2,CAPN2,VASP,SHC1,MEGF8,BANF1,TTC9C,MRPL34,GPD1L,SLC25A1,NAGPA,PPP1R9B,RPRD1A,KIAA0040,PRRC2A,RAB7A,SELPLG,LDHA,SCFD2,PLEC,LY6E,SHCBP1,STK17B,PON2,FAM110A,GOLGA8A,STAT6,CABIN1,FKBP5,EHD4,BRD9,CHID1,AP2S1,ZC3HC1,SNAPIN |
| 3.009e-04 | -8.11 | GSE20198_UNTREATED_VS_IL12_IL18_TREATED_ACT_CD4_TCELL_DN | MSigDB lists | GSE20198_UNTREATED_VS_IL12_IL18_TREATED_ACT_CD4_TCELL_DN | 179 | 45 | 17377 | 2626 |
MRPL42,THOC1,NF1,WDYHV1,MRPL39,SRSF6,STRN4,ENSA,USP39,NDUFS4,SEC11A,CDKN2C,SUB1,POP7,ARL6IP1,YIF1B,CITED2,NSUN4,TMEM160,SAP30,FYTTD1,JMJD4,TELO2,ELOVL5,NSDHL,UTP15,DCTD,DCUN1D5,NDUFA7,KRTCAP2,C9orf40,VKORC1,KLF6,MAK16,MAT2A,NSA2,RAD51C,SERF2,ORMDL2,CERS6,CCDC6,ERGIC3,PIAS2,DDX5,WDR76 |
| 3.014e-04 | -8.11 | DDX23 (DEAD-box helicase 23) | protein interactions | 9416 | 81 | 26 | 17029 | 2761 |
SART1,STAU1,SNRNP200,XAB2,SUZ12,PIP4K2C,RNPS1,CERK,USP39,PRPF3,BRCA1,TXNL4A,SF3A2,PIP4K2A,LMNA,RPA1,TERF2IP,RPA2,HNRNPR,EFTUD2,KIFAP3,PRPF4,SNRPG,TERF1,PURA,PRPF4B |
| 3.014e-04 | -8.11 | MRPS34 (mitochondrial ribosomal protein S34) | protein interactions | 65993 | 81 | 26 | 17029 | 2761 |
FAM92A,MRPS2,MRPS15,NOA1,USP42,RPL6,ZNF574,MRPS26,CUL3,MRPS10,ATP5MF,SLC25A5,MRPS14,CAND1,FAM192A,DDX56,DAP3,STRBP,GRSF1,ZNF746,MRPS27,TRMT10B,TARDBP,PREPL,ZNF770,PDF |
| 3.014e-04 | -8.11 | CATTTCA,MIR-203 | MSigDB lists | CATTTCA,MIR-203 | 273 | 63 | 17377 | 2626 |
TCF12,CCNC,PPP1R12A,ARID2,SESTD1,MECP2,PDAP1,C5orf30,YTHDF3,CUL1,NKRF,CSNK1A1,MYEF2,ABHD14A,DLG5,RAP1A,MEX3C,RALB,SOCS6,GPATCH1,AP2B1,JOSD1,COPS7B,TARDBP,SPTSSA,CITED2,SLC12A2,SRSF10,PRPF19,SLC39A9,TSHZ1,FOXK1,ELL2,MBLAC2,ZMYND11,KIAA0930,MAP4K3,ARID1A,STX16,NDRG3,API5,APPL1,SRSF1,C1orf122,KIF2A,PLAA,ETS2,OSBPL8,MAFK,PRPS2,ARNTL,RNF38,CAB39,FKBP5,ANP32E,ZRANB2,MBD6,SMAD1,ZMIZ1,GLCCI1,SMURF1,PDSS2,EGLN1 |
| 3.019e-04 | -8.11 | Taf15 (TATA-box binding protein associated factor 15) | protein interactions | 70439 | 48 | 18 | 17029 | 2761 |
FAM208B,DHX9,ILF3,SAFB2,SLTM,HNRNPA2B1,DGCR8,HNRNPR,RBMX,HNRNPH3,SAFB,ZNF326,COPS7B,RBM3,RBM12B,BTBD10,HNRNPDL,FAM208A |
| 3.019e-04 | -8.11 | NUP155 (nucleoporin 155) | protein interactions | 9631 | 48 | 18 | 17029 | 2761 |
UNK,STAU1,PTPN18,CUL3,TMEM216,BRCA1,ADRB2,UBE2I,LMNA,EVC2,ALDH3B1,KBTBD7,NUP107,NUP153,GLE1,DMWD,SEH1L,CDC5L |
| 3.041e-04 | -8.10 | prostate-hyperplasia | COSMIC cancer mutations | prostate-hyperplasia | 11 | 7 | 17385 | 2587 |
GNAS,FGFR3,RB1,KRAS,NRAS,SF3B1,HRAS |
| 3.042e-04 | -8.10 | GSE37416_CTRL_VS_6H_F_TULARENSIS_LVS_NEUTROPHIL_DN | MSigDB lists | GSE37416_CTRL_VS_6H_F_TULARENSIS_LVS_NEUTROPHIL_DN | 174 | 44 | 17377 | 2626 |
MIF,CTDP1,CYLD,DAP,RBM8A,ALKBH5,MYNN,ORC1,RLF,POFUT1,MFSD10,TFRC,PHC2,PSMA6,C4orf3,BRPF3,BRI3,PIK3IP1,CYC1,RNF19A,ZNF770,SAP30,GUK1,ANKRD37,ATG9A,LDHA,NARF,AMDHD2,VDAC1,KDM3A,ABCF1,TRIM28,ANKZF1,FNTA,DUSP3,MFAP1,SIAH2,PKD2,PDXK,RBPJ,GPI,PGAM1,NGLY1,PDCD2L |
| 3.051e-04 | -8.09 | PAFAH1B2 (platelet activating factor acetylhydrolase 1b catalytic subunit 2) | protein interactions | 5049 | 56 | 20 | 17029 | 2761 |
RHOA,TUFM,PSMG1,EIF4H,BZW2,ABHD14A,HNRNPA2B1,TPD52L2,IDE,SNUPN,WDR4,PPP1R12C,OGT,RTCB,PPP5C,TATDN1,CDK2,STAT3,TIMM50,LDHB |
| 3.051e-04 | -8.09 | ILVBL (ilvB acetolactate synthase like) | protein interactions | 10994 | 56 | 20 | 17029 | 2761 |
RAB14,VDAC2,CUL3,FLOT1,ATXN1,ADRB2,RAB1A,KIF11,PICALM,NCDN,SRSF1,SDHB,THADA,INTS1,INTS12,ACAT1,CYC1,PPP6R2,CLN3,PPP6R1 |
| 3.051e-04 | -8.09 | YAF2 (YY1 associated factor 2) | protein interactions | 10138 | 56 | 20 | 17029 | 2761 |
USP7,DCAF6,AGGF1,UBXN1,PCGF6,CSNK2A1,WDR5,PCGF1,CAND1,CBX3,FBRS,PAF1,MDM2,TRIM26,TFDP1,FBXO7,CTR9,YY1,HDAC2,RYBP |
| 3.051e-04 | -8.09 | INTS6 (integrator complex subunit 6) | protein interactions | 26512 | 56 | 20 | 17029 | 2761 |
INTS2,CTDP1,POLR2G,POLR2L,DDX24,INTS13,POLR2D,POLR2A,RPA1,PPP2CA,RPA2,POLR2J,INTS7,INTS1,NABP1,NABP2,INTS12,CTDSP2,C7orf26,CDC5L |
| 3.051e-04 | -8.09 | PGD (phosphogluconate dehydrogenase) | protein interactions | 5226 | 56 | 20 | 17029 | 2761 |
RPS6KA1,SUMO2,RBM8A,LDHA,EZR,LSM8,BRCA1,EIF4H,CDC73,ISG15,CTSL,C12orf10,AHSA1,HMGB2,TCEA1,TALDO1,CDK2,TERF1,ALDH9A1,LDHB |
| 3.051e-04 | -8.09 | EIF4H (eukaryotic translation initiation factor 4H) | protein interactions | 7458 | 56 | 20 | 17029 | 2761 |
UNK,MRPL9,EWSR1,PSPC1,RPS6KA1,EIF4G2,KDM3A,EIF3A,MAT2B,GNAS,GART,SYNCRIP,AHSA1,TRA2B,FUS,SRSF3,EIF5,ECPAS,HNRNPDL,LDHB |
| 3.059e-04 | -8.09 | structural constituent of nuclear pore | molecular function | GO:0017056 | 27 | 12 | 17224 | 2647 |
NDC1,NUP188,NUP107,NUP54,NUP62,NUP155,NUP153,NUTF2,NUP58,NUP85,NUP205,TMEM33 |
| 3.061e-04 | -8.09 | PSIP1 (PC4 and SFRS1 interacting protein 1) | protein interactions | 11168 | 52 | 19 | 17029 | 2761 |
EWSR1,CAST,RPL6,RPS24,CSNK2A1,THRAP3,MEN1,SRSF1,RPA1,SUPT16H,RPA2,SUB1,EIF4A3,BANF1,MAPK6,TRA2B,RBPJ,RRS1,FTSJ3 |
| 3.061e-04 | -8.09 | NAA15 (N(alpha)-acetyltransferase 15, NatA auxiliary subunit) | protein interactions | 80155 | 52 | 19 | 17029 | 2761 |
CMAS,TRAFD1,INTS13,DHX9,KRAS,BRCA1,MATR3,XRCC5,HNRNPR,PSMD3,UBA5,ZNF746,NAA50,STAT1,NAA20,FBL,ARRB2,POC5,DCTN1 |
| 3.061e-04 | -8.09 | INTS5 (integrator complex subunit 5) | protein interactions | 80789 | 52 | 19 | 17029 | 2761 |
INTS2,SKA3,POLR2G,POLR2L,INTS13,POLR2D,TGOLN2,GLMP,POLR2A,PPP2CA,HLA-B,POLR2J,INTS7,INTS1,NABP1,NABP2,INTS12,CLU,C7orf26 |
| 3.061e-04 | -8.09 | SUCLA2 (succinate-CoA ligase ADP-forming beta subunit) | protein interactions | 8803 | 52 | 19 | 17029 | 2761 |
MKLN1,SUCLG1,AGTRAP,HPDL,IDH3A,MRPL12,MCCC1,RRM1,NADK2,NIT2,NFATC2,AGFG1,SDHA,RBM4,SDHB,ARL6IP1,ACADM,LONP2,ZNF146 |
| 3.061e-04 | -8.09 | SMC6 (structural maintenance of chromosomes 6) | protein interactions | 79677 | 52 | 19 | 17029 | 2761 |
NSMCE4A,MUM1,HEXB,MKI67,SMC6,IFT27,TMEM165,MAK16,SCARB2,HSPB11,RAD18,PRDX3,DGCR8,HPS5,NSMCE2,TTC3,BTF3,SLF1,SLF2 |
| 3.061e-04 | -8.09 | TOX4 (TOX high mobility group box family member 4) | protein interactions | 9878 | 52 | 19 | 17029 | 2761 |
SRSF11,FTL,SF3B1,PPP1R21,STRN4,ATXN1,WDR82,STK17B,LMNA,SF3B2,HSPA4,HUWE1,CTR9,GEMIN6,CREB1,TERF1,HIPK3,FGFR1OP2,TERF2 |
| 3.061e-04 | -8.09 | ZC3H11A (zinc finger CCCH-type containing 11A) | protein interactions | 9877 | 52 | 19 | 17029 | 2761 |
PPIF,USP7,PPIB,IER2,SARNP,THOC1,FOXM1,GSPT2,BCLAF1,BRCA1,NDUFA7,SUGP1,NDUFA2,KBTBD7,PQBP1,RBMS1,XRCC3,TARDBP,NKAPD1 |
| 3.074e-04 | -8.09 | central_nervous_system-brain-glioma-ependymoma_Grade_II | COSMIC cancer mutations | central_nervous_system-brain-glioma-ependymoma_Grade_II | 14 | 8 | 17385 | 2587 |
TSC1,RB1,NRAS,PTEN,KRAS,H3F3A,HRAS,CDKN2A |
| 3.074e-04 | -8.09 | pituitary-adenoma-non_functioning | COSMIC cancer mutations | pituitary-adenoma-non_functioning | 14 | 8 | 17385 | 2587 |
GNAS,CDKN2C,RB1,NRAS,KRAS,MEN1,HRAS,CDKN2A |
| 3.074e-04 | -8.09 | ACTH | COSMIC cancer mutations | ACTH | 14 | 8 | 17385 | 2587 |
GNAS,CDKN2C,RB1,NRAS,KRAS,MEN1,HRAS,CDKN2A |
| 3.074e-04 | -8.09 | pituitary-adenoma-ACTH | COSMIC cancer mutations | pituitary-adenoma-ACTH | 14 | 8 | 17385 | 2587 |
GNAS,CDKN2C,RB1,NRAS,KRAS,MEN1,HRAS,CDKN2A |
| 3.075e-04 | -8.09 | TGAATGT,MIR-181A,MIR-181B,MIR-181C,MIR-181D | MSigDB lists | TGAATGT,MIR-181A,MIR-181B,MIR-181C,MIR-181D | 454 | 96 | 17377 | 2626 |
ZNF207,HECA,IVNS1ABP,AGPAT1,YTHDF3,TM9SF3,AGFG1,SNN,DAZAP2,LCLAT1,MEAF6,SLC25A37,ATP2A2,DPYSL2,JAZF1,ETV6,ADCY9,ANKRD13C,TARDBP,PLCL2,PDIA6,GPD1L,SENP1,ZNF800,MTPN,ARL5A,CCAR1,CARM1,CGGBP1,SRPK2,BAZ2A,LRBA,CUL3,ATXN1,DHX57,MAT2A,RBM47,BRWD1,GOLGA8A,SEL1L,OGT,MAPK1,CBX4,DYNC1LI2,SCOC,MECP2,ADO,C16orf87,B4GALT1,PAWR,ETS1,RLF,RAB11A,CDC73,FKBP1A,CCNK,MEX3C,ITGB8,KLHL5,MED8,INPP5A,SEC24C,SS18L1,AFF1,UBE3C,CREB1,LPCAT1,NCOA2,CAMK2G,CSNK1G3,PHF20L1,FOXK1,USP42,ILF3,CAMSAP1,RTF1,BCLAF1,MTMR12,CBFA2T2,KLF6,PICALM,NMT2,PI4K2A,DERL1,KPNA1,OSBPL8,CSNK1G1,FAM3C,PPP3R1,TBPL1,ZDHHC7,HMGB2,PSAP,NAA20,PDLIM5,S100PBP |
| 3.075e-04 | -8.09 | ATP1B3 (ATPase Na+/K+ transporting subunit beta 3) | protein interactions | 483 | 103 | 31 | 17029 | 2761 |
RPL35,ABCA3,NDUFS1,EWSR1,RPLP2,TM9SF4,TMX4,VDAC2,PTP4A3,BRCA1,GALNT7,ADRB2,OGDH,TOMM40,RAB1A,VDAC1,ITGB5,REEP5,RPS9,ATP1A1,NDUFA2,RPL17,QARS,IMPAD1,ACAT1,UPF2,NDUFS5,CYC1,SCARB1,RTN3,ATP6V0D1 |
| 3.080e-04 | -8.09 | GO_REGULATION_OF_ORGANELLE_ASSEMBLY | MSigDB lists | GO_REGULATION_OF_ORGANELLE_ASSEMBLY | 144 | 38 | 17377 | 2626 |
TBC1D12,CHMP2A,FEZ2,PDCD6IP,CYLD,PHF23,KCTD17,TBC1D13,UBQLN2,STAM,PIP4K2A,RALB,TBC1D22A,ATG3,CENPJ,TBC1D14,CNOT6L,PIKFYVE,LRSAM1,RNF5,PLK1,SEPT9,RAB7A,PIP4K2C,EZR,BRCA1,SEPT7,CHMP2B,SH3GLB1,MTMR3,TBC1D17,CHMP4A,ODF2,STX18,MAP4,ATXN2L,CNOT6,CHMP4B |
| 3.088e-04 | -8.08 | GSE6269_FLU_VS_STAPH_AUREUS_INF_PBMC_UP | MSigDB lists | GSE6269_FLU_VS_STAPH_AUREUS_INF_PBMC_UP | 164 | 42 | 17377 | 2626 |
MPHOSPH8,MUM1,TCF3,RBM8A,DNAJC24,SLC25A12,SMC6,CDK13,PAWR,EZH1,GGA2,SYNRG,RPA2,GSDMB,MTMR4,AHSA1,PIGG,DVL2,PTPRK,MAPRE2,KAT2A,PBXIP1,ZNF500,ZMYND11,DCAF8,WDR82,DIDO1,ESYT1,LRRC1,POLG2,NMT2,CYB5A,BRWD1,JAK1,C1orf109,FAM3C,TRIM32,SNRNP70,ZNF45,PDCD11,CSNK1D,ZBTB24 |
| 3.093e-04 | -8.08 | IPO5 (importin 5) | protein interactions | 3843 | 112 | 33 | 17029 | 2761 |
SCAMP3,SUMO2,HEXB,IRF3,RPL23A,MCTS1,RPN1,DDX56,TNFAIP8,HUWE1,ATIC,MRPL34,RPN2,NUP153,FBL,CDC5L,STAU1,CUL3,EZR,RANGAP1,BRCA1,CAND1,MTMR3,ATP1A1,PCM1,KPNA1,SEC61A1,NUP62,TERF1,CCDC59,HDAC2,FAF1,IPO4 |
| 3.093e-04 | -8.08 | negative regulation of autophagy | biological process | GO:0010507 | 77 | 24 | 17256 | 2622 |
UBQLN4,LARS,FEZ2,TSC2,KDM4A,PHF23,DAP,MCL1,SIRT2,EIF4G2,BECN1,USP36,TSC1,CHMP4A,TIGAR,GOLGA2,TAB2,TBC1D14,BCL2,CHMP4B,CTSA,SNRNP70,HTRA2,RNF5 |
| 3.095e-04 | -8.08 | KDM1A (lysine demethylase 1A) | protein interactions | 23028 | 321 | 76 | 17029 | 2761 |
CCDC93,IMMT,MAX,SUMO2,SNX15,CSNK2A1,IKBIP,UBE2I,RCOR3,MBD4,SF3B2,PHC2,OIP5,UCHL5,RABGAP1L,MTA1,SOCS6,DNMT1,TIMM50,ELOF1,CDC5L,NFATC2,BRCA1,CDC23,GSTCD,MBD3,TRIM28,ZMYM3,CDCA4,CHD3,CCDC14,GRIPAP1,ARNTL,SH3GLB2,ZNF436,ARRDC1,KLHDC4,PSMC1,HDAC2,INTS2,UNK,NDUFS1,PPP1R12A,TCF3,PMF1,CRLF3,PSMD9,HMG20A,KIF5B,RPA2,TEDC2,RB1,MBD2,UBE3C,STAT3,MCPH1,PHF20L1,RPRD1A,PRIM2,TACC1,MTA2,RCOR1,ATP5MF,TTC33,ARHGAP15,RPA1,TSC1,GOLGA2,L3MBTL3,CDCA5,E2F1,RBPJ,RBBP4,TERF1,ZBTB24,SMARCD1 |
| 3.097e-04 | -8.08 | BAH | pfam domains | PF01426 | 11 | 7 | 17054 | 2545 |
ORC1,ASH1L,PBRM1,TNRC18,MTA1,MTA2,DNMT1 |
| 3.097e-04 | -8.08 | zf-CXXC | pfam domains | PF02008 | 11 | 7 | 17054 | 2545 |
KMT2B,CXXC4,MBD1,KDM2A,FBXL19,DNMT1,CXXC1 |
| 3.100e-04 | -8.08 | GARCIA_TARGETS_OF_FLI1_AND_DAX1_DN | MSigDB lists | GARCIA_TARGETS_OF_FLI1_AND_DAX1_DN | 159 | 41 | 17377 | 2626 |
CCNC,MAPRE1,H2AFZ,MCM10,RRP15,TRMT6,UCK1,WDR5,C19orf48,TCF19,RMI1,HAUS2,DTL,STRBP,DUT,PPCDC,BRD7,CENPM,MRPL48,MRPL11,CDC37,NAGPA,TELO2,ARHGAP17,HPDL,MYBL2,RFFL,RRM2,CDC6,BICD2,AMDHD2,FANCE,TWISTNB,GEMIN5,ADSS,CHCHD3,INF2,CDCA5,WDR76,CDK2,E2F2 |
| 3.100e-04 | -8.08 | GO_REGULATION_OF_UBIQUITIN_PROTEIN_LIGASE_ACTIVITY | MSigDB lists | GO_REGULATION_OF_UBIQUITIN_PROTEIN_LIGASE_ACTIVITY | 17 | 9 | 17377 | 2626 |
PLK1,GOLGA2,PTEN,GORASP1,XRCC3,CCNB1,RAB1A,GEN1,FBXO5 |
| 3.100e-04 | -8.08 | GO_LYSOPHOSPHOLIPID_ACYLTRANSFERASE_ACTIVITY | MSigDB lists | GO_LYSOPHOSPHOLIPID_ACYLTRANSFERASE_ACTIVITY | 17 | 9 | 17377 | 2626 |
AGPAT2,LPCAT4,AGPAT1,MBOAT1,AGPAT3,LCLAT1,TAZ,LPCAT1,ABHD5 |
| 3.100e-04 | -8.08 | GO_SMN_SM_PROTEIN_COMPLEX | MSigDB lists | GO_SMN_SM_PROTEIN_COMPLEX | 17 | 9 | 17377 | 2626 |
GEMIN5,SNRPB,DDX20,GEMIN6,GEMIN4,SNRPG,SNRPD3,STRAP,GEMIN7 |
| 3.100e-04 | -8.08 | REACTOME_PHOSPHORYLATION_OF_THE_APC_C | MSigDB lists | REACTOME_PHOSPHORYLATION_OF_THE_APC_C | 17 | 9 | 17377 | 2626 |
PLK1,CDC16,CDC27,ANAPC2,ANAPC7,CCNB1,CDC23,UBE2C,ANAPC4 |
| 3.100e-04 | -8.08 | GO_U1_SNRNP | MSigDB lists | GO_U1_SNRNP | 17 | 9 | 17377 | 2626 |
LUC7L3,SNRPB,SNRPG,PRPF39,SNRNP70,SNRPD3,LUC7L,SNRPA,LUC7L2 |
| 3.103e-04 | -8.08 | GSE40274_CTRL_VS_XBP1_TRANSDUCED_ACTIVATED_CD4_TCELL_DN | MSigDB lists | GSE40274_CTRL_VS_XBP1_TRANSDUCED_ACTIVATED_CD4_TCELL_DN | 154 | 40 | 17377 | 2626 |
KARS,TOMM20,RPS2,ST13,B4GALT5,OLA1,HMGN3,SDF2L1,CHKA,LYAR,GART,EXOSC7,AHSA1,EFTUD2,MAST2,PDIA6,FTSJ3,RBM15B,PLK1,PLK3,GUK1,SCFD2,WDHD1,TMEM147,PRDX1,EIF3H,EIF3A,MASTL,SRSF1,UTP20,ADSS,IDE,TIMM13,KIF18B,TWSG1,TBL3,PPP5C,PGAM1,GPATCH4,ZC3HC1 |
| 3.104e-04 | -8.08 | LGR4 (leucine rich repeat containing G protein-coupled receptor 4) | protein interactions | 55366 | 216 | 55 | 17029 | 2761 |
IMMT,NOP2,SF3B1,DHX9,MYH9,ZNRF3,THRAP3,SRRT,TFRC,NUP205,RFWD3,RPN1,NUP210,IARS,ATP2A2,RRBP1,PIGG,GPATCH1,RPF2,UPF2,AQR,FTSJ3,SMC4,DCTN1,SNRNP200,PRRC2A,PRKDC,ILF3,ITM2A,SLC25A5,PDHX,MATR3,EIF3A,POLR2A,DDX17,GEMIN5,AFDN,EPRS,TBC1D17,ATP1A1,SURF4,RBM25,CHD3,SAFB,TBL3,MAP4,WDR4,LRPPRC,SLC16A1,KHSRP,ACTB,TCOF1,PDCD11,N4BP2L2,TUBB |
| 3.122e-04 | -8.07 | NAKAMURA_TUMOR_ZONE_PERIPHERAL_VS_CENTRAL_UP | MSigDB lists | NAKAMURA_TUMOR_ZONE_PERIPHERAL_VS_CENTRAL_UP | 268 | 62 | 17377 | 2626 |
HNRNPAB,MRPL42,NOP2,FAM129A,ABCC10,UROD,MYH9,RACGAP1,EBNA1BP2,POMP,CHAC2,NCAPG,ETS1,ITGB5,MRPL19,NDUFS7,ANKRD39,NPLOC4,SRXN1,CALM2,PSMD2,PSMD1,PSMA6,ATG3,MCM5,POP7,GEMIN6,CENPM,MRPL48,EIF5,N4BP2,RNF5,PTPRK,CCT2,ABHD2,TK1,AATF,TACC1,NET1,PBK,PSMA1,EZR,LRRC8A,RRM2,KRAS,NFATC2,MTX1,SOX4,SHCBP1,DERL1,RAD51C,INF2,IDE,SYNCRIP,BIRC5,CEP55,KPNA2,CCNB2,PSMC1,LRP8,ABCA1,GPATCH4 |
| 3.124e-04 | -8.07 | V$SP1_Q2_01 | MSigDB lists | V$SP1_Q2_01 | 231 | 55 | 17377 | 2626 |
TCF12,RHOG,DNMT3A,ADAM10,PHF23,GGA1,ZNF768,ZFP91,TM9SF3,KLF13,MXD4,HCFC1R1,DCUN1D4,CHKA,PTPN2,FBXO3,APLP2,KDM2A,ATP2A2,KLF16,SNX18,UTP18,FUT8,TIMELESS,CTR9,ANP32A,UPF2,CREB1,FBXL19,CGGBP1,CAMK2G,SP3,CLPTM1,POLR2I,OSBP2,SNX2,AKT2,LYRM1,LDB1,RTF1,CADM1,WDR81,ERC1,TRIM28,RAB2B,SH3BP5,CORO1C,OAZ2,ACLY,BCL7C,PITPNA,NR2F2,RTN3,FAF1,SMARCD1 |
| 3.124e-04 | -8.07 | ALFANO_MYC_TARGETS | MSigDB lists | ALFANO_MYC_TARGETS | 231 | 55 | 17377 | 2626 |
CYTIP,KARS,ABCA3,AGRN,GNPDA1,CDK2AP2,UCK2,FLOT1,EBNA1BP2,BLM,SLC20A1,TCF19,ITGB5,STMN1,CPNE3,CD59,TFAP4,FARSA,ADD3,ARPC5,PPP6C,ARL6IP1,TP53BP2,TTLL12,MVP,GNAI2,GPD1L,ABCC5,PPIF,TIMP2,CSRP1,AATF,KIAA0930,ABCF2,TUFM,MYBL2,PSMG1,MCL1,PLEC,TOMM40,LY6E,ASB13,RAB5B,GOSR1,PICALM,DDX17,GLOD4,AKAP1,PEX5,TATDN2,IMPDH1,SLC16A1,TCOF1,SMPD4,PDCD11 |
| 3.124e-04 | -8.07 | CHOI_ATL_STAGE_PREDICTOR | MSigDB lists | CHOI_ATL_STAGE_PREDICTOR | 35 | 14 | 17377 | 2626 |
SEC11A,FTL,NAP1L1,HSPA4,ST13,DUT,GMFB,RRAGC,MRFAP1L1,TARDBP,GORASP2,RBBP4,CMTM6,PRPF4B |
| 3.124e-04 | -8.07 | GO_POSITIVE_REGULATION_OF_VIRAL_TRANSCRIPTION | MSigDB lists | GO_POSITIVE_REGULATION_OF_VIRAL_TRANSCRIPTION | 35 | 14 | 17377 | 2626 |
TFAP4,CTDP1,POLR2I,POLR2G,POLR2L,POLR2J,POLR2K,ZNF639,POLR2D,SMARCA4,MDFIC,CHD1,POLR2A,GTF2F1 |
| 3.134e-04 | -8.07 | nucleotidyltransferase activity | molecular function | GO:0016779 | 137 | 37 | 17224 | 2647 |
POLA2,CMAS,KARS,CDS2,UGP2,POLR2K,NANS,POLR3K,TUT4,NEXMIF,PAPOLA,FLAD1,CD3EAP,RPAP1,PCYT2,POLR1B,PTGES3,ZNRD1,TERF2,POLR2I,PRIM2,POLR2L,POLR2G,CGAS,POLK,POLR2D,POLR3GL,POLG2,POLR2A,TWISTNB,PRIM1,POLE,POLR2J,UAP1,CRCP,TERF1,POLQ |
| 3.142e-04 | -8.07 | GO_ANTIGEN_PROCESSING_AND_PRESENTATION | MSigDB lists | GO_ANTIGEN_PROCESSING_AND_PRESENTATION | 205 | 50 | 17377 | 2626 |
KIF3B,HLA-E,DYNLL1,DCTN2,TAP1,KLC1,KIF23,RACGAP1,KIF2C,RAB6A,ARF1,AP1B1,PSMD9,ITGB5,BCAP31,HLA-A,PSMD2,PSMD1,CTSS,PSMA6,RAB35,SEC24C,RAB4A,AP1M1,DNM2,AP2B1,KIFAP3,KIF22,TAP2,DCTN1,PSMA8,RAB7A,KIF15,PSMB7,PSMA1,KIF11,RAB5B,PSMB9,PSMB3,PSMC4,KIF2A,SEC31A,HLA-B,KIF18A,PSMD8,PSMD3,AP1S1,PSMC1,AP2S1,DYNC1LI2 |
| 3.142e-04 | -8.07 | AP2M1 (adaptor related protein complex 2 subunit mu 1) | protein interactions | 1173 | 221 | 56 | 17029 | 2761 |
NCOR2,DDX47,CORO7,REPS2,GPBP1L1,KIAA0232,MYH9,EPN1,TGOLN2,AP1B1,CDK11B,REPS1,ANKRD28,HNRNPA2B1,UTP25,SHC1,MTMR4,ZNF746,MEA1,GTSE1,AP2B1,CRY2,CLTB,DVL2,NAGPA,STAU1,RAB7A,PRKDC,PRKAR1B,CUL3,RPL38,CAPZA2,KCNQ1,ANLN,SLC25A5,PICALM,MARK2,HSPA1B,NECAP2,PEX5,RPS27A,CORO1C,MAP4,MYO18A,KBTBD7,ATXN2L,AP1S1,STK11,ACTB,RUVBL2,PPP6R2,ARRB2,FAM208A,AP2S1,TUBB,NUMB |
| 3.159e-04 | -8.06 | Inhibition of replication initiation of damaged DNA by RB1/E2F1 | REACTOME pathways | R-HSA-113501 | 13 | 8 | 10287 | 1696 |
POLA2,PPP2CA,RB1,TFDP2,PRIM2,TFDP1,PRIM1,E2F1 |
| 3.159e-04 | -8.06 | Znf_CXXC | interpro domains | IPR002857 | 11 | 7 | 18492 | 2768 |
KMT2B,MBD1,CXXC4,KDM2A,FBXL19,DNMT1,CXXC1 |
| 3.159e-04 | -8.06 | BAH_dom | interpro domains | IPR001025 | 11 | 7 | 18492 | 2768 |
ORC1,ASH1L,PBRM1,TNRC18,MTA1,MTA2,DNMT1 |
| 3.159e-04 | -8.06 | RWD-domain | interpro domains | IPR006575 | 11 | 7 | 18492 | 2768 |
EIF2AK4,RWDD1,RNF14,WDR59,RNF25,DHX57,RWDD4 |
| 3.159e-04 | -8.06 | Methyl_CpG_DNA-bd | interpro domains | IPR001739 | 11 | 7 | 18492 | 2768 |
MBD1,MBD6,MBD3,BAZ2A,MECP2,MBD2,MBD4 |
| 3.159e-04 | -8.06 | DNA-bd_dom_sf | interpro domains | IPR016177 | 11 | 7 | 18492 | 2768 |
MBD1,MBD6,MBD3,BAZ2A,MECP2,MBD2,MBD4 |
| 3.172e-04 | -8.06 | KEGG_CHRONIC_MYELOID_LEUKEMIA | MSigDB lists | KEGG_CHRONIC_MYELOID_LEUKEMIA | 73 | 23 | 17377 | 2626 |
TGFB1,NRAS,AKT2,RAF1,E2F3,KRAS,BCL2L1,MAP2K2,MAPK3,CRKL,RB1,MDM2,SHC1,PIK3R2,E2F1,PTPN11,CDKN1B,MAPK1,E2F2,SMAD4,HRAS,HDAC2,CDKN2A |
| 3.178e-04 | -8.05 | REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_XBP1S | MSigDB lists | REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_XBP1S | 43 | 16 | 17377 | 2626 |
YIF1A,SEC31A,SHC1,ADD1,TATDN2,CXXC1,SYVN1,PDIA6,CTDSP2,SERP1,ATP6V0D1,DNAJB9,LMNA,PREB,SSR1,DCTN1 |
| 3.178e-04 | -8.05 | KEGG_AMINO_SUGAR_AND_NUCLEOTIDE_SUGAR_METABOLISM | MSigDB lists | KEGG_AMINO_SUGAR_AND_NUCLEOTIDE_SUGAR_METABOLISM | 43 | 16 | 17377 | 2626 |
GALK1,CMAS,GNPNAT1,UGP2,TSTA3,GNPDA1,GNE,HEXB,GALK2,NANS,AMDHD2,UAP1,GPI,CYB5R1,NANP,HEXA |
| 3.178e-04 | -8.05 | NAKAMURA_CANCER_MICROENVIRONMENT_DN | MSigDB lists | NAKAMURA_CANCER_MICROENVIRONMENT_DN | 43 | 16 | 17377 | 2626 |
PSMG1,USP39,CDCA2,CDC6,KIF2C,TARS,FANCI,SPAG5,TNS3,PA2G4,KLHL5,IARS,SYNCRIP,IMPAD1,FAM83D,CCNB2 |
| 3.178e-04 | -8.05 | LEE_AGING_MUSCLE_UP | MSigDB lists | LEE_AGING_MUSCLE_UP | 43 | 16 | 17377 | 2626 |
POU3F2,MECP2,STARD7,ARHGDIB,RAB1A,RHOB,RAB21,HINT1,CDC42,ARF5,AP3S2,DDX5,ZFP90,HEXA,USP53,DCTN1 |
| 3.182e-04 | -8.05 | Ercc6l (excision repair cross-complementing rodent repair deficiency complementation group 6 like) | protein interactions | 236930 | 33 | 14 | 17029 | 2761 |
NOP9,PLK1,UTP20,DDX28,SCAMP3,NDUFB4,TIMM23,RPL17,PHF14,RMI2,TOP3A,NAP1L4,BLM,RMI1 |
| 3.182e-04 | -8.05 | TMEM177 (transmembrane protein 177) | protein interactions | 80775 | 33 | 14 | 17029 | 2761 |
MRPL50,MRPL9,SYNCRIP,HPDL,RRM1,SEPT11,NADK2,NDUFA4,KRAS,MRPL16,NIT2,SRSF3,MRPL11,MRPL19 |
| 3.182e-04 | -8.05 | MALSU1 (mitochondrial assembly of ribosomal large subunit 1) | protein interactions | 115416 | 33 | 14 | 17029 | 2761 |
MRPL50,DDX28,MRPL42,RBM42,MRPL39,RBMX,MRPL12,MRPL43,CIRBP,DCTD,CHMP2B,HNRNPDL,MRM3,ZC3H3 |
| 3.185e-04 | -8.05 | myelin sheath | cellular component | GO:0043209 | 157 | 40 | 18223 | 2701 |
MIF,NDUFV2,PDCD6IP,NDUFS1,IMMT,MDH2,TKT,SLC25A12,SIRT2,ATP5F1B,ATP6V1B2,SDHA,GNB2,NAPG,RAP1A,GOT2,PTEN,AKR1B1,BCL2,LDHB,CCT2,IDH3A,WDR1,VDAC2,TUFM,EZR,PKM,SLC25A5,PRDX1,ATP1A1,NSF,PRDX3,RPS27A,EXOC4,ITGB1,COX5A,MDH1,PITPNA,ATP5F1A,PGAM1 |
| 3.197e-04 | -8.05 | GO_NUCLEAR_REPLICATION_FORK | MSigDB lists | GO_NUCLEAR_REPLICATION_FORK | 39 | 15 | 17377 | 2626 |
POLA2,RPA2,PCNA,MCM10,POLE,TONSL,HELB,XPA,BAZ1B,TOP1MT,PURA,GINS4,RPA1,PRPF19,CDC5L |
| 3.200e-04 | -8.05 | hyperplasia | COSMIC cancer mutations | hyperplasia | 52 | 18 | 17385 | 2587 |
NRAS,SF3B1,KRAS,MEN1,CDC73,MAP2K2,GNAS,RB1,FGFR3,PTEN,AXIN1,IL6ST,MSH2,PTPN11,STAT3,HRAS,SMAD4,CDKN2A |
| 3.209e-04 | -8.04 | ZNF324B (zinc finger protein 324B) | protein interactions | 388569 | 77 | 25 | 17029 | 2761 |
RPS15,ZNF445,AATF,ZNF316,YTHDC2,UTP15,ZNF107,TOPORS,ZNF121,TRIM28,DHX57,ZNF92,DAP3,LTBP4,DGCR8,RPS27A,ZNF689,ZNF746,YBX1,AHDC1,MRPL13,ZBTB11,NSUN4,DDX52,ZBTB24 |
| 3.209e-04 | -8.04 | TCEA1 (transcription elongation factor A1) | protein interactions | 6917 | 77 | 25 | 17029 | 2761 |
BCCIP,CTDP1,SNRNP200,POLR2G,LDHA,KIF23,RTF1,NFATC2IP,EAF2,MCM2,APP,CDC73,POLR2A,GTF2F1,IWS1,SF3B2,PAF1,DUS3L,KLHL20,RBM25,SLC38A7,MCM5,INTS1,CTR9,DDX5 |
| 3.209e-04 | -8.04 | LAMTOR3 (late endosomal/lysosomal adaptor, MAPK and MTOR activator 3) | protein interactions | 8649 | 77 | 25 | 17029 | 2761 |
RAB14,DDX28,COX15,MRPL39,MRPL43,RRAGC,TOMM40,PEF1,MAP2K2,PICALM,RHOB,MAPK3,RAB21,NDUFA2,NDUFB4,RALB,MBD2,QARS,MPV17,NDUFB9,LPCAT1,MAPK1,NUP58,MRM3,CDKN2A |
| 3.209e-04 | -8.04 | SARNP (SAP domain containing ribonucleoprotein) | protein interactions | 84324 | 77 | 25 | 17029 | 2761 |
FYTTD1,EWSR1,THOC1,VHL,TPX2,RNPS1,UBE4B,SEPT7,UBE2I,DDX39A,SCYL2,SH3GLB1,CDK5,SUB1,EIF4A3,LIMK1,PPIG,KBTBD7,NABP2,RBMS1,FUS,CHTOP,CDK2,WDR45B,PPP2R2D |
| 3.221e-04 | -8.04 | regulation of microtubule-based process | biological process | GO:0032886 | 199 | 49 | 17256 | 2622 |
CHMP2A,SKA3,PDCD6IP,MAPRE1,CYLD,RAE1,MECP2,POC1A,CDK2AP2,RAC1,PRKAA1,CIB1,TPX2,RGS2,STMN1,SPAG5,SMC3,CENPJ,ARHGEF2,CDKN1B,MCPH1,TACC3,DCTN1,PLK1,PSRC1,RHOA,KAT2A,TCTEX1D2,TAOK1,MEMO1,CAMSAP1,BICD2,BRCA1,CCNF,CHMP2B,RHOT1,KIF11,BORA,MACF1,HSPA1B,KIF18A,MID1IP1,NUP62,CHMP4B,XRCC3,KLHL42,CFAP20,GEN1,IGBP1 |
| 3.223e-04 | -8.04 | YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_11 | MSigDB lists | YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_11 | 96 | 28 | 17377 | 2626 |
SRM,METTL1,PPAN,USP39,KRAS,CYCS,BMS1,SLC35B1,BECN1,MAK16,SRRT,TARS,TFRC,PNO1,EPB41,NUDT19,RPN1,PA2G4,EPRS,PELO,KPNA2,SRSF3,RRS1,PDIA6,LRRC59,STRAP,FTSJ3,BYSL |
| 3.227e-04 | -8.04 | CTTTGTA,MIR-524 | MSigDB lists | CTTTGTA,MIR-524 | 410 | 88 | 17377 | 2626 |
WASF2,PRKAB1,TMEM184B,ADD1,ADAM10,RAC1,C5orf30,PLAGL2,GLUD1,PPP1R16B,MXD1,CREM,CSDE1,HNRNPA2B1,DLG5,RAB21,STRBP,CDC42,WDR44,JAZF1,HADHB,METTL9,SPTSSA,EIF5,LRRC59,MTPN,SEH1L,SRSF10,SP3,LRBA,HNRNPF,LRP5,PPFIA3,GALNT7,PRKRA,KRTCAP2,SOX4,TANC1,SERP1,EPB41,IWS1,PEX5,TAB2,NCOA1,PPP5C,SMAD4,ABCA1,UBE2D3,PRPF38B,SESTD1,SRSF6,ZFP91,GSPT2,FAM76A,SLC25A12,NKRF,RAB11A,PTPN2,FKBP1A,KLHL5,PPP1R8,LTN1,TSHZ1,PPP3CA,PHF20L1,NUDT4,MIER1,RTF1,ARHGEF12,MAP4K3,SRSF5,ARMC8,API5,APPL1,BSDC1,ZFR,CBX3,KPNA4,SERF2,ETS2,L3MBTL3,APPL2,TAF12,YY1,ZMIZ1,BTBD10,NR2F2,CPEB2 |
| 3.231e-04 | -8.04 | CSNK1D (casein kinase 1 delta) | protein interactions | 1453 | 90 | 28 | 17029 | 2761 |
TDP1,KCTD17,KLC1,NFATC2,BRCA1,RAB1A,CSNK1A1,APP,CDK5,DAP3,MDM2,SMAD2,PCM1,AXIN1,PML,PPP6C,FAM83D,MICU2,YWHAZ,CRY2,RP2,DVL1,SMURF1,SMAD4,BYSL,GEMIN7,VPS13B,SNAPIN |
| 3.235e-04 | -8.04 | LGALS3 (galectin 3) | protein interactions | 3958 | 192 | 50 | 17029 | 2761 |
SLC12A7,CYLD,TXN,RAB11B,MCCC1,RRAGC,CSNK2A1,SLC4A2,SPR,CSNK1A1,APP,TMEM179B,CYHR1,PPIG,ADCY9,ATP13A3,PTPN11,SS18L1,AHCY,SLC26A2,GEMIN4,MCPH1,SLC12A2,PCBP2,PRPF19,CDC5L,PTPRK,ENPP4,CLCN3,RPL35,ACP2,ATG9A,RAB7A,EMB,BRCA1,CADM1,SLC17A5,SLC25A5,PDHX,CLNS1A,MAPK3,NAP1L1,ATP1A1,DDOST,GOLGA2,DBI,ITGB1,IGBP1,MYL12B,CAPN1 |
| 3.259e-04 | -8.03 | GDP binding | molecular function | GO:0019003 | 59 | 20 | 17224 | 2647 |
RAB14,RHOA,RAB11B,RAB7A,RRAGC,KRAS,RAB5B,RAB22A,RHOB,RHEB,MIEF1,RAB8A,RAB21,RAB18,RALB,RAB35,PRPS2,RAB4A,SUCLG2,HRAS |
| 3.263e-04 | -8.03 | protein methyltransferase activity | molecular function | GO:0008276 | 90 | 27 | 17224 | 2647 |
HEMK1,ASH1L,KMT2E,SUZ12,CXXC1,EHMT1,ARMT1,NSD3,WDR82,EZH1,PRMT2,MEN1,KMT2C,METTL22,ICMT,WDR5,DOT1L,IRF4,SUV39H2,KMT5C,KMT5A,SETD3,CAMKMT,KMT2B,PRMT7,FBL,CARM1 |
| 3.271e-04 | -8.03 | GSE33424_CD161_HIGH_VS_NEG_CD8_TCELL_UP | MSigDB lists | GSE33424_CD161_HIGH_VS_NEG_CD8_TCELL_UP | 195 | 48 | 17377 | 2626 |
UBE2D3,SLC30A9,UBL3,RAB14,MIF4GD,ADAM10,PPP1R15B,SRGN,TOR3A,EIF2AK4,GGA2,OAT,CRLF3,ETS1,LYN,KTN1,DNAJB9,UBLCP1,MBD4,SLC25A36,GNS,STRBP,INPP5A,SLC44A1,AKAP8,MDFIC,MTPN,ARL5A,MYO5A,POU2AF1,CYFIP1,BIRC3,FAM49B,SNX2,EID1,MCL1,EIF4G2,LUC7L,IRF5,HSPA4,TXNDC16,RAB24,SAFB,QRSL1,PSAP,HEXA,ABCA1,SMNDC1 |
| 3.271e-04 | -8.03 | GSE29949_MICROGLIA_VS_DC_BRAIN_UP | MSigDB lists | GSE29949_MICROGLIA_VS_DC_BRAIN_UP | 195 | 48 | 17377 | 2626 |
IER2,CTDP1,PPP1R2,GNPDA1,GADD45G,AGPAT1,DHX8,ZNF267,GIT2,ANKRD26,TNFAIP8,HUWE1,GOT2,FAM89B,MDFIC,MARCH2,MINPP1,STRAP,GPX4,TGFB1,ELL2,CIC,JTB,DNAJC9,SREK1,PRPF3,SOX4,FXR1,CBFB,DDX39A,PRDX1,EIF3A,ABHD5,UBTF,YIF1A,MAP3K4,PLD3,TPD52L2,MKNK1,LTBP4,UAP1,OSBPL8,TATDN2,MAP4,LRPPRC,ADAM9,PDXK,H3F3A |
| 3.289e-04 | -8.02 | p38 MAPK Signaling Pathway | WikiPathways | WP400 | 34 | 14 | 5312 | 837 |
MKNK1,HMGN1,MAX,CDC42,SHC1,RAC1,STAT1,MEF2D,CREB1,ELK1,MAP3K5,MAPK14,ATF2,HRAS |
| 3.293e-04 | -8.02 | positive regulation of cellular component organization | biological process | GO:0051130 | 1166 | 219 | 17256 | 2622 |
PDCD6IP,NPHP4,PLXNC1,ADD1,AGRN,KMT2E,PLXNA1,SIRT2,CCNB1,MIEN1,BECN1,MAPK14,PARK7,EEF2K,CDK5,ABL2,ZNF804A,DLG5,RAP1A,CDC42,DNM2,ZFYVE27,AP2B1,FNIP2,DNMT1,CARMIL1,MLST8,CDC37,BAK1,ERCC1,SEPT9,RBX1,NCK1,AKT2,LRP5,AURKB,BRCA1,ANLN,OPTN,STOML2,DPYSL3,MAP3K4,PAF1,WAS,LIMK1,MYO18A,OGT,ADAM9,STK11,PIEZO1,CLU,DVL1,ROCK1,TFDP2,ARRB2,SLF1,POT1,PSMC1,C2CD5,UBE2D3,MAPRE1,PHB2,RHOC,PRKAA1,CIB1,KCTD17,NCKAP1,RGS2,DOCK11,PSEN1,PARN,APOPT1,SPAG5,JMY,CFLAR,LYAR,DDX56,SUB1,PDXP,RB1,VASP,CCP110,ARPC5,MEGF8,FBXO7,XPA,CTR9,TENM3,BCL2,LRSAM1,EIF5A,CYFIP1,ATP5IF1,WDR1,GBA,PIP4K2C,BCLAF1,RTF1,ADRB2,SEPT7,CBFA2T2,ARPC1A,SF3A2,CCT8,PSMC4,CAND1,XRCC5,TSC1,SCARB2,GOLGA4,CDCA5,PPP3R1,ARAP1,NUP62,YWHAZ,CNOT6,RUVBL2,RUFY3,WASF2,RHOG,ANKRD27,POC1A,DYNLL1,CHD1L,ACTR3,RAC1,LYN,TWF2,APP,MIEF1,MOAP1,HNRNPA2B1,CRKL,RRN3,RAB21,RALB,AKAP8,CDKN1B,TP53BP2,LMAN1,CHTOP,SPIDR,HTRA2,DVL2,CFL1,DCTN1,PPIF,CCT2,PSRC1,PPT1,KAT7,CUL3,WBP2,WIPF1,NUSAP1,NFATC2,TRIM28,USP36,IDE,SURF4,CORO1C,NSMCE2,CBLN2,SMURF1,MAPK1,SMAD4,LRP8,ATMIN,MECP2,CDT1,FLOT1,TRAK1,CBLL1,RAB11A,SCYL2,PIP4K2A,KIF5B,RPA2,HUWE1,CENPJ,NABP2,H2AFY,BRD7,ATG13,SS18L1,CNOT6L,CREB1,GTF2H2,TGFB1,PPP3CA,RHOA,KAT2A,NEK7,NET1,MIER1,ANAPC2,LLPH,MACF1,MARK2,PICALM,SH3GLB1,MAPK3,MFN2,RPA1,HSPA1B,PLAA,STX18,MAPK6,TFDP1,E2F1,PML,YWHAH,UBE2C,HRAS,ESPL1,SLF2,TERF1,DDB1,FAF1 |
| 3.300e-04 | -8.02 | regulation of intracellular pH | biological process | GO:0051453 | 91 | 27 | 17256 | 2622 |
CLCN3,PPT1,TM9SF4,RAB7A,GPR89A,SLC26A6,ATP6V0A1,SLC4A2,ATP5F1B,ATP6V1B2,TMEM165,ATP6V0B,ATP6V1D,CLIC4,ATP6V0A2,BCL2,ATP6V0C,SLC26A2,ATP6V1C1,CLN3,CLN6,ATP6V0D1,ATP6V0E1,GPR89B,SNAPIN,ATP6V1G1,CHP1 |
| 3.301e-04 | -8.02 | Bladder cancer | KEGG pathways | hsa05219 | 41 | 16 | 7161 | 1149 |
NRAS,RAF1,E2F3,KRAS,MAP2K2,DAPK3,MAPK3,RB1,FGFR3,MDM2,DAPK1,E2F1,E2F2,MAPK1,HRAS,CDKN2A |
| 3.301e-04 | -8.02 | Bladder cancer | KEGG pathways | ko05219 | 41 | 16 | 7161 | 1149 |
NRAS,RAF1,E2F3,KRAS,MAP2K2,DAPK3,MAPK3,RB1,FGFR3,MDM2,DAPK1,E2F1,E2F2,MAPK1,HRAS,CDKN2A |
| 3.308e-04 | -8.01 | organelle disassembly | biological process | GO:1903008 | 64 | 21 | 17256 | 2622 |
PLK3,ATG9A,RB1CC1,KLC1,ATG2B,MAP1LC3B,BECN1,MARK2,GFM2,MCTS1,ATG4A,KIF5B,GOLGA2,ATG3,FBXO7,PELO,EIF2D,CISD2,ATG13,WIPI2,WDR45B |
| 3.314e-04 | -8.01 | CENPS (centromere protein S) | protein interactions | 378708 | 26 | 12 | 17029 | 2761 |
FANCL,RPA2,FAAP100,RMI2,TOP3A,CENPT,BLM,FANCE,RMI1,APP,CENPU,RPA1 |
| 3.314e-04 | -8.01 | Anapc16 (anaphase promoting complex subunit 16) | protein interactions | 52717 | 26 | 12 | 17029 | 2761 |
CLIC4,CDC16,RAD18,CDC27,RABIF,ANAPC2,ANAPC7,CDC23,CCNB1,ANAPC4,SF3B2,FBXO5 |
| 3.331e-04 | -8.01 | GSE17721_LPS_VS_PAM3CSK4_12H_BMDC_UP | MSigDB lists | GSE17721_LPS_VS_PAM3CSK4_12H_BMDC_UP | 190 | 47 | 17377 | 2626 |
POU3F2,DNAJC2,KARS,TXN,TRIP12,DHPS,RHOC,TPX2,TBC1D13,THRAP3,IL21R,ANKIB1,WDR48,CFLAR,HOMER1,CLIC4,SH3BP1,PIK3R2,FUT8,TNPO2,ARHGEF2,AP2B1,TAGLN2,CNN2,NSUN4,SEH1L,MORC3,SAP30,CYTH1,CSRP1,LAP3,PGS1,RAB3IP,IL12RB1,ICAM2,ASB13,KLF6,SCARB2,CDC27,UAP1,MAPK6,BBX,DTD1,EHD4,PDLIM5,CPEB2,NRBP1 |
| 3.331e-04 | -8.01 | GSE5542_UNTREATED_VS_IFNG_TREATED_EPITHELIAL_CELLS_6H_DN | MSigDB lists | GSE5542_UNTREATED_VS_IFNG_TREATED_EPITHELIAL_CELLS_6H_DN | 190 | 47 | 17377 | 2626 |
LZTR1,ANKRD13D,DCAF15,NF1,B4GALT5,FAM129A,SRGN,TMX4,MYH9,MXD4,NCKAP1,GGA2,SLC25A43,PPP1R16B,LYN,REEP5,PIP4K2A,CDC73,XPR1,CFLAR,MAN1A1,DLG5,ADCY9,PPP4R1,ANXA5,OSTF1,RNF19A,MYBL1,CNNM3,MYO5A,TGFB1,SNRNP200,ERMP1,TACC1,DENND1B,CUL3,ATXN1,MAP2K2,MYO1F,GNAS,CACNB1,UEVLD,ARNTL,DTD1,MAP3K5,GLCCI1,YWHAH |
| 3.331e-04 | -8.01 | GSE3982_BASOPHIL_VS_EFF_MEMORY_CD4_TCELL_UP | MSigDB lists | GSE3982_BASOPHIL_VS_EFF_MEMORY_CD4_TCELL_UP | 190 | 47 | 17377 | 2626 |
WASF2,NDUFV2,H2AFZ,CKLF,REPS2,MED13L,SMC6,NDUFA4,ATP6V1B2,MAPK14,GIT2,MXD1,CFLAR,PRNP,CTNNBL1,SRSF4,RAB4A,BRD7,INTS12,UPF2,OSTF1,NFU1,CEP63,PIKFYVE,SMC4,VPS13B,SOCS5,TIMM8B,RHOA,EID1,CREG1,CRNKL1,ZDHHC3,ABHD5,PSMC4,HLA-B,VEZF1,PLAA,JAK1,WDR11,DBI,SIAH2,CAB39,ZDHHC7,CHPT1,CCDC59,ANXA11 |
| 3.331e-04 | -8.01 | GSE33425_CD161_HIGH_VS_INT_CD8_TCELL_UP | MSigDB lists | GSE33425_CD161_HIGH_VS_INT_CD8_TCELL_UP | 190 | 47 | 17377 | 2626 |
ZNF207,UBL3,RAB14,ASH1L,MIF4GD,SCOC,KLC1,IRF3,EIF2AK4,SND1,GGA2,OAT,LYN,RUFY1,CHD1,DNAJB9,GNS,NUDT19,RB1,CTSS,RAB35,TBC1D14,TPST1,SUCLG2,TIPARP,MTPN,DRAM2,POU2AF1,CYFIP1,SNX2,GABPA,ELL2,CIC,PPP1R21,ILF3,WBP2,MCL1,DIDO1,CBFA2T2,VKORC1,POLR2A,IRF5,HHEX,TXNDC16,SAFB,ADAM9,PSAP |
| 3.331e-04 | -8.01 | GSE7831_UNSTIM_VS_CPG_STIM_PDC_1H_UP | MSigDB lists | GSE7831_UNSTIM_VS_CPG_STIM_PDC_1H_UP | 190 | 47 | 17377 | 2626 |
HIVEP3,TCF12,DEPDC1,RPS6KA1,CDK2AP2,MYH9,THRAP3,SEC16A,IFT27,MIEN1,IL21R,PIP4K2A,PRPF18,EBP,ABHD16A,C1GALT1,WDR44,NT5DC1,DAD1,RNF26,SPTSSA,F2R,CFL1,TMX1,ADCY7,ORAI2,ABHD2,MLEC,RBM42,MAP4K4,CUL3,SLBP,ARHGDIB,MTMR12,IL12RB1,CYFIP2,NECAP2,NUCB1,SLCO4A1,CDCA4,RBMS1,ACBD4,USP20,HMGB2,CLN3,EYA2,ESYT2 |
| 3.349e-04 | -8.00 | leukocyte activation involved in immune response | biological process | GO:0002366 | 605 | 123 | 17256 | 2622 |
RHOG,ADA2,KARS,RAB14,ADAM10,DYNLL1,RAC1,HEXB,NIT2,NHLRC3,GYG1,MAPK14,LYN,KCMF1,CMTM6,CPNE3,PA2G4,RAP1A,PSMD1,AP1M1,BRI3,CORO1A,PLCL2,TMBIM1,GM2A,KCNAB2,ENPP4,CPNE1,ERCC1,CCT2,TIMP2,EXOSC6,NRAS,RAB7A,ARHGAP45,PPIE,CYSTM1,PSMB7,ATP6V0A1,RAB5B,TOLLIP,ALDH3B1,DSN1,AGPAT2,DDOST,SURF4,RAB24,STAT6,PSMD3,CAB39,CANT1,ATP6V0C,TICAM1,ROCK1,PDXK,LTA4H,MAPK1,CAPN1,TUBB,SVIP,MIF,DNAJC5,GMFG,MANBA,PDAP1,LAMTOR3,B4GALT1,ASAH1,CDK13,MAN2B1,NOTCH2,EIF2AK4,RAB6A,DOCK11,PSEN1,TMEM179B,GNS,CD59,PSMD2,IRF4,CTSS,ARPC5,HUWE1,MSH2,OSTF1,CNN2,MVP,STAT3,LPCAT1,MSH6,SPTAN1,CYFIP1,FTL,MLEC,RHOA,CREG1,MFNG,ITM2A,HEBP2,C1orf35,PKM,ARMC8,CCT8,NEU1,HSPA1B,PI4K2A,CAND1,XRCC5,CAT,RAB18,TSC1,ATP6V1D,MAGT1,GOLGA7,SNAP29,SNAP23,ACLY,PGRMC1,IMPDH1,CTSA,PSAP,GPI,PGAM1 |
| 3.351e-04 | -8.00 | PSMD6 (proteasome 26S subunit, non-ATPase 6) | protein interactions | 9861 | 99 | 30 | 17029 | 2761 |
TELO2,PSMA8,ATG9A,PSMB7,PSMA1,BRCA1,MCFD2,ZFAND5,PSMD9,PSMB9,PSMB3,UBLCP1,PSMC4,RAD23A,PTPN2,PSMD2,PSMA6,TIMM13,PSMD1,HUWE1,UCHL5,PSMD8,PSMD3,USP20,UBE3C,AHCYL1,PSMC1,VPS29,KDELR1,SSRP1 |
| 3.351e-04 | -8.00 | TIMM50 (translocase of inner mitochondrial membrane 50) | protein interactions | 92609 | 99 | 30 | 17029 | 2761 |
WASF2,CYFIP1,PHB2,SUZ12,RAF1,TCF3,MAGED1,GNE,CUL3,CUL1,CHCHD2,NDUFA4,NFATC2,NCKAP1,ADRB2,SRSF5,TOMM40,CYFIP2,MCM2,SDHA,SDHB,TIMM13,SHC1,SYNCRIP,ZNF746,PELO,FUS,SMURF1,CTDSP2,ABI1 |
| 3.357e-04 | -8.00 | CAFFAREL_RESPONSE_TO_THC_8HR_5_DN | MSigDB lists | CAFFAREL_RESPONSE_TO_THC_8HR_5_DN | 11 | 7 | 17377 | 2626 |
RRM2,HSPH1,SRSF3,DNAJA1,DNAJB1,PABPC4,RDH11 |
| 3.363e-04 | -8.00 | PRKCZ (protein kinase C zeta) | protein interactions | 5590 | 117 | 34 | 17029 | 2761 |
TRIM41,FEZ2,CASP6,PRKCSH,DYNLL1,RAF1,HABP4,PAWR,PSEN1,GLRX3,CDC42,MSH2,MSH6,CFL1,PDPK1,PPP3CA,RHOA,VHL,AKT2,NFATC2,APPL1,FADD,DAPK3,NMT2,MAPK3,JAK1,STAT6,YWHAZ,YWHAH,NIPSNAP2,MAPK1,HRAS,NUMB,PARD3 |
| 3.385e-04 | -7.99 | GSE13484_12H_VS_3H_YF17D_VACCINE_STIM_PBMC_DN | MSigDB lists | GSE13484_12H_VS_3H_YF17D_VACCINE_STIM_PBMC_DN | 185 | 46 | 17377 | 2626 |
CCDC93,REPS2,B4GALT5,TSC22D3,TMX4,ARID5A,AP3M2,B4GALT1,CYCS,RLF,RUFY1,RNF103,PRNP,AHCTF1,SP100,KLHL20,RAB4A,ZNF200,ECD,MARCH2,STAT3,SEH1L,HNRNPM,S100A6,VOPP1,BAK1,DEAF1,MAPRE2,TMEM39A,BTAF1,PARP4,RPL8,MTX1,PITPNB,DNAJA1,PICALM,MTR,RPSA,ATP1A1,KPNA1,SYNCRIP,MAGT1,SEL1L,KLHDC4,PSAP,TFDP2 |
| 3.385e-04 | -7.99 | GSE17721_CTRL_VS_POLYIC_2H_BMDC_UP | MSigDB lists | GSE17721_CTRL_VS_POLYIC_2H_BMDC_UP | 185 | 46 | 17377 | 2626 |
TCF3,SLC39A13,THRAP3,AP1B1,C19orf48,EXT2,ZBTB45,RAP1A,IARS,KLF16,DAD1,BDH1,TTC3,FBL,AHCYL1,PLCL2,CNPY3,NSUN4,TK1,ERMP1,ZFP64,GUK1,TIMMDC1,AKT2,SELPLG,OXR1,GBA,USP10,FBXO9,GLO1,MTX1,MEN1,DDX39A,PRPSAP1,STK17B,ZFR,SLC19A1,NUCB1,CDC16,QRSL1,NCOA1,MYL12B,FAF1,TUBB,HIGD2A,CCDC137 |
| 3.385e-04 | -7.99 | GSE5503_MLN_DC_VS_SPLEEN_DC_ACTIVATED_ALLOGENIC_TCELL_DN | MSigDB lists | GSE5503_MLN_DC_VS_SPLEEN_DC_ACTIVATED_ALLOGENIC_TCELL_DN | 185 | 46 | 17377 | 2626 |
ZNF296,HSPH1,DHPS,URB2,POC1A,YTHDC2,DBF4,CSNK2A1,SUMF1,PAIP1,RB1,PSMD2,MLX,MED10,STRBP,RAB35,ARF5,MBD2,MCPH1,N4BP2,MOB4,ANKRD37,KIAA0040,DENND1B,RAD51AP1,POLR2D,KRAS,FXR1,CCT8,APPL1,AKAP1,EPRS,RAD51C,MTHFD2,PPM1G,FAM3C,MEGF9,PPP1R11,STK11,PRPF4,BEND3,ATP6V1C1,REEP4,CHID1,BYSL,PRPF4B |
| 3.385e-04 | -7.99 | GSE17301_CTRL_VS_48H_ACD3_ACD28_IFNA2_STIM_CD8_TCELL_DN | MSigDB lists | GSE17301_CTRL_VS_48H_ACD3_ACD28_IFNA2_STIM_CD8_TCELL_DN | 185 | 46 | 17377 | 2626 |
HJURP,CLSPN,DEPDC1,FOXM1,PTTG1,CDCA3,EPN1,SLC29A1,CDKN2C,SLC1A4,HDAC7,DAPK1,CNPY4,GTSE1,MAST2,CENPM,F2R,MICAL3,ORAI2,TK1,PRRC2A,ZNF500,CIC,MYBL2,E2F3,SEPT8,RRM2,NUSAP1,BRCA1,PKMYT1,TOMM40,CCNF,RHOT2,SPPL2B,ASF1B,HMGN2,HSPBP1,FASTK,E2F1,STK11,HMGB2,SCARB1,WDR62,NUDT11,CCNB2,AAAS |
| 3.386e-04 | -7.99 | SA_B_CELL_RECEPTOR_COMPLEXES | MSigDB lists | SA_B_CELL_RECEPTOR_COMPLEXES | 24 | 11 | 17377 | 2626 |
VAV1,SHC1,RPS6KA1,VAV2,RAC1,ELK1,ATF2,LYN,MAPK1,HRAS,MAPK3 |
| 3.386e-04 | -7.99 | GOLUB_ALL_VS_AML_UP | MSigDB lists | GOLUB_ALL_VS_AML_UP | 24 | 11 | 17377 | 2626 |
PSMA6,DHPS,DYNLL1,TCF3,SMARCA4,TOP2B,ACADM,CYFIP2,RBBP4,STMN1,MYL6B |
| 3.386e-04 | -7.99 | REACTOME_SEMA4D_INDUCED_CELL_MIGRATION_AND_GROWTH_CONE_COLLAPSE | MSigDB lists | REACTOME_SEMA4D_INDUCED_CELL_MIGRATION_AND_GROWTH_CONE_COLLAPSE | 24 | 11 | 17377 | 2626 |
RHOG,RHOA,CDC42,LIMK1,RHOC,RAC1,MYH9,ARHGEF12,ROCK1,MYL12B,RHOB |
| 3.390e-04 | -7.99 | AIFM1 (apoptosis inducing factor mitochondria associated 1) | protein interactions | 9131 | 108 | 32 | 17029 | 2761 |
CYLD,SUZ12,TOR1AIP1,XIAP,PMS2,CUL1,PTP4A3,SHC1,MEX3C,THAP4,PELO,ZNF746,APOOL,STAU1,PTPN18,NOA1,CPOX,CUL3,TUFM,NFATC2,ADRB2,VDAC1,TOMM40,SLC25A5,EIF3G,GFER,CAND1,HSPA1B,TONSL,H2AFX,NDUFS5,NR2F2 |
| 3.396e-04 | -7.99 | Hurthle_cell_adenoma | COSMIC cancer mutations | Hurthle_cell_adenoma | 28 | 12 | 17385 | 2587 |
FGFR3,PCM1,NRAS,CCDC6,PTEN,KRAS,MEN1,TFG,ERC1,KTN1,SMAD4,HRAS |
| 3.396e-04 | -7.99 | thyroid-adenoma-nodule-goitre-Hurthle_cell_adenoma | COSMIC cancer mutations | thyroid-adenoma-nodule-goitre-Hurthle_cell_adenoma | 28 | 12 | 17385 | 2587 |
FGFR3,PCM1,NRAS,CCDC6,PTEN,KRAS,MEN1,TFG,ERC1,KTN1,SMAD4,HRAS |
| 3.398e-04 | -7.99 | DNA damage response, detection of DNA damage | biological process | GO:0042769 | 39 | 15 | 17256 | 2622 |
DTL,RPA2,RFC3,NEK1,PCNA,RAD18,RBX1,RPS27A,MRPS26,DNAJA1,SOX4,RFC2,DDB1,WDR48,RPA1 |
| 3.399e-04 | -7.99 | IBTK (inhibitor of Bruton tyrosine kinase) | protein interactions | 25998 | 73 | 24 | 17029 | 2761 |
SRP72,RFC3,RBX1,POC1A,RPL6,LACTB,CUL3,LAMTOR3,USP10,KRAS,PCGF1,RGS2,RPS9,CAND1,DOT1L,PCM1,CENPJ,ODF2,POP7,RPLP1,FTSJ1,CD81,ESPL1,PDCD4 |
| 3.399e-04 | -7.99 | NAT10 (N-acetyltransferase 10) | protein interactions | 55226 | 73 | 24 | 17029 | 2761 |
NOL12,RPS2,NOP2,ZNF512,SUZ12,MECP2,ABCF2,CUL3,CUL1,BRCA1,UBE2I,CAND1,LYAR,UTP20,MDM2,C1orf131,SYNCRIP,DGCR8,MCM5,RPS14,TFG,IFI16,GPATCH4,CDC5L |
| 3.399e-04 | -7.99 | RBM25 (RNA binding motif protein 25) | protein interactions | 58517 | 73 | 24 | 17029 | 2761 |
SRSF11,SART1,BRD4,PRKDC,RNPS1,SREK1,JMJD6,PRPF3,SEPT7,CDK11B,UBE2I,LUC7L,CDK11A,RPA1,SUPT16H,RPA2,RBM23,NEIL3,MSH2,TCEA1,CFAP20,IFI16,HNRNPM,PRPF19 |
| 3.399e-04 | -7.99 | TSC2 (TSC complex subunit 2) | protein interactions | 7249 | 73 | 24 | 17029 | 2761 |
PLK1,TK1,TSC2,PRKCSH,RPS6KA1,PRKAA1,RRAGC,RHEB,MAPK3,PPP2CA,TSC1,RAP1A,SMAD2,NEK1,TIGAR,AXIN1,PIN1,DAPK1,CDKN1B,YWHAZ,RP2,RUVBL2,MAPK1,YWHAH |
| 3.401e-04 | -7.99 | Cellular response to heat stress | REACTOME pathways | R-HSA-3371556 | 89 | 28 | 10287 | 1696 |
DNAJC2,HSPH1,NDC1,NUP188,ST13,RAE1,NUP54,NUP155,AKT1S1,DNAJB1,NUP205,HSPA1B,MAPK3,RPA1,RPA2,NUP210,HSPA4,NUP107,NUP62,NUP153,PTGES3,MAPK1,NUP85,NUP58,AAAS,CAMK2G,SEH1L,MLST8 |
| 3.403e-04 | -7.99 | GO_RESPONSE_TO_RADIATION | MSigDB lists | GO_RESPONSE_TO_RADIATION | 394 | 85 | 17377 | 2626 |
NPHP4,DNMT3A,TXN,NF1,TMEM109,BCL2L1,IKBIP,MAPK14,RPAIN,APP,RBM4,MBD4,CDK5,USF1,MDM2,PCNA,MTA1,XRCC2,DNM2,NOC2L,CRY2,OGG1,DNMT1,PTPRK,PLK3,BAK1,DEAF1,ERCC1,PBK,RAD51AP1,CIRBP,AURKB,BRCA1,DCLRE1C,TANC1,RAD54B,MAP3K4,RAD51C,RAD18,H2AFX,ITGB1,STK11,XRCC3,TRIM32,CLU,CHEK2,FBXL3,XRCC4,RAD51D,EYA1,MECP2,BABAM1,PRKAA1,RRM1,EIF2AK4,BLM,RHBDD1,RFWD3,DTL,INTS7,XPA,MSH2,BCL2,CREB1,GTF2H2,EEF1D,MSH6,TGFB1,NET1,PRKDC,MAP4K3,KRAS,UBE4B,MEN1,ELK1,RHOB,XRCC5,RDH11,CAT,PML,AEN,RUVBL2,YY1,IFI16,DDB1 |
| 3.406e-04 | -7.98 | TCCAGAT,MIR-516-5P | MSigDB lists | TCCAGAT,MIR-516-5P | 101 | 29 | 17377 | 2626 |
SNX27,BRD4,OAF,TLK1,MIER1,OLA1,GMFB,PLAGL2,FRAT2,B4GALT1,LRRC8A,ATXN1,ARGLU1,ARHGEF12,NUTF2,SRSF5,ASXL2,AKAP1,GNAS,ZNF282,MID1IP1,ATP2A2,ZNRF2,TAB2,NCOA1,STAT3,TIMM50,RYBP,ATXN7L2 |
| 3.406e-04 | -7.98 | GO_PIGMENT_GRANULE | MSigDB lists | GO_PIGMENT_GRANULE | 101 | 29 | 17377 | 2626 |
PPIB,ANKRD27,DNAJC5,PDCD6IP,ANXA6,RAB7A,RAC1,SLC2A1,FLOT1,ATP6V0A1,SND1,RAB1A,ATP6V1B2,RAB5B,TFRC,PRDX1,RPN1,NAP1L1,ATP1A1,SLC1A4,TMED10,RAB35,ITGB1,YWHAZ,AHCY,PDIA6,ANXA11,MYO5A,TMEM33 |
| 3.408e-04 | -7.98 | Orc1 removal from chromatin | REACTOME pathways | R-HSA-68949 | 72 | 24 | 10287 | 1696 |
PSMA8,CDT1,PSMB7,PSMA1,CDC6,ORC1,MCM2,PSMD9,PSMB9,PSMB3,PSMC4,PSMD2,RB1,PSMA6,CCNA2,PSMD1,RPS27A,PSMD8,PSMD3,MCM5,CDKN1B,ORC3,CDK2,PSMC1 |
| 3.408e-04 | -7.98 | Switching of origins to a post-replicative state | REACTOME pathways | R-HSA-69052 | 72 | 24 | 10287 | 1696 |
PSMA8,CDT1,PSMB7,PSMA1,CDC6,ORC1,MCM2,PSMD9,PSMB9,PSMB3,PSMC4,PSMD2,RB1,PSMA6,CCNA2,PSMD1,RPS27A,PSMD8,PSMD3,MCM5,CDKN1B,ORC3,CDK2,PSMC1 |
| 3.408e-04 | -7.98 | JIANG_VHL_TARGETS | MSigDB lists | JIANG_VHL_TARGETS | 125 | 34 | 17377 | 2626 |
RAB14,EWSR1,TRIP10,FAM53C,RPS6KA1,ANKH,SLC39A13,TBC1D13,BRIX1,RAB11A,C12orf10,PCNA,AHDC1,GM2A,KDELR1,NIPSNAP1,RPL29,TSTA3,GMFB,MKI67,FXR1,EIF3G,RHOB,HMGN2,INF2,SCARB2,AHNAK,HSPB11,APPL2,PITRM1,PGAM1,CDK2,CAPN1,LRCH1 |
| 3.415e-04 | -7.98 | Nuclear pore complex | KEGG pathways | hsa_M00427 | 45 | 17 | 7161 | 1149 |
NDC1,NUP188,RAE1,SUMO2,NUP54,NUP155,RANGAP1,UBE2I,NUP205,NUP210,NUP107,NUP62,NUP153,NUP58,NUP85,AAAS,SEH1L |
| 3.415e-04 | -7.98 | Nuclear pore complex | KEGG pathways | M00427 | 45 | 17 | 7161 | 1149 |
NDC1,NUP188,RAE1,SUMO2,NUP54,NUP155,RANGAP1,UBE2I,NUP205,NUP210,NUP107,NUP62,NUP153,NUP58,NUP85,AAAS,SEH1L |
| 3.416e-04 | -7.98 | GO_HEAT_SHOCK_PROTEIN_BINDING | MSigDB lists | GO_HEAT_SHOCK_PROTEIN_BINDING | 87 | 26 | 17377 | 2626 |
BAK1,TELO2,DNAJC2,NASP,ST13,DNAJB2,CSNK2A1,DNAJC9,DNAJA1,DNAJB1,OGDH,TFRC,HSPA1B,DNAJC10,PDXP,LIMK1,ARNTL,CDKN1B,NUP62,FKBP5,CREB1,PPP5C,FAF1,HDAC2,EEF1D,CDC37 |
| 3.420e-04 | -7.98 | Znf_FYVE_PHD | interpro domains | IPR011011 | 136 | 36 | 18492 | 2768 |
ASH1L,KMT2E,PHF23,KDM4A,SHPRH,PHRF1,CXXC1,ZFYVE21,NSD3,RUFY1,TCF19,KDM2A,SP100,BRPF3,MTMR4,PHF14,INTS12,ZFYVE27,PIKFYVE,FBXL19,SYTL3,PHF20L1,PHF10,BAZ2A,ZMYND11,RFFL,DIDO1,KMT2C,TRIM28,PLEKHF2,MTMR3,HGS,CHD3,UHRF2,KMT2B,BAZ1B |
| 3.430e-04 | -7.98 | GO_NEGATIVE_REGULATION_OF_DNA_RECOMBINATION | MSigDB lists | GO_NEGATIVE_REGULATION_OF_DNA_RECOMBINATION | 14 | 8 | 17377 | 2626 |
TERF2IP,THOC1,HELB,MSH2,BLM,MSH6,TERF2,POLQ |
| 3.430e-04 | -7.98 | GO_ACTIVATION_OF_ANAPHASE_PROMOTING_COMPLEX_ACTIVITY | MSigDB lists | GO_ACTIVATION_OF_ANAPHASE_PROMOTING_COMPLEX_ACTIVITY | 14 | 8 | 17377 | 2626 |
PLK1,GOLGA2,PTEN,GORASP1,RAB1A,UBE2C,MASTL,FBXO5 |
| 3.430e-04 | -7.98 | MATTIOLI_MGUS_VS_MULTIPLE_MYELOMA | MSigDB lists | MATTIOLI_MGUS_VS_MULTIPLE_MYELOMA | 14 | 8 | 17377 | 2626 |
EZR,NUP62,SEC23IP,PREPL,PRDX3,GADD45B,LPCAT4,DDX17 |
| 3.430e-04 | -7.98 | REACTOME_VIRAL_MESSENGER_RNA_SYNTHESIS | MSigDB lists | REACTOME_VIRAL_MESSENGER_RNA_SYNTHESIS | 14 | 8 | 17377 | 2626 |
POLR2I,POLR2G,POLR2L,POLR2J,POLR2K,POLR2A,GTF2F1,POLR2D |
| 3.430e-04 | -7.98 | PID_TCR_RAS_PATHWAY | MSigDB lists | PID_TCR_RAS_PATHWAY | 14 | 8 | 17377 | 2626 |
NRAS,RAF1,PTPN7,KRAS,ELK1,MAPK1,HRAS,MAPK3 |
| 3.435e-04 | -7.98 | GSE22611_UNSTIM_VS_2H_MDP_STIM_MUTANT_NOD2_TRANSDUCED_HEK293T_CELL_UP | MSigDB lists | GSE22611_UNSTIM_VS_2H_MDP_STIM_MUTANT_NOD2_TRANSDUCED_HEK293T_CELL_UP | 180 | 45 | 17377 | 2626 |
NADSYN1,GCLM,TXN,PRKCSH,TOR3A,UFC1,CIB1,SNN,DUSP22,PSMD9,SDHA,CD59,DPYSL2,SIVA1,ARHGEF1,PTPN11,FBXW2,ANXA5,GLTP,MAST2,ARL5A,UBE2M,ALDH9A1,CSTF1,ADCY7,RPAP3,IFRD1,ELOVL5,AATF,TSPYL4,ERLIN1,KCTD20,SLBP,PRPF3,BORA,BTBD1,PRDM11,ELMO1,DCK,PPP1R11,SLC16A1,MAP3K5,TOB1,RNF139,DDB1 |
| 3.435e-04 | -7.98 | GSE33424_CD161_HIGH_VS_INT_CD8_TCELL_DN | MSigDB lists | GSE33424_CD161_HIGH_VS_INT_CD8_TCELL_DN | 180 | 45 | 17377 | 2626 |
NDUFA5,PKP4,TXN,NDUFB6,CUTA,UCK2,CDCA3,FLOT1,CSNK2A1,RACGAP1,NCKAP1,SPR,STMN1,BZW2,CCNA2,NDUFA2,MRPL54,FOXN2,KIF22,AHCY,METTL9,F2R,PPA1,S100A6,SELPLG,EMB,MYBL2,ITM2A,NUSAP1,GALK2,MCM2,GOSR1,MRPS14,MTR,FAS,PDLIM1,VPS26B,MRPL27,RWDD4,PGAM1,CCNB2,RPS26,PFKP,TUBB,PTOV1 |
| 3.435e-04 | -7.98 | GSE2770_UNTREATED_VS_TGFB_AND_IL4_TREATED_ACT_CD4_TCELL_2H_UP | MSigDB lists | GSE2770_UNTREATED_VS_TGFB_AND_IL4_TREATED_ACT_CD4_TCELL_2H_UP | 180 | 45 | 17377 | 2626 |
IMMT,MRPS2,UFC1,SCYL1,GNE,SND1,DCUN1D4,SPR,TMEM165,SSR1,SLC31A1,PSMD1,ZNF473,EIF2S2,NEK6,DNAAF2,ZNF260,MRPL54,AP2B1,PARL,SLC38A10,ECD,ALDH18A1,SGCB,TMEM9,TMBIM1,IMPA2,MED22,TIMM8B,LARS,DDX28,SIGMAR1,OXR1,SCFD2,SEPT8,PEF1,RHOB,NUCB1,ALDH3B1,PON2,IDE,MRFAP1L1,CLU,CHPF2,PDSS2 |
| 3.435e-04 | -7.98 | GSE12366_PLASMA_CELL_VS_NAIVE_BCELL_DN | MSigDB lists | GSE12366_PLASMA_CELL_VS_NAIVE_BCELL_DN | 180 | 45 | 17377 | 2626 |
WASF2,RAB14,GMFG,ACTR3,MYH9,PAWR,TGOLN2,SNN,RPL23A,CRKL,PHC2,ADD3,CCDC50,PTEN,MCM5,BANF1,BTF3L4,GM2A,CFL1,LARS,PPP1R18,APH1A,RAD51AP1,ERLIN1,PGS1,ZNF512,RPL38,DCLRE1C,ARID1A,DHX15,ARHGAP15,RPL36,SUPT16H,SRSF1,OSBPL11,FBXO41,SERTAD2,ATAD2,RPS27A,HNRNPR,UBXN2B,RBMS1,CHMP7,C7orf26,ZC3HAV1 |
| 3.435e-04 | -7.98 | GO_TRANS_GOLGI_NETWORK | MSigDB lists | GO_TRANS_GOLGI_NETWORK | 180 | 45 | 17377 | 2626 |
RAB14,CORO7,GOLPH3L,SYS1,SCOC,ADAM10,TRIP10,RAC1,VTI1A,ARFIP2,TGOLN2,RAB6A,ARF1,AP1B1,GGA2,BECN1,TMEM165,RAB11A,APP,RAB21,KLHL20,AP1M1,DNM2,AP2B1,CLTB,GCC2,TRAPPC9,RHOBTB3,ATG9A,LAP3,NCK1,ATP2C1,COG1,AP4E1,STX16,OPTN,GNAS,NUCB1,GOLGA4,MYO18A,ARAP1,AP1S1,SMPD4,CLN3,CHID1 |
| 3.435e-04 | -7.98 | SPTAN1 (spectrin alpha, non-erythrocytic 1) | protein interactions | 6709 | 178 | 47 | 17029 | 2761 |
KARS,MAPRE1,CYLD,EWSR1,NUP188,ADD1,DHX9,MYH9,CUL1,NENF,RPA2,SHC1,EIF4A3,PTEN,PPP4R1,RPN2,CEP63,ABI1,CDC5L,STAU1,DDX24,STRIP1,CUL3,RPS24,BRCA1,DNAJA1,CAPZA2,PLEC,TANC1,ANLN,STYXL1,EPB41,RPA1,HNRNPR,MAPK6,MYO18A,STAT1,ACTB,FAU,CDK2,ARRB2,ECPAS,SMURF1,TERF1,POT1,CAPN1,PTOV1 |
| 3.440e-04 | -7.97 | precatalytic spliceosome | cellular component | GO:0071011 | 44 | 16 | 18223 | 2701 |
PRPF38B,SART1,SNRPB,SF3B1,SF3B6,SMU1,CRNKL1,LSM8,PRPF3,SNRPD3,SF3B2,NSRP1,PRPF4,SNRPG,SNRNP70,WDR62 |
| 3.476e-04 | -7.96 | GCACTTT,MIR-17-5P,MIR-20A,MIR-106A,MIR-106B,MIR-20B,MIR-519D | MSigDB lists | GCACTTT,MIR-17-5P,MIR-20A,MIR-106A,MIR-106B,MIR-20B,MIR-519D | 563 | 115 | 17377 | 2626 |
HECA,LUZP1,TRIP10,RPS6KA1,PLAGL2,YTHDF3,TGOLN2,PLXNA1,DAZAP2,APP,PAPOLA,ANKRD28,AHCTF1,KDM2A,DPYSL2,JAZF1,PPP6C,SOCS6,DNM2,JOSD1,ANKRD13C,CRY2,ANKRD9,SENP1,ZNF800,ARID4A,TIMP2,CELSR2,E2F3,RRM2,ATXN1,TOPORS,MCL1,MIER2,BICD2,SOX4,TANC1,RAB5B,RAB22A,SERP1,GIGYF1,PAF1,RBL1,CERS6,LIMK1,STK38,FASTK,ZNF367,ADAM9,KPNA2,SLC22A23,ABCA1,DYNC1LI2,POLQ,KIF3B,MAPRE1,MECP2,RHOC,ZFP91,HABP4,KIF23,SUMF1,SIKE1,EZH1,DNAJB9,NPLOC4,MAT2B,RB1,LHX8,UBE2Q2,ITGB8,KLHL20,PTEN,FJX1,SS18L1,UBE3C,MAP3K14,ST8SIA2,STAT3,SMC4,ABHD2,PPP3CA,RB1CC1,C16orf72,CIC,DCAF8,PPP1R21,OXR1,GOSR1,EIF4H,EIF4G2,PHF6,MASTL,MTMR3,SH3BP5,TMEM127,FBXO21,SERTAD2,ATAD2,TMEM168,L3MBTL3,CSNK1G1,USP32,E2F1,PPP3R1,PKD2,DDX5,CNOT6,RGL1,MAP3K5,PPP6R2,PPP6R3,BTBD10,PURA,NIPA1 |
| 3.479e-04 | -7.96 | HOXA9_DN.V1_DN | MSigDB lists | HOXA9_DN.V1_DN | 175 | 44 | 17377 | 2626 |
TMEM106C,MCM10,C1orf112,TSC22D3,CDT1,GMCL1,SLC29A1,NOTCH2,ORC1,ITGB5,STAM,CPNE3,FZD6,FANCI,RGS1,RFWD3,FANCL,CCNK,RB1,NFATC3,SAR1A,CD3EAP,SCAMP4,RNASEH2A,LMAN1,SLC25A1,GINS1,RHOBTB3,PRIM2,HMGN5,NET1,WBP2,KCTD20,CDC6,NUTF2,MEN1,ECH1,GINS4,RBM38,HHEX,ATAD2,PTER,CEP55,FKBP5 |
| 3.479e-04 | -7.96 | GSE26928_NAIVE_VS_EFF_MEMORY_CD4_TCELL_DN | MSigDB lists | GSE26928_NAIVE_VS_EFF_MEMORY_CD4_TCELL_DN | 175 | 44 | 17377 | 2626 |
WSB2,HIVEP3,PRKAB1,RECQL,FEZ2,CDS2,TXN,TSC22D3,RAC1,BCL2L1,SRRT,LMNA,SPPL2A,GNS,DTL,ATP2A2,DPYSL2,CENPJ,RABGAP1L,CRAT,FBXO7,SRI,GLTP,F2R,TMX1,CLPTM1,SRP72,SNRNP200,NASP,FAM49B,PIGT,ELL2,TMEM216,SLBP,PFKFB3,ADRB2,ODC1,NEU1,SLCO4A1,KEAP1,DGCR8,NDUFA11,PITPNA,ZSWIM6 |
| 3.479e-04 | -7.96 | GSE2770_TGFB_AND_IL4_VS_TGFB_AND_IL12_TREATED_ACT_CD4_TCELL_2H_DN | MSigDB lists | GSE2770_TGFB_AND_IL4_VS_TGFB_AND_IL12_TREATED_ACT_CD4_TCELL_2H_DN | 175 | 44 | 17377 | 2626 |
WSB2,PPIB,UNK,DDX47,LYRM4,ZCCHC9,MRPL42,SEC61G,NUP54,JMJD6,PLXNA1,CUTC,MRPL19,WWP2,CLIC4,CCP110,CAPZA1,NAA50,ATP6V0A2,DCP1A,UBE3C,GTF2H2,CDC37,PPIF,MLEC,HMGN5,TACC1,ABCF2,NSUN2,CYP20A1,VDAC1,ZFAND5,EIF4G2,DOT1L,DNAJC10,SYNCRIP,PFDN4,LSM6,PTPN7,FTSJ1,YWHAH,ATP6V0E1,TERF1,SLC25A33 |
| 3.479e-04 | -7.96 | GSE19825_NAIVE_VS_IL2RALOW_DAY3_EFF_CD8_TCELL_DN | MSigDB lists | GSE19825_NAIVE_VS_IL2RALOW_DAY3_EFF_CD8_TCELL_DN | 175 | 44 | 17377 | 2626 |
ZNF296,KDM4A,SEC61G,URB2,GADD45G,TRAK1,VTI1A,JMJD6,CLCC1,SAFB2,FBXO5,PRNP,CENPJ,TXLNA,PDCD2,ZBTB22,CYB5R1,POLR1B,ERI3,LPCAT1,GNAI2,CLN6,TPCN1,TGFB1,CLPTM1,GTF3C6,ERCC1,ZNF672,ERMP1,DENND1B,MTA2,PRKDC,BTAF1,SREK1,PRKRA,PRDX1,FAS,NECAP2,C1orf122,RAD51C,LSM6,CHCHD1,TAF6,GEN1 |
| 3.479e-04 | -7.96 | BYSTRYKH_HEMATOPOIESIS_STEM_CELL_AND_BRAIN_QTL_TRANS | MSigDB lists | BYSTRYKH_HEMATOPOIESIS_STEM_CELL_AND_BRAIN_QTL_TRANS | 175 | 44 | 17377 | 2626 |
MIF,TRIP12,NF1,SLC2A1,CTCF,PXMP2,NANS,BLM,PDXDC1,MRPL50,RPN1,MED10,C4orf3,DAD1,DDA1,AKAP8,TPST1,ANP32A,SLC38A10,AHCY,TTC17,SLC35C2,TIPARP,PRPF19,PGAP2,SGCE,TK1,MKLN1,SNRPB,MKI67,ZNF574,VDAC2,USP22,SF3A2,XRCC5,NEK1,PDLIM1,CCDC6,RPLP1,BAZ1B,STK11,NCOA1,ABCA1,S100PBP |
| 3.483e-04 | -7.96 | MRPL9 (mitochondrial ribosomal protein L9) | protein interactions | 65005 | 86 | 27 | 17029 | 2761 |
DDX28,MRPL42,MRPL39,MRPL12,MRPL43,RPL6,ILF3,NLN,MRPL16,EIF4H,MRPL19,CAND1,MRPL50,MRPL2,MRPL55,NSF,MRPL27,MRPL34,MRPL54,MRPL40,MRPL48,MRPL11,MRPL21,MRPL13,MRPL3,ZC3H3,MRPL32 |
| 3.483e-04 | -7.96 | EIF3C (eukaryotic translation initiation factor 3 subunit C) | protein interactions | 8663 | 86 | 27 | 17029 | 2761 |
EIF3L,CYLD,GPBP1L1,EIF3D,RPL8,CUL3,MYH9,CSNK2A1,RPS24,KRAS,MCM2,EIF3G,PDHX,EIF3H,EIF3A,CHAF1A,EIF3K,MRPL2,NAP1L1,TMED10,MAPK6,USP20,TARDBP,NAP1L4,CDK2,CD81,ABCC1 |
| 3.512e-04 | -7.95 | spindle midzone | cellular component | GO:0051233 | 32 | 13 | 18223 | 2701 |
PLK1,CTDP1,KIF18A,PKP4,CDC42,KIF18B,KIF14,CDCA8,CCDC69,CDC6,RACGAP1,AURKB,APP |
| 3.516e-04 | -7.95 | AR (androgen receptor) | protein interactions | 367 | 307 | 73 | 17029 | 2761 |
USP7,KARS,REPS2,KDM4A,SUZ12,RAF1,SMARCA4,UBE2I,PARK7,PA2G4,MDM2,IARS,IL6ST,CDC25B,ATF2,SMARCE1,CTDSP2,CDC37,AATF,VHL,KAT7,BRCA1,PPP2CA,DAP3,IDE,RBL1,TAB2,E2F4,FKBP5,ACTB,RNASEL,NCOA1,SMAD1,PPP5C,MAPK1,SMAD4,NCOR2,COX5B,ARID5A,ETS1,ARID1B,WDR48,GTF2F1,RB1,SUV39H2,PTEN,HDAC7,KIFAP3,PTGES3,STAT3,GTF2H2,NCOA2,DCAF6,PRKDC,PSPC1,RCOR1,USP10,ARID1A,KDM3A,APPL1,DAPK3,XRCC5,PIAS2,E2F1,SIAH2,HMGB2,NDE1,ZMIZ1,RNF14,HIPK3,APOL2,IFI16,SMARCD1 |
| 3.517e-04 | -7.95 | GSE9988_LOW_LPS_VS_ANTI_TREM1_AND_LPS_MONOCYTE_DN | MSigDB lists | GSE9988_LOW_LPS_VS_ANTI_TREM1_AND_LPS_MONOCYTE_DN | 170 | 43 | 17377 | 2626 |
GNPDA1,KLHL21,RRAGC,DCUN1D4,ATP6V1B2,RLF,RGS1,SPAG5,ANKRD28,MOAP1,DTL,SNUPN,THAP4,ZCCHC2,NAA50,BRI3,FNIP2,RNF19A,RBM15,ATP6V1G1,SNX8,RHOBTB3,TCTEX1D2,LONRF3,NUDT4,ACSL3,TEX10,MAP4K3,RHOB,NEU1,PI4K2A,ANKRD10,SH3BP5,SCARB2,SLCO4A1,SERTAD2,ATP6V1D,PPP2R5A,CORO1C,MAFK,WDR91,USP53,ZC3HC1 |
| 3.521e-04 | -7.95 | KAAB_FAILED_HEART_ATRIUM_DN | MSigDB lists | KAAB_FAILED_HEART_ATRIUM_DN | 135 | 36 | 17377 | 2626 |
TXN,LAGE3,GLUD1,GTF3A,UBE2I,PSMD9,APP,PAPOLA,FKBP1A,CD59,CLIC4,SRI,EI24,UBE3C,SPTSSA,STAT3,MLEC,AMD1,LRBA,LDHA,TMEM147,NUTF2,RIT1,RAB1A,PRDX1,PSMB3,RPA1,OPTN,PDCD6,CDC16,HINT1,TMED10,CAPN7,YWHAZ,ACTB,ATP6V0E1 |
| 3.521e-04 | -7.95 | RB_P107_DN.V1_UP | MSigDB lists | RB_P107_DN.V1_UP | 135 | 36 | 17377 | 2626 |
RRM1,STMN1,TCF19,FANCL,RPA2,PCNA,MCM5,SIVA1,PRC1,GTSE1,CDC25B,NXT1,RFC3,PRIM2,WDHD1,DNAJC9,SLBP,RRM2,MCM2,CCNF,H2AFV,RFC2,ASF1B,GINS4,HAUS8,PRIM1,HMGN2,RPA1,POLE,NSMCE2,NRM,E2F1,PML,CDK2,CD81,RHEBL1 |
| 3.528e-04 | -7.95 | protein phosphatase binding | molecular function | GO:0019903 | 109 | 31 | 17224 | 2647 |
ANKLE2,PPP1R9B,SHOC2,STRN4,ENSA,KCNQ1,PPP3CB,MAPK14,GTF2F1,MASTL,RPA2,MTMR3,CDC27,JAK1,CSK,MTMR4,PPME1,STAT6,PIK3R2,CDKN1B,PPP1R11,BCL2,ANAPC7,PPP6R3,MAP3K5,MVP,IGBP1,STAT3,PPP6R1,ANAPC4,PARD3 |
| 3.532e-04 | -7.95 | CAGTGTT,MIR-141,MIR-200A | MSigDB lists | CAGTGTT,MIR-141,MIR-200A | 296 | 67 | 17377 | 2626 |
TCF12,SNX27,H2AFZ,PPP1R15B,PLAGL2,KLHL18,YTHDF3,CSNK2A1,ATP6V1B2,SLC20A1,SEC11A,ATP2A2,SIAH1,WDR44,JAZF1,RAD23B,PDS5B,MTPN,SLC39A9,SLC16A7,CUL3,HNRNPF,E2F3,WIPF1,ATXN1,LRRC8A,BICD2,PITPNB,PPP2CA,PEX5,VPS26B,LUC7L3,ARNTL,OGT,RBMS1,ANP32E,FKBP5,DMWD,PDCD4,RMND5A,TM9SF4,MECP2,C16orf87,EPN1,MED13L,CDK13,PSEN1,CSNK1A1,HMG20A,TFRC,TNS3,RNFT1,ARPC5,PTGES3,CSNK1G3,YTHDC1,AMPD2,MAP7D1,RTF1,SEPT7,ZFR,TSC1,OSBPL11,SERF2,DUSP3,DDX5,TAF12 |
| 3.547e-04 | -7.94 | GSE34156_UNTREATED_VS_6H_TLR1_TLR2_LIGAND_TREATED_MONOCYTE_DN | MSigDB lists | GSE34156_UNTREATED_VS_6H_TLR1_TLR2_LIGAND_TREATED_MONOCYTE_DN | 165 | 42 | 17377 | 2626 |
CCDC93,RAB14,COX5B,ANKRD13D,RWDD1,ADO,DCTN2,CUTA,IRF3,MAPK14,TMEM165,APH1B,FAM8A1,CHKA,SRXN1,CDK5,CRAT,RAB35,LPCAT1,TMEM9,ASB6,TMED2,ATP6V1G1,LONRF3,LDB1,MAP2K2,PRDX1,USP36,EIF3A,FADD,RPL36,AKAP1,STOML2,PON2,TBC1D17,ITPRIPL1,BRWD1,FAM110A,DTX4,IMPDH1,SAMD8,DCAF5 |
| 3.560e-04 | -7.94 | ALDH18A1 (aldehyde dehydrogenase 18 family member A1) | protein interactions | 5832 | 37 | 15 | 17029 | 2761 |
STAU1,TIMM13,RALB,AGTRAP,UBR2,TCF3,ILF3,CUL3,TUBGCP5,CERK,DCP1A,NFATC2,ADRB2,ZRANB1,CDK2 |
| 3.560e-04 | -7.94 | HEPACAM2 (HEPACAM family member 2) | protein interactions | 253012 | 37 | 15 | 17029 | 2761 |
PTPRF,NAT14,RAB18,WDR44,UBR2,PIK3R2,MAP4K4,CERK,UPK3BL1,CYB5R1,EDEM2,EHD4,MAD2L2,CD320,RDH11 |
| 3.560e-04 | -7.94 | STT3B (STT3B, catalytic subunit of the oligosaccharyltransferase complex) | protein interactions | 201595 | 37 | 15 | 17029 | 2761 |
CLPTM1,RPN1,UNK,RPS15,MLEC,SYNCRIP,DDOST,MAGT1,RAB7A,CORO1C,TMEM216,RPN2,KRTCAP2,ABCC1,EVC2 |
| 3.568e-04 | -7.94 | LAIHO_COLORECTAL_CANCER_SERRATED_UP | MSigDB lists | LAIHO_COLORECTAL_CANCER_SERRATED_UP | 106 | 30 | 17377 | 2626 |
NDUFV2,ADAM10,RBX1,SUMO2,EMP3,CHMP2B,CSNK1A1,MRPS14,MACF1,OPTN,MBD4,PRNP,EPRS,SERF2,ORMDL2,DPYSL2,MFAP1,DAD1,RBM34,IL6ST,CAPZA1,ANXA5,ANP32E,BCAP29,TAGLN2,PDIA6,SGCB,PDLIM5,ATP6V0E1,MYL12B |
| 3.569e-04 | -7.94 | GSE40274_CTRL_VS_FOXP3_AND_LEF1_TRANSDUCED_ACTIVATED_CD4_TCELL_DN | MSigDB lists | GSE40274_CTRL_VS_FOXP3_AND_LEF1_TRANSDUCED_ACTIVATED_CD4_TCELL_DN | 160 | 41 | 17377 | 2626 |
GCLM,MCM10,UROD,GSPT2,NUP54,EPN1,AGPAT3,ABCB10,AKT1S1,TMED3,PMF1,SNRPD3,CSNK1A1,TUBGCP2,EDC3,EXOSC7,KIF14,DUT,MRPL34,CS,NDUFB9,TAF5L,PPA1,PBK,CPOX,PPIE,MKI67,CDC6,TMEM147,RIT1,SYMPK,ASF1B,UBTF,AEN,PIEZO1,PPP6R2,PPP5C,SLC22A23,RPS6KC1,RAB3IL1,SSRP1 |
| 3.569e-04 | -7.94 | GSE27291_0H_VS_6H_STIM_GAMMADELTA_TCELL_DN | MSigDB lists | GSE27291_0H_VS_6H_STIM_GAMMADELTA_TCELL_DN | 160 | 41 | 17377 | 2626 |
RWDD1,NDUFAF2,PDAP1,HABP4,EBNA1BP2,SECISBP2,THRAP3,ASXL2,RPAIN,CD320,CSDE1,PTEN,TIMM23,AXIN2,TRA2B,NDUFB9,AHCY,CYC1,ALDH18A1,AHCYL1,LDLRAD3,SMARCE1,GTF3C6,CNTN5,MLEC,METTL5,STX16,ZNF174,STOML2,ANKRD10,UTP20,BOLA3,PFDN4,OAZ2,DNAJC17,PML,QRSL1,FAM122A,RUVBL2,PDSS2,CCDC59 |
| 3.572e-04 | -7.94 | Spliceosome, U4/U6.U5 tri-snRNP | KEGG pathways | M00354 | 30 | 13 | 7161 | 1149 |
SART1,SNRNP200,LSM6,SNRPB,EFTUD2,LSM8,USP39,PRPF4,PRPF3,SNRPG,SNRPD3,TXNL4A,DDX23 |
| 3.572e-04 | -7.94 | Spliceosome, U4/U6.U5 tri-snRNP | KEGG pathways | hsa_M00354 | 30 | 13 | 7161 | 1149 |
SART1,SNRNP200,LSM6,SNRPB,EFTUD2,LSM8,USP39,PRPF4,PRPF3,SNRPG,SNRPD3,TXNL4A,DDX23 |
| 3.580e-04 | -7.93 | EIPR1 (EARP complex and GARP complex interacting protein 1) | protein interactions | 7260 | 69 | 23 | 17029 | 2761 |
CCDC93,CCT2,TRAPPC13,ETV3,CTCF,RCOR1,RAB6A,ARMH3,RAB1A,PSMD9,ZNF518A,RIC1,HMG20A,GIT2,OIP5,RAB18,SEC23IP,TMED10,GRIPAP1,SNAP29,RABGAP1L,EXOC4,MOB1A |
| 3.580e-04 | -7.93 | CCDC14 (coiled-coil domain containing 14) | protein interactions | 64770 | 69 | 23 | 17029 | 2761 |
FGFR1OP,UBQLN4,SKA3,MCM10,CCDC138,FOPNL,MAGED1,CNTROB,MAPK14,COMMD8,HAUS2,APP,SPAG5,HAUS8,PCM1,PEX5,CCP110,KIF14,CEP55,KIAA1328,CEP63,CCNB2,POC5 |
| 3.580e-04 | -7.93 | NUP214 (nucleoporin 214) | protein interactions | 8021 | 69 | 23 | 17029 | 2761 |
CSRP1,STRIP1,RAE1,CUL3,BRCA1,NDUFA7,UBE2I,KCMF1,TRIM28,LMNA,SMAD2,NUP107,NUP62,RPL19,NUP153,SMAD1,NUP85,NUP58,SMAD4,S100A6,IFI16,SEH1L,CFL1 |
| 3.581e-04 | -7.93 | GO_REGULATION_OF_INTRACELLULAR_PROTEIN_TRANSPORT | MSigDB lists | GO_REGULATION_OF_INTRACELLULAR_PROTEIN_TRANSPORT | 356 | 78 | 17377 | 2626 |
ZBED3,CYLD,TXN,CHERP,NF1,ZDHHC8,ANK3,STARD7,PLAGL2,PRKACA,MAPK14,PARK7,BCAP31,CDK5,MDM2,SP100,CDC42,PIK3R2,SRI,PARL,MAVS,CYB5R1,OGG1,HTRA2,PLK3,AKT2,GOPC,PSMB7,BRCA1,NUTF2,SOX4,EDEM2,TRIM28,USP36,TONSL,PSMD8,AXIN1,OGT,ZNF268,SMAD4,OAZ1,SVIP,DDX58,UBE2D3,RAB23,NUP54,CIB1,PPP3CB,HUWE1,AXIN2,FAM89B,PTPN11,GTSE1,MDFIC,ATG13,TGFB1,PPP3CA,GCC2,RHOA,KAT2A,ACSL3,RANGAP1,SH3GLB1,PRDX1,AKAP1,NUCB1,KEAP1,KPNA1,PCM1,CSK,OAZ2,PPP3R1,NUP62,PKD2,RUFY3,PARP10,FAF1,CDKN2A |
| 3.582e-04 | -7.93 | GCM_GSPT1 | MSigDB lists | GCM_GSPT1 | 155 | 40 | 17377 | 2626 |
WSB2,GORASP1,RBM8A,SNX15,ATG2B,BCL2L1,SLC35B2,FOXO3,ABHD16A,SAP130,NAPG,BRPF3,MTMR4,PPIG,PRDM4,CS,TNPO2,SS18L1,TARDBP,TTC17,CHTOP,LUC7L2,KDM3B,PHF10,ZNF84,BAZ2A,ZNF512,ATP2C1,CRNKL1,PRKRA,ZFAND5,CAND1,ANKRD10,HGS,VPS26B,SOCS4,MYO9A,BRD9,AAAS,B4GALT2 |
| 3.599e-04 | -7.93 | ribosome assembly | biological process | GO:0042255 | 60 | 20 | 17256 | 2622 |
PPAN,DDX28,RPS15,NOP2,WDR18,RPL6,RPS10,RPL38,EIF2A,EFL1,BRIX1,RPSA,RPL23A,RPL11,NIP7,RPS14,RPF2,RRS1,MRPL11,NSUN4 |
| 3.621e-04 | -7.92 | JI_RESPONSE_TO_FSH_DN | MSigDB lists | JI_RESPONSE_TO_FSH_DN | 56 | 19 | 17377 | 2626 |
ADD1,ZMYND11,RAF1,RRM2,TOP2B,PLEC,BRCA1,RAB6A,PITPNB,CCNF,MAT2A,KIF5B,GNS,RB1,JAK1,SNAP23,TFDP1,YWHAZ,PRPF4B |
| 3.621e-04 | -7.92 | TATCTGG,MIR-488 | MSigDB lists | TATCTGG,MIR-488 | 56 | 19 | 17377 | 2626 |
ZFP91,ACTR3,MIER1,SLC2A1,YTHDF3,TOPORS,CDK13,FANCI,CREM,ATP1A1,MLX,SIAH1,ZCCHC2,DCAF11,CAB39,YBX1,NCOA1,CHMP7,PDSS2 |
| 3.621e-04 | -7.92 | MORF_RAB11A | MSigDB lists | MORF_RAB11A | 56 | 19 | 17377 | 2626 |
DPM1,RAE1,TOR1AIP1,GMFB,NFATC2IP,PRPSAP1,RAB11A,PRPF18,TERF2IP,SMAD2,PDCD10,PARG,XPA,COX7A2L,TBPL1,PRPF4,DUSP11,WIPI2,COIL |
| 3.621e-04 | -7.92 | PID_P53_REGULATION_PATHWAY | MSigDB lists | PID_P53_REGULATION_PATHWAY | 56 | 19 | 17377 | 2626 |
USP7,CSNK1G2,CSNK1A1,MAPK14,TRIM28,RPL11,PPP2CA,CCNA2,MDM2,HUWE1,HIPK2,CSNK1G1,PIN1,CHEK2,YY1,CDK2,CSNK1D,CDKN2A,CSNK1G3 |
| 3.651e-04 | -7.92 | GO_TRANSCRIPTION_FROM_RNA_POLYMERASE_II_PROMOTER | MSigDB lists | GO_TRANSCRIPTION_FROM_RNA_POLYMERASE_II_PROMOTER | 696 | 138 | 17377 | 2626 |
RORB,CCNC,MAX,THOC1,PHRF1,RBM8A,SNRPD3,SNAPC4,PAPOLA,USF1,EIF4A3,GLIS2,ZNF639,INTS1,ETV6,SRSF4,TAF5L,TCEA1,ECD,MYBL1,ARID4A,DEAF1,GABPA,SNRPB,EAF2,SOX4,CBFB,PAF1,SMAD2,E2F4,BTF3,DVL1,ZNF45,SMAD1,ARRB2,E2F2,SSRP1,FUBP1,HIVEP3,POLR2K,ZNF768,CTCF,MEF2A,THRAP3,NOTCH2,PMF1,CDC73,SRRT,TFAP4,SUB1,NFATC3,MED8,MED10,INTS7,YBX1,MAML1,SRSF11,POLR2I,ELL2,LDB1,MYBL2,RTF1,SRSF5,ELK1,RXRB,POLR2J,RBMX,NFIL3,CEBPG,TBPL1,NRBP1,TCF12,MBD1,ASH1L,SARNP,FOXM1,PTTG1,PLAGL2,IRF3,NRF1,ZNF473,GMEB1,INTS12,RPAP1,TARDBP,CHTOP,ATF2,RPRD1B,DVL2,CSTF1,POU2AF1,POLR2L,POLR2G,POLR2D,RNPS1,E2F3,ELP4,SLBP,NFATC2,MEF2D,TRIM28,SUPT16H,SRSF1,TAF2,VEZF1,MAFK,ARNTL,SNRPG,AKNA,SMAD4,POU3F2,INTS2,CTDP1,CDC40,SRSF6,KLF13,ETS1,FOXO3,GTF2F1,WWP2,CCNK,IRF4,PRDM4,CREB1,STAT3,GTF2H2,RPRD1A,KAT2A,ZNF202,DDX39A,POLR2A,TFE3,PITX1,TAF12,SRSF3,RBPJ,TAF6,USF2 |
| 3.664e-04 | -7.91 | GAVIN_FOXP3_TARGETS_CLUSTER_T7 | MSigDB lists | GAVIN_FOXP3_TARGETS_CLUSTER_T7 | 92 | 27 | 17377 | 2626 |
CCT2,FTL,EIF3L,UGP2,GUK1,ANXA6,CAST,SNRPB,AMD1,UCK2,HNRNPF,CHCHD2,REEP5,RPS9,ECH1,EIF3H,TIMM13,JAK1,RPL32,SAR1A,PDRG1,QARS,STAT1,AKR1B1,MDH1,OAZ1,CDC37 |
| 3.673e-04 | -7.91 | ENK_UV_RESPONSE_EPIDERMIS_DN | MSigDB lists | ENK_UV_RESPONSE_EPIDERMIS_DN | 490 | 102 | 17377 | 2626 |
ZNF207,UBL3,HECA,TSC2,IVNS1ABP,UCK2,DHX8,SLC20A1,STAM,MXD1,GMEB1,FBXW2,RNF19A,TP53BP2,APOOL,TECR,F2R,PCBP2,RYBP,CDC5L,TIMP2,NXT1,PBXIP1,ERF,CIRBP,RNPS1,EZR,PFKFB3,PITPNB,CADM1,PSMB9,ODC1,STK17B,RAB22A,MAT2A,PPP2CA,PON2,CORO1C,EIF2D,ARNTL,SH3GLB2,ATF6,SCARB1,NCOA1,ZBTB11,RTN3,CBX4,SMNDC1,PDCD4,CSNK1D,HSPH1,NCOR2,PIGN,SH2D3A,DNAJB2,B4GALT5,CUTA,DBF4,VPS45,CHIC2,ASAH1,RACGAP1,DNAJB1,EPHX2,RLF,CRLF3,FAM8A1,TFRC,PNO1,NDUFS4,HOMER1,NFATC3,INPP5A,FJX1,PRC1,DCP1A,FEM1B,IMPA2,SPTAN1,PPAN,PPP3CA,CYTH1,TNFAIP3,GALC,ELL2,WDR1,GTPBP4,ITM2A,ARID1A,RHOB,DAPK3,PTPRF,SLCO4A1,KPNA4,GALNT2,SYNCRIP,UAP1,DCK,DBI,ACAT1,YWHAH,EGLN1 |
| 3.680e-04 | -7.91 | SUMOylation of RNA binding proteins | REACTOME pathways | R-HSA-4570464 | 48 | 18 | 10287 | 1696 |
NDC1,NUP188,RAE1,SUMO2,NUP54,NUP155,UBE2I,NUP205,PHC2,NUP210,NUP107,NUP153,NUP62,NUP85,NUP58,CBX4,SEH1L,AAAS |
| 3.707e-04 | -7.90 | DAZARD_RESPONSE_TO_UV_SCC_UP | MSigDB lists | DAZARD_RESPONSE_TO_UV_SCC_UP | 111 | 31 | 17377 | 2626 |
UBE2D3,CCNC,TMED7,RECQL,TSC22D3,RRM2,CTCF,ARHGDIB,CYB5A,SRSF1,SSR1,PAPOLA,KRR1,TAF2,FKBP1A,SCARB2,RAD51C,NAP1L1,SMAD2,RALB,PRDX3,PSMD8,SRI,YWHAZ,ACADM,PTGES3,CITED2,RBBP4,PDIA6,TOB1,SRSF10 |
| 3.708e-04 | -7.90 | GSE22601_DOUBLE_NEGATIVE_VS_DOUBLE_POSITIVE_THYMOCYTE_DN | MSigDB lists | GSE22601_DOUBLE_NEGATIVE_VS_DOUBLE_POSITIVE_THYMOCYTE_DN | 196 | 48 | 17377 | 2626 |
SRM,UBE2D3,BCCIP,HSPH1,PPP1R12A,GPBP1L1,CIB1,SIRT2,SLC35B1,DCUN1D4,ASXL2,SEC16A,FAM8A1,CAPN2,RAB21,INPP5A,MBD2,GLTP,UPF2,MAML1,CLTB,PDIA6,STAT3,ASB6,PPA1,PREB,PHF20L1,BAZ2A,COQ10B,IDH3A,NARF,TBRG4,FRAT2,FBXO9,EIF2AK1,ESYT1,AZI2,CYB5A,EIF3K,ALG3,RAB18,MFAP1,SNAP23,PITPNA,YWHAZ,ATF6,NMD3,SLC25A33 |
| 3.710e-04 | -7.90 | PCGF1 (polycomb group ring finger 1) | protein interactions | 84759 | 104 | 31 | 17029 | 2761 |
UBE2D3,USP7,TXN,SUZ12,TOR3A,USP42,LETMD1,DIDO1,PDCD7,PCGF1,ERC1,ARID1B,SRRT,TUBGCP2,PHC2,HSPA4,UPF1,NSF,SSBP3,PPP6C,PQBP1,NAA50,ATG13,CHMP4B,SASS6,PGAM1,CDK12,CCAR1,DDB1,RYBP,USP34 |
| 3.742e-04 | -7.89 | Mapk13 (mitogen-activated protein kinase 13) | protein interactions | 26415 | 82 | 26 | 17029 | 2761 |
CCT2,NASP,RPLP2,MDH2,DHX9,ILF3,LDHA,PKM,CCT8,EPRS,RPS14,YBX1,AHCY,YWHAZ,TAGLN2,FUS,NAP1L4,ATP5F1A,TFG,PDIA6,PGAM1,PABPC1,PPA1,EEF1D,NUDC,LDHB |
| 3.742e-04 | -7.89 | CPSF7 (cleavage and polyadenylation specific factor 7) | protein interactions | 79869 | 82 | 26 | 17029 | 2761 |
CCDC93,STAU1,EWSR1,SUZ12,RNPS1,DDX20,CSNK2A1,ATXN1,JMJD6,OGDH,PRMT2,MCM2,SEC16A,LUC7L,RPA1,WWP2,FAM192A,RPA2,SNRNP25,SMAD2,ERGIC3,KHSRP,GCC1,DVL2,SRPK2,CDC5L |
| 3.747e-04 | -7.89 | malignant_fibrous_histiocytoma-pleomorphic_sarcoma | COSMIC cancer mutations | malignant_fibrous_histiocytoma-pleomorphic_sarcoma | 36 | 14 | 17385 | 2587 |
KIF5B,RB1,EWSR1,NRAS,NF1,PTEN,SF3B1,ETV6,STK11,KRAS,FUS,SMAD4,HRAS,CDKN2A |
| 3.754e-04 | -7.89 | catalytic activity, acting on DNA | molecular function | GO:0140097 | 193 | 48 | 17224 | 2647 |
POLA2,RECQL,DNMT3A,TWNK,CHD1L,TATDN3,DHX9,TOP2B,BLM,CHD1,NEIL2,NEXMIF,MBD4,PCNA,XRCC2,CRY2,PTGES3,TOP1MT,DNMT1,OGG1,TERF2,GINS1,TDP1,ERCC1,PRIM2,POLK,HELB,TOP3A,PBRM1,DCLRE1C,MPG,POLG2,GINS4,RAD54B,XRCC5,RAD51C,POLE,CHD3,TATDN2,NEIL3,XRCC3,RUVBL2,RBPJ,TATDN1,GEN1,TERF1,RAD51D,POLQ |
| 3.758e-04 | -7.89 | FBXL7 (F-box and leucine rich repeat protein 7) | protein interactions | 23194 | 8 | 6 | 17029 | 2761 |
CUL1,ZRANB2,AHCYL1,BIRC5,APP,WDR48 |
| 3.758e-04 | -7.89 | TPH1 (tryptophan hydroxylase 1) | protein interactions | 7166 | 8 | 6 | 17029 | 2761 |
RFWD3,YWHAZ,MCM10,PRKACA,YWHAH,APP |
| 3.768e-04 | -7.88 | Nuclear import of Rev protein | REACTOME pathways | R-HSA-180746 | 33 | 14 | 10287 | 1696 |
NDC1,NUP188,NUP210,RAE1,NUP107,NUP54,NUP62,NUP153,NUP155,NUP85,NUP58,SEH1L,AAAS,NUP205 |
| 3.776e-04 | -7.88 | CALM1 (calmodulin 1) | protein interactions | 801 | 323 | 76 | 17029 | 2761 |
IMMT,CYLD,ADD1,TSC2,SF3B1,RAF1,RAC1,MYH9,CUL1,CSNK2A1,MAPK14,DST,CCNA2,RALB,UCHL5,DNAAF2,RAD23B,JOSD1,CLTB,CDC5L,LACTB,CUL3,AURKB,EDF1,MCM2,ANLN,LUC7L,FKBP3,OPTN,HSPA4,SEC61A1,BRWD1,CCDC14,RPS14,STK38,MYO18A,H2AFX,XRCC4,GCLM,UNK,EWSR1,MAPRE1,TCF3,DCTN2,STRN4,MYO9B,RGS2,DOCK11,PDCD7,MYL6B,PSMD2,C4orf3,CCP110,PTEN,HUWE1,PPIL2,DAPK1,YBX1,CAMK2G,GID8,FBXO9,KRAS,SRSF5,ADRB2,MATR3,SLTM,PRDX1,FAS,GNAS,MBIP,USP20,DDX5,CABIN1,ACADM,SLF2,ZBTB24 |
| 3.776e-04 | -7.88 | Golgi organization | biological process | GO:0007030 | 125 | 34 | 17256 | 2622 |
TMED7,GOLPH3L,GORASP1,VTI1A,TMED3,CSNK1A1,SEC16A,NPLOC4,UBXN2A,PDCD10,CDC42,VMP1,NSFL1C,LMAN1,TMED2,PLK3,GCC2,USO1,COG1,GORASP2,RAB1A,STX16,PI4K2A,OPTN,SEC23IP,GOLGA2,SURF4,TMED10,GOLGA8A,UBXN2B,MYO18A,VCPIP1,YWHAZ,CSNK1D |
| 3.776e-04 | -7.88 | regulation of type I interferon production | biological process | GO:0032479 | 125 | 34 | 17256 | 2622 |
DDX58,OTUD5,CYLD,POLR2K,DHX9,FLOT1,IRF3,POLR3K,NPLOC4,PIN1,MAVS,RNF135,RNF26,PCBP2,POLR2L,TNFAIP3,CGAS,PRKDC,POLR3GL,ISG15,IRF5,XRCC5,RPS27A,STAT6,STAT1,DTX4,NLRC5,PQBP1,CRCP,HMGB2,TICAM1,TRIM32,YY1,IFI16 |
| 3.782e-04 | -7.88 | GSE27670_CTRL_VS_LMP1_TRANSDUCED_GC_BCELL_UP | MSigDB lists | GSE27670_CTRL_VS_LMP1_TRANSDUCED_GC_BCELL_UP | 191 | 47 | 17377 | 2626 |
DNAJC2,PTMS,DNAJC5,SARNP,GPR132,MRPL39,RBM8A,TWF2,SPR,BIRC2,MXD1,RPA2,IRF4,FGFR3,SUB1,PRKD3,PSMA6,NEK6,ARPC5,TPST1,TIMELESS,CREB1,IMPA2,PRIM2,SELPLG,BTG2,MYBL2,KCTD20,EMP3,TOR1AIP2,AURKB,BRCA1,ESYT1,ASF1B,IRF5,GLOD4,NSA2,MTHFD2,HINT1,PML,TBPL1,COX8A,NUP62,BTF3,RAD51D,ADAM23,SMARCD1 |
| 3.782e-04 | -7.88 | GSE369_PRE_VS_POST_IL6_INJECTION_IFNG_WT_LIVER_DN | MSigDB lists | GSE369_PRE_VS_POST_IL6_INJECTION_IFNG_WT_LIVER_DN | 191 | 47 | 17377 | 2626 |
IER2,MIF4GD,NF1,CXXC1,CDK2AP2,HNRNPUL2,HEXB,SIKE1,RAP1A,ADD3,BRPF3,ARPC5,DPYSL2,METTL14,CRAT,TBC1D14,PRDM4,AP1M1,BRI3,TAGLN2,CDC25B,PIKFYVE,MAML1,CSNK1G3,ORAI2,SNX2,NEK7,TAOK1,EMP3,DNAJC9,RBM38,SH3BP5,AHNAK,JAK1,GPS2,DUSP3,PRDX5,NRM,PML,DMWD,MYO9A,ZNF830,EHD4,YWHAH,ABCA1,CAPN1,LRCH1 |
| 3.782e-04 | -7.88 | GSE37532_WT_VS_PPARG_KO_VISCERAL_ADIPOSE_TISSUE_TREG_DN | MSigDB lists | GSE37532_WT_VS_PPARG_KO_VISCERAL_ADIPOSE_TISSUE_TREG_DN | 191 | 47 | 17377 | 2626 |
USP7,TXN,DHPS,DNAJB2,RHOC,SDC2,HMGN3,AP3S1,CPNE3,RBM17,FKBP1A,GNS,PSMD2,CTNNBL1,ATP2A2,NOL11,SSBP3,RCSD1,RAB4A,CLDND1,ARL5A,TMED2,MED22,GTF3C6,LARS,CSRP1,TMEM39A,ELL2,CREG1,DENND4C,ANKRD33B,MAP4K4,PTTG1IP,NMT2,MID1IP1,SEC61A1,MAGT1,NSMCE2,ACLY,CHMP4B,YWHAZ,ANP32E,CLU,TSTD2,ABCA1,NUMB,GPATCH4 |
| 3.782e-04 | -7.88 | GSE22886_NAIVE_CD8_TCELL_VS_DC_DN | MSigDB lists | GSE22886_NAIVE_CD8_TCELL_VS_DC_DN | 191 | 47 | 17377 | 2626 |
WSB2,TBC1D12,NDUFV2,FEZ2,TXN,NQO1,RAC1,LAMTOR3,CSNK2A1,ZFYVE21,SLC4A2,MAN2B1,ATP6V1B2,PSEN1,ZNF804A,ATP6V0B,CTSS,DAPK1,H2AFY,ANXA5,TFG,SPTSSA,FTL,CYFIP1,SNX2,PPT1,LAP3,CREG1,KIAA0930,RCOR1,RIT1,CAPZA2,VDAC1,PI4K2A,CAT,HHEX,HSPA4,MTHFD2,SERF2,DUSP3,CORO1C,IMPDH1,MDH1,ZMIZ1,PGAM1,AP2S1,ATP6V0E1 |
| 3.782e-04 | -7.88 | GSE19772_HCMV_INFL_VS_HCMV_INF_MONOCYTES_AND_PI3K_INHIBITION_DN | MSigDB lists | GSE19772_HCMV_INFL_VS_HCMV_INF_MONOCYTES_AND_PI3K_INHIBITION_DN | 191 | 47 | 17377 | 2626 |
ANKH,CERK,KLC1,ASAH1,PPP3CB,DAZAP2,RGS2,MIEN1,LCLAT1,PCBP1,GOLM1,DECR1,RAB8A,GRSF1,SLC44A1,MSH2,EI24,PDS5B,MDFIC,CREB1,MINPP1,ARL5A,NUP85,SHOC2,CYFIP1,MAPRE2,EID1,PSPC1,NUDT4,EMB,RCOR1,DNAJC9,RHOT1,ODC1,TARS,CDCA4,HSPA4,AHNAK,RBM25,CDCA7L,OAZ2,U2SURP,DBI,NDE1,HEXA,CHPT1,TRAF5 |
| 3.786e-04 | -7.88 | histone-lysine N-methyltransferase activity | molecular function | GO:0018024 | 47 | 17 | 17224 | 2647 |
ASH1L,KMT2E,SUZ12,CXXC1,EHMT1,NSD3,WDR82,EZH1,MEN1,KMT2C,WDR5,DOT1L,SUV39H2,KMT5C,SETD3,KMT5A,KMT2B |
| 3.788e-04 | -7.88 | leukocyte activation | biological process | GO:0045321 | 879 | 170 | 17256 | 2622 |
ADA2,RAB14,KMT2E,ADAM10,HEXB,NHLRC3,GYG1,MAPK14,KCMF1,CMTM6,PA2G4,RAP1A,PSMD1,TXLNA,AP1M1,PLCL2,KCNAB2,BAK1,SP3,ERCC1,EXOSC6,NRAS,NCK1,ARHGAP45,CYSTM1,SOX4,CBFB,RAB5B,STOML2,HHEX,WAS,AGPAT2,ITGB1,CAB39,ADAM9,STK11,ATP6V0C,ROCK1,CLU,CAPN1,SVIP,DNAJC5,GMFG,HLA-E,LAMTOR3,B4GALT1,ASAH1,CDK13,MAN2B1,NOTCH2,EIF2AK4,PPP3CB,RAB6A,DOCK11,PSEN1,TMEM179B,GNS,CD59,FKBP1A,ARPC5,KIF13B,CTPS1,MSH2,BCL2,OSTF1,MVP,LPCAT1,KDELR1,CYFIP1,FTL,CREG1,MFNG,ITM2A,C1orf35,PKM,ARMC8,CCT8,PI4K2A,CAND1,XRCC5,CAT,TSC1,SNAP23,ACLY,CEBPG,CTSA,GPI,RHOG,KARS,SNX27,CYLD,DYNLL1,RAC1,MYH9,NIT2,LYN,CPNE3,VAV1,BRI3,CORO1A,TMBIM1,GM2A,CPNE1,ENPP4,CCT2,TIMP2,SELPLG,RAB7A,PPIE,PSMB7,ATP6V0A1,LRRC8A,DCLRE1C,CADM1,AZI2,TOLLIP,ALDH3B1,DSN1,SURF4,DDOST,RAB24,PSMD3,STAT6,CANT1,TICAM1,PDXK,LTA4H,MAPK1,TUBB,MIF,MANBA,PDAP1,TCF3,BTN3A1,JMJD6,IL21R,DNAJB9,PTPN2,PSMD2,IRF4,CTSS,HUWE1,CNN2,STAT3,MSH6,SPTAN1,TGFB1,PPP3CA,ADAM17,RHOA,MLEC,PRKDC,HEBP2,KLF6,FADD,NEU1,PRDX1,HSPA1B,RAB18,ATP6V1D,MAGT1,GOLGA7,GPS2,SNAP29,PGRMC1,IMPDH1,RBPJ,PSAP,PGAM1,IGBP1 |
| 3.801e-04 | -7.88 | early endosome | cellular component | GO:0005769 | 341 | 74 | 18223 | 2701 |
MIB2,WASF2,CCDC93,RAB14,SNX27,CYTIP,ANKRD27,PTP4A3,NIPA2,RUFY1,STAM,KIFC1,RAB21,RAP1A,SIAH1,MTMR4,RABGAP1L,RAB4A,CORO1A,F2R,SNX8,CLCN3,AKT2,RAB1A,RAB5B,RAB22A,PLEKHF2,VPS26B,GRIPAP1,VIPAS39,VPS4A,CLN3,MAPK1,NUMB,TM9SF4,GGA1,HLA-E,TRAK1,FLOT1,GGA2,TMEM165,HLA-A,TFRC,PIKFYVE,ST8SIA2,ATP6V0D1,MYO5A,SNX2,USP10,KCNQ1,ADRB2,WDR81,APPL1,MAP2K2,PICALM,RHOB,PI4K2A,MAPK3,DERL1,HLA-B,TMEM127,NUCB1,HGS,PRDX3,APPL2,PML,SIAH2,WDR91,EHD4,RPS6KC1,ECPAS,VPS29,NIPA1,ALS2 |
| 3.804e-04 | -7.87 | skin-back-benign_melanocytic_nevus-Spitz | COSMIC cancer mutations | skin-back-benign_melanocytic_nevus-Spitz | 21 | 10 | 17385 | 2587 |
KIF5B,PWWP2A,NRAS,ZCCHC8,HRAS,ERC1,HLA-A,MYO5A,LMNA,DCTN1 |
| 3.804e-04 | -7.87 | skin-buttock-benign_melanocytic_nevus-Spitz | COSMIC cancer mutations | skin-buttock-benign_melanocytic_nevus-Spitz | 21 | 10 | 17385 | 2587 |
KIF5B,PWWP2A,NRAS,ZCCHC8,HRAS,ERC1,HLA-A,MYO5A,LMNA,DCTN1 |
| 3.804e-04 | -7.87 | skin-chest-benign_melanocytic_nevus-Spitz | COSMIC cancer mutations | skin-chest-benign_melanocytic_nevus-Spitz | 21 | 10 | 17385 | 2587 |
KIF5B,PWWP2A,NRAS,ZCCHC8,HRAS,ERC1,HLA-A,MYO5A,LMNA,DCTN1 |
| 3.804e-04 | -7.87 | skin-upper_leg-benign_melanocytic_nevus-Spitz | COSMIC cancer mutations | skin-upper_leg-benign_melanocytic_nevus-Spitz | 21 | 10 | 17385 | 2587 |
KIF5B,PWWP2A,NRAS,ZCCHC8,HRAS,ERC1,HLA-A,MYO5A,LMNA,DCTN1 |
| 3.804e-04 | -7.87 | skin-leg-benign_melanocytic_nevus-Spitz | COSMIC cancer mutations | skin-leg-benign_melanocytic_nevus-Spitz | 21 | 10 | 17385 | 2587 |
KIF5B,PWWP2A,NRAS,ZCCHC8,HRAS,ERC1,HLA-A,MYO5A,LMNA,DCTN1 |
| 3.804e-04 | -7.87 | skin-foot-benign_melanocytic_nevus-Spitz | COSMIC cancer mutations | skin-foot-benign_melanocytic_nevus-Spitz | 21 | 10 | 17385 | 2587 |
KIF5B,PWWP2A,NRAS,ZCCHC8,HRAS,ERC1,HLA-A,MYO5A,LMNA,DCTN1 |
| 3.804e-04 | -7.87 | skin-shoulder-benign_melanocytic_nevus-Spitz | COSMIC cancer mutations | skin-shoulder-benign_melanocytic_nevus-Spitz | 21 | 10 | 17385 | 2587 |
KIF5B,PWWP2A,NRAS,ZCCHC8,HRAS,ERC1,HLA-A,MYO5A,LMNA,DCTN1 |
| 3.805e-04 | -7.87 | RICKMAN_METASTASIS_DN | MSigDB lists | RICKMAN_METASTASIS_DN | 238 | 56 | 17377 | 2626 |
RHOG,TXN,ACTR3,SLC2A1,CCM2,TAP1,KLF13,PCSK7,BCL2L1,ARF1,ATP6V1B2,LMNA,DST,FARSA,VASP,TNFAIP8,ARPC5,TBC1D22A,RBM34,DDA1,DNM2,TNPO2,TAP2,OSTF1,TAGLN2,S100A6,CARM1,MORC3,ADCY7,BAK1,RHOA,TRAFD1,GUK1,LRRC8A,MIER2,ARHGEF12,BICD2,MEF2D,OGDH,PSMB9,MAP2K2,DAPK3,TFEB,SLC19A1,KEAP1,PDLIM1,CLK3,CORO1C,PML,NLRC5,SH3GLB2,ASNA1,CENPT,PGAM1,HRAS,IFI16 |
| 3.807e-04 | -7.87 | intrinsic apoptotic signaling pathway in response to DNA damage | biological process | GO:0008630 | 69 | 22 | 17256 | 2622 |
BAK1,PGAP2,PRKDC,TMEM109,CDIP1,MCL1,TOPORS,BCL2L1,BRCA1,MOAP1,HIPK2,XPA,E2F1,PML,MSH2,AEN,FNIP2,BCL2,CHEK2,MSH6,IFI16,HTRA2 |
| 3.823e-04 | -7.87 | haematopoietic_and_lymphoid_tissue-liver-lymphoid_neoplasm-Burkitt_lymphoma | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-liver-lymphoid_neoplasm-Burkitt_lymphoma | 6 | 5 | 17385 | 2587 |
RB1,KRAS,NRAS,SF3B1,HRAS |
| 3.823e-04 | -7.87 | skin-arm-malignant_melanoma-superficial_spreading | COSMIC cancer mutations | skin-arm-malignant_melanoma-superficial_spreading | 6 | 5 | 17385 | 2587 |
KRAS,NRAS,PTEN,HRAS,CDKN2A |
| 3.823e-04 | -7.87 | skin-hand-malignant_melanoma-superficial_spreading | COSMIC cancer mutations | skin-hand-malignant_melanoma-superficial_spreading | 6 | 5 | 17385 | 2587 |
KRAS,NRAS,PTEN,HRAS,CDKN2A |
| 3.823e-04 | -7.87 | haematopoietic_and_lymphoid_tissue-lymph_node-lymphoid_neoplasm-lymphoplasmacytic_lymphoma | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-lymph_node-lymphoid_neoplasm-lymphoplasmacytic_lymphoma | 6 | 5 | 17385 | 2587 |
KRAS,NRAS,PTEN,HRAS,CDKN2A |
| 3.823e-04 | -7.87 | skin-foot-malignant_melanoma-superficial_spreading | COSMIC cancer mutations | skin-foot-malignant_melanoma-superficial_spreading | 6 | 5 | 17385 | 2587 |
KRAS,NRAS,PTEN,HRAS,CDKN2A |
| 3.823e-04 | -7.87 | skin-trunk-malignant_melanoma-superficial_spreading | COSMIC cancer mutations | skin-trunk-malignant_melanoma-superficial_spreading | 6 | 5 | 17385 | 2587 |
KRAS,NRAS,PTEN,HRAS,CDKN2A |
| 3.823e-04 | -7.87 | skin-in_situ_epithelial_neoplasm-actinic_keratosis | COSMIC cancer mutations | skin-in_situ_epithelial_neoplasm-actinic_keratosis | 6 | 5 | 17385 | 2587 |
FGFR3,KRAS,NRAS,HRAS,CDKN2A |
| 3.823e-04 | -7.87 | haematopoietic_and_lymphoid_tissue-salivary_gland-lymphoid_neoplasm-diffuse_large_B_cell_lymphoma | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-salivary_gland-lymphoid_neoplasm-diffuse_large_B_cell_lymphoma | 6 | 5 | 17385 | 2587 |
RB1,KRAS,NRAS,STAT3,HRAS |
| 3.824e-04 | -7.87 | TPRKB (TP53RK binding protein) | protein interactions | 51002 | 41 | 16 | 17029 | 2761 |
RPA2,METTL1,COMMD10,MBIP,TPD52L2,TP53RK,HSPBP1,GORASP1,LAP3,ARPC5,ACTR3,LAGE3,RANGAP1,AGFG1,ARPC1A,SH3GLB1 |
| 3.824e-04 | -7.87 | ACAT2 (acetyl-CoA acetyltransferase 2) | protein interactions | 39 | 41 | 16 | 17029 | 2761 |
UBXN1,OLA1,CSNK2A1,PKM,SPR,PCBP1,VASP,PFDN4,ACAT1,AHCY,HEXA,PABPC1,TERF1,PCBP2,ALDH9A1,MLST8 |
| 3.824e-04 | -7.87 | SUCLG2 (succinate-CoA ligase GDP-forming beta subunit) | protein interactions | 8801 | 41 | 16 | 17029 | 2761 |
MRPL50,RPN1,NDUFV2,SEPT9,SUCLG1,IDH3A,MRPL12,CUL3,LDHA,ACADM,DMWD,OGDH,PEF1,PITRM1,SDHA,ZNF146 |
| 3.824e-04 | -7.87 | IGF2R (insulin like growth factor 2 receptor) | protein interactions | 3482 | 41 | 16 | 17029 | 2761 |
EWSR1,TM9SF4,CREG1,GGA1,TMEM216,ATXN1,CSNK2A1,PACS1,GGA2,COA7,NCDN,XRCC5,USF1,GTSE1,CHMP4B,USF2 |
| 3.843e-04 | -7.86 | Progesterone-mediated oocyte maturation | KEGG pathways | hsa04914 | 92 | 28 | 7161 | 1149 |
PLK1,RAF1,RPS6KA1,AKT2,KRAS,ANAPC2,PKMYT1,CDC23,CCNB1,MAPK14,PDE3B,PRKACA,MAD2L2,MAPK3,CCNA2,CDC16,CDC27,PIK3R2,ADCY9,ANAPC7,CDC25B,MAPK1,CCNB2,CDK2,GNAI2,CPEB2,ANAPC4,ADCY7 |
| 3.843e-04 | -7.86 | Progesterone-mediated oocyte maturation | KEGG pathways | ko04914 | 92 | 28 | 7161 | 1149 |
PLK1,RAF1,RPS6KA1,AKT2,KRAS,ANAPC2,PKMYT1,CDC23,CCNB1,MAPK14,PDE3B,PRKACA,MAD2L2,MAPK3,CCNA2,CDC16,CDC27,PIK3R2,ADCY9,ANAPC7,CDC25B,MAPK1,CCNB2,CDK2,GNAI2,CPEB2,ANAPC4,ADCY7 |
| 3.850e-04 | -7.86 | GSE39820_CTRL_VS_TGFBETA1_IL6_IL23A_CD4_TCELL_UP | MSigDB lists | GSE39820_CTRL_VS_TGFBETA1_IL6_IL23A_CD4_TCELL_UP | 186 | 46 | 17377 | 2626 |
PWWP2A,HSPH1,ASH1L,FAM208B,C1orf112,PPP1R15B,XIAP,PRPF39,FAM8A1,TFRC,RPA2,AHCTF1,WDR44,ZCCHC2,PHF14,PTPN11,ZFYVE27,FEM1B,ACAD8,CREB1,CNOT6L,RBM15,C12orf75,ZNF770,MORC3,TTPAL,GABPA,DENND1B,TEX10,ZMYM5,TUBGCP5,WIPF1,CBFB,STX16,BORA,MAT2A,HSPA1B,SERTAD2,ELMO1,LUC7L3,PRPS2,ITGB1,NAA20,PTDSS1,FAF1,ESYT2 |
| 3.850e-04 | -7.86 | GSE12198_LOW_IL2_STIM_NK_CELL_VS_HIGH_IL2_STIM_NK_CELL_UP | MSigDB lists | GSE12198_LOW_IL2_STIM_NK_CELL_VS_HIGH_IL2_STIM_NK_CELL_UP | 186 | 46 | 17377 | 2626 |
NCOR2,TMUB1,RAB11B,OLA1,CHIC2,PTP4A3,GGA2,PARN,BZW2,SAC3D1,PSMD2,C18orf32,LPIN2,MECR,FOXN2,MRPL54,AHCYL1,MTX2,ASB6,ZC3H3,CDC5L,VOPP1,KDM3B,EIF3L,MAPRE2,DRAP1,BTG2,PSMB7,TBRG4,ITM2A,FAM133B,BMS1,BUD13,MBD3,FOXRED1,SEC31A,MAP3K4,ALG3,PCM1,SMAD2,UPF1,ATP1A1,FBXO28,GADD45B,CSNK1D,GEMIN7 |
| 3.850e-04 | -7.86 | GSE41867_NAIVE_VS_DAY8_LCMV_CLONE13_EFFECTOR_CD8_TCELL_UP | MSigDB lists | GSE41867_NAIVE_VS_DAY8_LCMV_CLONE13_EFFECTOR_CD8_TCELL_UP | 186 | 46 | 17377 | 2626 |
NAT14,FGFR1OP,CMAS,SMAP1,WDYHV1,UBR2,CCM2,SLC39A13,MYH9,CHIC2,TMED3,NCAPG,STMN1,MXD1,FERMT3,RAP1A,ARHGEF1,XPA,ABCD1,NDUFS8,TAP2,OSTC,ZNF710,RNF169,CSNK1G3,ANKLE2,NIPAL3,ABHD2,TK1,PSRC1,PTPN18,ELL2,RB1CC1,ASPM,ARID1A,ARSK,GALNT2,RBM47,CERS6,ATP6V0C,SLAIN1,GPI,USP11,IGBP1,SNX14,TMEM131 |
| 3.850e-04 | -7.86 | GSE17186_NAIVE_VS_CD21HIGH_TRANSITIONAL_BCELL_CORD_BLOOD_UP | MSigDB lists | GSE17186_NAIVE_VS_CD21HIGH_TRANSITIONAL_BCELL_CORD_BLOOD_UP | 186 | 46 | 17377 | 2626 |
MIF,TCF12,NADSYN1,SYS1,ADD1,TOR3A,TCF3,UROD,SLC2A1,AKT1S1,EZH1,ZADH2,LYRM2,KTN1,MAT2B,MRPL50,RRN3,PSMA6,INTS7,HDAC7,DAD1,PPME1,POP7,HADHB,PDCD2,NCK1,AACS,LNX2,DNAJC9,POLR3GL,FBXO9,ESYT1,ICAM2,KRTCAP2,NEU1,TWISTNB,SDHB,POLR2J,JAK1,SNAP29,ARNTL,PQBP1,PRMT7,SLC25A19,PSMC1,TIGD2 |
| 3.850e-04 | -7.86 | GSE37532_TREG_VS_TCONV_PPARG_KO_CD4_TCELL_FROM_VISCERAL_ADIPOSE_TISSUE_DN | MSigDB lists | GSE37532_TREG_VS_TCONV_PPARG_KO_CD4_TCELL_FROM_VISCERAL_ADIPOSE_TISSUE_DN | 186 | 46 | 17377 | 2626 |
DDX58,CYTIP,CDS2,TRIO,HEXB,XIAP,AP3M2,MON1B,MED13L,CTCF,CHKB,CCNL2,GGA2,DAZAP2,RGS2,DUSP22,CRLF3,ETS1,MBD4,HERC3,ADD3,CWC27,RABGAP1L,MBD2,LPIN2,HP1BP3,ADCY7,TTPAL,TSPYL4,EAF2,KLF6,STK17B,SH3GLB1,DDX17,FAS,KRIT1,SCARB2,TRAM2,TXNDC16,BRWD1,HPS5,KBTBD7,CEBPG,CENPT,BRD9,ABCA1 |
| 3.886e-04 | -7.85 | MPHOSPH8 (M-phase phosphoprotein 8) | protein interactions | 54737 | 61 | 21 | 17029 | 2761 |
ANKLE2,DDX28,FAM208B,DNMT3A,MPHOSPH8,NOP2,CGAS,EHMT1,ILF3,SAFB2,ZNF121,MATR3,RPL36,UBTF,FBXL6,SAFB,FAM208A,ZNF770,IFI16,ESYT2,TMEM33 |
| 3.886e-04 | -7.85 | MRPL24 (mitochondrial ribosomal protein L24) | protein interactions | 79590 | 61 | 21 | 17029 | 2761 |
RPS15,MRPL9,MRPL42,MRPL39,RPL6,TUFM,RPL8,CUL3,MRPS10,RBM4,MRPL19,APP,RPL11,MRPL50,MRPL2,RPL17,GRSF1,DUSP11,MRPL40,MRPL21,MRPL13 |
| 3.889e-04 | -7.85 | GO_POSITIVE_REGULATION_OF_CELLULAR_PROTEIN_LOCALIZATION | MSigDB lists | GO_POSITIVE_REGULATION_OF_CELLULAR_PROTEIN_LOCALIZATION | 335 | 74 | 17377 | 2626 |
ZBED3,RHOG,CHERP,ZDHHC8,DYNLL1,ANK3,STARD7,PLAGL2,SIRT2,CCNB1,BECN1,MAPK14,PRKACA,PARK7,BCAP31,CDK5,MDM2,CDC42,PIK3R2,MAVS,CYB5R1,TP53BP2,GPD1L,HTRA2,PLK3,PLK1,CCT2,TRIM8,AKT2,KAT7,PSMB7,EZR,BRCA1,NUTF2,EDEM2,TRIM28,USP36,PSMD8,ITGB1,OGT,STK11,ZNF268,OAZ1,SMAD4,UBE2D3,DDX58,CIB1,NKD2,PPP3CB,KIF5B,HUWE1,GTSE1,BCL2,ATG13,HNRNPM,TGFB1,PDPK1,PPP3CA,RHOA,KAT2A,ACSL3,CCT8,SH3GLB1,KPNA1,PCM1,OAZ2,TFDP1,E2F1,PML,PPP3R1,YWHAZ,RUFY3,YWHAH,CDKN2A |
| 3.892e-04 | -7.85 | GO_MULTI_ORGANISM_TRANSPORT | MSigDB lists | GO_MULTI_ORGANISM_TRANSPORT | 65 | 21 | 17377 | 2626 |
NUP188,THOC1,RAE1,TAP1,NUP54,NUP155,NUP205,NMT2,DERL1,KPNA4,KPNA1,NUP210,RPS27A,NUP107,NUP62,NUP153,TAP2,KPNA2,NUP85,AAAS,SEH1L |
| 3.892e-04 | -7.85 | GCM_HBP1 | MSigDB lists | GCM_HBP1 | 65 | 21 | 17377 | 2626 |
SNRNP200,ZCCHC8,OLA1,LAMTOR3,YTHDF3,ARID1A,PRKRA,ZFAND5,TARS,SAP130,RRN3,RBM25,TAB2,HNRNPR,HNRNPH3,RNASEK,BTF3L4,TARDBP,COPS6,CHTOP,LUC7L2 |
| 3.892e-04 | -7.85 | GATGKMRGCG_UNKNOWN | MSigDB lists | GATGKMRGCG_UNKNOWN | 65 | 21 | 17377 | 2626 |
REPS2,STRN4,E2F3,TIA1,ZADH2,RAB22A,CNOT3,RAD23A,UBTF,TSC1,SUV39H2,ZNRF2,HPS5,ZBTB22,RBM3,NFU1,H3F3A,EIF5,RNF26,YY1,MED22 |
| 3.892e-04 | -7.85 | GO_MULTI_ORGANISM_LOCALIZATION | MSigDB lists | GO_MULTI_ORGANISM_LOCALIZATION | 65 | 21 | 17377 | 2626 |
NUP188,THOC1,RAE1,TAP1,NUP54,NUP155,NUP205,NMT2,DERL1,KPNA4,KPNA1,NUP210,RPS27A,NUP107,NUP62,KPNA2,TAP2,NUP153,NUP85,SEH1L,AAAS |
| 3.914e-04 | -7.85 | GSE3982_MAST_CELL_VS_MAC_DN | MSigDB lists | GSE3982_MAST_CELL_VS_MAC_DN | 181 | 45 | 17377 | 2626 |
HIVEP3,PTMS,RAC1,CREBL2,SIRT2,MAN2B1,BCL2L1,NANS,GGA2,FOXO3,ZNF804A,CTSS,PSMA6,MCM5,AP2B1,RP2,CLPTM1,SRSF11,RPP25,NAGPA,CYFIP1,ACP2,MKLN1,PPT1,SLBP,CAPZA2,EML4,RHEB,GINS4,OPTN,KIF2A,INF2,ATP1A1,NSF,RBL1,ACOX1,STAT1,ADAM9,IMPDH1,ZDHHC7,FKBP5,KPNA2,PDXK,HEXA,DDX52 |
| 3.914e-04 | -7.85 | GO_PROTEIN_DEPHOSPHORYLATION | MSigDB lists | GO_PROTEIN_DEPHOSPHORYLATION | 181 | 45 | 17377 | 2626 |
CTDP1,PPP1R12A,EYA1,PPP1R15B,PTP4A3,CYCS,PPP3CB,DUSP22,EPM2A,UBLCP1,PTPN2,PPP1R3B,PDXP,PTEN,MTMR4,PPP4R1,PPP6C,PTPN11,BCL2,CDC25B,RPRD1B,CTDSP2,ILKAP,CAMK2G,TIMM50,PTPRK,PPP3CA,PTPN18,RPRD1A,ACP2,NCK1,MTMR6,STYXL1,PTPRF,MTMR3,PPP2CA,DUSP3,PPM1G,PPA2,PTPN7,PPP3R1,DUSP11,PTPDC1,PPP5C,EYA2 |
| 3.914e-04 | -7.85 | GSE37532_TREG_VS_TCONV_PPARG_KO_CD4_TCELL_FROM_LN_DN | MSigDB lists | GSE37532_TREG_VS_TCONV_PPARG_KO_CD4_TCELL_FROM_LN_DN | 181 | 45 | 17377 | 2626 |
RHOG,HIVEP3,IER2,KARS,SCAMP3,RRP15,RPS6KA1,TAP1,NIT2,PNO1,TET3,LYAR,ZNHIT6,TXLNA,RPF2,ZNF226,EIF5,PDIA6,STAT3,PPAN,TGFB1,METTL1,GTF3C6,NXT1,MIOS,TSPAN31,BTG2,TYW1,MRPL12,DCUN1D5,GALNT7,GAR1,EIF3G,USP36,YIF1A,ZNF317,DAP3,TIMM13,RBM25,CCDC86,CERS6,NCLN,RRS1,ATP6V0E1,SSSCA1 |
| 3.914e-04 | -7.85 | GSE22886_IGM_MEMORY_BCELL_VS_BM_PLASMA_CELL_UP | MSigDB lists | GSE22886_IGM_MEMORY_BCELL_VS_BM_PLASMA_CELL_UP | 181 | 45 | 17377 | 2626 |
CDC40,RPS2,PPP1R12A,MANBA,ANKH,TIA1,NOTCH2,ZNF267,SNN,GGA2,ATP6V1B2,PPP1R16B,SYNRG,APP,RPL11,RPL23A,MAT2B,RPA2,ADD3,TNFAIP8,RPL17,RBM34,CORO1A,CFL1,MORC3,PTPRK,NIPSNAP1,ELOVL5,MAPRE2,RFC3,PTPN18,NASP,PSPC1,ARHGDIB,SRSF5,ESYT1,SEPT7,SF3A2,ARHGAP15,RPSA,SUPT16H,CAT,DCK,STAT6,QRSL1 |
| 3.914e-04 | -7.85 | GSE45365_HEALTHY_VS_MCMV_INFECTION_CD8A_DC_IFNAR_KO_UP | MSigDB lists | GSE45365_HEALTHY_VS_MCMV_INFECTION_CD8A_DC_IFNAR_KO_UP | 181 | 45 | 17377 | 2626 |
SCAMP3,RPS6KA1,MANBA,UCK2,NKRF,HAUS4,TMED3,LANCL1,BLM,GGA2,MAPK14,PARN,RSAD1,RPL11,PCYOX1L,AHCTF1,ATIC,MRPL34,PIGG,ANP32A,OSTF1,KNTC1,MRPL48,ACAD8,LYPLA2,PGAP2,EIF3L,POLR2I,TRAFD1,TRAPPC9,ICMT,PDE3B,USP21,MAP2K2,SERP1,RPSA,CLNS1A,PRIM1,CAT,RPL37,ZNF862,QARS,FASTK,AXIN1,DMWD |
| 3.917e-04 | -7.85 | endosome | cellular component | GO:0005768 | 883 | 167 | 18223 | 2701 |
MIB2,CCDC93,RAB14,PTP4A3,TGOLN2,BECN1,RUFY1,KIFC1,RAB8A,RAP1A,RAB35,RABGAP1L,RAB4A,DNM2,ZFYVE27,AP2B1,MARCH2,CARMIL1,ATG9A,AKT2,EZR,RAB5B,RAB22A,PLEKHF2,OPTN,TBC1D17,RPS27A,GRIPAP1,ITGB1,VIPAS39,ATP6V0C,VPS4A,CLN3,ARRB2,ATP6V0E1,NUMB,STARD3NL,UBE2D3,TBC1D12,TMUB1,SCOC,GGA1,TM9SF4,CCZ1,HLA-E,CDIP1,RAB23,LAMTOR3,ACAP1,TMEM165,VPS25,WDR48,SLC31A1,ARPC5,SNX18,ZNRF2,ATP6V0A2,PIKFYVE,ATP6V0D1,VOPP1,USP10,ADRB2,APPL1,MAP2K2,RHOB,RMC1,PI4K2A,DERL1,SCARB2,OSBPL11,LAMTOR4,SIAH2,APPL2,EHD4,CDK2,ECPAS,SNX14,ALS2,NIPA1,WASF2,CHMP2A,ANKRD27,CYTIP,SNX27,GNPNAT1,RAB11B,RAC1,VTI1A,MON1B,ZFYVE21,RRAGC,NIPA2,STAM,APP,CD320,CRKL,ATP6V0B,RAB21,SIAH1,WDR44,MTMR4,TBC1D14,CLCN6,CDKN1B,CORO1A,F2R,TMEM9,TMBIM1,SNX8,SNX25,CLCN3,RAB7A,ATP6V0A1,CHMP2B,RAB1A,AP4E1,ATP1A1,CHMP4A,VPS26C,JAK1,VPS26B,TAB2,RAB24,CHMP4B,TICAM1,MAPK1,AP2S1,CHID1,DYNC1LI2,GOLIM4,ANKRD13D,ANXA6,FLOT1,VPS45,TRAK1,GGA2,IFT27,RAB11A,SCYL2,TFRC,HLA-A,PIP5K1C,SPPL2A,CTSS,ST8SIA2,TPCN1,MYO5A,RHOA,SNX2,RFFL,KCNQ1,WDR81,PICALM,SPPL2B,MAPK3,CTSL,HLA-B,TMEM127,NUCB1,HGS,PDCD6,PRDX3,PML,WDR91,RPS6KC1,CHMP7,VPS29 |
| 3.922e-04 | -7.84 | SEC16A (SEC16 homolog A, endoplasmic reticulum export factor) | protein interactions | 9919 | 141 | 39 | 17029 | 2761 |
NCOR2,MAPRE1,HNRNPUL2,MYH9,XPNPEP3,CSNK1A1,RBM4,ANKRD28,SHC1,ZKSCAN1,CENPJ,SEC24C,GTSE1,CRY2,CLTB,ANKHD1,HNRNPM,TERF2,DCTN1,USO1,ERF,CUL3,CAPZA2,BRCA1,MCM2,PICALM,FKBP3,CAND1,EIF4ENIF1,AHNAK,CDKN2AIPNL,GOLGA2,HNRNPH3,MYO18A,FAM83D,IMPDH1,CDK2,TERF1,EYA2 |
| 3.924e-04 | -7.84 | V$NFY_C | MSigDB lists | V$NFY_C | 233 | 55 | 17377 | 2626 |
WASF2,PRPF38B,ZBTB10,SUZ12,ZFP91,CDK2AP2,TRMT6,AP3M2,ENSA,STARD7,KIF23,RACGAP1,IFT27,LCLAT1,RBM4,MIS12,ARL6IP6,MCTS1,MRPL50,RPA2,SSBP3,FUT8,ARL6IP1,RPN2,NDUFS8,FAM76B,TECR,GNAI2,OGG1,ZNF189,FDFT1,MLEC,KAT7,HELB,WBP2,WDR81,MTX1,USP21,ARL17A,SNRPA,PI4K2A,C19orf54,TMEM184C,CAT,SMAD2,ACYP1,ELMO1,TPP2,SEL1L,DCAF11,ZNF436,H3F3A,UBE2C,LRP8,ESPL1 |
| 3.932e-04 | -7.84 | GCM_MSN | MSigDB lists | GCM_MSN | 28 | 12 | 17377 | 2626 |
HMGN1,MAPRE1,RHOA,DRAP1,ARHGEF1,DHX9,DDX5,YWHAZ,ARHGDIB,PTGES3,PCBP1,ABCC1 |
| 3.935e-04 | -7.84 | ribonucleoside binding | molecular function | GO:0032549 | 373 | 82 | 17224 | 2647 |
RHOG,RAB14,RAB11B,RAC1,OLA1,TPX2,RRAGC,GLUD1,EFL1,MIEF1,RAB21,RAB8A,RAP1A,CDC42,SAR1A,RALB,RAB35,RAB4A,DNM2,UPRT,SEPT11,SUCLG2,RP2,EIF5,ARL5A,RHOBTB3,NRAS,SEPT9,CGAS,RAB7A,RAB1A,ARL5B,RAB5B,RAB22A,LSG1,RAB2B,ARF4,RHEB,DAP3,SEPT1,RAB24,GUCY1B1,TUBB,RHEBL1,ANXA6,RHOC,GSPT2,RAB23,ARFIP2,RAB6A,ARF1,IFT27,RAB11A,GFM2,RTKN,GTPBP3,ARF5,EFTUD2,DAPK1,POLR1B,GNAI2,RHOA,NOA1,TUFM,GTPBP4,SEPT8,BMS1,KRAS,RIT1,RHOT1,SEPT7,RHOT2,GUF1,RHOB,MFN2,GNAS,ADSS,GNA12,RAB18,PRPS2,EHD4,HRAS |
| 3.953e-04 | -7.84 | REACTOME_UNFOLDED_PROTEIN_RESPONSE | MSigDB lists | REACTOME_UNFOLDED_PROTEIN_RESPONSE | 74 | 23 | 17377 | 2626 |
EXOSC6,ADD1,CXXC1,EXOSC9,SYVN1,PARN,SERP1,LMNA,DNAJB9,SSR1,YIF1A,SEC31A,EXOSC7,SHC1,TATDN2,EXOSC1,KHSRP,ATF6,PDIA6,CTDSP2,ATP6V0D1,PREB,DCTN1 |
| 3.955e-04 | -7.84 | EIF3F (eukaryotic translation initiation factor 3 subunit F) | protein interactions | 8665 | 91 | 28 | 17029 | 2761 |
EIF3L,IMMT,CYLD,PRRC2A,EIF3D,CSNK2A1,ATXN1,MCM2,CDK11B,EIF1B,EIF4G2,CDK11A,EIF3G,APP,EIF3H,EIF3A,WDR48,KIF2A,EIF3K,HUWE1,TIMM29,JOSD1,XRCC3,CLU,GLE1,NDE1,MCPH1,CD81 |
| 3.955e-04 | -7.84 | DHX30 (DExH-box helicase 30) | protein interactions | 22907 | 91 | 28 | 17029 | 2761 |
PPAN,COX15,STAU1,CYLD,KMT2E,IVNS1ABP,SUZ12,GSPT2,ILF3,CUL3,CUL1,NKRF,FAM136A,CAND1,NDUFA2,DGCR8,RPS14,RBM34,GRSF1,ZNF746,H2AFX,TARDBP,RRS1,GNAI2,MCMBP,ZC3HAV1,IFI16,GPATCH4 |
| 3.955e-04 | -7.84 | ESRRB (estrogen related receptor beta) | protein interactions | 2103 | 91 | 28 | 17029 | 2761 |
RPS2,PHB2,DNAJB2,ACSL3,TUFM,HNRNPF,TIMM21,NDUFA4,DNAJA1,SLC25A5,GNB2,TFRC,SSR1,PPP2CA,DNAJC10,ATP1A1,SEC61A1,ATP2A2,RPS27A,RPS14,LRPPRC,ATP5F1A,NCOA2,TUBB,SLC25A1,TIMM50,CDC37,TMEM33 |
| 3.955e-04 | -7.84 | RPLP0P6 (ribosomal protein lateral stalk subunit P0 pseudogene 6) | protein interactions | 220717 | 91 | 28 | 17029 | 2761 |
HSPH1,RPL29,RPS2,EWSR1,NOP2,RPLP2,RPS10,RPL6,RPL8,ILF3,RPL15,RPS24,MCM2,TARS,RPSA,MAT2A,RPL11,RPL23A,RPL32,RPS27A,RPL17,RPS14,RPLP1,RPL19,CHMP4B,RPS26,HNRNPM,LUC7L2 |
| 3.955e-04 | -7.84 | MOB4 (MOB family member 4, phocein) | protein interactions | 25843 | 91 | 28 | 17029 | 2761 |
CCT2,FGFR1OP,STRIP1,RB1CC1,VHL,SF3B1,DYNLL1,STRN4,SIKE1,MYO9B,MCM2,ELK1,DDX39A,CCT8,FADD,PPP2CA,PCM1,TIMM13,PDCD10,MED10,THAP4,CENPJ,CAB39,STK11,ZRANB1,ECPAS,CCDC59,FGFR1OP2 |
| 3.955e-04 | -7.84 | ITSN2 (intersectin 2) | protein interactions | 50618 | 91 | 28 | 17029 | 2761 |
BCCIP,WASF2,MRPL9,PDCD6IP,TM9SF4,TACC1,TRIO,WIPF1,LSM8,CHIC2,MAP4K3,PSEN1,RUFY1,ERC1,REPS1,DST,WAS,LTBP4,GOLGA2,SNAP29,LUC7L3,RBMX,TBL3,GOLGA8A,DNM2,AHDC1,ROCK1,AP2S1 |
| 3.972e-04 | -7.83 | GSE17974_0.5H_VS_72H_UNTREATED_IN_VITRO_CD4_TCELL_DN | MSigDB lists | GSE17974_0.5H_VS_72H_UNTREATED_IN_VITRO_CD4_TCELL_DN | 176 | 44 | 17377 | 2626 |
TMUB1,SCAMP3,DYNLL1,DCTN2,ACAP1,SNRPD3,GLRX3,MAD2L2,FBXO22,ARL6IP6,LIN9,CCNA2,SIVA1,BDH1,CAPZA1,TMEM99,MCMBP,MTX2,MSH6,PREB,NIPSNAP1,ZNF672,ANKRD37,GUK1,TMEM126B,MRPL43,CCDC34,GLO1,GALK2,NDUFA7,APPL1,SNRPA,KIF2A,SLCO4A1,SEC23IP,NSF,RAB24,LRPPRC,PGRMC1,DTD1,MDH1,APOL2,FAF1,STARD3NL |
| 3.972e-04 | -7.83 | GSE27786_LSK_VS_NKCELL_UP | MSigDB lists | GSE27786_LSK_VS_NKCELL_UP | 176 | 44 | 17377 | 2626 |
TMEM106C,PIGN,HMGXB3,FLYWCH2,FLOT1,RCOR3,SRRT,FBXO3,PDXP,DDX56,FBXL6,GART,COQ4,PHTF1,GPATCH1,KIFAP3,BCAP29,TAP2,GLE1,TTLL12,TDP1,PHF10,TK1,MLEC,PSPC1,LDB1,ACSL3,CCDC34,CDC23,CCNF,CLNS1A,GLOD4,RDH11,DTWD1,CDC16,PEX5,CDCA7L,HAGHL,H2AFX,RUVBL2,NDE1,PDSS2,IPO4,RHEBL1 |
| 3.972e-04 | -7.83 | GSE25088_ROSIGLITAZONE_VS_IL4_AND_ROSIGLITAZONE_STIM_STAT6_KO_MACROPHAGE_DAY10_UP | MSigDB lists | GSE25088_ROSIGLITAZONE_VS_IL4_AND_ROSIGLITAZONE_STIM_STAT6_KO_MACROPHAGE_DAY10_UP | 176 | 44 | 17377 | 2626 |
TRERF1,PPP1R12A,REPS2,RAF1,TMX4,MED13L,CCDC28A,SLC25A37,PAIP2,APLP2,PTEN,ARPC5,SNX18,NSFL1C,OSTF1,TAGLN2,TMEM8A,ZRANB1,GNAI2,TNRC18,RYBP,CYTH1,ZDHHC18,TIMP2,CIC,NEK7,RCOR1,UBE4B,BICD2,STX16,RXRB,MAN2A2,GNAS,MTMR3,HHEX,SCAP,UBXN2B,MRFAP1L1,ST3GAL2,WIPI2,MAP3K5,MAPK1,RTN3,DEF6 |
| 3.985e-04 | -7.83 | Osgep (O-sialoglycoprotein endopeptidase) | protein interactions | 66246 | 45 | 17 | 17029 | 2761 |
TP53RK,ZCCHC8,DYNLL1,CDT1,CHD1L,LAGE3,LAMTOR3,LYN,GAR1,SRRT,RPSA,PDCD6,STRBP,SEC61A1,TBC1D14,ICE2,NUMB |
| 3.985e-04 | -7.83 | NDUFA5 (NADH:ubiquinone oxidoreductase subunit A5) | protein interactions | 4698 | 45 | 17 | 17029 | 2761 |
COX15,EWSR1,BABAM1,CUL3,NDUFA4,ADRB2,DAZAP2,NDUFB1,VDAC1,APP,NDUFS7,RAB8A,NDUFA11,NDUFB9,DMWD,NDUFS5,DCTN1 |
| 3.985e-04 | -7.83 | Fus (fused in sarcoma) | protein interactions | 233908 | 45 | 17 | 17029 | 2761 |
DHX9,ILF3,SAFB2,SLTM,DDX17,HNRNPA2B1,PTEN,HNRNPR,RBMX,HNRNPH3,SAFB,ZNF326,DDX5,RBM3,RBM12B,HNRNPDL,HNRNPM |
| 3.985e-04 | -7.83 | NUP58 (nucleoporin 58) | protein interactions | 9818 | 45 | 17 | 17029 | 2761 |
MIB2,NDC1,NTPCR,NUP188,GOPC,ILF3,NUP54,LAMTOR3,TOMM40,NUP205,MAPK3,FBXO28,NUP107,NUP62,TOP1MT,IFI16,ABCC5 |
| 3.985e-04 | -7.83 | POC1B (POC1 centriolar protein B) | protein interactions | 282809 | 45 | 17 | 17029 | 2761 |
CCT2,TACC1,POC1A,CUL3,PIP4K2C,CIP2A,SUPT16H,PFDN5,FBXO28,PFDN4,PELO,SIL1,CORO1A,ZNF598,POC5,CDC37,NUDC |
| 3.985e-04 | -7.83 | TMEM173 (transmembrane protein 173) | protein interactions | 340061 | 45 | 17 | 17029 | 2761 |
ACSL3,IRF3,USP22,SURF4,DDOST,SEC61A1,STT3A,LTN1,USP20,MAVS,TRIM32,RNF26,CNNM3,IFI16,RNF5,USP13,ABCC1 |
| 3.985e-04 | -7.83 | MGA (MGA, MAX dimerization protein) | protein interactions | 23269 | 45 | 17 | 17029 | 2761 |
UNK,MAX,CYLD,PCGF6,E2F3,LSM8,MIER2,WDR5,CBX3,CDC16,MLX,E2F4,E2F1,SMAD1,ASB6,CBX4,RYBP |
| 3.985e-04 | -7.83 | ING2 (inhibitor of growth family member 2) | protein interactions | 3622 | 45 | 17 | 17029 | 2761 |
FOXK1,WDR5,APP,BRMS1,SAP130,SMAD2,PCM1,AHNAK,PCNA,SMAD1,RBBP4,SINHCAF,SMURF1,SAP30L,ARID4A,HDAC2,SAP30 |
| 3.992e-04 | -7.83 | TTLL12 (tubulin tyrosine ligase like 12) | protein interactions | 23170 | 57 | 20 | 17029 | 2761 |
CPNE1,UNK,RPRD1A,PPP1R12A,ACTR3,NSUN2,DNAJB1,TRIM28,DHX57,SRXN1,PPME1,TTC9C,TNPO3,ZRANB2,AHCYL1,UBE2C,RPRD1B,POC5,SSSCA1,USP34 |
| 3.992e-04 | -7.83 | CEP97 (centrosomal protein 97) | protein interactions | 79598 | 57 | 20 | 17029 | 2761 |
PLK1,ACTR3,RAB5B,LYN,HAUS8,CAND1,SUPT16H,CALM2,RAB8A,CEP104,PCM1,CDC16,CCP110,CENPJ,SNAP23,RAB35,ODF2,LTN1,TP53BP2,SASS6 |
| 3.992e-04 | -7.83 | GRSF1 (G-rich RNA sequence binding factor 1) | protein interactions | 2926 | 57 | 20 | 17029 | 2761 |
CYLD,MRPS2,MRPS15,MDH2,MRPS26,CUL3,CUL1,CHCHD2,ATP5F1B,CAND1,PTPN2,MRPL2,DAP3,IARS2,MRPS27,TARDBP,MRPL48,MRPL11,MRPL21,MRM3 |
| 3.992e-04 | -7.83 | TMED10 (transmembrane p24 trafficking protein 10) | protein interactions | 10972 | 57 | 20 | 17029 | 2761 |
CDKN2AIP,COX15,TMED7,COPA,APH1A,COPE,KRAS,GORASP2,NIT2,TMED3,ARF1,RAB1A,SDHA,COPG2,COPB2,NAGLU,LMAN1,CDK2,ATF2,TMED2 |
| 3.994e-04 | -7.83 | V$USF_C | MSigDB lists | V$USF_C | 265 | 61 | 17377 | 2626 |
HSPH1,MAX,DNMT3A,ANXA6,IVNS1ABP,ZFP91,UBXN1,GYG1,MXD4,DCUN1D4,STMN1,SLC20A1,RAPGEF6,PABPC4,DNAJB9,TFAP4,LYAR,PA2G4,PDK2,ZNRF2,UTP18,EFTUD2,SUCLG2,YBX1,RPL19,SLC26A2,FBL,PABPC1,NUDC,SOCS5,SRP72,EIF5A,AMPD2,PPP1R9B,POLR2L,LAP3,SIGMAR1,WBP2,SCFD2,NLN,PBRM1,ELK1,KDM3A,PSMB3,MAT2A,HMGN2,RXRB,ALDH3B1,HSPA4,CCDC6,LPCAT4,AEN,LRP8,ABCA1,THAP5,GCSH,IPO4,B4GALT2,SLC25A33,RHEBL1,ATXN7L2 |
| 4.005e-04 | -7.82 | TRIM33 (tripartite motif containing 33) | protein interactions | 51592 | 78 | 25 | 17029 | 2761 |
UBE2D3,TCF12,EWSR1,DCAF15,WDYHV1,TCF3,CHD1L,LDB1,VDAC2,CUL3,RRM1,CDC23,UBE2I,SUPT16H,SMAD2,CCNA2,CDC16,KLHL20,CDC27,SSBP3,MTA1,ANAPC7,SMAD4,ANAPC4,SSRP1 |
| 4.005e-04 | -7.82 | HINT1 (histidine triad nucleotide binding protein 1) | protein interactions | 3094 | 78 | 25 | 17029 | 2761 |
MIF,PPIB,UNK,EWSR1,TXN,RBX1,RAE1,UFC1,TKT,UBE2V1,NUTF2,FKBP2,SPR,PARK7,FKBP1A,CDC16,HINT1,HDAC7,DUT,PIN1,PRDX5,AKR1B1,TAGLN2,RUVBL2,GPX4 |
| 4.010e-04 | -7.82 | DUSP2 (dual specificity phosphatase 2) | protein interactions | 1844 | 23 | 11 | 17029 | 2761 |
EIF5A,DUSP3,PRDX5,ABHD14B,FKBP5,VPS4A,PTGES3,AP3S1,MAPK14,MAPK1,PARK7 |
| 4.010e-04 | -7.82 | PLD3 (phospholipase D family member 3) | protein interactions | 23646 | 23 | 11 | 17029 | 2761 |
HGS,TK1,HNRNPH3,TMEM216,LTN1,STK11,BCL2L1,PPP5C,SOX4,FUBP1,EVC2 |
| 4.010e-04 | -7.82 | EML4 (echinoderm microtubule associated protein like 4) | protein interactions | 27436 | 23 | 11 | 17029 | 2761 |
NEK6,FBXO28,NEK7,TKT,MIA2,PHKG2,EML4,TUBB,NUDC,DCTN1,TFEB |
| 4.010e-04 | -7.82 | TADA2B (transcriptional adaptor 2B) | protein interactions | 93624 | 23 | 11 | 17029 | 2761 |
TERF2IP,EPN1,TAF5L,TAF12,USP22,TAF6L,SUPT20H,SUPT7L,GGPS1,SGF29,TERF2 |
| 4.032e-04 | -7.82 | HTH_MYB | prosite domains | PS51294 | 9 | 6 | 12060 | 1670 |
MYBL1,TERF1,SNAPC4,TERF2,CDC5L,MYBL2 |
| 4.044e-04 | -7.81 | RHOC (ras homolog family member C) | protein interactions | 389 | 30 | 13 | 17029 | 2761 |
PPP3CA,RHOA,VHL,ARHGEF1,RAC1,ARHGDIB,ARHGEF12,CTSA,ROCK1,CDK2,ATF2,GNB2,RTKN |
| 4.044e-04 | -7.81 | MAPKAPK3 (mitogen-activated protein kinase-activated protein kinase 3) | protein interactions | 7867 | 30 | 13 | 17029 | 2761 |
PHC2,TCF3,RCSD1,PTPN7,MEF2A,PTPDC1,COPS6,MAPK14,BECN1,APP,CBX4,EEF2K,SRPK2 |
| 4.044e-04 | -7.81 | ARID4A (AT-rich interaction domain 4A) | protein interactions | 5926 | 30 | 13 | 17029 | 2761 |
BRMS1,RB1,CCNA2,FOXK1,RBL1,EID1,CCNB1,RBBP4,CDK2,SINHCAF,MXD1,HDAC2,SAP30 |
| 4.044e-04 | -7.81 | C6orf203 (chromosome 6 open reading frame 203) | protein interactions | 51250 | 30 | 13 | 17029 | 2761 |
SLC30A9,MRPL2,NDUFV1,MRPL9,MRPL16,MRPL40,MRPL21,MRPL13,APP,STRAP,MRPL32,ECH1,RCC1L |
| 4.044e-04 | -7.81 | MRPL34 (mitochondrial ribosomal protein L34) | protein interactions | 64981 | 30 | 13 | 17029 | 2761 |
MRPL50,RAP1A,MRPL9,C19orf53,MRPL42,MRPL39,KBTBD7,RPL6,RPL38,C8orf59,ZC3H3,APP,CSNK1G3 |
| 4.053e-04 | -7.81 | NDUFV2 (NADH:ubiquinone oxidoreductase core subunit V2) | protein interactions | 4729 | 53 | 19 | 17029 | 2761 |
NDUFS1,SEPT9,RAB7A,NDUFA4,NOTCH2,VDAC1,SDHA,NDUFS7,NDUFS4,SDHB,NDUFV1,NDUFA2,SYNCRIP,NDUFB4,NDUFA11,SUCLG2,NDUFS8,NDUFS5,PITRM1 |
| 4.053e-04 | -7.81 | CCND3 (cyclin D3) | protein interactions | 896 | 53 | 19 | 17029 | 2761 |
MCM10,TSC2,RBX1,POLR3GL,CDK11B,APP,FAS,EIF3K,CDKN2C,CDK5,RB1,PCNA,MAPK6,AKAP8,CDKN1B,SIL1,CLU,CDK2,NCOA2 |
| 4.055e-04 | -7.81 | SERPINH1 (serpin family H member 1) | protein interactions | 871 | 100 | 30 | 17029 | 2761 |
COX15,UBQLN4,STAU1,CYLD,MDH2,TCF3,TPX2,KLF13,RCOR1,BRCA1,LANCL1,ADRB2,TOMM40,MCM2,VDAC1,SPR,SDHA,STAM,ZFR,HNRNPA2B1,UBTF,SUGP1,SEC24C,NABP2,AHCYL1,PDIA6,CDK2,ATF2,CFL1,HDAC2 |
| 4.056e-04 | -7.81 | Shoc2 (soc-2 (suppressor of clear) homolog (C. elegans)) | protein interactions | 56392 | 49 | 18 | 17029 | 2761 |
CLPTM1,SHOC2,GLT8D1,PNISR,HNRNPAB,REPS2,FOXM1,NACA,CDCA3,SUB1,GALNT2,KPNA4,JAK1,RBMX,LTN1,MRPL48,FUS,PDF |
| 4.056e-04 | -7.81 | MAGEB10 (MAGE family member B10) | protein interactions | 139422 | 49 | 18 | 17029 | 2761 |
CDKN2AIP,STAU1,NOP2,RPLP2,RPL6,GTPBP4,RPL15,LLPH,PRKRA,BRIX1,LYAR,DDX56,GOLGA2,RPL32,RPL17,NOC2L,H2AFX,DDX31 |
| 4.056e-04 | -7.81 | PAWR (pro-apoptotic WT1 regulator) | protein interactions | 5074 | 49 | 18 | 17029 | 2761 |
SCOC,AATF,SNX2,MYH9,JMJD6,PAWR,IKBIP,DDX39A,HMG20A,DAPK3,CAND1,IDE,PPM1G,STAT1,PML,ATP6V1C1,H3F3A,VPS29 |
| 4.056e-04 | -7.81 | CSDE1 (cold shock domain containing E1) | protein interactions | 7812 | 49 | 18 | 17029 | 2761 |
UNK,NUP188,UGP2,CUL3,PCSK7,CUL1,BRCA1,ATP6V1B2,PAIP1,XRCC5,WWP2,SYNCRIP,STT3A,HUWE1,SEC24C,PABPC1,STRAP,SSRP1 |
| 4.056e-04 | -7.81 | TANK (TRAF family member associated NFKB activator) | protein interactions | 10010 | 49 | 18 | 17029 | 2761 |
PLK1,SRSF11,USP7,BIRC3,PBXIP1,SUMO2,USP10,RACGAP1,IRF3,APP,BIRC2,TAB2,TANK,TICAM1,KPNA2,TP53BP2,CEP63,MAP3K14 |
| 4.067e-04 | -7.81 | GSE40685_NAIVE_CD4_TCELL_VS_TREG_UP | MSigDB lists | GSE40685_NAIVE_CD4_TCELL_VS_TREG_UP | 166 | 42 | 17377 | 2626 |
RMND5A,MMACHC,NQO1,KIAA0100,RPLP2,MRPS2,MRI1,ZNF416,SDC2,PPP1R16B,RPL23A,CAPN2,DNAAF2,ARHGEF1,FBL,TOP1MT,TMEM9,TACC3,GPX4,TSHZ1,EIF3L,RPL35,MAP4K4,RPL6,MTMR12,ESYT1,PCGF1,CCNF,USP36,RXRB,MAGED2,UBTF,MAP3K4,TTC13,SCAP,NIP7,EIF2D,CAMKMT,RRS1,PITRM1,SAT2,FAF1 |
| 4.080e-04 | -7.80 | Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins | REACTOME pathways | R-HSA-176814 | 77 | 25 | 10287 | 1696 |
PLK1,PSMA8,PTTG1,PSMB7,PSMA1,ANAPC2,CDC23,CCNB1,PSMD9,PSMB9,PSMB3,PSMC4,PSMD2,PSMA6,CCNA2,CDC16,PSMD1,CDC27,RPS27A,PSMD8,PSMD3,ANAPC7,UBE2C,PSMC1,ANAPC4 |
| 4.095e-04 | -7.80 | YAGI_AML_WITH_T_8_21_TRANSLOCATION | MSigDB lists | YAGI_AML_WITH_T_8_21_TRANSLOCATION | 352 | 77 | 17377 | 2626 |
TSC2,UGP2,AGRN,RPS6KA1,TGOLN2,BCL2L1,AP1B1,EXT2,APP,SSR1,ANKRD28,CDKN2C,NUP210,SHC1,RALB,DPYSL2,ETV6,RAB4A,SEPT11,TTC3,APOOL,ZC3H3,ARID4A,ADCY7,SAP30,ANKLE2,KDM3B,ORAI2,PBXIP1,NCK1,ERF,SELPLG,MKI67,ATXN1,GLO1,EPB41,AGPAT2,JAK1,CERS6,TRIO,GNE,CRLF3,MAN1A1,TFAP4,NDUFA2,SLC1A4,TIMELESS,YBX1,CLDND1,SLC25A1,SOCS5,ABCC1,VOPP1,CSNK1G2,ACP2,MAPKAPK3,USP10,MACF1,DDX39A,PSMB3,SH3GLB1,MAGED2,GNAS,UTP20,FBXO21,NAP1L1,GALNT2,POLR2J,ELMO1,GPS2,CSK,COX8A,LY75,HEXA,ESPL1,ADNP2,SMARCD1 |
| 4.101e-04 | -7.80 | GO_MYELIN_SHEATH | MSigDB lists | GO_MYELIN_SHEATH | 161 | 41 | 17377 | 2626 |
MIF,NDUFV2,IMMT,NDUFS1,PDCD6IP,MDH2,TKT,SLC25A12,SIRT2,ATP6V1B2,GNB2,SDHA,CD59,NAPG,RAP1A,CDC42,PTEN,GOT2,DPYSL2,AKR1B1,BCL2,LDHB,CCT2,IDH3A,WDR1,VDAC2,EZR,SEPT8,VDAC1,SLC25A5,PRDX1,ATP1A1,NSF,PRDX3,EXOC4,ITGB1,COX5A,PITPNA,MDH1,GPI,PGAM1 |
| 4.101e-04 | -7.80 | GSE3720_LPS_VS_PMA_STIM_VD1_GAMMADELTA_TCELL_DN | MSigDB lists | GSE3720_LPS_VS_PMA_STIM_VD1_GAMMADELTA_TCELL_DN | 161 | 41 | 17377 | 2626 |
MIF,GPR132,GMFG,CXXC1,TRIO,KLF13,CDIPT,RAPGEF6,KTN1,FANCL,MCM5,ZNHIT6,TACC3,PDCL3,PDLIM2,METTL1,TGFB1,RPL29,NASP,RNASEH2C,EMB,RPS10,PSMG1,MEF2D,LY6E,H2AFV,EIF3G,RPSA,SH3BP5,MRPL2,BOLA3,MID1IP1,RPS14,MRPL27,COX5A,CHMP4B,MAP3K5,FAU,RPS26,STARD3NL,POLQ |
| 4.115e-04 | -7.80 | FGFR1OP (FGFR1 oncogene partner) | protein interactions | 11116 | 146 | 40 | 17029 | 2761 |
FGFR1OP,MAPRE1,GOLIM4,TATDN3,KLC1,BLM,LYN,WRNIP1,GNS,DLG5,VASP,SYNM,TXLNA,DNM2,GPATCH1,TTC3,CEP63,CARMIL1,PLK1,MOB4,MIOS,CCDC138,FOPNL,ADSL,PACS1,BRCA1,RAB3IP,HAUS8,AKAP1,PPP2CA,PCM1,CCDC14,TIMM29,HPS5,ODF2,EXOC4,KIAA1328,TAF12,BTF3,SASS6 |
| 4.115e-04 | -7.80 | BSG (basigin (Ok blood group)) | protein interactions | 682 | 146 | 40 | 17029 | 2761 |
NOP9,EXOC3,CYLD,EWSR1,C19orf25,DNAAF5,XPO7,RSAD1,FASTKD3,PPIL2,PDS5B,INTS12,PARL,ABCD1,KNTC1,ATF2,GPD1L,CTDSP2,TELO2,FAM118B,BTAF1,VHL,CUL3,RFXANK,COG1,TBRG4,SYVN1,MTX1,VDAC1,SYMPK,DDX23,CAND1,UTP20,RAD51C,HGS,EXOC4,SEL1L,SLC16A1,ECPAS,APOL2 |
| 4.116e-04 | -7.80 | GO_NEGATIVE_REGULATION_OF_RESPONSE_TO_DNA_DAMAGE_STIMULUS | MSigDB lists | GO_NEGATIVE_REGULATION_OF_RESPONSE_TO_DNA_DAMAGE_STIMULUS | 48 | 17 | 17377 | 2626 |
MIF,PGAP2,BCL2L12,BRD4,TRIP12,THOC1,HELB,BCL2L1,PTTG1IP,MDM2,CHEK2,CLU,TRIM32,OGG1,RNF169,POLQ,TERF2 |
| 4.116e-04 | -7.80 | REACTOME_REGULATION_OF_ORNITHINE_DECARBOXYLASE_ODC | MSigDB lists | REACTOME_REGULATION_OF_ORNITHINE_DECARBOXYLASE_ODC | 48 | 17 | 17377 | 2626 |
NQO1,PSMA8,PSMB7,PSMA1,ODC1,PSMB9,PSMD9,PSMB3,PSMC4,PSMD2,PSMA6,PSMD1,PSMD3,PSMD8,OAZ2,OAZ1,PSMC1 |
| 4.116e-04 | -7.80 | HELLER_HDAC_TARGETS_DN | MSigDB lists | HELLER_HDAC_TARGETS_DN | 276 | 63 | 17377 | 2626 |
DNAJC2,CYTIP,HSPH1,MAGEH1,HNRNPAB,RRP15,KLHL21,ANK3,UCK2,CUL1,GTF3A,BCL2L1,DNAJB1,IL21R,ITGB5,PPP1R16B,ABHD14A,PNO1,DNAJB9,CFLAR,CAPN2,FGFR3,TNS3,NUP210,SLC1A4,ATIC,GTSE1,CDKN1B,BCL2,EIF5,ADCY7,NOL12,PLK1,PPIF,EIF5A,POU2AF1,SELPLG,TLK1,MFNG,GBA,MYBL2,WIPF1,EMP3,ARHGDIB,CADM1,EIF4G2,SERP1,HSPA1B,FAS,DDX17,SLC19A1,WNT5B,CEBPG,OGT,CCDC69,GAS2,RRS1,ZMIZ1,LRP8,EYA2,MRPL3,CBX4,PFKP |
| 4.117e-04 | -7.80 | transitional_cell_carcinoma | COSMIC cancer mutations | transitional_cell_carcinoma | 6196 | 998 | 17385 | 2587 |
CCDC93,HECA,ADD1,TSC2,KDM4A,ABCC10,PIGQ,HEXB,CNTROB,PPP1R16B,PABPC4,EEF2K,CALM2,USF1,GSDMB,RABGAP1L,TTC9C,MECR,PDS5B,DNM2,CRY2,NUP153,RNF26,LRRC59,TIPARP,FTSJ3,PCBP2,USP34,PLK3,ZNF672,ERCC1,ZNF559,NRAS,GABPA,EHMT1,HSDL1,KIF15,HNRNPF,PLEKHM3,SMC2,DIDO1,PPFIA3,WBP1,KRIT1,BRMS1,AHNAK,MID1IP1,RAD18,ZNF689,LIMK1,PRDX5,OGT,COX5A,RNASEL,SMG9,FBXL3,SMAD1,ANXA11,PFKP,SLC25A33,DDX42,HIVEP3,NDUFV2,CLSPN,KIAA0100,GGA1,TRIO,CUTA,HAUS4,SLC4A2,EIF2AK4,APH1B,CDC73,MYL6B,ATG4A,CD59,DDX56,SMC3,RNFT1,FBXO7,FOXN2,NUP85,PABPC1,CARS2,TIMM8B,AGGF1,RB1CC1,ZMYND11,DHX29,MTA2,TEX10,MAN1B1,GTPBP4,MYBL2,UHRF1BP1,MRPL16,CBFA2T2,MPG,ELK1,SFXN5,RHOB,PTPRF,SCARB2,FNTA,KPNA1,CCDC86,SETD3,ZNF830,HEXA,SNX14,RNF139,MRPL3,ALS2,EGLN1,ZNF207,RHOG,ZNF296,TRIM41,ABCA3,TRERF1,IVNS1ABP,UBR2,ACTR3,ANK3,WDTC1,MON1B,C5orf30,MYH9,CREBL2,TBC1D13,NIPA2,NIT2,SLC35B2,PRKACA,STAM,REPS1,APP,PRKD3,ZNF420,AHCTF1,ATP2A2,SP100,TBC1D22A,ZKSCAN1,SH3BP1,UTP18,NUP107,ANKRD13C,ANAPC7,RNF19A,CEP63,FAM76B,MAVS,GPD1L,ZC3H3,GCC1,ARL5A,DCTN1,ADCY7,ENPP4,SNX8,CPNE1,FAM118B,IDH3A,CRNKL1,POLR2D,PFKFB3,ATP6V0A1,HTATIP2,CDCA2,MEF2D,TMEM147,TANC1,GIGYF1,GPR137,DDX17,TAF2,VPS26B,NSMCE2,CORO1C,CAMKMT,WDR7,RNF38,MBOAT1,ZBTB11,USP13,TMBIM4,ZFP91,TRMT6,CCM2,TRAK1,SIKE1,ATG2B,JMJD6,PMVK,KRI1,PPP1R3B,FBXO3,ZBTB45,ITGB8,GATC,HUWE1,PPP1R8,ARHGEF1,LTN1,UBE3B,TTLL12,TPCN1,LYPLA2,SPTAN1,NUDC,STAU1,PPP3CA,DDX24,GALC,ZNF512,MRS2,DDX39A,PDE3B,RPA1,UTP20,SLC19A1,ZNF180,POLE,ACOX1,TATDN2,MAPK6,LRPPRC,LY75,HMGB2,THAP5,FAF1,ANAPC4,AGRN,WDR13,TRIM11,PPP1R15B,FAM129A,YTHDC2,SNX15,RBM8A,MCCC1,CSNK2A1,EBNA1BP2,SND1,S1PR2,GIT2,BIRC2,ATPAF1,KRR1,FANCL,ABL2,DLG5,NUP210,GLIS2,NT5DC1,PIK3R2,ASB6,MRPL32,CCAR1,ABCC5,VPS13B,PTPRK,PLK1,METTL1,CELSR2,MIOS,HARS,MBLAC2,GMFB,LNX2,CDC6,LRP5,PBRM1,BRCA1,ESYT1,ANLN,USP21,LSG1,RHEB,DPYSL3,EPB41,TRAM2,TBC1D17,TIMM13,TONSL,E2F4,ADAM9,QRSL1,ACTB,DVL1,CLN3,FAM208A,NUDT11,NUMB,CTU2,PARP12,ZCCHC9,FAM53C,DNAJB2,CENPF,CTCF,KLC1,ASAH1,RACGAP1,CDK13,RAB6A,NCKAP1,PPP3CB,B4GALT4,DOCK11,RLF,RAPGEF6,LRRC14,TNS3,RB1,C1GALT1,UBE2Q2,VMP1,RINL,ZNF746,PPIL2,TIMELESS,CTR9,AHCY,MDFIC,AHDC1,MAML1,LRSAM1,NIPSNAP1,ABCC1,NTPCR,TRAPPC9,NQO2,ACSL3,LDB1,MEMO1,KRAS,EIF2AK1,RTF1,METTL22,EIF4G2,ARMC8,IRF5,ZNF174,NMT2,PSMC4,GOLGA4,TMEM168,CDC27,NLRC5,FAM122A,PRMT7,SIL1,BTBD10,KCTD7,RPLP2,UGP2,ARID2,FOXM1,XAB2,SLC2A1,TM9SF3,ZADH2,GGPS1,PCBP1,LYN,COMMD8,RAD23A,VAV1,OIP5,CSDE1,PDK2,MDM2,ZNF473,STRBP,BRPF3,WDR44,PDCD2,RPAP1,BCAP29,CABLES2,TOP1MT,AHCYL1,ZNF583,SPSB3,DVL2,SNX25,KDM3B,CLPTM1,MND1,BIRC3,SLC26A6,NUP155,VDAC1,KDM1B,RPSA,USP36,RHBDF2,SUGP1,DNAJC10,IDE,CLK3,RBL1,SCAP,ZNF700,PSMD3,CEP55,ZNF436,XRCC3,LTA4H,USP53,SMAD4,PARD3,ZC3HC1,BCL2L12,SLC30A9,GOLIM4,GNE,ARID5A,ARFIP2,SUMF1,SLC12A9,GGA2,RMI1,BZW2,SCYL2,TUBGCP2,DNAJB9,TFRC,GTPBP3,NDUFV1,SLC1A4,CWC27,ABCD1,ORC3,CAMK2G,RBM15B,YTHDC1,RPAP3,PPAN,RPRD1A,RHOA,ACP2,CSRP1,SNX2,BTAF1,ZNF202,ZMYM5,ABCF2,TOP3A,CCDC34,ARHGEF12,RANGAP1,PCGF1,DDX23,CACNB1,KPNA4,CDKN2AIPNL,SEC23IP,BIRC5,TWSG1,SNAP29,NEIL3,BBX,CDCA7L,FAM126A,NR2F2,HIPK3,SAT2,NUP188,MAX,PNISR,NDUFB6,GXYLT1,PRKCSH,ADAM10,TMEM41B,CXXC1,CUL1,NHLRC3,PLXNA1,EIF1B,SLC20A1,MYEF2,POLR3K,C14orf119,ANKRD26,ZNF428,PA2G4,SNUPN,ASAP2,NOL11,DBNDD1,PARPBP,TRA2B,SUCLG2,TAF5L,SLC26A2,DNMT1,SRP72,ZNF524,SGCE,OSBP2,KLF10,ATG9A,AKT2,NSUN2,MKI67,DDX20,AMDHD2,SLC17A5,AURKB,USP22,FOXRED1,RFC2,SLC25A5,RAB2B,EIF3A,IWS1,DOT1L,ZMYM3,MAP3K4,HHEX,WAS,RBM47,TPP2,WDR4,PTPDC1,ARRB2,RTN3,NMD3,HDAC2,PTOV1,DDX58,WSB2,PPIB,HSPH1,PRPF38B,MAPRE1,EWSR1,MUT,PRKAA1,ANKH,DLGAP4,TATDN3,B4GALT1,KIF23,NDUFA4,NOTCH2,TMEM165,ZNF79,PDXDC1,VPS25,NDUFS7,JMY,WDR48,RTKN,CFLAR,FAM192A,RPN1,EXOSC7,LHX8,KLHL5,LRRC8D,HDAC7,BDH1,MSH2,DAPK1,PIGG,TPST1,CYC1,PIK3IP1,PIKFYVE,ANKHD1,FAM171A1,SYTL3,TMED2,MORC3,SOCS5,PRIM2,ZNF84,RDH10,ZNF574,MFNG,EXOSC9,RIT1,ADRB2,CAPZA2,ARID1A,PLEC,PKM,KDM3A,GOSR1,MAP2K2,CCT8,MTR,PHF6,ADSS,ZNF777,MTHFD2,HSPBP1,GOLGA2,NSF,RBMX,MED15,ACLY,USP32,FAM83D,APPL2,ARAP1,VCPIP1,CABIN1,SMPD4,GPI,MAP3K5,PPP6R2,CDKN2A,ZC3HAV1,DNMT3A,ATXN3,CKLF,REPS2,TRIP10,URB2,SF3B1,RAF1,CAST,SUZ12,RPS6KA1,MAGED1,UROD,KIAA0232,OLA1,AP1B1,SNN,SDHA,GNB2,PHC2,NUDT19,CRKL,TERF2IP,ZNF75D,SHC1,RALB,MTMR4,UCHL5,LPIN2,ADCY9,CDKN1B,BRI3,TTC3,AQR,RBM12B,ILKAP,CDK12,SAP30,ANKLE2,CCT2,CDKN2AIP,MKLN1,HMGN4,ERF,OAF,CUL3,ELP4,SLBP,KIAA1586,EDF1,PKMYT1,GALK2,CDC23,H2AFV,ERC1,DHX57,SUPT16H,ANKZF1,CHMP4A,JAK1,DSN1,HAGHL,PPA2,STAT1,SEL1L,RWDD4,H2AFX,ATF6,KLHDC4,TRIM32,PDCD11,ATMIN,PRPF4B,ANKRD13D,PKP4,NDUFS1,DEPDC1,MECP2,TKT,CBLL1,SLC25A12,ARGLU1,SECISBP2,BLM,SPR,POFUT1,HMG20A,REEP5,FAM8A1,HEATR5B,JAKMIP1,WWP2,MAT2B,RBM17,PTEN,CRAT,CENPJ,FUT8,AXIN2,PTPN11,MRPL54,COPS7B,CNN2,CITED2,MSH6,SMC4,ANKRD37,LONRF3,DENND4C,NET1,DENND1B,ILF3,RFXANK,BMS1,OTUD3,LRRC1,RHOT1,KLF6,GUF1,MACF1,MARK2,MYO1F,NUCB1,FBXO21,SGSH,HGS,PRDX3,TTLL4,ZHX1,TFDP1,DDX5,WDR91,TAF6,ESPL1,PURA,DDB1,FAM83G,DEF6,ESYT2,MIB2,NAT9,SKA3,HNRNPAB,PLXNC1,UBN1,NF1,MOGS,DNAJC24,TAF6L,KIF2C,USP48,BECN1,SNAPC4,RNF103,ZNF696,EDC3,BCAT2,MBD4,ZNF804A,DST,GOT2,SIVA1,ZNHIT6,GPATCH1,AKR1B1,NDUFB9,CNNM3,ARID4A,TRIM14,WDR41,TIMM50,LARS,SNRNP200,LAP3,VHL,LRBA,SUMF2,PITPNB,KMT2C,OGFR,SOX4,ASF1B,ABHD5,RPL37,UBTF,CXXC4,MAN2A2,PAF1,EIF4ENIF1,BRWD1,SPATA2,PPM1G,SH3GLB2,MIA2,ATXN2L,BAZ1B,ACBD4,STK11,CLU,CHEK2,TSTD2,SLC12A7,PPP1R2,TM9SF4,NACA,TIA1,MED13L,THRAP3,XPNPEP3,EPHX2,TTF1,SRRT,QSOX2,NUP205,CHKA,DTL,ZNF449,MED10,CAPZA1,ZNF335,KIFAP3,BCL2,UBE3C,ZRANB1,SLC12A2,POLR2I,TSTA3,CIC,SUGP2,GBA,SLTM,ARHGAP15,EVC2,CAND1,MASTL,GNAS,TSC1,NAP1L1,RBM25,NSMF,ODF2,EXOC4,SLC16A1,FN3KRP,PITPNA,NUP62,NAA20,PTDSS1,C7orf26,N4BP2L2,MBD1,TCF12,WASF2,PRKAB1,ASH1L,CORO7,MPHOSPH8,CHERP,WDYHV1,HNRNPUL2,UCK2,PMS2,SMARCA4,PLAGL2,CHKB,CLCC1,MXD1,PAIP1,USP5,SAP130,HNRNPA2B1,FARSA,IARS,NVL,CD3EAP,KIF14,EXOSC1,RPN2,CHTOP,PDIA6,SCYL3,HTRA2,MOSPD1,RLIM,POU2AF1,ACSL5,ZNF500,NLN,ATXN1,OGDH,CADM1,BICD2,HERPUD2,EDEM2,MBD3,GFER,EIF3G,RPS9,BTBD1,RAD54B,PON2,ZNF317,HPS5,STAT6,TULP3,WDR59,ARNTL,CANT1,FKBP5,TMEM101,GAS2,USP11,AKNA,SMURF1,MAPK1,ABCA1,TSPAN5,CBX4,KIF3B,TRIP12,SH2D3A,EYA1,SHPRH,CDK2AP2,SCYL1,LETMD1,PAWR,DCUN1D4,MFSD10,HDDC2,FERMT3,KIF5B,FGFR3,GART,SEC24C,PPIG,RRBP1,TANK,PELO,H2AFY,ARHGEF2,BRD7,ATG13,TTC17,FBL,FRMD8,MYO5A,TELO2,CSNK1G2,DCAF6,ADAM17,TMEM39A,HELB,ASPM,ATP2C1,PPP1R21,RFFL,COG1,WDR81,PRMT2,NDRG3,SYMPK,LEMD2,HLA-B,UPF1,ATAD2,PLAA,ELMO1,OSBPL8,ZNF330,ZC3H7B,ACAT1,MBD6,SRSF3,CENPT,ZMIZ1,IDH3B,ATP6V1C1,HRAS |
| 4.129e-04 | -7.79 | GSE11818_WT_VS_DICER_KO_TREG_DN | MSigDB lists | GSE11818_WT_VS_DICER_KO_TREG_DN | 141 | 37 | 17377 | 2626 |
CYLD,TOR3A,YTHDC2,SDC2,KLHL18,NENF,CLCC1,AP3S1,DUSP22,ASXL2,PCBP1,SNAPC4,TUBGCP2,TFRC,CREM,MRPL50,HERC3,DDX56,GART,PTPN11,SUCLG2,DNMT1,MKLN1,GALC,ERLIN1,HNRNPF,LSG1,CHCHD3,SEC23IP,SMAD2,RAD18,RPL32,WDR11,RPS14,CRCP,ATE1,CWC25 |
| 4.140e-04 | -7.79 | mRNA splice site selection | biological process | GO:0006376 | 28 | 12 | 17256 | 2622 |
YTHDC1,RBMX,SRSF6,LUC7L3,KHDC4,SRSF5,PRPF39,LUC7L,SF3A2,LUC7L2,SRSF1,SRSF10 |
| 4.140e-04 | -7.79 | peptidyl-lysine trimethylation | biological process | GO:0018023 | 28 | 12 | 17256 | 2622 |
TET3,KMT5C,SUV39H2,SETD3,ZNF335,OGT,KMT2B,CTR9,RTF1,WDR82,BEND3,ARID4A |
| 4.140e-04 | -7.79 | regulation of transcription involved in G1/S transition of mitotic cell cycle | biological process | GO:0000083 | 28 | 12 | 17256 | 2622 |
RB1,PCNA,BRD4,E2F4,CDT1,TFDP1,E2F1,RRM2,CDC6,ORC1,TFDP2,FBXO5 |
| 4.162e-04 | -7.78 | AAGCACT,MIR-520F | MSigDB lists | AAGCACT,MIR-520F | 223 | 53 | 17377 | 2626 |
HIVEP3,KIF3B,ZFP91,MECP2,UBXN1,KLHL18,YTHDF3,LETMD1,PLXNA1,ARF1,C19orf48,RAB11A,APP,PAPOLA,TFAP4,RAP1A,UBE2Q2,MEX3C,ZKSCAN1,IL6ST,JAZF1,PRDM4,PRC1,H2AFY,CDKN1B,SS18L1,TARDBP,CDC25B,MAP3K14,TIPARP,ZNF800,SENP1,ARID4A,YTHDC1,DCAF6,RB1CC1,USP42,PICALM,RAB22A,ASF1B,MTMR3,SUGP1,ZNF180,ATAD2,RBL1,OSBPL8,ZNF436,CNOT6,RGL1,SLC22A23,ZBTB11,ABCA1,ATXN7L2 |
| 4.163e-04 | -7.78 | negative regulation of gene expression | biological process | GO:0010629 | 1873 | 335 | 17256 | 2622 |
TXN,ZNF496,MAX,H2AFZ,KDM4A,TSC22D3,XIAP,YTHDF3,CCNB1,UBE2I,RBM4,PARK7,RPL23A,CDK5,PA2G4,CIPC,SRSF4,TRA2B,CRY2,FNIP2,SMARCE1,TIPARP,DNMT1,SRSF10,BAK1,PLK3,KLF10,GABPA,EHMT1,DDX20,AURKB,DOT1L,BRMS1,HHEX,SMAD2,RPS27A,RPS14,AXIN1,PRDX5,SMG9,TFDP2,SMAD1,HDAC2,PDCD4,GSPT2,PRKAA1,DHX9,EIF2AK4,NOTCH2,PARN,PSEN1,METTL3,CDC73,CNOT3,DDRGK1,TFAP4,CD59,EXOSC7,MEX3C,KLF16,HDAC7,PHF14,DAPK1,TNRC18,PABPC1,TERF2,RBM42,ETV3,FOXK1,MTA2,RPS10,RPS24,BCLAF1,EXOSC9,ARID1A,CBFA2T2,FXR1,PATL1,MAP2K2,PHF6,XRCC5,EPRS,PFDN5,ETS2,RBMX,QARS,CNOT6,YY1,CDK2,RNF139,CDKN2A,ZNF296,DNMT3A,GGNBP2,UBR2,CAST,SUZ12,MAGED1,WDTC1,RCOR3,APP,PAIP2,SPINDOC,SHC1,SP100,CDKN1B,RBM15,ATF2,CGGBP1,SAP30,CPNE1,ERF,EID1,DRAP1,RPL38,CUL3,RNPS1,POLR2D,CIRBP,H2AFV,TRIM28,DDX17,PPP2CA,CHCHD3,ZNF282,DGCR8,LSM6,NT5C3B,HIPK2,H2AFX,RPLP1,STAT1,BEND3,LRP8,POU3F2,NCOR2,RPS2,DEPDC1,SRSF6,MECP2,TCF3,HMG20A,FOXO3,MAD2L2,TUT4,WWP2,PDCD10,ITGB8,SUV39H2,RPL17,DCP1A,RPL19,UPF2,CITED2,CNOT6L,CREB1,NCOA2,TSHZ1,PPP3CA,ILF3,RPL8,KCNQ1,ZP3,RPL27A,PICALM,CBX3,RPL32,GPS2,ZHX1,PITX1,PML,KHSRP,DDX5,HMGB2,PARP10,IGBP1,CPEB2,PURA,RORB,TRIM11,RBM8A,SND1,SIRT2,BIRC2,EDC3,CREM,PRNP,GLIS2,EIF4A3,JAZF1,METTL14,ZNF639,ETV6,NOC2L,SLC35C2,ARID4A,PTPRK,RYBP,PLK1,SP3,DEAF1,EXOSC6,BAZ2A,NCK1,PBXIP1,VHL,RIOX2,EZR,BRCA1,PRKRA,RPL37,PAF1,EIF4ENIF1,ZNF268,BEND6,RPS26,ZNF564,UBE2D3,RPS15,PHB2,CENPF,TIA1,RPL15,CTCF,MEF2A,DNAJB1,THRAP3,CNOT11,SRRT,PRPF18,LYAR,RB1,MLX,NFATC3,MBD2,ZNF746,CTR9,TIMELESS,YBX1,MDFIC,MCPH1,ZNF189,CIC,LDB1,RPL6,RTF1,EIF2AK1,DAPK3,ZNF174,RPL36,TSC1,SYNCRIP,NFIL3,ZFP90,RBBP4,TOB1,N4BP2L2,MBD1,MPHOSPH8,RPLP2,FOXM1,SMARCA4,IRF3,DUSP22,MXD1,PAIP1,RPL11,HNRNPA2B1,SAP130,CSDE1,ZBTB21,MDM2,EXOSC1,TARDBP,STRAP,RLIM,MOSPD1,RPL29,RPL35,BIRC3,FAM172A,POLR2G,ZNF500,BTG2,PCGF6,ATXN1,NFATC2,MBD3,RPS9,RPSA,RBL1,HNRNPR,MAFK,STAT6,ARNTL,DNAJC17,H3F3A,SMAD4,CBX4,MIF,BCL2L12,UNK,DAP,AGO2,ARID5A,PAWR,NKRF,MXD4,PTPN2,KMT5A,PELO,BRD7,H2AFY,STAT3,RBM15B,SAMD4B,TGFB1,ZNF202,PSPC1,BTAF1,RCOR1,PRMT2,MEN1,HSPA1B,CNOT9,UPF1,BIRC5,ZC3H7B,GLG1,E2F1,KMT2B,RBPJ,NR2F2,HRAS,IFI16 |
| 4.179e-04 | -7.78 | smooth_muscle | COSMIC cancer mutations | smooth_muscle | 53 | 18 | 17385 | 2587 |
EWSR1,NRAS,NF1,SF3B1,KRAS,BRCA1,GNAS,CDKN2C,RB1,JAK1,PTEN,JAZF1,ETV6,PTPN11,STK11,FUS,HRAS,CDKN2A |
| 4.179e-04 | -7.78 | immune effector process | biological process | GO:0002252 | 916 | 176 | 17256 | 2622 |
ADA2,RAB14,KMT2E,ADAM10,TRIM11,HEXB,NHLRC3,GYG1,BECN1,MAPK14,KCMF1,CMTM6,POLR3K,ELMOD2,PA2G4,RAP1A,PSMD1,CDC42,PIK3R2,AP1M1,PLCL2,KCNAB2,PCBP2,ERCC1,EXOSC6,NRAS,NCK1,ARHGAP45,CYSTM1,RAB5B,WAS,AGPAT2,LIMK1,PQBP1,CRCP,CAB39,ATP6V0C,ACTB,RNASEL,ROCK1,CLU,CAPN1,SVIP,DDX58,DNAJC5,GMFG,VAV2,LAMTOR3,B4GALT1,ASAH1,CDK13,MAN2B1,NOTCH2,EIF2AK4,NCKAP1,RAB6A,DOCK11,PSEN1,TMEM179B,GNS,CD59,ARPC5,MSH2,BCL2,OSTF1,MVP,LPCAT1,KDELR1,CYFIP1,FTL,CREG1,WDR1,ZMYND11,MFNG,ITM2A,C1orf35,PKM,CYFIP2,ARPC1A,ARMC8,CCT8,ISG15,IRF5,PI4K2A,XRCC5,CAND1,CAT,TSC1,SNAP23,ACLY,CEBPG,NLRC5,CTSA,GPI,ZC3HAV1,WASF2,RHOG,KARS,DYNLL1,RAC1,ACTR3,NIT2,IRF3,LYN,APP,CPNE3,VAV1,BRI3,MAVS,CORO1A,ABI1,TMBIM1,GM2A,CPNE1,ENPP4,CCT2,TIMP2,CGAS,RAB7A,PPIE,PSMB7,ATP6V0A1,WIPF1,CADM1,TOLLIP,DDX17,ALDH3B1,DSN1,SURF4,DDOST,RAB24,PSMD3,STAT6,STAT1,CANT1,TICAM1,PDXK,LTA4H,MAPK1,TUBB,MIF,MANBA,PDAP1,PSMD2,IRF4,CTSS,HUWE1,CNN2,MAP3K14,STAT3,MSH6,SPTAN1,ADAM17,RHOA,MLEC,DENND1B,ILF3,HEBP2,ZP3,PRDX1,FADD,NEU1,HSPA1B,MAPK3,RAB18,ATP6V1D,MAGT1,GOLGA7,ELMO1,SNAP29,PML,PGRMC1,IMPDH1,PSAP,PGAM1,IFI16 |
| 4.196e-04 | -7.78 | ubiquitin-dependent ERAD pathway | biological process | GO:0030433 | 65 | 21 | 17256 | 2622 |
SEC61B,TMUB1,ERLIN1,MAN1B1,UBE4B,SYVN1,UBE4A,UBQLN2,EDEM2,DNAJB9,NPLOC4,RNF103,PSMC4,DERL1,ANKZF1,DNAJC10,RNF121,SEL1L,ECPAS,PSMC1,RNF5 |
| 4.209e-04 | -7.77 | TCA Cycle | WikiPathways | WP78 | 17 | 9 | 5312 | 837 |
SDHB,SUCLG1,IDH3A,MDH2,CS,SUCLG2,OGDH,IDH3B,SDHA |
| 4.228e-04 | -7.77 | Cell Cycle Checkpoints | REACTOME pathways | R-HSA-69620 | 201 | 52 | 10287 | 1696 |
MCM10,CLSPN,BABAM1,DBF4,RMI2,ORC1,BLM,CCNB1,PSMD9,RMI1,RPA2,PSMD2,MDM2,PSMD1,BABAM2,PSMA6,CCNA2,MCM5,GTSE1,CDKN1B,ANAPC7,ORC3,RFC3,PSMA8,TOP3A,PSMB7,PSMA1,ANAPC2,CDC6,BRCA1,PKMYT1,CDC23,MCM2,PSMB9,RFC2,PSMB3,PSMC4,RPA1,CDC16,CDC27,RPS27A,PSMD8,PSMD3,H2AFX,YWHAZ,CHEK2,CDK2,UBE2C,YWHAH,CCNB2,PSMC1,ANAPC4 |
| 4.232e-04 | -7.77 | actomyosin contractile ring assembly | biological process | GO:0000915 | 6 | 5 | 17256 | 2622 |
KIF23,RACGAP1,PDCD6IP,ANLN,RTKN |
| 4.232e-04 | -7.77 | assembly of actomyosin apparatus involved in cytokinesis | biological process | GO:0000912 | 6 | 5 | 17256 | 2622 |
KIF23,RACGAP1,PDCD6IP,ANLN,RTKN |
| 4.232e-04 | -7.77 | negative regulation of protein export from nucleus | biological process | GO:0046826 | 6 | 5 | 17256 | 2622 |
CDK5,RANGAP1,TXN,SP100,PARK7 |
| 4.252e-04 | -7.76 | V$ETF_Q6 | MSigDB lists | V$ETF_Q6 | 107 | 30 | 17377 | 2626 |
ASH1L,ZNF496,CELSR2,SLC41A1,DCAF8,MIER1,FAM76A,RRAGC,PPP3CB,ARID1A,USP48,PITHD1,STAM,CDC73,USP21,XPR1,MFN2,HMGN2,DAP3,SUV39H2,CCDC6,UCHL5,SSBP3,YBX1,MAST2,SCYL3,LRP8,CAMK2G,FAF1,ATXN7L2 |
| 4.254e-04 | -7.76 | purine nucleoside monophosphate biosynthetic process | biological process | GO:0009127 | 97 | 28 | 17256 | 2622 |
AMPD2,TGFB1,GALK1,COX5B,LDHA,ADSL,ATP6V0A1,OGDH,ATP5F1B,ADPGK,PKM,ATP5MF,ATP5PF,STOML2,ADSS,GART,ATP5MC3,ATIC,PRPS2,IMPDH1,ATP6V0A2,DHTKD1,GPI,ATP5F1A,CYC1,NIPSNAP2,PGAM1,PFKP |
| 4.254e-04 | -7.76 | purine ribonucleoside monophosphate biosynthetic process | biological process | GO:0009168 | 97 | 28 | 17256 | 2622 |
AMPD2,TGFB1,GALK1,COX5B,LDHA,ADSL,ATP6V0A1,OGDH,ATP5F1B,ADPGK,PKM,ATP5MF,ATP5PF,STOML2,ADSS,GART,ATP5MC3,ATIC,PRPS2,IMPDH1,ATP6V0A2,DHTKD1,GPI,ATP5F1A,CYC1,NIPSNAP2,PGAM1,PFKP |
| 4.262e-04 | -7.76 | GO_TELOMERE_MAINTENANCE_VIA_RECOMBINATION | MSigDB lists | GO_TELOMERE_MAINTENANCE_VIA_RECOMBINATION | 32 | 13 | 17377 | 2626 |
POLA2,RPA2,RAD51C,PCNA,RFC3,POLE,PRIM2,NSMCE2,SMC6,XRCC3,RFC2,RPA1,PRIM1 |
| 4.262e-04 | -7.76 | GO_TRNA_TRANSPORT | MSigDB lists | GO_TRNA_TRANSPORT | 32 | 13 | 17377 | 2626 |
TOMM20,NUP188,NUP210,RAE1,NUP107,NUP54,NUP62,NUP155,NUP153,NUP85,SEH1L,AAAS,NUP205 |
| 4.268e-04 | -7.76 | MAD2L1 (mitotic arrest deficient 2 like 1) | protein interactions | 4085 | 74 | 24 | 17029 | 2761 |
ADAM17,ADAM10,DYNLL1,RAF1,ABCF2,TOR1AIP1,CUL3,ANAPC2,CHMP2B,MACF1,APP,MAD2L2,KEAP1,CCNA2,CDC16,CDC27,PSMD8,E2F4,E2F1,BCL7C,ANAPC7,UBE2C,ANAPC4,TUBB |
| 4.278e-04 | -7.76 | KIM_GERMINAL_CENTER_T_HELPER_UP | MSigDB lists | KIM_GERMINAL_CENTER_T_HELPER_UP | 61 | 20 | 17377 | 2626 |
POU2AF1,PRPF38B,ERMP1,TMBIM4,ACTR3,CREBL2,PAWR,PPP3CB,UTP3,NCKAP1,ETS1,RUFY1,ZNF518A,WRB,MAN1A1,PON2,WDR11,STAT1,FEM1B,ZMAT3 |
| 4.278e-04 | -7.76 | GO_REGULATION_OF_CYTOKINESIS | MSigDB lists | GO_REGULATION_OF_CYTOKINESIS | 61 | 20 | 17377 | 2626 |
PLK3,KIF3B,PKP4,RHOA,KLHL21,CUL3,KIF23,RACGAP1,CDC6,AURKB,BECN1,SH3GLB1,CALM2,PDXP,CCP110,CDC42,PIN1,KIF14,VPS4A,CDC25B |
| 4.278e-04 | -7.76 | FLECHNER_PBL_KIDNEY_TRANSPLANT_REJECTED_VS_OK_UP | MSigDB lists | FLECHNER_PBL_KIDNEY_TRANSPLANT_REJECTED_VS_OK_UP | 61 | 20 | 17377 | 2626 |
SHOC2,TSC22D3,SELPLG,AGPAT1,KLC1,ITM2A,ICAM2,LYN,REEP5,XRCC5,RPA2,TMED10,MTMR4,GOT2,ARHGEF1,MPV17,ANP32E,KPNA2,PDLIM5,FAM208A |
| 4.286e-04 | -7.75 | GSE32164_RESTING_DIFFERENTIATED_VS_CMYC_INHIBITED_MACROPHAGE_DN | MSigDB lists | GSE32164_RESTING_DIFFERENTIATED_VS_CMYC_INHIBITED_MACROPHAGE_DN | 192 | 47 | 17377 | 2626 |
SEPHS2,PKP4,PRKCSH,CDK2AP2,PTTG1,UCK2,FLOT1,BRAP,AGFG1,NANS,BZW2,REPS1,EBP,GSTK1,MED10,NDUFA2,EIF4A3,VMP1,TIMM23,DAD1,H2AFY,SLC38A10,RPL19,SPTSSA,METTL9,F2R,S100A6,LDHB,CSNK1G2,TSPYL4,TUFM,HTATIP2,ITM2A,PSMB3,FAS,MTHFD2,WAS,ATP6V1D,PDCD6,ITGB1,DUSP11,GALNT10,PPP5C,HRAS,SNX14,PDCD4,PFKP |
| 4.286e-04 | -7.75 | GSE17721_CPG_VS_GARDIQUIMOD_2H_BMDC_DN | MSigDB lists | GSE17721_CPG_VS_GARDIQUIMOD_2H_BMDC_DN | 192 | 47 | 17377 | 2626 |
CTDP1,TMED7,NSMCE4A,GGNBP2,H2AFZ,TM9SF4,ZCCHC8,PIGQ,TOR3A,DBF4,USP39,TMED3,COMMD5,RHBDD1,MBD4,RAD23A,RRN3,RAP1A,NOL11,INTS7,ABCD1,GLTP,ALDH18A1,TMEM14C,MYO5A,NIPSNAP1,SRSF11,DEAF1,GUK1,FOPNL,NSDHL,GMFB,MTX1,RHOT1,CBFB,TRIM28,TMEM184C,DERL1,ARNTL,NFIL3,PIAS2,CRCP,ATE1,RNF14,CHMP7,PURA,NUDT3 |
| 4.286e-04 | -7.75 | GSE26030_UNSTIM_VS_RESTIM_TH1_DAY15_POST_POLARIZATION_UP | MSigDB lists | GSE26030_UNSTIM_VS_RESTIM_TH1_DAY15_POST_POLARIZATION_UP | 192 | 47 | 17377 | 2626 |
MAPRE1,GNPNAT1,B4GALT5,SLC39A13,SLC29A1,CDIPT,PIP4K2A,RSAD1,VASP,CBWD2,PPP1R8,MCM5,NUP107,ARL6IP1,BCL2,GEMIN4,MAP3K14,STAT3,FRMD8,HTRA2,SMC4,IFRD1,ACP2,OXR1,LDHA,PIP4K2C,EZR,DNAJC9,C1orf35,MAP4K3,SEPT7,CYFIP2,HLA-B,KPNA4,FBXO28,ETS2,CHD3,MFAP1,MYO18A,ITGB1,ARAP1,YWHAZ,PIEZO1,LTA4H,SNX14,DEF6,AAAS |
| 4.286e-04 | -7.75 | GSE19923_E2A_KO_VS_E2A_AND_HEB_KO_DP_THYMOCYTE_UP | MSigDB lists | GSE19923_E2A_KO_VS_E2A_AND_HEB_KO_DP_THYMOCYTE_UP | 192 | 47 | 17377 | 2626 |
GPR132,SCAMP3,CDT1,CDCA8,UCK1,DNAJB1,PMF1,PDCD7,STMN1,TMEM165,CPNE3,PARK7,MAN1A1,RB1,RAP1A,RAB4A,PRC1,FAM76B,ILKAP,PLK1,SGCE,NXT1,PRIM2,KAT7,WBP2,RRM2,CDC6,AURKB,MCM2,RFC2,KIF11,ANKRD46,ASF1B,NMT2,RPA1,PON2,JAK1,RBL1,CCDC6,RPS14,PITX1,SLAIN1,GAS2,PTDSS1,MYL12B,TUBB,PTOV1 |
| 4.286e-04 | -7.75 | GSE7764_NKCELL_VS_SPLENOCYTE_DN | MSigDB lists | GSE7764_NKCELL_VS_SPLENOCYTE_DN | 192 | 47 | 17377 | 2626 |
MIF4GD,MAX,PLXNC1,GPBP1L1,CDK2AP2,CENPF,KIF23,SLC29A1,PABPC4,IRF4,RB1,TNFAIP8,ATIC,PPP1R8,ARF5,PPME1,BDH1,TTC9C,TECR,GPD1L,MYO5A,SNX8,CLCN3,SHOC2,PPP1R18,MTA2,ERLIN1,TSPAN31,KIAA0930,MKI67,EIF2AK1,CCNF,LY6E,SHCBP1,SYMPK,RBM38,AMZ2,TMEM184C,TXNDC16,SYNCRIP,COX8A,YWHAZ,NANP,CD81,APOL2,RNF139,SVIP |
| 4.286e-04 | -7.75 | GSE7831_UNSTIM_VS_CPG_STIM_PDC_4H_UP | MSigDB lists | GSE7831_UNSTIM_VS_CPG_STIM_PDC_4H_UP | 192 | 47 | 17377 | 2626 |
SLC12A7,DNAJC2,PRKAB1,H2AFZ,GMFG,CXXC1,DHX9,RACGAP1,GYG1,SLC20A1,BZW2,VASP,EIF4A3,SIVA1,ARHGEF1,PRC1,GTSE1,CNN2,CITED2,SLC12A2,ASB6,FTSJ3,EMB,NUDT4,KRAS,CDC6,ZFAND5,PRIM1,XRCC5,MYO1F,ADSS,CHCHD3,PON2,SEPT1,IDE,GALNT2,JAK1,TAB2,TFDP1,ARNTL,MAPK6,PIAS2,CAB39,YWHAZ,HMGB2,SNX14,PFKP |
| 4.286e-04 | -7.75 | GSE36826_WT_VS_IL1R_KO_SKIN_DN | MSigDB lists | GSE36826_WT_VS_IL1R_KO_SKIN_DN | 192 | 47 | 17377 | 2626 |
ZNF207,BCCIP,RHOG,FGFR1OP,CYTIP,CDK2AP2,CSNK2A1,SLC35B1,PARK7,SLC25A37,HNRNPA2B1,IRF4,CDC42,ARF5,DDA1,ZDHHC13,CHTOP,SGCB,S100A6,HNRNPM,CGGBP1,PREB,SRSF10,ORAI2,AATF,HMGN4,MAPKAPK3,SNRPB,LDHA,RNPS1,PSMA1,EMP3,MCL1,DIDO1,EIF4G2,DDX39A,YIF1A,ADSS,DERL1,HNRNPR,TFE3,ACLY,PITPNA,ACTB,H3F3A,LRP8,PFKP |
| 4.296e-04 | -7.75 | APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 | REACTOME pathways | R-HSA-174178 | 73 | 24 | 10287 | 1696 |
PLK1,PSMA8,PTTG1,PSMB7,PSMA1,ANAPC2,AURKB,CDC23,PSMD9,PSMB9,PSMB3,PSMC4,PSMD2,PSMA6,CDC16,PSMD1,CDC27,RPS27A,PSMD8,PSMD3,ANAPC7,UBE2C,PSMC1,ANAPC4 |
| 4.300e-04 | -7.75 | GO_VESICLE_COAT | MSigDB lists | GO_VESICLE_COAT | 44 | 16 | 17377 | 2626 |
TMED7,COPA,COPE,SCYL1,TMED3,SYNRG,COPG2,PICALM,COPB2,NECAP2,SEC31A,SEC24C,AP2B1,AP1S1,CLTB,AP2S1 |
| 4.300e-04 | -7.75 | LUI_THYROID_CANCER_PAX8_PPARG_DN | MSigDB lists | LUI_THYROID_CANCER_PAX8_PPARG_DN | 44 | 16 | 17377 | 2626 |
RPS2,PPT1,TMEM109,TMEM147,DNAJA1,EIF3K,FKBP1A,HINT1,RPL17,PSMD8,ERGIC3,AKR1B1,YWHAZ,SRSF3,FBL,EIF5 |
| 4.300e-04 | -7.75 | WD_REPEATS_1 | prosite domains | PS00678 | 170 | 40 | 12060 | 1670 |
WSB2,CORO7,CDC40,COPA,TRAF7,RAE1,POC1A,STRN4,WDR5,GNB2,WDR48,DTL,UTP18,FBXW2,TAF5L,CORO1A,STRAP,CSTF1,WDR41,MLST8,PRPF19,WDR1,WDR18,SMU1,UTP15,WDHD1,WDR82,EML4,GEMIN5,WDR11,BRWD1,SCAP,CORO1C,TBL3,WDR59,WDR7,PRPF4,RBBP4,BRWD3,AAAS |
| 4.315e-04 | -7.75 | Oocyte meiosis | KEGG pathways | ko04114 | 120 | 34 | 7161 | 1149 |
RPS6KA1,PTTG1,CUL1,PPP3CB,CCNB1,PRKACA,MAD2L2,FBXO5,CALM2,SMC3,ADCY9,ANAPC7,CAMK2G,ADCY7,PLK1,PPP3CA,RBX1,ANAPC2,PKMYT1,CDC23,MAPK3,PPP2CA,CDC16,PPP2R5A,CDC27,PPP3R1,YWHAZ,CDK2,YWHAH,CCNB2,MAPK1,CPEB2,ESPL1,ANAPC4 |
| 4.315e-04 | -7.75 | Oocyte meiosis | KEGG pathways | hsa04114 | 120 | 34 | 7161 | 1149 |
RPS6KA1,PTTG1,CUL1,PPP3CB,CCNB1,PRKACA,MAD2L2,FBXO5,CALM2,SMC3,ADCY9,ANAPC7,CAMK2G,ADCY7,PLK1,PPP3CA,RBX1,ANAPC2,PKMYT1,CDC23,MAPK3,PPP2CA,CDC16,PPP2R5A,CDC27,PPP3R1,YWHAZ,CDK2,YWHAH,CCNB2,MAPK1,CPEB2,ESPL1,ANAPC4 |
| 4.324e-04 | -7.75 | MODULE_253 | MSigDB lists | MODULE_253 | 21 | 10 | 17377 | 2626 |
KIF3B,MAPRE1,DYNLL1,KIF14,DCTN2,KIF23,KIF2C,KIF11,STMN1,DYNC1LI2 |
| 4.324e-04 | -7.75 | RAHMAN_TP53_TARGETS_PHOSPHORYLATED | MSigDB lists | RAHMAN_TP53_TARGETS_PHOSPHORYLATED | 21 | 10 | 17377 | 2626 |
PRDX3,IDH3A,ACTB,RUVBL2,PDIA6,PCBP1,PGAM1,PPA1,PARK7,VPS29 |
| 4.324e-04 | -7.75 | GO_BASAL_TRANSCRIPTION_MACHINERY_BINDING | MSigDB lists | GO_BASAL_TRANSCRIPTION_MACHINERY_BINDING | 21 | 10 | 17377 | 2626 |
PAF1,ERCC1,ZNHIT6,ZNF326,ELP4,CTR9,RUVBL2,FBL,CDC73,RPRD1B |
| 4.340e-04 | -7.74 | SENESE_HDAC3_TARGETS_UP | MSigDB lists | SENESE_HDAC3_TARGETS_UP | 464 | 97 | 17377 | 2626 |
ASH1L,FAM208B,ABCA3,COPA,NF1,ADAM10,SF3B1,BCL2L1,MAPK14,SLC25A37,CREM,PAPOLA,CALM2,DST,AHCTF1,RAB35,IL6ST,ATP13A3,SEPT11,RNF19A,LMAN1,GM2A,MOSPD1,USP34,BIRC3,APH1A,BTG2,TAOK1,EZR,MCL1,BICD2,OGDH,KDM1B,STX16,CBFB,GFER,DPYSL3,SUPT16H,ANKRD10,ZNF317,HSPA4,JAK1,SEC61A1,DUS3L,UEVLD,ITGB1,CANT1,AP1S1,USP53,ZMAT3,DDX42,NXT2,TM9SF4,RHOC,TRIO,DHX9,FLOT1,B4GALT1,AKT1S1,GGA2,SCYL2,VPS25,TFRC,ZNF92,MAN1A1,RB1,MEX3C,ITGB8,INPP5A,ARL6IP1,PTPN11,PIK3IP1,TMED2,UBE2QL1,RPAP3,PPP3CA,TNFAIP3,GALC,USP10,FXR1,KLF6,ANKRD46,RHOB,FAS,EPRS,SCARB2,CDC27,ETS2,SNAP23,USP32,SLC16A1,FAM126A,YWHAZ,CPEB2,TOB1,IFI16,ESYT2 |
| 4.343e-04 | -7.74 | negative regulation of cellular metabolic process | biological process | GO:0031324 | 2547 | 444 | 17256 | 2622 |
FGFR1OP,TXN,ZNF496,MAX,H2AFZ,TSC2,KDM4A,TSC22D3,XIAP,YTHDF3,CCNB1,UBE2I,PPP1R16B,RBM4,RIC1,PARK7,CALM2,CDK5,CDKN2C,PA2G4,CIPC,PARPBP,SRSF4,TRA2B,CRY2,FNIP2,SMARCE1,DNMT1,SENP1,SRSF10,BAK1,PLK3,ERCC1,KLF10,AATF,GABPA,PBK,EHMT1,DDX20,MCL1,AURKB,EIF3A,PLEKHF2,DOT1L,BRMS1,HHEX,SMAD2,RPS27A,RPS14,LIMK1,AXIN1,PRDX5,OGT,TFDP2,ARRB2,HDAC2,PDCD4,SVIP,HSPH1,GMFG,PHF23,PRKAA1,DHX9,EIF2AK4,PARN,PSEN1,METTL3,VPS25,CDC73,CNOT3,CFLAR,CD59,TFAP4,FKBP1A,SMC3,MEX3C,KLF16,HDAC7,FBXO7,PHF14,MSH2,DAPK1,PIK3IP1,MVP,GNAI2,LPCAT1,TNRC18,PABPC1,TERF2,SOCS5,RBM42,ETV3,FOXK1,ZMYND11,MTA2,GTPBP4,ITM2A,BCLAF1,ARID1A,CBFA2T2,FXR1,KDM3A,PHF6,XRCC5,EPRS,PFDN5,GOLGA2,ETS2,DUSP3,CSK,RBMX,QARS,CABIN1,YY1,ZNF830,CDK2,RNF139,CDKN2A,EGLN1,ZNF296,PPP1R37,DNMT3A,GGNBP2,RPS6KA1,UBR2,CAST,SUZ12,RAF1,PTTG1,MAGED1,WDTC1,RCOR3,APP,PAIP2,TERF2IP,SPINDOC,APLP2,SHC1,SP100,MTA1,TBC1D14,UCHL5,SOCS6,CDKN1B,RBM15,ATF2,GPD1L,CGGBP1,PDCL3,RNF169,SAP30,ANKLE2,ERF,EID1,DRAP1,RNPS1,CUL3,CIRBP,PKMYT1,DNAJA1,H2AFV,TRIM28,SOCS7,PPP2CA,CHCHD3,ZNF282,CHMP4A,PPP2R5A,CORO1C,HIPK2,H2AFX,STAT1,BEND3,PPP5C,LRP8,POLQ,NCOR2,DEPDC1,SRSF6,MECP2,TCF3,SECISBP2,AKT1S1,BLM,HMG20A,FOXO3,MAD2L2,WWP2,SUV39H2,PTEN,PPP1R8,AXIN2,CITED2,CNOT6L,CREB1,NCOA2,MSH6,TSHZ1,PDPK1,PPP3CA,TNFAIP3,ILF3,ZP3,PICALM,CBX3,SH3BP5,GPS2,ZHX1,PRDX3,PITX1,LRPPRC,PML,KHSRP,PPP1R11,DDX5,HMGB2,PARP10,IGBP1,CPEB2,PURA,RORB,ZBED3,THOC1,NF1,TRIM11,PPP1R15B,FAM129A,ENSA,CSNK2A1,SIRT2,UBQLN2,BECN1,MAPK14,BIRC2,CREM,PRNP,CYREN,GLIS2,EIF4A3,ZNF639,METTL14,JAZF1,ETV6,PIK3R2,NOC2L,PPP1R12C,OGG1,ARID4A,CCAR1,PTPRK,RYBP,PLK1,SP3,DEAF1,LARS,PBXIP1,NCK1,BAZ2A,VHL,RIOX2,GMFB,EZR,CDC6,LRP5,BRCA1,SOX4,OPTN,PAF1,EIF4ENIF1,TONSL,SOCS4,ZNF268,CHEK2,CLU,ROCK1,DVL1,CLN3,BEND6,RPS26,POT1,ZNF564,UBE2D3,ZCCHC9,PPP1R2,PPP1R12A,PHB2,CENPF,UBXN1,CIB1,CTCF,TIA1,MEF2A,DNAJB1,THRAP3,RGS2,TTF1,LYAR,RB1,MLX,NFATC3,TIGAR,MBD2,ZNF746,ARL6IP1,CTR9,TIMELESS,BCL2,MDFIC,YBX1,MCPH1,ZNF189,CREG1,ERLIN1,CIC,OXR1,LDB1,GBA,EIF2AK1,RTF1,EIF4G2,DAPK3,ISG15,ZNF174,MASTL,TSC1,MBIP,SYNCRIP,ORMDL2,KLHL15,NFIL3,SIAH2,NUP62,CTSA,ZFP90,RUVBL2,SNRNP70,TOB1,N4BP2L2,USP7,MBD1,ASH1L,FEZ2,MPHOSPH8,FOXM1,DYNLL1,SMARCA4,IRF3,LYN,DUSP22,MXD1,PAIP1,RPL11,HNRNPA2B1,SAP130,ZBTB21,MDM2,TNFAIP8,PIN1,PPME1,TARDBP,STRAP,CTDSP2,HTRA2,RLIM,MOSPD1,CHP1,SNX25,PPIF,UBQLN4,TIMP2,BIRC3,FAM172A,ZNF500,BTG2,PCGF6,ATXN1,NFATC2,MBD3,USP36,DNAJC10,IDE,ATP1A1,TAB2,RBL1,HNRNPR,MAFK,STAT6,STK38,GADD45B,ARNTL,DNAJC17,CHMP4B,H3F3A,SMAD4,CBX4,PARD3,MIF,BCL2L12,DNAJC2,UNK,TRIP12,DAP,AGO2,ARID5A,PAWR,NKRF,MXD4,FBXO5,PTPN2,KMT5A,DUS2,H2AFY,BRD7,STAT3,RNF5,RBM15B,TGFB1,SAMD4B,PPP1R9B,RHOA,PSPC1,ZNF202,PRKDC,HELB,BTAF1,PRKAR1B,RFFL,RCOR1,WDR81,PRMT2,MEN1,HSPA1B,CNOT9,LEMD2,UPF1,PLAA,BIRC5,E2F1,GLG1,RBPJ,NR2F2,TERF1,HIPK3,IFI16 |
| 4.354e-04 | -7.74 | Znf_PHD | interpro domains | IPR001965 | 89 | 26 | 18492 | 2768 |
PHF10,ASH1L,KMT2E,BAZ2A,PHF23,KDM4A,SHPRH,PHRF1,CXXC1,ZMYND11,NSD3,DIDO1,KMT2C,TCF19,TRIM28,PHF6,SP100,BRPF3,KDM2A,CHD3,PHF14,UHRF2,KMT2B,BAZ1B,INTS12,FBXL19 |
| 4.358e-04 | -7.74 | upper_aerodigestive_tract-mouth-carcinoma-adenoid_cystic_carcinoma | COSMIC cancer mutations | upper_aerodigestive_tract-mouth-carcinoma-adenoid_cystic_carcinoma | 386 | 82 | 17385 | 2587 |
FGFR1OP,RPS6KA1,RAF1,CSNK2A1,PRKACA,DUSP22,MAPK14,CPNE3,CDK5,ABL2,CRKL,PDK2,PIK3R2,TCEA1,TFG,ILKAP,SCYL3,SRPK2,SRP72,AKT2,GOPC,PBK,MAP4K4,PFKFB3,GALK2,AURKB,SOX4,PRKRA,PRPSAP1,MAP3K4,JAK1,CLK3,STK38,HIPK2,FASTK,AXIN1,STK11,CHEK2,PDXK,MAPK1,PFKP,SEPHS2,NACA,GNE,TRIO,DBF4,CERK,CDK13,IP6K2,PMVK,CSNK1A1,FOXO3,GTF2F1,PIP5K1C,FGFR3,RB1,DAPK1,PTPN11,PIKFYVE,ALDH18A1,CAMK2G,CSNK1G3,AGGF1,GUK1,RB1CC1,NEK7,PIP4K2C,EIF2AK1,MAP4K3,MAP2K2,DAPK3,MAPK3,PCM1,CCDC6,DCK,MAPK6,FN3KRP,NUP62,MAP3K5,PDLIM5,CDK2,RPS6KC1 |
| 4.358e-04 | -7.74 | salivary_gland-carcinoma | COSMIC cancer mutations | salivary_gland-carcinoma | 386 | 82 | 17385 | 2587 |
FGFR1OP,RPS6KA1,RAF1,CSNK2A1,PRKACA,DUSP22,MAPK14,CPNE3,CDK5,ABL2,CRKL,PDK2,PIK3R2,TCEA1,TFG,ILKAP,SCYL3,SRPK2,SRP72,AKT2,GOPC,PBK,MAP4K4,PFKFB3,GALK2,AURKB,SOX4,PRKRA,PRPSAP1,MAP3K4,JAK1,CLK3,STK38,HIPK2,FASTK,AXIN1,STK11,CHEK2,PDXK,MAPK1,PFKP,SEPHS2,NACA,GNE,TRIO,DBF4,CERK,CDK13,IP6K2,PMVK,CSNK1A1,FOXO3,GTF2F1,PIP5K1C,FGFR3,RB1,DAPK1,PTPN11,PIKFYVE,ALDH18A1,CAMK2G,CSNK1G3,AGGF1,GUK1,RB1CC1,NEK7,PIP4K2C,EIF2AK1,MAP4K3,MAP2K2,DAPK3,MAPK3,PCM1,CCDC6,DCK,MAPK6,FN3KRP,NUP62,MAP3K5,PDLIM5,CDK2,RPS6KC1 |
| 4.358e-04 | -7.74 | upper_aerodigestive_tract-head_neck-carcinoma-adenoid_cystic_carcinoma | COSMIC cancer mutations | upper_aerodigestive_tract-head_neck-carcinoma-adenoid_cystic_carcinoma | 386 | 82 | 17385 | 2587 |
FGFR1OP,RPS6KA1,RAF1,CSNK2A1,PRKACA,DUSP22,MAPK14,CPNE3,CDK5,ABL2,CRKL,PDK2,PIK3R2,TCEA1,TFG,ILKAP,SCYL3,SRPK2,SRP72,AKT2,GOPC,PBK,MAP4K4,PFKFB3,GALK2,AURKB,SOX4,PRKRA,PRPSAP1,MAP3K4,JAK1,CLK3,STK38,HIPK2,FASTK,AXIN1,STK11,CHEK2,PDXK,MAPK1,PFKP,SEPHS2,NACA,GNE,TRIO,DBF4,CERK,CDK13,IP6K2,PMVK,CSNK1A1,FOXO3,GTF2F1,PIP5K1C,FGFR3,RB1,DAPK1,PTPN11,PIKFYVE,ALDH18A1,CAMK2G,CSNK1G3,AGGF1,GUK1,RB1CC1,NEK7,PIP4K2C,EIF2AK1,MAP4K3,MAP2K2,DAPK3,MAPK3,PCM1,CCDC6,DCK,MAPK6,FN3KRP,NUP62,MAP3K5,PDLIM5,CDK2,RPS6KC1 |
| 4.358e-04 | -7.74 | upper_aerodigestive_tract-lymph_node-carcinoma-adenoid_cystic_carcinoma | COSMIC cancer mutations | upper_aerodigestive_tract-lymph_node-carcinoma-adenoid_cystic_carcinoma | 386 | 82 | 17385 | 2587 |
FGFR1OP,RPS6KA1,RAF1,CSNK2A1,PRKACA,DUSP22,MAPK14,CPNE3,CDK5,ABL2,CRKL,PDK2,PIK3R2,TCEA1,TFG,ILKAP,SCYL3,SRPK2,SRP72,AKT2,GOPC,PBK,MAP4K4,PFKFB3,GALK2,AURKB,SOX4,PRKRA,PRPSAP1,MAP3K4,JAK1,CLK3,STK38,HIPK2,FASTK,AXIN1,STK11,CHEK2,PDXK,MAPK1,PFKP,SEPHS2,NACA,GNE,TRIO,DBF4,CERK,CDK13,IP6K2,PMVK,CSNK1A1,FOXO3,GTF2F1,PIP5K1C,FGFR3,RB1,DAPK1,PTPN11,PIKFYVE,ALDH18A1,CAMK2G,CSNK1G3,AGGF1,GUK1,RB1CC1,NEK7,PIP4K2C,EIF2AK1,MAP4K3,MAP2K2,DAPK3,MAPK3,PCM1,CCDC6,DCK,MAPK6,FN3KRP,NUP62,MAP3K5,PDLIM5,CDK2,RPS6KC1 |
| 4.358e-04 | -7.74 | upper_aerodigestive_tract-carcinoma | COSMIC cancer mutations | upper_aerodigestive_tract-carcinoma | 386 | 82 | 17385 | 2587 |
FGFR1OP,RPS6KA1,RAF1,CSNK2A1,PRKACA,DUSP22,MAPK14,CPNE3,CDK5,ABL2,CRKL,PDK2,PIK3R2,TCEA1,TFG,ILKAP,SCYL3,SRPK2,SRP72,AKT2,GOPC,PBK,MAP4K4,PFKFB3,GALK2,AURKB,SOX4,PRKRA,PRPSAP1,MAP3K4,JAK1,CLK3,STK38,HIPK2,FASTK,AXIN1,STK11,CHEK2,PDXK,MAPK1,PFKP,SEPHS2,NACA,GNE,TRIO,DBF4,CERK,CDK13,IP6K2,PMVK,CSNK1A1,FOXO3,GTF2F1,PIP5K1C,FGFR3,RB1,DAPK1,PTPN11,PIKFYVE,ALDH18A1,CAMK2G,CSNK1G3,AGGF1,GUK1,RB1CC1,NEK7,PIP4K2C,EIF2AK1,MAP4K3,MAP2K2,DAPK3,MAPK3,PCM1,CCDC6,DCK,MAPK6,FN3KRP,NUP62,MAP3K5,PDLIM5,CDK2,RPS6KC1 |
| 4.371e-04 | -7.74 | Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) | REACTOME pathways | R-HSA-975956 | 99 | 30 | 10287 | 1696 |
RPS15,RPL29,RPS2,RPL35,RPLP2,GSPT2,RPS10,RPL6,RPL38,RPL8,RPL15,RPS24,RPL27A,RPS9,RPSA,RPL11,RPL36,RPL23A,RPL37,UPF1,RPL32,RPS27A,RPL17,RPS14,RPLP1,RPL19,FAU,RPS26,RPL22L1,PABPC1 |
| 4.372e-04 | -7.74 | GSE32423_IL7_VS_IL7_IL4_MEMORY_CD8_TCELL_UP | MSigDB lists | GSE32423_IL7_VS_IL7_IL4_MEMORY_CD8_TCELL_UP | 187 | 46 | 17377 | 2626 |
ATXN3,WDYHV1,ANKH,TMX4,TRAK1,CSNK2A1,MYH9,CDC42SE2,RAB6A,GGA2,WDR5,MAP1LC3B,RNF103,GART,UBE2Q2,YBX1,CDC25B,GLE1,C12orf75,TPCN1,TMBIM1,SMC4,ABCC5,PTPRK,RPRD1A,RB1CC1,EMB,RDH10,PSMB7,HNRNPF,SRSF5,KDM1B,PON2,ATP6V1D,DSN1,UAP1,OAZ2,CAPN7,APPL2,DTX4,AEN,YWHAZ,ACADM,PIEZO1,GLCCI1,RHEBL1 |
| 4.372e-04 | -7.74 | GSE25087_FETAL_VS_ADULT_TREG_UP | MSigDB lists | GSE25087_FETAL_VS_ADULT_TREG_UP | 187 | 46 | 17377 | 2626 |
LUZP1,AGRN,RHOC,TRIO,STARD7,C5orf30,PXMP2,SLC29A1,POMP,NOTCH2,EPHX2,SLC25A43,TFRC,ATPAF1,KIAA1147,BANF1,UBA5,TIMELESS,BRD7,TOP1MT,PDIA6,LRRC59,PTPRK,PPIF,CYFIP1,RHOA,DRAP1,GLO1,KIAA1586,BRCA1,MCM2,TXNL4A,EIF4G2,RPA1,MAN2A2,SLC19A1,ACYP1,PRDX3,MRPL27,STAT1,SIAH2,NUP62,UQCRH,YY1,MRPL13,CABLES1 |
| 4.372e-04 | -7.74 | GSE22935_UNSTIM_VS_12H_MBOVIS_BCG_STIM_MACROPHAGE_DN | MSigDB lists | GSE22935_UNSTIM_VS_12H_MBOVIS_BCG_STIM_MACROPHAGE_DN | 187 | 46 | 17377 | 2626 |
CTDP1,LZTR1,C19orf53,HABP4,COX4I1,NUF2,ATG2B,THRAP3,GGA2,XPO7,C2orf49,TWF2,SDHA,SSBP3,XPA,EI24,FAM89B,AKR1B1,RPL19,GLE1,RNF26,NUP85,PREB,SRPK2,SEC61B,FAM49B,ZMYM5,SUGP2,SLC16A7,SEPT8,WBP1,RPL27A,FANCE,POLR2A,RDH11,TFEB,RPL36,RPA1,EPB41,TMEM41A,CDKN2AIPNL,ATP6V1D,PGRMC1,ZFP90,COPS6,TMEM33 |
| 4.372e-04 | -7.74 | GSE3982_NEUTROPHIL_VS_EFF_MEMORY_CD4_TCELL_UP | MSigDB lists | GSE3982_NEUTROPHIL_VS_EFF_MEMORY_CD4_TCELL_UP | 187 | 46 | 17377 | 2626 |
CYTIP,FAM53C,RAF1,RRAGC,HAUS4,MYO9B,ZNF267,SLC25A44,AP3S1,RCOR3,FOXO3,CHD1,GIT2,MXD1,HLA-A,PHC2,RALB,ZCCHC2,ZNF200,FAM89B,OSTF1,CYB5R1,CLTB,CDK12,PLK3,FTL,ZDHHC18,MKLN1,RAB7A,NQO2,MTMR6,PFKFB3,MCL1,BRCA1,CAPZA2,SRSF5,ISG15,RHBDF2,UPF1,CSK,OSBPL8,IMPDH1,CANT1,ATP6V0C,NCOA1,MAPK1 |
| 4.372e-04 | -7.74 | GSE43955_1H_VS_10H_ACT_CD4_TCELL_UP | MSigDB lists | GSE43955_1H_VS_10H_ACT_CD4_TCELL_UP | 187 | 46 | 17377 | 2626 |
PRKAB1,VTI1A,EZH1,CSNK1A1,PARK7,WWP2,VAV1,ATP6V0B,RRN3,C18orf32,NDUFA2,AP3S2,TANK,FAM89B,FEM1B,SLC35C2,HDHD2,PCBP2,ALDH9A1,ATP6V1G1,SRPK2,FYTTD1,CYTH1,ZFP64,ELL2,ERF,NSUN2,VDAC2,NUSAP1,DCUN1D5,NUTF2,RAB1A,ARPC1A,RAB5B,PSMB3,EIF3A,DAPK3,PLD3,PDRG1,SNAP23,PSMD3,TBPL1,HMGB2,PREPL,CD81,HIPK3 |
| 4.372e-04 | -7.74 | GSE41867_DAY8_EFFECTOR_VS_DAY30_MEMORY_CD8_TCELL_LCMV_ARMSTRONG_DN | MSigDB lists | GSE41867_DAY8_EFFECTOR_VS_DAY30_MEMORY_CD8_TCELL_LCMV_ARMSTRONG_DN | 187 | 46 | 17377 | 2626 |
SART1,NCOR2,SRSF6,TOR3A,TATDN3,DLGAP4,MRPS26,MYH9,RRAGC,GTF3A,NIT2,MYO9B,NOTCH2,IL21R,LYN,PITHD1,POFUT1,PIP5K1C,VASP,RBM34,ZDHHC13,CEP63,MRPL21,MRPL11,MGAT5,NAGPA,NTPCR,FAM49B,FAM172A,LDB1,ILF3,ZBED5,PRPF3,AMDHD2,STK17B,TSR2,PLEKHF2,RHBDF2,TFEB,FAS,SLC19A1,KEAP1,GRIPAP1,CDCA7L,NRM,TCOF1 |
| 4.372e-04 | -7.74 | GSE17186_BLOOD_VS_CORD_BLOOD_CD21LOW_TRANSITIONAL_BCELL_UP | MSigDB lists | GSE17186_BLOOD_VS_CORD_BLOOD_CD21LOW_TRANSITIONAL_BCELL_UP | 187 | 46 | 17377 | 2626 |
UBE2D3,HECA,ADD1,CAST,ANKH,CCM2,AP3M2,MYH9,SLC20A1,IL21R,ITGB5,RAPGEF6,KIAA1147,MAT2B,GOLM1,NFATC3,PDCD10,ADD3,HDAC7,RCSD1,TECR,SMC4,CYTH1,NCK1,HELB,LDB1,RPS10,HSDL1,EZR,LRRC8A,EMP3,RTF1,ICAM2,RBM38,UBTF,MTMR3,GALNT2,PPP2R5A,L3MBTL3,FAM3C,WDR7,RNF38,DUSP11,CBX4,DEF6,PDCD4 |
| 4.372e-04 | -7.74 | GSE19888_NO_PRETREAT_VS_ADENOSINE_A3R_INHIBITOR_PRETREATED_MAST_CELL_TCELL_MEMBRANES_ACT_UP | MSigDB lists | GSE19888_NO_PRETREAT_VS_ADENOSINE_A3R_INHIBITOR_PRETREATED_MAST_CELL_TCELL_MEMBRANES_ACT_UP | 187 | 46 | 17377 | 2626 |
PPP1R37,DDX47,PKP4,HNRNPAB,DNAJB2,SUZ12,PITHD1,PARK7,NUP205,USP5,PHC2,UTP18,CS,CHTOP,CYFIP1,MND1,SGCE,TUFM,NLN,DCTD,ABHD11,FAM133B,MPG,COMMD4,PDE3B,GOSR1,APPL1,USP21,MTR,NSA2,FNTA,GOLGA7,SLC38A7,DGCR8,NSMCE2,CTBS,MRPL27,DTX4,SLC16A1,ST3GAL2,XRCC3,RRS1,TATDN1,CLN3,TSPAN5,SSRP1 |
| 4.394e-04 | -7.73 | positive regulation of DNA repair | biological process | GO:0045739 | 48 | 17 | 17256 | 2622 |
FOXM1,EYA1,BABAM1,DHX9,MRNIP,BRCA1,TRIM28,BABAM2,PCNA,TIGAR,CEBPG,H2AFX,TIMELESS,SLF1,EYA2,SLF2,SPIDR |
| 4.394e-04 | -7.73 | regulation of mitotic metaphase/anaphase transition | biological process | GO:0030071 | 48 | 17 | 17256 | 2622 |
PLK1,ZNF207,CDT1,CENPF,CUL3,CDC6,CCNB1,CDC23,MAD2L2,RB1,NEK6,NSMCE2,XRCC3,GEN1,UBE2C,ESPL1,ANAPC4 |
| 4.397e-04 | -7.73 | TBP (TATA-box binding protein) | protein interactions | 6908 | 175 | 46 | 17029 | 2761 |
POU3F2,TCF12,ZNF76,MAX,CXXC1,NACA,DHX9,MEF2A,UBE2I,ETS1,SNAPC4,GNB2,CREM,GTF2F1,RB1,SUB1,RRN3,MDM2,CD3EAP,HUWE1,MBD2,ICE2,TCEA1,CITED2,ERCC1,CREG1,BTAF1,DRAP1,USP10,EDF1,MCM2,POLR2A,TAF2,UBTF,TRAM2,BRD2,GOLGA2,E2F1,TBPL1,DDX5,RBPJ,TAF12,RUVBL2,NCOA1,WDR62,TAF6 |
| 4.405e-04 | -7.73 | nuclear replisome | cellular component | GO:0043601 | 25 | 11 | 18223 | 2701 |
POLA2,RPA2,PRIM2,TONSL,HELB,XPA,PURA,PRIM1,CDC5L,RPA1,PRPF19 |
| 4.407e-04 | -7.73 | GCM_RAD21 | MSigDB lists | GCM_RAD21 | 36 | 14 | 17377 | 2626 |
HMGN1,NAP1L1,SUMO2,SRSF4,LRPPRC,CTCF,TRA2B,BCLAF1,DDX5,YWHAZ,TCEA1,EIF4G2,PCBP1,HNRNPM |
| 4.407e-04 | -7.73 | GCM_ANP32B | MSigDB lists | GCM_ANP32B | 36 | 14 | 17377 | 2626 |
HMGN1,NAP1L1,H2AFZ,DUT,MCM5,DRAP1,SNRPB,NACA,FXR1,TRIM28,SNRPA,RPL11,HMGN2,EBP |
| 4.407e-04 | -7.73 | SHIN_B_CELL_LYMPHOMA_CLUSTER_8 | MSigDB lists | SHIN_B_CELL_LYMPHOMA_CLUSTER_8 | 36 | 14 | 17377 | 2626 |
GNAS,MAFK,STAT1,H2AFX,MFNG,SOX4,CCNB1,CDK2,PSEN1,CCNB2,LYN,IL21R,MAPK3,FAS |
| 4.407e-04 | -7.73 | REACTOME_GLYCOSPHINGOLIPID_METABOLISM | MSigDB lists | REACTOME_GLYCOSPHINGOLIPID_METABOLISM | 36 | 14 | 17377 | 2626 |
GALC,HEXB,CERK,GBA,ASAH1,SUMF1,SUMF2,CTSA,SMPD4,PSAP,HEXA,ARSK,GM2A,NEU1 |
| 4.407e-04 | -7.73 | REACTOME_TRIGLYCERIDE_BIOSYNTHESIS | MSigDB lists | REACTOME_TRIGLYCERIDE_BIOSYNTHESIS | 36 | 14 | 17377 | 2626 |
ACSL5,ELOVL5,AGPAT2,LPIN2,ACSL3,LPCAT4,ACLY,AGPAT1,AGPAT3,TECR,LCLAT1,GPD1L,LPCAT1,SLC25A1 |
| 4.407e-04 | -7.73 | MODULE_484 | MSigDB lists | MODULE_484 | 40 | 15 | 17377 | 2626 |
RPL37,DECR1,RPLP2,HDAC7,ARHGEF1,ARHGDIB,CORO1A,SYVN1,CYFIP2,TAZ,SPPL2B,RPS9,LDHB,SOCS7,HP1BP3 |
| 4.407e-04 | -7.73 | CHANDRAN_METASTASIS_TOP50_DN | MSigDB lists | CHANDRAN_METASTASIS_TOP50_DN | 40 | 15 | 17377 | 2626 |
MAGED2,IER2,TOMM20,WAS,AGGF1,PBXIP1,PHB2,NT5DC1,WNT5B,STAT6,CIRBP,TM9SF3,CHMP4B,ARL5A,ANXA11 |
| 4.407e-04 | -7.73 | BURTON_ADIPOGENESIS_PEAK_AT_16HR | MSigDB lists | BURTON_ADIPOGENESIS_PEAK_AT_16HR | 40 | 15 | 17377 | 2626 |
POLA2,MCM5,EMB,DUT,ABCF2,RRM2,HMGB2,CDC6,SMC2,NAP1L4,DNMT1,ABCF1,MSH6,IFI16,ASF1B |
| 4.407e-04 | -7.73 | TINF2 (TERF1 interacting nuclear factor 2) | protein interactions | 26277 | 114 | 33 | 17029 | 2761 |
PPP1R2,TRIP10,KCTD17,SIRT2,SRRT,CPNE3,FERMT3,TERF2IP,ANXA5,GCC1,PACS2,EEF1D,TERF2,NUDC,PRKDC,LDHA,PKM,NCDN,RPSA,PEX5,CLK3,APPL2,PPP3R1,SIAH2,ACTB,FKBP5,DHFR2,PPP6R3,LTA4H,TERF1,POT1,TUBB,PFKP |
| 4.407e-04 | -7.73 | WDR77 (WD repeat domain 77) | protein interactions | 79084 | 114 | 33 | 17029 | 2761 |
ZNF207,CTDP1,CYLD,THOC1,CXXC1,SUZ12,SMARCA4,SNRPD3,UBE2Q2,CTNNBL1,EIF4A3,PPP1R8,MBD2,H2AFY,AQR,CHTOP,PCBP2,HNRNPM,COPS8,CCT2,SNRPB,DCAF8,CUL3,CIRBP,GAR1,CLNS1A,HGS,LSM6,PQBP1,SMAD1,SMURF1,ARRB2,CDK2 |
| 4.412e-04 | -7.73 | GO_TRANSCRIPTION_ELONGATION_FROM_RNA_POLYMERASE_II_PROMOTER | MSigDB lists | GO_TRANSCRIPTION_ELONGATION_FROM_RNA_POLYMERASE_II_PROMOTER | 70 | 22 | 17377 | 2626 |
CTDP1,POLR2I,POLR2G,POLR2L,ELL2,POLR2K,POLR2D,ELP4,RTF1,CDC73,POLR2A,GTF2F1,SUPT16H,PAF1,TAF2,CCNK,POLR2J,TAF12,TCEA1,GTF2H2,TAF6,SSRP1 |
| 4.413e-04 | -7.73 | E2F transcription factor network | Pathway Interaction DB | e2f_pathway | 72 | 26 | 2226 | 426 |
TK1,KAT2A,MYBL2,RRM1,E2F3,RRM2,MCL1,CDC6,BRCA1,ORC1,TRIM28,CDKN2C,RB1,CCNA2,RBL1,TFE3,E2F4,TFDP1,E2F1,CDKN1B,RBBP4,YY1,TFDP2,CDK2,E2F2,RYBP |
| 4.420e-04 | -7.72 | Metabolic pathways | KEGG pathways | hsa01100 | 1256 | 242 | 7161 | 1149 |
ADA2,SRM,POLA2,COX15,PIGM,PPCS,NDUFB6,GNPDA1,PIGQ,UQCR10,HEXB,MOGS,MCCC1,AGPAT1,GLUD1,GYG1,NANS,CDIPT,OAT,ATP5PF,POLR3K,BCAT2,GOT2,IMPAD1,PPCDC,HADHB,MECR,AKR1B1,SUCLG2,UPRT,NDUFB9,ZNRD1,DNMT1,MGAT5,DPM1,LAP3,RRM2,GALNT7,ODC1,PRIM1,MAN2A2,ALG3,AGPAT2,STT3A,NAGLU,QRSL1,MLYCD,COX5A,UQCRH,ST3GAL2,ATP6V0C,GALNT10,DHFR2,CHPT1,CHPF2,ATP6V0E1,PFKP,B4GALT2,SEPHS2,NDUFV2,COX5B,PIGN,MUT,POLR2K,ADO,RRM1,ASAH1,B4GALT1,NDUFA4,COX4I1,CYCS,B4GALT4,EPHX2,NDUFS7,NDUFS4,CHKA,GNS,PDXP,C1GALT1,RPN1,INPP5A,ATIC,DAD1,BDH1,CTPS1,ATP6V0A2,AHCY,PCYT2,CYC1,ACAD8,ALDH18A1,LPCAT1,ATP6V0D1,ALDH9A1,FDFT1,NTPCR,POLR2I,PIGT,PRIM2,TSTA3,PGS1,NSDHL,MAN1B1,AMD1,ACSL3,RDH10,GBA,DCTD,PKM,MTR,TWISTNB,RDH11,PI4K2A,ADSS,SDHB,EPRS,MTHFD2,GALNT2,POLR2J,UAP1,QARS,DCK,PRPS2,ACLY,LPCAT4,MDH1,ATP5F1A,GPI,SMPD4,NANP,HEXA,PTDSS1,NDUFA5,DNMT3A,UGP2,SUCLG1,MDH2,UROD,UCK2,UCK1,RXYLT1,CHKB,ADPGK,ATP6V1B2,GGPS1,LCLAT1,SDHA,EXT2,FLAD1,ATP6V0B,MTMR4,DUT,LPIN2,CS,RPN2,TALDO1,MINPP1,AHCYL1,ATP6V1G1,ACSL5,POLR2L,POLR2G,PPT1,IDH3A,CPOX,POLR2D,MTMR6,ATP6V0A1,OGDH,NDUFA7,NDUFB1,POLG2,PDHX,MAT2A,ALDH3B1,PON2,DDOST,CERS6,NT5C3B,NDUFA11,MBOAT1,PDXK,B4GALT3,LTA4H,GALK1,NADSYN1,CMAS,GCLM,CDS2,NDUFS1,MRI1,GNE,TKT,AGPAT3,ATP5F1B,SPR,PMVK,MAN1A1,PIP5K1C,EBP,MAT2B,GART,NDUFV1,GATC,NDUFA2,NDUFB4,FUT8,NDUFS8,PTGES3,POLR1B,NDUFA3,IMPA2,LDHB,B3GALT6,AMPD2,TK1,ACP2,GUK1,GALC,LDHA,POLR3GL,ADSL,NADK2,ATP5MF,POLR2A,MTMR3,PLD3,SGSH,ATP6V1D,POLE,ATP5MC3,ACOX1,COX8A,IMPDH1,ACAT1,ACADM,NDUFS5,ATP6V1C1,IDH3B,PGAM1,SAT2,GCSH |
| 4.424e-04 | -7.72 | APBB1 (amyloid beta precursor protein binding family B member 1) | protein interactions | 322 | 96 | 29 | 17029 | 2761 |
WASF2,TSHZ1,CYFIP1,CHERP,SF3B1,PCGF6,TMEM216,DHX9,ATXN1,WIPF1,THRAP3,BLM,CYFIP2,APP,SF3A2,DHX15,PRNP,SF3B2,DDX17,RBM17,CEP104,APLP2,VASP,WAS,PQBP1,KHSRP,YBX1,ABI1,PABPC1 |
| 4.433e-04 | -7.72 | GO_VESICLE_ORGANIZATION | MSigDB lists | GO_VESICLE_ORGANIZATION | 266 | 61 | 17377 | 2626 |
RAB14,CHMP2A,PDCD6IP,GORASP1,SRGN,NKD2,VTI1A,AGFG1,ARF1,SEC16A,FBXO5,ANKRD28,CD59,RAB8A,SNX18,SEC24C,PPP6C,AP1M1,AP2B1,BCL2,CORO1A,CREB1,LMAN1,TFG,F2R,LRSAM1,PPP6R1,SYTL3,TMED2,PREB,SNX8,USO1,TRAPPC9,SNX2,RAB7A,CUL3,MCFD2,CHMP2B,RAB1A,STX16,GOSR1,PICALM,SEC31A,SEC23IP,CHMP4A,GOLGA2,NSF,TMED10,SNAP29,SNAP23,MYO18A,TBPL1,CHMP4B,VPS4A,PPP6R3,CHMP7,AP2S1,ABCA1,CSNK1D,ALS2,SNAPIN |
| 4.452e-04 | -7.72 | GSE17721_LPS_VS_POLYIC_8H_BMDC_UP | MSigDB lists | GSE17721_LPS_VS_POLYIC_8H_BMDC_UP | 182 | 45 | 17377 | 2626 |
SEPHS2,SYS1,POLR2K,RBM8A,PLAGL2,CUL1,SIKE1,SLC4A2,CHAC2,NCKAP1,PSEN1,RAB11A,ABHD14A,PNO1,CSDE1,IRF4,MED8,NOL11,TIMM23,ATP13A3,LTN1,PDIA6,RNF5,ABCC1,ACSL5,AMPD2,TSHZ1,DDX24,AKT2,CAMSAP1,TUBGCP5,RFFL,BOLA1,GFER,MAK16,BTBD1,KPNA1,MAGT1,STT3A,PPP1R11,FAM122A,MRPL13,HRAS,CPEB2,FUBP1 |
| 4.452e-04 | -7.72 | GSE369_SOCS3_KO_VS_IFNG_KO_LIVER_DN | MSigDB lists | GSE369_SOCS3_KO_VS_IFNG_KO_LIVER_DN | 182 | 45 | 17377 | 2626 |
SRM,TOMM20,TXN,MCM10,MRPL42,AGRN,TOR3A,TPX2,PMF1,IFT27,STMN1,ABHD14A,MXD1,HERC3,CAPN2,SIVA1,ATP13A3,RRBP1,PRC1,CEP63,LDLRAD3,SLC12A2,GM2A,TK1,CREG1,TSPAN31,GNG7,MKI67,E2F3,RRM2,FBXO9,NUSAP1,ARHGEF12,ANLN,SHCBP1,HLA-B,RAD18,CEP55,CAMKMT,CDCA5,ATF6,RNASEL,SLC22A23,MZT2B,GCSH |
| 4.452e-04 | -7.72 | GSE1460_NAIVE_CD4_TCELL_ADULT_BLOOD_VS_THYMIC_STROMAL_CELL_UP | MSigDB lists | GSE1460_NAIVE_CD4_TCELL_ADULT_BLOOD_VS_THYMIC_STROMAL_CELL_UP | 182 | 45 | 17377 | 2626 |
USP7,TSC22D3,NACA,AP3M2,CERK,PCSK7,CUL1,LETMD1,BTN3A1,DAZAP2,SNN,MAPK14,CRLF3,IL21R,PCYOX1L,TMEM179B,KRI1,TNFAIP8,SEC24C,PPIL2,LPIN2,SCYL3,NCOA2,ATP6V1G1,RPL35,PBXIP1,TAOK1,FRAT2,SRSF5,DCLRE1C,CBFB,KDM3A,ZNF174,MAT2A,DDX23,ZNF862,TRIM26,STAT6,SAFB,CAB39,DDX5,MRFAP1L1,NDE1,LONP2,DEF6 |
| 4.452e-04 | -7.72 | GSE1460_NAIVE_CD4_TCELL_CORD_BLOOD_VS_THYMIC_STROMAL_CELL_DN | MSigDB lists | GSE1460_NAIVE_CD4_TCELL_CORD_BLOOD_VS_THYMIC_STROMAL_CELL_DN | 182 | 45 | 17377 | 2626 |
PPCS,FEZ2,MRPL42,HJURP,MANBA,CDCA3,MAP1LC3B,PABPC4,PRNP,CD59,OIP5,CCNA2,PTEN,RAB4A,RAD23B,RNASEH2A,IFT46,PDLIM2,IFRD1,RHOBTB3,RHOA,PGGT1B,KIF15,ATXN1,NUP155,RIT1,GALNT7,MCFD2,RAB1A,CHMP2B,VDAC1,ARPC1A,FKBP3,TTC33,RHEB,CHCHD3,DTWD1,DNAJC10,ZNF282,FAM3C,MAP4,SIL1,ATP6V0C,CHPT1,SMNDC1 |
| 4.452e-04 | -7.72 | GSE20715_WT_VS_TLR4_KO_48H_OZONE_LUNG_DN | MSigDB lists | GSE20715_WT_VS_TLR4_KO_48H_OZONE_LUNG_DN | 182 | 45 | 17377 | 2626 |
WSB2,NDUFV2,PPCS,MRPS2,GADD45G,STRN4,NDUFA4,MYO9B,XPR1,GTF2F1,LRRC14,WWP2,RBM17,C12orf10,PSMD2,EXOSC7,SEPT11,TMBIM1,TMED2,FDFT1,TMEM160,UBQLN4,ADAM17,SEC61B,GALC,PRRC2A,PPP1R21,MRPL12,SMU1,ATP6V0A1,ODC1,FADD,SH3BP5,ALG3,MRPL2,KPNA1,HINT1,NAGLU,DBI,LRPPRC,APPL2,COX5A,FAM122A,EYA2,SSRP1 |
| 4.452e-04 | -7.72 | GSE27786_NEUTROPHIL_VS_MONO_MAC_UP | MSigDB lists | GSE27786_NEUTROPHIL_VS_MONO_MAC_UP | 182 | 45 | 17377 | 2626 |
UBL3,C9orf78,DDX47,MAGED1,DCTN2,CDK13,SIRT2,CCNL2,TWF2,MIEN1,PITHD1,FOXO3,PAIP2,ARPC5,RCSD1,ZCCHC2,TAP2,RP2,ABI1,IFT46,TTPAL,CDKN2AIP,RBM42,TACC1,TSPYL4,FOPNL,NSDHL,RIT1,HERPUD2,SH3GLB1,MAPK3,C1orf122,MYO1F,TBC1D17,SERTAD2,GOLGA2,CLK3,DCK,ACADM,TATDN1,AKNA,TMEM159,RAD51D,ZBTB24,TMEM131 |
| 4.452e-04 | -7.72 | GSE5542_IFNG_VS_IFNA_AND_IFNG_TREATED_EPITHELIAL_CELLS_6H_UP | MSigDB lists | GSE5542_IFNG_VS_IFNA_AND_IFNG_TREATED_EPITHELIAL_CELLS_6H_UP | 182 | 45 | 17377 | 2626 |
MIB2,RHOG,ZNF296,PIGN,COPA,DAP,SIRT2,UBE4A,TWF2,MRPL19,EBP,SNRNP25,MDM2,VASP,PDCD10,SUV39H2,CCP110,CWC27,MBD2,BANF1,ACAD8,ST8SIA2,NAA35,S100A6,CGGBP1,ABCC5,ATP6V1G1,USP34,CYFIP1,NXT1,FAM172A,LONRF3,GALC,FOPNL,DDX20,PPWD1,GSTCD,EIF4G2,MARK2,RBM38,TTC13,NSMCE2,TATDN2,BAZ1B,ATXN7L2 |
| 4.452e-04 | -7.72 | GSE13411_PLASMA_CELL_VS_MEMORY_BCELL_DN | MSigDB lists | GSE13411_PLASMA_CELL_VS_MEMORY_BCELL_DN | 182 | 45 | 17377 | 2626 |
WASF2,CDC40,UBXN1,UBE2Z,SMC6,NOTCH2,GGA2,SNN,MAP1LC3B,LYN,PPP1R16B,CUTC,EXT2,GIT2,PIP4K2A,RPL23A,SLC25A36,SP100,INPP5A,ZCCHC2,CORO1A,PIKFYVE,TRIM14,PDLIM2,PTPRK,CSNK1G2,SEPT9,RPS10,CYFIP2,NDRG3,STK17B,RBM38,MYO1F,NECAP2,EIF3K,PFDN5,RPL32,DCK,HPS5,EIF2D,QRSL1,RBMS1,GALNT10,USP11,NUDT3 |
| 4.452e-04 | -7.72 | GSE3982_DC_VS_NEUTROPHIL_DN | MSigDB lists | GSE3982_DC_VS_NEUTROPHIL_DN | 182 | 45 | 17377 | 2626 |
RHOG,REPS2,ADAM10,B4GALT5,FAM53C,BRAP,SNN,RLF,CRLF3,GIT2,CFLAR,ZNF473,PTEN,RALB,ARPC5,RAB35,LPIN2,JOSD1,ATP6V0D1,CTDSP2,IMPA2,PCBP2,EEF1D,ABCC5,PDLIM2,RHOA,BRD4,TNFAIP3,SELPLG,LDB1,FRAT2,PFKFB3,MCL1,SRSF5,DCLRE1C,STK17B,CDK11A,PPP2R5A,JAK1,ETS2,TAB2,NFIL3,CANT1,GALNT10,NUMB |
| 4.452e-04 | -7.72 | GSE9037_CTRL_VS_LPS_1H_STIM_BMDM_UP | MSigDB lists | GSE9037_CTRL_VS_LPS_1H_STIM_BMDM_UP | 182 | 45 | 17377 | 2626 |
WASF2,CCNC,GNPDA1,RAC1,HABP4,TRIO,MYH9,B4GALT1,ABHD14B,GYG1,CCNL2,S1PR2,IFT27,CHD1,FOXO3,PDXP,KLHL20,DNAAF2,XRCC2,LPCAT1,RPL22L1,SOCS5,ZNF524,TRIM8,PPP1R18,LONRF3,HPDL,POLK,NEK7,ZMYM5,ACSL3,C1orf35,PRKRA,RPL27A,RAB22A,RBM38,KPNA4,MID1IP1,CHD3,UBXN2B,KLHL15,USP32,FAM208A,TOB1,SVIP |
| 4.458e-04 | -7.72 | translation factor activity, RNA binding | molecular function | GO:0008135 | 87 | 26 | 17224 | 2647 |
EIF5A,EIF3L,DHX29,EIF3D,GSPT2,AGO2,TUFM,EIF2A,EFL1,EIF1B,EIF4H,EIF4G2,EIF3G,ABCF1,GFM2,EIF3H,EIF3A,MCTS1,EEF2K,EIF3K,EIF2S2,EIF2D,EIF5,GTF2H2,CPEB2,EEF1D |
| 4.459e-04 | -7.72 | HIST1H1C (histone cluster 1 H1 family member c) | protein interactions | 3006 | 105 | 31 | 17029 | 2761 |
PPAN,CYLD,NASP,RBX1,VHL,PRKDC,SUZ12,CUL3,CUL1,WDR5,MCM2,CDC73,POLR2A,PHF6,LMNA,CAND1,DOT1L,DERL1,PAF1,TONSL,MCM5,ZNF746,H2AFX,CTR9,YBX1,ARRB2,CD81,SMURF1,ZC3H3,ZC3HAV1,DDB1 |
| 4.459e-04 | -7.72 | GANAB (glucosidase II alpha subunit) | protein interactions | 23193 | 105 | 31 | 17029 | 2761 |
CCT2,COX15,MRPL9,PRRC2A,PRKCSH,MOGS,BRCA1,MCM2,ATP6V1B2,CUTC,SDHA,ISG15,XRCC5,CSDE1,DERL1,TNS3,TRIM47,RAP1A,HUWE1,UBA5,H2AFX,PRMT7,RUFY3,CLN3,CDK2,ATF2,NIPSNAP2,TERF1,MSH6,TERF2,NIPSNAP1 |
| 4.465e-04 | -7.71 | purine ribonucleoside binding | molecular function | GO:0032550 | 369 | 81 | 17224 | 2647 |
RHOG,RAB14,RAB11B,RAC1,OLA1,TPX2,RRAGC,GLUD1,EFL1,MIEF1,RAB21,RAB8A,RAP1A,CDC42,SAR1A,RALB,RAB35,RAB4A,DNM2,UPRT,SEPT11,SUCLG2,RP2,EIF5,ARL5A,RHOBTB3,NRAS,SEPT9,CGAS,RAB7A,RAB1A,ARL5B,RAB5B,RAB22A,LSG1,RAB2B,ARF4,RHEB,DAP3,SEPT1,RAB24,GUCY1B1,TUBB,RHEBL1,ANXA6,RHOC,GSPT2,RAB23,ARFIP2,RAB6A,ARF1,IFT27,RAB11A,GFM2,RTKN,GTPBP3,ARF5,EFTUD2,DAPK1,GNAI2,RHOA,NOA1,TUFM,GTPBP4,SEPT8,BMS1,KRAS,RIT1,RHOT1,SEPT7,RHOT2,GUF1,RHOB,MFN2,GNAS,ADSS,GNA12,RAB18,PRPS2,EHD4,HRAS |
| 4.476e-04 | -7.71 | TCA cycle | BIOCYC pathways | HUMAN_PWY66-398 | 16 | 9 | 902 | 157 |
SDHB,SUCLG1,IDH3A,MDH2,CS,SUCLG2,MDH1,OGDH,SDHA |
| 4.476e-04 | -7.71 | TCA cycle III (animals) | BIOCYC pathways | META_PWY66-398 | 16 | 9 | 902 | 157 |
SDHB,SUCLG1,IDH3A,MDH2,CS,SUCLG2,MDH1,OGDH,SDHA |
| 4.496e-04 | -7.71 | COPII (Coat Protein 2) Mediated Vesicle Transport | REACTOME pathways | R-HSA-204005 | 69 | 23 | 10287 | 1696 |
USO1,TRAPPC9,GORASP1,MCFD2,RAB1A,SEC16A,ANKRD28,CD59,SEC31A,NAPG,SEC23IP,GOLGA2,NSF,TMED10,SEC24C,PPP6C,PPP6R3,LMAN1,TFG,PPP6R1,CSNK1D,TMED2,PREB |
| 4.496e-04 | -7.71 | Assembly of the pre-replicative complex | REACTOME pathways | R-HSA-68867 | 69 | 23 | 10287 | 1696 |
PSMA8,CDT1,E2F3,PSMB7,PSMA1,CDC6,ORC1,MCM2,PSMB9,PSMD9,PSMB3,PSMC4,PSMD2,PSMA6,PSMD1,RPS27A,PSMD8,PSMD3,MCM5,E2F1,ORC3,E2F2,PSMC1 |
| 4.496e-04 | -7.71 | TP53 Regulates Transcription of DNA Repair Genes | REACTOME pathways | R-HSA-6796648 | 69 | 23 | 10287 | 1696 |
CTDP1,POLR2I,POLR2G,POLR2L,POLR2K,ELOA,PMS2,POLR2D,CDK13,BRCA1,FANCI,POLR2A,SUPT16H,GTF2F1,CCNK,POLR2J,MSH2,TCEA1,ATF2,GTF2H2,CDK12,RAD51D,SSRP1 |
| 4.515e-04 | -7.70 | GO_CYTOSOLIC_PART | MSigDB lists | GO_CYTOSOLIC_PART | 208 | 50 | 17377 | 2626 |
RPS15,RPS2,RPLP2,TSC2,RRM1,RPL15,EIF2AK4,CFLAR,RPL11,MCTS1,RPL23A,PSMD2,PSMD1,RPL17,RPL19,RPL22L1,CCT2,RPL29,UBQLN4,RPL35,RPL8,RPL38,RPL6,RPS10,RRM2,RPS24,RPL27A,CCT8,ERC1,RPS9,RPSA,FADD,RPL36,PI4K2A,PSMC4,RPL37,TSC1,IDE,RPL32,PRDX3,RPS27A,RPS14,HPS5,EIF2D,RPLP1,TICAM1,FAU,RPS26,PSMC1,SNAPIN |
| 4.516e-04 | -7.70 | oligoastrocytoma | COSMIC cancer mutations | oligoastrocytoma | 49 | 17 | 17385 | 2587 |
ATXN3,RB1CC1,CIC,MEMO1,MCCC1,TIA1,KRAS,PPP2CA,CDKN2C,RB1,PTEN,CS,NUP153,H3F3A,CDKN2A,USP34,FUBP1 |
| 4.524e-04 | -7.70 | attachment of spindle microtubules to kinetochore | biological process | GO:0008608 | 21 | 10 | 17256 | 2622 |
ZNF207,RB1,DSN1,ABRAXAS2,CDT1,NUF2,AURKB,KIF2C,MIS12,SEH1L |
| 4.525e-04 | -7.70 | RNF185 (ring finger protein 185) | protein interactions | 91445 | 70 | 23 | 17029 | 2761 |
UBE2D3,UBQLN4,UBE2E2,MAPRE2,CGAS,PHB2,MAGED1,UBE2V1,UBQLN2,PKM,UBE2I,USP21,BCAP31,APP,RHBDD1,DERL1,RPN1,PSMA6,PSMD8,RAD23B,RPN2,RNF5,DVL2 |
| 4.525e-04 | -7.70 | KPNA6 (karyopherin subunit alpha 6) | protein interactions | 23633 | 70 | 23 | 17029 | 2761 |
UNK,NOP2,PHB2,PTTG1,RAC1,CUL3,BRCA1,MCM2,MEAF6,CENPU,LMNA,RPL11,PTPN2,MDM2,KEAP1,STAT1,CDKN1B,ANP32A,NUP153,CHMP4B,KPNA2,FBL,STAT3 |
| 4.525e-04 | -7.70 | EIF3L (eukaryotic translation initiation factor 3 subunit L) | protein interactions | 51386 | 70 | 23 | 17029 | 2761 |
CYLD,EIF3D,CUL1,BRCA1,MCM2,RGS2,EIF1B,KCMF1,EIF3G,GNB2,RPS9,EIF3H,EIF3A,EIF3K,RRN3,SMAD2,C1orf131,AHSA1,ZNF746,DNM2,H2AFX,POLR1B,CD81 |
| 4.526e-04 | -7.70 | GSE37416_0H_VS_24H_F_TULARENSIS_LVS_NEUTROPHIL_UP | MSigDB lists | GSE37416_0H_VS_24H_F_TULARENSIS_LVS_NEUTROPHIL_UP | 177 | 44 | 17377 | 2626 |
TRERF1,ADD1,DYNLL1,WDR13,YTHDC2,KLF13,ARGLU1,PMF1,MAPK14,PSMD9,RMI1,ZNF92,CFLAR,SNX18,TBC1D14,ZNF200,CEP63,CAMK2G,IMPA2,CFL1,ALDH9A1,SRSF11,NASP,FAM172A,CRNKL1,HTATIP2,BCLAF1,MCL1,TOPORS,BICD2,DNAJA1,KLF6,STK17B,HHEX,WAS,MID1IP1,STK38,ACOX1,OAZ2,USP32,FAM122A,CAB39,KPNA2,HIPK3 |
| 4.526e-04 | -7.70 | GSE37416_CTRL_VS_24H_F_TULARENSIS_LVS_NEUTROPHIL_UP | MSigDB lists | GSE37416_CTRL_VS_24H_F_TULARENSIS_LVS_NEUTROPHIL_UP | 177 | 44 | 17377 | 2626 |
DDX58,CMAS,GCLM,PIGM,MAX,TRERF1,ADO,TMX4,SDC2,TMX3,KLF13,TMED3,CRLF3,KIAA1147,EBP,UBXN2A,PCNA,CTSS,ZNRF2,TIMM23,PHF14,GTSE1,FOXN2,ANAPC7,CORO1A,OGG1,IMPA2,ABCC5,SRSF11,NOA1,KCNQ1,PDE3B,ARHGAP15,BOLA3,HHEX,WAS,IDE,PARG,FAM126A,NAA20,FAM208A,PDSS2,ZC3HAV1,DEF6 |
| 4.526e-04 | -7.70 | GSE8868_SPLEEN_VS_INTESTINE_CD11B_POS_CD11C_NEG_DC_UP | MSigDB lists | GSE8868_SPLEEN_VS_INTESTINE_CD11B_POS_CD11C_NEG_DC_UP | 177 | 44 | 17377 | 2626 |
SNX27,PRKAB1,HECA,NSMCE4A,ATXN3,UGP2,FAM53C,DYNLL1,MON1B,CTCF,RGS2,KIAA1147,NFATC3,TBC1D14,JAZF1,ZNF746,ARHGEF1,AP1M1,BRD7,CORO1A,NAA35,LDHB,CDC5L,VPS13B,SP3,NARF,KCTD20,RABIF,BMS1,ICAM2,STX16,POLG2,MARK2,MYO1F,KIF2A,SMAD2,TBPL1,RNF38,LY75,CCDC125,ZC3HAV1,SVIP,RNF114,PDF |
| 4.526e-04 | -7.70 | GSE46242_CTRL_VS_EGR2_DELETED_ANERGIC_TH1_CD4_TCELL_UP | MSigDB lists | GSE46242_CTRL_VS_EGR2_DELETED_ANERGIC_TH1_CD4_TCELL_UP | 177 | 44 | 17377 | 2626 |
CHMP2A,STARD7,KLHL18,NKRF,GGA2,DOCK11,ETS1,REEP5,PIP4K2A,CHKA,DECR1,VASP,SIVA1,ARHGEF1,MECR,ANXA5,TECR,TOP1MT,KCNAB2,TGFB1,ZNF672,ADAM17,AGGF1,POLR2I,SEPT9,TSTA3,SCFD2,LY6E,STK17B,CDK11A,NUCB1,INF2,TMEM127,AGPAT2,STAT6,ERGIC3,DTX4,FKBP5,NCOA1,RRS1,EHD4,CABLES1,PPP2R2D,ZNF511 |
| 4.526e-04 | -7.70 | GSE33424_CD161_HIGH_VS_NEG_CD8_TCELL_DN | MSigDB lists | GSE33424_CD161_HIGH_VS_NEG_CD8_TCELL_DN | 177 | 44 | 17377 | 2626 |
SLC12A7,NDUFB6,CUTA,CDCA3,CDCA8,RACGAP1,SLC29A1,NCKAP1,STMN1,BZW2,HLA-A,FZD6,PCNA,CCNA2,NDUFA2,NVL,SRI,PRC1,MRPL54,KIF22,AFF1,AHCY,METTL9,CPSF4,F2R,MAP4K4,MYBL2,ITM2A,NUSAP1,BRCA1,MCM2,ANLN,GOSR1,MTR,PSMB3,FAS,MRPL55,BIRC5,VPS26B,MRPL27,CCNB2,AP2S1,PFKP,SSRP1 |
| 4.526e-04 | -7.70 | GSE6259_FLT3L_INDUCED_33D1_POS_DC_VS_BCELL_UP | MSigDB lists | GSE6259_FLT3L_INDUCED_33D1_POS_DC_VS_BCELL_UP | 177 | 44 | 17377 | 2626 |
NDUFA5,ST13,POLR2K,RAE1,MRI1,OLA1,STARD7,SDF2L1,ADPGK,WRB,RSAD1,ZNF428,ERH,NOL11,CD3EAP,TIMM23,NSFL1C,GEMIN6,DDX31,TOP1MT,EIF5,MRPL21,GTF2H2,GPD1L,NAGPA,RPAP3,RPL35,WDR18,METTL5,MRPL12,MRPS10,DCUN1D5,DDX39A,SERP1,CLNS1A,TWISTNB,PRDX3,CHCHD1,TPP2,PQBP1,SPCS3,BEND3,NMD3,SSSCA1 |
| 4.526e-04 | -7.70 | GSE37301_COMMON_LYMPHOID_PROGENITOR_VS_CD4_TCELL_UP | MSigDB lists | GSE37301_COMMON_LYMPHOID_PROGENITOR_VS_CD4_TCELL_UP | 177 | 44 | 17377 | 2626 |
SRM,PPP1R2,KLHL21,FAM129A,RBM8A,PLAGL2,KLHL18,AGFG1,SLC25A44,RGS1,DNAJB9,PRNP,IRF4,AKAP8,FBL,AHCYL1,PPA1,TDP1,MAPRE2,KLF10,COQ10B,BTG2,EZR,BCLAF1,RAB1A,PCGF1,GOSR1,TTC33,ARF4,ZFR,TWISTNB,ALG3,UPF1,SYNCRIP,NIP7,TBL3,E2F4,WDR4,NFIL3,PITX1,CEBPG,PDCD11,PGAM1,SMNDC1 |
| 4.534e-04 | -7.70 | positive regulation of cell cycle phase transition | biological process | GO:1901989 | 88 | 26 | 17256 | 2622 |
TGFB1,UBE2E2,BRD4,KMT2E,PHB2,MECP2,CDT1,CUL3,CDC6,CCNB1,PAGR1,RAB11A,CDC73,APP,DDRGK1,PAF1,DTL,RB1,RAD51C,MDM2,NSMCE2,CDCA5,FAM83D,CDC25B,UBE2C,ESPL1 |
| 4.594e-04 | -7.69 | GSE11864_UNTREATED_VS_CSF1_PAM3CYS_IN_MAC_DN | MSigDB lists | GSE11864_UNTREATED_VS_CSF1_PAM3CYS_IN_MAC_DN | 172 | 43 | 17377 | 2626 |
SEPHS2,HIVEP3,IMMT,TMUB1,UGP2,AGRN,PHF23,SEC61G,TMEM41B,PLAGL2,SNRPD3,TMEM165,RMI1,TMEM69,ZNF302,UTP18,MEGF8,NAA50,MDFIC,LMAN1,RYBP,ZNF672,HSDL1,PSMA1,CKAP2L,VDAC1,GAR1,CBFB,LSG1,EML4,USP36,PSMC4,DDX23,SEC61A1,NIP7,PSMD3,GADD45B,DTX4,PPP1R11,SNRPG,MRPL3,PFKP,NXT2 |
| 4.594e-04 | -7.69 | GSE37416_CTRL_VS_12H_F_TULARENSIS_LVS_NEUTROPHIL_DN | MSigDB lists | GSE37416_CTRL_VS_12H_F_TULARENSIS_LVS_NEUTROPHIL_DN | 172 | 43 | 17377 | 2626 |
UGP2,B4GALT5,RBM8A,ALKBH5,MYNN,JMJD6,ORC1,FKBP2,RLF,PHC2,TERF2IP,RAB21,SLC31A1,PSMA6,C4orf3,TNFAIP8,EIF4A3,TBC1D22A,MEA1,PIK3IP1,CYC1,SAP30,ADAM17,NXT1,TNFAIP3,GUK1,ATG9A,NARF,VDAC2,KDM3A,PATL1,RHBDF2,DERL1,SERTAD2,DUSP3,MFAP1,HPS5,PKD2,CHMP4B,PDXK,SRSF3,GPI,CLN3 |
| 4.595e-04 | -7.69 | ribonucleotide biosynthetic process | biological process | GO:0009260 | 161 | 41 | 17256 | 2622 |
GALK1,COX5B,PPCS,UCK2,UCK1,SLC35B2,ATP5F1B,ADPGK,ATP5PF,GART,ATIC,ADCY9,CTPS1,PPCDC,UPRT,ATP6V0A2,SLC26A2,CYC1,ADCY7,AMPD2,TGFB1,GUK1,LDHA,ATP6V0A1,ADSL,OGDH,ATP5MF,PKM,STOML2,ADSS,ATP5MC3,GUCY1B1,PRPS2,IMPDH1,DHTKD1,ACAT1,ATP5F1A,GPI,NIPSNAP2,PGAM1,PFKP |
| 4.596e-04 | -7.69 | myeloid leukocyte activation | biological process | GO:0002274 | 564 | 115 | 17256 | 2622 |
RHOG,ADA2,KARS,RAB14,KMT2E,ADAM10,DYNLL1,RAC1,HEXB,NIT2,NHLRC3,GYG1,MAPK14,LYN,KCMF1,CMTM6,CPNE3,PA2G4,RAP1A,PSMD1,AP1M1,BRI3,TMBIM1,GM2A,KCNAB2,ENPP4,CPNE1,CCT2,TIMP2,NRAS,RAB7A,ARHGAP45,PPIE,CYSTM1,PSMB7,ATP6V0A1,RAB5B,TOLLIP,ALDH3B1,DSN1,AGPAT2,DDOST,SURF4,RAB24,PSMD3,CAB39,CANT1,ADAM9,ATP6V0C,TICAM1,ROCK1,CLU,PDXK,LTA4H,MAPK1,CAPN1,TUBB,SVIP,MIF,DNAJC5,GMFG,MANBA,PDAP1,LAMTOR3,B4GALT1,ASAH1,JMJD6,CDK13,MAN2B1,RAB6A,PSEN1,TMEM179B,GNS,CD59,PSMD2,IRF4,CTSS,ARPC5,HUWE1,OSTF1,CNN2,MVP,LPCAT1,SPTAN1,TGFB1,CYFIP1,FTL,MLEC,RHOA,CREG1,HEBP2,C1orf35,PKM,ARMC8,CCT8,NEU1,HSPA1B,PI4K2A,CAND1,XRCC5,CAT,RAB18,ATP6V1D,MAGT1,GOLGA7,SNAP29,SNAP23,ACLY,PGRMC1,IMPDH1,CTSA,RBPJ,PSAP,GPI,PGAM1 |
| 4.597e-04 | -7.68 | urinary_tract-bladder-carcinoma-transitional_cell_carcinoma | COSMIC cancer mutations | urinary_tract-bladder-carcinoma-transitional_cell_carcinoma | 6194 | 997 | 17385 | 2587 |
CCDC93,HECA,ADD1,TSC2,KDM4A,ABCC10,PIGQ,HEXB,CNTROB,PPP1R16B,PABPC4,EEF2K,CALM2,USF1,GSDMB,RABGAP1L,TTC9C,MECR,PDS5B,DNM2,CRY2,NUP153,RNF26,LRRC59,TIPARP,FTSJ3,PCBP2,USP34,PLK3,ZNF672,ERCC1,ZNF559,NRAS,GABPA,EHMT1,HSDL1,KIF15,HNRNPF,PLEKHM3,SMC2,DIDO1,PPFIA3,WBP1,KRIT1,BRMS1,AHNAK,MID1IP1,RAD18,ZNF689,LIMK1,PRDX5,OGT,COX5A,RNASEL,SMG9,FBXL3,SMAD1,ANXA11,PFKP,SLC25A33,DDX42,HIVEP3,NDUFV2,CLSPN,KIAA0100,GGA1,TRIO,CUTA,HAUS4,SLC4A2,EIF2AK4,APH1B,CDC73,MYL6B,ATG4A,CD59,DDX56,SMC3,RNFT1,FBXO7,FOXN2,NUP85,PABPC1,CARS2,TIMM8B,AGGF1,RB1CC1,ZMYND11,DHX29,MTA2,TEX10,MAN1B1,GTPBP4,MYBL2,UHRF1BP1,MRPL16,CBFA2T2,MPG,ELK1,SFXN5,RHOB,PTPRF,SCARB2,FNTA,KPNA1,CCDC86,SETD3,ZNF830,HEXA,SNX14,RNF139,MRPL3,ALS2,EGLN1,ZNF207,RHOG,ZNF296,TRIM41,ABCA3,TRERF1,IVNS1ABP,UBR2,ACTR3,ANK3,WDTC1,MON1B,C5orf30,MYH9,CREBL2,TBC1D13,NIPA2,NIT2,SLC35B2,PRKACA,STAM,REPS1,APP,PRKD3,ZNF420,AHCTF1,ATP2A2,SP100,TBC1D22A,ZKSCAN1,SH3BP1,UTP18,NUP107,ANKRD13C,ANAPC7,RNF19A,CEP63,FAM76B,MAVS,GPD1L,ZC3H3,GCC1,ARL5A,DCTN1,ADCY7,ENPP4,SNX8,CPNE1,FAM118B,IDH3A,CRNKL1,POLR2D,PFKFB3,ATP6V0A1,HTATIP2,CDCA2,MEF2D,TMEM147,TANC1,GIGYF1,GPR137,DDX17,TAF2,VPS26B,NSMCE2,CORO1C,CAMKMT,WDR7,RNF38,MBOAT1,ZBTB11,USP13,TMBIM4,ZFP91,TRMT6,CCM2,TRAK1,SIKE1,ATG2B,JMJD6,PMVK,KRI1,PPP1R3B,FBXO3,ZBTB45,ITGB8,GATC,HUWE1,PPP1R8,ARHGEF1,LTN1,UBE3B,TTLL12,TPCN1,LYPLA2,SPTAN1,NUDC,STAU1,PPP3CA,DDX24,GALC,ZNF512,MRS2,DDX39A,PDE3B,RPA1,UTP20,SLC19A1,ZNF180,POLE,ACOX1,TATDN2,MAPK6,LRPPRC,LY75,HMGB2,THAP5,FAF1,ANAPC4,AGRN,WDR13,TRIM11,PPP1R15B,FAM129A,YTHDC2,SNX15,RBM8A,MCCC1,CSNK2A1,EBNA1BP2,SND1,S1PR2,GIT2,BIRC2,ATPAF1,KRR1,FANCL,ABL2,DLG5,NUP210,GLIS2,NT5DC1,PIK3R2,ASB6,MRPL32,CCAR1,ABCC5,VPS13B,PTPRK,PLK1,METTL1,CELSR2,MIOS,HARS,MBLAC2,GMFB,LNX2,CDC6,LRP5,PBRM1,BRCA1,ESYT1,ANLN,USP21,LSG1,RHEB,DPYSL3,EPB41,TRAM2,TBC1D17,TIMM13,TONSL,E2F4,ADAM9,QRSL1,ACTB,DVL1,CLN3,FAM208A,NUDT11,NUMB,CTU2,PARP12,ZCCHC9,FAM53C,DNAJB2,CENPF,CTCF,KLC1,ASAH1,RACGAP1,CDK13,RAB6A,NCKAP1,PPP3CB,B4GALT4,DOCK11,RLF,RAPGEF6,LRRC14,TNS3,RB1,C1GALT1,UBE2Q2,VMP1,RINL,ZNF746,PPIL2,TIMELESS,CTR9,AHCY,MDFIC,AHDC1,MAML1,LRSAM1,NIPSNAP1,ABCC1,NTPCR,TRAPPC9,NQO2,ACSL3,LDB1,MEMO1,KRAS,EIF2AK1,RTF1,METTL22,EIF4G2,ARMC8,IRF5,ZNF174,NMT2,PSMC4,GOLGA4,TMEM168,CDC27,NLRC5,FAM122A,PRMT7,SIL1,BTBD10,KCTD7,RPLP2,UGP2,ARID2,FOXM1,XAB2,SLC2A1,TM9SF3,ZADH2,GGPS1,PCBP1,LYN,COMMD8,RAD23A,VAV1,OIP5,CSDE1,PDK2,MDM2,ZNF473,STRBP,BRPF3,WDR44,PDCD2,RPAP1,BCAP29,CABLES2,TOP1MT,AHCYL1,ZNF583,SPSB3,DVL2,SNX25,KDM3B,CLPTM1,MND1,BIRC3,SLC26A6,NUP155,VDAC1,KDM1B,RPSA,USP36,RHBDF2,SUGP1,DNAJC10,IDE,CLK3,RBL1,SCAP,ZNF700,PSMD3,CEP55,ZNF436,XRCC3,LTA4H,USP53,SMAD4,PARD3,ZC3HC1,BCL2L12,SLC30A9,GOLIM4,GNE,ARID5A,ARFIP2,SUMF1,SLC12A9,GGA2,RMI1,BZW2,SCYL2,TUBGCP2,DNAJB9,TFRC,GTPBP3,NDUFV1,SLC1A4,CWC27,ABCD1,ORC3,CAMK2G,RBM15B,YTHDC1,RPAP3,PPAN,RPRD1A,RHOA,ACP2,CSRP1,SNX2,BTAF1,ZNF202,ZMYM5,ABCF2,TOP3A,CCDC34,ARHGEF12,RANGAP1,PCGF1,DDX23,CACNB1,KPNA4,CDKN2AIPNL,SEC23IP,BIRC5,TWSG1,SNAP29,NEIL3,BBX,CDCA7L,FAM126A,NR2F2,HIPK3,SAT2,NUP188,MAX,PNISR,NDUFB6,GXYLT1,PRKCSH,ADAM10,TMEM41B,CXXC1,CUL1,NHLRC3,PLXNA1,EIF1B,SLC20A1,MYEF2,POLR3K,C14orf119,ANKRD26,ZNF428,PA2G4,SNUPN,ASAP2,NOL11,DBNDD1,PARPBP,TRA2B,SUCLG2,TAF5L,SLC26A2,DNMT1,SRP72,ZNF524,SGCE,OSBP2,KLF10,ATG9A,AKT2,NSUN2,MKI67,DDX20,AMDHD2,SLC17A5,AURKB,USP22,FOXRED1,RFC2,SLC25A5,RAB2B,EIF3A,IWS1,DOT1L,ZMYM3,MAP3K4,HHEX,WAS,RBM47,TPP2,WDR4,PTPDC1,ARRB2,RTN3,NMD3,HDAC2,PTOV1,DDX58,WSB2,PPIB,HSPH1,PRPF38B,MAPRE1,EWSR1,MUT,PRKAA1,ANKH,DLGAP4,TATDN3,B4GALT1,KIF23,NDUFA4,NOTCH2,TMEM165,ZNF79,PDXDC1,VPS25,NDUFS7,JMY,WDR48,RTKN,CFLAR,FAM192A,RPN1,EXOSC7,LHX8,KLHL5,LRRC8D,HDAC7,BDH1,MSH2,DAPK1,PIGG,TPST1,CYC1,PIK3IP1,PIKFYVE,ANKHD1,FAM171A1,SYTL3,TMED2,MORC3,SOCS5,PRIM2,ZNF84,RDH10,ZNF574,MFNG,EXOSC9,RIT1,ADRB2,CAPZA2,ARID1A,PLEC,PKM,KDM3A,GOSR1,MAP2K2,CCT8,MTR,PHF6,ADSS,ZNF777,MTHFD2,HSPBP1,GOLGA2,NSF,RBMX,MED15,ACLY,USP32,FAM83D,APPL2,ARAP1,VCPIP1,CABIN1,SMPD4,GPI,MAP3K5,PPP6R2,CDKN2A,ZC3HAV1,DNMT3A,ATXN3,CKLF,REPS2,TRIP10,URB2,SF3B1,RAF1,CAST,SUZ12,RPS6KA1,MAGED1,UROD,KIAA0232,OLA1,AP1B1,SNN,SDHA,GNB2,PHC2,NUDT19,CRKL,TERF2IP,ZNF75D,SHC1,RALB,MTMR4,UCHL5,LPIN2,ADCY9,CDKN1B,BRI3,TTC3,AQR,RBM12B,ILKAP,CDK12,SAP30,ANKLE2,CCT2,CDKN2AIP,MKLN1,HMGN4,ERF,OAF,CUL3,ELP4,SLBP,KIAA1586,EDF1,PKMYT1,GALK2,CDC23,H2AFV,ERC1,DHX57,SUPT16H,ANKZF1,CHMP4A,JAK1,DSN1,HAGHL,PPA2,STAT1,SEL1L,RWDD4,H2AFX,ATF6,KLHDC4,TRIM32,PDCD11,ATMIN,PRPF4B,ANKRD13D,PKP4,NDUFS1,DEPDC1,MECP2,TKT,CBLL1,SLC25A12,ARGLU1,SECISBP2,BLM,SPR,POFUT1,HMG20A,REEP5,FAM8A1,HEATR5B,JAKMIP1,WWP2,MAT2B,RBM17,PTEN,CRAT,CENPJ,FUT8,AXIN2,PTPN11,MRPL54,COPS7B,CNN2,CITED2,MSH6,SMC4,ANKRD37,LONRF3,DENND4C,NET1,DENND1B,ILF3,RFXANK,BMS1,OTUD3,LRRC1,RHOT1,KLF6,GUF1,MACF1,MARK2,MYO1F,NUCB1,FBXO21,SGSH,HGS,PRDX3,TTLL4,ZHX1,TFDP1,DDX5,WDR91,TAF6,ESPL1,PURA,DDB1,FAM83G,DEF6,ESYT2,MIB2,NAT9,SKA3,HNRNPAB,PLXNC1,UBN1,NF1,MOGS,DNAJC24,TAF6L,KIF2C,USP48,BECN1,SNAPC4,RNF103,ZNF696,EDC3,BCAT2,MBD4,ZNF804A,DST,GOT2,SIVA1,ZNHIT6,GPATCH1,AKR1B1,NDUFB9,CNNM3,ARID4A,TRIM14,WDR41,TIMM50,LARS,SNRNP200,LAP3,LRBA,SUMF2,PITPNB,KMT2C,OGFR,SOX4,ASF1B,ABHD5,RPL37,UBTF,CXXC4,MAN2A2,PAF1,EIF4ENIF1,BRWD1,SPATA2,PPM1G,SH3GLB2,MIA2,ATXN2L,BAZ1B,ACBD4,STK11,CLU,CHEK2,TSTD2,SLC12A7,PPP1R2,TM9SF4,NACA,TIA1,MED13L,THRAP3,XPNPEP3,EPHX2,TTF1,SRRT,QSOX2,NUP205,CHKA,DTL,ZNF449,MED10,CAPZA1,ZNF335,KIFAP3,BCL2,UBE3C,ZRANB1,SLC12A2,POLR2I,TSTA3,CIC,SUGP2,GBA,SLTM,ARHGAP15,EVC2,CAND1,MASTL,GNAS,TSC1,NAP1L1,RBM25,NSMF,ODF2,EXOC4,SLC16A1,FN3KRP,PITPNA,NUP62,NAA20,PTDSS1,C7orf26,N4BP2L2,MBD1,TCF12,WASF2,PRKAB1,ASH1L,CORO7,MPHOSPH8,CHERP,WDYHV1,HNRNPUL2,UCK2,PMS2,SMARCA4,PLAGL2,CHKB,CLCC1,MXD1,PAIP1,USP5,SAP130,HNRNPA2B1,FARSA,IARS,NVL,CD3EAP,KIF14,EXOSC1,RPN2,CHTOP,PDIA6,SCYL3,HTRA2,MOSPD1,RLIM,POU2AF1,ACSL5,ZNF500,NLN,ATXN1,OGDH,CADM1,BICD2,HERPUD2,EDEM2,MBD3,GFER,EIF3G,RPS9,BTBD1,RAD54B,PON2,ZNF317,HPS5,STAT6,TULP3,WDR59,ARNTL,CANT1,FKBP5,TMEM101,GAS2,USP11,AKNA,SMURF1,MAPK1,ABCA1,TSPAN5,CBX4,KIF3B,TRIP12,SH2D3A,EYA1,SHPRH,CDK2AP2,SCYL1,LETMD1,PAWR,DCUN1D4,MFSD10,HDDC2,FERMT3,KIF5B,FGFR3,GART,SEC24C,PPIG,RRBP1,TANK,PELO,H2AFY,ARHGEF2,BRD7,ATG13,TTC17,FBL,FRMD8,MYO5A,TELO2,CSNK1G2,DCAF6,ADAM17,TMEM39A,HELB,ASPM,ATP2C1,PPP1R21,RFFL,COG1,WDR81,PRMT2,NDRG3,SYMPK,LEMD2,HLA-B,UPF1,ATAD2,PLAA,ELMO1,OSBPL8,ZNF330,ZC3H7B,ACAT1,MBD6,SRSF3,CENPT,ZMIZ1,IDH3B,ATP6V1C1,HRAS |
| 4.604e-04 | -7.68 | regulated exocytosis | biological process | GO:0045055 | 696 | 138 | 17256 | 2622 |
ADA2,RAB14,ADAM10,HEXB,NHLRC3,GYG1,MAPK14,CMTM6,KCMF1,PCYOX1L,CDK5,PA2G4,PSMD1,RAP1A,AP1M1,KCNAB2,NRAS,ARHGAP45,CYSTM1,RAB5B,AGPAT2,TMED10,CAB39,ATP6V0C,CLU,ROCK1,CAPN1,SVIP,DNAJC5,GMFG,LAMTOR3,ASAH1,B4GALT1,CDK13,MAN2B1,RAB6A,PPP3CB,PSEN1,TMEM179B,CD59,GNS,ARPC5,RIMS3,OSTF1,MVP,LPCAT1,SYTL3,CYFIP1,FTL,CREG1,WDR1,C1orf35,PKM,ARMC8,CCT8,XRCC5,CAND1,PI4K2A,MAGED2,CAT,SNAP23,ACLY,CTSA,GPI,UNC13C,RHOG,RAB11B,DYNLL1,RAC1,OLA1,NIT2,LYN,APP,CPNE3,APLP2,BRPF3,BRI3,CYB5R1,CORO1A,APOOL,TMBIM1,GM2A,CHP1,CPNE1,ENPP4,ARHGAP17,CCT2,TIMP2,RAB7A,PPIE,PSMB7,ATP6V0A1,TOLLIP,ALDH3B1,DSN1,DDOST,SURF4,RAB24,PSMD3,CANT1,PDXK,MAPK1,LTA4H,CHID1,TUBB,MIF,MANBA,PDAP1,HABP4,SRGN,TMX3,PIP5K1C,FERMT3,PSMD2,CTSS,HUWE1,ANXA5,CNN2,TAGLN2,SPTAN1,TGFB1,RHOA,MLEC,FAM49B,HEBP2,NEU1,HSPA1B,RAB18,ATP6V1D,GOLGA7,MAGT1,SNAP29,FAM3C,PGRMC1,IMPDH1,PSAP,PGAM1,SNAPIN |
| 4.609e-04 | -7.68 | proton-exporting ATPase activity | molecular function | GO:0036442 | 28 | 12 | 17224 | 2647 |
ATP6V0B,ATP2A2,ATP2C1,ATP6V0A1,ATP6V0A2,ATP6V0C,ATP5F1B,ATP6V1B2,ATP6V1C1,ATP6V0D1,ATP6V0E1,ATP6V1G1 |
| 4.609e-04 | -7.68 | Bcas2 (breast carcinoma amplified sequence 2) | protein interactions | 68183 | 34 | 14 | 17029 | 2761 |
SNRNP200,XAB2,EFTUD2,CRNKL1,DHX8,DDX5,CTSA,PPWD1,CCNL2,MRPL48,CDK11B,BRIX1,PRPF19,CDC5L |
| 4.609e-04 | -7.68 | ANP32E (acidic nuclear phosphoprotein 32 family member E) | protein interactions | 81611 | 34 | 14 | 17029 | 2761 |
PTPN2,FYTTD1,UNK,RPS2,EWSR1,KPNA1,SMAD2,SNX2,UCHL5,UBA5,ANP32A,AHCYL1,ATP6V1C1,PARD3 |
| 4.609e-04 | -7.68 | KIAA1143 (KIAA1143) | protein interactions | 57456 | 34 | 14 | 17029 | 2761 |
SNRNP200,CDC40,EWSR1,XAB2,PPIE,BUD31,CRNKL1,KIF15,GPATCH1,AQR,ECD,APP,DHX15,CDC5L |
| 4.609e-04 | -7.68 | RECQL (RecQ like helicase) | protein interactions | 5965 | 34 | 14 | 17029 | 2761 |
RECQL,KPNA4,MDM2,MAX,SYNCRIP,E2F4,BANF1,E2F1,MSH2,KPNA2,RBPJ,CREB1,DDB1,RPA1 |
| 4.619e-04 | -7.68 | Cenpe (centromere protein E) | protein interactions | 229841 | 83 | 26 | 17029 | 2761 |
TRIM41,DCTN2,SEC16A,PATL1,MARK2,MATR3,LMNA,DNAJC10,GOLGA4,PCM1,NEK1,CORO1C,SEC24C,STX18,BBX,COX5A,YWHAZ,TOP1MT,SLC12A2,YWHAH,SENP1,DYNC1LI2,IPO4,SEH1L,EEF1D,DCTN1 |
| 4.619e-04 | -7.68 | ETFA (electron transfer flavoprotein subunit alpha) | protein interactions | 2108 | 83 | 26 | 17029 | 2761 |
COX15,IDH3A,UFC1,LDHA,RAB6A,ARF1,RAB1A,VDAC1,DDX39A,PSEN1,PEF1,RAB5B,ARF4,BCAT2,NUP210,EIF2S2,CDC42,ARF5,DDA1,UBA5,SUCLG2,ACADM,ATP5F1A,PPP6R3,LDHB,GPX4 |
| 4.619e-04 | -7.68 | COQ2 (coenzyme Q2, polyprenyltransferase) | protein interactions | 27235 | 83 | 26 | 17029 | 2761 |
TXN,MRPS15,NDUFAF2,MDH2,TKT,VDAC2,RNPS1,BCLAF1,THRAP3,ARF1,SLC25A5,H2AFV,SCYL2,ECH1,PIP5K1C,RCC1L,STOML2,CHCHD3,EPRS,NDUFV1,EIF4A3,SAFB,YWHAZ,CHMP4B,MRPL13,LDHB |
| 4.619e-04 | -7.68 | CDK7 (cyclin dependent kinase 7) | protein interactions | 1022 | 83 | 26 | 17029 | 2761 |
CCT2,CTDP1,PCGF6,HNRNPF,BRCA1,CCNB1,APP,POLR2A,RPA1,RPA2,CCNA2,NEK6,MTA1,E2F1,CDKN1B,FKBP5,TCEA1,RUVBL2,SMAD1,CDK2,ARRB2,CCNB2,GTF2H2,HDAC2,CDC37,SRPK2 |
| 4.619e-04 | -7.68 | PSMB7 (proteasome subunit beta 7) | protein interactions | 5695 | 83 | 26 | 17029 | 2761 |
PLK1,PSMA8,CAST,PSMB7,PSMA1,PSMG1,POMP,SYVN1,PSMB9,PSMB3,PSMC4,RAD23A,KIF5B,DERL1,PSMD2,PSMD1,PSMA6,CLIC4,HUWE1,UCHL5,PSMD8,PSMD3,RAD23B,FBXO7,FUS,PSMC1 |
| 4.619e-04 | -7.68 | PARD6B (par-6 family cell polarity regulator beta) | protein interactions | 84612 | 83 | 26 | 17029 | 2761 |
CLPTM1,GOLIM4,AGGF1,FOXM1,UBR2,RAC1,DLGAP4,CDCA3,GMCL1,APP,KIFC1,GNS,CCNK,MKNK1,GOLGA2,CDC42,MRPL55,KBTBD7,IARS2,LTN1,YWHAZ,TP53BP2,SLF1,YWHAH,PARD3,PDF |
| 4.634e-04 | -7.68 | COPI-coated vesicle membrane | cellular component | GO:0030663 | 18 | 9 | 18223 | 2701 |
TMED7,COPA,COPE,SCYL1,TMED3,COPG2,COPB2,TMED2,KDELR1 |
| 4.676e-04 | -7.67 | Myb_DNA-binding | pfam domains | PF00249 | 25 | 11 | 17054 | 2545 |
DNAJC2,NCOR2,MTA1,MIER1,MYBL2,RCOR1,RCOR3,MYBL1,TERF1,SNAPC4,TERF2 |
| 4.689e-04 | -7.67 | Chronic myeloid leukemia | KEGG pathways | ko05220 | 71 | 23 | 7161 | 1149 |
TGFB1,NRAS,RAF1,AKT2,E2F3,KRAS,BCL2L1,MAP2K2,MAPK3,CRKL,RB1,MDM2,SHC1,PIK3R2,E2F1,PTPN11,CDKN1B,MAPK1,E2F2,HRAS,SMAD4,CDKN2A,HDAC2 |
| 4.689e-04 | -7.67 | Chronic myeloid leukemia | KEGG pathways | hsa05220 | 71 | 23 | 7161 | 1149 |
TGFB1,NRAS,RAF1,AKT2,E2F3,KRAS,BCL2L1,MAP2K2,MAPK3,CRKL,RB1,MDM2,SHC1,PIK3R2,E2F1,PTPN11,CDKN1B,MAPK1,E2F2,HRAS,SMAD4,CDKN2A,HDAC2 |
| 4.722e-04 | -7.66 | EIF5A2 (eukaryotic translation initiation factor 5A2) | protein interactions | 56648 | 20 | 10 | 17029 | 2761 |
PPIB,EWSR1,DHPS,VHL,CUL3,EZR,TAGLN2,CDC23,CDK2,OPTN |
| 4.722e-04 | -7.66 | FAM45A (family with sequence similarity 45 member A) | protein interactions | 404636 | 20 | 10 | 17029 | 2761 |
CCDC93,COMMD10,VPS26C,KBTBD7,COMMD5,COMMD4,COMMD6,COMMD8,VPS29,NMT2 |
| 4.722e-04 | -7.66 | LACTB2 (lactamase beta 2) | protein interactions | 51110 | 20 | 10 | 17029 | 2761 |
TXNL1,PDCD6IP,NUP210,SIAH1,WDR1,GPI,NDRG3,HAGH,COIL,LYPLA2 |
| 4.722e-04 | -7.66 | RNF113A (ring finger protein 113A) | protein interactions | 7737 | 20 | 10 | 17029 | 2761 |
SNRNP200,TRIM8,EWSR1,RBM8A,ILF3,CSNK2A1,CCAR1,LMNA,TERF2,SF3B2 |
| 4.722e-04 | -7.66 | RPUSD4 (RNA pseudouridylate synthase domain containing 4) | protein interactions | 84881 | 20 | 10 | 17029 | 2761 |
DDX28,SYNCRIP,RBM42,MRPL39,MRPL12,CYC1,IKBIP,MRM3,SSSCA1,RCC1L |
| 4.734e-04 | -7.66 | GABRIELY_MIR21_TARGETS | MSigDB lists | GABRIELY_MIR21_TARGETS | 272 | 62 | 17377 | 2626 |
RMND5A,USP7,SUZ12,GNE,YTHDC2,RRAGC,PM20D2,ZADH2,MYEF2,FANCI,ANKRD28,FBXO3,PPP1R3B,SLC31A1,ITGB8,ZNF326,MSH2,RP2,SLC26A2,ZRANB1,ATF2,STAT3,MTPN,ARID4A,SRPK2,USP34,SRSF11,PHF20L1,RHOBTB3,TACC1,NEK7,CUL3,SREK1,RTF1,ARHGEF12,PBRM1,SLC17A5,HERPUD2,TTC33,RAB22A,GOLGA4,NEK1,CCDC14,CERS6,KLHL15,ZNF367,FAM3C,KBTBD7,LMBR1,RNF38,PTAR1,MEGF9,PKD2,PTPDC1,MYO9A,RUFY3,GLCCI1,PURA,DYNC1LI2,PDCD4,ALS2,ESYT2 |
| 4.740e-04 | -7.65 | DCAF7 (DDB1 and CUL4 associated factor 7) | protein interactions | 10238 | 119 | 34 | 17029 | 2761 |
GPBP1L1,FAM53C,DYNLL1,AGO2,CSNK2A1,PRKACA,BIRC2,APP,FBRS,DDA1,GTSE1,RNF169,RYBP,PLK1,CCT2,FOXK1,BIRC3,ERF,NET1,NFATC2,RAB3IP,BRCA1,CCT8,BBS12,SMAD2,HIPK2,YWHAZ,PTPDC1,COPS6,YWHAH,GLCCI1,DDB1,PARD3,NUMB |
| 4.758e-04 | -7.65 | endosome membrane | cellular component | GO:0010008 | 451 | 93 | 18223 | 2701 |
RAB14,SNX27,CHMP2A,GNPNAT1,RAB11B,RAC1,VTI1A,ZFYVE21,BECN1,RUFY1,STAM,CD320,ATP6V0B,RAB21,RAB8A,MTMR4,WDR44,RAB35,RAB4A,CLCN6,ZFYVE27,AP2B1,MARCH2,TMEM9,TMBIM1,SNX8,SNX25,CLCN3,ATG9A,RAB7A,ATP6V0A1,CHMP2B,RAB5B,RAB22A,PLEKHF2,OPTN,CHMP4A,TAB2,GRIPAP1,RPS27A,TICAM1,ATP6V0C,CHMP4B,VPS4A,AP2S1,ATP6V0E1,STARD3NL,UBE2D3,GOLIM4,ANXA6,GGA1,HLA-E,CDIP1,RAB23,LAMTOR3,ACAP1,VPS45,GGA2,TMEM165,RAB11A,SCYL2,VPS25,TFRC,HLA-A,PIP5K1C,SPPL2A,SNX18,ZNRF2,ATP6V0A2,PIKFYVE,ATP6V0D1,TPCN1,SNX2,RFFL,WDR81,ADRB2,APPL1,SPPL2B,RMC1,RHOB,PI4K2A,HLA-B,SCARB2,HGS,OSBPL11,LAMTOR4,PML,APPL2,WDR91,EHD4,CHMP7,SNX14,VPS29 |
| 4.768e-04 | -7.65 | EIF4A2 (eukaryotic translation initiation factor 4A2) | protein interactions | 1974 | 66 | 22 | 17029 | 2761 |
UNK,EIF3L,TK1,CYLD,EIF3D,LAGE3,BRCA1,MCM2,EIF4G2,RPSA,EIF3H,EIF3A,CLNS1A,EIF3K,GOLGA2,EIF4A3,CRY2,MCPH1,CD81,PABPC1,PDCD4,CDC5L |
| 4.768e-04 | -7.65 | DDX54 (DEAD-box helicase 54) | protein interactions | 79039 | 66 | 22 | 17029 | 2761 |
NOL12,SRP72,PPAN,NIFK,POLR2G,RRP15,ZNF512,MECP2,CSNK2A1,BRCA1,CNTROB,RBM4,APP,SYNCRIP,DGCR8,CENPJ,RBM34,RPS14,ZNF746,NOC2L,SMURF1,IFI16 |
| 4.769e-04 | -7.65 | Human Thyroid Stimulating Hormone (TSH) signaling pathway | WikiPathways | WP2032 | 68 | 22 | 5312 | 837 |
PDPK1,RAF1,RPS6KA1,MAPK14,TTF1,MAPK3,GNAS,GNA12,RB1,RAP1A,JAK1,PIK3R2,E2F1,STAT1,CDKN1B,CREB1,STAT3,MAPK1,CDK2,GNAI2,HRAS,MYL12B |
| 4.774e-04 | -7.65 | meningothelial | COSMIC cancer mutations | meningothelial | 18 | 9 | 17385 | 2587 |
CDKN2C,RB1,KRAS,NRAS,NF1,PTEN,HRAS,SMAD4,CDKN2A |
| 4.774e-04 | -7.65 | meninges-meningioma-meningothelial | COSMIC cancer mutations | meninges-meningioma-meningothelial | 18 | 9 | 17385 | 2587 |
CDKN2C,RB1,KRAS,NRAS,NF1,PTEN,HRAS,SMAD4,CDKN2A |
| 4.774e-04 | -7.65 | fibroblastic | COSMIC cancer mutations | fibroblastic | 18 | 9 | 17385 | 2587 |
CDKN2C,RB1,KRAS,NRAS,NF1,PTEN,HRAS,SMAD4,CDKN2A |
| 4.801e-04 | -7.64 | GO_REGULATION_OF_KINASE_ACTIVITY | MSigDB lists | GO_REGULATION_OF_KINASE_ACTIVITY | 747 | 146 | 17377 | 2626 |
CCNC,FGFR1OP,TXN,TSC2,NF1,CCNL2,S1PR2,MAPK14,PARK7,CALM2,CDK5,CDKN2C,RAP1A,CDC42,PIK3R2,CDC25B,CDC37,PLK1,BAK1,COPS8,NCK1,GMFB,LRP5,CDC6,PRPSAP1,MAP3K4,HHEX,RPS27A,AXIN1,SOCS4,CAB39,ADAM9,STK11,CLU,DVL1,PDCD4,HSPH1,GMFG,CLSPN,PRKAA1,VAV2,GADD45G,CIB1,RGS2,PSEN1,TFAP4,RB1,FBXO7,MDFIC,PIK3IP1,MVP,GNAI2,SOCS5,MAPKAPK3,LDB1,GBA,GTPBP4,KRAS,MAP4K3,ADRB2,MAP2K2,MBIP,TSC1,DUSP3,CSK,NLRC5,NUP62,MAP3K5,ALS2,CDKN2A,BCCIP,PRKAB1,TRAF7,RAF1,MAGED1,RAC1,TPX2,LYN,PRKACA,DUSP22,APP,CRKL,CCNA2,SHC1,RALB,KIF14,ADCY9,SOCS6,CDKN1B,F2R,CDK12,ABI1,DVL2,ADCY7,PSRC1,CUL3,ELP4,PKMYT1,DNAJA1,SOCS7,PPP2CA,PPP2R5A,TAB2,RBL1,CORO1C,STK38,GADD45B,RPLP1,MAPK1,LRP8,MIF,ZFP91,AKT1S1,BLM,CCNK,PTPN2,FGFR3,PDCD10,PTEN,PTPN11,H2AFY,MAP3K14,TGFB1,PDPK1,TELO2,ADAM17,RHOA,TNFAIP3,PRKAR1B,JTB,MEN1,ZP3,MARK2,MAPK3,SH3BP5,HGS,PRDX3,GPS2,OSBPL8,PKD2,NR2F2,UBE2C,CD81,HRAS,HIPK3,FAF1 |
| 4.814e-04 | -7.64 | TBC/RABGAPs | REACTOME pathways | R-HSA-8854214 | 45 | 17 | 10287 | 1696 |
TSC1,RAB8A,TBC1D17,TSC2,RAB11B,GGA1,RAB35,RAB7A,TBC1D14,RAB4A,TBC1D13,RAB6A,GGA2,MAP1LC3B,RAB5B,RAB11A,OPTN |
| 4.814e-04 | -7.64 | Transport of Mature mRNAs Derived from Intronless Transcripts | REACTOME pathways | R-HSA-159234 | 45 | 17 | 10287 | 1696 |
NDC1,NUP188,RAE1,NUP54,SLBP,NUP155,SYMPK,NUP205,NUP210,NUP107,NUP153,NUP62,CPSF4,NUP58,NUP85,SEH1L,AAAS |
| 4.817e-04 | -7.64 | plasma membrane respiratory chain | cellular component | GO:0070470 | 4 | 4 | 18223 | 2701 |
NDUFV2,NDUFS1,SDHA,NDUFS7 |
| 4.818e-04 | -7.64 | RFC4 (replication factor C subunit 4) | protein interactions | 5984 | 92 | 28 | 17029 | 2761 |
RFC3,BRD4,EWSR1,CHTF18,DHX9,NFATC2,BRCA1,MPG,RFC2,ABCF1,FKBP3,RPA1,TAF2,RPA2,EPRS,PCNA,SETD3,QARS,ZNF746,PML,RTCB,USP20,TARDBP,TAF12,RUVBL2,TAF6,HNRNPM,CDC5L |
| 4.818e-04 | -7.64 | ZWINT (ZW10 interacting kinetochore protein) | protein interactions | 11130 | 92 | 28 | 17029 | 2761 |
TCF12,LYRM4,HNRNPF,MTMR6,NUF2,PMF1,AP3S1,BECN1,APP,TRIM28,MIS12,DDX17,SUGP1,DSN1,RBM25,FBXO28,DGCR8,ARPC5,CCDC14,SNAP29,STX18,RRBP1,PPA2,SLC25A19,DDX5,CLU,TAF12,IPO4 |
| 4.829e-04 | -7.64 | oligodendroglioma_Grade_II | COSMIC cancer mutations | oligodendroglioma_Grade_II | 76 | 23 | 17385 | 2587 |
PDCD6IP,NRAS,NF1,VHL,CIC,COPE,KRAS,SLC4A2,PLXNA1,SEC16A,MACF1,GNAS,CDKN2C,FGFR3,RB1,AHNAK,GOLGA4,PTEN,AKNA,H3F3A,HRAS,CDKN2A,FUBP1 |
| 4.834e-04 | -7.63 | PSMD3 (proteasome 26S subunit, non-ATPase 3) | protein interactions | 5709 | 133 | 37 | 17029 | 2761 |
CYLD,PTP4A3,BLM,SPR,PSMD9,KCMF1,UBLCP1,RAD23A,PSMD2,PSMD1,PSMA6,HUWE1,UCHL5,AHSA1,ZNF746,CRY2,ATP6V0D1,CDC5L,TXNL1,STAU1,PSMA8,PSMB7,PSMA1,BRCA1,MCM2,MCFD2,PSMB9,SF3A2,PSMB3,STOML2,PSMC4,PPP2CA,DERL1,PSMD8,ECPAS,CDK2,PSMC1 |
| 4.834e-04 | -7.63 | U2-type catalytic step 2 spliceosome | cellular component | GO:0071007 | 29 | 12 | 18223 | 2701 |
CDC40,SNRPB,XAB2,EFTUD2,PPIE,CRNKL1,BUD31,DHX8,AQR,SNRPD3,CDC5L,PRPF19 |
| 4.836e-04 | -7.63 | regulation of posttranscriptional gene silencing | biological process | GO:0060147 | 112 | 31 | 17256 | 2622 |
TGFB1,NCOR2,PPP3CA,NDC1,POLR2I,NUP188,POLR2G,POLR2L,POLR2K,RAE1,AGO2,DHX9,NUP54,POLR2D,NUP155,FXR1,MAP2K2,NUP205,POLR2A,NUP210,POLR2J,NUP107,NUP62,NUP153,DDX5,H3F3A,STAT3,NUP85,NUP58,AAAS,SEH1L |
| 4.836e-04 | -7.63 | regulation of gene silencing by RNA | biological process | GO:0060966 | 112 | 31 | 17256 | 2622 |
TGFB1,NCOR2,PPP3CA,NDC1,POLR2I,NUP188,POLR2G,POLR2L,POLR2K,RAE1,AGO2,DHX9,NUP54,POLR2D,NUP155,FXR1,MAP2K2,NUP205,POLR2A,NUP210,POLR2J,NUP107,NUP62,NUP153,DDX5,H3F3A,STAT3,NUP85,NUP58,AAAS,SEH1L |
| 4.853e-04 | -7.63 | RNF11 (ring finger protein 11) | protein interactions | 26994 | 110 | 32 | 17029 | 2761 |
UBE2D3,USP7,UBE2E2,PDCD6IP,GGA1,EPN1,CSNK2A1,UBQLN2,GGA2,APP,USP5,WWP2,PSMD2,PSMD1,HUWE1,TNPO2,AP2B1,CSNK1G3,UBQLN4,TNFAIP3,CCDC127,OPTN,HGS,RPS27A,QARS,PSMD3,PSMD8,STAT1,SNRNP70,SMURF1,SMAD4,AP2S1 |
| 4.886e-04 | -7.62 | NADH dehydrogenase (ubiquinone) Fe-S protein/flavoprotein complex, mitochondria | KEGG pathways | hsa_M00143 | 11 | 7 | 7161 | 1149 |
NDUFV2,NDUFS8,NDUFV1,NDUFS5,NDUFS1,NDUFS7,NDUFS4 |
| 4.886e-04 | -7.62 | NADH dehydrogenase (ubiquinone) Fe-S protein/flavoprotein complex, mitochondria | KEGG pathways | M00143 | 11 | 7 | 7161 | 1149 |
NDUFV2,NDUFS8,NDUFV1,NDUFS5,NDUFS1,NDUFS7,NDUFS4 |
| 4.887e-04 | -7.62 | AMOT (angiomotin) | protein interactions | 154796 | 101 | 30 | 17029 | 2761 |
ARHGAP17,EWSR1,FOXK1,WDYHV1,DYNLL1,USP42,CUL3,AURKB,CNTROB,HAUS2,APP,XPR1,MAPK3,WWP2,ANKRD26,VASP,SEPT1,PTEN,RAB35,PIN1,ACTB,FUS,TP53BP2,USP11,MOB1A,NIPSNAP2,LONP2,RAB3IL1,PARD3,NIPSNAP1 |
| 4.887e-04 | -7.62 | PTPN2 (protein tyrosine phosphatase, non-receptor type 2) | protein interactions | 5771 | 101 | 30 | 17029 | 2761 |
GOLIM4,HMGN5,HARS,TMEM216,BRIX1,GAR1,APP,PNO1,PSMC4,CDK5,DNAJC10,PSMD2,APLP2,PSMD1,KPNA1,SHC1,JAK1,UCHL5,PSMD8,STAT6,GRSF1,RBM34,STAT1,ANP32E,CDK2,STAT3,PSMC1,MRM3,FTSJ3,BYSL |
| 4.894e-04 | -7.62 | haematopoietic_and_lymphoid_tissue-kidney-lymphoid_neoplasm-Burkitt_lymphoma | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-kidney-lymphoid_neoplasm-Burkitt_lymphoma | 4 | 4 | 17385 | 2587 |
RB1,KRAS,NRAS,HRAS |
| 4.894e-04 | -7.62 | haematopoietic_and_lymphoid_tissue-central_nervous_system-lymphoid_neoplasm-Burkitt_lymphoma | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-central_nervous_system-lymphoid_neoplasm-Burkitt_lymphoma | 4 | 4 | 17385 | 2587 |
RB1,KRAS,NRAS,HRAS |
| 4.894e-04 | -7.62 | inverted | COSMIC cancer mutations | inverted | 4 | 4 | 17385 | 2587 |
FGFR3,KRAS,NRAS,HRAS |
| 4.894e-04 | -7.62 | haematopoietic_and_lymphoid_tissue-pleura-lymphoid_neoplasm-diffuse_large_B_cell_lymphoma | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-pleura-lymphoid_neoplasm-diffuse_large_B_cell_lymphoma | 4 | 4 | 17385 | 2587 |
RB1,KRAS,NRAS,HRAS |
| 4.894e-04 | -7.62 | vocal_cord | COSMIC cancer mutations | vocal_cord | 4 | 4 | 17385 | 2587 |
KRAS,NRAS,HRAS,CDKN2A |
| 4.894e-04 | -7.62 | haematopoietic_and_lymphoid_tissue-skin-lymphoid_neoplasm-Burkitt_lymphoma | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-skin-lymphoid_neoplasm-Burkitt_lymphoma | 4 | 4 | 17385 | 2587 |
RB1,KRAS,NRAS,HRAS |
| 4.894e-04 | -7.62 | upper_aerodigestive_tract-vocal_cord-carcinoma-squamous_cell_carcinoma | COSMIC cancer mutations | upper_aerodigestive_tract-vocal_cord-carcinoma-squamous_cell_carcinoma | 4 | 4 | 17385 | 2587 |
KRAS,NRAS,HRAS,CDKN2A |
| 4.894e-04 | -7.62 | urinary_tract-bladder-papilloma-inverted | COSMIC cancer mutations | urinary_tract-bladder-papilloma-inverted | 4 | 4 | 17385 | 2587 |
FGFR3,KRAS,NRAS,HRAS |
| 4.896e-04 | -7.62 | GO_THIOL_DEPENDENT_UBIQUITIN_SPECIFIC_PROTEASE_ACTIVITY | MSigDB lists | GO_THIOL_DEPENDENT_UBIQUITIN_SPECIFIC_PROTEASE_ACTIVITY | 75 | 23 | 17377 | 2626 |
OTUD5,USP7,CYLD,ATXN3,TNFAIP3,USP42,USP10,USP22,OTUD3,USP48,USP21,USP36,USP5,ANKZF1,UCHL5,USP32,VCPIP1,USP20,JOSD1,ZRANB1,USP11,USP34,USP13 |
| 4.896e-04 | -7.62 | MORI_SMALL_PRE_BII_LYMPHOCYTE_DN | MSigDB lists | MORI_SMALL_PRE_BII_LYMPHOCYTE_DN | 75 | 23 | 17377 | 2626 |
IER2,HSPH1,RPS2,NASP,MOGS,WDHD1,PACS1,DNAJB1,VKORC1,SLC20A1,PIP4K2A,RPSA,RPA1,NFATC3,CDCA4,ATP1A1,SEC61A1,RBL1,JOSD1,BCL2,RPN2,DTD1,SMC4 |
| 4.906e-04 | -7.62 | chr1q22 | MSigDB lists | chr1q22 | 66 | 21 | 17377 | 2626 |
PIGM,ASH1L,PBXIP1,DCAF8,GBA,UBE2Q1,PMF1,SLC25A44,KRTCAP2,SLC50A1,USP21,YY1AP1,FLAD1,USF1,DAP3,ANP32E,ATF6,IFI16,GPATCH4,ALDH9A1,SNAPIN |
| 4.906e-04 | -7.62 | HUANG_GATA2_TARGETS_DN | MSigDB lists | HUANG_GATA2_TARGETS_DN | 66 | 21 | 17377 | 2626 |
PIGT,TACC1,EIF3D,SLC2A1,TMEM109,PLAGL2,RCOR1,DCTD,JMJD6,TFRC,MTHFD2,SLC1A4,NSF,FAM3C,NUP107,ACTB,TCOF1,CLU,E2F2,PDCD4,SSSCA1 |
| 4.906e-04 | -7.62 | LIU_COMMON_CANCER_GENES | MSigDB lists | LIU_COMMON_CANCER_GENES | 66 | 21 | 17377 | 2626 |
UBQLN4,LARS,DCAF6,TMBIM4,DLGAP4,ATP6V0A1,NLN,CDK13,ERC1,HAUS2,SERP1,YY1AP1,RDH11,UBXN2A,SYNCRIP,NSMCE2,ZC3H7B,GTSE1,NDUFS8,POLR1B,USP34 |
| 4.921e-04 | -7.62 | GO_REGULATION_OF_CYTOPLASMIC_TRANSPORT | MSigDB lists | GO_REGULATION_OF_CYTOPLASMIC_TRANSPORT | 460 | 96 | 17377 | 2626 |
ZBED3,CYLD,TXN,CHERP,NF1,ZDHHC8,STARD7,PLAGL2,PRKACA,MAPK14,LYN,RBM4,PARK7,BCAP31,CDK5,CALM2,RAB21,RAP1A,MDM2,SP100,ATP2A2,PIK3R2,SRI,PARL,NUP153,CORO1A,MAVS,CYB5R1,F2R,OGG1,ZC3H3,HTRA2,BAK1,GOPC,PSMB7,EZR,BRCA1,NUTF2,SOX4,EDEM2,TRIM28,USP36,IWS1,TONSL,PSMD8,AXIN1,ZNF268,MAPK1,SMAD4,AAAS,SVIP,DDX58,UBE2D3,PPP1R12A,RAB23,NUP54,PPP3CB,ARF1,FKBP1A,HUWE1,RIMS3,AXIN2,FAM89B,PTPN11,GTSE1,ATG13,MDFIC,BCL2,MYO5A,PDPK1,TGFB1,PPP3CA,GCC2,RHOA,KAT2A,NUDT4,ACSL3,RANGAP1,MAP2K2,SH3GLB1,PRDX1,MAPK3,AKAP1,KEAP1,KPNA1,CSK,STX18,PML,PPP3R1,NUP62,PKD2,PARP10,RNF139,FAF1,CDKN2A,SNAPIN |
| 4.927e-04 | -7.62 | negative regulation of nucleobase-containing compound metabolic process | biological process | GO:0045934 | 1451 | 265 | 17256 | 2622 |
TXN,ZNF496,MAX,H2AFZ,KDM4A,TSC22D3,UBE2I,CDK5,PA2G4,CIPC,PARPBP,SRSF4,TRA2B,CRY2,FNIP2,SMARCE1,DNMT1,SRSF10,PLK3,ERCC1,KLF10,GABPA,EHMT1,DDX20,AURKB,DOT1L,BRMS1,HHEX,SMAD2,RPS27A,RPS14,AXIN1,PRDX5,TFDP2,HDAC2,PDCD4,DHX9,PARN,PSEN1,CDC73,TFAP4,SMC3,KLF16,HDAC7,PHF14,MSH2,GNAI2,TNRC18,PABPC1,TERF2,RBM42,ETV3,FOXK1,ZMYND11,MTA2,GTPBP4,BCLAF1,ARID1A,CBFA2T2,PHF6,XRCC5,PFDN5,ETS2,RBMX,QARS,YY1,ZNF830,CDK2,CDKN2A,EGLN1,ZNF296,DNMT3A,SUZ12,UBR2,MAGED1,WDTC1,RCOR3,TERF2IP,SPINDOC,SHC1,SP100,MTA1,CDKN1B,RBM15,ATF2,CGGBP1,RNF169,SAP30,ERF,EID1,DRAP1,CIRBP,CUL3,RNPS1,H2AFV,TRIM28,CHCHD3,ZNF282,HIPK2,H2AFX,STAT1,BEND3,LRP8,POLQ,NCOR2,DEPDC1,SRSF6,MECP2,TCF3,SECISBP2,BLM,HMG20A,FOXO3,MAD2L2,WWP2,SUV39H2,AXIN2,CITED2,CREB1,MSH6,NCOA2,TSHZ1,PPP3CA,ILF3,ZP3,CBX3,GPS2,ZHX1,PITX1,LRPPRC,PML,HMGB2,DDX5,IGBP1,PURA,RORB,THOC1,TRIM11,SIRT2,MAPK14,CREM,CYREN,GLIS2,JAZF1,ZNF639,ETV6,NOC2L,OGG1,ARID4A,CCAR1,PTPRK,RYBP,SP3,PLK1,DEAF1,BAZ2A,NCK1,PBXIP1,VHL,RIOX2,EZR,CDC6,BRCA1,PAF1,TONSL,ZNF268,CHEK2,BEND6,RPS26,POT1,ZNF564,UBE2D3,PHB2,CENPF,CTCF,MEF2A,DNAJB1,THRAP3,TTF1,LYAR,RB1,NFATC3,MLX,TIGAR,MBD2,ZNF746,TIMELESS,CTR9,YBX1,MDFIC,MCPH1,ZNF189,CREG1,CIC,LDB1,RTF1,ZNF174,SYNCRIP,KLHL15,NFIL3,SIAH2,ZFP90,RUVBL2,TOB1,N4BP2L2,MBD1,MPHOSPH8,FOXM1,SMARCA4,IRF3,DUSP22,MXD1,PAIP1,SAP130,HNRNPA2B1,ZBTB21,MDM2,TARDBP,STRAP,MOSPD1,RLIM,PPIF,FAM172A,ZNF500,BTG2,PCGF6,ATXN1,NFATC2,MBD3,RBL1,STAT6,MAFK,ARNTL,DNAJC17,H3F3A,SMAD4,CBX4,DNAJC2,TRIP12,DAP,ARID5A,NKRF,PAWR,MXD4,PTPN2,KMT5A,BRD7,H2AFY,STAT3,RBM15B,TGFB1,RHOA,HELB,ZNF202,PSPC1,BTAF1,RCOR1,MEN1,PRMT2,BIRC5,E2F1,RBPJ,NR2F2,TERF1,IFI16 |
| 4.950e-04 | -7.61 | FAM72 | pfam domains | PF14976 | 4 | 4 | 17054 | 2545 |
FAM72B,FAM72C,FAM72D,FAM72A |
| 4.955e-04 | -7.61 | GSE20500_CTRL_VS_RARA_ANTAGONIST_TREATED_CD4_TCELL_UP | MSigDB lists | GSE20500_CTRL_VS_RARA_ANTAGONIST_TREATED_CD4_TCELL_UP | 188 | 46 | 17377 | 2626 |
NCOR2,ANKRD27,TMEM184B,SRSF6,CENPF,KCTD17,KLC1,IRF3,FOXO3,METTL3,GNB2,NUP205,SAC3D1,AHCTF1,MTA1,MEA1,CLCN6,PRC1,NOC2L,AFF1,CNN2,NUP85,MICAL3,PDLIM2,KDM3B,PTPN18,SNRNP200,SELPLG,SLC25A22,CYFIP2,RHOT1,FADD,MYO1F,NECAP2,C19orf54,ZNF180,TBC1D17,CDCA4,KIF18B,CSK,CORO1C,USP20,NUP62,NDE1,B4GALT3,CBX4 |
| 4.955e-04 | -7.61 | GSE22103_LPS_VS_GMCSF_AND_IFNG_STIM_NEUTROPHIL_DN | MSigDB lists | GSE22103_LPS_VS_GMCSF_AND_IFNG_STIM_NEUTROPHIL_DN | 188 | 46 | 17377 | 2626 |
WSB2,MBD1,SNX27,IMMT,GGNBP2,ARID2,URB2,ZFP91,TRAK1,CDK13,AGFG1,PDCD7,IL21R,RNF103,FKBP1A,CAPN2,PSMD2,ZBTB45,MED8,CCP110,ATP13A3,PPP4R1,PPP6C,F2R,SCYL3,CTDSP2,PACS2,SOCS5,ERCC1,NXT1,TMEM115,BIRC3,ELL2,EDEM2,ZNF407,BSDC1,NEU1,TMEM127,KPNA4,GOLGA4,TTLL4,CCDC6,DGCR8,NAA20,SLC25A33,ATMIN |
| 4.955e-04 | -7.61 | GSE39556_CD8A_DC_VS_NK_CELL_MOUSE_3H_POST_POLYIC_INJ_DN | MSigDB lists | GSE39556_CD8A_DC_VS_NK_CELL_MOUSE_3H_POST_POLYIC_INJ_DN | 188 | 46 | 17377 | 2626 |
UBL3,FEZ2,CYLD,PNISR,PPP1R2,GORASP1,HLA-E,RPS6KA1,TOR1AIP1,GADD45G,HABP4,KLHL18,YTHDF3,ASAH1,PSEN1,PPP1R16B,FAM8A1,TERF2IP,PTPN2,GRSF1,DAPK1,CLCN6,CDK12,MORC3,MOB4,IFRD1,CYTH1,TNFAIP3,MIOS,BAZ2A,PBXIP1,GALC,ZNF202,ESYT1,PLEC,OPTN,MTMR3,MKNK1,HHEX,CSK,TFE3,STAT6,LY75,RNF14,CSNK1D,N4BP2L2 |
| 4.955e-04 | -7.61 | GSE18281_CORTICAL_THYMOCYTE_VS_WHOLE_CORTEX_THYMUS_DN | MSigDB lists | GSE18281_CORTICAL_THYMOCYTE_VS_WHOLE_CORTEX_THYMUS_DN | 188 | 46 | 17377 | 2626 |
SEPHS2,MRPL9,PIGN,PLXNC1,PRKAA1,LAMTOR3,USP39,RACGAP1,PMF1,DCUN1D4,AHCTF1,SAR1A,PHTF1,INTS12,PARL,ZNF226,AQR,PTGES3,MOB1A,SPTSSA,CITED2,TRIM14,ABCC5,TMEM160,SRPK2,USO1,AGGF1,ZNF84,GALC,TACC1,ZNF500,RAD51AP1,CIRBP,RTF1,SRSF5,SHCBP1,TSR2,DTWD1,MKNK1,TPD52L2,DAP3,WNT5B,COX7A2L,MIA2,HMGB2,ZNF268 |
| 4.955e-04 | -7.61 | GSE9988_ANTI_TREM1_VS_VEHICLE_TREATED_MONOCYTES_DN | MSigDB lists | GSE9988_ANTI_TREM1_VS_VEHICLE_TREATED_MONOCYTES_DN | 188 | 46 | 17377 | 2626 |
RHOG,KIF3B,CYTIP,HECA,RPS6KA1,DYNLL1,SUMO2,RAC1,CCM2,KLF13,TWF2,MAPK14,GNB2,GIT2,KIAA1147,PAIP2,WDR44,FAM89B,GLTP,CORO1A,MAVS,ZNF710,TNRC18,CTDSP2,TACC3,SAP30,AMPD2,ORAI2,PPP1R9B,TRIM8,TACC1,MAP7D1,UBE4B,PTTG1IP,DHX57,MYO1F,TFEB,DDX17,CSK,STK38,ZDHHC7,STK11,WIPI2,PSAP,AKNA,MAPK1 |
| 4.955e-04 | -7.61 | GSE41867_NAIVE_VS_DAY15_LCMV_ARMSTRONG_EFFECTOR_CD8_TCELL_DN | MSigDB lists | GSE41867_NAIVE_VS_DAY15_LCMV_ARMSTRONG_EFFECTOR_CD8_TCELL_DN | 188 | 46 | 17377 | 2626 |
PPP1R37,UNK,GPR132,ZCCHC9,PHRF1,HMGXB3,FAM53C,SRGN,PTTG1,BRAP,EZH1,THRAP3,DNAJB1,SAFB2,PIP4K2A,RNF103,TMCC3,SUB1,NT5DC1,RCSD1,DDA1,BRI3,CRY2,CISD2,FAM76B,SLC26A2,LDLRAD3,CNPY3,GPD1L,ADCY7,PHF20L1,WBP2,KRAS,PACS1,MTMR12,BSDC1,TFEB,SERTAD2,PCM1,UAP1,KLHL15,ARRDC1,SRSF3,FAU,ZNF598,SMAD4 |
| 4.955e-04 | -7.61 | GSE17721_CTRL_VS_POLYIC_1H_BMDC_UP | MSigDB lists | GSE17721_CTRL_VS_POLYIC_1H_BMDC_UP | 188 | 46 | 17377 | 2626 |
ANXA6,UBN1,MDH2,SNX15,DHX8,BCL2L1,HEATR5B,NPLOC4,PIP5K1C,C14orf119,FAM192A,CEP104,RAP1A,ATG3,AKAP8,SOCS6,DNM2,ANAPC7,MRPL48,MRPL11,FRMD8,ATP6V0D1,NCOA2,PPIF,HMGN5,SIGMAR1,RBX1,NET1,ZNF574,WDR81,PNPLA8,SEPT7,RAB5B,HSPBP1,CHCHD1,LUC7L3,MAPK6,RPLP1,SEL1L,ZNF436,CEBPG,QRSL1,NCLN,TRIM32,YWHAH,CCNB2 |
| 4.969e-04 | -7.61 | EIF3B (eukaryotic translation initiation factor 3 subunit B) | protein interactions | 8662 | 79 | 25 | 17029 | 2761 |
EIF3L,STAU1,CYLD,EIF3D,BRCA1,MCM2,EIF3G,PARK7,PAIP1,EIF3H,EIF3A,EIF3K,MDM2,UPF1,ATP1A1,AHSA1,ZNF746,MSH2,TARDBP,MRPL40,EIF5,CD81,SMURF1,ATP6V0D1,CDC37 |
| 4.969e-04 | -7.61 | EXOSC10 (exosome component 10) | protein interactions | 5394 | 79 | 25 | 17029 | 2761 |
IMMT,EXOSC6,SUMO2,CIB1,CUL3,LSM8,KRAS,EXOSC9,BRCA1,FOXRED1,USP21,RPA1,CAND1,FERMT3,RPA2,EXOSC7,UPF1,HNRNPR,EXOSC1,TARDBP,UPF2,RUVBL2,IFI16,SSRP1,CDC5L |
| 4.969e-04 | -7.61 | MRPS7 (mitochondrial ribosomal protein S7) | protein interactions | 51081 | 79 | 25 | 17029 | 2761 |
FEZ2,HNRNPAB,RBM42,MRPS2,MRPS15,RPL6,TUFM,RPL8,CUL3,MRPL16,GUF1,ASF1B,RPL11,RPL23A,CAND1,ANKRD28,MRPL2,RPL17,GRSF1,MRPS27,MRPL54,TRMT10B,DUSP11,SNRNP70,MRM3 |
| 4.989e-04 | -7.60 | GEMIN2 (gem nuclear organelle associated protein 2) | protein interactions | 8487 | 62 | 21 | 17029 | 2761 |
COPA,STRN4,DHX9,RNPS1,CERK,DDX20,SNRPD3,GAR1,SRSF1,GEMIN5,CLK3,LSM6,SRSF4,GEMIN6,SRSF3,GEMIN4,SNRPG,SNRNP70,FBL,STRAP,GEMIN7 |
| 4.989e-04 | -7.60 | TSC1 (TSC complex subunit 1) | protein interactions | 7248 | 62 | 21 | 17029 | 2761 |
RPAP3,PLK1,TSC2,VHL,RPS6KA1,EZR,RRAGC,ATXN1,CCNB1,BECN1,MAPK14,RHEB,TSC1,PCM1,AXIN1,DAPK1,APPL2,CDKN1B,YWHAZ,RUVBL2,YWHAH |
| 4.989e-04 | -7.60 | RFC5 (replication factor C subunit 5) | protein interactions | 5985 | 62 | 21 | 17029 | 2761 |
RPAP3,RFC3,BRD4,CHTF18,XIAP,CUL3,NFATC2,RFC2,PSMC4,RPA1,CAND1,RPA2,RB1,PCNA,HUWE1,CENPJ,ZNF746,RUVBL2,COPS6,NMD3,CDC5L |
| 5.008e-04 | -7.60 | CNOT10 (CCR4-NOT transcription complex subunit 10) | protein interactions | 25904 | 38 | 15 | 17029 | 2761 |
PCM1,KLHL20,GPBP1L1,CENPJ,GADD45B,CNOT6,NUP153,USP22,CAPZA2,CNTROB,CNOT6L,CNOT11,LYN,PPP6R1,TOB1 |
| 5.008e-04 | -7.60 | GINS4 (GINS complex subunit 4) | protein interactions | 84296 | 38 | 15 | 17029 | 2761 |
GINS1,CSNK1G2,POLE,PPP1R2,MCM5,PRDX5,LAGE3,H2AFX,WDHD1,YWHAZ,AHCYL1,IGBP1,NCDN,SSRP1,LDHB |
| 5.008e-04 | -7.60 | PTPDC1 (protein tyrosine phosphatase domain containing 1) | protein interactions | 138639 | 38 | 15 | 17029 | 2761 |
FBXO3,PPP2CA,SDHB,DHPS,MAPKAPK3,HARS,YWHAZ,PTPDC1,CCNB1,MAPK1,YWHAH,PPP2R2D,CCDC28A,BBS12,MAPK3 |
| 5.008e-04 | -7.60 | TMCO1 (transmembrane and coiled-coil domains 1) | protein interactions | 54499 | 38 | 15 | 17029 | 2761 |
RPN1,ATP1A1,ATXN3,KIF14,RPS10,LAMTOR3,CYC1,SRSF5,MCM2,RAB1A,DUSP22,DDX39A,EYA2,ABCC1,CAND1 |
| 5.008e-04 | -7.60 | PPP1R10 (protein phosphatase 1 regulatory subunit 10) | protein interactions | 5514 | 38 | 15 | 17029 | 2761 |
TERF2IP,RPA2,HSPA4,PTEN,HUWE1,ABCF2,KCTD17,CTR9,WDR82,XRCC3,MPG,PRKACA,APP,ISG15,RPA1 |
| 5.008e-04 | -7.60 | ZEB1 (zinc finger E-box binding homeobox 1) | protein interactions | 6935 | 38 | 15 | 17029 | 2761 |
USP7,EWSR1,SMAD2,SYNCRIP,MPHOSPH8,DCAF15,DRAP1,USP42,VCPIP1,USP10,SMARCA4,SMAD1,ZMIZ1,USP53,USP13 |
| 5.011e-04 | -7.60 | FAM72 | interpro domains | IPR026768 | 4 | 4 | 18492 | 2768 |
FAM72B,FAM72C,FAM72D,FAM72A |
| 5.014e-04 | -7.60 | pancreas-carcinoid-endocrine_tumour-insulinoma | COSMIC cancer mutations | pancreas-carcinoid-endocrine_tumour-insulinoma | 29 | 12 | 17385 | 2587 |
GNAS,CDKN2C,FGFR3,NRAS,PTEN,VHL,STK11,KRAS,MEN1,SMAD4,HRAS,CDKN2A |
| 5.014e-04 | -7.60 | insulinoma | COSMIC cancer mutations | insulinoma | 29 | 12 | 17385 | 2587 |
GNAS,CDKN2C,FGFR3,NRAS,PTEN,VHL,STK11,KRAS,MEN1,SMAD4,HRAS,CDKN2A |
| 5.045e-04 | -7.59 | GO_ANTIGEN_PROCESSING_AND_PRESENTATION_OF_PEPTIDE_OR_POLYSACCHARIDE_ANTIGEN_VIA_MHC_CLASS_II | MSigDB lists | GO_ANTIGEN_PROCESSING_AND_PRESENTATION_OF_PEPTIDE_OR_POLYSACCHARIDE_ANTIGEN_VIA_MHC_CLASS_II | 89 | 26 | 17377 | 2626 |
KIF3B,DYNLL1,RAB7A,DCTN2,KIF15,KIF23,KLC1,RACGAP1,KIF2C,ARF1,AP1B1,KIF11,KIF2A,SEC31A,CTSS,KIF18A,SEC24C,DNM2,AP1M1,AP1S1,AP2B1,KIFAP3,KIF22,AP2S1,DYNC1LI2,DCTN1 |
| 5.045e-04 | -7.59 | GO_ANTIGEN_PROCESSING_AND_PRESENTATION_OF_PEPTIDE_ANTIGEN_VIA_MHC_CLASS_II | MSigDB lists | GO_ANTIGEN_PROCESSING_AND_PRESENTATION_OF_PEPTIDE_ANTIGEN_VIA_MHC_CLASS_II | 89 | 26 | 17377 | 2626 |
KIF3B,DYNLL1,RAB7A,DCTN2,KIF15,KIF23,KLC1,RACGAP1,KIF2C,ARF1,AP1B1,KIF11,KIF2A,SEC31A,CTSS,KIF18A,SEC24C,DNM2,AP1M1,AP1S1,AP2B1,KIFAP3,KIF22,AP2S1,DYNC1LI2,DCTN1 |
| 5.049e-04 | -7.59 | GO_CYTOSOLIC_RIBOSOME | MSigDB lists | GO_CYTOSOLIC_RIBOSOME | 108 | 30 | 17377 | 2626 |
RPS15,RPL29,RPL35,RPS2,RPLP2,RPL8,RPS10,RPL6,RPL38,RPL15,RPS24,EIF2AK4,RPL27A,RPS9,RPSA,RPL11,MCTS1,RPL23A,RPL36,RPL37,RPL32,RPL17,RPS27A,RPS14,EIF2D,RPLP1,RPL19,FAU,RPS26,RPL22L1 |
| 5.053e-04 | -7.59 | regulation of intracellular transport | biological process | GO:0032386 | 358 | 78 | 17256 | 2622 |
TXN,RAB11B,ANK3,PRKACA,LYN,SEC16A,MAPK14,RBM4,BCAP31,PARK7,PRNP,MIEF1,CDK5,RAB21,RAP1A,MDM2,ATP2A2,SP100,PIK3R2,PARL,NUP153,MAVS,LMAN1,ZC3H3,HTRA2,CHP1,PLK3,AKT2,EZR,NUTF2,EDEM2,TRIM28,USP36,IWS1,MAPK1,OAZ1,C2CD5,AAAS,SVIP,UBE2D3,PPP1R12A,TM9SF4,PRKAA1,DHX9,NUP54,CIB1,RAB23,PSEN1,SPAG5,KIF5B,PDCD10,NUS1,HUWE1,RIMS3,PTPN11,GTSE1,MDFIC,ATG13,PREB,PDPK1,TGFB1,GCC2,ATP5IF1,TCTEX1D2,RANGAP1,RHOT1,MAP2K2,SH3GLB1,MAPK3,NUCB1,PCM1,STX18,OAZ2,NUP62,RUFY3,PREPL,NUP58,RNF139 |
| 5.055e-04 | -7.59 | GSE32986_CURDLAN_LOWDOSE_VS_CURDLAN_HIGHDOSE_STIM_DC_UP | MSigDB lists | GSE32986_CURDLAN_LOWDOSE_VS_CURDLAN_HIGHDOSE_STIM_DC_UP | 183 | 45 | 17377 | 2626 |
TCF12,MCM10,UBN1,WDYHV1,CAST,RPS6KA1,C5orf30,KIF23,IKBIP,RGS2,FOXO3,ELMOD2,HMG20A,FBXO5,GNS,TFAP4,STARD9,KIF13B,PPP1R12C,CNPY4,PIKFYVE,TMEM8A,GPD1L,DNMT1,TPCN1,PACS2,CAMK2G,SRPK2,LONRF3,TMEM126B,ERLIN1,SLBP,CDCA2,ARID1A,ESYT1,BTBD1,ECH1,MAN2A2,SGSH,CSK,LUC7L3,HPS5,NDUFS5,RNASEL,OSGEPL1 |
| 5.055e-04 | -7.59 | GSE2770_IL4_ACT_VS_ACT_CD4_TCELL_2H_DN | MSigDB lists | GSE2770_IL4_ACT_VS_ACT_CD4_TCELL_2H_DN | 183 | 45 | 17377 | 2626 |
PRPF38B,SLC41A1,PPP1R15B,EIF3D,TRMT6,RAPGEF6,PA2G4,CLIC4,AHCTF1,EIF2S2,IARS,INPP5A,HUWE1,IL6ST,FOXN2,CRY2,TAP2,MAP3K14,ALDH18A1,AHCYL1,TOP1MT,MAML1,SRSF10,RBM15B,RYBP,SRSF11,IFRD1,PHF10,ERLIN1,PGS1,NOL8,MTMR12,USP22,USP36,MID1IP1,AXIN1,NLRC5,PTAR1,TBPL1,SLC16A1,ATF6,BEND3,NMD3,PFKP,SLC25A33 |
| 5.055e-04 | -7.59 | GSE36009_WT_VS_NLRP10_KO_DC_LPS_STIM_DN | MSigDB lists | GSE36009_WT_VS_NLRP10_KO_DC_LPS_STIM_DN | 183 | 45 | 17377 | 2626 |
NDUFS1,PNISR,ST13,KIAA0100,RRP15,SESTD1,RAF1,CSNK2A1,MYO9B,CHAC2,PIP4K2A,LYAR,PCNA,ADD3,STRBP,ZKSCAN1,INTS7,MBD2,PHTF1,RAB4A,TTC3,BCAP29,FAM76B,ILKAP,MYO5A,DDX28,TNFAIP3,FOXK1,LAP3,DENND1B,ABCF2,FAM133B,DNAJA1,RAB1A,BORA,IWS1,NSA2,KPNA1,PDLIM1,ARNTL,SMPD4,CCDC125,ZBTB11,MRPL3,GCSH |
| 5.055e-04 | -7.59 | GSE2770_UNTREATED_VS_TGFB_AND_IL12_TREATED_ACT_CD4_TCELL_2H_DN | MSigDB lists | GSE2770_UNTREATED_VS_TGFB_AND_IL12_TREATED_ACT_CD4_TCELL_2H_DN | 183 | 45 | 17377 | 2626 |
NDUFA5,SKA3,NPHP4,MRPL9,DEPDC1,LUZP1,PHB2,TPX2,KIF2C,ADPGK,NANS,MXD1,SAC3D1,CDKN2C,TBC1D22A,METTL14,PRC1,MAST2,UBE3B,ALDH18A1,FBXL19,PDLIM2,JMJD4,TRAFD1,ANKRD37,CDC123,PBK,WDR1,WDHD1,NUSAP1,CDCA2,SMC2,BRCA1,KRTCAP2,TRIM28,TMEM127,BIRC5,GADD45B,C4orf46,SMG9,CCNB2,USF2,DCAF5,DDB1,RNF114 |
| 5.055e-04 | -7.59 | GSE37532_TREG_VS_TCONV_PPARG_KO_CD4_TCELL_FROM_VISCERAL_ADIPOSE_TISSUE_UP | MSigDB lists | GSE37532_TREG_VS_TCONV_PPARG_KO_CD4_TCELL_FROM_VISCERAL_ADIPOSE_TISSUE_UP | 183 | 45 | 17377 | 2626 |
SRM,PDCD6IP,RWDD1,DEPDC1,UCK2,LAMTOR3,C5orf30,SDF2L1,CHAC2,SND1,PRPF18,MRPL50,PSMA6,TIMM23,AXIN2,TNPO2,KIF22,AHCY,CITED2,C12orf75,LRRC59,ZNF770,SYTL3,SAP30,BAK1,POU2AF1,KLF10,MTA2,ACSL3,ABCF2,FAS,AKAP1,MYO1F,GALNT2,SURF4,FAM110A,TBL3,NEIL3,GADD45B,TFDP1,AEN,SLC16A1,ASNA1,FKBP5,NAA20 |
| 5.055e-04 | -7.59 | GSE32986_UNSTIM_VS_GMCSF_STIM_DC_DN | MSigDB lists | GSE32986_UNSTIM_VS_GMCSF_STIM_DC_DN | 183 | 45 | 17377 | 2626 |
SRM,MAPRE1,FAM208B,RWDD1,AGRN,URB2,B4GALT5,JMJD6,NCKAP1,FBRS,ERH,SUB1,SNUPN,ATP2A2,NOL11,ZCCHC2,YIF1B,FBL,EIF5,S100A6,ABCC1,FDFT1,PPAN,TGFB1,B3GALT6,AGGF1,HEMK1,DDX24,SSR2,KDM1B,ODC1,EML4,DHX15,PHF6,RHOB,DOT1L,YIF1A,MAP4,DTX4,AEN,RGL1,TRAF5,ZNF598,LRP8,ADAM23 |
| 5.055e-04 | -7.59 | GSE8921_UNSTIM_0H_VS_TLR1_2_STIM_MONOCYTE_6H_UP | MSigDB lists | GSE8921_UNSTIM_0H_VS_TLR1_2_STIM_MONOCYTE_6H_UP | 183 | 45 | 17377 | 2626 |
ANKRD27,ANKRD13D,HNRNPAB,PLXNC1,NDUFB6,GORASP1,C1orf112,MRPS26,CDCA8,DNAJC24,HMGN3,NUF2,TMED3,GYG1,ARF1,NDUFS7,NRF1,PSMD1,CTNNBL1,TNFAIP8,BANF1,NDUFB9,TAGLN2,CYB5R1,TTLL12,S100A6,AMPD2,TIMM8B,FAM118B,LAP3,NSUN2,TMEM216,MRPS10,NUP155,CDC23,CYFIP2,MTR,STOML2,ALG3,MID1IP1,MTHFD2,PDLIM1,RUVBL2,EHD4,ESPL1 |
| 5.055e-04 | -7.59 | GSE17721_0.5H_VS_12H_PAM3CSK4_BMDC_DN | MSigDB lists | GSE17721_0.5H_VS_12H_PAM3CSK4_BMDC_DN | 183 | 45 | 17377 | 2626 |
PARP12,SHPRH,VTI1A,SIKE1,BECN1,GFM2,PNO1,MIS12,SPPL2A,CSDE1,RNF121,UBXN2A,ATP6V0B,MDM2,C18orf32,NUS1,NOL11,RNFT1,MECR,CAPZA1,ANAPC7,TTC17,LRRC59,CGGBP1,ACSL5,PHF10,POLR2G,NET1,PSMA1,USP10,SEPT7,MCFD2,RHOT1,GFER,RAB22A,TARS,CAT,CDKN2AIPNL,KPNA1,CDC27,AP1S1,ATE1,NDE1,UBE2C,PFKP |
| 5.055e-04 | -7.59 | GSE9006_TYPE_1_VS_TYPE_2_DIABETES_PBMC_AT_DX_DN | MSigDB lists | GSE9006_TYPE_1_VS_TYPE_2_DIABETES_PBMC_AT_DX_DN | 183 | 45 | 17377 | 2626 |
COMMD10,ASH1L,CDC40,GMFG,COPA,UGP2,TIA1,NIT2,GGPS1,ITGB5,PSMD1,GART,ASAP2,EIF2S2,RNFT1,TANK,METTL9,AHCYL1,STAT3,ACSL5,MOB4,PHF20L1,DENND1B,DENND4C,PSMA1,KCTD20,FBXO9,ARHGEF12,SLC17A5,KLF6,ARHGAP15,RHEB,SERF2,DUSP3,PTER,STX18,RBMS1,DHTKD1,MDH1,NCOA1,PDXK,RBPJ,SMAD1,PSMC1,PURA |
| 5.055e-04 | -7.59 | GSE26030_TH1_VS_TH17_RESTIMULATED_DAY5_POST_POLARIZATION_DN | MSigDB lists | GSE26030_TH1_VS_TH17_RESTIMULATED_DAY5_POST_POLARIZATION_DN | 183 | 45 | 17377 | 2626 |
TXN,TRAF7,GNPDA1,HMGXB3,ASAH1,CREBL2,DNAJB1,DCUN1D4,LCLAT1,PIP5K1C,CWC27,ATIC,PPP1R8,ADCY9,ZFYVE27,CTR9,ANAPC7,ALDH18A1,CPSF4,GNAI2,SGCB,CTDSP2,ARID4A,AMPD2,PDPK1,ABHD2,SEPT9,USP42,SUGP2,BMS1,MEF2D,MCM2,PTTG1IP,PRDX1,CYB5A,CCDC127,MAP3K4,SCARB2,TTC13,DSN1,HIPK2,ZC3H7B,KHSRP,RNASEL,ZMAT3 |
| 5.055e-04 | -7.59 | GSE46606_UNSTIM_VS_CD40L_IL2_IL5_3DAY_STIMULATED_IRF4HIGH_SORTED_BCELL_UP | MSigDB lists | GSE46606_UNSTIM_VS_CD40L_IL2_IL5_3DAY_STIMULATED_IRF4HIGH_SORTED_BCELL_UP | 183 | 45 | 17377 | 2626 |
CTU2,PDCD6IP,PIGN,FAM207A,C1orf112,TMEM109,MRPS26,AGPAT1,MYNN,FBXL6,ASAP2,NSRP1,ATG3,AP3S2,TCEA1,CLN6,POC5,DRAM2,LYPLA2,KDELR1,DCTN1,NAGPA,CSNK1G2,RBM42,DDX24,MIOS,AATF,ZMYND11,RNPS1,ZBED5,RCOR1,USP22,ZDHHC3,TWISTNB,RXRB,PPP2R5A,IARS2,VCPIP1,ZDHHC7,TMEM219,TCOF1,ARRB2,CHPF2,ANXA11,ATMIN |
| 5.059e-04 | -7.59 | PID_NFAT_3PATHWAY | MSigDB lists | PID_NFAT_3PATHWAY | 53 | 18 | 17377 | 2626 |
PPP3CA,CSNK2A1,NFATC2,PPP3CB,BCL2L1,MEF2D,CSNK1A1,PRKACA,MAPK14,MAPK3,FKBP1A,NFATC3,PPP3R1,YWHAZ,BCL2,KPNA2,CABIN1,YWHAH |
| 5.072e-04 | -7.59 | organic cyclic compound catabolic process | biological process | GO:1901361 | 503 | 104 | 17256 | 2622 |
ADA2,TRERF1,RPLP2,RBM8A,ADPGK,SND1,PAIP1,PABPC4,EDC3,RPL23A,MBD4,RPL11,TET3,CSDE1,EIF4A3,METTL14,DUT,EXOSC1,RNASEH2A,OGG1,ENPP4,RPL29,RPL35,EXOSC6,POLR2G,HPDL,RPL38,POLR2D,RNPS1,OGDH,RPS9,RPSA,RPL37,PPP2CA,HINT1,RPS27A,LSM6,RPS14,NT5C3B,RPLP1,DHTKD1,SCARB1,SMG9,NUDT11,RPS26,PFKP,GALK1,RPS15,RPS2,GSPT2,TATDN3,RPL15,PM20D2,THRAP3,PARN,CNOT11,EPHX2,METTL3,CNOT3,TUT4,NEIL2,PRPF18,PDXP,EXOSC7,RPL17,PPP1R8,PELO,DCP1A,RPL19,UPF2,AHCY,CNOT6L,PABPC1,SAMD4B,RNASEH2C,TRIR,NUDT4,RPL6,LDHA,RPL8,RPS10,RPS24,EXOSC9,PKM,PDE3B,RPL27A,PATL1,RPL36,HSPA1B,CNOT9,KPNA1,UPF1,RPL32,TATDN2,KHSRP,HMGB2,DNPH1,DDX5,CNOT6,GPI,TATDN1,PGAM1,YWHAH,NUDT3 |
| 5.080e-04 | -7.59 | GO_PROTEIN_FOLDING | MSigDB lists | GO_PROTEIN_FOLDING | 209 | 50 | 17377 | 2626 |
PPIB,DNAJC2,HSPH1,TXN,ST13,PRKCSH,DNAJB2,TMX4,MOGS,TMX3,DNAJC24,CSNK2A1,DNAJB1,FKBP2,QSOX2,GNB2,FKBP1A,CWC27,PPIG,PPIL2,TTC9C,RP2,PTGES3,LMAN1,PDIA6,GNAI2,PDCL3,TMX1,CDC37,PPIF,TXNL1,CCT2,MLEC,PPIE,DNAJA1,PPWD1,CCT8,FKBP3,HSPA1B,DNAJC10,PFDN5,HSPBP1,LTBP4,PFDN4,PDRG1,SIL1,FKBP5,ATF6,RUVBL2,CLU |
| 5.085e-04 | -7.58 | PSMC1 (proteasome 26S subunit, ATPase 1) | protein interactions | 5700 | 138 | 38 | 17029 | 2761 |
MIF4GD,CYLD,DCTN2,PMS2,JMJD6,UBQLN2,SDHA,KCMF1,APP,UBLCP1,RAD23A,PTPN2,RPN1,PSMD2,MDM2,PSMD1,PSMA6,HUWE1,UCHL5,RAD23B,ZNF746,NSFL1C,CDC5L,TXNL1,PSMA8,CUL3,PSMB7,PSMA1,TOPORS,BRCA1,PSMB9,PSMB3,PSMC4,ATP6V1D,PSMD3,PSMD8,MAP3K5,PDCD4 |
| 5.090e-04 | -7.58 | DUS3L (dihydrouridine synthase 3 like) | protein interactions | 56931 | 27 | 12 | 17029 | 2761 |
CDC16,TRMT6,EFTUD2,PRKAR1B,ACAT1,TCEA1,EIF2A,APP,RPRD1B,LMNA,EEF2K,GTF2F1 |
| 5.090e-04 | -7.58 | KCNC4 (potassium voltage-gated channel subfamily C member 4) | protein interactions | 3749 | 27 | 12 | 17029 | 2761 |
NAT14,HERC3,LEMD2,NUS1,TYW1,SLC25A51,ABCB10,ESYT1,DNAJB1,PDE3B,RHBDD1,NPLOC4 |
| 5.090e-04 | -7.58 | DEAF1 (DEAF1, transcription factor) | protein interactions | 10522 | 27 | 12 | 17029 | 2761 |
SP3,DEAF1,SUB1,TK1,PIN1,INTS1,RAD23B,IRF3,CREB1,HRAS,CDKN2A,CDC37 |
| 5.090e-04 | -7.58 | TTF1 (transcription termination factor 1) | protein interactions | 7270 | 27 | 12 | 17029 | 2761 |
NIFK,NFATC3,MDM2,BAZ2A,DGCR8,VPS26B,RPS14,RBM34,RNASEH2A,SMAD1,GPATCH4,CDKN2A |
| 5.090e-04 | -7.58 | RUNX3 (runt related transcription factor 3) | protein interactions | 864 | 27 | 12 | 17029 | 2761 |
MDM2,SMAD2,PHB2,PIN1,PML,SIRT2,RBPJ,SMAD1,CBFB,SMURF1,HDAC2,FANCI |
| 5.116e-04 | -7.58 | cellular response to peptide hormone stimulus | biological process | GO:0071375 | 266 | 61 | 17256 | 2622 |
MAX,AGTRAP,WDTC1,ATP6V1B2,PRKACA,LYN,AP3S1,ARID1B,GNB2,EEF2K,CFLAR,PTPN2,USF1,RAB8A,PDK2,ATP6V0B,CCNA2,MDM2,SHC1,PTEN,ADCY9,PIK3R2,ATP6V0A2,AHCYL1,CREB1,STAT3,ATP6V0D1,MYO5A,ADCY7,CDC5L,ATP6V1G1,TGFB1,PDPK1,CYFIP1,AKT2,PRKDC,DENND4C,GNG7,PRKAR1B,ATP6V0A1,RANGAP1,CDC6,SRSF5,MEN1,PKM,PDE3B,APPL1,MAPK3,SOCS7,EPRS,IDE,ATP6V1D,CSK,STAT1,ATP6V0C,ATP6V1C1,MAPK1,CPEB2,C2CD5,ATP6V0E1,SLC25A33 |
| 5.133e-04 | -7.57 | endosomal part | cellular component | GO:0044440 | 498 | 101 | 18223 | 2701 |
RAB14,SNX27,ANKRD27,CHMP2A,GNPNAT1,RAB11B,RAC1,VTI1A,MON1B,ZFYVE21,RRAGC,BECN1,RUFY1,STAM,APP,CD320,RAB21,RAB8A,ATP6V0B,WDR44,MTMR4,RAB35,RAB4A,CLCN6,ZFYVE27,AP2B1,MARCH2,TMEM9,TMBIM1,SNX25,SNX8,CLCN3,ATG9A,RAB7A,ATP6V0A1,CHMP2B,AP4E1,RAB5B,RAB22A,PLEKHF2,OPTN,CHMP4A,RPS27A,TAB2,GRIPAP1,CHMP4B,ATP6V0C,TICAM1,VPS4A,AP2S1,ATP6V0E1,STARD3NL,UBE2D3,GOLIM4,ANXA6,GGA1,CCZ1,HLA-E,CDIP1,RAB23,LAMTOR3,VPS45,ACAP1,GGA2,TMEM165,RAB11A,VPS25,SCYL2,HLA-A,TFRC,PIP5K1C,SPPL2A,CTSS,SNX18,ZNRF2,ATP6V0A2,PIKFYVE,ATP6V0D1,TPCN1,SNX2,RFFL,WDR81,ADRB2,APPL1,SPPL2B,RHOB,RMC1,PI4K2A,CTSL,HLA-B,SCARB2,OSBPL11,HGS,LAMTOR4,PML,APPL2,EHD4,WDR91,CHMP7,SNX14,VPS29 |
| 5.149e-04 | -7.57 | LEE_DIFFERENTIATING_T_LYMPHOCYTE | MSigDB lists | LEE_DIFFERENTIATING_T_LYMPHOCYTE | 178 | 44 | 17377 | 2626 |
ZNF207,PNISR,GMFG,TMBIM4,SRSF6,DLGAP4,KLF13,GTF3A,CDK13,HAUS2,C2orf68,VAV1,NUP210,TNFAIP8,RCSD1,NDUFS8,CORO1A,CNOT6L,TRIM14,RYBP,USP34,UBQLN4,CYTH1,SELPLG,BTG2,NLN,ITM2A,ARHGDIB,DCLRE1C,NFATC2IP,CYFIP2,ICAM2,PSMB9,STX16,ARHGAP15,EPB41,BRD2,ZC3H7B,FKBP5,AKNA,FBXL3,MZT2B,CBX4,FUBP1 |
| 5.149e-04 | -7.57 | GSE5679_PPARG_LIGAND_ROSIGLITAZONE_VS_RARA_AGONIST_AM580_TREATED_DC_UP | MSigDB lists | GSE5679_PPARG_LIGAND_ROSIGLITAZONE_VS_RARA_AGONIST_AM580_TREATED_DC_UP | 178 | 44 | 17377 | 2626 |
MIF,HIVEP3,GALK1,MIF4GD,TXN,TMEM41B,UQCR10,MAGED1,TRAK1,UCK2,PXMP2,HMGN3,ABHD14A,TFRC,SNRNP25,PDXP,CCP110,MRPL54,SPTSSA,CLTB,MYBL1,SENP1,IMPA2,UBE2QL1,RBM15B,NXT1,ANKRD37,LRBA,SEPT8,CCDC34,TMEM147,CHCHD6,MTHFD2,RBMX,NSMCE2,CORO1C,ITGB1,PPP1R11,PGAM1,MAPK1,MZT2B,SLC25A39,FAF1,STARD3NL |
| 5.149e-04 | -7.57 | GSE1460_INTRATHYMIC_T_PROGENITOR_VS_CD4_THYMOCYTE_UP | MSigDB lists | GSE1460_INTRATHYMIC_T_PROGENITOR_VS_CD4_THYMOCYTE_UP | 178 | 44 | 17377 | 2626 |
FGFR1OP,TXN,NQO1,UCK2,SLC29A1,STMN1,RMI1,GART,EIF4A3,FBXO7,NUP107,DAPK1,EFCAB11,RNASEH2A,IFT46,SEH1L,ABCC1,HEMK1,POLR2I,TIMP2,HMGN5,MRPL16,AURKB,UTP3,MTX1,EAF2,COMMD4,EIF4H,RFC2,PSMB3,RHEB,STOML2,ZMYM3,CHCHD3,CAT,RAD51C,ZNF282,PEX5,GALNT2,ETS2,NEIL3,TFDP2,IDH3B,PSMC1 |
| 5.149e-04 | -7.57 | GSE14000_4H_VS_16H_LPS_DC_TRANSLATED_RNA_UP | MSigDB lists | GSE14000_4H_VS_16H_LPS_DC_TRANSLATED_RNA_UP | 178 | 44 | 17377 | 2626 |
GMFG,NDUFB6,NDUFAF2,SRSF6,SDF2L1,ITGB5,LMNA,ASPHD2,ABL2,PRKD3,HOMER1,HUWE1,JAZF1,ATP13A3,HADHB,YIF1B,TTC3,AHCY,CYB5R1,ZNF710,GPD1L,ABHD2,CYFIP1,ERMP1,TACC1,PPT1,TIMMDC1,BTG2,EMB,NLN,ARHGDIB,ESYT1,RPS9,EIF3K,TSC1,MKNK1,PON2,DTX4,MEGF9,SCARB1,SPCS3,CLN3,BRWD3,ZC3HAV1 |
| 5.149e-04 | -7.57 | GSE45365_CD8A_DC_VS_CD11B_DC_DN | MSigDB lists | GSE45365_CD8A_DC_VS_CD11B_DC_DN | 178 | 44 | 17377 | 2626 |
HSPH1,TSC22D3,CDT1,C16orf87,RMI2,ASAH1,LACTB2,RGS2,PARN,POLR3K,CPNE3,HDDC2,TERF2IP,ANKRD26,SNRNP25,PDCD10,DPYSL2,SUCLG2,ANKRD13C,TMEM14C,MSH6,EBAG9,FOPNL,NQO2,BTG2,LYRM1,USP10,SHCBP1,CBFB,ANKRD46,FAS,DERL1,PON2,UAP1,RPL32,ZNF700,HNRNPH3,NSMCE2,AEN,ADAM9,ACADM,KLHDC4,PIEZO1,TATDN1 |
| 5.149e-04 | -7.57 | GSE36392_TYPE_2_MYELOID_VS_MAC_IL25_TREATED_LUNG_DN | MSigDB lists | GSE36392_TYPE_2_MYELOID_VS_MAC_IL25_TREATED_LUNG_DN | 178 | 44 | 17377 | 2626 |
NCOR2,NOP2,GPBP1L1,MAGED1,MOGS,GTF3A,SIRT2,B4GALT4,SLC12A9,EIF1B,SEC11A,TMEM69,ADD3,GATC,RPL17,PPIL2,TMEM8A,FBL,TTLL12,TRIM14,NIPSNAP1,ELOF1,USP34,CSTF1,ZNF524,NXT1,MBLAC2,KAT7,MRS2,ICMT,STX16,SUPT16H,TFEB,SEC31A,ZNF862,CDKN2AIPNL,PDRG1,AXIN1,ERGIC3,SIAH2,RUVBL2,AKNA,PPP5C,PDCD11 |
| 5.149e-04 | -7.57 | GSE8685_IL2_STARVED_VS_IL15_ACT_IL2_STARVED_CD4_TCELL_UP | MSigDB lists | GSE8685_IL2_STARVED_VS_IL15_ACT_IL2_STARVED_CD4_TCELL_UP | 178 | 44 | 17377 | 2626 |
CHMP2A,C9orf78,FEZ2,C19orf53,TMBIM4,RPLP2,TMX4,CHIC2,HMGN3,OAT,ATP6V1B2,RRP36,C14orf119,TMEM179B,ADD3,CTNNBL1,SAR1A,TIMM23,BDH1,TRMU,TAF5L,C8orf59,RNF19A,CLTB,FTSJ3,PCBP2,SMC4,SP3,CLPTM1,NEK7,ACSL3,HTATIP2,ADSL,TOR1AIP2,DNAJA1,MTMR3,GOLGA7,JAK1,PFDN4,SEL1L,FBXL3,WDR91,CHID1,HIGD2A |
| 5.158e-04 | -7.57 | ZF_RANBP2_2 | prosite domains | PS50199 | 23 | 10 | 12060 | 1670 |
EWSR1,MDM2,TAB2,NEIL3,NUP153,ZRANB2,FUS,ZRANB1,NPLOC4,RYBP |
| 5.166e-04 | -7.57 | TGF-beta Signaling Pathway | WikiPathways | WP366 | 133 | 36 | 5312 | 837 |
RAF1,RAC1,CUL1,MEF2A,UBE2I,ETS1,MAPK14,APP,SHC1,CDC42,UCHL5,PIK3R2,DCP1A,NUP153,ATF2,STRAP,TGFB1,RHOA,KLF10,RBX1,KLF6,MAP2K2,HGS,SMAD2,RBL1,E2F4,AXIN1,TFDP1,PML,PIAS2,ITGB1,ROCK1,CCNB2,SMURF1,MAPK1,SMAD4 |
| 5.176e-04 | -7.57 | NDUFS8 (NADH:ubiquinone oxidoreductase core subunit S8) | protein interactions | 4728 | 58 | 20 | 17029 | 2761 |
COX15,NDUFV2,NDUFS1,TIMMDC1,PHB2,NDUFA4,MTMR12,RAB1A,PSEN1,RAB5B,RHOT2,SDHA,NDUFS7,NDUFS4,SDHB,NDUFV1,NDUFA11,MPV17,CYC1,NDUFS5 |
| 5.176e-04 | -7.57 | RUFY1 (RUN and FYVE domain containing 1) | protein interactions | 80230 | 58 | 20 | 17029 | 2761 |
SNX8,TELO2,RAB14,NLN,TGOLN2,PMF1,RAB3IP,AP3S1,RUFY1,CCT8,GIT2,COPB2,FAS,UTP25,HSPBP1,TIMM23,RAB4A,PIAS2,RUFY3,TUBB |
| 5.176e-04 | -7.57 | SPTA1 (spectrin alpha, erythrocytic 1) | protein interactions | 6708 | 58 | 20 | 17029 | 2761 |
ERCC1,ADD1,MYBL2,EZR,SMARCA4,PLEC,RPSA,LMNA,RPA1,XRCC5,RPA2,HNRNPA2B1,VASP,SHC1,RAD23B,XPA,XRCC2,PML,USP11,ABI1 |
| 5.176e-04 | -7.57 | NDUFB8 (NADH:ubiquinone oxidoreductase subunit B8) | protein interactions | 4714 | 58 | 20 | 17029 | 2761 |
TIMMDC1,PHB2,RAB7A,NDUFA4,WBP1,TOMM40,RAB1A,SPPL2B,COPG2,NDUFS7,NDUFS4,SSR1,RPN1,ATP1A1,NDUFV1,NDUFA11,NDUFB9,NDUFS5,LMAN1,ATP6V0D1 |
| 5.194e-04 | -7.56 | BURTON_ADIPOGENESIS_5 | MSigDB lists | BURTON_ADIPOGENESIS_5 | 113 | 31 | 17377 | 2626 |
PPIF,MRPS2,PHB2,MDH2,MRPL12,MRPS26,TMEM97,PSMA1,CYCS,TOMM40,BCAP31,DNAJB9,ABHD5,ZNRF2,TIMM23,PRDX3,TIMM17A,CRAT,MAPK6,DBI,MRPL34,ACADM,GPI,CYC1,PRADC1,TALDO1,PDIA6,LRRC59,MTX2,TOB1,PPA1 |
| 5.211e-04 | -7.56 | skin-scalp-malignant_melanoma-desmoplastic | COSMIC cancer mutations | skin-scalp-malignant_melanoma-desmoplastic | 33 | 13 | 17385 | 2587 |
FGFR3,CYLD,NRAS,TNFAIP3,TSC2,NF1,CIC,SMARCA4,NOTCH2,PBRM1,ARID1A,HRAS,CDKN2A |
| 5.212e-04 | -7.56 | ATPase regulator activity | molecular function | GO:0060590 | 44 | 16 | 17224 | 2647 |
DNAJC2,HSPH1,ATP5IF1,DNAJB2,TOR1AIP1,DNAJC24,TOR1AIP2,DNAJB1,DNAJA1,DNAJC10,TSC1,HSPBP1,AHSA1,RAB4A,SIL1,FNIP2 |
| 5.225e-04 | -7.56 | PID_MYC_PATHWAY | MSigDB lists | PID_MYC_PATHWAY | 25 | 11 | 17377 | 2626 |
PPP2CA,MAX,PPP2R5A,KAT2A,PIN1,AXIN1,PML,RUVBL2,TAF12,SUPT7L,CDKN2A |
| 5.225e-04 | -7.56 | GO_SPINDLE_MIDZONE | MSigDB lists | GO_SPINDLE_MIDZONE | 25 | 11 | 17377 | 2626 |
PLK1,CTDP1,PKP4,KIF18A,CDC42,KIF14,CDCA8,CDC6,RACGAP1,AURKB,APP |
| 5.225e-04 | -7.56 | GO_STRAND_DISPLACEMENT | MSigDB lists | GO_STRAND_DISPLACEMENT | 25 | 11 | 17377 | 2626 |
RAD51C,PALB2,RAD51AP1,XRCC2,RMI2,TOP3A,XRCC3,BRCA1,BLM,RMI1,RAD51D |
| 5.235e-04 | -7.55 | V$MYC_Q2 | MSigDB lists | V$MYC_Q2 | 173 | 43 | 17377 | 2626 |
IVNS1ABP,ZFP91,SCYL1,UBXN1,RRAGC,EBNA1BP2,TAF6L,RLF,STMN1,PABPC4,CSDE1,ATP6V0B,PA2G4,YBX1,TAGLN2,ALDH18A1,CFL1,NUDC,AMPD2,B3GALT6,NRAS,POLR2L,HNRNPF,LDHA,PFKFB3,ESYT1,KRTCAP2,EIF3A,HMGN2,EPB41,ADSS,PTPRF,ALDH3B1,CCDC6,HNRNPH3,HPS5,SLC16A1,LRP8,B4GALT2,SLC25A33,RAB3IL1,RHEBL1,ATXN7L2 |
| 5.254e-04 | -7.55 | ADP binding | molecular function | GO:0043531 | 36 | 14 | 17224 | 2647 |
ATP1A1,COQ8A,PRPS2,MYO18A,MSH2,TAP1,MYH9,GLUD1,RUVBL2,MYO9B,PPP5C,PKM,MSH6,MIEF1 |
| 5.257e-04 | -7.55 | PFDN6 (prefoldin subunit 6) | protein interactions | 10471 | 42 | 16 | 17029 | 2761 |
RPAP3,PFDN5,EWSR1,SPATA2,PFDN4,POC1A,GMFB,TNPO3,PRPF4,RUVBL2,PPP6R2,IGBP1,DCAF5,PPP6R1,GNB2,B4GALT2 |
| 5.257e-04 | -7.55 | TOB1 (transducer of ERBB2, 1) | protein interactions | 10140 | 42 | 16 | 17029 | 2761 |
CORO7,RPS6KA1,CNOT11,APP,CNOT3,CHAF1A,DTL,CNOT9,SMAD2,ATE1,CNOT6,CNOT6L,SMAD1,MAPK1,PABPC1,SMAD4 |
| 5.257e-04 | -7.55 | POLH (DNA polymerase eta) | protein interactions | 5429 | 42 | 16 | 17029 | 2761 |
USP7,DYNLL1,CENPF,WBP2,BRCA1,PCBP1,APP,AHNAK,PCNA,MDM2,RAD18,PALB2,RPS27A,DHX16,ACTB,TUBB |
| 5.257e-04 | -7.55 | Cul3 (cullin 3) | protein interactions | 26554 | 42 | 16 | 17029 | 2761 |
COPS8,PHF20L1,RBX1,CUL3,KLHL18,KCTD20,BTBD1,CAND1,GOLGA2,CORO1C,PPP3R1,TAF12,KLHL42,BTBD10,COPS6,SAP30 |
| 5.258e-04 | -7.55 | BET1L (Bet1 golgi vesicular membrane trafficking protein like) | protein interactions | 51272 | 11 | 7 | 17029 | 2761 |
GORAB,USO1,COPA,GOSR1,APP,STX18,TMEM216 |
| 5.258e-04 | -7.55 | HELQ (helicase, POLQ like) | protein interactions | 113510 | 11 | 7 | 17029 | 2761 |
RAD51C,DHX16,RAD51D,FANCI,XRCC2,RPA1,DHX9 |
| 5.284e-04 | -7.55 | positive regulation of mRNA metabolic process | biological process | GO:1903313 | 66 | 21 | 17256 | 2622 |
POLR2G,BTG2,AGO2,YTHDF3,THRAP3,CCNB1,METTL3,CDC73,PAF1,UPF1,HNRNPR,RBMX,METTL14,KHSRP,TRA2B,SNRNP70,CNOT6L,TOB1,PABPC1,ZC3HAV1,PRPF19 |
| 5.307e-04 | -7.54 | pancreas-carcinoma | COSMIC cancer mutations | pancreas-carcinoma | 15226 | 2316 | 17385 | 2587 |
HECA,ZBTB10,ABCC10,HEXB,TGOLN2,CCNL2,FBXO22,EEF2K,THAP4,RAD23B,ATP13A3,DNM2,ZNRD1,FTSJ3,USP34,CCDC57,ERCC1,NRAS,EHMT1,KIF15,HNRNPF,WDHD1,MIER2,DIDO1,RAB22A,SMAD2,RPS27A,MYO18A,OGT,MPV17,COX5A,SMAD1,ZNF75A,ANXA11,SLC25A33,ZNF720,SEC61G,GGA1,MUM1,CCZ1,TRIO,RAB23,KCTD17,HAUS4,EIF2AK4,APH1B,PARN,CDC73,ATG4A,TMEM179B,ERV3-1,PDXP,SMC3,C4orf3,MVP,NUP85,PPP6R1,PABPC1,NSUN4,PPA1,IFRD1,AGGF1,FOXK1,RBM42,GTPBP4,MAP7D1,ELK1,EIF4H,RDH11,MAGED2,KPNA1,ETS2,TYW5,WIPI2,RUFY3,PDLIM5,ACSF2,EXOC3,STARD7,VTI1A,SLC35B2,INO80E,RCOR3,LCLAT1,CPNE3,KIAA1147,RBM23,ZNF420,AHCTF1,TBC1D22A,TBC1D14,GMEB1,NSFL1C,SEPT11,GPD1L,ZC3H3,ARL5A,PDCL3,SNX8,ERMP1,EID1,IDH3A,POLR2D,HTATIP2,MEF2D,TMEM147,GSTCD,TANC1,MAT2A,VPS26B,CORO1C,NSMCE2,CAMKMT,PPP5C,PITRM1,TUBB,COMMD10,ZNF445,HABP4,CCM2,FLOT1,BTN3A1,ATG2B,ABHD14B,GOLM1,HUWE1,ZNF260,NAA50,ANXA5,LTN1,UBE3B,NAP1L4,ZNF710,ST8SIA2,RPL22L1,SPTAN1,STAU1,TCTEX1D2,DDX24,TACC1,MRS2,HEBP2,LLPH,RAB3IP,TTC33,PICALM,SH3BP5,SLC19A1,ACOX1,FAM3C,AEN,PARP10,YWHAH,THAP5,GPATCH4,FAM129A,TRIM11,YTHDC2,SNX15,RBM8A,NENF,SND1,RUFY1,TRIM65,ZER1,KRR1,RAB8A,NUP210,NT5DC1,NOC2L,EIF5,TACC3,RYBP,VPS13B,PTPN18,MIOS,SNRPB,MBLAC2,CDC6,PBRM1,ODC1,USP21,TRAM2,FBXO28,BCL7C,ARRDC1,ADAM9,DVL1,NUMB,ZNF564,C1orf74,CTU2,PARP12,ZCCHC9,CENPF,LAMTOR3,CHCHD2,NCKAP1,RSAD1,TNS3,SUB1,RINL,SSBP3,KIF13B,MBD2,XPA,AHCY,RBM3,GLE1,MRPL48,LRSAM1,HDHD2,NTPCR,NSDHL,AMD1,CAMSAP1,ZNF761,METTL22,STYXL1,APPL1,BBS12,ANKRD46,SDHB,PCM1,GALNT2,TMEM168,NLRC5,BTBD10,MYO9A,CCNB2,USP7,GLT8D1,RPLP2,SUCLG1,ARID2,TMX4,SLC2A1,ATP6V1B2,PCBP1,LYN,VAV1,MRPL50,PSMA6,ZNF473,ZNF302,BRPF3,TARDBP,BCAP29,CTDSP2,PRPF19,KDM3B,MND1,CLCN3,BIRC3,RAB7A,ANKRD33B,PPIE,CHMP2B,VDAC1,EIF3H,GLOD4,IDE,DHX16,UHRF2,CHMP4B,XRCC3,PARD3,BCL2L12,C19orf53,KLHL21,PDAP1,CDCA8,TMX3,GTF3A,ARF1,SLC12A9,TUBGCP2,HOMER1,WBP1L,POLR1B,RNF5,PPAN,RHOA,RPRD1A,BTAF1,TOP3A,ARHGEF12,PCGF1,DDX23,RAB18,ATP6V1D,L3MBTL3,FAM110A,NEIL3,CTBS,BBX,IMPDH1,TAF12,NR2F2,HIPK3,IFI16,TXN,NUP188,H2AFZ,PNISR,PRKCSH,USP39,UBE2I,SLC25A37,ASPHD2,ZNF428,RAB4A,TRA2B,SUCLG2,TAF5L,CISD2,ZNF800,CDC5L,SGCE,OSBP2,NSUN2,USP22,CLNS1A,EIF3A,ZMYM3,DOT1L,IWS1,ANKRD10,WAS,KIF18B,TPP2,ZMAT3,FAM72C,PRPF38B,RECQL,C9orf78,EWSR1,GADD45G,RRM1,ACAP1,B4GALT1,FAM136A,SUPT7L,TMEM165,CNOT3,NPLOC4,SPAG5,WDR48,RTKN,CEP104,EXOSC7,KLHL5,LRRC8D,MSH2,PIGG,FBXL7,OSTF1,MRPL40,TNRC18,SYTL3,FAM171A1,APOL1,GCC2,PRIM2,ELL2,RDH10,MFNG,GORASP2,CAPZA2,ADRB2,CCT8,MTR,PHF6,PFDN5,SLCO4A1,TTC13,GOLGA2,RBMX,MED15,PIAS2,APPL2,SAMD8,NUDT3,CDKN2A,ZNF511,ATXN3,RAF1,KIAA0232,C2orf49,EPM2A,CCNA2,MTMR4,BRI3,TP53BP2,AQR,RBM12B,ILKAP,CDK12,SAP30,BRD4,DRAP1,NARF,LRRC8A,ELP4,ABHD11,PKMYT1,ASB13,SERP1,TRIM28,SUPT16H,EIF3K,CHMP4A,CBWD1,ATF6,XRCC4,PRPF4B,ADAM23,NDUFS1,DEPDC1,MECP2,SECISBP2,HMG20A,WWP2,SLC25A36,JAKMIP1,CCNK,DNAJC8,AXIN2,CITED2,JMJD4,ANKRD37,KAT2A,ADSL,PACS1,BMS1,KCNQ1,OTUD3,ARSK,MACF1,KIF11,KLF6,COMMD4,SMAP2,FADD,MYO1F,CBX3,TMEM127,PPP1R11,DDX5,WDR62,TAF6,ESPL1,DDB1,DEF6,IPO4,FAM83G,UBL3,NAT9,LYRM4,UBE2Q1,PTP4A3,BRIX1,MRPL19,SF3B2,PCYOX1L,CDC42,SYNM,GOT2,JAZF1,HADHB,RPF2,SLC35C2,CNNM3,CARM1,SRPK2,WDR41,LARS,ZCCHC10,CCDC138,LRBA,TMEM216,KMT2C,OGFR,PRPSAP1,ASF1B,MAN2A2,EIF4ENIF1,U2SURP,MIA2,ZNF268,VPS4A,ATP6V0E1,PPP1R2,PM20D2,XPNPEP3,RGS2,LYAR,POLR2I,TRAFD1,SUGP2,GBA,EIF2A,SYVN1,DAPK3,ARHGAP15,MASTL,UAP1,FN3KRP,YWHAZ,CTSA,TMEM14A,TOB1,TSEN15,ADNP2,TCF12,PRKAB1,MDH2,SMARCA4,ORC1,RRN3,UBXN2A,IARS,CD3EAP,KIF14,EXOSC1,CS,CLTB,CSTF1,POU2AF1,UBQLN4,PGGT1B,SELPLG,SMU1,ATXN1,GLO1,OGDH,BICD2,CADM1,EDEM2,HERPUD2,TOLLIP,FANCE,MBD3,PDHX,RPS9,ALKBH6,SURF4,DUS3L,ARNTL,ANP32E,FKBP5,CCDC125,ABCA1,PDCD2L,GCLM,RAE1,DCTN2,NUP54,CHIC2,PAWR,MXD4,DCUN1D4,PIP4K2A,XPR1,FERMT3,KIF5B,KLHL20,SEC24C,RRBP1,ARHGEF2,ANP32A,LDLRAD3,C12orf75,STAT3,MYO5A,NIPAL3,TXNL1,PHF20L1,FAM49B,TMEM39A,ATP2C1,RFFL,COG1,RCOR1,PRMT2,TFEB,LEMD2,SERF1B,UPF1,ELMO1,ZC3H7B,DTX4,ZMIZ1,TERF1,HRAS,CCDC93,FGFR1OP,TMED7,PIGQ,CNTROB,PPP1R16B,MIS12,TTC9C,PDS5B,NUP153,SENP1,PGAP2,TMEM115,PLEKHM3,DCUN1D5,PLEKHF2,BRMS1,PWWP2B,TRIM47,WDR11,AXIN1,SMG9,LONP2,NDUFV2,PHF23,CERK,SLC4A2,EZH1,ITGB5,LMNA,DDX56,EIF2S2,SLC38A5,FOXN2,CARS2,PRRC2A,C16orf72,RB1CC1,ZMYND11,PGS1,MYBL2,UHRF1BP1,MPG,MATR3,CYB5A,NCDN,POLR2J,SETD3,TEX30,PTAR1,CNOT6,NDE1,EGLN1,ZNF207,ANKRD27,PPP1R37,ABCA3,SARNP,IVNS1ABP,MON1B,RMI2,TMEM97,NIT2,NUF2,ZNF267,TMEM161B,KTN1,APP,PRKD3,CLUAP1,ATP2A2,UTP18,GRSF1,ZCCHC2,RNF19A,FAM76B,CLN6,TMEM9,GCC1,RNF169,ADCY7,ATP6V1G1,ENPP4,RNPS1,CDCA2,FKBP3,GPR137,DDX17,CHCHD3,PEX5,CDC16,HIPK2,MBOAT1,TICAM1,PDXK,ZBTB11,ANXA6,TMBIM4,GMCL1,UBE4A,IL21R,ETS1,WRB,ZNF92,PNO1,CAPN2,ADD3,TTLL12,TPCN1,TMX1,HNRNPM,MFSD12,LDHB,PPP3CA,POLK,MTMR12,PDE3B,KIF18A,CCDC6,WNT5B,MAPK6,LY75,SLC25A19,RGL1,PSAP,WDR76,IGBP1,FAF1,SNAPIN,COX15,AGRN,THOC1,GNPDA1,GPBP1L1,PPP1R15B,CSNK2A1,EBNA1BP2,GIT2,BIRC2,ATPAF1,DLG5,ABL2,XRCC2,ZFYVE27,MCMBP,PTPRK,CDC37,METTL1,HARS,GMFB,ESYT1,ANLN,RAB5B,RHEB,DPYSL3,TBC1D17,TONSL,NRM,NAGLU,ACTB,ZNF45,CTCF,DOCK11,CRLF3,ASXL2,NUS1,SLC27A4,MDFIC,MAML1,NQO2,UTP15,EIF2AK1,EIF4G2,ZDHHC3,MOSPD3,ITPRIPL1,CDC27,SNAP23,TBPL1,PRMT7,KCTD7,NDUFA5,CYLD,UGP2,COPE,ZADH2,GGPS1,RAD23A,ABRACL,ATP6V0B,PDK2,STRBP,DUS4L,MRPL34,PDCD2,SAP30L,SLC39A9,CLPTM1,RPL29,RPL35,BTG2,DNAJC9,MTMR6,NFATC2,KDM1B,ARL5B,USP36,CCDC127,MRPL2,ATP1A1,PSMD3,CEP55,DNAJC17,ZNF436,NCOA1,SLC25A39,ZC3HC1,ZNF146,ATXN7L2,CDC40,GOLIM4,SMAP1,RRP15,DAP,GNE,SMC6,ARFIP2,NKRF,CHAC2,BZW2,WRNIP1,SS18L1,CENPM,PTGES3,CAMK2G,MLEC,ZNF202,PPWD1,FAM50B,RHOT2,NEU1,TPD52L2,GOLGA7,TWSG1,PGRMC1,GLG1,FAM126A,RPS6KC1,UBE2C,PPCS,NDUFB6,TMEM41B,ZDHHC8,PLXNA1,CCNB1,SLC20A1,COMMD6,POLR3K,ASAP2,SNUPN,CNPY4,PLCL2,TFG,SEH1L,ATG9A,PBK,MKI67,DDX20,AMDHD2,SLC17A5,GALNT7,CCNF,FOXRED1,RBM47,PTER,WDR4,DHTKD1,TRAF5,HDAC2,PWWP2A,HSPH1,LIME1,MAPRE1,CHTF18,KIF23,SLC35B1,NOTCH2,PMF1,JMY,FKBP1A,NDUFAF6,SLC31A1,SNX18,ATIC,ATP6V0A2,PIKFYVE,RNF135,LPCAT1,EEF1D,TMED2,PHF10,SIGMAR1,PIP4K2C,RIT1,PLEC,KDM3A,SF3A2,FAS,EPRS,ZNF777,TMEM54,QARS,TCOF1,CABLES1,NRBP1,DNMT3A,RWDD1,CKLF,TRIP10,SF3B1,SUZ12,RPS6KA1,RAC1,GPR89A,OLA1,GNB2,FLAD1,APLP2,KDM2A,TNPO2,CDKN1B,TALDO1,ATP13A1,RFC3,MAPRE2,ERF,CUL3,SLBP,KIAA1586,H2AFV,GAR1,POLG2,DHX57,NSA2,HSPA4,MRPL55,JAK1,GOLGA8A,TBL3,SEL1L,H2AFX,KLHDC4,B4GALT3,PDCD11,ATMIN,POLQ,POU3F2,OTUD5,NCOR2,PKP4,SCAMP3,BABAM1,SLC25A12,BLM,TMCC3,GTF2F1,RPL17,CRAT,AHSA1,PRC1,UPF2,COPS7B,SLC38A10,CNOT6L,CNPY3,UBE2M,IFT46,TMEM160,TSHZ1,ZFP64,DENND4C,DENND1B,WDR18,ILF3,LRRC1,RHOT1,MARK2,TSR2,ECH1,PRDX1,NUCB1,GNA12,FBXO21,C1orf131,PRDX3,PFDN4,HNRNPH3,TFDP1,STX18,KHSRP,ASNA1,CPEB2,BYSL,S100PBP,MIB2,PTMS,NOP2,UBN1,DCAF15,NF1,ALKBH5,MOGS,UBE2Z,TAF6L,BECN1,MAPK14,SNAPC4,RNF103,BCAT2,MBD4,METTL14,ZNHIT6,IMPAD1,RCSD1,PHTF1,SRI,KIF22,ZBTB22,NFU1,OGG1,TRIM14,COPS8,FYTTD1,TRIM8,SOX4,ABHD5,UBTF,CXXC4,PAF1,SPATA2,PQBP1,IARS2,ATXN2L,GALNT10,STARD3NL,RPS15,PIGN,AGTRAP,CIB1,SRRT,ZNF449,CAPZA1,GLTP,KIFAP3,BCL2,N4BP2,HP1BP3,VOPP1,THNSL1,ISG15,CAND1,C22orf46,GNAS,TSC1,RBM25,ZFP90,NANP,RBBP4,ZBTB24,SMARCD1,MBD1,WASF2,MMACHC,TOMM20,IFI27L1,GNPNAT1,MPHOSPH8,HNRNPUL2,CHD1,MEAF6,CCDC50,AKAP8,PARL,RPN2,CHTOP,F2R,FAM3A,SCYL3,TMEM14C,ABI1,HTRA2,MOSPD1,RLIM,FAM172A,ZNF500,PSMB7,NLN,WIPF1,BOLA1,BUD13,NDUFB1,PEF1,EIF3G,BTBD1,TAB2,TULP3,WDR59,CANT1,SCARB1,GAS2,USP11,SMURF1,TSPAN5,PPP2R2D,CDS2,MAGEH1,MRPL42,EYA1,CDK2AP2,MRPS26,LETMD1,KLF13,RGS1,HDDC2,MAN1A1,FBXO5,GART,TANK,PELO,BRD7,MRPL11,SAMD4B,ZDHHC18,GTF3C6,POLR3GL,WDR81,MEN1,ZNF407,MFN2,COX8A,ZRANB2,SRSF3,MBD6,IDH3B,TATDN1,ATP6V1C1,TSC2,LACTB2,CMTM6,RBM4,ZNF275,ANKRD39,RPL23A,CDKN2C,NAPG,USF1,DNAAF2,MECR,AP1M1,UPRT,CRY2,ECD,TIPARP,LRRC59,RHBDD2,MGAT5,BAK1,ZNF559,RHOBTB3,GABPA,WBP1,NUTF2,ARF4,GINS4,KRIT1,BOLA3,AHNAK,RAD18,PDRG1,RNASEL,OAZ1,PDCD4,SMNDC1,NXT2,HIVEP3,KIAA0100,CLSPN,RHOC,DHX9,PDCD7,PSMD9,HAUS2,COPB2,CD59,TFAP4,RIMS3,MEGF8,FBXO7,EFTUD2,CPSF4,MRPL21,LUC7L2,EIF3L,MTA2,TYW1,USP10,ITM2A,SSR2,MTX1,SFXN5,FNTA,PDLIM1,TXNDC16,TMEM159,MRPL3,ALS2,TRIM41,KARS,NQO1,POC1A,ANK3,PTTG1,TPX2,TBC1D13,GLRX3,REPS1,CBWD5,ABHD16A,FBXL6,SH3BP1,MTA1,UBA5,CLCN6,INTS12,RPRD1B,SZRD1,CPNE1,SEC61B,POLR2L,FAM118B,GOPC,E2F3,CIRBP,RPL38,CRNKL1,PFKFB3,GORAB,RAB1A,GIGYF1,TMEM184C,PPP2CA,KIF2A,CCDC14,LSM6,RNF38,SNRPG,CENPBD1,DMWD,USP13,MZT1,ZFP91,TRMT6,WDR5,SLC25A43,PMVK,IFT27,NEIL2,RRP36,RPA2,PSMD2,CLIC4,PDCD10,CBWD2,COQ4,ITGB8,ARHGEF1,FBXL19,GTF2H2,TTPAL,UTP20,GPS2,CD81,TMEM131,WDR13,FANCI,PAPOLA,CREM,FANCL,TET3,GLIS2,IL6ST,INTS1,SLC44A1,MTPN,ASB6,PLK1,SEPT9,CELSR2,RBX1,APH1A,RAD51AP1,CKAP2L,PSMG1,EAF2,IL12RB1,KRTCAP2,LUC7L,LSG1,ALG3,TRIM4,AGPAT2,CHD3,ZNF367,E2F4,PRPF4,KPNA2,BEND6,CLN3,DNAJC30,FAM208A,NGLY1,POT1,MYL12B,CCDC137,RMND5A,HJURP,PHB2,DNAJB2,FAM53C,NKD2,SDC2,KLC1,CDK13,ADCK5,COX4I1,DNAJB1,RAB6A,ARID1B,C1GALT1,MLX,UBE2Q2,CCP110,ZNF746,ARL6IP1,CTR9,NIPSNAP1,ABHD2,DCAF8,ACSL3,MAP4K3,ARMC8,RBM38,NMT2,IRF5,HAUS8,MBIP,ORMDL2,COX7A2L,ZDHHC7,SIL1,FAM122A,DTD1,UNC13C,SART1,TRAF7,NDUFAF2,TOR1AIP1,ZFYVE21,TM9SF3,RRAGC,ZNF121,OIP5,NRF1,WDR44,PPME1,EFCAB11,RPAP1,CABLES2,LMAN1,AHCYL1,TOP1MT,STRAP,SPSB3,ZNF583,SNX25,ARHGAP17,POLR2G,KIAA0040,ZNF780B,PPT1,NUP155,MRPS14,RHBDF2,SUGP1,RBL1,FASTK,UBXN2B,STK38,AP1S1,SLC22A23,H3F3A,CHID1,SMAD4,RAD51D,SLC30A9,CMAS,NADSYN1,HMGN3,NCAPG,SCYL2,FZD6,HERC3,GTPBP3,CTSS,ORC3,RNLS,YTHDC1,ACP2,HMGN5,CSRP1,METTL5,ABCF2,TUFM,RANGAP1,PNPLA8,HAGH,API5,ZFR,SEC23IP,E2F1,TMEM219,USP20,RBPJ,PDCD6IP,MAX,GXYLT1,LUZP1,ADAM10,CXXC1,TSC22D3,AP3M2,CUL1,GYG1,NANS,OAT,MYEF2,ANKRD26,PA2G4,NOL11,FIZ1,ZNF200,MARCH2,SLC26A2,SRP72,KLF10,LACTB,CBFB,RFC2,RAB2B,PRIM1,MAP3K4,HHEX,LUC7L3,RPS14,MAP4,MRPL27,BTF3,PTPDC1,NMD3,CCDC59,PTOV1,COX5B,DNAJC5,SCOC,ANKH,VAV2,PRKAA1,C16orf87,TATDN3,DLGAP4,PXMP2,PRPF39,PSEN1,ZNF79,PDXDC1,VPS25,NDUFS7,C12orf10,FAM192A,RPN1,LHX8,ARPC5,ZNRF2,TPST1,DAPK1,PIK3IP1,CYC1,SOCS5,FDFT1,PIGT,EMB,ZNF574,EXOSC9,ARID1A,PTTG1IP,C9orf40,FXR1,GOSR1,MAP2K2,TWISTNB,AKAP1,XRCC5,HMGN2,PI4K2A,CAT,DERL1,HSPBP1,ARAP1,USP32,FAM83D,CABIN1,SMPD4,GPI,CYTIP,TP53RK,REPS2,RAB11B,UROD,SLC39A13,POMP,BCL2L1,NUDT19,DECR1,RALB,ADCY9,LPIN2,MRPS27,SOCS6,TTC3,RNASEH2A,CFL1,ANKLE2,CDC123,OAF,EDF1,ERC1,ANKZF1,RAD51C,ZNF282,DSN1,DDOST,HINT1,DGCR8,SAFB,HAGHL,FTSJ1,RWDD4,LMBR1,NCLN,BEND3,EYA2,DYNC1LI2,MANBA,SLC41A1,B4GALT5,FAM76A,TKT,CBLL1,ARGLU1,LANCL1,POFUT1,FAM8A1,HEATR5B,HLA-A,EBP,RFWD3,NDUFA2,FJX1,FUT8,BTF3L4,PTPN11,MRPL54,FEM1B,RPL19,CNN2,NDUFA3,MTX2,MSH6,RFXANK,FBXO9,GUF1,RPL32,ZHX1,OAZ2,NDUFS5,WDR91,POLA2,ZNF76,COPA,UQCR10,PHRF1,HMGXB3,ABCB10,MAP1LC3B,DST,RAB35,SIVA1,GPATCH1,TCEA1,DRAM2,DEAF1,TRAPPC13,SNRNP200,LAP3,NCK1,VHL,SREK1,ARHGDIB,PITPNB,HSPB11,BRWD1,PPM1G,SH3GLB2,BAZ1B,ACBD4,STK11,CLU,CHEK2,ZSWIM3,TSTD2,CHPT1,MRPL13,DCAF5,CAPN1,UBE2D3,NSMCE4A,PPP1R12A,ZCCHC8,GORASP1,UBXN1,EPN1,PCSK7,THRAP3,QSOX2,TTF1,PRPF18,NUP205,CHKA,DTL,MED10,ZRANB1,SLC12A2,ATP6V0D1,CSNK1G3,CREG1,NUDT4,RPL6,SLTM,EVC2,KLHL15,SIAH2,SLC16A1,EHD4,SNRNP70,C11orf1,APOL2,N4BP2L2,CHMP2A,CORO7,FEZ2,UCK2,PMS2,EXT2,MXD1,USP5,SAP130,NVL,CYB5R1,EBAG9,RNF25,PCGF6,FAM72B,PON2,HNRNPR,STAT6,HPS5,MAPK1,BRD9,TMEM33,DNAJC2,TRIP12,SHPRH,SCYL1,VPS45,MYO9B,GFM2,SPPL2A,FASTKD3,FGFR3,MZT2A,PPIG,ZDHHC13,TMEM99,H2AFY,NDUFS8,ATG13,ERI3,FBL,SLC35A1,FRMD8,MICAL3,TGFB1,ELOVL5,HEMK1,TIMMDC1,HELB,PSPC1,MIER1,SCFD2,NDRG3,CDK11A,MEGF9,ACAT1,CENPT,PLOD3,RAB3IL1,ZSWIM6,RAB14,ADD1,KDM4A,MRPS15,XIAP,DHX8,GLUD1,ANKRD23,CDK5,CALM2,PSMD1,NEK6,NSRP1,RABGAP1L,SRSF4,KCNAB2,PCBP2,MLST8,PLK3,ZNF672,HSDL1,MRPL43,MCL1,PPFIA3,SMC2,ICMT,SLC50A1,LIMK1,ZNF689,PRDX5,ATE1,MLYCD,ST3GAL2,ATP6V0C,FBXL3,E2F2,PFKP,AAAS,DDX42,SSRP1,MRPL9,MRPS2,STRN4,TOP2B,ZNRF3,TMED3,DDRGK1,RAVER2,GNS,INTS7,INPP5A,MCM5,PHF14,ZNF326,UBE2QL1,NAGPA,ETV3,TSPAN31,DHX29,TEX10,MAN1B1,RPS10,CBFA2T2,ABCF1,RHOB,LRRC14B,DTWD1,PTPRF,SCARB2,OSBPL11,CCDC86,DUSP3,SLAIN1,HEXA,RNF139,SNX14,ZNF296,TRERF1,UBR2,CHD1L,ACTR3,WDTC1,MYH9,CREBL2,NIPA2,PRKACA,SAFB2,ANKIB1,STAM,ARL6IP6,RAB21,SP100,ZKSCAN1,DDA1,NUP107,ANKRD13C,MAVS,CEP63,ATF2,RBM15,DCTN1,SHOC2,MAP4K4,WBP2,ATP6V0A1,NUSAP1,DNAJA1,NDUFA7,TAF2,C19orf54,SEC61A1,RPLP1,WDR7,CBLN2,FUS,LRP8,COIL,LRCH1,GALK1,ZNF786,RPS2,SESTD1,TRAK1,JMJD6,SIKE1,AKT1S1,KRI1,FBXO3,ERH,GATC,NDUFB4,PPP1R8,PRDM4,GTSE1,GEMIN6,DCP1A,SGCB,IMPA2,NUDC,PDPK1,TK1,GUK1,TNFAIP3,GALC,ZNF512,KIAA0930,MRPS10,DDX39A,RPA1,ZNF180,ZNF862,KEAP1,POLE,TATDN2,PITX1,CAPN7,LRPPRC,PML,USF2,ANAPC4,SRM,DDX47,MCCC1,CDC42SE2,S1PR2,CDIPT,SEC16A,SSR1,LIN9,PCNA,ZNF639,TRMU,ETV6,PIK3R2,PPCDC,TXLNA,FAM86C1,MYBL1,CCAR1,MRPL32,ABCC5,BAZ2A,PBXIP1,TLK1,MRPL12,EZR,LNX2,LRP5,BRCA1,PRKRA,STX16,EPB41,OPTN,SEPT1,SOCS4,QRSL1,PIEZO1,OSGEPL1,GLCCI1,NUDT11,NAA60,SEPHS2,LZTR1,RACGAP1,PPP3CB,B4GALT4,RLF,RAPGEF6,RB1,VASP,MED8,VMP1,MEA1,TIMELESS,ALDH18A1,TMEM8A,PREB,ABCC1,TRAPPC9,AACS,MEMO1,KRAS,RTF1,UBE4B,NFATC2IP,LY6E,ARPC1A,ZNF174,PSMC4,GOLGA4,SYNCRIP,PALB2,PRPS2,NIPA1,RNF114,FOXM1,MRPL39,XAB2,DUSP22,COMMD8,RPL11,CSDE1,MDM2,CORO1A,MINPP1,METTL9,POC5,DVL2,GM2A,PSMA8,COQ10B,CPOX,SLC26A6,CYP20A1,PRPF3,TXNL4A,RPSA,DNAJC10,ZNF700,SCAP,TIMM17A,TOMM6,FAU,LTA4H,AP2S1,USP53,INTS2,CTDP1,MIF4GD,ARID5A,SUMF1,GGA2,CSNK1A1,AP3S1,TFRC,PTPN2,IRF4,STARD9,NDUFV1,SLC1A4,CWC27,SLC35B4,DDX31,ABCD1,RPAP3,CNTN5,SNX2,ZMYM5,CHCHD6,BSDC1,CDKN2AIPNL,FBXO41,KPNA4,BIRC5,TFE3,SNAP29,CDCA7L,PKD2,ACADM,CHMP7,SAT2,GCSH,ZNF496,TMEM109,TAP1,YTHDF3,NHLRC3,IKBIP,ELMOD2,KIFC1,DBNDD1,CYB5RL,PARPBP,CDC25B,PRADC1,DNMT1,NOL12,ORAI2,USO1,AKT2,NOL8,GNG7,AURKB,MCFD2,SLC25A5,MAK16,STT3A,TMED10,PSMD8,EIF2D,ITGB1,PTPN7,UQCRH,ARRB2,RTN3,ZNF598,SVIP,DDX58,WSB2,PPIB,MUT,GMFG,NDUFA4,MAN2B1,METTL3,CFLAR,NDUFS4,RNF121,MEX3C,KLF16,HDAC7,DAD1,BDH1,PCYT2,GNAI2,ANKHD1,MORC3,TERF2,KCTD20,SEPT8,DCTD,PKM,TOMM40,PATL1,ADSS,SERTAD2,ZFP92,NSF,DCK,ERGIC3,ACLY,LPCAT4,VCPIP1,PPP6R3,PPP6R2,MAP3K5,YY1,CDK2,RNF14,ZC3HAV1,URB2,EIF3D,MAGED1,KLHL18,ADPGK,SLC25A44,AP1B1,SDHA,PHC2,CRKL,TERF2IP,ZNF75D,SHC1,UCHL5,NAA35,CDKN2AIP,CCT2,MKLN1,LYRM1,GALK2,CDC23,SHCBP1,AP4E1,PRDM11,VEZF1,PPP2R5A,ACYP1,STAT1,PPA2,TRIM32,RHEBL1,C1orf112,TCF3,MRI1,BRAP,AGPAT3,MYNN,SDF2L1,SPR,RAB11A,REEP5,FOXO3,MAD2L2,CCDC28A,RBM17,MAT2B,PTEN,CENPJ,TAGLN2,OSTC,CREB1,NCOA2,PACS2,SMC4,RNASEH2C,NEK7,PARP4,TBRG4,ANAPC2,YIF1A,SGSH,HGS,TTLL4,SLC38A7,MFAP1,CCDC69,BRWD3,ESYT2,SKA3,NPHP4,UBE2E2,HNRNPAB,PLXNC1,ST13,TMEM184B,DNAJC24,ZNF107,SLC29A1,KIF2C,AGFG1,SIRT2,USP48,SNRPD3,UBQLN2,FKBP2,CUTC,EDC3,UBLCP1,ZNF804A,RAP1A,THADA,EIF4A3,AP3S2,ATG3,DPYSL2,PPP1R12C,AKR1B1,JOSD1,NDUFB9,RP2,TTC4,TECR,ARID4A,FGFR1OP2,TIMM50,TDP1,DPM1,FOPNL,SLC16A7,SLC25A22,WDR82,STK17B,DHX15,CHAF1A,GEMIN5,COPS6,SASS6,RPS26,PSMC1,SLC12A7,TBC1D12,TM9SF4,UFC1,MED13L,TIA1,MEF2A,EPHX2,PITHD1,RHBDD1,NFATC3,BUD31,ZNF335,YBX1,KNTC1,UBE3C,ACAD8,ZNF189,ALDH9A1,KDELR1,TSTA3,CIC,OXR1,SEPT7,NAP1L1,NSMF,ODF2,EXOC4,NUP62,PITPNA,KIAA1328,NAA20,PTDSS1,MZT2B,PDSS2,C7orf26,TMEM106C,IMMT,ASH1L,CHERP,WDYHV1,PLAGL2,IRF3,TWF2,PAIP1,FARSA,ANKLE1,SAR1A,SCAMP4,APOOL,PDIA6,ACSL5,TOR1AIP2,AZI2,GFER,RAD54B,TMEM41A,DAP3,ZNF317,AKNA,REEP4,CBX4,KIF3B,GOLPH3L,SH2D3A,CASP6,TOR3A,SRGN,DBF4,MFSD10,SAC3D1,CTNNBL1,TTC17,SLC25A1,GINS1,PAQR6,CSNK1G2,TELO2,HMGN1,ADAM17,NASP,ASPM,PPP1R21,PRKAR1B,SYMPK,TARS,SNRPA,MAPK3,HLA-B,PLAA,ATAD2,ZNF330,OSBPL8,KBTBD7,PREPL |
| 5.313e-04 | -7.54 | GSE12366_PLASMA_CELL_VS_NAIVE_BCELL_UP | MSigDB lists | GSE12366_PLASMA_CELL_VS_NAIVE_BCELL_UP | 168 | 42 | 17377 | 2626 |
CCNC,CYTIP,LIME1,GOLPH3L,SEC61G,CREBL2,HMGN3,SLC35B1,RGS2,SDHA,FAM8A1,LMNA,COPB2,IRF4,EIF2S2,SLC1A4,NDUFB4,MEGF8,UBA5,RPN2,KNTC1,MAST2,OSTC,LMAN1,TMEM39A,DENND1B,AACS,BTG2,PARP4,SSR2,EAF2,RAB2B,DAPK3,CXXC4,MAGT1,CCDC14,TPP2,ERGIC3,PQBP1,SPCS3,GLCCI1,GEMIN7 |
| 5.314e-04 | -7.54 | CDKN2AIP (CDKN2A interacting protein) | protein interactions | 55602 | 54 | 19 | 17029 | 2761 |
POLR2I,ADD1,CUL3,HNRNPF,BRCA1,CHAC2,RPA1,UTP25,RPA2,PTPRF,MDM2,KPNA1,TMED10,NEIL3,ECPAS,HNRNPDL,SLC12A2,CDKN2A,CDC5L |
| 5.314e-04 | -7.54 | STK25 (serine/threonine kinase 25) | protein interactions | 10494 | 54 | 19 | 17029 | 2761 |
MOB4,UBE2D3,GORASP1,STRIP1,DYNLL1,TAOK1,STRN4,MTMR6,SIKE1,APP,USP36,PPP2CA,PDCD10,GOLGA2,EIF4A3,CAB39,YWHAZ,ZNF598,FGFR1OP2 |
| 5.314e-04 | -7.54 | RBM17 (RNA binding motif protein 17) | protein interactions | 84991 | 54 | 19 | 17029 | 2761 |
CYLD,CHERP,SF3B1,CUL3,LNX2,CSNK2A1,PPP3CB,SF3A2,DHX15,SF3B2,SUGP1,GOLGA2,U2SURP,CEP55,PPP1R12C,XRCC3,SMURF1,CDK2,CDC5L |
| 5.314e-04 | -7.54 | SMU1 (SMU1, DNA replication regulator and spliceosomal factor) | protein interactions | 55234 | 54 | 19 | 17029 | 2761 |
SRSF11,SNRNP200,FAM172A,RAE1,CUL3,RNPS1,LSM8,SRSF5,MATR3,SRSF1,MFAP1,LUC7L3,SAFB,EFTUD2,YBX1,MRFAP1L1,SRSF3,IFI16,SRSF10 |
| 5.314e-04 | -7.54 | VSIG1 (V-set and immunoglobulin domain containing 1) | protein interactions | 340547 | 54 | 19 | 17029 | 2761 |
INTS2,DEPDC1,NF1,URB2,CYP20A1,UBE4A,XPO7,AP3S1,RUFY1,SFXN5,XPR1,MFN2,UTP20,FANCL,INTS7,TNPO2,TNPO3,TIMELESS,TMEM160 |
| 5.314e-04 | -7.54 | Brwd3 (bromodomain and WD repeat domain containing 3) | protein interactions | 382236 | 54 | 19 | 17029 | 2761 |
USP7,RFC3,RPL35,MRPS15,RBX1,MRPL43,RFC2,TARS,RPL11,RPL36,LYAR,UBTF,MRPL2,BRWD1,RPL17,MRPL21,WDR91,MRPL13,DDB1 |
| 5.314e-04 | -7.54 | EEF1E1 (eukaryotic translation elongation factor 1 epsilon 1) | protein interactions | 9521 | 54 | 19 | 17029 | 2761 |
KARS,COX15,LARS,NAT9,RNASEH2C,RAF1,RPL15,DNAJA1,MCM2,ATP6V1B2,VDAC1,RPL27A,RPL36,RPL23A,HNRNPA2B1,EPRS,IARS,HUWE1,QARS |
| 5.314e-04 | -7.54 | NUBP2 (nucleotide binding protein 2) | protein interactions | 10101 | 54 | 19 | 17029 | 2761 |
PTMS,C9orf78,RHOA,GNPDA1,UCK1,H2AFV,PAIP1,PABPC4,PPP2CA,CDK5,THADA,STAT6,RAD23B,TARDBP,ZRANB2,IGBP1,HEXA,DCTN1,NUDC |
| 5.314e-04 | -7.54 | TOP3A (DNA topoisomerase III alpha) | protein interactions | 7156 | 54 | 19 | 17029 | 2761 |
NF1,MECP2,METTL2A,RMI2,CDC6,BLM,DCUN1D4,RMI1,CDC73,RPA1,SDHB,RPA2,MAP3K4,PALB2,FAAP100,MSH2,CCDC69,MRPL21,TERF2 |
| 5.323e-04 | -7.54 | JUP (junction plakoglobin) | protein interactions | 3728 | 143 | 39 | 17029 | 2761 |
MRPL9,CYLD,ST13,PHB2,WDYHV1,DYNLL1,UBXN1,MYH9,B4GALT1,GMCL1,NENF,SLC25A44,ATP6V1B2,PSEN1,SDHA,BIRC2,CDC73,CSDE1,PTEN,MCM5,MSH2,TARDBP,RBM3,PTPRK,BIRC3,RAB7A,RAD51AP1,ILF3,PLEC,BRCA1,MCM2,DPYSL3,XRCC5,CAT,PTPRF,HSPA4,AXIN1,IARS2,CDK2 |
| 5.323e-04 | -7.54 | NFATC1 (nuclear factor of activated T cells 1) | protein interactions | 4772 | 143 | 39 | 17029 | 2761 |
RECQL,MDH2,SMARCA4,UBE2I,CSNK1A1,MAPK14,WDR48,SMC3,NUP210,NEK6,DNAAF2,CREB1,ATF2,SMARCE1,PPP3CA,MKLN1,FOXK1,NEK7,TUFM,NFATC2,ARID1A,SMC2,FXR1,ARMC8,CBFB,RFC2,RPA1,ZMYM3,XRCC5,MTHFD2,PML,PPP3R1,OGT,RBPJ,BEND3,HDAC2,IFI16,CSNK1D,SMARCD1 |
| 5.323e-04 | -7.54 | LRRK2 (leucine rich repeat kinase 2) | protein interactions | 120892 | 143 | 39 | 17029 | 2761 |
PPP1R12A,RAB11B,CHD1L,ACTR3,AGO2,RAC1,RAB11A,CALM2,CDC42,STRBP,ARPC5,AKAP8,DAPK1,CAPZA1,GNAI2,DVL2,CDC37,TK1,RHOA,RAB7A,PRKDC,NFATC2,DNAJA1,CAPZA2,PLEC,RAB5B,FADD,MYO1F,EPRS,GNA12,HSPA4,L3MBTL3,ACTB,YWHAZ,DVL1,H3F3A,YWHAH,MYL12B,TUBB |
| 5.335e-04 | -7.54 | NAXE (NAD(P)HX epimerase) | protein interactions | 128240 | 17 | 9 | 17029 | 2761 |
RHOA,MAPK6,MEMO1,H2AFX,ARMT1,CTSA,NUTF2,SDHA,FADD |
| 5.335e-04 | -7.54 | MEX3B (mex-3 RNA binding family member B) | protein interactions | 84206 | 17 | 9 | 17029 | 2761 |
UBE2D3,SNUPN,SUZ12,YWHAZ,YWHAH,PABPC1,PIP4K2A,SMAD4,NUDT3 |
| 5.335e-04 | -7.54 | Sacm1l (SAC1 suppressor of actin mutations 1-like (yeast)) | protein interactions | 83493 | 17 | 9 | 17029 | 2761 |
RPN1,COPA,DDOST,COPE,ATP5F1B,COPG2,COPB2,SMC4,CDC5L |
| 5.340e-04 | -7.54 | GO_NCRNA_TRANSCRIPTION | MSigDB lists | GO_NCRNA_TRANSCRIPTION | 80 | 24 | 17377 | 2626 |
INTS2,GTF3C6,POLR2I,RPRD1A,POLR2G,POLR2L,POLR2K,ELL2,POLR2D,GTF3A,SRRT,SNAPC4,POLR2A,GTF2F1,CCNK,POLR2J,INTS7,CD3EAP,INTS1,RNASEK,INTS12,POLR1B,TAF6,RPRD1B |
| 5.345e-04 | -7.53 | protein-lysine N-methyltransferase activity | molecular function | GO:0016279 | 61 | 20 | 17224 | 2647 |
ASH1L,KMT2E,SUZ12,CXXC1,EHMT1,NSD3,WDR82,EZH1,MEN1,KMT2C,WDR5,METTL22,DOT1L,IRF4,SUV39H2,KMT5C,KMT5A,SETD3,CAMKMT,KMT2B |
| 5.348e-04 | -7.53 | HMGA1 (high mobility group AT-hook 1) | protein interactions | 3159 | 97 | 29 | 17029 | 2761 |
NCOR2,EWSR1,HNRNPAB,OLA1,CSNK2A1,RACGAP1,PCGF1,UBE2I,PCBP1,CHD1,APP,PA2G4,DNAJC8,EIF2S2,SYNCRIP,CWC27,PPP1R8,HIPK2,BANF1,HMGB2,UPF2,CREB1,CDK2,ATF2,HNRNPDL,PCBP2,HDAC2,TERF2,SRPK2 |
| 5.363e-04 | -7.53 | STOM (stomatin) | protein interactions | 2040 | 129 | 36 | 17029 | 2761 |
NDUFS1,PHB2,RAC1,SLC2A1,DNAAF5,MYH9,TM9SF3,LANCL1,NUP205,EBP,RAB8A,ATIC,EI24,TNPO3,RNF26,FGFR1OP2,HNRNPM,PIGT,SIGMAR1,RAB7A,ERLIN1,ILF3,ADRB2,VDAC1,CCT8,CIP2A,STOML2,SUGP1,EPRS,PON2,SURF4,ERGIC3,RUVBL2,PTDSS1,IPO4,STARD3NL |
| 5.363e-04 | -7.53 | SMAD9 (SMAD family member 9) | protein interactions | 4093 | 129 | 36 | 17029 | 2761 |
RMND5A,MBD1,TRIP12,XAB2,TWNK,SF3B1,SECISBP2,MAN2B1,ARID1B,PABPC4,DST,HUWE1,RRBP1,CTR9,AFF1,UBQLN4,FTL,KAT2A,BTG2,CAMSAP1,LRP5,PLEC,SMAP2,EVC2,SMAD2,PSMD8,QARS,VCPIP1,SIL1,RBMS1,ACTB,PSAP,SNRNP70,TERF1,TOB1,SMAD4 |
| 5.370e-04 | -7.53 | GO_PEPTIDYL_LYSINE_TRIMETHYLATION | MSigDB lists | GO_PEPTIDYL_LYSINE_TRIMETHYLATION | 18 | 9 | 17377 | 2626 |
TET3,SUV39H2,SETD3,ZNF335,OGT,CTR9,RTF1,BEND3,ARID4A |
| 5.370e-04 | -7.53 | GO_LRR_DOMAIN_BINDING | MSigDB lists | GO_LRR_DOMAIN_BINDING | 18 | 9 | 17377 | 2626 |
POLR2J,AATF,KRAS,PAWR,STK11,PMF1,ERC1,DAPK3,CDC5L |
| 5.370e-04 | -7.53 | BIOCARTA_PTEN_PATHWAY | MSigDB lists | BIOCARTA_PTEN_PATHWAY | 18 | 9 | 17377 | 2626 |
PDPK1,PDK2,SHC1,PTEN,ITGB1,CDKN1B,MAPK1,FOXO3,MAPK3 |
| 5.375e-04 | -7.53 | SAP30BP (SAP30 binding protein) | protein interactions | 29115 | 46 | 17 | 17029 | 2761 |
EWSR1,THOC1,DHX8,CSNK2A1,CDK11A,SF3A2,LMNA,RBM17,MLX,GOLGA2,HUWE1,FUS,TERF1,DDB1,SAP30,DCTN1,TERF2 |
| 5.375e-04 | -7.53 | FARSA (phenylalanyl-tRNA synthetase subunit alpha) | protein interactions | 2193 | 46 | 17 | 17029 | 2761 |
CYLD,CUL3,CUL1,GORAB,MCM2,SDHA,TARS,WWP2,CDC42,HNRNPR,ZNF746,OGT,USP32,XRCC3,USP11,ECPAS,EEF1D |
| 5.375e-04 | -7.53 | MRPS18B (mitochondrial ribosomal protein S18B) | protein interactions | 28973 | 46 | 17 | 17029 | 2761 |
KARS,EXOSC6,EWSR1,HNRNPAB,MRPS2,MRPS26,CUL3,MYH9,PARK7,CAND1,RB1,DAP3,QARS,MRPS27,RBM3,TRMT10B,FUS |
| 5.375e-04 | -7.53 | CDK20 (cyclin dependent kinase 20) | protein interactions | 23552 | 46 | 17 | 17029 | 2761 |
NTPCR,TRAFD1,RAF1,RHOT1,ERC1,MAGED2,CDK5,ATP1A1,PSMD1,KEAP1,AHSA1,PPP5C,RBBP4,CFAP20,CDK2,CDK12,ZNF146 |
| 5.375e-04 | -7.53 | ENO3 (enolase 3) | protein interactions | 2027 | 46 | 17 | 17029 | 2761 |
PPIB,CYLD,TXN,TKT,FKBP2,PKM,ATP5PF,APP,FKBP1A,CAT,HINT1,DUT,AKR1B1,GPI,TAGLN2,PGAM1,GPX4 |
| 5.375e-04 | -7.53 | FSCN1 (fascin actin-bundling protein 1) | protein interactions | 6624 | 46 | 17 | 17029 | 2761 |
MIF,VHL,TKT,RAB1A,MCM2,ANLN,PCBP1,DNAJB9,PRDX1,GNAS,SEPT11,CNN2,SMURF1,ATF2,CDK2,IMPA2,FUBP1 |
| 5.375e-04 | -7.53 | PPP6C (protein phosphatase 6 catalytic subunit) | protein interactions | 5537 | 46 | 17 | 17029 | 2761 |
USP7,PRKDC,AURKB,BRCA1,PCGF1,SRRT,ANKRD28,TAB2,ZNRF2,ACLY,ARHGEF2,MOB1A,PPP6R2,PPP6R3,IGBP1,PPP6R1,CSNK1D |
| 5.387e-04 | -7.53 | ZMYND11 (zinc finger MYND-type containing 11) | protein interactions | 10771 | 50 | 18 | 17029 | 2761 |
SNRNP200,DYNLL1,ZMYND11,GBA,EZH1,UBE2I,SRSF1,SMAD2,ETS2,ZHX1,PPIG,EFTUD2,SRSF4,H3F3A,CDK2,TRAF5,PABPC1,SRSF10 |
| 5.387e-04 | -7.53 | SCFD1 (sec1 family domain containing 1) | protein interactions | 23256 | 50 | 18 | 17029 | 2761 |
STAU1,USO1,MRPL9,VPS45,TMEM216,ATP6V0A1,USP22,OGDH,MCM2,GOSR1,EVC2,NSF,SNAP23,STX18,MPV17,MRPL40,MRPL13,MRPL32 |
| 5.387e-04 | -7.53 | ETF1 (eukaryotic translation termination factor 1) | protein interactions | 2107 | 50 | 18 | 17029 | 2761 |
FGFR1OP,LARS,GSPT2,PSMA1,RTF1,NCKAP1,DNAJB1,PPP2CA,GEMIN5,UPF1,EIF2S2,KEAP1,SLC38A7,CORO1C,RNF26,PABPC1,PDCD4,NUDC |
| 5.410e-04 | -7.52 | cellular response to dsRNA | biological process | GO:0071359 | 53 | 18 | 17256 | 2622 |
DDX58,CGAS,AGO2,DHX9,FLOT1,IRF3,PRKRA,METTL3,SRRT,TUT4,HNRNPA2B1,SMAD2,RALB,DGCR8,ZC3H7B,PQBP1,MAVS,SMAD1 |
| 5.425e-04 | -7.52 | GO_RIBOSOME_ASSEMBLY | MSigDB lists | GO_RIBOSOME_ASSEMBLY | 49 | 17 | 17377 | 2626 |
PPAN,RPS15,DDX28,RPS10,RPL6,RPL38,BMS1,EIF2A,BRIX1,RPSA,RPL11,RPL23A,NIP7,RPS14,RPF2,MRPL11,NSUN4 |
| 5.429e-04 | -7.52 | REACTOME_SIGNALING_BY_WNT | MSigDB lists | REACTOME_SIGNALING_BY_WNT | 62 | 20 | 17377 | 2626 |
PSMA8,PSMB7,PSMA1,FRAT2,CUL1,PSMB9,CSNK1A1,PSMD9,PSMB3,PSMC4,PPP2CA,PSMD2,PSMA6,PSMD1,PPP2R5A,RPS27A,AXIN1,PSMD3,PSMD8,PSMC1 |
| 5.429e-04 | -7.52 | REACTOME_CYCLIN_E_ASSOCIATED_EVENTS_DURING_G1_S_TRANSITION_ | MSigDB lists | REACTOME_CYCLIN_E_ASSOCIATED_EVENTS_DURING_G1_S_TRANSITION_ | 62 | 20 | 17377 | 2626 |
MAX,PSMB7,PSMA1,CUL1,PKMYT1,PSMB9,PSMD9,PSMB3,PSMC4,PSMD2,RB1,PSMA6,CCNA2,PSMD1,RPS27A,PSMD3,PSMD8,CDKN1B,CDK2,PSMC1 |
| 5.443e-04 | -7.52 | Transport of the SLBP independent Mature mRNA | REACTOME pathways | R-HSA-159227 | 34 | 14 | 10287 | 1696 |
NDC1,NUP188,NUP210,RAE1,NUP107,NUP54,NUP62,NUP155,NUP153,NUP85,NUP58,AAAS,NUP205,SEH1L |
| 5.466e-04 | -7.51 | PECE_MAMMARY_STEM_CELL_UP | MSigDB lists | PECE_MAMMARY_STEM_CELL_UP | 128 | 34 | 17377 | 2626 |
KARS,RPS2,TXN,RPLP2,SEC61G,MANBA,DYNLL1,NACA,RPL15,SMARCA4,COX4I1,CDC42SE2,RPL23A,C8orf59,CLTB,TALDO1,EEF1D,TIMM8B,DDX24,RPL8,RPS10,EDF1,SOX4,RPL27A,RPSA,EIF3K,HINT1,RPS14,NDUFA11,RPLP1,CLU,EHD4,FAU,RPS26 |
| 5.480e-04 | -7.51 | GSE17721_0.5H_VS_8H_POLYIC_BMDC_DN | MSigDB lists | GSE17721_0.5H_VS_8H_POLYIC_BMDC_DN | 194 | 47 | 17377 | 2626 |
PTMS,PDCD6IP,UBN1,MRPL39,HMGXB3,PPP1R15B,DLGAP4,PLAGL2,TM9SF3,CHIC2,MYNN,TBC1D13,PHC2,HOMER1,PCNA,EIF2S2,ATP6V0A2,MDFIC,MOB1A,MCMBP,FRMD8,GCC1,HTRA2,ARHGAP17,ETV3,LAP3,TMEM39A,MCL1,DIDO1,SEPT7,NEU1,ARF4,CLK3,CCDC6,TAB2,STK38,LUC7L3,OAZ2,ITGB1,ZNF436,TBPL1,PIAS2,RGL1,TAF12,MBD6,MAP3K5,RNF114 |
| 5.480e-04 | -7.51 | GSE9650_NAIVE_VS_MEMORY_CD8_TCELL_DN | MSigDB lists | GSE9650_NAIVE_VS_MEMORY_CD8_TCELL_DN | 194 | 47 | 17377 | 2626 |
TXN,FAM207A,PTTG1,MOGS,EPN1,HCFC1R1,STMN1,HLA-A,CAPN2,PCNA,SHC1,MBD2,BCL2,MDFIC,CLDND1,ST8SIA2,F2R,S100A6,LYPLA2,MAPRE2,POLR2L,KLF10,TNFAIP3,ELL2,TSPAN31,MAP7D1,PACS1,CYFIP2,KRTCAP2,VKORC1,ODC1,KLF6,XRCC5,MYO1F,NUCB1,SEPT1,AHNAK,RBMX,GADD45B,ITGB1,ATF6,HMGB2,PGAM1,CHPT1,ZMAT3,TOB1,PFKP |
| 5.510e-04 | -7.50 | LEI_MYB_TARGETS | MSigDB lists | LEI_MYB_TARGETS | 306 | 68 | 17377 | 2626 |
TMEM106C,TSC22D3,PTTG1,TPX2,SLC20A1,MAP1LC3B,PCBP1,STAM,KTN1,RBM4,DST,FARSA,PCNA,TARDBP,CDC25B,GM2A,ERCC1,MCL1,AURKB,DNAJA1,BICD2,MCM2,HSPA4,BRD2,STAT6,FASTK,E2F4,PDXK,CLU,LTA4H,TUBB,PPIB,SRSF6,SRGN,TRIO,CDK2AP2,FLOT1,CTCF,ASAH1,DNAJB1,RGS2,EBP,CFLAR,CD59,CLIC4,NDUFV1,NFATC3,NDUFS8,LPCAT1,ATP6V0D1,UBE2M,EEF1D,SLC25A1,LDHB,ELOVL5,TSTA3,PLEC,PTTG1IP,LY6E,COMMD4,GOSR1,ISG15,XRCC5,MAGED2,SETD3,GPI,UBE2C,PURA |
| 5.516e-04 | -7.50 | GO_DOUBLE_STRAND_BREAK_REPAIR | MSigDB lists | GO_DOUBLE_STRAND_BREAK_REPAIR | 148 | 38 | 17377 | 2626 |
RECQL,EYA1,BABAM1,CIB1,SMC6,BLM,MAD2L2,WDR48,RPA2,KDM2A,MTA1,XRCC2,MSH2,PRPF19,TDP1,ERCC1,RAD51AP1,PRKDC,BRCA1,DCLRE1C,GINS4,RAD54B,XRCC5,RPA1,RAD51C,PALB2,TONSL,NSMCE2,CDCA5,H2AFX,BAZ1B,XRCC3,CHEK2,YY1,XRCC4,GEN1,RAD51D,POLQ |
| 5.560e-04 | -7.49 | Epstein-Barr virus infection | KEGG pathways | ko05169 | 199 | 50 | 7161 | 1149 |
DDX58,USP7,NCOR2,POLR2K,HLA-E,CSNK2A1,IRF3,EIF2AK4,SND1,MAPK14,PRKACA,LYN,POLR3K,HLA-A,RB1,PSMD2,MDM2,PSMD1,CCNA2,PIK3R2,CDKN1B,BCL2,MAP3K14,ATF2,STAT3,POLR2I,POLR2L,POLR2G,TNFAIP3,AKT2,POLR2D,POLR3GL,EIF2AK1,POLR2A,HSPA1B,PSMC4,HLA-B,JAK1,POLR2J,TAB2,PSMD3,PSMD8,TBPL1,YWHAZ,RBPJ,CDK2,TRAF5,YWHAH,PSMC1,HDAC2 |
| 5.560e-04 | -7.49 | Epstein-Barr virus infection | KEGG pathways | hsa05169 | 199 | 50 | 7161 | 1149 |
DDX58,USP7,NCOR2,POLR2K,HLA-E,CSNK2A1,IRF3,EIF2AK4,SND1,MAPK14,PRKACA,LYN,POLR3K,HLA-A,RB1,PSMD2,MDM2,PSMD1,CCNA2,PIK3R2,CDKN1B,BCL2,MAP3K14,ATF2,STAT3,POLR2I,POLR2L,POLR2G,TNFAIP3,AKT2,POLR2D,POLR3GL,EIF2AK1,POLR2A,HSPA1B,PSMC4,HLA-B,JAK1,POLR2J,TAB2,PSMD3,PSMD8,TBPL1,YWHAZ,RBPJ,CDK2,TRAF5,YWHAH,PSMC1,HDAC2 |
| 5.567e-04 | -7.49 | N-acetyllactosamine synthase activity | molecular function | GO:0003945 | 4 | 4 | 17224 | 2647 |
B4GALT1,B4GALT4,B4GALT3,B4GALT2 |
| 5.575e-04 | -7.49 | DNA replication factor A complex | cellular component | GO:0005662 | 15 | 8 | 18223 | 2701 |
RPA2,TONSL,HELB,PURA,XPA,PRPF19,RPA1,CDC5L |
| 5.600e-04 | -7.49 | TPM1 (tropomyosin 1) | protein interactions | 7168 | 120 | 34 | 17029 | 2761 |
COX15,THOC1,KLHL21,TWNK,SF3B1,MYH9,COX4I1,PARK7,SRXN1,SF3B2,DLG5,HOMER1,ZNF746,CNN2,AHCYL1,ATF2,RBM15,CDC37,FOXK1,CAPZA2,BRCA1,VDAC1,ANLN,EPB41,GOLGA2,MYO18A,EXOC4,APPL2,COX5A,ACTB,PKD2,RBPJ,PPP6R3,CDK2 |
| 5.602e-04 | -7.49 | positive regulation of cellular protein localization | biological process | GO:1903829 | 310 | 69 | 17256 | 2622 |
RHOG,CYLD,DYNLL1,ANK3,PRKACA,SEC16A,MAPK14,BCAP31,PARK7,PRNP,MIEF1,CDK5,MDM2,GLIS2,PIK3R2,CNPY4,AP2B1,MAVS,TP53BP2,GPD1L,HTRA2,CHP1,PLK1,PLK3,CCT2,AKT2,KAT7,EZR,NUTF2,EDEM2,TRIM28,USP36,EPB41,ITGB1,STK11,TFDP2,MAPK1,OAZ1,NMD3,C2CD5,UBE2D3,TM9SF4,CDT1,PRKAA1,CIB1,NKD2,PSEN1,RAB11A,DDRGK1,KIF5B,PDCD10,HUWE1,GTSE1,ATG13,BCL2,PDPK1,TGFB1,ACSL3,CCT8,SH3GLB1,PCM1,OAZ2,TFDP1,PPP3R1,E2F1,NUP62,YWHAZ,RUFY3,YWHAH |
| 5.607e-04 | -7.49 | GSE19401_UNSTIM_VS_RETINOIC_ACID_AND_PAM2CSK4_STIM_FOLLICULAR_DC_UP | MSigDB lists | GSE19401_UNSTIM_VS_RETINOIC_ACID_AND_PAM2CSK4_STIM_FOLLICULAR_DC_UP | 189 | 46 | 17377 | 2626 |
MIF,SEPHS2,TMEM184B,SCAMP3,DHPS,MANBA,TRIO,GGA2,ABHD14A,BCAP31,MFSD10,PIP5K1C,WWP2,GNS,CDK5,RPN1,XPA,MSH2,TECR,ATP6V0D1,PHKG2,CARM1,TERF2,DCTN1,ERCC1,DEAF1,POLR2I,TIMP2,PBXIP1,HEBP2,EMP3,EZR,NDUFA7,PSMB9,ZFAND5,PI4K2A,SDHB,DDOST,PPP3R1,ASNA1,CLN3,PLOD3,ARRB2,YWHAH,HEXA,LTA4H |
| 5.607e-04 | -7.49 | GSE27786_CD8_TCELL_VS_NKCELL_UP | MSigDB lists | GSE27786_CD8_TCELL_VS_NKCELL_UP | 189 | 46 | 17377 | 2626 |
MIF,USP7,RRP15,KRBA1,NKD2,IP6K2,SNN,C19orf48,SLC20A1,SDHA,PARK7,FASTKD3,PDXP,ZKSCAN1,MECR,MSH2,TTC3,TOP1MT,TTLL12,F2R,RPL22L1,PPP6R1,KCNAB2,CYTH1,TIMP2,SEC61B,NSUN2,TBRG4,SREK1,DNAJC9,BCLAF1,UTP3,MEN1,NDRG3,EIF3G,BOLA3,NAP1L1,PDCD6,NIP7,VPS26B,CHD3,PRPS2,ACAT1,AEN,MBOAT1,DVL1 |
| 5.607e-04 | -7.49 | GSE2770_UNTREATED_VS_IL12_TREATED_ACT_CD4_TCELL_48H_UP | MSigDB lists | GSE2770_UNTREATED_VS_IL12_TREATED_ACT_CD4_TCELL_48H_UP | 189 | 46 | 17377 | 2626 |
UBE2D3,BCL2L12,RHOG,TSC22D3,WDR13,CAST,KLF13,MYO9B,INO80E,HMG20A,ATPAF1,PAIP2,STARD9,NFATC3,RAP1A,PRC1,SUCLG2,CDKN1B,GLE1,CNPY3,NCOA2,MND1,ERMP1,TACC1,PSPC1,DENND4C,PRKDC,OXR1,KIAA0930,CUL3,PLEKHM3,AZI2,CBFA2T2,MAPK3,HAUS8,MBIP,AGPAT2,ST3GAL2,ZFP90,NCOA1,PDXK,SMAD1,MAPK1,SSRP1,S100PBP,TMEM131 |
| 5.607e-04 | -7.49 | GSE31082_DN_VS_DP_THYMOCYTE_DN | MSigDB lists | GSE31082_DN_VS_DP_THYMOCYTE_DN | 189 | 46 | 17377 | 2626 |
OTUD5,TCF12,SLC30A9,KIF3B,ANKRD13D,DNAJC5,SF3B1,VAV2,CCM2,TM9SF3,AGPAT3,IP6K2,GGPS1,RLF,MAP1LC3B,CHD1,KIF5B,APLP2,INPP5A,FAM89B,AXIN2,TNPO2,AFF1,N4BP2,CTDSP2,PHKG2,CFL1,SMC4,ABCC5,SNX25,KDM3B,ORAI2,TNFAIP3,ATG9A,PPP1R21,LDB1,ZMYM5,ARHGDIB,DCLRE1C,PTTG1IP,PLEKHF2,USP32,RNF38,ACADM,BRWD3,TOB1 |
| 5.607e-04 | -7.49 | GSE5542_UNTREATED_VS_IFNA_TREATED_EPITHELIAL_CELLS_24H_UP | MSigDB lists | GSE5542_UNTREATED_VS_IFNA_TREATED_EPITHELIAL_CELLS_24H_UP | 189 | 46 | 17377 | 2626 |
ANKRD27,NF1,MYH9,MXD4,NCKAP1,REEP5,GIT2,CFLAR,MAN1A1,CAPN2,MBD2,ADCY9,LPIN2,PHTF1,PPP4R1,ZNF335,ANXA5,JOSD1,OSTF1,RNF19A,RNF135,F2R,C12orf75,SYTL3,PPP3CA,SNRNP200,TNFAIP3,EMB,EZR,ATXN1,ARHGEF12,OGDH,CBFA2T2,HERPUD2,RHBDF2,MYO1F,FAS,PI4K2A,CACNB1,CDCA4,AHNAK,UEVLD,LIMK1,ZDHHC7,YWHAH,LRP8 |
| 5.607e-04 | -7.49 | GSE2405_HEAT_KILLED_LYSATE_VS_LIVE_A_PHAGOCYTOPHILUM_STIM_NEUTROPHIL_9H_DN | MSigDB lists | GSE2405_HEAT_KILLED_LYSATE_VS_LIVE_A_PHAGOCYTOPHILUM_STIM_NEUTROPHIL_9H_DN | 189 | 46 | 17377 | 2626 |
UBE2D3,PRKAB1,LIME1,SCAMP3,CASP6,PHF23,CXXC1,RAE1,UROD,KLF13,ARFIP2,UBE2Q1,MYNN,DNAJB1,PAIP2,FERMT3,KRI1,GTPBP3,GSTK1,GART,NOL11,RAB35,BDH1,SLC35B4,BTF3L4,PIK3IP1,POLR1B,N4BP2,USP42,RNPS1,ITM2A,FBXO9,ARHGDIB,ICAM2,ERC1,RPA1,GEMIN5,PLD3,ACYP1,VPS26B,PIAS2,PITPNA,ANP32E,CCDC125,LTA4H,ZC3HC1 |
| 5.607e-04 | -7.49 | GSE25123_CTRL_VS_IL4_AND_ROSIGLITAZONE_STIM_MACROPHAGE_UP | MSigDB lists | GSE25123_CTRL_VS_IL4_AND_ROSIGLITAZONE_STIM_MACROPHAGE_UP | 189 | 46 | 17377 | 2626 |
TMEM106C,ZBED3,TP53RK,DNMT3A,LYRM4,PNISR,AGRN,NF1,TSC22D3,DNAJB2,CDK13,B4GALT4,EIF1B,GFM2,CSDE1,IRF4,SH3BP1,SNX18,AP2B1,CTR9,ANXA5,COPS7B,PIK3IP1,ALDH18A1,FBL,PPP3CA,RHOA,PPP1R18,TSPYL4,SIGMAR1,WDR18,NARF,UTP15,ARHGDIB,IL12RB1,NDRG3,ERC1,PEX5,PLAA,DDOST,E2F4,MAPK6,NLRC5,CAB39,PSAP,ZNF146 |
| 5.607e-04 | -7.49 | GSE5589_UNSTIM_VS_180MIN_LPS_STIM_MACROPHAGE_UP | MSigDB lists | GSE5589_UNSTIM_VS_180MIN_LPS_STIM_MACROPHAGE_UP | 189 | 46 | 17377 | 2626 |
NAT9,SMAP1,SYS1,NF1,FAM53C,DAP,MAGED1,C16orf87,VPS45,VTI1A,AGPAT3,ZADH2,FOXO3,HAUS2,HEATR5B,GOLM1,ATIC,DDA1,FJX1,COPS7B,LPCAT1,NAA35,RNLS,SLC25A1,DCTN1,FYTTD1,CLCN3,C16orf72,LAP3,DENND4C,LDHA,ADSS,CHCHD3,TMEM184C,ZNF862,TSC1,BRWD1,DUSP3,LIMK1,SEL1L,NDUFS5,TRAF5,PDLIM5,RPS26,PDF,TMEM33 |
| 5.607e-04 | -7.49 | GSE23308_CTRL_VS_CORTICOSTERONE_TREATED_MACROPHAGE_MINERALCORTICOID_REC_KO_UP | MSigDB lists | GSE23308_CTRL_VS_CORTICOSTERONE_TREATED_MACROPHAGE_MINERALCORTICOID_REC_KO_UP | 189 | 46 | 17377 | 2626 |
CTDP1,DCAF15,IVNS1ABP,TCF3,CERK,AP3M2,EZH1,MYO9B,FOXO3,ANKRD28,FAM192A,TBC1D22A,UCHL5,TTC3,SLC35C2,LPCAT1,NUP85,PHKG2,CTDSP2,CAMK2G,DCTN1,ARHGAP17,CIC,DCAF8,PIP4K2C,HTATIP2,GLO1,TOPORS,MTX1,MCM2,FANCE,DHX57,NEU1,TFEB,RPA1,GNAS,STK38,DTD1,ST3GAL2,ACADM,CHEK2,SMAD4,POT1,PURA,SLC25A39,SNAPIN |
| 5.607e-04 | -7.49 | GSE17721_0.5H_VS_12H_PAM3CSK4_BMDC_UP | MSigDB lists | GSE17721_0.5H_VS_12H_PAM3CSK4_BMDC_UP | 189 | 46 | 17377 | 2626 |
SRM,MBD1,COX15,RECQL,DNAJC5,H2AFZ,TRIM11,SRSF6,ARID5A,FAM76A,KLF13,GTF3A,HAUS4,MYO9B,GLRX3,GTF2F1,FERMT3,DECR1,INTS7,BDH1,AXIN2,ALDH18A1,TALDO1,S100A6,CDC37,NOL12,PSRC1,AGGF1,PTPN18,TIMP2,EID1,HELB,HNRNPF,KLF6,RFC2,TXNDC16,LIMK1,AEN,PRMT7,ZDHHC7,EHD4,PDLIM5,IGBP1,TOB1,ACSF2,RAB3IL1 |
| 5.607e-04 | -7.49 | GSE19923_WT_VS_HEB_KO_DP_THYMOCYTE_DN | MSigDB lists | GSE19923_WT_VS_HEB_KO_DP_THYMOCYTE_DN | 189 | 46 | 17377 | 2626 |
GALK1,CMAS,ABCB10,DNAJB1,GLRX3,PCBP1,PNO1,GOLM1,FARSA,GSTK1,RAB8A,NDUFV1,EXOSC7,TBC1D14,PARL,ATP6V0A2,SUCLG2,OSTF1,CREB1,METTL9,FRMD8,EEF1D,SHOC2,NTPCR,DRAP1,DENND4C,SMU1,E2F3,RRM2,KRAS,GLO1,TMEM147,EIF2A,TANC1,CLNS1A,ARF4,XRCC5,CDCA4,DDOST,PRDX3,PGRMC1,RWDD4,QRSL1,SPRYD4,HEXA,PGAM1 |
| 5.611e-04 | -7.49 | preribosome | cellular component | GO:0030684 | 77 | 23 | 18223 | 2701 |
PPAN,RRP15,EBNA1BP2,BMS1,UTP3,MAK16,RRP36,RPSA,KRR1,KRI1,UTP20,UTP25,NSA2,CMSS1,UTP18,NIP7,TBL3,NOC2L,RRS1,FBL,PDCD11,FTSJ3,BYSL |
| 5.611e-04 | -7.49 | Mitochondrial complex II deficiency | SMPDB pathways | SMP00548 | 20 | 10 | 992 | 167 |
SDHB,SUCLG1,IDH3A,MDH2,CS,SUCLG2,OGDH,IDH3B,SDHA,MPC1 |
| 5.611e-04 | -7.49 | Congenital lactic acidosis | SMPDB pathways | SMP00546 | 20 | 10 | 992 | 167 |
SDHB,SUCLG1,IDH3A,MDH2,CS,SUCLG2,OGDH,IDH3B,SDHA,MPC1 |
| 5.611e-04 | -7.49 | 2-ketoglutarate dehydrogenase complex deficiency | SMPDB pathways | SMP00549 | 20 | 10 | 992 | 167 |
SDHB,SUCLG1,IDH3A,MDH2,CS,SUCLG2,OGDH,IDH3B,SDHA,MPC1 |
| 5.611e-04 | -7.49 | Fumarase deficiency | SMPDB pathways | SMP00547 | 20 | 10 | 992 | 167 |
SDHB,SUCLG1,IDH3A,MDH2,CS,SUCLG2,OGDH,IDH3B,SDHA,MPC1 |
| 5.611e-04 | -7.49 | Pyruvate dehydrogenase deficiency (E2) | SMPDB pathways | SMP00551 | 20 | 10 | 992 | 167 |
SDHB,SUCLG1,IDH3A,MDH2,CS,SUCLG2,OGDH,IDH3B,SDHA,MPC1 |
| 5.611e-04 | -7.49 | Citric Acid Cycle | SMPDB pathways | SMP00057 | 20 | 10 | 992 | 167 |
SDHB,SUCLG1,IDH3A,MDH2,CS,SUCLG2,OGDH,IDH3B,SDHA,MPC1 |
| 5.611e-04 | -7.49 | Pyruvate dehydrogenase deficiency (E3) | SMPDB pathways | SMP00550 | 20 | 10 | 992 | 167 |
SDHB,SUCLG1,IDH3A,MDH2,CS,SUCLG2,OGDH,IDH3B,SDHA,MPC1 |
| 5.633e-04 | -7.48 | GMFB (glia maturation factor beta) | protein interactions | 2764 | 14 | 8 | 17029 | 2761 |
CSNK2A1,TARDBP,PRKACA,MAPK1,MAPK14,RPS6KA1,SETD3,MAPK3 |
| 5.633e-04 | -7.48 | RIT2 (Ras like without CAAX 2) | protein interactions | 6014 | 14 | 8 | 17029 | 2761 |
AFDN,LZTR1,RIT1,RGL1,RLF,APP,HRAS,SRPK2 |
| 5.633e-04 | -7.48 | GPT2 (glutamic--pyruvic transaminase 2) | protein interactions | 84706 | 14 | 8 | 17029 | 2761 |
BABAM1,CUL3,ADSL,USP20,AHCY,GPD1L,APP,CFL1 |
| 5.633e-04 | -7.48 | GREB1 (growth regulating estrogen receptor binding 1) | protein interactions | 9687 | 14 | 8 | 17029 | 2761 |
TGFB1,CDKN2C,XRCC3,PALB2,RB1CC1,SMAD4,HRAS,TKT |
| 5.641e-04 | -7.48 | proton-transporting two-sector ATPase complex | cellular component | GO:0016469 | 50 | 17 | 18223 | 2701 |
PPIF,ATP5IF1,ATP6V0A1,ATP5F1B,ATP5MF,ATP6V1B2,ATP5PF,ATP6V0B,ATP6V1D,ATP5MC3,ATP6V0A2,ATP6V0C,ATP5F1A,ATP6V1C1,ATP6V0D1,ATP6V0E1,ATP6V1G1 |
| 5.673e-04 | -7.47 | MBD3 (methyl-CpG binding domain protein 3) | protein interactions | 53615 | 84 | 26 | 17029 | 2761 |
PHF20L1,EWSR1,MTA2,SMARCA4,NFATC2,TCF19,MBD3,PARK7,KPNA1,GOLGA2,CHD3,TAB2,MTA1,MBD2,UHRF2,BAZ1B,DDX5,FUS,RBBP4,TAF6,IGBP1,DNMT1,ZNF800,HDAC2,DDB1,HNRNPM |
| 5.673e-04 | -7.47 | BUB3 (BUB3, mitotic checkpoint protein) | protein interactions | 9184 | 84 | 26 | 17029 | 2761 |
CPNE1,ZNF207,USP7,EXOC3,CCT2,CUL3,RNPS1,KCTD20,BRCA1,CDC23,MCM2,SF3A2,CCT8,RPA1,RPA2,SMAD2,CDC27,INTS7,HUWE1,DNM2,YBX1,BTBD10,USP11,ANAPC4,HDAC2,CDC5L |
| 5.679e-04 | -7.47 | MRPL37 (mitochondrial ribosomal protein L37) | protein interactions | 51253 | 71 | 23 | 17029 | 2761 |
TK1,MRPL9,CYLD,MRPL42,MRPL39,TCF3,MRPL12,CUL3,MRPL16,PM20D2,STOML2,MRPL50,MRPL2,PDCD6,MRPL55,MRPL27,MRPL40,CYC1,MRPL11,MRPL13,MRPL3,MRPL32,HNRNPM |
| 5.679e-04 | -7.47 | FOXO3 (forkhead box O3) | protein interactions | 2309 | 71 | 23 | 17029 | 2761 |
PLK1,USP7,FOXK1,CDT1,BRCA1,ERBIN,RB1,MDM2,PCNA,SMAD2,CDC27,RBL1,MAPK6,H2AFX,ARHGEF2,CDKN1B,YWHAZ,TAF5L,SMAD1,YWHAH,NIPSNAP2,MAPK1,SMAD4 |
| 5.679e-04 | -7.47 | POLR2F (RNA polymerase II subunit F) | protein interactions | 5435 | 71 | 23 | 17029 | 2761 |
CTDP1,POLR2I,POLR2G,POLR2K,ELOA,SDC2,POLR3GL,PSMB9,KDM3A,APP,POLR3K,POLR2A,GTF2F1,MAP3K4,KEAP1,MED10,POLR2J,CD3EAP,MED15,CRCP,POLR1B,ZNRD1,RPRD1B |
| 5.679e-04 | -7.47 | HAP1 (huntingtin associated protein 1) | protein interactions | 9001 | 71 | 23 | 17029 | 2761 |
IMMT,TOMM20,ATXN3,KAT7,GADD45G,RPS10,UTP3,ATP5MF,PDCD7,CDC73,PABPC4,HGS,PCM1,HSPA4,TIMM17A,SRSF4,KBTBD7,BRD7,NDUFB9,KPNA2,LUC7L2,SNAPIN,DCTN1 |
| 5.684e-04 | -7.47 | TUBA1A (tubulin alpha 1a) | protein interactions | 7846 | 261 | 63 | 17029 | 2761 |
UBE2D3,PDCD6IP,MAX,MAPRE1,CYLD,ATXN3,PHB2,PRKCSH,PRKAA1,B4GALT1,CDK13,ATP5F1B,BLM,ATP6V1B2,RUFY1,TUBGCP2,CDC73,GLMP,RPL11,MAT2B,KIF5B,VAV1,RB1,PSMD1,SHC1,PTEN,SIAH1,SOCS6,HTRA2,MLST8,PLK1,STAU1,TK1,NCK1,VHL,CUL3,NFATC2,AURKB,IL12RB1,MCM2,DDX39A,MAT2A,SOCS7,MAGED2,TIMM17A,MAPK6,ITGB1,USP32,CBWD1,STK11,XRCC3,YWHAZ,FKBP5,FUS,CHEK2,ARRB2,CD81,ECPAS,SMURF1,CDKN2A,TUBB,NUDT3,GEMIN7 |
| 5.707e-04 | -7.47 | CACCAGC,MIR-138 | MSigDB lists | CACCAGC,MIR-138 | 210 | 50 | 17377 | 2626 |
RMND5A,ANXA6,RHOC,RPS6KA1,UBE2Q1,CHKB,MXD4,ARF1,DCUN1D4,SLC20A1,ZNF518A,MYEF2,MEAF6,ZER1,PTPN2,RIMS3,JAZF1,PTPN11,DCP1A,SEPT11,JOSD1,TIPARP,SENP1,DVL2,SEH1L,ELOF1,EID1,ZMYND11,KIAA0930,USP10,UBE2V1,MIER2,CBFA2T2,SOX4,MACF1,ERC1,CLNS1A,SMAP2,DHX57,SUGP1,L3MBTL3,CLK3,LIMK1,ZC3H7B,BAZ1B,NCOA1,H3F3A,ZMIZ1,SMURF1,PRPF4B |
| 5.721e-04 | -7.47 | UBB (ubiquitin B) | protein interactions | 7314 | 231 | 57 | 17029 | 2761 |
WSB2,USP7,ATXN3,DNAJB2,SUZ12,TRIM11,CDT1,CUTA,XIAP,DLGAP4,ENSA,BRAP,USP48,DAZAP2,LYN,COMMD8,FAM8A1,HAUS2,APP,TUBGCP2,CDC73,HLA-A,RAD23A,MDM2,PCNA,ARPC5,HUWE1,MCM5,PIN1,RAD23B,CDKN1B,COPS7B,ATP6V0D1,CSNK1G3,TRAPPC13,TNFAIP3,BIRC3,EID1,AKT2,MYBL2,AURKB,BRCA1,ADRB2,MCM2,PRMT2,RHEB,DHX57,MAGED2,HGS,PFDN4,MED15,YWHAZ,ARRB2,SMURF1,AP2S1,APOL2,SMAD4 |
| 5.729e-04 | -7.46 | meninges-meningioma-fibroblastic | COSMIC cancer mutations | meninges-meningioma-fibroblastic | 15 | 8 | 17385 | 2587 |
CDKN2C,KRAS,NRAS,NF1,PTEN,HRAS,SMAD4,CDKN2A |
| 5.729e-04 | -7.46 | GH | COSMIC cancer mutations | GH | 15 | 8 | 17385 | 2587 |
GNAS,CDKN2C,RB1,NRAS,KRAS,MEN1,HRAS,CDKN2A |
| 5.729e-04 | -7.46 | autonomic_ganglia-head_neck-paraganglioma | COSMIC cancer mutations | autonomic_ganglia-head_neck-paraganglioma | 15 | 8 | 17385 | 2587 |
GNAS,KRAS,MAX,NRAS,MEN1,VHL,HRAS,CDKN2A |
| 5.729e-04 | -7.46 | pituitary-adenoma-GH | COSMIC cancer mutations | pituitary-adenoma-GH | 15 | 8 | 17385 | 2587 |
GNAS,CDKN2C,RB1,NRAS,KRAS,MEN1,HRAS,CDKN2A |
| 5.730e-04 | -7.46 | GSE2770_TGFB_AND_IL4_VS_IL12_TREATED_ACT_CD4_TCELL_48H_DN | MSigDB lists | GSE2770_TGFB_AND_IL4_VS_IL12_TREATED_ACT_CD4_TCELL_48H_DN | 184 | 45 | 17377 | 2626 |
SLC12A7,RMND5A,RHOG,DNMT3A,FAM208B,JMJD6,EPHX2,YY1AP1,DNAJB9,CREM,RAB21,SYNM,MEX3C,UTP18,DPYSL2,RABGAP1L,AKAP8,MRPL54,CDC25B,NAP1L4,C12orf75,MCMBP,CDK12,KCNAB2,BAK1,PPIF,ARHGAP17,BTG2,TEX10,AMD1,FRAT2,DNAJC9,DDX39A,PICALM,EIF3A,AKAP1,MTHFD2,KIF18A,BIRC5,FAM110A,TICAM1,SRSF3,PLOD3,TUBB,LRCH1 |
| 5.730e-04 | -7.46 | GSE11924_TFH_VS_TH2_CD4_TCELL_UP | MSigDB lists | GSE11924_TFH_VS_TH2_CD4_TCELL_UP | 184 | 45 | 17377 | 2626 |
TRIM41,AGPAT1,MYH9,EZH1,PDCD7,PDXDC1,CNOT3,PIP5K1C,FBRS,HOMER1,KLHL20,HDAC7,PPIG,PPME1,EI24,AKR1B1,UPF2,MAP3K14,ABI1,ZC3H3,ARID4A,HP1BP3,ADCY7,PHF20L1,EID1,PPP1R21,RPS10,LNX2,WDR82,PACS1,PBRM1,MEF2D,NFATC2IP,HERPUD2,FAS,HLA-B,HGS,ARAP1,GLG1,ATE1,NCLN,ST3GAL2,TMEM101,CABLES1,PDCD4 |
| 5.730e-04 | -7.46 | GSE43955_TH0_VS_TGFB_IL6_TH17_ACT_CD4_TCELL_42H_UP | MSigDB lists | GSE43955_TH0_VS_TGFB_IL6_TH17_ACT_CD4_TCELL_42H_UP | 184 | 45 | 17377 | 2626 |
CYTIP,SART1,TOR3A,EIF3D,TAP1,NUP54,C5orf30,SMC6,RRAGC,GLUD1,SLC35B2,MAPK14,CSNK1A1,CAPN2,PHTF1,MRPL34,BRI3,ANKRD13C,TTC3,PTGES3,MOB1A,GM2A,TXNL1,DEAF1,TRAFD1,RBM42,SIGMAR1,LAP3,ZNF574,DIDO1,RAB5B,ISG15,PRDX1,ASF1B,HSPA1B,AHNAK,PPP2R5A,VPS26B,BCL7C,SLC25A19,ACADM,NDE1,TAF6,PURA,TSEN15 |
| 5.730e-04 | -7.46 | GSE16385_IL4_VS_ROSIGLITAZONE_STIM_MACROPHAGE_UP | MSigDB lists | GSE16385_IL4_VS_ROSIGLITAZONE_STIM_MACROPHAGE_UP | 184 | 45 | 17377 | 2626 |
PRPF38B,RPLP2,NACA,GTF3A,EDC3,PIP5K1C,FBXO3,INPP5A,TBC1D22A,MTA1,DUT,TTC3,TTC17,VPS13B,CARS2,PPP3CA,ERMP1,MLEC,POLR2G,PIGT,NUDT4,PRKDC,RDH10,SCFD2,RPL8,ILF3,KCTD20,ATXN1,BCLAF1,ESYT1,CDC23,MACF1,NMT2,TSC1,GALNT2,ATAD2,QARS,RPS14,RPLP1,IARS2,CENPT,SPCS3,ZMIZ1,B4GALT3,PDSS2 |
| 5.730e-04 | -7.46 | GSE8384_CTRL_VS_B_ABORTUS_4H_MAC_CELL_LINE_UP | MSigDB lists | GSE8384_CTRL_VS_B_ABORTUS_4H_MAC_CELL_LINE_UP | 184 | 45 | 17377 | 2626 |
CYTIP,PTMS,MIF4GD,GNPDA1,PTTG1,HAUS4,EZH1,CNTROB,FKBP2,AP1B1,RGS2,FOXO3,MBD4,CYHR1,SUB1,SH3BP1,PIK3R2,ADCY9,YBX1,ABCD1,RNF26,S100A6,MLST8,TK1,PTPN18,RNASEH2C,CIC,HELB,WDHD1,NUSAP1,ESYT1,PEF1,CHAF1A,CBX3,RPL37,ALG3,GOLGA7,PARG,ACOX1,TBL3,NCOA1,CHEK2,MYO9A,TERF1,PDCD4 |
| 5.730e-04 | -7.46 | GSE21546_SAP1A_KO_VS_SAP1A_KO_AND_ELK1_KO_ANTI_CD3_STIM_DP_THYMOCYTES_UP | MSigDB lists | GSE21546_SAP1A_KO_VS_SAP1A_KO_AND_ELK1_KO_ANTI_CD3_STIM_DP_THYMOCYTES_UP | 184 | 45 | 17377 | 2626 |
HSPH1,ABCA3,ADD1,NQO1,UBXN1,ABCB10,PXMP2,PPP3CB,BLM,SDHA,PABPC4,JMY,XPR1,LMNA,UBLCP1,DTL,APLP2,BDH1,ATP13A3,TPST1,MRPL54,RNF19A,MINPP1,SLC12A2,LUC7L2,PLK1,ZMYM5,CPOX,LDB1,NARF,PIP4K2C,SEPT8,UHRF1BP1,RAB22A,NECAP2,TSC1,PEX5,NEK1,BEND3,CHEK2,TFDP2,SLC22A23,E2F2,ARHGAP23,ZMAT3 |
| 5.730e-04 | -7.46 | GSE13411_SWITCHED_MEMORY_BCELL_VS_PLASMA_CELL_UP | MSigDB lists | GSE13411_SWITCHED_MEMORY_BCELL_VS_PLASMA_CELL_UP | 184 | 45 | 17377 | 2626 |
RHOG,PARP12,YTHDC2,AP3M2,USP39,CDK13,NKRF,MAP1LC3B,GGPS1,RAPGEF6,EXT2,CHD1,GIT2,APP,NPLOC4,SLC25A36,FAM192A,CTNNBL1,SP100,SIAH1,RNFT1,CORO1A,TP53BP2,MAML1,MORC3,PTPRK,MOB4,CSNK1G2,SEPT9,PGS1,PRPF3,DCLRE1C,METTL22,NDRG3,KDM3A,MTR,PLEKHF2,NECAP2,HHEX,OAZ2,MEGF9,NCOA1,MAPK1,ZMAT3,NUDT3 |
| 5.730e-04 | -7.46 | GSE17721_CTRL_VS_GARDIQUIMOD_12H_BMDC_UP | MSigDB lists | GSE17721_CTRL_VS_GARDIQUIMOD_12H_BMDC_UP | 184 | 45 | 17377 | 2626 |
MRPL42,CASP6,PIGQ,ANKH,GNE,CENPF,SNX15,MRPS26,GLUD1,LANCL1,HCFC1R1,PABPC4,XPR1,GOLM1,HOMER1,NDUFA2,RNFT1,DAD1,HADHB,ABCD1,CORO1A,CPSF4,TMEM14C,EEF1D,PDLIM2,EIF3L,ARHGAP17,PTPN18,RPL6,HTATIP2,ASF1B,SUPT16H,ANKRD10,MRPL2,MBIP,QRSL1,HMGB2,CTSA,STK11,NANP,CDK2,CD81,SNX14,SLC25A39,MYL12B |
| 5.730e-04 | -7.46 | GSE12845_IGD_NEG_BLOOD_VS_PRE_GC_TONSIL_BCELL_UP | MSigDB lists | GSE12845_IGD_NEG_BLOOD_VS_PRE_GC_TONSIL_BCELL_UP | 184 | 45 | 17377 | 2626 |
MAGEH1,CORO7,TMEM184B,SCAMP3,PPP1R2,GORASP1,DAP,UFC1,TMED3,RSAD1,EBP,DECR1,COQ4,IMPAD1,FAM89B,ACAD8,NDUFA3,SLC35A1,S100A6,DNAL4,PREB,NAGPA,HMGN4,EID1,PPIE,HTATIP2,EIF2AK1,GORASP2,METTL22,SERP1,RHOB,MYO1F,SEC31A,ALG3,CHCHD3,UAP1,TMED10,ITGB1,ACBD4,ATF6,STK11,CTSA,PIEZO1,ACSF2,ATP6V0E1 |
| 5.730e-04 | -7.46 | GSE27786_NEUTROPHIL_VS_MONO_MAC_DN | MSigDB lists | GSE27786_NEUTROPHIL_VS_MONO_MAC_DN | 184 | 45 | 17377 | 2626 |
RRP15,RPLP2,PRKCSH,POC1A,TRAK1,MOGS,LETMD1,FKBP2,GGA2,CHD1,POLR3K,SEC11A,NOL11,ZNF639,DNAAF2,ZNF326,SUCLG2,TRA2B,LDLRAD3,EEF1D,GINS1,SRP72,TSHZ1,RPL35,POLK,RAD51AP1,BMS1,CDC6,NUP155,BRCA1,FXR1,CCNF,AP4E1,EIF3A,PRIM1,DTWD1,MRPL2,BOLA3,WDR11,DUS3L,UAP1,QARS,WDR76,TIGD2,ZNF511 |
| 5.740e-04 | -7.46 | negative regulation of metabolic process | biological process | GO:0009892 | 2974 | 511 | 17256 | 2622 |
FGFR1OP,TXN,ZNF496,MAX,H2AFZ,TSC2,KDM4A,TSC22D3,XIAP,YTHDF3,CCNB1,UBE2I,PPP1R16B,RBM4,RIC1,PARK7,RPL23A,CALM2,CDK5,CDKN2C,PA2G4,CIPC,PARPBP,SRSF4,TRA2B,CRY2,FNIP2,SMARCE1,TIPARP,DNMT1,SENP1,SRSF10,BAK1,PLK3,ERCC1,KLF10,AATF,GABPA,PBK,EHMT1,DDX20,MCL1,AURKB,EIF3A,PLEKHF2,DOT1L,BRMS1,HHEX,SMAD2,RPS27A,RPS14,LIMK1,AXIN1,PRDX5,OGT,SMG9,TFDP2,SMAD1,ARRB2,HDAC2,PDCD4,SVIP,HSPH1,GMFG,PHF23,GSPT2,PRKAA1,DHX9,EIF2AK4,NOTCH2,PARN,PSEN1,METTL3,VPS25,CDC73,CNOT3,CFLAR,DDRGK1,TFAP4,CD59,FKBP1A,SMC3,EXOSC7,MEX3C,KLF16,HDAC7,FBXO7,PHF14,MSH2,DAPK1,PIK3IP1,MVP,GNAI2,LPCAT1,TNRC18,PABPC1,TERF2,SOCS5,RBM42,ETV3,FOXK1,ZMYND11,MTA2,GTPBP4,RPS10,ITM2A,RPS24,BCLAF1,EXOSC9,ARID1A,CBFA2T2,FXR1,KDM3A,PATL1,MAP2K2,PHF6,XRCC5,EPRS,PFDN5,GOLGA2,ETS2,DUSP3,CSK,RBMX,QARS,CABIN1,CNOT6,YY1,ZNF830,CDK2,RNF139,CDKN2A,EGLN1,ZNF296,PPP1R37,DNMT3A,GGNBP2,RPS6KA1,UBR2,SUZ12,CAST,RAF1,PTTG1,MAGED1,WDTC1,RCOR3,APP,PAIP2,TERF2IP,SPINDOC,APLP2,SHC1,SP100,MTA1,TBC1D14,UCHL5,SOCS6,CDKN1B,RBM15,ATF2,GPD1L,CGGBP1,PDCL3,RNF169,SAP30,ANKLE2,CPNE1,EID1,ERF,DRAP1,RPL38,POLR2D,RNPS1,CUL3,CIRBP,PKMYT1,DNAJA1,H2AFV,TRIM28,DDX17,SOCS7,PPP2CA,CHCHD3,ZNF282,CHMP4A,PPP2R5A,DGCR8,LSM6,CORO1C,HIPK2,NT5C3B,H2AFX,RPLP1,STAT1,BEND3,PPP5C,LRP8,POLQ,POU3F2,NCOR2,RPS2,DEPDC1,SRSF6,MECP2,TCF3,SECISBP2,AKT1S1,BLM,HMG20A,FOXO3,MAD2L2,TUT4,WWP2,PDCD10,ITGB8,SUV39H2,RPL17,PTEN,PPP1R8,AXIN2,DCP1A,RPL19,UPF2,CITED2,CNOT6L,CREB1,NCOA2,MSH6,TSHZ1,PDPK1,PPP3CA,TNFAIP3,RPL8,ILF3,KCNQ1,ZP3,PDE3B,RPL27A,PICALM,CBX3,SH3BP5,RPL32,GPS2,ZHX1,PRDX3,PITX1,LRPPRC,PML,KHSRP,PPP1R11,DDX5,HMGB2,PARP10,IGBP1,CPEB2,PURA,RORB,ZBED3,THOC1,NF1,TRIM11,PPP1R15B,FAM129A,RBM8A,ENSA,CSNK2A1,SND1,SIRT2,UBQLN2,MAPK14,BECN1,BIRC2,EDC3,CREM,PRNP,CYREN,RAP1A,EIF4A3,GLIS2,ZNF639,METTL14,JAZF1,ETV6,PIK3R2,NOC2L,PPP1R12C,SLC35C2,OGG1,ARID4A,CCAR1,RYBP,PTPRK,PLK1,SP3,DEAF1,LARS,EXOSC6,PBXIP1,NCK1,BAZ2A,VHL,RIOX2,GMFB,EZR,CDC6,LRP5,BRCA1,SOX4,PRKRA,OPTN,RPL37,PAF1,EIF4ENIF1,TONSL,SOCS4,ZNF268,STK11,CHEK2,CLU,DVL1,ROCK1,CLN3,BEND6,RPS26,POT1,ZNF564,UBE2D3,RPS15,ZCCHC9,PPP1R2,PPP1R12A,PHB2,CENPF,UBXN1,CIB1,CTCF,TIA1,RPL15,MEF2A,DNAJB1,THRAP3,RGS2,CNOT11,TTF1,SRRT,PRPF18,LYAR,RB1,MLX,NFATC3,TIGAR,MBD2,ZNF746,ARL6IP1,CTR9,TIMELESS,BCL2,MDFIC,YBX1,MCPH1,ZNF189,CREG1,ERLIN1,CIC,OXR1,LDB1,RPL6,GBA,EIF2AK1,RTF1,EIF4G2,DAPK3,ISG15,ZNF174,MASTL,RPL36,TSC1,MBIP,SYNCRIP,ORMDL2,KLHL15,NFIL3,SIAH2,NUP62,CTSA,ZFP90,RUVBL2,RBBP4,SNRNP70,TOB1,N4BP2L2,USP7,MBD1,ASH1L,FEZ2,RPLP2,MPHOSPH8,FOXM1,DYNLL1,SMARCA4,IRF3,LYN,DUSP22,PAIP1,MXD1,RPL11,HNRNPA2B1,SAP130,CSDE1,ZBTB21,MDM2,TNFAIP8,PIN1,PPME1,EXOSC1,TARDBP,STRAP,CTDSP2,HTRA2,RLIM,MOSPD1,CHP1,SNX25,PPIF,UBQLN4,RPL29,TIMP2,RPL35,BIRC3,POLR2G,FAM172A,ZNF500,PGGT1B,BTG2,PCGF6,ATXN1,NFATC2,MBD3,RPS9,USP36,RPSA,DNAJC10,IDE,ATP1A1,TAB2,RBL1,HNRNPR,SCAP,MAFK,STAT6,STK38,GADD45B,ARNTL,DNAJC17,CHMP4B,H3F3A,SMAD4,CBX4,PARD3,BCL2L12,MIF,DNAJC2,UNK,TRIP12,DAP,AGO2,ARID5A,PAWR,NKRF,MXD4,FBXO5,PTPN2,KMT5A,PELO,DUS2,H2AFY,BRD7,STAT3,RNF5,RBM15B,TGFB1,SAMD4B,PPP1R9B,RHOA,BTAF1,PSPC1,ZNF202,PRKDC,HELB,PRKAR1B,RFFL,RCOR1,WDR81,MEN1,PRMT2,HSPA1B,CNOT9,LEMD2,UPF1,PLAA,BIRC5,ZC3H7B,E2F1,GLG1,KMT2B,RBPJ,NR2F2,HRAS,HIPK3,TERF1,IFI16 |
| 5.743e-04 | -7.46 | GO_CELLULAR_RESPONSE_TO_NITROGEN_COMPOUND | MSigDB lists | GO_CELLULAR_RESPONSE_TO_NITROGEN_COMPOUND | 479 | 99 | 17377 | 2626 |
MAX,DNMT3A,AGRN,UBR2,WDTC1,RRAGC,IRF3,SIRT2,BCL2L1,ATP6V1B2,PRKACA,LYN,GNB2,APP,EEF2K,HNRNPA2B1,USF1,PDK2,ATP6V0B,RAB8A,RAP1A,MDM2,CCNA2,SHC1,RALB,PIK3R2,ADCY9,DNM2,AKR1B1,MAVS,AHCYL1,DNMT1,ADCY7,ATP6V1G1,CDC5L,KLF10,AKT2,GNG7,SLC26A6,EZR,ATP6V0A1,CDC6,BRCA1,PRKRA,SOCS7,IDE,SMAD2,DGCR8,STAT6,OGT,ATP6V0C,SMAD1,MAPK1,ATP6V0E1,HDAC2,SLC25A33,AGTRAP,PRKAA1,FLOT1,LAMTOR3,BLM,AP3S1,METTL3,SRRT,PTPN2,CAPN2,PDXP,ANXA5,ARHGEF2,ATP6V0A2,CREB1,GNAI2,STAT3,ATP6V0D1,MYO5A,PDPK1,PPP1R9B,DENND4C,PRKDC,PRKAR1B,RANGAP1,SRSF5,KCNQ1,MEN1,PDE3B,KLF6,MTR,APPL1,MAPK3,FAS,AKAP1,GNAS,ATP6V1D,CSK,MAP3K5,ATP6V1C1,CDK2,CPEB2,ZC3HAV1 |
| 5.758e-04 | -7.46 | positive regulation of proteolysis | biological process | GO:0045862 | 354 | 77 | 17256 | 2622 |
KARS,ATXN3,IFI27L1,SUMO2,MYH9,SIRT2,UBQLN2,LYN,MAPK14,BCAP31,ANKIB1,APP,FBXO22,USP5,RAD23A,MDM2,PDCD2,RNF19A,F2R,CLN6,SENP1,HTRA2,PLK1,BAK1,PLK3,RBX1,EDEM2,TIMM17A,AXIN1,SOCS4,PLGRKT,OGT,ADAM9,TRIM32,CLU,DVL1,SMURF1,PSMC1,HDAC2,CSNK1D,USP13,DAP,NKD2,CYCS,CSNK1A1,PSEN1,RHBDD1,APOPT1,WDR48,DDRGK1,CFLAR,TFAP4,PTEN,TANK,DAPK1,STAT3,SOCS5,ATP5IF1,RHOA,LONRF3,GBA,CYFIP2,PICALM,FADD,FAS,PSMC4,HSPA1B,MAPK3,HSPBP1,PDCD6,KEAP1,PML,MAP3K5,RNF14,RNF139,IFI16,RNF114 |
| 5.786e-04 | -7.45 | regulation of metaphase/anaphase transition of cell cycle | biological process | GO:1902099 | 49 | 17 | 17256 | 2622 |
PLK1,ZNF207,CDT1,CENPF,CUL3,CDC6,CCNB1,CDC23,MAD2L2,RB1,NEK6,NSMCE2,XRCC3,GEN1,UBE2C,ESPL1,ANAPC4 |
| 5.788e-04 | -7.45 | regulation of mitochondrion organization | biological process | GO:0010821 | 178 | 44 | 17256 | 2622 |
UBE2D3,TSC2,DYNLL1,PRKAA1,BCL2L1,PARK7,APOPT1,LMNA,MIEF1,MOAP1,TIGAR,HUWE1,FBXO7,PARL,BCL2,ATG13,TP53BP2,LMAN1,HTRA2,CDC37,PPIF,BAK1,ATP5IF1,GBA,VDAC1,RHOT1,SLC25A5,RHOT2,USP36,SH3GLB1,OPTN,MFN2,STOML2,INF2,TFDP1,PPP3R1,E2F1,YWHAZ,CLU,TFDP2,SMURF1,TMEM14A,YWHAH,ARRB2 |
| 5.789e-04 | -7.45 | purine nucleoside binding | molecular function | GO:0001883 | 372 | 81 | 17224 | 2647 |
RHOG,RAB14,RAB11B,RAC1,OLA1,TPX2,RRAGC,GLUD1,EFL1,MIEF1,RAB21,RAB8A,RAP1A,CDC42,SAR1A,RALB,RAB35,RAB4A,DNM2,UPRT,SEPT11,SUCLG2,RP2,EIF5,ARL5A,RHOBTB3,NRAS,SEPT9,CGAS,RAB7A,RAB1A,ARL5B,RAB5B,RAB22A,LSG1,RAB2B,ARF4,RHEB,DAP3,SEPT1,RAB24,GUCY1B1,TUBB,RHEBL1,ANXA6,RHOC,GSPT2,RAB23,ARFIP2,RAB6A,ARF1,IFT27,RAB11A,GFM2,RTKN,GTPBP3,ARF5,EFTUD2,DAPK1,GNAI2,RHOA,NOA1,TUFM,GTPBP4,SEPT8,BMS1,KRAS,RIT1,RHOT1,SEPT7,RHOT2,GUF1,RHOB,MFN2,GNAS,ADSS,GNA12,RAB18,PRPS2,EHD4,HRAS |
| 5.791e-04 | -7.45 | GO_POSITIVE_REGULATION_OF_MRNA_PROCESSING | MSigDB lists | GO_POSITIVE_REGULATION_OF_MRNA_PROCESSING | 29 | 12 | 17377 | 2626 |
PAF1,POLR2G,BTG2,RBMX,TRA2B,THRAP3,SNRNP70,CCNB1,CDC73,PABPC1,TOB1,PRPF19 |
| 5.791e-04 | -7.45 | NUNODA_RESPONSE_TO_DASATINIB_IMATINIB_UP | MSigDB lists | NUNODA_RESPONSE_TO_DASATINIB_IMATINIB_UP | 29 | 12 | 17377 | 2626 |
CCNA2,CASP6,E2F4,GADD45B,E2F3,BCL2,CDK13,XRCC3,MCL1,CDC25B,XRCC4,STAT3 |
| 5.791e-04 | -7.45 | GO_RNA_STABILIZATION | MSigDB lists | GO_RNA_STABILIZATION | 29 | 12 | 17377 | 2626 |
SYNCRIP,E2F1,CIRBP,DHX9,AXIN2,YBX1,TARDBP,THRAP3,MAPK14,PABPC1,PAIP1,RBM38 |
| 5.791e-04 | -7.45 | GUTIERREZ_MULTIPLE_MYELOMA_UP | MSigDB lists | GUTIERREZ_MULTIPLE_MYELOMA_UP | 29 | 12 | 17377 | 2626 |
CSDE1,SRP72,EID1,VDAC2,SUCLG2,DCTD,YWHAZ,ARF1,VDAC1,ATP6V0E1,RHOB,RHEB |
| 5.792e-04 | -7.45 | TATTATA,MIR-374 | MSigDB lists | TATTATA,MIR-374 | 274 | 62 | 17377 | 2626 |
RORB,TCF12,ADAM10,ARID2,PHRF1,EYA1,MECP2,YTHDF3,GNB2,TMEM161B,ZER1,LIN9,TFAP4,FKBP1A,HOMER1,MLX,EIF2S2,MEX3C,ETV6,AFF1,PIKFYVE,ST8SIA2,HDHD2,PPP6R1,SRPK2,PDPK1,MOB4,SP3,DCAF6,C16orf72,GOPC,MBLAC2,AMD1,ATXN1,MAP4K3,MTMR12,MEF2D,CAPZA2,BICD2,SOX4,ANLN,EIF4G2,BSDC1,EIF3A,CAND1,VEZF1,BOLA3,SERTAD2,HSPA4,ATP1A1,WDR11,WNT5B,ZC3H7B,MAPK6,SOCS4,RNF38,NCOA1,NR2F2,PURA,CBX4,ATMIN,NUMB |
| 5.798e-04 | -7.45 | Taok2 (TAO kinase 2) | protein interactions | 381921 | 6 | 5 | 17029 | 2761 |
CHMP4B,CLU,UPF1,PPP1R18,RCOR3 |
| 5.798e-04 | -7.45 | RASGRP2 (RAS guanyl releasing protein 2) | protein interactions | 10235 | 6 | 5 | 17029 | 2761 |
KRAS,RAP1A,NRAS,FAM118B,APP |
| 5.809e-04 | -7.45 | lysosomal membrane | cellular component | GO:0005765 | 357 | 76 | 18223 | 2701 |
RAB14,ABCC10,AP1B1,ATP6V1B2,GNB2,CMTM6,CPNE3,GLMP,NAPG,AP1M1,CLCN6,BRI3,AP2B1,MARCH2,TMEM9,TMBIM1,SEH1L,DRAM2,ATP6V1G1,WDR41,CPNE1,MIOS,GOPC,RAB7A,ATP6V0A1,SLC17A5,RHEB,AHNAK,WDR11,SURF4,DDOST,WDR59,AP1S1,ATP6V0C,SCARB1,CLN3,AP2S1,STARD3NL,DNAJC5,ANXA6,CCZ1,MANBA,CDIP1,FLOT1,LAMTOR3,B4GALT1,PSEN1,TMEM165,TMEM179B,SPPL2A,ZNRF2,ATP6V0A2,TMEM8A,LPCAT1,ATP6V0D1,TPCN1,MFSD12,ACP2,GBA,WDR81,SPPL2B,RMC1,NEU1,PI4K2A,SCARB2,ATP6V1D,MAGT1,NSF,CCZ1B,SNAP29,LAMTOR4,CTSA,PSAP,ATP6V1C1,SNX14,SNAPIN |
| 5.809e-04 | -7.45 | lytic vacuole membrane | cellular component | GO:0098852 | 357 | 76 | 18223 | 2701 |
RAB14,ABCC10,AP1B1,ATP6V1B2,GNB2,CMTM6,CPNE3,GLMP,NAPG,AP1M1,CLCN6,BRI3,AP2B1,MARCH2,TMEM9,TMBIM1,SEH1L,DRAM2,ATP6V1G1,WDR41,CPNE1,MIOS,GOPC,RAB7A,ATP6V0A1,SLC17A5,RHEB,AHNAK,WDR11,SURF4,DDOST,WDR59,AP1S1,ATP6V0C,SCARB1,CLN3,AP2S1,STARD3NL,DNAJC5,ANXA6,CCZ1,MANBA,CDIP1,FLOT1,LAMTOR3,B4GALT1,TMEM165,PSEN1,TMEM179B,SPPL2A,ZNRF2,ATP6V0A2,TMEM8A,LPCAT1,ATP6V0D1,TPCN1,MFSD12,ACP2,GBA,WDR81,SPPL2B,RMC1,NEU1,PI4K2A,SCARB2,ATP6V1D,MAGT1,NSF,CCZ1B,SNAP29,LAMTOR4,CTSA,PSAP,ATP6V1C1,SNX14,SNAPIN |
| 5.826e-04 | -7.45 | ARM-like | interpro domains | IPR011989 | 191 | 46 | 18492 | 2768 |
NOP9,PKP4,TRIP12,SF3B1,SCYL1,DNAAF5,XPO7,AP1B1,NCAPG,COPG2,SCYL2,HEATR5B,ZER1,CEP104,PSMD2,PSMD1,CTNNBL1,PPP4R1,TNPO2,AP2B1,LTN1,TNPO3,KIFAP3,SCYL3,USO1,BTAF1,LRBA,TEX10,ARID1A,ARMC8,AP4E1,SYMPK,CIP2A,CAND1,CNOT9,INF2,KPNA4,KPNA1,HSPBP1,PLAA,PPP2R5A,ELMO1,CAB39,SIL1,KPNA2,ECPAS |
| 5.828e-04 | -7.45 | RHO GTPases activate KTN1 | REACTOME pathways | R-HSA-5625970 | 11 | 7 | 10287 | 1696 |
KLC1,KIF5B,RHOG,RHOA,CDC42,KTN1,RAC1 |
| 5.842e-04 | -7.45 | MAP2K1 (mitogen-activated protein kinase kinase 1) | protein interactions | 5604 | 93 | 28 | 17029 | 2761 |
PLK3,CPNE1,SKA3,BRD4,VHL,RAF1,LAMTOR3,BRAP,KRAS,BLM,ELK1,UBE2I,MAPK14,MAP2K2,MAPK3,CDK5,VAV1,MAP3K4,PTPN11,DCP1A,STK11,YWHAZ,ARRB2,MAPK1,PDLIM5,HRAS,POC5,HDAC2 |
| 5.842e-04 | -7.45 | CDK16 (cyclin dependent kinase 16) | protein interactions | 5127 | 93 | 28 | 17029 | 2761 |
SNX27,NF1,FAM53C,DENND4C,NUP54,CSNK2A1,BRCA1,RAB3IP,PKM,PRKACA,APP,USP21,GIGYF1,LMNA,EDC3,GTF2F1,RTKN,CDK5,AFDN,ZBTB21,FAM110A,KIF13B,YWHAZ,CDC25B,CDK2,YWHAH,MCMBP,PPP2R2D |
| 5.845e-04 | -7.44 | skin-carcinoma-squamous_cell_carcinoma | COSMIC cancer mutations | skin-carcinoma-squamous_cell_carcinoma | 498 | 101 | 17385 | 2587 |
DNMT3A,CYLD,NQO1,TSC2,ARID2,ADAM10,NF1,SF3B1,RAF1,PMS2,VTI1A,SMARCA4,MYH9,LYN,EXT2,FANCI,TET3,FANCL,ABL2,CRKL,ANKLE1,MDM2,IL6ST,ETV6,CDKN1B,TFG,DNMT1,CDK12,ABI1,SZRD1,NRAS,SEPT9,BIRC3,AKT2,VHL,GOPC,ATXN1,MCL1,BRCA1,AURKB,PBRM1,KMT2C,FANCE,ERC1,DOT1L,WAS,SMAD2,JAK1,AXIN1,STK11,TRAF5,MAPK1,SMAD4,FUBP1,POU3F2,EWSR1,AGTRAP,MYNN,NOTCH2,BLM,IL21R,CDC73,FOXO3,HLA-A,TFRC,FGFR3,RPN1,RB1,PTEN,ATIC,AXIN2,PTPN11,AFF1,BCL2,MSH6,SPTAN1,PDPK1,TNFAIP3,CIC,ACSL3,MAN1B1,KRAS,ARID1A,MAP2K2,FAS,GNAS,SEC31A,TSC1,SLC19A1,HLA-B,KEAP1,PALB2,CCDC6,TFDP1,MED15,SIL1,DDX5,MAP3K5,HRAS,C7orf26,CDKN2A |
| 5.846e-04 | -7.44 | GSE17186_BLOOD_VS_CORD_BLOOD_NAIVE_BCELL_DN | MSigDB lists | GSE17186_BLOOD_VS_CORD_BLOOD_NAIVE_BCELL_DN | 179 | 44 | 17377 | 2626 |
MIF,TCF12,GALK1,ADD1,RPLP2,HMGXB3,FAM8A1,SAC3D1,MAT2B,SIAH1,DAD1,HDAC7,ARHGEF1,ZNF260,HADHB,PDCD2,TTLL12,FRMD8,ANKRD9,RPL22L1,TMEM9,TPCN1,SMC4,METTL1,ERCC1,SEPT9,ERF,KIAA0040,SELPLG,EZR,RFFL,ESYT1,GALNT7,ICAM2,USP36,UTP20,JAK1,FASTK,RPLP1,SMG9,GALNT10,CBX4,GPATCH4,ESYT2 |
| 5.846e-04 | -7.44 | GSE27786_LSK_VS_BCELL_UP | MSigDB lists | GSE27786_LSK_VS_BCELL_UP | 179 | 44 | 17377 | 2626 |
TMEM106C,SLC12A7,PIGN,TM9SF4,AGTRAP,WDYHV1,ANKH,MAPK14,EXT2,FBXO3,ANKRD26,GSTK1,DDX56,PDXP,ORAI1,TTC3,UBE3B,ALDH18A1,CNNM3,TMBIM1,MLST8,ENPP4,TELO2,PHF10,PRIM2,AATF,RAD51AP1,LDB1,NSUN2,CCDC34,SEPT8,CCNF,TRIM28,GLOD4,PRIM1,AMZ2,UTP20,DNAJC10,GALNT2,HAGHL,RUVBL2,PDXK,C11orf1,ANXA11 |
| 5.846e-04 | -7.44 | GSE22432_UNTREATED_VS_TGFB1_TREATED_COMMON_DC_PROGENITOR_DN | MSigDB lists | GSE22432_UNTREATED_VS_TGFB1_TREATED_COMMON_DC_PROGENITOR_DN | 179 | 44 | 17377 | 2626 |
OTUD5,CDS2,PPP1R12A,CKLF,UGP2,CIB1,SLC25A12,SIKE1,MAN2B1,CDC42SE2,TMED3,IKBIP,PRKACA,IFT27,SDHA,COPG2,FERMT3,TNS3,DPYSL2,PPCDC,ANP32A,TAP2,FAM3A,TMEM9,ARID4A,GPX4,BIRC3,PRIM2,BTG2,PPP1R21,NARF,AURKB,DHX57,ECH1,ZMYM3,CTBS,MYO18A,GLG1,CD81,C11orf1,TOB1,PDCD4,HIGD2A,ZBTB24 |
| 5.846e-04 | -7.44 | GSE13411_PLASMA_CELL_VS_MEMORY_BCELL_UP | MSigDB lists | GSE13411_PLASMA_CELL_VS_MEMORY_BCELL_UP | 179 | 44 | 17377 | 2626 |
PPIB,TMEM184B,CDT1,PTTG1,TPX2,CDCA3,PXMP2,SDF2L1,SLC35B1,FKBP2,NCAPG,SPAG5,CCNA2,RRBP1,NOC2L,LMAN1,LYPLA2,KDELR1,CLPTM1,TK1,PSRC1,TIMP2,SEC61B,ELL2,MKI67,RRM2,AURKB,SLC17A5,VKORC1,COMMD4,NEU1,OPTN,SEC61A1,KIF18B,WNT5B,SEL1L,ATF6,WDR76,CCNB2,XRCC4,UBE2C,E2F2,CDKN2A,DYNC1LI2 |
| 5.846e-04 | -7.44 | GSE18791_CTRL_VS_NEWCASTLE_VIRUS_DC_16H_UP | MSigDB lists | GSE18791_CTRL_VS_NEWCASTLE_VIRUS_DC_16H_UP | 179 | 44 | 17377 | 2626 |
NCOR2,PRPF38B,TP53RK,URB2,SHPRH,MRI1,UROD,PCSK7,SLC25A12,EBNA1BP2,COMMD8,PCYOX1L,PSMD2,SNUPN,GATC,ATP2A2,CWC27,PTPN11,NSFL1C,MSH2,GPATCH1,CTR9,TARDBP,HNRNPM,TIMM50,NAGPA,DDX28,RFC3,ZNF559,FAM172A,DHX29,WDR1,MRS2,GMFB,SCFD2,GAR1,LSG1,DHX15,BTBD1,PDCD6,PRPS2,PITPNA,TRIM32,RUVBL2 |
| 5.914e-04 | -7.43 | pigment granule | cellular component | GO:0048770 | 106 | 29 | 18223 | 2701 |
PPIB,ANKRD27,DNAJC5,PDCD6IP,ANXA6,RAB7A,RAC1,SLC2A1,FLOT1,ATP6V0A1,SND1,RAB1A,ATP6V1B2,RAB5B,PRDX1,TFRC,RPN1,NAP1L1,ATP1A1,SLC1A4,TMED10,RAB35,ITGB1,YWHAZ,AHCY,PDIA6,MYO5A,ANXA11,TMEM33 |
| 5.914e-04 | -7.43 | melanosome | cellular component | GO:0042470 | 106 | 29 | 18223 | 2701 |
PPIB,ANKRD27,DNAJC5,PDCD6IP,ANXA6,RAB7A,RAC1,SLC2A1,FLOT1,ATP6V0A1,SND1,RAB1A,ATP6V1B2,RAB5B,PRDX1,TFRC,RPN1,NAP1L1,ATP1A1,SLC1A4,TMED10,RAB35,ITGB1,YWHAZ,AHCY,PDIA6,MYO5A,ANXA11,TMEM33 |
| 5.927e-04 | -7.43 | Fc-gamma receptor signaling pathway involved in phagocytosis | biological process | GO:0038096 | 71 | 22 | 17256 | 2622 |
WASF2,CYFIP1,NCK1,RAC1,ACTR3,VAV2,WIPF1,NCKAP1,CYFIP2,ARPC1A,LYN,MAPK3,VAV1,WAS,CDC42,ARPC5,ELMO1,LIMK1,PIK3R2,ACTB,MAPK1,ABI1 |
| 5.927e-04 | -7.43 | ribosomal large subunit biogenesis | biological process | GO:0042273 | 71 | 22 | 17256 | 2622 |
PPAN,DDX28,RPL35,NOP2,RRP15,WDR18,RPL6,GTPBP4,RPL38,GTF3A,EBNA1BP2,BRIX1,MAK16,RPL23A,RPL11,NSA2,NIP7,NOC2L,RPF2,RRS1,MRPL11,FTSJ3 |
| 5.927e-04 | -7.43 | glycosphingolipid metabolic process | biological process | GO:0006687 | 71 | 22 | 17256 | 2622 |
GALC,HEXB,CERK,GBA,ASAH1,SUMF1,ESYT1,ARSK,NEU1,CREM,ITGB8,GLTP,CTSA,SMPD4,PSAP,ST8SIA2,B4GALT3,CLN3,HEXA,CLN6,GM2A,ESYT2 |
| 5.927e-04 | -7.43 | DNA duplex unwinding | biological process | GO:0032508 | 71 | 22 | 17256 | 2622 |
GINS1,RECQL,RBX1,HELB,TWNK,CHD1L,DHX9,BLM,MCM2,CHD1,GINS4,RAD54B,XRCC5,CHD3,RPS27A,XPA,RAD23B,RUVBL2,GTF2H2,POT1,PURA,DDB1 |
| 5.927e-04 | -7.43 | regulation of nucleotide catabolic process | biological process | GO:0030811 | 71 | 22 | 17256 | 2622 |
NDC1,NUP188,RAE1,PRKAA1,NUP54,PFKFB3,NUP155,NUP205,NUP210,TIGAR,NUP107,OGT,NUP62,NUP153,ECD,PGAM1,STAT3,NUP58,NUP85,AAAS,SEH1L,EGLN1 |
| 5.927e-04 | -7.43 | ribosomal small subunit biogenesis | biological process | GO:0042274 | 71 | 22 | 17256 | 2622 |
RPS15,RPS10,RPL38,RPS24,BMS1,UTP3,TSR2,RRP36,RPSA,KRR1,KRI1,UTP25,UTP20,NOL11,LSM6,UTP18,RPS14,TBL3,RRS1,PDCD11,UTP4,BYSL |
| 5.927e-04 | -7.43 | immune response-regulating cell surface receptor signaling pathway involved in phagocytosis | biological process | GO:0002433 | 71 | 22 | 17256 | 2622 |
WASF2,CYFIP1,NCK1,RAC1,ACTR3,VAV2,WIPF1,NCKAP1,CYFIP2,ARPC1A,LYN,MAPK3,VAV1,WAS,CDC42,ARPC5,ELMO1,LIMK1,PIK3R2,ACTB,MAPK1,ABI1 |
| 5.938e-04 | -7.43 | FAM131B (family with sequence similarity 131 member B) | protein interactions | 9715 | 31 | 13 | 17029 | 2761 |
PLK1,TIMM29,MBLAC2,ATP6V0A1,ATP6V0A2,UQCRH,CDC6,UHRF1BP1,MYO9B,NCOA1,FAM208A,POT1,SEH1L |
| 5.938e-04 | -7.43 | LAP3 (leucine aminopeptidase 3) | protein interactions | 51056 | 31 | 13 | 17029 | 2761 |
MIF,RAB7A,DDA1,UBA5,TKT,OGT,AGFG1,NDUFS5,APP,SH3GLB1,PRDX1,ISG15,FUBP1 |
| 5.938e-04 | -7.43 | PRPSAP1 (phosphoribosyl pyrophosphate synthetase associated protein 1) | protein interactions | 5635 | 31 | 13 | 17029 | 2761 |
RPL35,TMBIM4,IVNS1ABP,PRPS2,PTP4A3,DDX5,SMG9,PRKRA,MAPK1,PRPSAP1,PLEKHF2,UBLCP1,DDX17 |
| 5.938e-04 | -7.43 | TFAM (transcription factor A, mitochondrial) | protein interactions | 7019 | 31 | 13 | 17029 | 2761 |
NRF1,CYLD,AGTRAP,GOPC,SUZ12,GRSF1,ARL6IP1,CUL3,KCTD17,NFATC2,SDHA,RPA1,CAND1 |
| 5.938e-04 | -7.43 | LIN37 (lin-37 DREAM MuvB core complex component) | protein interactions | 55957 | 31 | 13 | 17029 | 2761 |
LIN9,RB1,HSPA4,EWSR1,FOXM1,RBL1,E2F4,TFDP1,MYBL2,RBBP4,TFDP2,CDK2,MYBL1 |
| 5.938e-04 | -7.43 | WIPI2 (WD repeat domain, phosphoinositide interacting 2) | protein interactions | 26100 | 31 | 13 | 17029 | 2761 |
TERF2IP,TIMM13,HUWE1,TXLNA,STRN4,ARL6IP1,DNM2,DNAJB1,COPS6,POT1,PFKP,OPTN,NUDC |
| 5.938e-04 | -7.43 | LIN9 (lin-9 DREAM MuvB core complex component) | protein interactions | 286826 | 31 | 13 | 17029 | 2761 |
LIN9,RB1,PHF20L1,FOXM1,RBL1,E2F4,TFDP1,MYBL2,RPN2,TFDP2,RBBP4,MYBL1,TCF19 |
| 5.948e-04 | -7.43 | HSF1 (heat shock transcription factor 1) | protein interactions | 3297 | 125 | 35 | 17029 | 2761 |
DHPS,IVNS1ABP,SMC6,CSNK2A1,SMARCA4,DNAJB1,UBE2I,REPS1,SUB1,MTA1,EFTUD2,BTF3L4,PTGES3,LRSAM1,CARMIL1,STRAP,PLK1,RPRD1A,MAPRE2,GOPC,PRKDC,MCM2,SYMPK,MAPK3,XRCC5,HSPA4,HSPBP1,KPNA4,CHD3,STAT1,FKBP5,DTD1,CFAP20,MAPK1,HDAC2 |
| 5.958e-04 | -7.43 | cellular response to reactive oxygen species | biological process | GO:0034614 | 123 | 33 | 17256 | 2622 |
NQO1,PRKAA1,PXMP2,BECN1,ETS1,PARK7,CFLAR,PDK2,PDCD10,CCNA2,PCNA,MDM2,DNM2,PTPRK,PPIF,TNFAIP3,NET1,MTR,PRDX1,RHOB,MAPK3,ANKZF1,PRDX3,STAT6,GUCY1B1,PRDX5,MPV17,PKD2,PPP5C,MAP3K5,MAPK1,CDK2,HDAC2 |
| 5.974e-04 | -7.42 | MORF_XPC | MSigDB lists | MORF_XPC | 58 | 19 | 17377 | 2626 |
DPM1,RAF1,PDAP1,RAC1,RAB1A,PRPSAP1,RAB11A,SDHA,HUWE1,ARF5,RAD23B,COX7A2L,HADHB,GLG1,COX5A,WIPI2,COPS6,CLN3,COIL |
| 5.988e-04 | -7.42 | REACTOME_G2_M_CHECKPOINTS | MSigDB lists | REACTOME_G2_M_CHECKPOINTS | 41 | 15 | 17377 | 2626 |
RPA2,RFC3,MCM10,MCM5,DBF4,CDC6,CHEK2,ORC1,MCM2,CCNB1,ORC3,CDK2,RFC2,CCNB2,RPA1 |
| 6.009e-04 | -7.42 | protein-containing complex binding | molecular function | GO:0044877 | 971 | 186 | 17224 | 2647 |
MAX,H2AFZ,ADD1,ST13,ADAM10,YTHDF3,SNRPD3,S1PR2,PRNP,DST,ABL2,PCNA,RAP1A,SYNM,EIF4A3,RCSD1,NOC2L,DNM2,AP2B1,SMARCE1,CARMIL1,TIMM50,ELOF1,PLK1,SRP72,NRAS,GMFB,PSMG1,EZR,KRIT1,PAF1,GEMIN5,WAS,RAD18,TMED10,RPS27A,MYO18A,ITGB1,PQBP1,ADAM9,ACTB,RNASEL,CLU,ARRB2,SLF1,ZNF598,NMD3,HDAC2,PFKP,ANXA11,PPIB,CLSPN,GMFG,HLA-E,MUM1,CENPF,DHX9,STRN4,NDUFA4,TOP2B,NCKAP1,CDC73,JMY,FKBP1A,SMC3,ARPC5,MBD2,MSH2,ZNF326,CTR9,RNF135,GNAI2,TERF2,HP1BP3,EIF5A,CYFIP1,DHX29,WDR1,MTA2,KRAS,RTF1,EIF2A,ARID1A,ADRB2,PKM,ICAM2,ARPC1A,EIF4H,ISG15,PHF6,HMGN2,PI4K2A,XRCC5,GNAS,PTPRF,NSF,PRMT7,CABIN1,RBBP4,SNRNP70,APOL2,WASF2,ACTR3,PMS2,SMARCA4,MYH9,EFL1,LYN,TWF2,GNB2,RPAIN,BCAP31,MDM2,SHC1,NVL,UCHL5,MRPS27,CDKN1B,RPN2,CORO1A,SAP30L,ABI1,RPRD1B,CFL1,RNF169,DCTN1,BRD4,HMGN4,RAB7A,ELP4,WIPF1,BICD2,ERBIN,MBD3,TMEM201,RPSA,SUPT16H,EIF3K,SEC61A1,CORO1C,TULP3,SCARB1,H3F3A,SMURF1,SMAD4,LRP8,TUBB,ATMIN,ADAM23,USP13,AGO2,LETMD1,SECISBP2,HMGN3,SPDL1,FERMT3,PTPN2,CTSS,PTEN,PELO,PTPN11,LTN1,H2AFY,NAP1L4,MYO5A,MSH6,PDPK1,TELO2,PPP1R9B,ADAM17,HMGN1,FAM49B,HMGN5,SNX2,KIF11,MACF1,SNRPA,CTSL,GNA12,LTBP4,LRPPRC,DDX5,CD81,CPEB2,SLF2,DDB1 |
| 6.026e-04 | -7.41 | CLTCL1 (clathrin heavy chain like 1) | protein interactions | 8218 | 67 | 22 | 17029 | 2761 |
IDH3A,CUTA,RPL6,CUL3,CUL1,RXYLT1,GALNT7,CAPZA2,SEC16A,CDC73,PICALM,CAND1,CTSL,HLA-B,EPRS,ATP1A1,HSPBP1,AHSA1,CCDC69,GTSE1,COPS6,CLTB |
| 6.026e-04 | -7.41 | RPL29 (ribosomal protein L29) | protein interactions | 6159 | 67 | 22 | 17029 | 2761 |
STAU1,RPS2,CYLD,EWSR1,MECP2,RPL6,RPL38,RPL8,ILF3,RPS24,BRCA1,RPSA,RPL23A,DDX56,RPL32,RPL17,CHD3,RPLP1,BTF3,RRS1,EIF5,RPS26 |
| 6.026e-04 | -7.41 | WDR36 (WD repeat domain 36) | protein interactions | 134430 | 67 | 22 | 17029 | 2761 |
NIFK,AATF,UBN1,MECP2,ABCF2,UTP15,GTPBP4,KRAS,RBM4,DHX15,USP36,KRR1,DDX56,DUS3L,MCM5,TBL3,EXOSC1,NOC2L,CTPS1,POLR1B,FBL,IFI16 |
| 6.035e-04 | -7.41 | RHO GTPases activate CIT | REACTOME pathways | R-HSA-5625900 | 17 | 9 | 10287 | 1696 |
RHOA,RHOC,KIF14,RAC1,PRC1,MYH9,CDKN1B,MYL12B,RHOB |
| 6.035e-04 | -7.41 | Polo-like kinase mediated events | REACTOME pathways | R-HSA-156711 | 17 | 9 | 10287 | 1696 |
LIN9,PLK1,FOXM1,CENPF,MYBL2,PKMYT1,CCNB1,RBBP4,CCNB2 |
| 6.040e-04 | -7.41 | chronic_pancreatitis | COSMIC cancer mutations | chronic_pancreatitis | 9 | 6 | 17385 | 2587 |
GNAS,KRAS,NRAS,HRAS,SMAD4,CDKN2A |
| 6.040e-04 | -7.41 | pancreas-other-chronic_pancreatitis | COSMIC cancer mutations | pancreas-other-chronic_pancreatitis | 9 | 6 | 17385 | 2587 |
GNAS,KRAS,NRAS,HRAS,SMAD4,CDKN2A |
| 6.040e-04 | -7.41 | coccyx | COSMIC cancer mutations | coccyx | 9 | 6 | 17385 | 2587 |
KRAS,EWSR1,NRAS,H3F3A,HRAS,CDKN2A |
| 6.040e-04 | -7.41 | soft_tissue-other-neoplasm | COSMIC cancer mutations | soft_tissue-other-neoplasm | 9 | 6 | 17385 | 2587 |
KRAS,FUS,EWSR1,NRAS,NF1,HRAS |
| 6.040e-04 | -7.41 | lung-carcinoma-adenoid_cystic_carcinoma | COSMIC cancer mutations | lung-carcinoma-adenoid_cystic_carcinoma | 9 | 6 | 17385 | 2587 |
KIF5B,RB1,KRAS,NRAS,CCDC6,HRAS |
| 6.048e-04 | -7.41 | skin-buttock-other-atypical_Spitzoid_tumour | COSMIC cancer mutations | skin-buttock-other-atypical_Spitzoid_tumour | 22 | 10 | 17385 | 2587 |
KIF5B,PWWP2A,NRAS,ZCCHC8,HRAS,ERC1,HLA-A,MYO5A,LMNA,DCTN1 |
| 6.048e-04 | -7.41 | skin-other-atypical_Spitzoid_tumour | COSMIC cancer mutations | skin-other-atypical_Spitzoid_tumour | 22 | 10 | 17385 | 2587 |
KIF5B,PWWP2A,NRAS,ZCCHC8,HRAS,ERC1,HLA-A,MYO5A,LMNA,DCTN1 |
| 6.048e-04 | -7.41 | skin-face-benign_melanocytic_nevus-Spitz | COSMIC cancer mutations | skin-face-benign_melanocytic_nevus-Spitz | 22 | 10 | 17385 | 2587 |
KIF5B,PWWP2A,NRAS,ZCCHC8,HRAS,ERC1,HLA-A,MYO5A,LMNA,DCTN1 |
| 6.048e-04 | -7.41 | skin-upper_arm-other-atypical_Spitzoid_tumour | COSMIC cancer mutations | skin-upper_arm-other-atypical_Spitzoid_tumour | 22 | 10 | 17385 | 2587 |
KIF5B,PWWP2A,NRAS,ZCCHC8,HRAS,ERC1,HLA-A,MYO5A,LMNA,DCTN1 |
| 6.048e-04 | -7.41 | skin-lower_leg-benign_melanocytic_nevus-Spitz | COSMIC cancer mutations | skin-lower_leg-benign_melanocytic_nevus-Spitz | 22 | 10 | 17385 | 2587 |
KIF5B,PWWP2A,NRAS,ZCCHC8,HRAS,ERC1,HLA-A,MYO5A,LMNA,DCTN1 |
| 6.048e-04 | -7.41 | skin-knee-benign_melanocytic_nevus-Spitz | COSMIC cancer mutations | skin-knee-benign_melanocytic_nevus-Spitz | 22 | 10 | 17385 | 2587 |
KIF5B,PWWP2A,NRAS,ZCCHC8,HRAS,ERC1,HLA-A,MYO5A,LMNA,DCTN1 |
| 6.055e-04 | -7.41 | GSE17974_0.5H_VS_72H_IL4_AND_ANTI_IL12_ACT_CD4_TCELL_DN | MSigDB lists | GSE17974_0.5H_VS_72H_IL4_AND_ANTI_IL12_ACT_CD4_TCELL_DN | 169 | 42 | 17377 | 2626 |
EXOC3,SKA3,FOXM1,MRPS15,DCAF15,GNPDA1,RMI2,LETMD1,HAUS4,SLC29A1,CCNB1,STMN1,CD320,KIFC1,SNUPN,BDH1,NUP107,MECR,GEMIN6,RNASEH2A,GLE1,METTL9,MSH6,ZNF672,TRAFD1,HPDL,MRPL12,LDHA,GLO1,FXR1,ANKZF1,RAD51C,KEAP1,SURF4,AGPAT2,PRDX3,ACTB,BTF3,TUBB,RAD51D,SNAPIN,POLQ |
| 6.055e-04 | -7.41 | GCNP_SHH_UP_LATE.V1_UP | MSigDB lists | GCNP_SHH_UP_LATE.V1_UP | 169 | 42 | 17377 | 2626 |
POLA2,MCM10,IVNS1ABP,SDC2,RRM1,YTHDF3,TM9SF3,USP39,TOP2B,SLC29A1,KIF2C,GFM2,CREM,KIFC1,CLIC4,GART,ZKSCAN1,MCM5,MBD2,PRC1,TARDBP,MOB1A,ARL5A,FTSJ3,SMC4,SRSF10,RLIM,TK1,MIOS,RRM2,NUSAP1,AURKB,EIF2A,DIDO1,SMC2,DDX39A,MATR3,SLTM,EIF3A,SRSF1,LUC7L3,COIL |
| 6.055e-04 | -7.41 | GSE9988_ANTI_TREM1_VS_VEHICLE_TREATED_MONOCYTES_UP | MSigDB lists | GSE9988_ANTI_TREM1_VS_VEHICLE_TREATED_MONOCYTES_UP | 169 | 42 | 17377 | 2626 |
KCTD7,TXN,GNPDA1,KLHL21,ADO,RGS1,SPAG5,SRXN1,ANKRD28,MOAP1,ABL2,DTL,HOMER1,SNUPN,IARS,NAA50,FNIP2,RNF19A,SLC26A2,ATP6V1G1,TCTEX1D2,KLF10,LONRF3,ACSL3,MAP4K3,RIT1,SLC17A5,RAB1A,TARS,RHEB,NEU1,SH3BP5,SLCO4A1,ETS2,UAP1,DUSP3,CORO1C,MAPK6,USP53,ZC3HC1,ESYT2,ADNP2 |
| 6.094e-04 | -7.40 | positive regulation of molecular function | biological process | GO:0044093 | 1736 | 311 | 17256 | 2622 |
TXN,TSC2,ADD1,MAP3K7CL,CCNL2,CCNB1,UBE2I,RIC1,ELMOD2,PARK7,CALM2,CDK5,ASAP2,RABGAP1L,RAB4A,DNM2,CDC25B,PLCL2,SENP1,MLST8,BAK1,AKT2,ARHGAP45,MRNIP,TOPORS,AURKB,DCUN1D5,RFC2,ARF4,KRIT1,MAP3K4,MID1IP1,RPS27A,AXIN1,ITGB1,TRIM52,TRAF5,NMD3,DDX58,HSPH1,MAPRE1,CLSPN,MUT,GMFG,CHTF18,RHOC,GADD45G,PRKAA1,VAV2,DHX9,ACAP1,CYCS,APH1B,PARN,PSEN1,JMY,CFLAR,DDRGK1,TFAP4,FKBP1A,SNX18,MSH2,DAPK1,GNAI2,TERF2,MAPKAPK3,MFNG,ADRB2,CYFIP2,MAP2K2,FAS,XRCC5,DERL1,CAT,FNTA,GOLGA2,CSK,CEBPG,ARAP1,CNOT6,MAP3K5,ALS2,RHOG,ANKRD27,KARS,RWDD1,TRIP10,RAF1,EIF3D,MAGED1,ANK3,TPX2,TBC1D13,DAZAP2,PRKACA,STMN1,APP,TERF2IP,CRKL,SHC1,SH3BP1,RALB,TBC1D22A,TBC1D14,ADCY9,CDKN1B,MAVS,ATF2,ADCY7,CCT2,PSRC1,RFC3,MAP4K4,TAOK1,EDF1,DNAJA1,RAB1A,ERC1,TRIM28,PPP2CA,CORO1C,HIPK2,RPLP1,TICAM1,TRIM32,PITRM1,XRCC4,LRP8,RHEBL1,RPS2,PKP4,DEPDC1,ZFP91,TCF3,FLOT1,GTF2F1,CCNK,PDCD10,PTEN,AHSA1,ARHGEF1,PTPN11,AXIN2,DCP1A,MAP3K14,MSH6,PDPK1,PPP3CA,KAT2A,DENND1B,NEK7,NET1,JTB,MARK2,PICALM,FADD,SMAP2,PRDX3,PML,HMGB2,PSAP,CD81,CCNC,AGRN,NF1,PPP1R15B,DNAJC24,SIRT2,AGFG1,S1PR2,MAPK14,GIT2,PRNP,ABL2,RAP1A,PCNA,PIK3R2,RP2,TCEA1,EIF5,MTPN,CARM1,TRIM14,PLK1,COPS8,LARS,TRIM8,APH1A,GMFB,UBE2V1,LRP5,ARHGDIB,CDC6,PRKRA,EPB41,TBC1D17,MIA2,ADAM9,CAB39,STK11,CLU,POT1,TBC1D12,PPP1R12A,GORASP1,PHB2,DNAJB2,LAMTOR3,CIB1,RACGAP1,DNAJB1,DOCK11,RGS2,RAPGEF6,APOPT1,RB1,NUS1,TIGAR,RINL,MBD2,BUD31,BCL2,MDFIC,PREB,TRAPPC9,MAP4K3,KRAS,ARHGAP15,TSC1,CTSA,MYO9A,NIPSNAP2,KCTD7,IFI27L1,TRAF7,DYNLL1,TOR1AIP1,SMARCA4,LYN,BCAP31,RPL11,HNRNPA2B1,VAV1,PSMA6,NVL,KIF14,PIN1,PDCD2,CHTOP,F2R,ABI1,GM2A,HTRA2,DNAL4,DVL2,CHP1,ARHGAP17,TIMP2,RNF25,DNAJC9,TOR1AIP2,AFDN,DNAJC10,TAB2,GADD45B,SCARB1,CCDC125,MAPK1,MIF,DNAJC2,GCLM,SMAP1,DAP,CDT1,DBF4,MYO9B,DCUN1D4,RGS1,FBXO5,KIF5B,IRF4,FGFR3,CTSS,TANK,ARHGEF2,ATG13,PTGES3,STAT3,TGFB1,TELO2,RHOA,HMGN1,ADAM17,PRKAR1B,ARHGEF12,RANGAP1,MEN1,HSPA1B,MAPK3,CNOT9,NEK1,PDCD6,TRIM26,PLAA,OSBPL8,PKD2,TAF12,UBE2C,ARHGAP23,HRAS,IFI16 |
| 6.113e-04 | -7.40 | REACTOME_PRE_NOTCH_EXPRESSION_AND_PROCESSING | MSigDB lists | REACTOME_PRE_NOTCH_EXPRESSION_AND_PROCESSING | 37 | 14 | 17377 | 2626 |
ATP2A2,KAT2A,TFDP1,SEL1L,MFNG,E2F1,E2F3,B4GALT1,NOTCH2,RAB6A,RBPJ,MAML1,POFUT1,TMED2 |
| 6.113e-04 | -7.40 | GCM_AIP | MSigDB lists | GCM_AIP | 37 | 14 | 17377 | 2626 |
UBE2D3,VAV1,PLK1,ZNF76,WAS,SIGMAR1,POLR2K,DHPS,TIMM17A,DRAP1,ARHGEF1,TTF1,BCAT2,ABCC1 |
| 6.113e-04 | -7.40 | PID_GMCSF_PATHWAY | MSigDB lists | PID_GMCSF_PATHWAY | 37 | 14 | 17377 | 2626 |
NRAS,SHC1,RAF1,STAT1,PTPN11,KRAS,YWHAZ,PRKACA,LYN,MAPK1,STAT3,HRAS,MAP2K2,MAPK3 |
| 6.113e-04 | -7.40 | GO_REGULATION_OF_DNA_TEMPLATED_TRANSCRIPTION_ELONGATION | MSigDB lists | GO_REGULATION_OF_DNA_TEMPLATED_TRANSCRIPTION_ELONGATION | 37 | 14 | 17377 | 2626 |
PAF1,HMGN1,BRD4,THOC1,ZMYND11,AXIN1,LDB1,ZNF326,CTR9,RTF1,TCEA1,CDC73,SUPT16H,GTF2F1 |
| 6.136e-04 | -7.40 | MBD | pfam domains | PF01429 | 9 | 6 | 17054 | 2545 |
MBD1,MBD3,BAZ2A,MECP2,MBD2,MBD4 |
| 6.141e-04 | -7.40 | KYNG_RESPONSE_TO_H2O2 | MSigDB lists | KYNG_RESPONSE_TO_H2O2 | 67 | 21 | 17377 | 2626 |
PRKCSH,EID1,SRGN,TCF3,TAP1,PTP4A3,PLXNA1,DNAJA1,DNAJB1,HCFC1R1,SLC20A1,PSMC4,CD59,PFDN5,CTSS,CCNA2,DUT,OAZ2,MPV17,CD81,DDX52 |
| 6.146e-04 | -7.39 | V$E2F_Q2 | MSigDB lists | V$E2F_Q2 | 164 | 41 | 17377 | 2626 |
SNX27,FAM129A,ADO,UROD,FAM76A,RRAGC,ORC1,USP48,RLF,STMN1,PIP4K2A,CDC73,ATPAF1,PABPC4,CSDE1,USF1,MED8,SUV39H2,CDC42,CAPZA1,MAST2,PLK3,CELSR2,CSRP1,APH1A,VDAC2,RABIF,UBE4B,SMAP2,NCDN,HMGN2,DAP3,PPP2R5A,HNRNPR,CCDC6,ANP32E,UQCRH,RBBP4,LRP8,B4GALT2,ATXN7L2 |
| 6.171e-04 | -7.39 | Mitochondrial protein import | REACTOME pathways | R-HSA-1268020 | 62 | 21 | 10287 | 1696 |
TIMM8B,TOMM20,TIMM21,SLC25A12,CHCHD2,MTX1,ATP5F1B,TOMM40,VDAC1,TAZ,GFER,CHCHD3,TIMM13,TIMM23,TOMM6,TIMM17A,CS,CYC1,ATP5F1A,MTX2,TIMM50 |
| 6.177e-04 | -7.39 | Calml3 (calmodulin-like 3) | protein interactions | 70405 | 144 | 39 | 17029 | 2761 |
PPP1R12A,LUZP1,PHB2,ACTR3,KIF23,RACGAP1,SEC16A,LYN,MYL6B,DST,GART,ADD3,CCDC50,CDC42,CAPZA1,AP2B1,CLTB,GNAI2,CFL1,CAMK2G,MYO5A,SPTAN1,PPP1R9B,RHOA,PPP1R18,ERLIN1,WDR1,NLN,PLEC,MACF1,PICALM,CHCHD3,GNAS,INF2,AHNAK,CORO1C,MYO18A,HMGB2,NDE1 |
| 6.194e-04 | -7.39 | Viral mRNA Translation | REACTOME pathways | R-HSA-192823 | 92 | 28 | 10287 | 1696 |
RPS15,RPL29,RPL35,RPS2,RPLP2,RPL8,RPS10,RPL6,RPL38,RPL15,RPS24,RPL27A,RPS9,RPSA,RPL11,RPL23A,RPL36,RPL37,RPL32,RPL17,RPS27A,RPS14,GRSF1,RPLP1,RPL19,FAU,RPS26,RPL22L1 |
| 6.194e-04 | -7.39 | Unfolded Protein Response (UPR) | REACTOME pathways | R-HSA-381119 | 92 | 28 | 10287 | 1696 |
EXOSC6,SEC61B,ADD1,SEC61G,CXXC1,EXOSC9,SYVN1,PARN,SERP1,LMNA,DNAJB9,SSR1,YIF1A,SEC31A,EXOSC7,SHC1,SEC61A1,TATDN2,EXOSC1,KHSRP,ASNA1,ATF6,MYDGF,PDIA6,CTDSP2,ATP6V0D1,PREB,DCTN1 |
| 6.206e-04 | -7.38 | cytosolic proteasome complex | cellular component | GO:0031597 | 12 | 7 | 18223 | 2701 |
UBQLN4,PSMD2,PSMD1,IDE,PSMC1,UCHL5,PSMC4 |
| 6.226e-04 | -7.38 | GSE6259_FLT3L_INDUCED_33D1_POS_DC_VS_CD4_TCELL_DN | MSigDB lists | GSE6259_FLT3L_INDUCED_33D1_POS_DC_VS_CD4_TCELL_DN | 159 | 40 | 17377 | 2626 |
RPS15,MCM10,CLSPN,MDH2,OLA1,POMP,BZW2,ERH,PA2G4,STRBP,HUWE1,CS,GTSE1,YBX1,RBM3,OSTF1,CNN2,FGFR1OP2,PDCL3,ZDHHC18,NET1,GTPBP4,DNAJC9,EDF1,GSTCD,GINS4,RPSA,HAUS8,MTHFD2,EIF4ENIF1,POLE,SERF2,TULP3,PPM1G,CCDC69,PPP1R11,LY75,CNOT6,SNRPG,GEN1 |
| 6.226e-04 | -7.38 | GSE3565_CTRL_VS_LPS_INJECTED_SPLENOCYTES_DN | MSigDB lists | GSE3565_CTRL_VS_LPS_INJECTED_SPLENOCYTES_DN | 159 | 40 | 17377 | 2626 |
MIF,RPS2,DNMT3A,ADD1,KLF13,PCBP1,RAPGEF6,PIP4K2A,TFRC,VASP,CTNNBL1,IL6ST,ZNHIT6,RCSD1,FBL,N4BP2,SMC4,RPL29,ELOVL5,ETV3,RPL8,RPS10,ITM2A,RAB3IP,TANC1,LY6E,GAR1,EIF3G,RPL36,GNAS,PRPS2,FAM3C,COX7A2L,RPLP1,RPS26,USP53,ACSF2,EYA2,GPATCH4,TMEM131 |
| 6.226e-04 | -7.38 | GSE27859_MACROPHAGE_VS_CD11C_INT_F480_HI_MACROPHAGE_DN | MSigDB lists | GSE27859_MACROPHAGE_VS_CD11C_INT_F480_HI_MACROPHAGE_DN | 159 | 40 | 17377 | 2626 |
WSB2,IVNS1ABP,KLHL21,RPS6KA1,DAP,MUM1,MRI1,PMS2,CERK,RPAIN,FBXL6,NEK6,INPP5A,PPP1R12C,AP1M1,TECR,ALDH18A1,CTDSP2,TPCN1,MED22,CAMK2G,ELOF1,ELOVL5,AMD1,DNAJC9,ATP6V0A1,FANCE,TAZ,ECH1,MAPK3,AKAP1,MOSPD3,ITPRIPL1,HINT1,CORO1C,PTPN7,CHEK2,USF2,TSPAN5,GCSH |
| 6.226e-04 | -7.38 | HALLMARK_APOPTOSIS | MSigDB lists | HALLMARK_APOPTOSIS | 159 | 40 | 17377 | 2626 |
CYLD,ADD1,CASP6,DAP,ANKH,TAP1,XIAP,BCL2L1,PSEN1,SLC20A1,BCAP31,APP,LMNA,CFLAR,EBP,CDKN1B,CDC25B,F2R,SPTAN1,GPX4,TIMP2,BIRC3,PPT1,BTG2,VDAC2,MCL1,DNAJA1,BRCA1,RHOT2,RHOB,FAS,DAP3,GADD45B,PPP3R1,HMGB2,ROCK1,RNASEL,CLU,CDK2,PDCD4 |
| 6.243e-04 | -7.38 | E2F-DP_heterodim | interpro domains | IPR037241 | 9 | 6 | 18492 | 2768 |
TFDP2,E2F2,E2F4,TFDP1,E2F1,E2F3 |
| 6.243e-04 | -7.38 | Myb_dom | interpro domains | IPR017930 | 9 | 6 | 18492 | 2768 |
MYBL1,TERF1,SNAPC4,MYBL2,TERF2,CDC5L |
| 6.310e-04 | -7.37 | GO_POSITIVE_REGULATION_OF_CELL_DIVISION | MSigDB lists | GO_POSITIVE_REGULATION_OF_CELL_DIVISION | 124 | 33 | 17377 | 2626 |
TGFB1,PLK1,KIF3B,PKP4,RHOA,GORASP1,PHB2,CUL3,KIF23,RACGAP1,LRP5,NUSAP1,CDC6,SIRT2,AURKB,RAB1A,BECN1,FBXO5,CAT,RB1,GOLGA2,CDC42,PTEN,BIRC5,NSMCE2,KIF14,CDCA5,H2AFY,YBX1,CDC25B,UBE2C,TERF1,ESPL1 |
| 6.317e-04 | -7.37 | GTGACGY_V$E4F1_Q6 | MSigDB lists | GTGACGY_V$E4F1_Q6 | 612 | 122 | 17377 | 2626 |
NF1,ADAM10,TSC22D3,ALKBH5,AGPAT1,SLC39A13,ENSA,ADPGK,CNTROB,UBQLN2,S1PR2,C2orf49,BECN1,ZADH2,PRKACA,MIEN1,LCLAT1,GNB2,SLC25A37,ZER1,CSDE1,DST,KDM2A,THADA,XRCC2,FIZ1,PPP6C,TRA2B,INTS12,JOSD1,CRY2,FAM76B,RLIM,ZNF524,ERF,KAT7,RAB7A,DNAJC9,GALK2,DNAJA1,OGDH,PBRM1,HERPUD2,GSTCD,FOXRED1,ERC1,ARF4,SRSF1,C1orf122,RAD51C,FBXO28,SPATA2,STT3A,ZNF367,CEP55,ATP6V0C,PRPF4,FAU,ZBTB11,LRP8,PTOV1,UBE2D3,NAT14,PKP4,ZCCHC9,GGA1,CDK2AP2,UFC1,DBF4,CTCF,MYNN,SECISBP2,DCUN1D4,RLF,TMEM165,PDXDC1,TFRC,WDR48,GTF2F1,SLC31A1,NDUFV1,VMP1,SSBP3,TAGLN2,CREB1,STAT3,ATP6V0D1,RNF5,KDELR1,TERF2,ABCC1,YTHDC1,EIF5A,ELOVL5,RPRD1A,ELL2,DHX29,BTAF1,WDR1,AMD1,C1orf35,WDR81,THNSL1,SRSF5,PNPLA8,ADRB2,TOMM40,ZFR,MASTL,GNAS,RAB18,TMEM127,NEK1,GOLGA2,ODF2,MAPK6,DCAF11,PPP1R11,ZNF830,EHD4,SMARCD1,ADNP2 |
| 6.324e-04 | -7.37 | LIN54 (lin-54 DREAM MuvB core complex component) | protein interactions | 132660 | 24 | 11 | 17029 | 2761 |
LIN9,RB1,FOXM1,RBL1,E2F4,TFDP1,MYBL2,RPN2,RBBP4,TFDP2,MYBL1 |
| 6.324e-04 | -7.37 | ARNTL2 (aryl hydrocarbon receptor nuclear translocator like 2) | protein interactions | 56938 | 24 | 11 | 17029 | 2761 |
NOP9,MDM2,NSMCE4A,CIPC,PTTG1,ARNTL,DHTKD1,HAUS4,MCM2,METTL3,SSRP1 |
| 6.324e-04 | -7.37 | CHMP3 (charged multivesicular body protein 3) | protein interactions | 51652 | 24 | 11 | 17029 | 2761 |
CHMP2A,CHMP4A,VAV2,TNPO3,CHMP4B,VPS4A,SMAD1,CHMP2B,TFG,RAB11A,APP |
| 6.324e-04 | -7.37 | RWDD2B (RWD domain containing 2B) | protein interactions | 10069 | 24 | 11 | 17029 | 2761 |
PHC2,GOLPH3L,GADD45G,DNM2,ARMT1,BRCA1,PDLIM5,APP,DCAF5,SRPK2,EPB41 |
| 6.324e-04 | -7.37 | CEPT1 (choline/ethanolamine phosphotransferase 1) | protein interactions | 10390 | 24 | 11 | 17029 | 2761 |
AFDN,CYLD,CDC42,SMC6,XRCC3,KIF22,TOMM40,WDR62,PSMC1,QSOX2,OAZ1 |
| 6.335e-04 | -7.36 | GSE360_CTRL_VS_L_DONOVANI_MAC_DN | MSigDB lists | GSE360_CTRL_VS_L_DONOVANI_MAC_DN | 190 | 46 | 17377 | 2626 |
WSB2,TXN,LUZP1,URB2,CDK2AP2,UCK2,LETMD1,TGOLN2,BCL2L1,GGPS1,PDXDC1,DNAJB9,MOAP1,HNRNPA2B1,TFAP4,ADD3,RABGAP1L,CAPZA1,TTC3,MDFIC,CLDND1,TP53BP2,MICAL3,KDELR1,CPNE1,DHX29,NFATC2IP,CCNF,ODC1,MACF1,PDHX,DHX15,ANKRD46,MAT2A,ZFR,ABHD5,SH3BP5,VEZF1,STT3A,TAB2,SNAP23,CTBS,PPP1R11,MAP3K5,PDLIM5,TRAF5 |
| 6.335e-04 | -7.36 | GSE17721_LPS_VS_GARDIQUIMOD_0.5H_BMDC_UP | MSigDB lists | GSE17721_LPS_VS_GARDIQUIMOD_0.5H_BMDC_UP | 190 | 46 | 17377 | 2626 |
DDX47,ZCCHC9,THOC1,ANXA6,FAM207A,IVNS1ABP,COPE,TMEM97,TIA1,SMC6,EIF2AK4,HCFC1R1,SLC20A1,PNO1,CHKA,CSDE1,CDK5,CAPN2,DECR1,KLF16,NDUFB4,MCM5,CS,AQR,ST8SIA2,MCMBP,GCC1,POC5,SPTAN1,BICD2,MCM2,PTTG1IP,FOXRED1,RPL36,CHCHD3,EIF3K,HHEX,SURF4,SNAP23,RBMS1,GPI,NDE1,RUFY3,B4GALT3,ADNP2,CCDC137 |
| 6.335e-04 | -7.36 | GSE22935_WT_VS_MYD88_KO_MACROPHAGE_12H_MBOVIS_BCG_STIM_DN | MSigDB lists | GSE22935_WT_VS_MYD88_KO_MACROPHAGE_12H_MBOVIS_BCG_STIM_DN | 190 | 46 | 17377 | 2626 |
MCM10,TRIP10,C19orf25,UBE2Z,CHIC2,NUF2,KIF2C,LYN,FBRS,CRKL,CSDE1,VASP,CLIC4,GLIS2,SNX18,SLC44A1,PTPN11,MECR,ARHGEF2,FOXN2,AFF1,PTGES3,ABI1,MORC3,CDC37,ADAM17,PSRC1,TNFAIP3,RAD51AP1,WDR1,MYBL2,FAM133B,DNAJA1,PKMYT1,OGFR,ISG15,FAS,PPP2CA,SEPT1,SMAD2,CCDC86,SURF4,TAB2,HMGB2,ACTB,RNF14 |
| 6.335e-04 | -7.36 | GSE2770_IL12_AND_TGFB_ACT_VS_ACT_CD4_TCELL_6H_DN | MSigDB lists | GSE2770_IL12_AND_TGFB_ACT_VS_ACT_CD4_TCELL_6H_DN | 190 | 46 | 17377 | 2626 |
ZNF207,CYTIP,KARS,HNRNPAB,GNE,GADD45G,UCK2,CSNK2A1,NIPA2,NANS,SLC25A44,PNO1,CFLAR,PRNP,PA2G4,ATP2A2,SAR1A,IMPAD1,AHSA1,ZDHHC13,RPN2,PTGES3,UBE3C,TFG,PDIA6,SGCB,STRAP,RNLS,BAK1,STAU1,TRAFD1,TMEM39A,KIAA0040,PGS1,NARF,TOMM40,GAR1,MAT2A,MAN2A2,NUCB1,MTHFD2,SNRPG,LRP8,B4GALT2,BYSL,FUBP1 |
| 6.347e-04 | -7.36 | GO_REGULATION_OF_INTRACELLULAR_TRANSPORT | MSigDB lists | GO_REGULATION_OF_INTRACELLULAR_TRANSPORT | 589 | 118 | 17377 | 2626 |
ZBED3,CYLD,TXN,CHERP,RAB11B,NF1,ZDHHC8,DYNLL1,ANK3,STARD7,PLAGL2,PRKACA,MAPK14,LYN,RBM4,PARK7,BCAP31,CALM2,CDK5,RAB21,RAP1A,MDM2,SP100,ATP2A2,CDC42,SIVA1,PIK3R2,SRI,PARL,NUP153,CORO1A,MAVS,CYB5R1,TP53BP2,F2R,OGG1,ZC3H3,HTRA2,PLK3,BAK1,AKT2,GOPC,PSMB7,EZR,BRCA1,NUTF2,SOX4,EDEM2,SLC25A5,TRIM28,USP36,IWS1,TONSL,PSMD8,AXIN1,OGT,ZNF268,MAPK1,SMAD4,OAZ1,AAAS,SVIP,DDX58,UBE2D3,PPP1R12A,RAB23,NUP54,CIB1,PPP3CB,ARF1,FKBP1A,NUS1,HUWE1,RIMS3,PTPN11,AXIN2,FAM89B,GTSE1,ATG13,MDFIC,BCL2,MYO5A,PDPK1,TGFB1,GCC2,PPP3CA,RHOA,KAT2A,NUDT4,ACSL3,RANGAP1,GOSR1,MAP2K2,SH3GLB1,PRDX1,MAPK3,AKAP1,NUCB1,KEAP1,KPNA1,PCM1,CSK,OAZ2,STX18,TFDP1,PML,E2F1,PPP3R1,NUP62,PKD2,YWHAZ,RUFY3,PARP10,YWHAH,RNF139,CDKN2A,FAF1,SNAPIN |
| 6.353e-04 | -7.36 | positive regulation of viral transcription | biological process | GO:0050434 | 41 | 15 | 17256 | 2622 |
TFAP4,CTDP1,POLR2I,POLR2J,POLR2G,POLR2L,POLR2K,ZNF639,DHX9,POLR2D,SMARCA4,MDFIC,CHD1,POLR2A,GTF2F1 |
| 6.353e-04 | -7.36 | regulation of spindle organization | biological process | GO:0090224 | 41 | 15 | 17256 | 2622 |
PLK1,CHMP2A,PSRC1,SMC3,PDCD6IP,RAE1,TPX2,NUP62,CHMP4B,CHMP2B,BORA,TACC3,SPAG5,DCTN1,HSPA1B |
| 6.355e-04 | -7.36 | Psmb5 (proteasome (prosome, macropain) subunit, beta type 5) | protein interactions | 19173 | 63 | 21 | 17029 | 2761 |
TOMM20,SCAMP3,RAC1,PSMB7,PSMA1,CUL1,PSMG1,BCLAF1,B4GALT4,PRKACA,PSMB3,MEAF6,PSMC4,PSMD2,PSMA6,PSMD1,TIMM23,PSMD3,FBXO7,NCLN,PSMC1 |
| 6.355e-04 | -7.36 | FUBP3 (far upstream element binding protein 3) | protein interactions | 8939 | 63 | 21 | 17029 | 2761 |
RHOA,CSRP1,NQO1,SUZ12,ATXN1,MCM2,SEC16A,PCBP1,MATR3,APP,ARF4,ISG15,NDUFS4,RPA1,CAND1,RPA2,KHSRP,NUP62,TARDBP,PCBP2,FUBP1 |
| 6.355e-04 | -7.36 | LTN1 (listerin E3 ubiquitin protein ligase 1) | protein interactions | 26046 | 63 | 21 | 17029 | 2761 |
CCDC93,CTDP1,SEC61B,CLSPN,TAP1,RPL6,TGOLN2,CHMP2B,MAPK3,SSR1,RPA1,KIF2A,TET3,HLA-B,PLD3,KIF18B,SP100,MBOAT1,XRCC3,ILKAP,PRPF19 |
| 6.355e-04 | -7.36 | PNKP (polynucleotide kinase 3'-phosphatase) | protein interactions | 11284 | 63 | 21 | 17029 | 2761 |
ATXN3,NASP,PRKDC,DNAAF5,SLC25A12,DDX20,CDK11B,FOXO3,APP,LMNA,RPA1,XRCC5,SUPT16H,RPA2,TRIM26,ZNF639,MCM5,TCOF1,GEMIN4,XRCC4,SSRP1 |
| 6.360e-04 | -7.36 | pituitary-adenoma-FSH-LH | COSMIC cancer mutations | pituitary-adenoma-FSH-LH | 12 | 7 | 17385 | 2587 |
GNAS,KRAS,RB1,NRAS,MEN1,HRAS,AXIN1 |
| 6.360e-04 | -7.36 | cervix-carcinoma-mixed_adenosquamous_carcinoma | COSMIC cancer mutations | cervix-carcinoma-mixed_adenosquamous_carcinoma | 12 | 7 | 17385 | 2587 |
STK11,KRAS,FGFR3,NRAS,PTEN,HRAS,CDKN2A |
| 6.360e-04 | -7.36 | extraadrenal | COSMIC cancer mutations | extraadrenal | 12 | 7 | 17385 | 2587 |
GNAS,CDKN2C,KRAS,MAX,MEN1,PTEN,VHL |
| 6.360e-04 | -7.36 | FSH-LH | COSMIC cancer mutations | FSH-LH | 12 | 7 | 17385 | 2587 |
GNAS,RB1,KRAS,NRAS,MEN1,HRAS,AXIN1 |
| 6.363e-04 | -7.36 | LINDGREN_BLADDER_CANCER_CLUSTER_2A_DN | MSigDB lists | LINDGREN_BLADDER_CANCER_CLUSTER_2A_DN | 129 | 34 | 17377 | 2626 |
RAB14,C9orf78,UBE2E2,TSC22D3,TMX4,HABP4,TGOLN2,DUSP22,DNAJB9,RAB21,CLIC4,NEK6,IARS,CCDC50,DPYSL2,RAD23B,PPP6C,FBXW2,ANXA5,SGCB,MYO5A,TGFB1,PSMB7,ITM2A,ARMC8,ZFAND5,RHOB,KIF2A,DNAJC10,SERF2,NFIL3,RNF38,PRPF4,PTPDC1 |
| 6.363e-04 | -7.36 | GO_GENE_SILENCING_BY_RNA | MSigDB lists | GO_GENE_SILENCING_BY_RNA | 129 | 34 | 17377 | 2626 |
NUP188,POLR2K,RAE1,NUP54,SND1,SRRT,METTL3,RBM4,NUP205,CNOT3,HNRNPA2B1,NUP210,NUP107,NUP153,CNOT6L,STAT3,PABPC1,NUP85,SEH1L,POLR2I,POLR2L,POLR2G,POLR2D,NUP155,PRKRA,POLR2A,SMAD2,POLR2J,DGCR8,NUP62,CNOT6,H3F3A,SMAD1,AAAS |
| 6.370e-04 | -7.36 | PHC2 (polyhomeotic homolog 2) | protein interactions | 1912 | 89 | 27 | 17029 | 2761 |
PLK1,TRIM41,POLR2L,NCK1,MAPKAPK3,PRKAA1,MCM2,PCGF1,MAPK14,PPP1R16B,BSDC1,PHC2,CRKL,SYNCRIP,SIAH1,L3MBTL3,MFAP1,C1orf109,MAPK6,KBTBD7,AP1M1,AEN,SPATC1L,CBX4,HDAC2,BYSL,ZBTB24 |
| 6.370e-04 | -7.36 | UBQLN2 (ubiquilin 2) | protein interactions | 29978 | 89 | 27 | 17029 | 2761 |
UBQLN4,EPN1,ADSL,DNAJB1,UBQLN2,PRKACA,STAM,NPLOC4,HSPA1B,RAD23A,ZMYM3,C12orf10,HERC3,RPA2,RPN1,TPD52L2,PSMA6,SNAP23,RAD23B,WDR4,TARDBP,ZRANB2,IGBP1,SMURF1,PSMC1,SSSCA1,USP34 |
| 6.370e-04 | -7.36 | CLINT1 (clathrin interactor 1) | protein interactions | 9685 | 89 | 27 | 17029 | 2761 |
NCK1,GGA1,DYNLL1,CUL3,TMEM216,MYH9,AURKB,CAPZA2,AP1B1,GGA2,ANLN,SEC16A,MAP1LC3B,REPS1,PICALM,SMAP2,RPA1,RPA2,CYHR1,ODF2,MYO18A,GTSE1,AP2B1,MBOAT1,CLTB,TFG,CDC5L |
| 6.370e-04 | -7.36 | COPS7A (COP9 signalosome subunit 7A) | protein interactions | 50813 | 89 | 27 | 17029 | 2761 |
COPS8,MAPRE1,RBX1,DCAF8,RAF1,TOR1AIP1,CUL3,KCTD20,CUL1,CSNK2A1,NUF2,PMF1,CDC23,BTBD1,DTL,EIF2S2,DDA1,FBXO7,DCAF11,PQBP1,ARHGEF2,COPS7B,COPS6,BTBD10,TNRC18,UBE2M,DDB1 |
| 6.377e-04 | -7.36 | GO_MITOCHONDRIAL_ELECTRON_TRANSPORT_CYTOCHROME_C_TO_OXYGEN | MSigDB lists | GO_MITOCHONDRIAL_ELECTRON_TRANSPORT_CYTOCHROME_C_TO_OXYGEN | 15 | 8 | 17377 | 2626 |
COX5A,NDUFA4,COX15,CYCS,COX5B,COX4I1,COX7A2L,COX8A |
| 6.377e-04 | -7.36 | GO_DNA_REPLICATION_FACTOR_A_COMPLEX | MSigDB lists | GO_DNA_REPLICATION_FACTOR_A_COMPLEX | 15 | 8 | 17377 | 2626 |
RPA2,TONSL,HELB,XPA,PURA,PRPF19,CDC5L,RPA1 |
| 6.377e-04 | -7.36 | MODULE_116 | MSigDB lists | MODULE_116 | 15 | 8 | 17377 | 2626 |
ATP6V0A1,ATP6V0C,ATP6V0B,ATP6V1D,ATP6V1B2,ATP6V0D1,ATP6V0E1,ATP6V1G1 |
| 6.377e-04 | -7.36 | REACTOME_SHC_MEDIATED_SIGNALLING | MSigDB lists | REACTOME_SHC_MEDIATED_SIGNALLING | 15 | 8 | 17377 | 2626 |
KRAS,NRAS,SHC1,MAPK1,HRAS,RAF1,MAP2K2,MAPK3 |
| 6.377e-04 | -7.36 | REACTOME_SIGNALLING_TO_P38_VIA_RIT_AND_RIN | MSigDB lists | REACTOME_SIGNALLING_TO_P38_VIA_RIT_AND_RIN | 15 | 8 | 17377 | 2626 |
KRAS,RIT1,NRAS,MAPK1,MAP2K2,HRAS,RAF1,MAPK3 |
| 6.377e-04 | -7.36 | REACTOME_SHC1_EVENTS_IN_EGFR_SIGNALING | MSigDB lists | REACTOME_SHC1_EVENTS_IN_EGFR_SIGNALING | 15 | 8 | 17377 | 2626 |
KRAS,NRAS,SHC1,MAPK1,MAP2K2,HRAS,RAF1,MAPK3 |
| 6.379e-04 | -7.36 | BIDUS_METASTASIS_DN | MSigDB lists | BIDUS_METASTASIS_DN | 144 | 37 | 17377 | 2626 |
GMFG,MUM1,B4GALT1,PTP4A3,SECISBP2,IRF3,MAN2B1,EIF1B,PRPF18,NEIL2,SLC25A37,CFLAR,GTF2F1,PDK2,CORO1A,MARCH2,TTC17,MVP,FAM3A,PHF20L1,HEMK1,DDX24,SELPLG,CIRBP,STK17B,BRMS1,BRWD1,SIL1,STK11,RGL1,RNASEL,CLU,ZNF45,TFDP2,PARP10,CHPF2,N4BP2L2 |
| 6.395e-04 | -7.35 | GSE6259_33D1_POS_DC_VS_BCELL_DN | MSigDB lists | GSE6259_33D1_POS_DC_VS_BCELL_DN | 139 | 36 | 17377 | 2626 |
C9orf78,H2AFZ,RPLP2,TRIM11,RPL15,NCAPG,FARSA,VASP,SH3BP1,CS,TIMELESS,CORO1A,ALDH18A1,TALDO1,GTF2H2,MTPN,GM2A,PDCL3,ITM2A,LRRC1,GSTCD,ANLN,KIF11,H2AFV,HAUS8,SERF2,BIRC5,RPLP1,LY75,PPP1R11,SLAIN1,AKNA,LTA4H,RPS26,ATP6V0E1,IPO4 |
| 6.401e-04 | -7.35 | intrinsic apoptotic signaling pathway by p53 class mediator | biological process | GO:0072332 | 58 | 19 | 17256 | 2622 |
PGAP2,TMEM109,CDIP1,TOPORS,JMY,PDK2,HINT1,HIPK2,E2F1,PML,MSH2,AEN,DDX5,STK11,CHEK2,TP53BP2,E2F2,ZMAT3,IFI16 |
| 6.401e-04 | -7.35 | transport of virus | biological process | GO:0046794 | 58 | 19 | 17256 | 2622 |
NDC1,NUP188,RAE1,NUP54,NUP155,NMT2,NUP205,NUP210,KPNA1,KPNA4,RPS27A,NUP107,NUP62,KPNA2,NUP153,NUP58,NUP85,AAAS,SEH1L |
| 6.413e-04 | -7.35 | NOS2 (nitric oxide synthase 2) | protein interactions | 4843 | 149 | 40 | 17029 | 2761 |
HSPH1,RAC1,SNRPD3,CDIPT,PCBP1,PSMD2,PSMA6,ATP2A2,HUWE1,UCHL5,PPP6C,YBX1,PTGES3,STRAP,PCBP2,TIMM50,CCT2,SNRPB,PRKDC,PARP4,HNRNPF,PSMB7,PSMA1,PLEC,DNAJA1,SLC25A5,CCT8,CLNS1A,XRCC5,PSMC4,ALDH3B1,NAP1L1,PEX5,HSPA4,PSMD3,PSMD8,ACTB,YWHAZ,RUVBL2,PSMC1 |
| 6.427e-04 | -7.35 | NFKB1 (nuclear factor kappa B subunit 1) | protein interactions | 4790 | 173 | 45 | 17029 | 2761 |
UBE2D3,COMMD10,NCOR2,TXN,TSC22D3,NKRF,COMMD5,PRKACA,CNOT11,COMMD6,ETS1,COMMD8,COPB2,CFLAR,SPPL2A,PPME1,CNOT6L,STAT3,MTPN,CARM1,PHF10,TNFAIP3,BIRC3,CUL3,BRCA1,MEN1,COMMD4,POLR2A,BRMS1,PLD3,HSPA4,TAB2,STAT6,PML,E2F1,CNOT6,CLU,NCOA1,RUVBL2,COPS6,YY1,XRCC4,PDCD11,SMAD4,HDAC2 |
| 6.478e-04 | -7.34 | Glycosphingolipid metabolism | REACTOME pathways | R-HSA-1660662 | 46 | 17 | 10287 | 1696 |
GALC,HEXB,CERK,GBA,ASAH1,SUMF1,SUMF2,ESYT1,ARSK,NEU1,CTSA,GLTP,PSAP,SMPD4,HEXA,GM2A,ESYT2 |
| 6.483e-04 | -7.34 | GSE2770_UNTREATED_VS_IL12_TREATED_ACT_CD4_TCELL_6H_DN | MSigDB lists | GSE2770_UNTREATED_VS_IL12_TREATED_ACT_CD4_TCELL_6H_DN | 185 | 45 | 17377 | 2626 |
CTDP1,PKP4,CORO7,ST13,TMBIM4,PHB2,TAP1,CHIC2,ZADH2,SYNRG,GLRX3,CPNE3,ASAP2,MLX,STRBP,GOT2,CLCN6,AFF1,TAF5L,TAP2,OSTC,PPA1,CTDSP2,PACS2,RNF169,TXNL1,GTF3C6,CYTH1,NET1,RPS10,PRKRA,TRIM28,IRF5,PI4K2A,PWWP2B,ORMDL2,PSMD3,H2AFX,SIL1,SCARB1,GALNT10,SLC22A23,MYO9A,WDR91,ESYT2 |
| 6.483e-04 | -7.34 | GSE2770_UNTREATED_VS_TGFB_AND_IL4_TREATED_ACT_CD4_TCELL_4H_UP | MSigDB lists | GSE2770_UNTREATED_VS_TGFB_AND_IL4_TREATED_ACT_CD4_TCELL_4H_UP | 185 | 45 | 17377 | 2626 |
IER2,HECA,DNAJC5,CDS2,TRIM11,RRAGC,KLF13,MYNN,AKT1S1,TMED3,MAP1LC3B,REEP5,RAPGEF6,FAM8A1,FLAD1,RNFT1,ETV6,PPCDC,SRI,SLC35C2,DRAM2,PDLIM2,ZNF524,CYTH1,PBXIP1,BAZ2A,COQ10B,JTB,FBXO9,MAP4K3,PLEC,AZI2,NSA2,TMEM127,TBC1D17,SNAP29,HIPK2,KLHL15,CAPN7,DUSP11,FBXL3,IGBP1,PDLIM5,NRBP1,PDCD4 |
| 6.483e-04 | -7.34 | GSE45365_HEALTHY_VS_MCMV_INFECTION_BCELL_IFNAR_KO_UP | MSigDB lists | GSE45365_HEALTHY_VS_MCMV_INFECTION_BCELL_IFNAR_KO_UP | 185 | 45 | 17377 | 2626 |
MAX,PKP4,TRIP12,HJURP,TMBIM4,MDH2,ACTR3,BABAM1,TPX2,ENSA,CYCS,KIF2C,METTL3,ANKIB1,PSMD1,RALB,KIF14,POLR1B,PIKFYVE,EEF1D,UBE2QL1,GCC2,FOXK1,TLK1,POLR2D,GMFB,CUL3,PSMB7,RPL6,EMP3,EIF2AK1,FAM133B,SEPT7,ANLN,KDM3A,RFC2,EIF3G,BIRC5,PSMD8,DBI,STAT1,PML,CNOT6,MZT2B,PSMC1 |
| 6.483e-04 | -7.34 | GSE10239_KLRG1INT_VS_KLRG1HIGH_EFF_CD8_TCELL_UP | MSigDB lists | GSE10239_KLRG1INT_VS_KLRG1HIGH_EFF_CD8_TCELL_UP | 185 | 45 | 17377 | 2626 |
KARS,TOMM20,DDX47,NDUFAF2,RAE1,HMGXB3,EIF3D,ADCK5,GGA2,C19orf48,PABPC4,NUDT19,ZNF428,TMEM69,NEK6,EIF4A3,SIVA1,ATIC,PIN1,MRPL11,RBM15B,UBE2QL1,LDHB,ANKRD37,TMEM216,POLR2D,VDAC1,DDX39A,TXNL4A,TRIM28,ALKBH6,STOML2,RPL36,TPD52L2,TIMM13,HSPBP1,PRDX3,CHCHD1,SIAH2,SLC25A19,DTD1,SPRYD4,PDSS2,SLC25A33,CDKN2A |
| 6.483e-04 | -7.34 | GSE9037_WT_VS_IRAK4_KO_BMDM_UP | MSigDB lists | GSE9037_WT_VS_IRAK4_KO_BMDM_UP | 185 | 45 | 17377 | 2626 |
TBC1D12,MMACHC,PDAP1,IKBIP,ETS1,RCOR3,CDC73,LIN9,PRKD3,RRN3,KLHL20,NT5DC1,IL6ST,BANF1,TANK,FNIP2,ATG13,RP2,F2R,PHKG2,CDK12,ZNF583,LUC7L2,TNFAIP3,KLF10,LONRF3,CREG1,C16orf72,METTL5,UTP15,CIRBP,AZI2,VDAC1,KLF6,MAT2A,SH3BP5,DUS3L,STT3A,CERS6,CHD3,TULP3,TBPL1,OSGEPL1,NR2F2,ARHGAP23 |
| 6.483e-04 | -7.34 | GSE15930_STIM_VS_STIM_AND_IFNAB_24H_CD8_T_CELL_UP | MSigDB lists | GSE15930_STIM_VS_STIM_AND_IFNAB_24H_CD8_T_CELL_UP | 185 | 45 | 17377 | 2626 |
MIF,KIF3B,KLHL21,DNAJB2,COPE,ASAH1,DNAJB1,ARF1,ATP6V1B2,FZD6,MAT2B,SEC11A,RAB4A,BUD31,PPP6C,BRD7,PDCD2,CNN2,NFU1,ATF2,NCOA2,PREB,GABPA,EMP3,DNAJC9,GALK2,DNAJA1,DCUN1D5,MEF2D,NUTF2,ANLN,MATR3,ANKRD10,ANKZF1,MKNK1,POLR2J,AXIN1,LUC7L3,OGT,LY75,HMGB2,RBBP4,CHPT1,MRPL13,PGAM1 |
| 6.483e-04 | -7.34 | GSE23505_IL6_IL1_VS_IL6_IL1_IL23_TREATED_CD4_TCELL_DN | MSigDB lists | GSE23505_IL6_IL1_VS_IL6_IL1_IL23_TREATED_CD4_TCELL_DN | 185 | 45 | 17377 | 2626 |
TCF12,UBL3,ZBTB10,MZT1,B4GALT5,TRMT6,RRAGC,SLC20A1,ABHD16A,GNS,IRF4,CLIC4,AHCTF1,DUS4L,RBM34,ZNHIT6,EXOSC1,AFF1,PIK3IP1,CNOT6L,LDLRAD3,RYBP,PLK3,POU2AF1,SRSF11,IFRD1,BIRC3,TAOK1,ZBED5,CAMSAP1,SLC17A5,MAT2A,SH3BP5,CDC16,BRWD1,RBM47,TXNDC16,DUSP3,HNRNPR,GRIPAP1,OSBPL8,MAFK,BEND3,DCAF5,PURA |
| 6.483e-04 | -7.34 | GSE15330_LYMPHOID_MULTIPOTENT_VS_GRANULOCYTE_MONOCYTE_PROGENITOR_IKAROS_KO_UP | MSigDB lists | GSE15330_LYMPHOID_MULTIPOTENT_VS_GRANULOCYTE_MONOCYTE_PROGENITOR_IKAROS_KO_UP | 185 | 45 | 17377 | 2626 |
IMMT,ABCA3,NUP188,KRBA1,TM9SF4,SHPRH,MCCC1,NOTCH2,RGS2,IFT27,PARN,FOXO3,SDHA,PIP4K2A,MDM2,SMC3,DUT,PPCDC,BCAP29,APOOL,MRPL21,RNF135,NUP85,NCOA2,SRPK2,ACSL5,RPAP3,PPIF,RPRD1A,MAPRE2,NASP,FOXK1,POLR2G,POLK,IDH3A,TUBGCP5,ILF3,LACTB,MRPL16,MRPS14,SUGP1,STAT6,NAA20,TRAF5,MAPK1 |
| 6.483e-04 | -7.34 | GSE17721_POLYIC_VS_PAM3CSK4_4H_BMDC_UP | MSigDB lists | GSE17721_POLYIC_VS_PAM3CSK4_4H_BMDC_UP | 185 | 45 | 17377 | 2626 |
EWSR1,MCM10,GPBP1L1,MRPL39,TSC22D3,TOR3A,MRPS26,SUMF1,RACGAP1,PXMP2,GYG1,ATP6V1B2,SLC12A9,PRNP,PTPN2,FANCL,USF1,APLP2,SH3BP1,ATG3,FAM89B,NUP153,APOOL,PLCL2,TFG,SRPK2,KDM3B,NEK7,RPL38,TOPORS,KLF6,HAUS8,PI4K2A,DNAJC10,EIF4ENIF1,ATP6V1D,TXNDC16,ELMO1,SNAP29,CDCA5,CHMP4B,ACADM,TCOF1,CSNK1D,ADAM23 |
| 6.483e-04 | -7.34 | GSE3039_B2_VS_B1_BCELL_DN | MSigDB lists | GSE3039_B2_VS_B1_BCELL_DN | 185 | 45 | 17377 | 2626 |
SUCLG1,CLSPN,HMGXB3,CDCA8,KIF2C,CD320,CNOT3,COQ4,GOT2,TAGLN2,CENPM,PPA1,IMPA2,UBE2QL1,RBM15B,METTL1,MLEC,RHOA,PSRC1,KAT2A,RNASEH2C,RAB7A,LDHA,UBE2V1,ARHGDIB,FANCE,SNRPA,ASF1B,CCDC127,AKAP1,SLC19A1,PWWP2B,POLE,COX8A,H2AFX,AEN,KPNA2,SSNA1,SMPD4,GPI,CENPT,PPP6R2,CABLES1,HRAS,FAM72A |
| 6.483e-04 | -7.34 | GSE3039_CD4_TCELL_VS_NKT_CELL_DN | MSigDB lists | GSE3039_CD4_TCELL_VS_NKT_CELL_DN | 185 | 45 | 17377 | 2626 |
GMFG,TRAF7,GADD45G,WDTC1,MON1B,AGPAT1,USP39,COMMD5,NCAPG,IFT27,TUBGCP2,PA2G4,TIMELESS,ORAI1,PRADC1,SPTSSA,RPRD1B,PPP6R1,S100A6,SPSB3,SMC4,IFRD1,MND1,MAN1B1,LDHA,PEF1,PATL1,TFEB,GPR137,POLE,DSN1,GPS2,PSMD3,E2F4,DBI,ANP32E,SSNA1,DMWD,CENPT,WDR62,TAF6,MZT2B,C7orf26,AAAS,ESYT2 |
| 6.483e-04 | -7.34 | GSE16385_IFNG_TNF_VS_UNSTIM_MACROPHAGE_ROSIGLITAZONE_TREATED_DN | MSigDB lists | GSE16385_IFNG_TNF_VS_UNSTIM_MACROPHAGE_ROSIGLITAZONE_TREATED_DN | 185 | 45 | 17377 | 2626 |
DDX58,PARP12,KIAA0232,PCSK7,JMJD6,CDK13,TGOLN2,EZH1,MBD4,CAPN2,IRF4,ADD3,WDR44,IL6ST,ZNF200,BCL2,CYB5R1,MVP,VPS13B,MOB4,ATP13A1,COQ10B,LRBA,TYW1,MTMR6,KRAS,PRPF3,STX16,PDE3B,POLG2,GOSR1,CDK11A,BTBD1,RBM38,RAD54B,MAN2A2,PPP2R5A,WDR59,STAT1,CEBPG,CAB39,KLHDC4,GALNT10,TOB1,ZBTB24 |
| 6.483e-04 | -7.34 | GSE17721_LPS_VS_POLYIC_1H_BMDC_DN | MSigDB lists | GSE17721_LPS_VS_POLYIC_1H_BMDC_DN | 185 | 45 | 17377 | 2626 |
LUZP1,UBN1,TCF3,GADD45G,CTCF,GGA2,DAZAP2,FAM8A1,BIRC2,CRKL,ADD3,FIZ1,ZNF746,ORAI1,AQR,CPSF4,SENP1,KDELR1,PREB,ABCC1,HP1BP3,KDM3B,TRIM8,PIGT,TAOK1,SREK1,BMS1,SOX4,PSMB9,LUC7L,DHX57,NECAP2,UBTF,DNAJC10,LUC7L3,OAZ2,ARRDC1,CANT1,CLU,FAU,YWHAH,PFKP,HDAC2,ANXA11,PDCD4 |
| 6.520e-04 | -7.34 | regulation of carbohydrate catabolic process | biological process | GO:0043470 | 76 | 23 | 17256 | 2622 |
NDC1,NUP188,RAE1,PRKAA1,NUP54,PFKFB3,NUP155,NUP205,PPP1R3B,NUP210,TIGAR,NUP107,OGT,NUP62,NUP153,ECD,PGAM1,STAT3,NUP58,PHKG2,NUP85,AAAS,SEH1L |
| 6.529e-04 | -7.33 | REACTOME_CDT1_ASSOCIATION_WITH_THE_CDC6_ORC_ORIGIN_COMPLEX | MSigDB lists | REACTOME_CDT1_ASSOCIATION_WITH_THE_CDC6_ORC_ORIGIN_COMPLEX | 54 | 18 | 17377 | 2626 |
PSMD2,PSMD1,PSMA6,PSMA8,RPS27A,PSMD8,PSMD3,CDT1,PSMB7,PSMA1,CDC6,ORC1,ORC3,PSMB9,PSMD9,PSMC1,PSMB3,PSMC4 |
| 6.545e-04 | -7.33 | HEXA (hexosaminidase subunit alpha) | protein interactions | 3073 | 35 | 14 | 17029 | 2761 |
C9orf78,PCNA,PDCD10,SYNCRIP,HEXB,H2AFX,EZR,AHCY,USP22,H2AFV,KTN1,GM2A,TERF2,RAD23A |
| 6.545e-04 | -7.33 | PRRC2B (proline rich coiled-coil 2B) | protein interactions | 84726 | 35 | 14 | 17029 | 2761 |
IRF4,UNK,EIF3L,KLHL15,CERK,ATXN1,USP11,SEC16A,EYA2,PICALM,APP,EIF3H,ZER1,SRPK2 |
| 6.545e-04 | -7.33 | LIN28B (lin-28 homolog B) | protein interactions | 389421 | 35 | 14 | 17029 | 2761 |
NOL12,NSA2,NIFK,EIF4A3,RBM34,RPL6,RPL8,SNRPG,FBL,PURA,SNRPA,ZC3HAV1,USP36,KRR1 |
| 6.545e-04 | -7.33 | CHAF1B (chromatin assembly factor 1 subunit B) | protein interactions | 8208 | 35 | 14 | 17029 | 2761 |
PCNA,BANF1,SUMO2,UHRF2,NFATC2,RBPJ,CNOT6L,RBBP4,CDK2,APP,SMAD4,ASF1B,CHAF1A,CBX3 |
| 6.545e-04 | -7.33 | LDHAL6B (lactate dehydrogenase A like 6B) | protein interactions | 92483 | 35 | 14 | 17029 | 2761 |
GNS,BCCIP,WDR1,ARF5,SOCS4,TKT,APPL2,LDHA,MDH1,ARF1,TALDO1,RAB1A,CAPN1,ARF4 |
| 6.547e-04 | -7.33 | GO_NEGATIVE_REGULATION_OF_KINASE_ACTIVITY | MSigDB lists | GO_NEGATIVE_REGULATION_OF_KINASE_ACTIVITY | 243 | 56 | 17377 | 2626 |
FGFR1OP,GMFG,TSC2,NF1,CIB1,AKT1S1,RGS2,DUSP22,PSEN1,LYN,PARK7,PTPN2,TFAP4,CDKN2C,RB1,PTEN,FBXO7,SOCS6,H2AFY,CDKN1B,PIK3IP1,MVP,SOCS5,PDPK1,PLK1,TNFAIP3,NCK1,PRKAR1B,GBA,GMFB,CUL3,LRP5,DNAJA1,MEN1,PRPSAP1,SOCS7,SH3BP5,PPP2CA,HHEX,MBIP,PPP2R5A,DUSP3,CSK,PRDX3,GPS2,CORO1C,STK38,GADD45B,SOCS4,NUP62,DVL1,NR2F2,UBE2C,HIPK3,CDKN2A,PDCD4 |
| 6.553e-04 | -7.33 | response to organonitrogen compound | biological process | GO:0010243 | 889 | 170 | 17256 | 2622 |
MAX,SIRT2,UBQLN2,MAPK14,BIRC2,RNF103,PRNP,EEF2K,CDK5,USF1,RAB8A,RAP1A,PCNA,GOT2,PIK3R2,SRSF4,DNM2,AKR1B1,UPRT,OGG1,DNMT1,CARM1,CDC5L,LARS,KLF10,GABPA,AKT2,GNG7,EZR,CDC6,LRP5,BRCA1,DHX15,HHEX,TMED10,OGT,ITGB1,ATP6V0C,ACTB,PSMC1,C2CD5,ATP6V0E1,HDAC2,SLC25A33,TMUB1,AGTRAP,PRKAA1,LAMTOR3,PSEN1,ARID1B,RHBDD1,NPLOC4,NDUFS4,CFLAR,RNF121,PDXP,EFTUD2,TIMELESS,ATP6V0A2,CYC1,ATP6V0D1,SOCS5,CYFIP1,AACS,ERLIN1,MAN1B1,UBE4B,SRSF5,SYVN1,ADRB2,PKM,APPL1,IRF5,PSMC4,ADSS,DERL1,CAT,EPRS,TSC1,CSK,NSMF,LAMTOR4,RBBP4,ECPAS,RNF139,ATXN3,DNMT3A,TOMM20,UBR2,SLC2A1,WDTC1,RRAGC,BCL2L1,ATP6V1B2,PRKACA,LYN,APP,GNB2,ATP6V0B,PDK2,MDM2,CCNA2,SHC1,ADCY9,CDKN1B,AHCYL1,SPIDR,CFL1,ATP6V1G1,ADCY7,SEC61B,KAT7,BTG2,SLC26A6,ATP6V0A1,ERBIN,EDEM2,SOCS7,ANKZF1,DNAJC10,IDE,SCAP,STAT1,SEL1L,TICAM1,PPP5C,MAPK1,ABCA1,USP13,GCLM,CASP6,SRSF6,UBE4A,SDF2L1,BLM,AP3S1,FOXO3,DNAJB9,PTPN2,CAPN2,HOMER1,PTEN,ARHGEF2,CREB1,STAT3,RNLS,RNF5,MYO5A,TGFB1,PDPK1,PPP1R9B,PPP3CA,RHOA,TNFAIP3,PRKDC,DENND4C,PRKAR1B,LDHA,RANGAP1,KCNQ1,MEN1,PDE3B,FADD,MAPK3,CACNB1,ATP6V1D,PKD2,ATP6V1C1,CD81,CPEB2 |
| 6.581e-04 | -7.33 | LIANG_SILENCED_BY_METHYLATION_DN | MSigDB lists | LIANG_SILENCED_BY_METHYLATION_DN | 9 | 6 | 17377 | 2626 |
HMGB2,CCNA2,MCM2,FOXM1,KIF11,MKI67 |
| 6.581e-04 | -7.33 | KUMAMOTO_RESPONSE_TO_NUTLIN_3A_DN | MSigDB lists | KUMAMOTO_RESPONSE_TO_NUTLIN_3A_DN | 9 | 6 | 17377 | 2626 |
KIFC1,KIF2C,CCNA2,CCNB1,SPAG5,CENPF |
| 6.589e-04 | -7.32 | UBE2L3 (ubiquitin conjugating enzyme E2 L3) | protein interactions | 7332 | 135 | 37 | 17029 | 2761 |
MMACHC,ATXN3,TRIP12,TRAF7,MDH2,UBXN1,XIAP,MAP1LC3B,BIRC2,RNF103,WWP2,HERC3,PSMD2,MDM2,TIGAR,PTEN,HUWE1,RNF19A,UBE3C,AHCYL1,USP34,BIRC3,RBX1,VDAC2,NDUFA7,BRCA1,UBE4B,MCM2,TRIM28,POLR2A,SUGP1,HSPA4,MAPK6,PITPNA,NCOA1,SMURF1,SMAD4 |
| 6.602e-04 | -7.32 | TFRC (transferrin receptor) | protein interactions | 7037 | 76 | 24 | 17029 | 2761 |
COX15,RAB7A,TMEM216,ACAP1,B4GALT1,BRCA1,ADRB2,RAB5B,CDC73,TFRC,LMNA,OPTN,RPA1,RPA2,RAB8A,HGS,MDM2,HUWE1,AHSA1,AP2B1,CLN3,ATF2,POC5,SVIP |
| 6.602e-04 | -7.32 | NDUFA7 (NADH:ubiquinone oxidoreductase subunit A7) | protein interactions | 4701 | 76 | 24 | 17029 | 2761 |
PRKAB1,RAB7A,RPL38,TPX2,OLA1,NDUFA4,RANGAP1,UBE4B,TOMM40,UBE2I,NDUFS7,NDUFS4,SUGP1,STARD9,RAB8A,PIN1,RRBP1,PQBP1,NABP2,RBMS1,UPF2,NDUFS5,DNAJC30,PDLIM5 |
| 6.602e-04 | -7.32 | PGR (progesterone receptor) | protein interactions | 5241 | 76 | 24 | 17029 | 2761 |
NCOR2,PRKDC,CSNK2A1,BRCA1,DNAJA1,ARID1A,PRMT2,XRCC5,RBM23,DAP3,CCNA2,PIAS2,ANP32A,HMGB2,FKBP5,CDC25B,NCOA1,PPP5C,CDK2,MAPK1,STAT3,SMARCE1,NCOA2,SMARCD1 |
| 6.609e-04 | -7.32 | regulation of glycolytic process | biological process | GO:0006110 | 67 | 21 | 17256 | 2622 |
NDC1,NUP188,RAE1,PRKAA1,NUP54,PFKFB3,NUP155,NUP205,NUP210,TIGAR,NUP107,OGT,NUP62,NUP153,ECD,PGAM1,STAT3,NUP58,NUP85,AAAS,SEH1L |
| 6.620e-04 | -7.32 | microtubule end | cellular component | GO:1990752 | 26 | 11 | 18223 | 2701 |
DST,MAPRE2,MAPRE1,KIF18B,ABRAXAS2,ASPM,CAMSAP1,KIF2C,SPAG5,MYO5A,DCTN1 |
| 6.623e-04 | -7.32 | nuclear pore organization | biological process | GO:0006999 | 15 | 8 | 17256 | 2622 |
NDC1,AHCTF1,NUP107,NUP54,NUP153,SEH1L,NUP205,TMEM33 |
| 6.626e-04 | -7.32 | GSE5589_LPS_VS_LPS_AND_IL6_STIM_MACROPHAGE_45MIN_DN | MSigDB lists | GSE5589_LPS_VS_LPS_AND_IL6_STIM_MACROPHAGE_45MIN_DN | 180 | 44 | 17377 | 2626 |
CTU2,CMAS,SCAMP3,DYNLL1,PRKAA1,NKRF,SLC4A2,WRNIP1,KIF5B,CLIC4,UTP18,RIMS3,RAD23B,MECR,TAGLN2,CYC1,NAP1L4,MRPL40,STRAP,UBE2M,EBAG9,PLK3,ELOVL5,ETV3,ANKRD37,AATF,ELL2,SIGMAR1,SNRPB,NSUN2,GTPBP4,TBRG4,PDE3B,GAR1,EIF3G,DHX15,DTWD1,ORMDL2,ACOX1,LTA4H,SMURF1,CCDC59,CAPN1,FUBP1 |
| 6.626e-04 | -7.32 | GSE29617_CTRL_VS_DAY3_TIV_FLU_VACCINE_PBMC_2008_DN | MSigDB lists | GSE29617_CTRL_VS_DAY3_TIV_FLU_VACCINE_PBMC_2008_DN | 180 | 44 | 17377 | 2626 |
WSB2,GLT8D1,NDUFB6,SCOC,SUCLG1,GNPDA1,DYNLL1,UQCR10,CREBL2,PPP3CB,MAPK14,ASXL2,REEP5,COMMD8,BCAP31,FAM192A,PCNA,NDUFB4,EFTUD2,MEA1,FNIP2,HDHD2,RNF5,CFL1,WDR41,GTF3C6,TIMM8B,POLR2G,CSRP1,NEK7,PITPNB,ICMT,MRPS14,PRDX1,PSMB3,ORMDL2,PPA2,MDH1,ACADM,NAA20,ATP6V0E1,HDAC2,TUBB,ZNF146 |
| 6.626e-04 | -7.32 | GSE5589_WT_VS_IL6_KO_LPS_STIM_MACROPHAGE_45MIN_UP | MSigDB lists | GSE5589_WT_VS_IL6_KO_LPS_STIM_MACROPHAGE_45MIN_UP | 180 | 44 | 17377 | 2626 |
ZNF207,RMND5A,HECA,SCOC,SUZ12,RAF1,CDT1,CHCHD2,UBQLN2,GGA2,TCF19,BCAP31,XPR1,FBXO22,EDC3,GNS,MDM2,SMC3,AHCTF1,UBE2Q2,PTEN,KIF14,SUCLG2,YBX1,GTF2H2,ZNF770,MYO5A,LUC7L2,GPX4,SRSF10,FTL,ULK3,TLK1,LDHA,NLN,POLG2,PDE3B,SRSF1,SCARB2,ATP6V1D,VCPIP1,ZMIZ1,CHMP7,OAZ1 |
| 6.626e-04 | -7.32 | GSE5542_IFNA_VS_IFNA_AND_IFNG_TREATED_EPITHELIAL_CELLS_24H_DN | MSigDB lists | GSE5542_IFNA_VS_IFNA_AND_IFNG_TREATED_EPITHELIAL_CELLS_24H_DN | 180 | 44 | 17377 | 2626 |
ZNF496,MRPL9,ABCA3,POC1A,CENPF,TPX2,MRPS26,CDCA3,CDCA8,KIF23,RACGAP1,KIF2C,NCAPG,PITHD1,TTF1,ARF5,ZNF746,CDC25B,CYB5R1,ATP6V0D1,KDELR1,NASP,MKLN1,ASPM,FOPNL,RAB7A,HELB,CDCA2,NUSAP1,MARK2,OPTN,FNTA,SEPT1,TMEM54,KIF18B,QARS,H2AFX,KPNA2,PPP6R3,RPS6KC1,YWHAH,ACSF2,TERF1,SLC25A33 |
| 6.632e-04 | -7.32 | TERF2IP (TERF2 interacting protein) | protein interactions | 54386 | 154 | 41 | 17029 | 2761 |
C9orf78,DNMT3A,PPP1R2,TOR1AIP1,BABAM1,HMGN3,WDR5,TWF2,CPNE3,TERF2IP,TFAP4,SP100,AP2B1,RPAP1,ANXA5,FBL,TALDO1,TERF2,RPP25,NASP,DDX24,HMGN4,RABIF,CHMP2B,MCM2,OGFR,MPG,HAGH,DDX39A,DDX23,XRCC5,HSPA4,PPM1G,PML,FAM122A,MDH1,WIPI2,PPP6R3,TERF1,POT1,ZNF146 |
| 6.651e-04 | -7.32 | TXNL1 (thioredoxin like 1) | protein interactions | 9352 | 59 | 20 | 17029 | 2761 |
USP7,CCT2,UNK,DHX9,RIOX2,PSMA1,LACTB2,KCMF1,USP5,RAD23A,PSMD2,DNAJC10,PSMA6,PSMD1,PSMD3,PSMD8,UCHL5,PDIA6,ECPAS,PSMC1 |
| 6.651e-04 | -7.32 | CHRM4 (cholinergic receptor muscarinic 4) | protein interactions | 1132 | 59 | 20 | 17029 | 2761 |
PIGM,PPP1R15B,ABCC10,DNAAF5,SLC29A1,ATP5F1B,XPO7,NCAPG,STK17B,PDXDC1,TUBGCP2,CIP2A,THADA,CERS6,PDS5B,LPCAT4,TNPO2,KNTC1,ECPAS,PPP6R1 |
| 6.651e-04 | -7.32 | NKAP (NFKB activating protein) | protein interactions | 79576 | 59 | 20 | 17029 | 2761 |
USP7,FTL,RNPS1,DHX8,CSNK2A1,JMJD6,TOPORS,PRPF3,ARMC8,LUC7L,MYEF2,PIP4K2A,DHX15,SYNCRIP,RBM25,PPIG,NKAPD1,LUC7L2,PCBP2,SRPK2 |
| 6.656e-04 | -7.31 | ACTGCAG,MIR-17-3P | MSigDB lists | ACTGCAG,MIR-17-3P | 100 | 28 | 17377 | 2626 |
CYTH1,FGFR1OP,SNX27,MAX,TM9SF4,ARID2,KAT7,CDK2AP2,RAB6A,RHOT1,ARMC8,RAB11A,DHX57,ZFR,CSDE1,PPP2CA,VEZF1,RAB21,INPP5A,MAP4,OGT,CTR9,CNOT6,DDX5,FKBP5,BTF3,PPP6R3,BRWD3 |
| 6.659e-04 | -7.31 | Spermidine and Spermine Biosynthesis | SMPDB pathways | SMP00445 | 6 | 5 | 992 | 167 |
MAT2B,SRM,ODC1,MAT2A,AMD1 |
| 6.707e-04 | -7.31 | GO_ZINC_ION_BINDING | MSigDB lists | GO_ZINC_ION_BINDING | 1091 | 203 | 17377 | 2626 |
RORB,MIB2,PTMS,KDM4A,ADAM10,PHRF1,CXXC1,ZDHHC8,TRIM11,XIAP,DNAJC24,USP39,SIRT2,RUFY1,KCMF1,RBM4,POLR3K,BIRC2,TRIM65,RNF103,SIVA1,MECR,NUP153,TCEA1,MARCH2,RNF26,ZNRD1,DNMT1,TRIM14,RYBP,TRIM8,BAZ2A,RBX1,EHMT1,LNX2,TOPORS,BRCA1,DIDO1,USP22,ZFAND5,ZMYM3,TRIM4,CXXC4,MAN2A2,TRIM47,TIMM13,RAD18,CHD3,LIMK1,PTER,BAZ1B,ADAM9,TRIM52,ZSWIM3,TRAF5,ZNF598,ZMAT3,DDX58,ZCCHC9,EWSR1,ZCCHC8,POLR2K,PHF23,CTCF,MAN2B1,ZNRF3,RLF,NPLOC4,RNF121,LHX8,MEX3C,ZNRF2,RNFT1,PHF14,ZRANB1,CPSF4,RNF135,PIKFYVE,LRSAM1,MORC3,TIMM8B,PHF10,POLR2I,ZNF84,MTA2,ZMYND11,DCTD,SYVN1,SF3A2,ZDHHC3,MTR,MATR3,PHF6,RXRB,PDLIM1,SIAH2,PIAS2,ZDHHC7,YY1,ZNF830,RNF14,PDLIM5,RNF139,RNF114,ZNF207,MBD1,TRIM41,ASH1L,CYLD,TRAF7,UBR2,TCF19,ZADH2,ANKIB1,USP5,PHC2,CYHR1,ZNF75D,MDM2,BRPF3,KDM2A,SIAH1,MTA1,ZCCHC2,AKAP8,INTS12,TTC3,RNF19A,RNF169,RLIM,BIRC3,POLR2L,PGGT1B,KAT7,RNF25,PCGF6,GLO1,KDM1B,TRIM28,TAF2,AMZ2,ZNF282,IDE,TAB2,NSMCE2,UHRF2,RNF38,TRIM32,PDXK,LTA4H,PITRM1,ZC3HC1,ZNF146,ADAM23,USP13,SHPRH,DBF4,BRAP,CBLL1,MYNN,MYO9B,LANCL1,ZNF92,NEIL2,RFWD3,SUV39H2,SEC24C,PRDM4,ZDHHC13,ARHGEF2,LTN1,GTF2H2,FBXL19,S100A6,MICAL3,RNF5,PDLIM2,ZDHHC18,ADAM17,TK1,TNFAIP3,LONRF3,CSRP1,ZMYM5,TOP3A,RFFL,RABIF,PCGF1,ZNF407,ZFR,UPF1,TRIM26,POLE,BIRC5,ZNF330,NEIL3,PML,DTX4,USP20,ZRANB2,ZMIZ1,NR2F2,ZSWIM6 |
| 6.708e-04 | -7.31 | G13 Signaling Pathway | WikiPathways | WP524 | 40 | 15 | 5312 | 837 |
MAP3K4,CALM2,CYFIP1,RHOA,WAS,CDC42,LIMK1,ARHGEF1,RAC1,PIK3R2,ARHGDIB,ROCK1,PIP4K2A,CFL1,RTKN |
| 6.720e-04 | -7.31 | cellular monovalent inorganic cation homeostasis | biological process | GO:0030004 | 114 | 31 | 17256 | 2622 |
KCTD7,CLCN3,PPT1,TM9SF4,RAB7A,GPR89A,SLC26A6,ATP6V0A1,SLC4A2,ATP5F1B,ATP6V1B2,TMEM165,MAPK3,ATP6V0B,ATP6V1D,CLIC4,ATP1A1,ATP6V0A2,BCL2,ATP6V0C,SLC26A2,ATP6V1C1,CLN3,CLN6,MAPK1,ATP6V0D1,ATP6V0E1,GPR89B,SNAPIN,ATP6V1G1,CHP1 |
| 6.734e-04 | -7.30 | CHICAS_RB1_TARGETS_GROWING | MSigDB lists | CHICAS_RB1_TARGETS_GROWING | 222 | 52 | 17377 | 2626 |
TMEM106C,DEPDC1,CASP6,FOXM1,FAM129A,CENPF,TPX2,TMEM97,CDCA8,CHAC2,CCNB1,LMNA,ANKRD28,FANCL,SMC3,CCNA2,SLC1A4,TNFAIP8,PPIG,KIF14,MSH2,TIMELESS,GTSE1,TTC3,CDC25B,RNASEH2A,IMPA2,MSH6,SMC4,GINS1,NASP,ASPM,RAD51AP1,EZR,DNAJC9,NUSAP1,SMC2,MCM2,SUPT16H,DPYSL3,PRIM1,TRAM2,CERS6,CDCA7L,ANP32E,CLU,NR2F2,CCNB2,TSPAN5,CDKN2A,IFI16,SSRP1 |
| 6.748e-04 | -7.30 | Pancreatic cancer | KEGG pathways | ko05212 | 64 | 21 | 7161 | 1149 |
TGFB1,RAF1,AKT2,RAC1,E2F3,KRAS,BCL2L1,MAPK3,RB1,SMAD2,JAK1,CDC42,RALB,PIK3R2,E2F1,STAT1,STAT3,E2F2,MAPK1,SMAD4,CDKN2A |
| 6.748e-04 | -7.30 | Pancreatic cancer | KEGG pathways | hsa05212 | 64 | 21 | 7161 | 1149 |
TGFB1,RAF1,AKT2,RAC1,E2F3,KRAS,BCL2L1,MAPK3,RB1,SMAD2,JAK1,CDC42,RALB,PIK3R2,E2F1,STAT1,STAT3,E2F2,MAPK1,SMAD4,CDKN2A |
| 6.766e-04 | -7.30 | lysine N-methyltransferase activity | molecular function | GO:0016278 | 62 | 20 | 17224 | 2647 |
ASH1L,KMT2E,CXXC1,SUZ12,EHMT1,WDR82,NSD3,EZH1,WDR5,MEN1,METTL22,KMT2C,DOT1L,IRF4,KMT5C,SUV39H2,SETD3,KMT5A,CAMKMT,KMT2B |
| 6.777e-04 | -7.30 | ATATGCA,MIR-448 | MSigDB lists | ATATGCA,MIR-448 | 201 | 48 | 17377 | 2626 |
RORB,UBL3,ATXN3,ADD1,ADAM10,ARID2,SF3B1,TOR1AIP1,DLGAP4,MED13L,YTHDF3,KLF13,UBE2Z,RAVER2,WRNIP1,HNRNPA2B1,RAB21,KLHL5,IMPAD1,ZCCHC2,DAPK1,BCL2,RNF19A,FAM76B,NCOA2,SOCS5,SRSF10,SP3,ELL2,RAB7A,E2F3,KRAS,TOPORS,BICD2,AZI2,ARMC8,RAB2B,VEZF1,SERTAD2,FBXO28,STT3A,TPP2,ARNTL,SMURF1,DCAF5,TSEN15,PURA,CPEB2 |
| 6.783e-04 | -7.30 | V$ETS1_B | MSigDB lists | V$ETS1_B | 238 | 55 | 17377 | 2626 |
NAT14,ZNF296,TRIM41,LIME1,GGNBP2,CAST,TSC22D3,MAGED1,ACAP1,DLGAP4,KLF13,LYN,FOXO3,GIT2,TMEM161B,CMTM6,SLC25A37,ARL6IP6,SEC24C,ETV6,PTPN11,CORO1A,MTPN,PABPC1,ZNF800,KCNAB2,RLIM,PDLIM2,TTPAL,POU2AF1,PPP1R9B,BAZ2A,MAP4K4,AMD1,E2F3,WDR81,KCNQ1,FOXRED1,LUC7L,ARHGAP15,UBTF,SEPT1,GALNT2,ELMO1,TFE3,TPP2,PML,APPL2,RWDD4,IMPDH1,ST3GAL2,ROCK1,WIPI2,ZMAT3,DEF6 |
| 6.783e-04 | -7.30 | V$NGFIC_01 | MSigDB lists | V$NGFIC_01 | 238 | 55 | 17377 | 2626 |
PTMS,PPP1R12A,SUMO2,IP6K2,FKBP2,AP3S1,APP,WDR48,SAP130,FAM192A,TFAP4,CDKN2C,APLP2,KDM2A,WDR44,SH3BP1,RRBP1,TTC9C,TRA2B,CRY2,PIK3IP1,CNOT6L,GNAI2,PABPC1,DVL2,CGGBP1,LUC7L2,KDM3B,EIF5A,ERF,KAT7,PRPF3,SLC25A5,MATR3,RHOB,HMGN2,CAND1,ADSS,MAN2A2,UBTF,MAP3K4,AHNAK,SYNCRIP,HNRNPR,CORO1C,ERGIC3,PTPN7,FAM122A,PITPNA,MAP3K5,PLOD3,BRWD3,NUDT11,SLC25A39,FAF1 |
| 6.796e-04 | -7.29 | GO_FC_GAMMA_RECEPTOR_SIGNALING_PATHWAY | MSigDB lists | GO_FC_GAMMA_RECEPTOR_SIGNALING_PATHWAY | 72 | 22 | 17377 | 2626 |
WASF2,CYFIP1,NCK1,ACTR3,VAV2,RAC1,WIPF1,NCKAP1,CYFIP2,ARPC1A,LYN,MAPK3,VAV1,WAS,CDC42,ELMO1,ARPC5,LIMK1,PIK3R2,ACTB,MAPK1,ABI1 |
| 6.838e-04 | -7.29 | thiol-dependent ubiquitin-specific protease activity | molecular function | GO:0004843 | 80 | 24 | 17224 | 2647 |
USP7,OTUD5,CYLD,ATXN3,TNFAIP3,USP42,USP10,OTUD3,USP22,USP48,USP21,USP36,USP5,ANKZF1,UCHL5,TANK,USP32,USP20,VCPIP1,JOSD1,USP11,ZRANB1,USP34,USP13 |
| 6.839e-04 | -7.29 | KOKKINAKIS_METHIONINE_DEPRIVATION_48HR_DN | MSigDB lists | KOKKINAKIS_METHIONINE_DEPRIVATION_48HR_DN | 63 | 20 | 17377 | 2626 |
IFRD1,TK1,RRM1,AURKB,MPG,MAPK14,PMVK,RAD54B,EBP,CDK5,GSTK1,CDC42,BIRC5,CEBPG,CANT1,CDC25B,MAP3K14,ATF2,OGG1,DNMT1 |
| 6.839e-04 | -7.29 | YRTCANNRCGC_UNKNOWN | MSigDB lists | YRTCANNRCGC_UNKNOWN | 63 | 20 | 17377 | 2626 |
ELOVL5,MLEC,TACC1,ZBTB37,SLC25A12,PFKFB3,WDR81,PITPNB,KRTCAP2,ZFAND5,LCLAT1,TMEM165,ERC1,NCDN,PPP2CA,LEMD2,PTPN2,SUV39H2,DPYSL2,RNF38 |
| 6.839e-04 | -7.29 | GO_PROTEIN_SERINE_THREONINE_PHOSPHATASE_ACTIVITY | MSigDB lists | GO_PROTEIN_SERINE_THREONINE_PHOSPHATASE_ACTIVITY | 63 | 20 | 17377 | 2626 |
CTDP1,PPP3CA,PPP1R15B,MTMR6,CYCS,PPP3CB,EPM2A,UBLCP1,MTMR3,PTEN,MTMR4,PPM1G,PPA2,PPP3R1,PPP6C,PPP5C,ILKAP,CTDSP2,CAMK2G,TIMM50 |
| 6.848e-04 | -7.29 | regulation of symbiosis, encompassing mutualism through parasitism | biological process | GO:0043903 | 221 | 52 | 17256 | 2622 |
PPIB,CTDP1,CHMP2A,POLR2K,TRIM11,YTHDC2,DHX9,SMARCA4,EIF2AK4,CHD1,GTF2F1,RAD23A,TFAP4,TMEM250,CCNK,SMC3,ZNF639,BANF1,BCL2,MDFIC,TARDBP,MAVS,PABPC1,TRIM14,CFL1,SRPK2,STAU1,POLR2I,TRIM8,POLR2L,POLR2G,RAB7A,PPIE,POLR2D,ILF3,CHMP2B,TRIM28,ISG15,POLR2A,TRIM26,POLR2J,STAT1,PML,CHMP4B,DDX5,RNASEL,TRIM32,VPS4A,PARP10,DDB1,ZC3HAV1,IFI16 |
| 6.859e-04 | -7.28 | BIOCARTA_IL6_PATHWAY | MSigDB lists | BIOCARTA_IL6_PATHWAY | 22 | 10 | 17377 | 2626 |
SHC1,JAK1,IL6ST,RAF1,PTPN11,CSNK2A1,ELK1,STAT3,HRAS,MAPK3 |
| 6.859e-04 | -7.28 | GO_NUCLEAR_TRANSCRIPTIONAL_REPRESSOR_COMPLEX | MSigDB lists | GO_NUCLEAR_TRANSCRIPTIONAL_REPRESSOR_COMPLEX | 22 | 10 | 17377 | 2626 |
ETV3,CHD3,MTA2,APPL2,CSNK2A1,DDX20,RBBP4,MBD3,APPL1,HDAC2 |
| 6.868e-04 | -7.28 | CCT4 (chaperonin containing TCP1 subunit 4) | protein interactions | 10575 | 193 | 49 | 17029 | 2761 |
UNK,CYLD,POC1A,RPS6KA1,ACTR3,WDTC1,CUL1,GNB2,CDC73,SSR1,CDK5,RFWD3,PSMA6,HUWE1,AHSA1,ZNF746,CRY2,RBM3,ATF2,FGFR1OP2,SEH1L,PDCL3,NIPSNAP1,CDC5L,TXNL1,CCT2,STAU1,VHL,DCAF8,CUL3,BRCA1,MCM2,CDK11A,CCT8,RPSA,ISG15,PPP2CA,DCAF11,ACTB,PRPF4,FUS,WDR76,PPP5C,CDK2,IGBP1,ECPAS,SMURF1,CD81,PPP2R2D |
| 6.868e-04 | -7.28 | ribose phosphate biosynthetic process | biological process | GO:0046390 | 164 | 41 | 17256 | 2622 |
GALK1,COX5B,PPCS,UCK2,UCK1,SLC35B2,ATP5F1B,ADPGK,ATP5PF,GART,ATIC,ADCY9,CTPS1,PPCDC,UPRT,ATP6V0A2,SLC26A2,CYC1,ADCY7,AMPD2,TGFB1,GUK1,LDHA,ATP6V0A1,ADSL,OGDH,ATP5MF,PKM,STOML2,ADSS,ATP5MC3,GUCY1B1,PRPS2,IMPDH1,DHTKD1,ACAT1,ATP5F1A,GPI,NIPSNAP2,PGAM1,PFKP |
| 6.873e-04 | -7.28 | ATCATGA,MIR-433 | MSigDB lists | ATCATGA,MIR-433 | 105 | 29 | 17377 | 2626 |
INTS2,PHF20L1,PRPF38B,DNAJC5,TRIP12,CCDC138,MIER1,E2F3,PLAGL2,TIA1,YTHDF3,CYCS,SLC17A5,NMT2,FBXO22,RAP1A,TTC13,BRWD1,HNRNPR,CENPJ,STK38,PARL,CNOT6,SRSF3,ZMIZ1,B4GALT3,CCAR1,TMEM33,HP1BP3 |
| 6.888e-04 | -7.28 | GSE7768_OVA_ALONE_VS_OVA_WITH_MPL_IMMUNIZED_MOUSE_WHOLE_SPLEEN_6H_UP | MSigDB lists | GSE7768_OVA_ALONE_VS_OVA_WITH_MPL_IMMUNIZED_MOUSE_WHOLE_SPLEEN_6H_UP | 170 | 42 | 17377 | 2626 |
FGFR1OP,NAT9,PKP4,TRERF1,UBR2,CDCA8,KLC1,KIF23,OAT,SAFB2,SLC20A1,WRB,NUP205,CDKN2C,SMC3,CCNA2,TBC1D22A,CRAT,JOSD1,TOP1MT,RBM15,MCPH1,SNX8,PLK1,TK1,OXR1,LACTB,CDCA2,ANLN,FANCE,CDCA4,KIF18B,TTLL4,PPM1G,ACLY,UHRF2,FAM83D,USP20,IDH3B,WDR91,REEP4,RAB3IL1 |
| 6.888e-04 | -7.28 | GSE11864_CSF1_IFNG_VS_CSF1_PAM3CYS_IN_MAC_DN | MSigDB lists | GSE11864_CSF1_IFNG_VS_CSF1_PAM3CYS_IN_MAC_DN | 170 | 42 | 17377 | 2626 |
KCTD7,RHOG,PPP1R2,ETS1,LYN,CMTM6,TFRC,PNO1,ABL2,PA2G4,KLHL5,IARS,ATP13A3,CS,DCP1A,TRA2B,TNPO3,JOSD1,DDX31,ATG13,ACSL5,UBQLN4,BTG2,MAP4K4,PFKFB3,ABCF1,IWS1,HGS,FBXO28,BRD2,DGCR8,RBMX,TULP3,FASTK,DTX4,H2AFX,DUSP11,ACTB,RRS1,CHMP7,IPO4,TUBB |
| 6.897e-04 | -7.28 | MARTINEZ_RB1_AND_TP53_TARGETS_DN | MSigDB lists | MARTINEZ_RB1_AND_TP53_TARGETS_DN | 550 | 111 | 17377 | 2626 |
RHOG,NDUFA5,MAX,MRPL39,PIGQ,ANK3,AGPAT1,SMARCA4,SAFB2,APP,MIS12,UBLCP1,SF3B2,PRNP,APLP2,RRN3,STRBP,SIAH1,SIVA1,MTA1,SLC44A1,RAB4A,PPCDC,RPN2,TARDBP,AQR,TECR,ACSL5,PLK1,CCT2,CLCN3,UBQLN4,CELSR2,AATF,KAT7,TAOK1,MKI67,SREK1,MCL1,GLO1,KRTCAP2,TXNL4A,ERC1,CLNS1A,BRD2,TMED10,HIPK2,MAP4,DNAJC17,ATP6V0C,FKBP5,CLU,SNRPG,SMAD1,SMAD4,CCDC137,FUBP1,SEPHS2,PPIB,MIF4GD,ZCCHC9,HJURP,PHB2,PDAP1,SCYL1,NKD2,TIA1,MAN2B1,THRAP3,RAB6A,SLC35B1,PDCD7,FZD6,PIP5K1C,TMCC3,LYAR,NDUFA2,HUWE1,EFTUD2,TNPO3,SLC27A4,MAML1,CPSF4,NDUFA3,LPCAT1,LDHB,TIMMDC1,ZMYND11,RDH10,ZNF574,TUFM,MYBL2,ILF3,RPS24,PLEC,PTTG1IP,SF3A2,NCDN,POLR2A,PSMC4,RDH11,PTPRF,EPRS,GOLGA4,STX18,TFDP1,CEBPG,SRSF3,MAP3K5,RBBP4,HRAS |
| 6.898e-04 | -7.28 | RGS8 (regulator of G protein signaling 8) | protein interactions | 85397 | 4 | 4 | 17029 | 2761 |
ADRB2,GOLGA2,UBR2,NXT2 |
| 6.898e-04 | -7.28 | ATAT1 (alpha tubulin acetyltransferase 1) | protein interactions | 79969 | 4 | 4 | 17029 | 2761 |
CYLD,APP,SSSCA1,SRPK2 |
| 6.898e-04 | -7.28 | HIST1H2AH (histone cluster 1 H2A family member h) | protein interactions | 85235 | 4 | 4 | 17029 | 2761 |
CYLD,MCM2,CDK2,MCM5 |
| 6.898e-04 | -7.28 | NXNL1 (nucleoredoxin like 1) | protein interactions | 115861 | 4 | 4 | 17029 | 2761 |
TERF2IP,POT1,TERF1,TERF2 |
| 6.899e-04 | -7.28 | ARFIP1 (ADP ribosylation factor interacting protein 1) | protein interactions | 27236 | 55 | 19 | 17029 | 2761 |
PPP3CA,TSTA3,AACS,TMEM216,ARFIP2,ARF1,ECH1,ADSS,IDE,PDCD6,GART,HSPBP1,DPYSL2,ARF5,ATP6V1C1,STAT3,LUC7L2,PFKP,CDC5L |
| 6.899e-04 | -7.28 | CDK13 (cyclin dependent kinase 13) | protein interactions | 8621 | 55 | 19 | 17029 | 2761 |
PRPF3,MAPK14,EDRF1,GNB2,CCNK,RB1,CHMP4A,KEAP1,TTC9C,FKBP5,CDK2,ARRB2,TERF1,CDK12,TUBB,SPSB3,TERF2,SRPK2,CDC37 |
| 6.899e-04 | -7.28 | ACTR1B (ARP1 actin related protein 1 homolog B) | protein interactions | 10120 | 55 | 19 | 17029 | 2761 |
CCT2,CYFIP1,TK1,CYLD,SCYL1,DCTN2,CUL3,CAPZA2,APP,KPNA4,KDM2A,GPS2,CHD3,MAPK6,UQCRH,SEH1L,PDCL3,CCAR1,DCTN1 |
| 6.899e-04 | -7.28 | PHLDB3 (pleckstrin homology like domain family B member 3) | protein interactions | 653583 | 55 | 19 | 17029 | 2761 |
CCDC93,SKA3,MAX,RPRD1A,RCOR1,MIER2,NUF2,PSMD9,GIT2,HMG20A,OIP5,MBIP,CDC16,MDM2,GRIPAP1,CENPJ,RABGAP1L,ARNTL,KBTBD7 |
| 6.899e-04 | -7.28 | BRCC3 (BRCA1/BRCA2-containing complex subunit 3) | protein interactions | 79184 | 55 | 19 | 17029 | 2761 |
USP7,MTA2,SUMO2,BABAM1,WDHD1,BRCA1,MCM2,TRIM28,CAND1,SUPT16H,WWP2,BABAM2,DDOST,HUWE1,CCDC6,ABRAXAS2,HNRNPR,DEF6,SMARCD1 |
| 6.899e-04 | -7.28 | ANP32B (acidic nuclear phosphoprotein 32 family member B) | protein interactions | 10541 | 55 | 19 | 17029 | 2761 |
EWSR1,DHPS,ACTR3,CSNK2A1,CDC73,APP,CHAF1A,RPA1,PTPN2,SMAD2,KPNA1,HUWE1,ARPC5,UCHL5,ANP32A,AHCYL1,FAM3A,CD81,SMARCD1 |
| 6.902e-04 | -7.28 | testis-germ_cell_tumour-seminoma | COSMIC cancer mutations | testis-germ_cell_tumour-seminoma | 658 | 128 | 17385 | 2587 |
ABCC10,CSNK2A1,MAPK14,EEF2K,CDK5,ABL2,NEK6,ATG3,PIK3R2,HADHB,SRPK2,USP34,PLK1,PLK3,NRAS,AKT2,VHL,PBK,LRBA,TLK1,AURKB,STK17B,MAP3K4,LIMK1,STK11,RNASEL,CHEK2,PTOV1,LIME1,MUT,DHPS,PRKAA1,TRIO,CDK13,ADCK5,EIF2AK4,PDXDC1,SRRT,JMY,MED10,DAPK1,ATP6V0A2,PHKG2,PABPC1,CSNK1G3,ABCC1,CIC,MAP4K3,EIF2AK1,KRAS,UHRF1BP1,PTTG1IP,MAP2K2,SLTM,MTR,DAPK3,MASTL,MBIP,RBM25,SNAP23,MYO9A,MAP3K5,CDK2,UNC13C,NRBP1,CDKN2A,CHMP2A,TP53RK,CHERP,TRIP10,RAF1,RPS6KA1,URB2,EIF3D,LYN,TWF2,PRKACA,APP,CHD1,COMMD8,FLAD1,PRKD3,PDK2,SP100,CCDC50,ATP2A2,CDK12,SCYL3,ADCY7,CCT2,BRD4,MAP4K4,PKMYT1,TRIM28,RHBDF2,JAK1,CLK3,FASTK,HIPK2,STK38,MAPK1,SMAD4,PRPF4B,R3HCC1L,SCYL1,ATG2B,CSNK1A1,SCYL2,FOXO3,FGFR3,PTPN11,H2AFY,MYO5A,CAMK2G,PDPK1,GINS1,CSNK1G2,ASPM,NEK7,HAGH,MARK2,MAPK3,NEIL3,MAPK6,WDR91,RPS6KC1,HRAS,HIPK3 |
| 6.930e-04 | -7.27 | ATXN2L (ataxin 2 like) | protein interactions | 11273 | 39 | 15 | 17029 | 2761 |
MEX3C,KLHL20,CUL3,ATXN1,TARDBP,DDX5,BRCA1,FUS,STK17B,POT1,PABPC1,PPP2R2D,PABPC4,ISG15,DDX17 |
| 6.930e-04 | -7.27 | FANCM (Fanconi anemia complementation group M) | protein interactions | 57697 | 39 | 15 | 17029 | 2761 |
FANCL,RPA2,CDKN2AIP,PCNA,FAAP100,RMI2,TOP3A,FUS,UBE2I,BLM,FANCE,RMI1,APP,FANCI,RPA1 |
| 6.930e-04 | -7.27 | NMNAT1 (nicotinamide nucleotide adenylyltransferase 1) | protein interactions | 64802 | 39 | 15 | 17029 | 2761 |
PTPN2,CCNC,PPAN,STAU1,CDCA4,DGCR8,ZNF512,KRAS,KPNA2,ZC3H3,APP,ZC3HAV1,GPATCH4,IFI16,CDC5L |
| 6.930e-04 | -7.27 | DNAJC9 (DnaJ heat shock protein family (Hsp40) member C9) | protein interactions | 23234 | 39 | 15 | 17029 | 2761 |
RPA2,CLIC4,TSTA3,FOXM1,SUZ12,ZNF746,CUL3,MSH2,CUL1,VDAC1,XRCC4,DHX15,PFKP,RPA1,CAND1 |
| 6.946e-04 | -7.27 | BIOCARTA_MAPK_PATHWAY | MSigDB lists | BIOCARTA_MAPK_PATHWAY | 86 | 25 | 17377 | 2626 |
TGFB1,MAX,MAPKAPK3,RPS6KA1,RAF1,RAC1,MAP4K4,MEF2A,MAP4K3,MEF2D,ELK1,MAPK14,MAP2K2,MAPK3,MAP3K4,MKNK1,SHC1,MAPK6,STAT1,CREB1,MAP3K14,MAP3K5,MAPK1,ATF2,HRAS |
| 6.946e-04 | -7.27 | TCTGATA,MIR-361 | MSigDB lists | TCTGATA,MIR-361 | 86 | 25 | 17377 | 2626 |
STAU1,RHOA,DENND1B,MECP2,CPOX,RAC1,USP42,MED13L,SREK1,SND1,ARMC8,ATPAF1,RPA1,RAD23A,CALM2,VEZF1,GOLGA4,PEX5,ADD3,MEX3C,MTMR4,LUC7L3,RAD23B,NUP153,BTF3 |
| 6.946e-04 | -7.27 | BHATTACHARYA_EMBRYONIC_STEM_CELL | MSigDB lists | BHATTACHARYA_EMBRYONIC_STEM_CELL | 86 | 25 | 17377 | 2626 |
CCNC,TK1,NASP,HNRNPAB,PTTG1,RPL6,TPX2,RPS24,AURKB,BRIX1,CCNB1,ARL5B,CCT8,MAD2L2,DTL,EPRS,HSPA4,MTHFD2,FAM83D,SLC16A1,KPNA2,HMGB2,TUBB,HDAC2,LDHB |
| 6.946e-04 | -7.27 | nucleosomal DNA binding | molecular function | GO:0031492 | 45 | 16 | 17224 | 2647 |
HMGN1,H2AFZ,HMGN5,HMGN4,MBD2,MTA2,SMARCA4,H2AFY,ACTB,HMGN3,H3F3A,RBBP4,SMARCE1,MBD3,HDAC2,HMGN2 |
| 6.947e-04 | -7.27 | Regulation of TP53 Activity through Acetylation | REACTOME pathways | R-HSA-6804758 | 31 | 13 | 10287 | 1696 |
BRPF3,CHD3,AKT2,PIN1,MTA2,PML,PIP4K2C,BRD7,RBBP4,MBD3,PIP4K2A,HDAC2,MEAF6 |
| 6.962e-04 | -7.27 | GSE19401_PLN_VS_PEYERS_PATCH_FOLLICULAR_DC_DN | MSigDB lists | GSE19401_PLN_VS_PEYERS_PATCH_FOLLICULAR_DC_DN | 196 | 47 | 17377 | 2626 |
ZNF207,EWSR1,HNRNPAB,TAP1,UCK2,FLOT1,JMJD6,CRLF3,CFLAR,PSMD1,GART,SP100,EIF4A3,AHSA1,PPP4R1,BUD31,TNPO3,UPF2,TAP2,SRSF10,STAU1,TRAFD1,RHOBTB3,KLF10,GUK1,ELL2,SNRPB,MAP4K4,MRPL12,MYBL2,GMFB,PSMB7,PRPF3,ARPC1A,GOSR1,PSMD8,PSMD3,COX5A,NUP62,TICAM1,PRPF4,RGL1,PGAM1,PSMC1,LRP8,SSSCA1,PFKP |
| 6.970e-04 | -7.27 | negative regulation of G2/M transition of mitotic cell cycle | biological process | GO:0010972 | 95 | 27 | 17256 | 2622 |
GPR132,CLSPN,RBX1,PSMA8,TAOK1,PSMB7,MRNIP,CUL1,PSMA1,AURKB,BRCA1,BLM,PSMD9,PSMB9,PSMB3,FANCI,PSMC4,PSMD2,PSMA6,PSMD1,RPS27A,PSMD8,PSMD3,FBXL7,VPS4A,ZNF830,PSMC1 |
| 7.005e-04 | -7.26 | SA_REG_CASCADE_OF_CYCLIN_EXPR | MSigDB lists | SA_REG_CASCADE_OF_CYCLIN_EXPR | 12 | 7 | 17377 | 2626 |
CDKN1B,CCNA2,CDK2,E2F2,E2F4,CDKN2A,E2F1 |
| 7.005e-04 | -7.26 | GO_COPI_VESICLE_COAT | MSigDB lists | GO_COPI_VESICLE_COAT | 12 | 7 | 17377 | 2626 |
TMED7,TMED3,COPA,COPG2,SCYL1,COPB2,COPE |
| 7.005e-04 | -7.26 | GO_HISTONE_H3_K4_TRIMETHYLATION | MSigDB lists | GO_HISTONE_H3_K4_TRIMETHYLATION | 12 | 7 | 17377 | 2626 |
CTR9,TET3,RTF1,BEND3,ARID4A,ZNF335,OGT |
| 7.005e-04 | -7.26 | REACTOME_INHIBITION_OF_REPLICATION_INITIATION_OF_DAMAGED_DNA_BY_RB1_E2F1 | MSigDB lists | REACTOME_INHIBITION_OF_REPLICATION_INITIATION_OF_DAMAGED_DNA_BY_RB1_E2F1 | 12 | 7 | 17377 | 2626 |
POLA2,PPP2CA,RB1,PRIM2,TFDP1,PRIM1,E2F1 |
| 7.006e-04 | -7.26 | GSE37301_PRO_BCELL_VS_GRANULOCYTE_MONOCYTE_PROGENITOR_DN | MSigDB lists | GSE37301_PRO_BCELL_VS_GRANULOCYTE_MONOCYTE_PROGENITOR_DN | 165 | 41 | 17377 | 2626 |
GPR132,FAM129A,FLOT1,ABCB10,BCL2L1,AP3S1,LMNA,CD320,SNUPN,RALB,KIF13B,JAZF1,SLC38A10,CAMK2G,ADCY7,PLK3,ULK3,KLF10,GALC,POLK,MAPKAPK3,NSDHL,CYP20A1,EZR,ATXN1,DNAJA1,IL12RB1,PTTG1IP,ODC1,ARL5B,ECH1,RHOB,ITPRIPL1,DUSP3,ARNTL,ACLY,FKBP5,TMEM159,LONP2,FAF1,NXT2 |
| 7.007e-04 | -7.26 | intrinsic apoptotic signaling pathway | biological process | GO:0097193 | 154 | 39 | 17256 | 2622 |
TMEM109,CDIP1,CUL1,CYCS,BCL2L1,APOPT1,JMY,MOAP1,PDK2,PDCD10,XPA,MSH2,BCL2,FNIP2,TP53BP2,HTRA2,MSH6,PGAP2,BAK1,PRKDC,ERO1A,CUL3,MCL1,TOPORS,BRCA1,DNAJC10,HINT1,HIPK2,E2F1,PML,AEN,DDX5,STK11,CHEK2,MAP3K5,E2F2,ZMAT3,HRAS,IFI16 |
| 7.013e-04 | -7.26 | CHMP4B (charged multivesicular body protein 4B) | protein interactions | 128866 | 103 | 30 | 17029 | 2761 |
KDM3B,CHMP2A,COX15,PDCD6IP,MECP2,RAB7A,RPL6,DNAAF5,FLOT1,ATP6V0A1,CTCF,EXOSC9,CAPZA2,UBE2I,PCGF1,ATP6V1B2,VDAC1,CHMP2B,FBXO5,SMC3,CHMP4A,HIPK2,CAPN7,PIAS2,SARAF,CHMP4B,VPS4A,TFG,MVP,ATP6V0D1 |
| 7.045e-04 | -7.26 | endometrioid_carcinoma | COSMIC cancer mutations | endometrioid_carcinoma | 16178 | 2445 | 17385 | 2587 |
HECA,ZBTB10,ABCC10,HEXB,TGOLN2,CCNL2,FBXO22,EEF2K,THAP4,RAD23B,ATP13A3,DNM2,FTSJ3,USP34,CCDC57,ERCC1,NRAS,EHMT1,KIF15,HNRNPF,WDHD1,MIER2,DIDO1,RAB22A,SMAD2,MID1IP1,RPS27A,MYO18A,OGT,MPV17,COX5A,SMAD1,ZNF75A,ANXA11,SLC25A33,ZNF720,SEC61G,GGA1,MUM1,CCZ1,TRIO,RAB23,KCTD17,HAUS4,EIF2AK4,APH1B,PARN,CDC73,MYL6B,ATG4A,TMEM179B,ERV3-1,SMC3,C4orf3,GEMIN4,MVP,NUP85,PPP6R1,PABPC1,NSUN4,PPA1,IFRD1,AGGF1,FOXK1,RBM42,GTPBP4,MAP7D1,MRPL16,ELK1,EIF4H,RDH11,MAGED2,KPNA1,ETS2,TYW5,WIPI2,RUFY3,PDLIM5,ACSF2,FAM72D,RHOG,EXOC3,STARD7,C5orf30,VTI1A,INO80E,SLC35B2,LCLAT1,RCOR3,CPNE3,KIAA1147,RBM23,ZNF420,AHCTF1,TBC1D22A,TBC1D14,GMEB1,NSFL1C,SEPT11,GPD1L,ZC3H3,PDCL3,SNX8,ERMP1,EID1,IDH3A,POLR2D,HTATIP2,MEF2D,TMEM147,GSTCD,TANC1,MAT2A,VPS26B,NSMCE2,CORO1C,CAMKMT,PPP5C,PITRM1,TUBB,COMMD10,ZNF445,HABP4,CCM2,FLOT1,BTN3A1,ATG2B,ABHD14B,PPP1R3B,GOLM1,ZBTB45,HUWE1,ZNF260,NAA50,ANXA5,LTN1,UBE3B,NAP1L4,ZNF710,ST8SIA2,RPL22L1,MED22,SPTAN1,STAU1,DDX24,TCTEX1D2,TACC1,MRS2,LDHA,HEBP2,LLPH,RAB3IP,TTC33,PICALM,SH3BP5,SLC19A1,ACOX1,FAM3C,AEN,PARP10,YWHAH,THAP5,GPATCH4,FAM129A,TRIM11,YTHDC2,SNX15,RBM8A,ENSA,NENF,SND1,RUFY1,TRIM65,ZER1,PRNP,KRR1,RAB8A,NUP210,NT5DC1,NOC2L,EIF5,TACC3,RYBP,VPS13B,PTPN18,MIOS,MBLAC2,SNRPB,CDC6,UTP3,PBRM1,ODC1,USP21,TRAM2,FBXO28,BCL7C,ARRDC1,ADAM9,DVL1,NUMB,ZNF564,C1orf74,CTU2,PARP12,ZCCHC9,CENPF,LAMTOR3,CHCHD2,NCKAP1,LYRM2,RSAD1,TNS3,SUB1,RINL,SSBP3,KIF13B,MBD2,XPA,AHCY,RBM3,GLE1,MRPL48,LRSAM1,HDHD2,NTPCR,NSDHL,AMD1,CAMSAP1,ZNF761,METTL22,ICAM2,STYXL1,APPL1,BBS12,RXRB,SDHB,PCM1,GALNT2,TMEM168,NLRC5,BTBD10,MYO9A,CCNB2,USP7,GLT8D1,RPLP2,SUCLG1,ARID2,TMX4,SLC2A1,ATP6V1B2,PCBP1,LYN,BCAP31,VAV1,TMEM69,MRPL50,PSMA6,ZNF473,ZNF302,BRPF3,TARDBP,BCAP29,CTDSP2,PRPF19,PPIF,KDM3B,MND1,CLCN3,BIRC3,RAB7A,ANKRD33B,PPIE,CHMP2B,VDAC1,EIF3H,TMEM201,GLOD4,IDE,DHX16,UHRF2,XRCC3,CHMP4B,PARD3,BCL2L12,C19orf53,KLHL21,PDAP1,TMX3,CDCA8,GTF3A,ARF1,SLC12A9,TUBGCP2,DNAJB9,HOMER1,POLR1B,RNF5,RBM15B,PPAN,RHOA,RPRD1A,BTAF1,TOP3A,ARHGEF12,PCGF1,DDX23,RAB18,CACNB1,TRIM26,PDCD6,ATP6V1D,L3MBTL3,FAM110A,NEIL3,CTBS,BBX,IMPDH1,TAF12,NR2F2,PGAM1,HIPK3,IFI16,NUP188,TXN,H2AFZ,PNISR,PRKCSH,USP39,UBE2I,SLC25A37,ASPHD2,ZNF428,RAB4A,TRA2B,SUCLG2,CISD2,TAF5L,ZNF800,CDC5L,ZNF524,SGCE,OSBP2,NSUN2,USP22,CLNS1A,EIF3A,ZMYM3,DOT1L,IWS1,ANKRD10,WAS,KIF18B,TPP2,C1orf109,ZMAT3,B4GALT2,PRPF38B,RECQL,C9orf78,EWSR1,GADD45G,RRM1,ACAP1,B4GALT1,CYCS,SUPT7L,TMEM165,NPLOC4,CNOT3,SPAG5,WDR48,RTKN,CEP104,EXOSC7,KLHL5,LRRC8D,MSH2,PIGG,OSTF1,FBXL7,MRPL40,TNRC18,SYTL3,FAM171A1,APOL1,EIF5A,GCC2,PRIM2,ELL2,RDH10,MFNG,RPS24,GORASP2,CAPZA2,ADRB2,CCT8,MTR,PHF6,PFDN5,SLCO4A1,TTC13,GOLGA2,RBMX,MED15,PIAS2,APPL2,SAMD8,NUDT3,CDKN2A,ZNF511,ATXN3,RAF1,KIAA0232,C2orf49,CD320,EPM2A,CCNA2,MTMR4,BRI3,TP53BP2,AQR,RBM12B,ILKAP,CDK12,SAP30,BRD4,DRAP1,NARF,LRRC8A,ELP4,ABHD11,PKMYT1,ASB13,SERP1,TRIM28,SUPT16H,EIF3K,CHMP4A,CBWD1,ATF6,XRCC4,ADAM23,PRPF4B,NDUFS1,DEPDC1,MECP2,SECISBP2,HMG20A,WWP2,JAKMIP1,SLC25A36,CCNK,DNAJC8,AXIN2,JMJD4,ANKRD37,KAT2A,TMEM126B,RABIF,ADSL,PACS1,BMS1,KCNQ1,OTUD3,ARSK,MACF1,KIF11,COMMD4,KLF6,SMAP2,FADD,SH3GLB1,MYO1F,CBX3,TMEM127,INF2,DUSP11,DDX5,WDR62,TAF6,ESPL1,DDB1,DEF6,FAM83G,IPO4,UBL3,NAT9,PIGM,LYRM4,GPR132,UBE2Q1,PTP4A3,BRIX1,MRPL19,ZNF696,SF3B2,PCYOX1L,CDC42,SYNM,GOT2,JAZF1,HADHB,RPF2,SLC35C2,CNNM3,CARM1,SRPK2,WDR41,LARS,ZCCHC10,CCDC138,LRBA,TMEM216,SUMF2,KMT2C,OGFR,PRPSAP1,ASF1B,RPL37,MAN2A2,EIF4ENIF1,NIP7,U2SURP,MIA2,ZNF268,VPS4A,PPP1R2,PM20D2,XPNPEP3,RGS2,LYAR,POLR2I,TRAFD1,SUGP2,GBA,EIF2A,SYVN1,CCDC71L,DAPK3,ARHGAP15,MASTL,UAP1,NFIL3,FN3KRP,YWHAZ,CTSA,TMEM14A,TOB1,TSEN15,ADNP2,TCF12,PRKAB1,MDH2,SMARCA4,ORC1,RRN3,UBXN2A,IARS,CD3EAP,KIF14,EXOSC1,CS,CLTB,CSTF1,POU2AF1,UBQLN4,NXT1,HPDL,PGGT1B,SELPLG,SMU1,ATXN1,GLO1,OGDH,BICD2,CADM1,EDEM2,HERPUD2,TOLLIP,FANCE,MBD3,PDHX,RPS9,ALKBH6,SURF4,DUS3L,ARNTL,ANP32E,FKBP5,TMEM101,CCDC125,ABCA1,PDCD2L,GCLM,RAE1,DCTN2,NUP54,CHIC2,PAWR,MXD4,DCUN1D4,PIP4K2A,XPR1,FERMT3,KIF5B,KLHL20,SEC24C,RRBP1,ARHGEF2,ANP32A,LDLRAD3,STAT3,MYO5A,NIPAL3,TXNL1,PHF20L1,DCAF6,FAM49B,TMEM39A,ATP2C1,RFFL,COG1,RCOR1,PRMT2,TFEB,LEMD2,UPF1,ELMO1,ZC3H7B,DTX4,ZMIZ1,TERF1,HRAS,CCDC93,TMED7,PIGQ,CNTROB,PPP1R16B,MIS12,GSDMB,TTC9C,PDS5B,NUP153,PGAP2,TMEM115,PLEKHM3,DCUN1D5,PLEKHF2,BRMS1,PWWP2B,TRIM47,WDR11,AXIN1,SMG9,TRIM52,LONP2,NDUFV2,PHF23,CERK,SLC4A2,EZH1,ITGB5,LMNA,MCTS1,DDX56,EIF2S2,SLC38A5,FOXN2,CARS2,PRRC2A,C16orf72,RB1CC1,ZMYND11,PGS1,MYBL2,UHRF1BP1,MPG,MATR3,CYB5A,NCDN,POLR2J,SETD3,TEX30,PTAR1,CNOT6,NDE1,EGLN1,ZNF207,ANKRD27,ABCA3,SARNP,IVNS1ABP,RMI2,MON1B,TMEM97,NIT2,NUF2,ZNF267,TMEM161B,APP,PRKD3,CLUAP1,ATP2A2,UTP18,GRSF1,DUT,ZCCHC2,ANAPC7,RNF19A,FAM76B,TMEM9,GCC1,RNF169,ADCY7,ATP6V1G1,ENPP4,RNPS1,CDCA2,FKBP3,GPR137,DDX17,CHCHD3,PEX5,CDC16,HIPK2,MBOAT1,TICAM1,PDXK,ZBTB11,ANXA6,TMBIM4,GMCL1,UBE4A,ETS1,WRB,ZNF92,PNO1,CAPN2,ADD3,SUV39H2,TTLL12,TPCN1,TMX1,LYPLA2,HNRNPM,MFSD12,LDHB,PPP3CA,NUDT8,POLK,JTB,EMP3,MTMR12,ZP3,PDE3B,KIF18A,CCDC6,MAPK6,C4orf46,LY75,SLC25A19,RGL1,PSAP,WDR76,IGBP1,FAF1,SNAPIN,COX15,THOC1,AGRN,GNPDA1,GPBP1L1,PPP1R15B,CSNK2A1,EBNA1BP2,GIT2,BIRC2,ATPAF1,DLG5,ABL2,XRCC2,ZFYVE27,MCMBP,PTPRK,CDC37,METTL1,HARS,GMFB,ESYT1,ANLN,RAB5B,RHEB,DPYSL3,TBC1D17,TIMM13,CDCA4,TONSL,NRM,NAGLU,ACTB,ZNF45,TMUB1,CTCF,ASAH1,DOCK11,CRLF3,ASXL2,LRRC14,NUS1,SLC27A4,MDFIC,MAML1,CYTH1,NQO2,UTP15,EIF2AK1,EIF4G2,ZDHHC3,MOSPD3,ITPRIPL1,CDC27,SNAP23,TBPL1,PRMT7,KCTD7,NDUFA5,CYLD,UGP2,DYNLL1,COPE,HCFC1R1,ZADH2,GGPS1,RPAIN,RAD23A,ATP6V0B,PDK2,STRBP,DUS4L,MRPL34,PDCD2,SLC39A9,CLPTM1,RPL29,RPL35,DNAJC9,MTMR6,NFATC2,KDM1B,ARL5B,USP36,CCDC127,MRPL2,ATP1A1,CLK3,PSMD3,MAFK,CEP55,DNAJC17,ZNF436,NCOA1,SLC25A39,ZC3HC1,ZNF146,ATXN7L2,CDC40,GOLIM4,SMAP1,RRP15,DAP,GNE,SMC6,ARFIP2,NKRF,CHAC2,BZW2,WRNIP1,CENPM,PTGES3,CAMK2G,MLEC,ZNF202,PPWD1,FAM50B,RHOT2,TPD52L2,GOLGA7,TWSG1,PGRMC1,GLG1,FAM126A,RPS6KC1,UBE2C,PPCS,NDUFB6,TMEM41B,ZDHHC8,PLXNA1,CCNB1,SLC20A1,COMMD6,ABHD14A,C14orf119,ASAP2,SNUPN,CNPY4,PLCL2,SEH1L,ATG9A,PBK,MKI67,DDX20,AMDHD2,SLC17A5,GALNT7,CCNF,FOXRED1,RBM47,PTER,WDR4,DHTKD1,TRAF5,HDAC2,PWWP2A,HSPH1,MAPRE1,CHTF18,KIF23,SLC35B1,NOTCH2,PMF1,COPG2,JMY,FKBP1A,SLC31A1,SNX18,CTPS1,ATP6V0A2,PIKFYVE,RNF135,LPCAT1,EEF1D,TMED2,PHF10,FTL,DDX28,SIGMAR1,PIP4K2C,FAM133B,RIT1,PLEC,KDM3A,SF3A2,FAS,EPRS,ZNF777,TMEM54,QARS,TCOF1,CABLES1,NRBP1,DNMT3A,RWDD1,CKLF,TRIP10,SF3B1,RPS6KA1,SUZ12,CAST,RAC1,GPR89A,OLA1,SNN,GNB2,FLAD1,APLP2,KDM2A,TNPO2,CDKN1B,TALDO1,GPX4,ATP13A1,MAPRE2,RFC3,ERF,CUL3,SLBP,KIAA1586,H2AFV,POLG2,GAR1,PSMB9,DHX57,NSA2,HSPA4,MRPL55,JAK1,TBL3,GOLGA8A,SEL1L,H2AFX,KLHDC4,B4GALT3,PDCD11,ATMIN,POLQ,POU3F2,OTUD5,NCOR2,ANKRD13D,PKP4,SCAMP3,BABAM1,CDCA3,SLC25A12,BLM,TMCC3,GTF2F1,RPL17,CRAT,AHSA1,PRC1,UPF2,COPS7B,SLC38A10,CNOT6L,CNPY3,IFT46,TSHZ1,ZFP64,DENND4C,DENND1B,WDR18,RPL8,ILF3,LRRC1,RHOT1,TSR2,MARK2,ECH1,PRDX1,PLD3,NUCB1,GNA12,FBXO21,C1orf131,PRDX3,PFDN4,HNRNPH3,STX18,TFDP1,KHSRP,ASNA1,CPEB2,SSSCA1,VPS29,BYSL,S100PBP,MIB2,PTMS,NOP2,UBN1,DCAF15,NF1,FLYWCH2,ALKBH5,MOGS,UBE2Z,TAF6L,BECN1,MAPK14,SNAPC4,RNF103,BCAT2,MBD4,C18orf32,METTL14,ZNHIT6,IMPAD1,RCSD1,PHTF1,SRI,KIF22,ZBTB22,NFU1,OGG1,TRIM14,ELOF1,COPS8,FYTTD1,TRIM8,RRM2,SOX4,ABHD5,UBTF,CXXC4,PAF1,UEVLD,SPATA2,PQBP1,IARS2,ATXN2L,GALNT10,STARD3NL,RPS15,PIGN,AGTRAP,CIB1,XPO7,SRRT,ZNF449,CAPZA1,GLTP,BCL2,KIFAP3,N4BP2,HP1BP3,VOPP1,THNSL1,ISG15,CAND1,C22orf46,GNAS,TSC1,RBM25,CDCA5,ZFP90,NANP,RBBP4,ZBTB24,SMARCD1,MBD1,WASF2,MMACHC,GNPNAT1,MPHOSPH8,HNRNPUL2,CHD1,MEAF6,C2orf68,CCDC50,AKAP8,PARL,RPN2,CHTOP,FAM3A,F2R,SCYL3,ABI1,HTRA2,MOSPD1,RLIM,FAM172A,ZNF500,PSMB7,NLN,WIPF1,BOLA1,BUD13,NDUFB1,PEF1,EIF3G,BTBD1,TAB2,TULP3,WDR59,CANT1,SCARB1,GAS2,USP11,SMURF1,PPP2R2D,TSPAN5,CDS2,MAGEH1,MRPL42,EYA1,MRPS26,LETMD1,HDDC2,RGS1,MAN1A1,FBXO5,GART,PELO,TANK,BRD7,MRPL11,SAMD4B,ZDHHC18,GTF3C6,POLR3GL,WDR81,MEN1,ZNF407,MFN2,COX8A,ZRANB2,MBD6,SRSF3,ATP6V1C1,IDH3B,TATDN1,TSC2,LACTB2,CMTM6,RBM4,ZNF275,ANKRD39,RPL23A,CDKN2C,NAPG,USF1,DNAAF2,MECR,AP1M1,UPRT,CRY2,ECD,MOB1A,RNF26,TIPARP,LRRC59,RHBDD2,MGAT5,BAK1,ZNF559,RHOBTB3,GABPA,WBP1,NUTF2,ARF4,GINS4,KRIT1,BOLA3,AHNAK,RAD18,PDRG1,RNASEL,CHPF2,OAZ1,PDCD4,SMNDC1,NXT2,HIVEP3,KIAA0100,CLSPN,RHOC,DHX9,PDCD7,PSMD9,HAUS2,COPB2,CD59,TFAP4,RNFT1,MEGF8,RIMS3,FBXO7,EFTUD2,CPSF4,MRPL21,PHKG2,LUC7L2,EIF3L,MTA2,TYW1,USP10,ITM2A,SSR2,MTX1,SFXN5,FNTA,PDLIM1,TXNDC16,ZNF830,TMEM159,MRPL3,ALS2,FAM72A,TRIM41,KARS,NQO1,POC1A,ANK3,PTTG1,TPX2,TBC1D13,GLRX3,STMN1,C19orf48,REPS1,ABHD16A,FBXL6,SH3BP1,MTA1,UBA5,CLCN6,INTS12,C8orf59,RPRD1B,SZRD1,CGGBP1,CPNE1,SEC61B,FAM118B,GOPC,E2F3,CIRBP,RPL38,CRNKL1,PFKFB3,GORAB,RAB1A,GIGYF1,TMEM184C,PPP2CA,KIF2A,CCDC14,LSM6,RNF38,SNRPG,CENPBD1,DMWD,USP13,MZT1,ZFP91,TRMT6,IP6K2,WDR5,SLC25A43,IFT27,PMVK,NEIL2,RRP36,SRXN1,RPA2,PSMD2,CLIC4,PDCD10,CBWD2,COQ4,ITGB8,ARF5,ARHGEF1,FBXL19,GTF2H2,TTPAL,UTP20,MAGT1,GPS2,DBI,MRFAP1L1,CD81,TMEM131,WDR13,FANCI,PAPOLA,CREM,TET3,FANCL,GLIS2,IL6ST,INTS1,POP7,SLC44A1,MTPN,ASB6,PLK1,SEPT9,CELSR2,RBX1,RAD51AP1,ZBED5,CKAP2L,PSMG1,UBE2V1,EAF2,IL12RB1,KRTCAP2,LUC7L,LSG1,NECAP2,TRIM4,ALG3,AGPAT2,CHD3,ZNF367,E2F4,PRPF4,KPNA2,BEND6,CLN3,DNAJC30,FAM208A,NGLY1,POT1,MYL12B,CCDC137,RMND5A,HJURP,PHB2,DNAJB2,FAM53C,SDC2,KLC1,CDK13,ADCK5,COX4I1,DNAJB1,RAB6A,ARID1B,C1GALT1,MLX,UBE2Q2,CCP110,ZNF746,ARL6IP1,CTR9,NIPSNAP1,ABHD2,DCAF8,ACSL3,LDB1,MAP4K3,ARMC8,RBM38,NMT2,IRF5,HAUS8,MBIP,COX7A2L,ZDHHC7,SIL1,FAM122A,DTD1,UNC13C,BCCIP,SART1,TRAF7,NDUFAF2,TOR1AIP1,ZNF416,LAGE3,ZFYVE21,TM9SF3,RRAGC,ZNF121,OIP5,NRF1,WDR44,PPME1,EFCAB11,RPAP1,CABLES2,LMAN1,AHCYL1,TOP1MT,STRAP,SPSB3,ZNF583,SNX25,ARHGAP17,ZNF780B,PPT1,NUP155,DCLRE1C,MRPS14,RHBDF2,SUGP1,RBL1,FASTK,UBXN2B,STK38,AP1S1,SPRYD4,SLC22A23,H3F3A,CHID1,SMAD4,RAD51D,SLC30A9,CMAS,UNK,NADSYN1,HMGN3,NCAPG,SCYL2,FZD6,HERC3,GTPBP3,CTSS,ORC3,RNLS,YTHDC1,ACP2,HMGN5,CSRP1,METTL5,ABCF2,TUFM,RANGAP1,PNPLA8,HAGH,API5,ZFR,SEC23IP,E2F1,USP20,RBPJ,PDCD6IP,MAX,GXYLT1,LUZP1,ADAM10,CXXC1,TSC22D3,AP3M2,CUL1,GYG1,NANS,OAT,MYEF2,ANKRD26,PA2G4,NOL11,FIZ1,ZNF200,MARCH2,SLC26A2,SRP72,KLF10,LACTB,RFC2,RAB2B,PRIM1,MAP3K4,HHEX,LUC7L3,MAP4,MRPL27,BTF3,PTPDC1,NMD3,CCDC59,PTOV1,COX5B,DNAJC5,SCOC,DHPS,POLR2K,ANKH,PRKAA1,VAV2,C16orf87,GSPT2,TATDN3,DLGAP4,PRPF39,PSEN1,ZNF79,PDXDC1,VPS25,NDUFS7,YY1AP1,C12orf10,FAM192A,RPN1,LHX8,ARPC5,ZNRF2,TPST1,DAPK1,PIK3IP1,CYC1,SOCS5,FDFT1,PIGT,EMB,WDR1,ZNF574,C1orf35,EXOSC9,ARID1A,PTTG1IP,FXR1,GOSR1,MAP2K2,TWISTNB,AKAP1,XRCC5,HMGN2,PI4K2A,CAT,DERL1,HSPBP1,MTHFD2,CEBPG,ARAP1,USP32,FAM83D,CABIN1,SMPD4,GPI,CYTIP,TP53RK,REPS2,RAB11B,UROD,SLC39A13,POMP,BCL2L1,NUDT19,DECR1,RALB,SIAH1,ADCY9,LPIN2,MRPS27,SOCS6,TTC3,RNASEH2A,CFL1,ANKLE2,CDC123,VDAC2,ERC1,AMZ2,ANKZF1,RAD51C,ZNF282,DSN1,DDOST,HINT1,DGCR8,SAFB,RWDD4,FTSJ1,LMBR1,NCLN,BEND3,EYA2,DYNC1LI2,MANBA,B4GALT5,SLC41A1,FAM76A,TKT,CBLL1,ARGLU1,LANCL1,POFUT1,FAM8A1,HEATR5B,HLA-A,EBP,RFWD3,NDUFA2,FUT8,FJX1,BTF3L4,PTPN11,MRPL54,FEM1B,RPL19,CNN2,NDUFA3,MTX2,MSH6,PDLIM2,LONRF3,RFXANK,FBXO9,GUF1,RPL32,ZHX1,OAZ2,NDUFS5,WDR91,HIGD2A,POLA2,ZNF76,MTX3,COPA,UQCR10,HMGXB3,PHRF1,ABCB10,COMMD5,MAP1LC3B,DST,RAB35,SIVA1,GPATCH1,TCEA1,DRAM2,DEAF1,SNRNP200,LAP3,NCK1,VHL,SREK1,ARHGDIB,PITPNB,HSPB11,BRWD1,PPM1G,SH3GLB2,CRCP,BAZ1B,ACBD4,STK11,CLU,CHEK2,ZSWIM3,TSTD2,CHPT1,MRPL13,DCAF5,CAPN1,UBE2D3,NSMCE4A,PPP1R12A,ZCCHC8,GORASP1,UBXN1,NACA,RPL15,EPN1,PCSK7,THRAP3,QSOX2,TTF1,NUP205,PRPF18,CHKA,DTL,ZRANB1,SLC12A2,ATP6V0D1,CSNK1G3,CREG1,NUDT4,RPL6,VKORC1,SLTM,EVC2,KLHL15,SIAH2,SLC16A1,EHD4,SNRNP70,C11orf1,APOL2,N4BP2L2,CHMP2A,CORO7,FEZ2,PMS2,UCK2,UCK1,CLCC1,EXT2,MXD1,USP5,HNRNPA2B1,SAP130,NVL,PPP6C,CYB5R1,ZNF770,EBAG9,RNF25,PCGF6,METTL2A,FAM72B,PON2,HNRNPR,HPS5,STAT6,MAPK1,BRD9,TMEM33,NAT14,DNAJC2,TRIP12,SHPRH,SCYL1,VPS45,MYO9B,GFM2,SPPL2A,FASTKD3,FGFR3,PPIG,ZDHHC13,TMEM99,H2AFY,ATG13,NDUFS8,ERI3,FBL,SLC35A1,FRMD8,MICAL3,TGFB1,ELOVL5,HEMK1,TIMMDC1,HELB,PSPC1,MIER1,SCFD2,NDRG3,CDK11A,MEGF9,ACAT1,CENPT,PLOD3,RAB3IL1,ZSWIM6,RAB14,ADD1,MRPS15,KDM4A,XIAP,DHX8,GLUD1,ANKRD23,PABPC4,CALM2,CDK5,PSMD1,NEK6,NSRP1,RABGAP1L,SRSF4,FNIP2,KCNAB2,PCBP2,MLST8,PLK3,ZNF672,MRPL43,HSDL1,MCL1,SMC2,PPFIA3,ICMT,SLC50A1,STOML2,LIMK1,ZNF689,PRDX5,ATE1,MLYCD,ATP6V0C,ST3GAL2,FBXL3,E2F2,PFKP,AAAS,DDX42,SSRP1,MRPL9,MRPS2,STRN4,TOP2B,ZNRF3,TMED3,DDRGK1,RAVER2,GNS,INTS7,INPP5A,MCM5,PHF14,ZNF326,UBE2QL1,NAGPA,TIMM8B,ETV3,TSPYL4,TSPAN31,DHX29,TEX10,MAN1B1,RPS10,CBFA2T2,ABCF1,RHOB,LRRC14B,DTWD1,PTPRF,SCARB2,OSBPL11,CCDC86,DUSP3,SLAIN1,MDH1,HEXA,RNF139,SNX14,ZNF296,TRERF1,UBR2,CHD1L,ACTR3,WDTC1,MYH9,CREBL2,NIPA2,PRKACA,SAFB2,ANKIB1,STAM,ARL6IP6,RAB21,SP100,ZKSCAN1,DDA1,NUP107,ANKRD13C,MAVS,CEP63,TMEM136,ATF2,DCTN1,SHOC2,PSRC1,MAP4K4,WBP2,ATP6V0A1,NUSAP1,DNAJA1,TAZ,C19orf54,TAF2,SEC61A1,WDR7,RPLP1,CBLN2,FUS,LRP8,COIL,LRCH1,GALK1,ZNF786,RPS2,SESTD1,TRAK1,JMJD6,SIKE1,AKT1S1,KRI1,FBXO3,ERH,GATC,PPP1R8,PRDM4,GTSE1,GEMIN6,DCP1A,SGCB,IMPA2,NUDC,PDPK1,TK1,GUK1,TNFAIP3,GALC,ZNF512,KIAA0930,MRPS10,DDX39A,RPA1,ZNF180,ZNF862,KEAP1,POLE,TATDN2,PITX1,CAPN7,LRPPRC,PML,HMGB2,USF2,ANAPC4,SRM,DDX47,MCCC1,S1PR2,CDIPT,SEC16A,SSR1,LIN9,PCNA,ZNF639,TRMU,PIK3R2,ETV6,TXLNA,PPCDC,FAM86C1,MYBL1,MRPL32,CCAR1,ABCC5,PBXIP1,BAZ2A,TLK1,MRPL12,EZR,LNX2,LRP5,BRCA1,PRKRA,STX16,EPB41,OPTN,SEPT1,SOCS4,QRSL1,PIEZO1,OSGEPL1,GLCCI1,NUDT11,NAA60,GEMIN7,SEPHS2,LZTR1,RACGAP1,PPP3CB,B4GALT4,RLF,RAPGEF6,SNRNP25,RB1,VASP,MED8,VMP1,PPIL2,MEA1,TIMELESS,AHDC1,ALDH18A1,TMEM8A,ABCC1,PREB,TRAPPC9,AACS,MEMO1,KRAS,RTF1,UBE4B,NFATC2IP,LY6E,ARPC1A,ZNF174,PSMC4,GOLGA4,PALB2,SYNCRIP,PRPS2,NIPA1,TIGD2,RNF114,FOXM1,MRPL39,XAB2,SUMO2,DUSP22,COMMD8,RPL11,CSDE1,MDM2,CORO1A,MINPP1,METTL9,POC5,DVL2,GM2A,PSMA8,COQ10B,CPOX,SLC26A6,CYP20A1,PRPF3,RPSA,SRSF1,DNAJC10,ZNF700,SCAP,PLEKHG4B,TIMM17A,TOMM6,FAU,LTA4H,AP2S1,USP53,INTS2,CTDP1,MIF4GD,CDT1,ARID5A,SUMF1,GGA2,AP3S1,CSNK1A1,RMI1,TFRC,PTPN2,STARD9,GSTK1,NDUFV1,SLC1A4,CWC27,SLC35B4,DDX31,ABCD1,RPAP3,CNTN5,SNX2,ZMYM5,CCDC34,CHCHD6,BSDC1,KPNA4,CDKN2AIPNL,FBXO41,BIRC5,TFE3,SNAP29,CDCA7L,PKD2,ACADM,CHMP7,SAT2,GCSH,ZNF496,TMEM109,TAP1,YTHDF3,NHLRC3,IKBIP,EIF1B,ELMOD2,KIFC1,DBNDD1,CYB5RL,PARPBP,RNASEK,CDC25B,PRADC1,DNMT1,NOL12,ORAI2,USO1,AKT2,NOL8,GNG7,AURKB,MCFD2,SLC25A5,ZFAND5,MAK16,STT3A,TMED10,PSMD8,EIF2D,ITGB1,PTPN7,UQCRH,RRS1,ARRB2,RTN3,ZNF598,SVIP,DDX58,WSB2,PPIB,MUT,HLA-E,NDUFA4,MAN2B1,METTL3,CFLAR,NDUFS4,RNF121,MEX3C,KLF16,HDAC7,DAD1,BDH1,PCYT2,GNAI2,ANKHD1,MORC3,TERF2,KCTD20,SEPT8,DCTD,PKM,TOMM40,PATL1,ADSS,SERTAD2,ZFP92,NSF,DCK,ERGIC3,ACLY,LPCAT4,VCPIP1,YY1,PPP6R3,MAP3K5,PPP6R2,RNF14,CDK2,ZC3HAV1,SYS1,ZBTB37,URB2,EIF3D,MAGED1,KLHL18,ADPGK,SLC25A44,AP1B1,SDHA,PHC2,CRKL,MOAP1,TERF2IP,CYHR1,ZNF75D,SHC1,UCHL5,NAA35,TMBIM1,CCT2,CDKN2AIP,MKLN1,HMGN4,LYRM1,GALK2,CDC23,SHCBP1,AP4E1,PRDM11,VEZF1,PPP2R5A,ACYP1,STAT1,PPA2,TRIM32,C1orf112,TCF3,MRI1,BRAP,AGPAT3,MYNN,SDF2L1,SPR,RAB11A,REEP5,FOXO3,MAD2L2,CCDC28A,RBM17,MAT2B,PTEN,CENPJ,TAGLN2,OSTC,PACS2,NCOA2,SMC4,NEK7,NET1,PARP4,TBRG4,ANAPC2,RPL27A,YIF1A,SGSH,HGS,TTLL4,SLC38A7,MFAP1,CCDC69,BRWD3,ESYT2,SKA3,NPHP4,UBE2E2,HNRNPAB,PLXNC1,ST13,TMEM184B,DNAJC24,ZNF107,KIF2C,SLC29A1,AGFG1,SIRT2,FKBP2,USP48,UBQLN2,SNRPD3,CUTC,EDC3,UBLCP1,ZNF804A,RAP1A,THADA,EIF4A3,ATG3,DPYSL2,PPP1R12C,AKR1B1,JOSD1,RP2,TTC4,TECR,ARID4A,FGFR1OP2,TIMM50,TDP1,DPM1,FOPNL,SLC16A7,SLC25A22,STK17B,DHX15,CHAF1A,GEMIN5,COPS6,SASS6,RPS26,PSMC1,SLC12A7,TBC1D12,TM9SF4,ZNF768,UFC1,MED13L,TIA1,MEF2A,EPHX2,PITHD1,RHBDD1,NFATC3,BANF1,BUD31,ZNF335,YBX1,KNTC1,ACAD8,UBE3C,ZNF189,ALDH9A1,KDELR1,TSTA3,CIC,OXR1,SEPT7,TMEM241,NAP1L1,NSMF,ODF2,EXOC4,KIAA1328,NUP62,PITPNA,NAA20,PTDSS1,MZT2B,PDSS2,C7orf26,TMEM106C,IMMT,ASH1L,CHERP,WDYHV1,PLAGL2,CHKB,IRF3,TWF2,PAIP1,ANKRD28,ANKLE1,FARSA,SAR1A,SCAMP4,APOOL,PDIA6,ACSL5,TOR1AIP2,AZI2,GFER,RAD54B,TMEM41A,DAP3,ZNF317,GADD45B,AKNA,CBX4,KIF3B,GOLPH3L,SH2D3A,CASP6,TOR3A,SRGN,DBF4,MFSD10,SAC3D1,CTNNBL1,YIF1B,CLDND1,TTC17,SLC25A1,GINS1,PAQR6,CSNK1G2,TELO2,ADAM17,HMGN1,NASP,ASPM,PPP1R21,PRKAR1B,SYMPK,TARS,SNRPA,MAPK3,HLA-B,ATAD2,PLAA,ZNF330,OSBPL8,KBTBD7,PREPL |
| 7.048e-04 | -7.26 | BYSTRYKH_HEMATOPOIESIS_STEM_CELL_QTL_CIS | MSigDB lists | BYSTRYKH_HEMATOPOIESIS_STEM_CELL_QTL_CIS | 110 | 30 | 17377 | 2626 |
GGNBP2,SCOC,CSRP1,AGTRAP,HARS,CREG1,NSDHL,FLOT1,GLO1,ADPGK,IL12RB1,CBFA2T2,ATP6V1B2,GFER,PDXDC1,ZNF275,NECAP2,GEMIN5,PTPRF,PON2,DAP3,DDOST,DBI,ARNTL,ARL6IP1,GPI,F2R,MYO5A,IFI16,ALDH9A1 |
| 7.050e-04 | -7.26 | Golgi cisterna | cellular component | GO:0031985 | 112 | 30 | 18223 | 2701 |
MOB4,NAGPA,B3GALT6,TMEM115,GOLIM4,GOLPH3L,APH1A,B4GALT5,GPR89A,B4GALT1,TMED3,B4GALT4,GOSR1,STX16,BCAP31,RAB21,NUCB1,GALNT2,ASAP2,GOLGA2,GOLGA8A,FUT8,ARAP1,CANT1,ST3GAL2,B4GALT3,CHPF2,B4GALT2,GPR89B,TMED2 |
| 7.053e-04 | -7.26 | COP1 (COP1, E3 ubiquitin ligase) | protein interactions | 64326 | 94 | 28 | 17029 | 2761 |
COPS8,CCT2,AGGF1,RBX1,RB1CC1,PARP4,CUL3,CUL1,WDR5,ETS1,CCT8,PPP2CA,MDM2,ETS2,DDA1,NFIL3,PTPN11,DCAF11,CDKN1B,ATF6,YWHAZ,COPS7B,KLHL42,COPS6,MVP,STAT3,PPP2R2D,DDB1 |
| 7.053e-04 | -7.26 | RABGEF1 (RAB guanine nucleotide exchange factor 1) | protein interactions | 27342 | 94 | 28 | 17029 | 2761 |
UBE2D3,OTUD5,CCDC93,MAX,RPRD1A,THOC1,GGA1,MON1B,RCOR1,NUF2,GGA2,DAZAP2,PSMD9,GIT2,BIRC2,RAB22A,HMG20A,OIP5,CYHR1,RAB21,CIPC,RPS27A,GRIPAP1,RABGAP1L,RAB4A,ARNTL,MAPK1,HRAS |
| 7.063e-04 | -7.26 | UBE2N (ubiquitin conjugating enzyme E2 N) | protein interactions | 7334 | 208 | 52 | 17029 | 2761 |
MIB2,ZNF207,GNPNAT1,SHPRH,TRIM11,XIAP,CHIC2,CYCS,ZNRF3,NANS,SND1,PRKACA,BIRC2,CPNE3,RNF103,EPM2A,RAD23A,DTL,RFWD3,PA2G4,MDM2,VASP,DNAJC8,SIAH1,ZNRF2,RAD23B,CS,ANXA5,LRSAM1,PPA1,RNF5,LDHB,CDC5L,TNFAIP3,BIRC3,IDH3A,MRPL12,TOPORS,UBE2V1,BRCA1,TRIM28,ISG15,ARF4,RHBDF2,MFN2,DERL1,MED15,CAB39,TRIM32,GPI,CDK2,MYL12B |
| 7.069e-04 | -7.25 | FHA | smart domains | SM00240 | 23 | 10 | 9493 | 1367 |
CEP170B,AFDN,STARD9,AGGF1,FOXK1,KIF14,PPP1R8,MKI67,CHEK2,TCF19 |
| 7.076e-04 | -7.25 | MENSSEN_MYC_TARGETS | MSigDB lists | MENSSEN_MYC_TARGETS | 50 | 17 | 17377 | 2626 |
SRM,PPIF,HSPH1,LDHA,BRCA1,DNAJB1,NUTF2,CCNB1,EPRS,NSF,EFTUD2,MSH2,EI24,RUVBL2,SCARB1,MRPL3,LDHB |
| 7.078e-04 | -7.25 | ING1 (inhibitor of growth family member 1) | protein interactions | 3621 | 51 | 18 | 17029 | 2761 |
USP7,NQO1,SMARCA4,SIRT2,ARID1A,LMNA,BRMS1,PCNA,YWHAZ,KPNA2,RBBP4,YWHAH,SINHCAF,SMURF1,CDKN2A,HDAC2,SAP30,SMARCD1 |
| 7.078e-04 | -7.25 | DNMT3A (DNA methyltransferase 3 alpha) | protein interactions | 1788 | 51 | 18 | 17029 | 2761 |
USP7,MPHOSPH8,EHMT1,RTF1,UBE2I,CDC73,TRIM28,POLR2A,TERF2IP,PAF1,RB1,SP100,UHRF2,PIAS2,CTR9,PTGES3,DNMT1,CBX4 |
| 7.078e-04 | -7.25 | NT5E (5'-nucleotidase ecto) | protein interactions | 4907 | 51 | 18 | 17029 | 2761 |
RHOG,SLC41A1,CHD1L,SLC26A6,HSDL1,DNAAF5,USP22,XPO7,RFC2,USP36,PLAA,NDUFA2,ARF5,SLC44A1,TNPO2,AFF1,ACTB,NR2F2 |
| 7.082e-04 | -7.25 | MDM4 (MDM4, p53 regulator) | protein interactions | 4194 | 72 | 23 | 17029 | 2761 |
UBE2D3,USP7,RPS15,PRKAA1,EIF2AK4,ARF1,USP22,CSNK1A1,APP,RAD54B,RPL37,RB1,PSMD2,MDM2,CAPN7,E2F1,YWHAZ,BCL2,CHEK2,LRSAM1,YWHAH,SMAD4,CDKN2A |
| 7.082e-04 | -7.25 | NUP93 (nucleoporin 93) | protein interactions | 9688 | 72 | 23 | 17029 | 2761 |
NDC1,NUP188,PHB2,SUZ12,RAE1,CUL3,KRAS,BRCA1,ADRB2,UBE2I,KCMF1,NUP205,NEK6,NUP107,NUP62,NUP153,XRCC3,CLN3,NUP58,MTPN,IFI16,SEH1L,CDC5L |
| 7.082e-04 | -7.25 | TNRC6B (trinucleotide repeat containing 6B) | protein interactions | 23112 | 72 | 23 | 17029 | 2761 |
UBQLN4,AGO2,CUL3,CUL1,NUP155,BRCA1,CNTROB,TRIM65,CNOT3,CAND1,FBRS,FLAD1,CEP104,CSK,CENPJ,ODF2,GTSE1,CNOT6,CEP63,CNOT6L,SASS6,PABPC1,CARM1 |
| 7.082e-04 | -7.25 | CORO1B (coronin 1B) | protein interactions | 57175 | 72 | 23 | 17029 | 2761 |
TXNL1,TELO2,ACTR3,MYH9,CAPZA2,ANLN,TARS,PAPOLA,RAD23A,TBC1D17,CORO1C,SAFB,RAD23B,MYO18A,NUP107,ACTB,ZRANB2,KPNA2,CORO1A,RUVBL2,TERF1,DDB1,NUDC |
| 7.111e-04 | -7.25 | GSE45365_WT_VS_IFNAR_KO_BCELL_UP | MSigDB lists | GSE45365_WT_VS_IFNAR_KO_BCELL_UP | 160 | 40 | 17377 | 2626 |
CCDC93,ZNF786,SART1,CDC40,C1orf112,SESTD1,CAST,UBE2Z,KIF23,ORC1,C2orf49,PSEN1,VAV1,PSMD1,CDC42,ARL6IP1,CLDND1,HDHD2,FTSJ3,PDPK1,PLK1,BAZ2A,POLK,MAPKAPK3,KIAA0930,EZR,EMP3,ABHD11,BUD13,API5,ZFR,TAF2,NUCB1,KIF18A,HIPK2,SETD3,HPS5,ARAP1,VPS4A,ZNF75A |
| 7.125e-04 | -7.25 | TTC9C (tetratricopeptide repeat domain 9C) | protein interactions | 283237 | 43 | 16 | 17029 | 2761 |
UBQLN4,UFC1,CDK13,UBE2V1,UBE4B,CSNK1A1,MAPK3,SRXN1,GOLGA2,PPM1G,ZRANB2,TTLL12,AHCYL1,UBE2C,SSSCA1,CDC37 |
| 7.125e-04 | -7.25 | Bub1b (BUB1B, mitotic checkpoint serine/threonine kinase) | protein interactions | 12236 | 43 | 16 | 17029 | 2761 |
GOLIM4,REPS2,CDCA3,ASAH1,ANAPC2,NUF2,CDC23,MIS12,GOLM1,CDC16,CDC27,DSN1,IARS2,ANAPC7,ZMAT3,ANAPC4 |
| 7.125e-04 | -7.25 | NEPRO (nucleolus and neural progenitor protein) | protein interactions | 25871 | 43 | 16 | 17029 | 2761 |
RPP25,RPLP2,ZNF512,MECP2,RPL27A,APP,TIMM13,ATP1A1,NAP1L1,ATP2A2,POP7,PPM1G,YBX1,TFG,GPATCH4,LDHB |
| 7.125e-04 | -7.25 | MRPL20 (mitochondrial ribosomal protein L20) | protein interactions | 55052 | 43 | 16 | 17029 | 2761 |
MRPL9,CYLD,MRPL42,MRPL39,MRPL12,MRPL43,ILF3,RHOT2,APP,RCC1L,SDHB,MRPL50,CALM2,TP53BP2,MRPL21,USP13 |
| 7.145e-04 | -7.24 | GSE4748_CTRL_VS_CYANOBACTERIUM_LPSLIKE_STIM_DC_3H_DN | MSigDB lists | GSE4748_CTRL_VS_CYANOBACTERIUM_LPSLIKE_STIM_DC_3H_DN | 191 | 46 | 17377 | 2626 |
MIF,GALK1,DNAJC2,IMMT,SKA3,NOP2,NDUFB6,NIT2,GTF3A,BCL2L1,MAD2L2,FASTKD3,RNF121,PSMD1,EIF2S2,TIMM23,NAA50,ANXA5,YIF1B,RPN2,TOP1MT,MRPL11,TTLL12,METTL1,PLK3,ADAM17,TSTA3,EID1,POLK,IDH3A,TSPAN31,WDR18,ADSL,UHRF1BP1,AURKB,MRPS14,CHCHD3,PWWP2B,BOLA3,CCDC86,RBMS1,ADAM9,ACAT1,NAA20,GCSH,IPO4 |
| 7.145e-04 | -7.24 | GSE19888_CTRL_VS_T_CELL_MEMBRANES_ACT_MAST_CELL_UP | MSigDB lists | GSE19888_CTRL_VS_T_CELL_MEMBRANES_ACT_MAST_CELL_UP | 191 | 46 | 17377 | 2626 |
YTHDC2,ALKBH5,CUL1,SLC29A1,POMP,PITHD1,METTL3,TTF1,PHC2,FBXO3,UBA5,COPS7B,C8orf59,PLCL2,TOP1MT,RBM15,NDUFA3,ABI1,NAA35,ARL5A,NUP85,TMBIM1,TACC3,CPNE1,AMPD2,PDPK1,STAU1,UBQLN4,RHOA,HARS,PSPC1,MRS2,CIRBP,ADSL,DCTD,DCLRE1C,GEMIN5,BRD2,RBMX,COX5A,WIPI2,CLN3,FAU,SLC25A39,ZC3HAV1,ALS2 |
| 7.145e-04 | -7.24 | GSE27092_WT_VS_HDAC7_PHOSPHO_DEFICIENT_CD8_TCELL_DN | MSigDB lists | GSE27092_WT_VS_HDAC7_PHOSPHO_DEFICIENT_CD8_TCELL_DN | 191 | 46 | 17377 | 2626 |
IER2,VAV2,LACTB2,EIF1B,GGPS1,TCF19,MAP1LC3B,SYNRG,STMN1,PAPOLA,RPA2,NUDT19,ZBTB45,HOMER1,STRBP,MED10,VMP1,ZKSCAN1,MCM5,DNM2,AXIN2,GLTP,CNN2,ACSL5,SP3,LARS,SHOC2,POLR2I,NCK1,NUDT4,WIPF1,RCOR1,CDC23,ISG15,ASF1B,SRSF1,MRPL2,DAP3,ATP6V1D,HNRNPH3,TBL3,ACLY,CRCP,NDE1,COIL,S100PBP |
| 7.145e-04 | -7.24 | GSE2770_TGFB_AND_IL4_VS_TGFB_AND_IL12_TREATED_ACT_CD4_TCELL_6H_DN | MSigDB lists | GSE2770_TGFB_AND_IL4_VS_TGFB_AND_IL12_TREATED_ACT_CD4_TCELL_6H_DN | 191 | 46 | 17377 | 2626 |
PARP12,LUZP1,TSC22D3,GADD45G,XIAP,CHIC2,CREBL2,NUF2,ATP6V1B2,RAB11A,BZW2,RAPGEF6,MYEF2,RGS1,UBLCP1,SLC25A36,HNRNPA2B1,HOMER1,INTS7,RABGAP1L,DCP1A,ANP32A,RNF19A,ZNF770,SAP30,VOPP1,YTHDC1,TNFAIP3,NSUN2,TOP3A,ITM2A,MAP4K3,MCL1,HERPUD2,PHF6,ARHGAP15,TRIM26,IDE,RBL1,PDRG1,DCK,EXOC4,PIAS2,MEGF9,RBBP4,RNF14 |
| 7.145e-04 | -7.24 | GSE33374_CD8_ALPHAALPHA_VS_ALPHABETA_CD161_HIGH_TCELL_DN | MSigDB lists | GSE33374_CD8_ALPHAALPHA_VS_ALPHABETA_CD161_HIGH_TCELL_DN | 191 | 46 | 17377 | 2626 |
SEPHS2,RHOG,IER2,DDX47,PKP4,PHF23,HLA-E,DAP,TAP1,PSMD9,REPS1,BZW2,BCAP31,HLA-A,TMEM179B,FAM192A,VAV1,DECR1,MED10,EIF4A3,VMP1,DAD1,EFTUD2,RPL19,SLC38A10,METTL9,F2R,CSNK1G2,SEPT9,DENND4C,GBA,PSMB9,GOSR1,ABCF1,PSMB3,ISG15,FAS,LEMD2,PEX5,WAS,MTHFD2,EIF2D,DUSP11,PPP5C,EYA2,PFKP |
| 7.145e-04 | -7.24 | GSE17721_CPG_VS_GARDIQUIMOD_0.5H_BMDC_DN | MSigDB lists | GSE17721_CPG_VS_GARDIQUIMOD_0.5H_BMDC_DN | 191 | 46 | 17377 | 2626 |
TMEM184B,ADD1,AGRN,FAM53C,SF3B1,TAP1,TKT,BRAP,EPN1,SYNRG,RCOR3,APP,RBM17,CCNK,PELO,TNPO2,ABCD1,ANKRD13C,ANAPC7,MDFIC,RNF135,DNMT1,LYPLA2,RPAP3,SHOC2,PPP1R21,KIAA0930,MAP4K4,LRBA,RNF25,UHRF1BP1,NFATC2,NFATC2IP,MKNK1,PDCD6,GOLGA2,FBXO28,GOLGA7,COX8A,CHMP4B,DNAJC30,PTDSS1,ZNF598,MYL12B,GPATCH4,TMEM131 |
| 7.145e-04 | -7.24 | GSE23321_CENTRAL_VS_EFFECTOR_MEMORY_CD8_TCELL_UP | MSigDB lists | GSE23321_CENTRAL_VS_EFFECTOR_MEMORY_CD8_TCELL_UP | 191 | 46 | 17377 | 2626 |
ZNF207,PTMS,CDS2,TRIP12,FAM207A,SRGN,TM9SF3,UBE2Z,JMJD6,DNAJB1,SLC35B2,SND1,SAFB2,PMVK,LCLAT1,TTF1,KIF5B,NEK6,TBC1D14,PTPN11,FEM1B,RNF135,CTDSP2,GCC1,CDC5L,CYFIP1,TIMP2,ANKRD33B,CPOX,LRBA,ARHGEF12,PLEC,EDEM2,RBM38,CACNB1,GNA12,LUC7L3,NFIL3,ZNF436,ROCK1,SLC22A23,RPS6KC1,CD81,MRPL3,ALS2,TMEM131 |
| 7.161e-04 | -7.24 | nucleoside binding | molecular function | GO:0001882 | 380 | 82 | 17224 | 2647 |
RHOG,RAB14,RAB11B,RAC1,OLA1,TPX2,RRAGC,GLUD1,EFL1,MIEF1,RAB21,RAB8A,RAP1A,CDC42,SAR1A,RALB,RAB35,RAB4A,DNM2,UPRT,SEPT11,SUCLG2,RP2,EIF5,ARL5A,RHOBTB3,NRAS,SEPT9,CGAS,RAB7A,RAB1A,ARL5B,RAB5B,RAB22A,LSG1,RAB2B,ARF4,RHEB,DAP3,SEPT1,RAB24,GUCY1B1,TUBB,RHEBL1,ANXA6,RHOC,GSPT2,RAB23,ARFIP2,RAB6A,ARF1,IFT27,RAB11A,GFM2,RTKN,GTPBP3,ARF5,EFTUD2,DAPK1,POLR1B,GNAI2,RHOA,NOA1,TUFM,GTPBP4,SEPT8,BMS1,KRAS,RIT1,RHOT1,SEPT7,RHOT2,GUF1,RHOB,MFN2,GNAS,ADSS,GNA12,RAB18,PRPS2,EHD4,HRAS |
| 7.163e-04 | -7.24 | LMO7 (LIM domain 7) | protein interactions | 4008 | 47 | 17 | 17029 | 2761 |
ILF3,MYH9,RAB3IP,CAPZA2,PKM,ANLN,RPA1,RPA2,MDM2,HNRNPR,E2F4,MYO18A,ODF2,CDK2,ABCA1,SRPK2,CDC5L |
| 7.163e-04 | -7.24 | ANXA11 (annexin A11) | protein interactions | 311 | 47 | 17 | 17029 | 2761 |
MIF,EWSR1,RAC1,LDHA,TOMM40,PEF1,PCBP1,SLC25A5,PDCD6,NDUFV1,HNRNPH3,CEP55,SRI,TFG,S100A6,CDC5L,FUBP1 |
| 7.243e-04 | -7.23 | gastrointestinal_stromal_tumour | COSMIC cancer mutations | gastrointestinal_stromal_tumour | 78 | 23 | 17385 | 2587 |
ERMP1,NRAS,NCK1,NF1,SF3B1,KRAS,MAP2K2,DAPK3,GNAS,FGFR3,RB1,SGSH,PTEN,PTPN11,TIMELESS,FUS,H3F3A,CLN3,STAT3,PGAM1,HRAS,CDKN2A,ABCC5 |
| 7.250e-04 | -7.23 | 4-hydroxytamoxifen, Dexamethasone, and Retinoic Acids Regulation of p27 Expression | WikiPathways | WP3879 | 18 | 9 | 5312 | 837 |
TSC1,MKNK1,MAP3K5,MAPK1,RAF1,MAP2K2,PBK,PRKAA1,MAPK3 |
| 7.268e-04 | -7.23 | telomeric DNA binding | molecular function | GO:0042162 | 37 | 14 | 17224 | 2647 |
TERF2IP,HNRNPA2B1,RPA2,TELO2,UPF1,NABP2,UPF2,BLM,POT1,PURA,TERF1,TERF2,XRCC5,RPA1 |
| 7.277e-04 | -7.23 | Sema4D induced cell migration and growth-cone collapse | REACTOME pathways | R-HSA-416572 | 24 | 11 | 10287 | 1696 |
RHOG,RHOA,CDC42,LIMK1,RHOC,RAC1,MYH9,ARHGEF12,ROCK1,MYL12B,RHOB |
| 7.280e-04 | -7.23 | GSE4984_GALECTIN1_VS_LPS_STIM_DC_UP | MSigDB lists | GSE4984_GALECTIN1_VS_LPS_STIM_DC_UP | 150 | 38 | 17377 | 2626 |
DDX58,RHOG,ABCA3,BRAP,MYH9,SLC4A2,ELMOD2,ZER1,ATP6V0B,VASP,ACAD8,TRIM14,DRAM2,KDELR1,VPS13B,PPP1R9B,CYTH1,TIMP2,RDH10,MFNG,POLR3GL,MTMR12,ARID1A,POLG2,PLEKHF2,MTMR3,NSA2,SLCO4A1,VEZF1,PEX5,ARAP1,RNF38,ARRDC1,MBD6,NCOA1,TFDP2,IGBP1,LONP2 |
| 7.284e-04 | -7.22 | GO_RESPONSE_TO_UV | MSigDB lists | GO_RESPONSE_TO_UV | 120 | 32 | 17377 | 2626 |
BAK1,ERCC1,PBK,PRKAA1,CIRBP,MAP4K3,AURKB,UBE4B,EIF2AK4,MEN1,RPAIN,RHBDD1,DTL,MAP3K4,CAT,USF1,MDM2,PCNA,RAD18,XPA,PML,NOC2L,MSH2,BCL2,STK11,TRIM32,RUVBL2,YY1,GTF2H2,MSH6,DDB1,PTPRK |
| 7.306e-04 | -7.22 | host | cellular component | GO:0018995 | 69 | 21 | 18223 | 2701 |
NDC1,NUP188,RAE1,NUP54,NUP155,NUP205,NMT2,PI4K2A,KPNA4,NUP210,KPNA1,RPS27A,NUP107,NUP153,NUP62,KPNA2,LMAN1,NUP85,NUP58,AAAS,SEH1L |
| 7.306e-04 | -7.22 | host cell | cellular component | GO:0043657 | 69 | 21 | 18223 | 2701 |
NDC1,NUP188,RAE1,NUP54,NUP155,NMT2,NUP205,PI4K2A,NUP210,KPNA1,KPNA4,RPS27A,NUP107,NUP62,KPNA2,NUP153,LMAN1,NUP58,NUP85,AAAS,SEH1L |
| 7.319e-04 | -7.22 | MODULE_182 | MSigDB lists | MODULE_182 | 91 | 26 | 17377 | 2626 |
FYTTD1,SNRNP200,NRAS,KLF10,MIOS,TACC1,NSUN2,DBF4,SLC25A22,DCLRE1C,RLF,SEC16A,SCYL2,DHX15,NUP205,CRKL,MDM2,INTS7,SEC24C,KLHL15,PTPN11,AEN,GLCCI1,PURA,NMD3,MICAL3 |
| 7.323e-04 | -7.22 | BERTUCCI_MEDULLARY_VS_DUCTAL_BREAST_CANCER_UP | MSigDB lists | BERTUCCI_MEDULLARY_VS_DUCTAL_BREAST_CANCER_UP | 186 | 45 | 17377 | 2626 |
ABCA3,NSMCE4A,MCM10,ZCCHC9,NOP2,FOXM1,PHB2,PPP1R15B,SRGN,CDCA3,TAP1,BTN3A1,MYNN,GYG1,RGS1,ASPHD2,CTSS,ETV6,GTSE1,PLCL2,MINPP1,FBL,MCMBP,PPA1,ACSL5,PPIF,LARS,TRAFD1,BIRC3,LAP3,MKI67,DNAJC9,IL12RB1,PSMB9,EPB41,HSPA4,SEC23IP,CHCHD1,CEP55,PQBP1,STAT1,SIAH2,CCDC69,TCOF1,PSAP |
| 7.323e-04 | -7.22 | GSE32423_IL7_VS_IL7_IL4_MEMORY_CD8_TCELL_DN | MSigDB lists | GSE32423_IL7_VS_IL7_IL4_MEMORY_CD8_TCELL_DN | 186 | 45 | 17377 | 2626 |
POLA2,TRAF7,CXXC1,TAP1,ARID5A,LAGE3,INO80E,AP1B1,FZD6,WWP2,IRF4,ERH,EIF4A3,TBC1D22A,KIF14,PPME1,ANP32A,ORAI1,LTN1,MRPL40,APOOL,TGFB1,TRAPPC9,ANKRD33B,MRS2,CKAP2L,ADSL,IL12RB1,MEN1,TXNL4A,TRIM28,CYB5A,GEMIN5,BOLA3,ZNF777,SERF2,TBL3,NFIL3,AP1S1,ACAT1,NUP62,ASNA1,NANP,CHPF2,LRP8 |
| 7.323e-04 | -7.22 | GSE3982_DC_VS_TH1_DN | MSigDB lists | GSE3982_DC_VS_TH1_DN | 186 | 45 | 17377 | 2626 |
FGFR1OP,CYLD,HNRNPAB,PTTG1,CENPF,RRM1,CTCF,PXMP2,KIF2C,ORC1,SNRPD3,PPP1R16B,MXD1,CFLAR,CREM,SRSF4,PELO,TXLNA,BRD7,BCL2,PRPF19,NASP,HARS,PGS1,PBK,LDB1,DNAJC9,EXOSC9,GLO1,EAF2,KLF6,GINS4,SUPT16H,MBIP,CDCA4,ATAD2,BIRC5,NIP7,TFDP1,FTSJ1,QRSL1,PRMT7,CCNB2,FUBP1,POLQ |
| 7.323e-04 | -7.22 | GSE36078_WT_VS_IL1R_KO_LUNG_DC_AFTER_AD5_T425A_HEXON_INF_UP | MSigDB lists | GSE36078_WT_VS_IL1R_KO_LUNG_DC_AFTER_AD5_T425A_HEXON_INF_UP | 186 | 45 | 17377 | 2626 |
SEPHS2,MMACHC,ANXA6,PPP1R12A,DCAF15,TMEM41B,BABAM1,NUP54,B4GALT1,SIKE1,SIRT2,SDF2L1,CMTM6,TUBGCP2,WRNIP1,PRKD3,MDM2,WDR44,UCHL5,BANF1,MDFIC,LMAN1,GNAI2,TMEM14C,ARL5A,TMBIM1,TSHZ1,SP3,PPP1R18,HELB,MKI67,RRM2,CKAP2L,LRRC8A,IL12RB1,BRCA1,AMDHD2,CCNF,BORA,MYO1F,SDHB,NUCB1,COX5A,RBPJ,CBX4 |
| 7.323e-04 | -7.22 | GSE17721_4H_VS_24H_POLYIC_BMDC_DN | MSigDB lists | GSE17721_4H_VS_24H_POLYIC_BMDC_DN | 186 | 45 | 17377 | 2626 |
BCCIP,TCF12,TM9SF4,PRKCSH,CDT1,DCTN2,CERK,SUMF1,PRPF39,LYRM2,APP,CNOT3,BUD31,PPCDC,ANAPC7,METTL9,AHCYL1,PACS2,TMBIM1,SRSF11,CSNK1G2,FTL,BRD4,TRIM8,TSTA3,HELB,TYW1,METTL5,GBA,TUBGCP5,LACTB,WBP2,PSMA1,PFKFB3,WBP1,IL12RB1,DHX57,SUGP1,TULP3,OAZ2,PRDX5,SAMD8,SSNA1,TRIM32,NAA60 |
| 7.323e-04 | -7.22 | GSE17721_0.5H_VS_12H_POLYIC_BMDC_UP | MSigDB lists | GSE17721_0.5H_VS_12H_POLYIC_BMDC_UP | 186 | 45 | 17377 | 2626 |
NSMCE4A,MRPS15,GNPDA1,BABAM1,SEC16A,PRKACA,MIEN1,TUBGCP2,PIP4K2A,CCDC28A,TFRC,PABPC4,EBP,GSTK1,RAP1A,STRBP,DAD1,BDH1,XPA,POP7,TTC4,ALDH18A1,PTPN18,CELSR2,KLF10,RBX1,NOA1,ERLIN1,TIGD5,USP10,ARHGDIB,KRTCAP2,FANCE,CHCHD6,SLC50A1,CLNS1A,STOML2,DNAJC10,ACOX1,LIMK1,KLHDC4,PDXK,SNRNP70,AP2S1,MRPL3 |
| 7.323e-04 | -7.22 | GSE23568_ID3_TRANSDUCED_VS_ID3_KO_CD8_TCELL_DN | MSigDB lists | GSE23568_ID3_TRANSDUCED_VS_ID3_KO_CD8_TCELL_DN | 186 | 45 | 17377 | 2626 |
CYTIP,ANKH,TAP1,CDC42SE2,EZH1,ETS1,DNAJB9,CFLAR,SLC25A36,RRN3,MLX,INPP5A,ARPC5,AKAP8,ARHGEF1,SLC44A1,GLTP,TTC17,FRMD8,ABCC5,CYFIP1,SNX2,CIC,WDR1,ITM2A,MCL1,PSMB9,LUC7L,EIF4G2,MATR3,FAS,HLA-B,ATP6V1D,AHNAK,ATP1A1,RBM25,PPP2R5A,SAFB,OGT,ITGB1,GALNT10,DVL1,TRAF5,SMAD4,TOB1 |
| 7.327e-04 | -7.22 | negative regulation of macromolecule metabolic process | biological process | GO:0010605 | 2744 | 473 | 17256 | 2622 |
FGFR1OP,TXN,ZNF496,MAX,H2AFZ,TSC2,KDM4A,TSC22D3,XIAP,YTHDF3,CCNB1,UBE2I,PPP1R16B,RBM4,RIC1,PARK7,RPL23A,CALM2,CDK5,CDKN2C,PA2G4,CIPC,PARPBP,SRSF4,TRA2B,CRY2,FNIP2,SMARCE1,TIPARP,DNMT1,SENP1,SRSF10,BAK1,PLK3,ERCC1,KLF10,AATF,GABPA,PBK,EHMT1,DDX20,AURKB,EIF3A,DOT1L,BRMS1,HHEX,SMAD2,RPS27A,RPS14,LIMK1,AXIN1,PRDX5,OGT,SMG9,TFDP2,SMAD1,ARRB2,HDAC2,PDCD4,SVIP,HSPH1,GMFG,GSPT2,PRKAA1,DHX9,EIF2AK4,NOTCH2,PARN,PSEN1,METTL3,VPS25,CDC73,CNOT3,CFLAR,DDRGK1,TFAP4,CD59,FKBP1A,SMC3,EXOSC7,MEX3C,KLF16,HDAC7,FBXO7,PHF14,MSH2,DAPK1,MVP,GNAI2,TNRC18,PABPC1,TERF2,SOCS5,RBM42,ETV3,FOXK1,ZMYND11,MTA2,GTPBP4,RPS10,ITM2A,RPS24,BCLAF1,EXOSC9,ARID1A,CBFA2T2,FXR1,KDM3A,PATL1,MAP2K2,PHF6,XRCC5,EPRS,PFDN5,ETS2,DUSP3,CSK,RBMX,QARS,CABIN1,CNOT6,YY1,ZNF830,CDK2,RNF139,CDKN2A,ZNF296,PPP1R37,DNMT3A,GGNBP2,RPS6KA1,UBR2,SUZ12,CAST,RAF1,PTTG1,MAGED1,WDTC1,RCOR3,APP,PAIP2,TERF2IP,SPINDOC,APLP2,SHC1,SP100,MTA1,UCHL5,SOCS6,CDKN1B,RBM15,ATF2,GPD1L,CGGBP1,PDCL3,RNF169,SAP30,CPNE1,ERF,EID1,DRAP1,RPL38,RNPS1,POLR2D,CUL3,CIRBP,DNAJA1,H2AFV,TRIM28,DDX17,SOCS7,PPP2CA,CHCHD3,ZNF282,DGCR8,LSM6,CORO1C,HIPK2,NT5C3B,H2AFX,RPLP1,STAT1,BEND3,PPP5C,LRP8,POLQ,POU3F2,NCOR2,RPS2,DEPDC1,SRSF6,MECP2,TCF3,SECISBP2,AKT1S1,BLM,HMG20A,FOXO3,MAD2L2,TUT4,WWP2,PDCD10,ITGB8,SUV39H2,RPL17,PTEN,PPP1R8,AXIN2,DCP1A,RPL19,UPF2,CITED2,CNOT6L,CREB1,NCOA2,MSH6,TSHZ1,PDPK1,PPP3CA,TNFAIP3,RPL8,ILF3,KCNQ1,ZP3,RPL27A,PICALM,CBX3,SH3BP5,RPL32,GPS2,ZHX1,PRDX3,PITX1,LRPPRC,PML,KHSRP,PPP1R11,DDX5,HMGB2,PARP10,IGBP1,CPEB2,PURA,RORB,ZBED3,THOC1,NF1,TRIM11,PPP1R15B,FAM129A,RBM8A,ENSA,CSNK2A1,SND1,SIRT2,UBQLN2,MAPK14,BIRC2,EDC3,CREM,PRNP,CYREN,GLIS2,EIF4A3,ZNF639,METTL14,JAZF1,ETV6,PIK3R2,NOC2L,SLC35C2,OGG1,ARID4A,CCAR1,PTPRK,RYBP,PLK1,SP3,DEAF1,EXOSC6,PBXIP1,NCK1,BAZ2A,VHL,RIOX2,GMFB,EZR,CDC6,LRP5,BRCA1,SOX4,PRKRA,OPTN,RPL37,PAF1,EIF4ENIF1,TONSL,SOCS4,ZNF268,CHEK2,CLU,ROCK1,DVL1,CLN3,BEND6,RPS26,POT1,ZNF564,UBE2D3,RPS15,PPP1R2,PHB2,CENPF,UBXN1,CIB1,CTCF,TIA1,RPL15,MEF2A,DNAJB1,THRAP3,RGS2,CNOT11,TTF1,SRRT,PRPF18,LYAR,RB1,MLX,NFATC3,MBD2,ZNF746,ARL6IP1,CTR9,TIMELESS,MDFIC,YBX1,MCPH1,ZNF189,CREG1,CIC,OXR1,LDB1,RPL6,GBA,EIF2AK1,RTF1,DAPK3,ISG15,ZNF174,MASTL,RPL36,TSC1,MBIP,SYNCRIP,KLHL15,NFIL3,SIAH2,NUP62,CTSA,ZFP90,RUVBL2,RBBP4,SNRNP70,TOB1,N4BP2L2,USP7,MBD1,ASH1L,RPLP2,MPHOSPH8,FOXM1,SMARCA4,IRF3,LYN,DUSP22,MXD1,PAIP1,RPL11,HNRNPA2B1,SAP130,CSDE1,ZBTB21,MDM2,TNFAIP8,PIN1,PPME1,EXOSC1,TARDBP,STRAP,CTDSP2,RLIM,MOSPD1,CHP1,SNX25,RPL29,TIMP2,RPL35,BIRC3,POLR2G,FAM172A,ZNF500,PGGT1B,BTG2,PCGF6,ATXN1,NFATC2,MBD3,RPS9,RPSA,DNAJC10,IDE,RBL1,HNRNPR,MAFK,STAT6,STK38,GADD45B,ARNTL,DNAJC17,H3F3A,SMAD4,CBX4,PARD3,BCL2L12,MIF,DNAJC2,UNK,TRIP12,DAP,AGO2,ARID5A,PAWR,NKRF,MXD4,FBXO5,PTPN2,KMT5A,PELO,DUS2,H2AFY,BRD7,STAT3,RBM15B,TGFB1,SAMD4B,PPP1R9B,BTAF1,PSPC1,ZNF202,PRKDC,HELB,PRKAR1B,RFFL,RCOR1,PRMT2,MEN1,HSPA1B,CNOT9,LEMD2,UPF1,PLAA,BIRC5,ZC3H7B,E2F1,GLG1,KMT2B,RBPJ,NR2F2,HRAS,HIPK3,TERF1,IFI16 |
| 7.331e-04 | -7.22 | ICAM1 (intercellular adhesion molecule 1) | protein interactions | 3383 | 174 | 45 | 17029 | 2761 |
RPS15,RPS2,RPLP2,CSNK2A1,SNRPD3,AP3S1,GIT2,RPL11,RPL23A,HNRNPA2B1,CLIC4,RPL17,YBX1,RPL19,PABPC1,EIF3L,RPL35,FAM118B,SNRPB,RPL6,RPL8,ILF3,EZR,RPL27A,RPS9,EIF3G,EIF3A,EIF3H,SUPT16H,DDX17,RPL36,XRCC5,EIF3K,SYNCRIP,RPS14,DHTKD1,CBWD1,ACTB,TCOF1,SRSF3,FAU,MZT2B,PURA,TUBB,IFI16 |
| 7.367e-04 | -7.21 | RAS signaling downstream of NF1 loss-of-function variants | REACTOME pathways | R-HSA-6802953 | 4 | 4 | 10287 | 1696 |
KRAS,NRAS,NF1,HRAS |
| 7.395e-04 | -7.21 | WILCOX_RESPONSE_TO_PROGESTERONE_UP | MSigDB lists | WILCOX_RESPONSE_TO_PROGESTERONE_UP | 135 | 35 | 17377 | 2626 |
HJURP,CENPF,YTHDC2,TMEM97,HMGN3,ATG2B,CCNB1,RGS2,ZNF518A,NCAPG,DNAJB9,FANCI,EBP,CDKN2C,DNAAF2,PRC1,FDFT1,CDKN2AIP,TK1,ASPM,NSDHL,PBK,RRM2,WDHD1,CDC6,NUSAP1,SMC2,GALK2,KLF6,SHCBP1,CEP55,ZNF268,HMGB2,XRCC4,CCNB2 |
| 7.451e-04 | -7.20 | Znf_RING | interpro domains | IPR001841 | 290 | 64 | 18492 | 2768 |
MIB2,TRIM41,TRAF7,PHRF1,TRIM11,XIAP,RUFY1,TRIM65,BIRC2,ANKIB1,RNF103,CYHR1,MDM2,SIAH1,TTC3,RNF19A,RNF26,RNF169,RLIM,TRIM8,BIRC3,RBX1,RNF25,PCGF6,LNX2,TOPORS,BRCA1,KMT2C,TRIM28,TRIM4,TRIM47,RAD18,RNF38,UHRF2,BAZ1B,TRIM32,TRIM52,TRAF5,ZNF598,SHPRH,CBLL1,BRAP,ZNRF3,RFWD3,RNF121,MEX3C,RNFT1,ZNRF2,LTN1,RNF135,LRSAM1,RNF5,LONRF3,RFFL,SYVN1,PCGF1,COMMD3-BMI1,TRIM26,PML,SIAH2,DTX4,RNF14,RNF139,RNF114 |
| 7.478e-04 | -7.20 | DURCHDEWALD_SKIN_CARCINOGENESIS_DN | MSigDB lists | DURCHDEWALD_SKIN_CARCINOGENESIS_DN | 255 | 58 | 17377 | 2626 |
UBL3,COMMD10,CDC40,CAST,DAP,ANK3,UCK2,TMX3,MYH9,LETMD1,B4GALT1,SNN,GIT2,MXD1,NPLOC4,LIN9,KIF5B,APLP2,UBE2Q2,NVL,RALB,ATP13A3,LTN1,TIPARP,GM2A,ABCC1,ELL2,C16orf72,NET1,NSDHL,MAP4K4,TAOK1,ATP2C1,GBA,CADM1,ODC1,MACF1,KLF6,RAB22A,CAT,MAGED2,RBM25,TATDN2,ACOX1,MAFK,MAPK6,ITGB1,RNF38,ZNF436,YWHAZ,MBOAT1,RBBP4,BTBD10,SMURF1,LRP8,HIPK3,FAM83G,PRPF4B |
| 7.496e-04 | -7.20 | GSE32423_MEMORY_VS_NAIVE_CD8_TCELL_IL7_IL4_DN | MSigDB lists | GSE32423_MEMORY_VS_NAIVE_CD8_TCELL_IL7_IL4_DN | 181 | 44 | 17377 | 2626 |
MIF4GD,FAM208B,CHD1L,AGFG1,DNAJB1,GGA2,RCOR3,XPR1,ANKRD28,TERF2IP,RFWD3,ANKRD26,HOMER1,STRBP,TTC9C,GLE1,NAA35,TMED2,FYTTD1,SNX25,TDP1,CDKN2AIP,RPRD1A,GABPA,BTAF1,KIAA0930,RNPS1,MAP4K3,BCLAF1,SMC2,PAF1,PTPRF,ZNF282,PLAA,TMEM168,DSN1,OSBPL8,LUC7L3,BBX,PTAR1,VPS4A,YY1,PITRM1,CDK2 |
| 7.496e-04 | -7.20 | GSE46606_IRF4MID_VS_WT_CD40L_IL2_IL5_DAY1_STIMULATED_BCELL_UP | MSigDB lists | GSE46606_IRF4MID_VS_WT_CD40L_IL2_IL5_DAY1_STIMULATED_BCELL_UP | 181 | 44 | 17377 | 2626 |
CCDC93,TCF12,ANKRD13D,PLXNC1,TSC22D3,CDT1,MRPS26,LAGE3,KLF13,RGS2,FOXO3,ZBTB45,STRBP,ZKSCAN1,MSH2,DDX31,FNIP2,METTL9,GINS1,KAT2A,MAPKAPK3,TSPYL4,DENND4C,MBLAC2,KIAA0930,RPS10,POLG2,BORA,HAGH,GIGYF1,CBX3,RPA1,SDHB,FBXO21,PWWP2B,APPL2,BAZ1B,ARRDC1,PDXK,TMEM14A,GEN1,SLC25A39,ATMIN,PDCD4 |
| 7.496e-04 | -7.20 | GSE36392_MAC_VS_NEUTROPHIL_IL25_TREATED_LUNG_UP | MSigDB lists | GSE36392_MAC_VS_NEUTROPHIL_IL25_TREATED_LUNG_UP | 181 | 44 | 17377 | 2626 |
ANXA6,DLGAP4,KLC1,SUMF1,CREBL2,ABCB10,ARGLU1,LANCL1,MXD4,B4GALT4,PITHD1,TRIM65,RPL23A,ARHGEF1,GEMIN6,RPAP1,UPF2,SS18L1,ZNF710,CITED2,SLC35C2,LDLRAD3,CTDSP2,KDM3B,JMJD4,TSPYL4,EID1,TACC1,MRPL16,ICAM2,ASB13,FXR1,MARK2,SRSF1,ZNF862,DHX16,PDRG1,HIPK2,ZDHHC7,MBD6,AKNA,RPS26,SSSCA1,RNF114 |
| 7.521e-04 | -7.19 | RDX (radixin) | protein interactions | 5962 | 81 | 25 | 17029 | 2761 |
CPNE1,HSPH1,SNX2,GSPT2,TRMT6,NSUN2,MRPL12,TKT,HNRNPF,EZR,BRCA1,NOTCH2,ICAM2,LYN,BCAP31,TSC1,HSPA4,BRWD1,AKR1B1,ANP32E,TAGLN2,ROCK1,ATP6V1C1,PPA1,IMPA2 |
| 7.538e-04 | -7.19 | DNA Double-Strand Break Repair | REACTOME pathways | R-HSA-5693532 | 167 | 44 | 10287 | 1696 |
CLSPN,KDM4A,EYA1,SUMO2,BABAM1,RMI2,BLM,UBE2I,RMI1,RPA2,PCNA,BABAM2,CCNA2,XRCC2,TIMELESS,SPIDR,TDP1,ERCC1,RFC3,POLK,RAD51AP1,PRKDC,TOP3A,BRCA1,DCLRE1C,RFC2,RPA1,XRCC5,RAD51C,PALB2,POLE,RPS27A,H2AFX,BAZ1B,XRCC3,KPNA2,CHEK2,PPP5C,CDK2,GEN1,XRCC4,EYA2,RAD51D,POLQ |
| 7.541e-04 | -7.19 | cellular response to nerve growth factor stimulus | biological process | GO:1990090 | 50 | 17 | 17256 | 2622 |
PDPK1,KAT2A,CIB1,RPL8,FOXO3,APP,EEF2K,RAP1A,EIF4A3,PTEN,RAB35,E2F1,CORO1A,CREB1,CSNK1D,DYNC1LI2,CDC5L |
| 7.541e-04 | -7.19 | cortical cytoskeleton organization | biological process | GO:0030865 | 50 | 17 | 17256 | 2622 |
RHOBTB3,PDCD6IP,STRIP1,WDR1,WIPF1,KIF23,EZR,RACGAP1,NCKAP1,ANLN,RTKN,EPB41,CDK5,WAS,CDC42,ROCK1,VPS4A |
| 7.544e-04 | -7.19 | Ribosome, eukaryotes | KEGG pathways | M00177 | 91 | 27 | 7161 | 1149 |
RPS15,RPL29,RPL35,RPS2,RPLP2,RPL8,RPS10,RPL6,RPL38,RPL15,RPS24,RPL27A,RPS9,RPSA,RPL11,RPL23A,RPL36,RPL37,RPL32,RPL17,RPS27A,RPS14,RPLP1,RPL19,FAU,RPS26,RPL22L1 |
| 7.544e-04 | -7.19 | Ribosome, eukaryotes | KEGG pathways | hsa_M00177 | 91 | 27 | 7161 | 1149 |
RPS15,RPL29,RPL35,RPS2,RPLP2,RPL8,RPS10,RPL6,RPL38,RPL15,RPS24,RPL27A,RPS9,RPSA,RPL11,RPL23A,RPL36,RPL37,RPL32,RPL17,RPS27A,RPS14,RPLP1,RPL19,FAU,RPS26,RPL22L1 |
| 7.563e-04 | -7.19 | HIPK2 (homeodomain interacting protein kinase 2) | protein interactions | 28996 | 68 | 22 | 17029 | 2761 |
AATF,MECP2,SUMO2,MYBL2,CUL1,UBE2I,DDX39A,FBXO3,MKNK1,MDM2,SMAD2,SP100,SIAH1,AXIN1,HIPK2,SIAH2,PML,CHMP4B,SMAD1,MYBL1,SENP1,CBX4 |
| 7.563e-04 | -7.19 | FYTTD1 (forty-two-three domain containing 1) | protein interactions | 84248 | 68 | 22 | 17029 | 2761 |
NOL12,FYTTD1,SARNP,THOC1,SUZ12,GNG7,RPL6,PMVK,CYB5A,SUPT16H,FERMT3,EIF4A3,ANP32E,RNASEH2A,CHTOP,NKAPD1,C12orf75,XRCC4,STRAP,TUBB,SSSCA1,SSRP1 |
| 7.563e-04 | -7.19 | MCL1 (MCL1, BCL2 family apoptosis regulator) | protein interactions | 4170 | 68 | 22 | 17029 | 2761 |
BAK1,UNK,PRKAB1,TRIM11,PRKAA1,AGO2,CUL1,MCL1,BCL2L1,VDAC1,EDEM2,DUSP22,LYN,BECN1,STARD9,PCNA,HSPA4,HUWE1,DAD1,PIN1,UHRF2,MAPK1 |
| 7.566e-04 | -7.19 | CAPZB (capping actin protein of muscle Z-line subunit beta) | protein interactions | 832 | 108 | 31 | 17029 | 2761 |
RPAP3,BCCIP,ARHGAP17,COX15,VHL,DCTN2,MYH9,BRCA1,CAPZA2,TOMM40,MCFD2,ANLN,MCM2,TWF2,MARK2,CDC73,UBE2Q2,EIF4A3,ARPC5,HUWE1,MYO18A,RCSD1,DAPK1,CAPZA1,AHCY,DMWD,CDK2,HEXA,CARMIL1,MTPN,DCTN1 |
| 7.566e-04 | -7.19 | ATP5PB (ATP synthase peripheral stalk-membrane subunit b) | protein interactions | 515 | 108 | 31 | 17029 | 2761 |
ATP5IF1,RPS2,TOMM20,NDUFS1,MRPL42,VDAC2,CHCHD2,NDUFA4,ATP5F1B,FAM136A,MCM2,VDAC1,ATP5PF,RCOR3,SDHA,NDUFS7,NDUFS4,STOML2,ZMYM3,NDUFV1,TXNDC16,CERS6,ZFYVE27,ATP6V0A2,NDUFB9,MRPL40,ATP5F1A,LMAN1,B4GALT3,CDK2,ATP6V0D1 |
| 7.580e-04 | -7.18 | MODULE_337 | MSigDB lists | MODULE_337 | 59 | 19 | 17377 | 2626 |
CENPF,ILF3,UCK2,RRM1,RRM2,ADSL,NUP155,ORC1,SNRPA,SLC25A37,NUP205,SAC3D1,ALG3,UTP18,PRPS2,E2F1,ACLY,HDAC2,BYSL |
| 7.580e-04 | -7.18 | ACAWNRNSRCGG_UNKNOWN | MSigDB lists | ACAWNRNSRCGG_UNKNOWN | 59 | 19 | 17377 | 2626 |
ELOVL5,PRPF38B,CXXC1,ILF3,CTCF,UBE4B,ARF1,EIF4G2,FKBP3,RXRB,DDX17,CRKL,MTMR3,AKAP8,TRA2B,DDX5,RBM3,SRSF3,RNF26 |
| 7.588e-04 | -7.18 | BOHN_PRIMARY_IMMUNODEFICIENCY_SYNDROM_UP | MSigDB lists | BOHN_PRIMARY_IMMUNODEFICIENCY_SYNDROM_UP | 46 | 16 | 17377 | 2626 |
MLEC,TXN,ASPM,SELPLG,MKI67,SSR2,NUSAP1,SMC2,BLM,OAT,RPSA,CDKN1B,TAGLN2,SRSF3,UBE2C,NMD3 |
| 7.588e-04 | -7.18 | REACTOME_CDK_MEDIATED_PHOSPHORYLATION_AND_REMOVAL_OF_CDC6 | MSigDB lists | REACTOME_CDK_MEDIATED_PHOSPHORYLATION_AND_REMOVAL_OF_CDC6 | 46 | 16 | 17377 | 2626 |
PSMD2,PSMD1,PSMA6,PSMA8,RPS27A,PSMD8,PSMD3,PSMB7,PSMA1,CDC6,PSMB9,CDK2,PSMD9,PSMC1,PSMB3,PSMC4 |
| 7.588e-04 | -7.18 | KEGG_N_GLYCAN_BIOSYNTHESIS | MSigDB lists | KEGG_N_GLYCAN_BIOSYNTHESIS | 46 | 16 | 17377 | 2626 |
MAN2A2,ALG3,RPN1,DDOST,DPM1,STT3A,DAD1,MAN1B1,FUT8,MOGS,B4GALT1,RPN2,B4GALT3,MGAT5,B4GALT2,MAN1A1 |
| 7.588e-04 | -7.18 | NUTT_GBM_VS_AO_GLIOMA_UP | MSigDB lists | NUTT_GBM_VS_AO_GLIOMA_UP | 46 | 16 | 17377 | 2626 |
NUCB1,GALNT2,CLIC4,DDOST,RHOC,PIK3R2,STAT1,TMEM109,LDHA,DCTD,TAGLN2,GPI,TP53BP2,RBBP4,SH3GLB1,TMX1 |
| 7.588e-04 | -7.18 | PID_LKB1_PATHWAY | MSigDB lists | PID_LKB1_PATHWAY | 46 | 16 | 17377 | 2626 |
TSC1,PRKAB1,TSC2,PRKAA1,EZR,CAB39,STK11,YWHAZ,AKT1S1,CREB1,PRKACA,YWHAH,MARK2,SMAD4,MLST8,CDC37 |
| 7.588e-04 | -7.18 | GCM_DENR | MSigDB lists | GCM_DENR | 46 | 16 | 17377 | 2626 |
DDX47,TOR1AIP1,ALKBH5,SUMF2,MBD3,GFM2,ABHD16A,DDX17,ZNF317,MTMR4,TBC1D14,CS,CPSF4,AAAS,CCAR1,S100PBP |
| 7.607e-04 | -7.18 | ATGTACA,MIR-493 | MSigDB lists | ATGTACA,MIR-493 | 304 | 67 | 17377 | 2626 |
ADAM10,TM9SF3,UBE2Q1,CHKB,PAIP1,ANKRD28,ZNF804A,APLP2,ATP2A2,FAM76B,MTPN,ZNF800,CARM1,SRPK2,RYBP,SP3,BAZ2A,MCL1,HERPUD2,ZFAND5,USP21,TRAM2,EIF4ENIF1,AXIN1,ITGB1,RNF38,SEL1L,BAZ1B,NCOA1,SLC22A23,MAPK1,ZBTB11,PRPF38B,EYA1,SDC2,SMC6,MED13L,PPP3CB,XPO7,CSNK1A1,AP3S1,CDC73,ARID1B,FBRS,UBE2Q2,RIMS3,BRD7,BCL2,AHDC1,CITED2,PIKFYVE,LPCAT1,SRSF11,PDPK1,PHF20L1,BTAF1,NUDT4,ARID1A,RHOT1,KPNA4,SERTAD2,ATAD2,USP32,CNOT6,SRSF3,ZMIZ1,SNRNP70 |
| 7.663e-04 | -7.17 | GSE3982_MAST_CELL_VS_BASOPHIL_DN | MSigDB lists | GSE3982_MAST_CELL_VS_BASOPHIL_DN | 176 | 43 | 17377 | 2626 |
WASF2,CYLD,NF1,CTCF,DAZAP2,MAP1LC3B,TTF1,GIT2,HLA-A,PAPOLA,PTPN2,ADD3,RAB4A,BRD7,CEP63,SAP30L,CTDSP2,HTRA2,SMC4,NIPAL3,RB1CC1,SELPLG,RTF1,ARHGDIB,DIDO1,MACF1,SLTM,ARHGAP15,POLR2A,ABHD5,PPP2R5A,ETS2,JAK1,ACOX1,SIAH2,RNF38,CCDC69,VCPIP1,ACTB,DUSP11,FAU,USF2,CCDC59 |
| 7.663e-04 | -7.17 | GSE22601_DOUBLE_NEGATIVE_VS_IMMATURE_CD4_SP_THYMOCYTE_UP | MSigDB lists | GSE22601_DOUBLE_NEGATIVE_VS_IMMATURE_CD4_SP_THYMOCYTE_UP | 176 | 43 | 17377 | 2626 |
TCF12,TOMM20,TXN,SESTD1,SNX15,TKT,SMARCA4,UBE2I,ZER1,RPN1,ZNF473,SIAH1,THAP4,ZNHIT6,XPA,SRI,ZRANB1,SLC35A1,TMEM14C,SYTL3,SMC4,TXNL1,SP3,SNX25,ZNF672,PPP1R9B,TSPYL4,SMU1,ZBED5,PSMA1,RTF1,PRMT2,RHBDF2,XRCC5,SH3BP5,TXNDC16,TWSG1,PRDX3,USP20,TAF12,ZNF45,TMEM14A,SSSCA1 |
| 7.693e-04 | -7.17 | ELM2 | prosite domains | PS51156 | 13 | 7 | 12060 | 1670 |
RCOR1,MIER2,TRERF1,RCOR3,MTA1,MTA2,MIER1 |
| 7.711e-04 | -7.17 | ARL4C (ADP ribosylation factor like GTPase 4C) | protein interactions | 10123 | 21 | 10 | 17029 | 2761 |
TERF2IP,PAF1,UBQLN4,OAF,ARF5,XRCC2,DCUN1D4,APP,RAD51D,TERF2 |
| 7.711e-04 | -7.17 | ASB14 (ankyrin repeat and SOCS box containing 14) | protein interactions | 142686 | 21 | 10 | 17029 | 2761 |
GALK1,ATP2A2,PHB2,TUFM,NOTCH2,CYC1,VDAC1,SLC25A5,ARF4,SLC25A1 |
| 7.711e-04 | -7.17 | KCNIP3 (potassium voltage-gated channel interacting protein 3) | protein interactions | 30818 | 21 | 10 | 17029 | 2761 |
CALM2,PPP3CA,GRK2,IL6ST,MAVS,UBE2I,CLN3,CREB1,PSEN1,CREM |
| 7.711e-04 | -7.17 | CCDC18 (coiled-coil domain containing 18) | protein interactions | 343099 | 21 | 10 | 17029 | 2761 |
FGFR1OP,PCM1,CCDC14,DYNLL1,ODF2,CEP63,GALK2,EYA2,POC5,PRPF19 |
| 7.711e-04 | -7.17 | TMEM33 (transmembrane protein 33) | protein interactions | 55161 | 21 | 10 | 17029 | 2761 |
RPA2,CYLD,MPHOSPH8,RPS14,PTP4A3,ADRB2,MCM2,CLN3,RPA1,ABCC1 |
| 7.711e-04 | -7.17 | PLEKHO2 (pleckstrin homology domain containing O2) | protein interactions | 80301 | 21 | 10 | 17029 | 2761 |
FLAD1,CENPJ,UBR2,FAAP100,CAPZA1,ANAPC7,CAPZA2,APP,PPP2R2D,TACC3 |
| 7.711e-04 | -7.17 | Chmp3 (charged multivesicular body protein 3) | protein interactions | 66700 | 21 | 10 | 17029 | 2761 |
DTL,DNAJC8,NSF,PRDX5,USP39,CHMP4B,KDM3A,STAM,IPO4,FUBP1 |
| 7.715e-04 | -7.17 | SUGT1 (SGT1 homolog, MIS12 kinetochore complex assembly cochaperone) | protein interactions | 10910 | 99 | 29 | 17029 | 2761 |
RPAP3,PLK1,NPHP4,CYLD,POC1A,PSMA1,KLHL18,CSNK2A1,AURKB,PMF1,DDX39A,GLRX3,MIS12,EVC2,PTPRF,C12orf10,CEP104,HSPA4,CLIC4,DSN1,TONSL,PSMD3,FKBP5,WDR76,AHCYL1,S100A6,CFL1,SSSCA1,CDC5L |
| 7.715e-04 | -7.17 | HNRNPH3 (heterogeneous nuclear ribonucleoprotein H3) | protein interactions | 3189 | 99 | 29 | 17029 | 2761 |
COX15,STAU1,EWSR1,CHERP,CUL3,HNRNPF,CUL1,BRCA1,SEC16A,SDHA,RBM4,MATR3,SNRPA,PHF6,SRSF1,CAND1,DDX17,HNRNPA2B1,PLD3,PDCD6,HNRNPR,HNRNPH3,MAPK6,H2AFX,IARS2,DDX5,COPS6,HNRNPDL,ANXA11 |
| 7.716e-04 | -7.17 | IGF2BP3 (insulin like growth factor 2 mRNA binding protein 3) | protein interactions | 10643 | 90 | 27 | 17029 | 2761 |
PPAN,STAU1,RAE1,GSPT2,HNRNPUL2,RPL6,RPL38,DHX9,CUL3,BRCA1,ABCF1,FKBP3,RPL23A,CAND1,HNRNPA2B1,PA2G4,EPRS,MDM2,PDCD6,IARS,QARS,ZNF746,RTCB,DDX5,RBM3,CDK2,HNRNPM |
| 7.721e-04 | -7.17 | regulation of phosphoprotein phosphatase activity | biological process | GO:0043666 | 110 | 30 | 17256 | 2622 |
ANKLE2,PPP1R9B,SHOC2,PPP1R37,PPP1R2,PPP1R12A,PPP1R15B,ENSA,PPP1R16B,MASTL,CALM2,PPP1R3B,FKBP1A,TSC1,UBXN2A,PPP2R5A,UBXN2B,PPP1R8,PPME1,PPP4R1,NSFL1C,PPP1R11,CRY2,CABIN1,ROCK1,PPP6R3,GNAI2,IGBP1,PPP2R2D,PPP6R1 |
| 7.742e-04 | -7.16 | RANGAP1 (Ran GTPase activating protein 1) | protein interactions | 5905 | 122 | 34 | 17029 | 2761 |
PPIB,TP53RK,TMUB1,SUMO2,ACTR3,BABAM1,CSNK2A1,EFL1,UBE2I,LMNA,EEF2K,SUB1,KDM2A,HUWE1,EFTUD2,NUP107,NUP153,CPSF4,RPRD1B,NUP85,SENP1,SEH1L,CDC5L,PPIF,NSUN2,RANGAP1,TOPORS,NDUFA7,BRCA1,SH3GLB1,TPD52L2,MYO18A,RBPJ,ARRB2 |
| 7.753e-04 | -7.16 | ZF_RANBP2_1 | prosite domains | PS01358 | 24 | 10 | 12060 | 1670 |
EWSR1,MDM2,TAB2,NEIL3,NUP153,ZRANB2,FUS,ZRANB1,NPLOC4,RYBP |
| 7.769e-04 | -7.16 | PSMA1 (proteasome subunit alpha 1) | protein interactions | 5682 | 194 | 49 | 17029 | 2761 |
TCF12,MAPRE1,CYLD,ZCCHC8,UBXN1,DCTN2,KCTD17,CUL1,POMP,INO80E,APP,RAD23A,FAM192A,PSMD2,PSMD1,CLIC4,PSMA6,HUWE1,UCHL5,PPCDC,CAPZA1,TXNL1,PLK1,EXOSC6,FOXK1,PSMA8,LDB1,PSMB7,PSMA1,PSMG1,BRCA1,SYVN1,PSMB9,PSMB3,SH3GLB1,RAD54B,PSMC4,DERL1,WDR11,GOLGA2,PSMD8,PSMD3,PPM1G,ZRANB2,MRFAP1L1,PSMC1,COIL,GCSH,DDB1 |
| 7.814e-04 | -7.15 | V$NFY_01 | MSigDB lists | V$NFY_01 | 234 | 54 | 17377 | 2626 |
HIVEP3,WASF2,PRPF38B,ZBTB10,NPHP4,GGNBP2,ZFP91,AGPAT1,KIF23,RACGAP1,NANS,STMN1,SLC20A1,MIS12,BCAT2,ATP2A2,INTS7,UTP18,SSBP3,FUT8,FIZ1,RPN2,PCYT2,MOB1A,SPTSSA,SPSB3,RNF5,TACC3,PLK1,ZNF524,MLEC,KLF10,COQ10B,ABCF2,WBP2,NARF,GORAB,KDM3A,ARL17A,USP21,RHOB,PI4K2A,CAT,SMAD2,ACYP1,HNRNPR,ELMO1,ODF2,ZNF436,DCAF11,ACTB,H3F3A,LRP8,NUMB |
| 7.829e-04 | -7.15 | MOREIRA_RESPONSE_TO_TSA_UP | MSigDB lists | MOREIRA_RESPONSE_TO_TSA_UP | 26 | 11 | 17377 | 2626 |
MIF,TGFB1,BAK1,PA2G4,HMGN1,SELPLG,COX8A,YWHAH,USF2,BYSL,HSPA1B |
| 7.829e-04 | -7.15 | GNF2_SMC1L1 | MSigDB lists | GNF2_SMC1L1 | 26 | 11 | 17377 | 2626 |
POLA2,MCM5,RBMX,BANF1,U2SURP,HNRNPF,RRM2,NUP153,CENPM,SNRPG,DHX15 |
| 7.829e-04 | -7.15 | BIOCARTA_RACCYCD_PATHWAY | MSigDB lists | BIOCARTA_RACCYCD_PATHWAY | 26 | 11 | 17377 | 2626 |
RB1,RHOA,RAF1,TFDP1,RAC1,E2F1,CDKN1B,MAPK1,CDK2,HRAS,MAPK3 |
| 7.829e-04 | -7.15 | GO_PHAGOSOME_ACIDIFICATION | MSigDB lists | GO_PHAGOSOME_ACIDIFICATION | 26 | 11 | 17377 | 2626 |
ATP6V0B,ATP6V1D,RAB7A,ATP6V0A1,ATP6V0A2,ATP6V0C,ATP6V1B2,ATP6V1C1,ATP6V0D1,ATP6V0E1,ATP6V1G1 |
| 7.838e-04 | -7.15 | EZR (ezrin) | protein interactions | 7430 | 160 | 42 | 17029 | 2761 |
HSPH1,PRKAB1,PDCD6IP,H2AFZ,GNPDA1,PTTG1,HEXB,TKT,SDC2,OAT,CDK5,MDM2,CLIC4,PDCD10,PPME1,AKR1B1,TAGLN2,ASB6,SCYL3,GPX4,RHOA,WDR1,MRPL12,EZR,ARHGDIB,BRCA1,ICAM2,MCM2,FADD,ISG15,FAS,HLA-B,TPD52L2,TSC1,HSPA4,TIMM13,AHNAK,PPA2,ACTB,PDXK,ROCK1,HEXA |
| 7.877e-04 | -7.15 | ependymoma_Grade_III-IV | COSMIC cancer mutations | ependymoma_Grade_III-IV | 19 | 9 | 17385 | 2587 |
TSC1,RB1,NRAS,PTEN,KRAS,MEN1,H3F3A,HRAS,CDKN2A |
| 7.877e-04 | -7.15 | soft_tissue-fat-liposarcoma-dedifferentiated | COSMIC cancer mutations | soft_tissue-fat-liposarcoma-dedifferentiated | 19 | 9 | 17385 | 2587 |
RB1,EWSR1,NRAS,NF1,PTEN,NUP107,KRAS,FUS,HRAS |
| 7.877e-04 | -7.15 | ependymoma_Grade_II | COSMIC cancer mutations | ependymoma_Grade_II | 19 | 9 | 17385 | 2587 |
TSC1,RB1,NRAS,PTEN,KRAS,MEN1,H3F3A,HRAS,CDKN2A |
| 7.884e-04 | -7.15 | phosphatase regulator activity | molecular function | GO:0019208 | 90 | 26 | 17224 | 2647 |
ANKLE2,PPP1R9B,SHOC2,PPP1R37,PPP1R2,PPP1R12A,PPP1R15B,ENSA,MTMR12,PPP1R16B,GTF2F1,CALM2,PPP1R3B,UBXN2A,PPP2R5A,UBXN2B,PPP1R8,PPME1,PPP4R1,NSFL1C,PPP1R12C,PPP1R11,ANP32E,CABIN1,IGBP1,PPP2R2D |
| 7.903e-04 | -7.14 | GO_CELLULAR_RESPONSE_TO_REACTIVE_OXYGEN_SPECIES | MSigDB lists | GO_CELLULAR_RESPONSE_TO_REACTIVE_OXYGEN_SPECIES | 101 | 28 | 17377 | 2626 |
PPIF,TNFAIP3,NQO1,NET1,PRKAA1,ETS1,KLF6,PARK7,MTR,PRDX1,RHOB,FAS,PDK2,MDM2,PDCD10,CCNA2,PRDX3,STAT6,PRDX5,DNM2,MPV17,AKR1B1,PKD2,MAP3K5,PPP5C,CDK2,HDAC2,PTPRK |
| 7.903e-04 | -7.14 | GO_TELOMERE_ORGANIZATION | MSigDB lists | GO_TELOMERE_ORGANIZATION | 101 | 28 | 17377 | 2626 |
POLA2,ERCC1,RFC3,PRIM2,PRKDC,SMC6,DCLRE1C,RFC2,GAR1,RPA1,XRCC5,PRIM1,DOT1L,TERF2IP,RPA2,RAD51C,PCNA,UPF1,POLE,SP100,NSMCE2,XRCC3,PTGES3,H3F3A,TERF1,POT1,RAD51D,TERF2 |
| 7.913e-04 | -7.14 | GO_TRANSLATION_FACTOR_ACTIVITY_RNA_BINDING | MSigDB lists | GO_TRANSLATION_FACTOR_ACTIVITY_RNA_BINDING | 82 | 24 | 17377 | 2626 |
EIF5A,EIF3L,DHX29,EIF3D,GSPT2,TUFM,EIF2A,EIF1B,EIF4G2,EIF4H,EIF3G,ABCF1,GFM2,EIF3H,EIF3A,MCTS1,EEF2K,EIF3K,EIF2S2,EIF2D,EIF5,GTF2H2,CPEB2,EEF1D |
| 7.967e-04 | -7.14 | SIRT1 (sirtuin 1) | protein interactions | 23411 | 244 | 59 | 17029 | 2761 |
SART1,NCOR2,RPS2,EWSR1,MCM10,TSC2,MPHOSPH8,SUZ12,CSNK2A1,CHCHD2,SIRT2,LANCL1,CCNB1,SPDL1,SUPT7L,UBE2I,FOXO3,PAPOLA,RB1,RAP1A,MDM2,MTA1,ZNHIT6,FBXO7,YBX1,AHCY,CREB1,STAT3,DNMT1,DVL2,KCNAB2,BRD4,KAT2A,VHL,MTFR2,RPL6,USP22,PICALM,TRIM28,DOT1L,TAF2,HSPA4,JAK1,RBM25,CHD3,CLK3,TULP3,ARNTL,LRPPRC,PML,E2F1,STK11,KPNA2,CHEK2,DVL1,ZMIZ1,ARRB2,LTA4H,HDAC2 |
| 7.969e-04 | -7.13 | GSE37533_PPARG1_FOXP3_VS_PPARG2_FOXP3_TRANSDUCED_CD4_TCELL_UP | MSigDB lists | GSE37533_PPARG1_FOXP3_VS_PPARG2_FOXP3_TRANSDUCED_CD4_TCELL_UP | 166 | 41 | 17377 | 2626 |
CTU2,CMAS,PKP4,ST13,KRBA1,CXXC1,RHOC,RPS6KA1,CDC42SE2,XPNPEP3,RNF103,SAC3D1,NSRP1,DAD1,RPF2,FAM76B,MAML1,LYPLA2,AMPD2,SLC39A9,KAT2A,FAM118B,CDC123,RDH10,WDR18,CRNKL1,ELP4,USP10,DIDO1,DCLRE1C,MEN1,ZDHHC3,SDHB,TMEM41A,GOLGA4,AXIN1,ZC3H7B,MLYCD,SAMD8,ZMAT3,GCSH |
| 7.991e-04 | -7.13 | GO_REGULATION_OF_DNA_METABOLIC_PROCESS | MSigDB lists | GO_REGULATION_OF_DNA_METABOLIC_PROCESS | 321 | 70 | 17377 | 2626 |
MBD1,USP7,DNMT3A,MPHOSPH8,THOC1,FOXM1,RAC1,TERF2IP,PCNA,SHC1,CDC42,NVL,DNMT1,OGG1,RNF169,CCT2,ERCC1,RFC3,RAD51AP1,UBE2V1,CDC6,AURKB,BRCA1,KDM1B,RFC2,MBD3,TRIM28,STOML2,MAP3K4,PPP2CA,STAT6,H2AFX,KPNA2,CHEK2,ARRB2,MAPK1,POT1,POLQ,DNAJC2,TRIP12,MECP2,CHTF18,EYA1,BABAM1,CDT1,BLM,TTF1,WRNIP1,RPA2,SMC3,AXIN2,MSH2,MSH6,TERF2,TGFB1,NEK7,HELB,GTPBP4,MEN1,CCT8,MAPK3,XRCC5,KPNA1,CEBPG,PML,ZNF830,CDK2,HRAS,TERF1,CDKN2A |
| 8.016e-04 | -7.13 | SSX2IP (SSX family member 2 interacting protein) | protein interactions | 117178 | 224 | 55 | 17029 | 2761 |
FGFR1OP,MAPRE1,LUZP1,DYNLL1,PRKAA1,XIAP,C19orf25,HAUS4,WDR5,PHC2,FANCL,CEP104,CDC42,CENPJ,AP1M1,GPATCH1,CEP63,NAP1L4,TP53BP2,POC5,DVL2,CCAR1,NOL12,NTPCR,CCDC138,CAMSAP1,PSMA1,SREK1,ADSL,BRCA1,CDC23,ECH1,HAUS8,AFDN,CHCHD3,TRIM26,PCM1,EIF4ENIF1,CCDC14,MFAP1,ODF2,CDCA7L,CEP55,PTAR1,VCPIP1,AEN,XRCC3,YWHAZ,KLHL42,DVL1,USP11,SASS6,PDLIM5,BYSL,ZBTB24 |
| 8.028e-04 | -7.13 | WANG_TARGETS_OF_MLL_CBP_FUSION_DN | MSigDB lists | WANG_TARGETS_OF_MLL_CBP_FUSION_DN | 42 | 15 | 17377 | 2626 |
CAT,CCDC86,TMED10,HARS,CPOX,TMEM109,LACTB,GTPBP4,VDAC1,PITRM1,GLRX3,NMD3,FTSJ3,STRAP,NIPSNAP1 |
| 8.028e-04 | -7.13 | MODULE_86 | MSigDB lists | MODULE_86 | 42 | 15 | 17377 | 2626 |
RAB8A,RAP1A,CDC42,RALB,ARF5,RAC1,KRAS,RIT1,ARF1,RAB1A,EIF5,RAB11A,HRAS,RHEB,ARF4 |
| 8.028e-04 | -7.13 | MODULE_332 | MSigDB lists | MODULE_332 | 42 | 15 | 17377 | 2626 |
RB1,HSPBP1,EWSR1,TXNDC16,DCAF8,TPP2,SRSF6,ZBED5,ILF3,MKI67,RRM1,ARGLU1,GTF3A,EML4,PCBP2 |
| 8.028e-04 | -7.13 | GO_POSITIVE_REGULATION_OF_MRNA_METABOLIC_PROCESS | MSigDB lists | GO_POSITIVE_REGULATION_OF_MRNA_METABOLIC_PROCESS | 42 | 15 | 17377 | 2626 |
PAF1,UPF1,POLR2G,HNRNPR,BTG2,RBMX,TRA2B,THRAP3,SNRNP70,CCNB1,CDC73,PABPC1,TOB1,ZC3HAV1,PRPF19 |
| 8.032e-04 | -7.13 | TECR (trans-2,3-enoyl-CoA reductase) | protein interactions | 9524 | 64 | 21 | 17029 | 2761 |
COX15,NDUFS1,SCAMP3,VDAC2,MOGS,CUL3,GORASP2,RAB1A,VDAC1,RHOT2,SSR1,CAND1,RPN1,ATP1A1,SEC61A1,DDOST,MAGT1,MBOAT1,XRCC3,ACADM,CLN3 |
| 8.032e-04 | -7.13 | HSPA4L (heat shock protein family A (Hsp70) member 4 like) | protein interactions | 22824 | 64 | 21 | 17029 | 2761 |
DNAJC2,NUP188,TKT,DHX9,EZR,DNAJC9,BRCA1,DNAJA1,DNAJB1,PAIP1,DNAJC10,DNAJC8,HINT1,DUT,STAT1,PPP1R11,TTC4,TAGLN2,USF2,LUC7L2,TERF2 |
| 8.032e-04 | -7.13 | BID (BH3 interacting domain death agonist) | protein interactions | 637 | 64 | 21 | 17029 | 2761 |
BAK1,RHOA,CRNKL1,EZR,CSNK2A1,MCL1,BCL2L1,UBQLN2,CSNK1A1,FADD,RPA1,ARL6IP6,FAS,CAPN2,RPA2,ZHX1,BCL2,AHCYL1,PACS2,CAPN1,CDC5L |
| 8.045e-04 | -7.13 | GSE411_100MIN_VS_400MIN_IL6_STIM_SOCS3_KO_MACROPHAGE_UP | MSigDB lists | GSE411_100MIN_VS_400MIN_IL6_STIM_SOCS3_KO_MACROPHAGE_UP | 192 | 46 | 17377 | 2626 |
IER2,MAGEH1,DNMT3A,CHTF18,SRGN,UROD,LAGE3,NCKAP1,ARF1,IKBIP,APP,RNF103,SRXN1,ZNF428,MLX,RRBP1,RPN2,ARL5A,CCAR1,KCNAB2,EBAG9,RHOA,MAPRE2,GUK1,CDC123,NEK7,PBK,RAD51AP1,OXR1,TLK1,TMEM147,SH3GLB1,AKAP1,CHCHD3,PPP2CA,KIF18A,NEIL3,CTBS,UHRF2,C4orf46,PPP1R11,DMWD,REEP4,BRWD3,RTN3,PPP2R2D |
| 8.045e-04 | -7.13 | GSE1432_CTRL_VS_IFNG_24H_MICROGLIA_UP | MSigDB lists | GSE1432_CTRL_VS_IFNG_24H_MICROGLIA_UP | 192 | 46 | 17377 | 2626 |
TMEM106C,RMND5A,FEZ2,SMAP1,GNPDA1,GGA1,MUM1,UROD,CUTA,TRAK1,CERK,RPL15,AP1B1,OAT,ITGB5,FOXO3,CCDC28A,PABPC4,NFATC3,RIMS3,FUT8,FBXW2,TTC3,ZNF710,LPCAT1,NUP85,ALDH9A1,ABCC5,CDKN2AIP,RB1CC1,PPT1,ZMYND11,DNAJC9,UBE4B,CADM1,MCM2,KDM3A,RPA1,MOSPD3,MKNK1,SLC38A7,CHD3,PSAP,ZMIZ1,LTA4H,RTN3 |
| 8.045e-04 | -7.13 | GSE10240_CTRL_VS_IL17_AND_IL22_STIM_PRIMARY_BRONCHIAL_EPITHELIAL_CELLS_DN | MSigDB lists | GSE10240_CTRL_VS_IL17_AND_IL22_STIM_PRIMARY_BRONCHIAL_EPITHELIAL_CELLS_DN | 192 | 46 | 17377 | 2626 |
ZNF296,H2AFZ,MCM10,IVNS1ABP,C1orf112,CDCA3,CDCA8,TIA1,KIF23,ABCB10,CNTROB,ARID1B,SPAG5,EEF2K,ABL2,ZNF428,ATP2A2,LPIN2,TIMELESS,H2AFY,KIF22,UPF2,CENPM,AMPD2,CLCN3,RHOBTB3,CCDC138,EHMT1,CIRBP,RRM2,CKAP2L,CDCA2,LUC7L,TRIM28,RHOB,RXRB,ZMYM3,GPR137,CACNB1,TTC13,SCAP,CCDC14,CDCA5,EXOC4,TFDP2,ESPL1 |
| 8.045e-04 | -7.13 | GSE22886_DC_VS_MONOCYTE_UP | MSigDB lists | GSE22886_DC_VS_MONOCYTE_UP | 192 | 46 | 17377 | 2626 |
SEPHS2,KCTD7,NDUFV2,AP3M2,SDC2,STARD7,ZFYVE21,NIT2,NENF,POLR3K,LMNA,CHKA,EBP,ZNF804A,HOMER1,ZCCHC2,EFCAB11,SEPT11,KIFAP3,DNMT1,MTX2,SPTAN1,GINS1,NAGPA,HMGN1,NET1,DENND1B,SLC17A5,PI4K2A,EPRS,MKNK1,PON2,PCM1,HSPA4,SERF2,TWSG1,PPA2,MLYCD,SLC16A1,MDH1,TRIM32,CHEK2,EHD4,CD81,PFKP,ANXA11 |
| 8.086e-04 | -7.12 | cellular response to topologically incorrect protein | biological process | GO:0035967 | 150 | 38 | 17256 | 2622 |
HSPH1,ATXN3,ADD1,SEC61G,CXXC1,SDF2L1,RHBDD1,DNAJB9,LMNA,SSR1,RNF121,SHC1,MYDGF,PDIA6,CTDSP2,ATP6V0D1,RNF5,PREB,DCTN1,BAK1,SEC61B,ERO1A,CUL3,SYVN1,EDEM2,SERP1,HSPA1B,OPTN,ANKZF1,SEC31A,YIF1A,DERL1,HSPA4,SEC61A1,TATDN2,KLHL15,ATF6,ASNA1 |
| 8.107e-04 | -7.12 | GO_NEGATIVE_REGULATION_OF_MOLECULAR_FUNCTION | MSigDB lists | GO_NEGATIVE_REGULATION_OF_MOLECULAR_FUNCTION | 1029 | 192 | 17377 | 2626 |
FGFR1OP,TSC2,UBN1,NF1,XIAP,ENSA,CSNK2A1,CCNB1,BIRC2,PARK7,PRNP,CALM2,CDKN2C,PSMD1,EIF4A3,GLIS2,SIVA1,SRI,CRY2,CARM1,PLK1,NCK1,AKT2,GMFB,LRP5,AURKB,PRPSAP1,BRMS1,HHEX,RPS27A,PSMD8,LIMK1,PRDX5,SOCS4,CAB39,ROCK1,DVL1,CLN3,ARRB2,PSMC1,OAZ1,POT1,HDAC2,PDCD4,MAPRE1,ZCCHC9,GMFG,PPP1R12A,PPP1R2,PHB2,UBXN1,CIB1,EIF2AK4,RGS2,PSMD9,PSEN1,RTKN,FKBP1A,TFAP4,RB1,FBXO7,ARL6IP1,PIK3IP1,MVP,GNAI2,TMED2,TERF2,SOCS5,GBA,GTPBP4,PSMA1,ADRB2,PSMB3,CAND1,PSMC4,MASTL,PTPRF,CAT,MBIP,HSPBP1,CDC27,GOLGA2,DUSP3,CSK,SIAH2,PIAS2,NLRC5,CEBPG,ZFP90,NUP62,CABIN1,GPI,RUVBL2,CDK2,ZC3HAV1,CDKN2A,EGLN1,USP7,PPP1R37,CYLD,NQO1,CAST,RPS6KA1,RAF1,PTTG1,ANK3,WDTC1,DUSP22,LYN,APP,APLP2,MDM2,PSMA6,TNFAIP8,SP100,RALB,UCHL5,PPME1,PIN1,SOCS6,CDKN1B,ANAPC7,RLIM,CPNE1,PPIF,TIMP2,BIRC3,PSMB7,CUL3,PKMYT1,DNAJA1,CDC23,PSMB9,SOCS7,PPP2CA,CDC16,PPP2R5A,HNRNPR,PSMD3,CORO1C,STK38,GADD45B,ANP32E,BCL2L12,DAP,HABP4,AKT1S1,MAD2L2,FZD6,FBXO5,WWP2,PTPN2,PSMD2,PTEN,PPP1R8,ANXA5,H2AFY,GTSE1,PDPK1,PPP1R9B,PPP3CA,TNFAIP3,BTAF1,PRKAR1B,RFFL,ANAPC2,WDR81,KCNQ1,MEN1,PRMT2,PICALM,MAPK3,SH3BP5,KEAP1,PRDX3,BIRC5,GPS2,OAZ2,E2F1,PML,PPP1R11,PKD2,NR2F2,UBE2C,PARP10,IGBP1,CPEB2,HIPK3,TERF1,HRAS,IFI16,ANAPC4 |
| 8.138e-04 | -7.11 | ACACA (acetyl-CoA carboxylase alpha) | protein interactions | 31 | 77 | 24 | 17029 | 2761 |
PRKAB1,DCAF6,SUZ12,RPS6KA1,PRKAA1,PSMB7,ATXN1,CSNK2A1,NDUFA4,BRCA1,CSNK1A1,EEF2K,KIF5B,PSMD2,MDM2,GRK2,SHC1,IARS,PTEN,PIK3R2,ZNF746,SOCS6,FUS,PHKG2 |
| 8.138e-04 | -7.11 | Htt (huntingtin) | protein interactions | 15194 | 77 | 24 | 17029 | 2761 |
COX5B,NDUFS1,PHB2,DNAJB2,RAC1,VDAC2,SLC25A12,CHCHD2,SEPT7,VDAC1,BCAP31,CCT8,EPB41,PRNP,CD59,DPYSL2,COX5A,NDUFB9,UQCRH,MDH1,CYC1,NDUFS5,EEF1D,DDB1 |
| 8.158e-04 | -7.11 | heat shock protein binding | molecular function | GO:0031072 | 114 | 31 | 17224 | 2647 |
DNAJC2,HSPH1,TELO2,TSC2,ST13,DNAJB2,DNAJC9,CSNK2A1,DNAJA1,DNAJB1,METTL22,DNAJB9,HSPA1B,CDK5,PDXP,TSC1,DNAJC10,HSPA4,DNAJC8,LIMK1,AHSA1,CAMKMT,ARNTL,NUP62,FKBP5,PTGES3,TTC4,PPP5C,HDAC2,FAF1,CDC37 |
| 8.207e-04 | -7.11 | strand displacement | biological process | GO:0000732 | 26 | 11 | 17256 | 2622 |
RAD51C,PALB2,RAD51AP1,XRCC2,TOP3A,RMI2,XRCC3,BRCA1,BLM,RMI1,RAD51D |
| 8.213e-04 | -7.10 | negative regulation of protein ubiquitination | biological process | GO:0031397 | 68 | 21 | 17256 | 2622 |
TRIP12,TNFAIP3,UBXN1,GTPBP4,DNAJA1,SOX4,PSEN1,PARK7,MAD2L2,ISG15,HSPA1B,FBXO5,RPL11,CDK5,PLAA,GPS2,LIMK1,OGT,PARP10,ARRB2,CHP1 |
| 8.229e-04 | -7.10 | GSE16385_IFNG_TNF_VS_ROSIGLITAZONE_STIM_MACROPHAGE_UP | MSigDB lists | GSE16385_IFNG_TNF_VS_ROSIGLITAZONE_STIM_MACROPHAGE_UP | 156 | 39 | 17377 | 2626 |
RAB11B,DBF4,NKD2,BRAP,IKBIP,PDCD7,CHD1,PRPF18,ANKRD39,RPL11,PAPOLA,MED10,ATIC,DDX31,FAM76B,TFG,RBM15,NSUN4,SPSB3,SRSF10,METTL1,PLK1,RBM42,HMGN4,PSMA1,COG1,FRAT2,OTUD3,ANLN,RAB2B,TFEB,PSMC4,ORMDL2,CSNK1G1,PPA2,IMPDH1,MRFAP1L1,DVL1,C7orf26 |
| 8.258e-04 | -7.10 | GSE8835_CD4_VS_CD8_TCELL_UP | MSigDB lists | GSE8835_CD4_VS_CD8_TCELL_UP | 187 | 45 | 17377 | 2626 |
PPCS,UBR2,CDT1,TMX4,RAB23,CUL1,ZNRF3,THRAP3,B4GALT4,RGS2,ASXL2,REEP5,SDHA,NUP205,CLUAP1,PRKD3,NUP210,HUWE1,CAPZA1,FEM1B,MAST2,AHCYL1,SLC12A2,PABPC1,DVL2,TIMP2,SNRNP200,PRKDC,ZMYND11,BMS1,LRP5,UBE4B,UTP3,MTR,SLCO4A1,PALB2,POLE,ELMO1,SEL1L,LMBR1,SH3GLB2,LTA4H,PDLIM5,TMEM131,CCDC137 |
| 8.258e-04 | -7.10 | GSE17721_CTRL_VS_PAM3CSK4_12H_BMDC_UP | MSigDB lists | GSE17721_CTRL_VS_PAM3CSK4_12H_BMDC_UP | 187 | 45 | 17377 | 2626 |
MRPS15,ADAM10,IVNS1ABP,GADD45G,COX4I1,NANS,COMMD5,BECN1,RCOR3,EXT2,BCAP31,XPR1,FAM192A,GSTK1,CCNA2,ATG3,BDH1,SOCS6,HADHB,TECR,PLCL2,MSH6,MED22,FDFT1,VOPP1,PPP3CA,CYTH1,PTPN18,GALC,IDH3A,NQO2,OXR1,ZNF574,KCTD20,EMP3,MEF2D,VDAC1,ANLN,SLC50A1,HAUS8,APPL2,MDH1,C11orf1,PTDSS1,HIGD2A |
| 8.258e-04 | -7.10 | GSE29164_CD8_TCELL_VS_CD8_TCELL_AND_IL12_TREATED_MELANOMA_DAY3_UP | MSigDB lists | GSE29164_CD8_TCELL_VS_CD8_TCELL_AND_IL12_TREATED_MELANOMA_DAY3_UP | 187 | 45 | 17377 | 2626 |
HIVEP3,MRPS2,URB2,PPP1R15B,RAF1,TRIO,TRAK1,TKT,CERK,MEF2A,TMED3,HMG20A,ARL6IP6,GOLM1,PRKD3,CTNNBL1,KLHL20,SNX18,RABGAP1L,GMEB1,INTS12,BRD7,NDUFB9,CORO1A,RNF169,VPS13B,TTPAL,ZNF672,PHF10,WIPF1,PNPLA8,FXR1,DDX39A,API5,STOML2,MKNK1,ATP6V1D,KLHL15,IARS2,ZDHHC7,PIEZO1,SCARB1,WDR62,TMEM159,CWC25 |
| 8.258e-04 | -7.10 | GSE25123_CTRL_VS_ROSIGLITAZONE_STIM_MACROPHAGE_UP | MSigDB lists | GSE25123_CTRL_VS_ROSIGLITAZONE_STIM_MACROPHAGE_UP | 187 | 45 | 17377 | 2626 |
COX15,PPP1R37,MAX,ANKRD13D,GPR132,HLA-E,TRIM11,DLGAP4,KLHL18,LETMD1,CHIC2,PABPC4,CNOT3,BCAT2,SHC1,KDM2A,ARF5,PELO,AP2B1,CITED2,CNNM3,GPX4,EIF5A,CYTH1,PPP1R18,TMEM115,SEPT9,CREG1,MTA2,DCAF8,USP22,ARPC1A,FANCE,EPB41,C1orf122,UAP1,CSK,ZNF689,STAT6,MAPK6,ZFP90,MBD6,AKNA,SNRNP70,SLC25A39 |
| 8.258e-04 | -7.10 | GSE46606_IRF4MID_VS_WT_CD40L_IL2_IL5_DAY3_STIMULATED_BCELL_UP | MSigDB lists | GSE46606_IRF4MID_VS_WT_CD40L_IL2_IL5_DAY3_STIMULATED_BCELL_UP | 187 | 45 | 17377 | 2626 |
HIVEP3,IER2,RRP15,PPP1R15B,ARID5A,STARD7,PLAGL2,MED13L,CREBL2,SNN,BRIX1,CSNK1A1,PTPN2,HNRNPA2B1,CLIC4,PDCD10,INTS12,AFF1,C8orf59,TMBIM1,SEH1L,RYBP,YTHDC1,ETV3,MAPKAPK3,NCK1,HARS,OAF,PGS1,PFKFB3,RFFL,EZR,ZFAND5,KLF6,APPL1,DHX15,RAD54B,OPTN,WDR59,NFIL3,MAPK6,CBLN2,BTF3,MAP3K5,LRCH1 |
| 8.258e-04 | -7.10 | GSE5099_UNSTIM_VS_MCSF_TREATED_MONOCYTE_DAY7_DN | MSigDB lists | GSE5099_UNSTIM_VS_MCSF_TREATED_MONOCYTE_DAY7_DN | 187 | 45 | 17377 | 2626 |
BCL2L12,TRIM41,IER2,PKP4,ADO,AP3M2,MAN2B1,ARF1,ETS1,CFLAR,FKBP1A,TNS3,INTS1,GMEB1,CS,ORAI1,CPSF4,ZNF710,GM2A,AMPD2,HELB,GBA,KCTD20,ATP6V0A1,PLEC,WDR81,MEN1,PRPSAP1,KLF6,USP36,POLR2A,RBM38,RHBDF2,ZMYM3,ALKBH6,SOCS7,NUCB1,HGS,PEX5,CHD3,PML,SMPD4,HEXA,NAA60,SMAD4 |
| 8.258e-04 | -7.10 | GSE19888_CTRL_VS_A3R_ACTIVATION_MAST_CELL_UP | MSigDB lists | GSE19888_CTRL_VS_A3R_ACTIVATION_MAST_CELL_UP | 187 | 45 | 17377 | 2626 |
BCL2L12,RPS2,COPA,HMGXB3,MDH2,TAP1,STRN4,ARGLU1,THRAP3,CCNL2,ARF1,SRRT,COPG2,HMG20A,NRF1,RPAP1,CYC1,CENPM,KDM3B,PLK1,TRIM8,DPM1,BAZ2A,RAD51AP1,UTP15,ILF3,GORASP2,MEF2D,LUC7L,TRIM28,RAD54B,DDX17,ADSS,MTMR3,MAP3K4,CAT,SCARB2,KIF18B,RBM25,DTX4,NLRC5,FAM83D,ATP6V0C,MYL12B,TUBB |
| 8.258e-04 | -7.10 | KAECH_NAIVE_VS_DAY8_EFF_CD8_TCELL_UP | MSigDB lists | KAECH_NAIVE_VS_DAY8_EFF_CD8_TCELL_UP | 187 | 45 | 17377 | 2626 |
SLC12A7,CHERP,DNAJB2,MCCC1,TIA1,NIT2,GGA2,CRLF3,C19orf48,BZW2,APP,PIP4K2A,CFLAR,CTSS,RABGAP1L,IL6ST,SLC44A1,DCP1A,TTC3,METTL9,FRMD8,ABCC5,POU2AF1,ATP13A1,ZMYND11,CAMSAP1,RPL6,MAP4K3,RAB3IP,VKORC1,HAGH,MAT2A,RBM38,ANKRD10,FBXO21,ETS2,ACYP1,RNF38,DVL1,WIPI2,SMAD1,RPS6KC1,EYA2,IPO4,PTOV1 |
| 8.258e-04 | -7.10 | GSE15330_HSC_VS_GRANULOCYTE_MONOCYTE_PROGENITOR_IKAROS_KO_DN | MSigDB lists | GSE15330_HSC_VS_GRANULOCYTE_MONOCYTE_PROGENITOR_IKAROS_KO_DN | 187 | 45 | 17377 | 2626 |
SLC30A9,UNK,PTMS,IMMT,TP53RK,SUCLG1,MRPS2,MANBA,SRSF6,HMGN3,CHKB,ADPGK,RGS2,LYRM2,VPS25,SRRT,HMG20A,MCTS1,CCNK,HOMER1,DPYSL2,PPCDC,GEMIN6,RPAP1,CYB5R1,ECD,PACS2,MLST8,MND1,KAT2A,NOA1,NUDT4,ADSL,SF3A2,TSR2,GLOD4,PPP2R5A,CSK,COX7A2L,PGRMC1,IARS2,SLAIN1,PURA,FAF1,SSRP1 |
| 8.258e-04 | -7.10 | GSE360_T_GONDII_VS_B_MALAYI_LOW_DOSE_MAC_UP | MSigDB lists | GSE360_T_GONDII_VS_B_MALAYI_LOW_DOSE_MAC_UP | 187 | 45 | 17377 | 2626 |
SRM,ATXN3,MPHOSPH8,NDUFB6,SRGN,GADD45G,SDC2,C5orf30,REPS1,MAN1A1,CALM2,CDKN2C,CCP110,ATP2A2,ATIC,BANF1,CYC1,AHCYL1,PCBP2,SLC25A1,SP3,RHOBTB3,PGGT1B,TSPAN31,SLBP,BMS1,AURKB,PCGF1,MCM2,MEN1,ODC1,MBD3,SNRPA,SUGP1,UBTF,ALG3,PCM1,BRWD1,GADD45B,U2SURP,NCOA1,PDXK,SMAD1,PURA,ESPL1 |
| 8.258e-04 | -7.10 | GSE15330_LYMPHOID_MULTIPOTENT_VS_MEGAKARYOCYTE_ERYTHROID_PROGENITOR_UP | MSigDB lists | GSE15330_LYMPHOID_MULTIPOTENT_VS_MEGAKARYOCYTE_ERYTHROID_PROGENITOR_UP | 187 | 45 | 17377 | 2626 |
TCF12,UNK,COX15,PLXNC1,MUT,TMBIM4,TM9SF4,MANBA,C16orf87,PAWR,EZH1,IFT27,PARN,SDHA,CD320,TFAP4,FBXL6,SMC3,PTEN,THAP4,BDH1,PPCDC,RPN2,APOOL,MLST8,SRPK2,ACSL5,RPP25,TIMM8B,MAPRE2,IDH3A,ZNF202,MRPL16,CADM1,ASB13,MPG,FOXRED1,GOLGA4,STAT6,SOCS4,NAA20,TRAF5,CBX4,PARD3,AAAS |
| 8.282e-04 | -7.10 | APC/C:Cdc20 mediated degradation of mitotic proteins | REACTOME pathways | R-HSA-176409 | 76 | 24 | 10287 | 1696 |
PSMA8,PTTG1,PSMB7,PSMA1,ANAPC2,CDC23,CCNB1,PSMD9,PSMB9,PSMB3,PSMC4,PSMD2,PSMA6,CCNA2,CDC16,PSMD1,CDC27,RPS27A,PSMD8,PSMD3,ANAPC7,UBE2C,PSMC1,ANAPC4 |
| 8.336e-04 | -7.09 | CAFFAREL_RESPONSE_TO_THC_DN | MSigDB lists | CAFFAREL_RESPONSE_TO_THC_DN | 30 | 12 | 17377 | 2626 |
CALM2,PPIF,HSPH1,CCNA2,TMEM109,RRM2,SRSF3,DNAJA1,RBM4,TUBB,PABPC4,EBP |
| 8.336e-04 | -7.09 | REACTOME_DNA_STRAND_ELONGATION | MSigDB lists | REACTOME_DNA_STRAND_ELONGATION | 30 | 12 | 17377 | 2626 |
GINS1,POLA2,RPA2,PCNA,RFC3,PRIM2,MCM5,MCM2,RFC2,GINS4,RPA1,PRIM1 |
| 8.336e-04 | -7.09 | GCM_MAX | MSigDB lists | GCM_MAX | 30 | 12 | 17377 | 2626 |
CSDE1,MAX,SMAD2,NOL11,RBM25,HNRNPR,BANF1,MEMO1,TARDBP,FAM76B,MTPN,CCAR1 |
| 8.336e-04 | -7.09 | GNF2_GLTSCR2 | MSigDB lists | GNF2_GLTSCR2 | 30 | 12 | 17377 | 2626 |
RPS15,RPL35,RPLP2,RPS14,RPLP1,RPS10,RPL38,RPL19,FAU,RPS9,EEF1D,RPL23A |
| 8.336e-04 | -7.09 | GSE45365_WT_VS_IFNAR_KO_BCELL_DN | MSigDB lists | GSE45365_WT_VS_IFNAR_KO_BCELL_DN | 151 | 38 | 17377 | 2626 |
FGFR1OP,GLT8D1,TRERF1,DEPDC1,FOXM1,PTTG1,SLC2A1,CENPF,RMI2,NUF2,STMN1,SPAG5,OIP5,RIMS3,KIF14,NIPSNAP1,RAD51AP1,MKI67,WDHD1,CKAP2L,NUSAP1,CDCA2,AURKB,ANLN,KIF11,ASF1B,KIF18B,BIRC5,NEIL3,CORO1C,MAFK,CEP55,CDCA5,LPCAT4,FAM83D,CCNB2,ESPL1,POLQ |
| 8.336e-04 | -7.09 | GSE3920_IFNB_VS_IFNG_TREATED_ENDOTHELIAL_CELL_UP | MSigDB lists | GSE3920_IFNB_VS_IFNG_TREATED_ENDOTHELIAL_CELL_UP | 151 | 38 | 17377 | 2626 |
PKP4,CLSPN,SESTD1,CERK,KIF23,STMN1,CRLF3,CUTC,DTL,DST,RAB4A,TXLNA,MYBL1,RNLS,POLR2G,EMB,RPL38,LRP5,RAB3IP,TANC1,SHCBP1,PI4K2A,RPL37,SH3BP5,KIF18B,PDLIM1,TXNDC16,RPL32,HIPK2,NSMCE2,CDCA5,ARNTL,H2AFX,RNF38,CENPT,SMAD1,RPS26,FAM72A |
| 8.346e-04 | -7.09 | GO_CYTOSKELETON_DEPENDENT_CYTOKINESIS | MSigDB lists | GO_CYTOSKELETON_DEPENDENT_CYTOKINESIS | 38 | 14 | 17377 | 2626 |
PLK1,RHOA,SNX18,ACTR3,ANK3,CEP55,KIF23,RACGAP1,NUSAP1,CHMP4B,AURKB,CNTROB,ANLN,STMN1 |
| 8.347e-04 | -7.09 | MYO19 (myosin XIX) | protein interactions | 80179 | 175 | 45 | 17029 | 2761 |
IMMT,PPP1R12A,LUZP1,ACTR3,RAC1,DCTN2,FLOT1,MYH9,CDC42SE2,SEC16A,MAPK14,GNB2,MYL6B,GART,ADD3,TTC9C,CAPZA1,GTSE1,AP2B1,CLTB,PHKG2,MICAL3,CFL1,MYO5A,DCTN1,SPTAN1,PPP1R9B,PPP1R18,WDR1,VDAC2,CAPZA2,PLEC,ERBIN,VDAC1,ANLN,RHOT2,PICALM,DAPK3,CHCHD3,INF2,NAP1L1,AHNAK,CORO1C,MYO18A,CHMP4B |
| 8.352e-04 | -7.09 | EPB41L3 (erythrocyte membrane protein band 4.1 like 3) | protein interactions | 23136 | 104 | 30 | 17029 | 2761 |
GID8,RPS15,SCOC,DYNLL1,SNRPB,PIP4K2C,RNPS1,C1orf35,CSNK2A1,CADM1,AP3S1,PSEN1,PIP4K2A,DHX15,CLNS1A,TAF2,DERL1,LYAR,MBIP,EIF4A3,CWC27,HUWE1,ZRANB2,YWHAZ,ARRB2,YWHAH,SMURF1,DDB1,PRPF4B,CDC5L |
| 8.352e-04 | -7.09 | CTR9 (CTR9 homolog, Paf1/RNA polymerase II complex component) | protein interactions | 9646 | 104 | 30 | 17029 | 2761 |
DNMT3A,POLR2G,ELL2,ZFP91,ELOA,PMS2,POLR2D,CSNK2A1,RTF1,SOX4,GAR1,CDK11A,CHD1,CDC73,POLR2A,IWS1,SUPT16H,SUGP1,PAF1,VEZF1,MBIP,ALDH3B1,GRK2,KLF16,DGCR8,PTPN11,TCEA1,STAT3,SSRP1,TMEM131 |
| 8.352e-04 | -7.09 | LATS1 (large tumor suppressor kinase 1) | protein interactions | 9113 | 104 | 30 | 17029 | 2761 |
MOB4,PLK1,NPHP4,PKP4,PPP1R12A,RAF1,RAC1,XIAP,AURKB,CNTROB,UBE2I,SEC16A,TAZ,APP,MOAP1,MDM2,GOLGA2,TNFAIP8,CCP110,PTEN,LIMK1,RAB35,PPP1R11,MAST2,PPP6R3,MOB1A,CDK2,SMURF1,PARD3,HTRA2 |
| 8.352e-04 | -7.09 | GO_REGULATION_OF_INTRACELLULAR_STEROID_HORMONE_RECEPTOR_SIGNALING_PATHWAY | MSigDB lists | GO_REGULATION_OF_INTRACELLULAR_STEROID_HORMONE_RECEPTOR_SIGNALING_PATHWAY | 55 | 18 | 17377 | 2626 |
PHB2,SMARCA4,BRCA1,PRMT2,PARK7,DDRGK1,DDX17,ARNTL,UBA5,BUD31,PIAS2,DDX5,CRY2,PPP5C,ARRB2,RNF14,NCOA2,CARM1 |
| 8.354e-04 | -7.09 | soft_tissue-sarcoma | COSMIC cancer mutations | soft_tissue-sarcoma | 47 | 16 | 17385 | 2587 |
EWSR1,NRAS,SF3B1,RAC1,KRAS,CDKN2C,GNAS,RB1,FGFR3,AXIN1,PTPN11,FUS,H3F3A,STAT3,HRAS,CDKN2A |
| 8.360e-04 | -7.09 | MORF_CCNF | MSigDB lists | MORF_CCNF | 73 | 22 | 17377 | 2626 |
PHF10,HMGN4,SIGMAR1,MKI67,NKRF,BMS1,BRCA1,CCNF,CDK11A,PDXDC1,FANCI,MFN2,TAF2,RAP1A,SEC23IP,TPP2,GTSE1,ANP32E,WDR62,PPP5C,CPSF4,CAMK2G |
| 8.431e-04 | -7.08 | cytosolic part | cellular component | GO:0044445 | 250 | 56 | 18223 | 2701 |
RPS15,RPS2,TSC2,RPLP2,RRM1,RPL15,EIF2AK4,MCTS1,CFLAR,RPL23A,RPL11,PSMD2,PSMD1,RPL17,UCHL5,ADCY9,RPL19,RPL22L1,ADCY7,CCT2,RPL29,UBQLN4,RPL35,RPL6,RPL8,RPL38,RPS10,RRM2,RPS24,EIF2A,RPL27A,RPS9,ERC1,CCT8,FADD,RPSA,BBS12,RPL36,PI4K2A,PSMC4,RPL37,GEMIN5,TSC1,IDE,RPL32,PRDX3,RPS27A,RPS14,HPS5,GUCY1B1,EIF2D,RPLP1,TICAM1,RPS26,PSMC1,SNAPIN |
| 8.467e-04 | -7.07 | GSE14308_TH2_VS_INDUCED_TREG_DN | MSigDB lists | GSE14308_TH2_VS_INDUCED_TREG_DN | 182 | 44 | 17377 | 2626 |
MIB2,PTMS,NDUFV2,TSC2,ZDHHC8,MAGED1,TRIO,TBC1D13,MYO9B,POMP,QSOX2,NDUFV1,CCNA2,IL6ST,EXOSC1,BUD31,STRAP,POC5,TERF2,ACSL5,TELO2,MLEC,TSTA3,LDB1,CPOX,NUSAP1,ARID1A,ELK1,PEF1,API5,ARL5B,SPPL2B,BTBD1,NECAP2,OPTN,MRPL2,SPATA2,CERS6,DTX4,ACLY,PPP5C,RRS1,CDK2,ZBTB24 |
| 8.467e-04 | -7.07 | GSE17721_0.5H_VS_24H_GARDIQUIMOD_BMDC_UP | MSigDB lists | GSE17721_0.5H_VS_24H_GARDIQUIMOD_BMDC_UP | 182 | 44 | 17377 | 2626 |
DNAJC5,RPLP2,HMGN3,COX4I1,DAZAP2,TWF2,FOXO3,PABPC4,MCTS1,KIFC1,FANCL,GSTK1,ARPC5,TBC1D22A,INTS1,H2AFY,GPATCH1,TPCN1,CSNK1G2,ARHGAP17,HEMK1,PPP1R18,LDHA,KRAS,CDC6,MTX1,SLC50A1,EIF3A,POLR2A,BRMS1,UTP20,TSC1,TMEM41A,NAP1L1,HSPBP1,DHX16,NSMCE2,CDCA5,EXOC4,ATF6,SRSF3,SNRPG,ZMAT3,VPS29 |
| 8.467e-04 | -7.07 | GSE15330_HSC_VS_LYMPHOID_PRIMED_MULTIPOTENT_PROGENITOR_IKAROS_KO_UP | MSigDB lists | GSE15330_HSC_VS_LYMPHOID_PRIMED_MULTIPOTENT_PROGENITOR_IKAROS_KO_UP | 182 | 44 | 17377 | 2626 |
KRBA1,TOR3A,GNE,PXMP2,CSNK1A1,CUTC,HDDC2,PABPC4,CD320,CFLAR,RBM17,NUDT19,NOL11,ATG3,MTA1,BDH1,PARL,YBX1,RNF135,NUP85,TIMM50,EBAG9,PPAN,CCT2,MAPRE2,PSRC1,LACTB,TBRG4,ATXN1,BCLAF1,RAB3IP,NDUFA7,DNAJA1,SOX4,PRMT2,ZFAND5,FAS,TMEM168,CCDC86,SIAH2,AEN,PRMT7,SLAIN1,MAPK1 |
| 8.467e-04 | -7.07 | GSE17721_PAM3CSK4_VS_CPG_12H_BMDC_UP | MSigDB lists | GSE17721_PAM3CSK4_VS_CPG_12H_BMDC_UP | 182 | 44 | 17377 | 2626 |
C19orf53,CDK2AP2,LAGE3,OLA1,TMEM97,NDUFA4,LYRM2,PARK7,MFSD10,WRNIP1,EIF4A3,SLC44A1,NDUFS8,RBM3,CYB5R1,ERI3,RNF26,EIF5,S100A6,ABCC1,PREB,USP34,EIF5A,VOPP1,POLR2G,GALC,EMB,LRBA,WBP1,PRKRA,VDAC1,CYB5A,YIF1A,SEC31A,HINT1,NDUFA11,LRPPRC,MPV17,H2AFX,COX8A,ACADM,LTA4H,PURA,OAZ1 |
| 8.467e-04 | -7.07 | GSE31082_CD4_VS_CD8_SP_THYMOCYTE_UP | MSigDB lists | GSE31082_CD4_VS_CD8_SP_THYMOCYTE_UP | 182 | 44 | 17377 | 2626 |
PWWP2A,PTMS,HECA,KRBA1,KDM4A,ZFP91,CAST,RAB6A,AP1B1,ETS1,RCOR3,PIP4K2A,HMG20A,KIAA1147,FKBP1A,RAP1A,TNPO2,UBE3B,MAML1,CITED2,SLC35A1,HP1BP3,USP34,BIRC3,EID1,LDB1,HSDL1,LNX2,NFATC2,UBE4B,GALNT7,RAB5B,ERC1,DDX17,TSC1,TXNDC16,CHD3,DUSP11,ROCK1,GALNT10,CD81,LRP8,TOB1,ZMAT3 |
| 8.467e-04 | -7.07 | GSE14308_INDUCED_VS_NATURAL_TREG_UP | MSigDB lists | GSE14308_INDUCED_VS_NATURAL_TREG_UP | 182 | 44 | 17377 | 2626 |
TMEM106C,CCNC,SUCLG1,KLC1,ABCB10,IFT27,TMEM165,QSOX2,RPAIN,EDC3,RPL23A,LRRC14,CCNK,THAP4,MECR,NSFL1C,PDCD2,NDUFB9,ATG13,MINPP1,LMAN1,ATP6V0D1,STRAP,NSUN4,MSH6,UBQLN4,NSUN2,SCFD2,USP22,BICD2,AMDHD2,ELK1,ERC1,CLNS1A,MFN2,YIF1A,KIF18A,CLK3,PRDX3,ACLY,TAF12,NDE1,TSTD2,GEMIN7 |
| 8.467e-04 | -7.07 | GSE22611_NOD2_VS_MUTANT_NOD2_TRANSDUCED_HEK293T_CELL_UP | MSigDB lists | GSE22611_NOD2_VS_MUTANT_NOD2_TRANSDUCED_HEK293T_CELL_UP | 182 | 44 | 17377 | 2626 |
GCLM,HJURP,DNAJB2,PRKAA1,STARD7,KLF13,CSNK2A1,PPP3CB,BLM,DUSP22,COPB2,USP5,CD59,RPN1,CTNNBL1,THADA,UCHL5,AKAP8,ANXA5,SUCLG2,SLC12A2,IFT46,TPCN1,TMED2,PPAN,TIMM8B,RBM42,AATF,RPL6,PSMA1,NFATC2IP,PRKRA,COMMD4,TSR2,TRIM28,SNRPA,RDH11,GLOD4,ATAD2,TTC13,YWHAH,LTA4H,UBE2C,RAB3IL1 |
| 8.467e-04 | -7.07 | GSE26343_WT_VS_NFAT5_KO_MACROPHAGE_LPS_STIM_DN | MSigDB lists | GSE26343_WT_VS_NFAT5_KO_MACROPHAGE_LPS_STIM_DN | 182 | 44 | 17377 | 2626 |
RMND5A,NAT9,GGA1,ZFP91,MAN2B1,IKBIP,GGA2,PSEN1,PIP4K2A,TMCC3,DPYSL2,KIF13B,ZNF746,ARHGEF1,HADHB,MAVS,RNF19A,ARL5A,IMPA2,NIPAL3,ANKLE2,RB1CC1,CIC,ZNF512,DENND4C,DCAF8,KIAA0930,PFKFB3,PLEKHM3,NUSAP1,GALK2,CYFIP2,TFEB,PTPRF,PLD3,SGSH,GPS2,RBL1,PRPS2,WDR7,C4orf46,MEGF9,RBBP4,DNAJC30 |
| 8.467e-04 | -7.07 | GSE11057_CD4_CENT_MEM_VS_PBMC_UP | MSigDB lists | GSE11057_CD4_CENT_MEM_VS_PBMC_UP | 182 | 44 | 17377 | 2626 |
HECA,ASH1L,NSMCE4A,LIME1,ABCC10,ANKH,ARFIP2,S1PR2,ABHD14A,DDX56,THAP4,ZNF335,DCP1A,PIK3IP1,MAP3K14,RHBDD2,ABCC1,NIPAL3,VOPP1,ANKLE2,DDX24,PBXIP1,ADSL,LRRC8A,PACS1,ESYT1,NCDN,EPB41,OPTN,ZNF862,SEPT1,HINT1,CHD3,WDR59,LPCAT4,GLG1,PRMT7,USP20,ZFP90,PIEZO1,TMEM14A,LRP8,DDX42,SSRP1 |
| 8.476e-04 | -7.07 | GNF2_BNIP2 | MSigDB lists | GNF2_BNIP2 | 34 | 13 | 17377 | 2626 |
SEC11A,EIF3L,PDCD6IP,GMFG,STAT6,MBD2,ACTR3,NACA,RBM3,DDX5,ADPGK,SSR1,PAPOLA |
| 8.476e-04 | -7.07 | RAB10 (RAB10, member RAS oncogene family) | protein interactions | 10890 | 60 | 20 | 17029 | 2761 |
STAU1,SEPT9,MDH2,RAB7A,TKT,FKBP2,PKM,DUSP22,SDHA,CDC73,APP,OPTN,RPA1,RPA2,RAB8A,AP1S1,TAGLN2,GPI,SYTL3,CFL1 |
| 8.476e-04 | -7.07 | CRNKL1 (crooked neck pre-mRNA splicing factor 1) | protein interactions | 51340 | 60 | 20 | 17029 | 2761 |
SART1,SNRNP200,CDC40,XAB2,SUZ12,PPIE,DHX8,KRAS,EIF4A3,FBXO7,EFTUD2,PPIL2,YJU2,ISY1-RAB43,AQR,SNRPG,SNRNP70,NKAPD1,IFI16,PRPF19 |
| 8.476e-04 | -7.07 | POLR2M (RNA polymerase II subunit M) | protein interactions | 81488 | 60 | 20 | 17029 | 2761 |
FTL,POLR2I,RPRD1A,POLR2G,POLR2L,UBR2,AMD1,POLR2D,BRCA1,POLR2A,WWP2,POLR2J,SIVA1,CEBPG,RPAP1,SSNA1,MYO9A,ANKHD1,RPRD1B,ASB6 |
| 8.476e-04 | -7.07 | MTA3 (metastasis associated 1 family member 3) | protein interactions | 57504 | 60 | 20 | 17029 | 2761 |
TGFB1,PHF20L1,MTA2,RCOR1,CDK13,NOTCH2,RCOR3,MBD3,TCF19,HMG20A,HNRNPA2B1,CDKN2C,TFAP4,KPNA1,CHD3,MBD2,MTA1,RBBP4,ZNF800,HDAC2 |
| 8.478e-04 | -7.07 | PSMB2 (proteasome subunit beta 2) | protein interactions | 5690 | 95 | 28 | 17029 | 2761 |
PLK1,CYLD,PSMA8,PSMB7,PSMA1,PSMG1,POMP,SYVN1,MCM2,PSMB9,PSMB3,UBLCP1,PSMC4,RAD23A,PSMD2,PSMD1,PSMA6,PTEN,UCHL5,PSMD8,PSMD3,RAD23B,FBXO7,YBX1,ASNA1,PSMC1,HRAS,TUBB |
| 8.493e-04 | -7.07 | REACTOME_SIGNALING_BY_FGFR_IN_DISEASE | MSigDB lists | REACTOME_SIGNALING_BY_FGFR_IN_DISEASE | 121 | 32 | 17377 | 2626 |
PDPK1,FGFR1OP,NRAS,TSC2,AKT2,RAF1,PRKAR1B,KRAS,AKT1S1,PRKACA,FOXO3,MAP2K2,MAPK3,PPP2CA,CALM2,MKNK1,FGFR3,MDM2,SHC1,PTEN,RPS27A,MYO18A,ADCY9,STAT1,CDKN1B,CREB1,MAPK1,STAT3,HRAS,FGFR1OP2,ADCY7,MLST8 |
| 8.529e-04 | -7.07 | IRF2 (interferon regulatory factor 2) | protein interactions | 3660 | 32 | 13 | 17029 | 2761 |
PPP3CA,HMGN1,MDM2,FAM208B,CTSS,KAT2A,FOXK1,STAT1,CSNK2A1,BRD7,PPP3CB,PRKACA,APP |
| 8.529e-04 | -7.07 | PNPT1 (polyribonucleotide nucleotidyltransferase 1) | protein interactions | 87178 | 32 | 13 | 17029 | 2761 |
GATC,PDLIM1,PRKCSH,GRSF1,PPA2,MRPL12,NUP107,TBRG4,LTN1,NUP153,RANGAP1,CLTB,TMED2 |
| 8.529e-04 | -7.07 | BRF2 (BRF2, RNA polymerase III transcription initiation factor subunit) | protein interactions | 55290 | 32 | 13 | 17029 | 2761 |
SMAP1,DPM1,SF3B1,DNAAF5,NOC2L,TNPO3,SMPD4,GEMIN4,XPO7,SNAPC4,FANCI,IPO4,TMEM33 |
| 8.529e-04 | -7.07 | CABIN1 (calcineurin binding protein 1) | protein interactions | 23523 | 32 | 13 | 17029 | 2761 |
TFAP4,PPP3CA,UBN1,MEF2A,NFATC2,CABIN1,PPP3CB,MEF2D,AP1B1,H3F3A,ASF1B,HDAC2,POLR2A |
| 8.529e-04 | -7.07 | UBAP2 (ubiquitin associated protein 2) | protein interactions | 55833 | 32 | 13 | 17029 | 2761 |
HSPBP1,KLHL20,PRDX5,CUL3,GORASP2,BRCA1,FUS,TOMM40,VDAC1,FXR1,SCYL2,VPS29,ZFR |
| 8.539e-04 | -7.07 | GO_PROTEIN_STABILIZATION | MSigDB lists | GO_PROTEIN_STABILIZATION | 126 | 33 | 17377 | 2626 |
ZBED3,USP7,ZNF207,PPIB,PHB2,CREBL2,PARK7,NAPG,PDCD10,PTEN,PIN1,GTSE1,CREB1,IFT46,MORC3,CDC37,CCT2,TELO2,VHL,GTPBP4,SYVN1,SOX4,CCT8,HSPA1B,TSC1,GOLGA7,PML,SEL1L,DVL1,CLU,CHEK2,CDKN2A,USP13 |
| 8.609e-04 | -7.06 | endometrium-carcinoma-endometrioid_carcinoma | COSMIC cancer mutations | endometrium-carcinoma-endometrioid_carcinoma | 16168 | 2443 | 17385 | 2587 |
HECA,ZBTB10,ABCC10,HEXB,TGOLN2,CCNL2,FBXO22,EEF2K,THAP4,RAD23B,ATP13A3,DNM2,FTSJ3,USP34,CCDC57,ERCC1,NRAS,EHMT1,KIF15,HNRNPF,WDHD1,MIER2,DIDO1,RAB22A,SMAD2,MID1IP1,RPS27A,MYO18A,OGT,MPV17,COX5A,SMAD1,ZNF75A,ANXA11,SLC25A33,ZNF720,SEC61G,GGA1,MUM1,CCZ1,TRIO,RAB23,KCTD17,HAUS4,EIF2AK4,APH1B,PARN,CDC73,MYL6B,ATG4A,TMEM179B,ERV3-1,SMC3,C4orf3,GEMIN4,MVP,NUP85,PPP6R1,PABPC1,NSUN4,PPA1,IFRD1,AGGF1,FOXK1,RBM42,GTPBP4,MAP7D1,MRPL16,ELK1,EIF4H,RDH11,MAGED2,KPNA1,ETS2,TYW5,WIPI2,RUFY3,PDLIM5,ACSF2,FAM72D,RHOG,EXOC3,STARD7,C5orf30,VTI1A,SLC35B2,INO80E,LCLAT1,RCOR3,CPNE3,KIAA1147,RBM23,ZNF420,AHCTF1,TBC1D22A,TBC1D14,GMEB1,NSFL1C,SEPT11,GPD1L,ZC3H3,PDCL3,SNX8,ERMP1,EID1,IDH3A,POLR2D,HTATIP2,MEF2D,TMEM147,GSTCD,TANC1,MAT2A,VPS26B,NSMCE2,CORO1C,CAMKMT,PPP5C,PITRM1,TUBB,COMMD10,ZNF445,HABP4,CCM2,FLOT1,BTN3A1,ATG2B,ABHD14B,PPP1R3B,GOLM1,ZBTB45,HUWE1,ZNF260,NAA50,ANXA5,LTN1,UBE3B,NAP1L4,ZNF710,ST8SIA2,RPL22L1,MED22,SPTAN1,STAU1,DDX24,TCTEX1D2,TACC1,MRS2,LDHA,HEBP2,LLPH,RAB3IP,TTC33,PICALM,SH3BP5,SLC19A1,ACOX1,FAM3C,AEN,PARP10,YWHAH,THAP5,GPATCH4,FAM129A,TRIM11,YTHDC2,SNX15,RBM8A,ENSA,NENF,SND1,RUFY1,TRIM65,ZER1,PRNP,KRR1,RAB8A,NUP210,NT5DC1,NOC2L,EIF5,TACC3,RYBP,VPS13B,PTPN18,MIOS,MBLAC2,SNRPB,CDC6,UTP3,PBRM1,ODC1,USP21,TRAM2,FBXO28,BCL7C,ARRDC1,ADAM9,DVL1,NUMB,ZNF564,C1orf74,CTU2,PARP12,ZCCHC9,CENPF,LAMTOR3,CHCHD2,NCKAP1,LYRM2,RSAD1,TNS3,SUB1,RINL,SSBP3,KIF13B,MBD2,XPA,AHCY,RBM3,GLE1,MRPL48,LRSAM1,HDHD2,NTPCR,NSDHL,AMD1,CAMSAP1,ZNF761,METTL22,ICAM2,STYXL1,APPL1,BBS12,RXRB,SDHB,PCM1,GALNT2,TMEM168,NLRC5,BTBD10,MYO9A,CCNB2,USP7,GLT8D1,RPLP2,SUCLG1,ARID2,TMX4,SLC2A1,ATP6V1B2,PCBP1,LYN,BCAP31,VAV1,TMEM69,MRPL50,PSMA6,ZNF473,ZNF302,BRPF3,TARDBP,BCAP29,CTDSP2,PRPF19,PPIF,KDM3B,MND1,CLCN3,BIRC3,RAB7A,ANKRD33B,PPIE,CHMP2B,VDAC1,EIF3H,TMEM201,GLOD4,IDE,DHX16,UHRF2,XRCC3,CHMP4B,PARD3,BCL2L12,C19orf53,KLHL21,PDAP1,TMX3,CDCA8,GTF3A,ARF1,SLC12A9,TUBGCP2,DNAJB9,HOMER1,POLR1B,RNF5,RBM15B,PPAN,RHOA,RPRD1A,BTAF1,TOP3A,ARHGEF12,PCGF1,DDX23,RAB18,CACNB1,TRIM26,PDCD6,ATP6V1D,L3MBTL3,FAM110A,NEIL3,CTBS,BBX,IMPDH1,TAF12,NR2F2,PGAM1,HIPK3,IFI16,NUP188,TXN,H2AFZ,PNISR,PRKCSH,USP39,UBE2I,SLC25A37,ASPHD2,ZNF428,RAB4A,TRA2B,SUCLG2,CISD2,TAF5L,ZNF800,CDC5L,ZNF524,SGCE,OSBP2,NSUN2,USP22,CLNS1A,EIF3A,ZMYM3,DOT1L,IWS1,ANKRD10,WAS,KIF18B,TPP2,C1orf109,ZMAT3,B4GALT2,PRPF38B,RECQL,C9orf78,EWSR1,GADD45G,RRM1,ACAP1,B4GALT1,CYCS,SUPT7L,TMEM165,NPLOC4,CNOT3,SPAG5,WDR48,RTKN,CEP104,EXOSC7,KLHL5,LRRC8D,MSH2,PIGG,OSTF1,FBXL7,MRPL40,TNRC18,SYTL3,FAM171A1,APOL1,EIF5A,GCC2,PRIM2,ELL2,RDH10,MFNG,RPS24,GORASP2,CAPZA2,ADRB2,CCT8,MTR,PHF6,PFDN5,SLCO4A1,TTC13,GOLGA2,RBMX,MED15,PIAS2,APPL2,SAMD8,NUDT3,CDKN2A,ZNF511,ATXN3,RAF1,KIAA0232,C2orf49,CD320,EPM2A,CCNA2,MTMR4,BRI3,TP53BP2,AQR,RBM12B,ILKAP,CDK12,SAP30,BRD4,DRAP1,NARF,LRRC8A,ELP4,ABHD11,PKMYT1,ASB13,SERP1,TRIM28,SUPT16H,EIF3K,CHMP4A,CBWD1,ATF6,XRCC4,ADAM23,PRPF4B,NDUFS1,DEPDC1,MECP2,SECISBP2,HMG20A,WWP2,JAKMIP1,SLC25A36,CCNK,DNAJC8,AXIN2,JMJD4,ANKRD37,KAT2A,TMEM126B,RABIF,ADSL,PACS1,BMS1,KCNQ1,OTUD3,ARSK,MACF1,KIF11,COMMD4,KLF6,SMAP2,FADD,SH3GLB1,MYO1F,CBX3,TMEM127,INF2,DUSP11,DDX5,WDR62,TAF6,ESPL1,DDB1,DEF6,FAM83G,IPO4,UBL3,NAT9,PIGM,LYRM4,GPR132,UBE2Q1,PTP4A3,BRIX1,MRPL19,ZNF696,SF3B2,PCYOX1L,CDC42,SYNM,GOT2,JAZF1,HADHB,RPF2,SLC35C2,CNNM3,CARM1,SRPK2,WDR41,LARS,ZCCHC10,CCDC138,LRBA,TMEM216,SUMF2,KMT2C,OGFR,PRPSAP1,ASF1B,RPL37,MAN2A2,EIF4ENIF1,NIP7,U2SURP,MIA2,ZNF268,VPS4A,PPP1R2,PM20D2,XPNPEP3,RGS2,LYAR,POLR2I,TRAFD1,SUGP2,GBA,EIF2A,SYVN1,CCDC71L,DAPK3,ARHGAP15,MASTL,UAP1,NFIL3,FN3KRP,YWHAZ,CTSA,TMEM14A,TOB1,TSEN15,ADNP2,TCF12,PRKAB1,MDH2,SMARCA4,ORC1,RRN3,UBXN2A,IARS,CD3EAP,KIF14,EXOSC1,CS,CLTB,CSTF1,POU2AF1,UBQLN4,NXT1,HPDL,PGGT1B,SELPLG,SMU1,ATXN1,GLO1,OGDH,BICD2,CADM1,EDEM2,HERPUD2,TOLLIP,FANCE,MBD3,PDHX,RPS9,ALKBH6,SURF4,DUS3L,ARNTL,ANP32E,FKBP5,TMEM101,CCDC125,ABCA1,PDCD2L,GCLM,RAE1,DCTN2,NUP54,CHIC2,PAWR,MXD4,DCUN1D4,PIP4K2A,XPR1,FERMT3,KIF5B,KLHL20,SEC24C,RRBP1,ARHGEF2,ANP32A,LDLRAD3,STAT3,MYO5A,NIPAL3,TXNL1,PHF20L1,DCAF6,FAM49B,TMEM39A,ATP2C1,RFFL,COG1,RCOR1,PRMT2,TFEB,LEMD2,UPF1,ELMO1,ZC3H7B,DTX4,ZMIZ1,TERF1,HRAS,CCDC93,TMED7,PIGQ,CNTROB,PPP1R16B,MIS12,GSDMB,TTC9C,PDS5B,NUP153,PGAP2,TMEM115,PLEKHM3,DCUN1D5,PLEKHF2,BRMS1,PWWP2B,TRIM47,WDR11,AXIN1,SMG9,TRIM52,LONP2,NDUFV2,PHF23,CERK,SLC4A2,EZH1,ITGB5,LMNA,MCTS1,DDX56,EIF2S2,SLC38A5,FOXN2,CARS2,PRRC2A,C16orf72,RB1CC1,ZMYND11,PGS1,MYBL2,UHRF1BP1,MPG,MATR3,CYB5A,NCDN,POLR2J,SETD3,TEX30,PTAR1,CNOT6,NDE1,EGLN1,ZNF207,ANKRD27,ABCA3,SARNP,IVNS1ABP,RMI2,MON1B,TMEM97,NIT2,NUF2,ZNF267,TMEM161B,APP,PRKD3,CLUAP1,ATP2A2,UTP18,GRSF1,DUT,ZCCHC2,ANAPC7,RNF19A,FAM76B,TMEM9,GCC1,RNF169,ADCY7,ATP6V1G1,ENPP4,RNPS1,CDCA2,FKBP3,GPR137,DDX17,CHCHD3,PEX5,CDC16,HIPK2,MBOAT1,TICAM1,PDXK,ZBTB11,ANXA6,TMBIM4,GMCL1,UBE4A,ETS1,WRB,ZNF92,PNO1,CAPN2,ADD3,SUV39H2,TTLL12,TPCN1,TMX1,LYPLA2,HNRNPM,MFSD12,LDHB,PPP3CA,NUDT8,POLK,JTB,EMP3,MTMR12,ZP3,PDE3B,KIF18A,CCDC6,MAPK6,C4orf46,LY75,SLC25A19,RGL1,PSAP,WDR76,IGBP1,FAF1,SNAPIN,COX15,THOC1,AGRN,GNPDA1,GPBP1L1,PPP1R15B,CSNK2A1,EBNA1BP2,GIT2,BIRC2,ATPAF1,DLG5,ABL2,XRCC2,ZFYVE27,MCMBP,PTPRK,CDC37,METTL1,HARS,GMFB,ESYT1,ANLN,RAB5B,RHEB,DPYSL3,TBC1D17,TIMM13,CDCA4,TONSL,NRM,NAGLU,ACTB,ZNF45,TMUB1,CTCF,ASAH1,DOCK11,CRLF3,ASXL2,LRRC14,NUS1,SLC27A4,MDFIC,MAML1,CYTH1,NQO2,UTP15,EIF2AK1,EIF4G2,ZDHHC3,MOSPD3,ITPRIPL1,CDC27,SNAP23,TBPL1,PRMT7,KCTD7,NDUFA5,CYLD,UGP2,DYNLL1,COPE,HCFC1R1,ZADH2,GGPS1,RPAIN,RAD23A,ATP6V0B,PDK2,STRBP,DUS4L,MRPL34,PDCD2,SLC39A9,CLPTM1,RPL29,RPL35,DNAJC9,MTMR6,NFATC2,KDM1B,ARL5B,USP36,CCDC127,MRPL2,ATP1A1,CLK3,PSMD3,MAFK,CEP55,DNAJC17,ZNF436,NCOA1,SLC25A39,ZC3HC1,ZNF146,ATXN7L2,CDC40,GOLIM4,SMAP1,RRP15,DAP,GNE,SMC6,ARFIP2,NKRF,CHAC2,BZW2,WRNIP1,CENPM,PTGES3,CAMK2G,MLEC,ZNF202,PPWD1,FAM50B,RHOT2,TPD52L2,GOLGA7,TWSG1,PGRMC1,GLG1,FAM126A,RPS6KC1,UBE2C,PPCS,NDUFB6,TMEM41B,ZDHHC8,PLXNA1,CCNB1,SLC20A1,COMMD6,ABHD14A,C14orf119,ASAP2,SNUPN,CNPY4,PLCL2,SEH1L,ATG9A,PBK,MKI67,DDX20,AMDHD2,SLC17A5,GALNT7,CCNF,FOXRED1,RBM47,PTER,WDR4,DHTKD1,TRAF5,HDAC2,PWWP2A,HSPH1,MAPRE1,CHTF18,KIF23,SLC35B1,NOTCH2,PMF1,COPG2,JMY,FKBP1A,SLC31A1,SNX18,CTPS1,ATP6V0A2,PIKFYVE,RNF135,LPCAT1,EEF1D,TMED2,PHF10,FTL,DDX28,SIGMAR1,PIP4K2C,FAM133B,RIT1,PLEC,KDM3A,SF3A2,FAS,EPRS,ZNF777,TMEM54,QARS,TCOF1,CABLES1,NRBP1,DNMT3A,RWDD1,CKLF,TRIP10,SF3B1,CAST,SUZ12,RPS6KA1,RAC1,GPR89A,OLA1,SNN,GNB2,FLAD1,APLP2,KDM2A,TNPO2,CDKN1B,TALDO1,GPX4,ATP13A1,MAPRE2,RFC3,ERF,CUL3,SLBP,KIAA1586,H2AFV,POLG2,GAR1,PSMB9,DHX57,NSA2,HSPA4,MRPL55,JAK1,TBL3,GOLGA8A,SEL1L,H2AFX,KLHDC4,B4GALT3,PDCD11,ATMIN,POLQ,POU3F2,OTUD5,NCOR2,ANKRD13D,PKP4,SCAMP3,BABAM1,CDCA3,SLC25A12,BLM,TMCC3,GTF2F1,RPL17,CRAT,AHSA1,PRC1,UPF2,COPS7B,SLC38A10,CNOT6L,CNPY3,IFT46,TSHZ1,ZFP64,DENND4C,DENND1B,WDR18,RPL8,ILF3,LRRC1,RHOT1,TSR2,MARK2,ECH1,PRDX1,PLD3,NUCB1,GNA12,FBXO21,C1orf131,PRDX3,PFDN4,HNRNPH3,STX18,TFDP1,KHSRP,ASNA1,CPEB2,SSSCA1,VPS29,BYSL,S100PBP,MIB2,PTMS,NOP2,UBN1,DCAF15,NF1,FLYWCH2,ALKBH5,MOGS,UBE2Z,TAF6L,MAPK14,BECN1,SNAPC4,RNF103,BCAT2,MBD4,C18orf32,METTL14,ZNHIT6,IMPAD1,RCSD1,PHTF1,SRI,KIF22,ZBTB22,NFU1,OGG1,TRIM14,ELOF1,COPS8,FYTTD1,TRIM8,RRM2,SOX4,ABHD5,UBTF,CXXC4,PAF1,UEVLD,SPATA2,PQBP1,IARS2,ATXN2L,GALNT10,STARD3NL,RPS15,PIGN,AGTRAP,CIB1,XPO7,SRRT,ZNF449,CAPZA1,GLTP,BCL2,KIFAP3,N4BP2,HP1BP3,VOPP1,THNSL1,ISG15,CAND1,C22orf46,GNAS,TSC1,RBM25,CDCA5,ZFP90,NANP,RBBP4,ZBTB24,SMARCD1,MBD1,WASF2,MMACHC,GNPNAT1,MPHOSPH8,HNRNPUL2,CHD1,MEAF6,C2orf68,CCDC50,AKAP8,PARL,RPN2,CHTOP,FAM3A,F2R,SCYL3,ABI1,HTRA2,MOSPD1,RLIM,FAM172A,ZNF500,PSMB7,NLN,WIPF1,BOLA1,BUD13,NDUFB1,PEF1,EIF3G,BTBD1,TAB2,TULP3,WDR59,CANT1,SCARB1,GAS2,USP11,SMURF1,PPP2R2D,TSPAN5,CDS2,MAGEH1,MRPL42,EYA1,MRPS26,LETMD1,HDDC2,RGS1,MAN1A1,FBXO5,GART,PELO,TANK,BRD7,MRPL11,SAMD4B,ZDHHC18,GTF3C6,POLR3GL,WDR81,MEN1,ZNF407,MFN2,COX8A,ZRANB2,MBD6,SRSF3,ATP6V1C1,IDH3B,TATDN1,TSC2,LACTB2,CMTM6,RBM4,ZNF275,ANKRD39,RPL23A,CDKN2C,NAPG,USF1,DNAAF2,MECR,AP1M1,UPRT,CRY2,ECD,MOB1A,RNF26,TIPARP,LRRC59,RHBDD2,MGAT5,BAK1,ZNF559,RHOBTB3,GABPA,WBP1,NUTF2,ARF4,GINS4,KRIT1,BOLA3,AHNAK,RAD18,PDRG1,RNASEL,CHPF2,OAZ1,PDCD4,SMNDC1,NXT2,HIVEP3,KIAA0100,CLSPN,RHOC,DHX9,PDCD7,PSMD9,HAUS2,COPB2,CD59,TFAP4,RNFT1,MEGF8,RIMS3,FBXO7,EFTUD2,CPSF4,MRPL21,LUC7L2,EIF3L,MTA2,TYW1,USP10,ITM2A,SSR2,MTX1,SFXN5,FNTA,PDLIM1,TXNDC16,ZNF830,TMEM159,MRPL3,ALS2,FAM72A,TRIM41,KARS,NQO1,POC1A,ANK3,PTTG1,TPX2,TBC1D13,GLRX3,STMN1,C19orf48,REPS1,ABHD16A,FBXL6,SH3BP1,MTA1,UBA5,CLCN6,INTS12,C8orf59,RPRD1B,SZRD1,CGGBP1,CPNE1,SEC61B,FAM118B,GOPC,E2F3,CIRBP,RPL38,CRNKL1,PFKFB3,GORAB,RAB1A,GIGYF1,TMEM184C,PPP2CA,KIF2A,CCDC14,LSM6,RNF38,SNRPG,CENPBD1,DMWD,USP13,MZT1,ZFP91,TRMT6,IP6K2,WDR5,SLC25A43,IFT27,PMVK,NEIL2,RRP36,SRXN1,RPA2,PSMD2,CLIC4,PDCD10,CBWD2,COQ4,ITGB8,ARF5,ARHGEF1,FBXL19,GTF2H2,TTPAL,UTP20,MAGT1,GPS2,DBI,MRFAP1L1,CD81,TMEM131,WDR13,FANCI,PAPOLA,CREM,TET3,FANCL,GLIS2,IL6ST,INTS1,POP7,SLC44A1,MTPN,ASB6,PLK1,SEPT9,CELSR2,RBX1,RAD51AP1,ZBED5,CKAP2L,PSMG1,UBE2V1,EAF2,IL12RB1,KRTCAP2,LUC7L,LSG1,NECAP2,TRIM4,ALG3,AGPAT2,CHD3,ZNF367,E2F4,PRPF4,KPNA2,BEND6,CLN3,DNAJC30,FAM208A,NGLY1,POT1,MYL12B,CCDC137,RMND5A,HJURP,PHB2,DNAJB2,FAM53C,SDC2,KLC1,CDK13,ADCK5,COX4I1,DNAJB1,RAB6A,ARID1B,C1GALT1,MLX,UBE2Q2,CCP110,ZNF746,ARL6IP1,CTR9,NIPSNAP1,ABHD2,DCAF8,ACSL3,LDB1,MAP4K3,ARMC8,RBM38,NMT2,IRF5,HAUS8,MBIP,COX7A2L,ZDHHC7,SIL1,FAM122A,DTD1,UNC13C,BCCIP,SART1,TRAF7,NDUFAF2,TOR1AIP1,ZNF416,LAGE3,ZFYVE21,TM9SF3,RRAGC,ZNF121,OIP5,NRF1,WDR44,PPME1,EFCAB11,RPAP1,CABLES2,LMAN1,AHCYL1,TOP1MT,STRAP,SPSB3,ZNF583,SNX25,ARHGAP17,ZNF780B,PPT1,NUP155,DCLRE1C,MRPS14,RHBDF2,SUGP1,RBL1,FASTK,UBXN2B,STK38,AP1S1,SPRYD4,SLC22A23,H3F3A,CHID1,SMAD4,RAD51D,SLC30A9,CMAS,UNK,NADSYN1,HMGN3,NCAPG,SCYL2,FZD6,HERC3,GTPBP3,CTSS,ORC3,RNLS,YTHDC1,ACP2,HMGN5,CSRP1,METTL5,ABCF2,TUFM,RANGAP1,PNPLA8,HAGH,API5,ZFR,SEC23IP,E2F1,USP20,RBPJ,PDCD6IP,MAX,GXYLT1,LUZP1,ADAM10,CXXC1,TSC22D3,AP3M2,CUL1,GYG1,NANS,OAT,MYEF2,ANKRD26,PA2G4,NOL11,FIZ1,ZNF200,MARCH2,SLC26A2,SRP72,KLF10,LACTB,RFC2,RAB2B,PRIM1,MAP3K4,HHEX,LUC7L3,MAP4,MRPL27,BTF3,PTPDC1,NMD3,CCDC59,PTOV1,COX5B,DNAJC5,SCOC,DHPS,POLR2K,ANKH,VAV2,PRKAA1,C16orf87,GSPT2,TATDN3,DLGAP4,PRPF39,PSEN1,ZNF79,PDXDC1,VPS25,NDUFS7,YY1AP1,C12orf10,FAM192A,RPN1,LHX8,ARPC5,ZNRF2,TPST1,DAPK1,PIK3IP1,CYC1,SOCS5,FDFT1,PIGT,EMB,WDR1,ZNF574,C1orf35,EXOSC9,ARID1A,PTTG1IP,FXR1,GOSR1,MAP2K2,TWISTNB,AKAP1,XRCC5,HMGN2,PI4K2A,CAT,DERL1,HSPBP1,MTHFD2,CEBPG,ARAP1,USP32,FAM83D,CABIN1,SMPD4,GPI,CYTIP,REPS2,RAB11B,UROD,SLC39A13,POMP,BCL2L1,NUDT19,DECR1,RALB,SIAH1,ADCY9,LPIN2,MRPS27,SOCS6,TTC3,RNASEH2A,CFL1,ANKLE2,CDC123,VDAC2,ERC1,AMZ2,ANKZF1,RAD51C,ZNF282,DSN1,DDOST,HINT1,DGCR8,SAFB,RWDD4,FTSJ1,LMBR1,NCLN,BEND3,EYA2,DYNC1LI2,MANBA,B4GALT5,SLC41A1,FAM76A,TKT,CBLL1,ARGLU1,LANCL1,POFUT1,FAM8A1,HEATR5B,HLA-A,EBP,RFWD3,NDUFA2,FUT8,FJX1,BTF3L4,PTPN11,MRPL54,FEM1B,RPL19,CNN2,NDUFA3,MTX2,MSH6,PDLIM2,LONRF3,RFXANK,FBXO9,GUF1,RPL32,ZHX1,OAZ2,NDUFS5,WDR91,HIGD2A,POLA2,ZNF76,MTX3,COPA,UQCR10,HMGXB3,PHRF1,ABCB10,COMMD5,MAP1LC3B,DST,RAB35,SIVA1,GPATCH1,TCEA1,DRAM2,DEAF1,SNRNP200,LAP3,NCK1,VHL,SREK1,ARHGDIB,PITPNB,HSPB11,BRWD1,PPM1G,SH3GLB2,CRCP,BAZ1B,ACBD4,STK11,CLU,CHEK2,ZSWIM3,TSTD2,CHPT1,MRPL13,DCAF5,CAPN1,UBE2D3,NSMCE4A,PPP1R12A,ZCCHC8,GORASP1,UBXN1,NACA,RPL15,EPN1,PCSK7,THRAP3,QSOX2,TTF1,NUP205,PRPF18,CHKA,DTL,ZRANB1,SLC12A2,ATP6V0D1,CSNK1G3,CREG1,NUDT4,RPL6,VKORC1,SLTM,EVC2,KLHL15,SIAH2,SLC16A1,EHD4,SNRNP70,C11orf1,APOL2,N4BP2L2,CHMP2A,CORO7,FEZ2,PMS2,UCK2,UCK1,CLCC1,EXT2,MXD1,USP5,HNRNPA2B1,SAP130,NVL,PPP6C,CYB5R1,ZNF770,EBAG9,RNF25,PCGF6,METTL2A,FAM72B,PON2,HNRNPR,HPS5,STAT6,MAPK1,BRD9,TMEM33,NAT14,DNAJC2,TRIP12,SHPRH,SCYL1,VPS45,MYO9B,GFM2,SPPL2A,FASTKD3,FGFR3,PPIG,ZDHHC13,TMEM99,H2AFY,ATG13,NDUFS8,ERI3,FBL,SLC35A1,FRMD8,MICAL3,TGFB1,ELOVL5,HEMK1,TIMMDC1,HELB,PSPC1,MIER1,SCFD2,NDRG3,CDK11A,MEGF9,ACAT1,CENPT,PLOD3,RAB3IL1,ZSWIM6,RAB14,ADD1,MRPS15,KDM4A,XIAP,DHX8,GLUD1,ANKRD23,PABPC4,CALM2,CDK5,PSMD1,NEK6,NSRP1,RABGAP1L,SRSF4,FNIP2,KCNAB2,PCBP2,MLST8,PLK3,ZNF672,MRPL43,HSDL1,MCL1,SMC2,PPFIA3,ICMT,SLC50A1,STOML2,LIMK1,ZNF689,PRDX5,ATE1,MLYCD,ATP6V0C,ST3GAL2,FBXL3,E2F2,PFKP,AAAS,DDX42,SSRP1,MRPL9,MRPS2,STRN4,TOP2B,ZNRF3,TMED3,DDRGK1,RAVER2,GNS,INTS7,INPP5A,MCM5,PHF14,ZNF326,UBE2QL1,NAGPA,TIMM8B,ETV3,TSPYL4,TSPAN31,DHX29,TEX10,MAN1B1,RPS10,CBFA2T2,ABCF1,RHOB,LRRC14B,DTWD1,PTPRF,SCARB2,OSBPL11,CCDC86,DUSP3,SLAIN1,MDH1,HEXA,RNF139,SNX14,ZNF296,TRERF1,UBR2,CHD1L,ACTR3,WDTC1,MYH9,CREBL2,NIPA2,PRKACA,SAFB2,ANKIB1,STAM,ARL6IP6,RAB21,SP100,ZKSCAN1,DDA1,NUP107,ANKRD13C,MAVS,CEP63,TMEM136,ATF2,DCTN1,SHOC2,PSRC1,MAP4K4,WBP2,ATP6V0A1,NUSAP1,DNAJA1,TAZ,C19orf54,TAF2,SEC61A1,WDR7,RPLP1,CBLN2,FUS,LRP8,COIL,LRCH1,GALK1,ZNF786,RPS2,SESTD1,TRAK1,JMJD6,SIKE1,AKT1S1,KRI1,FBXO3,ERH,GATC,PPP1R8,PRDM4,GTSE1,GEMIN6,DCP1A,SGCB,IMPA2,NUDC,PDPK1,TK1,GUK1,TNFAIP3,GALC,ZNF512,KIAA0930,MRPS10,DDX39A,RPA1,ZNF180,ZNF862,KEAP1,POLE,TATDN2,PITX1,CAPN7,LRPPRC,PML,HMGB2,USF2,ANAPC4,SRM,DDX47,MCCC1,S1PR2,CDIPT,SEC16A,SSR1,LIN9,PCNA,ZNF639,TRMU,PIK3R2,ETV6,TXLNA,PPCDC,FAM86C1,MYBL1,MRPL32,CCAR1,ABCC5,PBXIP1,BAZ2A,TLK1,MRPL12,EZR,LNX2,LRP5,BRCA1,PRKRA,STX16,EPB41,OPTN,SEPT1,SOCS4,QRSL1,PIEZO1,OSGEPL1,GLCCI1,NUDT11,NAA60,GEMIN7,SEPHS2,LZTR1,RACGAP1,PPP3CB,B4GALT4,RLF,RAPGEF6,SNRNP25,RB1,VASP,MED8,VMP1,PPIL2,MEA1,TIMELESS,AHDC1,ALDH18A1,TMEM8A,ABCC1,PREB,TRAPPC9,AACS,MEMO1,KRAS,RTF1,UBE4B,NFATC2IP,LY6E,ARPC1A,ZNF174,PSMC4,GOLGA4,PALB2,SYNCRIP,PRPS2,NIPA1,TIGD2,RNF114,FOXM1,MRPL39,XAB2,SUMO2,DUSP22,COMMD8,RPL11,CSDE1,MDM2,CORO1A,MINPP1,METTL9,POC5,DVL2,GM2A,PSMA8,COQ10B,CPOX,SLC26A6,CYP20A1,PRPF3,RPSA,SRSF1,DNAJC10,ZNF700,SCAP,PLEKHG4B,TIMM17A,TOMM6,FAU,LTA4H,AP2S1,USP53,INTS2,CTDP1,MIF4GD,CDT1,ARID5A,SUMF1,GGA2,AP3S1,CSNK1A1,RMI1,TFRC,PTPN2,STARD9,GSTK1,NDUFV1,SLC1A4,CWC27,SLC35B4,DDX31,ABCD1,RPAP3,CNTN5,SNX2,ZMYM5,CCDC34,CHCHD6,BSDC1,KPNA4,CDKN2AIPNL,FBXO41,BIRC5,TFE3,SNAP29,CDCA7L,PKD2,ACADM,CHMP7,SAT2,GCSH,ZNF496,TMEM109,TAP1,YTHDF3,NHLRC3,IKBIP,EIF1B,ELMOD2,KIFC1,DBNDD1,CYB5RL,PARPBP,RNASEK,CDC25B,PRADC1,DNMT1,NOL12,ORAI2,USO1,AKT2,NOL8,GNG7,AURKB,MCFD2,SLC25A5,ZFAND5,MAK16,STT3A,TMED10,PSMD8,EIF2D,ITGB1,PTPN7,UQCRH,RRS1,ARRB2,RTN3,ZNF598,SVIP,DDX58,WSB2,PPIB,MUT,HLA-E,NDUFA4,MAN2B1,METTL3,CFLAR,NDUFS4,RNF121,MEX3C,KLF16,HDAC7,DAD1,BDH1,PCYT2,GNAI2,ANKHD1,MORC3,TERF2,KCTD20,SEPT8,DCTD,PKM,TOMM40,PATL1,ADSS,SERTAD2,ZFP92,NSF,DCK,ERGIC3,ACLY,LPCAT4,VCPIP1,YY1,PPP6R3,MAP3K5,PPP6R2,RNF14,CDK2,ZC3HAV1,SYS1,ZBTB37,URB2,EIF3D,MAGED1,KLHL18,ADPGK,SLC25A44,AP1B1,SDHA,PHC2,CRKL,MOAP1,TERF2IP,CYHR1,ZNF75D,SHC1,UCHL5,NAA35,TMBIM1,CCT2,CDKN2AIP,MKLN1,HMGN4,LYRM1,GALK2,CDC23,SHCBP1,AP4E1,PRDM11,VEZF1,PPP2R5A,ACYP1,STAT1,PPA2,TRIM32,C1orf112,TCF3,MRI1,BRAP,AGPAT3,MYNN,SDF2L1,SPR,RAB11A,REEP5,FOXO3,MAD2L2,CCDC28A,RBM17,MAT2B,PTEN,CENPJ,TAGLN2,OSTC,PACS2,NCOA2,SMC4,NEK7,NET1,PARP4,TBRG4,ANAPC2,RPL27A,YIF1A,SGSH,HGS,TTLL4,SLC38A7,MFAP1,CCDC69,BRWD3,ESYT2,SKA3,NPHP4,UBE2E2,HNRNPAB,PLXNC1,ST13,TMEM184B,DNAJC24,ZNF107,KIF2C,SLC29A1,AGFG1,SIRT2,FKBP2,USP48,UBQLN2,SNRPD3,CUTC,EDC3,UBLCP1,ZNF804A,RAP1A,THADA,EIF4A3,ATG3,DPYSL2,PPP1R12C,AKR1B1,JOSD1,RP2,TTC4,TECR,ARID4A,FGFR1OP2,TIMM50,TDP1,DPM1,FOPNL,SLC16A7,SLC25A22,STK17B,DHX15,CHAF1A,GEMIN5,COPS6,SASS6,RPS26,PSMC1,SLC12A7,TBC1D12,TM9SF4,ZNF768,UFC1,MED13L,TIA1,MEF2A,EPHX2,PITHD1,RHBDD1,NFATC3,BANF1,BUD31,ZNF335,YBX1,KNTC1,ACAD8,UBE3C,ZNF189,ALDH9A1,KDELR1,TSTA3,CIC,OXR1,SEPT7,TMEM241,NAP1L1,NSMF,ODF2,EXOC4,KIAA1328,NUP62,PITPNA,NAA20,PTDSS1,MZT2B,PDSS2,C7orf26,TMEM106C,IMMT,ASH1L,CHERP,WDYHV1,PLAGL2,CHKB,IRF3,TWF2,PAIP1,ANKRD28,ANKLE1,FARSA,SAR1A,SCAMP4,APOOL,PDIA6,ACSL5,TOR1AIP2,AZI2,GFER,RAD54B,TMEM41A,DAP3,ZNF317,GADD45B,AKNA,CBX4,KIF3B,GOLPH3L,SH2D3A,CASP6,TOR3A,SRGN,DBF4,MFSD10,SAC3D1,CTNNBL1,YIF1B,CLDND1,TTC17,SLC25A1,GINS1,PAQR6,CSNK1G2,TELO2,ADAM17,HMGN1,NASP,ASPM,PPP1R21,PRKAR1B,SYMPK,TARS,SNRPA,MAPK3,HLA-B,ATAD2,PLAA,ZNF330,OSBPL8,KBTBD7,PREPL |
| 8.613e-04 | -7.06 | - | gene3d domains | 2.130.10.10 | 329 | 74 | 8148 | 1295 |
CORO7,TRAF7,COPA,PLXNC1,WDR13,POC1A,WDTC1,PLXNA1,GNB2,RIC1,UTP18,FBXW2,TAF5L,CORO1A,UTP4,STRAP,SEH1L,PRPF19,CSTF1,WDR41,MLST8,MIOS,LRBA,SMU1,WDHD1,WDR82,EML4,GEMIN5,BRWD1,WDR11,SCAP,HPS5,TBL3,CORO1C,WDR59,WDR4,WDR7,PRPF4,DMWD,PPP2R2D,DCAF5,AAAS,WSB2,CDC40,RAE1,STRN4,WDR5,COPB2,WDR48,RFWD3,DTL,DCAF6,WDR1,DCAF8,WDR18,UTP15,PPWD1,WDR81,EIF2A,ARPC1A,RMC1,SEC31A,PLAA,PALB2,DCAF11,WDR76,WIPI2,WDR91,WDR62,RBBP4,BRWD3,WDR45B,ANAPC4,DDB1 |
| 8.663e-04 | -7.05 | nucleoid | cellular component | GO:0009295 | 43 | 15 | 18223 | 2701 |
DDX28,MTERF1,GRSF1,TWNK,TUFM,VDAC2,HADHB,LRPPRC,ATP5F1B,TOP1MT,VDAC1,MPG,LRRC59,POLG2,SLC25A5 |
| 8.663e-04 | -7.05 | mitochondrial nucleoid | cellular component | GO:0042645 | 43 | 15 | 18223 | 2701 |
DDX28,MTERF1,GRSF1,TWNK,LRPPRC,TUFM,VDAC2,HADHB,ATP5F1B,TOP1MT,MPG,VDAC1,SLC25A5,POLG2,LRRC59 |
| 8.669e-04 | -7.05 | REACTOME_POST_TRANSLATIONAL_PROTEIN_MODIFICATION | MSigDB lists | REACTOME_POST_TRANSLATIONAL_PROTEIN_MODIFICATION | 177 | 43 | 17377 | 2626 |
PIGM,PIGN,GNPNAT1,DHPS,PRKCSH,PIGQ,B4GALT5,MOGS,B4GALT1,SUMF1,B4GALT4,MAN1A1,C1GALT1,RPN1,DAD1,SEC24C,FUT8,PIGG,RPN2,LMAN1,ST8SIA2,MGAT5,PREB,EIF5A,MLEC,PIGT,DPM1,MAN1B1,SUMF2,GALNT7,VKORC1,EDEM2,MCFD2,ARSK,SEC31A,ALG3,GALNT2,DDOST,STT3A,ST3GAL2,GALNT10,B4GALT3,B4GALT2 |
| 8.669e-04 | -7.05 | GSE11864_UNTREATED_VS_CSF1_IN_MAC_DN | MSigDB lists | GSE11864_UNTREATED_VS_CSF1_IN_MAC_DN | 177 | 43 | 17377 | 2626 |
KCTD7,NQO1,ADAM10,UQCR10,CCM2,ZNF416,RACGAP1,PDCD7,PITHD1,REEP5,LIN9,RB1,ZNRF2,MEGF8,FJX1,RP2,MTX2,HTRA2,ABCC5,EBAG9,SPTAN1,NTPCR,MBLAC2,PPP1R21,HSDL1,LNX2,SEPT7,C9orf40,BORA,ZNF407,GOSR1,DDX23,C1orf122,PI4K2A,CHMP4A,ORMDL2,TIMM17A,PTER,PARG,CDCA7L,MRPL27,ARAP1,SNAPIN |
| 8.669e-04 | -7.05 | GSE2770_UNTREATED_VS_ACT_CD4_TCELL_48H_UP | MSigDB lists | GSE2770_UNTREATED_VS_ACT_CD4_TCELL_48H_UP | 177 | 43 | 17377 | 2626 |
WSB2,LYRM4,NUP188,MRPL42,USP39,THRAP3,RUFY1,RSAD1,CCP110,IMPAD1,RCSD1,MRPS27,DDX31,UBE3C,OSTC,MRPL21,RPL22L1,CSTF1,DDX28,ZFP64,KAT2A,TACC1,HPDL,TMEM126B,ILF3,BCLAF1,THNSL1,VDAC1,MTR,PDHX,DOT1L,ABHD5,PPP2CA,DNAJC10,PLAA,BRD2,PFDN4,LSM6,SH3GLB2,PPP6R3,SNX14,AAAS,SLC25A33 |
| 8.685e-04 | -7.05 | Selenoamino acid metabolism | REACTOME pathways | R-HSA-2408522 | 121 | 34 | 10287 | 1696 |
KARS,RPS15,RPS2,RPLP2,RPL15,SECISBP2,RPL11,RPL23A,IARS,RPL17,RPL19,AHCY,RPL22L1,LARS,RPL29,RPL35,RPL8,RPL38,RPL6,RPS10,RPS24,RPL27A,RPS9,RPSA,RPL36,RPL37,EPRS,RPL32,RPS27A,QARS,RPS14,RPLP1,FAU,RPS26 |
| 8.739e-04 | -7.04 | regulation of microtubule cytoskeleton organization | biological process | GO:0070507 | 171 | 42 | 17256 | 2622 |
CHMP2A,SKA3,PDCD6IP,MAPRE1,CYLD,RAE1,MECP2,POC1A,CDK2AP2,RAC1,PRKAA1,CIB1,TPX2,RGS2,STMN1,SPAG5,SMC3,CENPJ,ARHGEF2,CDKN1B,MCPH1,TACC3,DCTN1,PLK1,RHOA,PSRC1,KAT2A,TAOK1,CAMSAP1,BICD2,BRCA1,CCNF,CHMP2B,KIF11,BORA,HSPA1B,KIF18A,MID1IP1,NUP62,CHMP4B,XRCC3,GEN1 |
| 8.759e-04 | -7.04 | GO_REGULATION_OF_CYCLIN_DEPENDENT_PROTEIN_KINASE_ACTIVITY | MSigDB lists | GO_REGULATION_OF_CYCLIN_DEPENDENT_PROTEIN_KINASE_ACTIVITY | 92 | 26 | 17377 | 2626 |
BCCIP,PLK1,CCNC,ADAM17,PSRC1,TNFAIP3,CUL3,GTPBP4,CDC6,CCNL2,PKMYT1,MEN1,BLM,TFAP4,CCNK,CDKN2C,HHEX,CCNA2,PTEN,FBXO7,CDKN1B,PKD2,NR2F2,UBE2C,CDKN2A,CDC37 |
| 8.763e-04 | -7.04 | ribosomal large subunit assembly | biological process | GO:0000027 | 30 | 12 | 17256 | 2622 |
PPAN,DDX28,NOP2,WDR18,RPL6,RPL38,RPF2,RRS1,BRIX1,MRPL11,RPL23A,RPL11 |
| 8.770e-04 | -7.04 | protein-DNA complex subunit organization | biological process | GO:0071824 | 266 | 60 | 17256 | 2622 |
HJURP,UBN1,ARID2,SHPRH,CDT1,CENPF,CHD1L,SMARCA4,CTCF,TAF6L,MIS12,OIP5,RPA2,RRN3,XPA,RAD23B,XRCC2,H2AFY,ANP32A,CENPM,NAP1L4,ORC3,SMARCE1,GTF2H2,HP1BP3,NASP,RBX1,TSPYL4,BAZ2A,WDR18,ARID1A,PBRM1,MCM2,ASF1B,CENPU,CHAF1A,RPA1,SUPT16H,TAF2,PAF1,UBTF,RAD51C,NAP1L1,BRD2,RPS27A,H2AFX,ANP32E,XRCC3,HMGB2,CABIN1,CENPT,TAF12,H3F3A,RBBP4,TAF6,NAA60,DDB1,IPO4,RAD51D,SMARCD1 |
| 8.776e-04 | -7.04 | XPC (XPC complex subunit, DNA damage recognition and repair factor) | protein interactions | 7508 | 73 | 23 | 17029 | 2761 |
USP7,MECP2,CHD1L,SDC2,TOP2B,UBE4B,CHAF1A,RPA1,RAD23A,SUPT16H,ZNF428,RPA2,MDM2,BANF1,RAD23B,XPA,H2AFX,H2AFY,WDR76,SMAD1,USP11,DDB1,SSRP1 |
| 8.776e-04 | -7.04 | XPO5 (exportin 5) | protein interactions | 57510 | 73 | 23 | 17029 | 2761 |
PPP3CA,PPP1R12A,HARS,NSUN2,ILF3,PTP4A3,RAB11A,FADD,MAT2B,GSTK1,PFDN5,NEK6,DUS3L,RALB,UCHL5,PPME1,WDR4,EFTUD2,NUP153,CLN3,PDIA6,SMAD4,CDC5L |
| 8.784e-04 | -7.04 | GO_MACROAUTOPHAGY | MSigDB lists | GO_MACROAUTOPHAGY | 262 | 59 | 17377 | 2626 |
PRKAB1,TOMM20,TMEM203,MRPS2,DYNLL1,PRKAA1,ALKBH5,LAMTOR3,RAB23,RRAGC,ATG2B,BECN1,MAP1LC3B,PSEN1,ATG4A,RFWD3,FANCL,MEX3C,SLC1A4,ATG3,DNAAF2,RIMS3,TXLNA,ANXA5,NDUFB9,ATG13,C8orf59,PACS2,ZNF189,CDC37,MLST8,ATG9A,RB1CC1,TMEM39A,SNRPB,RAB7A,CRNKL1,MRPS10,KCNQ1,TOMM40,RAB1A,VDAC1,RHEB,MFN2,OPTN,PI4K2A,MTMR3,RPS27A,SNAP29,TOMM6,COX8A,SLC25A19,MDH1,WIPI2,CLN3,SMURF1,SNX14,PFKP,SNAPIN |
| 8.791e-04 | -7.04 | GTP binding | molecular function | GO:0005525 | 366 | 79 | 17224 | 2647 |
RHOG,RAB14,RAB11B,RAC1,OLA1,TPX2,RRAGC,GLUD1,EFL1,RAB21,RAB8A,RAP1A,CDC42,SAR1A,RALB,RAB35,RAB4A,DNM2,UPRT,SEPT11,SUCLG2,RP2,EIF5,ARL5A,RHOBTB3,NRAS,SEPT9,CGAS,RAB7A,RAB1A,ARL5B,RAB5B,RAB22A,LSG1,RAB2B,ARF4,RHEB,DAP3,SEPT1,RAB24,GUCY1B1,TUBB,RHEBL1,ANXA6,RHOC,GSPT2,RAB23,ARFIP2,RAB6A,ARF1,IFT27,RAB11A,GFM2,RTKN,GTPBP3,ARF5,EFTUD2,DAPK1,GNAI2,RHOA,NOA1,TUFM,GTPBP4,SEPT8,BMS1,KRAS,RIT1,RHOT1,SEPT7,GUF1,RHOT2,RHOB,MFN2,GNAS,ADSS,GNA12,RAB18,EHD4,HRAS |
| 8.794e-04 | -7.04 | TTGCACT,MIR-130A,MIR-301,MIR-130B | MSigDB lists | TTGCACT,MIR-130A,MIR-301,MIR-130B | 372 | 79 | 17377 | 2626 |
SNX27,HECA,CYLD,C5orf30,AGFG1,USP48,ATP6V1B2,LCLAT1,ANKRD28,PRKD3,KDM2A,DPYSL2,SLC44A1,SOCS6,DNM2,TARDBP,MARCH2,ZNF800,ABCC5,TIMP2,BAZ2A,CUL3,ATXN1,PFKFB3,SOX4,RAB5B,ZNF282,MID1IP1,BRWD1,FBXO28,SPATA2,FASTK,MAP4,RNF38,OGT,NCOA1,LRP8,ABCA1,POU3F2,ZFP91,B4GALT5,MECP2,HABP4,PRKAA1,KLF13,ARGLU1,ASXL2,JAKMIP1,MAT2B,KLHL20,BTF3L4,MDFIC,PIK3IP1,MAP3K14,MAML1,PPP6R1,SMC4,SOCS5,MLEC,SNX2,WDR1,BTAF1,MIER1,MEMO1,ARHGEF12,MTMR12,RHOT1,APPL1,AKAP1,TSC1,PLAA,CSNK1G1,USP32,SLAIN1,CNOT6,PSAP,PPP6R3,PPP6R2,NIPA1 |
| 8.822e-04 | -7.03 | regulation of mitotic spindle organization | biological process | GO:0060236 | 38 | 14 | 17256 | 2622 |
PLK1,CHMP2A,PSRC1,SMC3,PDCD6IP,RAE1,TPX2,NUP62,CHMP4B,CHMP2B,BORA,TACC3,DCTN1,HSPA1B |
| 8.841e-04 | -7.03 | GO_FORMATION_OF_TRANSLATION_PREINITIATION_COMPLEX | MSigDB lists | GO_FORMATION_OF_TRANSLATION_PREINITIATION_COMPLEX | 19 | 9 | 17377 | 2626 |
EIF3K,EIF3L,EIF3D,EIF2D,EIF4H,EIF3G,EIF3H,EIF3A,MCTS1 |
| 8.841e-04 | -7.03 | REACTOME_CITRIC_ACID_CYCLE_TCA_CYCLE | MSigDB lists | REACTOME_CITRIC_ACID_CYCLE_TCA_CYCLE | 19 | 9 | 17377 | 2626 |
SDHB,SUCLG1,MDH2,IDH3A,CS,SUCLG2,OGDH,IDH3B,SDHA |
| 8.841e-04 | -7.03 | REACTOME_ABORTIVE_ELONGATION_OF_HIV1_TRANSCRIPT_IN_THE_ABSENCE_OF_TAT | MSigDB lists | REACTOME_ABORTIVE_ELONGATION_OF_HIV1_TRANSCRIPT_IN_THE_ABSENCE_OF_TAT | 19 | 9 | 17377 | 2626 |
CTDP1,POLR2I,POLR2J,POLR2G,POLR2L,POLR2K,POLR2D,POLR2A,GTF2F1 |
| 8.841e-04 | -7.03 | REACTOME_APC_C_CDC20_MEDIATED_DEGRADATION_OF_CYCLIN_B | MSigDB lists | REACTOME_APC_C_CDC20_MEDIATED_DEGRADATION_OF_CYCLIN_B | 19 | 9 | 17377 | 2626 |
CDC16,CDC27,RPS27A,ANAPC2,ANAPC7,CCNB1,CDC23,UBE2C,ANAPC4 |
| 8.864e-04 | -7.03 | GSE41867_DAY6_VS_DAY15_LCMV_ARMSTRONG_EFFECTOR_CD8_TCELL_DN | MSigDB lists | GSE41867_DAY6_VS_DAY15_LCMV_ARMSTRONG_EFFECTOR_CD8_TCELL_DN | 172 | 42 | 17377 | 2626 |
MBD1,ZBED3,PRKAB1,BABAM1,SLC2A1,PTTG1,UBE2I,WRNIP1,DDX56,NRF1,RAB8A,PPIG,MBD2,UBA5,CTR9,NAP1L4,CNPY3,TNRC18,SLC25A1,ANKLE2,DEAF1,NXT1,FAM118B,GOPC,KCTD20,MAP7D1,PRPF3,TMEM147,UTP3,CADM1,RAB5B,IWS1,AHNAK,SEPT1,FBXO28,MAP4,MPV17,PPP6R3,BTBD10,CCDC125,RTN3,HRAS |
| 8.864e-04 | -7.03 | GSE20727_CTRL_VS_H2O2_TREATED_DC_DN | MSigDB lists | GSE20727_CTRL_VS_H2O2_TREATED_DC_DN | 172 | 42 | 17377 | 2626 |
CCDC93,ZBTB10,CDC40,MANBA,ANK3,PCSK7,SMC6,MEF2A,TGOLN2,DOCK11,ETS1,RUFY1,RAB11A,GIT2,KIAA1147,SLC25A37,PCYOX1L,ADD3,NEK6,TNFAIP8,THADA,RALB,PHF14,LPIN2,BTF3L4,ARHGEF2,AHDC1,PIK3IP1,TOP1MT,CNPY3,TERF2,KAT2A,ASB13,TFEB,PFDN5,L3MBTL3,HNRNPH3,LRPPRC,ACTB,MYO9A,ZC3HAV1,NUDT3 |
| 8.864e-04 | -7.03 | GSE2770_TGFB_AND_IL4_VS_TGFB_AND_IL12_TREATED_ACT_CD4_TCELL_48H_UP | MSigDB lists | GSE2770_TGFB_AND_IL4_VS_TGFB_AND_IL12_TREATED_ACT_CD4_TCELL_48H_UP | 172 | 42 | 17377 | 2626 |
NAT9,THOC1,SHPRH,PIGQ,KCTD17,AGPAT1,MEF2A,GMCL1,TBC1D13,HCFC1R1,VPS25,MYL6B,MAD2L2,FANCI,PIP5K1C,C12orf10,KRI1,RBM34,SSBP3,RPAP1,COPS7B,ACAD8,TECR,FTL,ZNF559,RAB7A,MRS2,SCFD2,PRPF3,RAB5B,ERC1,GINS4,RPL36,PRDX3,SNAP29,PTER,IARS2,ZFP90,ATF6,ACSF2,VPS29,SNAPIN |
| 8.867e-04 | -7.03 | MAPK14 (mitogen-activated protein kinase 14) | protein interactions | 1432 | 245 | 59 | 17029 | 2761 |
MAX,FLYWCH2,CDT1,TPX2,CSNK2A1,MEF2A,CDK13,BCL2L1,MAPK14,MYEF2,YY1AP1,EEF2K,PHC2,RB1,SHC1,RALB,PPIL2,PTPN11,BCL2,KIF22,NUP153,CDC25B,CREB1,ATF2,SLC12A2,F2R,HTRA2,CSNK1G2,FOXK1,ERF,MAPKAPK3,WDR1,GMFB,GORASP2,ADRB2,MEF2D,DCUN1D5,SRSF5,LRRC1,SUPT20H,ELK1,KMT2C,TOLLIP,GFER,MAPK3,ADSS,MKNK1,TSC1,TAB2,CCDC14,LIMK1,PPM1G,STAT1,PTPN7,PML,ATF6,USP11,MAPK1,SNAPIN |
| 8.867e-04 | -7.03 | BDNF-TrkB Signaling | WikiPathways | WP3676 | 33 | 13 | 5312 | 837 |
HOMER1,TSC1,MKNK1,NRAS,SHC1,TSC2,RPS6KA1,KRAS,CREB1,MAPK1,HRAS,RHEB,EEF2K |
| 8.875e-04 | -7.03 | SSR3 (signal sequence receptor subunit 3) | protein interactions | 6747 | 56 | 19 | 17029 | 2761 |
RPLP2,PRRC2A,ASPM,ERLIN1,SF3B1,VDAC2,COX4I1,SND1,SEPT7,VDAC1,DDX39A,SSR1,RPN1,BABAM2,MAGT1,DDOST,SEC61A1,PRMT7,XRCC3 |
| 8.875e-04 | -7.03 | MRPL53 (mitochondrial ribosomal protein L53) | protein interactions | 116540 | 56 | 19 | 17029 | 2761 |
PPIF,PPIB,MRPL9,BABAM1,MRPL12,RPL38,TPX2,UBE4B,XPNPEP3,UBE2I,SPR,APP,MRPL50,KIF2A,SUGP1,RRBP1,PQBP1,NABP2,RBMS1 |
| 8.891e-04 | -7.03 | CCT6A (chaperonin containing TCP1 subunit 6A) | protein interactions | 908 | 205 | 51 | 17029 | 2761 |
CYLD,POC1A,SF3B1,ACTR3,WDTC1,ARF1,GNB2,CDC73,USP5,CDK5,RFWD3,RPN1,SHC1,HUWE1,AHSA1,ZNF746,RPAP1,SUCLG2,CRY2,TECR,EEF1D,PDCL3,NIPSNAP1,CDC5L,LDHB,MOB4,CCT2,VHL,IDH3A,CUL3,BRCA1,DNAJA1,MCM2,CDK11A,CCT8,RPSA,PPP2CA,KPNA4,ATP1A1,SMAD2,CAMKMT,DCAF11,XRCC3,PRPF4,FUS,CDK2,ARRB2,IGBP1,SMURF1,DCAF5,PPP2R2D |
| 8.898e-04 | -7.02 | RWD | prosite domains | PS50908 | 10 | 6 | 12060 | 1670 |
EIF2AK4,RWDD1,RNF14,WDR59,RNF25,RWDD4 |
| 8.902e-04 | -7.02 | GO_PURINE_CONTAINING_COMPOUND_METABOLIC_PROCESS | MSigDB lists | GO_PURINE_CONTAINING_COMPOUND_METABOLIC_PROCESS | 361 | 77 | 17377 | 2626 |
NDUFA5,COX15,DNMT3A,PPCS,NDUFB6,UQCR10,OLA1,ADPGK,SLC35B2,ATP6V1B2,ADCY9,PPCDC,NDUFB9,SLC26A2,AHCYL1,DNMT1,OGG1,ADCY7,ENPP4,ATP6V0A1,PFKFB3,NDUFA7,OGDH,ICMT,NDUFB1,TAZ,MAT2A,STOML2,HINT1,NDUFA11,MLYCD,COX5A,DHTKD1,UQCRH,PFKP,NDUFV2,COX5B,GALK1,NDUFS1,MECP2,MRI1,NDUFA4,ABHD14B,CYCS,COX4I1,NDUFS7,NDUFS4,MAT2B,NDUFV1,GART,NDUFA2,NDUFB4,ATIC,MSH2,ATP6V0A2,AHCY,NDUFS8,CYC1,NDUFA3,AMPD2,TGFB1,GUK1,AMD1,LDHA,ADSL,MPG,PDE3B,HSPA1B,ADSS,CAT,DCK,COX7A2L,COX8A,IMPDH1,GPI,NDUFS5,PGAM1 |
| 8.927e-04 | -7.02 | CREIGHTON_ENDOCRINE_THERAPY_RESISTANCE_4 | MSigDB lists | CREIGHTON_ENDOCRINE_THERAPY_RESISTANCE_4 | 273 | 61 | 17377 | 2626 |
COX15,MRPL9,LYRM4,GNPDA1,MDH2,LAGE3,MED13L,HMGN3,CCNB1,C2orf49,APH1B,MAD2L2,DLG5,LYAR,APLP2,PRKD3,ADD3,SLC1A4,ADCY9,SRI,BCL2,AFF1,MAVS,SLC26A2,TECR,MYBL1,TIPARP,C12orf75,DVL2,FDFT1,SAP30,ELOVL5,RHOBTB3,RPRD1A,CELSR2,KAT2A,SIGMAR1,METTL5,PARP4,RFXANK,PSMG1,EMP3,NLN,SLC25A22,CADM1,RHBDF2,CYB5A,SH3BP5,NSA2,SERTAD2,HSPA4,PPP2R5A,PDLIM1,LSM6,RBMX,SIAH2,DHTKD1,FKBP5,RUVBL2,PDCD4,BYSL |
| 8.935e-04 | -7.02 | Signaling by NOTCH | REACTOME pathways | R-HSA-157118 | 112 | 32 | 10287 | 1696 |
MIB2,CCNC,NCOR2,ADAM17,KAT2A,ADAM10,RBX1,APH1A,AGO2,E2F3,MFNG,CUL1,B4GALT1,RAB6A,NOTCH2,APH1B,POFUT1,ATP2A2,RPS27A,HDAC7,TFDP1,E2F1,DTX4,SEL1L,RBPJ,CREB1,TFDP2,MAML1,ARRB2,NUMB,HDAC2,TMED2 |
| 8.935e-04 | -7.02 | positive regulation of ubiquitin-protein transferase activity | biological process | GO:0051443 | 34 | 13 | 17256 | 2622 |
PLK1,RPS2,GOLGA2,PTEN,GORASP1,PIN1,AXIN1,TOPORS,DCUN1D5,RAB1A,DCUN1D4,UBE2C,FBXO5 |
| 8.935e-04 | -7.02 | protein deglycosylation | biological process | GO:0006517 | 34 | 13 | 17256 | 2622 |
MAN2A2,RPS27A,MAN1B1,SEL1L,MAN2B1,SYVN1,EDEM2,NGLY1,PARK7,RNF139,RNF103,RNF5,MAN1A1 |
| 8.958e-04 | -7.02 | BCL2L1 (BCL2 like 1) | protein interactions | 598 | 109 | 31 | 17029 | 2761 |
PLK3,PLK1,BAK1,BCL2L12,ATXN3,DYNLL1,RAF1,MCL1,BCLAF1,CYCS,BCL2L1,VDAC1,PSEN1,MAPK14,BECN1,EDRF1,BCAP31,PARK7,CFLAR,GLOD4,MOAP1,PLD3,ZHX1,SIVA1,UHRF2,BCL2,ACTB,CLU,TP53BP2,CAPN1,CDKN2A |
| 8.959e-04 | -7.02 | coated vesicle membrane | cellular component | GO:0030662 | 170 | 41 | 18223 | 2701 |
TMED7,DNAJC5,COPA,HLA-E,COPE,SCYL1,VTI1A,TGOLN2,TMED3,AP1B1,SEC16A,SYNRG,COPG2,TFRC,HLA-A,COPB2,CD59,SAR1A,SEC24C,RAB35,AP1M1,AP2B1,CLTB,LMAN1,TMED2,KDELR1,USO1,ADRB2,MCFD2,PEF1,PICALM,NECAP2,SEC31A,HLA-B,SCARB2,SEC23IP,PDCD6,SCAP,TMED10,AP1S1,AP2S1 |
| 8.960e-04 | -7.02 | AAAGGGA,MIR-204,MIR-211 | MSigDB lists | AAAGGGA,MIR-204,MIR-211 | 214 | 50 | 17377 | 2626 |
POU3F2,TCF12,RAB14,PRPF38B,TRIP12,SF3B1,ZFP91,SUMO2,MED13L,YTHDF3,ARGLU1,GGA2,MAP1LC3B,CRKL,DLG5,KDM2A,SHC1,CDC42,BRPF3,LRRC8D,FJX1,ZNF335,BUD31,DNM2,SOCS6,BCL2,CDC25B,ATF2,RHOBTB3,BRD4,APH1A,ELL2,C16orf72,BAZ2A,EZR,SOX4,RHOT1,RAB1A,SLTM,AKAP1,ZNF282,CORO1C,PPP3R1,UHRF2,AP1S1,COX5A,RPS6KC1,DCAF5,ANXA11,SSRP1 |
| 9.006e-04 | -7.01 | Fc receptor mediated stimulatory signaling pathway | biological process | GO:0002431 | 73 | 22 | 17256 | 2622 |
WASF2,CYFIP1,NCK1,RAC1,ACTR3,VAV2,WIPF1,NCKAP1,CYFIP2,ARPC1A,LYN,MAPK3,VAV1,WAS,CDC42,ARPC5,ELMO1,LIMK1,PIK3R2,ACTB,MAPK1,ABI1 |
| 9.027e-04 | -7.01 | central_nervous_system-brain-glioma-astrocytoma_Grade_I | COSMIC cancer mutations | central_nervous_system-brain-glioma-astrocytoma_Grade_I | 43 | 15 | 17385 | 2587 |
GNAS,FGFR3,TSC1,NRAS,TSC2,NF1,PTEN,CIC,PTPN11,KRAS,H3F3A,MAP2K2,HRAS,CDKN2A,FUBP1 |
| 9.040e-04 | -7.01 | The oncogenic action of L-2-hydroxyglutarate in Hydroxygluaricaciduria | SMPDB pathways | SMP02358 | 28 | 12 | 992 | 167 |
SDHB,KDM2A,SUCLG1,IDH3A,MDH2,CS,SUCLG2,GLUD1,OGDH,IDH3B,SDHA,MPC1 |
| 9.043e-04 | -7.01 | COPII-coated ER to Golgi transport vesicle | cellular component | GO:0030134 | 89 | 25 | 18223 | 2701 |
TMED7,USO1,HLA-E,VTI1A,TMED3,MCFD2,PEF1,SEC16A,APP,HLA-A,YIF1A,CD59,SEC31A,HLA-B,SEC23IP,PDCD6,GOLGA2,TMED10,SAR1A,SCAP,SEC24C,YIF1B,LMAN1,ECPAS,TMED2 |
| 9.045e-04 | -7.01 | GSE42088_UNINF_VS_LEISHMANIA_INF_DC_24H_DN | MSigDB lists | GSE42088_UNINF_VS_LEISHMANIA_INF_DC_24H_DN | 193 | 46 | 17377 | 2626 |
WSB2,GCLM,TXN,NQO1,TRIP10,SEC61G,DYNLL1,FAM129A,FLOT1,BCL2L1,GLRX3,RPAIN,PNO1,CFLAR,CD59,TNS3,VASP,CLIC4,GART,PSMA6,BUD31,RPAP1,ANXA5,TTC4,TFG,CDC5L,METTL1,WDR1,LYRM1,ATP2C1,GTPBP4,RIT1,NCDN,PRDX1,OPTN,MAP3K4,KEAP1,SEC61A1,ORMDL2,TWSG1,TIMM17A,CANT1,PDXK,PITRM1,NRBP1,BYSL |
| 9.045e-04 | -7.01 | GSE22140_HEALTHY_VS_ARTHRITIC_GERMFREE_MOUSE_CD4_TCELL_DN | MSigDB lists | GSE22140_HEALTHY_VS_ARTHRITIC_GERMFREE_MOUSE_CD4_TCELL_DN | 193 | 46 | 17377 | 2626 |
NCOR2,GCLM,NQO1,SNN,RBM4,ABHD14A,BCAP31,RGS1,LMNA,CREM,MAN1A1,CALM2,CAPN2,ABL2,RPN1,APLP2,VASP,DNAJC8,EIF4A3,ZNF200,RPN2,TP53BP2,TECR,ATP6V0D1,PPIF,TIMP2,ELL2,BTG2,MAP4K4,EZR,RPS24,EMP3,KLF6,SH3BP5,PAF1,TPD52L2,SERTAD2,UAP1,ERGIC3,RBMS1,YWHAZ,ASNA1,PRPF4,CLN3,SMURF1,PTOV1 |
| 9.049e-04 | -7.01 | GSE13485_DAY1_VS_DAY21_YF17D_VACCINE_PBMC_DN | MSigDB lists | GSE13485_DAY1_VS_DAY21_YF17D_VACCINE_PBMC_DN | 167 | 41 | 17377 | 2626 |
RECQL,ZCCHC9,GNPNAT1,GMFG,NDUFB6,SCOC,SUMO2,SLC25A12,CREBL2,IKBIP,COMMD8,MAT2B,LIN9,MRPL50,NDUFA2,MRPL34,RPF2,OSTF1,CEP63,ZNF189,UBE2QL1,TMEM126B,METTL5,RPL38,MRPS14,CLNS1A,PRIM1,RAD51C,HSPB11,CHCHD1,MRPL27,FAM3C,PPA2,RPLP1,MDH1,SNRPG,CHEK2,ACADM,TSPAN5,POT1,SNX14 |
| 9.084e-04 | -7.00 | GO_ENDOPLASMIC_RETICULUM_GOLGI_INTERMEDIATE_COMPARTMENT | MSigDB lists | GO_ENDOPLASMIC_RETICULUM_GOLGI_INTERMEDIATE_COMPARTMENT | 97 | 27 | 17377 | 2626 |
TMED7,GNPNAT1,GORASP1,SCYL1,TMED3,MCFD2,STK17B,BCAP31,MAN1A1,YIF1A,CD59,PTPN2,NUCB1,SEC23IP,GOLGA2,SURF4,TMED10,VMP1,ERGIC3,MYO18A,PIEZO1,SLC35C2,LMAN1,PDIA6,CSNK1D,TMED2,KDELR1 |
| 9.084e-04 | -7.00 | GO_ACETYLTRANSFERASE_ACTIVITY | MSigDB lists | GO_ACETYLTRANSFERASE_ACTIVITY | 97 | 27 | 17377 | 2626 |
NAT14,NAT9,GNPNAT1,KAT2A,KAT7,ELP4,EDF1,TAF6L,USP22,WDR5,SUPT7L,SAP130,CRAT,LPCAT4,OGT,NAA50,ACAT1,TAF5L,TAF12,NCOA1,NAA20,ATF2,SMARCE1,LPCAT1,SAT2,NAA60,NCOA2 |
| 9.095e-04 | -7.00 | seminoma | COSMIC cancer mutations | seminoma | 710 | 136 | 17385 | 2587 |
NF1,TMEM41B,ABCC10,CSNK2A1,MAPK14,EEF2K,CDK5,ABL2,NEK6,ATG3,PIK3R2,HADHB,SRPK2,USP34,PLK1,PLK3,NRAS,AKT2,VHL,PBK,LRBA,TLK1,AURKB,STK17B,MAP3K4,LIMK1,SOCS4,STK11,RNASEL,CHEK2,PTOV1,LIME1,MUT,DHPS,PRKAA1,TRIO,CDK13,ADCK5,EIF2AK4,PDXDC1,SRRT,JMY,MED10,DAPK1,ATP6V0A2,PHKG2,PABPC1,CSNK1G3,ABCC1,CIC,MAP4K3,EIF2AK1,KRAS,UHRF1BP1,PTTG1IP,MAP2K2,SLTM,MTR,DAPK3,MASTL,MBIP,RBM25,SNAP23,TCOF1,MYO9A,MAP3K5,CDK2,UNC13C,NRBP1,CDKN2A,CHMP2A,TP53RK,CHERP,TRIP10,RAF1,RPS6KA1,URB2,EIF3D,SMARCA4,PRKACA,LYN,TWF2,APP,CHD1,COMMD8,FLAD1,HNRNPA2B1,PRKD3,PDK2,SP100,CCDC50,ATP2A2,CDK12,SCYL3,ADCY7,CCT2,BRD4,MAP4K4,PKMYT1,TRIM28,RHBDF2,JAK1,CLK3,FASTK,HIPK2,STK38,MAPK1,SMAD4,PRPF4B,R3HCC1L,SCYL1,ATG2B,CSNK1A1,SCYL2,FOXO3,FGFR3,PTEN,PTPN11,H2AFY,MYO5A,CAMK2G,SPTAN1,GINS1,PDPK1,CSNK1G2,ASPM,NEK7,HAGH,MARK2,MAPK3,NEIL3,MAPK6,WDR91,RPS6KC1,HRAS,HIPK3 |
| 9.127e-04 | -7.00 | ATG5 (autophagy related 5) | protein interactions | 9474 | 36 | 14 | 17029 | 2761 |
CAPN2,KEAP1,TAB2,RB1CC1,ATG3,EXOC4,TKT,WIPI2,BCL2L1,IKBIP,MAP1LC3B,CAPN1,FADD,OPTN |
| 9.127e-04 | -7.00 | CREM (cAMP responsive element modulator) | protein interactions | 1390 | 36 | 14 | 17029 | 2761 |
SP100,RAD18,MIA2,ATXN1,EMP3,CSNK2A1,RBPJ,CREB1,UBE2I,CSNK1A1,PRKACA,CAMK2G,MAPK3,CREM |
| 9.127e-04 | -7.00 | S100A16 (S100 calcium binding protein A16) | protein interactions | 140576 | 36 | 14 | 17029 | 2761 |
HNRNPA2B1,SGSH,SUCLG1,TMED10,UCHL5,IDH3A,UBXN1,TOR1AIP1,SUCLG2,TCOF1,MCPH1,STMN1,APP,TMEM9 |
| 9.138e-04 | -7.00 | DAIRKEE_CANCER_PRONE_RESPONSE_BPA | MSigDB lists | DAIRKEE_CANCER_PRONE_RESPONSE_BPA | 51 | 17 | 17377 | 2626 |
TRIP12,UCK2,MOGS,GTF3A,SDHA,FAM8A1,DHX15,TSC1,RB1,FARSA,EIF2S2,PSMD1,BRWD1,GOT2,PTEN,PPM1G,FKBP5 |
| 9.138e-04 | -7.00 | NATSUME_RESPONSE_TO_INTERFERON_BETA_DN | MSigDB lists | NATSUME_RESPONSE_TO_INTERFERON_BETA_DN | 51 | 17 | 17377 | 2626 |
NCOR2,FTL,RPS2,TXN,SEC61B,COX4I1,AGFG1,PRDX1,XRCC5,PPP2CA,HINT1,SHC1,PIN1,MAPK6,E2F1,RPLP1,CAPN1 |
| 9.138e-04 | -7.00 | GO_CELL_DIVISION_SITE | MSigDB lists | GO_CELL_DIVISION_SITE | 51 | 17 | 17377 | 2626 |
RHOA,RHOC,TUBGCP5,MYH9,RACGAP1,SEPT7,ANLN,MEN1,RAB11A,TUBGCP2,RHOB,MASTL,PDXP,RAB21,CEP55,ITGB1,NDE1 |
| 9.138e-04 | -7.00 | GO_NEGATIVE_REGULATION_OF_AUTOPHAGY | MSigDB lists | GO_NEGATIVE_REGULATION_OF_AUTOPHAGY | 51 | 17 | 17377 | 2626 |
UBQLN4,FEZ2,KDM4A,PHF23,DAP,SIRT2,BCL2L1,TSC1,CHMP4A,GOLGA2,TAB2,TBC1D14,CHMP4B,BCL2,CLN3,SNRNP70,RNF5 |
| 9.141e-04 | -7.00 | ORF45 (virion phosphoprotein) | protein interactions | 4961474 | 18 | 9 | 17029 | 2761 |
AMPD2,USP7,FOXK1,SIAH1,RPS6KA1,SIAH2,MAPK1,DNMT1,MAPK3 |
| 9.141e-04 | -7.00 | NHSL2 (NHS like 2) | protein interactions | 340527 | 18 | 9 | 17029 | 2761 |
WASF2,CYFIP1,STRIP1,STRN4,SIKE1,NCKAP1,CYFIP2,ABI1,FGFR1OP2 |
| 9.141e-04 | -7.00 | Cnot2 (CCR4-NOT transcription complex, subunit 2) | protein interactions | 72068 | 18 | 9 | 17029 | 2761 |
CNOT9,XIAP,CDCA3,CNOT6,CNOT6L,MACF1,CNOT11,CNOT3,DDB1 |
| 9.141e-04 | -7.00 | DUSP5 (dual specificity phosphatase 5) | protein interactions | 1847 | 18 | 9 | 17029 | 2761 |
RPS15,RPL32,TEX10,MAPK1,AP3S1,FTSJ3,COIL,MAPK3,RPL36 |
| 9.141e-04 | -7.00 | STAT4 (signal transducer and activator of transcription 4) | protein interactions | 6775 | 18 | 9 | 17029 | 2761 |
STAT1,TKT,PIAS2,ADRB2,IL12RB1,STAT3,MAPK14,TRIM28,PDLIM2 |
| 9.141e-04 | -7.00 | ITGB1BP1 (integrin subunit beta 1 binding protein 1) | protein interactions | 9270 | 18 | 9 | 17029 | 2761 |
TANK,CCM2,ITGB1,PGRMC1,SMURF1,APP,LRP8,FAF1,KRIT1 |
| 9.150e-04 | -7.00 | Q_MOTIF | prosite domains | PS51195 | 37 | 13 | 12060 | 1670 |
DDX28,DDX56,DDX47,DDX24,EIF4A3,DDX20,DDX5,DDX31,DDX39A,DDX52,DDX42,DDX17,DDX23 |
| 9.174e-04 | -6.99 | cellular response to ionizing radiation | biological process | GO:0071479 | 64 | 20 | 17256 | 2622 |
TGFB1,NET1,RAD51AP1,TMEM109,BCL2L1,ELK1,BLM,MAPK14,RHOB,XRCC5,MDM2,INTS7,TANK,DNM2,H2AFX,CHEK2,SPIDR,HRAS,EEF1D,IFI16 |
| 9.178e-04 | -6.99 | EIF2S1 (eukaryotic translation initiation factor 2 subunit alpha) | protein interactions | 1965 | 82 | 25 | 17029 | 2761 |
CYLD,EWSR1,POLR2G,CASP6,RPL15,CSNK2A1,EIF2AK1,BRCA1,RPL27A,EIF1B,SDHA,CDC73,RPA1,CAND1,PTPN2,RPA2,RPN1,UPF1,EIF2S2,HUWE1,QARS,MAP4,YBX1,EIF5,CDC37 |
| 9.178e-04 | -6.99 | GADD45A (growth arrest and DNA damage inducible alpha) | protein interactions | 1647 | 82 | 25 | 17029 | 2761 |
FTL,RPS2,DCTN2,GADD45G,CCNB1,MAPK14,CDK11A,GNB2,SH3GLB1,FAS,MAP3K4,MDM2,PCNA,CHD3,ZHX1,QARS,GADD45B,FAM83D,KHSRP,RBPJ,MAPK1,STAT3,DNMT1,NRBP1,PTPRK |
| 9.178e-04 | -6.99 | VAMP2 (vesicle associated membrane protein 2) | protein interactions | 6844 | 82 | 25 | 17029 | 2761 |
USP7,EXOC3,TDP1,DNAJC5,SEPT9,UBXN1,ILF3,TMEM216,LAMTOR3,FLOT1,ATP6V0A1,FKBP2,BCAP31,LMNA,CALM2,PRKD3,HGS,TMED10,HUWE1,SNAP29,SNAP23,PRDX5,ASNA1,UBE2M,TIMM50 |
| 9.205e-04 | -6.99 | CDK2AP1 (cyclin dependent kinase 2 associated protein 1) | protein interactions | 8099 | 52 | 18 | 17029 | 2761 |
RPS15,MTA2,CDK2AP2,TMEM165,MBD3,HMG20A,SH3GLB1,ZNF420,CHD3,MBD2,MTA1,PHF14,COPS7B,MRFAP1L1,RBBP4,CDK2,STRAP,HDAC2 |
| 9.205e-04 | -6.99 | RIPK2 (receptor interacting serine/threonine kinase 2) | protein interactions | 8767 | 52 | 18 | 17029 | 2761 |
FGFR1OP,BIRC3,PHB2,XIAP,RPL38,UBE2I,PRMT2,KDM3A,BIRC2,CFLAR,MAP3K4,IRF4,TAB2,RPS14,MAVS,TRAF5,SMURF1,SMAD4 |
| 9.210e-04 | -6.99 | MRPL38 (mitochondrial ribosomal protein L38) | protein interactions | 64978 | 100 | 29 | 17029 | 2761 |
KDM3B,MRPL9,MRPL42,MRPL39,MRPL12,RPL6,ILF3,FLOT1,CSNK2A1,MRPL16,OGDH,ANLN,ARMC8,HAUS2,MRPL19,PRIM1,MRPL50,MID1IP1,MTMR4,MPV17,DUSP11,MRPL40,MRPL21,MRPL11,MRPL13,MRPL3,MRPL32,MRPL57,FUBP1 |
| 9.210e-04 | -6.99 | AHNAK (AHNAK nucleoprotein) | protein interactions | 79026 | 100 | 29 | 17029 | 2761 |
CYLD,HNRNPAB,SUMO2,EZR,MYH9,GORASP2,GALK2,PPP3CB,BRCA1,PLEC,CAPZA2,MCM2,SEC16A,STMN1,TARS,ISG15,RPA1,RPA2,AHNAK,CDC42,TARDBP,CDK2,XRCC4,HNRNPDL,ATF2,POT1,CDKN2A,EEF1D,CDC5L |
| 9.286e-04 | -6.98 | autophagosome | cellular component | GO:0005776 | 94 | 26 | 18223 | 2701 |
FTL,TBC1D12,UBQLN4,ATG9A,RAB7A,VTI1A,RAB23,PIP4K2C,WDR81,UBQLN2,MAP1LC3B,BECN1,PIP4K2A,SH3GLB1,PLEKHF2,OPTN,TBC1D17,RALB,VMP1,RAB24,SNAP29,TBC1D14,RPN2,TICAM1,WIPI2,CLN3 |
| 9.298e-04 | -6.98 | GSE45382_UNTREATED_VS_TGFB_TREATED_MACROPHAGES_UP | MSigDB lists | GSE45382_UNTREATED_VS_TGFB_TREATED_MACROPHAGES_UP | 188 | 45 | 17377 | 2626 |
HIVEP3,UBE2E2,MIF4GD,FEZ2,GNPDA1,DAP,CHD1L,GSPT2,VPS45,DCUN1D4,FERMT3,VAV1,PA2G4,H2AFY,AHCY,DNMT1,ADCY7,PRPF19,ERCC1,ARHGAP17,MAPRE2,MIOS,SEPT9,DENND4C,ZNF202,EMB,KIAA0930,ATP6V0A1,ARHGAP15,PLEKHF2,SLC19A1,ATP1A1,ITPRIPL1,CCDC86,CCDC14,CDCA7L,FAM126A,MBOAT1,CHEK2,PDXK,RRS1,SMAD1,PLOD3,CHPT1,CD81 |
| 9.298e-04 | -6.98 | GSE3039_CD4_TCELL_VS_ALPHABETA_CD8_TCELL_DN | MSigDB lists | GSE3039_CD4_TCELL_VS_ALPHABETA_CD8_TCELL_DN | 188 | 45 | 17377 | 2626 |
TOMM20,NOP2,PIGQ,MDH2,SDF2L1,PLXNA1,POMP,TFRC,IRF4,ASAP2,GOT2,DPYSL2,ATIC,TAGLN2,PTGES3,CYC1,TMBIM1,METTL1,ELOVL5,FTL,SEC61B,RPRD1A,SIGMAR1,RAB7A,PCGF6,TBRG4,MTX1,NDUFA7,RPL27A,MAK16,CLNS1A,USP36,AKAP1,SLC19A1,COX5A,AEN,PRPF4,GAS2,SMPD4,RPS26,ZMAT3,SLC25A39,DDB1,GCSH,ADAM23 |
| 9.298e-04 | -6.98 | GSE6674_ANTI_IGM_VS_CPG_STIM_BCELL_DN | MSigDB lists | GSE6674_ANTI_IGM_VS_CPG_STIM_BCELL_DN | 188 | 45 | 17377 | 2626 |
SRM,CTU2,NOP2,HMGXB3,GADD45G,ARID5A,LAMTOR3,AGPAT3,BCL2L1,QSOX2,CMTM6,RGS1,KRR1,FKBP1A,KRI1,IRF4,UTP18,EXOSC1,NOC2L,RPF2,GEMIN4,POLR1B,F2R,LYPLA2,PPAN,LARS,HEMK1,SEPT9,FAM118B,UTP15,PCGF6,TBRG4,USP10,MAK16,MAT2A,BBS12,HSPA4,CCDC86,NIP7,AEN,RRS1,ZBTB11,LRP8,BYSL,SLC25A33 |
| 9.298e-04 | -6.98 | GSE17721_LPS_VS_CPG_0.5H_BMDC_UP | MSigDB lists | GSE17721_LPS_VS_CPG_0.5H_BMDC_UP | 188 | 45 | 17377 | 2626 |
PRKAB1,FAM207A,ZNF768,HLA-E,WDTC1,TKT,SMC6,METTL3,PNO1,UBXN2A,IARS,NDUFB4,TBC1D14,TANK,ADCY9,CS,COPS7B,ABCD1,ANKRD13C,MAML1,RNF26,TOP1MT,SLC35A1,ERF,SNRPB,LRBA,RNF25,SLC26A6,UHRF1BP1,MTX1,NCDN,RPA1,PTPRF,TSC1,HHEX,PQBP1,KPNA2,WDR62,ZNF598,SLC25A39,MYL12B,PARD3,GPATCH4,ADNP2,TMEM131 |
| 9.298e-04 | -6.98 | GSE32128_INOS_DEPENDENT_VS_INOS_INDEPENDENT_ACTIVATED_TCELL_DN | MSigDB lists | GSE32128_INOS_DEPENDENT_VS_INOS_INDEPENDENT_ACTIVATED_TCELL_DN | 188 | 45 | 17377 | 2626 |
FAM208B,RAB11B,SLC41A1,AP3M2,PTP4A3,SUMF1,MYO9B,RGS2,SLC20A1,LYN,TCF19,ANKIB1,FANCI,FBXO22,RALB,PHTF1,PPP6C,SRI,EI24,ANKRD13C,RPL19,CNOT6L,F2R,LPCAT1,NCOA2,PDPK1,UBQLN4,HELB,PPP1R21,OXR1,RRM2,C9orf40,RPS9,GIGYF1,MFN2,HAUS8,PON2,FBXO21,CEP55,SSNA1,KPNA2,RUFY3,XRCC4,NRBP1,MYL12B |
| 9.298e-04 | -6.98 | GSE13484_UNSTIM_VS_12H_YF17D_VACCINE_STIM_PBMC_DN | MSigDB lists | GSE13484_UNSTIM_VS_12H_YF17D_VACCINE_STIM_PBMC_DN | 188 | 45 | 17377 | 2626 |
WSB2,ZNF207,MRPL42,NF1,KLHL21,LAMTOR3,PLAGL2,C2orf49,GLRX3,PPP1R16B,APH1B,PDXDC1,MXD1,ZNF696,FASTKD3,RAB21,C1GALT1,CLUAP1,PSMD1,CGGBP1,TRIM14,TMX1,SP3,TRAFD1,ACP2,LAP3,COQ10B,SNRPB,LDHA,PSMB7,RABIF,TTC33,ARF4,PSMC4,PI4K2A,PDCD6,KIF18A,ETS2,TIMM17A,ADAM9,PITPNA,ZNF45,PDCD4,RAD51D,NXT2 |
| 9.302e-04 | -6.98 | CNOT1 (CCR4-NOT transcription complex subunit 1) | protein interactions | 23019 | 91 | 27 | 17029 | 2761 |
GPBP1L1,BTG2,AGO2,KRAS,BRCA1,CNTROB,SND1,USP22,CAPZA2,CNOT11,REEP5,ABCF1,CNOT3,PI4K2A,CNOT9,UBTF,MEX3C,CENPJ,GADD45B,CAPZA1,CNOT6,CNOT6L,EYA2,TOB1,PPP6R1,IFI16,CDC5L |
| 9.368e-04 | -6.97 | APC/C:Cdc20 mediated degradation of Securin | REACTOME pathways | R-HSA-174154 | 68 | 22 | 10287 | 1696 |
PSMA8,PTTG1,PSMB7,PSMA1,ANAPC2,CDC23,PSMD9,PSMB9,PSMB3,PSMC4,PSMD2,PSMA6,CDC16,PSMD1,CDC27,RPS27A,PSMD8,PSMD3,ANAPC7,UBE2C,PSMC1,ANAPC4 |
| 9.408e-04 | -6.97 | ER to Golgi transport vesicle membrane | cellular component | GO:0012507 | 61 | 19 | 18223 | 2701 |
TMED7,USO1,HLA-E,VTI1A,MCFD2,PEF1,SEC16A,HLA-A,CD59,SEC31A,HLA-B,PDCD6,SEC23IP,SAR1A,SCAP,TMED10,SEC24C,LMAN1,TMED2 |
| 9.408e-04 | -6.97 | histone deacetylase complex | cellular component | GO:0000118 | 61 | 19 | 18223 | 2701 |
NCOR2,TRERF1,MTA2,CSNK2A1,TAF6L,MBD3,APPL1,BRMS1,SAP130,HINT1,CHD3,HDAC7,MBD2,APPL2,RBBP4,SINHCAF,SAP30L,HDAC2,SAP30 |
| 9.420e-04 | -6.97 | GO_IMMUNE_RESPONSE_REGULATING_CELL_SURFACE_RECEPTOR_SIGNALING_PATHWAY | MSigDB lists | GO_IMMUNE_RESPONSE_REGULATING_CELL_SURFACE_RECEPTOR_SIGNALING_PATHWAY | 279 | 62 | 17377 | 2626 |
WASF2,LIME1,RAF1,ACTR3,VAV2,RAC1,CUL1,BTN3A1,PPP3CB,NCKAP1,PRKACA,PSEN1,PSMD9,LYN,CALM2,VAV1,PSMD2,NFATC3,PSMD1,PSMA6,SHC1,CDC42,PTEN,ARPC5,PIK3R2,BCL2,ABI1,PDPK1,CYFIP1,PPP3CA,NRAS,PSMA8,NCK1,DENND1B,PSMB7,PSMA1,WIPF1,KRAS,NFATC2,UBE2V1,ICAM2,CYFIP2,ARPC1A,PSMB9,PSMB3,MAPK3,PSMC4,STOML2,WAS,CSK,ELMO1,RPS27A,TAB2,PSMD8,LIMK1,PSMD3,PPP3R1,STK11,ACTB,MAPK1,PSMC1,HRAS |
| 9.426e-04 | -6.97 | stem cell population maintenance | biological process | GO:0019827 | 131 | 34 | 17256 | 2622 |
POLR2K,RAF1,NOTCH2,FOXO3,METTL3,SRRT,CDC73,TUT4,SMC3,MED10,METTL14,PELO,CTR9,MCPH1,STAT3,POLR2I,POLR2L,POLR2G,KLF10,ASPM,LDB1,POLR2D,LRP5,RTF1,ARID1A,SOX4,POLR2A,PAF1,EIF4ENIF1,PCM1,SMAD2,POLR2J,RBPJ,SMAD4 |
| 9.427e-04 | -6.97 | RABAC1 (Rab acceptor 1) | protein interactions | 10567 | 69 | 22 | 17029 | 2761 |
NAT14,PLK1,RHOA,COQ8A,WDYHV1,RAB7A,SNX15,ZFYVE21,RAB6A,RAB1A,RGS2,RAB5B,REEP5,RAB22A,RHEB,LMNA,PLEKHF2,RAP1A,RAB4A,TRIM32,WIPI2,HRAS |
| 9.427e-04 | -6.97 | PTGIR (prostaglandin I2 receptor) | protein interactions | 5739 | 69 | 22 | 17029 | 2761 |
SLC12A7,PIGN,MTX3,ATG9A,DNAAF5,ATP6V0A1,SLC4A2,SLC29A1,SLC12A9,ARL5B,RAB11A,FAM8A1,PDXDC1,TUBGCP2,XPR1,TMEM179B,GNAS,OSBPL8,PKD2,NR2F2,SLC12A2,SNX14 |
| 9.427e-04 | -6.97 | THAP1 (THAP domain containing 1) | protein interactions | 55145 | 69 | 22 | 17029 | 2761 |
ZCCHC10,POLR2L,WDYHV1,DCAF8,PRKAA1,C1orf35,CSNK2A1,PAWR,APP,TRIM26,SERF2,STRBP,PPIG,OGT,AP2B1,NUP62,MRPL11,TRAF5,NKAPD1,DVL2,BYSL,CDC5L |
| 9.436e-04 | -6.97 | PMEL (premelanosome protein) | protein interactions | 6490 | 48 | 17 | 17029 | 2761 |
ABCA3,PIGQ,TYW1,SLC26A6,SPDL1,AP3S1,CMTM6,MAD2L2,RDH11,INTS7,SLC26A2,DNAJC30,RBM15,TPCN1,SNX14,ZNF146,MFSD12 |
| 9.436e-04 | -6.97 | Tnpo1 (transportin 1) | protein interactions | 238799 | 48 | 17 | 17029 | 2761 |
SEC61B,IVNS1ABP,ZNF768,CHCHD6,RTKN,ATP1A1,SLC38A5,GRK2,KLF16,DNM2,HADHB,MRPS27,MRPL11,TOP1MT,SGF29,PDF,ESYT2 |
| 9.438e-04 | -6.97 | GO_RECOMBINATIONAL_REPAIR | MSigDB lists | GO_RECOMBINATIONAL_REPAIR | 69 | 21 | 17377 | 2626 |
RECQL,RAD51AP1,SMC6,BRCA1,BLM,GINS4,WDR48,RAD54B,RPA1,RPA2,RAD51C,PALB2,TONSL,NSMCE2,XRCC2,H2AFX,XRCC3,YY1,GEN1,RAD51D,POLQ |
| 9.438e-04 | -6.97 | KEGG_PANCREATIC_CANCER | MSigDB lists | KEGG_PANCREATIC_CANCER | 69 | 21 | 17377 | 2626 |
TGFB1,AKT2,RAF1,RAC1,E2F3,KRAS,BCL2L1,MAPK3,RB1,SMAD2,CDC42,JAK1,RALB,PIK3R2,STAT1,E2F1,STAT3,MAPK1,E2F2,SMAD4,CDKN2A |
| 9.438e-04 | -6.97 | MODULE_568 | MSigDB lists | MODULE_568 | 69 | 21 | 17377 | 2626 |
B3GALT6,BCL2L12,CHMP2A,RPLP2,ADAM10,TMX4,ACSL3,PARP4,MTMR6,ASAH1,UBE2V1,GYG1,MPG,ATP6V1B2,ATP1A1,FBXO7,METTL9,RNF14,HEXA,ABI1,RYBP |
| 9.442e-04 | -6.97 | MITOCARRIER | prints domains | PR00926 | 27 | 9 | 4652 | 473 |
SLC25A12,SLC25A19,SLC25A22,SLC25A44,SLC25A5,SLC25A43,SLC25A39,SLC25A36,SLC25A1 |
| 9.443e-04 | -6.97 | AKTIP (AKT interacting protein) | protein interactions | 64400 | 40 | 15 | 17029 | 2761 |
PDPK1,POLA2,TRIM41,TSC1,IMMT,IARS,PGGT1B,PRKDC,TWNK,TRIM32,TERF1,TIMM50,TERF2,RPA1,DCTN1 |
| 9.443e-04 | -6.97 | NAE1 (NEDD8 activating enzyme E1 subunit 1) | protein interactions | 8883 | 40 | 15 | 17029 | 2761 |
CAPN2,UBQLN4,TRIP12,PPP1R2,ATIC,UBA5,TUFM,NSFL1C,KRAS,PCYT2,TP53BP2,TATDN1,UBE2M,APP,MCTS1 |
| 9.443e-04 | -6.97 | ZNF207 (zinc finger protein 207) | protein interactions | 7756 | 40 | 15 | 17029 | 2761 |
SRSF11,ZNF207,USP7,PA2G4,HSPH1,EWSR1,RNPS1,CS,ANXA5,GPI,SND1,POLR1B,MAP2K2,SF3A2,HNRNPM |
| 9.443e-04 | -6.97 | RNASEH2B (ribonuclease H2 subunit B) | protein interactions | 79621 | 40 | 15 | 17029 | 2761 |
CLPTM1,MKNK1,NRAS,RNASEH2C,FOXM1,ARPC5,RABGAP1L,AP1M1,RRM1,ANP32E,RNASEH2A,DNAJB1,UBQLN2,HERPUD2,PDF |
| 9.443e-04 | -6.97 | GPX4 (glutathione peroxidase 4) | protein interactions | 2879 | 40 | 15 | 17029 | 2761 |
OTUD5,FKBP1A,PPIF,HINT1,PIN1,DUT,TKT,VDAC2,AKR1B1,EZR,TAGLN2,NUTF2,FKBP2,VDAC1,IMPA2 |
| 9.443e-04 | -6.97 | LDHD (lactate dehydrogenase D) | protein interactions | 197257 | 40 | 15 | 17029 | 2761 |
RPAP3,SUGP1,MAGT1,FBXO28,CGAS,ZKSCAN1,CUL3,RACGAP1,MAP7D1,ACAD8,RPL22L1,MARK2,ZC3HAV1,SMNDC1,CAND1 |
| 9.443e-04 | -6.97 | HIST1H2AG (histone cluster 1 H2A family member g) | protein interactions | 8969 | 40 | 15 | 17029 | 2761 |
NAP1L1,RPS2,RAB11B,MCM5,E2F4,RBM34,E2F1,SDC2,CUL1,SNRNP70,MCM2,PCGF1,TFG,HMGN2,CAND1 |
| 9.480e-04 | -6.96 | TGTTTAC,MIR-30A-5P,MIR-30C,MIR-30D,MIR-30B,MIR-30E-5P | MSigDB lists | TGTTTAC,MIR-30A-5P,MIR-30C,MIR-30D,MIR-30B,MIR-30E-5P | 549 | 110 | 17377 | 2626 |
KCTD7,IER2,DNMT3A,UBN1,PLAGL2,YTHDF3,PLXNA1,USP48,UBE2I,BECN1,LCLAT1,ELMOD2,EDC3,ARL6IP6,PAPOLA,CRKL,DLG5,RAB8A,ATP2A2,WDR44,DPYSL2,PIK3R2,ZCCHC2,RAD23B,JOSD1,SCYL3,ARID4A,SEH1L,SAP30,KLF10,TAOK1,E2F3,WIPF1,ATXN1,MIER2,GALNT7,SOX4,CHMP2B,ZFAND5,CBFB,EML4,FKBP3,ARF4,MAT2A,EPB41,PON2,AHNAK,BRWD1,PROSER1,WDR7,ADAM9,GLCCI1,RHEBL1,NCOR2,PPP1R12A,MECP2,C16orf87,ADO,DLGAP4,TIA1,PAWR,RGS2,AP3S1,CSNK1A1,RAB11A,XPR1,CHKA,PTPN2,CCNK,IRF4,LHX8,NUS1,KLHL20,LRRC8D,ZNF746,CAPZA1,COPS7B,CLDND1,UBE3C,MAML1,GNAI2,SGCB,TMED2,NAGPA,VOPP1,YTHDC1,ELOVL5,ELL2,ERLIN1,MAN1B1,MYBL2,KRAS,SEPT7,KDM3A,MATR3,PICALM,RHOB,PHF6,GOLGA4,GALNT2,SLC38A7,SETD3,CSNK1G1,PPP3R1,CNOT6,YWHAZ,RGL1,MAP3K5,BTBD10,CPEB2 |
| 9.530e-04 | -6.96 | TNRC6A (trinucleotide repeat containing 6A) | protein interactions | 27327 | 44 | 16 | 17029 | 2761 |
CNOT9,CENPJ,ODF2,AGO2,CUL3,GTSE1,CNOT6,BRCA1,CNTROB,CLTB,CNOT6L,EYA2,PABPC1,PICALM,TRIM65,CNOT3 |
| 9.530e-04 | -6.96 | IRF1 (interferon regulatory factor 1) | protein interactions | 3659 | 44 | 16 | 17029 | 2761 |
CTDP1,SUB1,MDM2,KEAP1,KAT2A,BIRC3,QARS,DRAP1,STAT1,POLR2D,CDKN1B,SMARCA4,CSNK2A1,YBX1,TRIM28,GTF2F1 |
| 9.530e-04 | -6.96 | MRPS10 (mitochondrial ribosomal protein S10) | protein interactions | 55173 | 44 | 16 | 17029 | 2761 |
NOL12,RPS2,MRPS15,TUFM,ILF3,MRPS14,RPL11,RXRB,RPL23A,SDHB,DAP3,MRPS27,DUSP11,TRMT10B,SNRNP70,ZC3H3 |
| 9.530e-04 | -6.96 | Kcnk1 (potassium channel, subfamily K, member 1) | protein interactions | 16525 | 44 | 16 | 17029 | 2761 |
TRAPPC13,SEC61B,DDX20,ATP5F1B,VKORC1,KTN1,TFRC,PON2,SURF4,SLC38A5,SEC61A1,NCLN,ATP5F1A,TMEM131,ABCC1,ESYT2 |
| 9.535e-04 | -6.96 | AGCACTT,MIR-93,MIR-302A,MIR-302B,MIR-302C,MIR-302D,MIR-372,MIR-373,MIR-520E,MIR-520A,MIR-526B,MIR-520B,MIR-520C,MIR-520D | MSigDB lists | AGCACTT,MIR-93,MIR-302A,MIR-302B,MIR-302C,MIR-302D,MIR-372,MIR-373,MIR-520E,MIR-520A,MIR-526B,MIR-520B,MIR-520C,MIR-520D | 323 | 70 | 17377 | 2626 |
RPS6KA1,ALKBH5,PLAGL2,KLHL18,YTHDF3,PLXNA1,DAZAP2,APP,PAPOLA,ZKSCAN1,JAZF1,RAD23B,PPP6C,JOSD1,ANKRD13C,TARDBP,TIPARP,SENP1,ZNF800,ARID4A,RAB7A,ATXN1,MCL1,RAB22A,GIGYF1,ASF1B,SUGP1,SMAD2,RBL1,CERS6,ZNF436,ADAM9,KPNA2,SLC22A23,ZBTB11,ABCA1,POLQ,KIF3B,MECP2,RHOC,ZFP91,KLF13,RAB6A,RAB11A,TFAP4,UBE2Q2,LHX8,ITGB8,PRDM4,SS18L1,ST8SIA2,MAML1,MAP3K14,LUC7L2,DCAF6,C16orf72,RB1CC1,ZMYND11,OXR1,USP42,PHF6,MTMR3,ATAD2,OSBPL8,HNRNPH3,PPP3R1,CNOT6,YWHAZ,RGL1,PURA |
| 9.542e-04 | -6.95 | BILD_SRC_ONCOGENIC_SIGNATURE | MSigDB lists | BILD_SRC_ONCOGENIC_SIGNATURE | 60 | 19 | 17377 | 2626 |
HSPH1,ASH1L,TNFAIP3,RPLP2,TSPYL4,ABCC10,YTHDC2,EHMT1,TIA1,RRM2,SECISBP2,RPL27A,CSNK1A1,FANCL,ASAP2,ACLY,SLC12A2,ZBTB11,VPS13B |
| 9.542e-04 | -6.95 | GCM_BECN1 | MSigDB lists | GCM_BECN1 | 60 | 19 | 17377 | 2626 |
UBE2D3,PLK1,USP7,MAPRE1,NUP188,NQO2,RNPS1,BCLAF1,CHKB,ARF1,DAZAP2,BECN1,EIF4H,MAPK3,BCAT2,UPF1,TIMM17A,SRSF4,HNRNPM |
| 9.542e-04 | -6.95 | chr5p15 | MSigDB lists | chr5p15 | 60 | 19 | 17377 | 2626 |
SLC12A7,EXOC3,DAP,ANKRD33B,ANKH,NSUN2,NKD2,MTMR12,SDHA,ZFR,CCDC127,LRRC14B,FASTKD3,MED10,PLEKHG4B,FBXL7,LPCAT1,BRD9,UBE2QL1 |
| 9.547e-04 | -6.95 | GSE27786_CD8_TCELL_VS_MONO_MAC_DN | MSigDB lists | GSE27786_CD8_TCELL_VS_MONO_MAC_DN | 183 | 44 | 17377 | 2626 |
RAB14,CORO7,GXYLT1,HJURP,AGTRAP,GORASP1,POC1A,TMX3,CDK11B,AP3S1,C2orf68,USP5,TMEM179B,VASP,COQ4,ARPC5,LRRC8D,KIF14,MAML1,LDLRAD3,TNRC18,AMPD2,PHF10,TIMP2,TACC1,WBP2,CCDC34,AMDHD2,CYFIP2,API5,ANKRD46,MASTL,OPTN,GOLGA2,UEVLD,OSBPL8,GADD45B,DTX4,ADAM9,SASS6,CDK2,PGAM1,ARHGAP23,YWHAH |
| 9.547e-04 | -6.95 | GSE36078_UNTREATED_VS_AD5_INF_MOUSE_LUNG_DC_DN | MSigDB lists | GSE36078_UNTREATED_VS_AD5_INF_MOUSE_LUNG_DC_DN | 183 | 44 | 17377 | 2626 |
H2AFZ,GXYLT1,POC1A,RHOC,CHTF18,CUTA,CDCA3,C5orf30,MEF2A,SIKE1,FKBP2,MAD2L2,NUP205,C1GALT1,CCNA2,DPYSL2,DNAAF2,SEPT11,FNIP2,TMEM14C,SMC4,PTPRK,MOB4,PPIF,PPP3CA,ZDHHC18,PPP1R18,NQO2,KAT7,CKAP2L,MEF2D,IL12RB1,SMC2,AZI2,MAPK3,PRIM1,NUCB1,KIF18B,TXNDC16,STT3A,COX5A,CCNB2,BRD9,CBX4 |
| 9.547e-04 | -6.95 | GSE17721_LPS_VS_CPG_12H_BMDC_UP | MSigDB lists | GSE17721_LPS_VS_CPG_12H_BMDC_UP | 183 | 44 | 17377 | 2626 |
LZTR1,ARID5A,TPX2,PLAGL2,PXMP2,HMGN3,COX4I1,CHAC2,USP48,IL21R,BIRC2,CPNE3,PHC2,RB1,RAB21,SLC38A5,PTEN,ARF5,TPST1,TIMELESS,H2AFY,FEM1B,CDKN1B,APOOL,SEH1L,TSHZ1,BRD4,HEMK1,POLR2G,GUK1,TAOK1,ZNF574,OGFR,RAB22A,HSPA1B,KEAP1,UAP1,PML,ACTB,GALNT10,GLCCI1,PDLIM5,DCAF5,PFKP |
| 9.547e-04 | -6.95 | GSE41867_DAY15_EFFECTOR_VS_DAY30_MEMORY_CD8_TCELL_LCMV_ARMSTRONG_UP | MSigDB lists | GSE41867_DAY15_EFFECTOR_VS_DAY30_MEMORY_CD8_TCELL_LCMV_ARMSTRONG_UP | 183 | 44 | 17377 | 2626 |
DHPS,SNX15,LAMTOR3,TIA1,RRAGC,SIRT2,B4GALT4,SPR,LYRM2,ARID1B,RGS1,ABL2,MDM2,THADA,ATP13A3,FEM1B,FNIP2,TIPARP,C12orf75,SRPK2,SRSF11,ZDHHC18,LONRF3,TANC1,CCNF,CYFIP2,PTTG1IP,ZFAND5,OPTN,ABHD5,SH3BP5,NIP7,MAFK,HPS5,WDR4,DTX4,MPV17,SAMD8,RGL1,ZMIZ1,ATP6V1C1,CDK2,CABLES1,N4BP2L2 |
| 9.547e-04 | -6.95 | GSE37416_12H_VS_48H_F_TULARENSIS_LVS_NEUTROPHIL_UP | MSigDB lists | GSE37416_12H_VS_48H_F_TULARENSIS_LVS_NEUTROPHIL_UP | 183 | 44 | 17377 | 2626 |
MAPRE1,CYLD,MAX,PPP1R12A,TMX4,TOR1AIP1,YTHDC2,TIA1,MYH9,CHIC2,TOP2B,SLC35B2,C2orf49,FAM8A1,MBD4,SRXN1,CREM,RAB21,SP100,SNX18,PHTF1,MAP3K14,CNOT6L,PLCL2,CLTB,ZNF710,CNPY3,IMPA2,CDKN2AIP,TACC1,KCTD20,CBFB,OSBPL11,TAB2,L3MBTL3,GRIPAP1,STK38,CAB39,CNOT6,SMURF1,MAPK1,SMAD4,DEF6,ZSWIM6 |
| 9.547e-04 | -6.95 | GSE12845_NAIVE_VS_PRE_GC_TONSIL_BCELL_UP | MSigDB lists | GSE12845_NAIVE_VS_PRE_GC_TONSIL_BCELL_UP | 183 | 44 | 17377 | 2626 |
PPCS,DCAF15,IVNS1ABP,UBXN1,AP3M2,ZNF107,CHKB,DAZAP2,EIF1B,KIF13B,PRDM4,FBXO7,DNM2,DCP1A,FEM1B,CNPY3,SAP30L,FRMD8,CGGBP1,PDLIM2,DDX28,PPP3CA,BRD4,TLK1,RPL8,CYP20A1,WBP2,ELK1,METTL22,RPS9,MAN2A2,HLA-B,INF2,AHNAK,FASTK,FAM3C,ARAP1,RPLP1,ZNF268,DUSP11,TICAM1,MAP3K5,TMEM159,ARRB2 |
| 9.547e-04 | -6.95 | GSE18893_CTRL_VS_TNF_TREATED_TCONV_24H_UP | MSigDB lists | GSE18893_CTRL_VS_TNF_TREATED_TCONV_24H_UP | 183 | 44 | 17377 | 2626 |
PWWP2A,LUZP1,KIAA0100,MUM1,DHX9,TIA1,HMGN3,THRAP3,GLRX3,ABHD14A,RPAIN,MIS12,RABGAP1L,SEC24C,RRBP1,SLC35B4,PTPN11,GPATCH1,GPD1L,TMX1,B3GALT6,DDX28,STAU1,TACC1,KAT7,PSMA1,ASB13,API5,TTC33,SPPL2B,DHX15,NSA2,EIF3K,KIF18A,GOLGA4,CDC27,ZC3H7B,ACLY,PTAR1,CCDC59,HRAS,ATMIN,GPATCH4,ANAPC4 |
| 9.547e-04 | -6.95 | GSE39820_TGFBETA1_IL6_VS_TGFBETA1_IL6_IL23A_TREATED_CD4_TCELL_DN | MSigDB lists | GSE39820_TGFBETA1_IL6_VS_TGFBETA1_IL6_IL23A_TREATED_CD4_TCELL_DN | 183 | 44 | 17377 | 2626 |
SARNP,LYRM4,C19orf53,PLXNC1,CASP6,MRPS15,UQCR10,ALKBH5,OLA1,POMP,SNRPD3,UBE2I,MAN1A1,NDUFB4,ATG3,BANF1,TECR,MRPL21,CNPY3,ZNRD1,MRPL32,ZNF524,ELOVL5,TIMM8B,DRAP1,PSMB7,PSMG1,BOLA1,MRPL16,GLO1,NDUFA7,LY6E,MRPS14,GAR1,GINS4,PRIM1,DTWD1,TRIM47,MRPL2,NAA20,PDSS2,MZT2B,CBX4,HIGD2A |
| 9.555e-04 | -6.95 | GO_REGULATION_OF_TYPE_I_INTERFERON_PRODUCTION | MSigDB lists | GO_REGULATION_OF_TYPE_I_INTERFERON_PRODUCTION | 107 | 29 | 17377 | 2626 |
DDX58,OTUD5,CYLD,TNFAIP3,POLR2L,POLR2K,PRKDC,DHX9,FLOT1,POLR3GL,IRF3,POLR3K,IRF5,ISG15,XRCC5,RPS27A,STAT6,PIN1,NLRC5,DTX4,CRCP,HMGB2,TICAM1,TRIM32,MAVS,RNF135,ZC3HAV1,PCBP2,IFI16 |
| 9.555e-04 | -6.95 | MODULE_427 | MSigDB lists | MODULE_427 | 107 | 29 | 17377 | 2626 |
CYTH1,MIF4GD,ATXN3,ACP2,ZNF559,SNX2,GALC,ACSL3,PFKFB3,DNAJB1,CCNB1,EPHX2,MIEN1,PSEN1,CHCHD6,MAD2L2,HSPA1B,DDX17,MCTS1,HMGN2,GTPBP3,NUP210,AP1S1,SIL1,PPP1R11,ATE1,GAS2,RNF139,GEMIN7 |
| 9.615e-04 | -6.95 | cytosolic ribosome | cellular component | GO:0022626 | 119 | 31 | 18223 | 2701 |
RPL29,RPS15,RPL35,RPS2,RPLP2,RPL6,RPS10,RPL38,RPL8,RPL15,RPS24,EIF2A,EIF2AK4,RPL27A,RPS9,RPSA,MCTS1,RPL23A,RPL36,RPL11,RPL37,GEMIN5,RPL32,RPL17,RPS27A,RPS14,EIF2D,RPLP1,RPL19,RPS26,RPL22L1 |
| 9.650e-04 | -6.94 | FKBP10 (FK506 binding protein 10) | protein interactions | 60681 | 25 | 11 | 17029 | 2761 |
HSPBP1,PPME1,ACTR3,H2AFX,DNAAF5,CHCHD2,DDX5,EFL1,TTLL12,COA7,NPLOC4 |
| 9.650e-04 | -6.94 | SLK (STE20 like kinase) | protein interactions | 9748 | 25 | 11 | 17029 | 2761 |
HGS,KEAP1,PPP1R2,MAP4,ARHGEF1,RBM8A,MRPL43,NSFL1C,YWHAZ,TTC4,PITHD1 |
| 9.650e-04 | -6.94 | LSM11 (LSM11, U7 small nuclear RNA associated) | protein interactions | 134353 | 25 | 11 | 17029 | 2761 |
GEMIN5,ZNF473,SNRPB,TOP3A,DDX20,KRAS,TAF5L,SNRPG,CLNS1A,SSSCA1,GEMIN7 |
| 9.650e-04 | -6.94 | Crnkl1 (crooked neck pre-mRNA splicing factor 1) | protein interactions | 66877 | 25 | 11 | 17029 | 2761 |
GOLGA4,SNRNP200,CDC40,XAB2,PPIL2,PPIE,DHX8,AQR,ZNF830,PRPF19,CDC5L |
| 9.650e-04 | -6.94 | IDH3G (isocitrate dehydrogenase 3 (NAD(+)) gamma) | protein interactions | 3421 | 25 | 11 | 17029 | 2761 |
SUGP1,RAB8A,PPP1R12A,AHSA1,IDH3A,PQBP1,KPNA2,ADRB2,EDF1,IDH3B,SPR |
| 9.650e-04 | -6.94 | CTDSPL2 (CTD small phosphatase like 2) | protein interactions | 51496 | 25 | 11 | 17029 | 2761 |
KPNA4,JAK1,KLF16,SCYL1,MED15,PTAR1,MYBL2,NUP153,KPNA2,RANGAP1,FBXL19 |
| 9.650e-04 | -6.94 | SUPT20H (SPT20 homolog, SAGA complex component) | protein interactions | 55578 | 25 | 11 | 17029 | 2761 |
UBQLN4,KPNA1,KAT2A,ATG9A,ATXN1,USP22,TAF6L,MAPK1,MAPK14,STAT3,SGF29 |
| 9.703e-04 | -6.94 | ZnF_RBZ | smart domains | SM00547 | 20 | 9 | 9493 | 1367 |
EWSR1,TAB2,NEIL3,NUP153,ZRANB2,FUS,ZRANB1,NPLOC4,RYBP |
| 9.721e-04 | -6.94 | Tbc1d7 (TBC1 domain family, member 7) | protein interactions | 67046 | 9 | 6 | 17029 | 2761 |
TSC1,TSC2,ATP2A2,PTTG1,LUC7L2,MBD4 |
| 9.721e-04 | -6.94 | RN7SL1 (RNA, 7SL, cytoplasmic 1) | protein interactions | 6029 | 9 | 6 | 17029 | 2761 |
GEMIN5,GEMIN6,DDX20,GEMIN4,STRAP,GEMIN7 |
| 9.721e-04 | -6.94 | PIPOX (pipecolic acid and sarcosine oxidase) | protein interactions | 51268 | 9 | 6 | 17029 | 2761 |
ELP4,NAPG,FKBP5,PEX5,ELP5,POT1 |
| 9.737e-04 | -6.93 | Znf_RanBP2_sf | interpro domains | IPR036443 | 23 | 10 | 18492 | 2768 |
EWSR1,MDM2,TAB2,NEIL3,NUP153,ZRANB2,FUS,ZRANB1,NPLOC4,RYBP |
| 9.741e-04 | -6.93 | GTPase activity | molecular function | GO:0003924 | 291 | 65 | 17224 | 2647 |
RHOG,RAB14,RAB11B,RAC1,RRAGC,EFL1,GNB2,RAB21,RAB8A,RAP1A,CDC42,RALB,RAB35,RAB4A,DNM2,SEPT11,EIF5,NRAS,RHOBTB3,SEPT9,RAB7A,ARHGDIB,RAB1A,RAB5B,LSG1,RAB22A,RAB2B,RHEB,ARF4,SEPT1,RAB24,TUBB,RHEBL1,MUT,RHOC,GSPT2,RAB23,ARF1,RAB6A,IFT27,GFM2,RAB11A,TMEM250,GTPBP3,ARF5,EFTUD2,GNAI2,RHOA,NOA1,GTPBP4,TUFM,SEPT8,BMS1,KRAS,RIT1,RHOT1,SEPT7,RHOT2,GUF1,RHOB,MFN2,GNAS,GNA12,RAB18,HRAS |
| 9.776e-04 | -6.93 | ELM2 | smart domains | SM01189 | 13 | 7 | 9493 | 1367 |
RCOR1,MIER2,TRERF1,RCOR3,MTA2,MTA1,MIER1 |
| 9.791e-04 | -6.93 | GSE32423_MEMORY_VS_NAIVE_CD8_TCELL_IL7_DN | MSigDB lists | GSE32423_MEMORY_VS_NAIVE_CD8_TCELL_IL7_DN | 178 | 43 | 17377 | 2626 |
UNK,NUP188,GPBP1L1,TMEM41B,UCK2,TMEM97,KIF23,PABPC4,CHKA,PAPOLA,TMCC3,PPP1R3B,SLC31A1,SAR1A,RALB,PRDM4,SLC44A1,ORAI1,POLR1B,DVL2,RNF169,ALDH9A1,EBAG9,TRAPPC9,GUK1,KLF10,LAP3,MRS2,USP10,WDR82,MEF2D,API5,SYMPK,TRIM28,TMEM41A,UPF1,NEK1,BRD2,LRPPRC,NUP62,NANP,ZNF830,EHD4 |
| 9.791e-04 | -6.93 | GSE15735_CTRL_VS_HDAC_INHIBITOR_TREATED_CD4_TCELL_12H_UP | MSigDB lists | GSE15735_CTRL_VS_HDAC_INHIBITOR_TREATED_CD4_TCELL_12H_UP | 178 | 43 | 17377 | 2626 |
PPCS,SYS1,ADD1,GORASP1,KLHL21,SLC2A1,CCM2,CIB1,MCCC1,ABHD14B,ZADH2,MIEN1,KTN1,RBM4,PABPC4,C14orf119,FARSA,C1GALT1,ATIC,TBC1D14,PPME1,BDH1,PDCD2,FYTTD1,SNX25,TMEM216,FBXO9,EZR,LNX2,ESYT1,ICAM2,PRMT2,GAR1,JAK1,PQBP1,SH3GLB2,SLC16A1,ACBD4,TCOF1,OSGEPL1,RPS26,PDF,GEMIN7 |
| 9.791e-04 | -6.93 | BURTON_ADIPOGENESIS_6 | MSigDB lists | BURTON_ADIPOGENESIS_6 | 178 | 43 | 17377 | 2626 |
NDUFA5,COX5B,NDUFS1,NDUFB6,SUCLG1,UQCR10,PDAP1,MCCC1,TKT,UCK1,AGPAT3,PXMP2,REEP5,SDHA,BCAT2,CDKN2C,DECR1,TANK,CS,HADHB,NDUFB9,SLC25A1,LDHB,FAM49B,MAP4K4,TUFM,OGDH,SLC25A5,CYB5A,CAT,SDHB,CHCHD3,SLC19A1,PON2,PPP2R5A,HIPK2,IMPDH1,SCARB1,CHPT1,RTN3,ABCA1,LONP2,GCSH |
| 9.791e-04 | -6.93 | GSE17974_CTRL_VS_ACT_IL4_AND_ANTI_IL12_6H_CD4_TCELL_DN | MSigDB lists | GSE17974_CTRL_VS_ACT_IL4_AND_ANTI_IL12_6H_CD4_TCELL_DN | 178 | 43 | 17377 | 2626 |
SRM,HIVEP3,MMACHC,GCLM,PIGM,PHF23,HNRNPUL2,UCK2,CHAC2,FBXO22,ASPHD2,LYAR,IRF4,PA2G4,HOMER1,VMP1,CD3EAP,BDH1,TTC9C,TXLNA,MECR,GEMIN6,PRADC1,TTLL12,CLN6,JMJD4,POU2AF1,MLEC,HPDL,TSPAN31,ERLIN1,MRS2,CRNKL1,SCFD2,ATXN1,PSMG1,FADD,SLC19A1,KEAP1,CCDC86,BAZ1B,RRS1,PDCD2L |
| 9.813e-04 | -6.93 | GGCACTT,MIR-519E | MSigDB lists | GGCACTT,MIR-519E | 117 | 31 | 17377 | 2626 |
KIF3B,CORO7,FAM53C,ZFP91,PLAGL2,TM9SF3,RRM2,SIKE1,ARHGEF12,CADM1,BICD2,DAZAP2,KDM1B,EIF4H,RAB5B,MARK2,GIGYF1,MAT2B,C1GALT1,FBXO21,SERTAD2,PTEN,MTMR4,SPATA2,RAB35,PPA2,BAZ1B,UBE3C,NR2F2,ST8SIA2,ARID4A |
| 9.813e-04 | -6.93 | Regulation of PLK1 Activity at G2/M Transition | REACTOME pathways | R-HSA-2565942 | 90 | 27 | 10287 | 1696 |
PLK1,FGFR1OP,MAPRE1,PPP1R12A,DYNLL1,DCTN2,CUL1,HAUS4,CCNB1,BORA,PRKACA,HAUS2,OPTN,HAUS8,RAB8A,PCM1,CCP110,RPS27A,CENPJ,ODF2,SSNA1,CEP63,NDE1,CCNB2,TUBB,CSNK1D,DCTN1 |
| 9.828e-04 | -6.93 | BROWNE_HCMV_INFECTION_24HR_UP | MSigDB lists | BROWNE_HCMV_INFECTION_24HR_UP | 137 | 35 | 17377 | 2626 |
CTDP1,TRIP10,GORASP1,TMEM109,SLC29A1,SPR,METTL3,CHKA,CREM,FKBP1A,MCM5,SS18L1,TAF5L,CLTB,CAMK2G,MED22,CDC5L,CLPTM1,ABHD2,SNRPB,E2F3,RRM2,ATP6V0A1,NFATC2IP,TOMM40,PRIM1,BRMS1,KEAP1,PSMD3,PPM1G,PPP3R1,CDK2,COIL,TERF1,LRP8 |
| 9.828e-04 | -6.93 | GCM_PTK2 | MSigDB lists | GCM_PTK2 | 137 | 35 | 17377 | 2626 |
WSB2,SNX27,PKP4,TMEM184B,GORASP1,KLHL21,LANCL1,DCUN1D4,FAM8A1,ZER1,MOAP1,NAPG,PPIG,GLTP,FNIP2,CLDND1,AHCYL1,ZNF710,SAP30L,CAMK2G,CLCN3,TRIM8,ZNF84,MAP4K4,WBP2,NDRG3,FBXO21,EIF4ENIF1,GOLGA7,USP32,MEGF9,SLAIN1,PREPL,DYNC1LI2,NIPA1 |
| 9.854e-04 | -6.92 | GSE29618_MONOCYTE_VS_MDC_DN | MSigDB lists | GSE29618_MONOCYTE_VS_MDC_DN | 199 | 47 | 17377 | 2626 |
RPS2,GOLPH3L,PHB2,SLC2A1,PTTG1,TMEM109,UCK2,ENSA,PPP1R16B,BZW2,RGS1,SSR1,CD59,IRF4,SUB1,MZT2A,NUP210,EI24,BCL2,NDUFS8,RPL19,CNN2,PPA1,CCT2,PHF10,HMGN1,CDC123,NET1,DENND1B,RAB7A,GNG7,LRBA,RPSA,EIF3K,SH3BP5,PON2,HINT1,PDLIM1,TAB2,RPS27A,CCDC6,GOLGA8A,PPM1G,AEN,TMEM14A,TOB1,ZC3HAV1 |
| 9.863e-04 | -6.92 | spliceosomal tri-snRNP complex | cellular component | GO:0097526 | 31 | 12 | 18223 | 2701 |
SART1,SNRNP200,LSM6,SNRPB,EFTUD2,LSM8,PRPF4,SNRPG,PRPF3,SNRPD3,TXNL4A,PRPF18 |
| 9.883e-04 | -6.92 | CREIGHTON_ENDOCRINE_THERAPY_RESISTANCE_3 | MSigDB lists | CREIGHTON_ENDOCRINE_THERAPY_RESISTANCE_3 | 654 | 128 | 17377 | 2626 |
TMED7,GXYLT1,UQCR10,FAM129A,ENSA,TGOLN2,NANS,OAT,MAP1LC3B,SYNRG,ATPAF1,NEK6,ETV6,SLC44A1,FBXW2,NFU1,DRAM2,ERCC1,MIOS,EAF2,GALNT7,KRTCAP2,PRPSAP1,STK17B,RAB22A,SMAD2,WSB2,SCOC,CIB1,ASAH1,B4GALT4,DOCK11,TMEM165,PDXDC1,PRPF18,ATG4A,GNS,C1GALT1,SLC31A1,MED8,INPP5A,SNX18,BDH1,TPST1,ACAD8,SLC12A2,FAM171A1,FDFT1,VOPP1,GCC2,ELL2,ERLIN1,ACSL3,RDH10,CYB5A,DTWD1,CAT,GNAS,SLCO4A1,TTC13,UAP1,NSF,APPL2,PIAS2,PITPNA,PDLIM5,NIPA1,GLT8D1,PRKAB1,UGP2,CAST,RPS6KA1,KIAA0232,TM9SF3,DAZAP2,LYN,MEAF6,ATP6V0B,BRPF3,SAR1A,LPIN2,PDIA6,SCYL3,MOSPD1,ERMP1,FAM118B,NARF,RAB1A,EML4,TMEM41A,WDR7,TSPAN5,EYA2,GOLPH3L,DAP,GNE,TRAK1,CAPN2,GOLM1,ADD3,CTSS,RRBP1,TANK,H2AFY,CITED2,TPCN1,S100A6,TSHZ1,PDPK1,PHF20L1,LONRF3,PSPC1,RFFL,HEBP2,MTMR12,SMAP2,ELMO1,ZHX1,TTLL4,ACOX1,FAM3C,DBI,PITX1,PGRMC1,DTX4,LY75,RGL1,ACADM |
| 9.889e-04 | -6.92 | viral life cycle | biological process | GO:0019058 | 198 | 47 | 17256 | 2622 |
CHMP2A,NDC1,NUP188,PDCD6IP,RAE1,NUP54,ITGB5,PCBP1,XPR1,NUP205,TFRC,WWP2,NUP210,GRK2,CDC42,ZNF639,SIVA1,NUP107,NUP153,LRSAM1,NUP85,PCBP2,SEH1L,RAB7A,SELPLG,NUP155,CHMP2B,RAB1A,RPSA,NMT2,HSPA1B,SCARB2,KPNA4,IDE,KPNA1,CHMP4A,RPS27A,ITGB1,NUP62,CHMP4B,KPNA2,SCARB1,VPS4A,CD81,CHMP7,NUP58,AAAS |
| 9.891e-04 | -6.92 | WD40_repeat_CS | interpro domains | IPR019775 | 164 | 40 | 18492 | 2768 |
WSB2,CORO7,CDC40,COPA,TRAF7,RAE1,POC1A,STRN4,WDR5,GNB2,WDR48,DTL,UTP18,FBXW2,TAF5L,CORO1A,STRAP,CSTF1,WDR41,MLST8,PRPF19,WDR1,WDR18,SMU1,UTP15,WDHD1,WDR82,EML4,GEMIN5,WDR11,BRWD1,SCAP,CORO1C,TBL3,WDR59,WDR7,PRPF4,RBBP4,BRWD3,AAAS |
| 9.909e-04 | -6.92 | HIST4H4 (histone cluster 4 H4) | protein interactions | 121504 | 105 | 30 | 17029 | 2761 |
BRD4,HJURP,KAT2A,VHL,SUZ12,CUL3,WDR5,MEN1,MCM2,GNB2,ASF1B,CHAF1A,CAND1,RB1,MDM2,CTNNBL1,SIAH1,UCHL5,KMT5A,NOC2L,H2AFX,ANP32A,FUS,ORC3,H3F3A,RBBP4,PARP10,CBX4,ARID4A,NCOA2 |
| 9.910e-04 | -6.92 | GO_GOLGI_ASSOCIATED_VESICLE_MEMBRANE | MSigDB lists | GO_GOLGI_ASSOCIATED_VESICLE_MEMBRANE | 47 | 16 | 17377 | 2626 |
TMED7,COPA,GOPC,COPE,SCYL1,TMED3,SYNRG,COPG2,SPPL2B,COPB2,SPPL2A,ZDHHC13,AP1S1,CLTB,TMED2,KDELR1 |
| 9.968e-04 | -6.91 | soft_tissue-fat-liposarcoma-pleomorphic | COSMIC cancer mutations | soft_tissue-fat-liposarcoma-pleomorphic | 16 | 8 | 17385 | 2587 |
RB1,EWSR1,NRAS,NF1,PTEN,KRAS,FUS,HRAS |
| 9.968e-04 | -6.91 | central_nervous_system-brain-glioma-ependymoma_Grade_III-IV | COSMIC cancer mutations | central_nervous_system-brain-glioma-ependymoma_Grade_III-IV | 16 | 8 | 17385 | 2587 |
TSC1,RB1,NRAS,PTEN,KRAS,H3F3A,HRAS,CDKN2A |
| 9.968e-04 | -6.91 | urinary_tract-carcinoma | COSMIC cancer mutations | urinary_tract-carcinoma | 16 | 8 | 17385 | 2587 |
FGFR3,TSC1,NRAS,PTEN,STK11,KRAS,HRAS,CDKN2A |
| 9.975e-04 | -6.91 | NUP98 (nucleoporin 98) | protein interactions | 4928 | 78 | 24 | 17029 | 2761 |
USP7,UNK,RAE1,PTTG1,NUP54,CSNK2A1,KRAS,FAM136A,UBE2I,CDC73,LMNA,PAF1,NUP107,TNPO2,NUP62,CHMP4B,NUP153,MOB1A,NUP58,NUP85,IFI16,FAF1,SEH1L,CDC37 |
| 9.975e-04 | -6.91 | RPS6KB1 (ribosomal protein S6 kinase B1) | protein interactions | 6198 | 78 | 24 | 17029 | 2761 |
PDPK1,PPP1R9B,RBX1,VHL,RAC1,RRM2,CSNK2A1,LYN,PIP4K2A,APP,MXD1,EIF3H,RHEB,MAPK3,EEF2K,PPP2CA,MDM2,NEK6,CDC42,PIN1,STAT1,STK11,PPP5C,MAPK1 |
| 9.975e-04 | -6.91 | TPM4 (tropomyosin 4) | protein interactions | 7171 | 78 | 24 | 17029 | 2761 |
TELO2,MAPRE1,ADD1,DCTN2,ILF3,PSMA1,MYH9,COX4I1,CAPZA2,ANLN,MCM2,SRXN1,PSMD2,PSMD1,PSMA6,ATP1A1,CORO1C,MYO18A,COX5A,OSTF1,SNRNP70,CDK2,ATF2,SMURF1 |
| 9.975e-04 | -6.91 | ARF6 (ADP ribosylation factor 6) | protein interactions | 382 | 78 | 24 | 17029 | 2761 |
CYTH1,STAU1,DHPS,GGA1,ACAP1,EZR,KIF23,ARFIP2,TGOLN2,AP1B1,APP,PABPC4,PIP5K1C,ASAP2,GART,AP3S2,KIF13B,LRPPRC,ATP6V0C,RUVBL2,CDK2,ARRB2,ECPAS,CAPN1 |
| 9.999e-04 | -6.91 | V$ARNT_02 | MSigDB lists | V$ARNT_02 | 231 | 53 | 17377 | 2626 |
ZBTB10,RPS2,PDCD6IP,PPCS,H2AFZ,RRP15,RRAGC,GYG1,SNN,STMN1,COMMD8,GNB2,CDKN2C,PA2G4,NFATC3,SLC38A5,ARPC5,UTP18,ATG3,PRDM4,JOSD1,CEP63,MRPL40,FBXL19,ANKHD1,AATF,SNX2,C16orf72,GMFB,TOPORS,UBE4B,NDUFA7,PICALM,AKAP1,PTPRF,GNAS,SEC23IP,SYNCRIP,BRD2,SLC38A7,CSK,RAB24,HPS5,PRPS2,MRPL27,ASNA1,RGL1,RBBP4,ATP6V1C1,CLN3,HEXA,PURA,SMNDC1 |
| 1.001e-03 | -6.91 | dedifferentiated | COSMIC cancer mutations | dedifferentiated | 27 | 11 | 17385 | 2587 |
GNAS,RB1,EWSR1,NRAS,NF1,PTEN,NUP107,KRAS,FUS,HRAS,CDKN2A |
| 1.002e-03 | -6.91 | 1-acylglycerol-3-phosphate O-acyltransferase activity | molecular function | GO:0003841 | 19 | 9 | 17224 | 2647 |
AGPAT2,LPCAT4,AGPAT1,AGPAT3,MBOAT1,LCLAT1,LPCAT1,TAZ,ABHD5 |
| 1.004e-03 | -6.90 | duodenum | COSMIC cancer mutations | duodenum | 35 | 13 | 17385 | 2587 |
GNAS,CDKN2C,FGFR3,NRAS,SF3B1,MSH2,PTPN11,STK11,KRAS,MEN1,SMAD4,HRAS,CDKN2A |
| 1.007e-03 | -6.90 | CAD (carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase) | protein interactions | 790 | 119 | 33 | 17029 | 2761 |
CYLD,SUMO2,SMARCA4,SEC16A,PRKACA,PSMD2,PSMD1,SHC1,MEX3C,IARS,ZNF746,NCOA2,HTRA2,STAU1,IDH3A,VHL,CUL3,NFATC2,DNAJA1,BRCA1,MCM2,CCT8,PSMC4,PPP2CA,DERL1,EPRS,ATP1A1,SMAD2,ACTB,RUVBL2,MAPK1,CDK2,IPO4 |
| 1.008e-03 | -6.90 | PFDN4 (prefoldin subunit 4) | protein interactions | 5203 | 65 | 21 | 17029 | 2761 |
CTU2,TRAF7,MIOS,POC1A,COMMD4,GNB2,PFDN5,MTFR1L,FBXO28,SPATA2,PDRG1,CENPJ,PPM1G,MSH2,SIL1,ACTB,PRPF4,CREB1,ATF2,DCAF5,TUBB |
| 1.008e-03 | -6.90 | MAPK7 (mitogen-activated protein kinase 7) | protein interactions | 5598 | 65 | 21 | 17029 | 2761 |
PPP3CA,RAF1,C5orf30,MEF2A,MEF2D,PKM,ETS1,APP,DOT1L,PFDN5,ZBED6CL,HSPA4,PFDN4,PML,YWHAZ,ACTB,ATP5F1A,YWHAH,UBE2C,TUBB,CDC37 |
| 1.009e-03 | -6.90 | GO_DEPHOSPHORYLATION | MSigDB lists | GO_DEPHOSPHORYLATION | 258 | 58 | 17377 | 2626 |
CTDP1,PPP1R12A,EYA1,PPP1R15B,PTP4A3,CYCS,PPP3CB,EPHX2,DUSP22,EPM2A,UBLCP1,PTPN2,PPP1R3B,PDXP,PTEN,INPP5A,NT5DC1,MTMR4,IMPAD1,LPIN2,PPP4R1,PPP6C,PTPN11,BCL2,CDC25B,MINPP1,RPRD1B,HDHD2,CTDSP2,ILKAP,IMPA2,CAMK2G,TIMM50,PTPRK,NTPCR,PPP3CA,ACP2,PTPN18,RPRD1A,NCK1,MTMR6,PFKFB3,STYXL1,PTPRF,MTMR3,PPP2CA,ATP1A1,DUSP3,PPM1G,PPA2,PTPN7,PPP3R1,DUSP11,PTPDC1,PPP5C,NANP,PGAM1,EYA2 |
| 1.011e-03 | -6.90 | central_nervous_system-brain-glioma-oligodendroglioma_Grade_II | COSMIC cancer mutations | central_nervous_system-brain-glioma-oligodendroglioma_Grade_II | 75 | 22 | 17385 | 2587 |
PDCD6IP,NRAS,VHL,CIC,COPE,KRAS,SLC4A2,PLXNA1,SEC16A,MACF1,GNAS,CDKN2C,FGFR3,RB1,AHNAK,GOLGA4,PTEN,AKNA,H3F3A,HRAS,CDKN2A,FUBP1 |
| 1.012e-03 | -6.90 | CAGTATT,MIR-200B,MIR-200C,MIR-429 | MSigDB lists | CAGTATT,MIR-200B,MIR-200C,MIR-429 | 447 | 92 | 17377 | 2626 |
FEZ2,DNMT3A,ARID2,ANK3,RAC1,XIAP,YTHDF3,AGFG1,UBE2I,GIT2,PAPOLA,ANKRD28,CRKL,RAB21,ATP2A2,SIAH1,PIN1,JAZF1,PDS5B,FBXW2,NUP153,TARDBP,BCAP29,FAM76B,SPTSSA,COPS8,KLF10,FAM118B,GABPA,MBLAC2,RAB7A,MAP4K4,E2F3,WIPF1,ATXN1,ANLN,SRSF1,PPP2CA,VEZF1,BRWD1,CERS6,GOLGA8A,CORO1C,OGT,CAB39,CBX4,TUBB,SDC2,PM20D2,RLF,ETS1,FAM8A1,PDCD10,CLIC4,MEX3C,BUD31,BTF3L4,CITED2,PIKFYVE,HDHD2,NCOA2,CSNK1G3,RNF5,LYPLA2,PDPK1,PPP1R9B,RHOA,FOXK1,C16orf72,NUDT4,OXR1,RDH10,RABIF,RTF1,KRAS,MAP4K3,SYVN1,RHOT1,FXR1,MATR3,APPL1,PHF6,OSBPL11,GOLGA7,CNOT6,RGL1,PPP6R3,TOB1,NIPA1,EGLN1,S100PBP,SMARCD1 |
| 1.015e-03 | -6.89 | OGT (O-linked N-acetylglucosamine (GlcNAc) transferase) | protein interactions | 8473 | 96 | 28 | 17029 | 2761 |
USP7,UNK,CYLD,LAP3,KMT2E,TRAK1,CSNK2A1,AGFG1,BRCA1,KDM1B,HCFC1R1,ASXL2,KCMF1,CRKL,KIF5B,FARSA,TPD52L2,HSPBP1,HUWE1,PPME1,WDR4,OGT,NUP62,RBPJ,PDXK,CDK2,SMURF1,RPRD1B |
| 1.015e-03 | -6.89 | EXOSC4 (exosome component 4) | protein interactions | 54512 | 96 | 28 | 17029 | 2761 |
DDX47,EXOSC6,DHPS,IVNS1ABP,MECP2,WDR18,RPS10,PSMA1,KRAS,EXOSC9,UTP3,GAR1,COMMD4,PTPN2,PSMA6,NEK1,EXOSC7,UPF1,EIF2S2,TXNDC16,LRRC8D,EXOSC1,UPF2,SMPD4,MRPL48,LRRC59,TSEN15,IFI16 |
| 1.015e-03 | -6.89 | UPF2 (UPF2, regulator of nonsense mediated mRNA decay) | protein interactions | 26019 | 96 | 28 | 17029 | 2761 |
MIF,RPS15,TK1,EXOSC6,PHB2,TRIP10,ABCF2,RBM8A,RPL8,RNPS1,AGPAT1,LDHA,KIF15,NDUFA7,BLM,MAP1LC3B,PARN,PAIP1,CENPU,UPF1,SERF2,PITX1,EXOSC1,ITGB1,UPF2,FUS,MRPL40,SMARCD1 |
| 1.015e-03 | -6.89 | IMPDH2 (inosine monophosphate dehydrogenase 2) | protein interactions | 3615 | 96 | 28 | 17029 | 2761 |
NOP9,UBQLN4,CYLD,SNX2,VHL,INTS13,CUL3,RPL15,BRCA1,SLC25A44,MCM2,VDAC1,SEC16A,API5,PARK7,FANCI,RPA1,RPA2,HUWE1,AHSA1,CTPS1,IMPDH1,XRCC3,CHMP4B,COPS6,CDK2,ANKRD9,NMD3 |
| 1.015e-03 | -6.89 | GSE43955_TH0_VS_TGFB_IL6_TH17_ACT_CD4_TCELL_60H_UP | MSigDB lists | GSE43955_TH0_VS_TGFB_IL6_TH17_ACT_CD4_TCELL_60H_UP | 194 | 46 | 17377 | 2626 |
ZBED3,HIVEP3,WASF2,IER2,DNMT3A,HNRNPAB,AGTRAP,IFT27,PARN,WRNIP1,SUB1,VASP,ZNF639,GRSF1,FUT8,AKAP8,FAM89B,PDS5B,GTSE1,MRPL54,POLR1B,ASB6,FGFR1OP2,ABCC1,PREB,SAP30,IFRD1,KAT7,USP42,PSMG1,ADRB2,DNAJA1,RHOB,MAGED2,PPP2R5A,RBL1,PSMD3,RPS14,PRPS2,STX18,CDCA5,PML,FBXL3,CDK2,RNF114,ADAM23 |
| 1.015e-03 | -6.89 | GSE39820_CTRL_VS_IL1B_IL6_IL23A_CD4_TCELL_UP | MSigDB lists | GSE39820_CTRL_VS_IL1B_IL6_IL23A_CD4_TCELL_UP | 194 | 46 | 17377 | 2626 |
PARP12,ADAM10,PTTG1,RRM1,SMC6,XPO7,PPP1R16B,TFRC,RFWD3,RPA2,UBXN2A,CTSS,MCM5,IL6ST,PHF14,RCSD1,TPST1,NAA50,TARDBP,CYC1,ZNF770,MSH6,ACSL5,MND1,ERMP1,FOXK1,TLK1,TEX10,TBRG4,RAB3IP,TWISTNB,RDH11,SLC19A1,POLE,CHD3,PTER,ITGB1,CAB39,BAZ1B,CNOT6,KPNA2,BEND3,NAA20,TRAF5,PTDSS1,PDCD4 |
| 1.015e-03 | -6.89 | GSE45365_NK_CELL_VS_CD8A_DC_UP | MSigDB lists | GSE45365_NK_CELL_VS_CD8A_DC_UP | 194 | 46 | 17377 | 2626 |
DYNLL1,WDR13,UBE2Q1,RRAGC,MAN2B1,SNN,TCF19,SAFB2,C19orf48,GNB2,BCAP31,RBM4,MXD1,MLX,KLF16,SNX18,MTMR4,ARF5,IL6ST,PHTF1,CORO1A,TTLL12,PDIA6,FAM171A1,TGFB1,FTL,PPT1,PIP4K2C,HEBP2,HTATIP2,EMP3,ARHGDIB,ESYT1,PTTG1IP,MPG,LY6E,SEC31A,HGS,SEC23IP,DCK,KHSRP,NCLN,SNRPG,AKNA,SMAD1,MYL12B |
| 1.016e-03 | -6.89 | protein dephosphorylation | biological process | GO:0006470 | 193 | 46 | 17256 | 2622 |
CTDP1,PPP1R12A,EYA1,PPP1R15B,PTP4A3,CYCS,PPP3CB,DUSP22,UBLCP1,PTPN2,PPP1R3B,PDXP,PTEN,MTMR4,PPP4R1,PPP6C,PTPN11,BCL2,CDC25B,MINPP1,RPRD1B,ILKAP,CTDSP2,CAMK2G,TIMM50,PTPRK,PPP3CA,PTPN18,RPRD1A,NCK1,MTMR6,STYXL1,MTMR3,PTPRF,PPP2CA,PPP2R5A,DUSP3,PPM1G,PTPN7,PPP3R1,PPA2,DUSP11,PTPDC1,PPP5C,EYA2,PPP2R2D |
| 1.016e-03 | -6.89 | zf-RanBP | pfam domains | PF00641 | 16 | 8 | 17054 | 2545 |
MDM2,EWSR1,NEIL3,NUP153,ZRANB2,FUS,ZRANB1,RYBP |
| 1.019e-03 | -6.89 | AP1B1 (adaptor related protein complex 1 subunit beta 1) | protein interactions | 162 | 87 | 26 | 17029 | 2761 |
PRKAB1,GPBP1L1,TRIP10,PRKDC,CUL3,EPN1,ARF1,CCNL2,AP1B1,NECAP2,RPA1,PIP5K1C,RPA2,SMAD2,SHC1,ARF5,AP1M1,AP1S1,GTSE1,CABIN1,PPP6R2,PPP6R3,ARRB2,CDK2,AP2S1,CDC5L |
| 1.021e-03 | -6.89 | blastocyst development | biological process | GO:0001824 | 60 | 19 | 17256 | 2622 |
GINS1,SP3,NASP,XAB2,SF3B6,CUL3,RTF1,ZP3,CNOT3,GINS4,PSMC4,MFN2,CAPN2,PALB2,DAD1,CTR9,ZNF830,BYSL,PRPF19 |
| 1.021e-03 | -6.89 | establishment of vesicle localization | biological process | GO:0051650 | 230 | 53 | 17256 | 2622 |
KIF3B,DNAJC5,RAB11B,GORASP1,DCTN2,TRAK1,AP3M2,KIF23,AP3S1,SEC16A,PSEN1,RAB11A,PIP5K1C,KIF5B,ANKRD28,CDK5,CD59,AP3S2,RIMS3,SEC24C,PPP6C,DNM2,KIFAP3,LMAN1,TFG,SYTL3,PPP6R1,MYO5A,TMED2,PREB,DCTN1,USO1,TRAPPC9,CUL3,MCFD2,RAB1A,PEF1,SEC31A,SEC23IP,PDCD6,GOLGA2,NSF,TMED10,SNAP29,SNAP23,EXOC4,NDE1,PPP6R3,CLN3,UNC13C,CSNK1D,STARD3NL,SNAPIN |
| 1.022e-03 | -6.89 | skin-malignant_melanoma-superficial_spreading | COSMIC cancer mutations | skin-malignant_melanoma-superficial_spreading | 31 | 12 | 17385 | 2587 |
FGFR3,RB1,EWSR1,NRAS,PTEN,SF3B1,RAC1,STK11,KRAS,MEN1,HRAS,CDKN2A |
| 1.022e-03 | -6.89 | GO_SNRNA_METABOLIC_PROCESS | MSigDB lists | GO_SNRNA_METABOLIC_PROCESS | 74 | 22 | 17377 | 2626 |
INTS2,EXOSC6,POLR2I,RPRD1A,POLR2G,POLR2L,POLR2K,ELL2,POLR2D,EXOSC9,SRRT,SNAPC4,POLR2A,GTF2F1,CCNK,EXOSC7,POLR2J,INTS7,INTS1,INTS12,TAF6,RPRD1B |
| 1.028e-03 | -6.88 | cell division site part | cellular component | GO:0032155 | 66 | 20 | 18223 | 2701 |
MZT1,RHOA,RHOC,TUBGCP5,MYH9,RACGAP1,SEPT7,MEN1,ICAM2,ANLN,RAB11A,TUBGCP2,RHOB,RTKN,MASTL,PDXP,RAB21,CEP55,ITGB1,NDE1 |
| 1.031e-03 | -6.88 | G1/S-Specific Transcription | REACTOME pathways | R-HSA-69205 | 18 | 9 | 10287 | 1696 |
PCNA,CDT1,TFDP1,E2F1,RRM2,CDC6,ORC1,TFDP2,FBXO5 |
| 1.036e-03 | -6.87 | RNF144A (ring finger protein 144A) | protein interactions | 9781 | 15 | 8 | 17029 | 2761 |
UBE2V1,E2F2,PRKDC,E2F4,USP21,USP32,E2F1,E2F3 |
| 1.036e-03 | -6.87 | JAGN1 (jagunal homolog 1) | protein interactions | 84522 | 15 | 8 | 17029 | 2761 |
SEC61A1,DDOST,VDAC2,TMEM216,VKORC1,TECR,APP,LMNA |
| 1.036e-03 | -6.87 | RNF135 (ring finger protein 135) | protein interactions | 84282 | 15 | 8 | 17029 | 2761 |
DDX58,KLHL42,RNF135,GOLGA2,GTF2H2,XRCC4,TACC3,TXLNA |
| 1.036e-03 | -6.87 | EHBP1L1 (EH domain binding protein 1 like 1) | protein interactions | 254102 | 15 | 8 | 17029 | 2761 |
RAB8A,TFG,HNRNPR,MTA2,POLR2A,PPP4R1,RBM8A,SPTAN1 |
| 1.036e-03 | -6.87 | MAEL (maelstrom spermatogenic transposon silencer) | protein interactions | 84944 | 15 | 8 | 17029 | 2761 |
HNRNPA2B1,KHSRP,YBX1,SYNCRIP,DDX39A,PABPC1,NUDC,FUBP1 |
| 1.036e-03 | -6.87 | PPP1R14A (protein phosphatase 1 regulatory inhibitor subunit 14A) | protein interactions | 94274 | 15 | 8 | 17029 | 2761 |
CSNK1G2,CSNK1G1,YWHAZ,CSNK1A1,APP,CSNK1D,CSNK1G3,PRNP |
| 1.037e-03 | -6.87 | tRNA processing in the nucleus | REACTOME pathways | R-HSA-6784531 | 60 | 20 | 10287 | 1696 |
RPP25,NDC1,NUP188,RAE1,NUP54,NUP155,C2orf49,NUP205,NUP210,POP7,NUP107,RTCB,NUP62,NUP153,CPSF4,TSEN15,NUP85,NUP58,AAAS,SEH1L |
| 1.037e-03 | -6.87 | VANTVEER_BREAST_CANCER_ESR1_DN | MSigDB lists | VANTVEER_BREAST_CANCER_ESR1_DN | 226 | 52 | 17377 | 2626 |
CCNC,SKA3,HJURP,UGP2,C1orf112,SRGN,UCK2,CDCA8,CHIC2,KIF2C,AGFG1,BLM,SNN,LYN,QSOX2,BIRC2,SH3BP1,MCM5,DAPK1,YBX1,PDIA6,FAM171A1,IMPA2,LDHB,IFRD1,MAPRE2,NASP,TNFAIP3,PRIM2,NCK1,AMD1,MEMO1,MYBL2,HEBP2,PSMG1,ANLN,ODC1,EML4,RBM38,OPTN,ZNF777,SYNCRIP,CORO1C,CEP55,TBPL1,CEBPG,RBMS1,UQCRH,PDXK,CCNB2,PFKP,RNF114 |
| 1.045e-03 | -6.86 | GSE21360_NAIVE_VS_QUATERNARY_MEMORY_CD8_TCELL_DN | MSigDB lists | GSE21360_NAIVE_VS_QUATERNARY_MEMORY_CD8_TCELL_DN | 189 | 45 | 17377 | 2626 |
DDX58,DDX47,PARP12,TAP1,XIAP,ADPGK,DUSP22,BZW2,CDC73,PNO1,MIS12,CREM,SLC31A1,HOMER1,PSMA6,SP100,KLHL20,ZCCHC2,DCP1A,INTS12,TNPO2,BCAP29,MOB1A,EIF5,NIPAL3,TRAFD1,ETV3,LAP3,COQ10B,DENND1B,NOL8,ARPC1A,GOSR1,MAK16,ISG15,TMEM127,FBXO28,NIP7,ZNF330,TIMM17A,CSNK1G1,PML,AEN,EHD4,NGLY1 |
| 1.045e-03 | -6.86 | GSE37301_MULTIPOTENT_PROGENITOR_VS_CD4_TCELL_DN | MSigDB lists | GSE37301_MULTIPOTENT_PROGENITOR_VS_CD4_TCELL_DN | 189 | 45 | 17377 | 2626 |
UGP2,WDR13,MDH2,NIT2,SLC29A1,DAZAP2,PRKACA,IFT27,EBP,PRKD3,MLX,CS,MRPL34,ANKRD13C,ZBTB22,SMARCE1,NAA35,MTPN,HP1BP3,FTL,TIMP2,ACP2,SEPT9,SIGMAR1,PPP1R21,ATP2C1,HTATIP2,WBP1,NDRG3,HAGH,SLC50A1,FKBP3,ANKRD46,RPA1,SH3BP5,FBXO21,TIMM13,PDLIM1,STK38,PRDX5,ITGB1,CRCP,PGAM1,NRBP1,CPEB2 |
| 1.045e-03 | -6.86 | GSE15930_NAIVE_VS_72H_IN_VITRO_STIM_IFNAB_CD8_TCELL_UP | MSigDB lists | GSE15930_NAIVE_VS_72H_IN_VITRO_STIM_IFNAB_CD8_TCELL_UP | 189 | 45 | 17377 | 2626 |
RECQL,KLHL21,PHRF1,RAE1,GADD45G,STRN4,UCK1,PCSK7,AP1B1,SPR,C19orf48,APP,SUB1,ZKSCAN1,SIAH1,DDA1,CRY2,CLTB,USP34,METTL1,TMEM115,TIMP2,CREG1,MAP4K3,ADRB2,WBP1,AZI2,ICAM2,SOX4,EIF4H,POLG2,USP21,SF3A2,SPPL2B,BSDC1,PI4K2A,SURF4,CANT1,PITPNA,PSAP,DVL1,SPRYD4,BRWD3,USF2,EYA2 |
| 1.047e-03 | -6.86 | GSE6259_CD4_TCELL_VS_CD8_TCELL_DN | MSigDB lists | GSE6259_CD4_TCELL_VS_CD8_TCELL_DN | 163 | 40 | 17377 | 2626 |
DDX58,OTUD5,PTMS,PDCD6IP,CDS2,GOLPH3L,POC1A,FAM129A,CERK,CLCC1,SNN,SCYL2,ARID1B,COPG2,MXD1,CAPN2,MDM2,LPIN2,SLC44A1,PPP4R1,FNIP2,PLCL2,RNF135,CLN6,ARID4A,PACS2,TRIM14,CYFIP1,ARHGAP17,GALNT7,HERPUD2,OGFR,ATP6V1D,JAK1,SNAP23,UBXN2B,NLRC5,EHD4,PFKP,TMEM131 |
| 1.050e-03 | -6.86 | SMAD_FHA_dom_sf | interpro domains | IPR008984 | 52 | 17 | 18492 | 2768 |
CEP170B,AGGF1,FOXK1,MKI67,IRF3,TCF19,IRF5,AFDN,STARD9,IRF4,SMAD2,KIF14,PPP1R8,KIF13B,CHEK2,SMAD1,SMAD4 |
| 1.050e-03 | -6.86 | PID_PRL_SIGNALING_EVENTS_PATHWAY | MSigDB lists | PID_PRL_SIGNALING_EVENTS_PATHWAY | 23 | 10 | 17377 | 2626 |
CCNA2,RHOA,RHOC,RAC1,ITGB1,PTP4A3,ROCK1,MAPK1,CDK2,MAPK3 |
| 1.050e-03 | -6.86 | EGUCHI_CELL_CYCLE_RB1_TARGETS | MSigDB lists | EGUCHI_CELL_CYCLE_RB1_TARGETS | 23 | 10 | 17377 | 2626 |
KIF18A,CCNA2,MCM5,CDCA8,HMGB2,SMC2,MCM2,KIF11,NCAPG,SMC4 |
| 1.050e-03 | -6.86 | GNF2_MSN | MSigDB lists | GNF2_MSN | 23 | 10 | 17377 | 2626 |
TGFB1,WAS,CDC42,ARPC5,ADAM10,STAT6,ACTR3,CAPZA1,EMP3,OSTF1 |
| 1.050e-03 | -6.86 | BIOCARTA_MTOR_PATHWAY | MSigDB lists | BIOCARTA_MTOR_PATHWAY | 23 | 10 | 17377 | 2626 |
PDPK1,PPP2CA,FKBP1A,TSC1,PDK2,MKNK1,TSC2,PTEN,EIF4G2,EIF3A |
| 1.050e-03 | -6.86 | GO_PROTON_TRANSPORTING_V_TYPE_ATPASE_COMPLEX | MSigDB lists | GO_PROTON_TRANSPORTING_V_TYPE_ATPASE_COMPLEX | 23 | 10 | 17377 | 2626 |
ATP6V0B,ATP6V1D,ATP6V0A1,ATP6V0A2,ATP6V0C,ATP6V1B2,ATP6V1C1,ATP6V0E1,ATP6V0D1,ATP6V1G1 |
| 1.057e-03 | -6.85 | PSMD14 (proteasome 26S subunit, non-ATPase 14) | protein interactions | 10213 | 110 | 31 | 17029 | 2761 |
TXNL1,TXN,PSMA8,PSMB7,PSMA1,BRCA1,MCFD2,SPDL1,PSMD9,PSMB9,PSMB3,UBLCP1,PSMC4,RAD23A,PTPN2,PSMD2,PSMA6,PSMD1,HUWE1,CHD3,UCHL5,PSMD8,PSMD3,RAD23B,E2F1,UBE3C,COPS6,ECPAS,PSMC1,POC5,DCTN1 |
| 1.059e-03 | -6.85 | WAKASUGI_HAVE_ZNF143_BINDING_SITES | MSigDB lists | WAKASUGI_HAVE_ZNF143_BINDING_SITES | 56 | 18 | 17377 | 2626 |
TDP1,RECQL,ERCC1,POLK,PRKDC,PMS2,BRCA1,FANCE,NEIL2,RAD23A,FANCL,RAD18,POLE,RAD23B,MSH2,CHEK2,DDB1,MSH6 |
| 1.059e-03 | -6.85 | REACTOME_REGULATION_OF_APOPTOSIS | MSigDB lists | REACTOME_REGULATION_OF_APOPTOSIS | 56 | 18 | 17377 | 2626 |
PSMA8,MAGED1,PSMB7,PSMA1,PSMB9,PSMD9,APPL1,PSMB3,DAPK3,PSMC4,PSMD2,PSMA6,PSMD1,RPS27A,PSMD3,PSMD8,DAPK1,PSMC1 |
| 1.059e-03 | -6.85 | CAFFAREL_RESPONSE_TO_THC_24HR_5_DN | MSigDB lists | CAFFAREL_RESPONSE_TO_THC_24HR_5_DN | 56 | 18 | 17377 | 2626 |
FOXM1,MCCC1,RRM2,NUSAP1,SEC16A,RBM4,YY1AP1,COPB2,ARF4,EBP,CALM2,SUB1,CDC42,DUT,ZRANB2,EIF5,UBE2C,PCBP2 |
| 1.059e-03 | -6.85 | GO_REGULATION_OF_PHOSPHOPROTEIN_PHOSPHATASE_ACTIVITY | MSigDB lists | GO_REGULATION_OF_PHOSPHOPROTEIN_PHOSPHATASE_ACTIVITY | 56 | 18 | 17377 | 2626 |
ANKLE2,PPP1R12A,PPP1R2,ENSA,PAWR,MASTL,FKBP1A,CALM2,TSC1,PPP2R5A,PPME1,PPP1R11,CRY2,ROCK1,PPP6R3,IGBP1,PPP6R1,PPP2R2D |
| 1.059e-03 | -6.85 | REACTOME_ACTIVATION_OF_THE_MRNA_UPON_BINDING_OF_THE_CAP_BINDING_COMPLEX_AND_EIFS_AND_SUBSEQUENT_BINDING_TO_43S | MSigDB lists | REACTOME_ACTIVATION_OF_THE_MRNA_UPON_BINDING_OF_THE_CAP_BINDING_COMPLEX_AND_EIFS_AND_SUBSEQUENT_BINDING_TO_43S | 56 | 18 | 17377 | 2626 |
RPS15,RPS2,EIF3D,RPS10,RPS24,EIF4H,EIF3G,RPS9,RPSA,EIF3H,EIF3A,EIF3K,EIF2S2,RPS27A,RPS14,FAU,PABPC1,RPS26 |
| 1.059e-03 | -6.85 | GO_PRERIBOSOME | MSigDB lists | GO_PRERIBOSOME | 56 | 18 | 17377 | 2626 |
PPAN,RPLP2,EBNA1BP2,UTP3,MAK16,RPSA,RRP36,KRR1,NSA2,UTP20,UTP18,TBL3,NOC2L,RPLP1,RRS1,FBL,PDCD11,FTSJ3 |
| 1.062e-03 | -6.85 | cytoskeleton organization | biological process | GO:0007010 | 1053 | 196 | 17256 | 2622 |
FGFR1OP,PDCD6IP,NPHP4,ADD1,AGRN,NF1,XIAP,CNTROB,KIF2C,AGFG1,CCNB1,S1PR2,BIRC2,DST,KIFC1,CDK5,NEK6,CDC42,SYNM,DPYSL2,DNAAF2,XRCC2,MAST2,CARMIL1,TACC3,PLK1,PLK3,RHOBTB3,SEPT9,NCK1,FOPNL,EZR,AURKB,BRCA1,ANLN,ZMYM3,EPB41,DPYSL3,SEPT1,WAS,BRWD1,KIF18B,CHD3,LIMK1,AXIN1,E2F4,MAP4,MYO18A,ITGB1,ACTB,CHEK2,DVL1,ROCK1,VPS4A,SASS6,PPP1R12A,RHOC,DNAAF5,CIB1,KIF23,MEF2A,HAUS4,RACGAP1,NCKAP1,ITGB5,HAUS2,LMNA,JMY,SPAG5,CFLAR,RTKN,TMEM250,PDXP,VASP,CCP110,ARPC5,BCL2,ZRANB1,MCPH1,GCC2,WDR1,CAMSAP1,MYBL2,SEPT8,MAP7D1,KRAS,SEPT7,ARPC1A,RHOB,HAUS8,PCM1,GOLGA2,ODF2,ARAP1,SLC16A1,NUP62,NDE1,RUFY3,CDK2,BCCIP,ZNF207,RHOG,WASF2,NDC1,CORO7,ATXN3,TRIP10,POC1A,RAF1,ANK3,ACTR3,RAC1,TPX2,MYH9,NUF2,TWF2,STMN1,SHC1,SH3BP1,ABRAXAS2,KIF14,PIN1,SEPT11,CORO1A,CEP63,RNF19A,ABI1,CFL1,DCTN1,CHP1,ARHGAP17,PSRC1,BIRC3,MKLN1,INTS13,CUL3,TUBGCP5,WIPF1,NUSAP1,BICD2,ERBIN,EML4,KIF2A,CORO1C,GOLGA8A,TRIM32,PARD3,DYNC1LI2,TUBB,CSNK1D,KIF3B,MZT1,MECP2,DCTN2,ARFIP2,PAWR,SPDL1,CSNK1A1,RAB11A,TUBGCP2,MAD2L2,SAPCD2,PIP5K1C,FBXO5,STARD9,PDCD10,ADD3,KLHL20,CENPJ,PRC1,ARHGEF2,CNN2,TTC17,MICAL3,SPTAN1,PDPK1,PPP1R9B,RHOA,STRIP1,TACC1,ASPM,NEK7,ATP2C1,ZMYM5,KIF11,MARK2,INF2,KIF18A,BIRC5,CCDC6,ELMO1,CCDC69,PKD2,WDR62,BRWD3,ESPL1 |
| 1.063e-03 | -6.85 | GO_P53_BINDING | MSigDB lists | GO_P53_BINDING | 65 | 20 | 17377 | 2626 |
PLK3,BCL2L12,USP7,CDKN2AIP,TP53RK,BRD4,EHMT1,USP10,RFFL,SMARCA4,PTTG1IP,BLM,RFWD3,CDK5,MDM2,BRD7,STK11,TP53BP2,ZMAT3,CDKN2A |
| 1.063e-03 | -6.85 | GO_HETEROCHROMATIN | MSigDB lists | GO_HETEROCHROMATIN | 65 | 20 | 17377 | 2626 |
DNMT3A,H2AFZ,MPHOSPH8,BAZ2A,KDM4A,SUZ12,MECP2,TOP2B,SIRT2,MBD3,TRIM28,CBX3,PHC2,MBD2,UHRF2,BAZ1B,H2AFY,BEND3,DNMT1,CDKN2A |
| 1.063e-03 | -6.85 | SMITH_LIVER_CANCER | MSigDB lists | SMITH_LIVER_CANCER | 43 | 15 | 17377 | 2626 |
TMEM106C,RHOBTB3,PPP2R5A,TNFAIP3,HJURP,RAB4A,CENPF,PGRMC1,SDC2,HTATIP2,TP53BP2,PMVK,TOB1,NCOA2,IMPA2 |
| 1.063e-03 | -6.85 | PID_FANCONI_PATHWAY | MSigDB lists | PID_FANCONI_PATHWAY | 43 | 15 | 17377 | 2626 |
FANCL,RPA2,RFC3,PALB2,H2AFX,TOP3A,XRCC3,BRCA1,BLM,RFC2,FANCE,RMI1,WDR48,FANCI,RPA1 |
| 1.063e-03 | -6.85 | ODONNELL_TARGETS_OF_MYC_AND_TFRC_DN | MSigDB lists | ODONNELL_TARGETS_OF_MYC_AND_TFRC_DN | 43 | 15 | 17377 | 2626 |
MND1,CCNA2,DEPDC1,BIRC5,FOXM1,CENPF,DBF4,MYBL2,C4orf46,MYNN,CDC6,AURKB,CCNB1,TFRC,CHAF1A |
| 1.063e-03 | -6.85 | BOYAULT_LIVER_CANCER_SUBCLASS_G123_UP | MSigDB lists | BOYAULT_LIVER_CANCER_SUBCLASS_G123_UP | 43 | 15 | 17377 | 2626 |
GINS1,PON2,SGCE,MRPL9,ATAD2,SHC1,PRKDC,SNRPB,ACLY,RBM3,KPNA2,MAP4K3,CCNB2,SAC3D1,SMC4 |
| 1.067e-03 | -6.84 | GSE6674_UNSTIM_VS_PL2_3_STIM_BCELL_DN | MSigDB lists | GSE6674_UNSTIM_VS_PL2_3_STIM_BCELL_DN | 158 | 39 | 17377 | 2626 |
CHMP2A,FEZ2,GOLPH3L,PPP1R15B,RHOC,UBE2Z,DNAJB1,BLM,ELMOD2,BCAP31,APP,NDUFS4,GNS,MDM2,ITGB8,JAZF1,CENPJ,RABGAP1L,FBXO7,H2AFY,TCEA1,NAP1L4,PLCL2,DNMT1,MORC3,ADAM17,CCDC138,TMEM39A,GTPBP4,ODC1,FAS,ALKBH6,KPNA1,SURF4,LUC7L3,SMURF1,PGAM1,ABCA1,LRCH1 |
| 1.072e-03 | -6.84 | MYO1E (myosin IE) | protein interactions | 4643 | 61 | 20 | 17029 | 2761 |
MAPRE1,RAC1,ILF3,MYH9,CUL1,CAPZA2,ANLN,STMN1,RPA1,CAND1,MCTS1,RPA2,ATIC,MYO18A,OSTF1,ACTB,YWHAH,PPA1,MYO5A,SRPK2 |
| 1.072e-03 | -6.84 | B9D2 (B9 domain containing 2) | protein interactions | 80776 | 61 | 20 | 17029 | 2761 |
MOB4,SUGP2,YTHDF3,RCOR1,PCGF1,ARID1B,MATR3,MTR,EIF4ENIF1,ZNF326,NUP107,ANP32A,NUP153,RBM12B,FAM208A,DNMT1,NUP85,NUP58,HNRNPM,SRSF10 |
| 1.072e-03 | -6.84 | Cdc26 (cell division cycle 26) | protein interactions | 66440 | 61 | 20 | 17029 | 2761 |
SCAMP3,UBR2,MECP2,RRM2,ANAPC2,CDC23,PRDX1,FBXO5,CDC16,KIF18A,CDC27,MRPL55,PRDX3,HPS5,TTC9C,PITPNA,ANAPC7,ANAPC4,CDKN2A,PARD3 |
| 1.072e-03 | -6.84 | USP34 (ubiquitin specific peptidase 34) | protein interactions | 9736 | 61 | 20 | 17029 | 2761 |
UNK,UBQLN4,SNRNP200,UFC1,UBXN1,LAGE3,UBE2V1,UBE4B,UBQLN2,ATP6V1B2,PCGF1,CSNK1A1,STAM,SRXN1,ZRANB2,RBM3,TTLL12,AHCYL1,UBE2C,SSSCA1 |
| 1.072e-03 | -6.84 | ATP6V1C1 (ATPase H+ transporting V1 subunit C1) | protein interactions | 528 | 61 | 20 | 17029 | 2761 |
RAB14,NASP,SNX2,PHB2,IVNS1ABP,GSPT2,CDCA3,PAWR,SRSF5,SSR1,SEC31A,IDE,VASP,DNAAF2,STAT1,ATP6V0A2,ANP32E,ATP6V1C1,LUC7L2,VPS29 |
| 1.072e-03 | -6.84 | DST (dystonin) | protein interactions | 667 | 61 | 20 | 17029 | 2761 |
UNK,MAPRE1,ADD1,MYH9,ERBIN,CAPZA2,ANLN,MCM2,SH3BP5,MYO18A,MAPK6,COPS7B,CEP63,MOB1A,CDK2,ECPAS,TERF1,TERF2,DCTN1,CDC5L |
| 1.075e-03 | -6.84 | negative regulation of nitrogen compound metabolic process | biological process | GO:0051172 | 2388 | 414 | 17256 | 2622 |
FGFR1OP,TXN,ZNF496,MAX,H2AFZ,TSC2,KDM4A,TSC22D3,XIAP,YTHDF3,CCNB1,UBE2I,PPP1R16B,RBM4,RIC1,PARK7,CALM2,CDK5,CDKN2C,PA2G4,CIPC,PARPBP,SRSF4,TRA2B,CRY2,FNIP2,SMARCE1,DNMT1,SENP1,SRSF10,BAK1,PLK3,ERCC1,KLF10,AATF,GABPA,PBK,EHMT1,DDX20,AURKB,EIF3A,DOT1L,BRMS1,HHEX,SMAD2,RPS27A,RPS14,LIMK1,AXIN1,PRDX5,OGT,TFDP2,ARRB2,HDAC2,PDCD4,SVIP,HSPH1,GMFG,PRKAA1,DHX9,EIF2AK4,PARN,PSEN1,METTL3,VPS25,CDC73,CNOT3,CFLAR,CD59,TFAP4,FKBP1A,SMC3,MEX3C,KLF16,HDAC7,FBXO7,PHF14,MSH2,DAPK1,MVP,GNAI2,LPCAT1,TNRC18,PABPC1,TERF2,SOCS5,RBM42,ETV3,FOXK1,ZMYND11,MTA2,GTPBP4,ITM2A,BCLAF1,ARID1A,CBFA2T2,FXR1,KDM3A,PHF6,XRCC5,EPRS,PFDN5,ETS2,DUSP3,CSK,RBMX,QARS,CABIN1,YY1,ZNF830,CDK2,RNF139,CDKN2A,EGLN1,ZNF296,PPP1R37,DNMT3A,GGNBP2,RPS6KA1,UBR2,CAST,SUZ12,RAF1,PTTG1,MAGED1,WDTC1,RCOR3,APP,PAIP2,TERF2IP,SPINDOC,APLP2,SHC1,SP100,MTA1,UCHL5,SOCS6,CDKN1B,RBM15,ATF2,GPD1L,CGGBP1,PDCL3,RNF169,SAP30,ERF,EID1,DRAP1,RNPS1,CUL3,CIRBP,DNAJA1,H2AFV,TRIM28,SOCS7,PPP2CA,CHCHD3,ZNF282,CORO1C,HIPK2,H2AFX,STAT1,BEND3,PPP5C,LRP8,POLQ,NCOR2,DEPDC1,SRSF6,MECP2,TCF3,SECISBP2,AKT1S1,BLM,HMG20A,FOXO3,MAD2L2,WWP2,SUV39H2,PTEN,PPP1R8,AXIN2,CITED2,CNOT6L,CREB1,NCOA2,MSH6,TSHZ1,PDPK1,PPP3CA,TNFAIP3,ILF3,ZP3,PICALM,CBX3,SH3BP5,GPS2,ZHX1,PRDX3,PITX1,LRPPRC,PML,KHSRP,PPP1R11,DDX5,HMGB2,PARP10,IGBP1,CPEB2,PURA,RORB,ZBED3,THOC1,NF1,TRIM11,PPP1R15B,FAM129A,ENSA,CSNK2A1,SIRT2,MAPK14,BIRC2,CREM,PRNP,CYREN,GLIS2,EIF4A3,ZNF639,METTL14,JAZF1,ETV6,PIK3R2,NOC2L,OGG1,ARID4A,CCAR1,PTPRK,RYBP,PLK1,SP3,DEAF1,PBXIP1,NCK1,BAZ2A,VHL,RIOX2,GMFB,EZR,CDC6,LRP5,BRCA1,SOX4,PAF1,EIF4ENIF1,TONSL,SOCS4,ZNF268,CHEK2,CLU,ROCK1,DVL1,CLN3,BEND6,RPS26,POT1,ZNF564,UBE2D3,PPP1R2,PHB2,CENPF,UBXN1,CIB1,TIA1,CTCF,MEF2A,DNAJB1,THRAP3,RGS2,TTF1,LYAR,RB1,MLX,NFATC3,TIGAR,MBD2,ZNF746,ARL6IP1,CTR9,TIMELESS,YBX1,MDFIC,MCPH1,ZNF189,CREG1,CIC,OXR1,LDB1,GBA,RTF1,EIF2AK1,DAPK3,ISG15,ZNF174,MASTL,TSC1,MBIP,SYNCRIP,ORMDL2,KLHL15,NFIL3,SIAH2,NUP62,CTSA,ZFP90,RUVBL2,SNRNP70,TOB1,N4BP2L2,USP7,MBD1,ASH1L,MPHOSPH8,FOXM1,SMARCA4,IRF3,LYN,DUSP22,MXD1,PAIP1,RPL11,HNRNPA2B1,SAP130,ZBTB21,MDM2,TNFAIP8,PIN1,PPME1,TARDBP,STRAP,CTDSP2,RLIM,MOSPD1,CHP1,SNX25,PPIF,TIMP2,BIRC3,FAM172A,ZNF500,BTG2,PCGF6,ATXN1,NFATC2,MBD3,DNAJC10,IDE,RBL1,HNRNPR,MAFK,STAT6,STK38,GADD45B,ARNTL,DNAJC17,H3F3A,SMAD4,CBX4,PARD3,MIF,BCL2L12,DNAJC2,UNK,TRIP12,DAP,AGO2,ARID5A,PAWR,NKRF,MXD4,FBXO5,PTPN2,KMT5A,DUS2,H2AFY,BRD7,STAT3,RBM15B,TGFB1,SAMD4B,PPP1R9B,RHOA,PSPC1,ZNF202,PRKDC,HELB,BTAF1,PRKAR1B,RFFL,RCOR1,PRMT2,MEN1,HSPA1B,CNOT9,LEMD2,UPF1,PLAA,BIRC5,E2F1,GLG1,RBPJ,NR2F2,TERF1,HIPK3,IFI16 |
| 1.075e-03 | -6.84 | GSE17721_PAM3CSK4_VS_CPG_8H_BMDC_UP | MSigDB lists | GSE17721_PAM3CSK4_VS_CPG_8H_BMDC_UP | 184 | 44 | 17377 | 2626 |
BCCIP,SYS1,ADD1,TM9SF3,GLUD1,EIF2AK4,WDR5,CHKA,SRXN1,NUP210,DAPK1,RPF2,PDCD2,TTC3,CYB5R1,GLE1,LMAN1,ASB6,TMEM14C,NUDC,BRD4,RNASEH2C,FAM118B,RAB7A,RDH10,MKI67,SREK1,DCUN1D5,ARPC1A,EPB41,NECAP2,MRPL2,WAS,CORO1C,MYO18A,COX7A2L,PRMT7,ADAM9,KPNA2,SNRPG,ARRB2,LONP2,DDB1,PDF |
| 1.075e-03 | -6.84 | GSE17301_CTRL_VS_48H_ACD3_ACD28_IFNA2_STIM_CD8_TCELL_UP | MSigDB lists | GSE17301_CTRL_VS_48H_ACD3_ACD28_IFNA2_STIM_CD8_TCELL_UP | 184 | 44 | 17377 | 2626 |
RWDD1,DYNLL1,LAGE3,CIB1,MOGS,TBC1D13,SLC35B1,SRXN1,FASTKD3,ERH,KLF16,PPME1,MECR,PARL,SEPT11,NFU1,FBL,MRPL11,LRRC59,TMEM14C,FDFT1,BIRC3,ERLIN1,PGS1,PPP1R21,WDR18,POLR2D,PSMB7,ARHGDIB,PLEKHM3,ABHD11,DDX39A,ODC1,SRSF1,SDHB,ATP1A1,LSM6,HAGHL,PITPNA,RBPJ,RNF14,CHID1,SSSCA1,FUBP1 |
| 1.075e-03 | -6.84 | GSE5542_UNTREATED_VS_IFNA_AND_IFNG_TREATED_EPITHELIAL_CELLS_6H_DN | MSigDB lists | GSE5542_UNTREATED_VS_IFNA_AND_IFNG_TREATED_EPITHELIAL_CELLS_6H_DN | 184 | 44 | 17377 | 2626 |
TCF12,LZTR1,ADAM10,AGTRAP,DCAF15,NF1,B4GALT5,RHOC,TMX4,MYH9,ZFYVE21,KLF13,GYG1,MXD4,UBE2I,SLC25A43,FOXO3,PIP4K2A,CFLAR,MAN1A1,DLG5,DNAJC8,MBD2,ADCY9,PPP4R1,MYBL1,CNNM3,ASB6,TRIM14,MYO5A,ERMP1,TACC1,DENND1B,SLC25A22,BRCA1,UEVLD,LIMK1,E2F4,ZDHHC7,DTD1,MBD6,MAP3K5,GLCCI1,YWHAH |
| 1.075e-03 | -6.84 | GSE23505_IL6_IL1_IL23_VS_IL6_IL1_TGFB_TREATED_CD4_TCELL_DN | MSigDB lists | GSE23505_IL6_IL1_IL23_VS_IL6_IL1_TGFB_TREATED_CD4_TCELL_DN | 184 | 44 | 17377 | 2626 |
SEPHS2,NDUFV2,HNRNPAB,PPP1R12A,C1orf112,FAM129A,TKT,DNAJB1,SCYL2,MXD1,SPAG5,C2orf68,TMCC3,LYAR,ANKLE1,PSMD1,PDCD10,CENPJ,KIF22,AHCYL1,SGCB,S100A6,ELOF1,SAP30,TSHZ1,ADAM17,CPOX,WBP2,CDCA2,RTF1,BICD2,CCNF,PEF1,ARL5B,TARS,SEPT1,NSMCE2,PPM1G,MRPL27,H2AFX,KPNA2,TAF12,ZMIZ1,YWHAH |
| 1.075e-03 | -6.84 | GSE19401_PLN_VS_PEYERS_PATCH_FOLLICULAR_DC_UP | MSigDB lists | GSE19401_PLN_VS_PEYERS_PATCH_FOLLICULAR_DC_UP | 184 | 44 | 17377 | 2626 |
TOMM20,THOC1,TCF3,ASAH1,PCSK7,EZH1,CLCC1,GGA2,PDXDC1,LRRC14,CRKL,TET3,PDK2,NDUFV1,MTA1,XPA,AP2B1,TTC3,TECR,PLCL2,PDIA6,GPD1L,USP34,PPP3CA,SEPT9,EID1,DCAF8,NQO2,SUGP2,UBE4B,CADM1,SOX4,PRKRA,RAB22A,SPPL2B,DOT1L,ZMYM3,RPA1,SEC31A,PFDN5,STT3A,STK38,OGT,PDCD4 |
| 1.075e-03 | -6.84 | GSE27786_LIN_NEG_VS_NKTCELL_DN | MSigDB lists | GSE27786_LIN_NEG_VS_NKTCELL_DN | 184 | 44 | 17377 | 2626 |
SART1,RPLP2,DHPS,CXXC1,CAST,PTTG1,GADD45G,TAP1,ARID5A,CTCF,ARGLU1,SECISBP2,CHKB,MYO9B,DAZAP2,EIF1B,SLC20A1,METTL3,GIT2,HMG20A,DDRGK1,CTNNBL1,BDH1,PPP1R12C,EI24,ORAI1,SLC26A2,AQR,TTC17,ATF2,FYTTD1,PIGT,NCK1,PLEC,RIT1,HERPUD2,TAZ,STK38,STX18,DNAJC17,SLC25A19,MBOAT1,NAA60,HIGD2A |
| 1.075e-03 | -6.84 | GSE24142_DN2_VS_DN3_THYMOCYTE_ADULT_DN | MSigDB lists | GSE24142_DN2_VS_DN3_THYMOCYTE_ADULT_DN | 184 | 44 | 17377 | 2626 |
SLC12A7,CCDC93,FAM208B,DNAJC5,TRIP12,C16orf87,CSNK2A1,NCKAP1,LCLAT1,C19orf48,RAPGEF6,PNO1,NDUFS4,PDCD10,IARS,MED10,HUWE1,TIMM23,CS,TPST1,RPF2,RPL22L1,PDPK1,YTHDC1,RCOR1,HERPUD2,KDM3A,DHX57,CYB5A,AKAP1,CHCHD3,PTPRF,PLD3,EIF4ENIF1,HSPB11,PPP2R5A,ETS2,TPP2,U2SURP,ARNTL,SLAIN1,ZMAT3,PURA,TMEM131 |
| 1.075e-03 | -6.84 | GSE21360_NAIVE_VS_TERTIARY_MEMORY_CD8_TCELL_DN | MSigDB lists | GSE21360_NAIVE_VS_TERTIARY_MEMORY_CD8_TCELL_DN | 184 | 44 | 17377 | 2626 |
EXOC3,CORO7,GMFG,ADD1,HABP4,PTTG1,CDCA3,CERK,CDCA8,LAGE3,PCSK7,NENF,CHKB,MYO9B,FKBP2,MAP1LC3B,PIP4K2A,ANKRD28,RBM23,NUP210,DBNDD1,PPP6C,H2AFY,CDC25B,CNN2,RNASEH2A,PACS2,SPSB3,GPX4,DCAF8,UBE4B,EDF1,ESYT1,ELK1,LUC7L,NDRG3,TAZ,SPPL2B,PFDN5,WAS,POLR2J,SPCS3,UBE2C,CCNB2 |
| 1.075e-03 | -6.84 | GSE3720_VD1_VS_VD2_GAMMADELTA_TCELL_WITH_PMA_STIM_UP | MSigDB lists | GSE3720_VD1_VS_VD2_GAMMADELTA_TCELL_WITH_PMA_STIM_UP | 184 | 44 | 17377 | 2626 |
SRM,TCF12,PPCS,NOP2,PHB2,MAGED1,CDK13,TMED3,S1PR2,LCLAT1,RAB11A,SLC25A36,PRNP,NSRP1,PPIG,TTC3,ARID4A,MSH6,TIMM8B,TRIM8,LAP3,ERLIN1,ACSL3,HSDL1,TOR1AIP2,FXR1,ODC1,GAR1,ANKRD46,RPA1,IWS1,ZMYM3,PDLIM1,DCK,LUC7L3,ACAT1,DTD1,ST3GAL2,BEND3,USP11,PGAM1,HIPK3,FAM83G,TMEM131 |
| 1.075e-03 | -6.84 | GSE5589_UNSTIM_VS_45MIN_LPS_AND_IL6_STIM_MACROPHAGE_DN | MSigDB lists | GSE5589_UNSTIM_VS_45MIN_LPS_AND_IL6_STIM_MACROPHAGE_DN | 184 | 44 | 17377 | 2626 |
UGP2,B4GALT5,DYNLL1,METTL3,GFM2,PDXDC1,APOPT1,KIF5B,DECR1,NOL11,INPP5A,UTP18,RAD23B,NAA50,HADHB,ATP6V0A2,DDX31,CLDND1,MARCH2,AHCYL1,NAA35,PPA1,FTSJ3,S100A6,TSTA3,ELL2,C16orf72,TMEM126B,TBRG4,ARHGEF12,PRPF3,OTUD3,ZFAND5,GAR1,CLNS1A,PDCD6,HIPK2,MRPL27,AEN,DUSP11,CHMP7,C7orf26,GPATCH4,FUBP1 |
| 1.075e-03 | -6.84 | GSE360_CTRL_VS_B_MALAYI_HIGH_DOSE_DC_UP | MSigDB lists | GSE360_CTRL_VS_B_MALAYI_HIGH_DOSE_DC_UP | 184 | 44 | 17377 | 2626 |
MPHOSPH8,GNPDA1,SF3B1,RRM1,ENSA,BLM,GGA2,RGS2,RNF103,PIP5K1C,ATG4A,ZNF75D,DNAJC8,SLC1A4,CDC42,DAD1,MEGF8,PPP4R1,ANP32A,AP2B1,TARDBP,AHCYL1,TRIM14,RHOBTB3,MLEC,NSDHL,ATP2C1,PSMB7,LDHA,PRPSAP1,KRIT1,UTP20,CACNB1,DAP3,CHD3,STT3A,MFAP1,SETD3,ODF2,NCOA1,PGAM1,FAM208A,PSMC1,PRPF4B |
| 1.075e-03 | -6.84 | GSE411_WT_VS_SOCS3_KO_MACROPHAGE_IL6_STIM_100MIN_DN | MSigDB lists | GSE411_WT_VS_SOCS3_KO_MACROPHAGE_IL6_STIM_100MIN_DN | 184 | 44 | 17377 | 2626 |
NSMCE4A,ADD1,SCAMP3,PHB2,CAST,CDK2AP2,TMEM109,STRN4,MOGS,KLF13,ARGLU1,COMMD5,SNN,REEP5,EBP,C2orf68,LRRC14,RPN1,TNS3,PDK2,PIK3IP1,ECD,CSTF1,DDX28,ULK3,PPP1R18,SNX2,TMEM126B,ZMYND11,DNAJC9,ARHGDIB,RIT1,CYFIP2,MAPK3,TMEM184C,CDC16,PRDX5,NRM,NAGLU,ARRDC1,ZDHHC7,RNF139,ANAPC4,SNAPIN |
| 1.076e-03 | -6.83 | Non-alcoholic fatty liver disease (NAFLD) | KEGG pathways | hsa04932 | 145 | 38 | 7161 | 1149 |
NDUFA5,NDUFV2,PRKAB1,COX5B,NDUFS1,NDUFB6,UQCR10,RAC1,PRKAA1,NDUFA4,COX4I1,CYCS,SDHA,NDUFS7,NDUFS4,NDUFV1,MLX,NDUFA2,CDC42,NDUFB4,PIK3R2,NDUFB9,NDUFS8,CYC1,NDUFA3,TGFB1,AKT2,NDUFA7,NDUFB1,FAS,SDHB,COX7A2L,NDUFA11,COX8A,COX5A,UQCRH,NDUFS5,MAP3K5 |
| 1.076e-03 | -6.83 | Non-alcoholic fatty liver disease (NAFLD) | KEGG pathways | ko04932 | 145 | 38 | 7161 | 1149 |
NDUFA5,NDUFV2,PRKAB1,COX5B,NDUFS1,NDUFB6,UQCR10,RAC1,PRKAA1,NDUFA4,COX4I1,CYCS,SDHA,NDUFS7,NDUFS4,NDUFV1,MLX,NDUFA2,CDC42,NDUFB4,PIK3R2,NDUFB9,NDUFS8,CYC1,NDUFA3,TGFB1,AKT2,NDUFA7,NDUFB1,FAS,SDHB,COX7A2L,NDUFA11,COX8A,COX5A,UQCRH,NDUFS5,MAP3K5 |
| 1.077e-03 | -6.83 | endometrium | COSMIC cancer mutations | endometrium | 16181 | 2444 | 17385 | 2587 |
HECA,ZBTB10,ABCC10,HEXB,TGOLN2,CCNL2,FBXO22,EEF2K,THAP4,RAD23B,ATP13A3,DNM2,FTSJ3,USP34,CCDC57,ERCC1,NRAS,EHMT1,KIF15,HNRNPF,WDHD1,MIER2,DIDO1,RAB22A,SMAD2,MID1IP1,RPS27A,MYO18A,OGT,MPV17,COX5A,SMAD1,ZNF75A,ANXA11,SLC25A33,ZNF720,SEC61G,GGA1,MUM1,CCZ1,TRIO,RAB23,KCTD17,HAUS4,EIF2AK4,APH1B,PARN,CDC73,MYL6B,ATG4A,TMEM179B,ERV3-1,SMC3,C4orf3,GEMIN4,MVP,NUP85,PPP6R1,PABPC1,NSUN4,PPA1,IFRD1,AGGF1,FOXK1,RBM42,GTPBP4,MAP7D1,MRPL16,ELK1,EIF4H,RDH11,MAGED2,KPNA1,ETS2,TYW5,WIPI2,RUFY3,PDLIM5,ACSF2,FAM72D,RHOG,EXOC3,STARD7,C5orf30,VTI1A,SLC35B2,INO80E,LCLAT1,RCOR3,CPNE3,KIAA1147,RBM23,ZNF420,AHCTF1,TBC1D22A,TBC1D14,GMEB1,NSFL1C,SEPT11,GPD1L,ZC3H3,PDCL3,SNX8,ERMP1,EID1,IDH3A,POLR2D,HTATIP2,MEF2D,TMEM147,GSTCD,TANC1,MAT2A,VPS26B,NSMCE2,CORO1C,CAMKMT,PPP5C,PITRM1,TUBB,COMMD10,ZNF445,HABP4,CCM2,FLOT1,BTN3A1,ATG2B,ABHD14B,PPP1R3B,GOLM1,ZBTB45,HUWE1,ZNF260,NAA50,ANXA5,LTN1,UBE3B,NAP1L4,ZNF710,ST8SIA2,RPL22L1,MED22,SPTAN1,STAU1,DDX24,TCTEX1D2,TACC1,MRS2,LDHA,HEBP2,LLPH,RAB3IP,TTC33,PICALM,SH3BP5,SLC19A1,ACOX1,FAM3C,AEN,PARP10,YWHAH,THAP5,GPATCH4,FAM129A,TRIM11,YTHDC2,SNX15,RBM8A,ENSA,NENF,SND1,RUFY1,TRIM65,ZER1,PRNP,KRR1,RAB8A,NUP210,NT5DC1,NOC2L,EIF5,TACC3,RYBP,VPS13B,PTPN18,MIOS,MBLAC2,SNRPB,CDC6,UTP3,PBRM1,ODC1,USP21,TRAM2,FBXO28,BCL7C,ARRDC1,ADAM9,DVL1,NUMB,ZNF564,C1orf74,CTU2,PARP12,ZCCHC9,CENPF,LAMTOR3,CHCHD2,NCKAP1,LYRM2,RSAD1,TNS3,SUB1,RINL,SSBP3,KIF13B,MBD2,XPA,AHCY,RBM3,GLE1,MRPL48,LRSAM1,HDHD2,NTPCR,NSDHL,AMD1,CAMSAP1,ZNF761,METTL22,ICAM2,STYXL1,APPL1,BBS12,RXRB,SDHB,PCM1,GALNT2,TMEM168,NLRC5,BTBD10,MYO9A,CCNB2,USP7,GLT8D1,RPLP2,SUCLG1,ARID2,TMX4,SLC2A1,ATP6V1B2,PCBP1,LYN,BCAP31,VAV1,TMEM69,MRPL50,PSMA6,ZNF473,ZNF302,BRPF3,TARDBP,BCAP29,CTDSP2,PRPF19,PPIF,KDM3B,MND1,CLCN3,BIRC3,RAB7A,ANKRD33B,PPIE,CHMP2B,VDAC1,EIF3H,TMEM201,GLOD4,IDE,DHX16,UHRF2,XRCC3,CHMP4B,PARD3,BCL2L12,C19orf53,KLHL21,PDAP1,TMX3,CDCA8,GTF3A,ARF1,SLC12A9,TUBGCP2,DNAJB9,HOMER1,POLR1B,RNF5,RBM15B,PPAN,RHOA,RPRD1A,BTAF1,TOP3A,ARHGEF12,PCGF1,DDX23,RAB18,CACNB1,TRIM26,PDCD6,ATP6V1D,L3MBTL3,FAM110A,NEIL3,CTBS,BBX,IMPDH1,TAF12,NR2F2,PGAM1,HIPK3,IFI16,NUP188,TXN,H2AFZ,PNISR,PRKCSH,USP39,UBE2I,SLC25A37,ASPHD2,ZNF428,RAB4A,TRA2B,SUCLG2,CISD2,TAF5L,ZNF800,CDC5L,ZNF524,SGCE,OSBP2,NSUN2,USP22,CLNS1A,EIF3A,ZMYM3,DOT1L,IWS1,ANKRD10,WAS,KIF18B,TPP2,C1orf109,ZMAT3,B4GALT2,PRPF38B,RECQL,C9orf78,EWSR1,GADD45G,RRM1,ACAP1,B4GALT1,CYCS,SUPT7L,TMEM165,NPLOC4,CNOT3,SPAG5,WDR48,RTKN,CEP104,EXOSC7,KLHL5,LRRC8D,MSH2,PIGG,OSTF1,FBXL7,MRPL40,TNRC18,SYTL3,FAM171A1,APOL1,EIF5A,GCC2,PRIM2,ELL2,RDH10,MFNG,RPS24,GORASP2,CAPZA2,ADRB2,CCT8,MTR,PHF6,PFDN5,SLCO4A1,TTC13,GOLGA2,RBMX,MED15,PIAS2,APPL2,SAMD8,NUDT3,CDKN2A,ZNF511,ATXN3,RAF1,KIAA0232,C2orf49,CD320,EPM2A,CCNA2,MTMR4,BRI3,TP53BP2,AQR,RBM12B,ILKAP,CDK12,SAP30,BRD4,DRAP1,NARF,LRRC8A,ELP4,ABHD11,PKMYT1,ASB13,SERP1,TRIM28,SUPT16H,EIF3K,CHMP4A,CBWD1,ATF6,XRCC4,ADAM23,PRPF4B,NDUFS1,DEPDC1,MECP2,SECISBP2,HMG20A,WWP2,JAKMIP1,SLC25A36,CCNK,DNAJC8,AXIN2,JMJD4,ANKRD37,KAT2A,TMEM126B,RABIF,ADSL,PACS1,BMS1,KCNQ1,OTUD3,ARSK,MACF1,KIF11,COMMD4,KLF6,SMAP2,FADD,SH3GLB1,MYO1F,CBX3,TMEM127,INF2,DUSP11,DDX5,WDR62,TAF6,ESPL1,DDB1,DEF6,FAM83G,IPO4,UBL3,NAT9,PIGM,LYRM4,GPR132,UBE2Q1,PTP4A3,BRIX1,MRPL19,ZNF696,SF3B2,PCYOX1L,CDC42,SYNM,GOT2,JAZF1,HADHB,RPF2,SLC35C2,CNNM3,CARM1,SRPK2,WDR41,LARS,ZCCHC10,CCDC138,LRBA,TMEM216,SUMF2,KMT2C,OGFR,PRPSAP1,ASF1B,RPL37,MAN2A2,EIF4ENIF1,NIP7,U2SURP,MIA2,ZNF268,VPS4A,PPP1R2,PM20D2,XPNPEP3,RGS2,LYAR,POLR2I,TRAFD1,SUGP2,GBA,EIF2A,SYVN1,CCDC71L,DAPK3,ARHGAP15,MASTL,UAP1,NFIL3,FN3KRP,YWHAZ,CTSA,TMEM14A,TOB1,TSEN15,ADNP2,TCF12,PRKAB1,MDH2,SMARCA4,ORC1,RRN3,UBXN2A,IARS,CD3EAP,KIF14,EXOSC1,CS,CLTB,CSTF1,POU2AF1,UBQLN4,NXT1,HPDL,PGGT1B,SELPLG,SMU1,ATXN1,GLO1,OGDH,BICD2,CADM1,EDEM2,HERPUD2,TOLLIP,FANCE,MBD3,PDHX,RPS9,ALKBH6,SURF4,DUS3L,ARNTL,ANP32E,FKBP5,TMEM101,CCDC125,ABCA1,PDCD2L,GCLM,RAE1,DCTN2,NUP54,CHIC2,PAWR,MXD4,DCUN1D4,PIP4K2A,XPR1,FERMT3,KIF5B,KLHL20,SEC24C,RRBP1,ARHGEF2,ANP32A,LDLRAD3,STAT3,MYO5A,NIPAL3,TXNL1,PHF20L1,DCAF6,FAM49B,TMEM39A,ATP2C1,RFFL,COG1,RCOR1,PRMT2,TFEB,LEMD2,UPF1,ELMO1,ZC3H7B,DTX4,ZMIZ1,TERF1,HRAS,CCDC93,TMED7,PIGQ,CNTROB,PPP1R16B,MIS12,GSDMB,TTC9C,PDS5B,NUP153,PGAP2,TMEM115,PLEKHM3,DCUN1D5,PLEKHF2,BRMS1,PWWP2B,TRIM47,WDR11,AXIN1,SMG9,TRIM52,LONP2,NDUFV2,PHF23,CERK,SLC4A2,EZH1,ITGB5,LMNA,MCTS1,DDX56,EIF2S2,SLC38A5,FOXN2,CARS2,PRRC2A,C16orf72,RB1CC1,ZMYND11,PGS1,MYBL2,UHRF1BP1,MPG,MATR3,CYB5A,NCDN,POLR2J,SETD3,TEX30,PTAR1,CNOT6,NDE1,EGLN1,ZNF207,ANKRD27,ABCA3,SARNP,IVNS1ABP,RMI2,MON1B,TMEM97,NIT2,NUF2,ZNF267,TMEM161B,APP,PRKD3,CLUAP1,ATP2A2,UTP18,GRSF1,DUT,ZCCHC2,ANAPC7,RNF19A,FAM76B,TMEM9,GCC1,RNF169,ADCY7,ATP6V1G1,ENPP4,RNPS1,CDCA2,FKBP3,GPR137,DDX17,CHCHD3,PEX5,CDC16,HIPK2,MBOAT1,TICAM1,PDXK,ZBTB11,ANXA6,TMBIM4,GMCL1,UBE4A,ETS1,WRB,ZNF92,PNO1,CAPN2,ADD3,SUV39H2,TTLL12,TPCN1,TMX1,LYPLA2,HNRNPM,MFSD12,LDHB,PPP3CA,NUDT8,POLK,JTB,EMP3,MTMR12,ZP3,PDE3B,KIF18A,CCDC6,MAPK6,C4orf46,LY75,SLC25A19,RGL1,PSAP,WDR76,IGBP1,FAF1,SNAPIN,COX15,THOC1,AGRN,GNPDA1,GPBP1L1,PPP1R15B,CSNK2A1,EBNA1BP2,GIT2,BIRC2,ATPAF1,DLG5,ABL2,XRCC2,ZFYVE27,MCMBP,PTPRK,CDC37,METTL1,HARS,GMFB,ESYT1,ANLN,RAB5B,RHEB,DPYSL3,TBC1D17,TIMM13,CDCA4,TONSL,NRM,NAGLU,ACTB,ZNF45,TMUB1,CTCF,ASAH1,DOCK11,CRLF3,ASXL2,LRRC14,NUS1,SLC27A4,MDFIC,MAML1,CYTH1,NQO2,UTP15,EIF2AK1,EIF4G2,ZDHHC3,MOSPD3,ITPRIPL1,CDC27,SNAP23,TBPL1,PRMT7,KCTD7,NDUFA5,CYLD,UGP2,DYNLL1,COPE,HCFC1R1,ZADH2,GGPS1,RPAIN,RAD23A,ATP6V0B,PDK2,STRBP,DUS4L,MRPL34,PDCD2,SLC39A9,CLPTM1,RPL29,RPL35,DNAJC9,MTMR6,NFATC2,KDM1B,ARL5B,USP36,CCDC127,MRPL2,ATP1A1,CLK3,PSMD3,MAFK,CEP55,DNAJC17,ZNF436,NCOA1,SLC25A39,ZC3HC1,ZNF146,ATXN7L2,CDC40,GOLIM4,SMAP1,RRP15,DAP,GNE,SMC6,ARFIP2,NKRF,CHAC2,BZW2,WRNIP1,CENPM,PTGES3,CAMK2G,MLEC,ZNF202,PPWD1,FAM50B,RHOT2,TPD52L2,GOLGA7,TWSG1,PGRMC1,GLG1,FAM126A,RPS6KC1,UBE2C,PPCS,NDUFB6,TMEM41B,ZDHHC8,PLXNA1,CCNB1,SLC20A1,COMMD6,ABHD14A,C14orf119,ASAP2,SNUPN,CNPY4,PLCL2,SEH1L,ATG9A,PBK,MKI67,DDX20,AMDHD2,SLC17A5,GALNT7,CCNF,FOXRED1,RBM47,PTER,WDR4,DHTKD1,TRAF5,HDAC2,PWWP2A,HSPH1,MAPRE1,CHTF18,KIF23,SLC35B1,NOTCH2,PMF1,COPG2,JMY,FKBP1A,SLC31A1,SNX18,CTPS1,ATP6V0A2,PIKFYVE,RNF135,LPCAT1,EEF1D,TMED2,PHF10,FTL,DDX28,SIGMAR1,PIP4K2C,FAM133B,RIT1,PLEC,KDM3A,SF3A2,FAS,EPRS,ZNF777,TMEM54,QARS,TCOF1,CABLES1,NRBP1,DNMT3A,RWDD1,CKLF,TRIP10,SF3B1,RPS6KA1,SUZ12,CAST,RAC1,GPR89A,OLA1,SNN,GNB2,FLAD1,APLP2,KDM2A,TNPO2,CDKN1B,TALDO1,GPX4,ATP13A1,MAPRE2,RFC3,ERF,CUL3,SLBP,KIAA1586,H2AFV,POLG2,GAR1,PSMB9,DHX57,NSA2,HSPA4,MRPL55,JAK1,TBL3,GOLGA8A,SEL1L,H2AFX,KLHDC4,B4GALT3,PDCD11,ATMIN,POLQ,POU3F2,OTUD5,NCOR2,ANKRD13D,PKP4,SCAMP3,BABAM1,CDCA3,SLC25A12,BLM,TMCC3,GTF2F1,RPL17,CRAT,AHSA1,PRC1,UPF2,COPS7B,SLC38A10,CNOT6L,CNPY3,IFT46,TSHZ1,ZFP64,DENND4C,DENND1B,WDR18,RPL8,ILF3,LRRC1,RHOT1,TSR2,MARK2,ECH1,PRDX1,PLD3,NUCB1,GNA12,FBXO21,C1orf131,PRDX3,PFDN4,HNRNPH3,STX18,TFDP1,KHSRP,ASNA1,CPEB2,SSSCA1,VPS29,BYSL,S100PBP,MIB2,PTMS,NOP2,UBN1,DCAF15,NF1,FLYWCH2,ALKBH5,MOGS,UBE2Z,TAF6L,MAPK14,BECN1,SNAPC4,RNF103,BCAT2,MBD4,C18orf32,METTL14,ZNHIT6,IMPAD1,RCSD1,PHTF1,SRI,KIF22,ZBTB22,NFU1,OGG1,TRIM14,ELOF1,COPS8,FYTTD1,TRIM8,RRM2,SOX4,ABHD5,UBTF,CXXC4,PAF1,UEVLD,SPATA2,PQBP1,IARS2,ATXN2L,GALNT10,STARD3NL,RPS15,PIGN,AGTRAP,CIB1,XPO7,SRRT,ZNF449,CAPZA1,GLTP,BCL2,KIFAP3,N4BP2,HP1BP3,VOPP1,THNSL1,ISG15,CAND1,C22orf46,GNAS,TSC1,RBM25,CDCA5,ZFP90,NANP,RBBP4,ZBTB24,SMARCD1,MBD1,WASF2,MMACHC,GNPNAT1,MPHOSPH8,HNRNPUL2,CHD1,MEAF6,C2orf68,CCDC50,AKAP8,PARL,RPN2,CHTOP,FAM3A,F2R,SCYL3,ABI1,HTRA2,MOSPD1,RLIM,FAM172A,ZNF500,PSMB7,NLN,WIPF1,BOLA1,BUD13,NDUFB1,PEF1,EIF3G,BTBD1,TAB2,TULP3,WDR59,CANT1,SCARB1,GAS2,USP11,SMURF1,PPP2R2D,TSPAN5,CDS2,MAGEH1,MRPL42,EYA1,MRPS26,LETMD1,HDDC2,RGS1,MAN1A1,FBXO5,GART,PELO,TANK,BRD7,MRPL11,SAMD4B,ZDHHC18,GTF3C6,POLR3GL,WDR81,MEN1,ZNF407,MFN2,COX8A,ZRANB2,MBD6,SRSF3,ATP6V1C1,IDH3B,TATDN1,TSC2,LACTB2,CMTM6,RBM4,ZNF275,ANKRD39,RPL23A,CDKN2C,NAPG,USF1,DNAAF2,MECR,AP1M1,UPRT,CRY2,ECD,MOB1A,RNF26,TIPARP,LRRC59,RHBDD2,MGAT5,BAK1,ZNF559,RHOBTB3,GABPA,WBP1,NUTF2,ARF4,GINS4,KRIT1,BOLA3,AHNAK,RAD18,PDRG1,RNASEL,CHPF2,OAZ1,PDCD4,SMNDC1,NXT2,HIVEP3,KIAA0100,CLSPN,RHOC,DHX9,PDCD7,PSMD9,HAUS2,COPB2,CD59,TFAP4,RNFT1,MEGF8,RIMS3,FBXO7,EFTUD2,CPSF4,MRPL21,LUC7L2,EIF3L,MTA2,TYW1,USP10,ITM2A,SSR2,MTX1,SFXN5,FNTA,PDLIM1,TXNDC16,ZNF830,TMEM159,MRPL3,ALS2,FAM72A,TRIM41,KARS,NQO1,POC1A,ANK3,PTTG1,TPX2,TBC1D13,GLRX3,STMN1,C19orf48,REPS1,ABHD16A,FBXL6,SH3BP1,MTA1,UBA5,CLCN6,INTS12,C8orf59,RPRD1B,SZRD1,CGGBP1,CPNE1,SEC61B,FAM118B,GOPC,E2F3,CIRBP,RPL38,CRNKL1,PFKFB3,GORAB,RAB1A,GIGYF1,TMEM184C,PPP2CA,KIF2A,CCDC14,LSM6,RNF38,SNRPG,CENPBD1,DMWD,USP13,MZT1,ZFP91,TRMT6,IP6K2,WDR5,SLC25A43,IFT27,PMVK,NEIL2,RRP36,SRXN1,RPA2,PSMD2,CLIC4,PDCD10,CBWD2,COQ4,ITGB8,ARF5,ARHGEF1,FBXL19,GTF2H2,TTPAL,UTP20,MAGT1,GPS2,DBI,MRFAP1L1,CD81,TMEM131,WDR13,FANCI,PAPOLA,CREM,TET3,FANCL,GLIS2,IL6ST,INTS1,POP7,SLC44A1,MTPN,ASB6,PLK1,SEPT9,CELSR2,RBX1,RAD51AP1,ZBED5,CKAP2L,PSMG1,UBE2V1,EAF2,IL12RB1,KRTCAP2,LUC7L,LSG1,NECAP2,TRIM4,ALG3,AGPAT2,CHD3,ZNF367,E2F4,PRPF4,KPNA2,BEND6,CLN3,DNAJC30,FAM208A,NGLY1,POT1,MYL12B,CCDC137,RMND5A,HJURP,PHB2,DNAJB2,FAM53C,SDC2,KLC1,CDK13,ADCK5,COX4I1,DNAJB1,RAB6A,ARID1B,C1GALT1,MLX,UBE2Q2,CCP110,ZNF746,ARL6IP1,CTR9,NIPSNAP1,ABHD2,DCAF8,ACSL3,LDB1,MAP4K3,ARMC8,RBM38,NMT2,IRF5,HAUS8,MBIP,COX7A2L,ZDHHC7,SIL1,FAM122A,DTD1,UNC13C,BCCIP,SART1,TRAF7,NDUFAF2,TOR1AIP1,ZNF416,LAGE3,ZFYVE21,TM9SF3,RRAGC,ZNF121,OIP5,NRF1,WDR44,PPME1,EFCAB11,RPAP1,CABLES2,LMAN1,AHCYL1,TOP1MT,STRAP,SPSB3,ZNF583,SNX25,ARHGAP17,ZNF780B,PPT1,NUP155,DCLRE1C,MRPS14,RHBDF2,SUGP1,RBL1,FASTK,UBXN2B,STK38,AP1S1,SPRYD4,SLC22A23,H3F3A,CHID1,SMAD4,RAD51D,SLC30A9,CMAS,UNK,NADSYN1,HMGN3,NCAPG,SCYL2,FZD6,HERC3,GTPBP3,CTSS,ORC3,RNLS,YTHDC1,ACP2,HMGN5,CSRP1,METTL5,ABCF2,TUFM,RANGAP1,PNPLA8,HAGH,API5,ZFR,SEC23IP,E2F1,USP20,RBPJ,PDCD6IP,MAX,GXYLT1,LUZP1,ADAM10,CXXC1,TSC22D3,AP3M2,CUL1,GYG1,NANS,OAT,MYEF2,ANKRD26,PA2G4,NOL11,FIZ1,ZNF200,MARCH2,SLC26A2,SRP72,KLF10,LACTB,RFC2,RAB2B,PRIM1,MAP3K4,HHEX,LUC7L3,MAP4,MRPL27,BTF3,PTPDC1,NMD3,CCDC59,PTOV1,COX5B,DNAJC5,SCOC,DHPS,POLR2K,ANKH,VAV2,PRKAA1,C16orf87,GSPT2,TATDN3,DLGAP4,PRPF39,PSEN1,ZNF79,PDXDC1,VPS25,NDUFS7,YY1AP1,C12orf10,FAM192A,RPN1,LHX8,ARPC5,ZNRF2,TPST1,DAPK1,PIK3IP1,CYC1,SOCS5,FDFT1,PIGT,EMB,WDR1,ZNF574,C1orf35,EXOSC9,ARID1A,PTTG1IP,FXR1,GOSR1,MAP2K2,TWISTNB,AKAP1,XRCC5,HMGN2,PI4K2A,CAT,DERL1,HSPBP1,MTHFD2,CEBPG,ARAP1,USP32,FAM83D,CABIN1,SMPD4,GPI,CYTIP,REPS2,RAB11B,UROD,SLC39A13,POMP,BCL2L1,NUDT19,DECR1,RALB,SIAH1,ADCY9,LPIN2,MRPS27,SOCS6,TTC3,RNASEH2A,CFL1,ANKLE2,CDC123,VDAC2,ERC1,AMZ2,ANKZF1,RAD51C,ZNF282,DSN1,DDOST,HINT1,DGCR8,SAFB,RWDD4,FTSJ1,LMBR1,NCLN,BEND3,EYA2,DYNC1LI2,MANBA,B4GALT5,SLC41A1,FAM76A,TKT,CBLL1,ARGLU1,LANCL1,POFUT1,FAM8A1,HEATR5B,HLA-A,EBP,RFWD3,NDUFA2,FUT8,FJX1,BTF3L4,PTPN11,MRPL54,FEM1B,RPL19,CNN2,NDUFA3,MTX2,MSH6,PDLIM2,LONRF3,RFXANK,FBXO9,GUF1,RPL32,ZHX1,OAZ2,NDUFS5,WDR91,HIGD2A,POLA2,ZNF76,MTX3,COPA,UQCR10,HMGXB3,PHRF1,ABCB10,COMMD5,MAP1LC3B,DST,RAB35,SIVA1,GPATCH1,TCEA1,DRAM2,DEAF1,SNRNP200,LAP3,NCK1,VHL,SREK1,ARHGDIB,PITPNB,HSPB11,BRWD1,PPM1G,SH3GLB2,CRCP,BAZ1B,ACBD4,STK11,CLU,CHEK2,ZSWIM3,TSTD2,CHPT1,MRPL13,DCAF5,CAPN1,UBE2D3,NSMCE4A,PPP1R12A,ZCCHC8,GORASP1,UBXN1,NACA,RPL15,EPN1,PCSK7,THRAP3,QSOX2,TTF1,NUP205,PRPF18,CHKA,DTL,ZRANB1,SLC12A2,ATP6V0D1,CSNK1G3,CREG1,NUDT4,RPL6,VKORC1,SLTM,EVC2,KLHL15,SIAH2,SLC16A1,EHD4,SNRNP70,C11orf1,APOL2,N4BP2L2,CHMP2A,CORO7,FEZ2,PMS2,UCK2,UCK1,CLCC1,EXT2,MXD1,USP5,HNRNPA2B1,SAP130,NVL,PPP6C,CYB5R1,ZNF770,EBAG9,RNF25,PCGF6,METTL2A,FAM72B,PON2,HNRNPR,HPS5,STAT6,MAPK1,BRD9,TMEM33,NAT14,DNAJC2,TRIP12,SHPRH,SCYL1,VPS45,MYO9B,GFM2,SPPL2A,FASTKD3,FGFR3,PPIG,ZDHHC13,TMEM99,H2AFY,ATG13,NDUFS8,ERI3,FBL,SLC35A1,FRMD8,MICAL3,TGFB1,ELOVL5,HEMK1,TIMMDC1,HELB,PSPC1,MIER1,SCFD2,NDRG3,CDK11A,MEGF9,ACAT1,CENPT,PLOD3,RAB3IL1,ZSWIM6,RAB14,ADD1,MRPS15,KDM4A,XIAP,DHX8,GLUD1,ANKRD23,PABPC4,CALM2,CDK5,PSMD1,NEK6,NSRP1,RABGAP1L,SRSF4,FNIP2,KCNAB2,PCBP2,MLST8,PLK3,ZNF672,MRPL43,HSDL1,MCL1,SMC2,PPFIA3,ICMT,SLC50A1,STOML2,LIMK1,ZNF689,PRDX5,ATE1,MLYCD,ATP6V0C,ST3GAL2,FBXL3,E2F2,PFKP,AAAS,DDX42,SSRP1,MRPL9,MRPS2,STRN4,TOP2B,ZNRF3,TMED3,DDRGK1,RAVER2,GNS,INTS7,INPP5A,MCM5,PHF14,ZNF326,UBE2QL1,NAGPA,TIMM8B,ETV3,TSPYL4,TSPAN31,DHX29,TEX10,MAN1B1,RPS10,CBFA2T2,ABCF1,RHOB,LRRC14B,DTWD1,PTPRF,SCARB2,OSBPL11,CCDC86,DUSP3,SLAIN1,MDH1,HEXA,RNF139,SNX14,ZNF296,TRERF1,UBR2,CHD1L,ACTR3,WDTC1,MYH9,CREBL2,NIPA2,PRKACA,SAFB2,ANKIB1,STAM,ARL6IP6,RAB21,SP100,ZKSCAN1,DDA1,NUP107,ANKRD13C,MAVS,CEP63,TMEM136,ATF2,DCTN1,SHOC2,PSRC1,MAP4K4,WBP2,ATP6V0A1,NUSAP1,NDUFA7,DNAJA1,TAZ,C19orf54,TAF2,SEC61A1,WDR7,RPLP1,CBLN2,FUS,LRP8,COIL,LRCH1,GALK1,ZNF786,RPS2,SESTD1,TRAK1,JMJD6,SIKE1,AKT1S1,KRI1,FBXO3,ERH,GATC,PPP1R8,PRDM4,GTSE1,GEMIN6,DCP1A,SGCB,IMPA2,NUDC,PDPK1,TK1,GUK1,TNFAIP3,GALC,ZNF512,KIAA0930,MRPS10,DDX39A,RPA1,ZNF180,ZNF862,KEAP1,POLE,TATDN2,PITX1,CAPN7,LRPPRC,PML,HMGB2,USF2,ANAPC4,SRM,DDX47,MCCC1,S1PR2,CDIPT,SEC16A,SSR1,LIN9,PCNA,ZNF639,TRMU,PIK3R2,ETV6,TXLNA,PPCDC,FAM86C1,MYBL1,MRPL32,CCAR1,ABCC5,PBXIP1,BAZ2A,TLK1,MRPL12,EZR,LNX2,LRP5,BRCA1,PRKRA,STX16,EPB41,OPTN,SEPT1,SOCS4,QRSL1,PIEZO1,OSGEPL1,GLCCI1,NUDT11,NAA60,GEMIN7,SEPHS2,LZTR1,RACGAP1,PPP3CB,B4GALT4,RLF,RAPGEF6,SNRNP25,RB1,VASP,MED8,VMP1,PPIL2,MEA1,TIMELESS,AHDC1,ALDH18A1,TMEM8A,ABCC1,PREB,TRAPPC9,AACS,MEMO1,KRAS,RTF1,UBE4B,NFATC2IP,LY6E,ARPC1A,ZNF174,PSMC4,GOLGA4,PALB2,SYNCRIP,PRPS2,NIPA1,TIGD2,RNF114,FOXM1,MRPL39,XAB2,SUMO2,DUSP22,COMMD8,RPL11,CSDE1,MDM2,CORO1A,MINPP1,METTL9,POC5,DVL2,GM2A,PSMA8,COQ10B,CPOX,SLC26A6,CYP20A1,PRPF3,RPSA,SRSF1,DNAJC10,ZNF700,SCAP,PLEKHG4B,TIMM17A,TOMM6,FAU,LTA4H,AP2S1,USP53,INTS2,CTDP1,MIF4GD,CDT1,ARID5A,SUMF1,GGA2,AP3S1,CSNK1A1,RMI1,TFRC,PTPN2,STARD9,GSTK1,NDUFV1,SLC1A4,CWC27,SLC35B4,DDX31,ABCD1,RPAP3,CNTN5,SNX2,ZMYM5,CCDC34,CHCHD6,BSDC1,KPNA4,CDKN2AIPNL,FBXO41,BIRC5,TFE3,SNAP29,CDCA7L,PKD2,ACADM,CHMP7,SAT2,GCSH,ZNF496,TMEM109,TAP1,YTHDF3,NHLRC3,IKBIP,EIF1B,ELMOD2,KIFC1,DBNDD1,CYB5RL,PARPBP,RNASEK,CDC25B,PRADC1,DNMT1,NOL12,ORAI2,USO1,AKT2,NOL8,GNG7,AURKB,MCFD2,SLC25A5,ZFAND5,MAK16,STT3A,TMED10,PSMD8,EIF2D,ITGB1,PTPN7,UQCRH,RRS1,ARRB2,RTN3,ZNF598,SVIP,DDX58,WSB2,PPIB,MUT,HLA-E,NDUFA4,MAN2B1,METTL3,CFLAR,NDUFS4,RNF121,MEX3C,KLF16,HDAC7,DAD1,BDH1,PCYT2,GNAI2,ANKHD1,MORC3,TERF2,KCTD20,SEPT8,DCTD,PKM,TOMM40,PATL1,ADSS,SERTAD2,ZFP92,NSF,DCK,ERGIC3,ACLY,LPCAT4,VCPIP1,YY1,PPP6R3,MAP3K5,PPP6R2,RNF14,CDK2,ZC3HAV1,SYS1,ZBTB37,URB2,EIF3D,MAGED1,KLHL18,ADPGK,SLC25A44,AP1B1,SDHA,PHC2,CRKL,MOAP1,TERF2IP,CYHR1,ZNF75D,SHC1,UCHL5,NAA35,TMBIM1,CCT2,CDKN2AIP,MKLN1,HMGN4,LYRM1,GALK2,CDC23,SHCBP1,AP4E1,PRDM11,VEZF1,PPP2R5A,ACYP1,STAT1,PPA2,TRIM32,C1orf112,TCF3,MRI1,BRAP,AGPAT3,MYNN,SDF2L1,SPR,RAB11A,REEP5,FOXO3,MAD2L2,CCDC28A,RBM17,MAT2B,PTEN,CENPJ,TAGLN2,OSTC,PACS2,NCOA2,SMC4,NEK7,NET1,PARP4,TBRG4,ANAPC2,RPL27A,YIF1A,SGSH,HGS,TTLL4,SLC38A7,MFAP1,CCDC69,BRWD3,ESYT2,SKA3,NPHP4,UBE2E2,HNRNPAB,PLXNC1,ST13,TMEM184B,DNAJC24,ZNF107,KIF2C,SLC29A1,AGFG1,SIRT2,FKBP2,USP48,UBQLN2,SNRPD3,CUTC,EDC3,UBLCP1,ZNF804A,RAP1A,THADA,EIF4A3,ATG3,DPYSL2,PPP1R12C,AKR1B1,JOSD1,RP2,TTC4,TECR,ARID4A,FGFR1OP2,TIMM50,TDP1,DPM1,FOPNL,SLC16A7,SLC25A22,STK17B,DHX15,CHAF1A,GEMIN5,COPS6,SASS6,RPS26,PSMC1,SLC12A7,TBC1D12,TM9SF4,ZNF768,UFC1,MED13L,TIA1,MEF2A,EPHX2,PITHD1,RHBDD1,NFATC3,BANF1,BUD31,ZNF335,YBX1,KNTC1,ACAD8,UBE3C,ZNF189,ALDH9A1,KDELR1,TSTA3,CIC,OXR1,SEPT7,TMEM241,NAP1L1,NSMF,ODF2,EXOC4,KIAA1328,NUP62,PITPNA,NAA20,PTDSS1,MZT2B,PDSS2,C7orf26,TMEM106C,IMMT,ASH1L,CHERP,WDYHV1,PLAGL2,CHKB,IRF3,TWF2,PAIP1,ANKRD28,ANKLE1,FARSA,SAR1A,SCAMP4,APOOL,PDIA6,ACSL5,TOR1AIP2,AZI2,GFER,RAD54B,TMEM41A,DAP3,ZNF317,GADD45B,AKNA,CBX4,KIF3B,GOLPH3L,SH2D3A,CASP6,TOR3A,SRGN,DBF4,MFSD10,SAC3D1,CTNNBL1,YIF1B,CLDND1,TTC17,SLC25A1,GINS1,PAQR6,CSNK1G2,TELO2,ADAM17,HMGN1,NASP,ASPM,PPP1R21,PRKAR1B,SYMPK,TARS,SNRPA,MAPK3,HLA-B,ATAD2,PLAA,ZNF330,OSBPL8,KBTBD7,PREPL |
| 1.079e-03 | -6.83 | response to oxidative stress | biological process | GO:0006979 | 367 | 78 | 17256 | 2622 |
TXN,NQO1,RWDD1,PPP1R15B,SIRT2,BECN1,APP,PARK7,PRNP,PDK2,CCNA2,MDM2,PCNA,ATP2A2,DNM2,TRA2B,OGG1,HTRA2,GPX4,PTPRK,PLK3,PPIF,BAK1,ERCC1,PRKRA,ANKZF1,PON2,ALDH3B1,GUCY1B1,STAT6,ARNTL,PRDX5,STAT1,MPV17,ADAM9,PPP5C,MAPK1,HDAC2,GCLM,PRKAA1,PXMP2,CYCS,PSEN1,ETS1,FOXO3,CFLAR,SRXN1,PDCD10,NDUFB4,XPA,DAPK1,NDUFS8,BCL2,TXNL1,STAU1,TNFAIP3,NET1,OXR1,ERO1A,LDHA,GBA,MTR,RHOB,PRDX1,HSPA1B,MAPK3,CAT,KPNA4,PDLIM1,PRDX3,PML,PKD2,MAP3K5,CDK2,CPEB2,ALS2,ADNP2,EGLN1 |
| 1.081e-03 | -6.83 | WDR92 (WD repeat domain 92) | protein interactions | 116143 | 74 | 23 | 17029 | 2761 |
RPAP3,TELO2,CCT2,SNRNP200,TSC2,ZNF316,PPP3CB,CSNK1A1,SEC16A,PMVK,VPS25,CCT8,POLR2A,TERF2IP,TSC1,PDRG1,DNAAF2,WDR4,EFTUD2,RUVBL2,ECD,UBE3C,PPP6R2 |
| 1.081e-03 | -6.83 | MARTINEZ_TP53_TARGETS_DN | MSigDB lists | MARTINEZ_TP53_TARGETS_DN | 551 | 110 | 17377 | 2626 |
RHOG,NDUFA5,MAX,MRPL39,PIGQ,ANK3,AGPAT1,SMARCA4,SAFB2,MIS12,UBLCP1,SF3B2,PRNP,APLP2,STRBP,ATP2A2,SIAH1,SIVA1,MTA1,SLC44A1,RAB4A,PPCDC,RPN2,TARDBP,AQR,TECR,ACSL5,PLK1,CCT2,CLCN3,UBQLN4,CELSR2,AATF,KAT7,TAOK1,MKI67,SREK1,PFKFB3,MCL1,KRTCAP2,TXNL4A,ERC1,CLNS1A,BRD2,TMED10,HIPK2,MAP4,DNAJC17,ATP6V0C,FKBP5,CLU,CHEK2,SNRPG,SMAD1,SMAD4,CCDC137,FUBP1,SEPHS2,PPIB,MIF4GD,ZCCHC9,HJURP,PHB2,PDAP1,DAP,SCYL1,NKD2,MAN2B1,THRAP3,RAB6A,SLC35B1,PDCD7,EPHX2,FZD6,PIP5K1C,TMCC3,LYAR,NDUFA2,HUWE1,EFTUD2,SLC27A4,MAML1,CPSF4,NDUFA3,LPCAT1,LDHB,ZMYND11,ZNF574,TUFM,MYBL2,ILF3,RPS24,PLEC,PTTG1IP,SF3A2,NCDN,POLR2A,PSMC4,RDH11,PTPRF,EPRS,GNA12,GOLGA4,STX18,TFDP1,CEBPG,SRSF3,MAP3K5,RBBP4,HRAS |
| 1.082e-03 | -6.83 | Selenocysteine synthesis | REACTOME pathways | R-HSA-2408557 | 95 | 28 | 10287 | 1696 |
RPS15,RPL29,RPS2,RPL35,RPLP2,RPS10,RPL6,RPL38,RPL8,RPL15,RPS24,SECISBP2,RPL27A,RPS9,RPSA,RPL11,RPL36,RPL23A,RPL37,RPL32,RPS27A,RPL17,RPS14,RPLP1,RPL19,FAU,RPS26,RPL22L1 |
| 1.085e-03 | -6.83 | UL87 (promotes accumulation of late transcripts) | protein interactions | 3077465 | 12 | 7 | 17029 | 2761 |
POLR2I,POLR2G,POLR2L,POLR2J,POLR2K,POLR2A,POLR2D |
| 1.085e-03 | -6.83 | SFSWAP (splicing factor SWAP) | protein interactions | 6433 | 12 | 7 | 17029 | 2761 |
RBM17,JMJD6,EWSR1,CFAP20,NEIL3,CAND1,RNPS1 |
| 1.085e-03 | -6.83 | ARL4A (ADP ribosylation factor like GTPase 4A) | protein interactions | 10124 | 12 | 7 | 17029 | 2761 |
KRAS,KPNA2,CCDC57,GOLGA2,SPATC1L,ELMO1,RAC1 |
| 1.086e-03 | -6.83 | GSE6674_UNSTIM_VS_CPG_STIM_BCELL_DN | MSigDB lists | GSE6674_UNSTIM_VS_CPG_STIM_BCELL_DN | 153 | 38 | 17377 | 2626 |
MMACHC,DNAJC2,NADSYN1,HABP4,SDC2,SLC29A1,SLC20A1,PMVK,ANKRD26,SHC1,DUS4L,NUP107,TRA2B,ABCD1,TALDO1,TTLL12,LMAN1,ALDH9A1,WBP1,LSG1,RBM38,NCDN,HAUS8,PAF1,SLCO4A1,PLD3,SLC38A7,GRIPAP1,CCDC14,MPV17,FTSJ1,LMBR1,FAM126A,DVL1,PDXK,COPS6,NDE1,HIGD2A |
| 1.088e-03 | -6.82 | Actb (actin, beta) | protein interactions | 11461 | 182 | 46 | 17029 | 2761 |
RAB14,IMMT,PPP1R12A,LUZP1,ACTR3,DCTN2,FLOT1,TWF2,SEC16A,MYL6B,XPR1,DST,CDC42,PTEN,ARPC5,CAPZA1,SRI,GTSE1,AP2B1,MVP,CLTB,GNAI2,MICAL3,CSNK1G3,MYO5A,SPTAN1,CPNE1,PPP1R18,OXR1,CAPZA2,RAB1A,ARPC1A,PICALM,CCT8,ERC1,MAT2A,DAPK3,STOML2,CHCHD3,GNAS,INF2,AHNAK,MYO18A,CHMP4B,RUVBL2,ZNF598 |
| 1.091e-03 | -6.82 | REACTOME_GLYCEROPHOSPHOLIPID_BIOSYNTHESIS | MSigDB lists | REACTOME_GLYCEROPHOSPHOLIPID_BIOSYNTHESIS | 79 | 23 | 17377 | 2626 |
CDS2,PGS1,AGPAT1,AGPAT3,CHKB,PITPNB,PNPLA8,CDIPT,TAZ,LCLAT1,CHKA,PLD3,AGPAT2,SLC44A1,LPIN2,LPCAT4,HADHB,MBOAT1,PCYT2,LPCAT1,GPD1L,CHPT1,PTDSS1 |
| 1.091e-03 | -6.82 | RNA polymerase II transcribes snRNA genes | REACTOME pathways | R-HSA-6807505 | 73 | 23 | 10287 | 1696 |
INTS2,POLR2I,RPRD1A,POLR2G,POLR2L,POLR2K,ELL2,INTS13,POLR2D,SRRT,SNAPC4,POLR2A,GTF2F1,CCNK,POLR2J,INTS7,INTS1,NABP2,NABP1,INTS12,ICE2,TAF6,RPRD1B |
| 1.095e-03 | -6.82 | CHCHD2 (coiled-coil-helix-coiled-coil-helix domain containing 2) | protein interactions | 51142 | 101 | 29 | 17029 | 2761 |
COX5B,LYRM4,COQ8A,COQ10B,CHCHD2,NDUFA4,ADCK5,PRPF3,XPNPEP3,FAM136A,TOMM40,ATP5PF,SDHA,CHCHD6,ECH1,IDE,GOLGA2,COQ4,GRSF1,PPA2,COX5A,KHSRP,PRPF4,SPRYD4,ATP5F1A,APOOL,PITRM1,TIMM50,NIPSNAP1 |
| 1.095e-03 | -6.82 | LMNB1 (lamin B1) | protein interactions | 4001 | 101 | 29 | 17029 | 2761 |
COX15,CASP6,URB2,SRSF6,TOR1AIP1,RAC1,DCTN2,ILF3,SMARCA4,BRCA1,PLEC,ADRB2,MCM2,VDAC1,MAP1LC3B,SDHA,GIT2,LMNA,RPA1,MBIP,KPNA4,KPNA1,MAGT1,PIAS2,GNAI2,HNRNPM,HP1BP3,SRPK2,SPTAN1 |
| 1.100e-03 | -6.81 | Citrate cycle (TCA cycle, Krebs cycle) | KEGG pathways | hsa_M00009 | 22 | 10 | 7161 | 1149 |
SDHB,SUCLG1,MDH2,IDH3A,CS,SUCLG2,MDH1,OGDH,IDH3B,SDHA |
| 1.100e-03 | -6.81 | Citrate cycle (TCA cycle, Krebs cycle) | KEGG pathways | M00009 | 22 | 10 | 7161 | 1149 |
SDHB,SUCLG1,MDH2,IDH3A,CS,SUCLG2,MDH1,OGDH,IDH3B,SDHA |
| 1.100e-03 | -6.81 | RWD | smart domains | SM00591 | 10 | 6 | 9493 | 1367 |
EIF2AK4,RWDD1,RNF14,WDR59,RNF25,RWDD4 |
| 1.103e-03 | -6.81 | MODULE_36 | MSigDB lists | MODULE_36 | 148 | 37 | 17377 | 2626 |
MBD1,CDS2,PLXNC1,TRIP12,ADAM10,TRAK1,RRM1,PLAGL2,SLC25A12,CREBL2,SNRPD3,KRR1,FLAD1,PCNA,KLHL20,LPIN2,DAPK1,CDKN1B,UPF2,SLC26A2,SCYL3,NCOA2,ZNF189,AGGF1,GALC,E2F3,SYMPK,TTLL4,ACOX1,PARG,CTBS,ANP32E,FKBP5,SRSF3,ATP6V1C1,ADNP2,RNF114 |
| 1.104e-03 | -6.81 | GSE18791_UNSTIM_VS_NEWCATSLE_VIRUS_DC_6H_UP | MSigDB lists | GSE18791_UNSTIM_VS_NEWCATSLE_VIRUS_DC_6H_UP | 179 | 43 | 17377 | 2626 |
TRERF1,UBN1,IVNS1ABP,PHF23,URB2,GADD45G,IRF3,SLC35B1,IKBIP,BRIX1,SLC20A1,RPAIN,HMG20A,JMY,RRN3,ZNF420,MED8,SUV39H2,PPP1R8,MSH2,PREB,SAP30,PHF20L1,TMEM115,DDX24,NSDHL,FRAT2,DDX20,SLBP,WDR82,DCUN1D5,PCGF1,HAUS8,EIF3K,ZNF317,SERTAD2,EIF4ENIF1,KBTBD7,MRFAP1L1,TRIM32,ZBTB11,ADNP2,ZBTB24 |
| 1.104e-03 | -6.81 | GSE17721_CTRL_VS_PAM3CSK4_2H_BMDC_UP | MSigDB lists | GSE17721_CTRL_VS_PAM3CSK4_2H_BMDC_UP | 179 | 43 | 17377 | 2626 |
MANBA,TOR3A,GNE,DCTN2,TAP1,DHX8,NUF2,C14orf119,RFWD3,UCHL5,DUT,TBC1D14,SOCS6,TIMELESS,FAM76B,UBE3B,CYB5R1,RPAP3,ZFP64,SNX2,PBXIP1,BAZ2A,VHL,NARF,PCGF6,MRPL43,DIDO1,ZP3,PSMB9,MYO1F,HHEX,FNTA,ACOX1,ERGIC3,ACAT1,YWHAZ,CNOT6,TMEM101,NCOA1,NANP,TAF6,ZMAT3,SLC25A39 |
| 1.104e-03 | -6.81 | GSE19401_PAM2CSK4_VS_RETINOIC_ACID_STIM_FOLLICULAR_DC_UP | MSigDB lists | GSE19401_PAM2CSK4_VS_RETINOIC_ACID_STIM_FOLLICULAR_DC_UP | 179 | 43 | 17377 | 2626 |
MPHOSPH8,RRP15,TMEM41B,SUMO2,YTHDC2,KIF23,RACGAP1,GMCL1,SECISBP2,ARGLU1,IRF3,IL21R,FBXO22,CFLAR,PAPOLA,PCNA,XRCC2,RAD23B,SLC44A1,MINPP1,MYBL1,IMPA2,ABCC5,ZDHHC18,TRIM8,TRAFD1,FAM49B,KIF15,WIPF1,MTMR6,ARMC8,PICALM,EPB41,MTHFD2,OSBPL11,LUC7L3,CCDC69,ST3GAL2,HMGB2,NDE1,PDLIM5,CCDC59,LRP8 |
| 1.104e-03 | -6.81 | GO_CELLULAR_RESPONSE_TO_OXIDATIVE_STRESS | MSigDB lists | GO_CELLULAR_RESPONSE_TO_OXIDATIVE_STRESS | 179 | 43 | 17377 | 2626 |
NQO1,PRKAA1,SIRT2,ETS1,FOXO3,PARK7,PDK2,MDM2,PDCD10,CCNA2,ATP2A2,DNM2,AKR1B1,BCL2,HTRA2,PTPRK,PPIF,TXNL1,STAU1,TNFAIP3,NET1,OXR1,PRKRA,KLF6,MTR,PRDX1,RHOB,HSPA1B,FAS,ALDH3B1,PRDX3,STAT6,ARNTL,PRDX5,MPV17,PML,PKD2,MAP3K5,PPP5C,CDK2,CPEB2,HDAC2,ADNP2 |
| 1.104e-03 | -6.81 | SMARCA5 (SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5) | protein interactions | 8467 | 129 | 35 | 17029 | 2761 |
COX15,MAX,FOXM1,SUZ12,CDT1,LMNA,RPA2,USF1,SMC3,EIF4A3,MSH2,CREB1,DNMT1,HNRNPM,CDC5L,BAZ2A,PRKDC,NFATC2,BRCA1,SEPT7,MBD3,XRCC5,RPA1,UBTF,CHD3,HNRNPR,BAZ1B,RUVBL2,RBPJ,BEND3,RBBP4,H3F3A,CDK2,HDAC2,IFI16 |
| 1.106e-03 | -6.81 | GO_ANCHORING_JUNCTION | MSigDB lists | GO_ANCHORING_JUNCTION | 471 | 96 | 17377 | 2626 |
RHOG,PDCD6IP,ADD1,RPLP2,ADAM10,ACTR3,RAC1,MYH9,ZFYVE21,LYN,GNB2,GIT2,CPNE3,DST,DLG5,RAB21,CDC42,SYNM,DNM2,KIF22,SENP1,PCBP2,CFL1,PTPRK,AATF,LAP3,RPL38,EZR,CADM1,STX16,RPS9,AHNAK,JAK1,LIMK1,RPS14,CORO1C,ITGB1,RPLP1,ADAM9,ATP6V0C,ACTB,MAPK1,CAPN1,NUMB,PPIB,RPS15,RPS2,PKP4,PPP1R12A,ANXA6,FLOT1,LAMTOR3,B4GALT1,KIF23,SLC4A2,NCKAP1,ARF1,ITGB5,PIP5K1C,CAPN2,CD59,FGFR3,TNS3,VASP,ARPC5,ANXA5,ARHGEF2,ATP6V0A2,RPL19,CNN2,PABPC1,PDLIM2,PDPK1,CYFIP1,PPP1R9B,ADAM17,DCAF6,RHOA,CSRP1,RPS10,RPL6,RPL8,KRAS,PLEC,MAP2K2,RHOB,HSPA1B,MAPK3,CAT,SCARB2,GNA12,KEAP1,PDLIM1,SNAP23,YWHAZ,CD81 |
| 1.107e-03 | -6.81 | GO_ATPASE_ACTIVATOR_ACTIVITY | MSigDB lists | GO_ATPASE_ACTIVATOR_ACTIVITY | 16 | 8 | 17377 | 2626 |
DNAJC10,DNAJC2,AHSA1,TOR1AIP1,RAB4A,DNAJC24,TOR1AIP2,DNAJB1 |
| 1.107e-03 | -6.81 | GO_REGULATION_OF_GENE_EXPRESSION_BY_GENETIC_IMPRINTING | MSigDB lists | GO_REGULATION_OF_GENE_EXPRESSION_BY_GENETIC_IMPRINTING | 16 | 8 | 17377 | 2626 |
PRMT7,CTCF,BRCA1,DNMT3A,KCNQ1,KDM1B,MECP2,ARID4A |
| 1.107e-03 | -6.81 | GO_RECEPTOR_CATABOLIC_PROCESS | MSigDB lists | GO_RECEPTOR_CATABOLIC_PROCESS | 16 | 8 | 17377 | 2626 |
CDK5,TGFB1,SNX25,ZNRF3,BECN1,SMURF1,SH3GLB1,CAPN1 |
| 1.107e-03 | -6.81 | GO_LYSINE_ACETYLATED_HISTONE_BINDING | MSigDB lists | GO_LYSINE_ACETYLATED_HISTONE_BINDING | 16 | 8 | 17377 | 2626 |
BRD4,BRD2,BAZ2A,BAZ1B,SMARCA4,BRD7,BRD9,CARM1 |
| 1.107e-03 | -6.81 | MOOTHA_TCA | MSigDB lists | MOOTHA_TCA | 16 | 8 | 17377 | 2626 |
SDHB,SUCLG1,MDH2,IDH3A,CS,OGDH,IDH3B,SDHA |
| 1.107e-03 | -6.81 | HIPK4 (homeodomain interacting protein kinase 4) | protein interactions | 147746 | 29 | 12 | 17029 | 2761 |
ATP1A1,NUP188,RAF1,ACSL3,AKAP8,SUGP2,TECR,RBBP4,LPCAT1,PFKP,CDKN2A,ZNF146 |
| 1.107e-03 | -6.81 | YY1AP1 (YY1 associated protein 1) | protein interactions | 55249 | 29 | 12 | 17029 | 2761 |
ZNF524,ZNF496,MDM2,CDC16,EWSR1,VHL,ATXN1,FBL,MAPK14,SMURF1,LUC7L,MAD2L2 |
| 1.107e-03 | -6.81 | Prkci (protein kinase C, iota) | protein interactions | 18759 | 29 | 12 | 17029 | 2761 |
KEAP1,TIMM23,NOL8,DNM2,MRPL11,TMEM165,NIPSNAP2,LSG1,PARD3,NIPSNAP1,TMEM160,MBD4 |
| 1.107e-03 | -6.81 | NR2C1 (nuclear receptor subfamily 2 group C member 1) | protein interactions | 7181 | 29 | 12 | 17029 | 2761 |
PSPC1,MTA1,MTA2,PML,SMARCA4,RCOR1,RBBP4,MBD3,DNMT1,TRIM28,NUDT3,HDAC2 |
| 1.114e-03 | -6.80 | ID2 (inhibitor of DNA binding 2) | protein interactions | 3398 | 83 | 25 | 17029 | 2761 |
TCF12,ADD1,TSTA3,VHL,TCF3,ELP4,DIDO1,ELK1,HDGFL2,MACF1,SLTM,MAPK3,AFDN,RB1,C1orf131,KLHL20,SUV39H2,RBL1,E2F4,STK38,YY1,CDK2,MAPK1,IFI16,TUBB |
| 1.117e-03 | -6.80 | COPS4 (COP9 signalosome subunit 4) | protein interactions | 51138 | 92 | 27 | 17029 | 2761 |
COPS8,FGFR1OP,RBX1,DCAF8,CAST,CUL3,KLHL18,CUL1,CSNK2A1,TOR1AIP2,KRAS,BTBD1,LRRC14,DTL,MBIP,DDA1,FBXO7,DCAF11,FEM1B,STK11,COPS7B,KPNA2,KLHL42,COPS6,UBE2M,DDB1,SNAPIN |
| 1.117e-03 | -6.80 | COPS3 (COP9 signalosome subunit 3) | protein interactions | 8533 | 92 | 27 | 17029 | 2761 |
COPS8,UNK,EWSR1,RBX1,DCAF8,RAF1,CUL3,KLHL18,CUL1,CSNK2A1,TOR1AIP2,PBRM1,BTBD1,LRRC14,DTL,CENPJ,KLHL15,DDA1,FBXO7,DCAF11,FEM1B,STK11,COPS7B,KLHL42,COPS6,MCPH1,DDB1 |
| 1.117e-03 | -6.80 | PKB-mediated events | REACTOME pathways | R-HSA-109703 | 40 | 15 | 10287 | 1696 |
TSC1,PRKAB1,TSC2,AKT2,PRKAA1,LAMTOR4,LAMTOR3,CAB39,RRAGC,STK11,AKT1S1,PDE3B,RHEB,MLST8,EEF2K |
| 1.117e-03 | -6.80 | response to abiotic stimulus | biological process | GO:0009628 | 1108 | 205 | 17256 | 2622 |
TXN,NPHP4,NF1,TSC22D3,TMEM109,ALKBH5,SLC29A1,SIRT2,CCNB1,IKBIP,BECN1,MAPK14,ANKRD23,RBM4,BIRC2,MBD4,EEF2K,CDK5,USF1,PCNA,PSMD1,RCSD1,XRCC2,NOC2L,DNM2,AKR1B1,CRY2,MTPN,OGG1,PTPRK,PLK3,BAK1,ERCC1,DEAF1,RBX1,AKT2,RAD51AP1,VHL,PBK,MRNIP,LRP5,AURKB,BRCA1,MAP3K4,RAD18,RPS27A,PSMD8,ITGB1,CAB39,STK11,CHEK2,PIEZO1,FBXL3,ARRB2,PSMC1,HDAC2,B4GALT2,UBE2D3,HSPH1,PHB2,AGTRAP,TM9SF4,PRKAA1,RRM1,EIF2AK4,PSMD9,METTL3,RHBDD1,LMNA,CFLAR,DTL,TIGAR,INTS7,MBD2,XPA,MSH2,TIMELESS,ATP6V0A2,BCL2,AHCY,SLC12A2,ATP6V0D1,EEF1D,HP1BP3,CYFIP1,ERO1A,GBA,PSMA1,KRAS,MAP4K3,UBE4B,ADRB2,PKM,ELK1,RHOB,PSMB3,PSMC4,FAS,RDH11,XRCC5,ADSS,CAT,MBIP,TSC1,PDLIM1,NSMF,RUVBL2,YY1,EGLN1,KARS,ATXN3,DNMT3A,NQO1,RAB11B,RAF1,RAC1,SLC2A1,BCL2L1,PRKACA,LYN,APP,BABAM2,MDM2,PSMA6,CCNA2,STRBP,MTA1,NABP1,CLCN6,CDKN1B,ATF2,SPIDR,HTRA2,CHP1,ATP6V1G1,PSMA8,BTG2,POLR2D,PSMB7,CIRBP,LRRC8A,DCLRE1C,DNAJA1,TANC1,PSMB9,RAD51C,HSPA4,ATP1A1,SCAP,PSMD3,HIPK2,H2AFX,STAT1,XRCC3,TRIM32,XRCC4,USP53,SMAD4,RAD51D,EYA1,MECP2,BABAM1,HABP4,BLM,ETS1,FOXO3,RFWD3,CAPN2,PSMD2,CTSS,SUV39H2,PTEN,TANK,NABP2,ARHGEF2,CNN2,MAP3K14,CREB1,CITED2,GTF2H2,MSH6,TGFB1,PDPK1,HMGN1,ADAM17,RHOA,POLK,NET1,PRKDC,LDHA,ADSL,MEN1,FADD,HSPA1B,MAPK3,PDCD6,E2F1,PML,AEN,PKD2,RBPJ,CPEB2,HRAS,IFI16,DDB1 |
| 1.120e-03 | -6.79 | Warburg Effect | SMPDB pathways | SMP00654 | 44 | 16 | 992 | 167 |
SUCLG1,IDH3A,TKT,GLUD1,OGDH,PKM,SDHA,MPC1,SDHB,CS,SUCLG2,SLC16A1,MDH1,GPI,TALDO1,IDH3B |
| 1.120e-03 | -6.79 | HTLV-I infection | KEGG pathways | hsa05166 | 256 | 60 | 7161 | 1149 |
HLA-E,TCF3,SLC2A1,PTTG1,XIAP,PPP3CB,BCL2L1,ETS1,PRKACA,HLA-A,FZD6,CREM,CDKN2C,RB1,NFATC3,PCNA,PIK3R2,ADCY9,ANAPC7,CREB1,MAP3K14,MYBL1,ATF2,DVL2,ADCY7,TGFB1,PPP3CA,NRAS,KAT2A,AKT2,E2F3,VDAC2,MYBL2,ANAPC2,NFATC2,KRAS,CDC23,ELK1,VDAC1,SLC25A5,HLA-B,SMAD2,CDC16,JAK1,CDC27,POLE,ETS2,GPS2,WNT5B,PPP3R1,TBPL1,E2F1,DVL1,CHEK2,CCNB2,E2F2,SMAD4,HRAS,ANAPC4,CDKN2A |
| 1.120e-03 | -6.79 | HTLV-I infection | KEGG pathways | ko05166 | 256 | 60 | 7161 | 1149 |
HLA-E,TCF3,SLC2A1,PTTG1,XIAP,PPP3CB,BCL2L1,ETS1,PRKACA,HLA-A,FZD6,CREM,CDKN2C,RB1,NFATC3,PCNA,PIK3R2,ADCY9,ANAPC7,CREB1,MAP3K14,MYBL1,ATF2,DVL2,ADCY7,TGFB1,PPP3CA,NRAS,KAT2A,AKT2,E2F3,VDAC2,MYBL2,ANAPC2,NFATC2,KRAS,CDC23,ELK1,VDAC1,SLC25A5,HLA-B,SMAD2,CDC16,JAK1,CDC27,POLE,ETS2,GPS2,WNT5B,PPP3R1,TBPL1,E2F1,DVL1,CHEK2,CCNB2,E2F2,SMAD4,HRAS,ANAPC4,CDKN2A |
| 1.123e-03 | -6.79 | GO_MATURATION_OF_SSU_RRNA | MSigDB lists | GO_MATURATION_OF_SSU_RRNA | 39 | 14 | 17377 | 2626 |
UTP20,NOL11,UTP18,LSM6,TBL3,RPS14,RPS24,UTP3,RRS1,TSR2,BYSL,RPSA,RRP36,KRR1 |
| 1.123e-03 | -6.79 | FLECHNER_PBL_KIDNEY_TRANSPLANT_OK_VS_DONOR_DN | MSigDB lists | FLECHNER_PBL_KIDNEY_TRANSPLANT_OK_VS_DONOR_DN | 39 | 14 | 17377 | 2626 |
USP7,MKNK1,EID1,GADD45B,ANXA5,BCLAF1,DDX5,ANP32E,LYN,MAPK14,RAB11A,MYL12B,RHEB,ATP6V1G1 |
| 1.123e-03 | -6.79 | PID_ATR_PATHWAY | MSigDB lists | PID_ATR_PATHWAY | 39 | 14 | 17377 | 2626 |
PLK1,RPA2,PPP2CA,RFC3,MDM2,CCNA2,CLSPN,TIMELESS,CDC6,YWHAZ,MCM2,CDK2,RFC2,RPA1 |
| 1.123e-03 | -6.79 | GCM_SIRT2 | MSigDB lists | GCM_SIRT2 | 39 | 14 | 17377 | 2626 |
UBL3,KIF3B,SNX27,GOLGA7,GORASP1,IL6ST,MAP4K4,GLTP,SIRT2,LANCL1,ZNF710,MYO9A,DYNC1LI2,MFN2 |
| 1.123e-03 | -6.79 | GO_NUCLEOTIDE_EXCISION_REPAIR_DNA_INCISION | MSigDB lists | GO_NUCLEOTIDE_EXCISION_REPAIR_DNA_INCISION | 39 | 14 | 17377 | 2626 |
RPA2,ERCC1,PCNA,RFC3,RBX1,POLK,RPS27A,CHD1L,XPA,RFC2,GTF2H2,OGG1,DDB1,RPA1 |
| 1.123e-03 | -6.79 | GO_AUTOPHAGOSOME_ORGANIZATION | MSigDB lists | GO_AUTOPHAGOSOME_ORGANIZATION | 39 | 14 | 17377 | 2626 |
ATG9A,RB1CC1,ATG3,RAB23,ATG13,ATG2B,WIPI2,RAB1A,MAP1LC3B,PSEN1,BECN1,PACS2,ATG4A,MFN2 |
| 1.123e-03 | -6.79 | Neutrophil degranulation | REACTOME pathways | R-HSA-6798695 | 487 | 106 | 10287 | 1696 |
ADA2,RHOG,RAB14,ADAM10,DYNLL1,RAC1,HEXB,NIT2,NHLRC3,GYG1,MAPK14,KCMF1,CMTM6,CPNE3,PA2G4,RAP1A,PSMD1,AP1M1,BRI3,TMBIM1,GM2A,KCNAB2,CPNE1,ENPP4,CCT2,TIMP2,NRAS,ARHGAP45,RAB7A,PPIE,PSMB7,CYSTM1,ATP6V0A1,TOLLIP,RAB5B,ALDH3B1,DDOST,DSN1,AGPAT2,SURF4,RAB24,PSMD3,CAB39,CANT1,ATP6V0C,ROCK1,PDXK,LTA4H,MAPK1,CAPN1,TUBB,SVIP,MIF,DNAJC5,GMFG,MANBA,PDAP1,LAMTOR3,B4GALT1,ASAH1,CDK13,MAN2B1,RAB6A,PSEN1,HLA-A,TMEM179B,GNS,CD59,PSMD2,CTSS,ARPC5,HUWE1,OSTF1,CNN2,MVP,LPCAT1,SPTAN1,CYFIP1,FTL,RHOA,MLEC,CREG1,C1orf35,HEBP2,PKM,ARMC8,CCT8,NEU1,HSPA1B,XRCC5,CAND1,CAT,HLA-B,RAB18,ATP6V1D,GOLGA7,MAGT1,SNAP29,SNAP23,ACLY,PGRMC1,IMPDH1,CTSA,GPI,PSAP,PGAM1 |
| 1.129e-03 | -6.79 | NAKAMURA_TUMOR_ZONE_PERIPHERAL_VS_CENTRAL_DN | MSigDB lists | NAKAMURA_TUMOR_ZONE_PERIPHERAL_VS_CENTRAL_DN | 569 | 113 | 17377 | 2626 |
WASF2,ZNF207,ZNF496,TOMM20,UGP2,AGRN,CAST,ANK3,XIAP,ENSA,CCNL2,IKBIP,SNN,SEC16A,RCOR3,PABPC4,SSR1,C2orf68,HNRNPA2B1,CYHR1,SHC1,RAB4A,TTC3,ZNF226,MAVS,SPTSSA,ANKRD9,ABI1,DRAM2,USP34,RYBP,USO1,RHOBTB3,ERMP1,BIRC3,NCK1,AZI2,KRTCAP2,BTBD1,RPL37,WDR11,RAB24,STAT6,GOLGA8A,CHMP4B,FBXL3,SLC22A23,LTA4H,LONP2,CBX4,CAPN1,PDCD4,CSNK1D,UBE2D3,DNAJC5,HLA-E,B4GALT5,SRSF6,SRGN,TIA1,RPL15,LETMD1,KLF13,NCKAP1,DNAJB1,RAB11A,ARID1B,SLC25A36,FKBP1A,FGFR3,ADD3,GART,C4orf3,ITGB8,PTEN,CITED2,RNF135,EIF3L,ADAM17,ANKRD37,GALC,TIMMDC1,CREG1,RB1CC1,DENND4C,FBXO9,NFATC2IP,PNPLA8,SRSF5,MACF1,KDM3A,RBM38,DTWD1,SEC31A,CAT,HLA-B,SLCO4A1,SERTAD2,FNTA,ETS2,ACOX1,NFIL3,SAMD8,ZRANB2,RBPJ,YY1,PPP6R2,ZMIZ1,IGBP1,N4BP2L2,ESYT2,RNF114,EGLN1 |
| 1.131e-03 | -6.78 | RNA Polymerase I Transcription Initiation | REACTOME pathways | R-HSA-73762 | 48 | 17 | 10287 | 1696 |
POLR2L,KAT2A,POLR2K,MTA2,MBD3,TTF1,TWISTNB,UBTF,RRN3,CD3EAP,CHD3,MTA1,POLR1B,RBBP4,ZNRD1,GTF2H2,HDAC2 |
| 1.132e-03 | -6.78 | EDC4 (enhancer of mRNA decapping 4) | protein interactions | 23644 | 57 | 19 | 17029 | 2761 |
YTHDC1,KIF11,ABCF1,GIT2,PIP4K2A,FKBP3,EDC3,RPA1,CRKL,RPA2,MDM2,UPF1,C4orf3,DCP1A,GTSE1,DDX5,SGF29,IFI16,CDC5L |
| 1.132e-03 | -6.78 | LUC7L3 (LUC7 like 3 pre-mRNA splicing factor) | protein interactions | 51747 | 57 | 19 | 17029 | 2761 |
UNK,SART1,SUZ12,PTTG1,RNPS1,SMU1,CUL1,JMJD6,LUC7L,LMNA,SRSF1,CAND1,LUC7L3,BANF1,UHRF2,NABP2,ZRANB2,LUC7L2,SRPK2 |
| 1.132e-03 | -6.78 | POLR2L (RNA polymerase II subunit L) | protein interactions | 5441 | 57 | 19 | 17029 | 2761 |
POLR2I,POLR2G,ELOA,POLR2D,POLR3GL,PSMB9,SPAG5,POLR2A,PHC2,MED10,L3MBTL3,RPAP1,TP53BP2,POLR1B,CHEK2,COIL,RPRD1B,ASB6,SMARCD1 |
| 1.132e-03 | -6.78 | DYNC1I2 (dynein cytoplasmic 1 intermediate chain 2) | protein interactions | 1781 | 57 | 19 | 17029 | 2761 |
MAPRE1,ADD1,DYNLL1,CUL3,BRCA1,KDM1B,ABCF1,EIF3G,EIF3A,MAPK3,XRCC5,EIF3K,ADD3,PSMD8,YBX1,RPS26,DYNC1LI2,CCAR1,DCTN1 |
| 1.132e-03 | -6.78 | GSE10325_LUPUS_BCELL_VS_LUPUS_MYELOID_UP | MSigDB lists | GSE10325_LUPUS_BCELL_VS_LUPUS_MYELOID_UP | 174 | 42 | 17377 | 2626 |
SUZ12,TCF3,MAGED1,GSPT2,CUTA,ZNF107,SMC6,NKRF,NIT2,GTF3A,PPP1R16B,ANKRD28,IRF4,NOL11,IARS,ATIC,AKR1B1,CDC25B,TCEA1,ALDH18A1,FBL,RBM15,HTRA2,LDHB,POU2AF1,HMGN1,RPL35,GNG7,LRBA,DNAJC9,ITM2A,ODC1,RPSA,PDLIM1,HINT1,ACYP1,GOLGA8A,FAM3C,QRSL1,TRAF5,TMEM14A,NGLY1 |
| 1.132e-03 | -6.78 | GSE27786_LSK_VS_MONO_MAC_UP | MSigDB lists | GSE27786_LSK_VS_MONO_MAC_UP | 174 | 42 | 17377 | 2626 |
SLC29A1,OAT,POLR3K,RPAIN,QSOX2,HMG20A,MYEF2,APOPT1,ATPAF1,EDC3,SNRNP25,ZBTB45,FBXL6,HUWE1,IMPAD1,BANF1,PHF14,ZDHHC13,KIFAP3,SGCB,C12orf75,RPL22L1,STRAP,MED22,CDC5L,TSHZ1,NTPCR,CCT2,PRKDC,SSR2,NUP155,CDC23,GUF1,C1orf122,XRCC5,CCDC86,EXOC4,PKD2,RUVBL2,MAPK1,MZT2B,RPS26 |
| 1.132e-03 | -6.78 | GSE11864_CSF1_VS_CSF1_IFNG_PAM3CYS_IN_MAC_DN | MSigDB lists | GSE11864_CSF1_VS_CSF1_IFNG_PAM3CYS_IN_MAC_DN | 174 | 42 | 17377 | 2626 |
HIVEP3,URB2,SECISBP2,NANS,LYN,TMEM165,RAB21,SLC1A4,ZNRF2,ATG3,BUD31,AXIN2,RPF2,JOSD1,FBXL19,RHBDD2,ACSL5,ADAM17,EXOSC6,KIAA0040,SUGP2,TEX10,EDF1,PITPNB,ICAM2,EIF4H,EML4,TRIM26,MFAP1,GADD45B,WDR4,DBI,MRPL27,TBPL1,CEBPG,PTPN7,PPP1R11,DUSP11,SAMD8,TUBB,STARD3NL,NXT2 |
| 1.132e-03 | -6.78 | GSE36095_WT_VS_HDAC9_KO_TREG_UP | MSigDB lists | GSE36095_WT_VS_HDAC9_KO_TREG_UP | 174 | 42 | 17377 | 2626 |
PRKCSH,VAV2,CERK,TIA1,KIF23,HMGN3,NUF2,NIT2,HAUS4,CDC42SE2,MXD4,BZW2,RFWD3,PA2G4,USF1,TNFAIP8,BANF1,PRC1,IMPA2,S100A6,PREB,PGAP2,CLPTM1,PLK1,TDP1,CYFIP1,TNFAIP3,ELL2,ASPM,LDHA,USP10,KIF11,ASF1B,IRF5,RHOB,ALKBH6,MASTL,CEP55,FAM126A,H3F3A,EYA2,AAAS |
| 1.135e-03 | -6.78 | Transport of Mature mRNA Derived from an Intronless Transcript | REACTOME pathways | R-HSA-159231 | 44 | 16 | 10287 | 1696 |
NDC1,NUP188,RAE1,NUP54,NUP155,SYMPK,NUP205,NUP210,NUP107,NUP153,NUP62,CPSF4,NUP58,NUP85,SEH1L,AAAS |
| 1.138e-03 | -6.78 | PID_P53_DOWNSTREAM_PATHWAY | MSigDB lists | PID_P53_DOWNSTREAM_PATHWAY | 133 | 34 | 17377 | 2626 |
PRKAB1,TSC2,CASP6,TAP1,PMS2,SMARCA4,BCL2L1,CCNB1,JMY,CCNK,RB1,MDM2,PCNA,PTEN,MSH2,BCL2,TP53BP2,CARM1,BAK1,PLK3,KAT2A,BTG2,MAP4K4,E2F3,MCL1,IRF5,FAS,DGCR8,TFDP1,E2F1,PML,DDX5,E2F2,HDAC2 |
| 1.138e-03 | -6.78 | GSE39556_CD8A_DC_VS_NK_CELL_UP | MSigDB lists | GSE39556_CD8A_DC_VS_NK_CELL_UP | 195 | 46 | 17377 | 2626 |
TMEM106C,TXN,FOXM1,CENPF,HEXB,C5orf30,SLC25A12,KIF23,KIF2C,AP3S1,FOXO3,EBP,PRNP,DST,FANCL,SLC31A1,GART,CCNA2,IARS,ATIC,DUT,MDFIC,TRIM14,GINS1,CYFIP1,TK1,SIGMAR1,PPT1,NET1,MAP4K4,LDHA,PSMG1,KIF11,MACF1,PRPSAP1,HSPB11,MTHFD2,POLE,STT3A,CERS6,PGRMC1,H2AFX,IMPDH1,RGL1,ARRB2,UBE2C |
| 1.138e-03 | -6.78 | GSE17721_LPS_VS_POLYIC_4H_BMDC_UP | MSigDB lists | GSE17721_LPS_VS_POLYIC_4H_BMDC_UP | 195 | 46 | 17377 | 2626 |
WSB2,UBE2E2,MAGEH1,TM9SF4,SNRPD3,CDC73,FARSA,VASP,SAR1A,RALB,SLC44A1,PTPN11,HADHB,CS,INTS12,PIKFYVE,SGCB,LRRC59,UBE2M,SEH1L,SAP30,RBM15B,ACSL5,PPIF,TXNL1,TSHZ1,TMEM115,HMGN5,SMU1,TUFM,AZI2,ISG15,HSPA1B,PSMC4,CDC27,SURF4,ETS2,CCDC86,ACYP1,ZNF689,GADD45B,ACLY,ITGB1,LY75,CBX4,PDCD4 |
| 1.138e-03 | -6.78 | GSE21670_STAT3_KO_VS_WT_CD4_TCELL_TGFB_TREATED_UP | MSigDB lists | GSE21670_STAT3_KO_VS_WT_CD4_TCELL_TGFB_TREATED_UP | 195 | 46 | 17377 | 2626 |
HIVEP3,MMACHC,ZNF496,LZTR1,MCM10,LUZP1,TMEM41B,FAM76A,PLAGL2,C2orf49,PITHD1,KCMF1,QSOX2,PRNP,CDKN2C,COQ4,NVL,TBC1D22A,XRCC2,MECR,KNTC1,GEMIN4,F2R,N4BP2,TMBIM1,FDFT1,LARS,CELSR2,ZNF202,E2F3,CKAP2L,ELP4,CDC6,EIF4H,ODC1,BBS12,RAB2B,RAD54B,HAUS8,IDE,MTHFD2,OSBPL11,WDR11,POLE,AEN,RBPJ |
| 1.142e-03 | -6.77 | GNF2_PAK2 | MSigDB lists | GNF2_PAK2 | 27 | 11 | 17377 | 2626 |
VAV1,WAS,GMFG,ARPC5,ADAM10,OSBPL8,STAT6,RAF1,ACTR3,CAPZA1,ARHGDIB |
| 1.142e-03 | -6.77 | REACTOME_SIGNALLING_TO_RAS | MSigDB lists | REACTOME_SIGNALLING_TO_RAS | 27 | 11 | 17377 | 2626 |
NRAS,SHC1,RALB,MAPKAPK3,RAF1,KRAS,MAPK14,MAPK1,HRAS,MAP2K2,MAPK3 |
| 1.142e-03 | -6.77 | GO_PROTON_TRANSPORTING_TWO_SECTOR_ATPASE_COMPLEX | MSigDB lists | GO_PROTON_TRANSPORTING_TWO_SECTOR_ATPASE_COMPLEX | 27 | 11 | 17377 | 2626 |
PPIF,ATP6V0B,ATP6V1D,ATP6V0A1,ATP6V0A2,ATP6V0C,ATP6V1B2,ATP6V1C1,ATP6V0D1,ATP6V0E1,ATP6V1G1 |
| 1.142e-03 | -6.77 | TERAO_AOX4_TARGETS_HG_UP | MSigDB lists | TERAO_AOX4_TARGETS_HG_UP | 27 | 11 | 17377 | 2626 |
GNS,SNX27,GNA12,CYTH1,TMEM127,PEX5,NSF,RAF1,KIAA0930,UBE2V1,NAA60 |
| 1.145e-03 | -6.77 | CHUNG_BLISTER_CYTOTOXICITY_UP | MSigDB lists | CHUNG_BLISTER_CYTOTOXICITY_UP | 123 | 32 | 17377 | 2626 |
TCF12,MIF4GD,MRPL9,RACGAP1,NANS,SLC35B2,GGA2,HCFC1R1,PAIP1,FANCL,PSMD2,SLC1A4,TIMM23,MCM5,GMEB1,CISD2,CHTOP,SYTL3,N4BP2,COPS8,TNFAIP3,BORA,CYB5A,SUPT16H,CHCHD3,GALNT2,COX5A,USP11,EHD4,CD81,CHID1,PSMC1 |
| 1.147e-03 | -6.77 | SORT1 (sortilin 1) | protein interactions | 6272 | 134 | 36 | 17029 | 2761 |
COPA,NOP2,GGA1,ZNF768,URB2,XIAP,MED13L,KLC1,IRF3,GGA2,BRIX1,STAM,SSR1,WWP2,PHC2,XRCC2,YBX1,ICE2,FBXL19,TMEM9,CSNK1G2,UTP15,LEMD2,MAP3K4,UPF1,MRPL55,UAP1,SYNCRIP,NSMCE2,USP32,TCOF1,USP11,CDK2,C2CD5,TUBB,ZC3HAV1 |
| 1.147e-03 | -6.77 | SF1 (splicing factor 1) | protein interactions | 7536 | 134 | 36 | 17029 | 2761 |
NCOR2,HSPH1,EWSR1,SUZ12,TKT,XPO7,RBM4,LMNA,WWP2,RBM17,GART,CDC42,EFTUD2,SEPT11,BCL2,CNN2,HNRNPF,CUL3,ILF3,CIRBP,ATXN1,TOMM40,VDAC1,METTL22,PRMT2,SF3A2,ZFR,DDX17,XRCC5,HSPBP1,PLAA,PML,CAB39,NCOA1,FUS,FAF1 |
| 1.157e-03 | -6.76 | Association of licensing factors with the pre-replicative complex | REACTOME pathways | R-HSA-69298 | 15 | 8 | 10287 | 1696 |
CDC6,ORC1,ORC3,E2F2,RPS27A,CDT1,E2F1,E2F3 |
| 1.159e-03 | -6.76 | GO_INTRINSIC_APOPTOTIC_SIGNALING_PATHWAY_IN_RESPONSE_TO_DNA_DAMAGE | MSigDB lists | GO_INTRINSIC_APOPTOTIC_SIGNALING_PATHWAY_IN_RESPONSE_TO_DNA_DAMAGE | 70 | 21 | 17377 | 2626 |
BAK1,PGAP2,PRKDC,TMEM109,MCL1,TOPORS,BRCA1,BCL2L1,MOAP1,HIPK2,XPA,PML,MSH2,E2F1,AEN,BCL2,FNIP2,CHEK2,HTRA2,IFI16,MSH6 |
| 1.159e-03 | -6.76 | GCM_DLG1 | MSigDB lists | GCM_DLG1 | 70 | 21 | 17377 | 2626 |
GORASP1,KLHL21,MAP4K4,FBXO9,ATG2B,LANCL1,ZER1,MOAP1,NAPG,GOLGA7,MTMR4,IL6ST,SH3GLB2,GLTP,SLAIN1,CLDND1,PREPL,ZNF710,SAP30L,NIPA1,CAMK2G |
| 1.160e-03 | -6.76 | GSE11864_CSF1_PAM3CYS_VS_CSF1_IFNG_PAM3CYS_IN_MAC_UP | MSigDB lists | GSE11864_CSF1_PAM3CYS_VS_CSF1_IFNG_PAM3CYS_IN_MAC_UP | 169 | 41 | 17377 | 2626 |
BCCIP,LYRM4,SRGN,EIF3D,SDC2,OLA1,HCFC1R1,QSOX2,RBM17,ANKRD26,LYAR,CAPN2,PA2G4,NEK6,IARS,SLC44A1,RAD23B,NOC2L,HADHB,MRPL32,IMPA2,PLK1,B3GALT6,LARS,UBQLN4,SEPT9,HNRNPF,LDHA,ITM2A,GAR1,ZNF174,ZFR,TRIM47,GADD45B,LRPPRC,PGRMC1,TATDN1,ZNF146,TUBB,DDX42,SSRP1 |
| 1.162e-03 | -6.76 | ATM Signaling Network in Development and Disease | WikiPathways | WP3878 | 46 | 16 | 5312 | 837 |
CDK5,HMGN1,TSC2,PRKDC,PRKAA1,H2AFX,STK11,DCLRE1C,CHEK2,AURKB,CEP63,MAP3K5,PPP5C,ATF2,TRIM28,ATMIN |
| 1.164e-03 | -6.76 | REACTOME_G1_PHASE | MSigDB lists | REACTOME_G1_PHASE | 35 | 13 | 17377 | 2626 |
PPP2CA,CDKN2C,RB1,RBL1,RPS27A,E2F4,TFDP1,E2F1,E2F3,CDKN1B,CUL1,E2F2,CDKN2A |
| 1.164e-03 | -6.76 | REACTOME_FORMATION_OF_RNA_POL_II_ELONGATION_COMPLEX_ | MSigDB lists | REACTOME_FORMATION_OF_RNA_POL_II_ELONGATION_COMPLEX_ | 35 | 13 | 17377 | 2626 |
CTDP1,POLR2I,POLR2G,POLR2L,POLR2J,POLR2K,POLR2D,TCEA1,GTF2H2,POLR2A,SSRP1,SUPT16H,GTF2F1 |
| 1.164e-03 | -6.76 | PID_PI3KCI_AKT_PATHWAY | MSigDB lists | PID_PI3KCI_AKT_PATHWAY | 35 | 13 | 17377 | 2626 |
PDPK1,KPNA1,AKT2,PRKDC,RAF1,CDKN1B,YWHAZ,BCL2L1,MAP3K5,YWHAH,PRKACA,FOXO3,MLST8 |
| 1.164e-03 | -6.76 | BIOCARTA_FMLP_PATHWAY | MSigDB lists | BIOCARTA_FMLP_PATHWAY | 35 | 13 | 17377 | 2626 |
CALM2,PPP3CA,NFATC3,RAF1,RAC1,NFATC2,PPP3CB,ELK1,MAPK1,MAPK14,HRAS,MAP2K2,MAPK3 |
| 1.164e-03 | -6.76 | protein stabilization | biological process | GO:0050821 | 163 | 40 | 17256 | 2622 |
ZNF207,USP7,ZBED3,PPIB,PHB2,FLOT1,CREBL2,PARK7,RPL11,NAPG,PDCD10,PTEN,PIN1,GTSE1,PTGES3,CREB1,IFT46,MORC3,CHP1,CDC37,TELO2,CCT2,VHL,GTPBP4,WDR81,OTUD3,SYVN1,PRKRA,SOX4,CCT8,USP36,HSPA1B,TSC1,GOLGA7,SEL1L,NCLN,CHEK2,DVL1,CLU,USP13 |
| 1.164e-03 | -6.76 | purine-containing compound biosynthetic process | biological process | GO:0072522 | 163 | 40 | 17256 | 2622 |
ADA2,GALK1,COX5B,PPCS,SLC35B2,ATP5F1B,ADPGK,ATP5PF,GART,ATIC,ADCY9,PPCDC,ATP6V0A2,SLC26A2,CYC1,ADCY7,AMPD2,TGFB1,GUK1,AMD1,LDHA,ATP6V0A1,ADSL,OGDH,PKM,ATP5MF,STOML2,ADSS,ATP5MC3,DCK,GUCY1B1,PRPS2,IMPDH1,DHTKD1,ACAT1,ATP5F1A,GPI,NIPSNAP2,PGAM1,PFKP |
| 1.167e-03 | -6.75 | ADRM1 (adhesion regulating molecule 1) | protein interactions | 11047 | 70 | 22 | 17029 | 2761 |
TXNL1,PSMB7,PSMA1,BRCA1,UBQLN2,APP,BIRC2,PSMB3,PSMC4,RAD23A,PSMD2,RPN1,PSMA6,PSMD1,HUWE1,UCHL5,PSMD8,PSMD3,RAD23B,RPN2,SMURF1,PSMC1 |
| 1.167e-03 | -6.75 | CACYBP (calcyclin binding protein) | protein interactions | 27101 | 70 | 22 | 17029 | 2761 |
RPAP3,OTUD5,METTL1,NPHP4,CYLD,EWSR1,NFATC2,UBE2I,PRDX1,DERL1,CEP104,SIAH1,SIAH2,FKBP5,TAGLN2,NAA20,PPP6R2,ZRANB1,MAPK1,CARM1,S100A6,USP13 |
| 1.167e-03 | -6.75 | TUBB6 (tubulin beta 6 class V) | protein interactions | 84617 | 70 | 22 | 17029 | 2761 |
CYLD,PTPN18,SUMO2,TUFM,CUL3,BRCA1,CAPZA2,TOMM40,MCM2,PCBP1,EIF3A,SRXN1,SHC1,PIK3R2,CAMKMT,PPP6C,CLU,AHCYL1,CD81,CTDSP2,SSSCA1,HTRA2 |
| 1.167e-03 | -6.75 | XRCC1 (X-ray repair cross complementing 1) | protein interactions | 7515 | 70 | 22 | 17029 | 2761 |
MAX,PPT1,POLK,PRKDC,CHD1L,SF3B6,MRPL12,CSNK2A1,NFATC2,BRCA1,UBE2I,NCAPG,RBM4,RPA1,CAND1,RPA2,PCNA,TIMELESS,SEPT11,CREB1,OGG1,GCC1 |
| 1.167e-03 | -6.75 | ARPC4 (actin related protein 2/3 complex subunit 4) | protein interactions | 10093 | 70 | 22 | 17029 | 2761 |
METTL1,CDKN2AIP,UNK,STAU1,ACTR3,MYH9,CAPZA2,ANLN,MCM2,ARPC1A,SH3GLB1,RPA1,EIF3K,PPP2CA,WAS,UBE2Q2,ARPC5,MYO18A,TTLL12,PDIA6,RPRD1B,FUBP1 |
| 1.168e-03 | -6.75 | methyltransferase activity | molecular function | GO:0008168 | 213 | 50 | 17224 | 2647 |
ASH1L,DNMT3A,NOP2,KMT2E,CXXC1,SUZ12,NSD3,EZH1,WDR5,METTL3,IRF4,KMT5C,SUV39H2,KMT5A,METTL14,CMTR2,PRDM4,FAM86C1,FBL,DNMT1,MRM3,NSUN4,FTSJ3,CARM1,MRM2,METTL1,HEMK1,EHMT1,NSUN2,METTL5,METTL2A,ARMT1,WDR82,EDF1,ICMT,METTL22,KMT2C,PRMT2,MEN1,MTR,PRDM11,DOT1L,SETD3,CAMKMT,WDR4,FTSJ1,KMT2B,PRMT7,TRMT10B,GCSH |
| 1.169e-03 | -6.75 | REACTOME_P53_DEPENDENT_G1_DNA_DAMAGE_RESPONSE | MSigDB lists | REACTOME_P53_DEPENDENT_G1_DNA_DAMAGE_RESPONSE | 52 | 17 | 17377 | 2626 |
PSMA8,PSMB7,PSMA1,PSMB9,PSMD9,PSMB3,PSMC4,PSMD2,PSMA6,PSMD1,MDM2,RPS27A,PSMD3,PSMD8,CDKN1B,CDK2,PSMC1 |
| 1.169e-03 | -6.75 | GALE_APL_WITH_FLT3_MUTATED_UP | MSigDB lists | GALE_APL_WITH_FLT3_MUTATED_UP | 52 | 17 | 17377 | 2626 |
SRSF11,TCF12,TELO2,RFC3,HTATIP2,WIPF1,LANCL1,CSNK1A1,STX16,DHX15,FANCI,MIS12,CDC16,LUC7L3,ATF6,GEMIN4,ABCC1 |
| 1.169e-03 | -6.75 | MODULE_277 | MSigDB lists | MODULE_277 | 52 | 17 | 17377 | 2626 |
USP22,CSNK1A1,IL21R,SCYL2,PAIP2,TAF2,TBC1D14,ZNF639,SLC16A1,FEM1B,LTN1,GTSE1,VCPIP1,CENPT,MAPK1,IFT46,PRPF4B |
| 1.173e-03 | -6.75 | protein phosphatase type 1 complex | cellular component | GO:0000164 | 13 | 7 | 18223 | 2701 |
PPP1R3B,PPP1R11,PPP1R9B,SHOC2,PPP1R2,NCK1,PPP1R15B |
| 1.173e-03 | -6.75 | GSE15330_HSC_VS_GRANULOCYTE_MONOCYTE_PROGENITOR_IKAROS_KO_UP | MSigDB lists | GSE15330_HSC_VS_GRANULOCYTE_MONOCYTE_PROGENITOR_IKAROS_KO_UP | 190 | 45 | 17377 | 2626 |
KIF3B,PIGM,TMEM184B,GADD45G,TMEM109,RAB6A,GGA2,B4GALT4,MIEN1,HAUS2,TFRC,JMY,LMNA,PA2G4,NUP210,NEK6,VMP1,SIAH1,PPME1,FJX1,SLC44A1,GMEB1,RAB4A,MARCH2,SPSB3,PDCL3,TMX1,TIMP2,ATP6V0A1,KRAS,CAPZA2,KRTCAP2,KDM3A,PLEKHF2,CDC16,SYNCRIP,ORMDL2,ATE1,SLC25A19,FAM122A,TRIM32,RBPJ,PLOD3,CPEB2,TSPAN5 |
| 1.173e-03 | -6.75 | GSE17721_0.5H_VS_12H_GARDIQUIMOD_BMDC_DN | MSigDB lists | GSE17721_0.5H_VS_12H_GARDIQUIMOD_BMDC_DN | 190 | 45 | 17377 | 2626 |
UBE2D3,PIGN,TM9SF4,SCYL1,UBE2Z,AGPAT3,DNAJB1,PLXNA1,CCNL2,METTL3,MYEF2,RBM4,CD320,VAV1,RNF121,ATP6V0B,VASP,MLX,ZNF260,MDFIC,MOB1A,UBE2M,MORC3,ACSL5,SRSF11,CAMSAP1,PSMB7,RFFL,DNAJA1,EDEM2,LUC7L,PRDX1,CLK3,RBL1,HNRNPH3,TPP2,PRDX5,SOCS4,FAM122A,NUP62,YY1,RRS1,B4GALT3,USP53,COIL |
| 1.173e-03 | -6.75 | GSE17721_CTRL_VS_CPG_24H_BMDC_DN | MSigDB lists | GSE17721_CTRL_VS_CPG_24H_BMDC_DN | 190 | 45 | 17377 | 2626 |
TMEM106C,ZNF207,KIF3B,RAB14,TP53RK,NUP188,ZNF445,NOP2,TSC2,POLR2K,PRKCSH,MRI1,MOGS,VTI1A,TMED3,LYRM2,PTPN2,NEK6,ZNF639,MCM5,RRBP1,RAD23B,RPF2,TAGLN2,ORC3,LRRC59,PREB,NUDC,MOB4,TMEM115,NSUN2,RDH10,SUGP2,TUBGCP5,MRPL12,RNPS1,OGDH,TOMM40,PSMB9,PI4K2A,RAD51C,PARG,MRFAP1L1,ROCK1,SMAD1 |
| 1.173e-03 | -6.75 | GSE20198_IL12_VS_IL12_IL18_TREATED_ACT_CD4_TCELL_DN | MSigDB lists | GSE20198_IL12_VS_IL12_IL18_TREATED_ACT_CD4_TCELL_DN | 190 | 45 | 17377 | 2626 |
MBD1,SLC12A7,GCLM,TXN,HNRNPUL2,AP3M2,CREBL2,LYN,CHD1,QSOX2,WWP2,PHC2,NRF1,ATP13A3,PRC1,TTC4,ABI1,CCAR1,PHF10,MLEC,NRAS,PGGT1B,POLK,RABIF,MAP7D1,NFATC2,RIT1,PLEC,PTTG1IP,PDE3B,STX16,SH3BP5,DTWD1,EIF4ENIF1,CDC27,PPM1G,PML,GPI,PTPDC1,ZMIZ1,CD81,MAPK1,BRD9,HRAS,SSRP1 |
| 1.173e-03 | -6.75 | GSE11924_TFH_VS_TH1_CD4_TCELL_UP | MSigDB lists | GSE11924_TFH_VS_TH1_CD4_TCELL_UP | 190 | 45 | 17377 | 2626 |
MBD1,AGRN,CAST,FAM53C,TOR3A,ACTR3,MON1B,WDTC1,AGPAT1,MYH9,B4GALT1,LYN,CHD1,RAPGEF6,CYHR1,APLP2,TBC1D22A,KIF13B,CORO1A,CABLES2,MAP3K14,TMEM8A,ABI1,ARID4A,ORAI2,MAP4K3,WBP1,ICAM2,PEF1,POLG2,AP4E1,NDRG3,USP21,TTC33,POLR2A,ALKBH6,GPR137,GALNT2,SPATA2,FAM110A,HIPK2,PQBP1,ARAP1,CBX4,HIGD2A |
| 1.173e-03 | -6.75 | GSE17721_LPS_VS_PAM3CSK4_8H_BMDC_UP | MSigDB lists | GSE17721_LPS_VS_PAM3CSK4_8H_BMDC_UP | 190 | 45 | 17377 | 2626 |
DNAJC2,DNMT3A,TRIP12,AP3M2,PCSK7,HMGN3,NIT2,RGS2,MXD1,NDUFS4,GTF2F1,RBM17,CRKL,CAPN2,USF1,PDCD10,ETV6,RCSD1,H2AFY,CDKN1B,CREB1,MINPP1,HTRA2,ENPP4,BAK1,ARHGAP17,HMGN5,CSRP1,AKT2,NQO2,RFFL,SLBP,MCL1,FXR1,KLF6,SH3GLB1,HLA-B,TXNDC16,FAM110A,MAFK,NAA20,PLOD3,PFKP,ANXA11,RNF114 |
| 1.173e-03 | -6.75 | GSE360_CTRL_VS_L_DONOVANI_DC_UP | MSigDB lists | GSE360_CTRL_VS_L_DONOVANI_DC_UP | 190 | 45 | 17377 | 2626 |
H2AFZ,KIAA0100,GNPDA1,RPS6KA1,HLA-E,PIP4K2A,FAM8A1,CDK5,VAV1,ANKRD26,GART,NDUFV1,PCNA,ZNF473,SLC1A4,MED8,ANP32A,SLC38A10,TARDBP,AHCY,TTC3,KCNAB2,MED22,ABCC5,CSTF1,DDX28,NASP,KAT2A,WDR1,DNAJC9,DDX39A,SYMPK,EIF3H,EIF3K,PFDN5,FASTK,MEGF9,FAU,LTA4H,FAM208A,TAF6,USF2,TOB1,COIL,PDCD4 |
| 1.173e-03 | -6.75 | GSE27786_BCELL_VS_NKTCELL_UP | MSigDB lists | GSE27786_BCELL_VS_NKTCELL_UP | 190 | 45 | 17377 | 2626 |
BCL2L12,ADAM10,SF3B1,CDT1,C16orf87,USP39,GMCL1,DAZAP2,CHD1,FBXL6,RBM34,DUT,POP7,PPCDC,MRPL34,BRI3,RNASEH2A,NAA35,MSH6,MYO5A,CDC5L,YTHDC1,CYTH1,USO1,RHOA,ANKRD37,PPP1R21,MEF2D,CCNF,TAZ,MBD3,DHX15,SMAP2,RAB2B,RDH11,TFEB,NECAP2,CAT,BRWD1,NIP7,PFDN4,PARG,FAM126A,CHEK2,LRCH1 |
| 1.173e-03 | -6.75 | trichilemmoma | COSMIC cancer mutations | trichilemmoma | 7 | 5 | 17385 | 2587 |
FGFR3,KRAS,NRAS,PTEN,HRAS |
| 1.173e-03 | -6.75 | urinary_tract-carcinoma-transitional_cell_carcinoma | COSMIC cancer mutations | urinary_tract-carcinoma-transitional_cell_carcinoma | 7 | 5 | 17385 | 2587 |
FGFR3,KRAS,NRAS,HRAS,MSH6 |
| 1.173e-03 | -6.75 | skin-adnexal_tumour-trichilemmoma | COSMIC cancer mutations | skin-adnexal_tumour-trichilemmoma | 7 | 5 | 17385 | 2587 |
FGFR3,KRAS,NRAS,PTEN,HRAS |
| 1.173e-03 | -6.75 | pituitary-adenoma-multihormonal | COSMIC cancer mutations | pituitary-adenoma-multihormonal | 7 | 5 | 17385 | 2587 |
KRAS,NRAS,HRAS,AXIN1,CDKN2A |
| 1.173e-03 | -6.75 | cervix-carcinoma-endometrioid_adenocarcinoma | COSMIC cancer mutations | cervix-carcinoma-endometrioid_adenocarcinoma | 7 | 5 | 17385 | 2587 |
GNAS,KRAS,STK11,NRAS,PTEN |
| 1.175e-03 | -6.75 | GO_MITOTIC_CYTOKINESIS | MSigDB lists | GO_MITOTIC_CYTOKINESIS | 31 | 12 | 17377 | 2626 |
PLK1,RHOA,SNX18,CEP55,ANK3,KIF23,CHMP4B,NUSAP1,RACGAP1,CNTROB,ANLN,STMN1 |
| 1.175e-03 | -6.75 | AMIT_SERUM_RESPONSE_480_MCF10A | MSigDB lists | AMIT_SERUM_RESPONSE_480_MCF10A | 31 | 12 | 17377 | 2626 |
COPS8,HSPBP1,MCM10,SIGMAR1,CD3EAP,TIMM23,PARG,SSNA1,SLC26A2,CYB5R1,B4GALT4,ZBTB24 |
| 1.185e-03 | -6.74 | SAFB2 (scaffold attachment factor B2) | protein interactions | 9667 | 53 | 18 | 17029 | 2761 |
COX15,MPHOSPH8,DHPS,RB1CC1,SUZ12,CUL3,TOPORS,VDAC1,MATR3,GIT2,CAND1,FNTA,MEX3C,CLK3,RBMX,SAFB,FUS,CCAR1 |
| 1.185e-03 | -6.74 | POLDIP3 (DNA polymerase delta interacting protein 3) | protein interactions | 84271 | 53 | 18 | 17029 | 2761 |
SARNP,NQO1,THOC1,RPS6KA1,BCLAF1,EIF4G2,FERMT3,ERH,GOLGA2,KLHL20,EIF4A3,ZNF746,USP20,RNASEH2A,POT1,IFI16,SRPK2,TERF2 |
| 1.185e-03 | -6.74 | GTF2IRD1 (GTF2I repeat domain containing 1) | protein interactions | 9569 | 53 | 18 | 17029 | 2761 |
DCAF6,ZMYM5,TOR1AIP1,ATP2C1,BRCA1,ZMYM3,CBX3,USF1,KPNA4,SMAD2,KPNA1,SYNCRIP,PIAS2,INTS12,USP20,KIFAP3,KPNA2,PPP2R2D |
| 1.185e-03 | -6.74 | U2SURP (U2 snRNP associated SURP domain containing) | protein interactions | 23350 | 53 | 18 | 17029 | 2761 |
RBM17,RPA2,RPS2,CYLD,CTNNBL1,CHERP,MFAP1,CUL3,CUL1,JMJD6,TARDBP,SF3A2,RPSA,LMNA,RPA1,DDX42,CDC5L,CAND1 |
| 1.185e-03 | -6.74 | UQCRC1 (ubiquinol-cytochrome c reductase core protein 1) | protein interactions | 7384 | 53 | 18 | 17029 | 2761 |
NDUFV2,PHB2,ILF3,KRAS,CYCS,DNAJA1,ATP5F1B,PLEC,MCM2,VDAC1,SDHA,UQCRH,RUVBL2,NDUFS5,LMAN1,ATF2,POC5,DCTN1 |
| 1.186e-03 | -6.74 | nucleotide-excision repair, DNA incision | biological process | GO:0033683 | 39 | 14 | 17256 | 2622 |
RPA2,ERCC1,RFC3,PCNA,RBX1,POLK,RPS27A,XPA,CHD1L,RFC2,GTF2H2,OGG1,DDB1,RPA1 |
| 1.187e-03 | -6.74 | GSE32901_NAIVE_VS_TH17_NEG_CD4_TCELL_UP | MSigDB lists | GSE32901_NAIVE_VS_TH17_NEG_CD4_TCELL_UP | 164 | 40 | 17377 | 2626 |
TRAF7,CLSPN,B4GALT5,FAM129A,VAV2,TPX2,KIF23,NUF2,HMGN3,TCF19,LYN,NUP205,DTL,IRF4,CCNA2,PRC1,GTSE1,KNTC1,MVP,ZNRD1,S100A6,IMPA2,CYFIP1,TK1,KIF15,MKI67,CKAP2L,USP10,CDCA2,CCNF,ANLN,SHCBP1,ODC1,KIF11,ASF1B,DDOST,ERGIC3,ADAM9,FAM126A,EHD4 |
| 1.187e-03 | -6.74 | Nucleotide Metabolism | WikiPathways | WP404 | 19 | 9 | 5312 | 837 |
ADSS,SRM,MTHFD2,PRPS2,RRM1,IMPDH1,RRM2,ADSL,OAZ1 |
| 1.189e-03 | -6.73 | Glyco_transf_7C | pfam domains | PF02709 | 7 | 5 | 17054 | 2545 |
B4GALT1,B4GALT4,B4GALT3,B4GALT5,B4GALT2 |
| 1.189e-03 | -6.73 | Glyco_transf_7N | pfam domains | PF13733 | 7 | 5 | 17054 | 2545 |
B4GALT1,B4GALT4,B4GALT3,B4GALT5,B4GALT2 |
| 1.190e-03 | -6.73 | PI3K-AKT-mTOR signaling pathway and therapeutic opportunities | WikiPathways | WP3844 | 30 | 12 | 5312 | 837 |
NRAS,TSC2,PTEN,RB1CC1,PIK3R2,CDKN1B,ATG13,KRAS,HRAS,FOXO3,RHEB,TFEB |
| 1.192e-03 | -6.73 | POMEROY_MEDULLOBLASTOMA_DESMOPLASIC_VS_CLASSIC_UP | MSigDB lists | POMEROY_MEDULLOBLASTOMA_DESMOPLASIC_VS_CLASSIC_UP | 61 | 19 | 17377 | 2626 |
ABL2,NUCB1,SMAD2,POLR2J,ACOX1,CPOX,ACLY,E2F1,ARL6IP1,LDHA,SEPT8,RPN2,PLEC,TP53BP2,USP11,BCAP31,LRP8,PRDX1,GPX4 |
| 1.195e-03 | -6.73 | CCTGCTG,MIR-214 | MSigDB lists | CCTGCTG,MIR-214 | 222 | 51 | 17377 | 2626 |
RAB14,LUZP1,TRIP10,FAM53C,ARID5A,WDTC1,PLAGL2,HMGN3,TGOLN2,EZH1,CDIPT,MYEF2,HMG20A,PHC2,CRKL,RAB35,PPME1,RIMS3,SSBP3,JAZF1,SEC24C,CRY2,CPSF4,GNAI2,IFT46,CELSR2,BAZ2A,C16orf72,SIGMAR1,OXR1,RTF1,FAM133B,CADM1,GALNT7,LY6E,HAGH,MARK2,PHF6,BTBD1,RAD54B,SRSF1,ALKBH6,SOCS7,TMED10,PDRG1,PTER,MYO18A,ACLY,CHMP4B,YWHAZ,SMARCD1 |
| 1.196e-03 | -6.73 | phagosome acidification | biological process | GO:0090383 | 27 | 11 | 17256 | 2622 |
ATP6V0B,ATP6V1D,RAB7A,ATP6V0A2,ATP6V0A1,ATP6V0C,ATP6V1C1,ATP6V1B2,ATP6V0E1,ATP6V0D1,ATP6V1G1 |
| 1.199e-03 | -6.73 | MODULE_97 | MSigDB lists | MODULE_97 | 89 | 25 | 17377 | 2626 |
FYTTD1,SNRNP200,NRAS,KLF10,MIOS,TACC1,NSUN2,DBF4,SLC25A22,DCLRE1C,RLF,SEC16A,SCYL2,DHX15,NUP205,CRKL,MDM2,INTS7,SEC24C,KLHL15,PTPN11,AEN,GLCCI1,PURA,NMD3 |
| 1.199e-03 | -6.73 | MORF_PPP5C | MSigDB lists | MORF_PPP5C | 89 | 25 | 17377 | 2626 |
PHF10,ZNF500,SIGMAR1,KLHL18,CDK13,NKRF,UBE4B,BRCA1,MTX1,PCGF1,CCNF,PDXDC1,FANCI,SSR1,TAF2,RAP1A,GALNT2,CHD3,PIK3R2,MEA1,ATP6V0A2,WDR62,PPP5C,CPSF4,CAMK2G |
| 1.200e-03 | -6.73 | MRPS21 (mitochondrial ribosomal protein S21) | protein interactions | 54460 | 33 | 13 | 17029 | 2761 |
COX15,RPLP2,RBM42,MRPS15,HNRNPR,USP42,RPL6,MRPS27,CUL3,TRMT10B,DUSP11,ZC3H3,CAND1 |
| 1.200e-03 | -6.73 | RBM15B (RNA binding motif protein 15B) | protein interactions | 29890 | 33 | 13 | 17029 | 2761 |
DDX47,THOC1,SUZ12,CDC23,USP11,RBM15,TERF1,MATR3,METTL3,DHX15,ISG15,TERF2,SRPK2 |
| 1.200e-03 | -6.73 | CNOT6 (CCR4-NOT transcription complex subunit 6) | protein interactions | 57472 | 33 | 13 | 17029 | 2761 |
CNOT9,ATXN3,GADD45B,AGO2,CNOT6,CAPZA2,CNOT6L,CNOT11,PABPC1,ZMAT3,TOB1,CNOT3,CHAF1A |
| 1.200e-03 | -6.73 | TNRC6C (trinucleotide repeat containing 6C) | protein interactions | 57690 | 33 | 13 | 17029 | 2761 |
ODF2,AGO2,HNRNPUL2,CUL3,CNOT6,BRCA1,CNTROB,CNOT6L,PABPC1,PABPC4,CNOT3,DEF6,CAND1 |
| 1.200e-03 | -6.73 | C9orf78 (chromosome 9 open reading frame 78) | protein interactions | 51759 | 33 | 13 | 17029 | 2761 |
TERF2IP,C9orf78,SNRNP200,EWSR1,HARS,EFTUD2,HEXA,SMURF1,NKAPD1,H2AFV,APP,LMNA,BTBD1 |
| 1.200e-03 | -6.73 | ERAL1 (Era like 12S mitochondrial rRNA chaperone 1) | protein interactions | 26284 | 33 | 13 | 17029 | 2761 |
MRPS2,TCF3,CUL3,NDUFA4,XRCC3,NFATC2,FUS,FAM50B,HNRNPDL,ZC3H3,ATPAF1,CDC5L,CAND1 |
| 1.200e-03 | -6.73 | UNC93B1 (unc-93 homolog B1, TLR signaling regulator) | protein interactions | 81622 | 33 | 13 | 17029 | 2761 |
CLPTM1,FARSA,PIGN,DDOST,SCAMP3,SURF4,STT3A,SEL1L,TM9SF3,CDIPT,ANKHD1,ABCC1,FDFT1 |
| 1.201e-03 | -6.72 | stomach-adenoma | COSMIC cancer mutations | stomach-adenoma | 13 | 7 | 17385 | 2587 |
GNAS,TSC1,KRAS,NRAS,TSC2,HRAS,CDKN2A |
| 1.201e-03 | -6.72 | endometrium-ovary-endometriosis | COSMIC cancer mutations | endometrium-ovary-endometriosis | 13 | 7 | 17385 | 2587 |
FGFR3,KRAS,ARID1A,BRCA1,NRAS,PTEN,HRAS |
| 1.202e-03 | -6.72 | response to topologically incorrect protein | biological process | GO:0035966 | 184 | 44 | 17256 | 2622 |
HSPH1,ATXN3,ADD1,SEC61G,CXXC1,DNAJB2,SDF2L1,DNAJB1,RHBDD1,DNAJB9,LMNA,SSR1,RNF121,SHC1,MYDGF,PDIA6,ATP6V0D1,CTDSP2,RNF5,PREB,DCTN1,BAK1,SEC61B,ERO1A,CUL3,DNAJA1,SYVN1,EDEM2,HERPUD2,SERP1,HSPA1B,OPTN,MFN2,DERL1,SEC31A,ANKZF1,YIF1A,HSPA4,SEC61A1,TATDN2,KLHL15,ASNA1,ATF6,CLU |
| 1.203e-03 | -6.72 | Ras | pfam domains | PF00071 | 135 | 34 | 17054 | 2545 |
RHOG,RAB14,RAB11B,RHOC,RAC1,RAB23,RAB6A,IFT27,RAB11A,RAB8A,RAB21,RAP1A,CDC42,RALB,RAB35,RAB4A,RHOBTB3,NRAS,RHOA,RAB7A,KRAS,RIT1,RAB1A,RHOT1,RAB5B,RHOT2,RAB22A,RAB2B,RHOB,RHEB,RAB18,RAB24,HRAS,RHEBL1 |
| 1.206e-03 | -6.72 | Galactosyl_T_C | interpro domains | IPR027791 | 7 | 5 | 18492 | 2768 |
B4GALT1,B4GALT3,B4GALT4,B4GALT5,B4GALT2 |
| 1.206e-03 | -6.72 | Galactosyl_T | interpro domains | IPR003859 | 7 | 5 | 18492 | 2768 |
B4GALT1,B4GALT3,B4GALT4,B4GALT5,B4GALT2 |
| 1.206e-03 | -6.72 | Galactosyl_T_N | interpro domains | IPR027995 | 7 | 5 | 18492 | 2768 |
B4GALT1,B4GALT3,B4GALT4,B4GALT5,B4GALT2 |
| 1.208e-03 | -6.72 | GSE27786_LSK_VS_NKTCELL_UP | MSigDB lists | GSE27786_LSK_VS_NKTCELL_UP | 185 | 44 | 17377 | 2626 |
MIF,TMEM106C,CHERP,NDUFAF2,FLYWCH2,ORC1,MAPK14,FBXO3,PDXP,CCNA2,IARS,MCM5,INTS1,SUCLG2,BRI3,LDLRAD3,HTRA2,LDHB,NUDC,PLK1,DCAF8,ACSL3,NSUN2,NUP155,TOPORS,CDCA2,BRCA1,GUF1,ZFAND5,GLOD4,EPRS,PWWP2B,TRIM47,PEX5,CCDC86,OSBPL8,EIF2D,PPA2,ADAM9,RUVBL2,ACADM,CDK2,C11orf1,MZT2B |
| 1.208e-03 | -6.72 | GSE13229_IMM_VS_MATURE_NKCELL_DN | MSigDB lists | GSE13229_IMM_VS_MATURE_NKCELL_DN | 185 | 44 | 17377 | 2626 |
TMEM106C,NSMCE4A,SCAMP3,TM9SF4,GPBP1L1,UQCR10,CHD1L,SNX15,CERK,AGPAT3,ARF1,USP48,MAPK14,RHBDD1,PIP5K1C,RPA2,PIK3R2,ARHGEF2,INTS12,GLE1,CYB5R1,SAP30L,TGFB1,ZNF524,ORAI2,EXOSC6,MKLN1,KLF10,NQO2,AKT2,PACS1,EIF2AK1,AMDHD2,ISG15,MAPK3,RPL36,TIMM13,AGPAT2,GPS2,MPV17,MLYCD,WIPI2,TSPAN5,DCAF5 |
| 1.208e-03 | -6.72 | GSE31082_CD4_VS_CD8_SP_THYMOCYTE_DN | MSigDB lists | GSE31082_CD4_VS_CD8_SP_THYMOCYTE_DN | 185 | 44 | 17377 | 2626 |
SLC12A7,SRM,PKP4,B4GALT5,CDT1,TMEM97,RMI2,SIKE1,BLM,RSAD1,PABPC4,SAC3D1,PA2G4,NEK6,CD3EAP,ATIC,RAD23B,NUP107,TIMELESS,CENPM,PRADC1,F2R,PPA1,TRIM14,EEF1D,GINS1,ACSL5,POU2AF1,NXT1,TIGD5,CDC6,EIF2A,ESYT1,MEN1,RFC2,SF3A2,SMAP2,HAUS8,SLC19A1,AHNAK,HINT1,CABIN1,SCARB1,FAF1 |
| 1.208e-03 | -6.72 | GSE17721_POLYIC_VS_CPG_16H_BMDC_DN | MSigDB lists | GSE17721_POLYIC_VS_CPG_16H_BMDC_DN | 185 | 44 | 17377 | 2626 |
MMACHC,HSPH1,MRPL42,HJURP,CDK2AP2,COPE,CSNK2A1,NUF2,PPP3CB,TMEM165,STMN1,FAM8A1,CSDE1,NUS1,NOL11,RPL19,OSTC,PIKFYVE,PRADC1,MED22,FDFT1,ACSL5,AMPD2,EIF3L,MLEC,GOPC,NARF,RABIF,ATP6V0A1,GLO1,SEPT7,SERP1,SNRPA,CYB5A,ORMDL2,SURF4,PRDX3,BIRC5,ACOX1,CTBS,LRPPRC,PGRMC1,PPP5C,AAAS |
| 1.208e-03 | -6.72 | GSE5589_LPS_VS_LPS_AND_IL10_STIM_IL6_KO_MACROPHAGE_45MIN_UP | MSigDB lists | GSE5589_LPS_VS_LPS_AND_IL10_STIM_IL6_KO_MACROPHAGE_45MIN_UP | 185 | 44 | 17377 | 2626 |
TMEM106C,ZBED3,PIGQ,MAGED1,TMX4,CDC42SE2,AKT1S1,EZH1,ASXL2,FOXO3,PDXDC1,COPG2,XPR1,ANKRD28,APLP2,CDKN1B,FNIP2,GLTP,PIKFYVE,SPTSSA,LRSAM1,RNLS,CGGBP1,ABCC1,TSPAN31,SLC16A7,PIP4K2C,SLC17A5,RAB5B,USP21,POLR2A,MAPK3,WDR11,QARS,APPL2,NUP62,RUFY3,WDR62,TMEM159,USF2,ARHGAP23,CHPF2,PTOV1,DDX42 |
| 1.208e-03 | -6.72 | GSE2197_CPG_DNA_VS_UNTREATED_IN_DC_DN | MSigDB lists | GSE2197_CPG_DNA_VS_UNTREATED_IN_DC_DN | 185 | 44 | 17377 | 2626 |
ST13,MRPS26,ABCB10,DUSP22,FOXO3,APOPT1,ATPAF1,PDXP,ZBTB45,IL6ST,DNAAF2,BDH1,RPAP1,CDC25B,ALDH18A1,SLC35C2,CNPY3,IFT46,KCNAB2,TIMP2,FAM172A,POLR2G,KAT7,HELB,MFNG,CCDC34,WDHD1,ANLN,BORA,TRIM28,TTC33,ANKRD46,BTBD1,WDR11,RAD18,ORMDL2,GPS2,CORO1C,PPA2,ZNF436,QRSL1,SSNA1,NCOA1,GCSH |
| 1.208e-03 | -6.72 | ERB2_UP.V1_DN | MSigDB lists | ERB2_UP.V1_DN | 185 | 44 | 17377 | 2626 |
DDX58,RECQL,ZBTB10,RRP15,DEPDC1,CASP6,DBF4,ZNF107,ZNF267,NCAPG,RMI1,CHD1,MRPL19,FBXO5,KRR1,DTL,RRN3,SMC3,ADD3,ZCCHC2,MSH2,LTN1,BCL2,SLC26A2,MYBL1,RPAP3,RPRD1A,RHOBTB3,ZNF84,KLF10,RAD51AP1,NOL8,CPOX,WIPF1,MAP4K3,RAD54B,TAF2,GOLGA4,BRWD1,GOLGA8A,C1orf109,ADAM9,ZBTB11,CCDC59 |
| 1.208e-03 | -6.72 | GSE17301_ACD3_ACD28_VS_ACD3_ACD28_AND_IFNA2_STIM_CD8_TCELL_UP | MSigDB lists | GSE17301_ACD3_ACD28_VS_ACD3_ACD28_AND_IFNA2_STIM_CD8_TCELL_UP | 185 | 44 | 17377 | 2626 |
H2AFZ,DEPDC1,PXMP2,RGS2,STMN1,TTF1,CD320,BCAT2,RAD23A,KRI1,PSMA6,GRSF1,SSBP3,RAB4A,NAA50,YBX1,CYC1,PDIA6,MICAL3,MSH6,SRSF10,TK1,PRKDC,ABCF2,DNAJC9,GLO1,BRCA1,SERP1,SNRPA,ZNF282,KIF18A,HSPBP1,POLE,HINT1,ACYP1,KHSRP,HMGB2,STK11,BTF3,GPI,RUFY3,TFDP2,MRPL3,USP13 |
| 1.208e-03 | -6.72 | GSE30083_SP1_VS_SP4_THYMOCYTE_DN | MSigDB lists | GSE30083_SP1_VS_SP4_THYMOCYTE_DN | 185 | 44 | 17377 | 2626 |
SLC12A7,MANBA,B4GALT5,PIGQ,FAM129A,ANKH,GNE,TAP1,CREBL2,CDIPT,CRLF3,IL21R,PARN,APP,RAB21,CTSS,ADD3,NUP210,ABCD1,STAT3,GM2A,ADCY7,TRAFD1,SELPLG,PRKDC,PPP1R21,SCFD2,PLEKHM3,RAB3IP,PDE3B,NDRG3,INF2,MKNK1,SGSH,AHNAK,TTC13,APPL2,NLRC5,MLYCD,LY75,MAP3K5,TRAF5,ABCA1,ALS2 |
| 1.208e-03 | -6.72 | GSE10239_NAIVE_VS_KLRG1HIGH_EFF_CD8_TCELL_DN | MSigDB lists | GSE10239_NAIVE_VS_KLRG1HIGH_EFF_CD8_TCELL_DN | 185 | 44 | 17377 | 2626 |
GNPDA1,C1orf112,CDCA8,SDF2L1,SNRPD3,AP3S1,TMEM165,STMN1,PMVK,HLA-A,SPAG5,FKBP1A,CAPN2,RFWD3,SLC1A4,MCM5,PRC1,KIF22,KNTC1,SGCB,TACC3,MYO5A,SAP30,CYFIP1,MAPRE2,TK1,ELL2,PBK,RAD51AP1,MRPS10,CCDC34,AURKB,ANLN,RAD51C,NEIL3,NSMCE2,CDCA5,PGRMC1,KPNA2,PKD2,NAA20,NDE1,LRP8,SLC25A33 |
| 1.208e-03 | -6.72 | GSE42021_TCONV_PLN_VS_CD24LO_TCONV_THYMUS_UP | MSigDB lists | GSE42021_TCONV_PLN_VS_CD24LO_TCONV_THYMUS_UP | 185 | 44 | 17377 | 2626 |
CCDC93,MRPL42,MRPS15,AGTRAP,IVNS1ABP,DNAJB2,TAP1,VPS45,DLGAP4,LAGE3,CUL1,KIF2C,GYG1,ABHD14A,PARK7,EBP,GSTK1,CLIC4,TBC1D14,RNASEK,ARHGEF1,XPA,CDKN1B,ZBTB22,SLC38A10,CPSF4,SPTSSA,LPCAT1,RNF5,CYFIP1,TUFM,MCL1,CCNF,HAGH,ARF4,HSPB11,TMEM168,WNT5B,NFIL3,MAP4,MLYCD,ATE1,FKBP5,PDCD4 |
| 1.208e-03 | -6.72 | GSE17721_CTRL_VS_PAM3CSK4_6H_BMDC_DN | MSigDB lists | GSE17721_CTRL_VS_PAM3CSK4_6H_BMDC_DN | 185 | 44 | 17377 | 2626 |
WSB2,GNPNAT1,DHPS,SEC61G,MECP2,FAM129A,PLAGL2,BCL2L1,METTL3,SRXN1,FKBP1A,LYAR,PA2G4,SLC31A1,PSMA6,EIF2S2,TNFAIP8,UCHL5,SLC44A1,PTPN11,CS,GEMIN6,TRA2B,ANXA5,MDFIC,LRRC59,ABI1,UBE2M,NUDC,MOB4,ELL2,HARS,PSMB7,PITPNB,TANC1,ZFR,MAGED2,ATP1A1,NIP7,HNRNPH3,MAPK6,ZNF436,PPP2R2D,IPO4 |
| 1.208e-03 | -6.72 | GSE37416_0H_VS_48H_F_TULARENSIS_LVS_NEUTROPHIL_UP | MSigDB lists | GSE37416_0H_VS_48H_F_TULARENSIS_LVS_NEUTROPHIL_UP | 185 | 44 | 17377 | 2626 |
PPP1R12A,UBR2,TOR1AIP1,WDTC1,SDC2,AGPAT1,ACAP1,GLUD1,NOTCH2,CRLF3,LCLAT1,FAM8A1,PRPF18,ZNF92,SEC11A,SNX18,TBC1D14,CNN2,CNPY3,ALDH9A1,KDM3B,PHF20L1,TIMP2,NASP,SNX2,TACC1,PRKDC,WIPF1,TOPORS,RFC2,STK17B,SMAP2,SCAP,SNAP23,STK38,UBXN2B,OAZ2,MEGF9,ARRDC1,CAB39,ATF6,KPNA2,CHPT1,ZC3HAV1 |
| 1.208e-03 | -6.72 | GSE37416_0H_VS_6H_F_TULARENSIS_LVS_NEUTROPHIL_DN | MSigDB lists | GSE37416_0H_VS_6H_F_TULARENSIS_LVS_NEUTROPHIL_DN | 185 | 44 | 17377 | 2626 |
NCOR2,CYLD,IVNS1ABP,HMGXB3,TMEM41B,SRGN,GADD45G,TRAK1,CERK,TOP2B,ZNF267,SLC35B2,FKBP2,SNN,RLF,TFRC,RNF103,PSMA6,BRPF3,ATP13A3,PPCDC,PIK3IP1,TIPARP,PABPC1,SAMD4B,BRD4,GUK1,KLF10,ETV3,ELL2,KDM3A,ABCF1,SERP1,GINS4,CHMP4A,ATP1A1,MFAP1,HPS5,MAPK6,PTPN7,ATXN2L,CHMP4B,RBPJ,ZMIZ1 |
| 1.209e-03 | -6.72 | gamma-tubulin complex | cellular component | GO:0000930 | 20 | 9 | 18223 | 2701 |
MZT2A,MZT1,CENPJ,MECP2,TUBGCP5,TOPORS,BRCA1,TUBGCP2,MZT2B |
| 1.209e-03 | -6.72 | U1 snRNP | cellular component | GO:0005685 | 20 | 9 | 18223 | 2701 |
SNRPB,LUC7L3,SNRPG,PRPF39,SNRNP70,SNRPD3,LUC7L,SNRPA,LUC7L2 |
| 1.210e-03 | -6.72 | CENPX (centromere protein X) | protein interactions | 201254 | 22 | 10 | 17029 | 2761 |
FANCL,RPA2,MDM2,FAAP100,CNTROB,BLM,FANCE,RMI1,CENPU,RPA1 |
| 1.210e-03 | -6.72 | C16orf87 (chromosome 16 open reading frame 87) | protein interactions | 388272 | 22 | 10 | 17029 | 2761 |
CDC16,CDC27,MIER1,H2AFX,ANAPC2,MIER2,ANAPC7,CDC23,HDAC2,ANAPC4 |
| 1.210e-03 | -6.72 | GNMT (glycine N-methyltransferase) | protein interactions | 27232 | 22 | 10 | 17029 | 2761 |
TERF2IP,HUWE1,WDYHV1,HDAC7,PRKACA,TERF1,POT1,PLEKHF2,RPSA,TERF2 |
| 1.210e-03 | -6.72 | Bach1 (BTB and CNC homology 1, basic leucine zipper transcription factor 1) | protein interactions | 12013 | 22 | 10 | 17029 | 2761 |
TTC3,ARF1,MAGT1,SYNM,SLC12A2,MRPL3,MAFK,DYNLL1,HEXB,FAM83D |
| 1.210e-03 | -6.72 | GINS2 (GINS complex subunit 2) | protein interactions | 51659 | 22 | 10 | 17029 | 2761 |
GINS1,CSNK1G2,AHSA1,RPS6KA1,H2AFX,CTSA,CHEK2,EIF4H,GINS4,CAPN1 |
| 1.210e-03 | -6.72 | P2RX5 (purinergic receptor P2X 5) | protein interactions | 5026 | 22 | 10 | 17029 | 2761 |
PBXIP1,TIMM17A,PDS5B,TNPO3,FAM126A,TTC17,WDR45B,STK17B,DNAJB9,TMEM131 |
| 1.210e-03 | -6.72 | Gorasp1 (golgi reassembly stacking protein 1) | protein interactions | 74498 | 22 | 10 | 17029 | 2761 |
TMED7,USO1,GOLGA2,RNASEH2C,TMED10,GORASP1,KIF14,GLUD1,SEC16A,TMED2 |
| 1.210e-03 | -6.72 | FIBP (FGF1 intracellular binding protein) | protein interactions | 9158 | 22 | 10 | 17029 | 2761 |
MIF,CDK5,PCNA,OGT,CSNK2A1,GEMIN4,CABLES2,APP,C2CD5,CABLES1 |
| 1.210e-03 | -6.72 | RSRP1 (arginine and serine rich protein 1) | protein interactions | 57035 | 22 | 10 | 17029 | 2761 |
FAM192A,RBM23,CLK3,MRS2,TNPO3,DMWD,APP,PACS2,TWISTNB,SRPK2 |
| 1.214e-03 | -6.71 | cofactor biosynthetic process | biological process | GO:0051188 | 221 | 51 | 17256 | 2622 |
GALK1,NADSYN1,COX15,MMACHC,GCLM,PPCS,UROD,CHAC2,ADPGK,SPR,RSAD1,MAT2B,FLAD1,GART,COQ4,ATIC,PPCDC,TECR,TMEM14C,RNLS,SLC25A1,ACSL5,ELOVL5,ATP5IF1,COQ8A,PPT1,COQ10B,ACSL3,CPOX,LDHA,NADK2,OGDH,PKM,HAGH,PDHX,MPC1,MAT2A,MBIP,ACLY,NAXE,ACAT1,DHTKD1,MLYCD,GPI,DHFR2,PDXK,PARP10,PGAM1,SLC25A39,PDSS2,PFKP |
| 1.216e-03 | -6.71 | CIAO1 (cytosolic iron-sulfur assembly component 1) | protein interactions | 9391 | 79 | 24 | 17029 | 2761 |
POLA2,CTU2,TSC2,PRIM2,CHD1L,TYW1,DNAAF5,ELP4,WBP1,WDR5,GLRX3,MAK16,CDC73,APP,PRIM1,GOLM1,PAF1,TSC1,POLE,NSRP1,ELP5,MCM5,CTR9,USP11 |
| 1.216e-03 | -6.71 | CD70 (CD70 molecule) | protein interactions | 970 | 79 | 24 | 17029 | 2761 |
NOP9,INTS2,IFRD1,DEPDC1,TBRG4,UBE4A,USP22,DCUN1D5,XPO7,RUFY1,SPPL2B,MAP2K2,PDXDC1,UTP20,SLC31A1,PLAA,NOL11,NUP107,PDS5B,TIMELESS,TNPO3,NR2F2,CHPT1,NUP85 |
| 1.216e-03 | -6.71 | SUMO4 (small ubiquitin-like modifier 4) | protein interactions | 387082 | 79 | 24 | 17029 | 2761 |
TXNL1,CCT2,IDH3A,HNRNPF,ARHGDIB,UBE2V1,DNAJA1,ATP5F1B,VDAC1,PITHD1,RPSA,LMNA,HSPA1B,STOML2,CAT,PA2G4,PRDX3,STAT1,ACADM,PDIA6,STAT3,PPA1,STRAP,LDHB |
| 1.216e-03 | -6.71 | TAF1 (TATA-box binding protein associated factor 1) | protein interactions | 6872 | 79 | 24 | 17029 | 2761 |
MAX,EWSR1,CSNK2A1,KRAS,EDF1,MEN1,UBE2I,GAR1,ASF1B,GTF2F1,TAF2,BRMS1,UBTF,RB1,SUB1,MDM2,CCNA2,RBL1,TBPL1,CHMP4B,KIFAP3,TAF12,TAF6,SPTAN1 |
| 1.219e-03 | -6.71 | purine ribonucleotide biosynthetic process | biological process | GO:0009152 | 148 | 37 | 17256 | 2622 |
GALK1,COX5B,PPCS,SLC35B2,ATP5F1B,ADPGK,ATP5PF,GART,ATIC,ADCY9,PPCDC,ATP6V0A2,SLC26A2,CYC1,ADCY7,AMPD2,TGFB1,GUK1,LDHA,ATP6V0A1,ADSL,OGDH,ATP5MF,PKM,STOML2,ADSS,ATP5MC3,GUCY1B1,PRPS2,DHTKD1,ACAT1,IMPDH1,ATP5F1A,GPI,NIPSNAP2,PGAM1,PFKP |
| 1.222e-03 | -6.71 | ELM2 | pfam domains | PF01448 | 13 | 7 | 17054 | 2545 |
RCOR1,MIER2,TRERF1,RCOR3,MTA1,MTA2,MIER1 |
| 1.226e-03 | -6.70 | Non-small cell lung cancer | KEGG pathways | ko05223 | 58 | 19 | 7161 | 1149 |
PDPK1,NRAS,RAF1,AKT2,E2F3,KRAS,FOXO3,MAP2K2,EML4,MAPK3,RXRB,RB1,PIK3R2,E2F1,E2F2,MAPK1,STAT3,HRAS,CDKN2A |
| 1.226e-03 | -6.70 | Non-small cell lung cancer | KEGG pathways | hsa05223 | 58 | 19 | 7161 | 1149 |
PDPK1,NRAS,RAF1,AKT2,E2F3,KRAS,FOXO3,MAP2K2,EML4,MAPK3,RXRB,RB1,PIK3R2,E2F1,E2F2,MAPK1,STAT3,HRAS,CDKN2A |
| 1.226e-03 | -6.70 | negative regulation of organelle assembly | biological process | GO:1902116 | 35 | 13 | 17256 | 2622 |
CHMP2A,CHMP4A,FEZ2,CCP110,KAT2A,PHF23,MAP4,DNM2,ARHGEF2,CHMP4B,BRCA1,BECN1,SMAD4 |
| 1.227e-03 | -6.70 | IPO9 (importin 9) | protein interactions | 55705 | 88 | 26 | 17029 | 2761 |
UNK,PDCD6IP,GNPDA1,PRKCSH,IDH3A,HEXB,TUFM,RAB1A,APP,USP5,CAND1,MCTS1,RPN1,EPRS,PSMD2,NAP1L1,KPNA4,CENPJ,ZNF746,H2AFX,RPAP1,TNPO3,XRCC3,RPN2,DCTN1,CDC5L |
| 1.229e-03 | -6.70 | CARS (cysteinyl-tRNA synthetase) | protein interactions | 833 | 49 | 17 | 17029 | 2761 |
KARS,LARS,SUMO2,JMJD6,PAWR,MCFD2,XPO7,PICALM,APP,CAND1,IDE,HSPA4,GART,PPM1G,EEF1D,FAF1,LUC7L2 |
| 1.229e-03 | -6.70 | MCC (mutated in colorectal cancers) | protein interactions | 4163 | 49 | 17 | 17029 | 2761 |
SNRNP200,STRIP1,VHL,STRN4,EZR,ERBIN,VDAC1,APP,TARS,EIF3A,EPRS,PSMD2,PDCD10,IARS,LTA4H,CSNK1D,PFKP |
| 1.229e-03 | -6.70 | SEC24B (SEC24 homolog B, COPII coat complex component) | protein interactions | 10427 | 49 | 17 | 17029 | 2761 |
LUZP1,CUL3,TMEM216,BRCA1,PLEC,MCM2,SEC16A,EVC2,SEC31A,SCAP,CENPJ,RAD23B,GTSE1,MRM3,RNF139,PTPRK,TERF2 |
| 1.234e-03 | -6.70 | regulation of viral release from host cell | biological process | GO:1902186 | 31 | 12 | 17256 | 2622 |
CHMP2A,TRIM26,TRIM8,SMC3,TRIM11,PML,CHMP4B,TRIM32,VPS4A,CHMP2B,TRIM28,DDB1 |
| 1.236e-03 | -6.70 | GSE21063_CTRL_VS_ANTI_IGM_STIM_BCELL_3H_DN | MSigDB lists | GSE21063_CTRL_VS_ANTI_IGM_STIM_BCELL_3H_DN | 154 | 38 | 17377 | 2626 |
ADAM10,SUZ12,DHX9,SUMF1,GMCL1,LANCL1,RLF,MAP1LC3B,ZADH2,LIN9,PDCD10,DUT,NUP107,BTF3L4,ARL6IP1,ARID4A,TSHZ1,CLCN3,GABPA,GALNT7,TOLLIP,HAGH,RAB22A,RPA1,SUGP1,SLCO4A1,DAP3,DCK,SETD3,CBWD1,NCOA1,WIPI2,RPS6KC1,MRPL13,USP53,ABCA1,EYA2,PFKP |
| 1.237e-03 | -6.70 | negative regulation of catabolic process | biological process | GO:0009895 | 275 | 61 | 17256 | 2622 |
USP7,FEZ2,TSC2,KDM4A,PHF23,DAP,UBXN1,PRKAA1,DHX9,SECISBP2,THRAP3,SIRT2,BECN1,MAPK14,PARN,PSEN1,RIC1,PARK7,MAD2L2,PAIP1,RPL11,TIGAR,PIN1,TBC1D14,AXIN2,BCL2,YBX1,TARDBP,STAT3,SENP1,PABPC1,HTRA2,PDCL3,RNF5,RYBP,UBQLN4,LARS,TIMP2,PBK,CIRBP,MCL1,EIF4G2,PDE3B,USP36,TSC1,CHMP4A,SYNCRIP,GOLGA2,TAB2,HIPK2,LRPPRC,E2F1,PML,OGT,CHMP4B,CTSA,ROCK1,SNRNP70,TOB1,EGLN1,SVIP |
| 1.238e-03 | -6.69 | Formation of RNA Pol II elongation complex | REACTOME pathways | R-HSA-112382 | 65 | 21 | 10287 | 1696 |
CTDP1,POLR2I,POLR2G,POLR2L,POLR2K,ELOA,POLR2D,RTF1,EAF2,CDC73,POLR2A,IWS1,SUPT16H,GTF2F1,CCNK,PAF1,POLR2J,CTR9,TCEA1,GTF2H2,SSRP1 |
| 1.238e-03 | -6.69 | RNA Polymerase II Transcription Elongation | REACTOME pathways | R-HSA-75955 | 65 | 21 | 10287 | 1696 |
CTDP1,POLR2I,POLR2G,POLR2L,POLR2K,ELOA,POLR2D,RTF1,EAF2,CDC73,POLR2A,IWS1,SUPT16H,GTF2F1,CCNK,PAF1,POLR2J,CTR9,TCEA1,GTF2H2,SSRP1 |
| 1.239e-03 | -6.69 | regulation of nucleocytoplasmic transport | biological process | GO:0046822 | 113 | 30 | 17256 | 2622 |
TGFB1,TXN,PPP1R12A,DHX9,RAB23,NUP54,RANGAP1,NUTF2,PRKACA,MAPK14,PSEN1,RBM4,TRIM28,PARK7,IWS1,CDK5,MDM2,SP100,PIK3R2,PTPN11,GTSE1,NUP62,NUP153,MDFIC,MAVS,MAPK1,ZC3H3,NUP58,AAAS,CHP1 |
| 1.241e-03 | -6.69 | LRR domain binding | molecular function | GO:0030275 | 16 | 8 | 17224 | 2647 |
POLR2J,AATF,KRAS,PAWR,STK11,PMF1,ERC1,DAPK3 |
| 1.242e-03 | -6.69 | GSE557_WT_VS_I_AB_KO_DC_UP | MSigDB lists | GSE557_WT_VS_I_AB_KO_DC_UP | 180 | 43 | 17377 | 2626 |
CYLD,FAM208B,MANBA,WDR13,GNE,MCCC1,AP3M2,LAMTOR3,REEP5,HDDC2,CCDC28A,FLAD1,GOLM1,ASAP2,CLIC4,MTMR4,ERI3,SLC35C2,CNPY3,LPCAT1,SLC35A1,PREB,PDLIM2,METTL1,ABHD2,PTPN18,SEPT9,ETV3,SNX2,GLO1,MCL1,TMEM147,AZI2,STX16,NCDN,GPR137,MOSPD3,PFDN5,WDR11,STAT6,RWDD4,CCDC125,PDLIM5 |
| 1.242e-03 | -6.69 | GSE40274_FOXP3_VS_FOXP3_AND_EOS_TRANSDUCED_ACTIVATED_CD4_TCELL_DN | MSigDB lists | GSE40274_FOXP3_VS_FOXP3_AND_EOS_TRANSDUCED_ACTIVATED_CD4_TCELL_DN | 180 | 43 | 17377 | 2626 |
PKP4,H2AFZ,MRPS15,SRSF6,PTTG1,DBF4,NANS,S1PR2,NCAPG,IFT27,TCF19,CDKN2C,PA2G4,ZNF473,CCNA2,LPIN2,PPP6C,KIFAP3,SLC12A2,ARL5A,CFL1,ALDH9A1,GINS1,PHF10,RFC3,EMB,ERLIN1,KIAA0930,E2F3,CDCA2,EAF2,ZP3,ANLN,KIF11,OPTN,C1orf122,PRIM1,SLCO4A1,MTHFD2,POLE,KIF18B,CHEK2,RBBP4 |
| 1.242e-03 | -6.69 | GSE17974_0H_VS_12H_IN_VITRO_ACT_CD4_TCELL_DN | MSigDB lists | GSE17974_0H_VS_12H_IN_VITRO_ACT_CD4_TCELL_DN | 180 | 43 | 17377 | 2626 |
INTS2,SRM,MMACHC,IMMT,TP53RK,DHPS,CSNK2A1,SLC29A1,SDF2L1,TWF2,TMEM165,TCF19,FANCI,C14orf119,C12orf10,CLIC4,MCM5,BANF1,PPCDC,TTLL12,SPTSSA,CLN6,CNPY3,POLR2I,MLEC,MAPKAPK3,TMEM126B,ERLIN1,MRS2,C9orf40,ICMT,PSMB3,PAF1,ALG3,KEAP1,MTHFD2,ETS2,LTBP4,ACOX1,DNAJC17,BAZ1B,MLYCD,AAAS |
| 1.242e-03 | -6.69 | GSE15139_GMCSF_TREATED_VS_UNTREATED_NEUTROPHILS_UP | MSigDB lists | GSE15139_GMCSF_TREATED_VS_UNTREATED_NEUTROPHILS_UP | 180 | 43 | 17377 | 2626 |
RHOG,PTMS,NDUFV2,CYLD,PNISR,TRAF7,SUCLG1,C1orf112,FLOT1,CHIC2,SUMF1,PXMP2,IKBIP,MAP1LC3B,IFT27,RPAIN,PAIP2,MBD4,C14orf119,TMEM179B,MRPL50,RABGAP1L,FAM89B,RP2,RNASEH2A,CGGBP1,CAMK2G,ELOF1,TMEM160,ATP6V1G1,GINS1,CSRP1,CIC,NET1,ZMYM5,PRKRA,TMEM127,SEPT1,GOLGA7,WDR7,ST3GAL2,IGBP1,LTA4H |
| 1.242e-03 | -6.69 | GSE13493_DP_VS_CD4INTCD8POS_THYMOCYTE_UP | MSigDB lists | GSE13493_DP_VS_CD4INTCD8POS_THYMOCYTE_UP | 180 | 43 | 17377 | 2626 |
RMND5A,CORO7,KRBA1,RAB11B,AP3M2,CERK,SLC25A12,EZH1,SAFB2,PSEN1,FAM8A1,SLC25A37,TMCC3,KIF5B,RCSD1,ZNF335,DAPK1,AP1M1,TAP2,ZNF770,ILKAP,DCTN1,ATP6V1G1,LDHB,CELSR2,ZNF512,DENND4C,PPP1R21,MIER1,WBP1,GIGYF1,IRF5,PPP2CA,SERTAD2,ETS2,CLK3,DCK,GLG1,USP32,CNOT6,PSAP,PPP6R3,GLCCI1 |
| 1.242e-03 | -6.69 | GSE9988_LOW_LPS_VS_ANTI_TREM1_AND_LPS_MONOCYTE_UP | MSigDB lists | GSE9988_LOW_LPS_VS_ANTI_TREM1_AND_LPS_MONOCYTE_UP | 180 | 43 | 17377 | 2626 |
RHOG,GPR132,PLXNC1,UGP2,TRIP10,MOGS,CREBL2,BCL2L1,AP1B1,PSEN1,GNB2,CMTM6,MXD1,VAV1,VASP,CLIC4,PSMA6,ITGB8,LRRC8D,FJX1,FAM89B,ANP32A,CNN2,SRSF11,GTF3C6,BIRC3,TNFAIP3,ANKRD33B,PFKFB3,ARID1A,DNAJA1,STK17B,SERP1,PLEKHF2,XRCC5,TAB2,HNRNPR,STK38,OAZ2,ZNF436,SMG9,PARP10,ZC3HAV1 |
| 1.242e-03 | -6.69 | GSE21546_SAP1A_KO_VS_SAP1A_KO_AND_ELK1_KO_DP_THYMOCYTES_DN | MSigDB lists | GSE21546_SAP1A_KO_VS_SAP1A_KO_AND_ELK1_KO_DP_THYMOCYTES_DN | 180 | 43 | 17377 | 2626 |
USP7,HJURP,TCF3,PTTG1,MCCC1,CDCA8,TPX2,SMARCA4,ABHD14B,CNTROB,TTF1,ANKRD39,STRBP,HDAC7,RCSD1,CDC25B,GPD1L,RNF169,ELOF1,TERF2,CYTH1,TNFAIP3,PBXIP1,PBK,MKI67,RRM2,KRAS,RIT1,SYVN1,SYMPK,IRF5,SH3GLB1,ASF1B,XRCC5,SUPT16H,SH3BP5,CDCA4,COX7A2L,ACBD4,PPP2R2D,FAM72A,TMEM131,LRCH1 |
| 1.242e-03 | -6.69 | GSE36009_UNSTIM_VS_LPS_STIM_NLRP10_KO_DC_DN | MSigDB lists | GSE36009_UNSTIM_VS_LPS_STIM_NLRP10_KO_DC_DN | 180 | 43 | 17377 | 2626 |
MUT,SUCLG1,ARID2,SESTD1,CXXC1,ANKRD23,RPAIN,MRPL19,BCAT2,LYAR,PRKD3,NOL11,IARS,RINL,BDH1,EXOSC1,PTPN11,H2AFY,RPRD1B,CPNE1,FOXK1,MRPL12,ABHD11,BCLAF1,DNAJA1,ZFAND5,STK17B,MAK16,SPPL2B,RPA1,C1orf122,PFDN5,ZNF777,PEX5,MTHFD2,PPP2R5A,PML,SLC16A1,SMPD4,RRS1,EYA2,GPATCH4,RAB3IL1 |
| 1.242e-03 | -6.69 | GSE5589_WT_VS_IL10_KO_LPS_STIM_MACROPHAGE_45MIN_UP | MSigDB lists | GSE5589_WT_VS_IL10_KO_LPS_STIM_MACROPHAGE_45MIN_UP | 180 | 43 | 17377 | 2626 |
WASF2,SKA3,UBN1,EYA1,PIGQ,TKT,TPX2,ABHD14B,OIP5,DPYSL2,RCSD1,EFCAB11,CAPZA1,EI24,PRC1,SUCLG2,FNIP2,KIF22,SLC38A10,RBM3,MRPL48,RNF19A,SGCB,SLC12A2,GTF2H2,PDLIM2,NIPAL3,NOA1,RAD51AP1,CDCA2,RDH11,PRIM1,PRPS2,CEP55,H2AFX,CENPT,SMAD1,DNAJC30,GEN1,TERF1,ESPL1,POT1,SVIP |
| 1.244e-03 | -6.69 | MODULE_491 | MSigDB lists | MODULE_491 | 75 | 22 | 17377 | 2626 |
B3GALT6,BCL2L12,CHMP2A,RPLP2,ADAM10,TMX4,ACSL3,PARP4,MTMR6,ASAH1,UBE2V1,GYG1,MPG,ATP6V1B2,ATP1A1,FBXO7,PIKFYVE,METTL9,RNF14,HEXA,ABI1,RYBP |
| 1.244e-03 | -6.69 | BILD_CTNNB1_ONCOGENIC_SIGNATURE | MSigDB lists | BILD_CTNNB1_ONCOGENIC_SIGNATURE | 75 | 22 | 17377 | 2626 |
YTHDC1,ASH1L,PNISR,TNFAIP3,LUZP1,SRSF6,LRBA,SREK1,SECISBP2,RPL27A,CBX3,EPRS,SMC3,NEK1,RBM25,HIPK2,AXIN2,ZMAT3,ARL5A,TRIM14,DDX52,SRSF10 |
| 1.244e-03 | -6.69 | myxofibrosarcoma | COSMIC cancer mutations | myxofibrosarcoma | 20 | 9 | 17385 | 2587 |
GNAS,RB1,EWSR1,NRAS,NF1,PTEN,KRAS,FUS,HRAS |
| 1.244e-03 | -6.69 | soft_tissue-fibrous_tissue_and_uncertain_origin-fibrosarcoma-myxofibrosarcoma | COSMIC cancer mutations | soft_tissue-fibrous_tissue_and_uncertain_origin-fibrosarcoma-myxofibrosarcoma | 20 | 9 | 17385 | 2587 |
GNAS,RB1,EWSR1,NRAS,NF1,PTEN,KRAS,FUS,HRAS |
| 1.244e-03 | -6.69 | nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay | biological process | GO:0000288 | 70 | 21 | 17256 | 2622 |
SAMD4B,EXOSC6,POLR2D,EXOSC9,CNOT11,PARN,PATL1,PAIP1,TUT4,CNOT3,EDC3,CNOT9,EXOSC7,LSM6,EIF4A3,NT5C3B,EXOSC1,DCP1A,CNOT6,CNOT6L,PABPC1 |
| 1.246e-03 | -6.69 | ELM2_dom | interpro domains | IPR000949 | 13 | 7 | 18492 | 2768 |
RCOR1,MIER2,TRERF1,RCOR3,MTA1,MTA2,MIER1 |
| 1.252e-03 | -6.68 | ORF21 (thymidine kinase) | protein interactions | 4961484 | 37 | 14 | 17029 | 2761 |
GID8,RMND5A,NEK1,MKLN1,SNX18,LUC7L3,KCTD17,BCLAF1,THRAP3,XPNPEP3,CDC23,ARMC8,PAIP1,HTRA2 |
| 1.252e-03 | -6.68 | PPIF (peptidylprolyl isomerase F) | protein interactions | 10105 | 37 | 14 | 17029 | 2761 |
SUGP1,FKBP1A,GSTK1,NDUFAF2,RRBP1,NABP2,PTPN11,TPX2,RBMS1,RANGAP1,UBE4B,VDAC1,ATF2,GPX4 |
| 1.252e-03 | -6.68 | TOMM70 (translocase of outer mitochondrial membrane 70) | protein interactions | 9868 | 37 | 14 | 17029 | 2761 |
UNK,STAU1,TOMM20,DHX9,LAMTOR3,IRF3,MAVS,ADRB2,TOMM40,MCM2,RAB1A,SDHA,HNRNPM,TIMM50 |
| 1.252e-03 | -6.68 | PPT1 (palmitoyl-protein thioesterase 1) | protein interactions | 5538 | 37 | 14 | 17029 | 2761 |
SGSH,ATP1A1,PRDX5,VDAC2,LDHA,NIT2,ATP5F1B,ATP5F1A,TCOF1,TMEM9,PABPC4,PRDX1,SLC25A1,LDHB |
| 1.252e-03 | -6.68 | DNAJC8 (DnaJ heat shock protein family (Hsp40) member C8) | protein interactions | 22826 | 37 | 14 | 17029 | 2761 |
PA2G4,RAP1A,EWSR1,HUWE1,TPX2,ANXA5,XRCC3,SND1,CNTROB,PDLIM5,REEP5,SF3A2,APP,SRPK2 |
| 1.252e-03 | -6.68 | maintenance of cell number | biological process | GO:0098727 | 133 | 34 | 17256 | 2622 |
POLR2K,RAF1,NOTCH2,FOXO3,METTL3,SRRT,CDC73,TUT4,SMC3,MED10,METTL14,PELO,CTR9,MCPH1,STAT3,POLR2I,POLR2L,POLR2G,KLF10,ASPM,LDB1,POLR2D,LRP5,RTF1,ARID1A,SOX4,POLR2A,PAF1,EIF4ENIF1,PCM1,SMAD2,POLR2J,RBPJ,SMAD4 |
| 1.256e-03 | -6.68 | ECHS1 (enoyl-CoA hydratase, short chain 1) | protein interactions | 1892 | 66 | 21 | 17029 | 2761 |
PPIB,COX4I1,UBE2V1,SND1,PCBP1,ABHD14A,EPB41,TPD52L2,PA2G4,RAP1A,SYNCRIP,CBWD2,UCHL5,UBA5,DDA1,YWHAZ,TALDO1,AHCYL1,CAMK2G,CAPN1,ABCC1 |
| 1.257e-03 | -6.68 | CSR_EARLY_UP.V1_UP | MSigDB lists | CSR_EARLY_UP.V1_UP | 149 | 37 | 17377 | 2626 |
MAPRE1,REPS2,ACTR3,NUP54,KLF13,SMARCA4,PCSK7,MYO9B,ETS1,EIF4A3,TIMM23,FJX1,TFG,ZNF800,PPIF,SRP72,PHF20L1,KLF10,NET1,AMD1,GTPBP4,RNPS1,LRRC8A,UTP3,DNAJA1,EIF4H,CBFB,USP36,DOT1L,KPNA4,UAP1,NIP7,SLC16A1,SRSF3,EHD4,CCDC59,NMD3 |
| 1.259e-03 | -6.68 | MRPL46 (mitochondrial ribosomal protein L46) | protein interactions | 26589 | 45 | 16 | 17029 | 2761 |
MRPL50,MRPL9,CYLD,MRPL42,MRPL55,MRPL39,RPL6,ATP6V0A1,MRPL48,MRPL40,ATP5F1A,MCPH1,LUC7L,MRPL3,EIF3A,FUBP1 |
| 1.259e-03 | -6.68 | PRKAG1 (protein kinase AMP-activated non-catalytic subunit gamma 1) | protein interactions | 5571 | 45 | 16 | 17029 | 2761 |
PRKAB1,TRIM11,PRKAA1,BABAM1,CUTA,MCL1,DCLRE1C,MCM2,EIF3G,TARS,GLMP,WWP2,FAS,PA2G4,KEAP1,PHKG2 |
| 1.259e-03 | -6.68 | PSAP (prosaposin) | protein interactions | 5660 | 45 | 16 | 17029 | 2761 |
SUMO2,GBA,BRCA1,DNAJA1,THRAP3,SRSF5,USP48,SSR1,GTF2F1,SMAD2,SURF4,SNAP23,PSAP,MVP,COPS6,VPS29 |
| 1.269e-03 | -6.67 | SYF2 (SYF2 pre-mRNA splicing factor) | protein interactions | 25949 | 41 | 15 | 17029 | 2761 |
CDC40,XAB2,PPIE,BUD31,CRNKL1,YJU2,DHX8,GPATCH1,SNRPG,AQR,NKAPD1,APP,BTBD1,PRPF19,CDC5L |
| 1.269e-03 | -6.67 | DCD (dermcidin) | protein interactions | 117159 | 41 | 15 | 17029 | 2761 |
COX15,MDM2,CYLD,MCM5,AHSA1,SUMO2,CUL3,TARDBP,MCM2,VDAC1,CDK2,ARRB2,EYA2,CDC73,RAD51D |
| 1.269e-03 | -6.67 | LEF1 (lymphoid enhancer binding factor 1) | protein interactions | 51176 | 41 | 15 | 17029 | 2761 |
UBTF,KPNA1,SMAD2,HINT1,DPYSL2,KMT5A,SUMO2,E2F1,NARF,NFATC2,KPNA2,SMAD1,DAZAP2,RNF14,SMAD4 |
| 1.269e-03 | -6.67 | FOXH1 (forkhead box H1) | protein interactions | 8928 | 41 | 15 | 17029 | 2761 |
TCF12,PA2G4,LARS,SMAD2,IARS,DRAP1,BTAF1,TCF3,SMPD4,SOX4,DDX39A,SYMPK,MYEF2,SMAD4,SMC4 |
| 1.271e-03 | -6.67 | BENPORATH_ES_CORE_NINE_CORRELATED | MSigDB lists | BENPORATH_ES_CORE_NINE_CORRELATED | 99 | 27 | 17377 | 2626 |
FOXM1,ILF3,MYBL2,E2F3,PLAGL2,SMARCA4,WDHD1,HTATIP2,SOX4,CBFB,TAF2,MED8,RBL1,TFDP1,NFIL3,ETV6,STAT1,TBPL1,E2F1,CEBPG,YBX1,HMGB2,TFDP2,MYBL1,HDAC2,SAP30,SSRP1 |
| 1.271e-03 | -6.67 | WANG_ESOPHAGUS_CANCER_VS_NORMAL_DN | MSigDB lists | WANG_ESOPHAGUS_CANCER_VS_NORMAL_DN | 99 | 27 | 17377 | 2626 |
ATXN3,PLXNC1,MAPKAPK3,CAST,NSDHL,RAC1,SEPT8,RAB6A,DNAJB1,AP3S1,STK17B,ZER1,MOSPD3,GOLGA2,STK38,ACOX1,PPP4R1,CS,SLC27A4,PITPNA,SLC26A2,NCOA1,PGAM1,NRBP1,TSPAN5,GM2A,PDCD4 |
| 1.273e-03 | -6.67 | Small_GTPase | interpro domains | IPR001806 | 135 | 34 | 18492 | 2768 |
RHOG,RAB14,RHOA,NRAS,RHOBTB3,RAB11B,RAB7A,RHOC,RAC1,RAB23,KRAS,RIT1,RAB6A,RHOT1,RAB1A,RHOT2,RAB5B,IFT27,RAB11A,RAB22A,RAB2B,RHEB,RHOB,RAB18,RAB21,RAB8A,RAP1A,CDC42,RAB24,RALB,RAB35,RAB4A,HRAS,RHEBL1 |
| 1.273e-03 | -6.67 | GSE33425_CD161_INT_VS_NEG_CD8_TCELL_DN | MSigDB lists | GSE33425_CD161_INT_VS_NEG_CD8_TCELL_DN | 196 | 46 | 17377 | 2626 |
UBE2D3,UBL3,RAB14,MIF4GD,ADAM10,IVNS1ABP,SRGN,TOR3A,KLC1,CDC42SE2,EIF2AK4,GGA2,OAT,ETS1,LYN,CHD1,DNAJB9,GNS,RPN1,RAP1A,INPP5A,RNFT1,SLC44A1,EI24,SUCLG2,MDFIC,TIPARP,MTPN,DRAM2,MYO5A,POU2AF1,CYFIP1,FAM49B,SNX2,PSPC1,MCL1,DIDO1,LUC7L,HSPA4,AHNAK,TXNDC16,RAB24,SAFB,QRSL1,ROCK1,PSAP |
| 1.276e-03 | -6.66 | GO_CARBOHYDRATE_DERIVATIVE_BIOSYNTHETIC_PROCESS | MSigDB lists | GO_CARBOHYDRATE_DERIVATIVE_BIOSYNTHETIC_PROCESS | 542 | 108 | 17377 | 2626 |
PIGM,PPCS,GXYLT1,GNPNAT1,UGP2,AGRN,PRKCSH,PIGQ,UCK2,MOGS,UCK1,SIRT2,NANS,SLC35B2,EXT2,TET3,DUT,ADCY9,PPCDC,UPRT,RPN2,SLC26A2,LMAN1,SLC35C2,TIPARP,MGAT5,PDCL3,ABCC5,ADCY7,PGAP2,TMEM115,DPM1,ATP6V0A1,RRM2,GALNT7,AMDHD2,MCFD2,EDEM2,SERP1,ARF4,MAT2A,STOML2,ALG3,MAN2A2,DDOST,STT3A,OGT,CANT1,ST3GAL2,GALNT10,B4GALT3,CHPF2,B4GALT2,PIGN,GORASP1,B4GALT5,GNE,TRAK1,TKT,RRM1,SDC2,B4GALT1,SDF2L1,B4GALT4,PSEN1,TMEM165,POFUT1,MAN1A1,MAT2B,RPN1,C1GALT1,NUS1,GART,DAD1,ATIC,FUT8,PIGG,ATP6V0A2,OSTC,ST8SIA2,NAGPA,TGFB1,B3GALT6,AMPD2,TK1,GUK1,PIGT,TSTA3,MAN1B1,AMD1,PARP4,ADSL,DCTD,SYVN1,ADSS,GALNT2,UAP1,GOLGA2,MAGT1,DCK,PRPS2,TYW5,TBPL1,IMPDH1,NANP,HEXA,PARP10,PTDSS1 |
| 1.276e-03 | -6.66 | endosomal transport | biological process | GO:0016197 | 195 | 46 | 17256 | 2622 |
RAB14,SNX27,ANKRD27,CHMP2A,RAB11B,VTI1A,ZFYVE21,RAB6A,RAB11A,STAM,VPS25,RIC1,HEATR5B,SNX18,RAB35,TBC1D14,PIKFYVE,LMAN1,DCTN1,SNX8,GCC2,RHOBTB3,SNX2,DENND1B,RAB7A,CHMP2B,GOSR1,STX16,ERC1,PICALM,WAS,HGS,CHMP4A,TBC1D17,SURF4,RPS27A,GRIPAP1,VPS26B,AP1S1,CHMP4B,VPS4A,EHD4,CHMP7,ABCA1,VPS29,ALS2 |
| 1.276e-03 | -6.66 | GSE2770_IL12_AND_TGFB_VS_IL4_TREATED_ACT_CD4_TCELL_2H_DN | MSigDB lists | GSE2770_IL12_AND_TGFB_VS_IL4_TREATED_ACT_CD4_TCELL_2H_DN | 175 | 42 | 17377 | 2626 |
NDUFV2,CDC40,MPHOSPH8,BABAM1,TRAK1,ASAH1,RACGAP1,GMCL1,ATG2B,SNUPN,METTL14,TBC1D14,RAB4A,MRPL34,TPST1,BRD7,SLC27A4,BRI3,TCEA1,METTL9,CITED2,LPCAT1,TNRC18,TMEM14C,CDKN2AIP,PHF10,FAM172A,PGGT1B,JTB,FBXO9,NUP155,PPWD1,CDC23,SOCS7,C1orf122,RDH11,HIPK2,MAPK1,CD81,USF2,LTA4H,SAT2 |
| 1.276e-03 | -6.66 | GSE35825_UNTREATED_VS_IFNG_STIM_MACROPHAGE_DN | MSigDB lists | GSE35825_UNTREATED_VS_IFNG_STIM_MACROPHAGE_DN | 175 | 42 | 17377 | 2626 |
CERK,EPN1,SUMF1,RGS2,SEC16A,PIP4K2A,XPR1,GNS,TBC1D22A,SSBP3,ARHGEF1,CNPY4,UPRT,FAM76B,GLE1,TMEM8A,GNAI2,TPCN1,TERF2,VPS13B,SP3,PPP3CA,MAN1B1,NFATC2,NUTF2,UBE4B,TANC1,ASB13,SFXN5,MYO1F,OSBPL11,TTLL4,PRPS2,EXOC4,APPL2,NCOA1,WDR91,TFDP2,RTN3,SLC25A39,ATMIN,S100PBP |
| 1.277e-03 | -6.66 | GO_NUCLEAR_MEMBRANE | MSigDB lists | GO_NUCLEAR_MEMBRANE | 255 | 57 | 17377 | 2626 |
INTS2,DNAJC2,MRPS15,TOR1AIP1,TMEM109,TMEM97,NUP54,BRAP,BCL2L1,PSEN1,QSOX2,MRPL19,NUP205,LMNA,DTL,AHCTF1,NUP210,NDUFB4,INTS1,NUP107,EI24,TNPO2,TNPO3,YBX1,BCL2,NUP153,FAM76B,RBM15,TNRC18,SENP1,NUP85,RB1CC1,SIGMAR1,TEX10,GTPBP4,TOR1AIP2,NUP155,RANGAP1,NUTF2,MRPS14,MATR3,TMEM201,CBX3,LEMD2,PDCD6,PCM1,CERS6,OSBPL8,NRM,PML,LRPPRC,AEN,NUP62,SMAD1,AAAS,IPO4,ZC3HC1 |
| 1.281e-03 | -6.66 | GO_INTRA_GOLGI_VESICLE_MEDIATED_TRANSPORT | MSigDB lists | GO_INTRA_GOLGI_VESICLE_MEDIATED_TRANSPORT | 48 | 16 | 17377 | 2626 |
GCC2,SYS1,COPA,COPE,VTI1A,COG1,PACS1,RAB6A,GOSR1,COPG2,COPB2,OPTN,NAPG,GOLGA4,NSF,GCC1 |
| 1.281e-03 | -6.66 | MOLENAAR_TARGETS_OF_CCND1_AND_CDK4_DN | MSigDB lists | MOLENAAR_TARGETS_OF_CCND1_AND_CDK4_DN | 48 | 16 | 17377 | 2626 |
HJURP,TOR3A,CENPF,TPX2,CDCA8,CDC6,CDCA2,KIF2C,KIF11,CDKN2C,DTL,ZNF367,CEP55,CDCA7L,FAM83D,MYBL1 |
| 1.281e-03 | -6.66 | REACTOME_FORMATION_OF_THE_TERNARY_COMPLEX_AND_SUBSEQUENTLY_THE_43S_COMPLEX | MSigDB lists | REACTOME_FORMATION_OF_THE_TERNARY_COMPLEX_AND_SUBSEQUENTLY_THE_43S_COMPLEX | 48 | 16 | 17377 | 2626 |
RPS15,RPS2,EIF3D,RPS10,RPS24,RPS9,EIF3G,RPSA,EIF3H,EIF3A,EIF3K,EIF2S2,RPS27A,RPS14,FAU,RPS26 |
| 1.281e-03 | -6.66 | GO_RIBOSOMAL_LARGE_SUBUNIT_BIOGENESIS | MSigDB lists | GO_RIBOSOMAL_LARGE_SUBUNIT_BIOGENESIS | 48 | 16 | 17377 | 2626 |
PPAN,DDX28,RPL35,RPL6,RPL38,EBNA1BP2,BRIX1,MAK16,RPL11,RPL23A,NSA2,NOC2L,RPF2,MRPL11,RRS1,FTSJ3 |
| 1.282e-03 | -6.66 | SYNPO (synaptopodin) | protein interactions | 11346 | 154 | 40 | 17029 | 2761 |
MAPRE1,PPP1R12A,LUZP1,POC1A,RAF1,ACTR3,FLOT1,MYH9,TWF2,SEC16A,GNB2,CD59,ADD3,ARPC5,NAP1L4,CLTB,GNAI2,CSNK1G3,CFL1,EEF1D,CAMK2G,MYO5A,SPTAN1,PPP1R9B,PPP1R18,NCK1,WDR1,CAPZA2,PLEC,ANLN,TMEM201,DAPK3,GNAS,INF2,CORO1C,MYO18A,HMGB2,YWHAZ,ACTB,CDK2 |
| 1.292e-03 | -6.65 | proton-transporting V-type ATPase, V0 domain | cellular component | GO:0033179 | 10 | 6 | 18223 | 2701 |
ATP6V0A1,ATP6V0A2,ATP6V0C,ATP6V0B,ATP6V0D1,ATP6V0E1 |
| 1.292e-03 | -6.65 | transcription factor activity, protein binding | molecular function | GO:0000988 | 404 | 85 | 17224 | 2647 |
RORB,ZNF296,TRERF1,SMARCA4,RCOR3,SNAPC4,MXD1,RRN3,SP100,MTA1,JAZF1,NOC2L,CRY2,ATF2,MYBL1,CARM1,CCAR1,RLIM,RYBP,SAP30,CDC5L,POU2AF1,PBXIP1,ERF,EID1,DRAP1,RIOX2,WBP2,BRCA1,SOX4,TRIM28,TAF2,TONSL,HIPK2,ARNTL,NCOA1,BEND6,SMAD4,CBX4,POU3F2,NCOR2,MECP2,DHX9,ARID5A,MED13L,CTCF,MEF2A,PAWR,DNAJB1,MXD4,NOTCH2,THRAP3,FOXO3,TTF1,CDC73,WWP2,MED8,MED10,KMT5A,HDAC7,BRD7,CITED2,CREB1,MED22,CREG1,MTA2,ZMYND11,LDB1,MYBL2,RCOR1,RTF1,CBFA2T2,PFDN5,GPS2,ZHX1,PITX1,MED15,NFIL3,SIAH2,RUVBL2,NR2F2,YY1,TOB1,SGF29,N4BP2L2 |
| 1.292e-03 | -6.65 | Eukaryotic Translation Elongation | REACTOME pathways | R-HSA-156842 | 96 | 28 | 10287 | 1696 |
RPS15,RPL29,RPL35,RPS2,RPLP2,RPL8,RPS10,RPL6,RPL38,RPL15,RPS24,RPL27A,RPS9,RPSA,RPL11,RPL23A,RPL36,RPL37,RPL32,RPL17,RPS27A,RPS14,RPLP1,RPL19,FAU,RPS26,RPL22L1,EEF1D |
| 1.292e-03 | -6.65 | Eukaryotic Translation Termination | REACTOME pathways | R-HSA-72764 | 96 | 28 | 10287 | 1696 |
RPS15,RPL29,RPL35,RPS2,RPLP2,GSPT2,RPL8,RPS10,RPL6,RPL38,RPL15,RPS24,RPL27A,RPS9,RPSA,RPL11,RPL23A,RPL36,RPL37,RPL32,RPL17,RPS27A,RPS14,RPLP1,RPL19,FAU,RPS26,RPL22L1 |
| 1.295e-03 | -6.65 | diadenosine polyphosphate metabolic process | biological process | GO:0015959 | 7 | 5 | 17256 | 2622 |
KARS,NUDT11,MAPK1,NUDT4,NUDT3 |
| 1.295e-03 | -6.65 | SMAD protein complex assembly | biological process | GO:0007183 | 7 | 5 | 17256 | 2622 |
TGFB1,FKBP1A,SMAD2,SMAD1,SMAD4 |
| 1.297e-03 | -6.65 | double-strand break repair via homologous recombination | biological process | GO:0000724 | 89 | 25 | 17256 | 2622 |
RECQL,RAD51AP1,SMC6,BRCA1,BLM,WDR48,GINS4,RAD54B,RPA1,RPA2,RFWD3,RAD51C,PALB2,TONSL,NSMCE2,XRCC2,NABP2,NABP1,H2AFX,XRCC3,YY1,GEN1,SPIDR,RAD51D,POLQ |
| 1.297e-03 | -6.65 | ribonucleoside triphosphate biosynthetic process | biological process | GO:0009201 | 89 | 25 | 17256 | 2622 |
TGFB1,GALK1,COX5B,UCK2,LDHA,ATP6V0A1,UCK1,OGDH,ATP5F1B,ADPGK,PKM,ATP5MF,ATP5PF,STOML2,ATP5MC3,CTPS1,IMPDH1,ATP6V0A2,DHTKD1,CYC1,ATP5F1A,GPI,NIPSNAP2,PGAM1,PFKP |
| 1.298e-03 | -6.65 | unfolded protein binding | molecular function | GO:0051082 | 117 | 31 | 17224 | 2647 |
PPIB,HSPH1,CCT2,TOMM20,ST13,DNAJB2,ZFYVE21,SYVN1,DNAJA1,DNAJB1,CCT8,BBS12,HSPA1B,CHAF1A,PFDN5,HSPA4,SCAP,PFDN4,PDRG1,SIL1,RP2,RUVBL2,PTGES3,NAP1L4,PIKFYVE,CLN3,LMAN1,HTRA2,NUDC,CDC37,SRSF10 |
| 1.305e-03 | -6.64 | Fanconi anemia pathway | KEGG pathways | hsa03460 | 54 | 18 | 7161 | 1149 |
TELO2,ERCC1,POLK,RMI2,PMS2,TOP3A,BRCA1,BLM,FANCE,RMI1,FANCI,WDR48,RPA1,RPA2,FANCL,RAD51C,PALB2,FAAP100 |
| 1.305e-03 | -6.64 | Fanconi anemia pathway | KEGG pathways | ko03460 | 54 | 18 | 7161 | 1149 |
TELO2,ERCC1,POLK,RMI2,PMS2,TOP3A,BRCA1,BLM,FANCE,RMI1,FANCI,WDR48,RPA1,RPA2,FANCL,RAD51C,PALB2,FAAP100 |
| 1.308e-03 | -6.64 | V$USF_01 | MSigDB lists | V$USF_01 | 239 | 54 | 17377 | 2626 |
MAX,DNMT3A,PPCS,NDUFS1,ATXN3,ADAM10,SCYL1,SUMF1,GYG1,TAF6L,RLF,STMN1,COMMD8,RAPGEF6,GNB2,TFRC,SSR1,FAM192A,TFAP4,SMC3,ARPC5,ATIC,PRDM4,SLC26A2,DVL2,CCAR1,NUDC,RBM15B,PHF20L1,LONRF3,AATF,C16orf72,SIGMAR1,ILF3,TOPORS,UBE4B,MCM2,ODC1,PICALM,TSR2,EIF3A,RPA1,HMGN2,AKAP1,GNAS,TSC1,BRD2,RAB24,HPS5,MRPL27,RGL1,RBBP4,CLN3,RAB3IL1 |
| 1.309e-03 | -6.64 | DSRM | smart domains | SM00358 | 17 | 8 | 9493 | 1367 |
STAU1,STRBP,DGCR8,DUS2,ILF3,DHX9,NKRF,PRKRA |
| 1.309e-03 | -6.64 | ACIN1 (apoptotic chromatin condensation inducer 1) | protein interactions | 22985 | 116 | 32 | 17029 | 2761 |
WSB2,COX15,SARNP,TMEM184B,SUZ12,DHX9,CUL3,RNPS1,SMU1,CSNK2A1,THRAP3,SEPT7,LUC7L,RHOT2,SF3A2,PIP4K2A,DHX15,LMNA,DDX17,SUPT16H,SUB1,EIF4A3,SAFB,BANF1,FUT8,RRS1,BTBD10,NKAPD1,LUC7L2,IFI16,SSRP1,SRPK2 |
| 1.310e-03 | -6.64 | GO_PHOSPHOPROTEIN_PHOSPHATASE_ACTIVITY | MSigDB lists | GO_PHOSPHOPROTEIN_PHOSPHATASE_ACTIVITY | 170 | 41 | 17377 | 2626 |
CTDP1,PPP1R12A,EYA1,PPP1R15B,PTP4A3,CYCS,PPP3CB,DUSP22,EPM2A,UBLCP1,PTPN2,PPP1R3B,PDXP,PTEN,MTMR4,PPP4R1,PPP6C,PTPN11,CDC25B,CTDSP2,ILKAP,CAMK2G,TIMM50,PTPRK,PPP3CA,PTPN18,ACP2,MTMR6,STYXL1,PPP2CA,MTMR3,PTPRF,DUSP3,PPM1G,PPA2,PTPN7,PPP3R1,DUSP11,PTPDC1,PPP5C,EYA2 |
| 1.311e-03 | -6.64 | KEGG_RENAL_CELL_CARCINOMA | MSigDB lists | KEGG_RENAL_CELL_CARCINOMA | 66 | 20 | 17377 | 2626 |
TGFB1,NRAS,RBX1,VHL,RAF1,AKT2,RAC1,SLC2A1,KRAS,ETS1,MAP2K2,MAPK3,CRKL,RAP1A,CDC42,PIK3R2,PTPN11,MAPK1,HRAS,EGLN1 |
| 1.311e-03 | -6.64 | GO_REGULATION_OF_MEMBRANE_PERMEABILITY | MSigDB lists | GO_REGULATION_OF_MEMBRANE_PERMEABILITY | 66 | 20 | 17377 | 2626 |
BAK1,PPIF,DYNLL1,HEBP2,BCL2L1,RHOT1,SLC25A5,RHOT2,MOAP1,SIVA1,TFDP1,PPP3R1,E2F1,YWHAZ,BCL2,TP53BP2,ATF2,STAT3,YWHAH,EYA2 |
| 1.311e-03 | -6.64 | GO_GLYCOSPHINGOLIPID_METABOLIC_PROCESS | MSigDB lists | GO_GLYCOSPHINGOLIPID_METABOLIC_PROCESS | 66 | 20 | 17377 | 2626 |
GALC,HEXB,CERK,GBA,ASAH1,SUMF1,ARSK,NEU1,CREM,ITGB8,CTSA,GLTP,ST3GAL2,PSAP,SMPD4,ST8SIA2,CLN3,HEXA,CLN6,GM2A |
| 1.311e-03 | -6.64 | GO_REGULATION_OF_DNA_REPAIR | MSigDB lists | GO_REGULATION_OF_DNA_REPAIR | 66 | 20 | 17377 | 2626 |
TRIP12,FOXM1,EYA1,HELB,RAD51AP1,BABAM1,UBE2V1,BRCA1,TRIM28,RPA2,TERF2IP,PCNA,CEBPG,AXIN2,PML,H2AFX,OGG1,RNF169,POLQ,TERF2 |
| 1.314e-03 | -6.63 | GSE12198_NK_VS_NK_ACT_EXPANSION_SYSTEM_DERIVED_NK_CELL_DN | MSigDB lists | GSE12198_NK_VS_NK_ACT_EXPANSION_SYSTEM_DERIVED_NK_CELL_DN | 191 | 45 | 17377 | 2626 |
RAB14,RECQL,LUZP1,GNPDA1,ADAM10,HNRNPUL2,DCTN2,C16orf87,SLC2A1,HABP4,TMEM109,KLC1,PPP3CB,NCKAP1,B4GALT4,PSEN1,PSMD9,CDKN2C,INTS7,RALB,XRCC2,SUCLG2,ALDH18A1,UBE2M,KDELR1,ELOF1,NIPSNAP1,SEC61B,TMEM115,NASP,HARS,NQO2,LDHA,KRTCAP2,MCM2,ARPC1A,GLOD4,RBMX,LMBR1,CHEK2,RNF14,PDLIM5,RTN3,ANAPC4,TMEM33 |
| 1.314e-03 | -6.63 | GSE29618_MONOCYTE_VS_MDC_DAY7_FLU_VACCINE_DN | MSigDB lists | GSE29618_MONOCYTE_VS_MDC_DAY7_FLU_VACCINE_DN | 191 | 45 | 17377 | 2626 |
NDUFV2,RPS2,MRPL9,ST13,SLC2A1,LANCL1,BZW2,PIP4K2A,CD59,IRF4,SNRNP25,NDUFV1,MZT2A,NUP210,ATIC,EI24,RPL19,CNN2,FBL,PPA1,ACSL5,VOPP1,EIF3L,HMGN1,RPL35,NET1,RPS10,ESYT1,VDAC1,RPSA,RPL36,SH3BP5,PON2,CCDC86,PDLIM1,HINT1,CCDC6,ELMO1,TAB2,GOLGA8A,LIMK1,RBPJ,FAU,RUFY3,ACSF2 |
| 1.314e-03 | -6.63 | GSE26669_CTRL_VS_COSTIM_BLOCK_MLR_CD8_TCELL_UP | MSigDB lists | GSE26669_CTRL_VS_COSTIM_BLOCK_MLR_CD8_TCELL_UP | 191 | 45 | 17377 | 2626 |
ZNF207,GALK1,GNPNAT1,NDUFB6,MRPL39,DYNLL1,CUTA,TKT,EBNA1BP2,TCF19,RGS1,PNO1,MCTS1,ANKLE1,FARSA,UBXN2A,CCNA2,VMP1,ATIC,DUT,PPP6C,BCAP29,TAP2,C8orf59,MRPL48,LMAN1,MVP,MTX2,TACC3,KDELR1,EIF5A,ZNF524,HARS,RAD51AP1,TYW1,CKAP2L,CDCA2,TARS,ASF1B,NSA2,KIF18B,RBL1,CHCHD1,TFDP1,RNF114 |
| 1.314e-03 | -6.63 | GSE1925_CTRL_VS_24H_IFNG_STIM_IFNG_PRIMED_MACROPHAGE_DN | MSigDB lists | GSE1925_CTRL_VS_24H_IFNG_STIM_IFNG_PRIMED_MACROPHAGE_DN | 191 | 45 | 17377 | 2626 |
MBD1,GCLM,RECQL,PKP4,AGTRAP,CDCA3,KIF23,USP39,BLM,CDK11B,ANKIB1,NUDT19,BANF1,SUCLG2,BRI3,TMEM14C,S100A6,PCBP2,ACSL5,PLK1,PRIM2,GALC,ZMYND11,GTPBP4,ILF3,CRNKL1,WDHD1,MRPL16,EIF2A,GAR1,CYB5A,GEMIN5,MTHFD2,ATP6V1D,PDLIM1,TBL3,PRPS2,DBI,PML,CHMP4B,GAS2,YY1,RBBP4,BRWD3,SMNDC1 |
| 1.314e-03 | -6.63 | GSE24574_BCL6_HIGH_VS_LOW_TFH_CD4_TCELL_UP | MSigDB lists | GSE24574_BCL6_HIGH_VS_LOW_TFH_CD4_TCELL_UP | 191 | 45 | 17377 | 2626 |
PNISR,RPLP2,HLA-E,SRSF6,UBXN1,BTN3A1,RGS1,RPL11,CHKA,MOAP1,CD59,DLG5,ADD3,KDM2A,AKAP8,NSFL1C,JOSD1,ATG13,PIK3IP1,TIPARP,USP34,CYTH1,RPL29,DDX28,TNFAIP3,SEPT9,BTG2,KAT7,CIRBP,MATR3,EIF3A,RBM38,RPL37,MAGED2,PFDN5,HHEX,RPL32,RPS14,YWHAZ,DDX5,NCOA1,PPP6R2,EYA2,TERF1,TOB1 |
| 1.314e-03 | -6.63 | GSE3982_DC_VS_TH2_DN | MSigDB lists | GSE3982_DC_VS_TH2_DN | 191 | 45 | 17377 | 2626 |
HNRNPAB,MRPL42,MRPS15,MRPL39,PTTG1,CENPF,RRM1,RAB23,CTCF,KIF2C,ORC1,SNRPD3,FANCI,HDDC2,OIP5,CCNA2,CCP110,BCL2,TAGLN2,RFC3,NASP,TMEM39A,HARS,RPL6,HNRNPF,KIF15,SEPT8,DNAJC9,EXOSC9,ASF1B,GINS4,PSMC4,SUPT16H,GLOD4,XRCC5,RAD51C,ATAD2,BIRC5,TFDP1,FTSJ1,QRSL1,USP11,CCNB2,MRPL13,POLQ |
| 1.314e-03 | -6.63 | ATACTGT,MIR-144 | MSigDB lists | ATACTGT,MIR-144 | 191 | 45 | 17377 | 2626 |
UBE2D3,ZNF207,AGRN,ARID2,KIAA0232,TRIO,UBE4A,ETS1,PPP1R16B,TFRC,TFAP4,DLG5,CCNK,ZCCHC2,CAPZA1,AHCY,FAM76B,CHTOP,EIF5,SLC12A2,MTPN,HDHD2,ZNF800,SRSF10,CCT2,ELL2,USP42,HNRNPF,SREK1,ATXN1,MAP7D1,ARID1A,EIF4G2,EPB41,KPNA1,ZNF777,MAPK6,PPP3R1,FBXL3,NR2F2,GLCCI1,PURA,CPEB2,CBX4,ALS2 |
| 1.316e-03 | -6.63 | PUIFFE_INVASION_INHIBITED_BY_ASCITES_UP | MSigDB lists | PUIFFE_INVASION_INHIBITED_BY_ASCITES_UP | 80 | 23 | 17377 | 2626 |
GCLM,CCT2,CKLF,HJURP,TKT,CDCA8,TPX2,BCL2L1,PLEC,LYN,MAN2A2,FKBP1A,GART,ETS2,GATC,IMPAD1,RAB4A,SIAH2,KPNA2,NR2F2,LRRC59,HP1BP3,SAP30 |
| 1.316e-03 | -6.63 | GO_CHROMATIN_DNA_BINDING | MSigDB lists | GO_CHROMATIN_DNA_BINDING | 80 | 23 | 17377 | 2626 |
HMGN1,H2AFZ,HMGN5,HMGN4,SUZ12,MECP2,MTA2,WBP2,CTCF,SMARCA4,HMGN3,MBD3,FOXO3,HMGN2,MBD2,H2AFY,ACTB,RUVBL2,RBBP4,H3F3A,SMARCE1,STAT3,HDAC2 |
| 1.318e-03 | -6.63 | electron transport chain | biological process | GO:0022900 | 164 | 40 | 17256 | 2622 |
COX15,COX5B,NDUFA5,NDUFV2,NDUFS1,NDUFB6,NDUFAF2,UQCR10,MECP2,SLC25A12,NDUFA4,COX4I1,CYCS,GLRX3,SDHA,NDUFS7,NDUFS4,NDUFV1,NDUFA2,NDUFB4,AKR1B1,NDUFB9,NDUFS8,CYC1,NDUFA3,TSTA3,NQO2,NDUFA7,NDUFB1,TAZ,POLG2,CYB5A,SDHB,NDUFA11,COX7A2L,COX8A,COX5A,UQCRH,NDUFS5,IDH3B |
| 1.318e-03 | -6.63 | The oncogenic action of D-2-hydroxyglutarate in Hydroxygluaricaciduria | SMPDB pathways | SMP02359 | 29 | 12 | 992 | 167 |
SDHB,KDM2A,SUCLG1,IDH3A,MDH2,CS,SUCLG2,GLUD1,OGDH,IDH3B,SDHA,MPC1 |
| 1.320e-03 | -6.63 | metaplasia | COSMIC cancer mutations | metaplasia | 10 | 6 | 17385 | 2587 |
KRAS,STK11,PTEN,SF3B1,SMAD4,CDKN2A |
| 1.320e-03 | -6.63 | testis-germ_cell_tumour-teratoma | COSMIC cancer mutations | testis-germ_cell_tumour-teratoma | 10 | 6 | 17385 | 2587 |
KRAS,EWSR1,NRAS,VHL,HRAS,CDKN2A |
| 1.320e-03 | -6.63 | renal_cell_carcinoma_unclassified | COSMIC cancer mutations | renal_cell_carcinoma_unclassified | 10 | 6 | 17385 | 2587 |
FGFR3,KRAS,NRAS,VHL,HRAS,CDKN2A |
| 1.320e-03 | -6.63 | parathyroid-hyperplasia | COSMIC cancer mutations | parathyroid-hyperplasia | 10 | 6 | 17385 | 2587 |
GNAS,KRAS,NRAS,MEN1,CDC73,HRAS |
| 1.320e-03 | -6.63 | adrenal_gland-adrenal_gland-adrenal_cortical_adenoma-non_functioning | COSMIC cancer mutations | adrenal_gland-adrenal_gland-adrenal_cortical_adenoma-non_functioning | 10 | 6 | 17385 | 2587 |
GNAS,KRAS,ATP1A1,NRAS,MEN1,HRAS |
| 1.320e-03 | -6.63 | kidney-carcinoma-renal_cell_carcinoma_unclassified | COSMIC cancer mutations | kidney-carcinoma-renal_cell_carcinoma_unclassified | 10 | 6 | 17385 | 2587 |
FGFR3,KRAS,NRAS,VHL,HRAS,CDKN2A |
| 1.320e-03 | -6.63 | REACTOME_ADVANCED_GLYCOSYLATION_ENDPRODUCT_RECEPTOR_SIGNALING | MSigDB lists | REACTOME_ADVANCED_GLYCOSYLATION_ENDPRODUCT_RECEPTOR_SIGNALING | 13 | 7 | 17377 | 2626 |
CAPZA2,DDOST,MAPK1,PRKCSH,APP,MAPK3,CAPZA1 |
| 1.323e-03 | -6.63 | GO_NUCLEAR_CHROMOSOME_TELOMERIC_REGION | MSigDB lists | GO_NUCLEAR_CHROMOSOME_TELOMERIC_REGION | 124 | 32 | 17377 | 2626 |
ERCC1,THOC1,PRKDC,WDR82,DCLRE1C,ORC1,MEN1,MCM2,GAR1,CDC73,RPA1,XRCC5,WRNIP1,CBX3,TERF2IP,RPA2,PCNA,UPF1,SP100,MCM5,PML,MSH2,H2AFY,XRCC3,ORC3,H3F3A,PURA,TERF1,POT1,RAD51D,DDB1,TERF2 |
| 1.323e-03 | -6.63 | REACTOME_MEMBRANE_TRAFFICKING | MSigDB lists | REACTOME_MEMBRANE_TRAFFICKING | 124 | 32 | 17377 | 2626 |
CHMP2A,COPA,COPE,TGOLN2,ARF1,AP1B1,AP3S1,STAM,VPS25,TFRC,COPB2,GNS,SEC24C,AP1M1,DNM2,CLTB,PREB,FTL,SNX2,CHMP2B,AP4E1,PICALM,SEC31A,CHMP4A,HGS,RPS27A,SNAP23,AP1S1,CHMP4B,VPS4A,CHMP7,SNAPIN |
| 1.324e-03 | -6.63 | OCIAD1 (OCIA domain containing 1) | protein interactions | 54940 | 75 | 23 | 17029 | 2761 |
UNK,IMMT,TOMM20,TIMMDC1,FLOT1,NDUFA4,LANCL1,MTX1,TOMM40,NDUFB1,ATP5PF,PCBP1,ECH1,STOML2,SDHB,CHCHD3,GNAS,NDUFV1,RALB,NDUFS8,CLU,SLC25A1,TIMM50 |
| 1.324e-03 | -6.63 | CDC6 (cell division cycle 6) | protein interactions | 990 | 75 | 23 | 17029 | 2761 |
MCM10,KAT7,CDT1,E2F3,TOP3A,ORC1,CCNF,CCNB1,MCM2,GLMP,PON2,PCNA,CCNA2,RPS27A,HUWE1,E2F4,E2F1,CHEK2,ORC3,CDK2,E2F2,TERF1,CDKN2A |
| 1.324e-03 | -6.63 | UBA6 (ubiquitin like modifier activating enzyme 6) | protein interactions | 55236 | 75 | 23 | 17029 | 2761 |
UBE2D3,FYTTD1,PDCD6IP,NUP188,GNPDA1,PGGT1B,UBE2Z,UBE4B,USP48,FXR1,TWF2,H2AFV,RAB2B,RAD23A,ALDH3B1,EIF4A3,VPS26B,RAD23B,CTPS1,AHCYL1,HEXA,STRAP,PFKP |
| 1.324e-03 | -6.63 | WDR83 (WD repeat domain 83) | protein interactions | 84292 | 135 | 36 | 17029 | 2761 |
FGFR1OP,CDC40,XAB2,RAF1,LAMTOR3,CEP104,DPYSL2,BUD31,GPATCH1,ARHGEF2,RP2,ECD,AQR,PIKFYVE,PCBP2,CDC5L,RBM15B,PRPF19,CCT2,NET1,PPIE,CRNKL1,KRAS,CCT8,MAP2K2,GIGYF1,MAPK3,NEK1,PCM1,KEAP1,ZHX1,ODF2,YJU2,SNRPG,NKAPD1,MAPK1 |
| 1.324e-03 | -6.63 | MAP3K1 (mitogen-activated protein kinase kinase kinase 1) | protein interactions | 4214 | 135 | 36 | 17029 | 2761 |
UBE2D3,ATXN3,DNAJB2,RAF1,EPN1,GGA2,UBE2I,STAM,NPLOC4,RAD23A,UCHL5,DVL2,CDC37,RHOA,RAD51AP1,VHL,MAP4K4,UBE2V1,BRCA1,MCM2,ZFAND5,APPL1,MAPK3,HGS,RAD18,GRIPAP1,HIPK2,AXIN1,STK38,ODF2,CCDC69,FKBP5,MAPK1,ARRB2,RAB3IL1,RNF114 |
| 1.326e-03 | -6.63 | V$TEL2_Q6 | MSigDB lists | V$TEL2_Q6 | 223 | 51 | 17377 | 2626 |
TCF12,TRIM41,LIME1,ZNF768,CAST,AGPAT1,ARFIP2,CNTROB,INO80E,PRKACA,LYN,VPS25,CMTM6,FBXO22,TMEM69,ERH,CTSS,SHC1,KLHL20,RALB,RINL,SEC24C,CAPZA1,CTR9,OGG1,ZNF800,LYPLA2,CGGBP1,RLIM,ACSL5,SLC39A9,NASP,SNRPB,BTAF1,LYRM1,AMD1,RNPS1,DCLRE1C,SYVN1,SLC25A5,SMAP2,ARHGAP15,PALB2,TFE3,CORO1C,LPCAT4,APPL2,ARAP1,ARRB2,ZMAT3,NXT2 |
| 1.327e-03 | -6.62 | modification-dependent protein binding | molecular function | GO:0140030 | 132 | 34 | 17224 | 2647 |
DNAJC2,MPHOSPH8,KMT2E,KDM4A,SUZ12,UBXN1,SMARCA4,WDR5,LYN,CHD1,RAD23A,BABAM2,ABRAXAS2,RAD23B,BRD7,ZRANB1,RNF169,CARM1,MSH6,UBQLN4,BRD4,TNFAIP3,BAZ2A,ZMYND11,WDR81,OPTN,IDE,RAD18,BRD2,TAB2,BRD9,PARP10,SGF29,CBX4 |
| 1.328e-03 | -6.62 | human chr7q36.1 | chromosome location | human chr7q36.1 | 72 | 17 | 26185 | 2809 |
ZNF786,TMUB1,KRBA1,ABCF2,CUL1,SLC4A2,KMT2C,RHEB,CDK5,ZNF862,ZBED6CL,ZNF282,ZNF777,FASTK,XRCC2,ZNF746,CHPF2 |
| 1.333e-03 | -6.62 | GNF2_CDC27 | MSigDB lists | GNF2_CDC27 | 57 | 18 | 17377 | 2626 |
GCLM,RBX1,NUDT4,UROD,NARF,DNAJC9,EIF2AK1,XPO7,PSMD9,TFRC,RBM38,RAD23A,CDC27,TFDP1,FBXO7,DCAF11,MINPP1,HTRA2 |
| 1.333e-03 | -6.62 | GNF2_MYD88 | MSigDB lists | GNF2_MYD88 | 57 | 18 | 17377 | 2626 |
RHOA,RPS6KA1,SELPLG,MCL1,MAN2B1,RGS2,DAZAP2,LYN,CMTM6,HLA-B,RAB8A,TMEM127,WAS,ARPC5,STAT6,OSTF1,CORO1A,CNPY3 |
| 1.334e-03 | -6.62 | LLGL2 (LLGL2, scribble cell polarity complex component) | protein interactions | 3993 | 93 | 27 | 17029 | 2761 |
NEK7,GTPBP4,CSNK2A1,RCOR1,TOPORS,DNAJA1,THRAP3,DNAJB1,CCNB1,RCOR3,HMG20A,IWS1,UTP25,MKNK1,TRIM26,TIMM13,RAD18,PTEN,DDA1,KBTBD7,ALDH18A1,BRWD3,ATF2,NKAPD1,GCC1,ZC3H3,NUDC |
| 1.336e-03 | -6.62 | negative regulation of RNA metabolic process | biological process | GO:0051253 | 1299 | 236 | 17256 | 2622 |
RORB,TXN,ZNF496,MAX,H2AFZ,KDM4A,TSC22D3,TRIM11,SIRT2,UBE2I,MAPK14,CREM,CDK5,PA2G4,CIPC,GLIS2,ZNF639,JAZF1,ETV6,SRSF4,NOC2L,TRA2B,CRY2,FNIP2,SMARCE1,DNMT1,ARID4A,CCAR1,RYBP,SRSF10,PTPRK,PLK1,PLK3,SP3,DEAF1,KLF10,PBXIP1,NCK1,BAZ2A,GABPA,VHL,EHMT1,RIOX2,EZR,DDX20,AURKB,BRCA1,DOT1L,PAF1,BRMS1,HHEX,SMAD2,TONSL,RPS27A,RPS14,AXIN1,PRDX5,ZNF268,TFDP2,BEND6,RPS26,HDAC2,PDCD4,ZNF564,UBE2D3,PHB2,CENPF,DHX9,CTCF,MEF2A,THRAP3,DNAJB1,PSEN1,PARN,CDC73,LYAR,TFAP4,RB1,MLX,NFATC3,KLF16,MBD2,HDAC7,ZNF746,PHF14,CTR9,TIMELESS,MDFIC,YBX1,MCPH1,TNRC18,PABPC1,ZNF189,RBM42,ETV3,FOXK1,CREG1,ZMYND11,CIC,MTA2,LDB1,BCLAF1,RTF1,ARID1A,CBFA2T2,ZNF174,PHF6,XRCC5,PFDN5,SYNCRIP,ETS2,RBMX,QARS,NFIL3,SIAH2,ZFP90,RUVBL2,YY1,CDK2,TOB1,N4BP2L2,CDKN2A,MBD1,ZNF296,DNMT3A,MPHOSPH8,FOXM1,SUZ12,UBR2,MAGED1,WDTC1,SMARCA4,IRF3,DUSP22,RCOR3,MXD1,PAIP1,HNRNPA2B1,SPINDOC,SAP130,ZBTB21,MDM2,SHC1,SP100,MTA1,CDKN1B,TARDBP,ATF2,RBM15,STRAP,CGGBP1,RLIM,MOSPD1,SAP30,FAM172A,ZNF500,ERF,EID1,BTG2,DRAP1,PCGF6,CIRBP,CUL3,RNPS1,ATXN1,NFATC2,H2AFV,MBD3,TRIM28,CHCHD3,ZNF282,RBL1,MAFK,HIPK2,STAT6,ARNTL,H2AFX,DNAJC17,STAT1,BEND3,H3F3A,SMAD4,LRP8,CBX4,NCOR2,DEPDC1,DAP,SRSF6,MECP2,TCF3,ARID5A,PAWR,SECISBP2,NKRF,MXD4,HMG20A,FOXO3,MAD2L2,WWP2,PTPN2,SUV39H2,KMT5A,AXIN2,H2AFY,BRD7,CITED2,CREB1,STAT3,NCOA2,RBM15B,TSHZ1,TGFB1,PPP3CA,PSPC1,ZNF202,BTAF1,ILF3,RCOR1,ZP3,PRMT2,MEN1,CBX3,BIRC5,GPS2,ZHX1,PITX1,LRPPRC,E2F1,PML,HMGB2,DDX5,RBPJ,NR2F2,IGBP1,PURA,IFI16 |
| 1.337e-03 | -6.62 | regulation of ATP biosynthetic process | biological process | GO:2001169 | 75 | 22 | 17256 | 2622 |
NDC1,NUP188,RAE1,PRKAA1,NUP54,PFKFB3,NUP155,TAZ,NUP205,NUP210,TIGAR,NUP107,OGT,NUP62,NUP153,ECD,PGAM1,STAT3,NUP58,NUP85,AAAS,SEH1L |
| 1.337e-03 | -6.62 | Fc-gamma receptor signaling pathway | biological process | GO:0038094 | 75 | 22 | 17256 | 2622 |
WASF2,CYFIP1,NCK1,RAC1,ACTR3,VAV2,WIPF1,NCKAP1,CYFIP2,ARPC1A,LYN,MAPK3,VAV1,WAS,CDC42,ARPC5,ELMO1,LIMK1,PIK3R2,ACTB,MAPK1,ABI1 |
| 1.340e-03 | -6.62 | RWD | pfam domains | PF05773 | 10 | 6 | 17054 | 2545 |
EIF2AK4,RWDD1,RNF14,RNF25,DHX57,RWDD4 |
| 1.340e-03 | -6.61 | DNA recombination | biological process | GO:0006310 | 206 | 48 | 17256 | 2622 |
RECQL,NSMCE4A,UBR2,TCF3,RMI2,SMC6,TOP2B,INO80E,BLM,PAGR1,RMI1,RPAIN,WDR48,RFWD3,RPA2,UCHL5,XRCC2,MSH2,NABP2,NABP1,SPIDR,MSH6,ERCC1,MND1,EXOSC6,RAD51AP1,PRKDC,TOP3A,DCLRE1C,BRCA1,GINS4,RPA1,XRCC5,RAD54B,RAD51C,PALB2,TONSL,NSMCE2,H2AFX,XRCC3,HMGB2,RBPJ,RUVBL2,YY1,GEN1,XRCC4,RAD51D,POLQ |
| 1.342e-03 | -6.61 | heterochromatin | cellular component | GO:0000792 | 72 | 21 | 18223 | 2701 |
DNMT3A,H2AFZ,MPHOSPH8,BAZ2A,SUZ12,MECP2,TOP2B,SIRT2,MBD3,TRIM28,CBX3,PHC2,KMT5C,MBD2,PML,UHRF2,BAZ1B,H2AFY,BEND3,DNMT1,CDKN2A |
| 1.342e-03 | -6.61 | GSE32901_NAIVE_VS_TH17_ENRICHED_CD4_TCELL_DN | MSigDB lists | GSE32901_NAIVE_VS_TH17_ENRICHED_CD4_TCELL_DN | 165 | 40 | 17377 | 2626 |
UNK,ZBTB10,RHOC,TIA1,BCL2L1,AP3S1,CHD1,RGS1,PAIP1,DNAJB9,SLC25A36,CAPN2,RFWD3,PA2G4,CCDC50,MED10,LRRC8D,RABGAP1L,DAPK1,ALDH18A1,EIF5,LRSAM1,SMARCE1,ABI1,RLIM,MOSPD1,SRP72,PPP3CA,ARF4,PHF6,IDE,TMEM168,EXOC4,ATF6,MYO9A,H3F3A,GLCCI1,EYA2,FAF1,HDAC2 |
| 1.344e-03 | -6.61 | MYL6 (myosin light chain 6) | protein interactions | 4637 | 62 | 20 | 17029 | 2761 |
MOB4,EWSR1,SUZ12,RAC1,MYH9,CUL1,ATP5F1B,MCM2,ANLN,STMN1,MYL6B,DNAJB9,AHNAK,GRIPAP1,MYO18A,CYC1,AHCYL1,CDK2,ARRB2,CBX4 |
| 1.344e-03 | -6.61 | ADD1 (adducin 1) | protein interactions | 118 | 62 | 20 | 17029 | 2761 |
CDKN2AIP,HSPH1,TK1,MAPRE1,NUP54,SMARCA4,CAPZA2,MAP1LC3B,PRKACA,HMG20A,RPA1,RPA2,DST,INF2,ATP1A1,ADD3,ROCK1,IFI16,SPTAN1,GEMIN7 |
| 1.344e-03 | -6.61 | RAVER1 (ribonucleoprotein, PTB binding 1) | protein interactions | 125950 | 62 | 20 | 17029 | 2761 |
STAU1,GORASP2,AURKB,CAPZA2,CNOT11,EIF4H,SDHA,HAUS2,RPA1,RPA2,CDC16,GART,GADD45B,RTCB,FUS,TOB1,EYA2,TERF2,CDC5L,ABCC1 |
| 1.344e-03 | -6.61 | RAPGEF2 (Rap guanine nucleotide exchange factor 2) | protein interactions | 9693 | 62 | 20 | 17029 | 2761 |
MOB4,LAP3,TRMT6,XIAP,KCTD17,RACGAP1,UHRF1BP1,SND1,PLEC,KIF11,PRPSAP1,SCYL2,LMNA,KIF5B,RAP1A,COX5A,USP11,WDR91,ERI3,SSSCA1 |
| 1.346e-03 | -6.61 | MRPS27 (mitochondrial ribosomal protein S27) | protein interactions | 23107 | 84 | 25 | 17029 | 2761 |
NOL12,MRPS2,MRPS15,NOA1,MRPL12,RPL6,MRPS26,ILF3,CUL3,MRPS10,CUL1,AURKB,MRPS14,LUC7L,HAUS2,FERMT3,CAND1,DAP3,STRBP,GRSF1,ZNF746,TRMT10B,TARDBP,SMURF1,MRPL3 |
| 1.346e-03 | -6.61 | PTMA (prothymosin alpha) | protein interactions | 5757 | 84 | 25 | 17029 | 2761 |
PTMS,PSRC1,PHB2,PSMA1,NUTF2,CAPZA2,CCNB1,MCTS1,TERF2IP,CAPN2,PCNA,KEAP1,CCNA2,SYNCRIP,ATIC,NSFL1C,NUP62,KPNA2,TATDN1,CDK2,STAT3,YWHAH,TERF1,HDAC2,TERF2 |
| 1.346e-03 | -6.61 | TOLLIP (toll interacting protein) | protein interactions | 54472 | 84 | 25 | 17029 | 2761 |
SNX8,GGA1,WDYHV1,OXR1,MAGED1,LDB1,RAC1,WBP2,XIAP,ATXN1,GGA2,DAZAP2,MAPK14,TOLLIP,BIRC2,WRNIP1,CYHR1,SEPT1,ZHX1,SIAH1,RNF26,N4BP2,VPS29,CSTF1,RLIM |
| 1.346e-03 | -6.61 | DDB2 (damage specific DNA binding protein 2) | protein interactions | 1643 | 84 | 25 | 17029 | 2761 |
COPS8,CCT2,RBX1,KAT7,SUZ12,CDT1,TOPORS,DCLRE1C,PKM,CDK11A,CCT8,ISG15,PFDN5,PFDN4,PDRG1,BANF1,DDA1,XPA,E2F1,GTSE1,COPS7B,COPS6,USP53,SSSCA1,DDB1 |
| 1.349e-03 | -6.61 | response to reactive oxygen species | biological process | GO:0000302 | 185 | 44 | 17256 | 2622 |
NQO1,PPP1R15B,PRKAA1,PXMP2,BECN1,ETS1,PARK7,CFLAR,PDK2,PDCD10,CCNA2,MDM2,PCNA,DNM2,TRA2B,BCL2,PTPRK,PLK3,BAK1,PPIF,TNFAIP3,NET1,LDHA,MTR,RHOB,PRDX1,MAPK3,ANKZF1,CAT,KPNA4,PRDX3,GUCY1B1,STAT6,PRDX5,MPV17,STAT1,ADAM9,PKD2,MAP3K5,PPP5C,CDK2,MAPK1,HDAC2,EGLN1 |
| 1.355e-03 | -6.60 | GSE360_HIGH_VS_LOW_DOSE_B_MALAYI_DC_UP | MSigDB lists | GSE360_HIGH_VS_LOW_DOSE_B_MALAYI_DC_UP | 186 | 44 | 17377 | 2626 |
USP7,DNAJC2,ADD1,KLHL21,DCTN2,KIAA0232,TMED3,EPHX2,ITGB5,BIRC2,SLC25A36,TET3,TBC1D22A,DUT,KIF14,ADCY9,TRA2B,SS18L1,OSTF1,TCEA1,STRAP,FAM171A1,TXNL1,TK1,TMEM115,MKLN1,AATF,JTB,RABIF,GLO1,PRMT2,AP4E1,CLNS1A,TPD52L2,HGS,SERTAD2,GPS2,ATXN2L,SIAH2,MEGF9,DUSP11,PLOD3,PGAM1,CDKN2A |
| 1.355e-03 | -6.60 | GSE3982_MAC_VS_NEUTROPHIL_DN | MSigDB lists | GSE3982_MAC_VS_NEUTROPHIL_DN | 186 | 44 | 17377 | 2626 |
EWSR1,PLXNC1,GPBP1L1,EYA1,ACTR3,MON1B,BTN3A1,HAUS4,MYO9B,LYN,FOXO3,REPS1,GNB2,BIRC2,FBRS,NRF1,ZNF473,ARHGEF1,YIF1B,TAP2,CHTOP,LPCAT1,CTDSP2,PPP6R1,CDK12,ARID4A,EEF1D,ABCC5,PDLIM2,TRIM8,TNFAIP3,AATF,PPT1,KAT7,E2F3,MTMR12,STX16,SERP1,CSNK1G1,CABIN1,ACTB,PSAP,GALNT10,DEF6 |
| 1.355e-03 | -6.60 | GSE27786_NKCELL_VS_NKTCELL_UP | MSigDB lists | GSE27786_NKCELL_VS_NKTCELL_UP | 186 | 44 | 17377 | 2626 |
WASF2,TXN,TM9SF4,YTHDF3,SMC6,SUMF1,NOTCH2,ARF1,IKBIP,DUSP22,ITGB5,MAP1LC3B,TMEM179B,TNS3,RALB,ATG3,CAPZA1,ZNF326,SOCS6,PTPN11,ABCD1,TFG,NEK7,RAD51AP1,MAP4K3,MAP7D1,SOX4,ANLN,PRDX1,TFEB,DDX17,MKNK1,KPNA4,PPP2R5A,ORMDL2,GOLGA7,STT3A,OSBPL8,STK38,ACLY,YWHAZ,SCARB1,PSAP,CHID1 |
| 1.355e-03 | -6.60 | ALONSO_METASTASIS_UP | MSigDB lists | ALONSO_METASTASIS_UP | 186 | 44 | 17377 | 2626 |
BCCIP,MAPRE1,TMBIM4,CHCHD2,AKT1S1,EIF1B,RBM4,POLR3K,ATP6V0B,APLP2,MDM2,CLIC4,DAD1,PPP1R8,SRI,CYC1,EIF5,GTF2H2,ATP6V0D1,CDC5L,KLF10,ACSL3,RPS10,ADSL,GLO1,MAP4K3,VDAC1,ANLN,RAB1A,VKORC1,KIF11,CBFB,EIF3H,XRCC5,IDE,MFAP1,DCK,CHCHD1,PRDX5,COX8A,MDH1,ACADM,BTF3,SLC25A33 |
| 1.355e-03 | -6.60 | GSE8685_IL2_STARVED_VS_IL2_ACT_IL2_STARVED_CD4_TCELL_UP | MSigDB lists | GSE8685_IL2_STARVED_VS_IL2_ACT_IL2_STARVED_CD4_TCELL_UP | 186 | 44 | 17377 | 2626 |
OTUD5,NADSYN1,ANKRD13D,BABAM1,IL21R,RAPGEF6,GFM2,MIS12,NUP210,MED10,THADA,JAZF1,PPIL2,MEA1,TAP2,CNOT6L,F2R,EEF1D,VPS13B,NOL12,SEPT9,NCK1,RFXANK,NDUFA7,ESYT1,AZI2,PCGF1,HERPUD2,PEF1,DAPK3,SMAP2,POLR2A,FAS,TBC1D17,SH3GLB2,CANT1,ACBD4,SLAIN1,COPS6,SMURF1,RNF139,ABCA1,IPO4,DEF6 |
| 1.355e-03 | -6.60 | GSE22886_CD8_VS_CD4_NAIVE_TCELL_UP | MSigDB lists | GSE22886_CD8_VS_CD4_NAIVE_TCELL_UP | 186 | 44 | 17377 | 2626 |
GCLM,GLT8D1,GGNBP2,MUT,CKLF,MECP2,KIAA0232,SLC25A44,GGPS1,SYNRG,LYRM2,RAPGEF6,PARK7,CRKL,RPA2,SEC11A,PDCD10,MED8,UCHL5,ARL6IP1,ATP6V0A2,SLC26A2,HTRA2,DNAL4,NCK1,NEK7,DENND4C,ABCF2,PIP4K2C,SEPT7,PSMB9,ABCF1,RAB22A,SUPT16H,MKNK1,PDCD6,MID1IP1,ORMDL2,HPS5,WDR7,CAB39,TRIM32,USP11,TRAF5 |
| 1.355e-03 | -6.60 | GSE32164_RESTING_DIFFERENTIATED_VS_ALTERNATIVELY_ACT_M2_MACROPHAGE_UP | MSigDB lists | GSE32164_RESTING_DIFFERENTIATED_VS_ALTERNATIVELY_ACT_M2_MACROPHAGE_UP | 186 | 44 | 17377 | 2626 |
POLA2,CDT1,CDCA3,CDCA8,KIF23,RACGAP1,NCKAP1,S1PR2,STMN1,FZD6,SLC31A1,PCNA,GART,CCNA2,PRC1,MRPL54,KIF22,AHCY,PPA1,TK1,MAP4K4,EMP3,DNAJC9,RRM2,ITM2A,CDC6,NUSAP1,AURKB,USP22,ANLN,SOX4,MTR,PRIM1,MKNK1,PDLIM1,BIRC5,TULP3,MRPL27,KPNA2,CCNB2,RPS26,CDKN2A,TUBB,PTOV1 |
| 1.355e-03 | -6.60 | GSE2770_IL12_ACT_VS_ACT_CD4_TCELL_48H_UP | MSigDB lists | GSE2770_IL12_ACT_VS_ACT_CD4_TCELL_48H_UP | 186 | 44 | 17377 | 2626 |
IER2,NAT9,TMEM184B,SYS1,NDUFB6,FLOT1,VTI1A,UBE4A,SND1,FKBP2,PRPF39,MLX,SNUPN,SLC1A4,PELO,ZNF260,HADHB,ATP6V0A2,C8orf59,CITED2,SLC35C2,EEF1D,TMX1,RNF5,ETV3,CDC123,ATG9A,SIGMAR1,RDH10,EDF1,WBP1,EAF2,SLC50A1,APPL1,MOSPD3,PON2,SLCO4A1,GOLGA2,CTBS,PGRMC1,IMPDH1,FAM122A,SLC22A23,RTN3 |
| 1.355e-03 | -6.60 | GSE41867_DAY8_EFFECTOR_VS_DAY30_EXHAUSTED_CD8_TCELL_LCMV_CLONE13_DN | MSigDB lists | GSE41867_DAY8_EFFECTOR_VS_DAY30_EXHAUSTED_CD8_TCELL_LCMV_CLONE13_DN | 186 | 44 | 17377 | 2626 |
HIVEP3,TCF12,CTDP1,SYS1,EYA1,CCM2,RMI2,MYH9,PTP4A3,SUMF1,LCLAT1,UBLCP1,MBD4,NUDT19,FANCL,VASP,ADD3,WDR44,PPIL2,TANK,ZDHHC13,FBXW2,CISD2,CORO1A,CEP63,PIK3IP1,MYBL1,LPCAT1,NTPCR,ABHD2,MAPRE2,STK17B,TTC33,TFEB,RPL36,EIF3K,ANKRD10,SH3BP5,GNA12,GRIPAP1,PQBP1,RBMS1,CTSA,CABLES1 |
| 1.359e-03 | -6.60 | microtubule polymerization or depolymerization | biological process | GO:0031109 | 48 | 16 | 17256 | 2622 |
ZNF207,MZT1,TUBGCP5,KIF2C,STMN1,TUBGCP2,FBXO5,KIF2A,KIF18A,KIF18B,GOLGA2,KIF14,PIN1,CENPJ,NDE1,CSNK1D |
| 1.363e-03 | -6.60 | MIT_dom_sf | interpro domains | IPR036181 | 10 | 6 | 18492 | 2768 |
FBXO9,ULK3,VPS4A,RPS6KC1,SNX15,CAPN7 |
| 1.365e-03 | -6.60 | NEDD1 (neural precursor cell expressed, developmentally down-regulated 1) | protein interactions | 121441 | 140 | 37 | 17029 | 2761 |
RPS2,MZT1,TOMM20,MRPS26,NUP54,CDCA8,CNTROB,TUBGCP2,HNRNPA2B1,CEP104,MZT2A,CCP110,CENPJ,DCTN1,CCT2,HNRNPF,TUBGCP5,RPL38,UHRF1BP1,ATP5MF,HERPUD2,CCT8,RPS9,MAP3K4,DERL1,PCM1,HSPBP1,FBXO28,MAGT1,PFDN4,CHCHD1,ODF2,ACTB,SASS6,MZT2B,SSSCA1,TUBB |
| 1.365e-03 | -6.60 | deoxyribonucleoside monophosphate metabolic process | biological process | GO:0009162 | 13 | 7 | 17256 | 2622 |
DCTD,DNPH1,TK1,GUK1,DCK,DUT,HDDC2 |
| 1.365e-03 | -6.60 | regulation of autophagy of mitochondrion in response to mitochondrial depolarization | biological process | GO:1904923 | 13 | 7 | 17256 | 2622 |
ATP5IF1,SMURF1,HTRA2,OPTN,CDC37,GBA,MFN2 |
| 1.365e-03 | -6.60 | positive regulation of ubiquitin protein ligase activity | biological process | GO:1904668 | 13 | 7 | 17256 | 2622 |
PLK1,RAB1A,GOLGA2,UBE2C,PTEN,GORASP1,FBXO5 |
| 1.365e-03 | -6.60 | ribonucleoprotein complex disassembly | biological process | GO:0032988 | 13 | 7 | 17256 | 2622 |
KIF5B,KLC1,LIME1,GFM2,PELO,EIF2D,MCTS1 |
| 1.365e-03 | -6.60 | transferase activity, transferring one-carbon groups | molecular function | GO:0016741 | 225 | 52 | 17224 | 2647 |
ASH1L,DNMT3A,NOP2,KMT2E,CXXC1,SUZ12,NSD3,EZH1,WDR5,METTL3,IRF4,GART,KMT5C,SUV39H2,KMT5A,METTL14,ATIC,CMTR2,PRDM4,FAM86C1,FBL,DNMT1,MRM3,NSUN4,FTSJ3,CARM1,MRM2,METTL1,HEMK1,EHMT1,NSUN2,METTL5,METTL2A,ARMT1,WDR82,EDF1,ICMT,METTL22,KMT2C,PRMT2,MEN1,MTR,PRDM11,DOT1L,SETD3,CAMKMT,WDR4,FTSJ1,KMT2B,PRMT7,TRMT10B,GCSH |
| 1.368e-03 | -6.59 | cellular response to insulin stimulus | biological process | GO:0032869 | 154 | 38 | 17256 | 2622 |
WDTC1,ATP6V1B2,AP3S1,EEF2K,CFLAR,PTPN2,RAB8A,ATP6V0B,PDK2,USF1,SHC1,PTEN,PIK3R2,ATP6V0A2,ATP6V0D1,MYO5A,ATP6V1G1,PDPK1,CYFIP1,AKT2,DENND4C,PRKDC,ATP6V0A1,SRSF5,PKM,PDE3B,APPL1,SOCS7,EPRS,ATP6V1D,IDE,STAT1,ATP6V0C,ATP6V1C1,ATP6V0E1,C2CD5,CPEB2,SLC25A33 |
| 1.373e-03 | -6.59 | AMUNDSON_POOR_SURVIVAL_AFTER_GAMMA_RADIATION_2G | MSigDB lists | AMUNDSON_POOR_SURVIVAL_AFTER_GAMMA_RADIATION_2G | 160 | 39 | 17377 | 2626 |
ZNF207,USP7,PTMS,C9orf78,TMEM184B,GMFG,AGRN,SLC25A12,ORC1,MXD1,LMNA,DST,DLG5,INTS7,SSBP3,DUT,ADCY9,ZNF200,ANXA5,ANP32A,CORO1A,PPP6R1,TRIM14,MAPRE2,NASP,SELPLG,AMD1,ARHGAP15,SRSF1,SLC19A1,CSK,TPP2,PTPN7,ITGB1,PML,PRMT7,SNRPG,RBBP4,DEF6 |
| 1.374e-03 | -6.59 | regulation of cellular localization | biological process | GO:0060341 | 785 | 150 | 17256 | 2622 |
TXN,NF1,SEC16A,MAPK14,BECN1,RBM4,PARK7,PRNP,CALM2,CDK5,RAP1A,GLIS2,PIK3R2,CNPY4,SRI,AP2B1,NUP153,KCNAB2,PLK1,BAK1,PLK3,AKT2,EZR,LRP5,NUTF2,EPB41,IWS1,ITGB1,STK11,DVL1,ROCK1,VPS4A,TFDP2,OAZ1,C2CD5,NMD3,AAAS,NUMB,SVIP,UBE2D3,HSPH1,PPP1R12A,TM9SF4,PRKAA1,NKD2,DHX9,RAB23,CIB1,PPP3CB,PSEN1,LMNA,SPAG5,DDRGK1,FKBP1A,RB1,NUS1,RIMS3,BCL2,MDFIC,PREB,CYFIP1,ATP5IF1,GCC2,ACSL3,GOSR1,APPL1,MAP2K2,CCT8,PCM1,CSK,CDCA5,PPP3R1,NUP62,YWHAZ,RUFY3,RNF139,NUP58,RHOG,CYLD,NDUFAF2,RAB11B,DYNLL1,ANK3,BCL2L1,PRKACA,LYN,BCAP31,MIEF1,RAB21,MDM2,SP100,ATP2A2,RALB,PIN1,PARL,TP53BP2,MAVS,CORO1A,LMAN1,GPD1L,F2R,SPIDR,ZC3H3,TMBIM1,HTRA2,CHP1,CCT2,GOPC,KAT7,MAP4K4,DNAJA1,EDEM2,TRIM28,USP36,PPP2R5A,MAPK1,PARD3,CDT1,NUP54,HMGN3,RAB11A,SAPCD2,KIF5B,PDCD10,PTEN,HUWE1,PTPN11,H2AFY,GTSE1,ATG13,MYO5A,TGFB1,PDPK1,TCTEX1D2,RANGAP1,RHOT1,PICALM,SH3GLB1,MAPK3,NUCB1,PLAA,TFDP1,OAZ2,STX18,PML,E2F1,PKD2,PREPL,YWHAH,TERF1 |
| 1.376e-03 | -6.59 | PYEON_HPV_POSITIVE_TUMORS_UP | MSigDB lists | PYEON_HPV_POSITIVE_TUMORS_UP | 85 | 24 | 17377 | 2626 |
PNISR,NASP,CENPF,RMI2,KIF15,TIA1,CDKN2C,FANCL,DTL,ATAD2,INTS7,CENPJ,ZNF367,LY75,TARDBP,KNTC1,WDR76,RBBP4,GEN1,RBM15,FAM208A,CDKN2A,FUBP1,USP34 |
| 1.379e-03 | -6.59 | ELOB (elongin B) | protein interactions | 6923 | 107 | 30 | 17029 | 2761 |
LARS,CORO7,RBX1,VHL,ELOA,LAGE3,CUL3,ORC1,MCM2,ASB13,CBFB,CDC73,LRRC14,ZER1,SAP130,SEC31A,PFDN5,EPRS,MED8,CDC42,SOCS4,SOCS6,FEM1B,AP1S1,CTR9,RBM3,COPS6,USP11,NRBP1,ASB6 |
| 1.387e-03 | -6.58 | V$USF_Q6 | MSigDB lists | V$USF_Q6 | 245 | 55 | 17377 | 2626 |
MAX,DNMT3A,PPCS,NDUFS1,ATXN3,EWSR1,ANXA6,ADAM10,TSC22D3,SCYL1,GADD45G,SUMF1,GYG1,PRKACA,STMN1,SLC20A1,SYNRG,FAM192A,SLC38A5,ATG3,ATIC,JOSD1,FAM76B,HNRNPM,SOCS5,RBM15B,SNX8,AMPD2,PPP1R9B,HMGN1,NRAS,LONRF3,SNX2,C16orf72,MAPKAPK3,SELPLG,SUGP2,UBE4B,PICALM,HMGN2,AKAP1,SUPT16H,GNAS,BRD2,TMED10,HPS5,MPV17,SLC16A1,TCOF1,ATP6V1C1,CLN3,HEXA,PURA,RAB3IL1,SLC25A33 |
| 1.390e-03 | -6.58 | PID_ERBB2_ERBB3_PATHWAY | MSigDB lists | PID_ERBB2_ERBB3_PATHWAY | 44 | 15 | 17377 | 2626 |
NRAS,SHC1,CDC42,RAF1,PIK3R2,RAC1,PTPN11,KRAS,PPP3CB,PRKACA,STAT3,MAPK1,HRAS,MAP2K2,MAPK3 |
| 1.390e-03 | -6.58 | SHIPP_DLBCL_VS_FOLLICULAR_LYMPHOMA_UP | MSigDB lists | SHIPP_DLBCL_VS_FOLLICULAR_LYMPHOMA_UP | 44 | 15 | 17377 | 2626 |
MIF,MTHFD2,EXOSC7,ATIC,SNRPB,LDHA,KPNA2,SLC29A1,CCNB1,PGAM1,PSMC1,TFRC,GM2A,PFKP,PRDX1 |
| 1.393e-03 | -6.58 | GO_PRERIBOSOME_LARGE_SUBUNIT_PRECURSOR | MSigDB lists | GO_PRERIBOSOME_LARGE_SUBUNIT_PRECURSOR | 20 | 9 | 17377 | 2626 |
NSA2,PPAN,RPLP2,RPLP1,NOC2L,EBNA1BP2,RRS1,FTSJ3,MAK16 |
| 1.393e-03 | -6.58 | GO_GENETIC_IMPRINTING | MSigDB lists | GO_GENETIC_IMPRINTING | 20 | 9 | 17377 | 2626 |
GNAS,DNMT3A,MECP2,CTCF,PRMT7,KCNQ1,BRCA1,KDM1B,ARID4A |
| 1.396e-03 | -6.57 | GSE45739_UNSTIM_VS_ACD3_ACD28_STIM_NRAS_KO_CD4_TCELL_UP | MSigDB lists | GSE45739_UNSTIM_VS_ACD3_ACD28_STIM_NRAS_KO_CD4_TCELL_UP | 181 | 43 | 17377 | 2626 |
CYLD,PARP12,ST13,GORASP1,ANK3,AP3M2,LETMD1,HAUS4,LANCL1,CCNL2,UBQLN2,EPHX2,CUTC,PCYOX1L,GSTK1,INPP5A,GRSF1,IL6ST,LPIN2,HADHB,MDFIC,TARDBP,ORC3,TPCN1,NUP85,TACC3,LDHB,PHF10,DEAF1,NET1,TLK1,ADSL,PPWD1,DIDO1,STX16,ARHGAP15,NECAP2,DAP3,WDR59,IGBP1,DEF6,N4BP2L2,FUBP1 |
| 1.396e-03 | -6.57 | GSE11961_FOLLICULAR_BCELL_VS_PLASMA_CELL_DAY7_DN | MSigDB lists | GSE11961_FOLLICULAR_BCELL_VS_PLASMA_CELL_DAY7_DN | 181 | 43 | 17377 | 2626 |
TCF12,DDX47,ADAM10,RHOC,UROD,LAMTOR3,ABCB10,ABHD14B,PXMP2,SLC20A1,ETS1,KIAA1147,ANKRD28,CAPN2,SMC3,PPIG,TMEM9,KCNAB2,RBM15B,TRIM8,NASP,MKLN1,NCK1,TLK1,POLR3GL,WDHD1,RABIF,WDR82,BMS1,KRAS,RTF1,ASB13,PRPSAP1,PDE3B,RAD51C,PON2,MFAP1,CSNK1G1,GAS2,TCOF1,BRD9,ZC3HAV1,DEF6 |
| 1.396e-03 | -6.57 | GSE26351_UNSTIM_VS_BMP_PATHWAY_STIM_HEMATOPOIETIC_PROGENITORS_UP | MSigDB lists | GSE26351_UNSTIM_VS_BMP_PATHWAY_STIM_HEMATOPOIETIC_PROGENITORS_UP | 181 | 43 | 17377 | 2626 |
FGFR1OP,SEC61G,ACAP1,KIF2C,RPL23A,LYAR,SNRNP25,RAB21,CCNA2,ATG3,PPIG,BANF1,TIMELESS,TAGLN2,CORO1A,ZNRD1,PPA1,KCNAB2,ALDH9A1,ERMP1,PTPN18,NXT1,SEPT9,HMGN5,PPT1,TEX10,PSMB7,PSMA1,CADM1,RPS9,CYB5A,SDHB,HSPB11,PPP2R5A,CERS6,DCK,CHCHD1,STK38,RPS14,COX8A,LY75,MBOAT1,GPI |
| 1.396e-03 | -6.57 | GSE16450_IMMATURE_VS_MATURE_NEURON_CELL_LINE_12H_IFNA_STIM_DN | MSigDB lists | GSE16450_IMMATURE_VS_MATURE_NEURON_CELL_LINE_12H_IFNA_STIM_DN | 181 | 43 | 17377 | 2626 |
C1orf74,COX15,FGFR1OP,MRPL9,PIGN,CKLF,TMEM41B,NUP54,RAB6A,RGS2,FBXO22,CFLAR,CHKA,FBXO3,UBXN2A,CLIC4,IARS,RNFT1,ZDHHC13,RNF19A,POU2AF1,GTF3C6,POLK,COQ10B,NOL8,WDHD1,ATXN1,PDE3B,GOSR1,TMEM184C,UTP20,PON2,ATP6V1D,NEK1,ZNF330,GADD45B,TYW5,NAGLU,AEN,ATP6V0C,OSGEPL1,TATDN1,PDLIM5 |
| 1.396e-03 | -6.57 | GSE27786_BCELL_VS_CD4_TCELL_DN | MSigDB lists | GSE27786_BCELL_VS_CD4_TCELL_DN | 181 | 43 | 17377 | 2626 |
PTMS,TRIP12,ANXA6,HLA-E,TMX4,GLUD1,AGFG1,MAP1LC3B,FAM8A1,BIRC2,HMG20A,ANKRD39,RGS1,KIFC1,GOLM1,HUWE1,DPYSL2,ARHGEF1,PPP1R12C,CDC25B,UBE3B,RNF19A,TMEM8A,KCNAB2,PREB,ABCC5,TSHZ1,B3GALT6,CYFIP1,PPP1R18,TIMP2,LDB1,SEPT8,MTMR12,PRMT2,INF2,PFDN5,CDCA4,SETD3,ITGB1,MBOAT1,AKNA,HIGD2A |
| 1.396e-03 | -6.57 | GSE13411_NAIVE_BCELL_VS_PLASMA_CELL_DN | MSigDB lists | GSE13411_NAIVE_BCELL_VS_PLASMA_CELL_DN | 181 | 43 | 17377 | 2626 |
POLA2,PPIB,LIME1,TMEM184B,CDT1,GADD45G,LAGE3,TPX2,CDCA3,NENF,FKBP2,EPHX2,CD320,KIFC1,ANKRD26,SYNM,ZKSCAN1,RRBP1,LMAN1,PACS2,RYBP,METTL1,BAK1,TK1,TIMP2,AURKB,PKMYT1,CCNF,TOLLIP,ASF1B,NEU1,OPTN,SLC19A1,KIF18B,WNT5B,SEL1L,IMPDH1,WDR76,XRCC4,CCNB2,UBE2C,CHPF2,DYNC1LI2 |
| 1.396e-03 | -6.57 | GSE25123_ROSIGLITAZONE_VS_IL4_AND_ROSIGLITAZONE_STIM_MACROPHAGE_DAY10_UP | MSigDB lists | GSE25123_ROSIGLITAZONE_VS_IL4_AND_ROSIGLITAZONE_STIM_MACROPHAGE_DAY10_UP | 181 | 43 | 17377 | 2626 |
WSB2,BCCIP,PPCS,XAB2,GNE,EZH1,SNN,APOPT1,SPAG5,KIFC1,CAPN2,NFATC3,PDCD10,RIMS3,PELO,ECD,LMAN1,LRRC59,EEF1D,PDCL3,SNX25,POU2AF1,MLEC,TIMMDC1,NUDT4,VHL,NARF,MYBL2,EIF4H,EIF3H,RDH11,CDCA4,C1orf131,CCDC86,TFDP1,TCOF1,ATP6V1C1,PITRM1,RPS6KC1,SNX14,ZNF146,TUBB,FAM72A |
| 1.396e-03 | -6.57 | GSE24102_GRANULOCYSTIC_MDSC_VS_NEUTROPHIL_UP | MSigDB lists | GSE24102_GRANULOCYSTIC_MDSC_VS_NEUTROPHIL_UP | 181 | 43 | 17377 | 2626 |
IER2,ANKRD13D,GMFG,CIB1,NIPA2,TOP2B,ARGLU1,MAN2B1,SLC12A9,CPNE3,MFSD10,FBXO3,SAP130,NDUFV1,ADD3,CTNNBL1,AHSA1,XPA,ZDHHC13,MRPL34,TMEM8A,SAP30L,PTPRK,SRSF11,CPNE1,NTPCR,NXT1,FAM172A,NEK7,KAT7,EMB,OXR1,CIRBP,RABIF,DNAJC9,PCGF1,EPB41,GLOD4,ABHD5,TFDP1,NAA60,TSPAN5,SVIP |
| 1.396e-03 | -6.57 | GSE2770_IL4_ACT_VS_ACT_CD4_TCELL_6H_DN | MSigDB lists | GSE2770_IL4_ACT_VS_ACT_CD4_TCELL_6H_DN | 181 | 43 | 17377 | 2626 |
WSB2,HSPH1,DYNLL1,LAMTOR3,ZNF267,SLC35B2,ATP6V1B2,PSEN1,RMI1,CFLAR,VASP,PSMD1,MED8,TANK,TTC9C,TXLNA,ZNF200,TNPO3,ARHGEF2,TARDBP,ANAPC7,ABCC1,GPX4,METTL1,ADAM17,BIRC3,WDR1,ACSL3,CRNKL1,ATP6V0A1,DNAJA1,EML4,FADD,NEU1,NMT2,ACOX1,HPS5,MRPL27,PITPNA,PDXK,ATP6V1C1,PSMC1,ATP6V0E1 |
| 1.396e-03 | -6.57 | GSE20500_CTRL_VS_RARA_ANTAGONIST_TREATED_CD4_TCELL_DN | MSigDB lists | GSE20500_CTRL_VS_RARA_ANTAGONIST_TREATED_CD4_TCELL_DN | 181 | 43 | 17377 | 2626 |
CDC40,WDYHV1,RPS6KA1,PSMD9,SNAPC4,POLR3K,SSR1,BCAT2,FLAD1,SNRNP25,AHSA1,ATIC,PRC1,PDS5B,MAST2,RNASEH2A,CENPM,ALDH18A1,FAM86C1,SLC35A1,PREB,KDM3B,VOPP1,PLK1,DDX28,RHOA,POLR2G,KAT7,PIP4K2C,BORA,TXNL4A,PSMB9,CDK11A,GLOD4,RPA1,TSC1,TRIM26,BIRC5,PTER,RBPJ,PPP5C,ZNF45,PDSS2 |
| 1.403e-03 | -6.57 | GSE6269_HEALTHY_VS_FLU_INF_PBMC_DN | MSigDB lists | GSE6269_HEALTHY_VS_FLU_INF_PBMC_DN | 155 | 38 | 17377 | 2626 |
TM9SF4,RAB11B,DCAF15,STRN4,AGPAT1,AGPAT3,HLA-A,PHC2,CALM2,FKBP1A,ATP2A2,SSBP3,H2AFY,ABCD1,SCAMP4,TAGLN2,AHCYL1,GNAI2,KDELR1,TGFB1,FTL,WBP2,EMP3,ATP6V0A1,LY6E,ISG15,GNAS,NUCB1,PLD3,WAS,MID1IP1,MTHFD2,CCDC86,TFE3,PML,ACTB,RGL1,IFI16 |
| 1.403e-03 | -6.57 | GSE7509_UNSTIM_VS_FCGRIIB_STIM_MONOCYTE_DN | MSigDB lists | GSE7509_UNSTIM_VS_FCGRIIB_STIM_MONOCYTE_DN | 155 | 38 | 17377 | 2626 |
PRPF38B,MTX3,IVNS1ABP,ZBTB37,RAF1,TRAK1,PMS2,KLC1,CCNL2,ASXL2,RBM4,SNAPC4,RSAD1,FBRS,ZER1,NUP210,BRPF3,ARID4A,MICAL3,LUC7L2,CARS2,BAZ2A,BICD2,MACF1,KDM3A,TAZ,MAP3K4,TTLL4,APPL2,OGT,CABIN1,MBD6,PPP6R2,SNRNP70,BRWD3,DYNC1LI2,N4BP2L2,DDX42 |
| 1.403e-03 | -6.57 | GO_RESPONSE_TO_TOPOLOGICALLY_INCORRECT_PROTEIN | MSigDB lists | GO_RESPONSE_TO_TOPOLOGICALLY_INCORRECT_PROTEIN | 155 | 38 | 17377 | 2626 |
HSPH1,ATXN3,ADD1,SEC61G,CXXC1,DNAJB2,SDF2L1,DNAJB1,RHBDD1,LMNA,DNAJB9,SSR1,RNF121,SHC1,PDIA6,ATP6V0D1,CTDSP2,RNF5,PREB,DCTN1,BAK1,SEC61B,SYVN1,DNAJA1,HERPUD2,EDEM2,SERP1,MFN2,YIF1A,ANKZF1,SEC31A,DERL1,HSPA4,SEC61A1,TATDN2,ASNA1,ATF6,CLU |
| 1.412e-03 | -6.56 | negative regulation of phosphorylation | biological process | GO:0042326 | 472 | 96 | 17256 | 2622 |
ZBED3,FGFR1OP,ASH1L,GGNBP2,TSC2,FOXM1,NF1,DYNLL1,FAM129A,PPP1R15B,SIRT2,CCNB1,LYN,DUSP22,PARK7,PRNP,TERF2IP,CALM2,CDKN2C,PIN1,PIK3R2,SOCS6,CDKN1B,TARDBP,GPD1L,STRAP,CTDSP2,CHP1,PLK1,ANKLE2,SNX25,BAK1,PPIF,NCK1,PBK,GMFB,EZR,LRP5,DNAJA1,EIF3A,SOCS7,PPP2CA,HHEX,DNAJC10,PPP2R5A,CORO1C,STK38,GADD45B,SOCS4,DVL1,PPP5C,ARRB2,SMAD4,PDCD4,PARD3,HSPH1,GMFG,CIB1,AKT1S1,RGS2,PSEN1,VPS25,PTPN2,TFAP4,RB1,TIGAR,PTEN,FBXO7,DUS2,H2AFY,PIK3IP1,MVP,STAT3,SOCS5,PDPK1,TGFB1,RHOA,TNFAIP3,PRKDC,ZMYND11,GBA,PRKAR1B,MEN1,LEMD2,SH3BP5,MBIP,GPS2,DUSP3,CSK,PRDX3,QARS,NUP62,NR2F2,IGBP1,HIPK3,CDKN2A |
| 1.413e-03 | -6.56 | Peptide chain elongation | REACTOME pathways | R-HSA-156902 | 92 | 27 | 10287 | 1696 |
RPS15,RPL29,RPL35,RPS2,RPLP2,RPL8,RPS10,RPL6,RPL38,RPL15,RPS24,RPL27A,RPS9,RPSA,RPL11,RPL23A,RPL36,RPL37,RPL32,RPL17,RPS27A,RPS14,RPLP1,RPL19,FAU,RPS26,RPL22L1 |
| 1.415e-03 | -6.56 | GO_REGULATION_OF_CELLULAR_PH | MSigDB lists | GO_REGULATION_OF_CELLULAR_PH | 71 | 21 | 17377 | 2626 |
CLCN3,PPT1,RAB7A,SLC26A6,ATP6V0A1,SLC4A2,ATP6V1B2,TMEM165,ATP6V0B,CLIC4,ATP6V1D,ATP6V0A2,BCL2,ATP6V0C,SLC26A2,ATP6V1C1,CLN3,CLN6,ATP6V0E1,ATP6V0D1,ATP6V1G1 |
| 1.417e-03 | -6.56 | TGCTGCT,MIR-15A,MIR-16,MIR-15B,MIR-195,MIR-424,MIR-497 | MSigDB lists | TGCTGCT,MIR-15A,MIR-16,MIR-15B,MIR-195,MIR-424,MIR-497 | 561 | 111 | 17377 | 2626 |
MBD1,ZBTB10,LUZP1,TRIP10,TSC22D3,RAF1,WDTC1,KLHL18,UBE2Q1,GLUD1,SYNRG,APP,CRKL,CSDE1,CDC42,ZKSCAN1,SIAH1,MTMR4,ZCCHC2,RAD23B,PPP6C,SOCS6,BCAP29,PDIA6,SEH1L,CARM1,ABCC5,RYBP,BAZ2A,BTG2,TLK1,E2F3,UBE2V1,CADM1,DHX57,EIF3A,SUPT16H,MAP3K4,RAD51C,CDCA4,PEX5,MAP4,OGT,CAB39,PIEZO1,ZSWIM3,CHPT1,SMURF1,DCAF5,TSPAN5,CBX4,DYNC1LI2,PDCD4,TMEM33,POU3F2,MAPRE1,CDS2,SCOC,EYA1,VAV2,B4GALT1,KIF23,PPP3CB,EZH1,DCUN1D4,CCDC28A,KIF5B,TFAP4,NFATC3,PRDM4,AXIN2,COPS7B,BCL2,SLC12A2,LYPLA2,MOB4,YTHDC1,SRSF11,PHF20L1,C16orf72,SIGMAR1,USP42,CAMSAP1,RTF1,GORASP2,FAM133B,UBE4B,ARID1A,CAPZA2,ADRB2,SRSF5,LY6E,SFXN5,MAPK3,CACNB1,KPNA4,DUSP3,ZHX1,CCDC6,ACOX1,SETD3,CSNK1G1,TBPL1,PPP1R11,PITPNA,WIPI2,PPP6R3,YWHAH,PDLIM5,PURA,CPEB2 |
| 1.420e-03 | -6.56 | Adaptive Immune System | REACTOME pathways | R-HSA-1280218 | 810 | 165 | 10287 | 1696 |
MIB2,UBE2E2,TSC2,TRIM11,TAP1,CUL1,UBE2Z,UBE2Q1,KIF2C,FBXO22,CALM2,RAP1A,PSMD1,CDC42,PIK3R2,AP1M1,DNM2,AP2B1,FBXW2,KIF22,ASB6,MLST8,ORAI2,NRAS,NCK1,RBX1,AKT2,VHL,KIF15,UBE2V1,CCNF,TRIM4,WAS,RPS27A,PSMD8,TPP2,ITGB1,KLHL42,FBXL3,PSMC1,UBE2D3,SEC61G,HLA-E,KLC1,KIF23,RACGAP1,PSMD9,ITGB5,VASP,UBE2Q2,MEX3C,KLHL5,ZNRF2,FBXO7,ORAI1,FBXL7,KIFAP3,UBE3C,LRSAM1,PIP4K2C,PSMA1,KRAS,ICAM2,PSMB3,PSMC4,SEC31A,CDC27,CSK,SNAP23,SIAH2,CTSA,YWHAZ,RNF14,RNF114,KCTD7,TRIM41,TRAF7,RAF1,DYNLL1,UBR2,RAC1,AP1B1,LYN,PRKACA,VAV1,MDM2,PSMA6,SHC1,SIAH1,UBA5,CDKN1B,TAP2,ANAPC7,RNF19A,AHCYL1,RLIM,DCTN1,SEC61B,PSMA8,RAB7A,RNF25,CUL3,PSMB7,CDC23,ASB13,PSMB9,BTBD1,PPP2CA,KIF2A,CDC16,PPP2R5A,SEC61A1,TAB2,PSMD3,AP1S1,TRIM32,SMURF1,MAPK1,AP2S1,DYNC1LI2,KIF3B,TRIP12,KLHL21,DCTN2,AGO2,BTN3A1,UBE4A,ARF1,AKT1S1,FOXO3,PIP4K2A,HLA-A,PIP5K1C,KIF5B,HERC3,PSMD2,FGFR3,CTSS,KLHL20,PTEN,HUWE1,SEC24C,PTPN11,LTN1,UBE3B,CREB1,MAP3K14,FBXL19,UBE2M,PDPK1,FBXO9,ANAPC2,KIF11,MAPK3,CTSL,HLA-B,FBXO21,FBXO41,KIF18A,KEAP1,KBTBD7,UBE2C,CD81,HRAS,ANAPC4 |
| 1.427e-03 | -6.55 | RUTELLA_RESPONSE_TO_HGF_UP | MSigDB lists | RUTELLA_RESPONSE_TO_HGF_UP | 395 | 82 | 17377 | 2626 |
PDCD6IP,TXN,NQO1,TRIP10,SUZ12,FAM129A,HEXB,TMEM97,ENSA,CREBL2,TBC1D13,NIT2,PLXNA1,BCAP31,ZNF804A,TNFAIP8,GOT2,IL6ST,GRSF1,ATP13A3,AKR1B1,MOB1A,TFG,GM2A,PPIF,METTL1,TIMP2,BIRC3,ATP6V0A1,PSMG1,OPTN,TMEM184C,JAK1,RBM47,CERS6,STAT1,PDXK,CHPF2,ATP6V0E1,HDAC2,GCLM,CDS2,PPP1R12A,TM9SF4,B4GALT5,TCF3,GADD45G,SDC2,ASAH1,SLC35B1,IL21R,TFRC,CFLAR,GNS,CD59,IRF4,TNS3,SLC31A1,SLC1A4,DAD1,MCM5,TPST1,ANXA5,MTX2,CSRP1,CREG1,ACSL3,CYB5A,PRDX1,TFEB,RDH11,SCARB2,GNA12,CTBS,OAZ2,LY75,ACAT1,MDH1,RGL1,ATP6V1C1,PLOD3,CD81 |
| 1.430e-03 | -6.55 | CCDC137 (coiled-coil domain containing 137) | protein interactions | 339230 | 26 | 11 | 17029 | 2761 |
NOL12,SYNCRIP,DGCR8,RPS14,RBM34,RPL8,ATP5MF,SNRNP70,GPATCH4,IFI16,TERF2 |
| 1.430e-03 | -6.55 | Dennd6a (DENN/MADD domain containing 6A) | protein interactions | 211922 | 26 | 11 | 17029 | 2761 |
YTHDC1,CYTH1,MKNK1,PDCD6,RB1CC1,ANK3,OGT,SLC27A4,BCLAF1,RPS6KC1,SRRT |
| 1.430e-03 | -6.55 | ZCCHC7 (zinc finger CCHC-type containing 7) | protein interactions | 84186 | 26 | 11 | 17029 | 2761 |
NOL12,PPAN,EIF2S2,ZKSCAN1,DGCR8,ZNHIT6,SUMO2,HDGFL2,UBE2I,LYN,FAM208A |
| 1.430e-03 | -6.55 | NEMF (nuclear export mediator factor) | protein interactions | 9147 | 26 | 11 | 17029 | 2761 |
ZNF786,SEC61B,EIF2S2,COX5A,LTN1,XRCC3,STK11,HAUS2,DHX15,IFI16,RPL11 |
| 1.430e-03 | -6.55 | Mcm3 (minichromosome maintenance complex component 3) | protein interactions | 17215 | 26 | 11 | 17029 | 2761 |
GCC2,DGCR8,ELL2,MCM5,PMS2,OGT,MCM2,MCMBP,GAR1,TRIM28,SPAG5 |
| 1.430e-03 | -6.55 | eye-retina-retinoblastoma | COSMIC cancer mutations | eye-retina-retinoblastoma | 28 | 11 | 17385 | 2587 |
RB1,EWSR1,LHX8,NRAS,PTEN,SF3B1,KRAS,DMWD,H3F3A,HRAS,STOML2 |
| 1.430e-03 | -6.55 | retinoblastoma | COSMIC cancer mutations | retinoblastoma | 28 | 11 | 17385 | 2587 |
RB1,EWSR1,LHX8,NRAS,PTEN,SF3B1,KRAS,DMWD,H3F3A,HRAS,STOML2 |
| 1.431e-03 | -6.55 | CPNE2 (copine 2) | protein interactions | 221184 | 58 | 19 | 17029 | 2761 |
POLR2I,NUP54,POLR2D,MCM2,POLR2A,EIF3H,EIF3A,TERF2IP,AFDN,NEK1,PDCD6,POLR2J,NOC2L,TXLNA,NUP62,ACTB,PPP5C,UBE2M,NUP58 |
| 1.431e-03 | -6.55 | TOPBP1 (DNA topoisomerase II binding protein 1) | protein interactions | 11073 | 58 | 19 | 17029 | 2761 |
GINS1,PLK1,ERCC1,PMS2,SMARCA4,TOP2B,BRCA1,BLM,RMI1,RPA1,TFAP4,POLE,E2F1,PML,ACAT1,DTD1,MSH6,DDB1,SMC4 |
| 1.431e-03 | -6.55 | GPN3 (GPN-loop GTPase 3) | protein interactions | 51184 | 58 | 19 | 17029 | 2761 |
POLR2I,RPRD1A,POLR2G,POLR2L,ASPM,POLR2D,SMC6,TGOLN2,BRCA1,POLR3K,POLR2A,WDR48,WWP2,FAS,CXXC4,CD3EAP,POLR1B,RPRD1B,ASB6 |
| 1.435e-03 | -6.55 | GO_REGULATION_OF_ATTACHMENT_OF_SPINDLE_MICROTUBULES_TO_KINETOCHORE | MSigDB lists | GO_REGULATION_OF_ATTACHMENT_OF_SPINDLE_MICROTUBULES_TO_KINETOCHORE | 10 | 6 | 17377 | 2626 |
RACGAP1,SIRT2,CCNB1,CDC42,BECN1,SPAG5 |
| 1.435e-03 | -6.55 | GO_REGULATION_BY_VIRUS_OF_VIRAL_PROTEIN_LEVELS_IN_HOST_CELL | MSigDB lists | GO_REGULATION_BY_VIRUS_OF_VIRAL_PROTEIN_LEVELS_IN_HOST_CELL | 10 | 6 | 17377 | 2626 |
DERL1,TAP2,STAU1,DDB1,STAT1,TAP1 |
| 1.435e-03 | -6.55 | GO_DERLIN_1_RETROTRANSLOCATION_COMPLEX | MSigDB lists | GO_DERLIN_1_RETROTRANSLOCATION_COMPLEX | 10 | 6 | 17377 | 2626 |
DERL1,SYVN1,RNF139,RNF5,SEL1L,SVIP |
| 1.436e-03 | -6.55 | EIF3I (eukaryotic translation initiation factor 3 subunit I) | protein interactions | 8668 | 98 | 28 | 17029 | 2761 |
TGFB1,EIF3L,CYLD,EXOSC6,TRIP12,SRSF6,EIF3D,CUL3,BRCA1,EIF1B,KIF11,EIF3G,EIF3H,EIF3A,EIF3K,LYAR,SUB1,HUWE1,ZNF746,TRA2B,YBX1,TARDBP,LMAN1,EIF5,CDK2,CD81,TMED2,PDCD4 |
| 1.436e-03 | -6.55 | GSE42021_TREG_PLN_VS_CD24LO_TREG_THYMUS_UP | MSigDB lists | GSE42021_TREG_PLN_VS_CD24LO_TREG_THYMUS_UP | 176 | 42 | 17377 | 2626 |
ST13,NF1,TRIP10,TMX4,OLA1,CERK,ASAH1,KIF2C,PMF1,WRB,PABPC4,RPL11,ANKRD26,CCNK,EIF2S2,PTEN,LRRC8D,LRRC59,IFT46,PPP3CA,DCAF6,TMEM126B,OXR1,GMFB,ABHD11,DIDO1,STYXL1,ODC1,RAB5B,AP4E1,RAB22A,RXRB,MYO1F,AMZ2,VEZF1,AHNAK,JAK1,GOLGA2,OSBPL8,IARS2,IMPDH1,IGBP1 |
| 1.436e-03 | -6.55 | GSE2770_TGFB_AND_IL4_ACT_VS_ACT_CD4_TCELL_6H_DN | MSigDB lists | GSE2770_TGFB_AND_IL4_ACT_VS_ACT_CD4_TCELL_6H_DN | 176 | 42 | 17377 | 2626 |
INTS2,LUZP1,THOC1,FAM76A,EBNA1BP2,ZNF267,MAPK14,SEC16A,RPAIN,MAD2L2,PIP5K1C,CEP104,HOMER1,STRBP,IMPAD1,SIVA1,COPS7B,TTC3,AHCYL1,RNF26,POC5,TTPAL,TRAPPC9,RPRD1A,RAB7A,BTAF1,MRS2,GTPBP4,PIP4K2C,MRPS10,API5,RFC2,TFEB,RPL36,TRIM4,TMEM127,CAPN7,ADAM9,WIPI2,MYO9A,ATP6V0E1,SNAPIN |
| 1.436e-03 | -6.55 | GSE18893_TCONV_VS_TREG_24H_TNF_STIM_DN | MSigDB lists | GSE18893_TCONV_VS_TREG_24H_TNF_STIM_DN | 176 | 42 | 17377 | 2626 |
HIVEP3,LZTR1,THOC1,MRPS15,MRPL39,CUTA,TOP2B,HCFC1R1,MAPK14,MIEN1,CMTM6,CCDC28A,CD320,ANKRD26,GTPBP3,HOMER1,SLC44A1,NSFL1C,AKR1B1,CNN2,OSTC,MOB1A,SMC4,ADCY7,GUK1,GALC,ATP2C1,ZBED5,NLN,ZMYM3,ZNF862,ZNF317,TIMM13,PDRG1,CHCHD1,DCAF11,RWDD4,PPP1R11,TRIM32,SNRPG,HEXA,USP53 |
| 1.436e-03 | -6.55 | GSE18804_SPLEEN_MACROPHAGE_VS_BRAIN_TUMORAL_MACROPHAGE_DN | MSigDB lists | GSE18804_SPLEEN_MACROPHAGE_VS_BRAIN_TUMORAL_MACROPHAGE_DN | 176 | 42 | 17377 | 2626 |
USP7,HSPH1,CDC40,TSC22D3,CDT1,C16orf87,MON1B,CTCF,COX4I1,DNAJB1,OAT,MAP1LC3B,POLR3K,HDDC2,SSR1,TERF2IP,SNRNP25,CCP110,SIAH1,TRMU,NDUFB9,N4BP2,DDX28,PHF20L1,FAM49B,HSDL1,BOLA1,PRPF3,VKORC1,CBFB,ANKRD46,EIF3H,ZNF700,NSMCE2,ADAM9,ZDHHC7,PRMT7,MRPL13,TERF1,RNF139,ATMIN,DYNC1LI2 |
| 1.437e-03 | -6.55 | LSM8 (LSM8 homolog, U6 small nuclear RNA associated) | protein interactions | 51691 | 71 | 22 | 17029 | 2761 |
SNRNP200,EXOSC6,MTA2,SNRPB,DBF4,OLA1,SMU1,USP39,PRPF3,FERMT3,UPF1,RPL32,HNRNPR,LSM6,EFTUD2,MAP4,DCP1A,PDCD2,PRPF4,MRPL48,TALDO1,CDKN2A |
| 1.437e-03 | -6.55 | SIAH2 (siah E3 ubiquitin protein ligase 2) | protein interactions | 6478 | 71 | 22 | 17029 | 2761 |
UBE2D3,POU2AF1,PPP1R12A,TPX2,EAF2,MCM2,UBE2I,AKAP1,VAV1,SIAH1,HIPK2,PML,SIAH2,PIAS2,AFF1,CHEK2,TP53BP2,STAT3,HIPK3,EEF1D,EGLN1,USP13 |
| 1.437e-03 | -6.55 | HTRA2 (HtrA serine peptidase 2) | protein interactions | 27429 | 71 | 22 | 17029 | 2761 |
RMND5A,USP7,PDCD6IP,MKLN1,BIRC3,HPDL,WDYHV1,XIAP,TIA1,NADK2,ARMC8,MAPK14,PDXDC1,TRIM28,APP,BIRC2,MAPK3,CDK5,NDUFV1,KHSRP,TUBB,HTRA2 |
| 1.437e-03 | -6.55 | FPR2 (formyl peptide receptor 2) | protein interactions | 2358 | 71 | 22 | 17029 | 2761 |
PIGN,TMEM184B,GPR89A,HSDL1,RRAGC,NIPA2,PXMP2,SLC29A1,SLC35B2,ATP5F1B,REEP5,PDXDC1,TMEM161B,TRIM4,CERS6,ARL6IP1,ARAP1,LMBR1,NCLN,REEP4,CHPT1,MZT2B |
| 1.446e-03 | -6.54 | human chr1q42.13 | chromosome location | human chr1q42.13 | 43 | 12 | 26185 | 2809 |
JMJD4,GALNT2,GUK1,MRPL55,COQ8A,TRIM11,URB2,RAB4A,C1orf35,ABCB10,TAF5L,ARF1 |
| 1.447e-03 | -6.54 | Znf_RanBP2 | interpro domains | IPR001876 | 24 | 10 | 18492 | 2768 |
MDM2,EWSR1,TAB2,NEIL3,NUP153,ZRANB2,FUS,ZRANB1,NPLOC4,RYBP |
| 1.450e-03 | -6.54 | tRNA processing | biological process | GO:0008033 | 124 | 32 | 17256 | 2622 |
SEPHS2,CTU2,RPP25,METTL1,KARS,TP53RK,TRMT6,TYW1,NSUN2,METTL2A,LAGE3,ELP4,C2orf49,GTPBP3,DUS3L,DUS4L,ELP5,THADA,LSM6,GRSF1,TRMU,WDR4,TYW5,POP7,RTCB,FTSJ1,DUS2,TRMT10B,OSGEPL1,CPSF4,TSEN15,TYW1B |
| 1.450e-03 | -6.54 | error-prone translesion synthesis | biological process | GO:0042276 | 20 | 9 | 17256 | 2622 |
RPA2,RFC3,PCNA,POLK,RPS27A,RFC2,MAD2L2,NEXMIF,RPA1 |
| 1.454e-03 | -6.53 | Signaling by Rho GTPases | REACTOME pathways | R-HSA-194315 | 427 | 94 | 10287 | 1696 |
WASF2,RHOG,H2AFZ,TRIP10,ACTR3,RAC1,MYH9,NUF2,KIF2C,KTN1,MIS12,CALM2,VAV1,AHCTF1,CDC42,KIF14,PIK3R2,NUP107,CDKN1B,ABI1,DVL2,SEH1L,PLK1,ARHGAP17,NCK1,GOPC,ARHGAP45,TAOK1,WIPF1,ARHGDIB,AURKB,H2AFV,CENPU,KIF2A,PPP2CA,WAS,PPP2R5A,DSN1,LIMK1,ITGB1,H2AFX,ACTB,ROCK1,DVL1,H3F3A,MAPK1,MYL12B,MAPRE1,PPP1R12A,RHOC,TRIO,CENPF,VAV2,CDCA8,KLC1,RACGAP1,MYO9B,NCKAP1,PMF1,SPDL1,RTKN,KIF5B,ARPC5,ARHGEF1,PRC1,ARHGEF2,KNTC1,CENPM,NUP85,NCOA2,NUDC,PDPK1,CYFIP1,RHOA,NET1,ARHGEF12,RANGAP1,CYFIP2,RHOT1,MEN1,ARPC1A,RHOT2,RHOB,ARHGAP15,MAPK3,KIF18A,BIRC5,ARAP1,YWHAZ,CENPT,NDE1,MYO9A,YWHAH,ARHGAP23 |
| 1.456e-03 | -6.53 | GSE37533_UNTREATED_VS_PIOGLIZATONE_TREATED_CD4_TCELL_PPARG2_AND_FOXP3_TRASDUCED_DN | MSigDB lists | GSE37533_UNTREATED_VS_PIOGLIZATONE_TREATED_CD4_TCELL_PPARG2_AND_FOXP3_TRASDUCED_DN | 145 | 36 | 17377 | 2626 |
RMND5A,ASH1L,GPR132,PDCD6IP,GPBP1L1,WDYHV1,MRI1,LETMD1,GLUD1,ABCB10,UBE4A,LANCL1,FAM8A1,TUBGCP2,CYHR1,NDUFV1,RAB4A,FNIP2,MAVS,CYB5R1,MRPL40,TMEM8A,CFL1,JMJD4,ZDHHC18,CLCN3,ELOVL5,MLEC,PRKDC,ZMYND11,CUL3,RBM38,MYO18A,WIPI2,PPP6R2,CAPN1 |
| 1.456e-03 | -6.53 | LIN_NPAS4_TARGETS_UP | MSigDB lists | LIN_NPAS4_TARGETS_UP | 145 | 36 | 17377 | 2626 |
SEPHS2,KIF3B,MTX3,GMCL1,CDC42SE2,NANS,FAM8A1,RBM4,BZW2,RRN3,USF1,RBM34,AP2B1,SLC27A4,CDKN1B,LRSAM1,SLC35A1,ATP2C1,CAMSAP1,HSDL1,NUP155,CHMP2B,AP4E1,ABCF1,RAB2B,BSDC1,MAGED2,SEC61A1,NIP7,CAPN7,VCPIP1,PPP1R11,ZDHHC7,CHMP4B,B4GALT3,CHMP7 |
| 1.462e-03 | -6.53 | single-stranded DNA-dependent ATPase activity | molecular function | GO:0043142 | 13 | 7 | 17224 | 2647 |
RFC3,RAD18,RFC2,HELB,CHTF18,DHX9,POLQ |
| 1.465e-03 | -6.53 | ATAGGAA,MIR-202 | MSigDB lists | ATAGGAA,MIR-202 | 95 | 26 | 17377 | 2626 |
TCF12,LUZP1,GPBP1L1,ACSL3,MED13L,ATXN1,KRAS,BICD2,RAB22A,RNF121,DNAJC10,TTC13,PTEN,MAPK6,TYW5,EI24,BCL2,TARDBP,ANP32E,CNOT6,FAM76B,NR2F2,PPP5C,LDLRAD3,STAT3,SENP1 |
| 1.465e-03 | -6.53 | AKT1 (AKT serine/threonine kinase 1) | protein interactions | 207 | 343 | 77 | 17029 | 2761 |
CYLD,TSC2,RAF1,RAC1,XIAP,CSNK2A1,NSD3,IRF3,BCL2L1,PLXNA1,MAPK14,APP,MXD1,FANCI,TERF2IP,PDK2,APLP2,PA2G4,MDM2,CDKN1B,TTC3,CTDSP2,DNMT1,CDC37,SRPK2,DCTN1,METTL1,VHL,AKT2,ATXN1,BRCA1,CCNF,PPP2CA,ATP1A1,AHNAK,SMAD2,HSPA4,STAT1,FKBP5,ACTB,ARRB2,SMAD4,TUBB,RHEBL1,NCOR2,PHB2,ACAP1,ARFIP2,AKT1S1,DNAJB1,FOXO3,PTEN,AHSA1,ATP6V0A2,YBX1,CREB1,PDPK1,PPP3CA,PRKDC,LDHA,PDE3B,MARK2,APPL1,CNOT9,TSC1,NSF,CSK,ZHX1,PIAS2,MDH1,DDX5,YWHAZ,TCOF1,NR2F2,MAP3K5,CD81,EGLN1 |
| 1.470e-03 | -6.52 | GSE17721_POLYIC_VS_CPG_0.5H_BMDC_DN | MSigDB lists | GSE17721_POLYIC_VS_CPG_0.5H_BMDC_DN | 192 | 45 | 17377 | 2626 |
TM9SF4,HLA-E,MRPS26,RAB23,SMC6,ASAH1,NIT2,FAM8A1,PNO1,GTPBP3,NFATC3,AHCTF1,NDUFB4,CYB5R1,SLC35C2,SLC35A1,DRAM2,EBAG9,RPAP3,MOB4,LAP3,FOPNL,LYRM1,CUL3,ZNF574,MTMR6,NUSAP1,BICD2,MCFD2,RAB1A,ANKRD46,RDH11,BRMS1,ALDH3B1,OSBPL11,CDC16,KIF18A,VPS26B,DCK,PGRMC1,ACAT1,ANP32E,ATP6V1C1,PGAM1,AP2S1 |
| 1.470e-03 | -6.52 | GSE15735_2H_VS_12H_HDAC_INHIBITOR_TREATED_CD4_TCELL_DN | MSigDB lists | GSE15735_2H_VS_12H_HDAC_INHIBITOR_TREATED_CD4_TCELL_DN | 192 | 45 | 17377 | 2626 |
GOLIM4,ABCA3,HJURP,AGRN,HNRNPUL2,TKT,TATDN3,SUMF1,B4GALT4,SLC12A9,SPAG5,STARD9,RALB,RINL,DPYSL2,IL6ST,MEGF8,FAM89B,ARHGEF2,KIFAP3,MAP3K14,SLC35C2,TFG,ARID4A,PREB,ZNF524,TK1,TRAFD1,ERLIN1,MYBL2,CKAP2L,BRCA1,SMC2,CCNF,CBFB,POLE,SURF4,RBL1,DCK,CORO1C,ZNF367,SMAD1,NGLY1,GEN1,LRP8 |
| 1.470e-03 | -6.52 | NMT1 (N-myristoyltransferase 1) | protein interactions | 4836 | 89 | 26 | 17029 | 2761 |
TGFB1,RPL38,DHX9,CDCA3,CSNK2A1,MCM2,PRKACA,LYN,EDRF1,ABCF1,FKBP3,RPL23A,CAPN2,PA2G4,PDCD6,IARS,QARS,RTCB,YBX1,RPL19,RP2,ARL5A,CAPN1,HNRNPM,DYNC1LI2,DCTN1 |
| 1.471e-03 | -6.52 | Pyruvate metabolism and Citric Acid (TCA) cycle | REACTOME pathways | R-HSA-71406 | 49 | 17 | 10287 | 1696 |
SUCLG1,MDH2,IDH3A,LDHA,GLO1,OGDH,HAGH,SDHA,PDHX,MPC1,SDHB,PDK2,CS,SUCLG2,SLC16A1,IDH3B,LDHB |
| 1.474e-03 | -6.52 | DDX39A (DExD-box helicase 39A) | protein interactions | 10212 | 80 | 24 | 17029 | 2761 |
MOB4,SARNP,CELSR2,THOC1,BABAM1,EXOSC9,PAWR,BRCA1,DDX39A,API5,PABPC4,TERF2IP,C12orf10,RPN1,DDOST,HIPK2,AHSA1,UBA5,NIPSNAP2,TERF1,PABPC1,TERF2,SRPK2,CDC5L |
| 1.476e-03 | -6.52 | GSE17974_1.5H_VS_72H_IL4_AND_ANTI_IL12_ACT_CD4_TCELL_UP | MSigDB lists | GSE17974_1.5H_VS_72H_IL4_AND_ANTI_IL12_ACT_CD4_TCELL_UP | 171 | 41 | 17377 | 2626 |
ATXN3,NOP2,RRP15,URB2,SRSF6,TRMT6,CERK,MED13L,RAPGEF6,RNF103,JMY,WDR48,CREM,ZNF335,ZNF200,MAML1,CDK12,CSNK1G3,FYTTD1,SAMD4B,PLK3,NAGPA,EXOSC6,TNFAIP3,PBXIP1,ELL2,RB1CC1,COQ10B,BTG2,RABIF,MTMR6,GOSR1,SCARB2,PON2,FBXO28,SPATA2,RNF38,CHMP7,CHPF2,CSNK1D,ATMIN |
| 1.476e-03 | -6.52 | GSE7348_LPS_VS_TOLERIZED_AND_LPS_STIM_MACROPHAGE_UP | MSigDB lists | GSE7348_LPS_VS_TOLERIZED_AND_LPS_STIM_MACROPHAGE_UP | 171 | 41 | 17377 | 2626 |
TBC1D12,NCOR2,ATXN3,REPS2,NOP2,MUM1,ADO,CERK,NUP54,MEF2A,EIF2AK4,EIF1B,SLC20A1,ARID1B,GIT2,ARL6IP6,INPP5A,ADCY9,ATP13A3,DAPK1,SLC27A4,FOXN2,PCYT2,RNF19A,FTSJ3,RLIM,SNX8,TXNL1,SNX25,GTPBP4,PDE3B,EIF3A,DDX23,CAND1,SYNCRIP,BRWD1,PKD2,RRS1,WDR91,USP53,FUBP1 |
| 1.478e-03 | -6.52 | primary miRNA processing | biological process | GO:0031053 | 10 | 6 | 17256 | 2622 |
HNRNPA2B1,SMAD2,SMAD1,DGCR8,METTL3,SRRT |
| 1.478e-03 | -6.52 | TP63 (tumor protein p63) | protein interactions | 8626 | 131 | 35 | 17029 | 2761 |
CCNC,HNRNPAB,CDT1,AGO2,DHX9,UBE2I,PSMD2,MDM2,SEC24C,UPF2,N4BP2,CARM1,FOXK1,ASPM,BRCA1,UBE4B,CCT8,SNRPA,RPSA,DDX23,FAS,GOLGA4,SYNCRIP,PPP2R5A,HNRNPR,SAFB,HIPK2,RNF38,PML,STK11,ATP5F1A,CHEK2,FUS,COPS6,CDKN2A |
| 1.479e-03 | -6.52 | GENTILE_RESPONSE_CLUSTER_D3 | MSigDB lists | GENTILE_RESPONSE_CLUSTER_D3 | 62 | 19 | 17377 | 2626 |
GINS1,TLK1,AMD1,SLBP,KIF23,CDC6,MCL1,SLC25A44,ZFAND5,RHOB,CRKL,SERTAD2,TNFAIP8,MBD2,SIAH2,ACADM,ZMIZ1,TIPARP,COIL |
| 1.479e-03 | -6.52 | KEGG_COLORECTAL_CANCER | MSigDB lists | KEGG_COLORECTAL_CANCER | 62 | 19 | 17377 | 2626 |
TGFB1,RHOA,AKT2,RAF1,RAC1,KRAS,CYCS,APPL1,MAPK3,SMAD2,BIRC5,AXIN1,PIK3R2,MSH2,AXIN2,BCL2,MAPK1,SMAD4,MSH6 |
| 1.482e-03 | -6.51 | JIANG_AGING_CEREBRAL_CORTEX_DN | MSigDB lists | JIANG_AGING_CEREBRAL_CORTEX_DN | 53 | 17 | 17377 | 2626 |
CSDE1,PPP2CA,RAB14,PLD3,ATP1A1,ATP2A2,NSF,DAD1,ACTR3,OAZ2,CS,TIA1,GORASP2,SRSF5,SEPT7,CSNK1A1,DCTN1 |
| 1.482e-03 | -6.51 | GO_RIBOSOMAL_SMALL_SUBUNIT_BIOGENESIS | MSigDB lists | GO_RIBOSOMAL_SMALL_SUBUNIT_BIOGENESIS | 53 | 17 | 17377 | 2626 |
RPS15,RPS10,RPL38,RPS24,UTP3,TSR2,RPSA,RRP36,KRR1,UTP20,NOL11,LSM6,UTP18,RPS14,TBL3,RRS1,BYSL |
| 1.482e-03 | -6.51 | REACTOME_SCFSKP2_MEDIATED_DEGRADATION_OF_P27_P21 | MSigDB lists | REACTOME_SCFSKP2_MEDIATED_DEGRADATION_OF_P27_P21 | 53 | 17 | 17377 | 2626 |
PSMB7,PSMA1,CUL1,PSMB9,PSMD9,PSMB3,PSMC4,PSMD2,PSMA6,CCNA2,PSMD1,RPS27A,PSMD3,PSMD8,CDKN1B,CDK2,PSMC1 |
| 1.488e-03 | -6.51 | CA2 (carbonic anhydrase 2) | protein interactions | 760 | 19 | 9 | 17029 | 2761 |
ANKZF1,PCNA,EWSR1,HUWE1,DYNLL1,USP42,CUL1,SLC4A2,FUS |
| 1.488e-03 | -6.51 | Bcl7b (B cell CLL/lymphoma 7B) | protein interactions | 12054 | 19 | 9 | 17029 | 2761 |
PHF10,ARID2,SMARCA4,BRD7,PBRM1,ARID1A,SMARCE1,ARID1B,SMARCD1 |
| 1.490e-03 | -6.51 | REACTOME_PYRUVATE_METABOLISM_AND_CITRIC_ACID_TCA_CYCLE | MSigDB lists | REACTOME_PYRUVATE_METABOLISM_AND_CITRIC_ACID_TCA_CYCLE | 40 | 14 | 17377 | 2626 |
SDHB,PDK2,SUCLG1,MDH2,IDH3A,CS,LDHA,SUCLG2,SLC16A1,OGDH,IDH3B,SDHA,PDHX,LDHB |
| 1.490e-03 | -6.51 | chr2p11 | MSigDB lists | chr2p11 | 40 | 14 | 17377 | 2626 |
RMND5A,IMMT,SNRNP200,SUCLG1,ARID5A,STARD7,USP39,TGOLN2,KDM3A,KCMF1,MRPL19,MAT2A,RNF103,C2orf68 |
| 1.490e-03 | -6.51 | PID_FOXM1_PATHWAY | MSigDB lists | PID_FOXM1_PATHWAY | 40 | 14 | 17377 | 2626 |
PLK1,RB1,NFATC3,CCNA2,BIRC5,FOXM1,CENPF,AURKB,CDC25B,CHEK2,CCNB1,CDK2,CCNB2,CDKN2A |
| 1.513e-03 | -6.49 | APOBEC3D (apolipoprotein B mRNA editing enzyme catalytic subunit 3D) | protein interactions | 140564 | 54 | 18 | 17029 | 2761 |
YTHDC1,JMJD4,HNRNPUL2,KIF23,THRAP3,SAFB2,SLTM,PABPC4,ZFR,UPF1,STRBP,SYNCRIP,HNRNPR,SAFB,ZNF326,DUSP11,ZC3H3,SRSF10 |
| 1.513e-03 | -6.49 | L3MBTL2 (L3MBTL2, polycomb repressive complex 1 subunit) | protein interactions | 83746 | 54 | 18 | 17029 | 2761 |
ZNF296,PHF10,MAX,MTA2,PCGF6,MIER2,WDR5,MBD3,MEAF6,CBX3,RB1,MTA1,TFDP1,KBTBD7,TFDP2,ASB6,HDAC2,RYBP |
| 1.513e-03 | -6.49 | CTCF (CCCTC-binding factor) | protein interactions | 10664 | 54 | 18 | 17029 | 2761 |
H2AFZ,SUZ12,TOP2B,LMNA,POLR2A,CAND1,TFAP4,SMC3,KPNA4,DGCR8,H2AFX,YBX1,CHMP4B,KPNA2,YY1,FBL,SMAD4,IFI16 |
| 1.513e-03 | -6.49 | TRMT1 (tRNA methyltransferase 1) | protein interactions | 55621 | 54 | 18 | 17029 | 2761 |
KARS,LARS,HEMK1,WDYHV1,AGO2,CHCHD2,ATP6V1B2,RSAD1,XRCC5,CSDE1,EPRS,IARS,QARS,CTPS1,SENP1,TERF1,ZNF598,NUDC |
| 1.513e-03 | -6.49 | SGO1 (shugoshin 1) | protein interactions | 151648 | 54 | 18 | 17029 | 2761 |
PLK1,HNRNPAB,RB1CC1,ZNF768,UBR2,PRKDC,CHD1L,CDCA8,KIF2C,AURKB,CHMP2B,ECH1,XRCC5,PPP2CA,PPP2R5A,HPS5,RPLP1,LRRC59 |
| 1.513e-03 | -6.49 | Sgo2a (shugoshin 2A) | protein interactions | 68549 | 54 | 18 | 17029 | 2761 |
CLPTM1,TCF12,ADAM17,GOLIM4,EWSR1,NOP2,EIF3D,MIER1,CENPF,CDCA3,COG1,PPP2CA,CEP104,PPP2R5A,JAK1,LTN1,IGBP1,CCAR1 |
| 1.513e-03 | -6.49 | UBE2V2 (ubiquitin conjugating enzyme E2 V2) | protein interactions | 7336 | 54 | 18 | 17029 | 2761 |
MOB4,RHOA,SUV39H2,SIAH1,POLK,SHPRH,UBXN1,TTC9C,RAD23B,XIAP,UBE2V1,ZRANB2,TRIM32,ATP6V1B2,TTLL12,UBE2M,SSSCA1,USP34 |
| 1.513e-03 | -6.49 | FMR1 (fragile X mental retardation 1) | protein interactions | 2332 | 54 | 18 | 17029 | 2761 |
CYFIP1,STAU1,MZT1,CYLD,THOC1,NCK1,SUZ12,PRKAA1,GBA,BCLAF1,FXR1,UBE2I,CYFIP2,SPAG5,WWP2,EIF4A3,YBX1,IFI16 |
| 1.515e-03 | -6.49 | GSE25088_CTRL_VS_IL4_AND_ROSIGLITAZONE_STIM_STAT6_KO_MACROPHAGE_DN | MSigDB lists | GSE25088_CTRL_VS_IL4_AND_ROSIGLITAZONE_STIM_STAT6_KO_MACROPHAGE_DN | 166 | 40 | 17377 | 2626 |
PARP12,AGRN,DCAF15,HLA-E,ABCC10,CDT1,UBE2Z,ZNF267,PDCD7,PCBP1,STAM,FBXO22,FAM192A,FANCL,RAB8A,KDM2A,MTMR4,EFTUD2,XRCC2,ORC3,EIF5,ATP6V1G1,VOPP1,ELL2,GOPC,HNRNPF,MAP7D1,TSR2,LSG1,TMEM41A,TBPL1,FAM122A,KPNA2,CDK2,PARP10,CCDC59,SSSCA1,RNF114,ADNP2,CCDC137 |
| 1.515e-03 | -6.49 | GSE10856_CTRL_VS_TNFRSF6B_IN_MACROPHAGE_DN | MSigDB lists | GSE10856_CTRL_VS_TNFRSF6B_IN_MACROPHAGE_DN | 166 | 40 | 17377 | 2626 |
BCCIP,CMAS,UNK,NDUFA5,GNPNAT1,FAM207A,MRPL39,FAM129A,MRPS26,CIB1,RAB23,DNAJC24,JMJD6,EBNA1BP2,MCTS1,TMEM69,NUS1,UCHL5,IMPAD1,ATIC,SSBP3,TAP2,LONRF3,DHX29,PIP4K2C,SYVN1,DCUN1D5,METTL22,SLC50A1,ECH1,ALKBH6,PRIM1,DERL1,CDC27,NIP7,MAPK6,C1orf109,ITGB1,ACADM,RRS1 |
| 1.518e-03 | -6.49 | GSE42088_UNINF_VS_LEISHMANIA_INF_DC_2H_DN | MSigDB lists | GSE42088_UNINF_VS_LEISHMANIA_INF_DC_2H_DN | 187 | 44 | 17377 | 2626 |
RPS15,IER2,TSC22D3,SRSF6,NACA,TKT,CHD1,RPL11,RPL23A,PRNP,APLP2,ADD3,RPL17,PPCDC,RPL19,TAGLN2,FBL,CNPY3,RBM15B,EIF3L,RPL29,MAPRE2,RPL35,RPL8,RPL38,RPL6,RPS10,RPS24,ICAM2,RPL27A,RPS9,EIF3H,RPL36,NSA2,RPL37,PFDN5,NEK1,RPL32,FTSJ1,HMGB2,SRSF3,BTF3,FAU,LTA4H |
| 1.518e-03 | -6.49 | GSE27670_BLIMP1_VS_LMP1_TRANSDUCED_GC_BCELL_DN | MSigDB lists | GSE27670_BLIMP1_VS_LMP1_TRANSDUCED_GC_BCELL_DN | 187 | 44 | 17377 | 2626 |
CCDC93,PKP4,NSMCE4A,PTP4A3,AP1B1,FOXO3,XPR1,FERMT3,SLC25A36,KRR1,PHC2,CRKL,CAPN2,ERH,SUB1,SMC3,INPP5A,HDAC7,RAB4A,CAPZA1,CNN2,CLTB,ABI1,CCT2,FAM49B,GABPA,SNX2,WDHD1,WDR82,CDC6,WDR81,MEF2D,TOLLIP,NDRG3,ZNF282,PSMD3,DCK,BCL7C,LY75,GALNT10,CCNB2,MAPK1,VPS29,SMARCD1 |
| 1.518e-03 | -6.49 | GSE15930_STIM_VS_STIM_AND_TRICHOSTATINA_24H_CD8_T_CELL_DN | MSigDB lists | GSE15930_STIM_VS_STIM_AND_TRICHOSTATINA_24H_CD8_T_CELL_DN | 187 | 44 | 17377 | 2626 |
SEPHS2,KIF3B,SMAP1,NQO1,DNAJB2,SLC20A1,SYNRG,KTN1,FZD6,MBD4,FKBP1A,SEC11A,VMP1,TANK,PDCD2,TCEA1,NFU1,NCOA2,DVL2,SP3,PTPN18,SNX2,PPIE,PIP4K2C,WDHD1,NUSAP1,GALK2,MEF2D,DCUN1D5,SEPT7,MRPS14,SMAD2,POLR2J,CCDC6,LUC7L3,LRPPRC,OGT,LY75,RBBP4,CHPT1,PGAM1,PSMC1,TSPAN5,S100PBP |
| 1.518e-03 | -6.49 | GSE3920_UNTREATED_VS_IFNB_TREATED_ENDOTHELIAL_CELL_UP | MSigDB lists | GSE3920_UNTREATED_VS_IFNB_TREATED_ENDOTHELIAL_CELL_UP | 187 | 44 | 17377 | 2626 |
SKA3,GXYLT1,CDT1,PTTG1,KLF13,CHKB,KIF2C,CNTROB,RGS2,STMN1,ETS1,FZD6,FBXO22,FBXO3,ZCCHC2,AP1M1,PDS5B,CYB5R1,CABLES2,AQR,MCMBP,N4BP2,NIPAL3,ORAI2,TACC1,GABPA,PBXIP1,PPP1R21,MAP4K4,KCTD20,EZR,WDR82,MTMR12,ARID1A,KLF6,MARK2,VEZF1,PDCD6,UAP1,DCK,LIMK1,KBTBD7,VPS4A,SMAD4 |
| 1.518e-03 | -6.49 | GSE17721_0.5H_VS_24H_PAM3CSK4_BMDC_DN | MSigDB lists | GSE17721_0.5H_VS_24H_PAM3CSK4_BMDC_DN | 187 | 44 | 17377 | 2626 |
POLA2,HSPH1,GORASP1,DHPS,RAF1,WDR13,MAGED1,C16orf87,CIB1,CHIC2,CHAC2,LACTB2,MAP1LC3B,CPNE3,C18orf32,MDM2,ATP2A2,SNX18,AHSA1,CAPZA1,DAPK1,TNPO2,SLC27A4,CABLES2,UBE2M,PTPRK,ACSL5,TK1,NET1,LRBA,WBP2,RHOT1,NEU1,TMEM184C,CDKN2AIPNL,JAK1,CDC27,SERF2,RAB24,LUC7L3,DBI,PPP1R11,AKNA,HDAC2 |
| 1.518e-03 | -6.49 | GSE3982_EOSINOPHIL_VS_CENT_MEMORY_CD4_TCELL_UP | MSigDB lists | GSE3982_EOSINOPHIL_VS_CENT_MEMORY_CD4_TCELL_UP | 187 | 44 | 17377 | 2626 |
PLXNC1,EYA1,TKT,ASAH1,NOTCH2,SLC25A44,SNN,ATP6V1B2,PSEN1,RUFY1,CMTM6,COPB2,MAN1A1,EBP,APLP2,PTEN,RALB,MCMBP,ATP6V0D1,MYO5A,ORAI2,MAPKAPK3,TACC1,CREG1,RB1CC1,ERLIN1,SELPLG,PGS1,CRNKL1,FRAT2,RABIF,RTF1,USP22,STYXL1,TFEB,DERL1,MTHFD2,ZDHHC7,MEGF9,MRFAP1L1,ZNF268,USP11,ZMIZ1,PDCD4 |
| 1.518e-03 | -6.49 | GSE5542_IFNG_VS_IFNA_AND_IFNG_TREATED_EPITHELIAL_CELLS_6H_DN | MSigDB lists | GSE5542_IFNG_VS_IFNA_AND_IFNG_TREATED_EPITHELIAL_CELLS_6H_DN | 187 | 44 | 17377 | 2626 |
MIF,PTMS,MUT,MAGED1,ARGLU1,PRPF39,PITHD1,FOXO3,LMNA,CAPN2,SAR1A,HUWE1,MECR,HADHB,AHDC1,SS18L1,C8orf59,HTRA2,TCTEX1D2,IDH3A,PRKAR1B,RPL38,SEPT8,MRPS10,TOR1AIP2,MAP7D1,ABHD11,MEF2D,AZI2,ICAM2,MTR,RPS9,SOCS7,EIF3K,UTP20,DNAJC10,KEAP1,ORMDL2,CERS6,CORO1C,STAT1,ACAT1,NCOA1,NIPA1 |
| 1.518e-03 | -6.49 | multi-organism transport | biological process | GO:0044766 | 71 | 21 | 17256 | 2622 |
NDC1,NUP188,THOC1,RAB7A,RAE1,NUP54,NUP155,NMT2,NUP205,NUP210,KPNA1,KPNA4,RPS27A,NUP107,NUP62,KPNA2,NUP153,NUP58,NUP85,AAAS,SEH1L |
| 1.518e-03 | -6.49 | vesicle-mediated transport to the plasma membrane | biological process | GO:0098876 | 71 | 21 | 17256 | 2622 |
CCDC93,SNX27,ANKRD27,GCC2,GOLPH3L,SYS1,RAB11B,GOPC,ANK3,CHIC2,MACF1,RAB11A,OPTN,RAB8A,GOLGA4,GOLGA7,GRIPAP1,NSF,DNM2,EXOC4,VPS29 |
| 1.518e-03 | -6.49 | multi-organism localization | biological process | GO:1902579 | 71 | 21 | 17256 | 2622 |
NDC1,NUP188,THOC1,RAB7A,RAE1,NUP54,NUP155,NMT2,NUP205,NUP210,KPNA1,KPNA4,RPS27A,NUP107,NUP62,KPNA2,NUP153,NUP58,NUP85,AAAS,SEH1L |
| 1.529e-03 | -6.48 | exocytosis | biological process | GO:0006887 | 787 | 150 | 17256 | 2622 |
ADA2,RAB14,ADAM10,HEXB,NHLRC3,GYG1,MAPK14,CMTM6,KCMF1,PCYOX1L,CDK5,PA2G4,RAB8A,PSMD1,RAP1A,AP1M1,TXLNA,KCNAB2,NRAS,ARHGAP45,CYSTM1,RAB5B,AGPAT2,TMED10,CAB39,ATP6V0C,CLU,ROCK1,CAPN1,SVIP,DNAJC5,GMFG,NKD2,LAMTOR3,ASAH1,B4GALT1,CDK13,MAN2B1,RAB6A,PPP3CB,PSEN1,TMEM179B,CD59,GNS,ARPC5,VMP1,RIMS3,OSTF1,MVP,LPCAT1,SYTL3,CYFIP1,FTL,CREG1,WDR1,C1orf35,PKM,ARMC8,CCT8,XRCC5,CAND1,PI4K2A,MAGED2,CAT,NSF,SNAP23,ACLY,EXOC4,CTSA,GPI,UNC13C,RHOG,EXOC3,RAB11B,DYNLL1,RAC1,OLA1,NIT2,LYN,APP,CPNE3,APLP2,BRPF3,BRI3,CYB5R1,CORO1A,APOOL,TMBIM1,GM2A,CHP1,CPNE1,ENPP4,ARHGAP17,CCT2,TIMP2,RAB7A,PPIE,PSMB7,ATP6V0A1,TOLLIP,ALDH3B1,DSN1,DDOST,SURF4,RAB24,PSMD3,CANT1,PDXK,MAPK1,LTA4H,CHID1,TUBB,MIF,MANBA,PDAP1,HABP4,SRGN,VPS45,TMX3,RAB11A,PIP5K1C,FERMT3,PSMD2,CTSS,HUWE1,ANXA5,CNN2,TAGLN2,MYO5A,MICAL3,SPTAN1,TGFB1,MLEC,RHOA,FAM49B,SCFD2,HEBP2,NEU1,HSPA1B,RAB18,ATP6V1D,MAGT1,GOLGA7,SNAP29,FAM3C,PGRMC1,IMPDH1,PSAP,PGAM1,SNAPIN |
| 1.532e-03 | -6.48 | CHIARADONNA_NEOPLASTIC_TRANSFORMATION_KRAS_UP | MSigDB lists | CHIARADONNA_NEOPLASTIC_TRANSFORMATION_KRAS_UP | 120 | 31 | 17377 | 2626 |
SEPHS2,TGFB1,TCF12,CYTIP,IVNS1ABP,ANKH,DHX9,RRM1,RRM2,SLBP,RANGAP1,SMC2,MYEF2,BZW2,NAP1L1,PCNA,MED10,RBL1,ERGIC3,FUT8,FAM3C,MAPK6,H2AFX,ANP32E,AHCY,RBM3,SPTSSA,SLC12A2,TIPARP,DNMT1,SSRP1 |
| 1.533e-03 | -6.48 | GO_CELLULAR_RESPONSE_TO_TOPOLOGICALLY_INCORRECT_PROTEIN | MSigDB lists | GO_CELLULAR_RESPONSE_TO_TOPOLOGICALLY_INCORRECT_PROTEIN | 115 | 30 | 17377 | 2626 |
BAK1,SEC61B,ATXN3,ADD1,SEC61G,CXXC1,SDF2L1,SYVN1,EDEM2,SERP1,RHBDD1,LMNA,DNAJB9,SSR1,YIF1A,ANKZF1,DERL1,SEC31A,RNF121,SHC1,SEC61A1,TATDN2,ATF6,ASNA1,PDIA6,ATP6V0D1,CTDSP2,RNF5,PREB,DCTN1 |
| 1.542e-03 | -6.47 | recombinational repair | biological process | GO:0000725 | 90 | 25 | 17256 | 2622 |
RECQL,RAD51AP1,SMC6,BRCA1,BLM,WDR48,GINS4,RAD54B,RPA1,RPA2,RFWD3,RAD51C,PALB2,TONSL,NSMCE2,XRCC2,NABP2,NABP1,H2AFX,XRCC3,YY1,GEN1,SPIDR,RAD51D,POLQ |
| 1.543e-03 | -6.47 | GO_REGULATION_OF_SEQUENCE_SPECIFIC_DNA_BINDING_TRANSCRIPTION_FACTOR_ACTIVITY | MSigDB lists | GO_REGULATION_OF_SEQUENCE_SPECIFIC_DNA_BINDING_TRANSCRIPTION_FACTOR_ACTIVITY | 351 | 74 | 17377 | 2626 |
USP7,CYLD,SMARCA4,TAF6L,MAPK14,PARK7,PRNP,TERF2IP,PSMA6,SP100,GLIS2,SIVA1,MAVS,ATF2,MTPN,TRIM14,DVL2,RLIM,TRIM8,RNF25,LRP5,UBE2V1,ERC1,BRMS1,TAB2,RPS27A,HIPK2,TICAM1,TRIM32,CLU,TRIM52,TRAF5,ARRB2,MAPK1,LRP8,HDAC2,RHEBL1,DDX58,PHB2,DAP,TCF3,CIB1,EIF2AK4,FZD6,JMY,MAD2L2,WWP2,DDRGK1,CFLAR,RB1,PTEN,BUD31,ARHGEF2,TGFB1,PPP3CA,TRAPPC9,TNFAIP3,KRAS,MEN1,PRMT2,HSPA1B,MAPK3,CAT,TRIM26,KEAP1,PRDX3,CEBPG,PIAS2,NLRC5,TAF12,TAF6,PARP10,CDKN2A,EGLN1 |
| 1.553e-03 | -6.47 | GSE34156_NOD2_LIGAND_VS_TLR1_TLR2_LIGAND_24H_TREATED_MONOCYTE_DN | MSigDB lists | GSE34156_NOD2_LIGAND_VS_TLR1_TLR2_LIGAND_24H_TREATED_MONOCYTE_DN | 161 | 39 | 17377 | 2626 |
BCCIP,HSPH1,MAGEH1,CDS2,TOMM20,SARNP,RPLP2,SLC41A1,FAM136A,RPAIN,REPS1,WRNIP1,RPL11,KDM2A,ZNHIT6,RBM34,NOC2L,TTC3,ACAD8,FBL,FTSJ3,FGFR1OP2,SRSF10,TTPAL,YTHDC1,ZMYM5,RPL38,RPS10,JTB,PPWD1,RPSA,NSA2,CERS6,PDRG1,WDR59,CENPT,C11orf1,COIL,ANAPC4 |
| 1.553e-03 | -6.47 | GSE6259_DEC205_POS_DC_VS_BCELL_DN | MSigDB lists | GSE6259_DEC205_POS_DC_VS_BCELL_DN | 161 | 39 | 17377 | 2626 |
MIF,FGFR1OP,MRPL39,SNAPC4,GFM2,USP5,SF3B2,ZCCHC2,TPST1,ANAPC7,PPA1,USO1,RFC3,POLR2G,CSRP1,TMEM39A,RPL8,SLC25A22,DCLRE1C,AZI2,ASB13,STX16,PSMB9,RAB22A,ISG15,ARF4,TMEM184C,KEAP1,TXNDC16,GADD45B,BBX,PML,LY75,CHMP4B,NAA20,WDR91,LRP8,RNF114,DDX52 |
| 1.553e-03 | -6.47 | GTGCCAT,MIR-183 | MSigDB lists | GTGCCAT,MIR-183 | 161 | 39 | 17377 | 2626 |
TCF12,TMED7,PKP4,DAP,PLAGL2,MXD4,SLC44A1,FOXN2,ANKRD13C,FAM76B,SLC35A1,SCYL3,CSNK1G3,SRSF11,CLCN3,C16orf72,AMD1,POLR2D,EZR,MTMR6,VDAC1,SERP1,EML4,PHF6,PPP2CA,MAP3K4,PDCD6,L3MBTL3,OSBPL8,CSNK1G1,ITGB1,OGT,BAZ1B,SLAIN1,SLC22A23,PTDSS1,ABCA1,PDCD4,SSRP1 |
| 1.554e-03 | -6.47 | CCP110 (centriolar coiled-coil protein 110) | protein interactions | 9738 | 67 | 21 | 17029 | 2761 |
ACTR3,SMC2,CCNF,LYN,CAND1,CALM2,CEP104,PCM1,CDC16,CCDC14,CENPJ,SNAP23,ODF2,USP20,DVL1,GPI,COPS6,SASS6,CDK2,SSSCA1,DDB1 |
| 1.556e-03 | -6.47 | DOUGLAS_BMI1_TARGETS_DN | MSigDB lists | DOUGLAS_BMI1_TARGETS_DN | 301 | 65 | 17377 | 2626 |
COX15,PPCS,GNPDA1,KLHL18,RRAGC,CREBL2,TBC1D13,ELMOD2,MYEF2,BIRC2,SP100,NSRP1,RPRD1B,TMBIM1,CGGBP1,CLCN3,BIRC3,PBXIP1,DIDO1,AMDHD2,ARL5B,FOXRED1,PSMB9,OPTN,RBM47,STAT6,ARNTL,STAT1,MPV17,CLU,NGLY1,CSNK1D,MIF4GD,GOLPH3L,CCZ1,GADD45G,BTN3A1,AGPAT3,LANCL1,FZD6,TMEM179B,ARL6IP1,MVP,IFT46,ATP6V0D1,NIPAL3,PPP3CA,TNFAIP3,TACC1,HELB,TSPAN31,PIP4K2C,UBE4B,ICAM2,STYXL1,API5,ECH1,NEU1,TMEM127,DUSP3,CCZ1B,OSBPL8,MAPK6,ARAP1,S100PBP |
| 1.557e-03 | -6.47 | RAC1 (Rac family small GTPase 1) | protein interactions | 5879 | 220 | 53 | 17029 | 2761 |
POLA2,TRAF7,RHOC,VAV2,RAC1,TRIO,XIAP,MYH9,ARFIP2,CDC42SE2,NCKAP1,BIRC2,KTN1,PIP4K2A,MYL6B,VAV1,SH3BP1,ARHGEF2,UBE3B,TALDO1,STAT3,PHKG2,DVL2,CYFIP1,STAU1,ARHGAP17,NCK1,ARHGDIB,CDC23,PKM,ICMT,TOLLIP,RHOB,CLNS1A,ARHGAP15,RHEB,MAP3K4,PPP2CA,KPNA4,WAS,LTBP4,RBMX,CORO1C,STAT1,LRPPRC,ACTB,KPNA2,DVL1,CDK2,IGBP1,DEF6,ANXA11,PDF |
| 1.561e-03 | -6.46 | dephosphorylation | biological process | GO:0016311 | 283 | 62 | 17256 | 2622 |
CTDP1,PPP1R12A,EYA1,PPP1R15B,PTP4A3,CYCS,PPP3CB,EPHX2,DUSP22,PLPP5,UBLCP1,PTPN2,PPP1R3B,PDXP,TIGAR,PTEN,INPP5A,NT5DC1,MTMR4,IMPAD1,PPP4R1,LPIN2,PPP6C,PTPN11,BCL2,CDC25B,MINPP1,HDHD2,RPRD1B,ILKAP,CTDSP2,CAMK2G,IMPA2,TIMM50,PTPRK,NTPCR,PPP3CA,ACP2,PTPN18,RPRD1A,NCK1,PFKFB3,MTMR6,STYXL1,MTMR3,PPP2CA,PTPRF,ATP1A1,PPP2R5A,DUSP3,NT5C3B,PPM1G,PTPN7,PPA2,PPP3R1,DUSP11,PTPDC1,NANP,PPP5C,PLPP6,EYA2,PPP2R2D |
| 1.563e-03 | -6.46 | UCHL5 (ubiquitin C-terminal hydrolase L5) | protein interactions | 51377 | 215 | 52 | 17029 | 2761 |
TXN,NACA,INO80E,KCMF1,APP,LMNA,UBLCP1,SRXN1,RAD23A,PTPN2,PSMD2,PSMD1,PSMA6,HUWE1,UCHL5,RAD23B,CAPZA1,CFL1,KDELR1,FDFT1,PRPF19,CDC5L,TXNL1,FTL,RAB7A,PSMB7,E2F3,PSMA1,RFFL,ARMT1,BRCA1,PKM,COMMD4,PSMB9,PSMB3,CYB5A,PRDX1,PSMC4,IDE,SMAD2,PRDX3,PSMD8,PSMD3,E2F1,ANP32E,YWHAZ,ACTB,RUVBL2,YY1,E2F2,ECPAS,PSMC1 |
| 1.563e-03 | -6.46 | UBE2D3 (ubiquitin conjugating enzyme E2 D3) | protein interactions | 7323 | 215 | 52 | 17029 | 2761 |
DDX58,UBE2D3,USP7,TRIM11,XIAP,CSNK2A1,UBE4A,BIRC2,RNF103,WWP2,RFWD3,MDM2,PCNA,SIAH1,ZNRF2,HUWE1,FBXO7,UBE3C,RNF26,LRSAM1,RNF5,RLIM,PRPF19,STAU1,TRIM8,FOCAD,BIRC3,RBX1,RNF25,PCGF6,RFFL,TOPORS,UBE4B,BRCA1,SYVN1,MCM2,PCGF1,KDM1B,TRIM28,DAPK3,ISG15,TRIM26,RPLP1,SIAH2,UHRF2,PTAR1,RNF38,TRIM32,RNF14,UBE2C,SMURF1,RNF114 |
| 1.566e-03 | -6.46 | GSE14308_TH17_VS_NATURAL_TREG_UP | MSigDB lists | GSE14308_TH17_VS_NATURAL_TREG_UP | 182 | 43 | 17377 | 2626 |
MIF,CCNC,COMMD10,IMMT,UBE2E2,SKA3,PDCD6IP,AGTRAP,PRKCSH,HABP4,CUL1,CHCHD2,GYG1,BECN1,POLR3K,PRPF18,KIAA1147,RAB8A,PPIL2,POP7,SRI,RNF19A,MINPP1,IFT46,ATP6V1G1,SRSF10,FDFT1,CDC123,TSPYL4,RAD51AP1,MRS2,CCDC34,MTHFD2,TXNDC16,DBI,ARNTL,PRDX5,AEN,MEGF9,HMGB2,TMEM159,NDE1,AAAS |
| 1.566e-03 | -6.46 | PIGF_UP.V1_UP | MSigDB lists | PIGF_UP.V1_UP | 182 | 43 | 17377 | 2626 |
RECQL,UGP2,RGS2,DNAJB9,PAPOLA,KIF5B,RAP1A,PDCD10,SMC3,PPIG,IL6ST,TRMU,ATP13A3,UPF2,MAST2,CREB1,SMC4,SOCS5,SP3,MKLN1,KIAA0040,NEK7,DHX29,GMFB,SREK1,BCLAF1,NUP155,TOPORS,MARK2,TWISTNB,RDH11,NEK1,CDC27,OSBPL8,MAFK,MAPK6,LPCAT4,ADAM9,ZNF268,ACADM,RRS1,FAM208A,N4BP2L2 |
| 1.566e-03 | -6.46 | GSE17812_WT_VS_THPOK_KO_MEMORY_CD8_TCELL_UP | MSigDB lists | GSE17812_WT_VS_THPOK_KO_MEMORY_CD8_TCELL_UP | 182 | 43 | 17377 | 2626 |
MIF,HECA,RPS2,CCM2,ARID5A,ACAP1,RAB23,CDIPT,SLC20A1,RAPGEF6,ANKIB1,MAT2B,GOLM1,ADD3,RPL17,ZNF639,BDH1,RNF19A,METTL9,FRMD8,KCNAB2,CYTH1,NCK1,GALC,OXR1,LDB1,ACSL3,RABIF,RFFL,GALNT7,ICAM2,TANC1,PRMT2,NDRG3,EIF3H,GALNT2,FAM3C,WDR4,IMPDH1,LY75,SLC16A1,GALNT10,XRCC4 |
| 1.566e-03 | -6.46 | GSE21927_SPLEEN_C57BL6_VS_EL4_TUMOR_BALBC_MONOCYTES_UP | MSigDB lists | GSE21927_SPLEEN_C57BL6_VS_EL4_TUMOR_BALBC_MONOCYTES_UP | 182 | 43 | 17377 | 2626 |
GMFG,MPHOSPH8,TMBIM4,UBN1,TMEM41B,NACA,ASAH1,BTN3A1,ARGLU1,IP6K2,CCNL2,DAZAP2,MAPK14,ASXL2,FOXO3,GIT2,CCDC28A,RPL11,CAPN2,GSTK1,ADD3,MAML1,ABI1,ZNF189,ABCC5,USP34,ENPP4,GCC2,PBXIP1,RB1CC1,ZNF500,CIRBP,FBXO9,ADRB2,SRSF5,CYFIP2,CBFA2T2,MACF1,BSDC1,EIF3H,EPB41,OGT,TRIM52 |
| 1.566e-03 | -6.46 | STARK_PREFRONTAL_CORTEX_22Q11_DELETION_UP | MSigDB lists | STARK_PREFRONTAL_CORTEX_22Q11_DELETION_UP | 182 | 43 | 17377 | 2626 |
USP7,CDC40,ZNF445,PLXNC1,KIAA0100,UBR2,TRAK1,MYH9,CBLL1,ARGLU1,UBQLN2,CSNK1A1,SAFB2,CHKA,ZNF804A,SNX18,IMPAD1,LPIN2,FJX1,DNM2,TNPO2,H2AFY,TNRC18,PTPRK,SRSF11,SP3,SHOC2,TRIM8,MAPRE2,TIMP2,EID1,CYFIP2,NCDN,DOT1L,UBTF,FBXO41,RBM25,OGT,MEGF9,ROCK1,CPEB2,PFKP,EGLN1 |
| 1.566e-03 | -6.46 | GSE19941_UNSTIM_VS_LPS_STIM_IL10_KO_NFKBP50_KO_MACROPHAGE_UP | MSigDB lists | GSE19941_UNSTIM_VS_LPS_STIM_IL10_KO_NFKBP50_KO_MACROPHAGE_UP | 182 | 43 | 17377 | 2626 |
KRBA1,FOXM1,CENPF,RACGAP1,CDC42SE2,BLM,B4GALT4,ANKRD39,CDKN2C,RAP1A,DPYSL2,CENPJ,LPIN2,SLC35B4,PCYT2,CDC25B,CENPM,CYC1,PRADC1,CTDSP2,TERF2,ADCY7,GINS1,TDP1,DEAF1,ASPM,CKAP2L,HEBP2,ITM2A,CDCA2,RTF1,MTX1,PITPNB,KIF11,GINS4,NMT2,SUPT16H,FAM110A,PTER,PPA2,ANP32E,CCNB2,CSNK1D |
| 1.566e-03 | -6.46 | GSE13493_DP_VS_CD8POS_THYMOCYTE_UP | MSigDB lists | GSE13493_DP_VS_CD8POS_THYMOCYTE_UP | 182 | 43 | 17377 | 2626 |
WSB2,TCF12,PRPF38B,ZCCHC9,CASP6,AP3M2,CERK,CDC42SE2,SNN,HAUS2,TMCC3,WWP2,DBNDD1,RABGAP1L,KIF13B,PPIL2,TTC9C,RP2,TP53BP2,NAA35,ATP6V1G1,CLPTM1,FTL,TSPYL4,DENND4C,LDB1,MIER1,JTB,UBE4B,ARID1A,PRKRA,RAB22A,RDH11,CACNB1,FBXO41,ATP6V1D,PEX5,L3MBTL3,PKD2,CNOT6,DUSP11,RBPJ,CD81 |
| 1.571e-03 | -6.46 | Tat protein binding | molecular function | GO:0030957 | 10 | 6 | 17224 | 2647 |
SMARCA4,CTDP1,MDFIC,ACTB,TRIM32,DNAJA1 |
| 1.571e-03 | -6.46 | Apoptosis | KEGG pathways | hsa04210 | 138 | 36 | 7161 | 1149 |
CASP6,RAF1,GADD45G,XIAP,CYCS,BCL2L1,BIRC2,LMNA,CFLAR,CAPN2,CTSS,PIK3R2,BCL2,MAP3K14,HTRA2,SPTAN1,BAK1,PDPK1,NRAS,BIRC3,AKT2,PARP4,MCL1,KRAS,MAP2K2,FADD,FAS,MAPK3,CTSL,BIRC5,GADD45B,ACTB,MAP3K5,MAPK1,HRAS,CAPN1 |
| 1.571e-03 | -6.46 | Apoptosis | KEGG pathways | ko04210 | 138 | 36 | 7161 | 1149 |
CASP6,RAF1,GADD45G,XIAP,CYCS,BCL2L1,BIRC2,LMNA,CFLAR,CAPN2,CTSS,PIK3R2,BCL2,MAP3K14,HTRA2,SPTAN1,BAK1,PDPK1,NRAS,BIRC3,AKT2,PARP4,MCL1,KRAS,MAP2K2,FADD,FAS,MAPK3,CTSL,BIRC5,GADD45B,ACTB,MAP3K5,MAPK1,HRAS,CAPN1 |
| 1.573e-03 | -6.46 | GO_VESICLE_CYTOSKELETAL_TRAFFICKING | MSigDB lists | GO_VESICLE_CYTOSKELETAL_TRAFFICKING | 36 | 13 | 17377 | 2626 |
KIF5B,KIF3B,AP3S2,AP3M2,KIF23,KIFAP3,WDR81,CLN3,NDE1,RAB1A,AP3S1,MYO5A,SNAPIN |
| 1.573e-03 | -6.46 | KEGG_DNA_REPLICATION | MSigDB lists | KEGG_DNA_REPLICATION | 36 | 13 | 17377 | 2626 |
POLA2,RPA2,PCNA,RFC3,POLE,PRIM2,RNASEH2C,MCM5,RNASEH2A,MCM2,RFC2,RPA1,PRIM1 |
| 1.573e-03 | -6.46 | GO_DNA_DAMAGE_RESPONSE_DETECTION_OF_DNA_DAMAGE | MSigDB lists | GO_DNA_DAMAGE_RESPONSE_DETECTION_OF_DNA_DAMAGE | 36 | 13 | 17377 | 2626 |
DTL,RPA2,PCNA,RFC3,RAD18,RBX1,RPS27A,MRPS26,DNAJA1,SOX4,RFC2,DDB1,RPA1 |
| 1.573e-03 | -6.46 | REACTOME_SIGNALLING_TO_ERKS | MSigDB lists | REACTOME_SIGNALLING_TO_ERKS | 36 | 13 | 17377 | 2626 |
RAP1A,NRAS,SHC1,RALB,MAPKAPK3,RAF1,KRAS,RIT1,MAPK1,MAPK14,HRAS,MAP2K2,MAPK3 |
| 1.573e-03 | -6.46 | cortical actin cytoskeleton organization | biological process | GO:0030866 | 40 | 14 | 17256 | 2622 |
CDK5,WAS,PDCD6IP,STRIP1,WIPF1,KIF23,EZR,RACGAP1,NCKAP1,VPS4A,ROCK1,ANLN,RTKN,EPB41 |
| 1.575e-03 | -6.45 | lysophosphatidic acid acyltransferase activity | molecular function | GO:0042171 | 20 | 9 | 17224 | 2647 |
AGPAT2,LPCAT4,AGPAT1,AGPAT3,MBOAT1,LCLAT1,LPCAT1,TAZ,ABHD5 |
| 1.575e-03 | -6.45 | lysophospholipid acyltransferase activity | molecular function | GO:0071617 | 20 | 9 | 17224 | 2647 |
AGPAT2,LPCAT4,AGPAT1,AGPAT3,MBOAT1,LCLAT1,LPCAT1,TAZ,ABHD5 |
| 1.576e-03 | -6.45 | response to nerve growth factor | biological process | GO:1990089 | 53 | 17 | 17256 | 2622 |
PDPK1,KAT2A,CIB1,RPL8,FOXO3,APP,EEF2K,RAP1A,EIF4A3,PTEN,RAB35,E2F1,CORO1A,CREB1,CSNK1D,DYNC1LI2,CDC5L |
| 1.576e-03 | -6.45 | postreplication repair | biological process | GO:0006301 | 53 | 17 | 17256 | 2622 |
RFC3,POLK,USP10,UBE2V1,BRCA1,RFC2,MAD2L2,NEXMIF,NPLOC4,ISG15,RPA1,RPA2,DTL,PCNA,RAD18,RPS27A,MSH2 |
| 1.576e-03 | -6.45 | ARHGAP22 (Rho GTPase activating protein 22) | protein interactions | 58504 | 30 | 12 | 17029 | 2761 |
RAE1,ANK3,PPP3R1,PIP4K2C,CREB1,DOCK11,ERI3,CSNK1A1,ATF2,ARMC8,PDCD2L,PIP4K2A |
| 1.576e-03 | -6.45 | DLK2 (delta like non-canonical Notch ligand 2) | protein interactions | 65989 | 30 | 12 | 17029 | 2761 |
ZDHHC18,RABGAP1L,TYW1,LRBA,LRRC8A,TNPO2,SLC22A23,XPO7,LCLAT1,STAT3,APP,ASPHD2 |
| 1.576e-03 | -6.45 | GPR52 (G protein-coupled receptor 52) | protein interactions | 9293 | 30 | 12 | 17029 | 2761 |
ALG3,ERMP1,GPR89A,LMBR1,AGPAT3,SLC4A2,CHPT1,LCLAT1,REEP5,POT1,EBP,TMEM179B |
| 1.576e-03 | -6.45 | DDX51 (DEAD-box helicase 51) | protein interactions | 317781 | 30 | 12 | 17029 | 2761 |
ZNF512,RBM34,MECP2,NOL8,MYO18A,PCGF6,EFL1,KIF11,GAR1,CCDC59,RBM4,IFI16 |
| 1.576e-03 | -6.45 | SEPT10 (septin 10) | protein interactions | 151011 | 30 | 12 | 17029 | 2761 |
YTHDC1,SEPT1,SEPT9,TRIM11,CORO1C,MRPL12,CUL3,SEPT8,SEPT11,LSM8,SEPT7,ANLN |
| 1.576e-03 | -6.45 | USP45 (ubiquitin specific peptidase 45) | protein interactions | 85015 | 30 | 12 | 17029 | 2761 |
ERCC1,POLR2G,SAFB,RBMX,CORO1C,MYH9,SMAD1,PPP5C,SMURF1,SF3A2,MYL12B,ZFR |
| 1.579e-03 | -6.45 | SANA_RESPONSE_TO_IFNG_DN | MSigDB lists | SANA_RESPONSE_TO_IFNG_DN | 81 | 23 | 17377 | 2626 |
H2AFZ,NQO1,XAB2,UQCR10,RHOC,RPL6,TPX2,SSR2,NDUFA4,ARHGDIB,OAT,EIF4G2,ODC1,PRDX1,TFRC,RPSA,PA2G4,PON2,TIMM17A,EI24,METTL9,CABLES1,HDAC2 |
| 1.579e-03 | -6.45 | GO_POST_GOLGI_VESICLE_MEDIATED_TRANSPORT | MSigDB lists | GO_POST_GOLGI_VESICLE_MEDIATED_TRANSPORT | 81 | 23 | 17377 | 2626 |
CCDC93,RAB14,GCC2,CORO7,SCAMP3,SYS1,GOPC,ANK3,VTI1A,CHIC2,TGOLN2,RAB3IP,ARF1,MACF1,OPTN,GOLGA4,GOLGA7,KLHL20,NSF,SNAP23,DNM2,RP2,MYO5A |
| 1.579e-03 | -6.45 | GO_N_ACETYLTRANSFERASE_ACTIVITY | MSigDB lists | GO_N_ACETYLTRANSFERASE_ACTIVITY | 81 | 23 | 17377 | 2626 |
NAT14,NAT9,GNPNAT1,KAT2A,KAT7,ELP4,TAF6L,EDF1,USP22,SUPT7L,WDR5,SAP130,OGT,NAA50,TAF5L,NCOA1,TAF12,NAA20,SMARCE1,ATF2,SAT2,NAA60,NCOA2 |
| 1.580e-03 | -6.45 | positive regulation of intracellular protein transport | biological process | GO:0090316 | 150 | 37 | 17256 | 2622 |
UBE2D3,TM9SF4,PRKAA1,ANK3,CIB1,PRKACA,SEC16A,MAPK14,PSEN1,BCAP31,PRNP,MIEF1,KIF5B,CDK5,PDCD10,MDM2,HUWE1,PIK3R2,GTSE1,ATG13,MAVS,HTRA2,CHP1,TGFB1,PLK3,AKT2,NUTF2,EDEM2,TRIM28,USP36,SH3GLB1,PCM1,OAZ2,RUFY3,MAPK1,C2CD5,OAZ1 |
| 1.585e-03 | -6.45 | MKI67 (marker of proliferation Ki-67) | protein interactions | 4288 | 50 | 17 | 17029 | 2761 |
PPIB,NIFK,TK1,MECP2,SUMO2,MKI67,KIF15,SMC6,BRCA1,MCM2,LMNA,CAND1,CBX3,SYNCRIP,ECPAS,ABI1,IFI16 |
| 1.585e-03 | -6.45 | GDI2 (GDP dissociation inhibitor 2) | protein interactions | 2665 | 50 | 17 | 17029 | 2761 |
UNK,RAB8A,SKA3,RAB24,RAB11B,HUWE1,DUT,RAB7A,RAB4A,EZR,H2AFY,RAB1A,MCM2,STMN1,SMURF1,RAB11A,ISG15 |
| 1.585e-03 | -6.45 | DIMT1 (DIM1 dimethyladenosine transferase 1 homolog) | protein interactions | 27292 | 50 | 17 | 17029 | 2761 |
CYLD,USP42,BRCA1,ORC1,ABCF1,APP,FKBP3,RPL23A,CAND1,EIF3K,HNRNPA2B1,PTPN2,PA2G4,ZNF746,YBX1,TARDBP,DDX52 |
| 1.585e-03 | -6.45 | WDR61 (WD repeat domain 61) | protein interactions | 80349 | 50 | 17 | 17029 | 2761 |
PPP2CA,PAF1,DNAJC2,SARNP,BIRC3,UCHL5,PTPN11,CTR9,RTF1,TCEA1,WDR5,ATP6V1B2,HEXA,MCPH1,SMURF1,CDC73,IFI16 |
| 1.585e-03 | -6.45 | TOR1AIP1 (torsin 1A interacting protein 1) | protein interactions | 26092 | 50 | 17 | 17029 | 2761 |
TXN,PIGT,SEPT9,HPDL,TMEM216,NARF,NIT2,LMNA,EVC2,TERF2IP,CHCHD3,NDUFV1,KLHL15,HNRNPM,IPO4,IFI16,TERF2 |
| 1.585e-03 | -6.45 | Samm50 (SAMM50 sorting and assembly machinery component) | protein interactions | 68653 | 50 | 17 | 17029 | 2761 |
TAF2,CHCHD3,CCT2,IMMT,DGCR8,PRDX3,CLK3,PRDX5,MYH9,CAPZA2,ERBIN,FXR1,TAF6,CCT8,RPA1,EBP,SPTAN1 |
| 1.590e-03 | -6.44 | GSE26488_WT_VS_VP16_TRANSGENIC_HDAC7_KO_DOUBLE_POSITIVE_THYMOCYTE_DN | MSigDB lists | GSE26488_WT_VS_VP16_TRANSGENIC_HDAC7_KO_DOUBLE_POSITIVE_THYMOCYTE_DN | 156 | 38 | 17377 | 2626 |
UBE2E2,GOLIM4,PLXNC1,CREBL2,BZW2,PIP4K2A,GNS,HERC3,CAPN2,PA2G4,THADA,RALB,RPL19,BCAP29,LDLRAD3,GM2A,MICAL3,PDLIM2,CYFIP1,PTPN18,AATF,ATXN1,ARHGEF12,FOXRED1,RPS9,ABHD5,RPL37,WDR11,RPL32,RPS14,PRPS2,TFDP1,ATF6,ST3GAL2,RUFY3,USP11,CD81,PDCD2L |
| 1.596e-03 | -6.44 | CHD-type complex | cellular component | GO:0090545 | 17 | 8 | 18223 | 2701 |
CSNK2A1,RBBP4,CHD3,MBD3,APPL1,MTA2,HDAC2,APPL2 |
| 1.596e-03 | -6.44 | NuRD complex | cellular component | GO:0016581 | 17 | 8 | 18223 | 2701 |
CSNK2A1,RBBP4,CHD3,MBD3,APPL1,MTA2,HDAC2,APPL2 |
| 1.597e-03 | -6.44 | JDOMAIN | prints domains | PR00625 | 40 | 11 | 4652 | 473 |
DNAJC10,DNAJC8,DNAJC5,DNAJB2,DNAJC17,DNAJC24,DNAJC9,DNAJA1,DNAJB1,DNAJC30,DNAJB9 |
| 1.601e-03 | -6.44 | ACTGTGA,MIR-27A,MIR-27B | MSigDB lists | ACTGTGA,MIR-27A,MIR-27B | 442 | 90 | 17377 | 2626 |
AGRN,ARID2,WDTC1,SLC39A13,STARD7,PLAGL2,UBE2Q1,MAPK14,ZADH2,REPS1,NEK6,CDC42,BRPF3,MTMR4,PPME1,SOCS6,PDS5B,CABLES2,CTDSP2,ZNF800,DVL2,RLIM,RYBP,CLCN3,BTG2,HNRNPF,SREK1,UBE2V1,MIER2,GALNT7,CADM1,STX16,CBFB,PDHX,RAD54B,SRSF1,EPB41,DOT1L,SPATA2,LIMK1,RNF38,CAB39,NCOA1,H3F3A,B4GALT3,ABCA1,NXT2,POU3F2,RMND5A,TMUB1,EYA1,CCM2,MED13L,ARGLU1,UBE4A,DCUN1D4,RGS1,NDUFS4,GNS,GOLM1,CCNK,IRF4,RPN1,EIF2S2,RNFT1,MBD2,RIMS3,CAPZA1,SS18L1,GLTP,CREB1,LPCAT1,PDPK1,GCC2,ELL2,USP42,PSMA1,FAM133B,KDM3A,ARMC8,MOSPD3,TSC1,SERTAD2,ZHX1,ELMO1,CSNK1G1,FAM126A,RUFY3,PDLIM5,RNF139 |
| 1.606e-03 | -6.43 | UBIQUITIN_2 | prosite domains | PS50053 | 53 | 16 | 12060 | 1670 |
UBL3,UBQLN4,TMUB1,SUMO2,NFATC2IP,HERPUD2,USP48,UBQLN2,ISG15,UBLCP1,RAD23A,SNRNP25,RPS27A,RAD23B,UHRF2,FAU |
| 1.611e-03 | -6.43 | TFPT (TCF3 fusion partner) | protein interactions | 29844 | 76 | 23 | 17029 | 2761 |
CCDC93,MAX,RPRD1A,TCF3,RCOR1,NUF2,PAWR,EAF2,INO80E,PSMD9,GIT2,APP,HMG20A,OIP5,GRIPAP1,UCHL5,RABGAP1L,CDCA7L,ARNTL,C4orf46,RUVBL2,YY1,SGF29 |
| 1.611e-03 | -6.43 | WDR26 (WD repeat domain 26) | protein interactions | 80232 | 76 | 23 | 17029 | 2761 |
GID8,RMND5A,NDUFA5,MKLN1,PIGT,AKT2,RAE1,TIGD5,RPS24,NFATC2,WDR5,ARMC8,KCMF1,PIP4K2A,PNO1,RAB8A,AXIN1,MAPK6,ARRB2,ECPAS,RPS26,FAF1,HTRA2 |
| 1.611e-03 | -6.43 | RPRD1A (regulation of nuclear pre-mRNA domain containing 1A) | protein interactions | 55197 | 76 | 23 | 17029 | 2761 |
CCDC93,MAX,EWSR1,POLR2G,POLR2D,RCOR1,NUF2,BRCA1,PSMD9,PITHD1,GIT2,HMG20A,NPLOC4,SH3GLB1,OIP5,GRIPAP1,RABGAP1L,ARNTL,YWHAZ,TTLL12,MCMBP,ASB6,RPRD1B |
| 1.613e-03 | -6.43 | GSE1432_CTRL_VS_IFNG_1H_MICROGLIA_UP | MSigDB lists | GSE1432_CTRL_VS_IFNG_1H_MICROGLIA_UP | 177 | 42 | 17377 | 2626 |
USP7,IER2,DBF4,RAB23,DNAJC24,SDHA,GNB2,CD320,PHC2,KDM2A,DNAAF2,FAM89B,CRY2,AHCY,TMEM8A,LMAN1,NAA35,ILKAP,GCC1,PLK3,CDKN2AIP,BRD4,TSTA3,TUBGCP5,ZNF574,MEF2D,PLEC,MBD3,TOLLIP,GINS4,VEZF1,UPF1,MID1IP1,SH3GLB2,VPS4A,PPP5C,USP11,MAPK1,USF2,CBX4,B4GALT2,PTOV1 |
| 1.613e-03 | -6.43 | GSE11864_UNTREATED_VS_CSF1_IFNG_PAM3CYS_IN_MAC_DN | MSigDB lists | GSE11864_UNTREATED_VS_CSF1_IFNG_PAM3CYS_IN_MAC_DN | 177 | 42 | 17377 | 2626 |
BCL2L12,IMMT,GPR132,NUP188,SCAMP3,SEC61G,C1orf112,TMEM41B,KCTD17,CHIC2,RMI1,QSOX2,HLA-A,ZNF804A,SLC1A4,ZNF302,DAD1,FJX1,ZNF746,POP7,TXLNA,CTR9,CLDND1,CYB5R1,ATF2,FTL,PSMA1,GORASP2,ZNF407,IWS1,PI4K2A,UTP20,SEC61A1,GRIPAP1,ACOX1,ADAM9,BAZ1B,SNRPG,NR2F2,RNF14,ZNF75A,NXT2 |
| 1.613e-03 | -6.43 | GSE2770_TGFB_AND_IL4_ACT_VS_ACT_CD4_TCELL_48H_DN | MSigDB lists | GSE2770_TGFB_AND_IL4_ACT_VS_ACT_CD4_TCELL_48H_DN | 177 | 42 | 17377 | 2626 |
NAT14,DNMT3A,CDC40,ANXA6,BABAM1,TMX4,ABHD14B,KCMF1,CPNE3,NDUFS7,ADD3,MZT2A,ARF5,ANP32A,MRPL48,MRPL40,GPD1L,TMEM14C,TACC3,MLST8,TRIM8,HEBP2,IL12RB1,MTX1,ESYT1,NDUFB1,ASB13,MPG,PSMB9,NDRG3,HMGN2,GNAS,UBTF,CCDC6,TMEM219,FN3KRP,RBMS1,WDR91,CHPT1,SAT2,NMD3,NUDT3 |
| 1.617e-03 | -6.43 | nuclear ubiquitin ligase complex | cellular component | GO:0000152 | 41 | 14 | 18223 | 2701 |
PHC2,CDC16,BABAM2,CDC27,RBX1,PCGF6,ANAPC7,ANAPC2,BRCA1,CDC23,UBE2C,CBX4,MAD2L2,ANAPC4 |
| 1.618e-03 | -6.43 | SNRPB2 (small nuclear ribonucleoprotein polypeptide B2) | protein interactions | 6629 | 85 | 25 | 17029 | 2761 |
ZNF207,SNRNP200,CYLD,SF3B1,SF3B6,MRPL12,DHX9,CUL3,CUL1,SND1,SF3A2,CPNE3,SF3B2,HNRNPA2B1,SUGP1,PA2G4,DNAJC8,GOLGA2,EIF4A3,CS,ANXA5,PRPF4,GPI,SNRPG,SNRNP70 |
| 1.618e-03 | -6.43 | EVC2 (EvC ciliary complex subunit 2) | protein interactions | 132884 | 85 | 25 | 17029 | 2761 |
ANKLE2,NDC1,NSDHL,TOR1AIP1,ACSL3,MOGS,NUP155,CLCC1,ESYT1,BCAP31,DDRGK1,SEC11A,RPN1,PLD3,HSPBP1,MAGT1,BANF1,AHCY,SMPD4,SPCS3,YWHAH,TMX1,PREB,NUDC,CDC37 |
| 1.624e-03 | -6.42 | GO_PROTEIN_DESTABILIZATION | MSigDB lists | GO_PROTEIN_DESTABILIZATION | 32 | 12 | 17377 | 2626 |
DERL1,PLK1,MDM2,SIAH1,PRKDC,NCLN,TMEM147,FBXL3,CDC73,RNF139,RNF5,CDKN2A |
| 1.624e-03 | -6.42 | GO_MATURATION_OF_SSU_RRNA_FROM_TRICISTRONIC_RRNA_TRANSCRIPT_SSU_RRNA_5_8S_RRNA_LSU_RRNA_ | MSigDB lists | GO_MATURATION_OF_SSU_RRNA_FROM_TRICISTRONIC_RRNA_TRANSCRIPT_SSU_RRNA_5_8S_RRNA_LSU_RRNA_ | 32 | 12 | 17377 | 2626 |
UTP20,UTP18,RPS14,TBL3,RPS24,UTP3,RRS1,TSR2,RPSA,BYSL,RRP36,KRR1 |
| 1.624e-03 | -6.42 | BIOCARTA_AT1R_PATHWAY | MSigDB lists | BIOCARTA_AT1R_PATHWAY | 32 | 12 | 17377 | 2626 |
CALM2,SHC1,RAF1,RAC1,MEF2A,MEF2D,ELK1,MAPK1,ATF2,HRAS,MAP2K2,MAPK3 |
| 1.624e-03 | -6.42 | GO_NEGATIVE_REGULATION_OF_CYCLIN_DEPENDENT_PROTEIN_KINASE_ACTIVITY | MSigDB lists | GO_NEGATIVE_REGULATION_OF_CYCLIN_DEPENDENT_PROTEIN_KINASE_ACTIVITY | 32 | 12 | 17377 | 2626 |
PLK1,TFAP4,HHEX,TNFAIP3,PTEN,FBXO7,CUL3,CDKN1B,NR2F2,MEN1,UBE2C,CDKN2A |
| 1.624e-03 | -6.42 | REACTOME_TRANSPORT_OF_MATURE_MRNA_DERIVED_FROM_AN_INTRONLESS_TRANSCRIPT | MSigDB lists | REACTOME_TRANSPORT_OF_MATURE_MRNA_DERIVED_FROM_AN_INTRONLESS_TRANSCRIPT | 32 | 12 | 17377 | 2626 |
NUP188,NUP210,RAE1,NUP107,NUP54,NUP62,NUP155,NUP153,NUP85,SEH1L,AAAS,NUP205 |
| 1.624e-03 | -6.42 | GO_CELLULAR_RESPONSE_TO_DSRNA | MSigDB lists | GO_CELLULAR_RESPONSE_TO_DSRNA | 32 | 12 | 17377 | 2626 |
HNRNPA2B1,SMAD2,DGCR8,RALB,FLOT1,IRF3,MAVS,PRKRA,SMAD1,METTL3,SRRT,ZC3HAV1 |
| 1.625e-03 | -6.42 | GSE40274_CTRL_VS_FOXP3_AND_SATB1_TRANSDUCED_ACTIVATED_CD4_TCELL_UP | MSigDB lists | GSE40274_CTRL_VS_FOXP3_AND_SATB1_TRANSDUCED_ACTIVATED_CD4_TCELL_UP | 151 | 37 | 17377 | 2626 |
NOP2,SUZ12,TMEM41B,TMEM97,NUP54,HMGN3,MIS12,CFLAR,LYAR,GART,UCHL5,RBM34,UBA5,TAF5L,APOOL,ZRANB1,LRRC59,SYTL3,NXT1,ERLIN1,NOL8,UTP15,TUFM,SLBP,CDCA2,MRPS14,PRDX1,MYO1F,PSMC4,NFIL3,STX18,CDCA5,ITGB1,SLC25A19,RUFY3,SLC25A33,CSNK1D |
| 1.625e-03 | -6.42 | histone methyltransferase complex | cellular component | GO:0035097 | 73 | 21 | 18223 | 2701 |
MAX,ZFP64,SUZ12,CXXC1,TEX10,WDR82,EZH1,WDR5,KMT2C,MEN1,PAGR1,USF1,EPOP,PRDM4,ZNF335,KMT2B,H2AFY,RUVBL2,RBBP4,TAF6,HDAC2 |
| 1.625e-03 | -6.42 | Signaling Pathways in Glioblastoma | WikiPathways | WP2261 | 83 | 24 | 5312 | 837 |
PDPK1,NRAS,TSC2,NF1,RAF1,AKT2,KRAS,BRCA1,FOXO3,MAP2K2,MAPK3,CDKN2C,RB1,TSC1,MDM2,PTEN,PIK3R2,E2F1,CDKN1B,MAPK1,CDK2,HRAS,CDKN2A,MSH6 |
| 1.627e-03 | -6.42 | protein exit from endoplasmic reticulum | biological process | GO:0032527 | 24 | 10 | 17256 | 2622 |
DERL1,SEC61B,SURF4,MIA2,SEL1L,SYVN1,LMAN1,RHBDD1,NPLOC4,PREB |
| 1.627e-03 | -6.42 | negative regulation of DNA recombination | biological process | GO:0045910 | 24 | 10 | 17256 | 2622 |
TERF2IP,THOC1,KLHL15,HELB,PARPBP,MSH2,BLM,MSH6,TERF2,POLQ |
| 1.627e-03 | -6.42 | REACTOME_FORMATION_OF_TRANSCRIPTION_COUPLED_NER_TC_NER_REPAIR_COMPLEX | MSigDB lists | REACTOME_FORMATION_OF_TRANSCRIPTION_COUPLED_NER_TC_NER_REPAIR_COMPLEX | 28 | 11 | 17377 | 2626 |
ERCC1,POLR2I,POLR2G,POLR2L,POLR2J,POLR2K,XAB2,POLR2D,TCEA1,GTF2H2,POLR2A |
| 1.627e-03 | -6.42 | REACTOME_PKB_MEDIATED_EVENTS | MSigDB lists | REACTOME_PKB_MEDIATED_EVENTS | 28 | 11 | 17377 | 2626 |
TSC1,PRKAB1,TSC2,AKT2,PRKAA1,CAB39,STK11,PDE3B,RHEB,MLST8,EEF2K |
| 1.627e-03 | -6.42 | MODULE_77 | MSigDB lists | MODULE_77 | 28 | 11 | 17377 | 2626 |
NDUFA5,NDUFV2,NDUFV1,NDUFA2,NDUFA4,NDUFS8,NDUFS5,NDUFA7,NDUFB1,NDUFA3,NDUFS4 |
| 1.636e-03 | -6.42 | rRNA modification in the nucleus and cytosol | REACTOME pathways | R-HSA-6790901 | 62 | 20 | 10287 | 1696 |
DDX47,RPS2,NOP2,UTP15,BMS1,UTP3,GAR1,RPS9,RRP36,KRR1,UTP25,UTP20,NOL11,UTP18,TBL3,RPS14,FBL,PDCD11,UTP4,DDX52 |
| 1.638e-03 | -6.41 | anaplastic | COSMIC cancer mutations | anaplastic | 17 | 8 | 17385 | 2587 |
CDKN2C,KRAS,NRAS,PTEN,HRAS,SMAD4,AXIN1,CDKN2A |
| 1.638e-03 | -6.41 | pineal_gland | COSMIC cancer mutations | pineal_gland | 17 | 8 | 17385 | 2587 |
KRAS,EWSR1,NRAS,H3F3A,HRAS,CDKN2A,MSH6,MSH2 |
| 1.638e-03 | -6.41 | central_nervous_system-optic_nerve-glioma-astrocytoma_Grade_I | COSMIC cancer mutations | central_nervous_system-optic_nerve-glioma-astrocytoma_Grade_I | 17 | 8 | 17385 | 2587 |
KRAS,NRAS,NF1,PTEN,HRAS,CDKN2A,PTPN11,CLCN6 |
| 1.638e-03 | -6.41 | optic_nerve | COSMIC cancer mutations | optic_nerve | 17 | 8 | 17385 | 2587 |
KRAS,NRAS,NF1,PTEN,HRAS,CDKN2A,PTPN11,CLCN6 |
| 1.639e-03 | -6.41 | PID_FOXO_PATHWAY | MSigDB lists | PID_FOXO_PATHWAY | 49 | 16 | 17377 | 2626 |
CAT,USP7,PLK1,CSNK1G2,RALB,CSNK1G1,CDKN1B,YWHAZ,CCNB1,CDK2,ZFAND5,YWHAH,CSNK1A1,FOXO3,CSNK1D,CSNK1G3 |
| 1.639e-03 | -6.41 | GO_POSTREPLICATION_REPAIR | MSigDB lists | GO_POSTREPLICATION_REPAIR | 49 | 16 | 17377 | 2626 |
RFC3,POLK,USP10,UBE2V1,BRCA1,RFC2,MAD2L2,NPLOC4,ISG15,RPA1,RPA2,DTL,PCNA,RAD18,RPS27A,MSH2 |
| 1.639e-03 | -6.41 | GO_PROTEIN_MONOUBIQUITINATION | MSigDB lists | GO_PROTEIN_MONOUBIQUITINATION | 49 | 16 | 17377 | 2626 |
DTL,UBE2D3,FANCL,PAF1,RAD18,RBX1,HUWE1,CUL3,CUL1,CTR9,TOPORS,UBE4B,PCGF1,CDC73,DDB1,RYBP |
| 1.639e-03 | -6.41 | REACTOME_SCF_BETA_TRCP_MEDIATED_DEGRADATION_OF_EMI1 | MSigDB lists | REACTOME_SCF_BETA_TRCP_MEDIATED_DEGRADATION_OF_EMI1 | 49 | 16 | 17377 | 2626 |
PSMA8,PSMB7,PSMA1,CUL1,PSMB9,PSMD9,PSMB3,PSMC4,FBXO5,PSMD2,PSMA6,PSMD1,RPS27A,PSMD3,PSMD8,PSMC1 |
| 1.640e-03 | -6.41 | SASSON_RESPONSE_TO_FORSKOLIN_UP | MSigDB lists | SASSON_RESPONSE_TO_FORSKOLIN_UP | 86 | 24 | 17377 | 2626 |
RAB14,ACP2,TNFAIP3,SMARCA4,EZR,JMJD6,CREBL2,RAB1A,BECN1,MAP1LC3B,MAPK14,ARPC1A,RHOB,CFLAR,GNAS,PSMD1,ATP2A2,DUSP3,MBD2,RAB4A,PGRMC1,FKBP5,PDXK,MAP3K5 |
| 1.642e-03 | -6.41 | GSE26669_CTRL_VS_COSTIM_BLOCK_MLR_CD4_TCELL_UP | MSigDB lists | GSE26669_CTRL_VS_COSTIM_BLOCK_MLR_CD4_TCELL_UP | 193 | 45 | 17377 | 2626 |
DDX58,HIVEP3,NOP2,TAP1,CIB1,OLA1,AGPAT3,POMP,SND1,EIF1B,WDR48,PSMD1,GART,SAR1A,BANF1,BUD31,TAP2,DNMT1,TIMM50,PTPRK,METTL1,NXT1,IDH3A,UTP15,ADSL,MRPS10,AURKB,PRKRA,GSTCD,ASB13,CCT8,AMZ2,INF2,TRAM2,NUCB1,CCDC6,RBMX,NSMCE2,PML,NLRC5,USP32,CHMP4B,GPI,UBE2C,GCSH |
| 1.642e-03 | -6.41 | GSE21360_NAIVE_VS_QUATERNARY_MEMORY_CD8_TCELL_UP | MSigDB lists | GSE21360_NAIVE_VS_QUATERNARY_MEMORY_CD8_TCELL_UP | 193 | 45 | 17377 | 2626 |
DDX58,CMAS,PARP12,BZW2,CDC73,PNO1,MIS12,CREM,C1GALT1,SLC31A1,HOMER1,SP100,WDR44,IMPAD1,ZNHIT6,ZCCHC2,DCP1A,INTS12,BCAP29,EIF5,NIPAL3,SLC39A9,IFRD1,ETV3,SNX2,LAP3,COQ10B,IDH3A,DENND1B,NOL8,MRS2,GALNT7,ARMC8,MAK16,ISG15,DTWD1,PALB2,FBXO28,TIMM17A,TBPL1,VCPIP1,AEN,EHD4,XRCC4,TMEM33 |
| 1.642e-03 | -6.41 | GSE41978_WT_VS_ID2_KO_AND_BIM_KO_KLRG1_LOW_EFFECTOR_CD8_TCELL_DN | MSigDB lists | GSE41978_WT_VS_ID2_KO_AND_BIM_KO_KLRG1_LOW_EFFECTOR_CD8_TCELL_DN | 193 | 45 | 17377 | 2626 |
PLXNC1,MECP2,FAM53C,MUM1,XIAP,FAM76A,KIF23,RACGAP1,GLUD1,RGS2,STMN1,CPNE3,LMNA,SPAG5,UBLCP1,EEF2K,FANCL,C1GALT1,ZNF746,CLCN6,KIFAP3,APOOL,ZC3H3,DNAL4,PHF20L1,CSRP1,PPT1,WDHD1,NFATC2IP,ASF1B,TBC1D17,RBL1,MFAP1,NEIL3,STX18,CEP55,MYO18A,ARNTL,BCL7C,GALNT10,SMAD1,EHD4,UBE2C,ABCA1,SMARCD1 |
| 1.642e-03 | -6.41 | GSE43955_TH0_VS_TGFB_IL6_IL23_TH17_ACT_CD4_TCELL_52H_UP | MSigDB lists | GSE43955_TH0_VS_TGFB_IL6_IL23_TH17_ACT_CD4_TCELL_52H_UP | 193 | 45 | 17377 | 2626 |
RMND5A,HSPH1,PKP4,FOXM1,ARID2,MEF2A,ATP6V1B2,MAPK14,GGPS1,LYRM2,REPS1,TFRC,RNF103,NUS1,AXIN2,CS,TAGLN2,CORO1A,TCEA1,SLC26A2,LRRC59,FGFR1OP2,TMX1,SPTAN1,TRAFD1,ACP2,NUDT4,PPP1R21,NSUN2,EMP3,WDR82,MAP4K3,ELK1,EIF4H,API5,MAK16,MARK2,NCDN,HSPA1B,RDH11,AMZ2,OSBPL11,ARNTL,DBI,TOB1 |
| 1.644e-03 | -6.41 | ITGB3BP (integrin subunit beta 3 binding protein) | protein interactions | 23421 | 46 | 16 | 17029 | 2761 |
CCNA2,DDX24,DGCR8,MCM5,MTA1,MECP2,MAPK6,ARFIP2,COG1,CENPT,ATP5MF,ATP5PF,ITGB5,APP,C2CD5,CENPU |
| 1.644e-03 | -6.41 | AURKAIP1 (aurora kinase A interacting protein 1) | protein interactions | 54998 | 46 | 16 | 17029 | 2761 |
MRPS2,NOA1,ZFP91,MRS2,CUL3,MRPS10,CSNK2A1,NAP1L1,DAP3,STRBP,HNRNPR,MRPS27,MRPL40,CDK2,NSUN4,GEMIN7 |
| 1.644e-03 | -6.41 | CENPF (centromere protein F) | protein interactions | 1063 | 46 | 16 | 17029 | 2761 |
MZT1,FOXM1,GOPC,NQO2,CENPF,BRAP,BRCA1,CHMP2B,CENPU,FNTA,CDCA5,NUP107,COPS6,ARRB2,TERF1,TERF2 |
| 1.644e-03 | -6.41 | Cdc16 (CDC16 cell division cycle 16) | protein interactions | 69957 | 46 | 16 | 17029 | 2761 |
SCAMP3,CUL1,RRM2,SLC25A22,ANAPC2,CDC23,FBXO5,HOMER1,CDC16,KIF18A,CLIC4,CDC27,NDUFB4,ANAPC7,TAP2,ANAPC4 |
| 1.644e-03 | -6.41 | CASP10 (caspase 10) | protein interactions | 843 | 46 | 16 | 17029 | 2761 |
OIP5,RB1,PHF20L1,RHOA,BIRC3,CASP6,XIAP,EZR,MAP3K14,BIRC2,CCAR1,FADD,POLR2A,CFLAR,RYBP,FAS |
| 1.644e-03 | -6.41 | Snu13 (SNU13 homolog, small nuclear ribonucleoprotein (U4/U6.U5)) | protein interactions | 20826 | 46 | 16 | 17029 | 2761 |
SNRPB,DHX9,HNRNPF,SNRPD3,GAR1,DHX15,PABPC4,KPNA1,ZNHIT6,TARDBP,KPNA2,RUVBL2,FBL,PABPC1,COIL,GPATCH4 |
| 1.644e-03 | -6.41 | MAPRE2 (microtubule associated protein RP/EB family member 2) | protein interactions | 10982 | 46 | 16 | 17029 | 2761 |
MAPRE2,MAPRE1,TCTEX1D2,POC1A,AURKB,LRRC1,APP,LMNA,CEP104,SMC3,HUWE1,DGCR8,DNAAF2,CENPJ,CDK2,DCTN1 |
| 1.646e-03 | -6.41 | BRCA1-associated genome surveillance complex (BASC) | KEGG pathways | M00295 | 16 | 8 | 7161 | 1149 |
RFC3,BRCA1,PCNA,BLM,RFC2,MSH6,PMS2,MSH2 |
| 1.646e-03 | -6.41 | BRCA1-associated genome surveillance complex (BASC) | KEGG pathways | hsa_M00295 | 16 | 8 | 7161 | 1149 |
RFC3,BRCA1,PCNA,BLM,RFC2,MSH6,PMS2,MSH2 |
| 1.651e-03 | -6.41 | MRE11 (MRE11 homolog, double strand break repair nuclease) | protein interactions | 4361 | 127 | 34 | 17029 | 2761 |
FGFR1OP,SUMO2,DHX9,BLM,LMNA,TERF2IP,HNRNPA2B1,RPA2,MDM2,HUWE1,RTCB,MSH2,ATF2,MSH6,TACC3,HNRNPM,TERF2,CDC5L,GINS1,GCC2,PRKDC,NFATC2,DCLRE1C,BRCA1,PCGF1,MCM2,ABCF1,RPA1,NEK1,QARS,ODF2,H2AFX,UHRF2,USP11 |
| 1.653e-03 | -6.41 | histone deacetylase activity | molecular function | GO:0004407 | 44 | 15 | 17224 | 2647 |
BRMS1,CHD3,HDAC7,MTA1,MTA2,MIER1,RCOR1,MIER2,SIRT2,RBBP4,MBD3,SAP30L,ARID4A,HDAC2,SAP30 |
| 1.655e-03 | -6.40 | transferrin transport | biological process | GO:0033572 | 36 | 13 | 17256 | 2622 |
ATP6V0B,ATP6V1D,RAB11B,DNM2,ATP6V0A2,ATP6V0A1,ATP6V0C,ATP6V1C1,ATP6V1B2,ATP6V0D1,ATP6V0E1,TFRC,ATP6V1G1 |
| 1.658e-03 | -6.40 | MCM3AP (minichromosome maintenance complex component 3 associated protein) | protein interactions | 8888 | 34 | 13 | 17029 | 2761 |
IER2,POLR2G,SUV39H2,CDC42,FAM118B,RAC1,TMEM216,BLM,DDX39A,CDC73,IFI16,LMNA,TERF2 |
| 1.658e-03 | -6.40 | GFER (growth factor, augmenter of liver regeneration) | protein interactions | 2671 | 34 | 13 | 17029 | 2761 |
COPS8,TXN,SMAD2,KLHL20,THAP4,WDYHV1,PMF1,FAM136A,MAPK14,PCBP1,GFER,TUBB,PLEKHF2 |
| 1.658e-03 | -6.40 | RPP30 (ribonuclease P/MRP subunit p30) | protein interactions | 10556 | 34 | 13 | 17029 | 2761 |
PTPN2,INTS2,RPP25,PSMA6,HUWE1,POP7,CUL3,KIF15,CBWD1,CARMIL1,HMG20A,IFI16,CAND1 |
| 1.658e-03 | -6.40 | PROSER2 (proline and serine rich 2) | protein interactions | 254427 | 34 | 13 | 17029 | 2761 |
YTHDC1,CDKN2C,CTU2,SNX27,PDCD10,DHPS,ANK3,ACTB,SLC25A43,APP,POT1,CSNK1G3,IPO4 |
| 1.658e-03 | -6.40 | UTP4 (UTP4, small subunit processome component) | protein interactions | 84916 | 34 | 13 | 17029 | 2761 |
ANKRD28,GOLGA4,VASP,NOL11,UTP15,CERK,KIF22,BRCA1,FBL,APP,IFI16,ISG15,PRNP |
| 1.660e-03 | -6.40 | cytosolic transport | biological process | GO:0016482 | 130 | 33 | 17256 | 2622 |
RAB14,ANKRD27,CORO7,SYS1,VTI1A,ZFYVE21,TGOLN2,RAB6A,BECN1,RIC1,HEATR5B,KLHL20,TBC1D14,CORO1A,PIKFYVE,LMAN1,DCTN1,SRSF10,SNX8,GCC2,RHOBTB3,SNX2,RAB7A,WDR81,STX16,GOSR1,ERC1,TBC1D17,SURF4,VPS26B,AP1S1,WDR91,VPS29 |
| 1.661e-03 | -6.40 | SAP | prosite domains | PS50800 | 22 | 9 | 12060 | 1670 |
SARNP,RAD18,SAFB,HNRNPUL2,PIAS2,SAFB2,SLTM,CCAR1,SF3B2 |
| 1.661e-03 | -6.40 | DEAH_ATP_HELICASE | prosite domains | PS00690 | 22 | 9 | 12060 | 1670 |
DHX16,CHD3,DHX29,CHD1L,DHX9,DHX8,BLM,DHX57,DHX15 |
| 1.661e-03 | -6.40 | ATACCTC,MIR-202 | MSigDB lists | ATACCTC,MIR-202 | 172 | 41 | 17377 | 2626 |
SNX27,ZBTB10,SMAP1,MED13L,IP6K2,DCUN1D4,DNAJB9,CREM,DST,RB1,ASAP2,INPP5A,SEC24C,ADCY9,PIK3IP1,FBXL19,SCYL3,ARL5A,MOB4,GABPA,KIAA0040,NEK7,BTG2,KIAA0930,MTMR12,MIER2,RHOT1,ARMC8,DPYSL3,KIF2A,NAP1L1,SERTAD2,KPNA4,GALNT2,TAB2,CSNK1G1,LUC7L3,RNF139,CPEB2,ATXN7L2,STARD3NL |
| 1.661e-03 | -6.40 | GSE6092_IFNG_VS_IFNG_AND_B_BURGDORFERI_INF_ENDOTHELIAL_CELL_UP | MSigDB lists | GSE6092_IFNG_VS_IFNG_AND_B_BURGDORFERI_INF_ENDOTHELIAL_CELL_UP | 172 | 41 | 17377 | 2626 |
MIB2,TSC22D3,CERK,EZH1,GYG1,RGS2,DUSP22,PIP4K2A,XPR1,STRBP,NEK6,GOT2,IL6ST,KIF13B,SOCS6,FNIP2,MAVS,CYB5R1,TMEM8A,TPCN1,CTDSP2,MOSPD1,ALDH9A1,HP1BP3,SNX8,MBLAC2,NQO2,ATP6V0A1,POLG2,GNA12,FBXO21,DUSP3,FAM3C,NAGLU,APPL2,PDXK,LTA4H,CD81,RAD51D,RAB3IL1,AAAS |
| 1.664e-03 | -6.40 | FULCHER_INFLAMMATORY_RESPONSE_LECTIN_VS_LPS_UP | MSigDB lists | FULCHER_INFLAMMATORY_RESPONSE_LECTIN_VS_LPS_UP | 523 | 104 | 17377 | 2626 |
NQO1,CKLF,IVNS1ABP,FAM129A,MYH9,TBC1D13,NENF,CDC42SE2,SND1,DUSP22,SLC20A1,POLR3K,EEF2K,ABL2,PRKD3,NEK6,IARS,TBC1D22A,GOT2,SLC44A1,TTC9C,METTL9,MINPP1,LMAN1,AHCYL1,RHBDD2,ACSL5,PLK3,SLC39A9,SNX8,POLR2G,BIRC3,FOPNL,BTG2,LYRM1,SOX4,EDEM2,PEF1,EML4,KIF2A,BOLA3,HINT1,CERS6,LIMK1,HIPK2,PPA2,H2AFX,ST3GAL2,FKBP5,RRS1,LRP8,NMD3,NDUFV2,AGTRAP,RHOC,TCF3,UBXN1,GADD45G,SDC2,SUMF1,GTF3A,TMED3,BZW2,MAD2L2,RGS1,SRXN1,KIF5B,IRF4,SUB1,VASP,NUS1,NDUFA2,DAD1,FAM89B,ORAI1,ANP32A,NDUFS8,GLTP,TAGLN2,MYO5A,ABCC1,PPP3CA,ABHD2,ETV3,CSRP1,MAPKAPK3,NET1,DENND1B,ATP2C1,ACSL3,MFNG,JTB,SSR2,STYXL1,FADD,YIF1A,SH3BP5,MTHFD2,ETS2,CSK,DTX4,KHSRP,MAP3K5,PTDSS1 |
| 1.664e-03 | -6.40 | Integrated Pancreatic Cancer Pathway | WikiPathways | WP2377 | 197 | 47 | 5312 | 837 |
RAF1,RAC1,PTTG1,RRM1,ARF1,BLM,MAPK14,STMN1,APP,FKBP1A,MDM2,PCNA,RAP1A,CCNA2,PTEN,CDKN1B,BCL2,TP53BP2,CREB1,TGFB1,PLK1,FTL,RB1CC1,NCK1,KRAS,BRCA1,FKBP3,FADD,RHEB,MAPK3,FAS,MAP3K4,SMAD2,AGPAT2,RBL1,E2F4,E2F1,STAT1,PML,CAB39,STK11,CHEK2,MAP3K5,MAPK1,CDK2,SMAD4,CAPN1 |
| 1.664e-03 | -6.40 | NFKBIA (NFKB inhibitor alpha) | protein interactions | 4792 | 156 | 40 | 17029 | 2761 |
UBE2D3,CTU2,NCOR2,ANKRD27,ATXN3,GNPNAT1,RPS6KA1,DYNLL1,CENPF,CUL1,CSNK2A1,CHAC2,UBE2I,SPDL1,CSNK1A1,MAPK14,BIRC2,NPLOC4,MCTS1,CAPN2,RNF121,MCM5,PIN1,MAVS,TCEA1,MAP3K14,COPS8,RHOA,DCAF6,PSMA1,ARMT1,SLC25A5,ERC1,POLR2A,POLR2J,STAT1,CLU,ARRB2,HDAC2,CAPN1 |
| 1.667e-03 | -6.40 | N-glycosylation by oligosaccharyltransferase | KEGG pathways | M00072 | 7 | 5 | 7161 | 1149 |
RPN2,RPN1,DDOST,STT3A,DAD1 |
| 1.667e-03 | -6.40 | N-glycosylation by oligosaccharyltransferase | KEGG pathways | hsa_M00072 | 7 | 5 | 7161 | 1149 |
RPN2,RPN1,DDOST,STT3A,DAD1 |
| 1.670e-03 | -6.40 | SAP | pfam domains | PF02037 | 17 | 8 | 17054 | 2545 |
SARNP,RAD18,SAFB,HNRNPUL2,SAFB2,SLTM,CCAR1,SF3B2 |
| 1.674e-03 | -6.39 | ARF5 (ADP ribosylation factor 5) | protein interactions | 381 | 63 | 20 | 17029 | 2761 |
UNK,STAU1,RHOBTB3,GGA1,VDAC2,LDHA,ARFIP2,TGOLN2,ARF1,AP1B1,DUSP22,RAB5B,FAS,ASAP2,ACADM,RNF26,CLN3,PCBP2,LDHB,CDC5L |
| 1.674e-03 | -6.39 | DYRK1B (dual specificity tyrosine phosphorylation regulated kinase 1B) | protein interactions | 9149 | 63 | 20 | 17029 | 2761 |
FOXK1,FAM53C,DYNLL1,KIAA0232,PRKACA,MAPK14,RB1,CCNA2,RBL1,HIPK2,ARNTL,ICE2,PTGES3,TECR,USP11,GLCCI1,MAPK1,RNF169,DDB1,CDKN2A |
| 1.674e-03 | -6.39 | PARD6A (par-6 family cell polarity regulator alpha) | protein interactions | 50855 | 63 | 20 | 17029 | 2761 |
RPAP3,ARHGAP17,ASH1L,VHL,NOL8,RAC1,PMS2,SMARCA4,GLUD1,MARK2,APP,CDC42,PRDX3,PDRG1,YWHAZ,TTC3,TP53BP2,YWHAH,SMURF1,PARD3 |
| 1.674e-03 | -6.39 | PC (pyruvate carboxylase) | protein interactions | 5091 | 63 | 20 | 17029 | 2761 |
DYNLL1,MDH2,RAB7A,NACA,TUFM,ILF3,ADRB2,GNB2,WWP2,RPN1,KPNA4,ATP1A1,PTEN,HUWE1,GOT2,ZNF746,CBWD1,XRCC3,RPN2,STRAP |
| 1.675e-03 | -6.39 | Citric acid cycle (TCA cycle) | REACTOME pathways | R-HSA-71403 | 19 | 9 | 10287 | 1696 |
SDHB,SUCLG1,MDH2,IDH3A,CS,SUCLG2,OGDH,IDH3B,SDHA |
| 1.675e-03 | -6.39 | Phosphorylation of the APC/C | REACTOME pathways | R-HSA-176412 | 19 | 9 | 10287 | 1696 |
PLK1,CDC16,CDC27,ANAPC2,ANAPC7,CCNB1,CDC23,UBE2C,ANAPC4 |
| 1.680e-03 | -6.39 | low_malignant_potential_(borderline)_tumour | COSMIC cancer mutations | low_malignant_potential_(borderline)_tumour | 41 | 14 | 17385 | 2587 |
GNAS,FGFR3,RB1,NRAS,JAK1,PTEN,SF3B1,GOPC,KRAS,BRCA1,ARID1A,SMAD4,HRAS,CDKN2A |
| 1.681e-03 | -6.39 | SS18L1 (SS18L1, nBAF chromatin remodeling complex subunit) | protein interactions | 26039 | 42 | 15 | 17029 | 2761 |
SKA3,AATF,SNRPB,PCGF6,CUL3,MIA2,SMARCA4,NSD3,SS18L1,SMAD1,SMARCE1,STAT3,HDAC2,RLIM,SMARCD1 |
| 1.681e-03 | -6.39 | ELP3 (elongator acetyltransferase complex subunit 3) | protein interactions | 55140 | 42 | 15 | 17029 | 2761 |
CTDP1,FGFR1OP,PCNA,SNRNP200,PCGF6,ELP4,SMC6,SMAD1,PCGF1,MPG,ANLN,SMURF1,POLR2A,SSSCA1,WRNIP1 |
| 1.681e-03 | -6.39 | ID3 (inhibitor of DNA binding 3, HLH protein) | protein interactions | 3399 | 42 | 15 | 17029 | 2761 |
TCF12,UNK,MLX,ADD1,CSK,VHL,E2F4,TCF3,CBFA2T2,ELK1,CDK2,GNB2,IFI16,CNOT3,SAP30 |
| 1.681e-03 | -6.39 | DNAJB2 (DnaJ heat shock protein family (Hsp40) member B2) | protein interactions | 3300 | 42 | 15 | 17029 | 2761 |
RFWD3,CYHR1,NSMCE4A,HSPA4,CYLD,ATXN3,PSMA6,RPS27A,CSNK2A1,ASNA1,TARDBP,CTSA,SMAD4,BIRC2,RLIM |
| 1.681e-03 | -6.39 | Rrp1b (ribosomal RNA processing 1 homolog B (S. cerevisiae)) | protein interactions | 72462 | 42 | 15 | 17029 | 2761 |
LYAR,ERH,STAU1,DDX47,LUC7L3,SRSF6,ILF3,MKI67,CDCA8,DNAJC9,LRRC59,TRIM28,LUC7L2,SRSF1,PRPF4B |
| 1.681e-03 | -6.39 | CAPRIN1 (cell cycle associated protein 1) | protein interactions | 4076 | 42 | 15 | 17029 | 2761 |
RPA2,STAU1,CYLD,PIN1,CIRBP,CUL3,CUL1,YBX1,TARDBP,BRCA1,FXR1,CDK2,APP,RPA1,CAND1 |
| 1.681e-03 | -6.39 | CSTF1 (cleavage stimulation factor subunit 1) | protein interactions | 1477 | 42 | 15 | 17029 | 2761 |
HSPBP1,DNAAF5,RRM2,RACGAP1,TARDBP,NFATC2,BRCA1,MPG,PARN,TOLLIP,NDRG3,NMD3,POLR2A,MAPK3,CSTF1 |
| 1.683e-03 | -6.39 | GO_PHOSPHATASE_ACTIVITY | MSigDB lists | GO_PHOSPHATASE_ACTIVITY | 247 | 55 | 17377 | 2626 |
CTDP1,PPP1R12A,EYA1,PPP1R15B,PTP4A3,CYCS,PPP3CB,EPHX2,DUSP22,EPM2A,UBLCP1,PTPN2,PPP1R3B,PDXP,PTEN,INPP5A,NT5DC1,MTMR4,IMPAD1,LPIN2,PPP4R1,PPP6C,PTPN11,CDC25B,PIKFYVE,MINPP1,ILKAP,HDHD2,CTDSP2,CAMK2G,IMPA2,TIMM50,PTPRK,NTPCR,PPP3CA,PTPN18,ACP2,MTMR6,PFKFB3,STYXL1,PPP2CA,MTMR3,PTPRF,ATP1A1,DUSP3,PPM1G,PPA2,PPP3R1,PTPN7,DUSP11,PTPDC1,NANP,PPP5C,PGAM1,EYA2 |
| 1.687e-03 | -6.38 | CAGCAGG,MIR-370 | MSigDB lists | CAGCAGG,MIR-370 | 141 | 35 | 17377 | 2626 |
DNMT3A,MAPRE1,HNRNPAB,ANK3,ARF1,FBRS,CCNK,NFATC3,JAZF1,PPIL2,TAP2,FAM76B,STAT3,NSUN4,CFL1,SRSF11,PHF20L1,BAZ2A,ZMYND11,TAOK1,ILF3,E2F3,VDAC2,ATXN1,PBRM1,RAB3IP,BRCA1,NCDN,DHX57,TMEM127,DUSP3,ZC3H7B,OGT,PDCD11,SMARCD1 |
| 1.689e-03 | -6.38 | TDP2 (tyrosyl-DNA phosphodiesterase 2) | protein interactions | 51567 | 38 | 14 | 17029 | 2761 |
ETS2,GORASP1,SUMO2,MAPK6,TAP1,WBP2,ATXN1,UBE2I,PSEN1,ETS1,TRAF5,RAB11A,PARK7,SRPK2 |
| 1.689e-03 | -6.38 | PPIL3 (peptidylprolyl isomerase like 3) | protein interactions | 53938 | 38 | 14 | 17029 | 2761 |
COX5B,SYNCRIP,FAM49B,SEC24C,RAD23B,PSMA1,RPAP1,WDR82,TAGLN2,AHCYL1,PCBP1,IGBP1,GINS4,GLOD4 |
| 1.698e-03 | -6.38 | GSE17721_POLYIC_VS_GARDIQUIMOD_6H_BMDC_UP | MSigDB lists | GSE17721_POLYIC_VS_GARDIQUIMOD_6H_BMDC_UP | 188 | 44 | 17377 | 2626 |
PRPF38B,DNMT3A,FEZ2,DNAJC5,MCM10,CHTF18,MRPL39,TOR3A,PTTG1,NOTCH2,GGA2,CSNK1A1,FOXO3,CMTM6,CPNE3,RGS1,TFAP4,HOMER1,PCNA,HDAC7,PPIG,TPST1,CDKN1B,TIMELESS,TFG,AHCYL1,CTDSP2,MORC3,BRD4,EID1,DNAJA1,KLF6,ZFAND5,PLEKHF2,EPB41,LIMK1,TFDP1,IMPDH1,NAA20,BRWD3,PDLIM5,SMAD4,TOB1,RNF114 |
| 1.698e-03 | -6.38 | GSE39820_CTRL_VS_TGFBETA3_IL6_CD4_TCELL_UP | MSigDB lists | GSE39820_CTRL_VS_TGFBETA3_IL6_CD4_TCELL_UP | 188 | 44 | 17377 | 2626 |
SARNP,GSPT2,BZW2,MOAP1,RFWD3,RPA2,STARD9,RPN1,CTSS,MCM5,AKAP8,RCSD1,NUP107,PTPN11,RPF2,CISD2,CITED2,C12orf75,NUP85,SOCS5,PPAN,PPP3CA,ERMP1,ELL2,TLK1,TBRG4,DNAJA1,DIDO1,TXNL4A,FKBP3,TSR2,TWISTNB,SH3BP5,UTP20,PTER,ITGB1,LRPPRC,AEN,SLC16A1,BEND3,CD81,GPATCH4,HDAC2,SVIP |
| 1.698e-03 | -6.38 | GSE22611_NOD2_VS_CTRL_TRANSDUCED_HEK293T_CELL_DN | MSigDB lists | GSE22611_NOD2_VS_CTRL_TRANSDUCED_HEK293T_CELL_DN | 188 | 44 | 17377 | 2626 |
NDUFB6,UBR2,TSC22D3,FAM53C,RAF1,TMX4,TKT,RGS2,TWF2,RAB11A,FOXO3,SLC25A37,DNAAF2,ETV6,PHTF1,DAPK1,OSTF1,CORO1A,CEP63,TACC3,CAMK2G,ABCC5,ADCY7,AMPD2,PGAP2,IFRD1,ELOVL5,TRIM8,ZNF500,LDHA,NARF,FRAT2,TOPORS,ARHGDIB,PLEC,MTX1,ZNF407,RFC2,ABCF1,HHEX,HSPB11,SCAP,RBPJ,PDSS2 |
| 1.698e-03 | -6.38 | GSE3039_ALPHAALPHA_CD8_TCELL_VS_B1_BCELL_DN | MSigDB lists | GSE3039_ALPHAALPHA_CD8_TCELL_VS_B1_BCELL_DN | 188 | 44 | 17377 | 2626 |
TMUB1,MCM10,FOXM1,RAF1,TCF3,PTTG1,SLC35B2,BLM,APH1B,OIP5,INTS7,HDAC7,NUP107,AP1M1,ZFYVE27,CTR9,COPS7B,PCYT2,ZRANB1,ABCC5,LDHB,CSTF1,FDFT1,COPS8,MND1,MAPKAPK3,RAD51AP1,VHL,WBP2,PKMYT1,OTUD3,RFC2,RAD54B,MASTL,TFEB,SLCO4A1,SERF2,RAD18,E2F1,ARRDC1,NCLN,MBD6,RUVBL2,CENPT |
| 1.698e-03 | -6.38 | GSE17721_CTRL_VS_PAM3CSK4_24H_BMDC_DN | MSigDB lists | GSE17721_CTRL_VS_PAM3CSK4_24H_BMDC_DN | 188 | 44 | 17377 | 2626 |
PPIB,TMED7,GOLIM4,HJURP,NQO1,UGP2,DHPS,MRPL39,FAM129A,RBM8A,SMARCA4,BCL2L1,SNRPD3,REPS1,C14orf119,KRI1,CDK5,DLG5,SLC31A1,ATP6V0B,EIF2S2,CBWD2,DDA1,PTPN11,DAPK1,MRPL54,OSTF1,MRPL11,LRRC59,SMARCE1,CFL1,CSTF1,LARS,RRM2,BCLAF1,CYFIP2,PRDX1,PSMC4,RBM47,ORMDL2,NIP7,RWDD4,ATE1,SSSCA1 |
| 1.698e-03 | -6.38 | GSE43863_TFH_VS_LY6C_LOW_CXCR5NEG_EFFECTOR_CD4_TCELL_UP | MSigDB lists | GSE43863_TFH_VS_LY6C_LOW_CXCR5NEG_EFFECTOR_CD4_TCELL_UP | 188 | 44 | 17377 | 2626 |
DDX58,HECA,PARP12,TMEM184B,FAM129A,TAP1,MYEF2,CPNE3,TMCC3,KIF5B,RAB8A,BDH1,FUT8,ZDHHC13,BCL2,AQR,ZRANB1,PIKFYVE,TFG,SMARCE1,MCMBP,MYO5A,SOCS5,SRSF11,B3GALT6,TRAFD1,IDH3A,GOPC,TOR1AIP2,USP22,PSMB9,STK17B,OPTN,UAP1,TMEM168,CDC27,MFAP1,SNAP23,GADD45B,BBX,STAT1,PML,BEND3,RNF114 |
| 1.698e-03 | -6.38 | GSE30962_ACUTE_VS_CHRONIC_LCMV_SECONDARY_INF_CD8_TCELL_DN | MSigDB lists | GSE30962_ACUTE_VS_CHRONIC_LCMV_SECONDARY_INF_CD8_TCELL_DN | 188 | 44 | 17377 | 2626 |
FGFR1OP,MCM10,CLSPN,RRM1,TPX2,STMN1,PMVK,PIP4K2A,TFRC,TMCC3,DTL,DUT,PRC1,BTF3L4,KIF22,BCAP29,C12orf75,PPA1,TMBIM1,TACC3,GINS1,TK1,NASP,PBK,RAD51AP1,PSMB7,LDHA,RRM2,CKAP2L,SMC2,BRCA1,GAR1,SHCBP1,HHEX,LSM6,BIRC5,TWSG1,ZNF367,FAM3C,E2F1,COX5A,EHD4,CD81,GCSH |
| 1.698e-03 | -6.38 | GSE5589_LPS_VS_LPS_AND_IL6_STIM_MACROPHAGE_45MIN_UP | MSigDB lists | GSE5589_LPS_VS_LPS_AND_IL6_STIM_MACROPHAGE_45MIN_UP | 188 | 44 | 17377 | 2626 |
EWSR1,CKLF,AGRN,ZCCHC8,MAGED1,CCM2,PPP3CB,TWF2,STARD9,VASP,CENPJ,PHF14,ADCY9,GLTP,UPF2,UBE3B,RNF135,TMEM9,MED22,NIPSNAP1,USP34,KDM3B,FAM49B,ERLIN1,HSDL1,ATXN1,NFATC2,WDR81,WBP1,FXR1,KLF6,MTR,KEAP1,SURF4,UAP1,TFE3,HAGHL,CTSA,SCARB1,PDXK,MAP3K5,GLCCI1,MRPL3,PTOV1 |
| 1.698e-03 | -6.38 | GSE22601_DOUBLE_NEGATIVE_VS_CD4_SINGLE_POSITIVE_THYMOCYTE_UP | MSigDB lists | GSE22601_DOUBLE_NEGATIVE_VS_CD4_SINGLE_POSITIVE_THYMOCYTE_UP | 188 | 44 | 17377 | 2626 |
WASF2,EWSR1,WDYHV1,DAP,TSC22D3,TAP1,MXD4,RGS2,ZADH2,COMMD8,CCDC28A,KIAA1147,SEC11A,PTEN,HDAC7,TTC3,CDC25B,PIK3IP1,TECR,FRMD8,MGAT5,SMC4,FDFT1,SAP30,TGFB1,PPP3CA,BTG2,ATXN1,PDE3B,RBM38,ARHGAP15,RHOB,GNAS,HLA-B,VEZF1,STK38,CDCA5,FAM3C,APPL2,C4orf46,SCARB1,RNASEL,NGLY1,TOB1 |
| 1.698e-03 | -6.38 | GSE31082_DP_VS_CD4_SP_THYMOCYTE_DN | MSigDB lists | GSE31082_DP_VS_CD4_SP_THYMOCYTE_DN | 188 | 44 | 17377 | 2626 |
MIF,HIVEP3,AGRN,WDYHV1,PRKAA1,TAP1,SLC25A12,KLHL18,SMC6,NKRF,NOTCH2,PABPC4,KRI1,NUP210,RIMS3,SRI,RPN2,TMEM8A,FRMD8,RPL22L1,TRIM14,KCNAB2,MED22,ABHD2,PTPN18,TIMP2,MAPKAPK3,KIAA0040,USP42,GTPBP4,SLC26A6,CYP20A1,LRRC8A,RTF1,MAPK3,ABHD5,XRCC5,RPL37,SH3BP5,TRIM26,SEC61A1,LRPPRC,RRS1,CBX4 |
| 1.698e-03 | -6.38 | GSE3982_CTRL_VS_IGE_STIM_MAST_CELL_UP | MSigDB lists | GSE3982_CTRL_VS_IGE_STIM_MAST_CELL_UP | 188 | 44 | 17377 | 2626 |
MUT,TSC2,UFC1,RRM1,TM9SF3,SMARCA4,SLC20A1,REEP5,NFATC3,DNAJC8,CTNNBL1,HUWE1,ATG3,IL6ST,TNPO3,ZC3H3,S100A6,MOSPD1,TXNL1,SRSF11,PHF10,ELOVL5,MLEC,MAPKAPK3,CREG1,PBXIP1,LRBA,METTL5,ELP4,CADM1,API5,DTWD1,DNAJC10,ELMO1,OSBPL8,CSNK1G1,STK38,RPS14,STAT6,C1orf109,PML,QRSL1,BTF3,ATP6V0E1 |
| 1.698e-03 | -6.38 | GSE40666_WT_VS_STAT1_KO_CD8_TCELL_WITH_IFNA_STIM_90MIN_DN | MSigDB lists | GSE40666_WT_VS_STAT1_KO_CD8_TCELL_WITH_IFNA_STIM_90MIN_DN | 188 | 44 | 17377 | 2626 |
DNMT3A,H2AFZ,MCM10,CLSPN,CDCA8,BLM,TCF19,MFSD10,TFRC,MXD1,LMNA,OIP5,PCNA,MCM5,JAZF1,KNTC1,CENPM,N4BP2,TRAFD1,RFC3,TK1,E2F3,RRM2,CKAP2L,TOR1AIP2,CDC6,UBE4B,SMC2,SOX4,SHCBP1,RFC2,CBFB,ASF1B,AKAP1,POLE,BIRC5,CDCA5,PML,E2F1,RWDD4,SMPD4,CDK2,RTN3,TUBB |
| 1.698e-03 | -6.38 | GSE27786_BCELL_VS_MONO_MAC_DN | MSigDB lists | GSE27786_BCELL_VS_MONO_MAC_DN | 188 | 44 | 17377 | 2626 |
RHOG,PRKAB1,PDCD6IP,HJURP,PPP1R15B,PCSK7,MAN2B1,ARF1,PSEN1,FBXO3,VASP,LRRC8D,CRAT,PRC1,RP2,ACAD8,CITED2,CNNM3,ATP6V0D1,PACS2,TACC3,CAMK2G,PTPRK,AMPD2,PHF10,CREG1,PBXIP1,ASPM,RAD51AP1,CCDC34,PKMYT1,PRKRA,API5,OPTN,MID1IP1,MTHFD2,SERF2,RBM47,RAB24,TFE3,CORO1C,SASS6,MZT2B,NAA60 |
| 1.698e-03 | -6.38 | MORF4L2 (mortality factor 4 like 2) | protein interactions | 9643 | 99 | 28 | 17029 | 2761 |
ZBTB10,ASH1L,BRCA1,BLM,H2AFV,MEAF6,LMNA,RPA1,PHC2,RPA2,RB1,KPNA1,HSPA4,SYNCRIP,PALB2,GOLGA2,HNRNPR,L3MBTL3,JAZF1,EXOSC1,CEP55,PITPNA,KPNA2,MRFAP1L1,ACTB,RUVBL2,HNRNPM,HDAC2 |
| 1.701e-03 | -6.38 | HMGB1 (high mobility group box 1) | protein interactions | 3146 | 113 | 31 | 17029 | 2761 |
CTDP1,EWSR1,AGTRAP,ERF,PRKDC,MECP2,CTCF,SMARCA4,CSNK1A1,PSEN1,SUPT16H,TERF2IP,TFAP4,RB1,SP100,HUWE1,TFE3,RAD23B,XPA,DNM2,HMGB2,RBPJ,WDR76,H3F3A,CDK2,MAPK1,SMARCE1,DNMT1,TERF2,SSRP1,SMARCD1 |
| 1.701e-03 | -6.38 | ZF_PHD_2 | prosite domains | PS50016 | 73 | 20 | 12060 | 1670 |
PHF10,KMT2E,BAZ2A,PHRF1,CXXC1,ZMYND11,NSD3,DIDO1,KMT2C,TRIM28,SP100,BRPF3,KDM2A,CHD3,PHF14,UHRF2,KMT2B,BAZ1B,INTS12,FBXL19 |
| 1.703e-03 | -6.38 | The oncogenic action of 2-hydroxyglutarate | SMPDB pathways | SMP02291 | 26 | 11 | 992 | 167 |
SDHB,KDM2A,SUCLG1,IDH3A,MDH2,CS,SUCLG2,OGDH,IDH3B,SDHA,MPC1 |
| 1.707e-03 | -6.37 | in utero embryonic development | biological process | GO:0001701 | 306 | 66 | 17256 | 2622 |
GGNBP2,ADD1,ADAM10,XAB2,WDTC1,MYH9,BCL2L1,CCNB1,RRN3,XRCC2,PRPF19,SP3,GABPA,CUL3,POLG2,MBD3,ZFAND5,TRIM28,GINS4,SRSF1,HHEX,SMAD2,ITGB1,BTF3,NCOA1,MAPK1,SMAD4,CCM2,EPN1,CNOT3,CAPN2,EIF2S2,SEC24C,DAD1,FUT8,MSH2,RTCB,ZNF335,CTR9,YBX1,TMED2,GINS1,NASP,KAT2A,NSDHL,RDH10,SF3B6,RTF1,ZP3,MFN2,TFEB,PSMC4,GNA12,KEAP1,PALB2,DUSP3,PKD2,RBPJ,ZNF830,ZMIZ1,NR2F2,PLOD3,CCNB2,BYSL,ALS2,EGLN1 |
| 1.707e-03 | -6.37 | GSE15330_MEGAKARYOCYTE_ERYTHROID_VS_GRANULOCYTE_MONOCYTE_PROGENITOR_UP | MSigDB lists | GSE15330_MEGAKARYOCYTE_ERYTHROID_VS_GRANULOCYTE_MONOCYTE_PROGENITOR_UP | 167 | 40 | 17377 | 2626 |
IER2,GMFG,FAM129A,SRGN,UFC1,PTTG1,HAUS4,SDF2L1,AP3S1,MAP1LC3B,REEP5,RGS1,NDUFS4,SSR1,RPA2,CAPN2,SUB1,CCDC50,INTS12,F2R,MTPN,SAP30,DDX28,NQO2,NUDT4,COQ10B,SCFD2,RHEB,ECH1,MYO1F,GLOD4,ABHD5,AHNAK,RBM47,NFIL3,ITGB1,ATF6,ATP6V0C,CHPT1,PFKP |
| 1.707e-03 | -6.37 | GO_REGULATION_OF_PROTEIN_BINDING | MSigDB lists | GO_REGULATION_OF_PROTEIN_BINDING | 167 | 40 | 17377 | 2626 |
MAPRE1,ADD1,FLOT1,PRKACA,PSEN1,APP,PARK7,CDK5,FKBP1A,CDC42,RALB,PIN1,GTSE1,BCL2,PLCL2,CARM1,BAK1,PLK1,GTPBP4,MFNG,PACS1,AURKB,ADRB2,MEN1,BTBD1,MAPK3,EPB41,KRIT1,PTPRF,DERL1,GOLGA2,HIPK2,PRMT7,TICAM1,ZNF268,ROCK1,DVL1,RUVBL2,ARRB2,SNAPIN |
| 1.707e-03 | -6.37 | GSE9988_ANTI_TREM1_AND_LPS_VS_CTRL_TREATED_MONOCYTES_UP | MSigDB lists | GSE9988_ANTI_TREM1_AND_LPS_VS_CTRL_TREATED_MONOCYTES_UP | 167 | 40 | 17377 | 2626 |
GCLM,TXN,GNPDA1,KLHL21,PPP1R15B,TFRC,RGS1,SPAG5,CFLAR,SRXN1,MOAP1,DTL,ABL2,RAB21,HOMER1,SNUPN,FNIP2,TP53BP2,N4BP2,RYBP,PLK3,TCTEX1D2,KLF10,COQ10B,ACSL3,RIT1,RAB1A,KLF6,ARL5B,NEU1,SLCO4A1,ETS2,MAFK,GADD45B,MAPK6,OGT,SIAH2,USP53,CCDC59,ZC3HC1 |
| 1.718e-03 | -6.37 | WCTCNATGGY_UNKNOWN | MSigDB lists | WCTCNATGGY_UNKNOWN | 72 | 21 | 17377 | 2626 |
IER2,ERCC1,PKP4,CHERP,ERF,C1orf112,PGS1,MRPS10,POLR3GL,RFFL,BRIX1,GALNT2,ATP6V1D,GPS2,ODF2,PHTF1,COX8A,YBX1,PRADC1,CHPF2,SMARCD1 |
| 1.719e-03 | -6.37 | cellular response to radiation | biological process | GO:0071478 | 161 | 39 | 17256 | 2622 |
TMEM109,BCL2L1,EIF2AK4,BLM,MAPK14,METTL3,RHBDD1,PCNA,MDM2,INTS7,TANK,XPA,NOC2L,DNM2,CRY2,SPIDR,EEF1D,PTPRK,BAK1,TGFB1,ERCC1,POLK,NET1,AKT2,PBK,RAD51AP1,AURKB,ELK1,RHOB,RDH11,XRCC5,H2AFX,STK11,RUVBL2,CHEK2,YY1,HRAS,IFI16,DDB1 |
| 1.737e-03 | -6.36 | regulation of telomerase activity | biological process | GO:0051972 | 49 | 16 | 17256 | 2622 |
CCT2,NEK7,PARP4,AURKB,MEN1,PARN,MAPK3,XRCC5,MAP3K4,HNRNPA2B1,NVL,NABP2,PTGES3,MAPK1,TERF1,POT1 |
| 1.749e-03 | -6.35 | GO_NEGATIVE_REGULATION_OF_PHOSPHATE_METABOLIC_PROCESS | MSigDB lists | GO_NEGATIVE_REGULATION_OF_PHOSPHATE_METABOLIC_PROCESS | 518 | 103 | 17377 | 2626 |
ZBED3,PPP1R37,FGFR1OP,ASH1L,TSC2,FOXM1,NF1,UBN1,DYNLL1,PPP1R15B,FAM129A,SIRT2,CCNB1,DUSP22,PPP1R16B,LYN,PARK7,PRNP,CALM2,CDKN2C,PIN1,SOCS6,CDKN1B,CRY2,TARDBP,GPD1L,STRAP,CTDSP2,ANKLE2,SNX25,PLK1,BAK1,PPIF,NCK1,PBK,CUL3,GMFB,EZR,LRP5,DNAJA1,PKMYT1,PRPSAP1,SOCS7,PPP2CA,DNAJC10,HHEX,PPP2R5A,STK38,CORO1C,GADD45B,SOCS4,OGT,ROCK1,DVL1,PPP5C,PDCD4,PARD3,HSPH1,ZCCHC9,GMFG,CIB1,AKT1S1,RGS2,PSEN1,PTPN2,FKBP1A,TFAP4,RB1,PTEN,FBXO7,H2AFY,PIK3IP1,MVP,GNAI2,STAT3,LPCAT1,SOCS5,PDPK1,TGFB1,TNFAIP3,PRKDC,ZMYND11,PRKAR1B,GBA,WDR81,MEN1,AKAP1,MASTL,LEMD2,SH3BP5,MBIP,CSK,DUSP3,PRDX3,GPS2,PPP1R11,NUP62,NR2F2,IGBP1,UBE2C,HIPK3,CDKN2A,EGLN1 |
| 1.749e-03 | -6.35 | GO_NEGATIVE_REGULATION_OF_PHOSPHORUS_METABOLIC_PROCESS | MSigDB lists | GO_NEGATIVE_REGULATION_OF_PHOSPHORUS_METABOLIC_PROCESS | 518 | 103 | 17377 | 2626 |
ZBED3,PPP1R37,FGFR1OP,ASH1L,TSC2,NF1,UBN1,FOXM1,DYNLL1,PPP1R15B,FAM129A,SIRT2,CCNB1,DUSP22,PPP1R16B,LYN,PARK7,PRNP,CALM2,CDKN2C,PIN1,SOCS6,CDKN1B,TARDBP,CRY2,GPD1L,STRAP,CTDSP2,ANKLE2,BAK1,PLK1,SNX25,PPIF,NCK1,PBK,CUL3,GMFB,EZR,LRP5,DNAJA1,PKMYT1,PRPSAP1,SOCS7,PPP2CA,DNAJC10,HHEX,PPP2R5A,CORO1C,STK38,GADD45B,SOCS4,OGT,ROCK1,DVL1,PPP5C,PDCD4,PARD3,HSPH1,ZCCHC9,GMFG,CIB1,AKT1S1,RGS2,PSEN1,FKBP1A,PTPN2,TFAP4,RB1,PTEN,FBXO7,H2AFY,PIK3IP1,MVP,LPCAT1,GNAI2,STAT3,SOCS5,TGFB1,PDPK1,TNFAIP3,PRKDC,ZMYND11,PRKAR1B,GBA,WDR81,MEN1,AKAP1,MASTL,SH3BP5,LEMD2,MBIP,PRDX3,GPS2,DUSP3,CSK,PPP1R11,NUP62,NR2F2,UBE2C,IGBP1,HIPK3,CDKN2A,EGLN1 |
| 1.750e-03 | -6.35 | primary active transmembrane transporter activity | molecular function | GO:0015399 | 124 | 32 | 17224 | 2647 |
TOMM20,ABCA3,SEC61G,ABCC10,TAP1,ABCB10,ATP5F1B,ATP6V1B2,ATP6V0B,ATP2A2,TIMM23,ATP13A3,ATP6V0A2,TAP2,ABCD1,ATP6V0D1,ABCC5,ABCC1,ATP6V1G1,ATP13A1,SEC61B,ATP2C1,ATP6V0A1,ATP1A1,ATP6V1D,ATP5MC3,TIMM17A,ATP6V0C,ATP5F1A,ATP6V1C1,ATP6V0E1,ABCA1 |
| 1.750e-03 | -6.35 | P-P-bond-hydrolysis-driven transmembrane transporter activity | molecular function | GO:0015405 | 124 | 32 | 17224 | 2647 |
TOMM20,ABCA3,SEC61G,ABCC10,TAP1,ABCB10,ATP5F1B,ATP6V1B2,ATP6V0B,ATP2A2,TIMM23,ATP13A3,ATP6V0A2,TAP2,ABCD1,ATP6V0D1,ABCC5,ABCC1,ATP6V1G1,ATP13A1,SEC61B,ATP2C1,ATP6V0A1,ATP1A1,ATP6V1D,ATP5MC3,TIMM17A,ATP6V0C,ATP5F1A,ATP6V1C1,ATP6V0E1,ABCA1 |
| 1.753e-03 | -6.35 | GSE14000_UNSTIM_VS_16H_LPS_DC_DN | MSigDB lists | GSE14000_UNSTIM_VS_16H_LPS_DC_DN | 183 | 43 | 17377 | 2626 |
PARP12,TRIP10,PPP1R15B,MECP2,PLAGL2,UBE2Z,TBC1D13,C2orf49,CDC73,CFLAR,SLC38A5,RABGAP1L,MBD2,GRSF1,TPST1,DCP1A,MRPL32,MKLN1,ETV3,ELL2,RBX1,KIAA0040,COQ10B,AMD1,MIER1,LDHA,PRPF3,NFATC2IP,LY6E,GOSR1,TARS,SMAP2,MASTL,TRIM26,GADD45B,PML,C4orf46,RUFY3,USP11,CDK2,USP53,APOL2,NXT2 |
| 1.753e-03 | -6.35 | GSE2770_TGFB_AND_IL4_ACT_VS_ACT_CD4_TCELL_48H_UP | MSigDB lists | GSE2770_TGFB_AND_IL4_ACT_VS_ACT_CD4_TCELL_48H_UP | 183 | 43 | 17377 | 2626 |
UNK,NDUFV2,GCLM,DYNLL1,ACTR3,LAMTOR3,POMP,ZNF267,ATP6V1B2,HLA-A,RPA2,IRF4,PSMD1,MED8,TNFAIP8,PELO,TANK,TXLNA,ZNF200,ZNF710,ABCC1,METTL1,GTF3C6,ADAM17,PPP1R18,CREG1,RAB7A,TEX10,PSMB7,PSMA1,DNAJA1,EML4,SH3GLB1,NEU1,POLR2A,C1orf122,HLA-B,MFAP1,MRPL27,PDXK,ATP6V1C1,PSMC1,ATP6V0E1 |
| 1.753e-03 | -6.35 | GSE12392_WT_VS_IFNB_KO_CD8A_POS_SPLEEN_DC_UP | MSigDB lists | GSE12392_WT_VS_IFNB_KO_CD8A_POS_SPLEEN_DC_UP | 183 | 43 | 17377 | 2626 |
CCDC93,PARP12,SUCLG1,PHB2,ARID2,FAM129A,TOR3A,TRIO,ASAH1,AGPAT3,TAF6L,FKBP2,AP3S1,ZADH2,SYNRG,RAB11A,PHC2,HADHB,MRPL54,OSTC,SLC35C2,TMBIM1,TMED2,CYTH1,SEPT9,SELPLG,DENND1B,USP22,GALNT7,TWISTNB,PI4K2A,MAP3K4,NUCB1,SCARB2,STT3A,LIMK1,MYO18A,OAZ2,GALNT10,SCARB1,MYO9A,ATP6V0E1,ESYT2 |
| 1.753e-03 | -6.35 | GSE17721_PAM3CSK4_VS_GADIQUIMOD_16H_BMDC_DN | MSigDB lists | GSE17721_PAM3CSK4_VS_GADIQUIMOD_16H_BMDC_DN | 183 | 43 | 17377 | 2626 |
MCM10,TRIP10,HLA-E,RHOC,DYNLL1,TOR3A,TOR1AIP1,PTTG1,ARID5A,C19orf25,AGFG1,POMP,ATP6V1B2,KIF5B,UTP18,FUT8,TARDBP,SMARCE1,ABI1,TMBIM1,TIMM50,SAP30,COPS8,RFC3,SNX2,NUDT4,MAP7D1,KRAS,SEPT7,TAZ,FKBP3,ISG15,PSMC4,CSK,SAFB,SOCS4,PRMT7,USP20,ATE1,ATF6,MRPL13,TSEN15,ATMIN |
| 1.753e-03 | -6.35 | GSE7831_UNSTIM_VS_INFLUENZA_STIM_PDC_1H_UP | MSigDB lists | GSE7831_UNSTIM_VS_INFLUENZA_STIM_PDC_1H_UP | 183 | 43 | 17377 | 2626 |
HIVEP3,PKP4,DEPDC1,UROD,CDK2AP2,GADD45G,CDCA8,AKT1S1,OAT,PMVK,ASXL2,POLR3K,EBP,C14orf119,DAD1,DDA1,XRCC2,KIF22,RNF26,F2R,SLC25A1,FDFT1,ABHD2,ELL2,NSDHL,SLC26A6,PSMB7,WIPF1,AURKB,SHCBP1,BORA,NECAP2,MAN2A2,NUCB1,GOLGA7,BIRC5,TPP2,COX5A,USP20,MDH1,CTSA,TMEM101,ATP6V0E1 |
| 1.753e-03 | -6.35 | GSE5589_IL6_KO_VS_IL10_KO_LPS_STIM_MACROPHAGE_45MIN_DN | MSigDB lists | GSE5589_IL6_KO_VS_IL10_KO_LPS_STIM_MACROPHAGE_45MIN_DN | 183 | 43 | 17377 | 2626 |
NADSYN1,PRPF38B,CASP6,EIF3D,UBXN1,MRPS26,NIPA2,ATP6V1B2,TMEM165,NDUFS7,RGS1,CD320,DDRGK1,MCTS1,TMEM179B,PTPN2,CSDE1,CLIC4,ITGB8,AHCYL1,TTPAL,LARS,SEPT9,KLF10,ELL2,NCK1,TSPAN31,PPP1R21,GORASP2,GALNT7,RPS9,HSPA1B,EIF3K,EPRS,SERTAD2,CERS6,HNRNPH3,LIMK1,SEL1L,PLOD3,LTA4H,CCDC59,ATMIN |
| 1.753e-03 | -6.35 | GSE23505_UNTREATED_VS_4DAY_IL6_IL1_IL23_TREATED_CD4_TCELL_UP | MSigDB lists | GSE23505_UNTREATED_VS_4DAY_IL6_IL1_IL23_TREATED_CD4_TCELL_UP | 183 | 43 | 17377 | 2626 |
TCF12,TBC1D12,MZT1,GMFG,CASP6,PRKAA1,RLF,NUS1,RBM34,TANK,FOXN2,EIF5,ATP6V0D1,SYTL3,CSNK1G3,RYBP,POU2AF1,IFRD1,CYTH1,ARHGAP17,BIRC3,AATF,GTPBP4,ILF3,WIPF1,EZR,MAP4K3,AZI2,CBFB,STK17B,SERP1,MAT2A,ARHGAP15,OPTN,HLA-B,VEZF1,CHD3,MAFK,FAM126A,GLCCI1,PTDSS1,RTN3,PURA |
| 1.753e-03 | -6.35 | GSE18791_CTRL_VS_NEWCASTLE_VIRUS_DC_18H_UP | MSigDB lists | GSE18791_CTRL_VS_NEWCASTLE_VIRUS_DC_18H_UP | 183 | 43 | 17377 | 2626 |
CDC40,PHB2,URB2,SLC25A12,IKBIP,IL21R,PPP1R16B,STAM,ATPAF1,XPR1,EDC3,ATG4A,FLAD1,CWC27,PHF14,EFTUD2,GEMIN6,GPATCH1,AHCY,CORO1A,SLC26A2,TNRC18,DNMT1,TSHZ1,ZNF559,POLR2L,POLR2G,MRPL12,MRPL16,MTMR12,ASB13,RPA1,FBXO21,IDE,NIP7,WNT5B,TFDP1,KBTBD7,PITPNA,FAM126A,OSGEPL1,RNF14,AP2S1 |
| 1.753e-03 | -6.35 | GSE17721_LPS_VS_CPG_4H_BMDC_DN | MSigDB lists | GSE17721_LPS_VS_CPG_4H_BMDC_DN | 183 | 43 | 17377 | 2626 |
POLA2,TCF12,CMAS,TMED7,NSMCE4A,GMFG,NOP2,SRSF6,CERK,DHX8,SMC6,TMED3,LACTB2,TWF2,SRXN1,C14orf119,HNRNPA2B1,SEC11A,RAP1A,IARS,STRBP,RNASEK,NSFL1C,FOXN2,MRPL11,EIF5,PDPK1,ADAM17,ACP2,FOPNL,NSDHL,POLR2D,GMFB,TOMM40,MCFD2,PEF1,DHX57,HINT1,CDCA5,MPV17,SLC25A19,KPNA2,PDF |
| 1.753e-03 | -6.35 | CAMP_UP.V1_UP | MSigDB lists | CAMP_UP.V1_UP | 183 | 43 | 17377 | 2626 |
PPIB,IVNS1ABP,MDH2,MAGED1,COPE,FLOT1,LETMD1,ARF1,PA2G4,RPN1,NDUFV1,NT5DC1,CS,AHCYL1,ANKHD1,TMEM9,CLPTM1,IFRD1,AATF,KIAA0040,NQO2,ZBED5,WBP1,SLC25A5,RHOT2,CHAF1A,DDX23,PRIM1,DAP3,MTHFD2,HSPBP1,ATP1A1,SEC61A1,ELMO1,ZNF367,COX8A,CEBPG,SIL1,HMGB2,SCARB1,SAT2,IPO4,AAAS |
| 1.753e-03 | -6.35 | GSE5589_LPS_AND_IL10_VS_LPS_AND_IL6_STIM_MACROPHAGE_45MIN_UP | MSigDB lists | GSE5589_LPS_AND_IL10_VS_LPS_AND_IL6_STIM_MACROPHAGE_45MIN_UP | 183 | 43 | 17377 | 2626 |
TCF12,NAT9,SMAP1,NF1,MRPS15,TMX4,NENF,EIF2AK4,HCFC1R1,ASXL2,FOXO3,PIP4K2A,TRIM65,RNF103,HEATR5B,ANKRD28,PPP1R3B,GATC,ZNF746,CDKN1B,ABCD1,PIKFYVE,ERI3,LRSAM1,TPCN1,PACS2,RNLS,SLC25A1,ABCC1,SPTAN1,SAMD4B,DENND4C,NEU1,RXRB,PEX5,GPS2,APPL2,TMEM159,TFDP2,ARHGAP23,MZT2B,SLC25A39,ATMIN |
| 1.753e-03 | -6.35 | GSE2770_TGFB_AND_IL4_VS_IL4_TREATED_ACT_CD4_TCELL_48H_UP | MSigDB lists | GSE2770_TGFB_AND_IL4_VS_IL4_TREATED_ACT_CD4_TCELL_48H_UP | 183 | 43 | 17377 | 2626 |
WSB2,ZNF207,PDCD6IP,EWSR1,MUT,DYNLL1,FAM129A,TRIO,LAMTOR3,RRAGC,PSEN1,PSMD1,TANK,TPST1,ZNF200,AKR1B1,FNIP2,ANAPC7,SLC26A2,ZNF189,ABCC1,ADAM17,SEC61B,ELL2,CREG1,WDR1,CRNKL1,LACTB,DNAJA1,RIT1,PNPLA8,TRIM28,POLR2A,TTLL4,MFAP1,HIPK2,HPS5,NUP62,ST3GAL2,PDXK,CD81,ATP6V0E1,STARD3NL |
| 1.753e-03 | -6.35 | GSE3920_UNTREATED_VS_IFNB_TREATED_ENDOTHELIAL_CELL_DN | MSigDB lists | GSE3920_UNTREATED_VS_IFNB_TREATED_ENDOTHELIAL_CELL_DN | 162 | 39 | 17377 | 2626 |
IMMT,ADD1,TSC2,TCF3,SLC25A12,SIKE1,TBC1D13,GMCL1,CLCC1,XPO7,NCAPG,COPG2,TRIM65,ZBTB45,CCNA2,ADD3,ZNRF2,PRC1,MSH2,CS,MTPN,TMX1,RPP25,TDP1,FOXK1,TSPYL4,ELP4,RRM2,ESYT1,MEN1,KIF11,RPA1,ZMYM3,AKAP1,TONSL,TFDP1,PPA2,SEL1L,GEN1 |
| 1.753e-03 | -6.35 | GSE17974_0.5H_VS_72H_UNTREATED_IN_VITRO_CD4_TCELL_UP | MSigDB lists | GSE17974_0.5H_VS_72H_UNTREATED_IN_VITRO_CD4_TCELL_UP | 162 | 39 | 17377 | 2626 |
CTU2,ZBTB10,RRP15,CAST,SRSF6,SRGN,DAZAP2,CHD1,JMY,DNAJB9,SYNM,TIMM23,ZNF326,JOSD1,TTC17,EIF5,NAGPA,CYTH1,PBXIP1,BTG2,AKT2,UTP15,CYP20A1,GORAB,TWISTNB,AKAP1,MTMR3,TSC1,SPATA2,ZHX1,L3MBTL3,TPP2,GADD45B,SLC22A23,PPP6R2,RNF139,SLC25A33,ADNP2,DDX52 |
| 1.754e-03 | -6.35 | LU_EZH2_TARGETS_DN | MSigDB lists | LU_EZH2_TARGETS_DN | 347 | 73 | 17377 | 2626 |
PIGM,MAGED1,NIPA2,NHLRC3,RUFY1,EXT2,BIRC2,PAIP1,MBD4,OIP5,ATP2A2,XRCC2,TAP2,MTPN,ABCC5,PBK,NSUN2,LRBA,PSMG1,WDHD1,MCL1,UTP3,ASB13,ANLN,CBFB,CHCHD3,TMED10,RNF38,CBLN2,CRCP,KPNA2,RNASEL,NUDT11,RTN3,LRP8,DYNC1LI2,POLQ,PRPF4B,ZCCHC9,ANKRD13D,TMX3,PM20D2,XPNPEP3,ETS1,RPA2,CTR9,CREB1,SGCB,N4BP2,NIPAL3,PPP3CA,TNFAIP3,ELL2,TACC1,BTAF1,ATP2C1,SUGP2,GORASP2,BCLAF1,CYFIP2,VKORC1,EIF4G2,PICALM,ANKRD46,NEU1,MAGED2,CDKN2AIPNL,MAGT1,TFDP1,FAM83D,TERF1,PURA,DDX52 |
| 1.754e-03 | -6.35 | REACTOME_FACTORS_INVOLVED_IN_MEGAKARYOCYTE_DEVELOPMENT_AND_PLATELET_PRODUCTION | MSigDB lists | REACTOME_FACTORS_INVOLVED_IN_MEGAKARYOCYTE_DEVELOPMENT_AND_PLATELET_PRODUCTION | 126 | 32 | 17377 | 2626 |
KIF3B,RAC1,VPS45,KLC1,KIF23,RACGAP1,IRF3,KIF2C,PRKACA,KIFC1,CDK5,KIF5B,CDC42,CAPZA1,KIF22,KIFAP3,CABLES2,KIF15,PRKAR1B,RCOR1,CAPZA2,KIF11,MFN2,AKAP1,KIF2A,RAD51C,KIF18A,MAFK,H3F3A,CDK2,CABLES1,HDAC2 |
| 1.754e-03 | -6.35 | DARS (aspartyl-tRNA synthetase) | protein interactions | 1615 | 90 | 26 | 17029 | 2761 |
USP7,KARS,LARS,STAU1,CYLD,FOXM1,CUL3,RPL15,CUL1,BRCA1,MCM2,ATP6V1B2,VDAC1,RPL27A,SDHA,RMC1,RPL36,RPL23A,RPA2,PFDN5,EPRS,IARS,QARS,CRY2,ZNF598,EEF1D |
| 1.754e-03 | -6.35 | SEPT2 (septin 2) | protein interactions | 4735 | 90 | 26 | 17029 | 2761 |
SART1,COPA,SEPT9,COPE,MRPL12,SEPT8,CSNK2A1,PRPF3,BRCA1,SRSF5,SEPT7,DAZAP2,ANLN,STMN1,ISG15,PLEKHF2,SEPT1,SURF4,CCDC6,PIK3R2,ZNF326,TRA2B,SEPT11,SRSF3,HNRNPM,SRSF10 |
| 1.754e-03 | -6.35 | STRAP (serine/threonine kinase receptor associated protein) | protein interactions | 11171 | 90 | 26 | 17029 | 2761 |
PDPK1,FYTTD1,SNRPB,RNPS1,DDX20,BRCA1,CAPZA2,SNRPD3,WWP2,GEMIN5,CSDE1,SMAD2,RPS27A,HUWE1,AXIN1,CTPS1,CAPZA1,GEMIN6,ACADM,CHEK2,GEMIN4,SMURF1,RPRD1B,STRAP,SZRD1,GEMIN7 |
| 1.754e-03 | -6.35 | TMEM63B (transmembrane protein 63B) | protein interactions | 55362 | 90 | 26 | 17029 | 2761 |
SCAMP3,PHB2,ERLIN1,RAF1,TMEM109,TAP1,VDAC2,FLOT1,ATP5F1B,VKORC1,ATP6V1B2,DDX39A,MAPK14,MAGED2,RPN1,GOLGA4,ATP1A1,SLC38A5,ATP2A2,SARAF,ATP6V0A2,CHMP4B,ATP5F1A,APOL2,ATP6V0D1,ATP6V1G1 |
| 1.754e-03 | -6.35 | NBN (nibrin) | protein interactions | 4683 | 90 | 26 | 17029 | 2761 |
PHRF1,PRKDC,SUMO2,TLK1,BRCA1,DCLRE1C,BLM,RPA1,XRCC5,TERF2IP,RPA2,MDM2,HSPA4,RAD18,CD3EAP,MSH2,H2AFX,CHEK2,ATF2,MCPH1,XRCC4,TERF1,EYA2,MSH6,TERF2,CDC5L |
| 1.757e-03 | -6.34 | RPS7P4 (ribosomal protein S7 pseudogene 4) | protein interactions | 149224 | 7 | 5 | 17029 | 2761 |
CUL1,RPA2,RPA1,CAND1,CUL3 |
| 1.757e-03 | -6.34 | OARD1 (O-acyl-ADP-ribose deacylase 1) | protein interactions | 221443 | 7 | 5 | 17029 | 2761 |
MYH9,TIMM13,YWHAH,APP,EEF1D |
| 1.757e-03 | -6.34 | UL35 (tegument protein UL35) | protein interactions | 3077429 | 7 | 5 | 17029 | 2761 |
USP7,DDA1,IPO4,DDB1,OGT |
| 1.757e-03 | -6.34 | TMPRSS5 (transmembrane serine protease 5) | protein interactions | 80975 | 7 | 5 | 17029 | 2761 |
CDC42SE2,ARF5,TOR3A,BDH1,N4BP2L2 |
| 1.757e-03 | -6.34 | PLCE1 (phospholipase C epsilon 1) | protein interactions | 51196 | 7 | 5 | 17029 | 2761 |
FUS,NRAS,SIAH1,HRAS,SIAH2 |
| 1.757e-03 | -6.34 | FIG4 (FIG4 phosphoinositide 5-phosphatase) | protein interactions | 9896 | 7 | 5 | 17029 | 2761 |
SNX27,CMAS,PIKFYVE,TWISTNB,MYO18A |
| 1.757e-03 | -6.34 | STAB1 (stabilin 1) | protein interactions | 23166 | 7 | 5 | 17029 | 2761 |
GGA2,GGA1,CHID1,PIK3R2,CDC5L |
| 1.757e-03 | -6.34 | REEP5 (receptor accessory protein 5) | protein interactions | 7905 | 72 | 22 | 17029 | 2761 |
PSRC1,ACSL3,SMARCA4,GALNT7,VKORC1,RGS2,RAB5B,EBP,AKAP1,MFN2,ZMYM3,GALNT2,DNAJC8,KDM2A,RNFT1,FAM3C,ZDHHC7,ATP6V0A2,BRD7,SCAMP4,ATP6V0E1,NUDT3 |
| 1.760e-03 | -6.34 | TGFBR1 (transforming growth factor beta receptor 1) | protein interactions | 7046 | 196 | 48 | 17029 | 2761 |
RHOG,WDR13,UBXN1,XIAP,UBE2Z,EIF2AK4,CSNK1A1,PSEN1,MAPK14,PPP1R16B,GNB2,RTKN,FANCL,FKBP1A,NEK6,CDC42,PIK3R2,PPP6C,SOCS6,AP2B1,STRAP,RNF5,PREB,RPAP3,TGFB1,TTPAL,RHOA,DCAF6,AURKB,STYXL1,TOLLIP,APPL1,ARHGAP15,SMAD2,HSPA4,FNTA,RPS27A,TAB2,PML,SAMD8,PRPF4,CLU,SMAD1,USP11,SMURF1,SAT2,SMAD4,RHEBL1 |
| 1.765e-03 | -6.34 | tubulin binding | molecular function | GO:0015631 | 347 | 74 | 17224 | 2647 |
ZNF207,MYH9,KIF2C,LYN,MAP1LC3B,STMN1,PRNP,DST,KIFC1,CDK5,ABRAXAS2,DPYSL2,KIF14,DNM2,KIF22,MAST2,OGG1,DCTN1,CHP1,PLK1,MAPRE2,PSRC1,TUBGCP5,KIF15,EZR,NUSAP1,BRCA1,EML4,KRIT1,KIF2A,KIF18B,MAP4,MYO18A,GAS2,PPP5C,REEP4,RAD51D,KIF3B,HSPH1,MAPRE1,MZT1,RAE1,KIF23,RACGAP1,MYO9B,RAB11A,TUBGCP2,NEIL2,SPAG5,JAKMIP1,KIF5B,STARD9,SMC3,CENPJ,KIF13B,PRC1,ARHGEF2,MYO5A,CAMSAP1,MACF1,KIF11,PHF6,MYO1F,HAUS8,KIF18A,FNTA,GOLGA2,BIRC5,TTLL4,FAM83D,LRPPRC,CCDC69,MYO9A,NDE1 |
| 1.767e-03 | -6.34 | CCT3 (chaperonin containing TCP1 subunit 3) | protein interactions | 7203 | 262 | 61 | 17029 | 2761 |
CYLD,COPA,POC1A,SUZ12,RAF1,ACTR3,VAV2,WDTC1,CDK13,ARF1,GNB2,CDC73,CDK5,DTL,RFWD3,RPN1,PSMA6,UTP18,HUWE1,AHSA1,ZNF746,SUCLG2,RBM3,ATF2,SEH1L,PDCL3,MLST8,NIPSNAP1,LDHB,CDC5L,MOB4,JMJD4,CCT2,VHL,DCAF8,LDHA,GBA,CUL3,WDR82,BRCA1,DNAJA1,MCM2,CDK11A,CCT8,TRIM28,ISG15,PPP2CA,KPNA4,CAMKMT,MAPK6,DCAF11,PRPF4,XRCC3,FUS,WDR76,CDK2,CD81,IGBP1,DCAF5,PPP2R2D,SSSCA1 |
| 1.769e-03 | -6.34 | regulation of cyclin-dependent protein serine/threonine kinase activity | biological process | GO:0000079 | 86 | 24 | 17256 | 2622 |
BCCIP,PLK1,CCNC,ADAM17,PSRC1,TNFAIP3,GTPBP4,CDC6,PKMYT1,CCNL2,CCNB1,BLM,MEN1,CCNK,CDKN2C,TFAP4,HHEX,PTEN,FBXO7,CDKN1B,PKD2,NR2F2,CDKN2A,CDC37 |
| 1.770e-03 | -6.34 | Renal cell carcinoma | KEGG pathways | ko05211 | 64 | 20 | 7161 | 1149 |
TGFB1,NRAS,RBX1,VHL,RAF1,AKT2,SLC2A1,RAC1,KRAS,ETS1,MAP2K2,MAPK3,CRKL,RAP1A,CDC42,PIK3R2,PTPN11,MAPK1,HRAS,EGLN1 |
| 1.770e-03 | -6.34 | Renal cell carcinoma | KEGG pathways | hsa05211 | 64 | 20 | 7161 | 1149 |
TGFB1,NRAS,RBX1,VHL,RAF1,AKT2,SLC2A1,RAC1,KRAS,ETS1,MAP2K2,MAPK3,CRKL,RAP1A,CDC42,PIK3R2,PTPN11,MAPK1,HRAS,EGLN1 |
| 1.772e-03 | -6.34 | regulation of double-strand break repair | biological process | GO:2000779 | 58 | 18 | 17256 | 2622 |
TRIP12,FOXM1,RAD51AP1,HELB,MRNIP,TERF2IP,RPA2,CYREN,KLHL15,PARPBP,PML,TIMELESS,SLF1,OGG1,SLF2,SPIDR,RNF169,POLQ |
| 1.775e-03 | -6.33 | GCM_NPM1 | MSigDB lists | GCM_NPM1 | 111 | 29 | 17377 | 2626 |
RPL29,RPS2,RPL35,H2AFZ,NASP,POLR2G,SUMO2,NACA,RPL6,PSMA1,RPS24,SNRPD3,FXR1,RPL27A,TRIM28,RPS9,RPSA,RPL11,NAP1L1,HINT1,RPL32,RPS27A,RPL17,DUT,QARS,RPS14,UQCRH,RPL19,HNRNPM |
| 1.775e-03 | -6.33 | NIN (ninein) | protein interactions | 51199 | 118 | 32 | 17029 | 2761 |
FGFR1OP,LUZP1,DCTN2,HMGN3,HAUS4,CCNB1,UBE2I,CSNK1A1,PRKACA,KIF14,TXLNA,GPATCH1,AHCY,CEP63,TP53BP2,ABI1,POC5,DCTN1,SAMD4B,PLK1,CCDC138,ANLN,ERC1,ECH1,DOT1L,HAUS8,UPF1,EIF4ENIF1,PCM1,YWHAH,CCNB2,DYNC1LI2 |
| 1.776e-03 | -6.33 | KINESIN_MOTOR_2 | prosite domains | PS50067 | 44 | 14 | 12060 | 1670 |
KIF5B,KIF2A,KIFC1,STARD9,KIF3B,KIF18A,KIF18B,KIF14,KIF13B,KIF15,KIF23,KIF22,KIF2C,KIF11 |
| 1.778e-03 | -6.33 | RBM11 (RNA binding motif protein 11) | protein interactions | 54033 | 16 | 8 | 17029 | 2761 |
USP7,ZCCHC8,DAZAP2,PCBP1,LYN,TTC33,APP,SF3B2 |
| 1.778e-03 | -6.33 | Tubgcp5 (tubulin, gamma complex associated protein 5) | protein interactions | 233276 | 16 | 8 | 17029 | 2761 |
MZT2A,MZT1,TRIP12,TAP1,SLC25A19,TUBGCP2,TMEM131,SSR1 |
| 1.778e-03 | -6.33 | PRUNE2 (prune homolog 2) | protein interactions | 158471 | 16 | 8 | 17029 | 2761 |
EIF3K,RPS24,EIF2A,EWSR1,LYN,RPS26,RPSA,DYNC1LI2 |
| 1.778e-03 | -6.33 | PBDC1 (polysaccharide biosynthesis domain containing 1) | protein interactions | 51260 | 16 | 8 | 17029 | 2761 |
SEC24C,BABAM1,STRN4,CUL3,ATP6V1B2,TTLL12,LUC7L2,SSRP1 |
| 1.778e-03 | -6.33 | FBXO44 (F-box protein 44) | protein interactions | 93611 | 16 | 8 | 17029 | 2761 |
RBX1,CUL1,CDK13,BRCA1,RGS2,COPS6,ECPAS,DDB1 |
| 1.778e-03 | -6.33 | FEZ1 (fasciculation and elongation protein zeta 1) | protein interactions | 9638 | 81 | 24 | 17029 | 2761 |
PLK1,IMMT,FEZ2,TOMM20,SCOC,ASPM,DRAP1,ANK3,MRS2,CIB1,DNAAF5,UBE4B,PDCD7,BORA,GTF2F1,TEDC2,SMC3,NEK1,NDUFB9,CREB1,SAP30L,MYO5A,GEMIN7,SMARCD1 |
| 1.778e-03 | -6.33 | RALBP1 (ralA binding protein 1) | protein interactions | 10928 | 81 | 24 | 17029 | 2761 |
REPS2,GOPC,RAC1,EPN1,GTF3A,CCNB1,RUFY1,REPS1,PICALM,SAPCD2,POLR2A,FADD,KIFC1,ANKRD26,GOLGA4,RALB,CCDC6,GPS2,PPP4R1,GTSE1,SMARCE1,AP2S1,GCC1,NUMB |
| 1.778e-03 | -6.33 | P3H1 (prolyl 3-hydroxylase 1) | protein interactions | 64175 | 81 | 24 | 17029 | 2761 |
PPP3CA,PPP1R12A,KRBA1,VHL,ERO1A,RBM8A,TIGD5,CUL3,RNPS1,AGFG1,SEC16A,WDR48,SH3GLB1,DDX17,MAT2B,MBIP,HSPBP1,PPME1,WDR4,OGT,H2AFX,PDIA6,LRSAM1,SZRD1 |
| 1.785e-03 | -6.33 | HADDAD_B_LYMPHOCYTE_PROGENITOR | MSigDB lists | HADDAD_B_LYMPHOCYTE_PROGENITOR | 264 | 58 | 17377 | 2626 |
WSB2,ZBTB10,FAM208B,PNISR,TCF3,GADD45G,TIA1,ZNF107,SMARCA4,MEF2A,TOP2B,CDK13,AGFG1,PLXNA1,AP1B1,SNN,CDKN2C,IRF4,RB1,PCNA,GSDMB,RIMS3,FJX1,PDS5B,CDKN1B,CITED2,FAM171A1,PCBP2,PTPRK,USP34,POU2AF1,SNX2,RB1CC1,PSPC1,BTG2,GNG7,ZMYM5,MAP4K4,EZR,RRM2,VDAC1,CYFIP2,SPPL2B,RHOB,PLEKHF2,ANKRD10,TTC13,DCK,STK38,SIAH2,QRSL1,PKD2,HMGB2,SMAD1,NGLY1,LONP2,TOB1,N4BP2L2 |
| 1.792e-03 | -6.32 | purine nucleotide biosynthetic process | biological process | GO:0006164 | 151 | 37 | 17256 | 2622 |
GALK1,COX5B,PPCS,SLC35B2,ATP5F1B,ADPGK,ATP5PF,GART,ATIC,ADCY9,PPCDC,ATP6V0A2,SLC26A2,CYC1,ADCY7,AMPD2,TGFB1,GUK1,LDHA,ATP6V0A1,ADSL,OGDH,ATP5MF,PKM,STOML2,ADSS,ATP5MC3,GUCY1B1,PRPS2,DHTKD1,ACAT1,IMPDH1,ATP5F1A,GPI,NIPSNAP2,PGAM1,PFKP |
| 1.795e-03 | -6.32 | AFG3L2 (AFG3 like matrix AAA peptidase subunit 2) | protein interactions | 10939 | 59 | 19 | 17029 | 2761 |
CYLD,NDUFS1,TIMMDC1,PHB2,ELL2,SUZ12,CHCHD2,NDUFA4,BECN1,APP,PHC2,USF1,RPN1,ATP1A1,NDUFA11,NDUFS8,ATP5F1A,CYC1,CLN3 |
| 1.795e-03 | -6.32 | SBDS (SBDS, ribosome maturation factor) | protein interactions | 51119 | 59 | 19 | 17029 | 2761 |
SARNP,CUL3,GORASP2,UBE4B,NDUFA7,EFL1,TOMM40,SPR,LMNA,DDX17,TERF2IP,NDUFA2,PRPS2,RBMS1,DDX5,CLN3,TERF1,POT1,CAMK2G |
| 1.795e-03 | -6.32 | PSMB8 (proteasome subunit beta 8) | protein interactions | 5696 | 59 | 19 | 17029 | 2761 |
USP7,CCT2,PSMA8,TAP1,PSMB7,PSMA1,POMP,PSMB9,PSMB3,PSMC4,PSMD2,PSMA6,PSMD1,PSMD3,PSMD8,UCHL5,TAP2,PSMC1,HNRNPM |
| 1.795e-03 | -6.32 | RBBP8 (RB binding protein 8, endonuclease) | protein interactions | 5932 | 59 | 19 | 17029 | 2761 |
PLK1,SCOC,WDYHV1,PRKDC,RAF1,CUL3,BRCA1,BRIX1,RB1,MDM2,PCNA,TMEM54,PALB2,RBL1,SIAH1,PIN1,KLHL15,SIAH2,CLU |
| 1.798e-03 | -6.32 | GSE16385_IFNG_TNF_VS_UNSTIM_MACROPHAGE_ROSIGLITAZONE_TREATED_UP | MSigDB lists | GSE16385_IFNG_TNF_VS_UNSTIM_MACROPHAGE_ROSIGLITAZONE_TREATED_UP | 157 | 38 | 17377 | 2626 |
ZNF296,ZNF496,SMAP1,MAX,TXN,PARP12,DEPDC1,DCAF15,CDT1,CENPF,VTI1A,UBE2Z,PCBP1,STAM,RPA2,FANCL,RAB8A,TNS3,MDM2,MED10,IL6ST,TXLNA,INTS12,CISD2,NUDC,ADCY7,CDC6,MAP7D1,RANGAP1,BUD13,PATL1,RAB2B,MFAP1,TBPL1,USP11,NDE1,PARP10,SSSCA1 |
| 1.800e-03 | -6.32 | PDIA6 (protein disulfide isomerase family A member 6) | protein interactions | 10130 | 104 | 29 | 17029 | 2761 |
TXNL1,UNK,PPP3CA,CYLD,EWSR1,CUL3,CUL1,CSNK2A1,NOTCH2,ADRB2,VKORC1,MCM2,GLRX3,MACF1,SDHA,CDC73,PARK7,CLNS1A,CAND1,MAT2B,RPN1,PFDN5,TPD52L2,HUWE1,H2AFX,CDK2,CD81,SMURF1,IGBP1 |
| 1.800e-03 | -6.32 | ZBTB1 (zinc finger and BTB domain containing 1) | protein interactions | 22890 | 104 | 29 | 17029 | 2761 |
ZNF76,LZTR1,EWSR1,H2AFZ,GPBP1L1,MTA2,TRIR,TWNK,SUMO2,RPL8,ARHGDIB,BCLAF1,SNRPD3,UBE2I,RPL27A,TRIM28,RPS9,RPSA,SRSF1,RPL11,PSMD2,PCNA,HNRNPR,RPS14,KIF14,STK38,ACTB,TUBB,SPTAN1 |
| 1.800e-03 | -6.32 | DPPA4 (developmental pluripotency associated 4) | protein interactions | 55211 | 104 | 29 | 17029 | 2761 |
TXN,ADD1,SUZ12,PDAP1,TOR3A,NACA,USP42,TIGD5,TIA1,LETMD1,EDF1,PBRM1,PCGF1,MCM2,KIF11,TUBGCP2,PLEKHF2,RBM17,UPF1,NSF,HUWE1,L3MBTL3,QARS,MAPK6,NAA50,CLU,SASS6,DDB1,USP34 |
| 1.809e-03 | -6.31 | GSE21063_CTRL_VS_ANTI_IGM_STIM_BCELL_16H_UP | MSigDB lists | GSE21063_CTRL_VS_ANTI_IGM_STIM_BCELL_16H_UP | 178 | 42 | 17377 | 2626 |
ZCCHC8,CDT1,KIF23,RACGAP1,CNTROB,ASXL2,RCOR3,TMEM161B,HDDC2,TFRC,SPAG5,FBXO5,VAV1,CLIC4,CCNA2,STRBP,NVL,PRC1,AKR1B1,TIMELESS,INTS12,CLDND1,RNASEH2A,RNF26,DNMT1,HP1BP3,ASPM,TUBGCP5,ABHD11,BORA,TRIM28,SNRPA,NAP1L1,MTHFD2,BIRC5,STT3A,NRM,CEP55,IDH3B,RBBP4,CCNB2,UBE2C |
| 1.809e-03 | -6.31 | GSE5542_UNTREATED_VS_IFNA_AND_IFNG_TREATED_EPITHELIAL_CELLS_24H_UP | MSigDB lists | GSE5542_UNTREATED_VS_IFNA_AND_IFNG_TREATED_EPITHELIAL_CELLS_24H_UP | 178 | 42 | 17377 | 2626 |
RECQL,SART1,IMMT,NSMCE4A,GXYLT1,TM9SF4,PHB2,B4GALT5,TSC22D3,DBF4,MRPS26,TRAK1,RGS1,FBXL6,SHC1,NT5DC1,WDR44,RABGAP1L,EXOSC1,AP2B1,TAP2,GLE1,MRPL48,MYO5A,ELOF1,VOPP1,TRAFD1,CDC123,KAT7,PSMB7,WDR81,GLOD4,NSA2,PDCD6,PFDN4,QARS,MRPL27,HAGHL,APPL2,RBPJ,ZMIZ1,USF2 |
| 1.809e-03 | -6.31 | GSE20727_CTRL_VS_H2O2_TREATED_DC_UP | MSigDB lists | GSE20727_CTRL_VS_H2O2_TREATED_DC_UP | 178 | 42 | 17377 | 2626 |
INTS2,CCDC93,MAX,GGA1,MANBA,B4GALT5,TSC22D3,MEF2A,RUFY1,GIT2,HEATR5B,KIAA1147,WRNIP1,WWP2,PCYOX1L,USF1,HOMER1,KLF16,RCSD1,ZFYVE27,CNPY3,TERF2,PDLIM2,LARS,DEAF1,TRAPPC9,MAPRE2,VHL,KDM1B,PLEKHF2,EPB41,TFEB,PI4K2A,PFDN5,SERTAD2,BBX,DTX4,RBMS1,ACTB,CD81,ZC3HAV1,IFI16 |
| 1.809e-03 | -6.31 | GSE6875_WT_VS_FOXP3_KO_TREG_UP | MSigDB lists | GSE6875_WT_VS_FOXP3_KO_TREG_UP | 178 | 42 | 17377 | 2626 |
NSMCE4A,ANKRD13D,TMUB1,NF1,DAP,PDAP1,TCF3,GADD45G,CHIC2,REEP5,ATP6V0B,SIAH1,NT5DC1,RAB35,INTS1,MBD2,ZBTB22,CNN2,AQR,PLCL2,SAP30L,SMC4,SPTAN1,SAP30,VOPP1,RHOA,NEK7,AKT2,ANKRD33B,KIAA0930,KDM3A,ARF4,TWISTNB,PTPRF,AMZ2,MRPL2,BRWD1,SNAP29,RGL1,EHD4,MYO9A,N4BP2L2 |
| 1.809e-03 | -6.31 | GSE13484_12H_VS_3H_YF17D_VACCINE_STIM_PBMC_UP | MSigDB lists | GSE13484_12H_VS_3H_YF17D_VACCINE_STIM_PBMC_UP | 178 | 42 | 17377 | 2626 |
BCCIP,SMAP1,AGRN,GNPDA1,DYNLL1,ADO,AGPAT1,PLAGL2,BTN3A1,DCUN1D4,METTL3,KTN1,SNRNP25,THADA,AKR1B1,SUCLG2,MAVS,RNASEH2A,DNMT1,ABI1,HTRA2,FDFT1,VPS13B,CDKN2AIP,SEPT9,PGS1,POLR2D,PIP4K2C,CBFA2T2,BORA,POLG2,PRDX1,MYO1F,CHCHD3,ACYP1,LSM6,OAZ2,MEGF9,ATP6V0C,SNRNP70,MAPK1,COIL |
| 1.809e-03 | -6.31 | GSE17721_0.5H_VS_4H_GARDIQUIMOD_BMDC_UP | MSigDB lists | GSE17721_0.5H_VS_4H_GARDIQUIMOD_BMDC_UP | 178 | 42 | 17377 | 2626 |
RHOG,C9orf78,KIAA0100,PRKCSH,UBXN1,PRKACA,C14orf119,RPN1,FBXL6,IARS,TBC1D22A,SSBP3,FIZ1,AP1M1,H2AFY,RPL19,SPTSSA,LPCAT1,MTX2,TIMM50,TIMP2,POLR2G,SNX2,ERLIN1,DRAP1,LDHA,POLR3GL,PSMG1,DNAJC9,UBE2V1,MTX1,GALK2,SLC50A1,CLNS1A,DHX57,TFEB,UTP20,ACYP1,MFAP1,PREPL,EHD4,ZMAT3 |
| 1.809e-03 | -6.31 | GSE29618_PRE_VS_DAY7_POST_TIV_FLU_VACCINE_MONOCYTE_DN | MSigDB lists | GSE29618_PRE_VS_DAY7_POST_TIV_FLU_VACCINE_MONOCYTE_DN | 178 | 42 | 17377 | 2626 |
IER2,PPIB,TRIP10,C1orf112,STRN4,DLGAP4,KIF23,ARFIP2,SLC4A2,NENF,CHKB,MAP1LC3B,SYNRG,POLR3K,DDRGK1,WWP2,KRR1,IARS,CRAT,MEGF8,ARF5,CEP63,CLTB,SCYL3,SAP30L,ZNF189,DDX24,ZNF84,SUGP2,WBP2,USP10,BMS1,MEN1,NDUFB1,PRMT2,ARF4,SRSF1,PSMD3,GADD45B,PPM1G,GPI,S100PBP |
| 1.809e-03 | -6.31 | GSE13738_TCR_VS_BYSTANDER_ACTIVATED_CD4_TCELL_DN | MSigDB lists | GSE13738_TCR_VS_BYSTANDER_ACTIVATED_CD4_TCELL_DN | 178 | 42 | 17377 | 2626 |
CCDC93,CYLD,TXN,SH2D3A,PPP1R12A,IVNS1ABP,ANK3,PCSK7,ZNF267,DNAJB9,CAPN2,ATP6V0B,AHSA1,BCL2,TALDO1,MYBL1,TMBIM1,ABCC5,PDLIM2,CYTH1,FTL,ATP13A1,BIRC3,GUK1,KIAA0040,LYRM1,CPOX,ARHGEF12,ABHD11,ICAM2,EML4,OPTN,FAS,RAB18,TRIM26,MAGT1,TAB2,ITGB1,PREPL,PDLIM5,NIPA1,N4BP2L2 |
| 1.809e-03 | -6.31 | GSE25123_ROSIGLITAZONE_VS_IL4_AND_ROSIGLITAZONE_STIM_PPARG_KO_MACROPHAGE_DAY10_DN | MSigDB lists | GSE25123_ROSIGLITAZONE_VS_IL4_AND_ROSIGLITAZONE_STIM_PPARG_KO_MACROPHAGE_DAY10_DN | 178 | 42 | 17377 | 2626 |
HIVEP3,TCF12,UBL3,GALK1,PTMS,PPCS,HLA-E,WDR13,SIKE1,MYO9B,RLF,RCOR3,FOXO3,ANKIB1,GIT2,ATP6V0B,RAP1A,TNFAIP8,CNN2,FAM76B,SLC35C2,LDLRAD3,GM2A,TRIM14,TNFAIP3,SIGMAR1,TUBGCP5,MAP7D1,MAP4K3,RAB3IP,LRRC1,STX16,MARK2,BSDC1,NECAP2,SLCO4A1,SCAP,HPS5,KBTBD7,BCL7C,ARAP1,ALS2 |
| 1.809e-03 | -6.31 | GSE40666_NAIVE_VS_EFFECTOR_CD8_TCELL_WITH_IFNA_STIM_90MIN_DN | MSigDB lists | GSE40666_NAIVE_VS_EFFECTOR_CD8_TCELL_WITH_IFNA_STIM_90MIN_DN | 178 | 42 | 17377 | 2626 |
RMND5A,ZNF207,HNRNPAB,KRBA1,ARID2,MUM1,FLOT1,BCL2L1,CSNK1A1,PPP1R16B,BZW2,HMG20A,MFSD10,SSR1,HOMER1,GART,CENPJ,MCM5,JAZF1,FIZ1,MTX2,N4BP2,PPA1,NSUN4,MSH6,LDHB,TGFB1,HEMK1,CSRP1,ILF3,E2F3,SREK1,WBP1,ARID1A,PRKRA,DHX57,TWSG1,PSMD3,CD81,CHPT1,RTN3,S100PBP |
| 1.811e-03 | -6.31 | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides | molecular function | GO:0016811 | 90 | 25 | 17224 | 2647 |
NADSYN1,WDYHV1,MTA2,MIER1,RCOR1,ASAH1,MIER2,NIT2,SIRT2,AMDHD2,PM20D2,MBD3,CAT,BRMS1,CHD3,HDAC7,MTA1,QRSL1,RBBP4,NGLY1,SAP30L,ARID4A,HDAC2,PDF,SAP30 |
| 1.815e-03 | -6.31 | RAMPON_ENRICHED_LEARNING_ENVIRONMENT_EARLY_UP | MSigDB lists | RAMPON_ENRICHED_LEARNING_ENVIRONMENT_EARLY_UP | 17 | 8 | 17377 | 2626 |
PHC2,CALM2,RHOA,MFAP1,TLK1,MAP4K3,DNMT1,HNRNPM |
| 1.815e-03 | -6.31 | GO_DNA_DIRECTED_RNA_POLYMERASE_II_CORE_COMPLEX | MSigDB lists | GO_DNA_DIRECTED_RNA_POLYMERASE_II_CORE_COMPLEX | 17 | 8 | 17377 | 2626 |
POLR2I,POLR2G,POLR2L,POLR2J,POLR2K,ZNF768,POLR2A,POLR2D |
| 1.815e-03 | -6.31 | GO_CELL_SEPARATION_AFTER_CYTOKINESIS | MSigDB lists | GO_CELL_SEPARATION_AFTER_CYTOKINESIS | 17 | 8 | 17377 | 2626 |
CHMP2A,CHMP4B,PDCD6IP,VPS4A,CHMP4A,CHMP2B,CHMP7,CEP55 |
| 1.815e-03 | -6.31 | REACTOME_G1_S_SPECIFIC_TRANSCRIPTION | MSigDB lists | REACTOME_G1_S_SPECIFIC_TRANSCRIPTION | 17 | 8 | 17377 | 2626 |
PCNA,TFDP1,CDT1,E2F1,RRM2,CDC6,ORC1,FBXO5 |
| 1.815e-03 | -6.31 | GO_CHD_TYPE_COMPLEX | MSigDB lists | GO_CHD_TYPE_COMPLEX | 17 | 8 | 17377 | 2626 |
CHD3,MTA2,APPL2,CSNK2A1,RBBP4,MBD3,APPL1,HDAC2 |
| 1.815e-03 | -6.31 | GO_REGULATION_OF_DNA_METHYLATION | MSigDB lists | GO_REGULATION_OF_DNA_METHYLATION | 17 | 8 | 17377 | 2626 |
MBD1,DNMT3A,MPHOSPH8,MECP2,BRCA1,KDM1B,MBD3,DNMT1 |
| 1.815e-03 | -6.31 | REACTOME_DESTABILIZATION_OF_MRNA_BY_KSRP | MSigDB lists | REACTOME_DESTABILIZATION_OF_MRNA_BY_KSRP | 17 | 8 | 17377 | 2626 |
EXOSC6,EXOSC7,EXOSC1,KHSRP,EXOSC9,YWHAZ,PARN,MAPK14 |
| 1.815e-03 | -6.31 | PID_SMAD2_3PATHWAY | MSigDB lists | PID_SMAD2_3PATHWAY | 17 | 8 | 17377 | 2626 |
KPNA2,NUP153,SMAD2,UBE2I,MAPK1,SMAD4,CTDSP2,MAPK3 |
| 1.815e-03 | -6.31 | REACTOME_SHC_RELATED_EVENTS | MSigDB lists | REACTOME_SHC_RELATED_EVENTS | 17 | 8 | 17377 | 2626 |
KRAS,NRAS,SHC1,MAPK1,MAP2K2,HRAS,RAF1,MAPK3 |
| 1.815e-03 | -6.31 | REACTOME_ARMS_MEDIATED_ACTIVATION | MSigDB lists | REACTOME_ARMS_MEDIATED_ACTIVATION | 17 | 8 | 17377 | 2626 |
KRAS,RAP1A,NRAS,MAPK1,MAP2K2,HRAS,RAF1,MAPK3 |
| 1.815e-03 | -6.31 | BIOCARTA_ERK5_PATHWAY | MSigDB lists | BIOCARTA_ERK5_PATHWAY | 17 | 8 | 17377 | 2626 |
MEF2A,MEF2D,CREB1,SHC1,MAPK1,RPS6KA1,HRAS,MAPK3 |
| 1.815e-03 | -6.31 | GO_NEGATIVE_REGULATION_OF_CELL_CYCLE_ARREST | MSigDB lists | GO_NEGATIVE_REGULATION_OF_CELL_CYCLE_ARREST | 17 | 8 | 17377 | 2626 |
MIF,TFAP4,CCNK,MDM2,HMGN5,CAST,ZNF268,CHEK2 |
| 1.823e-03 | -6.31 | GO_RETROGRADE_TRANSPORT_ENDOSOME_TO_GOLGI | MSigDB lists | GO_RETROGRADE_TRANSPORT_ENDOSOME_TO_GOLGI | 63 | 19 | 17377 | 2626 |
SNX8,GCC2,RHOBTB3,SNX2,RAB7A,VTI1A,RAB6A,STX16,GOSR1,ERC1,TBC1D17,SURF4,VPS26B,TBC1D14,AP1S1,PIKFYVE,LMAN1,VPS29,DCTN1 |
| 1.823e-03 | -6.31 | CCAGGTT,MIR-490 | MSigDB lists | CCAGGTT,MIR-490 | 63 | 19 | 17377 | 2626 |
C16orf72,MBLAC2,OXR1,FAM76A,PBRM1,LUC7L,PCBP1,GNB2,PAPOLA,DDX17,SUGP1,AHCTF1,PPME1,TRMU,OGT,SMURF1,FBXL19,PCBP2,SMARCD1 |
| 1.824e-03 | -6.31 | post-Golgi vesicle-mediated transport | biological process | GO:0006892 | 91 | 25 | 17256 | 2622 |
CCDC93,RAB14,GCC2,CORO7,GOLPH3L,SYS1,SCAMP3,GOPC,ANK3,VTI1A,RABIF,CHIC2,TGOLN2,ARF1,MACF1,OPTN,GOLGA4,KLHL20,GOLGA7,NSF,SNAP23,DNM2,EXOC4,RP2,MYO5A |
| 1.824e-03 | -6.31 | mitochondrial transmembrane transport | biological process | GO:1990542 | 91 | 25 | 17256 | 2622 |
COX5B,TOMM20,MRS2,SLC25A12,TIMM21,ATP5F1B,ATP5MF,TOMM40,ATP5PF,MPC1,SLC25A37,STOML2,SLC25A36,TIMM13,MID1IP1,ATP5MC3,TIMM23,TIMM29,TIMM17A,MICU2,CYC1,ATP5F1A,SLC25A33,SLC25A1,TIMM50 |
| 1.831e-03 | -6.30 | GSE17580_UNINFECTED_VS_S_MANSONI_INF_TEFF_UP | MSigDB lists | GSE17580_UNINFECTED_VS_S_MANSONI_INF_TEFF_UP | 194 | 45 | 17377 | 2626 |
MAPRE1,ADD1,KLHL21,DNAJB2,CAST,CERK,GGA2,LYN,METTL3,RAD23A,PRKD3,MLX,ADD3,MTMR4,SSBP3,DCP1A,MAP3K14,CNPY3,MCMBP,CNNM3,CARM1,ALDH9A1,CDC5L,RBM15B,CSTF1,PPP3CA,RB1CC1,RPL6,RAB3IP,ADRB2,CCDC127,UBTF,PDLIM1,STAT6,AXIN1,MYO18A,APPL2,GALNT10,PPP6R3,PTDSS1,PDCD2L,CBX4,IPO4,NUMB,BYSL |
| 1.831e-03 | -6.30 | CCDC9 (coiled-coil domain containing 9) | protein interactions | 26093 | 23 | 10 | 17029 | 2761 |
WSB2,SARNP,TMEM184B,EIF4A3,RBM8A,NKAPD1,PIP4K2A,TERF1,POT1,LUC7L2 |
| 1.831e-03 | -6.30 | MAGIX (MAGI family member, X-linked) | protein interactions | 79917 | 23 | 10 | 17029 | 2761 |
ERCC1,CDC16,CDC27,ANAPC2,ANAPC7,CDC23,MCMBP,NCAPG,FAF1,ANAPC4 |
| 1.831e-03 | -6.30 | ARL1 (ADP ribosylation factor like GTPase 1) | protein interactions | 400 | 23 | 10 | 17029 | 2761 |
GCC2,STAU1,GOLGA4,PTPN18,SCOC,CUL3,ARFIP2,DUSP22,GCC1,COPG2 |
| 1.831e-03 | -6.30 | CWC15 (CWC15 spliceosome associated protein homolog) | protein interactions | 51503 | 23 | 10 | 17029 | 2761 |
RBM17,SGCE,EWSR1,CTNNBL1,EIF4A3,SF3A2,APP,CDC5L,PRPF19,PRNP |
| 1.831e-03 | -6.30 | CIR1 (corepressor interacting with RBPJ, 1) | protein interactions | 9541 | 23 | 10 | 17029 | 2761 |
NCOR2,NEK6,CDCA3,RBPJ,TCEA1,HDAC2,BTBD1,FANCI,SRSF1,SAP30 |
| 1.831e-03 | -6.30 | NXT2 (nuclear transport factor 2 like export factor 2) | protein interactions | 55916 | 23 | 10 | 17029 | 2761 |
GOLGA2,SSBP3,PTPN11,PTAR1,KRAS,CEP63,PKM,STAT3,APP,SRPK2 |
| 1.840e-03 | -6.30 | proton-transporting two-sector ATPase complex, proton-transporting domain | cellular component | GO:0033177 | 21 | 9 | 18223 | 2701 |
ATP6V0B,ATP5MC3,ATP6V0A2,ATP6V0A1,ATP6V0C,ATP5MF,ATP5PF,ATP6V0E1,ATP6V0D1 |
| 1.841e-03 | -6.30 | GSE21360_SECONDARY_VS_TERTIARY_MEMORY_CD8_TCELL_DN | MSigDB lists | GSE21360_SECONDARY_VS_TERTIARY_MEMORY_CD8_TCELL_DN | 152 | 37 | 17377 | 2626 |
CLSPN,NOP2,RPS6KA1,CHTF18,CUTA,NKRF,SLC29A1,MXD4,S1PR2,RGS2,MAPK14,TCF19,PIP5K1C,INTS7,MTMR4,MCM5,DAPK1,RPAP1,SLC26A2,RNF26,TPCN1,CFL1,ELOF1,WDR41,ADCY7,TK1,PPP1R21,EMP3,CDC6,NFATC2,DIDO1,ASF1B,EVC2,ITPRIPL1,NEIL3,CD81,RAB3IL1 |
| 1.850e-03 | -6.29 | regulation of DNA binding transcription factor activity | biological process | GO:0051090 | 419 | 86 | 17256 | 2622 |
USP7,CYLD,RWDD1,SMARCA4,TAF6L,UBE2I,MAPK14,COMMD6,PARK7,APP,PRNP,TERF2IP,PSMA6,SP100,GLIS2,SRI,MAVS,ATF2,MTPN,TRIM14,DVL2,CARM1,RLIM,CHP1,TRIM8,RNF25,UBE2V1,LRP5,ERBIN,ERC1,BRMS1,TONSL,RPS27A,TAB2,HIPK2,TICAM1,TRIM32,CLU,TRIM52,ARRB2,TRAF5,MAPK1,LRP8,HDAC2,RHEBL1,DDX58,PHB2,DAP,TCF3,DHX9,CIB1,EIF2AK4,MAD2L2,JMY,FZD6,WWP2,CFLAR,DDRGK1,LRRC14,RB1,PTEN,BUD31,ARHGEF2,TGFB1,PPP3CA,IFRD1,TRAPPC9,TNFAIP3,KRAS,MEN1,PRMT2,MAPK3,HSPA1B,CAT,TRIM26,KEAP1,PRDX3,CEBPG,NLRC5,PKD2,TAF12,PARP10,TAF6,FAF1,CDKN2A,EGLN1 |
| 1.861e-03 | -6.29 | coated vesicle | cellular component | GO:0030135 | 275 | 59 | 18223 | 2701 |
TMED7,RAB14,DNAJC5,COPA,HLA-E,SCYL1,COPE,VTI1A,TGOLN2,TMED3,AP1B1,GGA2,SEC16A,SYNRG,SCYL2,BCAP31,APP,COPG2,TFRC,COPB2,HLA-A,CD59,RAB8A,SNX18,SAR1A,RAB35,SEC24C,AP1M1,DNM2,AP2B1,YIF1B,LMAN1,CLTB,TMED2,DVL2,KDELR1,USO1,GOPC,DENND1B,PACS1,ADRB2,MCFD2,PEF1,PICALM,NECAP2,YIF1A,SEC31A,HLA-B,SCARB2,SEC23IP,PDCD6,GOLGA2,TMED10,SCAP,AP1S1,DVL1,ECPAS,AP2S1,NUMB |
| 1.863e-03 | -6.29 | GO_RRNA_BINDING | MSigDB lists | GO_RRNA_BINDING | 54 | 17 | 17377 | 2626 |
NOL12,PPAN,DDX28,RPLP2,RPL8,CIRBP,MRPL16,RPS9,RPL11,RPL23A,RPL37,RPS14,RPLP1,RPF2,RNASEL,MRPL11,NSUN4 |
| 1.863e-03 | -6.29 | KEGG_NON_SMALL_CELL_LUNG_CANCER | MSigDB lists | KEGG_NON_SMALL_CELL_LUNG_CANCER | 54 | 17 | 17377 | 2626 |
PDPK1,NRAS,AKT2,RAF1,E2F3,KRAS,FOXO3,MAP2K2,MAPK3,RXRB,RB1,PIK3R2,E2F1,MAPK1,E2F2,HRAS,CDKN2A |
| 1.863e-03 | -6.29 | GENTILE_UV_RESPONSE_CLUSTER_D4 | MSigDB lists | GENTILE_UV_RESPONSE_CLUSTER_D4 | 54 | 17 | 17377 | 2626 |
KLF10,GNE,USP10,CCNB1,RAB1A,DDX17,KRIT1,PHC2,PDCD10,UAP1,ATP2A2,SIAH1,ATP13A3,MAPK6,TPST1,KPNA2,HMGB2 |
| 1.863e-03 | -6.29 | GO_KINESIN_COMPLEX | MSigDB lists | GO_KINESIN_COMPLEX | 54 | 17 | 17377 | 2626 |
KIF3B,KIF15,KLC1,KIF23,KIF2C,KIF11,KIF5B,KIF2A,KIFC1,STARD9,KIF18A,KIF18B,KIF13B,KIF14,KIF22,KIFAP3,NDE1 |
| 1.863e-03 | -6.29 | GO_REGULATION_OF_EXTRINSIC_APOPTOTIC_SIGNALING_PATHWAY_VIA_DEATH_DOMAIN_RECEPTORS | MSigDB lists | GO_REGULATION_OF_EXTRINSIC_APOPTOTIC_SIGNALING_PATHWAY_VIA_DEATH_DOMAIN_RECEPTORS | 54 | 17 | 17377 | 2626 |
TNFAIP3,NF1,RAF1,RFFL,BRCA1,PARK7,FADD,CFLAR,FAS,SP100,PTEN,DAPK1,ARHGEF2,FEM1B,HMGB2,FAF1,TMBIM1 |
| 1.865e-03 | -6.28 | GSE37605_C57BL6_VS_NOD_FOXP3_FUSION_GFP_TCONV_DN | MSigDB lists | GSE37605_C57BL6_VS_NOD_FOXP3_FUSION_GFP_TCONV_DN | 173 | 41 | 17377 | 2626 |
SRM,CORO7,RPS6KA1,KIF23,RRAGC,ADCK5,CDC42SE2,EIF1B,PRKD3,NDUFV1,TBC1D22A,PHF14,POLR1B,UBE3C,PIKFYVE,CTDSP2,CFL1,VPS13B,FYTTD1,SNX25,GCC2,PRKDC,CPOX,ILF3,E2F3,PCGF6,DCTD,ARID1A,PICALM,MAPK3,TSC1,HSPA4,CDC16,HINT1,WDR11,TFDP1,IARS2,DDX5,PIEZO1,ABCA1,S100PBP |
| 1.865e-03 | -6.28 | GSE18281_MEDULLARY_THYMOCYTE_VS_WHOLE_MEDULLA_THYMUS_UP | MSigDB lists | GSE18281_MEDULLARY_THYMOCYTE_VS_WHOLE_MEDULLA_THYMUS_UP | 173 | 41 | 17377 | 2626 |
ZBTB10,ASH1L,SKA3,GGA1,ZNF768,RPS6KA1,MAGED1,LAGE3,RPL15,CCDC28A,KIAA1147,FKBP1A,PRC1,FBXL7,CNPY3,GPX4,HEMK1,PBXIP1,NQO2,EMB,TAOK1,TEX10,KIAA1586,MEN1,MAP2K2,ASF1B,NMT2,C19orf54,ZNF862,HGS,AGPAT2,QARS,H2AFX,STK11,SMG9,FAU,CLN3,BRD9,MZT2B,CSNK1D,DEF6 |
| 1.865e-03 | -6.28 | GSE21927_SPLEEN_MONOCYTE_VS_GMCSF_GCSF_BONE_MARROW_DN | MSigDB lists | GSE21927_SPLEEN_MONOCYTE_VS_GMCSF_GCSF_BONE_MARROW_DN | 173 | 41 | 17377 | 2626 |
MIF4GD,TXN,C19orf53,PLXNC1,TRERF1,RPLP2,FAM129A,TOR3A,ANK3,JMY,INPP5A,INTS7,NT5DC1,PIK3R2,NAA50,MDFIC,ZNF770,DDX28,OSBP2,CSRP1,KLF10,NQO2,DENND1B,IL12RB1,MCM2,MTR,FAS,HAUS8,TRIM47,BOLA3,ATAD2,PDLIM1,CSNK1G1,FASTK,FN3KRP,ACAT1,TMEM101,DVL1,FAU,ATP6V0E1,NIPA1 |
| 1.878e-03 | -6.28 | The oncogenic action of Fumarate | SMPDB pathways | SMP02295 | 30 | 12 | 992 | 167 |
SDHB,KDM2A,SUCLG1,IDH3A,MDH2,CS,SUCLG2,OGDH,IDH3B,SDHA,MPC1,EGLN1 |
| 1.878e-03 | -6.28 | The oncogenic action of Succinate | SMPDB pathways | SMP02292 | 30 | 12 | 992 | 167 |
SDHB,KDM2A,SUCLG1,IDH3A,MDH2,CS,SUCLG2,OGDH,IDH3B,SDHA,MPC1,EGLN1 |
| 1.880e-03 | -6.28 | response to UV | biological process | GO:0009411 | 136 | 34 | 17256 | 2622 |
BAK1,ERCC1,HMGN1,POLK,PBK,PRKAA1,CIRBP,MAP4K3,AURKB,UBE4B,EIF2AK4,MEN1,METTL3,RHBDD1,DTL,MAP3K4,CAT,USF1,PCNA,MDM2,RAD18,XPA,MSH2,NOC2L,PML,STK11,BCL2,RUVBL2,TRIM32,YY1,GTF2H2,DDB1,MSH6,PTPRK |
| 1.882e-03 | -6.28 | COPB1 (coatomer protein complex subunit beta 1) | protein interactions | 1315 | 95 | 27 | 17029 | 2761 |
UBQLN4,COPA,SF3B1,COPE,TAP1,WBP2,PMS2,TMEM216,KLC1,BRCA1,ERBIN,ARF1,RGS2,APP,COPG2,HLA-A,COPB2,SF3B2,PSMD2,KPNA4,TMED10,TANK,YWHAZ,LMAN1,CDK2,KDELR1,CDC5L |
| 1.882e-03 | -6.28 | cell separation after cytokinesis | biological process | GO:0000920 | 17 | 8 | 17256 | 2622 |
CHMP2A,CHMP4A,PDCD6IP,CEP55,CHMP4B,VPS4A,CHMP2B,CHMP7 |
| 1.882e-03 | -6.28 | septin ring organization | biological process | GO:0031106 | 17 | 8 | 17256 | 2622 |
SEPT11,TMEM250,SEPT8,SEPT1,SEPT9,SEPT7,ANLN,RTKN |
| 1.883e-03 | -6.28 | ACTB (actin beta) | protein interactions | 60 | 346 | 77 | 17029 | 2761 |
WASF2,CORO7,CYLD,HNRNPAB,IVNS1ABP,DYNLL1,WDYHV1,RAC1,ACTR3,SMARCA4,MYH9,CUL1,BCL2L1,LYN,TWF2,RRN3,PA2G4,MDM2,SHC1,EIF4A3,THAP4,UCHL5,PIK3R2,RAB4A,CORO1A,SMARCE1,CARM1,CFL1,SRPK2,CDC5L,CPNE1,CCT2,VHL,CUL3,EZR,TANC1,CLNS1A,CORO1C,MYO18A,BCL7C,H2AFX,ACTB,FUS,COPS6,SMURF1,ARRB2,POT1,UNK,DHX9,RPL15,CSNK1A1,TUBGCP2,LMNA,RPA2,HOMER1,CLIC4,NUS1,TPST1,CAPZA1,OSTF1,POLR1B,CNN2,SPTAN1,STAU1,TK1,CCT8,SFXN5,POLR2A,RPA1,CAND1,GNA12,PFDN4,RUVBL2,PDLIM5,CDK2,CD81,CDKN2A |
| 1.892e-03 | -6.27 | pancreas-carcinoma-mixed_acinar-ductal_carcinoma | COSMIC cancer mutations | pancreas-carcinoma-mixed_acinar-ductal_carcinoma | 21 | 9 | 17385 | 2587 |
RB1,NRAS,TSC2,PTEN,STK11,KRAS,BRCA1,SND1,SMAD4 |
| 1.892e-03 | -6.27 | mixed_acinar-ductal_carcinoma | COSMIC cancer mutations | mixed_acinar-ductal_carcinoma | 21 | 9 | 17385 | 2587 |
RB1,NRAS,TSC2,PTEN,STK11,KRAS,BRCA1,SND1,SMAD4 |
| 1.892e-03 | -6.27 | pancreas-carcinoma-mixed_acinar-neuroendocrine-ductal_carcinoma | COSMIC cancer mutations | pancreas-carcinoma-mixed_acinar-neuroendocrine-ductal_carcinoma | 21 | 9 | 17385 | 2587 |
RB1,NRAS,TSC2,PTEN,STK11,KRAS,BRCA1,SND1,SMAD4 |
| 1.892e-03 | -6.27 | pancreas-carcinoma-mixed_acinar-neuroendocrine_carcinoma | COSMIC cancer mutations | pancreas-carcinoma-mixed_acinar-neuroendocrine_carcinoma | 21 | 9 | 17385 | 2587 |
RB1,NRAS,TSC2,PTEN,STK11,KRAS,BRCA1,SND1,SMAD4 |
| 1.892e-03 | -6.27 | haemangioma | COSMIC cancer mutations | haemangioma | 21 | 9 | 17385 | 2587 |
GNAS,TSC1,KRAS,EWSR1,NRAS,TSC2,PTEN,HRAS,MSH2 |
| 1.892e-03 | -6.27 | mixed_acinar-neuroendocrine-ductal_carcinoma | COSMIC cancer mutations | mixed_acinar-neuroendocrine-ductal_carcinoma | 21 | 9 | 17385 | 2587 |
RB1,NRAS,TSC2,PTEN,STK11,KRAS,BRCA1,SND1,SMAD4 |
| 1.892e-03 | -6.27 | mixed_acinar-neuroendocrine_carcinoma | COSMIC cancer mutations | mixed_acinar-neuroendocrine_carcinoma | 21 | 9 | 17385 | 2587 |
RB1,NRAS,TSC2,PTEN,STK11,KRAS,BRCA1,SND1,SMAD4 |
| 1.894e-03 | -6.27 | USP4 (ubiquitin specific peptidase 4) | protein interactions | 7375 | 109 | 30 | 17029 | 2761 |
DDX58,TK1,RNPS1,ENSA,BRAP,LSM8,ADSL,PTP4A3,PRPF3,USP21,EDC3,RB1,PCNA,PSMA6,PTEN,RBL1,HUWE1,ELMO1,LSM6,USP32,DCP1A,PRPF4,TP53BP2,PSAP,USP11,YWHAH,ATP6V0D1,SMAD4,HDAC2,PRPF19 |
| 1.896e-03 | -6.27 | GSE43863_DAY6_EFF_VS_DAY150_MEM_TFH_CD4_TCELL_UP | MSigDB lists | GSE43863_DAY6_EFF_VS_DAY150_MEM_TFH_CD4_TCELL_UP | 189 | 44 | 17377 | 2626 |
DDX58,TCF12,PRPF38B,HECA,PARP12,TMEM184B,IVNS1ABP,ACAP1,SIRT2,THRAP3,RGS2,KTN1,RGS1,PDCD10,LRRC8D,FOXN2,ZNF800,ATP6V0D1,SRPK2,TGFB1,FTL,WDR1,ILF3,HNRNPF,ATP6V0A1,KRAS,CYFIP2,ZFAND5,ATP6V1D,GOLGA4,TXNDC16,HNRNPR,MFAP1,DCK,ZNF367,MAFK,SNAP29,STAT1,RBPJ,CDK2,RNF14,CABLES1,CBX4,RNF114 |
| 1.896e-03 | -6.27 | GSE17721_LPS_VS_POLYIC_12H_BMDC_DN | MSigDB lists | GSE17721_LPS_VS_POLYIC_12H_BMDC_DN | 189 | 44 | 17377 | 2626 |
ANKRD27,NSMCE4A,MANBA,ZFP91,RHOC,PCSK7,PXMP2,CCNL2,HCFC1R1,SLC12A9,CPNE3,LMNA,MBD4,GTF2F1,STRBP,THAP4,DUT,RPL19,TAP2,METTL9,AHCYL1,TFG,SEH1L,TIMP2,NCK1,VHL,RAB7A,RPS10,POLR3GL,PRMT2,RFC2,EIF3H,ASF1B,NEU1,IRF5,FBXO21,HHEX,UAP1,TXNDC16,RPS14,NFIL3,DUSP11,SMAD4,ANXA11 |
| 1.896e-03 | -6.27 | GSE41978_ID2_KO_AND_BIM_KO_VS_BIM_KO_KLRG1_LOW_EFFECTOR_CD8_TCELL_DN | MSigDB lists | GSE41978_ID2_KO_AND_BIM_KO_VS_BIM_KO_KLRG1_LOW_EFFECTOR_CD8_TCELL_DN | 189 | 44 | 17377 | 2626 |
UBL3,RAC1,CERK,TPX2,KCTD17,ITGB5,FOXO3,WRB,SLC25A37,ANKRD28,FLAD1,DTL,RRN3,RBM23,ATP2A2,KLHL20,IARS,INPP5A,PPME1,MAVS,MYBL1,RBM15,FAM171A1,LUC7L2,USP34,SOCS5,ZNF672,FAM172A,MRS2,CUL3,ZBED5,CAMSAP1,RRM2,PFKFB3,EIF2AK1,SOX4,ODC1,MTMR3,SERTAD2,MDH1,ZMIZ1,RNF139,ZNF146,S100PBP |
| 1.896e-03 | -6.27 | GSE26030_UNSTIM_VS_RESTIM_TH1_DAY5_POST_POLARIZATION_UP | MSigDB lists | GSE26030_UNSTIM_VS_RESTIM_TH1_DAY5_POST_POLARIZATION_UP | 189 | 44 | 17377 | 2626 |
WASF2,CMAS,ABCA3,ADD1,GXYLT1,ADAM10,ANKH,HEXB,RAB23,LANCL1,FAM8A1,XPR1,RB1,TNS3,ADD3,INPP5A,CNPY4,ANXA5,CDC25B,CNNM3,MSH6,SOCS5,TSHZ1,VOPP1,MAPRE2,TNFAIP3,NARF,MCL1,RAB3IP,PRMT2,PTTG1IP,POLG2,CYB5A,MAN2A2,AHNAK,FNTA,MEGF9,NCOA1,ZMIZ1,RTN3,SNX14,ZMAT3,POT1,S100PBP |
| 1.896e-03 | -6.27 | GSE14308_TH2_VS_TH1_UP | MSigDB lists | GSE14308_TH2_VS_TH1_UP | 189 | 44 | 17377 | 2626 |
GCLM,CORO7,TXN,CASP6,WDYHV1,CUL1,HMGN3,CDK13,BCAT2,SRXN1,FASTKD3,HUWE1,IL6ST,BANF1,PPP6C,FNIP2,RNF19A,ALDH18A1,MAML1,ST8SIA2,POC5,ALDH9A1,PPP1R18,MLEC,TLK1,WDR81,PRKRA,ANLN,CHCHD6,TARS,ANKRD46,PLAA,ORMDL2,WDR11,RBMX,AP1S1,ROCK1,PPP6R2,PPP5C,CHPF2,SLC25A39,ALS2,SMARCD1,TMEM131 |
| 1.896e-03 | -6.27 | GSE17721_CTRL_VS_LPS_24H_BMDC_DN | MSigDB lists | GSE17721_CTRL_VS_LPS_24H_BMDC_DN | 189 | 44 | 17377 | 2626 |
GOLIM4,MRPS2,GORASP1,SLC41A1,SLC2A1,RBM8A,RAB23,NDUFA4,AGFG1,SNRPD3,UBE2I,PMVK,ZADH2,WRNIP1,RAD23A,FKBP1A,PA2G4,ATP6V0B,PSMA6,DDA1,SRI,MRPL21,LRRC59,TNRC18,TSHZ1,ETV3,TMEM39A,ARHGDIB,PTTG1IP,TXNL4A,DDX39A,ODC1,ABCF1,MAGED2,AMZ2,DNAJC10,TPD52L2,MRPL55,CHCHD1,WDR4,RWDD4,RUVBL2,TRAF5,TMEM33 |
| 1.896e-03 | -6.27 | GSE2826_WT_VS_XID_BCELL_UP | MSigDB lists | GSE2826_WT_VS_XID_BCELL_UP | 189 | 44 | 17377 | 2626 |
PPIB,C9orf78,PRPF38B,RECQL,MIF4GD,FAM207A,SRSF6,AP1B1,CDIPT,CMTM6,PABPC4,UBLCP1,MAN1A1,BCAT2,IARS,TNFAIP8,NVL,MCM5,CRAT,HADHB,RNASEH2A,ASB6,PPA1,NCOA2,KDELR1,TK1,SNX2,NEK7,CUL3,GALK2,AURKB,EIF3G,SLC50A1,ISG15,PRIM1,EPB41,DERL1,SLC19A1,TWSG1,SLC25A19,ROCK1,KLHDC4,CHEK2,GCSH |
| 1.896e-03 | -6.27 | GSE2770_UNTREATED_VS_TGFB_AND_IL4_TREATED_ACT_CD4_TCELL_48H_DN | MSigDB lists | GSE2770_UNTREATED_VS_TGFB_AND_IL4_TREATED_ACT_CD4_TCELL_48H_DN | 189 | 44 | 17377 | 2626 |
POLA2,PPIB,RAB14,HSPH1,NDUFV2,HNRNPAB,GORASP1,IVNS1ABP,EIF3D,FLOT1,EBNA1BP2,RAD23A,PRNP,FARSA,PSMA6,TNFAIP8,AP3S2,XPA,CITED2,TMED2,NASP,ELL2,MAPKAPK3,VHL,LYRM1,RPL8,ATXN1,PSMG1,ABCF1,ETS2,HINT1,COX7A2L,DCAF11,SEL1L,TICAM1,TCOF1,ATP6V1C1,LTA4H,PITRM1,LRP8,TUBB,BYSL,DDX42,ZBTB24 |
| 1.896e-03 | -6.27 | GSE8515_CTRL_VS_IL6_4H_STIM_MAC_UP | MSigDB lists | GSE8515_CTRL_VS_IL6_4H_STIM_MAC_UP | 189 | 44 | 17377 | 2626 |
RMND5A,RAB14,CMAS,HJURP,MRPS15,MEF2A,SIKE1,RAB11A,STAM,MCTS1,RAP1A,PSMD1,ZNF473,SNUPN,MEX3C,PPP6C,RP2,CFL1,TMED2,MKLN1,PRIM2,TSPYL4,MRS2,E2F3,FRAT2,SLBP,GALNT7,CDC23,KIF11,EIF4G2,MAP3K4,SMAD2,PLAA,PPP2R5A,C1orf109,QRSL1,MEGF9,TOB1,HRAS,OAZ1,MRPL3,EGLN1,TMEM131,LRCH1 |
| 1.896e-03 | -6.27 | GSE22886_CD8_TCELL_VS_BCELL_NAIVE_UP | MSigDB lists | GSE22886_CD8_TCELL_VS_BCELL_NAIVE_UP | 189 | 44 | 17377 | 2626 |
CTDP1,GLT8D1,LIME1,KLHL21,XAB2,RHOC,FAM129A,MOGS,CERK,TMED3,SLC25A44,FAM8A1,ABHD14A,PA2G4,PSMD1,CITED2,MVP,MYBL1,KCNAB2,TACC3,NIPAL3,TIMM8B,STAU1,GALC,NQO2,DENND1B,MRPL12,ITM2A,MAP7D1,RANGAP1,MTX1,PRMT2,NMT2,OPTN,MAGED2,UAP1,FKBP5,CTSA,CABIN1,RRS1,B4GALT3,ARRB2,RTN3,NRBP1 |
| 1.896e-03 | -6.27 | GSE17721_0.5H_VS_4H_PAM3CSK4_BMDC_DN | MSigDB lists | GSE17721_0.5H_VS_4H_PAM3CSK4_BMDC_DN | 189 | 44 | 17377 | 2626 |
SEPHS2,ZNF207,RPS2,PKP4,TCF3,C16orf87,SLC4A2,LACTB2,EIF1B,SRXN1,FAM192A,RNF121,APLP2,DDA1,POP7,RAD23B,PPP6C,BTF3L4,CAPZA1,LTN1,RNF19A,ATF2,NCOA2,YTHDC1,RB1CC1,NCK1,GOPC,PSPC1,RFFL,MAP4K3,NDUFA7,TANC1,RHOT1,DAPK3,SRSF1,JAK1,RBM25,BRWD1,BCL7C,SAMD8,YY1,NDE1,PFKP,DDX42 |
| 1.897e-03 | -6.27 | Activation of NIMA Kinases NEK9, NEK6, NEK7 | REACTOME pathways | R-HSA-2980767 | 7 | 5 | 10287 | 1696 |
PLK1,NEK6,CCNB1,CCNB2,NEK7 |
| 1.898e-03 | -6.27 | nucleoside triphosphate biosynthetic process | biological process | GO:0009142 | 101 | 27 | 17256 | 2622 |
TGFB1,GALK1,COX5B,SUCLG1,UCK2,LDHA,ATP6V0A1,UCK1,OGDH,ATP5F1B,ADPGK,PKM,ATP5MF,ATP5PF,STOML2,ATP5MC3,CTPS1,TBPL1,IMPDH1,ATP6V0A2,DHTKD1,GPI,CYC1,ATP5F1A,NIPSNAP2,PGAM1,PFKP |
| 1.910e-03 | -6.26 | ALDOC (aldolase, fructose-bisphosphate C) | protein interactions | 230 | 68 | 21 | 17029 | 2761 |
ARHGAP17,PPIB,EWSR1,RAE1,OLA1,GLO1,FKBP2,MCM2,GLOD4,NDUFS4,DUT,PRDX5,NSFL1C,TAGLN2,LMAN1,PGAM1,CDK2,GPD1L,SMAD4,IMPA2,GPX4 |
| 1.910e-03 | -6.26 | PCGF6 (polycomb group ring finger 6) | protein interactions | 84108 | 68 | 21 | 17029 | 2761 |
UBE2D3,CEP170B,USP7,MAX,PCGF6,CSNK2A1,MIER2,EFL1,WDR5,USP21,CBX3,FBRS,RAD18,ZKSCAN1,TFDP1,SS18L1,WDR76,TFDP2,CBX4,HDAC2,RYBP |
| 1.910e-03 | -6.26 | ARFGAP1 (ADP ribosylation factor GTPase activating protein 1) | protein interactions | 55738 | 68 | 21 | 17029 | 2761 |
TK1,RFC3,COPA,RAB23,ARF1,AP1B1,RGS2,MAP1LC3B,REEP5,APP,TFRC,RPL11,FNTA,RABGAP1L,AP2B1,TCEA1,AP2S1,CSNK1D,TMED2,CARM1,KDELR1 |
| 1.913e-03 | -6.26 | MYB (MYB proto-oncogene, transcription factor) | protein interactions | 4602 | 55 | 18 | 17029 | 2761 |
CNOT9,SP100,KAT2A,CHD3,RBX1,HIPK2,ZMYND11,SUMO2,PML,CSNK2A1,UPF2,SND1,WDR5,UBE2I,MEN1,MAPK1,TRIM28,DDB1 |
| 1.918e-03 | -6.26 | RNA_helicase_DEAD_Q_motif | interpro domains | IPR014014 | 37 | 13 | 18492 | 2768 |
DDX28,DDX56,DDX47,DDX24,EIF4A3,DDX20,DDX5,DDX31,DDX39A,DDX52,DDX42,DDX17,DDX23 |
| 1.920e-03 | -6.26 | V$PAX5_01 | MSigDB lists | V$PAX5_01 | 142 | 35 | 17377 | 2626 |
UBE2D3,PRPF38B,CDC40,GOLPH3L,XIAP,PLAGL2,ARFIP2,JMJD6,ARGLU1,HMGN3,RAB11A,POFUT1,XPR1,PAIP2,NRF1,TNFAIP8,INTS12,ZNF710,ZNF800,SENP1,DNAL4,RLIM,TLK1,LNX2,ARHGEF12,ARID1A,GSTCD,EIF4G2,POLR2A,BTBD1,UBTF,CDC27,VCPIP1,MAP3K5,PRPF4B |
| 1.920e-03 | -6.26 | RASHI_RESPONSE_TO_IONIZING_RADIATION_5 | MSigDB lists | RASHI_RESPONSE_TO_IONIZING_RADIATION_5 | 142 | 35 | 17377 | 2626 |
USP7,CTDP1,DNAJC5,DNMT3A,DNAJB2,GADD45G,CIB1,UCK1,KLF13,CSNK2A1,NDUFA4,GYG1,PITHD1,MAT2B,UCHL5,ADCY9,ATP13A3,PELO,ANP32A,NAP1L4,CNOT6L,NCOA2,PLK1,DEAF1,FAM118B,VHL,MAP4K4,CPOX,CDC6,EPB41,SH3BP5,MAP3K4,PEX5,FASTK,PREPL |
| 1.921e-03 | -6.26 | GSE27291_0H_VS_6H_STIM_GAMMADELTA_TCELL_UP | MSigDB lists | GSE27291_0H_VS_6H_STIM_GAMMADELTA_TCELL_UP | 168 | 40 | 17377 | 2626 |
ST13,CLSPN,MRPS15,SRSF6,GLUD1,ARGLU1,SLC4A2,PRPF39,BECN1,PABPC4,NDUFS7,FZD6,ZNF275,CNOT3,RPL11,WRNIP1,ZKSCAN1,AHSA1,PDCD2,RNASEH2A,NSUN4,PPA1,LONRF3,SUGP2,PRKAR1B,SUMF2,UBE4B,SRSF5,TARS,ZMYM3,NSA2,BOLA3,SEPT1,RPS27A,STAT6,ERGIC3,NFIL3,TYW5,CENPT,HIGD2A |
| 1.923e-03 | -6.25 | Colorectal cancer | KEGG pathways | ko05210 | 60 | 19 | 7161 | 1149 |
TGFB1,RHOA,RAF1,AKT2,RAC1,KRAS,CYCS,APPL1,MAPK3,SMAD2,BIRC5,AXIN1,PIK3R2,MSH2,AXIN2,BCL2,MAPK1,SMAD4,MSH6 |
| 1.923e-03 | -6.25 | Colorectal cancer | KEGG pathways | hsa05210 | 60 | 19 | 7161 | 1149 |
TGFB1,RHOA,RAF1,AKT2,RAC1,KRAS,CYCS,APPL1,MAPK3,SMAD2,BIRC5,AXIN1,PIK3R2,MSH2,AXIN2,BCL2,MAPK1,SMAD4,MSH6 |
| 1.925e-03 | -6.25 | Resolution of D-loop Structures through Holliday Junction Intermediates | REACTOME pathways | R-HSA-5693568 | 34 | 13 | 10287 | 1696 |
RAD51C,PALB2,RAD51AP1,XRCC2,RMI2,TOP3A,XRCC3,BRCA1,BLM,GEN1,RMI1,SPIDR,RAD51D |
| 1.927e-03 | -6.25 | liver-other-hepatoblastoma | COSMIC cancer mutations | liver-other-hepatoblastoma | 33 | 12 | 17385 | 2587 |
GNAS,CDKN2C,NRAS,SF3B1,AXIN1,PTPN11,KRAS,KMT2C,H3F3A,STAT3,HRAS,CDKN2A |
| 1.927e-03 | -6.25 | hepatoblastoma | COSMIC cancer mutations | hepatoblastoma | 33 | 12 | 17385 | 2587 |
GNAS,CDKN2C,NRAS,SF3B1,AXIN1,PTPN11,KRAS,H3F3A,KMT2C,STAT3,HRAS,CDKN2A |
| 1.928e-03 | -6.25 | guanyl ribonucleotide binding | molecular function | GO:0032561 | 387 | 81 | 17224 | 2647 |
RHOG,RAB14,RAB11B,RAC1,OLA1,TPX2,RRAGC,GLUD1,EFL1,MIEF1,RAB21,RAB8A,RAP1A,CDC42,SAR1A,RALB,RAB35,RAB4A,DNM2,UPRT,SEPT11,SUCLG2,RP2,EIF5,ARL5A,RHOBTB3,NRAS,SEPT9,CGAS,RAB7A,RAB1A,ARL5B,RAB5B,RAB22A,LSG1,RAB2B,ARF4,RHEB,DAP3,SEPT1,RAB24,GUCY1B1,TUBB,RHEBL1,ANXA6,RHOC,GSPT2,RAB23,ARFIP2,RAB6A,ARF1,IFT27,RAB11A,GFM2,RTKN,GTPBP3,ARF5,EFTUD2,DAPK1,GNAI2,RHOA,NOA1,TUFM,GTPBP4,SEPT8,BMS1,KRAS,RIT1,RHOT1,SEPT7,RHOT2,GUF1,RHOB,MFN2,GNAS,ADSS,GNA12,RAB18,PRPS2,EHD4,HRAS |
| 1.931e-03 | -6.25 | GO_SUPRAMOLECULAR_FIBER | MSigDB lists | GO_SUPRAMOLECULAR_FIBER | 601 | 117 | 17377 | 2626 |
ZNF207,SKA3,CYLD,DYNLL1,RAC1,XIAP,TPX2,SIRT2,KIF2C,MAP1LC3B,STMN1,BIRC2,KIFC1,CALM2,DST,NEK6,SYNM,WDR44,DPYSL2,MTA1,KIF14,RCSD1,DNM2,KIF22,CORO1A,KCNAB2,DNAL4,DCTN1,PLK1,CCT2,PSRC1,MAPRE2,SEPT9,BIRC3,PBXIP1,CUL3,TUBGCP5,KIF15,NARF,EZR,WIPF1,NUSAP1,AURKB,EML4,SERP1,KRIT1,DPYSL3,KIF2A,CDC16,MID1IP1,KIF18B,AXIN1,MAP4,GAS2,DVL1,REEP4,DYNC1LI2,CSNK1D,TUBB,KIF3B,HSPH1,MAPRE1,KLHL21,DCTN2,KLC1,KIF23,RACGAP1,HAUS4,PAWR,MYO9B,CSNK1A1,RAB11A,TUBGCP2,HAUS2,NEIL2,SPAG5,LMNA,JAKMIP1,KIF5B,SLC1A4,CENPJ,KIF13B,AXIN2,PRC1,GTSE1,ARHGEF2,KIFAP3,KNTC1,NCOA2,MYO5A,NUDC,ASPM,NEK7,WDR1,PARP4,CAMSAP1,WDR81,KIF11,MACF1,MAP2K2,CCT8,MARK2,DAPK3,HAUS8,TSC1,KEAP1,KIF18A,GOLGA2,CDC27,TTLL4,BIRC5,ODF2,LRPPRC,PKD2,NDE1,IGBP1,BYSL |
| 1.935e-03 | -6.25 | - | gene3d domains | 1.25.10.10 | 191 | 46 | 8148 | 1295 |
NOP9,PKP4,TRIP12,SF3B1,SCYL1,DNAAF5,XPO7,AP1B1,NCAPG,COPG2,SCYL2,HEATR5B,ZER1,CEP104,PSMD2,PSMD1,CTNNBL1,PPP4R1,TNPO2,AP2B1,LTN1,TNPO3,KIFAP3,SCYL3,USO1,BTAF1,LRBA,TEX10,ARID1A,ARMC8,AP4E1,SYMPK,CIP2A,CAND1,CNOT9,INF2,KPNA4,KPNA1,HSPBP1,PLAA,PPP2R5A,ELMO1,CAB39,SIL1,KPNA2,ECPAS |
| 1.936e-03 | -6.25 | H2AFY (H2A histone family member Y) | protein interactions | 9555 | 86 | 25 | 17029 | 2761 |
UNK,MAX,SUZ12,MECP2,CUL3,MYH9,NSD3,NFATC2,BRCA1,DIDO1,VDAC1,APP,LMNA,HMGN2,XRCC5,CBX3,ZNF428,HSPA4,PHF14,H2AFX,RBPJ,H3F3A,ATF2,IFI16,HDAC2 |
| 1.936e-03 | -6.25 | HDLBP (high density lipoprotein binding protein) | protein interactions | 3069 | 86 | 25 | 17029 | 2761 |
PRKDC,DYNLL1,DHX9,CSNK2A1,UBE4B,EIF2A,ATP6V1B2,KIF11,SDHA,KCMF1,VPS25,SAC3D1,XRCC5,UPF1,SYNCRIP,WDR59,YBX1,TTC4,FAU,CDK2,ZNF598,HDHD2,SMAD4,VPS29,CDC5L |
| 1.944e-03 | -6.24 | regulation of translational initiation | biological process | GO:0006446 | 77 | 22 | 17256 | 2622 |
MIF4GD,POLR2G,NCK1,CDC123,PPP1R15B,HABP4,AGO2,POLR2D,YTHDF3,EIF2AK1,EIF2AK4,EIF1B,EIF4H,EIF4G2,METTL3,RBM4,EIF3H,PAIP1,PAIP2,EIF3K,GLE1,EIF5 |
| 1.944e-03 | -6.24 | negative regulation of mRNA metabolic process | biological process | GO:1903312 | 77 | 22 | 17256 | 2622 |
RBM42,SRSF6,DHX9,CIRBP,RNPS1,SECISBP2,THRAP3,MAPK14,PAIP1,HNRNPA2B1,SYNCRIP,RBMX,SRSF4,AXIN2,E2F1,CTR9,TRA2B,YBX1,TARDBP,TOB1,PABPC1,SRSF10 |
| 1.945e-03 | -6.24 | regulation of viral transcription | biological process | GO:0046782 | 63 | 19 | 17256 | 2622 |
CTDP1,POLR2I,POLR2G,POLR2L,POLR2K,TRIM11,DHX9,POLR2D,SMARCA4,CHD1,POLR2A,GTF2F1,TFAP4,POLR2J,ZNF639,MDFIC,TARDBP,TRIM32,TRIM14 |
| 1.947e-03 | -6.24 | MHC class II antigen presentation | REACTOME pathways | R-HSA-2132295 | 103 | 29 | 10287 | 1696 |
KIF3B,DYNLL1,RAB7A,DCTN2,KIF15,KLC1,KIF23,RACGAP1,KIF2C,ARF1,AP1B1,KIF11,SEC31A,KIF2A,KIF5B,CTSL,CTSS,KIF18A,SEC24C,DNM2,AP1M1,AP2B1,AP1S1,CTSA,KIF22,KIFAP3,AP2S1,DYNC1LI2,DCTN1 |
| 1.948e-03 | -6.24 | Glucose transport | REACTOME pathways | R-HSA-70153 | 46 | 16 | 10287 | 1696 |
NDC1,NUP188,RAE1,SLC2A1,NUP54,NUP155,SLC50A1,NUP205,NUP210,NUP107,NUP153,NUP62,NUP85,NUP58,SEH1L,AAAS |
| 1.951e-03 | -6.24 | FOXS1 (forkhead box S1) | protein interactions | 2307 | 77 | 23 | 17029 | 2761 |
TOR3A,HNRNPUL2,WDR18,WDHD1,DNAJC9,SMC2,FXR1,PRPF39,DDX39A,APP,ZFR,PPP2CA,CMSS1,MAGT1,ACOX1,RBMX,AKAP8,IARS2,ANAPC7,ZNF598,PPP2R2D,MRPL3,HDAC2 |
| 1.951e-03 | -6.24 | MGMT (O-6-methylguanine-DNA methyltransferase) | protein interactions | 4255 | 77 | 23 | 17029 | 2761 |
DDX24,PRKDC,CSNK2A1,ORC1,PKM,CCNB1,MCM2,PRKACA,PSMD9,EIF3H,HNRNPA2B1,PCNA,RPLP1,MSH2,ANP32E,YWHAZ,DDX5,ACTB,PRPF4,FBL,CDK2,CDK12,SSRP1 |
| 1.951e-03 | -6.24 | UBE2E2 (ubiquitin conjugating enzyme E2 E2) | protein interactions | 7325 | 77 | 23 | 17029 | 2761 |
UBE2E2,RBX1,RNF25,XIAP,CUL3,BRCA1,DAZAP2,TRIM28,APP,RNF103,DTL,MDM2,SIAH1,DDA1,TRIM32,RNF19A,RNF14,HDAC2,RNF5,RNF114,SRPK2,RLIM,PDLIM2 |
| 1.951e-03 | -6.24 | AGAP1 (ArfGAP with GTPase domain, ankyrin repeat and PH domain 1) | protein interactions | 116987 | 77 | 23 | 17029 | 2761 |
TK1,RHOA,NF1,FAM53C,DENND4C,RAC1,MIER2,RAB3IP,ARF1,USP21,APP,GIGYF1,EDC3,RTKN,AFDN,ZBTB21,CDC42,FAM110A,GUCY1B1,KIF13B,CBWD1,PRPF4,CDC25B |
| 1.951e-03 | -6.24 | KPNA3 (karyopherin subunit alpha 3) | protein interactions | 3839 | 77 | 23 | 17029 | 2761 |
IER2,FTL,ZCCHC10,RPRD1A,KMT2E,MECP2,USP42,CUL3,BRCA1,FAM50B,LMNA,MAT2B,KPNA4,MTA1,CDKN1B,KPNA2,NUP153,KIF22,MVP,RBBP4,ARRB2,COIL,ZBTB24 |
| 1.952e-03 | -6.24 | GO_HISTONE_H3_ACETYLATION | MSigDB lists | GO_HISTONE_H3_ACETYLATION | 41 | 14 | 17377 | 2626 |
SAP130,IRF4,MBIP,KAT2A,BRPF3,KAT7,LDB1,ELP4,TAF5L,TAF6L,TAF12,WDR5,SUPT7L,MEAF6 |
| 1.955e-03 | -6.24 | TGCACTT,MIR-519C,MIR-519B,MIR-519A | MSigDB lists | TGCACTT,MIR-519C,MIR-519B,MIR-519A | 422 | 86 | 17377 | 2626 |
RORB,HECA,NF1,DAZAP2,LCLAT1,PAPOLA,ASAP2,AHCTF1,KDM2A,MTMR4,DPYSL2,SOCS6,DNM2,TAF5L,CDK12,ARID4A,SP3,TIMP2,CELSR2,GOPC,CUL3,TOPORS,BICD2,SOX4,RAB5B,STK17B,BRWD1,LIMK1,HPS5,STK38,FASTK,ZNF367,MAP4,OGT,POLQ,MAPRE1,MECP2,ZFP91,HABP4,PRKAA1,KIF23,SUMF1,ASXL2,DNAJB9,JAKMIP1,PTPN2,GNS,RB1,KLHL20,FJX1,BTF3L4,ST8SIA2,MAML1,STAT3,SMC4,PPP3CA,ABHD2,CIC,WDR1,PPP1R21,ATP2C1,SRSF5,EIF4G2,GOSR1,MASTL,SH3BP5,CACNB1,TMEM127,SERTAD2,TMEM168,L3MBTL3,CSNK1G1,MAPK6,E2F1,USP32,PKD2,SLAIN1,CNOT6,DDX5,MAP3K5,PPP6R2,PPP6R3,BTBD10,CDK2,CPEB2,NIPA1 |
| 1.955e-03 | -6.24 | MULLIGHAN_MLL_SIGNATURE_2_DN | MSigDB lists | MULLIGHAN_MLL_SIGNATURE_2_DN | 265 | 58 | 17377 | 2626 |
IER2,AGRN,LUZP1,MRPS2,TCF3,CHD1L,OLA1,C5orf30,PTP4A3,NIT2,AP1B1,DCUN1D4,PPP1R16B,RAB11A,APP,KTN1,STAM,MAN1A1,GTPBP3,CLIC4,ATP2A2,GSDMB,SRI,DAPK1,TNPO2,SEPT11,KIFAP3,TTC3,FAM171A1,EEF1D,USP34,FDFT1,ANKLE2,MAPRE2,HEMK1,SEPT9,HMGN4,NET1,LYRM1,ATP2C1,TEX10,ITM2A,PITPNB,MACF1,SERP1,MATR3,RPL36,JAK1,SYNCRIP,POLE,HINT1,ELMO1,WDR59,NR2F2,NUDT11,IFI16,PDCD4,N4BP2L2 |
| 1.959e-03 | -6.24 | TPM3 (tropomyosin 3) | protein interactions | 7170 | 133 | 35 | 17029 | 2761 |
ADD1,THOC1,MYH9,COX4I1,IKBIP,STMN1,PARK7,FBXO5,OIP5,PSMA6,DAPK1,OSTF1,CYC1,AHCYL1,DVL2,SEPT9,CDC123,TLK1,CUL3,CAPZA2,BRCA1,VDAC1,MCM2,ANLN,SF3A2,PRDX1,MAGED2,ATP1A1,SEC23IP,MYO18A,COX5A,ACTB,FKBP5,CDK2,SGF29 |
| 1.959e-03 | -6.24 | MAX (MYC associated factor X) | protein interactions | 4149 | 133 | 35 | 17029 | 2761 |
CCDC93,RECQL,MAX,RPL35,RPRD1A,KAT2A,MTERF1,FOXK1,MECP2,PCGF6,CSNK2A1,RCOR1,NUF2,MXD4,WDR5,PSMD9,MAPK14,GIT2,HMG20A,MXD1,PLEKHF2,SAP130,OIP5,RPA2,USF1,GRIPAP1,RABGAP1L,TFDP1,ARNTL,MSH2,H2AFY,FUS,YY1,SMAD4,EEF1D |
| 1.960e-03 | -6.23 | GSE21063_WT_VS_NFATC1_KO_8H_ANTI_IGM_STIM_BCELL_DN | MSigDB lists | GSE21063_WT_VS_NFATC1_KO_8H_ANTI_IGM_STIM_BCELL_DN | 184 | 43 | 17377 | 2626 |
MIB2,TCF12,RMND5A,UNK,SART1,MPHOSPH8,FAM207A,MCCC1,PCSK7,KLC1,CDK11B,PDCD7,C19orf48,LCLAT1,PMVK,ANKRD28,CYHR1,AKAP8,ARHGEF1,SLC44A1,TNPO2,RPF2,UPF2,FAM76B,RLIM,LDB1,FRAT2,DIDO1,CBFA2T2,GOSR1,RHOT2,PSMB3,RXRB,ANKRD10,TSC1,ZNF777,FASTK,ZNF436,GALNT10,IDH3B,USF2,NMD3,CCDC137 |
| 1.960e-03 | -6.23 | GSE14350_TREG_VS_TEFF_UP | MSigDB lists | GSE14350_TREG_VS_TEFF_UP | 184 | 43 | 17377 | 2626 |
RAB14,ASH1L,CXXC1,TRIM11,MUM1,TMX4,CERK,ENSA,MEF2A,ASXL2,LCLAT1,RAPGEF6,ARID1B,HMG20A,TRIM65,C14orf119,CRKL,PTEN,CISD2,MOB1A,RNF169,WDR41,KDM3B,AGGF1,FAM172A,ZMYND11,BTG2,PRKDC,KRAS,MTMR12,MAP4K3,TAZ,SLTM,CYB5A,TSC1,TBC1D17,GRIPAP1,STK38,PROSER1,OGT,MEGF9,FBXL3,TMEM131 |
| 1.960e-03 | -6.23 | GSE27786_BCELL_VS_NKTCELL_DN | MSigDB lists | GSE27786_BCELL_VS_NKTCELL_DN | 184 | 43 | 17377 | 2626 |
GMFG,TRIP12,LUZP1,NOP2,ANXA6,AGTRAP,ANKH,TMX4,FLOT1,MAPK14,FAM8A1,RGS1,GOLM1,BDH1,SRI,ORAI1,TECR,CNNM3,PABPC1,SLC25A1,SMC4,ABCC5,DCTN1,ZDHHC18,CCDC138,KLF10,PRKDC,RPS10,MAP7D1,RIT1,PTTG1IP,GOSR1,PDLIM1,VPS26B,CHD3,CSNK1G1,COX8A,MBOAT1,AKNA,TMEM159,YWHAH,NGLY1,MZT2B |
| 1.960e-03 | -6.23 | GSE20152_SPHK1_KO_VS_WT_HTNFA_OVERXPRESS_ANKLE_UP | MSigDB lists | GSE20152_SPHK1_KO_VS_WT_HTNFA_OVERXPRESS_ANKLE_UP | 184 | 43 | 17377 | 2626 |
UBE2D3,USP7,IER2,ASH1L,FAM208B,RRP15,AGFG1,RAPGEF6,RGS1,MOAP1,IRF4,PPME1,PHF14,ZNF335,DCP1A,ANXA5,RBM3,TTC4,MAP3K14,RHOBTB3,TMEM39A,ERF,GABPA,RAB7A,TSPAN31,PFKFB3,TOPORS,SRSF5,AZI2,RAB1A,PRKRA,LUC7L,RAB22A,RHEB,ARF4,TFEB,HGS,FBXO28,TAB2,CORO1C,KPNA2,CHPF2,CBX4 |
| 1.960e-03 | -6.23 | GSE1925_3H_VS_24H_IFNG_STIM_MACROPHAGE_DN | MSigDB lists | GSE1925_3H_VS_24H_IFNG_STIM_MACROPHAGE_DN | 184 | 43 | 17377 | 2626 |
HIVEP3,WASF2,IER2,PRKAB1,ADD1,CXXC1,SRGN,NACA,PCSK7,BCL2L1,PHC2,CALM2,GSTK1,ITGB8,FBXO7,TCEA1,FAM171A1,SPTAN1,RPL35,MAPRE2,AATF,DCAF8,MAN1B1,MFNG,EIF2AK1,RANGAP1,OTUD3,RPL27A,HAGH,ISG15,PSMC4,HMGN2,UTP20,HGS,SCAP,HIPK2,AXIN1,RPS14,APPL2,AEN,TAF12,PPP6R2,ATP6V1C1 |
| 1.960e-03 | -6.23 | GSE41867_NAIVE_VS_DAY8_LCMV_ARMSTRONG_EFFECTOR_CD8_TCELL_UP | MSigDB lists | GSE41867_NAIVE_VS_DAY8_LCMV_ARMSTRONG_EFFECTOR_CD8_TCELL_UP | 184 | 43 | 17377 | 2626 |
COMMD10,FGFR1OP,ANKRD13D,SARNP,UGP2,POLR2K,SLC41A1,GNE,HEXB,FKBP2,CUTC,COMMD8,FAM8A1,KTN1,RSAD1,ARL6IP6,MCTS1,HNRNPA2B1,C1GALT1,PDCD10,AP3S2,GEMIN6,RPF2,PRADC1,ARL5A,JMJD4,ANKLE2,ARHGAP17,RBX1,CPOX,ACSL3,TTC33,SERP1,GLOD4,RDH11,FAS,VEZF1,FBXO21,MID1IP1,CDCA4,VCPIP1,DUSP11,NDUFS5 |
| 1.960e-03 | -6.23 | PRC2_EED_UP.V1_DN | MSigDB lists | PRC2_EED_UP.V1_DN | 184 | 43 | 17377 | 2626 |
POLA2,HIVEP3,GALK1,NUP188,MCM10,CLSPN,TSC2,C1orf112,DNAJB2,VAV2,CDCA8,KIF23,THRAP3,ORC1,TUBGCP2,FBXL6,MCM5,DDX31,CORO1A,GLE1,RNF19A,SLC35C2,GNAI2,PHKG2,TACC3,HP1BP3,PLK1,MYBL2,PACS1,RANGAP1,AMDHD2,MCM2,SYMPK,ASF1B,ANKZF1,TBL3,ODF2,PRMT7,USP20,FKBP5,XRCC3,OSGEPL1,ARRB2 |
| 1.960e-03 | -6.23 | GSE3039_NKT_CELL_VS_B1_BCELL_DN | MSigDB lists | GSE3039_NKT_CELL_VS_B1_BCELL_DN | 184 | 43 | 17377 | 2626 |
DNMT3A,MAGED1,CDT1,CHD1L,RRM1,COX4I1,FKBP2,HDDC2,LMNA,TMCC3,ANKRD28,SUB1,ATIC,RPL19,TMEM9,TPCN1,MYO5A,TACC3,GINS1,SNX8,FYTTD1,CCT2,MND1,TIMP2,TK1,SNX2,ASPM,TUFM,MRPS10,TMEM147,VKORC1,USP36,GNA12,TMEM54,PRDX3,CHD3,ZNF330,QARS,NAGLU,H2AFX,FAM126A,PURA,TUBB |
| 1.960e-03 | -6.23 | GSE22886_NAIVE_BCELL_VS_NEUTROPHIL_DN | MSigDB lists | GSE22886_NAIVE_BCELL_VS_NEUTROPHIL_DN | 184 | 43 | 17377 | 2626 |
TXN,PLXNC1,CKLF,B4GALT5,FAM129A,SRGN,FLOT1,ATP6V1B2,CFLAR,PHC2,VASP,RALB,ARPC5,PPP4R1,PPCDC,TALDO1,CLTB,TMBIM1,IMPA2,S100A6,AMPD2,ZDHHC18,TIMM8B,FAM49B,MAPKAPK3,PPT1,NQO2,FRAT2,USP10,MCL1,MTX1,SH3GLB1,MYO1F,FAS,ABHD5,WAS,PPP2R5A,PRDX3,NFIL3,CTBS,IMPDH1,MEGF9,RTN3 |
| 1.960e-03 | -6.23 | GSE21670_UNTREATED_VS_IL6_TREATED_STAT3_KO_CD4_TCELL_DN | MSigDB lists | GSE21670_UNTREATED_VS_IL6_TREATED_STAT3_KO_CD4_TCELL_DN | 184 | 43 | 17377 | 2626 |
SRM,NOP2,HNRNPAB,DHPS,WDYHV1,URB2,ARID5A,FLOT1,GTF3A,IL21R,RAPGEF6,NUP205,PNO1,PPP1R3B,CLUAP1,ATIC,RPF2,AHCY,POLR1B,UBE3C,ALDH18A1,STAT3,SEH1L,LARS,CCT2,KAT2A,SCFD2,GTPBP4,LDHA,NARF,PFKFB3,DCTD,RFC2,MAT2A,UTP20,HNRNPR,CTSA,RRS1,CDK2,LRP8,GPATCH4,HDAC2,BYSL |
| 1.960e-03 | -6.23 | GSE11961_MEMORY_BCELL_DAY40_VS_GERMINAL_CENTER_BCELL_DAY40_DN | MSigDB lists | GSE11961_MEMORY_BCELL_DAY40_VS_GERMINAL_CENTER_BCELL_DAY40_DN | 184 | 43 | 17377 | 2626 |
SLC12A7,ABCA3,CORO7,NOP2,MANBA,MAGED1,ADCK5,SLC35B1,SLC25A44,SDHA,KCMF1,ARID1B,HADHB,ORAI1,RPN2,FNIP2,ZNF710,ENPP4,POLR2I,POLR2G,ATG9A,SIGMAR1,VHL,SCFD2,LRRC1,GALNT7,METTL22,ERC1,MFN2,IWS1,EPRS,BRD2,TXNDC16,RBM47,TTLL4,ZNF367,ARAP1,MDH1,RBPJ,CCDC125,GCSH,SMARCD1,STARD3NL |
| 1.960e-03 | -6.23 | GSE26290_WT_VS_PDK1_KO_ANTI_CD3_AND_IL2_STIM_CD8_TCELL_DN | MSigDB lists | GSE26290_WT_VS_PDK1_KO_ANTI_CD3_AND_IL2_STIM_CD8_TCELL_DN | 184 | 43 | 17377 | 2626 |
DDX58,BCCIP,WASF2,TCF12,CCNC,MCCC1,AGPAT1,PTP4A3,NKRF,NANS,TWF2,PARN,RSAD1,PIP5K1C,PA2G4,COQ4,PRDM4,POP7,DNM2,SS18L1,MOB1A,TALDO1,LRRC59,EBAG9,PDPK1,TMEM115,ACP2,FAM49B,COQ10B,AZI2,RAB5B,RHOB,RBM38,RXRB,TMEM184C,TMEM127,HHEX,TIMM13,TTC13,TBL3,ODF2,ARNTL,SMARCD1 |
| 1.970e-03 | -6.23 | CREB3 (cAMP responsive element binding protein 3) | protein interactions | 10488 | 192 | 47 | 17029 | 2761 |
CDS2,NDUFB6,TMEM203,SEC61G,TMEM243,TAP1,SLC39A13,RAB23,AGPAT3,SLC29A1,BCL2L1,LMNA,ABHD16A,BCAT2,DECR1,RIMS3,BCAP29,SCAMP4,TECR,SLC35C2,FAM3A,CNPY3,TMEM14C,MRPL57,MYO5A,ACSL5,TMEM115,APH1A,UHRF1BP1,VKORC1,KRTCAP2,SLC50A1,RHEB,ALG3,TRIM26,TMEM54,NFIL3,FAM3C,OGT,CEBPG,ATP6V0C,CYBC1,DNAJC30,CHMP7,TMEM14A,PTDSS1,ACSF2 |
| 1.973e-03 | -6.23 | Survival motor neuron (SMN) complex | KEGG pathways | hsa_M00426 | 10 | 6 | 7161 | 1149 |
GEMIN5,DDX20,GEMIN6,GEMIN4,STRAP,GEMIN7 |
| 1.973e-03 | -6.23 | Methionine degradation | KEGG pathways | hsa_M00035 | 10 | 6 | 7161 | 1149 |
MAT2B,AHCY,DNMT3A,AHCYL1,DNMT1,MAT2A |
| 1.973e-03 | -6.23 | Survival motor neuron (SMN) complex | KEGG pathways | M00426 | 10 | 6 | 7161 | 1149 |
GEMIN5,DDX20,GEMIN6,GEMIN4,STRAP,GEMIN7 |
| 1.973e-03 | -6.23 | Methionine degradation | KEGG pathways | M00035 | 10 | 6 | 7161 | 1149 |
MAT2B,AHCY,DNMT3A,AHCYL1,DNMT1,MAT2A |
| 1.975e-03 | -6.23 | dsRBD_dom | interpro domains | IPR014720 | 21 | 9 | 18492 | 2768 |
CDKN2AIP,STAU1,STRBP,DGCR8,DUS2,ILF3,DHX9,NKRF,PRKRA |
| 1.975e-03 | -6.23 | Ribosomal_S5_D2-typ_fold_subgr | interpro domains | IPR014721 | 21 | 9 | 18492 | 2768 |
GALK1,RPS2,EFTUD2,PMS2,TOP2B,EFL1,GALK2,LONP2,GFM2 |
| 1.975e-03 | -6.23 | GSE32255_WT_UNSTIM_VS_JMJD2D_KNOCKDOWN_4H_LPS_STIM_DC_UP | MSigDB lists | GSE32255_WT_UNSTIM_VS_JMJD2D_KNOCKDOWN_4H_LPS_STIM_DC_UP | 163 | 39 | 17377 | 2626 |
MIB2,NF1,ARID5A,UCK2,MED13L,PDCD7,COMMD8,BZW2,LRRC14,C1GALT1,NUP210,INTS7,ZNRF2,OSTF1,NUP153,RNF19A,FOXK1,RPL8,LRRC8A,PFKFB3,ICAM2,PDE3B,KDM3A,RPS9,RBM38,RXRB,RPL37,PFDN5,PEX5,TTC13,PDLIM1,DCK,RNF38,TCOF1,PDLIM5,TRAF5,SMURF1,TSPAN5,RNF114 |
| 1.975e-03 | -6.23 | GSE34156_NOD2_LIGAND_VS_NOD2_AND_TLR1_TLR2_LIGAND_6H_TREATED_MONOCYTE_UP | MSigDB lists | GSE34156_NOD2_LIGAND_VS_NOD2_AND_TLR1_TLR2_LIGAND_6H_TREATED_MONOCYTE_UP | 163 | 39 | 17377 | 2626 |
CDS2,MAGEH1,SARNP,C19orf53,SLC41A1,REPS1,RPAIN,RPL11,WRNIP1,STRBP,KDM2A,WDR44,RBM34,ZNHIT6,RPL19,TTC3,ACAD8,FAM86C1,FBL,ZNF770,FTSJ3,FGFR1OP2,SP3,TTPAL,YTHDC1,CDKN2AIP,JTB,UTP15,RPL38,PPWD1,MAK16,RPSA,NSA2,CERS6,PDRG1,TRIM52,C11orf1,COIL,ANAPC4 |
| 1.976e-03 | -6.23 | RNA polymerase | KEGG pathways | hsa03020 | 31 | 12 | 7161 | 1149 |
POLR2I,POLR2G,POLR2L,POLR2J,POLR2K,POLR2D,POLR3GL,POLR1B,ZNRD1,POLR3K,TWISTNB,POLR2A |
| 1.976e-03 | -6.23 | RNA polymerase | KEGG pathways | ko03020 | 31 | 12 | 7161 | 1149 |
POLR2I,POLR2G,POLR2L,POLR2J,POLR2K,POLR2D,POLR3GL,POLR1B,ZNRD1,POLR3K,POLR2A,TWISTNB |
| 1.979e-03 | -6.23 | Kinesins | REACTOME pathways | R-HSA-983189 | 42 | 15 | 10287 | 1696 |
KIFC1,KIF2A,KIF5B,KIF3B,KIF18A,KIF18B,KIF13B,KIF15,KLC1,KIF23,RACGAP1,KIF22,KIFAP3,KIF2C,KIF11 |
| 1.980e-03 | -6.22 | CD44 (CD44 molecule (Indian blood group)) | protein interactions | 960 | 114 | 31 | 17029 | 2761 |
SLC39A9,AMPD2,GTF3C6,CDC40,CHERP,ATG9A,XAB2,VHL,PHRF1,DYNLL1,SRGN,VAV2,EZR,MYH9,ARHGEF12,CDC73,EPB41,CSK,SNX18,OSBPL8,ARHGEF1,GMEB1,ITGB1,HADHB,TNPO2,AQR,ATF2,STAT3,NIPSNAP2,CDC5L,TMEM160 |
| 1.986e-03 | -6.22 | carcinoid-endocrine_tumour | COSMIC cancer mutations | carcinoid-endocrine_tumour | 7964 | 1253 | 17385 | 2587 |
ZBTB10,TSC2,HEXB,LACTB2,CCNL2,FBXO22,EEF2K,CDKN2C,NAPG,THAP4,RAD23B,MECR,AP1M1,DNM2,UPRT,MGAT5,USP34,CCDC57,RHOBTB3,NRAS,KIF15,WDHD1,MIER2,DIDO1,WBP1,RAB22A,KRIT1,AHNAK,SMAD2,RAD18,PDRG1,MPV17,COX5A,RNASEL,SMAD1,ZNF75A,ANXA11,PDCD4,SLC25A33,ZNF720,HIVEP3,CLSPN,MUM1,TRIO,DHX9,HAUS4,EIF2AK4,APH1B,PARN,CDC73,MYL6B,COPB2,ATG4A,RIMS3,EFTUD2,MVP,NUP85,PHKG2,NSUN4,PPA1,LUC7L2,EIF3L,AGGF1,FOXK1,MTA2,TYW1,GTPBP4,SSR2,ITM2A,USP10,MAP7D1,MRPL16,ELK1,SFXN5,FNTA,KPNA1,TXNDC16,PDLIM1,TYW5,WIPI2,TMEM159,PDLIM5,ACSF2,MRPL3,ALS2,FAM72D,TRIM41,POC1A,PTTG1,ANK3,VTI1A,TPX2,INO80E,LCLAT1,GLRX3,KIAA1147,ABHD16A,ZNF420,AHCTF1,TBC1D22A,SH3BP1,MTA1,UBA5,NSFL1C,SEPT11,ZC3H3,RPRD1B,ARL5A,SNX8,SEC61B,ERMP1,POLR2L,FAM118B,GOPC,CRNKL1,CIRBP,E2F3,PFKFB3,GORAB,TANC1,RAB1A,GIGYF1,TMEM184C,CORO1C,NSMCE2,CAMKMT,RNF38,SNRPG,PPP5C,USP13,COMMD10,MZT1,ZNF445,ZFP91,HABP4,TRMT6,CCM2,FLOT1,ATG2B,IFT27,SLC25A43,GOLM1,RPA2,ZBTB45,PDCD10,CLIC4,ITGB8,COQ4,CBWD2,HUWE1,ARHGEF1,ANXA5,LTN1,UBE3B,ST8SIA2,FBXL19,STAU1,DDX24,TACC1,LLPH,RAB3IP,TTC33,PICALM,UTP20,SLC19A1,ACOX1,FAM3C,THAP5,WDR13,FAM129A,YTHDC2,SND1,PAPOLA,CREM,TET3,FANCL,RAB8A,NUP210,NT5DC1,IL6ST,SLC44A1,NOC2L,MTPN,ASB6,TACC3,RYBP,VPS13B,PLK1,PTPN18,CELSR2,CDC6,EAF2,LSG1,TRIM4,TRAM2,FBXO28,AGPAT2,ZNF367,ADAM9,KPNA2,PRPF4,BEND6,NGLY1,POT1,MYL12B,NUMB,RMND5A,CENPF,NKD2,SDC2,ADCK5,CDK13,RAB6A,NCKAP1,RSAD1,ARID1B,TNS3,CCP110,MBD2,CTR9,MRPL48,LRSAM1,NTPCR,ABHD2,DCAF8,ACSL3,MAP4K3,METTL22,STYXL1,APPL1,RBM38,NMT2,HAUS8,SDHB,PCM1,GALNT2,TMEM168,NLRC5,SIL1,DTD1,BTBD10,MYO9A,CCNB2,UNC13C,USP7,TRAF7,SUCLG1,ARID2,NDUFAF2,TMX4,TOR1AIP1,TM9SF3,ZFYVE21,LYN,VAV1,OIP5,NRF1,PSMA6,ZNF473,WDR44,PPME1,EFCAB11,TARDBP,AHCYL1,LMAN1,CTDSP2,SNX25,KDM3B,MND1,CLCN3,POLR2G,PPT1,ANKRD33B,PPIE,NUP155,EIF3H,IDE,RBL1,STK38,FASTK,UHRF2,AP1S1,XRCC3,CHMP4B,SMAD4,PARD3,SLC30A9,NADSYN1,CMAS,PDAP1,TMX3,SLC12A9,SCYL2,TUBGCP2,HOMER1,WBP1L,POLR1B,ORC3,RPRD1A,TOP3A,ARHGEF12,ZFR,DDX23,ATP6V1D,SEC23IP,L3MBTL3,E2F1,TAF12,PGAM1,HIPK3,IFI16,NUP188,MAX,PNISR,PDCD6IP,GXYLT1,ADAM10,CXXC1,AP3M2,CUL1,NANS,GYG1,UBE2I,SLC25A37,ANKRD26,NOL11,CISD2,TAF5L,SLC26A2,SRP72,SGCE,OSBP2,KLF10,NSUN2,CLNS1A,EIF3A,IWS1,ZMYM3,MAP3K4,TPP2,MAP4,PTPDC1,NMD3,PTOV1,PRPF38B,RECQL,C9orf78,DNAJC5,C16orf87,PRKAA1,ANKH,RRM1,DLGAP4,ACAP1,TATDN3,B4GALT1,PXMP2,FAM136A,PSEN1,PDXDC1,VPS25,NPLOC4,CNOT3,SPAG5,C12orf10,RPN1,CEP104,KLHL5,ZNRF2,MSH2,DAPK1,PIGG,TPST1,FBXL7,OSTF1,FAM171A1,SYTL3,FDFT1,GCC2,PRIM2,ELL2,MFNG,GORASP2,EXOSC9,CAPZA2,ARID1A,FXR1,GOSR1,MAP2K2,CCT8,MTR,TWISTNB,XRCC5,CAT,SLCO4A1,HSPBP1,TTC13,GOLGA2,MED15,USP32,FAM83D,APPL2,CABIN1,SAMD8,SMPD4,GPI,NUDT3,CDKN2A,ZNF511,CYTIP,TP53RK,ATXN3,RAB11B,RAF1,KIAA0232,POMP,BCL2L1,CD320,EPM2A,NUDT19,DECR1,CCNA2,MTMR4,ADCY9,MRPS27,TTC3,RNASEH2A,AQR,CDK12,ANKLE2,BRD4,CDC123,ELP4,LRRC8A,PKMYT1,ERC1,EML4,TRIM28,SUPT16H,ZNF282,DDOST,DSN1,DGCR8,SAFB,LMBR1,ATF6,NCLN,EYA2,PRPF4B,ADAM23,NDUFS1,B4GALT5,MECP2,MANBA,TKT,CBLL1,SECISBP2,POFUT1,HMG20A,FAM8A1,HEATR5B,SLC25A36,WWP2,CCNK,FUT8,PTPN11,BTF3L4,MRPL54,RPL19,CNN2,MTX2,JMJD4,FBXO9,PACS1,KCNQ1,OTUD3,KIF11,MACF1,SMAP2,MYO1F,TMEM127,DDX5,WDR91,TAF6,DEF6,POLA2,UBL3,LYRM4,GPR132,HMGXB3,PTP4A3,ABCB10,MAP1LC3B,MRPL19,SF3B2,DST,SIVA1,JAZF1,HADHB,RPF2,GPATCH1,SLC35C2,CARM1,SRPK2,WDR41,LARS,ZCCHC10,SNRNP200,CCDC138,VHL,LRBA,SREK1,KMT2C,PRPSAP1,ASF1B,MAN2A2,HSPB11,EIF4ENIF1,U2SURP,MIA2,BAZ1B,ZNF268,STK11,CHEK2,CLU,ZSWIM3,CHPT1,MRPL13,TSTD2,ATP6V0E1,DCAF5,CAPN1,UBE2D3,PPP1R12A,ZCCHC8,C19orf25,RGS2,QSOX2,NUP205,PRPF18,LYAR,DTL,MED10,ZRANB1,SLC12A2,ATP6V0D1,CSNK1G3,TRAFD1,NUDT4,SUGP2,EIF2A,DAPK3,ARHGAP15,EVC2,MASTL,UAP1,FN3KRP,SLC16A1,YWHAZ,SNRNP70,EHD4,APOL2,ADNP2,FEZ2,MDH2,PMS2,UCK2,SMARCA4,ORC1,MXD1,RRN3,IARS,NVL,EXOSC1,CS,CLTB,POU2AF1,UBQLN4,PGGT1B,PCGF6,SMU1,GLO1,OGDH,CADM1,BICD2,HERPUD2,TOLLIP,MBD3,PDHX,PON2,SURF4,HNRNPR,STAT6,ARNTL,FKBP5,TMEM101,CCDC125,MAPK1,ABCA1,PDCD2L,DNAJC2,GCLM,TRIP12,SHPRH,SCYL1,NUP54,VPS45,CHIC2,PAWR,DCUN1D4,GFM2,PIP4K2A,XPR1,FASTKD3,FGFR3,KLHL20,PPIG,RRBP1,H2AFY,ARHGEF2,LDLRAD3,ERI3,STAT3,SLC35A1,MYO5A,TXNL1,B3GALT6,TMEM39A,PSPC1,HELB,SCFD2,RCOR1,COG1,PRMT2,NDRG3,CDK11A,LEMD2,SERF1B,ELMO1,ZC3H7B,MEGF9,ZMIZ1,PLOD3,HRAS,RAB3IL1,ZSWIM6,CCDC93,RAB14,ADD1,KDM4A,PIGQ,DHX8,PPP1R16B,CALM2,CDK5,NEK6,NSRP1,RABGAP1L,SRSF4,PDS5B,NUP153,PCBP2,PGAP2,PLK3,MRPL43,PLEKHM3,PPFIA3,ICMT,PWWP2B,WDR11,AXIN1,LIMK1,ATE1,FBXL3,E2F2,LONP2,PFKP,DDX42,NDUFV2,CERK,TOP2B,SLC4A2,EZH1,TMED3,ITGB5,LMNA,RAVER2,GNS,DDX56,EIF2S2,INTS7,PHF14,ZNF326,FOXN2,CARS2,UBE2QL1,RB1CC1,DHX29,PGS1,MAN1B1,TEX10,MYBL2,UHRF1BP1,CBFA2T2,ABCF1,PTPRF,SCARB2,OSBPL11,POLR2J,DUSP3,SETD3,CNOT6,NDE1,HEXA,RNF139,SNX14,EGLN1,PPP1R37,ANKRD27,SARNP,ABCA3,TRERF1,UBR2,ACTR3,WDTC1,MYH9,ZNF267,PRKACA,SAFB2,APP,ANKIB1,STAM,TMEM161B,CLUAP1,PRKD3,ATP2A2,UTP18,GRSF1,ZCCHC2,DDA1,ANKRD13C,ATF2,GCC1,TMEM9,RNF169,DCTN1,ATP6V1G1,ADCY7,SHOC2,MAP4K4,ATP6V0A1,NUSAP1,CDCA2,DDX17,CHCHD3,CDC16,HIPK2,WDR7,MBOAT1,PDXK,LRP8,LRCH1,ZNF786,TMBIM4,SESTD1,TRAK1,GMCL1,JMJD6,AKT1S1,ZNF92,KRI1,FBXO3,CAPN2,ADD3,NDUFB4,DCP1A,TTLL12,SGCB,IMPA2,NUDC,PDPK1,PPP3CA,TNFAIP3,POLK,GALC,ZNF512,KIAA0930,ZP3,PDE3B,RPA1,ZNF180,ZNF862,KIF18A,CCDC6,TATDN2,MAPK6,CAPN7,LRPPRC,PML,LY75,RGL1,WDR76,PSAP,USF2,IGBP1,ANAPC4,FAF1,SNAPIN,THOC1,AGRN,GNPDA1,MCCC1,CSNK2A1,SEC16A,GIT2,ATPAF1,LIN9,DLG5,ABL2,TRMU,ETV6,XRCC2,PPCDC,ZFYVE27,MCMBP,MRPL32,CCAR1,CDC37,ABCC5,METTL1,HARS,TLK1,GMFB,EZR,LRP5,ANLN,RHEB,EPB41,OPTN,QRSL1,PIEZO1,GLCCI1,NUDT11,CTCF,RACGAP1,PPP3CB,DOCK11,CRLF3,RB1,VASP,VMP1,SLC27A4,MDFIC,MAML1,TMEM8A,ALDH18A1,TRAPPC9,AACS,MEMO1,UTP15,EIF2AK1,KRAS,ARPC1A,GOLGA4,SYNCRIP,CDC27,PRPS2,TBPL1,PRMT7,KCTD7,UGP2,FOXM1,MRPL39,XAB2,COPE,DUSP22,GGPS1,RAD23A,PDK2,STRBP,MRPL34,CORO1A,MINPP1,METTL9,DVL2,SLC39A9,CLPTM1,PSMA8,COQ10B,CPOX,SLC26A6,CYP20A1,NFATC2,PRPF3,KDM1B,TXNL4A,RPSA,DNAJC10,ZNF700,SCAP,CLK3,TIMM17A,CEP55,DNAJC17,NCOA1,USP53,ZC3HC1,INTS2,CTDP1,GOLIM4,MIF4GD,RRP15,DAP,ARID5A,SMC6,SUMF1,GGA2,AP3S1,CSNK1A1,BZW2,TFRC,WRNIP1,PTPN2,NDUFV1,SLC1A4,CWC27,TMA7,ABCD1,DDX31,PTGES3,CAMK2G,RPAP3,ZMYM5,PPWD1,RHOT2,CHCHD6,TPD52L2,KPNA4,GOLGA7,BIRC5,TWSG1,SNAP29,CDCA7L,GLG1,PGRMC1,FAM126A,PKD2,RPS6KC1,NDUFB6,TMEM41B,YTHDF3,PLXNA1,NHLRC3,IKBIP,COMMD6,ELMOD2,ABHD14A,KIFC1,ASAP2,SNUPN,CYB5RL,PARPBP,CDC25B,PLCL2,DNMT1,NOL12,AKT2,PBK,NOL8,DDX20,AURKB,GALNT7,SLC17A5,CCNF,SLC25A5,ZFAND5,STT3A,TMED10,PTER,EIF2D,ITGB1,UQCRH,RTN3,ZNF598,DDX58,WSB2,HSPH1,MUT,KIF23,NDUFA4,SLC35B1,PMF1,NOTCH2,NDUFS4,FKBP1A,NDUFAF6,RNF121,HDAC7,BDH1,PIKFYVE,RNF135,GNAI2,LPCAT1,TMED2,MORC3,PIP4K2C,KCTD20,PLEC,ADSS,EPRS,NSF,DCK,ACLY,LPCAT4,VCPIP1,YY1,PPP6R2,MAP3K5,RNF14,CDK2,CABLES1,NRBP1,ZC3HAV1,DNMT3A,RWDD1,SUZ12,RPS6KA1,SF3B1,URB2,GPR89A,EIF3D,OLA1,SDHA,PHC2,APLP2,ZNF75D,SHC1,KDM2A,UCHL5,TALDO1,NAA35,GPX4,MAPRE2,MKLN1,CUL3,SLBP,KIAA1586,GALK2,CDC23,SHCBP1,POLG2,H2AFV,AP4E1,DHX57,PRDM11,NSA2,VEZF1,HSPA4,JAK1,PPP2R5A,GOLGA8A,SEL1L,STAT1,KLHDC4,PDCD11,POLQ,NCOR2,PKP4,C1orf112,TCF3,MRI1,BRAP,SLC25A12,AGPAT3,SPR,RAB11A,REEP5,FOXO3,GTF2F1,TMCC3,RBM17,PTEN,CRAT,COPS7B,SLC38A10,UPF2,IFT46,UBE2M,PACS2,NCOA2,ZFP64,NEK7,DENND1B,DENND4C,PARP4,LRRC1,RHOT1,MARK2,GNA12,FBXO21,NUCB1,C1orf131,HGS,PFDN4,PRDX3,SLC38A7,TFDP1,STX18,KHSRP,BRWD3,BYSL,ESYT2,MIB2,NPHP4,UBE2E2,PLXNC1,ST13,UBN1,DCAF15,NF1,DNAJC24,SLC29A1,TAF6L,USP48,MAPK14,EDC3,ZNF804A,THADA,AP3S2,ZNHIT6,IMPAD1,ATG3,DPYSL2,RCSD1,PHTF1,PPP1R12C,AKR1B1,NDUFB9,RP2,NFU1,TTC4,TECR,OGG1,TRIM14,COPS8,FYTTD1,TDP1,TRIM8,FOPNL,SLC16A7,STK17B,DHX15,PAF1,GEMIN5,UBTF,CXXC4,SPATA2,ATXN2L,IARS2,GALNT10,PSMC1,SLC12A7,TBC1D12,PIGN,MED13L,TIA1,MEF2A,EPHX2,PITHD1,RHBDD1,ZNF449,CAPZA1,YBX1,KIFAP3,BCL2,GLTP,KNTC1,UBE3C,ALDH9A1,VOPP1,SEPT7,C22orf46,GNAS,TSC1,RBM25,EXOC4,KIAA1328,PITPNA,PTDSS1,MZT2B,PDSS2,SMARCD1,MMACHC,IMMT,ASH1L,MPHOSPH8,WDYHV1,TWF2,CHD1,PAIP1,MEAF6,CCDC50,AKAP8,PARL,RPN2,APOOL,F2R,SCYL3,ACSL5,FAM172A,ZNF500,PSMB7,NLN,BTBD1,RAD54B,TAB2,TULP3,WDR59,SCARB1,GAS2,AKNA,SMURF1,PPP2R2D,TSPAN5,KIF3B,GOLPH3L,MRPL42,CASP6,EYA1,SRGN,KLF13,HDDC2,MAN1A1,CTNNBL1,BRD7,TTC17,GINS1,SAMD4B,ZDHHC18,CSNK1G2,ADAM17,NASP,ASPM,PRKAR1B,MEN1,ZNF407,SYMPK,SNRPA,MAPK3,MFN2,ATAD2,OSBPL8,PREPL |
| 1.992e-03 | -6.22 | GO_UNFOLDED_PROTEIN_BINDING | MSigDB lists | GO_UNFOLDED_PROTEIN_BINDING | 92 | 25 | 17377 | 2626 |
CCT2,PPIB,TOMM20,ST13,DNAJB2,DNAJA1,SYVN1,DNAJB1,CCT8,HSPA1B,CHAF1A,PFDN5,PFDN4,PDRG1,SCAP,SIL1,RP2,RUVBL2,NAP1L4,PTGES3,LMAN1,CLN3,HTRA2,SRSF10,CDC37 |
| 1.997e-03 | -6.22 | retina | COSMIC cancer mutations | retina | 29 | 11 | 17385 | 2587 |
RB1,EWSR1,LHX8,NRAS,PTEN,SF3B1,KRAS,DMWD,H3F3A,HRAS,STOML2 |
| 1.997e-03 | -6.22 | adnexal_tumour | COSMIC cancer mutations | adnexal_tumour | 25 | 10 | 17385 | 2587 |
FGFR3,EWSR1,CYLD,NRAS,PTEN,SF3B1,MSH2,KRAS,HRAS,CDKN2A |
| 2.000e-03 | -6.21 | Junb (jun B proto-oncogene) | protein interactions | 16477 | 100 | 28 | 17029 | 2761 |
GOLIM4,BRD4,AGGF1,DEPDC1,CHERP,KAT7,TRIR,SF3B1,CIRBP,ADCK5,HDGFL2,BIRC2,SF3B2,DDX23,RBM17,HNRNPA2B1,EPRS,DNAJC8,SYNCRIP,NSRP1,MFAP1,MED15,U2SURP,IMPDH1,TNPO3,RPN2,ECD,CCAR1 |
| 2.007e-03 | -6.21 | RPS27 (ribosomal protein S27) | protein interactions | 6232 | 138 | 36 | 17029 | 2761 |
RPS15,RPS2,RPL35,CYLD,RPLP2,VHL,EIF3D,RPS10,RPL6,RPL38,RPL8,CUL3,RPL15,CUL1,RPS24,AURKB,BRCA1,SND1,MCM2,RPL27A,RPS9,RPSA,PNO1,RPL11,RPL23A,CAND1,MDM2,PTEN,RPS14,ACTB,FUS,FAU,CDK2,RPS26,BYSL,CDC37 |
| 2.007e-03 | -6.21 | CALR (calreticulin) | protein interactions | 811 | 138 | 36 | 17029 | 2761 |
EWSR1,PRKCSH,HLA-E,SUZ12,SLC2A1,TAP1,TKT,ATP5F1B,PRKACA,APP,CDC73,HLA-A,EEF2K,PCNA,ARPC5,HUWE1,PPME1,UPF2,PTGES3,ATF2,WDR1,NSUN2,EZR,KRAS,MCM2,ARPC1A,MATR3,SH3GLB1,RPA1,EPB41,HLA-B,TPD52L2,PFDN5,MAPK6,H2AFX,CDK2 |
| 2.023e-03 | -6.20 | Kif23 (kinesin family member 23) | protein interactions | 71819 | 13 | 7 | 17029 | 2761 |
KIF23,RACGAP1,PAWR,SHCBP1,PHB2,CCAR1,MICAL3 |
| 2.023e-03 | -6.20 | Cdk2ap1 (CDK2 (cyclin-dependent kinase 2)-associated protein 1) | protein interactions | 13445 | 13 | 7 | 17029 | 2761 |
RBBP4,CHD3,MBD3,MTA1,MTA2,MBD2,HDAC2 |
| 2.023e-03 | -6.20 | XAF1 (XIAP associated factor 1) | protein interactions | 54739 | 13 | 7 | 17029 | 2761 |
BIRC3,BIRC2,HIPK2,APP,RNF114,XIAP,SIAH2 |
| 2.023e-03 | -6.20 | DHODH (dihydroorotate dehydrogenase (quinone)) | protein interactions | 1723 | 13 | 7 | 17029 | 2761 |
NDUFS8,CYC1,OGDH,TMED10,SDHA,HNRNPM,ILF3 |
| 2.023e-03 | -6.20 | TCF19 (transcription factor 19) | protein interactions | 6941 | 13 | 7 | 17029 | 2761 |
LIN9,LZTR1,GOLGA2,MBD3,MTA1,MTA2,APP |
| 2.023e-03 | -6.20 | DHX58 (DExH-box helicase 58) | protein interactions | 79132 | 13 | 7 | 17029 | 2761 |
AP2B1,CDKN2AIP,NKRF,STAU1,APP,USP21,AGO2 |
| 2.023e-03 | -6.20 | SDHC (succinate dehydrogenase complex subunit C) | protein interactions | 6391 | 13 | 7 | 17029 | 2761 |
IMPDH1,SDHB,UNK,MDM2,SDHA,POC5,DCTN1 |
| 2.023e-03 | -6.20 | ABHD11 (abhydrolase domain containing 11) | protein interactions | 83451 | 13 | 7 | 17029 | 2761 |
BOLA3,BOLA1,ABHD11,ACAD8,APP,ECH1,FAS |
| 2.024e-03 | -6.20 | TPCN2 (two pore segment channel 2) | protein interactions | 219931 | 51 | 17 | 17029 | 2761 |
ZDHHC18,ANKRD27,CLCN3,ACP2,B4GALT5,CERK,AP3S1,APPL1,CD320,EBP,PI4K2A,WDR11,WDR44,USP32,EHD4,ARRB2,CSNK1G3 |
| 2.024e-03 | -6.20 | MRPL3 (mitochondrial ribosomal protein L3) | protein interactions | 11222 | 51 | 17 | 17029 | 2761 |
PPAN,RPS15,MRPL9,CYLD,MRPL42,MRPL39,MRPL12,TUFM,MRPL19,APP,CAND1,MRPL50,TIMM13,MRPL55,RPS14,MRPS27,MRPL13 |
| 2.024e-03 | -6.20 | RRBP1 (ribosome binding protein 1) | protein interactions | 6238 | 51 | 17 | 17029 | 2761 |
PPIF,CHMP2A,EWSR1,RBM8A,RPL38,ILF3,CUL3,NDUFA7,KIF5B,RAB8A,PQBP1,BUD31,RBMS1,TARDBP,EEF1D,HNRNPM,SMNDC1 |
| 2.024e-03 | -6.20 | outer membrane | cellular component | GO:0019867 | 204 | 46 | 18223 | 2701 |
TOMM20,MTX3,PHB2,RAF1,ANKH,TMEM109,STARD7,LETMD1,BCL2L1,SNN,SLC25A44,PSEN1,FOXO3,MIEF1,MOAP1,TIGAR,SLC44A1,HADHB,BCL2,CISD2,MAVS,ATF2,MTX2,TRIM14,ACSL5,BAK1,SIGMAR1,ACSL3,VDAC2,MCL1,MTX1,NUTF2,RHOT1,VDAC1,TOMM40,RHOT2,SH3GLB1,CYB5A,MFN2,AKAP1,ANKZF1,ATP5MC3,RPS27A,TOMM6,LRPPRC,NIPSNAP2 |
| 2.026e-03 | -6.20 | GSE16385_MONOCYTE_VS_12H_IFNG_TNF_TREATED_MACROPHAGE_UP | MSigDB lists | GSE16385_MONOCYTE_VS_12H_IFNG_TNF_TREATED_MACROPHAGE_UP | 179 | 42 | 17377 | 2626 |
CHMP2A,NSMCE4A,MAPRE1,PARP12,RPLP2,TM9SF4,MED13L,KLF13,BZW2,APP,PABPC4,COPB2,DTL,RPA2,STARD9,PSMD1,ATP2A2,YBX1,CYC1,GEMIN4,CFL1,RBM15B,EIF5A,DDX28,RHOA,SEPT9,EID1,MTA2,MRS2,MCL1,LY6E,SOX4,SERP1,EPB41,RPL36,L3MBTL3,ZNF689,SAFB,ITGB1,SLC16A1,MRFAP1L1,MRPL13 |
| 2.026e-03 | -6.20 | GSE411_UNSTIM_VS_400MIN_IL6_STIM_MACROPHAGE_UP | MSigDB lists | GSE411_UNSTIM_VS_400MIN_IL6_STIM_MACROPHAGE_UP | 179 | 42 | 17377 | 2626 |
SLC12A7,SRM,MBD1,MAGEH1,CYLD,MRPS2,TOR3A,TRMT6,MOGS,KLF13,ARFIP2,C2orf49,C19orf48,APH1B,STAM,COPG2,HMG20A,CCDC28A,ZBTB45,EXOSC7,METTL14,RPAP1,PARL,COPS7B,TARDBP,SLC35A1,ABCC5,METTL1,MIOS,EID1,TUBGCP5,GLO1,DTWD1,ZNF862,CAMKMT,LMBR1,DDX5,MAP3K5,TFDP2,CHPT1,ACSF2,ANAPC4 |
| 2.026e-03 | -6.20 | GSE42724_MEMORY_VS_B1_BCELL_UP | MSigDB lists | GSE42724_MEMORY_VS_B1_BCELL_UP | 179 | 42 | 17377 | 2626 |
SEPHS2,C1orf74,PRKAB1,SCOC,CXXC1,TMEM41B,PMS2,VTI1A,RCOR3,TMEM165,NPLOC4,PAIP2,MOAP1,SEC11A,RB1,C1GALT1,RIMS3,RNASEK,AKAP8,LTN1,FOXN2,PHKG2,OGG1,CAMK2G,ELOF1,PBXIP1,UTP15,CIRBP,MAP7D1,EDEM2,PEF1,DAPK3,BTBD1,KIF2A,HGS,PDRG1,GPS2,C1orf109,APPL2,C4orf46,NUP62,BRD9 |
| 2.029e-03 | -6.20 | GSE40274_CTRL_VS_HELIOS_TRANSDUCED_ACTIVATED_CD4_TCELL_DN | MSigDB lists | GSE40274_CTRL_VS_HELIOS_TRANSDUCED_ACTIVATED_CD4_TCELL_DN | 158 | 38 | 17377 | 2626 |
MIF,SRM,IER2,HSPH1,PHB2,ADO,ADPGK,SLC20A1,IL21R,ANKIB1,CHD1,PIP5K1C,SRXN1,LYAR,HOMER1,PSMD1,AHCTF1,RPF2,POLR1B,CNOT6L,TIMM50,PLK3,NXT1,RBX1,TBRG4,EAF2,TOMM40,ISG15,CAND1,ATP1A1,IDE,PLAA,ETS2,TBL3,PTPDC1,CSNK1D,IPO4,VPS29 |
| 2.045e-03 | -6.19 | GO_TRNA_PROCESSING | MSigDB lists | GO_TRNA_PROCESSING | 102 | 27 | 17377 | 2626 |
METTL1,CTU2,RPP25,KARS,TP53RK,NSUN2,TRMT6,TYW1,METTL2A,LAGE3,C2orf49,GTPBP3,DUS4L,DUS3L,LSM6,GRSF1,WDR4,TRMU,TYW5,UBA5,POP7,FTSJ1,OSGEPL1,FBL,CPSF4,TSEN15,TYW1B |
| 2.058e-03 | -6.19 | MAPT (microtubule associated protein tau) | protein interactions | 4137 | 119 | 32 | 17029 | 2761 |
STAU1,EWSR1,GNPNAT1,AATF,CASP6,RPS6KA1,CDCA8,CSNK2A1,CSNK1A1,PRKACA,PSEN1,GAR1,MARK2,APP,TFEB,CDK5,PPP2CA,CAPN2,SMAD2,HSPA4,PPP2R5A,SYNCRIP,PIN1,DNAAF2,OGT,YWHAZ,ACTB,PPP5C,CDK2,CSNK1D,TUBB,DCTN1 |
| 2.061e-03 | -6.18 | GNF2_DDX5 | MSigDB lists | GNF2_DDX5 | 59 | 18 | 17377 | 2626 |
YTHDC1,MBD1,CSNK1G2,HECA,SF3B1,SRSF6,NACA,ADPGK,SRSF5,STX16,CHD1,BIRC2,PAPOLA,MBD4,STK38,DDX5,H3F3A,ADCY7 |
| 2.062e-03 | -6.18 | HNRNPCL1 (heterogeneous nuclear ribonucleoprotein C-like 1) | protein interactions | 343069 | 27 | 11 | 17029 | 2761 |
RPA2,MCM5,HNRNPUL2,CUL3,SREK1,CUL1,TFG,NKAPD1,RPA1,SRPK2,CAND1 |
| 2.062e-03 | -6.18 | MRPL57 (mitochondrial ribosomal protein L57) | protein interactions | 78988 | 27 | 11 | 17029 | 2761 |
MRPL50,NRF1,DDX28,EWSR1,MRPL42,MRPL39,KBTBD7,MRPL12,XPNPEP3,MRPL19,MRPL32 |
| 2.062e-03 | -6.18 | KLK11 (kallikrein related peptidase 11) | protein interactions | 11012 | 27 | 11 | 17029 | 2761 |
RB1,VMP1,TIMM29,MANBA,TBL3,CHD1L,CBWD1,AP3S1,CHPT1,KIAA1147,SPSB3 |
| 2.062e-03 | -6.18 | MAPK1IP1L (mitogen-activated protein kinase 1 interacting protein 1 like) | protein interactions | 93487 | 27 | 11 | 17029 | 2761 |
MTMR3,HGS,EWSR1,PDCD6,CEP55,PTPN7,SS18L1,PTPDC1,CDC25B,UBE2I,TFG |
| 2.062e-03 | -6.18 | POLR2K (RNA polymerase II subunit K) | protein interactions | 5440 | 27 | 11 | 17029 | 2761 |
POLR2I,MED10,POLR2G,POLR2J,POLR2K,ELOA,POLR2D,BRCA1,PSMB9,APP,POLR2A |
| 2.062e-03 | -6.18 | Pfdn2 (prefoldin 2) | protein interactions | 18637 | 27 | 11 | 17029 | 2761 |
RPAP3,PFDN5,SCAMP3,TIMM23,PDRG1,PFDN4,URB2,COPS7B,RUVBL2,CCT8,POLR2A |
| 2.062e-03 | -6.18 | AKR1A1 (aldo-keto reductase family 1 member A1) | protein interactions | 10327 | 27 | 11 | 17029 | 2761 |
TERF2IP,PDCD6,MEMO1,TKT,NANS,GPI,PKM,TALDO1,PCBP1,TERF1,CFL1 |
| 2.062e-03 | -6.18 | PRR3 (proline rich 3) | protein interactions | 80742 | 27 | 11 | 17029 | 2761 |
CRKL,NIFK,CCDC57,RPS2,HNRNPR,CENPJ,RBMX,LAMTOR3,KIF11,MATR3,FANCI |
| 2.062e-03 | -6.18 | RIOK2 (RIO kinase 2) | protein interactions | 55781 | 27 | 11 | 17029 | 2761 |
EIF3L,EWSR1,RPRD1A,TSTA3,CENPJ,MRPS27,CSNK2A1,BEND3,APP,EIF3A,HP1BP3 |
| 2.063e-03 | -6.18 | vesicle localization | biological process | GO:0051648 | 237 | 53 | 17256 | 2622 |
KIF3B,DNAJC5,RAB11B,GORASP1,DCTN2,TRAK1,AP3M2,KIF23,AP3S1,SEC16A,PSEN1,RAB11A,PIP5K1C,KIF5B,ANKRD28,CDK5,CD59,AP3S2,RIMS3,SEC24C,PPP6C,DNM2,KIFAP3,LMAN1,TFG,SYTL3,PPP6R1,MYO5A,TMED2,PREB,DCTN1,USO1,TRAPPC9,CUL3,MCFD2,RAB1A,PEF1,SEC31A,SEC23IP,PDCD6,GOLGA2,NSF,TMED10,SNAP29,SNAP23,EXOC4,NDE1,PPP6R3,CLN3,UNC13C,CSNK1D,STARD3NL,SNAPIN |
| 2.070e-03 | -6.18 | TOPORS (TOP1 binding arginine/serine rich protein) | protein interactions | 10210 | 64 | 20 | 17029 | 2761 |
UBE2D3,PLK1,ZNF786,NIFK,SF3B1,SUMO2,HABP4,TOPORS,RANGAP1,UBE2I,SAFB2,TRIM28,DHX15,EPM2A,CLK3,PML,H2AFX,RBBP4,PSMC1,HNRNPM |
| 2.070e-03 | -6.18 | HIST1H2AB (histone cluster 1 H2A family member b) | protein interactions | 8335 | 64 | 20 | 17029 | 2761 |
COX15,CUL1,BRCA1,MCM2,VDAC1,SDHA,PARK7,MAPK3,SUPT16H,CAND1,HNRNPA2B1,PTEN,RPL17,MCM5,WDR4,H2AFY,EHD4,MAPK1,CDK2,CBX4 |
| 2.070e-03 | -6.18 | RPS29 (ribosomal protein S29) | protein interactions | 6235 | 64 | 20 | 17029 | 2761 |
RPS15,RPS2,CYLD,RPS10,RPL8,RPS24,KRAS,EIF2A,MCM2,EIF1B,STYXL1,EXT2,RPS9,RPSA,DDX56,RPS14,RPL19,FAU,RPS26,SMARCD1 |
| 2.070e-03 | -6.18 | ALDH3A2 (aldehyde dehydrogenase 3 family member A2) | protein interactions | 224 | 64 | 20 | 17029 | 2761 |
TSC2,C1orf112,TMEM216,CUL3,DDX20,CAPZA2,CIP2A,LMNA,NCDN,CAND1,EVC2,HUWE1,THADA,INTS1,INTS12,LTN1,GEMIN4,ATP6V1C1,PPP6R2,PPP6R1 |
| 2.070e-03 | -6.18 | DIS3 (DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease) | protein interactions | 22894 | 64 | 20 | 17029 | 2761 |
EXOSC6,SARNP,WDR1,BABAM1,CUL3,EXOSC9,SEPT7,SCYL2,SH3GLB1,CDK5,GNAS,RBM23,SUB1,EXOSC7,SSBP3,EXOSC1,YJU2,SEPT11,PPP5C,NMD3 |
| 2.076e-03 | -6.18 | Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models | REACTOME pathways | R-HSA-8862803 | 23 | 10 | 10287 | 1696 |
CDK5,CAPN2,GOLGA2,CAST,CDC25B,FOXO3,APP,LMNA,PRDX1,CAPN1 |
| 2.076e-03 | -6.18 | Neurodegenerative Diseases | REACTOME pathways | R-HSA-8863678 | 23 | 10 | 10287 | 1696 |
CDK5,CAPN2,GOLGA2,CAST,CDC25B,FOXO3,APP,LMNA,PRDX1,CAPN1 |
| 2.077e-03 | -6.18 | GO_LYTIC_VACUOLE_ORGANIZATION | MSigDB lists | GO_LYTIC_VACUOLE_ORGANIZATION | 50 | 16 | 17377 | 2626 |
NAGPA,RAB14,ACP2,PPT1,RAB7A,HEXB,ARF1,BECN1,TMEM165,TFEB,NAGLU,ATP6V0C,CORO1A,CLN3,CLN6,ABCA1 |
| 2.077e-03 | -6.18 | FLECHNER_PBL_KIDNEY_TRANSPLANT_REJECTED_VS_OK_DN | MSigDB lists | FLECHNER_PBL_KIDNEY_TRANSPLANT_REJECTED_VS_OK_DN | 50 | 16 | 17377 | 2626 |
RPS2,CTCF,BICD2,MAPK14,TXNL4A,SAFB2,CHAF1A,RPL11,EIF3K,MAN2A2,SYNCRIP,STK38,ITGB1,CDKN1B,SRSF3,PCBP2 |
| 2.077e-03 | -6.18 | GO_LYSOSOME_ORGANIZATION | MSigDB lists | GO_LYSOSOME_ORGANIZATION | 50 | 16 | 17377 | 2626 |
NAGPA,RAB14,ACP2,PPT1,RAB7A,HEXB,ARF1,BECN1,TMEM165,TFEB,NAGLU,ATP6V0C,CORO1A,CLN3,CLN6,ABCA1 |
| 2.077e-03 | -6.18 | CHAUHAN_RESPONSE_TO_METHOXYESTRADIOL_UP | MSigDB lists | CHAUHAN_RESPONSE_TO_METHOXYESTRADIOL_UP | 50 | 16 | 17377 | 2626 |
SRM,SRSF6,PTTG1,CIRBP,DNAJA1,SNRPD3,CCNB1,ITGB5,HMGN2,PSMD1,AHSA1,PPIL2,TARDBP,RBM3,CHMP7,UBE2M |
| 2.077e-03 | -6.18 | guanyl nucleotide binding | molecular function | GO:0019001 | 388 | 81 | 17224 | 2647 |
RHOG,RAB14,RAB11B,RAC1,OLA1,TPX2,RRAGC,GLUD1,EFL1,MIEF1,RAB21,RAB8A,RAP1A,CDC42,SAR1A,RALB,RAB35,RAB4A,DNM2,UPRT,SEPT11,SUCLG2,RP2,EIF5,ARL5A,RHOBTB3,NRAS,SEPT9,CGAS,RAB7A,RAB1A,ARL5B,RAB5B,RAB22A,LSG1,RAB2B,ARF4,RHEB,DAP3,SEPT1,RAB24,GUCY1B1,TUBB,RHEBL1,ANXA6,RHOC,GSPT2,RAB23,ARFIP2,RAB6A,ARF1,IFT27,RAB11A,GFM2,RTKN,GTPBP3,ARF5,EFTUD2,DAPK1,GNAI2,RHOA,NOA1,TUFM,GTPBP4,SEPT8,BMS1,KRAS,RIT1,RHOT1,SEPT7,RHOT2,GUF1,RHOB,MFN2,GNAS,ADSS,GNA12,RAB18,PRPS2,EHD4,HRAS |
| 2.081e-03 | -6.17 | CONCANNON_APOPTOSIS_BY_EPOXOMICIN_DN | MSigDB lists | CONCANNON_APOPTOSIS_BY_EPOXOMICIN_DN | 153 | 37 | 17377 | 2626 |
NDUFB6,PTTG1,TMX4,LAGE3,AGPAT1,KIF23,HMGN3,STMN1,ABHD14A,MFSD10,TFRC,KIFC1,CCNA2,NDUFA2,SPTSSA,GM2A,PLK1,POLR2L,EID1,LDHA,MKI67,EXOSC9,AURKB,CADM1,NDUFB1,H2AFV,CYB5A,AKAP1,ACYP1,BIRC5,ELMO1,DBI,HMGB2,SNRPG,UBE2C,ESPL1,PFKP |
| 2.084e-03 | -6.17 | HTR2C (5-hydroxytryptamine receptor 2C) | protein interactions | 3358 | 91 | 26 | 17029 | 2761 |
ACP2,BTAF1,GPR89A,MRS2,C19orf25,TM9SF3,UBE2Q1,LRRC8A,MTX1,TMEM147,ATP5F1B,XPO7,NCAPG,PDXDC1,SFXN5,GNB2,CIP2A,CAND1,ITPRIPL1,CERS6,PDS5B,TNPO3,TNPO2,KNTC1,ARRB2,ECPAS |
| 2.091e-03 | -6.17 | GSE25123_IL4_VS_IL4_AND_ROSIGLITAZONE_STIM_MACROPHAGE_DAY10_DN | MSigDB lists | GSE25123_IL4_VS_IL4_AND_ROSIGLITAZONE_STIM_MACROPHAGE_DAY10_DN | 174 | 41 | 17377 | 2626 |
NDUFA5,PRPF38B,PNISR,MTX3,EYA1,STRN4,HMGN3,ADPGK,MXD4,CCNL2,ANKRD23,FAM8A1,MYL6B,RSAD1,ANKRD39,WDR48,SLC25A36,NRF1,NDUFA2,RINL,DAPK1,TTC3,SLC38A10,ZRANB1,FBXL19,DCTN1,PRPF19,AMPD2,TSHZ1,YTHDC1,KIAA0040,SUGP2,ZMYM3,SOCS7,SERF2,UBXN2B,ZNF436,DVL1,SNRPG,CSNK1D,PRPF4B |
| 2.091e-03 | -6.17 | GSE17974_CTRL_VS_ACT_IL4_AND_ANTI_IL12_4H_CD4_TCELL_DN | MSigDB lists | GSE17974_CTRL_VS_ACT_IL4_AND_ANTI_IL12_4H_CD4_TCELL_DN | 174 | 41 | 17377 | 2626 |
SRM,PIGM,IMMT,PHF23,URB2,B4GALT5,ADO,SLC29A1,BRIX1,RAB11A,PNO1,IRF4,HOMER1,RAP1A,LPIN2,PRADC1,CLN6,FTSJ3,TIMM50,MLEC,TMEM126B,MRPL12,TMEM147,GAR1,FADD,BBS12,PRDX1,GEMIN5,TIMM13,ORMDL2,PSMD8,DNAJC17,SMG9,RUVBL2,CENPBD1,NAA20,RRS1,PDCD2L,GPATCH4,BYSL,NIPA1 |
| 2.091e-03 | -6.17 | GSE29615_CTRL_VS_DAY3_LAIV_IFLU_VACCINE_PBMC_UP | MSigDB lists | GSE29615_CTRL_VS_DAY3_LAIV_IFLU_VACCINE_PBMC_UP | 174 | 41 | 17377 | 2626 |
MZT1,FAM53C,RAE1,DHX9,YTHDF3,IP6K2,BRIX1,FAM8A1,CHD1,CCDC28A,DNAJB9,DTL,DDA1,PRC1,DCP1A,ZRANB1,TFG,ZNF770,STRAP,FYTTD1,ZDHHC18,DPM1,COQ10B,MTMR6,BCLAF1,TOPORS,PNPLA8,CHMP2B,RAB1A,DPYSL3,PI4K2A,PPP2CA,MBIP,TXNDC16,MAPK6,PML,TBPL1,FBXL3,ZNF598,COIL,SLC25A39 |
| 2.093e-03 | -6.17 | Height(PMID:20881960) | GWAS genes | Height(PMID:20881960) | 109 | 25 | 2388 | 307 |
CTU2,DMAC2,SLBP,KCNQ1,MYO9B,QSOX2,MYO1F,DOT1L,DTL,GNA12,L3MBTL3,JAZF1,ETV6,CAMKMT,PML,SUCLG2,ACBD4,MYO9A,ZMIZ1,FAM208A,TSEN15,CABLES1,SSSCA1,ZBTB24,RYBP |
| 2.093e-03 | -6.17 | MODULE_91 | MSigDB lists | MODULE_91 | 37 | 13 | 17377 | 2626 |
UBE2D3,PSMD2,PSMD1,H2AFZ,PSMA6,PSMD8,PSMD3,PSMB7,PSMA1,PSMD9,PSMC1,PSMB3,PSMC4 |
| 2.093e-03 | -6.17 | GO_RESPONSE_TO_NERVE_GROWTH_FACTOR | MSigDB lists | GO_RESPONSE_TO_NERVE_GROWTH_FACTOR | 37 | 13 | 17377 | 2626 |
RAP1A,KAT2A,EIF4A3,RAB35,E2F1,CIB1,CORO1A,CREB1,DNMT1,APP,CSNK1D,EEF2K,CDC5L |
| 2.093e-03 | -6.17 | BIOCARTA_INTEGRIN_PATHWAY | MSigDB lists | BIOCARTA_INTEGRIN_PATHWAY | 37 | 13 | 17377 | 2626 |
CRKL,RAP1A,RHOA,SHC1,CSK,RAF1,ITGB1,ROCK1,MAPK1,HRAS,MAP2K2,CAPN1,MAPK3 |
| 2.093e-03 | -6.17 | GO_TRICARBOXYLIC_ACID_METABOLIC_PROCESS | MSigDB lists | GO_TRICARBOXYLIC_ACID_METABOLIC_PROCESS | 37 | 13 | 17377 | 2626 |
SDHB,SUCLG1,MDH2,IDH3A,ACLY,CS,SUCLG2,DHTKD1,MDH1,GLUD1,OGDH,IDH3B,SDHA |
| 2.093e-03 | -6.17 | GO_PHAGOSOME_MATURATION | MSigDB lists | GO_PHAGOSOME_MATURATION | 37 | 13 | 17377 | 2626 |
ATP6V0B,RAB14,ATP6V1D,RAB7A,ATP6V0A2,ATP6V0A1,ATP6V0C,CORO1A,ATP6V1C1,ATP6V1B2,ATP6V0E1,ATP6V0D1,ATP6V1G1 |
| 2.095e-03 | -6.17 | endometriosis | COSMIC cancer mutations | endometriosis | 14 | 7 | 17385 | 2587 |
FGFR3,KRAS,ARID1A,BRCA1,NRAS,PTEN,HRAS |
| 2.095e-03 | -6.17 | urinary_tract-renal_pelvis-carcinoma-transitional_cell_carcinoma | COSMIC cancer mutations | urinary_tract-renal_pelvis-carcinoma-transitional_cell_carcinoma | 14 | 7 | 17385 | 2587 |
FGFR3,KRAS,NRAS,PTEN,VHL,HRAS,MSH6 |
| 2.095e-03 | -6.17 | ovary-sex_cord-stromal_tumour | COSMIC cancer mutations | ovary-sex_cord-stromal_tumour | 14 | 7 | 17385 | 2587 |
GNAS,STK11,H3F3A,STAT3,SF3B1,CDKN2A,PTPN11 |
| 2.097e-03 | -6.17 | UNKL (unkempt family like zinc finger) | protein interactions | 64718 | 10 | 6 | 17029 | 2761 |
SMAD2,PREPL,SMAD1,SMURF1,GGPS1,RAC1 |
| 2.097e-03 | -6.17 | CYTB (cytochrome b) | protein interactions | 4519 | 10 | 6 | 17029 | 2761 |
MRPL50,UQCRH,KRAS,CLDND1,CYC1,MVP |
| 2.097e-03 | -6.17 | MBD3L2 (methyl-CpG binding domain protein 3 like 2) | protein interactions | 125997 | 10 | 6 | 17029 | 2761 |
RBBP4,MBD3,MTA1,MTA2,MBD2,HDAC2 |
| 2.097e-03 | -6.17 | CERKL (ceramide kinase like) | protein interactions | 375298 | 10 | 6 | 17029 | 2761 |
ERBIN,ANKHD1,VHL,EIF3G,MICAL3,PPM1G |
| 2.097e-03 | -6.17 | PPCDC (phosphopantothenoylcysteine decarboxylase) | protein interactions | 60490 | 10 | 6 | 17029 | 2761 |
PSMA1,CENPT,WDYHV1,PPIG,DBI,PPCDC |
| 2.097e-03 | -6.17 | GPAM (glycerol-3-phosphate acyltransferase, mitochondrial) | protein interactions | 57678 | 10 | 6 | 17029 | 2761 |
SIRT2,CLU,IDE,APP,ECH1,PSMC4 |
| 2.097e-03 | -6.17 | Dclre1b (DNA cross-link repair 1B) | protein interactions | 140917 | 10 | 6 | 17029 | 2761 |
TERF2IP,TAF12,PARP10,POT1,TERF2,TXLNA |
| 2.097e-03 | -6.17 | ODC1 (ornithine decarboxylase 1) | protein interactions | 4953 | 10 | 6 | 17029 | 2761 |
GORASP2,TK1,ODC1,OAZ1,OAZ2,SSR1 |
| 2.099e-03 | -6.17 | mTOR signaling pathway | KEGG pathways | hsa04150 | 150 | 38 | 7161 | 1149 |
TSC2,RAF1,RPS6KA1,PRKAA1,LAMTOR3,RRAGC,AKT1S1,ATP6V1B2,FZD6,PTEN,PIK3R2,FNIP2,DVL2,SEH1L,MLST8,ATP6V1G1,PDPK1,TELO2,RHOA,NRAS,MIOS,AKT2,LRP5,KRAS,MAP2K2,RHEB,MAPK3,TSC1,ATP6V1D,WNT5B,LAMTOR4,WDR59,CAB39,STK11,DVL1,ATP6V1C1,MAPK1,HRAS |
| 2.099e-03 | -6.17 | mTOR signaling pathway | KEGG pathways | ko04150 | 150 | 38 | 7161 | 1149 |
TSC2,RAF1,RPS6KA1,PRKAA1,LAMTOR3,RRAGC,AKT1S1,ATP6V1B2,FZD6,PTEN,PIK3R2,FNIP2,DVL2,SEH1L,MLST8,ATP6V1G1,PDPK1,TELO2,RHOA,NRAS,MIOS,AKT2,LRP5,KRAS,MAP2K2,RHEB,MAPK3,TSC1,ATP6V1D,WNT5B,LAMTOR4,WDR59,CAB39,STK11,DVL1,ATP6V1C1,MAPK1,HRAS |
| 2.102e-03 | -6.17 | Proteasome Degradation | WikiPathways | WP183 | 66 | 20 | 5312 | 837 |
UBE2D3,H2AFZ,HLA-E,PSMB7,PSMA1,PSMB9,PSMD9,HLA-A,PSMB3,PSMC4,HLA-B,PSMD2,RPN1,PSMD1,PSMA6,PSMD8,PSMD3,H2AFX,RPN2,PSMC1 |
| 2.108e-03 | -6.16 | monovalent inorganic cation homeostasis | biological process | GO:0055067 | 142 | 35 | 17256 | 2622 |
KCTD7,SLC12A7,TM9SF4,GPR89A,SLC4A2,ATP5F1B,SLC12A9,ATP6V1B2,TMEM165,ATP6V0B,PDK2,CLIC4,ATP6V0A2,BCL2,SLC26A2,CLN6,SLC12A2,ATP6V0D1,ATP6V1G1,CHP1,CLCN3,PPT1,RAB7A,SLC26A6,ATP6V0A1,MAPK3,ATP6V1D,ATP1A1,ATP6V0C,ATP6V1C1,CLN3,MAPK1,ATP6V0E1,GPR89B,SNAPIN |
| 2.108e-03 | -6.16 | SKIL (SKI like proto-oncogene) | protein interactions | 6498 | 105 | 29 | 17029 | 2761 |
SRP72,CPNE1,NCOR2,RB1CC1,ZMYM5,TRAK1,CAMSAP1,UBE2I,EIF4G2,MACF1,PTPRF,C12orf10,OIP5,RB1,SMAD2,CDC16,CDC27,CHD3,AXIN1,PML,ZNF200,SNRNP70,MVP,SMAD1,SMAD4,HIPK3,THAP5,CBX4,FAF1 |
| 2.113e-03 | -6.16 | GSE9037_WT_VS_IRAK4_KO_LPS_4H_STIM_BMDM_DN | MSigDB lists | GSE9037_WT_VS_IRAK4_KO_LPS_4H_STIM_BMDM_DN | 190 | 44 | 17377 | 2626 |
MIF,HSPH1,LIME1,GMFG,ANXA6,DAP,CDT1,AP3M2,SIKE1,MXD4,BCL2L1,RFWD3,APLP2,CLUAP1,RAB21,RAB8A,CCNA2,TBC1D22A,DUT,TBC1D14,FNIP2,NCOA2,CAMK2G,FYTTD1,TRIM8,KLF10,EID1,MBLAC2,VHL,HELB,NFATC2,NDUFA7,BRCA1,ANLN,GINS4,RPA1,POLE,CORO1C,CEP55,GLG1,MPV17,UBE2C,CHID1,ACSF2 |
| 2.113e-03 | -6.16 | GSE17721_0.5H_VS_8H_GARDIQUIMOD_BMDC_DN | MSigDB lists | GSE17721_0.5H_VS_8H_GARDIQUIMOD_BMDC_DN | 190 | 44 | 17377 | 2626 |
TXN,GOLPH3L,GMFG,MYNN,TBC1D13,SLC4A2,PLXNA1,CCNL2,BECN1,WDR48,SPPL2A,ATP6V0B,NUS1,ATP2A2,DPYSL2,ZNF260,FEM1B,AP2B1,OSTF1,TNRC18,STAT3,UBE2M,FTSJ3,MORC3,ACSL5,PDPK1,GABPA,PSMB7,PITPNB,C9orf40,PPP2CA,HLA-B,RAB18,SYNCRIP,BRD2,CLK3,RBL1,TPP2,HNRNPH3,TBPL1,FAM122A,ZRANB2,HDAC2,PRPF4B |
| 2.113e-03 | -6.16 | GSE17186_CD21LOW_VS_CD21HIGH_TRANSITIONAL_BCELL_CORD_BLOOD_UP | MSigDB lists | GSE17186_CD21LOW_VS_CD21HIGH_TRANSITIONAL_BCELL_CORD_BLOOD_UP | 190 | 44 | 17377 | 2626 |
PIGN,GOLIM4,ABCA3,PDCD6IP,TRIP10,WDR13,RAC1,AGPAT3,SUMF1,TAF6L,B4GALT4,SLC12A9,SYNRG,GNB2,APP,PIP4K2A,EBP,DPYSL2,IL6ST,FAM89B,KIFAP3,TAP2,CLDND1,CITED2,ZNF710,ARID4A,PRPF19,ENPP4,SEPT9,USP22,GALNT7,RAB1A,HAUS8,GPR137,NUCB1,MKNK1,SCARB2,ATP6V1D,SURF4,CERS6,SNAP23,MYO9A,STARD3NL,PTOV1 |
| 2.113e-03 | -6.16 | GSE29949_CD8_NEG_DC_SPLEEN_VS_MONOCYTE_BONE_MARROW_UP | MSigDB lists | GSE29949_CD8_NEG_DC_SPLEEN_VS_MONOCYTE_BONE_MARROW_UP | 190 | 44 | 17377 | 2626 |
CYLD,FEZ2,RRP15,CAST,CENPF,KLHL18,REEP5,RNF103,SAC3D1,CAPN2,KDM2A,DPYSL2,ATP6V0A2,ANXA5,SPTSSA,AHCYL1,ORC3,GM2A,USP34,RBM15B,MLEC,ACSL3,E2F3,CDC6,MAT2A,UTP20,SEC23IP,ATP6V1D,PLAA,SPATA2,GOLGA8A,UBXN2B,TATDN2,DCK,UHRF2,SLC16A1,MEGF9,PITPNA,YWHAZ,ROCK1,PIEZO1,FAM208A,MAPK1,TUBB |
| 2.113e-03 | -6.16 | GSE42021_CD24HI_VS_CD24INT_TREG_THYMUS_DN | MSigDB lists | GSE42021_CD24HI_VS_CD24INT_TREG_THYMUS_DN | 190 | 44 | 17377 | 2626 |
DDX58,FAM208B,MAX,PARP12,HLA-E,TAP1,HLA-A,GSTK1,CTSS,PSMA6,CTNNBL1,SP100,IL6ST,LPIN2,GPATCH1,TAP2,ZNF710,TFG,STAT3,PPA1,TRIM14,USO1,TRAFD1,GUK1,LAP3,ASPM,SLC25A22,MCL1,OGFR,LY6E,PSMB9,PSMB3,FADD,ISG15,FAS,OPTN,HLA-B,NUCB1,STAT1,PML,RBMS1,APOL2,IFI16,RNF114 |
| 2.113e-03 | -6.16 | GSE7509_DC_VS_MONOCYTE_UP | MSigDB lists | GSE7509_DC_VS_MONOCYTE_UP | 190 | 44 | 17377 | 2626 |
TMEM106C,NDUFA5,TSC2,DAP,CDT1,TMEM109,TMED3,LANCL1,GYG1,RGS2,ITGB5,PITHD1,FOXO3,EBP,IL6ST,ANXA5,ANP32A,ATG13,CNN2,NDUFA3,CTDSP2,PPA1,FTSJ3,GM2A,KDELR1,EIF3L,CREG1,KIAA0930,RPL6,CADM1,UTP3,ARID1A,POLR2A,CBX3,PI4K2A,GNAS,CHCHD3,CDC16,TXNDC16,TWSG1,PSAP,PDXK,LTA4H,HEXA |
| 2.113e-03 | -6.16 | GSE17721_LPS_VS_CPG_24H_BMDC_DN | MSigDB lists | GSE17721_LPS_VS_CPG_24H_BMDC_DN | 190 | 44 | 17377 | 2626 |
UBE2D3,POLA2,PPIB,MIF4GD,EWSR1,TRIP10,STRN4,RRM1,PTP4A3,B4GALT1,ITGB5,PARN,LYN,MAN1A1,CTSS,SLC44A1,RAD23B,AP2B1,LTN1,RBM3,SLC35C2,PDIA6,ATP6V0D1,ILKAP,MSH6,HNRNPM,SMC4,ADAM17,TK1,PSRC1,BRD4,RAD51AP1,RPL6,VDAC1,SMAP2,PRDX1,SMAD2,UEVLD,RNF38,SIL1,PPP6R3,CCNB2,CDKN2A,TMEM131 |
| 2.113e-03 | -6.16 | GSE9650_NAIVE_VS_EFF_CD8_TCELL_DN | MSigDB lists | GSE9650_NAIVE_VS_EFF_CD8_TCELL_DN | 190 | 44 | 17377 | 2626 |
PPIB,SMAP1,NDUFB6,ANXA6,GNPDA1,DAP,PTTG1,AGPAT3,RACGAP1,SIRT2,TCF19,REEP5,REPS1,HLA-A,CAPN2,CDKN2C,DTL,MBD2,FAM89B,KIF22,MDFIC,S100A6,TMEM160,MAPRE2,PRIM2,TSPAN31,ARHGDIB,AURKB,FADD,MAPK3,MYO1F,AHNAK,JAK1,BIRC5,PSMD8,MRPL27,DBI,ITGB1,CTSA,HMGB2,ACTB,BTF3,RNF14,ATP6V0E1 |
| 2.113e-03 | -6.16 | GSE17721_LPS_VS_PAM3CSK4_24H_BMDC_UP | MSigDB lists | GSE17721_LPS_VS_PAM3CSK4_24H_BMDC_UP | 190 | 44 | 17377 | 2626 |
HSPH1,MRPL9,PARP12,TM9SF4,MDH2,GADD45G,RBM8A,CIB1,AP3M2,RAB23,EIF1B,MIEN1,METTL3,KCMF1,DDRGK1,FLAD1,GTPBP3,THAP4,PPIL2,FIZ1,TPST1,MDFIC,RBM3,MRPL11,RBM15,BAK1,POLR2G,TMEM39A,SNX2,DENND4C,FAM133B,NFATC2IP,METTL22,GFER,ARF4,PSMC4,GADD45B,DCAF11,GALNT10,MRPL13,CD81,NRBP1,TMEM33,RNF114 |
| 2.113e-03 | -6.16 | GSE42021_CD24LO_TREG_VS_CD24LO_TCONV_THYMUS_UP | MSigDB lists | GSE42021_CD24LO_TREG_VS_CD24LO_TCONV_THYMUS_UP | 190 | 44 | 17377 | 2626 |
MIF,ASH1L,FEZ2,PDAP1,UBXN1,LAGE3,CERK,NUP54,AGPAT3,JMJD6,MAPK14,FAM8A1,UBLCP1,VAV1,PSMD1,GART,TNFAIP8,AP3S2,TNPO3,TARDBP,ZNRD1,SAP30,YTHDC1,RFC3,BIRC3,CDC123,NUDT4,MAP4K4,KCTD20,GLO1,SMC2,RHOT1,PTTG1IP,TOLLIP,LUC7L,GFER,CYB5A,XRCC5,CDKN2AIPNL,GALNT2,TAB2,AXIN1,FAM3C,CHMP4B |
| 2.113e-03 | -6.16 | HALLMARK_ADIPOGENESIS | MSigDB lists | HALLMARK_ADIPOGENESIS | 190 | 44 | 17377 | 2626 |
NDUFA5,IMMT,SUCLG1,UQCR10,PPP1R15B,MDH2,MCCC1,TKT,UCK1,AGPAT3,EPHX2,REEP5,DNAJB9,CDKN2C,DECR1,APLP2,CRAT,TANK,CS,CYC1,TALDO1,DRAM2,SLC25A1,PREB,GPX4,BAZ2A,IDH3A,PFKFB3,MAP4K3,ESYT1,ECH1,SDHB,CAT,SLC19A1,PRDX3,ACOX1,ACLY,COX8A,ACADM,SCARB1,RTN3,ABCA1,TOB1,PDCD4 |
| 2.114e-03 | -6.16 | PID_P38_MK2_PATHWAY | MSigDB lists | PID_P38_MK2_PATHWAY | 21 | 9 | 17377 | 2626 |
TSC2,MAPKAPK3,RAF1,TCF3,YWHAZ,CDC25B,CREB1,MAPK14,YWHAH |
| 2.114e-03 | -6.16 | HOLLEMAN_PREDNISOLONE_RESISTANCE_B_ALL_UP | MSigDB lists | HOLLEMAN_PREDNISOLONE_RESISTANCE_B_ALL_UP | 21 | 9 | 17377 | 2626 |
PSRC1,HNRNPR,SUMO2,CS,UBE2Q1,CTCF,PCBP1,C7orf26,PRPF18 |
| 2.114e-03 | -6.16 | GO_MEMBRANE_PROTEIN_ECTODOMAIN_PROTEOLYSIS | MSigDB lists | GO_MEMBRANE_PROTEIN_ECTODOMAIN_PROTEOLYSIS | 21 | 9 | 17377 | 2626 |
ADAM17,ADAM10,APH1A,RBMX,ADAM9,MYH9,PSEN1,SPPL2B,SPPL2A |
| 2.114e-03 | -6.16 | GO_HYDROGEN_EXPORTING_ATPASE_ACTIVITY | MSigDB lists | GO_HYDROGEN_EXPORTING_ATPASE_ACTIVITY | 21 | 9 | 17377 | 2626 |
ATP6V0B,ATP6V0A1,ATP6V0A2,ATP6V0C,ATP6V1C1,ATP6V1B2,ATP6V0E1,ATP6V0D1,ATP6V1G1 |
| 2.114e-03 | -6.16 | GO_POSITIVE_REGULATION_OF_DNA_TEMPLATED_TRANSCRIPTION_ELONGATION | MSigDB lists | GO_POSITIVE_REGULATION_OF_DNA_TEMPLATED_TRANSCRIPTION_ELONGATION | 21 | 9 | 17377 | 2626 |
PAF1,HMGN1,BRD4,THOC1,CTR9,RTF1,CDC73,SUPT16H,GTF2F1 |
| 2.117e-03 | -6.16 | ACCAAAG,MIR-9 | MSigDB lists | ACCAAAG,MIR-9 | 469 | 94 | 17377 | 2626 |
TRAF7,GNPNAT1,TMEM109,WDTC1,KLHL18,MYH9,UBE2Z,UBE2Q1,TGOLN2,AGFG1,STAM,CMTM6,NRF1,RAB8A,SHC1,BRPF3,ZKSCAN1,TBC1D22A,GRSF1,FBXW2,TRA2B,BCAP29,RNF19A,SPTSSA,EIF5,MTPN,SCYL3,SENP1,CARM1,SRSF10,SNX25,FYTTD1,BRD4,GOPC,TLK1,PCGF6,ESYT1,ICMT,AP4E1,SLC50A1,DDX17,TAB2,NCOA1,FBXL3,REEP4,DYNC1LI2,POU3F2,NCOR2,SRSF6,ARFIP2,NOTCH2,DNAJB1,DCUN1D4,CSNK1A1,CDC73,HMG20A,ARID1B,LMNA,FBRS,CEP104,RIMS3,CAPZA1,ARHGEF2,FOXN2,SLC27A4,UBE3C,FBXL19,LUC7L2,SOCS5,CSNK1G2,PHF20L1,EMB,BCLAF1,UBE4B,ARID1A,LRRC1,ARPC1A,PI4K2A,NAP1L1,OSBPL11,MTHFD2,NEK1,MAGT1,CCDC6,PARG,TBPL1,C4orf46,PPP6R3,EHD4,BTBD10,PURA,CPEB2,IPO4,ESYT2 |
| 2.117e-03 | -6.16 | PPP2CB (protein phosphatase 2 catalytic subunit beta) | protein interactions | 5516 | 153 | 39 | 17029 | 2761 |
INTS2,FGFR1OP,TMEM41B,RAF1,STRN4,ENSA,SIKE1,FOXO3,PDCD10,PPME1,INTS1,PPP4R1,INTS12,ARHGEF2,CRY2,FGFR1OP2,MOB4,ANKLE2,CCT2,TCTEX1D2,STRIP1,NSUN2,MAP4K4,PACS1,PPFIA3,CCT8,TTC33,PPP2CA,PFDN5,PPP2R5A,CCDC6,TAB2,AXIN1,RPLP1,FAM122A,IGBP1,TERF1,PPP2R2D,IFI16 |
| 2.122e-03 | -6.16 | TPD52 (tumor protein D52) | protein interactions | 7163 | 47 | 16 | 17029 | 2761 |
ANXA6,MRPS2,EZR,PRKACA,PAIP1,MEAF6,TPD52L2,CLIC4,SAR1A,DUT,PTGES3,PDLIM5,PDIA6,MTX2,PDCD4,SRPK2 |
| 2.122e-03 | -6.16 | RCC2 (regulator of chromosome condensation 2) | protein interactions | 55920 | 47 | 16 | 17029 | 2761 |
RAC1,CDCA8,RACGAP1,AURKB,SRSF5,SNRPD3,MCM2,DOCK11,CDC42,PTEN,CORO1C,EIF2D,BUD31,CDK2,HNRNPM,DEF6 |
| 2.123e-03 | -6.15 | cellular response to organonitrogen compound | biological process | GO:0071417 | 501 | 100 | 17256 | 2622 |
MAX,DNMT3A,UBR2,WDTC1,RRAGC,BCL2L1,SIRT2,ATP6V1B2,PRKACA,LYN,GNB2,APP,PRNP,EEF2K,CDK5,USF1,ATP6V0B,PDK2,RAB8A,CCNA2,RAP1A,MDM2,SHC1,ADCY9,PIK3R2,DNM2,AKR1B1,AHCYL1,DNMT1,SPIDR,ATP6V1G1,ADCY7,CDC5L,LARS,KLF10,GABPA,AKT2,GNG7,SLC26A6,ATP6V0A1,EZR,CDC6,BRCA1,SOCS7,IDE,STAT1,ATP6V0C,ACTB,MAPK1,ATP6V0E1,C2CD5,HDAC2,SLC25A33,GCLM,CASP6,AGTRAP,PRKAA1,LAMTOR3,BLM,PSEN1,AP3S1,FOXO3,ARID1B,CFLAR,PTPN2,CAPN2,PDXP,PTEN,ARHGEF2,ATP6V0A2,TIMELESS,CREB1,STAT3,ATP6V0D1,MYO5A,TGFB1,PDPK1,CYFIP1,PPP1R9B,PRKDC,DENND4C,PRKAR1B,RANGAP1,SRSF5,KCNQ1,ADRB2,MEN1,PKM,PDE3B,APPL1,MAPK3,EPRS,CACNB1,ATP6V1D,CSK,NSMF,LAMTOR4,PKD2,ATP6V1C1,CPEB2 |
| 2.126e-03 | -6.15 | E2F_TDP | smart domains | SM01372 | 11 | 6 | 9493 | 1367 |
TFDP2,E2F2,E2F4,TFDP1,E2F1,E2F3 |
| 2.130e-03 | -6.15 | central_nervous_system-spinal_cord-atypical_teratoid-rhabdoid_tumour | COSMIC cancer mutations | central_nervous_system-spinal_cord-atypical_teratoid-rhabdoid_tumour | 60 | 18 | 17385 | 2587 |
NRAS,NF1,VHL,KRAS,BRCA1,KMT2C,MEN1,GNAS,RB1,FGFR3,PTEN,MSH2,PTPN11,STK11,SMAD4,HRAS,MSH6,CDKN2A |
| 2.135e-03 | -6.15 | GAB2 (GRB2 associated binding protein 2) | protein interactions | 9846 | 82 | 24 | 17029 | 2761 |
NCK1,NF1,FAM53C,DENND4C,E2F3,RAB3IP,LYN,MARK2,USP21,GIGYF1,MAPK3,RTKN,CRKL,ZBTB21,SHC1,FAM110A,KIF13B,PIK3R2,ETV6,E2F1,PTPN11,CDC25B,E2F2,MAPK1 |
| 2.136e-03 | -6.15 | PTTG1 (pituitary tumor-transforming 1) | protein interactions | 9232 | 73 | 22 | 17029 | 2761 |
HNRNPAB,RAE1,PTTG1,RPS10,XIAP,EZR,CUL1,ANAPC2,DNAJA1,UBE4A,PTTG1IP,POLR3K,RAD23A,DECR1,PPP2R5A,SYNCRIP,CDC27,LUC7L3,MAPK1,PPP2R2D,ESPL1,ZC3H3 |
| 2.136e-03 | -6.15 | ABCD3 (ATP binding cassette subfamily D member 3) | protein interactions | 5825 | 73 | 22 | 17029 | 2761 |
UNK,TIMMDC1,RAB7A,TAP1,DHX9,CUL3,PSMA1,PTP4A3,NDUFA4,KRAS,TOMM40,NDUFS4,PCM1,NDUFV1,PELO,ZNF746,MPV17,PGRMC1,USP32,ABCD1,ATP6V1C1,CLN3 |
| 2.136e-03 | -6.15 | PPP2R5D (protein phosphatase 2 regulatory subunit B'delta) | protein interactions | 5528 | 73 | 22 | 17029 | 2761 |
LARS,DHPS,GOPC,DNAAF5,RRM2,RANGAP1,SH3GLB1,PRDX1,PTPRF,PPP2CA,RPA2,PON2,PFDN5,TPD52L2,NEK1,PPP2R5A,PPME1,CTR9,CRY2,CHEK2,FBXL3,PPP2R2D |
| 2.142e-03 | -6.15 | PROTEIN_KINASE_ST | prosite domains | PS00108 | 308 | 61 | 12060 | 1670 |
RAF1,RPS6KA1,PRKAA1,TRIO,CSNK2A1,CDK13,EIF2AK4,CDK11B,CSNK1A1,PRKACA,CDK5,PRKD3,GRK2,NEK6,DAPK1,MAST2,MAP3K14,CDK12,PHKG2,CSNK1G3,CAMK2G,SRPK2,PLK3,PDPK1,PLK1,CSNK1G2,ULK3,MAPKAPK3,NEK7,AKT2,PBK,TAOK1,MAP4K4,TLK1,EIF2AK1,PKMYT1,AURKB,CDK11A,STK17B,MARK2,MAP2K2,DAPK3,MAPK3,MASTL,MAP3K4,MKNK1,NEK1,CLK3,CSNK1G1,HIPK2,STK38,MAPK6,STK11,CHEK2,ROCK1,MAP3K5,MAPK1,CDK2,HIPK3,CSNK1D,PRPF4B |
| 2.143e-03 | -6.15 | transport along microtubule | biological process | GO:0010970 | 137 | 34 | 17256 | 2622 |
KIF3B,DYNLL1,TRAK1,AP3M2,KIF23,RAB6A,AP3S1,IFT27,APP,COPG2,DST,KIF5B,CLUAP1,RAB21,CDC42,AP3S2,KIFAP3,IFT46,TERF2,DCTN1,BICD2,FXR1,RHOT1,RAB1A,RHOT2,BBS12,TMEM201,PCM1,HSPB11,LRPPRC,SSNA1,CLN3,NDE1,SNAPIN |
| 2.143e-03 | -6.15 | microtubule-based transport | biological process | GO:0099111 | 137 | 34 | 17256 | 2622 |
KIF3B,DYNLL1,TRAK1,AP3M2,KIF23,RAB6A,AP3S1,IFT27,APP,COPG2,DST,KIF5B,CLUAP1,RAB21,CDC42,AP3S2,KIFAP3,IFT46,TERF2,DCTN1,BICD2,FXR1,RHOT1,RAB1A,RHOT2,BBS12,TMEM201,PCM1,HSPB11,LRPPRC,SSNA1,CLN3,NDE1,SNAPIN |
| 2.154e-03 | -6.14 | GO_VESICLE_LOCALIZATION | MSigDB lists | GO_VESICLE_LOCALIZATION | 217 | 49 | 17377 | 2626 |
KIF3B,DNAJC5,GORASP1,RAB11B,DCTN2,AP3M2,KIF23,ARF1,AP3S1,SEC16A,PSEN1,RAB11A,PIP5K1C,ANKRD28,CDK5,KIF5B,CD59,AP3S2,DPYSL2,SEC24C,PPP6C,DNM2,KIFAP3,TFG,LMAN1,PPP6R1,SYTL3,TMED2,MYO5A,PREB,DCTN1,USO1,TRAPPC9,CUL3,WDR81,MCFD2,RAB1A,SEC31A,SEC23IP,GOLGA2,NSF,TMED10,SNAP23,SNAP29,PPP6R3,CLN3,NDE1,CSNK1D,SNAPIN |
| 2.156e-03 | -6.14 | skin-forearm-other-lichenoid_keratosis | COSMIC cancer mutations | skin-forearm-other-lichenoid_keratosis | 5 | 4 | 17385 | 2587 |
FGFR3,KRAS,NRAS,HRAS |
| 2.156e-03 | -6.14 | skin-leg-other-keratoacanthoma | COSMIC cancer mutations | skin-leg-other-keratoacanthoma | 5 | 4 | 17385 | 2587 |
KRAS,NRAS,HRAS,CDKN2A |
| 2.156e-03 | -6.14 | skin-ear-other-nevus_sebaceous | COSMIC cancer mutations | skin-ear-other-nevus_sebaceous | 5 | 4 | 17385 | 2587 |
FGFR3,KRAS,NRAS,HRAS |
| 2.156e-03 | -6.14 | skin-trunk-other-keratoacanthoma | COSMIC cancer mutations | skin-trunk-other-keratoacanthoma | 5 | 4 | 17385 | 2587 |
KRAS,NRAS,HRAS,CDKN2A |
| 2.156e-03 | -6.14 | skin-upper_leg-other-lichenoid_keratosis | COSMIC cancer mutations | skin-upper_leg-other-lichenoid_keratosis | 5 | 4 | 17385 | 2587 |
FGFR3,KRAS,NRAS,HRAS |
| 2.156e-03 | -6.14 | skin-chest-carcinoma-basal_cell_carcinoma | COSMIC cancer mutations | skin-chest-carcinoma-basal_cell_carcinoma | 5 | 4 | 17385 | 2587 |
KRAS,CYLD,NRAS,HRAS |
| 2.156e-03 | -6.14 | skin-adnexal_tumour-syringocystadenoma_papilliferum | COSMIC cancer mutations | skin-adnexal_tumour-syringocystadenoma_papilliferum | 5 | 4 | 17385 | 2587 |
FGFR3,KRAS,NRAS,HRAS |
| 2.156e-03 | -6.14 | skin-face-other-nevus_sebaceous | COSMIC cancer mutations | skin-face-other-nevus_sebaceous | 5 | 4 | 17385 | 2587 |
FGFR3,KRAS,NRAS,HRAS |
| 2.156e-03 | -6.14 | skin-upper_back-other-lichenoid_keratosis | COSMIC cancer mutations | skin-upper_back-other-lichenoid_keratosis | 5 | 4 | 17385 | 2587 |
FGFR3,KRAS,NRAS,HRAS |
| 2.156e-03 | -6.14 | skin-neck-other-lichenoid_keratosis | COSMIC cancer mutations | skin-neck-other-lichenoid_keratosis | 5 | 4 | 17385 | 2587 |
FGFR3,KRAS,NRAS,HRAS |
| 2.156e-03 | -6.14 | skin-lower_back-other-lichenoid_keratosis | COSMIC cancer mutations | skin-lower_back-other-lichenoid_keratosis | 5 | 4 | 17385 | 2587 |
FGFR3,KRAS,NRAS,HRAS |
| 2.156e-03 | -6.14 | skin-trunk-carcinoma-squamous_cell_carcinoma | COSMIC cancer mutations | skin-trunk-carcinoma-squamous_cell_carcinoma | 5 | 4 | 17385 | 2587 |
KRAS,NRAS,HRAS,CDKN2A |
| 2.156e-03 | -6.14 | skin-head_neck-other-keratoacanthoma | COSMIC cancer mutations | skin-head_neck-other-keratoacanthoma | 5 | 4 | 17385 | 2587 |
KRAS,NRAS,HRAS,CDKN2A |
| 2.156e-03 | -6.14 | upper_aerodigestive_tract-mouth-other-leukoplakia-hyperplakia-erythroplakia | COSMIC cancer mutations | upper_aerodigestive_tract-mouth-other-leukoplakia-hyperplakia-erythroplakia | 5 | 4 | 17385 | 2587 |
KRAS,NRAS,HRAS,CDKN2A |
| 2.156e-03 | -6.14 | skin-face-other-lichenoid_keratosis | COSMIC cancer mutations | skin-face-other-lichenoid_keratosis | 5 | 4 | 17385 | 2587 |
FGFR3,KRAS,NRAS,HRAS |
| 2.156e-03 | -6.14 | ependymoma_Grade_I | COSMIC cancer mutations | ependymoma_Grade_I | 5 | 4 | 17385 | 2587 |
TSC1,TSC2,MEN1,CDKN2A |
| 2.156e-03 | -6.14 | lung-right-other-papilloma | COSMIC cancer mutations | lung-right-other-papilloma | 5 | 4 | 17385 | 2587 |
KRAS,NRAS,HRAS,CDKN2A |
| 2.156e-03 | -6.14 | skin-lower_back-other-nevus_sebaceous | COSMIC cancer mutations | skin-lower_back-other-nevus_sebaceous | 5 | 4 | 17385 | 2587 |
FGFR3,KRAS,NRAS,HRAS |
| 2.156e-03 | -6.14 | haematopoietic_and_lymphoid_tissue-liver-lymphoid_neoplasm-diffuse_large_B_cell_lymphoma | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-liver-lymphoid_neoplasm-diffuse_large_B_cell_lymphoma | 5 | 4 | 17385 | 2587 |
RB1,KRAS,NRAS,HRAS |
| 2.156e-03 | -6.14 | skin-lower_leg-other-lichenoid_keratosis | COSMIC cancer mutations | skin-lower_leg-other-lichenoid_keratosis | 5 | 4 | 17385 | 2587 |
FGFR3,KRAS,NRAS,HRAS |
| 2.156e-03 | -6.14 | skin-flank-other-lichenoid_keratosis | COSMIC cancer mutations | skin-flank-other-lichenoid_keratosis | 5 | 4 | 17385 | 2587 |
FGFR3,KRAS,NRAS,HRAS |
| 2.156e-03 | -6.14 | autonomic_ganglia-abdomen-paraganglioma | COSMIC cancer mutations | autonomic_ganglia-abdomen-paraganglioma | 5 | 4 | 17385 | 2587 |
MAX,MEN1,NF1,VHL |
| 2.156e-03 | -6.14 | skin-scalp-other-nevus_sebaceous | COSMIC cancer mutations | skin-scalp-other-nevus_sebaceous | 5 | 4 | 17385 | 2587 |
FGFR3,KRAS,NRAS,HRAS |
| 2.156e-03 | -6.14 | skin-hand-other-lichenoid_keratosis | COSMIC cancer mutations | skin-hand-other-lichenoid_keratosis | 5 | 4 | 17385 | 2587 |
FGFR3,KRAS,NRAS,HRAS |
| 2.156e-03 | -6.14 | upper_aerodigestive_tract-trachea-other-papilloma | COSMIC cancer mutations | upper_aerodigestive_tract-trachea-other-papilloma | 5 | 4 | 17385 | 2587 |
KRAS,NRAS,HRAS,CDKN2A |
| 2.156e-03 | -6.14 | skin-breast-other-nevus_sebaceous | COSMIC cancer mutations | skin-breast-other-nevus_sebaceous | 5 | 4 | 17385 | 2587 |
FGFR3,KRAS,NRAS,HRAS |
| 2.156e-03 | -6.14 | xanthomatous | COSMIC cancer mutations | xanthomatous | 5 | 4 | 17385 | 2587 |
KRAS,NRAS,PTEN,HRAS |
| 2.156e-03 | -6.14 | skin-shoulder-other-nevus_sebaceous | COSMIC cancer mutations | skin-shoulder-other-nevus_sebaceous | 5 | 4 | 17385 | 2587 |
FGFR3,KRAS,NRAS,HRAS |
| 2.156e-03 | -6.14 | minor | COSMIC cancer mutations | minor | 5 | 4 | 17385 | 2587 |
KRAS,NRAS,HRAS,ETV6 |
| 2.156e-03 | -6.14 | thyroid-adenoma-nodule-goitre-Hurthle_cell_tumour | COSMIC cancer mutations | thyroid-adenoma-nodule-goitre-Hurthle_cell_tumour | 5 | 4 | 17385 | 2587 |
KRAS,NRAS,CCDC6,HRAS |
| 2.156e-03 | -6.14 | lichenoid_keratosis | COSMIC cancer mutations | lichenoid_keratosis | 5 | 4 | 17385 | 2587 |
FGFR3,KRAS,NRAS,HRAS |
| 2.156e-03 | -6.14 | skin-other-lichenoid_keratosis | COSMIC cancer mutations | skin-other-lichenoid_keratosis | 5 | 4 | 17385 | 2587 |
FGFR3,KRAS,NRAS,HRAS |
| 2.156e-03 | -6.14 | skin-neck-other-nevus_sebaceous | COSMIC cancer mutations | skin-neck-other-nevus_sebaceous | 5 | 4 | 17385 | 2587 |
FGFR3,KRAS,NRAS,HRAS |
| 2.156e-03 | -6.14 | Hurthle_cell_tumour | COSMIC cancer mutations | Hurthle_cell_tumour | 5 | 4 | 17385 | 2587 |
KRAS,NRAS,CCDC6,HRAS |
| 2.156e-03 | -6.14 | syringocystadenoma_papilliferum | COSMIC cancer mutations | syringocystadenoma_papilliferum | 5 | 4 | 17385 | 2587 |
FGFR3,KRAS,NRAS,HRAS |
| 2.156e-03 | -6.14 | skin-chest-other-lichenoid_keratosis | COSMIC cancer mutations | skin-chest-other-lichenoid_keratosis | 5 | 4 | 17385 | 2587 |
FGFR3,KRAS,NRAS,HRAS |
| 2.156e-03 | -6.14 | leukoplakia-hyperplakia-erythroplakia | COSMIC cancer mutations | leukoplakia-hyperplakia-erythroplakia | 5 | 4 | 17385 | 2587 |
KRAS,NRAS,HRAS,CDKN2A |
| 2.156e-03 | -6.14 | large_intestine-anus-carcinoma-adenocarcinoma | COSMIC cancer mutations | large_intestine-anus-carcinoma-adenocarcinoma | 5 | 4 | 17385 | 2587 |
KRAS,NRAS,HRAS,CDKN2A |
| 2.156e-03 | -6.14 | skin-breast-other-lichenoid_keratosis | COSMIC cancer mutations | skin-breast-other-lichenoid_keratosis | 5 | 4 | 17385 | 2587 |
FGFR3,KRAS,NRAS,HRAS |
| 2.156e-03 | -6.14 | submaxillary | COSMIC cancer mutations | submaxillary | 5 | 4 | 17385 | 2587 |
KRAS,NRAS,SF3B1,HRAS |
| 2.156e-03 | -6.14 | meninges-meningioma-xanthomatous | COSMIC cancer mutations | meninges-meningioma-xanthomatous | 5 | 4 | 17385 | 2587 |
KRAS,NRAS,PTEN,HRAS |
| 2.156e-03 | -6.14 | skin-shoulder-other-lichenoid_keratosis | COSMIC cancer mutations | skin-shoulder-other-lichenoid_keratosis | 5 | 4 | 17385 | 2587 |
FGFR3,KRAS,NRAS,HRAS |
| 2.156e-03 | -6.14 | skin-arm-malignant_melanoma-nodular | COSMIC cancer mutations | skin-arm-malignant_melanoma-nodular | 5 | 4 | 17385 | 2587 |
KRAS,NRAS,PTEN,HRAS |
| 2.156e-03 | -6.14 | urinary_tract-renal_pelvis-carcinoma | COSMIC cancer mutations | urinary_tract-renal_pelvis-carcinoma | 5 | 4 | 17385 | 2587 |
KRAS,NRAS,HRAS,CDKN2A |
| 2.156e-03 | -6.14 | skin-upper_arm-other-lichenoid_keratosis | COSMIC cancer mutations | skin-upper_arm-other-lichenoid_keratosis | 5 | 4 | 17385 | 2587 |
FGFR3,KRAS,NRAS,HRAS |
| 2.156e-03 | -6.14 | GSE13547_WT_VS_ZFX_KO_BCELL_DN | MSigDB lists | GSE13547_WT_VS_ZFX_KO_BCELL_DN | 169 | 40 | 17377 | 2626 |
PTMS,H2AFZ,FAM129A,UFC1,CDCA8,HMGN3,HAUS4,GYG1,FKBP2,STMN1,RGS1,CALM2,RPA2,IRF4,ERH,CLIC4,PSMA6,CCDC50,SYTL3,TACC3,GINS1,TXNL1,RFC3,KIF15,LDHA,MKI67,NLN,CCDC34,PSMA1,KIF11,PRIM1,HMGN2,RAD18,PSMD8,GADD45B,DBI,NFIL3,NRM,COX5A,ATF6 |
| 2.169e-03 | -6.13 | PID_MYC_ACTIV_PATHWAY | MSigDB lists | PID_MYC_ACTIV_PATHWAY | 78 | 22 | 17377 | 2626 |
TK1,MAX,KAT2A,NDUFAF2,SLC2A1,E2F3,LDHA,CCNB1,SUPT7L,ODC1,TFRC,RPL11,UBTF,HSPA4,PDCD10,BIRC5,HUWE1,PRDX3,MTA1,TAF12,RUVBL2,SMAD4 |
| 2.179e-03 | -6.13 | sex_cord-stromal_tumour | COSMIC cancer mutations | sex_cord-stromal_tumour | 42 | 14 | 17385 | 2587 |
GNAS,CDKN2C,DNMT3A,NRAS,PTEN,SF3B1,PTPN11,STK11,KRAS,BRCA1,H3F3A,STAT3,HRAS,CDKN2A |
| 2.180e-03 | -6.13 | TTCNRGNNNNTTC_V$HSF_Q6 | MSigDB lists | TTCNRGNNNNTTC_V$HSF_Q6 | 143 | 35 | 17377 | 2626 |
HSPH1,ST13,ZBTB37,JMJD6,XPNPEP3,MXD4,HNRNPA2B1,ZNF428,NFATC3,TNFAIP8,DPYSL2,AHSA1,UPF2,PRADC1,ZNF800,ABHD2,NUDT4,ATP2C1,E2F3,RANGAP1,NUTF2,DNAJA1,CCT8,PHF6,MAT2A,HSPA1B,CBX3,DDX17,KRIT1,JAK1,TBPL1,ZMIZ1,PURA,LRP8,PTOV1 |
| 2.180e-03 | -6.13 | Abhydrolase_6 | pfam domains | PF12697 | 5 | 4 | 17054 | 2545 |
ABHD14B,ABHD11,PPME1,ABHD14A |
| 2.180e-03 | -6.13 | FtsJ | pfam domains | PF01728 | 5 | 4 | 17054 | 2545 |
CMTR2,FTSJ3,FTSJ1,MRM2 |
| 2.180e-03 | -6.13 | SOAT1 (sterol O-acyltransferase 1) | protein interactions | 6646 | 168 | 42 | 17029 | 2761 |
NDUFA5,PDCD6IP,NDUFS1,TXN,MDH2,TKT,COX4I1,ARF1,OAT,RAB11A,SCYL2,PIP5K1C,GART,IARS,BANF1,RTCB,RPN2,TECR,FBL,CHTOP,LDHB,EIF5A,MKLN1,RAB7A,MRPL12,LDHA,TMEM216,VDAC2,MTMR6,ATP5MF,VDAC1,SLC25A5,EVC2,STOML2,EPRS,NAP1L1,PRDX3,SLC16A1,YWHAZ,CHMP4B,TERF1,TSPAN5 |
| 2.183e-03 | -6.13 | response to insulin | biological process | GO:0032868 | 216 | 49 | 17256 | 2622 |
MAX,SRSF6,SLC2A1,WDTC1,ATP6V1B2,LYN,AP3S1,EEF2K,CFLAR,PTPN2,USF1,RAB8A,ATP6V0B,PDK2,SHC1,PTEN,GOT2,PIK3R2,SRSF4,UPRT,ATP6V0A2,ATP6V0D1,MYO5A,ATP6V1G1,PDPK1,CYFIP1,AKT2,PRKDC,DENND4C,ATP6V0A1,SRSF5,PKM,PDE3B,APPL1,SOCS7,CAT,EPRS,TSC1,IDE,ATP6V1D,SCAP,STAT1,OGT,ATP6V0C,ATP6V1C1,CPEB2,C2CD5,ATP6V0E1,SLC25A33 |
| 2.188e-03 | -6.12 | GSE17721_PAM3CSK4_VS_CPG_8H_BMDC_DN | MSigDB lists | GSE17721_PAM3CSK4_VS_CPG_8H_BMDC_DN | 185 | 43 | 17377 | 2626 |
COX15,FAM208B,SARNP,GOLPH3L,DCAF15,TRIP10,HLA-E,AP3M2,PCSK7,NIPA2,CPNE3,MXD1,NDUFS4,ARL6IP6,FKBP1A,USF1,MDM2,MBD2,UPF2,TFG,MYO5A,FYTTD1,ENPP4,TK1,ATP13A1,CSRP1,LNX2,DNAJA1,BRCA1,HERPUD2,KLF6,ARF4,NMT2,SMAP2,HLA-B,TMEM168,MRPL27,CHMP4B,PLOD3,MRPL13,CDKN2A,STARD3NL,RNF114 |
| 2.188e-03 | -6.12 | GSE40068_CXCR5NEG_BCL6NEG_CD4_TCELL_VS_CXCR5POS_BCL6NEG_TFH_UP | MSigDB lists | GSE40068_CXCR5NEG_BCL6NEG_CD4_TCELL_VS_CXCR5POS_BCL6NEG_TFH_UP | 185 | 43 | 17377 | 2626 |
CCNC,UGP2,UQCR10,B4GALT5,RHOC,PCSK7,MYEF2,RGS1,SSR1,OIP5,CAPN2,RAB8A,NUS1,ATP2A2,GTSE1,NDUFB9,OSTF1,TFG,SGCB,SAP30,RFC3,SEC61B,PRIM2,RBX1,NEK7,LACTB,WDHD1,NFATC2,NUTF2,BORA,PICALM,RHBDF2,HSPA1B,OPTN,RAD51C,HINT1,NEIL3,NFIL3,ITGB1,C4orf46,NUP62,REEP4,NGLY1 |
| 2.188e-03 | -6.12 | GSE17721_CTRL_VS_LPS_2H_BMDC_UP | MSigDB lists | GSE17721_CTRL_VS_LPS_2H_BMDC_UP | 185 | 43 | 17377 | 2626 |
RHOG,UNK,NSMCE4A,MRPS15,GNE,CDT1,HEXB,SLC39A13,SEC16A,XPR1,SMC3,DAD1,MTA1,ARL6IP1,TIMELESS,CYB5R1,SLC26A2,TMEM14C,POC5,MSH6,ELOF1,GPX4,SNX2,ERLIN1,RPL6,SEPT8,HTATIP2,FBXO9,TMEM147,ASF1B,TFEB,DDX17,MFAP1,RPS14,STK38,CDCA7L,PPM1G,CRCP,MLYCD,PTDSS1,NUDT3,FAF1,CCDC137 |
| 2.188e-03 | -6.12 | GSE23505_UNTREATED_VS_4DAY_IL6_IL1_TREATED_CD4_TCELL_UP | MSigDB lists | GSE23505_UNTREATED_VS_4DAY_IL6_IL1_TREATED_CD4_TCELL_UP | 185 | 43 | 17377 | 2626 |
NDUFV2,AGTRAP,DYNLL1,MDH2,UFC1,RAC1,SPR,PITHD1,DTL,FLAD1,TNS3,NDUFA2,CBWD2,STRBP,NT5DC1,MCM5,YIF1B,BCL2,AHCY,CENPM,APOOL,FAM3A,LRSAM1,TRIM14,MED22,PDCL3,CDC123,PRKDC,METTL5,PSMA1,CCDC34,ELP4,CHCHD6,FKBP3,CYB5A,ECH1,PRDX1,RPA1,C1orf122,PRIM1,CAT,TONSL,RBL1 |
| 2.188e-03 | -6.12 | GSE5142_HTERT_TRANSDUCED_VS_CTRL_CD8_TCELL_LATE_PASSAGE_CLONE_DN | MSigDB lists | GSE5142_HTERT_TRANSDUCED_VS_CTRL_CD8_TCELL_LATE_PASSAGE_CLONE_DN | 185 | 43 | 17377 | 2626 |
CDS2,PDCD6IP,PHF23,KLHL21,TSC22D3,PTTG1,TRIO,CDC42SE2,RGS2,ETS1,DNAJB9,KIAA1147,SPPL2A,INPP5A,KIF13B,DAPK1,CRY2,CABLES2,TMEM8A,FRMD8,ABCC5,RYBP,SHOC2,ETV3,ZMYM5,KIAA0930,FRAT2,KRAS,ARID1A,PTTG1IP,KLF6,RHOB,SERTAD2,GALNT2,PEX5,L3MBTL3,SETD3,GLG1,YY1,MYO9A,SMAD4,NUMB,RHEBL1 |
| 2.188e-03 | -6.12 | GSE3982_DC_VS_NEUTROPHIL_LPS_STIM_UP | MSigDB lists | GSE3982_DC_VS_NEUTROPHIL_LPS_STIM_UP | 185 | 43 | 17377 | 2626 |
DNAJC2,NDUFV2,PDCD6IP,MRPL39,TOR3A,PPP3CB,COPB2,PAPOLA,SEC11A,EIF2S2,COQ4,GOT2,PRDM4,NUP107,NOC2L,GPATCH1,NDUFS8,SMARCE1,MICAL3,ALDH9A1,ABCC1,LDHB,RPL35,FAM172A,HMGN5,HARS,NSDHL,TMEM126B,GORASP2,EAF2,CDC23,SUGP1,RAD51C,DAP3,KEAP1,PALB2,MAGT1,PTER,PRPS2,COX5A,ACAT1,MRFAP1L1,RUFY3 |
| 2.188e-03 | -6.12 | BILD_MYC_ONCOGENIC_SIGNATURE | MSigDB lists | BILD_MYC_ONCOGENIC_SIGNATURE | 185 | 43 | 17377 | 2626 |
SRM,NOP2,SESTD1,TMEM97,CDCA8,DUSP22,C19orf48,CFLAR,PCYOX1L,FLAD1,ABL2,FARSA,PA2G4,VMP1,ATIC,FAM86C1,TTLL12,GPD1L,SPTAN1,METTL1,DDX28,ERCC1,OSBP2,SCFD2,PLEC,LSG1,GEMIN5,ALG3,UTP20,MKNK1,SLC19A1,AHNAK,GOLGA2,CCDC86,ARNTL,TCOF1,BEND3,NDE1,SMURF1,CDK2,GPATCH4,IPO4,CCDC137 |
| 2.188e-03 | -6.12 | GSE11961_GERMINAL_CENTER_BCELL_DAY7_VS_PLASMA_CELL_DAY7_DN | MSigDB lists | GSE11961_GERMINAL_CENTER_BCELL_DAY7_VS_PLASMA_CELL_DAY7_DN | 185 | 43 | 17377 | 2626 |
GXYLT1,ZNF768,HEXB,SLC39A13,TPX2,SUMF1,PCBP1,REEP5,KTN1,PRNP,ATP6V0B,CLIC4,CWC27,MCM5,TANK,MDFIC,ZNF710,ARID4A,DRAM2,TERF2,SRSF10,CYFIP1,PGGT1B,MKI67,CKAP2L,PPWD1,DHX57,OPTN,CAT,TSC1,HSPA4,SMAD2,WDR11,TMEM168,TXNDC16,BRWD1,TOMM6,MYO18A,KBTBD7,SLC25A19,ZFP90,MAP3K5,NDE1 |
| 2.192e-03 | -6.12 | SAP | smart domains | SM00513 | 22 | 9 | 9493 | 1367 |
SARNP,RAD18,SAFB,HNRNPUL2,PIAS2,SAFB2,SLTM,CCAR1,SF3B2 |
| 2.193e-03 | -6.12 | regulation of extrinsic apoptotic signaling pathway via death domain receptors | biological process | GO:1902041 | 59 | 18 | 17256 | 2622 |
TNFAIP3,NF1,RAF1,RFFL,BRCA1,BCL2L1,PARK7,FADD,FAS,CFLAR,SP100,PTEN,DAPK1,FEM1B,ARHGEF2,HMGB2,TMBIM1,FAF1 |
| 2.196e-03 | -6.12 | NT5C2 (5'-nucleotidase, cytosolic II) | protein interactions | 22978 | 31 | 12 | 17029 | 2761 |
HSPBP1,DUSP3,GNPDA1,SNX15,BTF3L4,ADSL,PTGES3,EHD4,API5,SZRD1,USP5,RAD23A |
| 2.196e-03 | -6.12 | PYCR2 (pyrroline-5-carboxylate reductase 2) | protein interactions | 29920 | 31 | 12 | 17029 | 2761 |
TNS3,SKA3,AHNAK,CDC16,CIC,MYO18A,CUL3,CDC23,APP,NPLOC4,TERF2,MYO1F |
| 2.196e-03 | -6.12 | vIRF-4 (interferon regulatory factor) | protein interactions | 4961495 | 31 | 12 | 17029 | 2761 |
ANKZF1,NSA2,RECQL,CDC16,CDC27,CHD3,ZNF316,DHX29,TAOK1,MRPL34,BLM,MRPL32 |
| 2.196e-03 | -6.12 | CNOT6L (CCR4-NOT transcription complex subunit 6 like) | protein interactions | 246175 | 31 | 12 | 17029 | 2761 |
CNOT9,LZTR1,GPBP1L1,BTG2,GADD45B,AGO2,CNOT6,CAPZA2,CNOT11,TOB1,CNOT3,CHAF1A |
| 2.196e-03 | -6.12 | EDNRB (endothelin receptor type B) | protein interactions | 1910 | 31 | 12 | 17029 | 2761 |
GRK2,THADA,C1orf112,BTAF1,TNPO2,INTS12,KNTC1,XPO7,ECPAS,PDXDC1,CIP2A,TYW1B |
| 2.198e-03 | -6.12 | regulation of ubiquitin protein ligase activity | biological process | GO:1904666 | 21 | 9 | 17256 | 2622 |
PLK1,RAB1A,GOLGA2,UBE2C,PTEN,GORASP1,MAD2L2,RPL11,FBXO5 |
| 2.198e-03 | -6.12 | negative regulation of nucleocytoplasmic transport | biological process | GO:0046823 | 21 | 9 | 17256 | 2622 |
CDK5,TXN,SP100,RAB23,RANGAP1,NUP153,MDFIC,PARK7,CHP1 |
| 2.200e-03 | -6.12 | membrane invagination | biological process | GO:0010324 | 50 | 16 | 17256 | 2622 |
RHOG,CHMP2A,RHOA,RAC1,MYH9,AURKB,BECN1,SCARB2,HGS,CHMP4A,CDC42,ELMO1,SNX18,SH3BP1,SMURF1,ABCA1 |
| 2.200e-03 | -6.12 | DLAT (dihydrolipoamide S-acetyltransferase) | protein interactions | 1737 | 43 | 15 | 17029 | 2761 |
SDHB,COX5B,PDK2,PRKD3,MDM2,SYNCRIP,PPT1,CS,CUL1,CYC1,ADRB2,OGDH,LMAN1,PDHX,NDUFS4 |
| 2.200e-03 | -6.12 | DPF3 (double PHD fingers 3) | protein interactions | 8110 | 43 | 15 | 17029 | 2761 |
SNRNP200,ARID2,AHSA1,BCL7C,BRD7,SMARCA4,CSNK2A1,SS18L1,ARID1A,PBRM1,TECR,SMARCE1,ARID1B,TIMM50,SMARCD1 |
| 2.200e-03 | -6.12 | TEX264 (testis expressed 264) | protein interactions | 51368 | 43 | 15 | 17029 | 2761 |
MCM10,FOXK1,OSBPL8,ABCC10,MAP4K4,STAT1,TMEM216,UPK3BL1,CHEK2,CSNK1A1,PDE3B,SNX14,CSNK1D,TYW1B,TERF2 |
| 2.200e-03 | -6.12 | EIF3M (eukaryotic translation initiation factor 3 subunit M) | protein interactions | 10480 | 43 | 15 | 17029 | 2761 |
EIF3K,RPN1,EIF3L,CYLD,GPBP1L1,HUWE1,EIF3D,BRCA1,AHCYL1,EIF1B,APP,EIF3G,EIF3H,EIF3A,USP34 |
| 2.200e-03 | -6.12 | BRD2 (bromodomain containing 2) | protein interactions | 6046 | 43 | 15 | 17029 | 2761 |
RB1,PWWP2B,BRD4,BRD2,E2F1,BRD7,COX5A,CSNK2A1,NSD3,TAGLN2,RUVBL2,E2F2,PIP4K2A,TERF2,CDC5L |
| 2.200e-03 | -6.12 | SP3 (Sp3 transcription factor) | protein interactions | 6670 | 43 | 15 | 17029 | 2761 |
TFAP4,RB1,DEAF1,SUB1,GABPA,MECP2,E2F1,YY1,B4GALT4,UBE2I,RBBP4,DNMT1,SENP1,HDAC2,PTPRK |
| 2.201e-03 | -6.12 | nucleotide-excision repair, DNA incision, 5'-to lesion | biological process | GO:0006296 | 37 | 13 | 17256 | 2622 |
RPA2,ERCC1,RFC3,PCNA,RBX1,POLK,RPS27A,XPA,CHD1L,RFC2,GTF2H2,DDB1,RPA1 |
| 2.201e-03 | -6.12 | neuron apoptotic process | biological process | GO:0051402 | 37 | 13 | 17256 | 2622 |
CDK5,RB1,MAX,PIGT,SIAH1,AKT2,OXR1,BCL2,BCL2L1,PSEN1,APP,USP53,FADD |
| 2.205e-03 | -6.12 | PID_NCADHERIN_PATHWAY | MSigDB lists | PID_NCADHERIN_PATHWAY | 33 | 12 | 17377 | 2626 |
KIF5B,MAPRE1,RHOA,CDC42,AXIN1,RAC1,PTPN11,LRP5,ROCK1,CAMK2G,PIP5K1C,DCTN1 |
| 2.205e-03 | -6.12 | BIOCARTA_DEATH_PATHWAY | MSigDB lists | BIOCARTA_DEATH_PATHWAY | 33 | 12 | 17377 | 2626 |
BIRC3,CASP6,XIAP,BCL2,CYCS,GAS2,MAP3K14,BIRC2,FADD,LMNA,SPTAN1,CFLAR |
| 2.205e-03 | -6.12 | DUTTA_APOPTOSIS_VIA_NFKB | MSigDB lists | DUTTA_APOPTOSIS_VIA_NFKB | 33 | 12 | 17377 | 2626 |
MDM2,CYLD,TNFAIP3,BIRC3,BIRC5,GADD45B,XIAP,BCL2,BCL2L1,BIRC2,CFLAR,FAS |
| 2.206e-03 | -6.12 | rRNA_MeTrfase_FtsJ_dom | interpro domains | IPR002877 | 5 | 4 | 18492 | 2768 |
CMTR2,FTSJ3,FTSJ1,MRM2 |
| 2.220e-03 | -6.11 | endometrium-carcinoma-adenocarcinoma | COSMIC cancer mutations | endometrium-carcinoma-adenocarcinoma | 51 | 16 | 17385 | 2587 |
NRAS,VHL,SF3B1,KRAS,CDKN2C,GNAS,RB1,FGFR3,PTEN,PTPN11,MSH2,STK11,HRAS,SMAD4,MSH6,CDKN2A |
| 2.220e-03 | -6.11 | regulation of catalytic activity | biological process | GO:0050790 | 2299 | 396 | 17256 | 2622 |
FGFR1OP,TXN,TSC2,MAP3K7CL,XIAP,PLXNA1,CCNL2,CCNB1,UBE2I,PPP1R16B,RIC1,ELMOD2,PARK7,CALM2,CDK5,CDKN2C,PSMD1,ASAP2,RABGAP1L,RAB4A,DNM2,CRY2,FNIP2,CDC25B,SENP1,MLST8,BAK1,AKT2,ARHGAP45,MRNIP,TOPORS,AURKB,DCUN1D5,MCM2,RFC2,ARF4,PLEKHF2,KRIT1,MAP3K4,HHEX,WAS,MID1IP1,RPS27A,LIMK1,AXIN1,PRDX5,ITGB1,ARRB2,OAZ1,PDCD4,HSPH1,CLSPN,GMFG,MUT,CHTF18,RHOC,GADD45G,VAV2,PRKAA1,DHX9,ACAP1,CYCS,APH1B,PARN,PSEN1,VPS25,CFLAR,RTKN,DDRGK1,TFAP4,FKBP1A,SNX18,FBXO7,PPP4R1,MSH2,DAPK1,PIK3IP1,MVP,GNAI2,PPP6R1,TMED2,TERF2,SOCS5,MAPKAPK3,GTPBP4,ADRB2,CYFIP2,MAP2K2,FAS,XRCC5,SCARB2,HSPBP1,FNTA,GOLGA2,DUSP3,CSK,QARS,ARAP1,CABIN1,NDE1,PPP6R3,MAP3K5,ALS2,CDKN2A,EGLN1,RHOG,ANKRD27,KARS,PPP1R37,GGNBP2,NQO1,TRIP10,RPS6KA1,CAST,RAF1,PTTG1,MAGED1,WDTC1,TPX2,TBC1D13,DAZAP2,PRKACA,APP,CRKL,APLP2,SHC1,SH3BP1,RALB,TBC1D22A,TBC1D14,UCHL5,ADCY9,SOCS6,NSFL1C,CDKN1B,CDK12,TMBIM1,ADCY7,ANKLE2,CCT2,SHOC2,PSRC1,RFC3,MAP4K4,TAOK1,ELP4,PKMYT1,DNAJA1,RAB1A,PSMB9,SOCS7,PPP2CA,PPP2R5A,CORO1C,RPLP1,PITRM1,XRCC4,LRP8,LRCH1,RPS2,PKP4,DEPDC1,ZFP91,AKT1S1,BLM,SPR,MAD2L2,GTF2F1,PPP1R3B,MAT2B,CCNK,PSMD2,PDCD10,PTEN,AHSA1,PPP1R8,ARHGEF1,PTPN11,AXIN2,DCP1A,ANXA5,FEM1B,MAP3K14,MSH6,PDPK1,TNFAIP3,DENND1B,NEK7,NET1,JTB,PARP4,MTMR12,MARK2,PICALM,FADD,SMAP2,SH3BP5,HGS,GPS2,PRDX3,OAZ2,PML,PPP1R11,HMGB2,PSAP,WDR91,CD81,IGBP1,CPEB2,FAF1,CCNC,PLXNC1,AGRN,NF1,PPP1R15B,ENSA,DNAJC24,CSNK2A1,AGFG1,S1PR2,MAPK14,BECN1,BIRC2,GIT2,ZER1,PRNP,ABL2,PCNA,RAP1A,THADA,PIK3R2,PPP1R12C,RP2,TCEA1,EIF5,CDC37,PLK1,COPS8,LARS,NCK1,APH1A,GMFB,CDC6,ARHGDIB,UBE2V1,LRP5,PRKRA,PRPSAP1,TBC1D17,SOCS4,MIA2,CAB39,ADAM9,STK11,CLU,ROCK1,DVL1,CLN3,POT1,CAPN1,TBC1D12,ZCCHC9,PPP1R2,PPP1R12A,GORASP1,DNAJB2,UBXN1,LAMTOR3,CIB1,RACGAP1,DNAJB1,RGS2,DOCK11,RAPGEF6,APOPT1,RB1,NUS1,TIGAR,RINL,ARL6IP1,BCL2,MDFIC,MCPH1,PREB,ATP5IF1,LDB1,GBA,KRAS,MAP4K3,ARHGAP15,CAND1,MASTL,MBIP,TSC1,SIAH2,NLRC5,NUP62,CTSA,MYO9A,SNRNP70,NIPSNAP2,BCCIP,PRKAB1,TRAF7,IFI27L1,DYNLL1,TOR1AIP1,LYN,DUSP22,BCAP31,RPL11,HNRNPA2B1,VAV1,UBXN2A,MDM2,TNFAIP8,NVL,PIN1,PPME1,KIF14,PDCD2,CHTOP,F2R,ABI1,GM2A,HTRA2,DVL2,DNAL4,CHP1,PPIF,ARHGAP17,TIMP2,BIRC3,PPT1,DNAJC9,TOR1AIP2,AFDN,DNAJC10,TAB2,RBL1,HNRNPR,UBXN2B,STK38,PSMD3,GADD45B,ANP32E,SCARB1,CCDC125,MAPK1,PPP2R2D,MIF,BCL2L12,DNAJC2,GCLM,SMAP1,DAP,DBF4,MYO9B,DCUN1D4,RGS1,FBXO5,PTPN2,FGFR3,TANK,DUS2,NABP2,H2AFY,ATG13,PTGES3,STAT3,TGFB1,TELO2,PPP1R9B,ADAM17,RHOA,HMGN1,PRKAR1B,RFFL,ARHGEF12,RANGAP1,WDR81,MEN1,MAPK3,NEK1,PDCD6,PLAA,BIRC5,OSBPL8,PKD2,NR2F2,ARHGAP23,UBE2C,HRAS,TERF1,HIPK3,IFI16 |
| 2.221e-03 | -6.11 | ATP biosynthetic process | biological process | GO:0006754 | 73 | 21 | 17256 | 2622 |
TGFB1,GALK1,COX5B,LDHA,ATP6V0A1,OGDH,ATP5F1B,ADPGK,PKM,ATP5MF,ATP5PF,STOML2,ATP5MC3,ATP6V0A2,DHTKD1,CYC1,ATP5F1A,GPI,NIPSNAP2,PGAM1,PFKP |
| 2.221e-03 | -6.11 | SCF-dependent proteasomal ubiquitin-dependent protein catabolic process | biological process | GO:0031146 | 73 | 21 | 17256 | 2622 |
RBX1,PSMA8,PSMB7,CUL1,FBXO9,PSMA1,CCNF,PSMD9,PSMB9,PSMB3,PSMC4,PSMD2,PSMD1,PSMA6,RPS27A,PSMD8,KIF14,PSMD3,FBXL7,FBXL3,PSMC1 |
| 2.231e-03 | -6.11 | Advanced glycosylation endproduct receptor signaling | REACTOME pathways | R-HSA-879415 | 13 | 7 | 10287 | 1696 |
CAPZA2,DDOST,MAPK1,PRKCSH,APP,MAPK3,CAPZA1 |
| 2.231e-03 | -6.11 | CLEC7A (Dectin-1) induces NFAT activation | REACTOME pathways | R-HSA-5607763 | 13 | 7 | 10287 | 1696 |
CALM2,NFATC2,PPP3CA,NFATC3,PPP3CB,AHCYL1,PPP3R1 |
| 2.231e-03 | -6.11 | GO_PROTEIN_METHYLTRANSFERASE_ACTIVITY | MSigDB lists | GO_PROTEIN_METHYLTRANSFERASE_ACTIVITY | 64 | 19 | 17377 | 2626 |
ASH1L,HEMK1,SUZ12,CXXC1,EHMT1,WDR82,EZH1,MEN1,ICMT,WDR5,PRMT2,DOT1L,IRF4,SUV39H2,SETD3,CAMKMT,PRMT7,FBL,CARM1 |
| 2.231e-03 | -6.11 | REACTOME_SEMAPHORIN_INTERACTIONS | MSigDB lists | REACTOME_SEMAPHORIN_INTERACTIONS | 64 | 19 | 17377 | 2626 |
RHOG,RHOA,PLXNC1,RHOC,RAC1,MYH9,ARHGEF12,PLXNA1,RHOB,PIP5K1C,DPYSL3,CDK5,CDC42,DPYSL2,LIMK1,ITGB1,ROCK1,MYL12B,CFL1 |
| 2.233e-03 | -6.10 | UBAC2 (UBA domain containing 2) | protein interactions | 337867 | 60 | 19 | 17029 | 2761 |
CLPTM1,ERLIN1,PRKDC,RAB7A,KRAS,SYVN1,TOMM40,VDAC1,STK17B,TMEM201,NPLOC4,CAND1,TBC1D17,SURF4,RAB35,RPN2,ATP6V1C1,LRRC59,HNRNPM |
| 2.233e-03 | -6.10 | ELOA (elongin A) | protein interactions | 6924 | 60 | 19 | 17029 | 2761 |
POLR2I,POLR2G,POLR2L,POLR2K,VHL,CUL3,POLR2D,GMCL1,BRCA1,PSMB9,POLR2A,LMNA,RAD54B,CHAF1A,RAP1A,POLR2J,CTR9,YWHAZ,CDK12 |
| 2.241e-03 | -6.10 | GO_REGULATION_OF_PROTEIN_LOCALIZATION_TO_NUCLEUS | MSigDB lists | GO_REGULATION_OF_PROTEIN_LOCALIZATION_TO_NUCLEUS | 212 | 48 | 17377 | 2626 |
DDX58,CYLD,TXN,CHERP,NF1,NUP54,RAB23,PPP3CB,MAPK14,PARK7,LMNA,PIN1,PIK3R2,SRI,AXIN2,FAM89B,GTSE1,MDFIC,MAVS,OGG1,HNRNPM,TGFB1,PLK1,CCT2,PPP3CA,RHOA,TRIM8,KAT7,BRCA1,NUTF2,CCT8,TRIM28,PRDX1,AKAP1,KEAP1,KPNA1,TONSL,AXIN1,OGT,PPP3R1,NUP62,PKD2,STK11,ZNF268,PARP10,SMAD4,CDKN2A,FAF1 |
| 2.242e-03 | -6.10 | ribonucleoprotein granule | cellular component | GO:0035770 | 205 | 46 | 18223 | 2701 |
SARNP,RAC1,HABP4,AGO2,PMS2,DHX9,TIA1,PCBP1,RBM4,PABPC4,CNOT3,EDC3,PSMA6,CDC42,GRSF1,DCP1A,UPF2,TAF5L,YBX1,CHTOP,PABPC1,SAMD4B,STAU1,DDX28,POLR2G,EID1,NSUN2,RPL6,POLR2D,CIRBP,FXR1,SYMPK,PATL1,BTBD1,CNOT9,UPF1,EIF4ENIF1,LSM6,ARNTL,ATXN2L,PQBP1,KHSRP,ACTB,SNRPG,ROCK1,TUBB |
| 2.248e-03 | -6.10 | ATP5MF (ATP synthase membrane subunit f) | protein interactions | 9551 | 39 | 14 | 17029 | 2761 |
MRPL50,COX15,PML,RPLP1,NDUFB9,NDUFA4,PRPF4,ATP5F1B,CNTROB,ATP5F1A,MCM2,VDAC1,ATP5PF,CCDC137 |
| 2.248e-03 | -6.10 | BMP2K (BMP2 inducible kinase) | protein interactions | 55589 | 39 | 14 | 17029 | 2761 |
MYO18A,GBA,GTSE1,MYH9,CAPZA2,CLTB,ANLN,CDK2,SEC16A,AP2S1,PICALM,TERF1,REPS1,TERF2 |
| 2.248e-03 | -6.10 | SENP2 (SUMO specific peptidase 2) | protein interactions | 59343 | 39 | 14 | 17029 | 2761 |
KPNA1,AGTRAP,HIPK2,AXIN1,SUMO2,CDCA5,PML,NUP107,ARL6IP1,TMEM216,RANGAP1,NUP153,APP,LMNA |
| 2.248e-03 | -6.10 | TCF7L2 (transcription factor 7 like 2) | protein interactions | 6934 | 39 | 14 | 17029 | 2761 |
KMT5A,RAC1,PML,XIAP,UHRF2,CSNK2A1,FUS,UBE2I,MEN1,DAZAP2,PSEN1,CDC73,MAD2L2,XRCC5 |
| 2.248e-03 | -6.10 | RHOT2 (ras homolog family member T2) | protein interactions | 89941 | 39 | 14 | 17029 | 2761 |
RPS2,NDUFS1,EIF4A3,HNRNPR,BTAF1,DHX9,HNRNPF,NDUFS8,SRSF5,TECR,RHOT1,RPS26,XPR1,NDUFS7 |
| 2.248e-03 | -6.10 | NUP188 (nucleoporin 188) | protein interactions | 23511 | 39 | 14 | 17029 | 2761 |
CSDE1,RAE1,NUP107,RPS24,PTP4A3,TGOLN2,NUP153,USP48,KCMF1,NUP58,IFI16,SEH1L,NDUFS4,SPTAN1 |
| 2.249e-03 | -6.10 | REACTOME_ACTIVATED_NOTCH1_TRANSMITS_SIGNAL_TO_THE_NUCLEUS | MSigDB lists | REACTOME_ACTIVATED_NOTCH1_TRANSMITS_SIGNAL_TO_THE_NUCLEUS | 25 | 10 | 17377 | 2626 |
MIB2,ADAM17,ADAM10,APH1A,RPS27A,DTX4,ARRB2,APH1B,PSEN1,NUMB |
| 2.249e-03 | -6.10 | GO_REGULATION_OF_TRANSCRIPTION_INVOLVED_IN_G1_S_TRANSITION_OF_MITOTIC_CELL_CYCLE | MSigDB lists | GO_REGULATION_OF_TRANSCRIPTION_INVOLVED_IN_G1_S_TRANSITION_OF_MITOTIC_CELL_CYCLE | 25 | 10 | 17377 | 2626 |
RB1,PCNA,BRD4,E2F4,CDT1,E2F1,RRM2,CDC6,ORC1,FBXO5 |
| 2.249e-03 | -6.10 | REACTOME_TRANSFERRIN_ENDOCYTOSIS_AND_RECYCLING | MSigDB lists | REACTOME_TRANSFERRIN_ENDOCYTOSIS_AND_RECYCLING | 25 | 10 | 17377 | 2626 |
ATP6V0B,ATP6V1D,ATP6V0A2,ATP6V0C,ATP6V1B2,ATP6V1C1,ATP6V0E1,ATP6V0D1,TFRC,ATP6V1G1 |
| 2.251e-03 | -6.10 | FRA10AC1 (FRA10A associated CGG repeat 1) | protein interactions | 118924 | 35 | 13 | 17029 | 2761 |
TRIM41,ZCCHC10,THOC1,CHERP,CWC27,MFAP1,HABP4,PRPF3,ZNF830,GLRX3,EEF1D,VPS29,SF3B2 |
| 2.251e-03 | -6.10 | ELL (elongation factor for RNA polymerase II) | protein interactions | 8178 | 35 | 13 | 17029 | 2761 |
ZHX1,HUWE1,ASPM,DYNLL1,CTR9,SIKE1,ICE2,SIRT2,EAF2,MCM2,PIP4K2A,FGFR1OP2,POLR2A |
| 2.251e-03 | -6.10 | CKS2 (CDC28 protein kinase regulatory subunit 2) | protein interactions | 1164 | 35 | 13 | 17029 | 2761 |
CCNA2,DUT,CDT1,CDKN1B,PKMYT1,CCNB1,CDK2,CCNB2,ZADH2,ESPL1,CFL1,LDHB,CDC37 |
| 2.251e-03 | -6.10 | NUDCD1 (NudC domain containing 1) | protein interactions | 84955 | 35 | 13 | 17029 | 2761 |
PLD3,PDCD10,COPA,DHX16,ABCF2,UBA5,COPE,GBA,DHX8,COPG2,DHX15,USP36,COPB2 |
| 2.251e-03 | -6.10 | KMT2D (lysine methyltransferase 2D) | protein interactions | 8085 | 35 | 13 | 17029 | 2761 |
MAX,CXXC1,PPP1R21,E2F3,WDR82,CHEK2,MEF2D,SMAD1,MEN1,WDR5,E2F2,EYA2,POLR2A |
| 2.251e-03 | -6.10 | Cul1 (cullin 1) | protein interactions | 26965 | 35 | 13 | 17029 | 2761 |
MKNK1,FOXM1,RBX1,FBXO7,IARS2,CDCA3,NUP54,LTN1,TTC3,USP11,CPEB2,ZC3HC1,CAND1 |
| 2.264e-03 | -6.09 | GSE14769_UNSTIM_VS_60MIN_LPS_BMDM_UP | MSigDB lists | GSE14769_UNSTIM_VS_60MIN_LPS_BMDM_UP | 180 | 42 | 17377 | 2626 |
PPIB,PRKAB1,C19orf53,SYS1,PHF23,SEC61G,BABAM1,TRMT6,AP3M2,NHLRC3,EIF1B,TRIM65,FBXO5,CRKL,DNAJC8,MED8,NSRP1,PPIL2,FAM76B,NDUFA3,ZNF770,POLR2D,MRPL43,BCLAF1,RIT1,MCFD2,BORA,BTBD1,DDX17,SDHB,HHEX,CDC16,TIMM13,FBXO41,AGPAT2,WNT5B,MRPL27,NDUFA11,COX8A,ZFP90,DUSP11,DYNC1LI2 |
| 2.264e-03 | -6.09 | GSE35825_IFNA_VS_IFNG_STIM_MACROPHAGE_DN | MSigDB lists | GSE35825_IFNA_VS_IFNG_STIM_MACROPHAGE_DN | 180 | 42 | 17377 | 2626 |
SEPHS2,RMND5A,TCF12,NOP2,CASP6,MANBA,RPS6KA1,GNE,UCK2,MRPS26,ADPGK,ZNRF3,EEF2K,CDKN2C,NFATC3,PPP1R8,PIK3R2,XPA,AKAP8,PPP1R12C,NUP153,DNMT1,PACS2,CARS2,ANKLE2,RB1CC1,PPT1,SNX2,NET1,DENND1B,POLR3GL,STK17B,CBX3,AKAP1,PTPRF,PCM1,TXNDC16,SCAP,OGT,LTA4H,ZMAT3,NUDT3 |
| 2.264e-03 | -6.09 | GSE6674_ANTI_IGM_VS_CPG_STIM_BCELL_UP | MSigDB lists | GSE6674_ANTI_IGM_VS_CPG_STIM_BCELL_UP | 180 | 42 | 17377 | 2626 |
HECA,TSC22D3,CDCA3,KIF2C,FOXO3,PIP4K2A,CCDC28A,PAIP2,MAT2B,NFATC3,ADD3,TTC9C,PIK3IP1,FRMD8,CTDSP2,CDKN2AIP,KIAA0040,ZNF512,OXR1,NARF,HSDL1,AURKB,PNPLA8,CCNF,PTTG1IP,ANKRD46,MASTL,FAS,NEK1,KIF18B,SLC38A7,L3MBTL3,UEVLD,STK38,OAZ2,ZNF436,SLAIN1,NGLY1,GLCCI1,TOB1,POT1,USP53 |
| 2.264e-03 | -6.09 | GSE14308_TH2_VS_NATURAL_TREG_UP | MSigDB lists | GSE14308_TH2_VS_NATURAL_TREG_UP | 180 | 42 | 17377 | 2626 |
SLC30A9,KARS,KIAA0100,FOXM1,PRKCSH,TMEM41B,TMX3,VTI1A,CHCHD2,JMJD6,ABCB10,PRKACA,MRPL19,PNO1,KIAA1147,USP5,UBXN2A,MDFIC,ATP6V0D1,MTX2,ZNF800,POC5,SNX25,BCLAF1,NUP155,RIT1,HAGH,TOLLIP,BBS12,POLE,ORMDL2,CCDC86,RAB24,HAGHL,PKD2,STK11,SPRYD4,NDE1,MZT2B,APOL2,BYSL,RAD51D |
| 2.264e-03 | -6.09 | GSE369_IFNG_KO_VS_WT_LIVER_UP | MSigDB lists | GSE369_IFNG_KO_VS_WT_LIVER_UP | 180 | 42 | 17377 | 2626 |
MBD1,PNISR,GMFG,HJURP,UBR2,CENPF,ACAP1,TIA1,EZH1,ZNF518A,ELMOD2,GIT2,PAIP2,CFLAR,C2orf68,CDKN2C,ZCCHC2,FAM76B,CREB1,NCOA2,RNF169,MOB4,CYTH1,TNFAIP3,PARP4,FRAT2,DCLRE1C,ANLN,SHCBP1,ZFAND5,PDE3B,STX16,SGSH,JAK1,OAZ2,OGT,CNOT6,SLAIN1,MBD6,TFDP2,HIPK3,SNAPIN |
| 2.265e-03 | -6.09 | GO_PROTEIN_MODIFICATION_BY_SMALL_PROTEIN_REMOVAL | MSigDB lists | GO_PROTEIN_MODIFICATION_BY_SMALL_PROTEIN_REMOVAL | 133 | 33 | 17377 | 2626 |
OTUD5,USP7,CYLD,ATXN3,BABAM1,FAM76A,USP39,USP48,WDR48,USP5,UCHL5,JOSD1,COPS7B,FAM76B,ZRANB1,SENP1,USP34,COPS8,KAT2A,TNFAIP3,USP42,USP10,USP22,OTUD3,USP21,USP36,USP32,USP20,VCPIP1,COPS6,USP11,USP53,USP13 |
| 2.267e-03 | -6.09 | GNF2_CBFB | MSigDB lists | GNF2_CBFB | 29 | 11 | 17377 | 2626 |
MAPRE1,POLR2G,CSK,RBMX,EIF3D,MFNG,HNRNPF,PSMA1,RBM15,CBFB,IFI16 |
| 2.267e-03 | -6.09 | GO_DNA_REPLICATION_INITIATION | MSigDB lists | GO_DNA_REPLICATION_INITIATION | 29 | 11 | 17377 | 2626 |
POLA2,MCM10,POLE,PRIM2,MCM5,CDC6,ORC1,MCM2,PURA,GINS4,PRIM1 |
| 2.267e-03 | -6.09 | REACTOME_SEMA4D_IN_SEMAPHORIN_SIGNALING | MSigDB lists | REACTOME_SEMA4D_IN_SEMAPHORIN_SIGNALING | 29 | 11 | 17377 | 2626 |
RHOG,RHOA,CDC42,LIMK1,RHOC,RAC1,MYH9,ARHGEF12,ROCK1,MYL12B,RHOB |
| 2.267e-03 | -6.09 | KEGG_RNA_POLYMERASE | MSigDB lists | KEGG_RNA_POLYMERASE | 29 | 11 | 17377 | 2626 |
POLR2I,POLR2G,POLR2L,POLR2J,POLR2K,POLR2D,POLR3GL,POLR1B,ZNRD1,POLR3K,POLR2A |
| 2.268e-03 | -6.09 | KARLSSON_TGFB1_TARGETS_DN | MSigDB lists | KARLSSON_TGFB1_TARGETS_DN | 196 | 45 | 17377 | 2626 |
DNMT3A,ADAM10,MAGED1,ADO,XIAP,SIKE1,MAN2B1,CCNL2,MXD4,SLC12A9,STMN1,PAIP2,MAT2B,CDKN2C,GOLM1,PCNA,ADD3,FUT8,SLC44A1,TECR,SPTSSA,STAT3,CTDSP2,ENPP4,ZNF780B,NET1,DENND4C,DCAF8,WBP2,EZR,DNAJA1,AZI2,LY6E,H2AFV,POLR2A,HMGN2,PTPRF,TWSG1,BBX,DBI,APPL2,ACBD4,SLC16A1,CTSA,S100PBP |
| 2.272e-03 | -6.09 | Wnt Signaling Pathway Netpath | WikiPathways | WP363 | 53 | 17 | 5312 | 837 |
TSC1,RHOA,TSC2,CSNK1G1,AXIN1,TCF3,RAC1,AXIN2,NFATC2,LRP5,DVL1,CSNK1A1,MAPK1,ARRB2,CSNK1D,DVL2,PI4K2A |
| 2.275e-03 | -6.09 | oxidoreductase activity, acting on NAD(P)H | molecular function | GO:0016651 | 106 | 28 | 17224 | 2647 |
TXNL1,NDUFA5,COX15,NDUFV2,NDUFS1,TXN,NQO1,NDUFB6,NDUFAF2,NQO2,NARF,NDUFA4,NDUFA7,NDUFB1,NDUFS7,NDUFS4,DECR1,NDUFV1,NDUFA2,NDUFB4,PRDX3,CYB5RL,NDUFB9,NDUFS8,CYB5R1,NDUFS5,NDUFA3,RNLS |
| 2.284e-03 | -6.08 | GO_COATED_VESICLE | MSigDB lists | GO_COATED_VESICLE | 223 | 50 | 17377 | 2626 |
RAB14,TMED7,DNAJC5,COPA,HLA-E,SCYL1,COPE,VTI1A,TGOLN2,TMED3,ARF1,AP1B1,GGA2,SYNRG,SCYL2,COPG2,APP,BCAP31,HLA-A,COPB2,CD59,RAB8A,SNX18,RAB35,SEC24C,AP1M1,DNM2,AP2B1,LMAN1,CLTB,DVL2,TMED2,KDELR1,USO1,DENND1B,GOPC,PACS1,MCFD2,PICALM,NECAP2,SEC31A,HLA-B,SEC23IP,GOLGA2,TMED10,SCAP,AP1S1,DVL1,AP2S1,NUMB |
| 2.286e-03 | -6.08 | GSE34156_UNTREATED_VS_6H_NOD2_LIGAND_TREATED_MONOCYTE_UP | MSigDB lists | GSE34156_UNTREATED_VS_6H_NOD2_LIGAND_TREATED_MONOCYTE_UP | 159 | 38 | 17377 | 2626 |
GCLM,NAT9,NADSYN1,RAE1,SLC29A1,LYN,SLC25A37,GSTK1,LRRC8D,RRBP1,NDUFB9,TALDO1,TOP1MT,CNPY3,LPCAT1,TMBIM1,ATP6V1G1,TGFB1,CCDC57,UBQLN4,NUDT8,SEPT9,POLR2G,TNFAIP3,RFFL,MTX1,NDUFA7,GUF1,TOLLIP,MAP2K2,PRDX1,IRF5,PDLIM1,TULP3,LIMK1,SAMD8,CD81,GEMIN7 |
| 2.297e-03 | -6.08 | GO_POLYAMINE_METABOLIC_PROCESS | MSigDB lists | GO_POLYAMINE_METABOLIC_PROCESS | 14 | 7 | 17377 | 2626 |
SRM,DHPS,ODC1,SAT2,OAZ1,OAZ2,AMD1 |
| 2.297e-03 | -6.08 | MUELLER_COMMON_TARGETS_OF_AML_FUSIONS_UP | MSigDB lists | MUELLER_COMMON_TARGETS_OF_AML_FUSIONS_UP | 14 | 7 | 17377 | 2626 |
SOX4,CCNF,CITED2,SCAP,ARF5,TCF3,DNM2 |
| 2.297e-03 | -6.08 | GO_REGULATION_OF_SISTER_CHROMATID_COHESION | MSigDB lists | GO_REGULATION_OF_SISTER_CHROMATID_COHESION | 14 | 7 | 17377 | 2626 |
CTCF,H2AFY,RB1,ESPL1,NSMCE2,CDCA5,AXIN2 |
| 2.297e-03 | -6.08 | GO_NUCLEAR_PORE_ORGANIZATION | MSigDB lists | GO_NUCLEAR_PORE_ORGANIZATION | 14 | 7 | 17377 | 2626 |
NUP153,AHCTF1,NUP205,SEH1L,NUP107,TMEM33,NUP54 |
| 2.297e-03 | -6.08 | GO_CYTOPLASMIC_TRANSLATIONAL_INITIATION | MSigDB lists | GO_CYTOPLASMIC_TRANSLATIONAL_INITIATION | 14 | 7 | 17377 | 2626 |
CDC123,RBM4,EIF3D,EIF2D,PCBP2,EIF3A,MCTS1 |
| 2.297e-03 | -6.08 | REACTOME_SOS_MEDIATED_SIGNALLING | MSigDB lists | REACTOME_SOS_MEDIATED_SIGNALLING | 14 | 7 | 17377 | 2626 |
KRAS,NRAS,MAPK1,HRAS,RAF1,MAP2K2,MAPK3 |
| 2.297e-03 | -6.08 | REACTOME_N_GLYCAN_ANTENNAE_ELONGATION | MSigDB lists | REACTOME_N_GLYCAN_ANTENNAE_ELONGATION | 14 | 7 | 17377 | 2626 |
B4GALT1,B4GALT3,B4GALT4,ST8SIA2,B4GALT5,MGAT5,B4GALT2 |
| 2.300e-03 | -6.07 | WATANABE_RECTAL_CANCER_RADIOTHERAPY_RESPONSIVE_DN | MSigDB lists | WATANABE_RECTAL_CANCER_RADIOTHERAPY_RESPONSIVE_DN | 88 | 24 | 17377 | 2626 |
POU2AF1,RHOBTB3,NOP2,AGRN,PPP1R12A,KLF10,SNX2,ENSA,CUL1,GLUD1,TMEM147,SPR,AP3S1,LYN,CHD1,CFLAR,PPP2CA,PSMA6,CCDC6,AHSA1,MAP4,ITGB1,KHSRP,SCARB1 |
| 2.300e-03 | -6.07 | WINTER_HYPOXIA_UP | MSigDB lists | WINTER_HYPOXIA_UP | 88 | 24 | 17377 | 2626 |
MIF,ANKRD37,RHOC,SLC2A1,PSMB7,GMFB,RNPS1,LDHA,BMS1,MTX1,ANLN,METTL22,HAUS2,TPD52L2,PSMD2,HOMER1,CDCA4,CORO1C,PPP4R1,SLC16A1,RUVBL2,PGAM1,ANKRD9,B4GALT2 |
| 2.300e-03 | -6.07 | SIG_BCR_SIGNALING_PATHWAY | MSigDB lists | SIG_BCR_SIGNALING_PATHWAY | 46 | 15 | 17377 | 2626 |
PDPK1,VAV1,PPP3CA,SHC1,CSK,AKT2,RAF1,FLOT1,NFATC2,BCL2,PPP3CB,MAPK1,LYN,CD81,MAPK3 |
| 2.304e-03 | -6.07 | RING | smart domains | SM00184 | 240 | 51 | 9493 | 1367 |
MIB2,TRIM41,TRAF7,SHPRH,PHRF1,TRIM11,XIAP,BRAP,ZNRF3,TRIM65,BIRC2,ANKIB1,RNF103,RFWD3,RNF121,MEX3C,ZNRF2,RNFT1,TTC3,RNF19A,RNF135,RNF5,RNF169,RLIM,TRIM8,LONRF3,BIRC3,RNF25,PCGF6,RFFL,LNX2,TOPORS,SYVN1,BRCA1,KMT2C,PCGF1,TRIM28,TRIM4,TRIM47,COMMD3-BMI1,TRIM26,RAD18,DTX4,PML,RNF38,UHRF2,TRIM32,TRIM52,TRAF5,RNF139,RNF114 |
| 2.306e-03 | -6.07 | MRPS11 (mitochondrial ribosomal protein S11) | protein interactions | 64963 | 87 | 25 | 17029 | 2761 |
NOL12,RPS2,RPRD1A,MRPS2,MRPS15,NOA1,DRAP1,WDTC1,RPL6,MRPS26,CUL3,MRPS10,MRPS14,AFDN,DAP3,STRBP,HNRNPR,DDA1,MRPS27,TRMT10B,DUSP11,TCEA1,RPS26,ZC3H3,DCAF5 |
| 2.319e-03 | -6.07 | RPL39 (ribosomal protein L39) | protein interactions | 6170 | 20 | 9 | 17029 | 2761 |
HNRNPA2B1,RPS15,RBM3,RPL32,RPS9,PABPC1,FTSJ3,PABPC4,CDC5L |
| 2.319e-03 | -6.07 | Ranbp1 (RAN binding protein 1) | protein interactions | 19385 | 20 | 9 | 17029 | 2761 |
PGAP2,CCDC93,COMMD10,VPS26C,COMMD5,COMMD4,COMMD6,COMMD8,VPS29 |
| 2.319e-03 | -6.07 | ZNF133 (zinc finger protein 133) | protein interactions | 7692 | 20 | 9 | 17029 | 2761 |
PDPK1,FTL,DAP3,MDM2,MRPS2,RPS27A,MAPK6,MRS2,TRIM28 |
| 2.319e-03 | -6.07 | SLX4IP (SLX4 interacting protein) | protein interactions | 128710 | 20 | 9 | 17029 | 2761 |
PLK1,RPN1,ERCC1,GORASP1,SUMO2,CUL1,PAGR1,MAPK14,PDCD2L |
| 2.319e-03 | -6.07 | Prpf3 (pre-mRNA processing factor 3) | protein interactions | 70767 | 20 | 9 | 17029 | 2761 |
SART1,MRPS2,RPL38,ATXN2L,H2AFY,PRPF4,RFC2,PHF6,DDX23 |
| 2.319e-03 | -6.07 | MAPK13 (mitogen-activated protein kinase 13) | protein interactions | 5603 | 20 | 9 | 17029 | 2761 |
ANKLE2,MAP3K4,MAPKAPK3,ATF2,APP,SMAD4,HTRA2,EEF2K,GPX4 |
| 2.319e-03 | -6.07 | OSBPL11 (oxysterol binding protein like 11) | protein interactions | 114885 | 20 | 9 | 17029 | 2761 |
KLHL20,WDR44,TRIP10,TMEM216,DNAJA1,LYN,APP,CAND1,TERF2 |
| 2.319e-03 | -6.07 | RIT1 (Ras like without CAAX 1) | protein interactions | 6016 | 20 | 9 | 17029 | 2761 |
AFDN,IFRD1,LZTR1,SMAD2,VHL,RGL1,RLF,SMURF1,SRPK2 |
| 2.319e-03 | -6.07 | NUAK2 (NUAK family kinase 2) | protein interactions | 81788 | 20 | 9 | 17029 | 2761 |
USP7,LZTR1,SMAD2,PPP1R12A,PRKAA1,APP,MARK2,SMAD4,DCAF5 |
| 2.323e-03 | -6.06 | PID_IL2_1PATHWAY | MSigDB lists | PID_IL2_1PATHWAY | 55 | 17 | 17377 | 2626 |
RHOA,NRAS,RAF1,KRAS,MAPK14,STAM,MAP2K2,MAPK3,SHC1,JAK1,PTPN11,STAT1,BCL2,STAT3,MAPK1,CDK2,HRAS |
| 2.323e-03 | -6.06 | GO_APOPTOTIC_MITOCHONDRIAL_CHANGES | MSigDB lists | GO_APOPTOTIC_MITOCHONDRIAL_CHANGES | 55 | 17 | 17377 | 2626 |
MOAP1,BAK1,PPIF,GCLM,NDUFS1,ATG3,JTB,MCL1,BCL2,CLU,BCL2L1,RHOT1,ATF2,RHOT2,EYA2,CDKN2A,TIMM50 |
| 2.326e-03 | -6.06 | regulation of mitochondrial membrane permeability | biological process | GO:0046902 | 78 | 22 | 17256 | 2622 |
BAK1,PPIF,ATP5IF1,DYNLL1,HEBP2,BCL2L1,RHOT1,SLC25A5,RHOT2,MOAP1,TFDP1,PPP3R1,E2F1,BCL2,YWHAZ,TP53BP2,TFDP2,TMEM14A,ATF2,YWHAH,STAT3,EYA2 |
| 2.328e-03 | -6.06 | HDR through Homologous Recombination (HRR) | REACTOME pathways | R-HSA-5685942 | 68 | 21 | 10287 | 1696 |
RFC3,POLK,RAD51AP1,RMI2,TOP3A,BRCA1,BLM,RFC2,RMI1,RPA1,RPA2,RAD51C,PCNA,PALB2,POLE,RPS27A,XRCC2,XRCC3,GEN1,SPIDR,RAD51D |
| 2.333e-03 | -6.06 | MRPL13 (mitochondrial ribosomal protein L13) | protein interactions | 28998 | 69 | 21 | 17029 | 2761 |
PPAN,MRPL9,CYLD,NDUFS1,MRPL42,MRPL39,MRPL12,RPL6,MRPL16,OGDH,LYRM2,MRPL19,MRPL50,MRPL2,COQ4,MRPL55,MPV17,DUSP11,MRPL11,ZC3H3,MRPL3 |
| 2.337e-03 | -6.06 | positive regulation of maintenance of mitotic sister chromatid cohesion | biological process | GO:0034184 | 5 | 4 | 17256 | 2622 |
H2AFY,SLF1,NSMCE2,SLF2 |
| 2.337e-03 | -6.06 | viral translational termination-reinitiation | biological process | GO:0075525 | 5 | 4 | 17256 | 2622 |
EIF3L,EIF3G,EIF3D,EIF3A |
| 2.337e-03 | -6.06 | regulation of protein monoubiquitination | biological process | GO:1902525 | 5 | 4 | 17256 | 2622 |
PDCD6,PEF1,BIRC2,WDR48 |
| 2.337e-03 | -6.06 | positive regulation of maintenance of sister chromatid cohesion | biological process | GO:0034093 | 5 | 4 | 17256 | 2622 |
H2AFY,SLF1,NSMCE2,SLF2 |
| 2.337e-03 | -6.06 | positive regulation of exit from mitosis | biological process | GO:0031536 | 5 | 4 | 17256 | 2622 |
TGFB1,PHB2,UBE2C,CDCA5 |
| 2.340e-03 | -6.06 | GSE14308_NAIVE_CD4_TCELL_VS_INDUCED_TREG_UP | MSigDB lists | GSE14308_NAIVE_CD4_TCELL_VS_INDUCED_TREG_UP | 175 | 41 | 17377 | 2626 |
TCF12,PHF23,TOR1AIP1,MED13L,CHIC2,ETS1,C2orf68,ANKRD26,ARPC5,WDR44,CENPJ,FUT8,ARHGEF1,ARL5A,CCAR1,DRAM2,CGGBP1,TERF2,MORC3,PDPK1,ELOVL5,DPM1,SNX2,CIC,PGS1,RPL38,RTF1,PCGF1,FXR1,BTBD1,ANKRD10,MKNK1,CERS6,OSBPL8,RNASEL,IGBP1,ZBTB11,XRCC4,HEXA,CPEB2,TERF1 |
| 2.340e-03 | -6.06 | GSE7509_UNSTIM_VS_IFNA_STIM_IMMATURE_DC_UP | MSigDB lists | GSE7509_UNSTIM_VS_IFNA_STIM_IMMATURE_DC_UP | 175 | 41 | 17377 | 2626 |
H2AFZ,MCM10,DHPS,PHB2,NACA,DBF4,TPX2,CDCA3,RACGAP1,KIF2C,PMF1,FKBP2,WRB,MYL6B,SLC31A1,FJX1,SLC27A4,TECR,RNF26,LDLRAD3,TMED2,TIMM50,TACC1,NET1,MYBL2,MKI67,RPL38,CYP20A1,CKAP2L,AURKB,ANLN,SHCBP1,SF3A2,TMEM201,RPL37,KIF18B,TOMM6,E2F1,FAM83D,MBOAT1,BEND6 |
| 2.346e-03 | -6.06 | telomere maintenance via semi-conservative replication | biological process | GO:0032201 | 25 | 10 | 17256 | 2622 |
POLA2,RPA2,PCNA,RFC3,UPF1,PRIM2,POLE,RFC2,PRIM1,RPA1 |
| 2.346e-03 | -6.06 | other organism | cellular component | GO:0044215 | 75 | 21 | 18223 | 2701 |
NDC1,NUP188,RAE1,NUP54,NUP155,NUP205,NMT2,PI4K2A,KPNA4,NUP210,KPNA1,RPS27A,NUP107,NUP153,NUP62,KPNA2,LMAN1,NUP85,NUP58,AAAS,SEH1L |
| 2.346e-03 | -6.06 | other organism cell | cellular component | GO:0044216 | 75 | 21 | 18223 | 2701 |
NDC1,NUP188,RAE1,NUP54,NUP155,NMT2,NUP205,PI4K2A,NUP210,KPNA1,KPNA4,RPS27A,NUP107,NUP62,KPNA2,NUP153,LMAN1,NUP58,NUP85,AAAS,SEH1L |
| 2.346e-03 | -6.06 | other organism part | cellular component | GO:0044217 | 75 | 21 | 18223 | 2701 |
NDC1,NUP188,RAE1,NUP54,NUP155,NMT2,NUP205,PI4K2A,NUP210,KPNA1,KPNA4,RPS27A,NUP107,NUP62,KPNA2,NUP153,LMAN1,NUP58,NUP85,AAAS,SEH1L |
| 2.347e-03 | -6.05 | FLNB (filamin B) | protein interactions | 2317 | 101 | 28 | 17029 | 2761 |
TXNL1,SEPT9,GGA1,SUZ12,RAC1,DCTN2,MYH9,BRCA1,CAPZA2,AP1B1,ANLN,MCM2,PSEN1,CDC73,ISG15,NUP210,AHNAK,PTEN,MCM5,PSMD3,MAP4,MYO18A,ITGB1,TARDBP,CDK2,ARRB2,NMD3,HNRNPM |
| 2.347e-03 | -6.05 | VPS26A (VPS26, retromer complex component A) | protein interactions | 9559 | 101 | 28 | 17029 | 2761 |
MIF,UNK,ANKRD27,UBQLN4,SNX2,RAB7A,JMJD6,UBE4B,RUFY1,SYMPK,VPS25,RBM4,TARS,SAC3D1,ZER1,CYHR1,INTS7,VPS26B,CORO1C,STAT1,TTC4,AHCYL1,H3F3A,ECPAS,UTP4,SSSCA1,VPS29,NUDC |
| 2.350e-03 | -6.05 | GEMIN5 (gem nuclear organelle associated protein 5) | protein interactions | 25929 | 78 | 23 | 17029 | 2761 |
EWSR1,TXN,SNRPB,CUL3,DDX20,BRCA1,SNRPD3,GAR1,MAPK3,RPA1,RPA2,DECR1,GOLGA4,CENPJ,GEMIN6,CRY2,SNRPG,GEMIN4,MAP3K5,SNRNP70,STRAP,SSSCA1,GEMIN7 |
| 2.350e-03 | -6.05 | DAB1 (DAB1, reelin adaptor protein) | protein interactions | 1600 | 78 | 23 | 17029 | 2761 |
ZCCHC10,WDYHV1,SNRPB,MAGED1,ARID5A,DAZAP2,TOLLIP,ITGB5,APP,SMAP2,SOCS7,CRKL,CDK5,APLP2,SERF2,STRBP,SIAH1,PIN1,PPIG,SOCS6,PTPN11,USP53,LRP8 |
| 2.352e-03 | -6.05 | GSE2770_UNTREATED_VS_IL4_TREATED_ACT_CD4_TCELL_48H_UP | MSigDB lists | GSE2770_UNTREATED_VS_IL4_TREATED_ACT_CD4_TCELL_48H_UP | 191 | 44 | 17377 | 2626 |
MMACHC,NDUFB6,AGRN,ANXA6,MDH2,UFC1,GNE,FKBP2,SPR,GGPS1,APP,EEF2K,DDX56,NEK6,NDUFB4,PELO,NSFL1C,MRPL54,ALDH18A1,FAM3A,SGCB,PPA1,S100A6,IMPA2,PREB,EBAG9,POLR2I,DCAF6,ETV3,ATG9A,CREG1,SCFD2,ATXN1,EDF1,EAF2,APPL1,SLC50A1,ARF4,MKNK1,NSMCE2,LIMK1,CLU,SLC22A23,RTN3 |
| 2.352e-03 | -6.05 | GSE15330_MEGAKARYOCYTE_ERYTHROID_VS_GRANULOCYTE_MONOCYTE_PROGENITOR_DN | MSigDB lists | GSE15330_MEGAKARYOCYTE_ERYTHROID_VS_GRANULOCYTE_MONOCYTE_PROGENITOR_DN | 191 | 44 | 17377 | 2626 |
TMEM106C,PPIB,LZTR1,SMAP1,GNPDA1,SRGN,MAGED1,CENPF,TRAK1,AGPAT3,ABCB10,TMED3,RAB6A,GGA2,CMTM6,PRNP,RALB,GMEB1,AFF1,CABLES2,RNF26,RPRD1B,SPSB3,TMX1,ALDH9A1,SPTAN1,AMPD2,TIMP2,FAM49B,RNASEH2C,CDC6,ESYT1,KLF6,PLEKHF2,YIF1A,PPP2CA,RAB18,TAB2,FAM122A,ZFP90,FBXL3,HRAS,VPS29,SMARCD1 |
| 2.352e-03 | -6.05 | GSE39820_CTRL_VS_TGFBETA1_IL6_CD4_TCELL_UP | MSigDB lists | GSE39820_CTRL_VS_TGFBETA1_IL6_CD4_TCELL_UP | 191 | 44 | 17377 | 2626 |
PKP4,DNMT3A,CDC40,SARNP,PARP12,PLXNC1,MRPL39,HMGN3,PLXNA1,DOCK11,PITHD1,TFRC,RFWD3,RPA2,CTSS,RCSD1,ZCCHC2,PTPN11,SUCLG2,ANKRD13C,TARDBP,CENPM,CREB1,CNOT6L,C12orf75,DNMT1,SLC35A1,NCOA2,AMPD2,PPP3CA,WDHD1,SLBP,PHF6,TWISTNB,DTWD1,SLCO4A1,PTER,ITGB1,QRSL1,AEN,GAS2,CD81,PTDSS1,CBX4 |
| 2.355e-03 | -6.05 | Sema4D in semaphorin signaling | REACTOME pathways | R-HSA-400685 | 27 | 11 | 10287 | 1696 |
RHOG,RHOA,CDC42,LIMK1,RHOC,RAC1,MYH9,ARHGEF12,ROCK1,MYL12B,RHOB |
| 2.355e-03 | -6.05 | Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA) | REACTOME pathways | R-HSA-5693554 | 27 | 11 | 10287 | 1696 |
RAD51C,PALB2,RAD51AP1,XRCC2,RMI2,TOP3A,XRCC3,BRCA1,BLM,RMI1,RAD51D |
| 2.357e-03 | -6.05 | GO_LOCALIZATION_WITHIN_MEMBRANE | MSigDB lists | GO_LOCALIZATION_WITHIN_MEMBRANE | 118 | 30 | 17377 | 2626 |
USO1,TRAPPC9,AGRN,GORASP1,RAC1,CUL3,MCFD2,RAB1A,SEC16A,ANKRD28,CD59,SEC31A,CDK5,FNTA,SEC23IP,GOLGA2,NSF,TMED10,SEC24C,ITGB1,PPP6C,SSNA1,DVL1,PPP6R3,TFG,LMAN1,PPP6R1,CSNK1D,TMED2,PREB |
| 2.358e-03 | -6.05 | single-stranded RNA binding | molecular function | GO:0003727 | 82 | 23 | 17224 | 2647 |
DDX58,POLR2G,PPIE,AGO2,DHX9,HNRNPF,POLR2D,ATXN1,TIA1,JMJD6,LACTB2,FXR1,EIF4H,PATL1,PABPC4,SYNCRIP,MEX3C,STRBP,EIF4A3,RBMX,TRA2B,PABPC1,CBX4 |
| 2.371e-03 | -6.04 | GO_CARBOHYDRATE_METABOLIC_PROCESS | MSigDB lists | GO_CARBOHYDRATE_METABOLIC_PROCESS | 628 | 121 | 17377 | 2626 |
GLT8D1,UGP2,GXYLT1,GNPDA1,PRKCSH,PIGQ,MDH2,SLC2A1,HEXB,MOGS,WDTC1,SIRT2,ADPGK,GYG1,NANS,MAPK14,EXT2,EPM2A,CREM,CALM2,TET3,PDK2,USF1,GOT2,IMPAD1,IL6ST,CS,AKR1B1,RPN2,TALDO1,SLC35C2,LMAN1,TIPARP,GPD1L,MGAT5,GM2A,TMEM115,DPM1,AKT2,IDH3A,PFKFB3,LRP5,GLO1,GALK2,GALNT7,AMDHD2,OGDH,MCFD2,EDEM2,SERP1,ARF4,MAN2A2,ALG3,DDOST,UEVLD,STT3A,RPS27A,OGT,DHTKD1,ST3GAL2,GALNT10,B4GALT3,CHID1,PFKP,B4GALT2,GALK1,PPP1R2,GORASP1,B4GALT5,MANBA,MECP2,GNE,PRKAA1,TRAK1,TKT,SLC25A12,B4GALT1,SDF2L1,MAN2B1,B4GALT4,TMEM165,PSEN1,POFUT1,MAN1A1,PPP1R3B,C1GALT1,RPN1,NUS1,PTEN,DAD1,FUT8,OSTC,ST8SIA2,PHKG2,SLC35A1,IMPA2,SLC25A1,LDHB,NAGPA,B3GALT6,MLEC,GALC,MAN1B1,PARP4,LDHA,GBA,SYVN1,HAGH,NEU1,CYB5A,GALNT2,MAGT1,GOLGA2,PARG,CTBS,MDH1,GPI,NANP,HEXA,PGAM1,PARP10 |
| 2.373e-03 | -6.04 | interleukin-6-mediated signaling pathway | biological process | GO:0070102 | 14 | 7 | 17256 | 2622 |
CTR9,JAK1,STAT3,IL6ST,SMAD4,PTPN11,STAT1 |
| 2.373e-03 | -6.04 | cytoplasmic translational initiation | biological process | GO:0002183 | 14 | 7 | 17256 | 2622 |
EIF5,EIF4H,RBM4,EIF3D,EIF2D,EIF3A,MCTS1 |
| 2.374e-03 | -6.04 | OUILLETTE_CLL_13Q14_DELETION_UP | MSigDB lists | OUILLETTE_CLL_13Q14_DELETION_UP | 69 | 20 | 17377 | 2626 |
ADAM17,LONRF3,UBE2Q1,EAF2,RAB1A,RPAIN,SLC50A1,CYB5A,GINS4,FANCI,ATAD2,KLHL5,CDC27,CENPJ,WDR59,BBX,VCPIP1,ZNF226,RUFY3,MAPK1 |
| 2.374e-03 | -6.04 | MILI_PSEUDOPODIA_CHEMOTAXIS_UP | MSigDB lists | MILI_PSEUDOPODIA_CHEMOTAXIS_UP | 69 | 20 | 17377 | 2626 |
PKP4,GXYLT1,HMGN5,PGGT1B,PDAP1,CCDC34,EIF2A,SEPT7,MATR3,EIF3A,KIF5B,NAP1L1,EIF2S2,HSPB11,GOLGA4,NAA50,VCPIP1,GLTP,MTPN,DCAF5 |
| 2.380e-03 | -6.04 | MORF_RFC1 | MSigDB lists | MORF_RFC1 | 103 | 27 | 17377 | 2626 |
KDM3B,MLEC,NUP188,HMGN4,PRKCSH,IDH3A,LDB1,BMS1,LANCL1,ORC1,PKMYT1,SEPT7,PCGF1,TAZ,CDK11A,POLR2A,MFN2,TFAP4,RAP1A,DNAJC8,TPP2,NUP62,TCOF1,CPSF4,WDR62,B4GALT3,NUDT3 |
| 2.383e-03 | -6.04 | Amino sugar and nucleotide sugar metabolism | KEGG pathways | ko00520 | 48 | 16 | 7161 | 1149 |
GALK1,CMAS,UGP2,GNPNAT1,TSTA3,GNPDA1,GNE,HEXB,NANS,AMDHD2,UAP1,CYB5RL,GPI,CYB5R1,NANP,HEXA |
| 2.383e-03 | -6.04 | Amino sugar and nucleotide sugar metabolism | KEGG pathways | hsa00520 | 48 | 16 | 7161 | 1149 |
CMAS,GALK1,UGP2,GNPNAT1,TSTA3,GNPDA1,GNE,HEXB,NANS,AMDHD2,UAP1,CYB5RL,GPI,CYB5R1,NANP,HEXA |
| 2.383e-03 | -6.04 | proton-transporting ATPase activity, rotational mechanism | molecular function | GO:0046961 | 21 | 9 | 17224 | 2647 |
ATP6V0B,ATP6V0A1,ATP6V0A2,ATP6V0C,ATP5F1B,ATP6V1B2,ATP6V1C1,ATP6V0E1,ATP6V0D1 |
| 2.388e-03 | -6.04 | epithelioid | COSMIC cancer mutations | epithelioid | 38 | 13 | 17385 | 2587 |
TSC1,RB1,NRAS,PALB2,TSC2,NF1,PTEN,SF3B1,KRAS,FUS,SMAD4,HRAS,CDKN2A |
| 2.398e-03 | -6.03 | LPAR6 (lysophosphatidic acid receptor 6) | protein interactions | 10161 | 56 | 18 | 17029 | 2761 |
TMEM184B,MTX3,COG1,PXMP2,ARL5B,STK17B,PDXDC1,WRB,SFXN5,JAK1,VMP1,BDH1,LMBR1,TNPO2,ORAI1,FAM126A,KNTC1,GPR89B |
| 2.398e-03 | -6.03 | ACAA2 (acetyl-CoA acyltransferase 2) | protein interactions | 10449 | 56 | 18 | 17029 | 2761 |
EWSR1,H2AFZ,CSRP1,TKT,VDAC2,EZR,FKBP2,TOMM40,VDAC1,POFUT1,APP,PRDX1,ZFR,HNRNPA2B1,ACAT1,TAGLN2,PREPL,CFL1 |
| 2.404e-03 | -6.03 | ELONGATNFCT | prints domains | PR00315 | 15 | 6 | 4652 | 473 |
EFL1,GUF1,GFM2,GSPT2,EFTUD2,TUFM |
| 2.410e-03 | -6.03 | GO_POSITIVE_REGULATION_OF_WNT_SIGNALING_PATHWAY | MSigDB lists | GO_POSITIVE_REGULATION_OF_WNT_SIGNALING_PATHWAY | 149 | 36 | 17377 | 2626 |
ZBED3,XIAP,CSNK2A1,SMARCA4,PSMD9,CDC73,PSMD2,PSMD1,PSMA6,PIN1,MBD2,AXIN2,ZRANB1,DVL2,USP34,PSMA8,ASPM,PSMB7,PSMA1,SOX4,MACF1,PSMB9,PSMB3,DAPK3,PSMC4,HHEX,RPS27A,PSMD3,AXIN1,PSMD8,ARNTL,ATP6V0C,DVL1,RBPJ,PSMC1,CSNK1D |
| 2.410e-03 | -6.03 | GSE45365_NK_CELL_VS_CD8_TCELL_UP | MSigDB lists | GSE45365_NK_CELL_VS_CD8_TCELL_UP | 149 | 36 | 17377 | 2626 |
PLXNC1,MRI1,HEXB,SIKE1,NCKAP1,B4GALT4,TTF1,FAM8A1,CFLAR,NUDT19,C12orf10,CCNA2,GATC,MRPL40,ARID4A,S100A6,SNX25,ARHGAP17,CYFIP1,GTPBP4,CYP20A1,RABIF,ATP6V0A1,PLEKHM3,SERP1,FNTA,DHX16,TMED10,NFIL3,APPL2,CEBPG,QRSL1,CTSA,NCOA1,TRIM32,SMAD4 |
| 2.417e-03 | -6.03 | leukocyte mediated immunity | biological process | GO:0002443 | 625 | 121 | 17256 | 2622 |
RHOG,ADA2,RAB14,KMT2E,ADAM10,DYNLL1,RAC1,HEXB,NIT2,NHLRC3,GYG1,MAPK14,LYN,KCMF1,CMTM6,CPNE3,PA2G4,RAP1A,PSMD1,AP1M1,BRI3,CORO1A,TMBIM1,GM2A,KCNAB2,ENPP4,CPNE1,ERCC1,CCT2,TIMP2,EXOSC6,NRAS,RAB7A,ARHGAP45,PPIE,CYSTM1,PSMB7,ATP6V0A1,CADM1,RAB5B,TOLLIP,ALDH3B1,DSN1,AGPAT2,DDOST,SURF4,RAB24,PSMD3,CAB39,CANT1,ATP6V0C,ROCK1,CLU,PDXK,LTA4H,MAPK1,CAPN1,TUBB,SVIP,MIF,DNAJC5,GMFG,MANBA,PDAP1,LAMTOR3,B4GALT1,ASAH1,CDK13,MAN2B1,RAB6A,PSEN1,TMEM179B,GNS,CD59,PSMD2,CTSS,ARPC5,HUWE1,MSH2,OSTF1,CNN2,MVP,LPCAT1,MSH6,KDELR1,SPTAN1,CYFIP1,FTL,MLEC,RHOA,ADAM17,CREG1,DENND1B,WDR1,HEBP2,C1orf35,ZP3,PKM,ARMC8,CCT8,PRDX1,NEU1,HSPA1B,PI4K2A,CAND1,XRCC5,CAT,RAB18,ATP6V1D,MAGT1,GOLGA7,SNAP29,SNAP23,ACLY,PGRMC1,CEBPG,IMPDH1,CTSA,PSAP,GPI,PGAM1 |
| 2.417e-03 | -6.03 | GSE5542_UNTREATED_VS_IFNA_TREATED_EPITHELIAL_CELLS_24H_DN | MSigDB lists | GSE5542_UNTREATED_VS_IFNA_TREATED_EPITHELIAL_CELLS_24H_DN | 170 | 40 | 17377 | 2626 |
LYRM4,MAX,MPHOSPH8,MEF2A,GLUD1,COX4I1,HMGN3,EPHX2,BZW2,SLC25A37,KIAA1147,PCYOX1L,RPL23A,EEF2K,GTPBP3,NOL11,AP1M1,TPST1,MRPS27,FNIP2,TOP1MT,SEH1L,MRPL32,PTPRK,ZNF84,ZNF780B,PRKAR1B,TBRG4,KIAA1586,KCNQ1,SPPL2B,SMAP2,UBTF,ANKZF1,DCK,CDCA7L,ACBD4,BTF3,CHMP7,USP53 |
| 2.424e-03 | -6.02 | Androgen receptor signaling pathway | WikiPathways | WP138 | 90 | 25 | 5312 | 837 |
NCOR2,RHOA,KAT7,RAC1,BRCA1,UBE2I,PARK7,PRDX1,RHOB,RB1,MDM2,CDC42,PTEN,PIK3R2,PIAS2,ROCK1,NCOA1,ZMIZ1,CREB1,STAT3,SMARCE1,RNF14,SMAD4,NCOA2,CARM1 |
| 2.430e-03 | -6.02 | regulation of DNA-dependent DNA replication | biological process | GO:0090329 | 46 | 15 | 17256 | 2622 |
SMC3,RFC3,CHTF18,CDT1,WDR18,TIMELESS,CHEK2,BLM,ZNF830,RFC2,CDK2,TERF1,TERF2,WRNIP1,STOML2 |
| 2.430e-03 | -6.02 | RNA secondary structure unwinding | biological process | GO:0010501 | 46 | 15 | 17256 | 2622 |
DDX28,DDX56,DDX47,DDX24,EIF4A3,AGO2,DHX9,DDX20,DDX5,DDX31,DDX39A,DDX52,DDX42,DDX23,DDX17 |
| 2.434e-03 | -6.02 | Brain-Derived Neurotrophic Factor (BDNF) signaling pathway | WikiPathways | WP2380 | 144 | 36 | 5312 | 837 |
RHOG,TSC2,RAF1,RPS6KA1,RAC1,PRKAA1,VAV2,CSNK2A1,MEF2A,MAPK14,FOXO3,CDK5,RAP1A,EIF2S2,CDC42,SHC1,DPYSL2,PIK3R2,PTPN11,YBX1,CREB1,STAT3,CFL1,PDPK1,CYFIP1,ADAM17,NCK1,ELK1,MAP2K2,MAPK3,PPP2CA,PTPRF,NSF,STAT1,MAPK1,HRAS |
| 2.439e-03 | -6.02 | GSE15330_WT_VS_IKAROS_KO_LYMPHOID_MULTIPOTENT_PROGENITOR_UP | MSigDB lists | GSE15330_WT_VS_IKAROS_KO_LYMPHOID_MULTIPOTENT_PROGENITOR_UP | 186 | 43 | 17377 | 2626 |
USP7,DNAJC5,RAB11B,HABP4,CUTA,AP3M2,CHIC2,PCSK7,MYO9B,CSNK1A1,ETS1,REEP5,FOXO3,CMTM6,CCDC28A,PIP5K1C,FBRS,CDKN2C,SLC44A1,BCL2,UPF2,CLTB,S100A6,RYBP,VOPP1,RB1CC1,SLBP,SOX4,EDEM2,ECH1,SMAP2,NECAP2,CAT,SAFB,ACOX1,MAP4,FAM3C,OAZ2,LY75,HMGB2,YY1,LONP2,RNF114 |
| 2.439e-03 | -6.02 | GSE10273_HIGH_IL7_VS_HIGH_IL7_AND_IRF4_IN_IRF4_8_NULL_PRE_BCELL_DN | MSigDB lists | GSE10273_HIGH_IL7_VS_HIGH_IL7_AND_IRF4_IN_IRF4_8_NULL_PRE_BCELL_DN | 186 | 43 | 17377 | 2626 |
GALK1,CHERP,TCF3,RMI2,CTCF,SMARCA4,HAUS4,KIF2C,SNN,PPP1R16B,NCAPG,MYEF2,FBXO5,CDKN2C,NRF1,INTS1,PHKG2,TACC3,CARM1,SLC25A1,CSNK1G2,TDP1,PSRC1,TNFAIP3,ASPM,ZNF512,ABCF2,EZR,NUSAP1,TOMM40,KIF11,RHOT2,HSPA1B,XRCC5,RAB24,GPS2,TWSG1,ARNTL,NRM,FAU,UBE2C,AP2S1,FAM72A |
| 2.439e-03 | -6.02 | GSE24972_MARGINAL_ZONE_BCELL_VS_FOLLICULAR_BCELL_IRF8_KO_UP | MSigDB lists | GSE24972_MARGINAL_ZONE_BCELL_VS_FOLLICULAR_BCELL_IRF8_KO_UP | 186 | 43 | 17377 | 2626 |
MIF,EXOC3,C9orf78,SCAMP3,GMFG,LUZP1,TSC2,TRIP10,PRKCSH,ADCK5,APP,PDXDC1,MXD1,HLA-A,UBLCP1,UBXN2A,PDXP,MDM2,BUD31,PRC1,KNTC1,LDLRAD3,F2R,GTF2H2,PTPRK,GINS1,PLK3,DDX24,ANKRD37,PBXIP1,JTB,EZR,UBE2V1,SUMF2,ANLN,SERF2,RAB24,CSK,CLK3,NFIL3,FAM83D,RUVBL2,UBE2C |
| 2.439e-03 | -6.02 | GSE37301_GRANULOCYTE_MONOCYTE_PROGENITOR_VS_RAG2_KO_NK_CELL_DN | MSigDB lists | GSE37301_GRANULOCYTE_MONOCYTE_PROGENITOR_VS_RAG2_KO_NK_CELL_DN | 186 | 43 | 17377 | 2626 |
PTTG1,MRPS26,MYH9,RGS2,APP,CPNE3,RPL23A,WWP2,MLX,SMC3,EIF4A3,TBC1D14,RRBP1,KIF22,MVP,TIPARP,MTPN,PPA1,S100A6,CGGBP1,TMX1,RPAP3,SRSF11,PLK1,IFRD1,MAP4K4,GBA,EZR,WIPF1,MAP7D1,AZI2,TOMM40,LSG1,KIF2A,CDC16,GALNT2,CCDC86,TAB2,PPM1G,ITGB1,SNX14,ABCA1,IPO4 |
| 2.439e-03 | -6.02 | GSE22025_PROGESTERONE_VS_TGFB1_AND_PROGESTERONE_TREATED_CD4_TCELL_UP | MSigDB lists | GSE22025_PROGESTERONE_VS_TGFB1_AND_PROGESTERONE_TREATED_CD4_TCELL_UP | 186 | 43 | 17377 | 2626 |
IER2,GLT8D1,NDUFB6,ADO,MED13L,SLC35B1,IFT27,GGPS1,CPNE3,NDUFS4,SLC31A1,CEP104,ZNF473,EIF2S2,RPL17,PPIL2,AFF1,RP2,GEMIN4,MINPP1,PRPF19,USP34,KLF10,ZNF84,PGGT1B,PPT1,CPOX,SUGP2,WDHD1,MACF1,H2AFV,AKAP1,DDX17,MFN2,RBM25,RPS27A,GOLGA8A,PKD2,RBPJ,YY1,MYL12B,CSNK1D,DDX52 |
| 2.439e-03 | -6.02 | GSE16697_CD4_TCELL_VS_TFH_CD4_TCELL_DN | MSigDB lists | GSE16697_CD4_TCELL_VS_TFH_CD4_TCELL_DN | 186 | 43 | 17377 | 2626 |
CMAS,LIME1,CAST,DAP,RAB23,SLC20A1,RCOR3,APP,GOLM1,ZBTB45,RINL,DPYSL2,IL6ST,SSBP3,BDH1,RAB4A,HADHB,NUP153,RNF19A,METTL9,FRMD8,SMC4,SEPT9,EMB,OXR1,ITM2A,GALNT7,NDRG3,PDE3B,CYB5A,FAS,MTHFD2,GALNT2,CERS6,VPS26B,IMPDH1,LY75,FKBP5,RNASEL,RBPJ,CLN3,ARRB2,DEF6 |
| 2.439e-03 | -6.02 | GSE13493_DP_VS_CD8POS_THYMOCYTE_DN | MSigDB lists | GSE13493_DP_VS_CD8POS_THYMOCYTE_DN | 186 | 43 | 17377 | 2626 |
PPIB,ZNF786,NQO1,KLHL18,VPS25,HDDC2,NOL11,YBX1,AQR,POLR1B,ERI3,SLC12A2,ACSL5,POU2AF1,ELOVL5,GUK1,TCTEX1D2,KAT2A,DPM1,IDH3A,NSDHL,PRKDC,NSUN2,CYP20A1,RPL38,SCFD2,ADSL,EMP3,NFATC2,NUP155,TOMM40,MAP3K4,SGSH,POLE,UAP1,PRDX3,TONSL,PML,MBOAT1,BTF3,CLN3,PFKP,TMEM33 |
| 2.439e-03 | -6.02 | GSE21546_ELK1_KO_VS_SAP1A_KO_AND_ELK1_KO_ANTI_CD3_STIM_DP_THYMOCYTES_UP | MSigDB lists | GSE21546_ELK1_KO_VS_SAP1A_KO_AND_ELK1_KO_ANTI_CD3_STIM_DP_THYMOCYTES_UP | 186 | 43 | 17377 | 2626 |
GORASP1,SHPRH,POC1A,SRSF6,MUM1,ASXL2,TMEM165,METTL3,CNOT3,CRKL,SAP130,MRPL50,FARSA,NRF1,ZNF449,EIF4A3,TTC9C,SLC12A2,STAT3,SCYL3,MLST8,VPS13B,NOL12,ENPP4,SLC39A9,B3GALT6,FAM49B,PBXIP1,FAM118B,RBX1,AACS,HSDL1,CDCA2,TAZ,EVC2,MTMR3,TFDP1,H2AFX,USP32,ZSWIM3,POT1,ANAPC4,ALS2 |
| 2.439e-03 | -6.02 | GSE27786_LIN_NEG_VS_MONO_MAC_DN | MSigDB lists | GSE27786_LIN_NEG_VS_MONO_MAC_DN | 186 | 43 | 17377 | 2626 |
DDX58,CORO7,GGNBP2,GNPDA1,PPP1R15B,BABAM1,RAC1,ACAP1,DAZAP2,C2orf68,KIF5B,MDM2,CTSS,ATG3,SRI,TTC17,CITED2,ATP6V0D1,DCTN1,VPS13B,ELOVL5,CYFIP1,FOXK1,KLF10,NCK1,PPP1R21,EZR,RIT1,SEPT7,HERPUD2,RAB1A,MARK2,MFAP1,STK38,COX8A,YWHAZ,NDUFS5,TMEM159,USF2,PDLIM5,NRBP1,ZC3HAV1,HIGD2A |
| 2.439e-03 | -6.02 | GSE29618_BCELL_VS_PDC_DAY7_FLU_VACCINE_DN | MSigDB lists | GSE29618_BCELL_VS_PDC_DAY7_FLU_VACCINE_DN | 186 | 43 | 17377 | 2626 |
PTMS,TXN,CDK2AP2,HEXB,TMEM109,MAN2B1,TMED3,FKBP2,STMN1,SLC20A1,APP,PARK7,BCAP31,MAN1A1,DST,EIF4A3,DAD1,SIVA1,GRSF1,RRBP1,DAPK1,H2AFY,AHCY,MDFIC,MARCH2,IMPA2,RNF5,SEC61B,MAPKAPK3,IDH3A,MEF2D,SOX4,PON2,SCARB2,SERTAD2,STT3A,TMED10,DUSP3,CERS6,DCK,CORO1C,ST3GAL2,PSAP |
| 2.439e-03 | -6.02 | GSE36826_NORMAL_VS_STAPH_AUREUS_INF_SKIN_UP | MSigDB lists | GSE36826_NORMAL_VS_STAPH_AUREUS_INF_SKIN_UP | 186 | 43 | 17377 | 2626 |
ZNF207,RHOG,CYTIP,CDK2AP2,CHCHD2,TBC1D13,SLC35B1,PARK7,SLC25A37,HNRNPA2B1,RPA2,PSMD1,SHC1,IMPAD1,ANXA5,CLDND1,CORO1A,MOB1A,CHTOP,HNRNPM,ABHD2,BIRC3,HMGN4,SNRPB,MAP4K4,RNPS1,RPL8,PSMA1,DDX39A,DDX17,YIF1A,ADSS,DERL1,HGS,ATP1A1,ORMDL2,TTLL4,HNRNPR,TFE3,PITPNA,LTA4H,LRP8,FUBP1 |
| 2.439e-03 | -6.02 | GSE17721_PAM3CSK4_VS_GADIQUIMOD_12H_BMDC_UP | MSigDB lists | GSE17721_PAM3CSK4_VS_GADIQUIMOD_12H_BMDC_UP | 186 | 43 | 17377 | 2626 |
NDUFV2,H2AFZ,C19orf53,HEXB,TMEM97,NDUFA4,ABCB10,GTF3A,SLC35B1,GLRX3,STMN1,MAPK14,MFSD10,LMNA,RPL23A,CRAT,BDH1,MECR,HADHB,TTC3,RNF26,S100A6,KCNAB2,PREB,RNASEH2C,RPS10,ARHGDIB,WBP1,ARPC1A,CCT8,FKBP3,PSMB3,EPB41,UTP20,DUSP3,PRDX3,DBI,H2AFX,PRMT7,ACADM,CHEK2,UBE2C,SSSCA1 |
| 2.439e-03 | -6.02 | GSE37416_0H_VS_12H_F_TULARENSIS_LVS_NEUTROPHIL_UP | MSigDB lists | GSE37416_0H_VS_12H_F_TULARENSIS_LVS_NEUTROPHIL_UP | 186 | 43 | 17377 | 2626 |
CDS2,ADD1,PPP1R12A,GLUD1,HAUS4,NOTCH2,SLC25A44,IKBIP,SLC12A9,REEP5,RMI1,ADD3,TBC1D14,RNF135,MVP,TTLL12,GTF2H2,S100A6,MYO5A,PTPN18,FAM172A,PBXIP1,SELPLG,TOPORS,BICD2,STK17B,SMAP2,EPB41,RAB18,NUCB1,HHEX,PRDX3,ACOX1,USP32,LY75,TMEM219,CAB39,ATF6,YWHAH,MAPK1,TOB1,CAPN1,GEMIN7 |
| 2.439e-03 | -6.02 | GSE27786_LSK_VS_LIN_NEG_CELL_DN | MSigDB lists | GSE27786_LSK_VS_LIN_NEG_CELL_DN | 186 | 43 | 17377 | 2626 |
BCCIP,MRPL42,PDAP1,UROD,TRMT6,CDCA3,TMEM97,C5orf30,ADPGK,SLC20A1,NDUFS7,PNO1,LMNA,RAD23A,GOLM1,MRPL50,LYAR,CCNA2,IL6ST,MBD2,BDH1,LMAN1,MRPL11,TTLL12,SAP30,DDX28,GUK1,ASPM,IDH3A,MTA2,MRS2,NARF,SLC25A22,BRCA1,EIF3A,NECAP2,SDHB,PON2,MID1IP1,SPATA2,PPM1G,GEN1,NIPA1 |
| 2.439e-03 | -6.02 | GSE11924_TFH_VS_TH17_CD4_TCELL_DN | MSigDB lists | GSE11924_TFH_VS_TH17_CD4_TCELL_DN | 186 | 43 | 17377 | 2626 |
BCCIP,DNAJC2,NDUFA5,CLSPN,NOP2,SEC61G,RAE1,CUL1,NIT2,HAUS2,FBXO5,RTKN,SLC31A1,CTNNBL1,NDUFA2,PIN1,EXOSC1,CS,TAGLN2,AQR,METTL9,SEH1L,PPAN,RPL35,NASP,RAD51AP1,SMU1,RABIF,EXOSC9,RIT1,RPL27A,AKAP1,YIF1A,EIF3K,DGCR8,ACAT1,ANP32E,SRSF3,NDE1,ZNF830,ABCA1,VPS29,ZNF511 |
| 2.442e-03 | -6.01 | importin-alpha family protein binding | molecular function | GO:0061676 | 5 | 4 | 17224 | 2647 |
RB1,GOLGA2,DHX9,TPX2 |
| 2.450e-03 | -6.01 | ANXA2 (annexin A2) | protein interactions | 302 | 125 | 33 | 17029 | 2761 |
RAB14,CYLD,EWSR1,MYH9,APP,CDC73,RPL11,RPA2,PCNA,DNAJC8,CDC42,SHC1,PTEN,MCM5,STAT3,S100A6,PCBP2,RAB7A,MCM2,ISG15,RPA1,MAP3K4,PDCD6,STAT6,MYO18A,H2AFX,KLHL42,CDK2,ARRB2,TERF1,POT1,ANXA11,FUBP1 |
| 2.456e-03 | -6.01 | V-type ATPase, eukaryotes | KEGG pathways | hsa_M00160 | 24 | 10 | 7161 | 1149 |
ATP6V0B,ATP6V1D,ATP6V0A2,ATP6V0A1,ATP6V0C,ATP6V1C1,ATP6V1B2,ATP6V0E1,ATP6V0D1,ATP6V1G1 |
| 2.456e-03 | -6.01 | V-type ATPase, eukaryotes | KEGG pathways | M00160 | 24 | 10 | 7161 | 1149 |
ATP6V0B,ATP6V1D,ATP6V0A2,ATP6V0A1,ATP6V0C,ATP6V1C1,ATP6V1B2,ATP6V0E1,ATP6V0D1,ATP6V1G1 |
| 2.461e-03 | -6.01 | NR4A1 (nuclear receptor subfamily 4 group A member 1) | protein interactions | 3164 | 106 | 29 | 17029 | 2761 |
POLA2,NCOR2,VHL,MTA2,RPS6KA1,CHD1L,CUTA,ATXN1,GLUD1,ANKIB1,TRIM28,GLOD4,HNRNPA2B1,VASP,CHD3,RBL1,SOCS4,PML,AXIN2,YWHAZ,BCL2,CHEK2,NCOA1,MAPK1,STAT3,SMARCE1,NCOA2,FAF1,RLIM |
| 2.465e-03 | -6.01 | RACGAP1 (Rac GTPase activating protein 1) | protein interactions | 29127 | 92 | 26 | 17029 | 2761 |
PKP4,NRAS,BAZ2A,AKT2,CUL1,KIF23,RACGAP1,AURKB,CAPZA2,WDR5,MPG,SHCBP1,ERC1,MAP3K4,VAV1,PSMD1,SYNCRIP,STX18,TANK,PRC1,C2CD5,MICAL3,IFI16,SMNDC1,CSTF1,CDC5L |
| 2.469e-03 | -6.00 | IL-3 Signaling Pathway | WikiPathways | WP286 | 49 | 16 | 5312 | 837 |
TGFB1,CRKL,VAV1,JAK1,SHC1,RAF1,PIK3R2,PTPN11,BCL2,BCL2L1,STAT3,MAPK1,PRKACA,LYN,HRAS,MAPK3 |
| 2.478e-03 | -6.00 | translation initiation factor activity | molecular function | GO:0003743 | 50 | 16 | 17224 | 2647 |
EIF3L,DHX29,EIF3D,AGO2,EIF2A,EIF1B,EIF4G2,EIF4H,EIF3G,EIF3A,EIF3H,MCTS1,EIF3K,EIF2S2,EIF2D,EIF5 |
| 2.491e-03 | -5.99 | TOOKER_GEMCITABINE_RESISTANCE_UP | MSigDB lists | TOOKER_GEMCITABINE_RESISTANCE_UP | 74 | 21 | 17377 | 2626 |
ACSL5,AATF,KIAA0100,SNRPB,CPOX,RRM1,CIRBP,ARFIP2,RPL15,TMED3,ODC1,ABHD14A,ISG15,XRCC5,PFDN5,PON2,HSPA4,COX8A,NAP1L4,CD81,PTDSS1 |
| 2.499e-03 | -5.99 | central_nervous_system-brain-glioma-oligoastrocytoma | COSMIC cancer mutations | central_nervous_system-brain-glioma-oligoastrocytoma | 47 | 15 | 17385 | 2587 |
CDKN2C,PPP2CA,RB1,ATXN3,PTEN,RB1CC1,CIC,MEMO1,CS,MCCC1,TIA1,NUP153,CDKN2A,FUBP1,USP34 |
| 2.503e-03 | -5.99 | DNA-directed RNA polymerase II, core complex | cellular component | GO:0005665 | 18 | 8 | 18223 | 2701 |
POLR2I,POLR2J,POLR2G,POLR2L,POLR2K,ZNF768,POLR2D,POLR2A |
| 2.503e-03 | -5.99 | microtubule plus-end | cellular component | GO:0035371 | 18 | 8 | 18223 | 2701 |
DST,KIF2C,MAPRE2,MAPRE1,KIF18B,MYO5A,SPAG5,DCTN1 |
| 2.506e-03 | -5.99 | Autodegradation of Cdh1 by Cdh1:APC/C | REACTOME pathways | R-HSA-174084 | 64 | 20 | 10287 | 1696 |
PSMB7,PSMA1,ANAPC2,CDC23,PSMD9,PSMB9,PSMB3,PSMC4,PSMD2,PSMA6,CDC16,PSMD1,CDC27,RPS27A,PSMD3,PSMD8,ANAPC7,UBE2C,PSMC1,ANAPC4 |
| 2.509e-03 | -5.99 | Pre-NOTCH Expression and Processing | REACTOME pathways | R-HSA-1912422 | 47 | 16 | 10287 | 1696 |
KAT2A,AGO2,E2F3,MFNG,B4GALT1,RAB6A,NOTCH2,POFUT1,ATP2A2,TFDP1,SEL1L,E2F1,RBPJ,MAML1,TFDP2,TMED2 |
| 2.526e-03 | -5.98 | PUIFFE_INVASION_INHIBITED_BY_ASCITES_DN | MSigDB lists | PUIFFE_INVASION_INHIBITED_BY_ASCITES_DN | 139 | 34 | 17377 | 2626 |
SEPHS2,THOC1,IVNS1ABP,WDR13,LAMTOR3,DNAJC24,PRPF18,NDUFV1,PDCD10,NOL11,TNFAIP8,RABGAP1L,RBM34,ZNHIT6,ZNF226,PCYT2,TP53BP2,MOSPD1,RYBP,PTPRK,MOB4,ELOVL5,AMD1,ZBED5,MTMR6,CHMP2B,SOX4,KLF6,SH3GLB1,PLEKHF2,BTBD1,ZNF330,RGL1,POT1 |
| 2.526e-03 | -5.98 | GSE2405_S_AUREUS_VS_UNTREATED_NEUTROPHIL_UP | MSigDB lists | GSE2405_S_AUREUS_VS_UNTREATED_NEUTROPHIL_UP | 181 | 42 | 17377 | 2626 |
EXOC3,ZCCHC9,AGPAT3,AKT1S1,SLC35B2,BRIX1,MRPL19,HAUS2,IRF4,ERH,FBXL6,NOL11,AHSA1,NOC2L,ARHGEF2,C8orf59,GTF2H2,MED22,SRPK2,TTPAL,TDP1,AATF,KIAA0040,SIGMAR1,NET1,OXR1,PPIE,NOL8,NDUFA7,COMMD4,MBD3,GIGYF1,FAS,PRDX3,TWSG1,CHCHD1,NDUFA11,GALNT10,RUVBL2,PDCD11,HIGD2A,ESYT2 |
| 2.526e-03 | -5.98 | GSE11961_MEMORY_BCELL_DAY7_VS_GERMINAL_CENTER_BCELL_DAY40_DN | MSigDB lists | GSE11961_MEMORY_BCELL_DAY7_VS_GERMINAL_CENTER_BCELL_DAY40_DN | 181 | 42 | 17377 | 2626 |
RECQL,ADD1,MANBA,DAP,TRMT6,CBLL1,ZFYVE21,ARGLU1,TBC1D13,CDIPT,MAP1LC3B,ZADH2,ANKRD23,CAPN2,NFATC3,FUT8,RAB4A,TAF5L,CITED2,FRMD8,ALDH9A1,POU2AF1,ORAI2,PPP3CA,AACS,ZMYND11,NUDT4,TEX10,CIRBP,PLEKHM3,CBFA2T2,CAT,SGSH,PPP2R5A,WDR11,MFAP1,DCK,RBMX,APPL2,SH3GLB2,MEGF9,ZMIZ1 |
| 2.526e-03 | -5.98 | GSE4142_GC_BCELL_VS_MEMORY_BCELL_DN | MSigDB lists | GSE4142_GC_BCELL_VS_MEMORY_BCELL_DN | 181 | 42 | 17377 | 2626 |
SLC41A1,FAM53C,TRAK1,MYNN,NUF2,RCOR3,MIS12,TMEM179B,OIP5,ASAP2,TNFAIP8,LRRC8D,BDH1,ZFYVE27,APOOL,FBXL19,SMARCE1,HNRNPM,B3GALT6,PHF20L1,NCK1,MRS2,CIRBP,AURKB,PPFIA3,GINS4,AMZ2,TMEM127,PFDN5,ATAD2,TMED10,BIRC5,CSNK1G1,OAZ2,COX8A,USP20,ACBD4,CLN3,CD81,C11orf1,TSPAN5,HIPK3 |
| 2.526e-03 | -5.98 | GSE7568_CTRL_VS_24H_TGFB_TREATED_MACROPHAGES_WITH_IL4_AND_DEXAMETHASONE_UP | MSigDB lists | GSE7568_CTRL_VS_24H_TGFB_TREATED_MACROPHAGES_WITH_IL4_AND_DEXAMETHASONE_UP | 181 | 42 | 17377 | 2626 |
HECA,MAGEH1,STARD7,RAB23,GLUD1,ARGLU1,EIF1B,FOXO3,BIRC2,FZD6,TMCC3,WRNIP1,CCNK,ADCY9,MECR,PARL,PDCD2,UPF2,ZNF770,RNF169,RYBP,ACP2,HEMK1,ANKRD37,ZNF512,SLC26A6,MFNG,LRP5,ADRB2,IL12RB1,PNPLA8,TAZ,RHOB,ARHGAP15,KIF2A,DNAJC10,WNT5B,DDX5,BEND6,ZNF146,HDAC2,RNF114 |
| 2.526e-03 | -5.98 | GSE22527_ANTI_CD3_INVIVO_VS_UNTREATED_MOUSE_TREG_UP | MSigDB lists | GSE22527_ANTI_CD3_INVIVO_VS_UNTREATED_MOUSE_TREG_UP | 181 | 42 | 17377 | 2626 |
MUT,ACTR3,GADD45G,MYH9,KLC1,PTP4A3,CDK13,RGS1,LMNA,CREM,MOAP1,CD59,CAPN2,MEX3C,SP100,SAR1A,IL6ST,DCP1A,CNN2,ECD,TFG,RBM15,USP34,PPIF,PLK3,CLCN3,RHOBTB3,TMEM39A,AMD1,PFKFB3,DNAJA1,ADRB2,SRSF5,SCARB2,HGS,FBXO28,HIPK2,AEN,PPP1R11,PITPNA,CHPF2,MAPK1 |
| 2.526e-03 | -5.98 | GSE23925_LIGHT_ZONE_VS_NAIVE_BCELL_DN | MSigDB lists | GSE23925_LIGHT_ZONE_VS_NAIVE_BCELL_DN | 181 | 42 | 17377 | 2626 |
COMMD10,COX15,FAM208B,MZT1,PPCS,KDM4A,CIB1,TIA1,LANCL1,ZADH2,PITHD1,MRPL19,FAM192A,PSMA6,MBD2,SLC35B4,UPF2,PIK3IP1,TTLL12,ATF2,TIPARP,FGFR1OP2,MED22,CSTF1,DDX28,HEMK1,SNX2,BTG2,VHL,WDR82,TAZ,GUF1,ANKRD46,IWS1,ADSS,CDC27,PDRG1,MFAP1,LUC7L3,DCAF11,SLC16A1,GCSH |
| 2.527e-03 | -5.98 | GO_PROTEIN_LOCALIZATION_TO_VACUOLE | MSigDB lists | GO_PROTEIN_LOCALIZATION_TO_VACUOLE | 42 | 14 | 17377 | 2626 |
NAGPA,SCARB2,GCC2,HGS,TNFAIP3,RAB35,RAB7A,VTI1A,TOLLIP,BECN1,SMURF1,CD81,VPS25,SH3GLB1 |
| 2.527e-03 | -5.98 | REACTOME_DEADENYLATION_DEPENDENT_MRNA_DECAY | MSigDB lists | REACTOME_DEADENYLATION_DEPENDENT_MRNA_DECAY | 42 | 14 | 17377 | 2626 |
EXOSC6,EXOSC7,EIF4A3,LSM6,EXOSC1,DCP1A,EXOSC9,CNOT6,PARN,PATL1,PABPC1,PAIP1,CNOT3,EDC3 |
| 2.527e-03 | -5.98 | IKEDA_MIR133_TARGETS_UP | MSigDB lists | IKEDA_MIR133_TARGETS_UP | 42 | 14 | 17377 | 2626 |
PPP2CA,SEC61B,CYLD,PPP1R12A,CDC42,ARPC5,MAFK,RBMX,ACTR3,USP32,MYH9,PITPNB,RBPJ,MAML1 |
| 2.536e-03 | -5.98 | GO_BLASTOCYST_DEVELOPMENT | MSigDB lists | GO_BLASTOCYST_DEVELOPMENT | 60 | 18 | 17377 | 2626 |
GINS1,SP3,NASP,XAB2,CUL3,RTF1,ZP3,GINS4,CNOT3,MFN2,PSMC4,CAPN2,PALB2,DAD1,CTR9,ZNF830,BYSL,PRPF19 |
| 2.536e-03 | -5.98 | GEORGES_CELL_CYCLE_MIR192_TARGETS | MSigDB lists | GEORGES_CELL_CYCLE_MIR192_TARGETS | 60 | 18 | 17377 | 2626 |
TDP1,MCM10,MKI67,KIF23,CTCF,RACGAP1,BRCA1,MACF1,CDC73,MIS12,DLG5,DTL,RB1,NEK1,SERTAD2,KIF14,BCL2,POLQ |
| 2.536e-03 | -5.98 | REACTOME_SIGNALING_BY_TGF_BETA_RECEPTOR_COMPLEX | MSigDB lists | REACTOME_SIGNALING_BY_TGF_BETA_RECEPTOR_COMPLEX | 60 | 18 | 17377 | 2626 |
FKBP1A,TGFB1,UBE2D3,CCNC,NCOR2,RHOA,SMAD2,MTMR4,RBL1,RPS27A,UCHL5,E2F4,TFDP1,MEN1,SMURF1,STRAP,SMAD4,PARD3 |
| 2.536e-03 | -5.98 | organelle transport along microtubule | biological process | GO:0072384 | 69 | 20 | 17256 | 2622 |
KIF3B,TRAK1,AP3M2,KIF23,BICD2,RAB6A,RAB1A,RHOT1,AP3S1,RHOT2,COPG2,TMEM201,KIF5B,CDC42,AP3S2,LRPPRC,KIFAP3,NDE1,CLN3,SNAPIN |
| 2.536e-03 | -5.98 | negative regulation of response to DNA damage stimulus | biological process | GO:2001021 | 69 | 20 | 17256 | 2622 |
BCL2L12,MIF,PGAP2,ERCC1,TRIP12,THOC1,HELB,BCL2L1,PTTG1IP,CYREN,MDM2,KLHL15,PARPBP,CHEK2,CLU,TRIM32,OGG1,RNF169,TERF2,POLQ |
| 2.538e-03 | -5.98 | central_nervous_system-cerebellum-glioma-astrocytoma_Grade_II | COSMIC cancer mutations | central_nervous_system-cerebellum-glioma-astrocytoma_Grade_II | 11 | 6 | 17385 | 2587 |
KRAS,NRAS,H3F3A,PTEN,HRAS,CDKN2A |
| 2.538e-03 | -5.98 | stomach-carcinoma-tubular_adenocarcinoma | COSMIC cancer mutations | stomach-carcinoma-tubular_adenocarcinoma | 11 | 6 | 17385 | 2587 |
KRAS,STK11,NRAS,SF3B1,HRAS,MSH6 |
| 2.538e-03 | -5.98 | endometrium-carcinoma-mixed_adenosquamous_carcinoma | COSMIC cancer mutations | endometrium-carcinoma-mixed_adenosquamous_carcinoma | 11 | 6 | 17385 | 2587 |
KRAS,NRAS,PTEN,HRAS,SF3B1,CDKN2A |
| 2.538e-03 | -5.98 | skin-scalp-malignant_melanoma-lentigo_maligna | COSMIC cancer mutations | skin-scalp-malignant_melanoma-lentigo_maligna | 11 | 6 | 17385 | 2587 |
KRAS,STK11,NRAS,PTEN,HRAS,CDKN2A |
| 2.538e-03 | -5.98 | tubular_adenocarcinoma | COSMIC cancer mutations | tubular_adenocarcinoma | 11 | 6 | 17385 | 2587 |
KRAS,STK11,NRAS,SF3B1,HRAS,MSH6 |
| 2.542e-03 | -5.97 | LSM4 (LSM4 homolog, U6 small nuclear RNA and mRNA degradation associated) | protein interactions | 25804 | 65 | 20 | 17029 | 2761 |
PPIB,COX5B,ZBTB10,OLA1,RMI2,SMU1,LSM8,PRPF3,MTR,PRPF18,RAD23A,SYNCRIP,RPL32,HUWE1,L3MBTL3,LSM6,WDR44,HNRNPR,LRPPRC,PRPF4 |
| 2.542e-03 | -5.97 | KIF1BP (KIF1 binding protein) | protein interactions | 26128 | 65 | 20 | 17029 | 2761 |
METTL1,KIF3B,TP53RK,ACTR3,NSUN2,KIF15,PTP4A3,RANGAP1,GORASP2,EFL1,SH3GLB1,GSTK1,STARD9,KIF18A,KIF18B,KIF13B,KIF14,WDR4,FKBP5,TERF1 |
| 2.542e-03 | -5.97 | BIRC5 (baculoviral IAP repeat containing 5) | protein interactions | 332 | 65 | 20 | 17029 | 2761 |
BIRC3,PRKDC,CDCA8,E2F3,XIAP,AURKB,BECN1,BIRC2,RB1,MED10,MED8,BIRC5,E2F4,LAMTOR4,E2F1,H2AFX,FBXL7,USF2,CDK2,MED22 |
| 2.542e-03 | -5.97 | CYFIP1 (cytoplasmic FMR1 interacting protein 1) | protein interactions | 23191 | 65 | 20 | 17029 | 2761 |
WASF2,CYFIP1,TRIP10,RAC1,NCKAP1,IKBIP,FXR1,BZW2,PCNA,EFTUD2,ARHGEF1,ZNF746,YWHAZ,YWHAH,ABI1,TERF1,TIMM50,TERF2,ZNF511,DCTN1 |
| 2.542e-03 | -5.97 | SPACA1 (sperm acrosome associated 1) | protein interactions | 81833 | 65 | 20 | 17029 | 2761 |
GOLIM4,TMEM126B,KIAA1586,COMMD4,MAD2L2,FASTKD3,DTWD1,RAD51C,INTS7,TATDN2,BDH1,STAT1,AP1M1,UPK3BL1,LTN1,MICU2,ECPAS,IMPA2,TYW1B,VPS13B |
| 2.542e-03 | -5.97 | UXT (ubiquitously expressed prefoldin like chaperone) | protein interactions | 8409 | 65 | 20 | 17029 | 2761 |
RPAP3,POLR2I,NCK1,VHL,E2F3,APP,POLR2A,CEP104,PFDN4,PDRG1,RBL1,SIAH1,E2F4,LIMK1,LRPPRC,E2F1,RUVBL2,GLE1,E2F2,MCPH1 |
| 2.542e-03 | -5.97 | CLTA (clathrin light chain A) | protein interactions | 1211 | 65 | 20 | 17029 | 2761 |
MAPRE1,TWNK,RBM8A,CUL3,MYBL2,MYH9,CAPZA2,RGS2,ANLN,SEC16A,MAP1LC3B,PICALM,APPL1,MAD2L2,MYO18A,GTSE1,CLTB,TFG,CDK2,ARRB2 |
| 2.557e-03 | -5.97 | snRNA metabolic process | biological process | GO:0016073 | 98 | 26 | 17256 | 2622 |
INTS2,POLR2I,EXOSC6,RPRD1A,POLR2G,POLR2L,POLR2K,ELL2,INTS13,POLR2D,EXOSC9,SNAPC4,SRRT,POLR2A,GTF2F1,CCNK,EXOSC7,POLR2J,INTS7,INTS1,NABP2,NABP1,INTS12,ICE2,TAF6,RPRD1B |
| 2.560e-03 | -5.97 | MYO1B (myosin IB) | protein interactions | 4430 | 52 | 17 | 17029 | 2761 |
CYLD,TCF3,MYH9,CUL1,CSNK2A1,CAPZA2,ANLN,STYXL1,RPA1,RPA2,PTEN,MYO18A,ZNF746,BCL7C,DAPK1,ECPAS,CDK2 |
| 2.560e-03 | -5.97 | Snw1 (SNW domain containing 1) | protein interactions | 66354 | 52 | 17 | 17029 | 2761 |
SNRNP200,CDC40,XAB2,PPIE,CRNKL1,DHX8,SNRPD3,TMEM165,DHX15,HOMER1,GOLGA4,KLF16,EFTUD2,AQR,KCNAB2,CDC5L,PRPF19 |
| 2.560e-03 | -5.97 | MRPS15 (mitochondrial ribosomal protein S15) | protein interactions | 64960 | 52 | 17 | 17029 | 2761 |
MRPS2,NOA1,PRKAR1B,MRPS26,CUL3,MRPS10,ORC1,MRPS14,CDC73,CAND1,DAP3,STRBP,COQ4,GRSF1,MRPS27,DUSP11,TRMT10B |
| 2.560e-03 | -5.97 | AQR (aquarius intron-binding spliceosomal factor) | protein interactions | 9716 | 52 | 17 | 17029 | 2761 |
XAB2,SUZ12,PPIE,CRNKL1,DHX8,BLM,RBM4,SF3A2,EIF4A3,PPP4R1,YJU2,PQBP1,ISY1-RAB43,SNRPG,ZNF830,NKAPD1,PRPF19 |
| 2.560e-03 | -5.97 | PQBP1 (polyglutamine binding protein 1) | protein interactions | 10084 | 52 | 17 | 17029 | 2761 |
POU3F2,MAPRE1,EWSR1,ATXN1,NDUFA7,PCGF1,TXNL4A,SF3A2,APP,POLR2A,SUGP1,RAB8A,GOLGA2,RRBP1,RBMS1,AQR,CLTB |
| 2.560e-03 | -5.97 | PPP4R2 (protein phosphatase 4 regulatory subunit 2) | protein interactions | 151987 | 52 | 17 | 17029 | 2761 |
AMPD2,TRAPPC13,NPHP4,CUTA,PSMA1,USP10,DDX20,FAM133B,DNAJA1,MCM2,CLNS1A,VASP,CCDC6,PPME1,TRA2B,GEMIN4,IGBP1 |
| 2.564e-03 | -5.97 | human chr19p13.13 | chromosome location | human chr19p13.13 | 40 | 11 | 26185 | 2809 |
FARSA,IER2,C19orf53,DHPS,TRIR,MRI1,TNPO2,ASNA1,MAN2B1,RNASEH2A,RAD23A |
| 2.564e-03 | -5.97 | positive regulation of mitochondrion organization | biological process | GO:0010822 | 118 | 30 | 17256 | 2622 |
UBE2D3,BAK1,PPIF,ATP5IF1,DYNLL1,PRKAA1,GBA,PARK7,APOPT1,SH3GLB1,USP36,OPTN,STOML2,MFN2,MIEF1,MOAP1,HUWE1,FBXO7,TFDP1,E2F1,PPP3R1,BCL2,YWHAZ,ATG13,TP53BP2,TFDP2,SMURF1,YWHAH,HTRA2,CDC37 |
| 2.568e-03 | -5.96 | USP21 (ubiquitin specific peptidase 21) | protein interactions | 27005 | 135 | 35 | 17029 | 2761 |
DDX58,USP7,PPIB,ATXN3,NF1,FAM53C,RBM8A,USP48,RTKN,ANKRD28,ZBTB21,KIF13B,ARHGEF2,JOSD1,CDC25B,LRSAM1,TRIM8,BAZ2A,DENND4C,CUL3,PCGF6,RAB3IP,USP21,MARK2,ISG15,GIGYF1,MAPK3,AFDN,FAM110A,MAP4,USP20,BEND3,PPP6R3,SLF1,ESPL1 |
| 2.570e-03 | -5.96 | GO_REGULATION_OF_CELLULAR_COMPONENT_BIOGENESIS | MSigDB lists | GO_REGULATION_OF_CELLULAR_COMPONENT_BIOGENESIS | 724 | 137 | 17377 | 2626 |
PDCD6IP,AGRN,ADD1,SIRT2,UBQLN2,MIEN1,PPP1R16B,BIRC2,PARK7,EEF2K,RAP1A,CDC42,ATG3,DNM2,FNIP2,MTPN,MLST8,PLK1,ERCC1,SEPT9,NCK1,RBX1,GMFB,EZR,BRCA1,DPYSL3,TBC1D17,WAS,LIMK1,MAP4,ATXN2L,ROCK1,PIEZO1,VPS4A,CLU,PSMC1,SVIP,TBC1D12,MAPRE1,GMFG,HJURP,PHF23,DNAJB2,PRKAA1,KCTD17,DNAJB1,NCKAP1,RGS2,JMY,RB1,VASP,ARPC5,XPA,CAPZA1,PIKFYVE,LRSAM1,CYFIP1,LDB1,PIP4K2C,BCLAF1,CAPZA2,SEPT7,ARPC1A,DAPK3,CAND1,FAS,PSMC4,TSC1,ORMDL2,ODF2,ARAP1,CNOT6,SAMD8,PDLIM5,WASF2,RHOG,CHMP2A,ANKRD27,FEZ2,CYLD,RAF1,ACTR3,CHD1L,RAC1,TBC1D13,TWF2,STMN1,PRKACA,STAM,RRN3,TBC1D22A,RALB,TBC1D14,KIF14,CDKN1B,CORO1A,PSRC1,RAB7A,VDAC2,TUBGCP5,WIPF1,CHMP2B,IDE,CHMP4A,PEX5,CORO1C,CBLN2,CHMP4B,NCLN,MECP2,FLOT1,ARFIP2,ARF1,TUBGCP2,PIP4K2A,RPA2,PTEN,CENPJ,PTPN11,CREB1,CNOT6L,GTF2H2,RNF5,SPTAN1,TGFB1,RHOA,MACF1,SH3GLB1,HSPA1B,RPA1,MTMR3,STX18,PARP10,TERF1,HRAS,DDB1,FAF1 |
| 2.570e-03 | -5.96 | GSE4590_SMALL_VS_VPREB_POS_LARGE_PRE_BCELL_UP | MSigDB lists | GSE4590_SMALL_VS_VPREB_POS_LARGE_PRE_BCELL_UP | 160 | 38 | 17377 | 2626 |
ZBTB10,LUZP1,NF1,SHPRH,CUL1,NIT2,EIF2AK4,GGA2,LCLAT1,CCDC28A,ATP6V0B,CCDC50,ETV6,BRD7,KIFAP3,BCAP29,UBE3C,GTF2H2,SLC12A2,ARID4A,NCOA2,TERF2,ACSL5,MLEC,AATF,POLK,MAP4K4,NOL8,DCTD,TOMM40,ZFR,VEZF1,BRWD1,PDRG1,OGT,CCDC125,PPP5C,BRD9 |
| 2.570e-03 | -5.96 | GSE45365_WT_VS_IFNAR_KO_BCELL_MCMV_INFECTION_DN | MSigDB lists | GSE45365_WT_VS_IFNAR_KO_BCELL_MCMV_INFECTION_DN | 160 | 38 | 17377 | 2626 |
TMEM106C,HIVEP3,LIME1,MCM10,HJURP,C1orf112,PTTG1,CDCA3,NUF2,KIF2C,TCF19,SPAG5,OIP5,RNF121,DAD1,PCYT2,MARCH2,PLK1,SNX25,MKI67,CKAP2L,FAM50B,MCM2,ASF1B,ISG15,INF2,CDCA4,KIF18B,BIRC5,NEIL3,CEP55,CDCA5,FAM83D,CCNB2,ESPL1,USP53,BYSL,POLQ |
| 2.575e-03 | -5.96 | KISc | smart domains | SM00129 | 44 | 14 | 9493 | 1367 |
KIF5B,KIFC1,KIF2A,KIF3B,STARD9,KIF18A,KIF18B,KIF14,KIF13B,KIF15,KIF23,KIF22,KIF2C,KIF11 |
| 2.576e-03 | -5.96 | E2F_TDP | pfam domains | PF02319 | 11 | 6 | 17054 | 2545 |
TFDP2,E2F2,E2F4,TFDP1,E2F1,E2F3 |
| 2.582e-03 | -5.96 | telomere maintenance | biological process | GO:0000723 | 108 | 28 | 17256 | 2622 |
POLA2,ERCC1,TELO2,RFC3,PRIM2,PRKDC,SMC6,DCLRE1C,BLM,RFC2,GAR1,PRIM1,XRCC5,RPA1,TERF2IP,RPA2,RAD51C,PCNA,UPF1,SP100,POLE,NSMCE2,XRCC3,PTGES3,POT1,TERF1,RAD51D,TERF2 |
| 2.583e-03 | -5.96 | ATIC (5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase) | protein interactions | 471 | 74 | 22 | 17029 | 2761 |
TXN,SUMO2,ARMT1,ADSL,GLO1,SPR,SNRPA,ISG15,CLNS1A,MCTS1,CAPN2,GART,JAK1,ATIC,NSFL1C,TARDBP,AHCY,TATDN1,CDK2,HNRNPDL,ASB6,KCNAB2 |
| 2.583e-03 | -5.96 | XPNPEP1 (X-prolyl aminopeptidase 1) | protein interactions | 7511 | 74 | 22 | 17029 | 2761 |
UBE2D3,POLA2,KARS,GNPDA1,EZR,ADSL,NUTF2,API5,PSMD9,H2AFV,C12orf10,NUCB1,PCNA,ATP6V1D,PLAA,UCHL5,RAD23B,WDR4,TARDBP,HEXA,ASB6,NUDT3 |
| 2.584e-03 | -5.96 | Homologous DNA Pairing and Strand Exchange | REACTOME pathways | R-HSA-5693579 | 43 | 15 | 10287 | 1696 |
RPA2,RAD51C,RFC3,PALB2,RAD51AP1,XRCC2,RMI2,TOP3A,XRCC3,BRCA1,BLM,RFC2,RMI1,RAD51D,RPA1 |
| 2.600e-03 | -5.95 | protein-DNA complex assembly | biological process | GO:0065004 | 234 | 52 | 17256 | 2622 |
HJURP,UBN1,SHPRH,CDT1,CENPF,CHD1L,SMARCA4,TAF6L,MIS12,OIP5,RPA2,RRN3,XPA,RAD23B,XRCC2,H2AFY,ANP32A,CENPM,NAP1L4,ORC3,GTF2H2,HP1BP3,NASP,RBX1,TSPYL4,BAZ2A,WDR18,MCM2,ASF1B,CENPU,CHAF1A,RPA1,TAF2,UBTF,RAD51C,NAP1L1,BRD2,RPS27A,H2AFX,ANP32E,XRCC3,HMGB2,CABIN1,CENPT,TAF12,H3F3A,RBBP4,TAF6,NAA60,DDB1,IPO4,RAD51D |
| 2.608e-03 | -5.95 | Resolution of D-Loop Structures | REACTOME pathways | R-HSA-5693537 | 35 | 13 | 10287 | 1696 |
RAD51C,PALB2,RAD51AP1,XRCC2,RMI2,TOP3A,XRCC3,BRCA1,BLM,GEN1,RMI1,SPIDR,RAD51D |
| 2.608e-03 | -5.95 | MODULE_325 | MSigDB lists | MODULE_325 | 51 | 16 | 17377 | 2626 |
POLR2K,TPX2,UBE2Z,EDEM2,CYB5A,RBM38,PRIM1,DECR1,PDK2,GSDMB,RAB24,PFDN4,BDH1,CDCA5,SIAH2,MRPL48 |
| 2.608e-03 | -5.95 | GO_TRNA_AMINOACYLATION | MSigDB lists | GO_TRNA_AMINOACYLATION | 51 | 16 | 17377 | 2626 |
FARSA,KARS,EPRS,LARS,GATC,IARS,HARS,MRPL39,QARS,PPA2,IARS2,QRSL1,POLG2,PPA1,TARS,CARS2 |
| 2.608e-03 | -5.95 | GO_INTRINSIC_APOPTOTIC_SIGNALING_PATHWAY_BY_P53_CLASS_MEDIATOR | MSigDB lists | GO_INTRINSIC_APOPTOTIC_SIGNALING_PATHWAY_BY_P53_CLASS_MEDIATOR | 51 | 16 | 17377 | 2626 |
PGAP2,TMEM109,TOPORS,PDK2,HINT1,HIPK2,MSH2,E2F1,PML,AEN,DDX5,STK11,TP53BP2,E2F2,ZMAT3,IFI16 |
| 2.608e-03 | -5.95 | REACTOME_DESTABILIZATION_OF_MRNA_BY_AUF1_HNRNP_D0 | MSigDB lists | REACTOME_DESTABILIZATION_OF_MRNA_BY_AUF1_HNRNP_D0 | 51 | 16 | 17377 | 2626 |
PSMA8,PSMB7,PSMA1,PSMB9,PSMD9,PSMB3,HSPA1B,PSMC4,PSMD2,PSMA6,PSMD1,RPS27A,PSMD3,PSMD8,PABPC1,PSMC1 |
| 2.608e-03 | -5.95 | GO_AMINO_ACID_ACTIVATION | MSigDB lists | GO_AMINO_ACID_ACTIVATION | 51 | 16 | 17377 | 2626 |
FARSA,KARS,EPRS,LARS,GATC,IARS,HARS,MRPL39,QARS,PPA2,IARS2,QRSL1,POLG2,PPA1,TARS,CARS2 |
| 2.608e-03 | -5.95 | MAYBURD_RESPONSE_TO_L663536_DN | MSigDB lists | MAYBURD_RESPONSE_TO_L663536_DN | 51 | 16 | 17377 | 2626 |
ZNF207,CCNC,MRPL42,AMD1,TUBGCP5,EZR,RPL15,CYCS,ADPGK,KPNA1,C4orf3,DDOST,MSH2,PPA2,ACTB,OSGEPL1 |
| 2.611e-03 | -5.95 | PGK1 (phosphoglycerate kinase 1) | protein interactions | 5230 | 97 | 27 | 17029 | 2761 |
HSPH1,CYLD,EWSR1,TKT,LDHA,BRCA1,PKM,MCM2,FOXO3,ISG15,HNRNPA2B1,PCNA,PSMA6,HUWE1,DDA1,UBA5,ZNF746,SH3GLB2,H2AFX,AKR1B1,YWHAZ,TAGLN2,FUS,ATP5F1A,CDK2,NIPSNAP2,LDHB |
| 2.614e-03 | -5.95 | Cdc20:Phospho-APC/C mediated degradation of Cyclin A | REACTOME pathways | R-HSA-174184 | 73 | 22 | 10287 | 1696 |
PSMA8,PSMB7,PSMA1,ANAPC2,CDC23,PSMD9,PSMB9,PSMB3,PSMC4,PSMD2,PSMA6,CCNA2,CDC16,PSMD1,CDC27,RPS27A,PSMD8,PSMD3,ANAPC7,UBE2C,PSMC1,ANAPC4 |
| 2.615e-03 | -5.95 | GSE17186_CD21LOW_VS_CD21HIGH_TRANSITIONAL_BCELL_DN | MSigDB lists | GSE17186_CD21LOW_VS_CD21HIGH_TRANSITIONAL_BCELL_DN | 192 | 44 | 17377 | 2626 |
UBL3,IVNS1ABP,MDH2,XIAP,TKT,SDF2L1,PMF1,POMP,B4GALT4,OAT,TCF19,NCAPG,STMN1,CHKA,CDKN2C,SLC31A1,RAP1A,ASAP2,VASP,CCNA2,TBC1D22A,SLC44A1,PRC1,BRI3,MOB1A,TGFB1,CLPTM1,ARHGAP17,ERMP1,ACP2,BIRC3,AURKB,SMC2,TFEB,ATAD2,GOLGA7,WDR11,CORO1C,CEP55,SEL1L,RBPJ,CCNB2,STARD3NL,S100PBP |
| 2.615e-03 | -5.95 | GSE17721_CTRL_VS_CPG_6H_BMDC_DN | MSigDB lists | GSE17721_CTRL_VS_CPG_6H_BMDC_DN | 192 | 44 | 17377 | 2626 |
KARS,PKP4,TRIP12,MECP2,TAP1,PLAGL2,CHIC2,EBNA1BP2,AGFG1,PNO1,PHC2,KRI1,SLC31A1,ATP6V0B,HOMER1,EIF2S2,AHCTF1,SHC1,CBWD2,MECR,PTPN11,H2AFY,TRA2B,MRPL54,PLCL2,ALDH18A1,LRRC59,TIPARP,MORC3,ILF3,WBP2,RAB3IP,FAM50B,DDX39A,DHX15,PSMC4,TRIM26,PPP2R5A,ETS2,CLK3,ITGB1,CD81,IGBP1,NMD3 |
| 2.615e-03 | -5.95 | GSE23308_WT_VS_MINERALCORTICOID_REC_KO_MACROPHAGE_CORTICOSTERONE_TREATED_DN | MSigDB lists | GSE23308_WT_VS_MINERALCORTICOID_REC_KO_MACROPHAGE_CORTICOSTERONE_TREATED_DN | 192 | 44 | 17377 | 2626 |
PRPF38B,CDS2,MAPRE1,GMFG,DYNLL1,STRN4,RLF,LYN,GTF2F1,SEC11A,NEK6,IARS,ARPC5,SH3BP1,ATG3,ZNF639,PIN1,ETV6,TANK,CAPZA1,FOXN2,TRA2B,SEPT11,NOL12,SAMD4B,NXT1,NCK1,IDH3A,PSPC1,MTMR6,GORASP2,SEPT7,STK17B,TARS,NECAP2,EPRS,PROSER1,ITGB1,ARAP1,RWDD4,SLC16A1,RNF14,AP2S1,BYSL |
| 2.615e-03 | -5.95 | GSE1925_3H_VS_24H_IFNG_STIM_IFNG_PRIMED_MACROPHAGE_UP | MSigDB lists | GSE1925_3H_VS_24H_IFNG_STIM_IFNG_PRIMED_MACROPHAGE_UP | 192 | 44 | 17377 | 2626 |
TMEM106C,MAPRE1,AGRN,SUCLG1,CASP6,PTTG1,MCCC1,KLF13,CSNK2A1,PTP4A3,ABCB10,PAWR,IKBIP,COMMD5,GSTK1,ATP6V0B,TBC1D14,SLC44A1,UBA5,RAB4A,AXIN2,KIFAP3,TAGLN2,SLC26A2,RNF19A,ZRANB1,SGCB,SRPK2,LDHB,KLF10,HARS,SIGMAR1,PPP1R21,JTB,MCL1,GFER,MAGED2,NEK1,ACYP1,WNT5B,PKD2,PLOD3,RNF14,TSEN15 |
| 2.615e-03 | -5.95 | GSE2770_IL12_AND_TGFB_ACT_VS_ACT_CD4_TCELL_48H_UP | MSigDB lists | GSE2770_IL12_AND_TGFB_ACT_VS_ACT_CD4_TCELL_48H_UP | 176 | 41 | 17377 | 2626 |
COMMD10,SART1,TXN,KIAA0100,PPP1R15B,MCCC1,TKT,ENSA,CUTC,SNAPC4,REEP5,EEF2K,MAT2B,THADA,INTS7,ETV6,TTC9C,AKR1B1,ZC3H3,MLST8,RPAP3,PPP1R9B,TSTA3,SNRPB,EMB,NUTF2,ECH1,STOML2,UBTF,INF2,MRPL2,IDE,PSMD3,PKD2,SCARB1,GPI,PIEZO1,NANP,REEP4,MAPK1,PITRM1 |
| 2.615e-03 | -5.95 | GSE8921_UNSTIM_VS_TLR1_2_STIM_MONOCYTE_6H_DN | MSigDB lists | GSE8921_UNSTIM_VS_TLR1_2_STIM_MONOCYTE_6H_DN | 176 | 41 | 17377 | 2626 |
DDX58,SKA3,CYLD,GNPDA1,B4GALT5,C19orf25,MOGS,RRM1,C5orf30,DHX8,NUF2,NANS,MFSD10,ABHD16A,CDK5,CCP110,PRC1,KIFAP3,RNF135,TMBIM1,RNLS,ACSL5,PLK3,MAPRE2,TK1,RAD51AP1,CCDC34,MAP7D1,UBE2V1,EXOSC9,IL12RB1,GINS4,MASTL,RAD51C,RBM47,SPATA2,RBL1,DBI,SLC25A19,KPNA2,FAM72A |
| 2.615e-03 | -5.95 | GSE31082_DP_VS_CD4_SP_THYMOCYTE_UP | MSigDB lists | GSE31082_DP_VS_CD4_SP_THYMOCYTE_UP | 176 | 41 | 17377 | 2626 |
H2AFZ,NDUFB6,POC1A,TRIM11,TRAK1,C5orf30,CBLL1,PAIP2,KIF5B,RAB21,SMC3,MEX3C,CCP110,BRPF3,TBC1D22A,PPIL2,FEM1B,CTDSP2,SMC4,DCTN1,GINS1,KDM3B,PDPK1,POLR2I,PSRC1,KRAS,CDCA2,HAUS8,RPA1,CDKN2AIPNL,OSBPL11,HNRNPH3,UHRF2,HMGB2,MRFAP1L1,ACADM,BRD9,OAZ1,MRPL3,ZC3HC1,TUBB |
| 2.615e-03 | -5.95 | GSE9006_TYPE_1_DIABETES_AT_DX_VS_1MONTH_POST_DX_PBMC_DN | MSigDB lists | GSE9006_TYPE_1_DIABETES_AT_DX_VS_1MONTH_POST_DX_PBMC_DN | 176 | 41 | 17377 | 2626 |
NOP2,GMFG,ABCC10,DCTN2,MCCC1,RPL15,COX4I1,ITGB5,TTF1,C2orf68,CDKN2C,ANKRD26,DST,EIF2S2,TNPO2,TNPO3,RPL19,TFG,METTL9,EIF5,IFT46,TPCN1,PDPK1,TIMM8B,SUGP2,CBFA2T2,CCNF,GFER,PFDN5,SERF2,HINT1,SLC38A7,DUSP3,TULP3,MPV17,RBMS1,MDH1,SMAD1,RUFY3,IGBP1,USP13 |
| 2.615e-03 | -5.95 | GSE27786_LSK_VS_NEUTROPHIL_UP | MSigDB lists | GSE27786_LSK_VS_NEUTROPHIL_UP | 176 | 41 | 17377 | 2626 |
UNK,UCK1,INO80E,IFT27,GLRX3,RCOR3,METTL3,MYEF2,HMG20A,MRPL50,CAPN2,GSTK1,ZNF260,MECR,HADHB,TAP2,TTLL12,C12orf75,GINS1,RAD51AP1,DCAF8,NOL8,TEX10,LDB1,TUBGCP5,SCFD2,FAM133B,BRCA1,LRRC1,LUC7L,IWS1,GNAS,ZNF180,MRPL2,DUS3L,DGCR8,HAGHL,PPM1G,C11orf1,MZT2B,POT1 |
| 2.615e-03 | -5.95 | GSE37534_UNTREATED_VS_PIOGLITAZONE_TREATED_CD4_TCELL_PPARG1_AND_FOXP3_TRASDUCED_UP | MSigDB lists | GSE37534_UNTREATED_VS_PIOGLITAZONE_TREATED_CD4_TCELL_PPARG1_AND_FOXP3_TRASDUCED_UP | 176 | 41 | 17377 | 2626 |
MECP2,YTHDC2,PLAGL2,CLCC1,AP1B1,BECN1,RCOR3,FANCI,MIS12,SAC3D1,GSDMB,DNAAF2,KIF14,PDCD2,MCMBP,TACC3,SRSF10,BRD4,MIOS,ZNF202,MRS2,MYBL2,SMC2,AMDHD2,ASB13,CCNF,STK17B,SF3A2,PLEKHF2,CYB5A,NMT2,AKAP1,NIP7,DCK,CCDC69,TCOF1,ARRB2,ZMAT3,POT1,ADNP2,SMARCD1 |
| 2.619e-03 | -5.94 | E2F_WHTH_DNA-bd_dom | interpro domains | IPR003316 | 11 | 6 | 18492 | 2768 |
TFDP2,E2F2,E2F4,TFDP1,E2F1,E2F3 |
| 2.619e-03 | -5.94 | WWE_dom_sf | interpro domains | IPR037197 | 11 | 6 | 18492 | 2768 |
PARP12,TRIP12,HUWE1,TIPARP,ZC3HAV1,DTX4 |
| 2.621e-03 | -5.94 | mTOR signalling | REACTOME pathways | R-HSA-165159 | 39 | 14 | 10287 | 1696 |
TSC1,PRKAB1,TSC2,AKT2,PRKAA1,LAMTOR4,LAMTOR3,CAB39,RRAGC,STK11,AKT1S1,RHEB,MLST8,EEF2K |
| 2.621e-03 | -5.94 | G1 Phase | REACTOME pathways | R-HSA-69236 | 39 | 14 | 10287 | 1696 |
PPP2CA,CDKN2C,RB1,RBL1,RPS27A,E2F4,TFDP1,E2F1,E2F3,CUL1,CDKN1B,TFDP2,E2F2,CDKN2A |
| 2.621e-03 | -5.94 | Cyclin D associated events in G1 | REACTOME pathways | R-HSA-69231 | 39 | 14 | 10287 | 1696 |
PPP2CA,CDKN2C,RB1,RBL1,RPS27A,E2F4,TFDP1,E2F1,E2F3,CUL1,CDKN1B,TFDP2,E2F2,CDKN2A |
| 2.639e-03 | -5.94 | Recruitment of mitotic centrosome proteins and complexes | REACTOME pathways | R-HSA-380270 | 82 | 24 | 10287 | 1696 |
PLK1,FGFR1OP,MAPRE1,DYNLL1,DCTN2,TUBGCP5,HAUS4,CCNB1,CDK11B,PRKACA,CDK11A,HAUS2,TUBGCP2,HAUS8,PCM1,CCP110,CENPJ,ODF2,SSNA1,CEP63,NDE1,TUBB,CSNK1D,DCTN1 |
| 2.639e-03 | -5.94 | Centrosome maturation | REACTOME pathways | R-HSA-380287 | 82 | 24 | 10287 | 1696 |
PLK1,FGFR1OP,MAPRE1,DYNLL1,DCTN2,TUBGCP5,HAUS4,CCNB1,CDK11B,PRKACA,CDK11A,HAUS2,TUBGCP2,HAUS8,PCM1,CCP110,CENPJ,ODF2,SSNA1,CEP63,NDE1,TUBB,CSNK1D,DCTN1 |
| 2.640e-03 | -5.94 | cell activation | biological process | GO:0001775 | 1025 | 188 | 17256 | 2622 |
ADA2,RAB14,ADAM10,KMT2E,HEXB,NHLRC3,GYG1,MAPK14,CMTM6,KCMF1,PA2G4,PSMD1,RAP1A,AP1M1,TXLNA,PLCL2,KCNAB2,BAK1,SP3,ERCC1,EXOSC6,NRAS,NCK1,ARHGAP45,CYSTM1,SOX4,CBFB,RAB5B,STOML2,HHEX,WAS,AGPAT2,ITGB1,CAB39,ADAM9,ATP6V0C,STK11,ACTB,CLU,ROCK1,ARRB2,CAPN1,SVIP,DNAJC5,GMFG,HLA-E,VAV2,LAMTOR3,ASAH1,B4GALT1,CDK13,MAN2B1,EIF2AK4,RAB6A,NOTCH2,PPP3CB,DOCK11,PSEN1,TMEM179B,GNS,CD59,FKBP1A,ARPC5,KIF13B,CTPS1,MSH2,BCL2,OSTF1,MVP,LPCAT1,KDELR1,CYFIP1,FTL,CREG1,MFNG,ITM2A,C1orf35,PKM,ARMC8,CCT8,RHOB,PI4K2A,CAND1,XRCC5,GNAS,CAT,TSC1,SNAP23,ACLY,CEBPG,YWHAZ,CTSA,GPI,RHOG,SNX27,KARS,CYLD,RAF1,DYNLL1,RAC1,MYH9,NIT2,LYN,CPNE3,APP,VAV1,BRI3,CORO1A,F2R,TMBIM1,GM2A,CPNE1,ENPP4,CCT2,TIMP2,RAB7A,SELPLG,PPIE,PSMB7,LRRC8A,ATP6V0A1,DCLRE1C,CADM1,AZI2,TOLLIP,ALDH3B1,DSN1,SURF4,DDOST,RAB24,STAT6,PSMD3,CANT1,TICAM1,PDXK,MAPK1,LTA4H,SMAD4,TUBB,MIF,GCLM,MANBA,PDAP1,TCF3,BTN3A1,JMJD6,IL21R,DNAJB9,FZD6,FERMT3,PTPN2,IRF4,PSMD2,CTSS,HUWE1,PTPN11,CNN2,STAT3,MSH6,SPTAN1,PDPK1,TGFB1,PPP3CA,MLEC,ADAM17,RHOA,CSRP1,PRKDC,HEBP2,KLF6,NEU1,FADD,PRDX1,MAPK3,HSPA1B,GNA12,RAB18,ATP6V1D,MAGT1,GOLGA7,GPS2,SNAP29,PGRMC1,IMPDH1,RBPJ,PSAP,PGAM1,IGBP1 |
| 2.645e-03 | -5.93 | nucleic acid phosphodiester bond hydrolysis | biological process | GO:0090305 | 278 | 60 | 17256 | 2622 |
CHD1L,AGO2,PMS2,TATDN3,LACTB2,SND1,PARN,POLR3K,RRP36,EDC3,KRI1,RPA2,ANKLE1,PCNA,EXOSC7,PPP1R8,PELO,XPA,POP7,RNASEK,DCP1A,RNASEH2A,CNOT6L,CPSF4,ERI3,ZNRD1,GTF2H2,ZC3H3,N4BP2,OGG1,RPP25,TDP1,ERCC1,POLR2I,RFC3,RBX1,POLK,TRIR,BMS1,EXOSC9,DCLRE1C,RFC2,RPSA,RPA1,UTP20,KPNA1,POLE,DGCR8,RPS27A,TATDN2,LRPPRC,AEN,HMGB2,CNOT6,RNASEL,RRS1,TATDN1,GEN1,TSEN15,DDB1 |
| 2.646e-03 | -5.93 | GTCTTCC,MIR-7 | MSigDB lists | GTCTTCC,MIR-7 | 155 | 37 | 17377 | 2626 |
TCF12,DNMT3A,RAF1,FAM53C,PCSK7,PLXNA1,TFRC,UBLCP1,ADCY9,CAPZA1,LTN1,ZBTB22,CRY2,LRRC59,ARID4A,CGGBP1,OXR1,LRRC8A,ATXN1,MIER2,PPFIA3,SRSF5,PLEC,VDAC1,HERPUD2,SERP1,PATL1,ARF4,MKNK1,OSBPL11,SPATA2,CHD3,MAP4,FAM83D,OGT,SMARCD1,RNF114 |
| 2.651e-03 | -5.93 | RNA_POL_M_15KD | prosite domains | PS01030 | 3 | 3 | 12060 | 1670 |
POLR2I,ZNRD1,POLR3K |
| 2.654e-03 | -5.93 | KINESIN_MOTOR_1 | prosite domains | PS00411 | 41 | 13 | 12060 | 1670 |
KIF5B,KIFC1,KIF2A,KIF3B,STARD9,KIF18A,KIF18B,KIF14,KIF13B,KIF23,KIF22,KIF2C,KIF11 |
| 2.656e-03 | -5.93 | JUBAN_TARGETS_OF_SPI1_AND_FLI1_DN | MSigDB lists | JUBAN_TARGETS_OF_SPI1_AND_FLI1_DN | 84 | 23 | 17377 | 2626 |
MIF,TGFB1,FYTTD1,NASP,SEPT9,KAT2A,DDX24,SNRPB,LDHA,S1PR2,CCNB1,CHD1,RAB18,NFATC3,ZNF777,SYNCRIP,NIP7,MBD2,WDR4,BUD31,NAA50,AHDC1,TUBB |
| 2.664e-03 | -5.93 | stomach-carcinoma-adenocarcinoma | COSMIC cancer mutations | stomach-carcinoma-adenocarcinoma | 15615 | 2363 | 17385 | 2587 |
HECA,ZBTB10,ABCC10,HEXB,TGOLN2,CCNL2,FBXO22,EEF2K,THAP4,RAD23B,ATP13A3,DNM2,ZNRD1,FTSJ3,USP34,CCDC57,ERCC1,NRAS,EHMT1,KIF15,HNRNPF,WDHD1,MIER2,DIDO1,MCM2,RAB22A,SMAD2,MID1IP1,RPS27A,MYO18A,OGT,MPV17,SMAD1,ZNF75A,ANXA11,ZNF720,SEC61G,GGA1,MUM1,CCZ1,TRIO,CUTA,RAB23,KCTD17,HAUS4,EIF2AK4,APH1B,PARN,CDC73,MYL6B,ATG4A,TMEM179B,PDXP,SMC3,GEMIN4,MVP,NUP85,PPP6R1,PABPC1,NSUN4,PPA1,IFRD1,AGGF1,FOXK1,RBM42,GTPBP4,MAP7D1,MRPL16,ELK1,EIF4H,RDH11,MAGED2,KPNA1,ETS2,TYW5,WIPI2,RUFY3,PDLIM5,ACSF2,RHOG,EXOC3,STARD7,VTI1A,C5orf30,INO80E,SLC35B2,LCLAT1,RCOR3,CPNE3,KIAA1147,RBM23,ZNF420,AHCTF1,TBC1D22A,TBC1D14,GMEB1,NSFL1C,SEPT11,ZNF226,GPD1L,ZC3H3,ARL5A,PDCL3,SNX8,ERMP1,IDH3A,HTATIP2,MEF2D,TMEM147,GSTCD,TANC1,MAT2A,VPS26B,NSMCE2,CORO1C,CAMKMT,PPP5C,PITRM1,TUBB,COMMD10,ZNF445,HABP4,CCM2,FLOT1,BTN3A1,ATG2B,ABHD14B,PPP1R3B,GOLM1,ZBTB45,HUWE1,ZNF260,NAA50,ANXA5,LTN1,UBE3B,NAP1L4,ZNF710,ST8SIA2,RPL22L1,SPTAN1,STAU1,TCTEX1D2,DDX24,TACC1,MRS2,LDHA,HEBP2,RAB3IP,TTC33,PICALM,SH3BP5,SLC19A1,ACOX1,FAM3C,AEN,PARP10,YWHAH,THAP5,GPATCH4,FAM129A,TRIM11,YTHDC2,SNX15,RBM8A,SND1,RUFY1,TRIM65,ZER1,PRNP,KRR1,RAB8A,NUP210,NT5DC1,NOC2L,EIF5,TACC3,VPS13B,PTPN18,MIOS,SNRPB,MBLAC2,CDC6,UTP3,PBRM1,ODC1,USP21,TRAM2,FBXO28,BCL7C,ARRDC1,ADAM9,DVL1,NUMB,ZNF564,C1orf74,CTU2,PARP12,ZCCHC9,CENPF,CHCHD2,NCKAP1,RSAD1,TNS3,SUB1,RINL,SSBP3,KIF13B,MBD2,XPA,AHCY,RBM3,GLE1,MRPL48,LRSAM1,HDHD2,NTPCR,NSDHL,AMD1,CAMSAP1,ZNF761,METTL22,ICAM2,STYXL1,APPL1,BBS12,ANKRD46,RXRB,SDHB,PCM1,GALNT2,TMEM168,NLRC5,RUVBL2,BTBD10,MYO9A,CCNB2,USP7,GLT8D1,RPLP2,SUCLG1,ARID2,TMX4,SLC2A1,ATP6V1B2,PCBP1,LYN,VAV1,TMEM69,MRPL50,PSMA6,ZNF473,ZNF302,BRPF3,TARDBP,BCAP29,CTDSP2,PRPF19,PPIF,KDM3B,MND1,CLCN3,BIRC3,RAB7A,ANKRD33B,PPIE,CHMP2B,VDAC1,EIF3H,TMEM201,GLOD4,IDE,DHX16,UHRF2,CHMP4B,XRCC3,PARD3,BCL2L12,MCM10,C19orf53,KLHL21,PDAP1,CDCA8,TMX3,ARF1,SLC12A9,TUBGCP2,DNAJB9,HOMER1,POLR1B,RNF5,RBM15B,PPAN,RHOA,RPRD1A,BTAF1,TOP3A,ARHGEF12,PCGF1,DDX23,RAB18,CACNB1,TRIM26,PDCD6,ATP6V1D,L3MBTL3,FAM110A,NEIL3,CTBS,BBX,IMPDH1,TAF12,NR2F2,HIPK3,IFI16,TXN,NUP188,H2AFZ,PNISR,TMEM203,PRKCSH,USP39,UBE2I,SLC25A37,ASPHD2,ZNF428,RAB4A,TRA2B,SUCLG2,TAF5L,ZNF800,CDC5L,ZNF524,SGCE,OSBP2,NSUN2,USP22,CLNS1A,EIF3A,ZMYM3,DOT1L,IWS1,ANKRD10,WAS,KIF18B,TPP2,C1orf109,ZMAT3,B4GALT2,PRPF38B,RECQL,C9orf78,EWSR1,RRM1,ACAP1,B4GALT1,FAM136A,SUPT7L,TMEM165,NPLOC4,CNOT3,SPAG5,WDR48,RTKN,CEP104,EXOSC7,KLHL5,LRRC8D,MSH2,PIGG,OSTF1,FBXL7,MRPL40,TNRC18,FAM171A1,APOL1,EIF5A,GCC2,PRIM2,ELL2,RDH10,MFNG,RPS24,GORASP2,ADRB2,CCT8,MTR,PHF6,PFDN5,SLCO4A1,TTC13,GOLGA2,RBMX,MED15,PIAS2,APPL2,SAMD8,NUDT3,CDKN2A,ZNF511,ATXN3,RAF1,KIAA0232,C2orf49,EPM2A,CD320,CCNA2,MTMR4,TP53BP2,AQR,RBM12B,ILKAP,CDK12,SAP30,BRD4,DRAP1,NARF,LRRC8A,ELP4,ABHD11,PKMYT1,ASB13,TRIM28,SUPT16H,EIF3K,CHMP4A,CBWD1,ATF6,XRCC4,ADAM23,PRPF4B,NDUFS1,DEPDC1,MECP2,SECISBP2,HMG20A,WWP2,JAKMIP1,SLC25A36,CCNK,DNAJC8,ELP5,AXIN2,CITED2,JMJD4,KAT2A,TMEM126B,RABIF,ADSL,PACS1,BMS1,KCNQ1,OTUD3,ARSK,MACF1,KIF11,KLF6,COMMD4,SMAP2,SH3GLB1,MYO1F,TMEM127,INF2,PPP1R11,DUSP11,DDX5,WDR62,TAF6,ESPL1,PURA,DDB1,DEF6,FAM83G,IPO4,UBL3,NAT9,PIGM,LYRM4,GPR132,UBE2Q1,PTP4A3,BRIX1,MRPL19,ZNF696,SF3B2,PCYOX1L,CDC42,SYNM,GOT2,JAZF1,HADHB,RPF2,SLC35C2,CNNM3,CARM1,SRPK2,WDR41,LARS,ZCCHC10,CCDC138,LRBA,TMEM216,SUMF2,KMT2C,OGFR,PRPSAP1,ASF1B,RPL37,MAN2A2,EIF4ENIF1,U2SURP,MIA2,ZNF268,VPS4A,PPP1R2,PM20D2,XPNPEP3,RGS2,LYAR,FAM89B,POLR2I,TRAFD1,SUGP2,GBA,EIF2A,SYVN1,DAPK3,ARHGAP15,MASTL,UAP1,NFIL3,FN3KRP,YWHAZ,CTSA,TOB1,ADNP2,TCF12,PRKAB1,MDH2,SMARCA4,ORC1,RRN3,UBXN2A,IARS,CD3EAP,KIF14,EXOSC1,CS,CLTB,DNAL4,CSTF1,POU2AF1,UBQLN4,NXT1,HPDL,PGGT1B,SELPLG,SMU1,ATXN1,GLO1,OGDH,BICD2,CADM1,EDEM2,HERPUD2,TOLLIP,FANCE,MBD3,PDHX,RPS9,ALKBH6,SURF4,DUS3L,ARNTL,ANP32E,FKBP5,TMEM101,CCDC125,ABCA1,PDCD2L,GCLM,RAE1,DCTN2,NUP54,CHIC2,MXD4,DCUN1D4,PIP4K2A,XPR1,FERMT3,KIF5B,KLHL20,SEC24C,RRBP1,ARHGEF2,ANP32A,LDLRAD3,STAT3,MYO5A,NIPAL3,TXNL1,PHF20L1,DCAF6,FAM49B,TMEM39A,ATP2C1,RFFL,COG1,RCOR1,PRMT2,TFEB,LEMD2,UPF1,ELMO1,ZC3H7B,DTX4,ZMIZ1,TERF1,HRAS,CCDC93,FGFR1OP,PIGQ,AGPAT1,CNTROB,PPP1R16B,GSDMB,TTC9C,PDS5B,NUP153,SENP1,PGAP2,TMEM115,PLEKHM3,DCUN1D5,PLEKHF2,BRMS1,PWWP2B,TRIM47,WDR11,AXIN1,SMG9,TRIM52,LONP2,NDUFV2,PHF23,CERK,SLC4A2,EZH1,ITGB5,LMNA,MCTS1,DDX56,EIF2S2,SLC38A5,FOXN2,CARS2,PRRC2A,C16orf72,RB1CC1,ZMYND11,PGS1,MYBL2,UHRF1BP1,SRSF5,MPG,MATR3,CYB5A,NCDN,POLR2J,SETD3,TEX30,PTAR1,CNOT6,NDE1,EGLN1,ZNF207,ANKRD27,ABCA3,SARNP,IVNS1ABP,MON1B,RMI2,TMEM97,NIT2,NUF2,ZNF267,TCF19,TMEM161B,KTN1,APP,PRKD3,CLUAP1,ATP2A2,UTP18,GRSF1,DUT,ZCCHC2,ANAPC7,RNF19A,FAM76B,CLN6,TMEM9,GCC1,RNF169,ADCY7,ATP6V1G1,ENPP4,CDCA2,FKBP3,GPR137,DDX17,CHCHD3,PEX5,CDC16,HIPK2,MBOAT1,TICAM1,PDXK,ZBTB11,ANXA6,TMBIM4,GMCL1,UBE4A,ETS1,WRB,ZNF92,PNO1,CAPN2,ADD3,SUV39H2,TTLL12,TPCN1,TMX1,HNRNPM,MFSD12,LDHB,PPP3CA,POLK,JTB,EMP3,MTMR12,ZP3,PDE3B,KIF18A,CCDC6,MAPK6,C4orf46,LY75,SLC25A19,RGL1,PSAP,WDR76,IGBP1,FAF1,COX15,AGRN,THOC1,GNPDA1,GPBP1L1,PPP1R15B,CSNK2A1,EBNA1BP2,GIT2,BIRC2,ATPAF1,DLG5,ABL2,XRCC2,ZFYVE27,MCMBP,PTPRK,CDC37,SP3,METTL1,HARS,GMFB,ESYT1,ANLN,RAB5B,RHEB,DPYSL3,TBC1D17,CDCA4,TONSL,NRM,NAGLU,ACTB,ZNF45,TMUB1,CTCF,ASAH1,DOCK11,ASXL2,LRRC14,NUS1,SLC27A4,AFF1,MDFIC,MAML1,CYTH1,NQO2,UTP15,EIF2AK1,EIF4G2,ZDHHC3,MOSPD3,ITPRIPL1,CDC27,SNAP23,TBPL1,PRMT7,KCTD7,CYLD,UGP2,COPE,HCFC1R1,ZADH2,GGPS1,RPAIN,RAD23A,ATP6V0B,PDK2,STRBP,DUS4L,MRPL34,PDCD2,SAP30L,SLC39A9,CLPTM1,RPL29,RPL35,DNAJC9,MTMR6,NFATC2,KDM1B,ARL5B,USP36,CCDC127,MRPL2,ATP1A1,CLK3,PSMD3,CEP55,NDUFA11,DNAJC17,ZNF436,NCOA1,SLC25A39,ZC3HC1,ZNF146,ATXN7L2,CDC40,GOLIM4,SMAP1,DAP,GNE,SMC6,ARFIP2,NKRF,CHAC2,BZW2,WRNIP1,PTGES3,CAMK2G,MLEC,ZNF202,PPWD1,FAM50B,RHOT2,NEU1,TPD52L2,GOLGA7,PGRMC1,GLG1,FAM126A,RPS6KC1,UBE2C,PPCS,NDUFB6,ZDHHC8,PLXNA1,CCNB1,SLC20A1,COMMD6,ABHD14A,POLR3K,ASAP2,SNUPN,CNPY4,PLCL2,TFG,SEH1L,ATG9A,PBK,MKI67,DDX20,AMDHD2,SLC17A5,GALNT7,CCNF,FOXRED1,RBM47,PTER,WDR4,DHTKD1,TRAF5,HDAC2,PWWP2A,HSPH1,MAPRE1,CHTF18,ADO,KIF23,SLC35B1,NOTCH2,PMF1,JMY,FKBP1A,SNX18,CTPS1,ATP6V0A2,PIKFYVE,LPCAT1,EEF1D,TMED2,FTL,PHF10,DDX28,SIGMAR1,PIP4K2C,PLEC,KDM3A,SF3A2,FAS,EPRS,ZNF777,TMEM54,QARS,TCOF1,CABLES1,NRBP1,DNMT3A,RWDD1,CKLF,TRIP10,SF3B1,CAST,SUZ12,RPS6KA1,RAC1,OLA1,SNN,GNB2,FLAD1,APLP2,KDM2A,TNPO2,TALDO1,ATP13A1,RFC3,MAPRE2,ERF,CUL3,SLBP,KIAA1586,H2AFV,GAR1,PSMB9,POLG2,DHX57,NSA2,HSPA4,MRPL55,JAK1,GOLGA8A,TBL3,SEL1L,H2AFX,KLHDC4,B4GALT3,PDCD11,ATMIN,POLQ,POU3F2,OTUD5,NCOR2,ANKRD13D,PKP4,SCAMP3,BABAM1,CDCA3,SLC25A12,BLM,TMCC3,GTF2F1,RPL17,CRAT,AHSA1,PRC1,UPF2,SLC38A10,CNOT6L,CNPY3,UBE2M,IFT46,TSHZ1,ZFP64,STRIP1,DENND4C,DENND1B,WDR18,RPL8,ILF3,LRRC1,RHOT1,TSR2,MARK2,ECH1,PRDX1,PLD3,NUCB1,GNA12,FBXO21,C1orf131,PRDX3,PFDN4,HNRNPH3,TFDP1,STX18,KHSRP,ASNA1,CPEB2,VPS29,BYSL,S100PBP,MIB2,IER2,PTMS,NOP2,UBN1,DCAF15,NF1,FLYWCH2,ALKBH5,MOGS,UBE2Z,TAF6L,MAPK14,BECN1,SNAPC4,RNF103,BCAT2,MBD4,METTL14,IMPAD1,ZNHIT6,RCSD1,PHTF1,SRI,KIF22,ZBTB22,OGG1,TRIM14,ELOF1,COPS8,FYTTD1,TRIM8,RRM2,SOX4,CXXC4,UBTF,PAF1,UEVLD,SPATA2,PQBP1,IARS2,ATXN2L,GALNT10,STARD3NL,PIGN,AGTRAP,CIB1,XPO7,SRRT,ZNF449,CAPZA1,GLTP,BCL2,KIFAP3,N4BP2,HP1BP3,THNSL1,ISG15,CAND1,GNAS,TSC1,RBM25,ZFP90,NANP,RBBP4,ZBTB24,SMARCD1,MBD1,WASF2,MMACHC,TOMM20,IFI27L1,GNPNAT1,MPHOSPH8,HNRNPUL2,CHD1,MEAF6,C2orf68,CCDC50,AKAP8,PARL,RPN2,CHTOP,F2R,FAM3A,SCYL3,ABI1,HTRA2,MOSPD1,RLIM,FAM172A,ZNF500,NLN,WIPF1,BUD13,NDUFB1,PEF1,EIF3G,BTBD1,TAB2,CHCHD1,TULP3,WDR59,CANT1,SCARB1,GAS2,USP11,SMURF1,TSPAN5,PPP2R2D,CDS2,MAGEH1,EYA1,LETMD1,KLF13,RGS1,HDDC2,MAN1A1,FBXO5,GART,TANK,PELO,BRD7,SAMD4B,ZDHHC18,GTF3C6,POLR3GL,WDR81,MEN1,ZNF407,MFN2,ZRANB2,SRSF3,MBD6,IDH3B,TATDN1,ATP6V1C1,TSC2,LACTB2,CMTM6,RBM4,ZNF275,ANKRD39,RPL23A,CDKN2C,NAPG,USF1,DNAAF2,MECR,AP1M1,UPRT,CRY2,ECD,RNF26,TIPARP,LRRC59,ANKRD9,RHBDD2,MGAT5,BAK1,ZNF559,RHOBTB3,GABPA,NUTF2,ARF4,GINS4,KRIT1,AHNAK,RAD18,PDRG1,RNASEL,CHPF2,SMNDC1,PDCD4,NXT2,HIVEP3,KIAA0100,CLSPN,RHOC,DHX9,PDCD7,HAUS2,COPB2,TFAP4,CD59,RNFT1,MEGF8,RIMS3,EFTUD2,FBXO7,CPSF4,MRPL21,PHKG2,LUC7L2,EIF3L,MTA2,TYW1,USP10,ITM2A,SSR2,BCLAF1,SFXN5,FNTA,PDLIM1,TXNDC16,ZNF830,TMEM159,MRPL3,ALS2,TRIM41,KARS,NQO1,POC1A,ANK3,PTTG1,TPX2,TBC1D13,DAZAP2,GLRX3,STMN1,C19orf48,REPS1,ABHD16A,FBXL6,SH3BP1,MTA1,UBA5,CLCN6,INTS12,RPRD1B,SZRD1,CGGBP1,CPNE1,SEC61B,FAM118B,GOPC,E2F3,RPL38,CRNKL1,PFKFB3,GORAB,GIGYF1,TMEM184C,PPP2CA,KIF2A,CCDC14,RNF38,SNRPG,CENPBD1,DMWD,USP13,MZT1,ZFP91,TRMT6,IP6K2,WDR5,SLC25A43,PMVK,NEIL2,RRP36,SRXN1,RPA2,PSMD2,CLIC4,PDCD10,CBWD2,COQ4,ITGB8,ARF5,ARHGEF1,FBXL19,TTPAL,UTP20,MAGT1,GPS2,MRFAP1L1,CD81,TMEM131,WDR13,FANCI,PAPOLA,CREM,FANCL,TET3,GLIS2,IL6ST,INTS1,SLC44A1,MTPN,ASB6,PLK1,RPP25,CELSR2,SEPT9,RBX1,APH1A,RAD51AP1,CKAP2L,PSMG1,UBE2V1,EAF2,IL12RB1,LUC7L,LSG1,NECAP2,ALG3,TRIM4,AGPAT2,CHD3,ZNF367,E2F4,PRPF4,KPNA2,BEND6,CLN3,DNAJC30,FAM208A,NGLY1,POT1,MYL12B,CCDC137,RMND5A,HJURP,PHB2,DNAJB2,FAM53C,NKD2,SDC2,KLC1,CDK13,ADCK5,COX4I1,DNAJB1,RAB6A,ARID1B,C1GALT1,MLX,UBE2Q2,CCP110,ZNF746,ARL6IP1,CTR9,NIPSNAP1,ABHD2,DCAF8,ACSL3,LDB1,MAP4K3,ARMC8,RBM38,NMT2,IRF5,RPL36,HAUS8,MBIP,ORMDL2,COX7A2L,ZDHHC7,SIL1,FAM122A,DTD1,UNC13C,BCCIP,SART1,TRAF7,TOR1AIP1,ZNF416,LAGE3,TM9SF3,ZFYVE21,RRAGC,ZNF121,NRF1,WDR44,PPME1,RPAP1,CABLES2,LMAN1,AHCYL1,TOP1MT,STRAP,SPSB3,ZNF583,SNX25,ARHGAP17,POLR2G,ZNF780B,PPT1,NUP155,DCLRE1C,MRPS14,RHBDF2,SUGP1,RBL1,FASTK,UBXN2B,STK38,AP1S1,SPRYD4,SLC22A23,H3F3A,CHID1,SMAD4,RAD51D,SLC30A9,UNK,CMAS,NADSYN1,HMGN3,NCAPG,SCYL2,FZD6,HERC3,GTPBP3,CTSS,ORC3,RNLS,YTHDC1,ACP2,CSRP1,ABCF2,TUFM,RANGAP1,PNPLA8,HAGH,API5,ZFR,SEC23IP,E2F1,TMEM219,USP20,RBPJ,PDCD6IP,MAX,LUZP1,GXYLT1,ADAM10,CXXC1,TSC22D3,AP3M2,CUL1,GYG1,NANS,OAT,MYEF2,ANKRD26,PA2G4,NOL11,FIZ1,ZNF200,MARCH2,SLC26A2,SRP72,KLF10,LACTB,RFC2,RAB2B,PRIM1,MAP3K4,HHEX,LUC7L3,RPS14,MAP4,MRPL27,BTF3,PTPDC1,NMD3,CCDC59,PTOV1,DNAJC5,DHPS,POLR2K,ANKH,PRKAA1,VAV2,GSPT2,TATDN3,DLGAP4,PXMP2,PRPF39,PSEN1,ZNF79,PDXDC1,NDUFS7,YY1AP1,C12orf10,FAM192A,RPN1,LHX8,ZNRF2,TPST1,DAPK1,PIK3IP1,CYC1,SOCS5,FDFT1,PIGT,EMB,WDR1,ZNF574,C1orf35,EXOSC9,ARID1A,PTTG1IP,C9orf40,FXR1,GOSR1,MAP2K2,TWISTNB,AKAP1,XRCC5,HMGN2,PI4K2A,CAT,DERL1,MTHFD2,HSPBP1,CEBPG,ARAP1,USP32,FAM83D,CABIN1,SMPD4,GPI,CYTIP,TP53RK,REPS2,RAB11B,UROD,SLC39A13,POMP,NUDT19,DECR1,RALB,SIAH1,ADCY9,LPIN2,MRPS27,SOCS6,TTC3,RNASEH2A,CFL1,ANKLE2,CDC123,OAF,EDF1,EML4,ERC1,AMZ2,ANKZF1,ZNF282,DSN1,DDOST,DGCR8,SAFB,HAGHL,FTSJ1,RWDD4,LMBR1,NCLN,BEND3,EYA2,DYNC1LI2,MANBA,B4GALT5,SLC41A1,FAM76A,TKT,CBLL1,ARGLU1,LANCL1,POFUT1,FAM8A1,HEATR5B,HLA-A,EBP,RFWD3,NDUFA2,FJX1,FUT8,BTF3L4,PTPN11,FEM1B,RPL19,CNN2,NDUFA3,MTX2,MSH6,PDLIM2,LONRF3,RFXANK,FBXO9,GUF1,ZHX1,NDUFS5,WDR91,GPR89B,POLA2,ZNF76,MTX3,COPA,UQCR10,PHRF1,ABCB10,COMMD5,MAP1LC3B,DST,RAB35,SIVA1,GPATCH1,TCEA1,DRAM2,DEAF1,TRAPPC13,SNRNP200,LAP3,NCK1,VHL,SREK1,ARHGDIB,PITPNB,HSPB11,BRWD1,PPM1G,SH3GLB2,CRCP,BAZ1B,ACBD4,STK11,CLU,CHEK2,ZSWIM3,TSTD2,MRPL13,CHPT1,DCAF5,CAPN1,UBE2D3,PPP1R12A,ZCCHC8,GORASP1,NACA,UBXN1,RPL15,EPN1,PCSK7,THRAP3,QSOX2,TTF1,PRPF18,NUP205,CHKA,DTL,ZRANB1,SLC12A2,ATP6V0D1,CSNK1G3,RPL6,VKORC1,SLTM,EVC2,KLHL15,SIAH2,SLC16A1,EHD4,SNRNP70,APOL2,N4BP2L2,CHMP2A,CORO7,FEZ2,UCK2,PMS2,UCK1,CLCC1,EXT2,MXD1,USP5,HNRNPA2B1,SAP130,NVL,PPP6C,CYB5R1,ZNF770,EBAG9,RNF25,PCGF6,METTL2A,PON2,HNRNPR,HPS5,STAT6,MAPK1,BRD9,TMEM33,DNAJC2,TRIP12,SHPRH,SCYL1,VPS45,MYO9B,GFM2,SPPL2A,FASTKD3,FGFR3,MZT2A,PPIG,TMEM99,H2AFY,NDUFS8,ATG13,ERI3,FBL,FRMD8,SLC35A1,MICAL3,B3GALT6,TGFB1,ELOVL5,HEMK1,TIMMDC1,HELB,PSPC1,MIER1,SCFD2,NDRG3,CDK11A,MEGF9,ACAT1,CENPT,PLOD3,RAB3IL1,RAB14,ADD1,KDM4A,MRPS15,XIAP,DHX8,GLUD1,ANKRD23,PABPC4,CDK5,CALM2,PSMD1,NEK6,NSRP1,RABGAP1L,SRSF4,FNIP2,KCNAB2,PCBP2,MLST8,PLK3,ZNF672,MRPL43,HSDL1,MCL1,PPFIA3,SMC2,ICMT,SLC50A1,STOML2,LIMK1,ZNF689,PRDX5,ATE1,MLYCD,ST3GAL2,ATP6V0C,FBXL3,TFDP2,E2F2,PFKP,AAAS,DDX42,SSRP1,MRPL9,MRPS2,STRN4,TOP2B,ZNRF3,TMED3,DDRGK1,RAVER2,GNS,INTS7,INPP5A,MCM5,PHF14,ZNF326,NAGPA,TIMM8B,TSPYL4,TSPAN31,DHX29,TEX10,MAN1B1,CBFA2T2,ABCF1,RHOB,LRRC14B,DTWD1,PTPRF,SCARB2,OSBPL11,CCDC86,DUSP3,SLAIN1,MDH1,HEXA,RNF139,SNX14,ZNF296,TRERF1,UBR2,CHD1L,ACTR3,WDTC1,MYH9,NIPA2,PRKACA,SAFB2,ANKIB1,STAM,ARL6IP6,RAB21,SP100,ZKSCAN1,DDA1,NUP107,ANKRD13C,MAVS,CEP63,ATF2,DCTN1,SHOC2,PSRC1,MAP4K4,WBP2,ATP6V0A1,NUSAP1,DNAJA1,TAZ,TAF2,C19orf54,SEC61A1,RPLP1,WDR7,CBLN2,FUS,GEN1,LRP8,COIL,LRCH1,GALK1,ZNF786,RPS2,SESTD1,TRAK1,JMJD6,SIKE1,KRI1,FBXO3,GATC,NDUFB4,PPP1R8,PRDM4,GTSE1,DCP1A,SGCB,S100A6,IMPA2,NUDC,PDPK1,TK1,GUK1,TNFAIP3,GALC,ZNF512,KIAA0930,MRPS10,DDX39A,RPA1,ZNF180,ZNF862,KEAP1,POLE,TATDN2,PITX1,CAPN7,LRPPRC,PML,HMGB2,USF2,ANAPC4,SRM,DDX47,MCCC1,CDC42SE2,S1PR2,CDIPT,SEC16A,SSR1,LIN9,PCNA,ZNF639,TRMU,ETV6,PIK3R2,TXLNA,PPCDC,MYBL1,CCAR1,MRPL32,ABCC5,BAZ2A,PBXIP1,TLK1,MRPL12,EZR,LNX2,LRP5,BRCA1,PRKRA,STX16,EPB41,OPTN,SEPT1,SOCS4,QRSL1,OSGEPL1,GLCCI1,NUDT11,NAA60,GEMIN7,SEPHS2,LZTR1,RACGAP1,PPP3CB,B4GALT4,RLF,RAPGEF6,RB1,VASP,MED8,VMP1,PPIL2,TIMELESS,AHDC1,ALDH18A1,TMEM8A,PREB,ABCC1,TRAPPC9,AACS,MEMO1,KRAS,RTF1,UBE4B,NFATC2IP,LY6E,ARPC1A,ZNF174,PSMC4,GOLGA4,PALB2,SYNCRIP,PRPS2,NIPA1,TIGD2,FOXM1,MRPL39,XAB2,DUSP22,COMMD8,RPL11,CSDE1,MDM2,CORO1A,MINPP1,METTL9,POC5,DVL2,GM2A,PSMA8,COQ10B,CPOX,TIGD5,SLC26A6,CYP20A1,PRPF3,RPSA,SRSF1,DNAJC10,ZNF700,SCAP,PLEKHG4B,TIMM17A,LTA4H,AP2S1,USP53,INTS2,CTDP1,MIF4GD,CDT1,ARID5A,SUMF1,GGA2,CSNK1A1,AP3S1,RMI1,TFRC,PTPN2,STARD9,GSTK1,NDUFV1,SLC1A4,CWC27,SLC35B4,DDX31,ABCD1,RPAP3,CNTN5,SNX2,ZMYM5,CHCHD6,BSDC1,FBXO41,BIRC5,TFE3,SNAP29,CDCA7L,PKD2,ACADM,CHMP7,GCSH,ZNF496,TMEM109,TAP1,YTHDF3,NHLRC3,ELMOD2,KIFC1,DBNDD1,CYB5RL,PARPBP,RNASEK,CDC25B,PRADC1,DNMT1,ORAI2,USO1,AKT2,NOL8,GNG7,AURKB,MCFD2,SLC25A5,ZFAND5,MAK16,STT3A,TMED10,PSMD8,EIF2D,ITGB1,PTPN7,UQCRH,RRS1,ARRB2,RTN3,ZNF598,DDX58,WSB2,MUT,GMFG,HLA-E,MAN2B1,METTL3,CFLAR,NDUFS4,RNF121,MEX3C,KLF16,HDAC7,BDH1,PCYT2,GNAI2,ANKHD1,MORC3,TERF2,KCTD20,SEPT8,DCTD,PKM,TOMM40,PATL1,ADSS,SERTAD2,SERF2,NSF,ERGIC3,ACLY,LPCAT4,VCPIP1,PPP6R3,PPP6R2,MAP3K5,YY1,CDK2,RNF14,ZC3HAV1,SYS1,URB2,EIF3D,MAGED1,KLHL18,ADPGK,SLC25A44,AP1B1,SDHA,PHC2,CRKL,TERF2IP,MOAP1,CYHR1,ZNF75D,SHC1,UCHL5,NAA35,TMBIM1,CCT2,CDKN2AIP,MKLN1,LYRM1,GALK2,CDC23,SHCBP1,AP4E1,PRDM11,VEZF1,PPP2R5A,ACYP1,STAT1,PPA2,TRIM32,RHEBL1,R3HCC1L,C1orf112,TCF3,MRI1,BRAP,AGPAT3,MYNN,SDF2L1,SPR,RAB11A,REEP5,FOXO3,MAD2L2,CCDC28A,PIP5K1C,RBM17,MAT2B,PTEN,CENPJ,TAGLN2,PACS2,NCOA2,SMC4,RNASEH2C,NEK7,NET1,PARP4,TBRG4,ANAPC2,YIF1A,SGSH,HGS,TTLL4,SLC38A7,MFAP1,CCDC69,BRWD3,ESYT2,SKA3,NPHP4,UBE2E2,HNRNPAB,PLXNC1,TMEM184B,ST13,ZNF107,SLC29A1,KIF2C,AGFG1,SIRT2,FKBP2,USP48,SNRPD3,UBQLN2,CUTC,EDC3,ZNF804A,RAP1A,THADA,EIF4A3,DPYSL2,PPP1R12C,AKR1B1,NDUFB9,JOSD1,RP2,TTC4,TECR,ARID4A,FGFR1OP2,TIMM50,TDP1,DPM1,FOPNL,SLC16A7,SLC25A22,STK17B,DHX15,CHAF1A,GEMIN5,COPS6,SASS6,PSMC1,SLC12A7,TBC1D12,TM9SF4,ZNF768,MED13L,TIA1,MEF2A,EPHX2,PITHD1,RHBDD1,NFATC3,BANF1,ZNF335,BUD31,YBX1,KNTC1,ACAD8,UBE3C,ZNF189,ALDH9A1,KDELR1,TSTA3,CIC,OXR1,SEPT7,NAP1L1,NSMF,ODF2,EXOC4,KIAA1328,NUP62,PITPNA,NAA20,PTDSS1,PDSS2,C7orf26,TMEM106C,IMMT,ASH1L,CHERP,WDYHV1,PLAGL2,CHKB,IRF3,TWF2,PAIP1,ANKRD28,ANKLE1,FARSA,SAR1A,SCAMP4,APOOL,PDIA6,ACSL5,TOR1AIP2,AZI2,RAD54B,TMEM41A,DAP3,ZNF317,GADD45B,AKNA,REEP4,CBX4,MIF,KIF3B,GOLPH3L,SH2D3A,CASP6,TOR3A,SRGN,DBF4,MFSD10,SAC3D1,CTNNBL1,YIF1B,CLDND1,TTC17,SLC25A1,GINS1,PAQR6,CSNK1G2,TELO2,ADAM17,NASP,ASPM,PPP1R21,PRKAR1B,SYMPK,TARS,SNRPA,MAPK3,HLA-B,ATAD2,PLAA,ZNF330,OSBPL8,KBTBD7,PREPL |
| 2.665e-03 | -5.93 | positive regulation of type I interferon production | biological process | GO:0032481 | 74 | 21 | 17256 | 2622 |
DDX58,POLR2L,CGAS,POLR2K,PRKDC,DHX9,FLOT1,POLR3GL,IRF3,POLR3K,IRF5,XRCC5,STAT6,STAT1,PQBP1,CRCP,HMGB2,TICAM1,MAVS,RNF135,IFI16 |
| 2.670e-03 | -5.93 | coenzyme biosynthetic process | biological process | GO:0009108 | 170 | 40 | 17256 | 2622 |
GALK1,NADSYN1,PPCS,ADPGK,SPR,MAT2B,FLAD1,GART,COQ4,ATIC,PPCDC,TECR,RNLS,SLC25A1,ACSL5,ELOVL5,ATP5IF1,COQ8A,PPT1,COQ10B,ACSL3,LDHA,NADK2,OGDH,PKM,PDHX,MAT2A,MPC1,ACLY,NAXE,MLYCD,DHTKD1,ACAT1,DHFR2,PDXK,GPI,PGAM1,PARP10,PDSS2,PFKP |
| 2.679e-03 | -5.92 | TCA Cycle Nutrient Utilization and Invasiveness of Ovarian Cancer | WikiPathways | WP2868 | 5 | 4 | 5312 | 837 |
JAK1,STAT3,MAPK1,MAPK3 |
| 2.688e-03 | -5.92 | COTL1 (coactosin like F-actin binding protein 1) | protein interactions | 23406 | 24 | 10 | 17029 | 2761 |
TERF2IP,ACTB,TAGLN2,MCM2,PCBP1,UBE2M,DUT,MDH2,CFL1,TKT |
| 2.688e-03 | -5.92 | TMEM165 (transmembrane protein 165) | protein interactions | 55858 | 24 | 10 | 17029 | 2761 |
SMC3,PPME1,ATP2C1,RPLP1,CUL3,PTAR1,SMC6,UBE4B,WDR62,RPS26 |
| 2.688e-03 | -5.92 | ZEB2 (zinc finger E-box binding homeobox 2) | protein interactions | 9839 | 24 | 10 | 17029 | 2761 |
SMAD2,MTA1,MTA2,COPS6,SMAD1,UBE2I,RBBP4,APP,CBX4,HDAC2 |
| 2.688e-03 | -5.92 | HOXC4 (homeobox C4) | protein interactions | 3221 | 24 | 10 | 17029 | 2761 |
ANKRD28,RABGAP1L,PRKDC,NSD3,ERBIN,LYN,ANKHD1,APP,ELMOD2,XRCC5 |
| 2.688e-03 | -5.92 | IL9R (interleukin 9 receptor) | protein interactions | 3581 | 24 | 10 | 17029 | 2761 |
ZDHHC18,JAK1,TMEM39A,TMX4,SARAF,ABCB10,YWHAZ,UBE4A,TTC17,PDE3B |
| 2.688e-03 | -5.92 | SPTY2D1 (SPT2 chromatin protein domain containing 1) | protein interactions | 144108 | 24 | 10 | 17029 | 2761 |
NIFK,DGCR8,RPS14,RBM34,SCYL1,KBTBD7,KRAS,MRM3,GPATCH4,CENPU |
| 2.688e-03 | -5.92 | RNU12 (RNA, U12 small nuclear) | protein interactions | 267010 | 24 | 10 | 17029 | 2761 |
SNRNP25,SNRNP200,SF3B1,EFTUD2,YBX1,SNRPG,PDCD7,SNRPD3,DHX15,SF3B2 |
| 2.695e-03 | -5.92 | gamma-tubulin ring complex | cellular component | GO:0008274 | 8 | 5 | 18223 | 2701 |
MZT2A,MZT1,BRCA1,MZT2B,TUBGCP5 |
| 2.695e-03 | -5.92 | gamma-tubulin large complex | cellular component | GO:0000931 | 8 | 5 | 18223 | 2701 |
MZT2A,MZT1,BRCA1,MZT2B,TUBGCP5 |
| 2.696e-03 | -5.92 | protein monoubiquitination | biological process | GO:0006513 | 60 | 18 | 17256 | 2622 |
UBE2D3,RBX1,PCGF6,CUL3,CUL1,TOPORS,UBE4B,PCGF1,CDC73,DTL,PAF1,FANCL,RAD18,HUWE1,CTR9,ZNF598,DDB1,RYBP |
| 2.696e-03 | -5.92 | DNA replication | KEGG pathways | hsa03030 | 36 | 13 | 7161 | 1149 |
POLA2,RPA2,PCNA,RFC3,POLE,PRIM2,RNASEH2C,MCM5,RNASEH2A,MCM2,RFC2,RPA1,PRIM1 |
| 2.696e-03 | -5.92 | DNA replication | KEGG pathways | ko03030 | 36 | 13 | 7161 | 1149 |
RPA2,POLA2,RFC3,PCNA,POLE,PRIM2,RNASEH2C,MCM5,RNASEH2A,MCM2,RFC2,RPA1,PRIM1 |
| 2.698e-03 | -5.92 | CCT2 (chaperonin containing TCP1 subunit 2) | protein interactions | 10576 | 251 | 58 | 17029 | 2761 |
HSPH1,CYLD,POC1A,TCF3,ACTR3,GSPT2,VAV2,WDTC1,XIAP,CUL1,SDHA,GNB2,CDC73,SSR1,WWP2,CDK5,RFWD3,PSMD2,SHC1,HUWE1,AHSA1,NSFL1C,CRY2,ATF2,EEF1D,MLST8,NIPSNAP1,CDC5L,MOB4,TXNL1,STAU1,VHL,DCAF8,CUL3,KRAS,BRCA1,DNAJA1,MCM2,CDK11A,CCT8,TRIM28,ISG15,PPP2CA,KPNA4,HSPA4,CAMKMT,DCAF11,ACTB,PRPF4,FUS,WDR76,CDK2,IGBP1,SMURF1,DCAF5,PPP2R2D,TUBB,SSSCA1 |
| 2.702e-03 | -5.91 | negative regulation of cellular macromolecule biosynthetic process | biological process | GO:2000113 | 1402 | 250 | 17256 | 2622 |
RORB,TXN,ZNF496,MAX,H2AFZ,KDM4A,TSC22D3,TRIM11,YTHDF3,SIRT2,UBE2I,RBM4,CREM,CDK5,PA2G4,CIPC,EIF4A3,GLIS2,ZNF639,METTL14,JAZF1,ETV6,NOC2L,CRY2,FNIP2,SMARCE1,DNMT1,ARID4A,RYBP,PTPRK,PLK1,PLK3,SP3,DEAF1,KLF10,AATF,PBXIP1,NCK1,BAZ2A,GABPA,VHL,EHMT1,RIOX2,EZR,DDX20,CDC6,AURKB,BRCA1,DOT1L,PAF1,BRMS1,HHEX,EIF4ENIF1,SMAD2,RPS27A,RPS14,AXIN1,PRDX5,ZNF268,CHEK2,TFDP2,BEND6,POT1,HDAC2,PDCD4,ZNF564,UBE2D3,PHB2,CENPF,CTCF,TIA1,MEF2A,EIF2AK4,DNAJB1,PSEN1,METTL3,CDC73,TTF1,CNOT3,LYAR,TFAP4,RB1,MLX,SMC3,NFATC3,MEX3C,KLF16,MBD2,HDAC7,ZNF746,PHF14,DAPK1,CTR9,TIMELESS,MDFIC,YBX1,MCPH1,TNRC18,TERF2,ZNF189,ETV3,FOXK1,CIC,MTA2,LDB1,GTPBP4,ITM2A,BCLAF1,EIF2AK1,RTF1,ARID1A,CBFA2T2,FXR1,DAPK3,ZNF174,PHF6,XRCC5,TSC1,EPRS,PFDN5,SYNCRIP,ETS2,QARS,NFIL3,ZFP90,YY1,ZNF830,CDK2,TOB1,RNF139,N4BP2L2,CDKN2A,MBD1,ZNF296,DNMT3A,MPHOSPH8,FOXM1,SUZ12,UBR2,MAGED1,WDTC1,SMARCA4,IRF3,DUSP22,RCOR3,MXD1,PAIP2,HNRNPA2B1,SPINDOC,SAP130,ZBTB21,MDM2,SHC1,SP100,CDKN1B,ATF2,RBM15,STRAP,CGGBP1,RLIM,MOSPD1,SAP30,FAM172A,ZNF500,ERF,EID1,BTG2,DRAP1,PCGF6,CIRBP,CUL3,ATXN1,NFATC2,H2AFV,MBD3,TRIM28,CHCHD3,ZNF282,RBL1,HNRNPR,MAFK,HIPK2,STAT6,ARNTL,H2AFX,DNAJC17,STAT1,BEND3,H3F3A,SMAD4,LRP8,CBX4,DNAJC2,UNK,NCOR2,DEPDC1,DAP,MECP2,TCF3,AGO2,ARID5A,PAWR,NKRF,MXD4,BLM,HMG20A,FOXO3,MAD2L2,WWP2,PTPN2,SUV39H2,KMT5A,H2AFY,BRD7,CITED2,CNOT6L,CREB1,STAT3,NCOA2,RBM15B,TSHZ1,TGFB1,SAMD4B,BTAF1,PSPC1,ZNF202,ILF3,RCOR1,ZP3,PRMT2,MEN1,CBX3,CNOT9,UPF1,BIRC5,GPS2,ZHX1,PITX1,E2F1,PML,KHSRP,HMGB2,DDX5,RBPJ,NR2F2,IGBP1,CPEB2,PURA,TERF1,IFI16 |
| 2.704e-03 | -5.91 | regulation of transcription by RNA polymerase II | biological process | GO:0006357 | 2669 | 454 | 17256 | 2622 |
TXN,ZNF496,MAX,H2AFZ,TSC22D3,CXXC1,HEXB,XIAP,CCNL2,UBE2I,MYEF2,PARK7,ZNF275,GLMP,USF1,PSMD1,THAP4,FIZ1,ZNF200,CRY2,FNIP2,ECD,SMARCE1,DNMT1,SENP1,ZNF800,CDC5L,PLK3,ZNF524,ZNF672,ZNF559,KLF10,AATF,GABPA,EHMT1,ELOA,DDX20,WDHD1,MIER2,AURKB,CBFB,ARF4,ZMYM3,DOT1L,BRMS1,HHEX,BOLA3,SMAD2,BRD2,RPS27A,PSMD8,ZNF689,RPS14,AXIN1,OGT,RNASEL,TFDP2,SMAD1,E2F2,ZNF75A,HDAC2,PDCD4,ZNF720,SSRP1,DDX58,HIVEP3,HSPH1,DHX9,EZH1,ZNF79,PSMD9,ZNF518A,PSEN1,CDC73,JMY,DDRGK1,TFAP4,LHX8,KLF16,MEGF8,HDAC7,PHF14,FOXN2,MYDGF,TERF2,ZNF84,ETV3,FOXK1,ZMYND11,MTA2,USF3,ZNF574,MYBL2,EXOSC9,ARID1A,ADRB2,CBFA2T2,C9orf40,ELK1,KDM3A,PSMB3,PHF6,ZNF777,ETS2,ZFP92,EPOP,SETD3,RBMX,MED15,PIAS2,PPP3R1,CEBPG,YY1,RNF14,CDK2,ZNF511,EGLN1,ZNF296,DNMT3A,TRERF1,RWDD1,IVNS1ABP,ZBTB37,RPS6KA1,SUZ12,RAF1,PTTG1,MAGED1,WDTC1,CREBL2,ZNF267,SAFB2,RCOR3,TCF19,APP,AHCTF1,ZNF75D,ZNF420,SP100,KDM2A,ZKSCAN1,MTA1,GMEB1,LPIN2,ZNF226,MAVS,ATF2,RBM15,ZC3H3,RPRD1B,CDK12,CGGBP1,SAP30,BRD4,ERF,EID1,KAT7,DRAP1,WBP2,CUL3,E2F3,ELP4,HTATIP2,MEF2D,PSMB9,TRIM28,SUPT16H,DDX17,TAF2,CHCHD3,VEZF1,ZNF282,CERS6,SAFB,HIPK2,STAT1,ATF6,BEND3,ZBTB11,LRP8,POU3F2,NCOR2,ZNF786,ZNF445,MECP2,ZFP91,TCF3,TRAK1,ABHD14B,MYNN,WDR5,ETS1,HMG20A,FOXO3,MAD2L2,ZNF92,WWP2,GTF2F1,CCNK,ZBTB45,PSMD2,SUV39H2,ZNF260,PRDM4,CARF,CITED2,ZNF710,CREB1,GTF2H2,MED22,NCOA2,TSHZ1,PPP3CA,ZFP64,KAT2A,ZNF512,RFXANK,KLF6,FADD,ZNF180,GPS2,ZHX1,PITX1,TFDP1,PML,DDX5,HMGB2,CD81,BRWD3,IGBP1,USF2,PURA,THAP5,FAM83G,RORB,ZBED3,CCNC,ZNF76,IER2,AGRN,NOP2,AAMDC,UBN1,ZNF107,TAF6L,SIRT2,MAPK14,SNAPC4,ZNF696,CREM,LIN9,TET3,GLIS2,ZNF639,JAZF1,ETV6,PIK3R2,NOC2L,ZBTB22,MYBL1,ARID4A,CARM1,RYBP,PLK1,SP3,DEAF1,RBX1,NCK1,VHL,RIOX2,ZBED5,EZR,LRP5,BRCA1,EAF2,SOX4,PAF1,UBTF,BRWD1,CHD3,E2F4,ZNF367,ZNF268,ZNF45,BEND6,PSMC1,ZNF564,UBE2D3,PPP1R12A,ZNF768,CTCF,CHCHD2,MED13L,MEF2A,CDK13,DNAJB1,PPP3CB,THRAP3,RLF,ASXL2,CRLF3,TTF1,ARID1B,LYAR,SUB1,RB1,MLX,NFATC3,MED8,ZNF449,MED10,MBD2,SSBP3,ZNF746,BUD31,ZNF335,CTR9,TIMELESS,YBX1,MAML1,MCPH1,ZNF189,CREG1,ERLIN1,CIC,LDB1,PSMA1,RTF1,EIF2A,NFATC2IP,SLTM,IRF5,ZNF174,CAND1,RXRB,PSMC4,NFIL3,TBPL1,NLRC5,ZFP90,RUVBL2,TOB1,N4BP2L2,ZBTB24,SMARCD1,ADNP2,TCF12,MBD1,ASH1L,ARID2,FOXM1,ZNF416,SMARCA4,PLAGL2,IRF3,PCBP1,DUSP22,CHD1,ZNF121,MXD1,HNRNPA2B1,SAP130,NRF1,ZBTB21,PSMA6,MDM2,ZNF302,PIN1,TARDBP,STRAP,ZNF770,ZNF583,RLIM,MOSPD1,POU2AF1,ZNF500,PSMA8,BTG2,PCGF6,PSMB7,BOLA1,GLO1,NFATC2,MBD3,ZNF317,RBL1,SCAP,ZNF700,MAFK,PSMD3,STAT6,ARNTL,ZNF436,DNAJC17,NCOA1,AKNA,SMURF1,SMAD4,CBX4,ZNF146,SLC30A9,BCL2L12,DNAJC2,CTDP1,EYA1,AGO2,ARID5A,KLF13,PAWR,GTF3A,NKRF,HMGN3,MXD4,PAGR1,PTPN2,IRF4,KMT5A,PELO,H2AFY,ARHGEF2,BRD7,SS18L1,STAT3,TGFB1,DCAF6,RHOA,RPRD1A,HMGN1,HMGN5,PSPC1,ZNF202,PRKDC,MIER1,ZMYM5,RCOR1,MEN1,ZNF407,MAPK3,TFEB,LEMD2,ATAD2,TWSG1,TFE3,BBX,E2F1,KMT2B,PKD2,RBPJ,CENPT,NR2F2,ZMIZ1,HRAS,TERF1,IFI16 |
| 2.704e-03 | -5.91 | JISON_SICKLE_CELL_DISEASE_DN | MSigDB lists | JISON_SICKLE_CELL_DISEASE_DN | 171 | 40 | 17377 | 2626 |
TSC22D3,SRSF6,TCF3,EIF3D,NACA,TOP2B,SAFB2,SRRT,PABPC4,RPL11,RPL23A,RPL17,MSH2,RPL19,FBL,TGFB1,SNRNP200,SUGP2,CIRBP,RPL6,RPS24,BCLAF1,OTUD3,SRSF5,PDE3B,EIF3H,RPL37,EIF3K,NAP1L1,JAK1,TMED10,RPS27A,RPLP1,OGT,ATXN2L,DDX5,TRIM32,BTF3,SNRNP70,TRAF5 |
| 2.704e-03 | -5.91 | GSE26488_CTRL_VS_PEPTIDE_INJECTION_OT2_THYMOCYTE_DN | MSigDB lists | GSE26488_CTRL_VS_PEPTIDE_INJECTION_OT2_THYMOCYTE_DN | 171 | 40 | 17377 | 2626 |
WASF2,ANKRD13D,GMFG,ADD1,MECP2,CERK,MYH9,GGA2,DOCK11,IL21R,RAPGEF6,C1GALT1,SMC3,ADD3,AP1M1,CORO1A,CITED2,CSNK1G3,TGFB1,PPP3CA,SNX2,MBLAC2,MAP4K4,ATP6V0A1,EMP3,DNAJC9,ARID1A,KLF6,PICALM,SMAP2,ISG15,SH3BP5,AHNAK,JAK1,BRWD1,NRM,RNF38,NCOA1,AKNA,ABCA1 |
| 2.706e-03 | -5.91 | chromatin remodeling | biological process | GO:0006338 | 186 | 43 | 17256 | 2622 |
HJURP,CHD1L,SMARCA4,TAF6L,INO80E,CHD1,HMG20A,ARID1B,OIP5,RB1,SP100,SUV39H2,MBD2,ANP32A,CENPM,TOP1MT,SMARCE1,TNRC18,ELOF1,KAT2A,NASP,BAZ2A,MTA2,RIOX2,PBRM1,ARID1A,MBD3,CENPU,CBX3,UBTF,KMT2B,BAZ1B,ANP32E,ACTB,HMGB2,CENPT,RUVBL2,H3F3A,RBBP4,HDAC2,CDKN2A,SMARCD1,SSRP1 |
| 2.707e-03 | -5.91 | MODULE_480 | MSigDB lists | MODULE_480 | 89 | 24 | 17377 | 2626 |
CYTH1,MIF4GD,ZNF559,SNX2,GALC,ACSL3,DNAJB1,CCNB1,PSEN1,MIEN1,CHCHD6,MAD2L2,HSPA1B,HMGN2,MCTS1,GTPBP3,NUP210,PPP1R11,SIL1,AP1S1,ATE1,GAS2,RNF139,GEMIN7 |
| 2.712e-03 | -5.91 | RPGR (retinitis pigmentosa GTPase regulator) | protein interactions | 6103 | 48 | 16 | 17029 | 2761 |
NPHP4,RHOA,DCTN2,DNAJA1,SMC3,IDE,DNM2,KIFAP3,FAM126A,NR2F2,ORC3,COPS6,TUBB,SPSB3,DCTN1,NUDC |
| 2.712e-03 | -5.91 | ZRSR2 (zinc finger CCCH-type, RNA binding motif and serine/arginine rich 2) | protein interactions | 8233 | 48 | 16 | 17029 | 2761 |
RBM17,SART1,CHERP,SF3B1,U2SURP,GTPBP4,RPL15,JMJD6,SNRPG,PDCD7,CDK11B,TTC33,APP,SRSF1,SF3B2,SRPK2 |
| 2.712e-03 | -5.91 | RSBN1 (round spermatid basic protein 1) | protein interactions | 54665 | 48 | 16 | 17029 | 2761 |
USP7,ZNF512,CXXC1,TEX10,KRAS,CDK11B,PRKACA,UBTF,CDC16,ZNF317,CDC27,RBM34,BBX,ZRANB2,PDCD11,DDX52 |
| 2.712e-03 | -5.91 | KLHL22 (kelch like family member 22) | protein interactions | 84861 | 48 | 16 | 17029 | 2761 |
PLK1,LYRM4,KLHL20,NOA1,UBXN1,TRMT6,CUL3,MICU2,NDUFB9,GLUD1,BRCA1,COPS6,NIPSNAP2,GFER,FAF1,RBM15B |
| 2.712e-03 | -5.91 | DDX46 (DEAD-box helicase 46) | protein interactions | 9879 | 48 | 16 | 17029 | 2761 |
SRSF11,CUL3,RCOR1,JMJD6,SF3A2,LMNA,RPA1,RPA2,GEMIN5,HUWE1,MYO18A,TCEA1,EEF1D,LUC7L2,SRPK2,CDC5L |
| 2.712e-03 | -5.91 | HIVEP1 (human immunodeficiency virus type I enhancer binding protein 1) | protein interactions | 3096 | 48 | 16 | 17029 | 2761 |
MTMR3,CDKN2AIP,NUCB1,IMMT,GSDMB,APH1A,MAGED1,KBTBD7,ATXN1,BRCA1,DNAJA1,RAB1A,STAT3,MAPK14,IRF5,SRPK2 |
| 2.712e-03 | -5.91 | SENP1 (SUMO specific peptidase 1) | protein interactions | 29843 | 48 | 16 | 17029 | 2761 |
SP3,ZNF420,SP100,HIPK2,SUMO2,PML,NUP107,RANGAP1,NUP153,RUVBL2,ARRB2,SENP1,APP,ISG15,LMNA,HDAC2 |
| 2.712e-03 | -5.91 | CD274 (CD274 molecule) | protein interactions | 29126 | 48 | 16 | 17029 | 2761 |
INTS2,NF1,COG1,USP22,XPO7,CIP2A,UTP20,THADA,KIF14,PDS5B,PTPN11,TNPO2,TNPO3,MINPP1,NUP85,TMEM160 |
| 2.714e-03 | -5.91 | GSE8621_LPS_PRIMED_UNSTIM_VS_LPS_PRIMED_AND_LPS_STIM_MACROPHAGE_UP | MSigDB lists | GSE8621_LPS_PRIMED_UNSTIM_VS_LPS_PRIMED_AND_LPS_STIM_MACROPHAGE_UP | 187 | 43 | 17377 | 2626 |
OTUD5,LIME1,NQO1,SLC41A1,TSC22D3,DNAJB2,WDTC1,FLOT1,SAFB2,PIP5K1C,ABHD16A,ZNF428,APLP2,CTNNBL1,EIF4A3,PPIL2,TRMU,SLC44A1,SRI,TECR,ZNF189,CSNK1G2,DCAF8,ZNF512,RPS10,SEPT8,ADRB2,ICAM2,BUD13,VKORC1,DAPK3,SUGP1,DAP3,HGS,AGPAT2,APPL2,NLRC5,PKD2,ZFP90,DDX5,TAF12,DMWD,S100PBP |
| 2.714e-03 | -5.91 | GSE33162_UNTREATED_VS_4H_LPS_STIM_HDAC3_HET_MACROPHAGE_DN | MSigDB lists | GSE33162_UNTREATED_VS_4H_LPS_STIM_HDAC3_HET_MACROPHAGE_DN | 187 | 43 | 17377 | 2626 |
TMEM106C,SLC12A7,CTDP1,PPCS,SLC41A1,DNAJB2,CERK,LANCL1,EZH1,CCNL2,C19orf48,CRLF3,RAPGEF6,TTF1,JMY,CHKA,HUWE1,IL6ST,ZNF746,AXIN2,TTC3,BCL2,TMEM8A,CTDSP2,TIMP2,CIC,CAMSAP1,FRAT2,RAB3IP,CBFA2T2,TANC1,SOX4,MEN1,SLTM,RPS9,TSR2,USP36,FBXO21,FBXO28,AXIN1,APPL2,SMAD1,SMAD4 |
| 2.714e-03 | -5.91 | GSE17721_LPS_VS_CPG_8H_BMDC_DN | MSigDB lists | GSE17721_LPS_VS_CPG_8H_BMDC_DN | 187 | 43 | 17377 | 2626 |
SEPHS2,RPS2,TP53RK,ZFP91,NUP54,TM9SF3,CDK11B,GLRX3,PCBP1,GFM2,PNO1,FBXO22,MRPL50,FKBP1A,NOL11,IARS,SLC38A5,ZNF639,IL6ST,TBC1D14,PPCDC,SLC35A1,RNF5,ERMP1,FOPNL,PRKDC,SEPT8,ARHGDIB,GALK2,WBP1,MCFD2,TARS,CYB5A,BTBD1,CAT,C1orf131,STT3A,GPS2,AEN,KPNA2,LTA4H,RTN3,PDF |
| 2.714e-03 | -5.91 | GSE6259_DEC205_POS_DC_VS_CD4_TCELL_UP | MSigDB lists | GSE6259_DEC205_POS_DC_VS_CD4_TCELL_UP | 187 | 43 | 17377 | 2626 |
HECA,FEZ2,ZNF768,TPX2,CDCA3,TIA1,CNTROB,IKBIP,B4GALT4,TMEM165,SF3B2,FBXO3,RAP1A,PDCD10,CLIC4,CENPJ,LPIN2,ZNF260,NUP107,LTN1,KIFAP3,RNF135,LRRC59,SMC4,PPP1R18,MKLN1,TCTEX1D2,NSDHL,RAB7A,ACSL3,HEBP2,EMP3,CBFA2T2,STK17B,TARS,TMEM168,PFDN4,RBL1,UBXN2B,RNASEL,BTF3,WDR91,PFKP |
| 2.714e-03 | -5.91 | GSE17721_LPS_VS_GARDIQUIMOD_16H_BMDC_DN | MSigDB lists | GSE17721_LPS_VS_GARDIQUIMOD_16H_BMDC_DN | 187 | 43 | 17377 | 2626 |
WASF2,NCOR2,TMED7,GCLM,CKLF,MUT,RRP15,RPLP2,HJURP,DAP,STARD7,MEF2A,RAB6A,STMN1,REEP5,MFSD10,PABPC4,PRNP,ATP6V0B,PSMD2,VASP,ATP2A2,IARS,UTP18,SLC44A1,MECR,ANXA5,TMBIM1,TMX1,S100A6,SRSF11,METTL1,MLEC,FAM49B,BTG2,RPL38,TBRG4,EMP3,STK17B,AHNAK,USP20,AEN,DVL1 |
| 2.714e-03 | -5.91 | GSE43863_DAY6_EFF_VS_DAY150_MEM_TH1_CD4_TCELL_DN | MSigDB lists | GSE43863_DAY6_EFF_VS_DAY150_MEM_TH1_CD4_TCELL_DN | 187 | 43 | 17377 | 2626 |
PLXNC1,AGRN,FAM129A,TCF3,ARID5A,YTHDF3,BCL2L1,MYEF2,CPNE3,CFLAR,TMCC3,BDH1,FUT8,BCL2,TAGLN2,ZRANB1,ZNF710,PIKFYVE,SMARCE1,CARM1,B3GALT6,BIRC3,ETV3,TNFAIP3,KIAA0040,LAP3,MYBL2,CDCA2,USP22,ARID1A,PDE3B,STK17B,LSG1,OPTN,CDC27,PFDN4,GADD45B,NFIL3,BBX,RBMS1,FAM126A,AKNA,CD81 |
| 2.714e-03 | -5.91 | GSE29618_MONOCYTE_VS_PDC_DAY7_FLU_VACCINE_DN | MSigDB lists | GSE29618_MONOCYTE_VS_PDC_DAY7_FLU_VACCINE_DN | 187 | 43 | 17377 | 2626 |
PPIB,SEC61G,TCF3,MAGED1,SLC2A1,TMEM109,SMC6,B4GALT1,TMED3,FKBP2,GGA2,STMN1,PPP1R16B,APP,PARK7,KIF5B,IRF4,SNRNP25,RRBP1,MDFIC,PACS2,TMED2,MAPRE2,SEC61B,DDX24,IDH3A,GNG7,GLO1,CYFIP2,ODC1,RPSA,DDX17,HINT1,TMED10,CERS6,DCK,GOLGA8A,OGT,ST3GAL2,SPCS3,MYO9A,TMEM14A,NGLY1 |
| 2.714e-03 | -5.91 | GSE18281_SUBCAPSULAR_VS_PERIMEDULLARY_CORTICAL_REGION_OF_THYMUS_UP | MSigDB lists | GSE18281_SUBCAPSULAR_VS_PERIMEDULLARY_CORTICAL_REGION_OF_THYMUS_UP | 187 | 43 | 17377 | 2626 |
MIB2,LZTR1,ADD1,RPS6KA1,DAP,TCF3,HABP4,TRIO,CIB1,TMEM109,TOP2B,ABHD14B,MXD4,LANCL1,AP1B1,LCLAT1,PIP4K2A,FAM8A1,GSTK1,NRF1,NFATC3,FAM89B,MSH2,TTC3,SLC12A2,TPCN1,GM2A,SPSB3,ADCY7,PPT1,EMP3,MEF2D,VKORC1,BTBD1,MAPK3,SCARB2,WAS,GLG1,GPI,CLU,MYO9A,HIGD2A,RAB3IL1 |
| 2.714e-03 | -5.91 | GSE10239_NAIVE_VS_KLRG1HIGH_EFF_CD8_TCELL_UP | MSigDB lists | GSE10239_NAIVE_VS_KLRG1HIGH_EFF_CD8_TCELL_UP | 187 | 43 | 17377 | 2626 |
CTU2,AGRN,RPLP2,UBN1,HLA-E,UBR2,HMGXB3,CCM2,ARID5A,KLF13,UBLCP1,RPL11,IL6ST,MEA1,RPL19,PCYT2,CORO1A,PIK3IP1,ZNF710,NCOA2,NTPCR,RHOA,RPL35,SELPLG,RPL38,RPL27A,HAGH,FAS,RPL36,ANKRD10,SH3BP5,RPS14,STAT6,WDR59,COX7A2L,OAZ2,DCAF11,GLG1,DNAJC17,APPL2,MLYCD,DUSP11,SMAD4 |
| 2.714e-03 | -5.91 | VANHARANTA_UTERINE_FIBROID_WITH_7Q_DELETION_UP | MSigDB lists | VANHARANTA_UTERINE_FIBROID_WITH_7Q_DELETION_UP | 65 | 19 | 17377 | 2626 |
UBQLN4,MAX,ZFP64,NXT1,SMARCA4,PAPOLA,PTPN2,VEZF1,FBXO21,RAD51C,TNFAIP8,RAD23B,STX18,TBPL1,ANP32E,TCEA1,RUVBL2,SRSF3,CARS2 |
| 2.714e-03 | -5.91 | PID_BCR_5PATHWAY | MSigDB lists | PID_BCR_5PATHWAY | 65 | 19 | 17377 | 2626 |
PDPK1,PPP3CA,RAF1,VAV2,RAC1,CSNK2A1,PPP3CB,ELK1,MAPK14,LYN,ETS1,MAPK3,SH3BP5,SHC1,CSK,PTEN,MAPK1,HRAS,CAMK2G |
| 2.714e-03 | -5.91 | KEGG_GLIOMA | MSigDB lists | KEGG_GLIOMA | 65 | 19 | 17377 | 2626 |
NRAS,AKT2,RAF1,E2F3,KRAS,MAP2K2,MAPK3,CALM2,RB1,MDM2,SHC1,PTEN,PIK3R2,E2F1,MAPK1,E2F2,HRAS,CAMK2G,CDKN2A |
| 2.714e-03 | -5.91 | OUELLET_CULTURED_OVARIAN_CANCER_INVASIVE_VS_LMP_UP | MSigDB lists | OUELLET_CULTURED_OVARIAN_CANCER_INVASIVE_VS_LMP_UP | 65 | 19 | 17377 | 2626 |
SEPHS2,SRP72,BIRC3,RAE1,GMFB,SLC4A2,CAPZA2,DCUN1D4,RAB11A,QARS,SAFB,SRI,AHCY,NDUFS8,ACADM,RBBP4,GCSH,HNRNPM,LDHB |
| 2.716e-03 | -5.91 | Ribosomal_S5_D2-typ_fold | interpro domains | IPR020568 | 34 | 12 | 18492 | 2768 |
GALK1,EXOSC7,EXOSC6,RPS2,EFTUD2,PMS2,EXOSC9,TOP2B,GALK2,EFL1,GFM2,LONP2 |
| 2.717e-03 | -5.91 | GO_REGULATION_OF_APOPTOTIC_SIGNALING_PATHWAY | MSigDB lists | GO_REGULATION_OF_APOPTOTIC_SIGNALING_PATHWAY | 347 | 72 | 17377 | 2626 |
CYLD,TRAF7,NF1,IVNS1ABP,DYNLL1,RAF1,MAGED1,PLAGL2,BCL2L1,BCAP31,PARK7,MOAP1,RRN3,SP100,SIAH1,SIVA1,NOC2L,PARL,TP53BP2,TMBIM1,HTRA2,ACSL5,BAK1,PPIF,PGAP2,NCK1,VDAC2,MCL1,BRCA1,PRKRA,SLC25A5,TRIM32,CLU,ARRB2,ZC3HC1,MIF,BCL2L12,GCLM,HSPH1,EYA1,PSEN1,LMNA,APOPT1,CFLAR,TFAP4,PTPN2,PTEN,DAPK1,ARHGEF2,FEM1B,BCL2,TNFAIP3,RB1CC1,ZMYND11,RFFL,BCLAF1,SYVN1,PTTG1IP,DAPK3,FADD,HSPA1B,FAS,TFDP1,PPP3R1,E2F1,SIAH2,PML,YWHAZ,HMGB2,IGBP1,YWHAH,FAF1 |
| 2.720e-03 | -5.91 | ATGAAGG,MIR-205 | MSigDB lists | ATGAAGG,MIR-205 | 150 | 36 | 17377 | 2626 |
CCDC93,SNX27,IVNS1ABP,PLAGL2,TM9SF3,NDUFA4,WDR48,PHC2,LIN9,HERC3,SIAH1,MTMR4,BUD31,SEPT11,BCL2,LPCAT1,ZNF800,SEH1L,SRSF10,SRSF5,PDE3B,SLTM,EPB41,VEZF1,MKNK1,MID1IP1,RBM47,DGCR8,LIMK1,SEL1L,E2F1,ACTB,DDX5,CPEB2,RTN3,GPATCH4 |
| 2.722e-03 | -5.91 | protein deacetylase activity | molecular function | GO:0033558 | 46 | 15 | 17224 | 2647 |
BRMS1,CHD3,HDAC7,MTA1,MTA2,MIER1,RCOR1,MIER2,SIRT2,RBBP4,MBD3,SAP30L,ARID4A,HDAC2,SAP30 |
| 2.733e-03 | -5.90 | GSE21033_3H_VS_24H_POLYIC_STIM_DC_DN | MSigDB lists | GSE21033_3H_VS_24H_POLYIC_STIM_DC_DN | 114 | 29 | 17377 | 2626 |
MLEC,GOLIM4,RWDD1,SNX2,E2F3,RACGAP1,ESYT1,GNB2,CDKN2C,MAGED2,ALG3,TPD52L2,PDLIM1,UBA5,XRCC2,COX8A,H2AFX,AP1M1,TIMELESS,SLC16A1,QRSL1,KIFAP3,SLC38A10,RBM3,TCEA1,GM2A,MED22,HIGD2A,ELOF1 |
| 2.734e-03 | -5.90 | PPP5C (protein phosphatase 5 catalytic subunit) | protein interactions | 5536 | 88 | 25 | 17029 | 2761 |
CPNE1,PPIB,PSPC1,ABCF2,TUFM,ABHD14A,APP,BZW2,HSPA1B,PLD3,GNA12,CDC16,HSPA4,CDC27,DUT,AHSA1,CTPS1,CRY2,PTGES3,MAP3K5,MINPP1,PPP5C,TATDN1,CDC37,FUBP1 |
| 2.734e-03 | -5.90 | PKN2 (protein kinase N2) | protein interactions | 5586 | 88 | 25 | 17029 | 2761 |
PDPK1,UNK,KARS,LARS,TMUB1,RHOA,NCK1,ERLIN1,GOPC,MYO9B,RUFY1,EIF3G,KTN1,EPRS,PCM1,IARS,ATP2A2,PTEN,LSM6,CENPJ,AHSA1,BTF3,USP11,EEF1D,CDC5L |
| 2.735e-03 | -5.90 | U4/U6 x U5 tri-snRNP complex | cellular component | GO:0046540 | 26 | 10 | 18223 | 2701 |
SART1,SNRNP200,LSM6,SNRPB,EFTUD2,LSM8,PRPF4,PRPF3,TXNL4A,PRPF18 |
| 2.735e-03 | -5.90 | proton-transporting V-type ATPase complex | cellular component | GO:0033176 | 26 | 10 | 18223 | 2701 |
ATP6V0B,ATP6V1D,ATP6V0A1,ATP6V0A2,ATP6V0C,ATP6V1C1,ATP6V1B2,ATP6V0E1,ATP6V0D1,ATP6V1G1 |
| 2.735e-03 | -5.90 | U12-type spliceosomal complex | cellular component | GO:0005689 | 26 | 10 | 18223 | 2701 |
SNRNP25,SNRPB,SF3B1,SF3B6,YBX1,SNRPG,SNRPD3,PDCD7,DHX15,SF3B2 |
| 2.744e-03 | -5.90 | trichoblastoma | COSMIC cancer mutations | trichoblastoma | 8 | 5 | 17385 | 2587 |
FGFR3,KRAS,CYLD,NRAS,HRAS |
| 2.744e-03 | -5.90 | cervix-carcinoma-small_cell_carcinoma | COSMIC cancer mutations | cervix-carcinoma-small_cell_carcinoma | 8 | 5 | 17385 | 2587 |
RB1,KRAS,NRAS,SF3B1,HRAS |
| 2.744e-03 | -5.90 | actinic_keratosis | COSMIC cancer mutations | actinic_keratosis | 8 | 5 | 17385 | 2587 |
FGFR3,KRAS,NRAS,HRAS,CDKN2A |
| 2.744e-03 | -5.90 | haematopoietic_and_lymphoid_tissue-lymph_node-lymphoid_neoplasm-marginal_zone_lymphoma | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-lymph_node-lymphoid_neoplasm-marginal_zone_lymphoma | 8 | 5 | 17385 | 2587 |
KRAS,NOTCH2,NRAS,TNFAIP3,HRAS |
| 2.744e-03 | -5.90 | endometrium-hyperplasia | COSMIC cancer mutations | endometrium-hyperplasia | 8 | 5 | 17385 | 2587 |
KRAS,NRAS,PTEN,HRAS,MSH2 |
| 2.744e-03 | -5.90 | salivary_gland-retromolar-carcinoma-adenoid_cystic_carcinoma | COSMIC cancer mutations | salivary_gland-retromolar-carcinoma-adenoid_cystic_carcinoma | 8 | 5 | 17385 | 2587 |
KRAS,NRAS,PTEN,HRAS,CDKN2A |
| 2.744e-03 | -5.90 | junctional | COSMIC cancer mutations | junctional | 8 | 5 | 17385 | 2587 |
FGFR3,KRAS,NRAS,HRAS,CDKN2A |
| 2.744e-03 | -5.90 | cervix-carcinoma-endocervical_adenocarcinoma | COSMIC cancer mutations | cervix-carcinoma-endocervical_adenocarcinoma | 8 | 5 | 17385 | 2587 |
GNAS,KRAS,STK11,NRAS,PTEN |
| 2.744e-03 | -5.90 | multihormonal | COSMIC cancer mutations | multihormonal | 8 | 5 | 17385 | 2587 |
KRAS,NRAS,HRAS,AXIN1,CDKN2A |
| 2.744e-03 | -5.90 | skin-neck-malignant_melanoma-superficial_spreading | COSMIC cancer mutations | skin-neck-malignant_melanoma-superficial_spreading | 8 | 5 | 17385 | 2587 |
KRAS,NRAS,PTEN,HRAS,CDKN2A |
| 2.744e-03 | -5.90 | bone-coccyx-chordoma | COSMIC cancer mutations | bone-coccyx-chordoma | 8 | 5 | 17385 | 2587 |
KRAS,NRAS,H3F3A,HRAS,CDKN2A |
| 2.744e-03 | -5.90 | autonomic_ganglia-abdomen-paraganglioma-benign | COSMIC cancer mutations | autonomic_ganglia-abdomen-paraganglioma-benign | 8 | 5 | 17385 | 2587 |
KRAS,NRAS,VHL,HRAS,CDKN2A |
| 2.744e-03 | -5.90 | skin-neck-malignant_melanoma-nodular | COSMIC cancer mutations | skin-neck-malignant_melanoma-nodular | 8 | 5 | 17385 | 2587 |
KRAS,NRAS,PTEN,HRAS,CDKN2A |
| 2.744e-03 | -5.90 | endocervical_adenocarcinoma | COSMIC cancer mutations | endocervical_adenocarcinoma | 8 | 5 | 17385 | 2587 |
GNAS,KRAS,STK11,NRAS,PTEN |
| 2.748e-03 | -5.90 | PID_ECADHERIN_NASCENT_AJ_PATHWAY | MSigDB lists | PID_ECADHERIN_NASCENT_AJ_PATHWAY | 38 | 13 | 17377 | 2626 |
WASF2,RAP1A,RHOA,KLHL20,CDC42,RAC1,VAV2,AP1M1,CSNK2A1,NCKAP1,CYFIP2,ABI1,PIP5K1C |
| 2.748e-03 | -5.90 | GO_NUCLEOID | MSigDB lists | GO_NUCLEOID | 38 | 13 | 17377 | 2626 |
DDX28,GRSF1,LRPPRC,HADHB,VDAC2,TUFM,TOP2B,TOP1MT,VDAC1,MPG,POLG2,SLC25A5,LRRC59 |
| 2.748e-03 | -5.90 | GO_REGULATION_OF_DNA_DEPENDENT_DNA_REPLICATION | MSigDB lists | GO_REGULATION_OF_DNA_DEPENDENT_DNA_REPLICATION | 38 | 13 | 17377 | 2626 |
RFC3,SMC3,CHTF18,CDT1,CHEK2,BLM,ZNF830,CDK2,RFC2,TERF1,TERF2,STOML2,WRNIP1 |
| 2.748e-03 | -5.90 | TOMLINS_PROSTATE_CANCER_UP | MSigDB lists | TOMLINS_PROSTATE_CANCER_UP | 38 | 13 | 17377 | 2626 |
PPIB,UAP1,PARG,BDH1,NACA,DAPK1,SND1,SOX4,SEC16A,PDLIM5,F2R,RAB11A,ATP6V1G1 |
| 2.748e-03 | -5.90 | REACTOME_GLUCOSE_TRANSPORT | MSigDB lists | REACTOME_GLUCOSE_TRANSPORT | 38 | 13 | 17377 | 2626 |
NUP188,NUP210,RAE1,SLC2A1,NUP107,NUP54,NUP62,NUP155,NUP153,NUP85,AAAS,NUP205,SEH1L |
| 2.748e-03 | -5.90 | BIOCARTA_FCER1_PATHWAY | MSigDB lists | BIOCARTA_FCER1_PATHWAY | 38 | 13 | 17377 | 2626 |
CALM2,VAV1,PPP3CA,NFATC3,SHC1,RAF1,NFATC2,PPP3CB,ELK1,LYN,MAPK1,HRAS,MAPK3 |
| 2.748e-03 | -5.90 | ELLWOOD_MYC_TARGETS_DN | MSigDB lists | ELLWOOD_MYC_TARGETS_DN | 38 | 13 | 17377 | 2626 |
DNAJC10,CHMP2A,CDS2,IDE,UFC1,TMEM97,EZR,TMED3,FKBP2,MCFD2,DAZAP2,PTTG1IP,PDIA6 |
| 2.750e-03 | -5.90 | response to peptide | biological process | GO:1901652 | 459 | 92 | 17256 | 2622 |
MAX,SLC2A1,WDTC1,ATP6V1B2,PRKACA,MAPK14,LYN,GNB2,APP,PRNP,EEF2K,CDK5,USF1,ATP6V0B,PDK2,RAB8A,CCNA2,MDM2,SHC1,GOT2,ADCY9,PIK3R2,SRSF4,AKR1B1,UPRT,CDKN1B,AHCYL1,CDC5L,ADCY7,ATP6V1G1,KLF10,AKT2,KAT7,BTG2,GNG7,ATP6V0A1,CDC6,LRP5,ERBIN,SOCS7,HHEX,IDE,SCAP,OGT,STAT1,ATP6V0C,MAPK1,C2CD5,ATP6V0E1,SLC25A33,AGTRAP,SRSF6,PSEN1,AP3S1,FOXO3,ARID1B,CFLAR,PTPN2,PTEN,ARHGEF2,ATP6V0A2,TIMELESS,CYC1,CREB1,STAT3,ATP6V0D1,MYO5A,TGFB1,PDPK1,CYFIP1,TNFAIP3,PRKDC,DENND4C,PRKAR1B,RANGAP1,SRSF5,ADRB2,MEN1,PKM,PDE3B,APPL1,IRF5,MAPK3,CAT,EPRS,TSC1,CACNB1,ATP6V1D,CSK,ATP6V1C1,RBBP4,CPEB2 |
| 2.753e-03 | -5.89 | GO_I_SMAD_BINDING | MSigDB lists | GO_I_SMAD_BINDING | 11 | 6 | 17377 | 2626 |
SMAD2,SMAD1,SMURF1,SMAD4,AXIN1,AXIN2 |
| 2.753e-03 | -5.89 | GO_REGULATION_OF_GOLGI_ORGANIZATION | MSigDB lists | GO_REGULATION_OF_GOLGI_ORGANIZATION | 11 | 6 | 17377 | 2626 |
MAPK1,MAP2K2,STX18,MYO5A,MAPK3,DNM2 |
| 2.753e-03 | -5.89 | GO_CYTOSOLIC_PROTEASOME_COMPLEX | MSigDB lists | GO_CYTOSOLIC_PROTEASOME_COMPLEX | 11 | 6 | 17377 | 2626 |
UBQLN4,PSMD2,PSMD1,IDE,PSMC1,PSMC4 |
| 2.753e-03 | -5.89 | BIOCARTA_CDK5_PATHWAY | MSigDB lists | BIOCARTA_CDK5_PATHWAY | 11 | 6 | 17377 | 2626 |
CDK5,MAPK1,HRAS,RAF1,MAP2K2,MAPK3 |
| 2.753e-03 | -5.89 | GO_GOLGI_RIBBON_FORMATION | MSigDB lists | GO_GOLGI_RIBBON_FORMATION | 11 | 6 | 17377 | 2626 |
GCC2,GOLGA2,STX16,MYO18A,OPTN,VTI1A |
| 2.753e-03 | -5.89 | BIOCARTA_P35ALZHEIMERS_PATHWAY | MSigDB lists | BIOCARTA_P35ALZHEIMERS_PATHWAY | 11 | 6 | 17377 | 2626 |
CDK5,PPP2CA,CSNK1A1,APP,CAPN1,CSNK1D |
| 2.753e-03 | -5.89 | GO_POSITIVE_REGULATION_OF_INTRACELLULAR_STEROID_HORMONE_RECEPTOR_SIGNALING_PATHWAY | MSigDB lists | GO_POSITIVE_REGULATION_OF_INTRACELLULAR_STEROID_HORMONE_RECEPTOR_SIGNALING_PATHWAY | 11 | 6 | 17377 | 2626 |
DDX5,PPP5C,PARK7,NCOA2,BUD31,DDX17 |
| 2.753e-03 | -5.89 | GO_CELL_TRAILING_EDGE | MSigDB lists | GO_CELL_TRAILING_EDGE | 11 | 6 | 17377 | 2626 |
EZR,MYH9,ICAM2,SELPLG,PIP5K1C,FLOT1 |
| 2.753e-03 | -5.89 | GO_ESCRT_III_COMPLEX | MSigDB lists | GO_ESCRT_III_COMPLEX | 11 | 6 | 17377 | 2626 |
CHMP2A,CHMP4B,VPS4A,CHMP4A,CHMP2B,CHMP7 |
| 2.753e-03 | -5.89 | GO_ALTERNATIVE_MRNA_SPLICING_VIA_SPLICEOSOME | MSigDB lists | GO_ALTERNATIVE_MRNA_SPLICING_VIA_SPLICEOSOME | 11 | 6 | 17377 | 2626 |
RBM17,CDK13,SRSF6,HNRNPM,SRSF1,PQBP1 |
| 2.753e-03 | -5.89 | REACTOME_CDC6_ASSOCIATION_WITH_THE_ORC_ORIGIN_COMPLEX | MSigDB lists | REACTOME_CDC6_ASSOCIATION_WITH_THE_ORC_ORIGIN_COMPLEX | 11 | 6 | 17377 | 2626 |
CDC6,ORC1,ORC3,E2F2,E2F1,E2F3 |
| 2.753e-03 | -5.89 | GO_PROTON_TRANSPORTING_TWO_SECTOR_ATPASE_COMPLEX_PROTON_TRANSPORTING_DOMAIN | MSigDB lists | GO_PROTON_TRANSPORTING_TWO_SECTOR_ATPASE_COMPLEX_PROTON_TRANSPORTING_DOMAIN | 11 | 6 | 17377 | 2626 |
ATP6V0A1,ATP6V0A2,ATP6V0C,ATP6V0B,ATP6V0D1,ATP6V0E1 |
| 2.759e-03 | -5.89 | RBM4B (RNA binding motif protein 4B) | protein interactions | 83759 | 61 | 19 | 17029 | 2761 |
RPP25,STAU1,ZCCHC8,SUZ12,CUL3,RPL15,BRIX1,MYEF2,RBM4,MATR3,APP,ZFR,NIP7,UTP18,RRS1,UTP4,FTSJ3,HNRNPM,CDC5L |
| 2.759e-03 | -5.89 | ZFP36 (ZFP36 ring finger protein) | protein interactions | 7538 | 61 | 19 | 17029 | 2761 |
EXOSC6,DNAJB1,COMMD6,APP,TFRC,EDC3,PPP2CA,MAP3K4,HNRNPA2B1,HSPA4,HDAC7,TANK,DCP1A,UPF2,CNOT6,CNOT6L,METTL9,YWHAH,PABPC1 |
| 2.759e-03 | -5.89 | CTNNBL1 (catenin beta like 1) | protein interactions | 56259 | 61 | 19 | 17029 | 2761 |
ZCCHC10,EWSR1,PRPF3,LUC7L,SF3A2,KPNA1,HSPA4,CTNNBL1,NSRP1,PPP1R8,U2SURP,PRDM4,CDCA7L,BUD31,STAT1,KPNA2,SRPK2,CDC5L,PRPF19 |
| 2.765e-03 | -5.89 | SMARCB1 (SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1) | protein interactions | 6598 | 175 | 43 | 17029 | 2761 |
MIF4GD,FAM208B,ARID2,MECP2,GADD45G,SMARCA4,TOP2B,MAP1LC3B,QSOX2,ARID1B,APP,TFAP4,RB1,EIF4A3,MCPH1,SMARCE1,CARM1,HNRNPM,PDPK1,UBQLN4,PHF10,RB1CC1,VHL,CUL3,LNX2,BRCA1,PBRM1,ARID1A,CDC23,KMT2C,POLR2A,CAND1,MBIP,CHMP4A,C1orf131,GOLGA2,BCL7C,KMT2B,ATP5F1A,RBBP4,TAF6,HDAC2,SMARCD1 |
| 2.765e-03 | -5.89 | EMD (emerin) | protein interactions | 2010 | 175 | 43 | 17029 | 2761 |
BCCIP,COX15,EWSR1,SUZ12,RAF1,DHX9,MYH9,SIKE1,GMCL1,SEC16A,TUBGCP2,FANCI,LMNA,SAP130,VAV1,BANF1,CDC37,SPTAN1,YTHDC1,SNRNP200,PRKDC,TMEM216,SMU1,CUL3,LSM8,RCOR1,NFATC2,BCLAF1,VDAC1,MCM2,TRIM28,EVC2,RBL1,MAPK6,AEN,MBOAT1,ACTB,ZRANB2,COPS6,CLN3,TUBB,BYSL,PDCD4 |
| 2.771e-03 | -5.89 | teratoma | COSMIC cancer mutations | teratoma | 52 | 16 | 17385 | 2587 |
EWSR1,DNMT3A,NRAS,INTS7,NF1,PTEN,VHL,SF3B1,AXIN1,MSH2,DHX9,SMARCA4,KRAS,HRAS,SMAD4,CDKN2A |
| 2.780e-03 | -5.89 | Ldh_1_C | pfam domains | PF02866 | 8 | 5 | 17054 | 2545 |
MDH1,UEVLD,MDH2,LDHA,LDHB |
| 2.780e-03 | -5.89 | MIT | pfam domains | PF04212 | 8 | 5 | 17054 | 2545 |
ULK3,VPS4A,RPS6KC1,SNX15,CAPN7 |
| 2.780e-03 | -5.89 | Ldh_1_N | pfam domains | PF00056 | 8 | 5 | 17054 | 2545 |
MDH1,UEVLD,MDH2,LDHA,LDHB |
| 2.780e-03 | -5.89 | PAM2 | pfam domains | PF07145 | 8 | 5 | 17054 | 2545 |
USP10,PAIP1,GSPT2,ATXN2L,PAIP2 |
| 2.785e-03 | -5.88 | breast-carcinoma-basal_(triple-negative)_carcinoma | COSMIC cancer mutations | breast-carcinoma-basal_(triple-negative)_carcinoma | 3035 | 502 | 17385 | 2587 |
CCDC93,FGFR1OP,ZBTB10,MAX,TSC2,LUZP1,PRKCSH,ZDHHC8,XIAP,USP39,MYEF2,FBXO22,EEF2K,ANKRD26,ASAP2,RABGAP1L,FIZ1,NUP153,CDC25B,TFG,TIPARP,DNMT1,SENP1,USP34,SRP72,BAK1,ORAI2,ERCC1,NRAS,GABPA,AKT2,MKI67,SMC2,DIDO1,USP22,AURKB,CCNF,CBFB,GINS4,TRIM47,AHNAK,WAS,SMAD2,RBM47,RAD18,AXIN1,TPP2,ITGB1,OGT,RNASEL,CHPF2,TRAF5,ARRB2,ZNF598,HDAC2,PDCD4,DDX42,HIVEP3,HSPH1,EWSR1,RHOC,PRKAA1,VAV2,RRM1,RAB23,ACAP1,MAN2B1,EIF2AK4,NOTCH2,APH1B,PSEN1,CDC73,MCTS1,RAVER2,SMC3,MEX3C,ZNRF2,INTS7,ATIC,PHF14,MSH2,DAPK1,RNF135,ANKHD1,EEF1D,SOCS5,GCC2,ZNF84,PRRC2A,RDH10,MFNG,USP10,UHRF1BP1,RIT1,PLEC,ARID1A,MTX1,ADRB2,ELK1,RHOB,NCDN,FAS,HMGN2,XRCC5,PTPRF,ETS2,DUSP3,ZFP92,ERGIC3,ACLY,PIAS2,USP32,VCPIP1,SAMD8,GPI,NDE1,MAP3K5,CDK2,HEXA,CABLES1,CDKN2A,ABCA3,ATXN3,DNMT3A,TRIP10,RAF1,SUZ12,ANK3,RAC1,MON1B,VTI1A,MYH9,NIT2,BCL2L1,ZNF267,SLC25A44,PRKACA,STMN1,KTN1,REPS1,ANKIB1,CCNA2,FBXL6,SHC1,KDM2A,RALB,UCHL5,LPIN2,ZCCHC2,ADCY9,SOCS6,NSFL1C,NUP107,CDKN1B,TTC3,RNF19A,RNASEH2A,AQR,MAVS,RBM15,ATF2,ZC3H3,CDK12,CFL1,DCTN1,ANKLE2,SHOC2,BRD4,ERF,FAM118B,ELP4,PKMYT1,MEF2D,GSTCD,TANC1,ERC1,EML4,TRIM28,TAF2,PPP2CA,RAD51C,JAK1,PPP2R5A,SAFB,CAMKMT,STAT1,SEL1L,TICAM1,FUS,PITRM1,GEN1,EYA2,POLQ,RHEBL1,PRPF4B,USP13,OTUD5,ZNF786,NCOR2,B4GALT5,MECP2,SESTD1,TCF3,BRAP,BLM,IL21R,ETS1,FOXO3,HEATR5B,MAD2L2,NEIL2,TMCC3,WWP2,RFWD3,CAPN2,RBM17,PDCD10,GATC,HUWE1,PTEN,PPP1R8,PRDM4,AXIN2,PTPN11,LTN1,SLC38A10,UBE3B,CREB1,FBXL19,MTX2,NCOA2,MSH6,PDPK1,ZFP64,TNFAIP3,KAT2A,NET1,PARP4,ILF3,ADSL,MTMR12,OTUD3,MACF1,KLF6,TSR2,MARK2,PICALM,FADD,ZNF862,ZNF180,FBXO21,KEAP1,CCDC6,ZHX1,WNT5B,MFAP1,MAPK6,TFDP1,PML,LRPPRC,PPP1R11,RGL1,PARP10,BRWD3,TAF6,YWHAH,FAF1,DDB1,GPATCH4,ZNF76,SKA3,NF1,DCAF15,GPBP1L1,TRIM11,PPP1R15B,CSNK2A1,ZNF107,S1PR2,USP48,UBQLN2,MAPK14,BIRC2,LIN9,FANCL,DLG5,ABL2,DST,NUP210,RAP1A,CDC42,GOT2,ZNF639,JAZF1,RCSD1,PIK3R2,SLC44A1,XRCC2,ETV6,GPATCH1,JOSD1,TCEA1,MYBL1,OGG1,CDC37,VPS13B,PLK1,SEPT9,CELSR2,MIOS,NCK1,APH1A,VHL,RAD51AP1,LRBA,RRM2,CDC6,LRP5,ARHGDIB,BRCA1,ESYT1,KMT2C,ANLN,USP21,RHEB,DPYSL3,MAN2A2,FBXO28,E2F4,SOCS4,ADAM9,STK11,DVL1,CHEK2,COPS6,SASS6,POT1,NUMB,PARP12,HJURP,CENPF,LAMTOR3,PCSK7,CTCF,MEF2A,THRAP3,DOCK11,RAPGEF6,TNS3,RB1,ZNF449,VMP1,MBD2,XPA,ARL6IP1,ZNF335,CTR9,AHDC1,BCL2,KNTC1,MAML1,UBE3C,ZRANB1,CIC,SUGP2,OXR1,KRAS,EIF4G2,MASTL,GNAS,SDHB,TSC1,MBIP,GOLGA4,PCM1,RBM25,UAP1,PALB2,ZFP90,YWHAZ,NUP62,MYO9A,RBBP4,TOB1,PDSS2,MBD1,TCF12,WASF2,USP7,PRKAB1,ASH1L,CYLD,CORO7,TRAF7,MPHOSPH8,ARID2,FOXM1,SLC2A1,PMS2,ZFYVE21,SMARCA4,PLAGL2,IRF3,EXT2,ZNF121,RPAIN,USP5,VAV1,CSDE1,ATP6V0B,MDM2,DUS4L,NVL,AKAP8,EXOSC1,CS,RPN2,ABI1,DVL2,POU2AF1,SLC39A9,ARHGAP17,BIRC3,RNF25,SLC26A6,METTL2A,NFATC2,OGDH,KDM1B,FANCE,EIF3H,USP36,PON2,DNAJC10,TAB2,ZNF700,STK38,STAT6,UHRF2,NCOA1,USP11,AKNA,H3F3A,SMURF1,BRD9,MAPK1,ABCA1,USP53,SMAD4,PDCD2L,PARD3,ATXN7L2,SMAP1,TRIP12,CASP6,EYA1,CHIC2,KLF13,NKRF,CSNK1A1,FZD6,FBXO5,HERC3,FGFR3,IRF4,MZT2A,CTNNBL1,CWC27,PPIG,BRD7,DDX31,SS18L1,POLR1B,STAT3,MYO5A,TGFB1,YTHDC1,ADAM17,RHOA,HMGN1,ASPM,MIER1,ARHGEF12,MEN1,PRMT2,PCGF1,TFEB,MAPK3,FBXO41,ATP6V1D,BIRC5,ELMO1,TFE3,NEIL3,OSBPL8,DTX4,USP20,ZRANB2,RBPJ,ACADM,CENPT,HRAS |
| 2.785e-03 | -5.88 | basal_(triple-negative)_carcinoma | COSMIC cancer mutations | basal_(triple-negative)_carcinoma | 3035 | 502 | 17385 | 2587 |
CCDC93,FGFR1OP,ZBTB10,MAX,TSC2,LUZP1,PRKCSH,ZDHHC8,XIAP,USP39,MYEF2,FBXO22,EEF2K,ANKRD26,ASAP2,RABGAP1L,FIZ1,NUP153,CDC25B,TFG,TIPARP,DNMT1,SENP1,USP34,SRP72,BAK1,ORAI2,ERCC1,NRAS,GABPA,AKT2,MKI67,SMC2,DIDO1,USP22,AURKB,CCNF,CBFB,GINS4,TRIM47,AHNAK,WAS,SMAD2,RBM47,RAD18,AXIN1,TPP2,ITGB1,OGT,RNASEL,CHPF2,TRAF5,ARRB2,ZNF598,HDAC2,PDCD4,DDX42,HIVEP3,HSPH1,EWSR1,RHOC,PRKAA1,VAV2,RRM1,RAB23,ACAP1,MAN2B1,EIF2AK4,NOTCH2,APH1B,PSEN1,CDC73,MCTS1,RAVER2,SMC3,MEX3C,ZNRF2,INTS7,ATIC,PHF14,MSH2,DAPK1,RNF135,ANKHD1,EEF1D,SOCS5,GCC2,ZNF84,PRRC2A,RDH10,MFNG,USP10,UHRF1BP1,RIT1,PLEC,ARID1A,MTX1,ADRB2,ELK1,RHOB,NCDN,FAS,HMGN2,XRCC5,PTPRF,ETS2,DUSP3,ZFP92,ERGIC3,ACLY,PIAS2,USP32,VCPIP1,SAMD8,GPI,NDE1,MAP3K5,CDK2,HEXA,CABLES1,CDKN2A,ABCA3,ATXN3,DNMT3A,TRIP10,RAF1,SUZ12,ANK3,RAC1,MON1B,VTI1A,MYH9,NIT2,BCL2L1,ZNF267,SLC25A44,PRKACA,STMN1,KTN1,REPS1,ANKIB1,CCNA2,FBXL6,SHC1,KDM2A,RALB,UCHL5,LPIN2,ZCCHC2,ADCY9,SOCS6,NSFL1C,NUP107,CDKN1B,TTC3,RNF19A,RNASEH2A,AQR,MAVS,RBM15,ATF2,ZC3H3,CDK12,CFL1,DCTN1,ANKLE2,SHOC2,BRD4,ERF,FAM118B,ELP4,PKMYT1,MEF2D,GSTCD,TANC1,ERC1,EML4,TRIM28,TAF2,PPP2CA,RAD51C,JAK1,PPP2R5A,SAFB,CAMKMT,STAT1,SEL1L,TICAM1,FUS,PITRM1,GEN1,EYA2,POLQ,RHEBL1,PRPF4B,USP13,OTUD5,ZNF786,NCOR2,B4GALT5,MECP2,SESTD1,TCF3,BRAP,BLM,IL21R,ETS1,FOXO3,HEATR5B,MAD2L2,NEIL2,TMCC3,WWP2,RFWD3,CAPN2,RBM17,PDCD10,GATC,HUWE1,PTEN,PPP1R8,PRDM4,AXIN2,PTPN11,LTN1,SLC38A10,UBE3B,CREB1,FBXL19,MTX2,NCOA2,MSH6,PDPK1,ZFP64,TNFAIP3,KAT2A,NET1,PARP4,ILF3,ADSL,MTMR12,OTUD3,MACF1,KLF6,TSR2,MARK2,PICALM,FADD,ZNF862,ZNF180,FBXO21,KEAP1,CCDC6,ZHX1,WNT5B,MFAP1,MAPK6,TFDP1,PML,LRPPRC,PPP1R11,RGL1,PARP10,BRWD3,TAF6,YWHAH,FAF1,DDB1,GPATCH4,ZNF76,SKA3,NF1,DCAF15,GPBP1L1,TRIM11,PPP1R15B,CSNK2A1,ZNF107,S1PR2,USP48,UBQLN2,MAPK14,BIRC2,LIN9,FANCL,DLG5,ABL2,DST,NUP210,RAP1A,CDC42,GOT2,ZNF639,JAZF1,RCSD1,PIK3R2,SLC44A1,XRCC2,ETV6,GPATCH1,JOSD1,TCEA1,MYBL1,OGG1,CDC37,VPS13B,PLK1,SEPT9,CELSR2,MIOS,NCK1,APH1A,VHL,RAD51AP1,LRBA,RRM2,CDC6,LRP5,ARHGDIB,BRCA1,ESYT1,KMT2C,ANLN,USP21,RHEB,DPYSL3,MAN2A2,FBXO28,E2F4,SOCS4,ADAM9,STK11,DVL1,CHEK2,COPS6,SASS6,POT1,NUMB,PARP12,HJURP,CENPF,LAMTOR3,PCSK7,CTCF,MEF2A,THRAP3,DOCK11,RAPGEF6,TNS3,RB1,ZNF449,VMP1,MBD2,XPA,ARL6IP1,ZNF335,CTR9,AHDC1,BCL2,KNTC1,MAML1,UBE3C,ZRANB1,CIC,SUGP2,OXR1,KRAS,EIF4G2,MASTL,GNAS,SDHB,TSC1,MBIP,GOLGA4,PCM1,RBM25,UAP1,PALB2,ZFP90,YWHAZ,NUP62,MYO9A,RBBP4,TOB1,PDSS2,MBD1,TCF12,WASF2,USP7,PRKAB1,ASH1L,CYLD,CORO7,TRAF7,MPHOSPH8,ARID2,FOXM1,SLC2A1,PMS2,ZFYVE21,SMARCA4,PLAGL2,IRF3,EXT2,ZNF121,RPAIN,USP5,VAV1,CSDE1,ATP6V0B,MDM2,DUS4L,NVL,AKAP8,EXOSC1,CS,RPN2,ABI1,DVL2,POU2AF1,SLC39A9,ARHGAP17,BIRC3,RNF25,SLC26A6,METTL2A,NFATC2,OGDH,KDM1B,FANCE,EIF3H,USP36,PON2,DNAJC10,TAB2,ZNF700,STK38,STAT6,UHRF2,NCOA1,USP11,AKNA,H3F3A,SMURF1,BRD9,MAPK1,ABCA1,USP53,SMAD4,PDCD2L,PARD3,ATXN7L2,SMAP1,TRIP12,CASP6,EYA1,CHIC2,KLF13,NKRF,CSNK1A1,FZD6,FBXO5,HERC3,FGFR3,IRF4,MZT2A,CTNNBL1,CWC27,PPIG,BRD7,DDX31,SS18L1,POLR1B,STAT3,MYO5A,TGFB1,YTHDC1,ADAM17,RHOA,HMGN1,ASPM,MIER1,ARHGEF12,MEN1,PRMT2,PCGF1,TFEB,MAPK3,FBXO41,ATP6V1D,BIRC5,ELMO1,TFE3,NEIL3,OSBPL8,DTX4,USP20,ZRANB2,RBPJ,ACADM,CENPT,HRAS |
| 2.794e-03 | -5.88 | GO_GTPASE_ACTIVITY | MSigDB lists | GO_GTPASE_ACTIVITY | 236 | 52 | 17377 | 2626 |
RHOG,RAB14,RAB11B,RAC1,GSPT2,RAB23,RRAGC,ARF1,RAB6A,RAB11A,GNB2,GFM2,GTPBP3,RAB21,RAB8A,RAP1A,CDC42,RALB,RAB35,ARF5,RAB4A,EFTUD2,DNM2,EIF5,GNAI2,RHOA,SEPT9,NOA1,RAB7A,GTPBP4,TUFM,KRAS,ARHGDIB,RIT1,RHOT1,RAB1A,RHOT2,RAB5B,GUF1,RAB22A,LSG1,RHEB,RHOB,ARF4,RAB2B,MFN2,GNAS,GNA12,RAB18,RAB24,HRAS,TUBB |
| 2.798e-03 | -5.88 | FHA | pfam domains | PF00498 | 30 | 11 | 17054 | 2545 |
AFDN,CEP170B,STARD9,AGGF1,FOXK1,KIF14,KIF13B,PPP1R8,MKI67,CHEK2,TCF19 |
| 2.804e-03 | -5.88 | V$PAX4_01 | MSigDB lists | V$PAX4_01 | 247 | 54 | 17377 | 2626 |
MAPRE1,ZCCHC9,TRERF1,PHF23,DNAJB2,GADD45G,FAM76A,KLF13,PLAGL2,USP39,CHKB,SLC35B1,MXD4,SND1,AP1B1,GNB2,POFUT1,CDC73,PABPC4,SAP130,TFAP4,ITGB8,MEGF8,ZFYVE27,MAML1,FBXL19,PABPC1,TMED2,SPTAN1,CPNE1,EIF5A,ABHD2,PHF20L1,KLF10,CIC,ACSL3,ARHGEF12,PACS1,WDR81,PICALM,NCDN,DDX17,IWS1,HMGN2,UBTF,LEMD2,ZNF777,SYNCRIP,HNRNPR,OAZ2,E2F1,YWHAZ,GALNT10,SMAD1 |
| 2.804e-03 | -5.88 | GO_ORGANOPHOSPHATE_BIOSYNTHETIC_PROCESS | MSigDB lists | GO_ORGANOPHOSPHATE_BIOSYNTHETIC_PROCESS | 410 | 83 | 17377 | 2626 |
KARS,PIGM,PPCS,SUCLG1,PIGQ,HEXB,UCK2,AGPAT1,UCK1,CHKB,SLC35B2,CDIPT,GGPS1,LCLAT1,CPNE3,FLAD1,MTMR4,DUT,PIK3R2,ADCY9,LPIN2,SLC44A1,PPCDC,UPRT,SLC26A2,GPD1L,ADCY7,CPNE1,PGAP2,DPM1,ATP6V0A1,RRM2,MTMR6,TAZ,PRPSAP1,STOML2,ABHD5,AGPAT2,MBOAT1,PDXK,CHPT1,NADSYN1,PIGN,CDS2,RRM1,TKT,AGPAT3,ARF1,PMVK,PIP4K2A,PIP5K1C,CHKA,ERH,FGFR3,NUS1,GART,PTEN,ATIC,PIGG,PTPN11,ATP6V0A2,PCYT2,PIKFYVE,LPCAT1,AMPD2,TGFB1,TK1,GUK1,PIGT,PGS1,PIP4K2C,ADSL,DCTD,PI4K2A,ADSS,MTMR3,DCK,PRPS2,LPCAT4,TBPL1,IMPDH1,SAMD8,PTDSS1 |
| 2.806e-03 | -5.88 | Glycerophospholipid Biosynthetic Pathway | WikiPathways | WP2533 | 21 | 9 | 5312 | 837 |
CDS2,PGS1,LPIN2,PCYT2,CHKB,CDIPT,CHPT1,PTDSS1,PI4K2A |
| 2.806e-03 | -5.88 | Nanomaterial induced apoptosis | WikiPathways | WP2507 | 21 | 9 | 5312 | 837 |
BAK1,CASP6,MCL1,CYCS,BCL2L1,FADD,HTRA2,CFLAR,FAS |
| 2.810e-03 | -5.87 | MATSUDA_NATURAL_KILLER_DIFFERENTIATION | MSigDB lists | MATSUDA_NATURAL_KILLER_DIFFERENTIATION | 456 | 91 | 17377 | 2626 |
ST13,HNRNPAB,NOP2,TSC22D3,XIAP,EBNA1BP2,STMN1,GNB2,MRPL19,DST,UBXN2A,AP3S2,TNPO2,KIF22,CORO1A,F2R,RHBDD2,TACC3,OAF,RNF25,MRPL12,WIPF1,RRM2,EDF1,CADM1,CDC23,SOX4,MCM2,AHNAK,TIMM13,RPS14,TULP3,ITGB1,ACTB,FBXL3,ATMIN,SSRP1,OTUD5,GALK1,COX5B,RHOC,TKT,MXD4,NCAPG,TFRC,RGS1,FZD6,MAN1A1,FKBP1A,DTL,CTNNBL1,SUV39H2,MCM5,PPIL2,BUD31,TIMELESS,TNPO3,MRPL54,MDFIC,SGCB,IFT46,MYO5A,ZNF189,LDHB,EIF5A,TK1,PRIM2,CSRP1,TSPAN31,RHOT2,KIF11,KLF6,CHCHD6,TARS,HSPA1B,PSMC4,MYO1F,PTPRF,UPF1,SYNCRIP,CDCA5,ACLY,PPP3R1,LY75,GPI,SMPD4,HEXA,GPATCH4,IPO4,ALS2,RAB3IL1 |
| 2.814e-03 | -5.87 | GSE36476_CTRL_VS_TSST_ACT_72H_MEMORY_CD4_TCELL_YOUNG_UP | MSigDB lists | GSE36476_CTRL_VS_TSST_ACT_72H_MEMORY_CD4_TCELL_YOUNG_UP | 182 | 42 | 17377 | 2626 |
UBL3,HECA,PNISR,TSC22D3,TMEM41B,TMX4,YTHDF3,DNAJB1,DAZAP2,RLF,CHD1,DNAJB9,MOAP1,ADD3,KLHL20,ZNF639,CRY2,PIK3IP1,TTC17,PLCL2,CITED2,TIPARP,USP34,PLK3,TNFAIP3,PBXIP1,TSPYL4,COQ10B,BTG2,RPL38,CIRBP,DIDO1,KLF6,TMEM127,FBXO21,MBIP,GOLGA4,PIAS2,SMURF1,LONP2,TOB1,CCDC59 |
| 2.814e-03 | -5.87 | GSE45365_NK_CELL_VS_CD11B_DC_MCMV_INFECTION_UP | MSigDB lists | GSE45365_NK_CELL_VS_CD11B_DC_MCMV_INFECTION_UP | 182 | 42 | 17377 | 2626 |
SEPHS2,PKP4,KRBA1,RAE1,MOGS,PMS2,AGFG1,PLXNA1,EPHX2,LYAR,PA2G4,EIF2S2,STRBP,ZNHIT6,ZDHHC13,GTSE1,YBX1,DDX31,TTC4,GPD1L,PACS2,CARM1,TIMM50,GINS1,JMJD4,ERCC1,RFC3,NASP,CSRP1,AATF,OTUD3,GAR1,CHCHD6,CYB5A,PSMB3,CHCHD3,TMEM41A,HIPK2,CDCA5,GAS2,NDE1,SSSCA1 |
| 2.814e-03 | -5.87 | GSE21379_WT_VS_SAP_KO_CD4_TCELL_DN | MSigDB lists | GSE21379_WT_VS_SAP_KO_CD4_TCELL_DN | 182 | 42 | 17377 | 2626 |
HIVEP3,TRIM11,PTTG1,CENPF,KIF23,PPP1R16B,TTF1,FBXO5,CDKN2C,IRF4,INPP5A,GMEB1,ARL6IP1,PDS5B,GTSE1,CDC25B,GPD1L,N4BP2,ELOF1,MOB4,POU2AF1,PLK1,RHOA,TNFAIP3,BAZ2A,PBK,KCTD20,SYVN1,RAB3IP,MEN1,NEU1,CAT,ALDH3B1,RAD51C,WDR11,DCK,ARNTL,QRSL1,KLHDC4,NDE1,BTBD10,E2F2 |
| 2.814e-03 | -5.87 | KAECH_NAIVE_VS_DAY15_EFF_CD8_TCELL_UP | MSigDB lists | KAECH_NAIVE_VS_DAY15_EFF_CD8_TCELL_UP | 182 | 42 | 17377 | 2626 |
SLC12A7,SRM,GALK1,RPS2,ADD1,DNAJB2,MCCC1,MOGS,CRLF3,METTL3,BZW2,BIRC2,PIP4K2A,PAPOLA,GSTK1,PA2G4,IL6ST,TIMELESS,ATP6V0A2,TTC3,METTL9,SMC4,ABCC5,ELOVL5,EMB,WDR1,RAB3IP,HAGH,RPSA,ZFR,ANKRD10,SH3BP5,GALNT2,ETS2,ACADM,YY1,SMAD1,EYA2,HDAC2,TUBB,IPO4,PTOV1 |
| 2.814e-03 | -5.87 | GSE5589_LPS_VS_LPS_AND_IL10_STIM_IL6_KO_MACROPHAGE_180MIN_DN | MSigDB lists | GSE5589_LPS_VS_LPS_AND_IL10_STIM_IL6_KO_MACROPHAGE_180MIN_DN | 182 | 42 | 17377 | 2626 |
MMACHC,SYS1,RWDD1,NDUFB6,TRIP12,B4GALT5,SRGN,PRKAA1,TRMT6,NIPA2,SNN,OAT,RGS1,WRNIP1,CSDE1,TMEM69,LYAR,PSMD2,UBE2Q2,ITGB8,NOL11,ATIC,TTC9C,LTN1,FBL,F2R,GPX4,NSUN2,LYRM1,SCFD2,SEPT7,DHX15,CCDC127,DAP3,SERTAD2,ZNF330,HIPK2,SRSF3,TMEM14A,LTA4H,IPO4,HDAC2 |
| 2.814e-03 | -5.87 | GSE2770_IL12_VS_IL4_TREATED_ACT_CD4_TCELL_48H_UP | MSigDB lists | GSE2770_IL12_VS_IL4_TREATED_ACT_CD4_TCELL_48H_UP | 182 | 42 | 17377 | 2626 |
H2AFZ,SYS1,CHTF18,TPX2,PXMP2,CDC42SE2,SND1,COMMD5,KIFC1,OIP5,CDKN2C,ERH,PSMD1,PSMA6,RNASEK,RAB4A,TPST1,FNIP2,SLC38A10,RNF26,CLTB,ARL5A,IMPA2,ALDH9A1,ENPP4,RAD51AP1,MRPS10,SREK1,ANLN,RAB1A,APPL1,ARF4,AKAP1,CDC16,IDE,RAD18,NSMCE2,AP1S1,XRCC3,TMEM101,E2F2,RTN3 |
| 2.814e-03 | -5.87 | GSE8921_UNSTIM_VS_TLR1_2_STIM_MONOCYTE_3H_DN | MSigDB lists | GSE8921_UNSTIM_VS_TLR1_2_STIM_MONOCYTE_3H_DN | 182 | 42 | 17377 | 2626 |
CDS2,SYS1,SUCLG1,DNAJB2,RHOC,SLC4A2,ATG2B,CCNL2,TWF2,SYNRG,ANKIB1,WWP2,PRNP,GOLM1,APLP2,RINL,MBD2,SRI,UPF2,MARCH2,JTB,PFKFB3,NFATC2,MTMR12,WDR81,AMDHD2,IL12RB1,NDRG3,ARPC1A,BBS12,CYB5A,MAPK3,RAB18,ACOX1,WNT5B,PRDX5,APPL2,ARAP1,PML,SLC25A19,PGAM1,ANAPC4 |
| 2.814e-03 | -5.87 | GSE21774_CD56_BRIGHT_VS_DIM_CD62L_POSITIVE_NK_CELL_DN | MSigDB lists | GSE21774_CD56_BRIGHT_VS_DIM_CD62L_POSITIVE_NK_CELL_DN | 182 | 42 | 17377 | 2626 |
WSB2,EXOC3,DNAJC2,GCLM,REPS2,MRI1,UROD,MRPS26,COMMD5,PABPC4,SAC3D1,GOLM1,APLP2,SLC38A5,DAD1,ATP13A3,EXOSC1,TPST1,MRPL54,RNF19A,MINPP1,TTLL12,SCYL3,HTRA2,ELL2,BTAF1,OAF,UTP15,TBRG4,SEPT8,RRM2,GAR1,GFER,USP36,NECAP2,POLR2J,E2F4,PRPF4,STK11,SLC22A23,WDR91,ZMAT3 |
| 2.816e-03 | -5.87 | NSUN2 (NOP2/Sun RNA methyltransferase family member 2) | protein interactions | 54888 | 79 | 23 | 17029 | 2761 |
TP53RK,PPP1R12A,HARS,ACTR3,PMS2,CUL3,CUL1,USP39,RANGAP1,AURKB,EFL1,METTL3,SH3GLB1,PNO1,RPA1,CAND1,PFDN5,RPS27A,ZNF746,FBL,TTLL12,ARRB2,FUBP1 |
| 2.816e-03 | -5.87 | OIP5 (Opa interacting protein 5) | protein interactions | 11339 | 79 | 23 | 17029 | 2761 |
CCDC93,MAX,RPRD1A,TRAF7,HJURP,RAF1,CUL3,CUL1,RCOR1,KRAS,NUF2,PSMD9,GIT2,HMG20A,OIP5,ABL2,EIF4ENIF1,GRIPAP1,RABGAP1L,ARNTL,NUP62,GCC1,TACC3 |
| 2.816e-03 | -5.87 | GOLGA5 (golgin A5) | protein interactions | 9950 | 79 | 23 | 17029 | 2761 |
CCDC93,MAX,RPRD1A,TMEM216,RCOR1,NUF2,BRCA1,RAB1A,PSMD9,SPPL2B,GIT2,HMG20A,NCDN,XRCC5,OIP5,CDC42,GRIPAP1,MTMR4,RABGAP1L,ARNTL,PTAR1,ZFYVE27,B4GALT3 |
| 2.816e-03 | -5.87 | TRAF3IP1 (TRAF3 interacting protein 1) | protein interactions | 26146 | 79 | 23 | 17029 | 2761 |
CCDC93,IMMT,MAPRE2,TRAK1,MYH9,SMC2,PKM,MACF1,APP,DST,CLUAP1,GOLGA4,SMC3,PCM1,CCNA2,TAB2,MAP4,AHCY,ACTB,SSNA1,TUBB,SMC4,CDC5L |
| 2.816e-03 | -5.87 | RAB11B (RAB11B, member RAS oncogene family) | protein interactions | 9230 | 79 | 23 | 17029 | 2761 |
DDX28,RBM42,PHB2,RAB7A,HNRNPUL2,RAB6A,NUTF2,ARF1,RAB1A,RAB5B,RAB11A,APP,OPTN,RPA1,SH3BP5,RPA2,RAB8A,CDC42,WDR44,DUT,H2AFX,CDK2,PGAM1 |
| 2.820e-03 | -5.87 | Lactate/malate_DH_N | interpro domains | IPR001236 | 8 | 5 | 18492 | 2768 |
MDH1,UEVLD,MDH2,LDHA,LDHB |
| 2.820e-03 | -5.87 | Lactate/malate_DH_C | interpro domains | IPR022383 | 8 | 5 | 18492 | 2768 |
MDH1,UEVLD,MDH2,LDHA,LDHB |
| 2.820e-03 | -5.87 | Ataxin-2_C | interpro domains | IPR009818 | 8 | 5 | 18492 | 2768 |
USP10,PAIP1,GSPT2,ATXN2L,PAIP2 |
| 2.820e-03 | -5.87 | L-lactate/malate_DH | interpro domains | IPR001557 | 8 | 5 | 18492 | 2768 |
MDH1,UEVLD,MDH2,LDHA,LDHB |
| 2.826e-03 | -5.87 | GO_POSITIVE_REGULATION_OF_CATALYTIC_ACTIVITY | MSigDB lists | GO_POSITIVE_REGULATION_OF_CATALYTIC_ACTIVITY | 1460 | 258 | 17377 | 2626 |
CCNC,TXN,AGRN,TSC2,NF1,DNAJC24,CUL1,AGFG1,CCNL2,CCNB1,S1PR2,UBE2I,MAPK14,ELMOD2,GIT2,PARK7,ABL2,CDK5,CALM2,RAP1A,ASAP2,PCNA,PSMD1,CDC42,RABGAP1L,PIK3R2,RAB4A,DNM2,RP2,CDC25B,TCEA1,SENP1,COPS8,PLK1,BAK1,NCK1,APH1A,AKT2,GMFB,TOPORS,ARHGDIB,CDC6,AURKB,DCUN1D5,PRKRA,RFC2,ARF4,ABHD5,MAP3K4,TBC1D17,MID1IP1,RPS27A,PSMD8,AXIN1,ITGB1,OGT,CAB39,ADAM9,STK11,CLU,PSMC1,POT1,TBC1D12,HSPH1,GMFG,PPP1R12A,CLSPN,GORASP1,CHTF18,RHOC,GADD45G,VAV2,PRKAA1,TRIO,CIB1,ACAP1,LAMTOR3,RACGAP1,CYCS,DNAJB1,DOCK11,RGS2,PSEN1,PSMD9,APH1B,RAPGEF6,APOPT1,CFLAR,TFAP4,SNX18,RINL,MSH2,DAPK1,BCL2,MDFIC,GNAI2,TERF2,PREB,CYTH1,MAPKAPK3,PSMA1,KRAS,MAP4K3,ADRB2,CYFIP2,MAP2K2,PSMB3,ARHGAP15,FAS,PSMC4,MASTL,GNAS,TSC1,FNTA,CDC27,GOLGA2,CSK,ARAP1,CTSA,MAP3K5,MYO9A,CDKN2A,ALS2,RHOG,ANKRD27,TRAF7,TRIP10,RAF1,RAC1,MAGED1,TOR1AIP1,TPX2,TBC1D13,PRKACA,LYN,APP,BCAP31,CRKL,VAV1,PSMA6,SHC1,TBC1D22A,SH3BP1,RALB,NVL,TBC1D14,PIN1,KIF14,ADCY9,CDKN1B,PDCD2,ANAPC7,CHTOP,F2R,ABI1,HTRA2,GM2A,DVL2,ADCY7,CCT2,ARHGAP17,RFC3,TIMP2,PSRC1,PSMA8,PSMB7,DNAJC9,TOR1AIP2,CDC23,RAB1A,PSMB9,PPP2CA,DNAJC10,CDC16,JAK1,TAB2,PLEKHG4B,PSMD3,CORO1C,GADD45B,RPLP1,SCARB1,PITRM1,XRCC4,MAPK1,LRP8,MIF,GCLM,DNAJC2,PKP4,SMAP1,RPS2,SH2D3A,DEPDC1,DAP,ZFP91,DBF4,PAWR,ARF1,MYO9B,DCUN1D4,RGS1,FBXO5,GTF2F1,CCNK,PSMD2,FGFR3,PDCD10,PTEN,AHSA1,ARHGEF1,PTPN11,AXIN2,DCP1A,ARHGEF2,MAP3K14,STAT3,CAMK2G,MSH6,SPTAN1,PDPK1,TGFB1,TELO2,ADAM17,RHOA,DENND1B,NET1,DENND4C,NEK7,PRKAR1B,JTB,RABIF,ANAPC2,ARHGEF12,RANGAP1,RAB3IP,ZP3,MARK2,PICALM,FADD,SMAP2,MAPK3,PDCD6,PLAA,ELMO1,OSBPL8,PML,PKD2,HMGB2,RGL1,PSAP,UBE2C,ARHGAP23,CD81,HRAS,ANAPC4,IFI16,RAB3IL1 |
| 2.830e-03 | -5.87 | cytoskeleton-dependent intracellular transport | biological process | GO:0030705 | 160 | 38 | 17256 | 2622 |
KIF3B,DYNLL1,TRAK1,AP3M2,KIF23,RAB6A,AP3S1,IFT27,APP,COPG2,DST,KIF5B,CLUAP1,RAB21,CDC42,AP3S2,KIF13B,KIF14,KIFAP3,IFT46,MYO5A,TERF2,DCTN1,BICD2,FXR1,RHOT1,RAB1A,RHOT2,BBS12,TMEM201,PCM1,HSPB11,LRPPRC,SSNA1,CLN3,NDE1,TUBB,SNAPIN |
| 2.833e-03 | -5.87 | EHD1 (EH domain containing 1) | protein interactions | 10938 | 70 | 21 | 17029 | 2761 |
PGGT1B,PRKDC,EPN1,CCNL2,PRKRA,API5,RAB11A,KTN1,FADD,FAS,C19orf54,RAB8A,PDCD10,SNAP29,STAT6,NAXE,ATE1,TECR,EHD4,TMX1,CDC5L |
| 2.833e-03 | -5.87 | SLC39A12 (solute carrier family 39 member 12) | protein interactions | 221074 | 70 | 21 | 17029 | 2761 |
NAT14,NRAS,TMEM39A,MBLAC2,LETMD1,ABCB10,SLC29A1,ADPGK,MTX1,SLC35B2,WRB,ABHD14A,GOLM1,LEMD2,AGPAT2,SLC25A51,MICU2,ABCD1,MAVS,APOOL,MGAT5 |
| 2.833e-03 | -5.87 | RSL1D1 (ribosomal L1 domain containing 1) | protein interactions | 26156 | 70 | 21 | 17029 | 2761 |
NIFK,NOP2,SUZ12,CUL3,DHX8,CUL1,CSNK2A1,BRCA1,VDAC1,RBM4,APP,LMNA,CAND1,MDM2,RPL19,RRS1,FBL,ZC3H3,SRPK2,DDX52,HP1BP3 |
| 2.833e-03 | -5.87 | NMI (N-myc and STAT interactor) | protein interactions | 9111 | 70 | 21 | 17029 | 2761 |
TRIP12,OXR1,PSMA1,MTMR6,BRCA1,UBE2I,TOLLIP,NECAP2,BRMS1,CYHR1,HGS,STAT6,STAT1,TXLNA,COPS7B,TRAF5,SINHCAF,STAT3,MCPH1,CDKN2A,GCSH |
| 2.833e-03 | -5.87 | LYAR (Ly1 antibody reactive) | protein interactions | 55646 | 70 | 21 | 17029 | 2761 |
PHF20L1,DHX9,CUL3,GTPBP4,CUL1,EBNA1BP2,PRKRA,BRIX1,TWF2,RPS9,DHX57,PHF6,RPL23A,CAND1,RFWD3,KPNA1,ZHX1,ZNF746,TERF1,IFI16,TERF2 |
| 2.834e-03 | -5.87 | positive regulation of autophagosome assembly | biological process | GO:2000786 | 11 | 6 | 17256 | 2622 |
LRSAM1,BECN1,RALB,PIP4K2A,SH3GLB1,PIP4K2C |
| 2.834e-03 | -5.87 | nuclear pore complex assembly | biological process | GO:0051292 | 11 | 6 | 17256 | 2622 |
NUP153,NDC1,AHCTF1,NUP205,NUP107,TMEM33 |
| 2.834e-03 | -5.87 | Golgi ribbon formation | biological process | GO:0090161 | 11 | 6 | 17256 | 2622 |
GCC2,GOLGA2,STX16,MYO18A,OPTN,VTI1A |
| 2.838e-03 | -5.86 | GO_CENTRIOLE_ASSEMBLY | MSigDB lists | GO_CENTRIOLE_ASSEMBLY | 18 | 8 | 17377 | 2626 |
CCP110,CENPJ,E2F4,CNTROB,CEP63,WDR62,CDK2,SASS6 |
| 2.838e-03 | -5.86 | CHOI_ATL_CHRONIC_VS_ACUTE_DN | MSigDB lists | CHOI_ATL_CHRONIC_VS_ACUTE_DN | 18 | 8 | 17377 | 2626 |
MAT2B,MDH1,GTF3A,IARS,LRRC8D,CMTM6,CTDSP2,CGGBP1 |
| 2.838e-03 | -5.86 | REACTOME_N_GLYCAN_ANTENNAE_ELONGATION_IN_THE_MEDIAL_TRANS_GOLGI | MSigDB lists | REACTOME_N_GLYCAN_ANTENNAE_ELONGATION_IN_THE_MEDIAL_TRANS_GOLGI | 18 | 8 | 17377 | 2626 |
B4GALT5,FUT8,B4GALT1,ST8SIA2,B4GALT4,B4GALT3,MGAT5,B4GALT2 |
| 2.838e-03 | -5.86 | BIOCARTA_MEF2D_PATHWAY | MSigDB lists | BIOCARTA_MEF2D_PATHWAY | 18 | 8 | 17377 | 2626 |
CALM2,CAPN2,PPP3CA,NFATC2,CABIN1,MEF2D,PPP3CB,HDAC2 |
| 2.838e-03 | -5.86 | GO_PROTEIN_EXIT_FROM_ENDOPLASMIC_RETICULUM | MSigDB lists | GO_PROTEIN_EXIT_FROM_ENDOPLASMIC_RETICULUM | 18 | 8 | 17377 | 2626 |
DERL1,SEC61B,SURF4,SEL1L,SYVN1,LMAN1,NPLOC4,RHBDD1 |
| 2.838e-03 | -5.86 | REACTOME_MICRORNA_MIRNA_BIOGENESIS | MSigDB lists | REACTOME_MICRORNA_MIRNA_BIOGENESIS | 18 | 8 | 17377 | 2626 |
POLR2I,POLR2G,POLR2L,POLR2J,DGCR8,POLR2K,POLR2D,POLR2A |
| 2.838e-03 | -5.86 | BIOCARTA_MCM_PATHWAY | MSigDB lists | BIOCARTA_MCM_PATHWAY | 18 | 8 | 17377 | 2626 |
CDKN1B,CDC6,ORC1,ORC3,MCM2,CDK2,MCM5,CDT1 |
| 2.838e-03 | -5.86 | NAGY_TFTC_COMPONENTS_HUMAN | MSigDB lists | NAGY_TFTC_COMPONENTS_HUMAN | 18 | 8 | 17377 | 2626 |
TAF2,SAP130,KAT2A,TAF5L,TAF12,TAF6L,SUPT7L,TAF6 |
| 2.845e-03 | -5.86 | FKBP3 (FK506 binding protein 3) | protein interactions | 2287 | 44 | 15 | 17029 | 2761 |
HNRNPA2B1,MDM2,EWSR1,SYNCRIP,MTA2,DYNLL1,TIMELESS,CSNK2A1,YBX1,YY1,SEC16A,SMURF1,ABCF1,HDAC2,CGGBP1 |
| 2.845e-03 | -5.86 | ANAPC15 (anaphase promoting complex subunit 15) | protein interactions | 25906 | 44 | 15 | 17029 | 2761 |
CDC16,CDC27,PRDX5,RRM2,ANAPC2,ANAPC7,ECD,CDC23,MRPL11,PACS2,ANAPC4,CDKN2A,PRDX1,RTKN,FBXO5 |
| 2.845e-03 | -5.86 | LRRC59 (leucine rich repeat containing 59) | protein interactions | 55379 | 44 | 15 | 17029 | 2761 |
STAU1,C1orf131,EWSR1,ILF3,TMEM216,USP20,CSNK2A1,BRCA1,WDR76,MCM2,MPG,APP,LMNA,HNRNPM,CAND1 |
| 2.845e-03 | -5.86 | ERCC8 (ERCC excision repair 8, CSA ubiquitin ligase complex subunit) | protein interactions | 1161 | 44 | 15 | 17029 | 2761 |
COPS8,HMGN1,MDM2,PCNA,RBX1,PFDN4,XAB2,DDA1,RUVBL2,COPS6,PCGF1,GTF2H2,OGG1,DDB1,POLR2A |
| 2.853e-03 | -5.86 | GOLGA2 (golgin A2) | protein interactions | 2801 | 330 | 73 | 17029 | 2761 |
CCNC,FAM207A,WDYHV1,TPX2,ORC1,UBE2I,SEC16A,TCF19,PPP1R16B,RCOR3,MYEF2,PIN1,PIK3R2,TTC9C,TXLNA,CORO1A,SMARCE1,GCC1,CCAR1,ATP6V1G1,CDC5L,USO1,PPP1R18,SNRPB,DCLRE1C,RAB1A,MBD3,EIF3G,RAB2B,PPP2CA,CHCHD3,FBXO28,RBL1,SPATA2,C1orf109,PQBP1,NXT2,MCM10,PKP4,GORASP1,PRKAA1,ARID5A,CHCHD2,SECISBP2,RAB6A,IFT27,CDC73,RBM17,TFAP4,PTPN11,GTSE1,UBE3C,MVP,RNF135,TMED2,YTHDC1,STAU1,MTFR2,PSMA1,C1orf35,GORASP2,FAM50B,PATL1,ATP6V1D,FAM110A,GPS2,MFAP1,YJU2,PIAS2,PKD2,NDE1,CDK2,BYSL |
| 2.860e-03 | -5.86 | GO_NEGATIVE_REGULATION_OF_NUCLEOCYTOPLASMIC_TRANSPORT | MSigDB lists | GO_NEGATIVE_REGULATION_OF_NUCLEOCYTOPLASMIC_TRANSPORT | 70 | 20 | 17377 | 2626 |
CYLD,TXN,NF1,RAB23,RANGAP1,SOX4,PARK7,AKAP1,CDK5,KEAP1,SP100,TONSL,SRI,AXIN2,FAM89B,PKD2,NUP153,MDFIC,PARP10,FAF1 |
| 2.863e-03 | -5.86 | CEP55 (centrosomal protein 55) | protein interactions | 55165 | 107 | 29 | 17029 | 2761 |
PLK1,PDCD6IP,EWSR1,TSC22D3,SNRPB,MUM1,KIF23,WDR5,PEF1,PPP1R16B,RCOR3,RBM17,HGS,PCM1,SYNCRIP,MTMR4,CCDC6,CCDC14,MFAP1,CENPJ,PIN1,ODF2,C1orf109,CEP55,MIA2,CEP63,TFG,MAPK1,ANXA11 |
| 2.872e-03 | -5.85 | transcription elongation factor complex | cellular component | GO:0008023 | 57 | 17 | 18223 | 2701 |
ELL2,ELOA,ELP4,CDK13,RTF1,EAF2,CDC73,SUPT16H,PAF1,RB1,EPOP,TONSL,CTR9,ICE2,AFF1,CDK12,ELOF1 |
| 2.876e-03 | -5.85 | RBPJ (recombination signal binding protein for immunoglobulin kappa J region) | protein interactions | 3516 | 131 | 34 | 17029 | 2761 |
MBD1,USP7,NCOR2,RECQL,ZBTB10,MECP2,TPX2,CUL1,SMARCA4,KIF2C,NOTCH2,SND1,APP,CREM,RPA2,TFAP4,KDM2A,MBD2,H2AFY,MAML1,CGGBP1,CLPTM1,DDX24,KAT2A,CAMSAP1,RANGAP1,CDC27,L3MBTL3,NSMF,OGT,ZNF268,ZMIZ1,NR2F2,HDAC2 |
| 2.877e-03 | -5.85 | Bloom's syndrome complex | KEGG pathways | M00414 | 5 | 4 | 7161 | 1149 |
BLM,RMI1,RMI2,TOP3A |
| 2.877e-03 | -5.85 | Bloom's syndrome complex | KEGG pathways | hsa_M00414 | 5 | 4 | 7161 | 1149 |
BLM,RMI1,RMI2,TOP3A |
| 2.877e-03 | -5.85 | Glycosphingolipid biosynthesis, neolacto-series, LacCer => nLc4Cer | KEGG pathways | M00071 | 5 | 4 | 7161 | 1149 |
B4GALT1,B4GALT3,B4GALT4,B4GALT2 |
| 2.877e-03 | -5.85 | Glycosphingolipid biosynthesis, neolacto-series, LacCer => nLc4Cer | KEGG pathways | hsa_M00071 | 5 | 4 | 7161 | 1149 |
B4GALT1,B4GALT3,B4GALT4,B4GALT2 |
| 2.879e-03 | -5.85 | organelle outer membrane | cellular component | GO:0031968 | 202 | 45 | 18223 | 2701 |
TOMM20,MTX3,PHB2,RAF1,TMEM109,STARD7,LETMD1,BCL2L1,SNN,SLC25A44,PSEN1,FOXO3,MIEF1,MOAP1,TIGAR,SLC44A1,HADHB,BCL2,CISD2,MAVS,ATF2,MTX2,TRIM14,ACSL5,BAK1,SIGMAR1,ACSL3,VDAC2,MCL1,MTX1,NUTF2,RHOT1,VDAC1,TOMM40,RHOT2,SH3GLB1,CYB5A,MFN2,AKAP1,ANKZF1,ATP5MC3,RPS27A,TOMM6,LRPPRC,NIPSNAP2 |
| 2.885e-03 | -5.85 | MARK1 (microtubule affinity regulating kinase 1) | protein interactions | 4139 | 17 | 8 | 17029 | 2761 |
PRKAA1,MAP4,TAOK1,YWHAZ,STK11,YWHAH,USP21,MARK2 |
| 2.885e-03 | -5.85 | FAM122A (family with sequence similarity 122A) | protein interactions | 116224 | 17 | 8 | 17029 | 2761 |
TERF2IP,PPP2CA,PPP3CA,KLHL15,PPP3R1,KIF11,APP,PPP2R2D |
| 2.885e-03 | -5.85 | CCDC84 (coiled-coil domain containing 84) | protein interactions | 338657 | 17 | 8 | 17029 | 2761 |
GINS1,PRPF4,YWHAZ,PRPF3,SNRPG,DCAF5,RNPS1,HNRNPF |
| 2.885e-03 | -5.85 | IMPACT (impact RWD domain protein) | protein interactions | 55364 | 17 | 8 | 17029 | 2761 |
CRKL,ETS2,SMURF1,CDC73,QSOX2,REEP5,FANCI,CBX4 |
| 2.885e-03 | -5.85 | ORF24 (ORF24) | protein interactions | 4961485 | 17 | 8 | 17029 | 2761 |
RPAP3,POLR2I,POLR2G,POLR2L,POLR2J,POLR2K,POLR2A,POLR2D |
| 2.885e-03 | -5.85 | KCNA10 (potassium voltage-gated channel subfamily A member 10) | protein interactions | 3744 | 17 | 8 | 17029 | 2761 |
B3GALT6,NAT14,LEMD2,GOLM1,POMP,SLC12A9,REEP4,KCNAB2 |
| 2.885e-03 | -5.85 | DCUN1D4 (defective in cullin neddylation 1 domain containing 4) | protein interactions | 23142 | 17 | 8 | 17029 | 2761 |
RBX1,VAV2,BUD31,CUL3,TOP3A,CUL1,UBE2M,CAND1 |
| 2.885e-03 | -5.85 | CHD5 (chromodomain helicase DNA binding protein 5) | protein interactions | 26038 | 17 | 8 | 17029 | 2761 |
SUB1,MTA1,MTA2,MBD2,EIF5,RBBP4,MBD3,HDAC2 |
| 2.887e-03 | -5.85 | tricarboxylic acid metabolic process | biological process | GO:0072350 | 38 | 13 | 17256 | 2622 |
SDHB,SUCLG1,MDH2,IDH3A,ACLY,CS,SUCLG2,DHTKD1,MDH1,GLUD1,OGDH,IDH3B,SDHA |
| 2.887e-03 | -5.85 | transcription by RNA polymerase I | biological process | GO:0006360 | 38 | 13 | 17256 | 2622 |
UBTF,RRN3,POLR2L,CD3EAP,POLR2K,BAZ2A,SMARCA4,POLR1B,GTF2H2,ZNRD1,TTF1,TWISTNB,MAPK3 |
| 2.887e-03 | -5.85 | negative regulation of extrinsic apoptotic signaling pathway via death domain receptors | biological process | GO:1902042 | 38 | 13 | 17256 | 2622 |
TNFAIP3,RAF1,DAPK1,RFFL,ARHGEF2,HMGB2,BRCA1,BCL2L1,PARK7,TMBIM1,FADD,FAS,CFLAR |
| 2.893e-03 | -5.85 | UDAYAKUMAR_MED1_TARGETS_DN | MSigDB lists | UDAYAKUMAR_MED1_TARGETS_DN | 220 | 49 | 17377 | 2626 |
MBD1,PPP1R12A,REPS2,TSC22D3,FAM53C,RHOC,UROD,TRIO,RGS2,MAP1LC3B,DNAJB9,CREM,DLG5,MDM2,PTEN,PRDM4,ADCY9,JOSD1,TTC17,CITED2,SAP30L,TMBIM1,RYBP,SPTAN1,IFRD1,PPP3CA,ADAM17,TRAFD1,RB1CC1,ERF,CAMSAP1,FRAT2,MAP7D1,PTTG1IP,CCNF,KDM3A,PICALM,RHOB,USP36,FAS,GNAS,UPF1,BRD2,ETS2,GADD45B,KHSRP,CANT1,SPCS3,FUBP1 |
| 2.902e-03 | -5.84 | GSE3982_CTRL_VS_LPS_4H_MAC_DN | MSigDB lists | GSE3982_CTRL_VS_LPS_4H_MAC_DN | 193 | 44 | 17377 | 2626 |
GPR132,EWSR1,AGRN,PLAGL2,TIA1,BCL2L1,EIF1B,BIRC2,CDC73,CFLAR,ABL2,CLIC4,SP100,ITGB8,SAR1A,ATP13A3,RRBP1,DCP1A,CREB1,TIPARP,TMX1,BAK1,TNFAIP3,NEK7,EZR,PRPF3,KLF6,PSMB9,CYB5A,TFEB,FAS,NECAP2,SLCO4A1,MTHFD2,GOLGA4,GADD45B,STAT1,SIAH2,NUP62,PITPNA,TICAM1,RPS6KC1,HIPK3,IFI16 |
| 2.902e-03 | -5.84 | GSE360_T_GONDII_VS_B_MALAYI_HIGH_DOSE_MAC_UP | MSigDB lists | GSE360_T_GONDII_VS_B_MALAYI_HIGH_DOSE_MAC_UP | 193 | 44 | 17377 | 2626 |
MIF,SRM,IER2,PTMS,ATXN3,MPHOSPH8,NDUFB6,SRGN,UCK2,MED13L,ARFIP2,NCKAP1,SPR,TFAP4,HOMER1,KDM2A,ATP2A2,MCM5,SIVA1,MSH2,CYC1,MAP3K14,IMPA2,MSH6,SLC25A1,PDPK1,TELO2,PPFIA3,NFATC2IP,MEN1,MCM2,ICMT,MBD3,H2AFV,TRIM28,SNRPA,ADSS,GOLGA8A,RUVBL2,HRAS,BYSL,B4GALT2,PFKP,SSRP1 |
| 2.902e-03 | -5.84 | KAECH_NAIVE_VS_DAY15_EFF_CD8_TCELL_DN | MSigDB lists | KAECH_NAIVE_VS_DAY15_EFF_CD8_TCELL_DN | 193 | 44 | 17377 | 2626 |
TXN,GMFG,SEC61G,SRGN,PTTG1,RACGAP1,STMN1,HLA-A,RPA2,CAPN2,VMP1,MBD2,LPIN2,RRBP1,FAM89B,RPAP1,MDFIC,CLDND1,F2R,DNMT1,S100A6,LYPLA2,MAPRE2,POLR2L,KLF10,ELL2,TSPAN31,EMP3,MAP7D1,KRTCAP2,PRDX1,MYO1F,NUCB1,IDE,AHNAK,TMED10,ITGB1,H2AFX,HMGB2,ACTB,ATF6,CHPT1,CCNB2,TERF1 |
| 2.902e-03 | -5.84 | DNA/RNA_helicase_DEAH_CS | interpro domains | IPR002464 | 22 | 9 | 18492 | 2768 |
DHX16,CHD3,DHX29,CHD1L,DHX9,DHX8,BLM,DHX57,DHX15 |
| 2.905e-03 | -5.84 | TRIM38 (tripartite motif containing 38) | protein interactions | 10475 | 28 | 11 | 17029 | 2761 |
UBE2D3,UBE2E2,TSPYL4,TAB2,ATXN1,GORASP2,TICAM1,GMCL1,AZI2,UBE2I,EIF1B |
| 2.905e-03 | -5.84 | MTX2 (metaxin 2) | protein interactions | 10651 | 28 | 11 | 17029 | 2761 |
CHCHD3,IMMT,MTX3,HNRNPR,PHB2,VDAC2,KRAS,NDUFA4,MTX1,APOOL,CHCHD6 |
| 2.905e-03 | -5.84 | PRRC1 (proline rich coiled-coil 1) | protein interactions | 133619 | 28 | 11 | 17029 | 2761 |
PLK1,FYTTD1,PPIB,RHOA,HARS,PIN1,PSMG1,MCM2,RAB1A,CUTC,APP |
| 2.905e-03 | -5.84 | CHD7 (chromodomain helicase DNA binding protein 7) | protein interactions | 55636 | 28 | 11 | 17029 | 2761 |
ARID2,MTA1,MTA2,SMARCA4,CTCF,BRD7,ARID1A,PBRM1,WDR5,SMARCE1,TERF2 |
| 2.906e-03 | -5.84 | glycolipid metabolic process | biological process | GO:0006664 | 124 | 31 | 17256 | 2622 |
PGAP2,PIGM,PIGN,PIGT,DPM1,GALC,PIGQ,HEXB,CERK,GBA,ASAH1,SUMF1,ESYT1,ARSK,NEU1,CREM,ITGB8,PYURF,PIGG,ST3GAL2,GLTP,CTSA,SMPD4,PSAP,CLN3,B4GALT3,ST8SIA2,CLN6,HEXA,GM2A,ESYT2 |
| 2.906e-03 | -5.84 | liposaccharide metabolic process | biological process | GO:1903509 | 124 | 31 | 17256 | 2622 |
PGAP2,PIGM,PIGN,PIGT,DPM1,GALC,PIGQ,HEXB,CERK,GBA,ASAH1,SUMF1,ESYT1,ARSK,NEU1,CREM,ITGB8,PYURF,PIGG,ST3GAL2,GLTP,CTSA,SMPD4,PSAP,CLN3,B4GALT3,ST8SIA2,CLN6,HEXA,GM2A,ESYT2 |
| 2.911e-03 | -5.84 | lung-carcinoma-mixed_adenosquamous_carcinoma | COSMIC cancer mutations | lung-carcinoma-mixed_adenosquamous_carcinoma | 111 | 28 | 17385 | 2587 |
DCAF6,MAX,DNMT3A,NRAS,ATG9A,VHL,SF3B1,SMARCA4,KLC1,KRAS,KMT2C,EML4,HEATR5B,GNAS,KIF5B,FGFR3,HLA-B,RB1,PTEN,CCDC6,ATIC,PTPN11,STK11,TFG,ASB6,HRAS,SMAD4,CDKN2A |
| 2.914e-03 | -5.84 | GO_HISTONE_METHYLTRANSFERASE_ACTIVITY | MSigDB lists | GO_HISTONE_METHYLTRANSFERASE_ACTIVITY | 47 | 15 | 17377 | 2626 |
ASH1L,SUV39H2,SUZ12,SETD3,CXXC1,EHMT1,PRMT7,WDR82,EZH1,MEN1,WDR5,FBL,PRMT2,CARM1,DOT1L |
| 2.914e-03 | -5.84 | REACTOME_VIF_MEDIATED_DEGRADATION_OF_APOBEC3G | MSigDB lists | REACTOME_VIF_MEDIATED_DEGRADATION_OF_APOBEC3G | 47 | 15 | 17377 | 2626 |
PSMD2,PSMD1,PSMA6,PSMA8,RBX1,RPS27A,PSMD8,PSMD3,PSMB7,PSMA1,PSMB9,PSMD9,PSMC1,PSMB3,PSMC4 |
| 2.914e-03 | -5.84 | MODULE_312 | MSigDB lists | MODULE_312 | 47 | 15 | 17377 | 2626 |
PLK1,PCNA,NRAS,BIRC3,BIRC5,E2F1,E2F3,MKI67,MYBL2,BCL2L1,CCNB1,STK17B,BIRC2,CFLAR,FAS |
| 2.914e-03 | -5.84 | JAZAERI_BREAST_CANCER_BRCA1_VS_BRCA2_UP | MSigDB lists | JAZAERI_BREAST_CANCER_BRCA1_VS_BRCA2_UP | 47 | 15 | 17377 | 2626 |
PAF1,GART,MAPRE1,CTNNBL1,PPP2R5A,COPA,HARS,TATDN2,TUFM,NOC2L,SPCS3,RBBP4,PEF1,GNB2,FDFT1 |
| 2.915e-03 | -5.84 | ATXN1 (ataxin 1) | protein interactions | 6310 | 257 | 59 | 17029 | 2761 |
USP7,UNK,NCOR2,IMMT,TOMM20,ARID5A,CDIP1,SLC4A2,GGA2,DAZAP2,UBE2I,EIF1B,MYEF2,YY1AP1,CREM,ZNF804A,CCNK,ADD3,SAR1A,ELP5,SLC25A51,ANP32A,AHDC1,CRY2,KIF22,LRSAM1,ANKHD1,ATP6V0D1,KCNAB2,CFL1,MLST8,UBQLN4,PRRC2A,CIC,LDB1,EHMT1,SUGP2,CIRBP,ATXN1,SUPT20H,TOLLIP,RCC1L,TSC1,EIF4ENIF1,HSPA4,ZHX1,MED15,MYO18A,ZC3H7B,PML,UHRF2,ATXN2L,PQBP1,KMT2B,YWHAZ,TRIM32,PPP6R2,COIL,OAZ1 |
| 2.917e-03 | -5.84 | GO_TRANSFERASE_ACTIVITY_TRANSFERRING_ONE_CARBON_GROUPS | MSigDB lists | GO_TRANSFERASE_ACTIVITY_TRANSFERRING_ONE_CARBON_GROUPS | 177 | 41 | 17377 | 2626 |
ASH1L,DNMT3A,NOP2,CXXC1,SUZ12,EZH1,WDR5,METTL3,IRF4,GART,SUV39H2,METTL14,ATIC,PRDM4,FAM86C1,FBL,DNMT1,NSUN4,FTSJ3,CARM1,METTL1,HEMK1,EHMT1,NSUN2,METTL5,METTL2A,WDR82,EDF1,METTL22,PRMT2,MEN1,ICMT,MTR,PRDM11,DOT1L,SETD3,WDR4,CAMKMT,FTSJ1,PRMT7,GCSH |
| 2.918e-03 | -5.84 | IKBKG (inhibitor of nuclear factor kappa B kinase subunit gamma) | protein interactions | 8517 | 325 | 72 | 17029 | 2761 |
MIB2,USP7,TRIM41,CYLD,RAB11B,RBM8A,TPX2,CUL1,INO80E,LYN,KCMF1,GIT2,BIRC2,PA2G4,PRKD3,TXLNA,NSFL1C,TNPO2,MAVS,GCC1,CCAR1,TRIM14,CDC37,PLK1,SEPT9,BIRC3,PBXIP1,POLR2D,GLO1,ZFAND5,ERC1,GINS4,OPTN,PPP2CA,HSPA4,TAB2,FKBP5,ABCA1,DDX58,UBE2D3,MCM10,MAPRE1,LZTR1,CASP6,KLHL21,CENPF,GADD45G,KIF23,RACGAP1,CDK13,ARGLU1,WDR5,DNAJC8,MZT2A,RBM34,TANK,DAPK1,KANSL2,BCL2,MAP3K14,FRMD8,LUC7L2,RPAP3,RHOA,TNFAIP3,USP10,FADD,PFDN5,KPNA1,TRIM26,CDK2,PARP10 |
| 2.933e-03 | -5.83 | soft_tissue-fibrous_tissue_and_uncertain_origin-gastrointestinal_stromal_tumour | COSMIC cancer mutations | soft_tissue-fibrous_tissue_and_uncertain_origin-gastrointestinal_stromal_tumour | 76 | 21 | 17385 | 2587 |
ERMP1,NRAS,NCK1,NF1,SF3B1,KRAS,MAP2K2,DAPK3,GNAS,RB1,SGSH,PTEN,PTPN11,TIMELESS,H3F3A,CLN3,STAT3,PGAM1,HRAS,CDKN2A,ABCC5 |
| 2.940e-03 | -5.83 | cellular response to reactive nitrogen species | biological process | GO:1902170 | 18 | 8 | 17256 | 2622 |
CCNA2,GUCY1B1,STAT6,DNM2,MAP3K5,CDK2,MTR,CFLAR |
| 2.940e-03 | -5.83 | aerobic electron transport chain | biological process | GO:0019646 | 18 | 8 | 17256 | 2622 |
COX15,COX5B,COX7A2L,COX8A,COX5A,CYCS,COX4I1,NDUFA4 |
| 2.940e-03 | -5.83 | mitochondrial electron transport, cytochrome c to oxygen | biological process | GO:0006123 | 18 | 8 | 17256 | 2622 |
COX15,COX5B,COX7A2L,COX8A,COX5A,CYCS,COX4I1,NDUFA4 |
| 2.940e-03 | -5.83 | positive regulation of autophagy of mitochondrion | biological process | GO:1903599 | 18 | 8 | 17256 | 2622 |
ATP5IF1,FBXO7,GBA,SMURF1,PARK7,CDC37,MFN2,OPTN |
| 2.940e-03 | -5.83 | septin cytoskeleton organization | biological process | GO:0032185 | 18 | 8 | 17256 | 2622 |
SEPT11,TMEM250,SEPT8,SEPT1,SEPT9,SEPT7,ANLN,RTKN |
| 2.946e-03 | -5.83 | BIOCARTA_GPCR_PATHWAY | MSigDB lists | BIOCARTA_GPCR_PATHWAY | 34 | 12 | 17377 | 2626 |
GNAS,CALM2,PPP3CA,NFATC3,RAF1,PRKAR1B,NFATC2,PPP3CB,ELK1,CREB1,HRAS,MAPK3 |
| 2.946e-03 | -5.83 | KEGG_CYSTEINE_AND_METHIONINE_METABOLISM | MSigDB lists | KEGG_CYSTEINE_AND_METHIONINE_METABOLISM | 34 | 12 | 17377 | 2626 |
MAT2B,SRM,DNMT3A,GOT2,AMD1,LDHA,AHCY,AHCYL1,MTR,DNMT1,MAT2A,LDHB |
| 2.946e-03 | -5.83 | GO_NEURON_APOPTOTIC_PROCESS | MSigDB lists | GO_NEURON_APOPTOTIC_PROCESS | 34 | 12 | 17377 | 2626 |
CDK5,RB1,MAX,PIGT,SIAH1,HDAC7,BCL2,BCL2L1,PSEN1,APP,FADD,FAS |
| 2.946e-03 | -5.83 | GO_MEMBRANE_PROTEIN_PROTEOLYSIS | MSigDB lists | GO_MEMBRANE_PROTEIN_PROTEOLYSIS | 34 | 12 | 17377 | 2626 |
ADAM17,ADAM10,APH1A,RBMX,MYH9,ADAM9,PARL,APH1B,PSEN1,SPPL2B,RHBDD1,SPPL2A |
| 2.946e-03 | -5.83 | GO_NEGATIVE_REGULATION_OF_MRNA_METABOLIC_PROCESS | MSigDB lists | GO_NEGATIVE_REGULATION_OF_MRNA_METABOLIC_PROCESS | 34 | 12 | 17377 | 2626 |
HNRNPA2B1,SYNCRIP,RBM42,RBMX,SRSF6,SRSF4,RNPS1,CTR9,SECISBP2,PABPC1,TOB1,SRSF10 |
| 2.946e-03 | -5.83 | GO_NEGATIVE_REGULATION_OF_EXTRINSIC_APOPTOTIC_SIGNALING_PATHWAY_VIA_DEATH_DOMAIN_RECEPTORS | MSigDB lists | GO_NEGATIVE_REGULATION_OF_EXTRINSIC_APOPTOTIC_SIGNALING_PATHWAY_VIA_DEATH_DOMAIN_RECEPTORS | 34 | 12 | 17377 | 2626 |
TNFAIP3,RAF1,DAPK1,ARHGEF2,RFFL,HMGB2,BRCA1,PARK7,TMBIM1,FADD,FAS,CFLAR |
| 2.948e-03 | -5.83 | Ub-specific processing proteases | REACTOME pathways | R-HSA-5689880 | 223 | 53 | 10287 | 1696 |
DDX58,USP7,TOMM20,CYLD,CLSPN,USP48,PSMD9,BECN1,BIRC2,WDR48,USP5,MAT2B,PSMD2,MDM2,PSMD1,PSMA6,CCNA2,CCP110,PTEN,AXIN2,USP34,BIRC3,KAT2A,PSMA8,USP42,PSMB7,VDAC2,PSMA1,USP10,USP22,ADRB2,VDAC1,RHOT1,PSMB9,USP21,PSMB3,PSMC4,HGS,KEAP1,IDE,SMAD2,RPS27A,PSMD8,AXIN1,PSMD3,SIAH2,USP20,SMAD1,USP11,ARRB2,PSMC1,SMAD4,USP13 |
| 2.949e-03 | -5.83 | NDUFB10 (NADH:ubiquinone oxidoreductase subunit B10) | protein interactions | 4716 | 40 | 14 | 17029 | 2761 |
NDUFA5,NDUFV2,NDUFV1,UPF1,NDUFS1,TIMMDC1,NDUFB9,NDUFA4,CYC1,NDUFS5,MRPL13,BCAP31,NDUFS7,NDUFS4 |
| 2.949e-03 | -5.83 | RPL3L (ribosomal protein L3 like) | protein interactions | 6123 | 40 | 14 | 17029 | 2761 |
PTPN2,RPS2,RPL6,RPL8,RPL15,RPL19,RPL27A,RPS26,RPS9,APP,PABPC4,RPL11,RPL23A,RPL36 |
| 2.949e-03 | -5.83 | GNL3L (G protein nucleolar 3 like) | protein interactions | 54552 | 40 | 14 | 17029 | 2761 |
SRP72,MDM2,SMC3,FTSJ1,OLA1,GTPBP4,TOR1AIP2,KRAS,TGOLN2,BRCA1,ADRB2,FTSJ3,TERF1,NMD3 |
| 2.949e-03 | -5.83 | FABP5 (fatty acid binding protein 5) | protein interactions | 2171 | 40 | 14 | 17029 | 2761 |
FKBP1A,CYLD,HINT1,PIN1,TKT,AKR1B1,EZR,RBM3,GLO1,TAGLN2,MCM2,PCGF1,ATP5PF,PGAM1 |
| 2.949e-03 | -5.83 | SRA1 (steroid receptor RNA activator 1) | protein interactions | 10011 | 40 | 14 | 17029 | 2761 |
FGFR1OP,ETS2,POLK,BTG2,E2F3,UBE2Z,CREB1,ATF2,GTF2H2,RUFY1,ETS1,OAZ1,HDAC2,SAP30 |
| 2.949e-03 | -5.83 | YTHDF2 (YTH N6-methyladenosine RNA binding protein 2) | protein interactions | 51441 | 40 | 14 | 17029 | 2761 |
RPA2,CUL3,TARDBP,SEPT7,MCM2,POT1,APP,EIF3H,EIF3A,RPA1,DCTN1,USP5,CAND1,USP13 |
| 2.949e-03 | -5.83 | ARCN1 (archain 1) | protein interactions | 372 | 40 | 14 | 17029 | 2761 |
KEAP1,COPA,TMED10,SF3B1,COPE,WBP2,TMEM216,KLC1,CNTROB,MCM2,APP,COPG2,COPB2,CDC5L |
| 2.949e-03 | -5.83 | TIA1 (TIA1 cytotoxic granule associated RNA binding protein) | protein interactions | 7072 | 40 | 14 | 17029 | 2761 |
DDX58,CXXC4,POLK,ELL2,FASTK,CUL3,CUL1,PITPNB,SRSF3,PCBP1,PCBP2,HTRA2,LUC7L2,CAND1 |
| 2.949e-03 | -5.83 | GPATCH8 (G-patch domain containing 8) | protein interactions | 23131 | 40 | 14 | 17029 | 2761 |
TIMM8B,PON2,TIMM13,EWSR1,APH1A,CLK3,RNPS1,ATXN1,PCGF1,LUC7L,TMEM165,PIP4K2A,LUC7L2,TERF2 |
| 2.951e-03 | -5.83 | REL (REL proto-oncogene, NF-kB subunit) | protein interactions | 5966 | 216 | 51 | 17029 | 2761 |
KIAA0100,DHPS,MAP3K7CL,EIF3D,GADD45G,SLC39A13,UBE2Z,CHCHD2,NKRF,MIEN1,TMEM165,VPS25,MAD2L2,NEIL2,PAPOLA,CDKN2C,FLAD1,SNRNP25,CLIC4,HDAC7,EXOSC1,OSTF1,TMEM8A,MVP,C12orf75,MTPN,CGGBP1,EIF5A,BIRC3,POLR2L,ATG9A,MEMO1,PSMA1,ADSL,RABIF,ATXN1,ADRB2,SEPT7,EIF3A,CHAF1A,SEC31A,NUCB1,HSPA4,TMEM268,C1orf109,NDE1,CDK2,TSTD2,AAAS,ZNF564,NXT2 |
| 2.974e-03 | -5.82 | GO_PHAGOCYTOSIS | MSigDB lists | GO_PHAGOCYTOSIS | 156 | 37 | 17377 | 2626 |
WASF2,RAB14,ACTR3,VAV2,RAC1,MYH9,JMJD6,CDC42SE2,NCKAP1,CSNK1A1,BECN1,LYN,PIP5K1C,VAV1,CDC42,ARPC5,PIK3R2,CORO1A,PDIA6,ABI1,CYFIP1,NCK1,RAB7A,WIPF1,EIF2AK1,CYFIP2,ARPC1A,MAPK3,WAS,ELMO1,CORO1C,LIMK1,ACTB,SCARB1,MAPK1,ABCA1,ANXA11 |
| 2.976e-03 | -5.82 | Wnt signaling pathway, planar cell polarity pathway | biological process | GO:0060071 | 99 | 26 | 17256 | 2622 |
RHOA,CELSR2,PSMA8,RAC1,PSMB7,PSMA1,ZNRF3,PSMB9,PSMD9,FZD6,PSMB3,PSMC4,PSMD2,PSMA6,PSMD1,CDC42,RPS27A,PSMD8,PSMD3,AP2B1,DVL1,SMURF1,ARRB2,AP2S1,PSMC1,DVL2 |
| 2.977e-03 | -5.82 | ACOSTA_PROLIFERATION_INDEPENDENT_MYC_TARGETS_UP | MSigDB lists | ACOSTA_PROLIFERATION_INDEPENDENT_MYC_TARGETS_UP | 75 | 21 | 17377 | 2626 |
DDX28,AATF,NQO1,GNPDA1,KIAA0930,UCK2,PSMG1,SLC29A1,ODC1,CUTC,CD320,GLOD4,NUP210,PEX5,FBXO41,EIF4A3,MTMR4,MAST2,PDCD11,GCSH,PRPF19 |
| 2.980e-03 | -5.82 | SEP | smart domains | SM00553 | 3 | 3 | 9493 | 1367 |
UBXN2A,UBXN2B,NSFL1C |
| 2.983e-03 | -5.81 | COPE (coatomer protein complex subunit epsilon) | protein interactions | 11316 | 57 | 18 | 17029 | 2761 |
COPA,TRIP10,COPE,WBP2,BRCA1,ARF1,MCFD2,VDAC1,COPG2,COPB2,SF3B2,KIF5B,TMED10,MCM5,PPM1G,XRCC3,SRSF3,LMAN1 |
| 2.983e-03 | -5.81 | DHX38 (DEAH-box helicase 38) | protein interactions | 9785 | 57 | 18 | 17029 | 2761 |
CDC40,CYLD,COPA,PRKDC,RBM8A,CUL3,RNPS1,USP39,CSNK2A1,KRAS,JMJD6,SNRPD3,PITHD1,TERF2IP,DHX16,CWC27,MFAP1,DDX5 |
| 2.983e-03 | -5.81 | CLIC1 (chloride intracellular channel 1) | protein interactions | 1192 | 57 | 18 | 17029 | 2761 |
EWSR1,ST13,PSMA1,ATP6V0A1,SDF2L1,CAPZA2,BRCA1,ANLN,ISG15,MTHFD2,ZNF302,RPLP1,NUP62,ATP6V0C,ATF2,ARRB2,CDK2,DDB1 |
| 2.983e-03 | -5.81 | ATP6V0A2 (ATPase H+ transporting V0 subunit a2) | protein interactions | 23545 | 57 | 18 | 17029 | 2761 |
ANKLE2,RPS15,RPS2,ACP2,ANXA6,TYW1,ATP6V0A1,ATP6V1B2,REEP5,TMCC3,ATP6V1D,ZNRF2,CLCN6,ATP6V0C,ATP6V1C1,B4GALT3,ATP6V0E1,ATP6V0D1 |
| 2.983e-03 | -5.81 | VPS53 (VPS53, GARP complex subunit) | protein interactions | 55275 | 57 | 18 | 17029 | 2761 |
CCDC93,USP7,MAX,RPRD1A,THOC1,RCOR1,NUF2,ARMH3,RAB1A,PSMD9,GIT2,HMG20A,OIP5,GRIPAP1,SNAP29,RABGAP1L,ARNTL,PTAR1 |
| 2.983e-03 | -5.81 | PSTPIP1 (proline-serine-threonine phosphatase interacting protein 1) | protein interactions | 9051 | 57 | 18 | 17029 | 2761 |
WASF2,RPL29,RPL35,PTPN18,WIPF1,BZW2,RPL36,RPL23A,WAS,RPL32,KMT5C,ATIC,TULP3,DNM2,ACTB,MVP,TUBB,FDFT1 |
| 2.983e-03 | -5.81 | CHD8 (chromodomain helicase DNA binding protein 8) | protein interactions | 57680 | 57 | 18 | 17029 | 2761 |
CTDP1,BRD4,WDR18,CTCF,NSD3,NFATC2IP,WDR5,PIP4K2A,LMNA,USF1,KPNA1,CDC27,UHRF2,CREB1,TERF1,MSH6,TERF2,CDC5L |
| 2.983e-03 | -5.81 | SAE1 (SUMO1 activating enzyme subunit 1) | protein interactions | 10055 | 57 | 18 | 17029 | 2761 |
TP53RK,EWSR1,DHPS,SUMO2,USP39,ADSL,KRAS,RANGAP1,UBE2I,APP,NPLOC4,TPD52L2,WAS,WDR4,PQBP1,FUS,UBE2M,RPRD1B |
| 2.994e-03 | -5.81 | site of DNA damage | cellular component | GO:0090734 | 39 | 13 | 18223 | 2701 |
RFWD3,RPA2,PAXX,RAD18,POLK,HELB,H2AFX,SMC6,ATF2,SLF1,SLF2,RNF169,PRPF19 |
| 2.999e-03 | -5.81 | GO_REGULATION_OF_PROTEIN_SERINE_THREONINE_KINASE_ACTIVITY | MSigDB lists | GO_REGULATION_OF_PROTEIN_SERINE_THREONINE_KINASE_ACTIVITY | 457 | 91 | 17377 | 2626 |
CCNC,BCCIP,TRAF7,NF1,RAF1,MAGED1,CCNL2,S1PR2,MAPK14,DUSP22,LYN,CRKL,CALM2,CDKN2C,RAP1A,CCNA2,SHC1,RALB,CDKN1B,F2R,CDK12,DVL2,CDC37,COPS8,PLK1,PSRC1,CUL3,LRP5,CDC6,DNAJA1,PKMYT1,PPP2CA,MAP3K4,HHEX,TAB2,RPS27A,AXIN1,STK38,GADD45B,CAB39,ADAM9,STK11,MAPK1,PDCD4,MIF,ZFP91,GADD45G,PRKAA1,CIB1,BLM,RGS2,PSEN1,TFAP4,CCNK,PDCD10,PTEN,FBXO7,PTPN11,H2AFY,MDFIC,MAP3K14,GNAI2,TGFB1,TELO2,ADAM17,RHOA,TNFAIP3,MAPKAPK3,PRKAR1B,GTPBP4,GBA,MAP4K3,KRAS,MEN1,MAP2K2,MAPK3,MBIP,HGS,GPS2,CSK,DUSP3,NUP62,PKD2,MAP3K5,NR2F2,UBE2C,CD81,HIPK3,HRAS,CDKN2A,ALS2 |
| 3.002e-03 | -5.81 | TDRD3 (tudor domain containing 3) | protein interactions | 81550 | 32 | 12 | 17029 | 2761 |
EWSR1,THOC1,POC1A,RBM8A,RNPS1,FUS,SND1,FXR1,PABPC1,DHX15,POLR2A,DCTN1 |
| 3.002e-03 | -5.81 | NOB1 (NIN1 (RPN12) binding protein 1 homolog) | protein interactions | 28987 | 32 | 12 | 17029 | 2761 |
RPS2,VHL,RPS14,POC1A,UPF2,ANKHD1,FTSJ3,APP,PNO1,CSNK1D,BYSL,PRNP |
| 3.002e-03 | -5.81 | SEPT3 (septin 3) | protein interactions | 55964 | 32 | 12 | 17029 | 2761 |
SEPT1,SEPT9,WDYHV1,DNAAF2,MAPK6,MRPL12,WBP2,WDTC1,SEPT8,SEPT11,SEPT7,MOB1A |
| 3.002e-03 | -5.81 | ARID4B (AT-rich interaction domain 4B) | protein interactions | 51742 | 32 | 12 | 17029 | 2761 |
SAP130,FOXK1,PHF23,KIF11,ETS1,SINHCAF,RPS26,ARID4A,MXD1,DDB1,HDAC2,SAP30 |
| 3.002e-03 | -5.81 | HIST1H2AE (histone cluster 1 H2A family member e) | protein interactions | 3012 | 32 | 12 | 17029 | 2761 |
COX15,TONSL,HUWE1,EID1,SUZ12,CUL1,NAP1L4,MCM2,VDAC1,SDHA,PARK7,CAND1 |
| 3.002e-03 | -5.81 | SCYL1 (SCY1 like pseudokinase 1) | protein interactions | 57410 | 32 | 12 | 17029 | 2761 |
POLA2,SEC31A,CWC27,NEK7,CHD1L,SCYL1,AGPAT3,GORAB,CCNF,SMURF1,COIL,APP |
| 3.002e-03 | -5.81 | COQ6 (coenzyme Q6, monooxygenase) | protein interactions | 51004 | 32 | 12 | 17029 | 2761 |
BOLA3,COQ4,COQ8A,MLYCD,CHCHD2,CYCS,NIT2,CDK2,MRPL13,ATP5PF,APP,ECH1 |
| 3.002e-03 | -5.81 | RPL37 (ribosomal protein L37) | protein interactions | 6167 | 32 | 12 | 17029 | 2761 |
RPS15,DDX56,MDM2,MFAP1,TCF3,RTF1,POLR1B,BLM,CDK2,RPS9,APP,SRPK2 |
| 3.002e-03 | -5.81 | ZNF550 (zinc finger protein 550) | protein interactions | 162972 | 32 | 12 | 17029 | 2761 |
PPP2CA,TRIM41,MDM2,LTBP4,STRIP1,YTHDC2,STRN4,LRRC1,ERBIN,PPP2R2D,ZNF92,USP34 |
| 3.002e-03 | -5.81 | TCL1B (T cell leukemia/lymphoma 1B) | protein interactions | 9623 | 32 | 12 | 17029 | 2761 |
MED8,MED10,CCDC6,AKT2,HPS5,MED15,STRN4,IMPDH1,TNPO2,NDE1,APP,MED22 |
| 3.002e-03 | -5.81 | COX4I2 (cytochrome c oxidase subunit 4I2) | protein interactions | 84701 | 5 | 4 | 17029 | 2761 |
KRAS,COA3,CYCS,APP |
| 3.002e-03 | -5.81 | RITA1 (RBPJ interacting and tubulin associated 1) | protein interactions | 84934 | 5 | 4 | 17029 | 2761 |
DCP1A,RBPJ,GOLGA2,APP |
| 3.002e-03 | -5.81 | NAV3 (neuron navigator 3) | protein interactions | 89795 | 5 | 4 | 17029 | 2761 |
TFAP4,KRAS,MAPRE1,TRIO |
| 3.002e-03 | -5.81 | ZNF391 (zinc finger protein 391) | protein interactions | 346157 | 5 | 4 | 17029 | 2761 |
TMEM159,AGTRAP,RTN3,ARL6IP1 |
| 3.002e-03 | -5.81 | RGPD1 (RANBP2-like and GRIP domain containing 1) | protein interactions | 400966 | 5 | 4 | 17029 | 2761 |
RPAP3,CEP63,MCM2,SASS6 |
| 3.002e-03 | -5.81 | MT1X (metallothionein 1X) | protein interactions | 4501 | 5 | 4 | 17029 | 2761 |
TERF2IP,VKORC1,POT1,TERF1 |
| 3.002e-03 | -5.81 | Arhgef7 (Rho guanine nucleotide exchange factor (GEF7)) | protein interactions | 54126 | 5 | 4 | 17029 | 2761 |
SMAD2,CDC42,SMURF1,SMAD4 |
| 3.002e-03 | -5.81 | Trim32 (tripartite motif-containing 32) | protein interactions | 69807 | 5 | 4 | 17029 | 2761 |
UBE2I,NSF,KIF14,PRDX5 |
| 3.002e-03 | -5.81 | Gdi2 (guanosine diphosphate (GDP) dissociation inhibitor 2) | protein interactions | 14569 | 5 | 4 | 17029 | 2761 |
RAB6A,RAB1A,PTEN,RAB4A |
| 3.004e-03 | -5.81 | - | gene3d domains | 3.30.230.10 | 21 | 9 | 8148 | 1295 |
GALK1,RPS2,EFTUD2,PMS2,TOP2B,EFL1,GALK2,LONP2,GFM2 |
| 3.008e-03 | -5.81 | MSH3 (mutS homolog 3) | protein interactions | 4437 | 36 | 13 | 17029 | 2761 |
RPA2,SLC39A9,SNX8,KARS,PCNA,CDC42,XPA,PMS2,MSH2,UHRF2,BRCA1,MSH6,RPA1 |
| 3.008e-03 | -5.81 | HPRT1 (hypoxanthine phosphoribosyltransferase 1) | protein interactions | 3251 | 36 | 13 | 17029 | 2761 |
PA2G4,EWSR1,ANXA6,WDYHV1,CUL3,ANXA5,FUS,GPI,PTGES3,NANS,MCM2,EIF1B,PPA1 |
| 3.008e-03 | -5.81 | CHMP4A (charged multivesicular body protein 4A) | protein interactions | 29082 | 36 | 13 | 17029 | 2761 |
ADSS,COX15,PDCD6IP,CHMP4A,DCK,CDCA3,CHMP4B,CDK13,VPS4A,TFG,TALDO1,F2R,ARL6IP6 |
| 3.008e-03 | -5.81 | Anapc2 (anaphase promoting complex subunit 2) | protein interactions | 99152 | 36 | 13 | 17029 | 2761 |
TRIM4,SNX27,CDC16,CDC27,CENPF,CUL1,RRM2,LETMD1,ANAPC2,ANAPC7,CDC23,ANAPC4,FBXO5 |
| 3.008e-03 | -5.81 | HIRIP3 (HIRA interacting protein 3) | protein interactions | 8479 | 36 | 13 | 17029 | 2761 |
HSPH1,GART,UGP2,SNX2,PPM1G,STAT1,RPL8,CSNK2A1,XPO7,APP,FAF1,SRPK2,GTF2F1 |
| 3.008e-03 | -5.81 | MOB1B (MOB kinase activator 1B) | protein interactions | 92597 | 36 | 13 | 17029 | 2761 |
ANKRD28,DST,CYLD,STK38,MAP4K4,PPP6C,PPP6R2,PPP6R3,MOB1A,CRLF3,PPP6R1,APP,LRCH1 |
| 3.008e-03 | -5.81 | PSMA8 (proteasome subunit alpha 8) | protein interactions | 143471 | 36 | 13 | 17029 | 2761 |
PSMD2,MDM2,PSMD1,PSMA6,PSMD8,PSMD3,PSMB7,PSMA1,MCM2,PSMB9,PSMC1,PSMB3,PSMC4 |
| 3.008e-03 | -5.81 | KMT2E (lysine methyltransferase 2E) | protein interactions | 55904 | 36 | 13 | 17029 | 2761 |
USP7,SART1,DDX24,ZNF768,OGT,USP10,CUL1,KRAS,VPS4A,YY1,CDK11B,RBBP4,CDK2 |
| 3.008e-03 | -5.81 | PPAN-P2RY11 (PPAN-P2RY11 readthrough) | protein interactions | 692312 | 36 | 13 | 17029 | 2761 |
NOL12,PPAN,NIFK,STAU1,RPS2,ZNF512,RPS14,RBM34,MAK16,ZC3H3,RBM4,ZC3HAV1,GPATCH4 |
| 3.008e-03 | -5.81 | TRAF3IP3 (TRAF3 interacting protein 3) | protein interactions | 80342 | 36 | 13 | 17029 | 2761 |
MOB4,PPP2CA,PDCD10,SP100,STRIP1,DYNLL1,CDCA7L,STRN4,SIKE1,GGPS1,CCT8,FGFR1OP2,SSSCA1 |
| 3.008e-03 | -5.81 | ANAPC10 (anaphase promoting complex subunit 10) | protein interactions | 10393 | 36 | 13 | 17029 | 2761 |
CDC16,SMAD2,CDC27,UTP15,CBWD1,ANAPC2,KRAS,ANAPC7,NAP1L4,CDC23,CCNB1,LRP8,ANAPC4 |
| 3.008e-03 | -5.81 | TNIP2 (TNFAIP3 interacting protein 2) | protein interactions | 79155 | 36 | 13 | 17029 | 2761 |
USP7,NCOR2,MKNK1,PDCD6IP,TNFAIP3,STK11,MAPK1,SMURF1,PSMD9,APP,SSSCA1,SRPK2,SMARCD1 |
| 3.008e-03 | -5.81 | COMMD2 (COMM domain containing 2) | protein interactions | 51122 | 36 | 13 | 17029 | 2761 |
CCDC93,COMMD10,ARHGAP17,PCM1,POC1A,MIA2,COMMD5,COMMD4,MCMBP,COMMD6,COMMD8,APP,VPS29 |
| 3.008e-03 | -5.81 | RBM22 (RNA binding motif protein 22) | protein interactions | 55696 | 36 | 13 | 17029 | 2761 |
EIF4A3,SUZ12,CEP55,PPIE,CUL3,KIFAP3,SNRPG,AQR,NKAPD1,RBM4,LUC7L2,PRNP,PRPF19 |
| 3.008e-03 | -5.81 | CC2D2A (coiled-coil and C2 domain containing 2A) | protein interactions | 57545 | 36 | 13 | 17029 | 2761 |
SRP72,STAU1,TRIM26,PCM1,NOP2,CCDC138,YTHDC2,GPATCH1,RPF2,YWHAH,ECH1,LMNA,HAUS8 |
| 3.008e-03 | -5.81 | I-SMAD binding | molecular function | GO:0070411 | 11 | 6 | 17224 | 2647 |
SMAD2,SMAD1,SMURF1,SMAD4,AXIN1,AXIN2 |
| 3.008e-03 | -5.81 | transcription factor activity, transcription factor recruiting | molecular function | GO:0001134 | 11 | 6 | 17224 | 2647 |
MYBL1,SNAPC4,SGF29,TTF1,MYBL2,CDC5L |
| 3.010e-03 | -5.81 | phagocytic vesicle | cellular component | GO:0045335 | 122 | 30 | 18223 | 2701 |
RAB14,CLCN3,RAB11B,RAB7A,HLA-E,RAB23,TAP1,ATP6V0A1,ITGB5,BECN1,RAB11A,RAB22A,HLA-A,KIF5B,HLA-B,RAB8A,ATP6V0B,RAP1A,WAS,VPS26B,SNAP23,DNM2,ATP6V0A2,TAP2,ATP6V0C,CORO1A,ATP6V0D1,ATP6V0E1,ABCA1,ANXA11 |
| 3.013e-03 | -5.80 | DYNC1H1 (dynein cytoplasmic 1 heavy chain 1) | protein interactions | 1778 | 146 | 37 | 17029 | 2761 |
USP7,UNK,COX15,MAX,MAPRE1,CYLD,SUZ12,DYNLL1,DCTN2,MCCC1,STRN4,RUFY1,RPA2,ZNF746,YBX1,CRY2,POC5,DCTN1,CDC5L,MKLN1,SNRPB,CUL3,RPS24,BICD2,BRCA1,MCM2,XRCC5,EPB41,EIF3K,SMAD2,SYNCRIP,RUVBL2,FUS,PLOD3,CDK2,ARRB2,DYNC1LI2 |
| 3.015e-03 | -5.80 | GSE7460_CTRL_VS_TGFB_TREATED_ACT_FOXP3_MUT_TCONV_UP | MSigDB lists | GSE7460_CTRL_VS_TGFB_TREATED_ACT_FOXP3_MUT_TCONV_UP | 188 | 43 | 17377 | 2626 |
WSB2,CMAS,FEZ2,PLXNC1,GXYLT1,NQO1,CASP6,ZFP91,RAC1,GYG1,LACTB2,ITGB5,LYRM2,STAM,KTN1,BCAP31,C2orf68,TFAP4,GSTK1,AXIN2,KIFAP3,TAGLN2,CITED2,LPCAT1,PHF10,PTPN18,POLR2G,NQO2,KIAA0930,SEPT8,PLEC,BSDC1,MTMR3,NUCB1,DNAJC10,DAP3,ITPRIPL1,AGPAT2,ACYP1,OSBPL8,MAP4,RBPJ,CD81 |
| 3.015e-03 | -5.80 | GSE17721_CTRL_VS_LPS_24H_BMDC_UP | MSigDB lists | GSE17721_CTRL_VS_LPS_24H_BMDC_UP | 188 | 43 | 17377 | 2626 |
CASP6,GNPDA1,MRPS15,TRIM11,RAC1,CENPF,HABP4,CUTA,HAUS4,XPR1,CDKN2C,PPP4R1,CAPZA1,SOCS6,CLCN6,CORO1A,PCBP2,MYO5A,MED22,ZNF189,ADCY7,PDLIM2,EIF3L,NEK7,USP42,RPL6,GALK2,CAPZA2,ARID1A,SMC2,ANLN,EIF3H,MAPK3,HAUS8,HHEX,GALNT2,PITX1,BCL7C,NCOA1,PDXK,GLCCI1,TSPAN5,SMARCD1 |
| 3.015e-03 | -5.80 | GSE17721_POLYIC_VS_PAM3CSK4_8H_BMDC_UP | MSigDB lists | GSE17721_POLYIC_VS_PAM3CSK4_8H_BMDC_UP | 188 | 43 | 17377 | 2626 |
NSMCE4A,TRIP12,TRIP10,FAM53C,DLGAP4,AP3M2,PXMP2,COMMD5,RLF,CHD1,CUTC,BZW2,ANKIB1,MBD4,GTF2F1,FAM192A,ATG3,RRBP1,CDKN1B,H2AFY,TFG,MOB1A,CTDSP2,KDM3B,PTPN18,FOXK1,CSRP1,KLF10,TSPAN31,TIGD5,BRCA1,ICAM2,GINS4,PDLIM1,HIPK2,RBMS1,MBD6,NAA20,SMAD4,TOB1,CBX4,STARD3NL,S100PBP |
| 3.015e-03 | -5.80 | GSE14308_TH17_VS_INDUCED_TREG_UP | MSigDB lists | GSE14308_TH17_VS_INDUCED_TREG_UP | 188 | 43 | 17377 | 2626 |
TCF12,FEZ2,GGNBP2,TRIP12,GSPT2,HABP4,OLA1,GYG1,FOXO3,PAIP2,DDRGK1,SPPL2A,MAN1A1,UBXN2A,NT5DC1,RPL17,PPP1R12C,ARL6IP1,SRI,RNF19A,SMC4,SRSF10,SP3,FYTTD1,PPP1R18,FAM172A,TSPYL4,TACC1,HELB,PRKDC,METTL5,POLR3GL,DNAJA1,PHF6,BRMS1,VPS26B,OSBPL8,OAZ2,DCAF11,RNF38,ADAM9,BTF3,C11orf1 |
| 3.015e-03 | -5.80 | GSE21927_SPLENIC_VS_TUMOR_MONOCYTES_FROM_C26GM_TUMOROUS_MICE_BALBC_DN | MSigDB lists | GSE21927_SPLENIC_VS_TUMOR_MONOCYTES_FROM_C26GM_TUMOROUS_MICE_BALBC_DN | 188 | 43 | 17377 | 2626 |
PRKAB1,FEZ2,CYLD,GMFG,TSC22D3,ACAP1,CREBL2,ARGLU1,CCNL2,CPNE3,C2orf68,ADD3,ATG13,TTC17,METTL9,MAML1,CITED2,ABI1,ABCC5,SPTAN1,SRSF11,GCC2,BAZ2A,CIRBP,FBXO9,PRPSAP1,MACF1,ARHGAP15,VEZF1,ZNF862,GOLGA8A,ARNTL,CTBS,BBX,ARAP1,TRIM52,TRAF5,TERF1,TOB1,LONP2,CSNK1D,N4BP2L2,S100PBP |
| 3.015e-03 | -5.80 | GSE24142_EARLY_THYMIC_PROGENITOR_VS_DN3_THYMOCYTE_ADULT_DN | MSigDB lists | GSE24142_EARLY_THYMIC_PROGENITOR_VS_DN3_THYMOCYTE_ADULT_DN | 188 | 43 | 17377 | 2626 |
UBE2D3,TCF12,DDX47,NDUFS1,CHD1L,MRPS26,AGFG1,CDC42SE2,SLC35B1,NCKAP1,AP3S1,TMEM165,PITHD1,PNO1,RPL11,C12orf10,RAB8A,C18orf32,MBD2,PHTF1,NOC2L,OSTC,CLTB,GTF2H2,SYTL3,EIF5A,RHOA,MRPL12,PTPRF,CHCHD3,PLD3,TIMM13,MRPL55,TPP2,ARNTL,CRCP,SLAIN1,FKBP5,TCOF1,GALNT10,PDLIM5,NGLY1,TMEM131 |
| 3.015e-03 | -5.80 | GSE41176_UNSTIM_VS_ANTI_IGM_STIM_TAK1_KO_BCELL_24H_UP | MSigDB lists | GSE41176_UNSTIM_VS_ANTI_IGM_STIM_TAK1_KO_BCELL_24H_UP | 188 | 43 | 17377 | 2626 |
GALK1,RAB14,GORASP1,WDR13,STARD7,MAN2B1,SND1,SAFB2,SDHA,BCAP31,RNF103,EBP,FKBP1A,SEC11A,DECR1,KLHL20,TIMELESS,KIF22,MDFIC,MRPL11,EIF5,TIPARP,KCNAB2,CPNE1,SNRNP200,MAN1B1,KIAA0930,OGFR,GOSR1,USP21,SLC50A1,ARHGAP15,EIF3K,MAN2A2,TSC1,FASTK,DCAF11,MLYCD,GPI,SMAD1,HIGD2A,CAPN1,AAAS |
| 3.015e-03 | -5.80 | GSE7852_THYMUS_VS_FAT_TREG_UP | MSigDB lists | GSE7852_THYMUS_VS_FAT_TREG_UP | 188 | 43 | 17377 | 2626 |
TP53RK,PPCS,PNISR,MPHOSPH8,RWDD1,MRPL39,TRMT6,GMCL1,PDCD7,ELMOD2,ANKRD39,EDC3,C2orf68,MRPL50,PSMA6,HDAC7,BDH1,BRD7,ATP6V0A2,BCL2,OSTC,MRPL11,SCYL3,N4BP2,SMC4,PHF10,RPRD1A,ZNF512,POLR2D,E2F3,DCUN1D5,GUF1,PDHX,CDC16,SEC23IP,TTLL4,DCK,LUC7L3,MRPL27,RNF38,NANP,COIL,PDF |
| 3.015e-03 | -5.80 | GSE10240_IL22_VS_IL22_AND_IL17_STIM_PRIMARY_BRONCHIAL_EPITHELIAL_CELLS_UP | MSigDB lists | GSE10240_IL22_VS_IL22_AND_IL17_STIM_PRIMARY_BRONCHIAL_EPITHELIAL_CELLS_UP | 188 | 43 | 17377 | 2626 |
SLC12A7,WSB2,HSPH1,PRKAB1,FEZ2,SCAMP3,ADD1,ZBTB37,AP3M2,CFLAR,KRI1,HERC3,CCNK,HOMER1,SNUPN,THADA,RINL,ARF5,PPME1,MEA1,NDUFA3,GCC1,RNF5,USP34,CSNK1G2,ZNF524,TIMP2,TSPYL4,SELPLG,COQ10B,TUFM,RFXANK,ESYT1,DAPK3,MBOAT1,GALNT10,AKNA,SMURF1,PDCD11,GLCCI1,NRBP1,C7orf26,ZC3HAV1 |
| 3.015e-03 | -5.80 | GSE6674_PL2_3_VS_ANTI_IGM_AND_CPG_STIM_BCELL_UP | MSigDB lists | GSE6674_PL2_3_VS_ANTI_IGM_AND_CPG_STIM_BCELL_UP | 188 | 43 | 17377 | 2626 |
ZNF207,DNMT3A,SCAMP3,SUCLG1,PPP1R15B,SNX15,DNAJB1,SPR,IL21R,POLR3K,ABHD16A,RPA2,ATIC,XRCC2,AXIN2,ATP6V0A2,FRMD8,HNRNPM,LYPLA2,AMPD2,TK1,AKT2,POLR2D,RRM2,SLBP,SSR2,CDC6,RTF1,IL12RB1,SRSF1,SLCO4A1,MID1IP1,CDCA4,CDKN2AIPNL,SYNCRIP,ZNF367,ACBD4,ANP32E,NANP,ARRB2,LTA4H,PSMC1,EYA2 |
| 3.015e-03 | -5.80 | GSE22886_CD4_TCELL_VS_BCELL_NAIVE_UP | MSigDB lists | GSE22886_CD4_TCELL_VS_BCELL_NAIVE_UP | 188 | 43 | 17377 | 2626 |
GLT8D1,MRPS15,KLHL21,XAB2,SRGN,MOGS,ARID5A,EPHX2,RSAD1,PA2G4,PSMD1,EXOSC7,CDC42,GRSF1,ZBTB22,KIF22,CDC25B,CITED2,ASB6,PACS2,TACC3,NIPAL3,DDX28,TNFAIP3,GUK1,PBXIP1,ITM2A,MAP7D1,SOX4,PRMT2,OPTN,ATP1A1,LTBP4,PRDX3,CHD3,CABIN1,FKBP5,DVL1,ARRB2,NRBP1,TOB1,RTN3,ADNP2 |
| 3.019e-03 | -5.80 | positive regulation of metaphase/anaphase transition of cell cycle | biological process | GO:1902101 | 8 | 5 | 17256 | 2622 |
RB1,ESPL1,NSMCE2,CDT1,CUL3 |
| 3.019e-03 | -5.80 | lysosomal lumen acidification | biological process | GO:0007042 | 8 | 5 | 17256 | 2622 |
ATP6V0C,CLN3,PPT1,CLN6,SNAPIN |
| 3.019e-03 | -5.80 | cellular response to insulin-like growth factor stimulus | biological process | GO:1990314 | 8 | 5 | 17256 | 2622 |
TGFB1,CCNA2,CREB1,PTEN,SLC25A33 |
| 3.019e-03 | -5.80 | positive regulation of mitotic sister chromatid separation | biological process | GO:1901970 | 8 | 5 | 17256 | 2622 |
RB1,ESPL1,NSMCE2,CDT1,CUL3 |
| 3.019e-03 | -5.80 | centrosome separation | biological process | GO:0051299 | 8 | 5 | 17256 | 2622 |
NUP62,KIF3B,CNTROB,NDE1,KIF11 |
| 3.019e-03 | -5.80 | positive regulation of mitotic metaphase/anaphase transition | biological process | GO:0045842 | 8 | 5 | 17256 | 2622 |
RB1,ESPL1,NSMCE2,CDT1,CUL3 |
| 3.021e-03 | -5.80 | GSE16385_UNTREATED_VS_12H_IFNG_TNF_TREATED_MACROPHAGE_DN | MSigDB lists | GSE16385_UNTREATED_VS_12H_IFNG_TNF_TREATED_MACROPHAGE_DN | 172 | 40 | 17377 | 2626 |
WSB2,TMED7,NOP2,FAM129A,ANK3,NIPA2,MAN2B1,SND1,BRIX1,SLC12A9,MEAF6,HOMER1,SMC3,RAD23B,MRPL21,ABI1,RPL22L1,TIMM8B,EXOSC6,MLEC,RNASEH2C,FAM118B,COQ10B,TLK1,PRKAR1B,SMU1,NFATC2,ADRB2,MCFD2,KIF11,HMGN2,RAD51C,ATP6V1D,SYNCRIP,SLC38A7,CORO1C,TSPAN5,TOB1,RAD51D,SNAPIN |
| 3.022e-03 | -5.80 | N-Glycan biosynthesis | KEGG pathways | ko00510 | 49 | 16 | 7161 | 1149 |
DPM1,MAN1B1,MOGS,B4GALT1,MAN1A1,ALG3,MAN2A2,RPN1,DDOST,STT3A,DAD1,FUT8,RPN2,B4GALT3,MGAT5,B4GALT2 |
| 3.022e-03 | -5.80 | N-Glycan biosynthesis | KEGG pathways | hsa00510 | 49 | 16 | 7161 | 1149 |
MAN2A2,ALG3,RPN1,DDOST,DPM1,STT3A,DAD1,FUT8,MAN1B1,MOGS,B4GALT1,RPN2,B4GALT3,MGAT5,B4GALT2,MAN1A1 |
| 3.031e-03 | -5.80 | UBE2V1 (ubiquitin conjugating enzyme E2 V1) | protein interactions | 7335 | 84 | 24 | 17029 | 2761 |
TRIM8,TXN,BIRC3,RAB7A,XIAP,UBE4B,POMP,ATP6V1B2,BIRC2,RHBDF2,HINT1,TTC9C,YWHAZ,TAGLN2,TRIM32,AHCYL1,RNF14,UBE2C,SMURF1,RNF5,SSSCA1,USP34,ATP6V1G1,LDHB |
| 3.031e-03 | -5.80 | ASS1 (argininosuccinate synthase 1) | protein interactions | 445 | 84 | 24 | 17029 | 2761 |
HSPH1,PDCD6IP,TXN,GNPDA1,TKT,NANS,PKM,SPR,APP,GIT2,PRDX1,USF1,TNFAIP8,ATG3,CTSA,KPNA2,TAGLN2,RUVBL2,TERF1,CAPN1,ANXA11,HTRA2,TERF2,LDHB |
| 3.035e-03 | -5.80 | catalytic activity, acting on a tRNA | molecular function | GO:0140101 | 123 | 31 | 17224 | 2647 |
RPP25,METTL1,KARS,LARS,HARS,MRPL39,TYW1,NSUN2,METTL2A,POLG2,TARS,FARSA,EPRS,GATC,IARS,DUS3L,DUS4L,QARS,POP7,TYW5,WDR4,FTSJ1,DUS2,IARS2,QRSL1,TRMT10B,DTD1,TSEN15,PDCL3,TYW1B,CARS2 |
| 3.039e-03 | -5.80 | Regulation of ornithine decarboxylase (ODC) | REACTOME pathways | R-HSA-350562 | 52 | 17 | 10287 | 1696 |
NQO1,PSMA8,PSMB7,PSMA1,ODC1,PSMB9,PSMD9,PSMB3,PSMC4,PSMD2,PSMA6,PSMD1,PSMD3,PSMD8,OAZ2,OAZ1,PSMC1 |
| 3.043e-03 | -5.79 | Physiological and Pathological Hypertrophy of the Heart | WikiPathways | WP1528 | 25 | 10 | 5312 | 837 |
CALM2,PPP3CA,RHOA,IL6ST,RAC1,PPP3CB,STAT3,MAPK14,MAPK1,MYEF2 |
| 3.046e-03 | -5.79 | KEGG_NEUROTROPHIN_SIGNALING_PATHWAY | MSigDB lists | KEGG_NEUROTROPHIN_SIGNALING_PATHWAY | 125 | 31 | 17377 | 2626 |
PDPK1,RHOA,NRAS,AKT2,RPS6KA1,RAF1,MAGED1,RAC1,KRAS,ARHGDIB,PSEN1,MAPK14,FOXO3,MAP2K2,MAPK3,CRKL,CALM2,RAP1A,SHC1,CDC42,CSK,PIK3R2,PRDM4,PTPN11,YWHAZ,BCL2,MAP3K5,MAPK1,YWHAH,HRAS,CAMK2G |
| 3.049e-03 | -5.79 | V$SP1_01 | MSigDB lists | V$SP1_01 | 226 | 50 | 17377 | 2626 |
TCF12,UBE2D3,DNMT3A,GGNBP2,ADAM10,GGA1,MAGED1,SLC2A1,UBE2Z,JMJD6,STMN1,BZW2,FBRS,HNRNPA2B1,KDM2A,KLF16,UTP18,LRRC8D,SLC44A1,BCL2,CITED2,FBXL19,NCOA2,SPSB3,CLPTM1,EIF5A,NRAS,ZNF512,PPP1R21,RDH10,ATXN1,PACS1,ARID1A,CADM1,KDM3A,C1orf122,HMGN2,MAGED2,MTMR3,VEZF1,SYNCRIP,GRIPAP1,CDCA7L,OAZ2,ACLY,ARAP1,RBBP4,NR2F2,FAF1,B4GALT2 |
| 3.054e-03 | -5.79 | WWE | prosite domains | PS50918 | 12 | 6 | 12060 | 1670 |
PARP12,TRIP12,HUWE1,TIPARP,ZC3HAV1,DTX4 |
| 3.060e-03 | -5.79 | GO_NEGATIVE_REGULATION_OF_INTRACELLULAR_SIGNAL_TRANSDUCTION | MSigDB lists | GO_NEGATIVE_REGULATION_OF_INTRACELLULAR_SIGNAL_TRANSDUCTION | 417 | 84 | 17377 | 2626 |
ASH1L,CYLD,TSC2,FOXM1,NF1,IVNS1ABP,UBR2,BCL2L1,DUSP22,LYN,PARK7,EPM2A,PRNP,CALM2,RRN3,MDM2,PIN1,SOCS6,SRI,NOC2L,PARL,GPD1L,HTRA2,CPNE1,PPIF,PGAP2,TIMP2,PBK,VDAC2,CUL3,EZR,MCL1,DNAJA1,OPTN,SOCS7,PPP2CA,STK38,ARNTL,STAT1,ITGB1,SOCS4,STK11,TRIM32,CLU,ARRB2,PDCD4,MIF,BCL2L12,HSPH1,PRKAA1,CIB1,AKT1S1,RGS2,PTPN2,FKBP1A,PTEN,HDAC7,ARHGEF2,BCL2,PIK3IP1,SOCS5,TNFAIP3,ZMYND11,GBA,RFFL,SYVN1,MEN1,PTTG1IP,PDE3B,MFN2,LEMD2,TMEM127,TSC1,MBIP,HGS,PDCD6,GPS2,CSK,DUSP3,NUP62,PKD2,IGBP1,HIPK3,FAF1 |
| 3.063e-03 | -5.79 | GO_POSITIVE_REGULATION_OF_MULTI_ORGANISM_PROCESS | MSigDB lists | GO_POSITIVE_REGULATION_OF_MULTI_ORGANISM_PROCESS | 151 | 36 | 17377 | 2626 |
MIF,PPIB,CTDP1,CHMP2A,POLR2K,TRIM11,YTHDC2,CIB1,SMARCA4,SIRT2,CHD1,GTF2F1,RAD23A,TFAP4,ZNF639,MDFIC,LRSAM1,PABPC1,CFL1,SRPK2,STAU1,POLR2I,POLR2L,POLR2G,RAB7A,PPIE,POLR2D,CHMP2B,ZP3,POLR2A,MAPK3,POLR2J,CHMP4B,VPS4A,DDB1,ZC3HAV1 |
| 3.066e-03 | -5.79 | PID_SMAD2_3NUCLEAR_PATHWAY | MSigDB lists | PID_SMAD2_3NUCLEAR_PATHWAY | 80 | 22 | 17377 | 2626 |
SP3,MAX,KAT2A,TCF3,CBFB,ITGB5,FOXO3,SMAD2,RBL1,E2F4,TFE3,TFDP1,DCP1A,NCOA1,CREB1,RBBP4,CDK2,ATF2,SMAD4,NCOA2,HDAC2,SAP30 |
| 3.066e-03 | -5.79 | Pyrimidine metabolism | KEGG pathways | hsa00240 | 104 | 28 | 7161 | 1149 |
POLA2,POLR2I,TK1,POLR2G,POLR2L,PRIM2,POLR2K,UCK2,POLR2D,RRM1,POLR3GL,UCK1,RRM2,DCTD,POLR3K,POLR2A,TWISTNB,PRIM1,POLE,POLR2J,DCK,DUT,NT5C3B,CTPS1,CANT1,UPRT,POLR1B,ZNRD1 |
| 3.066e-03 | -5.79 | Pyrimidine metabolism | KEGG pathways | ko00240 | 104 | 28 | 7161 | 1149 |
POLA2,TK1,POLR2I,POLR2G,POLR2L,PRIM2,POLR2K,POLR2D,UCK2,RRM1,POLR3GL,UCK1,RRM2,DCTD,POLR3K,POLR2A,TWISTNB,PRIM1,POLE,POLR2J,NT5C3B,DUT,DCK,CTPS1,CANT1,UPRT,POLR1B,ZNRD1 |
| 3.079e-03 | -5.78 | regulation of cell size | biological process | GO:0008361 | 166 | 39 | 17256 | 2622 |
SLC12A7,ADD1,RAC1,VAV2,WDTC1,PLXNA1,AKT1S1,SLC12A9,TWF2,RAB11A,CDK5,VAV1,RAB21,PTEN,MEGF8,DPYSL2,CLCN6,DNM2,ZFYVE27,CREB1,SLC12A2,MTPN,CYFIP1,IFRD1,CLCN3,LARS,RHOA,RB1CC1,EZR,LRRC8A,ANAPC2,MACF1,CLNS1A,TSC1,GOLGA4,E2F4,LIMK1,LAMTOR4,RUFY3 |
| 3.084e-03 | -5.78 | Senescence and Autophagy in Cancer | WikiPathways | WP615 | 106 | 28 | 5312 | 837 |
TGFB1,CREG1,RB1CC1,RAF1,AKT1S1,MAP1LC3B,BECN1,MAPK14,SH3GLB1,IRF5,RB1,MDM2,PCNA,PTEN,ATG3,IL6ST,E2F1,CDKN1B,ATG13,BCL2,RNASEL,CDC25B,MAPK1,HRAS,SMAD4,IFI16,CDKN2A,MLST8 |
| 3.086e-03 | -5.78 | citrate metabolic process | biological process | GO:0006101 | 34 | 12 | 17256 | 2622 |
SDHB,SUCLG1,MDH2,IDH3A,ACLY,CS,SUCLG2,DHTKD1,MDH1,OGDH,IDH3B,SDHA |
| 3.097e-03 | -5.78 | KEGG_CITRATE_CYCLE_TCA_CYCLE | MSigDB lists | KEGG_CITRATE_CYCLE_TCA_CYCLE | 30 | 11 | 17377 | 2626 |
SDHB,SUCLG1,MDH2,IDH3A,ACLY,CS,SUCLG2,MDH1,OGDH,IDH3B,SDHA |
| 3.097e-03 | -5.78 | ZHAN_MULTIPLE_MYELOMA_SUBGROUPS | MSigDB lists | ZHAN_MULTIPLE_MYELOMA_SUBGROUPS | 30 | 11 | 17377 | 2626 |
FKBP1A,FNTA,EWSR1,UGP2,PRKDC,MSH2,CDC6,SNRPD3,CHAF1A,TMEM131,PRIM1 |
| 3.097e-03 | -5.78 | GO_MULTIVESICULAR_BODY_ORGANIZATION | MSigDB lists | GO_MULTIVESICULAR_BODY_ORGANIZATION | 30 | 11 | 17377 | 2626 |
CHMP2A,HGS,PDCD6IP,CHMP4A,CHMP4B,VPS4A,CHMP2B,CHMP7,RAB11A,VPS25,STAM |
| 3.098e-03 | -5.78 | ATAACCT,MIR-154 | MSigDB lists | ATAACCT,MIR-154 | 61 | 18 | 17377 | 2626 |
UBE2D3,TCF12,CIC,KAT7,PLAGL2,BRCA1,RAB5B,KPNA1,PCNA,HNRNPR,OSBPL8,MAP4,OGT,RNF19A,HDHD2,CAMK2G,FGFR1OP2,SOCS5 |
| 3.101e-03 | -5.78 | TCEA2 (transcription elongation factor A2) | protein interactions | 6919 | 66 | 20 | 17029 | 2761 |
MYH9,BRCA1,AKT1S1,EAF2,ANLN,MCM2,CDK11B,APP,DNAJB9,LMNA,RPA1,CAND1,MAGED2,GOLGA2,POLR2J,EIF4A3,GRIPAP1,DHX16,TCEA1,CENPT |
| 3.102e-03 | -5.78 | GO_REGULATION_OF_TRANSLATIONAL_ELONGATION | MSigDB lists | GO_REGULATION_OF_TRANSLATIONAL_ELONGATION | 22 | 9 | 17377 | 2626 |
EIF5A,LARS,GATC,IARS,EIF4A3,IARS2,DTD1,RPS9,CPEB2 |
| 3.105e-03 | -5.77 | negative regulation of cellular protein metabolic process | biological process | GO:0032269 | 1071 | 195 | 17256 | 2622 |
ZBED3,FGFR1OP,TSC2,NF1,FAM129A,PPP1R15B,XIAP,ENSA,CSNK2A1,YTHDF3,SIRT2,CCNB1,PPP1R16B,RBM4,BIRC2,RIC1,PARK7,PRNP,CALM2,CDK5,CDKN2C,EIF4A3,METTL14,PIK3R2,NOC2L,CRY2,DNMT1,SENP1,RYBP,PLK1,BAK1,NCK1,PBK,GMFB,EZR,LRP5,BRCA1,SOX4,EIF3A,HHEX,EIF4ENIF1,LIMK1,PRDX5,SOCS4,OGT,DVL1,ROCK1,CLN3,ARRB2,HDAC2,PDCD4,SVIP,HSPH1,PPP1R2,GMFG,UBXN1,PRKAA1,CIB1,TIA1,EIF2AK4,RGS2,PSEN1,METTL3,VPS25,CNOT3,CFLAR,CD59,TFAP4,FKBP1A,RB1,MEX3C,FBXO7,DAPK1,ARL6IP1,MVP,GNAI2,SOCS5,ZMYND11,OXR1,GTPBP4,GBA,EIF2AK1,FXR1,KDM3A,DAPK3,ISG15,MASTL,TSC1,MBIP,EPRS,SYNCRIP,DUSP3,CSK,QARS,SIAH2,NUP62,CABIN1,TOB1,RNF139,CDKN2A,USP7,PPP1R37,GGNBP2,ASH1L,FOXM1,RPS6KA1,RAF1,CAST,PTTG1,LYN,DUSP22,APP,PAIP2,RPL11,TERF2IP,APLP2,MDM2,TNFAIP8,PPME1,UCHL5,PIN1,SOCS6,CDKN1B,TARDBP,GPD1L,STRAP,CTDSP2,PDCL3,CHP1,SNX25,TIMP2,BIRC3,BTG2,CIRBP,DNAJA1,SOCS7,PPP2CA,DNAJC10,IDE,HNRNPR,HIPK2,STK38,CORO1C,GADD45B,PPP5C,SMAD4,PARD3,MIF,BCL2L12,UNK,TRIP12,MECP2,AGO2,AKT1S1,HMG20A,MAD2L2,FBXO5,PTPN2,PTEN,PPP1R8,DUS2,H2AFY,CNOT6L,STAT3,PDPK1,TGFB1,SAMD4B,PPP1R9B,TNFAIP3,PRKDC,ILF3,PRKAR1B,RFFL,MEN1,PICALM,HSPA1B,CNOT9,LEMD2,SH3BP5,UPF1,PLAA,BIRC5,GPS2,PRDX3,PML,GLG1,KHSRP,PPP1R11,NR2F2,PARP10,IGBP1,CPEB2,PURA,HIPK3,IFI16 |
| 3.105e-03 | -5.77 | TACC3 (transforming acidic coiled-coil containing protein 3) | protein interactions | 10460 | 75 | 22 | 17029 | 2761 |
RAB14,KAT2A,RAE1,SLBP,KIF11,XPR1,SRXN1,RAD23A,ZER1,OIP5,VASP,HSPBP1,CDC27,SNAP29,MBD2,METTL14,RAD23B,ORC3,RNF135,AHCYL1,SSSCA1,PDF |
| 3.105e-03 | -5.77 | DKKL1 (dickkopf like acrosomal protein 1) | protein interactions | 27120 | 75 | 22 | 17029 | 2761 |
INTS2,CELSR2,OAF,AMD1,TUFM,LRP5,GALNT7,KIAA1147,XPR1,RAD51C,APLP2,NUCB1,POLE,TBL3,FJX1,XRCC2,CBWD1,LTN1,CANT1,INTS12,GPD1L,RAD51D |
| 3.116e-03 | -5.77 | vesicle membrane | cellular component | GO:0012506 | 778 | 143 | 18223 | 2701 |
TMED7,RAB14,COPA,ADAM10,ZDHHC8,SNX15,TAP1,AP3M2,TGOLN2,SEC16A,SYNRG,CMTM6,RAB8A,RAP1A,AP3S2,DBNDD1,RAB35,RAB4A,SRI,AP1M1,DNM2,AP2B1,KCNAB2,USO1,NRAS,NCK1,CYSTM1,SLC17A5,MCFD2,RAB5B,RAB22A,NECAP2,WAS,AGPAT2,TMED10,RPS27A,ATP6V0C,C2CD5,ATP6V0E1,SVIP,DNAJC5,AGTRAP,HLA-E,RAB23,LAMTOR3,B4GALT1,TMED3,RAB6A,PSEN1,COPG2,COPB2,TMEM179B,CD59,SNX18,ZNRF2,ATP6V0A2,PIKFYVE,LPCAT1,ATP6V0D1,TMED2,KDELR1,VOPP1,ADRB2,APPL1,PI4K2A,SEC31A,SCARB2,SNAP23,YWHAZ,UNC13C,EXOC3,RHOG,ANKRD27,ABCA3,RAB11B,DYNLL1,COPE,RAC1,VTI1A,BCL2L1,AP1B1,CPNE3,RAB21,ATP6V0B,APLP2,MDM2,ATP2A2,SAR1A,BRI3,TAP2,CYB5R1,CORO1A,LMAN1,CLTB,TMBIM1,CPNE1,ENPP4,CLCN3,RAB7A,SLC26A6,ATP6V0A1,RAB1A,PEF1,ALDH3B1,CHMP4A,DDOST,SURF4,RAB24,SCAP,AP1S1,SCARB1,AP2S1,MANBA,SCYL1,TMX3,AP3S1,RAB11A,MFSD10,HLA-A,FZD6,TFRC,CLIC4,SEC24C,ZDHHC13,CAMK2G,RHOA,MLEC,DENND4C,KCNQ1,PICALM,HLA-B,RAB18,PDCD6,ATP6V1D,SEC23IP,MAGT1,WNT5B,SNAP29,PGRMC1,PKD2,PSAP,YWHAH,SNAPIN |
| 3.125e-03 | -5.77 | negative regulation of phosphate metabolic process | biological process | GO:0045936 | 612 | 118 | 17256 | 2622 |
ZBED3,FGFR1OP,PPP1R37,ASH1L,GGNBP2,TSC2,FOXM1,NF1,DYNLL1,FAM129A,PPP1R15B,ENSA,SIRT2,CCNB1,PPP1R16B,LYN,DUSP22,PARK7,PRNP,TERF2IP,CALM2,CDKN2C,PIN1,PPME1,PIK3R2,SOCS6,PPP1R12C,CDKN1B,CRY2,TARDBP,GPD1L,STRAP,CTDSP2,CHP1,PLK1,ANKLE2,SNX25,BAK1,PPIF,NCK1,PBK,GMFB,EZR,LRP5,PKMYT1,DNAJA1,EIF3A,PLEKHF2,SOCS7,PPP2CA,HHEX,DNAJC10,PPP2R5A,CORO1C,STK38,GADD45B,SOCS4,DVL1,ROCK1,PPP5C,ARRB2,SMAD4,PARD3,PDCD4,HSPH1,ZCCHC9,PPP1R2,PPP1R12A,GMFG,CIB1,AKT1S1,RGS2,PSEN1,VPS25,PTPN2,FKBP1A,TFAP4,RB1,TIGAR,PTEN,PPP1R8,FBXO7,DUS2,H2AFY,PIK3IP1,MVP,GNAI2,LPCAT1,STAT3,SOCS5,PDPK1,TGFB1,PPP1R9B,RHOA,TNFAIP3,ZMYND11,PRKDC,PRKAR1B,GBA,WDR81,MEN1,MASTL,LEMD2,SH3BP5,MBIP,GPS2,DUSP3,CSK,PRDX3,QARS,PPP1R11,NUP62,CABIN1,NR2F2,IGBP1,HIPK3,CDKN2A,EGLN1 |
| 3.130e-03 | -5.77 | GSE360_L_DONOVANI_VS_L_MAJOR_DC_DN | MSigDB lists | GSE360_L_DONOVANI_VS_L_MAJOR_DC_DN | 183 | 42 | 17377 | 2626 |
POU3F2,PLXNC1,UGP2,GADD45G,SLC25A12,KLC1,CHKB,GNB2,METTL3,LMNA,HLA-A,CNOT3,LRRC14,CRAT,BCL2,SLC38A10,GPD1L,UBE2M,CTDSP2,CDC5L,CLCN3,RB1CC1,GALC,SREK1,CDC6,LY6E,KLF6,SOCS7,DPYSL3,SLC19A1,ALDH3B1,BRWD1,SEC61A1,CERS6,GPS2,HPS5,PSMD8,SSNA1,ZNF45,USF2,ARRB2,COIL |
| 3.130e-03 | -5.77 | GSE23308_WT_VS_MINERALCORTICOID_REC_KO_MACROPHAGE_CORTICOSTERONE_TREATED_UP | MSigDB lists | GSE23308_WT_VS_MINERALCORTICOID_REC_KO_MACROPHAGE_CORTICOSTERONE_TREATED_UP | 183 | 42 | 17377 | 2626 |
CYTIP,NDUFV2,RECQL,ZCCHC8,IVNS1ABP,CHD1L,CERK,KLF13,GTF3A,C12orf10,DECR1,ADCY9,TMEM8A,ERI3,NDUFA3,RPRD1B,CARM1,EBAG9,NTPCR,EID1,LACTB,DNAJC9,GLO1,BOLA1,MPG,HAGH,RFC2,STK17B,RPA1,ZNF282,ATP6V1D,HSPBP1,TOMM6,NDUFA11,DNAJC17,ZFP90,ACADM,MBD6,PREPL,SLC25A39,ATMIN,NUDT3 |
| 3.130e-03 | -5.77 | GSE29618_MONOCYTE_VS_PDC_DN | MSigDB lists | GSE29618_MONOCYTE_VS_PDC_DN | 183 | 42 | 17377 | 2626 |
PTMS,PPIB,TCF3,MAGED1,SLC2A1,SMC6,FKBP2,GGA2,ETS1,PPP1R16B,STMN1,APP,PAIP1,KIF5B,IRF4,SNRNP25,RIMS3,RRBP1,SCYL3,HMGN1,SEC61B,MLEC,BTAF1,LRBA,GNG7,MYBL2,MEF2D,SOX4,CYFIP2,ODC1,RPSA,PCM1,HINT1,TMED10,GOLGA8A,LUC7L3,DCK,OGT,ST3GAL2,USP11,NGLY1,LRP8 |
| 3.130e-03 | -5.77 | GSE27786_BCELL_VS_NKCELL_UP | MSigDB lists | GSE27786_BCELL_VS_NKCELL_UP | 183 | 42 | 17377 | 2626 |
TOMM20,PPCS,CBLL1,CTCF,JMJD6,GMCL1,CNTROB,EIF1B,GGPS1,PARK7,SAC3D1,NDUFS4,FASTKD3,C1GALT1,IARS,RABGAP1L,AKAP8,CNPY4,DCP1A,CABLES2,TIMM50,USP34,SNX25,CSNK1G2,RPL35,POLR2D,ZNF574,TBRG4,DNAJC9,ELK1,MEN1,TTC33,PHF6,CLNS1A,BTBD1,SRSF1,RDH11,ACAT1,ZBTB11,GEN1,IPO4,S100PBP |
| 3.130e-03 | -5.77 | GSE13522_WT_VS_IFNAR_KO_SKIN_UP | MSigDB lists | GSE13522_WT_VS_IFNAR_KO_SKIN_UP | 183 | 42 | 17377 | 2626 |
CKLF,GMFG,SESTD1,ANKH,KIF23,SIKE1,SNRPD3,SUPT7L,OAT,SLC20A1,ZADH2,APP,HDDC2,SEC11A,RAD23B,OSTF1,NAP1L4,PDIA6,WDR41,VOPP1,METTL1,CREG1,EMB,BTG2,TMEM216,LRRC1,TANC1,CHCHD3,RAD51C,ZNF180,ATP6V1D,MID1IP1,HSPB11,APPL2,ACAT1,PITPNA,DTD1,SNRPG,WDR76,SMAD1,GPATCH4,SSRP1 |
| 3.130e-03 | -5.77 | GSE14908_RESTING_VS_HDM_STIM_CD4_TCELL_ATOPIC_PATIENT_UP | MSigDB lists | GSE14908_RESTING_VS_HDM_STIM_CD4_TCELL_ATOPIC_PATIENT_UP | 183 | 42 | 17377 | 2626 |
CCNC,HIVEP3,RPS2,H2AFZ,NUP188,UFC1,GTF3A,HMGN3,TAF6L,CHAC2,WDR5,MFSD10,FKBP1A,RNF121,SLC31A1,DECR1,FBXL6,PELO,FEM1B,KIFAP3,CYB5R1,NAA35,ALDH9A1,PPAN,PSMA1,SLC25A22,BMS1,THNSL1,UTP3,PKMYT1,GALK2,MBD3,TARS,MASTL,KEAP1,ATF6,TMEM101,TCOF1,CDK2,ZMAT3,DDB1,SSRP1 |
| 3.146e-03 | -5.76 | V$MAZR_01 | MSigDB lists | V$MAZR_01 | 210 | 47 | 17377 | 2626 |
POU3F2,TRIM41,DNMT3A,TRERF1,TRIP10,PHF23,RAB11B,EYA1,ENSA,SLC4A2,NOTCH2,FKBP2,MIEN1,GNB2,WDR48,FBRS,ZER1,GART,VASP,UTP18,CLCN6,TNPO2,ATF2,FBXL19,NCOA2,CAMK2G,LUC7L2,EIF5A,STAU1,PRRC2A,BAZ2A,WDR81,UBE4B,CBFB,MBD3,MAGED2,PTPRF,VEZF1,CACNB1,CDC27,RBL1,HNRNPR,CORO1C,MBD6,ROCK1,RTN3,ATXN7L2 |
| 3.149e-03 | -5.76 | FAM9B (family with sequence similarity 9 member B) | protein interactions | 171483 | 122 | 32 | 17029 | 2761 |
UBE2E2,MRPL9,EBNA1BP2,LYRM2,CMTM6,LMNA,RBM17,CSDE1,FASTKD3,C12orf10,GSTK1,RBM23,AP1M1,MOB1A,ASB6,ZCCHC10,PPP1R18,C16orf72,GOPC,TUFM,ELOA,TBRG4,PRPF3,CDC23,EIF3G,ECH1,SNAP29,MFAP1,CDCA7L,NDE1,XRCC4,BYSL |
| 3.153e-03 | -5.76 | APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint | REACTOME pathways | R-HSA-179419 | 74 | 22 | 10287 | 1696 |
PSMA8,PSMB7,PSMA1,ANAPC2,CDC23,PSMD9,PSMB9,PSMB3,PSMC4,PSMD2,PSMA6,CCNA2,CDC16,PSMD1,CDC27,RPS27A,PSMD8,PSMD3,ANAPC7,UBE2C,PSMC1,ANAPC4 |
| 3.158e-03 | -5.76 | GO_REGULATION_OF_PROTEIN_COMPLEX_ASSEMBLY | MSigDB lists | GO_REGULATION_OF_PROTEIN_COMPLEX_ASSEMBLY | 349 | 72 | 17377 | 2626 |
ANKRD27,CHMP2A,PDCD6IP,ADD1,RAF1,RAC1,CHD1L,ACTR3,SIRT2,TWF2,STMN1,BIRC2,PARK7,RRN3,CDC42,RALB,KIF14,CDKN1B,FNIP2,CORO1A,MTPN,MLST8,PLK1,ERCC1,PSRC1,RBX1,NCK1,TUBGCP5,GMFB,VDAC2,WIPF1,CHMP2B,PEX5,IDE,WAS,CHMP4B,NCLN,PIEZO1,CLU,PSMC1,SVIP,MAPRE1,HJURP,GMFG,ARFIP2,NCKAP1,ARF1,RGS2,TUBGCP2,JMY,RPA2,VASP,ARPC5,XPA,CAPZA1,PTPN11,CREB1,GTF2H2,SPTAN1,TGFB1,CYFIP1,BCLAF1,CAPZA2,ARPC1A,SH3GLB1,CAND1,RPA1,PSMC4,FAS,TERF1,DDB1,FAF1 |
| 3.165e-03 | -5.76 | SUMO transferase activity | molecular function | GO:0019789 | 18 | 8 | 17224 | 2647 |
KIAA1586,TOPORS,MDM2,UBE2I,HDAC7,NSMCE2,CBX4,PIAS2 |
| 3.166e-03 | -5.76 | REACTOME_ENDOSOMAL_SORTING_COMPLEX_REQUIRED_FOR_TRANSPORT_ESCRT | MSigDB lists | REACTOME_ENDOSOMAL_SORTING_COMPLEX_REQUIRED_FOR_TRANSPORT_ESCRT | 26 | 10 | 17377 | 2626 |
CHMP2A,HGS,CHMP4A,RPS27A,CHMP4B,VPS4A,CHMP2B,CHMP7,VPS25,STAM |
| 3.166e-03 | -5.76 | GO_REGULATION_OF_MRNA_3_END_PROCESSING | MSigDB lists | GO_REGULATION_OF_MRNA_3_END_PROCESSING | 26 | 10 | 17377 | 2626 |
PAF1,POLR2G,BTG2,CTR9,CCNB1,AHCYL1,CDC73,PABPC1,TOB1,PAPOLA |
| 3.166e-03 | -5.76 | NIKOLSKY_BREAST_CANCER_5P15_AMPLICON | MSigDB lists | NIKOLSKY_BREAST_CANCER_5P15_AMPLICON | 26 | 10 | 17377 | 2626 |
SLC12A7,EXOC3,PDCD6,PLEKHG4B,NKD2,LPCAT1,BRD9,SDHA,CCDC127,LRRC14B |
| 3.166e-03 | -5.76 | PID_P38_MKK3_6PATHWAY | MSigDB lists | PID_P38_MKK3_6PATHWAY | 26 | 10 | 17377 | 2626 |
MAP3K4,TXN,TAB2,GADD45B,TAOK1,RAC1,GADD45G,CCM2,MAP3K5,MAPK14 |
| 3.166e-03 | -5.76 | GNF2_LYN | MSigDB lists | GNF2_LYN | 26 | 10 | 17377 | 2626 |
WAS,SNX2,STAT6,DAZAP2,LTA4H,LYN,CNPY3,SERP1,GIT2,CMTM6 |
| 3.166e-03 | -5.76 | GO_MRNA_SPLICE_SITE_SELECTION | MSigDB lists | GO_MRNA_SPLICE_SITE_SELECTION | 26 | 10 | 17377 | 2626 |
YTHDC1,LUC7L3,SRSF6,SRSF5,PRPF39,LUC7L,SF3A2,LUC7L2,SRSF10,SRSF1 |
| 3.170e-03 | -5.75 | human chr2p13.1 | chromosome location | human chr2p13.1 | 41 | 11 | 26185 | 2809 |
TET3,BOLA3,MTHFD2,MOGS,DUSP11,WBP1,PCGF1,MOB1A,HTRA2,RTKN,DCTN1 |
| 3.172e-03 | -5.75 | GO_OXIDOREDUCTASE_ACTIVITY_ACTING_ON_NAD_P_H | MSigDB lists | GO_OXIDOREDUCTASE_ACTIVITY_ACTING_ON_NAD_P_H | 90 | 24 | 17377 | 2626 |
NDUFA5,COX15,NDUFV2,NDUFS1,NDUFB6,NQO1,NDUFAF2,NQO2,NDUFA4,NDUFA7,NDUFB1,NDUFS7,NDUFS4,DECR1,NDUFV1,NDUFA2,PRDX3,NDUFB4,CYB5RL,NDUFB9,NDUFS8,NDUFS5,CYB5R1,NDUFA3 |
| 3.179e-03 | -5.75 | trans-Golgi network | cellular component | GO:0005802 | 203 | 45 | 18223 | 2701 |
RAB14,CORO7,GOLPH3L,SYS1,SCOC,RAC1,VTI1A,ARFIP2,TGOLN2,RAB6A,AP1B1,GGA2,BECN1,TMEM165,RAB11A,RIC1,APP,RAB21,RAB8A,KLHL20,AP1M1,DNM2,AP2B1,CLTB,GCC2,RHOBTB3,TRAPPC9,ATG9A,LAP3,ATP2C1,COG1,AP4E1,STX16,OPTN,PI4K2A,NUCB1,GOLGA4,MYO18A,ARAP1,AP1S1,SMPD4,PLOD3,CLN3,ECPAS,CHID1 |
| 3.180e-03 | -5.75 | beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity | molecular function | GO:0003831 | 8 | 5 | 17224 | 2647 |
B4GALT1,B4GALT4,B4GALT3,B4GALT5,B4GALT2 |
| 3.180e-03 | -5.75 | P-P-bond-hydrolysis-driven protein transmembrane transporter activity | molecular function | GO:0015450 | 8 | 5 | 17224 | 2647 |
SEC61B,TOMM20,SEC61G,TIMM23,TIMM17A |
| 3.180e-03 | -5.75 | recombinase activity | molecular function | GO:0000150 | 8 | 5 | 17224 | 2647 |
RAD51C,XRCC3,RBPJ,RAD51D,XRCC2 |
| 3.184e-03 | -5.75 | BILD_E2F3_ONCOGENIC_SIGNATURE | MSigDB lists | BILD_E2F3_ONCOGENIC_SIGNATURE | 221 | 49 | 17377 | 2626 |
TMEM106C,NAT9,HECA,SRSF6,ABCC10,ANKH,TMEM97,C5orf30,SLC25A12,ABCB10,PXMP2,ZNF275,SAC3D1,RAVER2,DTL,CDKN2C,FGFR3,NFATC3,PCNA,CCP110,SYNM,RPL17,PIN1,AKR1B1,PLCL2,FAM171A1,UBE2QL1,GINS1,TSHZ1,PHF10,NASP,TNFAIP3,DNAJC9,PFKFB3,NUP155,RPA1,GNAS,FBXO21,ATAD2,POLE,RBM25,DCK,ZNF367,TFDP1,MBOAT1,WIPI2,TSPAN5,NIPA1,CDKN2A |
| 3.192e-03 | -5.75 | GGTGTGT,MIR-329 | MSigDB lists | GGTGTGT,MIR-329 | 105 | 27 | 17377 | 2626 |
GGA1,SUGP2,DLGAP4,ALKBH5,OLA1,ATXN1,CADM1,MARK2,CCDC28A,KRIT1,DPYSL3,SUGP1,SMAD2,AHNAK,IL6ST,SRSF4,DAPK1,RNF38,TARDBP,CNOT6,CLDND1,ERI3,H3F3A,SLC22A23,CLTB,CSNK1G3,PRPF4B |
| 3.195e-03 | -5.75 | TAKAO_RESPONSE_TO_UVB_RADIATION_DN | MSigDB lists | TAKAO_RESPONSE_TO_UVB_RADIATION_DN | 95 | 25 | 17377 | 2626 |
TOMM20,NUP188,TNFAIP3,DPM1,PHB2,CAST,GMFB,USP10,MCL1,DNAJB1,OGDH,DAZAP2,RGS2,CBFB,EIF4H,RAB11A,CCT8,MKNK1,ATIC,RAD23B,PITPNA,SRSF3,RRS1,IFI16,HNRNPM |
| 3.198e-03 | -5.75 | G2 Phase | REACTOME pathways | R-HSA-68911 | 5 | 4 | 10287 | 1696 |
CCNA2,CDK2,E2F1,E2F3 |
| 3.205e-03 | -5.74 | DAZARD_RESPONSE_TO_UV_NHEK_UP | MSigDB lists | DAZARD_RESPONSE_TO_UV_NHEK_UP | 232 | 51 | 17377 | 2626 |
IER2,RPS2,TXN,SEC61G,DYNLL1,HEXB,CTCF,EIF1B,MAP1LC3B,RAP1A,GATC,POP7,BCL2,CITED2,MVP,CLTB,UBE2M,DCTN1,PPIF,TGFB1,ERCC1,TK1,TNFAIP3,GUK1,CSRP1,TSTA3,GBA,RPL38,LY6E,TXNL4A,ODC1,API5,STK17B,EIF3G,RPSA,NEU1,RPL37,NUCB1,BRD2,GPS2,ZNF330,PSMD8,TFE3,STAT6,GADD45B,ERGIC3,H2AFX,GPI,PDLIM5,HRAS,TOB1 |
| 3.206e-03 | -5.74 | Translesion synthesis by POLK | REACTOME pathways | R-HSA-5655862 | 17 | 8 | 10287 | 1696 |
RPA2,PCNA,RFC3,RFC2,POLK,RPS27A,MAD2L2,RPA1 |
| 3.206e-03 | -5.74 | RHO GTPases Activate ROCKs | REACTOME pathways | R-HSA-5627117 | 17 | 8 | 10287 | 1696 |
MYH9,ROCK1,RHOA,PPP1R12A,LIMK1,MYL12B,RHOC,RHOB |
| 3.209e-03 | -5.74 | PIR (pirin) | protein interactions | 8544 | 53 | 17 | 17029 | 2761 |
MIF,PDCD6IP,GNPDA1,TKT,TIA1,NANS,STAM,PARK7,CLNS1A,SRXN1,C2orf68,PPP2CA,KLHL20,SRI,HTRA2,CFL1,FUBP1 |
| 3.209e-03 | -5.74 | PRPS1 (phosphoribosyl pyrophosphate synthetase 1) | protein interactions | 5631 | 53 | 17 | 17029 | 2761 |
RPAP3,TP53RK,CXXC1,GORASP2,PRPSAP1,EML4,NMT2,GTF2F1,BRMS1,FARSA,PRPS2,NDUFB9,TOP1MT,SMURF1,NMD3,POC5,PRPF19 |
| 3.209e-03 | -5.74 | SPEN (spen family transcriptional repressor) | protein interactions | 23013 | 53 | 17 | 17029 | 2761 |
CCNC,NCOR2,UBE2E2,MTA2,NUP54,ATXN1,BCLAF1,NOTCH2,MBD3,SCYL2,PIP4K2A,FERMT3,PRDX3,RBPJ,RBBP4,HDAC2,SRPK2 |
| 3.209e-03 | -5.74 | CORO1A (coronin 1A) | protein interactions | 11151 | 53 | 17 | 17029 | 2761 |
YTHDC1,TRAF7,GOLGA2,DDX24,RABGAP1L,POC1A,CORO1C,ACTR3,MRPL12,COX4I1,ACTB,BICD2,FAM208A,STAT3,POT1,GIT2,SMARCD1 |
| 3.209e-03 | -5.74 | Ddb1 (damage specific DNA binding protein 1) | protein interactions | 13194 | 53 | 17 | 17029 | 2761 |
DCAF6,RBX1,DCAF15,DCAF8,WDTC1,TOR1AIP2,PRPF18,DTL,DDA1,DCAF11,TRA2B,COPS7B,KPNA2,COPS6,ZC3H3,DDB1,NUDC |
| 3.216e-03 | -5.74 | GSE7548_NAIVE_VS_DAY7_PCC_IMMUNIZATION_CD4_TCELL_DN | MSigDB lists | GSE7548_NAIVE_VS_DAY7_PCC_IMMUNIZATION_CD4_TCELL_DN | 194 | 44 | 17377 | 2626 |
KARS,IER2,PRKAB1,TAP1,ARID5A,FLOT1,TIA1,LYN,EXT2,RBM4,BIRC2,TERF2IP,GART,SP100,RALB,RABGAP1L,SRSF4,NUP153,CLDND1,RP2,MVP,BAK1,SHOC2,TRAFD1,NASP,KIAA0040,DNAJA1,OGFR,KLF6,STK17B,DHX15,ISG15,FAS,PAF1,TRIM26,ETS2,PML,RBMS1,ATF6,RGL1,H3F3A,ZC3HAV1,IFI16,PFKP |
| 3.216e-03 | -5.74 | GSE3039_ALPHAALPHA_CD8_TCELL_VS_B1_BCELL_UP | MSigDB lists | GSE3039_ALPHAALPHA_CD8_TCELL_VS_B1_BCELL_UP | 194 | 44 | 17377 | 2626 |
RAB14,FEZ2,UFC1,RAC1,SLC2A1,MCCC1,SMC6,GLUD1,SIRT2,GFM2,PIP4K2A,RGS1,RNF103,TMCC3,GNS,CTSS,IL6ST,RIMS3,BDH1,DAPK1,NSFL1C,CPSF4,MVP,SOCS5,ELOVL5,ANKRD37,TSPYL4,POLK,PPP1R21,HEBP2,GALK2,GALNT7,VKORC1,ARSK,API5,SERP1,LSG1,MAGT1,ACOX1,CORO1C,ACLY,CTSA,RGL1,ZMAT3 |
| 3.216e-03 | -5.74 | GSE3039_NKT_CELL_VS_B2_BCELL_UP | MSigDB lists | GSE3039_NKT_CELL_VS_B2_BCELL_UP | 194 | 44 | 17377 | 2626 |
CCDC93,PPCS,CYLD,ZNF445,CHD1L,HNRNPUL2,TATDN3,TIA1,LANCL1,B4GALT4,APH1B,PARN,PIP4K2A,USP5,MAN1A1,ZER1,ADD3,NUP210,KLHL20,RIMS3,DAPK1,AP1M1,PIKFYVE,LDLRAD3,LPCAT1,ARL5A,GM2A,POU2AF1,MLEC,TACC1,RDH10,TUFM,HEBP2,EMP3,VKORC1,API5,CAT,PDLIM1,HIPK2,ANP32E,FAM126A,TFDP2,ESPL1,SSRP1 |
| 3.217e-03 | -5.74 | human chr9p21.1 | chromosome location | human chr9p21.1 | 15 | 6 | 26185 | 2809 |
B4GALT1,DDX58,TOPORS,DNAJA1,NDUFB6,SMU1 |
| 3.223e-03 | -5.74 | mitotic recombination | biological process | GO:0006312 | 22 | 9 | 17256 | 2622 |
RAD51C,ERCC1,NSMCE2,XRCC2,SMC6,XRCC3,GEN1,RAD51D,RAD54B |
| 3.223e-03 | -5.74 | regulation of sister chromatid cohesion | biological process | GO:0007063 | 22 | 9 | 17256 | 2622 |
RB1,NSMCE2,CDCA5,AXIN2,CTCF,H2AFY,SLF1,ESPL1,SLF2 |
| 3.223e-03 | -5.74 | maintenance of protein location in nucleus | biological process | GO:0051457 | 22 | 9 | 17256 | 2622 |
CDK5,TXN,SP100,PML,RANGAP1,TOPORS,SUPT7L,PARK7,MORC3 |
| 3.223e-03 | -5.74 | endoplasmic reticulum calcium ion homeostasis | biological process | GO:0032469 | 22 | 9 | 17256 | 2622 |
BAK1,BCL2,ATP2A2,THADA,PSEN1,BCAP31,APP,KCTD17,PML |
| 3.223e-03 | -5.74 | centriole assembly | biological process | GO:0098534 | 22 | 9 | 17256 | 2622 |
CCP110,CENPJ,E2F4,NUP62,CEP63,CNTROB,WDR62,SASS6,CDK2 |
| 3.228e-03 | -5.74 | POP1 (POP1 homolog, ribonuclease P/MRP subunit) | protein interactions | 10940 | 89 | 25 | 17029 | 2761 |
RPP25,NIFK,STRIP1,RPL8,CUL3,GTPBP4,CUL1,CSNK2A1,EBNA1BP2,KIF2C,RBM4,CAND1,UPF1,DGCR8,RBM34,PPM1G,POP7,RBPJ,FBL,SNRNP70,ZC3H3,IFI16,GPATCH4,DCTN1,NIPSNAP1 |
| 3.228e-03 | -5.74 | SEPT7 (septin 7) | protein interactions | 989 | 89 | 25 | 17029 | 2761 |
SARNP,SEPT9,MRPL12,SEPT8,MYH9,TOP2B,GORASP2,PRPF3,BRCA1,SRSF5,ANLN,UBE2I,SCYL2,SH3GLB1,CDK5,SUB1,SEPT1,SURF4,RBM25,SAFB,BUD31,ZNF326,TRA2B,SEPT11,CDC5L |
| 3.231e-03 | -5.74 | GSE40274_SATB1_VS_FOXP3_AND_SATB1_TRANSDUCED_ACTIVATED_CD4_TCELL_UP | MSigDB lists | GSE40274_SATB1_VS_FOXP3_AND_SATB1_TRANSDUCED_ACTIVATED_CD4_TCELL_UP | 162 | 38 | 17377 | 2626 |
DDX58,UNK,CORO7,GPR132,RAF1,SNX15,MRPS26,CTCF,SLC4A2,NHLRC3,NCKAP1,PAPOLA,MTMR4,TBC1D14,FIZ1,ARHGEF1,PPP1R12C,ORAI1,ECD,CITED2,ADAM17,ETV3,NSDHL,TMEM126B,RBM38,RDH11,MYO1F,BRMS1,CERS6,FAM3C,PML,FKBP5,NR2F2,EHD4,PLOD3,E2F2,ANXA11,GPATCH4 |
| 3.232e-03 | -5.73 | BRUINS_UVC_RESPONSE_EARLY_LATE | MSigDB lists | BRUINS_UVC_RESPONSE_EARLY_LATE | 293 | 62 | 17377 | 2626 |
CTDP1,SMAP1,CDC40,ZCCHC8,UBN1,PPP1R15B,CDT1,C16orf87,SMC6,NENF,IFT27,PMVK,C19orf48,KCMF1,UBLCP1,ARL6IP6,FBXO5,MAT2B,PTPN2,CALM2,SMC3,EXOSC7,MED10,ATG3,SIVA1,DNAAF2,BANF1,LPCAT1,EBAG9,MOB4,IFRD1,NASP,DENND1B,PCGF6,E2F3,LNX2,ARID1A,RAB3IP,TAZ,CHCHD6,RPSA,RBM38,EIF3A,DTWD1,HSPBP1,TRIM26,AHNAK,RAD18,TXNDC16,CCDC6,NIP7,SNAP23,PTER,TULP3,MAP4,PPP1R11,USF2,MAPK1,PPP2R2D,ZC3HC1,SSSCA1,FUBP1 |
| 3.234e-03 | -5.73 | AMIT_EGF_RESPONSE_60_HELA | MSigDB lists | AMIT_EGF_RESPONSE_60_HELA | 43 | 14 | 17377 | 2626 |
MOAP1,HSPH1,KLF10,PTPN11,DNAJC24,NCKAP1,DCUN1D4,FXR1,CITED2,SLC20A1,TIPARP,KLF6,RHOB,ATG4A |
| 3.234e-03 | -5.73 | GO_PROTEIN_DEACETYLASE_ACTIVITY | MSigDB lists | GO_PROTEIN_DEACETYLASE_ACTIVITY | 43 | 14 | 17377 | 2626 |
BRMS1,ATXN3,CHD3,HDAC7,MTA1,MTA2,RCOR1,SIRT2,RBBP4,MBD3,SAP30L,ARID4A,HDAC2,SAP30 |
| 3.236e-03 | -5.73 | multivesicular body assembly | biological process | GO:0036258 | 30 | 11 | 17256 | 2622 |
CHMP2A,CHMP4A,HGS,PDCD6IP,CHMP4B,VPS4A,CHMP2B,CHMP7,RAB11A,STAM,VPS25 |
| 3.236e-03 | -5.73 | tricarboxylic acid cycle | biological process | GO:0006099 | 30 | 11 | 17256 | 2622 |
SDHB,SUCLG1,MDH2,IDH3A,CS,SUCLG2,DHTKD1,MDH1,OGDH,IDH3B,SDHA |
| 3.245e-03 | -5.73 | SWEET_LUNG_CANCER_KRAS_UP | MSigDB lists | SWEET_LUNG_CANCER_KRAS_UP | 464 | 92 | 17377 | 2626 |
ST13,ANK3,SND1,FKBP2,UBQLN2,BRIX1,MIEN1,PAPOLA,PRNP,CYHR1,SHC1,SIVA1,CYB5R1,ADCY7,ACSL5,LAP3,CPOX,ATP6V0A1,SLC25A5,PON2,ZNF282,HHEX,ATP1A1,AXIN1,ATP6V0C,CLU,MAPK1,SLC25A39,HSPH1,RPS2,MAPRE1,PHB2,SRSF6,DAP,GNE,CDK2AP2,UBXN1,ARGLU1,EIF2AK4,PSEN1,MAN1A1,GNS,GOLM1,SLC31A1,VASP,CTSS,VMP1,RRBP1,TANK,BRD7,OSTF1,MDFIC,CLDND1,CITED2,LPCAT1,SLC12A2,PABPC1,ATP6V0D1,EEF1D,KDELR1,HMGN1,FAM49B,TSTA3,ELL2,NUDT4,PIP4K2C,CAMSAP1,LDHA,RPL8,RPL6,KRAS,MTX1,ZDHHC3,HSPA1B,RDH11,RPL36,PTPRF,PLD3,NEK1,FNTA,FAM3C,NFIL3,ACLY,SLC16A1,LY75,SLAIN1,CTSA,PSAP,GPI,ATP6V1C1,HEXA,TOB1 |
| 3.248e-03 | -5.73 | YAMASHITA_LIVER_CANCER_WITH_EPCAM_UP | MSigDB lists | YAMASHITA_LIVER_CANCER_WITH_EPCAM_UP | 52 | 16 | 17377 | 2626 |
GNAS,SCARB2,RPL29,TOMM20,RPL35,RPL17,RPS27A,CPOX,RPS10,RPL6,RPS24,AHCY,XPO7,MRPL3,RPSA,RPL23A |
| 3.248e-03 | -5.73 | GSE14769_UNSTIM_VS_360MIN_LPS_BMDM_UP | MSigDB lists | GSE14769_UNSTIM_VS_360MIN_LPS_BMDM_UP | 178 | 41 | 17377 | 2626 |
POLA2,PHB2,MDH2,LETMD1,MXD4,SLC35B2,STMN1,MEAF6,NUP205,ERH,PA2G4,CD3EAP,DUT,PHTF1,YBX1,MRPL11,PRADC1,S100A6,KCNAB2,NUDC,VPS13B,PTPN18,RHOA,NQO2,RDH10,KIAA0930,PSMA1,GAR1,MTR,ZDHHC3,ASF1B,ECH1,ADSS,PRDX3,PRMT7,ZRANB2,NDUFS5,ACADM,CPEB2,FAF1,ATMIN |
| 3.248e-03 | -5.73 | GSE3982_EOSINOPHIL_VS_NKCELL_DN | MSigDB lists | GSE3982_EOSINOPHIL_VS_NKCELL_DN | 178 | 41 | 17377 | 2626 |
SLC12A7,GCLM,CAST,OLA1,RACGAP1,SNRPD3,PARN,HMG20A,ZNF473,LRRC8D,MRPL34,SUCLG2,KIFAP3,APOOL,MAP3K14,MINPP1,FBL,IFT46,TRIM14,MLST8,CYFIP1,ABCF2,SEPT8,RANGAP1,MRPL16,MTX1,SMC2,UBE4B,AMZ2,NSA2,FBXO21,PEX5,JAK1,PROSER1,IARS2,WDR7,MDH1,TERF1,MRPL3,RNF139,IFI16 |
| 3.253e-03 | -5.73 | postsynaptic recycling endosome | cellular component | GO:0098837 | 3 | 3 | 18223 | 2701 |
GRIPAP1,RAB11A,RAB4A |
| 3.253e-03 | -5.73 | Rb-E2F complex | cellular component | GO:0035189 | 3 | 3 | 18223 | 2701 |
RB1,PRMT2,E2F1 |
| 3.253e-03 | -5.73 | nuclear pore inner ring | cellular component | GO:0044611 | 3 | 3 | 18223 | 2701 |
NUP155,NUP188,NUP205 |
| 3.253e-03 | -5.73 | SLIK (SAGA-like) complex | cellular component | GO:0046695 | 3 | 3 | 18223 | 2701 |
TAF6L,TAF12,TAF6 |
| 3.253e-03 | -5.73 | plasma membrane respiratory chain complex I | cellular component | GO:0045272 | 3 | 3 | 18223 | 2701 |
NDUFV2,NDUFS1,NDUFS7 |
| 3.256e-03 | -5.73 | RNA polymerase II, eukaryotes | KEGG pathways | M00180 | 14 | 7 | 7161 | 1149 |
POLR2I,POLR2J,POLR2G,POLR2L,POLR2K,POLR2A,POLR2D |
| 3.256e-03 | -5.73 | Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate | KEGG pathways | hsa_M00011 | 14 | 7 | 7161 | 1149 |
SUCLG2,SDHB,MDH1,OGDH,SUCLG1,SDHA,MDH2 |
| 3.256e-03 | -5.73 | RNA polymerase II, eukaryotes | KEGG pathways | hsa_M00180 | 14 | 7 | 7161 | 1149 |
POLR2I,POLR2J,POLR2G,POLR2L,POLR2K,POLR2A,POLR2D |
| 3.256e-03 | -5.73 | Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate | KEGG pathways | M00011 | 14 | 7 | 7161 | 1149 |
SUCLG2,SDHB,MDH1,OGDH,SUCLG1,SDHA,MDH2 |
| 3.258e-03 | -5.73 | positive regulation of cellular amide metabolic process | biological process | GO:0034250 | 130 | 32 | 17256 | 2622 |
FAM129A,EIF3D,HABP4,DHX9,YTHDF3,EIF2AK4,METTL3,APP,PAIP1,FASTKD3,EIF4A3,MRPS27,RBM3,PABPC1,NSUN4,EIF5A,PLK3,COA3,RHOA,POLR2G,CDC123,NCK1,POLR2D,CIRBP,FXR1,SOX4,SERP1,PICALM,RPS9,MAPK3,CLU,MAPK1 |
| 3.259e-03 | -5.73 | small ribosomal subunit | cellular component | GO:0015935 | 72 | 20 | 18223 | 2701 |
RPS15,RPS2,MRPL42,MRPS2,MRPS15,RPS10,MRPS26,MRPS10,RPS24,EIF2A,MRPS14,RPS9,RPSA,MCTS1,DAP3,RPS27A,RPS14,EIF2D,MRPS27,RPS26 |
| 3.264e-03 | -5.72 | G2/M Checkpoints | REACTOME pathways | R-HSA-69481 | 169 | 42 | 10287 | 1696 |
MCM10,CLSPN,BABAM1,DBF4,RMI2,ORC1,BLM,CCNB1,PSMD9,RMI1,RPA2,PSMD2,PSMD1,BABAM2,PSMA6,MCM5,GTSE1,ORC3,RFC3,PSMA8,TOP3A,PSMB7,PSMA1,CDC6,PKMYT1,BRCA1,MCM2,PSMB9,RFC2,PSMB3,PSMC4,RPA1,RPS27A,PSMD8,PSMD3,H2AFX,YWHAZ,CHEK2,CDK2,YWHAH,CCNB2,PSMC1 |
| 3.281e-03 | -5.72 | REACTOME_SIGNALING_BY_NOTCH1 | MSigDB lists | REACTOME_SIGNALING_BY_NOTCH1 | 66 | 19 | 17377 | 2626 |
MIB2,CCNC,NCOR2,ADAM17,KAT2A,ADAM10,APH1A,RBX1,CUL1,PSEN1,APH1B,RPS27A,HDAC7,DTX4,RBPJ,MAML1,ARRB2,HDAC2,NUMB |
| 3.283e-03 | -5.72 | negative regulation of protein modification by small protein conjugation or removal | biological process | GO:1903321 | 80 | 22 | 17256 | 2622 |
TRIP12,TNFAIP3,UBXN1,GTPBP4,DNAJA1,SOX4,PSEN1,HMG20A,PARK7,MAD2L2,ISG15,HSPA1B,FBXO5,RPL11,CDK5,PLAA,GPS2,LIMK1,OGT,PARP10,ARRB2,CHP1 |
| 3.287e-03 | -5.72 | human chr7p22.1 | chromosome location | human chr7p22.1 | 47 | 12 | 26185 | 2809 |
FOXK1,ZNF316,CCZ1B,CCZ1,USP42,RAC1,PMS2,ACTB,EIF2AK1,WIPI2,TNRC18,C7orf26 |
| 3.291e-03 | -5.72 | regulation of cellular amino acid metabolic process | biological process | GO:0006521 | 61 | 18 | 17256 | 2622 |
NQO1,PSMA8,PSMB7,PSMA1,PSMD9,PSMB9,ODC1,PARK7,PSMB3,PSMC4,PSMD2,PSMA6,PSMD1,PSMD8,PSMD3,OAZ2,OAZ1,PSMC1 |
| 3.292e-03 | -5.72 | site of double-strand break | cellular component | GO:0035861 | 35 | 12 | 18223 | 2701 |
RFWD3,RPA2,PAXX,RAD18,HELB,H2AFX,SMC6,ATF2,SLF1,SLF2,RNF169,PRPF19 |
| 3.292e-03 | -5.72 | ER-HER-positive_carcinoma | COSMIC cancer mutations | ER-HER-positive_carcinoma | 3 | 3 | 17385 | 2587 |
ARID1A,GPBP1L1,ZNF700 |
| 3.292e-03 | -5.72 | pancreas-ampulla_of_Vater-carcinoid-endocrine_tumour | COSMIC cancer mutations | pancreas-ampulla_of_Vater-carcinoid-endocrine_tumour | 3 | 3 | 17385 | 2587 |
KRAS,NRAS,HRAS |
| 3.292e-03 | -5.72 | skin-face-carcinoma-squamous_cell_carcinoma_BRAF_inhibitor_related | COSMIC cancer mutations | skin-face-carcinoma-squamous_cell_carcinoma_BRAF_inhibitor_related | 3 | 3 | 17385 | 2587 |
KRAS,NRAS,HRAS |
| 3.292e-03 | -5.72 | salivary_gland-parotid-carcinoma-basal_cell_carcinoma | COSMIC cancer mutations | salivary_gland-parotid-carcinoma-basal_cell_carcinoma | 3 | 3 | 17385 | 2587 |
KRAS,NRAS,HRAS |
| 3.292e-03 | -5.72 | skin-neck-carcinoma-squamous_cell_carcinoma_BRAF_inhibitor_related | COSMIC cancer mutations | skin-neck-carcinoma-squamous_cell_carcinoma_BRAF_inhibitor_related | 3 | 3 | 17385 | 2587 |
KRAS,NRAS,HRAS |
| 3.292e-03 | -5.72 | NS-carcinoma-small_cell_carcinoma | COSMIC cancer mutations | NS-carcinoma-small_cell_carcinoma | 3 | 3 | 17385 | 2587 |
KRAS,NRAS,HRAS |
| 3.292e-03 | -5.72 | salivary_gland-submaxillary-other-mixed_tumour | COSMIC cancer mutations | salivary_gland-submaxillary-other-mixed_tumour | 3 | 3 | 17385 | 2587 |
KRAS,NRAS,HRAS |
| 3.292e-03 | -5.72 | upper_aerodigestive_tract-trachea-carcinoma-adenocarcinoma | COSMIC cancer mutations | upper_aerodigestive_tract-trachea-carcinoma-adenocarcinoma | 3 | 3 | 17385 | 2587 |
KRAS,NRAS,HRAS |
| 3.292e-03 | -5.72 | autoimmune_leukoproliferative_disease | COSMIC cancer mutations | autoimmune_leukoproliferative_disease | 3 | 3 | 17385 | 2587 |
KRAS,NRAS,HRAS |
| 3.292e-03 | -5.72 | pancreas-other-papillary_cystic_tumour | COSMIC cancer mutations | pancreas-other-papillary_cystic_tumour | 3 | 3 | 17385 | 2587 |
KRAS,NRAS,HRAS |
| 3.292e-03 | -5.72 | salivary_gland-minor-carcinoma-adenocarcinoma | COSMIC cancer mutations | salivary_gland-minor-carcinoma-adenocarcinoma | 3 | 3 | 17385 | 2587 |
KRAS,NRAS,HRAS |
| 3.292e-03 | -5.72 | skin-sole-malignant_melanoma-superficial_spreading | COSMIC cancer mutations | skin-sole-malignant_melanoma-superficial_spreading | 3 | 3 | 17385 | 2587 |
KRAS,NRAS,HRAS |
| 3.292e-03 | -5.72 | salivary_gland-sublingual-carcinoma-adenocarcinoma | COSMIC cancer mutations | salivary_gland-sublingual-carcinoma-adenocarcinoma | 3 | 3 | 17385 | 2587 |
KRAS,NRAS,HRAS |
| 3.292e-03 | -5.72 | pituitary-carcinoma-PRL | COSMIC cancer mutations | pituitary-carcinoma-PRL | 3 | 3 | 17385 | 2587 |
KRAS,NRAS,HRAS |
| 3.292e-03 | -5.72 | skin-conjunctiva-benign_melanocytic_nevus | COSMIC cancer mutations | skin-conjunctiva-benign_melanocytic_nevus | 3 | 3 | 17385 | 2587 |
KRAS,NRAS,HRAS |
| 3.292e-03 | -5.72 | soft_tissue-fibrous_tissue_and_uncertain_origin-malignant_fibrous_histiocytoma-pleomorphic_sarcoma-giant_cell | COSMIC cancer mutations | soft_tissue-fibrous_tissue_and_uncertain_origin-malignant_fibrous_histiocytoma-pleomorphic_sarcoma-giant_cell | 3 | 3 | 17385 | 2587 |
KRAS,NRAS,HRAS |
| 3.292e-03 | -5.72 | biliary_tract-bile_duct-carcinoma-squamous_cell_carcinoma | COSMIC cancer mutations | biliary_tract-bile_duct-carcinoma-squamous_cell_carcinoma | 3 | 3 | 17385 | 2587 |
KRAS,NRAS,HRAS |
| 3.292e-03 | -5.72 | bone-mandible-cemento-ossifying_fibroma | COSMIC cancer mutations | bone-mandible-cemento-ossifying_fibroma | 3 | 3 | 17385 | 2587 |
GNAS,FUS,CDC73 |
| 3.292e-03 | -5.72 | acanthoma_BRAF_inhibitor_related | COSMIC cancer mutations | acanthoma_BRAF_inhibitor_related | 3 | 3 | 17385 | 2587 |
KRAS,NRAS,HRAS |
| 3.292e-03 | -5.72 | giant_cell | COSMIC cancer mutations | giant_cell | 3 | 3 | 17385 | 2587 |
KRAS,NRAS,HRAS |
| 3.292e-03 | -5.72 | skin-neck-other-keratoacanthoma_BRAF_inhibitor_related | COSMIC cancer mutations | skin-neck-other-keratoacanthoma_BRAF_inhibitor_related | 3 | 3 | 17385 | 2587 |
KRAS,NRAS,HRAS |
| 3.292e-03 | -5.72 | pituitary-carcinoma-ACTH_non_functioning | COSMIC cancer mutations | pituitary-carcinoma-ACTH_non_functioning | 3 | 3 | 17385 | 2587 |
KRAS,NRAS,HRAS |
| 3.292e-03 | -5.72 | soft_tissue-fat-lipoma-spindle_cell | COSMIC cancer mutations | soft_tissue-fat-lipoma-spindle_cell | 3 | 3 | 17385 | 2587 |
GNAS,RB1,FUS |
| 3.292e-03 | -5.72 | haematopoietic_and_lymphoid_tissue-other-autoimmune_leukoproliferative_disease | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-other-autoimmune_leukoproliferative_disease | 3 | 3 | 17385 | 2587 |
KRAS,NRAS,HRAS |
| 3.292e-03 | -5.72 | upper_aerodigestive_tract-larynx-other-papilloma | COSMIC cancer mutations | upper_aerodigestive_tract-larynx-other-papilloma | 3 | 3 | 17385 | 2587 |
STK11,PTEN,CDKN2A |
| 3.292e-03 | -5.72 | skin-trunk-carcinoma-squamous_cell_carcinoma_BRAF_inhibitor_related | COSMIC cancer mutations | skin-trunk-carcinoma-squamous_cell_carcinoma_BRAF_inhibitor_related | 3 | 3 | 17385 | 2587 |
KRAS,NRAS,HRAS |
| 3.292e-03 | -5.72 | skin-eye-carcinoma-squamous_cell_carcinoma_BRAF_inhibitor_related | COSMIC cancer mutations | skin-eye-carcinoma-squamous_cell_carcinoma_BRAF_inhibitor_related | 3 | 3 | 17385 | 2587 |
KRAS,NRAS,HRAS |
| 3.292e-03 | -5.72 | anaplastic_renal_cell_carcinoma | COSMIC cancer mutations | anaplastic_renal_cell_carcinoma | 3 | 3 | 17385 | 2587 |
KRAS,NRAS,HRAS |
| 3.292e-03 | -5.72 | skin-trunk-other-keratoacanthoma_BRAF_inhibitor_related | COSMIC cancer mutations | skin-trunk-other-keratoacanthoma_BRAF_inhibitor_related | 3 | 3 | 17385 | 2587 |
KRAS,NRAS,HRAS |
| 3.292e-03 | -5.72 | upper_aerodigestive_tract-mouth-carcinoma-mixed_adenosquamous_carcinoma | COSMIC cancer mutations | upper_aerodigestive_tract-mouth-carcinoma-mixed_adenosquamous_carcinoma | 3 | 3 | 17385 | 2587 |
KRAS,NRAS,HRAS |
| 3.292e-03 | -5.72 | skin-ear-carcinoma-squamous_cell_carcinoma_BRAF_inhibitor_related | COSMIC cancer mutations | skin-ear-carcinoma-squamous_cell_carcinoma_BRAF_inhibitor_related | 3 | 3 | 17385 | 2587 |
KRAS,NRAS,HRAS |
| 3.292e-03 | -5.72 | parosteal | COSMIC cancer mutations | parosteal | 3 | 3 | 17385 | 2587 |
GNAS,RB1,CDKN2A |
| 3.292e-03 | -5.72 | kidney-carcinoma-anaplastic_renal_cell_carcinoma | COSMIC cancer mutations | kidney-carcinoma-anaplastic_renal_cell_carcinoma | 3 | 3 | 17385 | 2587 |
KRAS,NRAS,HRAS |
| 3.292e-03 | -5.72 | breast-carcinoma-ER-HER-positive_carcinoma | COSMIC cancer mutations | breast-carcinoma-ER-HER-positive_carcinoma | 3 | 3 | 17385 | 2587 |
ARID1A,GPBP1L1,ZNF700 |
| 3.292e-03 | -5.72 | mixed_tumour | COSMIC cancer mutations | mixed_tumour | 3 | 3 | 17385 | 2587 |
KRAS,NRAS,HRAS |
| 3.292e-03 | -5.72 | biliary_tract-bile_duct-carcinoma-undifferentiated_carcinoma | COSMIC cancer mutations | biliary_tract-bile_duct-carcinoma-undifferentiated_carcinoma | 3 | 3 | 17385 | 2587 |
KRAS,NRAS,HRAS |
| 3.292e-03 | -5.72 | cervix-adenoma_malignum | COSMIC cancer mutations | cervix-adenoma_malignum | 3 | 3 | 17385 | 2587 |
GNAS,KRAS,STK11 |
| 3.292e-03 | -5.72 | lobular_endocervical_glandular_hyperplasia | COSMIC cancer mutations | lobular_endocervical_glandular_hyperplasia | 3 | 3 | 17385 | 2587 |
GNAS,KRAS,STK11 |
| 3.292e-03 | -5.72 | skin-face-other-acanthoma_BRAF_inhibitor_related | COSMIC cancer mutations | skin-face-other-acanthoma_BRAF_inhibitor_related | 3 | 3 | 17385 | 2587 |
KRAS,NRAS,HRAS |
| 3.292e-03 | -5.72 | skin-lower_leg-carcinoma-squamous_cell_carcinoma_BRAF_inhibitor_related | COSMIC cancer mutations | skin-lower_leg-carcinoma-squamous_cell_carcinoma_BRAF_inhibitor_related | 3 | 3 | 17385 | 2587 |
KRAS,NRAS,HRAS |
| 3.292e-03 | -5.72 | central_nervous_system-brain-glioma-ependymoma_Grade_I | COSMIC cancer mutations | central_nervous_system-brain-glioma-ependymoma_Grade_I | 3 | 3 | 17385 | 2587 |
TSC1,TSC2,CDKN2A |
| 3.292e-03 | -5.72 | cervix-other-lobular_endocervical_glandular_hyperplasia | COSMIC cancer mutations | cervix-other-lobular_endocervical_glandular_hyperplasia | 3 | 3 | 17385 | 2587 |
GNAS,KRAS,STK11 |
| 3.292e-03 | -5.72 | soft_tissue-fibrous_tissue_and_uncertain_origin-fibroxanthoma | COSMIC cancer mutations | soft_tissue-fibrous_tissue_and_uncertain_origin-fibroxanthoma | 3 | 3 | 17385 | 2587 |
KRAS,NRAS,HRAS |
| 3.292e-03 | -5.72 | adenoma_malignum | COSMIC cancer mutations | adenoma_malignum | 3 | 3 | 17385 | 2587 |
GNAS,KRAS,STK11 |
| 3.292e-03 | -5.72 | skin-neck-carcinoma-Merkel_cell_carcinoma | COSMIC cancer mutations | skin-neck-carcinoma-Merkel_cell_carcinoma | 3 | 3 | 17385 | 2587 |
RB1,KRAS,NRAS |
| 3.292e-03 | -5.72 | adrenal_gland-adrenal_cortical_adenoma-aldosterone_producing | COSMIC cancer mutations | adrenal_gland-adrenal_cortical_adenoma-aldosterone_producing | 3 | 3 | 17385 | 2587 |
KRAS,NRAS,HRAS |
| 3.292e-03 | -5.72 | skin-knee-other-keratoacanthoma_BRAF_inhibitor_related | COSMIC cancer mutations | skin-knee-other-keratoacanthoma_BRAF_inhibitor_related | 3 | 3 | 17385 | 2587 |
KRAS,NRAS,HRAS |
| 3.292e-03 | -5.72 | salivary_gland-submaxillary-carcinoma-adenocarcinoma | COSMIC cancer mutations | salivary_gland-submaxillary-carcinoma-adenocarcinoma | 3 | 3 | 17385 | 2587 |
KRAS,NRAS,HRAS |
| 3.292e-03 | -5.72 | skin-foot-carcinoma-squamous_cell_carcinoma | COSMIC cancer mutations | skin-foot-carcinoma-squamous_cell_carcinoma | 3 | 3 | 17385 | 2587 |
KRAS,NRAS,HRAS |
| 3.292e-03 | -5.72 | keratoacanthoma_BRAF_inhibitor_related | COSMIC cancer mutations | keratoacanthoma_BRAF_inhibitor_related | 3 | 3 | 17385 | 2587 |
KRAS,NRAS,HRAS |
| 3.292e-03 | -5.72 | skin-malignant_melanoma-mucosal_lentiginous | COSMIC cancer mutations | skin-malignant_melanoma-mucosal_lentiginous | 3 | 3 | 17385 | 2587 |
KRAS,NRAS,HRAS |
| 3.292e-03 | -5.72 | papillary_cystic_tumour | COSMIC cancer mutations | papillary_cystic_tumour | 3 | 3 | 17385 | 2587 |
KRAS,NRAS,HRAS |
| 3.296e-03 | -5.71 | kinesin complex | cellular component | GO:0005871 | 53 | 16 | 18223 | 2701 |
KIF3B,KIF15,KLC1,KIF23,KIF2C,KIF11,KIF2A,KIFC1,KIF5B,KIF18A,KIF18B,KIF13B,KIF14,KIF22,KIFAP3,NDE1 |
| 3.299e-03 | -5.71 | ATP synthesis coupled proton transport | biological process | GO:0015986 | 26 | 10 | 17256 | 2622 |
COX5B,ATP5MC3,ATP6V0A2,ATP6V0A1,ATP5F1B,CYC1,ATP5F1A,ATP5MF,ATP5PF,STOML2 |
| 3.299e-03 | -5.71 | receptor catabolic process | biological process | GO:0032801 | 26 | 10 | 17256 | 2622 |
CDK5,SNX25,TGFB1,AP2B1,ZNRF3,SMURF1,BECN1,AP2S1,SH3GLB1,CAPN1 |
| 3.299e-03 | -5.71 | regulation of androgen receptor signaling pathway | biological process | GO:0060765 | 26 | 10 | 17256 | 2622 |
RWDD1,PIAS2,BUD31,SMARCA4,DDX5,PRMT2,SAFB2,ARRB2,RNF14,PARK7 |
| 3.299e-03 | -5.71 | energy coupled proton transport, down electrochemical gradient | biological process | GO:0015985 | 26 | 10 | 17256 | 2622 |
COX5B,ATP5MC3,ATP6V0A2,ATP6V0A1,ATP5F1B,CYC1,ATP5F1A,ATP5MF,ATP5PF,STOML2 |
| 3.299e-03 | -5.71 | membrane protein intracellular domain proteolysis | biological process | GO:0031293 | 26 | 10 | 17256 | 2622 |
TGFB1,ADAM17,ADAM10,APH1A,YBX1,PSEN1,APH1B,SPPL2B,RHBDD1,SPPL2A |
| 3.304e-03 | -5.71 | negative regulation of phosphorus metabolic process | biological process | GO:0010563 | 613 | 118 | 17256 | 2622 |
ZBED3,FGFR1OP,PPP1R37,ASH1L,GGNBP2,TSC2,FOXM1,NF1,DYNLL1,FAM129A,PPP1R15B,ENSA,SIRT2,CCNB1,PPP1R16B,LYN,DUSP22,PARK7,PRNP,TERF2IP,CALM2,CDKN2C,PIN1,PPME1,PIK3R2,SOCS6,PPP1R12C,CDKN1B,CRY2,TARDBP,GPD1L,STRAP,CTDSP2,CHP1,PLK1,ANKLE2,SNX25,BAK1,PPIF,NCK1,PBK,GMFB,EZR,LRP5,PKMYT1,DNAJA1,EIF3A,PLEKHF2,SOCS7,PPP2CA,HHEX,DNAJC10,PPP2R5A,CORO1C,STK38,GADD45B,SOCS4,DVL1,ROCK1,PPP5C,ARRB2,SMAD4,PARD3,PDCD4,HSPH1,ZCCHC9,PPP1R2,PPP1R12A,GMFG,CIB1,AKT1S1,RGS2,PSEN1,VPS25,PTPN2,FKBP1A,TFAP4,RB1,TIGAR,PTEN,PPP1R8,FBXO7,DUS2,H2AFY,PIK3IP1,MVP,GNAI2,LPCAT1,STAT3,SOCS5,PDPK1,TGFB1,PPP1R9B,RHOA,TNFAIP3,ZMYND11,PRKDC,PRKAR1B,GBA,WDR81,MEN1,MASTL,LEMD2,SH3BP5,MBIP,GPS2,DUSP3,CSK,PRDX3,QARS,PPP1R11,NUP62,CABIN1,NR2F2,IGBP1,HIPK3,CDKN2A,EGLN1 |
| 3.306e-03 | -5.71 | malignant_melanoma | COSMIC cancer mutations | malignant_melanoma | 16380 | 2467 | 17385 | 2587 |
HECA,ZBTB10,ABCC10,HEXB,TGOLN2,CCNL2,FBXO22,EEF2K,THAP4,RAD23B,ATP13A3,DNM2,ZNRD1,FTSJ3,USP34,CCDC57,ERCC1,NRAS,EHMT1,KIF15,HNRNPF,WDHD1,MIER2,DIDO1,MCM2,RAB22A,SMAD2,MID1IP1,RPS27A,MYO18A,OGT,MPV17,SMAD1,ZNF75A,ANXA11,SLC25A33,ZNF720,GGA1,MUM1,CCZ1,TRIO,CUTA,RAB23,KCTD17,HAUS4,EIF2AK4,APH1B,PARN,CDC73,MYL6B,ATG4A,TMEM179B,ERV3-1,PDXP,SMC3,GEMIN4,MVP,NUP85,PPP6R1,PABPC1,NSUN4,PPA1,IFRD1,AGGF1,FOXK1,RBM42,GTPBP4,MAP7D1,MRPL16,ELK1,EIF4H,RDH11,MAGED2,KPNA1,ETS2,TYW5,WIPI2,RUFY3,PDLIM5,ACSF2,FAM72D,EXOC3,RHOG,STARD7,C5orf30,VTI1A,SLC35B2,INO80E,LCLAT1,RCOR3,CPNE3,KIAA1147,RBM23,ZNF420,AHCTF1,TBC1D22A,TBC1D14,GMEB1,NSFL1C,SEPT11,ZNF226,GPD1L,ZC3H3,ARL5A,PDCL3,SNX8,ERMP1,EID1,IDH3A,POLR2D,HTATIP2,MEF2D,TMEM147,GSTCD,TANC1,MAT2A,VPS26B,NSMCE2,CORO1C,CAMKMT,PPP5C,PITRM1,TUBB,COMMD10,ZNF445,SRSF6,HABP4,CCM2,FLOT1,BTN3A1,ATG2B,ABHD14B,PPP1R3B,GOLM1,ZBTB45,HUWE1,ZNF260,NAA50,ANXA5,LTN1,KANSL2,UBE3B,NAP1L4,ZNF710,ST8SIA2,MED22,SPTAN1,STAU1,DDX24,TCTEX1D2,TACC1,MRS2,LDHA,HEBP2,LLPH,RAB3IP,TTC33,PICALM,SH3BP5,SLC19A1,ACOX1,FAM3C,AEN,PARP10,YWHAH,THAP5,GPATCH4,FAM129A,TRIM11,YTHDC2,SNX15,RBM8A,ENSA,NENF,SND1,RUFY1,TRIM65,ZER1,PRNP,KRR1,RAB8A,NUP210,NT5DC1,NOC2L,EIF5,TACC3,RYBP,VPS13B,PTPN18,MIOS,MBLAC2,SNRPB,CDC6,UTP3,PBRM1,ODC1,USP21,TRAM2,FBXO28,BCL7C,ARRDC1,ADAM9,DVL1,NUMB,ZNF564,FUBP1,C1orf74,CTU2,PARP12,ZCCHC9,CENPF,LAMTOR3,NCKAP1,RSAD1,TNS3,SUB1,RINL,SSBP3,KIF13B,MBD2,XPA,AHCY,RBM3,GLE1,LRSAM1,HDHD2,NTPCR,NSDHL,AMD1,CAMSAP1,ZNF761,METTL22,ICAM2,STYXL1,APPL1,BBS12,ANKRD46,RXRB,SDHB,PCM1,GALNT2,TMEM168,NLRC5,RUVBL2,BTBD10,MYO9A,CCNB2,USP7,GLT8D1,RPLP2,SUCLG1,ARID2,TMX4,SLC2A1,ATP6V1B2,PCBP1,LYN,BCAP31,VAV1,TMEM69,MRPL50,PSMA6,ZNF473,ZNF302,BRPF3,TARDBP,BCAP29,CTDSP2,PRPF19,PPIF,KDM3B,MND1,CLCN3,BIRC3,RAB7A,ANKRD33B,PPIE,CHMP2B,VDAC1,EIF3H,TMEM201,GLOD4,IDE,DHX16,UHRF2,CHMP4B,XRCC3,PARD3,BCL2L12,C19orf53,MCM10,KLHL21,PDAP1,CDCA8,TMX3,ARF1,SLC12A9,TUBGCP2,DNAJB9,HOMER1,WBP1L,POLR1B,RNF5,RBM15B,PPAN,RHOA,RPRD1A,BTAF1,TOP3A,ARHGEF12,PCGF1,DDX23,RAB18,CACNB1,TRIM26,PDCD6,ATP6V1D,L3MBTL3,FAM110A,NEIL3,CTBS,BBX,IMPDH1,NR2F2,PGAM1,HIPK3,IFI16,NUP188,H2AFZ,PNISR,TMEM203,PRKCSH,USP39,UBE2I,PARK7,SLC25A37,ASPHD2,ZNF428,RAB4A,TRA2B,SUCLG2,CISD2,TAF5L,SMARCE1,ZNF800,CDC5L,ZNF524,SGCE,OSBP2,NSUN2,USP22,CLNS1A,EIF3A,ZMYM3,DOT1L,IWS1,ANKRD10,WAS,KIF18B,TPP2,C1orf109,ZMAT3,B4GALT2,PRPF38B,RECQL,C9orf78,EWSR1,GADD45G,RRM1,ACAP1,B4GALT1,CYCS,FAM136A,SUPT7L,TMEM165,NPLOC4,CNOT3,SPAG5,WDR48,RTKN,CEP104,EXOSC7,KLHL5,LRRC8D,PPP4R1,MSH2,PIGG,OSTF1,FBXL7,MRPL40,TNRC18,SYTL3,FAM171A1,APOL1,EIF5A,GCC2,PRIM2,ELL2,RDH10,MFNG,RPS24,GORASP2,CAPZA2,ADRB2,CCT8,MTR,PHF6,PFDN5,SLCO4A1,TTC13,GOLGA2,RBMX,MED15,PIAS2,APPL2,SAMD8,NUDT3,CDKN2A,ZNF511,ATXN3,RAF1,KIAA0232,C2orf49,CD320,EPM2A,CCNA2,MTMR4,TP53BP2,AQR,RBM12B,ILKAP,CDK12,SAP30,BRD4,NARF,LRRC8A,ELP4,ABHD11,PKMYT1,ASB13,TRIM28,SUPT16H,EIF3K,CHMP4A,CBWD1,ATF6,XRCC4,ADAM23,PRPF4B,NDUFS1,DEPDC1,MECP2,SECISBP2,HMG20A,WWP2,JAKMIP1,SLC25A36,CCNK,DNAJC8,ELP5,AXIN2,CITED2,JMJD4,KAT2A,RABIF,ADSL,PACS1,BMS1,KCNQ1,OTUD3,ARSK,MACF1,KIF11,COMMD4,KLF6,SMAP2,FADD,SH3GLB1,MYO1F,CBX3,TMEM127,INF2,PPP1R11,DUSP11,DDX5,WDR62,TAF6,ESPL1,PURA,DDB1,DEF6,FAM83G,IPO4,UBL3,NAT9,PIGM,LYRM4,GPR132,UBE2Q1,PTP4A3,MRPL19,ZNF696,SF3B2,PCYOX1L,CDC42,SYNM,GOT2,JAZF1,HADHB,RPF2,SLC35C2,CNNM3,CARM1,SRPK2,WDR41,LARS,ZCCHC10,CCDC138,LRBA,TMEM216,SUMF2,KMT2C,OGFR,PRPSAP1,ASF1B,RPL37,MAN2A2,EIF4ENIF1,U2SURP,MIA2,ZNF268,VPS4A,ATP6V0E1,PPP1R2,PM20D2,XPNPEP3,RGS2,LYAR,FAM89B,POLR2I,TRAFD1,SUGP2,GBA,EIF2A,SYVN1,DAPK3,ARHGAP15,MASTL,UAP1,NFIL3,FN3KRP,YWHAZ,CTSA,TMEM14A,TOB1,TSEN15,ADNP2,TCF12,PRKAB1,MDH2,SMARCA4,ORC1,RRN3,UBXN2A,IARS,CD3EAP,KIF14,EXOSC1,CS,CLTB,DNAL4,CSTF1,POU2AF1,UBQLN4,NXT1,HPDL,PGGT1B,SELPLG,SMU1,ATXN1,GLO1,OGDH,BICD2,CADM1,EDEM2,HERPUD2,TOLLIP,FANCE,MBD3,PDHX,RPS9,ALKBH6,DUS3L,ARNTL,ANP32E,FKBP5,TMEM101,CCDC125,ABCA1,PDCD2L,GCLM,RAE1,DCTN2,NUP54,CHIC2,PAWR,MXD4,DCUN1D4,PIP4K2A,XPR1,FERMT3,KIF5B,KLHL20,SEC24C,RRBP1,ARHGEF2,ANP32A,LDLRAD3,STAT3,MYO5A,NIPAL3,AMPD2,TXNL1,PHF20L1,DCAF6,FAM49B,TMEM39A,ATP2C1,RFFL,COG1,RCOR1,PRMT2,TFEB,LEMD2,UPF1,ELMO1,ZC3H7B,DTX4,ZMIZ1,TERF1,HRAS,CCDC93,FGFR1OP,TMED7,PIGQ,AGPAT1,CNTROB,PPP1R16B,MIS12,GSDMB,TTC9C,PDS5B,NUP153,SENP1,PGAP2,TMEM115,PLEKHM3,DCUN1D5,PLEKHF2,BRMS1,PWWP2B,TRIM47,WDR11,AXIN1,SMG9,TRIM52,LONP2,NDUFV2,PHF23,CERK,SLC4A2,EZH1,ITGB5,LMNA,MCTS1,DDX56,EIF2S2,SLC38A5,FOXN2,CARS2,PRRC2A,C16orf72,RB1CC1,ZMYND11,PGS1,MYBL2,UHRF1BP1,SRSF5,MPG,MATR3,CYB5A,NCDN,POLR2J,SETD3,TEX30,PTAR1,CNOT6,NDE1,EGLN1,ZNF207,ANKRD27,ABCA3,SARNP,IVNS1ABP,RMI2,MON1B,TMEM97,NIT2,NUF2,ZNF267,TCF19,TMEM161B,KTN1,APP,PRKD3,CLUAP1,ATP2A2,UTP18,GRSF1,DUT,ZCCHC2,ANAPC7,RNF19A,FAM76B,CLN6,TMEM9,GCC1,RNF169,ADCY7,ATP6V1G1,ENPP4,RNPS1,CDCA2,FKBP3,GPR137,DDX17,CHCHD3,PEX5,CDC16,HIPK2,MBOAT1,TICAM1,PDXK,ZBTB11,ANXA6,TMBIM4,GMCL1,UBE4A,IL21R,ETS1,WRB,ZNF92,PNO1,CAPN2,ADD3,SUV39H2,TTLL12,TPCN1,TMX1,LYPLA2,HNRNPM,MFSD12,LDHB,PPP3CA,NUDT8,POLK,JTB,EMP3,MTMR12,ZP3,PDE3B,KIF18A,CCDC6,WNT5B,MAPK6,C4orf46,LY75,SLC25A19,RGL1,PSAP,WDR76,IGBP1,FAF1,COX15,THOC1,AGRN,GNPDA1,GPBP1L1,PPP1R15B,CSNK2A1,EBNA1BP2,GIT2,BIRC2,ATPAF1,DLG5,ABL2,XRCC2,ZFYVE27,MCMBP,PTPRK,CDC37,METTL1,SP3,EXOSC6,HARS,GMFB,ESYT1,ANLN,RAB5B,RHEB,DPYSL3,TBC1D17,TIMM13,CDCA4,TONSL,NRM,NAGLU,ACTB,ZNF45,TMUB1,CTCF,ASAH1,DOCK11,CRLF3,ASXL2,LRRC14,NUS1,SLC27A4,AFF1,MDFIC,MAML1,CYTH1,NQO2,UTP15,EIF2AK1,EIF4G2,ZDHHC3,MOSPD3,ITPRIPL1,CDC27,TBPL1,PRMT7,KCTD7,CYLD,UGP2,COPE,ZADH2,GGPS1,RAD23A,ATP6V0B,PDK2,STRBP,DUS4L,PDCD2,SAP30L,SLC39A9,CLPTM1,RPL29,RPL35,BTG2,DNAJC9,MTMR6,NFATC2,KDM1B,ARL5B,USP36,CCDC127,MRPL2,ATP1A1,CLK3,PSMD3,MAFK,CEP55,NDUFA11,DNAJC17,ZNF436,NCOA1,SLC25A39,ZC3HC1,ZNF146,ATXN7L2,CDC40,GOLIM4,SMAP1,RRP15,GNE,SMC6,ARFIP2,NKRF,CHAC2,BZW2,WRNIP1,SS18L1,CENPM,CAMK2G,MLEC,ZNF202,PPWD1,FAM50B,RHOT2,NEU1,TPD52L2,GOLGA7,TWSG1,GLG1,PGRMC1,FAM126A,RPS6KC1,UBE2C,PPCS,TMEM41B,ZDHHC8,PLXNA1,CCNB1,SLC20A1,COMMD6,POLR3K,C14orf119,ASAP2,SNUPN,CNPY4,PLCL2,TFG,SEH1L,ATG9A,PBK,MKI67,DDX20,AMDHD2,GALNT7,SLC17A5,CCNF,FOXRED1,RBM47,PTER,WDR4,DHTKD1,TRAF5,HDAC2,PWWP2A,HSPH1,LIME1,MAPRE1,CHTF18,ADO,KIF23,SLC35B1,NOTCH2,PMF1,JMY,FKBP1A,SLC31A1,SNX18,ATIC,CTPS1,ATP6V0A2,PIKFYVE,RNF135,LPCAT1,EEF1D,TMED2,PHF10,FTL,DDX28,SIGMAR1,PIP4K2C,FAM133B,RIT1,PLEC,KDM3A,SF3A2,FAS,EPRS,ZNF777,TMEM54,QARS,PPP3R1,TCOF1,NRBP1,CABLES1,DNMT3A,RWDD1,CKLF,TRIP10,SF3B1,RPS6KA1,CAST,SUZ12,RAC1,GPR89A,OLA1,GNB2,FLAD1,APLP2,KDM2A,TNPO2,CDKN1B,TALDO1,ATP13A1,MAPRE2,RFC3,ERF,CUL3,SLBP,KIAA1586,H2AFV,POLG2,GAR1,PSMB9,DHX57,NSA2,HSPA4,MRPL55,JAK1,TBL3,GOLGA8A,SEL1L,H2AFX,KLHDC4,B4GALT3,PDCD11,ATMIN,POLQ,POU3F2,OTUD5,NCOR2,ANKRD13D,PKP4,SCAMP3,BABAM1,CDCA3,SLC25A12,BLM,TMCC3,GTF2F1,RPL17,CRAT,AHSA1,PRC1,UPF2,COPS7B,SLC38A10,CNOT6L,CNPY3,UBE2M,IFT46,TMEM160,TSHZ1,ZFP64,STRIP1,DENND4C,DENND1B,WDR18,RPL8,ILF3,LRRC1,RHOT1,TSR2,MARK2,ECH1,PRDX1,PLD3,NUCB1,FBXO21,GNA12,C1orf131,PRDX3,PFDN4,HNRNPH3,STX18,TFDP1,KHSRP,ASNA1,CPEB2,SSSCA1,VPS29,BYSL,S100PBP,MIB2,IER2,NOP2,UBN1,DCAF15,NF1,FLYWCH2,ALKBH5,MOGS,UBE2Z,TAF6L,BECN1,MAPK14,SNAPC4,RNF103,BCAT2,MBD4,METTL14,ZNHIT6,IMPAD1,RCSD1,PHTF1,SRI,KIF22,ZBTB22,NFU1,OGG1,TRIM14,ELOF1,COPS8,FYTTD1,TRIM8,RRM2,SOX4,ABHD5,UBTF,CXXC4,PAF1,UEVLD,SPATA2,PQBP1,IARS2,ATXN2L,GALNT10,STARD3NL,RPS15,PIGN,AGTRAP,CIB1,XPO7,SRRT,ZNF449,CAPZA1,KIFAP3,BCL2,N4BP2,HP1BP3,VOPP1,THNSL1,ISG15,CAND1,GNAS,TSC1,RBM25,CDCA5,ZFP90,NANP,RBBP4,ZBTB24,SMARCD1,MBD1,WASF2,MMACHC,TOMM20,IFI27L1,MPHOSPH8,HNRNPUL2,CHD1,MEAF6,CCDC50,AKAP8,PARL,RPN2,CHTOP,FAM3A,F2R,SCYL3,ABI1,HTRA2,MOSPD1,RLIM,FAM172A,ZNF500,PSMB7,NLN,WIPF1,BOLA1,BUD13,NDUFB1,PEF1,EIF3G,BTBD1,TAB2,CHCHD1,TULP3,WDR59,CANT1,SCARB1,GAS2,USP11,SMURF1,PPP2R2D,TSPAN5,CDS2,MAGEH1,MRPL42,EYA1,CDK2AP2,MRPS26,LETMD1,KLF13,HDDC2,RGS1,MAN1A1,FBXO5,GART,PELO,TANK,BRD7,MRPL11,SAMD4B,ZDHHC18,GTF3C6,POLR3GL,WDR81,MEN1,ZNF407,MFN2,COX8A,ZRANB2,SRSF3,MBD6,ATP6V1C1,IDH3B,TATDN1,TSC2,LACTB2,CMTM6,RBM4,ZNF275,ANKRD39,RPL23A,CDKN2C,USF1,DNAAF2,MECR,AP1M1,UPRT,CRY2,ECD,RNF26,TIPARP,LRRC59,ANKRD9,RHBDD2,MGAT5,BAK1,ZNF559,RHOBTB3,GABPA,WBP1,NUTF2,ARF4,GINS4,KRIT1,AHNAK,RAD18,PDRG1,RNASEL,CHPF2,PDCD4,SMNDC1,NXT2,HIVEP3,KIAA0100,CLSPN,RHOC,DHX9,PDCD7,PSMD9,HAUS2,COPB2,TFAP4,CD59,RNFT1,RIMS3,MEGF8,EFTUD2,FBXO7,CPSF4,MRPL21,PHKG2,LUC7L2,SRSF11,EIF3L,MTA2,TYW1,USP10,ITM2A,SSR2,BCLAF1,MTX1,SFXN5,FNTA,PDLIM1,TXNDC16,ZNF830,TMEM159,MRPL3,ALS2,FAM72A,TRIM41,KARS,NQO1,POC1A,ANK3,PTTG1,TPX2,TBC1D13,DAZAP2,GLRX3,STMN1,C19orf48,REPS1,ABHD16A,FBXL6,SH3BP1,MTA1,UBA5,CLCN6,INTS12,RPRD1B,SZRD1,CGGBP1,CPNE1,FAM118B,GOPC,E2F3,CIRBP,RPL38,CRNKL1,PFKFB3,GORAB,RAB1A,GIGYF1,TMEM184C,PPP2CA,KIF2A,CCDC14,LSM6,RNF38,SNRPG,DMWD,USP13,MZT1,ZFP91,TRMT6,IP6K2,WDR5,SLC25A43,IFT27,PMVK,NEIL2,RRP36,SRXN1,RPA2,PSMD2,CLIC4,PDCD10,COQ4,ITGB8,ARF5,ARHGEF1,GTF2H2,FBXL19,TTPAL,UTP20,MAGT1,GPS2,DBI,SSNA1,CD81,TMEM131,WDR13,FANCI,PAPOLA,CREM,FANCL,TET3,GLIS2,IL6ST,INTS1,POP7,SLC44A1,MTPN,ASB6,PLK1,RPP25,CELSR2,SEPT9,RBX1,APH1A,RAD51AP1,ZBED5,CKAP2L,PSMG1,UBE2V1,EAF2,IL12RB1,KRTCAP2,LUC7L,LSG1,NECAP2,TRIM4,ALG3,AGPAT2,CHD3,ZNF367,E2F4,PRPF4,KPNA2,BEND6,CLN3,DNAJC30,FAM208A,NGLY1,POT1,MYL12B,CCDC137,RMND5A,HJURP,PHB2,DNAJB2,FAM53C,NKD2,SDC2,KLC1,CDK13,ADCK5,COX4I1,DNAJB1,RAB6A,ARID1B,C1GALT1,MLX,UBE2Q2,CCP110,ZNF746,ARL6IP1,CTR9,NIPSNAP1,ABHD2,DCAF8,ACSL3,LDB1,MAP4K3,ARMC8,RBM38,NMT2,IRF5,HAUS8,MBIP,ORMDL2,COX7A2L,ZDHHC7,SIL1,FAM122A,DTD1,UNC13C,BCCIP,SART1,TRAF7,NDUFAF2,TOR1AIP1,ZNF416,LAGE3,TM9SF3,ZFYVE21,RRAGC,ZNF121,OIP5,NRF1,WDR44,PPME1,PIN1,EFCAB11,RPAP1,CABLES2,LMAN1,AHCYL1,TOP1MT,STRAP,SPSB3,ZNF583,SNX25,ARHGAP17,POLR2G,ZNF780B,PPT1,NUP155,DCLRE1C,MRPS14,RHBDF2,SUGP1,RBL1,FASTK,UBXN2B,STK38,AP1S1,SPRYD4,SLC22A23,H3F3A,CHID1,SMAD4,RAD51D,SLC30A9,UNK,CMAS,NADSYN1,HMGN3,NCAPG,SCYL2,FZD6,HERC3,GTPBP3,CTSS,ORC3,RNLS,YTHDC1,ACP2,HMGN5,CSRP1,METTL5,ABCF2,TUFM,RANGAP1,PNPLA8,HAGH,API5,ZFR,SEC23IP,E2F1,TMEM219,USP20,RBPJ,PDCD6IP,MAX,LUZP1,GXYLT1,ADAM10,CXXC1,TSC22D3,AP3M2,CUL1,GYG1,NANS,OAT,MYEF2,ANKRD26,PA2G4,NOL11,FIZ1,ZNF200,MARCH2,SLC26A2,SRP72,KLF10,LACTB,CBFB,RFC2,RAB2B,PRIM1,MAP3K4,HHEX,LUC7L3,RPS14,MAP4,MRPL27,BTF3,PTPDC1,NMD3,CCDC59,PTOV1,COX5B,DNAJC5,SCOC,DHPS,ANKH,C16orf87,VAV2,PRKAA1,GSPT2,TATDN3,DLGAP4,PXMP2,PRPF39,PSEN1,ZNF79,PDXDC1,VPS25,NDUFS7,YY1AP1,C12orf10,FAM192A,RPN1,LHX8,ARPC5,TPST1,DAPK1,CYC1,SOCS5,FDFT1,PIGT,EMB,WDR1,ZNF574,EXOSC9,ARID1A,PTTG1IP,C9orf40,FXR1,GOSR1,MAP2K2,TWISTNB,AKAP1,XRCC5,HMGN2,PI4K2A,CAT,DERL1,MTHFD2,HSPBP1,CEBPG,ARAP1,USP32,FAM83D,CABIN1,SMPD4,GPI,CYTIP,TP53RK,REPS2,RAB11B,UROD,SLC39A13,BCL2L1,DECR1,RALB,SIAH1,ADCY9,LPIN2,MRPS27,SOCS6,TTC3,RNASEH2A,CFL1,ANKLE2,CDC123,OAF,VDAC2,EDF1,EML4,ERC1,AMZ2,ANKZF1,RAD51C,ZNF282,DSN1,DDOST,HINT1,DGCR8,SAFB,FTSJ1,RWDD4,LMBR1,NCLN,BEND3,EYA2,DYNC1LI2,SLC41A1,MANBA,B4GALT5,TKT,FAM76A,CBLL1,ARGLU1,LANCL1,POFUT1,FAM8A1,HEATR5B,HLA-A,EBP,RFWD3,NDUFA2,FUT8,FJX1,PTPN11,MRPL54,FEM1B,RPL19,CNN2,MTX2,MSH6,PDLIM2,LONRF3,RFXANK,FBXO9,GUF1,RPL32,ZHX1,OAZ2,NDUFS5,WDR91,GPR89B,RORB,POLA2,ZNF76,MTX3,COPA,UQCR10,HMGXB3,PHRF1,ABCB10,COMMD5,MAP1LC3B,DST,SIVA1,RAB35,GPATCH1,TCEA1,DRAM2,DEAF1,TRAPPC13,SNRNP200,NCK1,LAP3,VHL,SREK1,ARHGDIB,PITPNB,BRWD1,PPM1G,SH3GLB2,BAZ1B,CAB39,ACBD4,STK11,CLU,CHEK2,ZSWIM3,TSTD2,MRPL13,CHPT1,DCAF5,CAPN1,UBE2D3,NSMCE4A,PPP1R12A,ZCCHC8,GORASP1,UBXN1,NACA,EPN1,PCSK7,RPL15,THRAP3,TTF1,QSOX2,PRPF18,NUP205,CHKA,DTL,ZRANB1,MCPH1,SLC12A2,ATP6V0D1,CSNK1G3,CREG1,NUDT4,RPL6,SLTM,EVC2,KLHL15,SIAH2,SLC16A1,EHD4,SNRNP70,C11orf1,APOL2,N4BP2L2,SNX27,CORO7,FEZ2,UCK2,PMS2,UCK1,CLCC1,EXT2,MXD1,USP5,HNRNPA2B1,SAP130,NVL,PPP6C,CYB5R1,ZNF770,EBAG9,RNF25,PCGF6,METTL2A,PON2,HNRNPR,HPS5,STAT6,MAPK1,BRD9,TMEM33,NAT14,DNAJC2,TRIP12,SHPRH,SCYL1,VPS45,MYO9B,GFM2,SPPL2A,FASTKD3,FGFR3,PPIG,ZDHHC13,TMEM99,H2AFY,ATG13,NDUFS8,ERI3,FBL,FRMD8,SLC35A1,MICAL3,TGFB1,B3GALT6,ELOVL5,HEMK1,TIMMDC1,HELB,PSPC1,MIER1,SCFD2,NDRG3,CDK11A,MTMR3,MEGF9,ACAT1,CENPT,PLOD3,RAB3IL1,RAB14,ADD1,MRPS15,KDM4A,XIAP,DHX8,GLUD1,PABPC4,CALM2,CDK5,PSMD1,NEK6,NSRP1,RABGAP1L,SRSF4,FNIP2,KCNAB2,PCBP2,MLST8,PLK3,ZNF672,MRPL43,HSDL1,TOPORS,MCL1,SMC2,PPFIA3,ICMT,SLC50A1,STOML2,LIMK1,ZNF689,PRDX5,ATE1,MLYCD,ATP6V0C,ST3GAL2,FBXL3,TFDP2,E2F2,PFKP,AAAS,DDX42,SSRP1,MRPL9,MRPS2,STRN4,TOP2B,ZNRF3,TMED3,DDRGK1,RAVER2,GNS,INTS7,INPP5A,MCM5,PHF14,ZNF326,NAGPA,ETV3,TSPYL4,TSPAN31,DHX29,TEX10,MAN1B1,CBFA2T2,ABCF1,RHOB,LRRC14B,DTWD1,PTPRF,SCARB2,OSBPL11,CCDC86,DUSP3,SLAIN1,MDH1,HEXA,RNF139,SNX14,ZNF296,TRERF1,UBR2,CHD1L,ACTR3,WDTC1,MYH9,CREBL2,NIPA2,PRKACA,SAFB2,ANKIB1,STAM,ARL6IP6,RAB21,SP100,ZKSCAN1,DDA1,NUP107,ANKRD13C,MAVS,CEP63,RBM15,ATF2,DCTN1,SHOC2,PSRC1,MAP4K4,WBP2,ATP6V0A1,NUSAP1,DNAJA1,TAZ,C19orf54,TAF2,SEC61A1,WDR7,CBLN2,FUS,GEN1,LRP8,COIL,LRCH1,GALK1,ZNF786,RPS2,SESTD1,TRAK1,JMJD6,SIKE1,AKT1S1,KRI1,FBXO3,ERH,GATC,NDUFB4,PPP1R8,PRDM4,GTSE1,GEMIN6,DCP1A,SGCB,S100A6,IMPA2,NUDC,PDPK1,TK1,GUK1,TNFAIP3,GALC,ZNF512,KIAA0930,MRPS10,DDX39A,RPA1,ZNF862,ZNF180,KEAP1,POLE,TATDN2,PITX1,CAPN7,LRPPRC,PML,HMGB2,USF2,ANAPC4,SRM,DDX47,MCCC1,CDC42SE2,S1PR2,CDIPT,SEC16A,SSR1,LIN9,PCNA,ZNF639,TRMU,PIK3R2,ETV6,PPCDC,TXLNA,FAM86C1,MYBL1,MRPL32,CCAR1,ABCC5,PBXIP1,BAZ2A,TLK1,MRPL12,EZR,LNX2,LRP5,BRCA1,PRKRA,STX16,EPB41,OPTN,SEPT1,SOCS4,QRSL1,PIEZO1,OSGEPL1,GLCCI1,NUDT11,NAA60,GEMIN7,SEPHS2,LZTR1,RACGAP1,PPP3CB,B4GALT4,RLF,RAPGEF6,RB1,VASP,MED8,VMP1,PPIL2,MEA1,TIMELESS,AHDC1,ALDH18A1,TMEM8A,ABCC1,PREB,TRAPPC9,AACS,MEMO1,KRAS,RTF1,UBE4B,NFATC2IP,LY6E,ARPC1A,ZNF174,PSMC4,GOLGA4,PALB2,SYNCRIP,PRPS2,NIPA1,TIGD2,RNF114,FOXM1,MRPL39,XAB2,SUMO2,DUSP22,COMMD8,RPL11,CSDE1,MDM2,CORO1A,METTL9,MINPP1,POC5,DVL2,GM2A,PSMA8,COQ10B,CPOX,TIGD5,SLC26A6,CYP20A1,PRPF3,TXNL4A,RPSA,SRSF1,DNAJC10,ZNF700,SCAP,PLEKHG4B,TIMM17A,FAU,LTA4H,AP2S1,USP53,INTS2,CTDP1,MIF4GD,CDT1,ARID5A,SUMF1,GGA2,AP3S1,CSNK1A1,RMI1,TFRC,PTPN2,IRF4,GSTK1,NDUFV1,SLC1A4,CWC27,SLC35B4,DDX31,ABCD1,RPAP3,CNTN5,SNX2,ZMYM5,CHCHD6,BSDC1,KPNA4,FBXO41,BIRC5,TFE3,SNAP29,CDCA7L,PKD2,ACADM,CHMP7,SAT2,GCSH,ZNF496,TMEM109,TAP1,YTHDF3,NHLRC3,IKBIP,ELMOD2,KIFC1,DBNDD1,CYB5RL,PARPBP,CDC25B,PRADC1,DNMT1,NOL12,ORAI2,USO1,AKT2,NOL8,GNG7,AURKB,MCFD2,SLC25A5,ZFAND5,MAK16,STT3A,TMED10,EIF2D,ITGB1,PTPN7,UQCRH,RRS1,ARRB2,RTN3,ZNF598,DDX58,WSB2,PPIB,MUT,GMFG,HLA-E,NDUFA4,MAN2B1,METTL3,CFLAR,NDUFS4,RNF121,MEX3C,KLF16,HDAC7,DAD1,BDH1,PCYT2,GNAI2,ANKHD1,MORC3,TERF2,KCTD20,SEPT8,DCTD,PKM,TOMM40,PATL1,ADSS,SERTAD2,ZFP92,DCK,ERGIC3,ACLY,LPCAT4,VCPIP1,YY1,PPP6R3,PPP6R2,MAP3K5,RNF14,CDK2,ZC3HAV1,SYS1,ZBTB37,URB2,EIF3D,MAGED1,KLHL18,ADPGK,SLC25A44,AP1B1,SDHA,PAIP2,PHC2,CRKL,TERF2IP,MOAP1,CYHR1,ZNF75D,SHC1,UCHL5,NAA35,TMBIM1,CCT2,CDKN2AIP,MKLN1,HMGN4,LYRM1,GALK2,CDC23,SHCBP1,AP4E1,PRDM11,VEZF1,PPP2R5A,ACYP1,STAT1,PPA2,TRIM32,RHEBL1,R3HCC1L,C1orf112,TCF3,MRI1,BRAP,AGPAT3,MYNN,SDF2L1,SPR,RAB11A,REEP5,FOXO3,MAD2L2,CCDC28A,PIP5K1C,RBM17,MAT2B,PTEN,CENPJ,TAGLN2,OSTC,PACS2,NCOA2,SMC4,RNASEH2C,NEK7,NET1,PARP4,TBRG4,ANAPC2,RPL27A,YIF1A,SGSH,HGS,TTLL4,SLC38A7,MFAP1,CCDC69,BRWD3,ESYT2,SKA3,NPHP4,UBE2E2,HNRNPAB,PLXNC1,ST13,TMEM184B,DNAJC24,ZNF107,SLC29A1,KIF2C,AGFG1,SIRT2,FKBP2,USP48,UBQLN2,SNRPD3,CUTC,EDC3,UBLCP1,ZNF804A,RAP1A,THADA,EIF4A3,AP3S2,ATG3,DPYSL2,PPP1R12C,AKR1B1,NDUFB9,RP2,TTC4,TECR,ARID4A,FGFR1OP2,TIMM50,TDP1,DPM1,FOPNL,SLC16A7,WDR82,STK17B,DHX15,CHAF1A,GEMIN5,COPS6,SASS6,RPS26,PSMC1,SLC12A7,TBC1D12,TM9SF4,ZNF768,UFC1,MED13L,TIA1,MEF2A,EPHX2,PITHD1,RHBDD1,NFATC3,BANF1,ZNF335,BUD31,YBX1,KNTC1,ACAD8,UBE3C,ZNF189,ALDH9A1,KDELR1,TSTA3,CIC,OXR1,PSMA1,SEPT7,NAP1L1,NSMF,ODF2,EXOC4,KIAA1328,NUP62,PITPNA,PTDSS1,PDSS2,C7orf26,TMEM106C,IMMT,ASH1L,CHERP,WDYHV1,PLAGL2,CHKB,IRF3,TWF2,PAIP1,ANKRD28,ANKLE1,FARSA,SAR1A,SCAMP4,APOOL,PDIA6,ACSL5,TOR1AIP2,AZI2,GFER,RAD54B,DAP3,TMEM41A,ZNF317,GADD45B,AKNA,REEP4,CBX4,KIF3B,GOLPH3L,SH2D3A,CASP6,TOR3A,SRGN,DBF4,MFSD10,SAC3D1,CTNNBL1,YIF1B,CLDND1,TTC17,SLC25A1,GINS1,PAQR6,CSNK1G2,TELO2,ADAM17,HMGN1,NASP,ASPM,PPP1R21,PRKAR1B,SYMPK,TARS,SNRPA,MAPK3,HLA-B,ATAD2,PLAA,ZNF330,OSBPL8,KBTBD7,PREPL |
| 3.309e-03 | -5.71 | FGFR2 alternative splicing | REACTOME pathways | R-HSA-6803529 | 28 | 11 | 10287 | 1696 |
POLR2I,POLR2G,POLR2L,POLR2J,POLR2K,POLR2D,HNRNPF,TIA1,HNRNPM,POLR2A,GTF2F1 |
| 3.309e-03 | -5.71 | Energy dependent regulation of mTOR by LKB1-AMPK | REACTOME pathways | R-HSA-380972 | 28 | 11 | 10287 | 1696 |
TSC1,PRKAB1,TSC2,PRKAA1,LAMTOR4,LAMTOR3,CAB39,RRAGC,STK11,RHEB,MLST8 |
| 3.311e-03 | -5.71 | Signaling by BRAF and RAF fusions | REACTOME pathways | R-HSA-6802952 | 61 | 19 | 10287 | 1696 |
AGGF1,NRAS,AGTRAP,RAF1,TRAK1,KRAS,SND1,FXR1,MACF1,MAP2K2,LMNA,MAPK3,RAP1A,CSK,CLCN6,MAPK1,ARRB2,HRAS,ZC3HAV1 |
| 3.311e-03 | -5.71 | The role of GTSE1 in G2/M progression after G2 checkpoint | REACTOME pathways | R-HSA-8852276 | 61 | 19 | 10287 | 1696 |
PLK1,MAPRE1,PSMA8,PSMB7,PSMA1,CCNB1,PSMB9,PSMD9,PSMB3,PSMC4,PSMD2,PSMA6,PSMD1,RPS27A,PSMD3,PSMD8,GTSE1,CCNB2,PSMC1 |
| 3.311e-03 | -5.71 | Ribosomal scanning and start codon recognition | REACTOME pathways | R-HSA-72702 | 61 | 19 | 10287 | 1696 |
RPS15,EIF3L,RPS2,EIF3D,RPS10,RPS24,EIF4H,EIF3G,RPS9,RPSA,EIF3H,EIF3A,EIF3K,EIF2S2,RPS27A,RPS14,EIF5,FAU,RPS26 |
| 3.314e-03 | -5.71 | GO_MEMBRANE_PROTEIN_COMPLEX | MSigDB lists | GO_MEMBRANE_PROTEIN_COMPLEX | 951 | 174 | 17377 | 2626 |
TMED7,COPA,NDUFB6,UQCR10,TAP1,AP3M2,BECN1,SYNRG,BIRC2,PARK7,CALM2,NAPG,TIMM23,AP3S2,IL6ST,PIK3R2,AP1M1,AP2B1,NDUFB9,SPTSSA,KCNAB2,TIMM50,BAK1,SGCE,GNG7,LRP5,IL12RB1,KRTCAP2,STX16,FOXRED1,STOML2,NECAP2,STT3A,TMED10,ITGB1,COX5A,ATP6V0C,VPS4A,TRAF5,ATP6V0E1,SVIP,NDUFV2,GGA1,HLA-E,UBXN1,LAMTOR3,NDUFA4,COX4I1,TMED3,PSEN1,ITGB5,VPS25,COPG2,NDUFS7,COPB2,NPLOC4,NDUFS4,CFLAR,RPN1,DAD1,ARL6IP1,ATP6V0A2,BCL2,GNAI2,ATP6V0D1,PIGT,SYVN1,TOMM40,GOSR1,FAS,SEC31A,DERL1,GNAS,SDHB,SNAP23,NUP62,MAP3K5,RNF139,NDUFA5,SNX27,CHMP2A,IMMT,TOMM20,COPE,VTI1A,RRAGC,MYH9,CLCC1,AP1B1,ATP6V1B2,LYN,PRKACA,SDHA,BCAP31,EXT2,ATP6V0B,SHC1,ATP2A2,TAP2,RPN2,APOOL,CLTB,GM2A,HTRA2,ATP6V1G1,DCTN1,PPIF,SNX8,SEC61B,RAB7A,SLC26A6,VDAC2,LRRC8A,ATP6V0A1,NDUFA7,CHMP2B,VDAC1,NDUFB1,AP4E1,TOLLIP,CHCHD3,ANKZF1,CHMP4A,ATP1A1,DDOST,VPS26B,TOMM6,TIMM17A,CORO1C,NDUFA11,SEL1L,AP1S1,CHMP4B,AP2S1,NDUFS1,SESTD1,SCYL1,FLOT1,SDF2L1,GGA2,AP3S1,TFRC,HLA-A,NDUFV1,CLIC4,ITGB8,NDUFA2,NDUFB4,SEC24C,NDUFS8,OSTC,SGCB,NDUFA3,RNF5,SNX2,ABCF2,KCNQ1,CHCHD6,PICALM,FADD,HLA-B,GNA12,CACNB1,ATP6V1D,MAGT1,SNAP29,STX18,COX8A,SPCS3,NDUFS5,ATP6V1C1,CHMP7,VPS29,FAF1 |
| 3.317e-03 | -5.71 | GSE32255_WT_VS_JMJD2D_KNOCKDOWN_4H_LPS_STIM_DC_DN | MSigDB lists | GSE32255_WT_VS_JMJD2D_KNOCKDOWN_4H_LPS_STIM_DC_DN | 136 | 33 | 17377 | 2626 |
SEPHS2,H2AFZ,NOP2,SUCLG1,WDR13,MDH2,VPS45,FKBP2,NDUFS4,HOMER1,MEX3C,ATIC,DAPK1,SLC12A2,PPA1,FDFT1,RBM15B,TDP1,DDX24,RDH10,TOPORS,BUD13,TRIM28,STOML2,YIF1A,TPD52L2,PALB2,RPS27A,HNRNPH3,TBL3,SH3GLB2,ASNA1,SMAD1 |
| 3.320e-03 | -5.71 | TatD_DNase | pfam domains | PF01026 | 3 | 3 | 17054 | 2545 |
TATDN1,TATDN2,TATDN3 |
| 3.320e-03 | -5.71 | CK1gamma_C | pfam domains | PF12605 | 3 | 3 | 17054 | 2545 |
CSNK1G2,CSNK1G1,CSNK1G3 |
| 3.320e-03 | -5.71 | SAPS | pfam domains | PF04499 | 3 | 3 | 17054 | 2545 |
PPP6R2,PPP6R3,PPP6R1 |
| 3.320e-03 | -5.71 | CSN8_PSD8_EIF3K | pfam domains | PF10075 | 3 | 3 | 17054 | 2545 |
EIF3K,COPS8,PSMD8 |
| 3.320e-03 | -5.71 | Tom37 | pfam domains | PF10568 | 3 | 3 | 17054 | 2545 |
MTX1,MTX3,MTX2 |
| 3.320e-03 | -5.71 | CDC25C (cell division cycle 25C) | protein interactions | 995 | 108 | 29 | 17029 | 2761 |
PLK3,PLK1,NF1,DENND4C,GLO1,BRCA1,CCNB1,MAPK14,GIGYF1,MAPK3,RTKN,CDK5,ZBTB21,PCNA,HSPBP1,CCNA2,HSPA4,SHC1,RPS27A,PIN1,KIF13B,YWHAZ,CHEK2,CDK2,MAPK1,CCNB2,YWHAH,HRAS,CDC37 |
| 3.320e-03 | -5.71 | MORF4L1 (mortality factor 4 like 1) | protein interactions | 10933 | 108 | 29 | 17029 | 2761 |
TRIM41,ZBTB10,ASH1L,H2AFZ,PBXIP1,DNAJB2,RACGAP1,GMCL1,BRCA1,MPG,H2AFV,APP,MEAF6,LMNA,RB1,KPNA1,HSPA4,PALB2,SYNCRIP,GOLGA2,HNRNPR,L3MBTL3,MRFAP1L1,ACTB,RUVBL2,MSH6,HNRNPM,HDAC2,CDC5L |
| 3.320e-03 | -5.71 | E2F4 (E2F transcription factor 4) | protein interactions | 1874 | 108 | 29 | 17029 | 2761 |
CHMP2A,NCOR2,RECQL,KAT2A,PBK,MYBL2,CDC6,BRCA1,TRIM28,JMY,LIN9,RB1,SMAD2,PCM1,CCNA2,ATAD2,BIRC5,RBL1,AP3S2,MFAP1,TFDP1,PML,MSH2,E2F1,TP53BP2,TFDP2,CDK2,E2F2,RYBP |
| 3.320e-03 | -5.71 | POLR2C (RNA polymerase II subunit C) | protein interactions | 5432 | 108 | 29 | 17029 | 2761 |
CTDP1,DNMT3A,POLR2I,POLR2G,POLR2L,POLR2K,MTA2,ELOA,CUL3,POLR2D,KLC1,BRCA1,PSMB9,RPS9,DHX15,POLR2A,GTF2F1,WWP2,MED10,POLR2J,HNRNPR,MAP4,PPP4R1,ZNF326,RPAP1,CTR9,INTS12,TCEA1,RPRD1B |
| 3.323e-03 | -5.71 | WANG_CLIM2_TARGETS_UP | MSigDB lists | WANG_CLIM2_TARGETS_UP | 216 | 48 | 17377 | 2626 |
OTUD5,NADSYN1,REPS2,ZCCHC8,ARID2,CDT1,BCL2L1,GGA2,SLC12A9,C19orf48,GFM2,RAVER2,NFATC3,PPIL2,PDS5B,FBXW2,ATG13,MAVS,SLC26A2,LMAN1,CHTOP,SMC4,TRIM8,ETV3,CIC,DENND1B,MRS2,CIRBP,RTF1,RANGAP1,OTUD3,DIDO1,SRSF5,SERP1,ZMYM3,KRIT1,PTPRF,DNAJC10,TFDP1,MAP4,ARAP1,BTF3,PPP6R3,NR2F2,ARRB2,E2F2,CCDC59,GPATCH4 |
| 3.328e-03 | -5.71 | Endocrine resistance | KEGG pathways | ko01522 | 95 | 26 | 7161 | 1149 |
NRAS,AKT2,RAF1,E2F3,KRAS,NOTCH2,MAPK14,PRKACA,MAP2K2,MAPK3,GNAS,CDKN2C,RB1,MDM2,SHC1,ADCY9,PIK3R2,E2F1,CDKN1B,BCL2,MAPK1,E2F2,HRAS,CDKN2A,CARM1,ADCY7 |
| 3.328e-03 | -5.71 | Endocrine resistance | KEGG pathways | hsa01522 | 95 | 26 | 7161 | 1149 |
NRAS,AKT2,RAF1,E2F3,KRAS,NOTCH2,MAPK14,PRKACA,MAP2K2,MAPK3,GNAS,CDKN2C,RB1,MDM2,SHC1,ADCY9,PIK3R2,E2F1,CDKN1B,BCL2,MAPK1,E2F2,HRAS,CDKN2A,CARM1,ADCY7 |
| 3.334e-03 | -5.70 | IMMT (inner membrane mitochondrial protein) | protein interactions | 10989 | 137 | 35 | 17029 | 2761 |
COX15,IMMT,HJURP,SUZ12,TCF3,MYH9,SLC25A12,NDUFA4,ADCK5,SRRT,NDUFB9,KIF22,APOOL,ATF2,MTX2,SLC25A1,CDC37,HP1BP3,UBQLN4,TK1,PRRC2A,RAB7A,VDAC2,ATXN1,ADRB2,VDAC1,TOMM40,CHD3,HNRNPR,KPNA2,ATP5F1A,CLN3,CD81,FUBP1,SNAPIN |
| 3.340e-03 | -5.70 | cytoplasmic side of membrane | cellular component | GO:0098562 | 198 | 44 | 18223 | 2701 |
PKP4,CYLD,NF1,CDIP1,RACGAP1,RGS2,LYN,MIEN1,BIRC2,RGS1,SPPL2A,ABL2,FKBP1A,RAB21,ATP2A2,THADA,SNX18,PTEN,GNAI2,GM2A,S100A6,HTRA2,KCNAB2,PPP3CA,CYTH1,RHOA,GNG7,EZR,KRAS,DNAJA1,MAP2K2,SPPL2B,EPB41,GNAS,GNA12,CHMP4A,JAK1,CSK,PTPN7,PKD2,CHMP4B,TRAF5,RPS26,ESYT2 |
| 3.342e-03 | -5.70 | mixed_adenosquamous_carcinoma | COSMIC cancer mutations | mixed_adenosquamous_carcinoma | 112 | 28 | 17385 | 2587 |
DCAF6,MAX,DNMT3A,NRAS,ATG9A,VHL,SF3B1,SMARCA4,KLC1,KRAS,KMT2C,EML4,HEATR5B,GNAS,KIF5B,FGFR3,HLA-B,RB1,PTEN,CCDC6,ATIC,PTPN11,STK11,TFG,ASB6,HRAS,SMAD4,CDKN2A |
| 3.345e-03 | -5.70 | GSE21546_WT_VS_SAP1A_KO_ANTI_CD3_STIM_DP_THYMOCYTES_DN | MSigDB lists | GSE21546_WT_VS_SAP1A_KO_ANTI_CD3_STIM_DP_THYMOCYTES_DN | 189 | 43 | 17377 | 2626 |
ZNF207,PIGM,ASH1L,FOXM1,KDM4A,GORASP1,SHPRH,TOR3A,HNRNPUL2,TMX4,KLHL18,CUL1,TMEM165,METTL3,CRKL,PTPN2,MRPL50,STARD9,ZNF473,SLC1A4,TNFAIP8,CENPJ,TAP2,FBXL19,SCYL3,CCAR1,ABCC1,MLST8,USP34,CPNE1,HSDL1,TAZ,FADD,RHBDF2,IWS1,MKNK1,WDR11,EXOC4,H2AFX,USP32,ARRDC1,GEN1,POT1 |
| 3.345e-03 | -5.70 | GSE17721_POLYIC_VS_CPG_6H_BMDC_UP | MSigDB lists | GSE17721_POLYIC_VS_CPG_6H_BMDC_UP | 189 | 43 | 17377 | 2626 |
DNMT3A,MRPL39,FAM53C,HEXB,UCK2,RRAGC,CHIC2,ARGLU1,HAUS4,CNTROB,REEP5,ANKIB1,BIRC2,LMNA,PIP5K1C,HOMER1,DNAJC8,MTMR4,EI24,CDKN1B,RP2,TALDO1,MVP,CTDSP2,CAMK2G,MORC3,SNX2,PSMG1,RAB3IP,HERPUD2,PLEKHF2,EPB41,MKNK1,CORO1C,MAFK,NFIL3,U2SURP,COX7A2L,ACADM,BRWD3,TOB1,CSNK1D,SNAPIN |
| 3.345e-03 | -5.70 | GSE17721_LPS_VS_POLYIC_8H_BMDC_DN | MSigDB lists | GSE17721_LPS_VS_POLYIC_8H_BMDC_DN | 189 | 43 | 17377 | 2626 |
ZCCHC8,DAP,TSC22D3,HNRNPUL2,MYO9B,MXD4,IL21R,FOXO3,MBD4,HOMER1,ATG3,SOCS6,BRI3,INTS12,CYC1,TIPARP,TMEM14C,ALDH9A1,LARS,CYTH1,AGGF1,PTPN18,BIRC3,PRKDC,LDHA,TOP3A,SEPT8,ISG15,ECH1,RPSA,GLOD4,MYO1F,MKNK1,SCARB2,FAM3C,ACADM,FBXL3,SMAD4,PURA,TOB1,LRP8,SLC25A39,FAF1 |
| 3.345e-03 | -5.70 | GSE3982_DC_VS_BASOPHIL_DN | MSigDB lists | GSE3982_DC_VS_BASOPHIL_DN | 189 | 43 | 17377 | 2626 |
WASF2,GLT8D1,CYLD,REPS2,MANBA,RAF1,SRSF6,MED13L,BRAP,CTCF,RLF,MAP1LC3B,FAM8A1,GIT2,C2orf68,SLC25A36,PCYOX1L,TERF2IP,SRSF4,ZDHHC13,INTS12,BRD7,CEP63,CTDSP2,RHOA,SELPLG,RPL6,PRPF3,DIDO1,PRMT2,ZDHHC3,ARHGAP15,C22orf46,RPL36,RPL37,PPP2R5A,ETS2,STK38,SIAH2,TRIM52,H3F3A,CHPT1,S100PBP |
| 3.345e-03 | -5.70 | GSE5960_TH1_VS_ANERGIC_TH1_UP | MSigDB lists | GSE5960_TH1_VS_ANERGIC_TH1_UP | 189 | 43 | 17377 | 2626 |
GNPNAT1,COPE,GADD45G,SDC2,MRPS26,EBNA1BP2,SUB1,RAP1A,NDUFA2,ZNF639,SUCLG2,MRPL40,AQR,SMARCE1,ZNRD1,SEH1L,ZNF524,DEAF1,RFC3,EID1,PPT1,PSMA1,PSMG1,ANAPC2,MTX1,C9orf40,RPSA,RPA1,SEC31A,PON2,EPRS,SLC19A1,CCDC86,ZHX1,QARS,CDCA7L,IMPDH1,ZFP90,SNRPG,PPP5C,COIL,ADAM23,DDX52 |
| 3.345e-03 | -5.70 | GSE17721_PAM3CSK4_VS_CPG_24H_BMDC_DN | MSigDB lists | GSE17721_PAM3CSK4_VS_CPG_24H_BMDC_DN | 189 | 43 | 17377 | 2626 |
PDCD6IP,CDS2,SYS1,TRIP12,COPA,AGRN,TOR3A,DLGAP4,NIPA2,AGFG1,PPP3CB,TWF2,REEP5,HNRNPA2B1,KIF5B,MDM2,VMP1,TIMM23,SSBP3,CREB1,CYFIP1,TRAFD1,MAPRE2,ZFP64,RBM42,PGS1,WDR1,LACTB,MRPL12,TOR1AIP2,WDR82,MCL1,ABCF1,ORMDL2,CCDC86,DCK,GADD45B,TMEM219,PITPNA,PSAP,CD81,TAF6,LONP2 |
| 3.345e-03 | -5.70 | GSE15330_GRANULOCYTE_MONOCYTE_PROGENITOR_VS_PRO_BCELL_DN | MSigDB lists | GSE15330_GRANULOCYTE_MONOCYTE_PROGENITOR_VS_PRO_BCELL_DN | 189 | 43 | 17377 | 2626 |
KRBA1,SLC41A1,FAM53C,MYO9B,CMTM6,PIP5K1C,C14orf119,FBRS,KIF5B,USF1,PRKD3,NFATC3,CRAT,SLC44A1,SRI,ABCD1,GLTP,BCL2,UBE3B,F2R,S100A6,RYBP,ARHGAP17,KIAA0930,WBP2,ILF3,ARHGDIB,DNAJA1,SYVN1,SMAP2,TFEB,PPP2CA,PON2,ATP6V1D,TTC13,GRIPAP1,GPS2,ACOX1,GADD45B,OAZ2,CNOT6,CPEB2,ANXA11 |
| 3.345e-03 | -5.70 | GSE17721_POLYIC_VS_CPG_24H_BMDC_UP | MSigDB lists | GSE17721_POLYIC_VS_CPG_24H_BMDC_UP | 189 | 43 | 17377 | 2626 |
DNMT3A,SYS1,ZNF768,RHOC,CTCF,COX4I1,SECISBP2,THRAP3,SNN,CRKL,SUB1,CLIC4,ADD3,AFF1,MAP3K14,CNOT6L,GTF2H2,PABPC1,PDPK1,CSNK1G2,ZNF524,RBM42,GUK1,ERF,VDAC2,SLC25A22,UBE2V1,PRPSAP1,PLD3,PDCD6,CCDC6,GPS2,MFAP1,NAGLU,NFIL3,ARRDC1,TMEM219,ACTB,CHMP4B,SLC22A23,USF2,MYL12B,TMEM131 |
| 3.345e-03 | -5.70 | GSE23502_WT_VS_HDC_KO_MYELOID_DERIVED_SUPPRESSOR_CELL_BM_UP | MSigDB lists | GSE23502_WT_VS_HDC_KO_MYELOID_DERIVED_SUPPRESSOR_CELL_BM_UP | 189 | 43 | 17377 | 2626 |
ZNF207,FGFR1OP,GGNBP2,PKP4,PTTG1,HEXB,ACAP1,SMC6,CREBL2,TOP2B,NOTCH2,MXD4,DOCK11,ETS1,FOXO3,ARID1B,SLC25A37,UBLCP1,PAIP2,MBD4,TNS3,MTMR4,TBC1D14,LPIN2,LDLRAD3,ARID4A,GM2A,CSNK1G3,CADM1,ARID1A,SOX4,POLG2,FKBP3,CBX3,HLA-B,BRWD1,HNRNPH3,CAMKMT,SLAIN1,TRAF5,ACSF2,ANAPC4,PRPF4B |
| 3.349e-03 | -5.70 | septin cytoskeleton | cellular component | GO:0032156 | 15 | 7 | 18223 | 2701 |
SEPT11,TMEM250,SEPT8,SEPT1,SEPT9,SEPT7,MAPK6 |
| 3.349e-03 | -5.70 | COPI vesicle coat | cellular component | GO:0030126 | 15 | 7 | 18223 | 2701 |
TMED7,TMED3,COPA,COPG2,COPE,SCYL1,COPB2 |
| 3.351e-03 | -5.70 | Casein_kinase-1_gamma_C | interpro domains | IPR022247 | 3 | 3 | 18492 | 2768 |
CSNK1G2,CSNK1G1,CSNK1G3 |
| 3.351e-03 | -5.70 | TatD_family | interpro domains | IPR001130 | 3 | 3 | 18492 | 2768 |
TATDN1,TATDN2,TATDN3 |
| 3.351e-03 | -5.70 | CSN8_PSD8_EIF3K | interpro domains | IPR033464 | 3 | 3 | 18492 | 2768 |
COPS8,EIF3K,PSMD8 |
| 3.351e-03 | -5.70 | SAPS | interpro domains | IPR007587 | 3 | 3 | 18492 | 2768 |
PPP6R2,PPP6R3,PPP6R1 |
| 3.351e-03 | -5.70 | rRNA-MeTfrase_E | interpro domains | IPR015507 | 3 | 3 | 18492 | 2768 |
FTSJ3,FTSJ1,MRM2 |
| 3.351e-03 | -5.70 | Hex-like_dom2 | interpro domains | IPR029018 | 3 | 3 | 18492 | 2768 |
HEXA,NAGLU,HEXB |
| 3.351e-03 | -5.70 | DNA-dir_RNA_pol-M_15_CS | interpro domains | IPR019761 | 3 | 3 | 18492 | 2768 |
POLR2I,ZNRD1,POLR3K |
| 3.351e-03 | -5.70 | Sam37/metaxin_N | interpro domains | IPR019564 | 3 | 3 | 18492 | 2768 |
MTX1,MTX3,MTX2 |
| 3.351e-03 | -5.70 | Rpa12/Rpb9/Rpc10/TFS | interpro domains | IPR012164 | 3 | 3 | 18492 | 2768 |
POLR2I,ZNRD1,POLR3K |
| 3.357e-03 | -5.70 | MFAP1 (microfibril associated protein 1) | protein interactions | 4236 | 80 | 23 | 17029 | 2761 |
SART1,CCDC57,ZFP64,EWSR1,SUZ12,SMU1,DHX8,DDX20,CSNK2A1,JMJD6,EIF2AK1,PRPF3,LMNA,PHC2,RPL37,GOLGA2,E2F4,CDCA7L,U2SURP,CEP55,E2F1,CDK2,COIL |
| 3.357e-03 | -5.70 | ARPC3 (actin related protein 2/3 complex subunit 3) | protein interactions | 10094 | 80 | 23 | 17029 | 2761 |
WASF2,OTUD5,ACTR3,EZR,MYH9,KRAS,CAPZA2,ANLN,ARPC1A,PRKACA,PTPRF,CEP104,VASP,WAS,GOLGA2,ARPC5,MYO18A,MAPK6,EFTUD2,CAPZA1,ARAP1,LTA4H,PITRM1 |
| 3.357e-03 | -5.70 | DDX27 (DEAD-box helicase 27) | protein interactions | 55661 | 80 | 23 | 17029 | 2761 |
NOL12,SRP72,PPAN,NIFK,STAU1,RRP15,DDX24,RPL8,API5,MAK16,KRR1,LYAR,SYNCRIP,DGCR8,RBM34,MCM5,ZNF746,FBL,ARRB2,FTSJ3,ZC3HAV1,IFI16,GPATCH4 |
| 3.357e-03 | -5.70 | ADGRG5 (adhesion G protein-coupled receptor G5) | protein interactions | 221188 | 80 | 23 | 17029 | 2761 |
TMED7,PIGM,ACP2,TMUB1,ABCA3,SIGMAR1,TMX4,ATP6V0A1,SLC29A1,EDEM2,SLC12A9,LCLAT1,SPPL2B,ABHD14A,FZD6,ASPHD2,NUS1,OSBPL8,ERGIC3,ATP13A3,FAM3C,MIA2,SRPK2 |
| 3.368e-03 | -5.69 | GSE19888_ADENOSINE_A3R_INH_VS_ACT_IN_MAST_CELL_UP | MSigDB lists | GSE19888_ADENOSINE_A3R_INH_VS_ACT_IN_MAST_CELL_UP | 173 | 40 | 17377 | 2626 |
SEPHS2,TCF12,EXOC3,MMACHC,IER2,PTMS,FGFR1OP,HJURP,MRPS2,DNAJB2,LANCL1,SND1,TFRC,FBRS,CYHR1,C18orf32,GMEB1,PRC1,H2AFY,NAP1L4,PRADC1,NDUFA3,POC5,CSNK1G2,TSPAN31,NLN,RHBDF2,EIF4ENIF1,ATAD2,TMEM54,DUS3L,NSF,SNAP29,GADD45B,EIF2D,SAMD8,BEND3,MAPK1,ZNF598,HRAS |
| 3.368e-03 | -5.69 | GSE17974_0H_VS_2H_IN_VITRO_ACT_CD4_TCELL_DN | MSigDB lists | GSE17974_0H_VS_2H_IN_VITRO_ACT_CD4_TCELL_DN | 173 | 40 | 17377 | 2626 |
PIGM,GNPNAT1,PHF23,ADO,TRMT6,ZNF416,BRIX1,TMEM165,GLRX3,WRB,KTN1,PNO1,FBXO22,COPB2,C14orf119,LYAR,IRF4,VASP,VMP1,TXLNA,GEMIN6,ORAI1,ARHGEF2,LYPLA2,ZNF583,KLF10,ERLIN1,CRNKL1,SLC17A5,FADD,MTHFD2,OSBPL11,TIMM13,C1orf109,DNAJC17,MLYCD,SLC25A19,CPEB2,FAM83G,ZSWIM6 |
| 3.384e-03 | -5.69 | ATP6V1E1 (ATPase H+ transporting V1 subunit E1) | protein interactions | 529 | 62 | 19 | 17029 | 2761 |
PPIF,SCAMP3,LAMTOR3,ATP6V0A1,COX4I1,ATP6V1B2,PICALM,APP,ZFR,SUGP1,ATP6V1D,ATP6V0A2,YBX1,CHMP4B,NDUFS8,SRSF3,ATP6V1C1,ATP6V0E1,ATP6V1G1 |
| 3.384e-03 | -5.69 | INTS3 (integrator complex subunit 3) | protein interactions | 65123 | 62 | 19 | 17029 | 2761 |
INTS2,CTDP1,POLR2G,INTS13,POLR2D,CAPZA2,APP,POLR2A,RPA1,RPA2,POLR2J,INTS7,INTS1,NABP1,NABP2,INTS12,RP2,C7orf26,CDC5L |
| 3.384e-03 | -5.69 | FIP1L1 (factor interacting with PAPOLA and CPSF1) | protein interactions | 81608 | 62 | 19 | 17029 | 2761 |
STAU1,POLK,SUZ12,RNPS1,CSNK2A1,PRMT2,SEC16A,SYMPK,APP,PAPOLA,WWP2,KIF2A,GOLGA2,CDCA5,PML,NUP153,CPSF4,CSTF1,SRPK2 |
| 3.387e-03 | -5.69 | MAPK1 (mitogen-activated protein kinase 1) | protein interactions | 5594 | 311 | 69 | 17029 | 2761 |
KARS,PDCD6IP,TSC2,RPS6KA1,RAF1,PTTG1,CSNK2A1,MAPK14,VAV1,SHC1,NUP153,ATF2,MTPN,ILKAP,PLK3,ERF,GMFB,RRM2,MCL1,BRCA1,SUPT20H,VDAC1,MCM2,PRPSAP1,PPP2CA,UBTF,MKNK1,SMAD2,ATP1A1,HNRNPR,DGCR8,CEP55,PTPN7,CHEK2,PTPDC1,NCOA1,COPS6,SMAD1,ARRB2,MAPK1,SMAD4,ZC3HC1,TCF3,LAMTOR3,DNAAF5,ETS1,FOXO3,CAPN2,RB1,DAPK1,ARHGEF2,YBX1,BCL2,CITED2,STAT3,PPP1R9B,ADAM17,GORASP2,KRAS,ELK1,PKM,MAP2K2,MAPK3,PTPRF,ATP6V1D,DUSP3,PML,NDE1,TOB1 |
| 3.388e-03 | -5.69 | Notch Signaling Pathway | WikiPathways | WP268 | 46 | 15 | 5312 | 837 |
NCOR2,ADAM17,KAT2A,APH1A,DTX4,MFNG,RBPJ,DVL1,NOTCH2,MAML1,APH1B,PSEN1,DVL2,NUMB,HDAC2 |
| 3.391e-03 | -5.69 | TACTTGA,MIR-26A,MIR-26B | MSigDB lists | TACTTGA,MIR-26A,MIR-26B | 288 | 61 | 17377 | 2626 |
TMEM184B,ARID2,MED13L,YTHDF3,PAWR,PPP3CB,FAM136A,SNN,RLF,CCDC28A,ATPAF1,DLG5,RAP1A,NUS1,NEK6,STRBP,DAPK1,CLDND1,MOB1A,EIF5,ATF2,SLC12A2,FBXL19,MTX2,BAK1,ARHGAP17,ZDHHC18,ABHD2,KLF10,ERLIN1,ACSL3,CAMSAP1,PFKFB3,RTF1,MCL1,UBE4B,C9orf40,CBFB,EIF4G2,PDHX,EIF3A,PHF6,OSBPL11,BRWD1,TTC13,CCDC6,PTER,CSNK1G1,MAPK6,PPP3R1,COX5A,KPNA2,TAF12,SLC22A23,SMAD1,REEP4,SMAD4,TOB1,PURA,ALS2,TMEM33 |
| 3.394e-03 | -5.69 | GO_COATED_VESICLE_MEMBRANE | MSigDB lists | GO_COATED_VESICLE_MEMBRANE | 131 | 32 | 17377 | 2626 |
TMED7,USO1,DNAJC5,COPA,HLA-E,SCYL1,COPE,VTI1A,TMED3,AP1B1,MCFD2,SYNRG,PICALM,COPG2,HLA-A,COPB2,NECAP2,SEC31A,CD59,HLA-B,SEC23IP,TMED10,SCAP,SEC24C,AP1M1,AP1S1,AP2B1,CLTB,LMAN1,AP2S1,TMED2,KDELR1 |
| 3.404e-03 | -5.68 | membrane protein proteolysis | biological process | GO:0033619 | 43 | 14 | 17256 | 2622 |
TGFB1,ADAM17,ADAM10,APH1A,RBMX,MYH9,PARL,ADAM9,YBX1,PSEN1,APH1B,SPPL2B,RHBDD1,SPPL2A |
| 3.407e-03 | -5.68 | UFD1 (ubiquitin recognition factor in ER associated degradation 1) | protein interactions | 7353 | 94 | 26 | 17029 | 2761 |
CHMP2A,ATG9A,SUZ12,RAE1,UBXN1,LDHA,ANAPC2,MTMR12,ADRB2,DHX15,NPLOC4,PAPOLA,PTPRF,PSMD2,BIRC5,HUWE1,TXLNA,RTCB,NSFL1C,VCPIP1,FUS,FAF1,PDCD4,CFL1,SVIP,USP13 |
| 3.417e-03 | -5.68 | V$AHR_Q5 | MSigDB lists | V$AHR_Q5 | 200 | 45 | 17377 | 2626 |
IMMT,NPHP4,MAX,H2AFZ,ZFP91,MECP2,SRSF6,C16orf87,ADO,GADD45G,RAB6A,AP3S1,FOXO3,BZW2,GIT2,CD320,ZNF428,NRF1,KDM2A,FUT8,TTC9C,AXIN2,CDKN1B,ANP32A,FGFR1OP2,PCBP2,CFL1,AMPD2,RHOA,EID1,HSDL1,CIRBP,MBD3,SERP1,EIF3A,DOT1L,SUPT16H,PALB2,CHCHD1,ATXN2L,YWHAZ,RBPJ,NR2F2,ARRB2,SNX14 |
| 3.427e-03 | -5.68 | meninges-meningioma-transitional | COSMIC cancer mutations | meninges-meningioma-transitional | 15 | 7 | 17385 | 2587 |
CDKN2C,KRAS,NRAS,PTEN,HRAS,SMAD4,CDKN2A |
| 3.427e-03 | -5.68 | testis-germ_cell_tumour-mixed | COSMIC cancer mutations | testis-germ_cell_tumour-mixed | 15 | 7 | 17385 | 2587 |
KRAS,STK11,NRAS,VHL,SF3B1,HRAS,CDKN2A |
| 3.427e-03 | -5.68 | dysgerminoma | COSMIC cancer mutations | dysgerminoma | 15 | 7 | 17385 | 2587 |
KRAS,BRCA1,DNMT3A,NRAS,HRAS,SMAD4,CDKN2A |
| 3.427e-03 | -5.68 | transitional | COSMIC cancer mutations | transitional | 15 | 7 | 17385 | 2587 |
CDKN2C,KRAS,NRAS,PTEN,HRAS,SMAD4,CDKN2A |
| 3.427e-03 | -5.68 | soft_tissue-fibrous_tissue_and_uncertain_origin-gastrointestinal_stromal_tumour-epithelioid | COSMIC cancer mutations | soft_tissue-fibrous_tissue_and_uncertain_origin-gastrointestinal_stromal_tumour-epithelioid | 15 | 7 | 17385 | 2587 |
RB1,KRAS,FUS,NF1,PTEN,HRAS,CDKN2A |
| 3.427e-03 | -5.68 | ovary-germ_cell_tumour-dysgerminoma | COSMIC cancer mutations | ovary-germ_cell_tumour-dysgerminoma | 15 | 7 | 17385 | 2587 |
KRAS,BRCA1,DNMT3A,NRAS,HRAS,SMAD4,CDKN2A |
| 3.427e-03 | -5.68 | meninges-meningioma-anaplastic | COSMIC cancer mutations | meninges-meningioma-anaplastic | 15 | 7 | 17385 | 2587 |
CDKN2C,KRAS,NRAS,PTEN,HRAS,SMAD4,CDKN2A |
| 3.427e-03 | -5.68 | biliary_tract-bile_duct-carcinoma | COSMIC cancer mutations | biliary_tract-bile_duct-carcinoma | 15 | 7 | 17385 | 2587 |
KRAS,NRAS,SF3B1,HRAS,SMAD4,CDKN2A,RAC1 |
| 3.427e-03 | -5.68 | meninges-meningioma-atypical | COSMIC cancer mutations | meninges-meningioma-atypical | 15 | 7 | 17385 | 2587 |
CDKN2C,KRAS,NRAS,PTEN,HRAS,SMAD4,CDKN2A |
| 3.430e-03 | -5.68 | RPAP1 (RNA polymerase II associated protein 1) | protein interactions | 26015 | 49 | 16 | 17029 | 2761 |
SRP72,MCM10,POLR2L,POLK,LAGE3,ILF3,ERBIN,KIF11,ZFR,MAGED2,TERF2IP,POLR2J,EFTUD2,IGBP1,ARHGAP23,POT1 |
| 3.430e-03 | -5.68 | YKT6 (YKT6 v-SNARE homolog) | protein interactions | 10652 | 49 | 16 | 17029 | 2761 |
MIF,USO1,MDH2,UFC1,MEMO1,TKT,TMEM216,UBE2V1,SPR,GOSR1,LMNA,ARL6IP6,FKBP1A,DBI,PTAR1,TAGLN2 |
| 3.430e-03 | -5.68 | PYGL (glycogen phosphorylase L) | protein interactions | 5836 | 49 | 16 | 17029 | 2761 |
STAU1,H2AFZ,PSMB7,EZR,BRCA1,SND1,MCM2,PSMD9,RAD23A,PA2G4,HUWE1,MCM5,ANXA5,FKBP5,AHCY,PFKP |
| 3.430e-03 | -5.68 | Cebpb (CCAAT/enhancer binding protein beta) | protein interactions | 24253 | 49 | 16 | 17029 | 2761 |
RFC3,RHOA,POLR2L,SHPRH,PRKDC,RFXANK,SMARCA4,RXRB,TFAP4,RPA2,TERF2IP,USF1,NAP1L1,HMGB2,BEND3,NR2F2 |
| 3.430e-03 | -5.68 | Dync1li1 (dynein cytoplasmic 1 light intermediate chain 1) | protein interactions | 235661 | 49 | 16 | 17029 | 2761 |
SUGP1,SNUPN,GOLIM4,DNAJC8,SCAMP3,DYNLL1,TTC9C,DCTN2,U2SURP,DNM2,PITPNA,ROCK1,ASB6,KCNAB2,DYNC1LI2,DCTN1 |
| 3.430e-03 | -5.68 | FKBP2 (FK506 binding protein 2) | protein interactions | 2286 | 49 | 16 | 17029 | 2761 |
PPIB,DNAJC2,UBQLN4,TXN,RAB6A,NUTF2,MAPK3,EPB41,GLOD4,FKBP1A,HINT1,PTGES3,TAGLN2,LTA4H,CDKN2A,GPX4 |
| 3.431e-03 | -5.67 | positive regulation of translation | biological process | GO:0045727 | 110 | 28 | 17256 | 2622 |
EIF5A,COA3,RHOA,POLR2G,NCK1,CDC123,FAM129A,EIF3D,HABP4,DHX9,CIRBP,POLR2D,YTHDF3,EIF2AK4,SOX4,FXR1,METTL3,RPS9,SERP1,PAIP1,MAPK3,FASTKD3,EIF4A3,MRPS27,RBM3,MAPK1,PABPC1,NSUN4 |
| 3.431e-03 | -5.67 | HIV elongation arrest and recovery | REACTOME pathways | R-HSA-167287 | 40 | 14 | 10287 | 1696 |
CCNK,CTDP1,POLR2I,POLR2J,POLR2G,POLR2L,POLR2K,ELOA,POLR2D,TCEA1,POLR2A,GTF2F1,SSRP1,SUPT16H |
| 3.431e-03 | -5.67 | Pausing and recovery of HIV elongation | REACTOME pathways | R-HSA-167290 | 40 | 14 | 10287 | 1696 |
CCNK,CTDP1,POLR2I,POLR2J,POLR2G,POLR2L,POLR2K,ELOA,POLR2D,TCEA1,POLR2A,GTF2F1,SSRP1,SUPT16H |
| 3.434e-03 | -5.67 | positive regulation of mitotic nuclear division | biological process | GO:0045840 | 52 | 16 | 17256 | 2622 |
TGFB1,PHB2,CDT1,CUL3,NUSAP1,LRP5,BECN1,RB1,NSMCE2,CDCA5,H2AFY,NUP62,UBE2C,SLF1,SLF2,ESPL1 |
| 3.434e-03 | -5.67 | tRNA aminoacylation | biological process | GO:0043039 | 52 | 16 | 17256 | 2622 |
KARS,LARS,HARS,MRPL39,POLG2,TARS,EPRS,FARSA,GATC,IARS,QARS,IARS2,PPA2,QRSL1,PPA1,CARS2 |
| 3.436e-03 | -5.67 | TCF3 (transcription factor 3) | protein interactions | 6929 | 152 | 38 | 17029 | 2761 |
TCF12,IMMT,MRPL39,TCF3,INO80E,UBE2I,PSMD9,PCBP1,MYL6B,RPL23A,RB1,USF1,NDUFB4,RPN2,ALDH18A1,FBL,TIMM50,EIF5A,CCT2,KAT2A,MAPKAPK3,LDB1,RCOR1,DDX20,MEN1,MAPK3,DDX17,CHCHD3,RPL37,PON2,DNAJC10,KIF18A,HNRNPR,STK38,SAFB,YY1,RNF14,MAPK1 |
| 3.436e-03 | -5.67 | Regulation of RAS by GAPs | REACTOME pathways | R-HSA-5658442 | 70 | 21 | 10287 | 1696 |
NRAS,PSMA8,RBX1,NF1,PSMB7,CUL3,PSMA1,KRAS,PSMD9,PSMB9,PSMB3,PSMC4,PSMD2,PSMA6,PSMD1,RPS27A,PSMD8,PSMD3,KBTBD7,PSMC1,HRAS |
| 3.442e-03 | -5.67 | GO_POSITIVE_REGULATION_OF_TRANSCRIPTION_FROM_RNA_POLYMERASE_II_PROMOTER | MSigDB lists | GO_POSITIVE_REGULATION_OF_TRANSCRIPTION_FROM_RNA_POLYMERASE_II_PROMOTER | 970 | 177 | 17377 | 2626 |
ZBED3,CCNC,H2AFZ,AGRN,HEXB,SIRT2,CCNL2,MAPK14,PARK7,CREM,TET3,USF1,GLIS2,ZNF639,PIK3R2,ETV6,ECD,MYBL1,SENP1,ARID4A,SP3,AATF,NCK1,GABPA,AKT2,LRP5,BRCA1,EAF2,SOX4,CBFB,ARF4,PAF1,HHEX,SMAD2,RPS27A,E2F4,OGT,ZNF268,RNASEL,TFDP2,SMAD1,PSMC1,HDAC2,ZNF564,DDX58,HSPH1,PPP1R12A,NACA,CHCHD2,CTCF,MEF2A,PPP3CB,THRAP3,EZH1,RLF,ASXL2,CRLF3,CDC73,LMNA,TFAP4,RB1,SUB1,NFATC3,MED10,SSBP3,ZNF746,BUD31,CTR9,YBX1,MAML1,ERLIN1,MTA2,LDB1,MYBL2,RTF1,NFATC2IP,ADRB2,EIF2A,CBFA2T2,ELK1,KDM3A,IRF5,PSMC4,CAND1,RXRB,ETS2,RBMX,SETD3,CEBPG,PPP3R1,PIAS2,NLRC5,RUVBL2,CDKN2A,TCF12,ASH1L,FOXM1,RAF1,RPS6KA1,PLAGL2,SMARCA4,APP,NRF1,PIN1,GMEB1,LPIN2,TARDBP,MAVS,ATF2,RBM15,RPRD1B,MOSPD1,BRD4,WBP2,NFATC2,MEF2D,TRIM28,DDX17,TAF2,SCAP,RBL1,STAT6,HIPK2,MAFK,SAFB,ARNTL,STAT1,ATF6,NCOA1,AKNA,SMAD4,BCL2L12,POU3F2,SLC30A9,EYA1,TCF3,KLF13,ABHD14B,HMGN3,WDR5,ETS1,FOXO3,WWP2,GTF2F1,CCNK,IRF4,ARHGEF2,CREB1,CITED2,STAT3,NCOA2,TGFB1,PPP3CA,DCAF6,KAT2A,PRKDC,RFXANK,MEN1,KLF6,FADD,MAPK3,TFEB,ATAD2,TFE3,PITX1,TFDP1,E2F1,PKD2,HMGB2,DDX5,RBPJ,ZMIZ1,USF2,IGBP1,CD81,HRAS,IFI16 |
| 3.442e-03 | -5.67 | vacuolar lumen | cellular component | GO:0005775 | 171 | 39 | 18223 | 2701 |
ADA2,AGRN,MANBA,HEXB,SDC2,ASAH1,MAN2B1,NHLRC3,GYG1,GNS,PA2G4,CTSS,PSMD1,GM2A,CCT2,FTL,ACP2,CREG1,PPT1,GALC,ARHGAP45,GBA,HEBP2,TOLLIP,CCT8,NEU1,CTSL,SCARB2,SGSH,DSN1,NAGLU,ACLY,IMPDH1,CTSA,PSAP,HEXA,MAPK1,CHID1,TUBB |
| 3.444e-03 | -5.67 | DNA strand elongation | REACTOME pathways | R-HSA-69190 | 32 | 12 | 10287 | 1696 |
GINS1,POLA2,RPA2,PCNA,RFC3,PRIM2,MCM5,MCM2,RFC2,GINS4,RPA1,PRIM1 |
| 3.467e-03 | -5.66 | GO_NEGATIVE_REGULATION_OF_PROTEIN_SERINE_THREONINE_KINASE_ACTIVITY | MSigDB lists | GO_NEGATIVE_REGULATION_OF_PROTEIN_SERINE_THREONINE_KINASE_ACTIVITY | 126 | 31 | 17377 | 2626 |
PLK1,TNFAIP3,NF1,PRKAR1B,CIB1,CUL3,GBA,LRP5,DNAJA1,MEN1,RGS2,DUSP22,LYN,CDKN2C,TFAP4,PPP2CA,HHEX,MBIP,PTEN,DUSP3,GPS2,STK38,FBXO7,H2AFY,CDKN1B,NUP62,NR2F2,UBE2C,HIPK3,CDKN2A,PDCD4 |
| 3.470e-03 | -5.66 | CLK1 (CDC like kinase 1) | protein interactions | 1195 | 167 | 41 | 17029 | 2761 |
TP53RK,NF1,SF3B1,SRSF6,DNAJC24,KLC1,KIF23,THRAP3,RLF,MFSD10,LMNA,GOLM1,GSDMB,CWC27,PPIG,SSBP3,KIF14,TRA2B,NUP153,RBM15,CDK12,SRPK2,YTHDC1,PRKDC,CUL3,CRNKL1,ARHGEF12,BCLAF1,SRSF5,SYMPK,ISG15,SRSF1,GEMIN5,HSPBP1,RBMX,LUC7L3,SAFB,PRDX5,PRPF4,SRSF3,PRPF4B |
| 3.470e-03 | -5.66 | TNFRSF1A (TNF receptor superfamily member 1A) | protein interactions | 7132 | 167 | 41 | 17029 | 2761 |
MAGEH1,CYLD,C1orf112,STRN4,SIKE1,KIF2C,UBE2I,BIRC2,XPR1,MOAP1,PSMD2,BABAM2,THADA,KIF14,PTPN11,DAPK1,TNPO3,TPCN1,FGFR1OP2,MOB4,ADAM17,RHOA,FOXK1,BIRC3,TNFAIP3,STRIP1,UTP15,PIP4K2C,EZR,CDC6,FADD,FAS,OPTN,UTP20,SYNCRIP,JAK1,PRDX3,STAT1,LMBR1,ATF6,MAPK1 |
| 3.473e-03 | -5.66 | spinal_cord | COSMIC cancer mutations | spinal_cord | 149 | 35 | 17385 | 2587 |
RAB14,EWSR1,NF1,ITGB5,DST,FGFR3,RB1,CTSS,BRPF3,PTEN,MCM5,ETV6,ATP13A3,MSH2,PTPN11,RP2,MSH6,CARM1,ABCC5,NRAS,VHL,MKI67,PLEKHM3,KRAS,ANAPC2,BRCA1,MEN1,KMT2C,GNAS,STK11,H3F3A,CCNB2,HRAS,SMAD4,CDKN2A |
| 3.475e-03 | -5.66 | Negative regulators of RIG-I/MDA5 signaling | REACTOME pathways | R-HSA-936440 | 36 | 13 | 10287 | 1696 |
DDX58,UBE2D3,OTUD5,CYLD,TNFAIP3,RPS27A,PIN1,NLRC5,IRF3,MAVS,RNF135,PCBP2,ISG15 |
| 3.477e-03 | -5.66 | GSE28237_EARLY_VS_LATE_GC_BCELL_DN | MSigDB lists | GSE28237_EARLY_VS_LATE_GC_BCELL_DN | 184 | 42 | 17377 | 2626 |
WASF2,OTUD5,PRKAB1,LZTR1,PKP4,THOC1,AGTRAP,RHOC,CAST,TCF3,SNX15,CCM2,MED13L,MYH9,METTL3,REPS1,RPL23A,ATP6V0B,VASP,RRBP1,NSFL1C,AQR,TECR,AHCYL1,PLCL2,MGAT5,KCNAB2,KDM3B,ATP13A1,TSTA3,PBXIP1,ADSL,PLEC,DDX23,TPD52L2,SERF2,DUS3L,SAFB,STAT6,LIMK1,PPA2,PPP1R11 |
| 3.477e-03 | -5.66 | SHEPARD_CRUSH_AND_BURN_MUTANT_UP | MSigDB lists | SHEPARD_CRUSH_AND_BURN_MUTANT_UP | 184 | 42 | 17377 | 2626 |
SLC12A7,TOMM20,ADAM10,PHB2,MRPS26,OLA1,PTP4A3,FOXO3,HAUS2,SSR1,MDM2,RPF2,FBL,MCMBP,FTSJ3,HTRA2,PPAN,PLK3,CIC,BTG2,LYRM1,NOL8,NSUN2,ABCF2,HSDL1,MRPL12,PFKFB3,UTP3,ODC1,GAR1,TSR2,BOLA3,HSPA4,NIP7,ZNF330,TIMM17A,QARS,GADD45B,FTSJ1,IMPDH1,RRS1,TOB1 |
| 3.477e-03 | -5.66 | GSE16385_IFNG_TNF_VS_IL4_STIM_MACROPHAGE_ROSIGLITAZONE_TREATED_DN | MSigDB lists | GSE16385_IFNG_TNF_VS_IL4_STIM_MACROPHAGE_ROSIGLITAZONE_TREATED_DN | 184 | 42 | 17377 | 2626 |
CHMP2A,SCAMP3,KLHL21,RHOC,BABAM1,HEXB,MYH9,AGPAT3,TMED3,RAB6A,MIEN1,LYN,ABHD14A,NDUFS7,PRNP,MAT2B,GNS,CAPN2,C18orf32,NDUFB4,POP7,ZNF335,PDCD2,LPCAT1,PPP6R1,TMED2,TMEM160,TGFB1,PTPN18,TSPAN31,PCGF6,RABIF,RAB5B,GAR1,HMGN2,BOLA3,CTBS,SLC25A19,TMEM14A,RNF139,TERF1,MYL12B |
| 3.477e-03 | -5.66 | GSE5503_LIVER_DC_VS_SPLEEN_DC_ACTIVATED_ALLOGENIC_TCELL_DN | MSigDB lists | GSE5503_LIVER_DC_VS_SPLEEN_DC_ACTIVATED_ALLOGENIC_TCELL_DN | 184 | 42 | 17377 | 2626 |
WSB2,SLC30A9,OTUD5,C1orf74,TRIM41,GGNBP2,UBR2,RACGAP1,UBE4A,ATP6V1B2,GLRX3,VPS25,WWP2,LIN9,ATP6V0B,MED10,DNAAF2,PPP1R12C,DDX31,RNF19A,ALDH18A1,ZNF800,FYTTD1,EIF3L,ULK3,PBXIP1,MRS2,UTP15,SCFD2,RABIF,NUP155,DNAJA1,BICD2,ANLN,FXR1,NMT2,GOLGA4,DBI,TBPL1,ACBD4,RUFY3,CLN3 |
| 3.477e-03 | -5.66 | GSE41176_UNSTIM_VS_ANTI_IGM_STIM_BCELL_6H_DN | MSigDB lists | GSE41176_UNSTIM_VS_ANTI_IGM_STIM_BCELL_6H_DN | 184 | 42 | 17377 | 2626 |
SLC30A9,CCNC,MAGEH1,ATXN3,ADAM10,PHRF1,DLGAP4,SMC6,AGFG1,THRAP3,SLC25A44,GGPS1,STAM,CPNE3,RNF103,DTL,C1GALT1,KIF13B,AXIN2,CDKN2AIP,HMGN5,RB1CC1,RDH10,E2F3,EMP3,CDC6,PPWD1,PTTG1IP,PATL1,HHEX,MID1IP1,PDLIM1,GRIPAP1,HNRNPH3,SIAH2,PIAS2,DUSP11,CENPT,MBD6,FBXL3,B4GALT3,ZC3HAV1 |
| 3.477e-03 | -5.66 | GSE34515_CD16_NEG_MONOCYTE_VS_DC_UP | MSigDB lists | GSE34515_CD16_NEG_MONOCYTE_VS_DC_UP | 184 | 42 | 17377 | 2626 |
RAB14,CDS2,H2AFZ,PLXNC1,XAB2,RHOC,NACA,KIAA0232,PLAGL2,MED13L,ASAH1,DAZAP2,CRLF3,APH1B,CMTM6,MAN1A1,MDM2,INPP5A,MBD2,DAPK1,RP2,PTGES3,LDLRAD3,RNF135,SP3,ELL2,MAPKAPK3,NEK7,MTMR6,EAF2,KDM1B,RHBDF2,HAUS8,SDHB,SCARB2,FAM110A,RAB24,OSBPL8,ITGB1,MBOAT1,LTA4H,ZBTB11 |
| 3.477e-03 | -5.66 | GSE17721_LPS_VS_PAM3CSK4_16H_BMDC_DN | MSigDB lists | GSE17721_LPS_VS_PAM3CSK4_16H_BMDC_DN | 184 | 42 | 17377 | 2626 |
MMACHC,NCOR2,TMED7,NDUFB6,RRP15,HJURP,SEC61G,TMEM109,STARD7,MEF2A,STMN1,SRRT,PABPC4,SRXN1,ATP6V0B,RRN3,SNX18,BANF1,ARHGEF1,ADCY9,MECR,YBX1,GM2A,SMC4,CYFIP1,SEC61B,NSDHL,RPS10,WBP2,HAGH,STK17B,RPS9,MAPK3,SYNCRIP,SERF2,GRIPAP1,ACOX1,WDR4,ACADM,TSPAN5,SMAD4,SLC25A39 |
| 3.477e-03 | -5.66 | GSE17721_POLYIC_VS_GARDIQUIMOD_2H_BMDC_DN | MSigDB lists | GSE17721_POLYIC_VS_GARDIQUIMOD_2H_BMDC_DN | 184 | 42 | 17377 | 2626 |
UBE2D3,HSPH1,RRP15,ANXA6,SLC41A1,LAMTOR3,DNAJC24,DHX8,TM9SF3,MEF2A,PRPF39,RNF103,SRXN1,MDM2,VASP,TNFAIP8,DDA1,PTPN11,INTS12,RNF19A,MRPL11,CPNE1,CSRP1,BTG2,OXR1,ATP2C1,TAZ,STK17B,ZDHHC3,GINS4,YIF1A,SURF4,ETS2,STT3A,TBL3,PITX1,MAPK6,U2SURP,HRAS,LONP2,MRPL3,ZC3HC1 |
| 3.481e-03 | -5.66 | NACA2 (nascent polypeptide associated complex subunit alpha 2) | protein interactions | 342538 | 21 | 9 | 17029 | 2761 |
PCNA,RPL32,NACA,BTF3L4,TUFM,BCAP29,PTGES3,BTF3,CDK2 |
| 3.481e-03 | -5.66 | AP4S1 (adaptor related protein complex 4 subunit sigma 1) | protein interactions | 11154 | 21 | 9 | 17029 | 2761 |
CEP104,GOLIM4,GALNT2,SUV39H2,TIMM29,MECP2,AP4E1,CDC73,APP |
| 3.481e-03 | -5.66 | GNG12 (G protein subunit gamma 12) | protein interactions | 55970 | 21 | 9 | 17029 | 2761 |
RAP1A,FLOT1,MYH9,MEF2A,ADRB2,PKM,SLC12A2,GNB2,CAPN1 |
| 3.481e-03 | -5.66 | RBMY1A1 (RNA binding motif protein, Y-linked, family 1, member A1) | protein interactions | 5940 | 21 | 9 | 17029 | 2761 |
ZNF317,CLK3,RBMX,CIRBP,AEN,TRA2B,RBM3,SRSF3,TERF1 |
| 3.481e-03 | -5.66 | Kif1bp (KIF1 binding protein) | protein interactions | 72320 | 21 | 9 | 17029 | 2761 |
KIF18A,PPP1R12A,KIF14,MIER1,MYO18A,AP2B1,ACTB,SEC16A,SPTAN1 |
| 3.481e-03 | -5.66 | MYOF (myoferlin) | protein interactions | 26509 | 21 | 9 | 17029 | 2761 |
RPA2,SCARB2,PTEN,RAB7A,XRCC3,CDK2,MATR3,ISG15,RPA1 |
| 3.481e-03 | -5.66 | RASGRF1 (Ras protein specific guanine nucleotide releasing factor 1) | protein interactions | 5923 | 21 | 9 | 17029 | 2761 |
PPP1R9B,RHOA,GRK2,EHD4,SNRNP70,PRKACA,HRAS,RAC1,SRPK2 |
| 3.481e-03 | -5.66 | PDE3A (phosphodiesterase 3A) | protein interactions | 5139 | 21 | 9 | 17029 | 2761 |
CSDE1,UBE4B,WDR62,ATP6V1B2,PRKACA,KIF11,DPYSL2,FBXO7,MSH2 |
| 3.481e-03 | -5.66 | GALE (UDP-galactose-4-epimerase) | protein interactions | 2582 | 21 | 9 | 17029 | 2761 |
MAT2B,GALK2,ACADM,ARF1,TSTA3,WDR1,AHSA1,APP,MAPK3 |
| 3.481e-03 | -5.66 | Itsn2 (intersectin 2) | protein interactions | 20403 | 21 | 9 | 17029 | 2761 |
BCCIP,EIF3L,MKNK1,EIF4A3,EIF3G,ZMAT3,DBI,EIF3A,EIF3H |
| 3.481e-03 | -5.66 | RNMT (RNA guanine-7 methyltransferase) | protein interactions | 8731 | 21 | 9 | 17029 | 2761 |
KPNA1,CUL3,KIF23,CUL1,KPNA2,NFATC2IP,BRCA1,MCM2,CAND1 |
| 3.481e-03 | -5.66 | ANGPTL4 (angiopoietin like 4) | protein interactions | 51129 | 21 | 9 | 17029 | 2761 |
TGFB1,CDKN2C,BRMS1,SMARCA4,ACTB,PM20D2,ARMC8,CDKN2A,NMT2 |
| 3.483e-03 | -5.66 | CGB2 (chorionic gonadotropin subunit beta 2) | protein interactions | 114336 | 14 | 7 | 17029 | 2761 |
CYFIP1,NCKAP1,KDM2A,CYFIP2,PITRM1,MTA2,ABI1 |
| 3.483e-03 | -5.66 | ZNF511 (zinc finger protein 511) | protein interactions | 118472 | 14 | 7 | 17029 | 2761 |
WASF2,CYFIP1,NCKAP1,CYFIP2,LSM6,KLHL15,ABI1 |
| 3.483e-03 | -5.66 | INTS8 (integrator complex subunit 8) | protein interactions | 55656 | 14 | 7 | 17029 | 2761 |
INTS2,CTDP1,INTS7,INTS1,C7orf26,GLMP,CDC5L |
| 3.483e-03 | -5.66 | IER3 (immediate early response 3) | protein interactions | 8870 | 14 | 7 | 17029 | 2761 |
MCL1,MDM2,MAPK1,APP,MAPK3,PML,PRNP |
| 3.483e-03 | -5.66 | PIP (prolactin induced protein) | protein interactions | 5304 | 14 | 7 | 17029 | 2761 |
DDX31,CYLD,MCM2,MCM5,TCF3,PHF6,WWP2 |
| 3.483e-03 | -5.66 | UPP1 (uridine phosphorylase 1) | protein interactions | 7378 | 14 | 7 | 17029 | 2761 |
CTDP1,MCM2,WDR45B,GPD1L,CUTA,WBP2,UCK2 |
| 3.483e-03 | -5.66 | UL29 (contains a zinc-finger; involved in DNA replication; possibly involved in gene regulation) | protein interactions | 2703458 | 14 | 7 | 17029 | 2761 |
SMARCA4,SMARCE1,PRKDC,HDAC2,IFI16,RPA1,XRCC5 |
| 3.483e-03 | -5.66 | Pcdh1 (protocadherin 1) | protein interactions | 75599 | 14 | 7 | 17029 | 2761 |
SMARCA4,TAF12,RNF14,DDX39A,C2CD5,SUGP2,SRI |
| 3.483e-03 | -5.66 | HIST1H2AL (histone cluster 1 H2A family member l) | protein interactions | 8332 | 14 | 7 | 17029 | 2761 |
TERF2IP,CUL1,BRD7,PCGF1,MCM2,CAND1,SAP30 |
| 3.483e-03 | -5.66 | Gtf2b (general transcription factor IIB) | protein interactions | 229906 | 14 | 7 | 17029 | 2761 |
CTDP1,POLR2I,EIF4ENIF1,POLR2J,CDK12,POLR2A,GTF2F1 |
| 3.483e-03 | -5.66 | Sept11 (septin 11) | protein interactions | 52398 | 14 | 7 | 17029 | 2761 |
SEPT8,BEND3,EIF2AK4,SEPT7,SEPT9,BECN1,ZMAT3 |
| 3.483e-03 | -5.66 | RPA4 (replication protein A4) | protein interactions | 29935 | 14 | 7 | 17029 | 2761 |
RPA2,APP,XPA,RPA1,SSRP1,SUPT16H,MSH2 |
| 3.483e-03 | -5.66 | BIK (BCL2 interacting killer) | protein interactions | 638 | 14 | 7 | 17029 | 2761 |
CRKL,MCL1,BCL2,BCL2L1,NR2F2,APP,TANK |
| 3.483e-03 | -5.66 | Tmem109 (transmembrane protein 109) | protein interactions | 68539 | 14 | 7 | 17029 | 2761 |
RPN2,USP11,VDAC1,PHB2,ASXL2,BCAP31,VDAC2 |
| 3.490e-03 | -5.66 | GSE22342_CD11C_HIGH_VS_LOW_DECIDUAL_MACROPHAGES_UP | MSigDB lists | GSE22342_CD11C_HIGH_VS_LOW_DECIDUAL_MACROPHAGES_UP | 168 | 39 | 17377 | 2626 |
MYH9,RACGAP1,NIPA2,MAPK14,FAM8A1,PRNP,SMC3,ZNF746,DCP1A,POLR1B,PRADC1,NAA35,GM2A,MYO5A,CYTH1,TSPAN31,LRRC8A,GORAB,MAP4K3,UTP3,AMDHD2,ZNF407,GOSR1,KRIT1,PRIM1,PLD3,RAB18,AHNAK,ATAD2,ORMDL2,NFIL3,BBX,USP32,VCPIP1,UQCRH,PPP6R3,SNRNP70,PSMC1,NUDT3 |
| 3.490e-03 | -5.66 | p53 binding | molecular function | GO:0002039 | 70 | 20 | 17224 | 2647 |
PLK3,USP7,BCL2L12,CDKN2AIP,BRD4,TP53RK,EHMT1,USP10,RFFL,SMARCA4,PTTG1IP,BLM,RFWD3,CDK5,MDM2,KMT5A,BRD7,STK11,TP53BP2,ZMAT3 |
| 3.492e-03 | -5.66 | cell aging | biological process | GO:0007569 | 66 | 19 | 17256 | 2622 |
MIF,ULK3,ERCC1,RWDD1,SMC6,MAPK14,NSMCE2,ARNTL,H2AFX,PML,NUP62,BCL2,CHEK2,ZMIZ1,HRAS,CDKN2A,PDCD4,TERF2,MORC3 |
| 3.498e-03 | -5.66 | RIZKI_TUMOR_INVASIVENESS_3D_DN | MSigDB lists | RIZKI_TUMOR_INVASIVENESS_3D_DN | 255 | 55 | 17377 | 2626 |
POLA2,PLXNC1,PRKCSH,B4GALT5,XIAP,TKT,LAGE3,MYH9,ABCB10,GFM2,RBM4,SRRT,BCAP31,KIFC1,HERC3,FKBP1A,PDCD10,CDC42,DUS4L,SEC24C,BDH1,PDCD2,OSTF1,ORC3,PHKG2,ARID4A,TXNL1,AMPD2,PLK1,TK1,POLR2L,CELSR2,RRM2,USP22,ICMT,FXR1,VDAC1,MCM2,ZFAND5,NEU1,EPB41,DDX17,RPL37,SEC23IP,NEK1,TONSL,ZNF330,QARS,SSNA1,ROCK1,MAP3K5,CD81,LRP8,MYL12B,PDCD4 |
| 3.505e-03 | -5.65 | nuclear-transcribed mRNA catabolic process, no-go decay | biological process | GO:0070966 | 3 | 3 | 17256 | 2622 |
CSDE1,CNOT6,PELO |
| 3.505e-03 | -5.65 | regulation of exonuclease activity | biological process | GO:1905777 | 3 | 3 | 17256 | 2622 |
TCEA1,TERF1,TERF2 |
| 3.505e-03 | -5.65 | nuclear protein quality control by the ubiquitin-proteasome system | biological process | GO:0071630 | 3 | 3 | 17256 | 2622 |
ANKZF1,KLHL15,CUL3 |
| 3.505e-03 | -5.65 | PMA-inducible membrane protein ectodomain proteolysis | biological process | GO:0051088 | 3 | 3 | 17256 | 2622 |
ADAM9,ADAM17,ADAM10 |
| 3.509e-03 | -5.65 | KAT5 (lysine acetyltransferase 5) | protein interactions | 10524 | 228 | 53 | 17029 | 2761 |
USP7,NDUFV2,MAX,MAPRE1,H2AFZ,GADD45G,HABP4,RRM1,PLAGL2,GMCL1,CCNB1,UBE2I,APP,MEAF6,LMNA,PHC2,RB1,APLP2,MDM2,PCNA,CDC42,HDAC7,ETV6,CREB1,ATF2,MCPH1,STAT3,DNMT1,TELO2,VHL,PRKDC,LDHA,CUL3,ATXN1,RRM2,BRCA1,ODC1,FAS,UBTF,HINT1,GOLGA2,HNRNPH3,PML,SIAH2,UHRF2,H2AFX,E2F1,ACTB,RBPJ,RUVBL2,CDKN2A,GEMIN7,SNAPIN |
| 3.529e-03 | -5.65 | GO_CYTOSOLIC_LARGE_RIBOSOMAL_SUBUNIT | MSigDB lists | GO_CYTOSOLIC_LARGE_RIBOSOMAL_SUBUNIT | 57 | 17 | 17377 | 2626 |
RPL29,RPL35,RPLP2,RPL8,RPL6,RPL38,RPL15,RPL27A,RPL11,RPL23A,RPL36,RPL37,RPL32,RPL17,RPLP1,RPL19,RPL22L1 |
| 3.533e-03 | -5.65 | ACTGTAG,MIR-139 | MSigDB lists | ACTGTAG,MIR-139 | 121 | 30 | 17377 | 2626 |
TCF12,ZBTB10,DNAJC5,IVNS1ABP,TAOK1,HNRNPF,ATXN1,SMARCA4,RTF1,PPP3CB,EIF4G2,ETS1,DHX15,MAT2A,PHF6,PPP2CA,APLP2,KPNA4,CDC42,SRSF4,PROSER1,SEPT11,FBXL7,PIEZO1,FAM76B,RUFY3,GPD1L,TSPAN5,SRSF10,PRPF4B |
| 3.539e-03 | -5.64 | CHICAS_RB1_TARGETS_LOW_SERUM | MSigDB lists | CHICAS_RB1_TARGETS_LOW_SERUM | 76 | 21 | 17377 | 2626 |
COX5B,CKLF,DEPDC1,POLR2L,SNRPB,FAM129A,CDT1,RPL38,NDUFB1,SOX4,DTL,NDUFB4,ZNF367,MCM5,PITX1,RNASEH2A,SNRPG,C8orf59,WDR76,NDUFA3,RAD51D |
| 3.544e-03 | -5.64 | Zinc_finger_PHD-type_CS | interpro domains | IPR019786 | 67 | 19 | 18492 | 2768 |
PHF20L1,ASH1L,KMT2E,SHPRH,PHRF1,CXXC1,ZMYND11,NSD3,DIDO1,TCF19,TRIM28,SP100,BRPF3,KDM2A,CHD3,PHF14,INTS12,BAZ1B,FBXL19 |
| 3.546e-03 | -5.64 | GO_PROTEIN_ACYLATION | MSigDB lists | GO_PROTEIN_ACYLATION | 147 | 35 | 17377 | 2626 |
NAT9,ZDHHC8,MDH2,MECP2,TAF6L,WDR5,SUPT7L,MEAF6,SAP130,IRF4,BRPF3,NAA50,TAF5L,ATF2,NCOA2,ZDHHC18,KAT2A,KAT7,LDB1,ELP4,USP22,MBD3,ZDHHC3,NMT2,MBIP,GOLGA7,DBI,OGT,ZDHHC7,NCOA1,RUVBL2,TAF12,BEND3,NAA20,NAA60 |
| 3.556e-03 | -5.64 | Deadenylation-dependent mRNA decay | REACTOME pathways | R-HSA-429914 | 57 | 18 | 10287 | 1696 |
EXOSC6,EXOSC9,CNOT11,PARN,PATL1,PAIP1,CNOT3,EDC3,CNOT9,EXOSC7,LSM6,EIF4A3,NT5C3B,EXOSC1,DCP1A,CNOT6,CNOT6L,PABPC1 |
| 3.559e-03 | -5.64 | GSE7548_NAIVE_VS_DAY28_PCC_IMMUNIZATION_CD4_TCELL_UP | MSigDB lists | GSE7548_NAIVE_VS_DAY28_PCC_IMMUNIZATION_CD4_TCELL_UP | 195 | 44 | 17377 | 2626 |
RMND5A,SNX27,GLT8D1,GADD45G,RRM1,MXD4,MAPK14,PAIP1,EPM2A,TERF2IP,NFATC3,PTEN,PPIG,JOSD1,CLDND1,SOCS5,EID1,KAT7,PRKDC,ILF3,HTATIP2,WDR82,PCGF1,MCFD2,CHAF1A,RDH11,PAF1,YIF1A,SUGP1,MTMR3,PDCD6,ATP6V1D,KEAP1,ATP1A1,FBXO28,DHX16,MPV17,OGT,ITGB1,MRFAP1L1,DUSP11,RBPJ,ACADM,ATP6V0E1 |
| 3.559e-03 | -5.64 | GSE15930_NAIVE_VS_72H_IN_VITRO_STIM_IL12_CD8_TCELL_DN | MSigDB lists | GSE15930_NAIVE_VS_72H_IN_VITRO_STIM_IL12_CD8_TCELL_DN | 195 | 44 | 17377 | 2626 |
GALK1,GADD45G,SLC2A1,OLA1,TMEM97,JMJD6,POMP,FKBP2,HCFC1R1,PRKACA,SNRNP25,RB1,DECR1,CLIC4,IARS,NVL,SIVA1,PCYT2,HDHD2,S100A6,TACC3,FDFT1,SAP30,PRIM2,TSPAN31,MKI67,NUSAP1,ANLN,RFC2,TPD52L2,CDKN2AIPNL,AHNAK,MTHFD2,BIRC5,CCDC6,DCK,CRCP,ATF6,RBPJ,TMEM159,RNF14,PGAM1,HRAS,DDX52 |
| 3.559e-03 | -5.64 | GSE14769_20MIN_VS_360MIN_LPS_BMDM_DN | MSigDB lists | GSE14769_20MIN_VS_360MIN_LPS_BMDM_DN | 195 | 44 | 17377 | 2626 |
RHOG,KARS,CYLD,TXN,TMEM184B,GMFG,AGTRAP,SF3B1,FAM129A,C5orf30,CUL1,CHAC2,PSEN1,GTF2F1,SLC31A1,MED10,CWC27,AFF1,TCEA1,SGCB,GCC1,SLC25A1,RLIM,VOPP1,SRP72,PHF20L1,ORAI2,OAF,USP42,CAPZA2,SYVN1,PPFIA3,FOXRED1,DOT1L,TRAM2,KPNA4,RBL1,SCAP,CLK3,TMEM219,B4GALT3,BRWD3,MRPL3,ADAM23 |
| 3.560e-03 | -5.64 | THILLAINADESAN_ZNF217_TARGETS_UP | MSigDB lists | THILLAINADESAN_ZNF217_TARGETS_UP | 39 | 13 | 17377 | 2626 |
SRP72,MND1,GLT8D1,PDXP,SKA3,RAD51AP1,TCF3,POP7,CDCA8,PFKFB3,BRCA1,CNPY3,HAUS2 |
| 3.560e-03 | -5.64 | DELPUECH_FOXO3_TARGETS_DN | MSigDB lists | DELPUECH_FOXO3_TARGETS_DN | 39 | 13 | 17377 | 2626 |
LARS,MTHFD2,SLC1A4,IARS,FOXM1,CENPF,CEBPG,PRC1,MKI67,NUSAP1,KIF22,UBE2C,SMC4 |
| 3.560e-03 | -5.64 | GO_TRIVALENT_INORGANIC_CATION_TRANSPORT | MSigDB lists | GO_TRIVALENT_INORGANIC_CATION_TRANSPORT | 39 | 13 | 17377 | 2626 |
ATP6V0B,ATP6V1D,RAB11B,DNM2,ATP6V0A1,ATP6V0A2,ATP6V0C,ATP6V1B2,ATP6V1C1,ATP6V0D1,ATP6V0E1,TFRC,ATP6V1G1 |
| 3.560e-03 | -5.64 | GO_NUCLEAR_UBIQUITIN_LIGASE_COMPLEX | MSigDB lists | GO_NUCLEAR_UBIQUITIN_LIGASE_COMPLEX | 39 | 13 | 17377 | 2626 |
PHC2,CDC16,CDC27,RBX1,PCGF6,ANAPC2,ANAPC7,BRCA1,CDC23,UBE2C,CBX4,MAD2L2,ANAPC4 |
| 3.560e-03 | -5.64 | GO_FERRIC_IRON_TRANSPORT | MSigDB lists | GO_FERRIC_IRON_TRANSPORT | 39 | 13 | 17377 | 2626 |
ATP6V0B,ATP6V1D,RAB11B,DNM2,ATP6V0A1,ATP6V0A2,ATP6V0C,ATP6V1B2,ATP6V1C1,ATP6V0D1,ATP6V0E1,TFRC,ATP6V1G1 |
| 3.560e-03 | -5.64 | GO_MICROTUBULE_POLYMERIZATION_OR_DEPOLYMERIZATION | MSigDB lists | GO_MICROTUBULE_POLYMERIZATION_OR_DEPOLYMERIZATION | 39 | 13 | 17377 | 2626 |
ZNF207,KIF18A,GOLGA2,KIF18B,CENPJ,KIF14,TUBGCP5,KIF2C,NDE1,STMN1,TUBGCP2,CSNK1D,FBXO5 |
| 3.560e-03 | -5.64 | GO_PEPTIDYL_ASPARAGINE_MODIFICATION | MSigDB lists | GO_PEPTIDYL_ASPARAGINE_MODIFICATION | 39 | 13 | 17377 | 2626 |
RPN1,DDOST,MAGT1,DPM1,STT3A,DAD1,FUT8,RPN2,ST3GAL2,SYVN1,OSTC,LMAN1,MCFD2 |
| 3.568e-03 | -5.64 | DVL3 (dishevelled segment polarity protein 3) | protein interactions | 1857 | 99 | 27 | 17029 | 2761 |
NOL12,YTHDC1,CYLD,FOXK1,XAB2,KAT7,PPIE,RPS10,CRNKL1,CSNK2A1,PRPF3,PLEC,DIDO1,UTP3,MARK2,PPP2CA,CCNK,HUWE1,CENPJ,AXIN1,ODF2,PITX1,AQR,DVL1,DVL2,CSNK1D,CDC5L |
| 3.568e-03 | -5.64 | PICALM (phosphatidylinositol binding clathrin assembly protein) | protein interactions | 8301 | 99 | 27 | 17029 | 2761 |
UNK,EWSR1,ILF3,LAMTOR3,FLOT1,MYH9,CAPZA2,ANLN,MCM2,SEC16A,NPLOC4,PAPOLA,PTPRF,KLHL20,SEC24C,MYO18A,ITGB1,SH3GLB2,DNM2,GTSE1,AP2B1,FUS,CLTB,HNRNPDL,SMURF1,MICAL3,CDC5L |
| 3.568e-03 | -5.64 | Flnb (filamin, beta) | protein interactions | 286940 | 99 | 27 | 17029 | 2761 |
RAB14,PPP1R18,RHOA,LUZP1,RAB7A,RAC1,FLOT1,KRAS,PLEC,CAPZA2,RAB1A,LYN,RHOB,DAPK3,CD59,INF2,RAP1A,AHNAK,RALB,ARPC5,SNAP23,CAPZA1,AP2B1,CLTB,NUMB,MYO5A,SPTAN1 |
| 3.568e-03 | -5.64 | PRKCI (protein kinase C iota) | protein interactions | 5584 | 99 | 27 | 17029 | 2761 |
PDPK1,TRAPPC13,ARHGAP17,VHL,RAC1,KIF23,PAWR,MAP1LC3B,MARK2,APP,USP21,MASTL,MAGED2,EIF4ENIF1,CDC42,MTMR4,RAB4A,KBTBD7,USP20,YWHAZ,SMURF1,NIPSNAP2,YWHAH,HRAS,PARD3,NIPSNAP1,CDC37 |
| 3.568e-03 | -5.64 | RBFOX2 (RNA binding fox-1 homolog 2) | protein interactions | 23543 | 99 | 27 | 17029 | 2761 |
JMJD4,UNK,HNRNPAB,RBM42,APH1A,PRRC2A,MAGED1,CUL3,HNRNPF,ATXN1,FAM136A,DAZAP2,TOLLIP,MATR3,RBM38,CLNS1A,CHAF1A,RPA1,RPA2,RBM23,GLIS2,TIMM29,FBXO7,RBMS1,PARL,BRD7,DDX5 |
| 3.587e-03 | -5.63 | BAX (BCL2 associated X, apoptosis regulator) | protein interactions | 581 | 85 | 24 | 17029 | 2761 |
BAK1,BCL2L12,XIAP,MCL1,CYCS,BCL2L1,SEPT7,TOMM40,PKM,VDAC1,PCBP1,EDRF1,PARK7,PRDX1,SH3GLB1,XRCC5,MOAP1,HSPA4,NSFL1C,UHRF2,BCL2,CLU,YY1,ZBTB24 |
| 3.608e-03 | -5.62 | LIG4 (DNA ligase 4) | protein interactions | 3981 | 123 | 32 | 17029 | 2761 |
AGO2,RPL11,HNRNPA2B1,ZNF428,PA2G4,PSMA6,WBP1L,TAGLN2,ATP6V0D1,RHBDD2,MICAL3,KDELR1,LDHB,CPNE1,PHF10,PPP1R18,HMGN1,LAP3,PRKDC,ASPM,OXR1,LDHA,EIF2AK1,SMC2,COA7,VKORC1,MAP2K2,NEU1,XRCC5,RUVBL2,CLU,XRCC4 |
| 3.608e-03 | -5.62 | AMFR (autocrine motility factor receptor) | protein interactions | 267 | 123 | 32 | 17029 | 2761 |
UBE2D3,TMUB1,ATXN3,UBXN1,MYH9,NPLOC4,PRNP,PSMA6,ATP2A2,MAVS,RNF5,TIMM50,SEC61B,ATG9A,ERLIN1,PSMB7,PSMA1,ADRB2,SYVN1,RHOT1,TRIM28,PSMB3,DERL1,HSPA4,PSMD3,OSBPL8,SEL1L,SARAF,GPI,FAF1,USP13,SVIP |
| 3.608e-03 | -5.62 | SMARCC1 (SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 1) | protein interactions | 6599 | 123 | 32 | 17029 | 2761 |
EWSR1,ADD1,ARID2,DCTN2,SMARCA4,TOP2B,NSD3,ARID1B,BRD7,SS18L1,MCPH1,SMARCE1,CARM1,PHF10,CUL3,NFATC2,PBRM1,ARID1A,BRCA1,AURKB,TRIM28,CAND1,SMAD2,C1orf131,BCL7C,KHSRP,BAZ1B,STK11,NCOA1,TAF6,FUBP1,SMARCD1 |
| 3.618e-03 | -5.62 | PTEN (phosphatase and tensin homolog) | protein interactions | 5728 | 296 | 66 | 17029 | 2761 |
USP7,TXN,RPLP2,NF1,MCCC1,XIAP,CSNK2A1,USP39,UBE2I,PARK7,MXD1,CRKL,FBXL6,PIK3R2,ANAPC7,MAST2,METTL26,CFL1,PLK1,BRD4,TRIM8,OSBP2,VHL,PBK,RPL38,DNAJA1,PKMYT1,SLC25A5,RPS9,ARF4,RPS27A,HAGHL,STK11,ROCK1,COPS6,RPS26,TUBB,USP13,PIGN,RPS2,ETS1,WWP2,PTEN,PELO,MVP,GNAI2,RPL22L1,SPTAN1,CARS2,LDHB,PPP3CA,RHOA,TUFM,USP10,PLEC,OTUD3,PKM,RPL27A,PRDX1,MTHFD2,CDC27,DCAF11,ATP5F1A,DDB1,CDKN2A,ANAPC4 |
| 3.620e-03 | -5.62 | GO_PHOSPHATASE_REGULATOR_ACTIVITY | MSigDB lists | GO_PHOSPHATASE_REGULATOR_ACTIVITY | 81 | 22 | 17377 | 2626 |
ANKLE2,SHOC2,PPP1R9B,PPP1R37,PPP1R12A,PPP1R2,ENSA,CSNK2A1,MTMR12,PPP1R16B,GTF2F1,CALM2,PPP1R3B,PPP2R5A,PPP1R8,PPME1,PPP4R1,PPP1R11,ANP32E,CABIN1,IGBP1,PPP2R2D |
| 3.628e-03 | -5.62 | Aurora B signaling | Pathway Interaction DB | aurora_b_pathway | 39 | 15 | 2226 | 426 |
RHOA,SEPT1,BIRC5,TACC1,NSUN2,CDCA8,CUL3,KIF23,RACGAP1,KIF2C,SMC2,AURKB,NCAPG,STMN1,SMC4 |
| 3.639e-03 | -5.62 | MAIP1 (matrix AAA peptidase interacting protein 1) | protein interactions | 79568 | 45 | 15 | 17029 | 2761 |
NDUFA5,PTPN18,TIMMDC1,MCCC1,TIMM21,CHCHD2,SLC25A19,NDUFA4,XPNPEP3,MCM2,LYN,EYA2,ACSF2,APP,STOML2 |
| 3.639e-03 | -5.62 | COMMD8 (COMM domain containing 8) | protein interactions | 54951 | 45 | 15 | 17029 | 2761 |
CCDC93,COMMD10,ATP6V1D,VPS26C,CCDC14,TFDP1,CUL3,CUL1,COG1,BOLA1,TFDP2,COMMD5,COMMD4,COMMD6,VPS29 |
| 3.639e-03 | -5.62 | Cdc23 (CDC23 cell division cycle 23) | protein interactions | 52563 | 45 | 15 | 17029 | 2761 |
TIMM13,CDC16,CDC27,KIF18B,CUL1,KIF23,RRM2,ANAPC2,ANAPC7,CDC23,ATP5PF,ANAPC4,PARD3,PDF,FBXO5 |
| 3.639e-03 | -5.62 | KYNU (kynureninase) | protein interactions | 8942 | 45 | 15 | 17029 | 2761 |
ADSS,GNS,BCCIP,SEC23IP,NUP210,RPS6KA1,PPM1G,MEMO1,LDHA,KHSRP,SPR,LYN,COIL,CFL1,FUBP1 |
| 3.639e-03 | -5.62 | SLC39A5 (solute carrier family 39 member 5) | protein interactions | 283375 | 45 | 15 | 17029 | 2761 |
PTPN2,NAT14,ACP2,ERMP1,GOLPH3L,GPR89A,MRS2,SLC25A51,CYSTM1,MIA2,SLC35B2,METTL9,CHPT1,ABHD14A,HLA-A |
| 3.639e-03 | -5.62 | ATP6V1H (ATPase H+ transporting V1 subunit H) | protein interactions | 51606 | 45 | 15 | 17029 | 2761 |
UNK,DDX28,ATP6V1D,CDC42,RAB11B,WDR44,TANK,VDAC2,ARMT1,ATP6V1B2,ZFAND5,STMN1,ATP6V0D1,PDXDC1,ABCC1 |
| 3.639e-03 | -5.62 | RIOK1 (RIO kinase 1) | protein interactions | 83732 | 45 | 15 | 17029 | 2761 |
RPS2,SNRNP200,EIF4A3,LSM6,WDYHV1,POC1A,EFTUD2,LACTB,CIRBP,SMU1,RPL15,FBL,GAR1,SMURF1,APP |
| 3.639e-03 | -5.62 | DDX42 (DEAD-box helicase 42) | protein interactions | 11325 | 45 | 15 | 17029 | 2761 |
EPRS,MDM2,SYNCRIP,SF3B1,U2SURP,FUS,RUVBL2,APP,SF3A2,DHX15,ISG15,LMNA,RPL36,PRPF19,CDC5L |
| 3.639e-03 | -5.62 | NUP54 (nucleoporin 54) | protein interactions | 53371 | 45 | 15 | 17029 | 2761 |
HOMER1,HGS,KPNA1,ADD1,RAE1,WDR59,NUP107,AP2B1,NUP62,NUP153,NUTF2,NDE1,NUP58,IFI16,SSR1 |
| 3.641e-03 | -5.62 | GO_LIPOSACCHARIDE_METABOLIC_PROCESS | MSigDB lists | GO_LIPOSACCHARIDE_METABOLIC_PROCESS | 111 | 28 | 17377 | 2626 |
PGAP2,PIGM,PIGN,PIGT,DPM1,GALC,PIGQ,HEXB,CERK,GBA,ASAH1,SUMF1,NANS,ARSK,NEU1,CREM,ITGB8,PIGG,ST3GAL2,CTSA,GLTP,SMPD4,PSAP,CLN3,ST8SIA2,HEXA,CLN6,GM2A |
| 3.643e-03 | -5.62 | Kinesin | pfam domains | PF00225 | 44 | 14 | 17054 | 2545 |
KIF5B,KIF2A,KIFC1,STARD9,KIF3B,KIF18A,KIF18B,KIF14,KIF13B,KIF15,KIF23,KIF22,KIF2C,KIF11 |
| 3.649e-03 | -5.61 | GO_MICROTUBULE_ASSOCIATED_COMPLEX | MSigDB lists | GO_MICROTUBULE_ASSOCIATED_COMPLEX | 142 | 34 | 17377 | 2626 |
KIF3B,DYNLL1,DCTN2,CDCA8,KIF23,KLC1,HAUS4,KIF2C,HAUS2,KIFC1,KIF5B,STARD9,KIF13B,KIF14,KIFAP3,KIF22,DNAL4,DCTN1,STAU1,KIF15,TOPORS,WDR81,AURKB,KIF11,HAUS8,KIF2A,FNTA,KIF18A,KIF18B,BIRC5,MAP4,NDE1,LRP8,DYNC1LI2 |
| 3.656e-03 | -5.61 | REACTOME_P53_INDEPENDENT_G1_S_DNA_DAMAGE_CHECKPOINT | MSigDB lists | REACTOME_P53_INDEPENDENT_G1_S_DNA_DAMAGE_CHECKPOINT | 48 | 15 | 17377 | 2626 |
PSMD2,PSMD1,PSMA6,PSMA8,RPS27A,PSMD8,PSMD3,PSMB7,PSMA1,CHEK2,PSMB9,PSMD9,PSMC1,PSMB3,PSMC4 |
| 3.656e-03 | -5.61 | GO_TRANSLATION_INITIATION_FACTOR_ACTIVITY | MSigDB lists | GO_TRANSLATION_INITIATION_FACTOR_ACTIVITY | 48 | 15 | 17377 | 2626 |
EIF3K,EIF3L,EIF2S2,DHX29,EIF3D,EIF2D,EIF2A,EIF5,EIF1B,EIF4G2,EIF4H,EIF3G,EIF3H,EIF3A,MCTS1 |
| 3.674e-03 | -5.61 | SASSON_RESPONSE_TO_GONADOTROPHINS_DN | MSigDB lists | SASSON_RESPONSE_TO_GONADOTROPHINS_DN | 86 | 23 | 17377 | 2626 |
MAPRE2,TLK1,MAP4K4,EZR,SMARCA4,RANGAP1,PAWR,CYFIP2,MAPK14,BECN1,ITGB5,CFLAR,PI4K2A,ATP2A2,MBD2,ADCY9,MAPK6,STAT1,PPP3R1,CAPZA1,DAPK1,ADCY7,SMARCD1 |
| 3.679e-03 | -5.61 | PRKAA1 (protein kinase AMP-activated catalytic subunit alpha 1) | protein interactions | 5562 | 128 | 33 | 17029 | 2761 |
PRKAB1,TSC2,RAF1,CUTA,INO80E,SND1,EPM2A,EEF2K,PHC2,PA2G4,DDA1,PHKG2,ABI1,DVL2,SRPK2,CDC37,RPL35,ASPM,USP10,MCL1,DCLRE1C,MCM2,MARK2,SUPT16H,RAD54B,PPP2CA,HSPA4,GOLGA2,L3MBTL3,CAB39,FKBP5,YWHAZ,STK11 |
| 3.679e-03 | -5.61 | ACTN4 (actinin alpha 4) | protein interactions | 81 | 128 | 33 | 17029 | 2761 |
MAPRE1,TXN,MYH9,MEF2A,GNB2,CDC73,MYEF2,PSMA6,SHC1,HUWE1,UCHL5,HDAC7,PTPN11,CYC1,CAMK2G,IDH3A,CAPZA2,MCFD2,MCM2,ANLN,ISG15,UBTF,AHNAK,HGS,PDLIM1,MYO18A,ITGB1,STAT1,KPNA2,CD81,COIL,POT1,CDKN2A |
| 3.679e-03 | -5.61 | SENESE_HDAC2_TARGETS_UP | MSigDB lists | SENESE_HDAC2_TARGETS_UP | 106 | 27 | 17377 | 2626 |
TNFAIP3,COPA,APH1A,DHX9,CREBL2,MCL1,BCLAF1,PLEC,CDC42SE2,RPL27A,CBFB,SCYL2,TFRC,SUPT16H,MLX,CDC27,DUS3L,UEVLD,TIMM17A,SNAP23,IL6ST,ATP13A3,ITGB1,C4orf46,SLC16A1,LMAN1,DDX42 |
| 3.681e-03 | -5.60 | NCKAP5L (NCK associated protein 5 like) | protein interactions | 57701 | 58 | 18 | 17029 | 2761 |
CCDC93,MAX,RPRD1A,RCOR1,NUF2,CNTROB,PSMD9,GIT2,HMG20A,OIP5,CDKN2AIPNL,PCM1,GRIPAP1,RABGAP1L,ODF2,ARNTL,CEP63,PTPRK |
| 3.681e-03 | -5.60 | DPY30 (dpy-30, histone methyltransferase complex regulatory subunit) | protein interactions | 84661 | 58 | 18 | 17029 | 2761 |
ZNF207,UNK,CXXC1,KLC1,WDR82,PRPF3,BRCA1,CHMP2B,KMT2C,WDR5,MATR3,FANCI,BANF1,MEA1,NUP153,PSMC1,MTPN,HDAC2 |
| 3.681e-03 | -5.60 | SLC33A1 (solute carrier family 33 member 1) | protein interactions | 9197 | 58 | 18 | 17029 | 2761 |
RAB14,IMMT,RBM42,TRIR,TAP1,MKI67,TMEM216,MAT2A,EVC2,SNUPN,ATP2A2,NCLN,ATP5F1A,TAGLN2,ECPAS,ZNF598,EEF1D,PDF |
| 3.681e-03 | -5.60 | DRG1 (developmentally regulated GTP binding protein 1) | protein interactions | 4733 | 58 | 18 | 17029 | 2761 |
STAU1,CYLD,SARNP,RWDD1,KIF23,BRCA1,SEPT7,UBE2I,SH3GLB1,CAND1,PHC2,CDK5,SUB1,PHKG2,COIL,ZC3HAV1,SRPK2,CDC5L |
| 3.704e-03 | -5.60 | V$GATA2_01 | MSigDB lists | V$GATA2_01 | 101 | 26 | 17377 | 2626 |
SP3,PLXNC1,REPS2,RPL8,FKBP2,SYMPK,CNOT3,PHF6,NCDN,KRIT1,MCTS1,UBTF,GNAS,VEZF1,VASP,SYNCRIP,KLHL5,CDC27,ZNRF2,DPYSL2,OAZ2,ZNF335,MPV17,CAPZA1,PCYT2,ATXN7L2 |
| 3.704e-03 | -5.60 | GO_GLYCOSYL_COMPOUND_BIOSYNTHETIC_PROCESS | MSigDB lists | GO_GLYCOSYL_COMPOUND_BIOSYNTHETIC_PROCESS | 91 | 24 | 17377 | 2626 |
TGFB1,PPCS,TK1,GUK1,AMD1,UCK2,ATP6V0A1,UCK1,ADSL,DCTD,SLC35B2,MAT2A,STOML2,MAT2B,ADSS,DCK,DUT,TYW5,PPCDC,ATP6V0A2,IMPDH1,UPRT,SLC26A2,PDCL3 |
| 3.704e-03 | -5.60 | GAGACTG,MIR-452 | MSigDB lists | GAGACTG,MIR-452 | 91 | 24 | 17377 | 2626 |
TCF12,SNX27,PPP1R12A,DYNLL1,FAM53C,LDB1,UTP15,CADM1,RHOT1,DOCK11,ZFAND5,FOXO3,DHX57,SH3GLB1,PAIP2,PPP2CA,SYNCRIP,MTMR4,RAB35,PPM1G,MAPK6,OGT,AXIN2,ABCC5 |
| 3.705e-03 | -5.60 | GSE17721_POLYIC_VS_CPG_4H_BMDC_DN | MSigDB lists | GSE17721_POLYIC_VS_CPG_4H_BMDC_DN | 190 | 43 | 17377 | 2626 |
TMED7,PIGM,UBE2E2,PKP4,SARNP,GMFG,RRP15,TM9SF4,RAB11B,DHPS,FAM76A,DHX8,CBLL1,CDK11B,UBE2I,WDR48,ABHD16A,MRPL50,LYAR,RRN3,C18orf32,MDM2,NUS1,TIMM23,RALB,SSBP3,BUD31,LRRC59,ACSL5,ADAM17,TNFAIP3,RDH10,ATP2C1,RFFL,KCNQ1,HSPA1B,SRSF1,SMAD2,SEL1L,ITGB1,LY75,CHID1,PDF |
| 3.705e-03 | -5.60 | GSE17301_IFNA2_VS_IFNA2_AND_ACD3_ACD28_STIM_CD8_TCELL_UP | MSigDB lists | GSE17301_IFNA2_VS_IFNA2_AND_ACD3_ACD28_STIM_CD8_TCELL_UP | 190 | 43 | 17377 | 2626 |
DDX58,UBL3,GNPDA1,KLHL21,RPS6KA1,BTN3A1,EXT2,PCYOX1L,GNS,MLX,ZCCHC2,FUT8,ZNF200,SEPT11,TTC17,PLCL2,OGG1,ZNF189,BAK1,ARHGAP17,CYTH1,COQ10B,LRBA,WIPF1,ATXN1,EMP3,EDEM2,POLG2,PDE3B,RAB5B,RAB22A,OPTN,TRAM2,GOLGA4,MAGT1,CTBS,ARAP1,MLYCD,QRSL1,KLHDC4,TRIM32,NAA60,ZC3HAV1 |
| 3.705e-03 | -5.60 | GSE26343_UNSTIM_VS_LPS_STIM_NFAT5_KO_MACROPHAGE_UP | MSigDB lists | GSE26343_UNSTIM_VS_LPS_STIM_NFAT5_KO_MACROPHAGE_UP | 190 | 43 | 17377 | 2626 |
HIVEP3,HSPH1,URB2,MED13L,NKRF,SLC35B1,BRIX1,PCBP1,CMTM6,CHD1,KIAA1147,CFLAR,IRF4,UBXN2A,INPP5A,UTP18,ATIC,ORAI1,S100A6,NUDC,COPS8,PLK3,UBQLN4,GTF3C6,HEMK1,ZNF202,WDR1,NOL8,NSUN2,UTP15,PCGF6,USP10,LUC7L,PICALM,EML4,TARS,USP36,FAS,UAP1,ZC3H7B,ACLY,LTA4H,PDF |
| 3.705e-03 | -5.60 | GSE22103_UNSTIM_VS_GMCSF_AND_IFNG_STIM_NEUTROPHIL_DN | MSigDB lists | GSE22103_UNSTIM_VS_GMCSF_AND_IFNG_STIM_NEUTROPHIL_DN | 190 | 43 | 17377 | 2626 |
CLSPN,CHD1L,PTTG1,COPE,CENPF,JMJD6,HAUS4,NENF,NANS,SLC20A1,NDUFS7,HDDC2,C12orf10,SH3BP1,RINL,MCM5,MSH2,ABCD1,KNTC1,IMPA2,TMEM160,CARS2,ORAI2,RPL35,CKAP2L,CDCA2,MPG,KRTCAP2,SPPL2B,MYO1F,RPL36,XRCC5,MRPL2,ALDH3B1,TIMM13,PRMT7,AP1S1,GPI,RUVBL2,FAU,EHD4,UBE2C,CCNB2 |
| 3.705e-03 | -5.60 | GSE43955_10H_VS_60H_ACT_CD4_TCELL_UP | MSigDB lists | GSE43955_10H_VS_60H_ACT_CD4_TCELL_UP | 190 | 43 | 17377 | 2626 |
SART1,EWSR1,PRKCSH,TRIM11,EIF3D,MOGS,NUP54,SMARCA4,NANS,DNAJB1,BCAP31,RPA2,APLP2,TBC1D22A,AP1M1,ANXA5,AQR,ALDH9A1,MLST8,ERCC1,LARS,DEAF1,FOXK1,HARS,RNASEH2C,PSPC1,ANAPC2,MAP7D1,SMC2,MPG,GFER,PRDX1,NEU1,PPP2R5A,ZHX1,ERGIC3,ASNA1,IDH3B,NDE1,RRS1,CD81,EYA2,FUBP1 |
| 3.711e-03 | -5.60 | DSP (desmoplakin) | protein interactions | 1832 | 104 | 28 | 17029 | 2761 |
TELO2,PKP4,CYLD,CASP6,DYNLL1,CUL3,BRCA1,CNTROB,MCM2,SEC16A,PRKACA,PSEN1,RAB5B,SDHA,CDC73,RPA1,CAND1,RPA2,PCM1,JAK1,PTEN,UCHL5,MCM5,TARDBP,NAP1L4,TECR,CDK2,CDC5L |
| 3.712e-03 | -5.60 | intracellular signal transduction | biological process | GO:0035556 | 1663 | 291 | 17256 | 2622 |
RAB14,TSC2,MAP3K7CL,PRKCSH,TMEM109,CUL1,CCNB1,PARK7,CALM2,PSMD1,RAB4A,FNIP2,MAST2,MOB1A,PLCL2,DNMT1,MLST8,CDC5L,PLK3,BAK1,PGAP2,RHOBTB3,NRAS,AKT2,ARHGAP45,TOPORS,MCL1,RAB22A,RAB2B,KRIT1,MAP3K4,MKNK1,SMAD2,WAS,RPS27A,PSMD8,LIMK1,AXIN1,OGT,TFDP2,SMAD1,E2F2,ZMAT3,DDX58,WSB2,RHOC,VAV2,PRKAA1,RAB23,CYCS,PSEN1,PSMD9,CNOT3,JMY,NDUFS4,RTKN,TFAP4,INPP5A,MSH2,DAPK1,PIKFYVE,GNAI2,PHKG2,SOCS5,CYFIP1,MAPKAPK3,ERO1A,USP10,ADRB2,RIT1,MAP2K2,RHOB,PSMB3,PPP3R1,CNOT6,MAP3K5,CDK2,NRBP1,ALS2,CDKN2A,RHOG,KARS,RAB11B,RPS6KA1,RAF1,RAC1,BCL2L1,PRKACA,STMN1,MOAP1,CRKL,RAB21,PRKD3,CCNA2,ATP2A2,SHC1,SP100,RALB,ADCY9,SOCS6,CDKN1B,TP53BP2,CEP63,CFL1,ADCY7,SHOC2,KAT7,MAP4K4,TAOK1,CUL3,ASB13,RAB1A,PSMB9,TRIM28,ERC1,SOCS7,PPP2CA,HINT1,JAK1,RAB24,GUCY1B1,HIPK2,STAT1,TICAM1,PPP5C,RHEBL1,DEPDC1,ZFP91,CCM2,BABAM1,FLOT1,BRAP,AKT1S1,IFT27,FOXO3,RAB11A,MAD2L2,PSMD2,PDCD10,PTEN,CENPJ,ARHGEF1,GTSE1,CREB1,MAP3K14,CNOT6L,UBE2M,MSH6,SPTAN1,PDPK1,PPP3CA,TNFAIP3,NET1,RFXANK,RABIF,ZP3,RHOT1,MARK2,SH3BP5,GNA12,GPS2,MAPK6,TFDP1,PML,AEN,DDX5,RGL1,NPHP4,NF1,SIRT2,MAPK14,BIRC2,PRNP,DLG5,RAB8A,PCNA,RAP1A,CDC42,RAB35,PIK3R2,AKR1B1,ASB6,CARM1,SRPK2,COPS8,PLK1,RBX1,TLK1,EZR,UBE2V1,BRCA1,SOX4,RAB5B,STK17B,E2F4,SOCS4,CAB39,STK11,DVL1,ROCK1,CHEK2,PSMC1,LAMTOR3,CDIP1,MEF2A,RACGAP1,NCKAP1,RAB6A,PPP3CB,DOCK11,CNOT11,RAPGEF6,APOPT1,DTL,RB1,NFATC3,XPA,CTR9,MDFIC,BCL2,NUDT4,PSMA1,MAP4K3,KRAS,STYXL1,DAPK3,PSMC4,MASTL,GNAS,NLRC5,SIAH2,MYO9A,UNC13C,WASF2,CYLD,FOXM1,RRAGC,IRF3,LYN,BCAP31,VAV1,PDK2,MDM2,PSMA6,BABAM2,DVL2,HTRA2,CHP1,PRPF19,BIRC3,PSMA8,BTG2,RAB7A,PSMB7,NFATC2,AZI2,TOLLIP,DNAJC10,TAB2,PSMD3,STK38,MAPK1,SMAD4,ABCA1,MIF,SH2D3A,ARFIP2,MYO9B,FGFR3,TANK,ARHGEF2,ANP32A,STAT3,CAMK2G,TGFB1,PPP1R9B,RHOA,PRKDC,ARHGEF12,MEN1,RHOT2,MAPK3,CNOT9,RAB18,NEK1,ELMO1,KBTBD7,E2F1,PKD2,HRAS,IFI16 |
| 3.713e-03 | -5.60 | REACTOME_SIGNALING_BY_ERBB2 | MSigDB lists | REACTOME_SIGNALING_BY_ERBB2 | 96 | 25 | 17377 | 2626 |
PDPK1,NRAS,TSC2,AKT2,RAF1,PRKAR1B,KRAS,AKT1S1,PRKACA,FOXO3,MAP2K2,MAPK3,CALM2,MDM2,SHC1,PTEN,RPS27A,ADCY9,CDKN1B,CREB1,MAPK1,HRAS,CDC37,ADCY7,MLST8 |
| 3.713e-03 | -5.60 | KEGG_PYRIMIDINE_METABOLISM | MSigDB lists | KEGG_PYRIMIDINE_METABOLISM | 96 | 25 | 17377 | 2626 |
POLA2,TK1,POLR2I,POLR2G,POLR2L,PRIM2,POLR2K,UCK2,RRM1,POLR2D,UCK1,POLR3GL,RRM2,DCTD,POLR3K,POLR2A,PRIM1,POLE,POLR2J,DCK,DUT,CANT1,UPRT,POLR1B,ZNRD1 |
| 3.714e-03 | -5.60 | PTPRO (protein tyrosine phosphatase, receptor type O) | protein interactions | 5800 | 76 | 22 | 17029 | 2761 |
PPIB,GOLIM4,PRKCSH,MAN1B1,TMX4,SDF2L1,APP,HLA-A,HLA-B,TMED10,PGRMC1,SEL1L,SIL1,YWHAZ,SPCS3,DNAJC30,LMAN1,PDIA6,CLN6,NGLY1,TMX1,TMED2 |
| 3.714e-03 | -5.60 | MARS (methionyl-tRNA synthetase) | protein interactions | 4141 | 76 | 22 | 17029 | 2761 |
KARS,PRKAB1,LARS,CYLD,HARS,TRMT6,CUL3,CUL1,BRCA1,MCM2,RPL27A,MAPK14,EPRS,IARS,HUWE1,MAFK,QARS,ZNF746,TXLNA,ACAT1,CRY2,NAA20 |
| 3.714e-03 | -5.60 | SAT1 (spermidine/spermine N1-acetyltransferase 1) | protein interactions | 6303 | 76 | 22 | 17029 | 2761 |
UBE2D3,MRPL9,KAT7,EIF3D,C19orf25,CSNK2A1,VKORC1,DDX39A,RBM17,VASP,CHD3,ZHX1,MTA1,PLGRKT,RPLP1,SARAF,COPS6,B4GALT3,FAM86C1,SAT2,FTSJ3,LUC7L2 |
| 3.730e-03 | -5.59 | PILON_KLF1_TARGETS_UP | MSigDB lists | PILON_KLF1_TARGETS_UP | 472 | 93 | 17377 | 2626 |
ZNF207,CCNC,PIGM,CYLD,AGRN,REPS2,MAGED1,ANK3,OLA1,AGFG1,C2orf49,BECN1,MAPK14,ANKRD39,NAPG,MDM2,ZNF639,LPIN2,SLC44A1,NSFL1C,MARCH2,TMEM9,DRAM2,SHOC2,CLCN3,MIOS,HARS,TLK1,SLBP,ZFAND5,DHX57,SUPT16H,KIF2A,PON2,RAD18,HIPK2,FTSJ1,RBMS1,ACTB,CLU,OSGEPL1,SLC22A23,PITRM1,ABCA1,CWC25,KIF3B,GCLM,PIGN,MZT1,RHOC,DNAJB2,TRIO,ANKH,SDC2,NUP54,PCSK7,CHAC2,RAB6A,CSNK1A1,ASXL2,FOXO3,HMG20A,HLA-A,XPR1,SRXN1,C1GALT1,KLHL20,HUWE1,KNTC1,GTF2H2,N4BP2,LUC7L2,VOPP1,ELL2,MIER1,ITM2A,FBXO9,EIF2AK1,SRSF5,PICALM,ZFR,PTPRF,NAP1L1,MTHFD2,KPNA1,MAGT1,CSNK1G1,PTAR1,FAM126A,PKD2,PPP6R3,WDR91,SNX14 |
| 3.736e-03 | -5.59 | GSE21546_WT_VS_SAP1A_KO_DP_THYMOCYTES_DN | MSigDB lists | GSE21546_WT_VS_SAP1A_KO_DP_THYMOCYTES_DN | 158 | 37 | 17377 | 2626 |
KLHL21,WDYHV1,POC1A,RPS6KA1,TCF3,CERK,SUMF1,NIPA2,RGS2,AHCTF1,ZNF473,TIMM23,MCM5,PPP4R1,PPP6C,TRA2B,SLC26A2,CABLES2,SMARCE1,SNX8,PPIF,FAM172A,HARS,ZMYND11,WDR1,POLR2D,BCLAF1,UBE4B,ODC1,EIF4H,CBFB,NMT2,TMEM168,WNT5B,SEL1L,BRD9,ATMIN |
| 3.737e-03 | -5.59 | positive regulation of protein acetylation | biological process | GO:1901985 | 39 | 13 | 17256 | 2622 |
TERF2IP,TGFB1,KAT2A,KAT7,ARNTL,PRKAA1,WBP2,BRD7,RUVBL2,BRCA1,SOX4,SMAD4,MAPK3 |
| 3.737e-03 | -5.59 | regulation of autophagy of mitochondrion | biological process | GO:1903146 | 39 | 13 | 17256 | 2622 |
ATP5IF1,TSC2,TIGAR,FBXO7,GBA,VDAC1,SMURF1,PARK7,HTRA2,USP36,OPTN,CDC37,MFN2 |
| 3.737e-03 | -5.59 | CSNK1A1 (casein kinase 1 alpha 1) | protein interactions | 1452 | 133 | 34 | 17029 | 2761 |
DYNLL1,SEC16A,GNB2,CREM,RPA2,ZBTB21,NFATC3,MDM2,MZT2A,KIF13B,TTC9C,GTSE1,USP34,ERF,DENND4C,LRP5,FADD,GIGYF1,RPA1,PPP2CA,HSPA4,PCM1,PPP2R5A,AXIN1,MYO18A,E2F1,FAM83D,ACTB,YWHAZ,KPNA2,HMGB2,MZT2B,CSNK1D,FAM83G |
| 3.739e-03 | -5.59 | Znf_PHD-finger | interpro domains | IPR019787 | 77 | 21 | 18492 | 2768 |
PHF10,KMT2E,BAZ2A,PHF23,PHRF1,CXXC1,ZMYND11,NSD3,DIDO1,KMT2C,TRIM28,SP100,BRPF3,KDM2A,CHD3,PHF14,UHRF2,KMT2B,BAZ1B,INTS12,FBXL19 |
| 3.745e-03 | -5.59 | TUBG1 (tubulin gamma 1) | protein interactions | 7283 | 239 | 55 | 17029 | 2761 |
RPS15,RPS2,PDCD6IP,MZT1,TMUB1,AGRN,RPLP2,OLA1,RACGAP1,COX4I1,DNAJB1,PRKACA,HAUS2,APP,TUBGCP2,DTL,RPN1,NAPG,MZT2A,CCP110,RPL17,CENPJ,KIF14,DDA1,HADHB,RNF19A,CAMK2G,PDCL3,TIMM50,CDC5L,AMPD2,PLK1,CCT2,DPM1,RPS10,RPL6,TUBGCP5,PRPF3,BRCA1,H2AFV,CCT8,RPS9,MAGED2,KEAP1,TIMM13,HSPA4,PSMD8,RPS14,YWHAZ,ACTB,NDE1,CDK2,YWHAH,MZT2B,TUBB |
| 3.745e-03 | -5.59 | DNA Damage Response | WikiPathways | WP707 | 69 | 20 | 5312 | 837 |
PRKDC,GADD45G,TLK1,CYCS,BRCA1,CCNB1,FAS,CDK5,RPA2,RB1,MDM2,GADD45B,E2F1,PML,H2AFX,CDKN1B,CHEK2,CREB1,CCNB2,CDK2 |
| 3.746e-03 | -5.59 | negative regulation of protein phosphorylation | biological process | GO:0001933 | 435 | 87 | 17256 | 2622 |
ZBED3,FGFR1OP,ASH1L,GGNBP2,TSC2,FOXM1,NF1,FAM129A,PPP1R15B,SIRT2,CCNB1,LYN,DUSP22,PARK7,PRNP,TERF2IP,CALM2,CDKN2C,PIN1,PIK3R2,SOCS6,CDKN1B,TARDBP,GPD1L,STRAP,CTDSP2,CHP1,PLK1,SNX25,BAK1,NCK1,PBK,GMFB,EZR,LRP5,DNAJA1,EIF3A,SOCS7,PPP2CA,HHEX,DNAJC10,CORO1C,STK38,GADD45B,SOCS4,DVL1,PPP5C,ARRB2,SMAD4,PDCD4,PARD3,HSPH1,GMFG,CIB1,AKT1S1,RGS2,PSEN1,VPS25,PTPN2,TFAP4,RB1,PTEN,FBXO7,DUS2,H2AFY,MVP,SOCS5,PDPK1,TGFB1,TNFAIP3,PRKDC,ZMYND11,GBA,PRKAR1B,MEN1,LEMD2,SH3BP5,MBIP,GPS2,DUSP3,CSK,QARS,NUP62,NR2F2,IGBP1,HIPK3,CDKN2A |
| 3.749e-03 | -5.59 | GO_TRANSLATION_PREINITIATION_COMPLEX | MSigDB lists | GO_TRANSLATION_PREINITIATION_COMPLEX | 15 | 7 | 17377 | 2626 |
EIF3K,EIF3L,EIF3G,DHX29,EIF3D,EIF3A,EIF3H |
| 3.749e-03 | -5.59 | MODULE_133 | MSigDB lists | MODULE_133 | 15 | 7 | 17377 | 2626 |
FARSA,EPRS,KARS,IARS,HARS,QARS,TARS |
| 3.749e-03 | -5.59 | MODULE_160 | MSigDB lists | MODULE_160 | 15 | 7 | 17377 | 2626 |
KHSRP,EPRS,KARS,IARS,HARS,QARS,TARS |
| 3.749e-03 | -5.59 | GO_REGULATION_OF_ARP2_3_COMPLEX_MEDIATED_ACTIN_NUCLEATION | MSigDB lists | GO_REGULATION_OF_ARP2_3_COMPLEX_MEDIATED_ACTIN_NUCLEATION | 15 | 7 | 17377 | 2626 |
ARFIP2,CYFIP1,WAS,ARF1,NCKAP1,GMFG,GMFB |
| 3.749e-03 | -5.59 | GO_DNA_DAMAGE_RESPONSE_SIGNAL_TRANSDUCTION_RESULTING_IN_TRANSCRIPTION | MSigDB lists | GO_DNA_DAMAGE_RESPONSE_SIGNAL_TRANSDUCTION_RESULTING_IN_TRANSCRIPTION | 15 | 7 | 17377 | 2626 |
TFAP4,BRCA1,SP100,FOXM1,HIPK2,MAD2L2,RBM38 |
| 3.749e-03 | -5.59 | GSE25088_WT_VS_STAT6_KO_MACROPHAGE_ROSIGLITAZONE_STIM_UP | MSigDB lists | GSE25088_WT_VS_STAT6_KO_MACROPHAGE_ROSIGLITAZONE_STIM_UP | 174 | 40 | 17377 | 2626 |
RPS2,URB2,UBXN1,NACA,BABAM1,VPS45,GTF3A,SEC16A,SLC25A37,PAPOLA,INPP5A,TMEM99,RPF2,TTC3,SLC26A2,OSTC,NDUFA3,VPS13B,ABHD2,MLEC,POLR2G,RDH10,RPL8,ATXN1,NUTF2,CDC23,NMT2,GALNT2,QARS,TPP2,PPA2,IARS2,SPCS3,RBPJ,GPI,B4GALT3,ZMIZ1,RNF14,RTN3,NUMB |
| 3.749e-03 | -5.59 | GSE9960_GRAM_NEG_VS_GRAM_POS_SEPSIS_PBMC_UP | MSigDB lists | GSE9960_GRAM_NEG_VS_GRAM_POS_SEPSIS_PBMC_UP | 174 | 40 | 17377 | 2626 |
CYTIP,PDCD6IP,SCAMP3,UGP2,AGRN,TRIP10,PPP1R15B,VTI1A,CUL1,ADPGK,RGS1,CFLAR,RAB8A,ITGB8,TNFAIP8,ZNRF2,MCM5,DDA1,TAGLN2,STAT3,PPP1R18,ETV3,TMEM39A,NET1,ANKRD33B,COQ10B,LYRM1,MIER1,PLEKHM3,PEF1,ALKBH6,C1orf122,TMEM41A,STAT1,PITPNA,TICAM1,ST3GAL2,NDE1,PARP10,TUBB |
| 3.751e-03 | -5.59 | Kinesin_motor_dom | interpro domains | IPR001752 | 44 | 14 | 18492 | 2768 |
KIF5B,KIFC1,KIF2A,KIF3B,STARD9,KIF18A,KIF18B,KIF14,KIF13B,KIF15,KIF23,KIF22,KIF2C,KIF11 |
| 3.759e-03 | -5.58 | Dynll1 (dynein light chain LC8-type 1) | protein interactions | 56455 | 67 | 20 | 17029 | 2761 |
MOB4,AGGF1,FAM172A,STRIP1,DYNLL1,TLK1,STRN4,RCOR1,RCOR3,SPAG5,ZMYM3,MASTL,PPP2CA,NRF1,PDCD10,FAM83D,GLCCI1,HDAC2,DYNC1LI2,MORC3 |
| 3.759e-03 | -5.58 | FANCI (Fanconi anemia complementation group I) | protein interactions | 55215 | 67 | 20 | 17029 | 2761 |
MAGED1,CUL3,PTP4A3,MCM2,APP,FANCI,WDR48,USP36,FANCL,GSTK1,NEK6,RAD18,DDOST,TIMM23,DGCR8,MCM5,PELO,UHRF2,CLN3,CDC5L |
| 3.759e-03 | -5.58 | G6PD (glucose-6-phosphate dehydrogenase) | protein interactions | 2539 | 67 | 20 | 17029 | 2761 |
PPP1R2,TSTA3,HARS,ARMT1,UBE2V1,MCM2,EIF4H,CDC73,MAT2B,GNS,DUT,RAD23B,CTR9,YWHAZ,PDXK,EIF5,PGAM1,YWHAH,CAPN1,LDHB |
| 3.759e-03 | -5.58 | ERGIC3 (ERGIC and golgi 3) | protein interactions | 51614 | 67 | 20 | 17029 | 2761 |
SLC30A9,CLPTM1,NDC1,ANKRD13D,TMEM184B,PXMP2,SPPL2B,WRB,SFXN5,SSR1,ALG3,VMP1,TIMM29,BDH1,ERGIC3,PARL,SLC38A10,SLC26A2,NR2F2,CHPT1 |
| 3.759e-03 | -5.58 | PLEKHF2 (pleckstrin homology and FYVE domain containing 2) | protein interactions | 79666 | 67 | 20 | 17029 | 2761 |
MAX,GPBP1L1,TSC22D3,DRAP1,UBE2Z,CHIC2,PRPSAP1,GFER,APPL1,APP,MEAF6,USF1,MBIP,FBXO28,TNFAIP8,L3MBTL3,DUT,RTN3,FRMD8,CGGBP1 |
| 3.759e-03 | -5.58 | POLDIP2 (DNA polymerase delta interacting protein 2) | protein interactions | 26073 | 67 | 20 | 17029 | 2761 |
PDPK1,COQ8A,COQ10B,LACTB,CUL3,CHCHD2,NDUFA4,NFATC2,FAM136A,XPNPEP3,MCM2,LYRM2,APP,MAD2L2,PCNA,COQ4,PTEN,MTMR4,ATP5F1A,PTPDC1 |
| 3.759e-03 | -5.58 | RARS (arginyl-tRNA synthetase) | protein interactions | 5917 | 67 | 20 | 17029 | 2761 |
KARS,LARS,STAU1,CYLD,CUL3,RNPS1,CUL1,BRCA1,DNAJA1,MCM2,CDC73,TUBGCP2,EPRS,MDM2,C1orf131,IARS,QARS,ASNA1,TFG,TUBB |
| 3.759e-03 | -5.58 | DUSP23 (dual specificity phosphatase 23) | protein interactions | 54935 | 67 | 20 | 17029 | 2761 |
PRRC2A,SCYL1,RAC1,CIRBP,RPL8,ASB13,AP3S1,DUSP22,EDRF1,HDDC2,SSR1,SUGP1,C1orf131,CTNNBL1,SHC1,DBI,ZNF746,KBTBD7,FN3KRP,UBE2M |
| 3.759e-03 | -5.58 | posttranscriptional regulation of gene expression | biological process | GO:0010608 | 692 | 131 | 17256 | 2622 |
FAM129A,PPP1R15B,RBM8A,DNAJC24,YTHDF3,EIF1B,MAPK14,RBM4,PABPC4,PA2G4,PSMD1,EIF4A3,METTL14,EIF5,MTPN,CDC37,EXOSC6,NCK1,AKT2,SOX4,PRKRA,GEMIN5,MKNK1,EIF4ENIF1,SMAD2,RPS27A,PSMD8,RPS14,RNASEL,SMAD1,PSMC1,ZNF598,DHX9,TIA1,EIF2AK4,THRAP3,RGS2,PSMD9,PARN,CNOT11,METTL3,SRRT,CNOT3,EXOSC7,MEX3C,DAPK1,YBX1,RBM3,GLE1,PABPC1,NSUN4,EIF5A,CYFIP1,PSMA1,EIF2AK1,EXOSC9,EIF2A,FXR1,CYFIP2,EIF4H,EIF4G2,MATR3,DAPK3,PSMB3,PSMC4,TSC1,EPRS,SYNCRIP,YWHAZ,CNOT6,TCOF1,TOB1,RNF139,SARNP,RPS6KA1,EIF3D,APP,PAIP1,PAIP2,HNRNPA2B1,PSMA6,EXOSC1,MRPS27,TARDBP,POLR2G,PSMA8,CDC123,BTG2,CIRBP,PSMB7,POLR2D,RPL38,PSMB9,SERP1,RPS9,EIF3H,EIF3K,HNRNPR,DGCR8,PSMD3,MAPK1,UNK,MIF4GD,HABP4,AGO2,SECISBP2,FOXO3,TUT4,FASTKD3,PSMD2,AXIN2,ANP32A,LTN1,DCP1A,CNOT6L,STAT3,SAMD4B,YTHDC1,COA3,RHOA,ILF3,TBRG4,MAPK3,CNOT9,UPF1,ZC3H7B,E2F1,LRPPRC,KHSRP,PURA,CPEB2 |
| 3.760e-03 | -5.58 | PID_MYC_REPRESS_PATHWAY | MSigDB lists | PID_MYC_REPRESS_PATHWAY | 62 | 18 | 17377 | 2626 |
MAX,DNMT3A,TSC2,BRCA1,MXD4,FOXO3,CFLAR,CSDE1,SMAD2,RBL1,ITGB1,CDKN1B,BCL2,CLU,CREB1,GTF2H2,SMAD4,ALDH9A1 |
| 3.760e-03 | -5.58 | PID_TRKR_PATHWAY | MSigDB lists | PID_TRKR_PATHWAY | 62 | 18 | 17377 | 2626 |
RHOG,RHOA,NRAS,MAGED1,RAC1,KRAS,RIT1,MAPK3,CRKL,RAP1A,CDC42,SHC1,ELMO1,PTPN11,EHD4,STAT3,MAPK1,HRAS |
| 3.760e-03 | -5.58 | chr7p22 | MSigDB lists | chr7p22 | 62 | 18 | 17377 | 2626 |
SNX8,MIOS,FOXK1,ZNF316,CCZ1,RAC1,USP42,PRKAR1B,PMS2,EIF2AK1,GNA12,INTS1,MAFK,CCZ1B,WIPI2,TNRC18,GLCCI1,C7orf26 |
| 3.760e-03 | -5.58 | GO_PEPTIDE_N_ACETYLTRANSFERASE_ACTIVITY | MSigDB lists | GO_PEPTIDE_N_ACETYLTRANSFERASE_ACTIVITY | 62 | 18 | 17377 | 2626 |
KAT2A,KAT7,ELP4,EDF1,TAF6L,USP22,WDR5,SUPT7L,SAP130,OGT,NAA50,TAF5L,TAF12,NCOA1,NAA20,ATF2,NAA60,NCOA2 |
| 3.770e-03 | -5.58 | cell cycle arrest | biological process | GO:0007050 | 152 | 36 | 17256 | 2622 |
PRKAB1,TSC2,KMT2E,PRKAA1,LAMTOR3,CUL1,RRAGC,EIF2AK4,NOTCH2,JMY,PRNP,CDKN2C,PA2G4,RB1,MSH2,CDKN1B,MCPH1,MLST8,TGFB1,PPP1R9B,CDC123,CUL3,TBRG4,EIF4G2,RHEB,MFN2,TSC1,LAMTOR4,PPM1G,PML,CAB39,STK11,PKD2,GAS2,HRAS,CDKN2A |
| 3.773e-03 | -5.58 | GO_TRANSFERASE_ACTIVITY_TRANSFERRING_ACYL_GROUPS_OTHER_THAN_AMINO_ACYL_GROUPS | MSigDB lists | GO_TRANSFERASE_ACTIVITY_TRANSFERRING_ACYL_GROUPS_OTHER_THAN_AMINO_ACYL_GROUPS | 201 | 45 | 17377 | 2626 |
NAT14,NAT9,GNPNAT1,ZDHHC8,AGPAT1,AGPAT3,TAF6L,WDR5,SUPT7L,LCLAT1,SAP130,CRAT,ZDHHC13,NAA50,HADHB,TAF5L,SPTSSA,ATF2,LPCAT1,SMARCE1,NCOA2,ELOVL5,ZDHHC18,KAT2A,KAT7,ELP4,USP22,EDF1,TAZ,ZDHHC3,NMT2,ABHD5,AGPAT2,CERS6,LPCAT4,OGT,ACAT1,ZDHHC7,MBOAT1,NCOA1,TAF12,NAA20,OSGEPL1,SAT2,NAA60 |
| 3.780e-03 | -5.58 | regulation of ATPase activity | biological process | GO:0043462 | 76 | 21 | 17256 | 2622 |
PPIF,DNAJC2,ATP5IF1,DNAJB2,DYNLL1,TOR1AIP1,DHX9,DNAJC24,DNAJC9,TOR1AIP2,DNAJB1,DNAJA1,DNAJC10,TSC1,THADA,AHSA1,RAB4A,DNM2,SNRNP70,CHTOP,DNAL4 |
| 3.795e-03 | -5.57 | SYVN1 (synoviolin 1) | protein interactions | 84447 | 90 | 25 | 17029 | 2761 |
UBE2D3,USP7,TMUB1,ATXN3,ERLIN1,PSMB7,PSMA1,MYH9,UBE2Z,WBP1,SYVN1,FAM8A1,APP,PSMB3,HLA-A,DERL1,PSMD2,PSMD1,PSMA6,SEL1L,SARAF,ATF6,CLU,SVIP,FDFT1 |
| 3.795e-03 | -5.57 | NDUFS7 (NADH:ubiquinone oxidoreductase core subunit S7) | protein interactions | 374291 | 90 | 25 | 17029 | 2761 |
NDUFA5,NDUFV2,HEMK1,NDUFS1,NQO1,NDUFB6,TIMMDC1,MCCC1,NDUFA4,NDUFA7,RHOT2,GFM2,NDUFS7,ATPAF1,NDUFS4,NDUFV1,INTS1,FAM3C,NDUFA11,MPV17,IARS2,NDUFB9,NDUFS8,NDUFS5,ARRB2 |
| 3.796e-03 | -5.57 | endoplasmic reticulum-Golgi intermediate compartment membrane | cellular component | GO:0033116 | 68 | 19 | 18223 | 2701 |
TMED7,GORASP1,TAP1,TMED3,MCFD2,BCAP31,CD59,GOLGA2,SURF4,VMP1,TMED10,ERGIC3,TAP2,PIEZO1,SLC35C2,LMAN1,TMED2,CSNK1D,KDELR1 |
| 3.800e-03 | -5.57 | Formation of the ternary complex, and subsequently, the 43S complex | REACTOME pathways | R-HSA-72695 | 53 | 17 | 10287 | 1696 |
RPS15,EIF3L,RPS2,EIF3D,RPS10,RPS24,EIF3G,RPS9,RPSA,EIF3H,EIF3A,EIF3K,EIF2S2,RPS27A,RPS14,FAU,RPS26 |
| 3.809e-03 | -5.57 | GO_ORGANIC_CYCLIC_COMPOUND_CATABOLIC_PROCESS | MSigDB lists | GO_ORGANIC_CYCLIC_COMPOUND_CATABOLIC_PROCESS | 403 | 81 | 17377 | 2626 |
TRERF1,RPLP2,RBM8A,PAIP1,PABPC4,EDC3,RPL11,RPL23A,MBD4,CSDE1,EIF4A3,GOT2,DUT,EXOSC1,RNASEH2A,OGG1,ENPP4,RPL29,EXOSC6,RPL35,POLR2G,RPL38,POLR2D,RNPS1,RPS9,RPSA,PPP2CA,RPL37,HINT1,LSM6,RPS27A,RPS14,RPLP1,MLYCD,SCARB1,SMG9,FAU,RPS26,RPS15,RPS2,GSPT2,RPL15,THRAP3,EPHX2,PARN,CNOT3,NEIL2,PRPF18,PDXP,EXOSC7,RPL17,PPP1R8,PELO,DCP1A,AHCY,UPF2,RPL19,CNOT6L,PABPC1,RNASEH2C,RPL8,RPL6,RPS10,RPS24,EXOSC9,MPG,RPL27A,PDE3B,PATL1,RPL36,CAT,UPF1,KPNA1,RPL32,TATDN2,KHSRP,HMGB2,CNOT6,TATDN1,YWHAH,NUDT3 |
| 3.815e-03 | -5.57 | ATTCTTT,MIR-186 | MSigDB lists | ATTCTTT,MIR-186 | 256 | 55 | 17377 | 2626 |
INTS2,TMED7,SNX27,CAST,XIAP,CSNK2A1,ARGLU1,RAB6A,UBQLN2,PRPF39,EXT2,CSDE1,DLG5,APLP2,RAB21,NUS1,EIF2S2,PDCD10,CDC42,CAPZA1,PDS5B,TARDBP,PTGES3,AHCYL1,MTPN,PABPC1,NCOA2,TMED2,MOSPD1,CDC5L,SRPK2,SP3,NASP,RB1CC1,LRBA,MIER1,WIPF1,RABIF,SEPT7,MCFD2,ICMT,EIF3A,UPF1,ZHX1,OSBPL8,PARG,MAP4,PPM1G,LMBR1,BTF3,YY1,MAPK1,CPEB2,MRPL3,TOB1 |
| 3.818e-03 | -5.57 | GO_NITROGEN_COMPOUND_TRANSPORT | MSigDB lists | GO_NITROGEN_COMPOUND_TRANSPORT | 484 | 95 | 17377 | 2626 |
TOMM20,SARNP,NUP188,THOC1,NF1,RAB11B,RAF1,RBM8A,ALKBH5,TAP1,UBE2Q1,SLC29A1,AGFG1,SLC35B2,LYN,PARK7,CD320,HNRNPA2B1,SNUPN,AHCTF1,NUP210,EIF4A3,SRSF4,SLC44A1,NUP107,NUP153,TAP2,CHTOP,SLC35C2,ZC3H3,SEH1L,SRSF10,FYTTD1,NXT1,RNPS1,POLR2D,SLBP,SLC25A22,NUP155,SLC17A5,PPFIA3,BUD13,RAB1A,SLC25A5,RPSA,SRSF1,IWS1,HHEX,SMAD2,CLN3,ABCA1,AAAS,SLC25A33,NXT2,CDC40,SRSF6,MECP2,RAE1,FLOT1,NUP54,SLC25A12,SLC35B1,XPO7,PSEN1,NUP205,SLC25A36,SLC1A4,SLC38A5,SLC35B4,UPF2,SLC38A10,GLE1,MVP,SLC12A2,NUP85,SLC35A1,CAMK2G,MYO5A,ABCC1,EIF5A,SRSF11,SRSF5,DDX39A,TSC1,SLCO4A1,SLC19A1,UPF1,LTBP4,SLC38A7,SNAP23,LRPPRC,KHSRP,SLC25A19,NUP62,SRSF3 |
| 3.821e-03 | -5.57 | THOP1 (thimet oligopeptidase 1) | protein interactions | 7064 | 41 | 14 | 17029 | 2761 |
ADSS,C12orf10,PTMS,IDE,ANXA6,UAP1,DCK,WDR1,PPM1G,VAV2,STK11,TALDO1,PRKACA,CBX3 |
| 3.821e-03 | -5.57 | THOC6 (THO complex 6) | protein interactions | 79228 | 41 | 14 | 17029 | 2761 |
RPA2,SNRNP200,THOC1,ZCCHC8,PRKDC,SUZ12,SF3B6,EFTUD2,ZNF326,VDAC2,BCLAF1,ABI1,RPA1,SRSF10 |
| 3.821e-03 | -5.57 | SCAF11 (SR-related CTD associated factor 11) | protein interactions | 9169 | 41 | 14 | 17029 | 2761 |
MZT2A,MZT1,EID1,SRSF4,TUBGCP5,JMJD6,SRSF3,SNRNP70,PSEN1,STAT3,TUBGCP2,MRPL3,LUC7L2,SRSF1 |
| 3.821e-03 | -5.57 | NUP88 (nucleoporin 88) | protein interactions | 4927 | 41 | 14 | 17029 | 2761 |
RBM42,SUZ12,RAE1,NUP107,CIRBP,CUL3,NUP62,NUP153,CNTROB,PLEC,NUP85,IFI16,SEH1L,CAND1 |
| 3.821e-03 | -5.57 | Psmb4 (proteasome (prosome, macropain) subunit, beta type 4) | protein interactions | 19172 | 41 | 14 | 17029 | 2761 |
FAM192A,PSMD1,DNAJC8,PSMA6,HPS5,PSMD3,FBXO7,TMEM109,PSMB7,PSMA1,SMARCA4,PSMG1,PSMC1,PSMB3 |
| 3.821e-03 | -5.57 | Spast (spastin) | protein interactions | 50850 | 41 | 14 | 17029 | 2761 |
CHMP2A,PDCD6IP,PDCD6,ERLIN1,CAPN7,CENPF,FLOT1,ATP6V0A1,SARAF,CHMP4B,ATP6V1B2,CHMP2B,ATP6V0D1,ATP6V1G1 |
| 3.821e-03 | -5.57 | PURA (purine rich element binding protein A) | protein interactions | 5813 | 41 | 14 | 17029 | 2761 |
CDK5,RB1,RFC3,RAF1,E2F1,CUL3,CUL1,YBX1,TARDBP,RRS1,RFC2,ZC3H3,DDX23,CAND1 |
| 3.821e-03 | -5.57 | SPIN1 (spindlin 1) | protein interactions | 10927 | 41 | 14 | 17029 | 2761 |
SPINDOC,CYLD,EIF4A3,TCF3,TOPORS,BCLAF1,THRAP3,MCM2,VDAC1,ARRB2,SMURF1,CGGBP1,SSRP1,SUPT16H |
| 3.834e-03 | -5.56 | telomere organization | biological process | GO:0032200 | 121 | 30 | 17256 | 2622 |
POLA2,ERCC1,TELO2,RFC3,PRIM2,PRKDC,SMC6,DCLRE1C,BLM,RFC2,GAR1,PRIM1,DOT1L,XRCC5,RPA1,TERF2IP,RPA2,RAD51C,PCNA,UPF1,SP100,POLE,NSMCE2,XRCC3,PTGES3,H3F3A,POT1,TERF1,RAD51D,TERF2 |
| 3.837e-03 | -5.56 | Rhoa (ras homolog family member A) | protein interactions | 11848 | 25 | 10 | 17029 | 2761 |
MKNK1,FAM208B,CORO7,RHOA,POLK,SCYL1,COX5A,TXNL4A,ZNF518A,SMURF1 |
| 3.837e-03 | -5.56 | Timeless (timeless circadian clock 1) | protein interactions | 21853 | 25 | 10 | 17029 | 2761 |
RPA2,TRAPPC13,MCM10,CLSPN,TIMELESS,TAP2,MCM2,CHMP2B,GINS4,SPTAN1 |
| 3.837e-03 | -5.56 | CHCHD4 (coiled-coil-helix-coiled-coil-helix domain containing 4) | protein interactions | 131474 | 25 | 10 | 17029 | 2761 |
CHCHD1,TOR1AIP1,ILF3,HADHB,ABHD11,NDUFS5,ATP5F1B,RAB5B,RHOT2,RHBDD2 |
| 3.837e-03 | -5.56 | SEPT5 (septin 5) | protein interactions | 5413 | 25 | 10 | 17029 | 2761 |
SEPT1,KAT7,MAPK6,MRPL12,SEPT11,LSM8,SEPT8,SEPT7,APP,PLEKHF2 |
| 3.837e-03 | -5.56 | BMS1 (BMS1, ribosome biogenesis factor) | protein interactions | 9790 | 25 | 10 | 17029 | 2761 |
NIFK,CYLD,MEX3C,FOXM1,RPS14,USP42,CSNK2A1,RRS1,IFI16,RPSA |
| 3.837e-03 | -5.56 | ZNF669 (zinc finger protein 669) | protein interactions | 79862 | 25 | 10 | 17029 | 2761 |
TRIM41,ANKRD27,LTBP4,MTMR4,NEK7,SESTD1,KBTBD7,GGPS1,TRIM28,USP34 |
| 3.837e-03 | -5.56 | PURB (purine rich element binding protein B) | protein interactions | 5814 | 25 | 10 | 17029 | 2761 |
RPA2,RPS2,RFC3,CUL3,CSNK2A1,TARDBP,RRS1,PURA,RPSA,RPA1 |
| 3.837e-03 | -5.56 | RFFL (ring finger and FYVE like domain containing E3 ubiquitin protein ligase) | protein interactions | 117584 | 25 | 10 | 17029 | 2761 |
UBE2D3,USP7,MDM2,ATXN3,SHC1,UCHL5,RFFL,ESPL1,STAM,USP5 |
| 3.837e-03 | -5.56 | RNF170 (ring finger protein 170) | protein interactions | 81790 | 25 | 10 | 17029 | 2761 |
PON2,PSMA6,TM9SF4,ERLIN1,TYW1,MYH9,CHMP4B,ABCB10,PDE3B,ASPHD2 |
| 3.837e-03 | -5.56 | CSN1S1 (casein alpha s1) | protein interactions | 1446 | 25 | 10 | 17029 | 2761 |
PLK1,CDKN2AIP,ETV3,ERF,KLHL15,CSNK2A1,CUL1,TOLLIP,PARK7,HTRA2 |
| 3.837e-03 | -5.56 | WDFY2 (WD repeat and FYVE domain containing 2) | protein interactions | 115825 | 25 | 10 | 17029 | 2761 |
RBM17,DAP3,DSN1,CHERP,U2SURP,NUP54,RUFY1,C2CD5,NUP58,MIEF1 |
| 3.837e-03 | -5.56 | RNU11 (RNA, U11 small nuclear) | protein interactions | 26824 | 25 | 10 | 17029 | 2761 |
SNRNP25,SNRNP200,SF3B1,EFTUD2,YBX1,SNRPG,PDCD7,SNRPD3,DHX15,SF3B2 |
| 3.837e-03 | -5.56 | BOLA1 (bolA family member 1) | protein interactions | 51027 | 25 | 10 | 17029 | 2761 |
BOLA3,SLC25A51,ABHD11,BOLA1,GLRX3,PCBP1,COMMD8,APP,BIRC2,ECH1 |
| 3.837e-03 | -5.56 | MAST3 (microtubule associated serine/threonine kinase 3) | protein interactions | 23031 | 109 | 29 | 17029 | 2761 |
PRKAB1,NF1,FAM53C,DENND4C,PRKAA1,CSNK2A1,ATP5F1B,EIF2A,PCBP1,USP21,TRIM28,GIGYF1,LMNA,XRCC5,RTKN,RPL37,ZBTB21,EIF2S2,PTEN,FAM110A,HDAC7,KIF13B,PPP6C,DDX5,CDC25B,LRRC59,APOL2,ZC3HAV1,HNRNPM |
| 3.838e-03 | -5.56 | GO_INTRINSIC_COMPONENT_OF_ORGANELLE_MEMBRANE | MSigDB lists | GO_INTRINSIC_COMPONENT_OF_ORGANELLE_MEMBRANE | 245 | 53 | 17377 | 2626 |
IMMT,TOMM20,SYS1,HLA-E,TAP1,SLC39A13,PCSK7,ABCB10,SLC35B1,SLC35B2,QSOX2,BCAP31,RHBDD1,HLA-A,SPPL2A,TIMM23,RRBP1,SLC35B4,ARL6IP1,PIGG,ABCD1,TAP2,APOOL,TECR,ST8SIA2,VOPP1,BAK1,ANKLE2,PIGT,MFNG,SYVN1,ESYT1,TOMM40,RHOT1,RHOT2,CHCHD6,SPPL2B,MFN2,CHCHD3,LEMD2,DERL1,HLA-B,GALNT2,SEC61A1,GOLGA7,TIMM17A,PKD2,ST3GAL2,ATF6,SAMD8,CLN3,ESYT2,TMEM33 |
| 3.845e-03 | -5.56 | DARWICHE_SQUAMOUS_CELL_CARCINOMA_UP | MSigDB lists | DARWICHE_SQUAMOUS_CELL_CARCINOMA_UP | 132 | 32 | 17377 | 2626 |
SRM,GALK1,COX5B,GCLM,TXN,H2AFZ,DYNLL1,UCK2,KLF13,EXT2,CHKA,CAPN2,PDS5B,SUCLG2,RNF19A,CITED2,EEF1D,FTL,VHL,LDHA,LY6E,STX16,RAB2B,SRSF1,MAN2A2,IDE,LTBP4,ARAP1,UBE2C,PGAM1,CHPT1,HEXA |
| 3.855e-03 | -5.56 | Innate Immune System | REACTOME pathways | R-HSA-168249 | 1285 | 246 | 10287 | 1696 |
ADA2,RAB14,TXN,TSC2,ADAM10,NF1,PRKCSH,HEXB,CUL1,NHLRC3,GYG1,MAPK14,KCMF1,CMTM6,POLR3K,BIRC2,CALM2,PA2G4,RAP1A,PSMD1,CDC42,PIK3R2,AP1M1,DNM2,PCBP2,KCNAB2,MLST8,NRAS,NCK1,RBX1,AKT2,ARHGAP45,CYSTM1,UBE2V1,RAB5B,WAS,AGPAT2,RPS27A,PSMD8,LIMK1,CRCP,CAB39,ATP6V0C,ACTB,CLU,ROCK1,ARRB2,PSMC1,ATP6V0E1,CAPN1,SVIP,DDX58,UBE2D3,DNAJC5,GMFG,POLR2K,HLA-E,VAV2,DHX9,LAMTOR3,ASAH1,B4GALT1,MEF2A,CDK13,MAN2B1,PPP3CB,RAB6A,NCKAP1,PSEN1,PSMD9,TMEM179B,GNS,CD59,NFATC3,ARPC5,CAPZA1,ATP6V0A2,BCL2,OSTF1,RNF135,MVP,LPCAT1,ATP6V0D1,CYFIP1,FTL,CREG1,MAPKAPK3,PIP4K2C,PSMA1,C1orf35,KRAS,CAPZA2,PKM,CYFIP2,ICAM2,ELK1,ARPC1A,ARMC8,MAP2K2,CCT8,PSMB3,ISG15,PSMC4,XRCC5,CAND1,CAT,CSK,DUSP3,SNAP23,ACLY,PPP3R1,NLRC5,CTSA,GPI,RHOG,WASF2,CYLD,RAF1,DYNLL1,RPS6KA1,ACTR3,RAC1,MYH9,NIT2,IRF3,BCL2L1,ATP6V1B2,PRKACA,LYN,CPNE3,APP,VAV1,ATP6V0B,MDM2,PSMA6,SHC1,PIN1,ADCY9,BRI3,CDKN1B,MAVS,AHCYL1,ATF2,ABI1,TMBIM1,GM2A,CFL1,ATP6V1G1,ADCY7,ENPP4,CPNE1,CCT2,TIMP2,BIRC3,POLR2L,CGAS,PSMA8,RAB7A,PPIE,CUL3,PSMB7,ATP6V0A1,WIPF1,NFATC2,TOLLIP,PSMB9,PPP2CA,ALDH3B1,PPP2R5A,DDOST,DSN1,SURF4,JAK1,RAB24,TAB2,STAT6,PSMD3,CANT1,TICAM1,TRIM32,PDXK,PPP5C,LTA4H,MAPK1,TUBB,MIF,OTUD5,MANBA,PDAP1,AGO2,BRAP,SIKE1,AKT1S1,MYO9B,FOXO3,PIP4K2A,HLA-A,PLPP5,PIP5K1C,FGFR3,PSMD2,CTSS,GRK2,PTEN,HUWE1,TANK,PTPN11,CNN2,CREB1,MAP3K14,CNPY3,UBE2M,MYO5A,CAMK2G,SPTAN1,PDPK1,PPP3CA,RHOA,MLEC,TNFAIP3,PRKDC,PRKAR1B,HEBP2,POLR3GL,FADD,NEU1,HSPA1B,MAPK3,CTSL,HLA-B,RAB18,PLD3,ATP6V1D,GOLGA7,MAGT1,ELMO1,SNAP29,KBTBD7,DTX4,PGRMC1,IMPDH1,PSAP,ATP6V1C1,PGAM1,HRAS,IFI16 |
| 3.855e-03 | -5.56 | GSE22935_WT_VS_MYD88_KO_MACROPHAGE_24H_MBOVIS_BCG_STIM_DN | MSigDB lists | GSE22935_WT_VS_MYD88_KO_MACROPHAGE_24H_MBOVIS_BCG_STIM_DN | 185 | 42 | 17377 | 2626 |
SEPHS2,TCF12,RRP15,ABCC10,KLC1,NUF2,SLC29A1,THRAP3,OAT,MRPL19,MAN1A1,SSR1,FERMT3,SLC31A1,RNF121,ERH,MECR,ZBTB22,NFU1,LPCAT1,SPSB3,HP1BP3,EBAG9,ADAM17,DDX24,DCAF8,METTL5,LACTB,SMAP2,GNA12,MKNK1,SYNCRIP,MAP4,SRSF3,ROCK1,RUVBL2,FAU,PDLIM5,RPS6KC1,SNX14,COIL,SLC25A33 |
| 3.855e-03 | -5.56 | GSE17721_CPG_VS_GARDIQUIMOD_16H_BMDC_DN | MSigDB lists | GSE17721_CPG_VS_GARDIQUIMOD_16H_BMDC_DN | 185 | 42 | 17377 | 2626 |
NAT9,TRIM41,PDCD6IP,HNRNPAB,NQO1,ARID5A,PLAGL2,CDIPT,HMG20A,CCDC28A,XPR1,TMEM179B,SLC31A1,INTS7,CAPZA1,DAPK1,TECR,CITED2,ABI1,RNF5,FDFT1,GINS1,ERMP1,USO1,BAZ2A,HNRNPF,RPL38,ARHGDIB,ADRB2,UBE4B,SOX4,TANC1,TRIM28,DDX17,ANKZF1,ATP1A1,PARG,PRMT7,YWHAZ,ST3GAL2,ATP6V1C1,SNRNP70 |
| 3.855e-03 | -5.56 | GSE7831_1H_VS_4H_CPG_STIM_PDC_DN | MSigDB lists | GSE7831_1H_VS_4H_CPG_STIM_PDC_DN | 185 | 42 | 17377 | 2626 |
FOXM1,IVNS1ABP,DYNLL1,PDAP1,TRIO,KIF23,CTCF,CDK13,UBE4A,NANS,IL21R,STMN1,LIN9,CTSS,NEK6,RCSD1,ZNF326,CDC25B,MGAT5,GM2A,IMPA2,NTPCR,PRKDC,EMB,SELPLG,MAP7D1,NUTF2,PKMYT1,API5,MASTL,CXXC4,KIF18A,TMED10,LSM6,SNAP29,H2AFX,COX5A,BAZ1B,AKNA,SLC25A39,LRP8,FAM72A |
| 3.855e-03 | -5.56 | GSE2197_IMMUNOSUPPRESSIVE_DNA_VS_UNTREATEDIN_DC_DN | MSigDB lists | GSE2197_IMMUNOSUPPRESSIVE_DNA_VS_UNTREATEDIN_DC_DN | 185 | 42 | 17377 | 2626 |
GGNBP2,CAST,MOGS,KLC1,NKRF,AKT1S1,NANS,MCTS1,MOAP1,CAPN2,SEC11A,STARD9,GART,CCNA2,CTNNBL1,MED8,RINL,KIF22,MAVS,PHKG2,ILKAP,NAGPA,NTPCR,TIMP2,KLF10,EID1,SIGMAR1,ASPM,METTL5,TEX10,BORA,MTR,TTC33,AKAP1,SH3BP5,PAF1,TRIM47,SGSH,ZNF330,MEGF9,SSNA1,GCSH |
| 3.855e-03 | -5.56 | GSE24210_RESTING_TREG_VS_TCONV_UP | MSigDB lists | GSE24210_RESTING_TREG_VS_TCONV_UP | 185 | 42 | 17377 | 2626 |
SYS1,MANBA,ARID5A,CDCA3,ACAP1,MED13L,KLF13,CDC42SE2,NOTCH2,NCAPG,RUFY1,LYN,GNB2,UBLCP1,NAPG,SSBP3,SRI,CABLES2,N4BP2,PHF20L1,CYTH1,PTPN18,KIAA0040,ERLIN1,PPP1R21,OXR1,MTMR6,MEF2D,AZI2,SHCBP1,RFC2,BSDC1,SMAP2,DHX57,RPA1,HHEX,JAK1,ROCK1,MAP3K5,TMEM14A,PDCD4,HIGD2A |
| 3.855e-03 | -5.56 | GSE369_SOCS3_KO_VS_WT_LIVER_DN | MSigDB lists | GSE369_SOCS3_KO_VS_WT_LIVER_DN | 185 | 42 | 17377 | 2626 |
CMAS,CYLD,PNISR,MECP2,DLGAP4,MEF2A,ELMOD2,BIRC2,HMG20A,PAIP2,C2orf68,ARPC5,ZNF260,PIK3IP1,FAM76B,RNF19A,ABI1,NCOA2,HP1BP3,CYTH1,TSPYL4,DENND1B,PPP1R21,LACTB,COG1,CKAP2L,RTF1,ARHGDIB,WBP1,CBFB,SERP1,ARHGAP15,KRIT1,DCK,CNOT6,MBD6,CCDC125,NDE1,RBBP4,BRD9,HIPK3,DCAF5 |
| 3.855e-03 | -5.56 | GSE360_DC_VS_MAC_DN | MSigDB lists | GSE360_DC_VS_MAC_DN | 185 | 42 | 17377 | 2626 |
KIF3B,PLXNC1,ANXA6,TSC22D3,DYNLL1,NACA,CDK2AP2,BTN3A1,FOXO3,RALB,RRBP1,SEPT11,TNPO3,ECD,MRPL40,SLC25A1,TGFB1,PLK3,TIMP2,ERF,NSDHL,LDHA,RPS24,EMP3,AURKB,MEF2D,CADM1,OGFR,PRDX1,MYO1F,SCARB2,TPD52L2,CDC16,PPP1R11,ATP6V0C,SSNA1,USF2,IGBP1,RPS26,POT1,IFI16,DDX52 |
| 3.860e-03 | -5.56 | HALLMARK_UV_RESPONSE_UP | MSigDB lists | HALLMARK_UV_RESPONSE_UP | 153 | 36 | 17377 | 2626 |
PPP1R2,PDAP1,UROD,TAP1,DNAJB1,SPR,PRKACA,LYN,TFRC,CHKA,RPN1,IL6ST,CYB5R1,CLTB,EIF5,CDC5L,BAK1,PPIF,PPT1,CREG1,SIGMAR1,BTG2,AMD1,DNAJA1,PRPF3,POLG2,MARK2,TARS,RHOB,RXRB,CEBPG,H2AFX,ATP6V1C1,ARRB2,CDK2,AP2S1 |
| 3.861e-03 | -5.56 | spindle_and_epithelioid | COSMIC cancer mutations | spindle_and_epithelioid | 19 | 8 | 17385 | 2587 |
RB1,NRAS,NF1,PTEN,KRAS,MAP2K2,HRAS,CDKN2A |
| 3.861e-03 | -5.56 | haematopoietic_and_lymphoid_tissue-lymph_node-lymphoid_neoplasm-chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-lymph_node-lymphoid_neoplasm-chronic_lymphocytic_leukaemia-small_lymphocytic_lymphoma | 19 | 8 | 17385 | 2587 |
RB1,KRAS,NRAS,BIRC3,PTEN,SF3B1,HRAS,CDKN2A |
| 3.861e-03 | -5.56 | gliosarcoma | COSMIC cancer mutations | gliosarcoma | 19 | 8 | 17385 | 2587 |
CDKN2C,KRAS,NRAS,H3F3A,PTEN,SF3B1,HRAS,CDKN2A |
| 3.861e-03 | -5.56 | soft_tissue-fibrous_tissue_and_uncertain_origin-gastrointestinal_stromal_tumour-spindle_and_epithelioid | COSMIC cancer mutations | soft_tissue-fibrous_tissue_and_uncertain_origin-gastrointestinal_stromal_tumour-spindle_and_epithelioid | 19 | 8 | 17385 | 2587 |
RB1,NRAS,NF1,PTEN,KRAS,HRAS,MAP2K2,CDKN2A |
| 3.864e-03 | -5.56 | HTT (huntingtin) | protein interactions | 3064 | 178 | 43 | 17029 | 2761 |
MBD1,GOLPH3L,CASP6,TRIP10,DNAJB2,AGO2,TKT,KIF23,DNAJB1,UBQLN2,GGA2,HMG20A,MBD4,PDK2,SIAH1,HUWE1,OSTF1,CREB1,MORC3,SAP30,FTL,TRAFD1,TACC1,PSMB7,RFXANK,SYVN1,DNAJA1,PRMT2,SYMPK,SH3GLB1,RHEB,ECH1,MAPK3,OPTN,PPP2CA,HLA-B,HSPA4,CHD3,AXIN1,PML,MRFAP1L1,NUP58,TUBB |
| 3.869e-03 | -5.55 | cellular response to exogenous dsRNA | biological process | GO:0071360 | 15 | 7 | 17256 | 2622 |
DDX58,MAVS,CGAS,RALB,DHX9,FLOT1,PQBP1 |
| 3.869e-03 | -5.55 | deoxyribonucleotide biosynthetic process | biological process | GO:0009263 | 15 | 7 | 17256 | 2622 |
RRM2,DCTD,GUK1,DUT,HDDC2,RRM1,TBPL1 |
| 3.869e-03 | -5.55 | regulation of mitophagy | biological process | GO:1901524 | 15 | 7 | 17256 | 2622 |
TSC2,TIGAR,SMURF1,HTRA2,OPTN,MFN2,CDC37 |
| 3.869e-03 | -5.55 | regulation of Rac protein signal transduction | biological process | GO:0035020 | 15 | 7 | 17256 | 2622 |
KRAS,ARHGAP17,SH3BP1,NF1,ALS2,OGT,DNM2 |
| 3.869e-03 | -5.55 | blastocyst growth | biological process | GO:0001832 | 15 | 7 | 17256 | 2622 |
GINS1,CTR9,RTF1,PALB2,ZNF830,GINS4,PRPF19 |
| 3.869e-03 | -5.55 | septin ring assembly | biological process | GO:0000921 | 15 | 7 | 17256 | 2622 |
SEPT11,TMEM250,SEPT8,SEPT1,SEPT9,SEPT7,ANLN |
| 3.875e-03 | -5.55 | PID_ERBB1_RECEPTOR_PROXIMAL_PATHWAY | MSigDB lists | PID_ERBB1_RECEPTOR_PROXIMAL_PATHWAY | 35 | 12 | 17377 | 2626 |
NRAS,SHC1,NCK1,PIK3R2,STAT1,PTPN11,KRAS,STAT3,MAPK1,HRAS,MAPK3,PIP5K1C |
| 3.875e-03 | -5.55 | REACTOME_ACTIVATION_OF_ATR_IN_RESPONSE_TO_REPLICATION_STRESS | MSigDB lists | REACTOME_ACTIVATION_OF_ATR_IN_RESPONSE_TO_REPLICATION_STRESS | 35 | 12 | 17377 | 2626 |
RPA2,RFC3,MCM10,MCM5,DBF4,CDC6,ORC1,MCM2,ORC3,RFC2,CDK2,RPA1 |
| 3.889e-03 | -5.55 | Kit receptor signaling pathway | WikiPathways | WP304 | 60 | 18 | 5312 | 837 |
RAF1,RPS6KA1,MAPK14,LYN,FOXO3,MAP2K2,MAPK3,VAV1,CRKL,SHC1,PIK3R2,SOCS6,STAT1,PTPN11,BCL2,MAPK1,STAT3,HRAS |
| 3.889e-03 | -5.55 | GSE46606_IRF4_KO_VS_WT_CD40L_IL2_IL5_3DAY_STIMULATED_BCELL_DN | MSigDB lists | GSE46606_IRF4_KO_VS_WT_CD40L_IL2_IL5_3DAY_STIMULATED_BCELL_DN | 169 | 39 | 17377 | 2626 |
CHMP2A,PIGM,C1orf112,SLC35B1,CRLF3,LYN,ZNF79,PITHD1,VPS25,ATPAF1,CAPN2,INPP5A,SEC24C,GMEB1,NSFL1C,ATP6V0D1,ELOF1,PAQR6,NOL12,TACC1,RNF25,TMEM216,RFC2,DDX39A,HMGN2,TPD52L2,GNA12,KPNA1,UPF1,SURF4,HNRNPH3,SAFB,CAB39,NCOA1,WDR91,ZNF830,BRWD3,CHMP7,CCDC59 |
| 3.889e-03 | -5.55 | GSE12366_PLASMA_CELL_VS_MEMORY_BCELL_UP | MSigDB lists | GSE12366_PLASMA_CELL_VS_MEMORY_BCELL_UP | 169 | 39 | 17377 | 2626 |
CCNC,TMEM184B,SEC61G,CDK2AP2,SLC35B1,RGS2,FAM8A1,COPB2,SSR1,MAN1A1,ATP2A2,NDUFB4,UBA5,PPCDC,TECR,OSTC,PREB,TMEM39A,BTG2,OAF,PRKAR1B,GORASP2,PRKRA,ICAM2,CXXC4,DERL1,TSC1,IDE,GALNT2,UAP1,CCDC14,TPP2,GLG1,USP32,SIL1,SPCS3,CHPF2,CBX4,ZSWIM6 |
| 3.889e-03 | -5.55 | BROWNE_HCMV_INFECTION_18HR_UP | MSigDB lists | BROWNE_HCMV_INFECTION_18HR_UP | 169 | 39 | 17377 | 2626 |
FGFR1OP,SNX27,PPP1R2,CASP6,NF1,TAP1,LYN,CREM,FANCL,ZNF473,SLC1A4,SAR1A,SS18L1,TP53BP2,SPTSSA,ATF2,MORC3,ABCC5,CDC5L,ENPP4,MKLN1,ERF,AMD1,E2F3,FXR1,RXRB,MAN2A2,UTP20,UPF1,MTHFD2,SEC23IP,CDC27,PPM1G,CAPN7,PPP3R1,RBBP4,CDK2,TERF1,COIL |
| 3.938e-03 | -5.54 | regulation of membrane permeability | biological process | GO:0090559 | 86 | 23 | 17256 | 2622 |
BAK1,PPIF,ATP5IF1,PDCD6IP,DYNLL1,HEBP2,BCL2L1,RHOT1,SLC25A5,RHOT2,MOAP1,TFDP1,E2F1,PPP3R1,BCL2,YWHAZ,TP53BP2,TFDP2,TMEM14A,ATF2,YWHAH,STAT3,EYA2 |
| 3.944e-03 | -5.54 | MARTINEZ_RESPONSE_TO_TRABECTEDIN_UP | MSigDB lists | MARTINEZ_RESPONSE_TO_TRABECTEDIN_UP | 67 | 19 | 17377 | 2626 |
GUK1,GLO1,CYCS,WBP1,VKORC1,GNAS,FKBP1A,NDUFA2,GADD45B,COX8A,ADAM9,ANXA5,CTSA,YBX1,TNRC18,MYL12B,RHBDD2,ATP6V1G1,CDC37 |
| 3.944e-03 | -5.54 | PID_P75_NTR_PATHWAY | MSigDB lists | PID_P75_NTR_PATHWAY | 67 | 19 | 17377 | 2626 |
ADAM17,MAGEH1,RHOA,BIRC3,CASP6,APH1A,RHOC,MAGED1,RAC1,XIAP,CYCS,PSEN1,APH1B,APP,BIRC2,RHOB,SHC1,PRDM4,E2F1 |
| 3.944e-03 | -5.54 | KEGG_EPITHELIAL_CELL_SIGNALING_IN_HELICOBACTER_PYLORI_INFECTION | MSigDB lists | KEGG_EPITHELIAL_CELL_SIGNALING_IN_HELICOBACTER_PYLORI_INFECTION | 67 | 19 | 17377 | 2626 |
ADAM17,ADAM10,RAC1,ATP6V0A1,ATP6V1B2,MAPK14,LYN,ATP6V0B,ATP6V1D,CDC42,CSK,PTPN11,ATP6V0A2,ATP6V0C,ATP6V1C1,MAP3K14,ATP6V0D1,ATP6V0E1,ATP6V1G1 |
| 3.944e-03 | -5.54 | PID_TELOMERASE_PATHWAY | MSigDB lists | PID_TELOMERASE_PATHWAY | 67 | 19 | 17377 | 2626 |
SP3,TGFB1,MAX,BLM,MXD1,MAPK3,XRCC5,TERF2IP,E2F1,CDKN1B,PTGES3,RBBP4,NR2F2,MAPK1,TERF1,POT1,HDAC2,SAP30,TERF2 |
| 3.947e-03 | -5.53 | ACTL6A (actin like 6A) | protein interactions | 86 | 114 | 30 | 17029 | 2761 |
CCT2,RAB14,EWSR1,USO1,H2AFZ,KAT2A,CUL3,SMARCA4,NFATC2,PBRM1,INO80E,ARID1A,HDGFL2,ARID1B,MAP2K2,POLR2A,CAND1,DDRGK1,HINT1,UCHL5,BANF1,BCL7C,ZRANB2,RUVBL2,YY1,SMARCE1,CDK2,RPRD1B,HDAC2,SMARCD1 |
| 3.959e-03 | -5.53 | FAM98A (family with sequence similarity 98 member A) | protein interactions | 25940 | 37 | 13 | 17029 | 2761 |
CMAS,CUL3,CUL1,RACGAP1,TARDBP,COPS7B,BRCA1,FUS,MCM2,N4BP2,BTBD1,LUC7L2,CAND1 |
| 3.959e-03 | -5.53 | DR1 (down-regulator of transcription 1) | protein interactions | 1810 | 37 | 13 | 17029 | 2761 |
METTL1,MBIP,KAT2A,GOPC,DRAP1,NFIL3,BTF3L4,CREB1,WDR5,TTLL12,LRSAM1,SGF29,NPLOC4 |
| 3.959e-03 | -5.53 | UBE2J1 (ubiquitin conjugating enzyme E2 J1) | protein interactions | 51465 | 37 | 13 | 17029 | 2761 |
DERL1,BIRC3,SEL1L,TMEM216,TOPORS,ASNA1,BRCA1,SYVN1,LRSAM1,BIRC2,RNF5,HLA-A,EVC2 |
| 3.959e-03 | -5.53 | MAP7 (microtubule associated protein 7) | protein interactions | 9053 | 37 | 13 | 17029 | 2761 |
RECQL,PPP4R1,KBTBD7,DHX9,SEC16A,POT1,CTDSP2,TERF1,APP,SSSCA1,DCTN1,CDC5L,SRPK2 |
| 3.959e-03 | -5.53 | MITF (melanogenesis associated transcription factor) | protein interactions | 4286 | 37 | 13 | 17029 | 2761 |
RB1,HINT1,KLHL20,TFE3,RPS6KA1,PIAS2,UBE2I,CDK2,MAPK1,MAPK14,APP,EBP,TFEB |
| 3.959e-03 | -5.53 | ATP5ME (ATP synthase membrane subunit e) | protein interactions | 521 | 37 | 13 | 17029 | 2761 |
SMAD2,TIMMDC1,CCDC14,KIF14,VDAC2,ATP5F1B,ATP5F1A,SPRYD4,CYC1,APOOL,TOMM40,VDAC1,ATP5PF |
| 3.959e-03 | -5.53 | MPP3 (membrane palmitoylated protein 3) | protein interactions | 4356 | 37 | 13 | 17029 | 2761 |
TRIM41,RPS2,NOA1,GNG7,EZR,RRAGC,MDH1,CADM1,ERBIN,MCM2,APP,SRPK2,CCDC137 |
| 3.959e-03 | -5.53 | Mta1 (metastasis associated 1) | protein interactions | 116870 | 37 | 13 | 17029 | 2761 |
PWWP2A,CSNK1G2,NCK1,CHD3,ZNF639,MTA2,MBD2,PHF14,BABAM1,RBBP4,MBD3,HMG20A,HDAC2 |
| 3.959e-03 | -5.53 | ARRDC3 (arrestin domain containing 3) | protein interactions | 57561 | 37 | 13 | 17029 | 2761 |
FGFR3,UBE2E2,HGS,PDCD6IP,TNFAIP3,ADRB2,IKBIP,ARRB2,F2R,STAM,CD320,CSNK1G3,WWP2 |
| 3.976e-03 | -5.53 | ovary-germ_cell_tumour-teratoma | COSMIC cancer mutations | ovary-germ_cell_tumour-teratoma | 23 | 9 | 17385 | 2587 |
KRAS,DNMT3A,NRAS,PTEN,SF3B1,HRAS,SMAD4,CDKN2A,MSH2 |
| 3.981e-03 | -5.53 | ATP6V0E1 (ATPase H+ transporting V0 subunit e1) | protein interactions | 8992 | 11 | 6 | 17029 | 2761 |
ATP6V0A1,PTPRF,ATP6V0A2,ACP2,REEP5,PIGG |
| 3.981e-03 | -5.53 | SERINC3 (serine incorporator 3) | protein interactions | 10955 | 11 | 6 | 17029 | 2761 |
SLC16A1,RPS15,SURF4,PHB2,KDELR1,VDAC2 |
| 3.981e-03 | -5.53 | COQ10B (coenzyme Q10B) | protein interactions | 80219 | 11 | 6 | 17029 | 2761 |
CHCHD2,TIMM8B,CYCS,PITRM1,ECH1,STOML2 |
| 3.981e-03 | -5.53 | KCNA6 (potassium voltage-gated channel subfamily A member 6) | protein interactions | 3742 | 11 | 6 | 17029 | 2761 |
HERC3,GOLM1,SLC4A2,RHBDD1,KCNAB2,HADHB |
| 3.981e-03 | -5.53 | DDX43 (DEAD-box helicase 43) | protein interactions | 55510 | 11 | 6 | 17029 | 2761 |
KRAS,GORASP2,HNRNPH3,APP,DHX15,LMNA |
| 3.981e-03 | -5.53 | ZHX3 (zinc fingers and homeoboxes 3) | protein interactions | 23051 | 11 | 6 | 17029 | 2761 |
TFAP4,ATXN1,EWSR1,PDIA6,ZHX1,WDYHV1 |
| 3.981e-03 | -5.53 | Tnks1bp1 (tankyrase 1 binding protein 1) | protein interactions | 228140 | 11 | 6 | 17029 | 2761 |
CNOT9,CAPZA2,FOXM1,MTA1,CNOT3,CAPZA1 |
| 3.982e-03 | -5.53 | ARAF (A-Raf proto-oncogene, serine/threonine kinase) | protein interactions | 369 | 95 | 26 | 17029 | 2761 |
DPM1,AGTRAP,PBK,SLC25A22,KRAS,DNAJA1,DIDO1,ATP5F1B,RAB3IP,PKM,MAP2K2,TRIM28,RPL37,GNA12,MYO18A,PPP6C,YWHAZ,DDX5,FKBP5,TECR,YWHAH,LRRC59,HRAS,SLC25A1,TIMM50,CDC37 |
| 3.982e-03 | -5.53 | TMEM206 (transmembrane protein 206) | protein interactions | 55248 | 95 | 26 | 17029 | 2761 |
NOP9,NRAS,PBXIP1,C19orf25,TBRG4,NUP155,DCUN1D5,TMEM147,USP22,XPO7,GNB2,BZW2,TUBGCP2,DDRGK1,PI4K2A,ASPHD2,THADA,KIF14,TNPO3,TNPO2,CISD2,KNTC1,NR2F2,STAT3,MZT2B,TSPAN5 |
| 3.983e-03 | -5.53 | VARS (valyl-tRNA synthetase) | protein interactions | 7407 | 81 | 23 | 17029 | 2761 |
OTUD5,LARS,STAU1,TP53RK,CYLD,LAP3,CUL3,BRCA1,MCFD2,EPB41,PTPN2,DERL1,HLA-B,AHNAK,SHC1,TFE3,QARS,KNTC1,DMWD,CORO1A,CDK2,EEF1D,POC5 |
| 3.983e-03 | -5.53 | NSF (N-ethylmaleimide sensitive factor, vesicle fusing ATPase) | protein interactions | 4905 | 81 | 23 | 17029 | 2761 |
PRKAB1,STAU1,USO1,MRPL9,BABAM1,PMS2,CUL3,BRCA1,ADRB2,PCGF1,GOSR1,SEC31A,NAPG,NSF,RAB24,SNAP29,SNAP23,STAT1,RPLP1,ATP6V0D1,LUC7L2,CSNK1G3,CDC5L |
| 3.983e-03 | -5.53 | STK24 (serine/threonine kinase 24) | protein interactions | 8428 | 81 | 23 | 17029 | 2761 |
MOB4,CCT2,PDCD6IP,STRIP1,DYNLL1,VAV2,TRMT6,STRN4,SIKE1,CCT8,MAT2B,PPP2CA,PDCD10,SYNCRIP,HNRNPH3,LRPPRC,DDX5,STK11,EIF5,FGFR1OP2,TUBB,CDC5L,ZBTB24 |
| 3.983e-03 | -5.53 | STOML2 (stomatin like 2) | protein interactions | 30968 | 81 | 23 | 17029 | 2761 |
COX15,EWSR1,PTPN18,PHB2,COQ10B,SUZ12,RAB7A,NDUFA4,ADCK5,RAB1A,VDAC1,MYEF2,HAUS2,MATR3,APP,DAP3,SYNCRIP,PSMD3,ATP5F1A,MRPL40,APOOL,LMAN1,MRPL32 |
| 3.983e-03 | -5.53 | ZNF131 (zinc finger protein 131) | protein interactions | 7690 | 81 | 23 | 17029 | 2761 |
TK1,SEC61B,TRAFD1,KDM4A,NFATC2,PRPF3,RAB6A,SNRPD3,POLR2A,ZBTB45,PWWP2B,MBIP,AHNAK,TXLNA,UHRF2,KMT2B,KPNA2,CREB1,NSUN4,MTPN,MRM3,CBX4,MRM2 |
| 3.987e-03 | -5.52 | BLALOCK_ALZHEIMERS_DISEASE_INCIPIENT_UP | MSigDB lists | BLALOCK_ALZHEIMERS_DISEASE_INCIPIENT_UP | 375 | 76 | 17377 | 2626 |
ZBTB10,CAST,UROD,RBM8A,NENF,KTN1,APP,CPNE3,CSDE1,ATG3,RNASEH2A,FAM3A,F2R,OGG1,CTDSP2,ARID4A,SRPK2,CDC5L,ADCY7,SP3,ARHGAP17,ERF,TOPORS,MCL1,PBRM1,H2AFV,WAS,RBL1,LUC7L3,ZNF268,CLU,H3F3A,FAM208A,TSPAN5,ABCA1,CCDC59,PRPF4B,EWSR1,CASP6,TCF3,DBF4,BRAP,ITGB5,NCAPG,CFLAR,WWP2,FGFR3,TNS3,ADD3,CTSS,KLHL20,PPIG,POLR1B,TMEM8A,CNPY3,ZNF84,TACC1,NSDHL,TSPAN31,NEK7,ZMYM5,RPS10,SSR2,ARID1A,RXRB,PI4K2A,SLC19A1,NAP1L1,GOLGA4,OSBPL11,QARS,MFAP1,ZC3H7B,RBPJ,TCOF1,APOL2 |
| 3.988e-03 | -5.52 | PFKL (phosphofructokinase, liver type) | protein interactions | 5211 | 54 | 17 | 17029 | 2761 |
STAU1,PSMG1,BRCA1,PKM,PSMD9,APP,GTPBP3,ADSS,PSMD2,PRDX3,ZNF746,DMWD,FUS,COPS6,ZC3HC1,PFKP,TERF2 |
| 3.988e-03 | -5.52 | NCKIPSD (NCK interacting protein with SH3 domain) | protein interactions | 51517 | 54 | 17 | 17029 | 2761 |
FGFR1OP,NCK1,SMC6,CAPZA2,CNTROB,CSNK1A1,ARMC8,PSMD9,GIT2,MAPK3,WAS,FBXO28,ITGB1,GEMIN6,RBM15,PDCD2L,RBM15B |
| 3.988e-03 | -5.52 | ERH (ERH, mRNA splicing and mitosis factor) | protein interactions | 2079 | 54 | 17 | 17029 | 2761 |
CTDP1,COX15,FAM208B,CYLD,SUZ12,CSNK2A1,KRAS,VDAC1,EIF1B,APP,DGCR8,EIF4A3,COPS6,CHTOP,ARRB2,CDK2,TERF2 |
| 3.988e-03 | -5.52 | TIMMDC1 (translocase of inner mitochondrial membrane domain containing 1) | protein interactions | 51300 | 54 | 17 | 17029 | 2761 |
COX5B,NDUFB6,UQCR10,TMEM126B,NDUFA4,ARL5B,APP,NDUFS7,NDUFV1,HGS,NDUFB4,COX7A2L,LRPPRC,NDUFB9,NDUFS8,NDUFS5,NDUFA3 |
| 3.988e-03 | -5.52 | NASP (nuclear autoantigenic sperm protein) | protein interactions | 4678 | 54 | 17 | 17029 | 2761 |
PPP3CA,POLR2G,GSPT2,PRKACA,ASF1B,TERF2IP,MAT2B,HUWE1,KLF16,TIMELESS,H3F3A,ATP6V1C1,RBBP4,CDK2,LUC7L2,KCNAB2,TERF2 |
| 3.988e-03 | -5.52 | SRP9 (signal recognition particle 9) | protein interactions | 6726 | 54 | 17 | 17029 | 2761 |
SRP72,LARS,TXN,RPRD1A,DHPS,TRMT6,DDX20,TOMM40,EEF2K,GEMIN5,MTHFD2,RAD18,EXOSC1,PTGES3,GEMIN4,SZRD1,DCTN1 |
| 4.004e-03 | -5.52 | Snrnp70 (small nuclear ribonucleoprotein 70 (U1)) | protein interactions | 20637 | 29 | 11 | 17029 | 2761 |
GEMIN5,TXN,SNRPB,DDX20,GEMIN6,GEMIN4,SNRPG,SNRPD3,STRAP,CAPN1,GEMIN7 |
| 4.004e-03 | -5.52 | LDHAL6A (lactate dehydrogenase A like 6A) | protein interactions | 160287 | 29 | 11 | 17029 | 2761 |
WDR1,ARF5,MDH2,SUCLG2,MDH1,ARF1,PKM,TALDO1,SDHA,ARF4,CFL1 |
| 4.004e-03 | -5.52 | B3GNT2 (UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2) | protein interactions | 10678 | 29 | 11 | 17029 | 2761 |
CAPN2,PON2,ITGB8,ADAM10,TOR3A,FAM3C,TOR1AIP2,GALNT7,EDEM2,FAM3A,ATP6V0D1 |
| 4.004e-03 | -5.52 | CHRAC1 (chromatin accessibility complex 1) | protein interactions | 54108 | 29 | 11 | 17029 | 2761 |
ADSS,TFAP4,CHMP4A,DCK,UROD,CUTA,PTPN11,CRCP,TALDO1,APP,XRCC5 |
| 4.004e-03 | -5.52 | SURF6 (surfeit 6) | protein interactions | 6838 | 29 | 11 | 17029 | 2761 |
NOL12,COX15,DGCR8,RPL6,CSNK2A1,EBNA1BP2,RRS1,VDAC1,MAK16,ZC3H3,GPATCH4 |
| 4.004e-03 | -5.52 | COMMD6 (COMM domain containing 6) | protein interactions | 170622 | 29 | 11 | 17029 | 2761 |
CCDC93,COMMD10,UNK,VPS26C,EMB,TFDP1,COMMD5,COMMD4,COMMD6,COMMD8,VPS29 |
| 4.004e-03 | -5.52 | HIST1H2BC (histone cluster 1 H2B family member c) | protein interactions | 8347 | 29 | 11 | 17029 | 2761 |
COX15,DDX56,EIF4A3,MCM5,VHL,H2AFX,MEF2A,TP53BP2,MCM2,VDAC1,SDHA |
| 4.004e-03 | -5.52 | NOMO1 (NODAL modulator 1) | protein interactions | 23420 | 29 | 11 | 17029 | 2761 |
RPN1,UBQLN4,EWSR1,STAT1,ILF3,AGPAT3,UPF2,NCLN,PLEC,METTL9,CDK2 |
| 4.004e-03 | -5.52 | CSTF2T (cleavage stimulation factor subunit 2 tau variant) | protein interactions | 23283 | 29 | 11 | 17029 | 2761 |
UBQLN4,HGS,EWSR1,GOLGA2,U2SURP,CPSF4,SYMPK,BIRC2,MAPK3,CSTF1,PAPOLA |
| 4.004e-03 | -5.52 | GAS2L1 (growth arrest specific 2 like 1) | protein interactions | 10634 | 29 | 11 | 17029 | 2761 |
CDKN2C,USP7,MAPRE1,E2F4,E2F1,EPN1,KLHL42,CAPZA2,CCNB1,WDR45B,POT1 |
| 4.004e-03 | -5.52 | TXNL4A (thioredoxin like 4A) | protein interactions | 10907 | 29 | 11 | 17029 | 2761 |
UNK,SYNCRIP,PQBP1,HNRNPF,USP39,PRPF4,KRAS,PRPF3,SNRPG,RHEBL1,DDX23 |
| 4.006e-03 | -5.52 | N-methyltransferase activity | molecular function | GO:0008170 | 95 | 25 | 17224 | 2647 |
ASH1L,HEMK1,KMT2E,CXXC1,SUZ12,EHMT1,WDR82,NSD3,EZH1,WDR5,MEN1,METTL22,KMT2C,PRMT2,DOT1L,IRF4,KMT5C,SUV39H2,KMT5A,SETD3,CAMKMT,KMT2B,PRMT7,FBL,CARM1 |
| 4.007e-03 | -5.52 | - | gene3d domains | 3.30.379.10 | 3 | 3 | 8148 | 1295 |
HEXA,NAGLU,HEXB |
| 4.009e-03 | -5.52 | GSE9037_CTRL_VS_LPS_4H_STIM_BMDM_DN | MSigDB lists | GSE9037_CTRL_VS_LPS_4H_STIM_BMDM_DN | 180 | 41 | 17377 | 2626 |
TMBIM4,PPP1R15B,STARD7,VTI1A,UBE2Z,SLC20A1,MYEF2,SCYL2,REPS1,MXD1,TMCC3,NDUFS4,FBRS,MRPL50,SUB1,PDCD10,LRRC8D,PPIG,IL6ST,MECR,TAP2,CABLES2,RNF135,PTPRK,SRSF10,STAU1,USO1,C16orf72,UTP15,AZI2,FXR1,ODC1,TWISTNB,BRD2,CERS6,ARNTL,STAT1,MYO9A,ARHGAP23,NGLY1,ZC3HC1 |
| 4.009e-03 | -5.52 | GSE9960_HEALTHY_VS_GRAM_NEG_SEPSIS_PBMC_DN | MSigDB lists | GSE9960_HEALTHY_VS_GRAM_NEG_SEPSIS_PBMC_DN | 180 | 41 | 17377 | 2626 |
CYTIP,CDS2,LYRM4,UGP2,TRIP10,UBE2Z,CSNK2A1,SLC20A1,PPP1R16B,CMTM6,RGS1,MAD2L2,CFLAR,RAD23A,FBRS,CLIC4,TNFAIP8,ZNRF2,NSRP1,MCM5,TANK,SLC44A1,AKR1B1,CLDND1,TAGLN2,ACSL5,TXNL1,IFRD1,ETV3,MKLN1,ELL2,LAP3,LYRM1,PSMA1,RFFL,PLEKHM3,TARS,ACLY,TICAM1,NDE1,LRP8 |
| 4.009e-03 | -5.52 | GSE22886_NAIVE_CD8_TCELL_VS_NKCELL_UP | MSigDB lists | GSE22886_NAIVE_CD8_TCELL_VS_NKCELL_UP | 180 | 41 | 17377 | 2626 |
TOMM20,LIME1,LYRM4,ST13,CASP6,DHPS,TMED3,DNAJB1,PABPC4,MEAF6,BCAT2,THAP4,GRSF1,RPL19,CNN2,FAM171A1,TACC3,ABCC1,MOSPD1,LDHB,PGAP2,CDKN2AIP,ATP13A1,OSBP2,PBXIP1,AMD1,RPS10,EZR,SRSF5,PRKRA,ODC1,ARHGAP15,GLOD4,AKAP1,ATP1A1,ERGIC3,EIF2D,CAB39,FKBP5,HIGD2A,USP13 |
| 4.009e-03 | -5.52 | GSE29618_PRE_VS_DAY7_FLU_VACCINE_BCELL_DN | MSigDB lists | GSE29618_PRE_VS_DAY7_FLU_VACCINE_BCELL_DN | 180 | 41 | 17377 | 2626 |
SLC30A9,PTTG1,ANK3,C5orf30,ARFIP2,SIRT2,THRAP3,TTF1,FBXO22,RPN2,MAST2,UBE3B,UBE3C,SAP30L,TACC3,ARHGAP17,SNRNP200,DCAF8,DHX29,ZMYM5,MKI67,TOP3A,HEBP2,LRRC1,FANCE,DHX57,ZFR,CBX3,ADSS,PPP2CA,TRAM2,DNAJC10,CDC16,PEX5,AGPAT2,PFDN4,DHX16,C1orf109,FTSJ1,COPS6,HEXA |
| 4.009e-03 | -5.52 | GSE6674_CPG_VS_CPG_AND_ANTI_IGM_STIM_BCELL_DN | MSigDB lists | GSE6674_CPG_VS_CPG_AND_ANTI_IGM_STIM_BCELL_DN | 180 | 41 | 17377 | 2626 |
SRM,SLC30A9,PRPF38B,NOP2,FAM129A,GADD45G,SLC2A1,ARID5A,ACAP1,CHIC2,AGPAT3,JMJD6,RLF,KCMF1,RHBDD1,PRNP,FKBP1A,PPP1R3B,SAR1A,SNX18,UTP18,ALDH18A1,SEH1L,SAP30,MOB4,BIRC3,FAM49B,ETV3,PFKFB3,MAP4K3,USP22,ZFAND5,LUC7L,MTMR3,SERTAD2,CDCA7L,NFIL3,CEBPG,FAF1,SMNDC1,PFKP |
| 4.009e-03 | -5.52 | GSE29617_CTRL_VS_DAY7_TIV_FLU_VACCINE_PBMC_2008_UP | MSigDB lists | GSE29617_CTRL_VS_DAY7_TIV_FLU_VACCINE_PBMC_2008_UP | 180 | 41 | 17377 | 2626 |
UBE2D3,CYTIP,FAM53C,CCZ1,ZNF416,YTHDF3,RGS2,RGS1,DNAJB9,RAVER2,SAP130,MEX3C,SIAH1,ZNF326,DCP1A,MAML1,RBM15,TIPARP,ETV3,TACC1,COQ10B,BTG2,KAT7,CUL3,MTMR6,PFKFB3,RAB1A,ZFAND5,ARL5B,RHOB,PWWP2B,RAB18,ZNF282,L3MBTL3,CCZ1B,MAFK,KLHL15,PITX1,NFIL3,ZMIZ1,SMNDC1 |
| 4.009e-03 | -5.52 | GSE3982_BASOPHIL_VS_CENT_MEMORY_CD4_TCELL_DN | MSigDB lists | GSE3982_BASOPHIL_VS_CENT_MEMORY_CD4_TCELL_DN | 180 | 41 | 17377 | 2626 |
SLC12A7,PRPF38B,PIGN,GGA1,CAST,ABCC10,MAN2B1,GGA2,RAPGEF6,SRRT,CPNE3,CD320,PRKD3,IARS,GOT2,SIVA1,TAF5L,NAP1L4,MYBL1,DNAL4,CDC37,KAT2A,PRRC2A,PPT1,ZNF202,WDR18,RPSA,MAT2A,USP36,NECAP2,ALG3,SGSH,CHD3,EIF2D,ITGB1,DCAF11,CHMP7,FAM208A,PRPF4B,POLQ,TMEM33 |
| 4.009e-03 | -5.52 | V$MAZ_Q6 | MSigDB lists | V$MAZ_Q6 | 180 | 41 | 17377 | 2626 |
RHOG,ZNF496,KDM4A,ZFP91,SLC2A1,TMEM109,ENSA,ARFIP2,THRAP3,FKBP2,LMNA,XPR1,CREM,PHC2,CSDE1,SHC1,SSBP3,ARHGEF2,UPF2,CAMK2G,PLK3,NRAS,TRIM8,MIER1,HNRNPF,POLR3GL,TOR1AIP2,ARID1A,UBE4B,KRTCAP2,EIF4G2,PATL1,NCDN,HMGN2,PTPRF,ATP1A1,GALNT2,AHNAK,HNRNPR,HPS5,ATXN7L2 |
| 4.009e-03 | -5.52 | GSE15330_HSC_VS_PRO_BCELL_DN | MSigDB lists | GSE15330_HSC_VS_PRO_BCELL_DN | 180 | 41 | 17377 | 2626 |
COX15,UBE2E2,NSMCE4A,RAC1,PMS2,STARD7,SIKE1,ABCB10,IFT27,PCBP1,SDHA,MYEF2,ERH,NEK6,RALB,BDH1,RPAP1,ANP32A,ALDH18A1,LPCAT1,TIPARP,TMEM9,TIMM50,NUDC,DCTN1,NIPSNAP1,ELOF1,MOB4,PRKDC,LDHA,ARHGDIB,ESYT1,FANCE,KLF6,SEPT1,SEC61A1,CTBS,NDUFS5,CHEK2,NDE1,HRAS |
| 4.009e-03 | -5.52 | GSE2770_IL12_AND_TGFB_ACT_VS_ACT_CD4_TCELL_2H_UP | MSigDB lists | GSE2770_IL12_AND_TGFB_ACT_VS_ACT_CD4_TCELL_2H_UP | 180 | 41 | 17377 | 2626 |
HSPH1,GCLM,ST13,PHF23,DYNLL1,GADD45G,TRIO,S1PR2,LMNA,ATP6V0B,ZBTB45,PSMD1,MED8,RNASEK,ZNF200,AKR1B1,TARDBP,ZNF189,ABCC1,METTL1,FTL,HPDL,RAB7A,ACSL3,TEX10,DNAJA1,EML4,FADD,RHEB,NMT2,CCDC127,PI4K2A,LEMD2,KEAP1,EIF4ENIF1,TPP2,MRPL27,PDXK,ZMIZ1,NRBP1,APOL2 |
| 4.009e-03 | -5.52 | GSE30971_WBP7_HET_VS_KO_MACROPHAGE_DN | MSigDB lists | GSE30971_WBP7_HET_VS_KO_MACROPHAGE_DN | 180 | 41 | 17377 | 2626 |
TRIP10,HLA-E,MED13L,CSNK2A1,DNAJB1,POFUT1,KTN1,TFRC,SLC25A37,EEF2K,RBM17,PTPN2,VAV1,RAB21,ASAP2,ITGB8,TNFAIP8,PTEN,FJX1,TP53BP2,LDLRAD3,STAT3,RNF169,ENPP4,ANKLE2,ETV3,MAP4K4,HEBP2,PFKFB3,MRPS10,PNPLA8,ARPC1A,KLF6,ZFR,SLCO4A1,GOLGA2,GADD45B,CAB39,FAM126A,MAP3K5,CDKN2A |
| 4.011e-03 | -5.52 | GO_NUCLEAR_TRANSCRIBED_MRNA_CATABOLIC_PROCESS_DEADENYLATION_DEPENDENT_DECAY | MSigDB lists | GO_NUCLEAR_TRANSCRIBED_MRNA_CATABOLIC_PROCESS_DEADENYLATION_DEPENDENT_DECAY | 53 | 16 | 17377 | 2626 |
EXOSC7,EXOSC6,EIF4A3,LSM6,EXOSC1,POLR2D,DCP1A,EXOSC9,CNOT6,CNOT6L,PARN,PATL1,PABPC1,PAIP1,CNOT3,EDC3 |
| 4.011e-03 | -5.52 | SESTO_RESPONSE_TO_UV_C2 | MSigDB lists | SESTO_RESPONSE_TO_UV_C2 | 53 | 16 | 17377 | 2626 |
TSTA3,TRIP10,ELL2,RAF1,CUL3,KIF5B,FNTA,ZKSCAN1,ATP13A3,SRSF4,YY1,USP11,CTDSP2,ZNF146,SRPK2,MORC3 |
| 4.016e-03 | -5.52 | GO_PROTEIN_DNA_COMPLEX_SUBUNIT_ORGANIZATION | MSigDB lists | GO_PROTEIN_DNA_COMPLEX_SUBUNIT_ORGANIZATION | 218 | 48 | 17377 | 2626 |
HJURP,UBN1,ARID2,SHPRH,CHD1L,CENPF,CTCF,SMARCA4,MIS12,OIP5,RPA2,XRCC2,RAD23B,XPA,H2AFY,CENPM,NAP1L4,GTF2H2,SMARCE1,HP1BP3,NASP,TSPYL4,RBX1,ARID1A,MCM2,ASF1B,CHAF1A,RPA1,SUPT16H,TAF2,PAF1,RAD51C,NAP1L1,BRD2,RPS27A,H2AFX,HMGB2,CABIN1,ANP32E,XRCC3,CENPT,RBBP4,H3F3A,NAA60,DDB1,IPO4,RAD51D,SMARCD1 |
| 4.026e-03 | -5.51 | BROWNE_HCMV_INFECTION_20HR_UP | MSigDB lists | BROWNE_HCMV_INFECTION_20HR_UP | 229 | 50 | 17377 | 2626 |
CCNC,THOC1,B4GALT5,CDK2AP2,PLAGL2,ARFIP2,SIKE1,TAF6L,ZNF267,PRKACA,SAFB2,LYN,SRRT,TFRC,NFATC3,AHCTF1,CDC42,RABGAP1L,TRMU,PTPN11,LTN1,UBE2M,CGGBP1,CDC5L,PRPF19,BAK1,ERF,ZNF202,DNAJA1,OGFR,MARK2,RHOB,TRIM26,ETS2,BRD2,DUSP3,E2F4,PML,SIAH2,H2AFX,ATXN2L,TRIM52,SRSF3,TFDP2,CHMP7,POT1,EYA2,CBX4,PRPF4B,DDX52 |
| 4.026e-03 | -5.51 | chr16p13 | MSigDB lists | chr16p13 | 229 | 50 | 17377 | 2626 |
USP7,RPS2,CORO7,ABCA3,TRAF7,TSC2,UBN1,FLYWCH2,CHTF18,PIGQ,RMI2,SNN,HCFC1R1,UBE2I,PARN,PDXDC1,POLR3K,TFAP4,SNRNP25,CLUAP1,GLIS2,ADCY9,ZNF200,TMEM8A,SPSB3,ABCC1,MLST8,PDPK1,NAGPA,TELO2,ZNF500,RNPS1,PKMYT1,AMDHD2,METTL22,MPG,CCNF,RHOT2,LUC7L,HAGH,GFER,ZNF174,AXIN1,TBL3,HAGHL,ATP6V0C,NDE1,ZNF75A,ZNF598,NAA60 |
| 4.031e-03 | -5.51 | MRPL48 (mitochondrial ribosomal protein L48) | protein interactions | 51642 | 33 | 12 | 17029 | 2761 |
MRPL50,SDHB,NIFK,MRPL9,MRPL42,MRPL55,MRPL39,GRSF1,MRPL12,LSM8,TARDBP,APP |
| 4.031e-03 | -5.51 | YME1L1 (YME1 like 1 ATPase) | protein interactions | 10730 | 33 | 12 | 17029 | 2761 |
UNK,DAP3,NDUFB6,PTEN,TIMMDC1,NDUFA11,ATP5F1A,APOOL,PSEN1,AP4E1,PHKG2,GEMIN7 |
| 4.031e-03 | -5.51 | SPC25 (SPC25, NDC80 kinetochore complex component) | protein interactions | 57405 | 33 | 12 | 17029 | 2761 |
GCC2,SEC61B,DSN1,SNAP29,MYO18A,LRPPRC,TKT,NUF2,PMF1,HDGFL2,KTN1,MIS12 |
| 4.031e-03 | -5.51 | NUSAP1 (nucleolar and spindle associated protein 1) | protein interactions | 51203 | 33 | 12 | 17029 | 2761 |
PPP1R12A,UGP2,PRDX3,HPDL,C5orf30,AP2B1,NUP153,UBE4B,CCNF,APP,CHAF1A,HP1BP3 |
| 4.031e-03 | -5.51 | SRP54 (signal recognition particle 54) | protein interactions | 6729 | 33 | 12 | 17029 | 2761 |
GEMIN5,TFAP4,PRKDC,SF3B6,RNPS1,DDX20,GEMIN4,SMC2,DUSP22,XRCC4,SMC4,CDC5L |
| 4.031e-03 | -5.51 | MBNL1 (muscleblind like splicing regulator 1) | protein interactions | 4154 | 33 | 12 | 17029 | 2761 |
HNRNPA2B1,RFWD3,DAP3,HNRNPH3,IDH3A,DHX9,IARS2,HNRNPF,AEN,DDX5,APP,DDX17 |
| 4.031e-03 | -5.51 | CTPS2 (CTP synthase 2) | protein interactions | 56474 | 33 | 12 | 17029 | 2761 |
SUGP1,OTUD5,METTL1,NUCB1,NASP,DHPS,PRKDC,CTPS1,EHD4,LRSAM1,KTN1,RPL23A |
| 4.031e-03 | -5.51 | APBB2 (amyloid beta precursor protein binding family B member 2) | protein interactions | 323 | 33 | 12 | 17029 | 2761 |
VAV1,APLP2,SYNCRIP,NCK1,GOPC,CBWD1,SMURF1,SMAD4,APP,APOL2,AKAP1,WDR41 |
| 4.031e-03 | -5.51 | KDM2A (lysine demethylase 2A) | protein interactions | 22992 | 33 | 12 | 17029 | 2761 |
RB1,PPP1R2,E2F1,UHRF2,KRAS,RANGAP1,RBPJ,MPG,ECPAS,REEP5,CBX4,PSMB3 |
| 4.032e-03 | -5.51 | GSE27859_CD11C_INT_F480_HI_MACROPHAGE_VS_CD11C_ING_F480_INT_DC_UP | MSigDB lists | GSE27859_CD11C_INT_F480_HI_MACROPHAGE_VS_CD11C_ING_F480_INT_DC_UP | 164 | 38 | 17377 | 2626 |
CTDP1,PIGN,GNPNAT1,GNE,PMS2,RAB23,SLC12A9,WRB,TRIM65,ANKRD26,SEC11A,DPYSL2,AHSA1,TBC1D14,MRPS27,EI24,GLE1,ALDH18A1,MOB1A,LPCAT1,MTX2,TMEM14C,CTDSP2,TPCN1,CAMK2G,HEMK1,GUK1,LRRC8A,OTUD3,FANCE,FADD,CDKN2AIPNL,SCAP,RAB24,CORO1C,MRPL27,SH3GLB2,NAA60 |
| 4.034e-03 | -5.51 | protein N-terminus binding | molecular function | GO:0047485 | 100 | 26 | 17224 | 2647 |
EIF5A,TGFB1,NCOR2,PHB2,MECP2,CSNK2A1,SMARCA4,MEN1,VPS25,BIRC2,HSPA1B,EPB41,RPA2,CALM2,TSC1,PDCD10,MDM2,PEX5,ACOX1,BANF1,EXOC4,RBPJ,NCOA1,GTF2H2,PDLIM5,SMARCE1 |
| 4.036e-03 | -5.51 | Retrograde transport at the Trans-Golgi-Network | REACTOME pathways | R-HSA-6811440 | 49 | 16 | 10287 | 1696 |
GCC2,RHOBTB3,SYS1,SCOC,VTI1A,COG1,ARFIP2,TGOLN2,RAB6A,STX16,RIC1,NAPG,GOLGA4,NSF,GCC1,NAA35 |
| 4.042e-03 | -5.51 | RAB5A (RAB5A, member RAS oncogene family) | protein interactions | 5868 | 119 | 31 | 17029 | 2761 |
KIF3B,UNK,TSC2,RAB11B,RAB7A,VPS45,MOGS,LDHA,HTATIP2,ARF1,RAB1A,DUSP22,RHOT2,RUFY1,RAB11A,RAB22A,CDC73,APPL1,RAB2B,SH3GLB1,RPN1,RAB8A,MKNK1,RAP1A,TBC1D17,DNAAF2,RAB4A,APPL2,ATE1,TAF12,LDHB |
| 4.052e-03 | -5.51 | mRNA 3'-end processing | REACTOME pathways | R-HSA-72187 | 62 | 19 | 10287 | 1696 |
SRSF11,FYTTD1,CDC40,SARNP,THOC1,SRSF6,RBM8A,RNPS1,SRSF5,DDX39A,SYMPK,SRSF1,PAPOLA,EIF4A3,SRSF4,SRSF3,CHTOP,CPSF4,CSTF1 |
| 4.052e-03 | -5.51 | Translation initiation complex formation | REACTOME pathways | R-HSA-72649 | 62 | 19 | 10287 | 1696 |
RPS15,EIF3L,RPS2,EIF3D,RPS10,RPS24,EIF4H,EIF3G,RPS9,RPSA,EIF3H,EIF3A,EIF3K,EIF2S2,RPS27A,RPS14,FAU,PABPC1,RPS26 |
| 4.053e-03 | -5.51 | FLECHNER_BIOPSY_KIDNEY_TRANSPLANT_REJECTED_VS_OK_DN | MSigDB lists | FLECHNER_BIOPSY_KIDNEY_TRANSPLANT_REJECTED_VS_OK_DN | 520 | 101 | 17377 | 2626 |
NDUFA5,IMMT,TOMM20,TXN,ST13,COPA,ANK3,CSNK2A1,EBNA1BP2,FKBP2,SNRPD3,OAT,SDHA,PRNP,DST,APLP2,ASAP2,ATP2A2,GOT2,MTMR4,HADHB,TECR,SPTSSA,MINPP1,CLTB,AHCYL1,F2R,ATF2,GPD1L,OGG1,STRAP,PCBP2,RHOBTB3,SLC16A7,VDAC2,PRKRA,RAB1A,VDAC1,H2AFV,PDHX,SRSF1,KRIT1,GLOD4,HSPA4,DDOST,TMED10,ATP6V0E1,SMAD4,PARD3,SEPHS2,KIF3B,NDUFS1,MUT,DAP,CYCS,NCKAP1,EPHX2,PDXDC1,DNAJB9,NDUFS4,SLC25A36,SLC31A1,CLIC4,ADD3,AHCY,NDUFS8,PTGES3,IMPA2,SLC25A1,ALDH9A1,SNX2,TSPYL4,ZMYND11,NQO2,FBXO9,HAGH,ECH1,ANKRD46,CYB5A,CAT,SDHB,FBXO21,GOLGA4,PRDX3,DUSP3,ACOX1,PARG,SETD3,BBX,FAM3C,PGRMC1,LRPPRC,CCDC69,ACAT1,MDH1,ACADM,RNF14,PDLIM5,TOB1,TERF1,GCSH |
| 4.058e-03 | -5.51 | Rnf111 (ring finger 111) | protein interactions | 93836 | 8 | 5 | 17029 | 2761 |
AP2B1,CSNK2A1,SMAD2,CBX4,SUMO2 |
| 4.058e-03 | -5.51 | Top3a (topoisomerase (DNA) III alpha) | protein interactions | 21975 | 8 | 5 | 17029 | 2761 |
RPA2,BLM,RMI1,RMI2,TOP3A |
| 4.058e-03 | -5.51 | SP6 (Sp6 transcription factor) | protein interactions | 80320 | 8 | 5 | 17029 | 2761 |
TRAF7,GNB2,CCZ1,RMC1,MYO18A |
| 4.058e-03 | -5.51 | PTGDR (prostaglandin D2 receptor) | protein interactions | 5729 | 8 | 5 | 17029 | 2761 |
GNAS,ANKRD13C,MAPK1,APP,MAPK3 |
| 4.058e-03 | -5.51 | AIFM3 (apoptosis inducing factor, mitochondria associated 3) | protein interactions | 150209 | 8 | 5 | 17029 | 2761 |
PPIF,LZTR1,APP,NMT2,PRNP |
| 4.058e-03 | -5.51 | C1orf122 (chromosome 1 open reading frame 122) | protein interactions | 127687 | 8 | 5 | 17029 | 2761 |
SNX2,SNAP29,SGF29,MRPL12,TXLNA |
| 4.058e-03 | -5.51 | Espn (espin) | protein interactions | 56226 | 8 | 5 | 17029 | 2761 |
TTC3,GOLGA4,RABGAP1L,IPO4,SMARCD1 |
| 4.058e-03 | -5.51 | Ankrd28 (ankyrin repeat domain 28) | protein interactions | 105522 | 8 | 5 | 17029 | 2761 |
ARHGEF2,PPP6R2,PPP6R3,PPP6R1,PPP6C |
| 4.058e-03 | -5.51 | INPP4A (inositol polyphosphate-4-phosphatase type I A) | protein interactions | 3631 | 8 | 5 | 17029 | 2761 |
SMAD1,CD81,WDYHV1,CAPN1,NXT2 |
| 4.058e-03 | -5.51 | TSR2 (TSR2, ribosome maturation factor) | protein interactions | 90121 | 8 | 5 | 17029 | 2761 |
USP39,DDX24,RPS26,BYSL,PIAS2 |
| 4.061e-03 | -5.51 | late endosome | cellular component | GO:0005770 | 239 | 51 | 18223 | 2701 |
RAB14,ANKRD27,CHMP2A,ANKRD13D,GNPNAT1,ANXA6,CCZ1,CDIP1,VTI1A,MON1B,LAMTOR3,TMEM165,RAB11A,WDR48,SPPL2A,SLC31A1,RAP1A,PIKFYVE,F2R,TMEM9,MYO5A,CLCN3,ATG9A,RAB7A,KCNQ1,WDR81,CHMP2B,RAB22A,MAP2K2,RHOB,RMC1,MAPK3,DERL1,SCARB2,OSBPL11,HGS,CHMP4A,VPS26B,LAMTOR4,VIPAS39,CHMP4B,VPS4A,CLN3,WDR91,MAPK1,ECPAS,CHID1,SNX14,VPS29,DYNC1LI2,STARD3NL |
| 4.061e-03 | -5.51 | ENTH_VHS | interpro domains | IPR008942 | 27 | 10 | 18492 | 2768 |
HGS,RPRD1A,CHERP,GGA1,U2SURP,EPN1,GGA2,STAM,RPRD1B,PICALM |
| 4.071e-03 | -5.50 | cullin-RING ubiquitin ligase complex | cellular component | GO:0031461 | 189 | 42 | 18223 | 2701 |
KLHL21,DCAF15,KCTD17,KLHL18,CUL1,MAD2L2,ZER1,DTL,KLHL5,KLHL20,DDA1,FBXO7,CDKN1B,FBXL7,ANAPC7,FBXL19,SPSB3,DCAF6,RBX1,DCAF8,CUL3,FBXO9,ANAPC2,CDC23,CCNF,PEF1,BTBD1,CAND1,PDCD6,CDC16,KEAP1,CDC27,KLHL15,KBTBD7,DCAF11,KLHL42,FBXL3,UBE2C,DCAF5,ANAPC4,DDB1,ZSWIM6 |
| 4.084e-03 | -5.50 | CCGNMNNTNACG_UNKNOWN | MSigDB lists | CCGNMNNTNACG_UNKNOWN | 72 | 20 | 17377 | 2626 |
TTPAL,ZCCHC9,GGNBP2,WDR1,BTAF1,SIKE1,CYCS,GNB2,WDR48,TMEM179B,ZER1,SYNCRIP,VMP1,CEP55,AP1M1,TRA2B,CAB39,VCPIP1,MRPL40,ZBTB11 |
| 4.095e-03 | -5.50 | GO_CENTROSOME_CYCLE | MSigDB lists | GO_CENTROSOME_CYCLE | 44 | 14 | 17377 | 2626 |
KIF3B,CCP110,CENPJ,TUBGCP5,PKD2,CNTROB,CEP63,BRCA1,WDR62,NDE1,SASS6,CDK2,KIF11,TUBGCP2 |
| 4.095e-03 | -5.50 | MODULE_87 | MSigDB lists | MODULE_87 | 44 | 14 | 17377 | 2626 |
GNAS,GNA12,RAB8A,RAP1A,NRAS,CDC42,SUCLG1,RALB,ARF5,RIT1,ARF1,RAB11A,RHEB,ARF4 |
| 4.097e-03 | -5.50 | phagocytosis | biological process | GO:0006909 | 190 | 43 | 17256 | 2622 |
WASF2,RHOG,RAB14,TM9SF4,RAC1,ACTR3,VAV2,TMX3,MYH9,JMJD6,CDC42SE2,NCKAP1,CSNK1A1,LYN,BECN1,PIP5K1C,VAV1,CDC42,ARPC5,SH3BP1,PIK3R2,DNM2,CORO1A,PDIA6,ABI1,CYFIP1,NCK1,RAB7A,WIPF1,EIF2AK1,CYFIP2,ARPC1A,MAPK3,SCARB2,WAS,ELMO1,CORO1C,LIMK1,ACTB,SCARB1,MAPK1,ABCA1,ANXA11 |
| 4.098e-03 | -5.50 | GSE19401_UNSTIM_VS_PAM2CSK4_STIM_FOLLICULAR_DC_DN | MSigDB lists | GSE19401_UNSTIM_VS_PAM2CSK4_STIM_FOLLICULAR_DC_DN | 191 | 43 | 17377 | 2626 |
MEF2A,MRPL19,PRPF18,ATG4A,CAPN2,FANCL,RB1,DECR1,SP100,GRSF1,NUP153,PDIA6,UBE2M,MTX2,CGGBP1,KLF10,GUK1,ELL2,CREG1,PGGT1B,GMFB,MRPL12,HTATIP2,CHMP2B,FXR1,ARPC1A,PDHX,ISG15,NEU1,CHAF1A,MAP3K4,NUCB1,BRD2,CCDC86,CDC27,TIMM17A,TFDP1,MAPK6,RGL1,PDCD11,XRCC4,HEXA,TOB1 |
| 4.098e-03 | -5.50 | GSE23308_CTRL_VS_CORTICOSTERONE_TREATED_MACROPHAGE_DN | MSigDB lists | GSE23308_CTRL_VS_CORTICOSTERONE_TREATED_MACROPHAGE_DN | 191 | 43 | 17377 | 2626 |
MBD1,NOP2,TRIP10,MRPS2,TBC1D13,KIF2C,LYN,SAC3D1,GTF2F1,RAP1A,VASP,TNFAIP8,IARS,ARPC5,RALB,TANK,SLC44A1,CLDND1,PCYT2,MVP,FGFR1OP2,CARM1,FDFT1,PDPK1,FAM49B,NCK1,RAD51AP1,OAF,PSPC1,POLR2D,GORASP2,DNAJA1,STK17B,LSG1,PPP2CA,SURF4,TAB2,PPP1R11,AEN,DUSP11,ACTB,MRPL3,AP2S1 |
| 4.098e-03 | -5.50 | GSE26030_UNSTIM_VS_RESTIM_TH17_DAY15_POST_POLARIZATION_DN | MSigDB lists | GSE26030_UNSTIM_VS_RESTIM_TH17_DAY15_POST_POLARIZATION_DN | 191 | 43 | 17377 | 2626 |
RAB14,HLA-E,CCM2,TMEM109,MCCC1,TKT,ASAH1,DNAJB1,CDIPT,DCUN1D4,CSNK1A1,MAP1LC3B,PIP4K2A,DNAJB9,FERMT3,RAB21,ATP2A2,CDKN1B,TAGLN2,GNAI2,CTDSP2,DCTN1,PRPF19,RYBP,ELOVL5,EID1,ERF,BMS1,MCL1,DNAJA1,OGFR,TRIM28,SF3A2,RPSA,DDX17,SCARB2,HIPK2,CEP55,ZNF436,NUP62,CHMP4B,ATP6V0C,OAZ1 |
| 4.104e-03 | -5.50 | GGA1 (golgi associated, gamma adaptin ear containing, ARF binding protein 1) | protein interactions | 26088 | 72 | 21 | 17029 | 2761 |
CLCN3,GGA1,AKT2,CSNK2A1,ARF1,GGA2,SYNRG,TOLLIP,STAM,APP,DHX15,NECAP2,SLC38A7,RPS27A,FAAP100,ARF5,RABGAP1L,TFDP1,EXOC4,DNM2,CDKN2A |
| 4.104e-03 | -5.50 | SNX1 (sorting nexin 1) | protein interactions | 6642 | 72 | 21 | 17029 | 2761 |
TK1,NASP,SNX2,AGTRAP,GSPT2,ARFIP2,CCNL2,MCM2,STAM,APP,MAT2B,HGS,MLX,VPS26B,STAT1,ARL6IP1,RUVBL2,ATP6V1C1,F2R,RTN3,VPS29 |
| 4.104e-03 | -5.50 | THRB (thyroid hormone receptor beta) | protein interactions | 7068 | 72 | 21 | 17029 | 2761 |
NCOR2,NRAS,TRIP12,TRIP10,PRKDC,CTCF,HMGN3,UBE2I,PRMT2,MPG,XRCC5,RXRB,HSPA4,GPS2,MECR,ANP32A,ACTB,NCOA1,ATF2,NCOA2,HDAC2 |
| 4.104e-03 | -5.50 | HYOU1 (hypoxia up-regulated 1) | protein interactions | 10525 | 72 | 21 | 17029 | 2761 |
DNAJC2,EWSR1,GBA,DNAJC9,BRCA1,DNAJA1,DNAJB1,MCM2,ATP6V1B2,EXT2,NUP205,XRCC5,RFWD3,DNAJC8,DNAJC17,H2AFX,SEL1L,CLU,CDK2,MSH6,DCTN1 |
| 4.104e-03 | -5.50 | TCOF1 (treacle ribosome biogenesis factor 1) | protein interactions | 6949 | 72 | 21 | 17029 | 2761 |
PPT1,HPDL,CSNK2A1,BRCA1,PRKRA,BECN1,PIP4K2A,WDR48,RPA1,CAND1,UBTF,RPA2,NDUFV1,PCNA,SEPT11,POLR1B,CDK2,ARRB2,TERF2,SRPK2,SRSF10 |
| 4.106e-03 | -5.50 | Cellular Senescence | REACTOME pathways | R-HSA-2559583 | 196 | 47 | 10287 | 1696 |
H2AFZ,TXN,UBN1,RPS6KA1,SUZ12,MAPK14,ETS1,PHC2,TERF2IP,CDKN2C,RB1,MDM2,CCNA2,CDKN1B,ANAPC7,STAT3,TERF2,ERF,MAPKAPK3,MAP4K4,EHMT1,E2F3,ANAPC2,CDC23,H2AFV,MAPK3,CDC16,CDC27,ETS2,RPS27A,TFDP1,H2AFX,E2F1,CABIN1,MAP3K5,TFDP2,RBBP4,H3F3A,CDK2,E2F2,UBE2C,MAPK1,TERF1,POT1,CBX4,ANAPC4,CDKN2A |
| 4.113e-03 | -5.49 | Signaling of Hepatocyte Growth Factor Receptor | WikiPathways | WP313 | 34 | 12 | 5312 | 837 |
CRKL,RAP1A,PTEN,RAF1,PTPN11,ITGB1,ELK1,STAT3,MAPK1,HRAS,MAP2K2,MAPK3 |
| 4.121e-03 | -5.49 | transcription factor activity, RNA polymerase II transcription factor binding | molecular function | GO:0001076 | 188 | 43 | 17224 | 2647 |
RORB,POU3F2,ZNF296,TRERF1,DHX9,SMARCA4,MED13L,MEF2A,THRAP3,NOTCH2,DNAJB1,SNAPC4,CDC73,TTF1,WWP2,MED8,MED10,CITED2,CREB1,ATF2,MYBL1,MED22,CARM1,CDC5L,POU2AF1,RIOX2,MYBL2,WBP2,RTF1,BRCA1,SOX4,TRIM28,TAF2,HIPK2,PITX1,ARNTL,MED15,NCOA1,BEND6,YY1,SMAD4,SGF29,N4BP2L2 |
| 4.123e-03 | -5.49 | BABAM1 (BRISC and BRCA1 A complex member 1) | protein interactions | 29086 | 63 | 19 | 17029 | 2761 |
PLK1,USP7,NDUFA5,UBXN1,RANGAP1,BRCA1,DDX39A,PARK7,ARF4,TERF2IP,BABAM2,PCNA,NSF,SPATA2,ABRAXAS2,PRDX5,VPS4A,TFG,DEF6 |
| 4.133e-03 | -5.49 | mannosidase activity | molecular function | GO:0015923 | 15 | 7 | 17224 | 2647 |
MAN2A2,MAN2B1,EDEM2,MANBA,MAN1B1,MAN1A1,USF3 |
| 4.142e-03 | -5.49 | SAP_dom | interpro domains | IPR003034 | 23 | 9 | 18492 | 2768 |
SARNP,RAD18,SAFB,HNRNPUL2,PIAS2,SAFB2,SLTM,CCAR1,SF3B2 |
| 4.144e-03 | -5.49 | GO_LYTIC_VACUOLE | MSigDB lists | GO_LYTIC_VACUOLE | 497 | 97 | 17377 | 2626 |
ANKRD27,RAB14,AGRN,TSC2,TRIP10,ABCC10,ANK3,HEXB,TMEM97,RRAGC,GYG1,AP1B1,ATP6V1B2,LYN,GNB2,USP5,NAPG,AP1M1,CLCN6,AKR1B1,AP2B1,MARCH2,TMEM9,TMBIM1,GM2A,DRAM2,ATP6V1G1,WDR41,MIOS,PPT1,GOPC,RAB7A,LRBA,SLC17A5,CHMP2B,RHEB,PON2,AHNAK,WDR11,NAGLU,AP1S1,ATP6V0C,SCARB1,VPS4A,CLN3,AP2S1,CHID1,CAPN1,ANXA11,STARD3NL,DNAJC5,ANXA6,CCZ1,MANBA,SRGN,FLOT1,LAMTOR3,SDC2,ASAH1,MAN2B1,TMEM165,PSEN1,WDR48,SPPL2A,CAPN2,GNS,CTSS,ZNRF2,ATP6V0A2,TMEM8A,TPCN1,ATP6V0D1,MYO5A,ACP2,TNFAIP3,GALC,GBA,RFFL,ADRB2,KCNQ1,SPPL2B,NEU1,PI4K2A,CAT,SCARB2,SGSH,ATP6V1D,NSF,CCZ1B,SNAP23,CTBS,CTSA,PSAP,ATP6V1C1,HEXA,SNX14,ZC3HAV1 |
| 4.144e-03 | -5.49 | GRAESSMANN_RESPONSE_TO_MC_AND_DOXORUBICIN_UP | MSigDB lists | GRAESSMANN_RESPONSE_TO_MC_AND_DOXORUBICIN_UP | 585 | 112 | 17377 | 2626 |
ZNF296,PPP1R37,NAT9,TMEM184B,TRIM11,HEXB,ZFYVE21,GLUD1,ABCB10,IKBIP,BRIX1,UBE2I,TWF2,SLC20A1,RNF103,ATP6V0B,MDM2,ATG3,DNM2,AKR1B1,CORO1A,NAA35,TMBIM1,TACC3,PPIF,PSRC1,BTG2,CPOX,LACTB,CIRBP,DNAJC9,SLC25A22,PRKRA,ICMT,STK17B,STOML2,ABHD5,ANKRD10,TMEM41A,AHNAK,SURF4,PDRG1,NDUFA11,STAT1,SH3GLB2,ST3GAL2,TRIM32,SPRYD4,SCARB1,NCOA1,PPP5C,GLCCI1,ZMAT3,SLC12A7,SEPHS2,LZTR1,MAPRE1,DNAJB2,TOR3A,CDK2AP2,MAN2B1,MXD4,DNAJB1,LANCL1,GGA2,IFT27,DNAJB9,SAC3D1,SRXN1,GNS,RB1,PDXP,SLC31A1,NFATC3,ZNRF2,CRAT,PTPN11,EI24,DAPK1,GTSE1,CTR9,ACAD8,RNF135,FRMD8,ATP6V0D1,MSH6,AMPD2,TRAFD1,RNASEH2C,SNX2,POLK,EMP3,ADRB2,PLEC,KLF6,HAGH,RBM38,HSPA1B,RXRB,FAS,ATP6V1D,PDLIM1,FAM110A,ERGIC3,EXOC4,E2F1,USP20,CENPT,EHD4,PDLIM5,HRAS,ALS2 |
| 4.148e-03 | -5.49 | KMT2A (lysine methyltransferase 2A) | protein interactions | 4297 | 100 | 27 | 17029 | 2761 |
EWSR1,CXXC1,PPIE,KRAS,WDR5,MEN1,CBFB,KIF11,MBD3,SYMPK,CDC73,POLR2A,DOT1L,PAF1,AFDN,CHD3,E2F4,CTR9,AFF1,MAP3K5,H3F3A,RBBP4,E2F2,TAF6,CBX4,HDAC2,SAP30 |
| 4.148e-03 | -5.49 | MAGEA11 (MAGE family member A11) | protein interactions | 4110 | 100 | 27 | 17029 | 2761 |
EWSR1,BIRC3,GNPDA1,WDYHV1,ILF3,CSNK2A1,BIRC2,MAPK3,UTP25,DNAJC10,RB1,RBM23,CLUAP1,SUV39H2,RBL1,PRDX3,CCDC14,IL6ST,MTA1,COX7A2L,E2F1,USP20,NDUFB9,FKBP5,NSUN4,NCOA2,EGLN1 |
| 4.148e-03 | -5.49 | HNRNPAB (heterogeneous nuclear ribonucleoprotein A/B) | protein interactions | 3182 | 100 | 27 | 17029 | 2761 |
UNK,COX15,STAU1,CYLD,EWSR1,IVNS1ABP,VHL,PTTG1,CUL3,CUL1,BRCA1,MCM2,SF3A2,RPA1,CAND1,HNRNPA2B1,RPA2,AHNAK,SYNCRIP,SNAP23,H2AFX,YBX1,ACTB,TARDBP,COPS6,SMURF1,LDHB |
| 4.154e-03 | -5.48 | PID_ATM_PATHWAY | MSigDB lists | PID_ATM_PATHWAY | 31 | 11 | 17377 | 2626 |
MDM2,SMC3,H2AFX,TOP3A,DCLRE1C,CHEK2,BRCA1,BLM,XRCC4,TRIM28,TERF2 |
| 4.154e-03 | -5.48 | PID_SYNDECAN_2_PATHWAY | MSigDB lists | PID_SYNDECAN_2_PATHWAY | 31 | 11 | 17377 | 2626 |
TGFB1,RHOA,NF1,ITGB1,SDC2,EZR,MAPK1,PRKACA,HRAS,MAPK3,EPB41 |
| 4.154e-03 | -5.48 | GO_REGULATION_OF_VIRAL_RELEASE_FROM_HOST_CELL | MSigDB lists | GO_REGULATION_OF_VIRAL_RELEASE_FROM_HOST_CELL | 31 | 11 | 17377 | 2626 |
CHMP2A,TRIM8,TRIM26,TRIM11,PML,CHMP4B,TRIM32,VPS4A,CHMP2B,TRIM28,DDB1 |
| 4.154e-03 | -5.48 | GO_CENTROSOME_DUPLICATION | MSigDB lists | GO_CENTROSOME_DUPLICATION | 31 | 11 | 17377 | 2626 |
CCP110,CENPJ,TUBGCP5,PKD2,CNTROB,CEP63,WDR62,NDE1,SASS6,CDK2,TUBGCP2 |
| 4.160e-03 | -5.48 | cellular response to abiotic stimulus | biological process | GO:0071214 | 289 | 61 | 17256 | 2622 |
RAB11B,RAC1,HABP4,SLC2A1,TMEM109,BCL2L1,EIF2AK4,BLM,MAPK14,METTL3,RHBDD1,MDM2,PCNA,PTEN,INTS7,TANK,RCSD1,XPA,NOC2L,DNM2,AKR1B1,ARHGEF2,CRY2,CNN2,MAP3K14,MTPN,SPIDR,EEF1D,PTPRK,CHP1,BAK1,TGFB1,ERCC1,POLK,NET1,AKT2,RAD51AP1,PBK,AURKB,ELK1,RHOB,FADD,FAS,RDH11,XRCC5,MAPK3,ADSS,MBIP,ATP1A1,NSMF,H2AFX,CAB39,PKD2,STK11,CHEK2,PIEZO1,RUVBL2,YY1,HRAS,DDB1,IFI16 |
| 4.160e-03 | -5.48 | cellular response to environmental stimulus | biological process | GO:0104004 | 289 | 61 | 17256 | 2622 |
RAB11B,RAC1,HABP4,SLC2A1,TMEM109,BCL2L1,EIF2AK4,BLM,MAPK14,METTL3,RHBDD1,MDM2,PCNA,PTEN,INTS7,TANK,RCSD1,XPA,NOC2L,DNM2,AKR1B1,ARHGEF2,CRY2,CNN2,MAP3K14,MTPN,SPIDR,EEF1D,PTPRK,CHP1,BAK1,TGFB1,ERCC1,POLK,NET1,AKT2,RAD51AP1,PBK,AURKB,ELK1,RHOB,FADD,FAS,RDH11,XRCC5,MAPK3,ADSS,MBIP,ATP1A1,NSMF,H2AFX,CAB39,PKD2,STK11,CHEK2,PIEZO1,RUVBL2,YY1,HRAS,DDB1,IFI16 |
| 4.167e-03 | -5.48 | GSE45739_NRAS_KO_VS_WT_UNSTIM_CD4_TCELL_DN | MSigDB lists | GSE45739_NRAS_KO_VS_WT_UNSTIM_CD4_TCELL_DN | 175 | 40 | 17377 | 2626 |
GOLPH3L,TRERF1,TCF3,TIA1,RACGAP1,DAZAP2,ETS1,PARN,RCOR3,STAM,RNF103,JMY,CDK5,DECR1,ADD3,SLC1A4,SIAH1,CTDSP2,GM2A,PCBP2,KDELR1,VPS13B,CLCN3,GALC,PBXIP1,DENND4C,C14orf132,ZFAND5,PHF6,ARHGAP15,NMT2,AMZ2,SCARB2,PPP2R5A,CHD3,PTER,CTBS,STAT1,TFDP2,LTA4H |
| 4.170e-03 | -5.48 | GO_S_ADENOSYLMETHIONINE_DEPENDENT_METHYLTRANSFERASE_ACTIVITY | MSigDB lists | GO_S_ADENOSYLMETHIONINE_DEPENDENT_METHYLTRANSFERASE_ACTIVITY | 112 | 28 | 17377 | 2626 |
METTL1,ASH1L,DNMT3A,NOP2,CXXC1,NSUN2,EHMT1,METTL2A,WDR82,EZH1,ICMT,WDR5,MEN1,PRMT2,METTL3,MTR,DOT1L,IRF4,SUV39H2,METTL14,SETD3,CAMKMT,WDR4,PRMT7,FBL,DNMT1,FTSJ3,CARM1 |
| 4.170e-03 | -5.48 | protein serine/threonine phosphatase activity | molecular function | GO:0004722 | 71 | 20 | 17224 | 2647 |
CTDP1,PPP3CA,MTMR6,CYCS,PPP3CB,UBLCP1,MTMR3,PPP2CA,MTMR4,PTEN,PPM1G,PPP6C,PPP3R1,PPA2,PPP5C,PPP2R2D,CTDSP2,ILKAP,CAMK2G,TIMM50 |
| 4.176e-03 | -5.48 | GSE6259_FLT3L_INDUCED_DEC205_POS_DC_VS_CD8_TCELL_DN | MSigDB lists | GSE6259_FLT3L_INDUCED_DEC205_POS_DC_VS_CD8_TCELL_DN | 159 | 37 | 17377 | 2626 |
DDX58,PARP12,SND1,CFLAR,HERC3,CWC27,CENPJ,ETV6,TPST1,SGCB,STAT3,PPA1,TRIM14,ATP13A1,CSRP1,TMEM39A,TOR1AIP2,SLC25A22,IL12RB1,AZI2,OGFR,FOXRED1,PSMB9,ISG15,TRIM26,KEAP1,CERS6,NLRC5,PML,STAT1,NAA20,WDR91,EHD4,TRAF5,LRP8,ZC3HAV1,RNF114 |
| 4.187e-03 | -5.48 | GO_CHAPERONE_BINDING | MSigDB lists | GO_CHAPERONE_BINDING | 77 | 21 | 17377 | 2626 |
BAK1,ST13,DNAJB2,SDF2L1,DNAJA1,DNAJB1,SYVN1,OGDH,TFRC,PRNP,HLA-B,TSC1,DNAJC10,ATP1A1,BIRC5,PFDN4,AHSA1,CDKN1B,CLU,CDC37,USP13 |
| 4.189e-03 | -5.48 | GO_GLYCOSYLATION | MSigDB lists | GO_GLYCOSYLATION | 246 | 53 | 17377 | 2626 |
GXYLT1,GORASP1,PRKCSH,B4GALT5,TRAK1,MOGS,B4GALT1,SIRT2,SDF2L1,B4GALT4,PSEN1,TMEM165,EXT2,POFUT1,MAN1A1,TET3,RPN1,C1GALT1,NUS1,DAD1,FUT8,RPN2,OSTC,LMAN1,ST8SIA2,SLC35C2,TIPARP,MGAT5,NAGPA,B3GALT6,TMEM115,DPM1,MAN1B1,PARP4,SYVN1,GALNT7,MCFD2,EDEM2,SERP1,ARF4,MAN2A2,ALG3,GALNT2,DDOST,GOLGA2,MAGT1,STT3A,OGT,ST3GAL2,GALNT10,B4GALT3,PARP10,B4GALT2 |
| 4.190e-03 | -5.48 | FXR2 (FMR1 autosomal homolog 2) | protein interactions | 9513 | 129 | 33 | 17029 | 2761 |
EWSR1,SUZ12,MECP2,PRKAA1,CSNK2A1,MEAF6,ARL6IP1,AP1M1,ZBTB22,TERF2,SRPK2,CYFIP1,CUL3,MRPL43,C1orf35,BRCA1,MPG,CYFIP2,FXR1,BTBD1,CAND1,PAF1,MBIP,MFAP1,SNAP23,RBMX,CEP55,YWHAH,COIL,RTN3,SSSCA1,BYSL,IFI16 |
| 4.190e-03 | -5.48 | CBX8 (chromobox 8) | protein interactions | 57332 | 129 | 33 | 17029 | 2761 |
USP7,NIFK,NOP2,SUZ12,YTHDC2,CSNK2A1,KRR1,PHC2,KRI1,CMSS1,YBX1,FBL,FTSJ3,PPAN,CCDC57,STAU1,HMGN5,BAZ2A,KAT7,GTPBP4,ILF3,PSMB7,PCGF6,BCLAF1,PCGF1,ZFR,GOLGA2,RPS14,NFIL3,USP11,PDCD11,ZC3HAV1,CBX4 |
| 4.193e-03 | -5.47 | positive regulation of organelle assembly | biological process | GO:1902117 | 67 | 19 | 17256 | 2622 |
PDCD6IP,RHOA,SEPT9,KCTD17,PIP4K2C,SEPT7,BECN1,PIP4K2A,SH3GLB1,SPAG5,CCP110,RALB,CENPJ,STX18,NUP62,CNOT6,CNOT6L,LRSAM1,ATMIN |
| 4.194e-03 | -5.47 | Thioredoxin_domain | interpro domains | IPR013766 | 40 | 13 | 18492 | 2768 |
TXNL1,DNAJC10,TXN,TXNDC16,PRDX3,TMX4,PRDX5,TMX3,PDIA6,GLRX3,QSOX2,TMX1,PRDX1 |
| 4.226e-03 | -5.47 | MAP3K5 (mitogen-activated protein kinase kinase kinase 5) | protein interactions | 4217 | 86 | 24 | 17029 | 2761 |
TXN,TNFAIP3,RB1CC1,RAF1,APP,PARK7,PSMC4,FAS,GEMIN5,GNA12,PDCD6,HSPA4,SIAH1,QARS,GADD45B,PTPN11,PPP3R1,YWHAZ,MAP3K5,PPP5C,ARRB2,YWHAH,TRAF5,PSMC1 |
| 4.226e-03 | -5.47 | MSH6 (mutS homolog 6) | protein interactions | 2956 | 86 | 24 | 17029 | 2761 |
UNK,CYLD,CLSPN,POLK,PRKDC,PMS2,CUL3,CSNK2A1,BRCA1,BLM,ATP6V1B2,PRDX1,CHAF1A,XRCC5,SUPT16H,DTL,DECR1,PCNA,SMC3,POLE,ZNF746,MSH2,H3F3A,CDC5L |
| 4.226e-03 | -5.47 | RTCB (RNA 2',3'-cyclic phosphate and 5'-OH ligase) | protein interactions | 51493 | 86 | 24 | 17029 | 2761 |
UNK,COX15,CYLD,PRKDC,MTA2,DHX9,CUL3,CUL1,MTMR12,VDAC1,C2orf49,RFC2,ABCF1,APPL1,MATR3,CAND1,PPP1R8,QARS,DNM2,FUS,ECPAS,HNRNPM,PTOV1,CDC5L |
| 4.226e-03 | -5.47 | MED26 (mediator complex subunit 26) | protein interactions | 9441 | 86 | 24 | 17029 | 2761 |
CCNC,CTDP1,POLR2I,EWSR1,POLR2G,POLR2L,POLR2K,ELL2,ELOA,POLR2D,MED13L,EAF2,POLR2A,MASTL,TAF2,MED8,MED10,POLR2J,MED15,AFF1,ICE2,TCEA1,TAF6,MED22 |
| 4.227e-03 | -5.47 | REACTOME_SIGNALING_BY_FGFR | MSigDB lists | REACTOME_SIGNALING_BY_FGFR | 107 | 27 | 17377 | 2626 |
PDPK1,NRAS,TSC2,AKT2,RAF1,PRKAR1B,KRAS,AKT1S1,PRKACA,FOXO3,MAP2K2,MAPK3,PPP2CA,CALM2,MKNK1,FGFR3,MDM2,SHC1,PTEN,RPS27A,ADCY9,CDKN1B,CREB1,MAPK1,HRAS,ADCY7,MLST8 |
| 4.238e-03 | -5.46 | positive regulation of ATPase activity | biological process | GO:0032781 | 53 | 16 | 17256 | 2622 |
DNAJC2,DNAJB2,DYNLL1,TOR1AIP1,DHX9,DNAJC24,DNAJC9,TOR1AIP2,DNAJB1,DNAJA1,DNAJC10,AHSA1,RAB4A,DNM2,CHTOP,DNAL4 |
| 4.238e-03 | -5.46 | amino acid activation | biological process | GO:0043038 | 53 | 16 | 17256 | 2622 |
KARS,LARS,HARS,MRPL39,POLG2,TARS,EPRS,FARSA,GATC,IARS,QARS,IARS2,PPA2,QRSL1,PPA1,CARS2 |
| 4.242e-03 | -5.46 | core promoter binding | molecular function | GO:0001047 | 141 | 34 | 17224 | 2647 |
H2AFZ,AGO2,DHX9,SMARCA4,THRAP3,FOXO3,PARK7,RRN3,NRF1,RB1,MTA1,ZNF335,H2AFY,CCAR1,POU2AF1,ZFP64,KLF10,BAZ2A,PSPC1,E2F3,WBP2,SOX4,KDM3A,UBTF,SAFB,RBMX,ARNTL,STAT1,NLRC5,E2F1,RUVBL2,H3F3A,E2F2,IFI16 |
| 4.244e-03 | -5.46 | YWHAH (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta) | protein interactions | 7533 | 230 | 53 | 17029 | 2761 |
TSC2,NF1,TWNK,RAE1,RAF1,KIF23,FOXO3,DTL,FAM192A,KIF5B,MEX3C,HUWE1,MTMR4,CENPJ,HDAC7,CDKN1B,ARHGEF2,PCYT2,CDC25B,TP53BP2,MOB1A,EIF5,NSUN4,NCOA2,PDPK1,CYFIP1,ERMP1,TNFAIP3,KIAA0930,CUL3,MCM2,CYFIP2,MARK2,OPTN,EVC2,TSC1,NEK1,CLK3,PIAS2,YWHAZ,TRIM32,NCOA1,DMWD,PTPDC1,MAP3K5,WDR62,REEP4,CDK2,ARRB2,YWHAH,FAM83G,PARD3,PTOV1 |
| 4.245e-03 | -5.46 | GTSE1 (G2 and S-phase expressed 1) | protein interactions | 51512 | 134 | 34 | 17029 | 2761 |
PKP4,THOC1,POC1A,MYH9,EPN1,AP1B1,CSNK1A1,SEC16A,PRKACA,SYNRG,SCYL2,REPS1,CDC42,SEC24C,AP1M1,AP2B1,MVP,CLTB,CARM1,DCTN1,USO1,RAB7A,CAPZA2,ERBIN,ANLN,RAB1A,PICALM,SMAP2,CDC16,GOLGA2,KBTBD7,AP1S1,USP11,NUMB |
| 4.255e-03 | -5.46 | chromatin assembly or disassembly | biological process | GO:0006333 | 185 | 42 | 17256 | 2622 |
HJURP,UBN1,ARID2,SHPRH,SMARCA4,CTCF,OIP5,SUV39H2,NOC2L,H2AFY,ANP32A,CENPM,NAP1L4,SMARCE1,TNRC18,HP1BP3,NASP,TSPYL4,MTA2,PBRM1,ARID1A,MCM2,ASF1B,CENPU,SUPT16H,CHAF1A,PAF1,NAP1L1,BRD2,CHD3,H2AFX,BAZ1B,ANP32E,HMGB2,CABIN1,CENPT,H3F3A,RBBP4,NAA60,IPO4,CDKN2A,SMARCD1 |
| 4.258e-03 | -5.46 | SIT4 (type 2A-related serine/threonine-protein phosphatase SIT4) | protein interactions | 851513 | 3 | 3 | 17029 | 2761 |
PPP6R3,PPP6R2,PPP6R1 |
| 4.258e-03 | -5.46 | TPI1P1 (triosephosphate isomerase 1 pseudogene 1) | protein interactions | 729708 | 3 | 3 | 17029 | 2761 |
CUL1,EWSR1,HUWE1 |
| 4.258e-03 | -5.46 | OCM2 (oncomodulin 2) | protein interactions | 4951 | 3 | 3 | 17029 | 2761 |
TERF2IP,TERF1,TERF2 |
| 4.258e-03 | -5.46 | HMGB1P10 (high mobility group box 1 pseudogene 10) | protein interactions | 100130561 | 3 | 3 | 17029 | 2761 |
TFAP4,EWSR1,CAND1 |
| 4.258e-03 | -5.46 | CDC42EP5 (CDC42 effector protein 5) | protein interactions | 148170 | 3 | 3 | 17029 | 2761 |
SEPT7,CDC42,PTEN |
| 4.258e-03 | -5.46 | UBBP4 (ubiquitin B pseudogene 4) | protein interactions | 23666 | 3 | 3 | 17029 | 2761 |
CYLD,MCM2,MCM5 |
| 4.258e-03 | -5.46 | LPAR3 (lysophosphatidic acid receptor 3) | protein interactions | 23566 | 3 | 3 | 17029 | 2761 |
GNAI2,APP,LMNA |
| 4.258e-03 | -5.46 | TCF7 (transcription factor 7) | protein interactions | 6932 | 3 | 3 | 17029 | 2761 |
SS18L1,DAZAP2,ZMIZ1 |
| 4.258e-03 | -5.46 | CBWD6 (COBW domain containing 6) | protein interactions | 644019 | 3 | 3 | 17029 | 2761 |
CBWD1,CBWD2,HDAC7 |
| 4.258e-03 | -5.46 | FAM161B (FAM161B, centrosomal protein) | protein interactions | 145483 | 3 | 3 | 17029 | 2761 |
SMAD2,ACAD8,KLHL15 |
| 4.258e-03 | -5.46 | C19orf33 (chromosome 19 open reading frame 33) | protein interactions | 64073 | 3 | 3 | 17029 | 2761 |
APP,DVL2,XIAP |
| 4.258e-03 | -5.46 | ADGRG1 (adhesion G protein-coupled receptor G1) | protein interactions | 9289 | 3 | 3 | 17029 | 2761 |
KRAS,ADRB2,ARRB2 |
| 4.258e-03 | -5.46 | THAP9 (THAP domain containing 9) | protein interactions | 79725 | 3 | 3 | 17029 | 2761 |
MRPL50,MRPL9,KCTD17 |
| 4.258e-03 | -5.46 | Haus3 (HAUS augmin-like complex, subunit 3) | protein interactions | 231123 | 3 | 3 | 17029 | 2761 |
PLK1,PPP1R12A,VDAC1 |
| 4.258e-03 | -5.46 | HIST1H4G (histone cluster 1 H4 family member g) | protein interactions | 8369 | 3 | 3 | 17029 | 2761 |
H2AFZ,AGTRAP,LMNA |
| 4.258e-03 | -5.46 | UL21A (facilitates viral DNA synthesis) | protein interactions | 3077448 | 3 | 3 | 17029 | 2761 |
ANAPC7,CDC23,CDC27 |
| 4.258e-03 | -5.46 | GPR84 (G protein-coupled receptor 84) | protein interactions | 53831 | 3 | 3 | 17029 | 2761 |
CERS6,REEP5,LMBR1 |
| 4.258e-03 | -5.46 | APOA5 (apolipoprotein A5) | protein interactions | 116519 | 3 | 3 | 17029 | 2761 |
RAB5B,SMARCD1,FAS |
| 4.258e-03 | -5.46 | SPATA4 (spermatogenesis associated 4) | protein interactions | 132851 | 3 | 3 | 17029 | 2761 |
BRCA1,SIAH1,APP |
| 4.258e-03 | -5.46 | Dnmt3a (DNA methyltransferase 3A) | protein interactions | 13435 | 3 | 3 | 17029 | 2761 |
SMARCA4,PTGES3,DYNLL1 |
| 4.259e-03 | -5.46 | REACTOME_PROLONGED_ERK_ACTIVATION_EVENTS | MSigDB lists | REACTOME_PROLONGED_ERK_ACTIVATION_EVENTS | 19 | 8 | 17377 | 2626 |
KRAS,RAP1A,NRAS,MAPK1,HRAS,RAF1,MAP2K2,MAPK3 |
| 4.259e-03 | -5.46 | GO_ERROR_PRONE_TRANSLESION_SYNTHESIS | MSigDB lists | GO_ERROR_PRONE_TRANSLESION_SYNTHESIS | 19 | 8 | 17377 | 2626 |
RPA2,PCNA,RFC3,RFC2,POLK,RPS27A,MAD2L2,RPA1 |
| 4.259e-03 | -5.46 | COLLIS_PRKDC_SUBSTRATES | MSigDB lists | COLLIS_PRKDC_SUBSTRATES | 19 | 8 | 17377 | 2626 |
CTDP1,SNRNP200,DCLRE1C,XRCC4,POLR2A,RPA1,XRCC5,H2AFX |
| 4.259e-03 | -5.46 | REACTOME_LAGGING_STRAND_SYNTHESIS | MSigDB lists | REACTOME_LAGGING_STRAND_SYNTHESIS | 19 | 8 | 17377 | 2626 |
POLA2,RPA2,PCNA,RFC3,PRIM2,RFC2,PRIM1,RPA1 |
| 4.259e-03 | -5.46 | GO_REGULATION_OF_SPINDLE_ORGANIZATION | MSigDB lists | GO_REGULATION_OF_SPINDLE_ORGANIZATION | 19 | 8 | 17377 | 2626 |
PLK1,CHMP2A,CHMP4B,PSRC1,PDCD6IP,CHMP2B,BORA,TPX2 |
| 4.259e-03 | -5.46 | GO_GAMMA_TUBULIN_COMPLEX | MSigDB lists | GO_GAMMA_TUBULIN_COMPLEX | 19 | 8 | 17377 | 2626 |
MZT2A,MZT1,CENPJ,TUBGCP5,TOPORS,BRCA1,TUBGCP2,MZT2B |
| 4.268e-03 | -5.46 | GSE4748_CTRL_VS_CYANOBACTERIUM_LPSLIKE_STIM_DC_1H_UP | MSigDB lists | GSE4748_CTRL_VS_CYANOBACTERIUM_LPSLIKE_STIM_DC_1H_UP | 186 | 42 | 17377 | 2626 |
C9orf78,C19orf53,KIAA0100,NOP2,CASP6,EBNA1BP2,NENF,GTF3A,UBQLN2,B4GALT4,SPR,RLF,ZADH2,PHC2,KRI1,FEM1B,AP2B1,CFL1,EEF1D,ATP6V1G1,KDM3B,AMPD2,TMEM115,SIGMAR1,CDC123,OXR1,TOPORS,PLEC,PRPSAP1,TARS,SUPT16H,YIF1A,PRDX3,PDRG1,NDUFA11,COX8A,SIL1,CAB39,DNAJC30,SLC22A23,TSTD2,TSPAN5 |
| 4.268e-03 | -5.46 | GSE43863_LY6C_INT_CXCR5POS_VS_LY6C_LOW_CXCR5NEG_EFFECTOR_CD4_TCELL_UP | MSigDB lists | GSE43863_LY6C_INT_CXCR5POS_VS_LY6C_LOW_CXCR5NEG_EFFECTOR_CD4_TCELL_UP | 186 | 42 | 17377 | 2626 |
WASF2,HECA,PLXNC1,FAM129A,TCF3,CERK,B4GALT1,LYN,CPNE3,TMCC3,PPP1R3B,VASP,KDM2A,WDR44,BDH1,FUT8,BCL2,TAGLN2,CREB1,PIKFYVE,LPCAT1,SMARCE1,PPP3CA,CYTH1,BIRC3,TACC1,KIAA0040,PBXIP1,ANKRD33B,KCNQ1,ARID1A,PDE3B,STK17B,VEZF1,RAB18,TSC1,CSK,SNAP29,NRM,UHRF2,RBMS1,BEND6 |
| 4.268e-03 | -5.46 | GSE40274_GATA1_VS_FOXP3_AND_GATA1_TRANSDUCED_ACTIVATED_CD4_TCELL_DN | MSigDB lists | GSE40274_GATA1_VS_FOXP3_AND_GATA1_TRANSDUCED_ACTIVATED_CD4_TCELL_DN | 186 | 42 | 17377 | 2626 |
SRM,ZNF207,PHB2,MAGED1,UCK2,BCL2L1,SLC35B1,PPP1R16B,EEF2K,FBRS,LYAR,RB1,SNX18,MCM5,ZNHIT6,LPIN2,SLC12A2,FBXL19,MGAT5,PPA1,N4BP2,MSH6,GINS1,UBQLN4,HEMK1,OAF,EHMT1,E2F3,SREK1,DCTD,NUTF2,VDAC1,DDX39A,RFC2,AKAP1,TBL3,LIMK1,GADD45B,ARNTL,GLCCI1,CD81,CSNK1D |
| 4.268e-03 | -5.46 | GSE22886_NAIVE_BCELL_VS_BM_PLASMA_CELL_UP | MSigDB lists | GSE22886_NAIVE_BCELL_VS_BM_PLASMA_CELL_UP | 186 | 42 | 17377 | 2626 |
FGFR1OP,GGA1,MRPL39,MANBA,GSPT2,RBM8A,MYNN,GMCL1,NOTCH2,ZNF267,ATP6V1B2,CRLF3,PARN,COMMD8,NUP205,WDR48,CREM,CCP110,ZCCHC2,TIMELESS,CORO1A,MAVS,TPCN1,TERF2,NASP,SEPT9,LRBA,RPL38,KCTD20,SMC2,OTUD3,MCM2,EML4,SUPT16H,PRIM1,CAT,HHEX,FBXO28,PARG,STAT6,DTX4,POT1 |
| 4.268e-03 | -5.46 | GSE17721_POLYIC_VS_GARDIQUIMOD_4H_BMDC_UP | MSigDB lists | GSE17721_POLYIC_VS_GARDIQUIMOD_4H_BMDC_UP | 186 | 42 | 17377 | 2626 |
MBD1,TCF12,MRI1,RACGAP1,TAF6L,GGA2,SLC12A9,IFT27,STMN1,BIRC2,RB1,MBD2,PPCDC,TIMELESS,NUP153,PLCL2,CTDSP2,TPCN1,SRPK2,FTL,ATP13A1,HEMK1,KAT2A,NEK7,PRKDC,SLC25A22,KRTCAP2,KLF6,PRPSAP1,NECAP2,HLA-B,DAP3,ATP6V1D,RBM47,BRD2,VPS26B,SNAP29,QARS,TOMM6,CDCA5,MPV17,PDXK |
| 4.268e-03 | -5.46 | GSE17721_LPS_VS_PAM3CSK4_12H_BMDC_DN | MSigDB lists | GSE17721_LPS_VS_PAM3CSK4_12H_BMDC_DN | 186 | 42 | 17377 | 2626 |
IVNS1ABP,STARD7,CLCC1,OAT,GLRX3,SDHA,POLR3K,PNO1,CD320,EBP,PRKD3,BANF1,BDH1,ARHGEF1,MECR,RPF2,ECD,RNF26,TALDO1,SLC35A1,HDHD2,S100A6,SMC4,ABCC1,SEC61B,RAB7A,SEPT8,ARHGEF12,RPL27A,MAT2A,CYB5A,TMEM41A,BIRC5,NIP7,TOMM6,ACOX1,FAM3C,DBI,COX8A,CHEK2,MRPL3,SLC25A33 |
| 4.268e-03 | -5.46 | GSE3982_EOSINOPHIL_VS_CENT_MEMORY_CD4_TCELL_DN | MSigDB lists | GSE3982_EOSINOPHIL_VS_CENT_MEMORY_CD4_TCELL_DN | 186 | 42 | 17377 | 2626 |
TCF12,PRPF38B,ABCA3,ANXA6,HJURP,CAST,MRPL39,MUM1,HABP4,CUL1,COX4I1,CD320,CAPN2,CLUAP1,PRKD3,ADD3,LRRC8D,GRSF1,IL6ST,MRPL34,COPS7B,NAP1L4,UBE3C,TFG,TRIM14,NIPSNAP1,TSTA3,ZBED5,UBE4B,FXR1,USP21,CAND1,RPL36,MAP3K4,DAP3,EIF2D,IARS2,ITGB1,TCOF1,COPS6,MRPL3,HIGD2A |
| 4.271e-03 | -5.46 | KEEN_RESPONSE_TO_ROSIGLITAZONE_DN | MSigDB lists | KEEN_RESPONSE_TO_ROSIGLITAZONE_DN | 102 | 26 | 17377 | 2626 |
CYTIP,CLCN3,PKP4,TXN,GMFG,CSRP1,DNAJB2,DYNLL1,SRGN,EMP3,MEF2A,DAZAP2,RGS2,MATR3,MAT2B,CTSS,PTEN,GADD45B,CAPZA1,ACTB,CLU,PTGES3,GNAI2,S100A6,CGGBP1,SLC25A1 |
| 4.271e-03 | -5.46 | RICKMAN_TUMOR_DIFFERENTIATED_WELL_VS_MODERATELY_UP | MSigDB lists | RICKMAN_TUMOR_DIFFERENTIATED_WELL_VS_MODERATELY_UP | 102 | 26 | 17377 | 2626 |
ENPP4,ZNF207,UBL3,KAT7,ANKH,TMX4,JTB,EZH1,GGA2,EDEM2,ASXL2,EML4,USP21,HEATR5B,NCOA1,CLN3,GLCCI1,CHPT1,GPD1L,TRAF5,CNPY3,EYA2,FAM171A1,PDCD4,ABCC5,USP34 |
| 4.274e-03 | -5.46 | cytoplasmic ribonucleoprotein granule | cellular component | GO:0036464 | 195 | 43 | 18223 | 2701 |
SARNP,RAC1,HABP4,AGO2,PMS2,DHX9,TIA1,PCBP1,RBM4,PABPC4,CNOT3,EDC3,PSMA6,CDC42,DCP1A,UPF2,TAF5L,YBX1,CHTOP,PABPC1,SAMD4B,STAU1,POLR2G,EID1,NSUN2,RPL6,POLR2D,CIRBP,FXR1,PATL1,BTBD1,CNOT9,UPF1,EIF4ENIF1,LSM6,ARNTL,ATXN2L,PQBP1,KHSRP,ACTB,SNRPG,ROCK1,TUBB |
| 4.299e-03 | -5.45 | MTAP (methylthioadenosine phosphorylase) | protein interactions | 4507 | 50 | 16 | 17029 | 2761 |
ANXA6,FAM49B,LYRM1,UROD,CUTA,MCM2,RAB1A,ARF4,HINT1,CNN2,FUS,TAGLN2,TALDO1,MTPN,LYPLA2,CFL1 |
| 4.299e-03 | -5.45 | ASB6 (ankyrin repeat and SOCS box containing 6) | protein interactions | 140459 | 50 | 16 | 17029 | 2761 |
CORO7,RPRD1A,POLR2L,POLR2J,L3MBTL3,UBR2,ATIC,POLR2D,EZR,SLC25A5,RPRD1B,APP,GNB2,NMT2,POLR2A,MCTS1 |
| 4.299e-03 | -5.45 | TUFT1 (tuftelin 1) | protein interactions | 7286 | 50 | 16 | 17029 | 2761 |
OIP5,CCDC93,NSMCE4A,MAX,RPRD1A,GRIPAP1,RABGAP1L,ARNTL,SMC6,RCOR1,NUF2,CREB1,PSMD9,GIT2,HMG20A,BIRC2 |
| 4.299e-03 | -5.45 | MAPK10 (mitogen-activated protein kinase 10) | protein interactions | 5602 | 50 | 16 | 17029 | 2761 |
CDK5,CDKN2C,SH3BP5,CCT2,LDHA,EZR,CDKN1B,MCL1,DDX5,PKMYT1,ELK1,WDR62,ARRB2,ATF2,APP,CDKN2A |
| 4.299e-03 | -5.45 | NOC3L (NOC3 like DNA replication regulator) | protein interactions | 64318 | 50 | 16 | 17029 | 2761 |
SRP72,NOP2,DDX24,DGCR8,RBM34,TBL3,ZNF746,USP39,EBNA1BP2,PRKRA,FBL,BRIX1,MAK16,GPATCH4,IFI16,PNO1 |
| 4.299e-03 | -5.45 | USP13 (ubiquitin specific peptidase 13) | protein interactions | 8975 | 50 | 16 | 17029 | 2761 |
RPP25,CYLD,ATXN3,SMC3,SYNCRIP,THOC1,PTEN,STAT1,ACLY,SIAH2,DVL1,OGDH,UBE3C,NPLOC4,USP5,RAD23A |
| 4.299e-03 | -5.45 | LSM3 (LSM3 homolog, U6 small nuclear RNA and mRNA degradation associated) | protein interactions | 27258 | 50 | 16 | 17029 | 2761 |
RBM8A,ILF3,LSM8,NSD3,PRPF3,SNRPD3,BECN1,HAUS2,CLNS1A,SF3B2,CLIC4,KEAP1,LSM6,MAP4,YBX1,SNRPG |
| 4.299e-03 | -5.45 | MRM3 (mitochondrial rRNA methyltransferase 3) | protein interactions | 55178 | 50 | 16 | 17029 | 2761 |
MRPL42,MRPL39,ZNF512,LAMTOR3,CUL1,USP39,ORC1,LUC7L,APP,CAND1,MRPL50,PTPN2,GRSF1,PTER,KLHL42,SMNDC1 |
| 4.299e-03 | -5.45 | ERCC6 (ERCC excision repair 6, chromatin remodeling factor) | protein interactions | 2074 | 50 | 16 | 17029 | 2761 |
USP7,HMGN1,MPHOSPH8,XAB2,BRCA1,POLR2A,RPA1,CAND1,PCNA,MDM2,XPA,BAZ1B,CHEK2,COPS6,OGG1,DDB1 |
| 4.299e-03 | -5.45 | COX2 (cytochrome c oxidase subunit II) | protein interactions | 4513 | 50 | 16 | 17029 | 2761 |
SDHB,RPN1,COX5B,NDUFV2,COA3,NDUFS1,DDOST,MAGT1,ZNF746,VDAC2,PSMA1,COX4I1,VDAC1,CDK2,BCAP31,SSR1 |
| 4.303e-03 | -5.45 | BYSTRYKH_HEMATOPOIESIS_STEM_CELL_AND_BRAIN_QTL_CIS | MSigDB lists | BYSTRYKH_HEMATOPOIESIS_STEM_CELL_AND_BRAIN_QTL_CIS | 58 | 17 | 17377 | 2626 |
SCOC,AGTRAP,HARS,ZFP91,KLC1,GLO1,NDUFA7,ZFAND5,GFER,PDXDC1,NECAP2,PTPRF,GEMIN5,DAP3,DDA1,ARL6IP1,ALDH9A1 |
| 4.303e-03 | -5.45 | BACOLOD_RESISTANCE_TO_ALKYLATING_AGENTS_DN | MSigDB lists | BACOLOD_RESISTANCE_TO_ALKYLATING_AGENTS_DN | 58 | 17 | 17377 | 2626 |
PTTG1IP,TRIM28,SRSF1,VEZF1,EPRS,PDCD6,OGT,CS,LRPPRC,KHSRP,MEGF9,PRPF4,TCEA1,H3F3A,PURA,TUBB,ZC3HAV1 |
| 4.307e-03 | -5.45 | regulation of DNA-templated transcription, elongation | biological process | GO:0032784 | 44 | 14 | 17256 | 2622 |
PAF1,HMGN1,BRD4,THOC1,ZMYND11,AXIN1,LDB1,ZNF326,CTR9,RTF1,CDC73,GTF2F1,IWS1,SUPT16H |
| 4.320e-03 | -5.44 | BIRC2 (baculoviral IAP repeat containing 2) | protein interactions | 329 | 144 | 36 | 17029 | 2761 |
USP7,UBE2D3,CYLD,TOMM20,WDYHV1,DNAJB2,RAF1,UBXN1,RAC1,DHX9,XIAP,BIRC2,MXD1,UBE2Q2,CDC42,TANK,FBXO7,MAVS,MAP3K14,GCC1,HTRA2,PACS2,RHOA,TNFAIP3,BIRC3,WDR1,ILF3,UBE2V1,WDR82,BOLA1,EAF2,TOLLIP,BIRC5,PRDX3,E2F1,TRIM32 |
| 4.321e-03 | -5.44 | GSE21033_1H_VS_24H_POLYIC_STIM_DC_DN | MSigDB lists | GSE21033_1H_VS_24H_POLYIC_STIM_DC_DN | 154 | 36 | 17377 | 2626 |
RRP15,RPS6KA1,PRKAA1,HEXB,RPL15,AGFG1,COMMD5,ABHD14A,RNASEK,SUCLG2,OSTF1,TAGLN2,MRPL48,TECR,EEF1D,NOL12,RPL29,MLEC,MFNG,CYP20A1,PSMG1,PDE3B,PSMB9,RFC2,SLC25A5,SMAP2,EIF3H,PSMB3,PRDX3,WDR59,COX7A2L,SMAD1,RPS26,EYA2,IPO4,HIGD2A |
| 4.321e-03 | -5.44 | GSE3920_IFNA_VS_IFNG_TREATED_ENDOTHELIAL_CELL_UP | MSigDB lists | GSE3920_IFNA_VS_IFNG_TREATED_ENDOTHELIAL_CELL_UP | 154 | 36 | 17377 | 2626 |
FAM208B,DNAJC5,DNAJB2,SF3B1,NKRF,CCNL2,CDK11B,SAFB2,MXD1,JMY,CHKA,CREM,HOMER1,EIF5,RBM15,YTHDC1,PLK3,TNFAIP3,ELL2,ERF,BTG2,TOR1AIP2,FAM133B,ADRB2,ARL5B,POLG2,DOT1L,PAF1,TMEM54,LUC7L3,UHRF2,DDX5,SAMD8,CPEB2,ZC3HAV1,CWC25 |
| 4.328e-03 | -5.44 | MicroRNA (miRNA) biogenesis | REACTOME pathways | R-HSA-203927 | 25 | 10 | 10287 | 1696 |
POLR2I,POLR2G,POLR2L,POLR2J,DGCR8,POLR2K,AGO2,POLR2D,PRKRA,POLR2A |
| 4.328e-03 | -5.44 | GSE27291_0H_VS_7D_STIM_GAMMADELTA_TCELL_DN | MSigDB lists | GSE27291_0H_VS_7D_STIM_GAMMADELTA_TCELL_DN | 170 | 39 | 17377 | 2626 |
MAX,NF1,ADAM10,KIF23,TOP2B,DUSP22,PIP4K2A,MEAF6,TFRC,PHC2,MEX3C,WDR44,ZNRF2,SEPT11,TARDBP,MAML1,C16orf72,DENND1B,BTG2,DENND4C,SLC26A6,LNX2,ESYT1,ARMC8,SF3A2,PLEKHF2,ABHD5,FAS,MRPL2,OSBPL8,RBMX,GADD45B,RNF38,PTPN7,MEGF9,USP20,PITRM1,ZBTB11,CSNK1D |
| 4.334e-03 | -5.44 | CDC6 association with the ORC:origin complex | REACTOME pathways | R-HSA-68689 | 11 | 6 | 10287 | 1696 |
CDC6,ORC1,ORC3,E2F2,E2F1,E2F3 |
| 4.334e-03 | -5.44 | Condensation of Prometaphase Chromosomes | REACTOME pathways | R-HSA-2514853 | 11 | 6 | 10287 | 1696 |
CSNK2A1,SMC2,CCNB1,NCAPG,CCNB2,SMC4 |
| 4.337e-03 | -5.44 | energy coupled proton transmembrane transport, against electrochemical gradient | biological process | GO:0015988 | 31 | 11 | 17256 | 2622 |
ATP6V0B,ATP1A1,ATP5MC3,ATP6V0A2,ATP6V0A1,ATP6V0C,ATP6V1C1,ATP6V1B2,ATP6V0E1,ATP6V0D1,NDUFS7 |
| 4.337e-03 | -5.44 | negative regulation of cyclin-dependent protein serine/threonine kinase activity | biological process | GO:0045736 | 31 | 11 | 17256 | 2622 |
PLK1,TFAP4,CDKN2C,HHEX,TNFAIP3,PTEN,FBXO7,CDKN1B,MEN1,NR2F2,CDKN2A |
| 4.337e-03 | -5.44 | negative regulation of macroautophagy | biological process | GO:0016242 | 31 | 11 | 17256 | 2622 |
TSC1,UBQLN4,CHMP4A,FEZ2,TSC2,TIGAR,PHF23,CHMP4B,BECN1,HTRA2,USP36 |
| 4.337e-03 | -5.44 | multivesicular body organization | biological process | GO:0036257 | 31 | 11 | 17256 | 2622 |
CHMP2A,CHMP4A,HGS,PDCD6IP,CHMP4B,VPS4A,CHMP2B,CHMP7,RAB11A,STAM,VPS25 |
| 4.337e-03 | -5.44 | centrosome duplication | biological process | GO:0051298 | 31 | 11 | 17256 | 2622 |
CCP110,CENPJ,TUBGCP5,PKD2,CEP63,CNTROB,NDE1,WDR62,SASS6,CDK2,TUBGCP2 |
| 4.337e-03 | -5.44 | positive regulation of peptidyl-lysine acetylation | biological process | GO:2000758 | 31 | 11 | 17256 | 2622 |
TGFB1,KAT2A,KAT7,PRKAA1,WBP2,BRD7,RUVBL2,BRCA1,SOX4,SMAD4,MAPK3 |
| 4.339e-03 | -5.44 | regulation of protein modification process | biological process | GO:0031399 | 1804 | 313 | 17256 | 2622 |
FGFR1OP,TXN,TSC2,MAP3K7CL,XIAP,CCNL2,CCNB1,UBE2I,PPP1R16B,PARK7,EEF2K,CALM2,CDK5,CDKN2C,FIZ1,CRY2,FNIP2,CDC25B,PLCL2,DNMT1,MLST8,BAK1,AKT2,PBK,MRNIP,TOPORS,DCUN1D5,EIF3A,IWS1,MAP3K4,BRMS1,HHEX,RPS27A,LIMK1,AXIN1,OGT,ARRB2,HDAC2,PDCD4,SVIP,PPIB,HSPH1,CLSPN,GMFG,PHF23,GADD45G,PRKAA1,EIF2AK4,NOTCH2,PSEN1,VPS25,WDR48,CFLAR,DDRGK1,NDUFS4,TFAP4,FKBP1A,FBXO7,PPP4R1,MYDGF,MVP,GNAI2,PPP6R1,SOCS5,RB1CC1,MAPKAPK3,ZMYND11,GTPBP4,ADRB2,PTTG1IP,KDM3A,MAP2K2,FAS,XRCC5,DERL1,HSPBP1,FNTA,GOLGA2,DUSP3,CSK,QARS,FAM83D,CABIN1,PPP6R3,MAP3K5,RNF139,ALS2,CDKN2A,KARS,PPP1R37,GGNBP2,RAF1,MAGED1,RAC1,TPX2,CREBL2,DAZAP2,PRKACA,APP,TERF2IP,CRKL,SHC1,RALB,MTA1,ADCY9,SOCS6,NSFL1C,CDKN1B,MAVS,GPD1L,CDK12,PDCL3,ADCY7,ANKLE2,SHOC2,PSRC1,BRD4,EID1,KAT7,MAP4K4,TAOK1,WBP2,CUL3,ELP4,CDCA2,PKMYT1,DNAJA1,RAB1A,SOCS7,PPP2CA,PPP2R5A,CORO1C,HIPK2,RPLP1,TICAM1,PPP5C,LRP8,CSNK1D,RPS2,ZFP91,MECP2,FLOT1,AKT1S1,BLM,HMG20A,MAD2L2,PPP1R3B,CCNK,PDCD10,PTEN,PPP1R8,PTPN11,AXIN2,FEM1B,MAP3K14,PDPK1,ZFP64,KAT2A,TNFAIP3,JTB,MARK2,PRDX1,SH3BP5,HGS,GPS2,PARG,PML,PPP1R11,PSAP,CD81,PARP10,IGBP1,FAF1,CCNC,ZBED3,NF1,KMT2E,PPP1R15B,FAM129A,ENSA,NENF,SIRT2,S1PR2,MAPK14,BIRC2,FANCI,PRNP,ZER1,RAP1A,IL6ST,PIK3R2,NOC2L,CDC37,PLK1,COPS8,NCK1,GMFB,EZR,CDC6,UBE2V1,LRP5,BRCA1,SOX4,PAF1,SOCS4,ADAM9,CAB39,STK11,CHEK2,ROCK1,DVL1,CLU,PPP1R2,PPP1R12A,GORASP1,PHB2,DNAJB2,UBXN1,LAMTOR3,CIB1,RGS2,RB1,ZNF335,CTR9,BCL2,MDFIC,OXR1,GBA,RTF1,MAP4K3,EIF2AK1,KRAS,ISG15,MASTL,MBIP,TSC1,NSMF,SIAH2,NUP62,RUVBL2,EHD4,BCCIP,ASH1L,TRAF7,FOXM1,LYN,DUSP22,RPL11,UBXN2A,PPME1,KIF14,PIN1,AKAP8,TARDBP,CHTOP,F2R,STRAP,ABI1,CTDSP2,DVL2,CHP1,SNX25,TIMP2,BIRC3,TOLLIP,PEF1,DNAJC10,TAB2,UBXN2B,STK38,ARNTL,GADD45B,MAPK1,SMAD4,PPP2R2D,PARD3,MIF,TRIP12,DCUN1D4,FBXO5,PTPN2,FGFR3,TANK,DUS2,BRD7,ARHGEF2,H2AFY,ATG13,STAT3,TGFB1,TELO2,PPP1R9B,RHOA,ADAM17,PRKDC,PRKAR1B,MEN1,SYMPK,HSPA1B,MAPK3,CNOT9,LEMD2,NEK1,PDCD6,PLAA,TWSG1,OSBPL8,KMT2B,PKD2,NR2F2,UBE2C,HRAS,HIPK3 |
| 4.340e-03 | -5.44 | GSE35685_CD34POS_CD10NEG_CD62LPOS_VS_CD34POS_CD10POS_BONE_MARROW_DN | MSigDB lists | GSE35685_CD34POS_CD10NEG_CD62LPOS_VS_CD34POS_CD10POS_BONE_MARROW_DN | 197 | 44 | 17377 | 2626 |
MIF,SLC12A7,CASP6,SLC41A1,GADD45G,TAP1,ALKBH5,ENSA,ARFIP2,AGFG1,SLC35B1,AP1B1,SEC16A,CMTM6,BZW2,MXD1,ABHD16A,FARSA,MLX,TNFAIP8,VMP1,TBC1D14,TPST1,STAT3,MAP4K4,ATP6V0A1,RAB1A,KRTCAP2,LY6E,ZFAND5,PSMB9,SNRPA,ISG15,BOLA3,OSBPL11,NSF,STAT1,RWDD4,PML,ADAM9,ATF6,ATP6V0C,B4GALT3,RAB3IL1 |
| 4.341e-03 | -5.44 | Glioma | KEGG pathways | hsa05214 | 64 | 19 | 7161 | 1149 |
NRAS,RAF1,AKT2,E2F3,KRAS,MAP2K2,MAPK3,CALM2,RB1,MDM2,SHC1,PTEN,PIK3R2,E2F1,E2F2,MAPK1,HRAS,CDKN2A,CAMK2G |
| 4.341e-03 | -5.44 | Glioma | KEGG pathways | ko05214 | 64 | 19 | 7161 | 1149 |
NRAS,RAF1,AKT2,E2F3,KRAS,MAP2K2,MAPK3,CALM2,RB1,MDM2,SHC1,PTEN,PIK3R2,E2F1,E2F2,MAPK1,HRAS,CDKN2A,CAMK2G |
| 4.345e-03 | -5.44 | SUV39H1 (suppressor of variegation 3-9 homolog 1) | protein interactions | 6839 | 169 | 41 | 17029 | 2761 |
INTS2,MBD1,USP7,DNMT3A,MECP2,CDC73,MBD4,RB1,MDM2,LHX8,KLHL20,PTEN,ABRAXAS2,MCMBP,DNMT1,ELOF1,USP34,PRIM2,DCAF8,NFATC2,CDC23,KIF11,CDCA4,MID1IP1,CLK3,RBL1,CDCA7L,ZNF436,PML,ATE1,CABIN1,RUVBL2,KLHDC4,FUS,SMAD1,RBBP4,H3F3A,PSMC1,CBX4,HDAC2,ZBTB24 |
| 4.351e-03 | -5.44 | Derlin-1 retrotranslocation complex | cellular component | GO:0036513 | 12 | 6 | 18223 | 2701 |
DERL1,SYVN1,RNF139,RNF5,SEL1L,SVIP |
| 4.351e-03 | -5.44 | Gemini of coiled bodies | cellular component | GO:0097504 | 12 | 6 | 18223 | 2701 |
GEMIN6,GEMIN5,DDX20,GEMIN4,HABP4,GEMIN7 |
| 4.351e-03 | -5.44 | ESCRT III complex | cellular component | GO:0000815 | 12 | 6 | 18223 | 2701 |
CHMP2A,CHMP4B,VPS4A,CHMP4A,CHMP2B,CHMP7 |
| 4.353e-03 | -5.44 | SURP | prosite domains | PS50128 | 6 | 4 | 12060 | 1670 |
SUGP1,CHERP,SUGP2,U2SURP |
| 4.353e-03 | -5.44 | DIX | prosite domains | PS50841 | 6 | 4 | 12060 | 1670 |
DVL1,AXIN1,DVL2,AXIN2 |
| 4.353e-03 | -5.44 | ZF_TFIIS_2 | prosite domains | PS51133 | 6 | 4 | 12060 | 1670 |
POLR2I,TCEA1,ZNRD1,POLR3K |
| 4.353e-03 | -5.44 | ZF_TFIIS_1 | prosite domains | PS00466 | 6 | 4 | 12060 | 1670 |
POLR2I,TCEA1,ZNRD1,POLR3K |
| 4.356e-03 | -5.44 | REACTOME_THE_ROLE_OF_NEF_IN_HIV1_REPLICATION_AND_DISEASE_PATHOGENESIS | MSigDB lists | REACTOME_THE_ROLE_OF_NEF_IN_HIV1_REPLICATION_AND_DISEASE_PATHOGENESIS | 27 | 10 | 17377 | 2626 |
ELMO1,RAC1,AP1M1,AP1S1,AP2B1,PACS1,ARF1,AP1B1,AP2S1,HLA-A |
| 4.356e-03 | -5.44 | REACTOME_EXTENSION_OF_TELOMERES | MSigDB lists | REACTOME_EXTENSION_OF_TELOMERES | 27 | 10 | 17377 | 2626 |
POLA2,RPA2,RFC3,PCNA,POLE,PRIM2,RUVBL2,RFC2,PRIM1,RPA1 |
| 4.356e-03 | -5.44 | REACTOME_PIP3_ACTIVATES_AKT_SIGNALING | MSigDB lists | REACTOME_PIP3_ACTIVATES_AKT_SIGNALING | 27 | 10 | 17377 | 2626 |
PDPK1,MDM2,TSC2,PTEN,AKT2,CDKN1B,AKT1S1,CREB1,FOXO3,MLST8 |
| 4.356e-03 | -5.44 | GO_CLATHRIN_ADAPTOR_COMPLEX | MSigDB lists | GO_CLATHRIN_ADAPTOR_COMPLEX | 27 | 10 | 17377 | 2626 |
GGA1,AP3M2,AP1M1,AP1S1,AP2B1,AP1B1,GGA2,SYNRG,PICALM,AP2S1 |
| 4.356e-03 | -5.44 | GENTILE_UV_RESPONSE_CLUSTER_D9 | MSigDB lists | GENTILE_UV_RESPONSE_CLUSTER_D9 | 27 | 10 | 17377 | 2626 |
NAP1L1,CCNA2,KIAA0232,TMEM97,DNAJB1,RBPJ,TRIM32,CITED2,RRS1,LPCAT1 |
| 4.356e-03 | -5.44 | BIOCARTA_CREB_PATHWAY | MSigDB lists | BIOCARTA_CREB_PATHWAY | 27 | 10 | 17377 | 2626 |
GNAS,RPS6KA1,RAC1,PRKAR1B,CREB1,MAPK14,MAPK1,HRAS,CAMK2G,MAPK3 |
| 4.356e-03 | -5.44 | negative regulation of transferase activity | biological process | GO:0051348 | 312 | 65 | 17256 | 2622 |
FGFR1OP,GGNBP2,TSC2,GMFG,NF1,CIB1,AKT1S1,RGS2,LYN,DUSP22,PSEN1,VPS25,PARK7,MAD2L2,RPL11,FBXO5,PTPN2,TFAP4,CDKN2C,RB1,PTEN,FBXO7,SOCS6,DUS2,H2AFY,CDKN1B,PIK3IP1,MVP,SOCS5,CHP1,PLK1,PDPK1,TNFAIP3,NCK1,PRKAR1B,GBA,GMFB,LRP5,DNAJA1,MEN1,SOCS7,PPP2CA,SH3BP5,HHEX,MBIP,PPP2R5A,GPS2,DUSP3,CSK,PRDX3,CORO1C,LIMK1,STK38,QARS,GADD45B,SOCS4,NUP62,DVL1,NR2F2,NIPSNAP2,POT1,HIPK3,TERF1,PDCD4,CDKN2A |
| 4.357e-03 | -5.44 | HUTTMANN_B_CLL_POOR_SURVIVAL_UP | MSigDB lists | HUTTMANN_B_CLL_POOR_SURVIVAL_UP | 252 | 54 | 17377 | 2626 |
PLXNC1,DCAF15,PRKCSH,XAB2,DNAJB2,COPE,ARID5A,TKT,ACAP1,MAN2B1,MYO9B,NCKAP1,DPYSL2,ARHGEF1,RRBP1,DNM2,FAM89B,GM2A,SLC25A1,CDC37,CLPTM1,ERCC1,PTPN18,RHOBTB3,KLF10,SEPT9,PBXIP1,PRRC2A,BTG2,MAN1B1,LDB1,RFXANK,MEF2D,OGDH,THNSL1,OGFR,COMMD4,PDE3B,RHOT2,SF3A2,RHOB,DAPK3,NEU1,PON2,NUCB1,HGS,GALNT2,NAGLU,SH3GLB2,OGT,ATP6V0C,CABIN1,SNRNP70,CBX4 |
| 4.359e-03 | -5.44 | LGALS3BP (galectin 3 binding protein) | protein interactions | 3959 | 159 | 39 | 17029 | 2761 |
MZT1,PHB2,TWNK,DYNLL1,RAE1,GNE,MOGS,CUL1,NKRF,TUBGCP2,MZT2A,SHC1,PPME1,MVP,ZC3H3,CCT2,TRAPPC9,MIOS,TUBGCP5,CUL3,RPL38,BRCA1,MCM2,FXR1,CCT8,CAND1,MAGED2,SYNCRIP,SURF4,POLE,CEP55,ITGB1,H2AFX,VCPIP1,ACTB,PRPF4,MZT2B,TUBB,N4BP2L2 |
| 4.362e-03 | -5.43 | eye-uveal_tract-malignant_melanoma | COSMIC cancer mutations | eye-uveal_tract-malignant_melanoma | 151 | 35 | 17385 | 2587 |
RECQL,REPS2,NF1,SF3B1,CHIC2,PXMP2,CLCC1,MAN2B1,MYEF2,GTF2F1,FGFR3,RB1,NOL11,PTEN,MSH2,NOC2L,PTPN11,MSH6,EEF1D,NRAS,LAP3,VHL,KRAS,BRCA1,MEN1,KMT2C,PSMB9,GNAS,UBTF,POLE,RBMX,STK11,HRAS,SMAD4,CDKN2A |
| 4.391e-03 | -5.43 | PlsC | smart domains | SM00563 | 16 | 7 | 9493 | 1367 |
AGPAT3,AGPAT2,LPCAT1,TAZ,LCLAT1,LPCAT4,AGPAT1 |
| 4.396e-03 | -5.43 | ACATTCC,MIR-1,MIR-206 | MSigDB lists | ACATTCC,MIR-1,MIR-206 | 280 | 59 | 17377 | 2626 |
PPIB,SMAP1,DNAJC5,UBN1,ARID2,TKT,STARD7,KLF13,SMARCA4,CREBL2,ADPGK,UBE4A,IP6K2,ETS1,KTN1,WDR48,CREM,PHC2,C1GALT1,PDCD10,MEX3C,CDC42,RRBP1,SLC44A1,TNPO2,TRA2B,JOSD1,ATG13,TAGLN2,CITED2,ZNF800,ELOF1,CLCN3,HMGN1,SNX2,TSPYL4,LRRC8A,SLC25A22,MAP4K3,PBRM1,MATR3,PICALM,DHX15,BSDC1,PHF6,SRSF1,DDX17,KIF2A,VEZF1,CORO1C,RNF38,OGT,KHSRP,DDX5,YWHAZ,SRSF3,PDLIM5,ZMAT3,ZNF146 |
| 4.402e-03 | -5.43 | Global Genome Nucleotide Excision Repair (GG-NER) | REACTOME pathways | R-HSA-5696399 | 85 | 24 | 10287 | 1696 |
COPS8,ERCC1,RFC3,RBX1,POLK,SUMO2,CHD1L,INO80E,UBE2I,RFC2,RPA1,RAD23A,RPA2,PCNA,POLE,RPS27A,RAD23B,XPA,ACTB,COPS7B,COPS6,YY1,GTF2H2,DDB1 |
| 4.406e-03 | -5.42 | PHONG_TNF_RESPONSE_VIA_P38_COMPLETE | MSigDB lists | PHONG_TNF_RESPONSE_VIA_P38_COMPLETE | 219 | 48 | 17377 | 2626 |
GOLPH3L,CKLF,AGRN,PPP1R12A,UBR2,TMEM97,B4GALT1,SIKE1,WRB,RGS1,MBD4,FBRS,DLG5,CD59,FANCL,PCNA,NUP210,SHC1,KDM2A,SYNM,AFF1,NCOA2,PTPRK,ADAM17,KLF10,SNX2,NUDT4,ACSL3,MAP4K4,GTPBP4,HTATIP2,MAP7D1,MCL1,NFATC2IP,RAB22A,SH3BP5,HHEX,MAGT1,ETS2,ACOX1,U2SURP,CAPN7,GLG1,PITPNA,STK11,SMURF1,CDK2,CBX4 |
| 4.409e-03 | -5.42 | N-glycan processing | biological process | GO:0006491 | 19 | 8 | 17256 | 2622 |
MAN2A2,PRKCSH,MAN1B1,FUT8,USF3,ST8SIA2,EDEM2,MAN1A1 |
| 4.409e-03 | -5.42 | mitochondrial ATP synthesis coupled proton transport | biological process | GO:0042776 | 19 | 8 | 17256 | 2622 |
COX5B,ATP5MC3,ATP5F1B,CYC1,ATP5F1A,ATP5MF,ATP5PF,STOML2 |
| 4.409e-03 | -5.42 | protein localization to chromatin | biological process | GO:0071168 | 19 | 8 | 17256 | 2622 |
PLK1,LEMD2,H2AFY,MRNIP,RUVBL2,CHMP7,SGF29,CARM1 |
| 4.410e-03 | -5.42 | GO_GUANYL_NUCLEOTIDE_BINDING | MSigDB lists | GO_GUANYL_NUCLEOTIDE_BINDING | 365 | 74 | 17377 | 2626 |
RHOG,RAB14,SUCLG1,RAB11B,RAC1,TPX2,OLA1,RRAGC,GLUD1,RAB21,RAB8A,RAP1A,CDC42,SAR1A,RALB,RAB35,RAB4A,DNM2,UPRT,SUCLG2,SEPT11,RP2,EIF5,ARL5A,NRAS,SEPT9,RAB7A,RAB1A,RAB5B,ARL5B,LSG1,RAB22A,RAB2B,ARF4,RHEB,SEPT1,RAB24,TUBB,RHEBL1,ANXA6,RHOC,GSPT2,RAB23,ARFIP2,ARF1,RAB6A,IFT27,RAB11A,GFM2,RTKN,GTPBP3,ARF5,EFTUD2,DAPK1,GNAI2,RHOA,NOA1,GTPBP4,TUFM,SEPT8,KRAS,RIT1,SEPT7,RHOT1,RHOT2,GUF1,RHOB,MFN2,ADSS,GNAS,GNA12,RAB18,EHD4,HRAS |
| 4.419e-03 | -5.42 | SASS6 (SAS-6 centriolar assembly protein) | protein interactions | 163786 | 77 | 22 | 17029 | 2761 |
FGFR1OP,SCOC,CCDC138,RAE1,HAUS4,EFL1,PCGF1,ERC1,HAUS2,HAUS8,ABRACL,DLG5,KEAP1,PCM1,CCP110,CENPJ,GPATCH1,PRPF4,C2CD5,MTPN,DVL2,ZC3HC1 |
| 4.419e-03 | -5.42 | PPP1R12A (protein phosphatase 1 regulatory subunit 12A) | protein interactions | 4659 | 77 | 22 | 17029 | 2761 |
RHOA,ACTR3,NSUN2,MYH9,CUL1,NUSAP1,CAPZA2,ANLN,RPA1,RPA2,PFDN5,TRIM47,HDAC7,TPP2,TULP3,MYO18A,SIAH2,ROCK1,TTLL12,CDK2,ARRB2,RPRD1B |
| 4.421e-03 | -5.42 | XRN1 (5'-3' exoribonuclease 1) | protein interactions | 54464 | 110 | 29 | 17029 | 2761 |
B3GALT6,EXOSC6,DDX24,POC1A,LDHA,QSOX2,RBM4,PABPC4,GLMP,RPA1,RPA2,SDHB,PPP2CA,C1GALT1,CEP104,PCM1,UPF1,SYNCRIP,CENPJ,RBMX,EXOSC1,DCP1A,NDUFB9,TARDBP,UPF2,CENPBD1,PRADC1,PSMC1,IFI16 |
| 4.421e-03 | -5.42 | BIOCARTA_CELLCYCLE_PATHWAY | MSigDB lists | BIOCARTA_CELLCYCLE_PATHWAY | 23 | 9 | 17377 | 2626 |
CDKN2C,RB1,RBL1,TFDP1,E2F1,CDKN1B,CCNB1,CDK2,CDKN2A |
| 4.421e-03 | -5.42 | GO_RIBOSOMAL_LARGE_SUBUNIT_ASSEMBLY | MSigDB lists | GO_RIBOSOMAL_LARGE_SUBUNIT_ASSEMBLY | 23 | 9 | 17377 | 2626 |
PPAN,DDX28,RPL6,RPL38,RPF2,BRIX1,MRPL11,RPL11,RPL23A |
| 4.421e-03 | -5.42 | GO_SPINDLE_CHECKPOINT | MSigDB lists | GO_SPINDLE_CHECKPOINT | 23 | 9 | 17377 | 2626 |
PLK1,ZNF207,BIRC5,TAOK1,CENPF,CSNK2A1,AURKB,TERF1,MAD2L2 |
| 4.421e-03 | -5.42 | WALLACE_JAK2_TARGETS_UP | MSigDB lists | WALLACE_JAK2_TARGETS_UP | 23 | 9 | 17377 | 2626 |
POLE,POLR2J,UBXN1,TFDP1,TMEM109,MRPL12,KIF22,CDC25B,SRRT |
| 4.421e-03 | -5.42 | REACTOME_INSULIN_RECEPTOR_RECYCLING | MSigDB lists | REACTOME_INSULIN_RECEPTOR_RECYCLING | 23 | 9 | 17377 | 2626 |
ATP6V0B,ATP6V1D,ATP6V0A2,ATP6V0C,ATP6V1B2,ATP6V1C1,ATP6V0E1,ATP6V0D1,ATP6V1G1 |
| 4.434e-03 | -5.42 | Dual Incision in GG-NER | REACTOME pathways | R-HSA-5696400 | 41 | 14 | 10287 | 1696 |
RPA2,ERCC1,PCNA,RFC3,POLE,RBX1,POLK,RPS27A,CHD1L,XPA,RFC2,GTF2H2,DDB1,RPA1 |
| 4.440e-03 | -5.42 | lymphoplasmacytic_lymphoma | COSMIC cancer mutations | lymphoplasmacytic_lymphoma | 12 | 6 | 17385 | 2587 |
KRAS,ARID1A,NRAS,PTEN,HRAS,CDKN2A |
| 4.440e-03 | -5.42 | GH-PRL | COSMIC cancer mutations | GH-PRL | 12 | 6 | 17385 | 2587 |
GNAS,CDKN2C,RB1,MEN1,AXIN1,CDKN2A |
| 4.440e-03 | -5.42 | ovary-low_malignant_potential_(borderline)_tumour | COSMIC cancer mutations | ovary-low_malignant_potential_(borderline)_tumour | 12 | 6 | 17385 | 2587 |
KRAS,NRAS,JAK1,PTEN,SF3B1,CDKN2A |
| 4.440e-03 | -5.42 | pituitary-adenoma-GH-PRL | COSMIC cancer mutations | pituitary-adenoma-GH-PRL | 12 | 6 | 17385 | 2587 |
GNAS,CDKN2C,RB1,MEN1,AXIN1,CDKN2A |
| 4.443e-03 | -5.42 | GSE1460_DP_THYMOCYTE_VS_THYMIC_STROMAL_CELL_DN | MSigDB lists | GSE1460_DP_THYMOCYTE_VS_THYMIC_STROMAL_CELL_DN | 181 | 41 | 17377 | 2626 |
FEZ2,ST13,TMEM184B,WDYHV1,RAC1,ASAH1,B4GALT1,LACTB2,GNB2,MYEF2,PARK7,LMNA,SLC31A1,ZCCHC2,RRBP1,ATP13A3,CNN2,IFT46,MTX2,FAM171A1,TMX1,MYO5A,RHOBTB3,POLR2L,CREG1,ZMYND11,ATXN1,RPL27A,MACF1,SERP1,YIF1A,TMEM184C,NEK1,UEVLD,GOLGA8A,STAT1,IMPDH1,CHPF2,CHPT1,SMNDC1,USP13 |
| 4.443e-03 | -5.42 | GSE41176_UNSTIM_VS_ANTI_IGM_STIM_TAK1_KO_BCELL_6H_UP | MSigDB lists | GSE41176_UNSTIM_VS_ANTI_IGM_STIM_TAK1_KO_BCELL_6H_UP | 181 | 41 | 17377 | 2626 |
MIF,FAM207A,WDYHV1,WDR13,MECP2,CDK2AP2,POFUT1,MAD2L2,CYHR1,IRF4,PDCD10,INTS12,NDUFS8,CRY2,TECR,ERI3,TFG,GTF2H2,FAM3A,ABI1,WDR41,CPNE1,DCAF6,TMEM39A,KAT7,TSPAN31,CYP20A1,DIDO1,SOCS7,AMZ2,MKNK1,CCDC14,RAB24,SNAP29,KBTBD7,SOCS4,TSPAN5,HIPK3,ALS2,SSSCA1,POLQ |
| 4.443e-03 | -5.42 | GSE40666_UNTREATED_VS_IFNA_STIM_EFFECTOR_CD8_TCELL_90MIN_DN | MSigDB lists | GSE40666_UNTREATED_VS_IFNA_STIM_EFFECTOR_CD8_TCELL_90MIN_DN | 181 | 41 | 17377 | 2626 |
RAB14,IER2,TP53RK,GOLIM4,GMFG,CASP6,SRSF6,MAGED1,EIF3D,CUTA,VPS45,JMJD6,COMMD5,SLC12A9,ABHD16A,EFTUD2,CORO1A,FAM76B,PRADC1,TOP1MT,SPTSSA,GPD1L,STRAP,IMPA2,PDLIM2,SNX8,ERCC1,CLCN3,ADAM17,POLR2L,NARF,EXOSC9,ARHGDIB,DCUN1D5,EIF2A,FOXRED1,DTWD1,RBL1,ZNF367,COX8A,UQCRH |
| 4.443e-03 | -5.42 | GSE29618_PRE_VS_DAY7_POST_LAIV_FLU_VACCINE_MONOCYTE_DN | MSigDB lists | GSE29618_PRE_VS_DAY7_POST_LAIV_FLU_VACCINE_MONOCYTE_DN | 181 | 41 | 17377 | 2626 |
MMACHC,IER2,CMAS,C1orf112,RPL15,SECISBP2,GTF3A,ATP6V1B2,EPM2A,WWP2,PTEN,DNAAF2,GPATCH1,TRA2B,ZNF226,CDC25B,GEMIN4,EIF5,ABHD2,ZFP64,ATP13A1,RAB7A,BTG2,ATXN1,SEPT8,PRPSAP1,SLC25A5,ZFAND5,RBM25,PFDN4,DHX16,RPS27A,OSBPL8,CAB39,KPNA2,FKBP5,TAF12,PREPL,PDLIM5,GPATCH4,ZNF146 |
| 4.443e-03 | -5.42 | GSE11961_MARGINAL_ZONE_BCELL_VS_MEMORY_BCELL_DAY40_DN | MSigDB lists | GSE11961_MARGINAL_ZONE_BCELL_VS_MEMORY_BCELL_DAY40_DN | 181 | 41 | 17377 | 2626 |
SLC12A7,TBC1D12,PPP1R37,PRKAB1,HJURP,C1orf112,POC1A,DAP,PMS2,TMEM97,AGPAT3,EBNA1BP2,PMF1,COMMD5,RLF,ETS1,DNAAF2,CNPY4,SEPT11,DDX31,GLE1,TACC3,TELO2,SGCE,MLEC,ZNF512,MKI67,PDE3B,SLTM,ANKRD46,NUCB1,TMEM41A,HINT1,DDOST,DHX16,TATDN2,EIF2D,ACLY,SMPD4,ZNF598,SSRP1 |
| 4.443e-03 | -5.42 | GSE17721_CTRL_VS_LPS_0.5H_BMDC_UP | MSigDB lists | GSE17721_CTRL_VS_LPS_0.5H_BMDC_UP | 181 | 41 | 17377 | 2626 |
KIF3B,DDX47,MAX,ADD1,KIAA0100,MRPL42,CENPF,B4GALT1,BLM,BCAP31,FANCI,CLUAP1,MCM5,GRSF1,BANF1,CAMK2G,KDELR1,MOB4,ETV3,GABPA,LAP3,EMP3,GALK2,ANLN,MARK2,ERC1,ANKRD46,ISG15,ARF4,MFN2,DERL1,JAK1,BIRC5,LUC7L3,COX7A2L,APPL2,MRFAP1L1,CPEB2,EYA2,HDAC2,ALS2 |
| 4.443e-03 | -5.42 | GSE8921_3H_VS_24H_TLR1_2_STIM_MONOCYTE_DN | MSigDB lists | GSE8921_3H_VS_24H_TLR1_2_STIM_MONOCYTE_DN | 181 | 41 | 17377 | 2626 |
MIF,CCNC,GALK1,SART1,PDCD6IP,GPBP1L1,PPP1R15B,DCTN2,SLC2A1,TRIO,KLF13,BZW2,MXD1,GTF2F1,MCTS1,WWP2,TBC1D14,MBD2,MEA1,TP53BP2,S100A6,NUDC,ATP6V1G1,RBM15B,CYTH1,RBM42,TNFAIP3,LDHA,RFFL,MIER2,PICALM,MAP2K2,GPR137,CCDC86,PFDN4,PSMD3,E2F4,TATDN2,PRDX5,GPI,NUDT3 |
| 4.443e-03 | -5.42 | GSE43955_10H_VS_60H_ACT_CD4_TCELL_DN | MSigDB lists | GSE43955_10H_VS_60H_ACT_CD4_TCELL_DN | 181 | 41 | 17377 | 2626 |
CYTIP,DNMT3A,GMFG,NF1,HLA-E,TOR3A,ANKH,PTTG1,COPE,TOP2B,GLUD1,ADPGK,CSNK1A1,CFLAR,ANKRD28,IRF4,EIF2S2,TNFAIP8,PHTF1,MRPL54,KIF22,CNOT6L,S100A6,MYO5A,PPP3CA,WDR82,ZFAND5,KDM3A,NMT2,ANKZF1,AHNAK,HNRNPR,PRDX5,GLG1,BCL7C,MPV17,RNF38,SLC16A1,TRAF5,PURA,TSEN15 |
| 4.443e-03 | -5.42 | GSE36888_STAT5_AB_KNOCKIN_VS_WT_TCELL_IL2_TREATED_6H_UP | MSigDB lists | GSE36888_STAT5_AB_KNOCKIN_VS_WT_TCELL_IL2_TREATED_6H_UP | 181 | 41 | 17377 | 2626 |
DDX58,SEPHS2,CXXC1,TM9SF3,AGPAT3,MYO9B,GYG1,LYRM2,IL21R,ASXL2,COPG2,HMG20A,USP5,C2orf68,MTMR4,RCSD1,TALDO1,ACP2,PSPC1,HELB,CUL3,SEPT7,COMMD4,STK17B,POLR2A,ISG15,RHOB,DAP3,SGSH,HGS,ACYP1,WDR59,NLRC5,QRSL1,PITPNA,RBBP4,CLN3,BEND6,HEXA,RNF139,FAF1 |
| 4.462e-03 | -5.41 | Ypel5 (yippee like 5) | protein interactions | 383295 | 18 | 8 | 17029 | 2761 |
GID8,RMND5A,NUP188,MKLN1,MAGT1,LETMD1,ARMC8,HEXA |
| 4.462e-03 | -5.41 | Bap1 (Brca1 associated protein 1) | protein interactions | 104416 | 18 | 8 | 17029 | 2761 |
COG1,BRCA1,KDM1B,FOXK1,ASXL2,CENPJ,DDX42,DNAAF5 |
| 4.462e-03 | -5.41 | ZNF420 (zinc finger protein 420) | protein interactions | 147923 | 18 | 8 | 17029 | 2761 |
MDM2,CDC42,UBE2I,RBM4,SENP1,TRIM28,CDKN2A,H2AFX |
| 4.462e-03 | -5.41 | BRINP3 (BMP/retinoic acid inducible neural specific 3) | protein interactions | 339479 | 18 | 8 | 17029 | 2761 |
HGS,KIAA0232,CBWD1,ATG2B,LRP5,DHFR2,EDEM2,DNAJB9 |
| 4.462e-03 | -5.41 | NEIL3 (nei like DNA glycosylase 3) | protein interactions | 55247 | 18 | 8 | 17029 | 2761 |
SMARCA4,CDKN2AIP,ROCK1,RBM25,SLC2A1,GPATCH4,SF3B2,BCL7C |
| 4.462e-03 | -5.41 | BCORL1 (BCL6 corepressor like 1) | protein interactions | 63035 | 18 | 8 | 17029 | 2761 |
USP7,KRAS,EWSR1,FBL,PCGF1,HDAC7,PCGF6,RYBP |
| 4.462e-03 | -5.41 | TMEM258 (transmembrane protein 258) | protein interactions | 746 | 18 | 8 | 17029 | 2761 |
RPN1,RPN2,MLEC,DDOST,MAGT1,STT3A,DAD1,FUT8 |
| 4.462e-03 | -5.41 | FOXJ3 (forkhead box J3) | protein interactions | 22887 | 18 | 8 | 17029 | 2761 |
RPA2,ZBTB10,UBR2,RANGAP1,USP11,TERF1,DDX42,TERF2 |
| 4.467e-03 | -5.41 | GSE4590_PRE_BCELL_VS_VPREB_POS_LARGE_PRE_BCELL_DN | MSigDB lists | GSE4590_PRE_BCELL_VS_VPREB_POS_LARGE_PRE_BCELL_DN | 149 | 35 | 17377 | 2626 |
CLSPN,NOP2,UBR2,SHPRH,ADO,GNE,ACAP1,EIF2AK4,EIF1B,SNAPC4,PAIP1,SLC25A36,CDC42,ATP13A3,DAPK1,ANXA5,METTL9,CNNM3,RNF169,TERF2,PPAN,FYTTD1,B3GALT6,RPRD1A,NXT1,FAM118B,NARF,RBM38,PPP3R1,SAMD8,SSNA1,SNRNP70,ATP6V0E1,USP53,FUBP1 |
| 4.475e-03 | -5.41 | Inhibition of TSC complex formation by PKB | REACTOME pathways | R-HSA-165181 | 3 | 3 | 10287 | 1696 |
TSC1,TSC2,AKT2 |
| 4.492e-03 | -5.41 | GSE11057_NAIVE_CD4_VS_PBMC_CD4_TCELL_UP | MSigDB lists | GSE11057_NAIVE_CD4_VS_PBMC_CD4_TCELL_UP | 165 | 38 | 17377 | 2626 |
ZNF76,NSMCE4A,UBXN1,SLC39A13,ARFIP2,DNAJB1,PITHD1,ZNF275,PCYOX1L,CYHR1,ZNF420,NOL11,IL6ST,AXIN2,RPL19,PIK3IP1,CNOT6L,ZRANB1,CPSF4,CAMK2G,ZNF189,NIPAL3,PHF10,TSPYL4,NET1,TBRG4,ADSL,DIDO1,ZNF407,ZNF862,UPF1,CHD3,MAFK,EIF2D,USP20,PITRM1,PPP2R2D,IPO4 |
| 4.492e-03 | -5.41 | GO_CYTOPLASMIC_SIDE_OF_MEMBRANE | MSigDB lists | GO_CYTOPLASMIC_SIDE_OF_MEMBRANE | 165 | 38 | 17377 | 2626 |
PKP4,CYLD,NF1,RACGAP1,RGS2,LYN,MIEN1,BIRC2,RGS1,SPPL2A,ABL2,RAB21,ATP2A2,PTEN,SNX18,GNAI2,HTRA2,GM2A,KCNAB2,S100A6,CYTH1,RHOA,GNG7,EZR,KRAS,DNAJA1,SPPL2B,MAP2K2,GNAS,GNA12,CHMP4A,JAK1,CSK,PTPN7,CHMP4B,PKD2,TRAF5,ESYT2 |
| 4.492e-03 | -5.41 | GO_CHROMATIN_ASSEMBLY_OR_DISASSEMBLY | MSigDB lists | GO_CHROMATIN_ASSEMBLY_OR_DISASSEMBLY | 165 | 38 | 17377 | 2626 |
HJURP,UBN1,ARID2,SHPRH,CTCF,SMARCA4,OIP5,SUV39H2,NOC2L,H2AFY,CENPM,NAP1L4,SMARCE1,TNRC18,HP1BP3,NASP,TSPYL4,MTA2,ARID1A,MCM2,ASF1B,SUPT16H,CHAF1A,PAF1,NAP1L1,BRD2,CHD3,H2AFX,BAZ1B,CABIN1,HMGB2,CENPT,RBBP4,H3F3A,NAA60,IPO4,CDKN2A,SMARCD1 |
| 4.492e-03 | -5.41 | MODULE_52 | MSigDB lists | MODULE_52 | 417 | 83 | 17377 | 2626 |
TMEM106C,NQO1,FOXM1,PTTG1,SLC2A1,UCK2,TPX2,C5orf30,CSNK2A1,PTP4A3,GYG1,CCNB1,STMN1,BIRC2,SSR1,KIFC1,CDKN2C,SEC11A,PCNA,CCNA2,AP1M1,DNM2,CDC25B,RNASEH2A,OGG1,HTRA2,PRPF19,PLK1,SGCE,TIMP2,E2F3,RRM2,PKMYT1,SOX4,CCNF,MCM2,PRPSAP1,CHAF1A,DPYSL3,DDX17,PON2,TRAM2,H2AFX,ADAM9,RPS26,MAPRE1,SRGN,CENPF,UBXN1,RRM1,ARFIP2,TMED3,ITGB5,RAB11A,WRB,TFRC,NUP205,FGFR3,GART,PPP4R1,GTSE1,CITED2,TMX1,MSH6,STAU1,ACSL3,MYBL2,ILF3,EMP3,ADSL,PLEC,ARID1A,KIF11,CYB5A,ISG15,SYNCRIP,E2F1,CDK2,CCNB2,UBE2C,ESPL1,IFI16,CDKN2A |
| 4.509e-03 | -5.40 | TCANNTGAY_V$SREBP1_01 | MSigDB lists | TCANNTGAY_V$SREBP1_01 | 446 | 88 | 17377 | 2626 |
ZNF207,RORB,PPCS,PDCD6IP,YTHDF3,RRAGC,ATP6V1B2,DAZAP2,ZADH2,GNB2,GIT2,APP,KDM2A,ATG3,CS,TNPO2,JOSD1,TMEM136,AHCYL1,ATF2,DVL2,CGGBP1,MOSPD1,KDM3B,PPT1,KAT7,TOPORS,UBE2V1,CHMP2B,RAB5B,TOLLIP,RAB22A,SUPT16H,C19orf54,PWWP2B,STT3A,HPS5,ZNF367,NSMCE2,MRPL27,ATP6V0C,CLN3,SMNDC1,STARD3NL,ATXN7L2,EYA1,MANBA,ADO,CTCF,BLM,ASXL2,RAPGEF6,RGS1,TFAP4,CTSS,ARPC5,ZDHHC13,H2AFY,PCYT2,CITED2,ATP6V0D1,ACP2,ETV3,SNX2,ILF3,TOP3A,ARHGEF12,UBE4B,PICALM,SNRPA,PTPRF,ATP6V1D,PCM1,SLC38A7,DUSP3,ASNA1,CTSA,MBD6,PSAP,RGL1,ATP6V1C1,RBBP4,RUFY3,CDK2,RNF14,HEXA,PURA,ALS2 |
| 4.510e-03 | -5.40 | FERMT2 (fermitin family member 2) | protein interactions | 10979 | 59 | 18 | 17029 | 2761 |
SEPT9,NADK2,CNTROB,APP,PICALM,BBS12,MAPK3,FERMT3,MAT2B,PDCD10,GRK2,CENPJ,NAA50,SEPT11,YWHAZ,EIF5,YWHAH,MAPK1 |
| 4.510e-03 | -5.40 | DMWD (DM1 locus, WD repeat containing) | protein interactions | 1762 | 59 | 18 | 17029 | 2761 |
SRM,GALK1,NDUFA5,DCAF15,IDH3A,TKT,CUL3,NUP155,OAT,RAB2B,WDR48,ALDH3B1,FTSJ1,SUCLG2,FEM1B,YWHAH,PFKP,CDC37 |
| 4.510e-03 | -5.40 | PLPBP (pyridoxal phosphate binding protein) | protein interactions | 11212 | 59 | 18 | 17029 | 2761 |
PPP1R2,UBXN1,HEXB,TUFM,ENSA,MCM2,TWF2,MYEF2,RPA1,PAPOLA,MCTS1,DDX17,CAPN2,GRK2,ATIC,AHSA1,TATDN1,ASB6 |
| 4.526e-03 | -5.40 | REACTOME_TRANSCRIPTION | MSigDB lists | REACTOME_TRANSCRIPTION | 192 | 43 | 17377 | 2626 |
CTDP1,CDC40,H2AFZ,POLR2K,SRSF6,RBM8A,SNRPD3,SNAPC4,POLR3K,PAPOLA,GTF2F1,RRN3,ZNF473,MBD2,SRSF4,TCEA1,POLR1B,GTF2H2,CSTF1,SRSF11,POLR2I,POLR2G,POLR2L,SNRPB,POLR2D,RNPS1,SLBP,POLR3GL,SRSF5,POLR2A,MAPK3,SRSF1,SUPT16H,CBX3,UBTF,POLR2J,H2AFX,TAF12,SRSF3,SNRPG,H3F3A,TAF6,SSRP1 |
| 4.526e-03 | -5.40 | GOLDRATH_EFF_VS_MEMORY_CD8_TCELL_DN | MSigDB lists | GOLDRATH_EFF_VS_MEMORY_CD8_TCELL_DN | 192 | 43 | 17377 | 2626 |
SLC12A7,ASH1L,WDR13,MECP2,EZH1,CCNL2,EIF2AK4,NCKAP1,CRLF3,METTL3,FAM8A1,ABHD14A,UBLCP1,RTKN,GSTK1,SIAH1,IL6ST,RPL19,TTC3,BCL2,SLC26A2,POLR1B,ABCC5,ADCY7,B3GALT6,EMB,MFNG,MAP4K3,NDUFA7,VKORC1,SLTM,XRCC5,ANKRD10,SH3BP5,PDRG1,COX7A2L,RPLP1,MLYCD,CANT1,ZFP90,ACADM,TRAF5,PURA |
| 4.526e-03 | -5.40 | KAECH_DAY15_EFF_VS_MEMORY_CD8_TCELL_DN | MSigDB lists | KAECH_DAY15_EFF_VS_MEMORY_CD8_TCELL_DN | 192 | 43 | 17377 | 2626 |
SLC12A7,GALK1,KARS,DNAJB2,MCCC1,MOGS,PCBP1,ABHD14A,RBM17,GSTK1,GART,HDAC7,BANF1,ANXA5,BCL2,FBL,F2R,FTL,ELOVL5,ATP13A1,TSPAN31,PPIE,LDHA,GLO1,VKORC1,KLF6,PSMB9,LUC7L,GOSR1,RPSA,HSPA1B,SCARB2,STX18,RNF38,GALNT10,MAP3K5,SMAD1,IGBP1,HEXA,TOB1,EYA2,TUBB,NUDT3 |
| 4.526e-03 | -5.40 | GSE35685_CD34POS_CD38NEG_VS_CD34POS_CD10POS_BONE_MARROW_DN | MSigDB lists | GSE35685_CD34POS_CD38NEG_VS_CD34POS_CD10POS_BONE_MARROW_DN | 192 | 43 | 17377 | 2626 |
SLC12A7,GCLM,CASP6,SLC41A1,TOR3A,GADD45G,SLC2A1,TAP1,PMS2,NUP54,C5orf30,AGFG1,LYN,STAM,BZW2,CAPN2,VMP1,TBC1D14,RRBP1,BUD31,TPST1,AFF1,CLDND1,SGCB,TIPARP,STAT3,TRAFD1,DDX24,FAM49B,TOR1AIP2,EDF1,ZFAND5,PSMB9,ISG15,JAK1,DCK,PML,ADAM9,ATF6,CHMP4B,B4GALT3,RAB3IL1,PFKP |
| 4.529e-03 | -5.40 | ZNF263 (zinc finger protein 263) | protein interactions | 10127 | 68 | 20 | 17029 | 2761 |
TRIM41,FTL,ZNF445,PPP1R12A,TRAF7,KLHL21,TWNK,TOPORS,THNSL1,PLEKHF2,RAD18,LTBP4,RPS27A,MTMR4,CLK3,PPM1G,AHCYL1,ANKHD1,PPP2R2D,DVL2 |
| 4.529e-03 | -5.40 | DUSP9 (dual specificity phosphatase 9) | protein interactions | 1852 | 68 | 20 | 17029 | 2761 |
SRM,TMUB1,PRIM2,MBLAC2,TMEM97,GLRX3,MAPK14,RAB5B,SDHA,PARK7,MAPK3,PRIM1,PFDN5,RAP1A,PFDN4,ARF5,PGRMC1,LTN1,MAPK1,HRAS |
| 4.529e-03 | -5.40 | PTAR1 (protein prenyltransferase alpha subunit repeat containing 1) | protein interactions | 375743 | 68 | 20 | 17029 | 2761 |
UBE2D3,TRAPPC13,BRD4,JTB,ARMH3,RAB1A,GOSR1,TMEM165,RIC1,RAB18,SEC23IP,CMTR2,SNAP23,EXOSC1,EXOC4,SPTSSA,PIKFYVE,TMED2,NXT2,TMEM131 |
| 4.529e-03 | -5.40 | TIAL1 (TIA1 cytotoxic granule associated RNA binding protein like 1) | protein interactions | 7073 | 68 | 20 | 17029 | 2761 |
SARNP,SCAMP3,CUL3,CUL1,BRCA1,TOMM40,VDAC1,PCGF1,PCBP1,MAPK3,RPA1,CAND1,KIF2A,RPA2,DUT,KBTBD7,SRI,COPS6,MAPK1,PCBP2 |
| 4.529e-03 | -5.40 | AKT2 (AKT serine/threonine kinase 2) | protein interactions | 208 | 68 | 20 | 17029 | 2761 |
PDPK1,SNX27,NSMCE4A,GGA1,PRKDC,VHL,AKT2,RACGAP1,AKT1S1,PSMD9,APPL1,APP,POFUT1,PPP2CA,CSK,TTC3,POLR1B,NR2F2,TMED2,EGLN1 |
| 4.535e-03 | -5.40 | GO_ATPASE_COUPLED_ION_TRANSMEMBRANE_TRANSPORTER_ACTIVITY | MSigDB lists | GO_ATPASE_COUPLED_ION_TRANSMEMBRANE_TRANSPORTER_ACTIVITY | 63 | 18 | 17377 | 2626 |
ATP13A1,ABCC10,ATP2C1,ATP6V0A1,ATP6V1B2,ATP6V0B,ATP1A1,ATP2A2,ATP13A3,ATP6V0A2,ANXA5,ATP6V0C,ATP6V1C1,ATP6V0E1,ATP6V0D1,ABCC1,ABCC5,ATP6V1G1 |
| 4.537e-03 | -5.40 | human chr10p15.2 | chromosome location | human chr10p15.2 | 4 | 3 | 26185 | 2809 |
KLF6,PITRM1,PFKP |
| 4.544e-03 | -5.39 | PWWP | smart domains | SM00293 | 20 | 8 | 9493 | 1367 |
PWWP2A,PWWP2B,DNMT3A,BRPF3,ZMYND11,NSD3,HDGFL2,MSH6 |
| 4.546e-03 | -5.39 | GO_GDP_BINDING | MSigDB lists | GO_GDP_BINDING | 49 | 15 | 17377 | 2626 |
RAB21,RAB14,RAB18,RAB8A,RALB,RAB11B,RAB35,RAB7A,RAB4A,RRAGC,KRAS,ARF1,RAB5B,RAB22A,RHOB |
| 4.546e-03 | -5.39 | GCM_PFN1 | MSigDB lists | GCM_PFN1 | 49 | 15 | 17377 | 2626 |
RPL29,H2AFZ,RHOA,PSMD8,DRAP1,ARHGEF1,RPS24,ARHGDIB,RPL19,SNRPD3,CBFB,OAZ1,SNRPA,CFL1,HNRNPM |
| 4.557e-03 | -5.39 | GO_GOLGI_TO_PLASMA_MEMBRANE_TRANSPORT | MSigDB lists | GO_GOLGI_TO_PLASMA_MEMBRANE_TRANSPORT | 40 | 13 | 17377 | 2626 |
CCDC93,GCC2,GOLGA4,SYS1,GOLGA7,NSF,GOPC,ANK3,DNM2,CHIC2,RAB3IP,MACF1,OPTN |
| 4.557e-03 | -5.39 | GO_RNA_SECONDARY_STRUCTURE_UNWINDING | MSigDB lists | GO_RNA_SECONDARY_STRUCTURE_UNWINDING | 40 | 13 | 17377 | 2626 |
DDX28,DDX56,DDX47,DDX24,EIF4A3,DDX20,DDX5,DDX31,DDX39A,DDX52,DDX23,DDX42,DDX17 |
| 4.563e-03 | -5.39 | Activation of ATR in response to replication stress | REACTOME pathways | R-HSA-176187 | 37 | 13 | 10287 | 1696 |
RPA2,RFC3,MCM10,CLSPN,MCM5,DBF4,CDC6,ORC1,MCM2,ORC3,CDK2,RFC2,RPA1 |
| 4.563e-03 | -5.39 | TNF alpha Signaling Pathway | WikiPathways | WP231 | 94 | 25 | 5312 | 837 |
PLK1,NRAS,TXN,TNFAIP3,BIRC3,RAF1,RAC1,RFFL,CUL1,CSNK2A1,KRAS,BCL2L1,BIRC2,FADD,MAPK3,CFLAR,PPP2CA,PSMD2,TAB2,TANK,MAP3K14,MAP3K5,MAPK1,HRAS,CDC37 |
| 4.568e-03 | -5.39 | RB_P130_DN.V1_UP | MSigDB lists | RB_P130_DN.V1_UP | 123 | 30 | 17377 | 2626 |
TK1,POLR2I,OAF,PPP1R15B,SNRPB,NKD2,RACGAP1,SLC29A1,SDF2L1,AURKB,ORC1,B4GALT4,SNN,EIF1B,MBD3,GFER,CHCHD6,ZNF428,C12orf10,HINT1,BIRC5,GLIS2,EFTUD2,KIF22,RUVBL2,CCNB2,UBE2C,RAD51D,ELOF1,USP13 |
| 4.578e-03 | -5.39 | WWE-dom | interpro domains | IPR004170 | 12 | 6 | 18492 | 2768 |
PARP12,TRIP12,TIPARP,HUWE1,ZC3HAV1,DTX4 |
| 4.579e-03 | -5.39 | ATGCTGC,MIR-103,MIR-107 | MSigDB lists | ATGCTGC,MIR-103,MIR-107 | 203 | 45 | 17377 | 2626 |
KIF3B,ZBTB10,NF1,ARID5A,KIF23,GLUD1,AGFG1,DCUN1D4,PDCD10,ZNRF2,MTMR4,ZCCHC2,PPP6C,AXIN2,EIF5,FAM171A1,CFL1,CARM1,RYBP,VOPP1,CSNK1G2,PHF20L1,CELSR2,BAZ2A,C16orf72,BTG2,USP42,MEF2D,CAPZA2,ARMC8,BSDC1,SH3BP5,RAD51C,KPNA1,ZHX1,ZC3H7B,OGT,RNF38,CAB39,PITPNA,PIEZO1,PPP6R2,YWHAH,TSPAN5,DYNC1LI2 |
| 4.586e-03 | -5.38 | polysome | cellular component | GO:0005844 | 74 | 20 | 18223 | 2701 |
UNK,RWDD1,AGO2,RPL6,DHX9,RPL38,RPL8,PSMA1,EIF2AK4,FXR1,EIF4H,RPL36,RPL11,PSMA6,RPL32,RPL19,UPF2,FUS,RPS26,NAA35 |
| 4.590e-03 | -5.38 | cell volume homeostasis | biological process | GO:0006884 | 23 | 9 | 17256 | 2622 |
SLC12A7,CLCN3,ADD1,E2F4,CLCN6,LRRC8A,SLC12A9,SLC12A2,CLNS1A |
| 4.590e-03 | -5.38 | membrane protein ectodomain proteolysis | biological process | GO:0006509 | 23 | 9 | 17256 | 2622 |
ADAM17,ADAM10,APH1A,RBMX,ADAM9,MYH9,PSEN1,SPPL2B,SPPL2A |
| 4.598e-03 | -5.38 | histone acetylation | biological process | GO:0016573 | 102 | 26 | 17256 | 2622 |
KAT2A,KAT7,MECP2,LDB1,ELP4,TAF6L,USP22,WDR5,SUPT7L,MBD3,MEAF6,IRF4,MBIP,BRPF3,TEX30,OGT,NAA50,KANSL2,TAF5L,RUVBL2,NCOA1,BEND3,TAF12,ATF2,NAA60,SGF29 |
| 4.604e-03 | -5.38 | ATP5F1D (ATP synthase F1 subunit delta) | protein interactions | 513 | 46 | 15 | 17029 | 2761 |
DDOST,FAM172A,ATP5MC3,VDAC2,TOP3A,COX5A,COX4I1,ATP5F1B,ATP5F1A,ATP5MF,VDAC1,CDK2,ATP5PF,ATP6V0D1,COPB2 |
| 4.604e-03 | -5.38 | MLLT1 (MLLT1, super elongation complex subunit) | protein interactions | 4298 | 46 | 15 | 17029 | 2761 |
PAF1,BRD4,ELL2,MRPL12,H2AFX,CSNK2A1,AFF1,ARID1A,WDR5,ARRB2,CHD1,PIP4K2A,POLR2A,RYBP,DOT1L |
| 4.604e-03 | -5.38 | RPP38 (ribonuclease P/MRP subunit p38) | protein interactions | 10557 | 46 | 15 | 17029 | 2761 |
RPP25,VASP,PSMA6,ASPM,CAST,POP7,PCGF6,PSMA1,CTR9,CBWD1,TOR1AIP2,CDC23,RBM4,GLMP,CDKN2A |
| 4.604e-03 | -5.38 | MPP1 (membrane palmitoylated protein 1) | protein interactions | 4354 | 46 | 15 | 17029 | 2761 |
TK1,SARNP,CLSPN,MRPS15,STK38,RPS6KA1,PRDX5,MRPS26,AGFG1,ERBIN,METTL3,USP21,HDAC2,PRDX1,OPTN |
| 4.604e-03 | -5.38 | MYH14 (myosin heavy chain 14) | protein interactions | 79784 | 46 | 15 | 17029 | 2761 |
PAF1,SHC1,SUZ12,PIK3R2,ZNF746,SRI,MYH9,CTR9,NUP155,BRCA1,MCM2,CHMP2B,DNMT1,CDC73,ECH1 |
| 4.604e-03 | -5.38 | SAP130 (Sin3A associated protein 130) | protein interactions | 79595 | 46 | 15 | 17029 | 2761 |
TFAP4,MAX,FOXK1,PHF23,VHL,SF3B1,PML,TPX2,CUL1,H3F3A,SINHCAF,MXD1,DDB1,HDAC2,SAP30 |
| 4.604e-03 | -5.38 | PPP1R8 (protein phosphatase 1 regulatory subunit 8) | protein interactions | 5511 | 46 | 15 | 17029 | 2761 |
SNUPN,CTNNBL1,SHC1,SUZ12,SF3B1,RTCB,CSNK2A1,KRAS,RBBP4,PRKACA,LYN,APP,SF3A2,HDAC2,CDC5L |
| 4.604e-03 | -5.38 | NCBP2 (nuclear cap binding protein subunit 2) | protein interactions | 22916 | 46 | 15 | 17029 | 2761 |
KPNA4,UPF1,SYNCRIP,ZCCHC8,UBA5,RBM8A,HNRNPF,CUL1,KPNA2,RBM3,USP48,EIF5,SF3A2,PRPF4B,CAND1 |
| 4.604e-03 | -5.38 | GSPT2 (G1 to S phase transition 2) | protein interactions | 23708 | 46 | 15 | 17029 | 2761 |
YTHDC1,CCT2,UPF1,IDE,NASP,SNX2,CLK3,STAT1,PIP4K2C,ATP6V1C1,PABPC1,APP,PAIP1,PABPC4,SRSF1 |
| 4.607e-03 | -5.38 | TTTTGAG,MIR-373 | MSigDB lists | TTTTGAG,MIR-373 | 214 | 47 | 17377 | 2626 |
USP7,PKP4,YTHDF3,RLF,RAB11A,SCYL2,NPLOC4,CSDE1,RAP1A,WDR44,MTMR4,IMPAD1,EI24,TRA2B,TARDBP,ALDH18A1,SENP1,ARID4A,SEH1L,KDELR1,RLIM,ELOVL5,PHF20L1,PPP3CA,MLEC,GOPC,RNPS1,CAPZA2,SRSF5,SOX4,ARMC8,CBFB,SH3GLB1,ARF4,KRIT1,SERTAD2,KPNA4,GOLGA4,BRD2,SURF4,FBXO28,CSK,SETD3,PTER,SLAIN1,TOB1,SMNDC1 |
| 4.610e-03 | -5.38 | adenoma-nodule-goitre | COSMIC cancer mutations | adenoma-nodule-goitre | 64 | 18 | 17385 | 2587 |
NRAS,VHL,KRAS,MEN1,ERC1,KTN1,GNAS,RB1,FGFR3,PCM1,PTEN,CCDC6,PTPN11,STK11,TFG,HRAS,SMAD4,CDKN2A |
| 4.613e-03 | -5.38 | SHETH_LIVER_CANCER_VS_TXNIP_LOSS_PAM2 | MSigDB lists | SHETH_LIVER_CANCER_VS_TXNIP_LOSS_PAM2 | 144 | 34 | 17377 | 2626 |
NOL12,RPAP3,COX5B,PSRC1,CKLF,RHOC,BTG2,DYNLL1,MAP4K4,PTTG1,CERK,C5orf30,PFKFB3,RRM2,NUF2,NENF,PAWR,MYO9B,EIF2AK4,SOX4,MCM2,TANC1,TWF2,APP,ABHD5,RTKN,GOLM1,DNAJC10,NAP1L1,SLC1A4,STT3A,AKR1B1,TAGLN2,ABCC5 |
| 4.622e-03 | -5.38 | regulation of cyclin-dependent protein kinase activity | biological process | GO:1904029 | 92 | 24 | 17256 | 2622 |
BCCIP,PLK1,CCNC,ADAM17,PSRC1,TNFAIP3,GTPBP4,CDC6,PKMYT1,CCNL2,CCNB1,BLM,MEN1,CCNK,CDKN2C,TFAP4,HHEX,PTEN,FBXO7,CDKN1B,PKD2,NR2F2,CDKN2A,CDC37 |
| 4.623e-03 | -5.38 | GSE27786_LIN_NEG_VS_NEUTROPHIL_UP | MSigDB lists | GSE27786_LIN_NEG_VS_NEUTROPHIL_UP | 176 | 40 | 17377 | 2626 |
NSMCE4A,GNPNAT1,NOP2,RPLP2,C1orf112,SUZ12,ANKH,UCK1,ABCB10,LRRC14,FARSA,MRPL34,POLR1B,LRRC59,FAM171A1,PCBP2,SLC25A1,LDHB,ACSL5,ENPP4,PHF10,SNRNP200,PGGT1B,RAD51AP1,SCFD2,SEPT8,MIER2,FAM133B,DAP3,MAGT1,DHX16,ARNTL,DBI,PML,PTAR1,PIAS2,SMPD4,RBBP4,POT1,ALS2 |
| 4.623e-03 | -5.38 | GSE5542_UNTREATED_VS_IFNA_TREATED_EPITHELIAL_CELLS_6H_UP | MSigDB lists | GSE5542_UNTREATED_VS_IFNA_TREATED_EPITHELIAL_CELLS_6H_UP | 176 | 40 | 17377 | 2626 |
LUZP1,FAM129A,FLOT1,MYO9B,ATP6V1B2,LYAR,IRF4,NEK6,SEC24C,ETV6,LPIN2,TANK,ARL6IP1,JOSD1,CLDND1,MAST2,RNF135,MYBL1,F2R,SMC4,TGFB1,ORAI2,RDH10,CPOX,ATXN1,NFATC2,OGDH,EIF3A,RHBDF2,MYO1F,FAS,PI4K2A,CACNB1,AHNAK,SURF4,ODF2,ITGB1,MBOAT1,LRP8,CAPN1 |
| 4.636e-03 | -5.37 | CLK2 (CDC like kinase 2) | protein interactions | 1196 | 96 | 26 | 17029 | 2761 |
YTHDC1,ZCCHC8,GSPT2,RNPS1,HNRNPF,BCLAF1,GMCL1,BRCA1,THRAP3,UBE2I,LUC7L,SRRT,ZNF473,HUWE1,CLK3,TNPO3,SNRNP70,CPSF4,NKAPD1,PABPC1,LUC7L2,CDKN2A,HNRNPM,SRSF10,PRPF4B,SRPK2 |
| 4.636e-03 | -5.37 | Ppp2r1a (protein phosphatase 2, regulatory subunit A, alpha) | protein interactions | 51792 | 96 | 26 | 17029 | 2761 |
MOB4,ANKLE2,FGFR1OP,STRIP1,FOPNL,DYNLL1,STRN4,GLUD1,PPFIA3,MRPL19,PPP2CA,PCM1,PPP2R5A,INTS7,CCDC6,HPS5,INTS1,PPME1,PPP4R1,STX18,ARHGEF2,INTS12,FAM122A,PKD2,ASNA1,PPP2R2D |
| 4.655e-03 | -5.37 | IL-6 signaling pathway | WikiPathways | WP364 | 43 | 14 | 5312 | 837 |
VAV1,JAK1,SHC1,IL6ST,RAC1,PIK3R2,PTPN11,STAT1,NCOA1,BCL2L1,STAT3,MAPK1,MAP2K2,MAPK3 |
| 4.658e-03 | -5.37 | human chr6p21.31 | chromosome location | human chr6p21.31 | 55 | 13 | 26185 | 2809 |
LEMD2,BAK1,ZNF76,BRPF3,STK38,RPS10,KCTD20,FKBP5,UHRF1BP1,MAPK14,FANCE,NUDT3,DEF6 |
| 4.659e-03 | -5.37 | GSE21360_NAIVE_VS_SECONDARY_MEMORY_CD8_TCELL_DN | MSigDB lists | GSE21360_NAIVE_VS_SECONDARY_MEMORY_CD8_TCELL_DN | 160 | 37 | 17377 | 2626 |
PTMS,CDS2,DNMT3A,PARP12,PLXNC1,KLHL21,RRAGC,COX4I1,PLXNA1,ATP6V1B2,RGS1,TFRC,LMNA,GNS,APLP2,CLIC4,IL6ST,BRI3,CNOT6L,TALDO1,PACS2,S100A6,TRAFD1,MAP4K3,AMDHD2,CHCHD6,DOT1L,MYO1F,PLD3,AHNAK,KEAP1,OSBPL8,LUC7L3,OGT,SAMD8,PDXK,WDR91 |
| 4.659e-03 | -5.37 | GSE7568_IL4_VS_IL4_AND_TGFB_TREATED_MACROPHAGE_24H_UP | MSigDB lists | GSE7568_IL4_VS_IL4_AND_TGFB_TREATED_MACROPHAGE_24H_UP | 160 | 37 | 17377 | 2626 |
SLC12A7,PDCD6IP,PARP12,UBR2,FAM129A,HEXB,EZH1,AP3S1,SYNRG,RAPGEF6,TTF1,GIT2,HMG20A,RNF103,XPR1,CFLAR,GOLM1,CDC42,PTPN11,MOB1A,CYTH1,ERMP1,WBP2,HTATIP2,PDE3B,EIF3H,SMAP2,SCARB2,VPS26B,NSMCE2,ERGIC3,ARNTL,PML,FBXL3,BRWD3,PDLIM5,HEXA |
| 4.659e-03 | -5.37 | cellular response to oxygen levels | biological process | GO:0071453 | 213 | 47 | 17256 | 2622 |
UBE2D3,DNMT3A,PHB2,PRKAA1,SLC29A1,SIRT2,CCNB1,PSMD9,FOXO3,LMNA,EEF2K,CFLAR,PSMD2,CCNA2,PSMA6,MDM2,PSMD1,SUV39H2,TIGAR,PTEN,ATP6V0A2,BCL2,CITED2,ATP6V0D1,HP1BP3,ATP6V1G1,PLK3,RBX1,PSMA8,VHL,ERO1A,PSMB7,PSMA1,PSMB9,PSMB3,PSMC4,FAS,TSC1,RPS27A,PSMD8,PSMD3,HIPK2,E2F1,RBPJ,CPEB2,PSMC1,EGLN1 |
| 4.672e-03 | -5.37 | STI1 | smart domains | SM00727 | 9 | 5 | 9493 | 1367 |
UBQLN4,UBQLN2,ST13,RAD23B,RAD23A |
| 4.672e-03 | -5.37 | UBX | smart domains | SM00166 | 9 | 5 | 9493 | 1367 |
UBXN2A,UBXN2B,UBXN1,FAF1,NSFL1C |
| 4.703e-03 | -5.36 | UNC45A (unc-45 myosin chaperone A) | protein interactions | 55898 | 82 | 23 | 17029 | 2761 |
FGFR1OP,MAX,CYLD,POC1A,UBXN1,MYH9,CAPZA2,WDR5,CSNK1A1,LMNA,EVC2,CCP110,HUWE1,CENPJ,UCHL5,PPME1,ZNF746,XRCC3,CLN3,SASS6,NUP85,CDC37,CDC5L |
| 4.708e-03 | -5.36 | CSAPPISMRASE | prints domains | PR00153 | 22 | 7 | 4652 | 473 |
PPIF,PPIB,PPWD1,CWC27,PPIG,PPIE,PPIL2 |
| 4.713e-03 | -5.36 | GO_POSITIVE_REGULATION_OF_TYPE_I_INTERFERON_PRODUCTION | MSigDB lists | GO_POSITIVE_REGULATION_OF_TYPE_I_INTERFERON_PRODUCTION | 68 | 19 | 17377 | 2626 |
DDX58,POLR2L,POLR2K,PRKDC,DHX9,FLOT1,POLR3GL,IRF3,POLR3K,IRF5,XRCC5,STAT6,CRCP,TICAM1,HMGB2,MAVS,RNF135,ZC3HAV1,IFI16 |
| 4.718e-03 | -5.36 | GSE40666_WT_VS_STAT1_KO_CD8_TCELL_UP | MSigDB lists | GSE40666_WT_VS_STAT1_KO_CD8_TCELL_UP | 187 | 42 | 17377 | 2626 |
WASF2,ADD1,CCM2,KLHL18,KLF13,SMC6,DOCK11,ASXL2,PIP4K2A,LMNA,TMCC3,CLIC4,INPP5A,INTS7,TBC1D14,DAPK1,ATG13,TIPARP,N4BP2,MSH6,SMC4,BIRC3,KIAA0040,CIC,LRBA,WBP2,EZR,ARHGDIB,RAB3IP,BICD2,SOX4,PHF6,RBM38,INF2,L3MBTL3,RBL1,TULP3,NCOA1,SRSF3,CBX4,TUBB,ESYT2 |
| 4.718e-03 | -5.36 | GSE5542_UNTREATED_VS_IFNA_AND_IFNG_TREATED_EPITHELIAL_CELLS_24H_DN | MSigDB lists | GSE5542_UNTREATED_VS_IFNA_AND_IFNG_TREATED_EPITHELIAL_CELLS_24H_DN | 187 | 42 | 17377 | 2626 |
PTMS,HSPH1,PRKAB1,ST13,LUZP1,RAF1,USP39,AGFG1,BCL2L1,ARF1,MAPK14,EXT2,GIT2,PHC2,FKBP1A,RINL,LRRC8D,DPYSL2,ATP13A3,SRI,AKR1B1,SEPT11,PTGES3,TIMM50,SAP30,SP3,SNX25,PHF20L1,ZNF672,TNFAIP3,PBXIP1,SEPT8,DNAJA1,TAZ,EIF4G2,SLCO4A1,SAFB,DBI,CCDC125,CLN3,CD81,MAPK1 |
| 4.718e-03 | -5.36 | GSE10273_HIGH_VS_LOW_IL7_TREATED_IRF4_8_NULL_PRE_BCELL_UP | MSigDB lists | GSE10273_HIGH_VS_LOW_IL7_TREATED_IRF4_8_NULL_PRE_BCELL_UP | 187 | 42 | 17377 | 2626 |
CCDC93,GOLIM4,COPA,GNPDA1,ANKH,HEXB,ABCB10,SECISBP2,ZNRF3,CMTM6,CPNE3,SLC25A36,UBXN2A,UCHL5,ADCY9,UBA5,RP2,ZNF710,TMED2,CAMK2G,ADCY7,LDHB,ENPP4,ELOVL5,DENND4C,OXR1,LACTB,MTMR6,CDC6,RHOB,INF2,GOLGA4,OSBPL8,ACOX1,SNAP23,ZNF367,GADD45B,APPL2,TMEM159,PGAM1,HIPK3,CCDC137 |
| 4.718e-03 | -5.36 | GSE12366_GC_VS_MEMORY_BCELL_DN | MSigDB lists | GSE12366_GC_VS_MEMORY_BCELL_DN | 187 | 42 | 17377 | 2626 |
PARP12,PLXNC1,TSC22D3,SLC2A1,ASAH1,TGOLN2,ADPGK,MAN2B1,CDC42SE2,NOTCH2,SNN,DUSP22,ZADH2,CHD1,ZNF275,CFLAR,SNX18,FAM89B,TAF5L,RNF19A,CSNK1G3,DRAM2,SRPK2,ZNF559,KAT2A,POLK,ATXN1,HERPUD2,MACF1,EML4,RHOB,MYO1F,SERTAD2,GOLGA8A,STAT1,ITGB1,ATF6,SPCS3,GALNT10,OSGEPL1,ZMIZ1,N4BP2L2 |
| 4.718e-03 | -5.36 | GSE26343_UNSTIM_VS_LPS_STIM_MACROPHAGE_DN | MSigDB lists | GSE26343_UNSTIM_VS_LPS_STIM_MACROPHAGE_DN | 187 | 42 | 17377 | 2626 |
TMEM106C,WASF2,CKLF,NOTCH2,LANCL1,MAPK14,PSEN1,PARN,CUTC,RFWD3,CDKN2C,USF1,ITGB8,LPIN2,SLC44A1,XPA,CNPY4,HADHB,ARL6IP1,ARL5A,CTDSP2,MSH6,ARHGAP17,TRAFD1,TCTEX1D2,POLR2G,CSRP1,HTATIP2,WDR81,MEF2D,RIT1,CYFIP2,POLR2A,ECH1,ARHGAP15,SGSH,OSBPL11,EIF2D,APPL2,MZT2B,RTN3,TIGD2 |
| 4.718e-03 | -5.36 | GSE5589_UNSTIM_VS_180MIN_LPS_AND_IL10_STIM_MACROPHAGE_UP | MSigDB lists | GSE5589_UNSTIM_VS_180MIN_LPS_AND_IL10_STIM_MACROPHAGE_UP | 187 | 42 | 17377 | 2626 |
RMND5A,CTDP1,SYS1,CAST,DAP,SLC2A1,PDXDC1,LMNA,XPR1,CFLAR,NUS1,SLC1A4,IARS,UBA5,SOCS6,AKR1B1,SEPT11,RPF2,AFF1,CYB5R1,NAP1L4,LDLRAD3,NAA35,MGAT5,MTX2,PCBP2,FYTTD1,KLF10,ETV3,USP22,ESYT1,SLC17A5,EIF3G,DNAJC10,RBM47,CCDC6,LIMK1,CTBS,ACLY,RRS1,TMEM159,CDKN2A |
| 4.718e-03 | -5.36 | GSE2770_UNTREATED_VS_ACT_CD4_TCELL_2H_UP | MSigDB lists | GSE2770_UNTREATED_VS_ACT_CD4_TCELL_2H_UP | 187 | 42 | 17377 | 2626 |
TCF12,NAT9,GPR132,SCAMP3,AGRN,ANXA6,B4GALT5,DNAJB2,TATDN3,C5orf30,KLHL18,LANCL1,EZH1,GGPS1,DDRGK1,MAN1A1,TMCC3,CAPN2,PPCDC,ORAI1,AHDC1,ETV3,PBXIP1,LDB1,LRRC8A,ATXN1,PLEC,LY6E,EDEM2,TAZ,SLC50A1,HHEX,TRIM26,PDLIM1,STAT1,DTX4,APPL2,NLRC5,PIEZO1,AKNA,ZBTB11,ABCA1 |
| 4.718e-03 | -5.36 | GSE25085_FETAL_BM_VS_ADULT_BM_SP4_THYMIC_IMPLANT_UP | MSigDB lists | GSE25085_FETAL_BM_VS_ADULT_BM_SP4_THYMIC_IMPLANT_UP | 187 | 42 | 17377 | 2626 |
WSB2,PARP12,MRPS2,PTTG1,PAWR,SLC35B1,BRIX1,BZW2,APP,SPPL2A,TMCC3,AHSA1,ZCCHC2,MVP,PPA1,TRIM14,ENPP4,KAT2A,ELL2,MRPL12,LY6E,OGFR,ZFAND5,FOXRED1,MAT2A,ISG15,GNAS,HLA-B,IDE,MTHFD2,SERF2,CERS6,PPM1G,GLG1,LMBR1,ATP6V0C,CHMP4B,PDXK,SRSF3,RBPJ,NR2F2,FAM208A |
| 4.718e-03 | -5.36 | GSE3039_ALPHABETA_CD8_TCELL_VS_B2_BCELL_DN | MSigDB lists | GSE3039_ALPHABETA_CD8_TCELL_VS_B2_BCELL_DN | 187 | 42 | 17377 | 2626 |
SRM,AP1B1,STMN1,PSMD9,TMEM165,EXT2,DDRGK1,HOMER1,NDUFA2,CBWD2,RALB,TIMM23,PPME1,MEGF8,ATIC,FNIP2,RNF19A,TACC3,MYO5A,SLC25A1,GINS1,NOL12,SNX8,METTL1,CCT2,SNX2,WDR18,POLR2D,MRPS10,GLO1,TMEM147,GALNT7,CLNS1A,QARS,NAGLU,NFIL3,APPL2,NAA20,REEP4,PDLIM5,SMURF1,ESYT2 |
| 4.718e-03 | -5.36 | GSE3982_NEUTROPHIL_VS_EFF_MEMORY_CD4_TCELL_DN | MSigDB lists | GSE3982_NEUTROPHIL_VS_EFF_MEMORY_CD4_TCELL_DN | 187 | 42 | 17377 | 2626 |
CCNC,DNMT3A,ABCC10,YTHDC2,STARD7,NENF,DCUN1D4,CCNA2,KLHL20,UTP18,SSBP3,BANF1,TNPO3,RPN2,TTC4,TCEA1,CYC1,PTGES3,MRPL40,SCYL3,ILKAP,EEF1D,MAPRE2,CSRP1,KAT2A,POLR2G,HARS,VHL,MRPL12,NUP155,CYFIP2,FANCE,MAT2A,STOML2,AKAP1,KIF2A,TTC13,ACYP1,PTER,CD81,FAM208A,ATMIN |
| 4.718e-03 | -5.36 | GSE3039_ALPHABETA_CD8_TCELL_VS_B1_BCELL_DN | MSigDB lists | GSE3039_ALPHABETA_CD8_TCELL_VS_B1_BCELL_DN | 187 | 42 | 17377 | 2626 |
TMEM106C,SLC12A7,SRM,HIVEP3,GCLM,IMMT,TP53RK,RRP15,MRPS2,DCTN2,KCTD17,NENF,INO80E,PSMD9,PA2G4,PSMD1,PELO,FIZ1,MECR,BRI3,FNIP2,ATP6V0D1,MYO5A,SLC25A1,SRP72,PLK3,NAGPA,MND1,LONRF3,TSTA3,ELL2,PLEC,MAP2K2,KIF2A,U2SURP,RBPJ,CENPT,SLC25A39,HRAS,NIPA1,TUBB,FAF1 |
| 4.718e-03 | -5.36 | V$EGR2_01 | MSigDB lists | V$EGR2_01 | 187 | 42 | 17377 | 2626 |
CMAS,GPR132,PDCD6IP,PLXNC1,DYNLL1,SUMO2,ANKH,PABPC4,XPR1,WDR48,WWP2,CDKN2C,TFAP4,NFATC3,ATP2A2,ITGB8,CD3EAP,SH3BP1,WDR44,RRBP1,NUP107,UPRT,GNAI2,FBXL19,DVL2,CGGBP1,CFL1,ERF,SYVN1,SOX4,HMGN2,MASTL,MAN2A2,AHNAK,SYNCRIP,ERGIC3,ATXN2L,PTPN7,AP1S1,ATP6V1C1,SMAD1,SLC25A39 |
| 4.718e-03 | -5.36 | GSE41867_NAIVE_VS_DAY8_LCMV_ARMSTRONG_EFFECTOR_CD8_TCELL_DN | MSigDB lists | GSE41867_NAIVE_VS_DAY8_LCMV_ARMSTRONG_EFFECTOR_CD8_TCELL_DN | 187 | 42 | 17377 | 2626 |
TCF12,PRKAB1,SMAP1,PPP1R12A,SLC2A1,CCM2,CHIC2,CCNL2,UBQLN2,MAP1LC3B,PIP4K2A,BCAP31,MFSD10,RNF103,SUB1,SIAH1,MBD2,XPA,FBXW2,ZFYVE27,MDFIC,EIF5,LRSAM1,SPSB3,MOB4,RHOA,ETV3,DCLRE1C,LY6E,SPPL2B,DDX23,MYO1F,KRIT1,SERTAD2,KPNA1,HSPB11,NSF,KLHL15,SLAIN1,ZMIZ1,BRD9,SNX14 |
| 4.724e-03 | -5.36 | cellular response to unfolded protein | biological process | GO:0034620 | 133 | 32 | 17256 | 2622 |
HSPH1,ADD1,SEC61G,CXXC1,RHBDD1,DNAJB9,LMNA,SSR1,RNF121,SHC1,MYDGF,PDIA6,CTDSP2,ATP6V0D1,PREB,DCTN1,BAK1,SEC61B,ERO1A,SYVN1,EDEM2,SERP1,OPTN,HSPA1B,YIF1A,SEC31A,DERL1,HSPA4,SEC61A1,TATDN2,ATF6,ASNA1 |
| 4.726e-03 | -5.35 | ficolin-1-rich granule | cellular component | GO:0101002 | 185 | 41 | 18223 | 2701 |
MIF,GMFG,DYNLL1,PDAP1,RAC1,ASAH1,CDK13,GYG1,MAPK14,KCMF1,TMEM179B,GNS,PSMD2,CTSS,ARPC5,HUWE1,OSTF1,MVP,ENPP4,TIMP2,RHOA,PPIE,PSMB7,C1orf35,ATP6V0A1,PKM,CCT8,CAND1,HSPA1B,CAT,PSMD3,ACLY,IMPDH1,CANT1,CAB39,ATP6V0C,GPI,MAPK1,LTA4H,PGAM1,CAPN1 |
| 4.726e-03 | -5.35 | Regulation of cytoplasmic and nuclear SMAD2/3 signaling | Pathway Interaction DB | smad2_3pathway | 19 | 9 | 2226 | 426 |
CALM2,SMAD2,NUP153,KPNA2,UBE2I,MAPK1,CTDSP2,SMAD4,MAPK3 |
| 4.748e-03 | -5.35 | cellular response to oxygen-containing compound | biological process | GO:1901701 | 924 | 169 | 17256 | 2622 |
RORB,MAX,H2AFZ,AGRN,SIRT2,SLC29A1,CCNB1,BECN1,MAPK14,PARK7,PRNP,EEF2K,CDK5,ABL2,USF1,RAB8A,RAP1A,PCNA,PIK3R2,DNM2,AKR1B1,TRA2B,DNMT1,PTPRK,CDC5L,LARS,KLF10,GABPA,AKT2,GNG7,EZR,CDC6,BRCA1,SOX4,PAF1,PRDX5,MPV17,ADAM9,ATP6V0C,ACTB,CHEK2,C2CD5,ATP6V0E1,HDAC2,PDCD4,SLC25A33,PHB2,AGTRAP,PRKAA1,LAMTOR3,PXMP2,PSEN1,ARID1B,CDC73,CFLAR,TFAP4,PDXP,DAPK1,TIMELESS,ATP6V0A2,CTR9,GNAI2,ATP6V0D1,CYFIP1,AACS,OXR1,SRSF5,ADRB2,PKM,ELK1,MTR,APPL1,RHOB,XRCC5,EPRS,CSK,NSMF,LAMTOR4,RUVBL2,MAP3K5,SNRNP70,CDK2,ADNP2,SMARCD1,DNMT3A,RWDD1,NQO1,RAB11B,UBR2,RAF1,WDTC1,RRAGC,IRF3,BCL2L1,ATP6V1B2,PRKACA,TWF2,LYN,APP,GNB2,PDK2,ATP6V0B,MDM2,CCNA2,SHC1,ADCY9,AKAP8,AHCYL1,SPIDR,HTRA2,ADCY7,ATP6V1G1,PPIF,SLC26A6,ATP6V0A1,SOCS7,ANKZF1,IDE,GUCY1B1,STAT6,STAT1,TICAM1,SCARB1,PPP5C,MAPK1,LRP8,ABCA1,GCLM,TWNK,BLM,AP3S1,ETS1,FOXO3,PTPN2,CAPN2,PDCD10,GRK2,PTEN,ARHGEF2,CREB1,STAT3,MYO5A,TGFB1,PDPK1,PPP3CA,RHOA,TNFAIP3,NET1,PRKDC,DENND4C,PRKAR1B,RANGAP1,KCNQ1,MEN1,PDE3B,PRDX1,MAPK3,CACNB1,ATP6V1D,UPF1,KIF18A,PLAA,PRDX3,WNT5B,E2F1,PKD2,HMGB2,ATP6V1C1,CPEB2 |
| 4.758e-03 | -5.35 | GSE37605_TREG_VS_TCONV_C57BL6_FOXP3_IRES_GFP_DN | MSigDB lists | GSE37605_TREG_VS_TCONV_C57BL6_FOXP3_IRES_GFP_DN | 139 | 33 | 17377 | 2626 |
GOLPH3L,RPLP2,SUMO2,UROD,HMG20A,CCDC28A,RPL11,GTF2F1,LYAR,GSTK1,MECR,PPA1,NSUN4,TMEM9,CARS2,GPX4,GBA,RPL38,SSR2,TMEM147,PDHX,RPS9,EIF3H,RAB2B,RPL36,HMGN2,EIF3K,SDHB,TIMM13,COX7A2L,CRCP,VPS4A,IGBP1 |
| 4.758e-03 | -5.35 | GSE4984_UNTREATED_VS_VEHICLE_CTRL_TREATED_DC_UP | MSigDB lists | GSE4984_UNTREATED_VS_VEHICLE_CTRL_TREATED_DC_UP | 139 | 33 | 17377 | 2626 |
TCF12,ORAI2,ULK3,DNMT3A,ATXN3,RPLP2,SELPLG,WDR13,RDH10,MCCC1,B4GALT1,CREBL2,RLF,SYNRG,APP,MTR,BSDC1,NSA2,GNS,TSC1,KPNA4,SERF2,CERS6,ZHX1,DTX4,IMPDH1,MLYCD,CRY2,CREB1,FAU,TOP1MT,FAM3A,CBX4 |
| 4.758e-03 | -5.35 | GO_RIBONUCLEOPROTEIN_GRANULE | MSigDB lists | GO_RIBONUCLEOPROTEIN_GRANULE | 139 | 33 | 17377 | 2626 |
RAC1,DHX9,TIA1,RBM4,PABPC4,CNOT3,EDC3,PSMA6,CDC42,GRSF1,DCP1A,YBX1,PABPC1,STAU1,DDX28,POLR2G,NSUN2,POLR2D,CIRBP,RPL6,FXR1,PATL1,BTBD1,UPF1,EIF4ENIF1,LSM6,ARNTL,ATXN2L,PQBP1,KHSRP,ACTB,SNRPG,TUBB |
| 4.779e-03 | -5.34 | phagosome maturation | biological process | GO:0090382 | 40 | 13 | 17256 | 2622 |
RAB14,ATP6V0B,ATP6V1D,RAB7A,ATP6V0A2,ATP6V0A1,ATP6V0C,CORO1A,ATP6V1C1,ATP6V1B2,ATP6V0E1,ATP6V0D1,ATP6V1G1 |
| 4.779e-03 | -5.34 | spindle localization | biological process | GO:0051653 | 40 | 13 | 17256 | 2622 |
ASPM,MAP4,ACTR3,ARHGEF2,MYH9,NUSAP1,NDE1,SPDL1,MCPH1,ESPL1,SPAG5,SAPCD2,DCTN1 |
| 4.779e-03 | -5.34 | positive regulation of mRNA catabolic process | biological process | GO:0061014 | 40 | 13 | 17256 | 2622 |
UPF1,POLR2G,HNRNPR,METTL14,BTG2,AGO2,KHSRP,YTHDF3,CNOT6L,METTL3,TOB1,PABPC1,ZC3HAV1 |
| 4.782e-03 | -5.34 | GRUETZMANN_PANCREATIC_CANCER_DN | MSigDB lists | GRUETZMANN_PANCREATIC_CANCER_DN | 198 | 44 | 17377 | 2626 |
TOMM20,ABCA3,DAP,RAF1,FKBP2,AP1B1,EPHX2,PABPC4,SSR1,BCAT2,WWP2,SLC1A4,RPL17,IL6ST,CRAT,LMAN1,PPIF,SEC61B,AMD1,RPS10,RPS24,KRAS,SLC25A5,PRPSAP1,RPS9,EIF3A,MAT2A,CYB5A,ISG15,MYO1F,MKNK1,NUCB1,HHEX,GOLGA4,RPL32,TMED10,ACOX1,SEL1L,ACADM,NCOA1,CLU,IGBP1,TOB1,SMAD4 |
| 4.794e-03 | -5.34 | frontal_lobe | COSMIC cancer mutations | frontal_lobe | 74 | 20 | 17385 | 2587 |
NRAS,NF1,VHL,KRAS,ESYT1,MEN1,MRPS14,MAP2K2,GNAS,CDKN2C,FGFR3,RAB8A,PTEN,MSH2,CDKN1B,TCOF1,H3F3A,HRAS,MSH6,CDKN2A |
| 4.806e-03 | -5.34 | GO_CDP_DIACYLGLYCEROL_METABOLIC_PROCESS | MSigDB lists | GO_CDP_DIACYLGLYCEROL_METABOLIC_PROCESS | 12 | 6 | 17377 | 2626 |
AGPAT3,CDS2,CDIPT,AGPAT2,LCLAT1,AGPAT1 |
| 4.806e-03 | -5.34 | GO_POSITIVE_REGULATION_OF_TRANSCRIPTION_ELONGATION_FROM_RNA_POLYMERASE_II_PROMOTER | MSigDB lists | GO_POSITIVE_REGULATION_OF_TRANSCRIPTION_ELONGATION_FROM_RNA_POLYMERASE_II_PROMOTER | 12 | 6 | 17377 | 2626 |
CTR9,PAF1,RTF1,BRD4,CDC73,GTF2F1 |
| 4.806e-03 | -5.34 | GO_LEUCINE_ZIPPER_DOMAIN_BINDING | MSigDB lists | GO_LEUCINE_ZIPPER_DOMAIN_BINDING | 12 | 6 | 17377 | 2626 |
PAWR,PMF1,AATF,ERC1,DAPK3,CDC5L |
| 4.806e-03 | -5.34 | GO_POSITIVE_REGULATION_OF_VACUOLE_ORGANIZATION | MSigDB lists | GO_POSITIVE_REGULATION_OF_VACUOLE_ORGANIZATION | 12 | 6 | 17377 | 2626 |
ADRB2,RALB,LRSAM1,PIP4K2A,SH3GLB1,PIP4K2C |
| 4.806e-03 | -5.34 | GO_EXIT_FROM_MITOSIS | MSigDB lists | GO_EXIT_FROM_MITOSIS | 12 | 6 | 17377 | 2626 |
CTDP1,CHMP2A,CHMP4B,CHMP7,UBE2C,PPP2R2D |
| 4.806e-03 | -5.34 | GO_OLIGOSACCHARIDE_CATABOLIC_PROCESS | MSigDB lists | GO_OLIGOSACCHARIDE_CATABOLIC_PROCESS | 12 | 6 | 17377 | 2626 |
MAN2B1,MANBA,NEU1,GM2A,CTBS,HEXB |
| 4.806e-03 | -5.34 | GO_NEGATIVE_REGULATION_OF_DNA_REPAIR | MSigDB lists | GO_NEGATIVE_REGULATION_OF_DNA_REPAIR | 12 | 6 | 17377 | 2626 |
TRIP12,OGG1,HELB,RNF169,POLQ,TERF2 |
| 4.806e-03 | -5.34 | BIOCARTA_RAB_PATHWAY | MSigDB lists | BIOCARTA_RAB_PATHWAY | 12 | 6 | 17377 | 2626 |
RAB8A,RAB6A,RAB1A,RAB11A,RAB7A,RAB4A |
| 4.806e-03 | -5.34 | HOLLEMAN_DAUNORUBICIN_B_ALL_DN | MSigDB lists | HOLLEMAN_DAUNORUBICIN_B_ALL_DN | 12 | 6 | 17377 | 2626 |
CTCF,SHOC2,RHOA,CTDSP2,ARID4A,PCBP2 |
| 4.806e-03 | -5.34 | GO_REGULATION_OF_DNA_DAMAGE_CHECKPOINT | MSigDB lists | GO_REGULATION_OF_DNA_DAMAGE_CHECKPOINT | 12 | 6 | 17377 | 2626 |
FEM1B,RFWD3,RPA2,CHEK2,BRD4,THOC1 |
| 4.806e-03 | -5.34 | GO_SMN_COMPLEX | MSigDB lists | GO_SMN_COMPLEX | 12 | 6 | 17377 | 2626 |
GEMIN5,DDX20,GEMIN6,GEMIN4,STRAP,GEMIN7 |
| 4.808e-03 | -5.34 | GSE30971_WBP7_HET_VS_KO_MACROPHAGE_4H_LPS_STIM_UP | MSigDB lists | GSE30971_WBP7_HET_VS_KO_MACROPHAGE_4H_LPS_STIM_UP | 171 | 39 | 17377 | 2626 |
MZT1,TXN,NOP2,TM9SF4,NF1,UCK2,UBE2Z,NIT2,GLRX3,GFM2,SRXN1,TNS3,PSMD1,ZNF473,PSMA6,ITGB8,TIMM23,TPST1,ATP6V0A2,GEMIN4,TALDO1,CDC37,ACSL5,PPIF,METTL1,PLK3,TNFAIP3,ODC1,PSMC4,DNAJC10,PLAA,NIP7,WDR4,AEN,BEND3,RRS1,LRP8,SLC25A33,TUBB |
| 4.808e-03 | -5.34 | GSE45365_CD8A_DC_VS_CD11B_DC_IFNAR_KO_DN | MSigDB lists | GSE45365_CD8A_DC_VS_CD11B_DC_IFNAR_KO_DN | 171 | 39 | 17377 | 2626 |
HSPH1,HJURP,PHF23,UCK2,ENSA,MRPL50,RBM23,AHSA1,ATIC,NDUFB9,FBXL19,EEF1D,EBAG9,VPS13B,SP3,PHF20L1,FAM49B,GOPC,OXR1,RDH10,SLC16A7,RPL8,GORASP2,FAM50B,TANC1,GAR1,TARS,EIF3H,XRCC5,TAF2,PCM1,UAP1,NSMCE2,UBXN2B,CAB39,TATDN1,MRPL13,RNF139,IFI16 |
| 4.822e-03 | -5.33 | MTOR (mechanistic target of rapamycin kinase) | protein interactions | 2475 | 175 | 42 | 17029 | 2761 |
RPS6KA1,SUZ12,PRKAA1,RRAGC,AKT1S1,BCL2L1,GNB2,RPL23A,FKBP1A,PA2G4,RAP1A,THADA,PTEN,ZNRF2,RP2,STAT3,MLST8,CDC37,PDPK1,TELO2,LARS,TNFAIP3,ASPM,MTA2,PRKDC,BRCA1,RAB1A,RHEB,MTMR3,FNTA,HSPA4,SYNCRIP,STK38,STAT1,PML,YWHAZ,RUVBL2,MAPK1,TERF1,SMAD4,DDB1,RHEBL1 |
| 4.826e-03 | -5.33 | S_TKc | smart domains | SM00220 | 349 | 68 | 9493 | 1367 |
TP53RK,RAF1,RPS6KA1,CSNK2A1,MAPK14,PRKACA,CDK5,PRKD3,NEK6,MAST2,SCYL3,CDK12,SRPK2,PLK3,PLK1,ULK3,AKT2,PBK,TAOK1,MAP4K4,TLK1,PKMYT1,AURKB,STK17B,MAP3K4,MKNK1,CLK3,HIPK2,STK38,STK11,CHEK2,ROCK1,RNASEL,MAPK1,CSNK1D,PRPF4B,TRIO,PRKAA1,CDK13,EIF2AK4,CDK11B,CSNK1A1,SCYL2,GRK2,DAPK1,MAP3K14,PHKG2,CAMK2G,CSNK1G3,PDPK1,CSNK1G2,MAPKAPK3,NEK7,EIF2AK1,MAP4K3,CDK11A,MAP2K2,MARK2,DAPK3,MAPK3,MASTL,NEK1,CSNK1G1,MAPK6,MAP3K5,RPS6KC1,CDK2,HIPK3 |
| 4.828e-03 | -5.33 | GSE21360_SECONDARY_VS_QUATERNARY_MEMORY_CD8_TCELL_DN | MSigDB lists | GSE21360_SECONDARY_VS_QUATERNARY_MEMORY_CD8_TCELL_DN | 155 | 36 | 17377 | 2626 |
MIF,SRGN,TCF3,MAGED1,SLC2A1,ARID5A,JMJD6,SNN,UBE2I,RAB11A,FBXO22,DTL,VAV1,TNFAIP8,SNX18,CD3EAP,CLDND1,SMARCE1,STAT3,FAM49B,EID1,OAF,MAP4K4,POLR2D,LDHA,NARF,STK17B,GALNT2,NFIL3,PTPN7,DMWD,RBPJ,PGAM1,CD81,ABCA1,EGLN1 |
| 4.840e-03 | -5.33 | adrenal_gland-pheochromocytoma | COSMIC cancer mutations | adrenal_gland-pheochromocytoma | 50 | 15 | 17385 | 2587 |
GNAS,FGFR3,RB1,MAX,NRAS,NF1,PTEN,VHL,PTPN11,KRAS,STK11,MEN1,HRAS,SMAD4,CDKN2A |
| 4.849e-03 | -5.33 | CSNK1E (casein kinase 1 epsilon) | protein interactions | 1454 | 170 | 41 | 17029 | 2761 |
USP39,WDR5,CSNK1A1,SEC16A,APP,PNO1,MTMR4,ARHGEF1,AXIN2,GTSE1,MICU2,CRY2,RP2,MAVS,AHCYL1,DVL2,VPS13B,RBX1,FOPNL,MTA2,KAT7,NSUN2,TAOK1,MIER1,TAZ,BTBD1,RAD54B,KIF2A,PCM1,FAM110A,DHX16,AXIN1,ARNTL,FAM83D,DTD1,KLHL42,DVL1,PPP6R3,CSNK1D,BYSL,SMARCD1 |
| 4.860e-03 | -5.33 | ovary-sex_cord-stromal_tumour-granulosa_cell_tumour | COSMIC cancer mutations | ovary-sex_cord-stromal_tumour-granulosa_cell_tumour | 32 | 11 | 17385 | 2587 |
GNAS,CDKN2C,DNMT3A,NRAS,PTEN,SF3B1,STK11,KRAS,BRCA1,HRAS,CDKN2A |
| 4.860e-03 | -5.33 | acinic_cell_carcinoma | COSMIC cancer mutations | acinic_cell_carcinoma | 32 | 11 | 17385 | 2587 |
NRAS,PTEN,ETV6,SAMD8,STK11,KRAS,LRRC1,SMAD4,HRAS,CDKN2A,SLC25A36 |
| 4.860e-03 | -5.33 | granulosa_cell_tumour | COSMIC cancer mutations | granulosa_cell_tumour | 32 | 11 | 17385 | 2587 |
GNAS,CDKN2C,DNMT3A,NRAS,PTEN,SF3B1,STK11,KRAS,BRCA1,HRAS,CDKN2A |
| 4.890e-03 | -5.32 | TRIM15 (tripartite motif containing 15) | protein interactions | 89870 | 42 | 14 | 17029 | 2761 |
VASP,KEAP1,TRIM8,SHC1,PTTG1,EHMT1,MYBL2,ACTB,ROCK1,BLM,CFL1,IRF5,PRNP,FERMT3 |
| 4.890e-03 | -5.32 | YIPF5 (Yip1 domain family member 5) | protein interactions | 81555 | 42 | 14 | 17029 | 2761 |
YIF1A,ELOVL5,COX5B,ATP1A1,MPHOSPH8,SLC38A5,PHB2,RAB7A,NABP2,PTAR1,YIF1B,MBOAT1,ATP5F1B,ATP5F1A |
| 4.890e-03 | -5.32 | CASP6 (caspase 6) | protein interactions | 839 | 42 | 14 | 17029 | 2761 |
SRP72,RB1,CASP6,CHD3,PIN1,MAPK6,XIAP,UBE4B,UBE4A,COPS6,PSEN1,APP,LMNA,CFLAR |
| 4.890e-03 | -5.32 | KLHL40 (kelch like family member 40) | protein interactions | 131377 | 42 | 14 | 17029 | 2761 |
FAM208B,AHNAK,MCM10,ZNF746,TYW1,PML,SLAIN1,DUSP11,KIF2C,FUS,VDAC1,FAM208A,CBX4,ZNF92 |
| 4.890e-03 | -5.32 | MSI2 (musashi RNA binding protein 2) | protein interactions | 124540 | 42 | 14 | 17029 | 2761 |
RPA2,FKBP1A,MDM2,WDR1,PIN1,SUZ12,RAB7A,H2AFX,CUL3,TARDBP,PABPC1,EIF3G,PABPC4,RPA1 |
| 4.890e-03 | -5.32 | MRPL18 (mitochondrial ribosomal protein L18) | protein interactions | 29074 | 42 | 14 | 17029 | 2761 |
MRPL50,MRPL2,MRPL9,CYLD,MRPL42,MPHOSPH8,MRPL39,PPP1R21,TUFM,DUSP11,MRPL13,MRPL19,MRPL3,MRPL32 |
| 4.890e-03 | -5.32 | TMEM43 (transmembrane protein 43) | protein interactions | 79188 | 42 | 14 | 17029 | 2761 |
DDX28,SIAH1,RAB7A,TOR3A,TBRG4,PPP6R2,RAB11A,BZW2,TSPAN5,SPPL2B,IFI16,LMNA,SRSF1,FDFT1 |
| 4.890e-03 | -5.32 | FNTA (farnesyltransferase, CAAX box, alpha) | protein interactions | 2339 | 42 | 14 | 17029 | 2761 |
TGFB1,FGFR3,NAP1L1,VAV2,CENPF,PTP4A3,KRAS,XRCC3,BRCA1,BLM,SAFB2,HRAS,RHOB,CAPN1 |
| 4.890e-03 | -5.32 | GLB1 (galactosidase beta 1) | protein interactions | 2720 | 42 | 14 | 17029 | 2761 |
PLK1,TRAPPC9,TK1,RHOA,DNAJB2,RHOC,PTPN7,H2AFX,CTSA,DNAJB1,XPNPEP3,CDK2,SFXN5,NEU1 |
| 4.899e-03 | -5.32 | CEBPZ (CCAAT enhancer binding protein zeta) | protein interactions | 10153 | 73 | 21 | 17029 | 2761 |
LZTR1,NOP2,ZNF512,MECP2,LAMTOR3,GTPBP4,EBNA1BP2,PRKRA,MAK16,YY1AP1,DDX56,SYNCRIP,NIP7,RBM34,RPS14,STAT6,ZNF746,NOC2L,CCDC59,IFI16,GPATCH4 |
| 4.899e-03 | -5.32 | UQCRFS1 (ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1) | protein interactions | 7386 | 73 | 21 | 17029 | 2761 |
USP7,RAB14,ATP5IF1,ACP2,SEPT9,TM9SF4,NDUFA4,CYCS,OAT,ATP5PF,SDHA,SDHB,NDUFV1,NDUFB4,NDUFA11,MPV17,ACAT1,MDH1,SRSF3,CYC1,NDUFS5 |
| 4.904e-03 | -5.32 | cytoplasmic vesicle membrane | cellular component | GO:0030659 | 757 | 138 | 18223 | 2701 |
TMED7,RAB14,COPA,ADAM10,ZDHHC8,SNX15,TAP1,AP3M2,TGOLN2,SEC16A,SYNRG,CMTM6,RAB8A,RAP1A,AP3S2,DBNDD1,RAB35,RAB4A,SRI,AP1M1,DNM2,AP2B1,KCNAB2,USO1,NRAS,CYSTM1,SLC17A5,MCFD2,RAB5B,RAB22A,NECAP2,AGPAT2,TMED10,RPS27A,ATP6V0C,C2CD5,ATP6V0E1,SVIP,DNAJC5,AGTRAP,HLA-E,RAB23,LAMTOR3,B4GALT1,TMED3,RAB6A,PSEN1,COPG2,COPB2,TMEM179B,CD59,SNX18,ZNRF2,ATP6V0A2,LPCAT1,ATP6V0D1,TMED2,KDELR1,VOPP1,ADRB2,PI4K2A,SEC31A,SCARB2,SNAP23,YWHAZ,UNC13C,EXOC3,RHOG,ANKRD27,ABCA3,RAB11B,DYNLL1,COPE,RAC1,VTI1A,BCL2L1,AP1B1,CPNE3,RAB21,ATP6V0B,APLP2,MDM2,SAR1A,BRI3,TAP2,CYB5R1,CORO1A,LMAN1,CLTB,TMBIM1,CPNE1,ENPP4,CLCN3,RAB7A,SLC26A6,ATP6V0A1,RAB1A,PEF1,ALDH3B1,CHMP4A,DDOST,SURF4,RAB24,SCAP,AP1S1,SCARB1,AP2S1,MANBA,SCYL1,TMX3,AP3S1,RAB11A,MFSD10,HLA-A,FZD6,TFRC,CLIC4,SEC24C,ZDHHC13,CAMK2G,RHOA,MLEC,DENND4C,KCNQ1,PICALM,HLA-B,RAB18,ATP6V1D,PDCD6,SEC23IP,MAGT1,WNT5B,SNAP29,PGRMC1,PKD2,PSAP,YWHAH,SNAPIN |
| 4.916e-03 | -5.32 | GO_IRON_ION_TRANSPORT | MSigDB lists | GO_IRON_ION_TRANSPORT | 54 | 16 | 17377 | 2626 |
FTL,RAB11B,ATP6V0A1,ATP6V1B2,PICALM,TFRC,SLC25A37,ATP6V0B,ATP6V1D,DNM2,ATP6V0A2,ATP6V0C,ATP6V1C1,ATP6V0E1,ATP6V0D1,ATP6V1G1 |
| 4.917e-03 | -5.32 | FBXO28 (F-box protein 28) | protein interactions | 23219 | 55 | 17 | 17029 | 2761 |
TRAF7,GOPC,DCTN2,PMF1,IKBIP,MCM2,LYN,EML4,GIT2,SPAG5,PLEKHF2,TMCC3,HOMER1,GOLGA2,PFDN4,TRAF5,NUP58 |
| 4.917e-03 | -5.32 | ARHGEF2 (Rho/Rac guanine nucleotide exchange factor 2) | protein interactions | 9181 | 55 | 17 | 17029 | 2761 |
RHOA,RAC1,FOXO3,USP21,MARK2,PRDX1,RPA1,ANKRD28,PPP2CA,RPA2,PPP6C,YWHAZ,YWHAH,MAPK1,PPP6R1,CDC5L,DCTN1 |
| 4.917e-03 | -5.32 | INTS1 (integrator complex subunit 1) | protein interactions | 26173 | 55 | 17 | 17029 | 2761 |
RPAP3,INTS2,CTDP1,DEAF1,INTS13,TGOLN2,POLR2A,NDUFS7,RPA1,PPP2CA,RPA2,INTS7,NABP2,INTS12,TCEA1,C7orf26,CDC5L |
| 4.917e-03 | -5.32 | CDC14A (cell division cycle 14A) | protein interactions | 8556 | 55 | 17 | 17029 | 2761 |
PLK1,MAPRE2,LUZP1,PRRC2A,BRAP,CDC6,CNTROB,EFL1,CCNB1,POLR2A,DAPK3,ODF2,KIAA1328,CHEK2,CDC25B,PPP6R1,POC5 |
| 4.917e-03 | -5.32 | GSE17721_CTRL_VS_POLYIC_0.5H_BMDC_UP | MSigDB lists | GSE17721_CTRL_VS_POLYIC_0.5H_BMDC_UP | 182 | 41 | 17377 | 2626 |
FEZ2,MOGS,LETMD1,GGPS1,LYRM2,BCAP31,EIF2S2,NEK6,MCM5,BANF1,PHTF1,ORC3,CITED2,LRRC59,CAMK2G,KCNAB2,KDELR1,MOB4,GABPA,LAP3,DENND4C,NSUN2,ANLN,ERC1,ANKRD46,ARF4,MFN2,AKAP1,BRMS1,JAK1,GOLGA7,BIRC5,LUC7L3,PARG,NRM,APPL2,HEXA,CPEB2,EYA2,ALS2,HDAC2 |
| 4.924e-03 | -5.31 | Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S | REACTOME pathways | R-HSA-72662 | 63 | 19 | 10287 | 1696 |
RPS15,EIF3L,RPS2,EIF3D,RPS10,RPS24,EIF4H,EIF3G,RPS9,RPSA,EIF3H,EIF3A,EIF3K,EIF2S2,RPS27A,RPS14,FAU,PABPC1,RPS26 |
| 4.930e-03 | -5.31 | ATPase activator activity | molecular function | GO:0001671 | 27 | 10 | 17224 | 2647 |
DNAJC2,DNAJC10,DNAJB2,AHSA1,TOR1AIP1,RAB4A,DNAJC24,TOR1AIP2,DNAJB1,DNAJA1 |
| 4.930e-03 | -5.31 | NF-kappaB binding | molecular function | GO:0051059 | 27 | 10 | 17224 | 2647 |
BRMS1,CPNE1,PSMA6,AKAP8,RNF25,TP53BP2,COMMD6,HDAC2,CDKN2A,FAF1 |
| 4.933e-03 | -5.31 | Citrate cycle (TCA cycle) | KEGG pathways | ko00020 | 30 | 11 | 7161 | 1149 |
SDHB,SUCLG1,IDH3A,MDH2,ACLY,CS,SUCLG2,MDH1,OGDH,IDH3B,SDHA |
| 4.933e-03 | -5.31 | Citrate cycle (TCA cycle) | KEGG pathways | hsa00020 | 30 | 11 | 7161 | 1149 |
SDHB,SUCLG1,MDH2,IDH3A,CS,ACLY,SUCLG2,MDH1,OGDH,IDH3B,SDHA |
| 4.938e-03 | -5.31 | GO_POSITIVE_REGULATION_OF_CELLULAR_COMPONENT_ORGANIZATION | MSigDB lists | GO_POSITIVE_REGULATION_OF_CELLULAR_COMPONENT_ORGANIZATION | 1082 | 194 | 17377 | 2626 |
ZBED3,PDCD6IP,AGRN,ZDHHC8,SIRT2,CCNB1,BECN1,MAPK14,MIEN1,PARK7,EEF2K,ABL2,CDK5,RAP1A,CDC42,SIVA1,DNM2,FNIP2,DNMT1,MLST8,BAK1,PLK1,ERCC1,SEPT9,NCK1,RBX1,AKT2,EZR,LRP5,AURKB,BRCA1,DPYSL3,STOML2,PAF1,MAP3K4,WAS,SMAD2,PSMD8,LIMK1,ITGB1,OGT,ADAM9,STK11,ROCK1,PIEZO1,CLU,VPS4A,DVL1,ARRB2,PSMC1,POT1,HDAC2,UBE2D3,GORASP1,PHB2,CIB1,KCTD17,NKD2,NCKAP1,RGS2,PSEN1,APOPT1,JMY,RB1,PDXP,VASP,ARPC5,MEGF8,XPA,CTR9,BCL2,LRSAM1,NSUN4,TERF2,EIF5A,CYFIP1,WDR1,ACSL3,PIP4K2C,RTF1,BCLAF1,ADRB2,SEPT7,CBFA2T2,ARPC1A,SF3A2,CCT8,MAP2K2,CAND1,FAS,PSMC4,TSC1,GOLGA4,GOLGA2,CDCA5,PPP3R1,ARAP1,CNOT6,YWHAZ,RUVBL2,RUFY3,WASF2,RHOG,ANKRD27,DYNLL1,RAC1,ANK3,CHD1L,ACTR3,STARD7,PLAGL2,TWF2,LYN,MOAP1,RRN3,RAB21,RALB,AKAP8,CDKN1B,TP53BP2,CYB5R1,CHTOP,LMAN1,HTRA2,PPIF,CCT2,PSRC1,PPT1,PSMB7,CUL3,TUBGCP5,WBP2,WIPF1,NFATC2,NUSAP1,RAB1A,TRIM28,USP36,IDE,SURF4,NSMCE2,CORO1C,CBLN2,SMURF1,MAPK1,SMAD4,LRP8,MECP2,FLOT1,CBLL1,ARF1,RAB11A,TUBGCP2,SCYL2,PIP4K2A,FBXO5,RPA2,KIF5B,PTEN,HUWE1,AXIN2,BRD7,H2AFY,SS18L1,ATG13,CREB1,CNOT6L,GTF2H2,TGFB1,PDPK1,RHOA,KAT2A,NET1,NEK7,MIER1,ANAPC2,MACF1,MARK2,NEU1,SH3GLB1,MAPK3,RPA1,BIRC5,STX18,TFDP1,E2F1,PML,UBE2C,YWHAH,ESPL1,HRAS,TERF1,DDB1,FAF1 |
| 4.943e-03 | -5.31 | exit from mitosis | biological process | GO:0010458 | 12 | 6 | 17256 | 2622 |
CHMP4B,CTDP1,CHMP2A,CHMP7,UBE2C,PPP2R2D |
| 4.943e-03 | -5.31 | positive regulation of vacuole organization | biological process | GO:0044090 | 12 | 6 | 17256 | 2622 |
LRSAM1,BECN1,RALB,PIP4K2A,SH3GLB1,PIP4K2C |
| 4.943e-03 | -5.31 | regulation of non-motile cilium assembly | biological process | GO:1902855 | 12 | 6 | 17256 | 2622 |
SEPT9,SEPT7,CENPJ,MAP4,ATMIN,DNM2 |
| 4.943e-03 | -5.31 | positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization | biological process | GO:1904925 | 12 | 6 | 17256 | 2622 |
ATP5IF1,SMURF1,OPTN,CDC37,GBA,MFN2 |
| 4.943e-03 | -5.31 | regulation of lysosomal lumen pH | biological process | GO:0035751 | 12 | 6 | 17256 | 2622 |
ATP6V0C,CLN3,PPT1,CLN6,TMEM165,SNAPIN |
| 4.943e-03 | -5.31 | regulation of attachment of spindle microtubules to kinetochore | biological process | GO:0051988 | 12 | 6 | 17256 | 2622 |
RACGAP1,SIRT2,CCNB1,CDC42,BECN1,SPAG5 |
| 4.948e-03 | -5.31 | regulation of generation of precursor metabolites and energy | biological process | GO:0043467 | 123 | 30 | 17256 | 2622 |
PPIF,NDC1,NUP188,RHOA,AKT2,NOA1,RAE1,PRKAA1,NUP54,PFKFB3,NUP155,CCNB1,PARK7,NUP205,PPP1R3B,NUP210,TIGAR,NUP107,OGT,NUP62,NUP153,ECD,STAT3,PGAM1,NUP85,NUP58,PHKG2,AAAS,SLC25A33,SEH1L |
| 4.952e-03 | -5.31 | CCAR2 (cell cycle and apoptosis regulator 2) | protein interactions | 57805 | 106 | 28 | 17029 | 2761 |
CYLD,MAGED1,CUL3,BRCA1,SMC2,PLEC,RPL27A,SEC16A,NCAPG,SF3A2,RPA1,RPA2,GSTK1,MDM2,MEX3C,NEK6,PSMD3,QARS,KBTBD7,ZNF335,TARDBP,CHEK2,RUVBL2,PDIA6,PSMC1,HTRA2,KCNAB2,SMC4 |
| 4.957e-03 | -5.31 | Kctd5 (potassium channel tetramerisation domain containing 5) | protein interactions | 69259 | 87 | 24 | 17029 | 2761 |
PDPK1,TCF12,CYFIP1,SEPT9,PHB2,POLK,SLC25A22,GORAB,SIRT2,SEC16A,GNB2,TFAP4,TET3,SUB1,AHNAK,NDUFB4,MTA1,LRPPRC,PKD2,SENP1,ATP6V0D1,TUBB,SMC4,DCTN1 |
| 4.957e-03 | -5.31 | CEP126 (centrosomal protein 126) | protein interactions | 57562 | 87 | 24 | 17029 | 2761 |
NAT9,TOMM20,FAM118B,KAT7,PBK,KIF15,EPN1,LRRC1,PMF1,PRKRA,FXR1,SPDL1,RGS2,RPA2,FGFR3,RBM23,EIF2S2,KLHL20,NSF,YWHAZ,SNRPG,TFG,LUC7L2,GEMIN7 |
| 4.960e-03 | -5.31 | poly-purine tract binding | molecular function | GO:0070717 | 23 | 9 | 17224 | 2647 |
SYNCRIP,EIF4A3,PPIE,TIA1,TRA2B,ATXN1,PABPC1,PATL1,PABPC4 |
| 4.961e-03 | -5.31 | GO_CORE_PROMOTER_SEQUENCE_SPECIFIC_DNA_BINDING | MSigDB lists | GO_CORE_PROMOTER_SEQUENCE_SPECIFIC_DNA_BINDING | 98 | 25 | 17377 | 2626 |
SP3,H2AFZ,KLF10,BAZ2A,SUZ12,WBP2,SMARCA4,THRAP3,SOX4,CREM,UBTF,RRN3,NRF1,STAT6,MTA1,NFIL3,ARNTL,ZNF335,STAT1,NLRC5,H2AFY,RBPJ,RUVBL2,SMAD1,H3F3A |
| 4.961e-03 | -5.31 | GTCNYYATGR_UNKNOWN | MSigDB lists | GTCNYYATGR_UNKNOWN | 98 | 25 | 17377 | 2626 |
PKP4,MLEC,PBXIP1,ERF,PGS1,SRSF6,CCDC34,MRPS10,MTX1,ODC1,STOML2,GALNT2,ETS2,THADA,ODF2,PHTF1,TBPL1,COX8A,AP1S1,YBX1,NUP153,PTPDC1,CHPF2,SLC35A1,TSPAN5 |
| 4.961e-03 | -5.31 | GO_N_ACYLTRANSFERASE_ACTIVITY | MSigDB lists | GO_N_ACYLTRANSFERASE_ACTIVITY | 98 | 25 | 17377 | 2626 |
NAT14,NAT9,GNPNAT1,KAT2A,KAT7,ELP4,EDF1,TAF6L,USP22,WDR5,SUPT7L,NMT2,SAP130,CERS6,OGT,NAA50,TAF5L,TAF12,NCOA1,NAA20,ATF2,SMARCE1,SAT2,NAA60,NCOA2 |
| 4.967e-03 | -5.31 | mitochondrial outer membrane | cellular component | GO:0005741 | 180 | 40 | 18223 | 2701 |
TOMM20,MTX3,PHB2,RAF1,STARD7,LETMD1,BCL2L1,SNN,SLC25A44,FOXO3,MIEF1,MOAP1,TIGAR,SLC44A1,HADHB,BCL2,CISD2,MAVS,ATF2,MTX2,TRIM14,ACSL5,BAK1,ACSL3,VDAC2,MCL1,MTX1,VDAC1,TOMM40,RHOT1,RHOT2,SH3GLB1,CYB5A,MFN2,AKAP1,ANKZF1,RPS27A,ATP5MC3,TOMM6,NIPSNAP2 |
| 4.975e-03 | -5.30 | regulation of cellular component biogenesis | biological process | GO:0044087 | 907 | 166 | 17256 | 2622 |
PDCD6IP,NPHP4,ADD1,AGRN,SIRT2,UBQLN2,PPP1R16B,MIEN1,BECN1,BIRC2,PARK7,EEF2K,DLG5,RAP1A,CDC42,ATG3,DNM2,FNIP2,MTPN,CARMIL1,MLST8,PLK1,ERCC1,SEPT9,RBX1,NCK1,GMFB,EZR,BRCA1,ANLN,CBFB,DPYSL3,TBC1D17,WAS,LIMK1,MAP4,ATXN2L,PIEZO1,CLU,ROCK1,VPS4A,SLF1,PSMC1,SVIP,TBC1D12,MAPRE1,HJURP,GMFG,PHF23,DNAJB2,RHOC,PRKAA1,KCTD17,NCKAP1,DNAJB1,RGS2,DOCK11,JMY,SPAG5,SUB1,RB1,VASP,SMC3,CCP110,ARPC5,XPA,CAPZA1,PIKFYVE,LRSAM1,TERF2,PREB,CYFIP1,LDB1,PIP4K2C,CAMSAP1,GBA,UTP15,BCLAF1,CAPZA2,SEPT7,ARPC1A,DAPK3,PSMC4,XRCC5,CAND1,TSC1,ORMDL2,ARAP1,NUP62,SAMD8,CNOT6,PDLIM5,RHOG,WASF2,CHMP2A,ANKRD27,CYLD,FEZ2,RAF1,ACTR3,RAC1,CHD1L,TBC1D13,PRKACA,TWF2,STMN1,STAM,RRN3,RALB,TBC1D22A,TBC1D14,KIF14,CDKN1B,CORO1A,SPIDR,DCTN1,PSRC1,RAB7A,VDAC2,WIPF1,CHMP2B,USP36,PEX5,IDE,CHMP4A,CORO1C,CBLN2,NCLN,CHMP4B,H3F3A,SMAD4,ABCA1,ATMIN,MECP2,CDT1,FLOT1,ARFIP2,ARF1,PIP4K2A,RPA2,PTEN,CENPJ,PTPN11,ARHGEF2,CREB1,CNOT6L,GTF2H2,RNF5,SPTAN1,TGFB1,RHOA,TCTEX1D2,KAT2A,MACF1,SH3GLB1,RPA1,HSPA1B,MTMR3,HGS,STX18,PARP10,HRAS,TERF1,SLF2,FAF1,DDB1 |
| 4.981e-03 | -5.30 | GO_PHAGOCYTIC_VESICLE | MSigDB lists | GO_PHAGOCYTIC_VESICLE | 83 | 22 | 17377 | 2626 |
RAB14,CLCN3,RAB11B,HLA-E,RAB7A,RAB23,ATP6V0A1,BECN1,ITGB5,RAB11A,RAB22A,HLA-A,HLA-B,RAB8A,ATP6V0B,ATP6V0A2,ATP6V0C,CORO1A,ATP6V0E1,ATP6V0D1,ABCA1,ANXA11 |
| 4.981e-03 | -5.30 | GO_HYDROLASE_ACTIVITY_ACTING_ON_CARBON_NITROGEN_BUT_NOT_PEPTIDE_BONDS_IN_LINEAR_AMIDES | MSigDB lists | GO_HYDROLASE_ACTIVITY_ACTING_ON_CARBON_NITROGEN_BUT_NOT_PEPTIDE_BONDS_IN_LINEAR_AMIDES | 83 | 22 | 17377 | 2626 |
NADSYN1,ATXN3,WDYHV1,MTA2,RCOR1,ASAH1,NIT2,SIRT2,AMDHD2,MBD3,BRMS1,CAT,CHD3,HDAC7,MTA1,RBBP4,NGLY1,SAP30L,ARID4A,HDAC2,PDF,SAP30 |
| 4.981e-03 | -5.30 | GO_ACETYLTRANSFERASE_COMPLEX | MSigDB lists | GO_ACETYLTRANSFERASE_COMPLEX | 83 | 22 | 17377 | 2626 |
KAT2A,KAT7,ELP4,TAF6L,USP22,SUPT7L,WDR5,MEAF6,SAP130,TAF2,MBIP,BRPF3,OGT,NAA50,ACTB,TAF5L,RUVBL2,TAF12,NAA20,TAF6,NAA35,USP34 |
| 4.990e-03 | -5.30 | DVL1 (dishevelled segment polarity protein 1) | protein interactions | 1855 | 64 | 19 | 17029 | 2761 |
CYLD,RAC1,NKD2,CSNK2A1,WWP2,CXXC4,SMAD2,CCP110,HUWE1,AXIN1,BRD7,DVL1,SMAD1,HDHD2,SMAD4,DVL2,CSNK1D,DCTN1,USP13 |
| 4.990e-03 | -5.30 | NDUFB9 (NADH:ubiquinone oxidoreductase subunit B9) | protein interactions | 4715 | 64 | 19 | 17029 | 2761 |
NDUFA5,IMMT,NDUFS1,TIMMDC1,VDAC2,ILF3,LAMTOR3,MEF2A,NDUFA4,ATP5F1B,ATP5MF,RAB1A,NDUFS7,SDHB,RPN1,NDUFA2,MPV17,NDUFS5,ABCC1 |
| 4.990e-03 | -5.30 | POLR2H (RNA polymerase II subunit H) | protein interactions | 5437 | 64 | 19 | 17029 | 2761 |
UNK,SNRNP200,DNMT3A,POLR2I,POLR2G,POLR2L,POLR2K,ELOA,POLR2D,BRCA1,PSMB9,POLR2A,POLR2J,MED10,INTS1,CRCP,POLR1B,RUVBL2,ZNRD1 |
| 4.990e-03 | -5.30 | FKBP1A (FK506 binding protein 1A) | protein interactions | 2280 | 64 | 19 | 17029 | 2761 |
TGFB1,PPIF,PPIB,PPP3CA,TXN,RAE1,UFC1,FKBP2,TOMM40,MCM2,APP,FKBP1A,MDM2,HINT1,PIN1,PPP3R1,TAGLN2,YY1,GPX4 |
| 4.991e-03 | -5.30 | GSE15930_NAIVE_VS_72H_IN_VITRO_STIM_CD8_TCELL_UP | MSigDB lists | GSE15930_NAIVE_VS_72H_IN_VITRO_STIM_CD8_TCELL_UP | 193 | 43 | 17377 | 2626 |
CDS2,NQO1,AGRN,KLHL21,PHRF1,RAE1,STRN4,ALKBH5,PCSK7,JMJD6,SPR,C19orf48,GGPS1,APP,SUB1,ZKSCAN1,SIAH1,DDA1,CRY2,CYB5R1,CLTB,METTL1,TIMP2,IDH3A,MAP4K3,ADRB2,SOX4,EIF4H,POLG2,LUC7L,USP21,SF3A2,SPPL2B,BSDC1,HSPA1B,PI4K2A,SURF4,TULP3,CANT1,DVL1,GALNT10,BRWD3,USF2 |
| 4.991e-03 | -5.30 | GSE43955_TH0_VS_TGFB_IL6_TH17_ACT_CD4_TCELL_4H_UP | MSigDB lists | GSE43955_TH0_VS_TGFB_IL6_TH17_ACT_CD4_TCELL_4H_UP | 193 | 43 | 17377 | 2626 |
GPR132,PHB2,GADD45G,AGFG1,RGS2,PSEN1,LYN,CMTM6,RPA2,FKBP1A,EIF2S2,ZNF260,ANP32A,BIRC3,FAM49B,TBRG4,WDHD1,DNAJC9,WDR82,TANC1,OGFR,ZFAND5,GAR1,NEU1,ZFR,ADSS,FBXO21,OSBPL11,PARG,NFIL3,ZNF436,PGRMC1,STK11,BTF3,B4GALT3,BRWD3,CHMP7,MRPL13,PTDSS1,TSPAN5,PARD3,ZNF146,HDAC2 |
| 4.991e-03 | -5.30 | GSE2770_UNTREATED_VS_IL4_TREATED_ACT_CD4_TCELL_6H_DN | MSigDB lists | GSE2770_UNTREATED_VS_IL4_TREATED_ACT_CD4_TCELL_6H_DN | 193 | 43 | 17377 | 2626 |
MZT1,HNRNPUL2,C16orf87,CDCA3,C19orf25,TOP2B,MBD4,PAIP2,SF3B2,HERC3,NFATC3,ADD3,AHCTF1,METTL14,ZNF746,PPP6R1,SPSB3,NIPSNAP1,EID1,DENND1B,WIPF1,SLBP,LNX2,NFATC2IP,CBFB,KIF11,TFEB,GNA12,PCM1,MID1IP1,TXNDC16,DSN1,L3MBTL3,CSK,ZNF367,ZC3H7B,C4orf46,NCOA1,TCOF1,IDH3B,USP11,HIPK3,MRPL3 |
| 4.991e-03 | -5.30 | GSE17721_CTRL_VS_GARDIQUIMOD_6H_BMDC_DN | MSigDB lists | GSE17721_CTRL_VS_GARDIQUIMOD_6H_BMDC_DN | 193 | 43 | 17377 | 2626 |
PPP1R37,TP53RK,THOC1,FAM129A,EIF3D,CHIC2,BCL2L1,CHD1,LIN9,KRI1,SLC31A1,RRN3,SHC1,MBD2,DDA1,POP7,TRA2B,MDFIC,OSTC,LRRC59,NAA35,HDHD2,PDCL3,MORC3,TXNL1,MOB4,USO1,BIRC3,HARS,WBP2,USP10,FAM50B,CYFIP2,ETS2,CLK3,HNRNPH3,ITGB1,BCL7C,ZNF436,RGL1,AKNA,CD81,IPO4 |
| 4.991e-03 | -5.30 | GSE360_T_GONDII_VS_B_MALAYI_LOW_DOSE_MAC_DN | MSigDB lists | GSE360_T_GONDII_VS_B_MALAYI_LOW_DOSE_MAC_DN | 193 | 43 | 17377 | 2626 |
TMEM184B,UBN1,DAP,RAE1,KIAA0232,VPS45,BCL2L1,PMF1,FKBP2,PSMD9,PIP4K2A,HDDC2,RNF103,SH3BP1,PIN1,FBXO7,ARHGEF2,PCYT2,CYB5R1,NAP1L4,UBE3C,CLTB,CTDSP2,SRSF10,ERCC1,RHOA,ATG9A,ZNF202,FAM50B,LY6E,CHAF1A,MYO1F,SDHB,ALDH3B1,POLR2J,GPS2,ACOX1,CAPN7,NAGLU,TAF12,ZMIZ1,LTA4H,PDCD11 |
| 4.991e-03 | -5.30 | GSE23568_ID3_KO_VS_WT_CD8_TCELL_DN | MSigDB lists | GSE23568_ID3_KO_VS_WT_CD8_TCELL_DN | 193 | 43 | 17377 | 2626 |
MIF4GD,UGP2,TOR3A,CDT1,PTP4A3,EIF2AK4,GGA2,LYN,MBD4,IRF4,SLC31A1,ATP6V0B,CLIC4,STRBP,INPP5A,TPST1,TTC4,ZNRD1,MTPN,GM2A,MYO5A,POU2AF1,PPP3CA,SNX2,ELL2,PSPC1,KIAA0930,SLC16A7,ADRB2,IRF5,NECAP2,HHEX,ZNF282,TXNDC16,CSK,PML,E2F1,ADAM9,ATF6,PDXK,CHEK2,CD81,ABCA1 |
| 4.996e-03 | -5.30 | GSE8685_IL2_ACT_IL2_STARVED_VS_IL21_ACT_IL2_STARVED_CD4_TCELL_UP | MSigDB lists | GSE8685_IL2_ACT_IL2_STARVED_VS_IL21_ACT_IL2_STARVED_CD4_TCELL_UP | 166 | 38 | 17377 | 2626 |
H2AFZ,PLXNC1,CLSPN,VAV2,CERK,XIAP,NDUFA4,HMGN3,PLXNA1,GYG1,FOXO3,EBP,APLP2,TNFAIP8,SNX18,HUWE1,KIF14,LPIN2,KNTC1,AHCYL1,RPAP3,CYFIP1,ERMP1,OXR1,CAMSAP1,DCTD,PSMB9,PICALM,IRF5,PPP2CA,TWSG1,NFIL3,CTSA,ACTB,MAP3K5,CD81,E2F2,AP2S1 |
| 5.025e-03 | -5.29 | haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm | 7517 | 1179 | 17385 | 2587 |
ZBTB10,TSC2,CMTM6,RBM4,ANKRD39,FBXO22,RPL23A,EEF2K,NAPG,DNAAF2,ATP13A3,DNM2,LRRC59,MGAT5,USP34,CCDC57,ERCC1,RHOBTB3,NRAS,EHMT1,KIF15,HNRNPF,WDHD1,MIER2,KRIT1,AHNAK,SMAD2,RAD18,MYO18A,COX5A,SMAD1,ZNF75A,ANXA11,SMNDC1,PDCD4,SLC25A33,NXT2,HIVEP3,CLSPN,MUM1,TRIO,DHX9,RAB23,EIF2AK4,APH1B,PSMD9,PARN,CDC73,HAUS2,COPB2,TFAP4,PDXP,SMC3,MEGF8,EFTUD2,MVP,NUP85,PPP6R1,PABPC1,PPA1,LUC7L2,EIF3L,IFRD1,AGGF1,FOXK1,TYW1,GTPBP4,USP10,MRPL16,EIF4H,SFXN5,RDH11,KPNA1,TXNDC16,PDLIM1,ETS2,TYW5,WIPI2,PDLIM5,ACSF2,MRPL3,EXOC3,TRIM41,NQO1,POC1A,ANK3,VTI1A,INO80E,SLC35B2,LCLAT1,CPNE3,KIAA1147,ABHD16A,RBM23,ZNF420,AHCTF1,TBC1D22A,SH3BP1,UBA5,CLCN6,SEPT11,INTS12,GPD1L,ZC3H3,RPRD1B,PDCL3,GOPC,RPL38,E2F3,PFKFB3,TANC1,RAB1A,GIGYF1,TMEM184C,PPP2CA,LSM6,VPS26B,NSMCE2,CORO1C,CAMKMT,RNF38,DMWD,PPP5C,PITRM1,USP13,COMMD10,MZT1,ZFP91,HABP4,CCM2,BTN3A1,SLC25A43,NEIL2,GOLM1,CLIC4,ITGB8,ZNF260,NAA50,LTN1,UBE3B,NAP1L4,ST8SIA2,STAU1,DDX24,TCTEX1D2,C14orf132,RAB3IP,PICALM,UTP20,SH3BP5,SLC19A1,ACOX1,FAM3C,PARP10,FAM129A,YTHDC2,NENF,SND1,PAPOLA,ZER1,CREM,KRR1,TET3,FANCL,NUP210,NT5DC1,IL6ST,SLC44A1,NOC2L,MTPN,TACC3,RYBP,VPS13B,PTPN18,CELSR2,MIOS,RBX1,PSMG1,CKAP2L,PBRM1,EAF2,ALG3,TRAM2,FBXO28,ZNF367,ADAM9,BEND6,NGLY1,NUMB,FAM53C,CENPF,SDC2,ADCK5,CDK13,RAB6A,NCKAP1,TNS3,MLX,UBE2Q2,CCP110,MBD2,ZNF746,AHCY,GLE1,LRSAM1,NIPSNAP1,NTPCR,ABHD2,NSDHL,AMD1,MAP4K3,METTL22,STYXL1,APPL1,RBM38,NMT2,MBIP,PCM1,GALNT2,TMEM168,COX7A2L,SIL1,DTD1,MYO9A,BTBD10,UNC13C,USP7,ARID2,NDUFAF2,TMX4,TOR1AIP1,SLC2A1,TM9SF3,RRAGC,ATP6V1B2,PCBP1,LYN,VAV1,NRF1,ZNF473,BRPF3,WDR44,PPME1,EFCAB11,RPAP1,BCAP29,TOP1MT,AHCYL1,LMAN1,STRAP,ZNF583,PRPF19,SNX25,KDM3B,MND1,CLCN3,BIRC3,ANKRD33B,PPIE,NUP155,CHMP2B,VDAC1,MRPS14,EIF3H,RHBDF2,GLOD4,IDE,DHX16,RBL1,STK38,UHRF2,H3F3A,CHID1,SMAD4,PARD3,SLC30A9,NADSYN1,KLHL21,PDAP1,TMX3,HMGN3,TUBGCP2,FZD6,HERC3,HOMER1,CTSS,ORC3,YTHDC1,RPRD1A,RHOA,BTAF1,METTL5,TOP3A,ARHGEF12,RANGAP1,PNPLA8,PCGF1,ZFR,RAB18,SEC23IP,L3MBTL3,E2F1,TMEM219,HIPK3,IFI16,TXN,NUP188,GXYLT1,ADAM10,CXXC1,CUL1,OAT,MYEF2,SLC25A37,ANKRD26,NOL11,TRA2B,CISD2,CDC5L,SRP72,OSBP2,NSUN2,USP22,RAB2B,EIF3A,PRIM1,IWS1,ZMYM3,TPP2,LUC7L3,MAP4,BTF3,NMD3,RECQL,COX5B,EWSR1,SCOC,PRKAA1,ANKH,RRM1,DLGAP4,TATDN3,B4GALT1,PXMP2,PSEN1,TMEM165,NDUFS7,SPAG5,WDR48,C12orf10,RPN1,EXOSC7,LHX8,KLHL5,ZNRF2,MSH2,DAPK1,TPST1,FBXL7,OSTF1,FAM171A1,FDFT1,GCC2,PRIM2,ELL2,EMB,RDH10,MFNG,ARID1A,FXR1,PTTG1IP,C9orf40,CCT8,MTR,PHF6,PI4K2A,XRCC5,DERL1,CAT,SLCO4A1,HSPBP1,TTC13,GOLGA2,MED15,PIAS2,FAM83D,USP32,APPL2,CABIN1,GPI,CDKN2A,NUDT3,ATXN3,RAF1,KIAA0232,POMP,C2orf49,CD320,EPM2A,DECR1,RALB,MTMR4,LPIN2,ADCY9,MRPS27,TTC3,AQR,ILKAP,CDK12,SAP30,CDC123,ELP4,ASB13,ERC1,EML4,SUPT16H,EIF3K,ZNF282,DGCR8,SAFB,LMBR1,ATF6,BEND3,EYA2,ADAM23,B4GALT5,MECP2,MANBA,TKT,CBLL1,ARGLU1,SECISBP2,LANCL1,HEATR5B,SLC25A36,WWP2,FUT8,AXIN2,PTPN11,RPL19,CNN2,MTX2,MSH6,PDLIM2,JMJD4,PACS1,KCNQ1,KIF11,KLF6,GUF1,MACF1,SMAP2,MYO1F,TMEM127,DDX5,WDR91,WDR62,DDB1,FAM83G,DEF6,POLA2,UBL3,LYRM4,COPA,HMGXB3,PTP4A3,ABCB10,PCYOX1L,RAB35,JAZF1,HADHB,GPATCH1,DRAM2,CARM1,WDR41,LARS,DEAF1,ZCCHC10,SNRNP200,CCDC138,NCK1,LAP3,LRBA,KMT2C,OGFR,ASF1B,RPL37,HSPB11,EIF4ENIF1,MIA2,BAZ1B,STK11,VPS4A,CLU,CHPT1,MRPL13,TSTD2,ATP6V0E1,DCAF5,CAPN1,UBE2D3,PPP1R2,PPP1R12A,ZCCHC8,THRAP3,QSOX2,NUP205,PRPF18,DTL,ZRANB1,SLC12A2,CSNK1G3,TRAFD1,NUDT4,EIF2A,SYVN1,SLTM,DAPK3,ARHGAP15,EVC2,UAP1,SIAH2,FN3KRP,EHD4,C11orf1,ADNP2,CHMP2A,CORO7,PMS2,UCK2,SMARCA4,ORC1,UBXN2A,NVL,KIF14,CS,CLTB,DNAL4,CSTF1,POU2AF1,PCGF6,ATXN1,OGDH,CADM1,BICD2,HERPUD2,PDHX,RPS9,PON2,HNRNPR,STAT6,ARNTL,ANP32E,FKBP5,MAPK1,ABCA1,TMEM33,PDF,DNAJC2,TRIP12,RAE1,SHPRH,DCTN2,NUP54,VPS45,CHIC2,PAWR,MXD4,DCUN1D4,GFM2,PIP4K2A,XPR1,SPPL2A,FERMT3,KLHL20,SEC24C,PPIG,H2AFY,LDLRAD3,ERI3,STAT3,FRMD8,SLC35A1,MYO5A,NIPAL3,TGFB1,ELOVL5,FAM49B,PSPC1,SCFD2,RFFL,RCOR1,COG1,NDRG3,TFEB,LEMD2,UPF1,ELMO1,MEGF9,ACAT1,ZMIZ1,HRAS,ZSWIM6,CCDC93,ADD1,KDM4A,DHX8,GLUD1,PPP1R16B,CALM2,PSMD1,RABGAP1L,TTC9C,PDS5B,NUP153,KCNAB2,PLEKHM3,MCL1,DCUN1D5,PWWP2B,WDR11,AXIN1,LIMK1,ATE1,SMG9,E2F2,LONP2,PFKP,SSRP1,NDUFV2,MRPL9,CERK,TOP2B,SLC4A2,EZH1,ITGB5,LMNA,MCTS1,DDRGK1,RAVER2,GNS,EIF2S2,INTS7,PHF14,CARS2,UBE2QL1,RB1CC1,DHX29,PGS1,MAN1B1,TEX10,MYBL2,UHRF1BP1,CBFA2T2,ABCF1,MATR3,NCDN,CYB5A,LRRC14B,PTPRF,SCARB2,OSBPL11,SETD3,CNOT6,HEXA,SNX14,EGLN1,PPP1R37,ANKRD27,SARNP,ABCA3,TRERF1,IVNS1ABP,UBR2,CHD1L,ACTR3,TMEM97,WDTC1,MYH9,PRKACA,APP,ANKIB1,STAM,TMEM161B,ARL6IP6,PRKD3,RAB21,ATP2A2,UTP18,GRSF1,ZCCHC2,NUP107,ANKRD13C,FAM76B,CLN6,ATF2,TMEM9,RNF169,ATP6V1G1,ADCY7,ENPP4,SHOC2,MAP4K4,CDCA2,FKBP3,CHCHD3,SEC61A1,HIPK2,RPLP1,WDR7,MBOAT1,PDXK,LRCH1,RPS2,TMBIM4,SESTD1,TRAK1,UBE4A,ETS1,ZNF92,KRI1,FBXO3,CAPN2,ADD3,DCP1A,TMX1,HNRNPM,IMPA2,NUDC,PPP3CA,GUK1,TNFAIP3,POLK,GALC,ZNF512,KIAA0930,MTMR12,PDE3B,RPA1,ZNF862,KIF18A,CCDC6,LRPPRC,C4orf46,LY75,HMGB2,RGL1,WDR76,USF2,IGBP1,FAF1,DDX47,AGRN,THOC1,GNPDA1,MCCC1,CDC42SE2,BIRC2,GIT2,ATPAF1,LIN9,DLG5,ETV6,ZFYVE27,MCMBP,MYBL1,CCAR1,MRPL32,CDC37,ABCC5,MRPL12,EZR,LNX2,LRP5,ANLN,STX16,RHEB,DPYSL3,TONSL,NRM,NAGLU,QRSL1,ACTB,PIEZO1,ZNF45,GLCCI1,LZTR1,CTCF,PPP3CB,DOCK11,RLF,CRLF3,VMP1,PPIL2,SLC27A4,TIMELESS,AHDC1,MDFIC,MAML1,TRAPPC9,AACS,MEMO1,KRAS,ARPC1A,GOLGA4,PRPS2,RNF114,CYLD,UGP2,MRPL39,SUMO2,COPE,DUSP22,GGPS1,COMMD8,MDM2,STRBP,CORO1A,MINPP1,METTL9,SLC39A9,CLPTM1,PSMA8,COQ10B,BTG2,CPOX,CYP20A1,MTMR6,NFATC2,PRPF3,KDM1B,ARL5B,TXNL4A,DNAJC10,ATP1A1,SCAP,CLK3,DNAJC17,ZNF436,NCOA1,LTA4H,INTS2,CTDP1,GOLIM4,CDC40,MIF4GD,RRP15,DAP,GNE,ARID5A,SMC6,SUMF1,CHAC2,GGA2,BZW2,TFRC,WRNIP1,PTPN2,SLC1A4,CWC27,SLC35B4,ABCD1,DDX31,PTGES3,RPAP3,MLEC,CNTN5,SNX2,CHCHD6,TPD52L2,KPNA4,GOLGA7,TFE3,CDCA7L,GLG1,PKD2,RPS6KC1,CHMP7,TMEM41B,TAP1,YTHDF3,PLXNA1,IKBIP,COMMD6,ELMOD2,ASAP2,SNUPN,CYB5RL,PARPBP,PLCL2,DNMT1,SEH1L,NOL12,ORAI2,DDX20,GALNT7,CCNF,MCFD2,TMED10,WDR4,EIF2D,DHTKD1,UQCRH,TRAF5,RTN3,SVIP,DDX58,WSB2,PPIB,MAPRE1,MUT,HLA-E,KIF23,SLC35B1,NOTCH2,MAN2B1,METTL3,COPG2,NDUFS4,RNF121,BDH1,ATP6V0A2,PIKFYVE,RNF135,LPCAT1,GNAI2,EEF1D,TERF2,SEPT8,PLEC,TOMM40,KDM3A,SF3A2,FAS,ADSS,EPRS,ZFP92,NSF,DCK,QARS,ERGIC3,LPCAT4,MAP3K5,YY1,CABLES1,ZC3HAV1,DNMT3A,RPS6KA1,SUZ12,SF3B1,EIF3D,OLA1,KLHL18,ADPGK,PHC2,FLAD1,CRKL,APLP2,KDM2A,SHC1,UCHL5,CDKN1B,NAA35,CDKN2AIP,CCT2,RFC3,MAPRE2,MKLN1,CUL3,SLBP,GALK2,POLG2,SHCBP1,AP4E1,DHX57,PRDM11,VEZF1,JAK1,PPP2R5A,TBL3,STAT1,PPA2,KLHDC4,PDCD11,ATMIN,POLQ,OTUD5,POU3F2,PKP4,TCF3,MRI1,SLC25A12,AGPAT3,MYNN,BLM,SPR,RAB11A,REEP5,FOXO3,CCDC28A,TMCC3,RBM17,PTEN,CRAT,UPF2,IFT46,PACS2,TSHZ1,ZFP64,NEK7,DENND4C,PARP4,RPL8,TBRG4,LRRC1,RHOT1,ECH1,GNA12,FBXO21,C1orf131,HGS,PRDX3,MFAP1,STX18,TFDP1,CCDC69,ASNA1,BRWD3,ESYT2,MIB2,SKA3,NPHP4,UBE2E2,PLXNC1,NOP2,ST13,TMEM184B,ALKBH5,DNAJC24,ZNF107,SIRT2,USP48,SNRPD3,MAPK14,SNAPC4,EDC3,UBLCP1,ZNF804A,THADA,EIF4A3,AP3S2,ZNHIT6,IMPAD1,ATG3,DPYSL2,RCSD1,PHTF1,AKR1B1,RP2,NFU1,TECR,ARID4A,TRIM14,FYTTD1,TDP1,TRIM8,SLC16A7,STK17B,DHX15,ABHD5,GEMIN5,CXXC4,IARS2,GALNT10,SASS6,STARD3NL,SLC12A7,TBC1D12,PIGN,MED13L,TIA1,EPHX2,SRRT,RHBDD1,KIFAP3,BCL2,GLTP,KNTC1,UBE3C,N4BP2,ZNF189,HP1BP3,VOPP1,OXR1,THNSL1,SEPT7,CAND1,GNAS,TSC1,NAP1L1,EXOC4,KIAA1328,ZFP90,NUP62,PITPNA,NAA20,PTDSS1,PDSS2,WASF2,MMACHC,IMMT,ASH1L,MPHOSPH8,GNPNAT1,WDYHV1,HNRNPUL2,CHD1,PAIP1,MEAF6,CCDC50,AKAP8,PARL,RPN2,APOOL,CHTOP,F2R,ABI1,MOSPD1,ACSL5,FAM172A,ZNF500,NLN,NDUFB1,BUD13,BTBD1,RAD54B,DAP3,TAB2,TULP3,GADD45B,WDR59,SCARB1,GAS2,AKNA,SMURF1,TSPAN5,KIF3B,CDS2,GOLPH3L,CASP6,EYA1,DBF4,MRPS26,KLF13,MFSD10,HDDC2,MAN1A1,GART,CTNNBL1,YIF1B,TTC17,GINS1,ZDHHC18,ADAM17,ASPM,PPP1R21,PRKAR1B,MEN1,ZNF407,TARS,MAPK3,MFN2,ATAD2,PLAA,OSBPL8,MBD6,TATDN1,IDH3B,ATP6V1C1 |
| 5.027e-03 | -5.29 | GO_POLYUBIQUITIN_BINDING | MSigDB lists | GO_POLYUBIQUITIN_BINDING | 36 | 12 | 17377 | 2626 |
UBQLN4,TNFAIP3,RAD18,TAB2,DNAJB2,UBXN1,RAD23B,ZRANB1,PARP10,RNF169,RAD23A,OPTN |
| 5.027e-03 | -5.29 | GO_AP_TYPE_MEMBRANE_COAT_ADAPTOR_COMPLEX | MSigDB lists | GO_AP_TYPE_MEMBRANE_COAT_ADAPTOR_COMPLEX | 36 | 12 | 17377 | 2626 |
GGA1,AP3S2,AP3M2,AP1M1,AP1S1,AP2B1,AP1B1,GGA2,AP3S1,SYNRG,PICALM,AP2S1 |
| 5.027e-03 | -5.29 | GO_ENDOPLASMIC_RETICULUM_ORGANIZATION | MSigDB lists | GO_ENDOPLASMIC_RETICULUM_ORGANIZATION | 36 | 12 | 17377 | 2626 |
RAB18,SEC61A1,VMP1,STX18,ARL6IP1,TOR1AIP2,ASNA1,LMAN1,SEC16A,RTN3,WRB,TMEM33 |
| 5.027e-03 | -5.29 | GO_SIGNAL_SEQUENCE_BINDING | MSigDB lists | GO_SIGNAL_SEQUENCE_BINDING | 36 | 12 | 17377 | 2626 |
KPNA4,TOMM20,PEX5,KPNA1,BRAP,AP2B1,TNPO3,TNPO2,NUP153,KPNA2,IPO4,KDELR1 |
| 5.027e-03 | -5.29 | HU_ANGIOGENESIS_DN | MSigDB lists | HU_ANGIOGENESIS_DN | 36 | 12 | 17377 | 2626 |
HNRNPA2B1,HMGN1,H2AFZ,NDUFB6,HMGN4,POLR2K,ITM2A,MDH1,GPI,H2AFV,DHX15,ATP6V1G1 |
| 5.027e-03 | -5.29 | GO_TRANSLESION_SYNTHESIS | MSigDB lists | GO_TRANSLESION_SYNTHESIS | 36 | 12 | 17377 | 2626 |
DTL,RPA2,PCNA,RFC3,POLK,RPS27A,USP10,RFC2,MAD2L2,NPLOC4,ISG15,RPA1 |
| 5.027e-03 | -5.29 | REACTOME_PI3K_AKT_ACTIVATION | MSigDB lists | REACTOME_PI3K_AKT_ACTIVATION | 36 | 12 | 17377 | 2626 |
PDPK1,MDM2,RHOA,TSC2,PTEN,AKT2,PIK3R2,CDKN1B,AKT1S1,CREB1,FOXO3,MLST8 |
| 5.027e-03 | -5.29 | TERAO_AOX4_TARGETS_SKIN_UP | MSigDB lists | TERAO_AOX4_TARGETS_SKIN_UP | 36 | 12 | 17377 | 2626 |
METTL1,ANKRD26,RNF121,PA2G4,HMGN1,DNAJC5,RAD23B,BCLAF1,TOMM40,ERC1,VPS29,KRIT1 |
| 5.027e-03 | -5.29 | GO_DNA_REPAIR_COMPLEX | MSigDB lists | GO_DNA_REPAIR_COMPLEX | 36 | 12 | 17377 | 2626 |
ERCC1,POLE,PRKDC,XPA,RAD23B,PMS2,MSH2,RCOR1,DCLRE1C,XRCC4,MSH6,XRCC5 |
| 5.037e-03 | -5.29 | ZnF_C2C2 | smart domains | SM00440 | 6 | 4 | 9493 | 1367 |
POLR2I,TCEA1,ZNRD1,POLR3K |
| 5.037e-03 | -5.29 | DAX | smart domains | SM00021 | 6 | 4 | 9493 | 1367 |
DVL1,AXIN1,DVL2,AXIN2 |
| 5.037e-03 | -5.29 | SWAP | smart domains | SM00648 | 6 | 4 | 9493 | 1367 |
SUGP1,CHERP,SUGP2,U2SURP |
| 5.045e-03 | -5.29 | DNA Damage Bypass | REACTOME pathways | R-HSA-73893 | 50 | 16 | 10287 | 1696 |
RFC3,RBX1,POLK,USP10,RFC2,MAD2L2,NPLOC4,ISG15,RPA1,RPA2,DTL,PCNA,RAD18,POLE,RPS27A,DDB1 |
| 5.046e-03 | -5.29 | RUTELLA_RESPONSE_TO_HGF_DN | MSigDB lists | RUTELLA_RESPONSE_TO_HGF_DN | 226 | 49 | 17377 | 2626 |
HLA-E,TMX4,TIA1,MED13L,PTP4A3,ARGLU1,GTF3A,NOTCH2,RGS2,PPP1R16B,HDDC2,DECR1,APLP2,DPYSL2,ANP32A,MAP3K14,METTL9,PLCL2,CNPY3,IMPA2,AMPD2,CYTH1,ZDHHC18,MAPRE2,SEPT9,KLF10,GALC,NET1,PGS1,MAP4K4,NARF,CIRBP,HEBP2,MCL1,NFATC2IP,ICAM2,ZFAND5,STK17B,MAN2A2,SH3BP5,ETS2,WNT5B,GADD45B,CCDC69,NCOA1,NDE1,LTA4H,TRAF5,CHPT1 |
| 5.053e-03 | -5.29 | PARN (poly(A)-specific ribonuclease) | protein interactions | 5073 | 22 | 9 | 17029 | 2761 |
UPF1,TULP3,SUMO2,KHSRP,UPF2,PARN,SPATC1L,BYSL,CSTF1 |
| 5.053e-03 | -5.29 | SIX2 (SIX homeobox 2) | protein interactions | 10736 | 22 | 9 | 17029 | 2761 |
CHMP2A,EYA1,THNSL1,APP,MARK2,EYA2,ANKHD1,CDKN2A,SUPT16H |
| 5.053e-03 | -5.29 | WDR19 (WD repeat domain 19) | protein interactions | 57728 | 22 | 9 | 17029 | 2761 |
NTPCR,NEK7,TULP3,ACSL3,TKT,DDX39A,RAD51D,PFKP,NIPSNAP1 |
| 5.053e-03 | -5.29 | CASP8AP2 (caspase 8 associated protein 2) | protein interactions | 9994 | 22 | 9 | 17029 | 2761 |
SP100,SCOC,SUMO2,PML,BCL2L1,UBE2I,FADD,FAS,CREM |
| 5.053e-03 | -5.29 | PANK4 (pantothenate kinase 4) | protein interactions | 55229 | 22 | 9 | 17029 | 2761 |
TERF2IP,RANGAP1,TPD52L2,TP53RK,EFL1,UBE3C,RMC1,NSUN2,EEF2K |
| 5.053e-03 | -5.29 | MAML1 (mastermind like transcriptional coactivator 1) | protein interactions | 9794 | 22 | 9 | 17029 | 2761 |
RMND5A,EWSR1,HUWE1,SMARCA4,RBPJ,PBRM1,NOTCH2,ZMIZ1,MAML1 |
| 5.053e-03 | -5.29 | NUDT5 (nudix hydrolase 5) | protein interactions | 11164 | 22 | 9 | 17029 | 2761 |
RPA2,TRIM47,SKA3,EWSR1,PPP1R12A,MAPK6,CUL1,SMURF1,NUDT3 |
| 5.053e-03 | -5.29 | ZNF398 (zinc finger protein 398) | protein interactions | 57541 | 22 | 9 | 17029 | 2761 |
ZNF282,ZNF777,NDE1,ELMO1,MFAP1,ZNF746,PLEKHF2,C1orf109,OPTN |
| 5.053e-03 | -5.29 | GCFC2 (GC-rich sequence DNA-binding factor 2) | protein interactions | 6936 | 22 | 9 | 17029 | 2761 |
SNRNP200,SYNCRIP,UBR2,ATXN1,CSNK2A1,ECD,SLF2,PRPF19,DDX23 |
| 5.053e-03 | -5.29 | TH (tyrosine hydroxylase) | protein interactions | 7054 | 22 | 9 | 17029 | 2761 |
KDM3B,MTFR2,CSNK2A1,YWHAZ,CDK11B,MAPK1,PRKACA,CAMK2G,MAPK3 |
| 5.053e-03 | -5.29 | GLRX5 (glutaredoxin 5) | protein interactions | 51218 | 22 | 9 | 17029 | 2761 |
BOLA3,KEAP1,TXN,CHCHD2,BOLA1,ARF1,ATP5F1A,APP,GLOD4 |
| 5.053e-03 | -5.29 | PTBP2 (polypyrimidine tract binding protein 2) | protein interactions | 58155 | 22 | 9 | 17029 | 2761 |
UBE2E2,HNRNPAB,GOLGA2,KHSRP,FUS,MATR3,RBM4,SNRPA,CDC5L |
| 5.053e-03 | -5.29 | Mtx2 (metaxin 2) | protein interactions | 53375 | 22 | 9 | 17029 | 2761 |
CHCHD3,RPN2,IMMT,MTX3,VDAC1,PHB2,CHCHD6,VDAC2,CCDC127 |
| 5.053e-03 | -5.29 | DMPK (DM1 protein kinase) | protein interactions | 1760 | 22 | 9 | 17029 | 2761 |
UBQLN4,TK1,PPP1R12A,PIN1,RAF1,RAC1,RPS10,ATXN1,GEMIN4 |
| 5.053e-03 | -5.29 | RGPD8 (RANBP2-like and GRIP domain containing 8) | protein interactions | 727851 | 22 | 9 | 17029 | 2761 |
IER2,UCHL5,NUP107,MIA2,NUP153,FAM136A,PMF1,MCM2,IFI16 |
| 5.053e-03 | -5.29 | SEPT1 (septin 1) | protein interactions | 1731 | 22 | 9 | 17029 | 2761 |
SEPT1,SEPT9,MYO18A,SEPT11,SEPT8,AURKB,SEPT7,TOLLIP,APP |
| 5.053e-03 | -5.29 | EDNRA (endothelin receptor type A) | protein interactions | 1909 | 22 | 9 | 17029 | 2761 |
HDAC7,LMBR1,PXMP2,MCL1,MTX1,ARL5B,ARRB2,GNAI2,EBP |
| 5.053e-03 | -5.29 | MKRN1 (makorin ring finger protein 1) | protein interactions | 23608 | 22 | 9 | 17029 | 2761 |
UBE2D3,CSNK1G1,SNRNP70,RRS1,LUC7L,MAP1LC3B,PABPC1,FADD,LUC7L2 |
| 5.053e-03 | -5.29 | AZGP1 (alpha-2-glycoprotein 1, zinc-binding) | protein interactions | 563 | 22 | 9 | 17029 | 2761 |
CYLD,MCM5,GTPBP4,NUF2,DDX31,MCM2,CDK2,USP53,ABCC1 |
| 5.070e-03 | -5.28 | STAT3 (signal transducer and activator of transcription 3) | protein interactions | 6774 | 279 | 62 | 17029 | 2761 |
FAM208B,FOXM1,TRIP10,IVNS1ABP,CHTF18,RAC1,ARFIP2,SMARCA4,STMN1,LYN,SRRT,GNB2,HLA-A,RPL11,PTPN2,RPA2,ABL2,RB1,FGFR3,SIAH1,IL6ST,PIK3R2,PTPN11,SRI,MSH2,CTR9,SS18L1,RP2,CORO1A,CREB1,STAT3,DNMT1,LUC7L2,HNRNPM,BRD4,MBLAC2,BRCA1,SUPT20H,ADRB2,USP22,ERBIN,GSTCD,TRIM28,RPS9,ECH1,MAPK3,SOCS7,IDE,KPNA1,BRWD1,JAK1,STAT6,STAT1,PML,SIAH2,NCOA1,SMAD1,MAPK1,CAPN1,HDAC2,SSSCA1,NXT2 |
| 5.077e-03 | -5.28 | DCTN2 (dynactin subunit 2) | protein interactions | 10540 | 111 | 29 | 17029 | 2761 |
MAPRE1,CYLD,CCDC138,TRIM11,DCTN2,STRN4,CUL3,POLR2D,PSMA1,BICD2,CAPZA2,MCFD2,POLR2A,PSMC4,GOLM1,HGS,PSMD1,FBXO28,MYO18A,MAPK6,CAPZA1,UQCRH,KPNA2,SMURF1,PSMC1,CCAR1,SEH1L,DCTN1,CDC5L |
| 5.077e-03 | -5.28 | LRPPRC (leucine rich pentatricopeptide repeat containing) | protein interactions | 10128 | 111 | 29 | 17029 | 2761 |
COA3,STAU1,TIMMDC1,IVNS1ABP,RAB7A,MAGED1,RAC1,ILF3,PTP4A3,HEBP2,AURKB,ADRB2,EIF2AK4,CAPZA2,RAB1A,MCM2,METTL22,HAUS2,GSTK1,WAS,BABAM2,MEX3C,NEK6,ZNF746,LRPPRC,CRY2,LMAN1,CDK2,SMURF1 |
| 5.081e-03 | -5.28 | positive regulation of multi-organism process | biological process | GO:0043902 | 176 | 40 | 17256 | 2622 |
MIF,PPIB,CTDP1,CHMP2A,POLR2K,TRIM11,YTHDC2,AGO2,DHX9,CIB1,SMARCA4,SIRT2,CHD1,GTF2F1,RAD23A,TMEM250,TFAP4,SMC3,ZNF639,MDFIC,LRSAM1,PABPC1,CFL1,SRPK2,STAU1,POLR2I,POLR2L,POLR2G,RAB7A,PPIE,POLR2D,CHMP2B,ZP3,POLR2A,OPTN,MAPK3,POLR2J,CHMP4B,VPS4A,DDB1 |
| 5.091e-03 | -5.28 | Ubiquitin-like_domsf | interpro domains | IPR029071 | 184 | 41 | 18492 | 2768 |
UBL3,SNX27,TMUB1,RAF1,UBXN1,SUMO2,MYO9B,USP48,UBQLN2,MAP1LC3B,NPLOC4,UBLCP1,RAD23A,UBXN2A,SNRNP25,RAD23B,FBXO7,AXIN2,NSFL1C,TP53BP2,TECR,DVL2,UBQLN4,GABPA,PCGF6,EZR,NFATC2IP,HERPUD2,ISG15,EPB41,AFDN,RPS27A,AXIN1,UBXN2B,UHRF2,VCPIP1,DVL1,RGL1,MYO9A,FAU,FAF1 |
| 5.103e-03 | -5.28 | SAGA-type complex | cellular component | GO:0070461 | 28 | 10 | 18223 | 2701 |
TAF2,KAT2A,TAF5L,SUPT20H,TAF12,USP22,TAF6L,SUPT7L,TAF6,SGF29 |
| 5.109e-03 | -5.28 | protein phosphatase regulator activity | molecular function | GO:0019888 | 77 | 21 | 17224 | 2647 |
ANKLE2,PPP1R9B,SHOC2,PPP1R37,PPP1R2,PPP1R15B,ENSA,PPP1R16B,CALM2,PPP1R3B,UBXN2A,PPP2R5A,UBXN2B,PPME1,PPP1R8,PPP4R1,NSFL1C,PPP1R11,CABIN1,IGBP1,PPP2R2D |
| 5.121e-03 | -5.27 | GSE14000_4H_VS_16H_LPS_DC_TRANSLATED_RNA_DN | MSigDB lists | GSE14000_4H_VS_16H_LPS_DC_TRANSLATED_RNA_DN | 177 | 40 | 17377 | 2626 |
GLT8D1,CASP6,TSC22D3,RAC1,C5orf30,RAB23,TBC1D13,EZH1,CCNL2,TMCC3,FANCL,CLUAP1,LRRC8D,MTMR4,GRSF1,PRC1,NAP1L4,DVL2,HEMK1,ERLIN1,DNAJC9,RAB3IP,LRRC1,C9orf40,KLF6,CYB5A,POLR2A,C19orf54,KIF2A,TMEM41A,CDC16,TWSG1,CEP55,LY75,RUFY3,SLC22A23,TRAF5,USP53,POT1,RHEBL1 |
| 5.121e-03 | -5.27 | GSE21546_WT_VS_SAP1A_KO_AND_ELK1_KO_ANTI_CD3_STIM_DP_THYMOCYTES_DN | MSigDB lists | GSE21546_WT_VS_SAP1A_KO_AND_ELK1_KO_ANTI_CD3_STIM_DP_THYMOCYTES_DN | 177 | 40 | 17377 | 2626 |
HIVEP3,MPHOSPH8,TRIM11,CENPF,MCCC1,CERK,KIF23,SMARCA4,ABHD14B,SNN,CDKN2C,ABL2,IRF4,NRF1,CCNA2,INPP5A,PDS5B,GTSE1,CDC25B,GPD1L,N4BP2,ELOF1,TTPAL,PLK1,RHOA,TNFAIP3,PBXIP1,OXR1,EHMT1,RAB3IP,PDE3B,ASF1B,TBC1D17,DCK,ARNTL,ADAM9,NDE1,UBE2C,E2F2,LRCH1 |
| 5.121e-03 | -5.27 | GO_ORGANELLE_DISASSEMBLY | MSigDB lists | GO_ORGANELLE_DISASSEMBLY | 177 | 40 | 17377 | 2626 |
TMEM203,MRPS2,KLC1,ATG2B,BECN1,GFM2,MCTS1,ATG4A,RFWD3,KIF5B,MEX3C,SLC1A4,ATG3,RIMS3,DNAAF2,FBXO7,TXLNA,ANXA5,NDUFB9,ATG13,CISD2,C8orf59,ZNF189,CDC37,PLK3,TMEM39A,ATG9A,SNRPB,CRNKL1,MRPS10,MARK2,PI4K2A,GOLGA2,EIF2D,COX8A,MDH1,WIPI2,SMURF1,CDKN2A,PFKP |
| 5.123e-03 | -5.27 | basal transcription machinery binding | molecular function | GO:0001098 | 58 | 17 | 17224 | 2647 |
ERCC1,CTDP1,BRD4,AGO2,DHX9,ELP4,LLPH,RTF1,CDC73,PAF1,ZNHIT6,ZNF326,CTR9,RUVBL2,FBL,RPRD1B,ELOF1 |
| 5.123e-03 | -5.27 | basal RNA polymerase II transcription machinery binding | molecular function | GO:0001099 | 58 | 17 | 17224 | 2647 |
ERCC1,CTDP1,BRD4,AGO2,DHX9,ELP4,LLPH,RTF1,CDC73,PAF1,ZNHIT6,ZNF326,CTR9,RUVBL2,FBL,RPRD1B,ELOF1 |
| 5.132e-03 | -5.27 | REACTOME_MITOCHONDRIAL_PROTEIN_IMPORT | MSigDB lists | REACTOME_MITOCHONDRIAL_PROTEIN_IMPORT | 45 | 14 | 17377 | 2626 |
TIMM8B,TOMM20,TIMM13,TIMM17A,CS,SLC25A12,MTX1,CYC1,TOMM40,VDAC1,TAZ,GFER,MTX2,TIMM50 |
| 5.132e-03 | -5.27 | GNF2_SELL | MSigDB lists | GNF2_SELL | 45 | 14 | 17377 | 2626 |
HLA-B,WAS,GMFG,OSBPL8,STAT6,ARHGDIB,MCL1,CORO1A,DAZAP2,CNPY3,ARRB2,LYN,CMTM6,GIT2 |
| 5.132e-03 | -5.27 | GNF2_HLA-C | MSigDB lists | GNF2_HLA-C | 45 | 14 | 17377 | 2626 |
VAV1,HLA-B,CYTIP,CORO7,WAS,MAX,HLA-E,STAT6,TSC22D3,TAP1,ARHGDIB,CORO1A,SERP1,HLA-A |
| 5.132e-03 | -5.27 | GO_CHAPERONE_MEDIATED_PROTEIN_FOLDING | MSigDB lists | GO_CHAPERONE_MEDIATED_PROTEIN_FOLDING | 45 | 14 | 17377 | 2626 |
FKBP1A,CCT2,PPIB,HSPH1,ST13,TTC9C,DNAJC24,CSNK2A1,FKBP5,CLU,PTGES3,DNAJB1,FKBP2,FKBP3 |
| 5.140e-03 | -5.27 | CTSA (cathepsin A) | protein interactions | 5476 | 38 | 13 | 17029 | 2761 |
RHOA,DNAJB2,RHOC,SUMO2,NAXE,CTSA,OAT,CDK2,SFXN5,BZW2,ABHD14A,LMNA,NEU1 |
| 5.140e-03 | -5.27 | PSAT1 (phosphoserine aminotransferase 1) | protein interactions | 29968 | 38 | 13 | 17029 | 2761 |
THADA,STAT6,ARF5,RAC1,MAPK6,CAB39,TAGLN2,TALDO1,AHCYL1,CDK2,PCBP1,APP,ARF4 |
| 5.140e-03 | -5.27 | OXSR1 (oxidative stress responsive 1) | protein interactions | 9943 | 38 | 13 | 17029 | 2761 |
RNASEH2C,RPL17,BTF3L4,ADSL,ANP32A,ICMT,SLC12A2,SMURF1,API5,APP,PFKP,USP5,CDC5L |
| 5.140e-03 | -5.27 | L3MBTL3 (L3MBTL3, histone methyl-lysine binding protein) | protein interactions | 84456 | 38 | 13 | 17029 | 2761 |
PHC2,LZTR1,SP100,POLR2L,L3MBTL3,SNRPB,PRKAA1,RBPJ,PRMT2,ASB6,PLEKHF2,BYSL,MAPK3 |
| 5.140e-03 | -5.27 | ABRAXAS2 (abraxas 2, BRISC complex subunit) | protein interactions | 23172 | 38 | 13 | 17029 | 2761 |
ANKRD28,HNRNPA2B1,USP7,CYTIP,BABAM2,TRAF7,HUWE1,BABAM1,ARRDC1,STK11,THAP5,DEF6,WWP2 |
| 5.140e-03 | -5.27 | MCAT (malonyl-CoA-acyl carrier protein transacylase) | protein interactions | 27349 | 38 | 13 | 17029 | 2761 |
USF1,DDX28,EWSR1,MRPS15,MRPL39,RBMX,TAP1,RBM3,HNRNPDL,REEP5,SPTAN1,RXRB,TFEB |
| 5.140e-03 | -5.27 | FBXL5 (F-box and leucine rich repeat protein 5) | protein interactions | 26234 | 38 | 13 | 17029 | 2761 |
PLK1,RBX1,TTC9C,CENPF,NABP2,CUL1,ARHGDIB,MAP7D1,ACTB,COPS6,CITED2,SMURF1,DCTN1 |
| 5.140e-03 | -5.27 | METTL1 (methyltransferase like 1) | protein interactions | 4234 | 38 | 13 | 17029 | 2761 |
NUCB1,TPD52L2,TP53RK,ARPC5,PRKDC,RPS6KA1,ACTR3,WDR4,PPA2,DNAAF5,PDLIM5,NPLOC4,PRDX1 |
| 5.146e-03 | -5.27 | Cajal body | cellular component | GO:0015030 | 60 | 17 | 18223 | 2701 |
SART1,FAM118B,HABP4,PRPF3,GAR1,LSG1,OIP5,HNRNPA2B1,ZNF473,EFTUD2,ICE2,PRPF4,FBL,CDK2,COIL,SMNDC1,DDX42 |
| 5.154e-03 | -5.27 | regulation of DNA recombination | biological process | GO:0000018 | 73 | 20 | 17256 | 2622 |
TGFB1,EXOSC6,THOC1,RAD51AP1,HELB,MRNIP,BLM,TFRC,TERF2IP,RPA2,KPNA1,STAT6,KLHL15,PARPBP,MSH2,KPNA2,SPIDR,MSH6,TERF2,POLQ |
| 5.165e-03 | -5.27 | PLK1 signaling events | Pathway Interaction DB | plk1_pathway | 44 | 16 | 2226 | 426 |
KIF2A,PPP2CA,PLK1,RHOA,GOLGA2,PPP1R12A,CLSPN,GORASP1,TPX2,CDC25B,CCNB1,RAB1A,BORA,CENPU,NUDC,FBXO5 |
| 5.172e-03 | -5.26 | FBXW7 (F-box and WD repeat domain containing 7) | protein interactions | 55294 | 311 | 68 | 17029 | 2761 |
CCNC,MAX,CYLD,FOXM1,CUL1,EBNA1BP2,PA2G4,NAPG,EIF4A3,PIN1,FBXW2,NDUFB9,CRY2,SNX8,PLK1,RPL29,DPM1,RBX1,SMU1,MCL1,SUMF2,AURKB,DCLRE1C,DIDO1,PRPSAP1,USP36,DDX17,HIPK2,FKBP5,COPS6,SINHCAF,SSRP1,CTDP1,POLR2K,RAE1,EYA1,SHPRH,MED13L,SPDL1,PSEN1,RFWD3,MED10,MED8,PTEN,ARL6IP1,YBX1,STAT3,SLC35A1,MED22,MYO5A,UBE2QL1,PHF20L1,TMEM126B,RCOR1,MAP7D1,KRAS,DDX39A,ZFR,MAPK3,MASTL,CCDC6,RBMX,MED15,FAM83D,ACLY,SNRNP70,CDK2,IPO4 |
| 5.174e-03 | -5.26 | Hedgehog 'on' state | REACTOME pathways | R-HSA-5632684 | 86 | 24 | 10287 | 1696 |
ULK3,PSMA8,RBX1,PSMB7,CUL3,PSMA1,CSNK1A1,PSMD9,PSMB9,CDC73,PSMB3,PSMC4,EVC2,PSMD2,PSMA6,PSMD1,GRK2,RPS27A,PSMD8,PSMD3,ARRB2,SMURF1,PSMC1,NUMB |
| 5.175e-03 | -5.26 | GO_WNT_SIGNALING_PATHWAY | MSigDB lists | GO_WNT_SIGNALING_PATHWAY | 333 | 68 | 17377 | 2626 |
ZBED3,CYLD,RAC1,XIAP,CUL1,CSNK2A1,CALM2,PSMD1,PSMA6,CDC42,AP2B1,DVL2,USP34,CELSR2,PSMA8,RBX1,CUL3,PSMB7,FRAT2,LRP5,SOX4,PSMB9,CXXC4,PAF1,HHEX,RPS27A,PSMD8,AXIN1,PSMD3,STK11,DVL1,ARRB2,SMURF1,PSMC1,AP2S1,CSNK1D,PRKAA1,NKD2,ZNRF3,PPP3CB,PSMD9,PSEN1,CSNK1A1,CDC73,SCYL2,FZD6,PSMD2,PTEN,AXIN2,BRD7,CTR9,ZRANB1,CSNK1G3,CSNK1G2,PPP3CA,RHOA,LDB1,PSMA1,RTF1,MACF1,MARK2,PSMB3,PSMC4,CSNK1G1,WNT5B,PPP3R1,VPS29,DDB1 |
| 5.181e-03 | -5.26 | MAP1LC3B (microtubule associated protein 1 light chain 3 beta) | protein interactions | 81631 | 92 | 25 | 17029 | 2761 |
ADD1,CUL3,MYBL2,GORASP2,ADRB2,OPTN,ATG4A,KEAP1,PSMA6,TBC1D17,KLHL5,ATG3,SAFB,DBI,KBTBD7,PML,RPLP1,HADHB,UPF2,ATG13,NIPSNAP2,LUC7L2,DCTN1,TMEM160,NIPSNAP1 |
| 5.181e-03 | -5.26 | GARS (glycyl-tRNA synthetase) | protein interactions | 2617 | 92 | 25 | 17029 | 2761 |
UNK,STAU1,CELSR2,HARS,GORASP2,BRCA1,XPO7,NDRG3,TARS,NPLOC4,CAND1,EPRS,HSPBP1,IARS,CORO1C,QARS,PPM1G,KHSRP,CRY2,USP11,CDK2,NMD3,MTPN,POC5,EEF1D |
| 5.189e-03 | -5.26 | GSE30971_2H_VS_4H_LPS_STIM_MACROPHAGE_WBP7_HET_UP | MSigDB lists | GSE30971_2H_VS_4H_LPS_STIM_MACROPHAGE_WBP7_HET_UP | 161 | 37 | 17377 | 2626 |
GNPNAT1,MDH2,SLC2A1,MRPS26,NDUFA4,FAM136A,PMVK,SDHA,NUP205,ZNF696,C14orf119,RPA2,DDX56,EXOSC7,EIF4A3,ANAPC7,RNF135,ERI3,CNPY3,SLC12A2,DNMT1,TIMM8B,FOPNL,MFNG,FBXO9,ABHD11,MACF1,PON2,CDKN2AIPNL,SERF2,LSM6,MPV17,WDR7,GPI,RBPJ,COPS6,CHID1 |
| 5.190e-03 | -5.26 | response to gamma radiation | biological process | GO:0010332 | 54 | 16 | 17256 | 2622 |
BAK1,PRKDC,PRKAA1,TMEM109,BCL2L1,ELK1,MEN1,XRCC5,MDM2,TIGAR,XRCC2,H2AFX,PML,BCL2,CHEK2,HRAS |
| 5.197e-03 | -5.26 | CACTGTG,MIR-128A,MIR-128B | MSigDB lists | CACTGTG,MIR-128A,MIR-128B | 316 | 65 | 17377 | 2626 |
RORB,UBE2E2,KIAA0232,WDTC1,SLC39A13,PLAGL2,UBE2Z,DAZAP2,MAPK14,ZADH2,GNB2,PAIP2,CRKL,MTMR4,PPME1,SOCS6,CABLES2,GCC1,CTDSP2,DVL2,RLIM,RYBP,SHOC2,KAT7,BTG2,E2F3,SREK1,MIER2,PDHX,SEC61A1,SPATA2,CORO1C,AXIN1,PTER,RNF38,H3F3A,TSTD2,NXT2,STRN4,LETMD1,MED13L,DCUN1D4,ARID1B,XPR1,EIF2S2,RIMS3,TNPO3,DCP1A,GLTP,CITED2,TMX1,PDPK1,AMD1,ARID1A,ARMC8,PHF6,TFEB,MOSPD3,UPF1,CCDC6,ELMO1,MAPK6,PPP1R11,FAM126A,CNOT6 |
| 5.199e-03 | -5.26 | CCR4-NOT complex | cellular component | GO:0030014 | 16 | 7 | 18223 | 2701 |
CNOT9,CNOT6,CNOT6L,CNOT11,PATL1,TOB1,CNOT3 |
| 5.208e-03 | -5.26 | KYNG_DNA_DAMAGE_DN | MSigDB lists | KYNG_DNA_DAMAGE_DN | 188 | 42 | 17377 | 2626 |
CCNC,PRKAB1,NDUFB6,RAB11B,HEXB,AGPAT1,FLOT1,TIA1,CTCF,CYCS,POMP,RAB6A,SLC35B1,ARF1,CCNL2,CSNK1A1,PRKACA,ITGB5,COPB2,CSDE1,HNRNPA2B1,PCNA,CCNA2,ITGB8,SGCB,PPA1,ALDH9A1,SNX8,EIF3L,PTPN18,RHOBTB3,NET1,RAB7A,DNAJA1,RHOB,PPP2CA,GOLGA4,GALNT2,RBL1,ITGB1,CAB39,OAZ1 |
| 5.208e-03 | -5.26 | GSE12003_MIR223_KO_VS_WT_BM_PROGENITOR_4D_CULTURE_UP | MSigDB lists | GSE12003_MIR223_KO_VS_WT_BM_PROGENITOR_4D_CULTURE_UP | 188 | 42 | 17377 | 2626 |
SLC30A9,TCF12,TMED7,LZTR1,FAM208B,MUM1,CDK2AP2,TRIO,CBLL1,SMC6,METTL3,RAPGEF6,FAM8A1,BCAP31,RNF103,HNRNPA2B1,PRKD3,ADCY9,ZNF326,SLC27A4,TTC3,CHTOP,SMC4,RBM15B,USP34,CDC37,SP3,YTHDC1,FAM118B,KAT7,ITM2A,BICD2,ASB13,SOX4,BRWD1,TMEM168,JAK1,MAGT1,PARG,GLG1,PRPF4B,FUBP1 |
| 5.208e-03 | -5.26 | GSE7852_LN_VS_THYMUS_TREG_DN | MSigDB lists | GSE7852_LN_VS_THYMUS_TREG_DN | 188 | 42 | 17377 | 2626 |
CMAS,C19orf53,HNRNPAB,PCBP1,MXD1,KIFC1,PPP1R3B,PCNA,SMC3,FUT8,RAB4A,PDS5B,H2AFY,KIFAP3,FYTTD1,CCT2,LDHA,LACTB,EZR,FRAT2,SLBP,FAM133B,NUSAP1,CADM1,CDC23,PRKRA,SOX4,ICMT,TOLLIP,PDE3B,ASF1B,SUPT16H,PTPRF,NAP1L1,NSF,CERS6,PTER,MEGF9,KPNA2,RNF14,PGAM1,RAD51D |
| 5.208e-03 | -5.26 | GSE34205_HEALTHY_VS_FLU_INF_INFANT_PBMC_DN | MSigDB lists | GSE34205_HEALTHY_VS_FLU_INF_INFANT_PBMC_DN | 188 | 42 | 17377 | 2626 |
RHOG,PARP12,AGRN,RAC1,KLHL18,MAP1LC3B,TFRC,FERMT3,CALM2,CCNK,CAPN2,C18orf32,PELO,ZNF326,PRC1,S100A6,FTL,NXT1,RBX1,CREG1,PSPC1,LDHA,SLBP,EXOSC9,LY6E,RAB1A,PATL1,SH3GLB1,RHEB,ISG15,ARF4,MASTL,DOT1L,FAS,HMGN2,CDCA4,MTHFD2,CDCA5,COX8A,HMGB2,E2F2,PGAM1 |
| 5.208e-03 | -5.26 | GSE3982_BASOPHIL_VS_TH1_DN | MSigDB lists | GSE3982_BASOPHIL_VS_TH1_DN | 188 | 42 | 17377 | 2626 |
PPP1R2,NQO1,MRPS15,CAST,MRPL39,HMGXB3,B4GALT5,OLA1,TMEM97,RRM1,TMED3,BLM,STMN1,SPAG5,SAC3D1,IARS,XRCC2,ARL6IP1,MSH2,AKR1B1,MRPL11,ALDH18A1,MYO5A,CDC37,PRPF19,PPIF,EIF5A,NASP,MKLN1,CDC123,ACSL3,ABCF2,ILF3,DNAJC9,PPFIA3,TOMM40,PSMC4,DDOST,CHEK2,YWHAH,MRPL13,NRBP1 |
| 5.208e-03 | -5.26 | GSE12845_IGD_POS_BLOOD_VS_PRE_GC_TONSIL_BCELL_UP | MSigDB lists | GSE12845_IGD_POS_BLOOD_VS_PRE_GC_TONSIL_BCELL_UP | 188 | 42 | 17377 | 2626 |
GLT8D1,GORASP1,DHPS,ABCC10,SNX15,UBE2Z,SLC4A2,NENF,ZNF428,CAPN2,CLUAP1,PDK2,DBNDD1,PRDM4,GPATCH1,FEM1B,TAGLN2,CNPY3,CSNK1G3,HTRA2,NAGPA,HMGN4,SNX2,BAZ2A,C16orf72,KIAA0040,RPL38,CBFA2T2,TSR2,RHOB,ZMYM3,NSA2,MAN2A2,SH3BP5,ANKZF1,HLA-B,NUCB1,TULP3,RPS14,TATDN2,SMARCD1,PTOV1 |
| 5.208e-03 | -5.26 | GSE5589_LPS_VS_LPS_AND_IL10_STIM_IL10_KO_MACROPHAGE_180MIN_DN | MSigDB lists | GSE5589_LPS_VS_LPS_AND_IL10_STIM_IL10_KO_MACROPHAGE_180MIN_DN | 188 | 42 | 17377 | 2626 |
WASF2,LIME1,CYLD,TM9SF4,WDYHV1,SNX15,DLGAP4,KCTD17,SPR,RAB11A,POFUT1,APP,LRRC14,ATIC,MBD2,FEM1B,CLDND1,FAM76B,UBE2M,ABCC1,NAGPA,PLK1,TGFB1,TIMP2,GNG7,UBE2V1,ARHGAP15,ARF4,SUPT16H,NUCB1,TBC1D17,SMAD2,ETS2,LIMK1,SIL1,FAM122A,SPCS3,DNAJC30,ZSWIM3,RNF14,PFKP,DEF6 |
| 5.208e-03 | -5.26 | GSE20727_DNFB_ALLERGEN_VS_ROS_INH_AND_DNFB_ALLERGEN_TREATED_DC_DN | MSigDB lists | GSE20727_DNFB_ALLERGEN_VS_ROS_INH_AND_DNFB_ALLERGEN_TREATED_DC_DN | 188 | 42 | 17377 | 2626 |
LIME1,MCM10,FOXM1,SRGN,GNE,PXMP2,KIF2C,POMP,SRXN1,PRNP,DTL,RPA2,SIVA1,SRI,MRPL34,EI24,GTSE1,MRPL54,AHCY,LMAN1,SYTL3,GINS1,MND1,NEK7,ERLIN1,PBK,CDC6,NUSAP1,NFATC2,BRCA1,CCNF,SHCBP1,BORA,FAS,UBXN2B,COX8A,PML,ATF6,GEN1,TSPAN5,SSSCA1,FAM72A |
| 5.210e-03 | -5.26 | GO_ENDOPLASMIC_RETICULUM_GOLGI_INTERMEDIATE_COMPARTMENT_MEMBRANE | MSigDB lists | GO_ENDOPLASMIC_RETICULUM_GOLGI_INTERMEDIATE_COMPARTMENT_MEMBRANE | 59 | 17 | 17377 | 2626 |
CD59,TMED7,SURF4,GOLGA2,TMED10,VMP1,GORASP1,ERGIC3,PIEZO1,TMED3,MCFD2,SLC35C2,LMAN1,BCAP31,TMED2,CSNK1D,KDELR1 |
| 5.210e-03 | -5.26 | GO_HISTONE_DEACETYLASE_COMPLEX | MSigDB lists | GO_HISTONE_DEACETYLASE_COMPLEX | 59 | 17 | 17377 | 2626 |
NCOR2,TRERF1,MTA2,CSNK2A1,TAF6L,MBD3,APPL1,BRMS1,SAP130,HINT1,CHD3,HDAC7,MBD2,APPL2,RBBP4,HDAC2,SAP30 |
| 5.231e-03 | -5.25 | regulation of protein kinase activity | biological process | GO:0045859 | 800 | 148 | 17256 | 2622 |
CCNC,FGFR1OP,TXN,TSC2,MAP3K7CL,NF1,CCNL2,CCNB1,S1PR2,MAPK14,PARK7,PRNP,CDK5,CALM2,CDKN2C,RAP1A,CDC25B,MLST8,CDC37,PLK1,COPS8,BAK1,NCK1,GMFB,MRNIP,CDC6,UBE2V1,LRP5,MAP3K4,HHEX,RPS27A,AXIN1,SOCS4,CAB39,ADAM9,STK11,CLU,DVL1,PDCD4,HSPH1,CLSPN,GMFG,GADD45G,PRKAA1,LAMTOR3,CIB1,RGS2,PSEN1,VPS25,TFAP4,RB1,FBXO7,MDFIC,MVP,GNAI2,SOCS5,MAPKAPK3,GTPBP4,GBA,KRAS,MAP4K3,ADRB2,MAP2K2,XRCC5,TSC1,MBIP,DUSP3,CSK,QARS,NUP62,MAP3K5,ALS2,CDKN2A,BCCIP,KARS,GGNBP2,TRAF7,RAF1,MAGED1,TPX2,DAZAP2,PRKACA,DUSP22,LYN,APP,CRKL,SHC1,RALB,KIF14,ADCY9,SOCS6,CDKN1B,F2R,ABI1,CDK12,DVL2,CHP1,ADCY7,PSRC1,TAOK1,MAP4K4,ELP4,DNAJA1,PKMYT1,SOCS7,PPP2CA,TAB2,STK38,CORO1C,GADD45B,RPLP1,MAPK1,LRP8,MIF,ZFP91,AKT1S1,BLM,PTPN2,CCNK,PDCD10,PTEN,PTPN11,DUS2,H2AFY,ATG13,MAP3K14,TGFB1,PDPK1,TELO2,RHOA,ADAM17,TNFAIP3,PRKAR1B,JTB,MEN1,MARK2,MAPK3,SH3BP5,NEK1,HGS,GPS2,OSBPL8,PKD2,NR2F2,CD81,HIPK3,HRAS,FAF1 |
| 5.232e-03 | -5.25 | FAM189A2 (family with sequence similarity 189 member A2) | protein interactions | 9413 | 78 | 22 | 17029 | 2761 |
ANKRD13D,ABCA3,UBXN1,TYW1,AGPAT3,SLC12A9,PDE3B,FAM8A1,RHBDD1,RHBDF2,OPTN,TMEM179B,WWP2,HERC3,KLHL20,UPK3BL1,YWHAZ,CLDND1,TRIM32,SLC26A2,SLC12A2,CHPT1 |
| 5.257e-03 | -5.25 | regulation of establishment of protein localization to mitochondrion | biological process | GO:1903747 | 78 | 21 | 17256 | 2622 |
UBE2D3,HSPH1,ATP5IF1,DYNLL1,PRKAA1,DNAJA1,SH3GLB1,USP36,HUWE1,TFDP1,PPP3R1,E2F1,PARL,BCL2,ATG13,YWHAZ,TP53BP2,TFDP2,LMAN1,YWHAH,HTRA2 |
| 5.258e-03 | -5.25 | positive regulation of telomerase activity | biological process | GO:0051973 | 36 | 12 | 17256 | 2622 |
HNRNPA2B1,MAP3K4,CCT2,NVL,NEK7,AURKB,PTGES3,MAPK1,PARN,POT1,XRCC5,MAPK3 |
| 5.258e-03 | -5.25 | transcription initiation from RNA polymerase I promoter | biological process | GO:0006361 | 36 | 12 | 17256 | 2622 |
UBTF,RRN3,POLR2L,CD3EAP,POLR2K,BAZ2A,SMARCA4,POLR1B,GTF2H2,ZNRD1,TWISTNB,MAPK3 |
| 5.260e-03 | -5.25 | THIOREDOXIN_1 | prosite domains | PS00194 | 17 | 7 | 12060 | 1670 |
TXNL1,DNAJC10,TXN,PDIA6,TMX4,TMX1,TMX3 |
| 5.284e-03 | -5.24 | cytosolic large ribosomal subunit | cellular component | GO:0022625 | 65 | 18 | 18223 | 2701 |
RPL29,RPL35,RPLP2,RPL6,RPL38,RPL8,RPL15,RPL27A,RPL23A,RPL36,RPL11,GEMIN5,RPL37,RPL32,RPL17,RPLP1,RPL19,RPL22L1 |
| 5.285e-03 | -5.24 | IQCB1 (IQ motif containing B1) | protein interactions | 9657 | 222 | 51 | 17029 | 2761 |
RAB14,MAPRE1,NUP188,DYNLL1,RAF1,RAC1,MYH9,CDIPT,TWF2,SEC16A,CALM2,HNRNPA2B1,PSMA6,DPYSL2,RAB35,RRBP1,PTPN11,HADHB,LTN1,YBX1,UBE3B,GEMIN4,RNF135,EIF5A,GUK1,PRKDC,HNRNPF,PSMB7,PSMA1,MRPL16,UBE2V1,DNAJA1,PKM,RAB1A,PSMB3,PRDX1,ECH1,NAP1L1,CDC16,PCM1,ATP1A1,EXOC4,PPP3R1,CAB39,MDH1,ACTB,DTD1,ATP5F1A,PGAM1,NUDT3,TUBB |
| 5.289e-03 | -5.24 | cellular response to organic substance | biological process | GO:0071310 | 2310 | 393 | 17256 | 2622 |
RAB14,MAX,H2AFZ,ADD1,CXXC1,CUL1,CCNB1,PARK7,EEF2K,CDK5,USF1,PSMD1,DNM2,TRA2B,TIPARP,DNMT1,CDC5L,BAK1,KLF10,GABPA,AKT2,GNG7,HNRNPF,MCL1,MCM2,SLC25A5,SMAD2,WAS,RPS27A,PSMD8,PTPN7,ITGB1,ATP6V0C,RNASEL,SMAD1,ARRB2,HDAC2,PFKP,PDCD4,SLC25A33,DDX58,HSPH1,SEC61G,POLR2K,HLA-E,PRKAA1,DHX9,ITGB5,PSEN1,PSMD9,METTL3,CDC73,LMNA,CFLAR,TFAP4,FKBP1A,RNF121,PDXP,MEGF8,DAPK1,ATP6V0A2,MYDGF,GNAI2,SOCS5,CYFIP1,ETV3,ERO1A,MYBL2,USP10,BCLAF1,SRSF5,ADRB2,ARID1A,PKM,ELK1,KDM3A,PSMB3,TWISTNB,FAS,XRCC5,DERL1,SEC31A,CAT,EPRS,FNTA,POLR2J,CSK,RBMX,PIAS2,SMPD4,MAP3K5,YY1,RNF14,KARS,ATXN3,DNMT3A,RWDD1,RAB11B,UBR2,RAF1,ACTR3,WDTC1,BCL2L1,PRKACA,CPNE3,APP,GNB2,CRKL,CCNA2,SHC1,SP100,RALB,MTMR4,ADCY9,SOCS6,CDKN1B,MAVS,TALDO1,CFL1,DCTN1,ADCY7,ATP6V1G1,SHOC2,SEC61B,POLR2L,WBP2,POLR2D,CUL3,ATP6V0A1,DNAJA1,SHCBP1,PSMB9,SERP1,MAT2A,DDX17,SOCS7,ANKZF1,HSPA4,SEC61A1,JAK1,VPS26B,DGCR8,SAFB,HIPK2,STAT1,ATF6,TICAM1,LRP8,DYNC1LI2,CSNK1D,LRCH1,ADAM23,POU3F2,TWNK,FLOT1,MYNN,AKT1S1,SDF2L1,IP6K2,BLM,IL21R,FOXO3,HLA-A,TUT4,GTF2F1,CAPN2,PSMD2,PDCD10,PTEN,FUT8,PTPN11,CNN2,MAP3K14,CREB1,UBE2M,NCOA2,HNRNPM,PDPK1,PPP3CA,TNFAIP3,KAT2A,DENND4C,RPL8,KCNQ1,PDE3B,POLR2A,YIF1A,KIF18A,KEAP1,LTBP4,TATDN2,WNT5B,MAPK6,PML,KHSRP,HMGB2,DDX5,ASNA1,PSAP,YWHAH,CPEB2,FAM83G,SRM,RORB,AGRN,PTP4A3,SLC29A1,SIRT2,MAPK14,BECN1,BIRC2,BCAT2,SSR1,PRNP,ABL2,RAB8A,RAP1A,CDC42,EIF4A3,RAB35,IL6ST,PIK3R2,TXLNA,AKR1B1,ZFYVE27,CARM1,PTPRK,LARS,PTPN18,TRIM8,RBX1,EZR,UBE2V1,CDC6,IL12RB1,BRCA1,SOX4,PRKRA,MPC1,OPTN,DPYSL3,PAF1,BRWD1,SOCS4,PQBP1,ADAM9,ACTB,CHEK2,ATP6V0E1,C2CD5,PSMC1,UBE2D3,PHB2,AGTRAP,CIB1,CDIP1,LAMTOR3,TIA1,THRAP3,ARID1B,SRRT,RHBDD1,RB1,NUS1,MBD2,CAPZA1,CTR9,TIMELESS,BCL2,ATP6V0D1,PREB,ABHD2,POLR2I,AACS,GBA,PSMA1,KRAS,SYVN1,APPL1,ISG15,IRF5,DAPK3,PSMC4,RXRB,SYNCRIP,NSMF,KLHL15,NFIL3,LAMTOR4,SLC16A1,PITPNA,NUP62,YWHAZ,RUVBL2,SNRNP70,EHD4,HNRNPDL,TOB1,ADNP2,SMARCD1,GNPNAT1,RRAGC,SMARCA4,IRF3,ATP6V1B2,DUSP22,TWF2,LYN,HNRNPA2B1,VAV1,PDK2,ATP6V0B,UBXN2A,MDM2,PSMA6,AKAP8,CORO1A,AHCYL1,PDIA6,CTDSP2,SPIDR,HTRA2,POLR2G,BIRC3,CGAS,PSMA8,SELPLG,SLC26A6,PSMB7,ERBIN,EDEM2,TOLLIP,ATP1A1,IDE,TAB2,PSMD3,STAT6,SCARB1,NCOA1,SMURF1,MAPK1,SMAD4,ABCA1,PARD3,MIF,GCLM,CASP6,RAE1,AGO2,ARF1,AP3S1,TFRC,DNAJB9,PTPN2,KIF5B,FGFR3,IRF4,CTSS,GRK2,TANK,ARHGEF2,STAT3,CAMK2G,RNF5,MYO5A,TGFB1,PAQR6,PPP1R9B,ADAM17,RHOA,PRKDC,PRKAR1B,RANGAP1,MEN1,HSPA1B,MAPK3,CNOT9,CTSL,HLA-B,CACNB1,ATP6V1D,UPF1,TRIM26,PLAA,BIRC5,TWSG1,ZC3H7B,E2F1,PKD2,SRSF3,PLOD3,ATP6V1C1,NR2F2 |
| 5.292e-03 | -5.24 | BCL2FAMILY | prints domains | PR01862 | 8 | 4 | 4652 | 473 |
BAK1,BCL2,MCL1,BCL2L1 |
| 5.314e-03 | -5.24 | Kinesin_motor_CS | interpro domains | IPR019821 | 41 | 13 | 18492 | 2768 |
KIF5B,KIF2A,KIFC1,STARD9,KIF3B,KIF18A,KIF18B,KIF14,KIF13B,KIF23,KIF22,KIF2C,KIF11 |
| 5.316e-03 | -5.24 | flank | COSMIC cancer mutations | flank | 16 | 7 | 17385 | 2587 |
FGFR3,KRAS,NRAS,PTEN,HRAS,CDKN2A,PTPN11 |
| 5.321e-03 | -5.24 | purine ribonucleoside triphosphate biosynthetic process | biological process | GO:0009206 | 83 | 22 | 17256 | 2622 |
TGFB1,GALK1,COX5B,LDHA,ATP6V0A1,OGDH,ATP5F1B,ADPGK,PKM,ATP5MF,ATP5PF,STOML2,ATP5MC3,IMPDH1,ATP6V0A2,DHTKD1,CYC1,ATP5F1A,GPI,NIPSNAP2,PGAM1,PFKP |
| 5.321e-03 | -5.24 | retrograde transport, endosome to Golgi | biological process | GO:0042147 | 83 | 22 | 17256 | 2622 |
SNX8,GCC2,RHOBTB3,SNX2,RAB7A,VTI1A,ZFYVE21,RAB6A,GOSR1,STX16,ERC1,RIC1,HEATR5B,TBC1D17,SURF4,VPS26B,TBC1D14,AP1S1,LMAN1,PIKFYVE,VPS29,DCTN1 |
| 5.325e-03 | -5.24 | H3F3B (H3 histone family member 3B) | protein interactions | 3021 | 34 | 12 | 17029 | 2761 |
UNK,NASP,MCM5,SMARCA4,FUS,MCM2,PARP10,CD81,CHD1,CARM1,ASF1B,SUPT16H |
| 5.325e-03 | -5.24 | ARRDC1 (arrestin domain containing 1) | protein interactions | 92714 | 34 | 12 | 17029 | 2761 |
PDCD6IP,ABRAXAS2,PBK,KCTD17,EPN1,RCOR1,ADRB2,NCAPG,RCOR3,WDR45B,APP,WWP2 |
| 5.325e-03 | -5.24 | Cct8 (chaperonin containing Tcp1, subunit 8 (theta)) | protein interactions | 12469 | 34 | 12 | 17029 | 2761 |
DTL,RFWD3,CCT2,SLC2A1,PPP6C,ACTB,NCLN,DHX15,PDCL3,TUBB,MLST8,CSTF1 |
| 5.325e-03 | -5.24 | ZC3HC1 (zinc finger C3HC-type containing 1) | protein interactions | 51530 | 34 | 12 | 17029 | 2761 |
PDPK1,PLK1,RBX1,RPL38,CUL1,CCNB1,EHD4,SASS6,MAPK1,APP,MAPK3,CDC5L |
| 5.325e-03 | -5.24 | Tor1aip1 (torsin A interacting protein 1) | protein interactions | 208263 | 34 | 12 | 17029 | 2761 |
CYFIP1,SNUPN,GOLIM4,GALNT2,SCAMP3,TIMM23,TOR1AIP1,DNM2,LTN1,SMARCA4,ORC3,PRDX1 |
| 5.325e-03 | -5.24 | PPP4R1 (protein phosphatase 4 regulatory subunit 1) | protein interactions | 9989 | 34 | 12 | 17029 | 2761 |
PPP2CA,SEC61A1,NDUFB4,HNRNPR,CCDC6,MTA2,MAP4,CEP63,AQR,POLR2A,SPTAN1,LDHB |
| 5.326e-03 | -5.24 | nonhomologous end joining complex | cellular component | GO:0070419 | 9 | 5 | 18223 | 2701 |
PAXX,DCLRE1C,XRCC4,PRKDC,XRCC5 |
| 5.326e-03 | -5.24 | replication fork protection complex | cellular component | GO:0031298 | 9 | 5 | 18223 | 2701 |
TIMELESS,WDHD1,MCM10,TOP1MT,GINS4 |
| 5.326e-03 | -5.24 | SCAR complex | cellular component | GO:0031209 | 9 | 5 | 18223 | 2701 |
WASF2,CYFIP1,NCKAP1,CYFIP2,ABI1 |
| 5.327e-03 | -5.24 | Aryl Hydrocarbon Receptor | WikiPathways | WP2586 | 48 | 15 | 5312 | 837 |
RB1,NCOR2,PSRC1,NRAS,NQO1,NF1,RAF1,E2F1,CDKN1B,KRAS,MAPK1,CDK2,KLF6,HRAS,CDC37 |
| 5.327e-03 | -5.24 | transforming growth factor beta receptor signaling pathway | biological process | GO:0007179 | 98 | 25 | 17256 | 2622 |
TGFB1,RHOA,KLF10,DUSP22,ITGB5,FKBP1A,FNTA,SMAD2,LTBP4,RPS27A,MTMR4,TWSG1,HIPK2,FUT8,PML,ITGB1,ADAM9,SMAD1,CREB1,SMURF1,ARRB2,UBE2M,SMAD4,PARD3,PTPRK |
| 5.332e-03 | -5.23 | GSE10325_BCELL_VS_MYELOID_UP | MSigDB lists | GSE10325_BCELL_VS_MYELOID_UP | 172 | 39 | 17377 | 2626 |
ADD1,TCF3,MAGED1,ACAP1,GTF3A,GGA2,PPP1R16B,RPA2,IARS,ATIC,AKR1B1,BCL2,FBL,MICAL3,HTRA2,PTPRK,POU2AF1,NXT1,RPL35,BIRC3,KIAA0040,GNG7,RPL6,EZR,ESYT1,EAF2,MCM2,MEN1,ODC1,RPSA,RPL36,PRIM1,OPTN,PDLIM1,EIF2D,FAM3C,QRSL1,TRAF5,CD81 |
| 5.335e-03 | -5.23 | regulation of protein binding | biological process | GO:0043393 | 209 | 46 | 17256 | 2622 |
MAPRE1,CYLD,ADD1,DNAJB2,FLOT1,PRKACA,STMN1,PSEN1,PARK7,APP,GTF2F1,RPL11,CDK5,FKBP1A,RALB,PIN1,GTSE1,BCL2,PLCL2,CARM1,PLK1,BAK1,MFNG,ADRB2,AURKB,MEN1,SYMPK,BTBD1,KRIT1,MAPK3,EPB41,DERL1,PTPRF,PPP2CA,GOLGA2,HIPK2,MIA2,PRMT7,ACTB,TICAM1,RUVBL2,ROCK1,DVL1,ARRB2,NMD3,SNAPIN |
| 5.338e-03 | -5.23 | FBXW4 (F-box and WD repeat domain containing 4) | protein interactions | 6468 | 51 | 16 | 17029 | 2761 |
COPS8,CCT2,PFDN5,HNRNPR,PDRG1,DHX9,CUL1,DDX5,COPS7B,COPS6,YWHAH,CCT8,NUP205,PDCL3,DCTN1,CDC37 |
| 5.338e-03 | -5.23 | RRM2 (ribonucleotide reductase regulatory subunit M2) | protein interactions | 6241 | 51 | 16 | 17029 | 2761 |
PLK1,ARID2,VHL,PRKDC,POC1A,DNAAF5,RRM1,CCNF,NPLOC4,PCM1,CDC27,RBMX,MAPK1,CDKN2A,ANAPC4,CSTF1 |
| 5.338e-03 | -5.23 | FAM120A (family with sequence similarity 120A) | protein interactions | 23196 | 51 | 16 | 17029 | 2761 |
STAU1,RBM42,GSPT2,CUL3,BRCA1,SEC16A,GGPS1,MATR3,CAND1,MRPL50,SYNCRIP,RBMX,ZNF746,TARDBP,RBM3,SSSCA1 |
| 5.338e-03 | -5.23 | SDCCAG3 (serologically defined colon cancer antigen 3) | protein interactions | 10807 | 51 | 16 | 17029 | 2761 |
ASPM,APP,ANKRD28,PCM1,CCNA2,VPS26B,CCDC14,CHD3,CENPJ,ODF2,AP1M1,ZFYVE27,GTSE1,SMURF1,SASS6,EYA2 |
| 5.338e-03 | -5.23 | CKS1B (CDC28 protein kinase regulatory subunit 1B) | protein interactions | 1163 | 51 | 16 | 17029 | 2761 |
CDT1,ARID5A,XIAP,CUL1,PKMYT1,CCNB1,PSMD9,CCNA2,CDC27,CDKN1B,COPS6,CCNB2,ECPAS,CDK2,CDC37,LDHB |
| 5.338e-03 | -5.23 | Ndc80 (NDC80 kinetochore complex component) | protein interactions | 67052 | 51 | 16 | 17029 | 2761 |
ASPM,ZNF768,NUF2,THRAP3,BICD2,MACF1,MIS12,CENPU,PCM1,DSN1,SNAP29,RRBP1,PRDX5,ODF2,SGF29,SNAPIN |
| 5.338e-03 | -5.23 | GRPEL1 (GrpE like 1, mitochondrial) | protein interactions | 80273 | 51 | 16 | 17029 | 2761 |
HSPH1,EYA1,MDH2,WBP2,BRCA1,DNAJB1,STMN1,RPA1,HSPA4,AHNAK,DUT,ATF2,TERF1,RPRD1B,CCAR1,FUBP1 |
| 5.341e-03 | -5.23 | KIF11 (kinesin family member 11) | protein interactions | 3832 | 126 | 32 | 17029 | 2761 |
CYLD,LUZP1,ANK3,SNRPD3,RPL23A,DECR1,RPAP1,TACC3,DCTN1,MLST8,SRPK2,CDC5L,ANKLE2,ACSL5,TNFAIP3,ACSL3,GTPBP4,LDHA,BRCA1,KIF11,EIF3A,PI4K2A,RPL32,DGCR8,MAP4,MRPL27,FAM122A,YWHAZ,DUSP11,H3F3A,SNRNP70,SMURF1 |
| 5.341e-03 | -5.23 | Immt (inner membrane protein, mitochondrial) | protein interactions | 76614 | 26 | 10 | 17029 | 2761 |
ANKLE2,EXOC3,DECR1,PCM1,TNPO3,DHTKD1,TICAM1,FBXL19,GOSR1,MAT2A |
| 5.341e-03 | -5.23 | SNX12 (sorting nexin 12) | protein interactions | 29934 | 26 | 10 | 17029 | 2761 |
HGS,PIN1,PPM1G,ARL6IP1,TAGLN2,AHCYL1,IGBP1,PSMC1,CLNS1A,CDC5L |
| 5.341e-03 | -5.23 | RSL24D1 (ribosomal L24 domain containing 1) | protein interactions | 51187 | 26 | 10 | 17029 | 2761 |
NSA2,PPAN,EWSR1,LSM8,FBL,CDC23,MCPH1,MAK16,IFI16,CAND1 |
| 5.341e-03 | -5.23 | PATL1 (PAT1 homolog 1, processing body mRNA decay factor) | protein interactions | 219988 | 26 | 10 | 17029 | 2761 |
SART1,GOLGA2,LSM6,MYO18A,DCP1A,TARDBP,PRPF4,PRPF3,APP,CDC37 |
| 5.341e-03 | -5.23 | BTBD9 (BTB domain containing 9) | protein interactions | 114781 | 26 | 10 | 17029 | 2761 |
VPS26B,PPP1R21,UBXN1,EXOSC1,RAD23B,CUL3,COPS6,PDIA6,FAF1,ATP6V1G1 |
| 5.341e-03 | -5.23 | ZFP91 (ZFP91 zinc finger protein) | protein interactions | 80829 | 26 | 10 | 17029 | 2761 |
UTP20,FTSJ1,GBA,CTR9,MAP3K14,FBL,LUC7L,CDKN2A,SRPK2,USP5 |
| 5.341e-03 | -5.23 | POLE3 (DNA polymerase epsilon 3, accessory subunit) | protein interactions | 54107 | 26 | 10 | 17029 | 2761 |
USO1,ATAD2,POLE,ANXA6,DRAP1,TOP2B,ORC1,NANS,APP,XRCC5 |
| 5.341e-03 | -5.23 | TMED4 (transmembrane p24 trafficking protein 4) | protein interactions | 222068 | 26 | 10 | 17029 | 2761 |
TMED10,NAGLU,GORASP2,TMED3,IKBIP,LMAN1,ECPAS,SPPL2B,CHCHD6,TMED2 |
| 5.341e-03 | -5.23 | GCC2 (GRIP and coiled-coil domain containing 2) | protein interactions | 9648 | 26 | 10 | 17029 | 2761 |
EXOC3,GCC2,DHX16,KIFAP3,PKD2,TTC4,PMF1,ZRANB1,SRPK2,RAD23A |
| 5.341e-03 | -5.23 | COMMD10 (COMM domain containing 10) | protein interactions | 51397 | 26 | 10 | 17029 | 2761 |
CCDC93,TP53RK,VPS26C,TRAF7,TCTEX1D2,COMMD5,COMMD4,COMMD6,COMMD8,VPS29 |
| 5.341e-03 | -5.23 | IGHM (immunoglobulin heavy constant mu) | protein interactions | 3507 | 26 | 10 | 17029 | 2761 |
SNX27,UBQLN4,TK1,EWSR1,MAPKAPK3,SEL1L,DDX31,SYVN1,PATL1,APP |
| 5.350e-03 | -5.23 | Degradation of DVL | REACTOME pathways | R-HSA-4641258 | 59 | 18 | 10287 | 1696 |
PSMA8,RBX1,PSMB7,CUL3,PSMA1,PSMB9,PSMD9,PSMB3,PSMC4,PSMD2,PSMA6,PSMD1,RPS27A,PSMD3,PSMD8,DVL1,PSMC1,DVL2 |
| 5.350e-03 | -5.23 | regulation of coenzyme metabolic process | biological process | GO:0051196 | 88 | 23 | 17256 | 2622 |
NDC1,NUP188,RAE1,PRKAA1,NUP54,PFKFB3,NUP155,PDHX,NUP205,PDK2,NUP210,TIGAR,NUP107,OGT,NUP62,NUP153,ECD,STAT3,PGAM1,NUP58,NUP85,AAAS,SEH1L |
| 5.351e-03 | -5.23 | regulation of TOR signaling | biological process | GO:0032006 | 93 | 24 | 17256 | 2622 |
TELO2,LARS,TSC2,MIOS,UBR2,PRKAA1,LAMTOR3,RFFL,FBXO9,RRAGC,AKT1S1,RHEB,EPM2A,TSC1,TMEM127,GNA12,PDCD6,WDR59,LAMTOR4,ARNTL,FAM83D,STK11,SEH1L,MLST8 |
| 5.351e-03 | -5.23 | regulation of protein localization to cell periphery | biological process | GO:1904375 | 93 | 24 | 17256 | 2622 |
RHOG,PDPK1,TGFB1,GOPC,ACSL3,NKD2,CIB1,EZR,BCL2L1,RAB11A,APPL1,PICALM,SAPCD2,EPB41,PRNP,KIF5B,CDK5,PPP2R5A,CSK,CNPY4,ITGB1,VPS4A,TMBIM1,NUMB |
| 5.385e-03 | -5.22 | GSE7768_OVA_ALONE_VS_OVA_WITH_MPL_IMMUNIZED_MOUSE_WHOLE_SPLEEN_6H_DN | MSigDB lists | GSE7768_OVA_ALONE_VS_OVA_WITH_MPL_IMMUNIZED_MOUSE_WHOLE_SPLEEN_6H_DN | 156 | 36 | 17377 | 2626 |
FEZ2,MCM10,FAM53C,PTTG1,CYCS,POMP,CRLF3,MXD1,CREM,PHC2,PDCD10,TPST1,APOOL,STAT3,PPA1,DRAM2,MORC3,DCLRE1C,AZI2,ASB13,PSMB9,ISG15,ARF4,FAS,KEAP1,CERS6,SNAP29,BBX,NLRC5,TMEM219,H3F3A,EHD4,BRWD3,TRAF5,RNF14,ZC3HAV1 |
| 5.394e-03 | -5.22 | histone H3 acetylation | biological process | GO:0043966 | 45 | 14 | 17256 | 2622 |
MBIP,IRF4,KAT2A,BRPF3,KAT7,LDB1,ELP4,TAF5L,TAF12,TAF6L,WDR5,SUPT7L,SGF29,MEAF6 |
| 5.403e-03 | -5.22 | Acyltransferase | pfam domains | PF01553 | 16 | 7 | 17054 | 2545 |
AGPAT3,AGPAT2,TAZ,LCLAT1,LPCAT1,LPCAT4,AGPAT1 |
| 5.403e-03 | -5.22 | dsrm | pfam domains | PF00035 | 16 | 7 | 17054 | 2545 |
STAU1,STRBP,PRKRA,DGCR8,DUS2,ILF3,DHX9 |
| 5.409e-03 | -5.22 | CPNE5 (copine 5) | protein interactions | 57699 | 30 | 11 | 17029 | 2761 |
GEMIN5,NAPG,USO1,NCK1,MTA1,MTA2,UROD,WDHD1,BICD2,MBD3,RAD54B |
| 5.409e-03 | -5.22 | VPS37B (VPS37B, ESCRT-I subunit) | protein interactions | 79720 | 30 | 11 | 17029 | 2761 |
ERCC1,RPRD1A,QARS,PRKAA1,CEP55,YBX1,DNAJB1,XPO7,CDC73,BYSL,SMARCD1 |
| 5.409e-03 | -5.22 | MAPRE3 (microtubule associated protein RP/EB family member 3) | protein interactions | 22924 | 30 | 11 | 17029 | 2761 |
MAPRE2,MAPRE1,KIF18B,SIAH1,APPL2,PSMA1,KIF2C,AURKB,PTGES3,RAB1A,DCTN1 |
| 5.409e-03 | -5.22 | PRAM1 (PML-RARA regulated adaptor molecule 1) | protein interactions | 84106 | 30 | 11 | 17029 | 2761 |
MBD1,CCDC57,UBE2E2,NEK6,PCGF1,LYN,PSEN1,APP,MXD1,CDC37,FAS |
| 5.409e-03 | -5.22 | BCL7B (BCL tumor suppressor 7B) | protein interactions | 9275 | 30 | 11 | 17029 | 2761 |
TERF2IP,BCL7C,SMARCA4,RACGAP1,ARID1A,WDR62,SMARCE1,TERF1,ARID1B,SMARCD1,NIPSNAP1 |
| 5.409e-03 | -5.22 | BOD1L1 (biorientation of chromosomes in cell division 1 like 1) | protein interactions | 259282 | 30 | 11 | 17029 | 2761 |
MKNK1,KEAP1,CXXC1,PRDX5,VAV2,GTSE1,NSD3,WDR5,TAF6,SGF29,TACC3 |
| 5.409e-03 | -5.22 | ACAA1 (acetyl-CoA acyltransferase 1) | protein interactions | 30 | 30 | 11 | 17029 | 2761 |
SUGP1,CAT,PPIB,PEX5,SARNP,MTHFD2,TRAPPC9,NDUFA2,MRPL42,NDUFA7,CDK12 |
| 5.409e-03 | -5.22 | NOP16 (NOP16 nucleolar protein) | protein interactions | 51491 | 30 | 11 | 17029 | 2761 |
NAP1L1,MECP2,TARDBP,PRKRA,ZC3H3,APP,ZC3HAV1,IFI16,SRPK2,HP1BP3,CAND1 |
| 5.409e-03 | -5.22 | MACROD1 (MACRO domain containing 1) | protein interactions | 28992 | 30 | 11 | 17029 | 2761 |
EXOC3,PTPN7,DHX9,H2AFX,YBX1,ERC1,EPB41,SUPT16H,XRCC5,SSRP1,RPA1 |
| 5.409e-03 | -5.22 | URB1 (URB1 ribosome biogenesis 1 homolog (S. cerevisiae)) | protein interactions | 9875 | 30 | 11 | 17029 | 2761 |
ZNF512,RBM34,KIF14,MECP2,NOL8,MAPK6,CDC23,TFG,RBM4,CCDC59,IFI16 |
| 5.409e-03 | -5.22 | ARHGEF12 (Rho guanine nucleotide exchange factor 12) | protein interactions | 23365 | 30 | 11 | 17029 | 2761 |
GNA12,CYLD,RHOA,SMC3,KLHL20,RHOC,CUL3,ARHGEF12,ARRB2,ABCA1,NIPSNAP1 |
| 5.409e-03 | -5.22 | CHM (CHM, Rab escort protein 1) | protein interactions | 1121 | 30 | 11 | 17029 | 2761 |
KIF2A,RAB14,RAB18,RAB11B,RAB7A,RAB4A,RBM3,RAB6A,RAB1A,RAB5B,RAB11A |
| 5.409e-03 | -5.22 | MKRN2 (makorin ring finger protein 2) | protein interactions | 23609 | 30 | 11 | 17029 | 2761 |
NIFK,PARP12,TM9SF4,C1orf109,BRCA1,SNRNP70,NKAPD1,HNRNPDL,PAIP1,LUC7L2,PDLIM2 |
| 5.409e-03 | -5.22 | SIVA1 (SIVA1 apoptosis inducing factor) | protein interactions | 10572 | 30 | 11 | 17029 | 2761 |
ABL2,MDM2,PCNA,RAD18,XIAP,PXMP2,BCL2L1,STMN1,APP,CDKN2A,CAMK2G |
| 5.419e-03 | -5.22 | epidermal_nevus | COSMIC cancer mutations | epidermal_nevus | 9 | 5 | 17385 | 2587 |
FGFR3,KRAS,NRAS,PTEN,HRAS |
| 5.419e-03 | -5.22 | Bowen_disease | COSMIC cancer mutations | Bowen_disease | 9 | 5 | 17385 | 2587 |
FGFR3,KRAS,NRAS,HRAS,CDKN2A |
| 5.419e-03 | -5.22 | soft_tissue-fibrous_tissue_and_uncertain_origin-malignant_fibrous_histiocytoma-pleomorphic_sarcoma-storiform_pleomorphic | COSMIC cancer mutations | soft_tissue-fibrous_tissue_and_uncertain_origin-malignant_fibrous_histiocytoma-pleomorphic_sarcoma-storiform_pleomorphic | 9 | 5 | 17385 | 2587 |
RB1,KRAS,NRAS,HRAS,ETV6 |
| 5.419e-03 | -5.22 | in_situ_epithelial_neoplasm | COSMIC cancer mutations | in_situ_epithelial_neoplasm | 9 | 5 | 17385 | 2587 |
FGFR3,KRAS,NRAS,HRAS,CDKN2A |
| 5.419e-03 | -5.22 | compound | COSMIC cancer mutations | compound | 9 | 5 | 17385 | 2587 |
FGFR3,KRAS,NRAS,HRAS,CDKN2A |
| 5.419e-03 | -5.22 | upper_aerodigestive_tract-larynx-carcinoma | COSMIC cancer mutations | upper_aerodigestive_tract-larynx-carcinoma | 9 | 5 | 17385 | 2587 |
CDKN2C,KRAS,NRAS,HRAS,CDKN2A |
| 5.419e-03 | -5.22 | soft_tissue-striated_muscle-rhabdomyosarcoma-pleomorphic | COSMIC cancer mutations | soft_tissue-striated_muscle-rhabdomyosarcoma-pleomorphic | 9 | 5 | 17385 | 2587 |
KRAS,NRAS,PTEN,HRAS,CDKN2A |
| 5.419e-03 | -5.22 | haematopoietic_and_lymphoid_tissue-large_intestine-lymphoid_neoplasm-diffuse_large_B_cell_lymphoma | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-large_intestine-lymphoid_neoplasm-diffuse_large_B_cell_lymphoma | 9 | 5 | 17385 | 2587 |
RB1,KRAS,NRAS,TNFAIP3,HRAS |
| 5.419e-03 | -5.22 | storiform_pleomorphic | COSMIC cancer mutations | storiform_pleomorphic | 9 | 5 | 17385 | 2587 |
RB1,KRAS,NRAS,HRAS,ETV6 |
| 5.419e-03 | -5.22 | hamartoma | COSMIC cancer mutations | hamartoma | 9 | 5 | 17385 | 2587 |
GNAS,TSC1,KRAS,STK11,TSC2 |
| 5.422e-03 | -5.22 | GO_NEGATIVE_REGULATION_OF_CYTOPLASMIC_TRANSPORT | MSigDB lists | GO_NEGATIVE_REGULATION_OF_CYTOPLASMIC_TRANSPORT | 114 | 28 | 17377 | 2626 |
TGFB1,CYLD,TXN,NF1,GOPC,RAB23,RANGAP1,SOX4,PARK7,AKAP1,CDK5,CALM2,FKBP1A,RAP1A,KEAP1,SP100,CSK,TONSL,AXIN2,FAM89B,SRI,PKD2,NUP153,MDFIC,BCL2,PARP10,FAF1,SVIP |
| 5.422e-03 | -5.22 | RICKMAN_TUMOR_DIFFERENTIATED_MODERATELY_VS_POORLY_UP | MSigDB lists | RICKMAN_TUMOR_DIFFERENTIATED_MODERATELY_VS_POORLY_UP | 114 | 28 | 17377 | 2626 |
GLT8D1,DENND1B,TRAK1,E2F3,ORC1,CCNF,CHMP2B,C19orf48,NCAPG,ABHD14A,SNRPA,SH3GLB1,ARF4,FANCI,ABHD5,EIF2S2,NSF,DUSP3,MAFK,IMPDH1,SRSF3,KNTC1,GALNT10,BEND3,MARCH2,ATP6V0E1,S100A6,ADCY7 |
| 5.426e-03 | -5.22 | CTPS1 (CTP synthase 1) | protein interactions | 1503 | 69 | 20 | 17029 | 2761 |
CYLD,SNX2,UBXN1,CUL3,CUL1,BRCA1,PKM,MCM2,CLNS1A,CAND1,PDCD10,CS,CTPS1,IMPDH1,TTC4,PPP5C,CDK2,ARRB2,STRAP,NMD3 |
| 5.426e-03 | -5.22 | SAMHD1 (SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1) | protein interactions | 25939 | 69 | 20 | 17029 | 2761 |
HSPH1,RBX1,CUL3,RACGAP1,CCNL2,XPO7,APP,XRCC5,CCNA2,GART,ACTB,KPNA2,COPS6,CDK2,CD81,ZMAT3,FAF1,DDB1,GPATCH4,MSH6 |
| 5.426e-03 | -5.22 | FLII (FLII, actin remodeling protein) | protein interactions | 2314 | 69 | 20 | 17029 | 2761 |
NAT9,PRKDC,DHX9,MYH9,BRCA1,CAPZA2,SRSF5,ANLN,RFC2,OPTN,PDCD6,DGCR8,MYO18A,RTCB,ACTB,CDK2,HNRNPM,CARM1,IFI16,SSSCA1 |
| 5.426e-03 | -5.22 | GPR156 (G protein-coupled receptor 156) | protein interactions | 165829 | 69 | 20 | 17029 | 2761 |
AMPD2,SNX27,SNRNP200,TRAF7,TYW1,ZNF574,CDC23,AP1B1,MAPK14,ZNF696,POLR2A,CDC16,PHTF1,KANSL2,ECD,ARRB2,PDCD2L,CSNK1G3,ANAPC4,ZNF564 |
| 5.433e-03 | -5.22 | GSE17186_CD21LOW_VS_CD21HIGH_TRANSITIONAL_BCELL_UP | MSigDB lists | GSE17186_CD21LOW_VS_CD21HIGH_TRANSITIONAL_BCELL_UP | 183 | 41 | 17377 | 2626 |
ANKH,CENPF,TPX2,SLC29A1,OAT,SLC12A9,RUFY1,COPG2,APP,SPAG5,MAN1A1,CHKA,STARD9,RRBP1,ARHGEF2,MAP3K14,SLC35C2,CNPY3,HTRA2,PSRC1,BIRC3,ASPM,RAD51AP1,TSPAN31,CDC6,WBP1,SMC2,BRCA1,AURKB,PRKRA,RFC2,ATAD2,RBM47,CERS6,ELMO1,ZNF367,RBPJ,CD81,GEN1,LRP8,RAD51D |
| 5.433e-03 | -5.22 | GSE22601_IMMATURE_CD4_SINGLE_POSITIVE_VS_DOUBLE_POSITIVE_THYMOCYTE_DN | MSigDB lists | GSE22601_IMMATURE_CD4_SINGLE_POSITIVE_VS_DOUBLE_POSITIVE_THYMOCYTE_DN | 183 | 41 | 17377 | 2626 |
RMND5A,HIVEP3,HECA,ZNF496,GOLIM4,ST13,SESTD1,SLC41A1,DAP,FAM129A,TOR3A,CDT1,TAP1,MXD4,PPP1R16B,KTN1,PIP4K2A,MXD1,KIAA1147,PRNP,TNFAIP8,RCSD1,TTC3,MGAT5,ARL5A,TGFB1,PBK,PSPC1,ATXN1,GALNT7,PDE3B,ARHGAP15,MTMR3,VEZF1,ZNF367,MAPK6,NFIL3,USP32,CNOT6,NGLY1,TIGD2 |
| 5.433e-03 | -5.22 | GSE42021_TCONV_PLN_VS_TREG_PRECURSORS_THYMUS_UP | MSigDB lists | GSE42021_TCONV_PLN_VS_TREG_PRECURSORS_THYMUS_UP | 183 | 41 | 17377 | 2626 |
UBL3,UBN1,IVNS1ABP,KIAA0232,CERK,NKRF,SEC16A,SLC20A1,PARN,KCMF1,WRB,SLC25A37,ANKRD28,DTL,FLAD1,EXOSC7,MEX3C,PPME1,TTC3,CNN2,MYBL1,RBM15,FAM171A1,CAMSAP1,ZBED5,RRM2,PFKFB3,DCTD,ZFAND5,ODC1,TOLLIP,DERL1,SERTAD2,OSBPL11,APPL2,MEGF9,GALNT10,RRS1,ZMIZ1,ARRB2,RNF139 |
| 5.433e-03 | -5.22 | GSE34515_CD16_NEG_MONOCYTE_VS_DC_DN | MSigDB lists | GSE34515_CD16_NEG_MONOCYTE_VS_DC_DN | 183 | 41 | 17377 | 2626 |
MRPL9,MAX,TSC2,RRP15,CHERP,PHB2,BABAM1,SLC29A1,ELMOD2,RPAIN,FAM192A,CLIC4,BUD31,H2AFY,YIF1B,ABCD1,RPL19,IFT46,PREB,ENPP4,CPNE1,NTPCR,TRIM8,LAP3,CREG1,NSUN2,IL12RB1,METTL22,GSTCD,BORA,PRPSAP1,EIF3G,BSDC1,NSA2,PFDN5,BRD2,CERS6,CORO1C,NDUFS5,PPP5C,TMEM131 |
| 5.433e-03 | -5.22 | GSE3982_MAST_CELL_VS_MAC_UP | MSigDB lists | GSE3982_MAST_CELL_VS_MAC_UP | 183 | 41 | 17377 | 2626 |
CASP6,TMX4,CUTA,FLOT1,CTCF,DCUN1D4,PRKACA,HMG20A,MIS12,RPL11,EXOSC1,CTR9,CNN2,MINPP1,ALDH18A1,LUC7L2,SP3,IFRD1,HMGN1,RHOBTB3,TSPYL4,PRKDC,TEX10,RNPS1,WDR82,EIF2AK1,SRSF5,ESYT1,CDC23,CYFIP2,GAR1,RPL36,UTP20,JAK1,PPP3R1,MRFAP1L1,ACTB,TFDP2,TMEM14A,RTN3,PURA |
| 5.433e-03 | -5.22 | GSE7831_1H_VS_4H_CPG_STIM_PDC_UP | MSigDB lists | GSE7831_1H_VS_4H_CPG_STIM_PDC_UP | 183 | 41 | 17377 | 2626 |
TMUB1,SESTD1,HMGXB3,MAGED1,GSPT2,PTTG1,VPS45,LANCL1,CDIPT,MAPK14,ANKIB1,BIRC2,RNF103,EDC3,GTF2F1,SAR1A,RBM34,SSBP3,CNPY4,ARHGEF2,PIK3IP1,MED22,TXNL1,SGCE,TRAFD1,ETV3,LDB1,SEPT8,EDEM2,CBFA2T2,TXNL4A,NDRG3,DDX17,AMZ2,TBC1D17,GRIPAP1,PML,PKD2,DUSP11,ATP6V0C,CHPF2 |
| 5.433e-03 | -5.22 | GSE17721_POLYIC_VS_PAM3CSK4_24H_BMDC_DN | MSigDB lists | GSE17721_POLYIC_VS_PAM3CSK4_24H_BMDC_DN | 183 | 41 | 17377 | 2626 |
NDUFV2,GMFG,ANXA6,DHPS,ANKH,LAGE3,TMEM97,CHAC2,STMN1,MYEF2,MAD2L2,SNRNP25,SMC3,SNX18,BTF3L4,CAPZA1,MRPL48,RNF19A,MRPL11,NDUFA3,LRRC59,LPCAT1,FTSJ3,PREB,EIF5A,MOB4,ADAM17,SEC61B,PRIM2,PBXIP1,E2F3,WBP2,RPL27A,ADSS,KIF2A,SLC19A1,CEP55,ADAM9,COPS6,UBE2C,DDB1 |
| 5.433e-03 | -5.22 | GSE5589_WT_VS_IL6_KO_LPS_AND_IL10_STIM_MACROPHAGE_45MIN_DN | MSigDB lists | GSE5589_WT_VS_IL6_KO_LPS_AND_IL10_STIM_MACROPHAGE_45MIN_DN | 183 | 41 | 17377 | 2626 |
TRIP12,MRI1,ARGLU1,CSNK1A1,ZADH2,KTN1,TFRC,PIP5K1C,RTKN,KIF5B,NUDT19,ASAP2,CLIC4,ITGB8,UTP18,HDAC7,ZCCHC2,FEM1B,SLC35A1,FTSJ3,ABCC5,SOCS5,SEPT9,NCK1,ABCF2,MRPL43,SLC26A6,ARHGEF12,SMAD2,SPATA2,PITX1,PPA2,PGRMC1,CEBPG,RBMS1,DUSP11,RGL1,MAPK1,LTA4H,C7orf26,TMEM33 |
| 5.433e-03 | -5.22 | GSE36476_CTRL_VS_TSST_ACT_16H_MEMORY_CD4_TCELL_YOUNG_UP | MSigDB lists | GSE36476_CTRL_VS_TSST_ACT_16H_MEMORY_CD4_TCELL_YOUNG_UP | 183 | 41 | 17377 | 2626 |
FGFR1OP,HECA,TSC22D3,TMX4,YTHDF3,DNAJB1,RLF,CHD1,FAM8A1,MOAP1,ADD3,ZNF639,ZNF226,CRY2,PIK3IP1,CNN2,TTC17,PIKFYVE,PLCL2,CITED2,MYBL1,USP34,PPP3CA,MAPRE2,TNFAIP3,RB1CC1,TSPYL4,PBXIP1,CIRBP,ARHGDIB,NDRG3,ARHGAP15,MYO1F,FBXO21,SGSH,OSBPL8,PIAS2,HMGB2,MAP3K5,CCDC59,TOB1 |
| 5.433e-03 | -5.22 | GSE12198_NK_VS_NK_ACT_EXPANSION_SYSTEM_DERIVED_NK_CELL_UP | MSigDB lists | GSE12198_NK_VS_NK_ACT_EXPANSION_SYSTEM_DERIVED_NK_CELL_UP | 183 | 41 | 17377 | 2626 |
SLC41A1,MRI1,GADD45G,HAUS4,PAPOLA,SLC25A36,PRNP,DLG5,PDCD10,NUS1,INPP5A,SNX18,MBD2,PIK3R2,ZNF260,SLC35B4,RPN2,YTHDC1,RFC3,FAM118B,PGS1,CCDC34,TTC33,ERC1,KIF2A,GOLGA7,MAFK,WNT5B,NFIL3,CTBS,DUSP11,ATF6,DTD1,SPCS3,MAP3K5,RUFY3,NGLY1,CPEB2,RAD51D,RHEBL1,PRPF4B |
| 5.433e-03 | -5.22 | GSE27786_LSK_VS_CD4_TCELL_UP | MSigDB lists | GSE27786_LSK_VS_CD4_TCELL_UP | 183 | 41 | 17377 | 2626 |
TMEM106C,GALK1,PIGN,SRSF6,TMEM97,RUFY1,STAM,CPNE3,MOAP1,SUV39H2,LRRC8D,ZDHHC13,HTRA2,MED22,MLST8,GINS1,PLK1,NTPCR,PSPC1,ACSL3,PPIE,RHOT1,VDAC1,CCNF,CLNS1A,AKAP1,PWWP2B,ZNF777,HSPBP1,PEX5,MAGT1,PKD2,SMPD4,RUVBL2,NR2F2,SMAD1,SASS6,ARHGAP23,C11orf1,PDSS2,SNAPIN |
| 5.433e-03 | -5.22 | GSE10240_CTRL_VS_IL17_AND_IL22_STIM_PRIMARY_BRONCHIAL_EPITHELIAL_CELLS_UP | MSigDB lists | GSE10240_CTRL_VS_IL17_AND_IL22_STIM_PRIMARY_BRONCHIAL_EPITHELIAL_CELLS_UP | 183 | 41 | 17377 | 2626 |
WSB2,NAT9,MAX,C19orf53,DEPDC1,CDCA8,SMARCA4,KIF2C,LACTB2,SPAG5,ZNF428,MED8,PPME1,ARF5,TTC4,GLE1,CENPM,SEH1L,TACC3,TDP1,KIAA0040,OAF,ABCF2,TUFM,HTATIP2,CKAP2L,MASTL,KIF18A,MTHFD2,TWSG1,NEIL3,ARNTL,WDR4,MEGF9,NCLN,STK11,GEN1,UBE2C,PDSS2,ESPL1,PPP2R2D |
| 5.433e-03 | -5.22 | GSE21546_ELK1_KO_VS_SAP1A_KO_AND_ELK1_KO_ANTI_CD3_STIM_DP_THYMOCYTES_DN | MSigDB lists | GSE21546_ELK1_KO_VS_SAP1A_KO_AND_ELK1_KO_ANTI_CD3_STIM_DP_THYMOCYTES_DN | 183 | 41 | 17377 | 2626 |
HSPH1,PHRF1,B4GALT5,KIAA0232,ETS1,PITHD1,KCMF1,CHKA,ABL2,PDXP,MDM2,MTA1,AHSA1,GRSF1,LPIN2,TAGLN2,CABLES2,POLR1B,GLE1,CNPY3,YTHDC1,SRP72,TRAPPC9,TNFAIP3,C16orf72,DENND1B,DHX29,AZI2,ARL5B,SERP1,NMT2,SEPT1,ZNF777,CLK3,DHX16,CSNK1G1,CORO1C,ZNF367,GADD45B,BEND3,RUFY3 |
| 5.433e-03 | -5.22 | GSE41176_UNSTIM_VS_ANTI_IGM_STIM_BCELL_3H_DN | MSigDB lists | GSE41176_UNSTIM_VS_ANTI_IGM_STIM_BCELL_3H_DN | 183 | 41 | 17377 | 2626 |
UFC1,COX4I1,USP48,RGS2,STMN1,CPNE3,NFATC3,ZNF75D,CTSS,SNUPN,MSH2,GPATCH1,KIF22,AFF1,CEP63,CNPY3,SLC35A1,TPCN1,CAMK2G,PRPF19,ADCY7,EIF3L,DCAF8,OXR1,NOL8,ZNF574,SMC2,RHOT1,MACF1,SLC50A1,MAN2A2,SCARB2,HHEX,FBXO41,TTC13,QARS,ZDHHC7,USP20,MLYCD,IFI16,AAAS |
| 5.435e-03 | -5.21 | YEATS4 (YEATS domain containing 4) | protein interactions | 8089 | 136 | 34 | 17029 | 2761 |
CCDC93,MAX,H2AFZ,PTTG1,NSD3,NUF2,HDGFL2,PSMD9,LYN,GIT2,HMG20A,MEAF6,OIP5,SNUPN,KLF16,RABGAP1L,JAZF1,ANP32A,S100A6,AGGF1,RPRD1A,TACC1,GABPA,RCOR1,DOT1L,UBTF,SUGP1,GRIPAP1,ARNTL,MYO18A,PPM1G,RUVBL2,FUS,PPP2R2D |
| 5.436e-03 | -5.21 | HUANG_DASATINIB_RESISTANCE_DN | MSigDB lists | HUANG_DASATINIB_RESISTANCE_DN | 64 | 18 | 17377 | 2626 |
UBL3,ABCA3,ACSL3,CRNKL1,ABHD11,MYEF2,RHOB,CERS6,LUC7L3,MEGF9,SCARB1,CLN3,METTL9,GPD1L,CHPT1,TOB1,SLC35A1,PDCD4 |
| 5.436e-03 | -5.21 | GO_HISTONE_METHYLTRANSFERASE_COMPLEX | MSigDB lists | GO_HISTONE_METHYLTRANSFERASE_COMPLEX | 64 | 18 | 17377 | 2626 |
MAX,CXXC1,SUZ12,TEX10,WDR82,EZH1,WDR5,MEN1,STK38,PRDM4,ZNF335,OGT,H2AFY,ACTB,RUVBL2,RBBP4,TAF6,HDAC2 |
| 5.462e-03 | -5.21 | Regulation of mRNA stability by proteins that bind AU-rich elements | REACTOME pathways | R-HSA-450531 | 91 | 25 | 10287 | 1696 |
EXOSC6,PSMA8,PSMB7,PSMA1,EXOSC9,PSMD9,MAPK14,PSMB9,PARN,PSMB3,PSMC4,PSMD2,PSMD1,PSMA6,EXOSC7,RPS27A,PSMD8,PSMD3,EXOSC1,DCP1A,ANP32A,KHSRP,YWHAZ,PSMC1,PABPC1 |
| 5.472e-03 | -5.21 | V$STAT1_02 | MSigDB lists | V$STAT1_02 | 238 | 51 | 17377 | 2626 |
HIVEP3,UBL3,CHMP2A,PRPF38B,DDX47,POC1A,UFC1,SIKE1,CSNK1A1,PRKACA,FBRS,HNRNPA2B1,MRPL50,USF1,ZNF420,SHC1,DDA1,SRSF4,NOC2L,CS,MRPL34,MRPL54,PCYT2,POLR1B,ZNF189,PRPF19,NRAS,NASP,TSTA3,ERF,E2F3,SREK1,LRP5,BCLAF1,SOX4,STX16,SYMPK,RDH11,CBX3,VEZF1,NUCB1,HHEX,DDOST,TIMM17A,CAMKMT,COX8A,FTSJ1,CAB39,UQCRH,ZRANB2,PREPL |
| 5.473e-03 | -5.21 | CHD3 (chromodomain helicase DNA binding protein 3) | protein interactions | 1107 | 156 | 38 | 17029 | 2761 |
HSPH1,IMMT,CASP6,IVNS1ABP,SUMO2,UROD,HABP4,CSNK2A1,RGS2,UBE2I,SRRT,MTA1,MBD2,CREB1,LUC7L2,ATP5IF1,PHF20L1,RPL29,MTA2,KIF15,MCM2,MBD3,TRIM28,PHF6,MAN2A2,SERF2,GPS2,CHD3,ZHX1,SAFB,UHRF2,DDX5,KPNA2,RBBP4,TAF6,XRCC4,HDAC2,FUBP1 |
| 5.477e-03 | -5.21 | MLH1 (mutL homolog 1) | protein interactions | 4292 | 146 | 36 | 17029 | 2761 |
EXOC3,DDX47,TXN,PARP12,ANXA6,PMS2,PPP3CB,BLM,USP5,ABHD16A,MBD4,ZER1,PCNA,RAD23B,MSH2,AP2B1,ATF2,MSH6,SLC25A1,SPTAN1,PRKDC,PSMA1,CAPZA2,EIF2A,BRCA1,API5,SEC61A1,NT5C3B,E2F4,CDCA7L,E2F1,KPNA2,ATP5F1A,RUVBL2,NANP,PPP2R2D |
| 5.477e-03 | -5.21 | CDC16 (cell division cycle 16) | protein interactions | 8881 | 146 | 36 | 17029 | 2761 |
KRBA1,C16orf87,CCNB1,ATP5PF,YY1AP1,FBXO5,RB1,CCP110,SNX18,ZNHIT6,GTSE1,ANAPC7,NAP1L4,CDC5L,JMJD4,ERF,ASPM,ANAPC2,KRAS,DNAJA1,BRCA1,CDC23,HAUS8,XRCC5,EIF4ENIF1,SMAD2,CDC27,DUS3L,HINT1,UHRF2,PPP5C,MYO9A,FAM208A,LONP2,ESPL1,ANAPC4 |
| 5.479e-03 | -5.21 | REACTOME_GLOBAL_GENOMIC_NER_GG_NER | MSigDB lists | REACTOME_GLOBAL_GENOMIC_NER_GG_NER | 32 | 11 | 17377 | 2626 |
RPA2,ERCC1,PCNA,RFC3,POLE,XPA,RAD23B,GTF2H2,RFC2,DDB1,RPA1 |
| 5.479e-03 | -5.21 | PID_WNT_NONCANONICAL_PATHWAY | MSigDB lists | PID_WNT_NONCANONICAL_PATHWAY | 32 | 11 | 17377 | 2626 |
RHOA,CDC42,TAB2,RAC1,NFATC2,DVL1,ROCK1,ARRB2,CSNK1A1,DVL2,FZD6 |
| 5.479e-03 | -5.21 | MODULE_28 | MSigDB lists | MODULE_28 | 32 | 11 | 17377 | 2626 |
PSMD2,PSMD1,PSMA6,PSMD8,PSMD3,PSMB7,PSMA1,PSMD9,PSMC1,PSMB3,PSMC4 |
| 5.479e-03 | -5.21 | DORSAM_HOXA9_TARGETS_DN | MSigDB lists | DORSAM_HOXA9_TARGETS_DN | 32 | 11 | 17377 | 2626 |
SRP72,SRSF11,MAN2A2,OSBPL8,VHL,TSC22D3,ARNTL,FXR1,LYN,DYNC1LI2,CDC37 |
| 5.479e-03 | -5.21 | PID_NETRIN_PATHWAY | MSigDB lists | PID_NETRIN_PATHWAY | 32 | 11 | 17377 | 2626 |
RHOA,CDC42,NCK1,ELMO1,RAC1,TRIO,DAPK1,PITPNA,MAPK1,MAP2K2,MAPK3 |
| 5.497e-03 | -5.20 | GO_NEGATIVE_REGULATION_OF_CATABOLIC_PROCESS | MSigDB lists | GO_NEGATIVE_REGULATION_OF_CATABOLIC_PROCESS | 194 | 43 | 17377 | 2626 |
ZNF207,FEZ2,PHF23,KDM4A,DAP,UBXN1,PRKAA1,CENPF,CSNK2A1,SECISBP2,SIRT2,BCL2L1,PSEN1,PARK7,MAD2L2,TBC1D14,PIN1,BCL2,STAT3,SENP1,PABPC1,PDCL3,RNF5,PLK1,UBQLN4,TIMP2,PBK,PDE3B,TSC1,CHMP4A,GOLGA2,TAB2,LRPPRC,PML,CHMP4B,CLN3,SNRNP70,SMAD4,TOB1,TERF1,CDKN2A,SVIP,EGLN1 |
| 5.499e-03 | -5.20 | MIF4-like_sf | interpro domains | IPR016021 | 16 | 7 | 18492 | 2768 |
UPF2,MIF4GD,EIF5,EIF4G2,BZW2,PAIP1,PDCD4 |
| 5.513e-03 | -5.20 | GO_MICROTUBULE_ORGANIZING_CENTER_PART | MSigDB lists | GO_MICROTUBULE_ORGANIZING_CENTER_PART | 135 | 32 | 17377 | 2626 |
MZT1,FOPNL,POC1A,TUBGCP5,FLOT1,TOPORS,SIRT2,BRCA1,CNTROB,CCNF,TUBGCP2,SPAG5,HSPA1B,STARD9,RAB8A,CEP104,MZT2A,PCM1,NEK1,CCP110,BIRC5,CCDC14,CENPJ,ODF2,CEP55,RP2,CEP63,ROCK1,WDR62,SASS6,MZT2B,POC5 |
| 5.529e-03 | -5.20 | TEAD2 (TEA domain transcription factor 2) | protein interactions | 8463 | 83 | 23 | 17029 | 2761 |
RECQL,TRIP12,MECP2,BTAF1,CHD1L,MYBL2,KRAS,DCUN1D5,DDX39A,CHAF1A,SUPT16H,LIN9,SMC3,CDC27,HUWE1,H2AFY,KIF22,NCOA1,SMPD4,NR2F2,USP11,ORC3,USF2 |
| 5.532e-03 | -5.20 | pleomorphic | COSMIC cancer mutations | pleomorphic | 24 | 9 | 17385 | 2587 |
RB1,EWSR1,NRAS,NF1,PTEN,KRAS,FUS,HRAS,CDKN2A |
| 5.532e-03 | -5.20 | basal_cell_carcinoma | COSMIC cancer mutations | basal_cell_carcinoma | 24 | 9 | 17385 | 2587 |
FGFR3,CYLD,NRAS,KRAS,NOTCH2,H3F3A,STAT3,HRAS,CDKN2A |
| 5.546e-03 | -5.19 | endometrium-carcinoma | COSMIC cancer mutations | endometrium-carcinoma | 46 | 14 | 17385 | 2587 |
FGFR3,RB1,NRAS,NF1,PTEN,VHL,SF3B1,AXIN1,MSH2,STK11,KRAS,BRCA1,HRAS,MSH6 |
| 5.547e-03 | -5.19 | GSE7509_UNSTIM_VS_FCGRIIB_STIM_DC_UP | MSigDB lists | GSE7509_UNSTIM_VS_FCGRIIB_STIM_DC_UP | 167 | 38 | 17377 | 2626 |
NCOR2,MCM10,PHB2,MRPL39,NACA,CDCA3,CERK,CDCA8,RACGAP1,KIF2C,PMF1,PMVK,PIK3R2,PRC1,SLC27A4,KIF22,FBXL7,PCYT2,CDC25B,FBXL19,TACC3,RNF169,TMED2,TIMM50,SOCS5,TACC1,ZMYND11,MYBL2,CKAP2L,LRP5,CCNF,TMEM201,NEU1,EVC2,FAM83D,ACBD4,BEND6,CCNB2 |
| 5.564e-03 | -5.19 | STI1_HS-bd | interpro domains | IPR006636 | 9 | 5 | 18492 | 2768 |
UBQLN4,UBQLN2,ST13,RAD23B,RAD23A |
| 5.564e-03 | -5.19 | Lactate_DH/Glyco_Ohase_4_C | interpro domains | IPR015955 | 9 | 5 | 18492 | 2768 |
MDH1,UEVLD,MDH2,LDHA,LDHB |
| 5.579e-03 | -5.19 | GTGCCAA,MIR-96 | MSigDB lists | GTGCCAA,MIR-96 | 283 | 59 | 17377 | 2626 |
ANKRD27,LUZP1,TM9SF4,TSC22D3,MECP2,XIAP,UCK2,SDC2,STARD7,RAB23,GGA2,RGS2,AP3S1,RUFY1,CRKL,TNS3,SHC1,BRPF3,INPP5A,RAB35,JAZF1,PPP1R12C,SEPT11,ABCD1,EIF5,CNNM3,SLC35A1,SCYL3,TMX1,SLC25A1,PPP1R9B,PHF20L1,FAM49B,CELSR2,TACC1,ATG9A,ERLIN1,LDB1,SLC16A7,POLR2D,EZR,ATXN1,KRAS,ARHGEF12,MTMR12,ZFAND5,BSDC1,AKAP1,MTMR3,SH3BP5,CACNB1,GALNT2,BRWD1,ZHX1,OGT,PPP3R1,WIPI2,RNF139,ABCA1 |
| 5.589e-03 | -5.19 | human chr1p35.3 | chromosome location | human chr1p35.3 | 38 | 10 | 26185 | 2809 |
RPA2,ATP5IF1,DNAJC8,PPP1R8,GMEB1,SRSF4,FAM76A,MECR,TAF12,EPB41 |
| 5.599e-03 | -5.19 | paraganglioma | COSMIC cancer mutations | paraganglioma | 70 | 19 | 17385 | 2587 |
MAX,NRAS,GUK1,GALC,NF1,VHL,KRAS,NOTCH2,KMT2C,MEN1,PRPSAP1,STYXL1,SDHA,CHD1,GNAS,RAB35,WIPI2,HRAS,CDKN2A |
| 5.601e-03 | -5.18 | PID_HDAC_CLASSI_PATHWAY | MSigDB lists | PID_HDAC_CLASSI_PATHWAY | 69 | 19 | 17377 | 2626 |
NCOR2,MAX,MTA2,RANGAP1,SIRT2,UBE2I,PRKACA,MBD3,FKBP3,MXD1,CHD3,MBD2,HDAC7,YY1,RBBP4,SMURF1,STAT3,HDAC2,SAP30 |
| 5.601e-03 | -5.18 | AGTCTTA,MIR-499 | MSigDB lists | AGTCTTA,MIR-499 | 69 | 19 | 17377 | 2626 |
PPP3CA,ZBTB10,H2AFZ,ADAM10,UBN1,ARID2,MECP2,SDC2,ARGLU1,UBE2V1,EML4,MYEF2,SEC11A,DGCR8,MAPK6,VCPIP1,FOXN2,PDCD4,RYBP |
| 5.601e-03 | -5.18 | PID_VEGFR1_2_PATHWAY | MSigDB lists | PID_VEGFR1_2_PATHWAY | 69 | 19 | 17377 | 2626 |
PDPK1,PRKAB1,RHOA,NCK1,RAF1,PRKAA1,ARF1,PRKACA,MAPK14,MAP2K2,MAPK3,AKAP1,PTPN2,HGS,CDC42,DNM2,PTPN11,ROCK1,MAPK1 |
| 5.604e-03 | -5.18 | GO_AEROBIC_RESPIRATION | MSigDB lists | GO_AEROBIC_RESPIRATION | 50 | 15 | 17377 | 2626 |
CAT,SDHB,NDUFV1,SUCLG1,UQCR10,MDH2,IDH3A,CS,SUCLG2,DHTKD1,UQCRH,MDH1,OGDH,IDH3B,SDHA |
| 5.604e-03 | -5.18 | GO_ER_TO_GOLGI_TRANSPORT_VESICLE_MEMBRANE | MSigDB lists | GO_ER_TO_GOLGI_TRANSPORT_VESICLE_MEMBRANE | 50 | 15 | 17377 | 2626 |
SEC31A,CD59,HLA-B,TMED7,USO1,SEC23IP,TMED10,SCAP,HLA-E,SEC24C,VTI1A,MCFD2,LMAN1,HLA-A,TMED2 |
| 5.604e-03 | -5.18 | GO_CELLULAR_RESPONSE_TO_IONIZING_RADIATION | MSigDB lists | GO_CELLULAR_RESPONSE_TO_IONIZING_RADIATION | 50 | 15 | 17377 | 2626 |
INTS7,NET1,RAD51AP1,ITGB1,TMEM109,H2AFX,DNM2,BCL2L1,ELK1,BLM,MAPK14,RHOB,IFI16,EEF1D,XRCC5 |
| 5.604e-03 | -5.18 | SIG_INSULIN_RECEPTOR_PATHWAY_IN_CARDIAC_MYOCYTES | MSigDB lists | SIG_INSULIN_RECEPTOR_PATHWAY_IN_CARDIAC_MYOCYTES | 50 | 15 | 17377 | 2626 |
PDPK1,BRD4,SHC1,CDC42,PTEN,AKT2,RPS6KA1,RAF1,FLOT1,YWHAZ,MAPK1,YWHAH,PARD3,CDKN2A,MAPK3 |
| 5.606e-03 | -5.18 | dermatofibrosarcoma_protuberans | COSMIC cancer mutations | dermatofibrosarcoma_protuberans | 20 | 8 | 17385 | 2587 |
KRAS,FUS,NRAS,SAFB2,PTEN,HRAS,ETV6,MSH2 |
| 5.606e-03 | -5.18 | soft_tissue-fibrous_tissue_and_uncertain_origin-dermatofibrosarcoma_protuberans | COSMIC cancer mutations | soft_tissue-fibrous_tissue_and_uncertain_origin-dermatofibrosarcoma_protuberans | 20 | 8 | 17385 | 2587 |
KRAS,FUS,NRAS,SAFB2,PTEN,HRAS,ETV6,MSH2 |
| 5.620e-03 | -5.18 | CD95 death-inducing signaling complex | cellular component | GO:0031265 | 6 | 4 | 18223 | 2701 |
FAF1,FADD,CFLAR,FAS |
| 5.620e-03 | -5.18 | histone pre-mRNA 3'end processing complex | cellular component | GO:0071204 | 6 | 4 | 18223 | 2701 |
SLBP,YBX1,SYNCRIP,SNRPB |
| 5.620e-03 | -5.18 | CRD-mediated mRNA stability complex | cellular component | GO:0070937 | 6 | 4 | 18223 | 2701 |
CSDE1,YBX1,SYNCRIP,DHX9 |
| 5.620e-03 | -5.18 | alpha DNA polymerase:primase complex | cellular component | GO:0005658 | 6 | 4 | 18223 | 2701 |
POLA2,PRIM2,HELB,PRIM1 |
| 5.620e-03 | -5.18 | gamma-secretase complex | cellular component | GO:0070765 | 6 | 4 | 18223 | 2701 |
TMED10,PSEN1,APH1A,APH1B |
| 5.620e-03 | -5.18 | vacuolar proton-transporting V-type ATPase, V0 domain | cellular component | GO:0000220 | 6 | 4 | 18223 | 2701 |
ATP6V0A1,ATP6V0A2,ATP6V0C,ATP6V0B |
| 5.624e-03 | -5.18 | KLF11 (Kruppel like factor 11) | protein interactions | 8462 | 15 | 7 | 17029 | 2761 |
ATXN1,YWHAZ,CLU,TIMM13,MAPK1,APH1A,CBX3 |
| 5.624e-03 | -5.18 | Rab5b (RAB5B, member RAS oncogene family) | protein interactions | 19344 | 15 | 7 | 17029 | 2761 |
LETMD1,EIF3L,CLSPN,CDC27,ASXL2,KCNAB2,TMEM201 |
| 5.624e-03 | -5.18 | GABRD (gamma-aminobutyric acid type A receptor delta subunit) | protein interactions | 2563 | 15 | 7 | 17029 | 2761 |
UBQLN4,ATF6,TTC17,ATG9A,FUT8,DNAJB9,TMEM131 |
| 5.624e-03 | -5.18 | DIXDC1 (DIX domain containing 1) | protein interactions | 85458 | 15 | 7 | 17029 | 2761 |
MYH9,MAP3K4,ATXN1,CAPZA2,APP,AXIN1,CDC5L |
| 5.624e-03 | -5.18 | GTPBP3 (GTP binding protein 3, mitochondrial) | protein interactions | 84705 | 15 | 7 | 17029 | 2761 |
GTPBP3,PRPF3,SINHCAF,LYN,CIC,DCAF8,GNE |
| 5.626e-03 | -5.18 | HALLMARK_PI3K_AKT_MTOR_SIGNALING | MSigDB lists | HALLMARK_PI3K_AKT_MTOR_SIGNALING | 104 | 26 | 17377 | 2626 |
UBE2D3,TSC2,NCK1,RPS6KA1,RAF1,ACTR3,RAC1,SLC2A1,AKT1S1,ARF1,RIT1,MKNK1,SMAD2,PTEN,DUSP3,RALB,PIN1,E2F1,PTPN11,CAB39,CDKN1B,PIKFYVE,CDK2,MAPK1,HRAS,CFL1 |
| 5.644e-03 | -5.18 | Cyclin A/B1 associated events during G2/M transition | REACTOME pathways | R-HSA-69273 | 22 | 9 | 10287 | 1696 |
PLK1,PPP2CA,CCNA2,FOXM1,PKMYT1,CDC25B,CCNB1,CDK2,CCNB2 |
| 5.664e-03 | -5.17 | GSE22611_UNSTIM_VS_6H_MDP_STIM_MUTANT_NOD2_TRANSDUCED_HEK293T_CELL_UP | MSigDB lists | GSE22611_UNSTIM_VS_6H_MDP_STIM_MUTANT_NOD2_TRANSDUCED_HEK293T_CELL_UP | 178 | 40 | 17377 | 2626 |
NADSYN1,HECA,TMEM184B,GNPDA1,SRSF6,TOR3A,UFC1,ANKH,SLC25A12,PRNP,SEC11A,PIGG,DDX31,RP2,MARCH2,CTDSP2,ARL5A,CARM1,CSTF1,UBQLN4,CDKN2AIP,JTB,RPS24,MRPS10,CDC23,MBD3,SH3BP5,AGPAT2,CSK,CCDC6,STAT6,STX18,PTPN7,DMWD,IDH3B,TOB1,LRP8,HIGD2A,PDCD4,ANXA11 |
| 5.664e-03 | -5.17 | GSE25087_TREG_VS_TCONV_ADULT_UP | MSigDB lists | GSE25087_TREG_VS_TCONV_ADULT_UP | 178 | 40 | 17377 | 2626 |
DYNLL1,FAM129A,SRGN,UCK2,CBLL1,USP48,S1PR2,PPP1R16B,FBXO3,IRF4,RAP1A,CCDC50,RALB,CAPZA1,ANXA5,BCL2,CLDND1,RNF19A,MYBL1,TIPARP,ABCC1,ELOVL5,ELL2,CPOX,IL12RB1,EIF3A,OPTN,SGSH,ATAD2,SURF4,TXNDC16,TAB2,RBL1,CEP55,PTPN7,VCPIP1,SLC16A1,SAMD8,TRAF5,GLCCI1 |
| 5.664e-03 | -5.17 | GSE2405_0H_VS_6H_A_PHAGOCYTOPHILUM_STIM_NEUTROPHIL_UP | MSigDB lists | GSE2405_0H_VS_6H_A_PHAGOCYTOPHILUM_STIM_NEUTROPHIL_UP | 178 | 40 | 17377 | 2626 |
PWWP2A,TBC1D12,TOMM20,TXN,URB2,SESTD1,TKT,SMARCA4,UBE2I,RPA2,TMEM69,ZNF473,ZNHIT6,ZNF746,XPA,SRI,ZBTB22,ZRANB1,SLC35A1,TMEM14C,SYTL3,SMC4,TXNL1,PPP1R9B,ZNF672,TSPYL4,USP42,SMU1,PSMB7,PSMA1,RTF1,PRMT2,TAZ,STYXL1,XRCC5,PRDX3,USP20,TMEM14A,SMURF1,TSPAN5 |
| 5.692e-03 | -5.17 | STAT5A (signal transducer and activator of transcription 5A) | protein interactions | 6776 | 107 | 28 | 17029 | 2761 |
TCF12,PPIB,NCOR2,ERMP1,NARF,SMARCA4,GLUD1,BRCA1,GNB2,PDHX,MAPK3,SOCS7,CRKL,PTPN2,PPP2CA,PDK2,ADD3,SHC1,JAK1,CENPJ,RBMX,STAT1,PTPN11,NCOA1,MAPK1,STAT3,ILKAP,CARM1 |
| 5.693e-03 | -5.17 | microtubule-based movement | biological process | GO:0007018 | 293 | 61 | 17256 | 2622 |
KIF3B,DYNLL1,ACTR3,TRAK1,DNAAF5,AP3M2,MYH9,KIF23,KLC1,RACGAP1,KIF2C,RAB6A,MYO9B,AP3S1,IFT27,APP,KTN1,COPG2,DST,KIF5B,KIFC1,CLUAP1,RAB21,STARD9,CDC42,AP3S2,KIF14,KIF13B,AP2B1,KIFAP3,KIF22,IFT46,DNAL4,MYO5A,TERF2,DCTN1,KIF15,BICD2,RAB1A,FXR1,RHOT1,KIF11,RHOT2,TMEM201,BBS12,MYO1F,KIF2A,KIF18A,HSPB11,PCM1,KIF18B,MAP4,MYO18A,LRPPRC,SSNA1,NDE1,CLN3,MYO9A,AP2S1,DYNC1LI2,SNAPIN |
| 5.703e-03 | -5.17 | urinary_tract-ureter-carcinoma | COSMIC cancer mutations | urinary_tract-ureter-carcinoma | 6 | 4 | 17385 | 2587 |
KRAS,NRAS,HRAS,CDKN2A |
| 5.703e-03 | -5.17 | skin-in_situ_epithelial_neoplasm-Bowen_disease | COSMIC cancer mutations | skin-in_situ_epithelial_neoplasm-Bowen_disease | 6 | 4 | 17385 | 2587 |
FGFR3,KRAS,NRAS,HRAS |
| 5.703e-03 | -5.17 | liver-other-hyperplasia | COSMIC cancer mutations | liver-other-hyperplasia | 6 | 4 | 17385 | 2587 |
GNAS,STAT3,IL6ST,AXIN1 |
| 5.703e-03 | -5.17 | pituitary-adenoma-ACTH_non_functioning | COSMIC cancer mutations | pituitary-adenoma-ACTH_non_functioning | 6 | 4 | 17385 | 2587 |
CDKN2C,RB1,AXIN1,CDKN2A |
| 5.703e-03 | -5.17 | leiomyoblastoma | COSMIC cancer mutations | leiomyoblastoma | 6 | 4 | 17385 | 2587 |
KRAS,NRAS,SF3B1,HRAS |
| 5.703e-03 | -5.17 | skin-head_neck-epidermal_nevus | COSMIC cancer mutations | skin-head_neck-epidermal_nevus | 6 | 4 | 17385 | 2587 |
FGFR3,KRAS,NRAS,HRAS |
| 5.703e-03 | -5.17 | cervix-carcinoma-clear_cell_carcinoma | COSMIC cancer mutations | cervix-carcinoma-clear_cell_carcinoma | 6 | 4 | 17385 | 2587 |
KRAS,STK11,NRAS,HRAS |
| 5.703e-03 | -5.17 | skin-arm-epidermal_nevus | COSMIC cancer mutations | skin-arm-epidermal_nevus | 6 | 4 | 17385 | 2587 |
FGFR3,KRAS,NRAS,HRAS |
| 5.703e-03 | -5.17 | skin-trunk-epidermal_nevus | COSMIC cancer mutations | skin-trunk-epidermal_nevus | 6 | 4 | 17385 | 2587 |
FGFR3,KRAS,NRAS,HRAS |
| 5.703e-03 | -5.17 | skin-flank-other-seborrhoeic_keratosis | COSMIC cancer mutations | skin-flank-other-seborrhoeic_keratosis | 6 | 4 | 17385 | 2587 |
FGFR3,PTEN,HRAS,PTPN11 |
| 5.703e-03 | -5.17 | haematopoietic_and_lymphoid_tissue-thyroid-lymphoid_neoplasm | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-thyroid-lymphoid_neoplasm | 6 | 4 | 17385 | 2587 |
KRAS,NRAS,CCDC6,HRAS |
| 5.703e-03 | -5.17 | lentiginous_nevus | COSMIC cancer mutations | lentiginous_nevus | 6 | 4 | 17385 | 2587 |
FGFR3,KRAS,NRAS,HRAS |
| 5.703e-03 | -5.17 | skin-back-other-seborrhoeic_keratosis | COSMIC cancer mutations | skin-back-other-seborrhoeic_keratosis | 6 | 4 | 17385 | 2587 |
FGFR3,PTEN,HRAS,PTPN11 |
| 5.703e-03 | -5.17 | soft_tissue-smooth_muscle-leiomyoblastoma | COSMIC cancer mutations | soft_tissue-smooth_muscle-leiomyoblastoma | 6 | 4 | 17385 | 2587 |
KRAS,NRAS,SF3B1,HRAS |
| 5.703e-03 | -5.17 | skin-epidermal_nevus | COSMIC cancer mutations | skin-epidermal_nevus | 6 | 4 | 17385 | 2587 |
FGFR3,KRAS,NRAS,HRAS |
| 5.703e-03 | -5.17 | upper_aerodigestive_tract-larynx-carcinoma-adenoid_cystic_carcinoma | COSMIC cancer mutations | upper_aerodigestive_tract-larynx-carcinoma-adenoid_cystic_carcinoma | 6 | 4 | 17385 | 2587 |
KRAS,NRAS,HRAS,CDKN2A |
| 5.703e-03 | -5.17 | upper_aerodigestive_tract-mouth-other-epithelial_hyperplasia | COSMIC cancer mutations | upper_aerodigestive_tract-mouth-other-epithelial_hyperplasia | 6 | 4 | 17385 | 2587 |
KRAS,NRAS,HRAS,CDKN2A |
| 5.703e-03 | -5.17 | skin-upper_arm-malignant_melanoma-superficial_spreading | COSMIC cancer mutations | skin-upper_arm-malignant_melanoma-superficial_spreading | 6 | 4 | 17385 | 2587 |
KRAS,NRAS,HRAS,CDKN2A |
| 5.703e-03 | -5.17 | lung-left_lower_lobe-carcinoma-squamous_cell_carcinoma | COSMIC cancer mutations | lung-left_lower_lobe-carcinoma-squamous_cell_carcinoma | 6 | 4 | 17385 | 2587 |
KRAS,NRAS,HRAS,CDKN2A |
| 5.703e-03 | -5.17 | skin-malignant_melanoma-in_situ_melanotic_neoplasm | COSMIC cancer mutations | skin-malignant_melanoma-in_situ_melanotic_neoplasm | 6 | 4 | 17385 | 2587 |
KRAS,NRAS,HRAS,CDKN2A |
| 5.703e-03 | -5.17 | skin-abdomen-other-seborrhoeic_keratosis | COSMIC cancer mutations | skin-abdomen-other-seborrhoeic_keratosis | 6 | 4 | 17385 | 2587 |
FGFR3,PTEN,HRAS,PTPN11 |
| 5.703e-03 | -5.17 | skin-lower_leg-epidermal_nevus | COSMIC cancer mutations | skin-lower_leg-epidermal_nevus | 6 | 4 | 17385 | 2587 |
FGFR3,KRAS,NRAS,HRAS |
| 5.703e-03 | -5.17 | skin-adnexal_tumour-trichoblastoma | COSMIC cancer mutations | skin-adnexal_tumour-trichoblastoma | 6 | 4 | 17385 | 2587 |
FGFR3,KRAS,NRAS,HRAS |
| 5.703e-03 | -5.17 | thyroid-chronic_thyroiditis-Hashimotos_thyroiditis | COSMIC cancer mutations | thyroid-chronic_thyroiditis-Hashimotos_thyroiditis | 6 | 4 | 17385 | 2587 |
KRAS,NRAS,CCDC6,HRAS |
| 5.703e-03 | -5.17 | salivary_gland-head_neck-carcinoma-adenoid_cystic_carcinoma | COSMIC cancer mutations | salivary_gland-head_neck-carcinoma-adenoid_cystic_carcinoma | 6 | 4 | 17385 | 2587 |
KRAS,NRAS,HRAS,CDKN2A |
| 5.703e-03 | -5.17 | TSH | COSMIC cancer mutations | TSH | 6 | 4 | 17385 | 2587 |
GNAS,CDKN2C,MEN1,CDKN2A |
| 5.703e-03 | -5.17 | Hashimotos_thyroiditis | COSMIC cancer mutations | Hashimotos_thyroiditis | 6 | 4 | 17385 | 2587 |
KRAS,NRAS,CCDC6,HRAS |
| 5.703e-03 | -5.17 | skin-lower_back-other-seborrhoeic_keratosis | COSMIC cancer mutations | skin-lower_back-other-seborrhoeic_keratosis | 6 | 4 | 17385 | 2587 |
FGFR3,PTEN,HRAS,PTPN11 |
| 5.703e-03 | -5.17 | soft_tissue-striated_muscle-rhabdomyosarcoma-mixed | COSMIC cancer mutations | soft_tissue-striated_muscle-rhabdomyosarcoma-mixed | 6 | 4 | 17385 | 2587 |
KRAS,EWSR1,NRAS,HRAS |
| 5.703e-03 | -5.17 | epithelial_hyperplasia | COSMIC cancer mutations | epithelial_hyperplasia | 6 | 4 | 17385 | 2587 |
KRAS,NRAS,HRAS,CDKN2A |
| 5.703e-03 | -5.17 | central_nervous_system-cerebrum-glioma-astrocytoma_Grade_I | COSMIC cancer mutations | central_nervous_system-cerebrum-glioma-astrocytoma_Grade_I | 6 | 4 | 17385 | 2587 |
KRAS,NRAS,HRAS,PTPN11 |
| 5.703e-03 | -5.17 | skin-benign_melanocytic_nevus-dysplastic | COSMIC cancer mutations | skin-benign_melanocytic_nevus-dysplastic | 6 | 4 | 17385 | 2587 |
KRAS,NRAS,HRAS,CDKN2A |
| 5.703e-03 | -5.17 | skin-upper_leg-other-seborrhoeic_keratosis | COSMIC cancer mutations | skin-upper_leg-other-seborrhoeic_keratosis | 6 | 4 | 17385 | 2587 |
FGFR3,PTEN,HRAS,PTPN11 |
| 5.703e-03 | -5.17 | pituitary-adenoma-TSH | COSMIC cancer mutations | pituitary-adenoma-TSH | 6 | 4 | 17385 | 2587 |
GNAS,CDKN2C,MEN1,CDKN2A |
| 5.703e-03 | -5.17 | pancreas-carcinoid-endocrine_tumour-somatostatinoma | COSMIC cancer mutations | pancreas-carcinoid-endocrine_tumour-somatostatinoma | 6 | 4 | 17385 | 2587 |
GNAS,KRAS,NRAS,MEN1 |
| 5.703e-03 | -5.17 | in_situ_melanotic_neoplasm | COSMIC cancer mutations | in_situ_melanotic_neoplasm | 6 | 4 | 17385 | 2587 |
KRAS,NRAS,HRAS,CDKN2A |
| 5.703e-03 | -5.17 | somatostatinoma | COSMIC cancer mutations | somatostatinoma | 6 | 4 | 17385 | 2587 |
GNAS,KRAS,NRAS,MEN1 |
| 5.703e-03 | -5.17 | skin-benign_melanocytic_nevus-lentiginous_nevus | COSMIC cancer mutations | skin-benign_melanocytic_nevus-lentiginous_nevus | 6 | 4 | 17385 | 2587 |
FGFR3,KRAS,NRAS,HRAS |
| 5.705e-03 | -5.17 | CROONQUIST_NRAS_VS_STROMAL_STIMULATION_DN | MSigDB lists | CROONQUIST_NRAS_VS_STROMAL_STIMULATION_DN | 99 | 25 | 17377 | 2626 |
IER2,TK1,NASP,FOXM1,TSC22D3,RAD51AP1,PTTG1,TPX2,MKI67,ITM2A,PTP4A3,CDC6,KIF2C,AURKB,CCNF,MCM2,CCNB1,STMN1,SLC20A1,CCNA2,H2AFX,ZMIZ1,CD81,UBE2C,CCNB2 |
| 5.738e-03 | -5.16 | GO_NUCLEIC_ACID_PHOSPHODIESTER_BOND_HYDROLYSIS | MSigDB lists | GO_NUCLEIC_ACID_PHOSPHODIESTER_BOND_HYDROLYSIS | 233 | 50 | 17377 | 2626 |
CHD1L,PMS2,TATDN3,SND1,PARN,RRP36,EDC3,RPA2,PCNA,EXOSC7,PPP1R8,PELO,RNASEK,POP7,XPA,DCP1A,RNASEH2A,CNOT6L,ERI3,GTF2H2,N4BP2,OGG1,CSTF1,RPP25,TDP1,ERCC1,RFC3,RNASEH2C,POLK,RBX1,EXOSC9,DCLRE1C,RFC2,RPSA,RPA1,UTP20,KPNA1,POLE,RPS27A,DGCR8,TATDN2,AEN,HMGB2,CNOT6,RNASEL,TATDN1,RRS1,GEN1,TSEN15,DDB1 |
| 5.738e-03 | -5.16 | REACTOME_METABOLISM_OF_CARBOHYDRATES | MSigDB lists | REACTOME_METABOLISM_OF_CARBOHYDRATES | 233 | 50 | 17377 | 2626 |
GALK1,NUP188,GXYLT1,UGP2,AGRN,B4GALT5,RAE1,MDH2,SLC2A1,HEXB,TKT,SDC2,NUP54,SLC25A12,B4GALT1,GYG1,B4GALT4,PRKACA,EXT2,NUP205,GNS,CALM2,NUP210,GOT2,NUP107,NUP153,TALDO1,PHKG2,NUP85,SEH1L,SLC25A1,ABCC5,B3GALT6,PFKFB3,NUP155,PPP2CA,SGSH,PRPS2,NAGLU,NUP62,MDH1,ST3GAL2,GPI,B4GALT3,HEXA,PGAM1,CHPF2,PFKP,AAAS,B4GALT2 |
| 5.741e-03 | -5.16 | GSE24292_WT_VS_PPARG_KO_MACROPHAGE_UP | MSigDB lists | GSE24292_WT_VS_PPARG_KO_MACROPHAGE_UP | 189 | 42 | 17377 | 2626 |
MIF,TMBIM4,WDYHV1,UBXN1,FLOT1,STARD7,SLC29A1,FKBP2,RLF,APP,HOMER1,MLX,TNFAIP8,LRRC8D,CNPY4,FOXN2,RNF19A,ABCC5,FDFT1,TIMM8B,NSDHL,VHL,AACS,PPP1R21,ACSL3,ATP2C1,MKI67,LDHA,ABHD11,KDM3A,BSDC1,FAS,DNAJC10,MAGT1,NFIL3,PRDX5,NDUFA11,PPP3R1,E2F1,SLC16A1,GAS2,ABCA1 |
| 5.741e-03 | -5.16 | ACTGAAA,MIR-30A-3P,MIR-30E-3P | MSigDB lists | ACTGAAA,MIR-30A-3P,MIR-30E-3P | 189 | 42 | 17377 | 2626 |
BCCIP,CDC40,MECP2,PRKAA1,KIAA0232,DBF4,C5orf30,PAIP2,SAP130,LHX8,PTEN,SIAH1,SRSF4,AP2B1,TNPO3,ARID4A,CSNK1G3,SRSF10,SP3,CYTH1,ERMP1,ATXN1,KRAS,BRCA1,PBRM1,MEF2D,GALNT7,FXR1,AP4E1,ZFAND5,SH3GLB1,OSBPL11,ATP1A1,CCDC6,RBMX,MAPK6,TFDP1,VCPIP1,TOB1,PURA,SLC25A33,RAD51D |
| 5.741e-03 | -5.16 | GSE17721_0.5H_VS_12H_CPG_BMDC_DN | MSigDB lists | GSE17721_0.5H_VS_12H_CPG_BMDC_DN | 189 | 42 | 17377 | 2626 |
HSPH1,PARP12,AGRN,TM9SF4,AGTRAP,PHF23,FAM53C,FAM129A,PTTG1,TAP1,VTI1A,SIKE1,ZADH2,FAM8A1,RBM4,SLC25A37,SPPL2A,C18orf32,EIF2S2,CREB1,RNF135,SGCB,UBE2M,ACSL5,ENPP4,ADAM17,BIRC3,TMEM39A,NCK1,LYRM1,RDH10,CAMSAP1,RFFL,SLC25A22,DNAJA1,RAB1A,MTHFD2,DGCR8,SOCS4,CHPT1,ZNF598,ABCA1 |
| 5.741e-03 | -5.16 | GSE17580_TREG_VS_TEFF_DN | MSigDB lists | GSE17580_TREG_VS_TEFF_DN | 189 | 42 | 17377 | 2626 |
WASF2,SLC12A7,ARID2,DAP,MANBA,SCYL1,STARD7,ATG2B,THRAP3,APP,CSDE1,ATP6V0B,PRKD3,RAB8A,INTS7,RALB,NUP153,TAGLN2,NAP1L4,PTPRK,MLST8,RBM15B,CPNE1,ETV3,EMB,TANC1,TOLLIP,STK17B,MFN2,PLD3,PEX5,CDCA4,PDLIM1,STK38,AXIN1,SETD3,MAP4,ZNF436,APPL2,RNF38,LONP2,NUDT3 |
| 5.741e-03 | -5.16 | GSE24574_BCL6_LOW_TFH_VS_NAIVE_CD4_TCELL_UP | MSigDB lists | GSE24574_BCL6_LOW_TFH_VS_NAIVE_CD4_TCELL_UP | 189 | 42 | 17377 | 2626 |
SEPHS2,SRSF6,PTTG1,CDK2AP2,TAP1,TMEM97,RGS2,PDXDC1,BCAT2,RBM17,TFAP4,PTEN,INPP5A,SIVA1,PPIL2,POP7,TIMELESS,TNPO2,NDUFS8,CYC1,MARCH2,GTF2H2,MICAL3,PPIF,AMPD2,LDB1,DNAJC9,MEN1,TXNL4A,ISG15,SH3BP5,SLC19A1,GALNT2,DBI,UHRF2,ARAP1,PPP6R2,TMEM159,H3F3A,PLOD3,CD81,RNF139 |
| 5.741e-03 | -5.16 | GSE45365_HEALTHY_VS_MCMV_INFECTION_CD8A_DC_DN | MSigDB lists | GSE45365_HEALTHY_VS_MCMV_INFECTION_CD8A_DC_DN | 189 | 42 | 17377 | 2626 |
CDS2,PLAGL2,BRAP,RRAGC,CHIC2,FOXO3,TFRC,CFLAR,CD59,VAV1,RAB21,MED8,SP100,SAR1A,ATP13A3,ZCCHC2,AKR1B1,RNF19A,TALDO1,ASB6,CGGBP1,HNRNPM,NUDC,CDC37,PPP3CA,FAM49B,ELL2,PRPF3,ICAM2,LUC7L,DDX39A,DHX15,RHEB,PAF1,KEAP1,CORO1C,TICAM1,NCOA1,PDXK,H3F3A,ZC3HAV1,NXT2 |
| 5.741e-03 | -5.16 | GSE1432_CTRL_VS_IFNG_6H_MICROGLIA_DN | MSigDB lists | GSE1432_CTRL_VS_IFNG_6H_MICROGLIA_DN | 189 | 42 | 17377 | 2626 |
DDX58,KARS,CYLD,PARP12,HLA-E,TAP1,LAMTOR3,TIA1,MED13L,POMP,LYN,CTNNBL1,SAR1A,RALB,ATG3,RBM34,SRI,MVP,STAT3,PPA1,ZNF672,CNTN5,TRAFD1,RHOBTB3,KIAA0040,LAP3,TMEM126B,DNAJA1,PRPF3,PSMB9,ISG15,RHBDF2,KIF2A,TRIM26,MTHFD2,CERS6,HNRNPR,STAT6,STAT1,RBMS1,APOL2,RNF114 |
| 5.741e-03 | -5.16 | GSE339_CD8POS_VS_CD4CD8DN_DC_UP | MSigDB lists | GSE339_CD8POS_VS_CD4CD8DN_DC_UP | 189 | 42 | 17377 | 2626 |
SLC12A7,CASP6,TAP1,RRAGC,ASAH1,AGPAT3,POMP,OAT,BRIX1,SYNRG,REEP5,HDDC2,PHC2,CSDE1,GNS,FKBP1A,DNAJC8,NEK6,UCHL5,ATG13,RPN2,CYB5R1,NDUFA3,PDCL3,SLC25A1,ALDH9A1,LAP3,GORASP2,CYFIP2,KRTCAP2,ODC1,MAT2A,AMZ2,NUCB1,HSPA4,POLR2J,TXNDC16,SEC61A1,ACYP1,TMEM159,RPS6KC1,VPS29 |
| 5.741e-03 | -5.16 | GSE11961_MARGINAL_ZONE_BCELL_VS_MEMORY_BCELL_DAY7_UP | MSigDB lists | GSE11961_MARGINAL_ZONE_BCELL_VS_MEMORY_BCELL_DAY7_UP | 189 | 42 | 17377 | 2626 |
FGFR1OP,MAX,TRIP10,TOR3A,MAGED1,VTI1A,AGPAT3,ATG2B,AP1B1,LRRC14,HERC3,INPP5A,ATP13A3,CTR9,CDC25B,MINPP1,ABI1,FGFR1OP2,SRSF10,TDP1,ZNF524,TIMMDC1,KAT7,EZR,SLC25A22,DCUN1D5,EAF2,ZP3,TXNL4A,ERC1,GALNT2,WDR11,ERGIC3,ARAP1,LRPPRC,MBOAT1,SAMD8,ATF6,ROCK1,CCDC125,SMURF1,ANAPC4 |
| 5.741e-03 | -5.16 | GSE37301_LYMPHOID_PRIMED_MPP_VS_COMMON_LYMPHOID_PROGENITOR_DN | MSigDB lists | GSE37301_LYMPHOID_PRIMED_MPP_VS_COMMON_LYMPHOID_PROGENITOR_DN | 189 | 42 | 17377 | 2626 |
OTUD5,USP7,NUP188,MRPL42,SRGN,UCK2,FLOT1,CCNL2,CRLF3,CRKL,PHC2,PTPN2,SLC1A4,ZNF639,MBD2,MSH2,TRA2B,METTL9,GNAI2,SAMD4B,YTHDC1,RPAP3,NTPCR,NXT1,RBX1,SELPLG,EZR,RAB3IP,OGFR,MPG,LY6E,MARK2,TRIM47,MTHFD2,CCDC86,NIP7,DCK,HIPK2,GADD45B,GLG1,CHMP4B,TSEN15 |
| 5.759e-03 | -5.16 | Metal_Hydrolase | interpro domains | IPR032466 | 24 | 9 | 18492 | 2768 |
AMPD2,ADA2,DPYSL2,PTER,TATDN2,TATDN3,AMDHD2,TATDN1,DPYSL3 |
| 5.764e-03 | -5.16 | Surp | pfam domains | PF01805 | 6 | 4 | 17054 | 2545 |
SUGP1,CHERP,U2SURP,SUGP2 |
| 5.764e-03 | -5.16 | E2F_CC-MB | pfam domains | PF16421 | 6 | 4 | 17054 | 2545 |
E2F2,E2F4,E2F1,E2F3 |
| 5.764e-03 | -5.16 | TFIIS_C | pfam domains | PF01096 | 6 | 4 | 17054 | 2545 |
POLR2I,TCEA1,ZNRD1,POLR3K |
| 5.764e-03 | -5.16 | DIX | pfam domains | PF00778 | 6 | 4 | 17054 | 2545 |
DVL1,AXIN1,DVL2,AXIN2 |
| 5.764e-03 | -5.16 | EFG_C | pfam domains | PF00679 | 6 | 4 | 17054 | 2545 |
EFL1,GUF1,GFM2,EFTUD2 |
| 5.767e-03 | -5.16 | Cct4 (chaperonin containing Tcp1, subunit 4 (delta)) | protein interactions | 12464 | 47 | 15 | 17029 | 2761 |
DTL,RFWD3,CCT2,DPM1,PTEN,INTS7,VAV2,PPP6C,PIAS2,IGBP1,CCT8,GNB2,PDCL3,MLST8,CSTF1 |
| 5.767e-03 | -5.16 | TRMT6 (tRNA methyltransferase 6) | protein interactions | 51605 | 47 | 15 | 17029 | 2761 |
HHEX,EPRS,DUS3L,HNRNPR,QARS,CUL3,DNAJC17,DCP1A,CBWD1,DDX5,TTC4,ATP6V1B2,OGFR,NMD3,CAND1 |
| 5.767e-03 | -5.16 | RBM26 (RNA binding motif protein 26) | protein interactions | 64062 | 47 | 15 | 17029 | 2761 |
RPA2,RB1,KBTBD7,CERK,ATXN1,CRCP,JMJD6,YWHAZ,KIFAP3,PRPF3,RNF26,LUC7L,CDKN2A,MAPK3,RPA1 |
| 5.767e-03 | -5.16 | VAMP4 (vesicle associated membrane protein 4) | protein interactions | 8674 | 47 | 15 | 17029 | 2761 |
PLK1,NAPG,SNAP29,SNAP23,MBLAC2,STX18,SCFD2,VPS45,AP1M1,VTI1A,CSNK2A1,PACS1,STX16,GOSR1,LMNA |
| 5.767e-03 | -5.16 | SEPT11 (septin 11) | protein interactions | 55752 | 47 | 15 | 17029 | 2761 |
CDK5,SEPT1,SEC23IP,SEPT9,SUCLG1,MRPL12,NABP2,VDAC2,SEPT8,TCOF1,SEPT7,TOMM40,TMEM9,SCYL2,SH3GLB1 |
| 5.767e-03 | -5.16 | SSFA2 (sperm specific antigen 2) | protein interactions | 6744 | 47 | 15 | 17029 | 2761 |
DNAJC10,MAPRE1,PCM1,PTEN,RAB7A,MYO18A,MYH9,YWHAZ,BRCA1,CAPZA2,ANLN,SGF29,LUC7L2,IFI16,MASTL |
| 5.767e-03 | -5.16 | MRPL49 (mitochondrial ribosomal protein L49) | protein interactions | 740 | 47 | 15 | 17029 | 2761 |
MRPL50,COX15,MRPL9,CYLD,MRPL42,MRPL39,TCF3,MRPL12,CUL3,CUL1,KRAS,NENF,MCM2,APP,CAND1 |
| 5.771e-03 | -5.15 | cyclin-dependent protein kinase activity | molecular function | GO:0097472 | 36 | 12 | 17224 | 2647 |
CCNK,CDK5,CCNA2,CDKN1B,CDK13,CDK11B,CCNB1,CCNB2,CDK2,CDK11A,CDK12,PRPF4B |
| 5.785e-03 | -5.15 | NING_CHRONIC_OBSTRUCTIVE_PULMONARY_DISEASE_UP | MSigDB lists | NING_CHRONIC_OBSTRUCTIVE_PULMONARY_DISEASE_UP | 146 | 34 | 17377 | 2626 |
RPS15,FEZ2,HLA-E,B4GALT5,SRSF6,CLCC1,NCKAP1,BCAP31,RPL23A,WWP2,SAR1A,TRA2B,GPX4,TGFB1,GCC2,TRIM8,MAPKAPK3,ILF3,OGDH,EDF1,SEPT7,MBD3,MAT2A,EIF3K,EPRS,SERF2,CSK,RPLP1,PKD2,H3F3A,SNRNP70,SLC25A39,DDX52,SSRP1 |
| 5.790e-03 | -5.15 | MAVS (mitochondrial antiviral signaling protein) | protein interactions | 57506 | 88 | 24 | 17029 | 2761 |
DDX58,PLK1,MIB2,BIRC3,UBXN1,IRF3,UBE4A,WDR5,SPPL2B,BIRC2,BZW2,IRF5,FADD,MFN2,KRR1,STAT1,TICAM1,MAVS,TRAF5,SMURF1,PCBP2,RNF5,TRIM14,RNF114 |
| 5.790e-03 | -5.15 | TTC1 (tetratricopeptide repeat domain 1) | protein interactions | 7265 | 88 | 24 | 17029 | 2761 |
HARS,UBXN1,SIKE1,UBQLN2,XPO7,QSOX2,EVC2,SRXN1,GNAS,HSPA4,INPP5A,EFTUD2,PPM1G,CRY2,ZRANB2,PPP6R2,TTLL12,NDE1,AHCYL1,PDIA6,GNAI2,HRAS,CBX4,SSSCA1 |
| 5.800e-03 | -5.15 | GO_RIBONUCLEOPROTEIN_COMPLEX_BINDING | MSigDB lists | GO_RIBONUCLEOPROTEIN_COMPLEX_BINDING | 89 | 23 | 17377 | 2626 |
SRP72,EIF5A,DHX29,OLA1,LETMD1,SECISBP2,EIF2A,EIF4H,ABCF1,RPSA,PHF6,EIF3K,SEC61A1,EIF4A3,NVL,PQBP1,PRMT7,RPN2,RNASEL,RNF135,CPEB2,NMD3,TIMM50 |
| 5.800e-03 | -5.15 | positive regulation of transcription by RNA polymerase II | biological process | GO:0045944 | 1129 | 202 | 17256 | 2622 |
RORB,ZBED3,CCNC,ZNF76,IER2,H2AFZ,AGRN,AAMDC,HEXB,CCNL2,SIRT2,MAPK14,PARK7,GLMP,CREM,TET3,USF1,GLIS2,ZNF639,ETV6,PIK3R2,ECD,MYBL1,SENP1,ARID4A,CARM1,CDC5L,SP3,KLF10,AATF,NCK1,GABPA,LRP5,EAF2,BRCA1,SOX4,CBFB,ARF4,DOT1L,PAF1,HHEX,SMAD2,RPS27A,E2F4,OGT,ZNF268,RNASEL,TFDP2,SMAD1,E2F2,PSMC1,HDAC2,ZNF564,DDX58,HSPH1,PPP1R12A,DHX9,CHCHD2,MEF2A,CDK13,EZH1,THRAP3,PPP3CB,RLF,ASXL2,CRLF3,CDC73,DDRGK1,TFAP4,SUB1,RB1,MLX,NFATC3,MED10,SSBP3,ZNF746,CTR9,YBX1,MYDGF,MAML1,ERLIN1,MTA2,LDB1,MYBL2,EXOSC9,RTF1,EIF2A,NFATC2IP,ADRB2,ELK1,KDM3A,IRF5,PSMC4,CAND1,RXRB,ETS2,SETD3,RBMX,PIAS2,NLRC5,PPP3R1,TBPL1,CEBPG,RUVBL2,YY1,EGLN1,TCF12,ASH1L,FOXM1,RPS6KA1,RAF1,SMARCA4,PLAGL2,IRF3,PCBP1,APP,NRF1,PIN1,LPIN2,GMEB1,TARDBP,MAVS,ATF2,RBM15,CDK12,RPRD1B,MOSPD1,POU2AF1,BRD4,KAT7,E2F3,WBP2,NFATC2,MEF2D,TRIM28,DDX17,SUPT16H,TAF2,VEZF1,RBL1,SCAP,SAFB,HIPK2,STAT6,ARNTL,STAT1,ATF6,NCOA1,AKNA,SMAD4,POU3F2,SLC30A9,BCL2L12,EYA1,TCF3,AGO2,KLF13,NKRF,HMGN3,ABHD14B,WDR5,ETS1,PAGR1,FOXO3,WWP2,GTF2F1,CCNK,IRF4,PRDM4,ARHGEF2,SS18L1,CARF,CITED2,CREB1,STAT3,NCOA2,TGFB1,PPP3CA,DCAF6,KAT2A,PRKDC,RFXANK,MEN1,KLF6,FADD,MAPK3,TFEB,ATAD2,GPS2,TFE3,PITX1,TFDP1,E2F1,PML,HMGB2,PKD2,RBPJ,ZMIZ1,CD81,USF2,HRAS,IFI16 |
| 5.803e-03 | -5.15 | REACTOME_CONVERSION_FROM_APC_C_CDC20_TO_APC_C_CDH1_IN_LATE_ANAPHASE | MSigDB lists | REACTOME_CONVERSION_FROM_APC_C_CDC20_TO_APC_C_CDH1_IN_LATE_ANAPHASE | 16 | 7 | 17377 | 2626 |
ANAPC2,ANAPC7,CDC16,CDC23,CDC27,UBE2C,ANAPC4 |
| 5.803e-03 | -5.15 | GO_BLASTOCYST_GROWTH | MSigDB lists | GO_BLASTOCYST_GROWTH | 16 | 7 | 17377 | 2626 |
GINS1,CTR9,RTF1,PALB2,ZNF830,GINS4,PRPF19 |
| 5.803e-03 | -5.15 | REACTOME_PRE_NOTCH_PROCESSING_IN_GOLGI | MSigDB lists | REACTOME_PRE_NOTCH_PROCESSING_IN_GOLGI | 16 | 7 | 17377 | 2626 |
B4GALT1,RAB6A,NOTCH2,ATP2A2,TMED2,SEL1L,MFNG |
| 5.803e-03 | -5.15 | GO_MICROTUBULE_PLUS_END | MSigDB lists | GO_MICROTUBULE_PLUS_END | 16 | 7 | 17377 | 2626 |
DST,KIF2C,MAPRE2,MAPRE1,KIF18B,MYO5A,SPAG5 |
| 5.803e-03 | -5.15 | GO_U5_SNRNP | MSigDB lists | GO_U5_SNRNP | 16 | 7 | 17377 | 2626 |
SNRNP200,SNRPG,SNRPD3,TXNL4A,SNRPB,PRPF18,DDX23 |
| 5.803e-03 | -5.15 | GALE_APL_WITH_FLT3_MUTATED_DN | MSigDB lists | GALE_APL_WITH_FLT3_MUTATED_DN | 16 | 7 | 17377 | 2626 |
HLA-B,NAPG,NDUFV1,ARF1,DRAP1,PQBP1,GPR137 |
| 5.803e-03 | -5.15 | GO_MAGNESIUM_ION_TRANSMEMBRANE_TRANSPORTER_ACTIVITY | MSigDB lists | GO_MAGNESIUM_ION_TRANSMEMBRANE_TRANSPORTER_ACTIVITY | 16 | 7 | 17377 | 2626 |
NIPAL3,NIPA2,MAGT1,SLC41A1,NIPA1,MRS2,ZDHHC13 |
| 5.803e-03 | -5.15 | LUND_SILENCED_BY_METHYLATION | MSigDB lists | LUND_SILENCED_BY_METHYLATION | 16 | 7 | 17377 | 2626 |
ADAM17,CLU,TIMP2,TMEM101,H3F3A,ODC1,AMD1 |
| 5.803e-03 | -5.15 | GO_MAGNESIUM_ION_TRANSMEMBRANE_TRANSPORT | MSigDB lists | GO_MAGNESIUM_ION_TRANSMEMBRANE_TRANSPORT | 16 | 7 | 17377 | 2626 |
NIPAL3,NIPA2,MAGT1,SLC41A1,NIPA1,MRS2,ZDHHC13 |
| 5.803e-03 | -5.15 | GO_POSITIVE_REGULATION_OF_MRNA_3_END_PROCESSING | MSigDB lists | GO_POSITIVE_REGULATION_OF_MRNA_3_END_PROCESSING | 16 | 7 | 17377 | 2626 |
PAF1,POLR2G,CCNB1,BTG2,TOB1,PABPC1,CDC73 |
| 5.804e-03 | -5.15 | CASORELLI_APL_SECONDARY_VS_DE_NOVO_DN | MSigDB lists | CASORELLI_APL_SECONDARY_VS_DE_NOVO_DN | 9 | 5 | 17377 | 2626 |
RPLP2,RPL27A,RBM38,EEF1D,RPL38 |
| 5.804e-03 | -5.15 | REACTOME_NEF_MEDIATED_DOWNREGULATION_OF_MHC_CLASS_I_COMPLEX_CELL_SURFACE_EXPRESSION | MSigDB lists | REACTOME_NEF_MEDIATED_DOWNREGULATION_OF_MHC_CLASS_I_COMPLEX_CELL_SURFACE_EXPRESSION | 9 | 5 | 17377 | 2626 |
AP1S1,PACS1,AP1B1,HLA-A,AP1M1 |
| 5.804e-03 | -5.15 | SEMBA_FHIT_TARGETS_DN | MSigDB lists | SEMBA_FHIT_TARGETS_DN | 9 | 5 | 17377 | 2626 |
BIRC5,CLN6,ASPM,SPAG5,CENPF |
| 5.807e-03 | -5.15 | REACTOME_INSULIN_RECEPTOR_SIGNALLING_CASCADE | MSigDB lists | REACTOME_INSULIN_RECEPTOR_SIGNALLING_CASCADE | 84 | 22 | 17377 | 2626 |
PDPK1,PRKAB1,NRAS,TSC2,AKT2,RAF1,PRKAA1,KRAS,PDE3B,MAP2K2,RHEB,MAPK3,EEF2K,TSC1,FGFR3,SHC1,PIK3R2,CAB39,STK11,MAPK1,HRAS,MLST8 |
| 5.817e-03 | -5.15 | DICER1 (dicer 1, ribonuclease III) | protein interactions | 23405 | 74 | 21 | 17029 | 2761 |
USP7,TRIM41,RPS2,AGO2,MTFR2,MEMO1,DHX9,CUL3,GTPBP4,RPL15,DDX20,PRKRA,MAD2L2,USF1,TIMM13,SYNCRIP,STRBP,CRY2,GEMIN4,CFAP20,ZMAT3 |
| 5.817e-03 | -5.15 | QKI (QKI, KH domain containing RNA binding) | protein interactions | 9444 | 74 | 21 | 17029 | 2761 |
EWSR1,RBM42,TRIM11,ATXN1,NDUFA7,DUSP22,PCBP1,APP,SNRPA,POLR2A,OIP5,RBM23,SERF2,SYNCRIP,MED10,RBMX,MED15,NABP1,ATE1,CARM1,PCBP2 |
| 5.817e-03 | -5.15 | ZPR1 (ZPR1 zinc finger) | protein interactions | 8882 | 74 | 21 | 17029 | 2761 |
UBQLN4,CDC123,UFC1,ACTR3,UBXN1,HNRNPF,AGFG1,UBE4B,ATP6V1B2,STAM,SRXN1,ABHD5,FKBP1A,SNUPN,HSPBP1,PPME1,OGT,AHCYL1,RPRD1B,SSSCA1,SZRD1 |
| 5.817e-03 | -5.15 | SUMO3 (small ubiquitin-like modifier 3) | protein interactions | 6612 | 74 | 21 | 17029 | 2761 |
TK1,MAPRE1,EWSR1,MAPKAPK3,DRAP1,CUL3,RANGAP1,FKBP2,BLM,UBE2I,CHAF1A,RAD23A,SP100,HIPK2,RAD23B,PML,PIAS2,UPF2,TAGLN2,TP53BP2,SENP1 |
| 5.817e-03 | -5.15 | STK26 (serine/threonine kinase 26) | protein interactions | 51765 | 74 | 21 | 17029 | 2761 |
MOB4,STRIP1,DYNLL1,RAF1,UBXN1,TAOK1,CCM2,STRN4,SIKE1,RGS2,TWF2,APP,MCTS1,CAPN2,PPP2CA,PDCD10,GOLGA2,ATIC,TTC4,FGFR1OP2,DCTN1 |
| 5.817e-03 | -5.15 | SH3GL1 (SH3 domain containing GRB2 like 1, endophilin A2) | protein interactions | 6455 | 74 | 21 | 17029 | 2761 |
TP53RK,PDCD6IP,EWSR1,LAP3,ACTR3,NSUN2,SEPT8,ARPC1A,PRKACA,SH3GLB1,RPA1,PFDN5,ARPC5,AXIN1,MTA1,PML,SH3GLB2,IMPDH1,YWHAZ,SGF29,FUBP1 |
| 5.817e-03 | -5.15 | MCRS1 (microspherule protein 1) | protein interactions | 10445 | 74 | 21 | 17029 | 2761 |
NOP2,MRPS15,GPBP1L1,NFATC2,BRCA1,INO80E,BLM,PHC2,UBTF,PCM1,PTEN,LSM6,UCHL5,TULP3,ZBTB22,RUVBL2,YY1,FBL,MAP3K5,GCC1,DVL2 |
| 5.831e-03 | -5.14 | Znf_TFIIS | interpro domains | IPR001222 | 6 | 4 | 18492 | 2768 |
POLR2I,TCEA1,ZNRD1,POLR3K |
| 5.831e-03 | -5.14 | SWAP/Surp_sf | interpro domains | IPR035967 | 6 | 4 | 18492 | 2768 |
SUGP1,CHERP,SUGP2,U2SURP |
| 5.831e-03 | -5.14 | DIX | interpro domains | IPR001158 | 6 | 4 | 18492 | 2768 |
DVL1,AXIN1,DVL2,AXIN2 |
| 5.831e-03 | -5.14 | DIX_dom_sf | interpro domains | IPR038207 | 6 | 4 | 18492 | 2768 |
DVL1,AXIN1,DVL2,AXIN2 |
| 5.831e-03 | -5.14 | E2F_CC-MB | interpro domains | IPR032198 | 6 | 4 | 18492 | 2768 |
E2F2,E2F4,E2F1,E2F3 |
| 5.831e-03 | -5.14 | EFG_V-like | interpro domains | IPR000640 | 6 | 4 | 18492 | 2768 |
EFL1,GUF1,GFM2,EFTUD2 |
| 5.831e-03 | -5.14 | EFG_III/V | interpro domains | IPR035647 | 6 | 4 | 18492 | 2768 |
EFL1,GUF1,GFM2,EFTUD2 |
| 5.831e-03 | -5.14 | Surp | interpro domains | IPR000061 | 6 | 4 | 18492 | 2768 |
SUGP1,CHERP,SUGP2,U2SURP |
| 5.831e-03 | -5.14 | Isoprenoid_synthase_dom_sf | interpro domains | IPR008949 | 6 | 4 | 18492 | 2768 |
NDUFAF6,GGPS1,PDSS2,FDFT1 |
| 5.842e-03 | -5.14 | soft_tissue-striated_muscle-rhabdoid_tumour | COSMIC cancer mutations | soft_tissue-striated_muscle-rhabdoid_tumour | 170 | 38 | 17385 | 2587 |
ZNF786,EWSR1,TSC2,NF1,SF3B1,SMARCA4,MYO9B,FGFR3,RB1,NVL,PTEN,ETV6,MSH2,PTPN11,MVP,MSH6,ABHD2,NRAS,GUK1,PRRC2A,VHL,TIGD5,MKI67,KRAS,BRCA1,PBRM1,MEN1,KMT2C,GNAS,CCDC6,AXIN1,PTPN7,KHSRP,DHTKD1,STK11,HRAS,SMAD4,CDKN2A |
| 5.842e-03 | -5.14 | rhabdoid_tumour | COSMIC cancer mutations | rhabdoid_tumour | 170 | 38 | 17385 | 2587 |
ZNF786,EWSR1,TSC2,NF1,SF3B1,SMARCA4,MYO9B,FGFR3,RB1,NVL,PTEN,ETV6,MSH2,PTPN11,MVP,MSH6,ABHD2,NRAS,GUK1,PRRC2A,VHL,TIGD5,MKI67,KRAS,BRCA1,PBRM1,MEN1,KMT2C,GNAS,CCDC6,AXIN1,PTPN7,KHSRP,DHTKD1,STK11,HRAS,SMAD4,CDKN2A |
| 5.862e-03 | -5.14 | Fas Ligand (FasL) pathway and Stress induction of Heat Shock Proteins (HSP) regulation | WikiPathways | WP314 | 44 | 14 | 5312 | 837 |
RB1,CASP6,MAPKAPK3,PRKDC,BCL2,ACTB,ARHGDIB,CYCS,LMNA,FADD,FAF1,CFLAR,FAS,SPTAN1 |
| 5.863e-03 | -5.14 | GO_TRANSFERASE_ACTIVITY_TRANSFERRING_PHOSPHORUS_CONTAINING_GROUPS | MSigDB lists | GO_TRANSFERASE_ACTIVITY_TRANSFERRING_PHOSPHORUS_CONTAINING_GROUPS | 940 | 170 | 17377 | 2626 |
CCNC,POLA2,FGFR1OP,HMGXB3,SNX15,CSNK2A1,NANS,CCNB1,CDIPT,MAPK14,POLR3K,PAPOLA,EEF2K,ABL2,CDK5,CALM2,NEK6,PIK3R2,UPRT,MAST2,ZNRD1,FGFR1OP2,CDC37,SRPK2,PLK3,PLK1,AKT2,PBK,TLK1,AURKB,PRPSAP1,STK17B,PRIM1,MAP3K4,MKNK1,LIMK1,BAZ1B,CRCP,CAB39,STK11,ROCK1,CHEK2,RNASEL,CHPT1,PFKP,SEPHS2,CTU2,PIGN,POLR2K,TRIO,PRKAA1,CERK,ADCK5,CDK13,EIF2AK4,CHKA,DAPK1,PIGG,PCYT2,PIKFYVE,ALDH18A1,N4BP2,PHKG2,CSNK1G3,TERF2,POLR2I,PRIM2,MAPKAPK3,PGS1,PIP4K2C,EIF2AK1,MAP4K3,MAP2K2,DAPK3,TWISTNB,MASTL,PI4K2A,POLR2J,UAP1,CSK,DCK,CSNK1G1,PRPS2,FN3KRP,MAP3K5,CDK2,CCNB2,NRBP1,PRKAB1,TP53RK,UGP2,RPS6KA1,RAF1,UCK2,UCK1,CHKB,ADPGK,LYN,PRKACA,CPNE3,FLAD1,VAV1,PRKD3,PDK2,CD3EAP,RPAP1,SCYL3,CDK12,ULK3,POLR2G,POLR2L,TAOK1,MAP4K4,POLR2D,PFKFB3,GALK2,PKMYT1,POLG2,TRIM28,JAK1,CLK3,STK38,FASTK,HIPK2,PDXK,MAPK1,CSNK1D,POLQ,PRPF4B,CMAS,GALK1,CDS2,SCYL1,GNE,IP6K2,CDK11B,PMVK,CSNK1A1,SCYL2,PIP4K2A,PIP5K1C,CCNK,FASTKD3,FGFR3,PTPN11,POLR1B,PTGES3,MAP3K14,GTF2H2,CAMK2G,PDPK1,CSNK1G2,TK1,GUK1,POLK,NEK7,PRKDC,POLR3GL,TBRG4,MARK2,CDK11A,POLR2A,MAPK3,NEK1,LTBP4,POLE,MAPK6,RPS6KC1,HIPK3,TERF1 |
| 5.873e-03 | -5.14 | GO_LUMENAL_SIDE_OF_MEMBRANE | MSigDB lists | GO_LUMENAL_SIDE_OF_MEMBRANE | 28 | 10 | 17377 | 2626 |
HLA-B,NUCB1,HLA-E,BDH1,CTSA,PKD2,BCAP31,SPPL2B,HLA-A,SPPL2A |
| 5.873e-03 | -5.14 | BIOCARTA_PYK2_PATHWAY | MSigDB lists | BIOCARTA_PYK2_PATHWAY | 28 | 10 | 17377 | 2626 |
CRKL,CALM2,SHC1,RAF1,RAC1,MAPK14,MAPK1,HRAS,MAP2K2,MAPK3 |
| 5.873e-03 | -5.14 | GO_RNA_POLYADENYLATION | MSigDB lists | GO_RNA_POLYADENYLATION | 28 | 10 | 17377 | 2626 |
PAF1,GRSF1,AHCYL1,SYMPK,CDC73,PABPC1,ZC3H3,APP,CSTF1,PAPOLA |
| 5.873e-03 | -5.14 | PID_BARD1_PATHWAY | MSigDB lists | PID_BARD1_PATHWAY | 28 | 10 | 17377 | 2626 |
UBE2D3,FANCL,EWSR1,PCNA,PRKDC,BRCA1,FANCE,CDK2,CSTF1,XRCC5 |
| 5.873e-03 | -5.14 | MODULE_281 | MSigDB lists | MODULE_281 | 28 | 10 | 17377 | 2626 |
RPA2,ARF5,PPP6C,GMFB,YBX1,PRPSAP1,ARF4,RPA1,FUBP1,RAD23A |
| 5.873e-03 | -5.14 | REACTOME_FORMATION_OF_THE_HIV1_EARLY_ELONGATION_COMPLEX | MSigDB lists | REACTOME_FORMATION_OF_THE_HIV1_EARLY_ELONGATION_COMPLEX | 28 | 10 | 17377 | 2626 |
CTDP1,POLR2I,POLR2G,POLR2L,POLR2J,POLR2K,POLR2D,GTF2H2,POLR2A,GTF2F1 |
| 5.873e-03 | -5.14 | GO_HSP70_PROTEIN_BINDING | MSigDB lists | GO_HSP70_PROTEIN_BINDING | 28 | 10 | 17377 | 2626 |
DNAJC10,DNAJC2,ST13,DNAJB2,CDKN1B,NUP62,DNAJB1,DNAJA1,CREB1,TFRC |
| 5.873e-03 | -5.14 | CHNG_MULTIPLE_MYELOMA_HYPERPLOID_DN | MSigDB lists | CHNG_MULTIPLE_MYELOMA_HYPERPLOID_DN | 28 | 10 | 17377 | 2626 |
RFWD3,SEC31A,FBXO21,COPA,SLBP,USP22,VPS4A,MCFD2,TMED2,NECAP2 |
| 5.884e-03 | -5.14 | MULLIGHAN_NPM1_MUTATED_SIGNATURE_1_UP | MSigDB lists | MULLIGHAN_NPM1_MUTATED_SIGNATURE_1_UP | 250 | 53 | 17377 | 2626 |
CLSPN,MPHOSPH8,RWDD1,ZNF768,UBR2,C5orf30,B4GALT4,DCUN1D4,CCDC28A,CFLAR,DST,TNS3,EXOSC7,CD3EAP,PPP1R8,TANK,PTPN11,PDS5B,GTSE1,FEM1B,KIF22,OSTF1,ZNF770,MTX2,NCOA2,SMC4,ADCY7,RYBP,SRPK2,CSTF1,PDPK1,SP3,VOPP1,HMGN5,CREG1,NEK7,CHMP2B,COMMD4,RHEB,MAN2A2,CAT,KPNA4,IDE,TBC1D17,FBXO28,RBM25,DCK,ST3GAL2,MAP3K5,TFDP2,CDK2,TMEM14A,PURA |
| 5.890e-03 | -5.13 | TORCHIA_TARGETS_OF_EWSR1_FLI1_FUSION_DN | MSigDB lists | TORCHIA_TARGETS_OF_EWSR1_FLI1_FUSION_DN | 295 | 61 | 17377 | 2626 |
MIF,UBE2E2,ZNF496,DNMT3A,PLXNC1,GMFG,ACAP1,PM20D2,DCUN1D4,CRLF3,LCLAT1,CPNE3,RSAD1,KIAA1147,FKBP1A,PRKD3,PDXP,TNS3,BRPF3,KLHL5,RALB,LRRC8D,RCSD1,H2AFY,SEPT11,KIFAP3,CNN2,TOP1MT,KCNAB2,TRIM14,SOCS5,RHOBTB3,PTPN18,ELL2,OAF,EMB,SELPLG,NQO2,MAP4K4,ITM2A,WIPF1,ATXN1,GALNT7,SOX4,CYFIP2,PSMB9,PDE3B,BBS12,ARHGAP15,MAN2A2,AGPAT2,PDLIM1,L3MBTL3,NLRC5,BCL7C,CCDC69,SLAIN1,FKBP5,PDXK,CD81,LRCH1 |
| 5.903e-03 | -5.13 | GSE32986_UNSTIM_VS_GMCSF_AND_CURDLAN_LOWDOSE_STIM_DC_DN | MSigDB lists | GSE32986_UNSTIM_VS_GMCSF_AND_CURDLAN_LOWDOSE_STIM_DC_DN | 173 | 39 | 17377 | 2626 |
ZNF76,KLHL21,ABCC10,SLC39A13,SUMF1,ATG2B,MXD4,XPNPEP3,ASXL2,IFT27,JMY,NFATC3,LRRC8D,RCSD1,BRI3,SLC38A10,PIK3IP1,CNOT6L,RNF135,SLC35C2,CNNM3,ATP6V0D1,CTDSP2,FAM171A1,PBXIP1,ATXN1,WDR81,AMDHD2,HERPUD2,EPB41,TRAM2,SGSH,SLC38A7,CHD3,EXOC4,CTSA,CLN3,HEXA,ATP6V0E1 |
| 5.903e-03 | -5.13 | GSE26928_NAIVE_VS_CXCR5_POS_CD4_TCELL_DN | MSigDB lists | GSE26928_NAIVE_VS_CXCR5_POS_CD4_TCELL_DN | 173 | 39 | 17377 | 2626 |
WSB2,PWWP2A,TXN,ABCC10,STARD7,KLHL18,RAB6A,PSEN1,SPPL2A,FERMT3,PRNP,GNS,SEC11A,DPYSL2,RABGAP1L,PHTF1,EXOSC1,RP2,NCOA2,EIF5A,FAM49B,POLK,KCTD20,AMDHD2,CHMP2B,HERPUD2,ODC1,ZFAND5,TAF2,ATP6V1D,ITPRIPL1,SURF4,SETD3,CORO1C,HAGHL,COX5A,NUP62,RBPJ,ZSWIM6 |
| 5.903e-03 | -5.13 | GSE12845_IGD_POS_BLOOD_VS_NAIVE_TONSIL_BCELL_UP | MSigDB lists | GSE12845_IGD_POS_BLOOD_VS_NAIVE_TONSIL_BCELL_UP | 173 | 39 | 17377 | 2626 |
KCTD7,EXOC3,GLT8D1,GGNBP2,PARP12,ABCC10,MXD4,RAB11A,CCDC28A,NPLOC4,ZNF428,CTSS,ZNF302,DPYSL2,MEGF8,KIFAP3,TAGLN2,MCPH1,TIMP2,HMGN4,KIAA0040,BTG2,TMEM147,FAM50B,ICAM2,PRMT2,CYB5A,RHOB,UBTF,PLD3,AHNAK,ETS2,TATDN2,TPP2,OGT,WDR7,ACBD4,PIEZO1,CD81 |
| 5.909e-03 | -5.13 | Pausing and recovery of Tat-mediated HIV elongation | REACTOME pathways | R-HSA-167238 | 38 | 13 | 10287 | 1696 |
CTDP1,POLR2I,POLR2J,POLR2G,POLR2L,POLR2K,ELOA,POLR2D,TCEA1,POLR2A,GTF2F1,SUPT16H,SSRP1 |
| 5.909e-03 | -5.13 | Tat-mediated HIV elongation arrest and recovery | REACTOME pathways | R-HSA-167243 | 38 | 13 | 10287 | 1696 |
CTDP1,POLR2I,POLR2J,POLR2G,POLR2L,POLR2K,ELOA,POLR2D,TCEA1,POLR2A,GTF2F1,SUPT16H,SSRP1 |
| 5.913e-03 | -5.13 | DYNLT1 (dynein light chain Tctex-type 1) | protein interactions | 6993 | 117 | 30 | 17029 | 2761 |
MAPRE2,TXN,ADD1,LUZP1,TCTEX1D2,DYNLL1,CUL3,ARGLU1,CDCA2,BLM,VDAC1,SYNRG,RAPGEF6,APP,LMNA,MASTL,SAP130,DST,ZBTB21,ADD3,CCP110,EXOC4,OGT,TP53BP2,DVL1,FAM208A,NRBP1,DVL2,DYNC1LI2,DCTN1 |
| 5.946e-03 | -5.13 | chromatin-mediated maintenance of transcription | biological process | GO:0048096 | 9 | 5 | 17256 | 2622 |
KMT2B,ARID1A,ARID1B,SMARCD1,ELOF1 |
| 5.946e-03 | -5.13 | positive regulation of chromosome separation | biological process | GO:1905820 | 9 | 5 | 17256 | 2622 |
RB1,ESPL1,NSMCE2,CDT1,CUL3 |
| 5.952e-03 | -5.12 | CLEC7A (Dectin-1) signaling | REACTOME pathways | R-HSA-5607764 | 101 | 27 | 10287 | 1696 |
PDPK1,PPP3CA,PSMA8,PSMB7,PSMA1,CUL1,UBE2V1,NFATC2,PPP3CB,PSMD9,PSMB9,PSMB3,PSMC4,CALM2,PSMD2,NFATC3,PSMA6,PSMD1,RPS27A,TAB2,PSMD8,PSMD3,PPP3R1,MAP3K14,AHCYL1,PSMC1,UBE2M |
| 5.966e-03 | -5.12 | THIOREDOXIN_2 | prosite domains | PS51352 | 35 | 11 | 12060 | 1670 |
DNAJC10,TXN,PRDX3,TMX4,PRDX5,TMX3,PDIA6,GLRX3,QSOX2,TMX1,PRDX1 |
| 5.980e-03 | -5.12 | PID_TGFBR_PATHWAY | MSigDB lists | PID_TGFBR_PATHWAY | 55 | 16 | 17377 | 2626 |
PDPK1,TGFB1,PPP2CA,FKBP1A,RHOA,SMAD2,SHC1,TAB2,AXIN1,PML,XIAP,EIF2A,ARRB2,SMURF1,SMAD4,STRAP |
| 5.985e-03 | -5.12 | positive regulation of transcription elongation from RNA polymerase II promoter | biological process | GO:0032968 | 16 | 7 | 17256 | 2622 |
PAF1,CTR9,RTF1,BRD4,CDC73,GTF2F1,SUPT16H |
| 5.985e-03 | -5.12 | mitotic chromosome condensation | biological process | GO:0007076 | 16 | 7 | 17256 | 2622 |
NUSAP1,SMC2,PHF23,NCAPG,AKAP8,CDCA5,SMC4 |
| 5.985e-03 | -5.12 | regulation of Arp2/3 complex-mediated actin nucleation | biological process | GO:0034315 | 16 | 7 | 17256 | 2622 |
ARFIP2,CYFIP1,ARF1,WAS,NCKAP1,GMFG,GMFB |
| 5.985e-03 | -5.12 | polyamine metabolic process | biological process | GO:0006595 | 16 | 7 | 17256 | 2622 |
SRM,DHPS,ODC1,OAZ1,SAT2,AMD1,OAZ2 |
| 5.993e-03 | -5.12 | BYSL (bystin like) | protein interactions | 705 | 122 | 31 | 17029 | 2761 |
NOP9,ZFP64,DHPS,FAM207A,SMARCA4,GMCL1,CDC23,PARN,KCMF1,TSR2,APP,PNO1,LMNA,DDX17,KRR1,PHC2,PTPN2,GOLGA2,L3MBTL3,CDCA7L,ZNF746,TNPO2,MRFAP1L1,FAU,FBL,SMURF1,RPS26,COIL,FTSJ3,IFI16,CSNK1D |
| 5.993e-03 | -5.12 | GSE9650_NAIVE_VS_MEMORY_CD8_TCELL_UP | MSigDB lists | GSE9650_NAIVE_VS_MEMORY_CD8_TCELL_UP | 184 | 41 | 17377 | 2626 |
SRM,CCDC93,DAP,TIA1,KIF23,BIRC2,PIP4K2A,CTSS,IL6ST,SLC44A1,MECR,BRD7,DCP1A,ANP32A,TTC3,METTL9,SMC4,ADCY7,USP34,POU2AF1,NRAS,NASP,MIOS,BIRC3,RBX1,RAB3IP,ZFAND5,BTBD1,ZFR,CYB5A,FNTA,ETS2,TWSG1,DCK,RWDD4,PSAP,ACADM,RNF14,CDK2,HDAC2,S100PBP |
| 5.993e-03 | -5.12 | GSE27786_LSK_VS_MONO_MAC_DN | MSigDB lists | GSE27786_LSK_VS_MONO_MAC_DN | 184 | 41 | 17377 | 2626 |
PRKAB1,CDS2,AGTRAP,HEXB,MON1B,ENSA,USP39,GYG1,ARF1,AP3S1,NDUFS4,RAP1A,SHC1,MED8,RINL,ATG3,MBD2,KIF14,PPP4R1,CITED2,FBXL19,ATP6V0D1,ABI1,CLPTM1,PLK1,RBM42,NEK7,RABIF,EIF2AK1,PLEC,HERPUD2,CCNF,SH3GLB1,HAUS8,WAS,MTHFD2,KBTBD7,TBPL1,BEND6,PDLIM5,GEMIN7 |
| 5.993e-03 | -5.12 | GSE15324_NAIVE_VS_ACTIVATED_ELF4_KO_CD8_TCELL_DN | MSigDB lists | GSE15324_NAIVE_VS_ACTIVATED_ELF4_KO_CD8_TCELL_DN | 184 | 41 | 17377 | 2626 |
SEPHS2,UBL3,SNX27,NAT9,SARNP,GPR89A,UCK2,GYG1,PPP1R16B,LCLAT1,REEP5,QSOX2,PAIP1,MAD2L2,FANCL,SNX18,MRPL40,NAA35,CSNK1G3,ELOF1,KLF10,ANKRD33B,TEX10,MTMR6,USP10,PRMT2,KRTCAP2,PRKRA,BORA,DOT1L,STOML2,SYNCRIP,SURF4,UEVLD,CHCHD1,EIF2D,EXOC4,PREPL,NDE1,GPR89B,CCDC137 |
| 5.993e-03 | -5.12 | GSE40685_NAIVE_CD4_TCELL_VS_FOXP3_KO_TREG_PRECURSOR_UP | MSigDB lists | GSE40685_NAIVE_CD4_TCELL_VS_FOXP3_KO_TREG_PRECURSOR_UP | 184 | 41 | 17377 | 2626 |
COX15,PRKAB1,NQO1,ANXA6,DCAF15,DYNLL1,NUP54,B4GALT1,SIKE1,BCL2L1,SLC35B1,OAT,SPAG5,FKBP1A,GOLM1,PRKD3,NUS1,NOL11,UBA5,MECR,FAM89B,MDFIC,TARDBP,CREB1,TMEM14C,ARL5A,TMBIM1,TSHZ1,PPP3CA,EXOSC9,FOXRED1,SNRPA,MYO1F,MASTL,SLCO4A1,AHNAK,STT3A,H2AFX,HMGB2,ANP32E,RBPJ |
| 5.993e-03 | -5.12 | GSE42088_UNINF_VS_LEISHMANIA_INF_DC_2H_UP | MSigDB lists | GSE42088_UNINF_VS_LEISHMANIA_INF_DC_2H_UP | 184 | 41 | 17377 | 2626 |
WSB2,KIF3B,TXN,NUP188,AGRN,NF1,TRIP10,SEC61G,FAM129A,TBC1D13,PLXNA1,GLRX3,DNAJB9,CFLAR,ZNF804A,PSMD1,GART,PSMA6,EXOSC7,ITGB8,AHSA1,ANXA5,TTC4,LRRC59,ACSL5,METTL1,RHOBTB3,LYRM1,ATP2C1,ATXN1,PRPF3,PRDX1,MAP3K4,KEAP1,SEC61A1,ST3GAL2,MAP3K5,PPP6R2,RPS6KC1,NRBP1,BYSL |
| 5.994e-03 | -5.12 | GSE4984_UNTREATED_VS_LPS_TREATED_DC_DN | MSigDB lists | GSE4984_UNTREATED_VS_LPS_TREATED_DC_DN | 157 | 36 | 17377 | 2626 |
ZCCHC9,KDM4A,UQCR10,B4GALT5,MANBA,PDAP1,DCTN2,PMVK,IFT27,TUBGCP2,SLC31A1,RPN1,KLHL5,TCEA1,PDIA6,TMEM14C,DNMT1,SNX25,TXNL1,MTA2,HTATIP2,NUP155,GLOD4,STOML2,GNAS,BOLA3,PON2,IDE,TXNDC16,CDC27,MEGF9,MAP3K5,WDR62,NGLY1,CDKN2A,ANAPC4 |
| 5.994e-03 | -5.12 | GSE4984_GALECTIN1_VS_LPS_STIM_DC_DN | MSigDB lists | GSE4984_GALECTIN1_VS_LPS_STIM_DC_DN | 157 | 36 | 17377 | 2626 |
CYTIP,GADD45G,NANS,GGA2,SLC20A1,GTF2F1,LYAR,PSMD2,RRN3,PRDM4,NAA50,RPN2,NFU1,PTGES3,TALDO1,FBL,PPA1,KCNAB2,FDFT1,PPAN,TXNL1,PLK3,TDP1,ADAM17,AKT2,GORASP2,GAR1,TMEM201,AKAP1,SDHB,HSPA4,TULP3,TIMM17A,DMWD,PDXK,RTN3 |
| 5.994e-03 | -5.12 | GSE40274_CTRL_VS_SATB1_TRANSDUCED_ACTIVATED_CD4_TCELL_UP | MSigDB lists | GSE40274_CTRL_VS_SATB1_TRANSDUCED_ACTIVATED_CD4_TCELL_UP | 157 | 36 | 17377 | 2626 |
CIB1,AP3M2,ASAH1,GMCL1,MXD4,DOCK11,MAPK14,ZADH2,SLC25A43,PIP4K2A,FERMT3,CDK5,STARD9,SP100,TBC1D14,CDC25B,CORO1A,LYPLA2,S100A6,KDELR1,ENPP4,SNX2,PPP1R21,ARSK,PSMB9,RHBDF2,MID1IP1,ITPRIPL1,RPL32,RBL1,DBI,MYO18A,RNASEL,PPP6R2,NAA60,HIGD2A |
| 6.001e-03 | -5.12 | NDUFS2 (NADH:ubiquinone oxidoreductase core subunit S2) | protein interactions | 4720 | 65 | 19 | 17029 | 2761 |
NDUFV2,NDUFS1,MKLN1,TIMMDC1,AGO2,CUL3,NDUFA4,ADRB2,OGDH,SDHA,APP,NDUFS7,CENPU,NDUFS4,NDUFV1,NDUFA11,NDUFS8,DMWD,NDUFS5 |
| 6.001e-03 | -5.12 | HIST2H4A (histone cluster 2 H4 family member a) | protein interactions | 8370 | 65 | 19 | 17029 | 2761 |
BRD4,NASP,KAT2A,CXXC1,CUL3,MCM2,UBE2I,ASF1B,CAND1,ATAD2,BRD2,UCHL5,E2F4,H2AFX,E2F1,BRD7,NAP1L4,RBBP4,SAP30 |
| 6.001e-03 | -5.12 | ETS1 (ETS proto-oncogene 1, transcription factor) | protein interactions | 2113 | 65 | 19 | 17029 | 2761 |
SRSF11,HTATIP2,BRCA1,PLEC,PKM,UBE2I,ETS1,APP,MAPK3,APLP2,ETS2,SP100,PTEN,STAT6,NCOA1,CYBC1,ZMIZ1,MAPK1,ATF2 |
| 6.001e-03 | -5.12 | AHCYL2 (adenosylhomocysteinase like 2) | protein interactions | 23382 | 65 | 19 | 17029 | 2761 |
FOXK1,ABCF2,PIP4K2C,DHX8,PIP4K2A,WDR48,RBM23,KIF18B,CLK3,RPL17,ZNHIT6,CAB39,ANP32E,DUSP11,AHCYL1,ARRB2,PDCD2L,ZC3H3,EEF1D |
| 6.001e-03 | -5.12 | ACTR1A (ARP1 actin related protein 1 homolog A) | protein interactions | 10121 | 65 | 19 | 17029 | 2761 |
MAPRE1,CYLD,DCTN2,CUL3,POLR2D,MYH9,CUL1,CAPZA2,BICD2,PSMC4,IWS1,KPNA4,PSMD1,HUWE1,RRS1,SMURF1,CCAR1,CDC5L,DCTN1 |
| 6.006e-03 | -5.11 | KHDRBS1 (KH RNA binding domain containing, signal transduction associated 1) | protein interactions | 10657 | 172 | 41 | 17029 | 2761 |
EWSR1,COPA,MPHOSPH8,SUZ12,DHX9,GLRX3,LYN,CRKL,RPA2,VAV1,CRY2,OSTF1,RBM15,STAT3,CDC5L,SRPK2,YTHDC1,USO1,NCK1,CUL3,CIRBP,BRCA1,MATR3,DHX15,FADD,RPA1,DDX17,CAND1,SMAD2,SYNCRIP,CSK,HNRNPR,RBMX,MIA2,ATXN2L,ACTB,DDX5,SRSF3,CD81,MAPK1,POT1 |
| 6.014e-03 | -5.11 | TBCD (tubulin folding cofactor D) | protein interactions | 6904 | 56 | 17 | 17029 | 2761 |
POLR2I,NASP,SNX2,CUL3,KRAS,GORASP2,VPS25,APP,PPP2CA,SH3GLB2,STAT1,STAT3,TERF1,POT1,VPS29,ZNF146,TUBB |
| 6.014e-03 | -5.11 | PDCD10 (programmed cell death 10) | protein interactions | 11235 | 56 | 17 | 17029 | 2761 |
MOB4,UNK,STRIP1,HEXB,STRN4,HNRNPF,EZR,SIKE1,CLNS1A,PPP2CA,PCNA,PPME1,CTPS1,CNN2,TATDN1,HEXA,FGFR1OP2 |
| 6.014e-03 | -5.11 | TRMT2A (tRNA methyltransferase 2 homolog A) | protein interactions | 27037 | 56 | 17 | 17029 | 2761 |
EXOC3,TK1,FEZ2,PBK,GADD45G,ASAH1,THNSL1,ERBIN,APP,ANKRD28,PIN1,PRMT7,DMWD,PPP6R2,PPP6R3,PPP6R1,PPP2R2D |
| 6.014e-03 | -5.11 | ZBTB8A (zinc finger and BTB domain containing 8A) | protein interactions | 653121 | 56 | 17 | 17029 | 2761 |
TRIM41,ZCCHC10,MCM10,WDYHV1,KAT7,PRPF3,UBE2I,RAD23A,KIF5B,MFAP1,PIAS2,AP1M1,AEN,PSMC1,BYSL,DVL2,ZBTB24 |
| 6.014e-03 | -5.11 | WDR4 (WD repeat domain 4) | protein interactions | 10785 | 56 | 17 | 17029 | 2761 |
METTL1,PCNA,TP53RK,HSPBP1,SAR1A,PPME1,ERO1A,OGT,ADSL,DDX5,DNAJB1,UBQLN2,ERC1,TERF1,NPLOC4,CARM1,TERF2 |
| 6.014e-03 | -5.11 | AP1G1 (adaptor related protein complex 1 subunit gamma 1) | protein interactions | 164 | 56 | 17 | 17029 | 2761 |
UNK,PRKAB1,CORO7,TRIP10,GGA1,ARF1,AP1B1,SYNRG,NECAP2,OSBPL11,ZNF746,AP1M1,AP2B1,GTSE1,AP1S1,PPP6R2,AP2S1 |
| 6.014e-03 | -5.11 | GDF9 (growth differentiation factor 9) | protein interactions | 2661 | 56 | 17 | 17029 | 2761 |
MOB4,ORAI2,TK1,GADD45G,STRN4,ILF3,ADPGK,PMF1,PRKRA,GNB2,PABPC4,CDKN2C,DNM2,NDUFB9,KIF22,SNRPG,PCYT2 |
| 6.014e-03 | -5.11 | DNAJC10 (DnaJ heat shock protein family (Hsp40) member C10) | protein interactions | 54431 | 56 | 17 | 17029 | 2761 |
TXNL1,TRAPPC13,TCF3,CUL3,CUL1,BRCA1,MCM2,CAND1,MTMR3,PTPN2,HSPA4,CDC42,LTBP4,MTMR4,FUS,IFI16,N4BP2L2 |
| 6.019e-03 | -5.11 | TNFAIP3 (TNF alpha induced protein 3) | protein interactions | 7128 | 93 | 25 | 17029 | 2761 |
OTUD5,TRIM8,ANKRD13D,NDUFS1,TNFAIP3,BIRC3,ZFAND5,BECN1,KIF11,GIT2,BIRC2,FADD,FBXO3,CCDC50,AXIN1,TICAM1,YWHAZ,MAP3K5,PPP6R3,RNF14,YWHAH,RNF5,ALDH9A1,RNF114,RLIM |
| 6.029e-03 | -5.11 | GCTNWTTGK_UNKNOWN | MSigDB lists | GCTNWTTGK_UNKNOWN | 284 | 59 | 17377 | 2626 |
CYLD,GGNBP2,TSC22D3,CDCA3,STARD7,KLF13,KIF23,SLC4A2,SND1,IP6K2,SLC20A1,CNOT3,PAIP2,USP5,CDK5,ATP2A2,ITGB8,UTP18,RAB35,IL6ST,SSBP3,FIZ1,TNPO3,OSTF1,OSTC,PRADC1,CITED2,ST8SIA2,ANKHD1,CCAR1,TACC3,TMEM160,PTPRK,SPTAN1,SP3,ZNF524,PPP1R9B,FOPNL,AMD1,ZBED5,WDR81,PLEC,SOX4,H2AFV,EIF4G2,RAB5B,USP21,NCDN,DPYSL3,SMAD2,SYNCRIP,LUC7L3,NAGLU,SEL1L,RNF38,ACTB,DDX5,TFDP2,ESPL1 |
| 6.029e-03 | -5.11 | TGCACTG,MIR-148A,MIR-152,MIR-148B | MSigDB lists | TGCACTG,MIR-148A,MIR-152,MIR-148B | 284 | 59 | 17377 | 2626 |
RORB,RMND5A,POU3F2,SNX27,TMED7,MAX,PPP1R12A,B4GALT5,PRKAA1,KIAA0232,SLC2A1,C5orf30,KLHL18,ARGLU1,AGFG1,USP48,SLC25A44,SNN,SSR1,C1GALT1,ATP2A2,RAB35,ZCCHC2,ARL6IP1,TNPO3,MDFIC,MARCH2,FBXL19,DNMT1,PPP6R1,MOSPD1,RLIM,SRSF11,MLEC,PBXIP1,BAZ2A,ERLIN1,BTAF1,MIER1,GMFB,E2F3,ATXN1,ARHGEF12,MTMR12,AP4E1,PATL1,PICALM,AKAP1,CAND1,OSBPL11,PLAA,ELMO1,USP32,RNF38,CNOT6,NCOA1,BTBD10,ABCA1,B4GALT2 |
| 6.041e-03 | -5.11 | COURTOIS_SENESCENCE_TRIGGERS | MSigDB lists | COURTOIS_SENESCENCE_TRIGGERS | 6 | 4 | 17377 | 2626 |
PTEN,NF1,E2F1,E2F3 |
| 6.043e-03 | -5.11 | trivalent inorganic cation transport | biological process | GO:0072512 | 41 | 13 | 17256 | 2622 |
ATP6V0B,ATP6V1D,RAB11B,DNM2,ATP6V0A2,ATP6V0A1,ATP6V0C,ATP6V1C1,ATP6V1B2,ATP6V0D1,ATP6V0E1,TFRC,ATP6V1G1 |
| 6.043e-03 | -5.11 | ferric iron transport | biological process | GO:0015682 | 41 | 13 | 17256 | 2622 |
ATP6V0B,ATP6V1D,RAB11B,DNM2,ATP6V0A2,ATP6V0A1,ATP6V0C,ATP6V1C1,ATP6V1B2,ATP6V0D1,ATP6V0E1,TFRC,ATP6V1G1 |
| 6.045e-03 | -5.11 | GSE360_DC_VS_MAC_M_TUBERCULOSIS_DN | MSigDB lists | GSE360_DC_VS_MAC_M_TUBERCULOSIS_DN | 195 | 43 | 17377 | 2626 |
NACA,GTF3A,FOXO3,REPS1,KTN1,LMNA,CNOT3,PHC2,CALM2,SNUPN,ADD3,PTEN,UTP18,ARF5,RAB4A,FBL,CTDSP2,IMPA2,ALDH9A1,USP34,CDC5L,SAP30,HMGN1,POLR2I,MIOS,SEPT9,GALC,BTAF1,KIAA0930,HEBP2,FRAT2,STOML2,EPRS,SERTAD2,HSPB11,RPS27A,TFE3,UBXN2B,HMGB2,RUVBL2,LTA4H,USF2,PTOV1 |
| 6.045e-03 | -5.11 | GSE5589_LPS_VS_LPS_AND_IL6_STIM_IL6_KO_MACROPHAGE_45MIN_UP | MSigDB lists | GSE5589_LPS_VS_LPS_AND_IL6_STIM_IL6_KO_MACROPHAGE_45MIN_UP | 195 | 43 | 17377 | 2626 |
CDS2,PKP4,TRIP10,DHPS,SESTD1,MDH2,SRGN,HEXB,ARID5A,MCCC1,ENSA,FLOT1,CDC42SE2,RAB6A,S1PR2,ETS1,PRNP,PRKD3,HOMER1,TIMM23,AHSA1,IL6ST,TARDBP,TMEM8A,ZDHHC18,ATP13A1,LONRF3,TMEM126B,SEPT8,ARHGEF12,TANC1,IRF5,RAB2B,RHOB,AHNAK,RAB24,ADAM9,CTSA,ST3GAL2,DMWD,PSAP,CD81,ABCA1 |
| 6.045e-03 | -5.11 | GSE39152_CD103_NEG_VS_POS_MEMORY_CD8_TCELL_UP | MSigDB lists | GSE39152_CD103_NEG_VS_POS_MEMORY_CD8_TCELL_UP | 195 | 43 | 17377 | 2626 |
AGRN,NF1,CDT1,ANKH,RRAGC,MAN2B1,RUFY1,PIP4K2A,KTN1,RBM17,CAPN2,IRF4,PRKD3,APLP2,ZKSCAN1,NVL,ADCY9,BRI3,TTC4,RBM15,LPCAT1,ALDH9A1,CPNE1,FAM118B,BTG2,DENND4C,VHL,PPP1R21,LRRC8A,ADRB2,ESYT1,SLC50A1,CYB5A,HSPA1B,PSMC4,PON2,DAP3,RPL32,RPS14,RUFY3,TRAF5,HEXA,CBX4 |
| 6.055e-03 | -5.11 | POLR2E (RNA polymerase II subunit E) | protein interactions | 5434 | 127 | 32 | 17029 | 2761 |
LZTR1,POLR2K,CSNK2A1,POLR3K,WWP2,SPINDOC,RPA2,MED10,CD3EAP,POLR1B,ZNRD1,RPRD1B,RPAP3,POLR2I,POLR2L,POLR2G,HELB,POLR2D,CUL3,ELOA,BRCA1,PSMB9,TRIM28,POLR2A,XRCC5,RPA1,BRMS1,POLR2J,PML,RUVBL2,USP11,ARRB2 |
| 6.085e-03 | -5.10 | GO_LYTIC_VACUOLE_MEMBRANE | MSigDB lists | GO_LYTIC_VACUOLE_MEMBRANE | 256 | 54 | 17377 | 2626 |
RAB14,DNAJC5,ANXA6,CCZ1,ABCC10,LAMTOR3,FLOT1,AP1B1,ATP6V1B2,PSEN1,TMEM165,GNB2,SPPL2A,NAPG,ZNRF2,AP1M1,CLCN6,ATP6V0A2,AP2B1,MARCH2,TMEM8A,TPCN1,TMEM9,ATP6V0D1,TMBIM1,DRAM2,ATP6V1G1,WDR41,ACP2,MIOS,GOPC,RAB7A,GBA,SLC17A5,SPPL2B,NEU1,RHEB,PI4K2A,SCARB2,ATP6V1D,AHNAK,WDR11,NSF,CCZ1B,AP1S1,CTSA,ATP6V0C,SCARB1,PSAP,ATP6V1C1,CLN3,AP2S1,SNX14,STARD3NL |
| 6.087e-03 | -5.10 | chromatin DNA binding | molecular function | GO:0031490 | 108 | 27 | 17224 | 2647 |
KDM3B,HMGN1,H2AFZ,HMGN5,HMGN4,MTA2,SUZ12,DHX9,WBP2,SMARCA4,CTCF,HMGN3,KDM3A,MBD3,FOXO3,HMGN2,LEMD2,ANKLE1,MBD2,H2AFY,ACTB,RUVBL2,H3F3A,RBBP4,SMARCE1,STAT3,HDAC2 |
| 6.109e-03 | -5.10 | protein K11-linked ubiquitination | biological process | GO:0070979 | 28 | 10 | 17256 | 2622 |
UBE2D3,CDC16,UBE2E2,CDC27,ANAPC7,ANAPC2,CDC23,RNF26,UBE2C,ANAPC4 |
| 6.109e-03 | -5.10 | production of miRNAs involved in gene silencing by miRNA | biological process | GO:0035196 | 28 | 10 | 17256 | 2622 |
HNRNPA2B1,SMAD2,DGCR8,ZC3H7B,AGO2,PRKRA,SMAD1,SRRT,METTL3,TUT4 |
| 6.131e-03 | -5.09 | Transferrin endocytosis and recycling | REACTOME pathways | R-HSA-917977 | 30 | 11 | 10287 | 1696 |
ATP6V0B,ATP6V1D,ATP6V0A1,ATP6V0A2,ATP6V0C,ATP6V1B2,ATP6V1C1,ATP6V0E1,ATP6V0D1,TFRC,ATP6V1G1 |
| 6.131e-03 | -5.09 | FCERI mediated Ca+2 mobilization | REACTOME pathways | R-HSA-2871809 | 30 | 11 | 10287 | 1696 |
CALM2,VAV1,PPP3CA,NFATC3,SHC1,VAV2,PPP3R1,NFATC2,PPP3CB,AHCYL1,LYN |
| 6.131e-03 | -5.09 | Recognition of DNA damage by PCNA-containing replication complex | REACTOME pathways | R-HSA-110314 | 30 | 11 | 10287 | 1696 |
DTL,RPA2,PCNA,RFC3,POLE,RAD18,RBX1,RPS27A,RFC2,DDB1,RPA1 |
| 6.139e-03 | -5.09 | GO_NEGATIVE_REGULATION_OF_RNA_SPLICING | MSigDB lists | GO_NEGATIVE_REGULATION_OF_RNA_SPLICING | 24 | 9 | 17377 | 2626 |
HNRNPA2B1,RBM42,AKT2,RBMX,SRSF6,SRSF4,RNPS1,RPS26,SRSF10 |
| 6.139e-03 | -5.09 | PID_S1P_S1P2_PATHWAY | MSigDB lists | PID_S1P_S1P2_PATHWAY | 24 | 9 | 17377 | 2626 |
GNA12,RHOA,RAC1,ELK1,S1PR2,MAPK1,GNAI2,MAPK14,MAPK3 |
| 6.139e-03 | -5.09 | GO_ESCRT_COMPLEX | MSigDB lists | GO_ESCRT_COMPLEX | 24 | 9 | 17377 | 2626 |
CHMP2A,HGS,CHMP4A,CHMP4B,VPS4A,CHMP2B,CHMP7,VPS25,STAM |
| 6.139e-03 | -5.09 | BIOCARTA_EIF4_PATHWAY | MSigDB lists | BIOCARTA_EIF4_PATHWAY | 24 | 9 | 17377 | 2626 |
PDPK1,PDK2,MKNK1,PTEN,EIF4G2,MAPK14,MAPK1,PABPC1,MAPK3 |
| 6.139e-03 | -5.09 | REACTOME_NUCLEAR_EVENTS_KINASE_AND_TRANSCRIPTION_FACTOR_ACTIVATION | MSigDB lists | REACTOME_NUCLEAR_EVENTS_KINASE_AND_TRANSCRIPTION_FACTOR_ACTIVATION | 24 | 9 | 17377 | 2626 |
PPP2CA,MEF2A,CREB1,ELK1,MAPK14,DUSP3,MAPK1,RPS6KA1,MAPK3 |
| 6.139e-03 | -5.09 | XU_CREBBP_TARGETS_UP | MSigDB lists | XU_CREBBP_TARGETS_UP | 24 | 9 | 17377 | 2626 |
PPAN,ALG3,TSTA3,NVL,ADSL,MCM2,TMEM159,KTN1,S100A6 |
| 6.139e-03 | -5.09 | REACTOME_CYTOSOLIC_TRNA_AMINOACYLATION | MSigDB lists | REACTOME_CYTOSOLIC_TRNA_AMINOACYLATION | 24 | 9 | 17377 | 2626 |
FARSA,KARS,EPRS,LARS,IARS,HARS,QARS,PPA1,TARS |
| 6.139e-03 | -5.09 | REACTOME_TGF_BETA_RECEPTOR_SIGNALING_ACTIVATES_SMADS | MSigDB lists | REACTOME_TGF_BETA_RECEPTOR_SIGNALING_ACTIVATES_SMADS | 24 | 9 | 17377 | 2626 |
TGFB1,FKBP1A,SMAD2,MTMR4,RPS27A,UCHL5,SMURF1,STRAP,SMAD4 |
| 6.139e-03 | -5.09 | BIOCARTA_G2_PATHWAY | MSigDB lists | BIOCARTA_G2_PATHWAY | 24 | 9 | 17377 | 2626 |
PLK1,MDM2,PRKDC,RPS6KA1,CDC25B,CHEK2,BRCA1,CCNB1,YWHAH |
| 6.149e-03 | -5.09 | GSE19888_ADENOSINE_A3R_INH_PRETREAT_AND_ACT_BY_A3R_VS_A3R_INH_AND_TCELL_MEMBRANES_ACT_MAST_CELL_UP | MSigDB lists | GSE19888_ADENOSINE_A3R_INH_PRETREAT_AND_ACT_BY_A3R_VS_A3R_INH_AND_TCELL_MEMBRANES_ACT_MAST_CELL_UP | 168 | 38 | 17377 | 2626 |
UBL3,ZBTB10,PNISR,SRGN,MED13L,RGS2,DUSP22,FOXO3,JMY,PAIP2,CFLAR,MAT2B,GNS,APLP2,RAB21,HOMER1,NAA50,RNF19A,PIK3IP1,CTDSP2,SOCS5,TNFAIP3,RB1CC1,PFKFB3,PNPLA8,SOX4,HERPUD2,RPL27A,PDE3B,PICALM,SMAP2,PI4K2A,VEZF1,KPNA1,ARAP1,DDX5,N4BP2L2,ZSWIM6 |
| 6.157e-03 | -5.09 | GARGALOVIC_RESPONSE_TO_OXIDIZED_PHOSPHOLIPIDS_BLUE_UP | MSigDB lists | GARGALOVIC_RESPONSE_TO_OXIDIZED_PHOSPHOLIPIDS_BLUE_UP | 115 | 28 | 17377 | 2626 |
HSPH1,IFRD1,C16orf72,KLHL21,TSC22D3,CBLL1,NFATC2,JMJD6,DNAJA1,ZNRF3,DNAJB1,PNPLA8,MXD1,DNAJB9,SRXN1,CREM,ZNF473,AHSA1,MAFK,NFIL3,VCPIP1,EIF5,SMURF1,FGFR1OP2,N4BP2L2,RHEBL1,RYBP,CWC25 |
| 6.157e-03 | -5.09 | chaperone-mediated protein folding | biological process | GO:0061077 | 79 | 21 | 17256 | 2622 |
PPIB,HSPH1,CCT2,ST13,DNAJB2,ERO1A,DNAJC24,ZFYVE21,CSNK2A1,DNAJB1,FKBP2,FKBP3,CCT8,BBS12,HSPA1B,FKBP1A,HSPA4,FKBP5,PTGES3,CLU,PIKFYVE |
| 6.157e-03 | -5.09 | positive regulation of response to DNA damage stimulus | biological process | GO:2001022 | 79 | 21 | 17256 | 2622 |
NSMCE4A,FOXM1,EYA1,BABAM1,DHX9,MRNIP,BCLAF1,BRCA1,TRIM28,ANKLE1,BABAM2,PCNA,TIGAR,CEBPG,H2AFX,TIMELESS,DDX5,SLF1,EYA2,SLF2,SPIDR |
| 6.157e-03 | -5.09 | regulation of transcription from RNA polymerase II promoter in response to hypoxia | biological process | GO:0061418 | 79 | 21 | 17256 | 2622 |
UBE2D3,RBX1,PSMA8,VHL,PSMB7,PSMA1,SIRT2,PSMB9,PSMD9,PSMB3,PSMC4,PSMD2,PSMD1,PSMA6,RPS27A,PSMD8,PSMD3,RBPJ,CITED2,PSMC1,EGLN1 |
| 6.165e-03 | -5.09 | ATXN7 (ataxin 7) | protein interactions | 6314 | 79 | 22 | 17029 | 2761 |
AGRN,KAT2A,SUMO2,TAF6L,USP22,UBQLN2,UBE2I,RAD23A,PSMD2,GOLGA2,LTBP4,SIAH1,MEGF8,PPP1R12C,NOC2L,NUP62,TAF5L,TP53BP2,TAF12,LRSAM1,PSMC1,SGF29 |
| 6.165e-03 | -5.09 | SCF complex assembly | biological process | GO:0010265 | 6 | 4 | 17256 | 2622 |
CUL1,FBXL7,RBX1,CAND1 |
| 6.165e-03 | -5.09 | mitotic centrosome separation | biological process | GO:0007100 | 6 | 4 | 17256 | 2622 |
NUP62,KIF3B,NDE1,KIF11 |
| 6.165e-03 | -5.09 | regulation of DNA-dependent DNA replication initiation | biological process | GO:0030174 | 6 | 4 | 17256 | 2622 |
CDK2,CDT1,WDR18,WRNIP1 |
| 6.165e-03 | -5.09 | negative regulation of protein K63-linked ubiquitination | biological process | GO:1900045 | 6 | 4 | 17256 | 2622 |
TRIP12,PLAA,GPS2,PARP10 |
| 6.165e-03 | -5.09 | positive regulation of helicase activity | biological process | GO:0051096 | 6 | 4 | 17256 | 2622 |
CHTOP,POT1,MSH6,MSH2 |
| 6.165e-03 | -5.09 | protein localization to endoplasmic reticulum exit site | biological process | GO:0070973 | 6 | 4 | 17256 | 2622 |
BCAP29,SEC16A,BCAP31,MIA2 |
| 6.168e-03 | -5.09 | JAK-STAT signaling | KEGG pathways | hsa_M00684 | 19 | 8 | 7161 | 1149 |
JAK1,STAT6,STAT1,SOCS4,SOCS6,STAT3,SOCS5,SOCS7 |
| 6.168e-03 | -5.09 | JAK-STAT signaling | KEGG pathways | M00684 | 19 | 8 | 7161 | 1149 |
JAK1,STAT6,STAT1,SOCS4,SOCS6,STAT3,SOCS5,SOCS7 |
| 6.170e-03 | -5.09 | GO_REGULATION_OF_TRANSCRIPTION_ELONGATION_FROM_RNA_POLYMERASE_II_PROMOTER | MSigDB lists | GO_REGULATION_OF_TRANSCRIPTION_ELONGATION_FROM_RNA_POLYMERASE_II_PROMOTER | 20 | 8 | 17377 | 2626 |
PAF1,BRD4,ZMYND11,AXIN1,CTR9,RTF1,CDC73,GTF2F1 |
| 6.170e-03 | -5.09 | GO_ENDOPLASMIC_RETICULUM_CALCIUM_ION_HOMEOSTASIS | MSigDB lists | GO_ENDOPLASMIC_RETICULUM_CALCIUM_ION_HOMEOSTASIS | 20 | 8 | 17377 | 2626 |
BAK1,ATP2A2,PML,KCTD17,BCL2,PSEN1,BCAP31,APP |
| 6.170e-03 | -5.09 | WALLACE_PROSTATE_CANCER_UP | MSigDB lists | WALLACE_PROSTATE_CANCER_UP | 20 | 8 | 17377 | 2626 |
PPP3CA,UAP1,TSTA3,DAP,BDH1,AHCY,SOX4,ODC1 |
| 6.170e-03 | -5.09 | GO_MICROTUBULE_END | MSigDB lists | GO_MICROTUBULE_END | 20 | 8 | 17377 | 2626 |
DST,KIF2C,MAPRE2,MAPRE1,KIF18B,ASPM,MYO5A,SPAG5 |
| 6.170e-03 | -5.09 | GO_NUCLEAR_LOCALIZATION_SEQUENCE_BINDING | MSigDB lists | GO_NUCLEAR_LOCALIZATION_SEQUENCE_BINDING | 20 | 8 | 17377 | 2626 |
KPNA4,KPNA1,TNPO3,TNPO2,BRAP,KPNA2,NUP153,IPO4 |
| 6.170e-03 | -5.09 | GO_ESTABLISHMENT_OF_PROTEIN_LOCALIZATION_TO_GOLGI | MSigDB lists | GO_ESTABLISHMENT_OF_PROTEIN_LOCALIZATION_TO_GOLGI | 20 | 8 | 17377 | 2626 |
PACS1,GCC2,GOLGA4,RAB6A,NRAS,SYS1,GCC1,OPTN |
| 6.170e-03 | -5.09 | PID_WNT_CANONICAL_PATHWAY | MSigDB lists | PID_WNT_CANONICAL_PATHWAY | 20 | 8 | 17377 | 2626 |
DVL1,PPP2R5A,CSNK1G1,AXIN1,DVL2,PI4K2A,NKD2,CUL3 |
| 6.170e-03 | -5.09 | GO_RESPONSE_TO_LEAD_ION | MSigDB lists | GO_RESPONSE_TO_LEAD_ION | 20 | 8 | 17377 | 2626 |
CAT,ANXA5,DNMT3A,PPP5C,DNMT1,APP,MECP2,CPOX |
| 6.170e-03 | -5.09 | REACTOME_NEF_MEDIATES_DOWN_MODULATION_OF_CELL_SURFACE_RECEPTORS_BY_RECRUITING_THEM_TO_CLATHRIN_ADAPTERS | MSigDB lists | REACTOME_NEF_MEDIATES_DOWN_MODULATION_OF_CELL_SURFACE_RECEPTORS_BY_RECRUITING_THEM_TO_CLATHRIN_ADAPTERS | 20 | 8 | 17377 | 2626 |
AP2B1,AP1S1,PACS1,ARF1,AP1B1,AP2S1,HLA-A,AP1M1 |
| 6.170e-03 | -5.09 | REACTOME_SHC1_EVENTS_IN_ERBB4_SIGNALING | MSigDB lists | REACTOME_SHC1_EVENTS_IN_ERBB4_SIGNALING | 20 | 8 | 17377 | 2626 |
KRAS,NRAS,SHC1,MAPK1,HRAS,RAF1,MAP2K2,MAPK3 |
| 6.170e-03 | -5.09 | GO_ANAPHASE_PROMOTING_COMPLEX | MSigDB lists | GO_ANAPHASE_PROMOTING_COMPLEX | 20 | 8 | 17377 | 2626 |
CDC16,CDC27,ANAPC7,ANAPC2,CDC23,UBE2C,ANAPC4,MAD2L2 |
| 6.170e-03 | -5.09 | GO_PROTEIN_DEGLYCOSYLATION | MSigDB lists | GO_PROTEIN_DEGLYCOSYLATION | 20 | 8 | 17377 | 2626 |
MAN2A2,MAN1B1,SEL1L,SYVN1,MAN2B1,EDEM2,PARK7,MAN1A1 |
| 6.171e-03 | -5.09 | N-Glycan antennae elongation | REACTOME pathways | R-HSA-975577 | 15 | 7 | 10287 | 1696 |
B4GALT1,B4GALT3,B4GALT4,ST8SIA2,B4GALT5,MGAT5,B4GALT2 |
| 6.189e-03 | -5.08 | H2AFV (H2A histone family member V) | protein interactions | 94239 | 43 | 14 | 17029 | 2761 |
COX15,C9orf78,PCNA,EWSR1,TM9SF4,MCM5,NUP107,CUL3,AHCY,MCM2,VDAC1,HEXA,APP,CAND1 |
| 6.189e-03 | -5.08 | RFPL4B (ret finger protein like 4B) | protein interactions | 442247 | 43 | 14 | 17029 | 2761 |
JMJD4,KDM3B,ZBTB10,LONRF3,POLR2J,ZNF302,MIOS,KRBA1,ZKSCAN1,TAB2,DDA1,PML,POLR3K,EGLN1 |
| 6.189e-03 | -5.08 | RBMS1 (RNA binding motif single stranded interacting protein 1) | protein interactions | 5937 | 43 | 14 | 17029 | 2761 |
SUGP1,PPIF,PPIB,SARNP,RRBP1,NABP2,RPL38,PQBP1,DNM2,NDUFA7,FAM136A,RRS1,UBE2I,SMAP2 |
| 6.189e-03 | -5.08 | MAT2A (methionine adenosyltransferase 2A) | protein interactions | 4144 | 43 | 14 | 17029 | 2761 |
MAT2B,SDHB,HGS,CYLD,CUL3,BCL2,FUS,MCM2,UBE2I,SMURF1,SDHA,NMD3,MAT2A,TUBB |
| 6.189e-03 | -5.08 | DDX28 (DEAD-box helicase 28) | protein interactions | 55794 | 43 | 14 | 17029 | 2761 |
MRPL2,MRPL9,ATP6V1D,MRPL42,MPHOSPH8,RAB11B,CUL3,LAMTOR3,MRPL11,MATR3,MRPL32,MRPL57,IFI16,SSSCA1 |
| 6.189e-03 | -5.08 | MTMR4 (myotubularin related protein 4) | protein interactions | 9110 | 43 | 14 | 17029 | 2761 |
MTMR3,DNAJC10,RAB8A,RB1CC1,MTMR4,WDYHV1,CEP55,EXOC4,ENSA,YWHAZ,YWHAH,RAB11A,HIPK3,TMEM160 |
| 6.189e-03 | -5.08 | SOD2 (superoxide dismutase 2) | protein interactions | 6648 | 43 | 14 | 17029 | 2761 |
NOL12,CAT,UBR2,PRDX5,RAB4A,NABP2,TKT,H2AFX,MDH1,OAT,HDHD2,APP,USP36,GPX4 |
| 6.189e-03 | -5.08 | MRPL21 (mitochondrial ribosomal protein L21) | protein interactions | 219927 | 43 | 14 | 17029 | 2761 |
MRPL50,MRPL9,CYLD,MRPL42,MRPL39,GRSF1,IARS2,CUL3,TOP3A,DUSP11,MRPL40,ZC3H3,MRPL19,MRPL32 |
| 6.189e-03 | -5.08 | GO_NEGATIVE_REGULATION_OF_CELLULAR_PROTEIN_LOCALIZATION | MSigDB lists | GO_NEGATIVE_REGULATION_OF_CELLULAR_PROTEIN_LOCALIZATION | 136 | 32 | 17377 | 2626 |
HSPH1,CYLD,TXN,NF1,RAB23,BCL2L1,PARK7,CDK5,SP100,SRI,AXIN2,FAM89B,H2AFY,MDFIC,TMBIM1,TGFB1,GOPC,RANGAP1,SOX4,AKAP1,KEAP1,PPP2R5A,TONSL,CSK,OGT,ZNF268,PKD2,PARP10,TERF1,FAF1,NUMB,SVIP |
| 6.189e-03 | -5.08 | RODWELL_AGING_KIDNEY_NO_BLOOD_DN | MSigDB lists | RODWELL_AGING_KIDNEY_NO_BLOOD_DN | 136 | 32 | 17377 | 2626 |
NDUFS1,MUT,C5orf30,CSNK2A1,CYCS,OAT,PAIP1,C2orf68,SLC25A36,FBXO3,APLP2,GOT2,UCHL5,HADHB,AHCYL1,NAA35,FAM171A1,PCBP2,LDHB,RHOBTB3,SLC16A7,ZFAND5,MTR,CYB5A,GNAS,FBXO21,UAP1,PRDX3,LRPPRC,COX8A,DHTKD1,SLC22A23 |
| 6.192e-03 | -5.08 | GO_GTPASE_BINDING | MSigDB lists | GO_GTPASE_BINDING | 290 | 60 | 17377 | 2626 |
KIF3B,TBC1D12,ANKRD27,TSC2,RAF1,RAC1,CIB1,ARFIP2,TBC1D13,MYO9B,NCKAP1,XPO7,GGA2,DOCK11,GNB2,RAPGEF6,RTKN,RAB8A,RAP1A,IARS,TBC1D22A,WDR44,RABGAP1L,TBC1D14,TNPO2,ARHGEF2,YBX1,NUP153,SYTL3,DVL2,MICAL3,MYO5A,CYFIP1,RHOBTB3,NXT1,NET1,RAB7A,RANGAP1,ARHGDIB,NUTF2,BICD2,ERC1,DAPK3,OPTN,STOML2,EPRS,TMEM127,INF2,GOLGA4,PEX5,NSF,BIRC5,CORO1C,ODF2,EXOC4,ROCK1,DVL1,ABCA1,ALS2,IPO4 |
| 6.197e-03 | -5.08 | purine nucleoside triphosphate biosynthetic process | biological process | GO:0009145 | 84 | 22 | 17256 | 2622 |
TGFB1,GALK1,COX5B,LDHA,ATP6V0A1,OGDH,ATP5F1B,ADPGK,PKM,ATP5MF,ATP5PF,STOML2,ATP5MC3,IMPDH1,ATP6V0A2,DHTKD1,CYC1,ATP5F1A,GPI,NIPSNAP2,PGAM1,PFKP |
| 6.221e-03 | -5.08 | SANT | prosite domains | PS51293 | 26 | 9 | 12060 | 1670 |
RCOR1,DNAJC2,NCOR2,MIER2,TRERF1,RCOR3,MTA1,MTA2,MIER1 |
| 6.221e-03 | -5.08 | DEAD_ATP_HELICASE | prosite domains | PS00039 | 26 | 9 | 12060 | 1670 |
DDX47,DDX24,EIF4A3,DDX20,DDX31,DDX5,DDX42,DDX17,DDX23 |
| 6.221e-03 | -5.08 | BROMODOMAIN_1 | prosite domains | PS00633 | 26 | 9 | 12060 | 1670 |
BRD4,BRWD1,KAT2A,BRD2,BRPF3,BAZ2A,BAZ1B,SMARCA4,PBRM1 |
| 6.222e-03 | -5.08 | Signaling events mediated by PRL | Pathway Interaction DB | prlsignalingeventspathway | 23 | 10 | 2226 | 426 |
RHOA,CCNA2,RHOC,RAC1,ITGB1,PTP4A3,ROCK1,CDK2,MAPK1,MAPK3 |
| 6.224e-03 | -5.08 | GSE21033_3H_VS_12H_POLYIC_STIM_DC_UP | MSigDB lists | GSE21033_3H_VS_12H_POLYIC_STIM_DC_UP | 152 | 35 | 17377 | 2626 |
USP7,URB2,SCYL1,CERK,PTP4A3,MEF2A,BCL2L1,CNTROB,PPP1R16B,PAIP1,GTF2F1,ATP13A3,TAP2,MYBL1,FBXL19,LRRC59,RPRD1B,SENP1,UBE2QL1,RBM15B,STAU1,KAT7,NUP155,ICAM2,GSTCD,CYFIP2,EIF3A,PTPRF,SEC23IP,PTPN7,SLC16A1,PSAP,PPP5C,MAPK1,HDAC2 |
| 6.230e-03 | -5.08 | positive regulation of catalytic activity | biological process | GO:0043085 | 1413 | 248 | 17256 | 2622 |
CCNC,TXN,TSC2,AGRN,MAP3K7CL,NF1,PPP1R15B,DNAJC24,AGFG1,CCNL2,CCNB1,UBE2I,S1PR2,MAPK14,GIT2,RIC1,ELMOD2,PARK7,PRNP,CDK5,CALM2,ABL2,PCNA,ASAP2,RAP1A,RABGAP1L,PIK3R2,RAB4A,DNM2,RP2,TCEA1,CDC25B,EIF5,SENP1,MLST8,PLK1,COPS8,BAK1,LARS,APH1A,AKT2,ARHGAP45,GMFB,MRNIP,CDC6,ARHGDIB,TOPORS,UBE2V1,AURKB,DCUN1D5,PRKRA,RFC2,ARF4,MAP3K4,TBC1D17,MID1IP1,RPS27A,AXIN1,ITGB1,MIA2,CAB39,ADAM9,STK11,CLU,POT1,HSPH1,TBC1D12,CLSPN,PPP1R12A,MUT,GMFG,GORASP1,DNAJB2,CHTF18,RHOC,GADD45G,VAV2,PRKAA1,DHX9,CIB1,ACAP1,LAMTOR3,RACGAP1,CYCS,DNAJB1,RGS2,DOCK11,APH1B,PARN,PSEN1,RAPGEF6,APOPT1,CFLAR,DDRGK1,TFAP4,NUS1,TIGAR,SNX18,RINL,MSH2,DAPK1,BCL2,MDFIC,GNAI2,TERF2,PREB,MAPKAPK3,KRAS,MAP4K3,ADRB2,CYFIP2,MAP2K2,ARHGAP15,FAS,XRCC5,TSC1,FNTA,GOLGA2,CSK,ARAP1,CTSA,MAP3K5,MYO9A,ALS2,RHOG,ANKRD27,KARS,TRAF7,IFI27L1,TRIP10,DYNLL1,RAF1,TOR1AIP1,MAGED1,TPX2,TBC1D13,DAZAP2,PRKACA,LYN,BCAP31,APP,HNRNPA2B1,VAV1,CRKL,SHC1,SH3BP1,RALB,NVL,TBC1D22A,PIN1,KIF14,TBC1D14,ADCY9,PDCD2,CDKN1B,CHTOP,F2R,ABI1,GM2A,HTRA2,DVL2,DNAL4,ADCY7,CCT2,ARHGAP17,TIMP2,PSRC1,RFC3,TAOK1,MAP4K4,DNAJC9,TOR1AIP2,DNAJA1,RAB1A,AFDN,PPP2CA,DNAJC10,TAB2,CORO1C,GADD45B,RPLP1,SCARB1,CCDC125,PITRM1,MAPK1,XRCC4,LRP8,MIF,DNAJC2,GCLM,SMAP1,PKP4,RPS2,DEPDC1,DAP,ZFP91,DBF4,MYO9B,DCUN1D4,RGS1,GTF2F1,FBXO5,CCNK,FGFR3,PDCD10,PTEN,AHSA1,ARHGEF1,TANK,PTPN11,AXIN2,DCP1A,ATG13,PTGES3,MAP3K14,STAT3,MSH6,PDPK1,TGFB1,TELO2,ADAM17,RHOA,HMGN1,DENND1B,NEK7,NET1,JTB,PRKAR1B,ARHGEF12,RANGAP1,MARK2,PICALM,FADD,SMAP2,MAPK3,PDCD6,NEK1,PLAA,OSBPL8,PML,HMGB2,PKD2,PSAP,CD81,ARHGAP23,UBE2C,HRAS,IFI16 |
| 6.252e-03 | -5.07 | GO_TRANSFERASE_ACTIVITY_TRANSFERRING_ACYL_GROUPS | MSigDB lists | GO_TRANSFERASE_ACTIVITY_TRANSFERRING_ACYL_GROUPS | 234 | 50 | 17377 | 2626 |
NAT14,NAT9,GNPNAT1,ZDHHC8,AGPAT1,AGPAT3,TAF6L,CHAC2,SUPT7L,WDR5,LCLAT1,SAP130,CRAT,ZDHHC13,CS,HADHB,NAA50,TAF5L,SPTSSA,LPCAT1,ATF2,SMARCE1,NCOA2,ZDHHC18,ELOVL5,KAT2A,KAT7,ELP4,USP22,EDF1,TAZ,PDHX,ZDHHC3,NMT2,ABHD5,AGPAT2,CERS6,LPCAT4,ACLY,OGT,ZDHHC7,ACAT1,ATE1,MBOAT1,NCOA1,TAF12,NAA20,OSGEPL1,SAT2,NAA60 |
| 6.253e-03 | -5.07 | - | gene3d domains | 1.25.40.90 | 27 | 10 | 8148 | 1295 |
HGS,RPRD1A,CHERP,GGA1,U2SURP,EPN1,GGA2,STAM,RPRD1B,PICALM |
| 6.255e-03 | -5.07 | GSE26669_CTRL_VS_COSTIM_BLOCK_MLR_CD4_TCELL_DN | MSigDB lists | GSE26669_CTRL_VS_COSTIM_BLOCK_MLR_CD4_TCELL_DN | 179 | 40 | 17377 | 2626 |
SEPHS2,MBD1,TSC22D3,ALKBH5,CHIC2,IKBIP,GGA2,PITHD1,RNF103,MBD4,SEC11A,RB1,ADD3,ADCY9,DDX31,CABLES2,ACAD8,ATP6V0D1,N4BP2,SAP30,TSHZ1,ULK3,ZMYM5,TEX10,KIAA0930,MFNG,RFFL,RIT1,PRMT2,ICAM2,RHOT1,SCARB2,JAK1,FAM3C,PRPS2,TRIM32,NCOA1,RGL1,YY1,MAP3K5 |
| 6.298e-03 | -5.07 | HOSHIDA_LIVER_CANCER_SURVIVAL_DN | MSigDB lists | HOSHIDA_LIVER_CANCER_SURVIVAL_DN | 110 | 27 | 17377 | 2626 |
PTPN18,SUCLG1,FAM129A,CPOX,ATP2C1,TMEM97,DLGAP4,RRM1,NENF,RLF,RFC2,CCT8,PSMB3,CYB5A,ARF4,ANKRD46,ZER1,PTPN2,DST,DAD1,XPA,CTBS,DCAF11,PCYT2,CREB1,MSH6,ALDH9A1 |
| 6.303e-03 | -5.07 | regulation of protein localization to membrane | biological process | GO:1905475 | 162 | 37 | 17256 | 2622 |
RHOG,DYNLL1,ANK3,NKD2,CIB1,BCL2L1,RAB11A,PRNP,MIEF1,KIF5B,CDK5,CNPY4,AP2B1,BCL2,TP53BP2,TMBIM1,CHP1,TGFB1,PDPK1,AKT2,GOPC,ACSL3,EZR,PICALM,APPL1,PPP2R5A,CSK,TFDP1,PPP3R1,E2F1,ITGB1,YWHAZ,VPS4A,TFDP2,YWHAH,C2CD5,NUMB |
| 6.318e-03 | -5.06 | nuclear transcription factor complex | cellular component | GO:0044798 | 188 | 41 | 18223 | 2701 |
RORB,TCF12,MAX,HNRNPAB,TCF3,TAF6L,SNAPC4,GTF2F1,RB1,NFATC3,MED8,MED10,CD3EAP,TAF5L,TCEA1,CREB1,STAT3,GTF2H2,CARM1,POU2AF1,GTF3C6,ERCC1,KAT2A,LDB1,E2F3,NFATC2,EDF1,PRMT2,SOX4,TRIM28,TAF2,SMAD2,HIPK2,TFDP1,TBPL1,E2F1,TAF12,TFDP2,TAF6,E2F2,SMAD4 |
| 6.318e-03 | -5.06 | GSE360_CTRL_VS_M_TUBERCULOSIS_MAC_DN | MSigDB lists | GSE360_CTRL_VS_M_TUBERCULOSIS_MAC_DN | 190 | 42 | 17377 | 2626 |
TRIP10,LETMD1,BECN1,REPS1,PHC2,PTPN2,CDKN2C,DUS4L,GATC,ATP2A2,ATP13A3,CREB1,ZNF189,SOCS5,SAP30,COPS8,PLK1,CSNK1G2,IFRD1,STAU1,MKLN1,VDAC2,MEF2D,PPWD1,MCM2,PRKRA,PRPSAP1,PDHX,MAT2A,RHEB,OPTN,TAF2,HSPB11,PFDN4,CERS6,HPS5,TFE3,GADD45B,STAT1,ANP32E,TFDP2,HDAC2 |
| 6.318e-03 | -5.06 | GSE17580_UNINFECTED_VS_S_MANSONI_INF_TREG_UP | MSigDB lists | GSE17580_UNINFECTED_VS_S_MANSONI_INF_TREG_UP | 190 | 42 | 17377 | 2626 |
OTUD5,IER2,PRPF38B,ASH1L,PIGN,SMC6,ARFIP2,CTCF,ATG2B,CCNL2,CDK11B,RUFY1,GFM2,RABGAP1L,BCL2,RHBDD2,CDK12,SMC4,TERF2,NRAS,AACS,TAOK1,ITM2A,BICD2,ZFR,PPP2CA,TMEM184C,C1orf131,BRWD1,TXNDC16,PDLIM1,CCDC6,DGCR8,HNRNPH3,FASTK,STK38,ARNTL,SH3GLB2,FBXL3,PURA,RAD51D,CCDC137 |
| 6.318e-03 | -5.06 | GO_NEGATIVE_REGULATION_OF_APOPTOTIC_SIGNALING_PATHWAY | MSigDB lists | GO_NEGATIVE_REGULATION_OF_APOPTOTIC_SIGNALING_PATHWAY | 190 | 42 | 17377 | 2626 |
MIF,BCL2L12,HSPH1,GCLM,IVNS1ABP,EYA1,RAF1,BCL2L1,PSEN1,PARK7,LMNA,CFLAR,RRN3,DAPK1,NOC2L,PARL,ARHGEF2,BCL2,TMBIM1,HTRA2,PPIF,PGAP2,TNFAIP3,RB1CC1,ZMYND11,VDAC2,RFFL,MCL1,BRCA1,SYVN1,PTTG1IP,SLC25A5,FADD,HSPA1B,FAS,SIAH2,HMGB2,TRIM32,CLU,ARRB2,IGBP1,ZC3HC1 |
| 6.318e-03 | -5.06 | GSE37533_PPARG1_FOXP3_VS_FOXP3_TRANSDUCED_CD4_TCELL_DN | MSigDB lists | GSE37533_PPARG1_FOXP3_VS_FOXP3_TRANSDUCED_CD4_TCELL_DN | 190 | 42 | 17377 | 2626 |
DDX58,MAX,CYLD,PARP12,HLA-E,TAP1,ARID5A,BTN3A1,HLA-A,GOLM1,CTNNBL1,SP100,ZCCHC2,TAP2,FBXL7,PPA1,TMBIM1,TRIM14,BAK1,TRAFD1,LAP3,BAZ2A,PARP4,DNAJA1,OGFR,LY6E,PSMB9,ISG15,RHBDF2,OPTN,HLA-B,VEZF1,TRIM26,STAT1,SIAH2,PML,EHD4,RPS6KC1,APOL2,ZC3HAV1,IFI16,RNF114 |
| 6.318e-03 | -5.06 | GSE7460_WT_VS_FOXP3_HET_ACT_TCONV_DN | MSigDB lists | GSE7460_WT_VS_FOXP3_HET_ACT_TCONV_DN | 190 | 42 | 17377 | 2626 |
WSB2,ATXN3,TM9SF4,SEC61G,ZBTB37,MCCC1,AGFG1,TMED3,RAB6A,TMEM165,CDC73,MAD2L2,ZNF428,UBXN2A,AHCTF1,VMP1,PTPN11,PARL,ANKRD13C,APOOL,UBE3C,F2R,PCBP2,JMJD4,ACP2,MLEC,CDC123,USP42,KRAS,IL12RB1,DCUN1D5,PPWD1,FXR1,EIF4G2,PPP2CA,TAF2,TMEM168,NSMCE2,PTAR1,TAF12,COPS6,CHPT1 |
| 6.318e-03 | -5.06 | GSE43955_1H_VS_60H_ACT_CD4_TCELL_WITH_TGFB_IL6_UP | MSigDB lists | GSE43955_1H_VS_60H_ACT_CD4_TCELL_WITH_TGFB_IL6_UP | 190 | 42 | 17377 | 2626 |
IER2,RAC1,UCK2,LAMTOR3,GYG1,ARF1,ATP6V1B2,RPL23A,MAN1A1,USF1,NFATC3,DPYSL2,IL6ST,LPIN2,HADHB,FAM89B,RPL19,GNAI2,TMX1,TERF2,ABCC1,ACSL5,PTPN18,SNX2,SIGMAR1,KIAA0930,RPL6,RPS10,PFKFB3,TOR1AIP2,GORASP2,CAPZA2,ZFAND5,ARPC1A,JAK1,HINT1,CCDC6,PDRG1,MAPK1,HEXA,ATP6V0E1,HDAC2 |
| 6.327e-03 | -5.06 | small_intestine-duodenum-carcinoma-adenocarcinoma | COSMIC cancer mutations | small_intestine-duodenum-carcinoma-adenocarcinoma | 33 | 11 | 17385 | 2587 |
GNAS,CDKN2C,FGFR3,NRAS,SF3B1,MSH2,PTPN11,STK11,KRAS,SMAD4,HRAS |
| 6.330e-03 | -5.06 | phagocytic vesicle membrane | cellular component | GO:0030670 | 71 | 19 | 18223 | 2701 |
RAB11B,HLA-E,RAB7A,TAP1,RAB23,ATP6V0A1,RAB22A,HLA-A,HLA-B,RAB8A,ATP6V0B,SNAP23,DNM2,ATP6V0A2,TAP2,ATP6V0C,CORO1A,ATP6V0E1,ATP6V0D1 |
| 6.331e-03 | -5.06 | soft_tissue-smooth_muscle-leiomyosarcoma | COSMIC cancer mutations | soft_tissue-smooth_muscle-leiomyosarcoma | 42 | 13 | 17385 | 2587 |
CDKN2C,RB1,EWSR1,NRAS,NF1,PTEN,SF3B1,ETV6,STK11,KRAS,FUS,HRAS,CDKN2A |
| 6.331e-03 | -5.06 | leiomyosarcoma | COSMIC cancer mutations | leiomyosarcoma | 42 | 13 | 17385 | 2587 |
CDKN2C,RB1,EWSR1,NRAS,NF1,PTEN,SF3B1,ETV6,STK11,KRAS,FUS,HRAS,CDKN2A |
| 6.368e-03 | -5.06 | negative regulation of protein localization to cell periphery | biological process | GO:1904376 | 24 | 9 | 17256 | 2622 |
TGFB1,PPP2R5A,CSK,GOPC,BCL2L1,PICALM,TMBIM1,NUMB,SAPCD2 |
| 6.368e-03 | -5.06 | protein alpha-1,2-demannosylation | biological process | GO:0036508 | 24 | 9 | 17256 | 2622 |
RPS27A,MAN1B1,SEL1L,SYVN1,EDEM2,RNF139,RNF5,RNF103,MAN1A1 |
| 6.368e-03 | -5.06 | protein demannosylation | biological process | GO:0036507 | 24 | 9 | 17256 | 2622 |
RPS27A,MAN1B1,SEL1L,SYVN1,EDEM2,RNF139,RNF5,RNF103,MAN1A1 |
| 6.372e-03 | -5.06 | MORF_PPP2R4 | MSigDB lists | MORF_PPP2R4 | 46 | 14 | 17377 | 2626 |
PDCD6,TMED10,PSMD8,SIVA1,BANF1,RAD23B,BUD31,TMEM147,NDUFB1,CDIPT,PSMC1,TMED2,SLC25A1,PSMC4 |
| 6.372e-03 | -5.06 | REACTOME_AUTODEGRADATION_OF_THE_E3_UBIQUITIN_LIGASE_COP1 | MSigDB lists | REACTOME_AUTODEGRADATION_OF_THE_E3_UBIQUITIN_LIGASE_COP1 | 46 | 14 | 17377 | 2626 |
PSMD2,PSMD1,PSMA6,PSMA8,RPS27A,PSMD8,PSMD3,PSMB7,PSMA1,PSMB9,PSMD9,PSMC1,PSMB3,PSMC4 |
| 6.372e-03 | -5.06 | HALLMARK_REACTIVE_OXIGEN_SPECIES_PATHWAY | MSigDB lists | HALLMARK_REACTIVE_OXIGEN_SPECIES_PATHWAY | 46 | 14 | 17377 | 2626 |
CAT,HHEX,FTL,GCLM,TXN,NQO1,PDLIM1,NDUFB4,PFKP,PRDX1,ABCC1,SRXN1,PRNP,GPX4 |
| 6.372e-03 | -5.06 | KEGG_NOTCH_SIGNALING_PATHWAY | MSigDB lists | KEGG_NOTCH_SIGNALING_PATHWAY | 46 | 14 | 17377 | 2626 |
NCOR2,ADAM17,KAT2A,APH1A,DTX4,MFNG,NOTCH2,DVL1,RBPJ,MAML1,PSEN1,HDAC2,DVL2,NUMB |
| 6.372e-03 | -5.06 | GO_REGULATION_OF_ESTABLISHMENT_OF_PROTEIN_LOCALIZATION_TO_PLASMA_MEMBRANE | MSigDB lists | GO_REGULATION_OF_ESTABLISHMENT_OF_PROTEIN_LOCALIZATION_TO_PLASMA_MEMBRANE | 46 | 14 | 17377 | 2626 |
PDPK1,KIF5B,RHOG,PPP2R5A,CSK,GOPC,ACSL3,ITGB1,NKD2,CIB1,EZR,BCL2L1,APPL1,TMBIM1 |
| 6.372e-03 | -5.06 | GNF2_PTPN6 | MSigDB lists | GNF2_PTPN6 | 46 | 14 | 17377 | 2626 |
HLA-B,CORO7,WAS,FAM49B,HLA-E,STAT6,EMP3,ARHGDIB,CORO1A,LYN,CRLF3,GIT2,ANXA11,HLA-A |
| 6.376e-03 | -5.06 | regulation of dephosphorylation | biological process | GO:0035303 | 200 | 44 | 17256 | 2622 |
PPP1R37,ZCCHC9,PPP1R2,PPP1R12A,PPP1R15B,ENSA,PPP1R16B,CALM2,PPP1R3B,FKBP1A,UBXN2A,MTMR4,PIN1,PPP1R8,PPME1,PPP4R1,PPP1R12C,NSFL1C,CRY2,GNAI2,PPP6R1,CHP1,ANKLE2,TGFB1,SHOC2,PPP1R9B,GBA,CDCA2,WDR81,PKMYT1,SYMPK,PLEKHF2,MASTL,MTMR3,TSC1,PPP2R5A,NSMF,UBXN2B,PPP1R11,CABIN1,ROCK1,PPP6R3,IGBP1,PPP2R2D |
| 6.382e-03 | -5.05 | autophagy of nucleus | biological process | GO:0044804 | 20 | 8 | 17256 | 2622 |
ATG9A,ATG3,ATG2B,ATG13,WIPI2,WDR45B,BECN1,ATG4A |
| 6.382e-03 | -5.05 | negative regulation of mRNA splicing, via spliceosome | biological process | GO:0048025 | 20 | 8 | 17256 | 2622 |
HNRNPA2B1,RBM42,RBMX,SRSF6,SRSF4,RNPS1,TRA2B,SRSF10 |
| 6.382e-03 | -5.05 | endoplasmic reticulum mannose trimming | biological process | GO:1904380 | 20 | 8 | 17256 | 2622 |
SYVN1,EDEM2,RPS27A,RNF139,RNF103,MAN1B1,RNF5,SEL1L |
| 6.391e-03 | -5.05 | Notch signaling pathway | KEGG pathways | hsa04330 | 48 | 15 | 7161 | 1149 |
NCOR2,ADAM17,KAT2A,APH1A,DTX4,MFNG,RBPJ,DVL1,NOTCH2,MAML1,APH1B,PSEN1,DVL2,NUMB,HDAC2 |
| 6.391e-03 | -5.05 | Notch signaling pathway | KEGG pathways | ko04330 | 48 | 15 | 7161 | 1149 |
NCOR2,ADAM17,KAT2A,APH1A,DTX4,MFNG,RBPJ,DVL1,NOTCH2,MAML1,APH1B,PSEN1,DVL2,NUMB,HDAC2 |
| 6.391e-03 | -5.05 | MORF_IKBKG | MSigDB lists | MORF_IKBKG | 131 | 31 | 17377 | 2626 |
KDM3B,TSTA3,PRKCSH,HMGXB3,LDB1,RBM8A,CIB1,CAMSAP1,CSNK2A1,MTX1,PMF1,ORC1,PKMYT1,PCGF1,PARN,TUBGCP2,POLR2A,GTF2F1,RXRB,RPA2,ARHGEF1,PML,CRCP,TCOF1,COPS6,USP11,B4GALT3,WDR62,CSNK1D,NUDT3,DDB1 |
| 6.391e-03 | -5.05 | GO_MAINTENANCE_OF_CELL_NUMBER | MSigDB lists | GO_MAINTENANCE_OF_CELL_NUMBER | 131 | 31 | 17377 | 2626 |
TRIM8,POLR2I,KLF10,POLR2G,POLR2L,POLR2K,ASPM,RAF1,LDB1,POLR2D,RTF1,LRP5,NOTCH2,SOX4,SRRT,FOXO3,METTL3,CDC73,POLR2A,PAF1,SMAD2,SMC3,PCM1,EIF4ENIF1,POLR2J,MED10,METTL14,CTR9,RBPJ,STAT3,SMAD4 |
| 6.392e-03 | -5.05 | adherens junction | cellular component | GO:0005912 | 532 | 100 | 18223 | 2701 |
RHOG,PDCD6IP,ADD1,RPLP2,ADAM10,RAC1,ACTR3,ZFYVE21,MYH9,LYN,CPNE3,GIT2,GNB2,PARK7,DST,DLG5,RAB21,CDC42,SYNM,SH3BP1,DNM2,SENP1,CFL1,PCBP2,CHP1,PTPRK,LAP3,RPL38,EZR,CADM1,STX16,RPS9,ALKBH6,AFDN,AHNAK,JAK1,RPS14,CORO1C,LIMK1,ITGB1,RPLP1,ADAM9,ATP6V0C,ACTB,MAPK1,CAPN1,PARD3,NUMB,PPIB,RPS15,RPS2,PPP1R12A,ANXA6,FLOT1,LAMTOR3,CDCA3,KIF23,SLC4A2,ARF1,NCKAP1,ITGB5,PIP5K1C,CAPN2,CD59,FGFR3,TNS3,VASP,ARPC5,ANXA5,ARHGEF2,RPL19,CNN2,PABPC1,PDPK1,CYFIP1,CYTH1,PPP1R9B,DCAF6,ADAM17,RHOA,FOCAD,CSRP1,RPL6,RPL8,RPS10,KRAS,PLEC,EIF4G2,MAP2K2,RHOB,MAPK3,HSPA1B,CAT,SCARB2,GNA12,PDLIM1,SNAP23,YWHAZ,CD81,PDLIM5 |
| 6.401e-03 | -5.05 | GSE6269_E_COLI_VS_STAPH_AUREUS_INF_PBMC_DN | MSigDB lists | GSE6269_E_COLI_VS_STAPH_AUREUS_INF_PBMC_DN | 163 | 37 | 17377 | 2626 |
CDS2,RAF1,FAM129A,TOR3A,RAC1,COPE,TGOLN2,ARF1,FKBP2,SLC25A44,RGS2,SRRT,PHC2,APLP2,ATP6V0B,PPP4R1,RRBP1,RPN2,PDIA6,STAT3,IMPA2,S100A6,MYO5A,NAGPA,SLC26A6,ARPC1A,SH3GLB1,NEU1,MYO1F,MAN2A2,TPD52L2,TFE3,ADAM9,IMPDH1,PDXK,CLN3,CHPF2 |
| 6.417e-03 | -5.05 | follicular_carcinoma | COSMIC cancer mutations | follicular_carcinoma | 61 | 17 | 17385 | 2587 |
NRAS,VHL,SF3B1,KRAS,MEN1,EML4,GNAS,RB1,FGFR3,PTEN,CCDC6,PTPN11,STK11,TFG,HRAS,SMAD4,CDKN2A |
| 6.417e-03 | -5.05 | thyroid-carcinoma-follicular_carcinoma | COSMIC cancer mutations | thyroid-carcinoma-follicular_carcinoma | 61 | 17 | 17385 | 2587 |
NRAS,VHL,SF3B1,KRAS,MEN1,EML4,GNAS,RB1,FGFR3,PTEN,CCDC6,PTPN11,STK11,TFG,HRAS,SMAD4,CDKN2A |
| 6.420e-03 | -5.05 | human chr1p34.1 | chromosome location | human chr1p34.1 | 57 | 13 | 26185 | 2809 |
TMEM69,PLK3,ATP6V0B,MMACHC,NASP,HPDL,GPBP1L1,UROD,KIF2C,MAST2,ERI3,PRDX1,B4GALT2 |
| 6.427e-03 | -5.05 | GO_NEGATIVE_REGULATION_OF_DNA_METABOLIC_PROCESS | MSigDB lists | GO_NEGATIVE_REGULATION_OF_DNA_METABOLIC_PROCESS | 105 | 26 | 17377 | 2626 |
TGFB1,DNAJC2,ERCC1,THOC1,TRIP12,HELB,GTPBP4,CDC6,MEN1,BLM,TTF1,TRIM28,XRCC5,TERF2IP,SMC3,PML,MSH2,CHEK2,ZNF830,OGG1,POT1,TERF1,RNF169,MSH6,POLQ,TERF2 |
| 6.427e-03 | -5.05 | GGAMTNNNNNTCCY_UNKNOWN | MSigDB lists | GGAMTNNNNNTCCY_UNKNOWN | 105 | 26 | 17377 | 2626 |
HSPH1,MAX,TMEM115,CLSPN,ADO,NFATC2IP,AKT1S1,NUTF2,INO80E,USP48,STMN1,SYMPK,MTR,NCDN,PA2G4,ZNF420,TBC1D17,TTLL4,CD3EAP,MEA1,FAM122A,ST3GAL2,NCLN,GPD1L,CFL1,ABCC5 |
| 6.431e-03 | -5.05 | DNA insertion or deletion binding | molecular function | GO:0032135 | 6 | 4 | 17224 | 2647 |
PCNA,MSH6,PMS2,MSH2 |
| 6.431e-03 | -5.05 | Y-form DNA binding | molecular function | GO:0000403 | 6 | 4 | 17224 | 2647 |
BLM,RAD18,MEN1,MSH2 |
| 6.435e-03 | -5.05 | GCM_HDAC1 | MSigDB lists | GCM_HDAC1 | 37 | 12 | 17377 | 2626 |
HMGN1,NASP,ANXA6,SIGMAR1,TIMM17A,DRAP1,ARHGEF1,SRSF3,TCEA1,MEN1,CBFB,HNRNPM |
| 6.435e-03 | -5.05 | GNF2_VAV1 | MSigDB lists | GNF2_VAV1 | 37 | 12 | 17377 | 2626 |
VAV1,HLA-B,CYTIP,CORO7,WAS,CSK,HLA-E,STAT6,OSTF1,ARHGDIB,CORO1A,GIT2 |
| 6.435e-03 | -5.05 | BIOCARTA_MET_PATHWAY | MSigDB lists | BIOCARTA_MET_PATHWAY | 37 | 12 | 17377 | 2626 |
CRKL,RAP1A,PTEN,RAF1,ITGB1,PTPN11,ELK1,STAT3,MAPK1,HRAS,MAP2K2,MAPK3 |
| 6.435e-03 | -5.05 | HERNANDEZ_MITOTIC_ARREST_BY_DOCETAXEL_1_DN | MSigDB lists | HERNANDEZ_MITOTIC_ARREST_BY_DOCETAXEL_1_DN | 37 | 12 | 17377 | 2626 |
DTL,RBL1,DPYSL2,SDC2,CDC6,SLC29A1,RGS2,CDK2,UBE2C,TUBB,MAN1A1,FBXO5 |
| 6.435e-03 | -5.05 | BOYAULT_LIVER_CANCER_SUBCLASS_G12_UP | MSigDB lists | BOYAULT_LIVER_CANCER_SUBCLASS_G12_UP | 37 | 12 | 17377 | 2626 |
SCAMP3,TTC13,RBM34,TOR3A,FBXW2,GORASP2,ARF1,SLC29A1,RCOR3,RPS6KC1,YY1AP1,CHKA |
| 6.463e-03 | -5.04 | MRPL28 (mitochondrial ribosomal protein L28) | protein interactions | 10573 | 70 | 20 | 17029 | 2761 |
MRPL9,MRPL42,MRPL39,MRPL12,CUL3,MRPL16,MRPL19,APP,MRPL50,MRPL2,MRPL55,GRSF1,MRPL27,MRPL34,MRPL40,MRPL13,MRPL3,MRM3,MRPL57,MRPL32 |
| 6.463e-03 | -5.04 | CCDC93 (coiled-coil domain containing 93) | protein interactions | 54520 | 70 | 20 | 17029 | 2761 |
COMMD10,MAX,RPRD1A,RCOR1,NUF2,COMMD5,FXR1,PSMD9,COMMD6,COMMD4,COMMD8,GIT2,HMG20A,OIP5,VPS26C,GRIPAP1,RABGAP1L,ARNTL,LTN1,VPS29 |
| 6.463e-03 | -5.04 | UIMC1 (ubiquitin interaction motif containing 1) | protein interactions | 51720 | 70 | 20 | 17029 | 2761 |
CPNE1,SUMO2,BABAM1,WBP2,RIOX2,BRCA1,THNSL1,BLM,COMMD8,WDR48,RAD23A,MDM2,CCNA2,HSPA4,BABAM2,SPATA2,ABRAXAS2,CAPZA1,ECPAS,DVL2 |
| 6.471e-03 | -5.04 | SEC22B (SEC22 homolog B, vesicle trafficking protein (gene/pseudogene)) | protein interactions | 9554 | 84 | 23 | 17029 | 2761 |
SART1,SEPT9,UBXN1,SCFD2,C19orf25,TMEM216,ADRB2,MCM2,GOSR1,SDHA,LMNA,RPA1,RPA2,DERL1,NAPG,TMED10,STX18,SUCLG2,SEPT11,TCOF1,TMEM9,UBE2M,VPS29 |
| 6.471e-03 | -5.04 | SLC25A41 (solute carrier family 25 member 41) | protein interactions | 284427 | 84 | 23 | 17029 | 2761 |
RAB14,GNG7,MAP4K4,EPN1,BOLA1,ARHGEF12,PAWR,LYN,REPS1,PICALM,NUDT19,PCM1,ADD3,INPP5A,MFAP1,BTF3L4,RP2,CORO1A,C12orf75,HRAS,NSUN4,RPRD1B,CSNK1G3 |
| 6.471e-03 | -5.04 | Mis12 (MIS12 kinetochore complex component) | protein interactions | 67139 | 84 | 23 | 17029 | 2761 |
MECP2,ABCF2,HNRNPF,MYNN,NUF2,PMF1,TRIM28,CBX3,SF3B2,CAT,SUGP1,DNAJC10,GALNT2,PDCD6,MED8,DSN1,SEC24C,TTC9C,AKAP8,MRPS27,PDS5B,GCC1,GPATCH4 |
| 6.471e-03 | -5.04 | IDE (insulin degrading enzyme) | protein interactions | 3416 | 84 | 23 | 17029 | 2761 |
LIME1,PPCS,LYRM4,LYRM1,GSPT2,LDHA,CHCHD2,PAWR,FAM136A,XPNPEP3,APP,PEX5,UCHL5,CHCHD1,STAT1,NSFL1C,MIA2,ATP5F1A,SPRYD4,ATP6V1C1,STAT3,EYA2,LDHB |
| 6.471e-03 | -5.04 | FOXG1 (forkhead box G1) | protein interactions | 2290 | 84 | 23 | 17029 | 2761 |
NDUFV2,SNRNP200,BTAF1,NSDHL,HNRNPUL2,MYO9B,DDX39A,SYMPK,FOXO3,NUP205,ZMYM3,SMAD2,SMC3,POLE,MAGT1,RRBP1,AKAP8,SMPD4,SMAD1,SMAD4,HDAC2,EEF1D,SMC4 |
| 6.471e-03 | -5.04 | KHSRP (KH-type splicing regulatory protein) | protein interactions | 8570 | 84 | 23 | 17029 | 2761 |
STAU1,STRIP1,SUZ12,RAE1,CIRBP,CUL3,CUL1,CHCHD2,BRCA1,MCM2,MPG,PARN,SYMPK,ASF1B,CAND1,HUWE1,PRDX5,TARDBP,CRY2,NAP1L4,CDK2,CD81,HTRA2 |
| 6.479e-03 | -5.04 | BILANGES_SERUM_AND_RAPAMYCIN_SENSITIVE_GENES | MSigDB lists | BILANGES_SERUM_AND_RAPAMYCIN_SENSITIVE_GENES | 65 | 18 | 17377 | 2626 |
EIF3L,PTMS,RPL29,RPS10,RPL6,RPL8,RPL15,RPS24,RPL27A,RPS9,EIF3H,RPL32,RPS27A,QARS,RPS14,COX7A2L,FAU,LTA4H |
| 6.492e-03 | -5.04 | CDT1 association with the CDC6:ORC:origin complex | REACTOME pathways | R-HSA-68827 | 60 | 18 | 10287 | 1696 |
PSMD2,PSMD1,PSMA6,PSMA8,RPS27A,PSMD8,PSMD3,CDT1,PSMB7,PSMA1,CDC6,ORC1,ORC3,PSMB9,PSMD9,PSMC1,PSMB3,PSMC4 |
| 6.513e-03 | -5.03 | negative regulation of macromolecule biosynthetic process | biological process | GO:0010558 | 1476 | 258 | 17256 | 2622 |
RORB,TXN,ZNF496,MAX,H2AFZ,KDM4A,TSC22D3,TRIM11,YTHDF3,SIRT2,UBE2I,RBM4,CREM,CDK5,PA2G4,CIPC,EIF4A3,GLIS2,ZNF639,METTL14,JAZF1,ETV6,NOC2L,CRY2,FNIP2,SMARCE1,DNMT1,ARID4A,CCAR1,RYBP,PTPRK,PLK1,PLK3,SP3,DEAF1,KLF10,AATF,PBXIP1,NCK1,BAZ2A,GABPA,VHL,EHMT1,RIOX2,EZR,DDX20,CDC6,AURKB,BRCA1,DOT1L,PAF1,BRMS1,HHEX,EIF4ENIF1,SMAD2,TONSL,RPS27A,RPS14,AXIN1,PRDX5,ZNF268,CHEK2,TFDP2,BEND6,POT1,HDAC2,PDCD4,ZNF564,UBE2D3,PHB2,CENPF,CTCF,TIA1,MEF2A,EIF2AK4,DNAJB1,PSEN1,METTL3,CDC73,TTF1,CNOT3,LYAR,TFAP4,RB1,MLX,SMC3,NFATC3,MEX3C,KLF16,MBD2,HDAC7,ZNF746,PHF14,DAPK1,CTR9,TIMELESS,MDFIC,YBX1,MCPH1,TNRC18,TERF2,ZNF189,ETV3,FOXK1,CREG1,ZMYND11,CIC,MTA2,LDB1,GTPBP4,ITM2A,BCLAF1,EIF2AK1,RTF1,ARID1A,CBFA2T2,FXR1,DAPK3,ZNF174,PHF6,XRCC5,TSC1,EPRS,PFDN5,SYNCRIP,ETS2,QARS,NFIL3,SIAH2,ZFP90,RUVBL2,YY1,ZNF830,CDK2,TOB1,RNF139,N4BP2L2,CDKN2A,MBD1,ZNF296,DNMT3A,MPHOSPH8,FOXM1,SUZ12,UBR2,MAGED1,WDTC1,SMARCA4,IRF3,RCOR3,DUSP22,MXD1,PAIP2,HNRNPA2B1,SPINDOC,SAP130,ZBTB21,MDM2,SHC1,SP100,MTA1,CDKN1B,ATF2,RBM15,STRAP,CGGBP1,RLIM,MOSPD1,SAP30,FAM172A,ZNF500,ERF,EID1,PGGT1B,BTG2,DRAP1,PCGF6,CIRBP,CUL3,ATXN1,NFATC2,H2AFV,MBD3,TRIM28,CHCHD3,ZNF282,RBL1,HNRNPR,MAFK,HIPK2,STAT6,ARNTL,H2AFX,DNAJC17,STAT1,BEND3,H3F3A,SMAD4,LRP8,CBX4,DNAJC2,UNK,NCOR2,DEPDC1,DAP,MECP2,TCF3,AGO2,ARID5A,PAWR,NKRF,MXD4,BLM,HMG20A,FOXO3,MAD2L2,WWP2,PTPN2,SUV39H2,KMT5A,H2AFY,BRD7,CITED2,CNOT6L,CREB1,STAT3,NCOA2,RBM15B,TSHZ1,TGFB1,SAMD4B,BTAF1,PSPC1,ZNF202,ILF3,RCOR1,ZP3,PRMT2,MEN1,CBX3,CNOT9,UPF1,BIRC5,GPS2,ZHX1,PITX1,E2F1,PML,KHSRP,HMGB2,DDX5,RBPJ,NR2F2,IGBP1,CPEB2,PURA,TERF1,IFI16 |
| 6.522e-03 | -5.03 | SPINT2 (serine peptidase inhibitor, Kunitz type 2) | protein interactions | 10653 | 108 | 28 | 17029 | 2761 |
NOP9,ZDHHC18,NDC1,TMUB1,ABCA3,TSC2,C1orf112,CCZ1,TYW1,TIGD5,SMC2,TAF6L,PKMYT1,CMTM6,APP,TUBGCP2,ZNF696,ARL6IP6,ASPHD2,GTPBP3,NUS1,ITPRIPL1,WDR44,OSBPL8,KIF14,ZDHHC13,UPK3BL1,MZT2B |
| 6.525e-03 | -5.03 | GSE9960_GRAM_NEG_VS_GRAM_NEG_AND_POS_SEPSIS_PBMC_DN | MSigDB lists | GSE9960_GRAM_NEG_VS_GRAM_NEG_AND_POS_SEPSIS_PBMC_DN | 174 | 39 | 17377 | 2626 |
RWDD1,NDUFB6,DAP,CHCHD2,GMCL1,NENF,SLC35B2,CDIPT,CCNB1,SLC25A43,NRF1,ZNF473,ZNHIT6,SSBP3,C8orf59,ZRANB1,FGFR1OP2,NCOA2,ZNF583,VPS13B,ZNF780B,CPOX,LRBA,CRNKL1,GORASP2,KIAA1586,GALNT7,PWWP2B,BOLA3,ATAD2,HINT1,SNAP23,KLHL15,TRIM52,RUVBL2,C11orf1,SLC25A39,TSEN15,S100PBP |
| 6.525e-03 | -5.03 | BROWNE_HCMV_INFECTION_48HR_UP | MSigDB lists | BROWNE_HCMV_INFECTION_48HR_UP | 174 | 39 | 17377 | 2626 |
TMEM106C,POLA2,H2AFZ,DHX9,HMGN3,PAWR,PPP3CB,ATP6V1B2,NUP205,EPM2A,MBD4,OIP5,NFATC3,MSH2,NUP153,SAP30,RFC3,CELSR2,GABPA,PPT1,ZNF202,MRS2,AMD1,EZR,OTUD3,BRCA1,NFATC2IP,CCNF,SLC25A5,MAN2A2,FBXO28,ZNF330,GADD45B,PRPS2,CCDC69,CLN3,RAD51D,PFKP,ZC3HAV1 |
| 6.525e-03 | -5.03 | GSE37301_HEMATOPOIETIC_STEM_CELL_VS_RAG2_KO_NK_CELL_DN | MSigDB lists | GSE37301_HEMATOPOIETIC_STEM_CELL_VS_RAG2_KO_NK_CELL_DN | 174 | 39 | 17377 | 2626 |
SEPHS2,DAP,PRKAA1,JMJD6,GLUD1,DNAJB1,NCKAP1,RGS2,STMN1,ETS1,SCYL2,RGS1,DPYSL2,OSTF1,CITED2,FDFT1,PLK3,TNFAIP3,PBXIP1,NEK7,BTG2,SLBP,WDR82,CBFA2T2,ZFAND5,KLF6,POLG2,RHOB,MYO1F,MTMR3,AHNAK,MID1IP1,AGPAT2,DCK,ITGB1,PGRMC1,SLC16A1,ANP32E,CWC25 |
| 6.573e-03 | -5.02 | WDR76 (WD repeat domain 76) | protein interactions | 79968 | 52 | 16 | 17029 | 2761 |
CCT2,PPIB,PCGF6,CUL3,MYH9,CAPZA2,FXR1,CCT8,RPSA,SUPT16H,XRCC5,IMPDH1,LRRC59,SSSCA1,ZC3HAV1,SSRP1 |
| 6.573e-03 | -5.02 | LBR (lamin B receptor) | protein interactions | 3930 | 52 | 16 | 17029 | 2761 |
MECP2,TCF3,DHX9,TMEM216,LUC7L,DHX15,LMNA,EVC2,CBX3,CLK3,HNRNPR,EIF4A3,PSMD3,CHTOP,ARRB2,SRPK2 |
| 6.573e-03 | -5.02 | CCNA1 (cyclin A1) | protein interactions | 8900 | 52 | 16 | 17029 | 2761 |
RB1,CCNA2,RBL1,GPS2,ARID2,CDT1,E2F1,MYBL2,CUL1,CDKN1B,BRCA1,COPS6,CDK2,CABLES1,RBM4,RPA1 |
| 6.573e-03 | -5.02 | PLEKHO1 (pleckstrin homology domain containing O1) | protein interactions | 51177 | 52 | 16 | 17029 | 2761 |
USP7,STAU1,AKT2,CSNK2A1,DNAJB1,CAPZA2,FXR1,NVL,NOC2L,CAPZA1,KBTBD7,DDX31,PDCD11,WDR45B,SMURF1,FTSJ3 |
| 6.580e-03 | -5.02 | transcription factor activity, transcription factor binding | molecular function | GO:0000989 | 209 | 46 | 17224 | 2647 |
RORB,POU3F2,ZNF296,TRERF1,DHX9,SMARCA4,MED13L,MEF2A,THRAP3,NOTCH2,DNAJB1,SNAPC4,CDC73,TTF1,WWP2,MED8,MED10,CRY2,CITED2,CREB1,ATF2,MYBL1,MED22,CARM1,CDC5L,POU2AF1,MTA2,LDB1,RIOX2,MYBL2,WBP2,RTF1,BRCA1,SOX4,TRIM28,TAF2,HIPK2,PITX1,MED15,ARNTL,NCOA1,BEND6,YY1,SMAD4,SGF29,N4BP2L2 |
| 6.586e-03 | -5.02 | NDUFA11 (NADH:ubiquinone oxidoreductase subunit A11) | protein interactions | 126328 | 39 | 13 | 17029 | 2761 |
COX5B,NDUFA5,NDUFV2,NDUFV1,NDUFS1,NDUFA2,NDUFB6,NDUFB4,UQCR10,NDUFS8,NDUFS5,NDUFS7,NDUFS4 |
| 6.586e-03 | -5.02 | MAT2B (methionine adenosyltransferase 2B) | protein interactions | 27430 | 39 | 13 | 17029 | 2761 |
PPP3CA,TNS3,KPNA4,NASP,TSTA3,CNN2,MCM2,EIF5,PDIA6,EIF4H,APP,MAT2A,TUBB |
| 6.586e-03 | -5.02 | DUSP4 (dual specificity phosphatase 4) | protein interactions | 1846 | 39 | 13 | 17029 | 2761 |
SRM,PRDX5,TNPO3,ABHD14B,COA7,AP3S1,MAPK14,MAPK1,SDHA,PARK7,APP,VPS29,MAPK3 |
| 6.586e-03 | -5.02 | ARFIP2 (ADP ribosylation factor interacting protein 2) | protein interactions | 23647 | 39 | 13 | 17029 | 2761 |
HGS,EWSR1,AGTRAP,ARF5,RAC1,ARFIP2,CEP63,ARF1,DUSP22,PDLIM5,STAT3,APP,CDKN2A |
| 6.586e-03 | -5.02 | UBXN10 (UBX domain protein 10) | protein interactions | 127733 | 39 | 13 | 17029 | 2761 |
SDHB,CLUAP1,UBXN2A,HSPB11,RAE1,NSFL1C,IFT27,WDR45B,SDHA,IFT46,APP,NPLOC4,ALDH9A1 |
| 6.586e-03 | -5.02 | OGDH (oxoglutarate dehydrogenase) | protein interactions | 4967 | 39 | 13 | 17029 | 2761 |
UNK,MDM2,SUCLG1,MRPS2,COX5A,SUCLG2,CAPZA2,CYC1,MRPL13,PDHX,ISG15,NDUFS4,USP13 |
| 6.586e-03 | -5.02 | CDA (cytidine deaminase) | protein interactions | 978 | 39 | 13 | 17029 | 2761 |
CPNE1,CDKN2C,CLIC4,WDYHV1,DPYSL2,PSMA1,MTMR6,KPNA2,MCM2,CPNE3,ZNF598,PFKP,ZBTB24 |
| 6.586e-03 | -5.02 | EGLN1 (egl-9 family hypoxia inducible factor 1) | protein interactions | 54583 | 39 | 13 | 17029 | 2761 |
RHOBTB3,SNUPN,CBWD2,AKT2,VHL,SIAH2,CBWD1,KRAS,FKBP5,PTGES3,PKM,POLR2A,EGLN1 |
| 6.586e-03 | -5.02 | MYH7 (myosin heavy chain 7) | protein interactions | 4625 | 39 | 13 | 17029 | 2761 |
KEAP1,SEC61B,PDCD6,ATP6V1D,CLSPN,PRDX5,PPP3R1,CDCA8,AFF1,RBPJ,ECD,ECPAS,SPTAN1 |
| 6.590e-03 | -5.02 | SCHLOSSER_SERUM_RESPONSE_UP | MSigDB lists | SCHLOSSER_SERUM_RESPONSE_UP | 126 | 30 | 17377 | 2626 |
PDPK1,RHOG,CSNK1G2,KIF3B,ORAI2,ELL2,PIGQ,MAP4K4,ACAP1,MXD4,MYO9B,STX16,GNB2,CNOT3,DOT1L,KIFC1,BRD2,SCAP,CSK,STAT6,ARHGEF2,AP1S1,PPP1R11,BCL2,BTF3,STAT3,ATP6V0D1,RAD51D,N4BP2L2,SPTAN1 |
| 6.602e-03 | -5.02 | GSE3720_VD1_VS_VD2_GAMMADELTA_TCELL_WITH_PMA_STIM_DN | MSigDB lists | GSE3720_VD1_VS_VD2_GAMMADELTA_TCELL_WITH_PMA_STIM_DN | 185 | 41 | 17377 | 2626 |
SLC12A7,RHOG,TSC22D3,DLGAP4,ABHD14B,TMED3,EZH1,CCNL2,APH1B,EXT2,XPR1,SRI,LDLRAD3,CNPY3,ATP6V0D1,TMBIM1,GM2A,KDM3B,BAZ2A,RNF25,MIER1,RFXANK,BOLA1,GALK2,ADRB2,WBP1,PRMT2,STX16,TAZ,EIF3H,ECH1,MAPK3,PI4K2A,SH3BP5,MAGED2,HAGHL,OAZ2,USP20,B4GALT3,IDH3B,USF2 |
| 6.602e-03 | -5.02 | GSE17721_CTRL_VS_GARDIQUIMOD_1H_BMDC_UP | MSigDB lists | GSE17721_CTRL_VS_GARDIQUIMOD_1H_BMDC_UP | 185 | 41 | 17377 | 2626 |
PHF23,KLHL21,SLC39A13,MYNN,GLUD1,ARGLU1,TBC1D13,SLC12A9,AKR1B1,AHDC1,OSTF1,TALDO1,CPSF4,CAMK2G,LYPLA2,PCBP2,MED22,ELOF1,PDLIM2,BAK1,AACS,GBA,RPL6,HEBP2,EMP3,TMEM147,PEF1,KDM3A,SLTM,GIGYF1,EIF3H,STOML2,HHEX,ATP1A1,LTBP4,AKNA,COPS6,RUFY3,CCNB2,NAA60,STARD3NL |
| 6.602e-03 | -5.02 | GSE21670_TGFB_VS_IL6_TREATED_CD4_TCELL_DN | MSigDB lists | GSE21670_TGFB_VS_IL6_TREATED_CD4_TCELL_DN | 185 | 41 | 17377 | 2626 |
C9orf78,ZCCHC9,SUCLG1,POLR2K,GSPT2,TRMT6,FAM76A,TMX3,ENSA,VTI1A,B4GALT1,SLC35B1,RLF,STAM,PNO1,KIF5B,MLX,NEK6,CD3EAP,COPS7B,MINPP1,CNPY3,PPA1,SENP1,IFT46,CSNK1G3,MORC3,ADAM17,POLR2I,HEMK1,TOP3A,TBRG4,TXNL4A,TSR2,DNAJC10,TMEM168,AGPAT2,PPP1R11,BRD9,BYSL,DDX42 |
| 6.602e-03 | -5.02 | GSE17721_0.5H_VS_4H_GARDIQUIMOD_BMDC_DN | MSigDB lists | GSE17721_0.5H_VS_4H_GARDIQUIMOD_BMDC_DN | 185 | 41 | 17377 | 2626 |
TM9SF4,SLC41A1,FAM53C,TOR3A,C16orf87,RAC1,DLGAP4,MYNN,LYN,MYEF2,WDR48,FBRS,RAB8A,VASP,NUS1,SLC44A1,ZNF260,PPP6C,PTPN11,LTN1,MDFIC,ATF2,ZNF189,SRSF10,SRSF11,ADAM17,ACP2,BIRC3,GABPA,C9orf40,KLF6,PLEKHF2,DTWD1,KPNA1,SYNCRIP,BRD2,TBPL1,FAM122A,RUFY3,COIL,NUMB |
| 6.602e-03 | -5.02 | GSE20500_RETINOIC_ACID_VS_RARA_ANTAGONIST_TREATED_CD4_TCELL_DN | MSigDB lists | GSE20500_RETINOIC_ACID_VS_RARA_ANTAGONIST_TREATED_CD4_TCELL_DN | 185 | 41 | 17377 | 2626 |
GCLM,ASH1L,ATXN3,TMEM41B,GSPT2,JMJD6,PSEN1,NCAPG,RGS1,PRNP,MOAP1,CAPN2,MEX3C,DCP1A,TTC4,ECD,TP53BP2,CDC37,PPIF,ERCC1,STAU1,TMEM39A,ACSL3,PFKFB3,ADRB2,MEF2D,SRSF5,RHBDF2,PI4K2A,SLC19A1,SCARB2,HGS,FBXO28,GOLGA7,ACYP1,ODF2,KPNA2,IGBP1,CCDC59,CBX4,ADNP2 |
| 6.602e-03 | -5.02 | CHANDRAN_METASTASIS_UP | MSigDB lists | CHANDRAN_METASTASIS_UP | 185 | 41 | 17377 | 2626 |
UBE2D3,ADD1,FOXM1,TRIO,STARD7,TPX2,UBE2Z,SIKE1,SECISBP2,PLXNA1,LYN,KIAA1147,RAD23B,AP2B1,PABPC1,FGFR1OP2,PCBP2,CSNK1G2,ADAM17,NOL8,TAOK1,E2F3,CAMSAP1,NFATC2IP,SEPT7,SOX4,OGFR,EML4,TARS,ABHD5,NECAP2,DDX17,EPB41,RPL37,U2SURP,SEL1L,SLC16A1,PDLIM5,CDK2,TERF1,CBX4 |
| 6.602e-03 | -5.02 | GSE25085_FETAL_BM_VS_ADULT_BM_SP4_THYMIC_IMPLANT_DN | MSigDB lists | GSE25085_FETAL_BM_VS_ADULT_BM_SP4_THYMIC_IMPLANT_DN | 185 | 41 | 17377 | 2626 |
WSB2,HIVEP3,PTMS,TRIO,KLF13,SLC35B1,RUFY1,TFRC,MAN1A1,ANXA5,BRI3,CYB5R1,NAP1L4,RNF19A,CITED2,PDIA6,CYFIP1,ADAM17,USO1,ACP2,TNFAIP3,BIRC3,SNX2,C16orf72,RFFL,PFKFB3,ARID1A,ZFAND5,KLF6,OPTN,PLD3,IDE,ETS2,AGPAT2,FAM3C,LMBR1,ZFP90,RBPJ,RUFY3,FAM208A,VPS29 |
| 6.621e-03 | -5.02 | FHA_dom | interpro domains | IPR000253 | 33 | 11 | 18492 | 2768 |
CEP170B,AFDN,STARD9,AGGF1,FOXK1,KIF14,KIF13B,PPP1R8,MKI67,CHEK2,TCF19 |
| 6.623e-03 | -5.02 | GRABARCZYK_BCL11B_TARGETS_UP | MSigDB lists | GRABARCZYK_BCL11B_TARGETS_UP | 70 | 19 | 17377 | 2626 |
SLC30A9,RECQL,USO1,PDCD6IP,NQO1,DENND1B,NEK7,GMFB,TOR1AIP2,BICD2,ANKRD46,SH3BP5,TRAM2,SCARB2,AHNAK,NUS1,JAK1,MAPK6,SLC35A1 |
| 6.624e-03 | -5.02 | SETD1B (SET domain containing 1B) | protein interactions | 23067 | 19 | 8 | 17029 | 2761 |
WDR82,SYNCRIP,WDR5,PRMT2,CXXC1,PIP4K2A,ZC3H3,POLR2A |
| 6.624e-03 | -5.02 | SHOC2 (SHOC2, leucine rich repeat scaffold protein) | protein interactions | 8036 | 19 | 8 | 17029 | 2761 |
KRAS,ERBIN,NRAS,PLCL2,HUWE1,APP,HRAS,RAF1 |
| 6.624e-03 | -5.02 | FOXD4L6 (forkhead box D4 like 6) | protein interactions | 653404 | 19 | 8 | 17029 | 2761 |
ANKRD28,FAM192A,PPP2CA,ZNF496,KIAA0232,THNSL1,GGPS1,PPP2R2D |
| 6.624e-03 | -5.02 | Cdc6 (cell division cycle 6) | protein interactions | 23834 | 19 | 8 | 17029 | 2761 |
B4GALT1,BCLAF1,CDC6,THRAP3,ZNF598,TRIM14,PDF,PRPF4B |
| 6.624e-03 | -5.02 | GLA (galactosidase alpha) | protein interactions | 2717 | 19 | 8 | 17029 | 2761 |
MAT2B,GNS,PTPN18,CNOT6,EIF5,EIF4H,CNOT11,CAPN1 |
| 6.624e-03 | -5.02 | PKMYT1 (protein kinase, membrane associated tyrosine/threonine 1) | protein interactions | 9088 | 19 | 8 | 17029 | 2761 |
PLK1,CCNA2,PTEN,PIN1,TMEM216,BCL2,CCNB1,CCNB2 |
| 6.624e-03 | -5.02 | RPL22L1 (ribosomal protein L22 like 1) | protein interactions | 200916 | 19 | 8 | 17029 | 2761 |
UNK,MDM2,PTEN,FAAP100,USP39,MCM2,COPS6,CAND1 |
| 6.626e-03 | -5.02 | ATP5PD (ATP synthase peripheral stalk subunit d) | protein interactions | 10476 | 61 | 18 | 17029 | 2761 |
COX15,TM9SF4,CHCHD2,NDUFA4,ATP5F1B,FAM136A,OGDH,RAB1A,VDAC1,SDHA,APP,STOML2,USF1,ZFYVE27,ATP5F1A,CYC1,APOOL,TFG |
| 6.626e-03 | -5.02 | MPRIP (myosin phosphatase Rho interacting protein) | protein interactions | 23164 | 61 | 18 | 17029 | 2761 |
YTHDC1,PLK1,RHOA,PPP1R12A,MYH9,LSM8,RACGAP1,CAPZA2,ANLN,RPA1,RPA2,PCM1,PTEN,MYO18A,MIA2,PPP1R12C,CDK2,SGF29 |
| 6.626e-03 | -5.02 | CDK19 (cyclin dependent kinase 19) | protein interactions | 23097 | 61 | 18 | 17029 | 2761 |
CCNC,NIFK,FAM49B,RB1CC1,SUZ12,CUTA,MED13L,CTCF,SMARCA4,COMMD4,ERC1,MYEF2,MED8,MED10,STK38,MED15,CLU,MED22 |
| 6.636e-03 | -5.02 | PAK1 (p21 (RAC1) activated kinase 1) | protein interactions | 5058 | 113 | 29 | 17029 | 2761 |
PDPK1,NCK1,DYNLL1,RAF1,RAC1,CSNK2A1,MYNN,CDK11B,MAPK14,LYN,CDK11A,GIT2,APP,CDK5,PPP2CA,HGS,SMAD2,SHC1,FBXO28,CDC42,LIMK1,H2AFX,ARHGEF2,YWHAZ,SMAD1,MAPK1,SMURF1,SMAD4,ILKAP |
| 6.638e-03 | -5.01 | drug metabolic process | biological process | GO:0017144 | 638 | 120 | 17256 | 2622 |
ADA2,COX15,MMACHC,NDUFA5,NQO1,SUCLG1,NDUFB6,GNPDA1,UQCR10,MDH2,MCCC1,OLA1,ADPGK,OAT,ATP6V1B2,ATP5PF,SDHA,PARK7,CD320,FLAD1,CS,AKR1B1,SUCLG2,NDUFB9,AHCYL1,IDH3A,ATP6V0A1,OGDH,AMDHD2,NDUFA7,NDUFB1,TAZ,MAT2A,STOML2,ALDH3B1,IDE,NDUFA11,PRDX5,COX5A,DHTKD1,UQCRH,PDXK,DHFR2,CHPT1,CHID1,PFKP,GALK1,NDUFV2,CMAS,COX5B,NDUFS1,MUT,MECP2,MRI1,GNE,NDUFA4,COX4I1,CYCS,PM20D2,ATP5F1B,SPR,EPHX2,NDUFS7,NDUFS4,MAT2B,PDXP,NDUFV1,GART,NDUFA2,NDUFB4,BDH1,MSH2,ATP6V0A2,ABCD1,NDUFS8,AHCY,CYC1,ALDH18A1,NDUFA3,ABCC1,TGFB1,ELOVL5,GUK1,AACS,AMD1,LDHA,ADSL,VKORC1,PKM,ATP5MF,KDM3A,MTR,PRDX1,HSPA1B,SDHB,CAT,ADSS,SLC19A1,MTHFD2,ATP5MC3,PRDX3,ACOX1,PARG,PRPS2,COX7A2L,CTBS,ACLY,COX8A,ACAT1,SLC25A19,MDH1,NDUFS5,GPI,ATP5F1A,NANP,IDH3B,NIPSNAP2,PGAM1,SAT2,GCSH |
| 6.661e-03 | -5.01 | GSE21670_UNTREATED_VS_TGFB_IL6_TREATED_CD4_TCELL_DN | MSigDB lists | GSE21670_UNTREATED_VS_TGFB_IL6_TREATED_CD4_TCELL_DN | 158 | 36 | 17377 | 2626 |
GMFG,RPLP2,SEC61G,EBNA1BP2,NIT2,POMP,PMF1,EPHX2,RAB11A,DECR1,CDC42,SAR1A,RPL17,ZNHIT6,GEMIN6,TRA2B,SUCLG2,POLR1B,TMEM14C,S100A6,YTHDC1,RPL29,RFC3,PGGT1B,DPM1,LYRM1,RPL6,EIF2A,DPYSL3,ADSS,TSC1,HINT1,SYNCRIP,RPS27A,ZNF45,CCDC59 |
| 6.685e-03 | -5.01 | Collecting duct acid secretion | KEGG pathways | hsa04966 | 27 | 10 | 7161 | 1149 |
SLC12A7,ATP6V1D,ATP6V0A1,ATP6V0A2,ATP6V0C,ATP6V1C1,ATP6V1B2,ATP6V0E1,ATP6V0D1,ATP6V1G1 |
| 6.685e-03 | -5.01 | Collecting duct acid secretion | KEGG pathways | ko04966 | 27 | 10 | 7161 | 1149 |
SLC12A7,ATP6V1D,ATP6V0A1,ATP6V0A2,ATP6V0C,ATP6V1C1,ATP6V1B2,ATP6V0E1,ATP6V0D1,ATP6V1G1 |
| 6.690e-03 | -5.01 | Golgi to plasma membrane transport | biological process | GO:0006893 | 46 | 14 | 17256 | 2622 |
CCDC93,GCC2,GOLGA4,GOLPH3L,SYS1,GOLGA7,NSF,GOPC,ANK3,EXOC4,DNM2,CHIC2,MACF1,OPTN |
| 6.690e-03 | -5.01 | regulation of alternative mRNA splicing, via spliceosome | biological process | GO:0000381 | 46 | 14 | 17256 | 2622 |
RBM25,NSRP1,RBMX,SRSF6,RBM8A,SMU1,RNPS1,SREK1,TRA2B,DDX5,THRAP3,RBM4,DDX17,RBM15B |
| 6.693e-03 | -5.01 | HGS (hepatocyte growth factor-regulated tyrosine kinase substrate) | protein interactions | 9146 | 209 | 48 | 17029 | 2761 |
MIF4GD,SCAMP3,DCTN2,TRAK1,NUP54,ARFIP2,GGA2,DAZAP2,UBE2I,STAM,APP,TFRC,DECR1,APLP2,ATP2A2,ZNF302,VMP1,ARL6IP1,TTC4,AHCYL1,ILKAP,MYO5A,UBQLN4,RHOBTB3,SNX2,TIMMDC1,UBE4B,ADRB2,PEF1,ARMC8,MAT2A,MKNK1,PLD3,HSPBP1,SMAD2,ATP1A1,PITX1,CEP55,ACLY,MRFAP1L1,VPS4A,ROCK1,SMAD1,ARRB2,HNRNPDL,SMAD4,ABCA1,TUBB |
| 6.695e-03 | -5.01 | GO_CHROMATIN_REMODELING | MSigDB lists | GO_CHROMATIN_REMODELING | 142 | 33 | 17377 | 2626 |
HJURP,CHD1L,SMARCA4,TAF6L,CHD1,TTF1,ARID1B,OIP5,RB1,SUV39H2,MBD2,CENPM,TOP1MT,SMARCE1,TNRC18,BRD4,NASP,KAT2A,BAZ2A,MTA2,PBRM1,ARID1A,MBD3,CBX3,BAZ1B,ANP32E,ACTB,RUVBL2,CENPT,RBBP4,CDKN2A,HDAC2,SMARCD1 |
| 6.695e-03 | -5.01 | GO_CULLIN_RING_UBIQUITIN_LIGASE_COMPLEX | MSigDB lists | GO_CULLIN_RING_UBIQUITIN_LIGASE_COMPLEX | 142 | 33 | 17377 | 2626 |
KLHL21,KCTD17,KLHL18,CUL1,MAD2L2,ZER1,DTL,KLHL5,KLHL20,CDKN1B,ANAPC7,FBXL7,FBXL19,DCAF6,RBX1,DCAF8,CUL3,FBXO9,ANAPC2,CCNF,CDC23,CAND1,CDC16,KEAP1,CDC27,KLHL15,DCAF11,KBTBD7,FBXL3,UBE2C,DCAF5,DDB1,ANAPC4 |
| 6.709e-03 | -5.00 | GO_RECEPTOR_METABOLIC_PROCESS | MSigDB lists | GO_RECEPTOR_METABOLIC_PROCESS | 75 | 20 | 17377 | 2626 |
TGFB1,SNX25,RAB11B,EZR,ZNRF3,BECN1,PICALM,SCYL2,SH3GLB1,CDK5,FNTA,FUT8,DNM2,ITGB1,SMURF1,ARRB2,CD81,GTF2H2,ALS2,CAPN1 |
| 6.709e-03 | -5.00 | GO_POSITIVE_REGULATION_OF_AUTOPHAGY | MSigDB lists | GO_POSITIVE_REGULATION_OF_AUTOPHAGY | 75 | 20 | 17377 | 2626 |
TRIM8,SCOC,PRKAA1,PIP4K2C,GBA,EIF2AK4,ADRB2,BECN1,TRIM65,PARK7,PIP4K2A,EPM2A,SH3GLB1,MAPK3,TFEB,RALB,STK11,LRSAM1,TPCN1,SVIP |
| 6.725e-03 | -5.00 | protein localization to cytoskeleton | biological process | GO:0044380 | 37 | 12 | 17256 | 2622 |
PCM1,MAPRE1,KLHL21,CCDC14,DCTN2,FAM83D,DVL1,ANLN,MCPH1,CSNK1D,SPAG5,RTKN |
| 6.725e-03 | -5.00 | positive regulation of cytokinesis | biological process | GO:0032467 | 37 | 12 | 17256 | 2622 |
KIF3B,RHOA,PKP4,CDC42,KIF14,CUL3,KIF23,NUP62,CDC6,RACGAP1,CDC25B,AURKB |
| 6.725e-03 | -5.00 | DNA replication initiation | biological process | GO:0006270 | 37 | 12 | 17256 | 2622 |
POLA2,MCM10,PRIM2,POLE,MCM5,CDC6,ORC1,MCM2,ORC3,PURA,GINS4,PRIM1 |
| 6.728e-03 | -5.00 | SIAH1 (siah E3 ubiquitin protein ligase 1) | protein interactions | 6477 | 168 | 40 | 17029 | 2761 |
UBE2D3,UBE2E2,TXN,WDYHV1,XIAP,ZFYVE21,LACTB2,UBE2I,LMNA,PHC2,VAV1,SIAH1,KIF22,AFF1,TP53BP2,SPATC1L,STAT3,EEF1D,TERF2,RLIM,POU2AF1,ZCCHC10,TRIM8,KLF10,ELL2,RAD51AP1,CDC23,MCM2,RPL27A,TOLLIP,HIPK2,TFDP1,PML,PIAS2,SIAH2,MAP3K5,HIPK3,ZMAT3,NUMB,PARD3 |
| 6.741e-03 | -5.00 | GO_REGULATION_OF_PH | MSigDB lists | GO_REGULATION_OF_PH | 85 | 22 | 17377 | 2626 |
CLCN3,PPT1,RAB7A,SLC26A6,ATP6V0A1,SLC4A2,ATP6V1B2,TMEM165,ATP6V0B,PDK2,CLIC4,ATP6V1D,ATP6V0A2,BCL2,ATP6V0C,SLC26A2,ATP6V1C1,CLN3,CLN6,ATP6V0E1,ATP6V0D1,ATP6V1G1 |
| 6.746e-03 | -5.00 | GRAHAM_CML_QUIESCENT_VS_NORMAL_QUIESCENT_UP | MSigDB lists | GRAHAM_CML_QUIESCENT_VS_NORMAL_QUIESCENT_UP | 80 | 21 | 17377 | 2626 |
GINS1,PPIF,ANKRD27,TK1,CPOX,CENPF,KIF15,RRM2,RACGAP1,NUSAP1,SMC2,KIF11,LMNA,SAC3D1,PDLIM1,MCM5,CEP55,H2AFX,PRC1,MINPP1,CCNB2 |
| 6.746e-03 | -5.00 | PID_MET_PATHWAY | MSigDB lists | PID_MET_PATHWAY | 80 | 21 | 17377 | 2626 |
PDPK1,RHOA,NCK1,AKT2,RAF1,RAC1,AKT1S1,ETS1,MAP2K2,MAPK3,PTPN2,CRKL,RAP1A,HGS,SHC1,CDC42,PTPN11,MAPK1,HRAS,NUMB,MLST8 |
| 6.746e-03 | -5.00 | GO_REGULATION_OF_TRANSLATIONAL_INITIATION | MSigDB lists | GO_REGULATION_OF_TRANSLATIONAL_INITIATION | 80 | 21 | 17377 | 2626 |
EIF3L,POLR2G,NCK1,PPP1R15B,EIF3D,POLR2D,EIF2AK1,EIF2AK4,EIF1B,EIF4G2,EIF4H,METTL3,RBM4,EIF3G,EIF3H,EIF3A,PAIP2,EIF3K,MKNK1,GLE1,EIF5 |
| 6.804e-03 | -4.99 | GSE21678_WT_VS_FOXO1_FOXO3_KO_TREG_UP | MSigDB lists | GSE21678_WT_VS_FOXO1_FOXO3_KO_TREG_UP | 169 | 38 | 17377 | 2626 |
ZBTB10,SMAP1,IVNS1ABP,SRGN,AP3M2,VTI1A,MED13L,AGFG1,NANS,SCYL2,ARID1B,DNAJB9,FANCL,INPP5A,TP53BP2,FAM76B,SYTL3,RPRD1B,MND1,SHOC2,LONRF3,NARF,RRM2,SREK1,PNPLA8,VDAC1,ARL5B,MASTL,TAF2,SH3BP5,ATAD2,TXNDC16,KLHL15,PIAS2,MAP3K5,WDR91,EHD4,ABCA1 |
| 6.804e-03 | -4.99 | GO_OUTER_MEMBRANE | MSigDB lists | GO_OUTER_MEMBRANE | 169 | 38 | 17377 | 2626 |
TOMM20,MTX3,PHB2,RAF1,ANKH,TMEM109,LETMD1,BCL2L1,SNN,PSEN1,PRNP,MOAP1,SLC44A1,HADHB,CISD2,BCL2,MAVS,ATF2,MTX2,ACSL5,BAK1,SIGMAR1,ACSL3,VDAC2,MCL1,NUTF2,MTX1,TOMM40,VDAC1,RHOT1,RHOT2,CYB5A,SH3GLB1,MFN2,AKAP1,ANKZF1,TOMM6,LRPPRC |
| 6.823e-03 | -4.99 | Paget's disease(PMID:21623375) | GWAS genes | Paget's disease(PMID:21623375) | 7 | 4 | 2388 | 307 |
SLC25A43,NUP205,PML,OPTN |
| 6.846e-03 | -4.98 | TRIM54 (tripartite motif containing 54) | protein interactions | 57159 | 128 | 32 | 17029 | 2761 |
UBE2D3,USP7,ATXN3,THOC1,WDYHV1,ARFIP2,CHCHD2,GMCL1,UBE2I,RCOR3,STAM,CCDC28A,MEAF6,USP5,RAD23A,UCHL5,JOSD1,OSTF1,SMARCE1,DNAL4,PPP1R18,ELOA,MBD3,USP21,MAPK3,ELMO1,FAM110A,MFAP1,C1orf109,KPNA2,NGLY1,BYSL |
| 6.850e-03 | -4.98 | STPHPHTASE | prints domains | PR00114 | 13 | 5 | 4652 | 473 |
PPP2CA,PPP3CA,PPP3CB,PPP5C,PPP6C |
| 6.853e-03 | -4.98 | REACTOME_RNA_POL_II_PRE_TRANSCRIPTION_EVENTS | MSigDB lists | REACTOME_RNA_POL_II_PRE_TRANSCRIPTION_EVENTS | 51 | 15 | 17377 | 2626 |
CTDP1,POLR2I,POLR2G,POLR2L,POLR2J,POLR2K,POLR2D,TCEA1,TAF12,GTF2H2,TAF6,POLR2A,SSRP1,SUPT16H,GTF2F1 |
| 6.853e-03 | -4.98 | PID_KIT_PATHWAY | MSigDB lists | PID_KIT_PATHWAY | 51 | 15 | 17377 | 2626 |
CRKL,PDPK1,VAV1,SHC1,PTEN,RAF1,STAT1,PTPN11,BCL2,LYN,STAT3,FOXO3,HRAS,MAP2K2,MAPK3 |
| 6.853e-03 | -4.98 | HU_GENOTOXIN_ACTION_DIRECT_VS_INDIRECT_24HR | MSigDB lists | HU_GENOTOXIN_ACTION_DIRECT_VS_INDIRECT_24HR | 51 | 15 | 17377 | 2626 |
HLA-B,RB1,MIF4GD,HSPB11,NUS1,SYNCRIP,FASTK,HNRNPUL2,EMP3,TCEA1,GLRX3,API5,SLC50A1,LYPLA2,TMX1 |
| 6.853e-03 | -4.98 | GCM_NUMA1 | MSigDB lists | GCM_NUMA1 | 51 | 15 | 17377 | 2626 |
MOB4,SAP130,SAMD4B,KDM3B,SNRNP200,BAZ2A,GORASP1,MTMR4,VPS26B,ZNF512,SAFB,PRDM4,TNPO2,TTC17,ABHD16A |
| 6.853e-03 | -4.98 | GO_CATION_TRANSPORTING_ATPASE_ACTIVITY | MSigDB lists | GO_CATION_TRANSPORTING_ATPASE_ACTIVITY | 51 | 15 | 17377 | 2626 |
ATP6V0B,ATP13A1,ATP1A1,ATP2A2,ATP2C1,ATP13A3,ATP6V0A1,ANXA5,ATP6V0A2,ATP6V0C,ATP6V1C1,ATP6V1B2,ATP6V0D1,ATP6V0E1,ATP6V1G1 |
| 6.872e-03 | -4.98 | PCK1 (phosphoenolpyruvate carboxykinase 1) | protein interactions | 5105 | 75 | 21 | 17029 | 2761 |
CCT2,TSC22D3,MAGED1,PSMB7,LDHA,SIRT2,DNAJA1,APP,PSMC4,MAGED2,GNAS,CALM2,HLA-B,GNA12,PSMD2,NDUFA11,NUP62,ACTB,USP11,LPCAT1,PSMC1 |
| 6.872e-03 | -4.98 | RBBP5 (RB binding protein 5, histone lysine methyltransferase complex subunit) | protein interactions | 5929 | 75 | 21 | 17029 | 2761 |
CXXC1,WDR82,BRCA1,MEF2D,WDR5,MEN1,UBE2I,KMT2C,PAGR1,SRRT,CDC73,FERMT3,RB1,USF1,WAS,ZNF335,KMT2B,SMARCE1,DDB1,CDC5L,SMARCD1 |
| 6.872e-03 | -4.98 | RABGGTB (Rab geranylgeranyltransferase subunit beta) | protein interactions | 5876 | 75 | 21 | 17029 | 2761 |
RHOBTB3,NRAS,FOXK1,RAB7A,PRKAR1B,RAB6A,NOTCH2,RAB1A,BLM,BORA,RAB11A,GIT2,PIP5K1C,INPP5A,MCM5,WDR4,PTAR1,XRCC3,NCOA1,MCMBP,HRAS |
| 6.877e-03 | -4.98 | IPP (intracisternal A particle-promoted polypeptide) | protein interactions | 3652 | 12 | 6 | 17029 | 2761 |
RACGAP1,LANCL1,KLHL20,UBA5,CUL3,FERMT3 |
| 6.877e-03 | -4.98 | CAPN13 (calpain 13) | protein interactions | 92291 | 12 | 6 | 17029 | 2761 |
EWSR1,DIDO1,SAFB2,PRRC2A,SAFB,ATMIN |
| 6.877e-03 | -4.98 | ZSCAN31 (zinc finger and SCAN domain containing 31) | protein interactions | 64288 | 12 | 6 | 17029 | 2761 |
CDKN2AIP,PDCD11,MTMR4,DHX57,BBX,YTHDC2 |
| 6.877e-03 | -4.98 | HMCES (5-hydroxymethylcytosine binding, ES cell specific) | protein interactions | 56941 | 12 | 6 | 17029 | 2761 |
PLK1,RPA2,SKA3,HSPBP1,APP,NEIL3 |
| 6.877e-03 | -4.98 | ARHGDIG (Rho GDP dissociation inhibitor gamma) | protein interactions | 398 | 12 | 6 | 17029 | 2761 |
RHOG,PPIB,RHOA,CDC42,RHOB,RAC1 |
| 6.877e-03 | -4.98 | KDM6B (lysine demethylase 6B) | protein interactions | 23135 | 12 | 6 | 17029 | 2761 |
TK1,WAS,SMAD2,WDR5,SMAD1,SMAD4 |
| 6.877e-03 | -4.98 | Erp44 (endoplasmic reticulum protein 44) | protein interactions | 76299 | 12 | 6 | 17029 | 2761 |
FAM192A,SNRPG,AHNAK,MEN1,COPE,MRPL43 |
| 6.877e-03 | -4.98 | HOXC10 (homeobox C10) | protein interactions | 3226 | 12 | 6 | 17029 | 2761 |
CDC27,CWC27,MAPK14,TRMU,NUP205,SNX15 |
| 6.877e-03 | -4.98 | MT1G (metallothionein 1G) | protein interactions | 4495 | 12 | 6 | 17029 | 2761 |
RB1,E2F2,RBL1,E2F4,E2F1,E2F3 |
| 6.877e-03 | -4.98 | HOGA1 (4-hydroxy-2-oxoglutarate aldolase 1) | protein interactions | 112817 | 12 | 6 | 17029 | 2761 |
ADCK5,ABHD11,SPRYD4,LYRM4,ECH1,RCC1L |
| 6.877e-03 | -4.98 | ZNF354A (zinc finger protein 354A) | protein interactions | 6940 | 12 | 6 | 17029 | 2761 |
PPAN,DYNLL1,MECP2,TRIM28,ZC3HAV1,GPATCH4 |
| 6.877e-03 | -4.98 | RNASET2 (ribonuclease T2) | protein interactions | 8635 | 12 | 6 | 17029 | 2761 |
SUCLG2,ATP5IF1,NIT2,NDUFV1,PRDX3,MRPL12 |
| 6.877e-03 | -4.98 | JMY (junction mediating and regulatory protein, p53 cofactor) | protein interactions | 133746 | 12 | 6 | 17029 | 2761 |
MYH9,MDM2,E2F2,E2F4,E2F1,E2F3 |
| 6.877e-03 | -4.98 | CDH23 (cadherin related 23) | protein interactions | 64072 | 12 | 6 | 17029 | 2761 |
CYFIP1,NCKAP1,LYN,PPME1,GOPC,ABI1 |
| 6.877e-03 | -4.98 | CFDP1 (craniofacial development protein 1) | protein interactions | 10428 | 12 | 6 | 17029 | 2761 |
CSNK2A1,RBPJ,EWSR1,RUVBL2,TALDO1,APP |
| 6.877e-03 | -4.98 | RNU6ATAC (RNA, U6atac small nuclear (U12-dependent splicing)) | protein interactions | 100151684 | 12 | 6 | 17029 | 2761 |
USP39,SART1,PRPF4,SNRNP200,EFTUD2,DDX23 |
| 6.877e-03 | -4.98 | LRRTM2 (leucine rich repeat transmembrane neuronal 2) | protein interactions | 26045 | 12 | 6 | 17029 | 2761 |
TOMM40,CNPY3,PDE3B,DAD1,TYW1,CNPY4 |
| 6.877e-03 | -4.98 | RNU4ATAC (RNA, U4atac small nuclear (U12-dependent splicing)) | protein interactions | 100151683 | 12 | 6 | 17029 | 2761 |
USP39,SART1,PRPF4,SNRNP200,EFTUD2,DDX23 |
| 6.877e-03 | -4.98 | NOX5 (NADPH oxidase 5) | protein interactions | 79400 | 12 | 6 | 17029 | 2761 |
TTC4,HSPA4,UBE2I,GUCY1B1,PRKAR1B,DDRGK1 |
| 6.897e-03 | -4.98 | GSE29618_LAIV_VS_TIV_FLU_VACCINE_DAY7_MONOCYTE_UP | MSigDB lists | GSE29618_LAIV_VS_TIV_FLU_VACCINE_DAY7_MONOCYTE_UP | 180 | 40 | 17377 | 2626 |
CMAS,MRPL39,HNRNPUL2,CDCA8,STARD7,RPL15,ZFYVE21,GLUD1,FAM136A,SDHA,NFATC3,PTEN,DNAAF2,PRC1,CS,AHCY,GEMIN4,PCBP2,SMC4,CARS2,METTL1,DCAF6,CIC,KCTD20,SRSF5,TOMM40,PRPSAP1,PDE3B,SLC25A5,USP21,EPB41,MFAP1,RBMX,KHSRP,TAF12,GAS2,PITRM1,IGBP1,HIPK3,GPATCH4 |
| 6.897e-03 | -4.98 | GSE1112_OT1_VS_HY_CD8AB_THYMOCYTE_RTOC_CULTURE_UP | MSigDB lists | GSE1112_OT1_VS_HY_CD8AB_THYMOCYTE_RTOC_CULTURE_UP | 180 | 40 | 17377 | 2626 |
KIAA0100,TKT,PCSK7,AKT1S1,INO80E,AP1B1,PMVK,REEP5,CNOT3,EEF2K,IRF4,RAB8A,NDUFV1,INTS7,TTC9C,AKR1B1,MRPL48,ZC3H3,MLST8,RYBP,CDC37,SNX8,PPP1R9B,EMB,SLC26A6,TBRG4,PACS1,SRSF5,ECH1,PI4K2A,STOML2,UBTF,HLA-B,INF2,PALB2,MPV17,GPI,PIEZO1,UBE2C,PITRM1 |
| 6.897e-03 | -4.98 | GSE26669_CD4_VS_CD8_TCELL_IN_MLR_COSTIM_BLOCK_UP | MSigDB lists | GSE26669_CD4_VS_CD8_TCELL_IN_MLR_COSTIM_BLOCK_UP | 180 | 40 | 17377 | 2626 |
CYTIP,TMUB1,GOLPH3L,GMFG,KRBA1,MUM1,CCM2,SNN,SUPT7L,STMN1,CRLF3,BZW2,TMCC3,C14orf119,MRPL50,SEC11A,BDH1,AXIN2,CSNK1G3,SNX25,YTHDC1,PLK3,ACSL3,RFFL,GALK2,SOX4,GFER,PLEKHF2,RBM38,RPA1,PWWP2B,RBM47,CERS6,TFE3,ST3GAL2,SRSF3,MAP3K5,CDK2,E2F2,PDF |
| 6.897e-03 | -4.98 | GSE27241_CTRL_VS_DIGOXIN_TREATED_RORGT_KO_CD4_TCELL_IN_TH17_POLARIZING_CONDITIONS_UP | MSigDB lists | GSE27241_CTRL_VS_DIGOXIN_TREATED_RORGT_KO_CD4_TCELL_IN_TH17_POLARIZING_CONDITIONS_UP | 180 | 40 | 17377 | 2626 |
TCF12,TRIM41,WDR13,TCF3,KLF13,KIF23,RACGAP1,FAM8A1,CCDC28A,MIS12,PTPN2,FGFR3,RCSD1,PRC1,ARL6IP1,KNTC1,MYBL1,CELSR2,BTG2,LYRM1,CKAP2L,UHRF1BP1,ANLN,KIF11,ARSK,SLC25A5,RHEB,DDX23,VEZF1,MKNK1,KIF18B,MAFK,ARNTL,CAPN7,C4orf46,ANP32E,HMGB2,WDR76,TFDP2,GEN1 |
| 6.897e-03 | -4.98 | GSE17721_12H_VS_24H_GARDIQUIMOD_BMDC_DN | MSigDB lists | GSE17721_12H_VS_24H_GARDIQUIMOD_BMDC_DN | 180 | 40 | 17377 | 2626 |
SRM,POLA2,HSPH1,NDUFV2,TMED7,H2AFZ,PRKCSH,RPS6KA1,DAP,UROD,NIT2,MAPK14,STMN1,COPG2,SRXN1,CSDE1,RB1,NUP210,GATC,PTEN,CWC27,FBXW2,RPL19,EIF5,TMEM14C,KCNAB2,FAM49B,NOA1,TSPAN31,TUFM,TMEM216,VDAC1,PRKRA,MCFD2,TXNL4A,GINS4,SERF2,TULP3,NDUFA11,CLU |
| 6.897e-03 | -4.98 | GSE29164_DAY3_VS_DAY7_CD8_TCELL_TREATED_MELANOMA_DN | MSigDB lists | GSE29164_DAY3_VS_DAY7_CD8_TCELL_TREATED_MELANOMA_DN | 180 | 40 | 17377 | 2626 |
TMEM106C,CTDP1,ANKRD27,TP53RK,ANXA6,GPBP1L1,DHX8,ARFIP2,B4GALT4,UBE2I,NUP210,PPME1,ARF5,ATIC,RNASEK,DNM2,SNX8,PPIF,KDM3B,SRSF11,DCAF8,VHL,ARHGDIB,CADM1,TOMM40,TXNL4A,PSMB9,SYMPK,TRIM28,SNRPA,FADD,GIGYF1,CACNB1,SEPT1,TOMM6,E2F4,ATXN2L,KHSRP,PSAP,USP11 |
| 6.897e-03 | -4.98 | GSE17974_0H_VS_4H_IN_VITRO_ACT_CD4_TCELL_DN | MSigDB lists | GSE17974_0H_VS_4H_IN_VITRO_ACT_CD4_TCELL_DN | 180 | 40 | 17377 | 2626 |
SRM,CHMP2A,MMACHC,PIGM,CHAC2,FKBP2,S1PR2,COPB2,PNO1,C14orf119,LYAR,IRF4,TNS3,EIF2S2,GEMIN6,FTSJ3,SNX8,PPAN,JMJD4,POU2AF1,NASP,MRPL12,PSMG1,TMEM147,GAR1,FADD,PRDX1,MAGED2,ALG3,LTBP4,CCDC86,TTLL4,MFAP1,PSMD8,BAZ1B,MLYCD,RRS1,PDCD2L,IPO4,BYSL |
| 6.902e-03 | -4.98 | response to hydrogen peroxide | biological process | GO:0042542 | 105 | 26 | 17256 | 2622 |
PPIF,BAK1,TNFAIP3,NQO1,NET1,PPP1R15B,PRKAA1,LDHA,BECN1,ETS1,PARK7,RHOB,CAT,ANKZF1,PDCD10,PCNA,MDM2,KPNA4,PRDX3,STAT6,STAT1,ADAM9,BCL2,MAP3K5,PPP5C,HDAC2 |
| 6.926e-03 | -4.97 | GSE37605_C57BL6_VS_NOD_FOXP3_IRES_GFP_TCONV_DN | MSigDB lists | GSE37605_C57BL6_VS_NOD_FOXP3_IRES_GFP_TCONV_DN | 153 | 35 | 17377 | 2626 |
PRPF38B,GPR132,GMFG,KDM4A,DCAF15,FAM53C,ARID5A,USP39,S1PR2,GNS,HOMER1,SLC1A4,HDAC7,TTC9C,MRPL21,SCYL3,PACS2,CLPTM1,YTHDC1,ELL2,MAPKAPK3,TYW1,RNF25,EZR,RAB3IP,DNAJA1,LSG1,IRF5,AMZ2,SLC38A7,STK38,LUC7L3,CRCP,TCOF1,PPP2R2D |
| 6.926e-03 | -4.97 | ACCATTT,MIR-522 | MSigDB lists | ACCATTT,MIR-522 | 153 | 35 | 17377 | 2626 |
CDS2,EWSR1,IVNS1ABP,ARID2,MECP2,WDTC1,CBLL1,CUL1,KIF23,PRPF39,CSNK1A1,MYEF2,CSDE1,UBE2Q2,IMPAD1,PTPN11,TNPO2,JOSD1,HNRNPM,SLC39A9,APH1A,EHMT1,TOPORS,RTF1,KRAS,MEF2D,EIF2A,EIF4H,AKAP1,SH3BP5,TMEM168,SYNCRIP,RBMX,YWHAZ,ZRANB2 |
| 6.929e-03 | -4.97 | RABGAP1 (RAB GTPase activating protein 1) | protein interactions | 23637 | 35 | 12 | 17029 | 2761 |
KIF5B,GGA1,RABGAP1L,TRIM11,COPE,RAB4A,CORO1A,RAB6A,WIPI2,STAT3,SENP1,CARM1 |
| 6.929e-03 | -4.97 | CLASRP (CLK4 associating serine/arginine rich protein) | protein interactions | 11129 | 35 | 12 | 17029 | 2761 |
WSB2,TMEM184B,ATXN1,CFAP20,DAZAP2,LUC7L,PIP4K2A,APP,LUC7L2,RBM38,TERF2,SRPK2 |
| 6.929e-03 | -4.97 | NIPBL (NIPBL, cohesin loading factor) | protein interactions | 25836 | 35 | 12 | 17029 | 2761 |
RPA2,EWSR1,SMC3,SP100,PPT1,BRCA1,TOMM40,TFG,SF3A2,RPA1,CDC5L,CBX3 |
| 6.929e-03 | -4.97 | ETV6 (ETS variant 6) | protein interactions | 2120 | 35 | 12 | 17029 | 2761 |
CRKL,USP7,FBXL6,VPS26B,WDYHV1,PIN1,ETV6,AP1M1,NFATC2,LRP5,UBE2I,SMURF1 |
| 6.929e-03 | -4.97 | CIITA (class II major histocompatibility complex transactivator) | protein interactions | 4261 | 35 | 12 | 17029 | 2761 |
PML,RFXANK,CUL3,SMARCA4,ACTB,NCOA1,PRKACA,MAPK1,TAF6,HDAC2,POLR2A,MAPK3 |
| 6.929e-03 | -4.97 | RBM5 (RNA binding motif protein 5) | protein interactions | 10181 | 35 | 12 | 17029 | 2761 |
RBM17,FGFR1OP,SNRNP200,SUZ12,U2SURP,ILF3,LSM8,XRCC3,BCL2L1,SF3A2,DHX15,PRPF19 |
| 6.929e-03 | -4.97 | TROVE2 (TROVE domain family member 2) | protein interactions | 6738 | 35 | 12 | 17029 | 2761 |
UNK,SUB1,GART,HSPA4,UGP2,PPM1G,CUL3,JMJD6,RBM3,XPO7,PAGR1,FAF1 |
| 6.929e-03 | -4.97 | PHF5A (PHD finger protein 5A) | protein interactions | 84844 | 35 | 12 | 17029 | 2761 |
RBM25,SUZ12,SF3B1,SUMO2,SF3B6,DHX8,YBX1,PPP3CB,MCM2,SF3A2,DDX23,SF3B2 |
| 6.929e-03 | -4.97 | OLFM4 (olfactomedin 4) | protein interactions | 10562 | 35 | 12 | 17029 | 2761 |
MTFR1L,ETV3,ERF,FAAP100,TOR3A,FUT8,WDR59,DHFR2,SDF2L1,APP,DNAJB9,PDF |
| 6.929e-03 | -4.97 | ZNF764 (zinc finger protein 764) | protein interactions | 92595 | 35 | 12 | 17029 | 2761 |
PPP2CA,TRIM41,MDM2,TRAF7,SNX18,ZNF316,RPS27A,GNE,KRAS,ERBIN,TRIM28,USP34 |
| 6.929e-03 | -4.97 | GLOD4 (glyoxalase domain containing 4) | protein interactions | 51031 | 35 | 12 | 17029 | 2761 |
PDCD6IP,TXN,TKT,WDR82,GLO1,NANS,BCL2L1,FKBP2,TALDO1,PCBP1,SDHA,APP |
| 6.929e-03 | -4.97 | TAGLN3 (transgelin 3) | protein interactions | 29114 | 35 | 12 | 17029 | 2761 |
FKBP1A,HSPH1,CLIC4,HSPA4,TXN,HINT1,PIN1,DUT,UBXN1,TKT,TAGLN2,NUTF2 |
| 6.929e-03 | -4.97 | FAM129B (family with sequence similarity 129 member B) | protein interactions | 64855 | 35 | 12 | 17029 | 2761 |
KEAP1,SNX2,CORO1C,KRAS,PAWR,H3F3A,HRAS,TARS,VPS29,CDC5L,PAPOLA,NUDC |
| 6.929e-03 | -4.97 | NVL (nuclear VCP-like) | protein interactions | 4931 | 35 | 12 | 17029 | 2761 |
PPAN,RHOA,DGCR8,ZNF512,RBM34,MECP2,CUL3,UBE2I,MAK16,RBM4,GPATCH4,IFI16 |
| 6.929e-03 | -4.97 | CFAP97 (cilia and flagella associated protein 97) | protein interactions | 57587 | 35 | 12 | 17029 | 2761 |
INF2,CDC16,PCM1,CDC27,CSNK2A1,HMGB2,ANAPC7,BEND3,CDC23,ANAPC4,CDKN2A,DCTN1 |
| 6.930e-03 | -4.97 | AACTGGA,MIR-145 | MSigDB lists | AACTGGA,MIR-145 | 213 | 46 | 17377 | 2626 |
RAB14,SNX27,ZBTB10,SCAMP3,MTX3,TM9SF4,IVNS1ABP,PHRF1,ACTR3,PLAGL2,UBE2Z,CHKB,ADPGK,AP3S1,RTKN,ANKRD28,ASAP2,ADD3,ARPC5,DPYSL2,MDFIC,TAGLN2,MRPL48,PLCL2,CITED2,NSUN4,MYO5A,VPS13B,YTHDC1,PPP3CA,BAZ2A,NET1,ERLIN1,NUDT4,MAP4K4,CBFB,FKBP3,NAP1L1,FBXO28,ELMO1,GOLGA8A,H2AFX,TBPL1,ACTB,ABCA1,PDCD4 |
| 6.933e-03 | -4.97 | WHITFIELD_CELL_CYCLE_M_G1 | MSigDB lists | WHITFIELD_CELL_CYCLE_M_G1 | 137 | 32 | 17377 | 2626 |
UBE2D3,PTMS,MRPS2,FOPNL,PBK,DYNLL1,NUDT4,AMD1,PTTG1,AGPAT3,KRAS,AGFG1,FXR1,PSEN1,MRPL19,RHEB,CBX3,PPP2CA,LYAR,KIF5B,SNUPN,SYNCRIP,CDC42,ODF2,PRC1,CTR9,DCP1A,ANP32E,SRSF3,PPP6R3,YY1,MTPN |
| 6.944e-03 | -4.97 | GSE39820_CTRL_VS_TGFBETA1_IL6_CD4_TCELL_DN | MSigDB lists | GSE39820_CTRL_VS_TGFBETA1_IL6_CD4_TCELL_DN | 191 | 42 | 17377 | 2626 |
CCNC,GALK1,ZNF496,FEZ2,CORO7,CDS2,MAPRE1,UGP2,CAST,TMX4,HEXB,ACAP1,B4GALT1,DAZAP2,RAB11A,RGS1,SIAH1,PPME1,TBC1D14,ETV6,CAPZA1,YIF1B,ABI1,TMEM14C,DRAM2,ZDHHC18,EID1,IL12RB1,EAF2,PICALM,PLEKHF2,NECAP2,YIF1A,ATP6V1D,CCDC6,PSMD8,STX18,PSAP,XRCC4,LONP2,ATP6V0E1,TSPAN5 |
| 6.944e-03 | -4.97 | GSE29618_BCELL_VS_MDC_DN | MSigDB lists | GSE29618_BCELL_VS_MDC_DN | 191 | 42 | 17377 | 2626 |
RHOG,TXN,GMFG,CKLF,FAM129A,NDUFA4,RGS1,LMNA,SSR1,DST,FKBP1A,SEC11A,ARPC5,DPYSL2,ATG3,GRSF1,RRBP1,H2AFY,ANXA5,CORO1A,GNAI2,TIPARP,S100A6,IMPA2,PPIF,CYFIP1,RAB7A,SELPLG,WDR1,CAPZA2,PTTG1IP,PICALM,CAT,ETS2,DDOST,DUSP3,COX8A,LY75,ACTB,RBPJ,TOB1,NUDT3 |
| 6.944e-03 | -4.97 | GSE41867_LCMV_ARMSTRONG_VS_CLONE13_DAY15_EFFECTOR_CD8_TCELL_UP | MSigDB lists | GSE41867_LCMV_ARMSTRONG_VS_CLONE13_DAY15_EFFECTOR_CD8_TCELL_UP | 191 | 42 | 17377 | 2626 |
KCTD7,COMMD10,IER2,CORO7,TXN,GMFG,AGRN,ZCCHC8,SNN,CRLF3,BIRC2,MAN1A1,EDC3,UBLCP1,MRPS27,CS,PARL,NDUFB9,TAP2,CYB5R1,FBXL19,ZNRD1,MRPL32,SPSB3,ABCC1,TSHZ1,CCT2,CYFIP1,SHOC2,ORAI2,TMEM39A,USP42,FAM133B,ARID1A,VDAC1,ANKZF1,TRAM2,MEGF9,NUP62,GPI,MAP3K5,PDF |
| 6.944e-03 | -4.97 | GSE7852_TREG_VS_TCONV_UP | MSigDB lists | GSE7852_TREG_VS_TCONV_UP | 191 | 42 | 17377 | 2626 |
LYRM4,H2AFZ,TMBIM4,FAM129A,CERK,PLAGL2,NKRF,LCLAT1,REPS1,TFRC,RGS1,EEF2K,PRNP,ITGB8,VMP1,TANK,MDFIC,CLDND1,LMAN1,MGAT5,ARL5A,TRIM14,ABCC1,SOCS5,EIF5A,ERMP1,HEMK1,BIRC3,POLK,MAPKAPK3,TSPAN31,CYP20A1,ZBED5,UHRF1BP1,PRKRA,MAGED2,MTMR3,ZNF862,INF2,ZC3H7B,ST3GAL2,CD81 |
| 6.944e-03 | -4.97 | GSE25088_IL4_VS_IL4_AND_ROSIGLITAZONE_STIM_MACROPHAGE_DAY10_UP | MSigDB lists | GSE25088_IL4_VS_IL4_AND_ROSIGLITAZONE_STIM_MACROPHAGE_DAY10_UP | 191 | 42 | 17377 | 2626 |
SKA3,PDCD6IP,VAV2,TMEM109,FAM76A,DNAJC24,UBE2Z,CTCF,TOP2B,KIF2C,ARF1,ASXL2,ITGB5,MYEF2,ARL6IP6,KIFC1,CAPN2,CLUAP1,SUB1,NOL11,GLIS2,MBD2,SLC44A1,ZDHHC13,MTPN,CPNE1,ANKLE2,NEK7,CRNKL1,ARID1A,ELK1,EIF4G2,SH3BP5,RAD51C,RBM47,TXNDC16,TMED10,RBMX,CTBS,RBPJ,E2F2,HRAS |
| 6.944e-03 | -4.97 | GSE7831_UNSTIM_VS_CPG_STIM_PDC_1H_DN | MSigDB lists | GSE7831_UNSTIM_VS_CPG_STIM_PDC_1H_DN | 191 | 42 | 17377 | 2626 |
KIF3B,PLXNC1,KIAA0100,GNPNAT1,ARID5A,ZNRF3,COPG2,RGS1,MAN1A1,PRNP,RBM17,CAPN2,FKBP1A,ATP6V0B,RABGAP1L,MBD2,FUT8,TP53BP2,PTPRK,TGFB1,CDKN2AIP,DCAF6,TCTEX1D2,SEPT9,LYRM1,MRS2,MIER1,FRAT2,ABHD11,FAM133B,USP22,EDEM2,POLG2,GFER,PHF6,FBXO28,TMED10,HIPK2,TMEM159,DNAJC30,XRCC4,RAD51D |
| 6.960e-03 | -4.97 | COMM | prosite domains | PS51269 | 10 | 5 | 12060 | 1670 |
COMMD10,COMMD5,COMMD4,COMMD6,COMMD8 |
| 6.963e-03 | -4.97 | genital_tract-extragonadal-germ_cell_tumour | COSMIC cancer mutations | genital_tract-extragonadal-germ_cell_tumour | 29 | 10 | 17385 | 2587 |
GNAS,DNMT3A,NRAS,PTEN,SF3B1,PTPN11,KRAS,HRAS,CDKN2A,PHF6 |
| 6.965e-03 | -4.97 | AMBRA1 (autophagy and beclin 1 regulator 1) | protein interactions | 55626 | 94 | 25 | 17029 | 2761 |
WSB2,UBE2D3,COPS8,CCT2,WDR1,DYNLL1,PSMA1,DNAJB1,BECN1,CCT8,PSMB3,PSMC4,PPP2CA,PSMD2,PSMA6,TBC1D22A,ATG3,PSMD8,PSMD3,DDA1,CAMKMT,BCL2,ATG13,PSMC1,DDB1 |
| 6.973e-03 | -4.97 | GO_POSITIVE_REGULATION_OF_CANONICAL_WNT_SIGNALING_PATHWAY | MSigDB lists | GO_POSITIVE_REGULATION_OF_CANONICAL_WNT_SIGNALING_PATHWAY | 116 | 28 | 17377 | 2626 |
ZBED3,PSMA8,ASPM,PSMB7,XIAP,PSMA1,SOX4,PSMB9,PSMD9,PSMB3,DAPK3,PSMC4,PSMD2,PSMA6,PSMD1,RPS27A,PSMD8,PSMD3,PIN1,AXIN1,ARNTL,AXIN2,RBPJ,DVL1,PSMC1,CSNK1D,DVL2,USP34 |
| 6.991e-03 | -4.96 | G_PATCH | prosite domains | PS50174 | 22 | 8 | 12060 | 1670 |
RBM17,SUGP1,AGGF1,CHERP,SUGP2,GPATCH1,NKRF,GPATCH4 |
| 6.991e-03 | -4.96 | PWWP | prosite domains | PS50812 | 22 | 8 | 12060 | 1670 |
PWWP2A,NSD3,PWWP2B,DNMT3A,HDGFL2,BRPF3,ZMYND11,MSH6 |
| 7.005e-03 | -4.96 | Bacterial invasion of epithelial cells | KEGG pathways | ko05100 | 76 | 21 | 7161 | 1149 |
WASF2,RHOG,RHOA,SEPT9,RAC1,SEPT8,ARPC1A,MAD2L2,CRKL,WAS,SEPT1,SHC1,CDC42,ARPC5,ELMO1,PIK3R2,DNM2,ITGB1,SEPT11,ACTB,CLTB |
| 7.005e-03 | -4.96 | Bacterial invasion of epithelial cells | KEGG pathways | hsa05100 | 76 | 21 | 7161 | 1149 |
WASF2,RHOG,RHOA,SEPT9,RAC1,SEPT8,ARPC1A,MAD2L2,CRKL,WAS,SEPT1,SHC1,CDC42,ARPC5,ELMO1,PIK3R2,DNM2,ITGB1,SEPT11,ACTB,CLTB |
| 7.024e-03 | -4.96 | regulation of protein acetylation | biological process | GO:1901983 | 70 | 19 | 17256 | 2622 |
TGFB1,KAT2A,EID1,KAT7,MECP2,PRKAA1,WBP2,BRCA1,SOX4,PARK7,MAPK3,IWS1,TERF2IP,ARNTL,NOC2L,BRD7,RUVBL2,SMAD4,HDAC2 |
| 7.029e-03 | -4.96 | RNA polymerase II transcription factor complex | cellular component | GO:0090575 | 156 | 35 | 18223 | 2701 |
RORB,TCF12,MAX,HNRNPAB,TCF3,TAF6L,GTF2F1,RB1,MED8,MED10,TAF5L,TCEA1,CREB1,STAT3,GTF2H2,CARM1,POU2AF1,ERCC1,KAT2A,LDB1,E2F3,EDF1,PRMT2,TRIM28,TAF2,SMAD2,HIPK2,TFDP1,TBPL1,E2F1,TAF12,TFDP2,TAF6,E2F2,SMAD4 |
| 7.056e-03 | -4.95 | RNA Polymerase II Pre-transcription Events | REACTOME pathways | R-HSA-674695 | 88 | 24 | 10287 | 1696 |
CTDP1,POLR2I,POLR2G,POLR2L,POLR2K,ELOA,POLR2D,RTF1,EAF2,CDC73,POLR2A,GTF2F1,IWS1,SUPT16H,TAF2,CCNK,PAF1,POLR2J,CTR9,TCEA1,TAF12,TAF6,GTF2H2,SSRP1 |
| 7.066e-03 | -4.95 | regulation of multi-organism process | biological process | GO:0043900 | 393 | 78 | 17256 | 2622 |
CHMP2A,TRIM11,YTHDC2,SMARCA4,IRF3,SIRT2,CHD1,BIRC2,ELMOD2,RAD23A,ZNF639,TARDBP,MAVS,RNF26,FAM3A,TRIM14,CFL1,PCBP2,SRPK2,TRIM8,BIRC3,POLR2L,POLR2G,CGAS,RAB7A,INTS13,PPIE,POLR2D,ARHGDIB,IL12RB1,CHMP2B,TRIM28,OPTN,PQBP1,STAT1,CHMP4B,RNASEL,TRIM32,VPS4A,DDX58,MIF,PPIB,CTDP1,POLR2K,AGO2,DHX9,CIB1,B4GALT1,EIF2AK4,RHBDD1,NPLOC4,GTF2F1,TMEM250,CCNK,TFAP4,SMC3,BANF1,BCL2,MDFIC,LRSAM1,PABPC1,STAU1,POLR2I,TNFAIP3,ILF3,ZP3,POLR2A,ISG15,MAPK3,SCARB2,TRIM26,POLR2J,PML,DDX5,PARP10,DDB1,ZC3HAV1,IFI16 |
| 7.071e-03 | -4.95 | FBXL7 down-regulates AURKA during mitotic entry and in early mitosis | REACTOME pathways | R-HSA-8854050 | 56 | 17 | 10287 | 1696 |
PSMA8,RBX1,PSMB7,PSMA1,CUL1,PSMB9,PSMD9,PSMB3,PSMC4,PSMD2,PSMA6,PSMD1,RPS27A,PSMD3,PSMD8,FBXL7,PSMC1 |
| 7.076e-03 | -4.95 | uropod | cellular component | GO:0001931 | 13 | 6 | 18223 | 2701 |
MYH9,EZR,ICAM2,SELPLG,PIP5K1C,FLOT1 |
| 7.076e-03 | -4.95 | Prp19 complex | cellular component | GO:0000974 | 13 | 6 | 18223 | 2701 |
CTNNBL1,XAB2,POLR2A,CRNKL1,PRPF19,CDC5L |
| 7.076e-03 | -4.95 | cell trailing edge | cellular component | GO:0031254 | 13 | 6 | 18223 | 2701 |
MYH9,EZR,ICAM2,SELPLG,PIP5K1C,FLOT1 |
| 7.076e-03 | -4.95 | SMN complex | cellular component | GO:0032797 | 13 | 6 | 18223 | 2701 |
GEMIN6,GEMIN5,DDX20,GEMIN4,STRAP,GEMIN7 |
| 7.105e-03 | -4.95 | Thioredoxin | pfam domains | PF00085 | 29 | 10 | 17054 | 2545 |
TXNL1,DNAJC10,TXN,TXNDC16,PDIA6,GLRX3,QSOX2,TMX4,TMX1,TMX3 |
| 7.110e-03 | -4.95 | GO_NEGATIVE_REGULATION_OF_CATALYTIC_ACTIVITY | MSigDB lists | GO_NEGATIVE_REGULATION_OF_CATALYTIC_ACTIVITY | 793 | 145 | 17377 | 2626 |
FGFR1OP,TSC2,UBN1,NF1,XIAP,ENSA,CSNK2A1,CCNB1,BIRC2,PARK7,CDKN2C,PSMD1,CRY2,PLK1,NCK1,AKT2,GMFB,LRP5,PRPSAP1,HHEX,RPS27A,PSMD8,LIMK1,PRDX5,SOCS4,ROCK1,DVL1,CLN3,ARRB2,PSMC1,POT1,OAZ1,PDCD4,ZCCHC9,GMFG,PPP1R12A,PPP1R2,UBXN1,CIB1,RGS2,PSEN1,PSMD9,RTKN,TFAP4,FKBP1A,RB1,FBXO7,ARL6IP1,PIK3IP1,MVP,GNAI2,TMED2,TERF2,SOCS5,GBA,PSMA1,PSMB3,PSMC4,MASTL,CAND1,MBIP,HSPBP1,CDC27,DUSP3,CSK,SIAH2,NUP62,CABIN1,GPI,CDK2,CDKN2A,EGLN1,PPP1R37,NQO1,RAF1,RPS6KA1,CAST,PTTG1,WDTC1,LYN,DUSP22,APP,APLP2,PSMA6,MDM2,TNFAIP8,UCHL5,PPME1,SOCS6,CDKN1B,ANAPC7,PPIF,TIMP2,BIRC3,CUL3,PSMB7,PKMYT1,DNAJA1,CDC23,PSMB9,SOCS7,PPP2CA,CDC16,PPP2R5A,HNRNPR,CORO1C,PSMD3,STK38,GADD45B,ANP32E,BCL2L12,AKT1S1,MAD2L2,FBXO5,PTPN2,PSMD2,PTEN,PPP1R8,ANXA5,H2AFY,PDPK1,PPP1R9B,TNFAIP3,PRKAR1B,RFFL,ANAPC2,WDR81,MEN1,PICALM,SH3BP5,PRDX3,GPS2,BIRC5,OAZ2,PML,PPP1R11,NR2F2,UBE2C,IGBP1,CPEB2,HIPK3,TERF1,HRAS,IFI16,ANAPC4 |
| 7.117e-03 | -4.95 | GNF2_CD48 | MSigDB lists | GNF2_CD48 | 33 | 11 | 17377 | 2626 |
VAV1,HLA-B,CORO7,TNFAIP8,CSK,HLA-E,STAT6,MBD2,ARHGDIB,CORO1A,HLA-A |
| 7.117e-03 | -4.95 | PID_EPO_PATHWAY | MSigDB lists | PID_EPO_PATHWAY | 33 | 11 | 17377 | 2626 |
CRKL,RAP1A,SHC1,VAV2,STAT1,PTPN11,BCL2,BCL2L1,MAPK14,LYN,HRAS |
| 7.117e-03 | -4.95 | LUI_TARGETS_OF_PAX8_PPARG_FUSION | MSigDB lists | LUI_TARGETS_OF_PAX8_PPARG_FUSION | 33 | 11 | 17377 | 2626 |
EIF3K,RPS2,HINT1,RPL17,ERGIC3,DNAJA1,TMEM147,SRSF3,FBL,ODC1,EIF3G |
| 7.117e-03 | -4.95 | ZHAN_LATE_DIFFERENTIATION_GENES_UP | MSigDB lists | ZHAN_LATE_DIFFERENTIATION_GENES_UP | 33 | 11 | 17377 | 2626 |
CAPN2,PPT1,SELPLG,HEXB,ACAT1,EMP3,BCL2,MCFD2,ARPC1A,S100A6,RHEB |
| 7.117e-03 | -4.95 | GO_RNA_CAPPING | MSigDB lists | GO_RNA_CAPPING | 33 | 11 | 17377 | 2626 |
METTL1,POLR2I,POLR2J,POLR2G,POLR2L,POLR2K,WDR4,POLR2D,GTF2H2,POLR2A,GTF2F1 |
| 7.117e-03 | -4.95 | GO_POSITIVE_REGULATION_OF_CYTOKINESIS | MSigDB lists | GO_POSITIVE_REGULATION_OF_CYTOKINESIS | 33 | 11 | 17377 | 2626 |
KIF3B,PKP4,RHOA,CDC42,KIF14,CUL3,KIF23,CDC6,RACGAP1,CDC25B,AURKB |
| 7.117e-03 | -4.95 | GO_7_METHYLGUANOSINE_RNA_CAPPING | MSigDB lists | GO_7_METHYLGUANOSINE_RNA_CAPPING | 33 | 11 | 17377 | 2626 |
METTL1,POLR2I,POLR2J,POLR2G,POLR2L,POLR2K,WDR4,POLR2D,GTF2H2,POLR2A,GTF2F1 |
| 7.117e-03 | -4.95 | GO_REGULATION_OF_ALTERNATIVE_MRNA_SPLICING_VIA_SPLICEOSOME | MSigDB lists | GO_REGULATION_OF_ALTERNATIVE_MRNA_SPLICING_VIA_SPLICEOSOME | 33 | 11 | 17377 | 2626 |
RBM25,NSRP1,RBMX,SRSF6,RBM8A,RNPS1,TRA2B,DDX5,THRAP3,RBM4,RBM15B |
| 7.117e-03 | -4.95 | REACTOME_MRNA_3_END_PROCESSING | MSigDB lists | REACTOME_MRNA_3_END_PROCESSING | 33 | 11 | 17377 | 2626 |
SRSF11,CDC40,SRSF6,SRSF4,RBM8A,RNPS1,SRSF5,SRSF3,SRSF1,CSTF1,PAPOLA |
| 7.117e-03 | -4.95 | GO_REGULATION_OF_PROTEIN_EXPORT_FROM_NUCLEUS | MSigDB lists | GO_REGULATION_OF_PROTEIN_EXPORT_FROM_NUCLEUS | 33 | 11 | 17377 | 2626 |
CDK5,MDM2,TXN,SP100,PTPN11,GTSE1,RANGAP1,SOX4,PRKACA,PARK7,CDKN2A |
| 7.117e-03 | -4.95 | GCM_BAG5 | MSigDB lists | GCM_BAG5 | 33 | 11 | 17377 | 2626 |
SAP130,RAB14,NAPG,TAB2,SETD3,XIAP,STARD7,YTHDF3,FN3KRP,FBXO9,UBQLN2 |
| 7.124e-03 | -4.94 | SLC7A6OS (solute carrier family 7 member 6 opposite strand) | protein interactions | 84138 | 23 | 9 | 17029 | 2761 |
SNRNP200,SNRPB,EFTUD2,RUVBL2,ECD,SNRPG,SNRPD3,WDR5,PRPF19 |
| 7.124e-03 | -4.94 | BUD13 (BUD13 homolog) | protein interactions | 84811 | 23 | 9 | 17029 | 2761 |
NOL12,NIFK,ZNF512,RPS14,NABP2,KIFAP3,RBM4,GPATCH4,SRPK2 |
| 7.124e-03 | -4.94 | GLE1 (GLE1, RNA export mediator) | protein interactions | 2733 | 23 | 9 | 17029 | 2761 |
IER2,MEX3C,NUP107,NUP153,NUP155,GLE1,RRS1,IFI16,SEH1L |
| 7.124e-03 | -4.94 | SPIN2B (spindlin family member 2B) | protein interactions | 474343 | 23 | 9 | 17029 | 2761 |
SPINDOC,PFDN4,WDHD1,TOPORS,WDR76,MCM2,CGGBP1,SUPT16H,SSRP1 |
| 7.124e-03 | -4.94 | LYPLA2 (lysophospholipase II) | protein interactions | 11313 | 23 | 9 | 17029 | 2761 |
UFC1,TKT,LACTB2,MCM2,PKM,SPR,APP,CFL1,MLST8 |
| 7.124e-03 | -4.94 | PLP1 (proteolipid protein 1) | protein interactions | 5354 | 23 | 9 | 17029 | 2761 |
NRAS,STRIP1,STRN4,SIKE1,ITGB5,REEP5,LMNA,FGFR1OP2,RNF114 |
| 7.124e-03 | -4.94 | SCNN1A (sodium channel epithelial 1 alpha subunit) | protein interactions | 6337 | 23 | 9 | 17029 | 2761 |
DERL1,HGS,HUWE1,CSNK2A1,USP10,EPN1,UBE2I,SERP1,WWP2 |
| 7.124e-03 | -4.94 | LRRC1 (leucine rich repeat containing 1) | protein interactions | 55227 | 23 | 9 | 17029 | 2761 |
RBM23,MAPRE2,CLK3,ERBIN,GAR1,CNPY3,MAPK14,APP,CDC5L |
| 7.124e-03 | -4.94 | PHF7 (PHD finger protein 7) | protein interactions | 51533 | 23 | 9 | 17029 | 2761 |
USP7,TRIM41,MDM2,TRIM26,IDE,PPP1R12A,KRAS,RNF14,APP |
| 7.124e-03 | -4.94 | TPBG (trophoblast glycoprotein) | protein interactions | 7162 | 23 | 9 | 17029 | 2761 |
SRSF11,SAFB,SF3B6,BUD31,SMU1,USP39,SEPT7,CDC5L,HP1BP3 |
| 7.124e-03 | -4.94 | SCAF1 (SR-related CTD associated factor 1) | protein interactions | 58506 | 23 | 9 | 17029 | 2761 |
UBQLN4,NIFK,POLR2G,THOC1,JMJD6,SNRNP70,NKAPD1,RBM4,SRPK2 |
| 7.124e-03 | -4.94 | ASB18 (ankyrin repeat and SOCS box containing 18) | protein interactions | 401036 | 23 | 9 | 17029 | 2761 |
ERH,SRSF6,AKR1B1,RPL15,BCLAF1,THRAP3,TFG,PRPSAP1,SLC25A5 |
| 7.124e-03 | -4.94 | CRIP2 (cysteine rich protein 2) | protein interactions | 1397 | 23 | 9 | 17029 | 2761 |
TK1,SARNP,KLF10,PPT1,GADD45G,AEN,ATXN1,PCYT2,APP |
| 7.124e-03 | -4.94 | NKTR (natural killer cell triggering receptor) | protein interactions | 4820 | 23 | 9 | 17029 | 2761 |
WSB2,ZNF786,APLP2,RPS14,RNPS1,NKAPD1,MAPK14,LUC7L,ARRB2 |
| 7.126e-03 | -4.94 | negative regulation of nucleic acid-templated transcription | biological process | GO:1903507 | 1214 | 215 | 17256 | 2622 |
RORB,TXN,ZNF496,MAX,H2AFZ,KDM4A,TSC22D3,TRIM11,SIRT2,UBE2I,CREM,CDK5,PA2G4,CIPC,GLIS2,ZNF639,JAZF1,ETV6,NOC2L,CRY2,FNIP2,SMARCE1,DNMT1,ARID4A,CCAR1,RYBP,PTPRK,PLK1,PLK3,SP3,DEAF1,KLF10,PBXIP1,NCK1,BAZ2A,GABPA,VHL,EHMT1,RIOX2,EZR,DDX20,AURKB,BRCA1,DOT1L,PAF1,BRMS1,HHEX,SMAD2,TONSL,RPS27A,RPS14,AXIN1,PRDX5,ZNF268,TFDP2,BEND6,HDAC2,PDCD4,ZNF564,UBE2D3,PHB2,CENPF,CTCF,MEF2A,DNAJB1,PSEN1,CDC73,LYAR,TFAP4,RB1,MLX,NFATC3,KLF16,MBD2,HDAC7,ZNF746,PHF14,CTR9,TIMELESS,MDFIC,YBX1,MCPH1,TNRC18,ZNF189,ETV3,FOXK1,CREG1,ZMYND11,CIC,MTA2,LDB1,BCLAF1,RTF1,ARID1A,CBFA2T2,ZNF174,PHF6,XRCC5,PFDN5,ETS2,QARS,NFIL3,SIAH2,ZFP90,RUVBL2,YY1,CDK2,TOB1,N4BP2L2,CDKN2A,MBD1,ZNF296,DNMT3A,MPHOSPH8,FOXM1,SUZ12,UBR2,MAGED1,WDTC1,SMARCA4,IRF3,DUSP22,RCOR3,MXD1,HNRNPA2B1,SPINDOC,SAP130,ZBTB21,MDM2,SHC1,SP100,MTA1,CDKN1B,ATF2,RBM15,STRAP,CGGBP1,RLIM,MOSPD1,SAP30,FAM172A,ZNF500,ERF,EID1,BTG2,DRAP1,PCGF6,CUL3,ATXN1,NFATC2,H2AFV,MBD3,TRIM28,CHCHD3,ZNF282,RBL1,MAFK,HIPK2,STAT6,ARNTL,H2AFX,DNAJC17,STAT1,BEND3,H3F3A,SMAD4,LRP8,CBX4,NCOR2,DEPDC1,DAP,MECP2,TCF3,ARID5A,PAWR,NKRF,MXD4,FOXO3,HMG20A,MAD2L2,WWP2,PTPN2,SUV39H2,KMT5A,H2AFY,BRD7,CITED2,CREB1,STAT3,NCOA2,RBM15B,TSHZ1,TGFB1,PSPC1,ZNF202,BTAF1,ILF3,RCOR1,PRMT2,MEN1,ZP3,CBX3,BIRC5,GPS2,ZHX1,PITX1,E2F1,PML,HMGB2,DDX5,RBPJ,NR2F2,IGBP1,PURA,IFI16 |
| 7.128e-03 | -4.94 | positive regulation of mitotic cell cycle phase transition | biological process | GO:1901992 | 75 | 20 | 17256 | 2622 |
TGFB1,UBE2E2,BRD4,KMT2E,PHB2,MECP2,CDT1,CUL3,CDC6,CCNB1,RAB11A,APP,DTL,RB1,RAD51C,MDM2,NSMCE2,CDCA5,UBE2C,ESPL1 |
| 7.128e-03 | -4.94 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent | biological process | GO:0002479 | 75 | 20 | 17256 | 2622 |
PSMA8,HLA-E,TAP1,PSMB7,PSMA1,ITGB5,PSMB9,PSMD9,PSMB3,HLA-A,PSMC4,HLA-B,PSMD2,PSMD1,PSMA6,PSMD8,SNAP23,PSMD3,TAP2,PSMC1 |
| 7.131e-03 | -4.94 | p53-Dependent G1/S DNA damage checkpoint | REACTOME pathways | R-HSA-69580 | 65 | 19 | 10287 | 1696 |
PSMA8,PSMB7,PSMA1,PSMB9,PSMD9,PSMB3,PSMC4,PSMD2,PSMA6,CCNA2,PSMD1,MDM2,RPS27A,PSMD3,PSMD8,CDKN1B,CHEK2,CDK2,PSMC1 |
| 7.131e-03 | -4.94 | p53-Dependent G1 DNA Damage Response | REACTOME pathways | R-HSA-69563 | 65 | 19 | 10287 | 1696 |
PSMA8,PSMB7,PSMA1,PSMB9,PSMD9,PSMB3,PSMC4,PSMD2,PSMA6,CCNA2,PSMD1,MDM2,RPS27A,PSMD3,PSMD8,CDKN1B,CHEK2,CDK2,PSMC1 |
| 7.141e-03 | -4.94 | V$MYB_Q3 | MSigDB lists | V$MYB_Q3 | 230 | 49 | 17377 | 2626 |
PTMS,PRPF38B,PLXNC1,GMFG,SF3B1,PDAP1,TOR1AIP1,CDCA3,TMEM97,SECISBP2,RGS2,LYN,MYL6B,LMNA,USP5,ANKRD28,CSDE1,VAV1,NRF1,TNPO3,ZNF800,PREB,CSTF1,ABHD2,RHOBTB3,EHMT1,HNRNPF,WDR81,CADM1,SRSF5,HERPUD2,EPB41,RDH11,GNAS,ANKZF1,HHEX,AHNAK,GOLGA7,ORMDL2,ZNF367,LUC7L3,ODF2,MAP4,OAZ2,USP32,VCPIP1,MBD6,CDK2,TOB1 |
| 7.156e-03 | -4.94 | EID1 (EP300 interacting inhibitor of differentiation 1) | protein interactions | 23741 | 48 | 15 | 17029 | 2761 |
MAGED2,RB1,FBXO21,MDM2,MAGEH1,JAK1,KAT2A,ASPM,CUL1,DNAJA1,MYO9B,ARID4A,NCOA2,PFKP,MYO5A |
| 7.156e-03 | -4.94 | CDK11B (cyclin dependent kinase 11B) | protein interactions | 984 | 48 | 15 | 17029 | 2761 |
RAP1A,HSPA4,RBM25,KMT2E,RPS27A,PIN1,KAT7,RNPS1,UHRF2,JMJD6,YWHAZ,CCNL2,CDK11B,CDK11A,CDC37 |
| 7.156e-03 | -4.94 | NOL6 (nucleolar protein 6) | protein interactions | 65083 | 48 | 15 | 17029 | 2761 |
UTP20,MEX3C,NOP2,AATF,DDX24,SIAH1,ZNF512,MECP2,ZNF746,NOC2L,EBNA1BP2,FBL,UBE2I,DHX15,IFI16 |
| 7.156e-03 | -4.94 | FAM174A (family with sequence similarity 174 member A) | protein interactions | 345757 | 48 | 15 | 17029 | 2761 |
INTS2,CTU2,RAD51C,PDCD10,TMEM168,FAM118B,NF1,GOPC,LTN1,CBWD1,TNPO2,GUF1,GPD1L,PDXDC1,MAD2L2 |
| 7.167e-03 | -4.94 | p38 signaling mediated by MAPKAP kinases | Pathway Interaction DB | p38_mk2pathway | 20 | 9 | 2226 | 426 |
TSC2,MAPKAPK3,RAF1,TCF3,YWHAZ,CDC25B,CREB1,YWHAH,MAPK14 |
| 7.173e-03 | -4.94 | PDGFRA (platelet derived growth factor receptor alpha) | protein interactions | 5156 | 66 | 19 | 17029 | 2761 |
SNX2,VHL,RNPS1,FLOT1,RRM2,BRCA1,MAK16,TFRC,CRKL,JAK1,PTEN,PPIL2,DNM2,PTPN11,STAT1,CLU,H3F3A,SMURF1,STAT3 |
| 7.173e-03 | -4.94 | LOC101929876 (40S ribosomal protein S26) | protein interactions | 101929876 | 66 | 19 | 17029 | 2761 |
RPS2,RPL35,RPLP2,RPS10,RPL6,RPL38,RPL8,RPL15,RPL27A,RPS9,RPSA,RPL11,RPL23A,RPL36,RPS14,RPLP1,RPL19,TMED2,SLC25A1 |
| 7.173e-03 | -4.94 | NSD2 (nuclear receptor binding SET domain protein 2) | protein interactions | 7468 | 66 | 19 | 17029 | 2761 |
BRD4,RPL6,RPL8,DDX20,THRAP3,PLEC,KIF11,TRIM28,APP,GEMIN5,DTL,PCNA,DGCR8,GEMIN4,ZC3H3,ZC3HAV1,IFI16,GPATCH4,HDAC2 |
| 7.173e-03 | -4.94 | GPS1 (G protein pathway suppressor 1) | protein interactions | 2873 | 66 | 19 | 17029 | 2761 |
COPS8,FGFR1OP,RBX1,CUL3,CUL1,USP48,GFER,IRF5,BTBD1,POLR2A,SAP130,PSMA6,TBC1D17,FBXO7,DCAF11,COPS7B,COPS6,UBE2M,DDB1 |
| 7.173e-03 | -4.94 | ARID1A (AT-rich interaction domain 1A) | protein interactions | 8289 | 66 | 19 | 17029 | 2761 |
UNK,PHF10,EWSR1,VHL,CUL3,CUL1,SMARCA4,NFATC2,PBRM1,ARID1B,TFAP4,SMAD2,BCL7C,NCOA1,SMARCE1,EYA2,CARM1,CDC5L,SMARCD1 |
| 7.173e-03 | -4.94 | USF1 (upstream transcription factor 1) | protein interactions | 7391 | 66 | 19 | 17029 | 2761 |
MAX,EWSR1,PRKDC,TRIM11,TCF3,E2F3,KLC1,SMARCA4,TOP2B,WDR5,APP,PLEKHF2,XRCC5,MAP3K4,USF1,STT3A,RBBP4,TAF6,USF2 |
| 7.173e-03 | -4.94 | STAM (signal transducing adaptor molecule) | protein interactions | 8027 | 66 | 19 | 17029 | 2761 |
UNK,UBQLN4,TRAF7,GGA1,TMEM216,RFFL,UBE4B,UBQLN2,SEC31A,HGS,JAK1,THADA,PPM1G,PRDX5,ZRANB2,AHCYL1,IGBP1,SSSCA1,USP34 |
| 7.177e-03 | -4.94 | MCCC1 (methylcrotonoyl-CoA carboxylase 1) | protein interactions | 56922 | 31 | 11 | 17029 | 2761 |
KIF5B,PTEN,HUWE1,ZNF746,METTL2A,TUFM,FOXRED1,EEF1D,ECH1,NDUFS7,DCTN1 |
| 7.177e-03 | -4.94 | SLBP (stem-loop binding protein) | protein interactions | 7884 | 31 | 11 | 17029 | 2761 |
MIF4GD,UPF1,CCNA2,ZNF473,DCAF11,FEM1B,CSNK2A1,CUL1,CCNF,CDK2,TACC3 |
| 7.177e-03 | -4.94 | TLK2 (tousled like kinase 2) | protein interactions | 11011 | 31 | 11 | 17029 | 2761 |
IRF4,FEZ2,RPS27A,RPS6KA1,DYNLL1,TLK1,YWHAZ,NFATC2,CABIN1,XPO7,ASF1B |
| 7.177e-03 | -4.94 | ZRANB1 (zinc finger RANBP2-type containing 1) | protein interactions | 54764 | 31 | 11 | 17029 | 2761 |
MOB4,GCC2,KEAP1,CORO7,STRIP1,MAP4K4,STRN4,BICD2,PMF1,ALDH18A1,FGFR1OP2 |
| 7.177e-03 | -4.94 | MOAP1 (modulator of apoptosis 1) | protein interactions | 64112 | 31 | 11 | 17029 | 2761 |
MOAP1,MBIP,UBQLN4,MAGEH1,THOC1,ASPM,BCL2,SIRT2,BCL2L1,MYO9B,DDB1 |
| 7.177e-03 | -4.94 | Psmd6 (proteasome (prosome, macropain) 26S subunit, non-ATPase, 6) | protein interactions | 66413 | 31 | 11 | 17029 | 2761 |
TXNL1,PSMD2,MIF4GD,PSMD1,NUP188,PRDX3,UCHL5,PSMD8,PSMD3,PSMC1,PSMC4 |
| 7.177e-03 | -4.94 | SH3GLB2 (SH3 domain containing GRB2 like, endophilin B2) | protein interactions | 56904 | 31 | 11 | 17029 | 2761 |
SREK1,PA2G4,RHOA,PPP6R2,GIT2,PICALM,UBA5,EFTUD2,SH3GLB1,GADD45G,SH3GLB2 |
| 7.177e-03 | -4.94 | PDE6D (phosphodiesterase 6D) | protein interactions | 5147 | 31 | 11 | 17029 | 2761 |
RAB18,RAB8A,RAP1A,RHOA,CDC42,CUL1,TALDO1,HRAS,RHOB,RHEB,RAD23A |
| 7.177e-03 | -4.94 | RAC2 (Rac family small GTPase 2) | protein interactions | 5880 | 31 | 11 | 17029 | 2761 |
CDC42,ARFIP2,CUL1,ARHGDIB,ACTB,ICMT,SMAD1,CD81,SMAD4,DEF6,RTKN |
| 7.177e-03 | -4.94 | ZNF593 (zinc finger protein 593) | protein interactions | 51042 | 31 | 11 | 17029 | 2761 |
USO1,SEC23IP,CGAS,ZNF512,MECP2,DNPH1,RAB1A,LTA4H,ZNRD1,SRPK2,USP5 |
| 7.177e-03 | -4.94 | CCDC183 (coiled-coil domain containing 183) | protein interactions | 84960 | 31 | 11 | 17029 | 2761 |
PCM1,CCDC14,GRIPAP1,E2F4,CEP55,ARHGEF12,AP1B1,NDE1,RUFY1,NUP85,CDKN2A |
| 7.177e-03 | -4.94 | Atp2a2 (ATPase, Ca++ transporting, cardiac muscle, slow twitch 2) | protein interactions | 11938 | 31 | 11 | 17029 | 2761 |
INTS2,PON2,STT3A,PHB2,TAP2,ATP5F1B,ATP5F1A,PTDSS1,ESYT2,POLQ,TMEM33 |
| 7.177e-03 | -4.94 | PTMS (parathymosin) | protein interactions | 5763 | 31 | 11 | 17029 | 2761 |
ADSS,SMAD2,DCK,WDR1,PRDX5,LAGE3,TALDO1,APP,CLNS1A,RXRB,CBX3 |
| 7.188e-03 | -4.94 | regulation of protein localization to plasma membrane | biological process | GO:1903076 | 85 | 22 | 17256 | 2622 |
RHOG,PDPK1,TGFB1,GOPC,ACSL3,NKD2,CIB1,EZR,BCL2L1,RAB11A,APPL1,PICALM,PRNP,KIF5B,CDK5,PPP2R5A,CSK,CNPY4,ITGB1,VPS4A,TMBIM1,NUMB |
| 7.202e-03 | -4.93 | GSE13411_NAIVE_BCELL_VS_PLASMA_CELL_UP | MSigDB lists | GSE13411_NAIVE_BCELL_VS_PLASMA_CELL_UP | 175 | 39 | 17377 | 2626 |
SART1,CAST,UBXN1,RBM8A,NOTCH2,AP1B1,SNN,PPP1R16B,GIT2,APP,FAM192A,NFATC3,NUP210,SP100,ZCCHC2,CORO1A,TP53BP2,AQR,PIKFYVE,GCC1,PTPRK,ZNF672,PTPN18,DCLRE1C,MACF1,EML4,PLEKHF2,RBM38,PFDN5,HHEX,UPF1,CHD3,DCK,QRSL1,GALNT10,ZMAT3,NUDT3,CWC25,DDX52 |
| 7.202e-03 | -4.93 | GSE18804_BRAIN_VS_COLON_TUMORAL_MACROPHAGE_DN | MSigDB lists | GSE18804_BRAIN_VS_COLON_TUMORAL_MACROPHAGE_DN | 175 | 39 | 17377 | 2626 |
NDUFS1,TRIP12,CCM2,COMMD5,BZW2,CPNE3,HDDC2,ZNF696,SAP130,PPP1R3B,PSMD1,ATIC,JAZF1,RBM3,TCEA1,TOP1MT,PABPC1,EEF1D,EBAG9,PDLIM2,PHF20L1,GTF3C6,TSTA3,RDH10,GMFB,RPL8,BOLA1,PITPNB,PRKRA,EIF3H,XRCC5,ATAD2,STAT6,NSMCE2,ADAM9,YWHAZ,MRPL13,RNF139,IFI16 |
| 7.202e-03 | -4.93 | GSE3982_DC_VS_BCELL_DN | MSigDB lists | GSE3982_DC_VS_BCELL_DN | 175 | 39 | 17377 | 2626 |
ANKRD27,GOLIM4,RAF1,TPX2,MON1B,PLAGL2,CTCF,GTF3A,CRLF3,SYNRG,RUFY1,SRRT,GIT2,HLA-A,HDDC2,PNO1,FAM192A,ZNF473,INPP5A,CD3EAP,KIF13B,JOSD1,BCL2,FBXL7,CDC25B,EEF1D,ATP6V1G1,CYTH1,SNRNP200,NASP,RPL6,DIDO1,GLOD4,RPL37,FBXO21,JAK1,FTSJ1,KLHDC4,CHMP7 |
| 7.209e-03 | -4.93 | interstrand cross-link repair | biological process | GO:0036297 | 51 | 15 | 17256 | 2622 |
FANCL,RFWD3,RPA2,ERCC1,RPS27A,RAD51AP1,FAAP100,XPA,XRCC3,DCLRE1C,FANCE,RAD51D,WDR48,FANCI,RPA1 |
| 7.216e-03 | -4.93 | upper_aerodigestive_tract-pharynx-carcinoma | COSMIC cancer mutations | upper_aerodigestive_tract-pharynx-carcinoma | 13 | 6 | 17385 | 2587 |
CDKN2C,RB1,KRAS,NRAS,SF3B1,HRAS |
| 7.216e-03 | -4.93 | stomach-carcinoma-mucinous_adenocarcinoma | COSMIC cancer mutations | stomach-carcinoma-mucinous_adenocarcinoma | 13 | 6 | 17385 | 2587 |
KRAS,STK11,NRAS,PTEN,HRAS,MSH6 |
| 7.216e-03 | -4.93 | mucinous_adenocarcinoma | COSMIC cancer mutations | mucinous_adenocarcinoma | 13 | 6 | 17385 | 2587 |
KRAS,STK11,NRAS,PTEN,HRAS,MSH6 |
| 7.216e-03 | -4.93 | soft_tissue-fat-lipoma | COSMIC cancer mutations | soft_tissue-fat-lipoma | 13 | 6 | 17385 | 2587 |
GNAS,RB1,FUS,EWSR1,MEN1,CDKN2A |
| 7.216e-03 | -4.93 | haematopoietic_and_lymphoid_tissue-lymph_node-lymphoid_neoplasm-Burkitt_lymphoma | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-lymph_node-lymphoid_neoplasm-Burkitt_lymphoma | 13 | 6 | 17385 | 2587 |
RB1,KRAS,NRAS,PTEN,HRAS,CDKN2A |
| 7.218e-03 | -4.93 | GO_PROTEIN_PEPTIDYL_PROLYL_ISOMERIZATION | MSigDB lists | GO_PROTEIN_PEPTIDYL_PROLYL_ISOMERIZATION | 42 | 13 | 17377 | 2626 |
FKBP1A,PPIF,PPIB,CWC27,PPIG,PIN1,PPIL2,TTC9C,PPIE,FKBP5,PPWD1,FKBP2,FKBP3 |
| 7.218e-03 | -4.93 | GO_HISTONE_H4_ACETYLATION | MSigDB lists | GO_HISTONE_H4_ACETYLATION | 42 | 13 | 17377 | 2626 |
IRF4,KAT2A,KAT7,NAA50,OGT,ELP4,NCOA1,RUVBL2,USP22,BEND3,WDR5,NAA60,MEAF6 |
| 7.218e-03 | -4.93 | BIOCARTA_BIOPEPTIDES_PATHWAY | MSigDB lists | BIOCARTA_BIOPEPTIDES_PATHWAY | 42 | 13 | 17377 | 2626 |
CDK5,CALM2,SHC1,STAT6,RAF1,STAT1,MAPK14,MAPK1,STAT3,MAP2K2,HRAS,CAMK2G,MAPK3 |
| 7.222e-03 | -4.93 | DIRMEIER_LMP1_RESPONSE_LATE_UP | MSigDB lists | DIRMEIER_LMP1_RESPONSE_LATE_UP | 56 | 16 | 17377 | 2626 |
VOPP1,RHOG,MTHFD2,TRIP10,HUWE1,ATP13A3,ANP32A,AHDC1,MDFIC,PIEZO1,LYN,SLC20A1,SRRT,IRF5,CSNK1D,CFLAR |
| 7.230e-03 | -4.93 | MED31 (mediator complex subunit 31) | protein interactions | 51003 | 80 | 22 | 17029 | 2761 |
MOB4,CCNC,ORAI2,TK1,POLR2G,FAM118B,GADD45G,EPN1,NFATC2,PMF1,DAZAP2,PABPC4,RPA2,ERH,RBM23,ZBTB45,MED8,MED10,BIRC5,ELMO1,PQBP1,LYPLA2 |
| 7.230e-03 | -4.93 | GATAD2B (GATA zinc finger domain containing 2B) | protein interactions | 57459 | 80 | 22 | 17029 | 2761 |
PHF20L1,MTA2,SUZ12,SUMO2,NFATC2,BRCA1,NDUFA7,MBD3,TCF19,PARK7,HMG20A,SMAD2,KPNA1,CDC16,NDUFA2,GOLGA2,CHD3,MTA1,MBD2,UHRF2,RBBP4,HDAC2 |
| 7.230e-03 | -4.93 | USP5 (ubiquitin specific peptidase 5) | protein interactions | 8078 | 80 | 22 | 17029 | 2761 |
TXNL1,FOXM1,GNPDA1,ZFP91,PBK,XIAP,LAGE3,RFFL,DAZAP2,APP,PRDX1,CLNS1A,MCTS1,RAD23A,PCNA,TRIM26,RAD18,RAD23B,UBA5,SMURF1,DVL2,USP13 |
| 7.230e-03 | -4.93 | RRP12 (ribosomal RNA processing 12 homolog) | protein interactions | 23223 | 80 | 22 | 17029 | 2761 |
SRP72,COX15,NIFK,RPS2,DDX24,RPL6,CUL3,CUL1,CSNK2A1,KIF2C,EIF2A,BRIX1,RRP36,CAND1,DDX56,RPS14,ZNF746,NOC2L,COPS6,IFI16,GPATCH4,BYSL |
| 7.234e-03 | -4.93 | - | gene3d domains | 3.90.110.10 | 9 | 5 | 8148 | 1295 |
MDH1,UEVLD,MDH2,LDHA,LDHB |
| 7.262e-03 | -4.93 | GSE411_UNSTIM_VS_100MIN_IL6_STIM_MACROPHAGE_UP | MSigDB lists | GSE411_UNSTIM_VS_100MIN_IL6_STIM_MACROPHAGE_UP | 186 | 41 | 17377 | 2626 |
CYTIP,PKP4,C19orf53,SRGN,MAGED1,KCTD17,RRAGC,RAB11A,MFSD10,MXD1,KIAA1147,AHCTF1,NUP210,ETV6,FOXN2,SLC12A2,ATP6V0D1,S100A6,PSRC1,TK1,CREG1,COQ10B,RPS10,MKI67,LNX2,PDE3B,ZFAND5,RPSA,NEU1,FAS,AKAP1,PI4K2A,HINT1,CCDC6,TPP2,SNAP29,TFDP1,ITGB1,PITPNA,BTF3,IGBP1 |
| 7.262e-03 | -4.93 | GSE30083_SP1_VS_SP3_THYMOCYTE_UP | MSigDB lists | GSE30083_SP1_VS_SP3_THYMOCYTE_UP | 186 | 41 | 17377 | 2626 |
HIVEP3,C19orf53,NOP2,TMBIM4,MAGED1,HMGN3,SLC35B1,WRB,PIP4K2A,TFRC,RAD23A,SAR1A,MRPL54,SMARCE1,GPX4,COPS8,PPAN,FTL,KLF10,TSPAN31,GTPBP4,CAMSAP1,ITM2A,PTTG1IP,TSR2,NUCB1,TIMM13,CCDC86,PRDX5,MAPK6,NDUFA11,WDR4,ADAM9,ASNA1,ATF6,ST3GAL2,SPRYD4,CD81,SSSCA1,N4BP2L2,IPO4 |
| 7.262e-03 | -4.93 | GSE16385_MONOCYTE_VS_12H_ROSIGLITAZONE_IL4_TREATED_MACROPHAGE_DN | MSigDB lists | GSE16385_MONOCYTE_VS_12H_ROSIGLITAZONE_IL4_TREATED_MACROPHAGE_DN | 186 | 41 | 17377 | 2626 |
TMEM106C,LYRM4,TP53RK,TSC22D3,UBE2Z,ARFIP2,CDK13,EIF1B,DUSP22,PABPC4,CSDE1,SAR1A,RAD23B,AP2B1,PIK3IP1,ALDH18A1,FBL,GM2A,ELOVL5,PPP3CA,CYTH1,RHOA,PPP1R18,SIGMAR1,TSPAN31,NARF,UTP15,IL12RB1,MEF2D,PCGF1,NDRG3,PLAA,DDOST,SAFB,E2F4,MAPK6,CAB39,SLAIN1,PSAP,FBXL3,ZNF146 |
| 7.262e-03 | -4.93 | GSE360_L_DONOVANI_VS_B_MALAYI_HIGH_DOSE_MAC_UP | MSigDB lists | GSE360_L_DONOVANI_VS_B_MALAYI_HIGH_DOSE_MAC_UP | 186 | 41 | 17377 | 2626 |
TCF12,PKP4,ATXN3,TRIP12,MPHOSPH8,SEC61G,ADO,OAT,CSNK1A1,SLC20A1,GGPS1,KTN1,MYL6B,HNRNPA2B1,TFAP4,CAPN2,MCM5,LTN1,MDFIC,NUP153,ATF2,TIPARP,KDM3B,CLPTM1,YTHDC1,CCDC57,POLR2D,CAPZA2,H2AFV,ARMC8,ANKRD46,DDX17,SH3BP5,OSBPL8,GOLGA8A,CAPN7,TAF12,RBPJ,ATP6V1C1,TUBB,SSRP1 |
| 7.262e-03 | -4.93 | GSE46606_UNSTIM_VS_CD40L_IL2_IL5_3DAY_STIMULATED_IRF4MID_SORTED_BCELL_DN | MSigDB lists | GSE46606_UNSTIM_VS_CD40L_IL2_IL5_3DAY_STIMULATED_IRF4MID_SORTED_BCELL_DN | 186 | 41 | 17377 | 2626 |
MAX,AGRN,NF1,PTTG1,ARID5A,XIAP,C5orf30,BCL2L1,CPNE3,MXD1,SOCS6,TPST1,TIPARP,SMARCE1,MGAT5,PPA1,MYO5A,PLK3,TRAFD1,TMEM39A,ATXN1,TOR1AIP2,PPFIA3,AZI2,RHOB,NEU1,ISG15,ARF4,OPTN,EIF4ENIF1,ATP6V1D,TMEM168,RBL1,BBX,WDR59,PPP1R11,FAM126A,MAP3K5,ATP6V1C1,BRWD3,TRAF5 |
| 7.262e-03 | -4.93 | GSE2405_HEAT_KILLED_LYSATE_VS_LIVE_A_PHAGOCYTOPHILUM_STIM_NEUTROPHIL_9H_UP | MSigDB lists | GSE2405_HEAT_KILLED_LYSATE_VS_LIVE_A_PHAGOCYTOPHILUM_STIM_NEUTROPHIL_9H_UP | 186 | 41 | 17377 | 2626 |
RMND5A,TXN,MAGED1,CENPF,CERK,CDCA8,NUF2,KIF2C,STMN1,CDKN2C,NFATC3,CLIC4,DUT,PRC1,C12orf75,SYTL3,LDHB,SAP30,ASPM,PBK,MIER1,MKI67,RRM2,CKAP2L,CDC6,KIF11,CHCHD6,ASF1B,CYB5A,KIF18B,ETS2,CLK3,CDCA5,LY75,KPNA2,FKBP5,HMGB2,PSAP,WDR91,CCNB2,GLCCI1 |
| 7.262e-03 | -4.93 | GSE29164_DAY3_VS_DAY7_CD8_TCELL_AND_IL12_TREATED_MELANOMA_UP | MSigDB lists | GSE29164_DAY3_VS_DAY7_CD8_TCELL_AND_IL12_TREATED_MELANOMA_UP | 186 | 41 | 17377 | 2626 |
ZCCHC9,RWDD1,CKLF,RRP15,PHB2,ZBTB37,HLA-E,DNAJB2,UROD,BABAM1,CERK,GLUD1,NIT2,PMVK,PARN,RCOR3,CHD1,JMY,SLC25A37,PAIP2,NDUFA2,TBC1D14,CAPZA1,EI24,AKR1B1,NDUFB9,SLC35A1,DRAM2,MRPL16,POLG2,FKBP3,BTBD1,MAN2A2,FNTA,QARS,STX18,WIPI2,SNRPG,CLU,TATDN1,ZC3HAV1 |
| 7.262e-03 | -4.93 | GSE5589_IL6_KO_VS_IL10_KO_LPS_AND_IL6_STIM_MACROPHAGE_45MIN_UP | MSigDB lists | GSE5589_IL6_KO_VS_IL10_KO_LPS_AND_IL6_STIM_MACROPHAGE_45MIN_UP | 186 | 41 | 17377 | 2626 |
GCLM,HECA,ZCCHC8,UBN1,TPX2,GGA2,LYN,FASTKD3,OIP5,TNS3,DAD1,TBC1D14,SUCLG2,SLC38A10,RBM3,SLC35C2,DNMT1,TMEM9,ABCC1,NIPSNAP1,SNX2,FOPNL,RAD51AP1,MFNG,PACS1,CDC6,CDCA2,PRPSAP1,PRIM1,EIF4ENIF1,PCM1,PALB2,POLE,ELMO1,ZNF367,TFDP1,CENPT,MAP3K5,ESPL1,LRP8,SVIP |
| 7.262e-03 | -4.93 | GSE43955_TH0_VS_TGFB_IL6_TH17_ACT_CD4_TCELL_20H_UP | MSigDB lists | GSE43955_TH0_VS_TGFB_IL6_TH17_ACT_CD4_TCELL_20H_UP | 186 | 41 | 17377 | 2626 |
WASF2,IER2,SYS1,SCOC,ANKH,HNRNPUL2,ALKBH5,PCBP1,PITHD1,MXD1,PAPOLA,KRR1,RPA2,MRPL50,MDM2,VASP,ZNF260,CITED2,SMC4,RLIM,CSTF1,HP1BP3,IFRD1,PPP3CA,POLR2L,KLF10,RPS10,CDC23,NEU1,ZFR,RHOB,FAM110A,PDRG1,PRPS2,TBPL1,PKD2,ST3GAL2,BRWD3,CHPT1,ZNF146,TMEM131 |
| 7.262e-03 | -4.93 | GSE3039_CD4_TCELL_VS_ALPHAALPHA_CD8_TCELL_UP | MSigDB lists | GSE3039_CD4_TCELL_VS_ALPHAALPHA_CD8_TCELL_UP | 186 | 41 | 17377 | 2626 |
WSB2,PPP1R37,GCLM,GPR132,TP53RK,SUCLG1,DCTN2,PLXNA1,AKT1S1,AP3S1,ABHD16A,CYHR1,ATP6V0B,KLF16,SH3BP1,DDA1,BRI3,GLTP,MAVS,ATP6V0D1,MYO5A,BAK1,PPIF,PPP1R18,GUK1,ADRB2,AMDHD2,TOMM40,ARF4,SOCS7,OPTN,PLD3,PON2,SLC38A7,FASTK,WNT5B,ATXN2L,SAMD8,RGL1,NRBP1,HRAS |
| 7.262e-03 | -4.93 | GSE29618_BCELL_VS_PDC_DN | MSigDB lists | GSE29618_BCELL_VS_PDC_DN | 186 | 41 | 17377 | 2626 |
PPIB,TXN,KIAA0100,TRIP10,MAGED1,UCK2,TM9SF3,NDUFA4,MAN2B1,FKBP2,SLC20A1,BCAP31,PARK7,APP,KIF5B,IRF4,RPN1,ASAP2,EIF4A3,DPYSL2,GRSF1,RIMS3,ETV6,RRBP1,RPN2,SCAMP4,TAGLN2,MARCH2,MLEC,SEC61B,GUK1,IDH3A,BTAF1,SELPLG,WDR1,SOX4,SCARB2,TMED10,CORO1C,ST3GAL2,HDAC2 |
| 7.262e-03 | -4.93 | GSE2770_IL12_VS_TGFB_AND_IL12_TREATED_ACT_CD4_TCELL_48H_UP | MSigDB lists | GSE2770_IL12_VS_TGFB_AND_IL12_TREATED_ACT_CD4_TCELL_48H_UP | 186 | 41 | 17377 | 2626 |
DDX58,HECA,SMAP1,SYS1,GMFG,ANXA6,UBR2,C5orf30,KCTD17,BRAP,MYH9,MAN2B1,PSEN1,PITHD1,PRNP,ADD3,CRAT,TBC1D14,FNIP2,GPD1L,TNRC18,RHBDD2,GALC,PBXIP1,ZMYND11,FBXO9,ATXN1,KRAS,CAT,TRAM2,ALDH3B1,SLCO4A1,IDE,L3MBTL3,CHD3,GPS2,DUSP3,CORO1C,PRPS2,ATF6,PSAP |
| 7.262e-03 | -4.93 | GSE17721_PAM3CSK4_VS_GADIQUIMOD_8H_BMDC_DN | MSigDB lists | GSE17721_PAM3CSK4_VS_GADIQUIMOD_8H_BMDC_DN | 186 | 41 | 17377 | 2626 |
OTUD5,PRPF38B,PARP12,TMEM184B,ZCCHC8,AP3M2,TBC1D13,CHAC2,RGS2,LYN,CUTC,ANKIB1,CDC73,MBD4,TMCC3,PRNP,MDM2,PRDM4,ARL6IP1,AFF1,RNF135,STAT3,ENPP4,DDX24,RFFL,MCL1,BRCA1,NMT2,TRIM26,TMEM168,RBL1,MAPK6,ITGB1,CHMP4B,NAA20,RUFY3,MRPL13,NRBP1,CBX4,CDKN2A,TMEM131 |
| 7.262e-03 | -4.93 | GSE16385_IFNG_TNF_VS_IL4_STIM_MACROPHAGE_UP | MSigDB lists | GSE16385_IFNG_TNF_VS_IL4_STIM_MACROPHAGE_UP | 186 | 41 | 17377 | 2626 |
RAB14,ABCA3,CASP6,IVNS1ABP,HLA-E,ANKH,TAP1,AP3M2,SUMF1,GLUD1,MYO9B,TWF2,CMTM6,PIP5K1C,TNS3,VASP,GLIS2,MBD2,SRI,AP2B1,MAP3K14,MTPN,S100A6,PCBP2,CFL1,PPP1R18,PGGT1B,ERLIN1,MTMR6,MIER2,THNSL1,PSMB9,TMEM127,HIPK2,CTSA,NCOA1,AKNA,MYO9A,DYNC1LI2,STARD3NL,S100PBP |
| 7.270e-03 | -4.92 | MXD3 (MAX dimerization protein 3) | protein interactions | 83463 | 27 | 10 | 17029 | 2761 |
SAP130,BRMS1,MAX,SMC3,ASPM,EDEM2,RCOR3,SAP30L,ZMYM3,SAP30 |
| 7.270e-03 | -4.92 | MRPS18A (mitochondrial ribosomal protein S18A) | protein interactions | 55168 | 27 | 10 | 17029 | 2761 |
NOL12,MRPL50,ZNF317,MRPL9,CYLD,MRPL42,MRPL39,RPL6,APP,NIPSNAP1 |
| 7.270e-03 | -4.92 | SUDS3 (SDS3 homolog, SIN3A corepressor complex component) | protein interactions | 64426 | 27 | 10 | 17029 | 2761 |
SAP130,BRMS1,FOXK1,PHF23,CSNK2A1,SINHCAF,MXD1,DDB1,HDAC2,SAP30 |
| 7.270e-03 | -4.92 | MINOS1 (mitochondrial inner membrane organizing system 1) | protein interactions | 440574 | 27 | 10 | 17029 | 2761 |
CHCHD3,GSTK1,UNK,IMMT,MTHFD2,MTX1,COA7,MAPK1,TUBGCP2,MTX2 |
| 7.270e-03 | -4.92 | DENND2D (DENN domain containing 2D) | protein interactions | 79961 | 27 | 10 | 17029 | 2761 |
HSPA4,BRD2,TPP2,RNPS1,C1orf35,RTF1,TCOF1,FBXL19,COIL,HSPA1B |
| 7.270e-03 | -4.92 | RPRD2 (regulation of nuclear pre-mRNA domain containing 2) | protein interactions | 23248 | 27 | 10 | 17029 | 2761 |
RPA2,UPF1,POLR2G,DGCR8,CSNK2A1,CTR9,MPG,RPRD1B,STRAP,RPA1 |
| 7.270e-03 | -4.92 | Pcna (proliferating cell nuclear antigen) | protein interactions | 18538 | 27 | 10 | 17029 | 2761 |
PCNA,PTEN,CENPJ,SIVA1,USP32,MSH2,MRPL54,RFC2,DNMT1,ANKHD1 |
| 7.270e-03 | -4.92 | CORO7 (coronin 7) | protein interactions | 79585 | 27 | 10 | 17029 | 2761 |
MRPL50,KLHL20,RBX1,AP1M1,CUL1,ACTB,ZRANB1,BLM,TOB1,ASB6 |
| 7.270e-03 | -4.92 | MRPS33 (mitochondrial ribosomal protein S33) | protein interactions | 51650 | 27 | 10 | 17029 | 2761 |
NOL12,CDKN2AIP,RBM42,MRPS2,MRPS15,RPL6,MRPS27,TRMT10B,SNRNP70,ZC3H3 |
| 7.270e-03 | -4.92 | UTP25 (UTP25, small subunit processor component) | protein interactions | 27042 | 27 | 10 | 17029 | 2761 |
UTP25,PPAN,CDKN2AIP,MYO18A,AP2B1,PPP6R3,RUFY1,ARRB2,APP,AP2S1 |
| 7.270e-03 | -4.92 | COL4A3BP (collagen type IV alpha 3 binding protein) | protein interactions | 10087 | 27 | 10 | 17029 | 2761 |
CSNK1G2,FTL,TRAF7,EYA1,ARL6IP1,PTAR1,RANGAP1,RUFY1,RTN3,MARK2 |
| 7.275e-03 | -4.92 | - | gene3d domains | 1.10.600.10 | 6 | 4 | 8148 | 1295 |
NDUFAF6,GGPS1,PDSS2,FDFT1 |
| 7.275e-03 | -4.92 | - | gene3d domains | 1.10.10.790 | 6 | 4 | 8148 | 1295 |
SUGP1,CHERP,SUGP2,U2SURP |
| 7.275e-03 | -4.92 | - | gene3d domains | 3.10.20.380 | 6 | 4 | 8148 | 1295 |
DVL1,AXIN1,DVL2,AXIN2 |
| 7.281e-03 | -4.92 | GO_LATE_ENDOSOME | MSigDB lists | GO_LATE_ENDOSOME | 197 | 43 | 17377 | 2626 |
RAB14,CHMP2A,ANKRD27,ANKRD13D,GNPNAT1,ANXA6,LAMTOR3,VTI1A,ARF1,TMEM165,RAB11A,WDR48,SPPL2A,SLC31A1,RAP1A,PIKFYVE,F2R,TMEM9,MYO5A,CLCN3,ATG9A,RAB7A,KCNQ1,CHMP2B,ZP3,RAB22A,MAP2K2,RHOB,MAPK3,DERL1,HGS,OSBPL11,CHMP4A,VPS26B,CHMP4B,VPS4A,CLN3,MAPK1,SNX14,CHID1,ZC3HAV1,VPS29,STARD3NL |
| 7.281e-03 | -4.92 | HALLMARK_GLYCOLYSIS | MSigDB lists | HALLMARK_GLYCOLYSIS | 197 | 43 | 17377 | 2626 |
MIF,GALK1,TXN,UGP2,AGRN,DEPDC1,CASP6,GNPDA1,MDH2,GNE,SDC2,B4GALT1,B4GALT4,STMN1,EXT2,POLR3K,COPB2,HOMER1,GOT2,FUT8,TPST1,ECD,TALDO1,CITED2,CLN6,ALDH9A1,SAP30,B3GALT6,NASP,TSTA3,NSDHL,LDHA,GALK2,CYB5A,PSMC4,KIF2A,ANKZF1,MDH1,NANP,PGAM1,CHPF2,B4GALT2,PFKP |
| 7.283e-03 | -4.92 | TCA Cycle and Deficiency of Pyruvate Dehydrogenase complex (PDHc) | WikiPathways | WP2453 | 16 | 7 | 5312 | 837 |
SUCLG2,MDH1,OGDH,IDH3A,SDHA,CS,ACLY |
| 7.300e-03 | -4.92 | MODULE_16 | MSigDB lists | MODULE_16 | 495 | 95 | 17377 | 2626 |
TMEM106C,POLA2,TCF12,RHOG,FOXM1,ADAM10,RPS6KA1,PTTG1,SLC2A1,TPX2,TMEM97,KLHL18,CSNK2A1,PTP4A3,GYG1,ORC1,STMN1,SSR1,CDKN2C,RAB8A,RAP1A,PCNA,CCNA2,TNFAIP8,SH3BP1,AP1M1,CORO1A,DNMT1,OGG1,PRPF19,PLK3,PLK1,BRD4,HMGN4,MRPL12,VDAC2,PSMG1,SLBP,ARHGDIB,AURKB,PKMYT1,MCM2,CCNF,CHAF1A,HSPB11,WAS,AGPAT2,PTPN7,H2AFX,DVL1,TFDP2,PPP5C,RPS26,SRGN,RRM1,MAN2B1,TFRC,NUP205,MCM5,BDH1,MSH2,GTSE1,ARHGEF2,CITED2,TTLL12,IMPA2,TMX1,MSH6,SLC25A1,FDFT1,TGFB1,PHF10,TK1,MAPKAPK3,CREG1,PRKDC,MYBL2,ILF3,EMP3,ADSL,ARID1A,TOMM40,DDX39A,KIF11,IRF5,RPA1,SYNCRIP,TFDP1,DTX4,NUP62,ZMIZ1,CDK2,UBE2C,ESPL1,MRPL3 |
| 7.303e-03 | -4.92 | MCOLN3 (mucolipin 3) | protein interactions | 55283 | 57 | 17 | 17029 | 2761 |
ABCA3,ERMP1,TMX4,SLC12A9,WRB,ABHD16A,RDH11,SCAP,IMPAD1,UPK3BL1,TMEM219,CYB5R1,TTC17,SLC12A2,SNX14,SRPK2,TMEM131 |
| 7.303e-03 | -4.92 | SLC1A5 (solute carrier family 1 member 5) | protein interactions | 6510 | 57 | 17 | 17029 | 2761 |
ZDHHC18,COX15,GPR89A,CUL3,TMEM216,ADRB2,MCM2,VDAC1,NCDN,CAND1,MASTL,TBC1D17,NEK6,MBOAT1,XRCC3,FUS,ECPAS |
| 7.325e-03 | -4.92 | Signaling by FGFR2 IIIa TM | REACTOME pathways | R-HSA-8851708 | 19 | 8 | 10287 | 1696 |
POLR2I,POLR2G,POLR2L,POLR2J,POLR2K,POLR2A,GTF2F1,POLR2D |
| 7.325e-03 | -4.92 | KSRP (KHSRP) binds and destabilizes mRNA | REACTOME pathways | R-HSA-450604 | 19 | 8 | 10287 | 1696 |
EXOSC6,EXOSC7,EXOSC1,KHSRP,YWHAZ,EXOSC9,PARN,MAPK14 |
| 7.325e-03 | -4.92 | Miscellaneous transport and binding events | REACTOME pathways | R-HSA-5223345 | 19 | 8 | 10287 | 1696 |
NIPAL3,ADD3,ADD1,MAGT1,ANKH,MRS2,NIPA2,NIPA1 |
| 7.329e-03 | -4.92 | preribosome, large subunit precursor | cellular component | GO:0030687 | 25 | 9 | 18223 | 2701 |
NSA2,PPAN,RRP15,NIP7,NOC2L,EBNA1BP2,RRS1,MAK16,FTSJ3 |
| 7.385e-03 | -4.91 | microtubule organizing center part | cellular component | GO:0044450 | 173 | 38 | 18223 | 2701 |
BCCIP,FGFR1OP,MZT1,FAM92A,MECP2,POC1A,FLOT1,CNTROB,SIRT2,TUBGCP2,SPAG5,CEP104,RAB8A,STARD9,MZT2A,CCP110,CENPJ,RP2,CEP63,POC5,DCTN1,FOPNL,TUBGCP5,TOPORS,BRCA1,CCNF,HSPA1B,KIF2A,NEK1,PCM1,CCDC14,CEP55,ODF2,ROCK1,CFAP20,WDR62,SASS6,MZT2B |
| 7.388e-03 | -4.91 | ONDER_CDH1_TARGETS_1_DN | MSigDB lists | ONDER_CDH1_TARGETS_1_DN | 159 | 36 | 17377 | 2626 |
HSPH1,MAX,MCM10,MPHOSPH8,TOR1AIP1,DHX9,ETS1,SCYL2,PNO1,RFWD3,KIF5B,SUB1,SP100,RNFT1,IL6ST,ATP13A3,SEPT11,EIF5,HNRNPM,TMX1,KLF10,ILF3,FBXO9,CDC6,BCLAF1,DNAJA1,CBFB,EML4,UTP20,SYNCRIP,CDC27,MAP4,SLC16A1,SRSF3,RRS1,DDX52 |
| 7.388e-03 | -4.91 | GSE27241_WT_VS_RORGT_KO_TH17_POLARIZED_CD4_TCELL_DN | MSigDB lists | GSE27241_WT_VS_RORGT_KO_TH17_POLARIZED_CD4_TCELL_DN | 159 | 36 | 17377 | 2626 |
COX15,SUMO2,OLA1,SUMF1,IFT27,RAB11A,RHBDD1,GTF2F1,RTKN,CALM2,MED10,NDUFB4,DUT,NUP107,ANP32A,CYC1,FDFT1,NIPSNAP1,GINS1,RPAP3,NXT1,RFC3,POLR2G,PPT1,POLR2D,EMP3,SEPT8,CDC6,HAGH,TAZ,CLNS1A,TIMM17A,STX18,ACAT1,ABCA1,NXT2 |
| 7.392e-03 | -4.91 | negative regulation of transcription, DNA-templated | biological process | GO:0045892 | 1166 | 207 | 17256 | 2622 |
RORB,TXN,ZNF496,MAX,H2AFZ,KDM4A,TSC22D3,TRIM11,SIRT2,UBE2I,CREM,CDK5,PA2G4,CIPC,GLIS2,ZNF639,JAZF1,ETV6,NOC2L,CRY2,FNIP2,SMARCE1,DNMT1,ARID4A,RYBP,PTPRK,PLK1,PLK3,SP3,DEAF1,KLF10,PBXIP1,NCK1,BAZ2A,GABPA,VHL,EHMT1,RIOX2,EZR,DDX20,AURKB,BRCA1,DOT1L,PAF1,BRMS1,HHEX,SMAD2,RPS27A,RPS14,AXIN1,PRDX5,ZNF268,TFDP2,BEND6,HDAC2,PDCD4,ZNF564,UBE2D3,PHB2,CENPF,CTCF,MEF2A,DNAJB1,PSEN1,CDC73,LYAR,TFAP4,RB1,MLX,NFATC3,KLF16,MBD2,HDAC7,ZNF746,PHF14,CTR9,TIMELESS,MDFIC,YBX1,MCPH1,TNRC18,ZNF189,ETV3,FOXK1,CIC,MTA2,LDB1,BCLAF1,RTF1,ARID1A,CBFA2T2,ZNF174,PHF6,XRCC5,PFDN5,ETS2,QARS,NFIL3,ZFP90,YY1,CDK2,N4BP2L2,CDKN2A,MBD1,ZNF296,DNMT3A,MPHOSPH8,FOXM1,SUZ12,UBR2,MAGED1,WDTC1,SMARCA4,IRF3,DUSP22,RCOR3,MXD1,HNRNPA2B1,SPINDOC,SAP130,ZBTB21,MDM2,SHC1,SP100,CDKN1B,RBM15,ATF2,STRAP,CGGBP1,RLIM,MOSPD1,SAP30,FAM172A,ZNF500,ERF,EID1,DRAP1,BTG2,PCGF6,CUL3,ATXN1,NFATC2,H2AFV,MBD3,TRIM28,CHCHD3,ZNF282,RBL1,MAFK,HIPK2,STAT6,ARNTL,H2AFX,DNAJC17,STAT1,BEND3,H3F3A,SMAD4,LRP8,CBX4,NCOR2,DEPDC1,DAP,MECP2,TCF3,ARID5A,PAWR,NKRF,MXD4,FOXO3,HMG20A,MAD2L2,WWP2,PTPN2,SUV39H2,KMT5A,H2AFY,BRD7,CITED2,CREB1,STAT3,NCOA2,RBM15B,TSHZ1,TGFB1,PSPC1,ZNF202,BTAF1,ILF3,RCOR1,PRMT2,MEN1,ZP3,CBX3,BIRC5,GPS2,ZHX1,PITX1,E2F1,PML,HMGB2,DDX5,RBPJ,NR2F2,IGBP1,PURA,IFI16 |
| 7.401e-03 | -4.91 | polyubiquitin modification-dependent protein binding | molecular function | GO:0031593 | 46 | 14 | 17224 | 2647 |
UBQLN4,BABAM2,TNFAIP3,RAD18,ABRAXAS2,TAB2,RAD23B,UBXN1,WDR81,ZRANB1,PARP10,RNF169,OPTN,RAD23A |
| 7.417e-03 | -4.90 | negative regulation of cyclin-dependent protein kinase activity | biological process | GO:1904030 | 33 | 11 | 17256 | 2622 |
PLK1,TFAP4,CDKN2C,HHEX,TNFAIP3,PTEN,FBXO7,CDKN1B,MEN1,NR2F2,CDKN2A |
| 7.417e-03 | -4.90 | nuclear-transcribed mRNA poly(A) tail shortening | biological process | GO:0000289 | 33 | 11 | 17256 | 2622 |
CNOT9,SAMD4B,EIF4A3,CNOT6,CNOT6L,PARN,CNOT11,PABPC1,TUT4,CNOT3,PAIP1 |
| 7.423e-03 | -4.90 | histone acetyltransferase activity | molecular function | GO:0004402 | 60 | 17 | 17224 | 2647 |
KAT2A,KAT7,TEX30,NAA50,OGT,ELP4,KANSL2,TAF5L,EDF1,TAF6L,NCOA1,TAF12,USP22,WDR5,SUPT7L,ATF2,NAA60 |
| 7.429e-03 | -4.90 | Bladder Cancer | WikiPathways | WP2828 | 32 | 11 | 5312 | 837 |
FGFR3,RB1,MDM2,PIK3R2,E2F1,DAPK1,MAPK1,HRAS,MAP2K2,CDKN2A,DAPK3 |
| 7.434e-03 | -4.90 | response to oxygen levels | biological process | GO:0070482 | 365 | 73 | 17256 | 2622 |
DNMT3A,NF1,RAF1,ALKBH5,SIRT2,SLC29A1,CCNB1,BECN1,BIRC2,EEF2K,USF1,CCNA2,PSMA6,MDM2,PSMD1,CDKN1B,ATP6V1G1,PLK3,RBX1,PSMA8,VHL,PSMB7,PSMB9,SCAP,RPS27A,PSMD8,PSMD3,HIPK2,PSMC1,SMAD4,HDAC2,UBE2D3,PHB2,TM9SF4,AGTRAP,MECP2,PRKAA1,PSMD9,ETS1,FOXO3,LMNA,CFLAR,CAPN2,PSMD2,TIGAR,SUV39H2,PTEN,ATP6V0A2,AHCY,BCL2,CREB1,CITED2,ATP6V0D1,HP1BP3,TGFB1,ADAM17,RHOA,ERO1A,LDHA,ADSL,PSMA1,PKM,PSMB3,PSMC4,FAS,CAT,TSC1,PDLIM1,PML,E2F1,RBPJ,CPEB2,EGLN1 |
| 7.441e-03 | -4.90 | membrane protein complex | cellular component | GO:0098796 | 1151 | 200 | 18223 | 2701 |
TMED7,COPA,NDUFB6,UQCR10,PIGQ,TAP1,AP3M2,ATP5PF,BECN1,SYNRG,BIRC2,PARK7,CALM2,NAPG,TIMM23,AP3S2,IL6ST,PIK3R2,AP1M1,AP2B1,NDUFB9,SPTSSA,KCNAB2,TIMM50,BAK1,SGCE,APH1A,GNG7,LRP5,IL12RB1,KRTCAP2,STX16,FOXRED1,NECAP2,STOML2,STT3A,TMED10,TIMM29,ITGB1,COX5A,VIPAS39,UQCRH,ATP6V0C,VPS4A,TRAF5,ATP6V0E1,SVIP,NDUFV2,COX5B,GGA1,HLA-E,UBXN1,LAMTOR3,NDUFA4,COX4I1,TMED3,ITGB5,APH1B,PSEN1,VPS25,COPG2,NDUFS7,NPLOC4,COPB2,CFLAR,NDUFS4,FKBP1A,RPN1,PYURF,LRRC8D,DAD1,ARL6IP1,ATP6V0A2,BCL2,CYC1,LRSAM1,GNAI2,ATP6V0D1,ATP5IF1,PIGT,SYVN1,TOMM40,GOSR1,FAS,EVC2,DERL1,GNAS,SDHB,SEC31A,ORMDL2,SNAP23,LAMTOR4,ATP5F1A,MAP3K5,RNF139,NDUFA5,SNX27,CHMP2A,TOMM20,IMMT,COPE,VTI1A,RRAGC,MYH9,CLCC1,AP1B1,ATP6V1B2,PRKACA,LYN,EXT2,BCAP31,SDHA,SEC11A,ATP6V0B,SHC1,SAR1A,MICU2,RPN2,TAP2,CLTB,APOOL,GM2A,HTRA2,DCTN1,ATP6V1G1,SNX8,PPIF,SEC61B,RAB7A,SLC26A6,VDAC2,DMAC2,ATP6V0A1,LRRC8A,NDUFA7,NDUFB1,CHMP2B,VDAC1,AP4E1,TOLLIP,PEF1,CHCHD3,ANKZF1,ATP1A1,CHMP4A,DDOST,VPS26B,TIMM17A,CORO1C,TOMM6,NDUFA11,SEL1L,AP1S1,CHMP4B,AP2S1,NDUFS1,SESTD1,SCYL1,FLOT1,TIMM21,ATP5F1B,GGA2,AP3S1,HLA-A,TFRC,CLIC4,NDUFV1,NDUFA2,ITGB8,NDUFB4,SEC24C,NDUFS8,OSTC,SGCB,NDUFA3,RNF5,SNX2,DENND4C,ABCF2,KCNQ1,ATP5MF,CHCHD6,PICALM,FADD,HLA-B,GNA12,CACNB1,PDCD6,ATP6V1D,MAGT1,ATP5MC3,SNAP29,STX18,COX8A,NDUFS5,SPCS3,ATP6V1C1,CHMP7,VPS29,FAF1 |
| 7.471e-03 | -4.90 | GO_CELLULAR_RESPONSE_TO_INSULIN_STIMULUS | MSigDB lists | GO_CELLULAR_RESPONSE_TO_INSULIN_STIMULUS | 143 | 33 | 17377 | 2626 |
WDTC1,ATP6V1B2,AP3S1,EEF2K,PTPN2,ATP6V0B,PDK2,USF1,RAB8A,SHC1,PIK3R2,ATP6V0A2,ATP6V0D1,MYO5A,ATP6V1G1,PDPK1,PRKDC,AKT2,DENND4C,ATP6V0A1,SRSF5,PDE3B,APPL1,SOCS7,ATP6V1D,IDE,OGT,ATP6V0C,ATP6V1C1,CDK2,ATP6V0E1,CPEB2,SLC25A33 |
| 7.475e-03 | -4.90 | small molecule metabolic process | biological process | GO:0044281 | 1803 | 310 | 17256 | 2622 |
TXN,PPCS,NDUFB6,HEXB,GLUD1,NANS,UBE2I,OAT,PARK7,USF1,MECR,UPRT,SUCLG2,SLC26A2,KCNAB2,AKT2,AMDHD2,STOML2,COX5A,MLYCD,DHTKD1,ST3GAL2,UQCRH,CHPF2,PFKP,B4GALT2,NDUFV2,COX5B,MUT,ADO,PRKAA1,RRM1,RAB23,B4GALT1,NDUFA4,CYCS,MAN2B1,PDXDC1,NDUFS7,NDUFS4,GNS,PDXP,INPP5A,ATIC,BDH1,CTPS1,MSH2,TPST1,ATP6V0A2,CYC1,PPA1,APOL1,FDFT1,CARS2,COQ8A,ERO1A,RDH10,DCTD,PKM,KDM3A,MTR,CYB5A,RDH11,CAT,ADSS,EPRS,SCARB2,MTHFD2,DCK,QARS,ACLY,MDH1,GPI,PLPP6,HEXA,ACSF2,NUDT3,EGLN1,KARS,TRERF1,OLA1,WDTC1,NIT2,SLC35B2,ADPGK,EFL1,SDHA,APP,CD320,ABHD16A,NUDT19,FLAD1,DECR1,DUT,LPIN2,ADCY9,TALDO1,CLN6,GPD1L,PDCL3,ADCY7,GPX4,ENPP4,IDH3A,ATP6V0A1,PFKFB3,GALK2,NDUFA7,TAZ,POLG2,SERP1,MAT2A,ALDH3B1,HINT1,GUCY1B1,NT5C3B,PPA2,PDXK,B4GALT3,GALK1,NDUFS1,B4GALT5,MECP2,MRI1,TKT,SLC25A12,ABHD14B,IP6K2,ATP5F1B,SPR,PMVK,POFUT1,NEIL2,EBP,MAT2B,ERH,NDUFA2,GATC,COQ4,NDUFB4,PTEN,CRAT,FUT8,NDUFA3,IMPA2,LYPLA2,LDHB,TK1,GUK1,MRS2,LDHA,ADSL,PDE3B,ECH1,SLC19A1,ATP5MC3,ACOX1,PARG,NAXE,SLC25A19,NDUFS5,PARP10,ADA2,COX15,LYRM4,GNPDA1,UQCR10,MCCC1,MAPK14,ATP5PF,BCAT2,PCYOX1L,CREM,MBD4,GOT2,IMPAD1,HADHB,PPCDC,AKR1B1,NDUFB9,TECR,OGG1,CARMIL1,ABCC5,LARS,DPM1,HARS,RRM2,LRP5,BRCA1,PRPSAP1,ODC1,MPC1,ABHD5,MAN2A2,UEVLD,IARS2,QRSL1,DHFR2,CLN3,NUDT11,SEPHS2,COX4I1,PM20D2,B4GALT4,EPHX2,CHKA,NUS1,SLC27A4,AHCY,ALDH18A1,ACAD8,ABCC1,ABHD2,ATP5IF1,TSTA3,AACS,ERLIN1,NSDHL,NUDT4,ACSL3,AMD1,GBA,VKORC1,SDHB,MBIP,UAP1,PRPS2,COX7A2L,TBPL1,SLC16A1,DNPH1,ATP5F1A,NANP,NIPSNAP2,PDSS2,APOL2,MMACHC,NDUFA5,PRKAB1,GNPNAT1,SUCLG1,UGP2,MDH2,MRPL39,SUMO2,SLC2A1,UCK2,UCK1,ATP6V1B2,GGPS1,ZADH2,FARSA,PDK2,IARS,CS,AHCYL1,MINPP1,CHP1,ACSL5,CGAS,HPDL,COQ10B,CPOX,GLO1,OGDH,NDUFB1,PDHX,PON2,SCAP,NDUFA11,SCARB1,MAPK1,LTA4H,ABCA1,MIF,GCLM,CMAS,NADSYN1,GNE,HDDC2,GART,NDUFV1,ABCD1,NDUFS8,PTGES3,MYO5A,RNLS,SLC25A1,TGFB1,B3GALT6,AMPD2,ELOVL5,RHOA,NADK2,PNPLA8,ATP5MF,HAGH,TARS,HSPA1B,MAPK3,PLAA,COX8A,ACAT1,IMPDH1,ACADM,IDH3B,PLOD3,PGAM1,GCSH |
| 7.476e-03 | -4.90 | parietal_lobe | COSMIC cancer mutations | parietal_lobe | 57 | 16 | 17385 | 2587 |
NRAS,NF1,SF3B1,KRAS,MEN1,MAP2K2,CDKN2C,GNAS,RBM23,FGFR3,PTEN,CLCN6,MSH2,H3F3A,MSH6,CDKN2A |
| 7.492e-03 | -4.89 | GO_NUCLEOSIDE_MONOPHOSPHATE_BIOSYNTHETIC_PROCESS | MSigDB lists | GO_NUCLEOSIDE_MONOPHOSPHATE_BIOSYNTHETIC_PROCESS | 61 | 17 | 17377 | 2626 |
TGFB1,AMPD2,TK1,UCK2,ATP6V0A1,UCK1,ADSL,STOML2,ADSS,GART,DCK,DUT,ATIC,PRPS2,UPRT,ATP6V0A2,IMPDH1 |
| 7.493e-03 | -4.89 | BONOME_OVARIAN_CANCER_SURVIVAL_OPTIMAL_DEBULKING | MSigDB lists | BONOME_OVARIAN_CANCER_SURVIVAL_OPTIMAL_DEBULKING | 225 | 48 | 17377 | 2626 |
CYLD,CKLF,DHPS,TCF3,CHD1L,CIB1,ENSA,FLOT1,MED13L,JMJD6,TBC1D13,ATG2B,TMED3,SNRPD3,GGA2,SPR,RAB11A,CMTM6,MCTS1,SP100,ARF5,PELO,CRY2,TAGLN2,CYB5R1,RNF5,RHOBTB3,SEC61B,ZNF84,RBX1,ZNF780B,PRKDC,CAMSAP1,OTUD3,LY6E,NDRG3,PDE3B,GOSR1,BTBD1,OPTN,PCM1,SPATA2,SNAP29,NCOA1,ZMIZ1,NR2F2,MYL12B,IFI16 |
| 7.498e-03 | -4.89 | human chr17q25.3 | chromosome location | human chr17q25.3 | 133 | 24 | 26185 | 2809 |
CYTH1,CCDC57,TIMP2,TK1,SEPT9,PGS1,MRPL12,NARF,USP36,NPLOC4,HGS,SGSH,BIRC5,EIF4A3,FAAP100,CANT1,FN3KRP,SLC38A10,CYBC1,PCYT2,WDR45B,CBX4,CSNK1D,CCDC137 |
| 7.508e-03 | -4.89 | regulation of DNA binding | biological process | GO:0051101 | 116 | 28 | 17256 | 2622 |
TGFB1,CPNE1,TXN,KAT2A,HJURP,CDT1,HABP4,EDF1,SIRT2,PSEN1,TRIM28,PARK7,MAD2L2,DOT1L,DDRGK1,TFAP4,RB1,IRF4,SP100,HIPK2,CDCA5,E2F1,SRI,CEBPG,HMGB2,ZFP90,HDAC2,IFI16 |
| 7.510e-03 | -4.89 | V$CREB_Q2 | MSigDB lists | V$CREB_Q2 | 253 | 53 | 17377 | 2626 |
PKP4,CYLD,SARNP,ZBTB37,TSC22D3,DNAJB2,PDAP1,CDK2AP2,ALKBH5,AGPAT1,KLF13,CTCF,RAB6A,CNTROB,UBQLN2,SLC25A37,CREM,ABHD16A,HNRNPA2B1,SLC31A1,CDC42,PPIG,ZFYVE27,JOSD1,TAGLN2,ALDH18A1,STAT3,PABPC1,RNF5,ELOVL5,CLCN3,RPRD1A,TMEM39A,ERF,RAB7A,LDHA,C1orf35,DNAJC9,OGDH,SRSF1,CBX3,SDHB,GNAS,HHEX,ORMDL2,RAB24,ZNF367,GADD45B,ADAM9,ATP6V0C,SMAD1,NUDT3,SMARCD1 |
| 7.517e-03 | -4.89 | GSE29618_BCELL_VS_MDC_DAY7_FLU_VACCINE_UP | MSigDB lists | GSE29618_BCELL_VS_MDC_DAY7_FLU_VACCINE_UP | 170 | 38 | 17377 | 2626 |
TSC2,TCF3,SMC6,PAWR,GGA2,EIF1B,ETS1,PPP1R16B,MBD4,TERF2IP,ADD3,SP100,FUT8,CDC25B,PIK3IP1,PIKFYVE,PTPRK,SRSF10,POU2AF1,SHOC2,BIRC3,KIAA0040,SNX2,MAP4K4,ZBED5,ITM2A,EZR,EAF2,CYFIP2,ODC1,PLEKHF2,PDLIM1,WDR11,FAM3C,TRAF5,CD81,CHMP7,PDCD4 |
| 7.521e-03 | -4.89 | ileum | COSMIC cancer mutations | ileum | 25 | 9 | 17385 | 2587 |
GNAS,KRAS,STK11,NRAS,MEN1,HRAS,SMAD4,CDKN2A,PTPN11 |
| 7.534e-03 | -4.89 | Shelterin complex | KEGG pathways | hsa_M00424 | 6 | 4 | 7161 | 1149 |
TERF2IP,TERF1,POT1,TERF2 |
| 7.534e-03 | -4.89 | Shelterin complex | KEGG pathways | M00424 | 6 | 4 | 7161 | 1149 |
TERF2IP,TERF1,POT1,TERF2 |
| 7.538e-03 | -4.89 | RBX1 (ring-box 1) | protein interactions | 9978 | 164 | 39 | 17029 | 2761 |
UBE2D3,UBE2E2,CORO7,MCM10,KCTD17,KLHL18,CUL1,DCUN1D4,ARID1B,APP,FBXO22,LRRC14,FBXO3,DTL,PSMA6,MED8,DDA1,FBXO7,FEM1B,FBXW2,CDKN1B,UBE2M,RHOBTB3,RBX1,VHL,CUL3,DCUN1D5,ERBIN,CCNF,RHOB,CAND1,FBXO21,KEAP1,HINT1,KBTBD7,PML,COPS6,ZC3HC1,DDB1 |
| 7.541e-03 | -4.89 | MTCH2 (mitochondrial carrier 2) | protein interactions | 23788 | 85 | 23 | 17029 | 2761 |
NDUFS1,PHB2,VDAC2,NDUFA4,ATP5F1B,TOMM40,RAB1A,MCM2,VDAC1,DUSP22,SPPL2B,SDHB,RPN1,ATP1A1,ATP2A2,NDUFA2,IMPDH1,NDUFB9,ATP5F1A,APOOL,LMAN1,GNAI2,ATP6V0D1 |
| 7.541e-03 | -4.89 | SNX2 (sorting nexin 2) | protein interactions | 6643 | 85 | 23 | 17029 | 2761 |
TCTEX1D2,SNX2,ZNF202,INTS13,GSPT2,KRAS,PAWR,MAN2B1,ERC1,CYB5A,C1orf122,HGS,VPS26B,STAT1,CTPS1,ANP32E,RUVBL2,PDXK,ATP6V1C1,H3F3A,DDB1,VPS29,CDC5L |
| 7.558e-03 | -4.89 | translesion synthesis | biological process | GO:0019985 | 42 | 13 | 17256 | 2622 |
DTL,RPA2,RFC3,PCNA,POLK,RPS27A,USP10,RFC2,MAD2L2,NPLOC4,ISG15,NEXMIF,RPA1 |
| 7.558e-03 | -4.89 | negative regulation of ubiquitin-dependent protein catabolic process | biological process | GO:2000059 | 42 | 13 | 17256 | 2622 |
USP7,PBK,HIPK2,UBXN1,OGT,PML,PSEN1,SENP1,PARK7,PDCL3,RYBP,RPL11,SVIP |
| 7.579e-03 | -4.88 | PARENT_MTOR_SIGNALING_UP | MSigDB lists | PARENT_MTOR_SIGNALING_UP | 537 | 102 | 17377 | 2626 |
EXOC3,NUP188,TSC2,TSC22D3,CAST,MDH2,CHD1L,MOGS,CREBL2,GLUD1,SDHA,GIT2,ZER1,CYHR1,PDK2,THADA,TBC1D22A,ADCY9,MRPS27,HADHB,MAST2,AHCYL1,SLC35C2,CDK12,PCBP2,USP34,PGAP2,PTPN18,EID1,PPIE,ELP4,ATXN1,SLC17A5,ASB13,RAB5B,DHX57,RHEB,GPR137,HSPA4,PEX5,BRWD1,ACYP1,STAT1,DNAJC17,MLYCD,GAS2,OSGEPL1,ATP6V0E1,PDCD4,COMMD10,CTDP1,NADSYN1,RECQL,NDUFS1,CDC40,TM9SF4,DHX9,MYO9B,IP6K2,EZH1,CSNK1A1,NCAPG,SRRT,MFSD10,WDR48,PIP5K1C,FKBP1A,KLHL20,PPIG,TANK,CITED2,TPCN1,IFT46,PHKG2,LYPLA2,NIPSNAP1,EIF5A,PPP3CA,NASP,PRIM2,TSPAN31,NSDHL,OXR1,ZMYM5,TOP3A,UBE4B,FADD,RXRB,GNAS,UPF1,PDCD6,LTBP4,ACOX1,CAPN7,GLG1,CABIN1,MAP3K5,SNRNP70,IDH3B,IFI16,FAF1,SMARCD1 |
| 7.587e-03 | -4.88 | negative regulation of protein metabolic process | biological process | GO:0051248 | 1130 | 201 | 17256 | 2622 |
ZBED3,FGFR1OP,TSC2,NF1,FAM129A,PPP1R15B,XIAP,ENSA,CSNK2A1,YTHDF3,SIRT2,CCNB1,PPP1R16B,RBM4,BIRC2,RIC1,PARK7,PRNP,CDK5,CALM2,CDKN2C,EIF4A3,METTL14,PIK3R2,NOC2L,CRY2,DNMT1,SENP1,RYBP,PLK1,BAK1,AATF,NCK1,PBK,GMFB,EZR,LRP5,BRCA1,SOX4,EIF3A,HHEX,EIF4ENIF1,LIMK1,PRDX5,SOCS4,OGT,CLU,DVL1,ROCK1,CLN3,ARRB2,HDAC2,PDCD4,SVIP,HSPH1,PPP1R2,GMFG,UBXN1,PRKAA1,CIB1,TIA1,EIF2AK4,RGS2,PSEN1,METTL3,VPS25,CNOT3,CFLAR,CD59,TFAP4,FKBP1A,RB1,MEX3C,FBXO7,DAPK1,ARL6IP1,MVP,GNAI2,SOCS5,ZMYND11,OXR1,GTPBP4,GBA,ITM2A,EIF2AK1,FXR1,KDM3A,DAPK3,ISG15,MASTL,TSC1,MBIP,EPRS,SYNCRIP,DUSP3,CSK,QARS,SIAH2,NUP62,CABIN1,CTSA,SNRNP70,TOB1,RNF139,CDKN2A,USP7,PPP1R37,GGNBP2,ASH1L,FOXM1,RPS6KA1,RAF1,CAST,PTTG1,IRF3,LYN,DUSP22,APP,PAIP2,RPL11,TERF2IP,APLP2,MDM2,TNFAIP8,PIN1,PPME1,UCHL5,SOCS6,CDKN1B,TARDBP,GPD1L,STRAP,CTDSP2,PDCL3,CHP1,SNX25,TIMP2,BIRC3,BTG2,CIRBP,DNAJA1,SOCS7,PPP2CA,DNAJC10,IDE,HNRNPR,HIPK2,STK38,CORO1C,GADD45B,PPP5C,SMAD4,PARD3,MIF,BCL2L12,UNK,TRIP12,MECP2,AGO2,AKT1S1,HMG20A,MAD2L2,FBXO5,PTPN2,PTEN,PPP1R8,DUS2,H2AFY,CNOT6L,STAT3,PDPK1,TGFB1,SAMD4B,PPP1R9B,TNFAIP3,PRKDC,ILF3,PRKAR1B,RFFL,MEN1,PICALM,HSPA1B,CNOT9,LEMD2,SH3BP5,UPF1,PLAA,BIRC5,GPS2,PRDX3,PML,GLG1,KHSRP,PPP1R11,NR2F2,PARP10,IGBP1,CPEB2,PURA,HIPK3,IFI16 |
| 7.593e-03 | -4.88 | GSE17721_POLYIC_VS_PAM3CSK4_2H_BMDC_UP | MSigDB lists | GSE17721_POLYIC_VS_PAM3CSK4_2H_BMDC_UP | 181 | 40 | 17377 | 2626 |
COX15,FEZ2,SYS1,TOR3A,DBF4,C5orf30,DHX8,SIKE1,IL21R,FAM8A1,XPR1,ANKRD28,FKBP1A,GATC,ATG3,UCHL5,MAP3K14,DNMT1,MED22,CSTF1,ATP13A1,POLK,SNX2,NEK7,NARF,MRPL43,ASB13,USP36,KIF2A,SERF2,ACOX1,ARNTL,NFIL3,PPM1G,FAM3C,LMBR1,ATF6,GLCCI1,CDK2,RAD51D |
| 7.593e-03 | -4.88 | GSE2405_0H_VS_12H_A_PHAGOCYTOPHILUM_STIM_NEUTROPHIL_DN | MSigDB lists | GSE2405_0H_VS_12H_A_PHAGOCYTOPHILUM_STIM_NEUTROPHIL_DN | 181 | 40 | 17377 | 2626 |
CLSPN,C1orf112,TPX2,RRM1,ZFYVE21,KIF2C,CNTROB,BLM,QSOX2,MOAP1,OIP5,SIVA1,INTS1,DUT,EFCAB11,PRC1,RPAP1,KNTC1,PRIM2,LONRF3,WDHD1,CKAP2L,LRRC1,DCLRE1C,SHCBP1,ARMC8,MASTL,PRIM1,SLCO4A1,OSBPL11,BIRC5,PTER,TRIM32,NDE1,TFDP2,SASS6,E2F2,PDCD2L,ALS2,FAM72A |
| 7.593e-03 | -4.88 | GSE20366_CD103_KLRG1_DP_VS_DN_TREG_DN | MSigDB lists | GSE20366_CD103_KLRG1_DP_VS_DN_TREG_DN | 181 | 40 | 17377 | 2626 |
UBL3,MAGEH1,NQO1,CKLF,GNPDA1,SRGN,ASAH1,NIPA2,DCUN1D4,APH1B,RHBDD1,RTKN,GTPBP3,CDKN2C,INTS7,KIF13B,FUT8,LPCAT1,TMBIM1,ALDH9A1,TCTEX1D2,SNX2,ELL2,NUDT4,SLBP,NLN,IRF5,OPTN,MYO1F,DSN1,BRWD1,DUSP3,UEVLD,MAP4,APPL2,SLC25A19,ADAM9,CAB39,FAM126A,CWC25 |
| 7.593e-03 | -4.88 | GSE27786_CD8_TCELL_VS_NKTCELL_UP | MSigDB lists | GSE27786_CD8_TCELL_VS_NKTCELL_UP | 181 | 40 | 17377 | 2626 |
OTUD5,SNX27,ASH1L,ABCA3,LANCL1,TWF2,FBRS,LIN9,RRN3,CTNNBL1,UTP18,DPYSL2,MBD2,DDA1,PPCDC,ARID4A,SMC4,ABCC5,YTHDC1,IFRD1,FOXK1,EMB,TSPAN31,SLC26A6,USP10,MEN1,KDM1B,MBD3,EIF4G2,SMAP2,ARHGAP15,ANKRD10,HSPB11,HSPBP1,TTC13,CCDC86,NIP7,STK38,DBI,PIAS2 |
| 7.593e-03 | -4.88 | GSE20198_UNTREATED_VS_IL12_TREATED_ACT_CD4_TCELL_UP | MSigDB lists | GSE20198_UNTREATED_VS_IL12_TREATED_ACT_CD4_TCELL_UP | 181 | 40 | 17377 | 2626 |
HECA,GGNBP2,CASP6,PHF23,RAC1,GPR89A,DHX9,MOGS,B4GALT1,JMJD6,CSNK1A1,GLRX3,RCOR3,MAD2L2,TMEM179B,THAP4,EFTUD2,PCYT2,RNASEH2A,ORC3,FTSJ3,ARID4A,SNX25,DDX24,LONRF3,EMB,LACTB,USP22,EAF2,SMC2,ARPC1A,ZFR,IWS1,GEMIN5,CDC27,PARG,H2AFX,RBPJ,PDLIM5,GPR89B |
| 7.593e-03 | -4.88 | GSE22886_NAIVE_CD4_TCELL_VS_48H_ACT_TH1_UP | MSigDB lists | GSE22886_NAIVE_CD4_TCELL_VS_48H_ACT_TH1_UP | 181 | 40 | 17377 | 2626 |
PNISR,SF3B1,HLA-E,MANBA,TSC22D3,ANKH,PTP4A3,BTN3A1,CHKB,CCNL2,PRKD3,PLCL2,SMARCE1,TPCN1,ZC3H3,CAMK2G,CARS2,USP34,NAGPA,PBXIP1,BTG2,ZMYM5,ZBED5,RPS24,SRSF5,ICAM2,PRMT2,RPS9,BSDC1,RBM38,PLEKHF2,TSC1,TMEM127,ZNF862,ATP1A1,RPL32,RNF38,RPLP1,TMEM159,FAU |
| 7.593e-03 | -4.88 | GSE11961_FOLLICULAR_BCELL_VS_MEMORY_BCELL_DAY7_UP | MSigDB lists | GSE11961_FOLLICULAR_BCELL_VS_MEMORY_BCELL_DAY7_UP | 181 | 40 | 17377 | 2626 |
DDX58,TMEM184B,HLA-E,TOR1AIP1,PTTG1,AP3M2,MYH9,SLC4A2,CHKB,SNN,EPHX2,PA2G4,ZCCHC2,PPP1R12C,BRI3,ORAI1,ARHGEF2,SGCB,TRIM14,S100A6,SGCE,TRAFD1,ERLIN1,SLC25A22,EDF1,EAF2,MARK2,IRF5,ALKBH6,KEAP1,POLR2J,RPS14,DCK,NDUFA11,PML,ZSWIM3,LONP2,SMARCD1,RNF114,ATXN7L2 |
| 7.600e-03 | -4.88 | CREB1 (cAMP responsive element binding protein 1) | protein interactions | 1385 | 159 | 38 | 17029 | 2761 |
RECQL,ATXN3,SUZ12,RPS6KA1,MECP2,TRIM11,SMARCA4,NIT2,UBE2I,PRKACA,MAPK14,ZNF92,CREM,FAM192A,ZBTB21,CREB1,ATF2,STAT3,CARM1,DEAF1,NFATC2,BRCA1,EDF1,RAB1A,POLR2A,CCDC6,PFDN4,GPS2,CHD3,ZHX1,NFIL3,MIA2,ZNF436,ATF6,YY1,RBBP4,HIPK3,HDAC2 |
| 7.606e-03 | -4.88 | REACTOME_DOWNSTREAM_SIGNALING_OF_ACTIVATED_FGFR | MSigDB lists | REACTOME_DOWNSTREAM_SIGNALING_OF_ACTIVATED_FGFR | 96 | 24 | 17377 | 2626 |
PDPK1,NRAS,TSC2,AKT2,RAF1,PRKAR1B,KRAS,AKT1S1,PRKACA,FOXO3,MAP2K2,MAPK3,CALM2,FGFR3,MDM2,SHC1,PTEN,ADCY9,CDKN1B,CREB1,MAPK1,HRAS,ADCY7,MLST8 |
| 7.619e-03 | -4.88 | double-stranded DNA binding | molecular function | GO:0003690 | 859 | 158 | 17224 | 2647 |
RORB,IER2,MAX,H2AFZ,CXXC1,KIF2C,MYEF2,PARK7,MBD4,CREM,USF1,PCNA,GLIS2,ZNF639,ETV6,XRCC2,CRY2,SMARCE1,MYBL1,CDC5L,SP3,TDP1,DEAF1,KLF10,BAZ2A,GABPA,RAD51AP1,EAF2,MCM2,SOX4,UBTF,HHEX,SMAD2,E2F4,PQBP1,ACTB,TFDP2,SMAD1,E2F2,HDAC2,DDX58,DHX9,CTCF,MEF2A,THRAP3,TFAP4,MLX,NFATC3,MED8,KLF16,MCM5,MBD2,SSBP3,ZNF746,MSH2,ZNF335,YBX1,AFF1,TNRC18,TERF2,ETV3,FOXK1,ZMYND11,MTA2,LDB1,MYBL2,ELK1,KDM3A,SLTM,XRCC5,RXRB,ETS2,NFIL3,NLRC5,CEBPG,TBPL1,RUVBL2,YY1,RBBP4,TCF12,MBD1,IVNS1ABP,FOXM1,SUZ12,PMS2,SMARCA4,IRF3,SAFB2,MXD1,NRF1,RRN3,MTA1,AKAP8,GMEB1,TARDBP,ATF2,CGGBP1,POU2AF1,KDM3B,MND1,CGAS,KAT7,E2F3,WBP2,PCGF6,NFATC2,MEF2D,MBD3,VEZF1,RAD51C,SAFB,MAFK,STAT6,ARNTL,STAT1,RBMS1,ATF6,XRCC3,BEND3,H3F3A,AKNA,SMAD4,RAD51D,POU3F2,MCM10,MTERF1,MECP2,TCF3,KLF13,NKRF,ETS1,IRF4,SUV39H2,PRDM4,H2AFY,CARF,ORC3,CREB1,STAT3,MSH6,NCOA2,ZFP64,PSPC1,ZNF202,PRKDC,MEN1,KLF6,TFEB,TFE3,NEIL3,PITX1,TFDP1,HMGB2,RBPJ,USF2,TERF1,PURA,IFI16 |
| 7.621e-03 | -4.88 | Aortic root size(PMID:21223598) | GWAS genes | Aortic root size(PMID:21223598) | 4 | 3 | 2388 | 307 |
CRCP,KCTD7,GOT2 |
| 7.622e-03 | -4.88 | GSE11961_FOLLICULAR_BCELL_VS_GERMINAL_CENTER_BCELL_DAY40_UP | MSigDB lists | GSE11961_FOLLICULAR_BCELL_VS_GERMINAL_CENTER_BCELL_DAY40_UP | 192 | 42 | 17377 | 2626 |
PRKAB1,ASH1L,DNMT3A,PNISR,KRBA1,DAP,LANCL1,CNTROB,MXD4,RGS2,C2orf68,EEF2K,SLC25A36,XPA,ATP6V0A2,KIFAP3,PIK3IP1,ZRANB1,GNAI2,GM2A,CAMK2G,SCFD2,HEBP2,ITM2A,ANAPC2,PACS1,KRAS,SOX4,HAGH,SGSH,JAK1,GPS2,ACOX1,STK38,HAGHL,RNASEL,LTA4H,USF2,PDCD4,ESYT2,SNAPIN,S100PBP |
| 7.622e-03 | -4.88 | GSE37534_UNTREATED_VS_GW1929_TREATED_CD4_TCELL_PPARG1_AND_FOXP3_TRASDUCED_UP | MSigDB lists | GSE37534_UNTREATED_VS_GW1929_TREATED_CD4_TCELL_PPARG1_AND_FOXP3_TRASDUCED_UP | 192 | 42 | 17377 | 2626 |
BCCIP,AP3M2,ZNF107,CREBL2,GYG1,CCDC28A,SAP130,HOMER1,SLC1A4,MBD2,ZCCHC2,BUD31,DAPK1,FBXL7,DNAL4,EBAG9,ERCC1,IFRD1,CSRP1,TNFAIP3,ZNF574,OGFR,LY6E,RHBDF2,EIF3K,HLA-B,VEZF1,SLCO4A1,TRIM26,MID1IP1,HSPBP1,UAP1,DUSP3,STX18,CEBPG,PPP1R11,RGL1,EHD4,PGAM1,TSPAN5,CSNK1D,RAB3IL1 |
| 7.622e-03 | -4.88 | GSE17721_LPS_VS_GARDIQUIMOD_8H_BMDC_DN | MSigDB lists | GSE17721_LPS_VS_GARDIQUIMOD_8H_BMDC_DN | 192 | 42 | 17377 | 2626 |
TMEM106C,SEPHS2,BCCIP,GMFG,DYNLL1,HNRNPUL2,MAPK14,BECN1,GFM2,PNO1,PRNP,DDX56,PRKD3,NOL11,KLHL20,ATP2A2,HDAC7,PPCDC,DAPK1,ACSL5,SLC39A9,CCT2,EIF3L,FAM118B,TUFM,SOX4,MCFD2,NDRG3,STK17B,MAK16,TARS,MAPK3,HHEX,PON2,ADAM9,ATP6V0C,ACADM,LTA4H,HRAS,MRPL3,ZNF146,PDF |
| 7.622e-03 | -4.88 | GSE37301_MULTIPOTENT_PROGENITOR_VS_GRAN_MONO_PROGENITOR_DN | MSigDB lists | GSE37301_MULTIPOTENT_PROGENITOR_VS_GRAN_MONO_PROGENITOR_DN | 192 | 42 | 17377 | 2626 |
UBL3,NOP2,GADD45G,TRIO,TAP1,PAWR,AGFG1,PSEN1,LYN,ABHD16A,PHC2,SLC31A1,CLIC4,IL6ST,PPA1,CARM1,IFRD1,LARS,TRAFD1,BIRC3,NCK1,TOR1AIP2,PACS1,MAP4K3,CDC23,OGFR,KLF6,PSMB9,MARK2,SLTM,POLR2A,ISG15,PI4K2A,CSK,TAB2,TFDP1,STAT1,PML,CEBPG,ADAM9,LY75,ADAM23 |
| 7.622e-03 | -4.88 | GSE26030_UNSTIM_VS_RESTIM_TH1_DAY15_POST_POLARIZATION_DN | MSigDB lists | GSE26030_UNSTIM_VS_RESTIM_TH1_DAY15_POST_POLARIZATION_DN | 192 | 42 | 17377 | 2626 |
B4GALT5,CCM2,TKT,SLC39A13,RRM1,SMC6,JMJD6,IRF3,SLC29A1,ETS1,SAFB2,PIP4K2A,QSOX2,NFATC3,NUP210,THAP4,RIMS3,ALDH18A1,CARM1,ALDH9A1,ABCC5,MAPRE2,RHOA,PBXIP1,ANKRD33B,PIP4K2C,DNAJC9,KRAS,CYFIP2,ZFAND5,CYB5A,CDKN2AIPNL,STK38,E2F4,LY75,YWHAZ,CENPT,TFDP2,BRD9,ATMIN,DEF6,AAAS |
| 7.622e-03 | -4.88 | GSE26343_WT_VS_NFAT5_KO_MACROPHAGE_LPS_STIM_UP | MSigDB lists | GSE26343_WT_VS_NFAT5_KO_MACROPHAGE_LPS_STIM_UP | 192 | 42 | 17377 | 2626 |
UGP2,PHF23,ZDHHC8,DAP,MUM1,CERK,SIKE1,USP48,RGS2,GOLM1,USF1,SOCS6,DDX31,ZNF710,GPD1L,SEPT9,POLK,ZNF202,EMB,TLK1,FRAT2,SLC25A22,EIF2AK1,NFATC2,USP22,MEF2D,CBFB,CLNS1A,RPA1,PTPRF,FBXO21,ALDH3B1,HHEX,OSBPL11,LPCAT4,CTSA,ZFP90,SCARB1,RNASEL,DMWD,AP2S1,PDCD4 |
| 7.622e-03 | -4.88 | GSE32164_RESTING_DIFFERENTIATED_VS_ALTERNATIVELY_ACT_M2_MACROPHAGE_DN | MSigDB lists | GSE32164_RESTING_DIFFERENTIATED_VS_ALTERNATIVELY_ACT_M2_MACROPHAGE_DN | 192 | 42 | 17377 | 2626 |
SEPHS2,UBE2D3,RAB14,PPP1R15B,TRIM11,SRGN,CDC42SE2,CDIPT,RGS2,CRLF3,ETS1,BCAP31,DNAJB9,SLC25A36,RPN1,RNFT1,SLC44A1,AKAP8,EI24,MDFIC,F2R,VOPP1,CYFIP1,TRAFD1,FAM49B,DENND4C,CUL3,WIPF1,PTTG1IP,C9orf40,EIF4G2,PSMB9,IRF5,HLA-B,AHNAK,FNTA,RAB24,SAFB,ARNTL,ITGB1,EYA2,SMNDC1 |
| 7.647e-03 | -4.87 | GTACTGT,MIR-101 | MSigDB lists | GTACTGT,MIR-101 | 242 | 51 | 17377 | 2626 |
UBE2D3,ZNF207,DNMT3A,EYA1,NACA,PRKAA1,RRM1,CTCF,UBE2Q1,AP3S1,BZW2,APP,TMEM161B,MXD1,FZD6,RGS1,PIP5K1C,DLG5,SUB1,ZNF746,ZCCHC2,TERF2,ABCC5,SOCS5,SRPK2,MOB4,CLCN3,PHF20L1,MLEC,BAZ2A,C16orf72,KAT7,HNRNPF,ATXN1,ARID1A,CADM1,BICD2,SRSF5,CBFA2T2,RAB1A,DOT1L,RXRB,ANKZF1,OGT,SEL1L,RNF38,PIEZO1,NUDT11,CPEB2,PRPF4B,SMARCD1 |
| 7.652e-03 | -4.87 | CEP76 (centrosomal protein 76) | protein interactions | 79959 | 154 | 37 | 17029 | 2761 |
RPS15,MRPS26,MOGS,CSNK2A1,PPP3CB,SNRPD3,CUTC,MYL6B,RPL23A,RAD23A,CCNK,CEP104,CCP110,RPL17,CENPJ,PIN1,MRPS27,SMARCE1,PRPF19,SPTAN1,PPP3CA,RPL38,DCTD,UHRF1BP1,MBD3,RFC2,RPS9,CSNK1G1,RPS14,CEP55,LRPPRC,KLHDC4,RBBP4,SINHCAF,COIL,TUBB,ZBTB24 |
| 7.656e-03 | -4.87 | C1orf94 (chromosome 1 open reading frame 94) | protein interactions | 84970 | 71 | 20 | 17029 | 2761 |
UBQLN4,USO1,MAGED1,HNRNPF,ATXN1,BOLA1,GORASP2,DAZAP2,SMAP2,OIP5,RBM47,PITX1,C1orf109,TNPO2,RPAP1,MVP,GCC1,RAD51D,CARM1,BYSL |
| 7.656e-03 | -4.87 | PRRC2A (proline rich coiled-coil 2A) | protein interactions | 7916 | 71 | 20 | 17029 | 2761 |
IMMT,CYLD,EWSR1,CUL3,DDX20,ATXN1,GORASP2,PRMT2,LUC7L,MAD2L2,RPA1,CAND1,WWP2,RPA2,QARS,TARDBP,SNRNP70,HNRNPM,IFI16,SRPK2 |
| 7.656e-03 | -4.87 | TERT (telomerase reverse transcriptase) | protein interactions | 7015 | 71 | 20 | 17029 | 2761 |
UBE2D3,PHF20L1,PBK,DYNLL1,CIB1,TIMM21,ATP5F1B,FOXO3,XRCC5,MDM2,HSPA4,U2SURP,PML,YWHAZ,RUVBL2,PTGES3,TERF1,PABPC1,POT1,DDB1 |
| 7.656e-03 | -4.87 | PYM1 (PYM homolog 1, exon junction complex associated factor) | protein interactions | 84305 | 71 | 20 | 17029 | 2761 |
RPS2,RBM8A,RPS10,RNPS1,RPS24,KCMF1,RPS9,APP,ISG15,PNO1,AKAP1,PRNP,CDKN2C,RPS14,TARDBP,FAU,RPS26,POT1,DCAF5,BYSL |
| 7.656e-03 | -4.87 | UHRF1 (ubiquitin like with PHD and ring finger domains 1) | protein interactions | 29128 | 71 | 20 | 17029 | 2761 |
UBE2D3,USP7,ERCC1,DNMT3A,SUZ12,CUL1,UHRF1BP1,NFATC2,MPG,PRKACA,TRIM28,MBD4,RB1,PCNA,AHSA1,UHRF2,PML,USP11,DNMT1,MRM3 |
| 7.656e-03 | -4.87 | CDK11A (cyclin dependent kinase 11A) | protein interactions | 728642 | 71 | 20 | 17029 | 2761 |
CCT2,IVNS1ABP,KAT7,RNPS1,CSNK2A1,B4GALT1,CCNL2,ZNF267,MCM2,CDK11B,SUPT16H,PSMD1,RBM25,PIN1,UHRF2,CTR9,FKBP5,KPNA2,CDKN2A,CDC37 |
| 7.658e-03 | -4.87 | negative regulation of RNA biosynthetic process | biological process | GO:1902679 | 1216 | 215 | 17256 | 2622 |
RORB,TXN,ZNF496,MAX,H2AFZ,KDM4A,TSC22D3,TRIM11,SIRT2,UBE2I,CREM,CDK5,PA2G4,CIPC,GLIS2,ZNF639,JAZF1,ETV6,NOC2L,CRY2,FNIP2,SMARCE1,DNMT1,ARID4A,CCAR1,RYBP,PTPRK,PLK1,PLK3,SP3,DEAF1,KLF10,PBXIP1,NCK1,BAZ2A,GABPA,VHL,EHMT1,RIOX2,EZR,DDX20,AURKB,BRCA1,DOT1L,PAF1,BRMS1,HHEX,SMAD2,TONSL,RPS27A,RPS14,AXIN1,PRDX5,ZNF268,TFDP2,BEND6,HDAC2,PDCD4,ZNF564,UBE2D3,PHB2,CENPF,CTCF,MEF2A,DNAJB1,PSEN1,CDC73,LYAR,TFAP4,RB1,MLX,NFATC3,KLF16,MBD2,HDAC7,ZNF746,PHF14,CTR9,TIMELESS,MDFIC,YBX1,MCPH1,TNRC18,ZNF189,ETV3,FOXK1,CREG1,ZMYND11,CIC,MTA2,LDB1,BCLAF1,RTF1,ARID1A,CBFA2T2,ZNF174,PHF6,XRCC5,PFDN5,ETS2,QARS,NFIL3,SIAH2,ZFP90,RUVBL2,YY1,CDK2,TOB1,N4BP2L2,CDKN2A,MBD1,ZNF296,DNMT3A,MPHOSPH8,FOXM1,SUZ12,UBR2,MAGED1,WDTC1,SMARCA4,IRF3,DUSP22,RCOR3,MXD1,HNRNPA2B1,SPINDOC,SAP130,ZBTB21,MDM2,SHC1,SP100,MTA1,CDKN1B,RBM15,ATF2,STRAP,CGGBP1,RLIM,MOSPD1,SAP30,FAM172A,ZNF500,ERF,EID1,BTG2,DRAP1,PCGF6,CUL3,ATXN1,NFATC2,H2AFV,MBD3,TRIM28,CHCHD3,ZNF282,RBL1,MAFK,HIPK2,STAT6,ARNTL,H2AFX,DNAJC17,STAT1,BEND3,H3F3A,SMAD4,LRP8,CBX4,NCOR2,DEPDC1,DAP,MECP2,TCF3,ARID5A,PAWR,NKRF,MXD4,FOXO3,HMG20A,MAD2L2,WWP2,PTPN2,SUV39H2,KMT5A,H2AFY,BRD7,CITED2,CREB1,STAT3,NCOA2,RBM15B,TSHZ1,TGFB1,PSPC1,ZNF202,BTAF1,ILF3,RCOR1,PRMT2,MEN1,ZP3,CBX3,BIRC5,GPS2,ZHX1,PITX1,E2F1,PML,HMGB2,DDX5,RBPJ,NR2F2,IGBP1,PURA,IFI16 |
| 7.676e-03 | -4.87 | CDK-mediated phosphorylation and removal of Cdc6 | REACTOME pathways | R-HSA-69017 | 52 | 16 | 10287 | 1696 |
PSMD2,PSMD1,PSMA6,PSMA8,RPS27A,PSMD8,PSMD3,PSMB7,PSMA1,CDC6,CDK2,PSMB9,PSMD9,PSMC1,PSMB3,PSMC4 |
| 7.677e-03 | -4.87 | - | gene3d domains | 1.25.40.180 | 16 | 7 | 8148 | 1295 |
UPF2,MIF4GD,EIF5,EIF4G2,BZW2,PAIP1,PDCD4 |
| 7.678e-03 | -4.87 | SIG_PIP3_SIGNALING_IN_CARDIAC_MYOCTES | MSigDB lists | SIG_PIP3_SIGNALING_IN_CARDIAC_MYOCTES | 66 | 18 | 17377 | 2626 |
PDPK1,TSC1,SHC1,TSC2,CDC42,PTEN,AKT2,RPS6KA1,CDKN1B,YWHAZ,BCL2L1,CREB1,CDK2,YWHAH,FOXO3,PARD3,CDKN2A,EBP |
| 7.678e-03 | -4.87 | GO_SMALL_RIBOSOMAL_SUBUNIT | MSigDB lists | GO_SMALL_RIBOSOMAL_SUBUNIT | 66 | 18 | 17377 | 2626 |
RPS15,RPS2,MRPL42,MRPS2,MRPS15,RPS10,MRPS26,RPS24,MRPS14,RPS9,RPSA,MCTS1,DAP3,RPS27A,RPS14,EIF2D,FAU,RPS26 |
| 7.678e-03 | -4.87 | GO_REGULATION_OF_CELLULAR_AMINO_ACID_METABOLIC_PROCESS | MSigDB lists | GO_REGULATION_OF_CELLULAR_AMINO_ACID_METABOLIC_PROCESS | 66 | 18 | 17377 | 2626 |
NQO1,PSMA8,PSMB7,PSMA1,ODC1,PSMB9,PSMD9,PARK7,PSMB3,PSMC4,PSMD2,PSMA6,PSMD1,PSMD3,PSMD8,OAZ2,OAZ1,PSMC1 |
| 7.681e-03 | -4.87 | human chr16q22.1 | chromosome location | human chr16q22.1 | 112 | 21 | 26185 | 2809 |
DDX28,EXOSC6,NQO1,CTCF,NUTF2,CBFB,WWP2,NFATC3,NIP7,E2F4,DUS2,PRMT7,ZFP90,ST3GAL2,CENPT,VPS4A,UTP4,ATP6V0D1,DYNC1LI2,PDF,TERF2 |
| 7.682e-03 | -4.87 | TPR_8 | pfam domains | PF13181 | 57 | 16 | 17054 | 2545 |
RPAP3,SRP72,NASP,ST13,XAB2,CDC23,PEX5,TTC13,CDC27,TONSL,ZC3H7B,OGT,CTR9,ANAPC7,FKBP5,TTC17 |
| 7.692e-03 | -4.87 | GSE40274_CTRL_VS_GATA1_TRANSDUCED_ACTIVATED_CD4_TCELL_DN | MSigDB lists | GSE40274_CTRL_VS_GATA1_TRANSDUCED_ACTIVATED_CD4_TCELL_DN | 154 | 35 | 17377 | 2626 |
RBM8A,ARID5A,NUP54,FAM76A,PMF1,XPNPEP3,S1PR2,IL21R,MXD1,MEX3C,EIF4A3,ORAI1,PIK3IP1,CNOT6L,PLK3,CSRP1,ELL2,ERF,EZR,USP22,KLF6,SNRPA,EIF3A,NMT2,RHEB,IWS1,KIF18A,KPNA4,MAFK,SIAH2,FAM126A,KLHDC4,NRBP1,ATMIN,CBX4 |
| 7.692e-03 | -4.87 | GSE34156_NOD2_LIGAND_VS_NOD2_AND_TLR1_TLR2_LIGAND_24H_TREATED_MONOCYTE_DN | MSigDB lists | GSE34156_NOD2_LIGAND_VS_NOD2_AND_TLR1_TLR2_LIGAND_24H_TREATED_MONOCYTE_DN | 154 | 35 | 17377 | 2626 |
MAGEH1,CDS2,SARNP,GXYLT1,NDUFB6,RPLP2,UBE2Z,COX4I1,SECISBP2,FAM136A,RAB11A,ADD3,NDUFB4,HUWE1,IL6ST,RBM34,ZNHIT6,BTF3L4,NSFL1C,TTC3,FAM86C1,CNPY3,MSH6,ABCC1,RBX1,ZBED5,PPWD1,POLG2,EIF3H,RPSA,MBIP,RAD51C,PRDX3,PPP6R3,ANAPC4 |
| 7.692e-03 | -4.87 | GSE37301_HEMATOPOIETIC_STEM_CELL_VS_LYMPHOID_PRIMED_MPP_DN | MSigDB lists | GSE37301_HEMATOPOIETIC_STEM_CELL_VS_LYMPHOID_PRIMED_MPP_DN | 154 | 35 | 17377 | 2626 |
SRM,HSPH1,NQO1,KDM4A,WDYHV1,NUP54,CHIC2,CYCS,DNAJB1,FKBP2,ZADH2,PTPN2,RAB21,PTPN11,H2AFY,MRPL21,MVP,PGAP2,COPS8,CCT2,EZR,SYVN1,KRTCAP2,PICALM,UTP20,MAGT1,UEVLD,TWSG1,CERS6,PSMD3,STK38,ITGB1,ZRANB2,BEND6,SLC25A33 |
| 7.698e-03 | -4.87 | WH-like_DNA-bd_sf | interpro domains | IPR036388 | 233 | 49 | 18492 | 2768 |
RECQL,PARP12,DEPDC1,ARID2,FOXM1,SHPRH,CUL1,IRF3,LACTB2,BLM,ETS1,FOXO3,VPS25,GTF2F1,DDRGK1,RPA2,PA2G4,IRF4,ETV6,FOXN2,PIKFYVE,DVL2,HP1BP3,ETV3,FOXK1,ERF,GABPA,KAT7,CUL3,RPS10,E2F3,TIGD5,ANAPC2,CDC6,PLEC,ELK1,KDM1B,IRF5,EIF3K,ETS2,E2F4,TFDP1,E2F1,CENPBD1,DVL1,TFDP2,E2F2,ZC3HAV1,TIGD2 |
| 7.706e-03 | -4.87 | exon-exon junction complex | cellular component | GO:0035145 | 21 | 8 | 18223 | 2701 |
UPF1,R3HCC1L,EIF4A3,RBM8A,RNPS1,UPF2,THRAP3,SRSF1 |
| 7.706e-03 | -4.87 | anaphase-promoting complex | cellular component | GO:0005680 | 21 | 8 | 18223 | 2701 |
CDC16,CDC27,ANAPC7,ANAPC2,CDC23,UBE2C,ANAPC4,MAD2L2 |
| 7.723e-03 | -4.86 | anion binding | molecular function | GO:0043168 | 2747 | 465 | 17224 | 2647 |
RAB14,ABCC10,TAP1,DHX8,GLUD1,UBE2I,OAT,EEF2K,KIFC1,CDK5,NEK6,GSDMB,CYB5RL,RAB4A,ATP13A3,PDS5B,DNM2,UPRT,SUCLG2,CRY2,MAST2,PLCL2,PLK3,RHOBTB3,NRAS,AKT2,PBK,KIF15,MKI67,DDX20,SMC2,AURKB,MCM2,RFC2,RAB22A,RAB2B,ARF4,PLEKHF2,KRIT1,STOML2,MAP3K4,MKNK1,KIF18B,LIMK1,MYO18A,OGT,DHTKD1,RNASEL,LONP2,PFKP,ANXA11,DDX42,DDX58,HSPH1,RECQL,CHTF18,RHOC,TRIO,GSPT2,PRKAA1,DHX9,RRM1,RAB23,CERK,KIF23,TOP2B,EIF2AK4,PDXDC1,RTKN,DDX56,CEP104,SMC3,SNX18,MCM5,EFTUD2,CTPS1,MSH2,DAPK1,RTCB,PIKFYVE,GNAI2,SYTL3,PHKG2,UBE2QL1,CARS2,DDX28,COQ8A,MAPKAPK3,DHX29,NOA1,PGS1,TYW1,GTPBP4,PIP4K2C,SEPT8,RIT1,PKM,ABCF1,MAP2K2,CCT8,RHOB,PI4K2A,XRCC5,ADSS,PTPRF,EPRS,MTHFD2,NSF,CSK,CSNK1G1,DCK,QARS,ACLY,ARAP1,WIPI2,MAP3K5,RUFY3,CDK2,NRBP1,ACSF2,SNX14,ZC3HAV1,EGLN1,ZNF207,RHOG,KARS,ABCA3,TP53RK,RAB11B,RPS6KA1,UBR2,RAF1,CHD1L,KIAA0232,RAC1,ACTR3,OLA1,TPX2,MYH9,EFL1,PRKACA,CPNE3,SDHA,CBWD5,APP,FLAD1,DECR1,RAB21,PRKD3,APLP2,ATP2A2,SHC1,RALB,UBA5,ADCY9,ZCCHC2,CLCN6,NSFL1C,SEPT11,TAP2,AQR,ARL5A,CDK12,ADCY7,SNX8,CPNE1,CCT2,ULK3,ATP13A1,MAP4K4,TAOK1,PFKFB3,GALK2,PKMYT1,DNAJA1,RAB1A,MAT2A,DHX57,DDX17,KIF2A,RAD51C,HSPA4,JAK1,RAB24,GUCY1B1,HIPK2,CBWD1,PDXK,PPP5C,CSNK1D,TUBB,DYNC1LI2,RHEBL1,PRPF4B,POLQ,GALK1,ANXA6,SESTD1,TWNK,IP6K2,ATP5F1B,LANCL1,BLM,PMVK,IFT27,RAB11A,PIP5K1C,SRXN1,GATC,CBWD2,ARF5,ANXA5,TTLL12,ST8SIA2,MAP3K14,UBE2M,MSH6,SMC4,PDPK1,TK1,DDX24,GUK1,DENND1B,NEK7,BMS1,KCNQ1,RHOT1,DDX39A,GUF1,KIF11,MARK2,PICALM,MYO1F,SLC19A1,GNA12,KIF18A,TTLL4,ACOX1,DBI,MAPK6,ASNA1,DDX5,PSAP,WDR45B,ESYT2,DDX52,ADA2,DDX47,UBE2E2,AGRN,ST13,NF1,YTHDC2,SNX15,MCCC1,CSNK2A1,UBE2Q1,UBE2Z,ABCB10,KIF2C,SIRT2,RUFY1,MAPK14,PAPOLA,ABL2,RAB8A,RAP1A,CDC42,GOT2,EIF4A3,RAB35,TRMU,XRCC2,KIF22,RP2,EIF5,ABCC5,SRPK2,PLK1,LARS,SNRNP200,SEPT9,HARS,TLK1,CDC6,PITPNB,ESYT1,RAB5B,LSG1,STK17B,RHEB,DHX15,DPYSL3,EPB41,SEPT1,CHD3,IARS2,ACBD4,BAZ1B,QRSL1,ACTB,STK11,CHEK2,VPS4A,ROCK1,PSMC1,C2CD5,SEPHS2,UBE2D3,RACGAP1,CDK13,RAB6A,THRAP3,RAPGEF6,CHKA,UBE2Q2,KIF13B,GLE1,ACAD8,ALDH18A1,N4BP2,CSNK1G3,ABCC1,NTPCR,AACS,NQO2,ACSL3,KRAS,EIF2AK1,MAP4K3,UBE4B,SEPT7,DAPK3,BBS12,MASTL,PSMC4,GNAS,PRPS2,NLRC5,NUP62,PITPNA,RUVBL2,ATP5F1A,EHD4,MYO9A,UNC13C,SNX27,CHMP2A,MMACHC,UCK2,PMS2,SMARCA4,RRAGC,UCK1,CHKB,ORC1,ATP6V1B2,LYN,TWF2,CHD1,MIEF1,FARSA,PDK2,PSMA6,IARS,DUS4L,SAR1A,NVL,KIF14,CYB5R1,SAP30L,SCYL3,SNX25,ACSL5,CLCN3,RPL29,CGAS,RAB7A,OGDH,KDM1B,ARL5B,GFER,RAD54B,DAP3,IDE,ATP1A1,DUS3L,DHX16,CLK3,FASTK,TULP3,STK38,XRCC3,SCARB1,SMURF1,MAPK1,SMAD4,ABCA1,PARD3,ZNF146,RAD51D,NADSYN1,KIF3B,GOLPH3L,SHPRH,TOR3A,SCYL1,GNE,SMC6,ARFIP2,ARF1,MYO9B,CDK11B,CSNK1A1,SCYL2,PIP4K2A,GFM2,XPR1,WRNIP1,KIF5B,GTPBP3,FGFR3,STARD9,NDUFV1,GART,GRK2,DUS2,ABCD1,DDX31,CAMK2G,MICAL3,MYO5A,RNLS,CSNK1G2,RHOA,SNX2,PRKDC,HELB,BTAF1,ATP2C1,ABCF2,TUFM,PRKAR1B,NADK2,PNPLA8,RHOT2,CDK11A,TARS,MAPK3,MFN2,DDX23,HSPA1B,RAB18,NEK1,UPF1,ATAD2,OSBPL8,ACADM,NR2F2,PLOD3,RPS6KC1,UBE2C,HRAS,HIPK3,TYW1B |
| 7.723e-03 | -4.86 | ELOC (elongin C) | protein interactions | 6921 | 129 | 32 | 17029 | 2761 |
CORO7,RBX1,VHL,ELOA,LAGE3,CUL3,JTB,ADRB2,PCGF1,ASB13,SPR,EIF1B,CBFB,EXT2,ARID1B,LRRC14,ZER1,MED8,FBXO7,SOCS4,SOCS6,FEM1B,CTR9,CHMP4B,RBM3,FUS,COPS6,SAT2,NRBP1,ASB6,SPSB3,IFI16 |
| 7.737e-03 | -4.86 | regulation of protein serine/threonine kinase activity | biological process | GO:0071900 | 511 | 98 | 17256 | 2622 |
BCCIP,CCNC,KARS,TRAF7,MAP3K7CL,NF1,RAF1,MAGED1,CCNL2,CCNB1,S1PR2,DAZAP2,LYN,DUSP22,MAPK14,CALM2,CDKN2C,CRKL,RAP1A,SHC1,RALB,CDKN1B,F2R,CDK12,DVL2,MLST8,CDC37,PLK1,COPS8,PSRC1,MAP4K4,TAOK1,CDC6,UBE2V1,LRP5,PKMYT1,DNAJA1,MAP3K4,PPP2CA,HHEX,RPS27A,TAB2,STK38,AXIN1,GADD45B,CAB39,ADAM9,STK11,MAPK1,PDCD4,MIF,ZFP91,PRKAA1,GADD45G,LAMTOR3,CIB1,RGS2,BLM,PSEN1,CCNK,TFAP4,PDCD10,PTEN,FBXO7,PTPN11,H2AFY,MDFIC,MAP3K14,GNAI2,TGFB1,TELO2,ADAM17,RHOA,TNFAIP3,MAPKAPK3,GTPBP4,GBA,PRKAR1B,KRAS,MAP4K3,ADRB2,MEN1,MAP2K2,MAPK3,MBIP,HGS,GPS2,DUSP3,CSK,NUP62,PKD2,NR2F2,MAP3K5,CD81,HRAS,HIPK3,CDKN2A,ALS2 |
| 7.750e-03 | -4.86 | MPP6 (membrane palmitoylated protein 6) | protein interactions | 51678 | 44 | 14 | 17029 | 2761 |
FTL,NAT9,EXOSC6,EXOSC7,AATF,NSUN2,DNM2,SMARCA4,EXOSC9,SLC20A1,PARN,EIF3G,ABCA1,OPTN |
| 7.750e-03 | -4.86 | RAB6A (RAB6A, member RAS oncogene family) | protein interactions | 5870 | 44 | 14 | 17029 | 2761 |
RPA2,GOLGA4,GOLGA2,RAB11B,DNAAF2,RAB7A,ARF1,BICD2,FKBP2,RNF26,RAB1A,ERC1,RPA1,DCTN1 |
| 7.750e-03 | -4.86 | YARS2 (tyrosyl-tRNA synthetase 2) | protein interactions | 51067 | 44 | 14 | 17029 | 2761 |
MRPL50,DDX28,RBM42,MRPL39,RBMX,MRPL12,CIRBP,CUL3,RBM3,HNRNPDL,LYRM2,ZC3H3,DDRGK1,CAND1 |
| 7.750e-03 | -4.86 | IRF7 (interferon regulatory factor 7) | protein interactions | 3665 | 44 | 14 | 17029 | 2761 |
DEAF1,GCLM,SMAD2,TNFAIP3,KAT2A,SUMO2,TANK,LTN1,TICAM1,IRF3,MAVS,SMAD4,TRIM28,FADD |
| 7.750e-03 | -4.86 | CEP85 (centrosomal protein 85) | protein interactions | 64793 | 44 | 14 | 17029 | 2761 |
EWSR1,PSMA6,PCM1,CCDC14,WDYHV1,CENPJ,ODF2,PTTG1,CEP63,CNTROB,KCMF1,TERF1,EYA2,MASTL |
| 7.750e-03 | -4.86 | PDE4D (phosphodiesterase 4D) | protein interactions | 5144 | 44 | 14 | 17029 | 2761 |
PPP3CA,MDM2,PPP3R1,PPP3CB,HDGFL2,CDK2,ARRB2,CSNK1A1,LYN,MAPK1,PRKACA,COIL,APP,SPTAN1 |
| 7.750e-03 | -4.86 | DFFA (DNA fragmentation factor subunit alpha) | protein interactions | 1676 | 44 | 14 | 17029 | 2761 |
MAT2B,BAK1,EWSR1,TMBIM4,TSPYL4,ATG3,STRN4,CTPS1,YWHAZ,PPP5C,EIF5,BZW2,MAT2A,TUBB |
| 7.750e-03 | -4.86 | chr1p34 | MSigDB lists | chr1p34 | 138 | 32 | 17377 | 2626 |
HIVEP3,MMACHC,PPCS,CLSPN,KDM4A,GPBP1L1,UROD,CDCA8,RRAGC,KIF2C,THRAP3,PHC2,TMEM69,MED8,YBX1,MAST2,ERI3,NSUN4,AMPD2,PLK3,NASP,HPDL,MAP7D1,PEF1,NCDN,PRDX1,C1orf122,PTPRF,C1orf109,UQCRH,NDUFS5,LRP8 |
| 7.754e-03 | -4.86 | ZF_UBP | prosite domains | PS50271 | 14 | 6 | 12060 | 1670 |
BRAP,USP39,USP20,USP22,USP5,USP13 |
| 7.770e-03 | -4.86 | GO_REGULATION_OF_DEFENSE_RESPONSE_TO_VIRUS_BY_VIRUS | MSigDB lists | GO_REGULATION_OF_DEFENSE_RESPONSE_TO_VIRUS_BY_VIRUS | 29 | 10 | 17377 | 2626 |
ELMO1,RAC1,AP1M1,AP1S1,AP2B1,PACS1,ARF1,AP1B1,AP2S1,HLA-A |
| 7.770e-03 | -4.86 | LANG_MYB_FAMILY_TARGETS | MSigDB lists | LANG_MYB_FAMILY_TARGETS | 29 | 10 | 17377 | 2626 |
SEC31A,CCT2,PPP3CA,COPA,CASP6,NSUN2,API5,SLC20A1,BIRC2,CBX4 |
| 7.770e-03 | -4.86 | MODULE_229 | MSigDB lists | MODULE_229 | 29 | 10 | 17377 | 2626 |
TFAP4,DHX9,DHX8,DDX5,CITED2,BLM,TRIM28,DDX23,PRPF4B,XRCC5 |
| 7.770e-03 | -4.86 | GO_MEMBRANE_INVAGINATION | MSigDB lists | GO_MEMBRANE_INVAGINATION | 29 | 10 | 17377 | 2626 |
CHMP2A,HGS,CHMP4A,ATG9A,ELMO1,RAC1,MYH9,BECN1,SMURF1,ABCA1 |
| 7.770e-03 | -4.86 | GO_ADP_BINDING | MSigDB lists | GO_ADP_BINDING | 29 | 10 | 17377 | 2626 |
ATP1A1,MYO18A,TAP1,MSH2,MYH9,GLUD1,RUVBL2,MYO9B,PPP5C,MSH6 |
| 7.790e-03 | -4.85 | GCM_SUFU | MSigDB lists | GCM_SUFU | 71 | 19 | 17377 | 2626 |
ZNF84,CRNKL1,UBQLN2,CDIPT,ZFAND5,FOXO3,REPS1,BSDC1,NEIL2,MTMR3,FBXO3,SCARB2,EIF4ENIF1,BRPF3,VPS26B,LUC7L3,PPIG,SS18L1,CHTOP |
| 7.790e-03 | -4.85 | GO_REGULATION_OF_VIRAL_GENOME_REPLICATION | MSigDB lists | GO_REGULATION_OF_VIRAL_GENOME_REPLICATION | 71 | 19 | 17377 | 2626 |
PPIB,STAU1,PPIE,YTHDC2,ILF3,EIF2AK4,ISG15,RAD23A,CCNK,DDX5,BCL2,MAVS,RNASEL,PARP10,PABPC1,ZC3HAV1,IFI16,DDB1,SRPK2 |
| 7.790e-03 | -4.85 | GO_REGULATION_OF_PLASMA_MEMBRANE_ORGANIZATION | MSigDB lists | GO_REGULATION_OF_PLASMA_MEMBRANE_ORGANIZATION | 71 | 19 | 17377 | 2626 |
PDPK1,TGFB1,RHOG,GOPC,ACSL3,NKD2,CIB1,EZR,BCL2L1,APPL1,SH3GLB1,KIF5B,PPP2R5A,CSK,DNM2,ITGB1,VPS4A,TMBIM1,NUMB |
| 7.795e-03 | -4.85 | REACTOME_P38MAPK_EVENTS | MSigDB lists | REACTOME_P38MAPK_EVENTS | 13 | 6 | 17377 | 2626 |
KRAS,NRAS,MAPK14,RALB,MAPKAPK3,HRAS |
| 7.795e-03 | -4.85 | GO_RNA_POLYMERASE_II_CORE_BINDING | MSigDB lists | GO_RNA_POLYMERASE_II_CORE_BINDING | 13 | 6 | 17377 | 2626 |
CTR9,PAF1,ELP4,RPRD1B,CDC73,ZNF326 |
| 7.795e-03 | -4.85 | GO_PRP19_COMPLEX | MSigDB lists | GO_PRP19_COMPLEX | 13 | 6 | 17377 | 2626 |
CTNNBL1,XAB2,POLR2A,CDC5L,PRPF19,CRNKL1 |
| 7.795e-03 | -4.85 | INAMURA_LUNG_CANCER_SCC_SUBTYPES_UP | MSigDB lists | INAMURA_LUNG_CANCER_SCC_SUBTYPES_UP | 13 | 6 | 17377 | 2626 |
DNAJC9,PA2G4,PATL1,SMNDC1,MEAF6,CS |
| 7.795e-03 | -4.85 | GO_H4_HISTONE_ACETYLTRANSFERASE_ACTIVITY | MSigDB lists | GO_H4_HISTONE_ACETYLTRANSFERASE_ACTIVITY | 13 | 6 | 17377 | 2626 |
USP22,WDR5,KAT2A,NAA60,NAA50,OGT |
| 7.795e-03 | -4.85 | WU_APOPTOSIS_BY_CDKN1A_NOT_VIA_TP53 | MSigDB lists | WU_APOPTOSIS_BY_CDKN1A_NOT_VIA_TP53 | 13 | 6 | 17377 | 2626 |
CDC6,SMPD4,SPAG5,CENPF,HSPA1B,MYBL2 |
| 7.795e-03 | -4.85 | GO_DNA_DIRECTED_RNA_POLYMERASE_I_COMPLEX | MSigDB lists | GO_DNA_DIRECTED_RNA_POLYMERASE_I_COMPLEX | 13 | 6 | 17377 | 2626 |
POLR1B,POLR2L,POLR2K,CD3EAP,ZNRD1,TWISTNB |
| 7.795e-03 | -4.85 | GO_SINGLE_STRANDED_DNA_DEPENDENT_ATPASE_ACTIVITY | MSigDB lists | GO_SINGLE_STRANDED_DNA_DEPENDENT_ATPASE_ACTIVITY | 13 | 6 | 17377 | 2626 |
RFC3,RAD18,RFC2,HELB,CHTF18,POLQ |
| 7.795e-03 | -4.85 | GO_MITOTIC_CHROMOSOME_CONDENSATION | MSigDB lists | GO_MITOTIC_CHROMOSOME_CONDENSATION | 13 | 6 | 17377 | 2626 |
NUSAP1,SMC2,NCAPG,AKAP8,CDCA5,SMC4 |
| 7.795e-03 | -4.85 | GO_RESPONSE_TO_MISFOLDED_PROTEIN | MSigDB lists | GO_RESPONSE_TO_MISFOLDED_PROTEIN | 13 | 6 | 17377 | 2626 |
ANKZF1,DERL1,SDF2L1,CLU,ATXN3,RNF5 |
| 7.795e-03 | -4.85 | GO_S_ADENOSYLHOMOCYSTEINE_METABOLIC_PROCESS | MSigDB lists | GO_S_ADENOSYLHOMOCYSTEINE_METABOLIC_PROCESS | 13 | 6 | 17377 | 2626 |
AHCY,DNMT3A,ICMT,AHCYL1,DNMT1,MRI1 |
| 7.795e-03 | -4.85 | REACTOME_POL_SWITCHING | MSigDB lists | REACTOME_POL_SWITCHING | 13 | 6 | 17377 | 2626 |
POLA2,RFC3,PCNA,PRIM2,RFC2,PRIM1 |
| 7.795e-03 | -4.85 | PARK_APL_PATHOGENESIS_UP | MSigDB lists | PARK_APL_PATHOGENESIS_UP | 13 | 6 | 17377 | 2626 |
UBE4A,HINT1,SOX4,SUCLG1,PSMB9,SELPLG |
| 7.795e-03 | -4.85 | CAFFAREL_RESPONSE_TO_THC_24HR_3_DN | MSigDB lists | CAFFAREL_RESPONSE_TO_THC_24HR_3_DN | 13 | 6 | 17377 | 2626 |
RRM2,NUSAP1,WBP1,CDC42,PSMD8,CSNK1G1 |
| 7.796e-03 | -4.85 | GO_NEGATIVE_REGULATION_OF_VIRAL_PROCESS | MSigDB lists | GO_NEGATIVE_REGULATION_OF_VIRAL_PROCESS | 86 | 22 | 17377 | 2626 |
TRIM8,TRIM11,ILF3,EIF2AK4,TRIM28,ISG15,CCNK,TFAP4,TRIM26,SP100,ZNF639,STAT1,PML,TARDBP,TRIM32,RNASEL,MAVS,PARP10,ZC3HAV1,IFI16,TRIM14,SRPK2 |
| 7.806e-03 | -4.85 | UBTF (upstream binding transcription factor) | protein interactions | 7343 | 90 | 24 | 17029 | 2761 |
EWSR1,MPHOSPH8,SHPRH,CSNK2A1,RTF1,KRAS,BRCA1,PIP4K2A,LMNA,MAPK3,UBTF,RB1,RRN3,MDM2,CCNA2,CD3EAP,AHSA1,TCOF1,CDK2,NKAPD1,SMURF1,MAPK1,CTDSP2,IFI16 |
| 7.822e-03 | -4.85 | SAP_dom_sf | interpro domains | IPR036361 | 25 | 9 | 18492 | 2768 |
SARNP,RAD18,SAFB,HNRNPUL2,PIAS2,RFFL,SAFB2,SLTM,CCAR1 |
| 7.823e-03 | -4.85 | Degradation of GLI2 by the proteasome | REACTOME pathways | R-HSA-5610783 | 61 | 18 | 10287 | 1696 |
PSMA8,RBX1,PSMB7,PSMA1,CUL1,CSNK1A1,PRKACA,PSMB9,PSMD9,PSMB3,PSMC4,PSMD2,PSMA6,PSMD1,RPS27A,PSMD3,PSMD8,PSMC1 |
| 7.823e-03 | -4.85 | GLI3 is processed to GLI3R by the proteasome | REACTOME pathways | R-HSA-5610785 | 61 | 18 | 10287 | 1696 |
PSMA8,RBX1,PSMB7,PSMA1,CUL1,CSNK1A1,PRKACA,PSMB9,PSMD9,PSMB3,PSMC4,PSMD2,PSMA6,PSMD1,RPS27A,PSMD3,PSMD8,PSMC1 |
| 7.823e-03 | -4.85 | Degradation of GLI1 by the proteasome | REACTOME pathways | R-HSA-5610780 | 61 | 18 | 10287 | 1696 |
PSMA8,RBX1,PSMB7,PSMA1,CUL1,PRKACA,PSMB9,PSMD9,PSMB3,PSMC4,PSMD2,PSMA6,PSMD1,RPS27A,PSMD3,PSMD8,PSMC1,NUMB |
| 7.841e-03 | -4.85 | PURBEY_TARGETS_OF_CTBP1_AND_SATB1_UP | MSigDB lists | PURBEY_TARGETS_OF_CTBP1_AND_SATB1_UP | 76 | 20 | 17377 | 2626 |
CPNE1,PNISR,TMEM184B,HLA-E,DCTN2,RPS10,LDHA,PSMA1,PKMYT1,PCBP1,RPSA,CHAF1A,PAIP2,DDX17,ZNF330,WDR59,ACTB,CHEK2,RAD51D,ARID4A |
| 7.843e-03 | -4.85 | GSE45365_HEALTHY_VS_MCMV_INFECTION_CD11B_DC_DN | MSigDB lists | GSE45365_HEALTHY_VS_MCMV_INFECTION_CD11B_DC_DN | 165 | 37 | 17377 | 2626 |
SEPHS2,SKA3,HJURP,DEPDC1,FOXM1,PTTG1,CENPF,TPX2,CDCA3,CDCA8,NUF2,CCNB1,MYL6B,SPAG5,CALM2,DTL,PRC1,FAM89B,MARCH2,GINS1,PLK1,TK1,ASPM,PBK,MKI67,RRM2,AURKB,ANLN,SHCBP1,TMEM201,KIF18B,BIRC5,CEP55,CDCA5,CBLN2,UBE2C,CCNB2 |
| 7.847e-03 | -4.85 | UAP1L1 (UDP-N-acetylglucosamine pyrophosphorylase 1 like 1) | protein interactions | 91373 | 6 | 4 | 17029 | 2761 |
SDHB,OAT,RAB11B,WDR1 |
| 7.847e-03 | -4.85 | Rmi1 (RecQ mediated genome instability 1) | protein interactions | 74386 | 6 | 4 | 17029 | 2761 |
RPA2,BLM,RMI2,TOP3A |
| 7.847e-03 | -4.85 | IFI6 (interferon alpha inducible protein 6) | protein interactions | 2537 | 6 | 4 | 17029 | 2761 |
ACTB,APP,POLR2A,CIB1 |
| 7.847e-03 | -4.85 | TLDC2 (TBC/LysM-associated domain containing 2) | protein interactions | 140711 | 6 | 4 | 17029 | 2761 |
ATP6V1D,ATP6V1C1,ATP6V1B2,KLHL15 |
| 7.847e-03 | -4.85 | MLLT11 (MLLT11, transcription factor 7 cofactor) | protein interactions | 10962 | 6 | 4 | 17029 | 2761 |
CYLD,PTPN18,AGO2,CUL3 |
| 7.847e-03 | -4.85 | Vim (vimentin) | protein interactions | 22352 | 6 | 4 | 17029 | 2761 |
PHB2,ZBTB11,CENPJ,RAB7A |
| 7.847e-03 | -4.85 | Bcl2l11 (BCL2-like 11 (apoptosis facilitator)) | protein interactions | 12125 | 6 | 4 | 17029 | 2761 |
MCL1,BCL2,BCL2L1,DYNLL1 |
| 7.847e-03 | -4.85 | TMSB4Y (thymosin beta 4, Y-linked) | protein interactions | 9087 | 6 | 4 | 17029 | 2761 |
TERF2IP,EWSR1,POT1,TERF1 |
| 7.847e-03 | -4.85 | GLRX2 (glutaredoxin 2) | protein interactions | 51022 | 6 | 4 | 17029 | 2761 |
CYCS,PITPNB,MDH2,GPX4 |
| 7.847e-03 | -4.85 | RNU5A-1 (RNA, U5A small nuclear 1) | protein interactions | 26831 | 6 | 4 | 17029 | 2761 |
SND1,ZMYND11,EFTUD2,ILF3 |
| 7.847e-03 | -4.85 | METTL2B (methyltransferase like 2B) | protein interactions | 55798 | 6 | 4 | 17029 | 2761 |
APP,CENPU,MAPK3,METTL2A |
| 7.847e-03 | -4.85 | EPHX2 (epoxide hydrolase 2) | protein interactions | 2053 | 6 | 4 | 17029 | 2761 |
PEX5,MVP,EPHX2,TERF1 |
| 7.847e-03 | -4.85 | CAPRIN2 (caprin family member 2) | protein interactions | 65981 | 6 | 4 | 17029 | 2761 |
LRP5,PEX5,COPS6,FAM8A1 |
| 7.847e-03 | -4.85 | HTNVsSgp1 (nucleocapsid protein) | protein interactions | 2943078 | 6 | 4 | 17029 | 2761 |
UBE2I,CHD3,HIPK2,PIAS2 |
| 7.847e-03 | -4.85 | STK32C (serine/threonine kinase 32C) | protein interactions | 282974 | 6 | 4 | 17029 | 2761 |
MCM5,RMC1,FDFT1,CDC37 |
| 7.847e-03 | -4.85 | ARHGAP31 (Rho GTPase activating protein 31) | protein interactions | 57514 | 6 | 4 | 17029 | 2761 |
CYLD,CDC42,SMURF1,RAC1 |
| 7.847e-03 | -4.85 | Rab3gap1 (RAB3 GTPase activating protein subunit 1) | protein interactions | 226407 | 6 | 4 | 17029 | 2761 |
RABGAP1L,SRRT,PDF,YJU2 |
| 7.847e-03 | -4.85 | DBNDD2 (dysbindin domain containing 2) | protein interactions | 55861 | 6 | 4 | 17029 | 2761 |
CSNK1G2,CSNK1G3,CSNK1D,LMNA |
| 7.876e-03 | -4.84 | REACTOME_SIGNALING_BY_PDGF | MSigDB lists | REACTOME_SIGNALING_BY_PDGF | 117 | 28 | 17377 | 2626 |
PDPK1,NRAS,TSC2,NCK1,AKT2,RAF1,PRKAR1B,KRAS,AKT1S1,PRKACA,FOXO3,MAP2K2,MAPK3,CRKL,CALM2,MDM2,PTEN,STAT6,PIK3R2,ADCY9,STAT1,CDKN1B,CREB1,STAT3,MAPK1,HRAS,ADCY7,MLST8 |
| 7.876e-03 | -4.84 | GO_PROTEIN_ACETYLATION | MSigDB lists | GO_PROTEIN_ACETYLATION | 117 | 28 | 17377 | 2626 |
NAT9,KAT2A,KAT7,MDH2,MECP2,LDB1,ELP4,TAF6L,USP22,WDR5,SUPT7L,MBD3,MEAF6,SAP130,IRF4,MBIP,BRPF3,OGT,NAA50,TAF5L,BEND3,TAF12,RUVBL2,NCOA1,NAA20,ATF2,NAA60,NCOA2 |
| 7.883e-03 | -4.84 | phagophore assembly site | cellular component | GO:0000407 | 34 | 11 | 18223 | 2701 |
ULK3,ATG9A,VMP1,RB1CC1,RAB7A,ATG2B,ATG13,WIPI2,WDR45B,BECN1,PLEKHF2 |
| 7.883e-03 | -4.84 | nuclear heterochromatin | cellular component | GO:0005720 | 34 | 11 | 18223 | 2701 |
DNMT3A,H2AFZ,KMT5C,MPHOSPH8,SUZ12,UHRF2,H2AFY,BEND3,SIRT2,TRIM28,CBX3 |
| 7.890e-03 | -4.84 | Regulation of TP53 Degradation | REACTOME pathways | R-HSA-6804757 | 35 | 12 | 10287 | 1696 |
PDPK1,PPP2CA,USP7,MDM2,CCNA2,RPS27A,AKT2,RFFL,CHEK2,CDK2,CDKN2A,MLST8 |
| 7.891e-03 | -4.84 | central_nervous_system-brain-glioma-gliosarcoma | COSMIC cancer mutations | central_nervous_system-brain-glioma-gliosarcoma | 17 | 7 | 17385 | 2587 |
CDKN2C,KRAS,NRAS,H3F3A,PTEN,SF3B1,HRAS |
| 7.891e-03 | -4.84 | small_intestine-jejunum-carcinoma-adenocarcinoma | COSMIC cancer mutations | small_intestine-jejunum-carcinoma-adenocarcinoma | 17 | 7 | 17385 | 2587 |
GNAS,KRAS,STK11,NRAS,SMAD4,CDKN2A,PTPN11 |
| 7.891e-03 | -4.84 | jejunum | COSMIC cancer mutations | jejunum | 17 | 7 | 17385 | 2587 |
GNAS,KRAS,STK11,NRAS,SMAD4,CDKN2A,PTPN11 |
| 7.891e-03 | -4.84 | leiomyoma | COSMIC cancer mutations | leiomyoma | 17 | 7 | 17385 | 2587 |
GNAS,KRAS,BRCA1,JAK1,SF3B1,JAZF1,PTPN11 |
| 7.891e-03 | -4.84 | adult_T_cell_lymphoma-leukaemia | COSMIC cancer mutations | adult_T_cell_lymphoma-leukaemia | 17 | 7 | 17385 | 2587 |
RB1,KRAS,NRAS,JAK1,STAT3,SF3B1,CDKN2A |
| 7.891e-03 | -4.84 | soft_tissue-smooth_muscle-leiomyoma | COSMIC cancer mutations | soft_tissue-smooth_muscle-leiomyoma | 17 | 7 | 17385 | 2587 |
GNAS,KRAS,BRCA1,JAK1,SF3B1,JAZF1,PTPN11 |
| 7.891e-03 | -4.84 | haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-adult_T_cell_lymphoma-leukaemia | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-adult_T_cell_lymphoma-leukaemia | 17 | 7 | 17385 | 2587 |
KRAS,RB1,NRAS,JAK1,STAT3,SF3B1,CDKN2A |
| 7.892e-03 | -4.84 | basal_cell_carcinosarcoma | COSMIC cancer mutations | basal_cell_carcinosarcoma | 21 | 8 | 17385 | 2587 |
GNAS,NRAS,TSC2,SMARCA4,KRAS,NOTCH2,KMT2C,CDKN2A |
| 7.892e-03 | -4.84 | skin-forearm-carcinoma-basal_cell_carcinosarcoma | COSMIC cancer mutations | skin-forearm-carcinoma-basal_cell_carcinosarcoma | 21 | 8 | 17385 | 2587 |
GNAS,NRAS,TSC2,SMARCA4,KRAS,NOTCH2,KMT2C,CDKN2A |
| 7.892e-03 | -4.84 | signet_ring_adenocarcinoma | COSMIC cancer mutations | signet_ring_adenocarcinoma | 21 | 8 | 17385 | 2587 |
EZR,FGFR3,KRAS,STK11,PTEN,CDKN2A,MSH6,MSH2 |
| 7.892e-03 | -4.84 | central_nervous_system-parietal_lobe-glioma-astrocytoma_Grade_IV | COSMIC cancer mutations | central_nervous_system-parietal_lobe-glioma-astrocytoma_Grade_IV | 21 | 8 | 17385 | 2587 |
KRAS,H3F3A,NF1,PTEN,SF3B1,CDKN2A,MSH6,MSH2 |
| 7.892e-03 | -4.84 | stomach-carcinoma-signet_ring_adenocarcinoma | COSMIC cancer mutations | stomach-carcinoma-signet_ring_adenocarcinoma | 21 | 8 | 17385 | 2587 |
EZR,FGFR3,KRAS,STK11,PTEN,CDKN2A,MSH6,MSH2 |
| 7.899e-03 | -4.84 | Serotonin Receptor 2 and ELK-SRF/GATA4 signaling | WikiPathways | WP732 | 20 | 8 | 5312 | 837 |
NRAS,RAF1,KRAS,ELK1,MAPK1,MAP2K2,HRAS,MAPK3 |
| 7.916e-03 | -4.84 | CCNL1 (cyclin L1) | protein interactions | 57018 | 9 | 5 | 17029 | 2761 |
JMJD6,CDK11A,APP,ISG15,RNPS1 |
| 7.916e-03 | -4.84 | RAD54L (RAD54 like) | protein interactions | 8438 | 9 | 5 | 17029 | 2761 |
NCK1,WDYHV1,LIMK1,E2F4,E2F1 |
| 7.916e-03 | -4.84 | EIF1AY (eukaryotic translation initiation factor 1A, Y-linked) | protein interactions | 9086 | 9 | 5 | 17029 | 2761 |
ATXN1,EIF5,HUWE1,CUL3,SRPK2 |
| 7.916e-03 | -4.84 | PLEKHG2 (pleckstrin homology and RhoGEF domain containing G2) | protein interactions | 64857 | 9 | 5 | 17029 | 2761 |
CCNA2,RHOA,CDC42,APP,RAC1 |
| 7.916e-03 | -4.84 | BICRA (BRD4 interacting chromatin remodeling complex associated protein) | protein interactions | 29998 | 9 | 5 | 17029 | 2761 |
BRD4,EWSR1,NEIL3,SMARCD1,BCL7C |
| 7.916e-03 | -4.84 | ARHGAP15 (Rho GTPase activating protein 15) | protein interactions | 55843 | 9 | 5 | 17029 | 2761 |
DHPS,SMURF1,APP,RAC1,PRNP |
| 7.916e-03 | -4.84 | FAM3B (family with sequence similarity 3 member B) | protein interactions | 54097 | 9 | 5 | 17029 | 2761 |
CBWD1,LRP5,TM9SF4,APP,ANKRD46 |
| 7.916e-03 | -4.84 | STK19 (serine/threonine kinase 19) | protein interactions | 8859 | 9 | 5 | 17029 | 2761 |
SP3,IMPDH1,SLC29A1,POLE,POLR2G |
| 7.916e-03 | -4.84 | GPD1 (glycerol-3-phosphate dehydrogenase 1) | protein interactions | 2819 | 9 | 5 | 17029 | 2761 |
MDH1,IDH3B,GNPNAT1,GPD1L,NMD3 |
| 7.916e-03 | -4.84 | Ctcf (CCCTC-binding factor) | protein interactions | 13018 | 9 | 5 | 17029 | 2761 |
CTCF,EBNA1BP2,LLPH,FAU,NOP2 |
| 7.916e-03 | -4.84 | ACE (angiotensin I converting enzyme) | protein interactions | 1636 | 9 | 5 | 17029 | 2761 |
MYH9,CSNK2A1,ACTB,EWSR1,LMNA |
| 7.916e-03 | -4.84 | APOBEC3G (apolipoprotein B mRNA editing enzyme catalytic subunit 3G) | protein interactions | 60489 | 9 | 5 | 17029 | 2761 |
HSPA4,MAP3K5,PRKACA,CBFB,APP |
| 7.916e-03 | -4.84 | PABPC4L (poly(A) binding protein cytoplasmic 4 like) | protein interactions | 132430 | 9 | 5 | 17029 | 2761 |
CSDE1,DGCR8,ZC3HAV1,GSPT2,H2AFX |
| 7.916e-03 | -4.84 | DCAF17 (DDB1 and CUL4 associated factor 17) | protein interactions | 80067 | 9 | 5 | 17029 | 2761 |
COPS6,ZMAT3,DDA1,PTTG1,DDB1 |
| 7.916e-03 | -4.84 | PAPOLG (poly(A) polymerase gamma) | protein interactions | 64895 | 9 | 5 | 17029 | 2761 |
LZTR1,HNRNPR,HARS,DHX29,DCTN1 |
| 7.916e-03 | -4.84 | ZNF350 (zinc finger protein 350) | protein interactions | 59348 | 9 | 5 | 17029 | 2761 |
BRCA1,NEK1,VHL,TRIM28,USP21 |
| 7.916e-03 | -4.84 | NME6 (NME/NM23 nucleoside diphosphate kinase 6) | protein interactions | 10201 | 9 | 5 | 17029 | 2761 |
APP,SSSCA1,DBF4,RCC1L,MRPL12 |
| 7.916e-03 | -4.84 | TIGAR (TP53 induced glycolysis regulatory phosphatase) | protein interactions | 57103 | 9 | 5 | 17029 | 2761 |
TSC2,PCBP1,APP,RPL11,TKT |
| 7.916e-03 | -4.84 | EIF2S3B (eukaryotic translation initiation factor 2 subunit gamma B) | protein interactions | 255308 | 9 | 5 | 17029 | 2761 |
RPS24,NOP2,CDC123,SRSF1,ZNF326 |
| 7.917e-03 | -4.84 | Ubiquitin_dom | interpro domains | IPR000626 | 57 | 16 | 18492 | 2768 |
UBL3,UBQLN4,TMUB1,SUMO2,NFATC2IP,HERPUD2,USP48,UBQLN2,ISG15,UBLCP1,RAD23A,SNRNP25,RPS27A,RAD23B,UHRF2,FAU |
| 7.931e-03 | -4.84 | peptide N-acetyltransferase activity | molecular function | GO:0034212 | 70 | 19 | 17224 | 2647 |
KAT2A,KAT7,ELP4,EDF1,TAF6L,USP22,WDR5,SUPT7L,TEX30,OGT,NAA50,TAF5L,KANSL2,TAF12,NCOA1,NAA20,ATF2,NAA60,NAA35 |
| 7.931e-03 | -4.84 | breast-carcinoma | COSMIC cancer mutations | breast-carcinoma | 15509 | 2343 | 17385 | 2587 |
HECA,ZBTB10,ABCC10,HEXB,TGOLN2,CCNL2,FBXO22,EEF2K,THAP4,RAD23B,ATP13A3,DNM2,FTSJ3,USP34,CCDC57,ERCC1,NRAS,EHMT1,KIF15,HNRNPF,WDHD1,MIER2,DIDO1,RAB22A,SMAD2,RPS27A,MYO18A,OGT,MPV17,COX5A,SMAD1,ZNF75A,ANXA11,SLC25A33,ZNF720,GGA1,MUM1,CCZ1,TRIO,CUTA,RAB23,KCTD17,HAUS4,EIF2AK4,APH1B,PARN,CDC73,MYL6B,ATG4A,TMEM179B,ERV3-1,SMC3,C4orf3,GEMIN4,MVP,NUP85,PPP6R1,PABPC1,NSUN4,PPA1,IFRD1,AGGF1,FOXK1,RBM42,GTPBP4,MAP7D1,MRPL16,ELK1,EIF4H,RDH11,MAGED2,KPNA1,ETS2,TYW5,WIPI2,RUFY3,PDLIM5,ACSF2,FAM72D,EXOC3,STARD7,VTI1A,SLC35B2,INO80E,RCOR3,LCLAT1,CPNE3,KIAA1147,RBM23,ZNF420,AHCTF1,TBC1D22A,TBC1D14,GMEB1,NSFL1C,SEPT11,GPD1L,ZC3H3,ARL5A,PDCL3,SNX8,ERMP1,IDH3A,POLR2D,HTATIP2,MEF2D,TMEM147,GSTCD,TANC1,MAT2A,VPS26B,NSMCE2,CORO1C,CAMKMT,PPP5C,PITRM1,TUBB,COMMD10,ZNF445,HABP4,CCM2,FLOT1,BTN3A1,ATG2B,PPP1R3B,GOLM1,ZBTB45,HUWE1,ZNF260,NAA50,ANXA5,LTN1,UBE3B,NAP1L4,ZNF710,ST8SIA2,RPL22L1,MED22,SPTAN1,STAU1,TCTEX1D2,DDX24,TACC1,MRS2,LDHA,HEBP2,LLPH,RAB3IP,PICALM,SH3BP5,SLC19A1,ACOX1,FAM3C,AEN,PARP10,YWHAH,THAP5,GPATCH4,FAM129A,TRIM11,YTHDC2,SNX15,RBM8A,ENSA,SND1,RUFY1,TRIM65,ZER1,PRNP,KRR1,RAB8A,NUP210,NT5DC1,NOC2L,EIF5,TACC3,VPS13B,RYBP,PTPN18,MIOS,SNRPB,MBLAC2,CDC6,UTP3,PBRM1,ODC1,USP21,TRAM2,FBXO28,BCL7C,ARRDC1,ADAM9,DVL1,NUMB,ZNF564,C1orf74,CTU2,PARP12,ZCCHC9,CENPF,CHCHD2,NCKAP1,RSAD1,TNS3,SUB1,RINL,SSBP3,KIF13B,XPA,AHCY,RBM3,GLE1,MRPL48,LRSAM1,HDHD2,NTPCR,NSDHL,AMD1,CAMSAP1,ZNF761,ICAM2,STYXL1,APPL1,BBS12,ANKRD46,SDHB,PCM1,GALNT2,TMEM168,NLRC5,MYO9A,BTBD10,CCNB2,USP7,GLT8D1,RPLP2,SUCLG1,ARID2,TMX4,SLC2A1,ATP6V1B2,PCBP1,LYN,BCAP31,VAV1,TMEM69,MRPL50,PSMA6,ZNF473,ZNF302,BRPF3,TARDBP,BCAP29,CTDSP2,PRPF19,PPIF,KDM3B,MND1,CLCN3,BIRC3,ANKRD33B,PPIE,VDAC1,EIF3H,TMEM201,GLOD4,IDE,DHX16,UHRF2,CHMP4B,PARD3,BCL2L12,C19orf53,KLHL21,PDAP1,TMX3,CDCA8,GTF3A,ARF1,SLC12A9,TUBGCP2,DNAJB9,HOMER1,POLR1B,RBM15B,PPAN,RHOA,RPRD1A,BTAF1,TOP3A,ARHGEF12,PCGF1,DDX23,RAB18,CACNB1,TRIM26,PDCD6,ATP6V1D,L3MBTL3,FAM110A,NEIL3,CTBS,BBX,IMPDH1,TAF12,NR2F2,PGAM1,HIPK3,IFI16,TXN,NUP188,H2AFZ,PNISR,TMEM203,PRKCSH,USP39,UBE2I,ASPHD2,RAB4A,TRA2B,SUCLG2,TAF5L,ZNF800,CDC5L,ZNF524,SGCE,OSBP2,NSUN2,USP22,CLNS1A,EIF3A,ZMYM3,DOT1L,IWS1,ANKRD10,WAS,KIF18B,TPP2,C1orf109,ZMAT3,PRPF38B,RECQL,C9orf78,EWSR1,GADD45G,RRM1,ACAP1,B4GALT1,FAM136A,SUPT7L,TMEM165,CNOT3,NPLOC4,WDR48,SPAG5,RTKN,CEP104,EXOSC7,KLHL5,LRRC8D,MSH2,PIGG,OSTF1,FBXL7,MRPL40,TNRC18,SYTL3,FAM171A1,APOL1,GCC2,PRIM2,ELL2,RDH10,GORASP2,CAPZA2,ADRB2,CCT8,MTR,PHF6,SLCO4A1,TTC13,GOLGA2,RBMX,MED15,PIAS2,APPL2,SAMD8,CDKN2A,NUDT3,ZNF511,ATXN3,RAF1,KIAA0232,C2orf49,EPM2A,CCNA2,MTMR4,BRI3,TP53BP2,AQR,RBM12B,ILKAP,CDK12,SAP30,BRD4,DRAP1,NARF,LRRC8A,ELP4,ABHD11,PKMYT1,ASB13,TRIM28,SUPT16H,EIF3K,CHMP4A,CBWD1,ATF6,XRCC4,PRPF4B,ADAM23,NDUFS1,DEPDC1,MECP2,SECISBP2,HMG20A,WWP2,JAKMIP1,SLC25A36,CCNK,DNAJC8,ELP5,AXIN2,CITED2,JMJD4,ANKRD37,KAT2A,TMEM126B,RABIF,ADSL,PACS1,BMS1,KCNQ1,OTUD3,ARSK,MACF1,KIF11,KLF6,COMMD4,SMAP2,SH3GLB1,MYO1F,CBX3,TMEM127,INF2,DUSP11,DDX5,WDR62,TAF6,ESPL1,DDB1,DEF6,FAM83G,IPO4,UBL3,PIGM,NAT9,LYRM4,GPR132,UBE2Q1,BRIX1,SF3B2,PCYOX1L,CDC42,SYNM,GOT2,JAZF1,HADHB,SLC35C2,CNNM3,CARM1,SRPK2,WDR41,LARS,ZCCHC10,CCDC138,LRBA,TMEM216,SUMF2,KMT2C,OGFR,PRPSAP1,ASF1B,RPL37,MAN2A2,EIF4ENIF1,NIP7,U2SURP,MIA2,ZNF268,VPS4A,ATP6V0E1,PPP1R2,PM20D2,XPNPEP3,LYAR,POLR2I,TRAFD1,SUGP2,GBA,EIF2A,SYVN1,DAPK3,ARHGAP15,MASTL,UAP1,NFIL3,FN3KRP,YWHAZ,CTSA,TOB1,TSEN15,ADNP2,TCF12,PRKAB1,MDH2,SMARCA4,ORC1,RRN3,UBXN2A,IARS,CD3EAP,KIF14,CS,CSTF1,POU2AF1,UBQLN4,NXT1,HPDL,PGGT1B,SELPLG,SMU1,ATXN1,OGDH,BICD2,CADM1,EDEM2,HERPUD2,TOLLIP,FANCE,MBD3,PDHX,RPS9,SURF4,DUS3L,ARNTL,ANP32E,FKBP5,TMEM101,CCDC125,ABCA1,PDCD2L,GCLM,RAE1,DCTN2,NUP54,CHIC2,PAWR,MXD4,DCUN1D4,PIP4K2A,XPR1,FERMT3,KIF5B,KLHL20,SEC24C,RRBP1,ARHGEF2,ANP32A,LDLRAD3,C12orf75,STAT3,MYO5A,NIPAL3,TXNL1,PHF20L1,DCAF6,FAM49B,TMEM39A,ATP2C1,RFFL,COG1,RCOR1,PRMT2,TFEB,LEMD2,SERF1B,UPF1,ELMO1,ZC3H7B,DTX4,ZMIZ1,HRAS,CCDC93,TMED7,PIGQ,AGPAT1,CNTROB,PPP1R16B,MIS12,GSDMB,TTC9C,PDS5B,NUP153,PGAP2,TMEM115,PLEKHM3,DCUN1D5,PLEKHF2,BRMS1,TRIM47,WDR11,AXIN1,SMG9,TRIM52,LONP2,NDUFV2,PHF23,CERK,SLC4A2,EZH1,ITGB5,LMNA,MCTS1,DDX56,EIF2S2,SLC38A5,FOXN2,CARS2,PRRC2A,C16orf72,RB1CC1,ZMYND11,PGS1,MYBL2,UHRF1BP1,MPG,MATR3,CYB5A,NCDN,POLR2J,SETD3,TEX30,CNOT6,NDE1,EGLN1,ZNF207,ANKRD27,PPP1R37,ABCA3,IVNS1ABP,MON1B,RMI2,TMEM97,NIT2,NUF2,ZNF267,TCF19,TMEM161B,KTN1,APP,PRKD3,CLUAP1,ATP2A2,UTP18,GRSF1,DUT,ZCCHC2,ANAPC7,RNF19A,FAM76B,CLN6,TMEM9,GCC1,RNF169,ADCY7,ENPP4,RNPS1,CDCA2,FKBP3,GPR137,DDX17,CHCHD3,PEX5,CDC16,HIPK2,MBOAT1,TICAM1,ZBTB11,ANXA6,TMBIM4,GMCL1,UBE4A,ETS1,WRB,ZNF92,PNO1,CAPN2,ADD3,SUV39H2,TTLL12,TPCN1,TMX1,HNRNPM,MFSD12,LDHB,PPP3CA,NUDT8,POLK,JTB,MTMR12,ZP3,PDE3B,KIF18A,CCDC6,MAPK6,LY75,SLC25A19,RGL1,PSAP,WDR76,IGBP1,FAF1,SNAPIN,COX15,AGRN,THOC1,GPBP1L1,PPP1R15B,CSNK2A1,EBNA1BP2,GIT2,BIRC2,ATPAF1,DLG5,ABL2,XRCC2,ZFYVE27,MCMBP,PTPRK,CDC37,METTL1,HARS,GMFB,ESYT1,ANLN,RHEB,DPYSL3,TBC1D17,TIMM13,CDCA4,TONSL,NAGLU,ACTB,ZNF45,CTCF,ASAH1,DOCK11,CRLF3,ASXL2,LRRC14,NUS1,SLC27A4,MDFIC,MAML1,CYTH1,NQO2,UTP15,EIF2AK1,EIF4G2,ZDHHC3,MOSPD3,ITPRIPL1,CDC27,SNAP23,PRMT7,KCTD7,NDUFA5,CYLD,UGP2,DYNLL1,COPE,HCFC1R1,ZADH2,GGPS1,RPAIN,RAD23A,ATP6V0B,PDK2,STRBP,DUS4L,PDCD2,SAP30L,SLC39A9,CLPTM1,RPL29,RPL35,DNAJC9,MTMR6,NFATC2,KDM1B,ARL5B,USP36,CCDC127,MRPL2,ATP1A1,CLK3,PSMD3,CEP55,DNAJC17,ZNF436,NCOA1,SLC25A39,ZC3HC1,ZNF146,ATXN7L2,CDC40,GOLIM4,SMAP1,RRP15,DAP,GNE,SMC6,ARFIP2,NKRF,BZW2,WRNIP1,PTGES3,CAMK2G,MLEC,ZNF202,PPWD1,RHOT2,NEU1,TPD52L2,GOLGA7,TWSG1,PGRMC1,GLG1,FAM126A,RPS6KC1,UBE2C,PPCS,NDUFB6,TMEM41B,ZDHHC8,PLXNA1,CCNB1,SLC20A1,COMMD6,ABHD14A,POLR3K,C14orf119,ASAP2,SNUPN,CNPY4,PLCL2,SEH1L,ATG9A,PBK,MKI67,DDX20,AMDHD2,SLC17A5,GALNT7,CCNF,FOXRED1,RBM47,PTER,WDR4,DHTKD1,TRAF5,HDAC2,PWWP2A,HSPH1,LIME1,MAPRE1,CHTF18,KIF23,SLC35B1,NOTCH2,PMF1,JMY,SLC31A1,SNX18,CTPS1,ATP6V0A2,PIKFYVE,RNF135,LPCAT1,EEF1D,TMED2,FTL,SIGMAR1,PIP4K2C,FAM133B,RIT1,PLEC,KDM3A,SF3A2,FAS,EPRS,ZNF777,TMEM54,QARS,TCOF1,CABLES1,NRBP1,DNMT3A,RWDD1,CKLF,TRIP10,SF3B1,CAST,SUZ12,RPS6KA1,RAC1,GPR89A,OLA1,SNN,GNB2,FLAD1,APLP2,KDM2A,TNPO2,CDKN1B,TALDO1,GPX4,ATP13A1,MAPRE2,ERF,CUL3,SLBP,KIAA1586,H2AFV,GAR1,POLG2,DHX57,NSA2,HSPA4,MRPL55,JAK1,GOLGA8A,TBL3,SEL1L,H2AFX,KLHDC4,B4GALT3,PDCD11,ATMIN,POLQ,POU3F2,OTUD5,NCOR2,ANKRD13D,PKP4,SCAMP3,BABAM1,CDCA3,SLC25A12,BLM,TMCC3,GTF2F1,RPL17,CRAT,AHSA1,PRC1,UPF2,COPS7B,SLC38A10,CNPY3,IFT46,TMEM160,TSHZ1,ZFP64,DENND4C,DENND1B,RPL8,ILF3,LRRC1,RHOT1,TSR2,MARK2,ECH1,PRDX1,PLD3,NUCB1,FBXO21,GNA12,C1orf131,PRDX3,HNRNPH3,TFDP1,STX18,KHSRP,ASNA1,CPEB2,BYSL,S100PBP,MIB2,IER2,PTMS,NOP2,UBN1,DCAF15,NF1,ALKBH5,MOGS,UBE2Z,TAF6L,MAPK14,BECN1,SNAPC4,RNF103,BCAT2,MBD4,METTL14,IMPAD1,ZNHIT6,RCSD1,PHTF1,SRI,KIF22,ZBTB22,NFU1,OGG1,TRIM14,ELOF1,COPS8,FYTTD1,TRIM8,RRM2,ABHD5,CXXC4,UBTF,PAF1,UEVLD,SPATA2,PQBP1,IARS2,ATXN2L,GALNT10,STARD3NL,RPS15,PIGN,AGTRAP,XPO7,SRRT,ZNF449,CAPZA1,GLTP,BCL2,KIFAP3,N4BP2,HP1BP3,VOPP1,THNSL1,CAND1,GNAS,TSC1,RBM25,CDCA5,ZFP90,NANP,RBBP4,ZBTB24,SMARCD1,MBD1,WASF2,MMACHC,TOMM20,IFI27L1,GNPNAT1,MPHOSPH8,HNRNPUL2,CHD1,MEAF6,C2orf68,CCDC50,AKAP8,RPN2,CHTOP,F2R,FAM3A,SCYL3,TMEM14C,ABI1,HTRA2,RLIM,FAM172A,ZNF500,PSMB7,NLN,WIPF1,BOLA1,BUD13,NDUFB1,PEF1,EIF3G,BTBD1,TAB2,CHCHD1,TULP3,WDR59,CANT1,SCARB1,GAS2,USP11,SMURF1,TSPAN5,CDS2,MAGEH1,MRPL42,EYA1,CDK2AP2,MRPS26,LETMD1,RGS1,HDDC2,MAN1A1,FBXO5,GART,TANK,PELO,BRD7,MRPL11,SAMD4B,ZDHHC18,GTF3C6,POLR3GL,WDR81,MEN1,ZNF407,MFN2,COX8A,ZRANB2,MBD6,IDH3B,TATDN1,ATP6V1C1,TSC2,LACTB2,CMTM6,RBM4,ZNF275,RPL23A,CDKN2C,NAPG,USF1,DNAAF2,MECR,AP1M1,UPRT,CRY2,ECD,MOB1A,RNF26,TIPARP,RHBDD2,MGAT5,BAK1,ZNF559,RHOBTB3,GABPA,WBP1,NUTF2,GINS4,KRIT1,AHNAK,RAD18,PDRG1,RNASEL,CHPF2,PDCD4,SMNDC1,NXT2,HIVEP3,KIAA0100,CLSPN,RHOC,DHX9,PDCD7,PSMD9,HAUS2,COPB2,CD59,TFAP4,RNFT1,MEGF8,RIMS3,EFTUD2,FBXO7,CPSF4,MRPL21,LUC7L2,EIF3L,MTA2,TYW1,USP10,ITM2A,SSR2,MTX1,SFXN5,FNTA,PDLIM1,TXNDC16,ZNF830,TMEM159,MRPL3,ALS2,FAM72A,TRIM41,KARS,NQO1,POC1A,ANK3,PTTG1,TPX2,TBC1D13,DAZAP2,GLRX3,STMN1,REPS1,CBWD5,ABHD16A,FBXL6,SH3BP1,UBA5,CLCN6,INTS12,RPRD1B,SZRD1,CPNE1,SEC61B,FAM118B,GOPC,E2F3,CIRBP,RPL38,CRNKL1,PFKFB3,GORAB,RAB1A,GIGYF1,TMEM184C,PPP2CA,KIF2A,CCDC14,LSM6,RNF38,SNRPG,CENPBD1,DMWD,USP13,ZFP91,TRMT6,IP6K2,WDR5,SLC25A43,IFT27,PMVK,RRP36,SRXN1,RPA2,PSMD2,CLIC4,PDCD10,CBWD2,COQ4,ITGB8,ARHGEF1,FBXL19,TTPAL,UTP20,MAGT1,GPS2,DBI,SSNA1,MRFAP1L1,TMEM131,WDR13,FANCI,PAPOLA,CREM,TET3,FANCL,GLIS2,IL6ST,INTS1,SLC44A1,MTPN,ASB6,PLK1,RPP25,CELSR2,SEPT9,APH1A,RAD51AP1,ZBED5,CKAP2L,PSMG1,UBE2V1,EAF2,IL12RB1,KRTCAP2,LSG1,NECAP2,C1orf122,ALG3,TRIM4,AGPAT2,CHD3,ZNF367,E2F4,PRPF4,KPNA2,BEND6,CLN3,DNAJC30,FAM208A,NGLY1,POT1,MYL12B,CCDC137,RMND5A,HJURP,PHB2,DNAJB2,FAM53C,NKD2,SDC2,KLC1,CDK13,ADCK5,DNAJB1,RAB6A,ARID1B,C1GALT1,MLX,UBE2Q2,CCP110,ZNF746,ARL6IP1,CTR9,NIPSNAP1,ABHD2,DCAF8,ACSL3,LDB1,MAP4K3,ARMC8,NMT2,IRF5,RPL36,HAUS8,MBIP,ORMDL2,COX7A2L,SIL1,FAM122A,DTD1,UNC13C,BCCIP,SART1,TRAF7,NDUFAF2,TOR1AIP1,ZNF416,LAGE3,TM9SF3,RRAGC,ZNF121,OIP5,NRF1,WDR44,PPME1,EFCAB11,RPAP1,CABLES2,LMAN1,AHCYL1,TOP1MT,STRAP,SPSB3,ZNF583,SNX25,ARHGAP17,POLR2G,KIAA0040,ZNF780B,PPT1,NUP155,DCLRE1C,MRPS14,RHBDF2,SUGP1,RBL1,FASTK,UBXN2B,STK38,AP1S1,SPRYD4,SLC22A23,H3F3A,CHID1,SMAD4,RAD51D,SLC30A9,CMAS,UNK,NADSYN1,HMGN3,NCAPG,SCYL2,FZD6,HERC3,GTPBP3,CTSS,ORC3,RNLS,YTHDC1,ACP2,HMGN5,CSRP1,METTL5,ABCF2,TUFM,RANGAP1,PNPLA8,HAGH,API5,ZFR,SEC23IP,E2F1,TMEM219,USP20,PDCD6IP,MAX,GXYLT1,LUZP1,ADAM10,CXXC1,TSC22D3,AP3M2,CUL1,GYG1,NANS,OAT,MYEF2,ANKRD26,PA2G4,NOL11,FIZ1,ZNF200,MARCH2,SLC26A2,SRSF10,SRP72,KLF10,LACTB,RFC2,CBFB,RAB2B,PRIM1,MAP3K4,HHEX,RPS14,MAP4,MRPL27,BTF3,PTPDC1,NMD3,PTOV1,COX5B,DNAJC5,SCOC,DHPS,ANKH,PRKAA1,C16orf87,VAV2,GSPT2,TATDN3,DLGAP4,PXMP2,PRPF39,PSEN1,ZNF79,PDXDC1,VPS25,NDUFS7,YY1AP1,C12orf10,FAM192A,RPN1,LHX8,ARPC5,ZNRF2,TPST1,DAPK1,PIK3IP1,CYC1,SOCS5,FDFT1,PIGT,EMB,WDR1,ZNF574,EXOSC9,ARID1A,FXR1,GOSR1,MAP2K2,TWISTNB,AKAP1,XRCC5,HMGN2,PI4K2A,CAT,DERL1,HSPBP1,ARAP1,USP32,FAM83D,CABIN1,SMPD4,GPI,CYTIP,REPS2,RAB11B,UROD,SLC39A13,POMP,BCL2L1,DECR1,RALB,SIAH1,ADCY9,LPIN2,MRPS27,SOCS6,TTC3,RNASEH2A,CFL1,ANKLE2,CDC123,OAF,VDAC2,EML4,ERC1,AMZ2,ANKZF1,RAD51C,ZNF282,DSN1,DDOST,DGCR8,SAFB,HAGHL,FTSJ1,RWDD4,LMBR1,NCLN,BEND3,EYA2,DYNC1LI2,MANBA,B4GALT5,SLC41A1,FAM76A,TKT,CBLL1,ARGLU1,LANCL1,POFUT1,FAM8A1,HEATR5B,HLA-A,EBP,RFWD3,NDUFA2,FJX1,FUT8,BTF3L4,PTPN11,MRPL54,FEM1B,RPL19,CNN2,NDUFA3,MTX2,MSH6,PDLIM2,LONRF3,RFXANK,FBXO9,GUF1,RPL32,ZHX1,OAZ2,NDUFS5,WDR91,HIGD2A,RORB,POLA2,ZNF76,MTX3,COPA,UQCR10,PHRF1,HMGXB3,ABCB10,COMMD5,DST,RAB35,GPATCH1,TCEA1,DRAM2,DEAF1,SNRNP200,LAP3,NCK1,VHL,SREK1,ARHGDIB,PITPNB,HSPB11,BRWD1,PPM1G,SH3GLB2,BAZ1B,ACBD4,STK11,CLU,CHEK2,ZSWIM3,TSTD2,MRPL13,CHPT1,DCAF5,CAPN1,UBE2D3,NSMCE4A,PPP1R12A,ZCCHC8,GORASP1,NACA,C19orf25,EPN1,PCSK7,THRAP3,QSOX2,TTF1,NUP205,PRPF18,CHKA,DTL,ZRANB1,SLC12A2,CSNK1G3,NUDT4,RPL6,VKORC1,SLTM,EVC2,KLHL15,SLC16A1,EHD4,SNRNP70,C11orf1,APOL2,N4BP2L2,CHMP2A,CORO7,FEZ2,PMS2,UCK2,UCK1,CLCC1,EXT2,MXD1,USP5,HNRNPA2B1,SAP130,NVL,PPP6C,CYB5R1,ZNF770,EBAG9,PCGF6,METTL2A,FAM72B,PON2,HNRNPR,HPS5,STAT6,MAPK1,BRD9,TMEM33,DNAJC2,TRIP12,SHPRH,SCYL1,VPS45,MYO9B,GFM2,SPPL2A,FASTKD3,FGFR3,PPIG,ZDHHC13,TMEM99,H2AFY,NDUFS8,ATG13,ERI3,FBL,FRMD8,SLC35A1,MICAL3,TGFB1,ELOVL5,HEMK1,TIMMDC1,HELB,PSPC1,MIER1,SCFD2,NDRG3,CDK11A,MTMR3,MEGF9,ACAT1,CENPT,PLOD3,RAB3IL1,ZSWIM6,RAB14,ADD1,KDM4A,MRPS15,XIAP,DHX8,GLUD1,PABPC4,CDK5,CALM2,PSMD1,NEK6,NSRP1,RABGAP1L,SRSF4,FNIP2,KCNAB2,PCBP2,PLK3,ZNF672,MRPL43,HSDL1,MCL1,PPFIA3,SMC2,ICMT,SLC50A1,STOML2,LIMK1,ZNF689,PRDX5,ATE1,MLYCD,ST3GAL2,ATP6V0C,FBXL3,E2F2,PFKP,AAAS,DDX42,SSRP1,MRPL9,MRPS2,STRN4,TOP2B,ZNRF3,DDRGK1,RAVER2,GNS,INTS7,INPP5A,MCM5,PHF14,ZNF326,UBE2QL1,NAGPA,TIMM8B,ETV3,TSPYL4,TSPAN31,DHX29,TEX10,MAN1B1,RPS10,CBFA2T2,ABCF1,RHOB,LRRC14B,DTWD1,PTPRF,SCARB2,OSBPL11,CCDC86,SLAIN1,MDH1,HEXA,RNF139,SNX14,ZNF296,TRERF1,UBR2,CHD1L,ACTR3,WDTC1,MYH9,CREBL2,PRKACA,SAFB2,ANKIB1,STAM,ARL6IP6,RAB21,SP100,ZKSCAN1,NUP107,ANKRD13C,MAVS,CEP63,TMEM136,ATF2,DCTN1,SHOC2,MAP4K4,WBP2,ATP6V0A1,NUSAP1,DNAJA1,NDUFA7,TAF2,C19orf54,SEC61A1,RPLP1,WDR7,CBLN2,FUS,GEN1,LRP8,COIL,LRCH1,ZNF786,RPS2,SESTD1,TRAK1,JMJD6,AKT1S1,KRI1,FBXO3,GATC,NDUFB4,PPP1R8,PRDM4,GTSE1,GEMIN6,DCP1A,SGCB,S100A6,IMPA2,NUDC,PDPK1,TK1,GUK1,TNFAIP3,GALC,ZNF512,KIAA0930,MRPS10,DDX39A,RPA1,ZNF180,ZNF862,KEAP1,POLE,TATDN2,PITX1,CAPN7,LRPPRC,PML,HMGB2,USF2,ANAPC4,SRM,DDX47,MCCC1,CDC42SE2,S1PR2,CDIPT,SEC16A,SSR1,LIN9,ZNF639,TRMU,ETV6,PIK3R2,TXLNA,PPCDC,FAM86C1,MYBL1,CCAR1,MRPL32,ABCC5,BAZ2A,PBXIP1,TLK1,MRPL12,EZR,LNX2,LRP5,BRCA1,PRKRA,STX16,EPB41,OPTN,SEPT1,SOCS4,QRSL1,PIEZO1,OSGEPL1,GLCCI1,NUDT11,NAA60,GEMIN7,SEPHS2,LZTR1,RACGAP1,PPP3CB,B4GALT4,RLF,RAPGEF6,SNRNP25,RB1,VASP,MED8,VMP1,PPIL2,MEA1,TIMELESS,AHDC1,ALDH18A1,TMEM8A,PREB,ABCC1,TRAPPC9,AACS,MEMO1,KRAS,RTF1,UBE4B,NFATC2IP,ARPC1A,ZNF174,PSMC4,GOLGA4,SYNCRIP,PALB2,PRPS2,NIPA1,TIGD2,RNF114,FOXM1,XAB2,SUMO2,DUSP22,CSDE1,MDM2,CORO1A,MINPP1,METTL9,POC5,DVL2,GM2A,PSMA8,COQ10B,TIGD5,SLC26A6,CYP20A1,PRPF3,TXNL4A,RPSA,SRSF1,DNAJC10,SCAP,ZNF700,PLEKHG4B,TIMM17A,TOMM6,LTA4H,AP2S1,USP53,INTS2,CTDP1,MIF4GD,CDT1,ARID5A,SUMF1,GGA2,CSNK1A1,AP3S1,RMI1,TFRC,PTPN2,STARD9,GSTK1,NDUFV1,SLC1A4,CWC27,SLC35B4,DDX31,ABCD1,RPAP3,CNTN5,SNX2,ZMYM5,CCDC34,CHCHD6,BSDC1,FBXO41,KPNA4,BIRC5,TFE3,SNAP29,CDCA7L,PKD2,ACADM,CHMP7,SAT2,ZNF496,TAP1,YTHDF3,NHLRC3,IKBIP,ELMOD2,KIFC1,DBNDD1,CYB5RL,PARPBP,RNASEK,CDC25B,DNMT1,NOL12,ORAI2,USO1,AKT2,NOL8,AURKB,MCFD2,SLC25A5,ZFAND5,MAK16,STT3A,TMED10,PSMD8,EIF2D,ITGB1,PTPN7,RRS1,ARRB2,RTN3,ZNF598,DDX58,WSB2,PPIB,MUT,GMFG,HLA-E,NDUFA4,MAN2B1,METTL3,CFLAR,NDUFS4,RNF121,MEX3C,KLF16,HDAC7,DAD1,BDH1,PCYT2,GNAI2,ANKHD1,TERF2,MORC3,KCTD20,SEPT8,DCTD,PKM,TOMM40,PATL1,ADSS,SERTAD2,SERF2,ZFP92,NSF,DCK,ERGIC3,ACLY,LPCAT4,VCPIP1,PPP6R3,PPP6R2,MAP3K5,YY1,CDK2,RNF14,ZC3HAV1,SYS1,ZBTB37,URB2,EIF3D,MAGED1,KLHL18,ADPGK,SLC25A44,AP1B1,SDHA,PAIP2,PHC2,CRKL,MOAP1,TERF2IP,ZNF75D,SHC1,UCHL5,NAA35,TMBIM1,CDKN2AIP,CCT2,MKLN1,LYRM1,GALK2,CDC23,SHCBP1,AP4E1,PRDM11,VEZF1,PPP2R5A,ACYP1,STAT1,PPA2,TRIM32,RHEBL1,R3HCC1L,C1orf112,TCF3,MRI1,BRAP,AGPAT3,MYNN,SPR,RAB11A,REEP5,FOXO3,MAD2L2,CCDC28A,RBM17,MAT2B,PTEN,CENPJ,TAGLN2,NCOA2,PACS2,SMC4,RNASEH2C,NEK7,NET1,PARP4,TBRG4,ANAPC2,RPL27A,YIF1A,SGSH,HGS,TTLL4,SLC38A7,MFAP1,CCDC69,BRWD3,ESYT2,SKA3,NPHP4,UBE2E2,HNRNPAB,PLXNC1,ST13,TMEM184B,DNAJC24,ZNF107,SLC29A1,KIF2C,AGFG1,SIRT2,USP48,UBQLN2,FKBP2,EDC3,UBLCP1,ZNF804A,RAP1A,THADA,EIF4A3,ATG3,DPYSL2,PPP1R12C,AKR1B1,JOSD1,NDUFB9,RP2,TTC4,TECR,ARID4A,FGFR1OP2,TIMM50,TDP1,DPM1,FOPNL,SLC16A7,SLC25A22,STK17B,DHX15,CHAF1A,GEMIN5,COPS6,SASS6,PSMC1,SLC12A7,TBC1D12,TM9SF4,ZNF768,UFC1,MED13L,TIA1,MEF2A,EPHX2,PITHD1,RHBDD1,NFATC3,BUD31,ZNF335,YBX1,KNTC1,UBE3C,ACAD8,ZNF189,ALDH9A1,KDELR1,TSTA3,CIC,OXR1,SEPT7,NAP1L1,ODF2,EXOC4,NUP62,PITPNA,KIAA1328,NAA20,PTDSS1,PDSS2,C7orf26,TMEM106C,IMMT,ASH1L,CHERP,WDYHV1,PLAGL2,IRF3,CHKB,TWF2,ANKRD28,FARSA,ANKLE1,APOOL,PDIA6,ACSL5,TOR1AIP2,AZI2,RAD54B,DAP3,ZNF317,AKNA,REEP4,CBX4,KIF3B,GOLPH3L,SH2D3A,CASP6,TOR3A,SRGN,DBF4,MFSD10,SAC3D1,CTNNBL1,YIF1B,CLDND1,TTC17,SLC25A1,GINS1,PAQR6,CSNK1G2,TELO2,ADAM17,HMGN1,NASP,ASPM,PPP1R21,PRKAR1B,SYMPK,TARS,SNRPA,MAPK3,HSPA1B,HLA-B,ATAD2,PLAA,ZNF330,OSBPL8,KBTBD7,PREPL |
| 7.936e-03 | -4.84 | GSE11057_PBMC_VS_MEM_CD4_TCELL_DN | MSigDB lists | GSE11057_PBMC_VS_MEM_CD4_TCELL_DN | 176 | 39 | 17377 | 2626 |
HECA,LIME1,CASP6,ANKH,SLC39A13,SYNRG,GSTK1,ATIC,KIF22,TECR,MAP3K14,RHBDD2,FAM171A1,CAMK2G,LDHB,SPTAN1,NIPAL3,VOPP1,CYTH1,DDX24,TSPYL4,PBXIP1,ITM2A,ESYT1,EML4,PRIM1,EPB41,OPTN,ZNF862,SEPT1,GOLGA7,HINT1,ITGB1,PRMT7,USP20,ZFP90,TRAF5,TMEM14A,MZT2B |
| 7.937e-03 | -4.84 | APC/C:Cdc20 mediated degradation of Cyclin B | REACTOME pathways | R-HSA-174048 | 23 | 9 | 10287 | 1696 |
CDC16,CDC27,RPS27A,ANAPC2,ANAPC7,CCNB1,CDC23,UBE2C,ANAPC4 |
| 7.952e-03 | -4.83 | NXF2 (nuclear RNA export factor 2) | protein interactions | 56001 | 62 | 18 | 17029 | 2761 |
YTHDC1,FYTTD1,ASH1L,NXT1,ZNF445,SUGP2,YTHDC2,BORA,APP,UPF1,NUP62,NUP153,GLE1,CSNK1D,N4BP2L2,DVL2,ZC3HAV1,NXT2 |
| 7.952e-03 | -4.83 | SLC3A2 (solute carrier family 3 member 2) | protein interactions | 6520 | 62 | 18 | 17029 | 2761 |
CYLD,ATXN3,VHL,CUL3,TMEM216,PKM,MCM2,VDAC1,CDC73,GSTK1,ATP2A2,E2F4,ITGB1,TRA2B,MBOAT1,SRSF3,GNAI2,ATF2 |
| 7.952e-03 | -4.83 | CHD1L (chromodomain helicase DNA binding protein 1 like) | protein interactions | 9557 | 62 | 18 | 17029 | 2761 |
PLK1,H2AFZ,PRKDC,SCYL1,TGOLN2,RFC2,API5,GLMP,RPA1,XRCC5,SUPT16H,CBX3,FAS,RPA2,H2AFX,SRPK2,CDC5L,SSRP1 |
| 7.952e-03 | -4.83 | PPP6R1 (protein phosphatase 6 regulatory subunit 1) | protein interactions | 22870 | 62 | 18 | 17029 | 2761 |
FOXK1,PRKDC,ACSL3,USP10,BRCA1,DCLRE1C,ANKRD28,PFDN5,HSPA4,HADHB,PPP6C,PDCD2,ARHGEF2,KNTC1,MOB1A,PPP6R3,PPP6R2,C2CD5 |
| 7.977e-03 | -4.83 | TGTGTGA,MIR-377 | MSigDB lists | TGTGTGA,MIR-377 | 187 | 41 | 17377 | 2626 |
MAX,TRIP12,STRN4,XIAP,DLGAP4,CUL1,CTCF,SUMF1,CREBL2,ARGLU1,BCL2L1,ETS1,ARID1B,MDM2,THADA,JAZF1,GRSF1,FUT8,CDKN1B,NUP153,SLC35C2,TMX1,TMED2,SRPK2,BAZ2A,C16orf72,MIER1,ATXN1,FAM133B,ARID1A,MACF1,ARMC8,PHF6,SRSF1,KIF2A,SUGP1,ATXN2L,RNF38,VCPIP1,NCOA1,PRPF4B |
| 7.977e-03 | -4.83 | GSE22886_NAIVE_BCELL_VS_BM_PLASMA_CELL_DN | MSigDB lists | GSE22886_NAIVE_BCELL_VS_BM_PLASMA_CELL_DN | 187 | 41 | 17377 | 2626 |
SRM,GLT8D1,MAGEH1,LIME1,TOR3A,SRGN,NENF,CLCC1,SLC35B1,B4GALT4,ABHD14A,LMNA,CFLAR,MAN1A1,RPN1,SLC1A4,UBA5,RRBP1,CITED2,TFG,LRRC59,ASB6,KDELR1,PREB,TMEM115,TIMP2,VKORC1,NEU1,OPTN,TRAM2,UAP1,ORMDL2,STT3A,TONSL,NAGLU,IMPDH1,SIL1,PDXK,B4GALT3,EHD4,RTN3 |
| 7.977e-03 | -4.83 | GSE33513_TCF7_KO_VS_HET_EARLY_THYMIC_PROGENITOR_DN | MSigDB lists | GSE33513_TCF7_KO_VS_HET_EARLY_THYMIC_PROGENITOR_DN | 187 | 41 | 17377 | 2626 |
RHOG,PIGM,PIGN,FAM53C,SLC2A1,TMX3,SNN,EIF1B,ABHD14A,FAM192A,TFAP4,SUB1,ADD3,GLIS2,EFCAB11,MRPL34,H2AFY,MAST2,CORO1A,ACAD8,ZNRD1,CGGBP1,POLR2G,NET1,HELB,TYW1,POLR2D,UHRF1BP1,EIF2A,POLG2,GLOD4,AGPAT2,SCAP,PSMD3,BAZ1B,TRIM32,RGL1,SASS6,BRD9,E2F2,RPS26 |
| 7.977e-03 | -4.83 | GSE17721_CTRL_VS_PAM3CSK4_6H_BMDC_UP | MSigDB lists | GSE17721_CTRL_VS_PAM3CSK4_6H_BMDC_UP | 187 | 41 | 17377 | 2626 |
TMEM203,MANBA,GNE,UBXN1,CUTA,DNAJB1,HCFC1R1,LCLAT1,C19orf48,XPR1,C14orf119,CDK5,CDKN2C,SMC3,RPAP1,MGAT5,IMPA2,ELOF1,PTPN18,LAP3,NEK7,KIAA0930,POLR3GL,HTATIP2,SLC50A1,BTBD1,ASF1B,NUCB1,RPS14,ERGIC3,NFIL3,PRPS2,PML,USP20,ATF6,MDH1,RUFY3,FAU,CCNB2,MYL12B,FAF1 |
| 7.977e-03 | -4.83 | GSE36888_UNTREATED_VS_IL2_TREATED_TCELL_17H_UP | MSigDB lists | GSE36888_UNTREATED_VS_IL2_TREATED_TCELL_17H_UP | 187 | 41 | 17377 | 2626 |
ZBED3,MIF4GD,REPS2,MEF2A,NDUFA4,STMN1,ITGB5,ZADH2,ABHD14A,PABPC4,NUDT19,PCNA,GRSF1,MDFIC,KIF22,TECR,SPTSSA,RNF135,TPCN1,HDHD2,CDKN2AIP,TIMP2,ZFP64,PPT1,MAP4K3,CADM1,CAT,C19orf54,PLD3,PFDN5,HHEX,PON2,SCARB2,PRPS2,WDR7,ACADM,CHEK2,PREPL,NANP,WDR91,HEXA |
| 7.977e-03 | -4.83 | GSE19941_UNSTIM_VS_LPS_AND_IL10_STIM_IL10_KO_NFKBP50_KO_MACROPHAGE_DN | MSigDB lists | GSE19941_UNSTIM_VS_LPS_AND_IL10_STIM_IL10_KO_NFKBP50_KO_MACROPHAGE_DN | 187 | 41 | 17377 | 2626 |
PARP12,ANXA6,DYNLL1,DBF4,RRM1,AGFG1,UBE2I,RPL11,RAD23A,ERH,NUP210,SUV39H2,ATG3,CYB5RL,SIVA1,PHTF1,MSH2,TAP2,PRADC1,MINPP1,MCMBP,STRAP,TRIM14,ZMYND11,ERLIN1,EZR,BRCA1,FKBP3,MTMR3,TRIM47,L3MBTL3,OSBPL8,PPA2,H2AFX,RNASEL,SMPD4,NAA20,NDE1,OAZ1,FAM83G,AAAS |
| 7.977e-03 | -4.83 | GSE14769_UNSTIM_VS_60MIN_LPS_BMDM_DN | MSigDB lists | GSE14769_UNSTIM_VS_60MIN_LPS_BMDM_DN | 187 | 41 | 17377 | 2626 |
IER2,B4GALT5,SRGN,ARID5A,MXD1,RNF103,CFLAR,TNS3,MEX3C,ARHGEF2,CLDND1,CITED2,TIPARP,ZNF800,RYBP,IFRD1,BIRC3,ETV3,TMEM39A,ANKRD33B,BTG2,ACSL3,MTMR12,FAM133B,MCL1,ODC1,KLF6,ZFAND5,PICALM,DHX15,NCDN,HSPA1B,SOCS7,HLA-B,UAP1,GADD45B,SIAH2,DDX5,HMGB2,TOB1,FAM72A |
| 7.977e-03 | -4.83 | GSE44649_WT_VS_MIR155_KO_ACTIVATED_CD8_TCELL_UP | MSigDB lists | GSE44649_WT_VS_MIR155_KO_ACTIVATED_CD8_TCELL_UP | 187 | 41 | 17377 | 2626 |
SART1,ZBTB10,MIF4GD,AGRN,TRIP10,TAP1,VTI1A,GYG1,SNN,KTN1,RGS1,CFLAR,TMCC3,PTPN2,IRF4,CLIC4,PRDM4,TPST1,TAP2,LRSAM1,PPA1,PACS2,SPTAN1,IFRD1,TRAFD1,ETV3,TMEM39A,ATP6V0A1,ANAPC2,OGFR,PRMT2,SLTM,FAS,JAK1,NFIL3,BBX,NLRC5,ADAM9,NAA20,PPP2R2D,RNF114 |
| 7.977e-03 | -4.83 | GSE17721_POLYIC_VS_PAM3CSK4_16H_BMDC_UP | MSigDB lists | GSE17721_POLYIC_VS_PAM3CSK4_16H_BMDC_UP | 187 | 41 | 17377 | 2626 |
ASH1L,CDS2,TMEM184B,RRAGC,IL21R,CUTC,CMTM6,MXD1,SPPL2A,TMCC3,RAB8A,PDCD10,HDAC7,MTA1,ETV6,RPAP1,ZFYVE27,ALDH18A1,MVP,TFG,RBM15,TIPARP,MORC3,VOPP1,AGGF1,TIMP2,NASP,PRRC2A,RCOR1,IL12RB1,PLEKHF2,PI4K2A,BRMS1,GPS2,DCAF11,RBMS1,HMGB2,NAA20,NRBP1,STARD3NL,PRPF4B |
| 7.977e-03 | -4.83 | GSE42021_CD24HI_VS_CD24LOW_TCONV_THYMUS_DN | MSigDB lists | GSE42021_CD24HI_VS_CD24LOW_TCONV_THYMUS_DN | 187 | 41 | 17377 | 2626 |
DDX58,CYLD,MAX,HLA-E,TAP1,BTN3A1,ADPGK,METTL3,RMI1,HLA-A,CREM,GSTK1,PSMA6,CTSS,ZNF302,LPIN2,NUP107,TAP2,TFG,STAT3,TRAFD1,USO1,TNFAIP3,GUK1,LAP3,ASPM,ERLIN1,COQ10B,ACSL3,SLC25A22,MCL1,PSMB9,KLF6,RHBDF2,PLEKHF2,FAS,OPTN,KIF2A,RBMS1,APOL2,RNF114 |
| 7.977e-03 | -4.83 | GSE4142_NAIVE_BCELL_VS_PLASMA_CELL_UP | MSigDB lists | GSE4142_NAIVE_BCELL_VS_PLASMA_CELL_UP | 187 | 41 | 17377 | 2626 |
KIF3B,TMEM184B,UGP2,WDYHV1,SESTD1,TSC22D3,TRAK1,MEF2A,EZH1,DAZAP2,RCOR3,MIEN1,APP,CCDC28A,MED10,FAM89B,PHKG2,ABI1,GM2A,CGGBP1,CAMK2G,NIPAL3,PHF20L1,USO1,SEPT9,MAP4K4,USP22,CBFA2T2,STX16,ARSK,ERC1,PI4K2A,MBIP,SCARB2,GOLGA2,ACOX1,HAGHL,ZFP90,MBD6,FBXL3,ZBTB24 |
| 7.977e-03 | -4.83 | GSE4142_NAIVE_VS_GC_BCELL_UP | MSigDB lists | GSE4142_NAIVE_VS_GC_BCELL_UP | 187 | 41 | 17377 | 2626 |
BCL2L12,CDS2,WDYHV1,SESTD1,CERK,MYH9,PXMP2,CHKB,INO80E,DCUN1D4,PRNP,APLP2,LHX8,LRRC8D,TBC1D14,PHF14,SLC44A1,AFF1,FBXL7,MDFIC,PHKG2,MGAT5,TMEM14C,ULK3,KLF10,TACC1,JTB,RAB3IP,RIT1,NUTF2,SOX4,DDX23,CHD3,RAB24,TATDN2,WNT5B,ARNTL,KBTBD7,RGL1,CHPF2,TMEM131 |
| 7.977e-03 | -4.83 | GSE20715_WT_VS_TLR4_KO_48H_OZONE_LUNG_UP | MSigDB lists | GSE20715_WT_VS_TLR4_KO_48H_OZONE_LUNG_UP | 187 | 41 | 17377 | 2626 |
TCF12,HSPH1,FLYWCH2,CAST,TSC22D3,FAM129A,MEF2A,SLC29A1,DNAJB1,GGA2,PSEN1,ARL6IP6,PAPOLA,FBXO3,FANCL,HOMER1,CLIC4,AHSA1,CRY2,TAGLN2,FRMD8,RYBP,SGCE,ABCF2,CADM1,DNAJA1,ESYT1,FXR1,PLEKHF2,HSPA1B,RAB18,NEK1,LTBP4,TWSG1,SNAP29,LMBR1,FKBP5,WIPI2,NDE1,NAA60,PRPF4B |
| 7.977e-03 | -4.83 | GSE22033_UNTREATED_VS_MRL24_TREATED_MEF_DN | MSigDB lists | GSE22033_UNTREATED_VS_MRL24_TREATED_MEF_DN | 187 | 41 | 17377 | 2626 |
REPS2,MYH9,UBE2Z,AGFG1,RAPGEF6,CFLAR,FBRS,TET3,CAPN2,IRF4,APLP2,MDM2,PPME1,PHF14,AKAP8,DCP1A,AP2B1,ECD,TP53BP2,TFG,STAT3,ZNF189,PPIF,RHOBTB3,RB1CC1,BTG2,ZNF202,PFKFB3,TOPORS,SRSF5,RAB1A,RAB22A,EML4,RHEB,SH3BP5,CSNK1G1,CTBS,ITGB1,USP11,FAM208A,LONP2 |
| 7.979e-03 | -4.83 | breast-carcinoma-lobular_carcinoma | COSMIC cancer mutations | breast-carcinoma-lobular_carcinoma | 771 | 139 | 17385 | 2587 |
TSC2,NF1,CSNK2A1,MAPK14,EEF2K,CDKN2C,CDK5,ABL2,NEK6,ETV6,DNMT1,SRPK2,PLK1,PLK3,NRAS,CELSR2,AKT2,VHL,PBK,TLK1,CDC6,MCL1,PPFIA3,AURKB,BRCA1,STX16,STK17B,DOT1L,MAP3K4,AHNAK,SMAD2,RBM47,CHD3,LIMK1,AXIN1,OGT,STK11,RNASEL,CHEK2,CENPF,PRKAA1,TRIO,CDK13,ADCK5,PPP3CB,EIF2AK4,RB1,CEP104,MSH2,DAPK1,CTR9,BCL2,PHKG2,CSNK1G3,CARS2,EIF5A,EMB,ITM2A,MAP4K3,EIF2AK1,KRAS,ARID1A,MAP2K2,DAPK3,MASTL,GNAS,TSC1,EPRS,GOLGA4,RBM25,PALB2,MAP3K5,CDK2,NRBP1,CDKN2A,DNMT3A,TP53RK,RAF1,RPS6KA1,SMARCA4,BCL2L1,PRKACA,LYN,TWF2,GGPS1,LCLAT1,CRKL,CSDE1,SAP130,PRKD3,PDK2,MDM2,MAVS,RNASEH2A,CDK12,SCYL3,CPNE1,BRD4,MAP4K4,PKMYT1,GSTCD,TRIM28,JAK1,CLK3,FASTK,HIPK2,STK38,WDR59,TRIM32,MAPK1,SMAD4,PRPF4B,SCYL1,CSNK1A1,SCYL2,FGFR3,PTEN,PTPN11,STAT3,MSH6,CAMK2G,PDPK1,SAMD4B,CSNK1G2,HMGN1,TNFAIP3,NEK7,PNPLA8,MEN1,COMMD4,MARK2,MAPK3,INF2,STX18,MAPK6,RPS6KC1,HRAS,HIPK3,SSSCA1 |
| 7.979e-03 | -4.83 | lobular_carcinoma | COSMIC cancer mutations | lobular_carcinoma | 771 | 139 | 17385 | 2587 |
TSC2,NF1,CSNK2A1,MAPK14,EEF2K,CDKN2C,CDK5,ABL2,NEK6,ETV6,DNMT1,SRPK2,PLK1,PLK3,NRAS,CELSR2,AKT2,VHL,PBK,TLK1,CDC6,MCL1,PPFIA3,AURKB,BRCA1,STX16,STK17B,DOT1L,MAP3K4,AHNAK,SMAD2,RBM47,CHD3,LIMK1,AXIN1,OGT,STK11,RNASEL,CHEK2,CENPF,PRKAA1,TRIO,CDK13,ADCK5,PPP3CB,EIF2AK4,RB1,CEP104,MSH2,DAPK1,CTR9,BCL2,PHKG2,CSNK1G3,CARS2,EIF5A,EMB,ITM2A,MAP4K3,EIF2AK1,KRAS,ARID1A,MAP2K2,DAPK3,MASTL,GNAS,TSC1,EPRS,GOLGA4,RBM25,PALB2,MAP3K5,CDK2,NRBP1,CDKN2A,DNMT3A,TP53RK,RAF1,RPS6KA1,SMARCA4,BCL2L1,PRKACA,LYN,TWF2,GGPS1,LCLAT1,CRKL,CSDE1,SAP130,PRKD3,PDK2,MDM2,MAVS,RNASEH2A,CDK12,SCYL3,CPNE1,BRD4,MAP4K4,PKMYT1,GSTCD,TRIM28,JAK1,CLK3,FASTK,HIPK2,STK38,WDR59,TRIM32,MAPK1,SMAD4,PRPF4B,SCYL1,CSNK1A1,SCYL2,FGFR3,PTEN,PTPN11,STAT3,MSH6,CAMK2G,PDPK1,SAMD4B,CSNK1G2,HMGN1,TNFAIP3,NEK7,PNPLA8,MEN1,COMMD4,MARK2,MAPK3,INF2,STX18,MAPK6,RPS6KC1,HRAS,HIPK3,SSSCA1 |
| 7.994e-03 | -4.83 | acetyltransferase activity | molecular function | GO:0016407 | 105 | 26 | 17224 | 2647 |
GNPNAT1,KAT2A,KAT7,ELP4,EDF1,TAF6L,USP22,WDR5,SUPT7L,TEX30,CRAT,LPCAT4,OGT,NAA50,ACAT1,TAF5L,KANSL2,TAF12,NCOA1,NAA20,ATF2,SMARCE1,LPCAT1,NAA35,SAT2,NAA60 |
| 8.002e-03 | -4.83 | cellular response to decreased oxygen levels | biological process | GO:0036294 | 197 | 43 | 17256 | 2622 |
UBE2D3,DNMT3A,PHB2,PRKAA1,SIRT2,SLC29A1,CCNB1,PSMD9,FOXO3,LMNA,EEF2K,CFLAR,PSMD2,CCNA2,PSMA6,MDM2,PSMD1,SUV39H2,TIGAR,PTEN,BCL2,CITED2,HP1BP3,PLK3,RBX1,PSMA8,VHL,ERO1A,PSMB7,PSMA1,PSMB9,PSMB3,PSMC4,TSC1,RPS27A,PSMD8,PSMD3,HIPK2,E2F1,RBPJ,PSMC1,CPEB2,EGLN1 |
| 8.003e-03 | -4.83 | GSE4590_PRE_BCELL_VS_LARGE_PRE_BCELL_DN | MSigDB lists | GSE4590_PRE_BCELL_VS_LARGE_PRE_BCELL_DN | 149 | 34 | 17377 | 2626 |
MIB2,KCTD7,DNAJC5,GOLPH3L,UCK1,NHLRC3,CDIPT,EIF1B,ASXL2,FOXO3,TRIM65,PAIP1,XPR1,SAC3D1,GTPBP3,KDM2A,HDAC7,PPP1R12C,FBXW2,RNF169,LDHB,PLK3,RPRD1A,PSMA8,AACS,THNSL1,PCGF1,TTC33,CCDC127,PWWP2B,CACNB1,AGPAT2,DUS3L,MLYCD |
| 8.003e-03 | -4.83 | GSE14386_UNTREATED_VS_IFNA_TREATED_ACT_PBMC_MS_PATIENT_DN | MSigDB lists | GSE14386_UNTREATED_VS_IFNA_TREATED_ACT_PBMC_MS_PATIENT_DN | 149 | 34 | 17377 | 2626 |
DDX58,IER2,PARP12,TMBIM4,NHLRC3,PMF1,ORC1,PPP1R16B,LCLAT1,TUBGCP2,MXD1,SLC25A36,IRF4,RABGAP1L,IL6ST,MDFIC,STAT3,RPAP3,BIRC3,PBK,CYP20A1,ITM2A,BRCA1,TRAM2,KIF18A,ETS2,TWSG1,HIPK2,NFIL3,FAM3C,SOCS4,ADAM9,TFDP2,CABLES1 |
| 8.003e-03 | -4.83 | GSE13547_WT_VS_ZFX_KO_BCELL_ANTI_IGM_STIM_2H_DN | MSigDB lists | GSE13547_WT_VS_ZFX_KO_BCELL_ANTI_IGM_STIM_2H_DN | 149 | 34 | 17377 | 2626 |
SYS1,TSC22D3,CHCHD2,JMJD6,CREBL2,ABHD14B,EZH1,NDUFS7,SLC25A36,FASTKD3,ZNHIT6,PIK3IP1,NFU1,PTGES3,ZNRD1,EBAG9,FYTTD1,DDX24,AATF,COQ10B,MBLAC2,BTG2,AMD1,ITM2A,ICAM2,TANC1,HERPUD2,VKORC1,SETD3,NFIL3,PDCD2L,TOB1,SMNDC1,TMEM33 |
| 8.003e-03 | -4.83 | LU_AGING_BRAIN_DN | MSigDB lists | LU_AGING_BRAIN_DN | 149 | 34 | 17377 | 2626 |
CDC40,ENSA,C5orf30,TOP2B,TGOLN2,RAB6A,RAD23A,FKBP1A,CALM2,NAPG,ATP2A2,MEGF8,CORO1A,CLTB,UBE2M,SRSF10,GORASP2,NUTF2,PITPNB,RAB1A,VDAC1,MAT2A,PLD3,BRD2,ETS2,DUSP3,E2F4,TIMM17A,OGT,PPP3R1,PITPNA,YWHAZ,RBBP4,MAPK1 |
| 8.010e-03 | -4.83 | amino sugar biosynthetic process | biological process | GO:0046349 | 13 | 6 | 17256 | 2622 |
AMDHD2,UAP1,NANP,GNPNAT1,GNPDA1,GNE |
| 8.010e-03 | -4.83 | protein localization to phagophore assembly site | biological process | GO:0034497 | 13 | 6 | 17256 | 2622 |
ATG13,WIPI2,ATG9A,WDR45B,PACS2,MFN2 |
| 8.010e-03 | -4.83 | pyrimidine-containing compound salvage | biological process | GO:0008655 | 13 | 6 | 17256 | 2622 |
UPRT,UCK1,TK1,DCK,HDDC2,UCK2 |
| 8.014e-03 | -4.83 | Nanoparticle triggered autophagic cell death | WikiPathways | WP2509 | 24 | 9 | 5312 | 837 |
TSC1,TSC2,VMP1,ATG3,BCL2,BECN1,SH3GLB1,ATG4A,CHAF1A |
| 8.016e-03 | -4.83 | OB_NTP_bind | pfam domains | PF07717 | 17 | 7 | 17054 | 2545 |
DHX8,DHX16,DHX29,DHX15,YTHDC2,DHX57,DHX9 |
| 8.028e-03 | -4.82 | AATK (apoptosis associated tyrosine kinase) | protein interactions | 9625 | 53 | 16 | 17029 | 2761 |
PPP3CA,PTPN18,DPM1,PTEN,PTPN7,PTPN11,MTMR6,SLC25A12,SLC25A22,CDC25B,PPP3CB,PTPDC1,DNAJA1,ILKAP,EYA2,SLC25A1 |
| 8.028e-03 | -4.82 | RNF114 (ring finger protein 114) | protein interactions | 55905 | 53 | 16 | 17029 | 2761 |
UBE2D3,UBE2E2,USO1,EWSR1,PARP12,TNFAIP3,SUZ12,LAGE3,RPSA,MAPK3,UEVLD,RNF38,TRIM52,MAVS,SMURF1,RNF114 |
| 8.028e-03 | -4.82 | RECQL5 (RecQ like helicase 5) | protein interactions | 9400 | 53 | 16 | 17029 | 2761 |
PLK1,POLR2I,POLR2G,DHX29,PRKDC,TOP3A,POLR2D,BRCA1,PITHD1,POLR2A,WWP2,PCNA,EIF2D,CREB1,RPRD1B,DDX42 |
| 8.028e-03 | -4.82 | PPARD (peroxisome proliferator activated receptor delta) | protein interactions | 5467 | 53 | 16 | 17029 | 2761 |
NCOR2,NSMCE4A,TRMT6,GADD45G,PSMG1,ITGB5,RXRB,MDM2,DUT,HDAC7,GADD45B,STAT1,NCOA1,STAT3,HDAC2,NCOA2 |
| 8.028e-03 | -4.82 | HLTF (helicase like transcription factor) | protein interactions | 6596 | 53 | 16 | 17029 | 2761 |
DTL,RPA2,SP3,USP7,PCNA,EWSR1,RAD18,SHPRH,CHD1L,CERK,RPAP1,UBE2Z,NFATC2,BRCA1,RPA1,CDC5L |
| 8.028e-03 | -4.82 | TAF4 (TATA-box binding protein associated factor 4) | protein interactions | 6874 | 53 | 16 | 17029 | 2761 |
TCF12,EWSR1,KAT2A,CDC23,CREM,CBX3,TAF2,CDC16,CDC27,TBPL1,ANAPC7,KIFAP3,TAF12,NAP1L4,CREB1,TAF6 |
| 8.028e-03 | -4.82 | AGL (amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase) | protein interactions | 178 | 53 | 16 | 17029 | 2761 |
SDHB,CAT,ADSS,FKBP1A,PRKAB1,SP100,AHSA1,CUL3,CUL1,GLO1,BRCA1,MAN2B1,MCFD2,PKM,VPS25,USP5 |
| 8.029e-03 | -4.82 | G-patch | pfam domains | PF01585 | 21 | 8 | 17054 | 2545 |
SUGP1,GPATCH1,RBM17,NKRF,AGGF1,CHERP,SUGP2,GPATCH4 |
| 8.030e-03 | -4.82 | HMG20A (high mobility group 20A) | protein interactions | 10363 | 95 | 25 | 17029 | 2761 |
CCDC93,MAX,RPRD1A,ADD1,MTA2,BRAP,RCOR1,NUF2,UHRF1BP1,PAWR,PSMD9,RCOR3,GIT2,HMG20A,OIP5,CCNK,GRIPAP1,RABGAP1L,MBD2,PHF14,ARNTL,KPNA2,SMAD4,HDAC2,HP1BP3 |
| 8.032e-03 | -4.82 | ZHENG_GLIOBLASTOMA_PLASTICITY_UP | MSigDB lists | ZHENG_GLIOBLASTOMA_PLASTICITY_UP | 237 | 50 | 17377 | 2626 |
CLSPN,CDT1,DBF4,CDCA3,RRM1,CDCA8,TPX2,KIF23,RACGAP1,NUF2,CCNB1,LYN,SPAG5,FZD6,GOLM1,DECR1,SNX18,UCHL5,DUT,MCM5,PRC1,NUP107,KIF22,PLK1,TK1,NASP,ASPM,RAD51AP1,ACSL3,PRKAR1B,RRM2,NUSAP1,AURKB,SMC2,CCNF,MCM2,ANLN,SHCBP1,DDX39A,NCDN,MTHFD2,KIF18A,POLE,BIRC5,RBL1,ZNF367,CLU,CCNB2,CDKN2A,PFKP |
| 8.048e-03 | -4.82 | phosphatase activity | molecular function | GO:0016791 | 272 | 57 | 17224 | 2647 |
CTDP1,EYA1,PTP4A3,CYCS,PPP3CB,EPHX2,DUSP22,PLPP5,UBLCP1,PTPN2,PPP1R3B,PDXP,TIGAR,PTEN,INPP5A,NT5DC1,MTMR4,IMPAD1,LPIN2,PPP4R1,PPP6C,PTPN11,CDC25B,MINPP1,PIKFYVE,HDHD2,CTDSP2,ILKAP,IMPA2,CAMK2G,TIMM50,PTPRK,NTPCR,PPP3CA,PTPN18,ACP2,MTMR6,PFKFB3,STYXL1,PTPRF,MTMR3,PPP2CA,ATP1A1,PPP2R5A,DUSP3,NT5C3B,PPM1G,PPA2,PTPN7,PPP3R1,DUSP11,PTPDC1,PLPP6,PPP5C,NANP,EYA2,PPP2R2D |
| 8.051e-03 | -4.82 | MAPK Signaling Pathway | WikiPathways | WP382 | 170 | 39 | 5312 | 837 |
MAX,CASP6,NF1,RAF1,RAC1,LAMTOR3,PPP3CB,STMN1,PRKACA,MAPK14,CRKL,RAP1A,CDC42,CDC25B,MAP3K14,ATF2,TGFB1,PPP3CA,NRAS,AKT2,TAOK1,MAP4K4,MAP4K3,KRAS,ELK1,MAP2K2,MAPK3,FAS,MAP3K4,GNA12,MKNK1,TAB2,MAPK6,PTPN7,PPP3R1,MAP3K5,PPP5C,ARRB2,MAPK1 |
| 8.059e-03 | -4.82 | protein acetyltransferase complex | cellular component | GO:0031248 | 93 | 23 | 18223 | 2701 |
KAT2A,KAT7,ELP4,SUPT20H,TAF6L,USP22,WDR5,SUPT7L,MEAF6,TAF2,MBIP,BRPF3,OGT,NAA50,KANSL2,ACTB,TAF5L,RUVBL2,TAF12,NAA20,TAF6,SGF29,NAA35 |
| 8.059e-03 | -4.82 | acetyltransferase complex | cellular component | GO:1902493 | 93 | 23 | 18223 | 2701 |
KAT2A,KAT7,ELP4,SUPT20H,TAF6L,USP22,WDR5,SUPT7L,MEAF6,TAF2,MBIP,BRPF3,OGT,NAA50,KANSL2,ACTB,TAF5L,RUVBL2,TAF12,NAA20,TAF6,SGF29,NAA35 |
| 8.077e-03 | -4.82 | protein K63-linked deubiquitination | biological process | GO:0070536 | 29 | 10 | 17256 | 2622 |
OTUD5,BABAM2,CYLD,ATXN3,TNFAIP3,ABRAXAS2,BABAM1,USP20,ZRANB1,USP13 |
| 8.077e-03 | -4.82 | protein K48-linked deubiquitination | biological process | GO:0071108 | 29 | 10 | 17256 | 2622 |
USP7,OTUD5,CYLD,ATXN3,TNFAIP3,USP20,VCPIP1,OTUD3,USP5,USP34 |
| 8.077e-03 | -4.82 | intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator | biological process | GO:0042771 | 29 | 10 | 17256 | 2622 |
PGAP2,HIPK2,TMEM109,CDIP1,MSH2,PML,AEN,TOPORS,CHEK2,IFI16 |
| 8.077e-03 | -4.82 | cristae formation | biological process | GO:0042407 | 29 | 10 | 17256 | 2622 |
CHCHD3,IMMT,ATP5MC3,ATP5F1B,ATP5F1A,APOOL,ATP5MF,TAZ,ATP5PF,CHCHD6 |
| 8.077e-03 | -4.82 | ATAD3A (ATPase family, AAA domain containing 3A) | protein interactions | 55210 | 76 | 21 | 17029 | 2761 |
COX15,CYLD,PHB2,SUZ12,PMS2,CUL3,CUL1,PTP4A3,NDUFA4,MCM2,VDAC1,TUBGCP2,NDUFS4,SSR1,RPN1,MEX3C,ZNF746,CYC1,MAP3K5,PHKG2,POC5 |
| 8.077e-03 | -4.82 | PSMD5 (proteasome 26S subunit, non-ATPase 5) | protein interactions | 5711 | 76 | 21 | 17029 | 2761 |
PMS2,PSMB7,PSMA1,PSMD9,MACF1,PSMB9,APP,PSMB3,PSMC4,RAD23A,PSMD2,PSMA6,KIF18A,PSMD1,PSMD8,PSMD3,PPME1,UHRF2,KIFAP3,PSMC1,GCSH |
| 8.077e-03 | -4.82 | PFDN5 (prefoldin subunit 5) | protein interactions | 5204 | 76 | 21 | 17029 | 2761 |
PPP3CA,PPP1R12A,POC1A,NSUN2,GLRX3,CCT8,TRIM28,GNB2,PSMC4,RPA1,BRMS1,IARS,PFDN4,PSMD8,PRPF4,PPP6R2,PDIA6,PPP6R1,RPRD1B,DCAF5,MLST8 |
| 8.077e-03 | -4.82 | FEN1 (flap structure-specific endonuclease 1) | protein interactions | 2237 | 76 | 21 | 17029 | 2761 |
RECQL,HARS,PPP1R21,BLM,NCAPG,APP,RAP1A,PCNA,CCNA2,WDR4,MSH2,LRPPRC,LTN1,TNPO3,WDR76,TFG,CDK2,CHPF2,TERF1,MSH6,CDC5L |
| 8.107e-03 | -4.82 | response to organic substance | biological process | GO:0010033 | 2888 | 482 | 17256 | 2622 |
RAB14,MAX,H2AFZ,ADD1,ADAM10,CXXC1,CUL1,CCNB1,PARK7,EEF2K,CDK5,USF1,PSMD1,SRSF4,DNM2,UPRT,TRA2B,TIPARP,DNMT1,CDC5L,BAK1,ERCC1,KLF10,GABPA,AKT2,GNG7,HNRNPF,MCL1,MCM2,SLC25A5,HHEX,SMAD2,WAS,TMED10,RPS27A,PSMD8,PTPN7,OGT,ITGB1,ATP6V0C,RNASEL,SMAD1,ARRB2,LONP2,HDAC2,PFKP,PDCD4,SLC25A33,DDX58,HSPH1,SEC61G,POLR2K,HLA-E,PRKAA1,DHX9,PDCD7,ITGB5,PSEN1,PSMD9,METTL3,CDC73,NPLOC4,LMNA,NDUFS4,CFLAR,TFAP4,FKBP1A,RNF121,PDXP,MEGF8,EFTUD2,DAPK1,ATP6V0A2,CYC1,MYDGF,GNAI2,SOCS5,CYFIP1,ETV3,MAPKAPK3,MAN1B1,ERO1A,MYBL2,USP10,BCLAF1,SRSF5,ADRB2,ARID1A,PKM,ELK1,KDM3A,PSMB3,TWISTNB,FAS,XRCC5,ADSS,DERL1,SEC31A,CAT,EPRS,FNTA,POLR2J,CSK,RBMX,PIAS2,SMPD4,MAP3K5,YY1,CDK2,RNF14,RNF139,KARS,ATXN3,ABCA3,DNMT3A,RWDD1,NQO1,RAB11B,UBR2,RAF1,ACTR3,WDTC1,BCL2L1,PRKACA,CPNE3,APP,GNB2,CRKL,CCNA2,ATP2A2,SHC1,SP100,RALB,MTMR4,ADCY9,SOCS6,CDKN1B,MAVS,TALDO1,CFL1,DCTN1,ADCY7,ATP6V1G1,SHOC2,SEC61B,RFC3,POLR2L,KAT7,WBP2,POLR2D,CUL3,ATP6V0A1,DNAJA1,SHCBP1,PSMB9,SERP1,MAT2A,DDX17,SOCS7,TAF2,ANKZF1,PPP2CA,HSPA4,SEC61A1,DDOST,JAK1,VPS26B,DGCR8,SAFB,HIPK2,SEL1L,STAT1,ATF6,TICAM1,TRIM32,PPP5C,LRP8,DYNC1LI2,CSNK1D,LRCH1,USP13,ADAM23,OTUD5,POU3F2,SRSF6,TWNK,FLOT1,MYNN,AKT1S1,SDF2L1,IP6K2,UBE4A,BLM,ETS1,PMVK,IL21R,FOXO3,HLA-A,TUT4,GTF2F1,CAPN2,PSMD2,PDCD10,PTEN,FUT8,PTPN11,ANXA5,CNN2,CREB1,MAP3K14,UBE2M,NCOA2,HNRNPM,PDPK1,PPP3CA,TNFAIP3,KAT2A,DENND4C,RPL8,LDHA,KCNQ1,PDE3B,POLR2A,FADD,YIF1A,KIF18A,KEAP1,LTBP4,PRDX3,TATDN2,WNT5B,MAPK6,PML,KHSRP,HMGB2,DDX5,ASNA1,PSAP,CD81,YWHAH,IGBP1,CPEB2,FAM83G,SRM,RORB,IER2,AGRN,YTHDC2,ENSA,PTP4A3,SLC29A1,SIRT2,UBQLN2,MAPK14,BECN1,BIRC2,RNF103,MBD4,BCAT2,PRNP,SSR1,ABL2,RAB8A,PCNA,RAP1A,CDC42,EIF4A3,GOT2,RAB35,IL6ST,PIK3R2,TXLNA,AKR1B1,ZFYVE27,OGG1,CARM1,PTPRK,LARS,PTPN18,TRIM8,RBX1,EZR,CDC6,UBE2V1,LRP5,IL12RB1,BRCA1,SOX4,PRKRA,DHX15,MPC1,OPTN,DPYSL3,PAF1,BRWD1,SOCS4,PQBP1,ADAM9,ACTB,CHEK2,CLU,ATP6V0E1,C2CD5,PSMC1,UBE2D3,TMUB1,PHB2,AGTRAP,DNAJB2,CIB1,CDIP1,LAMTOR3,RPL15,TIA1,THRAP3,DNAJB1,PPP3CB,ARID1B,SRRT,RHBDD1,CHKA,RB1,NUS1,MBD2,CAPZA1,CTR9,TIMELESS,BCL2,ATP6V0D1,PREB,ABHD2,TRAFD1,POLR2I,AACS,ERLIN1,ACSL3,GBA,PSMA1,MAP4K3,KRAS,UBE4B,SYVN1,APPL1,DAPK3,ISG15,IRF5,PSMC4,RXRB,TSC1,SYNCRIP,NSMF,KLHL15,NFIL3,LAMTOR4,SLC16A1,PITPNA,NUP62,YWHAZ,RUVBL2,SNRNP70,RBBP4,EHD4,HNRNPDL,ECPAS,TOB1,ADNP2,SMARCD1,TOMM20,GNPNAT1,SLC2A1,SMARCA4,RRAGC,IRF3,ATP6V1B2,DUSP22,LYN,TWF2,HNRNPA2B1,VAV1,PDK2,ATP6V0B,UBXN2A,PSMA6,MDM2,AKAP8,CORO1A,AHCYL1,F2R,PDIA6,CTDSP2,SPIDR,HTRA2,TIMP2,BIRC3,POLR2G,CGAS,PGGT1B,PSMA8,BTG2,SELPLG,CPOX,SLC26A6,PSMB7,ERBIN,HERPUD2,EDEM2,MBD3,TOLLIP,DNAJC10,ATP1A1,IDE,SCAP,TAB2,PSMD3,STAT6,XRCC3,SCARB1,NCOA1,SMURF1,MAPK1,ABCA1,SMAD4,PARD3,MIF,GCLM,CASP6,RAE1,CDT1,AGO2,ARF1,AP3S1,RMI1,DNAJB9,TFRC,PTPN2,KIF5B,HOMER1,FGFR3,IRF4,CTSS,GART,KLHL20,GRK2,TANK,ARHGEF2,STAT3,CAMK2G,MYO5A,RNF5,RNLS,TGFB1,PAQR6,PPP1R9B,RHOA,ADAM17,NASP,PRKDC,PRKAR1B,TUFM,RANGAP1,MEN1,HSPA1B,MAPK3,MFN2,CNOT9,CTSL,HLA-B,CACNB1,TRIM26,ATP6V1D,UPF1,PLAA,BIRC5,TWSG1,ZC3H7B,E2F1,ACAT1,PKD2,SRSF3,PLOD3,ATP6V1C1,NR2F2 |
| 8.118e-03 | -4.81 | central_nervous_system-brain-glioma-oligoastrocytoma_Grade_II | COSMIC cancer mutations | central_nervous_system-brain-glioma-oligoastrocytoma_Grade_II | 34 | 11 | 17385 | 2587 |
GNAS,FGFR3,NRAS,PTEN,VHL,CIC,KRAS,H3F3A,HRAS,CDKN2A,FUBP1 |
| 8.132e-03 | -4.81 | ciliary basal body-plasma membrane docking | biological process | GO:0097711 | 96 | 24 | 17256 | 2622 |
PLK1,FGFR1OP,NPHP4,MAPRE1,DYNLL1,DCTN2,TMEM216,HAUS4,RAB3IP,PRKACA,RAB11A,HAUS2,HAUS8,RAB8A,PCM1,CCP110,CENPJ,ODF2,SSNA1,CEP63,NDE1,TUBB,CSNK1D,DCTN1 |
| 8.137e-03 | -4.81 | BIOCARTA_IL2RB_PATHWAY | MSigDB lists | BIOCARTA_IL2RB_PATHWAY | 38 | 12 | 17377 | 2626 |
CRKL,SHC1,JAK1,RAF1,E2F1,BCL2,BCL2L1,MAPK1,HRAS,MAPK3,FAS,CFLAR |
| 8.137e-03 | -4.81 | GO_NEGATIVE_REGULATION_OF_TYPE_I_INTERFERON_PRODUCTION | MSigDB lists | GO_NEGATIVE_REGULATION_OF_TYPE_I_INTERFERON_PRODUCTION | 38 | 12 | 17377 | 2626 |
DDX58,OTUD5,CYLD,TNFAIP3,RPS27A,PIN1,NLRC5,IRF3,MAVS,RNF135,ISG15,PCBP2 |
| 8.153e-03 | -4.81 | GO_REGULATION_OF_I_KAPPAB_KINASE_NF_KAPPAB_SIGNALING | MSigDB lists | GO_REGULATION_OF_I_KAPPAB_KINASE_NF_KAPPAB_SIGNALING | 226 | 48 | 17377 | 2626 |
MIB2,ASH1L,CYLD,RHOC,IRF3,SLC35B2,UBE2I,SLC20A1,BIRC2,CFLAR,DDRGK1,TERF2IP,FKBP1A,C18orf32,NEK6,ZDHHC13,MAVS,MAP3K14,TFG,F2R,EEF1D,PDPK1,CPNE1,RHOA,BRD4,TRIM8,TNFAIP3,BIRC3,ZMYND11,ATP2C1,MIER1,UBE2V1,FADD,PRDX1,OPTN,RPS27A,TAB2,STAT1,CANT1,NUP62,TICAM1,ZNF268,TRIM32,TMEM101,PPP5C,TRAF5,ZC3HAV1,FAF1 |
| 8.155e-03 | -4.81 | DUF1605 | interpro domains | IPR011709 | 17 | 7 | 18492 | 2768 |
DHX8,DHX16,DHX29,DHX15,DHX57,YTHDC2,DHX9 |
| 8.155e-03 | -4.81 | Thioredoxin_CS | interpro domains | IPR017937 | 17 | 7 | 18492 | 2768 |
TXNL1,DNAJC10,TXN,PDIA6,TMX4,TMX1,TMX3 |
| 8.155e-03 | -4.81 | Plipid/glycerol_acylTrfase | interpro domains | IPR002123 | 17 | 7 | 18492 | 2768 |
AGPAT3,AGPAT2,TAZ,LCLAT1,LPCAT1,LPCAT4,AGPAT1 |
| 8.160e-03 | -4.81 | Insulin receptor recycling | REACTOME pathways | R-HSA-77387 | 27 | 10 | 10287 | 1696 |
ATP6V0B,ATP6V1D,ATP6V0A1,ATP6V0A2,ATP6V0C,ATP6V1B2,ATP6V1C1,ATP6V0E1,ATP6V0D1,ATP6V1G1 |
| 8.216e-03 | -4.80 | NUP62 (nucleoporin 62) | protein interactions | 23636 | 100 | 26 | 17029 | 2761 |
GOPC,RAE1,MOGS,CUL3,NUP54,GORASP2,NUTF2,IKBIP,MCM2,CENPU,OIP5,HSPB11,KPNA1,EIF4A3,PIN1,ACOX1,TXLNA,NUP107,OGT,NUP62,KPNA2,NUP153,SMARCE1,NUP85,NUP58,IFI16 |
| 8.224e-03 | -4.80 | interleukin-12-mediated signaling pathway | biological process | GO:0035722 | 47 | 14 | 17256 | 2622 |
HNRNPA2B1,MIF,JAK1,CDC42,CAPZA1,HNRNPF,PITPNA,CNN2,IL12RB1,ARF1,TALDO1,HNRNPDL,CFL1,PDCD4 |
| 8.224e-03 | -4.80 | cellular response to interleukin-12 | biological process | GO:0071349 | 47 | 14 | 17256 | 2622 |
HNRNPA2B1,MIF,JAK1,CDC42,CAPZA1,HNRNPF,PITPNA,CNN2,IL12RB1,ARF1,TALDO1,HNRNPDL,CFL1,PDCD4 |
| 8.234e-03 | -4.80 | Oncogenic MAPK signaling | REACTOME pathways | R-HSA-6802957 | 75 | 21 | 10287 | 1696 |
AGGF1,NRAS,AGTRAP,NF1,RAF1,TRAK1,BRAP,KRAS,SND1,FXR1,MACF1,MAP2K2,LMNA,MAPK3,RAP1A,CSK,CLCN6,MAPK1,ARRB2,HRAS,ZC3HAV1 |
| 8.234e-03 | -4.80 | Signaling by FGFR2 | REACTOME pathways | R-HSA-5654738 | 75 | 21 | 10287 | 1696 |
POLR2I,NRAS,POLR2G,POLR2L,POLR2K,POLR2D,HNRNPF,TIA1,KRAS,POLR2A,MAPK3,GTF2F1,PPP2CA,MKNK1,SHC1,POLR2J,RPS27A,PTPN11,MAPK1,HRAS,HNRNPM |
| 8.244e-03 | -4.80 | MIT | smart domains | SM00745 | 10 | 5 | 9493 | 1367 |
ULK3,VPS4A,RPS6KC1,SNX15,CAPN7 |
| 8.258e-03 | -4.80 | regulation of neuron death | biological process | GO:1901214 | 281 | 58 | 17256 | 2622 |
GCLM,DNAJC5,NQO1,NF1,MECP2,AKT1S1,BCL2L1,PSEN1,FOXO3,PARK7,PRNP,CDK5,TIGAR,PIN1,KIF14,FBXO7,ZNF746,XRCC2,MSH2,AP2B1,BCL2,CORO1A,TP53BP2,CREB1,ATF2,F2R,STAT3,UBE2M,HTRA2,SRPK2,CHP1,PDPK1,RHOA,SIGMAR1,PPT1,BTG2,OXR1,GBA,MYBL2,MCL1,KRAS,ELK1,PICALM,TSC1,CHMP4A,NSMF,HIPK2,CHMP4B,CLU,ROCK1,CLN3,BTBD10,MAP3K5,PPP5C,ARRB2,HRAS,PSMC1,EGLN1 |
| 8.266e-03 | -4.80 | Kinesin-like_fam | interpro domains | IPR027640 | 43 | 13 | 18492 | 2768 |
KIF5B,KIFC1,KIF2A,KIF3B,KIF18A,KIF18B,KIF14,KIF13B,KIF15,KIF23,KIF22,KIF2C,KIF11 |
| 8.291e-03 | -4.79 | GSE22589_HIV_VS_HIV_AND_SIV_INFECTED_DC_DN | MSigDB lists | GSE22589_HIV_VS_HIV_AND_SIV_INFECTED_DC_DN | 171 | 38 | 17377 | 2626 |
ZBED3,ANKRD27,FEZ2,SYS1,GXYLT1,MUM1,MRPS26,KLF13,RLF,C19orf48,COMMD8,DNAJB9,EBP,KLHL20,BDH1,ADCY9,XPA,TTC4,DNMT1,SPSB3,SNX8,ERMP1,PPP1R18,AATF,ZNF202,PPIE,KIAA0930,MAP7D1,NUP155,MAK16,C1orf131,BRWD1,SNAP23,ZNF367,MEGF9,TAF6,USF2,HRAS |
| 8.291e-03 | -4.79 | GSE2706_UNSTIM_VS_2H_R848_DC_UP | MSigDB lists | GSE2706_UNSTIM_VS_2H_R848_DC_UP | 171 | 38 | 17377 | 2626 |
KIF3B,ZNF786,ANKRD13D,KLHL21,UBR2,ZDHHC8,MUM1,KLF13,SIKE1,EZH1,USP48,SDHA,SPAG5,SLC25A36,PPP1R3B,ZNF302,PPME1,TBC1D14,PHF14,SCYL3,DNAL4,RNF169,SOCS5,NOL8,FRAT2,STYXL1,BBS12,DTWD1,HHEX,ZNF862,PARG,GLG1,VCPIP1,PRMT7,SLC25A19,ACBD4,OSGEPL1,S100PBP |
| 8.291e-03 | -4.79 | GSE21360_PRIMARY_VS_QUATERNARY_MEMORY_CD8_TCELL_UP | MSigDB lists | GSE21360_PRIMARY_VS_QUATERNARY_MEMORY_CD8_TCELL_UP | 171 | 38 | 17377 | 2626 |
DDX58,CYTIP,PTMS,DNMT3A,PLXNC1,NQO1,COX4I1,TFRC,RGS1,LMNA,SRXN1,GNS,TNS3,CLIC4,CCDC50,IL6ST,ZCCHC2,BRI3,ANXA5,GLTP,PACS2,ABCC5,LONRF3,ATP6V0A1,AMDHD2,LY6E,ODC1,CYB5A,MYO1F,DOT1L,PLD3,AHNAK,MTHFD2,STAT1,OGT,PML,LY75,WDR91 |
| 8.291e-03 | -4.79 | GSE6259_33D1_POS_DC_VS_CD4_TCELL_UP | MSigDB lists | GSE6259_33D1_POS_DC_VS_CD4_TCELL_UP | 171 | 38 | 17377 | 2626 |
FGFR1OP,CLSPN,MRPS15,CXXC1,MDH2,RRM1,HMGN3,POMP,NCAPG,ERH,PA2G4,PRKD3,NUP210,IARS,MCM5,RABGAP1L,MSH2,H2AFY,RBM3,MRPL11,SMC4,LARS,GTF3C6,ABHD2,HMGN1,LRBA,KIF15,DNAJC9,ESYT1,CYFIP2,KIF11,MRPS14,POLE,BIRC5,GPS2,LY75,FKBP5,GEN1 |
| 8.314e-03 | -4.79 | KEGG_ENDOMETRIAL_CANCER | MSigDB lists | KEGG_ENDOMETRIAL_CANCER | 52 | 15 | 17377 | 2626 |
PDPK1,NRAS,PTEN,AKT2,AXIN1,RAF1,PIK3R2,AXIN2,KRAS,ELK1,MAPK1,FOXO3,HRAS,MAP2K2,MAPK3 |
| 8.314e-03 | -4.79 | GO_REGULATION_OF_HISTONE_METHYLATION | MSigDB lists | GO_REGULATION_OF_HISTONE_METHYLATION | 52 | 15 | 17377 | 2626 |
PAF1,KDM4A,MECP2,ZNF335,OGT,H2AFY,CTCF,CTR9,RTF1,BRCA1,CHTOP,KDM3A,DNMT1,SMAD4,IWS1 |
| 8.321e-03 | -4.79 | GSE7348_UNSTIM_VS_LPS_STIM_MACROPHAGE_UP | MSigDB lists | GSE7348_UNSTIM_VS_LPS_STIM_MACROPHAGE_UP | 144 | 33 | 17377 | 2626 |
KCTD7,CDT1,UCK1,MEF2A,NHLRC3,RGS2,ASXL2,FOXO3,GIT2,STARD9,ZBTB45,CLUAP1,CD3EAP,TBC1D14,FAM76B,TNRC18,RNF169,SNX8,PLK3,DEAF1,TRIM8,VHL,TLK1,POLG2,ARF4,CCDC127,ITPRIPL1,EIF4ENIF1,MLYCD,NANP,CPEB2,DCAF5,TIGD2 |
| 8.321e-03 | -4.79 | GSE34156_UNTREATED_VS_6H_NOD2_AND_TLR1_TLR2_LIGAND_TREATED_MONOCYTE_DN | MSigDB lists | GSE34156_UNTREATED_VS_6H_NOD2_AND_TLR1_TLR2_LIGAND_TREATED_MONOCYTE_DN | 144 | 33 | 17377 | 2626 |
DDX58,KIF3B,DNMT3A,EWSR1,PARP12,SF3B1,FAM129A,TAP1,MED13L,CTCF,DAZAP2,PSEN1,COMMD8,COPG2,BIRC2,PAPOLA,SP100,CTR9,ARHGEF2,MOB1A,ABI1,TRIM14,PPP1R9B,MAN1B1,OGDH,LY6E,PSMB9,MFN2,NSF,STAT1,CHEK2,SMAD1,EHD4 |
| 8.326e-03 | -4.79 | GO_U12_TYPE_SPLICEOSOMAL_COMPLEX | MSigDB lists | GO_U12_TYPE_SPLICEOSOMAL_COMPLEX | 25 | 9 | 17377 | 2626 |
SNRNP25,SF3B1,SNRPB,YBX1,SNRPG,PDCD7,SNRPD3,DHX15,SF3B2 |
| 8.326e-03 | -4.79 | COLLER_MYC_TARGETS_UP | MSigDB lists | COLLER_MYC_TARGETS_UP | 25 | 9 | 17377 | 2626 |
EIF5A,PPIF,IARS,SLC16A1,AHCY,GPI,FBL,ODC1,TFRC |
| 8.326e-03 | -4.79 | GARGALOVIC_RESPONSE_TO_OXIDIZED_PHOSPHOLIPIDS_MAGENTA_UP | MSigDB lists | GARGALOVIC_RESPONSE_TO_OXIDIZED_PHOSPHOLIPIDS_MAGENTA_UP | 25 | 9 | 17377 | 2626 |
ABL2,C16orf72,PRDM4,KIAA0232,NUP153,RIT1,DNAJA1,KLF6,ZSWIM6 |
| 8.326e-03 | -4.79 | OZEN_MIR125B1_TARGETS | MSigDB lists | OZEN_MIR125B1_TARGETS | 25 | 9 | 17377 | 2626 |
ULK3,LACTB,SEL1L,ATXN1,STAT3,CBFB,QSOX2,LYPLA2,RLIM |
| 8.326e-03 | -4.79 | MODULE_245 | MSigDB lists | MODULE_245 | 25 | 9 | 17377 | 2626 |
FKBP1A,SSR2,TNPO2,KPNA2,ATF6,DNAJA1,PDIA6,SSR1,KDELR1 |
| 8.337e-03 | -4.79 | Jup (junction plakoglobin) | protein interactions | 16480 | 40 | 13 | 17029 | 2761 |
USP7,PPIB,RAB14,TXN,PDCD6,SCAMP3,XAB2,EFTUD2,SMU1,CHMP2B,GAR1,SRRT,CAMK2G |
| 8.337e-03 | -4.79 | DCC (DCC netrin 1 receptor) | protein interactions | 1630 | 40 | 13 | 17029 | 2761 |
EIF2S2,NCK1,SIAH1,RPS10,SIAH2,RPL38,EZR,RPS24,PITPNA,EIF2A,MAPK1,APPL1,MAPK3 |
| 8.337e-03 | -4.79 | NOL3 (nucleolar protein 3) | protein interactions | 8996 | 40 | 13 | 17029 | 2761 |
TERF2IP,VASP,PDCD10,H2AFZ,CSNK2A1,PSMG1,KRAS,EHD4,TERF1,POT1,FADD,CFLAR,FAS |
| 8.337e-03 | -4.79 | ATAD3B (ATPase family, AAA domain containing 3B) | protein interactions | 83858 | 40 | 13 | 17029 | 2761 |
RPN1,EPRS,EIF2S2,SMAD2,SHC1,PHB2,CUL3,USP20,CYC1,USP11,FTSJ3,PPP2R2D,SSR1 |
| 8.337e-03 | -4.79 | PARVA (parvin alpha) | protein interactions | 55742 | 40 | 13 | 17029 | 2761 |
CHMP2A,HSPH1,DDX47,TBC1D17,UGP2,CMTR2,SEC24C,ZRANB2,CCNB1,APP,CARM1,CDC5L,DDX17 |
| 8.337e-03 | -4.79 | DIDO1 (death inducer-obliterator 1) | protein interactions | 11083 | 40 | 13 | 17029 | 2761 |
RPA2,UHRF2,H2AFY,KRAS,JMJD6,RRS1,PCGF1,RBM15,APP,SRSF1,WWP2,SRPK2,RPA1 |
| 8.337e-03 | -4.79 | TMEM237 (transmembrane protein 237) | protein interactions | 65062 | 40 | 13 | 17029 | 2761 |
SRP72,COPA,RAE1,TOR1AIP1,WDR81,LRRC59,MTPN,BCAP31,KTN1,CMTM6,ECH1,COPB2,PRNP |
| 8.340e-03 | -4.79 | Negative feedback regulation of MAPK pathway | REACTOME pathways | R-HSA-5674499 | 6 | 4 | 10287 | 1696 |
MAPK1,MAP2K2,RAF1,MAPK3 |
| 8.346e-03 | -4.79 | GSE30971_CTRL_VS_LPS_STIM_MACROPHAGE_WBP7_KO_2H_DN | MSigDB lists | GSE30971_CTRL_VS_LPS_STIM_MACROPHAGE_WBP7_KO_2H_DN | 182 | 40 | 17377 | 2626 |
RMND5A,PIGM,SUCLG1,NDUFA4,GLUD1,GGA2,ITGB5,SRRT,CHKA,C12orf10,PIN1,PARL,NDUFS8,RNF135,DNMT1,ARL5A,PHKG2,IMPA2,DRAM2,RNF5,TIMM8B,TACC1,PPT1,GALC,DENND1B,DRAP1,MFNG,FBXO9,RHOT1,FOXRED1,HHEX,MKNK1,PON2,SCARB2,MPV17,ZDHHC7,RBPJ,WDR91,LTA4H,RNF114 |
| 8.346e-03 | -4.79 | GSE3982_BCELL_VS_EFF_MEMORY_CD4_TCELL_UP | MSigDB lists | GSE3982_BCELL_VS_EFF_MEMORY_CD4_TCELL_UP | 182 | 40 | 17377 | 2626 |
RAB14,ZBTB10,ST13,NDUFB6,REPS2,TOR3A,ADO,CHD1L,NKRF,RUFY1,MCTS1,IRF4,TNS3,CLIC4,INPP5A,TBC1D22A,SIAH1,DBNDD1,MCM5,TALDO1,MICAL3,TERF2,CCT2,NASP,GNG7,CIRBP,EAF2,USP22,KCNQ1,CLNS1A,TFEB,CAT,SERTAD2,FBXO41,PDLIM1,EIF2D,UQCRH,CHPT1,MRPL13,LTA4H |
| 8.346e-03 | -4.79 | GSE17580_UNINFECTED_VS_S_MANSONI_INF_TREG_DN | MSigDB lists | GSE17580_UNINFECTED_VS_S_MANSONI_INF_TREG_DN | 182 | 40 | 17377 | 2626 |
SEPHS2,SARNP,POLR2K,UQCR10,ZFP91,DAP,UFC1,NENF,POMP,NDUFS4,CDKN2C,LPIN2,ATP13A3,RRBP1,BUD31,RBM3,MINPP1,F2R,LRRC59,DNMT1,TMEM14C,GM2A,S100A6,IMPA2,ACSL5,TIMM8B,RBX1,HTATIP2,NUP155,EPRS,TIMM13,UAP1,ORMDL2,STT3A,DBI,PPM1G,COX8A,BCL7C,FAM126A,MZT2B |
| 8.346e-03 | -4.79 | GSE10239_KLRG1INT_VS_KLRG1HIGH_EFF_CD8_TCELL_DN | MSigDB lists | GSE10239_KLRG1INT_VS_KLRG1HIGH_EFF_CD8_TCELL_DN | 182 | 40 | 17377 | 2626 |
DDX58,PTMS,MAPRE1,PLXNC1,CLSPN,UGP2,DBF4,CTCF,NUF2,NCKAP1,GGPS1,TTF1,UBLCP1,FBXO5,SUB1,SNX18,ZNF260,MOB1A,PLCL2,F2R,NCOA2,CGGBP1,VPS13B,MOB4,ASPM,DENND4C,NUSAP1,RTF1,ANLN,KIF11,KLF6,IDE,RBL1,KBTBD7,WDR7,RBMS1,CNOT6,BTBD10,NGLY1,ESYT2 |
| 8.346e-03 | -4.79 | GSE27786_BCELL_VS_CD4_TCELL_UP | MSigDB lists | GSE27786_BCELL_VS_CD4_TCELL_UP | 182 | 40 | 17377 | 2626 |
GALK1,TRIM41,DYNLL1,TOR1AIP1,USP39,OAT,ATP6V1B2,C19orf48,SAC3D1,ATP6V0B,C1GALT1,TNS3,DUT,CNPY4,MRPL34,BTF3L4,MAVS,LPCAT1,MYO5A,ELOF1,RHOA,USO1,TCTEX1D2,ANKRD37,FAM49B,VHL,PSMB7,SLC16A7,MRPL16,AURKB,CLNS1A,BRWD1,POLR2J,PRDX5,NRM,NCOA1,TRAF5,CD81,RPS26,OAZ1 |
| 8.346e-03 | -4.79 | GSE43700_UNTREATED_VS_IL10_TREATED_PBMC_UP | MSigDB lists | GSE43700_UNTREATED_VS_IL10_TREATED_PBMC_UP | 182 | 40 | 17377 | 2626 |
RMND5A,CYTIP,SMAP1,TRAK1,NOTCH2,RGS2,SLC20A1,SYNRG,RBM17,PHC2,HOMER1,GART,VMP1,DPYSL2,FJX1,BRI3,CITED2,HP1BP3,CCT2,IFRD1,ASPM,VHL,MYBL2,SSR2,ADRB2,AZI2,CBFA2T2,TXNL4A,MAP2K2,RHOB,RPA1,TSC1,SYNCRIP,MRPL55,DHX16,PTER,TFDP1,DTD1,HMGB2,NCOA1 |
| 8.353e-03 | -4.79 | GSE42021_TREG_PLN_VS_CD24INT_TREG_THYMUS_DN | MSigDB lists | GSE42021_TREG_PLN_VS_CD24INT_TREG_THYMUS_DN | 193 | 42 | 17377 | 2626 |
DDX58,UBE2D3,FAM208B,MAX,PARP12,HLA-E,TAP1,UBE2Z,BTN3A1,IRF3,HLA-A,GSTK1,PSMA6,CTSS,CTNNBL1,SP100,PELO,TAP2,STAT3,TRIM14,USO1,TRAFD1,GUK1,LAP3,ERLIN1,SLC25A22,MCL1,OGFR,LY6E,PSMB9,PSMB3,ISG15,FAS,OPTN,HLA-B,NUCB1,PCM1,STAT1,PML,APOL2,IFI16,RNF114 |
| 8.353e-03 | -4.79 | GSE24142_DN2_VS_DN3_THYMOCYTE_DN | MSigDB lists | GSE24142_DN2_VS_DN3_THYMOCYTE_DN | 193 | 42 | 17377 | 2626 |
SLC12A7,TCF12,DNAJC5,TRIM11,CHD1L,MEF2A,AGPAT3,LCLAT1,EXT2,KIAA1147,IRF4,MED10,DAPK1,TPST1,CDKN1B,RNF19A,MINPP1,LDHB,PDPK1,PPT1,TSPYL4,PGS1,BTG2,RFXANK,KDM3A,TOLLIP,CYB5A,AKAP1,PTPRF,CHCHD3,PLD3,MKNK1,HSPB11,GALNT2,PPP2R5A,ETS2,TULP3,SLC16A1,FKBP5,SLAIN1,ZMAT3,TMEM131 |
| 8.353e-03 | -4.79 | GSE19198_1H_VS_6H_IL21_TREATED_TCELL_DN | MSigDB lists | GSE19198_1H_VS_6H_IL21_TREATED_TCELL_DN | 193 | 42 | 17377 | 2626 |
SRM,KARS,TXN,TMEM184B,RAE1,TOR1AIP1,TAP1,HMGN3,ADPGK,KTN1,PNO1,FARSA,CLIC4,TPST1,BRI3,APOOL,STAT3,TIPARP,ATP6V1G1,SAP30,ACSL5,NASP,DDX24,NET1,EMB,PGS1,ASB13,OGFR,LUC7L,PSMB9,HSPA4,MTHFD2,KEAP1,CCDC86,RBL1,BBX,NFIL3,PML,NAA20,BYSL,IPO4,RNF114 |
| 8.353e-03 | -4.79 | GSE3994_WT_VS_PAC1_KO_ACTIVATED_MAST_CELL_DN | MSigDB lists | GSE3994_WT_VS_PAC1_KO_ACTIVATED_MAST_CELL_DN | 193 | 42 | 17377 | 2626 |
TMEM41B,GPR89A,ARID5A,AGPAT3,CLCC1,AP1B1,CSNK1A1,STAM,ABHD16A,ZNF804A,TERF2IP,CLUAP1,ATIC,SEC24C,MDFIC,UBE3B,VPS13B,CPNE1,ENPP4,RPAP3,ARHGAP17,TMEM39A,GALC,EMB,LYRM1,LY6E,KDM1B,ODC1,EVC2,SUGP1,TRAM2,FNTA,NFIL3,EXOC4,ARAP1,RBMS1,MAP3K5,NGLY1,ZMAT3,CSNK1D,GPR89B,ESYT2 |
| 8.353e-03 | -4.79 | GSE21063_CTRL_VS_ANTI_IGM_STIM_BCELL_NFATC1_KO_3H_UP | MSigDB lists | GSE21063_CTRL_VS_ANTI_IGM_STIM_BCELL_NFATC1_KO_3H_UP | 193 | 42 | 17377 | 2626 |
TMED7,CDS2,PARP12,ANXA6,TMEM203,GSPT2,HLA-A,FANCL,ATP6V0B,VMP1,MBD2,ETV6,RAB4A,AP1M1,ANXA5,OSTF1,SPTSSA,S100A6,TMEM160,VOPP1,MND1,PSRC1,TSPYL4,ELL2,TSPAN31,SELPLG,EMB,PSPC1,WBP2,MCFD2,ISG15,RAB18,SMAD2,UAP1,TMED10,UBXN2B,ACLY,APPL2,SEL1L,COX8A,TMEM159,STARD3NL |
| 8.366e-03 | -4.78 | KIAA0753 (KIAA0753) | protein interactions | 9851 | 105 | 27 | 17029 | 2761 |
FGFR1OP,SKA3,LUZP1,CCDC138,FOPNL,GOPC,MAGED1,CAMSAP1,HAUS4,MAP7D1,HAUS2,ECH1,SPAG5,HAUS8,PCM1,CCP110,CCDC14,CENPJ,ODF2,CEP55,GTSE1,CEP63,DVL1,ECD,GCC1,POC5,DVL2 |
| 8.431e-03 | -4.78 | GO_RESPONSE_TO_OXIDATIVE_STRESS | MSigDB lists | GO_RESPONSE_TO_OXIDATIVE_STRESS | 340 | 68 | 17377 | 2626 |
TXN,NQO1,PPP1R15B,SIRT2,APP,PARK7,PRNP,PDK2,MDM2,CCNA2,SHC1,ATP2A2,DNM2,AKR1B1,OGG1,HTRA2,GPX4,PTPRK,PLK3,BAK1,PPIF,ERCC1,PRKRA,ALDH3B1,PON2,STAT6,PRDX5,ARNTL,MPV17,ADAM9,PPP5C,HDAC2,GCLM,PRKAA1,CYCS,PSEN1,ETS1,FOXO3,SRXN1,PDCD10,NDUFB4,XPA,NDUFS8,BCL2,TXNL1,STAU1,TNFAIP3,NET1,OXR1,LDHA,KLF6,MTR,RHOB,PRDX1,HSPA1B,FAS,CAT,KPNA4,PDLIM1,PRDX3,PML,PKD2,MAP3K5,CDK2,CPEB2,ALS2,ADNP2,EGLN1 |
| 8.441e-03 | -4.77 | WDR48 (WD repeat domain 48) | protein interactions | 57599 | 81 | 22 | 17029 | 2761 |
PPIB,PPP1R9B,POLR2I,POLR2G,KDM4A,RAD51AP1,CUL3,CSNK2A1,JMJD6,NFATC2,BRCA1,FANCI,EIF3H,EIF3A,IWS1,PCNA,ZNF639,FBXL7,STK11,TCOF1,DMWD,AHCYL1 |
| 8.441e-03 | -4.77 | STAT5B (signal transducer and activator of transcription 5B) | protein interactions | 6777 | 81 | 22 | 17029 | 2761 |
NCOR2,RPRD1A,ETS1,PDHX,APP,RMC1,ASF1B,CRKL,PTPN2,PPP2CA,SHC1,ETS2,JAK1,CENPJ,STAT1,PTPN11,MVP,TFG,STAT3,MCMBP,MAPK1,RPRD1B |
| 8.473e-03 | -4.77 | positive regulation of protein localization to membrane | biological process | GO:1905477 | 117 | 28 | 17256 | 2622 |
RHOG,PDPK1,TGFB1,AKT2,DYNLL1,ACSL3,ANK3,NKD2,CIB1,EZR,RAB11A,PRNP,MIEF1,KIF5B,CDK5,TFDP1,ITGB1,E2F1,CNPY4,PPP3R1,AP2B1,BCL2,YWHAZ,TP53BP2,TFDP2,YWHAH,C2CD5,CHP1 |
| 8.484e-03 | -4.77 | IRS4 (insulin receptor substrate 4) | protein interactions | 8471 | 110 | 28 | 17029 | 2761 |
COX15,STAU1,NPHP4,PTPN18,RAF1,MAGED1,CUL3,TMEM216,CUL1,AURKB,HAUS2,SOCS7,CRKL,DERL1,MAGED2,HSPA4,PTEN,PIK3R2,ZNF746,PTPN11,SOCS6,YWHAZ,FKBP5,PTGES3,PPP5C,YWHAH,TERF1,TERF2 |
| 8.497e-03 | -4.77 | inner mitochondrial membrane organization | biological process | GO:0007007 | 38 | 12 | 17256 | 2622 |
CHCHD3,IMMT,TIMM13,ATP5MC3,TIMM29,ATP5F1B,ATP5F1A,APOOL,ATP5MF,TAZ,ATP5PF,CHCHD6 |
| 8.506e-03 | -4.77 | MAPK1 (ERK2) activation | REACTOME pathways | R-HSA-112411 | 9 | 5 | 10287 | 1696 |
JAK1,MAPK1,MAP2K2,IL6ST,PTPN11 |
| 8.510e-03 | -4.77 | Canonical Wnt signaling pathway | Pathway Interaction DB | wnt_canonical_pathway | 31 | 12 | 2226 | 426 |
PPP2CA,CSNK1G1,AXIN1,AXIN2,CUL3,NKD2,CUL1,DVL1,CSNK1A1,CSNK1D,DVL2,PI4K2A |
| 8.524e-03 | -4.76 | MRPS22 (mitochondrial ribosomal protein S22) | protein interactions | 56945 | 67 | 19 | 17029 | 2761 |
MRPS2,MRPS15,RPL6,MRPS26,CUL3,CUL1,LUC7L,HAUS2,CAND1,FAM192A,DAP3,GRSF1,QARS,MRPS27,TRMT10B,TARDBP,SNRNP70,SMURF1,ZC3H3 |
| 8.548e-03 | -4.76 | response to unfolded protein | biological process | GO:0006986 | 165 | 37 | 17256 | 2622 |
HSPH1,ADD1,SEC61G,CXXC1,DNAJB2,DNAJB1,RHBDD1,DNAJB9,LMNA,SSR1,RNF121,SHC1,MYDGF,PDIA6,CTDSP2,ATP6V0D1,PREB,DCTN1,BAK1,SEC61B,ERO1A,DNAJA1,SYVN1,HERPUD2,EDEM2,SERP1,HSPA1B,OPTN,MFN2,SEC31A,YIF1A,DERL1,HSPA4,SEC61A1,TATDN2,ATF6,ASNA1 |
| 8.563e-03 | -4.76 | LZTS2 (leucine zipper tumor suppressor 2) | protein interactions | 84445 | 259 | 57 | 17029 | 2761 |
CCNC,PKP4,WDYHV1,SESTD1,EIF3D,RAC1,MYH9,RCOR3,PIP4K2A,FANCL,CCNK,NEK6,CD3EAP,CENPJ,MTA1,AP1M1,GTSE1,CEP63,CPSF4,RBM15,SPATC1L,CNNM3,GCC1,YTHDC1,AMPD2,PPP1R18,ASPM,ELOA,MEMO1,PIP4K2C,CRNKL1,PSMA1,SMC2,CDC23,TXNL4A,CHCHD3,TTLL4,NIP7,DHX16,SPATA2,HIPK2,QARS,ODF2,PITX1,C1orf109,MYO18A,PQBP1,AEN,KPNA2,NDE1,MYO9A,USF2,TRAF5,EYA2,C2CD5,RAD51D,BYSL |
| 8.569e-03 | -4.76 | GO_CELLULAR_RESPONSE_TO_OXYGEN_CONTAINING_COMPOUND | MSigDB lists | GO_CELLULAR_RESPONSE_TO_OXYGEN_CONTAINING_COMPOUND | 767 | 140 | 17377 | 2626 |
RORB,MAX,H2AFZ,AGRN,SIRT2,SLC29A1,CCNB1,MAPK14,PARK7,EEF2K,ABL2,USF1,RAB8A,RAP1A,PIK3R2,DNM2,AKR1B1,DNMT1,PTPRK,CDC5L,KLF10,AKT2,GNG7,EZR,CDC6,BRCA1,SOX4,PAF1,PRDX5,ITGB1,MPV17,OGT,ADAM9,ATP6V0C,CHEK2,ATP6V0E1,HDAC2,SLC25A33,AGTRAP,PRKAA1,LAMTOR3,CDC73,TFAP4,PDXP,ATP6V0A2,CTR9,GNAI2,ATP6V0D1,AACS,OXR1,SRSF5,ELK1,APPL1,MTR,RHOB,FAS,AKAP1,GNAS,CSK,RUVBL2,MAP3K5,CDK2,SMARCD1,ADNP2,DNMT3A,NQO1,RAB11B,RAF1,UBR2,WDTC1,RRAGC,IRF3,BCL2L1,ATP6V1B2,TWF2,LYN,PRKACA,APP,GNB2,ATP6V0B,PDK2,CCNA2,MDM2,SHC1,ADCY9,AHCYL1,HTRA2,ATP6V1G1,ADCY7,PPIF,SLC26A6,ATP6V0A1,SOCS7,IDE,STAT6,TICAM1,SCARB1,PPP5C,MAPK1,ABCA1,LRP8,PAWR,BLM,ETS1,AP3S1,CAPN2,PTPN2,PDCD10,ARHGEF2,ANXA5,CREB1,STAT3,MYO5A,HNRNPM,TGFB1,PDPK1,PPP3CA,TNFAIP3,PRKDC,NET1,DENND4C,PRKAR1B,RANGAP1,KCNQ1,MEN1,KLF6,PDE3B,PRDX1,MAPK3,CBX3,UPF1,ATP6V1D,PRDX3,WNT5B,E2F1,HMGB2,PKD2,ATP6V1C1,CPEB2,BYSL |
| 8.570e-03 | -4.76 | CUI_TCF21_TARGETS_2_UP | MSigDB lists | CUI_TCF21_TARGETS_2_UP | 404 | 79 | 17377 | 2626 |
SRM,SKA3,PTTG1,TPX2,TMEM97,NUF2,TAF6L,STMN1,ABHD14A,ABHD16A,PRNP,PA2G4,CCNA2,ZKSCAN1,PIN1,MRPS27,CDKN1B,KIF22,TACC3,PGAP2,METTL1,RFC3,SNRPB,DNAJC9,ABHD11,CADM1,RPS9,RPSA,PRIM1,CXXC4,TIMM13,RAD18,HNRNPR,DNAJC17,ACTB,CLU,RHEBL1,MIF,GALK1,MRPL9,HJURP,C1orf112,EYA1,CDT1,CDCA8,CDCA3,C19orf25,BLM,BZW2,DTL,ADD3,ATIC,MCM5,BANF1,TIMELESS,KNTC1,ALDH18A1,PPA1,NIPSNAP1,PPAN,TK1,GUK1,RNASEH2C,MAPKAPK3,ASPM,PRKAR1B,UTP15,EVC2,HSPBP1,CDCA7L,CDCA5,PRMT7,NR2F2,ZMIZ1,SNRNP70,UBE2C,CCNB2,ESPL1,SSSCA1 |
| 8.595e-03 | -4.76 | microtubule associated complex | cellular component | GO:0005875 | 147 | 33 | 18223 | 2701 |
STAU1,KIF3B,TCTEX1D2,DYNLL1,DCTN2,KIF15,CDCA8,KIF23,KLC1,HAUS4,TOPORS,KIF2C,AURKB,KIF11,HAUS2,HAUS8,KIF5B,KIFC1,KIF2A,KIF18A,FNTA,KIF18B,BIRC5,KIF14,KIF13B,MAP4,KIFAP3,KIF22,NDE1,LRP8,DNAL4,DYNC1LI2,DCTN1 |
| 8.595e-03 | -4.76 | REACTOME_ENERGY_DEPENDENT_REGULATION_OF_MTOR_BY_LKB1_AMPK | MSigDB lists | REACTOME_ENERGY_DEPENDENT_REGULATION_OF_MTOR_BY_LKB1_AMPK | 17 | 7 | 17377 | 2626 |
CAB39,STK11,TSC1,PRKAB1,TSC2,PRKAA1,RHEB |
| 8.595e-03 | -4.76 | LAMB_CCND1_TARGETS | MSigDB lists | LAMB_CCND1_TARGETS | 17 | 7 | 17377 | 2626 |
TGFB1,KIF22,HSPH1,GNAI2,HEXA,RPS6KA1,AXIN1 |
| 8.595e-03 | -4.76 | GO_ERROR_FREE_TRANSLESION_SYNTHESIS | MSigDB lists | GO_ERROR_FREE_TRANSLESION_SYNTHESIS | 17 | 7 | 17377 | 2626 |
RPA2,PCNA,RFC3,RFC2,RPS27A,NPLOC4,RPA1 |
| 8.595e-03 | -4.76 | GO_DSRNA_FRAGMENTATION | MSigDB lists | GO_DSRNA_FRAGMENTATION | 17 | 7 | 17377 | 2626 |
HNRNPA2B1,SMAD2,PRKRA,SMAD1,DGCR8,METTL3,SRRT |
| 8.595e-03 | -4.76 | GO_PRODUCTION_OF_SMALL_RNA_INVOLVED_IN_GENE_SILENCING_BY_RNA | MSigDB lists | GO_PRODUCTION_OF_SMALL_RNA_INVOLVED_IN_GENE_SILENCING_BY_RNA | 17 | 7 | 17377 | 2626 |
HNRNPA2B1,SMAD2,PRKRA,SMAD1,DGCR8,METTL3,SRRT |
| 8.595e-03 | -4.76 | MODULE_537 | MSigDB lists | MODULE_537 | 17 | 7 | 17377 | 2626 |
BCL2L1,TNFAIP3,BIRC3,BIRC5,BIRC2,CFLAR,MYBL2 |
| 8.614e-03 | -4.75 | FARP1 (FERM, ARH/RhoGEF and pleckstrin domain protein 1) | protein interactions | 10160 | 16 | 7 | 17029 | 2761 |
CAPZA2,BRD2,GAR1,DCAF8,GEMIN7,AKAP1,SDC2 |
| 8.614e-03 | -4.75 | Mki67 (antigen identified by monoclonal antibody Ki 67) | protein interactions | 17345 | 16 | 7 | 17029 | 2761 |
KPNA2,NUP153,NIFK,KPNA4,KPNA1,NOP2,MKI67 |
| 8.614e-03 | -4.75 | WDR90 (WD repeat domain 90) | protein interactions | 197335 | 16 | 7 | 17029 | 2761 |
FGFR1OP,FKBP5,MAPRE1,CCDC14,DYNLL1,TACC3,CUL3 |
| 8.614e-03 | -4.75 | PCNP (PEST proteolytic signal containing nuclear protein) | protein interactions | 57092 | 16 | 7 | 17029 | 2761 |
TERF2IP,XRCC3,USP11,HUWE1,LMNA,CAND1,UHRF2 |
| 8.614e-03 | -4.75 | Klc3 (kinesin light chain 3) | protein interactions | 232943 | 16 | 7 | 17029 | 2761 |
KLC1,KIF5B,C9orf78,FXR1,RAB11A,ZC3H3,ZC3HAV1 |
| 8.614e-03 | -4.75 | MITD1 (microtubule interacting and trafficking domain containing 1) | protein interactions | 129531 | 16 | 7 | 17029 | 2761 |
CHMP2A,CHMP4B,RPRD1A,TFG,MCPH1,CENPU,XRCC5 |
| 8.614e-03 | -4.75 | CCNE2 (cyclin E2) | protein interactions | 9134 | 16 | 7 | 17029 | 2761 |
CDKN1B,PCNA,ORC3,PTEN,CDK2,APP,SUMO2 |
| 8.630e-03 | -4.75 | positive regulation of DNA-templated transcription, elongation | biological process | GO:0032786 | 25 | 9 | 17256 | 2622 |
PAF1,HMGN1,BRD4,THOC1,CTR9,RTF1,CDC73,SUPT16H,GTF2F1 |
| 8.630e-03 | -4.75 | negative regulation of RNA splicing | biological process | GO:0033119 | 25 | 9 | 17256 | 2622 |
HNRNPA2B1,RBM42,RBMX,SRSF6,SRSF4,RNPS1,TRA2B,RPS26,SRSF10 |
| 8.630e-03 | -4.75 | negative regulation of DNA repair | biological process | GO:0045738 | 25 | 9 | 17256 | 2622 |
CYREN,TRIP12,KLHL15,HELB,PARPBP,OGG1,RNF169,TERF2,POLQ |
| 8.635e-03 | -4.75 | MAP1LC3A (microtubule associated protein 1 light chain 3 alpha) | protein interactions | 84557 | 120 | 30 | 17029 | 2761 |
UBQLN4,PDCD6IP,KIF15,SAFB2,MAP1LC3B,TOLLIP,APP,MATR3,OPTN,DDX17,RTKN,EPRS,MDM2,KEAP1,TBC1D17,ASAP2,ATG3,RABGAP1L,SAFB,RRBP1,HADHB,ATG13,DDX5,CLU,NIPSNAP2,DVL2,TUBB,HNRNPM,NIPSNAP1,TMEM160 |
| 8.645e-03 | -4.75 | GSE40274_EOS_VS_FOXP3_AND_EOS_TRANSDUCED_ACTIVATED_CD4_TCELL_UP | MSigDB lists | GSE40274_EOS_VS_FOXP3_AND_EOS_TRANSDUCED_ACTIVATED_CD4_TCELL_UP | 139 | 32 | 17377 | 2626 |
WSB2,ADAM17,ZCCHC8,RAF1,RBM8A,STRN4,ARFIP2,JMJD6,ATG2B,RANGAP1,ADPGK,PLXNA1,MYO9B,AZI2,IKBIP,NDRG3,BZW2,KCMF1,RAD51C,OSBPL11,POLE,CRCP,SLC16A1,MBOAT1,CLDND1,PDXK,RBPJ,MOB1A,CNPY3,NCOA2,SPSB3,NUMB |
| 8.663e-03 | -4.75 | chr7q36 | MSigDB lists | chr7q36 | 57 | 16 | 17377 | 2626 |
ZNF786,TMUB1,KRBA1,CUL1,RHEB,CDK5,ZNF282,ZNF862,ZNF777,XRCC2,ZNF746,LMBR1,PLOD3,UBE3C,CHPF2,ESYT2 |
| 8.663e-03 | -4.75 | CCACACA,MIR-147 | MSigDB lists | CCACACA,MIR-147 | 57 | 16 | 17377 | 2626 |
PDPK1,SHOC2,DNMT3A,GOLPH3L,MECP2,CYP20A1,SNRPA,DHX57,SSR1,ATP1A1,RAD23B,SLC44A1,ACLY,AHCYL1,TIPARP,PURA |
| 8.663e-03 | -4.75 | GO_REGULATION_OF_CELL_CYCLE_G2_M_PHASE_TRANSITION | MSigDB lists | GO_REGULATION_OF_CELL_CYCLE_G2_M_PHASE_TRANSITION | 57 | 16 | 17377 | 2626 |
PLK1,GPR132,BRD4,CLSPN,CENPF,BLM,RAB11A,APP,FANCI,RAD51C,CCNA2,KIF14,H2AFY,GTSE1,ZNF830,CDKN2A |
| 8.663e-03 | -4.75 | SCHEIDEREIT_IKK_INTERACTING_PROTEINS | MSigDB lists | SCHEIDEREIT_IKK_INTERACTING_PROTEINS | 57 | 16 | 17377 | 2626 |
VAV1,HSPA4,CYLD,TRAPPC9,TNFAIP3,RPS6KA1,TANK,E2F1,FKBP5,MAVS,MAP3K14,TFG,ZFAND5,FOXO3,ERC1,CDC37 |
| 8.666e-03 | -4.75 | REACTOME_ERK_MAPK_TARGETS | MSigDB lists | REACTOME_ERK_MAPK_TARGETS | 21 | 8 | 17377 | 2626 |
PPP2CA,MEF2A,ELK1,MAPK14,DUSP3,MAPK1,RPS6KA1,MAPK3 |
| 8.666e-03 | -4.75 | REACTOME_DOUBLE_STRAND_BREAK_REPAIR | MSigDB lists | REACTOME_DOUBLE_STRAND_BREAK_REPAIR | 21 | 8 | 17377 | 2626 |
RPA2,TDP1,BRCA1,XRCC4,PRKDC,RPA1,XRCC5,H2AFX |
| 8.666e-03 | -4.75 | BIOCARTA_MITOCHONDRIA_PATHWAY | MSigDB lists | BIOCARTA_MITOCHONDRIA_PATHWAY | 21 | 8 | 17377 | 2626 |
BAK1,BCL2,CYCS,BCL2L1,BIRC3,CASP6,BIRC2,XIAP |
| 8.666e-03 | -4.75 | GO_NUCLEOTIDE_EXCISION_REPAIR_DNA_INCISION_3_TO_LESION | MSigDB lists | GO_NUCLEOTIDE_EXCISION_REPAIR_DNA_INCISION_3_TO_LESION | 21 | 8 | 17377 | 2626 |
RPA2,ERCC1,RBX1,GTF2H2,CHD1L,DDB1,XPA,RPA1 |
| 8.666e-03 | -4.75 | WU_HBX_TARGETS_2_UP | MSigDB lists | WU_HBX_TARGETS_2_UP | 21 | 8 | 17377 | 2626 |
CSNK1G2,UCK2,PDS5B,HMGB2,BCL2L1,PPP5C,SLC25A5,FAS |
| 8.666e-03 | -4.75 | REACTOME_APC_CDC20_MEDIATED_DEGRADATION_OF_NEK2A | MSigDB lists | REACTOME_APC_CDC20_MEDIATED_DEGRADATION_OF_NEK2A | 21 | 8 | 17377 | 2626 |
CDC16,CDC27,RPS27A,ANAPC7,ANAPC2,CDC23,UBE2C,ANAPC4 |
| 8.666e-03 | -4.75 | REACTOME_REGULATORY_RNA_PATHWAYS | MSigDB lists | REACTOME_REGULATORY_RNA_PATHWAYS | 21 | 8 | 17377 | 2626 |
POLR2I,POLR2J,POLR2G,POLR2L,DGCR8,POLR2K,POLR2A,POLR2D |
| 8.666e-03 | -4.75 | GO_NUCLEOTIDE_EXCISION_REPAIR_PREINCISION_COMPLEX_STABILIZATION | MSigDB lists | GO_NUCLEOTIDE_EXCISION_REPAIR_PREINCISION_COMPLEX_STABILIZATION | 21 | 8 | 17377 | 2626 |
RPA2,ERCC1,RBX1,GTF2H2,CHD1L,DDB1,XPA,RPA1 |
| 8.683e-03 | -4.75 | GO_PERINUCLEAR_REGION_OF_CYTOPLASM | MSigDB lists | GO_PERINUCLEAR_REGION_OF_CYTOPLASM | 611 | 114 | 17377 | 2626 |
RAB14,FGFR1OP,CYLD,TSC2,CHERP,ADAM10,TRIP10,SLC39A13,VTI1A,SIRT2,TWF2,PRKACA,PPP1R16B,LYN,GNB2,APP,BCAP31,CYHR1,RAP1A,ATP2A2,WDR44,RAB4A,DNM2,AKR1B1,ANKRD13C,TP53BP2,MTPN,RHBDD2,CCAR1,MOSPD1,CDC5L,COPS8,UBQLN4,USO1,SEPT9,EZR,DNAJA1,PRKRA,STX16,ODC1,TOLLIP,EIF3G,OPTN,MAP3K4,RAD51C,LIMK1,AXIN1,PRDX5,STAT1,ITGB1,XRCC3,CLU,VPS4A,ABCA1,CSNK1D,PTOV1,NXT2,PPIB,PKP4,ANXA6,CENPF,CIB1,MYO9B,ARF1,RAB11A,SCYL2,TFRC,LMNA,WRNIP1,KIF5B,CAPN2,CLIC4,KLHL20,SEC24C,ARF5,ANP32A,ABCD1,UPF2,MVP,PIKFYVE,S100A6,MOB4,CYFIP1,AGGF1,ACSL3,GTPBP4,RANGAP1,PACS1,PNPLA8,FXR1,ZP3,CYFIP2,EIF4H,MAP2K2,PICALM,HSPA1B,FAS,SEC31A,GNAS,INF2,TPD52L2,TSC1,GALNT2,DBI,LRPPRC,USP20,HMGB2,EHD4,HRAS,NRBP1,DEF6,FAF1,BYSL,SNAPIN |
| 8.687e-03 | -4.75 | CEP162 (centrosomal protein 162) | protein interactions | 22832 | 135 | 33 | 17029 | 2761 |
MAPRE1,LUZP1,MYH9,HAUS4,CCNB1,HAUS2,ANKRD28,RPA2,CEP104,NUP210,CCP110,KIF14,TXLNA,GPATCH1,RPF2,TP53BP2,PLK1,CCDC138,FOPNL,PPP1R21,CAMSAP1,TOP3A,MAP7D1,ANLN,ERC1,HAUS8,RPA1,UPF1,TRIM26,PCM1,CEP55,MYO18A,YWHAH |
| 8.690e-03 | -4.75 | ODF2 (outer dense fiber of sperm tails 2) | protein interactions | 4957 | 130 | 32 | 17029 | 2761 |
FGFR1OP,CYLD,LUZP1,TRAF7,HAUS4,SIRT2,APP,ANKRD28,CRKL,DLG5,RAB8A,CCP110,KIF14,GPATCH1,AP2B1,TP53BP2,DVL2,PLK1,CCDC138,CDC123,CAMSAP1,BRCA1,GIGYF1,HAUS8,EIF4ENIF1,PCM1,SPATA2,CEP55,EXOC4,SMURF1,GEN1,RAB3IL1 |
| 8.699e-03 | -4.74 | regulation of establishment of planar polarity | biological process | GO:0090175 | 112 | 27 | 17256 | 2622 |
RHOA,CELSR2,PSMA8,RAC1,PSMB7,PSMA1,ZNRF3,PSMD9,PSMB9,PSMB3,FZD6,SAPCD2,PSMC4,PSMD2,PSMA6,PSMD1,CDC42,RPS27A,PSMD8,PSMD3,AP2B1,DVL1,SMURF1,ARRB2,AP2S1,PSMC1,DVL2 |
| 8.720e-03 | -4.74 | WH_DNA-bd_sf | interpro domains | IPR036390 | 212 | 45 | 18492 | 2768 |
DEPDC1,FOXM1,ARID2,SHPRH,UBR2,CDT1,CUL1,IRF3,BLM,ETS1,FOXO3,VPS25,GTF2F1,DDRGK1,RPA2,FARSA,PA2G4,IRF4,ETV6,FOXN2,PIKFYVE,DVL2,HP1BP3,MND1,SNRNP200,FOXK1,ETV3,GABPA,ELL2,ERF,CUL3,E2F3,ANAPC2,CDC6,ELK1,IRF5,EIF3K,ETS2,E2F4,PSMD3,TFDP1,E2F1,DVL1,TFDP2,E2F2 |
| 8.725e-03 | -4.74 | Signaling by Hedgehog | REACTOME pathways | R-HSA-5358351 | 138 | 34 | 10287 | 1696 |
CUL1,CSNK1A1,PRKACA,PSMD9,CDC73,PSMD2,PSMD1,PSMA6,GRK2,ADCY9,ADCY7,ULK3,ADAM17,RBX1,PSMA8,PRKAR1B,CUL3,PSMB7,PSMA1,SYVN1,PSMB9,PSMB3,EVC2,PSMC4,GNAS,RPS27A,TULP3,PSMD3,PSMD8,SEL1L,SMURF1,ARRB2,PSMC1,NUMB |
| 8.731e-03 | -4.74 | GSE22443_NAIVE_VS_ACT_AND_IL12_TREATED_CD8_TCELL_DN | MSigDB lists | GSE22443_NAIVE_VS_ACT_AND_IL12_TREATED_CD8_TCELL_DN | 177 | 39 | 17377 | 2626 |
MAPRE1,ST13,MDH2,TRIO,TMEM97,DNAJC24,CHIC2,CHCHD2,XPNPEP3,PRKACA,PSEN1,TMEM161B,KIF5B,RPN1,CLIC4,SLC1A4,ZCCHC2,NAA50,BCAP29,ACAD8,LRRC59,HNRNPM,LYPLA2,RPAP3,CUL3,ATXN1,DDX20,CKAP2L,BICD2,IL12RB1,RAB1A,DDX39A,NUCB1,RBM25,RBL1,U2SURP,OAZ2,NUDT3,ALS2 |
| 8.731e-03 | -4.74 | GSE37563_WT_VS_CTLA4_KO_CD4_TCELL_D4_POST_IMMUNIZATION_DN | MSigDB lists | GSE37563_WT_VS_CTLA4_KO_CD4_TCELL_D4_POST_IMMUNIZATION_DN | 177 | 39 | 17377 | 2626 |
TRERF1,SLC2A1,UCK2,CDCA8,SMARCA4,CHAC2,POMP,BCAP31,MFSD10,SSR1,CREM,DST,LRRC8D,DPYSL2,GTSE1,TECR,SYTL3,LDHB,PLK1,PPAN,HMGN5,PRRC2A,NSDHL,CKAP2L,CCNF,FADD,MAPK3,TMEM184C,WAS,KIF18B,DUSP3,FASTK,NFIL3,CANT1,ATF6,PIEZO1,PGAM1,LRP8,BYSL |
| 8.731e-03 | -4.74 | GSE5099_DAY3_VS_DAY7_MCSF_TREATED_MACROPHAGE_UP | MSigDB lists | GSE5099_DAY3_VS_DAY7_MCSF_TREATED_MACROPHAGE_UP | 177 | 39 | 17377 | 2626 |
CYTIP,HECA,ANXA6,RPLP2,TSC22D3,ANK3,YTHDC2,CIB1,RPL15,S1PR2,CUTC,REEP5,RGS1,EDC3,C14orf119,ADD3,ZNF302,BUD31,PIK3IP1,MRPL11,FAM171A1,TMBIM1,S100A6,ZMYND11,SSR2,MAP7D1,BMS1,DCTD,IL12RB1,PDE3B,NSA2,PFDN5,SGSH,RPL32,QARS,RPS14,NLRC5,IGBP1,S100PBP |
| 8.731e-03 | -4.74 | MCBRYAN_PUBERTAL_BREAST_4_5WK_DN | MSigDB lists | MCBRYAN_PUBERTAL_BREAST_4_5WK_DN | 177 | 39 | 17377 | 2626 |
IMMT,PDCD6IP,SUCLG1,TMEM109,LETMD1,CSNK2A1,UBE4A,ETS1,TFRC,BCAT2,CCNK,APLP2,MLX,PPP1R8,DNM2,AHCYL1,TMEM14C,PPA1,SEH1L,GM2A,CYTH1,AKT2,PFKFB3,ATP6V0A1,UHRF1BP1,LRP5,RAB5B,ZFAND5,ECH1,GALNT2,HIPK2,TPP2,OGT,ACLY,ACAT1,IDH3B,RBBP4,PPP6R3,ACSF2 |
| 8.738e-03 | -4.74 | DNA repair complex | cellular component | GO:1990391 | 39 | 12 | 18223 | 2701 |
PAXX,ERCC1,PRKDC,XPA,RAD23B,PMS2,MSH2,RCOR1,DCLRE1C,XRCC4,MSH6,XRCC5 |
| 8.739e-03 | -4.74 | negative regulation of RNA catabolic process | biological process | GO:1902369 | 52 | 15 | 17256 | 2622 |
SYNCRIP,DHX9,LRPPRC,E2F1,AXIN2,CIRBP,SECISBP2,TARDBP,YBX1,THRAP3,PARN,MAPK14,TOB1,PABPC1,PAIP1 |
| 8.749e-03 | -4.74 | GSE20366_EX_VIVO_VS_HOMEOSTATIC_CONVERSION_TREG_DN | MSigDB lists | GSE20366_EX_VIVO_VS_HOMEOSTATIC_CONVERSION_TREG_DN | 188 | 41 | 17377 | 2626 |
H2AFZ,GADD45G,CENPF,UCK2,CREBL2,STMN1,EEF2K,DTL,CCNA2,KIF22,METTL9,TCTEX1D2,EID1,ASPM,PBK,CPOX,MKI67,RPL38,CCDC34,MAP7D1,CDCA2,NUSAP1,AURKB,SMC2,ERC1,ASF1B,MAPK3,MTHFD2,WAS,NEK1,PDLIM1,HINT1,BIRC5,CERS6,ACAT1,KPNA2,YWHAZ,HMGB2,UBE2C,CCNB2,E2F2 |
| 8.749e-03 | -4.74 | GSE22611_MUTANT_NOD2_TRANSDUCED_VS_CTRL_HEK293T_STIMULATED_WITH_MDP_6H_DN | MSigDB lists | GSE22611_MUTANT_NOD2_TRANSDUCED_VS_CTRL_HEK293T_STIMULATED_WITH_MDP_6H_DN | 188 | 41 | 17377 | 2626 |
GLT8D1,NPHP4,NSMCE4A,GGNBP2,AGRN,PRKCSH,GGA1,TOR3A,CDT1,HABP4,TRAK1,PAWR,ETS1,GLRX3,SDHA,NUP205,CFLAR,MDM2,SLC1A4,MTA1,FBXW2,DDX31,SS18L1,CLTB,CITED2,TMED2,PCBP2,SPSB3,PRPF19,MTA2,NSDHL,JTB,PBRM1,OGFR,SYMPK,UBTF,GOLGA2,CSNK1G1,EIF2D,PPP1R11,IDH3B |
| 8.749e-03 | -4.74 | GSE24726_WT_VS_E2-2_KO_PDC_DAY4_POST_DELETION_DN | MSigDB lists | GSE24726_WT_VS_E2-2_KO_PDC_DAY4_POST_DELETION_DN | 188 | 41 | 17377 | 2626 |
AGTRAP,COPE,TKT,JMJD6,KRI1,SLC31A1,C18orf32,NOL11,MCM5,CS,MRPL54,SEPT11,FBL,MRPL11,TMEM14C,TTPAL,ADAM17,USO1,TNFAIP3,BIRC3,ATG9A,NSDHL,PPP1R21,NSUN2,CRNKL1,USP10,MRPL16,LY6E,PSMB9,PSMB3,SDHB,MTHFD2,TTC13,MAGT1,LSM6,PSMD3,LRPPRC,AEN,GPI,NUDT3,PFKP |
| 8.749e-03 | -4.74 | GSE21670_UNTREATED_VS_TGFB_TREATED_STAT3_KO_CD4_TCELL_DN | MSigDB lists | GSE21670_UNTREATED_VS_TGFB_TREATED_STAT3_KO_CD4_TCELL_DN | 188 | 41 | 17377 | 2626 |
HSPH1,PRPF38B,IMMT,CYLD,GPR132,TRIP10,GNPDA1,RRM1,TBC1D13,BCL2L1,ETS1,GIT2,RGS1,IRF4,RAP1A,JOSD1,BCL2,CYC1,SLC12A2,LRRC59,SYTL3,FGFR1OP2,PHF20L1,CYTH1,TRAFD1,ETV3,CSRP1,ELL2,ATXN1,STK17B,SMAP2,MAN2A2,TPD52L2,SGSH,TXNDC16,HIPK2,CDCA7L,SSNA1,PITRM1,MAPK1,TSPAN5 |
| 8.749e-03 | -4.74 | CAMP_UP.V1_DN | MSigDB lists | CAMP_UP.V1_DN | 188 | 41 | 17377 | 2626 |
UBE2E2,ST13,DYNLL1,TMEM97,OAT,SNN,RGS1,PCYOX1L,DST,DLG5,ASAP2,MBD2,FUT8,SEPT11,TMBIM1,UBE2QL1,DCAF6,TIMP2,BIRC3,MAP4K4,EZR,GLO1,ARHGEF12,NFATC2,ESYT1,DNAJA1,SEPT7,SNRPA,USP36,DPYSL3,UBTF,NAP1L1,ETS2,HINT1,CDCA7L,LMBR1,KLHDC4,ZMIZ1,NUDT11,MAPK1,TSPAN5 |
| 8.749e-03 | -4.74 | GSE21670_STAT3_KO_VS_WT_CD4_TCELL_DN | MSigDB lists | GSE21670_STAT3_KO_VS_WT_CD4_TCELL_DN | 188 | 41 | 17377 | 2626 |
SRM,CYTIP,IMMT,CYLD,GNPDA1,URB2,ARID5A,SLC25A12,BCL2L1,PMF1,IL21R,PNO1,PPP1R3B,IRF4,ITGB8,IARS,ATIC,RPF2,BCL2,POLR1B,ALDH18A1,SLC12A2,PHF20L1,KIAA0040,GTPBP4,LDHA,NARF,SCFD2,MCL1,STK17B,MAT2A,UTP20,TAB2,HIPK2,CDCA7L,TFDP1,RRS1,CDK2,PITRM1,LRP8,BYSL |
| 8.749e-03 | -4.74 | GSE37301_RAG2_KO_VS_RAG2_AND_ETS1_KO_NK_CELL_UP | MSigDB lists | GSE37301_RAG2_KO_VS_RAG2_AND_ETS1_KO_NK_CELL_UP | 188 | 41 | 17377 | 2626 |
UBE2D3,UBL3,IVNS1ABP,GADD45G,PMS2,MAPK14,ETS1,CPNE3,PHC2,PTPN2,GART,INPP5A,TBC1D14,RRBP1,SLC44A1,FOXN2,KIF22,TIPARP,RPAP3,CYTH1,IFRD1,ATP13A1,ERLIN1,LRRC8A,MAP7D1,MAP4K3,PACS1,ESYT1,TOLLIP,SLTM,RPL37,CDC16,CCDC86,VPS26B,ADAM9,DDX5,FKBP5,ABCA1,PDCD4,ANAPC4,ADAM23 |
| 8.749e-03 | -4.74 | GSE10273_LOW_IL7_VS_HIGH_IL7_AND_IRF4_IN_IRF4_8_NULL_PRE_BCELL_DN | MSigDB lists | GSE10273_LOW_IL7_VS_HIGH_IL7_AND_IRF4_IN_IRF4_8_NULL_PRE_BCELL_DN | 188 | 41 | 17377 | 2626 |
WSB2,GGNBP2,GPR132,GXYLT1,UBN1,FLOT1,AGPAT3,NANS,TTF1,LMNA,SPPL2A,C2orf68,VAV1,VASP,TTC9C,FAM89B,DDX31,ATG13,ALDH18A1,ARL5A,NIPAL3,ANKLE2,MOB4,SEPT9,TACC1,PPP1R21,CIRBP,SSR2,ANAPC2,MIER2,COMMD4,GOSR1,MAT2A,NMT2,GALNT2,GPS2,STK38,VCPIP1,RUFY3,EYA2,S100PBP |
| 8.749e-03 | -4.74 | GSE21774_CD56_BRIGHT_VS_DIM_CD62L_POSITIVE_NK_CELL_UP | MSigDB lists | GSE21774_CD56_BRIGHT_VS_DIM_CD62L_POSITIVE_NK_CELL_UP | 188 | 41 | 17377 | 2626 |
CMAS,DNMT3A,PLXNC1,PPP1R12A,FAM76A,NCKAP1,ANKIB1,WRNIP1,SAP130,SLC38A5,WDR44,ADCY9,ZCCHC2,ZDHHC13,TPST1,ANKRD13C,CITED2,ENPP4,SNX25,RDH10,SEPT8,RABIF,RCOR1,FBXO9,GORAB,PTTG1IP,CBFA2T2,NDRG3,SH3GLB1,EPB41,MAGED2,DERL1,MKNK1,OSBPL8,PML,USP32,FAM126A,ZBTB11,ZMAT3,NIPA1,PDCD4 |
| 8.749e-03 | -4.74 | GSE2405_S_AUREUS_VS_A_PHAGOCYTOPHILUM_NEUTROPHIL_DN | MSigDB lists | GSE2405_S_AUREUS_VS_A_PHAGOCYTOPHILUM_NEUTROPHIL_DN | 188 | 41 | 17377 | 2626 |
CCDC93,ANKRD13D,ZNF496,ABCA3,NUP188,KRBA1,DLGAP4,PCSK7,SIKE1,ATG2B,MYO9B,SUPT7L,FBRS,ZER1,HERC3,RINL,INTS1,CLCN6,RPAP1,ANAPC7,CYB5R1,CNNM3,NIPAL3,PBXIP1,ZNF512,MBLAC2,SUGP2,IL12RB1,METTL22,ASB13,RAB5B,ERC1,DHX57,PHF6,ZNF180,DUS3L,CAMKMT,PML,CRCP,ZMAT3,ATMIN |
| 8.749e-03 | -4.74 | GSE18281_PERIMEDULLARY_CORTICAL_REGION_VS_WHOLE_CORTEX_THYMUS_UP | MSigDB lists | GSE18281_PERIMEDULLARY_CORTICAL_REGION_VS_WHOLE_CORTEX_THYMUS_UP | 188 | 41 | 17377 | 2626 |
PRKAB1,TSC2,GNPDA1,KLHL21,TMEM109,TAP1,PSEN1,LRRC14,OIP5,DTL,APLP2,INTS1,SSBP3,MRPS27,KIF22,GEMIN4,CARM1,DCTN1,ZNF500,PBK,BTG2,ANAPC2,NUSAP1,CADM1,MEN1,MCM2,ERC1,ABCF1,POLR2A,IRF5,UPF1,FBXO41,CSK,CEP55,PML,NCOA1,ARRB2,FAM208A,E2F2,PTDSS1,ESPL1 |
| 8.749e-03 | -4.74 | GSE17721_PAM3CSK4_VS_CPG_12H_BMDC_DN | MSigDB lists | GSE17721_PAM3CSK4_VS_CPG_12H_BMDC_DN | 188 | 41 | 17377 | 2626 |
AGRN,RHOC,ARID5A,TBC1D13,CHAC2,GGPS1,WDR48,PTPN2,RCSD1,FUT8,AP2B1,TIPARP,MORC3,SAP30,MOB4,MAPRE2,PPP1R18,CSRP1,ETV3,TMEM39A,SEPT8,MCL1,IL12RB1,DNAJA1,OGFR,RFC2,KLF6,APPL1,RAB22A,SMAP2,ATP6V1D,EIF4ENIF1,KEAP1,CDC27,TAB2,GADD45B,PML,CHMP4B,SASS6,RNF14,IGBP1 |
| 8.749e-03 | -4.74 | GSE17721_LPS_VS_POLYIC_0.5H_BMDC_UP | MSigDB lists | GSE17721_LPS_VS_POLYIC_0.5H_BMDC_UP | 188 | 41 | 17377 | 2626 |
CTDP1,FEZ2,MAX,NUP188,MRPL42,NOP2,ADAM10,HABP4,MOGS,DHX8,LETMD1,BLM,BCAP31,CLUAP1,NEK6,GRSF1,CITED2,LRRC59,KCNAB2,KDELR1,NUDC,MOB4,HARS,GABPA,DENND4C,NSUN2,MRPL12,ARHGDIB,GALK2,ANLN,KRTCAP2,MARK2,ANKRD46,JAK1,GOLGA7,MPV17,AP1S1,DDX5,HEXA,CPEB2,HDAC2 |
| 8.749e-03 | -4.74 | GSE44649_NAIVE_VS_ACTIVATED_CD8_TCELL_UP | MSigDB lists | GSE44649_NAIVE_VS_ACTIVATED_CD8_TCELL_UP | 188 | 41 | 17377 | 2626 |
GNE,LAGE3,SUMF1,LANCL1,MXD4,MAPK14,LYRM2,EXT2,PARK7,TMEM179B,NDUFV1,ANP32A,MRPL40,TALDO1,FYTTD1,CSNK1G2,NTPCR,TK1,SEC61B,SEPT9,POLR2G,RNASEH2C,HTATIP2,ANAPC2,GLO1,IL12RB1,RBM38,PI4K2A,DNAJC10,MRPL2,PDLIM1,HINT1,CCDC6,STK38,CAPN7,OAZ2,WIPI2,TRAF5,IGBP1,NRBP1,MYL12B |
| 8.749e-03 | -4.74 | GSE17721_PAM3CSK4_VS_CPG_0.5H_BMDC_UP | MSigDB lists | GSE17721_PAM3CSK4_VS_CPG_0.5H_BMDC_UP | 188 | 41 | 17377 | 2626 |
MBD1,WASF2,IER2,CHERP,GNPDA1,MECP2,XPO7,OAT,SLC20A1,LRRC14,PHC2,CCNK,FGFR3,DPYSL2,ADCY9,ZNF326,TNPO2,AFF1,MAML1,CNNM3,LYPLA2,GALC,FOPNL,LRBA,RNF25,MAP4K4,KIAA0930,CAMSAP1,UHRF1BP1,SYVN1,HERPUD2,MPG,RPA1,HGS,BRD2,MYO18A,COX8A,CHMP4B,ATP6V1C1,ARHGAP23,TMEM131 |
| 8.749e-03 | -4.74 | peptide transmembrane transporter activity | molecular function | GO:1904680 | 29 | 10 | 17224 | 2647 |
SEC61B,TOMM20,SEC61G,TIMM23,TIMM17A,TAP1,MCL1,TAP2,TOMM40,ABCC1 |
| 8.751e-03 | -4.74 | BAG1 (BCL2 associated athanogene 1) | protein interactions | 573 | 86 | 23 | 17029 | 2761 |
RAF1,RANGAP1,BCL2L1,DNAJB1,SYVN1,EFL1,PARK7,YY1AP1,HSPA1B,KIFC1,RB1,PSMD2,PSMD1,HSPA4,BRD2,SIAH1,ANP32A,LTN1,BCL2,ECPAS,PSMC1,RPRD1B,FUBP1 |
| 8.761e-03 | -4.74 | anchoring junction | cellular component | GO:0070161 | 550 | 102 | 18223 | 2701 |
RHOG,PDCD6IP,ADD1,RPLP2,ADAM10,RAC1,ACTR3,ZFYVE21,MYH9,LYN,CPNE3,GIT2,GNB2,PARK7,DST,DLG5,RAB21,CDC42,SYNM,SH3BP1,DNM2,SENP1,CFL1,PCBP2,CHP1,PTPRK,LAP3,RPL38,EZR,CADM1,STX16,RPS9,ALKBH6,AFDN,AHNAK,JAK1,RPS14,CORO1C,LIMK1,ITGB1,RPLP1,ADAM9,ATP6V0C,ACTB,MAPK1,CAPN1,PARD3,NUMB,PPIB,RPS15,PKP4,RPS2,PPP1R12A,ANXA6,FLOT1,LAMTOR3,CDCA3,B4GALT1,KIF23,SLC4A2,ARF1,NCKAP1,ITGB5,PIP5K1C,CAPN2,CD59,FGFR3,TNS3,VASP,ARPC5,ANXA5,ARHGEF2,RPL19,CNN2,PABPC1,PDPK1,CYFIP1,CYTH1,PPP1R9B,DCAF6,ADAM17,RHOA,FOCAD,CSRP1,RPL6,RPL8,RPS10,KRAS,PLEC,EIF4G2,MAP2K2,RHOB,MAPK3,HSPA1B,CAT,SCARB2,GNA12,PDLIM1,SNAP23,YWHAZ,CD81,PDLIM5 |
| 8.794e-03 | -4.73 | regulation of protein complex assembly | biological process | GO:0043254 | 443 | 86 | 17256 | 2622 |
RHOG,ANKRD27,ADD1,RAF1,CHD1L,RAC1,ACTR3,SIRT2,STMN1,TWF2,BIRC2,PARK7,RRN3,CDC42,RALB,KIF14,CDKN1B,FNIP2,CORO1A,MTPN,SPIDR,CARMIL1,DCTN1,MLST8,ERCC1,PSRC1,RBX1,NCK1,GMFB,VDAC2,WIPF1,PEX5,WAS,IDE,ATXN2L,NCLN,PIEZO1,CLU,H3F3A,SLF1,PSMC1,ABCA1,SVIP,MAPRE1,GMFG,HJURP,MECP2,RHOC,CDT1,ARFIP2,ARF1,NCKAP1,RGS2,JMY,RPA2,SUB1,RB1,VASP,ARPC5,XPA,PTPN11,CAPZA1,ARHGEF2,CREB1,CNOT6L,GTF2H2,PREB,SPTAN1,TGFB1,CYFIP1,RHOA,GBA,CAMSAP1,BCLAF1,CAPZA2,ARPC1A,SH3GLB1,RPA1,CAND1,PSMC4,HSPA1B,CNOT6,TERF1,SLF2,DDB1,FAF1 |
| 8.799e-03 | -4.73 | PRKAB1 (protein kinase AMP-activated non-catalytic subunit beta 1) | protein interactions | 5564 | 49 | 15 | 17029 | 2761 |
SNRNP200,NSF,TRIM11,PRKAA1,MAPK6,CUTA,ACLY,AP1M1,EZR,MCL1,NDUFA7,DCLRE1C,AP1B1,APP,PHKG2 |
| 8.799e-03 | -4.73 | DIABLO (diablo IAP-binding mitochondrial protein) | protein interactions | 56616 | 49 | 15 | 17029 | 2761 |
BIRC3,BIRC5,GABPA,DYNLL1,ZNF746,XIAP,ARL6IP1,AP1B1,DUSP22,TOLLIP,GFER,BIRC2,HTRA2,SSRP1,USP13 |
| 8.799e-03 | -4.73 | PPP1R2 (protein phosphatase 1 regulatory inhibitor subunit 2) | protein interactions | 5504 | 49 | 15 | 17029 | 2761 |
TERF2IP,CDK5,PPP1R9B,EWSR1,POLR2G,KDM2A,TNFAIP8,TUFM,NSFL1C,PPP1R11,CSNK2A1,TP53BP2,TATDN1,GINS4,NCDN |
| 8.799e-03 | -4.73 | CHFR (checkpoint with forkhead and ring finger domains) | protein interactions | 55743 | 49 | 15 | 17029 | 2761 |
CDK5,UBE2D3,PLK1,USP7,UBE2E2,PCNA,BRD4,PBK,PML,SMARCA4,KIF22,MCM2,UBE2I,HDAC2,SMARCD1 |
| 8.799e-03 | -4.73 | ABCA1 (ATP binding cassette subfamily A member 1) | protein interactions | 19 | 49 | 15 | 17029 | 2761 |
SDHB,DLG5,HGS,CDC42,UGP2,LIMK1,GOPC,FLOT1,CSNK2A1,ARHGEF12,FUS,ERBIN,PRKACA,RAPGEF6,FADD |
| 8.799e-03 | -4.73 | CLIC4 (chloride intracellular channel 4) | protein interactions | 25932 | 49 | 15 | 17029 | 2761 |
CRKL,PDCD6,ST13,SHC1,CSK,PSMB7,PSMA1,RABIF,DNAJC9,EZR,YWHAZ,ACTB,TAGLN2,CDK2,DDB1 |
| 8.799e-03 | -4.73 | TIMM44 (translocase of inner mitochondrial membrane 44) | protein interactions | 10469 | 49 | 15 | 17029 | 2761 |
SUGP1,PPIF,PPIB,SARNP,NDUFA2,SEPT9,COQ8A,TIMM17A,ZNF746,RBMS1,ACAT1,CHCHD2,NDUFA4,NDUFA7,APOOL |
| 8.799e-03 | -4.73 | PPIE (peptidylprolyl isomerase E) | protein interactions | 10450 | 49 | 15 | 17029 | 2761 |
EIF4A3,XAB2,BUD31,CRNKL1,YJU2,DHX8,GPATCH1,SNRPG,AQR,ISY1-RAB43,ZNF830,NKAPD1,SF3A2,PRPF19,CDC5L |
| 8.799e-03 | -4.73 | SLC25A4 (solute carrier family 25 member 4) | protein interactions | 291 | 49 | 15 | 17029 | 2761 |
PPIF,COX15,GALNT2,RPS2,ZNF746,TCF3,NDUFA4,VDAC1,CLN3,MCM2,SLC25A5,CDK2,ATP6V0D1,RPSA,GLMP |
| 8.804e-03 | -4.73 | ZHX1 (zinc fingers and homeoboxes 1) | protein interactions | 11244 | 58 | 17 | 17029 | 2761 |
DYNLL1,ZMYND11,SUMO2,NACA,CSNK2A1,ATXN1,BCL2L1,UTP3,UBE2I,TOLLIP,LYAR,CHD3,ZHX1,TARDBP,CREB1,TALDO1,TERF1 |
| 8.804e-03 | -4.73 | BHLHE40 (basic helix-loop-helix family member e40) | protein interactions | 8553 | 58 | 17 | 17029 | 2761 |
COX5B,RHOBTB3,APH1A,TCF3,MAGED1,PRKAA1,UBE2I,TOLLIP,USP21,CCNK,RBM23,CHD3,ZHX1,ARNTL,NAA50,BRD7,STAT3 |
| 8.804e-03 | -4.73 | PIAS3 (protein inhibitor of activated STAT 3) | protein interactions | 10401 | 58 | 17 | 17029 | 2761 |
TRIM8,SUMO2,RAC1,HABP4,UBE2I,CREM,SMAD2,TAB2,SIAH1,SIAH2,GEMIN4,TRIM32,ZMIZ1,STAT3,SMAD4,PSMC1,NCOA2 |
| 8.804e-03 | -4.73 | S100A8 (S100 calcium binding protein A8) | protein interactions | 6279 | 58 | 17 | 17029 | 2761 |
TFAP4,CYLD,SHC1,PTEN,MCM5,DMWD,MCM2,MOB1A,CDK2,USF2,PDCD11,BECN1,POT1,TERF1,APP,TUBB,TERF2 |
| 8.804e-03 | -4.73 | USP28 (ubiquitin specific peptidase 28) | protein interactions | 57646 | 58 | 17 | 17029 | 2761 |
USP7,USO1,CLSPN,FOXK1,ZCCHC8,SUMO2,RFFL,STAM,SPPL2B,USP21,USP5,NSMCE2,UCHL5,USP20,JOSD1,AQR,ESPL1 |
| 8.804e-03 | -4.73 | SAP30 (Sin3A associated protein 30) | protein interactions | 8819 | 58 | 17 | 17029 | 2761 |
NCOR2,FOXK1,PHF23,MTA2,GAR1,MXD1,EBP,BRMS1,SAP130,RBBP4,YY1,SINHCAF,TAF6,TNRC18,ARID4A,HDAC2,DDB1 |
| 8.804e-03 | -4.73 | PIK3C2A (phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha) | protein interactions | 5286 | 58 | 17 | 17029 | 2761 |
PMS2,TKT,MYH9,FAM136A,CAPZA2,ANLN,SEC16A,PICALM,TARS,EIF3A,MAGED2,PA2G4,CDC16,MYO18A,GTSE1,CLTB,ARRB2 |
| 8.804e-03 | -4.73 | BCL2L11 (BCL2 like 11) | protein interactions | 10018 | 58 | 17 | 17029 | 2761 |
ANKLE2,VHL,MTA2,DYNLL1,MCL1,AURKB,BCL2L1,UBQLN2,VDAC1,FOXO3,APP,MAPK3,HSPA4,BCL2,KIF22,MAPK1,ATP6V1G1 |
| 8.804e-03 | -4.73 | CAMKV (CaM kinase like vesicle associated) | protein interactions | 79012 | 58 | 17 | 17029 | 2761 |
BRD4,PNISR,AGRN,AP3M2,SDC2,PIP4K2C,RNPS1,THRAP3,RIT1,APP,UBTF,BRD2,DNAAF2,AFF1,TCOF1,AHCYL1,TNRC18 |
| 8.804e-03 | -4.73 | RNF4 (ring finger protein 4) | protein interactions | 6047 | 58 | 17 | 17029 | 2761 |
UBE2D3,SART1,UBE2E2,MECP2,SUMO2,ATXN1,UBE2I,TRIM28,RPA1,UEVLD,TAB2,PML,TARDBP,NCOA1,USP11,SRPK2,TERF2 |
| 8.832e-03 | -4.73 | clathrin adaptor complex | cellular component | GO:0030131 | 30 | 10 | 18223 | 2701 |
GGA1,AP3M2,AP1M1,AP1S1,AP2B1,AP1B1,GGA2,SYNRG,PICALM,AP2S1 |
| 8.837e-03 | -4.73 | Target Of Rapamycin (TOR) Signaling | WikiPathways | WP1471 | 37 | 12 | 5312 | 837 |
FKBP1A,ULK3,PRKAB1,TSC1,CDC42,TSC2,RAC1,PRKAA1,RRAGC,AKT1S1,RHEB,MLST8 |
| 8.851e-03 | -4.73 | Epithelial cell signaling in Helicobacter pylori infection | KEGG pathways | hsa05120 | 68 | 19 | 7161 | 1149 |
ADAM17,ADAM10,RAC1,ATP6V0A1,ATP6V1B2,LYN,MAPK14,ATP6V0B,ATP6V1D,CDC42,CSK,PTPN11,ATP6V0A2,ATP6V0C,ATP6V1C1,MAP3K14,ATP6V0E1,ATP6V0D1,ATP6V1G1 |
| 8.851e-03 | -4.73 | Epithelial cell signaling in Helicobacter pylori infection | KEGG pathways | ko05120 | 68 | 19 | 7161 | 1149 |
ADAM17,ADAM10,RAC1,ATP6V0A1,ATP6V1B2,LYN,MAPK14,ATP6V0B,ATP6V1D,CDC42,CSK,PTPN11,ATP6V0A2,ATP6V0C,ATP6V1C1,MAP3K14,ATP6V0E1,ATP6V0D1,ATP6V1G1 |
| 8.852e-03 | -4.73 | GO_REGULATION_OF_DNA_BINDING | MSigDB lists | GO_REGULATION_OF_DNA_BINDING | 92 | 23 | 17377 | 2626 |
TGFB1,CPNE1,TXN,HJURP,KAT2A,HABP4,SIRT2,EDF1,PARK7,MAD2L2,DOT1L,CALM2,TFAP4,IRF4,SP100,HIPK2,SRI,E2F1,CEBPG,HMGB2,ZFP90,HDAC2,IFI16 |
| 8.852e-03 | -4.73 | LU_IL4_SIGNALING | MSigDB lists | LU_IL4_SIGNALING | 92 | 23 | 17377 | 2626 |
PHF20L1,RPS2,TNFAIP3,MRPS15,ANKRD33B,KLF13,ATXN1,CMTM6,ATPAF1,CFLAR,GNAS,PPP2CA,NEK6,VMP1,HUWE1,ARPC5,METTL14,NFIL3,APPL2,SIAH2,PPP6C,LY75,MAP3K5 |
| 8.857e-03 | -4.73 | pancreas-carcinoid-endocrine_tumour | COSMIC cancer mutations | pancreas-carcinoid-endocrine_tumour | 7455 | 1165 | 17385 | 2587 |
ZBTB10,TSC2,HEXB,LACTB2,CCNL2,FBXO22,CDKN2C,NAPG,THAP4,RAD23B,MECR,AP1M1,DNM2,UPRT,MGAT5,USP34,CCDC57,RHOBTB3,NRAS,KIF15,WDHD1,MIER2,DIDO1,WBP1,RAB22A,KRIT1,SMAD2,RAD18,PDRG1,MPV17,COX5A,SMAD1,ZNF75A,ANXA11,PDCD4,SLC25A33,ZNF720,HIVEP3,CLSPN,MUM1,TRIO,DHX9,EIF2AK4,APH1B,PARN,CDC73,MYL6B,COPB2,ATG4A,RIMS3,EFTUD2,MVP,NUP85,NSUN4,PPA1,LUC7L2,EIF3L,AGGF1,FOXK1,MTA2,TYW1,SSR2,ITM2A,USP10,MAP7D1,MRPL16,ELK1,SFXN5,FNTA,KPNA1,TXNDC16,PDLIM1,TYW5,WIPI2,TMEM159,PDLIM5,ACSF2,MRPL3,ALS2,FAM72D,TRIM41,POC1A,PTTG1,ANK3,VTI1A,TPX2,INO80E,LCLAT1,GLRX3,KIAA1147,ZNF420,AHCTF1,TBC1D22A,SH3BP1,MTA1,UBA5,NSFL1C,SEPT11,ZC3H3,RPRD1B,ARL5A,SNX8,SEC61B,ERMP1,POLR2L,FAM118B,GOPC,CRNKL1,CIRBP,E2F3,PFKFB3,GORAB,TANC1,RAB1A,GIGYF1,TMEM184C,CORO1C,NSMCE2,CAMKMT,RNF38,SNRPG,PPP5C,USP13,COMMD10,MZT1,ZNF445,ZFP91,HABP4,TRMT6,CCM2,FLOT1,ATG2B,IFT27,SLC25A43,GOLM1,RPA2,ZBTB45,PDCD10,CLIC4,ITGB8,COQ4,CBWD2,ARHGEF1,ANXA5,LTN1,UBE3B,ST8SIA2,STAU1,DDX24,TACC1,LLPH,RAB3IP,TTC33,PICALM,UTP20,SLC19A1,ACOX1,FAM3C,THAP5,WDR13,FAM129A,YTHDC2,SND1,PAPOLA,CREM,FANCL,TET3,RAB8A,NUP210,NT5DC1,SLC44A1,NOC2L,MTPN,ASB6,TACC3,RYBP,VPS13B,PLK1,PTPN18,CELSR2,CDC6,EAF2,LSG1,TRIM4,TRAM2,FBXO28,AGPAT2,ZNF367,ADAM9,KPNA2,BEND6,NGLY1,POT1,MYL12B,NUMB,RMND5A,CENPF,NKD2,SDC2,ADCK5,CDK13,RAB6A,NCKAP1,RSAD1,TNS3,CCP110,MBD2,CTR9,MRPL48,LRSAM1,NTPCR,ABHD2,DCAF8,ACSL3,MAP4K3,METTL22,STYXL1,APPL1,RBM38,NMT2,HAUS8,SDHB,PCM1,GALNT2,NLRC5,SIL1,DTD1,BTBD10,MYO9A,CCNB2,UNC13C,USP7,TRAF7,SUCLG1,ARID2,NDUFAF2,TMX4,TOR1AIP1,TM9SF3,ZFYVE21,LYN,VAV1,OIP5,NRF1,PSMA6,ZNF473,WDR44,PPME1,EFCAB11,TARDBP,AHCYL1,LMAN1,CTDSP2,SNX25,KDM3B,MND1,CLCN3,PPT1,ANKRD33B,PPIE,NUP155,EIF3H,IDE,RBL1,UHRF2,AP1S1,XRCC3,CHMP4B,SMAD4,PARD3,SLC30A9,NADSYN1,CMAS,PDAP1,TMX3,SLC12A9,SCYL2,TUBGCP2,HOMER1,WBP1L,POLR1B,ORC3,RPRD1A,TOP3A,ARHGEF12,ZFR,DDX23,ATP6V1D,SEC23IP,L3MBTL3,E2F1,TAF12,PGAM1,HIPK3,IFI16,NUP188,PDCD6IP,GXYLT1,ADAM10,CXXC1,AP3M2,CUL1,GYG1,NANS,UBE2I,SLC25A37,ANKRD26,NOL11,CISD2,SLC26A2,SRP72,SGCE,OSBP2,KLF10,NSUN2,CLNS1A,EIF3A,IWS1,ZMYM3,TPP2,MAP4,PTPDC1,NMD3,PTOV1,PRPF38B,RECQL,C9orf78,DNAJC5,PRKAA1,C16orf87,ANKH,RRM1,DLGAP4,ACAP1,TATDN3,B4GALT1,PXMP2,FAM136A,PSEN1,PDXDC1,VPS25,NPLOC4,CNOT3,SPAG5,C12orf10,RPN1,CEP104,KLHL5,ZNRF2,MSH2,PIGG,TPST1,FBXL7,OSTF1,FAM171A1,FDFT1,GCC2,PRIM2,ELL2,MFNG,GORASP2,EXOSC9,CAPZA2,ARID1A,FXR1,GOSR1,MAP2K2,CCT8,MTR,TWISTNB,XRCC5,CAT,SLCO4A1,HSPBP1,TTC13,GOLGA2,MED15,USP32,FAM83D,APPL2,CABIN1,SAMD8,SMPD4,GPI,NUDT3,CYTIP,TP53RK,ATXN3,RAB11B,KIAA0232,POMP,BCL2L1,CD320,EPM2A,NUDT19,DECR1,CCNA2,MTMR4,ADCY9,MRPS27,TTC3,RNASEH2A,AQR,CDK12,ANKLE2,CDC123,ELP4,LRRC8A,ERC1,SUPT16H,ZNF282,DDOST,DSN1,DGCR8,SAFB,LMBR1,ATF6,NCLN,EYA2,ADAM23,NDUFS1,B4GALT5,MECP2,MANBA,TKT,CBLL1,SECISBP2,POFUT1,HEATR5B,SLC25A36,WWP2,CCNK,FUT8,PTPN11,BTF3L4,MRPL54,RPL19,CNN2,MTX2,JMJD4,FBXO9,PACS1,KCNQ1,OTUD3,KIF11,MACF1,SMAP2,MYO1F,TMEM127,WDR91,TAF6,DEF6,POLA2,UBL3,LYRM4,GPR132,HMGXB3,PTP4A3,ABCB10,MAP1LC3B,SF3B2,SIVA1,JAZF1,HADHB,RPF2,GPATCH1,SLC35C2,CARM1,WDR41,LARS,ZCCHC10,SNRNP200,CCDC138,VHL,LRBA,SREK1,KMT2C,PRPSAP1,ASF1B,MAN2A2,HSPB11,EIF4ENIF1,U2SURP,MIA2,ZNF268,STK11,CLU,ZSWIM3,CHPT1,MRPL13,TSTD2,DCAF5,ATP6V0E1,CAPN1,UBE2D3,PPP1R12A,ZCCHC8,C19orf25,RGS2,QSOX2,NUP205,PRPF18,LYAR,DTL,MED10,ZRANB1,SLC12A2,ATP6V0D1,TRAFD1,NUDT4,EIF2A,ARHGAP15,EVC2,UAP1,SLC16A1,FN3KRP,YWHAZ,SNRNP70,EHD4,APOL2,ADNP2,FEZ2,MDH2,PMS2,UCK2,SMARCA4,ORC1,MXD1,RRN3,IARS,NVL,EXOSC1,CLTB,POU2AF1,UBQLN4,PGGT1B,PCGF6,SMU1,GLO1,OGDH,CADM1,BICD2,HERPUD2,TOLLIP,MBD3,PDHX,PON2,SURF4,STAT6,ARNTL,FKBP5,TMEM101,CCDC125,MAPK1,ABCA1,PDCD2L,DNAJC2,GCLM,TRIP12,NUP54,VPS45,CHIC2,PAWR,DCUN1D4,GFM2,PIP4K2A,XPR1,FASTKD3,FGFR3,KLHL20,PPIG,RRBP1,H2AFY,LDLRAD3,ERI3,STAT3,SLC35A1,MYO5A,B3GALT6,TXNL1,TMEM39A,PSPC1,HELB,SCFD2,RCOR1,COG1,PRMT2,NDRG3,CDK11A,LEMD2,SERF1B,ELMO1,ZC3H7B,MEGF9,ZMIZ1,PLOD3,HRAS,RAB3IL1,ZSWIM6,CCDC93,RAB14,ADD1,KDM4A,PIGQ,DHX8,PPP1R16B,CDK5,CALM2,NSRP1,RABGAP1L,SRSF4,PDS5B,NUP153,PCBP2,PGAP2,MRPL43,PLEKHM3,PPFIA3,PWWP2B,WDR11,AXIN1,LIMK1,ATE1,FBXL3,E2F2,LONP2,PFKP,DDX42,NDUFV2,CERK,TOP2B,SLC4A2,EZH1,TMED3,ITGB5,LMNA,RAVER2,GNS,DDX56,EIF2S2,INTS7,PHF14,ZNF326,FOXN2,CARS2,UBE2QL1,RB1CC1,DHX29,PGS1,MAN1B1,TEX10,MYBL2,UHRF1BP1,CBFA2T2,ABCF1,PTPRF,SCARB2,OSBPL11,POLR2J,DUSP3,SETD3,CNOT6,NDE1,HEXA,SNX14,EGLN1,PPP1R37,ANKRD27,SARNP,ABCA3,TRERF1,UBR2,ACTR3,WDTC1,MYH9,ZNF267,SAFB2,APP,ANKIB1,STAM,TMEM161B,CLUAP1,PRKD3,ATP2A2,UTP18,GRSF1,ZCCHC2,DDA1,ANKRD13C,ATF2,GCC1,TMEM9,RNF169,ATP6V1G1,ADCY7,SHOC2,MAP4K4,NUSAP1,CDCA2,DDX17,CHCHD3,CDC16,HIPK2,WDR7,MBOAT1,PDXK,LRP8,LRCH1,ZNF786,TMBIM4,SESTD1,TRAK1,GMCL1,JMJD6,AKT1S1,ZNF92,FBXO3,CAPN2,ADD3,NDUFB4,DCP1A,SGCB,IMPA2,NUDC,PPP3CA,POLK,GALC,ZNF512,KIAA0930,ZP3,PDE3B,RPA1,ZNF180,ZNF862,KIF18A,CCDC6,TATDN2,MAPK6,CAPN7,LRPPRC,PML,LY75,RGL1,WDR76,PSAP,USF2,ANAPC4,FAF1,SNAPIN,THOC1,AGRN,GNPDA1,MCCC1,CSNK2A1,SEC16A,GIT2,ATPAF1,LIN9,DLG5,TRMU,ETV6,XRCC2,PPCDC,ZFYVE27,MCMBP,CCAR1,MRPL32,CDC37,ABCC5,METTL1,HARS,GMFB,EZR,LRP5,ANLN,RHEB,OPTN,QRSL1,PIEZO1,GLCCI1,NUDT11,CTCF,RACGAP1,PPP3CB,DOCK11,CRLF3,RB1,VASP,VMP1,SLC27A4,MDFIC,MAML1,TMEM8A,ALDH18A1,TRAPPC9,AACS,MEMO1,UTP15,KRAS,GOLGA4,SYNCRIP,CDC27,PRPS2,TBPL1,PRMT7,KCTD7,UGP2,FOXM1,MRPL39,XAB2,COPE,DUSP22,GGPS1,RAD23A,STRBP,MRPL34,CORO1A,METTL9,MINPP1,DVL2,SLC39A9,CLPTM1,PSMA8,COQ10B,CPOX,SLC26A6,CYP20A1,NFATC2,PRPF3,KDM1B,TXNL4A,RPSA,DNAJC10,ZNF700,SCAP,TIMM17A,CEP55,DNAJC17,NCOA1,USP53,ZC3HC1,INTS2,CTDP1,GOLIM4,MIF4GD,RRP15,DAP,ARID5A,SMC6,SUMF1,GGA2,AP3S1,BZW2,TFRC,WRNIP1,PTPN2,NDUFV1,CWC27,TMA7,ABCD1,DDX31,PTGES3,RPAP3,ZMYM5,PPWD1,RHOT2,CHCHD6,TPD52L2,KPNA4,GOLGA7,TWSG1,SNAP29,CDCA7L,GLG1,PGRMC1,FAM126A,PKD2,RPS6KC1,NDUFB6,TMEM41B,YTHDF3,PLXNA1,NHLRC3,IKBIP,COMMD6,ELMOD2,ABHD14A,KIFC1,ASAP2,SNUPN,CYB5RL,PARPBP,CDC25B,PLCL2,DNMT1,NOL12,AKT2,NOL8,DDX20,GALNT7,SLC17A5,CCNF,SLC25A5,ZFAND5,STT3A,TMED10,PTER,EIF2D,ITGB1,UQCRH,RTN3,ZNF598,DDX58,WSB2,HSPH1,MUT,KIF23,NDUFA4,SLC35B1,PMF1,NOTCH2,NDUFS4,NDUFAF6,FKBP1A,RNF121,HDAC7,BDH1,PIKFYVE,RNF135,LPCAT1,GNAI2,TMED2,MORC3,PIP4K2C,KCTD20,PLEC,ADSS,EPRS,NSF,DCK,ACLY,LPCAT4,VCPIP1,PPP6R2,MAP3K5,YY1,RNF14,CABLES1,ZC3HAV1,DNMT3A,RWDD1,RPS6KA1,SUZ12,SF3B1,URB2,GPR89A,OLA1,SDHA,PHC2,APLP2,ZNF75D,KDM2A,SHC1,UCHL5,TALDO1,NAA35,GPX4,MAPRE2,MKLN1,CUL3,SLBP,KIAA1586,GALK2,CDC23,POLG2,SHCBP1,H2AFV,AP4E1,DHX57,PRDM11,NSA2,VEZF1,HSPA4,JAK1,PPP2R5A,SEL1L,STAT1,KLHDC4,PDCD11,POLQ,PKP4,C1orf112,TCF3,MRI1,SLC25A12,BRAP,AGPAT3,SPR,RAB11A,REEP5,FOXO3,GTF2F1,TMCC3,RBM17,PTEN,CRAT,COPS7B,SLC38A10,UPF2,IFT46,UBE2M,NCOA2,PACS2,ZFP64,DENND1B,NEK7,DENND4C,PARP4,LRRC1,RHOT1,GNA12,FBXO21,NUCB1,C1orf131,HGS,PFDN4,PRDX3,SLC38A7,STX18,TFDP1,KHSRP,BRWD3,BYSL,ESYT2,MIB2,NPHP4,UBE2E2,PLXNC1,ST13,UBN1,DCAF15,DNAJC24,SLC29A1,TAF6L,USP48,MAPK14,EDC3,ZNF804A,THADA,AP3S2,ZNHIT6,IMPAD1,ATG3,DPYSL2,RCSD1,PHTF1,PPP1R12C,AKR1B1,NDUFB9,RP2,NFU1,TTC4,TECR,OGG1,TRIM14,COPS8,FYTTD1,TDP1,TRIM8,FOPNL,SLC16A7,DHX15,GEMIN5,UBTF,CXXC4,ATXN2L,IARS2,GALNT10,PSMC1,SLC12A7,TBC1D12,PIGN,MED13L,TIA1,MEF2A,EPHX2,PITHD1,RHBDD1,ZNF449,CAPZA1,BCL2,KIFAP3,YBX1,GLTP,KNTC1,UBE3C,VOPP1,SEPT7,C22orf46,GNAS,TSC1,RBM25,EXOC4,PITPNA,KIAA1328,PTDSS1,MZT2B,PDSS2,SMARCD1,MMACHC,IMMT,ASH1L,MPHOSPH8,WDYHV1,CHD1,PAIP1,MEAF6,CCDC50,AKAP8,PARL,RPN2,APOOL,F2R,ACSL5,FAM172A,ZNF500,PSMB7,NLN,BTBD1,RAD54B,TAB2,TULP3,WDR59,SCARB1,GAS2,AKNA,SMURF1,TSPAN5,KIF3B,GOLPH3L,MRPL42,CASP6,EYA1,SRGN,KLF13,HDDC2,MAN1A1,CTNNBL1,BRD7,TTC17,GINS1,SAMD4B,ZDHHC18,ADAM17,NASP,ASPM,PRKAR1B,MEN1,ZNF407,SYMPK,SNRPA,MFN2,ATAD2,OSBPL8,PREPL |
| 8.858e-03 | -4.73 | pore complex assembly | biological process | GO:0046931 | 17 | 7 | 17256 | 2622 |
NUP153,NDC1,AHCTF1,CCT8,NUP205,NUP107,TMEM33 |
| 8.858e-03 | -4.73 | positive regulation of intracellular steroid hormone receptor signaling pathway | biological process | GO:0033145 | 17 | 7 | 17256 | 2622 |
UBE2I,PPP5C,RWDD1,PAGR1,PARK7,BUD31,WBP2 |
| 8.858e-03 | -4.73 | magnesium ion transmembrane transport | biological process | GO:1903830 | 17 | 7 | 17256 | 2622 |
NIPAL3,NIPA2,MAGT1,SLC41A1,NIPA1,MRS2,ZDHHC13 |
| 8.858e-03 | -4.73 | regulation of gene expression by genetic imprinting | biological process | GO:0006349 | 17 | 7 | 17256 | 2622 |
PRMT7,KCNQ1,BRCA1,DNMT3A,KDM1B,MECP2,ARID4A |
| 8.858e-03 | -4.73 | centriole replication | biological process | GO:0007099 | 17 | 7 | 17256 | 2622 |
CNTROB,CEP63,CCP110,WDR62,CDK2,SASS6,CENPJ |
| 8.858e-03 | -4.73 | DNA damage response, signal transduction resulting in transcription | biological process | GO:0042772 | 17 | 7 | 17256 | 2622 |
TFAP4,CHEK2,BRCA1,SP100,FOXM1,HIPK2,MAD2L2 |
| 8.858e-03 | -4.73 | Spliceosome, U2-snRNP | KEGG pathways | M00352 | 20 | 8 | 7161 | 1149 |
SNRPG,SNRPD3,SF3B1,SF3A2,SNRPB,SF3B6,DDX42,SF3B2 |
| 8.858e-03 | -4.73 | Spliceosome, U2-snRNP | KEGG pathways | hsa_M00352 | 20 | 8 | 7161 | 1149 |
SNRPG,SNRPD3,SF3B1,SF3A2,SNRPB,SF3B6,DDX42,SF3B2 |
| 8.874e-03 | -4.72 | GO_UBIQUITIN_LIKE_PROTEIN_SPECIFIC_PROTEASE_ACTIVITY | MSigDB lists | GO_UBIQUITIN_LIKE_PROTEIN_SPECIFIC_PROTEASE_ACTIVITY | 118 | 28 | 17377 | 2626 |
OTUD5,USP7,CYLD,ATXN3,TNFAIP3,USP42,FAM76A,USP10,USP39,USP22,OTUD3,USP48,USP21,USP36,USP5,ANKZF1,UCHL5,USP32,VCPIP1,USP20,JOSD1,FAM76B,ZRANB1,USP11,USP53,SENP1,USP34,USP13 |
| 8.874e-03 | -4.72 | GO_INTRINSIC_COMPONENT_OF_ENDOPLASMIC_RETICULUM_MEMBRANE | MSigDB lists | GO_INTRINSIC_COMPONENT_OF_ENDOPLASMIC_RETICULUM_MEMBRANE | 118 | 28 | 17377 | 2626 |
ANKLE2,PIGT,HLA-E,TAP1,SLC35B1,SLC35B2,SYVN1,ESYT1,SPPL2B,BCAP31,RHBDD1,HLA-A,SPPL2A,DERL1,HLA-B,SEC61A1,RRBP1,SLC35B4,PIGG,ARL6IP1,PKD2,ATF6,TAP2,SAMD8,TECR,CLN3,ESYT2,TMEM33 |
| 8.883e-03 | -4.72 | DARWICHE_PAPILLOMA_RISK_LOW_UP | MSigDB lists | DARWICHE_PAPILLOMA_RISK_LOW_UP | 150 | 34 | 17377 | 2626 |
SRM,GALK1,GCLM,COX5B,TXN,H2AFZ,DYNLL1,UCK2,SLC35B1,APP,EXT2,MRPL19,PDXDC1,SPAG5,CHKA,CAPN2,SAR1A,PDS5B,SUCLG2,ATP6V0D1,EEF1D,EIF5A,FTL,TCTEX1D2,LDHA,GBA,LY6E,STX16,SRSF1,IDE,CHPT1,PGAM1,HEXA,UBE2C |
| 8.889e-03 | -4.72 | SEPT6 (septin 6) | protein interactions | 23157 | 36 | 12 | 17029 | 2761 |
SEPT1,TK1,SEPT9,MRPL12,SEPT8,SEPT11,NSD3,TRIM32,SEPT7,ANLN,PLEKHF2,SOCS7 |
| 8.889e-03 | -4.72 | GSTO1 (glutathione S-transferase omega 1) | protein interactions | 9446 | 36 | 12 | 17029 | 2761 |
TXN,PPME1,DUT,UBA5,YTHDC2,LDHA,TAGLN2,ATP5PF,APP,CAPN1,LYPLA2,ECH1 |
| 8.889e-03 | -4.72 | Cct2 (chaperonin containing Tcp1, subunit 2 (beta)) | protein interactions | 12461 | 36 | 12 | 17029 | 2761 |
PDPK1,RAE1,ACTB,ERI3,IGBP1,CCT8,GNB2,SSSCA1,PDCL3,TUBB,MLST8,CSTF1 |
| 8.889e-03 | -4.72 | FERMT3 (fermitin family member 3) | protein interactions | 83706 | 36 | 12 | 17029 | 2761 |
FYTTD1,KEAP1,SNRNP200,PKP4,PDCD6,PRDX5,MRPS27,COX5A,LSM8,KANSL2,APP,PRDX1 |
| 8.889e-03 | -4.72 | RAD9A (RAD9 checkpoint clamp component A) | protein interactions | 5883 | 36 | 12 | 17029 | 2761 |
RPA2,PCNA,CLSPN,TWNK,MSH2,FEM1B,BCL2,BCL2L1,CHEK2,DNMT1,MSH6,RPA1 |
| 8.889e-03 | -4.72 | Ncstn (nicastrin) | protein interactions | 59287 | 36 | 12 | 17029 | 2761 |
DERL1,MRPL2,COPA,SCAMP3,TIMM23,PRKAA1,TRMT6,TATDN3,ATP5MF,PSEN1,ASF1B,MBD4 |
| 8.889e-03 | -4.72 | RAB2B (RAB2B, member RAS oncogene family) | protein interactions | 84932 | 36 | 12 | 17029 | 2761 |
RAB21,RAB14,RAB18,GOLGA2,RAB4A,DMWD,SMAD1,RAB1A,ATF2,RAB5B,APP,SMAD4 |
| 8.889e-03 | -4.72 | SUPT3H (SPT3 homolog, SAGA and STAGA complex component) | protein interactions | 8464 | 36 | 12 | 17029 | 2761 |
SAP130,KAT2A,TCF3,TAF5L,SUPT20H,TAF12,USP22,TAF6L,SUPT7L,SGF29,DDB1,SSSCA1 |
| 8.889e-03 | -4.72 | ARPC5L (actin related protein 2/3 complex subunit 5 like) | protein interactions | 81873 | 36 | 12 | 17029 | 2761 |
ARPC5,TWNK,ACTR3,GADD45G,MYO18A,MYH9,CAPZA2,ANLN,CDK2,ARRB2,ARPC1A,PRKACA |
| 8.899e-03 | -4.72 | COQ9 (coenzyme Q9) | protein interactions | 57017 | 181 | 42 | 17029 | 2761 |
NDUFA5,COX15,NDUFS1,NDUFAF2,TIMM21,CHCHD2,ATP5PF,NDUFS7,GSTK1,COQ4,TIMM23,RAB35,BDH1,NDUFS8,CISD2,MAVS,CYB5R1,SLC25A1,TIMM50,NIPSNAP1,ACSL5,COA3,COQ8A,TIMMDC1,HSDL1,TBRG4,HTATIP2,MTX1,TOMM40,RHOT1,NDUFB1,RHOT2,ECH1,RDH11,STOML2,SDHB,IDE,RAB24,SNAP29,COX5A,SLC16A1,NIPSNAP2 |
| 8.902e-03 | -4.72 | MODULE_493 | MSigDB lists | MODULE_493 | 62 | 17 | 17377 | 2626 |
TRIP10,NSUN2,ZBED5,SEPT8,ZP3,CRLF3,MTR,STARD9,CHD3,PFDN4,CENPT,CHTOP,NDE1,ZMIZ1,SOCS5,ABCC5,ZNF189 |
| 8.902e-03 | -4.72 | REACTOME_RECRUITMENT_OF_MITOTIC_CENTROSOME_PROTEINS_AND_COMPLEXES | MSigDB lists | REACTOME_RECRUITMENT_OF_MITOTIC_CENTROSOME_PROTEINS_AND_COMPLEXES | 62 | 17 | 17377 | 2626 |
PLK1,FGFR1OP,MAPRE1,DYNLL1,DCTN2,TUBGCP5,CCNB1,PRKACA,HAUS2,TUBGCP2,PCM1,CENPJ,SSNA1,CEP63,TUBB,CSNK1D,DCTN1 |
| 8.902e-03 | -4.72 | GNF2_PTPRC | MSigDB lists | GNF2_PTPRC | 62 | 17 | 17377 | 2626 |
CYTH1,CYTIP,HECA,PARP12,HLA-E,TSC22D3,WIPF1,HLA-A,VAV1,HLA-B,WAS,JAK1,STK38,OSTF1,DDX5,CORO1A,ADCY7 |
| 8.912e-03 | -4.72 | internal peptidyl-lysine acetylation | biological process | GO:0018393 | 107 | 26 | 17256 | 2622 |
KAT2A,KAT7,MECP2,LDB1,ELP4,TAF6L,USP22,WDR5,SUPT7L,MBD3,MEAF6,IRF4,MBIP,BRPF3,TEX30,OGT,NAA50,KANSL2,TAF5L,RUVBL2,NCOA1,BEND3,TAF12,ATF2,NAA60,SGF29 |
| 8.920e-03 | -4.72 | GO_RESPONSE_TO_PEPTIDE | MSigDB lists | GO_RESPONSE_TO_PEPTIDE | 393 | 77 | 17377 | 2626 |
MAX,WDTC1,ATP6V1B2,MAPK14,PRKACA,LYN,GNB2,EEF2K,ATP6V0B,PDK2,USF1,RAB8A,MDM2,CCNA2,SHC1,ATP2A2,PIK3R2,ADCY9,AKR1B1,CDKN1B,UPRT,AHCYL1,ATP6V1G1,ADCY7,CDC5L,KLF10,AKT2,BTG2,GNG7,SLC26A6,ATP6V0A1,CDC6,SOCS7,IDE,SCAP,STAT1,OGT,ATP6V0C,LTA4H,MAPK1,ATP6V0E1,SLC25A33,AGTRAP,AP3S1,PTPN2,BDH1,ANXA5,ARHGEF2,ATP6V0A2,CYC1,CREB1,STAT3,ATP6V0D1,MYO5A,PDPK1,TNFAIP3,DENND4C,PRKDC,PRKAR1B,RANGAP1,SRSF5,MEN1,KLF6,PDE3B,APPL1,IRF5,MAPK3,AKAP1,FAS,GNAS,CAT,TSC1,ATP6V1D,CSK,ATP6V1C1,CDK2,CPEB2 |
| 8.927e-03 | -4.72 | Intrinsic Pathway for Apoptosis | REACTOME pathways | R-HSA-109606 | 44 | 14 | 10287 | 1696 |
BAK1,AKT2,DYNLL1,TFDP1,XIAP,E2F1,PPP3R1,CYCS,YWHAZ,BCL2,BCL2L1,TP53BP2,TFDP2,YWHAH |
| 8.935e-03 | -4.72 | PHD | pfam domains | PF00628 | 53 | 15 | 17054 | 2545 |
PHF10,CHD3,BAZ2A,KMT2E,PHF23,PHRF1,CXXC1,PHF14,UHRF2,KMT2B,BAZ1B,INTS12,DIDO1,KMT2C,TRIM28 |
| 8.944e-03 | -4.72 | GO_INTRINSIC_COMPONENT_OF_MITOCHONDRIAL_MEMBRANE | MSigDB lists | GO_INTRINSIC_COMPONENT_OF_MITOCHONDRIAL_MEMBRANE | 43 | 13 | 17377 | 2626 |
BAK1,CHCHD3,IMMT,TOMM20,TIMM23,TIMM17A,ABCB10,APOOL,TOMM40,RHOT1,RHOT2,CHCHD6,MFN2 |
| 8.944e-03 | -4.72 | BRACHAT_RESPONSE_TO_CAMPTOTHECIN_DN | MSigDB lists | BRACHAT_RESPONSE_TO_CAMPTOTHECIN_DN | 43 | 13 | 17377 | 2626 |
BAK1,CORO7,OSTF1,ANP32E,BCL2,GPI,ESYT1,BTF3,SLC25A5,STMN1,FKBP3,TUBB,SLC25A1 |
| 8.944e-03 | -4.72 | NUTT_GBM_VS_AO_GLIOMA_DN | MSigDB lists | NUTT_GBM_VS_AO_GLIOMA_DN | 43 | 13 | 17377 | 2626 |
YIF1A,PPIF,RPLP2,ELMO1,VDAC2,CIRBP,TMEM97,CRY2,ZMIZ1,RPL27A,API5,PDHX,RPL23A |
| 8.944e-03 | -4.72 | KEGG_PROTEASOME | MSigDB lists | KEGG_PROTEASOME | 43 | 13 | 17377 | 2626 |
PSMD2,PSMD1,PSMA6,PSMA8,PSMD8,PSMD3,PSMB7,PSMA1,POMP,PSMB9,PSMC1,PSMB3,PSMC4 |
| 8.944e-03 | -4.72 | GO_DNA_METHYLATION | MSigDB lists | GO_DNA_METHYLATION | 43 | 13 | 17377 | 2626 |
GNAS,TET3,DNMT3A,HEMK1,BAZ2A,MTA2,EHMT1,PRMT7,CTCF,BEND3,KDM1B,DNMT1,TRIM28 |
| 8.944e-03 | -4.72 | GO_DNA_ALKYLATION | MSigDB lists | GO_DNA_ALKYLATION | 43 | 13 | 17377 | 2626 |
TET3,GNAS,HEMK1,DNMT3A,BAZ2A,MTA2,EHMT1,CTCF,PRMT7,BEND3,KDM1B,DNMT1,TRIM28 |
| 8.957e-03 | -4.72 | nucleotide-excision repair, DNA incision, 3'-to lesion | biological process | GO:0006295 | 21 | 8 | 17256 | 2622 |
RPA2,ERCC1,RBX1,XPA,CHD1L,GTF2H2,DDB1,RPA1 |
| 8.957e-03 | -4.72 | genetic imprinting | biological process | GO:0071514 | 21 | 8 | 17256 | 2622 |
GNAS,PRMT7,KCNQ1,BRCA1,DNMT3A,KDM1B,MECP2,ARID4A |
| 8.957e-03 | -4.72 | protein targeting to lysosome | biological process | GO:0006622 | 21 | 8 | 17256 | 2622 |
NAGPA,GCC2,SCARB2,LARS,CLU,HGS,VPS4A,RAB7A |
| 8.957e-03 | -4.72 | nucleotide-excision repair, preincision complex stabilization | biological process | GO:0006293 | 21 | 8 | 17256 | 2622 |
RPA2,ERCC1,RBX1,XPA,CHD1L,GTF2H2,DDB1,RPA1 |
| 8.973e-03 | -4.71 | GO_CELLULAR_RESPONSE_TO_RADIATION | MSigDB lists | GO_CELLULAR_RESPONSE_TO_RADIATION | 134 | 31 | 17377 | 2626 |
BAK1,NET1,PBK,RAD51AP1,TMEM109,AURKB,BCL2L1,EIF2AK4,BLM,ELK1,MAPK14,RHBDD1,RHOB,XRCC5,RDH11,MDM2,PCNA,INTS7,XPA,H2AFX,ITGB1,DNM2,NOC2L,CRY2,STK11,RUVBL2,YY1,EEF1D,IFI16,DDB1,PTPRK |
| 9.001e-03 | -4.71 | human chr18q22.3 | chromosome location | human chr18q22.3 | 18 | 6 | 26185 | 2809 |
TIMM21,TSHZ1,CBLN2,ZNF407,ZADH2,CYB5A |
| 9.022e-03 | -4.71 | BAIAP2 (BAI1 associated protein 2) | protein interactions | 10458 | 72 | 20 | 17029 | 2761 |
WASF2,CYFIP1,BRD4,RHOA,RAC1,C19orf25,RAB3IP,NCKAP1,CYFIP2,MARK2,APP,DECR1,ZBTB21,PCM1,CDC42,KIF13B,PPIL2,TP53BP2,ABI1,SRPK2 |
| 9.022e-03 | -4.71 | Dctn3 (dynactin 3) | protein interactions | 53598 | 72 | 20 | 17029 | 2761 |
GCC2,MLEC,TCF3,DCTN2,CAPZA2,GAR1,RPSA,PRDX1,DAPK3,GTF2F1,SEC61A1,SNAP29,MYO18A,CAPZA1,HMGB2,TAF6,DNMT1,AP2S1,STRAP,DCTN1 |
| 9.032e-03 | -4.71 | V$USF_02 | MSigDB lists | V$USF_02 | 261 | 54 | 17377 | 2626 |
TCF12,RPS2,MAX,DNMT3A,PPCS,ATXN3,UROD,SUMF1,TAF6L,RLF,COMMD8,GNB2,FZD6,SSR1,CSDE1,FAM192A,TFAP4,CDKN2C,SMC3,COQ4,PRDM4,H2AFY,PABPC1,DVL2,CCAR1,NUDC,SNX8,PHF20L1,LONRF3,AATF,C16orf72,SIGMAR1,TOP3A,ILF3,LRP5,TOPORS,UBE4B,NDUFA7,PICALM,EIF3A,MAT2A,RHBDF2,EPB41,EIF3K,SEC23IP,HPS5,LUC7L3,MRPL27,ASNA1,MBD6,ATP6V1C1,CLN3,RAB3IL1,RHEBL1 |
| 9.045e-03 | -4.71 | DUSP | prosite domains | PS51283 | 7 | 4 | 12060 | 1670 |
USP20,USP11,USP48,USP32 |
| 9.045e-03 | -4.71 | RECA_2 | prosite domains | PS50162 | 7 | 4 | 12060 | 1670 |
RAD51C,XRCC3,RAD51D,XRCC2 |
| 9.045e-03 | -4.71 | U_BOX | prosite domains | PS51698 | 7 | 4 | 12060 | 1670 |
UBE4B,UBE4A,PPIL2,PRPF19 |
| 9.049e-03 | -4.71 | RAGHAVACHARI_PLATELET_SPECIFIC_GENES | MSigDB lists | RAGHAVACHARI_PLATELET_SPECIFIC_GENES | 67 | 18 | 17377 | 2626 |
MAX,WIPF1,ASAH1,EIF2AK1,SNN,RUFY1,ODC1,ITGB5,PIP4K2A,APP,GNAS,KIF2A,NAP1L1,PDLIM1,RABGAP1L,PGRMC1,CTSA,RYBP |
| 9.049e-03 | -4.71 | GO_CELL_AGING | MSigDB lists | GO_CELL_AGING | 67 | 18 | 17377 | 2626 |
MIF,ULK3,ERCC1,SMC6,MAPK14,NSMCE2,ARNTL,H2AFX,PML,NUP62,BCL2,CHEK2,ZMIZ1,HRAS,CDKN2A,PDCD4,TERF2,MORC3 |
| 9.052e-03 | -4.70 | GO_OXIDATION_REDUCTION_PROCESS | MSigDB lists | GO_OXIDATION_REDUCTION_PROCESS | 841 | 152 | 17377 | 2626 |
COX15,TXN,NDUFB6,KDM4A,UQCR10,ALKBH5,DNAJC24,GLUD1,GYG1,MAPK14,PARK7,PCYOX1L,ASPHD2,CALM2,TET3,CYB5RL,IL6ST,MECR,HADHB,AKR1B1,SUCLG2,NDUFB9,TECR,KCNAB2,AKT2,HSDL1,RRM2,FOXRED1,UEVLD,RPS27A,PRDX5,DHTKD1,COX5A,UQCRH,PFKP,COX5B,NDUFV2,PPP1R2,PRKAA1,ADO,RRM1,NDUFA4,COX4I1,CYCS,QSOX2,RSAD1,NDUFS7,NDUFS4,BDH1,CYC1,ACAD8,ALDH18A1,PHKG2,ALDH9A1,FDFT1,TSTA3,CREG1,NSDHL,NQO2,OXR1,TYW1,RDH10,VKORC1,KDM3A,CYB5A,RDH11,CAT,GNAS,SDHB,MTHFD2,COX7A2L,TYW5,MDH1,GPI,EGLN1,NDUFA5,MMACHC,SUCLG1,UGP2,NQO1,NDUFAF2,MDH2,TMX4,ZADH2,GLRX3,SDHA,EPM2A,NUDT19,DECR1,DUS4L,KDM2A,CS,CYB5R1,GPD1L,GPX4,KDM3B,HPDL,IDH3A,CPOX,CYP20A1,HTATIP2,PFKFB3,OGDH,NDUFA7,KDM1B,NDUFB1,POLG2,TAZ,GFER,ALKBH6,ALDH3B1,DNAJC10,DUS3L,NDUFA11,NDUFS1,MECP2,TMX3,SLC25A12,SUMF1,JMJD6,SPR,SRXN1,PPP1R3B,FASTKD3,GSTK1,NDUFV1,NDUFA2,NDUFB4,CRAT,ABCD1,NDUFS8,NDUFA3,TMX1,RNLS,MICAL3,LDHB,TXNL1,LDHA,TBRG4,ECH1,PRDX1,PRDX3,ACOX1,COX8A,IMPDH1,ACADM,NDUFS5,IDH3B,PLOD3,PGAM1,HIGD2A,TYW1B |
| 9.070e-03 | -4.70 | GO_TRANSITION_METAL_ION_BINDING | MSigDB lists | GO_TRANSITION_METAL_ION_BINDING | 1314 | 229 | 17377 | 2626 |
MIB2,RORB,PTMS,KDM4A,ADAM10,ZDHHC8,PHRF1,CXXC1,TRIM11,XIAP,DNAJC24,USP39,SIRT2,CDIPT,RUFY1,CUTC,POLR3K,KCMF1,BIRC2,PARK7,TRIM65,RBM4,RNF103,PAPOLA,PRNP,ABL2,SIVA1,MECR,NUP153,NFU1,TCEA1,MARCH2,RNF26,ZNRD1,DNMT1,TRIM14,RYBP,TRIM8,BAZ2A,LAP3,RBX1,EHMT1,LNX2,TOPORS,BRCA1,USP22,DIDO1,ZFAND5,ZMYM3,CXXC4,MAN2A2,TRIM4,TRIM47,TIMM13,RAD18,CHD3,PTER,LIMK1,BAZ1B,ADAM9,TRIM52,ZSWIM3,TRAF5,ZNF598,ZMAT3,DDX58,EWSR1,ZCCHC9,PHF23,ZCCHC8,POLR2K,CUTA,CTCF,B4GALT1,MAN2B1,ZNRF3,XPNPEP3,RLF,NPLOC4,RNF121,LHX8,MEX3C,ZNRF2,RNFT1,PHF14,PIKFYVE,RNF135,ZRANB1,CPSF4,LRSAM1,MORC3,PHF10,FTL,TIMM8B,POLR2I,ZNF84,ZMYND11,MTA2,TYW1,DCTD,SYVN1,KDM3A,SF3A2,ZDHHC3,MATR3,MTR,PHF6,RXRB,GALNT2,PDLIM1,TYW5,SIAH2,PIAS2,ZDHHC7,YY1,ZNF830,RNF14,PDLIM5,RNF139,RNF114,EGLN1,MBD1,ZNF207,TRIM41,ASH1L,CYLD,TRAF7,UBR2,UROD,ZADH2,TCF19,ANKIB1,APP,USP5,PHC2,APLP2,CYHR1,ZNF75D,MDM2,KDM2A,BRPF3,SIAH1,MTA1,AKAP8,ZCCHC2,INTS12,TTC3,RNF19A,RNF169,RLIM,POLR2L,BIRC3,PGGT1B,KAT7,RNF25,CYP20A1,PCGF6,GLO1,KDM1B,TRIM28,TAF2,AMZ2,ZNF282,IDE,TAB2,NSMCE2,RNF38,UHRF2,TRIM32,PDXK,LTA4H,PITRM1,ZNF146,ZC3HC1,USP13,ADAM23,PDF,SHPRH,DBF4,BRAP,CBLL1,MYNN,JMJD6,LANCL1,MYO9B,ZNF92,NEIL2,RFWD3,SUV39H2,SEC24C,PRDM4,ZDHHC13,LTN1,ARHGEF2,FBXL19,GTF2H2,S100A6,RNF5,MICAL3,PDLIM2,ZDHHC18,ADAM17,TK1,TNFAIP3,CSRP1,LONRF3,ZMYM5,ATP2C1,TOP3A,RABIF,RFFL,PCGF1,ZNF407,ZFR,TRIM26,UPF1,POLE,BIRC5,ZNF330,NEIL3,PML,DTX4,USP20,ZRANB2,NR2F2,ZMIZ1,PLOD3,TYW1B,ZSWIM6 |
| 9.073e-03 | -4.70 | FoxO signaling pathway | KEGG pathways | hsa04068 | 132 | 32 | 7161 | 1149 |
PDPK1,PLK3,TGFB1,USP7,PLK1,PRKAB1,NRAS,AKT2,RAF1,PRKAA1,GADD45G,KRAS,CCNB1,MAPK14,FOXO3,MAP2K2,MAPK3,CAT,HOMER1,MDM2,SMAD2,PTEN,GADD45B,PIK3R2,CDKN1B,STK11,CDK2,CCNB2,MAPK1,STAT3,HRAS,SMAD4 |
| 9.074e-03 | -4.70 | GO_HYDROGEN_ION_TRANSMEMBRANE_TRANSPORT | MSigDB lists | GO_HYDROGEN_ION_TRANSMEMBRANE_TRANSPORT | 82 | 21 | 17377 | 2626 |
COX5B,COX15,UQCR10,ATP6V0A1,NDUFA4,COX4I1,ATP6V1B2,CYB5A,STOML2,ATP6V0B,ATP1A1,COX7A2L,COX8A,ATP6V0A2,COX5A,UQCRH,ATP6V0C,ATP6V1C1,ATP6V0E1,ATP6V0D1,ATP6V1G1 |
| 9.077e-03 | -4.70 | lentigo_maligna | COSMIC cancer mutations | lentigo_maligna | 30 | 10 | 17385 | 2587 |
FGFR3,NRAS,PTEN,SF3B1,RAC1,STK11,KRAS,MEN1,HRAS,CDKN2A |
| 9.081e-03 | -4.70 | signal sequence binding | molecular function | GO:0005048 | 47 | 14 | 17224 | 2647 |
TOMM20,PEX5,KPNA4,BABAM2,KPNA1,TNPO3,AP2B1,BRAP,TNPO2,NUP153,KPNA2,NUP58,IPO4,KDELR1 |
| 9.082e-03 | -4.70 | MORF_ATRX | MSigDB lists | MORF_ATRX | 205 | 44 | 17377 | 2626 |
TCF12,ST13,POLR2K,UBR2,SLC2A1,KLHL18,CDK13,NKRF,PARN,FAM8A1,PDXDC1,RB1,RAP1A,KLHL20,TBC1D22A,PPIL2,GTSE1,ATP6V0A2,LTN1,BCL2,ZBTB22,TAF5L,GLE1,CPSF4,MICAL3,CAMK2G,KDM3B,PHF10,ZNF500,UBE4B,BRCA1,MTX1,PCGF1,ERC1,TAF2,SEC31A,LTBP4,CHD3,PIAS2,WDR62,PPP5C,RNF14,IGBP1,NUMB |
| 9.108e-03 | -4.70 | ER-Phagosome pathway | REACTOME pathways | R-HSA-1236974 | 85 | 23 | 10287 | 1696 |
SEC61B,PSMA8,SEC61G,HLA-E,TAP1,PSMB7,PSMA1,PSMB9,PSMD9,PSMB3,HLA-A,PSMC4,HLA-B,PSMD2,PSMA6,PSMD1,SEC61A1,RPS27A,PSMD8,SNAP23,PSMD3,TAP2,PSMC1 |
| 9.111e-03 | -4.70 | JIANG_AGING_CEREBRAL_CORTEX_UP | MSigDB lists | JIANG_AGING_CEREBRAL_CORTEX_UP | 34 | 11 | 17377 | 2626 |
CASP6,DCK,GADD45B,TRA2B,RPS24,BCAP29,ACTB,PABPC1,FKBP3,PRDX1,CDC5L |
| 9.111e-03 | -4.70 | ST_WNT_BETA_CATENIN_PATHWAY | MSigDB lists | ST_WNT_BETA_CATENIN_PATHWAY | 34 | 11 | 17377 | 2626 |
CXXC4,AKT2,AXIN1,PIN1,AXIN2,NKD2,DVL1,MVP,PSEN1,CSNK1A1,RPSA |
| 9.111e-03 | -4.70 | GO_TRANSCRIPTION_FROM_RNA_POLYMERASE_I_PROMOTER | MSigDB lists | GO_TRANSCRIPTION_FROM_RNA_POLYMERASE_I_PROMOTER | 34 | 11 | 17377 | 2626 |
UBTF,RRN3,POLR2L,POLR2K,CD3EAP,POLR1B,ZNRD1,GTF2H2,TTF1,TWISTNB,MAPK3 |
| 9.111e-03 | -4.70 | BIOCARTA_MPR_PATHWAY | MSigDB lists | BIOCARTA_MPR_PATHWAY | 34 | 11 | 17377 | 2626 |
GNAS,ARPC5,PIN1,RPS6KA1,ACTR3,PRKAR1B,CCNB1,MAPK1,ARPC1A,HRAS,MAPK3 |
| 9.111e-03 | -4.70 | HU_GENOTOXIN_ACTION_DIRECT_VS_INDIRECT_4HR | MSigDB lists | HU_GENOTOXIN_ACTION_DIRECT_VS_INDIRECT_4HR | 34 | 11 | 17377 | 2626 |
ARF5,PPIE,ATP6V0A2,MCL1,ACTB,KRAS,PITPNB,ICAM2,IFT46,DVL2,SMC4 |
| 9.114e-03 | -4.70 | Cyclin A:Cdk2-associated events at S phase entry | REACTOME pathways | R-HSA-69656 | 71 | 20 | 10287 | 1696 |
MAX,PSMB7,PSMA1,CUL1,PSMB9,PSMD9,PSMB3,PSMC4,PSMD2,RB1,PSMA6,CCNA2,PSMD1,RPS27A,PSMD3,PSMD8,CDKN1B,CDC25B,CDK2,PSMC1 |
| 9.122e-03 | -4.70 | protein localization to vacuole | biological process | GO:0072665 | 57 | 16 | 17256 | 2622 |
NAGPA,GCC2,SCARB2,LARS,HGS,TNFAIP3,RAB7A,LAMTOR4,VTI1A,CLU,VPS4A,CD81,SMURF1,BECN1,VPS25,SH3GLB1 |
| 9.122e-03 | -4.70 | lysosome organization | biological process | GO:0007040 | 57 | 16 | 17256 | 2622 |
NAGPA,RAB14,ACP2,PPT1,RAB7A,HEXB,NAGLU,ATP6V0C,CORO1A,CLN3,TMEM165,BECN1,CLN6,ABCA1,SNAPIN,TFEB |
| 9.122e-03 | -4.70 | lytic vacuole organization | biological process | GO:0080171 | 57 | 16 | 17256 | 2622 |
NAGPA,RAB14,ACP2,PPT1,RAB7A,HEXB,NAGLU,ATP6V0C,CORO1A,CLN3,TMEM165,BECN1,CLN6,ABCA1,SNAPIN,TFEB |
| 9.123e-03 | -4.70 | CTCNANGTGNY_UNKNOWN | MSigDB lists | CTCNANGTGNY_UNKNOWN | 77 | 20 | 17377 | 2626 |
HSPH1,MAX,REPS2,ZFP91,HNRNPF,SREK1,CTCF,CYFIP2,ZADH2,ADSS,SUGP1,SLC31A1,INPP5A,HDAC7,ALDH18A1,CITED2,ABCA1,IPO4,ATXN7L2,RBM15B |
| 9.123e-03 | -4.70 | CARD_MIR302A_TARGETS | MSigDB lists | CARD_MIR302A_TARGETS | 77 | 20 | 17377 | 2626 |
RORB,RB1CC1,EIF4G2,RB1,FBXO21,MBD2,JAZF1,ZNF367,LIMK1,E2F1,PPP6C,DDX5,TARDBP,KPNA2,NR2F2,RBBP4,CDK2,STAT3,DNMT1,ARID4A |
| 9.142e-03 | -4.69 | GSE43863_TH1_VS_LY6C_INT_CXCR5POS_EFFECTOR_CD4_TCELL_DN | MSigDB lists | GSE43863_TH1_VS_LY6C_INT_CXCR5POS_EFFECTOR_CD4_TCELL_DN | 194 | 42 | 17377 | 2626 |
ANKRD13D,ADD1,SF3B1,VAV2,SNX15,HABP4,ACAP1,CDC42SE2,ZNRF3,EZH1,GGPS1,FOXO3,PIP4K2A,PAIP2,PRKD3,ITGB8,ZCCHC2,ARHGEF1,FRMD8,ARID4A,SPTAN1,SP3,TEX10,PARP4,HSDL1,WDR82,MAP4K3,MTMR12,ARID1A,RHOT1,TANC1,EIF4G2,HSPA1B,ANKRD10,SCARB2,GOLGA4,BRWD1,DTX4,NCOA1,PDLIM5,ABCA1,SNX14 |
| 9.142e-03 | -4.69 | GSE43700_UNTREATED_VS_IL10_TREATED_PBMC_DN | MSigDB lists | GSE43700_UNTREATED_VS_IL10_TREATED_PBMC_DN | 194 | 42 | 17377 | 2626 |
NDUFV2,DNAJC2,GADD45G,SLC2A1,PTTG1,MRPS26,MOGS,ENSA,PLXNA1,EZH1,GGA2,C19orf48,PARK7,RPA2,CDK5,ATP6V0B,SLC1A4,SAR1A,AP3S2,DUT,ZNF326,SLC35C2,ABI1,LYPLA2,NTPCR,ERF,RPS10,SLBP,COG1,RIT1,DCUN1D5,ZFAND5,CYB5A,XRCC5,RAB18,MID1IP1,SNAP23,NFIL3,PITX1,RGL1,PREPL,B4GALT3 |
| 9.142e-03 | -4.69 | GSE360_CTRL_VS_B_MALAYI_HIGH_DOSE_MAC_DN | MSigDB lists | GSE360_CTRL_VS_B_MALAYI_HIGH_DOSE_MAC_DN | 194 | 42 | 17377 | 2626 |
EWSR1,TRIP10,MDH2,SNX15,CUL1,NCKAP1,RNF103,ZNF804A,TERF2IP,RAB8A,PDCD2,MDFIC,CLTB,TIPARP,SLC25A1,SRSF10,PPIF,CPNE1,PLK1,IFRD1,BRD4,TRAFD1,CIC,TOP3A,RCOR1,NFATC2IP,OGDH,NCDN,ZFR,RPA1,KRIT1,BRD2,RBL1,ZNF330,STAT6,HPS5,COX7A2L,PPM1G,KHSRP,SSNA1,PRPF4,RNF14 |
| 9.142e-03 | -4.69 | GSE18281_SUBCAPSULAR_CORTICAL_REGION_VS_WHOLE_CORTEX_THYMUS_UP | MSigDB lists | GSE18281_SUBCAPSULAR_CORTICAL_REGION_VS_WHOLE_CORTEX_THYMUS_UP | 194 | 42 | 17377 | 2626 |
SLC12A7,MIF4GD,NQO1,CASP6,ANKH,ANK3,GNE,MRPS26,CERK,LACTB2,EIF2AK4,MXD4,BRIX1,MAP1LC3B,SYNRG,ITGB5,EXT2,DECR1,SRI,CTR9,KDELR1,TSPYL4,CREG1,PRKDC,SLC16A7,NLN,PSMG1,CADM1,ANLN,CYFIP2,PRPSAP1,ATP1A1,SYNCRIP,TXNDC16,LTBP4,ACYP1,ZHX1,RGL1,RPS6KC1,CHPT1,PDCD4,SNAPIN |
| 9.142e-03 | -4.69 | GSE36527_CD69_NEG_VS_POS_TREG_CD62L_LOS_KLRG1_NEG_UP | MSigDB lists | GSE36527_CD69_NEG_VS_POS_TREG_CD62L_LOS_KLRG1_NEG_UP | 194 | 42 | 17377 | 2626 |
FAM208B,PARP12,TMEM184B,HLA-E,TOR3A,TOR1AIP1,PTTG1,GADD45G,CENPF,TAP1,CDC42SE2,RAPGEF6,CMTM6,IRF4,CLIC4,TPST1,ZBTB22,NUP153,STAT3,PPA1,MORC3,TRAFD1,DDX24,RAD51AP1,RPS10,TOR1AIP2,ASB13,OGFR,PSMB9,PLEKHF2,ISG15,TRAM2,TRIM26,KEAP1,ETS2,RBL1,STAT1,PML,CHMP4B,SLAIN1,RNF14,RNF114 |
| 9.142e-03 | -4.69 | GSE42021_TCONV_PLN_VS_TREG_PRECURSORS_THYMUS_DN | MSigDB lists | GSE42021_TCONV_PLN_VS_TREG_PRECURSORS_THYMUS_DN | 194 | 42 | 17377 | 2626 |
SLC12A7,OTUD5,UBE2D3,IER2,MAPRE1,SRGN,STARD7,YTHDF3,AGFG1,CCNL2,CSNK1A1,KCMF1,RNF103,CRKL,SLC31A1,MDM2,VASP,PSMA6,NEK6,HUWE1,TANK,ATP13A3,TRA2B,TARDBP,STAT3,SRSF10,IFRD1,CYFIP1,BIRC3,MAP4K4,ILF3,GTPBP4,TBRG4,PBRM1,DCUN1D5,KDM3A,RHOB,ETS2,PIAS2,ADAM9,TMEM159,B4GALT3 |
| 9.142e-03 | -4.69 | GOTZMANN_EPITHELIAL_TO_MESENCHYMAL_TRANSITION_DN | MSigDB lists | GOTZMANN_EPITHELIAL_TO_MESENCHYMAL_TRANSITION_DN | 194 | 42 | 17377 | 2626 |
SEPHS2,IER2,PIGQ,TKT,FKBP2,MAPK14,TMEM165,BCAP31,MAN1A1,PA2G4,PDCD2,AHCY,OSTF1,TCEA1,ATF2,SLC35A1,FDFT1,CLCN3,DDX24,AMD1,ARHGDIB,CAPZA2,VDAC1,ECH1,ARF4,CLNS1A,SRSF1,RAB18,MTHFD2,FNTA,DDOST,SNAP23,YWHAZ,ROCK1,ACADM,YWHAH,PSMC1,EYA2,PURA,TOB1,ANXA11,CDKN2A |
| 9.161e-03 | -4.69 | GSE14308_NAIVE_CD4_TCELL_VS_INDUCED_TREG_DN | MSigDB lists | GSE14308_NAIVE_CD4_TCELL_VS_INDUCED_TREG_DN | 183 | 40 | 17377 | 2626 |
MBD1,C1orf74,RHOG,GNPNAT1,TM9SF4,KDM4A,PRKCSH,FLYWCH2,ANKH,SIRT2,CMTM6,STRBP,SUV39H2,DPYSL2,MECR,NSFL1C,PTPN11,MINPP1,ATP6V0D1,SRSF10,TSTA3,DCAF8,HELB,METTL5,PSMA1,EXOSC9,USP22,PITPNB,API5,BORA,MAP2K2,TPD52L2,SPATA2,ATXN2L,WIPI2,NDUFS5,RBBP4,NDE1,SMARCD1,RHEBL1 |
| 9.161e-03 | -4.69 | GSE42021_TCONV_PLN_VS_CD24INT_TCONV_THYMUS_UP | MSigDB lists | GSE42021_TCONV_PLN_VS_CD24INT_TCONV_THYMUS_UP | 183 | 40 | 17377 | 2626 |
TCF12,MRPL9,TRIP12,SCOC,PTTG1,RBM8A,CERK,UBE2Z,FAM8A1,PARK7,UBLCP1,SF3B2,ATP6V0B,RAP1A,CLIC4,TBC1D14,MBD2,CRAT,CS,ANP32A,KIFAP3,SLC38A10,FDFT1,SRSF10,SPTAN1,RFC3,ELL2,WDR1,HAGH,ARF4,SRSF1,RAB18,UEVLD,WNT5B,MAP4,PPA2,LY75,ACADM,PTDSS1,SNX14 |
| 9.161e-03 | -4.69 | GSE2770_IL12_ACT_VS_ACT_CD4_TCELL_2H_DN | MSigDB lists | GSE2770_IL12_ACT_VS_ACT_CD4_TCELL_2H_DN | 183 | 40 | 17377 | 2626 |
WSB2,PDCD6IP,DYNLL1,TRIO,ATP6V1B2,PSEN1,CFLAR,ZER1,RBM23,PSMD1,ITGB8,TANK,TXLNA,ZNF200,ANAPC7,ABCC1,ADAM17,CREG1,RAB7A,CRNKL1,DNAJA1,CHMP2B,RAB1A,EML4,BSDC1,FADD,NEU1,NMT2,PSMC4,C1orf122,OSBPL11,SLC38A7,TWSG1,ITGB1,ST3GAL2,PDXK,ATP6V1C1,PSMC1,ATP6V0E1,STARD3NL |
| 9.161e-03 | -4.69 | GSE411_WT_VS_SOCS3_KO_MACROPHAGE_IL6_STIM_400MIN_DN | MSigDB lists | GSE411_WT_VS_SOCS3_KO_MACROPHAGE_IL6_STIM_400MIN_DN | 183 | 40 | 17377 | 2626 |
GLT8D1,MTX3,MRPL39,CAST,TRMT6,MOGS,GGA2,ELMOD2,RAPGEF6,NAPG,CTSS,ZNF639,DNAAF2,ZNF746,COPS7B,CABLES2,GEMIN4,GPD1L,ZNF770,NRAS,PPT1,HNRNPF,SMU1,MCL1,FANCE,MAPK3,YIF1A,SGSH,HGS,PCM1,ZC3H7B,DTX4,AEN,ZFP90,MAP3K5,SMAD1,MYO9A,GLCCI1,ABCA1,HDAC2 |
| 9.215e-03 | -4.69 | SET | pfam domains | PF00856 | 39 | 12 | 17054 | 2545 |
ASH1L,KMT5C,SUV39H2,KMT2E,KMT5A,SETD3,EHMT1,KMT2B,NSD3,EZH1,KMT2C,PRDM11 |
| 9.225e-03 | -4.69 | ATP6V1B1 (ATPase H+ transporting V1 subunit B1) | protein interactions | 525 | 96 | 25 | 17029 | 2761 |
INTS2,CCT2,DNAJC5,PKP4,GBA,FLOT1,ATP6V0A1,ATP6V1B2,CHMP2B,RAB22A,TFRC,MRPL50,SCARB2,ATP6V1D,RALB,RAB35,BANF1,WDR7,ATP6V0A2,CHMP4B,ATP6V1C1,HNRNPDL,ATP6V0D1,SVIP,ATP6V1G1 |
| 9.274e-03 | -4.68 | coenzyme metabolic process | biological process | GO:0006732 | 311 | 63 | 17256 | 2622 |
GALK1,NADSYN1,PPCS,SUCLG1,MDH2,SLC2A1,MCCC1,TKT,PM20D2,ADPGK,SPR,PMVK,FLAD1,MAT2B,PDXP,GART,COQ4,ATIC,PPCDC,SUCLG2,AHCY,TECR,AHCYL1,TALDO1,GPD1L,KCNAB2,RNLS,SLC25A1,LDHB,ACSL5,ELOVL5,ATP5IF1,PPT1,COQ8A,COQ10B,ACSL3,AMD1,LDHA,NADK2,OGDH,PKM,PDHX,MPC1,CYB5A,MAT2A,SLC19A1,MBIP,MTHFD2,DBI,ACLY,NAXE,ACAT1,DHTKD1,MLYCD,MDH1,GPI,PDXK,DHFR2,PARP10,PGAM1,ACSF2,PDSS2,PFKP |
| 9.358e-03 | -4.67 | autophagy of mitochondrion | biological process | GO:0000422 | 43 | 13 | 17256 | 2622 |
ATG9A,RB1CC1,ATG3,FBXO7,ATG13,ATG2B,CISD2,WIPI2,WDR45B,BECN1,MAP1LC3B,MARK2,ATG4A |
| 9.358e-03 | -4.67 | mitochondrion disassembly | biological process | GO:0061726 | 43 | 13 | 17256 | 2622 |
ATG9A,RB1CC1,ATG3,FBXO7,ATG13,ATG2B,CISD2,WIPI2,WDR45B,BECN1,MAP1LC3B,MARK2,ATG4A |
| 9.361e-03 | -4.67 | VEGF signaling pathway | KEGG pathways | ko04370 | 59 | 17 | 7161 | 1149 |
PPP3CA,NRAS,MAPKAPK3,RAF1,AKT2,RAC1,NFATC2,KRAS,PPP3CB,MAPK14,MAP2K2,MAPK3,CDC42,PIK3R2,PPP3R1,MAPK1,HRAS |
| 9.361e-03 | -4.67 | Lysine degradation | KEGG pathways | hsa00310 | 59 | 17 | 7161 | 1149 |
ASH1L,KMT2E,EHMT1,NSD3,OGDH,EZH1,KMT2C,DOT1L,SUV39H2,KMT5C,SETD3,KMT5A,CAMKMT,KMT2B,ACAT1,PLOD3,ALDH9A1 |
| 9.361e-03 | -4.67 | VEGF signaling pathway | KEGG pathways | hsa04370 | 59 | 17 | 7161 | 1149 |
PPP3CA,NRAS,MAPKAPK3,RAF1,AKT2,RAC1,NFATC2,KRAS,PPP3CB,MAPK14,MAP2K2,MAPK3,CDC42,PIK3R2,PPP3R1,MAPK1,HRAS |
| 9.361e-03 | -4.67 | Lysine degradation | KEGG pathways | ko00310 | 59 | 17 | 7161 | 1149 |
ASH1L,KMT2E,EHMT1,NSD3,OGDH,EZH1,KMT2C,DOT1L,KMT5C,SUV39H2,SETD3,KMT5A,CAMKMT,KMT2B,ACAT1,PLOD3,ALDH9A1 |
| 9.363e-03 | -4.67 | RPS10P5 (ribosomal protein S10 pseudogene 5) | protein interactions | 93144 | 32 | 11 | 17029 | 2761 |
NAP1L1,NQO1,RPL17,RPS27A,RPL6,RPS24,RPL15,NDUFA7,SLC25A5,RPS26,RPL23A |
| 9.363e-03 | -4.67 | FOXRED2 (FAD dependent oxidoreductase domain containing 2) | protein interactions | 80020 | 32 | 11 | 17029 | 2761 |
DNAJC10,GALK1,RPN1,TXNDC16,PRKDC,VDAC2,SEL1L,FEM1B,TOMM40,VDAC1,NIPSNAP1 |
| 9.363e-03 | -4.67 | CHGB (chromogranin B) | protein interactions | 1114 | 32 | 11 | 17029 | 2761 |
UBTF,FGFR3,TK1,PTEN,MOGS,TWF2,CBFB,SAFB2,TAZ,APP,OGG1 |
| 9.363e-03 | -4.67 | PHF20L1 (PHD finger protein 20 like 1) | protein interactions | 51105 | 32 | 11 | 17029 | 2761 |
LIN9,LYAR,KPNA4,CHD3,MTA1,MTA2,MBD2,RNASEH2A,MBD3,APP,HDAC2 |
| 9.363e-03 | -4.67 | TRMT1L (tRNA methyltransferase 1 like) | protein interactions | 81627 | 32 | 11 | 17029 | 2761 |
NTPCR,FOXM1,MECP2,DCTN2,CBWD1,TARDBP,TCEA1,MAPK14,APP,CDC5L,CAND1 |
| 9.363e-03 | -4.67 | REPIN1 (replication initiator 1) | protein interactions | 29803 | 32 | 11 | 17029 | 2761 |
POLA2,ZNF672,HGS,RPS2,DGCR8,SUZ12,KCTD17,CDC23,HDAC2,RBM15B,TERF2 |
| 9.363e-03 | -4.67 | FAM98B (family with sequence similarity 98 member B) | protein interactions | 283742 | 32 | 11 | 17029 | 2761 |
CYLD,IDE,PPP1R8,RTCB,CUL3,GORASP2,MCM2,C2orf49,CD81,EIF4H,CAND1 |
| 9.363e-03 | -4.67 | SF3B5 (splicing factor 3b subunit 5) | protein interactions | 83443 | 32 | 11 | 17029 | 2761 |
SF3B1,SF3B6,COPE,ILF3,NIPSNAP2,SGF29,SF3A2,SNRPA,SMNDC1,IWS1,SF3B2 |
| 9.363e-03 | -4.67 | LHX4 (LIM homeobox 4) | protein interactions | 89884 | 32 | 11 | 17029 | 2761 |
WASF2,SNRNP25,CYFIP1,ARID2,LDB1,ZNF574,CHCHD2,CYFIP2,ABI1,SMAD4,DCAF5 |
| 9.366e-03 | -4.67 | Defective CFTR causes cystic fibrosis | REACTOME pathways | R-HSA-5678895 | 62 | 18 | 10287 | 1696 |
PSMA8,ERLIN1,PSMB7,PSMA1,PSMB9,PSMD9,PSMB3,PSMC4,DERL1,PSMD2,PSMA6,PSMD1,RPS27A,PSMD3,PSMD8,SEL1L,PSMC1,RNF5 |
| 9.392e-03 | -4.67 | cellular response to hydrogen peroxide | biological process | GO:0070301 | 62 | 17 | 17256 | 2622 |
PPIF,TNFAIP3,NQO1,NET1,PRKAA1,BECN1,ETS1,PARK7,RHOB,ANKZF1,PCNA,MDM2,PDCD10,STAT6,PPP5C,MAP3K5,HDAC2 |
| 9.398e-03 | -4.67 | EXOC1 (exocyst complex component 1) | protein interactions | 55763 | 101 | 26 | 17029 | 2761 |
CCDC93,EXOC3,RB1CC1,TRIO,KIAA1551,NUP54,SIKE1,NUF2,IKBIP,MACF1,GIT2,DST,SH3BP5,KIF5B,GOLGA4,GRIPAP1,CCDC6,RALB,SNAP29,RABGAP1L,EXOC4,TRIM32,LUC7L2,CDC5L,SPTAN1,SNAPIN |
| 9.398e-03 | -4.67 | SLC39A4 (solute carrier family 39 member 4) | protein interactions | 55630 | 101 | 26 | 17029 | 2761 |
NDC1,GOLIM4,GPR89A,MRS2,VPS45,LETMD1,LRRC8A,ABCB10,SLC4A2,SLC35B2,PDE3B,PTPN2,GOLM1,MAN2A2,LEMD2,SLC1A4,ORMDL2,FUT8,HADHB,UQCRH,ABCD1,CISD2,METTL9,MGAT5,AAAS,MFSD12 |
| 9.404e-03 | -4.67 | HA2 | smart domains | SM00847 | 18 | 7 | 9493 | 1367 |
DHX8,DHX16,DHX29,DHX15,DHX57,YTHDC2,DHX9 |
| 9.429e-03 | -4.66 | magnesium ion transmembrane transporter activity | molecular function | GO:0015095 | 17 | 7 | 17224 | 2647 |
NIPAL3,NIPA2,MAGT1,SLC41A1,NIPA1,MRS2,ZDHHC13 |
| 9.429e-03 | -4.66 | protein transmembrane transporter activity | molecular function | GO:0008320 | 17 | 7 | 17224 | 2647 |
MCL1,SEC61B,TOMM20,TOMM40,SEC61G,TIMM23,TIMM17A |
| 9.429e-03 | -4.66 | histone methyltransferase activity (H3-K4 specific) | molecular function | GO:0042800 | 17 | 7 | 17224 | 2647 |
KMT2B,WDR82,ASH1L,KMT2C,WDR5,CXXC1,SETD3 |
| 9.429e-03 | -4.66 | Translesion synthesis by REV1 | REACTOME pathways | R-HSA-110312 | 16 | 7 | 10287 | 1696 |
RPA2,PCNA,RFC3,RFC2,RPS27A,MAD2L2,RPA1 |
| 9.429e-03 | -4.66 | STING mediated induction of host immune responses | REACTOME pathways | R-HSA-1834941 | 16 | 7 | 10287 | 1696 |
IRF3,CGAS,STAT6,PRKDC,IFI16,XRCC5,DTX4 |
| 9.435e-03 | -4.66 | GSE21033_1H_VS_24H_POLYIC_STIM_DC_UP | MSigDB lists | GSE21033_1H_VS_24H_POLYIC_STIM_DC_UP | 156 | 35 | 17377 | 2626 |
RMND5A,HIVEP3,TCF12,ARID2,STRN4,PTP4A3,MEF2A,PPP1R16B,ATP13A3,ANXA5,TTPAL,BRD4,TACC1,USP42,MIER1,PFKFB3,NFATC2,MCL1,DCLRE1C,ICAM2,CYFIP2,CBFA2T2,TOLLIP,PTPRF,VEZF1,OSBPL11,TTC13,TPP2,ARNTL,PTPN7,CAB39,CNOT6,PSAP,TCOF1,TMEM131 |
| 9.435e-03 | -4.66 | GSE21927_UNTREATED_VS_GMCSF_IL6_TREATED_BONE_MARROW_UP | MSigDB lists | GSE21927_UNTREATED_VS_GMCSF_IL6_TREATED_BONE_MARROW_UP | 156 | 35 | 17377 | 2626 |
UBL3,COX15,GMFG,PPP1R12A,RAB11B,SRSF6,SLC35B2,ETS1,EPM2A,CAPN2,TMEM69,RALB,TIMM23,FAM89B,RNF135,RBM12B,ATF2,CTDSP2,HP1BP3,RAD51AP1,TMEM216,ILF3,VDAC2,HERPUD2,MACF1,CAND1,PON2,TMEM168,UBXN2B,MAPK6,PPM1G,FKBP5,YWHAZ,TFDP2,ADNP2 |
| 9.439e-03 | -4.66 | regulation of kinase activity | biological process | GO:0043549 | 892 | 161 | 17256 | 2622 |
CCNC,FGFR1OP,TXN,TSC2,MAP3K7CL,NF1,CCNL2,CCNB1,S1PR2,MAPK14,PARK7,PRNP,CALM2,CDK5,CDKN2C,RAP1A,PIK3R2,CDC25B,MLST8,CDC37,PLK1,COPS8,BAK1,NCK1,GMFB,MRNIP,CDC6,UBE2V1,LRP5,MAP3K4,HHEX,RPS27A,AXIN1,SOCS4,CAB39,ADAM9,STK11,CLU,DVL1,PDCD4,HSPH1,CLSPN,GMFG,GADD45G,PRKAA1,VAV2,CIB1,LAMTOR3,RGS2,PSEN1,VPS25,TFAP4,RB1,TIGAR,FBXO7,MDFIC,PIK3IP1,MVP,MCPH1,GNAI2,SOCS5,MAPKAPK3,LDB1,GTPBP4,GBA,KRAS,MAP4K3,ADRB2,MAP2K2,XRCC5,TSC1,MBIP,DUSP3,CSK,QARS,NLRC5,NUP62,MAP3K5,ALS2,CDKN2A,BCCIP,KARS,GGNBP2,TRAF7,RAF1,MAGED1,TPX2,DAZAP2,PRKACA,LYN,DUSP22,APP,CRKL,SHC1,RALB,KIF14,ADCY9,SOCS6,CDKN1B,F2R,ABI1,CDK12,DVL2,CHP1,ADCY7,PSRC1,TAOK1,MAP4K4,ELP4,DNAJA1,PKMYT1,SOCS7,PPP2CA,PPP2R5A,TAB2,RBL1,STK38,CORO1C,GADD45B,RPLP1,MAPK1,LRP8,MIF,ZFP91,AKT1S1,BLM,PTPN2,CCNK,FGFR3,PDCD10,PTEN,PTPN11,DUS2,H2AFY,ATG13,MAP3K14,TGFB1,PDPK1,TELO2,RHOA,ADAM17,TNFAIP3,PRKAR1B,JTB,WDR81,MEN1,MARK2,MAPK3,SH3BP5,NEK1,HGS,GPS2,PRDX3,OSBPL8,PKD2,NR2F2,WDR91,CD81,HRAS,HIPK3,FAF1 |
| 9.440e-03 | -4.66 | human chr5q13.3 | chromosome location | human chr5q13.3 | 29 | 8 | 26185 | 2809 |
ZBED3,NSA2,AGGF1,POLK,HEXB,F2R,GFM2,POC5 |
| 9.449e-03 | -4.66 | PSME1 (proteasome activator subunit 1) | protein interactions | 5720 | 77 | 21 | 17029 | 2761 |
TK1,PSRC1,PSMB7,PSMA1,USP22,MCM2,PSMB9,APP,PSMB3,PSMC4,USP5,KIF5B,PSMA6,PSMD1,HUWE1,PRDX3,CHD3,FBXO7,RNF26,PSMC1,CDC37 |
| 9.449e-03 | -4.66 | E4F1 (E4F transcription factor 1) | protein interactions | 1877 | 77 | 21 | 17029 | 2761 |
ZCCHC9,MRPS2,PRKDC,SF3B1,ZNF574,RPS24,CSNK2A1,NSA2,RB1,DAP3,UPF1,LTBP4,RPS27A,ANP32A,YBX1,UPF2,RPL19,ZBTB11,ZNF770,CDKN2A,ZBTB24 |
| 9.449e-03 | -4.66 | GLMN (glomulin, FKBP associated protein) | protein interactions | 11146 | 77 | 21 | 17029 | 2761 |
ANKLE2,BIRC3,RBX1,CUL3,CUL1,IRF3,BIRC2,BTBD1,DHX57,EVC2,FKBP1A,DTL,SCARB2,NSFL1C,ARRDC1,FEM1B,FKBP5,RP2,KLHL42,ZSWIM6,CDC37 |
| 9.449e-03 | -4.66 | HSPA1B (heat shock protein family A (Hsp70) member 1B) | protein interactions | 3304 | 77 | 21 | 17029 | 2761 |
STAU1,NPHP4,CYLD,CUL3,CUL1,ADRB2,UBQLN2,CAND1,DERL1,PA2G4,FGFR3,HSPBP1,SHC1,BANF1,PIK3R2,YWHAZ,FNIP2,COPS6,PPP5C,SMURF1,ARRB2 |
| 9.449e-03 | -4.66 | DOCK7 (dedicator of cytokinesis 7) | protein interactions | 85440 | 77 | 21 | 17029 | 2761 |
USP7,STAU1,TK1,PPP1R18,RHOA,MYH9,NSD3,IRF3,AURKB,BCL2L1,CAPZA2,CRLF3,TSC1,CDC42,YWHAZ,MOB1A,CDK2,YWHAH,LPCAT1,IFI16,LRCH1 |
| 9.459e-03 | -4.66 | Homologous recombination | KEGG pathways | ko03440 | 41 | 13 | 7161 | 1149 |
RPA2,RAD51C,BABAM2,PALB2,BABAM1,XRCC2,TOP3A,XRCC3,BRCA1,BLM,RAD51D,RPA1,RAD54B |
| 9.459e-03 | -4.66 | Homologous recombination | KEGG pathways | hsa03440 | 41 | 13 | 7161 | 1149 |
RPA2,RAD51C,BABAM2,PALB2,XRCC2,BABAM1,TOP3A,XRCC3,BRCA1,BLM,RAD51D,RAD54B,RPA1 |
| 9.466e-03 | -4.66 | N-acetyltransferase activity | molecular function | GO:0008080 | 86 | 22 | 17224 | 2647 |
GNPNAT1,KAT2A,KAT7,ELP4,EDF1,TAF6L,USP22,WDR5,SUPT7L,TEX30,OGT,NAA50,TAF5L,KANSL2,TAF12,NCOA1,NAA20,ATF2,SMARCE1,NAA35,SAT2,NAA60 |
| 9.484e-03 | -4.66 | ARPC1B (actin related protein 2/3 complex subunit 1B) | protein interactions | 10095 | 63 | 18 | 17029 | 2761 |
METTL1,DHPS,ACTR3,MYH9,RANGAP1,CAPZA2,APP,RPA2,TPD52L2,WAS,ARPC5,MYO18A,BTF3L4,ANP32A,ACTB,CDK2,PDCD4,SRPK2 |
| 9.484e-03 | -4.66 | VSIG4 (V-set and immunoglobulin domain containing 4) | protein interactions | 11326 | 63 | 18 | 17029 | 2761 |
SLC30A9,PDK2,RAB18,INTS7,WDR44,NF1,TIMM29,PIK3R2,ATP2C1,TIGD5,UPK3BL1,XRCC3,CDC42SE2,UBE3C,AP3S1,APP,XPR1,ZNF146 |
| 9.484e-03 | -4.66 | BCL7C (BCL tumor suppressor 7C) | protein interactions | 9274 | 63 | 18 | 17029 | 2761 |
PHF10,ATXN3,ARID2,SMARCA4,NSD3,ARID1A,PBRM1,TWF2,ARID1B,APP,TIMM13,NEIL3,BANF1,BRD7,ACTB,SMARCE1,BRD9,SMARCD1 |
| 9.484e-03 | -4.66 | UBE2C (ubiquitin conjugating enzyme E2 C) | protein interactions | 11065 | 63 | 18 | 17029 | 2761 |
UBE2D3,UNK,UBQLN4,UBXN1,ANAPC2,UBE2V1,UBE4B,ATP6V1B2,TRIM28,TTC9C,PPM1G,ZRANB2,TAGLN2,TTLL12,AHCYL1,UBE2C,SSSCA1,USP34 |
| 9.484e-03 | -4.66 | RAB5B (RAB5B, member RAS oncogene family) | protein interactions | 5869 | 63 | 18 | 17029 | 2761 |
NDUFS1,RAB11B,RAB7A,TUFM,LAGE3,DHX9,ARF1,RAB1A,REEP5,RAB11A,TFRC,RAB2B,RAB8A,RPN1,RAP1A,TBC1D17,ARF5,NDUFS8 |
| 9.484e-03 | -4.66 | KDM5B (lysine demethylase 5B) | protein interactions | 10765 | 63 | 18 | 17029 | 2761 |
BRD4,KLF10,MTA2,RCOR1,KRAS,MBD3,ARID1B,TAF2,RB1,CHD3,HDAC7,MBD2,AXIN2,PRPF4,RBBP4,CBX4,HDAC2,RBM15B |
| 9.484e-03 | -4.66 | PJA1 (praja ring finger ubiquitin ligase 1) | protein interactions | 64219 | 63 | 18 | 17029 | 2761 |
UBE2D3,USP7,NSMCE4A,ATXN3,DNAJB2,SUZ12,MAGED1,SMC6,STAM,USP36,USP5,MDM2,UCHL5,USP20,JOSD1,KIF22,TALDO1,ESPL1 |
| 9.484e-03 | -4.66 | ATG7 (autophagy related 7) | protein interactions | 10533 | 63 | 18 | 17029 | 2761 |
NASP,SNX2,KIAA0930,GSPT2,MAN2B1,PPP3CB,MAP1LC3B,GFER,APP,MAT2B,ATG3,STAT1,MICU2,ANP32E,FKBP5,CLN3,ATP6V1C1,EEF1D |
| 9.489e-03 | -4.66 | maturation of 5.8S rRNA | biological process | GO:0000460 | 34 | 11 | 17256 | 2622 |
KRI1,UTP20,NSA2,EXOSC7,RRP15,EXOSC9,RRS1,PDCD11,MAK16,FTSJ3,RPSA |
| 9.489e-03 | -4.66 | protein depolymerization | biological process | GO:0051261 | 34 | 11 | 17256 | 2622 |
KIF2A,KIF18A,KIF18B,WDR1,KIF14,KIF2C,VPS4A,TWF2,STMN1,MICAL3,CFL1 |
| 9.494e-03 | -4.66 | Eea1 (early endosome antigen 1) | protein interactions | 216238 | 20 | 8 | 17029 | 2761 |
NLN,KRAS,NPHP4,RB1CC1,PSPC1,ANAPC4,ASF1B,WWP2 |
| 9.494e-03 | -4.66 | FBH1 (F-box DNA helicase 1) | protein interactions | 84893 | 20 | 8 | 17029 | 2761 |
DTL,CUL1,RPA2,PCNA,SYNCRIP,RBX1,ILKAP,RPA1 |
| 9.494e-03 | -4.66 | ALDH16A1 (aldehyde dehydrogenase 16 family member A1) | protein interactions | 126133 | 20 | 8 | 17029 | 2761 |
MDM2,UGP2,ATIC,MEA1,KHSRP,LANCL1,PFKP,FAS |
| 9.494e-03 | -4.66 | BEND5 (BEN domain containing 5) | protein interactions | 79656 | 20 | 8 | 17029 | 2761 |
USP20,USP7,GORASP2,UBE2I,VPS25,APP,EIF3D,BUD31 |
| 9.494e-03 | -4.66 | MPI (mannose phosphate isomerase) | protein interactions | 4351 | 20 | 8 | 17029 | 2761 |
MIF,SRI,TIA1,NANS,PITPNB,PCBP1,APP,NECAP2 |
| 9.494e-03 | -4.66 | PAEP (progestagen associated endometrial protein) | protein interactions | 5047 | 20 | 8 | 17029 | 2761 |
DDOST,ZFP91,BANF1,SLC25A12,COPS6,APP,IFI16,ESYT2 |
| 9.494e-03 | -4.66 | HIST1H2AA (histone cluster 1 H2A family member a) | protein interactions | 221613 | 20 | 8 | 17029 | 2761 |
RAD18,MCM2,EIF4A3,MCM5,RPS14,RPSA,HDAC2,DOT1L |
| 9.494e-03 | -4.66 | TMEM126B (transmembrane protein 126B) | protein interactions | 55863 | 20 | 8 | 17029 | 2761 |
NDUFS1,TIMMDC1,SUGP2,DHX9,MRFAP1L1,APP,GLMP,DHX15 |
| 9.494e-03 | -4.66 | DSCC1 (DNA replication and sister chromatid cohesion 1) | protein interactions | 79075 | 20 | 8 | 17029 | 2761 |
PCNA,RFC3,THOC1,CHTF18,SLC22A23,CDIPT,RFC2,GTF2F1 |
| 9.494e-03 | -4.66 | SPIB (Spi-B transcription factor) | protein interactions | 6689 | 20 | 8 | 17029 | 2761 |
IRF4,RB1,E2F4,E2F1,E2F3,CSNK2A1,E2F2,MAPK3 |
| 9.494e-03 | -4.66 | Kif1c (kinesin family member 1C) | protein interactions | 16562 | 20 | 8 | 17029 | 2761 |
AHCY,SUB1,THRAP3,ARF1,CHTOP,EIF4A3,PRKAA1,ADNP2 |
| 9.494e-03 | -4.66 | Dctn2 (dynactin 2) | protein interactions | 69654 | 20 | 8 | 17029 | 2761 |
KIF23,GOLM1,TRIM47,CAPZA2,SHCBP1,DCTN2,DCTN1,CAPZA1 |
| 9.494e-03 | -4.66 | SLC38A2 (solute carrier family 38 member 2) | protein interactions | 54407 | 20 | 8 | 17029 | 2761 |
UNK,CDC42,TMEM216,FLOT1,COX5A,CHMP4B,APP,TSPAN5 |
| 9.494e-03 | -4.66 | DIRAS3 (DIRAS family GTPase 3) | protein interactions | 9077 | 20 | 8 | 17029 | 2761 |
TGFB1,BRMS1,MDM2,FEZ2,RHOA,PALB2,KRAS,CHEK2 |
| 9.494e-03 | -4.66 | DCAF12 (DDB1 and CUL4 associated factor 12) | protein interactions | 25853 | 20 | 8 | 17029 | 2761 |
GOLIM4,COPS6,MCMBP,BIRC2,DDA1,YY1AP1,DDB1,XIAP |
| 9.494e-03 | -4.66 | TRAM1 (translocation associated membrane protein 1) | protein interactions | 23471 | 20 | 8 | 17029 | 2761 |
DERL1,TICAM1,MBOAT1,SEC61B,VKORC1,APP,BCAP31,HLA-A |
| 9.494e-03 | -4.66 | TUT7 (terminal uridylyl transferase 7) | protein interactions | 79670 | 20 | 8 | 17029 | 2761 |
PLK1,TIMM13,POLK,ZNF512,SLBP,APP,CCDC59,QSOX2 |
| 9.494e-03 | -4.66 | ORF10 (ORF10) | protein interactions | 4961456 | 20 | 8 | 17029 | 2761 |
RAE1,AGO2,CS,YTHDF3,BOLA1,NUP62,AKT1S1,SEH1L |
| 9.494e-03 | -4.66 | RMI1 (RecQ mediated genome instability 1) | protein interactions | 80010 | 20 | 8 | 17029 | 2761 |
RPA2,DCAF15,FAAP100,RMI2,TOP3A,CCDC69,BLM,RPA1 |
| 9.499e-03 | -4.66 | RNGTGGGC_UNKNOWN | MSigDB lists | RNGTGGGC_UNKNOWN | 721 | 132 | 17377 | 2626 |
NPHP4,ST13,UBE2Z,KIF2C,PPP1R16B,SYNRG,ANKRD39,CALM2,DPYSL2,UPRT,OGG1,NRAS,KLF10,CELSR2,PPFIA3,SOX4,SLC50A1,RAB22A,ZMYM3,MAN2A2,AHNAK,FBXO28,E2F4,SH3GLB2,ATXN2L,BCL7C,B4GALT2,EWSR1,LIME1,GGA1,RRM1,B4GALT1,SLC4A2,PPP3CB,XPNPEP3,XPO7,RTKN,FAM192A,LRRC8D,MEGF8,MRPL40,ANKHD1,KDELR1,MORC3,SOCS5,C16orf72,SRSF5,ELK1,PSMB3,NCDN,HMGN2,GNAS,MOSPD3,ZNF777,SYNCRIP,ODF2,ERGIC3,PRPS2,DNMT3A,TRERF1,DYNLL1,HCFC1R1,ZADH2,DUSP22,APP,SAP130,CSDE1,NRF1,CD3EAP,UTP18,WDR44,TNPO2,CGGBP1,DVL2,DCTN1,KDM3B,SNX25,ERF,KAT7,E2F3,LRRC8A,PFKFB3,RAD54B,SUPT16H,ALKBH6,RAB24,CORO1C,SAFB,STAT6,AP1S1,FKBP5,H3F3A,SLC25A39,ATXN7L2,OTUD5,PKP4,ANKRD13D,ATG2B,HMGN3,MYNN,AP3S1,RAB11A,WWP2,ADD3,ITGB8,RRBP1,LDLRAD3,CITED2,ST8SIA2,OSTC,RNF5,SLC25A1,SPTAN1,PDLIM2,AMPD2,ELOVL5,NUDT8,LONRF3,POLK,ZMYM5,PACS1,WDR81,KLF6,PICALM,POLR2A,TFEB,NUCB1,E2F1,CCDC69,DUSP11,MBD6,VPS29 |
| 9.505e-03 | -4.66 | UPF0034 | prosite domains | PS01136 | 4 | 3 | 12060 | 1670 |
DUS3L,DUS4L,DUS2 |
| 9.505e-03 | -4.66 | SEP | prosite domains | PS51399 | 4 | 3 | 12060 | 1670 |
UBXN2A,UBXN2B,NSFL1C |
| 9.519e-03 | -4.65 | central_nervous_system-cerebral_cortex-glioma-astrocytoma_Grade_II | COSMIC cancer mutations | central_nervous_system-cerebral_cortex-glioma-astrocytoma_Grade_II | 10 | 5 | 17385 | 2587 |
KRAS,NRAS,H3F3A,HRAS,CDKN2A |
| 9.519e-03 | -4.65 | skin-abdomen-malignant_melanoma-superficial_spreading | COSMIC cancer mutations | skin-abdomen-malignant_melanoma-superficial_spreading | 10 | 5 | 17385 | 2587 |
KRAS,STK11,NRAS,HRAS,CDKN2A |
| 9.519e-03 | -4.65 | skin-shoulder-malignant_melanoma-superficial_spreading | COSMIC cancer mutations | skin-shoulder-malignant_melanoma-superficial_spreading | 10 | 5 | 17385 | 2587 |
KRAS,STK11,NRAS,HRAS,CDKN2A |
| 9.519e-03 | -4.65 | cervical_intraepithelial_neoplasia_Grade_III | COSMIC cancer mutations | cervical_intraepithelial_neoplasia_Grade_III | 10 | 5 | 17385 | 2587 |
FGFR3,NRAS,PTEN,HRAS,CDKN2A |
| 9.519e-03 | -4.65 | intradermal | COSMIC cancer mutations | intradermal | 10 | 5 | 17385 | 2587 |
FGFR3,KRAS,NRAS,HRAS,CDKN2A |
| 9.519e-03 | -4.65 | cervix-in_situ_neoplasm-cervical_intraepithelial_neoplasia_Grade_III | COSMIC cancer mutations | cervix-in_situ_neoplasm-cervical_intraepithelial_neoplasia_Grade_III | 10 | 5 | 17385 | 2587 |
FGFR3,NRAS,PTEN,HRAS,CDKN2A |
| 9.533e-03 | -4.65 | HIST2H2AC (histone cluster 2 H2A family member c) | protein interactions | 8338 | 106 | 27 | 17029 | 2761 |
USP7,KAT2A,UBR2,KAT7,MECP2,USP10,CTCF,AURKB,BRCA1,SMC2,PBRM1,USP22,MCM2,APP,MCM5,STK38,H2AFX,ANP32A,PRMT7,NAP1L4,RRS1,RBBP4,PARP10,DNMT1,RNF169,HDAC2,SSRP1 |
| 9.546e-03 | -4.65 | GSE2770_TGFB_AND_IL4_VS_IL4_TREATED_ACT_CD4_TCELL_6H_UP | MSigDB lists | GSE2770_TGFB_AND_IL4_VS_IL4_TREATED_ACT_CD4_TCELL_6H_UP | 167 | 37 | 17377 | 2626 |
PKP4,FOXM1,SHPRH,TRAK1,TGOLN2,POFUT1,DDRGK1,USP5,MCTS1,KRI1,DUS4L,MCM5,SSBP3,MTA1,UBA5,GMEB1,MYBL1,DRAM2,EBAG9,B3GALT6,ZNF559,SNRNP200,SIGMAR1,TLK1,RFFL,MAP2K2,PSMB3,TSC1,WAS,SMAD2,GRIPAP1,CCDC14,EIF2D,NDUFA11,PPA2,PRMT7,OSGEPL1 |
| 9.550e-03 | -4.65 | Kinesin_motor_dom_sf | interpro domains | IPR036961 | 78 | 20 | 18492 | 2768 |
KIF3B,KIF15,KIF23,MYH9,MYO9B,KIF2C,KIF11,MYO1F,KIF5B,KIF2A,KIFC1,STARD9,KIF18A,KIF18B,KIF13B,KIF14,MYO18A,KIF22,MYO9A,MYO5A |
| 9.561e-03 | -4.65 | GO_CAJAL_BODY | MSigDB lists | GO_CAJAL_BODY | 48 | 14 | 17377 | 2626 |
OIP5,SART1,ZNF473,FAM118B,EFTUD2,PRPF4,PRPF3,FBL,CDK2,GAR1,COIL,LSG1,SMNDC1,DDX42 |
| 9.561e-03 | -4.65 | PID_CERAMIDE_PATHWAY | MSigDB lists | PID_CERAMIDE_PATHWAY | 48 | 14 | 17377 | 2626 |
RB1,BIRC3,RAF1,MAP4K4,ASAH1,CYCS,PAWR,BCL2,EIF2A,PRKRA,MAPK1,MAP2K2,FADD,MAPK3 |
| 9.574e-03 | -4.65 | negative regulation of kinase activity | biological process | GO:0033673 | 283 | 58 | 17256 | 2622 |
FGFR1OP,GGNBP2,TSC2,GMFG,NF1,CIB1,AKT1S1,RGS2,LYN,DUSP22,PSEN1,VPS25,PARK7,PTPN2,TFAP4,CDKN2C,RB1,PTEN,FBXO7,SOCS6,DUS2,H2AFY,CDKN1B,PIK3IP1,MVP,SOCS5,CHP1,PLK1,PDPK1,TNFAIP3,NCK1,PRKAR1B,GBA,GMFB,LRP5,DNAJA1,MEN1,SOCS7,PPP2CA,SH3BP5,HHEX,MBIP,PPP2R5A,GPS2,DUSP3,CSK,PRDX3,CORO1C,QARS,STK38,GADD45B,SOCS4,NUP62,DVL1,NR2F2,HIPK3,PDCD4,CDKN2A |
| 9.582e-03 | -4.65 | GSE37605_C57BL6_VS_NOD_FOXP3_IRES_GFP_TREG_DN | MSigDB lists | GSE37605_C57BL6_VS_NOD_FOXP3_IRES_GFP_TREG_DN | 189 | 41 | 17377 | 2626 |
GPR132,TRIP12,WDTC1,XIAP,CHIC2,NIPA2,MAPK14,RAPGEF6,FAM8A1,GIT2,MIS12,PPP1R8,ZNF260,ARL6IP1,MDFIC,CHTOP,F2R,SOCS5,ADCY7,SP3,SGCE,CYTH1,NEK7,LDB1,SEPT8,WIPF1,OGDH,AZI2,SEPT7,PICALM,FAS,CAND1,TAB2,WNT5B,STAT1,CNOT6,DUSP11,YWHAZ,MRFAP1L1,YY1,FUBP1 |
| 9.582e-03 | -4.65 | GSE17721_CPG_VS_GARDIQUIMOD_24H_BMDC_UP | MSigDB lists | GSE17721_CPG_VS_GARDIQUIMOD_24H_BMDC_UP | 189 | 41 | 17377 | 2626 |
UNK,PARP12,MECP2,C19orf25,TKT,LANCL1,UBQLN2,EIF1B,COPG2,PARK7,REPS1,NDUFS7,SPAG5,SRXN1,CAPN2,CCNA2,GATC,ATP6V0A2,ARHGEF2,SUCLG2,TIPARP,OGG1,PHKG2,DRAM2,CFL1,NUDC,BAK1,CCT2,RBM42,HARS,ADRB2,RFC2,RPS9,DHX15,RXRB,SUGP1,OSBPL11,CAPN7,ATF6,KLHDC4,CDKN2A |
| 9.582e-03 | -4.65 | GSE17721_LPS_VS_POLYIC_24H_BMDC_DN | MSigDB lists | GSE17721_LPS_VS_POLYIC_24H_BMDC_DN | 189 | 41 | 17377 | 2626 |
FEZ2,TMEM184B,CDT1,PTTG1,LAMTOR3,MYO9B,ATP6V1B2,C19orf48,SUB1,HDAC7,MTA1,TIMELESS,TTC3,AHCYL1,CTDSP2,PACS2,ZNF524,CYTH1,RB1CC1,ERLIN1,RPL38,WIPF1,RRM2,SEPT8,PFKFB3,EMP3,MTMR6,RFC2,NEU1,GIGYF1,SH3GLB1,KIF2A,HHEX,TXNDC16,BRWD1,CSK,RBMS1,KLHDC4,EHD4,NUMB,ADAM23 |
| 9.582e-03 | -4.65 | GSE42021_CD24HI_VS_CD24LOW_TCONV_THYMUS_UP | MSigDB lists | GSE42021_CD24HI_VS_CD24LOW_TCONV_THYMUS_UP | 189 | 41 | 17377 | 2626 |
H2AFZ,ANXA6,HJURP,KIAA0232,CERK,PLXNA1,CCNB1,PPP1R16B,PIP4K2A,EXT2,PDXDC1,SAC3D1,BCAT2,EBP,ANKRD28,CAPN2,INPP5A,FBXW2,CYB5R1,APOOL,AHCYL1,TPCN1,FAM171A1,TRIM14,GM2A,PDLIM2,PLK1,MYBL2,USP22,ESYT1,ARPC1A,AMZ2,CSK,APPL2,E2F1,MEGF9,ATP6V0C,PLOD3,CCNB2,CHPT1,USP13 |
| 9.582e-03 | -4.65 | GSE24634_NAIVE_CD4_TCELL_VS_DAY7_IL4_CONV_TREG_UP | MSigDB lists | GSE24634_NAIVE_CD4_TCELL_VS_DAY7_IL4_CONV_TREG_UP | 189 | 41 | 17377 | 2626 |
IER2,C9orf78,SH2D3A,KLHL21,FAM53C,CAST,ANK3,MED13L,KLF13,CDIPT,LRRC14,MOAP1,PRDM4,TPST1,JOSD1,TTC3,PIK3IP1,TP53BP2,PLCL2,SPSB3,CGGBP1,MOB4,LARS,TNFAIP3,ATG9A,COQ10B,DIDO1,CYFIP2,RHOT2,SPPL2B,SGSH,GADD45B,BBX,PQBP1,RNF38,DDX5,BRD9,TOB1,LONP2,RNF139,C7orf26 |
| 9.582e-03 | -4.65 | GSE45881_CXCR6HI_VS_CXCR1LO_COLONIC_LAMINA_PROPRIA_DN | MSigDB lists | GSE45881_CXCR6HI_VS_CXCR1LO_COLONIC_LAMINA_PROPRIA_DN | 189 | 41 | 17377 | 2626 |
PDAP1,TOR3A,TCF3,SLC2A1,SNX15,TRAK1,RPL15,NENF,GGA2,LRRC14,PTPN2,SNRNP25,TBC1D22A,AHCY,MRPL40,CNPY3,GM2A,POU2AF1,VOPP1,TELO2,ORAI2,HEMK1,AKT2,HNRNPF,ATP6V0A1,GLO1,TFEB,SH3BP5,TPD52L2,GNA12,DDOST,NIP7,HNRNPR,CSNK1G1,FAM3C,DBI,OAZ2,QRSL1,UQCRH,COPS6,USP13 |
| 9.582e-03 | -4.65 | GSE17186_NAIVE_VS_CD21HIGH_TRANSITIONAL_BCELL_DN | MSigDB lists | GSE17186_NAIVE_VS_CD21HIGH_TRANSITIONAL_BCELL_DN | 189 | 41 | 17377 | 2626 |
RAB14,PTMS,H2AFZ,LUZP1,TOR3A,CENPF,TAF6L,PMF1,OAT,SYNRG,COPG2,SPAG5,FANCL,ASAP2,LPIN2,YIF1B,KIF22,PDIA6,LPCAT1,DNMT1,ARL5A,TMBIM1,IMPA2,SOCS5,LARS,TRAPPC9,TCTEX1D2,GALC,TSPAN31,E2F3,CCDC34,WBP1,TRAM2,ATAD2,SERF2,PALB2,RBM47,MAGT1,HIPK2,PPP1R11,RAD51D |
| 9.582e-03 | -4.65 | GSE17721_0.5H_VS_12H_GARDIQUIMOD_BMDC_UP | MSigDB lists | GSE17721_0.5H_VS_12H_GARDIQUIMOD_BMDC_UP | 189 | 41 | 17377 | 2626 |
RECQL,NSMCE4A,DNAJC5,EWSR1,MUT,KIAA0100,RPS6KA1,HEXB,CERK,CTCF,GLUD1,FOXO3,GTF2F1,FANCL,RAP1A,FBXL6,DNAJC8,DAD1,BANF1,FAM89B,H2AFY,SEPT11,MRPL48,LPCAT1,MTX2,GM2A,NIPSNAP1,GPX4,CSNK1G2,AGGF1,DRAP1,OAF,POLR3GL,BRMS1,NFIL3,CDCA5,PRMT7,SIL1,IDH3B,DDB1,ATMIN |
| 9.582e-03 | -4.65 | GSE24102_GRANULOCYSTIC_MDSC_VS_NEUTROPHIL_DN | MSigDB lists | GSE24102_GRANULOCYSTIC_MDSC_VS_NEUTROPHIL_DN | 189 | 41 | 17377 | 2626 |
SRM,ST13,MRPL39,B4GALT5,RHOC,ANKH,ADO,ZFYVE21,SRXN1,TMCC3,CAPN2,ATP2A2,POP7,EXOSC1,YIF1B,MDFIC,PTGES3,TTLL12,PDIA6,GTF2H2,NOL12,SNX8,TXNL1,FYTTD1,B3GALT6,CYFIP1,PPIE,SUMF2,LUC7L,TRIM28,TSR2,EIF3G,TARS,DNAJC10,TMEM41A,HSPBP1,TBL3,DBI,SPRYD4,RRS1,CHID1 |
| 9.582e-03 | -4.65 | GSE24210_CTRL_VS_IL35_TREATED_TCONV_CD4_TCELL_UP | MSigDB lists | GSE24210_CTRL_VS_IL35_TREATED_TCONV_CD4_TCELL_UP | 189 | 41 | 17377 | 2626 |
SYS1,GMFG,CKLF,SF3B1,TRIM11,MED13L,CREBL2,TOP2B,CDC42SE2,NOTCH2,CCNL2,CRLF3,PTEN,WDR44,RCSD1,TPST1,CDKN1B,CDC25B,CNOT6L,GPD1L,MORC3,PHF20L1,CYTH1,SNX2,PPP1R21,OXR1,ARHGDIB,MCL1,RAB3IP,KDM3A,POLG2,PSMB9,SLC50A1,JAK1,BBX,CAMKMT,ARAP1,DUSP11,ROCK1,TRAF5,RNF139 |
| 9.584e-03 | -4.65 | ligase activity | molecular function | GO:0016874 | 159 | 36 | 17224 | 2647 |
NADSYN1,KARS,GCLM,PPCS,SUCLG1,MRPL39,MCCC1,FARSA,MDM2,GART,GATC,IARS,UBA5,RTCB,CTPS1,SUCLG2,SLC27A4,CARS2,ACSL5,LARS,ATP5IF1,HARS,AACS,ACSL3,POLG2,TARS,ADSS,EPRS,TTLL4,QARS,IARS2,ACAT1,QRSL1,XRCC4,ACSF2,RNF139 |
| 9.591e-03 | -4.65 | GSE40068_BCL6_POS_VS_NEG_CXCR5_POS_TFH_DN | MSigDB lists | GSE40068_BCL6_POS_VS_NEG_CXCR5_POS_TFH_DN | 178 | 39 | 17377 | 2626 |
TCF12,ATXN3,RPLP2,PHF23,TRIO,KLF13,CREBL2,TOP2B,SNN,RAPGEF6,FAM8A1,JMY,EEF2K,CTSS,THADA,PHF14,CDKN1B,TTC3,ZRANB1,MGAT5,NCOA2,WDR41,PBXIP1,BTG2,ACSL3,MAP4K4,RPL38,ITM2A,RAB3IP,MCFD2,SH3BP5,KPNA4,PPP2R5A,CERS6,RPS14,USP32,RPLP1,DCAF11,ATE1 |
| 9.591e-03 | -4.65 | GSE3982_MAST_CELL_VS_DC_UP | MSigDB lists | GSE3982_MAST_CELL_VS_DC_UP | 178 | 39 | 17377 | 2626 |
RMND5A,ANKRD27,PRKCSH,MAGED1,TRIO,MON1B,ENSA,PLAGL2,CTCF,ARF1,SNRPD3,CUTC,HMG20A,PNO1,ANKRD28,DST,NDUFB4,INPP5A,KIF13B,BRD7,TFG,STAT3,FAM171A1,CFL1,ABCC1,LARS,RHOBTB3,COQ10B,CIRBP,RPL6,PKMYT1,ESYT1,MAK16,ARHGAP15,GLOD4,RPL36,NSA2,RPLP1,USP11 |
| 9.592e-03 | -4.65 | methyl-CpG binding | molecular function | GO:0008327 | 21 | 8 | 17224 | 2647 |
MBD1,ERH,ZBTB21,MBD2,MECP2,CHTOP,MBD3,DNMT1 |
| 9.602e-03 | -4.65 | positive regulation of protein metabolic process | biological process | GO:0051247 | 1637 | 282 | 17256 | 2622 |
TXN,MAP3K7CL,XIAP,YTHDF3,CCNL2,CCNB1,UBE2I,PPP1R16B,PARK7,FBXO22,CALM2,CDK5,FIZ1,FNIP2,CDC25B,TIPARP,DNMT1,SENP1,MLST8,BAK1,PLK3,AKT2,MRNIP,TOPORS,DCUN1D5,MAP3K4,BRMS1,RPS27A,AXIN1,OGT,ARRB2,OAZ1,HDAC2,SVIP,HSPH1,CLSPN,GGA1,PHF23,GADD45G,PRKAA1,DHX9,CYCS,EIF2AK4,NOTCH2,PSEN1,METTL3,WDR48,CFLAR,DDRGK1,TFAP4,FKBP1A,DAPK1,MYDGF,GNAI2,LPCAT1,PABPC1,NSUN4,SOCS5,EIF5A,MAPKAPK3,RB1CC1,ADRB2,PTTG1IP,FXR1,CYFIP2,MAP2K2,FAS,XRCC5,DERL1,HSPBP1,FNTA,GOLGA2,NSF,CSK,CEBPG,MAP3K5,RNF14,RNF139,ALS2,KARS,ATXN3,RAF1,EIF3D,MAGED1,RAC1,TPX2,MYH9,CREBL2,DAZAP2,PRKACA,APP,ANKIB1,TERF2IP,CRKL,SHC1,RALB,MTA1,ADCY9,MRPS27,CDKN1B,RNF19A,MAVS,CLN6,ADCY7,ANKLE2,PSRC1,CDC123,KAT7,TAOK1,MAP4K4,CIRBP,CUL3,POLR2D,WBP2,CDCA2,RAB1A,SERP1,PPP2CA,PPP2R5A,HIPK2,RPLP1,TICAM1,TRIM32,LRP8,CSNK1D,USP13,RPS2,ZFP91,MECP2,HABP4,FLOT1,MAD2L2,WWP2,CCNK,PDCD10,PTEN,PTPN11,AXIN2,MAP3K14,PDPK1,KAT2A,LONRF3,TNFAIP3,JTB,MARK2,PICALM,FADD,KEAP1,OAZ2,PML,PSAP,CD81,DDB1,CCNC,KMT2E,PPP1R15B,FAM129A,CSNK2A1,NENF,SIRT2,UBQLN2,S1PR2,MAPK14,BIRC2,FANCI,PRNP,RAP1A,EIF4A3,IL6ST,MTPN,PLK1,COPS8,RBX1,NCK1,EZR,UBE2V1,CDC6,BRCA1,SOX4,PAF1,SOCS4,ADAM9,CAB39,STK11,CHEK2,DVL1,CLU,PSMC1,PPP1R12A,GORASP1,PHB2,NKD2,LAMTOR3,CIB1,RHBDD1,APOPT1,DTL,CTR9,RBM3,MDFIC,BCL2,ATP5IF1,LDB1,GBA,RTF1,MAP4K3,KRAS,PSMC4,NSMF,RUVBL2,EHD4,RNF114,IFI27L1,TRAF7,SUMO2,DUSP22,LYN,BCAP31,PAIP1,USP5,RAD23A,MDM2,KIF14,PIN1,AKAP8,PDCD2,CHTOP,F2R,ABI1,DVL2,HTRA2,CHP1,TIMP2,POLR2G,BIRC3,RAB7A,EDEM2,TOLLIP,PEF1,RPS9,IDE,TAB2,SCAP,TIMM17A,ARNTL,GADD45B,PLGRKT,MAPK1,SMURF1,SMAD4,MIF,DAP,PAWR,DCUN1D4,CSNK1A1,FBXO5,FASTKD3,IRF4,FGFR3,TANK,BRD7,ARHGEF2,ATG13,STAT3,TGFB1,TELO2,COA3,RHOA,ADAM17,PRKAR1B,SYMPK,HSPA1B,MAPK3,CNOT9,NEK1,PDCD6,TWSG1,OSBPL8,PKD2,UBE2C,HRAS,IFI16 |
| 9.606e-03 | -4.65 | DAPK3 (death associated protein kinase 3) | protein interactions | 1613 | 45 | 14 | 17029 | 2761 |
UBE2D3,CEP104,MDM2,PCM1,AATF,GPS2,MYO18A,MYH9,PAWR,CHEK2,CAPZA2,CDK2,DAPK3,MEAF6 |
| 9.606e-03 | -4.65 | BHLHA15 (basic helix-loop-helix family member a15) | protein interactions | 168620 | 45 | 14 | 17029 | 2761 |
NOL12,RPS15,PHF10,RBM23,DAP3,ZCCHC9,PARP12,RPS27A,ZFP91,TCF3,CHCHD2,YBX1,FAF1,DHX57 |
| 9.606e-03 | -4.65 | CHMP5 (charged multivesicular body protein 5) | protein interactions | 51510 | 45 | 14 | 17029 | 2761 |
CHMP2A,UNK,PDCD10,CHMP4A,EWSR1,RAB7A,HABP4,RPL38,SMARCA4,CHMP4B,GTF3A,VPS4A,TFG,ISG15 |
| 9.606e-03 | -4.65 | TWIST1 (twist family bHLH transcription factor 1) | protein interactions | 7291 | 45 | 14 | 17029 | 2761 |
PPP2CA,MAX,ETS2,CHD3,KMT5A,MTA2,NEIL3,TCF3,BRAP,KRAS,YY1,WDR5,STAT3,HDAC2 |
| 9.606e-03 | -4.65 | TNKS1BP1 (tankyrase 1 binding protein 1) | protein interactions | 85456 | 45 | 14 | 17029 | 2761 |
GADD45B,CSNK2A1,XRCC3,CNOT6,CAPZA2,CNOT6L,MCM2,CNOT11,RAB11A,TOB1,CCAR1,IFI16,CDC5L,CBX3 |
| 9.606e-03 | -4.65 | NUP43 (nucleoporin 43) | protein interactions | 348995 | 45 | 14 | 17029 | 2761 |
KIF5B,TP53RK,DCTN2,XPA,NUP107,LAGE3,NUP153,NUP85,CCT8,SENP1,ISG15,SEH1L,IFI16,DDB1 |
| 9.626e-03 | -4.64 | Endometrial cancer | KEGG pathways | hsa05213 | 50 | 15 | 7161 | 1149 |
PDPK1,NRAS,PTEN,RAF1,AXIN1,AKT2,PIK3R2,AXIN2,KRAS,ELK1,MAPK1,HRAS,MAP2K2,FOXO3,MAPK3 |
| 9.626e-03 | -4.64 | Endometrial cancer | KEGG pathways | ko05213 | 50 | 15 | 7161 | 1149 |
PDPK1,NRAS,PTEN,RAF1,AXIN1,AKT2,PIK3R2,AXIN2,KRAS,ELK1,MAPK1,HRAS,MAP2K2,FOXO3,MAPK3 |
| 9.633e-03 | -4.64 | FGB (fibrinogen beta chain) | protein interactions | 2244 | 111 | 28 | 17029 | 2761 |
SNX27,USO1,TK1,RPRD1A,RHOA,PBK,ARMT1,ADSL,EIF2A,HDGFL2,SPR,PMVK,MIS12,UBLCP1,PAPOLA,GTF2F1,MCTS1,KIF2A,CTNNBL1,DUSP3,ATG3,MAPK6,PTPN11,NAA50,CAB39,TCEA1,ASB6,RPRD1B |
| 9.637e-03 | -4.64 | COMM_domain | pfam domains | PF07258 | 10 | 5 | 17054 | 2545 |
COMMD10,COMMD5,COMMD4,COMMD6,COMMD8 |
| 9.639e-03 | -4.64 | REACTOME_DIABETES_PATHWAYS | MSigDB lists | REACTOME_DIABETES_PATHWAYS | 124 | 29 | 17377 | 2626 |
EXOC3,EXOSC6,ADD1,CXXC1,EXOSC9,SYVN1,PARN,SERP1,LMNA,DNAJB9,SSR1,YIF1A,SEC31A,KIF5B,SEC11A,EXOSC7,SHC1,TATDN2,EXOSC1,EXOC4,KHSRP,ATF6,SPCS3,PDIA6,ATP6V0D1,CTDSP2,MYO5A,PREB,DCTN1 |
| 9.695e-03 | -4.64 | Anapc13 (anaphase promoting complex subunit 13) | protein interactions | 69010 | 28 | 10 | 17029 | 2761 |
FYTTD1,CDC16,CDC27,ANAPC7,DMWD,CDC23,USP11,KIF11,ZC3H3,ANAPC4 |
| 9.695e-03 | -4.64 | CEBPD (CCAAT enhancer binding protein delta) | protein interactions | 1052 | 28 | 10 | 17029 | 2761 |
RB1,TRIM26,SIAH2,CEBPG,E2F1,UBE2I,BLM,SMAD4,SPAG5,IPO4 |
| 9.695e-03 | -4.64 | AKR7A2 (aldo-keto reductase family 7 member A2) | protein interactions | 8574 | 28 | 10 | 17029 | 2761 |
PCNA,TXN,CTR9,MTMR12,CCNB1,CDK2,MCPH1,PSMC1,EYA2,MSH6 |
| 9.695e-03 | -4.64 | METTL13 (methyltransferase like 13) | protein interactions | 51603 | 28 | 10 | 17029 | 2761 |
PTPN2,DNAJC8,SYNCRIP,TBC1D22A,HLA-E,CUL3,KIF11,PFKP,SNRPA,FAS |
| 9.695e-03 | -4.64 | Itga5 (integrin alpha 5 (fibronectin receptor alpha)) | protein interactions | 16402 | 28 | 10 | 17029 | 2761 |
LUZP1,ARPC5,ACTR3,MYO18A,ITGB1,OGT,AP2B1,DAPK3,MYO5A,MICAL3 |
| 9.695e-03 | -4.64 | NOL8 (nucleolar protein 8) | protein interactions | 55035 | 28 | 10 | 17029 | 2761 |
DDX47,NIP7,URB2,ZNF512,GOPC,MECP2,NOL8,RRAGC,KRAS,FBL |
| 9.695e-03 | -4.64 | PTCD1 (pentatricopeptide repeat domain 1) | protein interactions | 26024 | 28 | 10 | 17029 | 2761 |
MRPL50,DDX28,RBM42,MRPL39,RBMX,RPL6,ILF3,RBM3,MCM2,ZC3H3 |
| 9.695e-03 | -4.64 | KLF4 (Kruppel like factor 4) | protein interactions | 9314 | 28 | 10 | 17029 | 2761 |
HUWE1,HDAC7,VHL,SMARCA4,CUL1,ELK1,KLF6,APP,FBXO22,HDAC2 |
| 9.695e-03 | -4.64 | SCMH1 (Scm polycomb group protein homolog 1) | protein interactions | 22955 | 28 | 10 | 17029 | 2761 |
PHC2,MOB4,UBQLN4,LZTR1,EWSR1,CDC42,TOB1,GNB2,CBX4,LYPLA2 |
| 9.695e-03 | -4.64 | ABCB7 (ATP binding cassette subfamily B member 7) | protein interactions | 22 | 28 | 10 | 17029 | 2761 |
EPRS,RPN1,UNK,PDCD6,ATP6V1D,NDUFB6,ACAT1,NDUFA4,APP,MAT2A |
| 9.695e-03 | -4.64 | MTDH (metadherin) | protein interactions | 92140 | 28 | 10 | 17029 | 2761 |
CUL3,TMEM216,CSNK2A1,TOPORS,TARDBP,SIRT2,SND1,PLEC,SNN,LMNA |
| 9.695e-03 | -4.64 | TAF3 (TATA-box binding protein associated factor 3) | protein interactions | 83860 | 28 | 10 | 17029 | 2761 |
SAP130,MZT1,CDC16,KAT2A,CTCF,KPNA2,NAP1L4,TAF12,CDC23,TAF6 |
| 9.729e-03 | -4.63 | CHD4 (chromodomain helicase DNA binding protein 4) | protein interactions | 1108 | 136 | 33 | 17029 | 2761 |
PHF20L1,ZNF524,BRD4,MTA2,SUZ12,SUMO2,CSNK2A1,SMARCA4,NFATC2,UBE2I,MBD3,PARK7,USP36,PHF6,RPA1,CBX3,RPA2,UBTF,SUB1,CHD3,MTA1,BANF1,PML,RBPJ,RUVBL2,H3F3A,RBBP4,EIF5,MCPH1,SMARCE1,DNMT1,HDAC2,SAP30 |
| 9.730e-03 | -4.63 | ELAC2 (elaC ribonuclease Z 2) | protein interactions | 60528 | 54 | 16 | 17029 | 2761 |
HARS,HNRNPF,GORASP2,KIF2C,NDUFA7,GOLM1,C12orf10,SMAD2,ATIC,WDR4,EIF2D,DNAJC17,TNPO3,DDX5,MRPL21,PFKP |
| 9.730e-03 | -4.63 | BORCS6 (BLOC-1 related complex subunit 6) | protein interactions | 54785 | 54 | 16 | 17029 | 2761 |
CCDC57,LUZP1,SHPRH,DCTN2,LAMTOR3,ATP6V0A1,BICD2,KIF11,KTN1,SPAG5,CEP55,LAMTOR4,NDE1,SASS6,TACC3,SNAPIN |
| 9.730e-03 | -4.63 | DYNC1I1 (dynein cytoplasmic 1 intermediate chain 1) | protein interactions | 1780 | 54 | 16 | 17029 | 2761 |
STAU1,TK1,FAM110A,PIN1,KAT7,DYNLL1,TAOK1,DCTN2,FAM83D,CUL3,DNM2,BICD2,BECN1,ECPAS,DYNC1LI2,DCTN1 |
| 9.730e-03 | -4.63 | GTF2F2 (general transcription factor IIF subunit 2) | protein interactions | 2963 | 54 | 16 | 17029 | 2761 |
CTDP1,EWSR1,POLR2G,TCTEX1D2,RPL27A,SRRT,LMNA,POLR2A,GTF2F1,TRAM2,POLR2J,EFTUD2,CEBPG,TCEA1,CREB1,ATF2 |
| 9.730e-03 | -4.63 | TP53RK (TP53 regulating kinase) | protein interactions | 112858 | 54 | 16 | 17029 | 2761 |
METTL1,COMMD10,MBIP,TPD52L2,MDM2,ACTR3,UBA5,WDR4,NSUN2,LAGE3,RANGAP1,EFL1,GLRX3,COMMD4,RPRD1B,EEF2K |
| 9.730e-03 | -4.63 | TWF1 (twinfilin actin binding protein 1) | protein interactions | 5756 | 54 | 16 | 17029 | 2761 |
KIF5B,TIGAR,UBXN1,MYO18A,DAPK1,TPX2,BCL7C,HNRNPF,MYH9,ADSL,CAPZA2,ANLN,APP,USP5,CDC5L,MCTS1 |
| 9.765e-03 | -4.63 | MIT | interpro domains | IPR007330 | 10 | 5 | 18492 | 2768 |
ULK3,VPS4A,RPS6KC1,SNX15,CAPN7 |
| 9.765e-03 | -4.63 | COMM | interpro domains | IPR017920 | 10 | 5 | 18492 | 2768 |
COMMD10,COMMD5,COMMD4,COMMD6,COMMD8 |
| 9.786e-03 | -4.63 | IREB2 (iron responsive element binding protein 2) | protein interactions | 3658 | 24 | 9 | 17029 | 2761 |
ALDH3B1,VHL,CAMKMT,ENSA,YBX1,KRAS,CCNL2,APP,USP53 |
| 9.786e-03 | -4.63 | PDXK (pyridoxal kinase) | protein interactions | 8566 | 24 | 9 | 17029 | 2761 |
SNX2,CUL3,OGT,RABIF,CUL1,EZR,MDH1,OAT,CAND1 |
| 9.786e-03 | -4.63 | TEX28 (testis expressed 28) | protein interactions | 1527 | 24 | 9 | 17029 | 2761 |
KIAA0100,FBXO28,KIF14,STX18,UPK3BL1,SARAF,PDE3B,TMEM201,TMCC3 |
| 9.786e-03 | -4.63 | KIAA1191 (KIAA1191) | protein interactions | 57179 | 24 | 9 | 17029 | 2761 |
TERF2IP,NOL12,HUWE1,APP,NUP58,POT1,CARM1,MSH6,PRNP |
| 9.786e-03 | -4.63 | NR1H4 (nuclear receptor subfamily 1 group H member 4) | protein interactions | 9971 | 24 | 9 | 17029 | 2761 |
NCOR2,GPS2,PRKDC,RRM2,NCOA1,CARM1,RXRB,SMARCD1,XRCC5 |
| 9.786e-03 | -4.63 | CCDC74B (coiled-coil domain containing 74B) | protein interactions | 91409 | 24 | 9 | 17029 | 2761 |
PSMD2,PSMD1,UCHL5,PSMD8,PSMD3,THNSL1,PSMC1,BTBD1,PSMC4 |
| 9.786e-03 | -4.63 | CAMSAP1 (calmodulin regulated spectrin associated protein 1) | protein interactions | 157922 | 24 | 9 | 17029 | 2761 |
CEP104,PCM1,CENPJ,POC1A,ODF2,RBPJ,SMAD1,SRPK2,DCTN1 |
| 9.786e-03 | -4.63 | COX17 (COX17, cytochrome c oxidase copper chaperone) | protein interactions | 10063 | 24 | 9 | 17029 | 2761 |
MIF,UFC1,TKT,HADHB,TALDO1,COPS6,SPR,SCYL2,CFL1 |
| 9.786e-03 | -4.63 | LAMTOR2 (late endosomal/lysosomal adaptor, MAPK and MTOR activator 2) | protein interactions | 28956 | 24 | 9 | 17029 | 2761 |
RRAGC,SDHB,ABCB10,ATP6V1B2,ATP6V0D1,LAMTOR4,ILF3,LAMTOR3,FLOT1 |
| 9.786e-03 | -4.63 | PSMG4 (proteasome assembly chaperone 4) | protein interactions | 389362 | 24 | 9 | 17029 | 2761 |
TRIM41,WDR1,CCDC69,PSMA1,GLO1,NIT2,TALDO1,PSMB9,PSMB3 |
| 9.786e-03 | -4.63 | RIDA (reactive intermediate imine deaminase A homolog) | protein interactions | 10247 | 24 | 9 | 17029 | 2761 |
SUGP1,DEAF1,MDM2,SEPT9,ACOX1,PQBP1,RBMS1,NDUFA7,CARM1 |
| 9.786e-03 | -4.63 | HMGN2 (high mobility group nucleosomal binding domain 2) | protein interactions | 3151 | 24 | 9 | 17029 | 2761 |
HMGN1,H2AFY,KRAS,UBE2I,PRKACA,CDK2,SRPK2,HMGN2,TERF2 |
| 9.786e-03 | -4.63 | Wiz (widely-interspaced zinc finger motifs) | protein interactions | 22404 | 24 | 9 | 17029 | 2761 |
MKNK1,GOLGA4,MIER1,EHMT1,MIER2,PRPSAP1,SDE2,CLNS1A,HDAC2 |
| 9.786e-03 | -4.63 | DOCK1 (dedicator of cytokinesis 1) | protein interactions | 1793 | 24 | 9 | 17029 | 2761 |
CRKL,WASF2,RHOG,ELMO1,RAC1,CUL1,JMJD6,MAP1LC3B,PRKACA |
| 9.786e-03 | -4.63 | M6PR (mannose-6-phosphate receptor, cation dependent) | protein interactions | 4074 | 24 | 9 | 17029 | 2761 |
PON2,ACP2,NDUFB4,HPDL,GGA1,ACOX1,RPL6,GGA2,NDUFS4 |
| 9.794e-03 | -4.63 | ovary-carcinoma-endometrioid_carcinoma | COSMIC cancer mutations | ovary-carcinoma-endometrioid_carcinoma | 466 | 88 | 17385 | 2587 |
TP53RK,DNMT3A,TSC2,NF1,RPS6KA1,RAF1,CSNK2A1,SMARCA4,PRKACA,TWF2,LYN,MAPK14,EEF2K,CDK5,ABL2,PDK2,PRKD3,NEK6,SCYL3,CDK12,SRPK2,PLK1,PLK3,NRAS,BRD4,AKT2,VHL,PBK,TLK1,MAP4K4,PKMYT1,BRCA1,AURKB,STK17B,TRIM28,MAP3K4,JAK1,CLK3,STK38,HIPK2,AXIN1,LIMK1,FASTK,STK11,RNASEL,CHEK2,MAPK1,SMAD4,PRPF4B,SCYL1,TRIO,PRKAA1,CDK13,ADCK5,EIF2AK4,CSNK1A1,SCYL2,FGFR3,RB1,PTEN,MSH2,DAPK1,PTPN11,PHKG2,CAMK2G,CSNK1G3,MSH6,PDPK1,CSNK1G2,NEK7,EIF2AK1,MAP4K3,KRAS,ARID1A,MARK2,MAP2K2,DAPK3,MAPK3,MASTL,GNAS,MAPK6,MAP3K5,CDK2,RPS6KC1,HIPK3,HRAS,NRBP1,CDKN2A |
| 9.812e-03 | -4.62 | DYRK1A (dual specificity tyrosine phosphorylation regulated kinase 1A) | protein interactions | 1859 | 82 | 22 | 17029 | 2761 |
FAM53C,SF3B1,DYNLL1,KIAA0232,BRCA1,CCNL2,SRSF5,PRKACA,APP,ISG15,SRSF1,RB1,TSC1,CCNA2,FNTA,RBL1,HIPK2,SRSF4,CREB1,MAP3K5,GLCCI1,RNF169 |
| 9.816e-03 | -4.62 | endoplasmic reticulum unfolded protein response | biological process | GO:0030968 | 113 | 27 | 17256 | 2622 |
BAK1,SEC61B,ADD1,SEC61G,CXXC1,ERO1A,SYVN1,EDEM2,SERP1,DNAJB9,LMNA,SSR1,DERL1,SEC31A,YIF1A,RNF121,SEC61A1,SHC1,TATDN2,ASNA1,ATF6,MYDGF,PDIA6,CTDSP2,ATP6V0D1,PREB,DCTN1 |
| 9.816e-03 | -4.62 | internal protein amino acid acetylation | biological process | GO:0006475 | 113 | 27 | 17256 | 2622 |
KAT2A,KAT7,MECP2,MDH2,LDB1,ELP4,TAF6L,USP22,WDR5,SUPT7L,MBD3,MEAF6,IRF4,MBIP,BRPF3,TEX30,OGT,NAA50,KANSL2,TAF5L,RUVBL2,BEND3,NCOA1,TAF12,ATF2,NAA60,SGF29 |
| 9.822e-03 | -4.62 | Hepatitis C and Hepatocellular Carcinoma | WikiPathways | WP3646 | 51 | 15 | 5312 | 837 |
TGFB1,BIRC3,JAK1,BIRC5,RAC1,VAV2,PTPN11,RRM2,BCL2L1,BRCA1,STAT3,E2F2,MAPK14,SMAD4,MAPK3 |
| 9.842e-03 | -4.62 | GSE10147_IL3_VS_IL3_AND_HIVP17_STIM_PDC_UP | MSigDB lists | GSE10147_IL3_VS_IL3_AND_HIVP17_STIM_PDC_UP | 151 | 34 | 17377 | 2626 |
SCAMP3,CXXC1,HABP4,WDTC1,FAM76A,CREBL2,BLM,RB1,CLUAP1,CRAT,AP1M1,TTC17,UBE3C,PPP6R1,TPCN1,NIPSNAP1,TDP1,ZMYND11,KAT7,DIDO1,USP21,UPF1,OSBPL11,CSK,CSNK1G1,PTAR1,IARS2,USP32,ACBD4,DDX5,WDR76,PSAP,TFDP2,PFKP |
| 9.871e-03 | -4.62 | GO_NEGATIVE_REGULATION_OF_CELL_DEATH | MSigDB lists | GO_NEGATIVE_REGULATION_OF_CELL_DEATH | 837 | 151 | 17377 | 2626 |
TXN,TSC22D3,TMEM109,XIAP,CSNK2A1,SIRT2,BECN1,MIEN1,BIRC2,PARK7,PRNP,EEF2K,CDK5,PA2G4,IL6ST,XRCC2,NOC2L,OGG1,PLK3,PLK1,PGAP2,AATF,NCK1,AKT2,VHL,MCL1,TOPORS,AURKB,BRCA1,SOX4,SLC25A5,ARF4,KRIT1,RAD18,RPS27A,PRDX5,MYO18A,ITGB1,OGT,ZNF268,CLU,ROCK1,CLN3,ARRB2,PSMC1,PDCD4,HDAC2,HSPH1,DNAJC5,PHB2,NACA,PRKAA1,CIB1,NOTCH2,PSEN1,RHBDD1,LMNA,CFLAR,CD59,HDAC7,DAD1,DAPK1,ARL6IP1,MSH2,KIFAP3,BCL2,RB1CC1,ZMYND11,OXR1,KRAS,SYVN1,PTTG1IP,FAS,CAT,PALB2,SIAH2,NUP62,CABIN1,YWHAZ,GPI,ZNF830,BTBD10,ADNP2,CHMP2A,IVNS1ABP,RAF1,RPS6KA1,CAST,BCL2L1,RRN3,MDM2,TNFAIP8,KIF14,PIN1,CDKN1B,PARL,CORO1A,F2R,NAA35,TMBIM1,HTRA2,CFL1,PPIF,BIRC3,PPT1,BTG2,MAP4K4,VDAC2,HTATIP2,GLO1,DNAJA1,CHMP4A,HIPK2,CHMP4B,TRIM32,PPP5C,SMAD4,CBX4,ZC3HC1,MIF,BCL2L12,GCLM,TMBIM4,MECP2,SRSF6,EYA1,PDCD10,KLHL20,PTEN,ARHGEF2,ANXA5,CREB1,CITED2,STAT3,PDPK1,HMGN5,TNFAIP3,PRKDC,RFFL,API5,FADD,HSPA1B,PRDX3,BIRC5,HMGB2,PSAP,IGBP1,HRAS,HIPK3,DDB1,HIGD2A |
| 9.904e-03 | -4.61 | HALLMARK_ANDROGEN_RESPONSE | MSigDB lists | HALLMARK_ANDROGEN_RESPONSE | 98 | 24 | 17377 | 2626 |
ELOVL5,ABHD2,ZBTB10,ELL2,ANKH,ACSL3,B4GALT1,UBE2I,DNAJB9,XRCC5,HERC3,PA2G4,UAP1,TNFAIP8,RAB4A,DBI,FKBP5,SLC26A2,SPCS3,LMAN1,ZMIZ1,GPD1L,PDLIM5,NGLY1 |
| 9.934e-03 | -4.61 | CREIGHTON_ENDOCRINE_THERAPY_RESISTANCE_5 | MSigDB lists | CREIGHTON_ENDOCRINE_THERAPY_RESISTANCE_5 | 424 | 82 | 17377 | 2626 |
IER2,NF1,TMEM41B,FAM129A,ANK3,MYH9,TBC1D13,SLC20A1,CPNE3,PAIP1,RNF103,ZNF275,PRNP,APLP2,LPIN2,SOCS6,RNF19A,ABCC5,ATP6V1G1,VPS13B,TIMP2,MIOS,GMFB,EZR,GALNT7,DIDO1,RAB1A,RAB22A,PLEKHF2,ARF4,TRAM2,TMEM41A,BRWD1,MAFK,SEL1L,ADAM9,CAB39,GALNT10,NCOA1,PDXK,TRAF5,GLCCI1,DCAF5,NXT2,WSB2,GORASP1,CERK,TRAK1,ASAH1,MEF2A,DOCK11,PSEN1,RAB11A,COPB2,INPP5A,KIF13B,GLTP,SLC12A2,NIPAL3,PHF20L1,RHOA,TRAFD1,ELL2,TACC1,NET1,NUDT4,AACS,PIP4K2C,HEBP2,MTMR12,KRAS,SMAP2,PDCD6,FNTA,GOLGA7,ZHX1,TWSG1,DBI,MAPK6,ZDHHC7,PKD2,CPEB2 |
| 9.943e-03 | -4.61 | Mitophagy - animal | KEGG pathways | ko04137 | 64 | 18 | 7161 | 1149 |
NRAS,ATG9A,RAB7A,CSNK2A1,KRAS,BCL2L1,RHOT1,BECN1,RHOT2,FOXO3,MFN2,TFEB,OPTN,TBC1D17,TFE3,E2F1,CITED2,HRAS |
| 9.943e-03 | -4.61 | Mitophagy - animal | KEGG pathways | hsa04137 | 64 | 18 | 7161 | 1149 |
NRAS,ATG9A,RAB7A,CSNK2A1,KRAS,BCL2L1,RHOT1,BECN1,RHOT2,FOXO3,MFN2,TFEB,OPTN,TBC1D17,TFE3,E2F1,CITED2,HRAS |
| 9.976e-03 | -4.61 | GSE13547_CTRL_VS_ANTI_IGM_STIM_ZFX_KO_BCELL_2H_DN | MSigDB lists | GSE13547_CTRL_VS_ANTI_IGM_STIM_ZFX_KO_BCELL_2H_DN | 162 | 36 | 17377 | 2626 |
EXOC3,MRPL42,CKLF,ASAH1,LANCL1,GSTK1,DDX56,CTSS,GART,EIF2S2,IARS,TNFAIP8,RBM34,ZNHIT6,RNASEH2A,FBL,GTF2H2,RFC3,GBA,BRCA1,EIF2A,PCGF1,RFC2,CLNS1A,PRIM1,XRCC5,RAD18,PDLIM1,GRIPAP1,MRPL27,PPA2,PRMT7,CBWD1,WDR76,PITRM1,DDX52 |
| 9.993e-03 | -4.61 | GSE15930_STIM_VS_STIM_AND_IL-12_48H_CD8_T_CELL_DN | MSigDB lists | GSE15930_STIM_VS_STIM_AND_IL-12_48H_CD8_T_CELL_DN | 195 | 42 | 17377 | 2626 |
CYTIP,CDS2,SCOC,CASP6,GNPDA1,TMEM41B,PTTG1,GADD45G,DBF4,FLOT1,ABCB10,SIRT2,OAT,TMEM165,NDUFS4,PRNP,ANKRD28,CSDE1,SUB1,LHX8,UBA5,CLDND1,PDIA6,ARL5A,S100A6,PTPRK,PGS1,LRBA,CPOX,LDHA,ADRB2,RHOB,DDX17,RWDD4,RBPJ,TMEM159,PGAM1,FAM208A,HRAS,ABCA1,ZMAT3,SSRP1 |
| 9.995e-03 | -4.61 | NUYTTEN_NIPP1_TARGETS_UP | MSigDB lists | NUYTTEN_NIPP1_TARGETS_UP | 698 | 128 | 17377 | 2626 |
UBE2E2,YTHDC2,TAP1,TMEM109,CDC42SE2,BIRC2,CREM,KRR1,AP3S2,RABGAP1L,JAZF1,CISD2,MOB1A,SPTSSA,OGG1,DRAM2,SEH1L,WDR41,VPS13B,FYTTD1,CCDC138,GMFB,PITPNB,DCUN1D5,LIMK1,LUC7L3,OGT,RNASEL,MRPL13,CCDC59,SMNDC1,NUMB,DDX58,ZCCHC9,PARP12,MUT,TATDN3,LAMTOR3,RGS2,ARL6IP1,GCC2,PRIM2,ELL2,ARMC8,KDM3A,ANKRD46,ISG15,ADSS,PTPRF,TSC1,GOLGA4,SYNCRIP,UAP1,RBM25,TBPL1,NUP62,YWHAZ,APOL2,ZC3HAV1,N4BP2L2,EGLN1,TCF12,REPS2,EIF3D,C5orf30,C2orf49,DAZAP2,COMMD8,IARS,SP100,SAR1A,UBA5,ZNF226,RPN2,BIRC3,FAM118B,GOPC,WIPF1,BOLA1,TANC1,HERPUD2,CDC23,AZI2,ARL5B,POLG2,GAR1,USP36,CHCHD3,TAB2,ACYP1,TIMM17A,PROSER1,STAT1,SNRPG,XRCC4,GCLM,MAGEH1,B4GALT5,HABP4,TMX3,SLC25A12,SECISBP2,ARGLU1,LANCL1,DCUN1D4,GFM2,PNO1,MAT2B,TANK,OSTC,TMX1,PHF20L1,TNFAIP3,USP42,PPP1R21,FBXO9,KLF6,TMEM127,PDCD6,HGS,MFAP1,FAM3C,PML,RBPJ,TATDN1,RPS6KC1,IFI16,ANAPC4 |
| 1.000e-02 | -4.60 | phosphoprotein phosphatase activity | molecular function | GO:0004721 | 181 | 40 | 17224 | 2647 |
CTDP1,EYA1,PTP4A3,CYCS,PPP3CB,DUSP22,UBLCP1,PTPN2,PPP1R3B,PDXP,PTEN,MTMR4,PPP4R1,PPP6C,PTPN11,CDC25B,MINPP1,ILKAP,CTDSP2,CAMK2G,TIMM50,PTPRK,PPP3CA,PTPN18,MTMR6,STYXL1,MTMR3,PPP2CA,PTPRF,PPP2R5A,DUSP3,PPM1G,PTPN7,PPP3R1,PPA2,DUSP11,PTPDC1,PPP5C,PPP2R2D,EYA2 |
| 1.001e-02 | -4.60 | soft_tissue-fibrous_tissue_and_uncertain_origin-gastrointestinal_stromal_tumour-spindle | COSMIC cancer mutations | soft_tissue-fibrous_tissue_and_uncertain_origin-gastrointestinal_stromal_tumour-spindle | 26 | 9 | 17385 | 2587 |
FGFR3,RB1,NRAS,NF1,PTEN,KRAS,HRAS,MAP2K2,CDKN2A |
| 1.001e-02 | -4.60 | soft_tissue-fat-liposarcoma | COSMIC cancer mutations | soft_tissue-fat-liposarcoma | 26 | 9 | 17385 | 2587 |
EWSR1,NRAS,NF1,SF3B1,STK11,KRAS,FUS,HRAS,CDKN2A |
| 1.001e-02 | -4.60 | soft_tissue-nerve_sheath-schwannoma | COSMIC cancer mutations | soft_tissue-nerve_sheath-schwannoma | 26 | 9 | 17385 | 2587 |
EWSR1,NF1,PTEN,ETV6,STK11,KRAS,FUS,HRAS,CDKN2A |
| 1.001e-02 | -4.60 | gastrointestinal_tract_(site_indeterminate) | COSMIC cancer mutations | gastrointestinal_tract_(site_indeterminate) | 26 | 9 | 17385 | 2587 |
GNAS,NRAS,TNFAIP3,STK11,KRAS,MEN1,STAT3,SMAD4,CDKN2A |
| 1.001e-02 | -4.60 | MODULE_430 | MSigDB lists | MODULE_430 | 53 | 15 | 17377 | 2626 |
DECR1,HDAC7,ARHGEF1,ARHGDIB,CORO1A,SYVN1,WDR76,CYFIP2,MEN1,TAZ,SPPL2B,PPP6R1,RPS9,SOCS7,HP1BP3 |
| 1.001e-02 | -4.60 | ELVIDGE_HYPOXIA_BY_DMOG_DN | MSigDB lists | ELVIDGE_HYPOXIA_BY_DMOG_DN | 53 | 15 | 17377 | 2626 |
SRM,RPP25,HSPA4,IDE,URB2,IDH3A,TOR3A,ATP6V0A2,SLC29A1,SDF2L1,CORO1A,SLC25A44,ODC1,POLR3K,SRSF1 |
| 1.002e-02 | -4.60 | response to peptide hormone | biological process | GO:0043434 | 387 | 76 | 17256 | 2622 |
MAX,SLC2A1,WDTC1,ATP6V1B2,PRKACA,LYN,GNB2,EEF2K,USF1,RAB8A,ATP6V0B,PDK2,CCNA2,MDM2,SHC1,GOT2,ADCY9,PIK3R2,SRSF4,UPRT,CDKN1B,AHCYL1,CDC5L,ADCY7,ATP6V1G1,AKT2,BTG2,GNG7,ATP6V0A1,CDC6,LRP5,SOCS7,HHEX,IDE,SCAP,OGT,STAT1,ATP6V0C,MAPK1,C2CD5,ATP6V0E1,SLC25A33,AGTRAP,SRSF6,AP3S1,ARID1B,CFLAR,PTPN2,PTEN,ATP6V0A2,CYC1,CREB1,STAT3,ATP6V0D1,MYO5A,TGFB1,PDPK1,CYFIP1,PRKDC,DENND4C,PRKAR1B,RANGAP1,SRSF5,MEN1,PKM,PDE3B,APPL1,MAPK3,CAT,TSC1,EPRS,ATP6V1D,CSK,RBBP4,ATP6V1C1,CPEB2 |
| 1.002e-02 | -4.60 | endoplasmic reticulum organization | biological process | GO:0007029 | 48 | 14 | 17256 | 2622 |
SEC31A,RAB18,TRAM2,SEC61A1,VMP1,STX18,ARL6IP1,ZFYVE27,TOR1AIP2,LMAN1,SEC16A,RTN3,WRB,TMEM33 |
| 1.004e-02 | -4.60 | IL-2 Signaling Pathway | WikiPathways | WP49 | 42 | 13 | 5312 | 837 |
CRKL,JAK1,SHC1,RAF1,PTPN11,STAT1,BCL2,STAT3,MAPK1,HRAS,MAP2K2,FOXO3,MAPK3 |
| 1.004e-02 | -4.60 | GO_POSITIVE_REGULATION_OF_I_KAPPAB_KINASE_NF_KAPPAB_SIGNALING | MSigDB lists | GO_POSITIVE_REGULATION_OF_I_KAPPAB_KINASE_NF_KAPPAB_SIGNALING | 173 | 38 | 17377 | 2626 |
MIB2,RHOC,IRF3,SLC35B2,UBE2I,SLC20A1,BIRC2,CFLAR,DDRGK1,TERF2IP,FKBP1A,C18orf32,NEK6,ZDHHC13,MAVS,MAP3K14,TFG,F2R,EEF1D,RHOA,BRD4,TRIM8,BIRC3,MIER1,ATP2C1,UBE2V1,FADD,TAB2,RPS27A,CANT1,NUP62,ZNF268,TICAM1,TMEM101,TRIM32,PPP5C,TRAF5,ZC3HAV1 |
| 1.004e-02 | -4.60 | PURBEY_TARGETS_OF_CTBP1_AND_SATB1_DN | MSigDB lists | PURBEY_TARGETS_OF_CTBP1_AND_SATB1_DN | 173 | 38 | 17377 | 2626 |
CDK2AP2,ENSA,ATP6V1B2,PMVK,EDC3,RTKN,RBM17,FARSA,RAP1A,MDM2,GATC,TIMM23,PDCD2,ZFYVE27,SCAMP4,ALDH18A1,TRIM14,MYO5A,CPNE1,PPIF,DDX28,NOL8,GBA,ATP6V0A1,CCNF,MAP2K2,PAF1,AMZ2,ZNF282,PWWP2B,PDCD6,MAP4,FN3KRP,KHSRP,ASNA1,PDXK,ZSWIM3,CDKN2A |
| 1.004e-02 | -4.60 | GSE14415_ACT_TCONV_VS_ACT_NATURAL_TREG_DN | MSigDB lists | GSE14415_ACT_TCONV_VS_ACT_NATURAL_TREG_DN | 173 | 38 | 17377 | 2626 |
CHMP2A,FAM129A,SRGN,RACGAP1,SDF2L1,REEP5,MFSD10,MXD1,DTL,HOMER1,SMC3,SNX18,KIF14,SIVA1,LPIN2,RBM3,MYO5A,ELOF1,SAP30,DDX28,ELL2,PBK,HTATIP2,CCDC34,CDC6,CDCA2,ODC1,ASF1B,HMGN2,MYO1F,ATAD2,CDC27,GADD45B,MRPL27,ADAM9,ATF6,FKBP5,AP2S1 |
| 1.004e-02 | -4.60 | GSE46606_UNSTIM_VS_CD40L_IL2_IL5_1DAY_STIMULATED_IRF4_KO_BCELL_DN | MSigDB lists | GSE46606_UNSTIM_VS_CD40L_IL2_IL5_1DAY_STIMULATED_IRF4_KO_BCELL_DN | 173 | 38 | 17377 | 2626 |
NCOR2,GLT8D1,PLXNC1,LUZP1,DCTN2,KLF13,KIF2C,RGS2,ZADH2,ZNF79,RAPGEF6,PAIP2,CREM,SAP130,RBM23,ZNF449,FBXO7,TPST1,TNPO2,ARHGEF2,JOSD1,MDFIC,CLDND1,TSHZ1,IFRD1,CYTH1,RAB3IP,FXR1,RFC2,RAB5B,RHOB,GNA12,KPNA1,PDRG1,ZMIZ1,TAF6,CDK2,ZNF598 |
| 1.004e-02 | -4.60 | GSE45365_CD8A_DC_VS_CD11B_DC_UP | MSigDB lists | GSE45365_CD8A_DC_VS_CD11B_DC_UP | 173 | 38 | 17377 | 2626 |
PKP4,TRIP12,HJURP,BABAM1,GSPT2,DBF4,DHX8,CYCS,CCNB1,ANKIB1,PAPOLA,MOAP1,TPST1,MAML1,NDUFA3,MRPL32,UBE2QL1,SNX8,TTPAL,GCC2,DDX24,TNFAIP3,USP42,POLR2D,RPL6,GMFB,PBRM1,SEPT7,ANLN,RFC2,PSMB3,SUPT16H,KIF18B,TTLL4,CHCHD1,CNOT6,UBE2C,MZT2B |
| 1.004e-02 | -4.60 | GSE5589_IL6_KO_VS_IL10_KO_LPS_AND_IL10_STIM_MACROPHAGE_180MIN_UP | MSigDB lists | GSE5589_IL6_KO_VS_IL10_KO_LPS_AND_IL10_STIM_MACROPHAGE_180MIN_UP | 184 | 40 | 17377 | 2626 |
MBD1,RAC1,LAGE3,ATG2B,ABHD14B,MAP1LC3B,RAPGEF6,EDC3,RPL11,STARD9,PTEN,TBC1D14,SUCLG2,KIFAP3,GLTP,FNIP2,RNF19A,MRPL11,SGCB,LRSAM1,NDUFA3,MLEC,PBXIP1,MFNG,USP22,DDX23,CSK,SCAP,STK38,FAM3C,PRPS2,DTD1,CNOT6,SCARB1,TRIM32,MAP3K5,YWHAH,NGLY1,BRD9,RNF14 |
| 1.004e-02 | -4.60 | GSE557_WT_VS_CIITA_KO_DC_DN | MSigDB lists | GSE557_WT_VS_CIITA_KO_DC_DN | 184 | 40 | 17377 | 2626 |
ZBTB10,PKP4,C19orf53,SLC41A1,DNAJB2,SRGN,ARID5A,VTI1A,RGS2,IL21R,DLG5,UBXN2A,DAD1,TBC1D14,BRI3,CDC25B,PLCL2,MSH6,MAPRE2,HMGN5,ERLIN1,COQ10B,EMP3,LNX2,KRAS,OGDH,STK17B,EPB41,SH3BP5,PDLIM1,CLK3,DUSP3,MFAP1,PPM1G,PML,NCOA1,DMWD,EHD4,ABCA1,CPEB2 |
| 1.004e-02 | -4.60 | GSE40274_FOXP3_VS_FOXP3_AND_GATA1_TRANSDUCED_ACTIVATED_CD4_TCELL_DN | MSigDB lists | GSE40274_FOXP3_VS_FOXP3_AND_GATA1_TRANSDUCED_ACTIVATED_CD4_TCELL_DN | 184 | 40 | 17377 | 2626 |
PKP4,DNMT3A,GADD45G,ARID5A,PLAGL2,HMGN3,KTN1,PIP4K2A,MXD1,HOMER1,SIAH1,RIMS3,DAPK1,TTC3,ALDH18A1,TPCN1,NSUN4,DVL2,MRPL32,ABCC1,SPTAN1,UBQLN4,HEMK1,CELSR2,BIRC3,ERF,MAP4K3,RAB3IP,SOX4,PRMT2,ANKRD46,ZMYM3,GEMIN5,INF2,ETS2,TULP3,WDR59,B4GALT3,PTOV1,TIGD2 |
| 1.004e-02 | -4.60 | GSE46606_DAY1_VS_DAY3_CD40L_IL2_IL5_STIMULATED_IRF4HIGH_BCELL_DN | MSigDB lists | GSE46606_DAY1_VS_DAY3_CD40L_IL2_IL5_STIMULATED_IRF4HIGH_BCELL_DN | 184 | 40 | 17377 | 2626 |
DDX58,ZNF207,RHOG,MAX,PLXNC1,TMEM184B,AGRN,ARID5A,C5orf30,TAF6L,HEATR5B,RFWD3,CLIC4,TIMELESS,TTC4,APOOL,ZNF710,MVP,TIPARP,PPA1,TRIM14,CGGBP1,PPIF,ENPP4,RFC3,TSPAN31,SLC25A22,RAB1A,ASB13,PI4K2A,OPTN,TRIM26,RBL1,FAM3C,MAPK6,PML,TMEM219,MAP3K5,RNF139,LRP8 |
| 1.004e-02 | -4.60 | GSE27786_ERYTHROBLAST_VS_MONO_MAC_DN | MSigDB lists | GSE27786_ERYTHROBLAST_VS_MONO_MAC_DN | 184 | 40 | 17377 | 2626 |
CDS2,AGTRAP,KLF13,PCSK7,POMP,SLC35B2,EIF1B,AP3S1,GIT2,RNF103,HEATR5B,C2orf68,FAM192A,FBXL6,EI24,AP1M1,AKR1B1,CABLES2,CNOT6L,LDLRAD3,TRIM14,GM2A,CFL1,TSHZ1,CCT2,KLF10,EMB,ABHD11,DCLRE1C,UTP3,EIF3A,TIMM13,STK38,NSMCE2,APPL2,PPP1R11,CHMP7,NRBP1,NUDT3,ZBTB24 |
| 1.004e-02 | -4.60 | GSE3982_EOSINOPHIL_VS_DC_DN | MSigDB lists | GSE3982_EOSINOPHIL_VS_DC_DN | 184 | 40 | 17377 | 2626 |
ST13,NQO1,UGP2,ADO,DUSP22,PARN,RAB11A,TFRC,COPB2,RPN1,SLC31A1,MDM2,LRRC8D,HADHB,TFG,GM2A,CSNK1G3,TRIM14,NIPSNAP1,ATP6V1G1,METTL1,DCTD,UTP3,MTX1,TXNL4A,CLNS1A,RHEB,PSMC4,FBXO21,DAP3,KPNA4,CERS6,ACOX1,STAT6,MPV17,MDH1,SCARB1,EHD4,CCNB2,PDSS2 |
| 1.007e-02 | -4.60 | SNAI1 (snail family transcriptional repressor 1) | protein interactions | 6615 | 68 | 19 | 17029 | 2761 |
TGFB1,USP7,TNFAIP3,AKT2,SUZ12,USP10,RCOR1,CSNK2A1,SIRT2,RCOR3,HMG20A,BRMS1,MDM2,PALB2,XRCC3,USP11,CTDSP2,DNMT1,HDAC2 |
| 1.007e-02 | -4.60 | COPS7B (COP9 signalosome subunit 7B) | protein interactions | 64708 | 68 | 19 | 17029 | 2761 |
COPS8,EWSR1,ASPM,CUL3,CUL1,KRAS,PMF1,APP,BTBD1,SPAG5,DST,FBXO7,DDA1,DCAF11,FEM1B,YWHAZ,COPS6,UBE2M,DDB1 |
| 1.007e-02 | -4.60 | RABEP1 (rabaptin, RAB GTPase binding effector protein 1) | protein interactions | 9135 | 68 | 19 | 17029 | 2761 |
TSC2,GGA1,DCTN2,SMU1,RCOR1,PLEC,GGA2,RAB1A,PSMD9,RUFY1,GIT2,TRIM26,GRIPAP1,RABGAP1L,RAB4A,EXOC4,ECPAS,SMURF1,SRPK2 |
| 1.007e-02 | -4.60 | SNAP23 (synaptosome associated protein 23) | protein interactions | 8773 | 68 | 19 | 17029 | 2761 |
CHMP2A,HNRNPAB,TLK1,TMEM216,KRAS,UBQLN2,DUSP22,MATR3,SRSF1,KIF5B,CCP110,SYNCRIP,NSF,SNAP23,FAM3C,STX18,PTAR1,PSAP,SNAPIN |
| 1.007e-02 | -4.60 | AP3B1 (adaptor related protein complex 3 subunit beta 1) | protein interactions | 8546 | 68 | 19 | 17029 | 2761 |
SKA3,AP3M2,DDX20,JMJD6,EIF2AK1,ARF1,SEPT7,AP3S1,CSNK1A1,CDK11A,CDC73,PIP4K2A,AP3S2,ARF5,CENPJ,MFAP1,YWHAZ,LRSAM1,ARRB2 |
| 1.007e-02 | -4.60 | AGO3 (argonaute 3, RISC catalytic component) | protein interactions | 192669 | 68 | 19 | 17029 | 2761 |
EIF3L,LONRF3,PHB2,PSPC1,AGO2,SF3B6,CUL3,MYH9,BRCA1,DNAJA1,AP3S1,CLNS1A,CAND1,DDOST,STK38,FKBP5,RUVBL2,TUBB,SPTAN1 |
| 1.007e-02 | -4.60 | RPS6KA3 (ribosomal protein S6 kinase A3) | protein interactions | 6197 | 68 | 19 | 17029 | 2761 |
PDPK1,METTL1,HMGN1,WDYHV1,RPS6KA1,TRIM11,ZMYM5,GBA,ATP5PF,MAPK14,MAPK3,HMGN2,H2AFX,STK11,YBX1,PPP6R2,CREB1,MAPK1,CDC37 |
| 1.008e-02 | -4.60 | G1/S DNA Damage Checkpoints | REACTOME pathways | R-HSA-69615 | 67 | 19 | 10287 | 1696 |
PSMA8,PSMB7,PSMA1,PSMB9,PSMD9,PSMB3,PSMC4,PSMD2,PSMA6,CCNA2,PSMD1,MDM2,RPS27A,PSMD3,PSMD8,CDKN1B,CHEK2,CDK2,PSMC1 |
| 1.010e-02 | -4.60 | Regulation of TP53 Expression and Degradation | REACTOME pathways | R-HSA-6806003 | 36 | 12 | 10287 | 1696 |
PDPK1,PPP2CA,USP7,MDM2,CCNA2,RPS27A,AKT2,RFFL,CHEK2,CDK2,CDKN2A,MLST8 |
| 1.011e-02 | -4.59 | GO_KINESIN_BINDING | MSigDB lists | GO_KINESIN_BINDING | 30 | 10 | 17377 | 2626 |
NEK6,KIF18B,PRC1,FAM83D,NUP62,KIFAP3,ACTB,KTN1,LRP8,JAKMIP1 |
| 1.011e-02 | -4.59 | REACTOME_MAPK_TARGETS_NUCLEAR_EVENTS_MEDIATED_BY_MAP_KINASES | MSigDB lists | REACTOME_MAPK_TARGETS_NUCLEAR_EVENTS_MEDIATED_BY_MAP_KINASES | 30 | 10 | 17377 | 2626 |
PPP2CA,DUSP3,RPS6KA1,MEF2A,ELK1,CREB1,MAPK1,ATF2,MAPK14,MAPK3 |
| 1.011e-02 | -4.59 | PID_AURORA_A_PATHWAY | MSigDB lists | PID_AURORA_A_PATHWAY | 30 | 10 | 17377 | 2626 |
MDM2,BIRC5,TACC1,TPX2,AURKB,CDC25B,BRCA1,PRKACA,OAZ1,TACC3 |
| 1.011e-02 | -4.59 | GO_NEGATIVE_REGULATION_OF_TOR_SIGNALING | MSigDB lists | GO_NEGATIVE_REGULATION_OF_TOR_SIGNALING | 30 | 10 | 17377 | 2626 |
TSC1,TMEM127,PDCD6,TSC2,UBR2,PRKAA1,ARNTL,STK11,AKT1S1,EPM2A |
| 1.011e-02 | -4.59 | GO_NUCLEAR_TRANSCRIBED_MRNA_CATABOLIC_PROCESS_EXONUCLEOLYTIC | MSigDB lists | GO_NUCLEAR_TRANSCRIBED_MRNA_CATABOLIC_PROCESS_EXONUCLEOLYTIC | 30 | 10 | 17377 | 2626 |
DCP1A,EXOSC9,CNOT6,EXOSC6,EXOSC7,POLR2G,LSM6,PATL1,EXOSC1,EDC3 |
| 1.011e-02 | -4.59 | GO_SAGA_TYPE_COMPLEX | MSigDB lists | GO_SAGA_TYPE_COMPLEX | 30 | 10 | 17377 | 2626 |
TAF2,SAP130,KAT2A,TAF5L,TAF6L,TAF12,USP22,SUPT7L,TAF6,USP34 |
| 1.011e-02 | -4.59 | GO_G2_DNA_DAMAGE_CHECKPOINT | MSigDB lists | GO_G2_DNA_DAMAGE_CHECKPOINT | 30 | 10 | 17377 | 2626 |
DTL,PLK1,CCNA2,NEK6,CLSPN,BABAM1,TAOK1,BRCA1,BLM,FANCI |
| 1.011e-02 | -4.59 | BIOCARTA_FAS_PATHWAY | MSigDB lists | BIOCARTA_FAS_PATHWAY | 30 | 10 | 17377 | 2626 |
RB1,CASP6,PRKDC,ARHGDIB,FADD,LMNA,FAF1,FAS,SPTAN1,CFLAR |
| 1.011e-02 | -4.59 | GO_ESTABLISHMENT_OF_PROTEIN_LOCALIZATION_TO_VACUOLE | MSigDB lists | GO_ESTABLISHMENT_OF_PROTEIN_LOCALIZATION_TO_VACUOLE | 30 | 10 | 17377 | 2626 |
NAGPA,SCARB2,GCC2,HGS,TNFAIP3,RAB7A,VTI1A,BECN1,SMURF1,VPS25 |
| 1.011e-02 | -4.59 | GO_RNA_POLYMERASE_BINDING | MSigDB lists | GO_RNA_POLYMERASE_BINDING | 30 | 10 | 17377 | 2626 |
PAF1,PPIB,RRN3,PHRF1,YTHDC2,ZNF326,ELP4,CTR9,CDC73,RPRD1B |
| 1.011e-02 | -4.59 | AIMP2 (aminoacyl tRNA synthetase complex interacting multifunctional protein 2) | protein interactions | 7965 | 87 | 23 | 17029 | 2761 |
DEAF1,KARS,LARS,BRCA1,RPL27A,MATR3,APP,BIRC2,PLEKHF2,TERF2IP,EPRS,ATP6V1D,HSPA4,C1orf131,DSN1,IARS,CHD3,QARS,TANK,ACTB,BYSL,LUC7L2,FUBP1 |
| 1.011e-02 | -4.59 | SCN2B (sodium voltage-gated channel beta subunit 2) | protein interactions | 6327 | 87 | 23 | 17029 | 2761 |
NOP9,INTS2,USO1,FOCAD,FAM118B,COG1,DDX20,XPO7,BZW2,CIP2A,UTP20,PTPRF,PLAA,THADA,DNM2,PDS5B,SLC25A51,TNPO3,TNPO2,KNTC1,UBE3C,NR2F2,IPO4 |
| 1.011e-02 | -4.59 | SGTB (small glutamine rich tetratricopeptide repeat containing beta) | protein interactions | 54557 | 87 | 23 | 17029 | 2761 |
PPIB,DNAJC2,RRP15,DDX24,ERF,RB1CC1,FLOT1,MED13L,UHRF1BP1,PNPLA8,PMF1,BRIX1,MAP3K4,UAP1,MTA1,IL6ST,HEXA,ECPAS,ESPL1,C2CD5,PDF,SRSF10,ATP6V1G1 |
| 1.011e-02 | -4.59 | IRF3 (interferon regulatory factor 3) | protein interactions | 3661 | 87 | 23 | 17029 | 2761 |
DDX58,PPIB,DEAF1,EWSR1,XIAP,CUL1,IRF3,SMC2,IRF5,POLR2A,PRDX1,WRNIP1,RB1,SMAD2,TRIM26,RBL1,PIN1,TANK,TICAM1,MAVS,SMAD4,ESYT2,DCTN1 |
| 1.012e-02 | -4.59 | MODULE_261 | MSigDB lists | MODULE_261 | 93 | 23 | 17377 | 2626 |
FYTTD1,ORAI2,SNRNP200,NRAS,KLF10,MIOS,TACC1,NSUN2,DBF4,TRAK1,SLC25A22,BCLAF1,RLF,SEC16A,DHX15,NUP205,CRKL,INTS7,KLHL15,PTPN11,AEN,GLCCI1,NMD3 |
| 1.015e-02 | -4.59 | GO_REGULATION_OF_CELL_DEATH | MSigDB lists | GO_REGULATION_OF_CELL_DEATH | 1423 | 246 | 17377 | 2626 |
TXN,NF1,TSC22D3,TMEM109,XIAP,CSNK2A1,SIRT2,BECN1,MIEN1,BIRC2,PARK7,PRNP,EEF2K,CDK5,DLG5,PA2G4,CDC42,SIVA1,IL6ST,XRCC2,NOC2L,DNM2,OGG1,SENP1,SRPK2,PLK3,PLK1,BAK1,PGAP2,AATF,NCK1,APH1A,AKT2,VHL,DDX20,LRP5,TOPORS,MCL1,AURKB,BRCA1,PRKRA,SOX4,SLC25A5,STK17B,ARF4,KRIT1,BRMS1,RAD18,RPS27A,PRDX5,MYO18A,ITGB1,OGT,ZNF268,CHEK2,CLU,ROCK1,CLN3,ARRB2,TRAF5,PSMC1,ZMAT3,PDCD4,HDAC2,HSPH1,DNAJC5,PHB2,NACA,PRKAA1,VAV2,TRIO,GADD45G,CIB1,TIA1,B4GALT1,CYCS,NOTCH2,PSEN1,APH1B,RHBDD1,APOPT1,JMY,LMNA,CFLAR,TFAP4,CD59,DAD1,HDAC7,ZNF746,DAPK1,ARL6IP1,MSH2,BCL2,KIFAP3,EEF1D,SIGMAR1,RB1CC1,NOA1,ZMYND11,OXR1,KRAS,BCLAF1,ADRB2,SYVN1,PTTG1IP,ELK1,RHOB,IRF5,DAPK3,FAS,CAT,TSC1,PALB2,RBM25,SIAH2,PPP3R1,NUP62,CABIN1,YWHAZ,GPI,MAP3K5,ZNF830,BTBD10,CDKN2A,ADNP2,CHMP2A,CYLD,DNMT3A,TRAF7,NQO1,IVNS1ABP,RAF1,DYNLL1,RPS6KA1,CAST,MAGED1,RAC1,PLAGL2,BCL2L1,LYN,BCAP31,MOAP1,VAV1,RRN3,MDM2,ZNF420,SP100,TNFAIP8,SIAH1,PIN1,KIF14,PDCD2,CDKN1B,PARL,ANKRD13C,CORO1A,TP53BP2,ATF2,F2R,NAA35,TMBIM1,CFL1,HTRA2,ACSL5,PPIF,BIRC3,PPT1,BTG2,MAP4K4,VDAC2,RNPS1,HTATIP2,GLO1,DNAJA1,CHMP4A,HIPK2,GADD45B,STAT1,CHMP4B,TRIM32,NCOA1,PPP5C,SMAD4,CBX4,ZC3HC1,MIF,BCL2L12,GCLM,TMBIM4,CASP6,MECP2,SRSF6,DAP,EYA1,PAWR,SDF2L1,AKT1S1,IP6K2,ETS1,FOXO3,PTPN2,PDCD10,CTNNBL1,KLHL20,PTEN,AXIN2,FEM1B,ARHGEF2,ANXA5,CREB1,CITED2,STAT3,UBE2M,PDPK1,TGFB1,ADAM17,TNFAIP3,HMGN5,NET1,PRKDC,LDHA,RFFL,HEBP2,ARHGEF12,PRMT2,API5,PICALM,FADD,HSPA1B,PDCD6,BIRC5,PRDX3,TFDP1,PML,E2F1,TMEM219,HMGB2,PSAP,YWHAH,IGBP1,HIPK3,TERF1,HRAS,HIGD2A,DDB1,FAF1 |
| 1.016e-02 | -4.59 | Acyl_CoA_acyltransferase | interpro domains | IPR016181 | 44 | 13 | 18492 | 2768 |
NAT14,NAT9,GNPNAT1,KAT2A,KAT7,OAZ2,NAA50,ATE1,NAA20,OAZ1,NAA60,SAT2,NMT2 |
| 1.017e-02 | -4.59 | AACGGTT,MIR-451 | MSigDB lists | AACGGTT,MIR-451 | 10 | 5 | 17377 | 2626 |
SAMD4B,CAB39,YWHAZ,MEX3C,OGT |
| 1.017e-02 | -4.59 | REACTOME_REGULATION_OF_RHEB_GTPASE_ACTIVITY_BY_AMPK | MSigDB lists | REACTOME_REGULATION_OF_RHEB_GTPASE_ACTIVITY_BY_AMPK | 10 | 5 | 17377 | 2626 |
TSC1,PRKAB1,TSC2,RHEB,PRKAA1 |
| 1.017e-02 | -4.59 | HOFMANN_MYELODYSPLASTIC_SYNDROM_HIGH_RISK_UP | MSigDB lists | HOFMANN_MYELODYSPLASTIC_SYNDROM_HIGH_RISK_UP | 10 | 5 | 17377 | 2626 |
CELSR2,ELK1,COIL,OGG1,ZMYM3 |
| 1.017e-02 | -4.59 | BIOCARTA_SKP2E2F_PATHWAY | MSigDB lists | BIOCARTA_SKP2E2F_PATHWAY | 10 | 5 | 17377 | 2626 |
CUL1,RB1,CDK2,TFDP1,E2F1 |
| 1.017e-02 | -4.59 | GO_REGULATION_OF_NECROPTOTIC_PROCESS | MSigDB lists | GO_REGULATION_OF_NECROPTOTIC_PROCESS | 10 | 5 | 17377 | 2626 |
ARHGEF2,BIRC3,BIRC2,FADD,CFLAR |
| 1.017e-02 | -4.59 | GO_KINETOCHORE_ORGANIZATION | MSigDB lists | GO_KINETOCHORE_ORGANIZATION | 10 | 5 | 17377 | 2626 |
SMC2,CENPT,MIS12,CENPF,SMC4 |
| 1.017e-02 | -4.59 | GO_NUCLEAR_PORE_COMPLEX_ASSEMBLY | MSigDB lists | GO_NUCLEAR_PORE_COMPLEX_ASSEMBLY | 10 | 5 | 17377 | 2626 |
NUP153,AHCTF1,NUP205,NUP107,TMEM33 |
| 1.017e-02 | -4.59 | GO_GEMINI_OF_COILED_BODIES | MSigDB lists | GO_GEMINI_OF_COILED_BODIES | 10 | 5 | 17377 | 2626 |
GEMIN5,GEMIN6,DDX20,GEMIN4,GEMIN7 |
| 1.017e-02 | -4.59 | GO_ORGANELLE_INHERITANCE | MSigDB lists | GO_ORGANELLE_INHERITANCE | 10 | 5 | 17377 | 2626 |
VCPIP1,PLK3,YWHAZ,PDCD10,GOLGA2 |
| 1.017e-02 | -4.59 | AAGCCAT,MIR-135A,MIR-135B | MSigDB lists | AAGCCAT,MIR-135A,MIR-135B | 314 | 63 | 17377 | 2626 |
GGNBP2,B4GALT5,ANK3,ADO,SLC39A13,TMEM97,YTHDF3,CSNK1A1,ZNF518A,RAPGEF6,MYEF2,BZW2,SSR1,PAPOLA,MAN1A1,FKBP1A,PRKD3,SIAH1,IL6ST,PIK3R2,SLC44A1,PPP1R12C,PARL,ARHGEF2,JOSD1,NUP153,UBE3C,TMEM9,DRAM2,SP3,GCC2,CREG1,PGGT1B,CIC,NUDT4,TLK1,USP42,SSR2,TOPORS,MTMR12,ELK1,SLC25A5,API5,PATL1,MAT2A,MKNK1,SERTAD2,BRWD1,ORMDL2,TMEM168,GOLGA7,STAT6,HPS5,PTER,CSNK1G1,SOCS4,CHMP4B,ZRANB2,RGL1,NCOA1,MBD6,PPP6R3,BTBD10 |
| 1.018e-02 | -4.59 | GO_CYTOSKELETAL_PROTEIN_BINDING | MSigDB lists | GO_CYTOSKELETAL_PROTEIN_BINDING | 777 | 141 | 17377 | 2626 |
MIB2,RAB14,ADD1,KIF2C,SIRT2,MAP1LC3B,ANKRD23,PRNP,KIFC1,CDK5,CALM2,DST,ABL2,DLG5,RAB8A,NEK6,SYNM,DPYSL2,RCSD1,DNM2,KIF22,RP2,MAST2,OGG1,PLK1,AATF,NCK1,GMFB,KIF15,EZR,BRCA1,ANLN,EPB41,KRIT1,DPYSL3,WAS,KIF18B,MAP4,MYO18A,ITGB1,ACTB,MYL12B,CAPN1,HSPH1,MAPRE1,GMFG,B4GALT1,KIF23,RACGAP1,RAB6A,RGS2,JMY,VASP,KLHL5,ARPC5,KIF13B,CAPZA1,KIFAP3,CYFIP1,WDR1,CAMSAP1,CAPZA2,PLEC,ARPC1A,PHF6,AKAP1,FNTA,GOLGA2,FAM83D,NUP62,MYO9A,NDE1,PDLIM5,ZNF207,WASF2,CORO7,RAB11B,ANK3,TOR1AIP1,ACTR3,MYH9,TWF2,LYN,STMN1,KTN1,KIF14,CORO1A,ABI1,CFL1,PPP1R18,MAPRE2,PSRC1,TUBGCP5,WIPF1,NUSAP1,TMEM201,KIF2A,ATP1A1,CORO1C,TRIM32,PPP5C,REEP4,LRP8,RAD51D,KIF3B,RAE1,DCTN2,PAWR,MYO9B,TUBGCP2,RAB11A,NEIL2,JAKMIP1,CAPN2,KIF5B,STARD9,ADD3,KLHL20,CENPJ,PRC1,ARHGEF2,CNN2,MYO5A,MICAL3,S100A6,SPTAN1,PDLIM2,PPP1R9B,RHOA,WDR81,KIF11,MACF1,MYO1F,INF2,KIF18A,TTLL4,BIRC5,LRPPRC,PKD2,YWHAH,TERF1 |
| 1.020e-02 | -4.59 | UBA | pfam domains | PF00627 | 26 | 9 | 17054 | 2545 |
UBQLN4,HUWE1,UBXN1,RAD23B,UBQLN2,MARK2,USP13,USP5,RAD23A |
| 1.022e-02 | -4.58 | BROWNE_HCMV_INFECTION_4HR_DN | MSigDB lists | BROWNE_HCMV_INFECTION_4HR_DN | 240 | 50 | 17377 | 2626 |
PRKAB1,THOC1,MDH2,ABCC10,SUMO2,AP3M2,SDC2,PCSK7,SLC25A12,TWF2,PPP1R16B,METTL3,KRR1,CDK5,SNUPN,NVL,RABGAP1L,NOC2L,AHDC1,MAST2,ERI3,ZNF710,CITED2,SOCS5,CSTF1,MIOS,KLF10,GALK2,KCNQ1,PLEC,VDAC1,KLF6,TWISTNB,RDH11,DDX23,DDX17,PPP2CA,PARG,ODF2,CAPN7,HMGB2,ZNF268,NCLN,CHEK2,PDXK,TCOF1,RRS1,NR2F2,RUFY3,LRP8 |
| 1.022e-02 | -4.58 | azurophil granule membrane | cellular component | GO:0035577 | 59 | 16 | 18223 | 2701 |
CPNE1,DNAJC5,MANBA,B4GALT1,PSEN1,CMTM6,CPNE3,TMEM179B,MAGT1,DDOST,SURF4,SNAP29,BRI3,ATP6V0C,PSAP,LPCAT1 |
| 1.025e-02 | -4.58 | TPR_REGION | prosite domains | PS50293 | 124 | 27 | 12060 | 1670 |
SRP72,RPAP3,NASP,ST13,LONRF3,CRNKL1,WDTC1,KLC1,CDC23,TANC1,TTC33,PEX5,CDC16,TTC13,CDC27,TONSL,ZC3H7B,TTC9C,OGT,CTR9,FKBP5,TTC3,CABIN1,ANAPC7,TTC4,TTC17,PPP5C |
| 1.026e-02 | -4.58 | GO_PEPTIDYL_SERINE_MODIFICATION | MSigDB lists | GO_PEPTIDYL_SERINE_MODIFICATION | 146 | 33 | 17377 | 2626 |
CLSPN,PRKAA1,CCNB1,CSNK1A1,PRKACA,MAPK14,CDK5,NEK6,BCL2,MAST2,CSNK1G3,MORC3,PLK1,PDPK1,CSNK1G2,MAPKAPK3,PRKDC,AKT2,AURKB,MAP2K2,MASTL,MAPK3,MKNK1,GALNT2,STK38,CSNK1G1,HIPK2,CAB39,CHEK2,MAPK1,CDK2,HIPK3,CSNK1D |
| 1.030e-02 | -4.58 | GCACCTT,MIR-18A,MIR-18B | MSigDB lists | GCACCTT,MIR-18A,MIR-18B | 114 | 27 | 17377 | 2626 |
PHF20L1,EHMT1,C5orf30,UBE2Z,ATXN1,CREBL2,MAP7D1,MEF2D,FAM136A,RHOT1,ASXL2,GIGYF1,SMAP2,FAM192A,SMAD2,ADD3,CDC42,KLHL20,KDM2A,SAR1A,ZNF367,ETV6,ATXN2L,TARDBP,NCOA1,BRWD3,SOCS5 |
| 1.032e-02 | -4.57 | TRNASYNTHILE | prints domains | PR00984 | 2 | 2 | 4652 | 473 |
IARS,IARS2 |
| 1.032e-02 | -4.57 | RIBOSOMALS2 | prints domains | PR00395 | 2 | 2 | 4652 | 473 |
MRPS2,RPSA |
| 1.032e-02 | -4.57 | CYTOFMRPINTP | prints domains | PR01698 | 2 | 2 | 4652 | 473 |
CYFIP1,CYFIP2 |
| 1.032e-02 | -4.57 | RAD23PROTEIN | prints domains | PR01839 | 2 | 2 | 4652 | 473 |
RAD23B,RAD23A |
| 1.032e-02 | -4.57 | VACATPASE | prints domains | PR00122 | 2 | 2 | 4652 | 473 |
ATP6V0B,ATP6V0C |
| 1.032e-02 | -4.57 | ERK1ERK2MAPK | prints domains | PR01770 | 2 | 2 | 4652 | 473 |
MAPK1,MAPK3 |
| 1.032e-02 | -4.57 | GALCTOKINASE | prints domains | PR00473 | 2 | 2 | 4652 | 473 |
GALK1,GALK2 |
| 1.032e-02 | -4.57 | GLHYDRLASE20 | prints domains | PR00738 | 2 | 2 | 4652 | 473 |
HEXA,HEXB |
| 1.032e-02 | -4.57 | ATPase activity, coupled to transmembrane movement of ions, rotational mechanism | molecular function | GO:0044769 | 34 | 11 | 17224 | 2647 |
ATP6V0B,ATP5MC3,ATP6V0A1,ATP6V0A2,ATP6V0C,ATP5F1B,ATP5F1A,ATP6V1B2,ATP6V1C1,ATP6V0E1,ATP6V0D1 |
| 1.032e-02 | -4.57 | GO_ENDOSOME_ORGANIZATION | MSigDB lists | GO_ENDOSOME_ORGANIZATION | 58 | 16 | 17377 | 2626 |
CHMP2A,CLCN3,PDCD6IP,CHMP2B,RAB5B,RAB11A,STAM,VPS25,RAB22A,TMEM127,CHMP4A,HGS,CHMP4B,VPS4A,CHMP7,ALS2 |
| 1.032e-02 | -4.57 | CCAATNNSNNNGCG_UNKNOWN | MSigDB lists | CCAATNNSNNNGCG_UNKNOWN | 58 | 16 | 17377 | 2626 |
SAP130,PCNA,PSRC1,SMAD2,CLSPN,UTP18,NCK1,IL6ST,CDK2AP2,KHSRP,PIK3IP1,LMAN1,ASXL2,THAP5,DNAJB9,ARL6IP6 |
| 1.032e-02 | -4.57 | GO_NUCLEOLAR_PART | MSigDB lists | GO_NUCLEOLAR_PART | 58 | 16 | 17377 | 2626 |
UBTF,CDKN2AIP,EIF3L,NOL11,POLR2L,UTP18,CD3EAP,POLR2K,TBL3,POP7,UTP15,POLR1B,FBL,GAR1,ZNRD1,TWISTNB |
| 1.032e-02 | -4.57 | HALLMARK_MYC_TARGETS_V2 | MSigDB lists | HALLMARK_MYC_TARGETS_V2 | 58 | 16 | 17377 | 2626 |
SRM,PLK1,PPAN,NOP2,TMEM97,TBRG4,CBX3,UTP20,SLC19A1,PA2G4,FARSA,NIP7,MCM5,TCOF1,BYSL,IPO4 |
| 1.037e-02 | -4.57 | post-translational protein modification | biological process | GO:0043687 | 440 | 85 | 17256 | 2622 |
KCTD7,RAB11B,ADAM10,PRKCSH,WDTC1,CUL1,TGOLN2,APP,KTN1,FBXO22,RAB8A,APLP2,PSMA6,PSMD1,DDA1,SOCS6,FBXW2,PDIA6,ANKRD9,ASB6,SPSB3,COPS8,RBX1,PSMA8,VHL,CUL3,PSMB7,SUMF2,ICMT,CCNF,ASB13,RAB1A,PSMB9,BTBD1,STT3A,PSMD8,PSMD3,VIPAS39,KLHL42,FBXL3,COPS6,PSMC1,DCAF5,WSB2,KLHL21,SDC2,SUMF1,WDR5,PSMD9,RAB11A,RHBDD1,ATG4A,GOLM1,DTL,PSMD2,KLHL5,KLHL20,FBXO7,FEM1B,COPS7B,FBXL7,FBXL19,UBE2M,APOL1,SOCS5,DCAF6,CNTN5,DCAF8,PSMA1,FBXO9,MEN1,LY6E,ARSK,PSMB3,CAND1,PSMC4,NUCB1,FBXO21,FBXO41,KEAP1,KBTBD7,DCAF11,FN3KRP,WIPI2,DDB1 |
| 1.040e-02 | -4.57 | SANT_dom | interpro domains | IPR017884 | 26 | 9 | 18492 | 2768 |
RCOR1,DNAJC2,NCOR2,MIER2,TRERF1,RCOR3,MTA1,MTA2,MIER1 |
| 1.040e-02 | -4.57 | Bromodomain_CS | interpro domains | IPR018359 | 26 | 9 | 18492 | 2768 |
BRD4,BRWD1,KAT2A,BRD2,BRPF3,BAZ2A,BAZ1B,SMARCA4,PBRM1 |
| 1.041e-02 | -4.56 | regulation of helicase activity | biological process | GO:0051095 | 10 | 5 | 17256 | 2622 |
CHTOP,MCM2,POT1,MSH6,MSH2 |
| 1.041e-02 | -4.56 | IRES-dependent viral translational initiation | biological process | GO:0075522 | 10 | 5 | 17256 | 2622 |
EIF3D,EIF2D,PCBP2,EIF3A,MCTS1 |
| 1.041e-02 | -4.56 | mitotic nuclear envelope reassembly | biological process | GO:0007084 | 10 | 5 | 17256 | 2622 |
ANKLE2,PPP2CA,REEP4,BANF1,LMNA |
| 1.041e-02 | -4.56 | regulation of protein K63-linked ubiquitination | biological process | GO:1900044 | 10 | 5 | 17256 | 2622 |
TRIP12,PLAA,GPS2,PARP10,BIRC2 |
| 1.041e-02 | -4.56 | deoxyribonucleoside monophosphate biosynthetic process | biological process | GO:0009157 | 10 | 5 | 17256 | 2622 |
DCTD,TK1,DCK,DUT,HDDC2 |
| 1.041e-02 | -4.56 | histone H3-K9 methylation | biological process | GO:0051567 | 10 | 5 | 17256 | 2622 |
BEND3,SUV39H2,KDM3A,ARID4A,EHMT1 |
| 1.041e-02 | -4.56 | Golgi inheritance | biological process | GO:0048313 | 10 | 5 | 17256 | 2622 |
PLK3,VCPIP1,YWHAZ,PDCD10,GOLGA2 |
| 1.042e-02 | -4.56 | TIEN_INTESTINE_PROBIOTICS_6HR_DN | MSigDB lists | TIEN_INTESTINE_PROBIOTICS_6HR_DN | 157 | 35 | 17377 | 2626 |
RECQL,RWDD1,ANXA6,HEXB,HAUS4,PLXNA1,EIF1B,SRRT,DNAJB9,PSMD1,MCM5,RBM34,CTR9,RBM15,RNF5,RYBP,DHX29,ATP2C1,CIRBP,ADSL,CADM1,SRSF5,FXR1,MRPS14,PICALM,RDH11,MAP3K4,ATP6V1D,PPP2R5A,SPATA2,MAPK6,LRPPRC,RBMS1,ANP32E,PSMC1 |
| 1.043e-02 | -4.56 | transferase activity, transferring phosphorus-containing groups | molecular function | GO:0016772 | 1011 | 182 | 17224 | 2647 |
POLA2,CCNC,FGFR1OP,MAP3K7CL,HMGXB3,CSNK2A1,NANS,CDIPT,CCNB1,MAPK14,POLR3K,PAPOLA,EEF2K,CDK5,ABL2,NEK6,CDC42,PIK3R2,UPRT,MAST2,ZNRD1,FGFR1OP2,CDC37,SRPK2,PLK3,PLK1,AKT2,PBK,TLK1,AURKB,PRPSAP1,STK17B,PRIM1,MAP3K4,MKNK1,LIMK1,BAZ1B,CAB39,CRCP,STK11,CHEK2,RNASEL,ROCK1,CHPT1,PFKP,SEPHS2,PIGN,POLR2K,PRKAA1,TRIO,CERK,CDK13,ADCK5,EIF2AK4,CHKA,DAPK1,PIGG,PCYT2,ALDH18A1,PIKFYVE,PHKG2,N4BP2,CSNK1G3,TERF2,POLR2I,PRIM2,MAPKAPK3,COQ8A,PGS1,PIP4K2C,MAP4K3,EIF2AK1,PKM,MAP2K2,TWISTNB,DAPK3,PI4K2A,MASTL,UAP1,POLR2J,CSK,DCK,CSNK1G1,PRPS2,FN3KRP,SAMD8,MAP3K5,CDK2,CCNB2,NRBP1,PRKAB1,KARS,TP53RK,UGP2,RAF1,RPS6KA1,RAC1,UCK2,UCK1,ZFYVE21,CHKB,ADPGK,PRKACA,LYN,CPNE3,VAV1,FLAD1,PRKD3,PDK2,CCNA2,CD3EAP,CDKN1B,RPAP1,CDK12,SCYL3,ULK3,POLR2L,POLR2G,CGAS,MAP4K4,TAOK1,POLR2D,PFKFB3,GALK2,PKMYT1,POLG2,TRIM28,JAK1,CLK3,HIPK2,FASTK,STK38,PDXK,MAPK1,CSNK1D,PRPF4B,POLQ,GALK1,CMAS,CDS2,SCYL1,GNE,IP6K2,CDK11B,CSNK1A1,PMVK,PIP4K2A,SCYL2,NEXMIF,TUT4,PIP5K1C,FASTKD3,CCNK,FGFR3,GRK2,PTPN11,PTGES3,POLR1B,MAP3K14,GTF2H2,CAMK2G,PDPK1,CSNK1G2,TK1,GUK1,POLK,NEK7,PRKDC,TBRG4,NADK2,POLR3GL,CDK11A,MARK2,POLR2A,MAPK3,NEK1,POLE,LTBP4,MAPK6,RPS6KC1,TERF1,HIPK3 |
| 1.043e-02 | -4.56 | MYCL (MYCL proto-oncogene, bHLH transcription factor) | protein interactions | 4610 | 41 | 13 | 17029 | 2761 |
KIF5B,CTU2,MAX,FOXK1,JAZF1,KLC1,TAF5L,SUPT20H,RUVBL2,SUPT7L,MXD1,MEAF6,FBRS |
| 1.043e-02 | -4.56 | CSTF3 (cleavage stimulation factor subunit 3) | protein interactions | 1479 | 41 | 13 | 17029 | 2761 |
UNK,VHL,E2F4,CUL3,RNPS1,CCNL2,SYMPK,CDC73,PABPC1,POLR2A,CDC5L,CSTF1,PAPOLA |
| 1.043e-02 | -4.56 | APOOL (apolipoprotein O like) | protein interactions | 139322 | 41 | 13 | 17029 | 2761 |
SLC39A9,CHCHD3,IMMT,STARD7,CHCHD2,MTX1,APOOL,RHOT1,CHCHD6,MTX2,GLMP,ECH1,STOML2 |
| 1.043e-02 | -4.56 | RNF138 (ring finger protein 138) | protein interactions | 51444 | 41 | 13 | 17029 | 2761 |
COPS8,LYAR,TRIM8,TULP3,WDR4,LNX2,JMJD6,FAM136A,COPS6,RBBP4,MAPK14,APP,RAD51D |
| 1.043e-02 | -4.56 | IRAK2 (interleukin 1 receptor associated kinase 2) | protein interactions | 3656 | 41 | 13 | 17029 | 2761 |
SNRNP200,SMAD2,TNFAIP3,STT3A,COQ8A,SESTD1,TARDBP,TOLLIP,SMURF1,PSEN1,HRAS,N4BP2L2,CDC37 |
| 1.043e-02 | -4.56 | PPP1R9B (protein phosphatase 1 regulatory subunit 9B) | protein interactions | 84687 | 41 | 13 | 17029 | 2761 |
ANKRD28,PCM1,SHC1,PPP1R2,SUZ12,MYH9,TGOLN2,BRCA1,CAPZA2,MAPK1,PRKACA,WDR48,CDKN2A |
| 1.043e-02 | -4.56 | DDX58 (DExD/H-box helicase 58) | protein interactions | 23586 | 41 | 13 | 17029 | 2761 |
DDX58,UBE2D3,CYLD,MEX3C,NLRC5,TIA1,IRF3,TRIM32,MAVS,RNF135,USP21,ISG15,WRNIP1 |
| 1.043e-02 | -4.56 | CALD1 (caldesmon 1) | protein interactions | 800 | 41 | 13 | 17029 | 2761 |
RPA2,SHC1,TM9SF4,CSNK2A1,MYH9,PRKACA,KIF11,TERF1,POT1,TACC3,ISG15,TERF2,RPA1 |
| 1.043e-02 | -4.56 | APEH (acylaminoacyl-peptide hydrolase) | protein interactions | 327 | 41 | 13 | 17029 | 2761 |
CYHR1,KARS,PPM1G,UBA5,STAT1,USP39,PAWR,JMJD6,BRCA1,PREPL,TOLLIP,TARS,CAND1 |
| 1.043e-02 | -4.56 | CLASP2 (cytoplasmic linker associated protein 2) | protein interactions | 23122 | 41 | 13 | 17029 | 2761 |
FEZ2,MAPRE2,MAPRE1,GORASP1,CENPJ,GOPC,CSNK2A1,ARMH3,MPG,SMURF1,MARK2,DCTN1,SRPK2 |
| 1.045e-02 | -4.56 | Cell cycle - G1/S transition | KEGG pathways | hsa_M00692 | 13 | 6 | 7161 | 1149 |
RB1,CDK2,E2F2,RBL1,E2F1,E2F3 |
| 1.045e-02 | -4.56 | Cell cycle - G1/S transition | KEGG pathways | M00692 | 13 | 6 | 7161 | 1149 |
RB1,CDK2,E2F2,RBL1,E2F1,E2F3 |
| 1.046e-02 | -4.56 | GO_NIK_NF_KAPPAB_SIGNALING | MSigDB lists | GO_NIK_NF_KAPPAB_SIGNALING | 83 | 21 | 17377 | 2626 |
COPS8,BIRC3,PSMA8,ZFP91,PSMB7,PSMA1,CUL1,PSMB9,PSMD9,BIRC2,PSMB3,PSMC4,PSMD2,PSMA6,PSMD1,RPS27A,PSMD3,PSMD8,MAP3K14,PSMC1,UBE2M |
| 1.046e-02 | -4.56 | CAGGGTC,MIR-504 | MSigDB lists | CAGGGTC,MIR-504 | 83 | 21 | 17377 | 2626 |
IER2,ZMYND11,MECP2,SUGP2,KLHL18,RRAGC,KLF13,SLC25A22,KDM1B,EPB41,HMGN2,NRF1,CHD3,DBNDD1,CSNK1G1,OGT,CNOT6,COPS7B,H3F3A,MCMBP,CAMK2G |
| 1.046e-02 | -4.56 | chr1p35 | MSigDB lists | chr1p35 | 83 | 21 | 17377 | 2626 |
MRPS15,SLC2A1,WDTC1,FAM76A,EBNA1BP2,STMN1,BSDC1,MEAF6,SMAP2,RPA2,DNAJC8,TMEM54,PPP1R8,GMEB1,SRSF4,TXLNA,MECR,TAF12,RBBP4,NUDC,S100PBP |
| 1.047e-02 | -4.56 | Lagging Strand Synthesis | REACTOME pathways | R-HSA-69186 | 20 | 8 | 10287 | 1696 |
POLA2,RPA2,PCNA,RFC3,PRIM2,RFC2,PRIM1,RPA1 |
| 1.048e-02 | -4.56 | cellular response to hypoxia | biological process | GO:0071456 | 189 | 41 | 17256 | 2622 |
UBE2D3,DNMT3A,PHB2,PRKAA1,SIRT2,SLC29A1,CCNB1,PSMD9,FOXO3,LMNA,CFLAR,PSMD2,CCNA2,PSMA6,PSMD1,MDM2,SUV39H2,TIGAR,PTEN,BCL2,CITED2,HP1BP3,PLK3,RBX1,PSMA8,VHL,ERO1A,PSMB7,PSMA1,PSMB9,PSMB3,PSMC4,RPS27A,PSMD8,PSMD3,HIPK2,E2F1,RBPJ,PSMC1,CPEB2,EGLN1 |
| 1.048e-02 | -4.56 | GSE9650_EFFECTOR_VS_MEMORY_CD8_TCELL_DN | MSigDB lists | GSE9650_EFFECTOR_VS_MEMORY_CD8_TCELL_DN | 190 | 41 | 17377 | 2626 |
SLC12A7,DDX47,DNAJB2,MOGS,UCK1,RGS2,C19orf48,PABPC4,PRNP,CTSS,GART,EIF2S2,HDAC7,SLC44A1,BCL2,FBL,EIF5,METTL1,ATP13A1,CAMSAP1,RPL6,ADRB2,ARID1A,VKORC1,ODC1,KLF6,GAR1,LUC7L,RHOB,XRCC5,PCM1,ETS2,AXIN1,SIAH2,RNF38,DDX5,SMAD1,HEXA,TOB1,EYA2,IPO4 |
| 1.048e-02 | -4.56 | GSE360_L_MAJOR_VS_B_MALAYI_HIGH_DOSE_MAC_DN | MSigDB lists | GSE360_L_MAJOR_VS_B_MALAYI_HIGH_DOSE_MAC_DN | 190 | 41 | 17377 | 2626 |
CHMP2A,NDUFB6,RAE1,UBXN1,SNX15,CCNB1,NDUFS7,SF3B2,FARSA,NDUFV1,EXOSC7,MED8,UTP18,BANF1,ARHGEF1,MEA1,MRPS27,AHCY,CDC25B,CYC1,ATP6V0D1,NIPSNAP1,PTPN18,RHOA,PRRC2A,MYBL2,ESYT1,NEU1,IRF5,CHAF1A,MFN2,PI4K2A,EIF3K,DHX16,PSMD8,GLG1,IMPDH1,IDH3B,HEXA,AP2S1,RNF114 |
| 1.048e-02 | -4.56 | GSE360_L_MAJOR_VS_B_MALAYI_LOW_DOSE_DC_DN | MSigDB lists | GSE360_L_MAJOR_VS_B_MALAYI_LOW_DOSE_DC_DN | 190 | 41 | 17377 | 2626 |
TMEM106C,H2AFZ,NDUFB6,YTHDC2,DHX8,XPO7,PMVK,REEP5,MYL6B,MOAP1,VAV1,ZNF428,RRN3,HADHB,TRA2B,SPTSSA,CNPY3,EEF1D,MED22,KDELR1,KDM3B,MLEC,PRIM2,KAT2A,WDR1,SLC16A7,SEPT8,ARHGDIB,OGDH,RDH11,AKAP1,ALG3,AHNAK,RBL1,LPCAT4,MPV17,LRPPRC,MDH1,CHEK2,PLOD3,ARRB2 |
| 1.048e-02 | -4.56 | GSE5679_PPARG_LIGAND_ROSIGLITAZONE_VS_ROSIGLITAZONE_AND_RARA_AGONIST_AM580_TREATED_DC_UP | MSigDB lists | GSE5679_PPARG_LIGAND_ROSIGLITAZONE_VS_ROSIGLITAZONE_AND_RARA_AGONIST_AM580_TREATED_DC_UP | 190 | 41 | 17377 | 2626 |
PKP4,LIME1,PLXNC1,LUZP1,SLC41A1,SRGN,UFC1,MAGED1,COPE,KCTD17,DNAJC24,UBE2I,LCLAT1,TFRC,FKBP1A,SNRNP25,TNFAIP8,VMP1,PTPN11,EI24,OSTC,MGAT5,UBE2M,POU2AF1,MAPRE2,SEPT9,UBE2V1,IL12RB1,PHF6,GLOD4,IDE,MTHFD2,CSK,GADD45B,PRPS2,ITGB1,SLC25A19,ATF6,SPCS3,TMEM101,PGAM1 |
| 1.048e-02 | -4.56 | GSE7460_FOXP3_MUT_VS_WT_ACT_WITH_TGFB_TCONV_UP | MSigDB lists | GSE7460_FOXP3_MUT_VS_WT_ACT_WITH_TGFB_TCONV_UP | 190 | 41 | 17377 | 2626 |
SEC61G,SRGN,ARID5A,AGFG1,SDF2L1,POMP,NCAPG,PPP1R16B,TMEM165,NPLOC4,EIF2S2,IARS,SUV39H2,VMP1,DAD1,LPIN2,RAD23B,RRBP1,F2R,C12orf75,ZNF770,MLEC,SEC61B,ELL2,LRRC1,VKORC1,PDE3B,EIF3A,HSPA1B,TAF2,NUCB1,STT3A,GADD45B,VCPIP1,MEGF9,PKD2,RBPJ,NAA20,CHPT1,CABLES1,VPS29 |
| 1.049e-02 | -4.56 | peptide-lysine-N-acetyltransferase activity | molecular function | GO:0061733 | 62 | 17 | 17224 | 2647 |
KAT2A,KAT7,TEX30,NAA50,OGT,ELP4,KANSL2,TAF5L,EDF1,TAF6L,NCOA1,TAF12,USP22,WDR5,SUPT7L,ATF2,NAA60 |
| 1.049e-02 | -4.56 | lysosomal lumen | cellular component | GO:0043202 | 95 | 23 | 18223 | 2701 |
ACP2,AGRN,GALC,PPT1,MANBA,HEXB,GBA,SDC2,ASAH1,MAN2B1,GYG1,NEU1,CTSL,GNS,SCARB2,SGSH,CTSS,NAGLU,CTSA,PSAP,HEXA,CHID1,GM2A |
| 1.050e-02 | -4.56 | ATP hydrolysis coupled proton transport | biological process | GO:0015991 | 30 | 10 | 17256 | 2622 |
ATP6V0B,ATP1A1,ATP5MC3,ATP6V0A2,ATP6V0A1,ATP6V0C,ATP6V1C1,ATP6V1B2,ATP6V0E1,ATP6V0D1 |
| 1.050e-02 | -4.56 | mRNA polyadenylation | biological process | GO:0006378 | 30 | 10 | 17256 | 2622 |
PAF1,GRSF1,CPSF4,AHCYL1,SYMPK,APP,PABPC1,CDC73,ZC3H3,PAPOLA |
| 1.051e-02 | -4.56 | GSE32901_TH1_VS_TH17_ENRICHED_CD4_TCELL_UP | MSigDB lists | GSE32901_TH1_VS_TH17_ENRICHED_CD4_TCELL_UP | 168 | 37 | 17377 | 2626 |
CYTIP,CAST,VTI1A,MYH9,TOP2B,MAPK14,CHD1,PAIP1,XPR1,FBXO22,ADD3,RCSD1,TAF5L,CORO1A,PLCL2,GNAI2,ABI1,SMC4,CSNK1G2,ELOVL5,LONRF3,RNF25,MIER1,TAOK1,CUL3,FAM133B,BRMS1,ADSS,TMEM168,JAK1,STK38,DDX5,PPP6R3,PPP6R2,TSEN15,RAD51D,ZC3HAV1 |
| 1.052e-02 | -4.55 | GO_REGULATION_OF_PROTEIN_ACETYLATION | MSigDB lists | GO_REGULATION_OF_PROTEIN_ACETYLATION | 63 | 17 | 17377 | 2626 |
TGFB1,KAT2A,EID1,MECP2,WBP2,CTCF,BRCA1,SOX4,PARK7,MAPK3,IWS1,TERF2IP,NOC2L,BRD7,RUVBL2,SMAD4,HDAC2 |
| 1.052e-02 | -4.55 | PID_ERA_GENOMIC_PATHWAY | MSigDB lists | PID_ERA_GENOMIC_PATHWAY | 63 | 17 | 17377 | 2626 |
NCOR2,ABCA3,PHB2,BRCA1,AP1B1,MPG,DDX17,PCNA,MTA1,SAFB,AXIN2,ANP32A,NCOA1,SMAD4,UBE2M,NCOA2,EBAG9 |
| 1.052e-02 | -4.55 | GSE10240_IL17_VS_IL17_AND_IL22_STIM_PRIMARY_BRONCHIAL_EPITHELIAL_CELLS_UP | MSigDB lists | GSE10240_IL17_VS_IL17_AND_IL22_STIM_PRIMARY_BRONCHIAL_EPITHELIAL_CELLS_UP | 179 | 39 | 17377 | 2626 |
WSB2,C1orf74,NAT9,GPR132,MAX,ADD1,LUZP1,GXYLT1,RHOC,ANKH,PTTG1,ARID5A,HEATR5B,WWP2,CCNK,VAV1,ATP6V0B,HOMER1,WDR44,SEH1L,VPS13B,RBX1,TSPYL4,COQ10B,RFXANK,SCFD2,SLC26A6,C1orf122,KIF18B,ERGIC3,NFIL3,ZDHHC7,ACBD4,MEGF9,FAM126A,KLHDC4,REEP4,GEN1,ZC3HAV1 |
| 1.052e-02 | -4.55 | GSE18893_TCONV_VS_TREG_2H_CULTURE_UP | MSigDB lists | GSE18893_TCONV_VS_TREG_2H_CULTURE_UP | 179 | 39 | 17377 | 2626 |
POLA2,MUT,CASP6,GADD45G,ARID5A,FLOT1,COX4I1,CDK11B,PITHD1,MRPL19,RRP36,FKBP1A,H2AFY,SLC38A10,UBE3B,IFT46,TMEM160,PHF20L1,ACSL3,SREK1,TTC33,RAB2B,PHF6,CYB5A,ABHD5,PAF1,PFDN5,BRWD1,DUS3L,CERS6,CLK3,BBX,PQBP1,TBPL1,PPA2,CLU,YWHAH,AP2S1,NUDT3 |
| 1.052e-02 | -4.55 | GSE8678_IL7R_LOW_VS_HIGH_EFF_CD8_TCELL_DN | MSigDB lists | GSE8678_IL7R_LOW_VS_HIGH_EFF_CD8_TCELL_DN | 179 | 39 | 17377 | 2626 |
ZNF296,RWDD1,MRI1,TOR1AIP1,ADCK5,NIT2,PIP4K2A,HDDC2,CTSS,IARS,THADA,RABGAP1L,PPIL2,ETV6,ZCCHC2,ORAI1,BCL2,GEMIN4,CSTF1,NEK7,NOA1,PGS1,EMB,PCGF6,MAP4K3,MCFD2,MTR,TSR2,CYB5A,XRCC5,FBXO21,SCARB2,WDR11,PDLIM1,RPL32,TFE3,DTD1,SMAD1,TRAF5 |
| 1.052e-02 | -4.55 | GSE26030_TH1_VS_TH17_DAY15_POST_POLARIZATION_UP | MSigDB lists | GSE26030_TH1_VS_TH17_DAY15_POST_POLARIZATION_UP | 179 | 39 | 17377 | 2626 |
UBE2D3,CMAS,SMAP1,TRIP12,HLA-E,FAM129A,UFC1,RAC1,ANKH,HEXB,SIKE1,FAM8A1,MXD1,PRNP,SUB1,NSRP1,CNPY4,CDKN1B,SLC38A10,TNRC18,CTDSP2,CSNK1G3,PDCL3,FDFT1,PGGT1B,TYW1,ZMYM5,PTTG1IP,PRMT2,GOSR1,SH3GLB1,PLEKHF2,RDH11,HSPB11,FAM3C,CHMP4B,NAA20,ZC3HAV1,TIGD2 |
| 1.052e-02 | -4.55 | GO_CYSTEINE_TYPE_PEPTIDASE_ACTIVITY | MSigDB lists | GO_CYSTEINE_TYPE_PEPTIDASE_ACTIVITY | 179 | 39 | 17377 | 2626 |
OTUD5,USP7,CYLD,ATXN3,CASP6,FAM76A,USP39,USP48,CFLAR,USP5,ATG4A,CAPN2,CTSS,UCHL5,SRI,JOSD1,FAM76B,ZRANB1,SENP1,USP34,TNFAIP3,USP42,USP10,USP22,OTUD3,PEF1,USP21,USP36,ANKZF1,PDCD6,CAPN7,USP32,VCPIP1,USP20,USP11,ESPL1,USP53,CAPN1,USP13 |
| 1.052e-02 | -4.55 | GSE3720_UNSTIM_VS_LPS_STIM_VD1_GAMMADELTA_TCELL_UP | MSigDB lists | GSE3720_UNSTIM_VS_LPS_STIM_VD1_GAMMADELTA_TCELL_UP | 179 | 39 | 17377 | 2626 |
GPR132,GMFG,ANXA6,C5orf30,NOTCH2,MAPK14,SLC20A1,AP3S1,CRLF3,ETS1,RHBDD1,MAD2L2,HLA-A,FBRS,TFAP4,GOLM1,NFATC3,ZNF420,CS,FAM89B,CDKN1B,TTC4,FAM76B,CNOT6L,ILKAP,PGS1,MFNG,PBRM1,ESYT1,MARK2,TWISTNB,ADSS,PPP2R5A,STK38,STK11,DDX5,TCOF1,DCAF5,PDCD4 |
| 1.052e-02 | -4.55 | GSE20715_WT_VS_TLR4_KO_6H_OZONE_LUNG_DN | MSigDB lists | GSE20715_WT_VS_TLR4_KO_6H_OZONE_LUNG_DN | 179 | 39 | 17377 | 2626 |
NAT9,XAB2,WDTC1,LMNA,XPR1,SLC25A36,IRF4,CLUAP1,EXOSC7,UCHL5,PPIG,SSBP3,SEC24C,TNPO3,ANP32A,AQR,IFT46,HTRA2,NUDC,DCTN1,ELOF1,LDHB,RBX1,PPP1R21,JTB,PBRM1,THNSL1,CBFA2T2,HAGH,SF3A2,EIF3G,USP36,POLR2A,UTP20,LRPPRC,APPL2,CHPF2,CBX4,CSNK1D |
| 1.054e-02 | -4.55 | GOT1 (glutamic-oxaloacetic transaminase 1) | protein interactions | 2805 | 59 | 17 | 17029 | 2761 |
PDCD6IP,NQO1,ANXA6,WDR1,RAE1,WDR82,KIF2C,PITPNB,NANS,OAT,GLOD4,SRXN1,PITPNA,MDH1,TALDO1,HTRA2,ANXA11 |
| 1.054e-02 | -4.55 | ZNF707 (zinc finger protein 707) | protein interactions | 286075 | 59 | 17 | 17029 | 2761 |
ZNF445,MRPS2,ZNF316,MRPS26,MRPS10,RPL15,CSNK2A1,TRIM28,ZNF696,ZNF92,DHX57,DAP3,TRIM26,LTBP4,ZNF689,MRPS27,USP34 |
| 1.054e-02 | -4.55 | ASF1A (anti-silencing function 1A histone chaperone) | protein interactions | 25842 | 59 | 17 | 17029 | 2761 |
ANKLE2,NASP,ST13,UBN1,TLK1,CUL1,HTATIP2,MCM2,ASF1B,CHAF1A,TONSL,PML,CABIN1,CHEK2,H3F3A,RBBP4,IPO4 |
| 1.054e-02 | -4.55 | EIF4E (eukaryotic translation initiation factor 4E) | protein interactions | 1977 | 59 | 17 | 17029 | 2761 |
GEMIN5,MKNK1,CYLD,EIF4ENIF1,CSK,AHSA1,PRDM4,PML,NANS,PDXK,EIF4H,ECPAS,EIF4G2,PABPC1,APP,PABPC4,CAPN1 |
| 1.054e-02 | -4.55 | IRS2 (insulin receptor substrate 2) | protein interactions | 8660 | 59 | 17 | 17029 | 2761 |
USP7,EPN1,BCL2L1,SOCS7,UBTF,PTPRF,ATP2A2,JAK1,SHC1,PIK3R2,SOCS6,PTPN11,YWHAZ,BCL2,YWHAH,DVL2,SRPK2 |
| 1.054e-02 | -4.55 | VPS50 (VPS50, EARP/GARPII complex subunit) | protein interactions | 55610 | 59 | 17 | 17029 | 2761 |
SLC39A9,CCDC93,PHF20L1,MAX,GOLIM4,RPRD1A,RCOR1,NUF2,PSMD9,GIT2,HMG20A,SF3B2,OIP5,GRIPAP1,RABGAP1L,SNAP29,ARNTL |
| 1.054e-02 | -4.55 | PHF21A (PHD finger protein 21A) | protein interactions | 51317 | 59 | 17 | 17029 | 2761 |
CCDC93,MAX,RPRD1A,RCOR1,NUF2,PSMD9,HMG20A,GIT2,OIP5,GRIPAP1,RABGAP1L,ARNTL,KIF22,NUP62,RBPJ,NUP58,HDAC2 |
| 1.054e-02 | -4.55 | NAV1 (neuron navigator 1) | protein interactions | 89796 | 59 | 17 | 17029 | 2761 |
ZBTB21,FGFR1OP,MAPRE1,PCM1,NF1,DENND4C,KIF13B,TRIO,PPA2,CDC25B,MAP3K14,MAPK1,PPA1,APP,GCC1,GIGYF1,RTKN |
| 1.056e-02 | -4.55 | LGALS1 (galectin 1) | protein interactions | 3956 | 97 | 25 | 17029 | 2761 |
CYLD,PHB2,RAE1,SNRPB,RAC1,MYH9,PSMG1,S1PR2,MCM2,ICAM2,PCBP1,ARF4,CLNS1A,CDC42,PTEN,MCM5,ITGB1,GEMIN4,LMAN1,TALDO1,IGBP1,HRAS,PCBP2,ANXA11,FUBP1 |
| 1.056e-02 | -4.55 | condensed nuclear chromosome, centromeric region | cellular component | GO:0000780 | 22 | 8 | 18223 | 2701 |
PLK1,DSN1,KMT5C,SS18L1,NUF2,AURKB,CCNB1,MIS12 |
| 1.056e-02 | -4.55 | retromer complex | cellular component | GO:0030904 | 22 | 8 | 18223 | 2701 |
SNX8,SNX27,VPS26B,SNX2,RAB7A,DENND4C,VPS29,DCTN1 |
| 1.056e-02 | -4.55 | U5 snRNP | cellular component | GO:0005682 | 22 | 8 | 18223 | 2701 |
SNRNP200,SNRPB,SNRPG,WDR62,SNRPD3,TXNL4A,PRPF18,DDX23 |
| 1.057e-02 | -4.55 | regulation of DNA replication | biological process | GO:0006275 | 98 | 24 | 17256 | 2622 |
RFC3,CHTF18,CDT1,WDR18,RAC1,DHX9,GTPBP4,DBF4,CDC6,BLM,RFC2,TTF1,WRNIP1,STOML2,PPP2CA,SMC3,PCNA,TIMELESS,CHEK2,ZNF830,CDK2,HRAS,TERF1,TERF2 |
| 1.058e-02 | -4.55 | UBQ | smart domains | SM00213 | 41 | 12 | 9493 | 1367 |
UBQLN4,RPS27A,SUMO2,RAD23B,UHRF2,NFATC2IP,HERPUD2,FAU,UBQLN2,ISG15,UBLCP1,RAD23A |
| 1.061e-02 | -4.55 | DS_RBD | prosite domains | PS50137 | 19 | 7 | 12060 | 1670 |
CDKN2AIP,STAU1,STRBP,PRKRA,DGCR8,ILF3,DHX9 |
| 1.061e-02 | -4.55 | GCM_CHUK | MSigDB lists | GCM_CHUK | 68 | 18 | 17377 | 2626 |
MOB4,DDX47,TOR1AIP1,ALKBH5,TMX3,KLHL18,SUMF2,DCLRE1C,GFM2,SLTM,ABHD16A,RBM25,MTMR4,TBC1D14,CS,CAB39,MTPN,CCAR1 |
| 1.061e-02 | -4.55 | positive regulation of protein dephosphorylation | biological process | GO:0035307 | 39 | 12 | 17256 | 2622 |
CALM2,ANKLE2,TGFB1,PPP2R5A,PPP1R12A,NSMF,PIN1,PPP1R15B,GBA,CDCA2,PPP1R16B,SYMPK |
| 1.061e-02 | -4.55 | protein peptidyl-prolyl isomerization | biological process | GO:0000413 | 39 | 12 | 17256 | 2622 |
PPIF,FKBP1A,PPIB,CWC27,PIN1,PPIG,PPIE,PPIL2,FKBP5,PPWD1,FKBP2,FKBP3 |
| 1.061e-02 | -4.55 | regulation of centrosome duplication | biological process | GO:0010824 | 39 | 12 | 17256 | 2622 |
CHMP2A,PDCD6IP,KAT2A,CENPJ,POC1A,NUP62,XRCC3,CHMP4B,BRCA1,CCNF,CHMP2B,GEN1 |
| 1.062e-02 | -4.54 | MODULE_358 | MSigDB lists | MODULE_358 | 73 | 19 | 17377 | 2626 |
FYTTD1,ORAI2,SNRNP200,KLF10,MIOS,TACC1,NSUN2,DBF4,TRAK1,SEC16A,DHX15,NUP205,CRKL,INTS7,KLHL15,PTPN11,AEN,GLCCI1,NMD3 |
| 1.062e-02 | -4.54 | DACOSTA_UV_RESPONSE_VIA_ERCC3_COMMON_UP | MSigDB lists | DACOSTA_UV_RESPONSE_VIA_ERCC3_COMMON_UP | 73 | 19 | 17377 | 2626 |
SRM,TK1,HLA-E,TMEM109,CDC6,RGS2,FAM8A1,RHOB,NEU1,RNF103,GNS,FGFR3,PCNA,BRD2,ACYP1,CLK3,CLTB,HRAS,TOB1 |
| 1.062e-02 | -4.54 | DER_IFN_ALPHA_RESPONSE_UP | MSigDB lists | DER_IFN_ALPHA_RESPONSE_UP | 73 | 19 | 17377 | 2626 |
PPP3CA,HLA-E,RHOC,TAP1,CYCS,PSMB9,ISG15,HLA-A,FAS,DDX17,ATP6V0B,TRIM26,PML,STAT1,PDXK,RBBP4,SMAD4,TRIM14,IFI16 |
| 1.063e-02 | -4.54 | JUBAN_TARGETS_OF_SPI1_AND_FLI1_UP | MSigDB lists | JUBAN_TARGETS_OF_SPI1_AND_FLI1_UP | 109 | 26 | 17377 | 2626 |
USP7,CHMP2A,FTL,GOLIM4,TRAFD1,ADD1,NEK7,PSPC1,BTG2,GMCL1,WBP1,EZH1,CCDC28A,ZNF804A,PTPRF,VEZF1,CYHR1,ADD3,HIPK2,AHSA1,PHTF1,FUT8,TMEM219,USP11,NRBP1,RNF114 |
| 1.063e-02 | -4.54 | WOOD_EBV_EBNA1_TARGETS_UP | MSigDB lists | WOOD_EBV_EBNA1_TARGETS_UP | 109 | 26 | 17377 | 2626 |
GCLM,MAPRE2,NQO1,ANXA6,CHERP,PRKCSH,SF3B1,UCK2,ILF3,WIPF1,SLC29A1,DNAJB1,NCKAP1,PRKRA,SF3A2,HSPA1B,CALM2,GNAS,FGFR3,SLCO4A1,CCDC6,STAT1,CLU,SCARB1,MAML1,MTX2 |
| 1.063e-02 | -4.54 | RACTNNRTTTNC_UNKNOWN | MSigDB lists | RACTNNRTTTNC_UNKNOWN | 109 | 26 | 17377 | 2626 |
POU2AF1,TSTA3,POC1A,CTCF,SYMPK,STOML2,RDH11,MRPL50,SAP130,RNF121,MKNK1,ZNF420,JAK1,DPYSL2,MRPL34,MRPL54,ANP32E,PCYT2,POLR1B,CITED2,OGG1,PURA,HIGD2A,ZNF189,PRPF19,ABCC5 |
| 1.064e-02 | -4.54 | PUA | smart domains | SM00359 | 4 | 3 | 9493 | 1367 |
NIP7,EIF2D,MCTS1 |
| 1.065e-02 | -4.54 | regulation of apoptotic signaling pathway | biological process | GO:2001233 | 388 | 76 | 17256 | 2622 |
CYLD,TRAF7,IVNS1ABP,NF1,DYNLL1,RAF1,MAGED1,PLAGL2,BCL2L1,BCAP31,PARK7,MOAP1,RRN3,MDM2,SP100,SIAH1,NOC2L,TP53BP2,TMBIM1,HTRA2,BAK1,PGAP2,PPIF,NCK1,VDAC2,MCL1,DNAJA1,BRCA1,PRKRA,SLC25A5,TRIM32,CLU,TFDP2,ARRB2,EYA2,ZC3HC1,MIF,BCL2L12,HSPH1,GCLM,EYA1,PSEN1,APOPT1,LMNA,CFLAR,PTPN2,TFAP4,PTEN,DAPK1,FEM1B,ARHGEF2,BCL2,GNAI2,ATP5IF1,TNFAIP3,RB1CC1,ZMYND11,RFFL,BCLAF1,SYVN1,PTTG1IP,FADD,DAPK3,FAS,HSPA1B,QARS,TFDP1,PPP3R1,PML,E2F1,SIAH2,HMGB2,YWHAZ,YWHAH,TMEM14A,FAF1 |
| 1.069e-02 | -4.54 | GSE4984_UNTREATED_VS_LPS_TREATED_DC_UP | MSigDB lists | GSE4984_UNTREATED_VS_LPS_TREATED_DC_UP | 141 | 32 | 17377 | 2626 |
PPAN,PPP1R9B,ULK3,TIMP2,AATF,TM9SF4,URB2,ZMYM5,KLHL18,CREBL2,MEF2D,RLF,IL21R,SYNRG,TRIM65,HEATR5B,EEF2K,PTPRF,PPP1R3B,SH3BP5,KPNA4,FBXO28,TULP3,ZDHHC13,ZFYVE27,SS18L1,FAU,TOP1MT,MYO9A,MGAT5,MORC3,ZBTB24 |
| 1.071e-02 | -4.54 | Cyclin E associated events during G1/S transition | REACTOME pathways | R-HSA-69202 | 72 | 20 | 10287 | 1696 |
MAX,AKT2,PSMB7,PSMA1,CUL1,PSMB9,PSMD9,PSMB3,PSMC4,PSMD2,RB1,PSMA6,CCNA2,PSMD1,RPS27A,PSMD3,PSMD8,CDKN1B,CDK2,PSMC1 |
| 1.071e-02 | -4.54 | GO_POSITIVE_REGULATION_OF_PROTEIN_MODIFICATION_PROCESS | MSigDB lists | GO_POSITIVE_REGULATION_OF_PROTEIN_MODIFICATION_PROCESS | 1084 | 191 | 17377 | 2626 |
CCNC,TXN,FAM129A,XIAP,CUL1,NENF,CCNL2,S1PR2,CCNB1,MAPK14,PPP1R16B,BIRC2,PARK7,FANCI,FBXO22,CDK5,CALM2,RAP1A,PSMD1,CDC42,IL6ST,FIZ1,FNIP2,CDC25B,DNMT1,MLST8,PLK1,BAK1,COPS8,AKT2,TOPORS,CDC6,BRCA1,DCUN1D5,SOX4,MAP3K4,PAF1,BRMS1,RPS27A,PSMD8,AXIN1,ITGB1,OGT,CAB39,ADAM9,STK11,ZNF268,CHEK2,CLU,DVL1,ARRB2,PSMC1,HDAC2,SVIP,HSPH1,PPP1R12A,CLSPN,GORASP1,PHB2,PHF23,DNAJB2,PRKAA1,GADD45G,CIB1,PSEN1,PSMD9,DDRGK1,FKBP1A,CTR9,BCL2,MDFIC,GNAI2,MAPKAPK3,RB1CC1,GBA,PSMA1,KRAS,RTF1,MAP4K3,ADRB2,PTTG1IP,MAP2K2,PSMB3,PSMC4,MASTL,FAS,DERL1,HSPBP1,FNTA,GOLGA2,CDC27,CSK,RUVBL2,MAP3K5,EHD4,RNF139,ALS2,CDKN2A,TRAF7,RAF1,MAGED1,RAC1,TPX2,CREBL2,DUSP22,PRKACA,LYN,CRKL,TERF2IP,PSMA6,SHC1,RALB,KIF14,MTA1,PIN1,AKAP8,ADCY9,CDKN1B,ANAPC7,MAVS,CHTOP,F2R,ABI1,DVL2,ADCY7,ANKLE2,PSRC1,TIMP2,BIRC3,PSMA8,TAOK1,WBP2,PSMB7,CDCA2,CDC23,RAB1A,TOLLIP,PSMB9,PPP2CA,CDC16,PPP2R5A,TAB2,HIPK2,PSMD3,GADD45B,RPLP1,TICAM1,SMURF1,MAPK1,LRP8,SMAD4,CSNK1D,MIF,ZFP91,FLOT1,PAWR,DCUN1D4,MAD2L2,FBXO5,CCNK,FGFR3,PSMD2,PDCD10,PTEN,AXIN2,PTPN11,ARHGEF2,BRD7,MAP3K14,STAT3,PDPK1,TGFB1,TELO2,ADAM17,RHOA,KAT2A,PRKAR1B,JTB,ANAPC2,ZP3,SYMPK,MARK2,MAPK3,OSBPL8,PML,PKD2,PSAP,UBE2C,CD81,HRAS,ANAPC4 |
| 1.073e-02 | -4.54 | Interactome of polycomb repressive complex 2 (PRC2) | WikiPathways | WP2916 | 17 | 7 | 5312 | 837 |
BCLAF1,THRAP3,EZH1,RBBP4,STK38,SUZ12,MORC3 |
| 1.073e-02 | -4.53 | Tpx2 (TPX2, microtubule-associated) | protein interactions | 72119 | 50 | 15 | 17029 | 2761 |
VEZF1,LUZP1,MYO18A,RPL6,SDC2,SLC27A4,SLC25A12,RACGAP1,COPS7B,SLC38A10,DCUN1D4,BRWD3,CHD1,IPO4,SPTAN1 |
| 1.073e-02 | -4.53 | GATAD1 (GATA zinc finger domain containing 1) | protein interactions | 57798 | 50 | 15 | 17029 | 2761 |
SAP130,BRMS1,FOXK1,MTA2,ZNF335,ATXN1,SS18L1,HERPUD2,RBBP4,TNRC18,SINHCAF,SAP30L,ARID4A,HDAC2,SAP30 |
| 1.073e-02 | -4.53 | SYN1 (synapsin I) | protein interactions | 6853 | 50 | 15 | 17029 | 2761 |
CDK5,SAP130,PSMD2,DGCR8,RB1CC1,LUC7L3,DNAAF2,DDX5,BLM,PRKACA,SRRT,CAMK2G,MAPK3,ATG4A,SPTAN1 |
| 1.073e-02 | -4.53 | Lgals3bp (lectin, galactoside-binding, soluble, 3 binding protein) | protein interactions | 19039 | 50 | 15 | 17029 | 2761 |
MZT2A,MZT1,RAE1,PARP4,CS,OGT,IMPDH1,SDF2L1,SLC26A2,MVP,H3F3A,MZT2B,TUBGCP2,ABHD14A,PCBP2 |
| 1.073e-02 | -4.53 | TCEAL1 (transcription elongation factor A like 1) | protein interactions | 9338 | 50 | 15 | 17029 | 2761 |
DTL,USP7,WDR4,PTPN11,UBE2Q1,CDCA2,C9orf40,USP11,SASS6,MAPK14,STAT3,MCMBP,KDM3A,PPP2R2D,FAF1 |
| 1.075e-02 | -4.53 | negative regulation of apoptotic signaling pathway | biological process | GO:2001234 | 217 | 46 | 17256 | 2622 |
BCL2L12,MIF,HSPH1,GCLM,IVNS1ABP,RAF1,EYA1,BCL2L1,PSEN1,PARK7,LMNA,CFLAR,RRN3,MDM2,NOC2L,DAPK1,ARHGEF2,BCL2,GNAI2,TMBIM1,HTRA2,PGAP2,PPIF,TNFAIP3,RB1CC1,ZMYND11,VDAC2,RFFL,MCL1,SYVN1,DNAJA1,BRCA1,PTTG1IP,SLC25A5,FADD,FAS,HSPA1B,QARS,SIAH2,HMGB2,CLU,TRIM32,TMEM14A,ARRB2,EYA2,ZC3HC1 |
| 1.077e-02 | -4.53 | p53 pathway | Pathway Interaction DB | p53regulationpathway | 59 | 19 | 2226 | 426 |
USP7,CSNK1G2,CSNK1A1,MAPK14,TRIM28,RPL11,PPP2CA,MDM2,CCNA2,HUWE1,KMT5A,CSNK1G1,PIN1,HIPK2,CHEK2,YY1,CDK2,CSNK1G3,CSNK1D |
| 1.079e-02 | -4.53 | KOKKINAKIS_METHIONINE_DEPRIVATION_48HR_UP | MSigDB lists | KOKKINAKIS_METHIONINE_DEPRIVATION_48HR_UP | 125 | 29 | 17377 | 2626 |
ERCC1,TIMP2,BIRC3,CASP6,BTG2,DCTD,BRCA1,CCNB1,MTR,RHOB,FAS,CFLAR,MAT2B,SHC1,PTEN,IL6ST,DUT,TANK,RAD23B,DAPK1,CDKN1B,RNASEL,SMAD1,CDK2,CCNB2,SMAD4,POLQ,SPTAN1,FDFT1 |
| 1.081e-02 | -4.53 | IL-7 Signaling Pathway | WikiPathways | WP205 | 25 | 9 | 5312 | 837 |
JAK1,PIK3R2,STAT1,CDKN1B,BCL2L1,MAPK1,STAT3,MAP2K2,MAPK3 |
| 1.081e-02 | -4.53 | haematopoietic_and_lymphoid_tissue-lymph_node-lymphoid_neoplasm-peripheral_T_cell_lymphoma_unspecified | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-lymph_node-lymphoid_neoplasm-peripheral_T_cell_lymphoma_unspecified | 22 | 8 | 17385 | 2587 |
RB1,KRAS,RHOA,DNMT3A,NRAS,PTEN,HRAS,CDKN2A |
| 1.081e-02 | -4.53 | malignant_melanoma_of_soft_parts-clear_cell_sarcoma | COSMIC cancer mutations | malignant_melanoma_of_soft_parts-clear_cell_sarcoma | 22 | 8 | 17385 | 2587 |
EWSR1,NRAS,PTEN,AXIN1,ETV6,KRAS,HRAS,CDKN2A |
| 1.081e-02 | -4.53 | skin-carcinoma-basal_cell_carcinoma | COSMIC cancer mutations | skin-carcinoma-basal_cell_carcinoma | 22 | 8 | 17385 | 2587 |
FGFR3,NRAS,KRAS,NOTCH2,H3F3A,STAT3,HRAS,CDKN2A |
| 1.081e-02 | -4.53 | upper_aerodigestive_tract-head_neck-carcinoma | COSMIC cancer mutations | upper_aerodigestive_tract-head_neck-carcinoma | 22 | 8 | 17385 | 2587 |
KRAS,NRAS,KMT2C,NF1,SF3B1,SMAD4,CDKN2A,PTPN11 |
| 1.081e-02 | -4.53 | soft_tissue-fibrous_tissue_and_uncertain_origin-sarcoma | COSMIC cancer mutations | soft_tissue-fibrous_tissue_and_uncertain_origin-sarcoma | 22 | 8 | 17385 | 2587 |
NRAS,PTEN,SF3B1,JAZF1,ETV6,KRAS,HRAS,EML4 |
| 1.081e-02 | -4.53 | soft_tissue-fibrous_tissue_and_uncertain_origin-malignant_melanoma_of_soft_parts-clear_cell_sarcoma | COSMIC cancer mutations | soft_tissue-fibrous_tissue_and_uncertain_origin-malignant_melanoma_of_soft_parts-clear_cell_sarcoma | 22 | 8 | 17385 | 2587 |
EWSR1,NRAS,PTEN,AXIN1,ETV6,KRAS,HRAS,CDKN2A |
| 1.082e-02 | -4.53 | AAAYRNCTG_UNKNOWN | MSigDB lists | AAAYRNCTG_UNKNOWN | 338 | 67 | 17377 | 2626 |
ZNF296,GGNBP2,TSC22D3,PLAGL2,BCL2L1,S1PR2,ZADH2,ANKRD28,PHC2,CRKL,MOAP1,TMEM69,TNFAIP8,FIZ1,PDS5B,EIF5,FGFR1OP2,ARID4A,POU2AF1,ZNF524,TRIM8,SLC26A6,LRP5,DIDO1,WBP1,CDC23,RAB5B,TRIM28,MYO18A,NAGLU,TFDP2,MRPL13,ZBTB11,ZMAT3,CAPN1,SCOC,EYA1,ZFP91,NUP54,STRN4,IP6K2,CSNK1A1,POFUT1,NDUFS4,TFAP4,ADD3,KLHL20,CRAT,CAPZA1,TTC17,CITED2,ZNF710,MAML1,PDLIM2,PPP3CA,PPP1R9B,AGGF1,MTA2,PLEC,ARID1A,SEPT7,NCDN,PHF6,NEK1,RUFY3,MAP3K5,DEF6 |
| 1.085e-02 | -4.52 | cytoplasmic side of endoplasmic reticulum membrane | cellular component | GO:0098554 | 14 | 6 | 18223 | 2701 |
PKD2,DNAJA1,THADA,RPS26,SPPL2B,SPPL2A |
| 1.085e-02 | -4.52 | COPII vesicle coat | cellular component | GO:0030127 | 14 | 6 | 18223 | 2701 |
SEC31A,TMED7,PDCD6,PEF1,SAR1A,SEC24C |
| 1.085e-02 | -4.52 | nBAF complex | cellular component | GO:0071565 | 14 | 6 | 18223 | 2701 |
SMARCA4,SS18L1,ARID1A,SMARCE1,ARID1B,SMARCD1 |
| 1.085e-02 | -4.52 | septin filament array | cellular component | GO:0032160 | 14 | 6 | 18223 | 2701 |
SEPT11,TMEM250,SEPT8,SEPT1,SEPT9,SEPT7 |
| 1.085e-02 | -4.52 | nuclear pore central transport channel | cellular component | GO:0044613 | 14 | 6 | 18223 | 2701 |
NUP62,NUP153,NUTF2,NXT1,NXT2,NUP54 |
| 1.085e-02 | -4.52 | septin ring | cellular component | GO:0005940 | 14 | 6 | 18223 | 2701 |
SEPT11,TMEM250,SEPT8,SEPT1,SEPT9,SEPT7 |
| 1.085e-02 | -4.52 | septin complex | cellular component | GO:0031105 | 14 | 6 | 18223 | 2701 |
SEPT11,TMEM250,SEPT8,SEPT1,SEPT9,SEPT7 |
| 1.085e-02 | -4.52 | Endosomal Sorting Complex Required For Transport (ESCRT) | REACTOME pathways | R-HSA-917729 | 28 | 10 | 10287 | 1696 |
CHMP2A,HGS,CHMP4A,RPS27A,CHMP4B,VPS4A,CHMP2B,CHMP7,VPS25,STAM |
| 1.088e-02 | -4.52 | Telomere C-strand (Lagging Strand) Synthesis | REACTOME pathways | R-HSA-174417 | 24 | 9 | 10287 | 1696 |
POLA2,RPA2,PCNA,RFC3,POLE,PRIM2,RFC2,PRIM1,RPA1 |
| 1.088e-02 | -4.52 | GSE45365_WT_VS_IFNAR_KO_CD11B_DC_DN | MSigDB lists | GSE45365_WT_VS_IFNAR_KO_CD11B_DC_DN | 152 | 34 | 17377 | 2626 |
SEPHS2,CCDC93,MAPRE1,AGTRAP,CDCA8,KIF23,HAUS4,KIF2C,B4GALT4,OAT,PSEN1,TMEM165,PRPF18,CALM2,PSMD1,ARF5,KIF14,TIPARP,WDR41,PAQR6,AGGF1,ASPM,RFXANK,ATXN1,TOR1AIP2,BRCA1,RAB1A,ARL5B,ARMC8,CEP55,MAPK6,LMBR1,SIL1,CCNB2 |
| 1.088e-02 | -4.52 | GSE25146_UNSTIM_VS_HELIOBACTER_PYLORI_LPS_STIM_AGS_CELL_DN | MSigDB lists | GSE25146_UNSTIM_VS_HELIOBACTER_PYLORI_LPS_STIM_AGS_CELL_DN | 152 | 34 | 17377 | 2626 |
PRPF38B,ASH1L,GPR132,PNISR,IVNS1ABP,SRSF6,TIA1,CCNL2,CDK11B,CSNK1A1,SLC20A1,SNAPC4,KTN1,RGS1,MED8,PPCDC,SHOC2,BCLAF1,EML4,DDX17,GEMIN5,IDE,JAK1,L3MBTL3,HNRNPR,PPP3R1,NLRC5,OGT,STAT1,PRMT7,DDX5,NCLN,ZC3HAV1,PRPF4B |
| 1.088e-02 | -4.52 | GACTGTT,MIR-212,MIR-132 | MSigDB lists | GACTGTT,MIR-212,MIR-132 | 152 | 34 | 17377 | 2626 |
H2AFZ,ARID2,TSC22D3,MECP2,FKBP2,DAZAP2,FOXO3,NEIL2,PAIP2,PAPOLA,CSDE1,MEX3C,BRI3,ANP32A,FAM76B,SPTSSA,SAP30L,HNRNPM,PHF20L1,BTG2,AMD1,ATXN1,BRCA1,SOX4,FXR1,DHX57,DPYSL3,BRWD1,OSBPL8,PPM1G,H3F3A,MAPK1,FUBP1,PRPF4B |
| 1.091e-02 | -4.52 | RTN4 (reticulon 4) | protein interactions | 57142 | 112 | 28 | 17029 | 2761 |
UNK,SNX2,SNX15,HSDL1,CIRBP,ILF3,TMEM216,ZFYVE21,SIRT2,BCL2L1,KTN1,PLEKHF2,LMNA,RPA1,DERL1,RPA2,HUWE1,ATIC,ARL6IP1,BCL2,ATF2,RTN3,TERF1,POT1,CFL1,DDB1,HNRNPM,EEF1D |
| 1.091e-02 | -4.52 | GSE8685_IL2_STARVED_VS_IL15_ACT_IL2_STARVED_CD4_TCELL_DN | MSigDB lists | GSE8685_IL2_STARVED_VS_IL15_ACT_IL2_STARVED_CD4_TCELL_DN | 196 | 42 | 17377 | 2626 |
TBC1D12,ADAM10,FAM53C,RHOC,MDH2,WDTC1,UCK2,CUL1,RAB6A,IKBIP,TWF2,ANKRD28,GOLM1,COQ4,TTC9C,XRCC2,SLC35B4,NDUFB9,MYBL1,CARM1,TRIM14,EBAG9,PTPN18,CSRP1,CIRBP,TOPORS,ANAPC2,PKMYT1,WDR81,SYMPK,RPL36,TPD52L2,LUC7L3,ADAM9,ROCK1,NCOA1,BTF3,CLN3,ZMIZ1,REEP4,C7orf26,SSRP1 |
| 1.093e-02 | -4.52 | nuclear import signal receptor activity | molecular function | GO:0061608 | 10 | 5 | 17224 | 2647 |
KPNA2,NUTF2,SNUPN,KPNA4,KPNA1 |
| 1.093e-02 | -4.52 | oxidized purine DNA binding | molecular function | GO:0032357 | 10 | 5 | 17224 | 2647 |
BLM,POT1,OGG1,MSH6,MSH2 |
| 1.093e-02 | -4.52 | leucine zipper domain binding | molecular function | GO:0043522 | 10 | 5 | 17224 | 2647 |
PAWR,PMF1,AATF,ERC1,DAPK3 |
| 1.093e-02 | -4.52 | mannosyl-oligosaccharide mannosidase activity | molecular function | GO:0015924 | 10 | 5 | 17224 | 2647 |
MAN2A2,EDEM2,MAN1B1,MAN1A1,USF3 |
| 1.093e-02 | -4.52 | cyclosporin A binding | molecular function | GO:0016018 | 10 | 5 | 17224 | 2647 |
PPIF,PPP3CA,PPIG,PPIE,PPP3R1 |
| 1.095e-02 | -4.51 | glycerophospholipid biosynthetic process | biological process | GO:0046474 | 234 | 49 | 17256 | 2622 |
RAB14,PIGM,CDS2,PIGN,PIGQ,AGPAT1,STARD7,CSNK2A1,AGPAT3,ARF1,CHKB,CDIPT,LCLAT1,RUFY1,PIP4K2A,CPNE3,PIP5K1C,CHKA,FGFR3,PDXP,PYURF,MTMR4,PTEN,PIK3R2,SLC44A1,LPIN2,RAB4A,PTPN11,PIGG,PCYT2,PIKFYVE,LPCAT1,GPD1L,PGAP2,CPNE1,PIGT,DPM1,PGS1,PIP4K2C,MTMR6,MTMR12,TAZ,PI4K2A,ABHD5,MTMR3,AGPAT2,LPCAT4,CHPT1,PTDSS1 |
| 1.096e-02 | -4.51 | NIF3L1 (NGG1 interacting factor 3 like 1) | protein interactions | 60491 | 127 | 31 | 17029 | 2761 |
METTL1,TP53RK,ACP2,MAPRE2,FAM49B,GORASP1,LAP3,DHPS,TACC1,ACTR3,LAMTOR3,KCTD17,DCTD,RANGAP1,AGFG1,CUTC,SH3GLB1,RAD54B,DDX17,PPP2CA,CDKN2C,PFDN5,TPD52L2,NT5DC1,UBXN2B,RBMX,RBM3,STAT3,COIL,RPRD1B,FUBP1 |
| 1.097e-02 | -4.51 | TP53BP2 (tumor protein p53 binding protein 2) | protein interactions | 7159 | 122 | 30 | 17029 | 2761 |
PLK1,HSPH1,POLR2L,PPP1R2,SUMO2,E2F3,BCL2L1,CNTROB,BECN1,APP,WWP2,HOMER1,CEP104,PCM1,HSPA4,SIAH1,CENPJ,E2F4,ODF2,TANK,TXLNA,SIAH2,E2F1,YWHAZ,BCL2,E2F2,YWHAH,SGF29,PARD3,PRPF19 |
| 1.098e-02 | -4.51 | GO_CIS_TRANS_ISOMERASE_ACTIVITY | MSigDB lists | GO_CIS_TRANS_ISOMERASE_ACTIVITY | 44 | 13 | 17377 | 2626 |
FKBP1A,PPIF,PPIB,CWC27,PPIG,PIN1,PPIL2,TTC9C,PPIE,FKBP5,PPWD1,FKBP2,FKBP3 |
| 1.098e-02 | -4.51 | BIOCARTA_TCR_PATHWAY | MSigDB lists | BIOCARTA_TCR_PATHWAY | 44 | 13 | 17377 | 2626 |
CALM2,VAV1,PPP3CA,NFATC3,SHC1,RAF1,RAC1,PTPN7,NFATC2,PPP3CB,ELK1,HRAS,MAPK3 |
| 1.098e-02 | -4.51 | PARK_HSC_MARKERS | MSigDB lists | PARK_HSC_MARKERS | 44 | 13 | 17377 | 2626 |
ASH1L,PCM1,MEA1,ARL6IP1,MCL1,AURKB,RGS2,ZFAND5,ARPC1A,LYN,PARK7,SLC25A39,SSRP1 |
| 1.098e-02 | -4.51 | KEGG_VASOPRESSIN_REGULATED_WATER_REABSORPTION | MSigDB lists | KEGG_VASOPRESSIN_REGULATED_WATER_REABSORPTION | 44 | 13 | 17377 | 2626 |
GNAS,NSF,RAB11B,DYNLL1,DCTN2,ADCY9,ARHGDIB,CREB1,PRKACA,RAB5B,RAB11A,DYNC1LI2,DCTN1 |
| 1.098e-02 | -4.51 | KEGG_NUCLEOTIDE_EXCISION_REPAIR | MSigDB lists | KEGG_NUCLEOTIDE_EXCISION_REPAIR | 44 | 13 | 17377 | 2626 |
RPA2,ERCC1,RFC3,PCNA,POLE,RBX1,XPA,RAD23B,GTF2H2,RFC2,DDB1,RAD23A,RPA1 |
| 1.098e-02 | -4.51 | GO_NEGATIVE_REGULATION_OF_ERBB_SIGNALING_PATHWAY | MSigDB lists | GO_NEGATIVE_REGULATION_OF_ERBB_SIGNALING_PATHWAY | 44 | 13 | 17377 | 2626 |
PTPN2,HGS,CDC42,RPS27A,RAB7A,SOCS4,AP2B1,EPN1,NUP62,PSEN1,AP2S1,STAM,SOCS5 |
| 1.099e-02 | -4.51 | GSE29164_CD8_TCELL_VS_CD8_TCELL_AND_IL12_TREATED_MELANOMA_DAY7_DN | MSigDB lists | GSE29164_CD8_TCELL_VS_CD8_TCELL_AND_IL12_TREATED_MELANOMA_DAY7_DN | 163 | 36 | 17377 | 2626 |
CYTIP,HJURP,SEC61G,SRGN,PTTG1,SLC35B1,CHAC2,NANS,COPB2,MAN1A1,OIP5,RPN1,NUS1,EIF2S2,SLC1A4,IARS,SLC44A1,PPCDC,OSTC,LRRC59,SLC39A9,SEC61B,TK1,ANKRD37,LDHA,MYBL2,RRM2,SSR2,RHOB,MASTL,UAP1,ELMO1,CDCA5,SIL1,PKD2,EHD4 |
| 1.099e-02 | -4.51 | GSE5589_IL6_KO_VS_IL10_KO_LPS_STIM_MACROPHAGE_45MIN_UP | MSigDB lists | GSE5589_IL6_KO_VS_IL10_KO_LPS_STIM_MACROPHAGE_45MIN_UP | 185 | 40 | 17377 | 2626 |
PKP4,GXYLT1,MAGED1,CCM2,CHCHD2,BCL2L1,CRLF3,RAPGEF6,MBD4,WWP2,CCNK,C18orf32,KLHL20,CENPJ,KIF13B,KIFAP3,CNN2,CLN6,TSHZ1,KDM3B,NIPAL3,RPAP3,PPT1,ERLIN1,NOA1,RNPS1,MTMR6,USP22,NEU1,DDX23,TMEM184C,UAP1,STK38,EXOC4,ACAT1,TRIM32,BEND6,MAP3K5,E2F2,HEXA |
| 1.099e-02 | -4.51 | GSE5589_WT_VS_IL6_KO_LPS_STIM_MACROPHAGE_45MIN_DN | MSigDB lists | GSE5589_WT_VS_IL6_KO_LPS_STIM_MACROPHAGE_45MIN_DN | 185 | 40 | 17377 | 2626 |
ZBED3,GCLM,FLYWCH2,SDC2,ARFIP2,SIKE1,CDC42SE2,IL21R,RTKN,IRF4,MBD2,SOCS6,ORAI1,YIF1B,CLDND1,LPCAT1,ABCC1,RBM15B,B3GALT6,NAGPA,LONRF3,LRBA,E2F3,KCNQ1,SF3A2,NCDN,DOT1L,GEMIN5,LEMD2,NUCB1,PFDN4,MAFK,LIMK1,SIAH2,ASNA1,RNF14,GLCCI1,TRAF5,RPS6KC1,ANXA11 |
| 1.099e-02 | -4.51 | GSE2770_IL12_AND_TGFB_VS_IL4_TREATED_ACT_CD4_TCELL_2H_UP | MSigDB lists | GSE2770_IL12_AND_TGFB_VS_IL4_TREATED_ACT_CD4_TCELL_2H_UP | 185 | 40 | 17377 | 2626 |
WSB2,NDUFV2,GCLM,KLHL21,RHOC,DYNLL1,MECP2,ACTR3,TRIO,NANS,ZNF267,ATP6V1B2,HLA-A,NPLOC4,ZER1,RBM23,TNS3,PSMD1,PELO,GMEB1,TXLNA,ZNF200,ZNF189,PTPRK,METTL1,TEX10,CRNKL1,EML4,ABCF1,FADD,PSMC4,CCDC127,C1orf122,HLA-B,KEAP1,EIF4ENIF1,MFAP1,MRPL27,PPP1R11,ATP6V1C1 |
| 1.099e-02 | -4.51 | GSE11864_CSF1_IFNG_VS_CSF1_PAM3CYS_IN_MAC_UP | MSigDB lists | GSE11864_CSF1_IFNG_VS_CSF1_PAM3CYS_IN_MAC_UP | 185 | 40 | 17377 | 2626 |
DDX58,WDYHV1,XPO7,PITHD1,HLA-A,FKBP1A,DECR1,RALB,AP3S2,ATG3,RCSD1,PDS5B,PIK3IP1,TOP1MT,PLCL2,CNPY3,RNLS,WDR41,ADCY7,GINS1,ABHD2,ERMP1,GNG7,LRBA,WIPF1,ATP6V0A1,EIF2AK1,THNSL1,SMAP2,MYO1F,PRIM1,HLA-B,L3MBTL3,QARS,SNAP23,CORO1C,ZNF689,PGRMC1,SLAIN1,OSGEPL1 |
| 1.099e-02 | -4.51 | GSE37301_COMMON_LYMPHOID_PROGENITOR_VS_GRAN_MONO_PROGENITOR_UP | MSigDB lists | GSE37301_COMMON_LYMPHOID_PROGENITOR_VS_GRAN_MONO_PROGENITOR_UP | 185 | 40 | 17377 | 2626 |
MIF,GOLIM4,PHB2,EIF3D,RBM8A,KLHL18,SLC25A44,RGS1,PNO1,DNAJB9,KRR1,PRNP,IRF4,HOMER1,PSMD1,ARHGEF2,POLR1B,PPA1,TXNL1,MAPRE2,MKLN1,RPL8,EZR,TOMM40,METTL22,TTC33,RAB22A,EIF3G,ARF4,GNAS,ALG3,NAP1L1,KPNA1,NIP7,TIMM17A,NFIL3,WDR4,CEBPG,TICAM1,PDCD11 |
| 1.099e-02 | -4.51 | GSE21033_CTRL_VS_POLYIC_STIM_DC_12H_DN | MSigDB lists | GSE21033_CTRL_VS_POLYIC_STIM_DC_12H_DN | 185 | 40 | 17377 | 2626 |
GCLM,KLHL21,GSPT2,TMX4,NUP54,SLC35B1,TMED3,BRIX1,ZNF518A,CHD1,PAIP1,PABPC4,FLAD1,ZNF302,RAB4A,MRPL11,ERI3,CITED2,GPD1L,STRAP,SOCS5,YTHDC1,SP3,IFRD1,MKLN1,TMEM39A,GALC,LDHA,USP10,MRPS10,TTC33,KPNA1,KEAP1,SEL1L,PPP3R1,RBPJ,ATP6V1C1,ESPL1,TERF1,HDAC2 |
| 1.099e-02 | -4.51 | GSE23502_BM_VS_COLON_TUMOR_MYELOID_DERIVED_SUPPRESSOR_CELL_DN | MSigDB lists | GSE23502_BM_VS_COLON_TUMOR_MYELOID_DERIVED_SUPPRESSOR_CELL_DN | 185 | 40 | 17377 | 2626 |
ZNF207,UGP2,DOCK11,RGS2,NCAPG,ARID1B,MBD4,UBLCP1,KRR1,PDS5B,CDKN1B,FAM76B,CHTOP,LDLRAD3,MORC3,MND1,RPRD1A,FOXK1,CELSR2,TLK1,MKI67,RRM2,CDCA2,ARID1A,ADRB2,CADM1,EML4,CBX3,DDX17,SRSF1,HHEX,BRWD1,CCDC14,NEIL3,ZRANB2,HMGB2,TFDP2,FAM208A,ACSF2,PRPF4B |
| 1.099e-02 | -4.51 | GSE17721_0.5H_VS_8H_PAM3CSK4_BMDC_DN | MSigDB lists | GSE17721_0.5H_VS_8H_PAM3CSK4_BMDC_DN | 185 | 40 | 17377 | 2626 |
ABCA3,TXN,CKLF,VTI1A,SIKE1,SLC4A2,EPHX2,ANKIB1,MYEF2,CDC73,UBXN2A,C18orf32,MDM2,TIMM23,CAPZA1,CABLES2,TMX1,CGGBP1,GTPBP4,WBP2,SEPT7,RHOT1,CBFB,TOLLIP,GFER,NEU1,KPNA1,TMEM168,SNAP23,PRDX5,MAPK6,OGT,PPP1R11,SPRYD4,SMAD1,YY1,UBE2C,NRBP1,COIL,PFKP |
| 1.099e-02 | -4.51 | GSE43863_TH1_VS_TFH_EFFECTOR_CD4_TCELL_DN | MSigDB lists | GSE43863_TH1_VS_TFH_EFFECTOR_CD4_TCELL_DN | 185 | 40 | 17377 | 2626 |
MIB2,HECA,GPR132,SF3B1,TMX4,SNX15,HABP4,TRIO,ACAP1,KLF13,MEF2A,CDIPT,CRLF3,TRIM65,PIP5K1C,PAIP2,TNS3,WDR44,ARHGEF1,DNM2,MAP3K14,ZRANB1,CTDSP2,ETV3,LDB1,PARP4,WDR82,RAB3IP,PLEC,ARID1A,RHOT1,KDM3A,STK17B,SLC50A1,BRWD1,WNT5B,RPS14,DCAF11,NCLN,SMAD4 |
| 1.099e-02 | -4.51 | GSE8921_UNSTIM_VS_TLR1_2_STIM_MONOCYTE_12H_DN | MSigDB lists | GSE8921_UNSTIM_VS_TLR1_2_STIM_MONOCYTE_12H_DN | 185 | 40 | 17377 | 2626 |
LYRM4,PHB2,B4GALT5,TAP1,TKT,LETMD1,SMARCA4,IL21R,RSAD1,LYAR,SHC1,TNFAIP8,NDUFB4,TTC4,CEP63,UBE2M,ARL5A,ABCC1,RPL35,SEC61B,RBM42,ETV3,TNFAIP3,HARS,AKT2,RAB7A,WDHD1,PFKFB3,ZDHHC3,EML4,DHX15,EIF3A,RPSA,HLA-B,PCM1,TOMM6,RPS14,NLRC5,VCPIP1,NDE1 |
| 1.099e-02 | -4.51 | GSE46606_IRF4HIGH_VS_WT_CD40L_IL2_IL5_DAY3_STIMULATED_BCELL_UP | MSigDB lists | GSE46606_IRF4HIGH_VS_WT_CD40L_IL2_IL5_DAY3_STIMULATED_BCELL_UP | 185 | 40 | 17377 | 2626 |
CYTIP,MIF4GD,PLXNC1,FOXM1,ANKH,ADCK5,ETS1,RGS1,RPL23A,TERF2IP,CAPN2,ZNF449,IMPAD1,ZNHIT6,ZNF746,PPP6C,SEH1L,PDCL3,RLIM,MOB4,MND1,PSPC1,RDH10,KIF11,KDM3A,RPL27A,APPL1,TWISTNB,OPTN,PAF1,TSC1,PEX5,COX7A2L,CEBPG,UHRF2,MLYCD,CENPT,FBXL3,PDLIM5,YWHAH |
| 1.100e-02 | -4.51 | PWWP | pfam domains | PF00855 | 22 | 8 | 17054 | 2545 |
PWWP2A,PWWP2B,NSD3,DNMT3A,BRPF3,HDGFL2,ZMYND11,MSH6 |
| 1.100e-02 | -4.51 | EIF3H (eukaryotic translation initiation factor 3 subunit H) | protein interactions | 8667 | 78 | 21 | 17029 | 2761 |
UNK,EIF3L,CYLD,TMEM203,GPBP1L1,EIF3D,CSNK2A1,BRCA1,EIF1B,EIF3G,RPS9,EIF3A,WDR48,EIF3K,NAP1L1,ARPC5,TARDBP,CDK2,SMURF1,CD81,PDCD4 |
| 1.100e-02 | -4.51 | FOXE1 (forkhead box E1) | protein interactions | 2304 | 78 | 21 | 17029 | 2761 |
RECQL,MECP2,BTAF1,LDB1,HNRNPUL2,SMARCA4,RANGAP1,DDX39A,SYMPK,ZFR,TFAP4,KPNA1,POLE,CDC27,AKAP8,H2AFY,KIF22,SMPD4,CREB1,ORC3,SMC4 |
| 1.100e-02 | -4.51 | LGALS9 (galectin 9) | protein interactions | 3965 | 78 | 21 | 17029 | 2761 |
SLC12A7,ENPP4,CLCN3,ACP2,ATG9A,PBK,RRAGC,USP39,SLC29A1,MAN2B1,PLXNA1,SLC12A9,ZER1,ATP13A3,NAGLU,PTPN11,ITGB1,PDIA6,SLC12A2,C2CD5,PTPRK |
| 1.104e-02 | -4.51 | Intra-Golgi traffic | REACTOME pathways | R-HSA-6811438 | 45 | 14 | 10287 | 1696 |
MAN2A2,NAPG,CYTH1,GOLIM4,NSF,SNAP29,VPS45,VTI1A,COG1,ARF1,STX16,GOSR1,RIC1,MAN1A1 |
| 1.104e-02 | -4.51 | ATG4C (autophagy related 4C cysteine peptidase) | protein interactions | 84938 | 13 | 6 | 17029 | 2761 |
PSMD2,USP11,PSMC1,PRKDC,RAB3IL1,PSMC4 |
| 1.104e-02 | -4.51 | MNDA (myeloid cell nuclear differentiation antigen) | protein interactions | 4332 | 13 | 6 | 17029 | 2761 |
PRMT7,KRAS,RB1,NSD3,CDK2,STAT3 |
| 1.104e-02 | -4.51 | ACSF2 (acyl-CoA synthetase family member 2) | protein interactions | 80221 | 13 | 6 | 17029 | 2761 |
WDR44,AGTRAP,GNB2,PPA2,MRPL12,ARL6IP1 |
| 1.104e-02 | -4.51 | SFMBT1 (Scm like with four mbt domains 1) | protein interactions | 51460 | 13 | 6 | 17029 | 2761 |
PSMA1,PHC2,KIF22,RBPJ,ZCCHC10,HMG20A |
| 1.104e-02 | -4.51 | Gpkow (G patch domain and KOW motifs) | protein interactions | 209416 | 13 | 6 | 17029 | 2761 |
USP7,APLP2,BUD13,NDE1,DHX16,YJU2 |
| 1.104e-02 | -4.51 | BST2 (bone marrow stromal cell antigen 2) | protein interactions | 684 | 13 | 6 | 17029 | 2761 |
CHMP4B,HGS,CAPZA2,HAGH,TAB2,TFRC |
| 1.104e-02 | -4.51 | UBN1 (ubinuclein 1) | protein interactions | 29855 | 13 | 6 | 17029 | 2761 |
CABIN1,H3F3A,POLR2A,ASF1B,MASTL,CDC5L |
| 1.104e-02 | -4.51 | BRWD1 (bromodomain and WD repeat domain containing 1) | protein interactions | 54014 | 13 | 6 | 17029 | 2761 |
SMARCA4,STAT3,APP,APPL1,DDB1,CUL3 |
| 1.104e-02 | -4.51 | FBXO42 (F-box protein 42) | protein interactions | 54455 | 13 | 6 | 17029 | 2761 |
CUL1,RBPJ,COPS6,RBX1,SMURF1,CCDC6 |
| 1.104e-02 | -4.51 | SCO1 (SCO1, cytochrome c oxidase assembly protein) | protein interactions | 6341 | 13 | 6 | 17029 | 2761 |
NDUFA4,MTMR12,SYNCRIP,EYA2,NDUFS7,LRPPRC |
| 1.104e-02 | -4.51 | TRAK1 (trafficking kinesin protein 1) | protein interactions | 22906 | 13 | 6 | 17029 | 2761 |
KIF5B,HGS,POLR2A,TRAK1,CDC5L,OGT |
| 1.104e-02 | -4.51 | Sept2 (septin 2) | protein interactions | 18000 | 13 | 6 | 17029 | 2761 |
SEPT8,SEPT11,SDF2L1,SEPT7,SEPT9,MAT2A |
| 1.104e-02 | -4.51 | Sept7 (septin 7) | protein interactions | 235072 | 13 | 6 | 17029 | 2761 |
SEPT8,SEPT11,MKNK1,SEPT9,CXXC1,CPEB2 |
| 1.104e-02 | -4.51 | Ptbp1 (polypyrimidine tract binding protein 1) | protein interactions | 19205 | 13 | 6 | 17029 | 2761 |
IVNS1ABP,MATR3,NSUN4,HNRNPM,SUGP2,RAVER2 |
| 1.104e-02 | -4.51 | Smarcc1 (SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1) | protein interactions | 20588 | 13 | 6 | 17029 | 2761 |
SMARCA4,ARID1A,SMARCE1,ARID2,SMARCD1,NSFL1C |
| 1.104e-02 | -4.51 | Apoptosis - multiple species | KEGG pathways | hsa04215 | 33 | 11 | 7161 | 1149 |
BAK1,BIRC3,BIRC5,XIAP,BCL2,CYCS,BCL2L1,BECN1,BIRC2,HTRA2,FADD |
| 1.104e-02 | -4.51 | Apoptosis - multiple species | KEGG pathways | ko04215 | 33 | 11 | 7161 | 1149 |
BAK1,BIRC3,BIRC5,XIAP,BCL2,CYCS,BCL2L1,BECN1,BIRC2,HTRA2,FADD |
| 1.105e-02 | -4.51 | HOLLMANN_APOPTOSIS_VIA_CD40_DN | MSigDB lists | HOLLMANN_APOPTOSIS_VIA_CD40_DN | 241 | 50 | 17377 | 2626 |
USP7,DNMT3A,PARP12,GMFG,CASP6,GNPDA1,KLHL21,HLA-E,TOR1AIP1,NIT2,NOTCH2,BZW2,DECR1,RPN1,SUB1,HOMER1,ZNF302,RRBP1,CDKN1B,ANXA5,SEPT11,SUCLG2,TAP2,TFG,SMARCE1,NAA35,EEF1D,TMX1,RPP25,PPP3CA,TSTA3,CREG1,CPOX,RPL8,CHMP2B,GOSR1,PSMB9,TARS,ANKRD10,HLA-B,PON2,SEC23IP,PDLIM1,CERS6,STAT1,PPA2,LY75,ZNF45,ZC3HAV1,TMEM131 |
| 1.106e-02 | -4.50 | adrenal_cortical_hyperplasia | COSMIC cancer mutations | adrenal_cortical_hyperplasia | 14 | 6 | 17385 | 2587 |
GNAS,KRAS,ATP1A1,NRAS,MEN1,HRAS |
| 1.106e-02 | -4.50 | penis | COSMIC cancer mutations | penis | 14 | 6 | 17385 | 2587 |
KRAS,STK11,NRAS,PTEN,HRAS,CDKN2A |
| 1.106e-02 | -4.50 | GO_SPLICEOSOMAL_TRI_SNRNP_COMPLEX | MSigDB lists | GO_SPLICEOSOMAL_TRI_SNRNP_COMPLEX | 26 | 9 | 17377 | 2626 |
SART1,LSM6,SNRPB,PRPF4,SNRPG,PRPF3,SNRPD3,TXNL4A,PRPF18 |
| 1.106e-02 | -4.50 | MODULE_333 | MSigDB lists | MODULE_333 | 26 | 9 | 17377 | 2626 |
MIF4GD,ACP2,ZNF559,CELSR2,EPHX2,CHCHD6,ZC3H3,GCSH,HMGN2 |
| 1.106e-02 | -4.50 | GO_SOMATIC_DIVERSIFICATION_OF_IMMUNOGLOBULINS | MSigDB lists | GO_SOMATIC_DIVERSIFICATION_OF_IMMUNOGLOBULINS | 26 | 9 | 17377 | 2626 |
ERCC1,EXOSC6,CTNNBL1,PRKDC,TCF3,PMS2,MSH2,MSH6,POLQ |
| 1.106e-02 | -4.50 | GO_PROTEIN_K11_LINKED_UBIQUITINATION | MSigDB lists | GO_PROTEIN_K11_LINKED_UBIQUITINATION | 26 | 9 | 17377 | 2626 |
UBE2D3,UBE2E2,CDC16,CDC27,ANAPC7,ANAPC2,CDC23,UBE2C,ANAPC4 |
| 1.106e-02 | -4.50 | GO_ACYLGLYCEROL_O_ACYLTRANSFERASE_ACTIVITY | MSigDB lists | GO_ACYLGLYCEROL_O_ACYLTRANSFERASE_ACTIVITY | 26 | 9 | 17377 | 2626 |
AGPAT2,LPCAT4,AGPAT1,MBOAT1,AGPAT3,LCLAT1,TAZ,LPCAT1,ABHD5 |
| 1.106e-02 | -4.50 | GO_REGULATION_OF_CELL_CYCLE_CHECKPOINT | MSigDB lists | GO_REGULATION_OF_CELL_CYCLE_CHECKPOINT | 26 | 9 | 17377 | 2626 |
RFWD3,RPA2,BRD4,THOC1,FEM1B,XRCC3,CHEK2,CCNB1,GEN1 |
| 1.106e-02 | -4.50 | GO_REGULATION_OF_ACTIN_NUCLEATION | MSigDB lists | GO_REGULATION_OF_ACTIN_NUCLEATION | 26 | 9 | 17377 | 2626 |
CYFIP1,WAS,GMFG,GMFB,ARFIP2,WIPF1,NCKAP1,ARF1,CORO1A |
| 1.106e-02 | -4.50 | KEGG_HOMOLOGOUS_RECOMBINATION | MSigDB lists | KEGG_HOMOLOGOUS_RECOMBINATION | 26 | 9 | 17377 | 2626 |
RPA2,RAD51C,XRCC2,TOP3A,XRCC3,BLM,RAD51D,RAD54B,RPA1 |
| 1.106e-02 | -4.50 | negative regulation of transcription by RNA polymerase II | biological process | GO:0000122 | 805 | 146 | 17256 | 2622 |
TXN,ZNF496,MAX,TSC22D3,SIRT2,UBE2I,CREM,GLIS2,JAZF1,ETV6,NOC2L,CRY2,FNIP2,DNMT1,RYBP,PLK1,PLK3,SP3,DEAF1,KLF10,NCK1,GABPA,VHL,EHMT1,RIOX2,DDX20,EZR,AURKB,PAF1,BRMS1,HHEX,SMAD2,RPS27A,RPS14,AXIN1,ZNF268,BEND6,HDAC2,ZNF564,UBE2D3,CTCF,MEF2A,DNAJB1,PSEN1,CDC73,LYAR,RB1,MLX,NFATC3,KLF16,MBD2,HDAC7,PHF14,ZNF746,CTR9,TIMELESS,YBX1,MCPH1,ZNF189,ETV3,CIC,MTA2,LDB1,RTF1,ARID1A,CBFA2T2,PHF6,ZNF174,ETS2,NFIL3,ZFP90,YY1,CDK2,N4BP2L2,MBD1,ZNF296,DNMT3A,FOXM1,SUZ12,WDTC1,SMARCA4,IRF3,DUSP22,RCOR3,MXD1,HNRNPA2B1,SAP130,MDM2,SP100,ATF2,STRAP,CGGBP1,SAP30,MOSPD1,RLIM,ZNF500,ERF,EID1,DRAP1,BTG2,CUL3,PCGF6,NFATC2,MBD3,TRIM28,CHCHD3,RBL1,STAT6,HIPK2,MAFK,DNAJC17,STAT1,BEND3,SMAD4,LRP8,CBX4,NCOR2,MECP2,TCF3,ARID5A,PAWR,MXD4,FOXO3,HMG20A,MAD2L2,WWP2,PTPN2,SUV39H2,KMT5A,H2AFY,CITED2,STAT3,NCOA2,TGFB1,TSHZ1,ZNF202,RCOR1,MEN1,GPS2,ZHX1,E2F1,DDX5,RBPJ,NR2F2,IGBP1,IFI16 |
| 1.106e-02 | -4.50 | KEGG_PATHWAYS_IN_CANCER | MSigDB lists | KEGG_PATHWAYS_IN_CANCER | 321 | 64 | 17377 | 2626 |
MAX,RAF1,RAC1,SLC2A1,XIAP,BCL2L1,BIRC2,CRKL,MDM2,CDC42,RALB,PIK3R2,CDKN1B,TFG,DVL2,NRAS,BIRC3,RBX1,AKT2,VHL,E2F3,SMAD2,JAK1,AXIN1,STAT1,ITGB1,DVL1,E2F2,MAPK1,TRAF5,SMAD4,HDAC2,CYCS,ETS1,FZD6,FGFR3,RB1,PTEN,AXIN2,MSH2,DAPK1,BCL2,STAT3,MSH6,TGFB1,RHOA,KRAS,APPL1,MAP2K2,DAPK3,FADD,FAS,RXRB,MAPK3,CCDC6,BIRC5,WNT5B,PIAS2,E2F1,PML,CDK2,HRAS,CDKN2A,EGLN1 |
| 1.109e-02 | -4.50 | positive regulation of nuclear division | biological process | GO:0051785 | 63 | 17 | 17256 | 2622 |
TGFB1,PHB2,CDT1,CUL3,NUSAP1,LRP5,SIRT2,BECN1,RB1,NSMCE2,CDCA5,H2AFY,NUP62,UBE2C,SLF1,SLF2,ESPL1 |
| 1.111e-02 | -4.50 | Amyotrophic lateral sclerosis (ALS) | WikiPathways | WP2447 | 38 | 12 | 5312 | 837 |
CAT,DERL1,PPP3CA,RAC1,BCL2,BCL2L1,PPP3CB,TOMM40,MAP3K5,MAPK14,MAP2K2,ALS2 |
| 1.113e-02 | -4.50 | MORF_RAP1A | MSigDB lists | MORF_RAP1A | 136 | 31 | 17377 | 2626 |
PHF10,PRIM2,ZNF500,HMGN4,POLR2K,SLC2A1,KLHL18,NKRF,BMS1,CDK13,BRCA1,CCNF,PCGF1,MFN2,SEC31A,TAF2,RB1,RAP1A,SEC23IP,TBC1D22A,CHD3,DCK,TPP2,ATP6V0A2,GTSE1,ZBTB22,TAF5L,PPP5C,CPSF4,CAMK2G,NUMB |
| 1.113e-02 | -4.50 | TK1 (thymidine kinase 1) | protein interactions | 7083 | 173 | 40 | 17029 | 2761 |
IMMT,RPS2,ATXN3,ADD1,TSC2,HMGXB3,PM20D2,ATP5F1B,EXT2,APP,HERC3,FLAD1,KLHL5,MSH2,HADHB,DUS2,UPF2,MAST2,PTPRK,DEAF1,TK1,TCTEX1D2,DRAP1,ZNF202,WDR18,MKI67,PKM,ODC1,EIF3G,NMT2,RPA1,PLD3,QARS,KMT2B,ACTB,ASNA1,COPS6,RBBP4,NRBP1,FAF1 |
| 1.116e-02 | -4.50 | pheochromocytoma | COSMIC cancer mutations | pheochromocytoma | 326 | 64 | 17385 | 2587 |
RHOG,PRPF38B,MAX,PNISR,NPHP4,ZCCHC8,PHF23,NF1,MRPL39,ANK3,SMARCA4,ZNF107,EIF2AK4,ZADH2,SDHA,FAM8A1,GNB2,NUP205,CDKN2C,FGFR3,RB1,PTEN,RAD23B,NSFL1C,PTPN11,DCP1A,CTR9,NAP1L4,APOOL,ZRANB1,STAT3,RNLS,ZNF189,PTPRK,TSHZ1,CNTN5,NRAS,SEPT9,PPT1,VHL,KRAS,KCNQ1,CAPZA2,KMT2C,MEN1,MPG,ZNF407,GNAS,AHNAK,FNTA,PALB2,DGCR8,PRPS2,STK11,CTSA,WIPI2,AKNA,ZNF598,ABCA1,TERF1,SMAD4,HRAS,CDKN2A,PFKP |
| 1.120e-02 | -4.49 | PWWP_dom | interpro domains | IPR000313 | 22 | 8 | 18492 | 2768 |
PWWP2A,PWWP2B,DNMT3A,BRPF3,ZMYND11,NSD3,HDGFL2,MSH6 |
| 1.120e-02 | -4.49 | G_patch_dom | interpro domains | IPR000467 | 22 | 8 | 18492 | 2768 |
GPATCH1,RBM17,SUGP1,NKRF,AGGF1,CHERP,SUGP2,GPATCH4 |
| 1.120e-02 | -4.49 | antigen processing and presentation of exogenous peptide antigen via MHC class I | biological process | GO:0042590 | 78 | 20 | 17256 | 2622 |
PSMA8,HLA-E,TAP1,PSMB7,PSMA1,ITGB5,PSMB9,PSMD9,PSMB3,HLA-A,PSMC4,HLA-B,PSMD2,PSMD1,PSMA6,PSMD8,SNAP23,PSMD3,TAP2,PSMC1 |
| 1.120e-02 | -4.49 | PCP/CE pathway | REACTOME pathways | R-HSA-4086400 | 96 | 25 | 10287 | 1696 |
RHOA,PSMA8,RAC1,PSMB7,PSMA1,PSMD9,PSMB9,PSMB3,FZD6,PSMC4,PSMD2,PSMA6,PSMD1,RPS27A,PSMD8,WNT5B,PSMD3,AP2B1,DVL1,CLTB,ARRB2,SMURF1,PSMC1,AP2S1,DVL2 |
| 1.121e-02 | -4.49 | GO_VESICLE_MEMBRANE | MSigDB lists | GO_VESICLE_MEMBRANE | 491 | 93 | 17377 | 2626 |
EXOC3,ANKRD27,TMED7,RAB14,ABCA3,COPA,RAB11B,ZDHHC8,COPE,SNX15,AP3M2,VTI1A,BCL2L1,AP1B1,SYNRG,APLP2,ATP6V0B,RAB21,RAB8A,MDM2,ATP2A2,AP3S2,SRI,DNM2,AP1M1,AP2B1,CORO1A,CYB5R1,CLTB,LMAN1,CLCN3,USO1,NCK1,GOPC,RAB7A,SLC26A6,ATP6V0A1,SLC17A5,MCFD2,RAB22A,NECAP2,CHMP4A,WAS,TMED10,SCAP,RPS27A,AP1S1,ATP6V0C,SCARB1,AP2S1,ATP6V0E1,DNAJC5,AGTRAP,HLA-E,SCYL1,RAB23,TMX3,TMED3,AP3S1,RAB11A,COPG2,MFSD10,COPB2,FZD6,HLA-A,SPPL2A,CD59,CLIC4,SNX18,ZNRF2,SEC24C,ZDHHC13,ATP6V0A2,PIKFYVE,ATP6V0D1,TMED2,CAMK2G,KDELR1,VOPP1,DENND4C,KCNQ1,ZP3,APPL1,PICALM,SPPL2B,PI4K2A,SEC31A,HLA-B,SEC23IP,WNT5B,YWHAZ,YWHAH,SNAPIN |
| 1.121e-02 | -4.49 | zf-UBP | pfam domains | PF02148 | 14 | 6 | 17054 | 2545 |
USP20,BRAP,USP39,USP22,USP5,USP13 |
| 1.124e-02 | -4.49 | CAPNS1 (calpain small subunit 1) | protein interactions | 826 | 64 | 18 | 17029 | 2761 |
AGTRAP,CAST,ADRB2,ATP5MF,RAB1A,GNB2,TUBGCP2,MAT2A,MAT2B,CAPN2,HUWE1,YWHAZ,EIF5,STAT3,YWHAH,TRAF5,TERF1,CAPN1 |
| 1.124e-02 | -4.49 | S100A4 (S100 calcium binding protein A4) | protein interactions | 6275 | 64 | 18 | 17029 | 2761 |
UNK,CORO7,RHOA,UQCR10,KAT7,DYNLL1,XIAP,PSMA1,MYH9,SEPT7,SMAD2,MDM2,BBX,H2AFX,IGBP1,CDK2,S100A6,SRPK2 |
| 1.124e-02 | -4.49 | GTF2H1 (general transcription factor IIH subunit 1) | protein interactions | 2965 | 64 | 18 | 17029 | 2761 |
POU2AF1,ERCC1,MCM2,REEP5,POLR2A,RPA1,GTF2F1,RXRB,RAD23A,RPA2,RB1,RAD23B,XPA,E2F1,TCEA1,GTF2H2,FUBP1,NUDC |
| 1.124e-02 | -4.49 | RIF1 (replication timing regulatory factor 1) | protein interactions | 55183 | 64 | 18 | 17029 | 2761 |
SLC39A9,SUCLG1,PPT1,HPDL,TOR1AIP1,GNE,PABPC4,ASF1B,LMNA,TERF2IP,MRPL50,CHD3,BRD7,CLN3,PITRM1,POT1,CDC5L,SMARCD1 |
| 1.124e-02 | -4.49 | CPSF1 (cleavage and polyadenylation specific factor 1) | protein interactions | 29894 | 64 | 18 | 17029 | 2761 |
STAU1,PRRC2A,CUL3,RANGAP1,MCM2,SYMPK,CDC73,POLR2A,RPA1,PAPOLA,RPA2,MED8,GLIS2,CHD3,TARDBP,TAF12,CPSF4,COPS6 |
| 1.126e-02 | -4.49 | NDUFB7 (NADH:ubiquinone oxidoreductase subunit B7) | protein interactions | 4713 | 37 | 12 | 17029 | 2761 |
NDUFA2,PHB2,RAB7A,LAMTOR3,MPV17,NDUFB9,NDUFA4,COX4I1,NDUFS5,ATP6V0D1,NDUFS7,CAPN1 |
| 1.126e-02 | -4.49 | ABI3 (ABI family member 3) | protein interactions | 51225 | 37 | 12 | 17029 | 2761 |
WASF2,FARSA,HOMER1,VASP,WAS,SNAP23,PSMA1,MRFAP1L1,TMEM147,CYFIP2,NUP58,EIF3H |
| 1.126e-02 | -4.49 | VPS36 (vacuolar protein sorting 36 homolog) | protein interactions | 51028 | 37 | 12 | 17029 | 2761 |
NXT1,SNX15,TTC4,UBE4B,SRSF5,PPP3CB,TWF2,ECPAS,VPS25,VPS29,KDELR1,CDC5L |
| 1.126e-02 | -4.49 | FES (FES proto-oncogene, tyrosine kinase) | protein interactions | 2242 | 37 | 12 | 17029 | 2761 |
HSPA4,JAK1,ZNF746,FKBP5,PTGES3,PLXNA1,SMURF1,STAT3,POT1,TRIM28,TERF1,APP |
| 1.126e-02 | -4.49 | KNSTRN (kinetochore localized astrin (SPAG5) binding protein) | protein interactions | 90417 | 37 | 12 | 17029 | 2761 |
MAPRE1,PCM1,TACC1,DYNLL1,MAPK6,KIF22,COPS7B,CLU,SGF29,SSSCA1,DCTN1,PRPF19 |
| 1.126e-02 | -4.49 | ATP1A3 (ATPase Na+/K+ transporting subunit alpha 3) | protein interactions | 478 | 37 | 12 | 17029 | 2761 |
HLA-B,ERGIC3,VDAC2,ATXN1,SLC25A22,TGOLN2,CRY2,VPS4A,VDAC1,RAB1A,SPPL2B,ATP6V0D1 |
| 1.126e-02 | -4.49 | HACD3 (3-hydroxyacyl-CoA dehydratase 3) | protein interactions | 51495 | 37 | 12 | 17029 | 2761 |
STAU1,NEK6,ATP2A2,PELO,RAC1,CUL3,CLN3,CHCHD6,BZW2,FANCI,IFI16,CAND1 |
| 1.126e-02 | -4.49 | HBS1L (HBS1 like translational GTPase) | protein interactions | 10767 | 37 | 12 | 17029 | 2761 |
LIN9,EXOSC6,EXOSC7,PELO,EXOSC1,CUL3,JMJD6,EXOSC9,LYN,APP,FANCI,SRPK2 |
| 1.126e-02 | -4.49 | FAM192A (family with sequence similarity 192 member A) | protein interactions | 80011 | 37 | 12 | 17029 | 2761 |
EWSR1,CLK3,PSMA1,CCDC69,RPL15,KIFAP3,CREB1,BLM,YWHAH,PSMB9,LMNA,PSMB3 |
| 1.126e-02 | -4.49 | Naa10 (N(alpha)-acetyltransferase 10, NatA catalytic subunit) | protein interactions | 56292 | 37 | 12 | 17029 | 2761 |
PNISR,INTS7,KIF14,PRDX5,TTC9C,NAA50,DNM2,MYO9A,ARRB2,C2CD5,SF3A2,CHAF1A |
| 1.126e-02 | -4.49 | PPP2R5A (protein phosphatase 2 regulatory subunit B'alpha) | protein interactions | 5525 | 37 | 12 | 17029 | 2761 |
PPP2CA,NEK1,SHC1,CDC27,AXIN1,PTTG1,DAPK1,BCL2,CHEK2,CSNK1A1,ESPL1,PPP2R2D |
| 1.126e-02 | -4.49 | NHP2 (NHP2 ribonucleoprotein) | protein interactions | 55651 | 37 | 12 | 17029 | 2761 |
NOL12,COX15,SUZ12,JMJD6,TCOF1,FBL,GAR1,IFI16,WDR48,LMNA,PRNP,CAND1 |
| 1.127e-02 | -4.49 | Signaling by TGF-beta Receptor Complex | REACTOME pathways | R-HSA-170834 | 77 | 21 | 10287 | 1696 |
TGFB1,UBE2D3,CCNC,NCOR2,RHOA,MEN1,CCNK,FKBP1A,SMAD2,RPS27A,MTMR4,RBL1,UCHL5,E2F4,TFDP1,TFDP2,SMURF1,SMAD4,UBE2M,STRAP,PARD3 |
| 1.128e-02 | -4.48 | soft_tissue-blood_vessel-haemangioma | COSMIC cancer mutations | soft_tissue-blood_vessel-haemangioma | 18 | 7 | 17385 | 2587 |
TSC1,KRAS,EWSR1,NRAS,TSC2,PTEN,HRAS |
| 1.128e-02 | -4.48 | dysplasia | COSMIC cancer mutations | dysplasia | 18 | 7 | 17385 | 2587 |
GNAS,KRAS,NRAS,PTEN,SF3B1,HRAS,CDKN2A |
| 1.128e-02 | -4.48 | salivary_gland-carcinoma-acinic_cell_carcinoma | COSMIC cancer mutations | salivary_gland-carcinoma-acinic_cell_carcinoma | 18 | 7 | 17385 | 2587 |
KRAS,STK11,NRAS,PTEN,HRAS,SMAD4,ETV6 |
| 1.128e-02 | -4.48 | salivary_duct_carcinoma | COSMIC cancer mutations | salivary_duct_carcinoma | 18 | 7 | 17385 | 2587 |
KRAS,STK11,NRAS,PTEN,HRAS,SMAD4,CDKN2A |
| 1.130e-02 | -4.48 | V$NERF_Q2 | MSigDB lists | V$NERF_Q2 | 230 | 48 | 17377 | 2626 |
TCF12,GGNBP2,GPR132,ZNF768,ACTR3,VPS45,CDCA3,AGPAT1,KLF13,SLC4A2,SECISBP2,LANCL1,LYN,TFRC,USP5,MCTS1,FBRS,CDK5,NFATC3,UCHL5,CAPZA1,CORO1A,ZNF800,LYPLA2,EBAG9,ELOVL5,PPP1R9B,BAZ2A,GMFB,TOPORS,ARHGDIB,FOXRED1,MAPK3,IWS1,C1orf122,HMGN2,EIF3K,UBTF,ATP1A1,GOLGA7,FAM110A,TPP2,ARAP1,UQCRH,NCLN,ARRB2,ZMAT3,DEF6 |
| 1.130e-02 | -4.48 | V$E2F1_Q3_01 | MSigDB lists | V$E2F1_Q3_01 | 230 | 48 | 17377 | 2626 |
ANKRD13D,PHF23,GGA1,RMI2,KLF13,FKBP2,S1PR2,STMN1,FOXO3,GNB2,XPR1,RAD23A,PSMD2,AHCTF1,INTS7,FUT8,AXIN2,TNPO3,TTC17,MAML1,EIF5,MCMBP,DNMT1,CGGBP1,EIF5A,CLPTM1,YTHDC1,KLF10,C16orf72,LNX2,FBXO9,ATXN1,DNAJC9,ARHGEF12,CADM1,HMGN2,PRIM1,ATAD2,SYNCRIP,RBL1,DCK,ZNF367,ARNTL,UHRF2,E2F1,NR2F2,LRP8,ADAM23 |
| 1.131e-02 | -4.48 | Hexose transport | REACTOME pathways | R-HSA-189200 | 54 | 16 | 10287 | 1696 |
NDC1,NUP188,RAE1,SLC2A1,NUP54,NUP155,SLC50A1,NUP205,NUP210,NUP107,NUP153,NUP62,NUP85,NUP58,SEH1L,AAAS |
| 1.136e-02 | -4.48 | PFDN2 (prefoldin subunit 2) | protein interactions | 5202 | 83 | 22 | 17029 | 2761 |
RPAP3,PRKAB1,CDC40,EWSR1,POC1A,UBQLN2,MCM2,SEC16A,STMN1,CLNS1A,DTL,RPA2,RFWD3,PFDN5,TPD52L2,HINT1,PFDN4,PDRG1,RUVBL2,PPP6R2,IGBP1,PPP6R1 |
| 1.136e-02 | -4.48 | GEMIN4 (gem nuclear organelle associated protein 4) | protein interactions | 50628 | 83 | 22 | 17029 | 2761 |
KARS,SNRPB,AGO2,DHX9,RNPS1,DDX20,GAR1,PARK7,SRRT,RPA1,GEMIN5,FLAD1,RPA2,GEMIN6,GEMIN4,SNRPG,FBL,CLN3,SNRNP70,STRAP,GEMIN7,CDC5L |
| 1.138e-02 | -4.48 | Znf_UBP | interpro domains | IPR001607 | 14 | 6 | 18492 | 2768 |
BRAP,USP39,USP20,USP22,USP5,USP13 |
| 1.142e-02 | -4.47 | integral component of Golgi membrane | cellular component | GO:0030173 | 45 | 13 | 18223 | 2701 |
YIF1A,GALNT2,SYS1,SLC35B4,SLC39A13,MFNG,TPST1,PCSK7,YIF1B,SAMD8,SLC35B1,SLC35B2,QSOX2 |
| 1.145e-02 | -4.47 | GSE27786_CD4_TCELL_VS_MONO_MAC_DN | MSigDB lists | GSE27786_CD4_TCELL_VS_MONO_MAC_DN | 191 | 41 | 17377 | 2626 |
C9orf78,MAPRE1,TXN,HJURP,TM9SF4,AGTRAP,POC1A,FAM129A,ARF1,TMEM179B,VASP,COQ4,RALB,LRRC8D,PPP4R1,CENPM,TECR,TMEM8A,FBXL19,HTRA2,SAP30,PTPRK,PHF10,NCK1,CREG1,RABIF,MAP7D1,BRCA1,BORA,API5,PWWP2B,RAD51C,RBL1,HIPK2,STK11,GPI,SASS6,CDK2,YWHAH,ARHGAP23,TSPAN5 |
| 1.145e-02 | -4.47 | GSE17721_CTRL_VS_PAM3CSK4_12H_BMDC_DN | MSigDB lists | GSE17721_CTRL_VS_PAM3CSK4_12H_BMDC_DN | 191 | 41 | 17377 | 2626 |
CHMP2A,GCLM,PKP4,GOLIM4,DHPS,CHIC2,AGPAT3,PMVK,KCMF1,REPS1,PNO1,SRXN1,RAD23A,FKBP1A,SLC31A1,CBWD2,GEMIN6,MDFIC,TAGLN2,LRRC59,MOB4,PPIF,TSHZ1,BAK1,USO1,BIRC3,TMEM39A,USP10,FAM50B,KRTCAP2,PTTG1IP,MBD3,ABCF1,PSMC4,HSPBP1,BRD2,NSF,H2AFX,PRMT7,ZRANB2,MAP3K5 |
| 1.145e-02 | -4.47 | KAECH_DAY8_EFF_VS_MEMORY_CD8_TCELL_DN | MSigDB lists | KAECH_DAY8_EFF_VS_MEMORY_CD8_TCELL_DN | 191 | 41 | 17377 | 2626 |
SLC12A7,IER2,CHERP,DNAJB2,MOGS,RGS2,C19orf48,ABHD14A,GSTK1,USF1,CTSS,RALB,RABGAP1L,IL6ST,BCL2,SLC26A2,FBL,CTDSP2,FTL,ATP13A1,TNFAIP3,RPL6,MAP4K3,ADRB2,LY6E,CYFIP2,VKORC1,KLF6,RHOB,MAT2A,FBXO21,AXIN1,RPLP1,RNF38,DDX5,GALNT10,SMAD1,HEXA,RPS6KC1,EYA2,IPO4 |
| 1.145e-02 | -4.47 | GOLDRATH_NAIVE_VS_EFF_CD8_TCELL_UP | MSigDB lists | GOLDRATH_NAIVE_VS_EFF_CD8_TCELL_UP | 191 | 41 | 17377 | 2626 |
SLC12A7,GALK1,DDX47,PHF23,SF3B1,MCCC1,ACAP1,CCNL2,CDIPT,C19orf48,METTL3,FARSA,IL6ST,SLC44A1,RPAP1,TTC3,TERF2,ABCC5,KAT2A,BAZ2A,PRKDC,MFNG,MAP4K3,ICAM2,VKORC1,KDM3A,POLG2,HAGH,TRIM28,CYB5A,UTP20,HSPB11,ETS2,ARNTL,COX7A2L,DCAF11,RPLP1,CANT1,HEXA,PDCD4,IPO4 |
| 1.145e-02 | -4.47 | GSE5142_CTRL_VS_HTERT_TRANSDUCED_CD8_TCELL_EARLY_PASSAGE_CLONE_UP | MSigDB lists | GSE5142_CTRL_VS_HTERT_TRANSDUCED_CD8_TCELL_EARLY_PASSAGE_CLONE_UP | 191 | 41 | 17377 | 2626 |
CYTIP,TRIM41,GGNBP2,AGRN,VAV2,MXD4,CDIPT,RGS2,NCAPG,LCLAT1,REPS1,RGS1,JMY,CAPN2,RB1,VMP1,IMPAD1,RABGAP1L,MGAT5,TMBIM1,S100A6,MYO5A,MSH6,SMC4,YTHDC1,CYFIP1,TEX10,ARHGEF12,DHX57,CYB5A,MYO1F,DDX17,INF2,ZNF862,AHNAK,MYO18A,ZC3H7B,ITGB1,TATDN1,CD81,BRD9 |
| 1.145e-02 | -4.47 | GSE8685_IL2_STARVED_VS_IL21_ACT_IL2_STARVED_CD4_TCELL_DN | MSigDB lists | GSE8685_IL2_STARVED_VS_IL21_ACT_IL2_STARVED_CD4_TCELL_DN | 191 | 41 | 17377 | 2626 |
ANKRD13D,KRBA1,CHERP,SLC4A2,CHKB,IP6K2,MIS12,ANKLE1,ADD3,RPL17,RABGAP1L,RAB35,LPIN2,DNM2,SOCS5,NIPAL3,CSNK1G2,MAPRE2,DDX24,CSRP1,TSPYL4,DENND1B,RFXANK,COG1,MIER2,WDR81,NDUFA7,RHOT2,SYMPK,MAP2K2,HSPA1B,XRCC5,SEC31A,HGS,TONSL,HPS5,ASNA1,DVL1,BRWD3,NXT2,S100PBP |
| 1.145e-02 | -4.47 | GSE27786_ERYTHROBLAST_VS_MONO_MAC_UP | MSigDB lists | GSE27786_ERYTHROBLAST_VS_MONO_MAC_UP | 191 | 41 | 17377 | 2626 |
GOLPH3L,POC1A,CTCF,KIF2C,PMF1,AP1B1,PRNP,ANKLE1,RB1,ERH,SMC3,SLC1A4,IARS,KNTC1,RNF19A,CLTB,STRAP,ANKRD9,MRPL32,TIMM50,STAU1,PBK,WDR81,BRCA1,CCNF,USP21,RAD51C,LUC7L3,DCK,CDCA5,C1orf109,EXOC4,USP32,PML,H2AFX,C4orf46,FAM126A,DMWD,SASS6,SAT2,GEMIN7 |
| 1.145e-02 | -4.47 | GSE7852_TREG_VS_TCONV_FAT_DN | MSigDB lists | GSE7852_TREG_VS_TCONV_FAT_DN | 191 | 41 | 17377 | 2626 |
MIB2,MRPL9,SMAP1,LETMD1,AGPAT3,JMJD6,AGFG1,SLC12A9,STMN1,SLC20A1,ZADH2,LIN9,DTL,RPA2,MCM5,BDH1,FBXO7,CITED2,PPIF,GCC2,TSPYL4,DENND4C,MAP4K4,CDC6,BMS1,MCM2,C9orf40,PHF6,ASF1B,HSPA1B,EPB41,MYO1F,CHCHD3,KIF2A,SLCO4A1,SGSH,TYW5,CDCA5,ITGB1,C4orf46,GALNT10 |
| 1.145e-02 | -4.47 | negative regulation of cellular amide metabolic process | biological process | GO:0034249 | 190 | 41 | 17256 | 2622 |
UNK,PRKAA1,AGO2,YTHDF3,TIA1,EIF2AK4,METTL3,RBM4,CNOT3,PAIP2,PRNP,MEX3C,EIF4A3,METTL14,DAPK1,CNOT6L,STAT3,SAMD4B,BTG2,ILF3,CIRBP,EIF2AK1,FXR1,DAPK3,CNOT9,EPRS,TSC1,UPF1,EIF4ENIF1,SYNCRIP,ORMDL2,HNRNPR,KHSRP,CTSA,ROCK1,CLU,SNRNP70,CPEB2,TOB1,PURA,RNF139 |
| 1.145e-02 | -4.47 | regulation of histone H3-K4 methylation | biological process | GO:0051569 | 26 | 9 | 17256 | 2622 |
KMT2E,ZNF335,KMT2B,CTR9,H2AFY,RTF1,BRCA1,SMAD4,DNMT1 |
| 1.145e-02 | -4.47 | protein quality control for misfolded or incompletely synthesized proteins | biological process | GO:0006515 | 26 | 9 | 17256 | 2622 |
DERL1,ANKZF1,ATXN3,KLHL15,CUL3,SDF2L1,NGLY1,LONP2,RNF5 |
| 1.145e-02 | -4.47 | microtubule organizing center localization | biological process | GO:0061842 | 26 | 9 | 17256 | 2622 |
KIF5B,EZR,NDC1,BICD2,NDE1,ARPC5,ASPM,INTS13,DYNC1LI2 |
| 1.145e-02 | -4.47 | regulation of telomere capping | biological process | GO:1904353 | 26 | 9 | 17256 | 2622 |
MAP3K4,USP7,ERCC1,NEK7,NABP2,AURKB,MAPK1,TERF2,MAPK3 |
| 1.145e-02 | -4.47 | HA2 | pfam domains | PF04408 | 18 | 7 | 17054 | 2545 |
DHX8,DHX16,DHX29,DHX15,YTHDC2,DHX57,DHX9 |
| 1.146e-02 | -4.47 | Antigen processing-Cross presentation | REACTOME pathways | R-HSA-1236975 | 101 | 26 | 10287 | 1696 |
SEC61B,PSMA8,SEC61G,HLA-E,TAP1,PSMB7,PSMA1,PSMD9,PSMB9,ITGB5,PSMB3,HLA-A,PSMC4,CTSL,HLA-B,PSMD2,PSMA6,CTSS,PSMD1,SEC61A1,RPS27A,PSMD8,SNAP23,PSMD3,TAP2,PSMC1 |
| 1.147e-02 | -4.47 | DNAJA1 (DnaJ heat shock protein family (Hsp40) member A1) | protein interactions | 3301 | 163 | 38 | 17029 | 2761 |
HSPH1,CYLD,TXN,PRKCSH,SUZ12,RAF1,PTTG1,CUL1,CDC73,WWP2,SHC1,PTEN,HUWE1,AHSA1,TRA2B,NUDC,SPTAN1,CDC5L,LDHB,CCT2,USO1,EID1,VHL,CUL3,NFATC2,BRCA1,MCM2,CDC16,HSPA4,OSBPL11,KPNA4,QARS,XRCC3,ACADM,PSAP,FAF1,NUDT3,HDAC2 |
| 1.151e-02 | -4.46 | DORSAM_HOXA9_TARGETS_UP | MSigDB lists | DORSAM_HOXA9_TARGETS_UP | 35 | 11 | 17377 | 2626 |
MAN2A2,SRSF11,ADD3,ST13,ETS2,ARPC5,DHX8,AHCYL1,RPL27A,RNF103,HMGN2 |
| 1.151e-02 | -4.46 | MARZEC_IL2_SIGNALING_DN | MSigDB lists | MARZEC_IL2_SIGNALING_DN | 35 | 11 | 17377 | 2626 |
CDKN2C,DAPK1,RFFL,CDKN1B,IP6K2,TFDP2,PDE3B,FOXO3,STAM,PDCD4,FAS |
| 1.152e-02 | -4.46 | GSE2128_C57BL6_VS_NOD_CD4CD8_DP_THYMOCYTE_DN | MSigDB lists | GSE2128_C57BL6_VS_NOD_CD4CD8_DP_THYMOCYTE_DN | 180 | 39 | 17377 | 2626 |
TMEM106C,TCF12,CASP6,SESTD1,RAF1,ANKH,AKT1S1,EZH1,IKBIP,RCOR3,METTL3,HMG20A,KIAA1147,EDC3,RCSD1,PPCDC,UPF2,RNF19A,CNOT6L,TTLL12,CLN6,N4BP2,SLC25A1,LDHB,ELOVL5,ZNF672,DDX24,STX16,MTR,RAB2B,ANKRD10,SH3BP5,CERS6,ZNF436,GLG1,DCAF11,DTD1,FAU,ACSF2 |
| 1.152e-02 | -4.46 | GSE41867_NAIVE_VS_DAY15_LCMV_EFFECTOR_CD8_TCELL_DN | MSigDB lists | GSE41867_NAIVE_VS_DAY15_LCMV_EFFECTOR_CD8_TCELL_DN | 180 | 39 | 17377 | 2626 |
UBL3,PNISR,RAB11B,SF3B1,TRIM11,CERK,C5orf30,MYH9,KLF13,SMC6,NHLRC3,ASAP2,ADD3,SAR1A,RCSD1,CDKN1B,AFF1,TAF5L,PIKFYVE,SRSF11,CDKN2AIP,CYFIP1,BRD4,FAM49B,AZI2,TOLLIP,TSR2,GIGYF1,DDX23,TFEB,LEMD2,MTMR3,MKNK1,PCM1,UAP1,MYO18A,RBMS1,DVL1,NUMB |
| 1.152e-02 | -4.46 | GSE20727_ROS_INH_VS_ROS_INH_AND_DNFB_ALLERGEN_TREATED_DC_UP | MSigDB lists | GSE20727_ROS_INH_VS_ROS_INH_AND_DNFB_ALLERGEN_TREATED_DC_UP | 180 | 39 | 17377 | 2626 |
KIF3B,RHOC,RRAGC,JMJD6,AGFG1,GYG1,PSMD9,ITGB5,IL21R,CREM,GTF2F1,PTPN2,JAZF1,MEA1,FAM89B,INTS12,CDKN1B,BCAP29,SGCB,CARM1,SNX8,GTF3C6,HMGN5,COQ10B,BTG2,SLC16A7,PFKFB3,KRAS,RHOB,CHMP4A,RBM47,RBMS1,SAMD8,GALNT10,H3F3A,PLOD3,HIPK3,NIPA1,LRCH1 |
| 1.153e-02 | -4.46 | ATGGYGGA_UNKNOWN | MSigDB lists | ATGGYGGA_UNKNOWN | 94 | 23 | 17377 | 2626 |
WASF2,PPP1R21,XIAP,CAMSAP1,KLHL18,YTHDF3,PPP3CB,BRCA1,KDM3A,SLC20A1,CSNK1A1,C19orf48,SYMPK,CRKL,CCNA2,VASP,FASTK,TRA2B,YWHAZ,SLAIN1,MDH1,PURA,CGGBP1 |
| 1.153e-02 | -4.46 | AGGTGCA,MIR-500 | MSigDB lists | AGGTGCA,MIR-500 | 94 | 23 | 17377 | 2626 |
UBE2D3,RAB14,IVNS1ABP,SHPRH,E2F3,C5orf30,MYNN,MATR3,POFUT1,LRRC14,NRF1,CACNB1,RAB21,CCDC6,SEC24C,PPP4R1,OGT,RNF38,PDS5B,RBMS1,ZRANB2,NCOA1,CREB1 |
| 1.154e-02 | -4.46 | GSE21033_1H_VS_12H_POLYIC_STIM_DC_UP | MSigDB lists | GSE21033_1H_VS_12H_POLYIC_STIM_DC_UP | 169 | 37 | 17377 | 2626 |
USP7,PTMS,TMEM184B,AGTRAP,ARID2,URB2,PHRF1,UCK2,PTP4A3,PPP1R16B,PPP1R3B,C1GALT1,NFATC3,HDAC7,ANXA5,AHDC1,RPRD1B,RNF169,TTPAL,PDPK1,PPT1,BTG2,USP42,PFKFB3,EZR,NFATC2,DCLRE1C,CYFIP2,TOLLIP,PLEKHF2,DOT1L,PTPRF,CACNB1,VPS26B,DCK,TCOF1,GLCCI1 |
| 1.154e-02 | -4.46 | GSE11864_CSF1_VS_CSF1_PAM3CYS_IN_MAC_DN | MSigDB lists | GSE11864_CSF1_VS_CSF1_PAM3CYS_IN_MAC_DN | 169 | 37 | 17377 | 2626 |
HIVEP3,TMUB1,TRAF7,SECISBP2,ETS1,LYN,PIP5K1C,RAD23A,SF3B2,ABL2,RAB21,ASAP2,BRPF3,RAD23B,ZNF335,NOC2L,GEMIN4,FBXL19,PPA1,PRPF19,PPIF,SEC61B,EXOSC6,BIRC3,MTA2,USP42,EIF2A,DCUN1D5,GAR1,ORMDL2,TFDP1,DTX4,NUP62,SMURF1,PSMC1,MRPL3,IPO4 |
| 1.157e-02 | -4.46 | GO_DNA_HELICASE_ACTIVITY | MSigDB lists | GO_DNA_HELICASE_ACTIVITY | 49 | 14 | 17377 | 2626 |
GINS1,RECQL,CHD3,MCM5,HELB,CHD1L,DHX9,RUVBL2,BLM,MCM2,CHD1,GINS4,RAD54B,XRCC5 |
| 1.157e-02 | -4.46 | WONG_PROTEASOME_GENE_MODULE | MSigDB lists | WONG_PROTEASOME_GENE_MODULE | 49 | 14 | 17377 | 2626 |
FBXO21,PSMD1,UBE2Q2,SIAH1,PSMD8,PSMD3,SIAH2,PSMA1,USP39,USP10,USP11,UBE2C,PSMB3,USP13 |
| 1.157e-02 | -4.46 | PID_PI3KCI_PATHWAY | MSigDB lists | PID_PI3KCI_PATHWAY | 49 | 14 | 17377 | 2626 |
PDPK1,CYTH1,RAP1A,RHOA,NRAS,PTEN,ARF5,PIK3R2,RAC1,KRAS,ARF1,LYN,FOXO3,HRAS |
| 1.157e-02 | -4.46 | PELLICCIOTTA_HDAC_IN_ANTIGEN_PRESENTATION_DN | MSigDB lists | PELLICCIOTTA_HDAC_IN_ANTIGEN_PRESENTATION_DN | 49 | 14 | 17377 | 2626 |
DERL1,HLA-B,PSMA6,PSMD8,TAP1,PSMA1,TAP2,PDIA6,PSMB9,NGLY1,PSMC1,SERP1,HLA-A,KDELR1 |
| 1.157e-02 | -4.46 | lumenal side of membrane | cellular component | GO:0098576 | 4 | 3 | 18223 | 2701 |
NUCB1,CTSA,BDH1 |
| 1.157e-02 | -4.46 | calcineurin complex | cellular component | GO:0005955 | 4 | 3 | 18223 | 2701 |
PPP3CA,PPP3CB,PPP3R1 |
| 1.157e-02 | -4.46 | gamma-tubulin small complex | cellular component | GO:0008275 | 4 | 3 | 18223 | 2701 |
MZT1,CENPJ,TUBGCP2 |
| 1.157e-02 | -4.46 | MIS12/MIND type complex | cellular component | GO:0000444 | 4 | 3 | 18223 | 2701 |
PMF1,DSN1,MIS12 |
| 1.157e-02 | -4.46 | Sec61 translocon complex | cellular component | GO:0005784 | 4 | 3 | 18223 | 2701 |
SEC61B,BCAP31,ARL6IP1 |
| 1.157e-02 | -4.46 | translocon complex | cellular component | GO:0071256 | 4 | 3 | 18223 | 2701 |
SEC61B,BCAP31,ARL6IP1 |
| 1.157e-02 | -4.46 | Mon1-Ccz1 complex | cellular component | GO:0035658 | 4 | 3 | 18223 | 2701 |
CCZ1,RMC1,MON1B |
| 1.157e-02 | -4.46 | BENPORATH_OCT4_TARGETS | MSigDB lists | BENPORATH_OCT4_TARGETS | 270 | 55 | 17377 | 2626 |
UBE2D3,TCF12,USP7,PNISR,GADD45G,ORC1,SUPT7L,MYEF2,ARID1B,HMG20A,APOPT1,NPLOC4,PIP5K1C,PTPN2,GTPBP3,ADD3,KLHL5,ARPC5,DPYSL2,SRSF4,SLC44A1,JOSD1,DDX31,TALDO1,STAT3,ATP6V1G1,CDC123,RDH10,KIF15,FRAT2,DNAJC9,EXOSC9,CAPZA2,ICMT,KDM3A,LSG1,RAD54B,DPYSL3,MAGED2,RAD51C,HHEX,INF2,ATP6V1D,PLAA,ATAD2,RPL32,PARG,HMGB2,TAF12,NR2F2,MRPL13,TSTD2,CABLES1,PARD3,IFI16 |
| 1.157e-02 | -4.46 | response to decreased oxygen levels | biological process | GO:0036293 | 343 | 68 | 17256 | 2622 |
DNMT3A,NF1,RAF1,ALKBH5,SLC29A1,SIRT2,CCNB1,BECN1,BIRC2,EEF2K,USF1,CCNA2,PSMA6,MDM2,PSMD1,CDKN1B,PLK3,RBX1,PSMA8,VHL,PSMB7,PSMB9,SCAP,RPS27A,PSMD8,PSMD3,HIPK2,PSMC1,SMAD4,UBE2D3,TM9SF4,AGTRAP,PHB2,MECP2,PRKAA1,PSMD9,ETS1,FOXO3,LMNA,CFLAR,CAPN2,PSMD2,TIGAR,SUV39H2,PTEN,AHCY,BCL2,CREB1,CITED2,HP1BP3,TGFB1,ADAM17,RHOA,ERO1A,LDHA,ADSL,PSMA1,PKM,PSMB3,PSMC4,CAT,TSC1,PDLIM1,PML,E2F1,RBPJ,CPEB2,EGLN1 |
| 1.157e-02 | -4.46 | Longevity regulating pathway | KEGG pathways | hsa04211 | 89 | 23 | 7161 | 1149 |
PRKAB1,NRAS,TSC2,RB1CC1,AKT2,PRKAA1,EHMT1,KRAS,AKT1S1,PRKACA,FOXO3,APPL1,RHEB,CAT,TSC1,ADCY9,PIK3R2,STK11,ATG13,CREB1,ATF2,HRAS,ADCY7 |
| 1.158e-02 | -4.46 | shelterin complex | cellular component | GO:0070187 | 7 | 4 | 18223 | 2701 |
TERF2IP,POT1,TERF1,TERF2 |
| 1.158e-02 | -4.46 | Rad51B-Rad51C-Rad51D-XRCC2 complex | cellular component | GO:0033063 | 7 | 4 | 18223 | 2701 |
XRCC3,RAD51C,RAD51D,XRCC2 |
| 1.158e-02 | -4.46 | spindle pole body | cellular component | GO:0005816 | 7 | 4 | 18223 | 2701 |
NDC1,MZT1,TUBGCP2,TUBGCP5 |
| 1.158e-02 | -4.46 | Mre11 complex | cellular component | GO:0030870 | 7 | 4 | 18223 | 2701 |
TERF2IP,MRNIP,SP100,TERF2 |
| 1.159e-02 | -4.46 | peptidyl-prolyl cis-trans isomerase activity | molecular function | GO:0003755 | 39 | 12 | 17224 | 2647 |
FKBP1A,PPIF,PPIB,CWC27,PPIG,PIN1,PPIE,PPIL2,FKBP5,PPWD1,FKBP2,FKBP3 |
| 1.159e-02 | -4.46 | Hsp90 protein binding | molecular function | GO:0051879 | 39 | 12 | 17224 | 2647 |
CDK5,TELO2,TSC1,TSC2,AHSA1,ARNTL,CSNK2A1,NUP62,PTGES3,TTC4,PPP5C,CDC37 |
| 1.164e-02 | -4.45 | ribosome binding | molecular function | GO:0043022 | 53 | 15 | 17224 | 2647 |
SRP72,EIF5A,GEMIN5,EIF3K,SEC61A1,PELO,MRPS27,YTHDF3,LETMD1,RPN2,EIF2A,EFL1,CPEB2,ZNF598,RPSA |
| 1.164e-02 | -4.45 | TSC22D1 (TSC22 domain family member 1) | protein interactions | 8848 | 88 | 23 | 17029 | 2761 |
UNK,SNRNP200,WDYHV1,TSC22D3,DNAAF5,ASAH1,SLC25A22,KMT2C,GNB2,MTR,COPB2,RGS1,GSTK1,IARS,CHD3,QARS,KMT2B,TAF5L,CDK2,NRBP1,ZC3HC1,FAF1,HNRNPM |
| 1.164e-02 | -4.45 | FKBP4 (FK506 binding protein 4) | protein interactions | 2288 | 88 | 23 | 17029 | 2761 |
PRKAB1,NPHP4,EWSR1,POC1A,CSNK2A1,BRCA1,MCM2,FOXO3,CDC73,PTPN2,FKBP1A,IRF4,HSPA4,AHSA1,UBA5,DDA1,SH3GLB2,PTGES3,CDK2,NIPSNAP2,S100A6,CDC37,EGLN1 |
| 1.165e-02 | -4.45 | Helicase-assoc_dom | interpro domains | IPR007502 | 18 | 7 | 18492 | 2768 |
DHX8,DHX16,DHX29,DHX57,DHX15,YTHDC2,DHX9 |
| 1.165e-02 | -4.45 | autonomic_ganglia-para_aortic-paraganglioma-benign | COSMIC cancer mutations | autonomic_ganglia-para_aortic-paraganglioma-benign | 31 | 10 | 17385 | 2587 |
GUK1,GALC,RAB35,NOTCH2,WIPI2,KMT2C,STYXL1,PRPSAP1,SDHA,CHD1 |
| 1.165e-02 | -4.45 | sternum | COSMIC cancer mutations | sternum | 31 | 10 | 17385 | 2587 |
GNAS,RB1,AHNAK,EWSR1,ARL6IP1,H3F3A,CDKN2A,NUP205,KRR1,LDHB |
| 1.165e-02 | -4.45 | para_aortic | COSMIC cancer mutations | para_aortic | 31 | 10 | 17385 | 2587 |
GUK1,GALC,RAB35,NOTCH2,WIPI2,KMT2C,STYXL1,PRPSAP1,SDHA,CHD1 |
| 1.165e-02 | -4.45 | negative regulation of protein kinase activity | biological process | GO:0006469 | 263 | 54 | 17256 | 2622 |
FGFR1OP,GGNBP2,TSC2,GMFG,NF1,CIB1,AKT1S1,RGS2,LYN,DUSP22,PSEN1,VPS25,PARK7,PTPN2,TFAP4,CDKN2C,RB1,PTEN,FBXO7,SOCS6,DUS2,H2AFY,CDKN1B,MVP,SOCS5,CHP1,PLK1,PDPK1,TNFAIP3,NCK1,GBA,GMFB,PRKAR1B,LRP5,DNAJA1,MEN1,SOCS7,PPP2CA,SH3BP5,HHEX,MBIP,GPS2,DUSP3,QARS,STK38,CORO1C,GADD45B,SOCS4,NUP62,DVL1,NR2F2,HIPK3,CDKN2A,PDCD4 |
| 1.169e-02 | -4.45 | Rossmann-like_a/b/a_fold | interpro domains | IPR014729 | 40 | 12 | 18492 | 2768 |
FLAD1,CTU2,LARS,EPRS,NADSYN1,IARS,QARS,TRMU,IARS2,CRY2,PCYT2,CARS2 |
| 1.170e-02 | -4.45 | small_cell_adenocarcinoma | COSMIC cancer mutations | small_cell_adenocarcinoma | 4 | 3 | 17385 | 2587 |
KRAS,SF3B1,CDKN2A |
| 1.170e-02 | -4.45 | haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-plasmacytoma | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-plasmacytoma | 4 | 3 | 17385 | 2587 |
KRAS,NRAS,VHL |
| 1.170e-02 | -4.45 | juvenile_polyp | COSMIC cancer mutations | juvenile_polyp | 4 | 3 | 17385 | 2587 |
KRAS,PTEN,SMAD4 |
| 1.170e-02 | -4.45 | T_cell_leukaemia_not_otherwise_specified | COSMIC cancer mutations | T_cell_leukaemia_not_otherwise_specified | 4 | 3 | 17385 | 2587 |
CDKN2C,STAT3,CDKN2A |
| 1.170e-02 | -4.45 | central_nervous_system-other-neoplasm | COSMIC cancer mutations | central_nervous_system-other-neoplasm | 4 | 3 | 17385 | 2587 |
NRAS,PTEN,CDKN2A |
| 1.170e-02 | -4.45 | fibroxanthoma | COSMIC cancer mutations | fibroxanthoma | 4 | 3 | 17385 | 2587 |
KRAS,NRAS,HRAS |
| 1.170e-02 | -4.45 | skin-abdomen-benign_melanocytic_nevus-junctional | COSMIC cancer mutations | skin-abdomen-benign_melanocytic_nevus-junctional | 4 | 3 | 17385 | 2587 |
KRAS,NRAS,HRAS |
| 1.170e-02 | -4.45 | skin-lower_leg-malignant_melanoma-nodular | COSMIC cancer mutations | skin-lower_leg-malignant_melanoma-nodular | 4 | 3 | 17385 | 2587 |
KRAS,NRAS,HRAS |
| 1.170e-02 | -4.45 | skin-malignant_melanoma-amelanotic | COSMIC cancer mutations | skin-malignant_melanoma-amelanotic | 4 | 3 | 17385 | 2587 |
NRAS,PTEN,CDKN2A |
| 1.170e-02 | -4.45 | metacarpus | COSMIC cancer mutations | metacarpus | 4 | 3 | 17385 | 2587 |
RB1,EWSR1,CDKN2A |
| 1.170e-02 | -4.45 | pituitary-carcinoma | COSMIC cancer mutations | pituitary-carcinoma | 4 | 3 | 17385 | 2587 |
KRAS,NRAS,HRAS |
| 1.170e-02 | -4.45 | endometrium-other-endometrial_polyp | COSMIC cancer mutations | endometrium-other-endometrial_polyp | 4 | 3 | 17385 | 2587 |
KRAS,NRAS,HRAS |
| 1.170e-02 | -4.45 | large_cell_undifferentiated_carcinoma | COSMIC cancer mutations | large_cell_undifferentiated_carcinoma | 4 | 3 | 17385 | 2587 |
KRAS,NRAS,HRAS |
| 1.170e-02 | -4.45 | adrenal_gland-extraadrenal-pheochromocytoma | COSMIC cancer mutations | adrenal_gland-extraadrenal-pheochromocytoma | 4 | 3 | 17385 | 2587 |
GNAS,CDKN2C,PTEN |
| 1.170e-02 | -4.45 | stomach-carcinoma-small_cell_adenocarcinoma | COSMIC cancer mutations | stomach-carcinoma-small_cell_adenocarcinoma | 4 | 3 | 17385 | 2587 |
KRAS,SF3B1,CDKN2A |
| 1.170e-02 | -4.45 | pancreas-carcinoma-large_cell_neuroendocrine_carcinoma | COSMIC cancer mutations | pancreas-carcinoma-large_cell_neuroendocrine_carcinoma | 4 | 3 | 17385 | 2587 |
RB1,KRAS,CDKN2A |
| 1.170e-02 | -4.45 | haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-T_cell_leukaemia_not_otherwise_specified | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-T_cell_leukaemia_not_otherwise_specified | 4 | 3 | 17385 | 2587 |
CDKN2C,STAT3,CDKN2A |
| 1.170e-02 | -4.45 | skin-forearm-carcinoma-basal_cell_carcinoma | COSMIC cancer mutations | skin-forearm-carcinoma-basal_cell_carcinoma | 4 | 3 | 17385 | 2587 |
KRAS,NRAS,HRAS |
| 1.170e-02 | -4.45 | pancreas-carcinoma-small_cell_carcinoma | COSMIC cancer mutations | pancreas-carcinoma-small_cell_carcinoma | 4 | 3 | 17385 | 2587 |
RB1,KRAS,CDKN2A |
| 1.170e-02 | -4.45 | autonomic_ganglia-thoraco-abdomen-paraganglioma | COSMIC cancer mutations | autonomic_ganglia-thoraco-abdomen-paraganglioma | 4 | 3 | 17385 | 2587 |
KRAS,NRAS,HRAS |
| 1.170e-02 | -4.45 | pituitary-carcinoma-ACTH | COSMIC cancer mutations | pituitary-carcinoma-ACTH | 4 | 3 | 17385 | 2587 |
KRAS,NRAS,HRAS |
| 1.170e-02 | -4.45 | amelanotic | COSMIC cancer mutations | amelanotic | 4 | 3 | 17385 | 2587 |
NRAS,PTEN,CDKN2A |
| 1.170e-02 | -4.45 | salivary_gland-parotid-carcinoma-large_cell_undifferentiated_carcinoma | COSMIC cancer mutations | salivary_gland-parotid-carcinoma-large_cell_undifferentiated_carcinoma | 4 | 3 | 17385 | 2587 |
KRAS,NRAS,HRAS |
| 1.170e-02 | -4.45 | salivary_gland-parotid-carcinoma-adenocarcinoma | COSMIC cancer mutations | salivary_gland-parotid-carcinoma-adenocarcinoma | 4 | 3 | 17385 | 2587 |
KRAS,NRAS,HRAS |
| 1.170e-02 | -4.45 | skin-buttock-malignant_melanoma-superficial_spreading | COSMIC cancer mutations | skin-buttock-malignant_melanoma-superficial_spreading | 4 | 3 | 17385 | 2587 |
KRAS,NRAS,HRAS |
| 1.170e-02 | -4.45 | large_intestine-colon-other-ulcerative_colitis | COSMIC cancer mutations | large_intestine-colon-other-ulcerative_colitis | 4 | 3 | 17385 | 2587 |
KRAS,NRAS,HRAS |
| 1.170e-02 | -4.45 | skin-upper_arm-carcinoma-basal_cell_carcinoma | COSMIC cancer mutations | skin-upper_arm-carcinoma-basal_cell_carcinoma | 4 | 3 | 17385 | 2587 |
KRAS,NRAS,HRAS |
| 1.170e-02 | -4.45 | endometrial_polyp | COSMIC cancer mutations | endometrial_polyp | 4 | 3 | 17385 | 2587 |
KRAS,NRAS,HRAS |
| 1.170e-02 | -4.45 | thoraco-abdomen | COSMIC cancer mutations | thoraco-abdomen | 4 | 3 | 17385 | 2587 |
KRAS,NRAS,HRAS |
| 1.170e-02 | -4.45 | DOCK5 (dedicator of cytokinesis 5) | protein interactions | 80005 | 55 | 16 | 17029 | 2761 |
CRKL,NOL11,KIAA0100,ELMO1,WDR59,CDCA5,KIAA0232,ATXN1,TGOLN2,ATG2B,RNASEL,TRIM65,MTR,SPSB3,VPS13B,CDC5L |
| 1.170e-02 | -4.45 | SEC23B (Sec23 homolog B, coat complex II component) | protein interactions | 10483 | 55 | 16 | 17029 | 2761 |
SUMO2,CUL3,TMEM216,BRCA1,MCM2,CSNK1A1,SEC16A,CAND1,SEC31A,TMED10,SEC24C,CENPJ,SRSF3,TMED2,SRPK2,KDELR1 |
| 1.170e-02 | -4.45 | CCDC59 (coiled-coil domain containing 59) | protein interactions | 29080 | 55 | 16 | 17029 | 2761 |
MOB4,DAP3,SYNCRIP,URB2,NOA1,VHL,RPS14,RBM34,MAGED1,POP7,DCP1A,HAUS4,SNRNP70,APP,EDC3,DDX52 |
| 1.170e-02 | -4.45 | TRIM8 (tripartite motif containing 8) | protein interactions | 81603 | 55 | 16 | 17029 | 2761 |
UBE2D3,USP7,TRIM8,TNFAIP3,XIAP,BRAP,USP39,UBE2V1,BLM,USP21,TRIM47,RAD18,SIAH1,PTEN,UHRF2,TRAF5 |
| 1.173e-02 | -4.45 | chr19p13 | MSigDB lists | chr19p13 | 480 | 91 | 17377 | 2626 |
IER2,CHERP,RAB11B,DCAF15,TRIP10,PRKCSH,XAB2,COPE,SMARCA4,SAFB2,PRKACA,ZNF121,CD320,RAD23A,VAV1,ANKLE1,FARSA,RAB8A,PIN1,AKAP8,AP1M1,MRPL34,TNPO2,SCAMP4,RNASEH2A,MARCH2,TECR,DNMT1,CARM1,ELOF1,GPX4,CDC37,ZNF559,ATP13A1,BRD4,GNG7,CIRBP,MIER2,NDUFA7,IL12RB1,MBD3,EIF3G,ASF1B,CHAF1A,DOT1L,SUGP1,ZNF317,TIMM13,DUS3L,ZNF700,SAFB,GADD45B,NDUFA11,STK11,NCLN,TICAM1,OAZ1,ZNF564,C19orf53,SH2D3A,DHPS,MUM1,MRI1,TCF3,MYO9B,DNAJB1,NDUFS7,PIP5K1C,GTF2F1,KRI1,GTPBP3,KLF16,MRPL54,HNRNPM,PPAN,CSNK1G2,SUGP2,WDR18,ILF3,DDX39A,SPPL2B,SF3A2,MAP2K2,DAPK3,MYO1F,HAUS8,RPL36,KEAP1,UPF1,KHSRP,ASNA1 |
| 1.174e-02 | -4.44 | salivary_gland-pterygopalatine_fossa-carcinoma-adenoid_cystic_carcinoma | COSMIC cancer mutations | salivary_gland-pterygopalatine_fossa-carcinoma-adenoid_cystic_carcinoma | 7 | 4 | 17385 | 2587 |
KRAS,NRAS,PTEN,HRAS |
| 1.174e-02 | -4.44 | pterygopalatine_fossa | COSMIC cancer mutations | pterygopalatine_fossa | 7 | 4 | 17385 | 2587 |
KRAS,NRAS,PTEN,HRAS |
| 1.174e-02 | -4.44 | salivary_gland-paranasal_sinus-carcinoma-adenoid_cystic_carcinoma | COSMIC cancer mutations | salivary_gland-paranasal_sinus-carcinoma-adenoid_cystic_carcinoma | 7 | 4 | 17385 | 2587 |
KRAS,NRAS,PTEN,HRAS |
| 1.174e-02 | -4.44 | skin-benign_melanocytic_nevus-compound | COSMIC cancer mutations | skin-benign_melanocytic_nevus-compound | 7 | 4 | 17385 | 2587 |
FGFR3,KRAS,NRAS,HRAS |
| 1.174e-02 | -4.44 | skin-neck-other-seborrhoeic_keratosis | COSMIC cancer mutations | skin-neck-other-seborrhoeic_keratosis | 7 | 4 | 17385 | 2587 |
FGFR3,PTEN,HRAS,PTPN11 |
| 1.174e-02 | -4.44 | haematopoietic_and_lymphoid_tissue-lymph_node-lymphoid_neoplasm-anaplastic_large_cell_lymphoma | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-lymph_node-lymphoid_neoplasm-anaplastic_large_cell_lymphoma | 7 | 4 | 17385 | 2587 |
RHOA,TFG,STAT3,ATIC |
| 1.174e-02 | -4.44 | nevus_sebaceous | COSMIC cancer mutations | nevus_sebaceous | 7 | 4 | 17385 | 2587 |
FGFR3,KRAS,NRAS,HRAS |
| 1.174e-02 | -4.44 | endometrium-carcinoma-squamous_cell_carcinoma | COSMIC cancer mutations | endometrium-carcinoma-squamous_cell_carcinoma | 7 | 4 | 17385 | 2587 |
KRAS,NRAS,PTEN,HRAS |
| 1.174e-02 | -4.44 | oesophagus-other-Barrett_oesophagus | COSMIC cancer mutations | oesophagus-other-Barrett_oesophagus | 7 | 4 | 17385 | 2587 |
KRAS,NRAS,HRAS,CDKN2A |
| 1.174e-02 | -4.44 | haematopoietic_and_lymphoid_tissue-thyroid-lymphoid_neoplasm-MALT_lymphoma | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-thyroid-lymphoid_neoplasm-MALT_lymphoma | 7 | 4 | 17385 | 2587 |
KRAS,NRAS,TNFAIP3,HRAS |
| 1.174e-02 | -4.44 | skin-face-malignant_melanoma-nodular | COSMIC cancer mutations | skin-face-malignant_melanoma-nodular | 7 | 4 | 17385 | 2587 |
KRAS,NRAS,HRAS,CDKN2A |
| 1.174e-02 | -4.44 | dysplastic | COSMIC cancer mutations | dysplastic | 7 | 4 | 17385 | 2587 |
KRAS,NRAS,HRAS,CDKN2A |
| 1.174e-02 | -4.44 | skin-face-adnexal_tumour-malignant_adnexal_tumour | COSMIC cancer mutations | skin-face-adnexal_tumour-malignant_adnexal_tumour | 7 | 4 | 17385 | 2587 |
FGFR3,KRAS,NRAS,HRAS |
| 1.174e-02 | -4.44 | Barrett_oesophagus | COSMIC cancer mutations | Barrett_oesophagus | 7 | 4 | 17385 | 2587 |
KRAS,NRAS,HRAS,CDKN2A |
| 1.174e-02 | -4.44 | endometrium-hyperplasia-atypical | COSMIC cancer mutations | endometrium-hyperplasia-atypical | 7 | 4 | 17385 | 2587 |
KRAS,NRAS,PTEN,HRAS |
| 1.174e-02 | -4.44 | ulcerative_colitis | COSMIC cancer mutations | ulcerative_colitis | 7 | 4 | 17385 | 2587 |
KRAS,NRAS,HRAS,SMAD4 |
| 1.174e-02 | -4.44 | skin-shoulder-other-seborrhoeic_keratosis | COSMIC cancer mutations | skin-shoulder-other-seborrhoeic_keratosis | 7 | 4 | 17385 | 2587 |
FGFR3,PTEN,HRAS,PTPN11 |
| 1.174e-02 | -4.44 | skin-other-nevus_sebaceous | COSMIC cancer mutations | skin-other-nevus_sebaceous | 7 | 4 | 17385 | 2587 |
FGFR3,KRAS,NRAS,HRAS |
| 1.174e-02 | -4.44 | skin-forearm-carcinoma-squamous_cell_carcinoma | COSMIC cancer mutations | skin-forearm-carcinoma-squamous_cell_carcinoma | 7 | 4 | 17385 | 2587 |
KRAS,NOTCH2,NRAS,HRAS |
| 1.174e-02 | -4.44 | skin-chest-other-seborrhoeic_keratosis | COSMIC cancer mutations | skin-chest-other-seborrhoeic_keratosis | 7 | 4 | 17385 | 2587 |
FGFR3,PTEN,HRAS,PTPN11 |
| 1.179e-02 | -4.44 | GO_ANTIGEN_PROCESSING_AND_PRESENTATION_OF_PEPTIDE_ANTIGEN_VIA_MHC_CLASS_I | MSigDB lists | GO_ANTIGEN_PROCESSING_AND_PRESENTATION_OF_PEPTIDE_ANTIGEN_VIA_MHC_CLASS_I | 89 | 22 | 17377 | 2626 |
PSMA8,HLA-E,TAP1,PSMB7,PSMA1,ITGB5,PSMB9,PSMD9,BCAP31,PSMB3,HLA-A,PSMC4,SEC31A,HLA-B,PSMD2,PSMA6,PSMD1,PSMD8,SEC24C,PSMD3,TAP2,PSMC1 |
| 1.179e-02 | -4.44 | LEE_CALORIE_RESTRICTION_NEOCORTEX_DN | MSigDB lists | LEE_CALORIE_RESTRICTION_NEOCORTEX_DN | 89 | 22 | 17377 | 2626 |
HIVEP3,C19orf53,POLR2G,RAC1,VDAC2,RBM4,TARS,TFRC,CHKA,KIF5B,CALM2,EPRS,CLIC4,IARS,ATP2A2,STAT6,NAGLU,ACLY,PML,H2AFX,PHKG2,EEF1D |
| 1.179e-02 | -4.44 | anaplastic_large_cell_lymphoma | COSMIC cancer mutations | anaplastic_large_cell_lymphoma | 45 | 13 | 17385 | 2587 |
FGFR3,RB1,RHOA,NRAS,PTEN,VHL,ATIC,STK11,KRAS,TFG,STAT3,HRAS,CDKN2A |
| 1.180e-02 | -4.44 | AP3D1 (adaptor related protein complex 3 subunit delta 1) | protein interactions | 8943 | 46 | 14 | 17029 | 2761 |
STAU1,DAP3,RBM25,AP3S2,CENPJ,AP3M2,ARF1,CDK11B,CLTB,ARRB2,AP3S1,RUFY1,F2R,CDC73 |
| 1.180e-02 | -4.44 | SPECC1L (sperm antigen with calponin homology and coiled-coil domains 1 like) | protein interactions | 23384 | 46 | 14 | 17029 | 2761 |
VAV1,GLIS2,TWNK,MYO18A,KCTD17,MYH9,RPL15,CAPZA2,UBE2I,ANLN,CDK2,DUSP22,ECPAS,ATMIN |
| 1.180e-02 | -4.44 | TSPYL6 (TSPY like 6) | protein interactions | 388951 | 46 | 14 | 17029 | 2761 |
MDM2,NSMCE4A,TRAF7,DDX24,WDR59,RRBP1,KIAA0232,KBTBD7,SMC6,GUF1,MAD2L2,WDR48,USP34,ZMYM3 |
| 1.180e-02 | -4.44 | BUD31 (BUD31 homolog) | protein interactions | 8896 | 46 | 14 | 17029 | 2761 |
CTNNBL1,RRBP1,PPIE,ZNF326,SRSF3,ISY1-RAB43,SEPT7,DCUN1D4,NKAPD1,SGF29,APP,SF3A2,PRPF19,ADCY7 |
| 1.180e-02 | -4.44 | STAU2 (staufen double-stranded RNA binding protein 2) | protein interactions | 27067 | 46 | 14 | 17029 | 2761 |
PPAN,NIFK,STAU1,RPS2,UPF1,STRBP,DGCR8,RPL6,RPL8,PRKRA,MATR3,PAIP1,ZC3HAV1,GPATCH4 |
| 1.180e-02 | -4.44 | ADSS (adenylosuccinate synthase) | protein interactions | 159 | 46 | 14 | 17029 | 2761 |
PTMS,GART,CHMP4A,GNPNAT1,ANXA6,DCK,WDR1,CUL3,ARMT1,OAT,TALDO1,MAPK14,IMPA2,CBX3 |
| 1.180e-02 | -4.44 | BABAM2 (BRISC and BRCA1 A complex member 2) | protein interactions | 9577 | 46 | 14 | 17029 | 2761 |
HNRNPA2B1,USP7,ABRAXAS2,SUMO2,BABAM1,LRPPRC,TMX3,RPN2,BRCA1,TFG,DEF6,OPTN,WWP2,FAS |
| 1.180e-02 | -4.44 | PALLD (palladin, cytoskeletal associated protein) | protein interactions | 23022 | 46 | 14 | 17029 | 2761 |
SKA3,NDUFV1,CENPJ,ACOX1,ODF2,MYH9,EZR,BRCA1,CNTROB,MCM2,ITGB5,IGBP1,ISG15,SRPK2 |
| 1.180e-02 | -4.44 | ASPSCR1 (ASPSCR1, UBX domain containing tether for SLC2A4) | protein interactions | 79058 | 46 | 14 | 17029 | 2761 |
UBXN2A,NSF,UBXN2B,BANF1,DCAF11,NSFL1C,VCPIP1,GLTP,ASNA1,FAM136A,APP,TACC3,NPLOC4,FAF1 |
| 1.180e-02 | -4.44 | UBE3C (ubiquitin protein ligase E3C) | protein interactions | 9690 | 46 | 14 | 17029 | 2761 |
UBE2D3,PSMD2,GOLGA2,MTA1,MTA2,TLK1,FAM3C,UBE3C,CCNB1,RBM15,PCBP1,APP,USP13,EEF2K |
| 1.180e-02 | -4.44 | MLST8 (MTOR associated protein, LST8 homolog) | protein interactions | 64223 | 46 | 14 | 17029 | 2761 |
MTMR3,CCT2,PFDN5,KEAP1,ETV3,THADA,ZNRF2,SUZ12,STAT1,APPL2,ATXN1,KIF11,LYPLA2,RHEB |
| 1.180e-02 | -4.44 | KCTD10 (potassium channel tetramerization domain containing 10) | protein interactions | 83892 | 46 | 14 | 17029 | 2761 |
PCNA,ATXN3,TNFAIP3,PPP1R21,UBXN1,EXOSC1,MYO18A,RAD23B,CUL3,XRCC3,CAPZA2,COPS6,FAF1,USP13 |
| 1.180e-02 | -4.44 | SS18 (SS18, nBAF chromatin remodeling complex subunit) | protein interactions | 6760 | 46 | 14 | 17029 | 2761 |
PHF10,SYNCRIP,ARID2,SUZ12,CUL3,BCL7C,SMARCA4,ARID1A,ATF2,BRD9,SMARCE1,ARID1B,HDAC2,SMARCD1 |
| 1.180e-02 | -4.44 | Dus | pfam domains | PF01207 | 4 | 3 | 17054 | 2545 |
DUS3L,DUS4L,DUS2 |
| 1.180e-02 | -4.44 | MHC_I_C | pfam domains | PF06623 | 4 | 3 | 17054 | 2545 |
HLA-B,HLA-E,HLA-A |
| 1.180e-02 | -4.44 | UAA | pfam domains | PF08449 | 4 | 3 | 17054 | 2545 |
SLC35B2,SLC35B1,SLC35B4 |
| 1.180e-02 | -4.44 | LUC7 | pfam domains | PF03194 | 4 | 3 | 17054 | 2545 |
LUC7L,LUC7L3,LUC7L2 |
| 1.180e-02 | -4.44 | SNARE_assoc | pfam domains | PF09335 | 4 | 3 | 17054 | 2545 |
TMEM41A,VMP1,TMEM41B |
| 1.180e-02 | -4.44 | MTS | pfam domains | PF05175 | 4 | 3 | 17054 | 2545 |
HEMK1,PRMT2,METTL5 |
| 1.180e-02 | -4.44 | Ligase_CoA | pfam domains | PF00549 | 4 | 3 | 17054 | 2545 |
SUCLG2,SUCLG1,ACLY |
| 1.180e-02 | -4.44 | HJURP_C | pfam domains | PF12347 | 4 | 3 | 17054 | 2545 |
MEF2A,MEF2D,HJURP |
| 1.180e-02 | -4.44 | DUF1394 | pfam domains | PF07159 | 4 | 3 | 17054 | 2545 |
CYFIP1,FAM49B,CYFIP2 |
| 1.180e-02 | -4.44 | GST_C_6 | pfam domains | PF17171 | 4 | 3 | 17054 | 2545 |
MTX1,MTX3,MTX2 |
| 1.180e-02 | -4.44 | SEP | pfam domains | PF08059 | 4 | 3 | 17054 | 2545 |
UBXN2A,UBXN2B,NSFL1C |
| 1.180e-02 | -4.44 | intrinsic component of Golgi membrane | cellular component | GO:0031228 | 50 | 14 | 18223 | 2701 |
YIF1A,GALNT2,SYS1,GOLGA7,SLC35B4,SLC39A13,MFNG,TPST1,PCSK7,YIF1B,SAMD8,SLC35B1,SLC35B2,QSOX2 |
| 1.180e-02 | -4.44 | PcG protein complex | cellular component | GO:0031519 | 50 | 14 | 18223 | 2701 |
PHC2,EPOP,SUZ12,PCGF6,CSNK2A1,H2AFY,EZH1,PCGF1,RBBP4,YY1,ASXL2,CBX4,HDAC2,RYBP |
| 1.184e-02 | -4.44 | CCNT1 (cyclin T1) | protein interactions | 904 | 69 | 19 | 17029 | 2761 |
MAX,BRD4,ELL2,MYBL2,NSD3,KDM1B,RPS9,PIP4K2A,POLR2A,GTF2F1,GRIPAP1,PML,CTR9,MDFIC,AFF1,TERF1,PURA,NCOA2,TERF2 |
| 1.184e-02 | -4.44 | TADA3 (transcriptional adaptor 3) | protein interactions | 10474 | 69 | 19 | 17029 | 2761 |
CCNC,MAGEH1,KAT2A,HAUS4,ADPGK,SUPT20H,USP22,TAF6L,WDR5,SUPT7L,NUP205,USP5,MBIP,KPNA1,BRD2,LIMK1,TAF5L,TAF12,SGF29 |
| 1.184e-02 | -4.44 | IKBIP (IKBKB interacting protein) | protein interactions | 121457 | 69 | 19 | 17029 | 2761 |
CYFIP1,AGGF1,TRAF7,NDUFB6,PAWR,NCKAP1,SRSF5,CYFIP2,DUSP22,APP,PDCD6,FBXO28,SYNCRIP,EXOC4,NUP62,ABI1,ATP6V0D1,AP2S1,SNAPIN |
| 1.184e-02 | -4.44 | CEP72 (centrosomal protein 72) | protein interactions | 55722 | 69 | 19 | 17029 | 2761 |
CTU2,FGFR1OP,MAPRE1,MCM10,GGA1,DYNLL1,PSMA1,BRCA1,HAUS2,HOMER1,PCM1,SPATA2,CCDC14,ZKSCAN1,ODF2,CEP63,AHCYL1,POC5,DDB1 |
| 1.184e-02 | -4.44 | IFIT3 (interferon induced protein with tetratricopeptide repeats 3) | protein interactions | 3437 | 69 | 19 | 17029 | 2761 |
DDX58,TXN,HNRNPAB,SNRPB,ILF3,SNRPD3,APP,SNRPA,PABPC4,ISG15,RAD23A,HNRNPA2B1,RBMX,YBX1,MAVS,SNRNP70,HNRNPDL,PABPC1,CDC37 |
| 1.185e-02 | -4.44 | GNF2_MBD4 | MSigDB lists | GNF2_MBD4 | 22 | 8 | 17377 | 2626 |
NSA2,DDX5,PFDN5,FAU,SNX2,NACA,PAPOLA,MBD4 |
| 1.185e-02 | -4.44 | GO_REGULATION_OF_ANDROGEN_RECEPTOR_SIGNALING_PATHWAY | MSigDB lists | GO_REGULATION_OF_ANDROGEN_RECEPTOR_SIGNALING_PATHWAY | 22 | 8 | 17377 | 2626 |
BUD31,PIAS2,SMARCA4,DDX5,PRMT2,ARRB2,RNF14,PARK7 |
| 1.185e-02 | -4.44 | BIOCARTA_HER2_PATHWAY | MSigDB lists | BIOCARTA_HER2_PATHWAY | 22 | 8 | 17377 | 2626 |
SHC1,STAT3,MAPK1,HRAS,RAF1,IL6ST,CARM1,MAPK3 |
| 1.185e-02 | -4.44 | GSE12507_PDC_CELL_LINE_VS_IMMATUE_T_CELL_LINE_UP | MSigDB lists | GSE12507_PDC_CELL_LINE_VS_IMMATUE_T_CELL_LINE_UP | 142 | 32 | 17377 | 2626 |
CLSPN,NF1,ACTR3,DBF4,RRM1,NCAPG,KTN1,MIS12,SSR1,RAP1A,MDM2,CCDC50,UTP18,MCM5,BCAP29,RBM15,TMX1,TSHZ1,SRP72,LARS,PRIM2,POLK,NET1,DCTD,ANLN,BBS12,CXXC4,UAP1,SEL1L,KPNA2,GAS2,OSGEPL1 |
| 1.185e-02 | -4.44 | TPR-contain_dom | interpro domains | IPR013026 | 127 | 29 | 18492 | 2768 |
SRP72,RPAP3,NASP,ST13,LONRF3,XAB2,CRNKL1,WDTC1,KLC1,CDC23,TANC1,TTC33,PEX5,CDC16,TTC13,CDC27,TONSL,ZC3H7B,TTC9C,OGT,CTR9,FKBP5,TTC3,CABIN1,ANAPC7,TTC4,TTC17,PPP5C,PDCD11 |
| 1.186e-02 | -4.43 | RUTELLA_RESPONSE_TO_HGF_VS_CSF2RB_AND_IL4_UP | MSigDB lists | RUTELLA_RESPONSE_TO_HGF_VS_CSF2RB_AND_IL4_UP | 386 | 75 | 17377 | 2626 |
PDCD6IP,NQO1,TMX4,HEXB,BCAP31,ZNF804A,APLP2,DECR1,GOT2,ATP13A3,AKR1B1,PLCL2,METTL9,GM2A,METTL1,PPIF,MAPRE2,TIMP2,SEPT9,KLF10,ATP6V0A1,PSMG1,TMEM184C,MAN2A2,RBM47,STAT1,NCOA1,PDXK,LTA4H,CHPF2,CHPT1,ATP6V0E1,GCLM,CDS2,TM9SF4,B4GALT5,HLA-E,GADD45G,SDC2,ASAH1,GTF3A,SLC35B1,NOTCH2,HDDC2,TFRC,GNS,TNS3,SLC31A1,SLC1A4,DAD1,TPST1,ANXA5,CNPY3,MTX2,IMPA2,AMPD2,GALC,PGS1,ICAM2,PRDX1,RDH11,TFEB,SH3BP5,GNA12,SCARB2,ETS2,OAZ2,CTBS,CCDC69,ACAT1,MDH1,RGL1,ATP6V1C1,PLOD3,CD81 |
| 1.186e-02 | -4.43 | Rad51 | pfam domains | PF08423 | 7 | 4 | 17054 | 2545 |
XRCC3,RAD51C,RAD51D,XRCC2 |
| 1.187e-02 | -4.43 | CORO1C (coronin 1C) | protein interactions | 23603 | 93 | 24 | 17029 | 2761 |
MDH2,RAB7A,ACTR3,RAC1,MYH9,CAPZA2,ANLN,TARS,RHOB,RPA1,PAPOLA,MCTS1,SHC1,PIK3R2,RAD23B,MYO18A,DAPK1,ACTB,CORO1A,H3F3A,CDK2,GNAI2,PREB,NUDC |
| 1.187e-02 | -4.43 | SMAD7 (SMAD family member 7) | protein interactions | 4092 | 93 | 24 | 17029 | 2761 |
MBD1,ASH1L,ZNF107,ERBIN,MAPK14,TOLLIP,TTF1,WWP2,FKBP1A,SMAD2,KDM2A,TAB2,UCHL5,AXIN1,AXIN2,DVL1,SMAD1,USP11,SMURF1,ZBTB11,SMAD4,STRAP,PARD3,HDAC2 |
| 1.188e-02 | -4.43 | Semaphorin interactions | REACTOME pathways | R-HSA-373755 | 68 | 19 | 10287 | 1696 |
RHOG,RHOA,PLXNC1,RHOC,RAC1,MYH9,ARHGEF12,PLXNA1,RHOB,PIP5K1C,DPYSL3,CDK5,CDC42,DPYSL2,LIMK1,ITGB1,ROCK1,MYL12B,CFL1 |
| 1.190e-02 | -4.43 | DUF1394 | interpro domains | IPR009828 | 4 | 3 | 18492 | 2768 |
CYFIP1,FAM49B,CYFIP2 |
| 1.190e-02 | -4.43 | Succinyl-CoA_synth-like | interpro domains | IPR016102 | 4 | 3 | 18492 | 2768 |
SUCLG2,SUCLG1,ACLY |
| 1.190e-02 | -4.43 | NSFL1C_SEP_dom_sf | interpro domains | IPR036241 | 4 | 3 | 18492 | 2768 |
UBXN2A,UBXN2B,NSFL1C |
| 1.190e-02 | -4.43 | Ribosomal_L23/L15e_core_dom_sf | interpro domains | IPR012678 | 4 | 3 | 18492 | 2768 |
RPL15,RPS24,RPL23A |
| 1.190e-02 | -4.43 | Small_mtfrase_dom | interpro domains | IPR007848 | 4 | 3 | 18492 | 2768 |
HEMK1,PRMT2,METTL5 |
| 1.190e-02 | -4.43 | PUA_sf | interpro domains | IPR036974 | 4 | 3 | 18492 | 2768 |
NIP7,EIF2D,MCTS1 |
| 1.190e-02 | -4.43 | tRNA_hU_synthase_CS | interpro domains | IPR018517 | 4 | 3 | 18492 | 2768 |
DUS3L,DUS4L,DUS2 |
| 1.190e-02 | -4.43 | Metaxin_GST | interpro domains | IPR033468 | 4 | 3 | 18492 | 2768 |
MTX1,MTX3,MTX2 |
| 1.190e-02 | -4.43 | Porin_dom_sf | interpro domains | IPR023614 | 4 | 3 | 18492 | 2768 |
TOMM40,VDAC1,VDAC2 |
| 1.190e-02 | -4.43 | Luc7-rel | interpro domains | IPR004882 | 4 | 3 | 18492 | 2768 |
LUC7L,LUC7L3,LUC7L2 |
| 1.190e-02 | -4.43 | SEP_domain | interpro domains | IPR012989 | 4 | 3 | 18492 | 2768 |
UBXN2A,UBXN2B,NSFL1C |
| 1.190e-02 | -4.43 | MHC_I_a_C | interpro domains | IPR010579 | 4 | 3 | 18492 | 2768 |
HLA-B,HLA-E,HLA-A |
| 1.190e-02 | -4.43 | tRNA_hU_synthase | interpro domains | IPR001269 | 4 | 3 | 18492 | 2768 |
DUS3L,DUS4L,DUS2 |
| 1.190e-02 | -4.43 | HJURP_C | interpro domains | IPR022102 | 4 | 3 | 18492 | 2768 |
MEF2A,MEF2D,HJURP |
| 1.190e-02 | -4.43 | UAA | interpro domains | IPR013657 | 4 | 3 | 18492 | 2768 |
SLC35B1,SLC35B2,SLC35B4 |
| 1.190e-02 | -4.43 | CoA_ligase | interpro domains | IPR005811 | 4 | 3 | 18492 | 2768 |
SUCLG2,SUCLG1,ACLY |
| 1.190e-02 | -4.43 | SNARE_assoc | interpro domains | IPR032816 | 4 | 3 | 18492 | 2768 |
TMEM41A,VMP1,TMEM41B |
| 1.190e-02 | -4.43 | DUS-like_FMN-bd | interpro domains | IPR035587 | 4 | 3 | 18492 | 2768 |
DUS3L,DUS4L,DUS2 |
| 1.192e-02 | -4.43 | NAGY_STAGA_COMPONENTS_HUMAN | MSigDB lists | NAGY_STAGA_COMPONENTS_HUMAN | 14 | 6 | 17377 | 2626 |
SAP130,TAF5L,TAF6L,TAF12,KAT2A,SUPT7L |
| 1.192e-02 | -4.43 | GO_POSITIVE_REGULATION_OF_HISTONE_H3_K4_METHYLATION | MSigDB lists | GO_POSITIVE_REGULATION_OF_HISTONE_H3_K4_METHYLATION | 14 | 6 | 17377 | 2626 |
CTR9,RTF1,BRCA1,DNMT1,SMAD4,OGT |
| 1.192e-02 | -4.43 | chr10p14 | MSigDB lists | chr10p14 | 14 | 6 | 17377 | 2626 |
PFKFB3,DHTKD1,UPF2,STAM,ZMYND11,OPTN |
| 1.192e-02 | -4.43 | KEGG_GLYCOSAMINOGLYCAN_BIOSYNTHESIS_KERATAN_SULFATE | MSigDB lists | KEGG_GLYCOSAMINOGLYCAN_BIOSYNTHESIS_KERATAN_SULFATE | 14 | 6 | 17377 | 2626 |
B4GALT1,ST3GAL2,B4GALT4,B4GALT3,FUT8,B4GALT2 |
| 1.192e-02 | -4.43 | GO_STAGA_COMPLEX | MSigDB lists | GO_STAGA_COMPLEX | 14 | 6 | 17377 | 2626 |
SAP130,TAF5L,TAF6L,TAF12,KAT2A,SUPT7L |
| 1.192e-02 | -4.43 | PID_S1P_S1P4_PATHWAY | MSigDB lists | PID_S1P_S1P4_PATHWAY | 14 | 6 | 17377 | 2626 |
GNA12,RHOA,CDC42,GNAI2,MAPK1,MAPK3 |
| 1.192e-02 | -4.43 | REACTOME_REPAIR_SYNTHESIS_FOR_GAP_FILLING_BY_DNA_POL_IN_TC_NER | MSigDB lists | REACTOME_REPAIR_SYNTHESIS_FOR_GAP_FILLING_BY_DNA_POL_IN_TC_NER | 14 | 6 | 17377 | 2626 |
RPA2,PCNA,RFC3,POLE,RFC2,RPA1 |
| 1.192e-02 | -4.43 | GO_RETROGRADE_PROTEIN_TRANSPORT_ER_TO_CYTOSOL | MSigDB lists | GO_RETROGRADE_PROTEIN_TRANSPORT_ER_TO_CYTOSOL | 14 | 6 | 17377 | 2626 |
DERL1,SEC61B,SYVN1,RHBDD1,NPLOC4,SEL1L |
| 1.192e-02 | -4.43 | GO_VACUOLAR_PROTON_TRANSPORTING_V_TYPE_ATPASE_COMPLEX | MSigDB lists | GO_VACUOLAR_PROTON_TRANSPORTING_V_TYPE_ATPASE_COMPLEX | 14 | 6 | 17377 | 2626 |
ATP6V0A1,ATP6V0A2,ATP6V0C,ATP6V0B,ATP6V0D1,ATP6V1G1 |
| 1.192e-02 | -4.43 | GO_REGULATION_OF_TRANSLATIONAL_FIDELITY | MSigDB lists | GO_REGULATION_OF_TRANSLATIONAL_FIDELITY | 14 | 6 | 17377 | 2626 |
DTD1,LARS,GATC,IARS,RPS9,IARS2 |
| 1.192e-02 | -4.43 | GRASEMANN_RETINOBLASTOMA_WITH_6P_AMPLIFICATION | MSigDB lists | GRASEMANN_RETINOBLASTOMA_WITH_6P_AMPLIFICATION | 14 | 6 | 17377 | 2626 |
ELOVL5,NUP153,ABCF1,TMX1,RPS10,E2F3 |
| 1.192e-02 | -4.43 | MODULE_429 | MSigDB lists | MODULE_429 | 14 | 6 | 17377 | 2626 |
RPL37,RPL32,WDR5,RPLP2,TMEM109,LDHB |
| 1.192e-02 | -4.43 | GO_NBAF_COMPLEX | MSigDB lists | GO_NBAF_COMPLEX | 14 | 6 | 17377 | 2626 |
SMARCA4,SS18L1,ARID1A,SMARCE1,ARID1B,SMARCD1 |
| 1.192e-02 | -4.43 | GO_NEGATIVE_REGULATION_OF_DNA_DEPENDENT_DNA_REPLICATION | MSigDB lists | GO_NEGATIVE_REGULATION_OF_DNA_DEPENDENT_DNA_REPLICATION | 14 | 6 | 17377 | 2626 |
CHEK2,SMC3,ZNF830,BLM,TERF1,TERF2 |
| 1.192e-02 | -4.43 | REACTOME_TGF_BETA_RECEPTOR_SIGNALING_IN_EMT_EPITHELIAL_TO_MESENCHYMAL_TRANSITION | MSigDB lists | REACTOME_TGF_BETA_RECEPTOR_SIGNALING_IN_EMT_EPITHELIAL_TO_MESENCHYMAL_TRANSITION | 14 | 6 | 17377 | 2626 |
TGFB1,FKBP1A,RHOA,SMURF1,RPS27A,PARD3 |
| 1.192e-02 | -4.43 | SABATES_COLORECTAL_ADENOMA_SIZE_UP | MSigDB lists | SABATES_COLORECTAL_ADENOMA_SIZE_UP | 14 | 6 | 17377 | 2626 |
FBXL6,GART,STX16,SLC20A1,NKD2,LRRC14 |
| 1.192e-02 | -4.43 | GO_CYTOKINETIC_PROCESS | MSigDB lists | GO_CYTOKINETIC_PROCESS | 14 | 6 | 17377 | 2626 |
KIF23,RACGAP1,AURKB,CNTROB,RHOA,SNX18 |
| 1.192e-02 | -4.43 | GO_MANNOSIDASE_ACTIVITY | MSigDB lists | GO_MANNOSIDASE_ACTIVITY | 14 | 6 | 17377 | 2626 |
MAN2A2,MAN2B1,EDEM2,MANBA,MAN1B1,MAN1A1 |
| 1.196e-02 | -4.43 | p38MAPK events | REACTOME pathways | R-HSA-171007 | 13 | 6 | 10287 | 1696 |
KRAS,NRAS,RALB,MAPKAPK3,MAPK14,HRAS |
| 1.197e-02 | -4.43 | GO_REGULATION_OF_ESTABLISHMENT_OF_PLANAR_POLARITY | MSigDB lists | GO_REGULATION_OF_ESTABLISHMENT_OF_PLANAR_POLARITY | 110 | 26 | 17377 | 2626 |
RHOA,CELSR2,PSMA8,RAC1,PSMB7,PSMA1,ZNRF3,PSMB9,PSMD9,PSMB3,FZD6,PSMC4,PSMD2,PSMD1,PSMA6,CDC42,RPS27A,PSMD3,PSMD8,AP2B1,DVL1,SMURF1,ARRB2,PSMC1,AP2S1,DVL2 |
| 1.197e-02 | -4.43 | GO_DEACETYLASE_ACTIVITY | MSigDB lists | GO_DEACETYLASE_ACTIVITY | 54 | 15 | 17377 | 2626 |
BRMS1,ATXN3,CHD3,HDAC7,MTA1,MTA2,RCOR1,SIRT2,AMDHD2,RBBP4,MBD3,SAP30L,ARID4A,HDAC2,SAP30 |
| 1.198e-02 | -4.42 | nuclear-transcribed mRNA catabolic process, exonucleolytic | biological process | GO:0000291 | 35 | 11 | 17256 | 2622 |
EXOSC6,EXOSC7,POLR2G,LSM6,NT5C3B,EXOSC1,DCP1A,CNOT6,EXOSC9,PATL1,EDC3 |
| 1.198e-02 | -4.42 | establishment of spindle localization | biological process | GO:0051293 | 35 | 11 | 17256 | 2622 |
MAP4,ARHGEF2,MYH9,NUSAP1,SPDL1,NDE1,MCPH1,ESPL1,SPAG5,SAPCD2,DCTN1 |
| 1.198e-02 | -4.42 | human chr6q24.1 | chromosome location | human chr6q24.1 | 19 | 6 | 26185 | 2809 |
HEBP2,HECA,CITED2,REPS1,CCDC28A,ABRACL |
| 1.200e-02 | -4.42 | DUSP-like_sf | interpro domains | IPR035927 | 7 | 4 | 18492 | 2768 |
USP20,USP11,USP48,USP32 |
| 1.200e-02 | -4.42 | RecA_ATP-bd | interpro domains | IPR020588 | 7 | 4 | 18492 | 2768 |
RAD51C,XRCC3,RAD51D,XRCC2 |
| 1.200e-02 | -4.42 | AP_complex_ssu | interpro domains | IPR016635 | 7 | 4 | 18492 | 2768 |
AP1S1,AP3S1,AP3S2,AP2S1 |
| 1.200e-02 | -4.42 | DNA_recomb/repair_Rad51_C | interpro domains | IPR013632 | 7 | 4 | 18492 | 2768 |
RAD51C,XRCC3,RAD51D,XRCC2 |
| 1.200e-02 | -4.42 | Pept_C19_DUSP | interpro domains | IPR006615 | 7 | 4 | 18492 | 2768 |
USP20,USP11,USP48,USP32 |
| 1.200e-02 | -4.42 | cleavage furrow | cellular component | GO:0032154 | 55 | 15 | 18223 | 2701 |
RAB21,PDXP,RHOA,RHOC,CEP55,ITGB1,MYH9,RACGAP1,SEPT7,ICAM2,NDE1,MEN1,RAB11A,RHOB,MASTL |
| 1.201e-02 | -4.42 | PID_CMYB_PATHWAY | MSigDB lists | PID_CMYB_PATHWAY | 84 | 21 | 17377 | 2626 |
PPP3CA,H2AFZ,NRAS,COPA,BIRC3,CASP6,KRAS,SND1,CCNB1,UBE2I,ETS1,TRIM28,MAT2A,ETS2,TAB2,HIPK2,CDKN1B,BCL2,HRAS,CBX4,CDKN2A |
| 1.201e-02 | -4.42 | GSE19888_ADENOSINE_A3R_ACT_VS_A3R_ACT_WITH_A3R_INH_PRETREATMENT_IN_MAST_CELL_DN | MSigDB lists | GSE19888_ADENOSINE_A3R_ACT_VS_A3R_ACT_WITH_A3R_INH_PRETREATMENT_IN_MAST_CELL_DN | 186 | 40 | 17377 | 2626 |
DDX58,COX15,PKP4,NUP188,RAE1,TOR3A,CDT1,EIF2AK4,IP6K2,CENPJ,ZCCHC2,POP7,FUT8,ZNF335,MAVS,RLIM,SAP30,MLST8,ENPP4,MIOS,ANKRD37,TSTA3,ELL2,MRS2,GBA,SLC25A22,PLEKHM3,EML4,ISG15,RPA1,ANKZF1,ATP1A1,CDKN2AIPNL,CCDC6,STAT1,BAZ1B,TATDN1,WDR62,FAM208A,CCDC59 |
| 1.201e-02 | -4.42 | GO_RESPONSE_TO_REACTIVE_OXYGEN_SPECIES | MSigDB lists | GO_RESPONSE_TO_REACTIVE_OXYGEN_SPECIES | 186 | 40 | 17377 | 2626 |
TXN,NQO1,PPP1R15B,PRKAA1,CYCS,ETS1,PARK7,PDK2,MDM2,PDCD10,CCNA2,SHC1,DNM2,AKR1B1,BCL2,PTPRK,PPIF,BAK1,PLK3,TNFAIP3,NET1,LDHA,KLF6,MTR,PRDX1,RHOB,FAS,CAT,KPNA4,PRDX3,STAT6,PRDX5,MPV17,ADAM9,PKD2,MAP3K5,PPP5C,CDK2,HDAC2,EGLN1 |
| 1.201e-02 | -4.42 | GSE3039_ALPHABETA_CD8_TCELL_VS_B2_BCELL_UP | MSigDB lists | GSE3039_ALPHABETA_CD8_TCELL_VS_B2_BCELL_UP | 186 | 40 | 17377 | 2626 |
HECA,CDS2,LIME1,CYLD,RPS6KA1,VAV2,CIB1,PMS2,TATDN3,AP3M2,TOP2B,ABCB10,ZNF518A,BZW2,RAPGEF6,MAN1A1,UBXN2A,ADD3,FBXL6,NUP210,ANP32A,ABCD1,ARID4A,MLST8,TSPYL4,FRAT2,ARID1A,CYFIP2,ARMC8,STX16,EIF3A,KRIT1,UBXN2B,ARAP1,VCPIP1,SCARB1,AKNA,MYO9A,SLC22A23,PRPF4B |
| 1.201e-02 | -4.42 | GSE45365_WT_VS_IFNAR_KO_CD8A_DC_DN | MSigDB lists | GSE45365_WT_VS_IFNAR_KO_CD8A_DC_DN | 186 | 40 | 17377 | 2626 |
PARP12,PLXNC1,TRIP12,TAP1,ARID5A,PLAGL2,BRAP,UBE2Z,POMP,PSEN1,RBM4,MXD1,GTF2F1,CDKN2C,ABL2,DDX56,SAR1A,ARHGEF2,JOSD1,RNF19A,TP53BP2,TALDO1,STAT3,LPCAT1,CDC37,TNFAIP3,ELL2,SNRPB,PFKFB3,PRPF3,LUC7L,DDX39A,PAF1,VEZF1,CSNK1G1,TICAM1,H3F3A,PSMC1,APOL2,ZC3HAV1 |
| 1.201e-02 | -4.42 | GSE17721_LPS_VS_GARDIQUIMOD_12H_BMDC_UP | MSigDB lists | GSE17721_LPS_VS_GARDIQUIMOD_12H_BMDC_UP | 186 | 40 | 17377 | 2626 |
POU3F2,DNAJC2,GNPNAT1,TPX2,PXMP2,CHAC2,PMVK,IFT27,COPG2,UBLCP1,RAD23A,CLIC4,PTEN,TBC1D22A,NOC2L,PDCD2,H2AFY,RPAP1,AP2B1,TAGLN2,RBM15,UBE2M,CDC37,GUK1,PGS1,HTATIP2,LRRC8A,TOR1AIP2,EXOSC9,BMS1,RAB22A,SMAP2,HSPA1B,PDCD6,KEAP1,GALNT10,RNASEL,IGBP1,USP53,NRBP1 |
| 1.201e-02 | -4.42 | GSE24081_CONTROLLER_VS_PROGRESSOR_HIV_SPECIFIC_CD8_TCELL_DN | MSigDB lists | GSE24081_CONTROLLER_VS_PROGRESSOR_HIV_SPECIFIC_CD8_TCELL_DN | 186 | 40 | 17377 | 2626 |
PARP12,TMBIM4,TRIP10,GPBP1L1,C1orf112,SMC6,ZNF267,XPO7,RAB11A,C1GALT1,HOMER1,RPN1,GART,EIF2S2,ARPC5,ATG3,DNAAF2,PHF14,MAVS,RNASEH2A,TMX1,SRPK2,VOPP1,RPAP3,RHOA,EID1,KIAA0040,RRM2,EAF2,RDH11,KEAP1,RBL1,CEP55,STAT1,AP1S1,UBE2C,CDK2,USP53,RTN3,N4BP2L2 |
| 1.201e-02 | -4.42 | GSE8621_UNSTIM_VS_LPS_PRIMED_AND_LPS_STIM_MACROPHAGE_DN | MSigDB lists | GSE8621_UNSTIM_VS_LPS_PRIMED_AND_LPS_STIM_MACROPHAGE_DN | 186 | 40 | 17377 | 2626 |
CCDC93,USP7,CTU2,HSPH1,TMEM109,ALKBH5,MED13L,IP6K2,XPO7,TCF19,FAM8A1,PIP4K2A,TRIM65,ANKRD26,MTMR4,GMEB1,BCL2,RNF169,ANKLE2,ABHD2,HARS,AACS,USP42,WDHD1,UHRF1BP1,MEF2D,UBE4B,PDE3B,IWS1,SLCO4A1,CACNB1,RAD18,SEC61A1,SCAP,CERS6,ACLY,AKNA,MAP3K5,CBX4,TMEM131 |
| 1.201e-02 | -4.42 | GSE17721_CTRL_VS_GARDIQUIMOD_12H_BMDC_DN | MSigDB lists | GSE17721_CTRL_VS_GARDIQUIMOD_12H_BMDC_DN | 186 | 40 | 17377 | 2626 |
PKP4,DHPS,SLC2A1,TBC1D13,INO80E,LYN,REPS1,SRXN1,RAD23A,LIN9,ANKRD26,PA2G4,SHC1,CBWD2,PPIG,POP7,TAGLN2,CITED2,TIPARP,LRRC59,NAA35,UBE2M,HTRA2,TXNL1,USO1,DPM1,ELL2,TIMMDC1,NET1,NSUN2,WBP2,LUC7L,GOSR1,CCT8,PI4K2A,DGCR8,PRMT7,NMD3,CDKN2A,PFKP |
| 1.202e-02 | -4.42 | REACTOME_INTERFERON_SIGNALING | MSigDB lists | REACTOME_INTERFERON_SIGNALING | 153 | 34 | 17377 | 2626 |
DDX58,NUP188,RAE1,NUP54,IRF3,IP6K2,NUP205,HLA-A,PTPN2,IRF4,NUP210,SP100,EIF4A3,PIN1,NUP107,NUP153,NUP85,SEH1L,NUP155,EIF4G2,ISG15,IRF5,MAPK3,HLA-B,KPNA1,KPNA4,JAK1,RPS27A,PML,STAT1,KPNA2,NUP62,RNASEL,AAAS |
| 1.203e-02 | -4.42 | DCTPP1 (dCTP pyrophosphatase 1) | protein interactions | 79077 | 33 | 11 | 17029 | 2761 |
PLK1,PCNA,GNPDA1,WDYHV1,NOA1,WDR4,CTPS1,CHMP4B,CRY2,APP,RAD23A |
| 1.203e-02 | -4.42 | CHST8 (carbohydrate sulfotransferase 8) | protein interactions | 64377 | 33 | 11 | 17029 | 2761 |
NOP9,JMJD4,RBM23,TOR3A,FAM3C,MRS2,CHCHD2,EDEM2,FBL,TMED2,TMEM160 |
| 1.203e-02 | -4.42 | KDM6A (lysine demethylase 6A) | protein interactions | 7403 | 33 | 11 | 17029 | 2761 |
FNTA,PTEN,PROSER1,SMARCA4,WDR82,PPP6R3,KMT2C,WDR5,N4BP2,EYA2,MSH6 |
| 1.203e-02 | -4.42 | CENPQ (centromere protein Q) | protein interactions | 55166 | 33 | 11 | 17029 | 2761 |
PLK1,DGCR8,RPS14,SEC24C,CENPT,CCNL2,VPS4A,CENPM,APP,CENPU,SUPT16H |
| 1.203e-02 | -4.42 | HIST1H4F (histone cluster 1 H4 family member f) | protein interactions | 8361 | 33 | 11 | 17029 | 2761 |
H2AFZ,UCHL5,MECP2,CUL3,SMARCA4,H3F3A,MCM2,ASF1B,CHAF1A,CBX3,CAND1 |
| 1.203e-02 | -4.42 | Smc3 (structural maintenance of chromosomes 3) | protein interactions | 13006 | 33 | 11 | 17029 | 2761 |
FYTTD1,EIF5A,COA3,TXN,CDCA5,PDS5B,KIF22,SMC2,TAF12,PDF,USP13 |
| 1.203e-02 | -4.42 | HARS2 (histidyl-tRNA synthetase 2, mitochondrial) | protein interactions | 23438 | 33 | 11 | 17029 | 2761 |
SDHB,PRKAB1,GORASP1,AGTRAP,HARS,GRSF1,MRPL12,FUS,ORC1,MRPL21,NDUFS7 |
| 1.203e-02 | -4.42 | MAP3K10 (mitogen-activated protein kinase kinase kinase 10) | protein interactions | 4294 | 33 | 11 | 17029 | 2761 |
ABL2,KIF3B,HGS,CDC42,RAC1,RACGAP1,KIFAP3,MAPK14,SMURF1,MAPK1,TUBB |
| 1.203e-02 | -4.42 | WDR6 (WD repeat domain 6) | protein interactions | 11180 | 33 | 11 | 17029 | 2761 |
MEX3C,KMT2E,FTSJ1,CUL3,TMEM216,TIA1,STK11,CDC25B,DMWD,BRCA1,CDC37 |
| 1.203e-02 | -4.42 | SDAD1 (SDA1 domain containing 1) | protein interactions | 55153 | 33 | 11 | 17029 | 2761 |
NSA2,NAP1L1,ZNF512,RPS14,RBM34,MECP2,NOC2L,GTPBP4,TARDBP,FBL,NMD3 |
| 1.203e-02 | -4.42 | EDF1 (endothelial differentiation related factor 1) | protein interactions | 8721 | 33 | 11 | 17029 | 2761 |
EWSR1,DHX29,MAPK6,HNRNPF,IMPDH1,DNAJB1,RNASEH2A,CREB1,UBE2I,SOX4,ATF2 |
| 1.207e-02 | -4.42 | deacetylase activity | molecular function | GO:0019213 | 58 | 16 | 17224 | 2647 |
MTA2,MIER1,RCOR1,MIER2,SIRT2,AMDHD2,MBD3,BRMS1,CHD3,MTA1,HDAC7,RBBP4,SAP30L,HDAC2,ARID4A,SAP30 |
| 1.208e-02 | -4.42 | GSE2706_LPS_VS_R848_AND_LPS_8H_STIM_DC_UP | MSigDB lists | GSE2706_LPS_VS_R848_AND_LPS_8H_STIM_DC_UP | 175 | 38 | 17377 | 2626 |
ADD1,KIAA0100,CCM2,TMEM109,RRM1,ABCB10,HAUS4,NHLRC3,DOCK11,TWF2,SLC25A43,MAD2L2,LMNA,DDRGK1,PHC2,ANKLE1,DECR1,RALB,SRSF4,SLC44A1,GLE1,TRIM14,PPP1R21,KIAA0930,KDM1B,PTTG1IP,SHCBP1,MYO1F,VPS26B,ARNTL,NFIL3,PPA2,STAT1,RBMS1,NCOA1,RGL1,LTA4H,ANAPC4 |
| 1.208e-02 | -4.42 | GSE1925_CTRL_VS_24H_IFNG_STIM_MACROPHAGE_DN | MSigDB lists | GSE1925_CTRL_VS_24H_IFNG_STIM_MACROPHAGE_DN | 175 | 38 | 17377 | 2626 |
MTX3,GNPNAT1,SCAMP3,RHOC,TCF3,SLC39A13,EBNA1BP2,S1PR2,GTPBP3,MRPL50,CLUAP1,CS,CNPY4,SLC27A4,ABCC5,ATP6V1G1,CCT2,TRIM8,SNRPB,DRAP1,DENND1B,NUDT4,VDAC2,SREK1,DCUN1D5,CBFA2T2,PWWP2B,NRM,FTSJ1,SLC25A19,BAZ1B,PPP6R2,PLOD3,TFDP2,TSTD2,NAA60,TUBB,RHEBL1 |
| 1.208e-02 | -4.42 | GSE15330_HSC_VS_LYMPHOID_PRIMED_MULTIPOTENT_PROGENITOR_DN | MSigDB lists | GSE15330_HSC_VS_LYMPHOID_PRIMED_MULTIPOTENT_PROGENITOR_DN | 175 | 38 | 17377 | 2626 |
FAM129A,PTTG1,RRM1,CDCA8,TPX2,FKBP2,AP3S1,NCAPG,REEP5,MFSD10,CALM2,RPA2,CCDC50,MCM5,RRBP1,LPIN2,SEPT11,NDUFB9,MTPN,MYO5A,TACC3,SAP30,RFC3,NUDT4,MKI67,HTATIP2,KIF11,ASF1B,HMGN2,MYO1F,AHNAK,PSMD8,CEP55,ITGB1,COX5A,ATF6,FKBP5,CHPT1 |
| 1.209e-02 | -4.42 | GO_POSITIVE_REGULATION_OF_APOPTOTIC_SIGNALING_PATHWAY | MSigDB lists | GO_POSITIVE_REGULATION_OF_APOPTOTIC_SIGNALING_PATHWAY | 164 | 36 | 17377 | 2626 |
CYLD,TRAF7,NF1,DYNLL1,MAGED1,PLAGL2,BCL2L1,BCAP31,PARK7,APOPT1,MOAP1,PTPN2,TFAP4,PTEN,SIAH1,SIVA1,BCL2,TP53BP2,HTRA2,PPIF,BAK1,NCK1,BCLAF1,MCL1,PRKRA,DAPK3,FADD,FAS,TFDP1,PPP3R1,E2F1,PML,YWHAZ,CLU,YWHAH,FAF1 |
| 1.209e-02 | -4.42 | GSE19888_CTRL_VS_A3R_INHIBITOR_TREATED_MAST_CELL_DN | MSigDB lists | GSE19888_CTRL_VS_A3R_INHIBITOR_TREATED_MAST_CELL_DN | 164 | 36 | 17377 | 2626 |
UBL3,ZBTB10,HECA,PNISR,NF1,SRGN,MED13L,RGS2,DUSP22,FOXO3,JMY,PAIP2,GNS,APLP2,RAB21,NAA50,PIK3IP1,F2R,CTDSP2,SOCS5,USO1,TNFAIP3,RB1CC1,DCAF8,RPL38,PNPLA8,PDE3B,PICALM,PFDN5,TPD52L2,VEZF1,ARAP1,PIAS2,ITGB1,N4BP2L2,ZSWIM6 |
| 1.211e-02 | -4.41 | Trans-sulfuration pathway | WikiPathways | WP2333 | 10 | 5 | 5312 | 837 |
MAT2B,GCLM,AHCY,MTR,DNMT1 |
| 1.212e-02 | -4.41 | negative regulation of type I interferon production | biological process | GO:0032480 | 49 | 14 | 17256 | 2622 |
DDX58,OTUD5,CYLD,TNFAIP3,RPS27A,PIN1,NLRC5,MAVS,IRF3,RNF135,YY1,NPLOC4,ISG15,PCBP2 |
| 1.212e-02 | -4.41 | response to interleukin-12 | biological process | GO:0070671 | 49 | 14 | 17256 | 2622 |
HNRNPA2B1,MIF,JAK1,CDC42,CAPZA1,HNRNPF,PITPNA,CNN2,IL12RB1,ARF1,TALDO1,HNRNPDL,CFL1,PDCD4 |
| 1.212e-02 | -4.41 | tRNA aminoacylation for protein translation | biological process | GO:0006418 | 49 | 14 | 17256 | 2622 |
FARSA,KARS,EPRS,LARS,IARS,HARS,MRPL39,QARS,PPA2,IARS2,POLG2,PPA1,TARS,CARS2 |
| 1.212e-02 | -4.41 | V$HIF1_Q3 | MSigDB lists | V$HIF1_Q3 | 214 | 45 | 17377 | 2626 |
RECQL,ZBTB10,MAX,ZBTB37,SRSF6,SCYL1,AGPAT1,NANS,STMN1,KTN1,TFRC,NRF1,PTEN,UTP18,MEA1,YBX1,BCL2,PIK3IP1,CITED2,CNPY3,ZNF800,PABPC1,RNF5,AMPD2,ERF,LDHA,E2F3,SRSF5,KDM3A,FKBP3,SRSF1,DOT1L,HMGN2,DERL1,PTPRF,GOLGA4,ARNTL,NFIL3,ATXN2L,RUVBL2,NR2F2,BRWD3,USF2,LRP8,GCSH |
| 1.212e-02 | -4.41 | ANXA7 (annexin A7) | protein interactions | 310 | 138 | 33 | 17029 | 2761 |
RPS2,ATXN3,HMGXB3,WDR18,TKT,ATP5F1B,PKM,PCBP1,KIF11,PRKACA,EXT2,GNB2,PARK7,NMT2,RPA1,FLAD1,PLD3,PDCD6,QARS,UCHL5,HADHB,SRI,MSH2,KMT2B,ACTB,TAF5L,DVL1,GPI,RBBP4,UBE3C,COPS6,MOB1A,FAF1 |
| 1.218e-02 | -4.41 | GO_ANATOMICAL_STRUCTURE_HOMEOSTASIS | MSigDB lists | GO_ANATOMICAL_STRUCTURE_HOMEOSTASIS | 265 | 54 | 17377 | 2626 |
POLA2,NPHP4,ADD1,RAC1,SMC6,TERF2IP,RPA2,HOMER1,PCNA,SP100,PTPN11,AKR1B1,BCL2,PTGES3,CORO1A,F2R,LPCAT1,STRAP,DRAM2,TERF2,ERCC1,RFC3,PRIM2,RAB7A,PRKDC,LDB1,KRAS,DCLRE1C,ADRB2,CHMP2B,GAR1,RFC2,PRDX1,BBS12,NCDN,PRIM1,XRCC5,RPA1,GNAS,RAD51C,UPF1,POLE,NSMCE2,PRDX5,ITGB1,ACTB,CHMP4B,XRCC3,STK11,TRIM32,ZNF830,POT1,TERF1,RAD51D |
| 1.219e-02 | -4.41 | MORI_SMALL_PRE_BII_LYMPHOCYTE_UP | MSigDB lists | MORI_SMALL_PRE_BII_LYMPHOCYTE_UP | 79 | 20 | 17377 | 2626 |
WASF2,POU2AF1,TCF12,ADAM10,BTG2,MECP2,TRIM11,CERK,FRAT2,B4GALT1,RGS2,ECH1,RBM17,IRF4,RB1,C1GALT1,DUSP11,SLAIN1,ARL5A,MYO5A |
| 1.221e-02 | -4.41 | CDK5 (cyclin dependent kinase 5) | protein interactions | 1020 | 133 | 32 | 17029 | 2761 |
SARNP,PPP1R2,MEF2A,GLUD1,CCNB1,PSEN1,SCYL2,APP,PIP5K1C,PTPN2,CDK5,RB1,SUB1,PCNA,CCNA2,SEPT11,CDKN1B,CDC25B,CABLES2,PIKFYVE,HTRA2,CDC37,CCT2,EZR,GORASP2,SEPT7,CCT8,SH3GLB1,CABLES1,C2CD5,PURA,CSNK1D |
| 1.222e-02 | -4.40 | B cell receptor signaling pathway | KEGG pathways | ko04662 | 70 | 19 | 7161 | 1149 |
PPP3CA,NRAS,RAF1,AKT2,RAC1,VAV2,NFATC2,KRAS,PPP3CB,LYN,MAP2K2,MAPK3,VAV1,NFATC3,PIK3R2,PPP3R1,MAPK1,CD81,HRAS |
| 1.222e-02 | -4.40 | B cell receptor signaling pathway | KEGG pathways | hsa04662 | 70 | 19 | 7161 | 1149 |
PPP3CA,NRAS,RAF1,AKT2,RAC1,VAV2,NFATC2,KRAS,PPP3CB,LYN,MAP2K2,MAPK3,VAV1,NFATC3,PIK3R2,PPP3R1,MAPK1,CD81,HRAS |
| 1.223e-02 | -4.40 | GO_PHOSPHOPROTEIN_BINDING | MSigDB lists | GO_PHOSPHOPROTEIN_BINDING | 59 | 16 | 17377 | 2626 |
CSNK1G2,RB1,CACNB1,ACP2,SHC1,PRKCSH,PIN1,CSNK1G1,PKD2,THRAP3,MAPK1,LYN,CBX4,PHF6,CSNK1D,MAPK3 |
| 1.223e-02 | -4.40 | MYLLYKANGAS_AMPLIFICATION_HOT_SPOT_3 | MSigDB lists | MYLLYKANGAS_AMPLIFICATION_HOT_SPOT_3 | 4 | 3 | 17377 | 2626 |
TCF12,BLM,PML |
| 1.223e-02 | -4.40 | BASSO_HAIRY_CELL_LEUKEMIA_UP | MSigDB lists | BASSO_HAIRY_CELL_LEUKEMIA_UP | 4 | 3 | 17377 | 2626 |
PAWR,TNFAIP8,TRAF5 |
| 1.223e-02 | -4.40 | Ser/Thr_kinase_AS | interpro domains | IPR008271 | 308 | 61 | 18492 | 2768 |
RAF1,RPS6KA1,PRKAA1,TRIO,CSNK2A1,CDK13,EIF2AK4,CDK11B,CSNK1A1,PRKACA,CDK5,PRKD3,GRK2,NEK6,DAPK1,MAST2,MAP3K14,CDK12,PHKG2,CSNK1G3,CAMK2G,SRPK2,PLK3,PDPK1,PLK1,CSNK1G2,ULK3,MAPKAPK3,NEK7,AKT2,PBK,TAOK1,MAP4K4,TLK1,EIF2AK1,PKMYT1,AURKB,CDK11A,STK17B,MARK2,MAP2K2,DAPK3,MAPK3,MASTL,MAP3K4,MKNK1,NEK1,CLK3,CSNK1G1,HIPK2,STK38,MAPK6,STK11,CHEK2,ROCK1,MAP3K5,MAPK1,CDK2,HIPK3,CSNK1D,PRPF4B |
| 1.223e-02 | -4.40 | negative regulation of protein localization to plasma membrane | biological process | GO:1903077 | 22 | 8 | 17256 | 2622 |
TGFB1,PPP2R5A,CSK,GOPC,BCL2L1,PICALM,NUMB,TMBIM1 |
| 1.223e-02 | -4.40 | maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) | biological process | GO:0000466 | 22 | 8 | 17256 | 2622 |
KRI1,UTP20,EXOSC9,EXOSC7,RRS1,PDCD11,FTSJ3,RPSA |
| 1.224e-02 | -4.40 | cardiolipin metabolic process | biological process | GO:0032048 | 14 | 6 | 17256 | 2622 |
PDXP,TAZ,LCLAT1,PGS1,MECP2,HADHB |
| 1.224e-02 | -4.40 | oligosaccharide catabolic process | biological process | GO:0009313 | 14 | 6 | 17256 | 2622 |
MAN2B1,MANBA,GM2A,NEU1,CTBS,HEXB |
| 1.224e-02 | -4.40 | CDP-diacylglycerol metabolic process | biological process | GO:0046341 | 14 | 6 | 17256 | 2622 |
AGPAT3,CDS2,CDIPT,AGPAT2,LCLAT1,AGPAT1 |
| 1.226e-02 | -4.40 | MODULE_392 | MSigDB lists | MODULE_392 | 18 | 7 | 17377 | 2626 |
RAD51C,KPNA2,TCOF1,RPL35,H2AFZ,H2AFX,MSH2 |
| 1.226e-02 | -4.40 | SMID_BREAST_CANCER_LUMINAL_A_DN | MSigDB lists | SMID_BREAST_CANCER_LUMINAL_A_DN | 18 | 7 | 17377 | 2626 |
ANP32E,TTLL4,LRP8,TPX2,CDCA3,MYBL2,CDCA8 |
| 1.226e-02 | -4.40 | BIOCARTA_TEL_PATHWAY | MSigDB lists | BIOCARTA_TEL_PATHWAY | 18 | 7 | 17377 | 2626 |
PPP2CA,KRAS,RB1,BCL2,TERF1,POLR2A,XRCC5 |
| 1.226e-02 | -4.40 | GO_POLY_PURINE_TRACT_BINDING | MSigDB lists | GO_POLY_PURINE_TRACT_BINDING | 18 | 7 | 17377 | 2626 |
TIA1,ATXN1,SYNCRIP,EIF4A3,PATL1,PABPC1,PABPC4 |
| 1.226e-02 | -4.40 | PID_BETA_CATENIN_DEG_PATHWAY | MSigDB lists | PID_BETA_CATENIN_DEG_PATHWAY | 18 | 7 | 17377 | 2626 |
CUL1,DVL1,CSNK1A1,AXIN1,DVL2,CSNK1D,AXIN2 |
| 1.226e-02 | -4.40 | REACTOME_INHIBITION_OF_THE_PROTEOLYTIC_ACTIVITY_OF_APC_C_REQUIRED_FOR_THE_ONSET_OF_ANAPHASE_BY_MITOTIC_SPINDLE_CHECKPOINT_COMPONENTS | MSigDB lists | REACTOME_INHIBITION_OF_THE_PROTEOLYTIC_ACTIVITY_OF_APC_C_REQUIRED_FOR_THE_ONSET_OF_ANAPHASE_BY_MITOTIC_SPINDLE_CHECKPOINT_COMPONENTS | 18 | 7 | 17377 | 2626 |
ANAPC2,ANAPC7,CDC16,CDC23,CDC27,UBE2C,ANAPC4 |
| 1.226e-02 | -4.40 | YIH_RESPONSE_TO_ARSENITE_C2 | MSigDB lists | YIH_RESPONSE_TO_ARSENITE_C2 | 18 | 7 | 17377 | 2626 |
SP3,TCF12,MCL1,ATF2,CAST,TANK,FADD |
| 1.226e-02 | -4.40 | HOLLEMAN_ASPARAGINASE_RESISTANCE_ALL_UP | MSigDB lists | HOLLEMAN_ASPARAGINASE_RESISTANCE_ALL_UP | 18 | 7 | 17377 | 2626 |
CCDC69,EIF3K,TAP2,NPHP4,MICAL3,RPL11,RPL6 |
| 1.226e-02 | -4.40 | HONRADO_BREAST_CANCER_BRCA1_VS_BRCA2 | MSigDB lists | HONRADO_BREAST_CANCER_BRCA1_VS_BRCA2 | 18 | 7 | 17377 | 2626 |
BCL2,MDM2,CCNA2,CCNB1,BIRC5,CDKN2A,MKI67 |
| 1.226e-02 | -4.40 | GO_S_ADENOSYLMETHIONINE_METABOLIC_PROCESS | MSigDB lists | GO_S_ADENOSYLMETHIONINE_METABOLIC_PROCESS | 18 | 7 | 17377 | 2626 |
MAT2B,AHCY,AHCYL1,DNMT1,MRI1,AMD1,MAT2A |
| 1.228e-02 | -4.40 | antigen processing and presentation of peptide antigen via MHC class I | biological process | GO:0002474 | 94 | 23 | 17256 | 2622 |
PSMA8,HLA-E,TAP1,PSMB7,PSMA1,ITGB5,PSMB9,PSMD9,BCAP31,PSMB3,HLA-A,PSMC4,SEC31A,HLA-B,PSMD2,PSMD1,PSMA6,PSMD8,SEC24C,SNAP23,PSMD3,TAP2,PSMC1 |
| 1.228e-02 | -4.40 | RNA modification | biological process | GO:0009451 | 147 | 33 | 17256 | 2622 |
SEPHS2,CTU2,METTL1,NOP2,TRMT6,NSUN2,METTL2A,ALKBH5,ELP4,GAR1,PARN,METTL3,GTPBP3,RBM47,DUS3L,DUS4L,THADA,ELP5,METTL14,CMTR2,TRMU,WDR4,TYW5,LRPPRC,DUS2,FTSJ1,TRMT10B,OSGEPL1,FBL,MRM3,NSUN4,FTSJ3,MRM2 |
| 1.231e-02 | -4.40 | ITSN1 (intersectin 1) | protein interactions | 6453 | 113 | 28 | 17029 | 2761 |
PLK1,CYTH1,TK1,PDCD6IP,TRIM8,SCOC,ARFIP2,AGFG1,SPDL1,REPS1,PICALM,NECAP2,PFDN5,WAS,ASAP2,RAD18,CDC42,SETD3,SNAP23,MAPK6,DNM2,AP2B1,RNASEH2A,TFG,IGBP1,AP2S1,HRAS,GCC1 |
| 1.231e-02 | -4.40 | FANCA (Fanconi anemia complementation group A) | protein interactions | 2175 | 113 | 28 | 17029 | 2761 |
CHTF18,PRKAA1,RMI2,TOP3A,SMARCA4,KRAS,BRCA1,DNAJB1,ATP5F1B,MEN1,BLM,FANCE,RMI1,GNB2,RPA1,FANCL,MKNK1,PCNA,DUS4L,MCM5,FAAP100,MSH2,IARS2,XRCC3,RBPJ,CAPN1,RAD51D,SPTAN1 |
| 1.231e-02 | -4.40 | CDC23 (cell division cycle 23) | protein interactions | 8697 | 113 | 28 | 17029 | 2761 |
SLC39A9,HEMK1,CDT1,C16orf87,RAC1,ANAPC2,GORASP2,USP22,CDC23,VKORC1,EDRF1,MAPK3,RAD54B,OPTN,FBXO5,NAP1L1,CDC16,CDC27,SIAH1,ANAPC7,NAP1L4,FBL,COIL,ANAPC4,APOL1,BYSL,CDC5L,RBM15B |
| 1.232e-02 | -4.40 | KEGG_B_CELL_RECEPTOR_SIGNALING_PATHWAY | MSigDB lists | KEGG_B_CELL_RECEPTOR_SIGNALING_PATHWAY | 74 | 19 | 17377 | 2626 |
PPP3CA,NRAS,AKT2,RAF1,RAC1,VAV2,NFATC2,KRAS,PPP3CB,LYN,MAP2K2,MAPK3,VAV1,NFATC3,PIK3R2,PPP3R1,MAPK1,CD81,HRAS |
| 1.232e-02 | -4.40 | MODULE_243 | MSigDB lists | MODULE_243 | 74 | 19 | 17377 | 2626 |
PGS1,ZBED5,NDUFA4,BCL2L1,HAGH,ECH1,PRDX1,AMZ2,SUB1,PCNA,CCP110,APPL2,PPP6C,ZRANB2,CNOT6,TOB1,MTPN,RTN3,HIGD2A |
| 1.232e-02 | -4.40 | GGCNRNWCTTYS_UNKNOWN | MSigDB lists | GGCNRNWCTTYS_UNKNOWN | 74 | 19 | 17377 | 2626 |
EIF3L,PIGN,KLF10,DDX24,ANKH,SLC39A13,ARFIP2,ADSL,AKT1S1,DNAJA1,SND1,SMAP2,NDUFS4,ZBTB45,RAB8A,FGFR3,C1orf131,TBC1D17,ELMO1 |
| 1.232e-02 | -4.40 | MORF_RFC5 | MSigDB lists | MORF_RFC5 | 74 | 19 | 17377 | 2626 |
MMACHC,PHF10,POLR2K,SIGMAR1,SLC2A1,HABP4,NKRF,UBE4B,BRCA1,CCNF,TAF2,ZNF330,TPP2,ZNF200,TAF12,GLE1,WDR62,PPP5C,CAMK2G |
| 1.232e-02 | -4.40 | MARIADASON_REGULATED_BY_HISTONE_ACETYLATION_UP | MSigDB lists | MARIADASON_REGULATED_BY_HISTONE_ACETYLATION_UP | 74 | 19 | 17377 | 2626 |
PDPK1,UBE2E2,CORO7,MYO9B,BCL2L1,ISG15,MBD4,ADSS,ZNF777,CCP110,FAM110A,INPP5A,SNAP23,ODF2,PPP1R12C,CHMP4B,NCOA1,SLC22A23,ZNF564 |
| 1.232e-02 | -4.40 | chr7q11 | MSigDB lists | chr7q11 | 74 | 19 | 17377 | 2626 |
KCTD7,TYW1,ZNF107,ABHD11,SUMF2,ZP3,RFC2,EIF4H,STYXL1,ZNF92,KRIT1,POLR2J,LIMK1,TPST1,CRCP,BAZ1B,DNAJC30,RHBDD2,TYW1B |
| 1.232e-02 | -4.40 | STUB1 (STIP1 homology and U-box containing protein 1) | protein interactions | 10273 | 269 | 58 | 17029 | 2761 |
MIF,UBE2D3,NADSYN1,UBE2E2,DNAJC5,ATXN3,NQO1,RAF1,XIAP,OLA1,UBE2Q1,DNAJB1,PCBP1,STAM,APP,PARK7,EPM2A,CFLAR,USP5,SRXN1,CDK5,PA2G4,PSMD1,PTEN,RAD23B,JOSD1,PTGES3,AHCYL1,PHKG2,S100A6,TERF2,CDC37,PRPF19,EIF5A,DPM1,VHL,ATXN1,UBE2V1,UBE4B,TOMM40,MEN1,CIP2A,RHBDF2,HSPA1B,EVC2,HSPBP1,SMAD2,HSPA4,GUCY1B1,HIPK2,STK11,MAP3K5,SMAD1,ARRB2,SMURF1,TERF1,POT1,SMAD4 |
| 1.234e-02 | -4.39 | RFC1 (replication factor C subunit 1) | protein interactions | 5981 | 74 | 20 | 17029 | 2761 |
NIFK,RFC3,BRD4,CHTF18,WDR18,RACGAP1,BRCA1,SMC2,BLM,RFC2,RPA1,XRCC5,RPA2,RB1,PCNA,SSBP3,MSH2,CHEK2,MSH6,SMC4 |
| 1.235e-02 | -4.39 | TUBA4A (tubulin alpha 4a) | protein interactions | 7277 | 253 | 55 | 17029 | 2761 |
HSPH1,PRKAB1,CYLD,PRKCSH,MAGED1,RAC1,TKT,MYH9,CUL1,B4GALT1,RACGAP1,CDK13,SIRT2,HAUS2,TUBGCP2,GLMP,RPA2,VAV1,RBM23,PSMD1,SIAH1,ARPC5,UCHL5,YBX1,GNAI2,MLST8,CDC5L,PLK1,STAU1,VHL,NSUN2,CUL3,ILF3,MIER2,BRCA1,IL12RB1,PKM,MCM2,VDAC1,DDX39A,MAP2K2,PSMC4,EPB41,RPA1,CAND1,MAGED2,HLA-B,MBIP,RPS27A,PFDN4,RUVBL2,COPS6,ARRB2,CD81,TUBB |
| 1.235e-02 | -4.39 | LIU_NASOPHARYNGEAL_CARCINOMA | MSigDB lists | LIU_NASOPHARYNGEAL_CARCINOMA | 64 | 17 | 17377 | 2626 |
CDC40,SELPLG,SEC16A,ZNF174,HLA-A,MAT2A,SSR1,DDX17,CD59,RAB8A,DDOST,PITPNA,WIPI2,BTF3,B4GALT3,GM2A,SMARCD1 |
| 1.235e-02 | -4.39 | GO_OLIGOSACCHARIDE_METABOLIC_PROCESS | MSigDB lists | GO_OLIGOSACCHARIDE_METABOLIC_PROCESS | 64 | 17 | 17377 | 2626 |
MAN2A2,PRKCSH,MANBA,MAN1B1,FUT8,CTBS,SLC2A1,HEXB,MOGS,B4GALT1,ST3GAL2,MAN2B1,EDEM2,ST8SIA2,NEU1,GM2A,MAN1A1 |
| 1.235e-02 | -4.39 | GO_ANTIGEN_PROCESSING_AND_PRESENTATION_OF_EXOGENOUS_PEPTIDE_ANTIGEN_VIA_MHC_CLASS_I | MSigDB lists | GO_ANTIGEN_PROCESSING_AND_PRESENTATION_OF_EXOGENOUS_PEPTIDE_ANTIGEN_VIA_MHC_CLASS_I | 64 | 17 | 17377 | 2626 |
PSMA8,HLA-E,PSMB7,PSMA1,ITGB5,PSMB9,PSMD9,PSMB3,HLA-A,PSMC4,PSMD2,HLA-B,PSMA6,PSMD1,PSMD3,PSMD8,PSMC1 |
| 1.236e-02 | -4.39 | GSE12484_HEALTHY_VS_PERIDONTITIS_NEUTROPHILS_DN | MSigDB lists | GSE12484_HEALTHY_VS_PERIDONTITIS_NEUTROPHILS_DN | 137 | 31 | 17377 | 2626 |
WSB2,RPAP3,SLC30A9,CASP6,FAM118B,PPP1R15B,TOR3A,USP42,TRIO,SLC4A2,AGFG1,ATP6V1B2,TXNL4A,NDRG3,CBFB,PCBP1,GFM2,HEATR5B,NCDN,VAV1,CLUAP1,DDOST,NSMCE2,GRSF1,FBXW2,KHSRP,DDX5,ATP6V0D1,MRPL3,GCSH,IPO4 |
| 1.236e-02 | -4.39 | GO_T_CELL_RECEPTOR_SIGNALING_PATHWAY | MSigDB lists | GO_T_CELL_RECEPTOR_SIGNALING_PATHWAY | 137 | 31 | 17377 | 2626 |
PDPK1,LIME1,PSMA8,NCK1,DENND1B,PSMB7,PSMA1,CUL1,BTN3A1,UBE2V1,PSEN1,PSMD9,PSMB9,PSMB3,PSMC4,STOML2,PSMD2,PSMD1,PSMA6,WAS,PTEN,CSK,RPS27A,TAB2,PSMD8,PSMD3,PIK3R2,STK11,MAPK1,PSMC1,HRAS |
| 1.241e-02 | -4.39 | KUWANO_RNA_STABILIZED_BY_NO | MSigDB lists | KUWANO_RNA_STABILIZED_BY_NO | 7 | 4 | 17377 | 2626 |
CHIC2,RGS2,KLF10,GADD45B |
| 1.241e-02 | -4.39 | PETRETTO_BLOOD_PRESSURE_DN | MSigDB lists | PETRETTO_BLOOD_PRESSURE_DN | 7 | 4 | 17377 | 2626 |
FBXL3,XRCC4,RBM8A,CEBPG |
| 1.241e-02 | -4.39 | MARIADASON_RESPONSE_TO_BUTYRATE_CURCUMIN_SULINDAC_TSA_2 | MSigDB lists | MARIADASON_RESPONSE_TO_BUTYRATE_CURCUMIN_SULINDAC_TSA_2 | 7 | 4 | 17377 | 2626 |
UBE2V1,VMP1,MAP1LC3B,NEU1 |
| 1.241e-02 | -4.39 | KUROKAWA_LIVER_CANCER_EARLY_RECURRENCE_DN | MSigDB lists | KUROKAWA_LIVER_CANCER_EARLY_RECURRENCE_DN | 7 | 4 | 17377 | 2626 |
HLA-B,RB1,LCLAT1,HLA-A |
| 1.242e-02 | -4.39 | Golgi reassembly | biological process | GO:0090168 | 4 | 3 | 17256 | 2622 |
VCPIP1,YWHAZ,PDCD10 |
| 1.242e-02 | -4.39 | adenosine 5'-(hexahydrogen pentaphosphate) metabolic process | biological process | GO:1901910 | 4 | 3 | 17256 | 2622 |
NUDT11,NUDT4,NUDT3 |
| 1.242e-02 | -4.39 | negative regulation of nuclear cell cycle DNA replication | biological process | GO:1902576 | 4 | 3 | 17256 | 2622 |
CHEK2,TERF1,TERF2 |
| 1.242e-02 | -4.39 | endoplasmic reticulum tubular network formation | biological process | GO:0071787 | 4 | 3 | 17256 | 2622 |
ZFYVE27,RTN3,ARL6IP1 |
| 1.242e-02 | -4.39 | response to Thyroglobulin triiodothyronine | biological process | GO:1904016 | 4 | 3 | 17256 | 2622 |
NCOA1,NCOA2,SLC2A1 |
| 1.242e-02 | -4.39 | B cell lineage commitment | biological process | GO:0002326 | 4 | 3 | 17256 | 2622 |
BCL2,PRKDC,TCF3 |
| 1.242e-02 | -4.39 | late viral transcription | biological process | GO:0019086 | 4 | 3 | 17256 | 2622 |
USF1,USF2,MON1B |
| 1.242e-02 | -4.39 | adenosine 5'-(hexahydrogen pentaphosphate) catabolic process | biological process | GO:1901911 | 4 | 3 | 17256 | 2622 |
NUDT11,NUDT4,NUDT3 |
| 1.242e-02 | -4.39 | meiotic mismatch repair | biological process | GO:0000710 | 4 | 3 | 17256 | 2622 |
ERCC1,MSH6,MSH2 |
| 1.242e-02 | -4.39 | negative regulation of transcription from RNA polymerase II promoter in response to hypoxia | biological process | GO:0061428 | 4 | 3 | 17256 | 2622 |
SIRT2,CITED2,VHL |
| 1.242e-02 | -4.39 | positive regulation of protein monoubiquitination | biological process | GO:1902527 | 4 | 3 | 17256 | 2622 |
PDCD6,PEF1,BIRC2 |
| 1.242e-02 | -4.39 | regulation of ubiquitin-specific protease activity | biological process | GO:2000152 | 4 | 3 | 17256 | 2622 |
PARK7,UBXN1,TANK |
| 1.242e-02 | -4.39 | neural plate anterior/posterior regionalization | biological process | GO:0021999 | 4 | 3 | 17256 | 2622 |
CELSR2,AXIN1,SSBP3 |
| 1.242e-02 | -4.39 | diadenosine polyphosphate catabolic process | biological process | GO:0015961 | 4 | 3 | 17256 | 2622 |
NUDT11,NUDT4,NUDT3 |
| 1.242e-02 | -4.39 | peptidyl-cysteine oxidation | biological process | GO:0018171 | 4 | 3 | 17256 | 2622 |
PRDX3,PARK7,TMX3 |
| 1.242e-02 | -4.39 | regulation of Golgi inheritance | biological process | GO:0090170 | 4 | 3 | 17256 | 2622 |
MAPK1,MAP2K2,MAPK3 |
| 1.242e-02 | -4.39 | diadenosine pentaphosphate catabolic process | biological process | GO:1901907 | 4 | 3 | 17256 | 2622 |
NUDT11,NUDT4,NUDT3 |
| 1.242e-02 | -4.39 | diphosphoinositol polyphosphate metabolic process | biological process | GO:0071543 | 4 | 3 | 17256 | 2622 |
NUDT11,NUDT4,NUDT3 |
| 1.242e-02 | -4.39 | diadenosine pentaphosphate metabolic process | biological process | GO:1901906 | 4 | 3 | 17256 | 2622 |
NUDT11,NUDT4,NUDT3 |
| 1.242e-02 | -4.39 | positive regulation of amyloid fibril formation | biological process | GO:1905908 | 4 | 3 | 17256 | 2622 |
CLU,PSEN1,APP |
| 1.242e-02 | -4.39 | positive regulation of androgen receptor activity | biological process | GO:2000825 | 4 | 3 | 17256 | 2622 |
RWDD1,PARK7,BUD31 |
| 1.242e-02 | -4.39 | diadenosine hexaphosphate metabolic process | biological process | GO:1901908 | 4 | 3 | 17256 | 2622 |
NUDT11,NUDT4,NUDT3 |
| 1.242e-02 | -4.39 | positive regulation of microtubule nucleation | biological process | GO:0090063 | 4 | 3 | 17256 | 2622 |
MECP2,DCTN1,HSPA1B |
| 1.242e-02 | -4.39 | tRNA dihydrouridine synthesis | biological process | GO:0002943 | 4 | 3 | 17256 | 2622 |
DUS3L,DUS4L,DUS2 |
| 1.242e-02 | -4.39 | PML body organization | biological process | GO:0030578 | 4 | 3 | 17256 | 2622 |
ETS1,HIPK2,PML |
| 1.242e-02 | -4.39 | methylglyoxal metabolic process | biological process | GO:0009438 | 4 | 3 | 17256 | 2622 |
GLO1,HAGH,PARK7 |
| 1.242e-02 | -4.39 | dUMP biosynthetic process | biological process | GO:0006226 | 4 | 3 | 17256 | 2622 |
DCTD,DUT,HDDC2 |
| 1.242e-02 | -4.39 | carbon catabolite activation of transcription from RNA polymerase II promoter | biological process | GO:0000436 | 4 | 3 | 17256 | 2622 |
USF1,NCOA1,USF2 |
| 1.242e-02 | -4.39 | carbon catabolite regulation of transcription from RNA polymerase II promoter | biological process | GO:0000429 | 4 | 3 | 17256 | 2622 |
USF1,NCOA1,USF2 |
| 1.242e-02 | -4.39 | positive regulation of interferon-beta secretion | biological process | GO:0035549 | 4 | 3 | 17256 | 2622 |
DDX58,MAVS,DHX9 |
| 1.242e-02 | -4.39 | diadenosine hexaphosphate catabolic process | biological process | GO:1901909 | 4 | 3 | 17256 | 2622 |
NUDT11,NUDT4,NUDT3 |
| 1.245e-02 | -4.39 | ubiquitin-like protein binding | molecular function | GO:0032182 | 88 | 22 | 17224 | 2647 |
TNFAIP3,RAE1,UBXN1,DCUN1D5,SIRT2,DCUN1D4,TOLLIP,BIRC2,WDR48,NPLOC4,USP5,UBXN2A,PLAA,UBXN2B,FBXO7,NSFL1C,PML,NUP62,TRIM32,CBX4,FAF1,USP13 |
| 1.245e-02 | -4.39 | regulation of cell division | biological process | GO:0051302 | 158 | 35 | 17256 | 2622 |
KIF3B,PKP4,KLHL21,CDK2AP2,CIB1,KIF23,RACGAP1,BCL2L1,SIRT2,BLM,BECN1,RAB11A,CALM2,PDXP,AHCTF1,CCP110,CDC42,PIN1,KIF14,PRC1,YBX1,CDC25B,TGFB1,PLK3,PLK1,RHOA,ASPM,CUL3,CDC6,AURKB,SH3GLB1,CAT,KIF18B,NUP62,VPS4A |
| 1.248e-02 | -4.38 | GNAT | prosite domains | PS51186 | 24 | 8 | 12060 | 1670 |
NAT14,NAT9,GNPNAT1,NAA20,KAT2A,SAT2,NAA60,NAA50 |
| 1.249e-02 | -4.38 | GSE339_CD4POS_VS_CD4CD8DN_DC_UP | MSigDB lists | GSE339_CD4POS_VS_CD4CD8DN_DC_UP | 192 | 41 | 17377 | 2626 |
WASF2,AGRN,UFC1,LAGE3,PCSK7,SLC29A1,MXD4,ARF1,MAPK14,METTL3,APP,PIP4K2A,HDDC2,SPAG5,FBRS,EEF2K,LHX8,PHTF1,ARL6IP1,ATG13,LPCAT1,PCBP2,PDCL3,TERF2,ADCY7,ACP2,TRAFD1,ATP6V1D,PDRG1,STK38,WNT5B,MRPL27,STAT1,CANT1,SSNA1,CD81,MYL12B,NAA60,VPS29,NUDT3,ADAM23 |
| 1.249e-02 | -4.38 | GSE15930_STIM_VS_STIM_AND_IL-12_48H_CD8_T_CELL_UP | MSigDB lists | GSE15930_STIM_VS_STIM_AND_IL-12_48H_CD8_T_CELL_UP | 192 | 41 | 17377 | 2626 |
GOLPH3L,BABAM1,TAP1,SLC4A2,SLC29A1,MAN2B1,POMP,USP48,MAP1LC3B,LCLAT1,LYRM2,GNB2,PHC2,GOLM1,CTSS,TIMELESS,CDKN1B,TAP2,MAST2,GLE1,RNF26,FRMD8,CTDSP2,PABPC1,HNRNPM,PPP1R18,NEK7,ITM2A,ESYT1,ICAM2,ARPC1A,CHCHD6,RBM38,HHEX,PEX5,PDRG1,CSK,FAM3C,CLN3,LTA4H,NRBP1 |
| 1.249e-02 | -4.38 | GSE39152_CD103_NEG_VS_POS_MEMORY_CD8_TCELL_DN | MSigDB lists | GSE39152_CD103_NEG_VS_POS_MEMORY_CD8_TCELL_DN | 192 | 41 | 17377 | 2626 |
SLC12A7,SCAMP3,MDH2,GADD45G,SLC2A1,UCK2,ALKBH5,ARFIP2,BCL2L1,SLC35B1,AP1B1,EIF1B,PAPOLA,FARSA,IARS,RRBP1,MRPL34,ARHGEF2,TIPARP,STAT3,UBE2M,PPA1,ABCC1,SAMD4B,RHOA,POLK,CIC,ABCF2,SSR2,KRTCAP2,BSDC1,CAND1,STOML2,GALNT2,KPNA1,PSMD3,NFIL3,MZT2B,ABCA1,HIPK3,RAB3IL1 |
| 1.249e-02 | -4.38 | GSE360_HIGH_DOSE_B_MALAYI_VS_M_TUBERCULOSIS_MAC_UP | MSigDB lists | GSE360_HIGH_DOSE_B_MALAYI_VS_M_TUBERCULOSIS_MAC_UP | 192 | 41 | 17377 | 2626 |
NUP188,TMEM184B,KIAA0100,UBN1,DAP,ADO,SND1,ITGB5,USP5,SF3B2,VAV1,FARSA,SIAH1,BANF1,TXLNA,AKR1B1,CDC25B,CYB5R1,FBL,EEF1D,ABCC5,MAPRE2,SEC61B,TSTA3,ERF,KIAA0930,ATP6V0A1,DIDO1,NUTF2,COMMD4,NEU1,NMT2,IRF5,MFN2,PI4K2A,TPD52L2,DUSP3,COPS6,CLN3,HEXA,LTA4H |
| 1.254e-02 | -4.38 | EXOSC2 (exosome component 2) | protein interactions | 23404 | 60 | 17 | 17029 | 2761 |
EXOSC6,DHPS,PRRC2A,EXOSC9,ORC1,METTL22,ASXL2,COMMD4,CAND1,EXOSC7,UPF1,EXOSC1,PRC1,KHSRP,UPF2,MRPL48,IFI16 |
| 1.254e-02 | -4.38 | NEURL4 (neuralized E3 ubiquitin protein ligase 4) | protein interactions | 84461 | 60 | 17 | 17029 | 2761 |
GALC,MAP7D1,RAB5B,KTN1,SPAG5,POLR2A,RPA1,RPA2,SMC3,PCM1,CCP110,ODF2,MAPK6,USP20,GPI,PSMC1,SSSCA1 |
| 1.254e-02 | -4.38 | SLC7A1 (solute carrier family 7 member 1) | protein interactions | 6541 | 60 | 17 | 17029 | 2761 |
NAT14,ELOVL5,NDC1,ACP2,GPR89A,AGPAT3,SLC35B2,APP,LMNA,GOLM1,LEMD2,TMEM268,TIMM29,PARL,CYB5R1,MAVS,MGAT5 |
| 1.254e-02 | -4.38 | HMOX2 (heme oxygenase 2) | protein interactions | 3163 | 60 | 17 | 17029 | 2761 |
IMMT,TMEM216,CSNK2A1,NKRF,ADPGK,ATP5F1B,DUSP22,APP,GNB2,LMNA,EVC2,ABHD5,SHC1,ZNF746,CISD2,RBBP4,COPS6 |
| 1.254e-02 | -4.38 | CTSD (cathepsin D) | protein interactions | 1509 | 60 | 17 | 17029 | 2761 |
MLEC,PPT1,LDHA,PCBP1,RAB5B,SCYL2,APP,HUWE1,UCHL5,PPME1,H2AFX,SUCLG2,CTSA,PSAP,ACADM,MAPK1,LDHB |
| 1.256e-02 | -4.38 | V$MYCMAX_01 | MSigDB lists | V$MYCMAX_01 | 237 | 49 | 17377 | 2626 |
POU3F2,ZBTB10,NDUFS1,EWSR1,IVNS1ABP,GADD45G,MXD4,ZADH2,STMN1,FOXO3,KCMF1,TFRC,CSDE1,LYAR,TFAP4,PA2G4,SMC3,CD3EAP,SUCLG2,MRPL40,PABPC1,NUDC,USP34,SRP72,AMPD2,PPP1R9B,NRAS,SIGMAR1,LAP3,SUGP2,ILF3,KRTCAP2,KDM3A,ODC1,MAT2A,EPB41,SMAD2,SYNCRIP,CSK,HNRNPH3,DCAF11,BCL7C,TCOF1,CLN3,ABCA1,LRP8,GCSH,RAB3IL1,RHEBL1 |
| 1.258e-02 | -4.38 | CCTGAGT,MIR-510 | MSigDB lists | CCTGAGT,MIR-510 | 40 | 12 | 17377 | 2626 |
RORB,PRKAB1,SERF2,TRIP12,FAM53C,OAZ2,RBM3,IP6K2,CAPZA2,ST8SIA2,CAMK2G,FANCI |
| 1.258e-02 | -4.38 | GO_POSITIVE_REGULATION_OF_ATPASE_ACTIVITY | MSigDB lists | GO_POSITIVE_REGULATION_OF_ATPASE_ACTIVITY | 40 | 12 | 17377 | 2626 |
DNAJC10,DNAJC2,AHSA1,TOR1AIP1,RAB4A,DNM2,DNAJC24,DNAJC9,TOR1AIP2,ADRB2,DNAJB1,CHTOP |
| 1.258e-02 | -4.38 | JIANG_AGING_HYPOTHALAMUS_DN | MSigDB lists | JIANG_AGING_HYPOTHALAMUS_DN | 40 | 12 | 17377 | 2626 |
KIF5B,PLD3,EPRS,RAB18,ATP2A2,MAGED1,CS,ATP6V0C,GNAI2,DDB1,CAMK2G,GPX4 |
| 1.258e-02 | -4.38 | GO_NEGATIVE_REGULATION_OF_STRESS_ACTIVATED_PROTEIN_KINASE_SIGNALING_CASCADE | MSigDB lists | GO_NEGATIVE_REGULATION_OF_STRESS_ACTIVATED_PROTEIN_KINASE_SIGNALING_CASCADE | 40 | 12 | 17377 | 2626 |
HSPH1,FOXM1,DUSP3,GPS2,PBK,ZMYND11,EZR,DNAJA1,MEN1,IGBP1,HIPK3,PDCD4 |
| 1.258e-02 | -4.38 | GO_NEGATIVE_REGULATION_OF_STRESS_ACTIVATED_MAPK_CASCADE | MSigDB lists | GO_NEGATIVE_REGULATION_OF_STRESS_ACTIVATED_MAPK_CASCADE | 40 | 12 | 17377 | 2626 |
HSPH1,FOXM1,DUSP3,GPS2,PBK,ZMYND11,EZR,DNAJA1,MEN1,IGBP1,HIPK3,PDCD4 |
| 1.258e-02 | -4.38 | KAAB_FAILED_HEART_VENTRICLE_DN | MSigDB lists | KAAB_FAILED_HEART_VENTRICLE_DN | 40 | 12 | 17377 | 2626 |
ATP2A2,NQO2,AMD1,LPCAT4,PQBP1,LDHA,GTF3A,TMEM147,STAT3,PTDSS1,ISG15,EBP |
| 1.258e-02 | -4.38 | PID_EPHB_FWD_PATHWAY | MSigDB lists | PID_EPHB_FWD_PATHWAY | 40 | 12 | 17377 | 2626 |
RAP1A,NRAS,SHC1,CDC42,NCK1,MAP4K4,RAC1,KRAS,ROCK1,MAPK1,HRAS,MAPK3 |
| 1.258e-02 | -4.38 | GO_INTERCELLULAR_BRIDGE | MSigDB lists | GO_INTERCELLULAR_BRIDGE | 40 | 12 | 17377 | 2626 |
SNRNP25,DNAJC8,THOC1,RAB35,LYRM1,CEP55,XPA,RFXANK,CDCA8,KIF23,AURKB,KRR1 |
| 1.258e-02 | -4.38 | RNA polymerase II transcription coactivator activity | molecular function | GO:0001105 | 44 | 13 | 17224 | 2647 |
POU3F2,POU2AF1,HIPK2,DHX9,WBP2,SMARCA4,MEF2A,BRCA1,NCOA1,CITED2,SOX4,TRIM28,CARM1 |
| 1.260e-02 | -4.37 | GSE22611_UNSTIM_VS_6H_MDP_STIM_NOD2_TRANSDUCED_HEK293T_CELL_DN | MSigDB lists | GSE22611_UNSTIM_VS_6H_MDP_STIM_NOD2_TRANSDUCED_HEK293T_CELL_DN | 181 | 39 | 17377 | 2626 |
CMAS,NSMCE4A,TRIP10,GNPDA1,UROD,TRIO,DLGAP4,ZNF107,EZH1,USP48,DCUN1D4,PRKACA,LRRC14,MEX3C,GATC,HDAC7,RABGAP1L,UBA5,ATP13A3,MRPL40,UBE3B,MRPL11,EIF5,PLCL2,EIF5A,PHF10,ADAM17,TIMP2,RPS24,RANGAP1,RTF1,RAB1A,MBD3,MTR,SH3BP5,PLAA,TTLL4,APPL2,IDH3B |
| 1.260e-02 | -4.37 | GSE43955_1H_VS_10H_ACT_CD4_TCELL_WITH_TGFB_IL6_UP | MSigDB lists | GSE43955_1H_VS_10H_ACT_CD4_TCELL_WITH_TGFB_IL6_UP | 181 | 39 | 17377 | 2626 |
RMND5A,PRKAB1,PHB2,CAST,WDTC1,BRAP,GYG1,FKBP2,CDK11B,AP3S1,CSDE1,GOLM1,NDUFB4,NUP107,CS,CRY2,PCBP2,SAP30,CLCN3,HMGN5,NET1,RAD51AP1,MFNG,HTATIP2,EIF2AK1,NUSAP1,UTP3,IL12RB1,RPSA,DNAJC10,PLAA,RAB24,FASTK,COX7A2L,BCL7C,CD81,UBE2C,HEXA,USF2 |
| 1.260e-02 | -4.37 | GSE40068_BCL6_POS_VS_NEG_CXCR5_POS_TFH_UP | MSigDB lists | GSE40068_BCL6_POS_VS_NEG_CXCR5_POS_TFH_UP | 181 | 39 | 17377 | 2626 |
PDCD6IP,LIME1,TMEM184B,FAM129A,TPX2,PXMP2,POMP,SSR1,DTL,FLAD1,IRF4,ATP2A2,SRI,PRC1,MRPL34,GTSE1,AHCY,CCAR1,MND1,SEC61B,NEK7,RAD51AP1,LDHA,NFATC2,CCNF,SHCBP1,BORA,ARPC1A,ASF1B,RDH11,OPTN,UBXN2B,NFIL3,EXOC4,PML,ATF6,UBE2C,NGLY1,POLQ |
| 1.260e-02 | -4.37 | GSE25088_ROSIGLITAZONE_VS_IL4_AND_ROSIGLITAZONE_STIM_MACROPHAGE_DAY10_UP | MSigDB lists | GSE25088_ROSIGLITAZONE_VS_IL4_AND_ROSIGLITAZONE_STIM_MACROPHAGE_DAY10_UP | 181 | 39 | 17377 | 2626 |
SYS1,AGTRAP,PHRF1,MANBA,EIF3D,VAV2,TMX4,HMGN3,FKBP2,RCOR3,FOXO3,CEP104,KLHL20,UBA5,PHTF1,ZNF335,BRD7,PIK3IP1,TOP1MT,LDLRAD3,C12orf75,MTPN,LDHB,PRKDC,NLN,CYFIP2,MEN1,SOCS7,PON2,PEX5,SCAP,DTX4,COX8A,FAM122A,ROCK1,PPP6R3,RNF14,LRP8,PDCD4 |
| 1.262e-02 | -4.37 | response to nitric oxide | biological process | GO:0071731 | 18 | 7 | 17256 | 2622 |
CCNA2,CDK2,GUCY1B1,MTR,CFLAR,EGLN1,DNM2 |
| 1.262e-02 | -4.37 | magnesium ion transport | biological process | GO:0015693 | 18 | 7 | 17256 | 2622 |
NIPAL3,NIPA2,MAGT1,SLC41A1,NIPA1,MRS2,ZDHHC13 |
| 1.262e-02 | -4.37 | kinetochore organization | biological process | GO:0051383 | 18 | 7 | 17256 | 2622 |
NUF2,SMC2,CENPT,CDT1,CENPF,MIS12,SMC4 |
| 1.262e-02 | -4.37 | COPS9 (COP9 signalosome subunit 9) | protein interactions | 150678 | 17 | 7 | 17029 | 2761 |
CUL1,COPS8,UNK,COPS6,RPL11,C19orf25,CUL3 |
| 1.262e-02 | -4.37 | KCTD15 (potassium channel tetramerization domain containing 15) | protein interactions | 79047 | 17 | 7 | 17029 | 2761 |
ATXN1,RUVBL2,PRPF39,NSMF,TERF1,TERF2,ENSA |
| 1.262e-02 | -4.37 | TRIM47 (tripartite motif containing 47) | protein interactions | 91107 | 17 | 7 | 17029 | 2761 |
CUL1,TNS3,TRIM8,PPP1R12A,APP,TPP2,TERF2 |
| 1.262e-02 | -4.37 | UQCR10 (ubiquinol-cytochrome c reductase, complex III subunit X) | protein interactions | 29796 | 17 | 7 | 17029 | 2761 |
KRAS,CYC1,TIMMDC1,RAB11A,NDUFA11,HNRNPM,CYSTM1 |
| 1.262e-02 | -4.37 | SPAG8 (sperm associated antigen 8) | protein interactions | 26206 | 17 | 7 | 17029 | 2761 |
JMJD4,KDM3B,NSD3,UBQLN4,PRMT2,PITX1,CARM1 |
| 1.262e-02 | -4.37 | Cdkn2aip (CDKN2A interacting protein) | protein interactions | 70925 | 17 | 7 | 17029 | 2761 |
TFAP4,NANP,MRPL55,ARID2,GPATCH4,TERF2,RRM1 |
| 1.262e-02 | -4.37 | ETFRF1 (electron transfer flavoprotein regulatory factor 1) | protein interactions | 144363 | 17 | 7 | 17029 | 2761 |
NADK2,CHCHD2,NDUFB9,CYCS,CCZ1,ECH1,RCC1L |
| 1.262e-02 | -4.37 | ZNF704 (zinc finger protein 704) | protein interactions | 619279 | 17 | 7 | 17029 | 2761 |
SAP130,CUL1,BRMS1,IMPDH1,SAP30L,ARID4A,SAP30 |
| 1.262e-02 | -4.37 | CACNG4 (calcium voltage-gated channel auxiliary subunit gamma 4) | protein interactions | 27092 | 17 | 7 | 17029 | 2761 |
YIF1A,ANAPC7,MTX1,MTX3,TMEM126B,CSNK1D,MRS2 |
| 1.262e-02 | -4.37 | SPHK1 (sphingosine kinase 1) | protein interactions | 8877 | 17 | 7 | 17029 | 2761 |
CYLD,BIRC3,DHPS,BECN1,RPS6KC1,LYN,PPM1G |
| 1.265e-02 | -4.37 | CUI_TCF21_TARGETS_2_DN | MSigDB lists | CUI_TCF21_TARGETS_2_DN | 770 | 139 | 17377 | 2626 |
AGFG1,GYG1,PPP1R16B,RNF103,DST,RAP1A,DPYSL2,RABGAP1L,IL6ST,TIPARP,MGAT5,ARID4A,MBLAC2,LRBA,MCL1,SLC17A5,OPTN,KRIT1,HHEX,AHNAK,MYO18A,ITGB1,ADAM9,ROCK1,GALNT10,GLCCI1,CHPT1,FAM208A,DCAF5,NXT2,WSB2,TBC1D12,PARP12,SCOC,PPP1R2,C16orf87,PRKAA1,SDC2,RGS2,ZNF518A,ITGB5,CDC73,CFLAR,ATG4A,UBE2Q2,KLHL5,ZNRF2,RNFT1,FOXN2,SLC12A2,CSNK1G3,LUC7L2,IFRD1,ELL2,ICAM2,ARMC8,NSF,DUSP3,SNAP23,NFIL3,PTAR1,SAMD8,EHD4,C11orf1,TOB1,CABLES1,ZC3HAV1,ASH1L,UGP2,CAST,KIAA1147,RALB,LPIN2,CORO1A,TOP1MT,TMBIM1,EBAG9,ENPP4,ARHGAP17,PGGT1B,ANKRD33B,GOPC,COQ10B,TAOK1,CYP20A1,MTMR6,PFKFB3,TOR1AIP2,BICD2,TANC1,AP4E1,PON2,JAK1,CERS6,STAT1,RBMS1,H3F3A,TSPAN5,DYNC1LI2,TMEM33,LRCH1,SRGN,FAM76A,CHAC2,ETS1,HEATR5B,MAN1A1,TMCC3,KIF5B,FBXO3,HOMER1,CTSS,ITGB8,CITED2,PDLIM2,PHF20L1,FAM49B,TNFAIP3,TACC1,GALC,BTAF1,USP42,PARP4,MACF1,HAGH,SH3GLB1,ZFR,HSPA1B,SH3BP5,INF2,NEK1,ZHX1,OSBPL8,ACOX1,CTBS,BBX,CPEB2,HIPK3,PURA |
| 1.266e-02 | -4.37 | modulation of age-related behavioral decline | biological process | GO:0090647 | 7 | 4 | 17256 | 2622 |
PSEN1,APP,PICALM,PRNP |
| 1.266e-02 | -4.37 | transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery | biological process | GO:0000972 | 7 | 4 | 17256 | 2622 |
NUP155,RAE1,LDB1,NUP107 |
| 1.266e-02 | -4.37 | posttranslational protein targeting to endoplasmic reticulum membrane | biological process | GO:0006620 | 7 | 4 | 17256 | 2622 |
CHMP4B,SEC61B,CHMP4A,SEC61A1 |
| 1.266e-02 | -4.37 | hair follicle maturation | biological process | GO:0048820 | 7 | 4 | 17256 | 2622 |
RBPJ,NF1,MYO5A,NSUN2 |
| 1.266e-02 | -4.37 | plus-end-directed vesicle transport along microtubule | biological process | GO:0072383 | 7 | 4 | 17256 | 2622 |
KIF5B,KIF23,KIFAP3,KIF3B |
| 1.266e-02 | -4.37 | protein localization to cytoplasmic stress granule | biological process | GO:1903608 | 7 | 4 | 17256 | 2622 |
DCP1A,TIA1,YBX1,DHX9 |
| 1.266e-02 | -4.37 | negative regulation of protein polyubiquitination | biological process | GO:1902915 | 7 | 4 | 17256 | 2622 |
TRIP12,PLAA,GPS2,PARP10 |
| 1.266e-02 | -4.37 | strand invasion | biological process | GO:0042148 | 7 | 4 | 17256 | 2622 |
XRCC3,RAD51C,RAD51D,XRCC2 |
| 1.266e-02 | -4.37 | GSE46606_UNSTIM_VS_CD40L_IL2_IL5_3DAY_STIMULATED_IRF4_KO_BCELL_DN | MSigDB lists | GSE46606_UNSTIM_VS_CD40L_IL2_IL5_3DAY_STIMULATED_IRF4_KO_BCELL_DN | 170 | 37 | 17377 | 2626 |
PWWP2A,DDX58,MMACHC,UBE2E2,ZNF496,PARP12,MTX3,MYO9B,ERH,KLF16,INTS7,DNAAF2,ZCCHC2,FEM1B,TRA2B,INTS12,YBX1,PRADC1,METTL1,RPAP3,CYFIP1,MKLN1,PGGT1B,POLK,ZNF202,TOP3A,SMU1,ILF3,TBRG4,AMDHD2,BORA,TAF2,HLA-B,TRIM47,C1orf109,ZNF268,RGL1 |
| 1.266e-02 | -4.37 | GSE37301_PRO_BCELL_VS_RAG2_KO_NK_CELL_UP | MSigDB lists | GSE37301_PRO_BCELL_VS_RAG2_KO_NK_CELL_UP | 170 | 37 | 17377 | 2626 |
IER2,PIGM,LZTR1,CASP6,RPS6KA1,PLXNA1,FKBP2,CDIPT,AP3S1,CMTM6,LMNA,EEF2K,CAPN2,ATP6V0B,SEPT11,GM2A,ALDH9A1,ERMP1,RHOA,RAB7A,ATP6V0A1,EZR,PLEC,IL12RB1,MAP2K2,MID1IP1,DHX16,TATDN2,ACLY,ACBD4,ATF6,NDUFS5,ARHGAP23,LONP2,LRP8,FAF1,NXT2 |
| 1.266e-02 | -4.37 | GSE10856_CTRL_VS_TNFRSF6B_IN_MACROPHAGE_UP | MSigDB lists | GSE10856_CTRL_VS_TNFRSF6B_IN_MACROPHAGE_UP | 170 | 37 | 17377 | 2626 |
SEPHS2,SMAP1,RPLP2,UBXN1,PMF1,AP1B1,COMMD5,DAZAP2,CALM2,KDM2A,TNFAIP8,DAPK1,BRI3,PIK3IP1,GNAI2,CNPY3,LPCAT1,ABCC5,ORAI2,KAT7,SLBP,NLN,FAM50B,PLEC,ZFAND5,SMAP2,NEU1,TRIM4,KIF18A,PEX5,DUSP3,NRM,APPL2,CTSA,PSAP,DEF6,ZSWIM6 |
| 1.266e-02 | -4.37 | negative regulation of biosynthetic process | biological process | GO:0009890 | 1584 | 272 | 17256 | 2622 |
TXN,ZNF496,MAX,H2AFZ,KDM4A,TSC22D3,YTHDF3,UBE2I,RBM4,PARK7,CDK5,PA2G4,CIPC,CRY2,FNIP2,SMARCE1,DNMT1,PLK3,KLF10,AATF,GABPA,EHMT1,DDX20,AURKB,DOT1L,BRMS1,HHEX,SMAD2,RPS27A,RPS14,AXIN1,PRDX5,TFDP2,HDAC2,PDCD4,PRKAA1,EIF2AK4,PSEN1,METTL3,CDC73,CNOT3,CFLAR,TFAP4,SMC3,MEX3C,KLF16,HDAC7,PHF14,DAPK1,GNAI2,LPCAT1,TNRC18,TERF2,ETV3,FOXK1,ZMYND11,MTA2,GTPBP4,ITM2A,BCLAF1,ARID1A,CBFA2T2,FXR1,PHF6,XRCC5,EPRS,PFDN5,ETS2,QARS,YY1,ZNF830,CDK2,RNF139,CDKN2A,EGLN1,ZNF296,DNMT3A,SUZ12,UBR2,MAGED1,WDTC1,RCOR3,PAIP2,SPINDOC,SHC1,SP100,MTA1,CDKN1B,RBM15,ATF2,CGGBP1,SAP30,ERF,EID1,DRAP1,CIRBP,CUL3,H2AFV,TRIM28,CHCHD3,ZNF282,HIPK2,H2AFX,STAT1,BEND3,LRP8,NCOR2,DEPDC1,MECP2,TCF3,BLM,HMG20A,FOXO3,MAD2L2,WWP2,SUV39H2,CITED2,CNOT6L,CREB1,NCOA2,TSHZ1,ILF3,ZP3,CBX3,GPS2,ZHX1,PITX1,PML,KHSRP,HMGB2,DDX5,IGBP1,CPEB2,PURA,RORB,TRIM11,SIRT2,CREM,RAP1A,GLIS2,EIF4A3,JAZF1,METTL14,ZNF639,ETV6,NOC2L,ARID4A,CCAR1,PTPRK,RYBP,SP3,PLK1,DEAF1,BAZ2A,NCK1,PBXIP1,VHL,RIOX2,EZR,CDC6,BRCA1,PAF1,EIF4ENIF1,TONSL,ZNF268,STK11,CHEK2,BEND6,POT1,ZNF564,UBE2D3,PHB2,CENPF,TIA1,CTCF,MEF2A,DNAJB1,TTF1,LYAR,RB1,NFATC3,MLX,TIGAR,MBD2,ZNF746,TIMELESS,CTR9,YBX1,MDFIC,MCPH1,ZNF189,CREG1,CIC,ERLIN1,LDB1,RTF1,EIF2AK1,ZNF174,DAPK3,TSC1,SYNCRIP,ORMDL2,NFIL3,SIAH2,ZFP90,RUVBL2,TOB1,N4BP2L2,MBD1,MPHOSPH8,FOXM1,SMARCA4,IRF3,DUSP22,MXD1,HNRNPA2B1,SAP130,ZBTB21,MDM2,STRAP,MOSPD1,RLIM,FAM172A,PGGT1B,ZNF500,BTG2,PCGF6,ATXN1,NFATC2,MBD3,ATP1A1,SCAP,HNRNPR,RBL1,STAT6,MAFK,ARNTL,DNAJC17,H3F3A,SMAD4,CBX4,DNAJC2,UNK,DAP,AGO2,ARID5A,NKRF,PAWR,MXD4,PTPN2,KMT5A,BRD7,H2AFY,STAT3,RBM15B,SAMD4B,TGFB1,RHOA,ZNF202,PSPC1,BTAF1,RCOR1,MEN1,PRMT2,CNOT9,UPF1,BIRC5,E2F1,RBPJ,NR2F2,TERF1,IFI16 |
| 1.269e-02 | -4.37 | LSM12 (LSM12 homolog) | protein interactions | 124801 | 29 | 10 | 17029 | 2761 |
GOLM1,HPDL,HUWE1,ATXN2L,CUL3,TARDBP,FUS,PCBP1,IFI16,CAND1 |
| 1.269e-02 | -4.37 | CCDC12 (coiled-coil domain containing 12) | protein interactions | 151903 | 29 | 10 | 17029 | 2761 |
CDC40,PPIE,BUD31,CRNKL1,YJU2,DHX8,SNRPG,VKORC1,LUC7L2,PRPF19 |
| 1.269e-02 | -4.37 | GTPBP1 (GTP binding protein 1) | protein interactions | 9567 | 29 | 10 | 17029 | 2761 |
VASP,MEX3C,CORO1C,PRC1,CUL3,SNRNP70,APP,IRF5,CDC5L,CAND1 |
| 1.269e-02 | -4.37 | HIST1H2BJ (histone cluster 1 H2B family member j) | protein interactions | 8970 | 29 | 10 | 17029 | 2761 |
MDM2,MCM5,E2F4,STAT1,E2F1,JMJD6,USP48,CREB1,MCM2,CD81 |
| 1.269e-02 | -4.37 | ZNF668 (zinc finger protein 668) | protein interactions | 79759 | 29 | 10 | 17029 | 2761 |
NOL12,MDM2,DGCR8,ZNF512,RPL8,KIF22,KIF2C,MATR3,RBM4,GPATCH4 |
| 1.269e-02 | -4.37 | DSC1 (desmocollin 1) | protein interactions | 1823 | 29 | 10 | 17029 | 2761 |
PLK1,PRKAB1,CYLD,UCHL5,MCM5,UBXN1,TARDBP,MCM2,GOSR1,CDK2 |
| 1.269e-02 | -4.37 | KPNA5 (karyopherin subunit alpha 5) | protein interactions | 3841 | 29 | 10 | 17029 | 2761 |
PTPN2,BRMS1,PHB2,CUL3,ANP32A,CDKN1B,ZRANB2,MCM2,RBBP4,FBL |
| 1.269e-02 | -4.37 | Ckap5 (cytoskeleton associated protein 5) | protein interactions | 75786 | 29 | 10 | 17029 | 2761 |
TRIM47,IMMT,ERLIN1,TUFM,ACADM,ATP5F1A,GCC1,ERC1,TACC3,CCDC127 |
| 1.269e-02 | -4.37 | MTMR3 (myotubularin related protein 3) | protein interactions | 8897 | 29 | 10 | 17029 | 2761 |
ANKRD28,MTMR3,PLK1,DNAJC10,MTMR4,TULP3,CUL3,PNO1,NUP205,MLST8 |
| 1.269e-02 | -4.37 | GOLGA4 (golgin A4) | protein interactions | 2803 | 29 | 10 | 17029 | 2761 |
GEMIN5,NOL11,ATP5MC3,VHL,TKT,RAB6A,MACF1,APP,UTP4,ZER1 |
| 1.269e-02 | -4.37 | TMEM199 (transmembrane protein 199) | protein interactions | 147007 | 29 | 10 | 17029 | 2761 |
ERLIN1,TMEM216,ATP6V0A1,ATP6V0A2,ATP6V0C,ECPAS,ATP6V0E1,ATP6V0D1,LMNA,EVC2 |
| 1.269e-02 | -4.37 | HMGB3 (high mobility group box 3) | protein interactions | 3149 | 29 | 10 | 17029 | 2761 |
TERF2IP,TFAP4,EWSR1,UBXN1,YWHAH,SDHA,SUPT16H,MCTS1,CAND1,SSRP1 |
| 1.269e-02 | -4.37 | KRI1 (KRI1 homolog) | protein interactions | 65095 | 29 | 10 | 17029 | 2761 |
ANKRD28,NOL12,RPS2,AATF,RPS14,RPL6,ZC3H3,IFI16,RPSA,SUPT16H |
| 1.272e-02 | -4.36 | Gemcitabine Action Pathway | SMPDB pathways | SMP00446 | 13 | 6 | 992 | 167 |
RRM2,DCTD,SLC29A1,DCK,CTPS1,RRM1 |
| 1.272e-02 | -4.36 | Gemcitabine Metabolism Pathway | SMPDB pathways | SMP00603 | 13 | 6 | 992 | 167 |
RRM2,DCTD,SLC29A1,DCK,CTPS1,RRM1 |
| 1.273e-02 | -4.36 | PID_CXCR4_PATHWAY | MSigDB lists | PID_CXCR4_PATHWAY | 100 | 24 | 17377 | 2626 |
PDPK1,RHOA,RHOC,RAC1,LYN,RHOB,RGS1,VAV1,HGS,CDC42,PTEN,RALB,CSK,LIMK1,PIK3R2,STAT1,ITGB1,PTPN11,VPS4A,GNAI2,ARRB2,STAT3,CFL1,MLST8 |
| 1.274e-02 | -4.36 | MARTORIATI_MDM4_TARGETS_FETAL_LIVER_UP | MSigDB lists | MARTORIATI_MDM4_TARGETS_FETAL_LIVER_UP | 209 | 44 | 17377 | 2626 |
CCNC,GALK1,TAP1,LAGE3,PTP4A3,GLRX3,FOXO3,APOPT1,TFAP4,RB1,USF1,PDXP,MDM2,CCP110,SYNM,DUS4L,SIVA1,DAPK1,EI24,NDUFB9,PIK3IP1,RNF19A,LUC7L2,RNF169,SAP30,TIMM8B,CLCN3,PSRC1,ANKRD37,MAPKAPK3,BTG2,LLPH,NDUFA7,RHBDF2,HSPBP1,EXOC4,AEN,SNRPG,NAA20,CD81,ZMAT3,DEF6,PFKP,EGLN1 |
| 1.280e-02 | -4.36 | peptidyl-lysine acetylation | biological process | GO:0018394 | 110 | 26 | 17256 | 2622 |
KAT2A,KAT7,MECP2,LDB1,ELP4,TAF6L,USP22,WDR5,SUPT7L,MBD3,MEAF6,IRF4,MBIP,BRPF3,TEX30,OGT,NAA50,KANSL2,TAF5L,RUVBL2,NCOA1,BEND3,TAF12,ATF2,NAA60,SGF29 |
| 1.280e-02 | -4.36 | human chr16p11.2 | chromosome location | human chr16p11.2 | 139 | 24 | 26185 | 2809 |
SEPHS2,ZNF768,TUFM,NFATC2IP,ZNF267,INO80E,VKORC1,CDIPT,PAGR1,MAPK3,FBRS,SEPT1,ZNF689,ATXN2L,BCL7C,TMEM219,KIF22,CORO1A,FUS,MVP,FBXL19,SGF29,PHKG2,ZNF720 |
| 1.283e-02 | -4.36 | inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity | molecular function | GO:0052844 | 4 | 3 | 17224 | 2647 |
NUDT11,NUDT4,NUDT3 |
| 1.283e-02 | -4.36 | thiol oxidase activity | molecular function | GO:0016972 | 4 | 3 | 17224 | 2647 |
GFER,QSOX2,TMX3 |
| 1.283e-02 | -4.36 | tRNA dihydrouridine synthase activity | molecular function | GO:0017150 | 4 | 3 | 17224 | 2647 |
DUS4L,DUS3L,DUS2 |
| 1.283e-02 | -4.36 | histone pre-mRNA DCP binding | molecular function | GO:0071208 | 4 | 3 | 17224 | 2647 |
SLBP,SNRPD3,SNRPB |
| 1.283e-02 | -4.36 | inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity | molecular function | GO:0052845 | 4 | 3 | 17224 | 2647 |
NUDT11,NUDT4,NUDT3 |
| 1.283e-02 | -4.36 | single base insertion or deletion binding | molecular function | GO:0032138 | 4 | 3 | 17224 | 2647 |
MSH6,PMS2,MSH2 |
| 1.283e-02 | -4.36 | angiostatin binding | molecular function | GO:0043532 | 4 | 3 | 17224 | 2647 |
ATP5IF1,ATP5F1A,ATP5F1B |
| 1.283e-02 | -4.36 | diphosphoinositol-polyphosphate diphosphatase activity | molecular function | GO:0008486 | 4 | 3 | 17224 | 2647 |
NUDT11,NUDT4,NUDT3 |
| 1.283e-02 | -4.36 | inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity | molecular function | GO:0052846 | 4 | 3 | 17224 | 2647 |
NUDT11,NUDT4,NUDT3 |
| 1.283e-02 | -4.36 | inositol diphosphate tetrakisphosphate diphosphatase activity | molecular function | GO:0052840 | 4 | 3 | 17224 | 2647 |
NUDT11,NUDT4,NUDT3 |
| 1.283e-02 | -4.36 | bis(5'-adenosyl)-pentaphosphatase activity | molecular function | GO:0034432 | 4 | 3 | 17224 | 2647 |
NUDT11,NUDT4,NUDT3 |
| 1.283e-02 | -4.36 | inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity | molecular function | GO:0052847 | 4 | 3 | 17224 | 2647 |
NUDT11,NUDT4,NUDT3 |
| 1.283e-02 | -4.36 | inositol diphosphate pentakisphosphate diphosphatase activity | molecular function | GO:0052842 | 4 | 3 | 17224 | 2647 |
NUDT11,NUDT4,NUDT3 |
| 1.283e-02 | -4.36 | inositol bisdiphosphate tetrakisphosphate diphosphatase activity | molecular function | GO:0052841 | 4 | 3 | 17224 | 2647 |
NUDT11,NUDT4,NUDT3 |
| 1.283e-02 | -4.36 | bis(5'-adenosyl)-hexaphosphatase activity | molecular function | GO:0034431 | 4 | 3 | 17224 | 2647 |
NUDT11,NUDT4,NUDT3 |
| 1.283e-02 | -4.36 | inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity | molecular function | GO:0052848 | 4 | 3 | 17224 | 2647 |
NUDT11,NUDT4,NUDT3 |
| 1.283e-02 | -4.36 | inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity | molecular function | GO:0052843 | 4 | 3 | 17224 | 2647 |
NUDT11,NUDT4,NUDT3 |
| 1.283e-02 | -4.36 | endopolyphosphatase activity | molecular function | GO:0000298 | 4 | 3 | 17224 | 2647 |
NUDT11,NUDT4,NUDT3 |
| 1.285e-02 | -4.35 | protein transmembrane transport | biological process | GO:0071806 | 59 | 16 | 17256 | 2622 |
SRP72,SEC61B,TOMM20,PEX5,TIMM13,SEC61G,TIMM23,AKT2,TIMM29,TIMM17A,TIMM21,MCL1,CLU,TOMM40,C2CD5,TIMM50 |
| 1.285e-02 | -4.35 | regulation of histone methylation | biological process | GO:0031060 | 59 | 16 | 17256 | 2622 |
ZFP64,KMT2E,MECP2,RTF1,BRCA1,KDM3A,IWS1,PAF1,OGT,ZNF335,CTR9,H2AFY,KMT2B,CHTOP,SMAD4,DNMT1 |
| 1.285e-02 | -4.35 | ATP hydrolysis coupled cation transmembrane transport | biological process | GO:0099132 | 59 | 16 | 17256 | 2622 |
ATP13A1,ATP2C1,ATP6V0A1,ATP5F1B,ATP6V1B2,ATP6V0B,ATP1A1,ATP2A2,ATP5MC3,ATP13A3,ATP6V0A2,ATP6V0C,ATP5F1A,ATP6V1C1,ATP6V0E1,ATP6V0D1 |
| 1.286e-02 | -4.35 | carcinoma | COSMIC cancer mutations | carcinoma | 17358 | 2587 | 17385 | 2587 |
HECA,ZBTB10,ABCC10,HEXB,TGOLN2,CCNL2,FBXO22,EEF2K,THAP4,RAD23B,ATP13A3,DNM2,ZNRD1,FTSJ3,USP34,CCDC57,ERCC1,NRAS,EHMT1,KIF15,HNRNPF,WDHD1,MIER2,DIDO1,MCM2,RAB22A,SMAD2,MID1IP1,RPS27A,MYO18A,OGT,MPV17,COX5A,SMAD1,ZNF75A,ANXA11,SLC25A33,ZNF720,SEC61G,GGA1,MUM1,CCZ1,TRIO,CUTA,RAB23,KCTD17,HAUS4,EIF2AK4,APH1B,PARN,CDC73,MYL6B,ATG4A,TMEM179B,ERV3-1,PDXP,SMC3,C4orf3,GEMIN4,MVP,NUP85,PPP6R1,PABPC1,NSUN4,PPA1,IFRD1,AGGF1,FOXK1,RBM42,GTPBP4,MAP7D1,MRPL16,ELK1,EIF4H,RDH11,MAGED2,KPNA1,ETS2,TYW5,WIPI2,RUFY3,PDLIM5,ACSF2,FAM72D,RHOG,EXOC3,STARD7,C5orf30,VTI1A,INO80E,SLC35B2,LCLAT1,RCOR3,CPNE3,KIAA1147,RBM23,ZNF420,AHCTF1,TBC1D22A,TBC1D14,GMEB1,NSFL1C,SEPT11,ZNF226,GPD1L,ZC3H3,ARL5A,PDCL3,SNX8,ERMP1,EID1,IDH3A,POLR2D,HTATIP2,MEF2D,TMEM147,GSTCD,TANC1,MAT2A,VPS26B,NSMCE2,CORO1C,CAMKMT,PPP5C,PITRM1,TUBB,COMMD10,ZNF445,SRSF6,HABP4,CCM2,FLOT1,BTN3A1,ATG2B,ABHD14B,PPP1R3B,GOLM1,ZBTB45,HUWE1,ZNF260,NAA50,ANXA5,LTN1,KANSL2,UBE3B,NAP1L4,ZNF710,ST8SIA2,RPL22L1,MED22,SPTAN1,STAU1,DDX24,TCTEX1D2,TACC1,MRS2,LDHA,HEBP2,LLPH,C14orf132,RAB3IP,TTC33,PICALM,SH3BP5,SLC19A1,ACOX1,FAM3C,AEN,PARP10,YWHAH,THAP5,GPATCH4,FAM129A,TRIM11,YTHDC2,SNX15,RBM8A,ENSA,NENF,SND1,RUFY1,TRIM65,ZER1,PRNP,KRR1,RAB8A,NUP210,NT5DC1,NOC2L,EIF5,TACC3,RYBP,VPS13B,PTPN18,MIOS,SNRPB,MBLAC2,CDC6,UTP3,PBRM1,ODC1,USP21,TRAM2,FBXO28,BCL7C,ARRDC1,ADAM9,DVL1,NUMB,ZNF564,FUBP1,C1orf74,CTU2,PARP12,ZCCHC9,CENPF,LAMTOR3,CHCHD2,NCKAP1,LYRM2,RSAD1,TNS3,SUB1,RINL,SSBP3,KIF13B,MBD2,XPA,AHCY,RBM3,GLE1,MRPL48,LRSAM1,HDHD2,NTPCR,NSDHL,AMD1,CAMSAP1,ZNF761,METTL22,ICAM2,STYXL1,APPL1,BBS12,ANKRD46,RXRB,SDHB,PCM1,GALNT2,TMEM168,NLRC5,RUVBL2,MYO9A,BTBD10,CCNB2,USP7,GLT8D1,RPLP2,SUCLG1,ARID2,TMX4,SLC2A1,ATP6V1B2,PCBP1,LYN,BCAP31,VAV1,TMEM69,MRPL50,PSMA6,ZNF473,ZNF302,BRPF3,TARDBP,BCAP29,CTDSP2,PRPF19,PPIF,KDM3B,MND1,CLCN3,BIRC3,RAB7A,ANKRD33B,PPIE,CHMP2B,VDAC1,EIF3H,TMEM201,GLOD4,IDE,DHX16,UHRF2,XRCC3,CHMP4B,PARD3,BCL2L12,C19orf53,MCM10,KLHL21,PDAP1,TMX3,CDCA8,GTF3A,ARF1,SLC12A9,TUBGCP2,DNAJB9,HOMER1,WBP1L,POLR1B,RNF5,RBM15B,PPAN,RHOA,RPRD1A,BTAF1,TOP3A,ARHGEF12,PCGF1,DDX23,RAB18,CACNB1,TRIM26,PDCD6,ATP6V1D,L3MBTL3,FAM110A,NEIL3,CTBS,BBX,IMPDH1,TAF12,NR2F2,PGAM1,HIPK3,IFI16,NUP188,TXN,H2AFZ,PNISR,TMEM203,PRKCSH,USP39,UBE2I,PARK7,SLC25A37,ASPHD2,ZNF428,RAB4A,TRA2B,SUCLG2,CISD2,TAF5L,SMARCE1,ZNF800,CDC5L,ZNF524,SGCE,OSBP2,NSUN2,USP22,CLNS1A,EIF3A,ZMYM3,DOT1L,IWS1,ANKRD10,WAS,KIF18B,TPP2,C1orf109,ZMAT3,FAM72C,B4GALT2,PRPF38B,RECQL,C9orf78,EWSR1,GADD45G,RRM1,ACAP1,B4GALT1,CYCS,FAM136A,SUPT7L,TMEM165,NPLOC4,CNOT3,WDR48,SPAG5,RTKN,CEP104,EXOSC7,KLHL5,LRRC8D,PPP4R1,MSH2,PIGG,OSTF1,FBXL7,MRPL40,TNRC18,SYTL3,FAM171A1,APOL1,EIF5A,GCC2,PRIM2,ELL2,RDH10,MFNG,RPS24,GORASP2,CAPZA2,ADRB2,CCT8,MTR,PHF6,PFDN5,SLCO4A1,TTC13,GOLGA2,RBMX,MED15,PIAS2,APPL2,SAMD8,NUDT3,CDKN2A,ZNF511,ATXN3,RAF1,KIAA0232,C2orf49,CD320,EPM2A,CCNA2,MTMR4,BRI3,TP53BP2,AQR,RBM12B,ILKAP,CDK12,SAP30,BRD4,DRAP1,NARF,LRRC8A,ELP4,ABHD11,PKMYT1,ASB13,SERP1,TRIM28,SUPT16H,EIF3K,CHMP4A,CBWD1,ATF6,XRCC4,ADAM23,PRPF4B,NDUFS1,DEPDC1,MECP2,SECISBP2,HMG20A,WWP2,SLC25A36,JAKMIP1,CCNK,DNAJC8,ELP5,AXIN2,CITED2,JMJD4,ANKRD37,KAT2A,TMEM126B,RABIF,ADSL,PACS1,BMS1,KCNQ1,OTUD3,ARSK,MACF1,KIF11,KLF6,COMMD4,SMAP2,FADD,SH3GLB1,MYO1F,CBX3,TMEM127,INF2,PPP1R11,DUSP11,DDX5,WDR62,TAF6,ESPL1,PURA,DDB1,DEF6,FAM83G,IPO4,UBL3,PIGM,NAT9,LYRM4,GPR132,UBE2Q1,PTP4A3,BRIX1,MRPL19,ZNF696,SF3B2,PCYOX1L,CDC42,SYNM,GOT2,JAZF1,HADHB,RPF2,SLC35C2,CNNM3,CARM1,SRPK2,WDR41,LARS,ZCCHC10,CCDC138,LRBA,TMEM216,SUMF2,KMT2C,OGFR,PRPSAP1,ASF1B,RPL37,MAN2A2,EIF4ENIF1,NIP7,U2SURP,MIA2,ZNF268,VPS4A,ATP6V0E1,PPP1R2,PM20D2,XPNPEP3,RGS2,LYAR,FAM89B,POLR2I,TRAFD1,SUGP2,GBA,EIF2A,SYVN1,CCDC71L,DAPK3,ARHGAP15,MASTL,UAP1,NFIL3,FN3KRP,YWHAZ,CTSA,TMEM14A,TOB1,TSEN15,ADNP2,TCF12,PRKAB1,MDH2,SMARCA4,ORC1,RRN3,UBXN2A,IARS,CD3EAP,KIF14,EXOSC1,CS,CLTB,DNAL4,CSTF1,POU2AF1,UBQLN4,NXT1,HPDL,PGGT1B,SELPLG,SMU1,ATXN1,GLO1,OGDH,BICD2,CADM1,EDEM2,HERPUD2,TOLLIP,FANCE,MBD3,PDHX,RPS9,ALKBH6,SURF4,DUS3L,ARNTL,ANP32E,FKBP5,TMEM101,CCDC125,ABCA1,PDCD2L,GCLM,RAE1,DCTN2,NUP54,CHIC2,PAWR,MXD4,DCUN1D4,PIP4K2A,XPR1,FERMT3,KIF5B,KLHL20,SEC24C,RRBP1,ARHGEF2,ANP32A,LDLRAD3,C12orf75,STAT3,MYO5A,NIPAL3,AMPD2,TXNL1,PHF20L1,DCAF6,FAM49B,TMEM39A,ATP2C1,RFFL,COG1,RCOR1,PRMT2,TFEB,LEMD2,SERF1B,UPF1,ELMO1,ZC3H7B,DTX4,ZMIZ1,TERF1,HRAS,CCDC93,FGFR1OP,TMED7,PIGQ,AGPAT1,CNTROB,PPP1R16B,MIS12,GSDMB,TTC9C,PDS5B,NUP153,SENP1,PGAP2,TMEM115,PLEKHM3,DCUN1D5,PLEKHF2,BRMS1,PWWP2B,TRIM47,WDR11,AXIN1,SMG9,TRIM52,LONP2,NDUFV2,PHF23,CERK,SLC4A2,EZH1,ITGB5,LMNA,FBRS,MCTS1,DDX56,EIF2S2,SLC38A5,FOXN2,CARS2,PRRC2A,C16orf72,RB1CC1,ZMYND11,PGS1,MYBL2,UHRF1BP1,SRSF5,MPG,MATR3,CYB5A,NCDN,POLR2J,SETD3,TEX30,PTAR1,CNOT6,NDE1,EGLN1,ZNF207,ANKRD27,PPP1R37,ABCA3,SARNP,IVNS1ABP,MON1B,RMI2,TMEM97,NIT2,NUF2,ZNF267,TCF19,TMEM161B,KTN1,APP,PRKD3,CLUAP1,ATP2A2,UTP18,GRSF1,DUT,ZCCHC2,ANAPC7,RNF19A,FAM76B,CLN6,TMEM9,GCC1,RNF169,ADCY7,ATP6V1G1,ENPP4,RNPS1,CDCA2,FKBP3,GPR137,DDX17,CHCHD3,PEX5,CDC16,HIPK2,MBOAT1,TICAM1,PDXK,ZBTB11,ANXA6,TMBIM4,GMCL1,UBE4A,IL21R,ETS1,WRB,ZNF92,PNO1,CAPN2,ADD3,SUV39H2,TTLL12,TPCN1,TMX1,HNRNPM,LYPLA2,MFSD12,LDHB,PPP3CA,NUDT8,POLK,JTB,EMP3,MTMR12,ZP3,PDE3B,KIF18A,CCDC6,WNT5B,MAPK6,LY75,C4orf46,SLC25A19,RGL1,PSAP,WDR76,IGBP1,FAF1,SNAPIN,COX15,AGRN,THOC1,GNPDA1,GPBP1L1,PPP1R15B,CSNK2A1,EBNA1BP2,GIT2,BIRC2,ATPAF1,DLG5,ABL2,XRCC2,ZFYVE27,MCMBP,PTPRK,CDC37,SP3,METTL1,EXOSC6,HARS,GMFB,ESYT1,ANLN,RAB5B,RHEB,DPYSL3,TBC1D17,TIMM13,CDCA4,TONSL,NRM,NAGLU,ACTB,ZNF45,TMUB1,CTCF,ASAH1,DOCK11,CRLF3,ASXL2,LRRC14,NUS1,SLC27A4,AFF1,MDFIC,MAML1,CYTH1,NQO2,UTP15,EIF2AK1,EIF4G2,ZDHHC3,MOSPD3,ITPRIPL1,CDC27,SNAP23,TBPL1,PRMT7,KCTD7,NDUFA5,CYLD,UGP2,DYNLL1,COPE,HCFC1R1,ZADH2,GGPS1,RPAIN,RAD23A,ABRACL,SEC11A,PDK2,ATP6V0B,TNFAIP8,STRBP,DUS4L,MRPL34,PDCD2,SAP30L,CLPTM1,SLC39A9,RPL29,RPL35,BTG2,DNAJC9,FRAT2,MTMR6,NFATC2,KDM1B,ARL5B,USP36,CCDC127,MRPL2,ATP1A1,CLK3,MAFK,PSMD3,NDUFA11,CEP55,ZNF436,DNAJC17,NCOA1,SLC25A39,ZC3HC1,ZNF146,ATXN7L2,CDC40,SMAP1,GOLIM4,RRP15,DAP,GNE,SMC6,ARFIP2,NKRF,CHAC2,BZW2,WRNIP1,TMA7,SS18L1,CENPM,PTGES3,CAMK2G,MLEC,ZNF202,PPWD1,FAM50B,RHOT2,NEU1,TPD52L2,GOLGA7,TWSG1,GLG1,PGRMC1,FAM126A,SPCS3,RPS6KC1,UBE2C,PPCS,NDUFB6,TMEM41B,ZDHHC8,PLXNA1,CCNB1,SLC20A1,COMMD6,ABHD14A,POLR3K,C14orf119,ASAP2,SNUPN,CNPY4,TFG,PLCL2,SEH1L,ATG9A,PBK,MKI67,DDX20,AMDHD2,GALNT7,SLC17A5,CCNF,FOXRED1,RBM47,PTER,WDR4,DHTKD1,TRAF5,HDAC2,PWWP2A,HSPH1,LIME1,MAPRE1,CHTF18,ADO,KIF23,SLC35B1,NOTCH2,PMF1,COPG2,JMY,NDUFAF6,FKBP1A,SLC31A1,SNX18,ATIC,CTPS1,ATP6V0A2,PIKFYVE,RNF135,LPCAT1,EEF1D,TMED2,PHF10,FTL,DDX28,ZNF84,SIGMAR1,PIP4K2C,FAM133B,RIT1,PLEC,KDM3A,SF3A2,FAS,EPRS,ZNF777,TMEM54,QARS,PPP3R1,TCOF1,NRBP1,CABLES1,DNMT3A,RWDD1,CKLF,TRIP10,SF3B1,RPS6KA1,CAST,SUZ12,RAC1,GPR89A,OLA1,SNN,GNB2,FLAD1,APLP2,KDM2A,TNPO2,CDKN1B,TALDO1,GPX4,ATP13A1,RFC3,MAPRE2,ERF,CUL3,SLBP,KIAA1586,H2AFV,POLG2,GAR1,PSMB9,DHX57,NSA2,HSPA4,MRPL55,JAK1,TBL3,GOLGA8A,SEL1L,H2AFX,KLHDC4,B4GALT3,PDCD11,ATMIN,POLQ,POU3F2,OTUD5,NCOR2,ANKRD13D,PKP4,SCAMP3,BABAM1,CDCA3,SLC25A12,BLM,TMCC3,GTF2F1,RPL17,CRAT,AHSA1,PRC1,UPF2,COPS7B,SLC38A10,CNOT6L,CNPY3,UBE2M,IFT46,TMEM160,TSHZ1,ZFP64,STRIP1,DENND4C,DENND1B,WDR18,RPL8,ILF3,LRRC1,RHOT1,TSR2,MARK2,ECH1,PRDX1,PLD3,NUCB1,GNA12,FBXO21,C1orf131,PRDX3,PFDN4,HNRNPH3,STX18,TFDP1,KHSRP,ASNA1,CPEB2,SSSCA1,BYSL,VPS29,S100PBP,MIB2,IER2,PTMS,NOP2,UBN1,DCAF15,NF1,FLYWCH2,ALKBH5,MOGS,UBE2Z,TAF6L,BECN1,MAPK14,SNAPC4,RNF103,BCAT2,MBD4,C18orf32,METTL14,ZNHIT6,IMPAD1,RCSD1,PHTF1,SRI,KIF22,ZBTB22,NFU1,OGG1,TRIM14,ELOF1,COPS8,FYTTD1,TRIM8,RRM2,SOX4,ABHD5,UBTF,CXXC4,PAF1,UEVLD,SPATA2,PQBP1,IARS2,ATXN2L,GALNT10,STARD3NL,RPS15,PIGN,AGTRAP,CIB1,XPO7,SRRT,ZNF449,CAPZA1,GLTP,BCL2,KIFAP3,N4BP2,HP1BP3,VOPP1,THNSL1,ISG15,CAND1,C22orf46,GNAS,TSC1,RBM25,CDCA5,ZFP90,NANP,RBBP4,ZBTB24,SMARCD1,MBD1,WASF2,MMACHC,TOMM20,IFI27L1,GNPNAT1,MPHOSPH8,HNRNPUL2,CHD1,MEAF6,C2orf68,CCDC50,AKAP8,PARL,RPN2,CHTOP,FAM3A,F2R,SCYL3,TMEM14C,ABI1,HTRA2,MOSPD1,RLIM,FAM172A,ZNF500,PSMB7,NLN,WIPF1,BOLA1,BUD13,NDUFB1,PEF1,EIF3G,BTBD1,TAB2,CHCHD1,TULP3,WDR59,CANT1,SCARB1,GAS2,USP11,SMURF1,TSPAN5,PPP2R2D,CDS2,MAGEH1,MRPL42,EYA1,CDK2AP2,MRPS26,LETMD1,KLF13,HDDC2,RGS1,MAN1A1,FBXO5,GART,PELO,TANK,BRD7,MRPL11,SAMD4B,ZDHHC18,GTF3C6,POLR3GL,WDR81,MEN1,ZNF407,MFN2,COX8A,ZRANB2,MBD6,SRSF3,ATP6V1C1,IDH3B,TATDN1,TSC2,LACTB2,CMTM6,RBM4,ANKRD39,ZNF275,RPL23A,CDKN2C,NAPG,USF1,DNAAF2,MECR,AP1M1,UPRT,CRY2,ECD,RNF26,MOB1A,TIPARP,LRRC59,ANKRD9,MGAT5,RHBDD2,BAK1,ZNF559,RHOBTB3,GABPA,NUTF2,WBP1,GINS4,ARF4,KRIT1,BOLA3,AHNAK,RAD18,PDRG1,RNASEL,CHPF2,OAZ1,SMNDC1,PDCD4,NXT2,HIVEP3,KIAA0100,CLSPN,RHOC,DHX9,PDCD7,PSMD9,HAUS2,COPB2,CD59,TFAP4,RNFT1,MEGF8,RIMS3,EFTUD2,FBXO7,MRPL21,CPSF4,PHKG2,LUC7L2,SRSF11,EIF3L,MTA2,TYW1,USP10,ITM2A,SSR2,BCLAF1,MTX1,SFXN5,FNTA,PDLIM1,TXNDC16,TMEM159,ZNF830,MRPL3,ALS2,FAM72A,TRIM41,KARS,NQO1,POC1A,PTTG1,ANK3,TPX2,TBC1D13,DAZAP2,STMN1,GLRX3,C19orf48,CBWD5,REPS1,ABHD16A,FBXL6,SH3BP1,MTA1,UBA5,CLCN6,INTS12,C8orf59,RPRD1B,SZRD1,CGGBP1,CPNE1,SEC61B,POLR2L,FAM118B,GOPC,CRNKL1,E2F3,CIRBP,RPL38,PFKFB3,GORAB,RAB1A,GIGYF1,TMEM184C,PPP2CA,KIF2A,CCDC14,LSM6,RNF38,DMWD,SNRPG,CENPBD1,USP13,MZT1,ZFP91,TRMT6,IP6K2,WDR5,SLC25A43,PMVK,IFT27,RRP36,NEIL2,SRXN1,RPA2,PSMD2,CLIC4,PDCD10,ITGB8,CBWD2,COQ4,ARF5,ARHGEF1,FBXL19,GTF2H2,TTPAL,UTP20,MAGT1,GPS2,DBI,MRFAP1L1,SSNA1,CD81,TMEM131,WDR13,FANCI,PAPOLA,CREM,FANCL,TET3,GLIS2,IL6ST,INTS1,POP7,SLC44A1,MTPN,ASB6,PLK1,RPP25,CELSR2,SEPT9,RBX1,APH1A,RAD51AP1,ZBED5,CKAP2L,PSMG1,UBE2V1,IL12RB1,EAF2,KRTCAP2,LUC7L,LSG1,NECAP2,C1orf122,TRIM4,ALG3,AGPAT2,CHD3,ZNF367,E2F4,PRPF4,KPNA2,BEND6,CLN3,DNAJC30,FAM208A,NGLY1,POT1,MYL12B,CCDC137,RMND5A,HJURP,PHB2,FAM53C,DNAJB2,NKD2,SDC2,KLC1,CDK13,ADCK5,COX4I1,RAB6A,DNAJB1,ARID1B,C1GALT1,MLX,UBE2Q2,CCP110,ZNF746,ARL6IP1,CTR9,NIPSNAP1,ABHD2,DCAF8,ACSL3,LDB1,MAP4K3,ARMC8,RBM38,IRF5,NMT2,RPL36,HAUS8,MBIP,ORMDL2,COX7A2L,ZDHHC7,FAM122A,SIL1,DTD1,UNC13C,BCCIP,SART1,TRAF7,NDUFAF2,TOR1AIP1,ZNF416,LAGE3,TM9SF3,ZFYVE21,RRAGC,ZNF121,OIP5,NRF1,WDR44,PIN1,PPME1,EFCAB11,RPAP1,CABLES2,TOP1MT,LMAN1,AHCYL1,STRAP,SPSB3,ZNF583,SNX25,ARHGAP17,POLR2G,KIAA0040,ZNF780B,PPT1,NUP155,DCLRE1C,MRPS14,RHBDF2,SUGP1,RBL1,FASTK,UBXN2B,STK38,AP1S1,SPRYD4,SLC22A23,H3F3A,CHID1,SMAD4,RAD51D,SLC30A9,NADSYN1,UNK,CMAS,HMGN3,NCAPG,SCYL2,FZD6,HERC3,GTPBP3,CTSS,ORC3,RNLS,YTHDC1,ACP2,CSRP1,HMGN5,METTL5,ABCF2,TUFM,RANGAP1,PNPLA8,HAGH,API5,ZFR,SEC23IP,E2F1,USP20,TMEM219,RBPJ,MAX,PDCD6IP,LUZP1,GXYLT1,ADAM10,CXXC1,TSC22D3,AP3M2,CUL1,GYG1,NANS,OAT,MYEF2,ANKRD26,PA2G4,NOL11,FIZ1,ZNF200,MARCH2,SLC26A2,SRSF10,SRP72,KLF10,LACTB,RFC2,CBFB,RAB2B,PRIM1,MAP3K4,HHEX,RPS14,LUC7L3,MAP4,MRPL27,BTF3,PTPDC1,CCDC59,NMD3,PTOV1,COX5B,DNAJC5,SCOC,DHPS,POLR2K,ANKH,C16orf87,VAV2,PRKAA1,GSPT2,DLGAP4,TATDN3,PXMP2,PRPF39,PSEN1,ZNF79,PDXDC1,VPS25,NDUFS7,YY1AP1,C12orf10,FAM192A,RPN1,LHX8,ARPC5,ZNRF2,DAPK1,TPST1,PIK3IP1,CYC1,SOCS5,FDFT1,PIGT,WDR1,EMB,ZNF574,C1orf35,EXOSC9,ARID1A,PTTG1IP,C9orf40,FXR1,GOSR1,MAP2K2,TWISTNB,AKAP1,XRCC5,HMGN2,PI4K2A,SEC31A,CAT,DERL1,HSPBP1,MTHFD2,CEBPG,ARAP1,FAM83D,USP32,CABIN1,SMPD4,GPI,CYTIP,TP53RK,REPS2,RAB11B,UROD,SLC39A13,POMP,BCL2L1,NUDT19,DECR1,RALB,SIAH1,LPIN2,ADCY9,SOCS6,MRPS27,TTC3,RNASEH2A,CFL1,ANKLE2,CDC123,OAF,VDAC2,EDF1,ERC1,EML4,AMZ2,ANKZF1,ZNF282,RAD51C,DSN1,DDOST,HINT1,DGCR8,SAFB,HAGHL,LMBR1,FTSJ1,RWDD4,NCLN,BEND3,EYA2,DYNC1LI2,B4GALT5,SLC41A1,MANBA,TKT,FAM76A,CBLL1,ARGLU1,LANCL1,POFUT1,FAM8A1,HEATR5B,HLA-A,EBP,RFWD3,NDUFA2,FUT8,FJX1,BTF3L4,PTPN11,MRPL54,FEM1B,RPL19,CNN2,NDUFA3,MTX2,MSH6,PDLIM2,LONRF3,RFXANK,FBXO9,GUF1,RPL32,ZHX1,OAZ2,NDUFS5,WDR91,HIGD2A,GPR89B,ZBED3,RORB,POLA2,ZNF76,MTX3,COPA,UQCR10,HMGXB3,PHRF1,ABCB10,COMMD5,MAP1LC3B,DST,SIVA1,RAB35,GPATCH1,TCEA1,DRAM2,DEAF1,TRAPPC13,SNRNP200,NCK1,LAP3,VHL,SREK1,ARHGDIB,PITPNB,HSPB11,BRWD1,PPM1G,SH3GLB2,CRCP,BAZ1B,ACBD4,CAB39,STK11,CLU,CHEK2,ZSWIM3,TSTD2,MRPL13,CHPT1,DCAF5,CAPN1,UBE2D3,NSMCE4A,PPP1R12A,ZCCHC8,GORASP1,NACA,UBXN1,C19orf25,EPN1,PCSK7,RPL15,THRAP3,TTF1,QSOX2,NUP205,PRPF18,CHKA,DTL,MED10,ZRANB1,MCPH1,SLC12A2,ATP6V0D1,CSNK1G3,CREG1,NUDT4,RPL6,VKORC1,SLTM,EVC2,KLHL15,SIAH2,SLC16A1,EHD4,SNRNP70,C11orf1,APOL2,N4BP2L2,SNX27,CHMP2A,CORO7,FEZ2,PMS2,UCK2,UCK1,CLCC1,EXT2,MXD1,USP5,HNRNPA2B1,SAP130,NVL,PPP6C,CYB5R1,ZNF770,EBAG9,RNF25,PCGF6,METTL2A,FAM72B,PON2,HNRNPR,HPS5,STAT6,MAPK1,BRD9,TMEM33,PDF,NAT14,DNAJC2,TRIP12,SHPRH,SCYL1,VPS45,MYO9B,GFM2,SPPL2A,FASTKD3,FGFR3,MZT2A,PPIG,ZDHHC13,TMEM99,H2AFY,ATG13,NDUFS8,ERI3,FBL,FRMD8,SLC35A1,MICAL3,TGFB1,B3GALT6,ELOVL5,HEMK1,TIMMDC1,HELB,PSPC1,MIER1,SCFD2,NDRG3,ARL17A,CDK11A,MTMR3,MEGF9,ACAT1,CENPT,PLOD3,RAB3IL1,ZSWIM6,RAB14,ADD1,MRPS15,KDM4A,XIAP,DHX8,GLUD1,ANKRD23,PABPC4,CALM2,CDK5,PSMD1,NEK6,NSRP1,RABGAP1L,SRSF4,FNIP2,KCNAB2,PCBP2,MLST8,PLK3,ZNF672,MRPL43,HSDL1,TOPORS,MCL1,SMC2,PPFIA3,ICMT,SLC50A1,STOML2,LIMK1,ZNF689,PRDX5,ATE1,MLYCD,ATP6V0C,ST3GAL2,FBXL3,TFDP2,E2F2,PFKP,AAAS,DDX42,SSRP1,MRPL9,MRPS2,STRN4,TOP2B,ZNRF3,TMED3,DDRGK1,RAVER2,GNS,INTS7,INPP5A,MCM5,PHF14,ZNF326,UBE2QL1,NAGPA,TIMM8B,ETV3,TSPYL4,TSPAN31,DHX29,TEX10,MAN1B1,RPS10,CBFA2T2,ABCF1,RHOB,LRRC14B,DTWD1,PTPRF,SCARB2,OSBPL11,CCDC86,DUSP3,SLAIN1,MDH1,HEXA,RNF139,SNX14,ZNF296,TRERF1,UBR2,CHD1L,ACTR3,WDTC1,MYH9,CREBL2,NIPA2,PRKACA,SAFB2,ANKIB1,STAM,ARL6IP6,RAB21,SP100,ZKSCAN1,DDA1,NUP107,ANKRD13C,MAVS,CEP63,TMEM136,RBM15,ATF2,DCTN1,SHOC2,PSRC1,MAP4K4,WBP2,ATP6V0A1,NUSAP1,NDUFA7,DNAJA1,TAZ,C19orf54,TAF2,SEC61A1,WDR7,RPLP1,CBLN2,RBMS1,FUS,GEN1,LRP8,COIL,LRCH1,GALK1,ZNF786,RPS2,SESTD1,TRAK1,JMJD6,SIKE1,AKT1S1,KRI1,FBXO3,ERH,GATC,NDUFB4,PPP1R8,PRDM4,GTSE1,GEMIN6,DCP1A,SGCB,S100A6,IMPA2,NUDC,PDPK1,TK1,GUK1,TNFAIP3,GALC,ZNF512,KIAA0930,MRPS10,DDX39A,RPA1,ZNF862,ZNF180,KEAP1,POLE,TATDN2,PITX1,CAPN7,LRPPRC,PML,HMGB2,USF2,ANAPC4,SRM,DDX47,MCCC1,CDC42SE2,S1PR2,CDIPT,SEC16A,KCMF1,SSR1,LIN9,PCNA,ZNF639,TRMU,PIK3R2,ETV6,PPCDC,TXLNA,FAM86C1,MYBL1,MRPL32,CCAR1,ABCC5,PBXIP1,BAZ2A,TLK1,MRPL12,EZR,LNX2,LRP5,BRCA1,PRKRA,STX16,EPB41,OPTN,SEPT1,SOCS4,QRSL1,PIEZO1,OSGEPL1,GLCCI1,NUDT11,NAA60,GEMIN7,SEPHS2,LZTR1,RACGAP1,PPP3CB,B4GALT4,RLF,RAPGEF6,SNRNP25,RB1,VASP,MED8,VMP1,PPIL2,MEA1,TIMELESS,AHDC1,ALDH18A1,TMEM8A,ABCC1,PREB,TRAPPC9,AACS,MEMO1,KRAS,RTF1,UBE4B,NFATC2IP,LY6E,ARPC1A,ZNF174,PSMC4,GOLGA4,SYNCRIP,PALB2,PRPS2,NIPA1,TIGD2,RNF114,FOXM1,MRPL39,XAB2,SUMO2,DUSP22,COMMD8,RPL11,CSDE1,MDM2,CORO1A,MINPP1,METTL9,POC5,DVL2,GM2A,PSMA8,COQ10B,CPOX,TIGD5,SLC26A6,CYP20A1,PRPF3,TXNL4A,RPSA,SRSF1,DNAJC10,SCAP,ZNF700,PLEKHG4B,TIMM17A,TOMM6,FAU,LTA4H,AP2S1,USP53,INTS2,CTDP1,MIF4GD,CDT1,ARID5A,SUMF1,GGA2,AP3S1,CSNK1A1,RMI1,TFRC,PTPN2,STARD9,IRF4,GSTK1,NDUFV1,SLC1A4,CWC27,SLC35B4,DDX31,ABCD1,RPAP3,CNTN5,SNX2,ZMYM5,CCDC34,CHCHD6,BSDC1,KPNA4,CDKN2AIPNL,FBXO41,BIRC5,TFE3,SNAP29,CDCA7L,PKD2,ACADM,CHMP7,SAT2,GCSH,ZNF496,TMEM109,TAP1,YTHDF3,NHLRC3,IKBIP,EIF1B,ELMOD2,KIFC1,DBNDD1,CYB5RL,PARPBP,RNASEK,CDC25B,PRADC1,DNMT1,NOL12,ORAI2,USO1,AKT2,NOL8,GNG7,AURKB,MCFD2,SLC25A5,ZFAND5,MAK16,STT3A,TMED10,PSMD8,EIF2D,ITGB1,PTPN7,UQCRH,RRS1,ARRB2,RTN3,ZNF598,SVIP,DDX58,WSB2,PPIB,MUT,GMFG,HLA-E,NDUFA4,MAN2B1,METTL3,CFLAR,NDUFS4,RNF121,MEX3C,KLF16,HDAC7,DAD1,BDH1,PCYT2,GNAI2,ANKHD1,MORC3,TERF2,KCTD20,SEPT8,DCTD,PKM,TOMM40,PATL1,ADSS,SERTAD2,SERF2,ZFP92,NSF,DCK,ERGIC3,ACLY,LPCAT4,VCPIP1,YY1,PPP6R2,PPP6R3,MAP3K5,RNF14,CDK2,ZC3HAV1,SYS1,ZBTB37,URB2,EIF3D,MAGED1,KLHL18,ADPGK,SLC25A44,AP1B1,SDHA,PAIP2,PHC2,CRKL,MOAP1,TERF2IP,CYHR1,ZNF75D,SHC1,UCHL5,NAA35,TMBIM1,CCT2,CDKN2AIP,MKLN1,HMGN4,LYRM1,GALK2,CDC23,SHCBP1,AP4E1,PRDM11,VEZF1,PPP2R5A,ACYP1,STAT1,PPA2,TRIM32,RHEBL1,R3HCC1L,C1orf112,MRI1,TCF3,BRAP,AGPAT3,MYNN,SDF2L1,SPR,RAB11A,REEP5,FOXO3,MAD2L2,CCDC28A,PIP5K1C,RBM17,MAT2B,PTEN,CENPJ,TAGLN2,OSTC,CREB1,PACS2,NCOA2,SMC4,RNASEH2C,NEK7,NET1,PARP4,TBRG4,ANAPC2,RPL27A,YIF1A,SGSH,HGS,TTLL4,SLC38A7,MFAP1,CCDC69,BRWD3,ESYT2,SKA3,NPHP4,UBE2E2,HNRNPAB,PLXNC1,ST13,TMEM184B,DNAJC24,ZNF107,SLC29A1,KIF2C,AGFG1,SIRT2,FKBP2,USP48,SNRPD3,UBQLN2,CUTC,EDC3,UBLCP1,ZNF804A,RAP1A,THADA,EIF4A3,AP3S2,ATG3,DPYSL2,PPP1R12C,AKR1B1,NDUFB9,JOSD1,RP2,TTC4,TECR,ARID4A,FGFR1OP2,TIMM50,TDP1,DPM1,FOPNL,SLC16A7,WDR82,SLC25A22,STK17B,DHX15,CHAF1A,GEMIN5,COPS6,SASS6,RPS26,PSMC1,SLC12A7,TBC1D12,TM9SF4,ZNF768,UFC1,MED13L,TIA1,MEF2A,EPHX2,PITHD1,RHBDD1,NFATC3,BANF1,BUD31,ZNF335,YBX1,KNTC1,ACAD8,UBE3C,ZNF189,ALDH9A1,KDELR1,TSTA3,CIC,OXR1,PSMA1,TMEM241,SEPT7,NAP1L1,NSMF,ODF2,EXOC4,KIAA1328,NUP62,PITPNA,NAA20,PTDSS1,MZT2B,PDSS2,C7orf26,TMEM106C,IMMT,ASH1L,CHERP,WDYHV1,PLAGL2,CHKB,IRF3,TWF2,PAIP1,ANKRD28,ANKLE1,FARSA,SAR1A,SCAMP4,APOOL,PDIA6,ACSL5,TOR1AIP2,AZI2,GFER,RAD54B,TMEM41A,DAP3,ZNF317,GADD45B,AKNA,REEP4,CBX4,MIF,KIF3B,GOLPH3L,SH2D3A,CASP6,TOR3A,SRGN,DBF4,MFSD10,SAC3D1,CTNNBL1,YIF1B,CLDND1,TTC17,SLC25A1,GINS1,PAQR6,CSNK1G2,TELO2,ADAM17,HMGN1,NASP,ASPM,PPP1R21,PRKAR1B,SYMPK,TARS,SNRPA,MAPK3,HSPA1B,HLA-B,ATAD2,PLAA,ZNF330,OSBPL8,KBTBD7,PREPL |
| 1.288e-02 | -4.35 | V$COUP_01 | MSigDB lists | V$COUP_01 | 243 | 50 | 17377 | 2626 |
PTMS,DNMT3A,NDUFS1,PHB2,PRKCSH,SRSF6,AP1B1,DOCK11,IL21R,RNF103,LMNA,FAM192A,FGFR3,EXOSC7,SHC1,MED8,NEK6,MTMR4,RRBP1,TIMELESS,NDUFA3,RPRD1B,TPCN1,DCTN1,MLST8,MLEC,BAZ2A,CIC,NET1,SCFD2,ADRB2,PLEC,PRKRA,PDE3B,SYMPK,ZDHHC3,MARK2,NCDN,STOML2,MRPL2,GOLGA4,DUSP3,ZNF436,RBMS1,FKBP5,NR2F2,ZSWIM3,SNRNP70,PURA,DDB1 |
| 1.288e-02 | -4.35 | GO_REGULATION_OF_NEURON_DEATH | MSigDB lists | GO_REGULATION_OF_NEURON_DEATH | 243 | 50 | 17377 | 2626 |
GCLM,DNAJC5,NQO1,NF1,MECP2,PAWR,AKT1S1,BCL2L1,PSEN1,FOXO3,PARK7,CDK5,CDC42,HDAC7,KIF14,PIN1,XRCC2,ZNF746,MSH2,BCL2,CORO1A,TP53BP2,CREB1,F2R,ATF2,STAT3,UBE2M,HTRA2,SRPK2,SIGMAR1,PPT1,BTG2,OXR1,KRAS,MCL1,ELK1,PICALM,TSC1,CHMP4A,HIPK2,CHMP4B,ROCK1,GPI,CLU,MAP3K5,PPP5C,CLN3,BTBD10,PSMC1,HRAS |
| 1.291e-02 | -4.35 | positive regulation of gene expression, epigenetic | biological process | GO:0045815 | 79 | 20 | 17256 | 2622 |
KAT2A,POLR2L,POLR2K,SF3B1,WBP2,ARID1A,SLC50A1,ARID1B,TWISTNB,ATAD2,CD3EAP,KMT2B,BAZ1B,H2AFY,ACTB,POLR1B,H3F3A,ZNRD1,SMARCD1,ELOF1 |
| 1.292e-02 | -4.35 | LAMP1 (lysosomal associated membrane protein 1) | protein interactions | 3916 | 42 | 13 | 17029 | 2761 |
EWSR1,PLAA,TNFAIP3,TM9SF4,SLC38A7,FAM207A,RAB4A,FAM3C,AP1M1,ILF3,ANAPC7,STK17B,SVIP |
| 1.292e-02 | -4.35 | NDUFAF4 (NADH:ubiquinone oxidoreductase complex assembly factor 4) | protein interactions | 29078 | 42 | 13 | 17029 | 2761 |
NUDT19,NDUFA5,TIMMDC1,DHX9,HNRNPF,NDUFS8,NDUFS5,PITRM1,EYA2,DHX15,ECH1,HTRA2,NDUFS7 |
| 1.292e-02 | -4.35 | Haus1 (HAUS augmin-like complex, subunit 1) | protein interactions | 225745 | 42 | 13 | 17029 | 2761 |
GNAS,SEC61B,PCM1,HAUS4,CYC1,EFL1,ALDH18A1,GNAI2,YWHAH,SENP1,GNB2,HAUS2,HAUS8 |
| 1.292e-02 | -4.35 | ZC3H15 (zinc finger CCCH-type containing 15) | protein interactions | 55854 | 42 | 13 | 17029 | 2761 |
MRPL50,STAU1,HMGN5,THOC1,TM9SF4,ZCCHC8,ABCF2,CSNK2A1,KRAS,PHKG2,FAF1,ISG15,DCTN1 |
| 1.292e-02 | -4.35 | NEUROG3 (neurogenin 3) | protein interactions | 50674 | 42 | 13 | 17029 | 2761 |
TCF12,PHF10,DDX56,ZNF496,FAM207A,ASPM,TCF3,TEX10,MYO9B,CCDC71L,FBL,DHX57,YY1AP1 |
| 1.292e-02 | -4.35 | MGRN1 (mahogunin ring finger 1) | protein interactions | 23295 | 42 | 13 | 17029 | 2761 |
UBE2D3,HSPA4,ATXN3,INTS7,TIMM29,MEGF8,HSDL1,PDCD2,UBE2I,C9orf40,TAZ,ANKRD46,PTPRK |
| 1.292e-02 | -4.35 | RALYL (RALY RNA binding protein like) | protein interactions | 138046 | 42 | 13 | 17029 | 2761 |
YTHDC1,CDC40,EWSR1,TRAF7,XAB2,VHL,PPIE,CRNKL1,AEN,RBM3,AQR,PRKRA,BYSL |
| 1.292e-02 | -4.35 | TTC27 (tetratricopeptide repeat domain 27) | protein interactions | 55622 | 42 | 13 | 17029 | 2761 |
CCT2,SNRNP200,EFTUD2,TXLNA,PTP4A3,KRAS,ARMH3,ECD,NMD3,DHX15,NCDN,MAPK3,CSTF1 |
| 1.292e-02 | -4.35 | DCAF11 (DDB1 and CUL4 associated factor 11) | protein interactions | 80344 | 42 | 13 | 17029 | 2761 |
PLK1,COPS8,CCT2,PTEN,DCAF8,DDA1,LRBA,SLBP,MICU2,COPS7B,COPS6,EYA2,DDB1 |
| 1.292e-02 | -4.35 | POLR2I (RNA polymerase II subunit I) | protein interactions | 5438 | 42 | 13 | 17029 | 2761 |
CDKN2AIP,MED10,POLR2G,POLR2L,POLR2K,ELOA,POLR2D,BRCA1,POLR1B,PSMB9,RPRD1B,WDR48,POLR2A |
| 1.293e-02 | -4.35 | alpha-mannosidase activity | molecular function | GO:0004559 | 14 | 6 | 17224 | 2647 |
MAN2A2,MAN2B1,EDEM2,MAN1B1,MAN1A1,USF3 |
| 1.293e-02 | -4.35 | DNA replication origin binding | molecular function | GO:0003688 | 14 | 6 | 17224 | 2647 |
MCM10,ORC3,MCM2,MCM5,KAT7,DHX9 |
| 1.294e-02 | -4.35 | GO_NUCLEAR_HETEROCHROMATIN | MSigDB lists | GO_NUCLEAR_HETEROCHROMATIN | 31 | 10 | 17377 | 2626 |
DNMT3A,H2AFZ,MPHOSPH8,SUZ12,UHRF2,H2AFY,SIRT2,BEND3,TRIM28,CBX3 |
| 1.294e-02 | -4.35 | GO_CYTOPLASMIC_STRESS_GRANULE | MSigDB lists | GO_CYTOPLASMIC_STRESS_GRANULE | 31 | 10 | 17377 | 2626 |
STAU1,CIRBP,ATXN2L,PQBP1,KHSRP,TIA1,YBX1,PABPC1,RBM4,PABPC4 |
| 1.294e-02 | -4.35 | REACTOME_GPVI_MEDIATED_ACTIVATION_CASCADE | MSigDB lists | REACTOME_GPVI_MEDIATED_ACTIVATION_CASCADE | 31 | 10 | 17377 | 2626 |
PDPK1,VAV1,RHOG,RHOA,CDC42,AKT2,RAC1,PIK3R2,LYN,RHOB |
| 1.294e-02 | -4.35 | DIRMEIER_LMP1_RESPONSE_LATE_DN | MSigDB lists | DIRMEIER_LMP1_RESPONSE_LATE_DN | 31 | 10 | 17377 | 2626 |
ASAH1,RPL29,ARHGDIB,PSAP,WAS,FAU,PSMB9,ARF5,ISG15,COX8A |
| 1.294e-02 | -4.35 | BIOCARTA_EGF_PATHWAY | MSigDB lists | BIOCARTA_EGF_PATHWAY | 31 | 10 | 17377 | 2626 |
SHC1,JAK1,STAT6,RAF1,STAT1,CSNK2A1,ELK1,STAT3,HRAS,MAPK3 |
| 1.294e-02 | -4.35 | GO_REGULATION_OF_MITOCHONDRION_ORGANIZATION | MSigDB lists | GO_REGULATION_OF_MITOCHONDRION_ORGANIZATION | 198 | 42 | 17377 | 2626 |
UBE2D3,ZBED3,ZDHHC8,DYNLL1,STARD7,PLAGL2,BCL2L1,BECN1,MAP1LC3B,PARK7,APOPT1,LMNA,MOAP1,HUWE1,SIVA1,PARL,BCL2,ATG13,CYB5R1,TP53BP2,NSUN4,HTRA2,BAK1,PPIF,KAT2A,PSMB7,ADRB2,VDAC1,SLC25A5,SH3GLB1,USP36,STOML2,INF2,PSMD8,TFDP1,PPP3R1,E2F1,LRPPRC,YWHAZ,YWHAH,ARRB2,CDKN2A |
| 1.297e-02 | -4.34 | FOXA3 (forkhead box A3) | protein interactions | 3171 | 51 | 15 | 17029 | 2761 |
RPA2,RB1,NSF,KLF16,AKAP8,STAT1,NUP107,ST3GAL2,CORO1A,SMPD4,TOMM40,DDX39A,NCAPG,HDAC2,WRNIP1 |
| 1.297e-02 | -4.34 | FGFR1OP2 (FGFR1 oncogene partner 2) | protein interactions | 26127 | 51 | 15 | 17029 | 2761 |
MOB4,PPP2CA,PDCD10,NDUFS1,SURF4,PHB2,STRIP1,POC1A,MAP4K4,STRN4,SIKE1,ICE2,ZRANB1,VDAC1,CCT8 |
| 1.297e-02 | -4.34 | NLRP3 (NLR family pyrin domain containing 3) | protein interactions | 114548 | 51 | 15 | 17029 | 2761 |
ARHGAP17,FBXL6,CCDC86,LTBP4,FBXO28,SH3BP1,PHRF1,LUC7L3,SNRPB,PHF14,MCFD2,LUC7L,GPATCH4,FAF1,CBX3 |
| 1.297e-02 | -4.34 | ATP5MG (ATP synthase membrane subunit g) | protein interactions | 10632 | 51 | 15 | 17029 | 2761 |
RPN1,ATP1A1,PCM1,DDOST,SCAMP3,PHB2,MYH9,CYC1,ATP5F1B,ATP5F1A,CLN3,LMAN1,CDK2,POC5,SSR1 |
| 1.297e-02 | -4.34 | GTF2E1 (general transcription factor IIE subunit 1) | protein interactions | 2960 | 51 | 15 | 17029 | 2761 |
EWSR1,HARS,OXR1,EFTUD2,NSUN2,SH3GLB2,BRCA1,TCEA1,SND1,CBFA2T2,TAF6,APP,POLR2A,SRPK2,GTF2F1 |
| 1.299e-02 | -4.34 | positive regulation of intracellular transport | biological process | GO:0032388 | 197 | 42 | 17256 | 2622 |
UBE2D3,TM9SF4,PRKAA1,ANK3,DHX9,CIB1,PRKACA,SEC16A,MAPK14,PSEN1,BCAP31,SPAG5,PRNP,MIEF1,KIF5B,CDK5,RAB21,PDCD10,MDM2,HUWE1,PIK3R2,GTSE1,ATG13,MAVS,HTRA2,CHP1,TGFB1,PLK3,AKT2,EZR,NUTF2,EDEM2,TRIM28,USP36,SH3GLB1,PCM1,STX18,OAZ2,RUFY3,MAPK1,C2CD5,OAZ1 |
| 1.301e-02 | -4.34 | cyclin-dependent protein serine/threonine kinase activity | molecular function | GO:0004693 | 35 | 11 | 17224 | 2647 |
CCNK,CDK5,CDKN1B,CDK13,CDK11B,CCNB1,CCNB2,CDK2,CDK11A,CDK12,PRPF4B |
| 1.301e-02 | -4.34 | positive regulation of DNA biosynthetic process | biological process | GO:2000573 | 64 | 17 | 17256 | 2622 |
CCT2,RFC3,NEK7,CHTF18,AURKB,RFC2,PARN,CCT8,MAPK3,XRCC5,MAP3K4,HNRNPA2B1,NVL,PTGES3,MAPK1,ARRB2,POT1 |
| 1.304e-02 | -4.34 | GO_REGULATION_OF_PROTEIN_LOCALIZATION | MSigDB lists | GO_REGULATION_OF_PROTEIN_LOCALIZATION | 905 | 161 | 17377 | 2626 |
ZBED3,RAB14,TXN,NF1,ZDHHC8,ENSA,GLUD1,SIRT2,CCNB1,BECN1,MAPK14,PARK7,PRNP,CDK5,RAB8A,RAP1A,CDC42,RABGAP1L,PIK3R2,SRI,OGG1,KCNAB2,PLK3,PLK1,TRIM8,AKT2,EZR,LRP5,BRCA1,NUTF2,SOX4,SLC25A5,TONSL,PSMD8,AXIN1,MYO18A,ITGB1,OGT,ADAM9,STK11,ZNF268,VPS4A,DVL1,OAZ1,NUMB,SVIP,DDX58,UBE2D3,HSPH1,HLA-E,DNAJB2,NKD2,CIB1,RAB23,RACGAP1,PPP3CB,PSMD9,SPAG5,LMNA,FKBP1A,RB1,FAM89B,BCL2,MDFIC,GCC2,AACS,ACSL3,CCT8,APPL1,AKAP1,GNAS,PCM1,KPNA1,CSK,CDCA5,PPP3R1,SLC16A1,NUP62,YWHAZ,RUFY3,CDKN2A,RHOG,CYLD,CHERP,NDUFAF2,RAB11B,DYNLL1,SLC2A1,ANK3,STARD7,PLAGL2,IRF3,BCL2L1,LYN,PRKACA,BCAP31,MDM2,SP100,RALB,PIN1,PARL,TARDBP,TP53BP2,CYB5R1,MAVS,GPD1L,F2R,TMBIM1,HTRA2,CCT2,KAT7,GOPC,PSMB7,CADM1,DNAJA1,EDEM2,SERP1,TRIM28,USP36,RHBDF2,PPP2R5A,ARNTL,SMAD4,MIF,GOLPH3L,SRGN,NUP54,HMGN3,ARF1,RAB11A,WWP2,KIF5B,HUWE1,AXIN2,PTPN11,ANXA5,H2AFY,GTSE1,ATG13,HNRNPM,TGFB1,PDPK1,PPP3CA,RHOA,KAT2A,RANGAP1,BORA,PICALM,SH3GLB1,PRDX1,NUCB1,KEAP1,TFDP1,OAZ2,PML,E2F1,PKD2,YWHAH,PARP10,TERF1,FAF1 |
| 1.306e-02 | -4.34 | RNA methylation | biological process | GO:0001510 | 69 | 18 | 17256 | 2622 |
METTL1,NOP2,TRMT6,NSUN2,METTL2A,METTL3,GTPBP3,THADA,CMTR2,METTL14,WDR4,FTSJ1,TRMT10B,FBL,NSUN4,FTSJ3,MRM3,MRM2 |
| 1.307e-02 | -4.34 | skull | COSMIC cancer mutations | skull | 27 | 9 | 17385 | 2587 |
GNAS,RB1,KRAS,EWSR1,NRAS,H3F3A,PTEN,HRAS,CDKN2A |
| 1.307e-02 | -4.34 | hip | COSMIC cancer mutations | hip | 27 | 9 | 17385 | 2587 |
GNAS,FGFR3,EWSR1,NRAS,H3F3A,NF1,HRAS,AXIN2,PTPN11 |
| 1.307e-02 | -4.34 | schwannoma | COSMIC cancer mutations | schwannoma | 27 | 9 | 17385 | 2587 |
EWSR1,NF1,PTEN,ETV6,STK11,KRAS,FUS,HRAS,CDKN2A |
| 1.309e-02 | -4.34 | SERPINB5 (serpin family B member 5) | protein interactions | 5268 | 84 | 22 | 17029 | 2761 |
PPIF,RHOA,RAB11B,TKT,KRAS,EIF2A,HDGFL2,CBFB,ISG15,GLOD4,GOLGA4,EIF2S2,PALB2,UCHL5,ATIC,NAA50,KHDC4,MDH1,STK11,XRCC3,ZRANB2,SMAD4 |
| 1.309e-02 | -4.34 | RCHY1 (ring finger and CHY zinc finger domain containing 1) | protein interactions | 25898 | 84 | 22 | 17029 | 2761 |
UBE2D3,TRIM8,BIRC3,COPE,NKD2,PLAGL2,KRAS,GORAB,BRCA1,DCUN1D5,RAB11A,RBM38,ARF4,KRIT1,MDM2,RPLP1,CDKN1B,RPN2,CHEK2,TMEM14C,TMBIM1,CAMK2G |
| 1.309e-02 | -4.34 | DDX6 (DEAD-box helicase 6) | protein interactions | 1656 | 84 | 22 | 17029 | 2761 |
TIMM8B,ARHGAP17,CUL3,BRCA1,PPWD1,MCM2,COMMD4,PATL1,EDC3,CAND1,CRKL,EIF4ENIF1,TIMM13,GOLGA2,GRK2,LRPPRC,ATXN2L,DCP1A,TARDBP,AFF1,SRPK2,CDC5L |
| 1.310e-02 | -4.34 | GO_TRANSFORMING_GROWTH_FACTOR_BETA_RECEPTOR_SIGNALING_PATHWAY | MSigDB lists | GO_TRANSFORMING_GROWTH_FACTOR_BETA_RECEPTOR_SIGNALING_PATHWAY | 95 | 23 | 17377 | 2626 |
TGFB1,RHOA,KLF10,DUSP22,ITGB5,FKBP1A,SMAD2,FNTA,RPS27A,MTMR4,HIPK2,FUT8,ITGB1,PML,ADAM9,CREB1,SMAD1,SMURF1,ARRB2,UBE2M,SMAD4,PARD3,PTPRK |
| 1.310e-02 | -4.33 | Spliceosome, U1-snRNP | KEGG pathways | hsa_M00351 | 10 | 5 | 7161 | 1149 |
SNRPG,SNRPD3,SNRNP70,SNRPB,SNRPA |
| 1.310e-02 | -4.33 | Spliceosome, U1-snRNP | KEGG pathways | M00351 | 10 | 5 | 7161 | 1149 |
SNRPG,SNRPD3,SNRNP70,SNRPB,SNRPA |
| 1.311e-02 | -4.33 | GSE26030_TH1_VS_TH17_DAY5_POST_POLARIZATION_DN | MSigDB lists | GSE26030_TH1_VS_TH17_DAY5_POST_POLARIZATION_DN | 187 | 40 | 17377 | 2626 |
HIVEP3,PPCS,RRP15,VAV2,MOGS,UBE2I,WDR5,BZW2,PIP4K2A,REPS1,CHKA,EEF2K,SLC31A1,GART,IARS,SNX18,ATIC,SLC44A1,ARL6IP1,ATP6V0A2,SEPT11,SUCLG2,GEMIN4,PPA1,CARM1,ABCC1,CDC5L,ADAM17,TK1,NSUN2,EZR,IL12RB1,ALG3,FAM110A,GRIPAP1,FKBP5,PDXK,ABCA1,BYSL,PFKP |
| 1.311e-02 | -4.33 | GSE9650_NAIVE_VS_EFF_CD8_TCELL_UP | MSigDB lists | GSE9650_NAIVE_VS_EFF_CD8_TCELL_UP | 187 | 40 | 17377 | 2626 |
SLC12A7,DDX47,MAX,CHERP,DNAJB2,NIT2,DNAJB1,C19orf48,CRLF3,APP,CTSS,IL6ST,SLC44A1,TTC3,CYB5R1,POLR1B,METTL9,ABCC5,USP34,CAMSAP1,RPL6,USP10,PSMG1,MAP4K3,RAB3IP,VKORC1,HAGH,RBM38,ANKRD10,ZNF282,PCM1,ETS2,ACYP1,RNF38,SMAD1,HEXA,EYA2,IPO4,HDAC2,PTOV1 |
| 1.311e-02 | -4.33 | GSE24634_NAIVE_CD4_TCELL_VS_DAY5_IL4_CONV_TREG_UP | MSigDB lists | GSE24634_NAIVE_CD4_TCELL_VS_DAY5_IL4_CONV_TREG_UP | 187 | 40 | 17377 | 2626 |
CYTIP,HECA,HLA-E,CXXC1,FAM53C,BTN3A1,COX4I1,CHKB,DAZAP2,SNN,FAM8A1,RPL11,GTF2F1,SLC25A36,TPST1,RPL19,BCL2,FAM171A1,NCOA2,SPSB3,ATP6V1G1,NOL12,CYTH1,RPL29,RPS10,PACS1,SRSF5,CBFA2T2,STX16,MAGED2,SGSH,RPL32,RPS14,GADD45B,ARNTL,PQBP1,RNF38,TOB1,PPP2R2D,RNF139 |
| 1.311e-02 | -4.33 | GSE15659_NONSUPPRESSIVE_TCELL_VS_ACTIVATED_TREG_DN | MSigDB lists | GSE15659_NONSUPPRESSIVE_TCELL_VS_ACTIVATED_TREG_DN | 187 | 40 | 17377 | 2626 |
SEPHS2,UBL3,ZCCHC9,TRIP12,SLC41A1,TOR1AIP1,RRM1,TOP2B,SLC4A2,RLF,PSEN1,SEC11A,RPN1,PSMA6,ZNRF2,RAB35,SUCLG2,YIF1B,TTC4,RNF19A,TMBIM1,USP34,SEC61B,TK1,TNFAIP3,TSTA3,ZMYND11,TOP3A,RCOR1,RIT1,UBE4B,PRKRA,ZFAND5,TTC33,RAB2B,SMAP2,ROCK1,USP11,YY1,SMAD1 |
| 1.311e-02 | -4.33 | GSE17721_0.5H_VS_24H_LPS_BMDC_UP | MSigDB lists | GSE17721_0.5H_VS_24H_LPS_BMDC_UP | 187 | 40 | 17377 | 2626 |
TRIM11,TKT,THRAP3,FKBP1A,CDKN2C,LYAR,STRBP,ATG3,PPP4R1,SOCS6,AKR1B1,CENPM,CORO1A,ALDH18A1,MRPL21,NUDC,VOPP1,TK1,RBM42,LAP3,GALC,ASPM,DNAJC9,ABCF1,HAUS8,SUPT16H,TFEB,HHEX,GALNT2,QARS,RPS14,DCAF11,QRSL1,CENPT,PDXK,GLCCI1,TSPAN5,HIGD2A,AAAS,TMEM131 |
| 1.311e-02 | -4.33 | GSE17721_CPG_VS_GARDIQUIMOD_4H_BMDC_UP | MSigDB lists | GSE17721_CPG_VS_GARDIQUIMOD_4H_BMDC_UP | 187 | 40 | 17377 | 2626 |
ARID2,TOR3A,TBC1D13,NOTCH2,B4GALT4,RGS1,CRKL,LIN9,CDKN2C,ZNF428,NUS1,SSBP3,MBD2,SOCS6,TIMELESS,PLCL2,SAP30,TIMP2,ZMYND11,SMU1,FRAT2,AZI2,TANC1,OGFR,ODC1,ABCF1,RAB22A,SOCS7,HLA-B,HHEX,TMEM168,TMEM54,QARS,PPP3R1,LY75,SRSF3,NDE1,RUFY3,FBXL3,NMD3 |
| 1.311e-02 | -4.33 | GSE46143_CTRL_VS_LMP2A_TRANSDUCED_CD10_POS_GC_BCELL_DN | MSigDB lists | GSE46143_CTRL_VS_LMP2A_TRANSDUCED_CD10_POS_GC_BCELL_DN | 187 | 40 | 17377 | 2626 |
TMEM106C,TRIM41,ASH1L,SYS1,GMFG,CAST,TM9SF3,CDC42SE2,GYG1,REEP5,COPB2,UBLCP1,MBD4,TMEM179B,ANKRD28,PSMD1,AP3S2,RABGAP1L,GRSF1,TTC3,COPS7B,S100A6,PPP3CA,MIOS,DPM1,RBX1,EMB,HELB,ITM2A,ARID1A,PTTG1IP,LY6E,AHNAK,PDCD6,POLR2J,DDOST,PITPNA,SRSF3,GAS2,SASS6 |
| 1.311e-02 | -4.33 | GSE12198_CTRL_VS_LOW_IL2_STIM_NK_CELL_DN | MSigDB lists | GSE12198_CTRL_VS_LOW_IL2_STIM_NK_CELL_DN | 187 | 40 | 17377 | 2626 |
GCLM,RPS2,UFC1,SCYL1,BABAM1,GLRX3,MIEN1,METTL3,PAPOLA,SNRNP25,SLC31A1,SAR1A,BTF3L4,PTPN11,EI24,UBE3C,ERI3,AHCYL1,NAA35,PLK3,HEMK1,TMEM39A,CPOX,TMEM216,GLO1,THNSL1,SMC2,METTL22,C9orf40,GOLGA7,STX18,NUP62,DTD1,TMEM101,SNRPG,NAA20,CHID1,NMD3,CDKN2A,DDB1 |
| 1.311e-02 | -4.33 | GSE13306_LAMINA_PROPRIA_VS_SPLEEN_TREG_UP | MSigDB lists | GSE13306_LAMINA_PROPRIA_VS_SPLEEN_TREG_UP | 187 | 40 | 17377 | 2626 |
KIF3B,PARP12,FAM129A,UBE2Q1,CREBL2,CDC42SE2,DAZAP2,RGS2,MAP1LC3B,LCLAT1,EXT2,UBLCP1,KIF5B,RABGAP1L,SLC44A1,AFF1,CREB1,SPSB3,C16orf72,RB1CC1,KIAA0040,COQ10B,TMEM216,DOT1L,VEZF1,TMEM127,TRAM2,PON2,UPF1,RBL1,ZHX1,MFAP1,HIPK2,ANP32E,FBXL3,GLCCI1,TOB1,HIPK3,SLC25A33,SMARCD1 |
| 1.311e-02 | -4.33 | GSE360_DC_VS_MAC_L_MAJOR_UP | MSigDB lists | GSE360_DC_VS_MAC_L_MAJOR_UP | 187 | 40 | 17377 | 2626 |
UBL3,NCOR2,IMMT,MAPRE1,MDH2,GADD45G,SMARCA4,CREBL2,ORC1,PPP1R16B,REEP5,KTN1,PDCD10,PIN1,RBM34,CRAT,CDKN1B,CYC1,MARCH2,MINPP1,PABPC1,NIPSNAP1,PTPRK,NIPAL3,PTPN18,KCTD20,HTATIP2,MTMR6,SOX4,HAGH,UPF1,SCAP,TONSL,PFDN4,NAGLU,PGRMC1,COX5A,HMGB2,TFDP2,SSRP1 |
| 1.311e-02 | -4.33 | vesicle transport along microtubule | biological process | GO:0047496 | 40 | 12 | 17256 | 2622 |
KIF5B,KIF3B,AP3S2,TRAK1,AP3M2,KIF23,KIFAP3,NDE1,RAB1A,CLN3,AP3S1,SNAPIN |
| 1.311e-02 | -4.33 | protein destabilization | biological process | GO:0031648 | 40 | 12 | 17256 | 2622 |
DERL1,PLK1,MDM2,SIAH1,PRKDC,CUL3,FBXL3,RNF139,CDC73,RNF5,PRNP,RAD23A |
| 1.311e-02 | -4.33 | negative regulation of G0 to G1 transition | biological process | GO:0070317 | 40 | 12 | 17256 | 2622 |
MAX,SUZ12,EHMT1,TFDP1,PCGF6,E2F1,RRM2,BRCA1,RBBP4,TFDP2,RYBP,CBX3 |
| 1.313e-02 | -4.33 | TLK1 (tousled like kinase 1) | protein interactions | 9874 | 25 | 9 | 17029 | 2761 |
DYNLL1,SNAP23,TLK1,PTPN11,UHRF2,NFATC2,UBE3C,XPO7,ASF1B |
| 1.313e-02 | -4.33 | CSN2 (casein beta) | protein interactions | 1447 | 25 | 9 | 17029 | 2761 |
PLK1,NEK1,CDC42,RAC1,CSNK2A1,CUL1,ARRB2,TOLLIP,HTRA2 |
| 1.313e-02 | -4.33 | NIT2 (nitrilase family member 2) | protein interactions | 56954 | 25 | 9 | 17029 | 2761 |
TMED10,PPT1,PRDX5,TOR1AIP1,MRPL12,LDHA,CREB1,PARK7,LDHB |
| 1.313e-02 | -4.33 | TINAG (tubulointerstitial nephritis antigen) | protein interactions | 27283 | 25 | 9 | 17029 | 2761 |
PPP2CA,CTU2,IDE,TRAF7,CUL1,BOLA1,GFER,TERF1,ZNF696 |
| 1.313e-02 | -4.33 | PTPRN2 (protein tyrosine phosphatase, receptor type N2) | protein interactions | 5799 | 25 | 9 | 17029 | 2761 |
ANKLE2,TELO2,UBQLN4,HGS,GOLGA4,SEC61A1,NUP155,CLCC1,STAM |
| 1.313e-02 | -4.33 | HIST1H3B (histone cluster 1 H3 family member b) | protein interactions | 8358 | 25 | 9 | 17029 | 2761 |
H2AFZ,BANF1,H2AFX,H2AFY,MCM2,RBBP4,CREB1,ASF1B,CHAF1A |
| 1.313e-02 | -4.33 | HSP90AB2P (heat shock protein 90 alpha family class B member 2, pseudogene) | protein interactions | 391634 | 25 | 9 | 17029 | 2761 |
CAMKMT,CUL3,CUL1,BRCA1,MCM2,METTL22,TERF1,CAND1,TERF2 |
| 1.313e-02 | -4.33 | MYCN (MYCN proto-oncogene, bHLH transcription factor) | protein interactions | 4613 | 25 | 9 | 17029 | 2761 |
MAX,HUWE1,LRPPRC,CSNK2A1,TRIM32,WDR5,CDKN2A,HDAC2,MXD1 |
| 1.313e-02 | -4.33 | Rock1 (Rho-associated coiled-coil containing protein kinase 1) | protein interactions | 19877 | 25 | 9 | 17029 | 2761 |
PSRC1,RHOA,CDC42,STX18,SMARCA4,ATP6V0A2,CDK2,UBE2M,GPATCH4 |
| 1.313e-02 | -4.33 | INTS10 (integrator complex subunit 10) | protein interactions | 55174 | 25 | 9 | 17029 | 2761 |
INTS2,PPP2CA,INTS7,INTS1,RAF1,INTS13,POLR2D,INTS12,POLR2A |
| 1.313e-02 | -4.33 | NDUFB6 (NADH:ubiquinone oxidoreductase subunit B6) | protein interactions | 4712 | 25 | 9 | 17029 | 2761 |
SDHB,NDUFV1,TIMMDC1,NDUFA11,MPV17,NDUFS5,IKBIP,APP,NDUFS7 |
| 1.313e-02 | -4.33 | KCTD12 (potassium channel tetramerization domain containing 12) | protein interactions | 115207 | 25 | 9 | 17029 | 2761 |
EWSR1,PCM1,KPNA1,GABPA,GNE,ARAP1,CUL3,KRAS,LMNA |
| 1.313e-02 | -4.33 | ORF4 (complement control protein) | protein interactions | 4961488 | 25 | 9 | 17029 | 2761 |
NOP9,TNPO3,TNPO2,TBRG4,XPO7,UBE3C,BZW2,CIP2A,CAND1 |
| 1.313e-02 | -4.33 | RHOG (ras homolog family member G) | protein interactions | 391 | 25 | 9 | 17029 | 2761 |
VAV1,ELMO1,RAB7A,VAV2,TRIO,SMAD1,ELMOD2,KTN1,SMAD4 |
| 1.313e-02 | -4.33 | IL24 (interleukin 24) | protein interactions | 11009 | 25 | 9 | 17029 | 2761 |
PALB2,PTEN,RB1CC1,KRAS,NOTCH2,CLU,CHEK2,HRAS,SMAD4 |
| 1.313e-02 | -4.33 | RIPK3 (receptor interacting serine/threonine kinase 3) | protein interactions | 11035 | 25 | 9 | 17029 | 2761 |
BIRC3,XIAP,FKBP5,TICAM1,BIRC2,FADD,SRPK2,PTPRK,CDC37 |
| 1.313e-02 | -4.33 | ZBTB44 (zinc finger and BTB domain containing 44) | protein interactions | 29068 | 25 | 9 | 17029 | 2761 |
USP7,PSMA6,KLHL20,KLHL21,TRIM11,AP1M1,SMAD1,GLRX3,RAD23A |
| 1.313e-02 | -4.33 | CELF1 (CUGBP Elav-like family member 1) | protein interactions | 10658 | 25 | 9 | 17029 | 2761 |
RPA2,KIF2A,CERK,USP10,TARDBP,APP,MAPK3,FUBP1,RPA1 |
| 1.313e-02 | -4.33 | TRO (trophinin) | protein interactions | 7216 | 25 | 9 | 17029 | 2761 |
GNAS,USP7,RPS2,ARPC5,RABGAP1L,DNAJB2,IRF3,FBL,BYSL |
| 1.318e-02 | -4.33 | Regulation of retinoblastoma protein | Pathway Interaction DB | rb_1pathway | 56 | 18 | 2226 | 426 |
AATF,RAF1,SMARCA4,MAPK14,UBTF,PPP2CA,RB1,MDM2,CCNA2,BRD2,E2F4,TFDP1,CDKN1B,RBBP4,ATF2,CDK2,DNMT1,CBX4 |
| 1.319e-02 | -4.33 | N6-methyladenosine-containing RNA binding | molecular function | GO:1990247 | 7 | 4 | 17224 | 2647 |
HNRNPA2B1,YTHDF3,YTHDC1,YTHDC2 |
| 1.319e-02 | -4.33 | calcium-dependent protein serine/threonine phosphatase activity | molecular function | GO:0004723 | 7 | 4 | 17224 | 2647 |
PPP3CA,PPP3CB,CAMK2G,PPP3R1 |
| 1.319e-02 | -4.33 | antibiotic transmembrane transporter activity | molecular function | GO:0042895 | 7 | 4 | 17224 | 2647 |
SFXN5,MFSD10,SLC25A1,SLC26A6 |
| 1.319e-02 | -4.33 | TIMM23 (translocase of inner mitochondrial membrane 23) | protein interactions | 100287932 | 21 | 8 | 17029 | 2761 |
ATXN3,TMEM184B,PML,MCM2,PIKFYVE,RUFY1,GLMP,FANCI |
| 1.319e-02 | -4.33 | ARSG (arylsulfatase G) | protein interactions | 22901 | 21 | 8 | 17029 | 2761 |
QRSL1,SUMF1,FBXO21,IDE,TOR3A,PTPRK,MIA2,SRPK2 |
| 1.319e-02 | -4.33 | Nup188 (nucleoporin 188) | protein interactions | 227699 | 21 | 8 | 17029 | 2761 |
NUP188,RAE1,OGT,RPS24,NUSAP1,NUP62,SDF2L1,PKM |
| 1.319e-02 | -4.33 | WDR24 (WD repeat domain 24) | protein interactions | 84219 | 21 | 8 | 17029 | 2761 |
RRAGC,FGFR1OP,MIOS,RAE1,WDR59,SEH1L,FAF1,SRPK2 |
| 1.319e-02 | -4.33 | CCDC69 (coiled-coil domain containing 69) | protein interactions | 26112 | 21 | 8 | 17029 | 2761 |
FAM192A,NUDT8,MTA2,RMI2,TOP3A,GGPS1,SMURF1,RMI1 |
| 1.319e-02 | -4.33 | HSF4 (heat shock transcription factor 4) | protein interactions | 3299 | 21 | 8 | 17029 | 2761 |
SMARCA4,FKBP5,TIMM13,MAPK1,MAPK14,SESTD1,CDK2AP2,MAPK3 |
| 1.319e-02 | -4.33 | RASSF3 (Ras association domain family member 3) | protein interactions | 283349 | 21 | 8 | 17029 | 2761 |
MOB4,SIKE1,MDM2,STRIP1,APP,FGFR1OP2,STRN4,CDC37 |
| 1.319e-02 | -4.33 | SLC22A6 (solute carrier family 22 member 6) | protein interactions | 9356 | 21 | 8 | 17029 | 2761 |
MTX3,SLC38A7,ERGIC3,SLC26A2,CHPT1,APP,SFXN5,PDXDC1 |
| 1.319e-02 | -4.33 | HIST1H2BD (histone cluster 1 H2B family member d) | protein interactions | 3017 | 21 | 8 | 17029 | 2761 |
COX15,MCM5,PPM1G,H2AFX,MCM2,VDAC1,CD81,SDHA |
| 1.319e-02 | -4.33 | Nup155 (nucleoporin 155) | protein interactions | 170762 | 21 | 8 | 17029 | 2761 |
RANGAP1,NUP155,NDC1,TOMM20,CD3EAP,NUP205,SEH1L,NUP107 |
| 1.319e-02 | -4.33 | CD8A (CD8a molecule) | protein interactions | 925 | 21 | 8 | 17029 | 2761 |
LNX2,SREK1,CD59,HLA-B,COPA,HLA-E,HLA-A,SRSF1 |
| 1.319e-02 | -4.33 | LRRC8B (leucine rich repeat containing 8 VRAC subunit B) | protein interactions | 23507 | 21 | 8 | 17029 | 2761 |
LRRC8D,SLC44A1,LMBR1,CUL3,LRRC8A,PDE3B,CHPT1,TMEM179B |
| 1.319e-02 | -4.33 | NDUFA6 (NADH:ubiquinone oxidoreductase subunit A6) | protein interactions | 4700 | 21 | 8 | 17029 | 2761 |
SDHB,NDUFB9,NDUFA4,NDUFV2,NDUFS5,ATP5MF,NDUFA11,TBPL1 |
| 1.322e-02 | -4.33 | HOSHIDA_LIVER_CANCER_SUBCLASS_S1 | MSigDB lists | HOSHIDA_LIVER_CANCER_SUBCLASS_S1 | 232 | 48 | 17377 | 2626 |
TRIP10,SRGN,DCTN2,SLC2A1,ASAH1,KLC1,ATP6V1B2,LYN,FBRS,GNS,RPA2,ATP6V0B,PSMD2,CTSS,RALB,DPYSL2,DUT,ARF5,PPP4R1,CAPZA1,SRI,DNM2,ANXA5,CDC25B,CORO1A,GNAI2,LDHB,CYFIP1,RHOA,TIMP2,SLBP,ARHGDIB,RIT1,PKMYT1,CBFB,PLD3,SMAD2,MTHFD2,MFAP1,STK38,ADAM9,PKD2,TRAF5,HEXA,AP2S1,OAZ1,IFI16,SMARCD1 |
| 1.322e-02 | -4.33 | GSE21927_C26GM_VS_4T1_TUMOR_MONOCYTE_BALBC_UP | MSigDB lists | GSE21927_C26GM_VS_4T1_TUMOR_MONOCYTE_BALBC_UP | 176 | 38 | 17377 | 2626 |
PNISR,GNPDA1,FLOT1,USP48,ATPAF1,XPR1,FERMT3,RTKN,NUDT19,NT5DC1,MBD2,POP7,MDFIC,GNAI2,ZDHHC18,MLEC,CSRP1,RNASEH2C,CREG1,DENND1B,ANKRD33B,PBK,MAP4K4,NUSAP1,CHMP2B,KLF6,HAUS8,FAS,ACYP1,STK38,ODF2,KPNA2,DVL1,ZMIZ1,ZMAT3,LRP8,PDCD4,NIPA1 |
| 1.322e-02 | -4.33 | GSE2585_THYMIC_MACROPHAGE_VS_MTEC_UP | MSigDB lists | GSE2585_THYMIC_MACROPHAGE_VS_MTEC_UP | 176 | 38 | 17377 | 2626 |
SART1,CORO7,FOXM1,CDCA8,MYO9B,EPHX2,MAPK14,ABHD14A,WRNIP1,CD59,APLP2,NFATC3,CTSS,NUP210,PPCDC,KIF22,CDC25B,FAM171A1,IMPA2,GPX4,SPTAN1,POLR2L,GUK1,PBXIP1,MYBL2,ATP6V0A1,MIER2,COMMD4,TPD52L2,PFDN5,DSN1,PRMT7,IGBP1,YWHAH,MAPK1,DEF6,CDKN2A,HIGD2A |
| 1.322e-02 | -4.33 | GSE18804_SPLEEN_MACROPHAGE_VS_TUMORAL_MACROPHAGE_DN | MSigDB lists | GSE18804_SPLEEN_MACROPHAGE_VS_TUMORAL_MACROPHAGE_DN | 176 | 38 | 17377 | 2626 |
TMEM106C,USP7,RMI2,MON1B,DUSP22,FAM8A1,MYEF2,POLR3K,HDDC2,CLUAP1,SIAH1,TIMM23,NT5DC1,ANKRD13C,TMEM14C,EBAG9,NIPSNAP1,USO1,ZMYND11,NQO2,RDH10,RPL8,HSDL1,ASB13,VKORC1,HAGH,EIF3H,ANKRD46,PON2,WAS,RPL32,ZNF700,MLYCD,ADAM9,ZFP90,ATMIN,NUDT3,DYNC1LI2 |
| 1.322e-02 | -4.33 | GSE27291_6H_VS_7D_STIM_GAMMADELTA_TCELL_UP | MSigDB lists | GSE27291_6H_VS_7D_STIM_GAMMADELTA_TCELL_UP | 176 | 38 | 17377 | 2626 |
UBE2D3,ANKRD27,PDCD6IP,KIAA0100,MRPL42,HMGXB3,ZNF267,GGA2,HCFC1R1,GLRX3,MRPL19,NDUFS7,ZNF92,SYNM,NOC2L,TAGLN2,MVP,TMX1,MOB4,RHOA,RFXANK,TBRG4,EMP3,ARHGDIB,SRSF5,EIF4H,RFC2,NMT2,RHOB,PRIM1,SDHB,SLC19A1,VPS26B,LSM6,UQCRH,DVL1,COPS6,IPO4 |
| 1.322e-02 | -4.33 | ABC-family proteins mediated transport | REACTOME pathways | R-HSA-382556 | 107 | 27 | 10287 | 1696 |
ABCA3,PSMA8,ERLIN1,ABCC10,PSMB7,PSMA1,ABCB10,PSMD9,PSMB9,ABCF1,PSMB3,PSMC4,DERL1,PSMD2,PSMD1,PSMA6,EIF2S2,RPS27A,PSMD8,PSMD3,SEL1L,ABCD1,RNASEL,PSMC1,RNF5,ABCC1,ABCC5 |
| 1.324e-02 | -4.32 | GO_REGULATION_OF_DNA_REPLICATION | MSigDB lists | GO_REGULATION_OF_DNA_REPLICATION | 154 | 34 | 17377 | 2626 |
CHTF18,CDT1,RAC1,BLM,TTF1,WRNIP1,PCNA,SMC3,SHC1,CDC42,NVL,TERF2,TGFB1,CCT2,RFC3,NEK7,GTPBP4,CDC6,AURKB,MEN1,RFC2,CCT8,MAPK3,STOML2,PPP2CA,MAP3K4,PML,CHEK2,ZNF830,MAPK1,CDK2,POT1,HRAS,TERF1 |
| 1.324e-02 | -4.32 | GO_NUCLEOSIDE_PHOSPHATE_BIOSYNTHETIC_PROCESS | MSigDB lists | GO_NUCLEOSIDE_PHOSPHATE_BIOSYNTHETIC_PROCESS | 154 | 34 | 17377 | 2626 |
NADSYN1,KARS,PPCS,SUCLG1,UCK2,RRM1,UCK1,SLC35B2,FLAD1,ERH,GART,DUT,ATIC,ADCY9,PPCDC,UPRT,ATP6V0A2,SLC26A2,ADCY7,AMPD2,TGFB1,TK1,GUK1,ADSL,RRM2,ATP6V0A1,DCTD,PRPSAP1,STOML2,ADSS,DCK,PRPS2,TBPL1,IMPDH1 |
| 1.325e-02 | -4.32 | THOC5 (THO complex 5) | protein interactions | 8563 | 65 | 18 | 17029 | 2761 |
FYTTD1,SARNP,THOC1,DDX24,MRPL12,RPL6,CSNK2A1,BCLAF1,RPL27A,DDX39A,DDX23,GTF2F1,EIF4A3,KLF16,MRPS27,CHTOP,ZNF830,SMAD4 |
| 1.325e-02 | -4.32 | PIH1D1 (PIH1 domain containing 1) | protein interactions | 55011 | 65 | 18 | 17029 | 2761 |
RPAP3,TELO2,NPHP4,DCAF6,POLR2I,POLR2G,POLR2L,POLR2D,SEC16A,POLR3K,POLR2A,TSC1,POLR2J,PDRG1,MAPK6,RUVBL2,ECD,FBL |
| 1.325e-02 | -4.32 | MIB1 (mindbomb E3 ubiquitin protein ligase 1) | protein interactions | 57534 | 65 | 18 | 17029 | 2761 |
UBE2D3,FGFR1OP,ZBTB10,MAPRE1,DYNLL1,TOP3A,RANGAP1,AZI2,BLM,PCM1,CDC27,CCDC14,CENPJ,DAPK1,GEMIN4,RBBP4,DDB1,POC5 |
| 1.325e-02 | -4.32 | ZMYM2 (zinc finger MYM-type containing 2) | protein interactions | 7750 | 65 | 18 | 17029 | 2761 |
ZNF202,DYNLL1,SUMO2,RCOR1,CTCF,NFATC2,UBE2I,UBTF,HNRNPA2B1,HSPA4,RAD18,HNRNPH3,PML,ARRDC1,FUS,CREB1,SMAD4,HDAC2 |
| 1.325e-02 | -4.32 | ASH2L (ASH2 like, histone lysine methyltransferase complex subunit) | protein interactions | 9070 | 65 | 18 | 17029 | 2761 |
KMT2E,CXXC1,WDR82,BRCA1,MEF2D,KMT2C,MEN1,WDR5,PAGR1,CDC73,USF1,E2F4,ZNF335,E2F1,MICU2,KMT2B,CCDC69,SMURF1 |
| 1.325e-02 | -4.32 | USP10 (ubiquitin specific peptidase 10) | protein interactions | 9100 | 65 | 18 | 17029 | 2761 |
CYLD,KMT2E,PRKAA1,USP10,GAR1,ANKRD28,PCNA,MDM2,PTEN,TANK,MSH2,YBX1,TARDBP,PPP6R3,PPP6R2,PABPC1,PPP6R1,CDC5L |
| 1.325e-02 | -4.32 | THAP11 (THAP domain containing 11) | protein interactions | 57215 | 65 | 18 | 17029 | 2761 |
SRSF11,CCDC93,MAX,RPRD1A,TPX2,RCOR1,PSMD9,HMG20A,GIT2,OIP5,GRIPAP1,ABRAXAS2,RABGAP1L,ARNTL,OGT,CDK2,MCPH1,TSPAN5 |
| 1.325e-02 | -4.32 | FXR1 (FMR1 autosomal homolog 1) | protein interactions | 8087 | 65 | 18 | 17029 | 2761 |
CCDC93,CYFIP1,THOC1,ZNF512,SUZ12,CUL3,CSNK2A1,BCLAF1,FXR1,CCNB1,CYFIP2,LUC7L,CAND1,CCNA2,WDR76,CLU,IFI16,LUC7L2 |
| 1.327e-02 | -4.32 | GSE25677_MPL_VS_R848_STIM_BCELL_DN | MSigDB lists | GSE25677_MPL_VS_R848_STIM_BCELL_DN | 165 | 36 | 17377 | 2626 |
WASF2,CYTIP,IER2,GMFG,ADD1,CERK,MYH9,DOCK11,IL21R,C1GALT1,RAB8A,ADD3,CDC25B,CNN2,FAM76B,PLCL2,GNAI2,DNMT1,MTPN,CSNK1G3,PPP3CA,SNX2,DNAJC9,ATP6V0A1,KLF6,PICALM,ISG15,SOCS7,PRIM1,SH3BP5,JAK1,BRWD1,CSK,NRM,EHD4,ABCA1 |
| 1.327e-02 | -4.32 | GSE25677_MPL_VS_R848_STIM_BCELL_UP | MSigDB lists | GSE25677_MPL_VS_R848_STIM_BCELL_UP | 165 | 36 | 17377 | 2626 |
UBE2E2,GOLIM4,PLXNC1,CREBL2,HMGN3,COPG2,BZW2,PIP4K2A,GNS,HERC3,ZKSCAN1,RRBP1,BCAP29,GM2A,MICAL3,DRAM2,PDLIM2,CARS2,CYFIP1,PTPN18,PRKDC,ATXN1,FBXO9,ARHGEF12,DCLRE1C,RPS9,ABHD5,RBM47,WDR11,ACBD4,TRIM32,PSAP,RUFY3,CD81,PDCD4,TMEM131 |
| 1.331e-02 | -4.32 | regulation of viral life cycle | biological process | GO:1903900 | 137 | 31 | 17256 | 2622 |
PPIB,STAU1,CHMP2A,TRIM8,TRIM11,YTHDC2,PPIE,ILF3,EIF2AK4,CHMP2B,TRIM28,ISG15,RAD23A,CCNK,TRIM26,SMC3,BANF1,PML,BCL2,CHMP4B,DDX5,RNASEL,TRIM32,VPS4A,MAVS,PARP10,PABPC1,IFI16,ZC3HAV1,DDB1,SRPK2 |
| 1.334e-02 | -4.32 | ZnF_UBP | smart domains | SM00290 | 11 | 5 | 9493 | 1367 |
BRAP,USP39,USP20,USP5,USP13 |
| 1.335e-02 | -4.32 | CRGAARNNNNCGA_UNKNOWN | MSigDB lists | CRGAARNNNNCGA_UNKNOWN | 45 | 13 | 17377 | 2626 |
TMUB1,NDUFS1,CDC27,MTA2,PIK3R2,ARGLU1,CREB1,EIF1B,PICALM,UBE2M,SPTAN1,PRPF19,C14orf119 |
| 1.335e-02 | -4.32 | PID_TNF_PATHWAY | MSigDB lists | PID_TNF_PATHWAY | 45 | 13 | 17377 | 2626 |
ADAM17,CYLD,TXN,TNFAIP3,BIRC3,TAB2,MAP4K4,STAT1,RFFL,MAP4K3,MAP3K5,BIRC2,FADD |
| 1.335e-02 | -4.32 | MARIADASON_RESPONSE_TO_BUTYRATE_SULINDAC_6 | MSigDB lists | MARIADASON_RESPONSE_TO_BUTYRATE_SULINDAC_6 | 45 | 13 | 17377 | 2626 |
NAP1L1,PCNA,ETS2,CCDC14,SESTD1,DHX9,TIA1,ANP32A,HMGB2,TOP2B,SMC2,APOOL,ARID1B |
| 1.335e-02 | -4.32 | ROESSLER_LIVER_CANCER_METASTASIS_DN | MSigDB lists | ROESSLER_LIVER_CANCER_METASTASIS_DN | 45 | 13 | 17377 | 2626 |
MOAP1,GALK1,CDCA4,PDLIM1,IVNS1ABP,TACC1,TRMU,LRPPRC,DNAJC9,SUPT7L,PDCD11,MGAT5,SH3GLB1 |
| 1.335e-02 | -4.32 | FOSTER_TOLERANT_MACROPHAGE_DN | MSigDB lists | FOSTER_TOLERANT_MACROPHAGE_DN | 388 | 75 | 17377 | 2626 |
FAM208B,FEZ2,LUZP1,AGRN,TRIP10,PPP1R15B,FAM129A,C5orf30,SNN,CMTM6,CHD1,KTN1,MXD1,PHC2,NEK6,ETV6,SLC44A1,SEPT11,MINPP1,TIPARP,F2R,ZNF800,EZR,PFKFB3,TOR1AIP2,SLC25A22,TANC1,ASB13,ODC1,RHBDF2,PLEKHF2,SOCS7,HHEX,RBL1,TAB2,MAFK,WDR59,PRPF4,FKBP5,LRCH1,DDX58,B4GALT5,GADD45G,ARID5A,MED13L,HMGN3,ZNRF3,LMNA,HOMER1,ITGB8,CENPJ,TPST1,DCP1A,AFF1,CITED2,STAT3,PPA1,ETV3,TNFAIP3,DENND1B,USP42,RFFL,ARMC8,HSPA1B,FAS,TRIM26,NFIL3,NLRC5,PML,VCPIP1,TMEM219,SLC16A1,SRSF3,PDLIM5,IFI16 |
| 1.335e-02 | -4.32 | RCOR1 (REST corepressor 1) | protein interactions | 23186 | 89 | 23 | 17029 | 2761 |
CCDC93,MAX,RPRD1A,MECP2,TCF3,SUMO2,RCOR1,SMARCA4,NFATC2,NUF2,PSMD9,GIT2,HMG20A,OIP5,SUB1,HSPA4,GRIPAP1,RABGAP1L,ARNTL,UHRF2,ARRDC1,SMARCE1,HDAC2 |
| 1.337e-02 | -4.31 | central_nervous_system-brain-glioma-oligoastrocytoma_Grade_III | COSMIC cancer mutations | central_nervous_system-brain-glioma-oligoastrocytoma_Grade_III | 118 | 27 | 17385 | 2587 |
POLA2,CLPTM1,ASH1L,NRAS,CSRP1,VHL,CIC,SF3B1,MRPL39,PPP1R21,MON1B,KRAS,KDM1B,GNAS,CDKN2C,FGFR3,PTEN,ZKSCAN1,NLRC5,ATP6V0A2,ZMIZ1,H3F3A,ZBTB11,ABCA1,HRAS,CDKN2A,FUBP1 |
| 1.341e-02 | -4.31 | GO_NUCLEAR_TRANSCRIPTION_FACTOR_COMPLEX | MSigDB lists | GO_NUCLEAR_TRANSCRIPTION_FACTOR_COMPLEX | 127 | 29 | 17377 | 2626 |
TCF12,GTF3C6,ERCC1,HNRNPAB,KAT2A,TCF3,NFATC2,EDF1,SOX4,PRMT2,SNAPC4,TRIM28,GTF2F1,TAF2,RB1,SMAD2,MED10,CD3EAP,HIPK2,E2F1,TBPL1,TAF5L,TAF12,CREB1,GTF2H2,TAF6,STAT3,SMAD4,CARM1 |
| 1.341e-02 | -4.31 | GO_NEGATIVE_REGULATION_OF_BINDING | MSigDB lists | GO_NEGATIVE_REGULATION_OF_BINDING | 127 | 29 | 17377 | 2626 |
CPNE1,PPP3CA,MAPRE1,BTAF1,HABP4,GTPBP4,AURKB,ADRB2,PARK7,MAD2L2,MAPK3,PTPRF,TFAP4,SP100,GOLGA2,EIF4A3,RALB,PIN1,E2F1,SRI,GTSE1,ZFP90,RUVBL2,DVL1,ROCK1,ARRB2,IFI16,CARM1,HDAC2 |
| 1.341e-02 | -4.31 | MULLIGHAN_NPM1_MUTATED_SIGNATURE_2_UP | MSigDB lists | MULLIGHAN_NPM1_MUTATED_SIGNATURE_2_UP | 127 | 29 | 17377 | 2626 |
PDPK1,PRKAB1,ACP2,HMGN5,CLSPN,ZNF768,NEK7,TLK1,C5orf30,B4GALT4,COMMD4,PAIP1,RHEB,DST,MAN2A2,CAT,KPNA4,TBC1D17,DCK,HNRNPH3,TANK,PDS5B,TFDP2,ZNF770,MTX2,SMC4,CSTF1,SRPK2,RYBP |
| 1.341e-02 | -4.31 | acetylation-dependent protein binding | molecular function | GO:0140033 | 18 | 7 | 17224 | 2647 |
SMARCA4,BRD7,BRD4,BRD2,BAZ2A,BRD9,CARM1 |
| 1.341e-02 | -4.31 | H4 histone acetyltransferase activity | molecular function | GO:0010485 | 18 | 7 | 17224 | 2647 |
KANSL2,USP22,WDR5,KAT2A,NAA60,NAA50,OGT |
| 1.341e-02 | -4.31 | lysine-acetylated histone binding | molecular function | GO:0070577 | 18 | 7 | 17224 | 2647 |
SMARCA4,BRD7,BRD4,BRD2,BAZ2A,BRD9,CARM1 |
| 1.342e-02 | -4.31 | Cyclin-like | interpro domains | IPR013763 | 36 | 11 | 18492 | 2768 |
CCNC,CCNK,RB1,CCNA2,RBL1,CCNL2,CABLES2,CCNB1,CCNF,CCNB2,CABLES1 |
| 1.343e-02 | -4.31 | ATP hydrolysis coupled ion transmembrane transport | biological process | GO:0099131 | 31 | 10 | 17256 | 2622 |
ATP6V0B,ATP1A1,ATP5MC3,ATP6V0A2,ATP6V0A1,ATP6V0C,ATP6V1C1,ATP6V1B2,ATP6V0E1,ATP6V0D1 |
| 1.343e-02 | -4.31 | placenta blood vessel development | biological process | GO:0060674 | 31 | 10 | 17256 | 2622 |
GGNBP2,ITGB8,NSDHL,PKD2,ARID1A,RBPJ,NR2F2,RBM15,MAPK1,TMED2 |
| 1.347e-02 | -4.31 | PHONG_TNF_RESPONSE_NOT_VIA_P38 | MSigDB lists | PHONG_TNF_RESPONSE_NOT_VIA_P38 | 324 | 64 | 17377 | 2626 |
IER2,ZBTB10,CYLD,TRIP10,IVNS1ABP,FAM129A,MYH9,TGOLN2,PLXNA1,ZNF267,SLC25A37,SP100,TNFAIP8,PPME1,IL6ST,DDA1,CDKN1B,MYBL1,KCNAB2,HTRA2,ANKLE2,PPIF,RHOBTB3,BIRC3,SLC25A22,CADM1,SOX4,OGFR,PSMB9,RHBDF2,OPTN,NECAP2,DNAJC10,RBM47,JAK1,SEL1L,SMAD1,ABCA1,PARP12,B4GALT5,TRIO,SRGN,FLOT1,DNAJB1,ETS1,WDR48,HLA-A,CFLAR,TANK,TPCN1,CSNK1G2,NET1,KLF6,BSDC1,INF2,SLCO4A1,HLA-B,SERTAD2,ETS2,TFE3,MEGF9,NUP62,NR2F2,PDLIM5 |
| 1.351e-02 | -4.30 | positive regulation of protein complex assembly | biological process | GO:0031334 | 248 | 51 | 17256 | 2622 |
RHOG,MAPRE1,RHOC,MECP2,CDT1,CHD1L,RAC1,ACTR3,NCKAP1,RGS2,JMY,RPA2,SUB1,VASP,ARPC5,XPA,CDKN1B,FNIP2,CNOT6L,CREB1,GTF2H2,SPIDR,CARMIL1,DCTN1,MLST8,TGFB1,CYFIP1,ERCC1,PSRC1,RHOA,RBX1,NCK1,WIPF1,BCLAF1,ARPC1A,SH3GLB1,CAND1,RPA1,PSMC4,HSPA1B,IDE,WAS,CNOT6,PIEZO1,CLU,SLF1,PSMC1,SLF2,TERF1,DDB1,FAF1 |
| 1.356e-02 | -4.30 | CDKN1B (cyclin dependent kinase inhibitor 1B) | protein interactions | 1027 | 94 | 24 | 17029 | 2761 |
RHOA,TSC2,RBX1,VHL,RPS6KA1,CUL1,DCLRE1C,UBE2I,CCNB1,STMN1,LYN,FOXO3,CDK5,TSC1,KPNA4,KPNA1,CCNA2,PIN1,YWHAZ,KPNA2,COPS6,CDK2,YWHAH,DDB1 |
| 1.357e-02 | -4.30 | receptor metabolic process | biological process | GO:0043112 | 100 | 24 | 17256 | 2622 |
SNX25,TGFB1,RAB11B,EZR,ZNRF3,BECN1,SCYL2,PICALM,SH3GLB1,TFRC,CDK5,FNTA,GRK2,FUT8,ITGB1,DNM2,AP2B1,CD81,SMURF1,ARRB2,GTF2H2,AP2S1,ALS2,CAPN1 |
| 1.357e-02 | -4.30 | RNA-helicase_DEAD-box_CS | interpro domains | IPR000629 | 27 | 9 | 18492 | 2768 |
DDX47,DDX24,EIF4A3,DDX20,DDX31,DDX5,DDX42,DDX17,DDX23 |
| 1.357e-02 | -4.30 | Mit_carrier | interpro domains | IPR002067 | 27 | 9 | 18492 | 2768 |
SLC25A19,SLC25A12,SLC25A22,SLC25A44,SLC25A43,SLC25A5,SLC25A39,SLC25A36,SLC25A1 |
| 1.360e-02 | -4.30 | GSE17721_12H_VS_24H_LPS_BMDC_UP | MSigDB lists | GSE17721_12H_VS_24H_LPS_BMDC_UP | 193 | 41 | 17377 | 2626 |
CHMP2A,UBE2E2,FEZ2,PARP12,TOR3A,PCSK7,IL21R,RAB11A,WRNIP1,EEF2K,CAPN2,IRF4,APLP2,HDAC7,ARHGEF2,MDFIC,SMC4,MORC3,PPAN,MAPRE2,BIRC3,KLF10,NEK7,WDR1,OAF,RFFL,PLEC,ARID1A,KLF6,ISG15,MKNK1,CLK3,PSMD8,SIAH2,RBMS1,CHMP4B,EHD4,IGBP1,PDLIM5,YWHAH,RNF114 |
| 1.360e-02 | -4.30 | GSE40274_LEF1_VS_FOXP3_AND_LEF1_TRANSDUCED_ACTIVATED_CD4_TCELL_UP | MSigDB lists | GSE40274_LEF1_VS_FOXP3_AND_LEF1_TRANSDUCED_ACTIVATED_CD4_TCELL_UP | 193 | 41 | 17377 | 2626 |
RMND5A,SMAP1,H2AFZ,GNPDA1,CERK,CREBL2,AGFG1,BCL2L1,IKBIP,MXD1,SSR1,EEF2K,CDKN2C,HOMER1,TBC1D14,JAZF1,LPIN2,ZNF260,TPST1,CDC25B,CYFIP1,ADAM17,NEK7,LRBA,MIER1,LNX2,SLBP,CYB5A,MYO1F,ADSS,PTPRF,ZNF862,FNTA,TWSG1,HIPK2,GADD45B,OAZ2,ANP32E,ST3GAL2,CD81,SNX14 |
| 1.360e-02 | -4.30 | GSE29949_CD8_POS_DC_SPLEEN_VS_MONOCYTE_BONE_MARROW_DN | MSigDB lists | GSE29949_CD8_POS_DC_SPLEEN_VS_MONOCYTE_BONE_MARROW_DN | 193 | 41 | 17377 | 2626 |
RMND5A,PPP1R12A,DHPS,NACA,PRKAA1,FLOT1,COX4I1,PMF1,AP3S1,MAP1LC3B,CREM,PRNP,PHC2,EIF2S2,SP100,RPL19,OSTF1,TP53BP2,APOOL,CITED2,RYBP,CPNE1,FTL,PRKAR1B,ELP4,RRM2,BICD2,ELK1,RPL27A,EIF4H,KLF6,GFER,CCT8,SERTAD2,DTX4,DCAF11,CEBPG,FKBP5,ANP32E,ANXA11,BYSL |
| 1.361e-02 | -4.30 | Validated targets of C-MYC transcriptional activation | Pathway Interaction DB | myc_activpathway | 81 | 24 | 2226 | 426 |
TK1,MAX,KAT2A,NDUFAF2,SLC2A1,LDHA,E2F3,RIOX2,CCNB1,SUPT7L,ODC1,TFRC,RPL11,UBTF,COMMD3-BMI1,HSPA4,PDCD10,BIRC5,PRDX3,HUWE1,MTA1,TAF12,RUVBL2,SMAD4 |
| 1.361e-02 | -4.30 | TCP1 (t-complex 1) | protein interactions | 6950 | 196 | 44 | 17029 | 2761 |
UNK,CYLD,COPA,POC1A,WDTC1,GNB2,CDC73,SSR1,CDK5,RFWD3,RPN1,HUWE1,ZNF746,ATF2,NIPSNAP1,CDC5L,MOB4,CCT2,STAU1,DCAF8,VHL,GBA,CUL3,WDR82,NFATC2,BRCA1,CBFA2T2,MCM2,CCT8,RPSA,PPP2CA,DERL1,EPRS,HSPA4,DCAF11,ACTB,XRCC3,PRPF4,FUS,CDK2,IGBP1,SMURF1,PPP2R2D,DCAF5 |
| 1.362e-02 | -4.30 | response to hypoxia | biological process | GO:0001666 | 334 | 66 | 17256 | 2622 |
DNMT3A,NF1,RAF1,ALKBH5,SLC29A1,SIRT2,CCNB1,BECN1,BIRC2,USF1,CCNA2,PSMA6,MDM2,PSMD1,CDKN1B,PLK3,RBX1,PSMA8,VHL,PSMB7,PSMB9,SCAP,RPS27A,PSMD8,PSMD3,HIPK2,PSMC1,SMAD4,UBE2D3,TM9SF4,AGTRAP,PHB2,MECP2,PRKAA1,PSMD9,ETS1,FOXO3,LMNA,CFLAR,CAPN2,PSMD2,TIGAR,SUV39H2,PTEN,AHCY,BCL2,CREB1,CITED2,HP1BP3,TGFB1,ADAM17,RHOA,ERO1A,LDHA,ADSL,PSMA1,PKM,PSMB3,PSMC4,CAT,PDLIM1,PML,E2F1,RBPJ,CPEB2,EGLN1 |
| 1.365e-02 | -4.29 | intrinsic component of organelle membrane | cellular component | GO:0031300 | 191 | 40 | 18223 | 2701 |
IMMT,TOMM20,SYS1,RAB11B,SLC39A13,PCSK7,ABCB10,PXMP2,SLC35B1,SLC35B2,SLC25A44,QSOX2,ANKLE1,TIMM23,RAB35,SLC35B4,TPST1,YIF1B,ABCD1,APOOL,VOPP1,BAK1,COA3,MFNG,TOMM40,RHOT1,RAB5B,RHOT2,CHCHD6,TMEM201,MPC1,MFN2,YIF1A,LEMD2,CHCHD3,GALNT2,GOLGA7,TIMM17A,SLC25A19,SAMD8 |
| 1.370e-02 | -4.29 | MED23 (mediator complex subunit 23) | protein interactions | 9439 | 170 | 39 | 17029 | 2761 |
CCNC,CTDP1,KARS,PPP1R12A,WDTC1,MED13L,CYCS,TAF6L,SEC16A,NCAPG,ETS1,SSR1,FBRS,RB1,PDXP,MED8,MED10,HADHB,TRA2B,TCEA1,RBM15,PHKG2,NCOA2,MED22,ATP5IF1,PPP1R9B,SEC61B,VDAC2,RCOR1,SUPT20H,POLR2A,MBIP,CORO1C,MED15,PGRMC1,VCPIP1,ROCK1,SNRPG,RBPJ |
| 1.370e-02 | -4.29 | HTR3A (5-hydroxytryptamine receptor 3A) | protein interactions | 3359 | 99 | 25 | 17029 | 2761 |
CLPTM1,GLT8D1,ABCA3,ERMP1,ATG9A,TMEM39A,TMX4,ATP6V0A1,LRRC8A,SLC29A1,SYVN1,SPPL2B,ABHD14A,EBP,LEMD2,LRRC8D,FUT8,PIGG,LMBR1,TAP2,DHFR2,TTC17,SGCB,SLC12A2,APOL2 |
| 1.374e-02 | -4.29 | ITIH5 (inter-alpha-trypsin inhibitor heavy chain family member 5) | protein interactions | 80760 | 10 | 5 | 17029 | 2761 |
XRCC3,BRCA1,CHEK2,NOTCH2,RB1CC1 |
| 1.374e-02 | -4.29 | Csde1 (cold shock domain containing E1, RNA binding) | protein interactions | 229663 | 10 | 5 | 17029 | 2761 |
DUSP11,EIF4H,STRAP,TMEM131,ABHD16A |
| 1.374e-02 | -4.29 | Rab11a (RAB11A, member RAS oncogene family) | protein interactions | 53869 | 10 | 5 | 17029 | 2761 |
CHEK2,SLC25A5,RAB11B,WDR44,PHB2 |
| 1.374e-02 | -4.29 | MTERF4 (mitochondrial transcription termination factor 4) | protein interactions | 130916 | 10 | 5 | 17029 | 2761 |
ATXN1,MND1,APP,KBTBD7,MRPL12 |
| 1.374e-02 | -4.29 | CDKN2AIPNL (CDKN2A interacting protein N-terminal like) | protein interactions | 91368 | 10 | 5 | 17029 | 2761 |
BCLAF1,RBM3,PSRC1,TAF12,SEC16A |
| 1.374e-02 | -4.29 | RGCC (regulator of cell cycle) | protein interactions | 28984 | 10 | 5 | 17029 | 2761 |
PLK1,KRAS,SMAD2,TRAF7,CARS2 |
| 1.374e-02 | -4.29 | RPL13P12 (ribosomal protein L13 pseudogene 12) | protein interactions | 388344 | 10 | 5 | 17029 | 2761 |
CUL1,RPA2,RPA1,CAND1,CUL3 |
| 1.374e-02 | -4.29 | L3mbtl2 (L3MBTL2 polycomb repressive complex 1 subunit) | protein interactions | 214669 | 10 | 5 | 17029 | 2761 |
WDR5,TTF1,TFDP1,HDAC2,PCGF6 |
| 1.374e-02 | -4.29 | RGS13 (regulator of G protein signaling 13) | protein interactions | 6003 | 10 | 5 | 17029 | 2761 |
LIN9,CREB1,GNAI2,PRKACA,SRRT |
| 1.374e-02 | -4.29 | Samhd1 (SAM domain and HD domain, 1) | protein interactions | 56045 | 10 | 5 | 17029 | 2761 |
CCNA2,CHTOP,CCNB1,CDK2,MRPS27 |
| 1.374e-02 | -4.29 | NUDT14 (nudix hydrolase 14) | protein interactions | 256281 | 10 | 5 | 17029 | 2761 |
TERF2IP,ZCCHC10,WDYHV1,TERF1,RAF1 |
| 1.374e-02 | -4.29 | YIF1B (Yip1 interacting factor homolog B, membrane trafficking protein) | protein interactions | 90522 | 10 | 5 | 17029 | 2761 |
DERL1,ESYT1,ATP6V1B2,ICAM2,MYO18A |
| 1.374e-02 | -4.29 | RCN3 (reticulocalbin 3) | protein interactions | 57333 | 10 | 5 | 17029 | 2761 |
MKNK1,XRCC3,KLHL42,MBD3,STAT6 |
| 1.374e-02 | -4.29 | ARL6 (ADP ribosylation factor like GTPase 6) | protein interactions | 84100 | 10 | 5 | 17029 | 2761 |
TOR1AIP2,SART1,SEC61B,ARL6IP6,ARL6IP1 |
| 1.374e-02 | -4.29 | ARHGEF28 (Rho guanine nucleotide exchange factor 28) | protein interactions | 64283 | 10 | 5 | 17029 | 2761 |
GNA12,TARDBP,FUS,RHOA,YWHAH |
| 1.374e-02 | -4.29 | GAVIN_FOXP3_TARGETS_CLUSTER_T4 | MSigDB lists | GAVIN_FOXP3_TARGETS_CLUSTER_T4 | 85 | 21 | 17377 | 2626 |
CYFIP1,KARS,BTG2,FAM129A,SMU1,GLUD1,ARF1,ODC1,PSMB3,ADSS,SH3BP5,IRF4,AHNAK,ITGB8,HINT1,SNX18,PSMD8,ITGB1,AHCY,SNX14,GPX4 |
| 1.374e-02 | -4.29 | GO_NEGATIVE_REGULATION_OF_CYSTEINE_TYPE_ENDOPEPTIDASE_ACTIVITY | MSigDB lists | GO_NEGATIVE_REGULATION_OF_CYSTEINE_TYPE_ENDOPEPTIDASE_ACTIVITY | 85 | 21 | 17377 | 2626 |
BCL2L12,BIRC3,RPS6KA1,AKT2,RAF1,XIAP,CSNK2A1,RFFL,BIRC2,PARK7,MDM2,TNFAIP8,PRDX3,BIRC5,PRDX5,ARL6IP1,SIAH2,GPI,ARRB2,IGBP1,IFI16 |
| 1.374e-02 | -4.29 | positive regulation of I-kappaB kinase/NF-kappaB signaling | biological process | GO:0043123 | 170 | 37 | 17256 | 2622 |
MIB2,RHOC,GPR89A,SLC35B2,IRF3,UBE2I,SLC20A1,BIRC2,CFLAR,DDRGK1,TERF2IP,FKBP1A,C18orf32,NEK6,ZDHHC13,MAVS,TFG,MAP3K14,F2R,EEF1D,RHOA,BRD4,TRIM8,BIRC3,MIER1,ATP2C1,UBE2V1,FADD,TAB2,RPS27A,CANT1,NUP62,TICAM1,TMEM101,TRIM32,PPP5C,TRAF5 |
| 1.374e-02 | -4.29 | peptidyl-serine phosphorylation | biological process | GO:0018105 | 170 | 37 | 17256 | 2622 |
CLSPN,PRKAA1,CCNB1,CSNK1A1,PRKACA,MAPK14,CDK5,NEK6,GRK2,BCL2,MAST2,PHKG2,CAMK2G,CSNK1G3,MORC3,PDPK1,PLK1,CSNK1G2,MAPKAPK3,AKT2,PRKDC,AURKB,MAP2K2,DAPK3,MASTL,MAPK3,MKNK1,STK38,HIPK2,CSNK1G1,CAB39,STK11,CHEK2,CDK2,MAPK1,HIPK3,CSNK1D |
| 1.376e-02 | -4.29 | p38 MAPK signaling pathway | Pathway Interaction DB | p38_mkk3_6pathway | 29 | 11 | 2226 | 426 |
MAP3K4,CALM2,TXN,TAB2,CCM2,GADD45B,TAOK1,RAC1,GADD45G,MAP3K5,MAPK14 |
| 1.376e-02 | -4.29 | GSE17721_LPS_VS_GARDIQUIMOD_24H_BMDC_DN | MSigDB lists | GSE17721_LPS_VS_GARDIQUIMOD_24H_BMDC_DN | 182 | 39 | 17377 | 2626 |
SEPHS2,SRM,MRPS2,GORASP1,DHPS,RHOC,LAMTOR3,STARD7,TM9SF3,PSEN1,EEF2K,PSMA6,SMC3,ATP2A2,SSBP3,AKAP8,BANF1,ATP13A3,SLC44A1,LTN1,LPCAT1,NSDHL,PBK,PPP1R21,RCOR1,SMC2,SOX4,API5,STK17B,PICALM,MAT2A,TFEB,MKNK1,FNTA,SMAD2,STT3A,ADAM9,KPNA2,SLC25A39 |
| 1.376e-02 | -4.29 | GSE3982_CTRL_VS_LPS_1H_NEUTROPHIL_UP | MSigDB lists | GSE3982_CTRL_VS_LPS_1H_NEUTROPHIL_UP | 182 | 39 | 17377 | 2626 |
IER2,PPP1R12A,MRPS2,ZNF107,CBLL1,CUL1,KLF13,ASAH1,DNAJB1,ASXL2,MIS12,PRDM4,NAA50,PDS5B,SAP30L,ABI1,RNF5,ALDH9A1,FDFT1,PPP3CA,PPT1,TLK1,TUFM,GALNT7,SEPT7,CDC23,SRSF1,PTPRF,HLA-B,SLC19A1,RBM47,CCDC86,OSBPL8,TIMM17A,CEBPG,MEGF9,FAM208A,OAZ1,DDX42 |
| 1.376e-02 | -4.29 | GSE360_L_DONOVANI_VS_T_GONDII_MAC_UP | MSigDB lists | GSE360_L_DONOVANI_VS_T_GONDII_MAC_UP | 182 | 39 | 17377 | 2626 |
LZTR1,MPHOSPH8,TMEM184B,URB2,CDK2AP2,CHD1L,KIAA0232,TRIO,BCL2L1,FKBP2,RNF103,RRN3,NRF1,DAD1,AKAP8,BANF1,ANXA5,MOB1A,F2R,PPIF,PLK3,ACP2,RHOA,KLF10,ZNF202,PRPF3,GALK2,PDHX,GLOD4,SDHB,TRAM2,ALDH3B1,AHNAK,TTLL4,ACOX1,OAZ2,CAPN7,DTX4,LTA4H |
| 1.376e-02 | -4.29 | GSE21360_NAIVE_VS_TERTIARY_MEMORY_CD8_TCELL_UP | MSigDB lists | GSE21360_NAIVE_VS_TERTIARY_MEMORY_CD8_TCELL_UP | 182 | 39 | 17377 | 2626 |
EXOC3,ADD1,CENPF,PTTG1,CERK,NANS,MAP1LC3B,SPAG5,ANKRD28,GOT2,AKAP8,PPP6C,TPST1,AKR1B1,GTSE1,H2AFY,CNN2,GPX4,ACSL5,TIMP2,FAM172A,TACC1,CIC,SSR2,PKMYT1,ESYT1,UBE4B,ELK1,NDRG3,WAS,HSPB11,SERF2,ATXN2L,CABIN1,SPCS3,CCNB2,UBE2C,TRAF5,SMARCD1 |
| 1.376e-02 | -4.29 | GSE7852_THYMUS_VS_FAT_TCONV_UP | MSigDB lists | GSE7852_THYMUS_VS_FAT_TCONV_UP | 182 | 39 | 17377 | 2626 |
DNAJC5,DNMT3A,MTX3,C1orf112,TIA1,ARGLU1,GGA2,AP3S1,FAM8A1,CNOT3,C2orf68,ZER1,NAPG,MED8,TIMELESS,GEMIN6,CYB5R1,TMEM9,HDHD2,DRAM2,LDHB,PLK1,CELSR2,TIMMDC1,RAD51AP1,SLC26A6,ITM2A,GORAB,NUSAP1,THNSL1,RAB5B,PTPRF,PLD3,C1orf131,OGT,CNOT6,CHEK2,RNF14,CDK2 |
| 1.376e-02 | -4.29 | GSE5589_IL6_KO_VS_IL10_KO_LPS_AND_IL10_STIM_MACROPHAGE_45MIN_DN | MSigDB lists | GSE5589_IL6_KO_VS_IL10_KO_LPS_AND_IL10_STIM_MACROPHAGE_45MIN_DN | 182 | 39 | 17377 | 2626 |
SEPHS2,SCOC,NIPA2,HAUS4,UBQLN2,ATP6V1B2,WRB,BCAP31,XPR1,SPAG5,UBE2Q2,ATP13A3,HADHB,AKR1B1,SUCLG2,RPRD1B,ALDH9A1,ULK3,ERMP1,DCAF6,SEPT9,KLF10,NET1,LDHA,ATP6V0A1,LNX2,BRCA1,PDE3B,POLG2,PICALM,ECH1,SCARB2,OSBPL11,CHD3,C4orf46,LY75,FAM126A,CDK2,ACSF2 |
| 1.376e-02 | -4.29 | GSE26351_UNSTIM_VS_WNT_PATHWAY_STIM_HEMATOPOIETIC_PROGENITORS_DN | MSigDB lists | GSE26351_UNSTIM_VS_WNT_PATHWAY_STIM_HEMATOPOIETIC_PROGENITORS_DN | 182 | 39 | 17377 | 2626 |
NDUFA5,GCLM,ST13,MUT,MANBA,ARID5A,TATDN3,CHIC2,B4GALT1,NKRF,XPO7,MAP1LC3B,GLRX3,PAIP2,INPP5A,YIF1B,DDX31,ATF2,CTDSP2,RNF169,PDCL3,FYTTD1,LARS,TRIM8,MAP4K4,ECH1,ABHD5,PPP2CA,ORMDL2,ZNF330,QARS,FAM3C,PRDX5,SIL1,ADAM9,SMAD1,CHMP7,PDCD2L,NXT2 |
| 1.378e-02 | -4.28 | REACTOME_CYTOKINE_SIGNALING_IN_IMMUNE_SYSTEM | MSigDB lists | REACTOME_CYTOKINE_SIGNALING_IN_IMMUNE_SYSTEM | 261 | 53 | 17377 | 2626 |
DDX58,NUP188,RAE1,RAF1,NUP54,CUL1,IRF3,IP6K2,LYN,NUP205,HLA-A,CRKL,PTPN2,VAV1,IRF4,NUP210,SHC1,SP100,EIF4A3,PIN1,IL6ST,PIK3R2,NUP107,NUP153,STAT3,NUP85,SEH1L,ADAM17,NRAS,RBX1,KRAS,NUP155,TOLLIP,EIF4G2,MAP2K2,ISG15,IRF5,MAPK3,HLA-B,KPNA4,KPNA1,JAK1,RPS27A,TAB2,STAT1,PML,NUP62,YWHAZ,KPNA2,RNASEL,MAPK1,HRAS,AAAS |
| 1.379e-02 | -4.28 | Translesion synthesis by POLI | REACTOME pathways | R-HSA-5656121 | 17 | 7 | 10287 | 1696 |
RPA2,PCNA,RFC3,RFC2,RPS27A,MAD2L2,RPA1 |
| 1.379e-02 | -4.28 | CTTN (cortactin) | protein interactions | 2017 | 124 | 30 | 17029 | 2761 |
NOP9,ARHGAP17,USO1,EWSR1,SNX2,ACTR3,GSPT2,CUL3,MYH9,CBLL1,WIPF1,CAPZA2,LMNA,RPA1,ANKZF1,RPA2,KEAP1,IDE,SYNCRIP,CHD3,MYO18A,STAT1,DNM2,SUCLG2,ATP6V1C1,ARRB2,ATF2,SMURF1,ABI1,CDC37 |
| 1.379e-02 | -4.28 | GO_TRANSMEMBRANE_RECEPTOR_PROTEIN_TYROSINE_KINASE_SIGNALING_PATHWAY | MSigDB lists | GO_TRANSMEMBRANE_RECEPTOR_PROTEIN_TYROSINE_KINASE_SIGNALING_PATHWAY | 489 | 92 | 17377 | 2626 |
WASF2,RAB14,REPS2,TSC2,ADAM10,RAF1,ACTR3,RAC1,SIRT2,ATP6V1B2,MAPK14,LYN,CPNE3,ABL2,VAV1,ATP6V0B,PDK2,SHC1,CDC42,CD3EAP,PIK3R2,AP2B1,ZFYVE27,TIPARP,ABI1,CDC37,ATP6V1G1,SHOC2,NRAS,POLR2G,POLR2L,NCK1,APH1A,AKT2,HNRNPF,POLR2D,ATP6V0A1,SHCBP1,ZFAND5,GIGYF1,ARF4,SOCS7,IDE,JAK1,RPS27A,ATP6V0C,ACTB,ROCK1,MAPK1,AP2S1,ATP6V0E1,POLR2K,VAV2,SDC2,TIA1,AKT1S1,NCKAP1,AP3S1,APH1B,GTF2F1,PTPN2,FGFR3,PTEN,ARPC5,PTPN11,ATP6V0A2,MVP,STAT3,ATP6V0D1,HNRNPM,SOCS5,PDPK1,TGFB1,CYFIP1,ADAM17,POLR2I,RHOA,MAPKAPK3,KRAS,ADRB2,CYFIP2,ARPC1A,APPL1,POLR2A,MAPK3,PDCD6,ATP6V1D,POLR2J,CSK,ELMO1,ATP6V1C1,HRAS |
| 1.380e-02 | -4.28 | GO_IN_UTERO_EMBRYONIC_DEVELOPMENT | MSigDB lists | GO_IN_UTERO_EMBRYONIC_DEVELOPMENT | 307 | 61 | 17377 | 2626 |
ADD1,ADAM10,XAB2,CCM2,WDTC1,MYH9,EPN1,BCL2L1,CCNB1,CNOT3,CAPN2,RRN3,EIF2S2,DAD1,FUT8,XRCC2,ZNF335,MSH2,CTR9,TMED2,PRPF19,GINS1,SP3,NASP,KAT2A,GABPA,NSDHL,RDH10,CUL3,RTF1,ZP3,ZFAND5,MBD3,POLG2,TRIM28,GINS4,SRSF1,PSMC4,TFEB,MFN2,HHEX,GNA12,KEAP1,SMAD2,PALB2,ITGB1,PKD2,GPI,BTF3,RBPJ,NCOA1,PLOD3,ZMIZ1,NR2F2,ZNF830,MAPK1,CCNB2,SMAD4,ALS2,BYSL,EGLN1 |
| 1.380e-02 | -4.28 | CD2AP (CD2 associated protein) | protein interactions | 23607 | 104 | 26 | 17029 | 2761 |
ARHGAP17,PDCD6IP,NRAS,MTA2,MRPL12,KIF15,KIF23,WDHD1,RACGAP1,CAPZA2,UBE2I,LMNA,NPLOC4,HNRNPR,SH3BP1,HUWE1,CCDC6,SEC24C,RAB4A,PPA2,DNM2,CAPZA1,PKD2,PTGES3,NRBP1,USP34 |
| 1.384e-02 | -4.28 | KRT18 (keratin 18) | protein interactions | 3875 | 119 | 29 | 17029 | 2761 |
YTHDC1,CASP6,DYNLL1,RAF1,WBP2,BRCA1,MCM2,SEC16A,RFC2,MAPK14,GIT2,FKBP3,HGS,HSPA4,SHC1,GOLGA2,HNRNPR,MCM5,RTCB,USP32,YWHAZ,UPF2,KPNA2,ATF2,YWHAH,HRAS,POT1,CDC5L,SMARCD1 |
| 1.384e-02 | -4.28 | NAP1L4 (nucleosome assembly protein 1 like 4) | protein interactions | 4676 | 70 | 19 | 17029 | 2761 |
UNK,KARS,ASPM,CUL3,CUL1,CSNK2A1,CAPZA2,CDC23,MATR3,EIF3A,CAND1,MAGED2,NAP1L1,CDC16,KHSRP,ANAPC7,NAP1L4,FTSJ3,DCTN1 |
| 1.384e-02 | -4.28 | TARBP2 (TARBP2, RISC loading complex RNA binding subunit) | protein interactions | 6895 | 70 | 19 | 17029 | 2761 |
SRP72,PPAN,TRIM41,STAU1,VAV2,AGO2,MEMO1,CUL3,RPL15,C1orf35,PRKRA,APP,STRBP,TCOF1,CFAP20,ZMAT3,HDHD2,GPATCH4,HP1BP3 |
| 1.385e-02 | -4.28 | ECH1 (enoyl-CoA hydratase 1) | protein interactions | 1891 | 109 | 27 | 17029 | 2761 |
LYRM4,COQ8A,COQ10B,MCCC1,LACTB,CHCHD2,NDUFA4,BOLA1,ABHD11,CNTROB,FAM136A,XPNPEP3,ZADH2,LYRM2,APP,PABPC4,RCC1L,BOLA3,PEX5,COQ4,HUWE1,SPRYD4,ATP5F1A,APOOL,PPP6R3,STAT3,EEF1D |
| 1.385e-02 | -4.28 | GSE21033_CTRL_VS_POLYIC_STIM_DC_12H_UP | MSigDB lists | GSE21033_CTRL_VS_POLYIC_STIM_DC_12H_UP | 149 | 33 | 17377 | 2626 |
DDX58,UBE2E2,RPS2,ANXA6,RPS6KA1,CDK2AP2,HEXB,CIB1,RAB23,AGFG1,EZH1,SLC20A1,EEF2K,SUCLG2,CNN2,MED22,NRAS,MLEC,CYP20A1,ABHD11,VKORC1,STK17B,SMAP2,MYO1F,RPA1,SH3BP5,JAK1,FAM3C,MPV17,RPLP1,EYA2,RPS26,HIGD2A |
| 1.386e-02 | -4.28 | SLC25A6 (solute carrier family 25 member 6) | protein interactions | 293 | 114 | 28 | 17029 | 2761 |
COX15,KARS,CYLD,TOMM20,CUL3,STRN4,CUL1,NDUFA4,ADRB2,VDAC1,MCM2,GLMP,LMNA,CAND1,FGFR3,TIMM13,SMAD2,HUWE1,PTEN,AHSA1,ERGIC3,H2AFX,AP2B1,CHEK2,CLN3,ATP6V0D1,CDC37,TIMM50 |
| 1.386e-02 | -4.28 | HEY1 (hes related family bHLH transcription factor with YRPW motif 1) | protein interactions | 23462 | 114 | 28 | 17029 | 2761 |
EWSR1,SNRPB,RPS10,RPL8,EZR,RPL15,CSNK2A1,CDC6,PLEC,SYVN1,SNRPD3,RAB1A,CCT8,RPL11,HNRNPA2B1,MDM2,RPS14,STK38,TMA7,SEL1L,YBX1,DDX5,ACTB,FAU,FBL,RPL22L1,TUBB,DCTN1 |
| 1.387e-02 | -4.28 | GSE29618_PRE_VS_DAY7_POST_LAIV_FLU_VACCINE_MDC_DN | MSigDB lists | GSE29618_PRE_VS_DAY7_POST_LAIV_FLU_VACCINE_MDC_DN | 171 | 37 | 17377 | 2626 |
FGFR1OP,PRPF38B,COX5B,HNRNPAB,TMX4,KCTD17,UBE2Q1,NOTCH2,FAM136A,CCNL2,ZNF518A,RGS1,CCNK,SIVA1,ATG13,CORO1A,ORC3,SAP30,PLK3,IFRD1,LDB1,TBRG4,DCLRE1C,KLF6,STK17B,SYMPK,PDCD6,FNTA,ATAD2,POLR2J,CHD3,HIPK2,PTER,RNF38,KHSRP,PKD2,AAAS |
| 1.389e-02 | -4.28 | BYSTROEM_CORRELATED_WITH_IL5_UP | MSigDB lists | BYSTROEM_CORRELATED_WITH_IL5_UP | 50 | 14 | 17377 | 2626 |
PTPN2,NUCB1,BRD4,POLR2L,GGA1,RAF1,MAP4K4,RPLP1,E2F1,GORASP2,RBBP4,CTDSP2,HDAC2,CBX3 |
| 1.389e-02 | -4.28 | skin-malignant_melanoma | COSMIC cancer mutations | skin-malignant_melanoma | 16216 | 2439 | 17385 | 2587 |
HECA,ZBTB10,ABCC10,HEXB,TGOLN2,CCNL2,FBXO22,EEF2K,THAP4,RAD23B,ATP13A3,DNM2,ZNRD1,FTSJ3,USP34,CCDC57,ERCC1,NRAS,EHMT1,KIF15,HNRNPF,WDHD1,MIER2,DIDO1,MCM2,RAB22A,SMAD2,MID1IP1,RPS27A,MYO18A,OGT,MPV17,SMAD1,ZNF75A,ANXA11,SLC25A33,ZNF720,GGA1,MUM1,CCZ1,TRIO,CUTA,RAB23,KCTD17,HAUS4,EIF2AK4,APH1B,PARN,CDC73,MYL6B,ATG4A,TMEM179B,ERV3-1,PDXP,SMC3,GEMIN4,MVP,NUP85,PPP6R1,PABPC1,NSUN4,PPA1,IFRD1,AGGF1,FOXK1,RBM42,GTPBP4,MAP7D1,MRPL16,ELK1,EIF4H,RDH11,MAGED2,KPNA1,ETS2,TYW5,WIPI2,RUFY3,PDLIM5,ACSF2,FAM72D,EXOC3,RHOG,STARD7,VTI1A,C5orf30,SLC35B2,INO80E,LCLAT1,RCOR3,CPNE3,KIAA1147,RBM23,ZNF420,AHCTF1,TBC1D22A,TBC1D14,GMEB1,NSFL1C,SEPT11,ZNF226,GPD1L,ZC3H3,ARL5A,PDCL3,SNX8,ERMP1,EID1,IDH3A,POLR2D,HTATIP2,MEF2D,TMEM147,GSTCD,TANC1,MAT2A,VPS26B,NSMCE2,CORO1C,CAMKMT,PPP5C,PITRM1,TUBB,COMMD10,ZNF445,SRSF6,HABP4,CCM2,FLOT1,BTN3A1,ATG2B,ABHD14B,PPP1R3B,GOLM1,ZBTB45,HUWE1,ZNF260,ANXA5,LTN1,KANSL2,UBE3B,NAP1L4,ZNF710,ST8SIA2,MED22,SPTAN1,STAU1,DDX24,TCTEX1D2,TACC1,MRS2,LDHA,HEBP2,LLPH,RAB3IP,TTC33,PICALM,SH3BP5,SLC19A1,ACOX1,FAM3C,AEN,PARP10,YWHAH,THAP5,GPATCH4,FAM129A,TRIM11,YTHDC2,SNX15,RBM8A,ENSA,NENF,SND1,RUFY1,TRIM65,ZER1,PRNP,KRR1,RAB8A,NUP210,NT5DC1,NOC2L,EIF5,TACC3,RYBP,VPS13B,PTPN18,MIOS,MBLAC2,SNRPB,CDC6,UTP3,PBRM1,ODC1,USP21,TRAM2,FBXO28,BCL7C,ARRDC1,ADAM9,DVL1,NUMB,ZNF564,FUBP1,C1orf74,CTU2,PARP12,ZCCHC9,CENPF,LAMTOR3,NCKAP1,RSAD1,TNS3,SUB1,RINL,SSBP3,KIF13B,MBD2,XPA,AHCY,RBM3,GLE1,LRSAM1,HDHD2,NTPCR,NSDHL,AMD1,CAMSAP1,ZNF761,METTL22,ICAM2,STYXL1,APPL1,BBS12,ANKRD46,RXRB,SDHB,PCM1,GALNT2,TMEM168,NLRC5,RUVBL2,BTBD10,MYO9A,CCNB2,USP7,GLT8D1,RPLP2,SUCLG1,ARID2,TMX4,SLC2A1,ATP6V1B2,PCBP1,LYN,BCAP31,VAV1,TMEM69,MRPL50,PSMA6,ZNF473,ZNF302,BRPF3,TARDBP,BCAP29,CTDSP2,PRPF19,PPIF,KDM3B,MND1,CLCN3,BIRC3,RAB7A,ANKRD33B,PPIE,CHMP2B,VDAC1,EIF3H,TMEM201,GLOD4,IDE,DHX16,UHRF2,CHMP4B,XRCC3,PARD3,BCL2L12,C19orf53,MCM10,KLHL21,PDAP1,CDCA8,TMX3,ARF1,SLC12A9,TUBGCP2,DNAJB9,HOMER1,WBP1L,POLR1B,RNF5,RBM15B,PPAN,RHOA,RPRD1A,BTAF1,TOP3A,ARHGEF12,PCGF1,DDX23,RAB18,CACNB1,TRIM26,PDCD6,ATP6V1D,L3MBTL3,FAM110A,NEIL3,CTBS,BBX,IMPDH1,NR2F2,PGAM1,HIPK3,IFI16,NUP188,H2AFZ,PNISR,TMEM203,PRKCSH,USP39,UBE2I,PARK7,SLC25A37,ASPHD2,ZNF428,RAB4A,TRA2B,SUCLG2,CISD2,TAF5L,SMARCE1,ZNF800,CDC5L,ZNF524,SGCE,OSBP2,NSUN2,USP22,CLNS1A,EIF3A,ZMYM3,DOT1L,IWS1,ANKRD10,WAS,KIF18B,TPP2,C1orf109,ZMAT3,B4GALT2,PRPF38B,RECQL,C9orf78,EWSR1,GADD45G,RRM1,ACAP1,B4GALT1,CYCS,FAM136A,SUPT7L,TMEM165,NPLOC4,CNOT3,SPAG5,WDR48,RTKN,CEP104,EXOSC7,KLHL5,LRRC8D,PPP4R1,MSH2,PIGG,OSTF1,FBXL7,MRPL40,TNRC18,SYTL3,FAM171A1,APOL1,EIF5A,GCC2,PRIM2,ELL2,RDH10,MFNG,RPS24,GORASP2,CAPZA2,ADRB2,CCT8,MTR,PHF6,PFDN5,SLCO4A1,TTC13,GOLGA2,RBMX,MED15,PIAS2,APPL2,SAMD8,NUDT3,CDKN2A,ZNF511,ATXN3,RAF1,KIAA0232,C2orf49,CD320,EPM2A,CCNA2,MTMR4,TP53BP2,AQR,RBM12B,ILKAP,CDK12,SAP30,BRD4,NARF,LRRC8A,ELP4,ABHD11,PKMYT1,ASB13,TRIM28,SUPT16H,EIF3K,CHMP4A,CBWD1,ATF6,XRCC4,ADAM23,PRPF4B,NDUFS1,DEPDC1,MECP2,SECISBP2,HMG20A,WWP2,JAKMIP1,SLC25A36,CCNK,DNAJC8,ELP5,AXIN2,CITED2,JMJD4,KAT2A,RABIF,ADSL,PACS1,BMS1,KCNQ1,OTUD3,ARSK,MACF1,KIF11,COMMD4,KLF6,SMAP2,FADD,SH3GLB1,MYO1F,CBX3,TMEM127,INF2,PPP1R11,DUSP11,DDX5,WDR62,TAF6,ESPL1,PURA,DDB1,DEF6,IPO4,FAM83G,UBL3,NAT9,PIGM,LYRM4,GPR132,UBE2Q1,PTP4A3,MRPL19,ZNF696,SF3B2,PCYOX1L,CDC42,SYNM,GOT2,JAZF1,HADHB,RPF2,SLC35C2,CNNM3,CARM1,SRPK2,WDR41,LARS,ZCCHC10,CCDC138,LRBA,TMEM216,SUMF2,KMT2C,OGFR,PRPSAP1,ASF1B,RPL37,MAN2A2,EIF4ENIF1,U2SURP,MIA2,ZNF268,VPS4A,ATP6V0E1,PPP1R2,PM20D2,XPNPEP3,RGS2,LYAR,FAM89B,POLR2I,TRAFD1,SUGP2,GBA,EIF2A,SYVN1,DAPK3,ARHGAP15,MASTL,UAP1,NFIL3,FN3KRP,YWHAZ,CTSA,TMEM14A,TOB1,TSEN15,ADNP2,TCF12,PRKAB1,MDH2,SMARCA4,ORC1,RRN3,UBXN2A,IARS,CD3EAP,KIF14,EXOSC1,CS,CLTB,DNAL4,CSTF1,POU2AF1,UBQLN4,NXT1,HPDL,PGGT1B,SELPLG,SMU1,ATXN1,GLO1,OGDH,BICD2,CADM1,EDEM2,HERPUD2,TOLLIP,FANCE,MBD3,PDHX,RPS9,ALKBH6,DUS3L,ARNTL,FKBP5,TMEM101,CCDC125,ABCA1,PDCD2L,GCLM,RAE1,DCTN2,NUP54,CHIC2,PAWR,MXD4,DCUN1D4,PIP4K2A,XPR1,FERMT3,KIF5B,KLHL20,SEC24C,RRBP1,ARHGEF2,ANP32A,LDLRAD3,STAT3,MYO5A,NIPAL3,AMPD2,TXNL1,PHF20L1,DCAF6,FAM49B,TMEM39A,ATP2C1,RFFL,COG1,RCOR1,PRMT2,TFEB,LEMD2,UPF1,ELMO1,ZC3H7B,DTX4,ZMIZ1,TERF1,HRAS,CCDC93,FGFR1OP,TMED7,PIGQ,AGPAT1,CNTROB,PPP1R16B,GSDMB,TTC9C,PDS5B,NUP153,SENP1,PGAP2,TMEM115,PLEKHM3,DCUN1D5,PLEKHF2,BRMS1,PWWP2B,TRIM47,WDR11,AXIN1,SMG9,TRIM52,LONP2,NDUFV2,PHF23,CERK,SLC4A2,EZH1,ITGB5,LMNA,MCTS1,DDX56,SLC38A5,FOXN2,CARS2,PRRC2A,C16orf72,RB1CC1,ZMYND11,PGS1,MYBL2,UHRF1BP1,SRSF5,MPG,MATR3,CYB5A,NCDN,POLR2J,SETD3,TEX30,PTAR1,CNOT6,NDE1,EGLN1,ZNF207,ANKRD27,ABCA3,SARNP,IVNS1ABP,RMI2,MON1B,TMEM97,NIT2,NUF2,ZNF267,TCF19,TMEM161B,KTN1,APP,PRKD3,CLUAP1,ATP2A2,UTP18,GRSF1,DUT,ZCCHC2,ANAPC7,RNF19A,FAM76B,CLN6,TMEM9,GCC1,RNF169,ADCY7,ATP6V1G1,ENPP4,RNPS1,CDCA2,FKBP3,GPR137,DDX17,CHCHD3,PEX5,CDC16,HIPK2,MBOAT1,TICAM1,PDXK,ZBTB11,ANXA6,TMBIM4,GMCL1,UBE4A,IL21R,ETS1,WRB,ZNF92,PNO1,CAPN2,ADD3,SUV39H2,TTLL12,TPCN1,TMX1,LYPLA2,HNRNPM,MFSD12,LDHB,PPP3CA,POLK,EMP3,MTMR12,ZP3,PDE3B,KIF18A,CCDC6,WNT5B,MAPK6,C4orf46,LY75,SLC25A19,RGL1,PSAP,WDR76,IGBP1,FAF1,COX15,AGRN,GNPDA1,GPBP1L1,PPP1R15B,CSNK2A1,EBNA1BP2,GIT2,BIRC2,ATPAF1,DLG5,ABL2,XRCC2,ZFYVE27,MCMBP,PTPRK,CDC37,METTL1,SP3,EXOSC6,HARS,GMFB,ESYT1,ANLN,RAB5B,RHEB,DPYSL3,TBC1D17,TIMM13,CDCA4,TONSL,NRM,NAGLU,ACTB,ZNF45,TMUB1,CTCF,ASAH1,DOCK11,CRLF3,ASXL2,LRRC14,NUS1,SLC27A4,AFF1,MDFIC,MAML1,CYTH1,NQO2,UTP15,EIF2AK1,EIF4G2,ZDHHC3,MOSPD3,ITPRIPL1,CDC27,TBPL1,PRMT7,KCTD7,CYLD,UGP2,COPE,ZADH2,GGPS1,RAD23A,ATP6V0B,PDK2,STRBP,DUS4L,PDCD2,SAP30L,SLC39A9,CLPTM1,RPL29,RPL35,BTG2,DNAJC9,MTMR6,NFATC2,KDM1B,ARL5B,USP36,CCDC127,MRPL2,ATP1A1,CLK3,PSMD3,MAFK,CEP55,NDUFA11,DNAJC17,ZNF436,NCOA1,SLC25A39,ZC3HC1,ZNF146,ATXN7L2,CDC40,GOLIM4,SMAP1,RRP15,GNE,SMC6,ARFIP2,NKRF,CHAC2,BZW2,WRNIP1,SS18L1,CENPM,CAMK2G,MLEC,ZNF202,PPWD1,FAM50B,RHOT2,NEU1,TPD52L2,GOLGA7,TWSG1,GLG1,PGRMC1,FAM126A,RPS6KC1,UBE2C,PPCS,TMEM41B,ZDHHC8,PLXNA1,CCNB1,SLC20A1,COMMD6,POLR3K,C14orf119,ASAP2,SNUPN,CNPY4,PLCL2,TFG,SEH1L,ATG9A,PBK,MKI67,DDX20,AMDHD2,GALNT7,SLC17A5,CCNF,FOXRED1,RBM47,PTER,WDR4,DHTKD1,TRAF5,HDAC2,PWWP2A,HSPH1,LIME1,MAPRE1,CHTF18,ADO,KIF23,SLC35B1,NOTCH2,PMF1,JMY,FKBP1A,SLC31A1,SNX18,ATIC,CTPS1,ATP6V0A2,PIKFYVE,RNF135,LPCAT1,EEF1D,TMED2,FTL,PHF10,DDX28,SIGMAR1,PIP4K2C,FAM133B,RIT1,PLEC,KDM3A,SF3A2,FAS,EPRS,ZNF777,TMEM54,QARS,PPP3R1,TCOF1,NRBP1,CABLES1,DNMT3A,RWDD1,CKLF,TRIP10,SF3B1,RPS6KA1,CAST,SUZ12,RAC1,GPR89A,OLA1,GNB2,FLAD1,APLP2,KDM2A,TNPO2,CDKN1B,TALDO1,ATP13A1,MAPRE2,RFC3,ERF,CUL3,SLBP,KIAA1586,H2AFV,POLG2,GAR1,PSMB9,DHX57,NSA2,HSPA4,MRPL55,JAK1,TBL3,GOLGA8A,SEL1L,H2AFX,KLHDC4,B4GALT3,PDCD11,ATMIN,POLQ,POU3F2,OTUD5,NCOR2,ANKRD13D,PKP4,SCAMP3,BABAM1,CDCA3,SLC25A12,BLM,TMCC3,GTF2F1,RPL17,CRAT,AHSA1,PRC1,UPF2,COPS7B,SLC38A10,CNOT6L,CNPY3,UBE2M,IFT46,TMEM160,TSHZ1,ZFP64,STRIP1,DENND4C,DENND1B,WDR18,RPL8,ILF3,LRRC1,RHOT1,MARK2,TSR2,ECH1,PRDX1,PLD3,NUCB1,FBXO21,GNA12,C1orf131,PRDX3,PFDN4,HNRNPH3,STX18,TFDP1,KHSRP,ASNA1,CPEB2,SSSCA1,VPS29,BYSL,S100PBP,MIB2,IER2,NOP2,UBN1,DCAF15,NF1,FLYWCH2,ALKBH5,MOGS,UBE2Z,TAF6L,BECN1,MAPK14,SNAPC4,RNF103,BCAT2,MBD4,METTL14,ZNHIT6,IMPAD1,RCSD1,PHTF1,SRI,KIF22,ZBTB22,NFU1,OGG1,TRIM14,ELOF1,COPS8,FYTTD1,TRIM8,RRM2,SOX4,ABHD5,UBTF,CXXC4,PAF1,UEVLD,SPATA2,PQBP1,IARS2,ATXN2L,GALNT10,STARD3NL,RPS15,PIGN,AGTRAP,CIB1,XPO7,SRRT,ZNF449,CAPZA1,KIFAP3,BCL2,N4BP2,HP1BP3,VOPP1,THNSL1,ISG15,CAND1,GNAS,TSC1,RBM25,CDCA5,ZFP90,NANP,RBBP4,ZBTB24,SMARCD1,MBD1,WASF2,MMACHC,TOMM20,IFI27L1,MPHOSPH8,HNRNPUL2,CHD1,MEAF6,CCDC50,AKAP8,PARL,RPN2,CHTOP,FAM3A,F2R,SCYL3,ABI1,HTRA2,MOSPD1,RLIM,FAM172A,ZNF500,PSMB7,NLN,WIPF1,BOLA1,BUD13,NDUFB1,PEF1,EIF3G,BTBD1,TAB2,CHCHD1,TULP3,WDR59,CANT1,SCARB1,GAS2,USP11,SMURF1,PPP2R2D,TSPAN5,CDS2,MAGEH1,MRPL42,EYA1,CDK2AP2,MRPS26,LETMD1,KLF13,HDDC2,RGS1,MAN1A1,FBXO5,GART,PELO,TANK,BRD7,MRPL11,SAMD4B,ZDHHC18,GTF3C6,POLR3GL,WDR81,MEN1,ZNF407,MFN2,COX8A,ZRANB2,SRSF3,MBD6,ATP6V1C1,IDH3B,TATDN1,TSC2,LACTB2,CMTM6,RBM4,ZNF275,ANKRD39,CDKN2C,USF1,DNAAF2,MECR,AP1M1,UPRT,CRY2,ECD,RNF26,TIPARP,LRRC59,RHBDD2,MGAT5,BAK1,ZNF559,RHOBTB3,GABPA,WBP1,NUTF2,ARF4,GINS4,KRIT1,AHNAK,RAD18,PDRG1,RNASEL,CHPF2,PDCD4,NXT2,HIVEP3,KIAA0100,CLSPN,RHOC,DHX9,PDCD7,PSMD9,HAUS2,COPB2,TFAP4,CD59,RNFT1,RIMS3,MEGF8,EFTUD2,FBXO7,CPSF4,MRPL21,PHKG2,LUC7L2,SRSF11,EIF3L,MTA2,TYW1,USP10,ITM2A,SSR2,BCLAF1,MTX1,SFXN5,FNTA,PDLIM1,TXNDC16,ZNF830,TMEM159,MRPL3,ALS2,FAM72A,TRIM41,KARS,NQO1,POC1A,ANK3,PTTG1,TPX2,TBC1D13,DAZAP2,GLRX3,STMN1,C19orf48,REPS1,ABHD16A,FBXL6,SH3BP1,MTA1,UBA5,CLCN6,INTS12,RPRD1B,SZRD1,CGGBP1,CPNE1,FAM118B,GOPC,E2F3,CIRBP,RPL38,CRNKL1,PFKFB3,GORAB,RAB1A,GIGYF1,TMEM184C,PPP2CA,KIF2A,CCDC14,LSM6,RNF38,SNRPG,DMWD,USP13,MZT1,ZFP91,TRMT6,IP6K2,WDR5,SLC25A43,IFT27,PMVK,NEIL2,RRP36,SRXN1,RPA2,PSMD2,CLIC4,PDCD10,COQ4,ITGB8,ARF5,ARHGEF1,GTF2H2,FBXL19,TTPAL,UTP20,MAGT1,GPS2,DBI,SSNA1,CD81,TMEM131,WDR13,FANCI,PAPOLA,CREM,FANCL,TET3,GLIS2,IL6ST,INTS1,POP7,SLC44A1,MTPN,ASB6,PLK1,RPP25,CELSR2,SEPT9,RBX1,APH1A,RAD51AP1,ZBED5,CKAP2L,PSMG1,UBE2V1,EAF2,IL12RB1,LUC7L,LSG1,NECAP2,ALG3,TRIM4,AGPAT2,CHD3,ZNF367,E2F4,PRPF4,KPNA2,BEND6,CLN3,DNAJC30,FAM208A,NGLY1,POT1,MYL12B,CCDC137,RMND5A,HJURP,PHB2,DNAJB2,FAM53C,NKD2,SDC2,KLC1,CDK13,ADCK5,COX4I1,DNAJB1,RAB6A,ARID1B,C1GALT1,MLX,UBE2Q2,CCP110,ZNF746,ARL6IP1,CTR9,NIPSNAP1,ABHD2,DCAF8,ACSL3,LDB1,MAP4K3,ARMC8,RBM38,NMT2,IRF5,HAUS8,MBIP,ORMDL2,COX7A2L,ZDHHC7,SIL1,FAM122A,DTD1,UNC13C,BCCIP,SART1,TRAF7,NDUFAF2,TOR1AIP1,ZNF416,LAGE3,TM9SF3,ZFYVE21,RRAGC,ZNF121,OIP5,NRF1,WDR44,PPME1,PIN1,EFCAB11,RPAP1,CABLES2,LMAN1,AHCYL1,TOP1MT,STRAP,SPSB3,ZNF583,SNX25,ARHGAP17,POLR2G,ZNF780B,PPT1,NUP155,DCLRE1C,MRPS14,RHBDF2,SUGP1,RBL1,FASTK,UBXN2B,STK38,AP1S1,SPRYD4,SLC22A23,H3F3A,CHID1,SMAD4,RAD51D,SLC30A9,UNK,CMAS,NADSYN1,HMGN3,NCAPG,SCYL2,FZD6,HERC3,GTPBP3,CTSS,ORC3,RNLS,YTHDC1,ACP2,HMGN5,CSRP1,METTL5,ABCF2,TUFM,RANGAP1,PNPLA8,HAGH,API5,ZFR,SEC23IP,E2F1,TMEM219,USP20,RBPJ,PDCD6IP,MAX,LUZP1,GXYLT1,ADAM10,CXXC1,TSC22D3,AP3M2,CUL1,GYG1,NANS,OAT,MYEF2,ANKRD26,PA2G4,NOL11,FIZ1,ZNF200,MARCH2,SLC26A2,SRP72,KLF10,LACTB,CBFB,RFC2,RAB2B,PRIM1,MAP3K4,HHEX,LUC7L3,RPS14,MAP4,MRPL27,BTF3,PTPDC1,NMD3,CCDC59,PTOV1,COX5B,DNAJC5,SCOC,DHPS,ANKH,C16orf87,VAV2,PRKAA1,GSPT2,TATDN3,DLGAP4,PXMP2,PRPF39,PSEN1,ZNF79,PDXDC1,VPS25,NDUFS7,YY1AP1,C12orf10,FAM192A,RPN1,LHX8,ARPC5,TPST1,DAPK1,CYC1,SOCS5,FDFT1,PIGT,EMB,WDR1,ZNF574,EXOSC9,ARID1A,PTTG1IP,C9orf40,FXR1,GOSR1,MAP2K2,TWISTNB,AKAP1,XRCC5,HMGN2,PI4K2A,CAT,DERL1,MTHFD2,HSPBP1,CEBPG,ARAP1,USP32,FAM83D,CABIN1,SMPD4,GPI,CYTIP,TP53RK,REPS2,RAB11B,UROD,SLC39A13,BCL2L1,DECR1,RALB,SIAH1,ADCY9,LPIN2,MRPS27,SOCS6,TTC3,RNASEH2A,CFL1,ANKLE2,CDC123,OAF,VDAC2,EDF1,ERC1,AMZ2,ANKZF1,RAD51C,ZNF282,DSN1,DDOST,HINT1,DGCR8,SAFB,RWDD4,FTSJ1,LMBR1,NCLN,BEND3,EYA2,DYNC1LI2,MANBA,B4GALT5,SLC41A1,FAM76A,TKT,CBLL1,ARGLU1,LANCL1,POFUT1,FAM8A1,HEATR5B,HLA-A,EBP,RFWD3,NDUFA2,FJX1,FUT8,PTPN11,MRPL54,FEM1B,RPL19,CNN2,MTX2,MSH6,PDLIM2,LONRF3,RFXANK,FBXO9,GUF1,RPL32,ZHX1,OAZ2,NDUFS5,WDR91,GPR89B,RORB,POLA2,ZNF76,MTX3,COPA,UQCR10,PHRF1,ABCB10,COMMD5,MAP1LC3B,DST,RAB35,SIVA1,GPATCH1,TCEA1,DRAM2,DEAF1,TRAPPC13,SNRNP200,LAP3,NCK1,VHL,SREK1,ARHGDIB,PITPNB,BRWD1,PPM1G,SH3GLB2,BAZ1B,CAB39,ACBD4,STK11,CLU,CHEK2,ZSWIM3,TSTD2,MRPL13,CHPT1,DCAF5,CAPN1,UBE2D3,NSMCE4A,PPP1R12A,ZCCHC8,GORASP1,NACA,UBXN1,RPL15,PCSK7,EPN1,THRAP3,QSOX2,TTF1,NUP205,PRPF18,CHKA,DTL,ZRANB1,MCPH1,SLC12A2,ATP6V0D1,CSNK1G3,CREG1,NUDT4,RPL6,SLTM,EVC2,KLHL15,SIAH2,SLC16A1,EHD4,SNRNP70,C11orf1,APOL2,N4BP2L2,SNX27,CORO7,FEZ2,UCK2,PMS2,UCK1,CLCC1,EXT2,MXD1,USP5,HNRNPA2B1,SAP130,NVL,PPP6C,CYB5R1,ZNF770,EBAG9,RNF25,PCGF6,METTL2A,PON2,HNRNPR,HPS5,STAT6,MAPK1,BRD9,TMEM33,NAT14,DNAJC2,TRIP12,SHPRH,SCYL1,VPS45,MYO9B,GFM2,SPPL2A,FASTKD3,FGFR3,PPIG,ZDHHC13,TMEM99,H2AFY,ATG13,NDUFS8,ERI3,FBL,FRMD8,SLC35A1,MICAL3,TGFB1,B3GALT6,ELOVL5,HEMK1,TIMMDC1,HELB,PSPC1,MIER1,SCFD2,NDRG3,CDK11A,MTMR3,MEGF9,CENPT,PLOD3,RAB3IL1,RAB14,ADD1,MRPS15,KDM4A,XIAP,DHX8,GLUD1,PABPC4,CALM2,CDK5,PSMD1,NEK6,NSRP1,RABGAP1L,SRSF4,FNIP2,KCNAB2,PCBP2,MLST8,PLK3,ZNF672,MRPL43,HSDL1,TOPORS,MCL1,SMC2,PPFIA3,ICMT,SLC50A1,STOML2,LIMK1,ZNF689,PRDX5,ATE1,MLYCD,ATP6V0C,ST3GAL2,FBXL3,TFDP2,E2F2,PFKP,AAAS,DDX42,SSRP1,MRPL9,MRPS2,STRN4,TOP2B,ZNRF3,TMED3,DDRGK1,RAVER2,GNS,INTS7,INPP5A,MCM5,PHF14,ZNF326,NAGPA,ETV3,TSPYL4,DHX29,TEX10,MAN1B1,CBFA2T2,ABCF1,RHOB,LRRC14B,DTWD1,PTPRF,SCARB2,OSBPL11,CCDC86,DUSP3,SLAIN1,MDH1,HEXA,RNF139,SNX14,ZNF296,TRERF1,UBR2,CHD1L,ACTR3,WDTC1,MYH9,PRKACA,SAFB2,ANKIB1,STAM,ARL6IP6,RAB21,SP100,ZKSCAN1,DDA1,NUP107,ANKRD13C,MAVS,CEP63,RBM15,ATF2,DCTN1,SHOC2,MAP4K4,WBP2,ATP6V0A1,NUSAP1,DNAJA1,TAZ,C19orf54,TAF2,SEC61A1,WDR7,CBLN2,FUS,GEN1,LRP8,COIL,LRCH1,GALK1,ZNF786,RPS2,SESTD1,TRAK1,JMJD6,SIKE1,AKT1S1,KRI1,FBXO3,ERH,GATC,NDUFB4,PPP1R8,PRDM4,GTSE1,GEMIN6,DCP1A,SGCB,S100A6,IMPA2,NUDC,PDPK1,TK1,GUK1,TNFAIP3,GALC,ZNF512,KIAA0930,MRPS10,DDX39A,RPA1,ZNF862,ZNF180,KEAP1,POLE,TATDN2,PITX1,CAPN7,LRPPRC,PML,HMGB2,USF2,ANAPC4,SRM,DDX47,MCCC1,CDC42SE2,S1PR2,CDIPT,SEC16A,SSR1,LIN9,PCNA,ZNF639,TRMU,PIK3R2,ETV6,TXLNA,PPCDC,FAM86C1,MYBL1,MRPL32,CCAR1,ABCC5,PBXIP1,BAZ2A,TLK1,MRPL12,EZR,LNX2,LRP5,BRCA1,PRKRA,STX16,EPB41,OPTN,SEPT1,SOCS4,QRSL1,OSGEPL1,GLCCI1,NUDT11,NAA60,GEMIN7,SEPHS2,LZTR1,RACGAP1,PPP3CB,B4GALT4,RLF,RAPGEF6,RB1,VASP,MED8,VMP1,PPIL2,MEA1,TIMELESS,AHDC1,ALDH18A1,TMEM8A,ABCC1,PREB,TRAPPC9,AACS,MEMO1,KRAS,RTF1,UBE4B,NFATC2IP,LY6E,ARPC1A,ZNF174,PSMC4,GOLGA4,PALB2,SYNCRIP,PRPS2,NIPA1,TIGD2,RNF114,FOXM1,MRPL39,XAB2,SUMO2,DUSP22,COMMD8,RPL11,CSDE1,MDM2,CORO1A,METTL9,MINPP1,POC5,DVL2,GM2A,PSMA8,COQ10B,CPOX,TIGD5,SLC26A6,CYP20A1,PRPF3,TXNL4A,RPSA,SRSF1,DNAJC10,ZNF700,SCAP,PLEKHG4B,TIMM17A,LTA4H,AP2S1,USP53,INTS2,CTDP1,CDT1,ARID5A,SUMF1,GGA2,AP3S1,CSNK1A1,RMI1,TFRC,PTPN2,IRF4,GSTK1,NDUFV1,SLC1A4,CWC27,SLC35B4,DDX31,ABCD1,RPAP3,CNTN5,SNX2,ZMYM5,CHCHD6,BSDC1,KPNA4,FBXO41,BIRC5,TFE3,SNAP29,CDCA7L,PKD2,ACADM,CHMP7,SAT2,ZNF496,TMEM109,TAP1,YTHDF3,NHLRC3,IKBIP,ELMOD2,KIFC1,DBNDD1,CYB5RL,PARPBP,CDC25B,PRADC1,DNMT1,NOL12,ORAI2,USO1,AKT2,NOL8,GNG7,AURKB,SLC25A5,ZFAND5,MAK16,STT3A,TMED10,EIF2D,ITGB1,PTPN7,UQCRH,RRS1,ARRB2,RTN3,ZNF598,DDX58,WSB2,PPIB,MUT,GMFG,HLA-E,NDUFA4,MAN2B1,METTL3,CFLAR,NDUFS4,RNF121,MEX3C,KLF16,HDAC7,DAD1,BDH1,PCYT2,GNAI2,ANKHD1,MORC3,TERF2,KCTD20,SEPT8,DCTD,PKM,TOMM40,PATL1,ADSS,SERTAD2,ZFP92,ERGIC3,ACLY,LPCAT4,VCPIP1,YY1,PPP6R3,PPP6R2,MAP3K5,RNF14,CDK2,ZC3HAV1,SYS1,ZBTB37,URB2,EIF3D,MAGED1,KLHL18,ADPGK,SLC25A44,AP1B1,SDHA,PAIP2,PHC2,CRKL,TERF2IP,MOAP1,CYHR1,ZNF75D,SHC1,UCHL5,NAA35,CCT2,CDKN2AIP,MKLN1,HMGN4,LYRM1,GALK2,CDC23,SHCBP1,AP4E1,PRDM11,VEZF1,PPP2R5A,ACYP1,STAT1,PPA2,TRIM32,RHEBL1,R3HCC1L,C1orf112,TCF3,MRI1,BRAP,AGPAT3,MYNN,SDF2L1,SPR,RAB11A,REEP5,FOXO3,MAD2L2,CCDC28A,PIP5K1C,RBM17,MAT2B,PTEN,CENPJ,TAGLN2,PACS2,NCOA2,SMC4,RNASEH2C,NEK7,NET1,PARP4,TBRG4,ANAPC2,RPL27A,YIF1A,SGSH,HGS,TTLL4,SLC38A7,MFAP1,CCDC69,BRWD3,ESYT2,SKA3,NPHP4,UBE2E2,HNRNPAB,PLXNC1,ST13,TMEM184B,DNAJC24,ZNF107,SLC29A1,KIF2C,AGFG1,SIRT2,FKBP2,USP48,UBQLN2,CUTC,EDC3,UBLCP1,ZNF804A,RAP1A,THADA,EIF4A3,AP3S2,ATG3,DPYSL2,PPP1R12C,AKR1B1,NDUFB9,RP2,TTC4,TECR,ARID4A,FGFR1OP2,TIMM50,TDP1,DPM1,FOPNL,SLC16A7,WDR82,STK17B,DHX15,CHAF1A,GEMIN5,COPS6,SASS6,RPS26,PSMC1,SLC12A7,TBC1D12,TM9SF4,ZNF768,UFC1,MED13L,TIA1,MEF2A,EPHX2,PITHD1,RHBDD1,NFATC3,BANF1,ZNF335,BUD31,YBX1,KNTC1,ACAD8,UBE3C,ZNF189,ALDH9A1,KDELR1,TSTA3,CIC,OXR1,SEPT7,NAP1L1,NSMF,ODF2,EXOC4,KIAA1328,NUP62,PITPNA,PTDSS1,PDSS2,C7orf26,TMEM106C,IMMT,ASH1L,CHERP,WDYHV1,PLAGL2,CHKB,IRF3,TWF2,PAIP1,ANKRD28,ANKLE1,FARSA,SAR1A,SCAMP4,APOOL,PDIA6,ACSL5,TOR1AIP2,AZI2,GFER,RAD54B,TMEM41A,DAP3,ZNF317,GADD45B,AKNA,REEP4,CBX4,KIF3B,GOLPH3L,SH2D3A,CASP6,TOR3A,SRGN,DBF4,MFSD10,SAC3D1,CTNNBL1,YIF1B,CLDND1,TTC17,SLC25A1,GINS1,PAQR6,CSNK1G2,TELO2,ADAM17,HMGN1,NASP,ASPM,PPP1R21,PRKAR1B,SYMPK,TARS,SNRPA,MAPK3,HLA-B,ATAD2,PLAA,ZNF330,OSBPL8,KBTBD7,PREPL |
| 1.390e-02 | -4.28 | cell cortex part | cellular component | GO:0044448 | 163 | 35 | 18223 | 2701 |
EXOC3,MAPRE1,SLC2A1,FLOT1,MYH9,SAPCD2,RTKN,TMEM250,CAPN2,SH3BP1,RALB,RIMS3,SEPT11,CORO1A,CLTB,GM2A,CFL1,DCTN1,SPTAN1,SEPT9,WDR1,SEPT8,EZR,WIPF1,CAPZA2,ANLN,SEPT7,EPB41,SEPT1,WAS,NSMF,EXOC4,PKD2,MYL12B,UNC13C |
| 1.390e-02 | -4.28 | CAV1 (caveolin 1) | protein interactions | 857 | 191 | 43 | 17029 | 2761 |
TSC2,NF1,RHOC,DYNLL1,VAV2,RAC1,STRN4,NKD2,FLOT1,CSNK2A1,PRKACA,APP,TFRC,PRNP,RPA2,GRK2,PTEN,PTPN11,GNAI2,F2R,FGFR1OP2,ABCC1,RHOA,RAB7A,TMEM216,MCL1,VDAC1,TOLLIP,MAPK3,RPA1,FAS,AKAP1,PTPRF,PPP2CA,DERL1,SMAD2,PLAA,CSK,AXIN1,ACTB,MBOAT1,MAPK1,HRAS |
| 1.390e-02 | -4.28 | GSE34156_UNTREATED_VS_24H_TLR1_TLR2_LIGAND_TREATED_MONOCYTE_DN | MSigDB lists | GSE34156_UNTREATED_VS_24H_TLR1_TLR2_LIGAND_TREATED_MONOCYTE_DN | 160 | 35 | 17377 | 2626 |
CDS2,GXYLT1,ARGLU1,COX4I1,SECISBP2,FAM136A,EPHX2,WRNIP1,USF1,NDUFB4,HUWE1,IL6ST,RBM34,PPIL2,BTF3L4,CNPY3,IFT46,MSH6,ABCC1,UTP15,RPL38,ZBED5,DCUN1D5,PPWD1,POLG2,GAR1,EIF3H,RPSA,RAD51C,SEPT1,PRDX3,CERS6,UHRF2,PPP6R3,ANAPC4 |
| 1.390e-02 | -4.28 | GSE32901_TH17_EMRICHED_VS_TH17_NEG_CD4_TCELL_DN | MSigDB lists | GSE32901_TH17_EMRICHED_VS_TH17_NEG_CD4_TCELL_DN | 160 | 35 | 17377 | 2626 |
SLC12A7,CYTIP,SUMF1,IP6K2,DNAJB1,BZW2,ATPAF1,NPLOC4,NAPG,RAB8A,FBXL6,CISD2,CPSF4,ABI1,FGFR1OP2,PREB,ABCC5,MLST8,NIPAL3,ABHD2,TNFAIP3,GABPA,DENND4C,NEK7,NDRG3,PDE3B,ECH1,ARAP1,CTSA,SLAIN1,NDE1,PDLIM5,COIL,RAD51D,EGLN1 |
| 1.391e-02 | -4.28 | V$GATA1_01 | MSigDB lists | V$GATA1_01 | 227 | 47 | 17377 | 2626 |
KIF3B,IMMT,FEZ2,PLXNC1,TRERF1,SRSF6,TOR1AIP1,ANK3,TMEM97,CTCF,PTP4A3,DOCK11,RAPGEF6,CNOT3,ADD3,DPYSL2,MSH2,TNPO3,YBX1,MRPL40,C12orf75,ZNF800,CPNE1,SP3,AKT2,KAT7,PPP1R21,VDAC2,ARL5B,MAK16,DHX15,NCDN,SUPT16H,MAGED2,VEZF1,HHEX,KPNA4,CDC27,SYNCRIP,RBMX,OAZ2,PRDX5,ACLY,SLAIN1,CLU,TSPAN5,ATXN7L2 |
| 1.391e-02 | -4.28 | CTTTGCA,MIR-527 | MSigDB lists | CTTTGCA,MIR-527 | 227 | 47 | 17377 | 2626 |
TCF12,KIF3B,MAPRE1,IVNS1ABP,MECP2,ACTR3,CHIC2,CDK13,MAPK14,SEC11A,RAP1A,KDM2A,PTEN,ZNRF2,PRC1,SEPT11,TARDBP,RP2,MAP3K14,ZNF800,SRPK2,FYTTD1,TACC1,NUDT4,IDH3A,MEMO1,ATXN1,PBRM1,MEF2D,BICD2,OGDH,PLEC,API5,RHOB,PHF6,MKNK1,KPNA4,L3MBTL3,CORO1C,MAFK,STK38,PITX1,LPCAT4,RNF38,IMPDH1,WIPI2,B4GALT2 |
| 1.391e-02 | -4.27 | ACOSTA_PROLIFERATION_INDEPENDENT_MYC_TARGETS_DN | MSigDB lists | ACOSTA_PROLIFERATION_INDEPENDENT_MYC_TARGETS_DN | 106 | 25 | 17377 | 2626 |
RHOG,UGP2,RHOC,MCL1,BCL2L1,RIT1,ESYT1,KLF6,RAB5B,CMTM6,NEU1,CREM,GTF2F1,IRF4,SHC1,TNFAIP8,SH3BP1,ARHGEF2,ST3GAL2,MINPP1,USP11,STAT3,CHPF2,CAPN1,LYPLA2 |
| 1.391e-02 | -4.27 | GO_INNATE_IMMUNE_RESPONSE_ACTIVATING_CELL_SURFACE_RECEPTOR_SIGNALING_PATHWAY | MSigDB lists | GO_INNATE_IMMUNE_RESPONSE_ACTIVATING_CELL_SURFACE_RECEPTOR_SIGNALING_PATHWAY | 106 | 25 | 17377 | 2626 |
PDPK1,NRAS,PSMA8,RAF1,PSMB7,PSMA1,CUL1,KRAS,UBE2V1,ICAM2,PRKACA,PSMD9,PSMB9,LYN,PSMB3,PSMC4,PSMD2,PSMA6,PSMD1,RPS27A,TAB2,PSMD8,PSMD3,PSMC1,HRAS |
| 1.395e-02 | -4.27 | protein N-linked glycosylation via asparagine | biological process | GO:0018279 | 45 | 13 | 17256 | 2622 |
RPN1,MAGT1,DDOST,DPM1,STT3A,DAD1,FUT8,ST3GAL2,RPN2,SYVN1,OSTC,LMAN1,MCFD2 |
| 1.395e-02 | -4.27 | cellular response to amino acid starvation | biological process | GO:0034198 | 45 | 13 | 17256 | 2622 |
LARS,MIOS,DAP,WDR59,RRAGC,EIF2AK4,MAP3K5,BECN1,MAPK1,SH3GLB1,SEH1L,FAS,MAPK3 |
| 1.395e-02 | -4.27 | GSE9946_LISTERIA_INF_MATURE_VS_PROSTAGLANDINE2_TREATED_MATURE_DC_UP | MSigDB lists | GSE9946_LISTERIA_INF_MATURE_VS_PROSTAGLANDINE2_TREATED_MATURE_DC_UP | 122 | 28 | 17377 | 2626 |
NCOR2,PPP1R37,NF1,NET1,USP42,TRAK1,LNX2,CBFA2T2,HAUS2,FAS,SH3BP5,MOSPD3,INF2,HGS,TRIM26,EIF2S2,GATC,INPP5A,HIPK2,ZCCHC2,PML,ATP6V0A2,TRIM52,MINPP1,SLC12A2,STAT3,F2R,ATP6V0D1 |
| 1.398e-02 | -4.27 | EXOSC9 (exosome component 9) | protein interactions | 5393 | 56 | 16 | 17029 | 2761 |
EXOSC6,TRIP12,SUMO2,TKT,CUL3,CSNK2A1,EXOSC9,UBE2I,MPG,DDX39A,CAND1,PSMA6,EXOSC7,EXOSC1,CHMP4B,YBX1 |
| 1.398e-02 | -4.27 | RUNX2 (runt related transcription factor 2) | protein interactions | 860 | 56 | 16 | 17029 | 2761 |
HIVEP3,CCNB1,CBFB,ETS1,XRCC5,UBTF,MAP3K4,RB1,SMAD2,AXIN1,HDAC7,PML,SMAD1,SMURF1,STAT3,DVL2 |
| 1.398e-02 | -4.27 | COX4I1 (cytochrome c oxidase subunit 4I1) | protein interactions | 1327 | 56 | 16 | 17029 | 2761 |
SDHB,COA3,NDUFA2,DDOST,MAGT1,TMBIM4,PHB2,VDAC2,COX5A,BCAP29,CISD2,CORO1A,VDAC1,BCAP31,APP,NDUFS4 |
| 1.398e-02 | -4.27 | PPHLN1 (periphilin 1) | protein interactions | 51535 | 56 | 16 | 17029 | 2761 |
CCDC57,TOMM20,MPHOSPH8,CLK3,CENPJ,SEPT8,BCLAF1,BRCA1,BCL2L1,TP53BP2,METTL3,MATR3,APP,IFI16,SRPK2,CDC37 |
| 1.398e-02 | -4.27 | EIF3K (eukaryotic translation initiation factor 3 subunit K) | protein interactions | 27335 | 56 | 16 | 17029 | 2761 |
PA2G4,EIF3L,CYLD,EIF3D,RPS10,UTP15,YBX1,EIF2A,EIF1B,CD81,RPS26,EIF3G,DYNC1LI2,EIF3H,IFI16,EIF3A |
| 1.398e-02 | -4.27 | ASCC2 (activating signal cointegrator 1 complex subunit 2) | protein interactions | 84164 | 56 | 16 | 17029 | 2761 |
POLA2,DEAF1,IMMT,CSRP1,SNRPB,OLA1,MYH9,GFER,CUTC,RPA1,TBC1D17,RPLP1,SMURF1,EEF1D,FAF1,NIPSNAP1 |
| 1.408e-02 | -4.26 | CTTNBP2NL (CTTNBP2 N-terminal like) | protein interactions | 55917 | 38 | 12 | 17029 | 2761 |
ANKRD28,MOB4,PPP2CA,FGFR1OP,HGS,PDCD10,STRIP1,DYNLL1,STRN4,RUFY3,ZRANB1,NIPSNAP1 |
| 1.408e-02 | -4.26 | MRPS24 (mitochondrial ribosomal protein S24) | protein interactions | 64951 | 38 | 12 | 17029 | 2761 |
DDX56,RBM42,MRPS15,KBTBD7,RPL6,MRPS27,TRMT10B,ARMC8,ZC3H3,APP,HAUS2,CCDC59 |
| 1.408e-02 | -4.26 | BEND7 (BEN domain containing 7) | protein interactions | 222389 | 38 | 12 | 17029 | 2761 |
LYAR,PPP1R37,ZCCHC10,DGCR8,MFAP1,PPIG,CDCA7L,USP20,EAF2,NKAPD1,PLEKHF2,BYSL |
| 1.408e-02 | -4.26 | MRPS25 (mitochondrial ribosomal protein S25) | protein interactions | 64432 | 38 | 12 | 17029 | 2761 |
NOL12,DDX56,PCNA,HNRNPAB,MRPS15,GRSF1,MRPS27,DUSP11,KIFAP3,TRMT10B,ZC3H3,CAND1 |
| 1.409e-02 | -4.26 | TRIM27 (tripartite motif containing 27) | protein interactions | 5987 | 314 | 66 | 17029 | 2761 |
USP7,IER2,UBE2E2,RAB11B,WDYHV1,TRIM11,EIF3D,ZFYVE21,UBE2Z,UBE2I,RCOR3,MBD4,RBM23,MDM2,NEK6,SIAH1,UCHL5,JOSD1,SPATC1L,DNMT1,PPP1R18,RBX1,EID1,RNF25,MTMR6,CDC23,MBD3,CHCHD3,SPATA2,C1orf109,UHRF2,TRIM32,USP11,TRAF5,UBE2D3,KRBA1,TWNK,BABAM1,PRKAA1,RACGAP1,ZNF79,HMG20A,VPS25,GFM2,NEIL2,MAD2L2,GTF2F1,MAT2B,RB1,MBD2,XPA,MRPL40,MVP,FBXL19,MEMO1,PSMA1,SNRPA,PSMB3,KPNA1,FAM110A,PIAS2,YJU2,PML,AEN,NDE1,BYSL |
| 1.412e-02 | -4.26 | - | gene3d domains | 2.30.130.10 | 4 | 3 | 8148 | 1295 |
NIP7,EIF2D,MCTS1 |
| 1.412e-02 | -4.26 | - | gene3d domains | 2.40.160.10 | 4 | 3 | 8148 | 1295 |
TOMM40,VDAC1,VDAC2 |
| 1.412e-02 | -4.26 | - | gene3d domains | 3.40.50.261 | 4 | 3 | 8148 | 1295 |
SUCLG2,SUCLG1,ACLY |
| 1.412e-02 | -4.26 | - | gene3d domains | 3.30.420.210 | 4 | 3 | 8148 | 1295 |
UBXN2A,UBXN2B,NSFL1C |
| 1.417e-02 | -4.26 | TSG101 (tumor susceptibility 101) | protein interactions | 7251 | 160 | 37 | 17029 | 2761 |
PDCD6IP,CDS2,EWSR1,SCAMP3,GGA1,GMCL1,DNAJB1,WDR5,UBE2I,SEC16A,BIRC2,PABPC4,MDM2,VASP,DPYSL2,YBX1,TFG,LRSAM1,DNMT1,PABPC1,AATF,RAB7A,AACS,UHRF1BP1,ADRB2,DAPK3,TRIM47,HGS,UPF1,SEC23IP,RAD18,CEP55,ARRDC1,CHMP4B,STK11,ROCK1,TATDN1 |
| 1.417e-02 | -4.26 | The role of Nef in HIV-1 replication and disease pathogenesis | REACTOME pathways | R-HSA-164952 | 29 | 10 | 10287 | 1696 |
ELMO1,RAC1,AP1M1,AP1S1,AP2B1,PACS1,ARF1,AP1B1,AP2S1,HLA-A |
| 1.419e-02 | -4.26 | GAN (gigaxonin) | protein interactions | 8139 | 207 | 46 | 17029 | 2761 |
RPS2,MRPL39,EIF3D,THRAP3,PLXNA1,PABPC4,DST,SPINDOC,DLG5,ARHGEF1,TENM3,MAST2,CARMIL1,PABPC1,HNRNPM,SPTAN1,CCT2,EIF3L,RBX1,RPS10,HNRNPF,CUL3,RPL8,WIPF1,ARHGEF12,BCLAF1,MAP4K3,PLEC,SLC25A5,KIF11,CCT8,RPS9,RPSA,EIF3A,CIP2A,PRDX1,ZMYM3,DNAJC10,RPS27A,STK38,MYO18A,H2AFX,VCPIP1,FAM126A,WDR76,TUBB |
| 1.422e-02 | -4.25 | GO_PHAGOCYTIC_VESICLE_MEMBRANE | MSigDB lists | GO_PHAGOCYTIC_VESICLE_MEMBRANE | 55 | 15 | 17377 | 2626 |
HLA-B,ATP6V0B,RAB8A,RAB11B,HLA-E,RAB7A,RAB23,ATP6V0A1,ATP6V0A2,ATP6V0C,CORO1A,RAB22A,ATP6V0E1,ATP6V0D1,HLA-A |
| 1.422e-02 | -4.25 | UBIQUITIN_CONJUGAT_2 | prosite domains | PS50127 | 39 | 11 | 12060 | 1670 |
UBE2D3,UBE2E2,UBE2Q2,UBE2Q1,UBE2Z,UBE2V1,KRAS,UBE2I,UBE2C,UBE2M,UBE2QL1 |
| 1.424e-02 | -4.25 | human chr12q13.3 | chromosome location | human chr12q13.3 | 56 | 12 | 26185 | 2809 |
BAZ2A,STAT6,DCTN2,NACA,NABP2,CS,PIP4K2C,TIMELESS,MBD6,ATP5F1B,SPRYD4,PRIM1 |
| 1.425e-02 | -4.25 | NS-carcinoma | COSMIC cancer mutations | NS-carcinoma | 46 | 13 | 17385 | 2587 |
NRAS,CDC42,NEK6,PTEN,SF3B1,AXIN1,MAP4K4,KRAS,CHEK2,BRCA1,CDK2,MAP2K2,HRAS |
| 1.425e-02 | -4.25 | peritoneum-mesothelioma | COSMIC cancer mutations | peritoneum-mesothelioma | 46 | 13 | 17385 | 2587 |
GNAS,FGFR3,RB1,NRAS,PTEN,VHL,PTPN11,STK11,KRAS,BRCA1,SMAD4,HRAS,CDKN2A |
| 1.429e-02 | -4.25 | GSE17721_CTRL_VS_PAM3CSK4_24H_BMDC_UP | MSigDB lists | GSE17721_CTRL_VS_PAM3CSK4_24H_BMDC_UP | 188 | 40 | 17377 | 2626 |
LZTR1,ADD1,MRPS15,PIGQ,GSPT2,MEF2A,LANCL1,XPR1,CAPN2,SH3BP1,IL6ST,CDC25B,MRPL48,CLTB,TMEM14C,RPL35,SNX2,ASPM,RAB7A,OXR1,RPL6,DNAJC9,ANAPC2,NFATC2IP,SOX4,RPL27A,ARPC1A,MAPK3,RXRB,ANKRD10,MKNK1,GALNT2,PDLIM1,RNF38,QRSL1,FAU,CCNB2,YWHAH,IGBP1,MYL12B |
| 1.429e-02 | -4.25 | GSE22025_UNTREATED_VS_PROGESTERONE_TREATED_CD4_TCELL_DN | MSigDB lists | GSE22025_UNTREATED_VS_PROGESTERONE_TREATED_CD4_TCELL_DN | 188 | 40 | 17377 | 2626 |
WASF2,CTDP1,IER2,NQO1,CHERP,GADD45G,CREBL2,GGPS1,PPP1R16B,GIT2,ZER1,NFATC3,MLX,GOT2,ATP6V0A2,NDUFS8,TP53BP2,MINPP1,PLCL2,GPX4,TIMP2,ELL2,SREK1,BICD2,CBFB,DDX39A,TARS,CLNS1A,SRSF1,DAP3,UAP1,AXIN1,NCLN,PDXK,RRS1,H3F3A,LTA4H,PITRM1,YWHAH,DDB1 |
| 1.429e-02 | -4.25 | GSE20715_WT_VS_TLR4_KO_6H_OZONE_LUNG_UP | MSigDB lists | GSE20715_WT_VS_TLR4_KO_6H_OZONE_LUNG_UP | 188 | 40 | 17377 | 2626 |
SEPHS2,UBE2D3,OTUD5,TMED7,PLXNC1,MRPL42,RRP15,ANXA6,MDH2,GPR89A,RRM1,MYH9,EIF2AK4,B4GALT4,PSEN1,MAPK14,MYEF2,UBLCP1,TMCC3,FANCL,CTSS,ADD3,KLHL20,BCL2,SLC38A10,SGCB,STAU1,KAT2A,PRKAR1B,PSMB7,MTMR6,NFATC2IP,ICMT,TWSG1,PSMD8,H2AFX,COX5A,NCOA1,SMAD1,GPR89B |
| 1.429e-02 | -4.25 | GSE17721_POLYIC_VS_GARDIQUIMOD_16H_BMDC_UP | MSigDB lists | GSE17721_POLYIC_VS_GARDIQUIMOD_16H_BMDC_UP | 188 | 40 | 17377 | 2626 |
TRIM41,GOLPH3L,PHF23,SRGN,C19orf25,NKD2,RRAGC,PXMP2,POMP,IL21R,CMTM6,FANCI,TMCC3,PRNP,RBM17,CRKL,MBD2,RRBP1,AP1M1,FAM89B,H2AFY,MDFIC,MVP,SGCB,TIPARP,PACS2,MORC3,ARHGAP17,NET1,DENND4C,PFKFB3,RBM25,STAT6,BBX,DUSP11,NCOA1,NRBP1,ATMIN,ANXA11,RNF114 |
| 1.429e-02 | -4.25 | GSE22229_RENAL_TRANSPLANT_IMMUNOSUPP_THERAPY_VS_HEALTHY_PBMC_UP | MSigDB lists | GSE22229_RENAL_TRANSPLANT_IMMUNOSUPP_THERAPY_VS_HEALTHY_PBMC_UP | 188 | 40 | 17377 | 2626 |
KARS,PRPF38B,GMFG,MOGS,GMCL1,SLC35B1,ARF1,NUDT19,FANCL,DDX56,EIF2S2,SNUPN,RALB,H2AFY,OSTF1,MRPL21,SMARCE1,GINS1,NAGPA,TDP1,CCT2,STAU1,NASP,PRIM2,LAP3,ABCF2,KIAA0930,DNAJC9,LNX2,PSMC4,TMEM184C,TMED10,CERS6,NFIL3,SLC16A1,SRSF3,PLOD3,PGAM1,LTA4H,SVIP |
| 1.429e-02 | -4.25 | GSE1432_6H_VS_24H_IFNG_MICROGLIA_UP | MSigDB lists | GSE1432_6H_VS_24H_IFNG_MICROGLIA_UP | 188 | 40 | 17377 | 2626 |
RHOG,TRIP12,DCTN2,SNX15,SDC2,FLOT1,CBLL1,PMF1,SLC25A44,CDIPT,EXT2,LMNA,RAD23A,DNAJC8,SAR1A,PPP4R1,TNPO3,BCAP29,TARDBP,MAST2,SPTSSA,STAT3,CGGBP1,HTRA2,CDKN2AIP,STAU1,KIAA0040,AMD1,EMP3,CADM1,PITPNB,RAB5B,MARK2,TARS,VEZF1,CDC27,UEVLD,YWHAZ,ATP6V1C1,HRAS |
| 1.429e-02 | -4.25 | GSE9316_CD4_TCELL_BALBC_VS_TH17_ENRI_CD4_TCELL_SKG_PMA_IONO_STIM_FR4NEG_DN | MSigDB lists | GSE9316_CD4_TCELL_BALBC_VS_TH17_ENRI_CD4_TCELL_SKG_PMA_IONO_STIM_FR4NEG_DN | 188 | 40 | 17377 | 2626 |
TRIM41,TOMM20,PLXNC1,C16orf87,NIPA2,PAWR,OAT,ZADH2,ETS1,CDC73,FBXO22,MAN1A1,CFLAR,NFATC3,DAPK1,PTGES3,NAA35,MTPN,ADCY7,EBAG9,POU2AF1,FAM49B,TIMMDC1,SUGP2,LACTB,RNPS1,WIPF1,MCL1,SERP1,SRSF1,TSC1,HSPA4,GRIPAP1,PROSER1,MAPK6,IARS2,DDX5,YY1,LTA4H,ALS2 |
| 1.429e-02 | -4.25 | GSE11961_FOLLICULAR_BCELL_VS_GERMINAL_CENTER_BCELL_DAY40_DN | MSigDB lists | GSE11961_FOLLICULAR_BCELL_VS_GERMINAL_CENTER_BCELL_DAY40_DN | 188 | 40 | 17377 | 2626 |
MRPL42,GNPDA1,DYNLL1,PIGQ,ANKH,CIB1,CBLL1,TBC1D13,MYO9B,MAPK14,GIT2,MEAF6,IRF4,SNRNP25,FBXO7,PPP1R12C,ARL6IP1,BCL2,MCMBP,GM2A,TRIM14,NASP,PGGT1B,KIAA0040,PPP1R21,KCTD20,WDHD1,GALNT7,HAUS8,EPB41,CHCHD3,TAF2,CORO1C,STK38,PPM1G,SCARB1,AKNA,NDE1,IDH3B,PDCD2L |
| 1.429e-02 | -4.25 | GSE40666_WT_VS_STAT4_KO_CD8_TCELL_WITH_IFNA_STIM_90MIN_DN | MSigDB lists | GSE40666_WT_VS_STAT4_KO_CD8_TCELL_WITH_IFNA_STIM_90MIN_DN | 188 | 40 | 17377 | 2626 |
SRM,HIVEP3,UBE2E2,PARP12,CLSPN,SCAMP3,SRGN,MAGED1,FLOT1,SLC29A1,FKBP2,PSEN1,LCLAT1,RAP1A,NEK6,MCM5,SSBP3,RAB4A,SEPT11,F2R,PPA1,PLK3,TRAFD1,DCTD,UBE2V1,SLC17A5,VDAC1,BBS12,C1orf122,PTPRF,BOLA3,PEX5,FAM3C,LRPPRC,CTSA,ATF6,SCARB1,PGAM1,RTN3,CDKN2A |
| 1.429e-02 | -4.25 | PROVENZANI_METASTASIS_DN | MSigDB lists | PROVENZANI_METASTASIS_DN | 133 | 30 | 17377 | 2626 |
CLPTM1,TXNL1,FTL,DNAJC2,ERCC1,TIMP2,ANXA6,RBM42,SLC2A1,NOTCH2,PSMB9,ARPC1A,REEP5,CNOT3,BCAT2,EIF3K,NAPG,PON2,HSPA4,TMED10,CLU,GPI,COPS6,EHD4,PLOD3,PDIA6,GPD1L,UBE2M,AP2S1,FAM171A1 |
| 1.429e-02 | -4.25 | GO_MEIOTIC_CELL_CYCLE_PROCESS | MSigDB lists | GO_MEIOTIC_CELL_CYCLE_PROCESS | 133 | 30 | 17377 | 2626 |
PLK1,ASPM,UBR2,NSUN2,ACTR3,PTTG1,MKI67,TOP3A,TUBGCP5,MYH9,TOP2B,SMC2,TUBGCP2,FBXO5,RAD54B,MASTL,RAD51C,SMC3,KIF18A,GOLGA2,XRCC2,MSH2,XRCC3,CDC25B,CDK2,TERF1,ESPL1,MSH6,RAD51D,SMC4 |
| 1.433e-02 | -4.25 | OSGEP (O-sialoglycoprotein endopeptidase) | protein interactions | 55644 | 75 | 20 | 17029 | 2761 |
TP53RK,PKP4,PPP1R12A,NSUN2,LAGE3,HNRNPF,WDR82,RANGAP1,DNAJA1,EFL1,API5,GLRX3,VPS25,EEF2K,TPD52L2,MBIP,SHC1,NVL,POP7,RPRD1B |
| 1.433e-02 | -4.25 | PFN1 (profilin 1) | protein interactions | 5216 | 75 | 20 | 17029 | 2761 |
COX15,NCK1,CUL3,BRCA1,MCM2,VDAC1,CDC73,ISG15,MAPK3,CAND1,DLG5,AFDN,VASP,UCHL5,DNM2,ACTB,FUS,CDK2,ATF2,CFL1 |
| 1.433e-02 | -4.25 | UBE2B (ubiquitin conjugating enzyme E2 B) | protein interactions | 7320 | 75 | 20 | 17029 | 2761 |
UNK,UBQLN4,UBR2,UBE2V1,KCMF1,BIRC2,SRXN1,MDM2,PCNA,RAD18,PRDX5,CDKN1B,ZRANB2,TTLL12,AHCYL1,UBE2C,IGBP1,SLF1,SSSCA1,NIPSNAP1 |
| 1.435e-02 | -4.24 | TM9SF4 (transmembrane 9 superfamily member 4) | protein interactions | 9777 | 47 | 14 | 17029 | 2761 |
RPAP3,ERMP1,SCAMP3,NSMCE2,CDCA7L,PHF14,ABCF2,SLC25A12,RPN2,RAB1A,H2AFV,ZNF800,S100A6,TMED2 |
| 1.435e-02 | -4.24 | PTPN21 (protein tyrosine phosphatase, non-receptor type 21) | protein interactions | 11099 | 47 | 14 | 17029 | 2761 |
RMND5A,PFDN4,NEK7,DCAF8,TMX3,CSNK2A1,POLR1B,PM20D2,ACAD8,AHCYL1,WDR5,ARMC8,DCAF5,AKAP1 |
| 1.435e-02 | -4.24 | USP33 (ubiquitin specific peptidase 33) | protein interactions | 23032 | 47 | 14 | 17029 | 2761 |
DDX56,PRPF38B,CCP110,RALB,VHL,LPCAT4,PCGF6,USP20,ADRB2,ARRB2,BECN1,USP21,ZFR,KRR1 |
| 1.435e-02 | -4.24 | CNOT9 (CCR4-NOT transcription complex subunit 9) | protein interactions | 9125 | 47 | 14 | 17029 | 2761 |
CNOT9,GPBP1L1,GADD45B,KRAS,CNOT6,RUVBL2,CAPZA2,CNTROB,ATP6V1B2,CNOT6L,CNOT11,TOB1,GIGYF1,CNOT3 |
| 1.435e-02 | -4.24 | PGAM1 (phosphoglycerate mutase 1) | protein interactions | 5223 | 47 | 14 | 17029 | 2761 |
MDM2,PCNA,PKP4,TXN,RAB11B,AKR1B1,GLO1,TAGLN2,NUTF2,PCGF1,RAB11A,SDHA,CLNS1A,DCTN1 |
| 1.435e-02 | -4.24 | MRPL22 (mitochondrial ribosomal protein L22) | protein interactions | 29093 | 47 | 14 | 17029 | 2761 |
MRPL50,MRPL2,RPS2,MRPL9,CYLD,MRPL42,MRPL39,MRPL12,TUFM,LAMTOR3,MPV17,MRPL16,TARDBP,DUSP11 |
| 1.435e-02 | -4.24 | SLC25A13 (solute carrier family 25 member 13) | protein interactions | 10165 | 47 | 14 | 17029 | 2761 |
IMMT,BABAM2,CYLD,PPT1,NEIL3,ZNF746,BABAM1,SLC25A12,XRCC3,ADRB2,CLN3,MCM2,VDAC1,ATF2 |
| 1.435e-02 | -4.24 | TRUB2 (TruB pseudouridine synthase family member 2) | protein interactions | 26995 | 47 | 14 | 17029 | 2761 |
MRPL50,DDX28,RBM42,MRPL39,RBMX,BOLA1,CYCS,ACAD8,PITRM1,ZC3H3,ECH1,GLMP,TIMM50,RCC1L |
| 1.435e-02 | -4.24 | ZBED1 (zinc finger BED-type containing 1) | protein interactions | 9189 | 47 | 14 | 17029 | 2761 |
CREG1,NIP7,UCHL5,MTA2,SUMO2,PRKAA1,C1orf109,PIAS2,PSAP,USP22,ATP6V1B2,UBE2I,MBD3,CSTF1 |
| 1.435e-02 | -4.24 | ANAPC2 (anaphase promoting complex subunit 2) | protein interactions | 29882 | 47 | 14 | 17029 | 2761 |
RB1,MDM2,CDC16,SMAD2,CDC27,PRKDC,C16orf87,PTTG1,ANAPC7,CDC23,UBE2C,ANAPC4,CDC5L,FBXO5 |
| 1.436e-02 | -4.24 | LIANG_HEMATOPOIESIS_STEM_CELL_NUMBER_SMALL_VS_HUGE_UP | MSigDB lists | LIANG_HEMATOPOIESIS_STEM_CELL_NUMBER_SMALL_VS_HUGE_UP | 36 | 11 | 17377 | 2626 |
MAT2B,UBE2D3,APLP2,GCLM,CLCN3,AGRN,GTF3A,PAWR,GAS2,ACADM,LYRM2 |
| 1.436e-02 | -4.24 | CHANGOLKAR_H2AFY_TARGETS_DN | MSigDB lists | CHANGOLKAR_H2AFY_TARGETS_DN | 36 | 11 | 17377 | 2626 |
MPHOSPH8,EIF4A3,TMEM39A,ELL2,GTPBP4,VCPIP1,ATP6V0A2,H2AFY,SECISBP2,USF2,LUC7L2 |
| 1.436e-02 | -4.24 | REACTOME_GAB1_SIGNALOSOME | MSigDB lists | REACTOME_GAB1_SIGNALOSOME | 36 | 11 | 17377 | 2626 |
PDPK1,MDM2,TSC2,PTEN,CSK,AKT2,CDKN1B,AKT1S1,CREB1,FOXO3,MLST8 |
| 1.436e-02 | -4.24 | REACTOME_IRON_UPTAKE_AND_TRANSPORT | MSigDB lists | REACTOME_IRON_UPTAKE_AND_TRANSPORT | 36 | 11 | 17377 | 2626 |
FTL,ATP6V0B,ATP6V1D,ATP6V0A2,ATP6V0C,ATP6V1B2,ATP6V1C1,ATP6V0D1,ATP6V0E1,TFRC,ATP6V1G1 |
| 1.437e-02 | -4.24 | DER_IFN_GAMMA_RESPONSE_UP | MSigDB lists | DER_IFN_GAMMA_RESPONSE_UP | 70 | 18 | 17377 | 2626 |
BAK1,PPP3CA,HLA-E,RHOC,TAP1,CYCS,PSMB9,HLA-A,ISG15,FAS,ATP6V0B,TRIM26,STAT1,HADHB,PML,PPP5C,RBBP4,IFI16 |
| 1.437e-02 | -4.24 | TURASHVILI_BREAST_DUCTAL_CARCINOMA_VS_LOBULAR_NORMAL_UP | MSigDB lists | TURASHVILI_BREAST_DUCTAL_CARCINOMA_VS_LOBULAR_NORMAL_UP | 70 | 18 | 17377 | 2626 |
VOPP1,RRP15,ASPM,DENND1B,RAC1,RACGAP1,NUSAP1,EIF2AK1,ANLN,GLRX3,KCMF1,FANCI,DTL,RAB18,INTS7,RBM34,FUT8,GLCCI1 |
| 1.437e-02 | -4.24 | GO_RNA_POLYMERASE_II_TRANSCRIPTION_FACTOR_COMPLEX | MSigDB lists | GO_RNA_POLYMERASE_II_TRANSCRIPTION_FACTOR_COMPLEX | 101 | 24 | 17377 | 2626 |
TCF12,ERCC1,HNRNPAB,KAT2A,TCF3,EDF1,PRMT2,TRIM28,GTF2F1,TAF2,RB1,SMAD2,MED10,HIPK2,E2F1,TBPL1,TAF5L,TAF12,CREB1,STAT3,TAF6,GTF2H2,SMAD4,CARM1 |
| 1.438e-02 | -4.24 | regulation of chromatin organization | biological process | GO:1902275 | 165 | 36 | 17256 | 2622 |
TRIP12,KMT2E,MECP2,CCNB1,AKAP8,NOC2L,ZNF335,H2AFY,CTR9,BRD7,CHTOP,DNMT1,TGFB1,ZFP64,KAT2A,EID1,KAT7,MIER1,TLK1,WBP2,MKI67,RTF1,BRCA1,KDM3A,TRIM28,IWS1,MAPK3,PAF1,ATAD2,PARG,OGT,UHRF2,KMT2B,RUVBL2,PARP10,SMAD4 |
| 1.439e-02 | -4.24 | HDAC6 (histone deacetylase 6) | protein interactions | 10013 | 255 | 55 | 17029 | 2761 |
DDX58,UBE2D3,POLA2,USP7,MAPRE1,CYLD,ATXN3,DYNLL1,SIRT2,SEC16A,ZNF518A,PCNA,PSMD1,GRK2,CENPJ,KMT5A,BDH1,ETV6,PELO,RAD23B,MSH2,TARDBP,POLR1B,UTP4,MSH6,TIMM50,NASP,UTP15,DNAJA1,PBRM1,ADRB2,OGDH,PKM,VKORC1,MCM2,PDHX,ISG15,MAPK3,ZMYM3,MFN2,XRCC5,GEMIN5,BRMS1,KPNA1,HSPA4,FNTA,PLAA,BIRC5,PML,YWHAZ,ACTB,MAPK1,PFKP,TUBB,PTOV1 |
| 1.439e-02 | -4.24 | GO_CELLULAR_RESPONSE_TO_HYDROGEN_PEROXIDE | MSigDB lists | GO_CELLULAR_RESPONSE_TO_HYDROGEN_PEROXIDE | 60 | 16 | 17377 | 2626 |
PPIF,MDM2,PDCD10,TNFAIP3,NET1,STAT6,PRKAA1,AKR1B1,MAP3K5,PPP5C,KLF6,ETS1,PARK7,RHOB,HDAC2,FAS |
| 1.441e-02 | -4.24 | UIM | prosite domains | PS50330 | 20 | 7 | 12060 | 1670 |
EPN1,HGS,ANKRD13D,ATXN3,ANKIB1,STAM,DNAJB2 |
| 1.441e-02 | -4.24 | LUI_THYROID_CANCER_CLUSTER_3 | MSigDB lists | LUI_THYROID_CANCER_CLUSTER_3 | 27 | 9 | 17377 | 2626 |
EIF3K,RPS2,HINT1,RPL17,PSMD8,ERGIC3,TMEM147,FBL,EIF3G |
| 1.441e-02 | -4.24 | GO_MATURATION_OF_5_8S_RRNA | MSigDB lists | GO_MATURATION_OF_5_8S_RRNA | 27 | 9 | 17377 | 2626 |
NSA2,UTP20,EXOSC7,EXOSC9,ERI3,RRS1,FTSJ3,MAK16,RPSA |
| 1.441e-02 | -4.24 | MODULE_318 | MSigDB lists | MODULE_318 | 27 | 9 | 17377 | 2626 |
RAD51C,CHD3,DHX9,XRCC3,DDX5,CITED2,BLM,RAD51D,XRCC5 |
| 1.441e-02 | -4.24 | GO_SITE_OF_DOUBLE_STRAND_BREAK | MSigDB lists | GO_SITE_OF_DOUBLE_STRAND_BREAK | 27 | 9 | 17377 | 2626 |
RFWD3,RPA2,SMC6,RAD18,ATF2,HELB,RNF169,H2AFX,PRPF19 |
| 1.441e-02 | -4.24 | SIG_IL4RECEPTOR_IN_B_LYPHOCYTES | MSigDB lists | SIG_IL4RECEPTOR_IN_B_LYPHOCYTES | 27 | 9 | 17377 | 2626 |
PDPK1,SHC1,JAK1,AKT2,STAT6,RAF1,BCL2,MAPK1,MAPK3 |
| 1.441e-02 | -4.24 | GNF2_ATM | MSigDB lists | GNF2_ATM | 27 | 9 | 17377 | 2626 |
HECA,ACAP1,OGT,BTN3A1,PPWD1,PIK3IP1,SYNRG,RAPGEF6,DEF6 |
| 1.441e-02 | -4.24 | MODULE_226 | MSigDB lists | MODULE_226 | 27 | 9 | 17377 | 2626 |
PPP2CA,RFC3,ARF5,DYNLL1,PPP6C,GMFB,PPP1R11,PRPSAP1,ARF4 |
| 1.443e-02 | -4.24 | small_intestine | COSMIC cancer mutations | small_intestine | 254 | 51 | 17385 | 2587 |
HSPH1,AGRN,SF3B1,KIAA0232,SRGN,HAUS4,ZNRF3,NOTCH2,ABHD14A,ABHD16A,CDKN2C,ANKRD26,FGFR3,NDUFV1,VMP1,NVL,MSH2,PTPN11,PDS5B,ARHGEF2,TAF5L,MICAL3,DCTN1,TRAPPC9,NRAS,TNFAIP3,POLR2G,VHL,GTPBP4,CRNKL1,PARP4,KRAS,MEN1,ICMT,MACF1,DHX15,EPB41,GNAS,ATP6V1D,DSN1,CDC27,BIRC5,CAPN7,LRPPRC,STK11,SMAD1,SMAD4,ACSF2,RNF139,HRAS,CDKN2A |
| 1.443e-02 | -4.24 | KEGG_P53_SIGNALING_PATHWAY | MSigDB lists | KEGG_P53_SIGNALING_PATHWAY | 65 | 17 | 17377 | 2626 |
TSC2,GADD45G,RRM2,CYCS,CCNB1,FAS,MDM2,SIAH1,PTEN,GADD45B,EI24,GTSE1,CHEK2,CCNB2,CDK2,ZMAT3,CDKN2A |
| 1.443e-02 | -4.24 | GO_ER_TO_GOLGI_TRANSPORT_VESICLE | MSigDB lists | GO_ER_TO_GOLGI_TRANSPORT_VESICLE | 65 | 17 | 17377 | 2626 |
TMED7,USO1,HLA-E,VTI1A,MCFD2,APP,HLA-A,CD59,SEC31A,HLA-B,SEC23IP,GOLGA2,SCAP,TMED10,SEC24C,LMAN1,TMED2 |
| 1.443e-02 | -4.24 | V$E2F_01 | MSigDB lists | V$E2F_01 | 65 | 17 | 17377 | 2626 |
CSDE1,YTHDC1,RNF121,PCNA,NASP,PRKDC,AMD1,H2AFX,RMI2,E2F1,E2F3,KHSRP,AP1S1,MCM2,DNMT1,ARID4A,SMC4 |
| 1.445e-02 | -4.24 | GSE9037_CTRL_VS_LPS_4H_STIM_IRAK4_KO_BMDM_UP | MSigDB lists | GSE9037_CTRL_VS_LPS_4H_STIM_IRAK4_KO_BMDM_UP | 177 | 38 | 17377 | 2626 |
NAT14,PTMS,CORO7,DCAF15,DAP,ENSA,MEF2A,GMCL1,AKT1S1,BCL2L1,ITGB5,MRPL19,TFAP4,LPIN2,FAM89B,TECR,CNNM3,CLN6,CTDSP2,SNX8,MLEC,TRIM8,ANKRD37,OXR1,LDB1,DNAJC9,PTTG1IP,MCFD2,PDE3B,EPB41,MAN2A2,PWWP2B,SGSH,PALB2,MDH1,SCARB1,CHEK2,ACSF2 |
| 1.445e-02 | -4.24 | GSE46606_UNSTIM_VS_CD40L_IL2_IL5_DAY1_STIMULATED_BCELL_UP | MSigDB lists | GSE46606_UNSTIM_VS_CD40L_IL2_IL5_DAY1_STIMULATED_BCELL_UP | 177 | 38 | 17377 | 2626 |
LETMD1,TIA1,TOP2B,SYNRG,RCOR3,STAM,HMG20A,MAT2B,CDKN2C,TNS3,ADD3,PTEN,SIAH1,PHTF1,AFF1,ZNF226,CTDSP2,PCBP2,CLCN3,SGCE,ERMP1,GALC,ZNF512,NOA1,EHMT1,KIF15,LNX2,C14orf132,PDE3B,CAT,CCDC14,STAT1,DTX4,RBPJ,CCNB2,GLCCI1,UNC13C,TOB1 |
| 1.445e-02 | -4.24 | GSE11961_MARGINAL_ZONE_BCELL_VS_PLASMA_CELL_DAY7_DN | MSigDB lists | GSE11961_MARGINAL_ZONE_BCELL_VS_PLASMA_CELL_DAY7_DN | 177 | 38 | 17377 | 2626 |
GALK1,GMFG,C1orf112,CDCA3,ZNRF3,ORC1,C19orf48,RSAD1,NFATC3,PSMD1,VMP1,DNAAF2,DUT,AKAP8,GTSE1,INTS12,ANP32A,CNOT6L,TIMM50,TXNL1,VOPP1,TTPAL,NTPCR,DDX24,PRIM2,PLEC,PDE3B,NCDN,RAD54B,PRIM1,XRCC5,NUCB1,PDCD6,ESPL1,TSEN15,TSPAN5,ZNF598,DEF6 |
| 1.445e-02 | -4.24 | GSE6674_CPG_VS_PL2_3_STIM_BCELL_UP | MSigDB lists | GSE6674_CPG_VS_PL2_3_STIM_BCELL_UP | 177 | 38 | 17377 | 2626 |
TMEM106C,C19orf53,TMBIM4,UROD,SLC25A12,ADCK5,MXD4,PRKACA,TCF19,RPAIN,FAM192A,OIP5,DECR1,USF1,CNPY4,NDUFB9,RNASEH2A,ELOF1,TIMP2,NQO2,PPP1R21,TMEM216,HTATIP2,SEPT8,COMMD4,GINS4,SUGP1,TXNDC16,DSN1,TOMM6,MRPL27,MPV17,VCPIP1,MDH1,TMEM101,CHEK2,MZT2B,HIGD2A |
| 1.446e-02 | -4.24 | central_nervous_system-brain-glioma-ependymoma | COSMIC cancer mutations | central_nervous_system-brain-glioma-ependymoma | 23 | 8 | 17385 | 2587 |
NF1,PTEN,VHL,CIC,PTPN11,H3F3A,CDKN2A,FUBP1 |
| 1.448e-02 | -4.23 | transcriptional activator activity, RNA polymerase II transcription factor binding | molecular function | GO:0001190 | 64 | 17 | 17224 | 2647 |
POU3F2,POU2AF1,DHX9,WBP2,SMARCA4,MEF2A,BRCA1,SOX4,TRIM28,WWP2,HIPK2,ARNTL,PITX1,NCOA1,CREB1,CITED2,CARM1 |
| 1.449e-02 | -4.23 | PANGAS_TUMOR_SUPPRESSION_BY_SMAD1_AND_SMAD5_DN | MSigDB lists | PANGAS_TUMOR_SUPPRESSION_BY_SMAD1_AND_SMAD5_DN | 144 | 32 | 17377 | 2626 |
SRSF11,CORO7,MAX,MAPRE2,FAM49B,TMEM39A,ACSL3,NIPA2,ADCK5,SDF2L1,CNTROB,BORA,ARL5B,PAIP1,SUPT16H,GSTK1,DNAJC10,ATP1A1,RBMX,EFCAB11,ARL6IP1,SLC16A1,PARL,YBX1,HMGB2,ANAPC7,CNOT6,RBBP4,LPCAT1,LRP8,TMX1,FDFT1 |
| 1.449e-02 | -4.23 | NIKOLSKY_BREAST_CANCER_8Q23_Q24_AMPLICON | MSigDB lists | NIKOLSKY_BREAST_CANCER_8Q23_Q24_AMPLICON | 144 | 32 | 17377 | 2626 |
WDYHV1,PTP4A3,ADCK5,COMMD5,ZNF696,LRRC14,CYHR1,FBXL6,NDUFB9,CYC1,TOP1MT,ZC3H3,EEF1D,EBAG9,PHF20L1,TRAPPC9,TSTA3,TIGD5,RPL8,PLEC,LY6E,EIF3H,DERL1,TAF2,ATAD2,ZHX1,TONSL,NSMCE2,TATDN1,MRPL13,PARP10,RNF139 |
| 1.451e-02 | -4.23 | Sec61 complex | KEGG pathways | hsa_M00401 | 4 | 3 | 7161 | 1149 |
SEC61B,SEC61A1,SEC61G |
| 1.451e-02 | -4.23 | DNA polymerase alpha / primase complex | KEGG pathways | M00261 | 4 | 3 | 7161 | 1149 |
POLA2,PRIM2,PRIM1 |
| 1.451e-02 | -4.23 | DNA polymerase alpha / primase complex | KEGG pathways | hsa_M00261 | 4 | 3 | 7161 | 1149 |
POLA2,PRIM2,PRIM1 |
| 1.451e-02 | -4.23 | Sec61 complex | KEGG pathways | M00401 | 4 | 3 | 7161 | 1149 |
SEC61B,SEC61A1,SEC61G |
| 1.452e-02 | -4.23 | TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain | REACTOME pathways | R-HSA-6804115 | 21 | 8 | 10287 | 1696 |
CNOT9,PLK3,CENPJ,BTG2,CNOT6,CNOT6L,CNOT11,CNOT3 |
| 1.455e-02 | -4.23 | GSE18281_CORTEX_VS_MEDULLA_THYMUS_UP | MSigDB lists | GSE18281_CORTEX_VS_MEDULLA_THYMUS_UP | 166 | 36 | 17377 | 2626 |
UBL3,ANKRD27,EWSR1,NUP188,FOXM1,PRKCSH,BABAM1,YTHDC2,CUL1,ARF1,COMMD5,SLC12A9,GIT2,TFRC,MBD4,EXOSC7,SRSF4,TRA2B,ARL5A,HNRNPM,MSH6,RB1CC1,DCAF8,NEK7,PPP1R21,ZFAND5,EML4,ASF1B,IWS1,DDX17,HGS,SEC61A1,SLC38A7,ZSWIM3,BRD9,PTDSS1 |
| 1.455e-02 | -4.23 | GSE21927_SPLENIC_C26GM_TUMOROUS_VS_4T1_TUMOR_MONOCYTES_DN | MSigDB lists | GSE21927_SPLENIC_C26GM_TUMOROUS_VS_4T1_TUMOR_MONOCYTES_DN | 166 | 36 | 17377 | 2626 |
DDX58,MAGEH1,PLXNC1,B4GALT5,GSPT2,GLUD1,SLC25A43,BIRC2,SLC25A37,PRKD3,GART,MED10,INTS7,UTP18,TIMELESS,DDX31,LONRF3,TSTA3,LAP3,PBK,NET1,TUBGCP5,PITPNB,MAK16,ARHGAP15,TMEM184C,TMEM41A,DAP3,SERTAD2,DTX4,WDR7,COX5A,FBXL3,RPS6KC1,LTA4H,ZBTB24 |
| 1.456e-02 | -4.23 | Abortive elongation of HIV-1 transcript in the absence of Tat | REACTOME pathways | R-HSA-167242 | 25 | 9 | 10287 | 1696 |
CTDP1,POLR2I,POLR2J,POLR2G,POLR2L,POLR2K,POLR2D,POLR2A,GTF2F1 |
| 1.456e-02 | -4.23 | Nuclear Events (kinase and transcription factor activation) | REACTOME pathways | R-HSA-198725 | 25 | 9 | 10287 | 1696 |
PPP2CA,MEF2A,CREB1,ELK1,DUSP3,MAPK1,MAPK14,RPS6KA1,MAPK3 |
| 1.456e-02 | -4.23 | Deadenylation of mRNA | REACTOME pathways | R-HSA-429947 | 25 | 9 | 10287 | 1696 |
CNOT9,EIF4A3,CNOT6,CNOT6L,PARN,CNOT11,PABPC1,CNOT3,PAIP1 |
| 1.456e-02 | -4.23 | Constitutive Signaling by AKT1 E17K in Cancer | REACTOME pathways | R-HSA-5674400 | 25 | 9 | 10287 | 1696 |
PDPK1,MDM2,TSC2,AKT2,CDKN1B,AKT1S1,CREB1,FOXO3,MLST8 |
| 1.456e-02 | -4.23 | GSE14000_TRANSLATED_RNA_VS_MRNA_4H_LPS_DC_DN | MSigDB lists | GSE14000_TRANSLATED_RNA_VS_MRNA_4H_LPS_DC_DN | 155 | 34 | 17377 | 2626 |
RHOG,DAP,RAC1,C19orf25,NENF,SLC35B1,HAUS2,RPL23A,UBXN2A,RAP1A,MZT2A,UBE2Q2,NDUFA2,TMED2,RPP25,GUK1,POLR2D,TMEM147,PRMT2,NDUFB1,H2AFV,SERP1,RHEB,RPL36,HMGN2,TMEM184C,AMZ2,GOLGA7,SERF2,RPS14,NDUFA11,TBPL1,RPLP1,STARD3NL |
| 1.456e-02 | -4.23 | response to dsRNA | biological process | GO:0043331 | 85 | 21 | 17256 | 2622 |
DDX58,CGAS,AGO2,DHX9,FLOT1,IRF3,PRKRA,METTL3,SRRT,TUT4,MAPK3,HNRNPA2B1,SMAD2,RALB,DGCR8,ZC3H7B,PQBP1,TICAM1,MAVS,SMAD1,MAPK1 |
| 1.460e-02 | -4.23 | NIK-->noncanonical NF-kB signaling | REACTOME pathways | R-HSA-5676590 | 60 | 17 | 10287 | 1696 |
PSMA8,PSMB7,PSMA1,CUL1,PSMB9,PSMD9,PSMB3,PSMC4,PSMD2,PSMA6,PSMD1,RPS27A,PSMD3,PSMD8,MAP3K14,UBE2M,PSMC1 |
| 1.467e-02 | -4.22 | acute_leukaemia_of_ambiguous_lineage | COSMIC cancer mutations | acute_leukaemia_of_ambiguous_lineage | 61 | 16 | 17385 | 2587 |
CDKN2C,PCM1,EWSR1,DNMT3A,NRAS,JAK1,PTEN,SF3B1,PTPN11,KRAS,NOTCH2,ARID1A,STAT3,HRAS,CDKN2A,PHF6 |
| 1.467e-02 | -4.22 | haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-acute_leukaemia_of_ambiguous_lineage | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-acute_leukaemia_of_ambiguous_lineage | 61 | 16 | 17385 | 2587 |
CDKN2C,PCM1,EWSR1,DNMT3A,NRAS,JAK1,PTEN,SF3B1,PTPN11,KRAS,NOTCH2,ARID1A,STAT3,HRAS,CDKN2A,PHF6 |
| 1.471e-02 | -4.22 | EPHB-mediated forward signaling | REACTOME pathways | R-HSA-3928662 | 42 | 13 | 10287 | 1696 |
RHOA,CDC42,ARPC5,LIMK1,ACTR3,RAC1,SDC2,ACTB,ROCK1,ARPC1A,LYN,HRAS,CFL1 |
| 1.472e-02 | -4.22 | OPTN (optineurin) | protein interactions | 10133 | 80 | 21 | 17029 | 2761 |
RAB14,CYLD,RAB11B,KCTD17,LNX2,GTF3A,CDC23,DAZAP2,MAP1LC3B,RAB11A,TFRC,OPTN,GNAS,RAB8A,TBC1D17,BABAM2,YWHAZ,WIPI2,YWHAH,SLF2,RAB3IL1 |
| 1.472e-02 | -4.22 | Nef mediated downregulation of MHC class I complex cell surface expression | REACTOME pathways | R-HSA-164940 | 10 | 5 | 10287 | 1696 |
AP1S1,PACS1,AP1B1,HLA-A,AP1M1 |
| 1.472e-02 | -4.22 | MASTL Facilitates Mitotic Progression | REACTOME pathways | R-HSA-2465910 | 10 | 5 | 10287 | 1696 |
PPP2CA,CCNB1,PPP2R2D,MASTL,ENSA |
| 1.473e-02 | -4.22 | B_cell_lymphoma_unspecified | COSMIC cancer mutations | B_cell_lymphoma_unspecified | 32 | 10 | 17385 | 2587 |
CDKN2C,NRAS,PTEN,SF3B1,ATIC,KRAS,NOTCH2,STAT3,HRAS,CDKN2A |
| 1.477e-02 | -4.22 | GO_NEGATIVE_REGULATION_OF_TRANSCRIPTION_FROM_RNA_POLYMERASE_II_PROMOTER | MSigDB lists | GO_NEGATIVE_REGULATION_OF_TRANSCRIPTION_FROM_RNA_POLYMERASE_II_PROMOTER | 719 | 130 | 17377 | 2626 |
ZNF496,TXN,TSC22D3,SIRT2,UBE2I,GLIS2,JAZF1,ETV6,NOC2L,FNIP2,CRY2,DNMT1,RYBP,PLK3,PLK1,SP3,KLF10,NCK1,GABPA,VHL,EHMT1,EZR,DDX20,AURKB,PAF1,BRMS1,HHEX,SMAD2,RPS27A,RPS14,AXIN1,ZNF268,BEND6,HDAC2,ZNF564,UBE2D3,NACA,CTCF,MEF2A,PSEN1,CDC73,RB1,NFATC3,MLX,KLF16,HDAC7,MBD2,PHF14,ZNF746,TIMELESS,CTR9,ZNF189,ETV3,CIC,ZMYND11,MTA2,RTF1,ARID1A,ZNF174,ETS2,NFIL3,ZFP90,YY1,N4BP2L2,MBD1,ZNF296,DNMT3A,FOXM1,SUZ12,WDTC1,SMARCA4,IRF3,RCOR3,DUSP22,MXD1,SAP130,HNRNPA2B1,MDM2,SP100,ATF2,STRAP,CGGBP1,SAP30,MOSPD1,RLIM,EID1,ERF,DRAP1,BTG2,CUL3,PCGF6,NFATC2,MBD3,TRIM28,CHCHD3,RBL1,HIPK2,STAT6,DNAJC17,STAT1,BEND3,SMAD4,LRP8,CBX4,NCOR2,MECP2,TCF3,PAWR,MXD4,HMG20A,FOXO3,MAD2L2,WWP2,SUV39H2,H2AFY,CITED2,STAT3,NCOA2,TGFB1,ZNF202,RCOR1,MEN1,GPS2,ZHX1,E2F1,DDX5,RBPJ,NR2F2,IGBP1,IFI16 |
| 1.479e-02 | -4.21 | C-MYC pathway | Pathway Interaction DB | myc_pathway | 22 | 9 | 2226 | 426 |
PPP2CA,MAX,KAT2A,PPP2R5A,PIN1,AXIN1,TAF12,RUVBL2,SUPT7L |
| 1.479e-02 | -4.21 | GSE42021_TREG_PLN_VS_CD24INT_TREG_THYMUS_UP | MSigDB lists | GSE42021_TREG_PLN_VS_CD24INT_TREG_THYMUS_UP | 194 | 41 | 17377 | 2626 |
OTUD5,ZNF207,IER2,MAPRE1,PPP1R15B,SRGN,YTHDF3,AGFG1,NOTCH2,CSNK1A1,KCMF1,RNF103,PNO1,CRKL,SLC31A1,MDM2,VASP,PSMA6,NEK6,TANK,TRA2B,TARDBP,ASB6,IFRD1,CYFIP1,BIRC3,MAP4K4,ILF3,GTPBP4,PFKFB3,PBRM1,RHOB,HSPA1B,RAB18,TAB2,GADD45B,ADAM9,DDX5,TMEM159,MAP3K5,B4GALT3 |
| 1.479e-02 | -4.21 | GSE17301_CTRL_VS_48H_ACD3_ACD28_IFNA5_STIM_CD8_TCELL_DN | MSigDB lists | GSE17301_CTRL_VS_48H_ACD3_ACD28_IFNA5_STIM_CD8_TCELL_DN | 194 | 41 | 17377 | 2626 |
CYTIP,PLXNC1,HJURP,PMS2,CDCA3,KIF23,GYG1,AP1B1,STMN1,FBXO5,MBD4,PCNA,CCNA2,SOCS6,FNIP2,PRADC1,POLK,PBK,LRBA,PIP4K2C,LNX2,WDHD1,CKAP2L,STX16,PDE3B,SH3GLB1,MAPK3,TBC1D17,MID1IP1,JAK1,RBL1,HIPK2,NFIL3,CEBPG,ST3GAL2,HEXA,PDSS2,ESPL1,TUBB,DDB1,PTOV1 |
| 1.482e-02 | -4.21 | GO_NEGATIVE_REGULATION_OF_INTRACELLULAR_PROTEIN_TRANSPORT | MSigDB lists | GO_NEGATIVE_REGULATION_OF_INTRACELLULAR_PROTEIN_TRANSPORT | 96 | 23 | 17377 | 2626 |
CYLD,TXN,NF1,GOPC,RAB23,RANGAP1,SOX4,PARK7,AKAP1,CDK5,KEAP1,SP100,CSK,TONSL,SRI,OGT,AXIN2,FAM89B,PKD2,MDFIC,PARP10,FAF1,SVIP |
| 1.483e-02 | -4.21 | SUGP1 (SURP and G-patch domain containing 1) | protein interactions | 57794 | 61 | 17 | 17029 | 2761 |
PPIF,PPIB,SCAMP3,VDAC2,NDUFA7,VDAC1,UBE2I,SPR,SF3A2,DHX15,LMNA,RBM17,NDUFA2,PQBP1,NABP2,CTR9,RBMS1 |
| 1.483e-02 | -4.21 | TENT5A (terminal nucleotidyltransferase 5A) | protein interactions | 55603 | 61 | 17 | 17029 | 2761 |
BCCIP,KEAP1,DCAF6,TRAFD1,TRIP12,JAK1,POLR2J,DGCR8,TMEM39A,ZNHIT6,SLC16A1,ATXN1,NR2F2,WDR62,RNF14,ESPL1,CBX4 |
| 1.483e-02 | -4.21 | LIG3 (DNA ligase 3) | protein interactions | 3980 | 61 | 17 | 17029 | 2761 |
RPA2,JMJD4,TDP1,MAX,H2AFX,JTB,TOP3A,KIF23,RACGAP1,NFATC2,WDR76,PREPL,NCAPG,RSAD1,APP,RPA1,XRCC5 |
| 1.483e-02 | -4.21 | SELENBP1 (selenium binding protein 1) | protein interactions | 8991 | 61 | 17 | 17029 | 2761 |
MMACHC,FAM49B,SUCLG1,RAB11B,FLYWCH2,SUMO2,MEMO1,WDHD1,GORASP2,COA7,RPA1,TBC1D14,DUT,CAMKMT,TFG,SINHCAF,SMARCD1 |
| 1.483e-02 | -4.21 | DYRK2 (dual specificity tyrosine phosphorylation regulated kinase 2) | protein interactions | 8445 | 61 | 17 | 17029 | 2761 |
KIF3B,RPS2,RB1CC1,XPNPEP3,APP,HSPA1B,RAD54B,RPA1,MOAP1,MDM2,DAP3,CCP110,SP100,SIAH2,WDR62,DCAF5,DDB1 |
| 1.483e-02 | -4.21 | GPRASP2 (G protein-coupled receptor associated sorting protein 2) | protein interactions | 114928 | 61 | 17 | 17029 | 2761 |
FYTTD1,RPS2,TXN,ASPM,RAF1,AGO2,WDR18,COPE,CUL3,MYO9B,CDC73,NDUFS7,CHCHD3,KEAP1,AP1M1,TRIM32,CCDC59 |
| 1.486e-02 | -4.21 | MONNIER_POSTRADIATION_TUMOR_ESCAPE_DN | MSigDB lists | MONNIER_POSTRADIATION_TUMOR_ESCAPE_DN | 343 | 67 | 17377 | 2626 |
IER2,GLT8D1,ZBTB10,CKLF,UGP2,CAST,TSC22D3,HEXB,RCOR3,ABHD14A,PRNP,EEF2K,DECR1,RABGAP1L,RNF19A,APOOL,PDIA6,CTDSP2,ADCY7,KLF10,PBXIP1,KIAA0040,OAF,HTATIP2,TOR1AIP2,AMDHD2,PRKRA,STK17B,PLEKHF2,HSPB11,WDR11,RBL1,STAT1,CLU,FBXL3,CHID1,MZT1,HJURP,GADD45G,FLOT1,RPL15,CDK13,PPP3CB,ITGB5,EBP,TMCC3,SSBP3,ANP32A,BCL2,CNOT6L,NCOA2,ANKRD37,ACSL3,RFXANK,PNPLA8,SRSF5,KLF6,RHOB,CAT,TTC13,ORMDL2,SIL1,ACAT1,HMGB2,RBPJ,TMEM159,SNX14 |
| 1.491e-02 | -4.21 | negative regulation of protein tyrosine kinase activity | biological process | GO:0061099 | 27 | 9 | 17256 | 2622 |
PTPN2,SH3BP5,FGFR1OP,GGNBP2,SOCS4,MVP,PSEN1,VPS25,SOCS5 |
| 1.491e-02 | -4.21 | regulation of transcription elongation from RNA polymerase II promoter | biological process | GO:0034243 | 27 | 9 | 17256 | 2622 |
PAF1,BRD4,ZMYND11,AXIN1,CTR9,RTF1,CDC73,SUPT16H,GTF2F1 |
| 1.493e-02 | -4.20 | superpathway of purine nucleotides de novo biosynthesis I | BIOCYC pathways | META_PWY-841 | 13 | 6 | 902 | 157 |
IMPDH1,RRM2,GART,GUK1,ATIC,RRM1 |
| 1.494e-02 | -4.20 | positive regulation of telomere maintenance via telomere lengthening | biological process | GO:1904358 | 36 | 11 | 17256 | 2622 |
HNRNPA2B1,MAP3K4,CCT2,NEK7,AURKB,MAPK1,PARN,POT1,CCT8,XRCC5,MAPK3 |
| 1.494e-02 | -4.20 | nucleotide-sugar metabolic process | biological process | GO:0009225 | 36 | 11 | 17256 | 2622 |
UAP1,GNPNAT1,GUK1,UGP2,TSTA3,GNPDA1,PARG,GNE,FUT8,NANS,AMDHD2 |
| 1.496e-02 | -4.20 | Plk4 (polo like kinase 4) | protein interactions | 20873 | 4 | 3 | 17029 | 2761 |
PTMS,SMAD4,NACA |
| 1.496e-02 | -4.20 | ZNF140 (zinc finger protein 140) | protein interactions | 7699 | 4 | 3 | 17029 | 2761 |
TRIM28,CAND1,SRPK2 |
| 1.496e-02 | -4.20 | APOO (apolipoprotein O) | protein interactions | 79135 | 4 | 3 | 17029 | 2761 |
APOOL,CDK2,TIMMDC1 |
| 1.496e-02 | -4.20 | BSDC1 (BSD domain containing 1) | protein interactions | 55108 | 4 | 3 | 17029 | 2761 |
PHC2,KLC1,TMEM216 |
| 1.496e-02 | -4.20 | PIGC (phosphatidylinositol glycan anchor biosynthesis class C) | protein interactions | 5279 | 4 | 3 | 17029 | 2761 |
KLF10,ZHX1,PIGQ |
| 1.496e-02 | -4.20 | CLDN10 (claudin 10) | protein interactions | 9071 | 4 | 3 | 17029 | 2761 |
ATE1,VKORC1,LMNA |
| 1.496e-02 | -4.20 | NAP1L2 (nucleosome assembly protein 1 like 2) | protein interactions | 4674 | 4 | 3 | 17029 | 2761 |
CUL1,FBL,PPP3R1 |
| 1.496e-02 | -4.20 | Trim35 (tripartite motif-containing 35) | protein interactions | 66854 | 4 | 3 | 17029 | 2761 |
SMAD2,SMURF1,SMAD4 |
| 1.496e-02 | -4.20 | ALG10B (ALG10B, alpha-1,2-glucosyltransferase) | protein interactions | 144245 | 4 | 3 | 17029 | 2761 |
TRAFD1,ATP5F1B,NPLOC4 |
| 1.496e-02 | -4.20 | Traf6 (TNF receptor-associated factor 6) | protein interactions | 22034 | 4 | 3 | 17029 | 2761 |
UBE2D3,UBE2V1,MAP3K14 |
| 1.496e-02 | -4.20 | RGPD6 (RANBP2-like and GRIP domain containing 6) | protein interactions | 729540 | 4 | 3 | 17029 | 2761 |
RANGAP1,MCM2,CD81 |
| 1.496e-02 | -4.20 | HES5 (hes family bHLH transcription factor 5) | protein interactions | 388585 | 4 | 3 | 17029 | 2761 |
BLM,PTEN,STAT3 |
| 1.496e-02 | -4.20 | GAS2 (growth arrest specific 2) | protein interactions | 2620 | 4 | 3 | 17029 | 2761 |
CAPN2,APP,CAPN1 |
| 1.496e-02 | -4.20 | SLC18A2 (solute carrier family 18 member A2) | protein interactions | 6571 | 4 | 3 | 17029 | 2761 |
CSNK2A1,CSNK1A1,PARK7 |
| 1.496e-02 | -4.20 | ZGRF1 (zinc finger GRF-type containing 1) | protein interactions | 55345 | 4 | 3 | 17029 | 2761 |
KIF11,APP,CDKN2A |
| 1.496e-02 | -4.20 | ZNF845 (zinc finger protein 845) | protein interactions | 91664 | 4 | 3 | 17029 | 2761 |
MPHOSPH8,TRIM28,GPATCH4 |
| 1.496e-02 | -4.20 | CHIT1 (chitinase 1) | protein interactions | 1118 | 4 | 3 | 17029 | 2761 |
ALDH3B1,VHL,RPL11 |
| 1.496e-02 | -4.20 | DKK4 (dickkopf WNT signaling pathway inhibitor 4) | protein interactions | 27121 | 4 | 3 | 17029 | 2761 |
CUL1,LRP5,IDE |
| 1.496e-02 | -4.20 | ALKBH7 (alkB homolog 7) | protein interactions | 84266 | 4 | 3 | 17029 | 2761 |
KRAS,APP,NDUFS7 |
| 1.496e-02 | -4.20 | Lmnb1 (lamin B1) | protein interactions | 116685 | 4 | 3 | 17029 | 2761 |
CCNA2,CCNB1,CDK2 |
| 1.496e-02 | -4.20 | ZFP57 (ZFP57 zinc finger protein) | protein interactions | 346171 | 4 | 3 | 17029 | 2761 |
DNMT3A,DNMT1,TRIM28 |
| 1.496e-02 | -4.20 | RPSAP58 (ribosomal protein SA pseudogene 58) | protein interactions | 388524 | 4 | 3 | 17029 | 2761 |
EWSR1,MCM2,RPSA |
| 1.496e-02 | -4.20 | VSTM2L (V-set and transmembrane domain containing 2 like) | protein interactions | 128434 | 4 | 3 | 17029 | 2761 |
ATXN1,CCM2,SRPK2 |
| 1.496e-02 | -4.20 | Dusp9 (dual specificity phosphatase 9) | protein interactions | 75590 | 4 | 3 | 17029 | 2761 |
MAPK1,MAPK14,MAPK3 |
| 1.496e-02 | -4.20 | IDO1 (indoleamine 2,3-dioxygenase 1) | protein interactions | 3620 | 4 | 3 | 17029 | 2761 |
TERF2IP,DDX24,APP |
| 1.496e-02 | -4.20 | ORF11 (ORF11) | protein interactions | 4961439 | 4 | 3 | 17029 | 2761 |
SHOC2,KPNA4,MRS2 |
| 1.496e-02 | -4.20 | LOC442497 (uncharacterized LOC442497) | protein interactions | 442497 | 4 | 3 | 17029 | 2761 |
RPA2,EYA2,RPA1 |
| 1.496e-02 | -4.20 | LYSMD1 (LysM domain containing 1) | protein interactions | 388695 | 4 | 3 | 17029 | 2761 |
TCF12,GOLGA2,TULP3 |
| 1.496e-02 | -4.20 | HYLS1 (HYLS1, centriolar and ciliogenesis associated) | protein interactions | 219844 | 4 | 3 | 17029 | 2761 |
IDE,GOLGA2,HAUS8 |
| 1.496e-02 | -4.20 | mug82 (putative translation release factor) | protein interactions | 2541472 | 4 | 3 | 17029 | 2761 |
DAP3,MRPL3,MRPL12 |
| 1.496e-02 | -4.20 | ZNF35 (zinc finger protein 35) | protein interactions | 7584 | 4 | 3 | 17029 | 2761 |
CREB1,APP,CDC5L |
| 1.497e-02 | -4.20 | secretory granule lumen | cellular component | GO:0034774 | 320 | 62 | 18223 | 2701 |
ADA2,MIF,GMFG,HEXB,SRGN,OLA1,NIT2,MAN2B1,NHLRC3,GYG1,MAPK14,APP,FERMT3,PCYOX1L,GNS,PA2G4,PSMD2,PSMD1,ARPC5,HUWE1,OSTF1,CNN2,APOOL,MVP,GM2A,SPTAN1,TGFB1,CYFIP1,FTL,CCT2,TIMP2,FAM49B,CREG1,ARHGAP45,PPIE,PSMB7,C1orf35,HEBP2,PKM,TOLLIP,ARMC8,CCT8,NEU1,CAND1,XRCC5,MAGED2,CAT,DSN1,PSMD3,FAM3C,ACLY,IMPDH1,CAB39,CANT1,CTSA,CLU,GPI,PDXK,ROCK1,PGAM1,MAPK1,TUBB |
| 1.501e-02 | -4.20 | GSE43863_NAIVE_VS_MEMORY_LY6C_INT_CXCR5POS_CD4_TCELL_D150_LCMV_UP | MSigDB lists | GSE43863_NAIVE_VS_MEMORY_LY6C_INT_CXCR5POS_CD4_TCELL_D150_LCMV_UP | 183 | 39 | 17377 | 2626 |
WASF2,CYTIP,HECA,TSC22D3,ACAP1,SMC6,MYH9,CREBL2,HAUS4,CDC42SE2,GIT2,MAN1A1,APLP2,RB1,ADD3,KDM2A,RCSD1,ZNF260,SLC44A1,RP2,MAP3K14,FRMD8,SNX8,KDM3B,CYFIP1,PPP3CA,TACC1,RB1CC1,PARP4,PLEC,PRKRA,SERP1,TFEB,HHEX,CSK,RNF38,ARRDC1,ABCA1,PDCD4 |
| 1.501e-02 | -4.20 | GSE13493_CD4INTCD8POS_VS_CD8POS_THYMOCYTE_UP | MSigDB lists | GSE13493_CD4INTCD8POS_VS_CD8POS_THYMOCYTE_UP | 183 | 39 | 17377 | 2626 |
ZNF207,NDUFV2,CMAS,CDC40,ADAM10,TATDN3,LAGE3,MED13L,MEF2A,SNN,AP3S1,LYRM2,HMG20A,PRNP,FGFR3,MLX,PTEN,RABGAP1L,RCSD1,TTC9C,BTF3L4,CHTOP,MAML1,LDHB,CDKN2AIP,TOR1AIP2,BCLAF1,DNAJA1,MEN1,C9orf40,MCFD2,PLEKHF2,SCARB2,RBMX,PKD2,MAP3K5,DCAF5,NXT2,DDX42 |
| 1.501e-02 | -4.20 | GSE11057_CD4_EFF_MEM_VS_PBMC_UP | MSigDB lists | GSE11057_CD4_EFF_MEM_VS_PBMC_UP | 183 | 39 | 17377 | 2626 |
HECA,LIME1,CASP6,ANKH,ANK3,SLC39A13,LANCL1,DNAJB1,CD59,GSTK1,ZNF75D,ATIC,BDH1,KIF22,MAP3K14,FAM171A1,CAMK2G,NIPAL3,CCDC57,PBXIP1,ITM2A,ADSL,ESYT1,ICAM2,EML4,NMT2,RPSA,PRIM1,STOML2,EPB41,OPTN,ZNF862,SEPT1,ATP1A1,HINT1,CAB39,PRMT7,CHMP7,SVIP |
| 1.501e-02 | -4.20 | GSE2197_CPG_DNA_VS_UNTREATED_IN_DC_UP | MSigDB lists | GSE2197_CPG_DNA_VS_UNTREATED_IN_DC_UP | 183 | 39 | 17377 | 2626 |
TMEM184B,AGTRAP,PPP1R15B,RHOC,ARID5A,AP3M2,SNN,SLC20A1,GGPS1,SRXN1,RAB21,MDM2,VASP,PSMD1,UTP18,TSHZ1,ENPP4,ACP2,ELL2,HARS,USP42,WBP2,MIER2,CAPZA2,AZI2,OGFR,RAB22A,RHBDF2,KPNA4,TAB2,PFDN4,PRDX5,STAT1,CHMP4B,BEND3,RRS1,SMNDC1,ZC3HAV1,RNF114 |
| 1.501e-02 | -4.20 | GSE23984_CTRL_VS_HYPOCALEMIC_VITAMIND_ANALOG_TCELL_DN | MSigDB lists | GSE23984_CTRL_VS_HYPOCALEMIC_VITAMIND_ANALOG_TCELL_DN | 183 | 39 | 17377 | 2626 |
HIVEP3,NSMCE4A,PLXNC1,REPS2,EYA1,FAM129A,C5orf30,KTN1,PIP4K2A,EEF2K,APLP2,TNS3,SIAH1,MBD2,BRI3,SLC35C2,SGCB,DRAM2,SNX8,MAPRE2,LONRF3,ETV3,GALC,DENND4C,ZMYND11,OXR1,SLC16A7,WIPF1,FRAT2,DNAJC9,MAP4K3,RAB22A,ARF4,PLEKHF2,SH3BP5,TSC1,DUSP3,ATF6,PDCD4 |
| 1.501e-02 | -4.20 | GSE27786_LSK_VS_BCELL_DN | MSigDB lists | GSE27786_LSK_VS_BCELL_DN | 183 | 39 | 17377 | 2626 |
NSMCE4A,ANKRD13D,RAC1,MON1B,CTCF,CSNK2A1,SNN,RLF,TMEM161B,NDUFS4,WRNIP1,CRKL,RAP1A,PTEN,ATG3,DAD1,MBD2,ARHGEF1,AKAP8,CREB1,MVP,GNAI2,USP34,CIC,VHL,EMP3,ARHGDIB,ESYT1,KDM1B,NECAP2,EIF4ENIF1,OSBPL11,SERF2,CLK3,NIP7,GRIPAP1,PARG,TCOF1,HIGD2A |
| 1.501e-02 | -4.20 | GSE18791_UNSTIM_VS_NEWCATSLE_VIRUS_DC_18H_UP | MSigDB lists | GSE18791_UNSTIM_VS_NEWCATSLE_VIRUS_DC_18H_UP | 183 | 39 | 17377 | 2626 |
NDUFA5,SCYL1,ZFYVE21,EBNA1BP2,IL21R,LCLAT1,ELMOD2,ERH,DDX56,EXOSC7,INTS7,NVL,INTS1,PPCDC,ACAD8,CNPY3,STRAP,MED22,CAMK2G,SEH1L,PHF10,CSRP1,TSTA3,PRKDC,WDR1,PCGF6,BMS1,NUP155,UBE4B,TOLLIP,TRAM2,NIP7,TIMM17A,CDCA7L,SLC25A19,CAB39,PITPNA,B4GALT3,HDAC2 |
| 1.501e-02 | -4.20 | GSE32986_GMCSF_VS_GMCSF_AND_CURDLAN_HIGHDOSE_STIM_DC_UP | MSigDB lists | GSE32986_GMCSF_VS_GMCSF_AND_CURDLAN_HIGHDOSE_STIM_DC_UP | 183 | 39 | 17377 | 2626 |
CDS2,REPS2,TSC22D3,TMEM41B,GADD45G,TATDN3,CERK,RRAGC,GYG1,MXD4,ATP6V1B2,RGS2,APH1B,RCOR3,PPP1R3B,PPP1R12C,SOCS6,TPST1,FAM89B,MDFIC,ATP6V0D1,TRIM14,TIMP2,POLR2G,LONRF3,NQO2,KIAA0930,RHOB,PI4K2A,OSBPL11,HIPK2,WDR7,PGRMC1,APPL2,CTSA,PDXK,PREPL,EHD4,RAB3IL1 |
| 1.501e-02 | -4.20 | GSE360_CTRL_VS_L_MAJOR_MAC_DN | MSigDB lists | GSE360_CTRL_VS_L_MAJOR_MAC_DN | 183 | 39 | 17377 | 2626 |
UBE2D3,MAPRE1,NQO1,PPP1R2,GADD45G,ACAP1,KCTD17,PLAGL2,PPP3CB,BIRC2,RGS1,SPAG5,HOMER1,CLIC4,PHF14,SRSF4,DNM2,CDKN1B,NUP153,MDFIC,TECR,PTPRK,CPNE1,ELL2,TOP3A,HTATIP2,MTMR6,DCTD,ZNF174,TWISTNB,OPTN,CLK3,PSMD8,SNAP23,PGRMC1,SMAD1,TRAF5,NUDT3,SMNDC1 |
| 1.501e-02 | -4.20 | KAECH_NAIVE_VS_MEMORY_CD8_TCELL_UP | MSigDB lists | KAECH_NAIVE_VS_MEMORY_CD8_TCELL_UP | 183 | 39 | 17377 | 2626 |
RPS2,ST13,DAP,TIA1,KIF23,MXD4,PIP4K2A,BIRC2,PAPOLA,IL6ST,MECR,ANP32A,TTC3,METTL9,RPL22L1,SMC4,ADCY7,USP34,POU2AF1,NRAS,MIOS,BIRC3,RBX1,RAB3IP,ZFAND5,BTBD1,CYB5A,ZFR,ANKRD10,NAP1L1,ETS2,RWDD4,PSAP,ACADM,CDK2,RNF14,HDAC2,PTOV1,S100PBP |
| 1.501e-02 | -4.20 | GSE40274_HELIOS_VS_FOXP3_AND_HELIOS_TRANSDUCED_ACTIVATED_CD4_TCELL_DN | MSigDB lists | GSE40274_HELIOS_VS_FOXP3_AND_HELIOS_TRANSDUCED_ACTIVATED_CD4_TCELL_DN | 183 | 39 | 17377 | 2626 |
HIVEP3,SCOC,HAUS4,MRPL19,KIAA1147,SSR1,SPPL2A,TMCC3,RAP1A,SHC1,CENPJ,RAB35,ATP6V0A2,CLTB,F2R,ZNF770,PACS2,RBM15B,VOPP1,CSNK1G2,SEPT9,PGGT1B,TSPYL4,HSDL1,PDE3B,USP36,HSPA1B,ZNF330,CORO1C,KBTBD7,ACAT1,MBOAT1,SSNA1,PDXK,SPRYD4,SMAD1,PDLIM5,PITRM1,GPATCH4 |
| 1.503e-02 | -4.20 | DAP3 (death associated protein 3) | protein interactions | 7818 | 85 | 22 | 17029 | 2761 |
MRPS2,MRPS15,POC1A,RPL6,MRPS10,HAUS2,FADD,STOML2,DAP3,GRSF1,ZNF746,MRPS27,COX5A,TRMT10B,DUSP11,TARDBP,RBM3,RRS1,SNRNP70,ZC3H3,CCDC59,CSNK1D |
| 1.503e-02 | -4.20 | ASNS (asparagine synthetase (glutamine-hydrolyzing)) | protein interactions | 440 | 85 | 22 | 17029 | 2761 |
UBQLN4,LARS,STRN4,OLA1,RRM2,ATXN1,TWF2,SDHA,MAT2A,NPLOC4,MAPK3,CAPN2,EPRS,AHNAK,HSPBP1,IARS,QARS,AHSA1,DDA1,CDK2,NMD3,CSTF1 |
| 1.503e-02 | -4.20 | benign | COSMIC cancer mutations | benign | 272 | 54 | 17385 | 2587 |
MAX,PNISR,NPHP4,ZCCHC8,NF1,MRPL39,ANK3,SMARCA4,ZNF107,EIF2AK4,NOTCH2,ZADH2,SDHA,FAM8A1,CHD1,GNB2,NUP205,RAB35,RAD23B,DCP1A,CTR9,NAP1L4,APOOL,ZRANB1,STAT3,RNLS,ZNF189,PTPRK,CNTN5,NRAS,SEPT9,GUK1,PPT1,GALC,VHL,KRAS,CAPZA2,KMT2C,MPG,PRPSAP1,ZNF407,STYXL1,AHNAK,FNTA,PALB2,CTSA,WIPI2,AKNA,ZNF598,ABCA1,TERF1,HRAS,CDKN2A,PFKP |
| 1.505e-02 | -4.20 | GO_ENZYME_LINKED_RECEPTOR_PROTEIN_SIGNALING_PATHWAY | MSigDB lists | GO_ENZYME_LINKED_RECEPTOR_PROTEIN_SIGNALING_PATHWAY | 677 | 123 | 17377 | 2626 |
WASF2,RAB14,REPS2,TSC2,ADAM10,RAF1,ACTR3,RAC1,SIRT2,ATP6V1B2,DUSP22,MAPK14,LYN,CPNE3,ABL2,VAV1,ATP6V0B,PDK2,SHC1,CDC42,CD3EAP,MTMR4,IL6ST,PIK3R2,AP2B1,ZFYVE27,TIPARP,ABI1,CDC37,PTPRK,ATP6V1G1,SHOC2,NRAS,KLF10,POLR2G,POLR2L,NCK1,APH1A,AKT2,HNRNPF,POLR2D,ATP6V0A1,SHCBP1,ZFAND5,GIGYF1,ARF4,SOCS7,SMAD2,IDE,JAK1,RPS27A,HIPK2,ITGB1,ADAM9,ATP6V0C,ACTB,ROCK1,SMAD1,ARRB2,MAPK1,SMURF1,AP2S1,SMAD4,ATP6V0E1,PARD3,UBE2D3,POLR2K,VAV2,TRIO,SDC2,TIA1,AKT1S1,NCKAP1,AP3S1,APH1B,ITGB5,GTF2F1,PTPN2,FKBP1A,FGFR3,SUB1,PTEN,ARPC5,MEGF8,FUT8,PTPN11,ATP6V0A2,CREB1,MVP,CITED2,STAT3,ATP6V0D1,UBE2M,HNRNPM,SOCS5,PDPK1,TGFB1,CYFIP1,ADAM17,POLR2I,RHOA,MAPKAPK3,KRAS,ADRB2,CYFIP2,ARPC1A,APPL1,POLR2A,MAPK3,PTPRF,FNTA,ATP6V1D,PDCD6,LTBP4,POLR2J,CSK,ELMO1,TWSG1,PML,ATP6V1C1,TOB1,HRAS,FAM83G |
| 1.506e-02 | -4.20 | GO_ATPASE_ACTIVITY_COUPLED_TO_MOVEMENT_OF_SUBSTANCES | MSigDB lists | GO_ATPASE_ACTIVITY_COUPLED_TO_MOVEMENT_OF_SUBSTANCES | 112 | 26 | 17377 | 2626 |
ATP13A1,ABCA3,ABCC10,ATP2C1,TAP1,ATP6V0A1,ABCB10,ATP6V1B2,ATP6V0B,ATP1A1,ATP6V1D,ATP2A2,ATP13A3,ATP6V0A2,ANXA5,ASNA1,ABCD1,TAP2,ATP6V0C,ATP6V1C1,ATP6V0E1,ATP6V0D1,ABCA1,ABCC1,ABCC5,ATP6V1G1 |
| 1.508e-02 | -4.19 | haematopoietic_and_lymphoid_tissue-lymph_node-lymphoid_neoplasm-follicular_lymphoma | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-lymph_node-lymphoid_neoplasm-follicular_lymphoma | 220 | 45 | 17385 | 2587 |
PHF23,FAM129A,B4GALT1,PM20D2,ZNF267,NOTCH2,ARID1B,ANKIB1,DDRGK1,KRI1,CSDE1,RB1,UBE2Q2,EIF4A3,HUWE1,PTEN,BCL2,GNAI2,TSHZ1,POU2AF1,NRAS,TNFAIP3,ELL2,BTG2,MKI67,KRAS,ARID1A,PLEC,CHCHD6,FAS,ZMYM3,TBC1D17,RBM25,GPS2,STAT6,LY75,ARRDC1,XRCC3,E2F2,UNC13C,ABCA1,TSPAN5,HRAS,CDKN2A,ADAM23 |
| 1.512e-02 | -4.19 | protein targeting to mitochondrion | biological process | GO:0006626 | 60 | 16 | 17256 | 2622 |
TIMM8B,TOMM20,MTX3,TIMM21,MTX1,TOMM40,MFN2,TIMM13,HSPA4,TIMM23,TIMM17A,TIMM29,FBXO7,PITRM1,MTX2,TIMM50 |
| 1.512e-02 | -4.19 | regulation of peptidyl-lysine acetylation | biological process | GO:2000756 | 60 | 16 | 17256 | 2622 |
TGFB1,KAT2A,EID1,KAT7,MECP2,PRKAA1,NOC2L,WBP2,BRD7,RUVBL2,BRCA1,SOX4,SMAD4,HDAC2,MAPK3,IWS1 |
| 1.512e-02 | -4.19 | histone deacetylation | biological process | GO:0016575 | 60 | 16 | 17256 | 2622 |
BAZ2A,MTA2,MIER1,RCOR1,MIER2,SIRT2,MBD3,BRMS1,CHD3,HDAC7,MTA1,RBBP4,SAP30L,HDAC2,ARID4A,SAP30 |
| 1.512e-02 | -4.19 | iron ion transport | biological process | GO:0006826 | 60 | 16 | 17256 | 2622 |
FTL,RAB11B,ATP6V0A1,ATP6V1B2,PICALM,SLC25A37,TFRC,ATP6V0B,ATP6V1D,DNM2,ATP6V0A2,ATP6V0C,ATP6V1C1,ATP6V0E1,ATP6V0D1,ATP6V1G1 |
| 1.514e-02 | -4.19 | TAB1 (TGF-beta activated kinase 1 (MAP3K7) binding protein 1) | protein interactions | 10454 | 135 | 32 | 17029 | 2761 |
C9orf78,PDCD6IP,CYLD,CASP6,MAGED1,XIAP,CNTROB,XPO7,MAPK14,PARK7,PHC2,MDM2,CORO1A,F2R,CFL1,BIRC3,RBX1,LAP3,ZMYND11,PRMT2,MCM2,FADD,CYB5A,EPRS,HSPBP1,TAB2,HNRNPR,OGT,ARAP1,RPLP1,SMURF1,ARRB2 |
| 1.514e-02 | -4.19 | DISC1 (DISC1 scaffold protein) | protein interactions | 27185 | 135 | 32 | 17029 | 2761 |
IMMT,DCTN2,TRIO,MEMO1,SMC2,MACF1,MATR3,EIF3H,DPYSL3,DST,SH3BP5,FBXO41,CDC16,SMC3,GOLGA2,DPYSL2,STX18,PPP4R1,EXOC4,KIFAP3,YWHAZ,CEP63,CLU,PPP5C,MVP,NDE1,SMARCE1,ANKHD1,TUBB,DCTN1,SPTAN1,CDC5L |
| 1.514e-02 | -4.19 | GSE32255_WT_VS_JMJD2D_KNOCKDOWN_4H_LPS_STIM_DC_UP | MSigDB lists | GSE32255_WT_VS_JMJD2D_KNOCKDOWN_4H_LPS_STIM_DC_UP | 139 | 31 | 17377 | 2626 |
UBE2E2,GPR132,NRAS,ETV3,MAP4K4,ITM2A,RFFL,MYO9B,GALNT7,RAB3IP,UBQLN2,TANC1,ICAM2,SLC20A1,APP,FBXO21,PDLIM1,ETS2,SYNM,IARS,ZNRF2,TATDN2,BDH1,DAPK1,AHDC1,NDUFS5,RNF19A,PLCL2,NUDT11,PDLIM5,EYA2 |
| 1.517e-02 | -4.19 | CTACTGT,MIR-199A | MSigDB lists | CTACTGT,MIR-199A | 172 | 37 | 17377 | 2626 |
NAT14,DNMT3A,PPP1R12A,CCM2,SNN,TMEM161B,APLP2,SUB1,ITGB8,CDC42,PDS5B,CITED2,RLIM,YTHDC1,MEF2D,LRRC1,TANC1,FXR1,KDM3A,EML4,RAB2B,PHF6,MAP3K4,GOLGA4,RBM25,TAB2,ZHX1,LUC7L3,STAT6,CSNK1G1,GOLGA8A,PROSER1,MBD6,USP11,TSPAN5,ABCA1,RNF139 |
| 1.517e-02 | -4.19 | GSE20727_CTRL_VS_ROS_INH_AND_DNFB_ALLERGEN_TREATED_DC_UP | MSigDB lists | GSE20727_CTRL_VS_ROS_INH_AND_DNFB_ALLERGEN_TREATED_DC_UP | 172 | 37 | 17377 | 2626 |
COX5B,NQO1,MRI1,NACA,KLF13,HMGN3,COX4I1,MAN2B1,RSAD1,CSDE1,BANF1,RCSD1,ANP32A,TAGLN2,MRPL40,TECR,METTL9,RNF26,ZNRD1,PABPC1,TMEM14C,PCBP2,KCNAB2,GPX4,PHF10,ZFP64,OAF,ECH1,ZMYM3,AKAP1,GNA12,EPRS,RAD51C,U2SURP,PSAP,DNAJC30,TFDP2 |
| 1.517e-02 | -4.19 | GSE17974_CTRL_VS_ACT_IL4_AND_ANTI_IL12_2H_CD4_TCELL_UP | MSigDB lists | GSE17974_CTRL_VS_ACT_IL4_AND_ANTI_IL12_2H_CD4_TCELL_UP | 172 | 37 | 17377 | 2626 |
WASF2,WDYHV1,ACAP1,NIT2,SNN,RGS2,EPHX2,RGS1,ANKRD39,NUDT19,NUP210,THADA,AP3S2,RCSD1,CNPY4,TAGLN2,MRPL40,CITED2,GPD1L,ABCC5,PGAP2,HEMK1,POLR3GL,SUMF2,MEF2D,LY6E,TAZ,ANKRD10,WAS,VPS26B,KLHL15,DTD1,PIEZO1,ZMIZ1,RPS6KC1,TOB1,RHEBL1 |
| 1.517e-02 | -4.19 | GSE6092_B_BURGDOFERI_VS_B_BURGDORFERI_AND_IFNG_STIM_ENDOTHELIAL_CELL_DN | MSigDB lists | GSE6092_B_BURGDOFERI_VS_B_BURGDORFERI_AND_IFNG_STIM_ENDOTHELIAL_CELL_DN | 172 | 37 | 17377 | 2626 |
DNAJC2,RRP15,AGRN,TRIP10,EIF3D,PLAGL2,UBE2Z,USP39,BIRC2,PNO1,KIF5B,MEX3C,ITGB8,CS,CLDND1,RNF19A,MVP,ABI1,ACSL5,TSHZ1,SHOC2,TNFAIP3,NCK1,WDR1,USP42,AMD1,MKI67,SEPT7,DDX39A,APPL1,PSMC4,PPP2CA,SYNCRIP,GADD45B,RGL1,SMURF1,MRPL3 |
| 1.524e-02 | -4.18 | FHL1 (four and a half LIM domains 1) | protein interactions | 2273 | 34 | 11 | 17029 | 2761 |
HIVEP3,DEAF1,EWSR1,SMAD2,RBPJ,SMURF1,SMAD4,CBX4,LMNA,CSNK1D,PRNP |
| 1.524e-02 | -4.18 | RALB (RAS like proto-oncogene B) | protein interactions | 5899 | 34 | 11 | 17029 | 2761 |
EXOC3,REPS2,TULP3,TPP2,EXOC4,EI24,LAMTOR3,HAUS4,ALDH18A1,MAPK14,REPS1 |
| 1.524e-02 | -4.18 | RHOBTB3 (Rho related BTB domain containing 3) | protein interactions | 22836 | 34 | 11 | 17029 | 2761 |
HGS,RHOBTB3,NUP210,RBX1,VHL,ARF5,PBK,CUL3,CCNB1,EGLN1,FAS |
| 1.524e-02 | -4.18 | NEK4 (NIMA related kinase 4) | protein interactions | 6787 | 34 | 11 | 17029 | 2761 |
ANKRD28,HLA-B,PRKAB1,NPHP4,CBWD2,HLA-E,DNAJB2,CBWD1,BLM,CTDSP2,GLMP |
| 1.524e-02 | -4.18 | CNOT8 (CCR4-NOT transcription complex subunit 8) | protein interactions | 9337 | 34 | 11 | 17029 | 2761 |
UNK,GPBP1L1,BTG2,GADD45B,AGO2,CNOT6,CAPZA2,USP11,CNOT11,TOB1,CNOT3 |
| 1.524e-02 | -4.18 | TAF1A (TATA-box binding protein associated factor, RNA polymerase I subunit A) | protein interactions | 9015 | 34 | 11 | 17029 | 2761 |
UBTF,RRN3,NIFK,CD3EAP,ZNF512,RBM34,MECP2,ANP32A,JMJD6,TAF12,NKAPD1 |
| 1.524e-02 | -4.18 | VPS37C (VPS37C, ESCRT-I subunit) | protein interactions | 55048 | 34 | 11 | 17029 | 2761 |
HGS,PDCD6IP,PDCD6,GOLGA2,CEP55,XIAP,TFG,DAZAP2,APP,TACC3,WWP2 |
| 1.524e-02 | -4.18 | GYS1 (glycogen synthase 1) | protein interactions | 2997 | 34 | 11 | 17029 | 2761 |
OTUD5,PPP1R3B,PRKAB1,CSNK2A1,CUL1,SIRT2,GYG1,PRKACA,APP,WWP2,EVC2 |
| 1.524e-02 | -4.18 | PPIH (peptidylprolyl isomerase H) | protein interactions | 10465 | 34 | 11 | 17029 | 2761 |
RPL32,LSM6,HUWE1,WDR1,CUL3,OLA1,LSM8,PRPF4,PRPF3,PRPF18,N4BP2L2 |
| 1.524e-02 | -4.18 | YTHDC2 (YTH domain containing 2) | protein interactions | 64848 | 34 | 11 | 17029 | 2761 |
IRF4,NIFK,ZNF512,RPS14,USP42,CUL3,TARDBP,IFI16,SRPK2,CAND1,DCTN1 |
| 1.524e-02 | -4.18 | PTP4A2 (protein tyrosine phosphatase type IVA, member 2) | protein interactions | 8073 | 34 | 11 | 17029 | 2761 |
PON2,UNK,FNTA,TNFAIP8,PRDX3,PTP4A3,EFL1,USF2,CNNM3,RPL22L1,SPTAN1 |
| 1.525e-02 | -4.18 | GO_REGULATION_OF_EXTRINSIC_APOPTOTIC_SIGNALING_PATHWAY | MSigDB lists | GO_REGULATION_OF_EXTRINSIC_APOPTOTIC_SIGNALING_PATHWAY | 150 | 33 | 17377 | 2626 |
GCLM,CYLD,NF1,EYA1,RAF1,BCL2L1,PARK7,LMNA,CFLAR,SP100,PTEN,DAPK1,FEM1B,ARHGEF2,BCL2,TMBIM1,HTRA2,ACSL5,TNFAIP3,RB1CC1,ZMYND11,RFFL,MCL1,BRCA1,DAPK3,FADD,FAS,HSPA1B,SIAH2,PML,HMGB2,ZC3HC1,FAF1 |
| 1.525e-02 | -4.18 | GSE13485_CTRL_VS_DAY7_YF17D_VACCINE_PBMC_UP | MSigDB lists | GSE13485_CTRL_VS_DAY7_YF17D_VACCINE_PBMC_UP | 161 | 35 | 17377 | 2626 |
POU3F2,CDS2,TOMM20,ST13,SYS1,RPLP2,KLHL21,GPBP1L1,RAF1,NACA,EIF3D,TKT,LAMTOR3,SDC2,COX4I1,PABPC4,RPL11,ITGB8,TBC1D14,MRPS27,FBL,TOP1MT,PCBP2,ZDHHC18,PPP3CA,CELSR2,RPL6,UBE4B,FXR1,SLC25A5,EIF3H,QARS,BTF3,ZNF830,PTDSS1 |
| 1.526e-02 | -4.18 | KEGG_FC_GAMMA_R_MEDIATED_PHAGOCYTOSIS | MSigDB lists | KEGG_FC_GAMMA_R_MEDIATED_PHAGOCYTOSIS | 91 | 22 | 17377 | 2626 |
WASF2,AKT2,RAF1,VAV2,RAC1,ARPC1A,LYN,MAPK3,PIP5K1C,CRKL,VAV1,VASP,WAS,ASAP2,CDC42,ARPC5,LIMK1,PIK3R2,DNM2,PIKFYVE,MAPK1,CFL1 |
| 1.526e-02 | -4.18 | GAK (cyclin G associated kinase) | protein interactions | 2580 | 90 | 23 | 17029 | 2761 |
USO1,SEC16A,EDRF1,APP,PICALM,XPR1,CDK5,INF2,CHMP4A,HSPBP1,SEC24C,AXIN1,IARS2,AP1M1,GTSE1,FEM1B,AP2B1,DMWD,CLTB,PARP10,PHKG2,NUMB,SPTAN1 |
| 1.530e-02 | -4.18 | JIANG_HYPOXIA_NORMAL | MSigDB lists | JIANG_HYPOXIA_NORMAL | 297 | 59 | 17377 | 2626 |
SLC30A9,TOMM20,C19orf53,MUT,UGP2,GXYLT1,GNPDA1,ADAM10,TSC22D3,ZFP91,SLC2A1,ALKBH5,AP3M2,PLAGL2,MYH9,SIKE1,IKBIP,C2orf49,MAP1LC3B,KCMF1,MOAP1,CSDE1,ADD3,EIF2S2,NEK6,MED10,CDC42,GRSF1,ARHGEF1,ARHGEF2,AP2B1,CORO1A,TFG,CITED2,GM2A,RYBP,CPNE1,RPL29,STAU1,SGCE,DCAF6,ELL2,C1orf35,MCL1,ARPC1A,KLF6,PI4K2A,NAP1L1,SERTAD2,KPNA4,AGPAT2,MAGT1,PTER,GADD45B,PPP1R11,YWHAZ,H3F3A,CHPT1,RNF114 |
| 1.534e-02 | -4.18 | well_differentiated | COSMIC cancer mutations | well_differentiated | 11 | 5 | 17385 | 2587 |
KRAS,FUS,EWSR1,NRAS,HRAS |
| 1.534e-02 | -4.18 | haematopoietic_and_lymphoid_tissue-lymph_node-lymphoid_neoplasm-B_cell_lymphoma_unspecified | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-lymph_node-lymphoid_neoplasm-B_cell_lymphoma_unspecified | 11 | 5 | 17385 | 2587 |
KRAS,NRAS,PTEN,HRAS,CDKN2A |
| 1.534e-02 | -4.18 | seborrhoeic_keratosis | COSMIC cancer mutations | seborrhoeic_keratosis | 11 | 5 | 17385 | 2587 |
FGFR3,PTEN,HRAS,CDKN2A,PTPN11 |
| 1.534e-02 | -4.18 | skin-back-malignant_melanoma-superficial_spreading | COSMIC cancer mutations | skin-back-malignant_melanoma-superficial_spreading | 11 | 5 | 17385 | 2587 |
KRAS,STK11,NRAS,HRAS,CDKN2A |
| 1.534e-02 | -4.18 | upper_aerodigestive_tract-mouth-other-dysplasia | COSMIC cancer mutations | upper_aerodigestive_tract-mouth-other-dysplasia | 11 | 5 | 17385 | 2587 |
KRAS,NRAS,SF3B1,HRAS,CDKN2A |
| 1.534e-02 | -4.18 | small_intestine-ileum-carcinoid-endocrine_tumour | COSMIC cancer mutations | small_intestine-ileum-carcinoid-endocrine_tumour | 11 | 5 | 17385 | 2587 |
KRAS,NRAS,MEN1,HRAS,SMAD4 |
| 1.534e-02 | -4.18 | central_nervous_system-temporal_lobe-glioma-astrocytoma_Grade_III | COSMIC cancer mutations | central_nervous_system-temporal_lobe-glioma-astrocytoma_Grade_III | 11 | 5 | 17385 | 2587 |
KRAS,NF1,CDKN2A,MSH6,MSH2 |
| 1.534e-02 | -4.18 | retromolar | COSMIC cancer mutations | retromolar | 11 | 5 | 17385 | 2587 |
KRAS,NRAS,PTEN,HRAS,CDKN2A |
| 1.534e-02 | -4.18 | oncocytoma | COSMIC cancer mutations | oncocytoma | 11 | 5 | 17385 | 2587 |
FGFR3,KRAS,NRAS,VHL,HRAS |
| 1.534e-02 | -4.18 | adrenal_gland-adrenal_gland-adrenal_cortical_hyperplasia | COSMIC cancer mutations | adrenal_gland-adrenal_gland-adrenal_cortical_hyperplasia | 11 | 5 | 17385 | 2587 |
GNAS,KRAS,NRAS,MEN1,HRAS |
| 1.534e-02 | -4.18 | soft_tissue-fat-liposarcoma-well_differentiated | COSMIC cancer mutations | soft_tissue-fat-liposarcoma-well_differentiated | 11 | 5 | 17385 | 2587 |
KRAS,FUS,EWSR1,NRAS,HRAS |
| 1.534e-02 | -4.18 | congenital | COSMIC cancer mutations | congenital | 11 | 5 | 17385 | 2587 |
FGFR3,KRAS,NRAS,HRAS,CDKN2A |
| 1.534e-02 | -4.18 | central_nervous_system-spinal_cord-glioma-astrocytoma_Grade_I | COSMIC cancer mutations | central_nervous_system-spinal_cord-glioma-astrocytoma_Grade_I | 11 | 5 | 17385 | 2587 |
KRAS,NRAS,PTEN,HRAS,CDKN2A |
| 1.534e-02 | -4.18 | skin-back-benign_melanocytic_nevus | COSMIC cancer mutations | skin-back-benign_melanocytic_nevus | 11 | 5 | 17385 | 2587 |
KRAS,STK11,NRAS,HRAS,CDKN2A |
| 1.534e-02 | -4.18 | kidney-other-oncocytoma | COSMIC cancer mutations | kidney-other-oncocytoma | 11 | 5 | 17385 | 2587 |
FGFR3,KRAS,NRAS,VHL,HRAS |
| 1.534e-02 | -4.18 | central_nervous_system-cerebellum-glioma-astrocytoma_Grade_IV | COSMIC cancer mutations | central_nervous_system-cerebellum-glioma-astrocytoma_Grade_IV | 11 | 5 | 17385 | 2587 |
KRAS,H3F3A,HRAS,MSH6,MSH2 |
| 1.534e-02 | -4.18 | central_nervous_system-cerebellum-glioma-astrocytoma_Grade_III | COSMIC cancer mutations | central_nervous_system-cerebellum-glioma-astrocytoma_Grade_III | 11 | 5 | 17385 | 2587 |
KRAS,H3F3A,CDKN2A,MSH6,MSH2 |
| 1.534e-02 | -4.18 | soft_tissue-fibrous_tissue_and_uncertain_origin-sarcoma-spindle | COSMIC cancer mutations | soft_tissue-fibrous_tissue_and_uncertain_origin-sarcoma-spindle | 11 | 5 | 17385 | 2587 |
KRAS,FUS,EWSR1,PTEN,CDKN2A |
| 1.534e-02 | -4.18 | skin-foot-malignant_melanoma-nodular | COSMIC cancer mutations | skin-foot-malignant_melanoma-nodular | 11 | 5 | 17385 | 2587 |
KRAS,NRAS,PTEN,HRAS,CDKN2A |
| 1.534e-02 | -4.18 | bone-extraskeletal-chondrosarcoma-myxoid | COSMIC cancer mutations | bone-extraskeletal-chondrosarcoma-myxoid | 11 | 5 | 17385 | 2587 |
TCF12,FUS,EWSR1,TFG,PTEN |
| 1.538e-02 | -4.17 | RGAANNTTC_V$HSF1_01 | MSigDB lists | RGAANNTTC_V$HSF1_01 | 414 | 79 | 17377 | 2626 |
RORB,CYLD,H2AFZ,ST13,PLXNC1,TRERF1,LUZP1,TRIP10,MAPK14,CHD1,BCAP31,ARL6IP6,CREM,ZER1,ANKRD28,HNRNPA2B1,NRF1,AHCTF1,NEK6,SYNM,IL6ST,ABCC5,USP34,CCT2,LAP3,TLK1,MAP4K4,E2F3,DNAJA1,GIGYF1,MAT2A,RHBDF2,SRSF1,DDX17,ALKBH6,KRIT1,VEZF1,EIF4ENIF1,TAB2,OGT,SMAD1,HSPH1,MAGEH1,B4GALT5,CCM2,LAMTOR3,JMJD6,DNAJB1,XPNPEP3,PSEN1,RGS1,ATG4A,PIP5K1C,NFATC3,SSBP3,DAPK1,TNPO3,MDFIC,ABCD1,KNTC1,PIKFYVE,ELOVL5,DENND1B,ATP2C1,KCNQ1,PLEC,ZP3,EIF4G2,CCT8,PHF6,HSPA1B,CBX3,GNAS,DERL1,HLA-B,ZNF777,DBI,RBPJ,PURA |
| 1.539e-02 | -4.17 | GO_LYSINE_N_METHYLTRANSFERASE_ACTIVITY | MSigDB lists | GO_LYSINE_N_METHYLTRANSFERASE_ACTIVITY | 41 | 12 | 17377 | 2626 |
IRF4,ASH1L,SUV39H2,CXXC1,SETD3,CAMKMT,EHMT1,WDR82,EZH1,MEN1,WDR5,DOT1L |
| 1.539e-02 | -4.17 | NAKAYAMA_FRA2_TARGETS | MSigDB lists | NAKAYAMA_FRA2_TARGETS | 41 | 12 | 17377 | 2626 |
MDM2,YTHDF3,WIPF1,DNAJB1,RGS2,SOX4,ZFAND5,SLC20A1,F2R,STK17B,ZMAT3,SPSB3 |
| 1.539e-02 | -4.17 | GROSS_HYPOXIA_VIA_ELK3_ONLY_DN | MSigDB lists | GROSS_HYPOXIA_VIA_ELK3_ONLY_DN | 41 | 12 | 17377 | 2626 |
CDKN2C,TRIM8,PDRG1,EI24,KIF23,RACGAP1,CDC25B,CHEK2,NDE1,MINPP1,MAPK14,STMN1 |
| 1.542e-02 | -4.17 | HAUS2 (HAUS augmin like complex subunit 2) | protein interactions | 55142 | 95 | 24 | 17029 | 2761 |
SCAMP3,RPL38,MOGS,HAUS4,TRIM28,SDE2,STOML2,HAUS8,MTFR1L,DAP3,PCM1,PDCD6,STT3A,CCDC14,MAPK6,LRPPRC,SRI,MRPS27,SASS6,SMARCE1,PHKG2,POC5,TUBB,PDF |
| 1.542e-02 | -4.17 | IPO7 (importin 7) | protein interactions | 10527 | 95 | 24 | 17029 | 2761 |
UNK,KARS,STAU1,HARS,ASPM,NUSAP1,BRCA1,CAPZA2,MCM2,RPL23A,CAND1,PFDN5,MDM2,PPM1G,NUP107,NUP153,RP2,RNASEH2A,CDK2,IGBP1,IFI16,CDC5L,HP1BP3,DCTN1 |
| 1.548e-02 | -4.17 | ubiquitinyl hydrolase activity | molecular function | GO:0101005 | 121 | 28 | 17224 | 2647 |
OTUD5,USP7,ATXN3,CYLD,KAT2A,TNFAIP3,USP42,USP39,USP10,OTUD3,USP22,USP48,USP21,WDR48,USP36,USP5,ANKZF1,UCHL5,TANK,USP32,USP20,VCPIP1,JOSD1,USP11,ZRANB1,USP53,USP13,USP34 |
| 1.548e-02 | -4.17 | thiol-dependent ubiquitinyl hydrolase activity | molecular function | GO:0036459 | 121 | 28 | 17224 | 2647 |
USP7,OTUD5,CYLD,ATXN3,TNFAIP3,KAT2A,USP42,USP39,USP10,OTUD3,USP22,USP48,USP21,USP36,WDR48,USP5,ANKZF1,UCHL5,TANK,USP32,USP20,VCPIP1,JOSD1,USP11,ZRANB1,USP53,USP34,USP13 |
| 1.551e-02 | -4.17 | UBQLN4 (ubiquilin 4) | protein interactions | 56893 | 187 | 42 | 17029 | 2761 |
PPIB,IMMT,MIF4GD,ANKRD13D,TXN,SRGN,UBXN1,ADPGK,UBQLN2,FKBP2,OAT,DAZAP2,STMN1,STAM,RAD23A,MOAP1,RPN1,PSMD2,MDM2,PIN1,RAD23B,TTC9C,ZBTB22,CYB5R1,MYDGF,AHCYL1,KDELR1,USP34,UBQLN4,ATP5IF1,PBXIP1,RNPS1,ATXN1,SUPT20H,ZDHHC3,HGS,ITPRIPL1,PRDX3,CCDC14,TRIM32,KLHL42,UBE2C |
| 1.552e-02 | -4.17 | Snf7 | pfam domains | PF03357 | 11 | 5 | 17054 | 2545 |
CHMP4B,CHMP2A,CHMP4A,CHMP2B,CHMP7 |
| 1.553e-02 | -4.16 | NMD3 (NMD3 ribosome export adaptor) | protein interactions | 51068 | 66 | 18 | 17029 | 2761 |
LARS,TRMT6,GTPBP4,LNX2,CSNK2A1,MAT2A,MAPK3,EPRS,HSPBP1,AHSA1,RAD23B,MSH2,CTPS1,FAM83D,STAT1,RRS1,PFKP,CSTF1 |
| 1.553e-02 | -4.16 | CCTGTGA,MIR-513 | MSigDB lists | CCTGTGA,MIR-513 | 123 | 28 | 17377 | 2626 |
GGNBP2,EYA1,YTHDF3,SNN,DCUN1D4,PRMT2,PPP1R16B,USP21,SERP1,DDRGK1,LRRC14,CALM2,PPP1R3B,ADD3,CLK3,DPYSL2,LUC7L3,CSNK1G1,FIZ1,OGT,EI24,CRY2,MBD6,WIPI2,FAM76B,PDXK,PPP6R3,PURA |
| 1.553e-02 | -4.16 | GSE13522_CTRL_VS_T_CRUZI_Y_STRAIN_INF_SKIN_BALBC_MOUSE_UP | MSigDB lists | GSE13522_CTRL_VS_T_CRUZI_Y_STRAIN_INF_SKIN_BALBC_MOUSE_UP | 123 | 28 | 17377 | 2626 |
SRM,PTMS,SARNP,FAM118B,EIF3D,SLC2A1,CENPF,LDHA,SSR2,HMGN3,POMP,TOMM40,TSR2,POLR3K,CLNS1A,PSMC4,GNA12,ERH,SURF4,SCAP,MRPS27,PDCD2,CABLES2,ERI3,LRRC59,RPS26,MLST8,EGLN1 |
| 1.553e-02 | -4.16 | FANCD2 (Fanconi anemia complementation group D2) | protein interactions | 2177 | 100 | 25 | 17029 | 2761 |
PRKDC,TOP3A,BRCA1,CNTROB,MEN1,BLM,MCM2,FANCE,FOXO3,FANCI,RPA1,FANCL,PCNA,KPNA1,RAD18,CDC42,MCM5,UHRF2,MSH2,H2AFX,ATP5F1A,TERF1,IPO4,CDC5L,SPTAN1 |
| 1.555e-02 | -4.16 | Pkinase | pfam domains | PF00069 | 348 | 67 | 17054 | 2545 |
RPS6KA1,CSNK2A1,MAPK14,PRKACA,CDK5,PRKD3,NEK6,MAST2,SCYL3,CDK12,SRPK2,PLK1,PLK3,ULK3,AKT2,PBK,TLK1,TAOK1,MAP4K4,AURKB,PKMYT1,STK17B,MAP3K4,MKNK1,CLK3,STK38,HIPK2,STK11,CHEK2,ROCK1,RNASEL,MAPK1,CSNK1D,PRPF4B,PRKAA1,TRIO,SCYL1,CDK13,EIF2AK4,CDK11B,CSNK1A1,SCYL2,GRK2,DAPK1,MAP3K14,PHKG2,CSNK1G3,CAMK2G,PDPK1,CSNK1G2,MAPKAPK3,NEK7,MAP4K3,EIF2AK1,MAP2K2,MARK2,CDK11A,DAPK3,MASTL,MAPK3,NEK1,CSNK1G1,MAPK6,MAP3K5,RPS6KC1,CDK2,HIPK3 |
| 1.555e-02 | -4.16 | GSE15330_LYMPHOID_MULTIPOTENT_VS_MEGAKARYOCYTE_ERYTHROID_PROGENITOR_DN | MSigDB lists | GSE15330_LYMPHOID_MULTIPOTENT_VS_MEGAKARYOCYTE_ERYTHROID_PROGENITOR_DN | 189 | 40 | 17377 | 2626 |
SRM,UBE2E2,GNPNAT1,TRIP10,ADAM10,PHB2,RPS6KA1,OAT,STMN1,BZW2,CD320,ADD3,PIN1,PPCDC,BRI3,PABPC1,TIMM50,CDC37,EBAG9,ACSL5,CPNE1,DDX24,AATF,TNFAIP3,ANKRD33B,RNF25,LNX2,MTX1,NFATC2IP,HERPUD2,LUC7L,MRPS14,EPB41,SLC19A1,CDKN2AIPNL,STAT6,SIAH2,COX5A,RUVBL2,PRPF4B |
| 1.555e-02 | -4.16 | GSE29618_BCELL_VS_MONOCYTE_DN | MSigDB lists | GSE29618_BCELL_VS_MONOCYTE_DN | 189 | 40 | 17377 | 2626 |
RHOG,GMFG,CAST,NOTCH2,ATP6V1B2,GNS,FKBP1A,CAPN2,SEC11A,CTSS,DPYSL2,DAPK1,CS,H2AFY,ANXA5,METTL9,S100A6,AMPD2,CYFIP1,FTL,RHOA,CREG1,SELPLG,CAPZA2,PTTG1IP,ZFAND5,PICALM,MYO1F,TPD52L2,ALDH3B1,RBM47,ADAM9,ZDHHC7,CTSA,ATP6V0C,PSAP,ZMIZ1,LTA4H,RTN3,OAZ1 |
| 1.555e-02 | -4.16 | GSE7509_DC_VS_MONOCYTE_WITH_FCGRIIB_STIM_DN | MSigDB lists | GSE7509_DC_VS_MONOCYTE_WITH_FCGRIIB_STIM_DN | 189 | 40 | 17377 | 2626 |
ZNF207,RAB14,B4GALT5,ARID5A,XIAP,LYN,BIRC2,PTPN2,ABL2,SP100,RALB,RABGAP1L,RBM34,ETV6,SRSF4,FBXO7,PPP4R1,ZNF200,CLDND1,TRIM14,CGGBP1,BAK1,TRAFD1,NASP,DRAP1,AMD1,MTMR6,DNAJA1,MACF1,STK17B,ISG15,DHX15,FAS,RBMS1,NUP62,ATF6,RBPJ,RGL1,H3F3A,ZC3HAV1 |
| 1.555e-02 | -4.16 | GSE17721_LPS_VS_PAM3CSK4_4H_BMDC_UP | MSigDB lists | GSE17721_LPS_VS_PAM3CSK4_4H_BMDC_UP | 189 | 40 | 17377 | 2626 |
OTUD5,TOR3A,TRIO,GTF2F1,PHC2,PTPN2,RAB8A,PCNA,CLIC4,SIAH1,ARL6IP1,AXIN2,TCEA1,PLCL2,HTRA2,MORC3,VOPP1,MND1,PHF20L1,ATP13A1,POLR2G,TNFAIP3,BTG2,DNAJA1,OGFR,PSMB9,ARF4,ATP6V1D,SEC23IP,PDLIM1,CDC27,ELMO1,HIPK2,IMPDH1,HMGB2,NAA20,SMAD1,RUFY3,PLOD3,RNF114 |
| 1.555e-02 | -4.16 | GSE45365_NK_CELL_VS_CD8_TCELL_MCMV_INFECTION_DN | MSigDB lists | GSE45365_NK_CELL_VS_CD8_TCELL_MCMV_INFECTION_DN | 189 | 40 | 17377 | 2626 |
TXN,H2AFZ,ANXA6,TRIP10,SRGN,TAP1,ENSA,MED13L,TBC1D13,CHKB,SND1,SNN,TWF2,PPP1R16B,RAB11A,TANK,TNPO2,NAP1L4,MAP3K14,MVP,CSNK1G3,HTRA2,GPX4,TRAFD1,DCAF6,SEC61B,BIRC3,PRIM2,ETV3,TNFAIP3,MAP4K4,RAB5B,PSMC4,KIF2A,CERS6,GADD45B,LY75,SMG9,CLU,USP11 |
| 1.555e-02 | -4.16 | GSE40666_NAIVE_VS_EFFECTOR_CD8_TCELL_WITH_IFNA_STIM_90MIN_UP | MSigDB lists | GSE40666_NAIVE_VS_EFFECTOR_CD8_TCELL_WITH_IFNA_STIM_90MIN_UP | 189 | 40 | 17377 | 2626 |
GMFG,SCAMP3,RHOC,FAM129A,TMX4,AP3M2,C5orf30,STARD7,SIKE1,DAZAP2,CRLF3,APP,FBXO22,DDRGK1,FANCL,RAB21,PDCD10,THADA,FOXN2,CNN2,GPD1L,F2R,GM2A,S100A6,EBAG9,RAB7A,SELPLG,RPL6,EMP3,NLN,CAPZA2,ADRB2,PSMB9,IRF5,AHNAK,STK38,ACBD4,MYL12B,PDCD4,ESYT2 |
| 1.555e-02 | -4.16 | GSE22935_WT_VS_MYD88_KO_MACROPHAGE_48H_MBOVIS_BCG_STIM_DN | MSigDB lists | GSE22935_WT_VS_MYD88_KO_MACROPHAGE_48H_MBOVIS_BCG_STIM_DN | 189 | 40 | 17377 | 2626 |
ZCCHC9,LUZP1,DAP,RHOC,ACTR3,TRIO,MED13L,CHIC2,TMEM165,ANKIB1,PIP4K2A,CMTM6,KIAA1147,KIFC1,TNFAIP8,RAB35,SRI,NOC2L,MDFIC,ALDH18A1,MOB1A,RNF169,KDELR1,ADCY7,PLK3,TNFAIP3,TSPAN31,WIPF1,WDR82,GALNT7,KLF6,PICALM,MAPK3,SEC61A1,CERS6,CSK,CORO1C,PITPNA,PKD2,REEP4 |
| 1.556e-02 | -4.16 | CDC42 (cell division cycle 42) | protein interactions | 998 | 224 | 49 | 17029 | 2761 |
WASF2,RAB14,UNK,GOLIM4,PNISR,ST13,RAB11B,TRIP10,MECP2,ACTR3,CBLL1,CDC42SE2,NOTCH2,STMN1,BIRC2,KTN1,MIEF1,VAV1,FARSA,RAP1A,ZNF420,NEK6,CDC42,ARPC5,DUT,SEC24C,GTSE1,ARHGAP17,STAU1,LARS,PGGT1B,WIPF1,ARHGDIB,MCM2,RAB1A,PRDX1,MAP3K4,DNAJC10,EPRS,WAS,AHNAK,PRDX3,BBX,MYO9A,ARRB2,ABCA1,DEF6,PARD3,IFI16 |
| 1.557e-02 | -4.16 | SAMD1 (sterile alpha motif domain containing 1) | protein interactions | 90378 | 52 | 15 | 17029 | 2761 |
KIF18A,CDC16,UPF1,PDCD6,TRIP10,L3MBTL3,NSMCE2,XIAP,CBWD1,TOR1AIP2,RBPJ,CDIPT,PRMT2,TRIM14,IWS1 |
| 1.557e-02 | -4.16 | SEC31A (SEC31 homolog A, COPII coat complex component) | protein interactions | 22872 | 52 | 15 | 17029 | 2761 |
TPD52L2,SEC23IP,ATP6V1D,SAR1A,TSTA3,NSF,GNPDA1,SCYL1,CUL3,ARMT1,BRCA1,TFG,ATP6V1C1,STAM,DHX15 |
| 1.557e-02 | -4.16 | NIPSNAP2 (nipsnap homolog 2) | protein interactions | 2631 | 52 | 15 | 17029 | 2761 |
PPP1R3B,PA2G4,LARS,KEAP1,PRKDC,MTA2,CUL3,NDUFA4,MAP1LC3B,DDX39A,FOXO3,TARS,PFKP,ALDH9A1,NIPSNAP1 |
| 1.557e-02 | -4.16 | CNOT7 (CCR4-NOT transcription complex subunit 7) | protein interactions | 29883 | 52 | 15 | 17029 | 2761 |
CNOT9,MEX3C,BTG2,GADD45B,AGO2,CNOT6,CAPZA2,CNTROB,CNOT6L,CDK2,CNOT11,PABPC1,TOB1,APP,CNOT3 |
| 1.557e-02 | -4.16 | SMARCD2 (SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2) | protein interactions | 6603 | 52 | 15 | 17029 | 2761 |
PCM1,KPNA1,CUL3,BCL7C,BAZ1B,SMARCA4,TOP2B,UPF2,NUP153,NFATC2,BRCA1,ARID1A,SMARCE1,ARID1B,SMARCD1 |
| 1.557e-02 | -4.16 | SORBS2 (sorbin and SH3 domain containing 2) | protein interactions | 8470 | 52 | 15 | 17029 | 2761 |
AFDN,ABL2,MDM2,MAPRE1,WAS,AKT2,SUZ12,MYO18A,DLGAP4,FLOT1,MYH9,YWHAZ,CAPZA2,PKM,ANLN |
| 1.557e-02 | -4.16 | ZCCHC8 (zinc finger CCHC-type containing 8) | protein interactions | 55596 | 52 | 15 | 17029 | 2761 |
RPA2,USP7,EXOSC7,THOC1,EXOSC1,CUL3,GBA,HNRNPF,PSMA1,BRCA1,LUC7L,PPP2R2D,APP,PSMC4,RPA1 |
| 1.557e-02 | -4.16 | ANAPC4 (anaphase promoting complex subunit 4) | protein interactions | 29945 | 52 | 15 | 17029 | 2761 |
KIF18A,CDC16,CCNA2,CDC27,PTEN,PSMD8,C16orf87,RRM2,ANAPC2,KRAS,ANAPC7,CDC23,CCNB1,ANAPC4,FBXO5 |
| 1.557e-02 | -4.16 | BCL7A (BCL tumor suppressor 7A) | protein interactions | 605 | 52 | 15 | 17029 | 2761 |
PHF10,ARID2,CUL3,BCL7C,BRD7,SMARCA4,NSD3,ARID1A,INO80E,PBRM1,TWF2,BRD9,SMARCE1,ARID1B,SMARCD1 |
| 1.557e-02 | -4.16 | ATG16L1 (autophagy related 16 like 1) | protein interactions | 55054 | 52 | 15 | 17029 | 2761 |
CCT2,HSPA4,SCOC,RB1CC1,ATG3,RAB35,ATG13,WIPI2,PMF1,IKBIP,MAP1LC3B,APP,SNAPC4,DVL2,OPTN |
| 1.559e-02 | -4.16 | CDK8 (cyclin dependent kinase 8) | protein interactions | 1024 | 105 | 26 | 17029 | 2761 |
CCNC,CTDP1,PPP1R12A,DENND4C,SUZ12,HNRNPF,MED13L,SMARCA4,BRCA1,THRAP3,BUD13,SUPT7L,RBM4,POLR2A,GTF2F1,GEMIN5,SMAD2,SMC3,MED8,MED10,STK38,MED15,TCEA1,SMAD1,MAML1,MED22 |
| 1.559e-02 | -4.16 | human chr5q12.3 | chromosome location | human chr5q12.3 | 20 | 6 | 26185 | 2809 |
NLN,SREK1,TRAPPC13,PPWD1,ERBIN,CWC27 |
| 1.561e-02 | -4.16 | salivary_gland-carcinoma-adenocarcinoma | COSMIC cancer mutations | salivary_gland-carcinoma-adenocarcinoma | 19 | 7 | 17385 | 2587 |
KRAS,STK11,NRAS,PTEN,HRAS,SMAD4,ETV6 |
| 1.561e-02 | -4.16 | small_intestine-ileum-carcinoma-adenocarcinoma | COSMIC cancer mutations | small_intestine-ileum-carcinoma-adenocarcinoma | 19 | 7 | 17385 | 2587 |
GNAS,KRAS,STK11,NRAS,SMAD4,CDKN2A,PTPN11 |
| 1.561e-02 | -4.16 | malignant_adnexal_tumour | COSMIC cancer mutations | malignant_adnexal_tumour | 19 | 7 | 17385 | 2587 |
FGFR3,KRAS,CYLD,NRAS,PTEN,HRAS,CDKN2A |
| 1.562e-02 | -4.16 | GO_RESPONSE_TO_HYDROGEN_PEROXIDE | MSigDB lists | GO_RESPONSE_TO_HYDROGEN_PEROXIDE | 107 | 25 | 17377 | 2626 |
BAK1,PPIF,TNFAIP3,NET1,PPP1R15B,PRKAA1,LDHA,KLF6,ETS1,PARK7,RHOB,FAS,CAT,KPNA4,MDM2,PDCD10,SHC1,PRDX3,STAT6,AKR1B1,ADAM9,BCL2,MAP3K5,PPP5C,HDAC2 |
| 1.562e-02 | -4.16 | GCTTGAA,MIR-498 | MSigDB lists | GCTTGAA,MIR-498 | 107 | 25 | 17377 | 2626 |
FYTTD1,PPP3CA,MAPRE1,C16orf72,MECP2,TSC22D3,SREK1,RAB6A,CAPZA2,ZNF518A,RAB11A,RAB22A,EML4,TFRC,ATPAF1,PHF6,ANKRD28,TMED10,SS18L1,NCOA1,ST8SIA2,PDIA6,CBX4,CAMK2G,SRSF10 |
| 1.566e-02 | -4.16 | SASSON_RESPONSE_TO_GONADOTROPHINS_UP | MSigDB lists | SASSON_RESPONSE_TO_GONADOTROPHINS_UP | 86 | 21 | 17377 | 2626 |
SRP72,RAB14,TK1,ACP2,TNFAIP3,JMJD6,CREBL2,RAB1A,ARPC1A,MAP1LC3B,RHOB,GNAS,PTPRF,PSMD1,DUSP3,RAB4A,PGRMC1,FKBP5,ACTB,PDXK,MAP3K5 |
| 1.566e-02 | -4.16 | MORI_MATURE_B_LYMPHOCYTE_UP | MSigDB lists | MORI_MATURE_B_LYMPHOCYTE_UP | 86 | 21 | 17377 | 2626 |
YTHDC1,ADD1,GNPNAT1,MCL1,ADRB2,GGA2,C19orf48,ETS1,MACF1,RMI1,CMTM6,PIP4K2A,SMAP2,MAN1A1,RAB8A,CTSS,TBC1D14,FAM76B,CNOT6L,ABCA1,ADCY7 |
| 1.566e-02 | -4.16 | GO_LYSOSOMAL_LUMEN | MSigDB lists | GO_LYSOSOMAL_LUMEN | 86 | 21 | 17377 | 2626 |
ACP2,AGRN,GALC,PPT1,MANBA,HEXB,SDC2,GBA,ASAH1,MAN2B1,GYG1,NEU1,GNS,SCARB2,SGSH,CTSS,NAGLU,CTSA,PSAP,HEXA,GM2A |
| 1.566e-02 | -4.16 | NAKAYAMA_SOFT_TISSUE_TUMORS_PCA2_UP | MSigDB lists | NAKAYAMA_SOFT_TISSUE_TUMORS_PCA2_UP | 86 | 21 | 17377 | 2626 |
HJURP,ASPM,PBK,CENPF,TPX2,MKI67,CDCA8,RRM2,NUSAP1,KIF2C,CCNB1,KIF11,FGFR3,CCNA2,BIRC5,PITX1,CEP55,GTSE1,UBE2C,CCNB2,ESPL1 |
| 1.572e-02 | -4.15 | Anticodon-bd_dom_sf | interpro domains | IPR036621 | 11 | 5 | 18492 | 2768 |
EPRS,EIF2AK4,POLG2,HARS,TARS |
| 1.572e-02 | -4.15 | Snf7_fam | interpro domains | IPR005024 | 11 | 5 | 18492 | 2768 |
CHMP2A,CHMP4B,CHMP4A,CHMP2B,CHMP7 |
| 1.575e-02 | -4.15 | positive regulation of binding | biological process | GO:0051099 | 166 | 36 | 17256 | 2622 |
TXN,MAPRE1,ADD1,EIF3D,CDT1,DHX9,FLOT1,SIRT2,STMN1,PSEN1,PARK7,APP,DDRGK1,RPL11,CDK5,FKBP1A,RB1,IRF4,RALB,MBD2,PLCL2,TGFB1,KAT2A,MFNG,EDF1,MEN1,TRIM28,EPB41,KRIT1,DERL1,PPP2CA,HIPK2,CEBPG,HMGB2,TICAM1,NMD3 |
| 1.577e-02 | -4.15 | GSE17974_CTRL_VS_ACT_IL4_AND_ANTI_IL12_2H_CD4_TCELL_DN | MSigDB lists | GSE17974_CTRL_VS_ACT_IL4_AND_ANTI_IL12_2H_CD4_TCELL_DN | 178 | 38 | 17377 | 2626 |
CHMP2A,PIGM,CYTIP,IMMT,TP53RK,MRPL42,GNPNAT1,GNPDA1,CYCS,CHAC2,FBXO22,COPB2,UTP18,SLC26A2,TMBIM1,COPS8,JMJD4,KLF10,NSDHL,ERLIN1,CRNKL1,RABIF,SLC17A5,TOLLIP,GAR1,FADD,PRDX1,SRSF1,MTHFD2,ORMDL2,TTLL4,MFAP1,PSMD8,DNAJC17,CENPBD1,PDCD2L,BYSL,GPATCH4 |
| 1.577e-02 | -4.15 | GSE7219_WT_VS_NIK_NFKB2_KO_DC_UP | MSigDB lists | GSE7219_WT_VS_NIK_NFKB2_KO_DC_UP | 178 | 38 | 17377 | 2626 |
GPR132,TMEM184B,FAM129A,ARID5A,TMEM97,NKRF,DNAJB1,IL21R,MXD1,RGS1,JMY,PRNP,CLIC4,MEX3C,SNX18,IL6ST,ZCCHC2,STAT3,NCOA2,PLK3,TRAFD1,KLF10,AMD1,KIF11,ARL5B,RHOB,SERTAD2,ATAD2,ETS2,BRD2,GADD45B,NFIL3,STAT1,H2AFX,RBPJ,TOB1,CBX4,CWC25 |
| 1.577e-02 | -4.15 | GSE30971_CTRL_VS_LPS_STIM_MACROPHAGE_WBP7_HET_2H_DN | MSigDB lists | GSE30971_CTRL_VS_LPS_STIM_MACROPHAGE_WBP7_HET_2H_DN | 178 | 38 | 17377 | 2626 |
RMND5A,REPS2,KIAA0232,TMEM97,GLUD1,GGA2,ITGB5,PIP4K2A,GTF2F1,C12orf10,SLC31A1,PARL,CISD2,RNF135,RBM15,IMPA2,DRAM2,TRIM14,TIMM8B,GALC,TACC1,PPT1,DRAP1,DENND1B,MFNG,FBXO9,ABHD11,RHOT1,MACF1,HHEX,PON2,SCARB2,TMED10,ZDHHC7,SNRPG,WDR91,LTA4H,RNF114 |
| 1.577e-02 | -4.15 | GSE32034_UNTREATED_VS_ROSIGLIZATONE_TREATED_LY6C_HIGH_MONOCYTE_DN | MSigDB lists | GSE32034_UNTREATED_VS_ROSIGLIZATONE_TREATED_LY6C_HIGH_MONOCYTE_DN | 178 | 38 | 17377 | 2626 |
RMND5A,SUCLG1,RBM8A,MRPS26,SPR,EIF1B,LYRM2,BCAP31,CHKA,TMEM179B,MAT2B,MDM2,RBM3,TARDBP,MRPL11,ARL5A,RPAP3,ZFP64,EID1,RPL6,MRPL43,UHRF1BP1,DIDO1,KDM3A,SERP1,RHOB,MYO1F,MRPL27,DBI,CAPN7,OGT,PPA2,MLYCD,TAF6,MZT2B,ZMAT3,SLC25A39,HIGD2A |
| 1.581e-02 | -4.15 | BIOCARTA_RAS_PATHWAY | MSigDB lists | BIOCARTA_RAS_PATHWAY | 23 | 8 | 17377 | 2626 |
BCL2L1,RHOA,CDC42,ELK1,HRAS,RAF1,RAC1,MAPK3 |
| 1.581e-02 | -4.15 | GO_OXIDOREDUCTASE_ACTIVITY_ACTING_ON_A_HEME_GROUP_OF_DONORS | MSigDB lists | GO_OXIDOREDUCTASE_ACTIVITY_ACTING_ON_A_HEME_GROUP_OF_DONORS | 23 | 8 | 17377 | 2626 |
COX5B,COX15,COX7A2L,COX8A,COX5A,COX4I1,NDUFA4,CYB5A |
| 1.581e-02 | -4.15 | GCM_CASP2 | MSigDB lists | GCM_CASP2 | 23 | 8 | 17377 | 2626 |
USP39,DDX47,THRAP3,BAZ2A,SPPL2B,CCAR1,S100PBP,CS |
| 1.581e-02 | -4.15 | BIOCARTA_CCR3_PATHWAY | MSigDB lists | BIOCARTA_CCR3_PATHWAY | 23 | 8 | 17377 | 2626 |
GNAS,RHOA,MAPK1,LIMK1,HRAS,RAF1,CFL1,MAPK3 |
| 1.581e-02 | -4.15 | GO_MULTI_ORGANISM_MEMBRANE_BUDDING | MSigDB lists | GO_MULTI_ORGANISM_MEMBRANE_BUDDING | 23 | 8 | 17377 | 2626 |
CHMP2A,PDCD6IP,CHMP4A,CHMP4B,VPS4A,CHMP2B,LRSAM1,CHMP7 |
| 1.581e-02 | -4.15 | BIOCARTA_IGF1R_PATHWAY | MSigDB lists | BIOCARTA_IGF1R_PATHWAY | 23 | 8 | 17377 | 2626 |
SHC1,RPS6KA1,RAF1,PRKAR1B,YWHAH,MAPK1,HRAS,MAPK3 |
| 1.581e-02 | -4.15 | KEGG_MISMATCH_REPAIR | MSigDB lists | KEGG_MISMATCH_REPAIR | 23 | 8 | 17377 | 2626 |
RPA2,PCNA,RFC3,PMS2,MSH2,RFC2,MSH6,RPA1 |
| 1.581e-02 | -4.15 | GO_VIRAL_BUDDING | MSigDB lists | GO_VIRAL_BUDDING | 23 | 8 | 17377 | 2626 |
CHMP2A,CHMP4A,PDCD6IP,CHMP4B,VPS4A,CHMP2B,LRSAM1,CHMP7 |
| 1.581e-02 | -4.15 | BARIS_THYROID_CANCER_UP | MSigDB lists | BARIS_THYROID_CANCER_UP | 23 | 8 | 17377 | 2626 |
RPN1,NRF1,EIF2S2,SNRNP200,ATP6V1D,CRNKL1,CYCS,CYC1 |
| 1.581e-02 | -4.15 | HOLLEMAN_ASPARAGINASE_RESISTANCE_B_ALL_UP | MSigDB lists | HOLLEMAN_ASPARAGINASE_RESISTANCE_B_ALL_UP | 23 | 8 | 17377 | 2626 |
EIF3K,EIF3L,EIF3D,RPL6,CCDC69,FBL,LPCAT1,RPL11 |
| 1.581e-02 | -4.15 | GO_NUCLEOTIDE_EXCISION_REPAIR_DNA_DAMAGE_RECOGNITION | MSigDB lists | GO_NUCLEOTIDE_EXCISION_REPAIR_DNA_DAMAGE_RECOGNITION | 23 | 8 | 17377 | 2626 |
COPS8,COPS7B,COPS6,RBX1,RPS27A,DDB1,XPA,RAD23B |
| 1.581e-02 | -4.15 | GO_MULTI_ORGANISM_ORGANELLE_ORGANIZATION | MSigDB lists | GO_MULTI_ORGANISM_ORGANELLE_ORGANIZATION | 23 | 8 | 17377 | 2626 |
CHMP2A,CHMP4A,PDCD6IP,CHMP4B,VPS4A,CHMP2B,LRSAM1,CHMP7 |
| 1.581e-02 | -4.15 | GO_CYSTEINE_TYPE_ENDOPEPTIDASE_INHIBITOR_ACTIVITY_INVOLVED_IN_APOPTOTIC_PROCESS | MSigDB lists | GO_CYSTEINE_TYPE_ENDOPEPTIDASE_INHIBITOR_ACTIVITY_INVOLVED_IN_APOPTOTIC_PROCESS | 23 | 8 | 17377 | 2626 |
TNFAIP8,BIRC3,PRDX3,BIRC5,RPS6KA1,PRDX5,XIAP,BIRC2 |
| 1.581e-02 | -4.15 | BIOCARTA_CTCF_PATHWAY | MSigDB lists | BIOCARTA_CTCF_PATHWAY | 23 | 8 | 17377 | 2626 |
TGFB1,PPP2CA,CDKN1B,MDM2,SMAD1,PTEN,SMAD4,CDKN2A |
| 1.584e-02 | -4.15 | GSE1 (Gse1 coiled-coil protein) | protein interactions | 23199 | 43 | 13 | 17029 | 2761 |
EXOSC6,GOLGA2,TCF3,FUS,CEP63,FAM136A,RCOR3,HMG20A,EYA2,HDAC2,MAPK3,CDC5L,SRPK2 |
| 1.584e-02 | -4.15 | ATF1 (activating transcription factor 1) | protein interactions | 466 | 43 | 13 | 17029 | 2761 |
TFAP4,MAPKAPK3,GABPA,NFIL3,MIA2,CSNK2A1,BRCA1,EDF1,CREB1,ATF2,PRKACA,CAMK2G,CREM |
| 1.584e-02 | -4.15 | WDHD1 (WD repeat and HMG-box DNA binding protein 1) | protein interactions | 11169 | 43 | 13 | 17029 | 2761 |
RPA2,SNRNP200,KAT2A,HNRNPR,MAP4,NCOA1,YY1,COA7,NCOA2,POLR2A,GINS4,RPA1,ZMYM3 |
| 1.584e-02 | -4.15 | PHLPP1 (PH domain and leucine rich repeat protein phosphatase 1) | protein interactions | 23239 | 43 | 13 | 17029 | 2761 |
RPAP3,SNX27,BRAP,FKBP5,DMWD,PPP5C,CSNK1A1,RBM15,MCMBP,MARK2,WDR48,FANCI,NUDC |
| 1.584e-02 | -4.15 | HERC5 (HECT and RLD domain containing E3 ubiquitin protein ligase 5) | protein interactions | 51191 | 43 | 13 | 17029 | 2761 |
RPS2,CCNA2,FOXM1,DGCR8,STK38,IRF3,CCNB1,BECN1,CCDC59,ZC3H3,SMAD4,GPATCH4,ISG15 |
| 1.584e-02 | -4.15 | SULT1A1 (sulfotransferase family 1A member 1) | protein interactions | 6817 | 43 | 13 | 17029 | 2761 |
THADA,UBXN1,PPM1G,ZRANB2,UBE4B,PTGES3,ATP6V1B2,AHCYL1,COMMD4,STAM,SSSCA1,USP34,SRXN1 |
| 1.584e-02 | -4.15 | PPP2R5C (protein phosphatase 2 regulatory subunit B'gamma) | protein interactions | 5527 | 43 | 13 | 17029 | 2761 |
CNOT9,PPP2CA,PPP2R5A,UGP2,LSM6,AXIN1,JMJD6,BRCA1,CHEK2,API5,MAPK1,APP,FAF1 |
| 1.584e-02 | -4.15 | MCFD2 (multiple coagulation factor deficiency 2) | protein interactions | 90411 | 43 | 13 | 17029 | 2761 |
LARS,PSMD3,COPE,DCTN2,LAGE3,CAPZA1,POLR2D,RUVBL2,LMAN1,IGBP1,APP,PFKP,PSMC4 |
| 1.584e-02 | -4.15 | PPIG (peptidylprolyl isomerase G) | protein interactions | 9360 | 43 | 13 | 17029 | 2761 |
SARNP,ZCCHC10,CLK3,ZMYND11,PPCDC,CUL3,JMJD6,NUF2,LUC7L,PCBP1,NKAPD1,PIP4K2A,POLR2A |
| 1.584e-02 | -4.15 | MAPK11 (mitogen-activated protein kinase 11) | protein interactions | 5600 | 43 | 13 | 17029 | 2761 |
C9orf78,MKNK1,MAPKAPK3,PPM1G,PTPN7,PML,BCL2,ELK1,ATF2,MAPK14,APP,HTRA2,EEF2K |
| 1.584e-02 | -4.15 | CDC40 (cell division cycle 40) | protein interactions | 51362 | 43 | 13 | 17029 | 2761 |
SMAD2,EIF4A3,XAB2,SUZ12,EFTUD2,CRNKL1,DHX8,SNRPG,ISY1-RAB43,NKAPD1,SMURF1,LUC7L2,PRPF19 |
| 1.584e-02 | -4.15 | Glycosaminoglycan biosynthesis - keratan sulfate | KEGG pathways | hsa00533 | 14 | 6 | 7161 | 1149 |
B4GALT1,ST3GAL2,B4GALT4,B4GALT3,FUT8,B4GALT2 |
| 1.584e-02 | -4.15 | APC/C complex | KEGG pathways | hsa_M00389 | 14 | 6 | 7161 | 1149 |
ANAPC2,ANAPC7,CDC16,CDC23,CDC27,ANAPC4 |
| 1.584e-02 | -4.15 | APC/C complex | KEGG pathways | M00389 | 14 | 6 | 7161 | 1149 |
ANAPC2,ANAPC7,CDC16,CDC23,CDC27,ANAPC4 |
| 1.584e-02 | -4.15 | Glycosaminoglycan biosynthesis - keratan sulfate | KEGG pathways | ko00533 | 14 | 6 | 7161 | 1149 |
B4GALT1,ST3GAL2,B4GALT3,B4GALT4,FUT8,B4GALT2 |
| 1.585e-02 | -4.14 | SWI/SNF complex | cellular component | GO:0016514 | 15 | 6 | 18223 | 2701 |
SMARCA4,RB1,ARID1A,SMARCE1,ARID1B,SMARCD1 |
| 1.585e-02 | -4.14 | SAGA complex | cellular component | GO:0000124 | 15 | 6 | 18223 | 2701 |
SUPT20H,TAF6L,USP22,TAF12,TAF6,SGF29 |
| 1.592e-02 | -4.14 | GSE18281_SUBCAPSULAR_VS_CENTRAL_CORTICAL_REGION_OF_THYMUS_UP | MSigDB lists | GSE18281_SUBCAPSULAR_VS_CENTRAL_CORTICAL_REGION_OF_THYMUS_UP | 167 | 36 | 17377 | 2626 |
PTTG1,EBNA1BP2,C2orf49,STMN1,GNB2,COPB2,SSR1,SPPL2A,CAPN2,NOL11,ITGB8,CCDC50,CENPJ,GRSF1,PPA1,ATP13A1,SUGP2,ADSL,EXOSC9,EAF2,PITPNB,DNAJA1,SOX4,MRPS14,USP36,IWS1,KIF2A,UTP20,HGS,TRIM26,SLC38A7,DTX4,PML,NUP62,RGL1,EHD4 |
| 1.592e-02 | -4.14 | GSE6259_33D1_POS_VS_DEC205_POS_SPLENIC_DC_UP | MSigDB lists | GSE6259_33D1_POS_VS_DEC205_POS_SPLENIC_DC_UP | 167 | 36 | 17377 | 2626 |
HIVEP3,HECA,ATXN3,PNISR,ATG2B,CRLF3,STAM,CCDC28A,JMY,WDR48,SLC25A36,TERF2IP,RFWD3,AHCTF1,METTL14,ARHGEF2,BCL2,MDFIC,NCOA2,FDFT1,SRPK2,NIPAL3,MAPRE2,TRIM8,HELB,FRAT2,USP10,PNPLA8,TANC1,BSDC1,WNT5B,CCDC69,ST3GAL2,PDCD4,RHEBL1,ZSWIM6 |
| 1.594e-02 | -4.14 | positive regulation of cellular protein metabolic process | biological process | GO:0032270 | 1542 | 264 | 17256 | 2622 |
TXN,MAP3K7CL,XIAP,YTHDF3,CCNL2,CCNB1,UBE2I,PPP1R16B,PARK7,FBXO22,CDK5,CALM2,FIZ1,FNIP2,CDC25B,DNMT1,SENP1,MLST8,BAK1,PLK3,AKT2,MRNIP,TOPORS,DCUN1D5,MAP3K4,BRMS1,RPS27A,AXIN1,OGT,ARRB2,HDAC2,SVIP,HSPH1,CLSPN,PHF23,GADD45G,PRKAA1,DHX9,CYCS,EIF2AK4,NOTCH2,PSEN1,METTL3,WDR48,CFLAR,DDRGK1,TFAP4,FKBP1A,DAPK1,MYDGF,GNAI2,PABPC1,NSUN4,SOCS5,EIF5A,MAPKAPK3,RB1CC1,ADRB2,PTTG1IP,FXR1,CYFIP2,MAP2K2,FAS,XRCC5,DERL1,HSPBP1,FNTA,GOLGA2,CSK,MAP3K5,RNF14,RNF139,ALS2,KARS,ATXN3,RAF1,EIF3D,RAC1,MAGED1,TPX2,MYH9,CREBL2,DAZAP2,PRKACA,APP,ANKIB1,TERF2IP,CRKL,SHC1,RALB,MTA1,ADCY9,MRPS27,CDKN1B,RNF19A,MAVS,CLN6,ADCY7,ANKLE2,PSRC1,CDC123,KAT7,TAOK1,MAP4K4,CIRBP,CUL3,POLR2D,WBP2,CDCA2,RAB1A,SERP1,PPP2CA,PPP2R5A,HIPK2,RPLP1,TICAM1,TRIM32,LRP8,CSNK1D,USP13,RPS2,ZFP91,MECP2,HABP4,FLOT1,MAD2L2,CCNK,PDCD10,PTEN,PTPN11,AXIN2,MAP3K14,PDPK1,KAT2A,LONRF3,TNFAIP3,JTB,MARK2,PICALM,FADD,KEAP1,PML,PSAP,CD81,CCNC,KMT2E,PPP1R15B,FAM129A,NENF,SIRT2,UBQLN2,S1PR2,MAPK14,BIRC2,FANCI,PRNP,RAP1A,EIF4A3,IL6ST,COPS8,PLK1,NCK1,RBX1,EZR,UBE2V1,CDC6,BRCA1,SOX4,PAF1,SOCS4,ADAM9,CAB39,STK11,DVL1,CLU,CHEK2,PSMC1,PPP1R12A,GORASP1,PHB2,LAMTOR3,CIB1,NKD2,RHBDD1,APOPT1,CTR9,RBM3,MDFIC,BCL2,ATP5IF1,GBA,RTF1,MAP4K3,KRAS,PSMC4,NSMF,RUVBL2,EHD4,RNF114,IFI27L1,TRAF7,SUMO2,DUSP22,LYN,BCAP31,PAIP1,USP5,RAD23A,MDM2,KIF14,PIN1,AKAP8,PDCD2,CHTOP,F2R,ABI1,DVL2,HTRA2,CHP1,TIMP2,POLR2G,BIRC3,EDEM2,TOLLIP,PEF1,RPS9,TAB2,TIMM17A,ARNTL,GADD45B,PLGRKT,MAPK1,SMURF1,SMAD4,MIF,DAP,DCUN1D4,CSNK1A1,FBXO5,FASTKD3,FGFR3,TANK,BRD7,ARHGEF2,ATG13,STAT3,TGFB1,TELO2,COA3,RHOA,ADAM17,PRKAR1B,SYMPK,HSPA1B,MAPK3,CNOT9,NEK1,PDCD6,TWSG1,OSBPL8,PKD2,UBE2C,HRAS,IFI16 |
| 1.597e-02 | -4.14 | PLEKHA8 (pleckstrin homology domain containing A8) | protein interactions | 84725 | 7 | 4 | 17029 | 2761 |
CDKN2AIPNL,ARF1,FANCI,MASTL |
| 1.597e-02 | -4.14 | Rbx1 (ring-box 1) | protein interactions | 56438 | 7 | 4 | 17029 | 2761 |
UBE2D3,CUL1,VHL,CUL3 |
| 1.597e-02 | -4.14 | Phospho1 (phosphatase, orphan 1) | protein interactions | 237928 | 7 | 4 | 17029 | 2761 |
SLC25A19,SLC4A2,MDM2,CHTF18 |
| 1.597e-02 | -4.14 | PKIB (cAMP-dependent protein kinase inhibitor beta) | protein interactions | 5570 | 7 | 4 | 17029 | 2761 |
PIN1,DYNLL1,E2F1,E2F3 |
| 1.597e-02 | -4.14 | CFAP58 (cilia and flagella associated protein 58) | protein interactions | 159686 | 7 | 4 | 17029 | 2761 |
POT1,APP,TERF1,CAND1 |
| 1.597e-02 | -4.14 | RPL41 (ribosomal protein L41) | protein interactions | 6171 | 7 | 4 | 17029 | 2761 |
MAPK14,APP,SRPK2,PRNP |
| 1.597e-02 | -4.14 | PEG3 (paternally expressed 3) | protein interactions | 5178 | 7 | 4 | 17029 | 2761 |
USP7,BRCA1,SIAH1,SIAH2 |
| 1.597e-02 | -4.14 | NHEJ1 (non-homologous end joining factor 1) | protein interactions | 79840 | 7 | 4 | 17029 | 2761 |
KRAS,NAA20,IGBP1,XRCC4 |
| 1.597e-02 | -4.14 | CCDC83 (coiled-coil domain containing 83) | protein interactions | 220047 | 7 | 4 | 17029 | 2761 |
KLC1,CHMP2A,ASPM,TTC33 |
| 1.597e-02 | -4.14 | Pank4 (pantothenate kinase 4) | protein interactions | 269614 | 7 | 4 | 17029 | 2761 |
GCC1,LDHB,MYBL2,LDHA |
| 1.597e-02 | -4.14 | INTS6L (integrator complex subunit 6 like) | protein interactions | 203522 | 7 | 4 | 17029 | 2761 |
CEP63,MAPK14,INTS1,INTS13 |
| 1.597e-02 | -4.14 | MARCH10 (membrane associated ring-CH-type finger 10) | protein interactions | 162333 | 7 | 4 | 17029 | 2761 |
ANLN,WDYHV1,APP,SRPK2 |
| 1.597e-02 | -4.14 | Fign (fidgetin) | protein interactions | 60344 | 7 | 4 | 17029 | 2761 |
MAP3K4,NLN,ORC3,NUP54 |
| 1.597e-02 | -4.14 | Notch1 (notch 1) | protein interactions | 18128 | 7 | 4 | 17029 | 2761 |
RBPJ,KAT2A,NUMB,XIAP |
| 1.597e-02 | -4.14 | Iffo1 (intermediate filament family orphan 1) | protein interactions | 320678 | 7 | 4 | 17029 | 2761 |
TAGLN2,RBM25,TXNL4A,MIER1 |
| 1.597e-02 | -4.14 | E2F8 (E2F transcription factor 8) | protein interactions | 79733 | 7 | 4 | 17029 | 2761 |
LZTR1,EWSR1,APP,TTC33 |
| 1.597e-02 | -4.14 | PGM2L1 (phosphoglucomutase 2 like 1) | protein interactions | 283209 | 7 | 4 | 17029 | 2761 |
KIF22,SKA3,PITPNB,OAZ1 |
| 1.597e-02 | -4.14 | NNMT (nicotinamide N-methyltransferase) | protein interactions | 4837 | 7 | 4 | 17029 | 2761 |
ATF6,APP,CDC73,GLOD4 |
| 1.597e-02 | -4.14 | FRZB (frizzled related protein) | protein interactions | 2487 | 7 | 4 | 17029 | 2761 |
POLA2,SMAD1,RBX1,PNO1 |
| 1.597e-02 | -4.14 | KSR2 (kinase suppressor of ras 2) | protein interactions | 283455 | 7 | 4 | 17029 | 2761 |
COPS6,MAPK1,RAF1,MAPK3 |
| 1.597e-02 | -4.14 | KLHL5 (kelch like family member 5) | protein interactions | 51088 | 7 | 4 | 17029 | 2761 |
TK1,FUS,MAP1LC3B,CUL3 |
| 1.597e-02 | -4.14 | PRPS1L1 (phosphoribosyl pyrophosphate synthetase 1-like 1) | protein interactions | 221823 | 7 | 4 | 17029 | 2761 |
PTPDC1,TERF1,TERF2,CAND1 |
| 1.597e-02 | -4.14 | HMGN4 (high mobility group nucleosomal binding domain 4) | protein interactions | 10473 | 7 | 4 | 17029 | 2761 |
TERF2IP,EWSR1,TERF1,TERF2 |
| 1.597e-02 | -4.14 | CSPG5 (chondroitin sulfate proteoglycan 5) | protein interactions | 10675 | 7 | 4 | 17029 | 2761 |
PTPN2,MLX,GOPC,TMX1 |
| 1.597e-02 | -4.14 | Uhmk1 (U2AF homology motif (UHM) kinase 1) | protein interactions | 16589 | 7 | 4 | 17029 | 2761 |
SMAD2,STMN1,SMURF1,SMAD4 |
| 1.597e-02 | -4.14 | RIBIN (rRNA promoter binding protein) | protein interactions | 125168 | 7 | 4 | 17029 | 2761 |
UBTF,ACTB,RRN3,POLR1B |
| 1.597e-02 | -4.14 | PILRB (paired immunoglobin-like type 2 receptor beta) | protein interactions | 29990 | 7 | 4 | 17029 | 2761 |
BRCA1,LYN,PTPN11,ABHD16A |
| 1.597e-02 | -4.14 | GJA5 (gap junction protein alpha 5) | protein interactions | 2702 | 7 | 4 | 17029 | 2761 |
PSMD2,UBQLN4,PRKACA,RIMS3 |
| 1.597e-02 | -4.14 | RS1 (involved in gene regulation) | protein interactions | 2703392 | 7 | 4 | 17029 | 2761 |
SP100,SUMO2,PML,PIAS2 |
| 1.597e-02 | -4.14 | TK2 (thymidine kinase 2, mitochondrial) | protein interactions | 7084 | 7 | 4 | 17029 | 2761 |
GSTK1,KRAS,MRPL9,RBM4 |
| 1.597e-02 | -4.14 | PMP2 (peripheral myelin protein 2) | protein interactions | 5375 | 7 | 4 | 17029 | 2761 |
AKR1B1,TAGLN2,HINT1,TKT |
| 1.597e-02 | -4.14 | NYAP1 (neuronal tyrosine phosphorylated phosphoinositide-3-kinase adaptor 1) | protein interactions | 222950 | 7 | 4 | 17029 | 2761 |
CYFIP1,NCKAP1,CYFIP2,CUL3 |
| 1.597e-02 | -4.14 | EIF5AL1 (eukaryotic translation initiation factor 5A-like 1) | protein interactions | 143244 | 7 | 4 | 17029 | 2761 |
EZR,PPIB,TAGLN2,EWSR1 |
| 1.597e-02 | -4.14 | ATPase activity, coupled to transmembrane movement of substances | molecular function | GO:0042626 | 116 | 27 | 17224 | 2647 |
ATP13A1,ABCA3,ABCC10,ATP2C1,TAP1,ATP6V0A1,ABCB10,ATP5F1B,ATP6V1B2,ATP6V0B,ATP6V1D,ATP1A1,ATP2A2,ATP5MC3,ATP13A3,ATP6V0A2,ABCD1,ATP6V0C,TAP2,ATP5F1A,ATP6V1C1,ATP6V0D1,ABCA1,ATP6V0E1,ABCC1,ABCC5,ATP6V1G1 |
| 1.597e-02 | -4.14 | RAB GEFs exchange GTP for GDP on RABs | REACTOME pathways | R-HSA-8876198 | 89 | 23 | 10287 | 1696 |
RAB14,TRAPPC13,ANKRD27,TRAPPC9,AKT2,DENND4C,DENND1B,RAB7A,CCZ1,MON1B,RAB6A,RAB3IP,RAB1A,RAB5B,RIC1,RAB21,RAB8A,RAB18,RINL,RAB35,CCZ1B,RAB3IL1,ALS2 |
| 1.599e-02 | -4.14 | GSE29617_DAY3_VS_DAY7_TIV_FLU_VACCINE_PBMC_2008_DN | MSigDB lists | GSE29617_DAY3_VS_DAY7_TIV_FLU_VACCINE_PBMC_2008_DN | 156 | 34 | 17377 | 2626 |
MBD1,PPIB,FGFR1OP,LIME1,EWSR1,RPLP2,HMGXB3,TCF3,MAGED1,PTTG1,ARGLU1,CCNL2,METTL3,QSOX2,GTPBP3,SLC1A4,RBM34,SRSF4,ILKAP,LUC7L2,LDHB,POU2AF1,SNRNP200,ZNF500,BTAF1,AKT2,TUBGCP5,MEN1,STX16,SYMPK,OGT,CABIN1,SNRNP70,GLCCI1 |
| 1.599e-02 | -4.14 | GSE17974_IL4_AND_ANTI_IL12_VS_UNTREATED_0.5H_ACT_CD4_TCELL_UP | MSigDB lists | GSE17974_IL4_AND_ANTI_IL12_VS_UNTREATED_0.5H_ACT_CD4_TCELL_UP | 156 | 34 | 17377 | 2626 |
COX5B,MIF4GD,ZNF768,CAST,DAP,UBE2Q1,LACTB2,DAZAP2,FLAD1,PRDM4,PPCDC,EEF1D,RBM15B,SNX25,EIF3L,RBM42,TNFAIP3,POLK,ATG9A,RPL6,KCTD20,MCL1,IL12RB1,EIF3G,RPL36,PFDN5,RAD51C,ZNF777,LMBR1,FAM122A,ASNA1,SMAD1,PSMC1,TIGD2 |
| 1.599e-02 | -4.14 | GSE26928_CENTR_MEMORY_VS_CXCR5_POS_CD4_TCELL_DN | MSigDB lists | GSE26928_CENTR_MEMORY_VS_CXCR5_POS_CD4_TCELL_DN | 156 | 34 | 17377 | 2626 |
CCDC93,SNX27,PHRF1,FAM53C,YTHDC2,FLOT1,AGPAT3,LANCL1,SNN,RBM17,KLHL5,KDM2A,NT5DC1,GEMIN4,CREB1,FAM49B,BTAF1,TEX10,TLK1,GNG7,CAMSAP1,CYFIP2,ZFAND5,MAP3K4,DTWD1,ATAD2,CTBS,HAGHL,ARAP1,PRMT7,MBOAT1,TSTD2,MAPK1,GLCCI1 |
| 1.603e-02 | -4.13 | DACOSTA_UV_RESPONSE_VIA_ERCC3_XPCS_DN | MSigDB lists | DACOSTA_UV_RESPONSE_VIA_ERCC3_XPCS_DN | 81 | 20 | 17377 | 2626 |
RB1CC1,ATP2C1,SLC25A12,AGFG1,MYO9B,EIF3A,DST,NFATC3,SP100,PTEN,ADCY9,PHF14,PDS5B,AHDC1,PDLIM5,SMAD4,TERF1,MSH6,VPS13B,ABCC1 |
| 1.603e-02 | -4.13 | GO_NEGATIVE_REGULATION_OF_INTRINSIC_APOPTOTIC_SIGNALING_PATHWAY | MSigDB lists | GO_NEGATIVE_REGULATION_OF_INTRINSIC_APOPTOTIC_SIGNALING_PATHWAY | 81 | 20 | 17377 | 2626 |
MIF,PGAP2,BCL2L12,PPIF,HSPH1,IVNS1ABP,VDAC2,MCL1,SYVN1,BCL2L1,PTTG1IP,PARK7,RRN3,NOC2L,PARL,ARHGEF2,BCL2,CLU,TRIM32,HTRA2 |
| 1.603e-02 | -4.13 | TCTGGAC,MIR-198 | MSigDB lists | TCTGGAC,MIR-198 | 81 | 20 | 17377 | 2626 |
TSHZ1,PPP1R9B,NCOR2,APH1A,ABCF2,SLC2A1,MED13L,LETMD1,TOPORS,TGOLN2,ARID1A,PHF6,RAD54B,AKAP1,SAR1A,PTEN,STAT6,FUT8,TCEA1,PURA |
| 1.607e-02 | -4.13 | HALLMARK_P53_PATHWAY | MSigDB lists | HALLMARK_P53_PATHWAY | 195 | 41 | 17377 | 2626 |
PRKAB1,TAP1,MXD4,IP6K2,FOXO3,APP,MXD1,CCNK,RB1,MDM2,PCNA,CCP110,KIF13B,EI24,F2R,GM2A,ABCC5,LDHB,BAK1,TGFB1,PLK3,CDKN2AIP,TRAFD1,MAPKAPK3,BTG2,NOL8,CYFIP2,PRMT2,RHBDF2,FAS,RPL36,RAD51C,HINT1,SEC61A1,AEN,CD81,TOB1,ZMAT3,HRAS,DEF6,CDKN2A |
| 1.607e-02 | -4.13 | GSE7219_WT_VS_NIK_NFKB2_KO_LPS_AND_ANTI_CD40_STIM_DC_UP | MSigDB lists | GSE7219_WT_VS_NIK_NFKB2_KO_LPS_AND_ANTI_CD40_STIM_DC_UP | 195 | 41 | 17377 | 2626 |
SRSF6,TPX2,CDCA3,UCK1,ABCB10,STMN1,CMTM6,HDDC2,FANCL,SSBP3,DUT,FUT8,FBXO7,KIFAP3,CDC25B,STAT3,IFRD1,TK1,HMGN5,RNASEH2C,MKI67,RRM2,FBXO9,GORAB,KCNQ1,ANLN,SHCBP1,BORA,TOLLIP,HSPA4,BIRC5,C4orf46,HMGB2,ANP32E,NCOA1,PTPDC1,TFDP2,UBE2C,CCNB2,TOB1,SVIP |
| 1.607e-02 | -4.13 | GSE38304_MYC_NEG_VS_POS_GC_BCELL_UP | MSigDB lists | GSE38304_MYC_NEG_VS_POS_GC_BCELL_UP | 195 | 41 | 17377 | 2626 |
ZBTB37,KIF23,SMC6,PTP4A3,ZFYVE21,MEF2A,TOP2B,STMN1,FOXO3,TMCC3,EEF2K,CDKN2C,PPP1R3B,CTNNBL1,SIAH1,CENPJ,IL6ST,PHF14,DAPK1,TTC3,CREB1,N4BP2,SMC4,TIMP2,BIRC3,KIAA0040,PGGT1B,HSDL1,ITM2A,MAP4K3,RTF1,LRRC1,RAB3IP,ARL5B,RBM38,HSPB11,ETS2,BRWD1,CHD3,CERS6,S100PBP |
| 1.610e-02 | -4.13 | REACTOME_CROSS_PRESENTATION_OF_SOLUBLE_EXOGENOUS_ANTIGENS_ENDOSOMES | MSigDB lists | REACTOME_CROSS_PRESENTATION_OF_SOLUBLE_EXOGENOUS_ANTIGENS_ENDOSOMES | 46 | 13 | 17377 | 2626 |
PSMD2,PSMD1,PSMA6,PSMA8,PSMD8,PSMD3,PSMB7,PSMA1,PSMB9,PSMD9,PSMC1,PSMB3,PSMC4 |
| 1.610e-02 | -4.13 | PID_RHOA_REG_PATHWAY | MSigDB lists | PID_RHOA_REG_PATHWAY | 46 | 13 | 17377 | 2626 |
VAV1,RHOA,NET1,VAV2,ARHGEF1,TRIO,ARAP1,CDKN1B,ARHGEF2,ARHGDIB,ARHGEF12,MYO9B,DEF6 |
| 1.610e-02 | -4.13 | MORF_UBE2A | MSigDB lists | MORF_UBE2A | 46 | 13 | 17377 | 2626 |
PDCD10,SMAD2,ARPC5,ARF5,RAC1,MEA1,PPP1R11,RAB1A,PARN,PRPSAP1,RAB11A,MYL12B,DDB1 |
| 1.610e-02 | -4.13 | GO_PROTEIN_TARGETING_TO_MITOCHONDRION | MSigDB lists | GO_PROTEIN_TARGETING_TO_MITOCHONDRION | 46 | 13 | 17377 | 2626 |
TIMM8B,TOMM20,HSPA4,TIMM13,MTX3,TIMM23,TIMM17A,FBXO7,MTX1,TOMM40,MTX2,MFN2,TIMM50 |
| 1.610e-02 | -4.13 | OLSSON_E2F3_TARGETS_DN | MSigDB lists | OLSSON_E2F3_TARGETS_DN | 46 | 13 | 17377 | 2626 |
PLK1,PCNA,CCNA2,MAGED1,PTTG1,USP32,E2F3,TPX2,MYBL2,RRM2,HMGB2,TAF6L,UBE2C |
| 1.610e-02 | -4.13 | FLOT2 (flotillin 2) | protein interactions | 2319 | 71 | 19 | 17029 | 2761 |
COX15,RAB7A,HNRNPUL2,SLC26A6,VDAC2,FLOT1,GORASP2,TOMM40,VDAC1,MRPS14,MYEF2,APP,SSR1,CCP110,CHMP4B,MAVS,TFG,ECPAS,F2R |
| 1.610e-02 | -4.13 | VBP1 (VHL binding protein 1) | protein interactions | 7411 | 71 | 19 | 17029 | 2761 |
KARS,PPP3CA,EWSR1,VHL,POC1A,UBQLN2,GNB2,CLNS1A,PFDN5,EPRS,IARS,PFDN4,PDRG1,QARS,ANP32A,PRPF4,TTLL12,SGF29,DCAF5 |
| 1.610e-02 | -4.13 | ADSL (adenylosuccinate lyase) | protein interactions | 158 | 71 | 19 | 17029 | 2761 |
FGFR1OP,DNAJB1,CNTROB,UBQLN2,MCM2,API5,PAIP1,NPLOC4,CEP104,GART,KLHL20,ATIC,CENPJ,RAD23B,WDR4,DDA1,BTF3L4,EHD4,LDHB |
| 1.610e-02 | -4.13 | Ppp1cb (protein phosphatase 1, catalytic subunit, beta isoform) | protein interactions | 19046 | 71 | 19 | 17029 | 2761 |
PPP1R12A,LUZP1,PPP1R2,PPP1R15B,DHX9,CAPZA2,PABPC4,CD59,KIF18A,AHNAK,KIF18B,PPP1R8,MYO18A,PPP1R12C,CLTB,SMURF1,MYO5A,PARD3,SPTAN1 |
| 1.610e-02 | -4.13 | TXNIP (thioredoxin interacting protein) | protein interactions | 10628 | 71 | 19 | 17029 | 2761 |
TXNL1,SART1,TXN,PRKAA1,SLC2A1,IL12RB1,MBD3,TRIM28,HSPA1B,AHNAK,RAD18,MTA1,KBTBD7,PTPN11,CDKN1B,CRY2,KPNA2,ECD,EIF5 |
| 1.612e-02 | -4.13 | IBB | prosite domains | PS51214 | 8 | 4 | 12060 | 1670 |
KPNA2,SNUPN,KPNA4,KPNA1 |
| 1.612e-02 | -4.13 | PIPK | prosite domains | PS51455 | 8 | 4 | 12060 | 1670 |
PIKFYVE,PIP4K2A,PIP5K1C,PIP4K2C |
| 1.612e-02 | -4.13 | FCP1 | prosite domains | PS50969 | 8 | 4 | 12060 | 1670 |
CTDP1,CTDSP2,TIMM50,UBLCP1 |
| 1.612e-02 | -4.13 | CLAT_ADAPTOR_S | prosite domains | PS00989 | 8 | 4 | 12060 | 1670 |
AP1S1,AP3S1,AP3S2,AP2S1 |
| 1.612e-02 | -4.13 | BIR_REPEAT_2 | prosite domains | PS50143 | 8 | 4 | 12060 | 1670 |
BIRC3,BIRC5,BIRC2,XIAP |
| 1.612e-02 | -4.13 | CID | prosite domains | PS51391 | 8 | 4 | 12060 | 1670 |
RPRD1A,CHERP,RPRD1B,U2SURP |
| 1.612e-02 | -4.13 | BH3 | prosite domains | PS01259 | 8 | 4 | 12060 | 1670 |
BAK1,BCL2,MCL1,BCL2L1 |
| 1.612e-02 | -4.13 | BH2 | prosite domains | PS01258 | 8 | 4 | 12060 | 1670 |
BAK1,BCL2,MCL1,BCL2L1 |
| 1.612e-02 | -4.13 | BH1 | prosite domains | PS01080 | 8 | 4 | 12060 | 1670 |
BAK1,BCL2,MCL1,BCL2L1 |
| 1.615e-02 | -4.13 | soft_tissue-blood_vessel-haemangioendothelioma-epithelioid | COSMIC cancer mutations | soft_tissue-blood_vessel-haemangioendothelioma-epithelioid | 15 | 6 | 17385 | 2587 |
TSC1,KRAS,FUS,NRAS,TSC2,PTEN |
| 1.615e-02 | -4.13 | villous | COSMIC cancer mutations | villous | 15 | 6 | 17385 | 2587 |
GNAS,KRAS,STK11,NRAS,PTEN,SMAD4 |
| 1.615e-02 | -4.13 | lipoma | COSMIC cancer mutations | lipoma | 15 | 6 | 17385 | 2587 |
GNAS,RB1,FUS,EWSR1,MEN1,CDKN2A |
| 1.615e-02 | -4.13 | large_intestine-adenoma-tubulovillous | COSMIC cancer mutations | large_intestine-adenoma-tubulovillous | 15 | 6 | 17385 | 2587 |
GNAS,KRAS,STK11,NRAS,PTEN,SMAD4 |
| 1.615e-02 | -4.13 | tubulovillous | COSMIC cancer mutations | tubulovillous | 15 | 6 | 17385 | 2587 |
GNAS,KRAS,STK11,NRAS,PTEN,SMAD4 |
| 1.615e-02 | -4.13 | large_intestine-rectum-adenoma-villous | COSMIC cancer mutations | large_intestine-rectum-adenoma-villous | 15 | 6 | 17385 | 2587 |
GNAS,KRAS,STK11,NRAS,PTEN,SMAD4 |
| 1.615e-02 | -4.13 | haemangioendothelioma | COSMIC cancer mutations | haemangioendothelioma | 15 | 6 | 17385 | 2587 |
TSC1,KRAS,FUS,NRAS,TSC2,PTEN |
| 1.615e-02 | -4.13 | thymus-thymic_carcinoma | COSMIC cancer mutations | thymus-thymic_carcinoma | 15 | 6 | 17385 | 2587 |
KRAS,NRAS,MEN1,PTEN,HRAS,CDKN2A |
| 1.615e-02 | -4.13 | large_intestine-colon-adenoma-villous | COSMIC cancer mutations | large_intestine-colon-adenoma-villous | 15 | 6 | 17385 | 2587 |
GNAS,KRAS,STK11,NRAS,PTEN,SMAD4 |
| 1.615e-02 | -4.13 | large_intestine-colon-adenoma-tubulovillous | COSMIC cancer mutations | large_intestine-colon-adenoma-tubulovillous | 15 | 6 | 17385 | 2587 |
GNAS,KRAS,STK11,NRAS,PTEN,SMAD4 |
| 1.615e-02 | -4.13 | soft_tissue-fibrous_tissue_and_uncertain_origin-synovial_sarcoma-biphasic | COSMIC cancer mutations | soft_tissue-fibrous_tissue_and_uncertain_origin-synovial_sarcoma-biphasic | 15 | 6 | 17385 | 2587 |
RB1,SS18L1,EWSR1,NF1,PTEN,ETV6 |
| 1.615e-02 | -4.13 | ureter | COSMIC cancer mutations | ureter | 15 | 6 | 17385 | 2587 |
FGFR3,KRAS,NRAS,SF3B1,HRAS,CDKN2A |
| 1.615e-02 | -4.13 | large_intestine-adenoma-tubular | COSMIC cancer mutations | large_intestine-adenoma-tubular | 15 | 6 | 17385 | 2587 |
GNAS,KRAS,STK11,NRAS,PTEN,SMAD4 |
| 1.617e-02 | -4.12 | Stabilization of p53 | REACTOME pathways | R-HSA-69541 | 56 | 16 | 10287 | 1696 |
PSMD2,MDM2,PSMD1,PSMA6,PSMA8,RPS27A,PSMD8,PSMD3,PSMB7,PSMA1,CHEK2,PSMB9,PSMD9,PSMC1,PSMB3,PSMC4 |
| 1.617e-02 | -4.12 | Degradation of AXIN | REACTOME pathways | R-HSA-4641257 | 56 | 16 | 10287 | 1696 |
PSMD2,PSMD1,PSMA6,PSMA8,RPS27A,PSMD8,PSMD3,AXIN1,PSMB7,AXIN2,PSMA1,PSMB9,PSMD9,PSMC1,PSMB3,PSMC4 |
| 1.617e-02 | -4.12 | SCF-beta-TrCP mediated degradation of Emi1 | REACTOME pathways | R-HSA-174113 | 56 | 16 | 10287 | 1696 |
PSMA8,PSMB7,PSMA1,CUL1,PSMB9,PSMD9,PSMB3,PSMC4,FBXO5,PSMD2,PSMA6,PSMD1,RPS27A,PSMD3,PSMD8,PSMC1 |
| 1.618e-02 | -4.12 | GO_PROTEIN_N_TERMINUS_BINDING | MSigDB lists | GO_PROTEIN_N_TERMINUS_BINDING | 102 | 24 | 17377 | 2626 |
TGFB1,EIF5A,NCOR2,PHB2,MECP2,SMARCA4,CSNK2A1,MEN1,VPS25,BIRC2,CALM2,RPA2,TSC1,PEX5,PDCD10,ACOX1,EXOC4,CLU,RBPJ,NCOA1,GTF2H2,SMARCE1,PDLIM5,SPTAN1 |
| 1.619e-02 | -4.12 | cellular response to leukemia inhibitory factor | biological process | GO:1990830 | 91 | 22 | 17256 | 2622 |
SRM,GCLM,GNPNAT1,MYBL2,PTP4A3,BCLAF1,MYNN,SLC25A5,KDM3A,MPC1,TFRC,MAT2A,TWISTNB,BCAT2,XRCC5,UBXN2A,PDCD10,PML,SRSF3,CREB1,PFKP,ADAM23 |
| 1.619e-02 | -4.12 | response to leukemia inhibitory factor | biological process | GO:1990823 | 91 | 22 | 17256 | 2622 |
SRM,GCLM,GNPNAT1,MYBL2,PTP4A3,BCLAF1,MYNN,SLC25A5,KDM3A,MPC1,TFRC,MAT2A,TWISTNB,BCAT2,XRCC5,UBXN2A,PDCD10,PML,SRSF3,CREB1,PFKP,ADAM23 |
| 1.619e-02 | -4.12 | RNA polymerase II core promoter sequence-specific DNA binding | molecular function | GO:0000979 | 36 | 11 | 17224 | 2647 |
POU2AF1,ZFP64,H2AFZ,NLRC5,ZNF335,WBP2,STAT1,H2AFY,RUVBL2,H3F3A,KDM3A |
| 1.620e-02 | -4.12 | GO_PHOSPHOLIPID_BIOSYNTHETIC_PROCESS | MSigDB lists | GO_PHOSPHOLIPID_BIOSYNTHETIC_PROCESS | 229 | 47 | 17377 | 2626 |
PIGM,CDS2,PIGN,PIGQ,HEXB,AGPAT1,AGPAT3,CHKB,ARF1,CDIPT,PMVK,GGPS1,LCLAT1,PIP4K2A,CPNE3,PIP5K1C,CHKA,FGFR3,NUS1,PTEN,MTMR4,PIK3R2,LPIN2,SLC44A1,PTPN11,PIGG,PCYT2,PIKFYVE,LPCAT1,GPD1L,PGAP2,CPNE1,PIGT,DPM1,PGS1,PIP4K2C,MTMR6,TAZ,ABHD5,PI4K2A,MTMR3,AGPAT2,LPCAT4,MBOAT1,SAMD8,CHPT1,PTDSS1 |
| 1.631e-02 | -4.12 | cellular protein-containing complex localization | biological process | GO:0034629 | 23 | 8 | 17256 | 2622 |
EXOC3,EZR,NDC1,MZT1,MIOS,KLHL21,SEH1L,SNAPIN |
| 1.631e-02 | -4.12 | regulation of amyloid precursor protein catabolic process | biological process | GO:1902991 | 23 | 8 | 17256 | 2622 |
FKBP1A,TMED10,ROCK1,CLU,LYN,APP,PICALM,PRNP |
| 1.631e-02 | -4.12 | nucleotide-excision repair, DNA damage recognition | biological process | GO:0000715 | 23 | 8 | 17256 | 2622 |
COPS8,RBX1,RPS27A,XPA,RAD23B,COPS7B,COPS6,DDB1 |
| 1.631e-02 | -4.12 | negative regulation of antigen receptor-mediated signaling pathway | biological process | GO:0050858 | 23 | 8 | 17256 | 2622 |
PTPN2,GPS2,DUSP3,EZR,PAWR,PLCL2,DUSP22,PRNP |
| 1.631e-02 | -4.12 | negative regulation of double-strand break repair | biological process | GO:2000780 | 23 | 8 | 17256 | 2622 |
CYREN,TRIP12,KLHL15,HELB,PARPBP,OGG1,RNF169,POLQ |
| 1.633e-02 | -4.11 | BACE1 (beta-secretase 1) | protein interactions | 23621 | 30 | 10 | 17029 | 2761 |
GGA1,SELPLG,BRI3,KHSRP,KCNQ1,PSAP,GGA2,PSEN1,APP,CSNK1D |
| 1.633e-02 | -4.11 | NECAP2 (NECAP endocytosis associated 2) | protein interactions | 55707 | 30 | 10 | 17029 | 2761 |
ANKRD28,GGA1,UFC1,AP1M1,AP2B1,GGA2,AP1B1,APP,AP2S1,CARM1 |
| 1.633e-02 | -4.11 | NAP1L5 (nucleosome assembly protein 1 like 5) | protein interactions | 266812 | 30 | 10 | 17029 | 2761 |
ZBTB21,NAP1L1,RPS2,MAGEH1,TSPYL4,FAM207A,NAP1L4,PDCD2L,MARK2,LUC7L2 |
| 1.633e-02 | -4.11 | GADD45B (growth arrest and DNA damage inducible beta) | protein interactions | 4616 | 30 | 10 | 17029 | 2761 |
CNOT9,MAP3K4,PCNA,GADD45G,CNOT6,CCNB1,CNOT6L,MAP3K5,CNOT11,CNOT3 |
| 1.633e-02 | -4.11 | Zbtb48 (zinc finger and BTB domain containing 48) | protein interactions | 100090 | 30 | 10 | 17029 | 2761 |
FAM192A,DNMT3A,EIF4A3,CLK3,XIAP,NSFL1C,TAP2,BTF3,CHTOP,CCAR1 |
| 1.633e-02 | -4.11 | IL27RA (interleukin 27 receptor subunit alpha) | protein interactions | 9466 | 30 | 10 | 17029 | 2761 |
NDC1,CELSR2,JAK1,DEPDC1,B4GALT5,TMX4,STAT1,B4GALT1,GNB2,TMX1 |
| 1.633e-02 | -4.11 | DLG5 (discs large MAGUK scaffold protein 5) | protein interactions | 9231 | 30 | 10 | 17029 | 2761 |
FGFR1OP,CEP104,ODF2,CUL3,BTBD10,CD81,SASS6,ABCA1,TERF1,MARK2 |
| 1.633e-02 | -4.11 | EFHD2 (EF-hand domain family member D2) | protein interactions | 79180 | 30 | 10 | 17029 | 2761 |
CHMP4A,TSTA3,DCK,RAE1,MYO18A,PTPN11,MYH9,USP11,GLRX3,APP |
| 1.633e-02 | -4.11 | MPHOSPH9 (M-phase phosphoprotein 9) | protein interactions | 10198 | 30 | 10 | 17029 | 2761 |
CEP104,PCM1,CCDC14,CENPJ,ODF2,YWHAZ,CNTROB,CEP63,USP11,POC5 |
| 1.633e-02 | -4.11 | MAGEB2 (MAGE family member B2) | protein interactions | 4113 | 30 | 10 | 17029 | 2761 |
USP7,CYLD,RPS14,ATXN1,BRCA1,RPS26,TRIM28,RPS9,RPL23A,RPL36 |
| 1.633e-02 | -4.11 | PRIM1 (DNA primase subunit 1) | protein interactions | 5557 | 30 | 10 | 17029 | 2761 |
POLA2,RPA2,POLE,KLHL20,PRIM2,RAE1,COPS6,CCAR1,XRCC5,RPA1 |
| 1.633e-02 | -4.11 | ATXN7L3 (ataxin 7 like 3) | protein interactions | 56970 | 30 | 10 | 17029 | 2761 |
KAT2A,TAF5L,SECISBP2,TAF12,USP22,SUPT20H,SUPT7L,SGF29,APP,ATXN7L2 |
| 1.633e-02 | -4.11 | TOM1L2 (target of myb1 like 2 membrane trafficking protein) | protein interactions | 146691 | 30 | 10 | 17029 | 2761 |
WBP2,LAGE3,AHCYL1,TOLLIP,IGBP1,SMURF1,APP,S100A6,SZRD1,SRXN1 |
| 1.633e-02 | -4.11 | BIOCARTA_PDGF_PATHWAY | MSigDB lists | BIOCARTA_PDGF_PATHWAY | 32 | 10 | 17377 | 2626 |
JAK1,SHC1,STAT6,RAF1,STAT1,CSNK2A1,ELK1,STAT3,HRAS,MAPK3 |
| 1.633e-02 | -4.11 | GO_GLOBAL_GENOME_NUCLEOTIDE_EXCISION_REPAIR | MSigDB lists | GO_GLOBAL_GENOME_NUCLEOTIDE_EXCISION_REPAIR | 32 | 10 | 17377 | 2626 |
ERCC1,RBX1,RPS27A,SUMO2,CHD1L,XPA,RAD23B,UBE2I,GTF2H2,DDB1 |
| 1.633e-02 | -4.11 | GO_REGULATION_OF_DOUBLE_STRAND_BREAK_REPAIR | MSigDB lists | GO_REGULATION_OF_DOUBLE_STRAND_BREAK_REPAIR | 32 | 10 | 17377 | 2626 |
TERF2IP,RPA2,TRIP12,FOXM1,HELB,RAD51AP1,PML,OGG1,RNF169,POLQ |
| 1.633e-02 | -4.11 | ST_ERK1_ERK2_MAPK_PATHWAY | MSigDB lists | ST_ERK1_ERK2_MAPK_PATHWAY | 32 | 10 | 17377 | 2626 |
MKNK1,RAP1A,SHC1,RPS6KA1,CREB1,KLF6,MAPK1,MAP2K2,MAPK3,EEF2K |
| 1.633e-02 | -4.11 | CAFFAREL_RESPONSE_TO_THC_UP | MSigDB lists | CAFFAREL_RESPONSE_TO_THC_UP | 32 | 10 | 17377 | 2626 |
SEC31A,RPS2,FNTA,PNISR,MCCC1,CDKN1B,ZRANB2,KCMF1,YY1AP1,TFRC |
| 1.633e-02 | -4.11 | MMS_MOUSE_LYMPH_HIGH_4HRS_UP | MSigDB lists | MMS_MOUSE_LYMPH_HIGH_4HRS_UP | 32 | 10 | 17377 | 2626 |
SP3,RAB18,NQO1,DCK,PGRMC1,RRM2,CDC6,PTDSS1,MARK2,CYB5A |
| 1.633e-02 | -4.11 | MODULE_278 | MSigDB lists | MODULE_278 | 32 | 10 | 17377 | 2626 |
FBXO21,GCLM,GART,TRIP12,PRPS2,UBE2V1,UBE3C,UBE2C,UBE2M,WWP2 |
| 1.635e-02 | -4.11 | GSE27786_LIN_NEG_VS_NEUTROPHIL_DN | MSigDB lists | GSE27786_LIN_NEG_VS_NEUTROPHIL_DN | 184 | 39 | 17377 | 2626 |
PRKAB1,C9orf78,HECA,CAST,HLA-E,RAF1,TMX4,KLC1,EZH1,CCNL2,MIEN1,CMTM6,CFLAR,C14orf119,CRAT,CITED2,MORC3,DCTN1,SAP30,RPP25,TRIM8,RPRD1A,TACC1,NCK1,CIC,EMB,PGS1,AKT2,MTMR6,ANAPC2,KRAS,PLEC,ZFAND5,TRAM2,ACLY,TBPL1,DCAF11,RBPJ,ZC3HAV1 |
| 1.635e-02 | -4.11 | GSE27786_CD4_TCELL_VS_NEUTROPHIL_DN | MSigDB lists | GSE27786_CD4_TCELL_VS_NEUTROPHIL_DN | 184 | 39 | 17377 | 2626 |
PPP1R37,DYNLL1,CDK2AP2,MAP1LC3B,TMEM165,ZNF518A,ARL6IP6,MDM2,MBD2,CAPZA1,SLC35C2,FBXL19,STAT3,ASB6,PHF10,PPP1R18,TIMP2,PBXIP1,NCK1,RAB7A,AMDHD2,CCNF,STK17B,RBM38,RAD54B,EVC2,PPP2R5A,GRIPAP1,HIPK2,CTBS,H2AFX,COX8A,CBLN2,STK11,CLU,SASS6,ARHGAP23,TSTD2,TMEM131 |
| 1.635e-02 | -4.11 | GSE1460_CD4_THYMOCYTE_VS_NAIVE_CD4_TCELL_ADULT_BLOOD_DN | MSigDB lists | GSE1460_CD4_THYMOCYTE_VS_NAIVE_CD4_TCELL_ADULT_BLOOD_DN | 184 | 39 | 17377 | 2626 |
ST13,MPHOSPH8,TSC22D3,HABP4,CUTA,CIB1,NIT2,EZH1,C12orf10,GSTK1,RPL19,PIK3IP1,MRPL40,MVP,SPSB3,ATP6V1G1,DDX28,FTL,HEMK1,PBXIP1,SELPLG,RPL27A,KLF6,USP21,RPS9,EIF3G,EIF3K,AHNAK,RPL32,LY75,AEN,ACAT1,PDXK,BTF3,PPP6R2,MAP3K5,FAU,LTA4H,APOL2 |
| 1.635e-02 | -4.11 | GSE5589_LPS_AND_IL10_VS_LPS_AND_IL6_STIM_IL6_KO_MACROPHAGE_45MIN_DN | MSigDB lists | GSE5589_LPS_AND_IL10_VS_LPS_AND_IL6_STIM_IL6_KO_MACROPHAGE_45MIN_DN | 184 | 39 | 17377 | 2626 |
SLC12A7,SEPHS2,GCLM,MAPRE1,ST13,SCAMP3,GGA1,AGPAT1,TKT,GGA2,PABPC4,DAD1,PIK3R2,ATP13A3,HADHB,CS,FBXL19,ZC3H3,TMBIM1,ALDH9A1,KDELR1,GPX4,LDHB,USP34,NIPAL3,SEPT9,DENND4C,ATXN1,RIT1,ECH1,CAT,GNA12,SCARB2,PEX5,TOMM6,MYO18A,EXOC4,OAZ1,IPO4 |
| 1.635e-02 | -4.11 | GSE18281_PERIMEDULLARY_CORTICAL_REGION_VS_WHOLE_MEDULLA_THYMUS_UP | MSigDB lists | GSE18281_PERIMEDULLARY_CORTICAL_REGION_VS_WHOLE_MEDULLA_THYMUS_UP | 184 | 39 | 17377 | 2626 |
TSC2,GNPDA1,CHD1L,TMEM109,SDC2,PSEN1,BZW2,LRRC14,APLP2,GSTK1,DDX56,NFATC3,INTS1,MRPS27,GEMIN4,GPD1L,CARM1,ALDH9A1,DCTN1,CELSR2,ZNF500,MAPKAPK3,BTG2,ESYT1,MEN1,EDEM2,ERC1,ABCF1,IRF5,AKAP1,SUPT16H,UBTF,INF2,CDCA4,NEIL3,PPM1G,RPLP1,BRD9,TUBB |
| 1.635e-02 | -4.11 | GSE36476_CTRL_VS_TSST_ACT_16H_MEMORY_CD4_TCELL_OLD_UP | MSigDB lists | GSE36476_CTRL_VS_TSST_ACT_16H_MEMORY_CD4_TCELL_OLD_UP | 184 | 39 | 17377 | 2626 |
HECA,MAX,CKLF,NF1,EYA1,TSC22D3,TMX4,CENPF,CUTA,ARGLU1,DNAJB1,DAZAP2,RLF,CHD1,FAM8A1,MOAP1,DLG5,GSTK1,ADD3,DBNDD1,FUT8,JOSD1,ZNF226,PIK3IP1,PLCL2,ADCY7,MAPRE2,TNFAIP3,TSPYL4,PBXIP1,CIRBP,ITM2A,NUSAP1,CBFA2T2,NDRG3,PIAS2,ITGB1,TOB1,LONP2 |
| 1.636e-02 | -4.11 | GO_OXALOACETATE_METABOLIC_PROCESS | MSigDB lists | GO_OXALOACETATE_METABOLIC_PROCESS | 11 | 5 | 17377 | 2626 |
NIT2,MDH1,GOT2,MDH2,ACLY |
| 1.636e-02 | -4.11 | GO_NEGATIVE_REGULATION_OF_NATURAL_KILLER_CELL_MEDIATED_IMMUNITY | MSigDB lists | GO_NEGATIVE_REGULATION_OF_NATURAL_KILLER_CELL_MEDIATED_IMMUNITY | 11 | 5 | 17377 | 2626 |
HLA-B,ARRB2,HLA-E,HLA-A,TAP1 |
| 1.636e-02 | -4.11 | GO_PYRIMIDINE_CONTAINING_COMPOUND_SALVAGE | MSigDB lists | GO_PYRIMIDINE_CONTAINING_COMPOUND_SALVAGE | 11 | 5 | 17377 | 2626 |
UCK1,UPRT,TK1,DCK,UCK2 |
| 1.636e-02 | -4.11 | FRASOR_TAMOXIFEN_RESPONSE_DN | MSigDB lists | FRASOR_TAMOXIFEN_RESPONSE_DN | 11 | 5 | 17377 | 2626 |
MEGF9,NAT9,EHD4,GCSH,PDCD4 |
| 1.636e-02 | -4.11 | GO_RRNA_CONTAINING_RIBONUCLEOPROTEIN_COMPLEX_EXPORT_FROM_NUCLEUS | MSigDB lists | GO_RRNA_CONTAINING_RIBONUCLEOPROTEIN_COMPLEX_EXPORT_FROM_NUCLEUS | 11 | 5 | 17377 | 2626 |
TSC1,RPS15,RRS1,NMD3,RPSA |
| 1.636e-02 | -4.11 | REACTOME_SLBP_DEPENDENT_PROCESSING_OF_REPLICATION_DEPENDENT_HISTONE_PRE_MRNAS | MSigDB lists | REACTOME_SLBP_DEPENDENT_PROCESSING_OF_REPLICATION_DEPENDENT_HISTONE_PRE_MRNAS | 11 | 5 | 17377 | 2626 |
SLBP,SNRPG,ZNF473,SNRPD3,SNRPB |
| 1.636e-02 | -4.11 | GO_EARLY_ENDOSOME_TO_GOLGI_TRANSPORT | MSigDB lists | GO_EARLY_ENDOSOME_TO_GOLGI_TRANSPORT | 11 | 5 | 17377 | 2626 |
SNX8,RAB6A,LMAN1,SURF4,SNX2 |
| 1.636e-02 | -4.11 | GO_PEPTIDYL_LYSINE_DIMETHYLATION | MSigDB lists | GO_PEPTIDYL_LYSINE_DIMETHYLATION | 11 | 5 | 17377 | 2626 |
ASH1L,SUV39H2,KDM3A,SETD3,EHMT1 |
| 1.636e-02 | -4.11 | POS_RESPONSE_TO_HISTAMINE_DN | MSigDB lists | POS_RESPONSE_TO_HISTAMINE_DN | 11 | 5 | 17377 | 2626 |
EIF2S2,TATDN1,METTL22,DPM1,CDT1 |
| 1.636e-02 | -4.11 | GO_CELL_CYCLE_DNA_REPLICATION | MSigDB lists | GO_CELL_CYCLE_DNA_REPLICATION | 11 | 5 | 17377 | 2626 |
GINS1,SLBP,PCNA,UPF1,ZNF830 |
| 1.636e-02 | -4.11 | GO_POSITIVE_REGULATION_OF_GLUCOSE_IMPORT_IN_RESPONSE_TO_INSULIN_STIMULUS | MSigDB lists | GO_POSITIVE_REGULATION_OF_GLUCOSE_IMPORT_IN_RESPONSE_TO_INSULIN_STIMULUS | 11 | 5 | 17377 | 2626 |
RNASEL,OSBPL8,AKT2,PIK3R2,PTPN11 |
| 1.636e-02 | -4.11 | GO_MITOTIC_SISTER_CHROMATID_COHESION | MSigDB lists | GO_MITOTIC_SISTER_CHROMATID_COHESION | 11 | 5 | 17377 | 2626 |
RB1,SMC3,CDCA5,PDS5B,NAA50 |
| 1.636e-02 | -4.11 | GO_AMINO_SUGAR_BIOSYNTHETIC_PROCESS | MSigDB lists | GO_AMINO_SUGAR_BIOSYNTHETIC_PROCESS | 11 | 5 | 17377 | 2626 |
AMDHD2,GNPNAT1,NANP,UAP1,GNE |
| 1.636e-02 | -4.11 | REACTOME_PURINE_RIBONUCLEOSIDE_MONOPHOSPHATE_BIOSYNTHESIS | MSigDB lists | REACTOME_PURINE_RIBONUCLEOSIDE_MONOPHOSPHATE_BIOSYNTHESIS | 11 | 5 | 17377 | 2626 |
ADSS,ADSL,IMPDH1,GART,ATIC |
| 1.636e-02 | -4.11 | GO_PYRIMIDINE_NUCLEOSIDE_SALVAGE | MSigDB lists | GO_PYRIMIDINE_NUCLEOSIDE_SALVAGE | 11 | 5 | 17377 | 2626 |
UCK1,UPRT,TK1,DCK,UCK2 |
| 1.636e-02 | -4.11 | GO_PROTEIN_CHANNEL_ACTIVITY | MSigDB lists | GO_PROTEIN_CHANNEL_ACTIVITY | 11 | 5 | 17377 | 2626 |
MCL1,TOMM20,TOMM40,TIMM23,TIMM17A |
| 1.636e-02 | -4.11 | KALMA_E2F1_TARGETS | MSigDB lists | KALMA_E2F1_TARGETS | 11 | 5 | 17377 | 2626 |
POLA2,RPA2,CCNC,PCNA,MCM2 |
| 1.636e-02 | -4.11 | GO_TELOMERE_CAP_COMPLEX | MSigDB lists | GO_TELOMERE_CAP_COMPLEX | 11 | 5 | 17377 | 2626 |
TERF2IP,POT1,TERF1,TERF2,XRCC5 |
| 1.636e-02 | -4.11 | STEGMEIER_PRE-MITOTIC_CELL_CYCLE_REGULATORS | MSigDB lists | STEGMEIER_PRE-MITOTIC_CELL_CYCLE_REGULATORS | 11 | 5 | 17377 | 2626 |
LTN1,TRIM32,CYLD,RAD18,FBXO5 |
| 1.636e-02 | -4.11 | MODULE_560 | MSigDB lists | MODULE_560 | 11 | 5 | 17377 | 2626 |
BAZ1B,SLC27A4,GTF2H2,PDE3B,SRXN1 |
| 1.636e-02 | -4.11 | GO_RIBONUCLEOPROTEIN_COMPLEX_DISASSEMBLY | MSigDB lists | GO_RIBONUCLEOPROTEIN_COMPLEX_DISASSEMBLY | 11 | 5 | 17377 | 2626 |
KLC1,KIF5B,GFM2,EIF2D,MCTS1 |
| 1.636e-02 | -4.11 | GO_NEGATIVE_REGULATION_OF_NATURAL_KILLER_CELL_MEDIATED_CYTOTOXICITY | MSigDB lists | GO_NEGATIVE_REGULATION_OF_NATURAL_KILLER_CELL_MEDIATED_CYTOTOXICITY | 11 | 5 | 17377 | 2626 |
HLA-B,ARRB2,HLA-E,HLA-A,TAP1 |
| 1.636e-02 | -4.11 | DAZARD_UV_RESPONSE_CLUSTER_G5 | MSigDB lists | DAZARD_UV_RESPONSE_CLUSTER_G5 | 11 | 5 | 17377 | 2626 |
NUCB1,RPS2,GPI,EIF3G,H2AFX |
| 1.636e-02 | -4.11 | GO_CERAMIDE_CATABOLIC_PROCESS | MSigDB lists | GO_CERAMIDE_CATABOLIC_PROCESS | 11 | 5 | 17377 | 2626 |
GALC,GM2A,NEU1,HEXB,GBA |
| 1.636e-02 | -4.11 | ANLN (anillin actin binding protein) | protein interactions | 54443 | 146 | 34 | 17029 | 2761 |
PPP1R12A,LUZP1,ACTR3,MYH9,LYN,MYL6B,LMNA,DST,INTS7,ARPC5,CAPZA1,GTSE1,AP2B1,CLTB,MICAL3,CFL1,EEF1D,MYO5A,CAMK2G,CDC5L,SPTAN1,RHOA,SEPT9,WDR1,MRPL16,CAPZA2,PLEC,SEPT7,MEN1,PICALM,INF2,CORO1C,MYO18A,NUMB |
| 1.638e-02 | -4.11 | endoplasmic reticulum quality control compartment | cellular component | GO:0044322 | 28 | 9 | 18223 | 2701 |
RPS27A,MAN1B1,SEL1L,SYVN1,EDEM2,RNF139,RNF5,RNF103,RHBDD1 |
| 1.638e-02 | -4.11 | ESCRT complex | cellular component | GO:0036452 | 28 | 9 | 18223 | 2701 |
CHMP2A,CHMP4A,HGS,CHMP4B,VPS4A,CHMP2B,CHMP7,VPS25,STAM |
| 1.642e-02 | -4.11 | kidney-carcinoma-papillary_renal_cell_carcinoma | COSMIC cancer mutations | kidney-carcinoma-papillary_renal_cell_carcinoma | 6518 | 1019 | 17385 | 2587 |
ZBTB10,ADD1,TSC2,MRPS15,KDM4A,ABCC10,PIGQ,PPP1R16B,ANKRD23,RBM4,ZNF275,PABPC4,FBXO22,EEF2K,CDK5,USF1,NEK6,NSRP1,DNAAF2,RAD23B,SRSF4,ATP13A3,MECR,AP1M1,NUP153,FNIP2,ECD,RNF26,MGAT5,KCNAB2,MLST8,USP34,PLK3,BAK1,CCDC57,TMEM115,NRAS,EHMT1,HSDL1,MCL1,PLEKHM3,SMC2,STOML2,TRIM47,AHNAK,MID1IP1,WDR11,ZNF689,LIMK1,AXIN1,MYO18A,OGT,ATE1,RNASEL,TRIM52,SMAD1,CHPF2,ZNF75A,E2F2,LONP2,ANXA11,PDCD4,NXT2,SSRP1,HIVEP3,MRPL9,KIAA0100,PHF23,RHOC,TRIO,DHX9,CERK,TOP2B,SLC4A2,TMED3,ZNRF3,EIF2AK4,ITGB5,PARN,CDC73,LMNA,GNS,CD59,DDX56,SMC3,MCM5,MEGF8,RIMS3,EFTUD2,FBXO7,ZNF326,GEMIN4,MVP,PPP6R1,PHKG2,LUC7L2,EIF3L,AGGF1,FOXK1,RBM42,PRRC2A,RB1CC1,ZMYND11,DHX29,TYW1,TEX10,GTPBP4,MYBL2,UHRF1BP1,CBFA2T2,MATR3,ABCF1,RHOB,LRRC14B,RDH11,PTPRF,MAGED2,DTWD1,OSBPL11,TXNDC16,CCDC86,PDLIM1,DUSP3,SETD3,MDH1,TMEM159,ZNF830,RUFY3,PDLIM5,RNF139,ACSF2,MRPL3,ZNF207,EXOC3,ANKRD27,ABCA3,POC1A,UBR2,ANK3,CHD1L,TPX2,MYH9,TBC1D13,SLC35B2,PRKACA,RCOR3,GLRX3,TMEM161B,STAM,REPS1,ANKIB1,APP,KIAA1147,ABHD16A,ARL6IP6,PRKD3,CLUAP1,RBM23,FBXL6,AHCTF1,ZKSCAN1,GRSF1,TBC1D14,UBA5,SEPT11,ANAPC7,RNF19A,CLN6,GPD1L,ZC3H3,TMEM9,DCTN1,ADCY7,ENPP4,CPNE1,ERMP1,POLR2L,MAP4K4,CRNKL1,RNPS1,E2F3,PFKFB3,NUSAP1,GORAB,TANC1,MAT2A,GIGYF1,GPR137,DDX17,TMEM184C,CHCHD3,KIF2A,TAF2,PEX5,CDC16,VPS26B,HIPK2,DMWD,PITRM1,ZBTB11,TUBB,LRCH1,USP13,ZNF786,TMBIM4,SESTD1,CCM2,TRAK1,ATG2B,GMCL1,UBE4A,IP6K2,ETS1,RRP36,PNO1,SRXN1,CAPN2,FBXO3,ZBTB45,ADD3,COQ4,SUV39H2,GATC,HUWE1,NDUFB4,ZNF260,DCP1A,GTSE1,GEMIN6,UBE3B,ST8SIA2,TPCN1,HNRNPM,MFSD12,SPTAN1,NUDC,TTPAL,PDPK1,STAU1,TNFAIP3,GALC,POLK,KIAA0930,MRS2,HEBP2,MRPS10,LLPH,PDE3B,PICALM,UTP20,SH3BP5,ZNF862,ZNF180,KEAP1,ACOX1,MAPK6,CAPN7,PML,LRPPRC,LY75,SLC25A19,HMGB2,RGL1,CD81,PARP10,YWHAH,ANAPC4,SNAPIN,TMEM131,DDX47,AGRN,GPBP1L1,TRIM11,PPP1R15B,FAM129A,SNX15,MCCC1,CSNK2A1,SEC16A,RUFY1,FANCI,ZER1,KRR1,FANCL,TET3,ABL2,DLG5,NUP210,NT5DC1,INTS1,IL6ST,PIK3R2,XRCC2,NOC2L,TXLNA,FAM86C1,MYBL1,MCMBP,ASB6,CCAR1,ABCC5,VPS13B,CDC37,PLK1,METTL1,CELSR2,PBXIP1,BAZ2A,RAD51AP1,TLK1,LNX2,EZR,CKAP2L,CDC6,LRP5,UBE2V1,PBRM1,BRCA1,EAF2,ANLN,RAB5B,USP21,LSG1,RHEB,OPTN,TBC1D17,FBXO28,CHD3,NAGLU,ARRDC1,ACTB,PIEZO1,ZNF45,FAM208A,NGLY1,NUDT11,POT1,MYL12B,NUMB,ZNF564,RMND5A,SEPHS2,ZCCHC9,HJURP,CENPF,NKD2,ADCK5,CDK13,NCKAP1,DOCK11,RLF,ASXL2,RSAD1,ARID1B,LRRC14,TNS3,MLX,NUS1,CCP110,SSBP3,KIF13B,ARL6IP1,TIMELESS,AHCY,RBM3,AHDC1,MAML1,HDHD2,ABCC1,TRAPPC9,NQO2,LDB1,AMD1,CAMSAP1,UTP15,KRAS,EIF2AK1,MAP4K3,ZNF761,UBE4B,METTL22,EIF4G2,ARMC8,STYXL1,IRF5,PSMC4,GOLGA4,PCM1,GALNT2,PALB2,PRPS2,ZDHHC7,PRMT7,MYO9A,UNC13C,SUCLG1,ARID2,XAB2,ZNF416,ATP6V1B2,PCBP1,LYN,RPL11,VAV1,TMEM69,CSDE1,PDK2,ATP6V0B,ZNF473,DUS4L,BRPF3,WDR44,EFCAB11,CABLES2,TOP1MT,AHCYL1,ZNF583,POC5,SNX25,KDM3B,CLPTM1,SLC39A9,RPL29,CLCN3,BIRC3,ZNF780B,PSMA8,BTG2,PPIE,CYP20A1,SLC26A6,MTMR6,NUP155,NFATC2,MRPS14,EIF3H,SRSF1,SUGP1,DNAJC10,MRPL2,ATP1A1,IDE,DHX16,PLEKHG4B,CLK3,SCAP,ZNF700,STK38,FASTK,ZNF436,DNAJC17,NCOA1,SPRYD4,FAU,SLC22A23,SMAD4,PARD3,ZNF146,ATXN7L2,INTS2,SLC30A9,CMAS,CDC40,GOLIM4,RRP15,KLHL21,CDT1,ARID5A,CDCA8,TMX3,SMC6,SUMF1,HMGN3,CSNK1A1,RMI1,BZW2,SCYL2,DNAJB9,TFRC,HERC3,GSTK1,NDUFV1,SLC35B4,DDX31,CENPM,ORC3,CAMK2G,RNF5,RNLS,RBM15B,YTHDC1,RPAP3,CNTN5,RPRD1A,SNX2,BTAF1,METTL5,TOP3A,ARHGEF12,PNPLA8,FAM50B,HAGH,API5,BSDC1,ZFR,DDX23,CACNB1,KPNA4,SEC23IP,BIRC5,SNAP29,TFE3,NEIL3,BBX,PGRMC1,GLG1,USP20,TMEM219,PKD2,NR2F2,RPS6KC1,HIPK3,SAT2,NUP188,TXN,PDCD6IP,NDUFB6,TMEM203,ZDHHC8,TAP1,USP39,CUL1,PLXNA1,NANS,UBE2I,SLC20A1,KIFC1,ASAP2,NOL11,DBNDD1,CYB5RL,MARCH2,SLC26A2,PLCL2,CDC5L,USO1,ATG9A,AKT2,PBK,NSUN2,MKI67,DDX20,GALNT7,AURKB,FOXRED1,SLC25A5,RAB2B,DOT1L,MAP3K4,ANKRD10,RBM47,KIF18B,STT3A,RPS14,TPP2,LUC7L3,PSMD8,EIF2D,ITGB1,DHTKD1,RRS1,ZNF598,ZMAT3,NMD3,HDAC2,DDX58,PWWP2A,PPIB,RECQL,C9orf78,LIME1,CHTF18,HLA-E,GSPT2,PRKAA1,ACAP1,SLC35B1,NOTCH2,MAN2B1,ZNF79,PDXDC1,NDUFS7,CNOT3,JMY,SPAG5,YY1AP1,RTKN,RPN1,CEP104,EXOSC7,LRRC8D,DAPK1,TPST1,PCYT2,MRPL40,GNAI2,LPCAT1,ANKHD1,FAM171A1,APOL1,EEF1D,TERF2,GCC2,PRIM2,SIGMAR1,WDR1,RPS24,C1orf35,KCTD20,GORASP2,EXOSC9,ARID1A,PLEC,TOMM40,PKM,MAP2K2,SF3A2,AKAP1,PI4K2A,EPRS,SLCO4A1,ZNF777,MTHFD2,GOLGA2,NSF,QARS,DCK,ACLY,PIAS2,FAM83D,USP32,APPL2,ARAP1,VCPIP1,CABIN1,SMPD4,MAP3K5,PPP6R2,PPP6R3,RNF14,CDK2,CABLES1,NRBP1,NUDT3,CDKN2A,CYTIP,TP53RK,DNMT3A,ATXN3,TRIP10,ZBTB37,URB2,SF3B1,RAF1,RPS6KA1,UROD,KIAA0232,KLHL18,BCL2L1,SLC25A44,SDHA,CRKL,FLAD1,SHC1,MTMR4,LPIN2,ADCY9,TTC3,TP53BP2,AQR,RBM12B,ILKAP,CDK12,ATP13A1,BRD4,OAF,NARF,VDAC2,CUL3,ELP4,SLBP,EDF1,PKMYT1,AP4E1,POLG2,ERC1,TRIM28,DHX57,SUPT16H,ANKZF1,VEZF1,HINT1,JAK1,DSN1,DGCR8,SAFB,HAGHL,STAT1,SEL1L,NCLN,KLHDC4,TRIM32,XRCC4,POLQ,PRPF4B,RHEBL1,NCOR2,ANKRD13D,PKP4,NDUFS1,SLC41A1,C1orf112,BABAM1,MRI1,CBLL1,BRAP,SLC25A12,MYNN,SECISBP2,HMG20A,FOXO3,REEP5,RAB11A,HEATR5B,HLA-A,TMCC3,JAKMIP1,SLC25A36,RBM17,PTEN,ELP5,CRAT,PRC1,PTPN11,MRPL54,RPL19,COPS7B,OSTC,CITED2,PACS2,NCOA2,MSH6,PDLIM2,ZFP64,LONRF3,KAT2A,DENND4C,NEK7,WDR18,RPL8,PARP4,RABIF,ADSL,PACS1,BMS1,KCNQ1,OTUD3,LRRC1,ARSK,KLF6,GUF1,MACF1,MARK2,MYO1F,SLC38A7,TTLL4,MFAP1,STX18,DDX5,DUSP11,WDR91,WDR62,BRWD3,TAF6,ESPL1,DDB1,HIGD2A,IPO4,FAM83G,BYSL,NAT9,ZNF76,SKA3,NPHP4,COPA,HNRNPAB,UBN1,NF1,DCAF15,UQCR10,PHRF1,ALKBH5,MOGS,AGFG1,SLC29A1,KIF2C,USP48,MAPK14,CUTC,SNAPC4,RNF103,SF3B2,PCYOX1L,ZNF804A,DST,CDC42,SYNM,EIF4A3,THADA,SIVA1,METTL14,ZNHIT6,GPATCH1,AKR1B1,ZBTB22,RP2,TTC4,ARID4A,DRAM2,CARM1,SRPK2,TIMM50,FYTTD1,LARS,TRAPPC13,TDP1,TRIM8,ZCCHC10,LAP3,VHL,LRBA,SREK1,KMT2C,STK17B,ABHD5,CHAF1A,UBTF,GEMIN5,PAF1,HSPB11,BRWD1,IARS2,BAZ1B,STK11,GALNT10,CLU,CHEK2,SASS6,TSTD2,DCAF5,ATP6V0E1,CAPN1,SLC12A7,PPP1R12A,TM9SF4,PCSK7,MED13L,PM20D2,SRRT,PRPF18,NUP205,LYAR,NFATC3,MED10,ZNF335,ACAD8,UBE3C,SLC12A2,ATP6V0D1,N4BP2,CSNK1G3,ZNF189,CREG1,CIC,SUGP2,OXR1,RPL6,THNSL1,SEPT7,DAPK3,ARHGAP15,CAND1,MASTL,TSC1,NAP1L1,ODF2,EXOC4,SLC16A1,FN3KRP,KIAA1328,NUP62,C11orf1,TOB1,C7orf26,N4BP2L2,ADNP2,MBD1,WASF2,ASH1L,IMMT,MPHOSPH8,WDYHV1,HNRNPUL2,PMS2,SMARCA4,UCK1,CHKB,ORC1,TWF2,CHD1,MXD1,USP5,HNRNPA2B1,RRN3,ANKLE1,FARSA,PARL,PDIA6,F2R,ZNF770,SCYL3,CSTF1,RLIM,POU2AF1,PGGT1B,SELPLG,RNF25,ATXN1,TOR1AIP2,OGDH,CADM1,BUD13,HERPUD2,PEF1,GFER,EIF3G,PON2,TMEM41A,ZNF317,STAT6,HPS5,TULP3,GADD45B,ANP32E,TMEM101,GAS2,AKNA,MAPK1,ABCA1,PDCD2L,CBX4,KIF3B,GOLPH3L,SH2D3A,EYA1,SHPRH,SCYL1,LETMD1,PAWR,MYO9B,DCUN1D4,GFM2,PIP4K2A,MFSD10,RGS1,HDDC2,FBXO5,FERMT3,KIF5B,FASTKD3,FGFR3,GART,PPIG,ATG13,TTC17,MRPL11,FBL,ERI3,FRMD8,MYO5A,MICAL3,SLC25A1,ZDHHC18,PHF20L1,TELO2,CSNK1G2,DCAF6,ADAM17,FAM49B,PSPC1,ASPM,MIER1,ATP2C1,COG1,WDR81,ZNF407,MAPK3,LEMD2,HLA-B,PLAA,ELMO1,KBTBD7,MBD6,CENPT,ZMIZ1,IDH3B,PREPL,TERF1,ZSWIM6 |
| 1.642e-02 | -4.11 | papillary_renal_cell_carcinoma | COSMIC cancer mutations | papillary_renal_cell_carcinoma | 6518 | 1019 | 17385 | 2587 |
ZBTB10,ADD1,TSC2,MRPS15,KDM4A,ABCC10,PIGQ,PPP1R16B,ANKRD23,RBM4,ZNF275,PABPC4,FBXO22,EEF2K,CDK5,USF1,NEK6,NSRP1,DNAAF2,RAD23B,SRSF4,ATP13A3,MECR,AP1M1,NUP153,FNIP2,ECD,RNF26,MGAT5,KCNAB2,MLST8,USP34,PLK3,BAK1,CCDC57,TMEM115,NRAS,EHMT1,HSDL1,MCL1,PLEKHM3,SMC2,STOML2,TRIM47,AHNAK,MID1IP1,WDR11,ZNF689,LIMK1,AXIN1,MYO18A,OGT,ATE1,RNASEL,TRIM52,SMAD1,CHPF2,ZNF75A,E2F2,LONP2,ANXA11,PDCD4,NXT2,SSRP1,HIVEP3,MRPL9,KIAA0100,PHF23,RHOC,TRIO,DHX9,CERK,TOP2B,SLC4A2,TMED3,ZNRF3,EIF2AK4,ITGB5,PARN,CDC73,LMNA,GNS,CD59,DDX56,SMC3,MCM5,MEGF8,RIMS3,EFTUD2,FBXO7,ZNF326,GEMIN4,MVP,PPP6R1,PHKG2,LUC7L2,EIF3L,AGGF1,FOXK1,RBM42,PRRC2A,RB1CC1,ZMYND11,DHX29,TYW1,TEX10,GTPBP4,MYBL2,UHRF1BP1,CBFA2T2,MATR3,ABCF1,RHOB,LRRC14B,RDH11,PTPRF,MAGED2,DTWD1,OSBPL11,TXNDC16,CCDC86,PDLIM1,DUSP3,SETD3,MDH1,TMEM159,ZNF830,RUFY3,PDLIM5,RNF139,ACSF2,MRPL3,ZNF207,EXOC3,ANKRD27,ABCA3,POC1A,UBR2,ANK3,CHD1L,TPX2,MYH9,TBC1D13,SLC35B2,PRKACA,RCOR3,GLRX3,TMEM161B,STAM,REPS1,ANKIB1,APP,KIAA1147,ABHD16A,ARL6IP6,PRKD3,CLUAP1,RBM23,FBXL6,AHCTF1,ZKSCAN1,GRSF1,TBC1D14,UBA5,SEPT11,ANAPC7,RNF19A,CLN6,GPD1L,ZC3H3,TMEM9,DCTN1,ADCY7,ENPP4,CPNE1,ERMP1,POLR2L,MAP4K4,CRNKL1,RNPS1,E2F3,PFKFB3,NUSAP1,GORAB,TANC1,MAT2A,GIGYF1,GPR137,DDX17,TMEM184C,CHCHD3,KIF2A,TAF2,PEX5,CDC16,VPS26B,HIPK2,DMWD,PITRM1,ZBTB11,TUBB,LRCH1,USP13,ZNF786,TMBIM4,SESTD1,CCM2,TRAK1,ATG2B,GMCL1,UBE4A,IP6K2,ETS1,RRP36,PNO1,SRXN1,CAPN2,FBXO3,ZBTB45,ADD3,COQ4,SUV39H2,GATC,HUWE1,NDUFB4,ZNF260,DCP1A,GTSE1,GEMIN6,UBE3B,ST8SIA2,TPCN1,HNRNPM,MFSD12,SPTAN1,NUDC,TTPAL,PDPK1,STAU1,TNFAIP3,GALC,POLK,KIAA0930,MRS2,HEBP2,MRPS10,LLPH,PDE3B,PICALM,UTP20,SH3BP5,ZNF862,ZNF180,KEAP1,ACOX1,MAPK6,CAPN7,PML,LRPPRC,LY75,SLC25A19,HMGB2,RGL1,CD81,PARP10,YWHAH,ANAPC4,SNAPIN,TMEM131,DDX47,AGRN,GPBP1L1,TRIM11,PPP1R15B,FAM129A,SNX15,MCCC1,CSNK2A1,SEC16A,RUFY1,FANCI,ZER1,KRR1,FANCL,TET3,ABL2,DLG5,NUP210,NT5DC1,INTS1,IL6ST,PIK3R2,XRCC2,NOC2L,TXLNA,FAM86C1,MYBL1,MCMBP,ASB6,CCAR1,ABCC5,VPS13B,CDC37,PLK1,METTL1,CELSR2,PBXIP1,BAZ2A,RAD51AP1,TLK1,LNX2,EZR,CKAP2L,CDC6,LRP5,UBE2V1,PBRM1,BRCA1,EAF2,ANLN,RAB5B,USP21,LSG1,RHEB,OPTN,TBC1D17,FBXO28,CHD3,NAGLU,ARRDC1,ACTB,PIEZO1,ZNF45,FAM208A,NGLY1,NUDT11,POT1,MYL12B,NUMB,ZNF564,RMND5A,SEPHS2,ZCCHC9,HJURP,CENPF,NKD2,ADCK5,CDK13,NCKAP1,DOCK11,RLF,ASXL2,RSAD1,ARID1B,LRRC14,TNS3,MLX,NUS1,CCP110,SSBP3,KIF13B,ARL6IP1,TIMELESS,AHCY,RBM3,AHDC1,MAML1,HDHD2,ABCC1,TRAPPC9,NQO2,LDB1,AMD1,CAMSAP1,UTP15,KRAS,EIF2AK1,MAP4K3,ZNF761,UBE4B,METTL22,EIF4G2,ARMC8,STYXL1,IRF5,PSMC4,GOLGA4,PCM1,GALNT2,PALB2,PRPS2,ZDHHC7,PRMT7,MYO9A,UNC13C,SUCLG1,ARID2,XAB2,ZNF416,ATP6V1B2,PCBP1,LYN,RPL11,VAV1,TMEM69,CSDE1,PDK2,ATP6V0B,ZNF473,DUS4L,BRPF3,WDR44,EFCAB11,CABLES2,TOP1MT,AHCYL1,ZNF583,POC5,SNX25,KDM3B,CLPTM1,SLC39A9,RPL29,CLCN3,BIRC3,ZNF780B,PSMA8,BTG2,PPIE,CYP20A1,SLC26A6,MTMR6,NUP155,NFATC2,MRPS14,EIF3H,SRSF1,SUGP1,DNAJC10,MRPL2,ATP1A1,IDE,DHX16,PLEKHG4B,CLK3,SCAP,ZNF700,STK38,FASTK,ZNF436,DNAJC17,NCOA1,SPRYD4,FAU,SLC22A23,SMAD4,PARD3,ZNF146,ATXN7L2,INTS2,SLC30A9,CMAS,CDC40,GOLIM4,RRP15,KLHL21,CDT1,ARID5A,CDCA8,TMX3,SMC6,SUMF1,HMGN3,CSNK1A1,RMI1,BZW2,SCYL2,DNAJB9,TFRC,HERC3,GSTK1,NDUFV1,SLC35B4,DDX31,CENPM,ORC3,CAMK2G,RNF5,RNLS,RBM15B,YTHDC1,RPAP3,CNTN5,RPRD1A,SNX2,BTAF1,METTL5,TOP3A,ARHGEF12,PNPLA8,FAM50B,HAGH,API5,BSDC1,ZFR,DDX23,CACNB1,KPNA4,SEC23IP,BIRC5,SNAP29,TFE3,NEIL3,BBX,PGRMC1,GLG1,USP20,TMEM219,PKD2,NR2F2,RPS6KC1,HIPK3,SAT2,NUP188,TXN,PDCD6IP,NDUFB6,TMEM203,ZDHHC8,TAP1,USP39,CUL1,PLXNA1,NANS,UBE2I,SLC20A1,KIFC1,ASAP2,NOL11,DBNDD1,CYB5RL,MARCH2,SLC26A2,PLCL2,CDC5L,USO1,ATG9A,AKT2,PBK,NSUN2,MKI67,DDX20,GALNT7,AURKB,FOXRED1,SLC25A5,RAB2B,DOT1L,MAP3K4,ANKRD10,RBM47,KIF18B,STT3A,RPS14,TPP2,LUC7L3,PSMD8,EIF2D,ITGB1,DHTKD1,RRS1,ZNF598,ZMAT3,NMD3,HDAC2,DDX58,PWWP2A,PPIB,RECQL,C9orf78,LIME1,CHTF18,HLA-E,GSPT2,PRKAA1,ACAP1,SLC35B1,NOTCH2,MAN2B1,ZNF79,PDXDC1,NDUFS7,CNOT3,JMY,SPAG5,YY1AP1,RTKN,RPN1,CEP104,EXOSC7,LRRC8D,DAPK1,TPST1,PCYT2,MRPL40,GNAI2,LPCAT1,ANKHD1,FAM171A1,APOL1,EEF1D,TERF2,GCC2,PRIM2,SIGMAR1,WDR1,RPS24,C1orf35,KCTD20,GORASP2,EXOSC9,ARID1A,PLEC,TOMM40,PKM,MAP2K2,SF3A2,AKAP1,PI4K2A,EPRS,SLCO4A1,ZNF777,MTHFD2,GOLGA2,NSF,QARS,DCK,ACLY,PIAS2,FAM83D,USP32,APPL2,ARAP1,VCPIP1,CABIN1,SMPD4,MAP3K5,PPP6R2,PPP6R3,RNF14,CDK2,CABLES1,NRBP1,NUDT3,CDKN2A,CYTIP,TP53RK,DNMT3A,ATXN3,TRIP10,ZBTB37,URB2,SF3B1,RAF1,RPS6KA1,UROD,KIAA0232,KLHL18,BCL2L1,SLC25A44,SDHA,CRKL,FLAD1,SHC1,MTMR4,LPIN2,ADCY9,TTC3,TP53BP2,AQR,RBM12B,ILKAP,CDK12,ATP13A1,BRD4,OAF,NARF,VDAC2,CUL3,ELP4,SLBP,EDF1,PKMYT1,AP4E1,POLG2,ERC1,TRIM28,DHX57,SUPT16H,ANKZF1,VEZF1,HINT1,JAK1,DSN1,DGCR8,SAFB,HAGHL,STAT1,SEL1L,NCLN,KLHDC4,TRIM32,XRCC4,POLQ,PRPF4B,RHEBL1,NCOR2,ANKRD13D,PKP4,NDUFS1,SLC41A1,C1orf112,BABAM1,MRI1,CBLL1,BRAP,SLC25A12,MYNN,SECISBP2,HMG20A,FOXO3,REEP5,RAB11A,HEATR5B,HLA-A,TMCC3,JAKMIP1,SLC25A36,RBM17,PTEN,ELP5,CRAT,PRC1,PTPN11,MRPL54,RPL19,COPS7B,OSTC,CITED2,PACS2,NCOA2,MSH6,PDLIM2,ZFP64,LONRF3,KAT2A,DENND4C,NEK7,WDR18,RPL8,PARP4,RABIF,ADSL,PACS1,BMS1,KCNQ1,OTUD3,LRRC1,ARSK,KLF6,GUF1,MACF1,MARK2,MYO1F,SLC38A7,TTLL4,MFAP1,STX18,DDX5,DUSP11,WDR91,WDR62,BRWD3,TAF6,ESPL1,DDB1,HIGD2A,IPO4,FAM83G,BYSL,NAT9,ZNF76,SKA3,NPHP4,COPA,HNRNPAB,UBN1,NF1,DCAF15,UQCR10,PHRF1,ALKBH5,MOGS,AGFG1,SLC29A1,KIF2C,USP48,MAPK14,CUTC,SNAPC4,RNF103,SF3B2,PCYOX1L,ZNF804A,DST,CDC42,SYNM,EIF4A3,THADA,SIVA1,METTL14,ZNHIT6,GPATCH1,AKR1B1,ZBTB22,RP2,TTC4,ARID4A,DRAM2,CARM1,SRPK2,TIMM50,FYTTD1,LARS,TRAPPC13,TDP1,TRIM8,ZCCHC10,LAP3,VHL,LRBA,SREK1,KMT2C,STK17B,ABHD5,CHAF1A,UBTF,GEMIN5,PAF1,HSPB11,BRWD1,IARS2,BAZ1B,STK11,GALNT10,CLU,CHEK2,SASS6,TSTD2,DCAF5,ATP6V0E1,CAPN1,SLC12A7,PPP1R12A,TM9SF4,PCSK7,MED13L,PM20D2,SRRT,PRPF18,NUP205,LYAR,NFATC3,MED10,ZNF335,ACAD8,UBE3C,SLC12A2,ATP6V0D1,N4BP2,CSNK1G3,ZNF189,CREG1,CIC,SUGP2,OXR1,RPL6,THNSL1,SEPT7,DAPK3,ARHGAP15,CAND1,MASTL,TSC1,NAP1L1,ODF2,EXOC4,SLC16A1,FN3KRP,KIAA1328,NUP62,C11orf1,TOB1,C7orf26,N4BP2L2,ADNP2,MBD1,WASF2,ASH1L,IMMT,MPHOSPH8,WDYHV1,HNRNPUL2,PMS2,SMARCA4,UCK1,CHKB,ORC1,TWF2,CHD1,MXD1,USP5,HNRNPA2B1,RRN3,ANKLE1,FARSA,PARL,PDIA6,F2R,ZNF770,SCYL3,CSTF1,RLIM,POU2AF1,PGGT1B,SELPLG,RNF25,ATXN1,TOR1AIP2,OGDH,CADM1,BUD13,HERPUD2,PEF1,GFER,EIF3G,PON2,TMEM41A,ZNF317,STAT6,HPS5,TULP3,GADD45B,ANP32E,TMEM101,GAS2,AKNA,MAPK1,ABCA1,PDCD2L,CBX4,KIF3B,GOLPH3L,SH2D3A,EYA1,SHPRH,SCYL1,LETMD1,PAWR,MYO9B,DCUN1D4,GFM2,PIP4K2A,MFSD10,RGS1,HDDC2,FBXO5,FERMT3,KIF5B,FASTKD3,FGFR3,GART,PPIG,ATG13,TTC17,MRPL11,FBL,ERI3,FRMD8,MYO5A,MICAL3,SLC25A1,ZDHHC18,PHF20L1,TELO2,CSNK1G2,DCAF6,ADAM17,FAM49B,PSPC1,ASPM,MIER1,ATP2C1,COG1,WDR81,ZNF407,MAPK3,LEMD2,HLA-B,PLAA,ELMO1,KBTBD7,MBD6,CENPT,ZMIZ1,IDH3B,PREPL,TERF1,ZSWIM6 |
| 1.643e-02 | -4.11 | protein acylation | biological process | GO:0043543 | 172 | 37 | 17256 | 2622 |
ZDHHC8,MECP2,MDH2,TAF6L,WDR5,SUPT7L,MEAF6,IRF4,BRPF3,NAA50,TAF5L,KANSL2,ATF2,NAA35,ZDHHC18,KAT2A,KAT7,LDB1,ELP4,USP22,OGDH,MBD3,ZDHHC3,NMT2,MBIP,GOLGA7,TEX30,DBI,OGT,ZDHHC7,TAF12,NCOA1,BEND3,RUVBL2,NAA20,SGF29,NAA60 |
| 1.646e-02 | -4.11 | Malate-Aspartate Shuttle | SMPDB pathways | SMP00129 | 4 | 3 | 992 | 167 |
SLC25A12,GOT2,MDH2 |
| 1.648e-02 | -4.11 | Alzheimer's disease(PMID:19734902) | GWAS genes | Alzheimer's disease(PMID:19734902) | 2 | 2 | 2388 | 307 |
CLU,TOMM40 |
| 1.648e-02 | -4.11 | Ovarian cancer(PMID:20852633) | GWAS genes | Ovarian cancer(PMID:20852633) | 2 | 2 | 2388 | 307 |
ANKLE1,BABAM1 |
| 1.648e-02 | -4.11 | White matter hyperintensity burden(PMID:21681796) | GWAS genes | White matter hyperintensity burden(PMID:21681796) | 2 | 2 | 2388 | 307 |
TRIM47,TRIM65 |
| 1.648e-02 | -4.11 | Coronary artery calcification(PMID:17903303) | GWAS genes | Coronary artery calcification(PMID:17903303) | 2 | 2 | 2388 | 307 |
UTP20,NUMB |
| 1.652e-02 | -4.10 | Toll Like Receptor 3 (TLR3) Cascade | REACTOME pathways | R-HSA-168164 | 99 | 25 | 10287 | 1696 |
UBE2D3,BIRC3,MAPKAPK3,RPS6KA1,DHX9,CUL1,MEF2A,UBE2V1,IRF3,ELK1,MAPK14,APP,BIRC2,FADD,MAPK3,PPP2CA,DUSP3,RPS27A,TAB2,TANK,PTPN11,TICAM1,CREB1,ATF2,MAPK1 |
| 1.652e-02 | -4.10 | TRIF-mediated TLR3/TLR4 signaling | REACTOME pathways | R-HSA-937061 | 99 | 25 | 10287 | 1696 |
UBE2D3,BIRC3,MAPKAPK3,RPS6KA1,DHX9,CUL1,MEF2A,UBE2V1,IRF3,ELK1,MAPK14,APP,BIRC2,FADD,MAPK3,PPP2CA,DUSP3,RPS27A,TAB2,TANK,PTPN11,TICAM1,CREB1,ATF2,MAPK1 |
| 1.652e-02 | -4.10 | MyD88-independent TLR3/TLR4 cascade | REACTOME pathways | R-HSA-166166 | 99 | 25 | 10287 | 1696 |
UBE2D3,BIRC3,MAPKAPK3,RPS6KA1,DHX9,CUL1,MEF2A,UBE2V1,IRF3,ELK1,MAPK14,APP,BIRC2,FADD,MAPK3,PPP2CA,DUSP3,RPS27A,TAB2,TANK,PTPN11,TICAM1,CREB1,ATF2,MAPK1 |
| 1.652e-02 | -4.10 | LLDHDRGNASE | prints domains | PR00086 | 6 | 3 | 4652 | 473 |
UEVLD,LDHA,LDHB |
| 1.652e-02 | -4.10 | RCMTFAMILY | prints domains | PR02008 | 6 | 3 | 4652 | 473 |
NOP2,NSUN4,NSUN2 |
| 1.653e-02 | -4.10 | GO_SPHINGOLIPID_METABOLIC_PROCESS | MSigDB lists | GO_SPHINGOLIPID_METABOLIC_PROCESS | 129 | 29 | 17377 | 2626 |
CSNK1G2,PPT1,GALC,HEXB,GBA,CERK,ASAH1,SUMF1,ARSK,NEU1,CREM,PPP2CA,ALDH3B1,ITGB8,ORMDL2,CERS6,CTSA,GLTP,SAMD8,ST3GAL2,SMPD4,PSAP,SPTSSA,ST8SIA2,CLN3,CLN6,HEXA,HTRA2,GM2A |
| 1.653e-02 | -4.10 | chr8q24 | MSigDB lists | chr8q24 | 129 | 29 | 17377 | 2626 |
PHF20L1,TRAPPC9,FAM49B,TSTA3,WDYHV1,RPL8,TIGD5,PTP4A3,ADCK5,PLEC,LY6E,ZNF696,EIF3H,LRRC14,DERL1,TAF2,CYHR1,FBXL6,ATAD2,TONSL,NSMCE2,NDUFB9,CYC1,TATDN1,TOP1MT,PARP10,ZC3H3,RNF139,EEF1D |
| 1.653e-02 | -4.10 | Hurthle_cell_carcinoma | COSMIC cancer mutations | Hurthle_cell_carcinoma | 204 | 42 | 17385 | 2587 |
IER2,DNAJC5,EWSR1,MAN2B1,ARID1B,KTN1,DLG5,FGFR3,BRPF3,PTEN,PRDM4,MSH2,TFG,ZC3H3,ABCC1,PRPF19,ZNF524,NRAS,VHL,NET1,MKI67,KRAS,BRCA1,MEN1,CCDC71L,FXR1,HAGH,ERC1,PRDM11,MAP3K4,GNAS,GEMIN5,ZNF862,PCM1,CCDC6,TBL3,COPS6,UBE2C,SMAD4,HRAS,EYA2,SMARCD1 |
| 1.653e-02 | -4.10 | thyroid-carcinoma-Hurthle_cell_carcinoma | COSMIC cancer mutations | thyroid-carcinoma-Hurthle_cell_carcinoma | 204 | 42 | 17385 | 2587 |
IER2,DNAJC5,EWSR1,MAN2B1,ARID1B,KTN1,DLG5,FGFR3,BRPF3,PTEN,PRDM4,MSH2,TFG,ZC3H3,ABCC1,PRPF19,ZNF524,NRAS,VHL,NET1,MKI67,KRAS,BRCA1,MEN1,CCDC71L,FXR1,HAGH,ERC1,PRDM11,MAP3K4,GNAS,GEMIN5,ZNF862,PCM1,CCDC6,TBL3,COPS6,UBE2C,SMAD4,HRAS,EYA2,SMARCD1 |
| 1.655e-02 | -4.10 | LUI_THYROID_CANCER_CLUSTER_1 | MSigDB lists | LUI_THYROID_CANCER_CLUSTER_1 | 51 | 14 | 17377 | 2626 |
SRSF11,HHEX,PLD3,APLP2,SEPT9,GOLGA8A,BTG2,SRSF6,ADCY9,ANK3,ATP13A3,CDC25B,SOX4,MFSD10 |
| 1.655e-02 | -4.10 | TBK1.DN.48HRS_UP | MSigDB lists | TBK1.DN.48HRS_UP | 51 | 14 | 17377 | 2626 |
CALM2,MAP3K4,SDHB,MLEC,PSRC1,DUSP3,TEX10,ECD,CHEK2,UBQLN2,ZMIZ1,COPB2,CDKN2A,RBM15B |
| 1.655e-02 | -4.10 | KEGG_MTOR_SIGNALING_PATHWAY | MSigDB lists | KEGG_MTOR_SIGNALING_PATHWAY | 51 | 14 | 17377 | 2626 |
PDPK1,TSC1,ULK3,TSC2,RPS6KA1,AKT2,PIK3R2,PRKAA1,CAB39,STK11,MAPK1,RHEB,MAPK3,MLST8 |
| 1.656e-02 | -4.10 | CISD3 (CDGSH iron sulfur domain 3) | protein interactions | 284106 | 76 | 20 | 17029 | 2761 |
NDUFA5,NDUFS1,TBRG4,MRPS10,CHCHD2,MTX1,ATP5PF,ECH1,STOML2,GSTK1,IDE,NDUFA2,GRSF1,COX5A,SLC16A1,MAVS,PITRM1,SLC25A1,TIMM50,NIPSNAP1 |
| 1.656e-02 | -4.10 | FBXO7 (F-box protein 7) | protein interactions | 25793 | 76 | 20 | 17029 | 2761 |
UBE2D3,BIRC3,RBX1,MAGED1,CRNKL1,PSMB7,CUL1,DUSP22,PSMB9,SRRT,BIRC2,PSMB3,PSMA6,SEC24C,NSFL1C,FBXW2,COPS7B,COPS6,PARP10,ESPL1 |
| 1.656e-02 | -4.10 | GTF3C4 (general transcription factor IIIC subunit 4) | protein interactions | 9329 | 76 | 20 | 17029 | 2761 |
PLK1,GTF3C6,FOXM1,IVNS1ABP,ANK3,HEXB,TUFM,EZR,NFATC2,BRCA1,MCM2,METTL22,API5,RAD23A,SMC3,RBPJ,EHD4,HEXA,PPP6R1,ZC3HC1 |
| 1.656e-02 | -4.10 | ERP44 (endoplasmic reticulum protein 44) | protein interactions | 23071 | 76 | 20 | 17029 | 2761 |
TGFB1,LARS,PRIM2,SNX2,ERO1A,UBE2Q1,SUMF1,MCM2,KMT2C,CDC73,PLD3,ZNF777,PDCD10,MCM5,DAPK1,USP32,COPS7B,YWHAZ,CNN2,FUS |
| 1.656e-02 | -4.10 | USO1 (USO1 vesicle transport factor) | protein interactions | 8615 | 76 | 20 | 17029 | 2761 |
USO1,XIAP,PTP4A3,DDX20,BRCA1,DNAJA1,XPO7,RAB1A,SEC16A,PRKACA,GOSR1,MAPK3,MDM2,GOLGA2,NSF,HUWE1,GTSE1,NCOA2,CDC5L,RNF114 |
| 1.657e-02 | -4.10 | AP-type membrane coat adaptor complex | cellular component | GO:0030119 | 47 | 13 | 18223 | 2701 |
GGA1,AP3S2,AP3M2,AP1M1,AP1S1,AP2B1,AP1B1,GGA2,AP4E1,AP3S1,SYNRG,PICALM,AP2S1 |
| 1.657e-02 | -4.10 | KIM_WT1_TARGETS_12HR_DN | MSigDB lists | KIM_WT1_TARGETS_12HR_DN | 201 | 42 | 17377 | 2626 |
RHOG,RPS2,HNRNPAB,RWDD1,DBF4,CLCC1,ETS1,POLR3K,MRPL19,YY1AP1,RAP1A,FBXL6,PPIG,GRSF1,PTPN11,TRA2B,ANP32A,MOB1A,TMED2,RHOBTB3,NSDHL,POLR2D,EZR,MCL1,OGFR,ZFAND5,ARMC8,CBX3,SDHB,TIMM13,SYNCRIP,RBM25,WNT5B,CORO1C,GADD45B,FAM3C,PTPN7,AEN,RRS1,NR2F2,MRPL13,LRP8 |
| 1.659e-02 | -4.10 | CNOT2 (CCR4-NOT transcription complex subunit 2) | protein interactions | 4848 | 57 | 16 | 17029 | 2761 |
CNOT9,NCOR2,UPF1,DDX24,GPS2,GPBP1L1,GADD45B,AGO2,CNOT6,CAPZA2,CNOT6L,CNOT11,TMEM165,TOB1,CNOT3,DDB1 |
| 1.659e-02 | -4.10 | RYBP (RING1 and YY1 binding protein) | protein interactions | 23429 | 57 | 16 | 17029 | 2761 |
USP7,PCGF6,E2F3,CSNK2A1,WDR5,PCGF1,FADD,CBX3,FBRS,MDM2,E2F4,TFDP1,DDX5,TFDP2,YY1,E2F2 |
| 1.659e-02 | -4.10 | MED19 (mediator complex subunit 19) | protein interactions | 219541 | 57 | 16 | 17029 | 2761 |
CCNC,POLR2I,MED8,MED10,POLR2G,POLR2L,POLR2J,POLR2K,ELL2,DCK,MED15,POLR2D,MED13L,APP,MED22,POLR2A |
| 1.659e-02 | -4.10 | EXOC4 (exocyst complex component 4) | protein interactions | 60412 | 57 | 16 | 17029 | 2761 |
EXOC3,FGFR1OP,PCM1,RALB,MTMR4,GGA1,SNAP29,ODF2,DLGAP4,PTAR1,CEP63,CNTROB,IKBIP,BECN1,MYO5A,CDC5L |
| 1.659e-02 | -4.10 | MYH11 (myosin heavy chain 11) | protein interactions | 4629 | 57 | 16 | 17029 | 2761 |
RPA2,COX15,UBXN2A,INF2,SHC1,ARPC5,POC1A,ACTR3,ZNF746,ACTB,VDAC1,LRRC59,PARK7,EIF3A,MYO5A,RPA1 |
| 1.659e-02 | -4.10 | ZGPAT (zinc finger CCCH-type and G-patch domain containing) | protein interactions | 84619 | 57 | 16 | 17029 | 2761 |
CCDC57,MTA2,KRAS,PRPF3,PCGF1,DHX15,SPAG5,PHC2,GOLGA2,CDCA7L,UPF2,PRPF4,SNRPG,TP53BP2,DVL2,TERF2 |
| 1.659e-02 | -4.10 | NIK/NF-kappaB signaling | biological process | GO:0038061 | 86 | 21 | 17256 | 2622 |
COPS8,BIRC3,PSMA8,ZFP91,PSMB7,PSMA1,CUL1,PSMB9,PSMD9,BIRC2,PSMB3,PSMC4,PSMD2,PSMA6,PSMD1,RPS27A,PSMD8,PSMD3,MAP3K14,UBE2M,PSMC1 |
| 1.659e-02 | -4.10 | fat | COSMIC cancer mutations | fat | 120 | 27 | 17385 | 2587 |
TCF12,EWSR1,NRAS,NF1,SF3B1,GNE,TMEM109,BMS1,KRAS,MEN1,ODC1,PDXDC1,MAP3K4,GNAS,RB1,ASAP2,PTEN,ETV6,NUP107,STK11,FUS,PTPDC1,MAML1,HRAS,CDKN2A,CCAR1,FAM83G |
| 1.660e-02 | -4.10 | SMAD-like_dom_sf | interpro domains | IPR017855 | 15 | 6 | 18492 | 2768 |
IRF4,IRF3,SMAD2,SMAD1,SMAD4,IRF5 |
| 1.661e-02 | -4.10 | KEGG_GLYCEROPHOSPHOLIPID_METABOLISM | MSigDB lists | KEGG_GLYCEROPHOSPHOLIPID_METABOLISM | 71 | 18 | 17377 | 2626 |
CDS2,PGS1,AGPAT1,AGPAT3,CHKB,CDIPT,TAZ,LCLAT1,CHKA,AGPAT2,LPCAT4,MBOAT1,PCYT2,CHPT1,LPCAT1,GPD1L,PTDSS1,LYPLA2 |
| 1.665e-02 | -4.10 | cervix-carcinoma | COSMIC cancer mutations | cervix-carcinoma | 42 | 12 | 17385 | 2587 |
CDKN2C,FGFR3,RB1,NRAS,NF1,PTEN,VHL,SF3B1,STK11,KRAS,HRAS,CDKN2A |
| 1.665e-02 | -4.10 | C-type lectin receptors (CLRs) | REACTOME pathways | R-HSA-5621481 | 144 | 34 | 10287 | 1696 |
RAF1,CUL1,PPP3CB,PRKACA,PSMD9,LYN,CALM2,PSMD2,NFATC3,PSMD1,PSMA6,MAP3K14,AHCYL1,UBE2M,PDPK1,PPP3CA,NRAS,PSMA8,PSMB7,PSMA1,NFATC2,UBE2V1,KRAS,ICAM2,PSMB9,PSMB3,PSMC4,TAB2,RPS27A,PSMD3,PSMD8,PPP3R1,HRAS,PSMC1 |
| 1.671e-02 | -4.09 | FUCA1 (alpha-L-fucosidase 1) | protein interactions | 2517 | 14 | 6 | 17029 | 2761 |
SUMF1,MARK2,APP,USP21,VAV2,CUL3 |
| 1.671e-02 | -4.09 | RGL2 (ral guanine nucleotide dissociation stimulator like 2) | protein interactions | 5863 | 14 | 6 | 17029 | 2761 |
KRAS,KPNA2,NRAS,KAT7,HRAS,RAC1 |
| 1.671e-02 | -4.09 | CWC25 (CWC25 spliceosome associated protein homolog) | protein interactions | 54883 | 14 | 6 | 17029 | 2761 |
ZBTB21,MDM2,COPS6,KIF13B,DVL2,GIGYF1 |
| 1.671e-02 | -4.09 | RSF1 (remodeling and spacing factor 1) | protein interactions | 51773 | 14 | 6 | 17029 | 2761 |
CSNK2A1,ATXN3,EWSR1,COPS6,MCM2,MARK2 |
| 1.671e-02 | -4.09 | HIST3H2BB (histone cluster 3 H2B family member b) | protein interactions | 128312 | 14 | 6 | 17029 | 2761 |
USP7,BRD2,MCM2,HUWE1,MCM5,CDKN2A |
| 1.671e-02 | -4.09 | COMMD5 (COMM domain containing 5) | protein interactions | 28991 | 14 | 6 | 17029 | 2761 |
CCDC93,COMMD10,COMMD6,COMMD4,COMMD8,VPS29 |
| 1.671e-02 | -4.09 | Cry1 (cryptochrome 1 (photolyase-like)) | protein interactions | 12952 | 14 | 6 | 17029 | 2761 |
TAGLN2,FBXL3,NVL,ANK3,CSNK1D,ARNTL |
| 1.671e-02 | -4.09 | CCKBR (cholecystokinin B receptor) | protein interactions | 887 | 14 | 6 | 17029 | 2761 |
GMCL1,PRKAB1,ADRB2,THADA,PRKAA1,PTPN11 |
| 1.671e-02 | -4.09 | COA3 (cytochrome c oxidase assembly factor 3) | protein interactions | 28958 | 14 | 6 | 17029 | 2761 |
COX5A,NDUFA4,COX4I1,NDUFV1,LRPPRC,TUFM |
| 1.671e-02 | -4.09 | USP6 (ubiquitin specific peptidase 6) | protein interactions | 9098 | 14 | 6 | 17029 | 2761 |
CALM2,KRAS,CDC42,APP,RAC1,USP32 |
| 1.671e-02 | -4.09 | RFPL2 (ret finger protein like 2) | protein interactions | 10739 | 14 | 6 | 17029 | 2761 |
CBWD1,RB1,MDM2,DMWD,AHNAK,MIOS |
| 1.671e-02 | -4.09 | DCLRE1B (DNA cross-link repair 1B) | protein interactions | 64858 | 14 | 6 | 17029 | 2761 |
TERF2IP,KANSL2,PRKDC,POT1,TERF1,TERF2 |
| 1.671e-02 | -4.09 | Anapc1 (anaphase promoting complex subunit 1) | protein interactions | 17222 | 14 | 6 | 17029 | 2761 |
ANAPC2,ANAPC7,CDC16,CDC23,CDC27,ANAPC4 |
| 1.671e-02 | -4.09 | ZNF770 (zinc finger protein 770) | protein interactions | 54989 | 14 | 6 | 17029 | 2761 |
NOL12,USP20,PPAN,NIFK,MPHOSPH8,RPL8 |
| 1.671e-02 | -4.09 | MRPL33 (mitochondrial ribosomal protein L33) | protein interactions | 9553 | 14 | 6 | 17029 | 2761 |
MRPL50,MRPL9,CNTROB,SYNCRIP,MRPL42,MRPL12 |
| 1.671e-02 | -4.09 | EVI5 (ecotropic viral integration site 5) | protein interactions | 7813 | 14 | 6 | 17029 | 2761 |
PLK1,CHMP4B,AURKB,BIRC5,RAB11A,FBXO5 |
| 1.671e-02 | -4.09 | COX7A2L (cytochrome c oxidase subunit 7A2 like) | protein interactions | 9167 | 14 | 6 | 17029 | 2761 |
COX5A,NDUFA4,UQCRH,NDUFS5,TIMMDC1,NDUFS4 |
| 1.671e-02 | -4.09 | ANGPTL7 (angiopoietin like 7) | protein interactions | 10218 | 14 | 6 | 17029 | 2761 |
TFAP4,CCT2,EDEM2,GNB2,APP,KBTBD7 |
| 1.671e-02 | -4.09 | CENPI (centromere protein I) | protein interactions | 2491 | 14 | 6 | 17029 | 2761 |
NIFK,CENPM,DGCR8,RBM34,APP,CENPU |
| 1.671e-02 | -4.09 | LTBP3 (latent transforming growth factor beta binding protein 3) | protein interactions | 4054 | 14 | 6 | 17029 | 2761 |
TGFB1,DNAJC10,GORASP2,ITGB5,PIK3R2,RAC1 |
| 1.671e-02 | -4.09 | DLL1 (delta like canonical Notch ligand 1) | protein interactions | 28514 | 14 | 6 | 17029 | 2761 |
EPN1,NOTCH2,PSEN1,ADAM10,POFUT1,MFNG |
| 1.671e-02 | -4.09 | TIMM8A (translocase of inner mitochondrial membrane 8A) | protein interactions | 1678 | 14 | 6 | 17029 | 2761 |
JOSD1,XRCC3,TIMM13,TIMMDC1,STAM,CDT1 |
| 1.671e-02 | -4.09 | TMEM209 (transmembrane protein 209) | protein interactions | 84928 | 14 | 6 | 17029 | 2761 |
NUP153,UBE2I,SEH1L,IFI16,NUP107,TMEM216 |
| 1.671e-02 | -4.09 | MOK (MOK protein kinase) | protein interactions | 5891 | 14 | 6 | 17029 | 2761 |
IMPDH1,CCNB1,HUWE1,WDR18,MAPK6,NAA50 |
| 1.672e-02 | -4.09 | Other types of O-glycan biosynthesis | KEGG pathways | ko00514 | 22 | 8 | 7161 | 1149 |
GXYLT1,MFNG,OGT,B4GALT1,B4GALT3,PLOD3,POFUT1,B4GALT2 |
| 1.672e-02 | -4.09 | Other types of O-glycan biosynthesis | KEGG pathways | hsa00514 | 22 | 8 | 7161 | 1149 |
GXYLT1,MFNG,OGT,B4GALT1,B4GALT3,PLOD3,POFUT1,B4GALT2 |
| 1.673e-02 | -4.09 | GO_NEGATIVE_REGULATION_OF_EXTRINSIC_APOPTOTIC_SIGNALING_PATHWAY | MSigDB lists | GO_NEGATIVE_REGULATION_OF_EXTRINSIC_APOPTOTIC_SIGNALING_PATHWAY | 97 | 23 | 17377 | 2626 |
GCLM,TNFAIP3,RB1CC1,EYA1,ZMYND11,RAF1,RFFL,MCL1,BRCA1,BCL2L1,PARK7,LMNA,FADD,HSPA1B,FAS,CFLAR,DAPK1,SIAH2,ARHGEF2,BCL2,HMGB2,TMBIM1,ZC3HC1 |
| 1.673e-02 | -4.09 | telomeric loop disassembly | biological process | GO:0090657 | 11 | 5 | 17256 | 2622 |
XRCC3,BLM,POT1,TERF1,TERF2 |
| 1.673e-02 | -4.09 | negative regulation of necroptotic process | biological process | GO:0060546 | 11 | 5 | 17256 | 2622 |
ARHGEF2,BIRC3,BIRC2,FADD,CFLAR |
| 1.673e-02 | -4.09 | lactate metabolic process | biological process | GO:0006089 | 11 | 5 | 17256 | 2622 |
HAGH,PARK7,MRS2,LDHB,LDHA |
| 1.673e-02 | -4.09 | organelle inheritance | biological process | GO:0048308 | 11 | 5 | 17256 | 2622 |
PLK3,VCPIP1,YWHAZ,PDCD10,GOLGA2 |
| 1.673e-02 | -4.09 | peptidyl-serine dephosphorylation | biological process | GO:0070262 | 11 | 5 | 17256 | 2622 |
PPP2CA,PPP5C,NCK1,PPP2R2D,PPP1R15B |
| 1.673e-02 | -4.09 | regulation of nuclear-transcribed mRNA poly(A) tail shortening | biological process | GO:0060211 | 11 | 5 | 17256 | 2622 |
POLR2G,TOB1,BTG2,PABPC1,AGO2 |
| 1.673e-02 | -4.09 | attachment of mitotic spindle microtubules to kinetochore | biological process | GO:0051315 | 11 | 5 | 17256 | 2622 |
NUF2,KIF2C,CDT1,SEH1L,MIS12 |
| 1.673e-02 | -4.09 | positive regulation of nuclear-transcribed mRNA poly(A) tail shortening | biological process | GO:0060213 | 11 | 5 | 17256 | 2622 |
POLR2G,TOB1,BTG2,PABPC1,AGO2 |
| 1.673e-02 | -4.09 | nuclear body organization | biological process | GO:0030575 | 11 | 5 | 17256 | 2622 |
ETS1,FAM118B,HIPK2,SRPK2,PML |
| 1.673e-02 | -4.09 | inhibition of cysteine-type endopeptidase activity involved in apoptotic process | biological process | GO:1990001 | 11 | 5 | 17256 | 2622 |
BCL2L12,BIRC3,BIRC5,BIRC2,XIAP |
| 1.673e-02 | -4.09 | N-acetylneuraminate metabolic process | biological process | GO:0006054 | 11 | 5 | 17256 | 2622 |
CMAS,AMDHD2,NANP,GNPDA1,GNE |
| 1.673e-02 | -4.09 | cellular hyperosmotic response | biological process | GO:0071474 | 11 | 5 | 17256 | 2622 |
AKR1B1,ARHGEF2,RCSD1,SLC2A1,XRCC5 |
| 1.677e-02 | -4.09 | GSE45365_WT_VS_IFNAR_KO_BCELL_MCMV_INFECTION_UP | MSigDB lists | GSE45365_WT_VS_IFNAR_KO_BCELL_MCMV_INFECTION_UP | 151 | 33 | 17377 | 2626 |
CDC40,CORO7,DLGAP4,CDCA8,DHX9,KIF23,YTHDF3,CDK13,ORC1,DOCK11,SUPT7L,ZNF518A,HAUS2,APOPT1,HEATR5B,MOAP1,ANKLE1,XRCC2,LTN1,HDHD2,USP34,UBQLN4,TELO2,NLN,BCLAF1,ABHD11,BRCA1,PCM1,PLAA,ETS2,U2SURP,ZC3H7B,DDX5 |
| 1.678e-02 | -4.09 | Viral carcinogenesis | KEGG pathways | ko05203 | 201 | 44 | 7161 | 1149 |
USP7,HLA-E,RAC1,IRF3,SND1,PRKACA,LYN,HLA-A,RB1,MDM2,CCNA2,SP100,CDC42,HDAC7,IL6ST,PIK3R2,CDKN1B,CREB1,ATF2,STAT3,GTF2H2,ATP6V0D1,BAK1,NRAS,RHOA,KAT2A,KRAS,PKM,MAPK3,HLA-B,JAK1,RBL1,TBPL1,YWHAZ,RBPJ,CDK2,YWHAH,MAPK1,TRAF5,PSMC1,HRAS,DDB1,CDKN2A,HDAC2 |
| 1.678e-02 | -4.09 | Viral carcinogenesis | KEGG pathways | hsa05203 | 201 | 44 | 7161 | 1149 |
USP7,HLA-E,RAC1,IRF3,SND1,PRKACA,LYN,HLA-A,RB1,MDM2,CCNA2,SP100,CDC42,HDAC7,IL6ST,PIK3R2,CDKN1B,CREB1,ATF2,STAT3,GTF2H2,ATP6V0D1,BAK1,NRAS,RHOA,KAT2A,KRAS,PKM,MAPK3,HLA-B,JAK1,RBL1,TBPL1,YWHAZ,RBPJ,CDK2,YWHAH,MAPK1,TRAF5,PSMC1,HRAS,DDB1,CDKN2A,HDAC2 |
| 1.678e-02 | -4.09 | GO_POSITIVE_REGULATION_OF_NEURON_DEATH | MSigDB lists | GO_POSITIVE_REGULATION_OF_NEURON_DEATH | 66 | 17 | 17377 | 2626 |
NQO1,NF1,MCL1,PAWR,ELK1,FOXO3,PICALM,CDK5,CDC42,PIN1,ZNF746,TP53BP2,CLU,MAP3K5,ATF2,UBE2M,SRPK2 |
| 1.678e-02 | -4.09 | GO_MACROMOLECULE_DEACYLATION | MSigDB lists | GO_MACROMOLECULE_DEACYLATION | 66 | 17 | 17377 | 2626 |
ATXN3,BAZ2A,PPT1,MTA2,RCOR1,SIRT2,MBD3,BRMS1,CHD3,MTA1,HDAC7,RBBP4,SAP30L,HDAC2,LYPLA2,ARID4A,SAP30 |
| 1.678e-02 | -4.09 | SETLUR_PROSTATE_CANCER_TMPRSS2_ERG_FUSION_UP | MSigDB lists | SETLUR_PROSTATE_CANCER_TMPRSS2_ERG_FUSION_UP | 66 | 17 | 17377 | 2626 |
SEPT9,PRKAR1B,KLC1,ARHGDIB,XRCC5,ASAP2,TPP2,MTA1,SAFB,TFDP1,NCOA1,NDUFS5,EIF5,ALDH18A1,MAP3K5,SMARCD1,PTPRK |
| 1.678e-02 | -4.09 | JOHANSSON_GLIOMAGENESIS_BY_PDGFB_UP | MSigDB lists | JOHANSSON_GLIOMAGENESIS_BY_PDGFB_UP | 56 | 15 | 17377 | 2626 |
PLK1,FTL,PCNA,PPP1R18,PBK,DBI,MKI67,RRM2,YBX1,HMGB2,TAGLN2,MCM2,KLF6,STAT3,FRMD8 |
| 1.678e-02 | -4.09 | chr8q22 | MSigDB lists | chr8q22 | 56 | 15 | 17377 | 2626 |
KLF10,POLR2K,SDC2,YWHAZ,RNF19A,RBM12B,MYBL1,MRPL13,PTDSS1,PABPC1,FZD6,ANKRD46,PLEKHF2,RAD54B,VPS13B |
| 1.679e-02 | -4.09 | Exon junction complex (EJC) | KEGG pathways | M00430 | 18 | 7 | 7161 | 1149 |
UPF2,UPF1,NXT1,EIF4A3,RBM8A,RNPS1,NXT2 |
| 1.679e-02 | -4.09 | Exon junction complex (EJC) | KEGG pathways | hsa_M00430 | 18 | 7 | 7161 | 1149 |
UPF2,UPF1,NXT1,EIF4A3,RBM8A,RNPS1,NXT2 |
| 1.681e-02 | -4.09 | DNA methylation | biological process | GO:0006306 | 46 | 13 | 17256 | 2622 |
TET3,GNAS,HEMK1,DNMT3A,BAZ2A,KMT2E,MTA2,EHMT1,PRMT7,BEND3,KDM1B,DNMT1,TRIM28 |
| 1.681e-02 | -4.09 | pyrimidine nucleotide metabolic process | biological process | GO:0006220 | 46 | 13 | 17256 | 2622 |
ERH,DCK,DUT,UCK2,CTPS1,TBPL1,UPRT,UCK1,DCTD,OGG1,HDDC2,NEIL2,MBD4 |
| 1.681e-02 | -4.09 | androgen receptor signaling pathway | biological process | GO:0030521 | 46 | 13 | 17256 | 2622 |
RB1,RHOA,RWDD1,PIAS2,DDX5,THRAP3,NCOA1,ARID1A,DNAJA1,BRCA1,KDM3A,RNF14,DDX17 |
| 1.681e-02 | -4.09 | negative regulation of mRNA catabolic process | biological process | GO:1902373 | 46 | 13 | 17256 | 2622 |
SYNCRIP,DHX9,E2F1,AXIN2,CIRBP,SECISBP2,TARDBP,YBX1,THRAP3,MAPK14,TOB1,PABPC1,PAIP1 |
| 1.681e-02 | -4.09 | peptidyl-asparagine modification | biological process | GO:0018196 | 46 | 13 | 17256 | 2622 |
RPN1,MAGT1,DDOST,DPM1,STT3A,DAD1,FUT8,ST3GAL2,RPN2,SYVN1,OSTC,LMAN1,MCFD2 |
| 1.681e-02 | -4.09 | DNA alkylation | biological process | GO:0006305 | 46 | 13 | 17256 | 2622 |
TET3,GNAS,HEMK1,DNMT3A,BAZ2A,KMT2E,MTA2,EHMT1,PRMT7,BEND3,KDM1B,DNMT1,TRIM28 |
| 1.682e-02 | -4.09 | SKP2 (S-phase kinase associated protein 2) | protein interactions | 6502 | 167 | 38 | 17029 | 2761 |
TCF3,CDT1,CUL1,ATG2B,SIRT2,ORC1,CCNB1,PSMD9,FOXO3,CHKA,RB1,MTFR1L,CCNA2,TTC9C,FBXW2,CDKN1B,SENP1,RBX1,BTG2,VHL,PRKAR1B,MYBL2,RRM2,MEF2D,BRCA1,AURKB,PFDN5,KPNA1,WDR59,E2F1,IMPDH1,COPS6,YY1,CDK2,TOB1,SMAD4,DDB1,USP13 |
| 1.683e-02 | -4.08 | Intracellular Signalling Through Adenosine Receptor A2b and Adenosine | SMPDB pathways | SMP00321 | 38 | 12 | 992 | 167 |
GNAS,MAP3K4,PDPK1,RAP1A,CDC42,RPS6KA1,CREB1,ELK1,MAPK1,ATF2,HRAS,MAP2K2 |
| 1.683e-02 | -4.08 | Intracellular Signalling Through Adenosine Receptor A2a and Adenosine | SMPDB pathways | SMP00320 | 38 | 12 | 992 | 167 |
GNAS,MAP3K4,PDPK1,RAP1A,CDC42,RPS6KA1,CREB1,ELK1,MAPK1,ATF2,HRAS,MAP2K2 |
| 1.685e-02 | -4.08 | GCM_ERBB2IP | MSigDB lists | GCM_ERBB2IP | 61 | 16 | 17377 | 2626 |
NAPG,GOLGA7,WDR11,GORASP1,MTMR4,IMPAD1,IL6ST,MAP4K4,TOR1AIP1,CAB39,GLTP,AHCYL1,RNF14,MACF1,RAB22A,VPS13B |
| 1.689e-02 | -4.08 | AURKA Activation by TPX2 | REACTOME pathways | R-HSA-8854518 | 75 | 20 | 10287 | 1696 |
PLK1,FGFR1OP,MAPRE1,DYNLL1,DCTN2,TPX2,HAUS4,PRKACA,HAUS2,HAUS8,PCM1,CCP110,CENPJ,ODF2,SSNA1,CEP63,NDE1,TUBB,CSNK1D,DCTN1 |
| 1.689e-02 | -4.08 | Metabolism of carbohydrates | REACTOME pathways | R-HSA-71387 | 296 | 63 | 10287 | 1696 |
GALK1,NDC1,NUP188,UGP2,AGRN,GNPDA1,MANBA,B4GALT5,RAE1,MDH2,SLC2A1,HEXB,TKT,SDC2,NUP54,SLC25A12,B4GALT1,ADPGK,MAN2B1,GYG1,SLC35B2,B4GALT4,PRKACA,EXT2,NUP205,EPM2A,GNS,CALM2,NUP210,GOT2,NUP107,AKR1B1,NUP153,SLC26A2,TALDO1,PHKG2,NUP85,SEH1L,SLC25A1,ABCC5,CHP1,B3GALT6,PFKFB3,NUP155,PKM,SLC50A1,PPP2CA,SGSH,RPS27A,PRPS2,NAGLU,NUP62,MDH1,ST3GAL2,GPI,B4GALT3,HEXA,PGAM1,CHPF2,NUP58,PFKP,AAAS,B4GALT2 |
| 1.690e-02 | -4.08 | RNA polymerase binding | molecular function | GO:0070063 | 70 | 18 | 17224 | 2647 |
PPIB,BRD4,PHRF1,YTHDC2,AGO2,DHX9,ELP4,WDHD1,RTF1,BRCA1,CDC73,PAF1,RRN3,ZNF326,CTR9,TCOF1,RPRD1B,ELOF1 |
| 1.690e-02 | -4.08 | GSE39556_UNTREATED_VS_3H_POLYIC_INJ_MOUSE_NK_CELL_UP | MSigDB lists | GSE39556_UNTREATED_VS_3H_POLYIC_INJ_MOUSE_NK_CELL_UP | 190 | 40 | 17377 | 2626 |
FOXM1,RRM1,BLM,RGS2,EPHX2,LYN,SPAG5,FANCI,CDKN2C,OIP5,IRF4,NUP210,EIF4A3,KIF14,CDC25B,PLCL2,RFC3,PTPN18,PRIM2,TACC1,RAD51AP1,CAMSAP1,RRM2,EMP3,C14orf132,MCL1,BRCA1,CCNF,PRIM1,TRIM26,PDLIM1,DTX4,CCDC69,CTSA,ANP32E,CHEK2,CDK2,MAPK1,ESPL1,ADAM23 |
| 1.690e-02 | -4.08 | GSE15930_NAIVE_VS_72H_IN_VITRO_STIM_TRICHOSTATINA_CD8_TCELL_UP | MSigDB lists | GSE15930_NAIVE_VS_72H_IN_VITRO_STIM_TRICHOSTATINA_CD8_TCELL_UP | 190 | 40 | 17377 | 2626 |
RECQL,PIGN,KLHL21,RAE1,ALKBH5,BRAP,PCSK7,B4GALT1,HCFC1R1,SPR,C19orf48,GGPS1,SYNRG,ANKIB1,EEF2K,ZKSCAN1,SIAH1,CLTB,USP34,TRAFD1,TMEM115,TIMP2,FOXK1,DDX24,WBP1,AZI2,ICAM2,EIF4H,RAB5B,POLG2,USP21,BSDC1,PI4K2A,TSC1,SURF4,RBMS1,CANT1,DVL1,NCOA1,BRWD3 |
| 1.690e-02 | -4.08 | GSE43955_TGFB_IL6_VS_TGFB_IL6_IL23_TH17_ACT_CD4_TCELL_52H_DN | MSigDB lists | GSE43955_TGFB_IL6_VS_TGFB_IL6_IL23_TH17_ACT_CD4_TCELL_52H_DN | 190 | 40 | 17377 | 2626 |
SLC12A7,EBNA1BP2,CDIPT,RGS2,KIF5B,CLIC4,UCHL5,FJX1,ANXA5,YBX1,MDFIC,MTPN,CGGBP1,ALDH9A1,CYFIP1,FOXK1,BIRC3,ZMYND11,PPIE,MKI67,CUL3,WIPF1,TOR1AIP2,TMEM147,PLEC,ZFAND5,ASF1B,ZFR,GNAS,ZNF282,PEX5,PTER,TFDP1,PRDX5,EXOC4,RNF38,DTD1,RBBP4,CPEB2,PRPF4B |
| 1.690e-02 | -4.08 | GSE3982_NEUTROPHIL_VS_CENT_MEMORY_CD4_TCELL_UP | MSigDB lists | GSE3982_NEUTROPHIL_VS_CENT_MEMORY_CD4_TCELL_UP | 190 | 40 | 17377 | 2626 |
RHOG,CYTIP,PLXNC1,TMBIM4,RPS6KA1,FAM129A,RRAGC,HAUS4,ZNF267,DAZAP2,ATP6V1B2,MAP1LC3B,GNB2,GIT2,HLA-A,CFLAR,KIF5B,APLP2,PTEN,PELO,ZCCHC2,ZNF200,CYB5R1,IMPA2,MYO5A,FTL,TRIM8,RAB7A,NQO2,CUL3,E2F3,PFKFB3,KLF6,STK17B,SH3GLB1,RHBDF2,PPP2R5A,OSBPL8,IMPDH1,NCOA1 |
| 1.690e-02 | -4.08 | GSE36826_NORMAL_VS_STAPH_AUREUS_INF_SKIN_DN | MSigDB lists | GSE36826_NORMAL_VS_STAPH_AUREUS_INF_SKIN_DN | 190 | 40 | 17377 | 2626 |
SLC12A7,UBL3,UGP2,KIAA0100,CASP6,NDUFA4,NENF,MAN1A1,GNS,CD59,PRKD3,EFCAB11,SUCLG2,AHCY,RNF19A,UBE3B,GPD1L,ZC3H3,GM2A,ALDH9A1,TMEM160,ABCC5,TIMP2,CREG1,PBXIP1,RAD51AP1,SLC17A5,NDRG3,MAT2A,ANKRD46,SLC38A7,APPL2,WDR7,ACAT1,RBMS1,MDH1,SCARB1,TRIM32,CD81,ABCA1 |
| 1.690e-02 | -4.08 | GSE360_DC_VS_MAC_B_MALAYI_HIGH_DOSE_UP | MSigDB lists | GSE360_DC_VS_MAC_B_MALAYI_HIGH_DOSE_UP | 190 | 40 | 17377 | 2626 |
WSB2,TCF12,NCOR2,MPHOSPH8,ADO,KIAA0232,ENSA,MYH9,KLC1,CYCS,AP1B1,SPR,SLC25A36,HNRNPA2B1,TFAP4,ATIC,MCM5,ANP32A,MAP3K14,NUDC,SPTAN1,CSNK1G2,MAPKAPK3,PRKDC,TUFM,ATXN1,KCNQ1,PLEC,ICMT,H2AFV,PICALM,EPB41,PPP2CA,ADSS,CSK,LY75,DDX5,RBPJ,YWHAH,DDX52 |
| 1.690e-02 | -4.08 | GSE31622_WT_VS_KLF3_KO_BCELL_DN | MSigDB lists | GSE31622_WT_VS_KLF3_KO_BCELL_DN | 190 | 40 | 17377 | 2626 |
KIF3B,FEZ2,MCM10,MZT1,ADD1,DAP,PTTG1,CERK,STARD7,SMARCA4,GGPS1,CRLF3,CMTM6,SPPL2A,GART,NFATC3,TIMELESS,MARCH2,RNF135,MVP,MCMBP,FBXL19,SRSF10,NAGPA,NRAS,RBM42,DDX24,PFKFB3,USP10,MCL1,WDR81,GALNT7,DHX16,TPP2,E2F4,PLOD3,BRWD3,E2F2,LRP8,RAB3IL1 |
| 1.690e-02 | -4.08 | GSE1448_CTRL_VS_ANTI_VBETA5_DP_THYMOCYTE_DN | MSigDB lists | GSE1448_CTRL_VS_ANTI_VBETA5_DP_THYMOCYTE_DN | 190 | 40 | 17377 | 2626 |
RHOG,IER2,HSPH1,CYTIP,GNPNAT1,ST13,RPS6KA1,DYNLL1,LANCL1,RGS2,PRKACA,USF1,FGFR3,RNFT1,LPIN2,MDFIC,RNF19A,CNN2,GM2A,LUC7L2,POU2AF1,TRAFD1,MAPRE2,ERF,ILF3,GBA,ITM2A,DNAJA1,SEPT7,PSMB9,IRF5,HLA-B,PLD3,STAT6,PRDX5,MAPK6,ATF6,TSPAN5,LONP2,PFKP |
| 1.690e-02 | -4.08 | GSE41176_UNSTIM_VS_ANTI_IGM_STIM_BCELL_1H_DN | MSigDB lists | GSE41176_UNSTIM_VS_ANTI_IGM_STIM_BCELL_1H_DN | 190 | 40 | 17377 | 2626 |
UFC1,TMX4,HEXB,TAP1,MCCC1,COX4I1,HAUS4,CCDC28A,C1GALT1,PCNA,ARF5,MBD2,SOCS6,FAM89B,MVP,KCNAB2,RNF5,SLC25A1,RPL29,TIMP2,LAP3,TMEM126B,DENND1B,RFXANK,MAP4K3,SEPT7,ICAM2,PSMB9,MYO1F,HHEX,SCARB2,OSBPL11,QARS,PRPS2,ARNTL,STAT1,PSAP,WIPI2,LTA4H,IFI16 |
| 1.690e-02 | -4.08 | GSE40273_GATA1_KO_VS_WT_TREG_DN | MSigDB lists | GSE40273_GATA1_KO_VS_WT_TREG_DN | 190 | 40 | 17377 | 2626 |
CCDC93,CTU2,PLXNC1,ANKH,IRF3,DOCK11,CCDC28A,KIAA1147,SLC25A37,PHC2,VASP,ADD3,ZNF639,CISD2,CREB1,LPCAT1,SPTAN1,SNX8,VOPP1,CYTH1,ARHGAP17,BIRC3,LNX2,PACS1,NFATC2,MAP4K3,PLEC,STX16,MBIP,JAK1,PDLIM1,HNRNPH3,PROSER1,ATE1,NCOA1,FAM208A,PURA,TIGD2,SNAPIN,LRCH1 |
| 1.690e-02 | -4.08 | GSE39820_CTRL_VS_IL1B_IL6_IL23A_CD4_TCELL_DN | MSigDB lists | GSE39820_CTRL_VS_IL1B_IL6_IL23A_CD4_TCELL_DN | 190 | 40 | 17377 | 2626 |
CMAS,CDS2,LIME1,GMFG,CASP6,SEC61G,CAST,SRGN,GADD45G,FLOT1,SLC35B1,DUSP22,ZADH2,PAIP2,PPP1R3B,MDM2,NEK6,MED10,ETV6,INTS12,PDIA6,S100A6,DRAM2,CSNK1G3,PTPRK,RFC3,GALC,RAB1A,CYFIP2,SH3GLB1,AMZ2,GOLGA7,NSF,TWSG1,APPL2,ARAP1,CRCP,ATF6,EHD4,FAU |
| 1.690e-02 | -4.08 | GSE20715_0H_VS_6H_OZONE_TLR4_KO_LUNG_DN | MSigDB lists | GSE20715_0H_VS_6H_OZONE_TLR4_KO_LUNG_DN | 190 | 40 | 17377 | 2626 |
UBE2D3,TOMM20,THOC1,GPBP1L1,UBR2,SHPRH,C16orf87,STARD7,ZFYVE21,CHD1,FAM8A1,CDC73,PAIP1,VMP1,AFF1,NUP153,TARDBP,S100A6,SHOC2,MAPRE2,ELL2,TMEM216,MTMR6,THNSL1,ADRB2,HAGH,KLF6,SERP1,CYB5A,IDE,RAB24,RPS14,USP20,LY75,ATF6,DDX5,CHPF2,TSPAN5,OAZ1,CCDC137 |
| 1.692e-02 | -4.08 | ATP2A2 (ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2) | protein interactions | 488 | 81 | 21 | 17029 | 2761 |
UNK,SUZ12,RAB7A,CUL3,PTP4A3,KIF23,NOTCH2,ADRB2,NDUFS4,DERL1,HGS,MDM2,ATP2A2,ZNF746,MBOAT1,XRCC3,BCL2,CLN3,LMAN1,ATF2,PTPRK |
| 1.692e-02 | -4.08 | UPK1A (uroplakin 1A) | protein interactions | 11045 | 81 | 21 | 17029 | 2761 |
NAT14,ZDHHC18,PIGM,NDC1,ABCA3,ERMP1,TMEM39A,GPR89A,CIB1,LETMD1,LRRC8A,ABCB10,SLC29A1,SLC12A9,SPPL2B,XPR1,TMEM179B,LEMD2,CERS6,SLC44A1,TMEM219 |
| 1.692e-02 | -4.08 | HP1BP3 (heterochromatin protein 1 binding protein 3) | protein interactions | 50809 | 81 | 21 | 17029 | 2761 |
IMMT,NOP2,SUZ12,SUMO2,CUL3,CUL1,RPS24,NUSAP1,BRCA1,VDAC1,HMG20A,APP,LMNA,CAND1,SURF4,RPS14,ZNF326,FTSJ3,ZC3HAV1,IFI16,NIPSNAP1 |
| 1.692e-02 | -4.08 | P4HA2 (prolyl 4-hydroxylase subunit alpha 2) | protein interactions | 8974 | 81 | 21 | 17029 | 2761 |
CCT2,TSC2,TSPYL4,ERF,PRRC2A,NEK7,CHTF18,SCYL1,TIGD5,MAP7D1,SEC16A,TRIM65,KIF18B,FAAP100,H2AFX,GTSE1,TRIM32,DMWD,WDR62,MYO9A,CPSF4 |
| 1.692e-02 | -4.08 | KIM_MYCL1_AMPLIFICATION_TARGETS_DN | MSigDB lists | KIM_MYCL1_AMPLIFICATION_TARGETS_DN | 19 | 7 | 17377 | 2626 |
KIF3B,AHNAK,NRAS,ANLN,OAT,CMTM6,PHTF1 |
| 1.692e-02 | -4.08 | GO_CLEAVAGE_INVOLVED_IN_RRNA_PROCESSING | MSigDB lists | GO_CLEAVAGE_INVOLVED_IN_RRNA_PROCESSING | 19 | 7 | 17377 | 2626 |
UTP20,EXOSC9,EXOSC7,RRS1,ERI3,RPSA,RRP36 |
| 1.692e-02 | -4.08 | PID_ARF_3PATHWAY | MSigDB lists | PID_ARF_3PATHWAY | 19 | 7 | 17377 | 2626 |
ARFIP2,USO1,ARF1,COPA,CLTB,RAC1,KDELR1 |
| 1.692e-02 | -4.08 | GO_NUCLEOTIDE_TRANSMEMBRANE_TRANSPORTER_ACTIVITY | MSigDB lists | GO_NUCLEOTIDE_TRANSMEMBRANE_TRANSPORTER_ACTIVITY | 19 | 7 | 17377 | 2626 |
SLC25A19,SLC35B1,SLC35B2,SLC35A1,SLC25A33,SLC35B4,SLC25A36 |
| 1.692e-02 | -4.08 | GO_N_GLYCAN_PROCESSING | MSigDB lists | GO_N_GLYCAN_PROCESSING | 19 | 7 | 17377 | 2626 |
MAN2A2,EDEM2,ST8SIA2,PRKCSH,MAN1B1,FUT8,MAN1A1 |
| 1.692e-02 | -4.08 | GO_NEGATIVE_REGULATION_OF_MRNA_SPLICING_VIA_SPLICEOSOME | MSigDB lists | GO_NEGATIVE_REGULATION_OF_MRNA_SPLICING_VIA_SPLICEOSOME | 19 | 7 | 17377 | 2626 |
HNRNPA2B1,RBM42,RBMX,SRSF6,SRSF4,SRSF10,RNPS1 |
| 1.692e-02 | -4.08 | MODULE_320 | MSigDB lists | MODULE_320 | 19 | 7 | 17377 | 2626 |
KIF23,BRCA1,SMC2,KIF11,ESPL1,PTTG1,ILF3 |
| 1.692e-02 | -4.08 | GO_PROTEIN_PHOSPHATASE_1_BINDING | MSigDB lists | GO_PROTEIN_PHOSPHATASE_1_BINDING | 19 | 7 | 17377 | 2626 |
SHOC2,PPP1R9B,PAWR,STAU1,KCNQ1,LMNA,CDC5L |
| 1.692e-02 | -4.08 | GO_MATURATION_OF_5_8S_RRNA_FROM_TRICISTRONIC_RRNA_TRANSCRIPT_SSU_RRNA_5_8S_RRNA_LSU_RRNA_ | MSigDB lists | GO_MATURATION_OF_5_8S_RRNA_FROM_TRICISTRONIC_RRNA_TRANSCRIPT_SSU_RRNA_5_8S_RRNA_LSU_RRNA_ | 19 | 7 | 17377 | 2626 |
UTP20,EXOSC9,EXOSC7,RRS1,ERI3,FTSJ3,RPSA |
| 1.692e-02 | -4.08 | SEIDEN_MET_SIGNALING | MSigDB lists | SEIDEN_MET_SIGNALING | 19 | 7 | 17377 | 2626 |
TM9SF3,KIF2A,CLCN3,API5,RAB11A,CCT8,PRPS2 |
| 1.692e-02 | -4.08 | GO_NEGATIVE_REGULATION_OF_PROTEIN_TYROSINE_KINASE_ACTIVITY | MSigDB lists | GO_NEGATIVE_REGULATION_OF_PROTEIN_TYROSINE_KINASE_ACTIVITY | 19 | 7 | 17377 | 2626 |
PTPN2,SH3BP5,FGFR1OP,MVP,PSEN1,SOCS4,SOCS5 |
| 1.692e-02 | -4.08 | LI_WILMS_TUMOR_ANAPLASTIC_UP | MSigDB lists | LI_WILMS_TUMOR_ANAPLASTIC_UP | 19 | 7 | 17377 | 2626 |
NUSAP1,KPNA2,KIF2C,RFC3,CENPF,CDCA3,MKI67 |
| 1.692e-02 | -4.08 | GO_MACROMOLECULE_TRANSMEMBRANE_TRANSPORTER_ACTIVITY | MSigDB lists | GO_MACROMOLECULE_TRANSMEMBRANE_TRANSPORTER_ACTIVITY | 19 | 7 | 17377 | 2626 |
MCL1,TOMM20,TOMM40,TIMM23,SEC61G,TIMM17A,TFRC |
| 1.694e-02 | -4.08 | dsRNA fragmentation | biological process | GO:0031050 | 32 | 10 | 17256 | 2622 |
HNRNPA2B1,SMAD2,DGCR8,ZC3H7B,AGO2,PRKRA,SMAD1,SRRT,METTL3,TUT4 |
| 1.694e-02 | -4.08 | cellular senescence | biological process | GO:0090398 | 32 | 10 | 17256 | 2622 |
ULK3,NSMCE2,ARNTL,PML,H2AFX,SMC6,MAPK14,HRAS,CDKN2A,TERF2 |
| 1.694e-02 | -4.08 | RNA polyadenylation | biological process | GO:0043631 | 32 | 10 | 17256 | 2622 |
PAF1,GRSF1,CPSF4,AHCYL1,SYMPK,APP,PABPC1,CDC73,ZC3H3,PAPOLA |
| 1.694e-02 | -4.08 | microtubule polymerization | biological process | GO:0046785 | 32 | 10 | 17256 | 2622 |
ZNF207,MZT1,GOLGA2,CENPJ,PIN1,TUBGCP5,NDE1,TUBGCP2,CSNK1D,FBXO5 |
| 1.694e-02 | -4.08 | G2 DNA damage checkpoint | biological process | GO:0031572 | 32 | 10 | 17256 | 2622 |
DTL,PLK1,BABAM2,CLSPN,TAOK1,BABAM1,MRNIP,BRCA1,BLM,FANCI |
| 1.694e-02 | -4.08 | ATP hydrolysis coupled transmembrane transport | biological process | GO:0090662 | 32 | 10 | 17256 | 2622 |
ATP6V0B,ATP1A1,ATP5MC3,ATP6V0A2,ATP6V0A1,ATP6V0C,ATP6V1C1,ATP6V1B2,ATP6V0E1,ATP6V0D1 |
| 1.694e-02 | -4.08 | regulation of cell cycle checkpoint | biological process | GO:1901976 | 32 | 10 | 17256 | 2622 |
RFWD3,RPA2,THOC1,CDT1,FEM1B,XRCC3,CHEK2,WDR76,CCNB1,GEN1 |
| 1.694e-02 | -4.08 | global genome nucleotide-excision repair | biological process | GO:0070911 | 32 | 10 | 17256 | 2622 |
ERCC1,RBX1,RPS27A,SUMO2,XPA,RAD23B,CHD1L,UBE2I,GTF2H2,DDB1 |
| 1.694e-02 | -4.08 | production of small RNA involved in gene silencing by RNA | biological process | GO:0070918 | 32 | 10 | 17256 | 2622 |
HNRNPA2B1,SMAD2,DGCR8,ZC3H7B,AGO2,PRKRA,SMAD1,SRRT,METTL3,TUT4 |
| 1.696e-02 | -4.08 | transferase activity, transferring acyl groups | molecular function | GO:0016746 | 254 | 52 | 17224 | 2647 |
NAT14,NAT9,GNPNAT1,ZDHHC8,AGPAT1,AGPAT3,TAF6L,WDR5,SUPT7L,LCLAT1,CRAT,ZDHHC13,NAA50,HADHB,CS,TAF5L,KANSL2,SPTSSA,ATF2,LPCAT1,SMARCE1,NAA35,ELOVL5,ZDHHC18,KAT2A,KAT7,ELP4,EDF1,USP22,KMT2C,TAZ,PDHX,ZDHHC3,NMT2,ABHD5,AGPAT2,GOLGA7,CERS6,TEX30,LPCAT4,ACLY,OGT,ATE1,ACAT1,ZDHHC7,MBOAT1,TAF12,NCOA1,NAA20,OSGEPL1,SAT2,NAA60 |
| 1.697e-02 | -4.08 | GO_REGULATION_OF_PROTEIN_TARGETING | MSigDB lists | GO_REGULATION_OF_PROTEIN_TARGETING | 287 | 57 | 17377 | 2626 |
DDX58,UBE2D3,ZBED3,CYLD,TXN,CHERP,NF1,ZDHHC8,ANK3,CIB1,NUP54,STARD7,RAB23,PLAGL2,PPP3CB,MAPK14,CDK5,HUWE1,PIK3R2,SRI,AXIN2,FAM89B,PARL,ATG13,MDFIC,MAVS,CYB5R1,OGG1,HTRA2,TGFB1,PPP3CA,RHOA,KAT2A,AKT2,PSMB7,BRCA1,NUTF2,TRIM28,SH3GLB1,USP36,PRDX1,AKAP1,NUCB1,KEAP1,KPNA1,TONSL,PSMD8,AXIN1,OGT,PPP3R1,NUP62,PKD2,ZNF268,PARP10,SMAD4,CDKN2A,FAF1 |
| 1.697e-02 | -4.08 | FARMER_BREAST_CANCER_BASAL_VS_LULMINAL | MSigDB lists | FARMER_BREAST_CANCER_BASAL_VS_LULMINAL | 316 | 62 | 17377 | 2626 |
CCNC,TBC1D12,CHMP2A,MCM10,NQO1,FOXM1,TSC22D3,PTTG1,KIAA0232,TPX2,C5orf30,ITGB5,LYN,REEP5,PRNP,PRKD3,CLIC4,LRRC8D,MCM5,IL6ST,KIF14,FUT8,EFCAB11,YBX1,BCL2,FBXL7,GPD1L,FAM171A1,LDHB,IFRD1,NCK1,NUDT4,RAD51AP1,AMD1,LRBA,CIRBP,E2F3,GTPBP4,HEBP2,GALNT7,RHOB,MAGED2,VEZF1,MTHFD2,AHNAK,SYNCRIP,RBM47,TTLL4,CERS6,CORO1C,U2SURP,NFIL3,CEBPG,SLC16A1,CANT1,MRFAP1L1,GALNT10,TOB1,LONP2,PFKP,CDKN2A,HDAC2 |
| 1.698e-02 | -4.08 | phospholipid biosynthetic process | biological process | GO:0008654 | 274 | 55 | 17256 | 2622 |
RAB14,PIGM,CDS2,PIGN,PIGQ,HEXB,AGPAT1,STARD7,CSNK2A1,AGPAT3,ARF1,CHKB,CDIPT,PMVK,LCLAT1,GGPS1,RUFY1,PIP4K2A,CPNE3,PIP5K1C,CHKA,FGFR3,PDXP,NUS1,PYURF,MTMR4,PTEN,PIK3R2,SLC44A1,RAB4A,LPIN2,PTPN11,PIGG,PCYT2,PIKFYVE,LPCAT1,GPD1L,PGAP2,CPNE1,PIGT,DPM1,PGS1,PIP4K2C,MTMR6,MTMR12,TAZ,PI4K2A,ABHD5,MTMR3,AGPAT2,LPCAT4,MBOAT1,SAMD8,CHPT1,PTDSS1 |
| 1.701e-02 | -4.07 | YAGI_AML_WITH_INV_16_TRANSLOCATION | MSigDB lists | YAGI_AML_WITH_INV_16_TRANSLOCATION | 404 | 77 | 17377 | 2626 |
IMMT,HNRNPAB,RPLP2,NF1,MDH2,TMEM109,CUL1,FKBP2,S1PR2,PPP1R16B,LYN,CHD1,RPL23A,PRNP,KRR1,KIFC1,OIP5,DUS4L,SAR1A,MTMR4,HADHB,BAZ2A,AKT2,EZR,DIDO1,CBFB,H2AFV,DPYSL3,RPL37,RAD51C,UBXN2B,PPM1G,RPLP1,XRCC4,TRAF5,LRP8,ATP6V0E1,PFKP,CSNK1D,CDC40,TM9SF4,CDK2AP2,NACA,ARID5A,KIF23,SRRT,COPB2,SAC3D1,GNS,RPN1,NFATC3,PPIL2,RBM3,SLC38A10,BCL2,RPL19,PABPC1,MSH6,RBM15B,CYTH1,RHOA,ETV3,RB1CC1,TACC1,BTAF1,ITM2A,ARHGEF12,LY6E,RPL27A,ZDHHC3,ECH1,CAT,RBM25,RPL32,ACOX1,PKD2,UBE2C |
| 1.702e-02 | -4.07 | human chr15q24.2 | chromosome location | human chr15q24.2 | 26 | 7 | 26185 | 2809 |
RPP25,COX5A,UBE2Q2,SNUPN,COMMD4,FBXO22,PPCDC |
| 1.706e-02 | -4.07 | V$USF_Q6_01 | MSigDB lists | V$USF_Q6_01 | 224 | 46 | 17377 | 2626 |
PRPF38B,RPS2,MAX,DNMT3A,NDUFS1,EWSR1,ADAM10,GADD45G,GYG1,TAF6L,SNN,STMN1,GNB2,SSR1,TFAP4,EFTUD2,YBX1,RPL19,SLC26A2,CCAR1,SOCS5,RLIM,EIF5A,NRAS,LONRF3,AATF,WDR1,WBP2,ILF3,ELK1,KRTCAP2,PICALM,HMGN2,GNAS,TMED10,HPS5,HNRNPH3,MRPL27,DCAF11,MPV17,SLC16A1,CLN3,HEXA,RAB3IL1,SLC25A33,ADNP2 |
| 1.709e-02 | -4.07 | PEDERSEN_METASTASIS_BY_ERBB2_ISOFORM_7 | MSigDB lists | PEDERSEN_METASTASIS_BY_ERBB2_ISOFORM_7 | 357 | 69 | 17377 | 2626 |
SNX27,SKA3,SP100,DUT,RNASEH2A,CLTB,RBM12B,GPD1L,SAP30L,SAP30,ERCC1,PPP1R18,RAD51AP1,KIF15,EZR,H2AFV,ZFAND5,SRSF1,PRIM1,MAFK,ZNF689,STAT1,H2AFX,ITGB1,ADAM9,GALNT10,SMURF1,GLCCI1,GEN1,NDUFS1,SH2D3A,SDC2,DLGAP4,HAUS4,HMGN3,PXMP2,B4GALT4,NCAPG,ITGB5,RAPGEF6,RMI1,HLA-A,CFLAR,CD59,ADD3,KLHL5,SLC1A4,PHF14,RBM3,CENPM,TMEM8A,SLC35A1,HMGN5,GALC,ASPM,NET1,CCDC34,RIT1,KIF11,KLF6,PDE3B,APPL1,SH3BP5,HLA-B,GALNT2,NAP1L1,ETS2,RBMX,NR2F2 |
| 1.710e-02 | -4.07 | histone acetyltransferase complex | cellular component | GO:0000123 | 83 | 20 | 18223 | 2701 |
KAT2A,KAT7,ELP4,SUPT20H,TAF6L,USP22,WDR5,SUPT7L,MEAF6,TAF2,MBIP,BRPF3,OGT,TAF5L,KANSL2,ACTB,TAF12,RUVBL2,TAF6,SGF29 |
| 1.715e-02 | -4.07 | GO_INTRACELLULAR_VESICLE | MSigDB lists | GO_INTRACELLULAR_VESICLE | 1203 | 208 | 17377 | 2626 |
RAB14,TMED7,PDCD6IP,COPA,ADAM10,ZDHHC8,SNX15,HEXB,AP3M2,TGOLN2,AGFG1,SND1,UBQLN2,MAP1LC3B,BECN1,SYNRG,DST,RAB8A,CDC42,AP3S2,RAB35,RAB4A,AP1M1,SRI,DNM2,AP2B1,RP2,MARCH2,USO1,ATG9A,AKT2,ARHGDIB,SLC17A5,MCFD2,RAB5B,RAB22A,PLEKHF2,OPTN,NECAP2,DPYSL3,CXXC4,TBC1D17,TMED10,RPS27A,AXIN1,PRDX5,ITGB1,OGT,CRCP,ARRDC1,ATP6V0C,CLU,DVL1,CLN3,ARRB2,ATP6V0E1,ANXA11,NUMB,PPIB,HSPH1,DNAJC5,AGTRAP,HLA-E,NKD2,RAB23,KLC1,RACGAP1,TMED3,RAB6A,PSEN1,APH1B,ITGB5,RAPGEF6,COPG2,COPB2,CD59,RPN1,ZNRF2,SNX18,RINL,ORAI1,ATP6V0A2,AHCY,PIKFYVE,ATP6V0D1,SYTL3,TMED2,KDELR1,VOPP1,PIGT,GOSR1,PI4K2A,FAS,SEC31A,GNAS,NAP1L1,TMEM168,GOLGA2,SNAP23,ARAP1,YWHAZ,HEXA,EXOC3,ANKRD27,CORO7,ABCA3,GGNBP2,TRAF7,RAB11B,SLC2A1,COPE,RAC1,VTI1A,ZFYVE21,BCL2L1,AP1B1,ATP6V1B2,BCAP31,APP,RAB21,ATP6V0B,APLP2,MDM2,SCAMP4,CORO1A,CYB5R1,CLTB,LMAN1,PDIA6,DVL2,EBAG9,CLCN3,UBQLN4,PPT1,RAB7A,GOPC,SLC26A6,VDAC2,ATP6V0A1,WIPF1,BICD2,VDAC1,RAB1A,CHMP4A,ATP1A1,SURF4,SCAP,CLK3,WDR7,AP1S1,ANP32E,TICAM1,SCARB1,AP2S1,ABCA1,TMEM33,GOLIM4,ANXA6,SRGN,SCYL1,TMX3,FLOT1,CHIC2,ARF1,GGA2,AP3S1,RAB11A,SCYL2,MFSD10,TFRC,HLA-A,FZD6,SPPL2A,KIF5B,HERC3,FGFR3,CLIC4,SLC1A4,SEC24C,ZDHHC13,AXIN2,ARHGEF2,ANXA5,MYO5A,CAMK2G,PDPK1,TGFB1,ACP2,DENND4C,DENND1B,PACS1,KCNQ1,ZP3,SPPL2B,PICALM,SH3GLB1,NEU1,PRDX1,HLA-B,NUCB1,PDCD6,SEC23IP,SNAP29,WNT5B,FAM3C,ATP6V1C1,YWHAH,SNAPIN |
| 1.718e-02 | -4.06 | GSE23984_CTRL_VS_HYPOCALEMIC_VITAMIND_ANALOG_TCELL_UP | MSigDB lists | GSE23984_CTRL_VS_HYPOCALEMIC_VITAMIND_ANALOG_TCELL_UP | 179 | 38 | 17377 | 2626 |
MIF,MAPRE1,GPR132,TXN,WDYHV1,MDH2,UQCR10,C19orf25,STARD7,SLC25A12,PSEN1,PMVK,APP,PARK7,NUDT19,NUS1,VMP1,TANK,CNPY4,CS,PARL,ARL5A,SLC25A1,CCT2,VHL,AACS,PPP1R21,ABHD11,OGDH,ODC1,ALDH3B1,MTHFD2,MEGF9,ATP6V0C,CCDC125,AP2S1,TUBB,VPS29 |
| 1.718e-02 | -4.06 | GSE14350_TREG_VS_TEFF_IN_IL2RB_KO_DN | MSigDB lists | GSE14350_TREG_VS_TEFF_IN_IL2RB_KO_DN | 179 | 38 | 17377 | 2626 |
TMEM106C,SKA3,PRKCSH,C1orf112,SESTD1,TKT,RRM1,RACGAP1,SDF2L1,PMVK,TFRC,FZD6,PCYOX1L,OIP5,MRPL54,KIF22,KNTC1,UBE2M,DNMT1,TMEM160,SNX25,MLEC,POLK,MAP7D1,TOMM40,KIF11,ASF1B,MAPK3,PRIM1,POLE,TONSL,CDCA5,DBI,PML,KHSRP,CENPT,HRAS,ESPL1 |
| 1.718e-02 | -4.06 | GSE22886_NAIVE_CD4_TCELL_VS_48H_ACT_TH2_UP | MSigDB lists | GSE22886_NAIVE_CD4_TCELL_VS_48H_ACT_TH2_UP | 179 | 38 | 17377 | 2626 |
RPLP2,TSC22D3,EIF3D,CUTA,PTP4A3,SNN,RSAD1,SLC25A37,SLC25A36,ANKRD28,ADD3,RPL17,BCL2,AHDC1,CRY2,TTC3,PABPC1,DVL2,LARS,RPL29,KAT2A,ETV3,RPL8,CIRBP,MFNG,PLEC,PRMT2,RPS9,RBM38,TRAM2,SCARB2,RPL32,ACBD4,LY75,DVL1,FAU,CBX4,RNF114 |
| 1.718e-02 | -4.06 | GSE36392_TYPE_2_MYELOID_VS_EOSINOPHIL_IL25_TREATED_LUNG_DN | MSigDB lists | GSE36392_TYPE_2_MYELOID_VS_EOSINOPHIL_IL25_TREATED_LUNG_DN | 179 | 38 | 17377 | 2626 |
CDS2,LYRM4,PHF23,GSPT2,MED13L,DHX8,SIRT2,SLC25A44,RLF,MIEN1,CMTM6,C18orf32,ZNF473,NEK6,SNX18,CREB1,RNF135,RPRD1B,CARM1,TCTEX1D2,ANKRD37,ATG9A,MCL1,PICALM,SFXN5,ISG15,PLEKHF2,POLR2A,AGPAT2,FBXO28,ETS2,GADD45B,NFIL3,FAM122A,FKBP5,PDLIM5,ADNP2,SVIP |
| 1.719e-02 | -4.06 | DNAJB11 (DnaJ heat shock protein family (Hsp40) member B11) | protein interactions | 51726 | 86 | 22 | 17029 | 2761 |
UBQLN4,ACP2,CYLD,DRAP1,EIF3D,UBXN1,CUL3,RRM1,NADK2,SDF2L1,MAN2B1,ADRB2,BORA,SDHA,ECH1,ANKZF1,NDUFV1,CORO1C,GTSE1,POT1,FAF1,TERF2 |
| 1.719e-02 | -4.06 | PRKAR1A (protein kinase cAMP-dependent type I regulatory subunit alpha) | protein interactions | 5573 | 86 | 22 | 17029 | 2761 |
RAF1,AGO2,PRKAR1B,CUL3,MEN1,PRKACA,RFC2,HLA-A,PLEKHF2,STOML2,AKAP1,ANKRD26,PFDN5,SMAD2,SLC38A5,SAFB,MAPK6,YWHAZ,CDK2,SMURF1,UBE2M,IFI16 |
| 1.720e-02 | -4.06 | transcription factor complex | cellular component | GO:0005667 | 346 | 66 | 18223 | 2701 |
RORB,TCF12,MAX,TRERF1,HNRNPAB,IVNS1ABP,TAF6L,RCOR3,SNAPC4,CREM,USF1,CD3EAP,TAF5L,TCEA1,CARM1,POU2AF1,DEAF1,ERCC1,RIOX2,E2F3,NFATC2,EDF1,SOX4,TRIM28,TAF2,SMAD2,RBL1,E2F4,HIPK2,ARNTL,SMAD1,TFDP2,E2F2,SMAD4,POU3F2,TCF3,MEF2A,PMF1,ETS1,GTF2F1,RB1,SUB1,NFATC3,MED10,MED8,CREB1,GTF2H2,STAT3,GTF3C6,KAT2A,CREG1,PRKDC,MTA2,LDB1,RCOR1,PRMT2,PDLIM1,TFDP1,PITX1,TBPL1,E2F1,TAF12,RBPJ,YY1,TAF6,CDK2 |
| 1.721e-02 | -4.06 | regulation of cofactor metabolic process | biological process | GO:0051193 | 102 | 24 | 17256 | 2622 |
NDC1,NUP188,RAE1,RAC1,PRKAA1,NUP54,PFKFB3,NUP155,PDHX,NUP205,PDK2,NUP210,TIGAR,NUP107,OGT,NUP62,NUP153,ECD,STAT3,PGAM1,NUP85,NUP58,AAAS,SEH1L |
| 1.722e-02 | -4.06 | SCF(Skp2)-mediated degradation of p27/p21 | REACTOME pathways | R-HSA-187577 | 61 | 17 | 10287 | 1696 |
PSMB7,PSMA1,CUL1,PSMB9,PSMD9,PSMB3,PSMC4,PSMD2,PSMA6,CCNA2,PSMD1,RPS27A,PSMD3,PSMD8,CDKN1B,CDK2,PSMC1 |
| 1.722e-02 | -4.06 | Dectin-1 mediated noncanonical NF-kB signaling | REACTOME pathways | R-HSA-5607761 | 61 | 17 | 10287 | 1696 |
PSMA8,PSMB7,PSMA1,CUL1,PSMB9,PSMD9,PSMB3,PSMC4,PSMD2,PSMA6,PSMD1,RPS27A,PSMD3,PSMD8,MAP3K14,UBE2M,PSMC1 |
| 1.724e-02 | -4.06 | HDL cholesterol(PMID:19060911) | GWAS genes | HDL cholesterol(PMID:19060911) | 5 | 3 | 2388 | 307 |
NUTF2,TOMM40,ABCA1 |
| 1.726e-02 | -4.06 | lung | COSMIC cancer mutations | lung | 16793 | 2517 | 17385 | 2587 |
HECA,ZBTB10,ABCC10,HEXB,TGOLN2,CCNL2,FBXO22,EEF2K,THAP4,RAD23B,ATP13A3,DNM2,FTSJ3,USP34,CCDC57,ERCC1,NRAS,EHMT1,KIF15,HNRNPF,WDHD1,MIER2,DIDO1,MCM2,RAB22A,SMAD2,MID1IP1,RPS27A,MYO18A,OGT,MPV17,COX5A,SMAD1,ZNF75A,ANXA11,SLC25A33,ZNF720,SEC61G,GGA1,MUM1,CCZ1,TRIO,CUTA,RAB23,KCTD17,HAUS4,EIF2AK4,APH1B,PARN,CDC73,MYL6B,ATG4A,TMEM179B,ERV3-1,PDXP,SMC3,C4orf3,GEMIN4,MVP,NUP85,PPP6R1,PABPC1,NSUN4,PPA1,IFRD1,AGGF1,FOXK1,RBM42,GTPBP4,MAP7D1,MRPL16,ELK1,EIF4H,RDH11,MAGED2,KPNA1,ETS2,TYW5,WIPI2,RUFY3,PDLIM5,ACSF2,FAM72D,EXOC3,RHOG,STARD7,C5orf30,VTI1A,SLC35B2,INO80E,LCLAT1,RCOR3,CPNE3,KIAA1147,RBM23,ZNF420,AHCTF1,TBC1D22A,TBC1D14,GMEB1,NSFL1C,SEPT11,GPD1L,ZC3H3,ARL5A,PDCL3,SNX8,ERMP1,IDH3A,POLR2D,HTATIP2,MEF2D,TMEM147,GSTCD,TANC1,MAT2A,VPS26B,CORO1C,NSMCE2,CAMKMT,PPP5C,PITRM1,TUBB,COMMD10,ZNF445,SRSF6,HABP4,CCM2,FLOT1,BTN3A1,ATG2B,ABHD14B,PPP1R3B,GOLM1,ZBTB45,HUWE1,ZNF260,ANXA5,LTN1,KANSL2,UBE3B,NAP1L4,ZNF710,ST8SIA2,RPL22L1,MED22,SPTAN1,STAU1,DDX24,TCTEX1D2,TACC1,MRS2,LDHA,HEBP2,LLPH,C14orf132,RAB3IP,TTC33,PICALM,SH3BP5,SLC19A1,ACOX1,FAM3C,AEN,PARP10,YWHAH,THAP5,GPATCH4,FAM129A,TRIM11,YTHDC2,SNX15,RBM8A,ENSA,NENF,SND1,RUFY1,TRIM65,ZER1,PRNP,KRR1,RAB8A,NUP210,NT5DC1,NOC2L,EIF5,TACC3,VPS13B,PTPN18,MIOS,MBLAC2,SNRPB,CDC6,UTP3,PBRM1,ODC1,USP21,TRAM2,FBXO28,BCL7C,ARRDC1,ADAM9,DVL1,NUMB,ZNF564,FUBP1,C1orf74,CTU2,PARP12,ZCCHC9,CENPF,LAMTOR3,CHCHD2,NCKAP1,LYRM2,RSAD1,TNS3,SUB1,RINL,SSBP3,KIF13B,MBD2,XPA,AHCY,RBM3,GLE1,LRSAM1,HDHD2,NSDHL,AMD1,CAMSAP1,ZNF761,METTL22,ICAM2,STYXL1,APPL1,BBS12,ANKRD46,RXRB,SDHB,PCM1,GALNT2,TMEM168,NLRC5,RUVBL2,MYO9A,BTBD10,CCNB2,USP7,GLT8D1,RPLP2,SUCLG1,ARID2,TMX4,SLC2A1,ATP6V1B2,PCBP1,LYN,BCAP31,VAV1,TMEM69,MRPL50,PSMA6,ZNF473,ZNF302,BRPF3,TARDBP,BCAP29,CTDSP2,PRPF19,PPIF,KDM3B,MND1,CLCN3,BIRC3,RAB7A,ANKRD33B,PPIE,CHMP2B,VDAC1,EIF3H,TMEM201,GLOD4,IDE,DHX16,UHRF2,CHMP4B,XRCC3,PARD3,BCL2L12,C19orf53,MCM10,KLHL21,PDAP1,CDCA8,TMX3,GTF3A,ARF1,SLC12A9,TUBGCP2,DNAJB9,HOMER1,POLR1B,RNF5,RBM15B,PPAN,RHOA,RPRD1A,BTAF1,TOP3A,ARHGEF12,PCGF1,DDX23,RAB18,CACNB1,TRIM26,PDCD6,ATP6V1D,L3MBTL3,FAM110A,NEIL3,CTBS,BBX,IMPDH1,TAF12,NR2F2,PGAM1,HIPK3,IFI16,NUP188,TXN,H2AFZ,PNISR,TMEM203,PRKCSH,USP39,UBE2I,PARK7,SLC25A37,ASPHD2,ZNF428,RAB4A,TRA2B,SUCLG2,TAF5L,CISD2,SMARCE1,ZNF800,CDC5L,ZNF524,SGCE,OSBP2,NSUN2,USP22,CLNS1A,EIF3A,ZMYM3,DOT1L,IWS1,ANKRD10,WAS,KIF18B,TPP2,C1orf109,ZMAT3,B4GALT2,PRPF38B,RECQL,C9orf78,EWSR1,GADD45G,RRM1,ACAP1,B4GALT1,CYCS,FAM136A,SUPT7L,NPLOC4,CNOT3,SPAG5,WDR48,RTKN,CEP104,EXOSC7,KLHL5,LRRC8D,PPP4R1,MSH2,PIGG,OSTF1,FBXL7,MRPL40,TNRC18,SYTL3,FAM171A1,APOL1,EIF5A,GCC2,PRIM2,ELL2,RDH10,MFNG,RPS24,GORASP2,CAPZA2,ADRB2,CCT8,MTR,PHF6,PFDN5,SLCO4A1,TTC13,GOLGA2,RBMX,MED15,PIAS2,APPL2,SAMD8,NUDT3,CDKN2A,ZNF511,ATXN3,RAF1,KIAA0232,C2orf49,CD320,EPM2A,CCNA2,MTMR4,BRI3,TP53BP2,AQR,RBM12B,ILKAP,CDK12,SAP30,BRD4,DRAP1,NARF,LRRC8A,ELP4,ABHD11,PKMYT1,ASB13,SERP1,TRIM28,SUPT16H,EIF3K,CHMP4A,CBWD1,ATF6,XRCC4,ADAM23,PRPF4B,NDUFS1,DEPDC1,MECP2,SECISBP2,HMG20A,WWP2,JAKMIP1,SLC25A36,CCNK,DNAJC8,AXIN2,CITED2,JMJD4,ANKRD37,KAT2A,TMEM126B,RABIF,ADSL,PACS1,BMS1,KCNQ1,OTUD3,ARSK,MACF1,KIF11,KLF6,COMMD4,SMAP2,FADD,SH3GLB1,MYO1F,CBX3,TMEM127,INF2,PPP1R11,DUSP11,DDX5,WDR62,TAF6,ESPL1,PURA,DDB1,DEF6,IPO4,FAM83G,UBL3,NAT9,PIGM,LYRM4,GPR132,UBE2Q1,PTP4A3,BRIX1,MRPL19,ZNF696,SF3B2,PCYOX1L,CDC42,SYNM,GOT2,JAZF1,HADHB,RPF2,SLC35C2,CNNM3,CARM1,SRPK2,WDR41,LARS,ZCCHC10,CCDC138,LRBA,TMEM216,SUMF2,KMT2C,OGFR,PRPSAP1,ASF1B,RPL37,MAN2A2,EIF4ENIF1,NIP7,U2SURP,MIA2,ZNF268,VPS4A,ATP6V0E1,PPP1R2,PM20D2,XPNPEP3,RGS2,LYAR,FAM89B,TRAFD1,SUGP2,GBA,EIF2A,SYVN1,CCDC71L,DAPK3,ARHGAP15,MASTL,UAP1,NFIL3,FN3KRP,YWHAZ,CTSA,TMEM14A,TOB1,TSEN15,ADNP2,TCF12,PRKAB1,MDH2,SMARCA4,ORC1,RRN3,UBXN2A,IARS,CD3EAP,KIF14,EXOSC1,CS,CLTB,DNAL4,CSTF1,POU2AF1,UBQLN4,NXT1,HPDL,PGGT1B,SELPLG,SMU1,ATXN1,GLO1,OGDH,BICD2,CADM1,EDEM2,HERPUD2,TOLLIP,FANCE,MBD3,PDHX,RPS9,ALKBH6,SURF4,DUS3L,ARNTL,ANP32E,FKBP5,TMEM101,CCDC125,ABCA1,PDCD2L,GCLM,RAE1,DCTN2,NUP54,CHIC2,PAWR,MXD4,DCUN1D4,PIP4K2A,XPR1,FERMT3,KIF5B,KLHL20,SEC24C,RRBP1,ARHGEF2,ANP32A,LDLRAD3,STAT3,MYO5A,NIPAL3,AMPD2,TXNL1,PHF20L1,DCAF6,FAM49B,TMEM39A,ATP2C1,RFFL,COG1,RCOR1,PRMT2,TFEB,LEMD2,UPF1,ELMO1,ZC3H7B,DTX4,ZMIZ1,TERF1,HRAS,CCDC93,FGFR1OP,PIGQ,AGPAT1,CNTROB,PPP1R16B,MIS12,GSDMB,TTC9C,PDS5B,NUP153,SENP1,PGAP2,TMEM115,PLEKHM3,DCUN1D5,PLEKHF2,BRMS1,PWWP2B,TRIM47,WDR11,AXIN1,SMG9,TRIM52,LONP2,NDUFV2,PHF23,CERK,SLC4A2,EZH1,ITGB5,LMNA,MCTS1,DDX56,EIF2S2,SLC38A5,FOXN2,CARS2,PRRC2A,C16orf72,RB1CC1,ZMYND11,PGS1,MYBL2,UHRF1BP1,SRSF5,MPG,MATR3,CYB5A,NCDN,POLR2J,SETD3,TEX30,PTAR1,CNOT6,NDE1,EGLN1,ZNF207,ANKRD27,PPP1R37,ABCA3,SARNP,IVNS1ABP,MON1B,RMI2,TMEM97,NIT2,NUF2,ZNF267,TCF19,TMEM161B,KTN1,APP,PRKD3,CLUAP1,ATP2A2,UTP18,GRSF1,DUT,ZCCHC2,ANAPC7,RNF19A,FAM76B,CLN6,TMEM9,GCC1,RNF169,ADCY7,ATP6V1G1,ENPP4,RNPS1,CDCA2,FKBP3,GPR137,DDX17,CHCHD3,PEX5,CDC16,HIPK2,MBOAT1,TICAM1,PDXK,ZBTB11,ANXA6,TMBIM4,GMCL1,UBE4A,IL21R,ETS1,WRB,ZNF92,PNO1,CAPN2,ADD3,SUV39H2,TTLL12,TPCN1,HNRNPM,LYPLA2,MFSD12,LDHB,PPP3CA,NUDT8,POLK,JTB,EMP3,MTMR12,ZP3,PDE3B,KIF18A,CCDC6,WNT5B,MAPK6,LY75,C4orf46,SLC25A19,RGL1,PSAP,WDR76,IGBP1,FAF1,SNAPIN,COX15,AGRN,THOC1,GNPDA1,GPBP1L1,PPP1R15B,CSNK2A1,EBNA1BP2,GIT2,BIRC2,ATPAF1,DLG5,ABL2,XRCC2,ZFYVE27,MCMBP,PTPRK,CDC37,SP3,METTL1,HARS,GMFB,ESYT1,ANLN,RAB5B,RHEB,DPYSL3,TBC1D17,TIMM13,CDCA4,TONSL,NRM,NAGLU,ACTB,ZNF45,CTCF,ASAH1,DOCK11,CRLF3,ASXL2,LRRC14,NUS1,SLC27A4,AFF1,MDFIC,MAML1,CYTH1,NQO2,UTP15,EIF2AK1,EIF4G2,ZDHHC3,MOSPD3,ITPRIPL1,CDC27,SNAP23,TBPL1,PRMT7,KCTD7,NDUFA5,CYLD,UGP2,DYNLL1,COPE,ZADH2,GGPS1,RPAIN,RAD23A,PDK2,ATP6V0B,STRBP,DUS4L,MRPL34,PDCD2,SAP30L,CLPTM1,SLC39A9,RPL29,BTG2,DNAJC9,FRAT2,MTMR6,NFATC2,KDM1B,ARL5B,USP36,CCDC127,MRPL2,ATP1A1,CLK3,MAFK,PSMD3,NDUFA11,CEP55,ZNF436,DNAJC17,NCOA1,SLC25A39,ZC3HC1,ZNF146,ATXN7L2,CDC40,SMAP1,GOLIM4,RRP15,DAP,GNE,SMC6,ARFIP2,NKRF,CHAC2,BZW2,WRNIP1,TMA7,SS18L1,CENPM,PTGES3,CAMK2G,MLEC,ZNF202,PPWD1,FAM50B,RHOT2,NEU1,TPD52L2,GOLGA7,TWSG1,PGRMC1,GLG1,FAM126A,RPS6KC1,UBE2C,PPCS,NDUFB6,TMEM41B,ZDHHC8,PLXNA1,CCNB1,SLC20A1,COMMD6,ABHD14A,POLR3K,C14orf119,ASAP2,SNUPN,CNPY4,PLCL2,TFG,SEH1L,ATG9A,PBK,MKI67,DDX20,AMDHD2,SLC17A5,GALNT7,CCNF,FOXRED1,RBM47,PTER,WDR4,DHTKD1,TRAF5,HDAC2,PWWP2A,HSPH1,LIME1,MAPRE1,CHTF18,ADO,KIF23,SLC35B1,NOTCH2,PMF1,COPG2,JMY,FKBP1A,SLC31A1,SNX18,ATIC,CTPS1,ATP6V0A2,PIKFYVE,RNF135,LPCAT1,EEF1D,TMED2,PHF10,FTL,DDX28,ZNF84,SIGMAR1,PIP4K2C,FAM133B,RIT1,PLEC,KDM3A,SF3A2,FAS,EPRS,ZNF777,TMEM54,QARS,PPP3R1,TCOF1,NRBP1,CABLES1,DNMT3A,RWDD1,CKLF,TRIP10,SF3B1,RPS6KA1,CAST,SUZ12,RAC1,GPR89A,OLA1,GNB2,FLAD1,APLP2,KDM2A,TNPO2,CDKN1B,TALDO1,GPX4,ATP13A1,RFC3,MAPRE2,ERF,CUL3,SLBP,KIAA1586,H2AFV,POLG2,GAR1,PSMB9,DHX57,HSPA4,MRPL55,JAK1,TBL3,GOLGA8A,SEL1L,H2AFX,KLHDC4,B4GALT3,PDCD11,ATMIN,POLQ,POU3F2,OTUD5,NCOR2,ANKRD13D,PKP4,SCAMP3,BABAM1,CDCA3,SLC25A12,BLM,TMCC3,GTF2F1,RPL17,CRAT,AHSA1,PRC1,UPF2,COPS7B,SLC38A10,CNOT6L,CNPY3,UBE2M,IFT46,TMEM160,TSHZ1,ZFP64,DENND4C,DENND1B,WDR18,RPL8,ILF3,LRRC1,RHOT1,MARK2,TSR2,ECH1,PRDX1,PLD3,NUCB1,GNA12,FBXO21,C1orf131,PRDX3,PFDN4,HNRNPH3,STX18,TFDP1,KHSRP,ASNA1,CPEB2,SSSCA1,VPS29,BYSL,S100PBP,MIB2,IER2,PTMS,NOP2,UBN1,DCAF15,NF1,FLYWCH2,ALKBH5,MOGS,UBE2Z,TAF6L,MAPK14,BECN1,SNAPC4,RNF103,BCAT2,MBD4,C18orf32,METTL14,ZNHIT6,IMPAD1,RCSD1,PHTF1,SRI,KIF22,ZBTB22,NFU1,OGG1,TRIM14,ELOF1,COPS8,FYTTD1,TRIM8,RRM2,SOX4,ABHD5,CXXC4,UBTF,PAF1,UEVLD,SPATA2,PQBP1,IARS2,ATXN2L,GALNT10,STARD3NL,RPS15,PIGN,AGTRAP,CIB1,XPO7,SRRT,ZNF449,CAPZA1,GLTP,BCL2,KIFAP3,N4BP2,HP1BP3,VOPP1,THNSL1,ISG15,CAND1,C22orf46,GNAS,TSC1,RBM25,CDCA5,ZFP90,NANP,RBBP4,ZBTB24,SMARCD1,MBD1,WASF2,MMACHC,TOMM20,IFI27L1,GNPNAT1,MPHOSPH8,HNRNPUL2,CHD1,MEAF6,CCDC50,AKAP8,PARL,RPN2,CHTOP,FAM3A,F2R,TMEM14C,SCYL3,ABI1,HTRA2,MOSPD1,RLIM,FAM172A,ZNF500,PSMB7,NLN,WIPF1,BOLA1,BUD13,NDUFB1,PEF1,EIF3G,BTBD1,TAB2,CHCHD1,TULP3,WDR59,CANT1,SCARB1,GAS2,USP11,SMURF1,TSPAN5,PPP2R2D,CDS2,MAGEH1,MRPL42,EYA1,CDK2AP2,MRPS26,LETMD1,KLF13,HDDC2,RGS1,MAN1A1,FBXO5,GART,PELO,TANK,BRD7,MRPL11,SAMD4B,ZDHHC18,GTF3C6,POLR3GL,WDR81,MEN1,ZNF407,MFN2,COX8A,ZRANB2,SRSF3,MBD6,ATP6V1C1,IDH3B,TATDN1,TSC2,LACTB2,RBM4,ZNF275,ANKRD39,RPL23A,CDKN2C,NAPG,USF1,DNAAF2,MECR,AP1M1,UPRT,CRY2,ECD,RNF26,TIPARP,LRRC59,RHBDD2,MGAT5,BAK1,ZNF559,RHOBTB3,GABPA,WBP1,NUTF2,ARF4,GINS4,KRIT1,BOLA3,AHNAK,RAD18,PDRG1,RNASEL,CHPF2,PDCD4,SMNDC1,NXT2,HIVEP3,KIAA0100,CLSPN,RHOC,DHX9,PDCD7,PSMD9,HAUS2,COPB2,TFAP4,CD59,RNFT1,RIMS3,MEGF8,EFTUD2,FBXO7,CPSF4,MRPL21,PHKG2,LUC7L2,SRSF11,EIF3L,MTA2,TYW1,USP10,ITM2A,SSR2,BCLAF1,MTX1,SFXN5,FNTA,PDLIM1,TXNDC16,ZNF830,TMEM159,MRPL3,ALS2,FAM72A,TRIM41,KARS,NQO1,POC1A,ANK3,PTTG1,TPX2,TBC1D13,DAZAP2,GLRX3,STMN1,C19orf48,REPS1,CBWD5,ABHD16A,FBXL6,SH3BP1,MTA1,UBA5,CLCN6,INTS12,RPRD1B,CGGBP1,CPNE1,SEC61B,FAM118B,GOPC,E2F3,CIRBP,CRNKL1,PFKFB3,GORAB,RAB1A,GIGYF1,TMEM184C,PPP2CA,KIF2A,CCDC14,LSM6,RNF38,SNRPG,CENPBD1,DMWD,USP13,ZFP91,TRMT6,IP6K2,WDR5,SLC25A43,IFT27,PMVK,NEIL2,RRP36,SRXN1,RPA2,PSMD2,CLIC4,PDCD10,CBWD2,COQ4,ITGB8,ARF5,ARHGEF1,FBXL19,GTF2H2,TTPAL,UTP20,MAGT1,GPS2,DBI,SSNA1,CD81,TMEM131,WDR13,FANCI,PAPOLA,CREM,TET3,FANCL,GLIS2,IL6ST,INTS1,POP7,SLC44A1,MTPN,ASB6,PLK1,RPP25,SEPT9,CELSR2,RBX1,APH1A,RAD51AP1,ZBED5,CKAP2L,PSMG1,UBE2V1,IL12RB1,EAF2,KRTCAP2,LUC7L,LSG1,NECAP2,C1orf122,ALG3,TRIM4,AGPAT2,CHD3,ZNF367,E2F4,PRPF4,KPNA2,BEND6,CLN3,DNAJC30,FAM208A,NGLY1,POT1,MYL12B,CCDC137,RMND5A,HJURP,PHB2,FAM53C,DNAJB2,NKD2,SDC2,KLC1,CDK13,ADCK5,COX4I1,RAB6A,DNAJB1,ARID1B,C1GALT1,MLX,UBE2Q2,CCP110,ZNF746,ARL6IP1,CTR9,NIPSNAP1,ABHD2,DCAF8,ACSL3,LDB1,MAP4K3,ARMC8,RBM38,IRF5,NMT2,HAUS8,MBIP,ORMDL2,COX7A2L,ZDHHC7,FAM122A,SIL1,DTD1,UNC13C,BCCIP,SART1,TRAF7,TOR1AIP1,ZNF416,LAGE3,ZFYVE21,TM9SF3,RRAGC,ZNF121,OIP5,NRF1,WDR44,PIN1,PPME1,EFCAB11,RPAP1,CABLES2,TOP1MT,LMAN1,AHCYL1,STRAP,SPSB3,ZNF583,SNX25,ARHGAP17,POLR2G,ZNF780B,PPT1,NUP155,DCLRE1C,MRPS14,RHBDF2,SUGP1,RBL1,FASTK,UBXN2B,STK38,AP1S1,SPRYD4,SLC22A23,H3F3A,CHID1,SMAD4,RAD51D,SLC30A9,NADSYN1,UNK,CMAS,HMGN3,NCAPG,SCYL2,FZD6,HERC3,GTPBP3,CTSS,ORC3,RNLS,YTHDC1,ACP2,CSRP1,HMGN5,METTL5,ABCF2,TUFM,RANGAP1,PNPLA8,HAGH,API5,ZFR,SEC23IP,E2F1,USP20,TMEM219,RBPJ,MAX,PDCD6IP,GXYLT1,LUZP1,ADAM10,CXXC1,TSC22D3,AP3M2,CUL1,GYG1,NANS,OAT,MYEF2,ANKRD26,PA2G4,NOL11,FIZ1,ZNF200,MARCH2,SLC26A2,SRP72,KLF10,LACTB,RFC2,CBFB,RAB2B,PRIM1,MAP3K4,HHEX,RPS14,LUC7L3,MAP4,MRPL27,BTF3,PTPDC1,CCDC59,NMD3,PTOV1,COX5B,DNAJC5,SCOC,DHPS,POLR2K,ANKH,C16orf87,VAV2,PRKAA1,GSPT2,DLGAP4,TATDN3,PXMP2,PRPF39,PSEN1,ZNF79,PDXDC1,VPS25,NDUFS7,YY1AP1,C12orf10,FAM192A,RPN1,LHX8,ZNRF2,DAPK1,TPST1,CYC1,SOCS5,FDFT1,PIGT,WDR1,EMB,ZNF574,C1orf35,EXOSC9,ARID1A,PTTG1IP,C9orf40,FXR1,GOSR1,MAP2K2,TWISTNB,AKAP1,XRCC5,HMGN2,PI4K2A,CAT,DERL1,MTHFD2,HSPBP1,CEBPG,ARAP1,FAM83D,USP32,CABIN1,SMPD4,GPI,CYTIP,TP53RK,REPS2,RAB11B,UROD,SLC39A13,POMP,BCL2L1,NUDT19,DECR1,RALB,SIAH1,LPIN2,ADCY9,SOCS6,MRPS27,TTC3,RNASEH2A,CFL1,ANKLE2,CDC123,OAF,VDAC2,ERC1,EML4,AMZ2,ANKZF1,ZNF282,RAD51C,DSN1,DDOST,HINT1,DGCR8,SAFB,HAGHL,LMBR1,FTSJ1,RWDD4,NCLN,BEND3,EYA2,DYNC1LI2,B4GALT5,SLC41A1,MANBA,TKT,FAM76A,CBLL1,ARGLU1,LANCL1,POFUT1,FAM8A1,HEATR5B,HLA-A,EBP,RFWD3,FUT8,FJX1,BTF3L4,PTPN11,MRPL54,FEM1B,RPL19,CNN2,NDUFA3,MTX2,MSH6,PDLIM2,LONRF3,RFXANK,FBXO9,GUF1,RPL32,ZHX1,NDUFS5,WDR91,HIGD2A,GPR89B,RORB,POLA2,ZNF76,MTX3,COPA,HMGXB3,PHRF1,ABCB10,MAP1LC3B,DST,SIVA1,RAB35,GPATCH1,TCEA1,DRAM2,DEAF1,TRAPPC13,SNRNP200,NCK1,LAP3,VHL,SREK1,ARHGDIB,PITPNB,HSPB11,BRWD1,PPM1G,SH3GLB2,CRCP,BAZ1B,CAB39,ACBD4,STK11,CLU,CHEK2,ZSWIM3,TSTD2,MRPL13,CHPT1,DCAF5,CAPN1,UBE2D3,NSMCE4A,PPP1R12A,ZCCHC8,GORASP1,NACA,UBXN1,C19orf25,PCSK7,EPN1,RPL15,THRAP3,TTF1,QSOX2,NUP205,PRPF18,CHKA,DTL,MED10,ZRANB1,MCPH1,SLC12A2,ATP6V0D1,CSNK1G3,NUDT4,RPL6,VKORC1,SLTM,EVC2,KLHL15,SIAH2,SLC16A1,EHD4,SNRNP70,C11orf1,APOL2,N4BP2L2,SNX27,CHMP2A,CORO7,FEZ2,UCK2,PMS2,UCK1,CLCC1,EXT2,MXD1,USP5,HNRNPA2B1,SAP130,NVL,PPP6C,CYB5R1,ZNF770,EBAG9,RNF25,PCGF6,METTL2A,FAM72B,PON2,HNRNPR,HPS5,STAT6,MAPK1,BRD9,TMEM33,PDF,DNAJC2,TRIP12,SHPRH,SCYL1,VPS45,MYO9B,GFM2,SPPL2A,FASTKD3,FGFR3,MZT2A,PPIG,ZDHHC13,TMEM99,H2AFY,ATG13,NDUFS8,ERI3,FBL,SLC35A1,FRMD8,MICAL3,TGFB1,B3GALT6,ELOVL5,HEMK1,TIMMDC1,HELB,PSPC1,MIER1,SCFD2,NDRG3,ARL17A,CDK11A,MTMR3,MEGF9,ACAT1,CENPT,PLOD3,RAB3IL1,ZSWIM6,RAB14,ADD1,MRPS15,KDM4A,XIAP,DHX8,GLUD1,ANKRD23,PABPC4,CALM2,CDK5,PSMD1,NEK6,NSRP1,RABGAP1L,SRSF4,FNIP2,KCNAB2,PCBP2,MLST8,PLK3,ZNF672,MRPL43,HSDL1,TOPORS,MCL1,SMC2,PPFIA3,ICMT,SLC50A1,STOML2,LIMK1,ZNF689,PRDX5,ATE1,MLYCD,ATP6V0C,ST3GAL2,FBXL3,TFDP2,E2F2,PFKP,AAAS,DDX42,SSRP1,MRPL9,MRPS2,STRN4,TOP2B,ZNRF3,TMED3,DDRGK1,RAVER2,GNS,INTS7,INPP5A,MCM5,PHF14,ZNF326,UBE2QL1,NAGPA,TIMM8B,ETV3,TSPYL4,TSPAN31,DHX29,TEX10,MAN1B1,RPS10,CBFA2T2,ABCF1,RHOB,LRRC14B,DTWD1,PTPRF,SCARB2,OSBPL11,CCDC86,DUSP3,SLAIN1,MDH1,HEXA,RNF139,SNX14,ZNF296,TRERF1,UBR2,CHD1L,ACTR3,WDTC1,MYH9,CREBL2,NIPA2,PRKACA,SAFB2,ANKIB1,STAM,ARL6IP6,RAB21,SP100,ZKSCAN1,DDA1,NUP107,ANKRD13C,MAVS,CEP63,TMEM136,RBM15,ATF2,DCTN1,SHOC2,PSRC1,MAP4K4,WBP2,ATP6V0A1,NUSAP1,NDUFA7,DNAJA1,TAZ,C19orf54,TAF2,SEC61A1,WDR7,RPLP1,CBLN2,FUS,GEN1,LRP8,COIL,LRCH1,GALK1,ZNF786,RPS2,SESTD1,TRAK1,JMJD6,SIKE1,AKT1S1,KRI1,FBXO3,ERH,GATC,NDUFB4,PPP1R8,PRDM4,GTSE1,GEMIN6,DCP1A,SGCB,S100A6,IMPA2,PDPK1,TK1,GUK1,TNFAIP3,GALC,ZNF512,KIAA0930,MRPS10,DDX39A,RPA1,ZNF862,ZNF180,KEAP1,POLE,TATDN2,PITX1,CAPN7,LRPPRC,PML,HMGB2,USF2,ANAPC4,SRM,DDX47,MCCC1,S1PR2,CDIPT,SEC16A,SSR1,LIN9,PCNA,ZNF639,TRMU,PIK3R2,ETV6,TXLNA,PPCDC,FAM86C1,MYBL1,MRPL32,CCAR1,ABCC5,PBXIP1,BAZ2A,TLK1,MRPL12,EZR,LNX2,LRP5,BRCA1,PRKRA,STX16,EPB41,OPTN,SEPT1,SOCS4,QRSL1,PIEZO1,OSGEPL1,GLCCI1,NUDT11,NAA60,GEMIN7,SEPHS2,LZTR1,RACGAP1,PPP3CB,B4GALT4,RLF,RAPGEF6,SNRNP25,RB1,VASP,MED8,VMP1,PPIL2,MEA1,TIMELESS,AHDC1,ALDH18A1,TMEM8A,ABCC1,PREB,TRAPPC9,AACS,MEMO1,KRAS,RTF1,UBE4B,NFATC2IP,ARPC1A,ZNF174,PSMC4,GOLGA4,PALB2,SYNCRIP,PRPS2,NIPA1,TIGD2,RNF114,FOXM1,MRPL39,XAB2,SUMO2,DUSP22,COMMD8,RPL11,CSDE1,MDM2,CORO1A,MINPP1,METTL9,POC5,DVL2,GM2A,PSMA8,COQ10B,CPOX,TIGD5,SLC26A6,CYP20A1,PRPF3,TXNL4A,RPSA,SRSF1,DNAJC10,SCAP,ZNF700,PLEKHG4B,TIMM17A,TOMM6,FAU,LTA4H,AP2S1,USP53,INTS2,CTDP1,MIF4GD,CDT1,ARID5A,SUMF1,GGA2,AP3S1,CSNK1A1,RMI1,TFRC,PTPN2,IRF4,GSTK1,NDUFV1,SLC1A4,CWC27,SLC35B4,DDX31,ABCD1,RPAP3,CNTN5,SNX2,ZMYM5,CCDC34,CHCHD6,BSDC1,KPNA4,CDKN2AIPNL,FBXO41,BIRC5,TFE3,SNAP29,CDCA7L,PKD2,ACADM,CHMP7,GCSH,ZNF496,TMEM109,TAP1,YTHDF3,NHLRC3,IKBIP,EIF1B,ELMOD2,KIFC1,DBNDD1,CYB5RL,PARPBP,RNASEK,CDC25B,PRADC1,DNMT1,NOL12,ORAI2,USO1,AKT2,NOL8,GNG7,AURKB,MCFD2,SLC25A5,ZFAND5,MAK16,STT3A,TMED10,PSMD8,EIF2D,ITGB1,PTPN7,UQCRH,RRS1,ARRB2,RTN3,ZNF598,SVIP,DDX58,WSB2,PPIB,MUT,GMFG,HLA-E,NDUFA4,MAN2B1,METTL3,CFLAR,NDUFS4,RNF121,MEX3C,KLF16,HDAC7,BDH1,PCYT2,GNAI2,ANKHD1,TERF2,MORC3,KCTD20,SEPT8,DCTD,PKM,TOMM40,PATL1,ADSS,SERTAD2,SERF2,ZFP92,NSF,DCK,ERGIC3,ACLY,LPCAT4,VCPIP1,YY1,PPP6R3,PPP6R2,MAP3K5,RNF14,CDK2,ZC3HAV1,SYS1,ZBTB37,URB2,EIF3D,MAGED1,KLHL18,ADPGK,SLC25A44,AP1B1,SDHA,PAIP2,PHC2,CRKL,TERF2IP,MOAP1,CYHR1,ZNF75D,SHC1,UCHL5,NAA35,TMBIM1,CCT2,CDKN2AIP,MKLN1,HMGN4,LYRM1,GALK2,CDC23,SHCBP1,AP4E1,PRDM11,VEZF1,PPP2R5A,ACYP1,STAT1,PPA2,TRIM32,RHEBL1,R3HCC1L,C1orf112,MRI1,TCF3,BRAP,AGPAT3,MYNN,SDF2L1,SPR,RAB11A,REEP5,FOXO3,MAD2L2,CCDC28A,PIP5K1C,RBM17,MAT2B,PTEN,CENPJ,TAGLN2,OSTC,CREB1,PACS2,NCOA2,SMC4,NEK7,NET1,PARP4,TBRG4,ANAPC2,YIF1A,SGSH,HGS,TTLL4,SLC38A7,MFAP1,CCDC69,BRWD3,ESYT2,SKA3,NPHP4,UBE2E2,HNRNPAB,PLXNC1,TMEM184B,ST13,DNAJC24,ZNF107,KIF2C,SLC29A1,AGFG1,SIRT2,FKBP2,USP48,UBQLN2,SNRPD3,CUTC,EDC3,UBLCP1,ZNF804A,RAP1A,THADA,EIF4A3,AP3S2,ATG3,DPYSL2,PPP1R12C,AKR1B1,NDUFB9,JOSD1,RP2,TTC4,TECR,ARID4A,FGFR1OP2,TIMM50,TDP1,DPM1,FOPNL,SLC16A7,WDR82,SLC25A22,STK17B,DHX15,CHAF1A,GEMIN5,COPS6,SASS6,RPS26,PSMC1,SLC12A7,TBC1D12,TM9SF4,ZNF768,UFC1,MED13L,TIA1,MEF2A,EPHX2,PITHD1,RHBDD1,NFATC3,BUD31,ZNF335,YBX1,KNTC1,ACAD8,UBE3C,ZNF189,ALDH9A1,KDELR1,TSTA3,CIC,OXR1,SEPT7,NAP1L1,NSMF,ODF2,EXOC4,KIAA1328,NUP62,PITPNA,NAA20,PTDSS1,MZT2B,PDSS2,C7orf26,TMEM106C,IMMT,ASH1L,CHERP,WDYHV1,PLAGL2,CHKB,IRF3,TWF2,PAIP1,ANKRD28,ANKLE1,FARSA,SAR1A,SCAMP4,APOOL,PDIA6,ACSL5,TOR1AIP2,AZI2,GFER,RAD54B,DAP3,TMEM41A,ZNF317,GADD45B,AKNA,REEP4,CBX4,KIF3B,GOLPH3L,SH2D3A,CASP6,TOR3A,SRGN,DBF4,MFSD10,SAC3D1,CTNNBL1,YIF1B,CLDND1,TTC17,GINS1,PAQR6,CSNK1G2,TELO2,ADAM17,HMGN1,NASP,ASPM,PPP1R21,PRKAR1B,SYMPK,TARS,SNRPA,MAPK3,HSPA1B,HLA-B,ATAD2,PLAA,ZNF330,OSBPL8,KBTBD7,PREPL |
| 1.726e-02 | -4.06 | UBXN8 (UBX domain protein 8) | protein interactions | 7993 | 26 | 9 | 17029 | 2761 |
VCPIP1,TBC1D17,SYVN1,ADRB2,SURF4,TMEM165,RHBDD2,NPLOC4,MSH2 |
| 1.726e-02 | -4.06 | SPINK2 (serine peptidase inhibitor, Kazal type 2) | protein interactions | 6691 | 26 | 9 | 17029 | 2761 |
MOB4,NUDT8,ATP6V1D,IDE,IKBIP,DCAF15,STRIP1,UBR2,STRN4 |
| 1.726e-02 | -4.06 | KDM4A (lysine demethylase 4A) | protein interactions | 9682 | 26 | 9 | 17029 | 2761 |
RB1,WAS,KDM4A,CAPZA1,CUL1,STK11,H3F3A,WDR48,ABHD5 |
| 1.726e-02 | -4.06 | TLN2 (talin 2) | protein interactions | 83660 | 26 | 9 | 17029 | 2761 |
SYNCRIP,DGCR8,TRMT6,CHMP4B,DCUN1D5,TTC4,TWF2,CDC5L,PIP5K1C |
| 1.726e-02 | -4.06 | Smc1a (structural maintenance of chromosomes 1A) | protein interactions | 24061 | 26 | 9 | 17029 | 2761 |
GNAS,SMC3,MRPL27,ABCF2,CDCA5,MRPS27,PDS5B,PDF,USP13 |
| 1.726e-02 | -4.06 | CNKSR1 (connector enhancer of kinase suppressor of Ras 1) | protein interactions | 10256 | 26 | 9 | 17029 | 2761 |
CYTH1,RHOA,ASPM,PIN1,RAF1,ARHGEF1,BRAP,SMAD4,MAP2K2 |
| 1.726e-02 | -4.06 | OTUD6B (OTU domain containing 6B) | protein interactions | 51633 | 26 | 9 | 17029 | 2761 |
GALC,CHD3,SEC24C,RPF2,MYH9,SMURF1,BTBD1,HDDC2,MCTS1 |
| 1.726e-02 | -4.06 | MINK1 (misshapen like kinase 1) | protein interactions | 50488 | 26 | 9 | 17029 | 2761 |
KIFAP3,YWHAZ,PKP4,NOP2,NCK1,ABI1,TSEN15,MAP4K4,PTPRK |
| 1.726e-02 | -4.06 | FEZ2 (fasciculation and elongation protein zeta 2) | protein interactions | 9637 | 26 | 9 | 17029 | 2761 |
TEDC2,NEK1,SMC3,SCOC,DRAP1,KPNA2,KRAS,PDCD7,SAP30L |
| 1.726e-02 | -4.06 | ANKRD11 (ankyrin repeat domain 11) | protein interactions | 29123 | 26 | 9 | 17029 | 2761 |
SYNCRIP,GOLGA2,GPS2,CDCA7L,PTAR1,RACGAP1,NCOA1,ARRB2,NCOA2 |
| 1.726e-02 | -4.06 | SLTM (SAFB like transcription modulator) | protein interactions | 79811 | 26 | 9 | 17029 | 2761 |
SUZ12,PLEC,SNRNP70,GGPS1,MATR3,ZC3HAV1,SSSCA1,SRPK2,TERF2 |
| 1.726e-02 | -4.06 | Fbxo21 (F-box protein 21) | protein interactions | 231670 | 26 | 9 | 17029 | 2761 |
CUL1,RPS2,PDCD7,RPL17,RPS14,ZNF800,FTSJ3,PHF14,ESYT2 |
| 1.726e-02 | -4.06 | QDPR (quinoid dihydropteridine reductase) | protein interactions | 5860 | 26 | 9 | 17029 | 2761 |
GART,PDCD6,RAE1,CUL3,CUL1,GLO1,KRAS,SPR,CAND1 |
| 1.726e-02 | -4.06 | FASTKD2 (FAST kinase domains 2) | protein interactions | 22868 | 26 | 9 | 17029 | 2761 |
MRPL50,USP7,DDX28,RBM42,RBMX,MRPL12,MCM2,ZC3H3,RCC1L |
| 1.727e-02 | -4.06 | GO_CELLULAR_MONOVALENT_INORGANIC_CATION_HOMEOSTASIS | MSigDB lists | GO_CELLULAR_MONOVALENT_INORGANIC_CATION_HOMEOSTASIS | 92 | 22 | 17377 | 2626 |
CLCN3,PPT1,RAB7A,SLC26A6,ATP6V0A1,SLC4A2,ATP6V1B2,TMEM165,ATP6V0B,ATP6V1D,ATP1A1,CLIC4,ATP6V0A2,ATP6V0C,BCL2,SLC26A2,ATP6V1C1,CLN3,CLN6,ATP6V0D1,ATP6V0E1,ATP6V1G1 |
| 1.727e-02 | -4.06 | thyroid-adenoma-nodule-goitre | COSMIC cancer mutations | thyroid-adenoma-nodule-goitre | 57 | 15 | 17385 | 2587 |
GNAS,FGFR3,RB1,NRAS,CCDC6,PTEN,VHL,PTPN11,STK11,KRAS,MEN1,TFG,SMAD4,HRAS,CDKN2A |
| 1.728e-02 | -4.06 | UBA | smart domains | SM00165 | 29 | 9 | 9493 | 1367 |
UBQLN4,HUWE1,UBXN1,RAD23B,UBQLN2,MARK2,USP13,RAD23A,USP5 |
| 1.730e-02 | -4.06 | positive regulation of telomere maintenance | biological process | GO:0032206 | 51 | 14 | 17256 | 2622 |
HNRNPA2B1,MAP3K4,CCT2,ERCC1,NEK7,NABP2,PML,AURKB,MAPK1,PARN,POT1,CCT8,MAPK3,XRCC5 |
| 1.732e-02 | -4.06 | DNM2 (dynamin 2) | protein interactions | 1785 | 121 | 29 | 17029 | 2761 |
PLK1,PPIB,EIF3L,FGFR1OP,STAU1,RPS2,ATXN3,NCK1,TRIP10,GGA1,DYNLL1,MAN1B1,APP,PICALM,SH3GLB1,CRKL,VAV1,SHC1,SNX18,PML,RTCB,PTPN11,RBMS1,RBM3,RUVBL2,WIPI2,ABI1,DCTN1,CDC5L |
| 1.732e-02 | -4.06 | GPATCH1 (G-patch domain containing 1) | protein interactions | 55094 | 48 | 14 | 17029 | 2761 |
FGFR1OP,CEP104,PCM1,CENPJ,ODF2,PPIE,YJU2,SNRPG,SASS6,NKAPD1,APP,LMNA,DCTN1,PRPF19 |
| 1.732e-02 | -4.06 | AHR (aryl hydrocarbon receptor) | protein interactions | 196 | 48 | 14 | 17029 | 2761 |
RB1,NCOR2,DAP3,IVNS1ABP,ARNTL,SMARCA4,PTGES3,NCOA1,BRCA1,TAF6,SMAD4,NCOA2,DDB1,GTF2F1 |
| 1.732e-02 | -4.06 | RNF5 (ring finger protein 5) | protein interactions | 6048 | 48 | 14 | 17029 | 2761 |
UBE2D3,DERL1,UBE2E2,TNFAIP3,SLC38A7,UBE2Z,XRCC3,UBE2V1,MAVS,ADRB2,TOMM40,BCAP31,RNF5,ABHD16A |
| 1.732e-02 | -4.06 | TIRAP (TIR domain containing adaptor protein) | protein interactions | 114609 | 48 | 14 | 17029 | 2761 |
PCNA,SNRNP200,JAK1,KAT2A,DHPS,TAB2,NF1,UBR2,LTN1,TICAM1,PRKRA,STAT3,APP,CAMK2G |
| 1.732e-02 | -4.06 | CCAR1 (cell division cycle and apoptosis regulator 1) | protein interactions | 55749 | 48 | 14 | 17029 | 2761 |
MDM2,PCNA,GOLGA2,CHERP,DCTN2,XRCC3,PCGF1,CCNB1,SAFB2,SMURF1,SF3A2,DCTN1,CAND1,PRIM1 |
| 1.732e-02 | -4.06 | GATAD2A (GATA zinc finger domain containing 2A) | protein interactions | 54815 | 48 | 14 | 17029 | 2761 |
PHF20L1,KPNA1,CHD3,MTA1,MTA2,MBD2,NABP2,KRAS,NFATC2,RBPJ,RBBP4,MBD3,HMG20A,HDAC2 |
| 1.732e-02 | -4.06 | ORC4 (origin recognition complex subunit 4) | protein interactions | 5000 | 48 | 14 | 17029 | 2761 |
MTMR3,RPA2,MCM10,KPNA1,DBF4,CAPZA2,ORC1,ORC3,MCM2,APP,PABPC1,CDKN2A,XRCC5,CDC5L |
| 1.732e-02 | -4.06 | LNX2 (ligand of numb-protein X 2) | protein interactions | 222484 | 48 | 14 | 17029 | 2761 |
RBM17,SRSF11,DDA1,LNX2,UBE2Z,ATP5F1B,IP6K2,UBE2I,NMD3,CBX4,TUBB,NUMB,OPTN,RLIM |
| 1.736e-02 | -4.05 | GO_PRENYLTRANSFERASE_ACTIVITY | MSigDB lists | GO_PRENYLTRANSFERASE_ACTIVITY | 15 | 6 | 17377 | 2626 |
FNTA,NUS1,GGPS1,PGGT1B,FDFT1,PTAR1 |
| 1.736e-02 | -4.05 | GO_DNA_N_GLYCOSYLASE_ACTIVITY | MSigDB lists | GO_DNA_N_GLYCOSYLASE_ACTIVITY | 15 | 6 | 17377 | 2626 |
PCNA,MPG,OGG1,NEIL3,NEIL2,MBD4 |
| 1.736e-02 | -4.05 | PID_ARF6_DOWNSTREAM_PATHWAY | MSigDB lists | PID_ARF6_DOWNSTREAM_PATHWAY | 15 | 6 | 17377 | 2626 |
RHOA,ARF1,MAPK1,RAB11A,RAC1,MAPK3 |
| 1.736e-02 | -4.05 | RICKMAN_TUMOR_DIFFERENTIATED_MODERATELY_VS_POORLY_DN | MSigDB lists | RICKMAN_TUMOR_DIFFERENTIATED_MODERATELY_VS_POORLY_DN | 15 | 6 | 17377 | 2626 |
ANP32A,SRSF3,LUC7L3,SRRT,CENPF,SRSF1 |
| 1.736e-02 | -4.05 | GO_EUKARYOTIC_TRANSLATION_INITIATION_FACTOR_3_COMPLEX | MSigDB lists | GO_EUKARYOTIC_TRANSLATION_INITIATION_FACTOR_3_COMPLEX | 15 | 6 | 17377 | 2626 |
EIF3K,EIF3L,EIF3G,EIF3D,EIF3A,EIF3H |
| 1.736e-02 | -4.05 | FINETTI_BREAST_CANCERS_KINOME_GRAY | MSigDB lists | FINETTI_BREAST_CANCERS_KINOME_GRAY | 15 | 6 | 17377 | 2626 |
MAP4K3,CSNK1A1,SCYL2,TLK1,CSNK1G3,PRPF4B |
| 1.736e-02 | -4.05 | REACTOME_PROCESSIVE_SYNTHESIS_ON_THE_LAGGING_STRAND | MSigDB lists | REACTOME_PROCESSIVE_SYNTHESIS_ON_THE_LAGGING_STRAND | 15 | 6 | 17377 | 2626 |
POLA2,RPA2,PCNA,PRIM2,RPA1,PRIM1 |
| 1.736e-02 | -4.05 | GO_SWI_SNF_COMPLEX | MSigDB lists | GO_SWI_SNF_COMPLEX | 15 | 6 | 17377 | 2626 |
SMARCA4,RB1,ARID1A,SMARCE1,ARID1B,SMARCD1 |
| 1.736e-02 | -4.05 | MARKS_HDAC_TARGETS_DN | MSigDB lists | MARKS_HDAC_TARGETS_DN | 15 | 6 | 17377 | 2626 |
BCL2,CCNA2,BCL2L1,BIRC5,CFLAR,XIAP |
| 1.736e-02 | -4.05 | BIOCARTA_BARRESTIN_SRC_PATHWAY | MSigDB lists | BIOCARTA_BARRESTIN_SRC_PATHWAY | 15 | 6 | 17377 | 2626 |
GNAS,MAPK1,MAP2K2,HRAS,RAF1,MAPK3 |
| 1.736e-02 | -4.05 | BARRIER_CANCER_RELAPSE_TUMOR_SAMPLE_UP | MSigDB lists | BARRIER_CANCER_RELAPSE_TUMOR_SAMPLE_UP | 15 | 6 | 17377 | 2626 |
PDCD10,H2AFZ,LYN,ATP6V0E1,DNAJB9,ATP6V1G1 |
| 1.736e-02 | -4.05 | LIU_IL13_PRIMING_MODEL | MSigDB lists | LIU_IL13_PRIMING_MODEL | 15 | 6 | 17377 | 2626 |
PLK3,GPATCH1,EMP3,JMJD6,CHMP4A,RAB5B |
| 1.736e-02 | -4.05 | REACTOME_CYCLIN_A_B1_ASSOCIATED_EVENTS_DURING_G2_M_TRANSITION | MSigDB lists | REACTOME_CYCLIN_A_B1_ASSOCIATED_EVENTS_DURING_G2_M_TRANSITION | 15 | 6 | 17377 | 2626 |
PLK1,CDC25B,PKMYT1,CCNA2,CCNB1,CCNB2 |
| 1.736e-02 | -4.05 | GO_MISFOLDED_OR_INCOMPLETELY_SYNTHESIZED_PROTEIN_CATABOLIC_PROCESS | MSigDB lists | GO_MISFOLDED_OR_INCOMPLETELY_SYNTHESIZED_PROTEIN_CATABOLIC_PROCESS | 15 | 6 | 17377 | 2626 |
ANKZF1,DERL1,SDF2L1,ATXN3,LONP2,RNF5 |
| 1.736e-02 | -4.05 | GO_PORE_COMPLEX_ASSEMBLY | MSigDB lists | GO_PORE_COMPLEX_ASSEMBLY | 15 | 6 | 17377 | 2626 |
NUP153,AHCTF1,CCT8,NUP205,NUP107,TMEM33 |
| 1.736e-02 | -4.05 | MARIADASON_RESPONSE_TO_CURCUMIN_SULINDAC_7 | MSigDB lists | MARIADASON_RESPONSE_TO_CURCUMIN_SULINDAC_7 | 15 | 6 | 17377 | 2626 |
ARHGEF2,NCKAP1,PCBP1,PPP1R8,KAT7,DRAM2 |
| 1.737e-02 | -4.05 | RAB | prosite domains | PS51419 | 72 | 17 | 12060 | 1670 |
RAB14,RAB11B,RAB7A,RAB23,RAB6A,RAB1A,IFT27,RAB5B,RAB11A,RAB22A,RAB2B,RAB21,RAB8A,RAB18,RAB24,RAB35,RAB4A |
| 1.740e-02 | -4.05 | GSE16450_CTRL_VS_IFNA_12H_STIM_IMMATURE_NEURON_CELL_LINE_UP | MSigDB lists | GSE16450_CTRL_VS_IFNA_12H_STIM_IMMATURE_NEURON_CELL_LINE_UP | 168 | 36 | 17377 | 2626 |
UBL3,USP7,PRPF38B,TRERF1,FAM172A,THOC1,KDM4A,NF1,URB2,LRBA,SCFD2,CIRBP,GTPBP4,MED13L,SND1,BLM,ZNF407,SLC20A1,PARN,QSOX2,XPR1,ARHGAP15,WWP2,ABL2,THADA,ZNF689,HNRNPH3,FUT8,GMEB1,SLC35B4,DTD1,DNAJC30,GPD1L,PDSS2,VPS13B,ADNP2 |
| 1.741e-02 | -4.05 | EIF4G3 (eukaryotic translation initiation factor 4 gamma 3) | protein interactions | 8672 | 39 | 12 | 17029 | 2761 |
MKNK1,WDYHV1,VAV2,USP10,CTR9,TARDBP,NFATC2IP,EIF4G2,PABPC1,SF3A2,PABPC4,EIF3H |
| 1.741e-02 | -4.05 | CNOT11 (CCR4-NOT transcription complex subunit 11) | protein interactions | 55571 | 39 | 12 | 17029 | 2761 |
CNOT9,GGNBP2,GPBP1L1,GADD45B,MAP4K4,CNOT6,CAPZA2,CNTROB,CNOT6L,EDRF1,TOB1,CNOT3 |
| 1.741e-02 | -4.05 | LRRTM1 (leucine rich repeat transmembrane neuronal 1) | protein interactions | 347730 | 39 | 12 | 17029 | 2761 |
NDC1,ATP13A1,NUS1,TMEM39A,TYW1,UPK3BL1,CISD2,UBE4A,TTC17,CNPY3,PDE3B,TMEM131 |
| 1.741e-02 | -4.05 | RNH1 (ribonuclease/angiogenin inhibitor 1) | protein interactions | 6050 | 39 | 12 | 17029 | 2761 |
ADSS,PSMD2,TNFAIP3,MAP4K4,ERO1A,PRPF4,PRPF3,PTGES3,UBQLN2,MCM2,CDC73,PRDX1 |
| 1.741e-02 | -4.05 | GMPPB (GDP-mannose pyrophosphorylase B) | protein interactions | 29925 | 39 | 12 | 17029 | 2761 |
CSDE1,WDR1,EIF2D,WDR82,KRAS,MTMR12,UBE2V1,ATP6V1B2,CCNB2,EYA2,LMNA,GLOD4 |
| 1.741e-02 | -4.05 | AKAP8L (A-kinase anchoring protein 8 like) | protein interactions | 26993 | 39 | 12 | 17029 | 2761 |
ANKRD28,SUZ12,MAGED1,ZNF746,DHX9,CUL3,CUL1,CDC6,PRKACA,SEC16A,MATR3,CAND1 |
| 1.741e-02 | -4.05 | NDC1 (NDC1 transmembrane nucleoporin) | protein interactions | 55706 | 39 | 12 | 17029 | 2761 |
ERGIC3,NUP107,TMEM216,KRAS,NUP153,BRCA1,UBE2I,TSPAN5,NUP58,IFI16,SEH1L,EVC2 |
| 1.741e-02 | -4.05 | NDUFAF8 (NADH:ubiquinone oxidoreductase complex assembly factor 8) | protein interactions | 284184 | 39 | 12 | 17029 | 2761 |
HNRNPA2B1,SPINDOC,NDUFA5,RPL6,STARD7,SLC16A1,CHCHD2,MRPL54,TUBB,ECH1,TIMM50,STOML2 |
| 1.741e-02 | -4.05 | SRI (sorcin) | protein interactions | 6717 | 39 | 12 | 17029 | 2761 |
TCF12,PDCD6IP,ATXN3,SMAD2,NRAS,TKT,SRI,SSNA1,STAT3,HAUS2,ANXA11,SRPK2 |
| 1.741e-02 | -4.05 | ACTR5 (ARP5 actin related protein 5 homolog) | protein interactions | 79913 | 39 | 12 | 17029 | 2761 |
TOMM20,INTS7,UCHL5,NARF,BCL7C,KNTC1,INO80E,RUVBL2,YY1,BLM,DDB1,PDF |
| 1.741e-02 | -4.05 | SETX (senataxin) | protein interactions | 23064 | 39 | 12 | 17029 | 2761 |
CYLD,POLR2G,PTEN,SUMO2,MEF2A,BRCA1,CNTROB,CLU,UBE2I,POLR2A,CDC5L,MLST8 |
| 1.741e-02 | -4.05 | USP36 (ubiquitin specific peptidase 36) | protein interactions | 57602 | 39 | 12 | 17029 | 2761 |
TRIM26,CELSR2,UTP18,SHPRH,TBL3,PPM1G,KIAA0232,PPP6R3,NUP85,IFI16,FANCI,SRPK2 |
| 1.741e-02 | -4.05 | hydrolase activity, hydrolyzing N-glycosyl compounds | molecular function | GO:0016799 | 23 | 8 | 17224 | 2647 |
MAN2A2,DNPH1,PCNA,MPG,OGG1,NEIL3,NEIL2,MBD4 |
| 1.741e-02 | -4.05 | chromatin disassembly | biological process | GO:0031498 | 19 | 7 | 17256 | 2622 |
SMARCA4,ARID1A,PBRM1,SMARCE1,ARID2,SUPT16H,SMARCD1 |
| 1.741e-02 | -4.05 | T cell lineage commitment | biological process | GO:0002360 | 19 | 7 | 17256 | 2622 |
BCL2,IRF4,CYLD,RHOA,STAT3,STAT6,PRKDC |
| 1.741e-02 | -4.05 | nucleosome disassembly | biological process | GO:0006337 | 19 | 7 | 17256 | 2622 |
SMARCA4,ARID1A,PBRM1,SMARCE1,ARID2,SUPT16H,SMARCD1 |
| 1.741e-02 | -4.05 | error-free translesion synthesis | biological process | GO:0070987 | 19 | 7 | 17256 | 2622 |
RPA2,RFC3,PCNA,RFC2,RPS27A,NPLOC4,RPA1 |
| 1.744e-02 | -4.05 | GSE22886_NAIVE_TCELL_VS_DC_DN | MSigDB lists | GSE22886_NAIVE_TCELL_VS_DC_DN | 196 | 41 | 17377 | 2626 |
TBC1D12,NDUFV2,FEZ2,NQO1,RAC1,SDC2,ZFYVE21,MAN2B1,ZNF267,ZNF804A,CDK5,ATP6V0B,PSMD1,ARPC5,DAPK1,H2AFY,TFG,TALDO1,PPIF,FTL,ADAM17,PPT1,CREG1,RAB7A,KIAA0930,RCOR1,RIT1,VDAC1,NEU1,PRDX1,MFN2,PI4K2A,HSPA4,MTHFD2,RBM47,CORO1C,MPV17,COX8A,MDH1,ZMIZ1,EHD4 |
| 1.745e-02 | -4.05 | promoter-specific chromatin binding | molecular function | GO:1990841 | 41 | 12 | 17224 | 2647 |
RBL1,WDR13,SUZ12,E2F4,DHX9,STAT1,DDX5,DNMT1,TRIM28,HDAC2,POLR2A,GTF2F1 |
| 1.745e-02 | -4.05 | cis-trans isomerase activity | molecular function | GO:0016859 | 41 | 12 | 17224 | 2647 |
FKBP1A,PPIF,PPIB,CWC27,PPIG,PIN1,PPIL2,PPIE,FKBP5,PPWD1,FKBP2,FKBP3 |
| 1.745e-02 | -4.05 | MAP3K7 (mitogen-activated protein kinase kinase kinase 7) | protein interactions | 6885 | 157 | 36 | 17029 | 2761 |
MIB2,PRKAB1,CYLD,MAGED1,PRKAA1,XIAP,DAZAP2,MAPK14,SIVA1,ZNF746,PPP6C,MAVS,RNF19A,MAP3K14,STAT3,CDC37,PDPK1,TRIM8,KAT2A,RBX1,TAOK1,MAP4K4,PRMT2,MCM2,ERC1,HGS,HSPBP1,TAB2,HIPK2,E2F4,MAPK6,MAP3K5,PPP5C,TRAF5,ARRB2,SGF29 |
| 1.749e-02 | -4.05 | GSE10211_UV_INACT_SENDAI_VS_LIVE_SENDAI_VIRUS_TRACHEAL_EPITHELIAL_CELLS_UP | MSigDB lists | GSE10211_UV_INACT_SENDAI_VS_LIVE_SENDAI_VIRUS_TRACHEAL_EPITHELIAL_CELLS_UP | 135 | 30 | 17377 | 2626 |
ORAI2,PHF20L1,GPR132,EMB,TBRG4,KLHL18,AKT1S1,MACF1,SNAPC4,MTR,RAVER2,JAKMIP1,TSC1,GALNT2,JAK1,PDLIM1,KLHL5,ACYP1,CENPJ,LUC7L3,PIAS2,LMBR1,ZFYVE27,FAM122A,MBOAT1,NANP,ARRB2,USP53,SMAD4,NUMB |
| 1.749e-02 | -4.05 | GSE21033_CTRL_VS_POLYIC_STIM_DC_24H_DN | MSigDB lists | GSE21033_CTRL_VS_POLYIC_STIM_DC_24H_DN | 135 | 30 | 17377 | 2626 |
NOL12,GCLM,RHOA,ERMP1,MUM1,POMP,TWF2,SLC25A5,RFC2,MRPS14,GAR1,APP,PSMB3,WRNIP1,LYAR,GSTK1,SNRNP25,SLC19A1,TONSL,RNASEK,MRPL27,WDR4,MAVS,RNASEH2A,NFU1,KCNAB2,HIGD2A,GPATCH4,ELOF1,STARD3NL |
| 1.749e-02 | -4.05 | MODULE_192 | MSigDB lists | MODULE_192 | 108 | 25 | 17377 | 2626 |
CYTH1,GCLM,LZTR1,SNX2,ACSL3,PFKFB3,DNAJC9,CCNB1,PSEN1,MIEN1,MAD2L2,HSPA1B,MCTS1,DDX17,GTPBP3,NUP210,RPL32,ARPC5,ATE1,PPP1R11,SIL1,AP1S1,GAS2,ESYT2,GEMIN7 |
| 1.749e-02 | -4.05 | SIGLECL1 (SIGLEC family like 1) | protein interactions | 284369 | 96 | 24 | 17029 | 2761 |
NOP9,TSC2,DEPDC1,NF1,PPP1R15B,BTAF1,DDX20,SLC29A1,UBE4A,AP1B1,SYMPK,CIP2A,MAP3K4,THADA,KIF14,NUP107,LTN1,TNPO3,TNPO2,GEMIN6,KNTC1,GEMIN4,SNX14,IPO4 |
| 1.749e-02 | -4.05 | endosome organization | biological process | GO:0007032 | 71 | 18 | 17256 | 2622 |
CHMP2A,CLCN3,PDCD6IP,CHMP2B,RAB5B,RAB11A,STAM,VPS25,RAB22A,PI4K2A,TMEM127,HGS,CHMP4A,CHMP4B,VPS4A,RNF26,CHMP7,ALS2 |
| 1.753e-02 | -4.04 | GSE7768_OVA_ALONE_VS_OVA_WITH_LPS_IMMUNIZED_MOUSE_WHOLE_SPLEEN_6H_UP | MSigDB lists | GSE7768_OVA_ALONE_VS_OVA_WITH_LPS_IMMUNIZED_MOUSE_WHOLE_SPLEEN_6H_UP | 157 | 34 | 17377 | 2626 |
MUM1,NIT2,LACTB2,COMMD5,PDCD7,ELMOD2,STARD9,ZBTB45,TBC1D14,PPCDC,SOCS6,CDC25B,SLC35A1,SNX8,PLK3,PDPK1,GCC2,SNX2,TMEM126B,TUBGCP5,SLBP,SEPT7,PRKRA,POLG2,MYO1F,MTMR3,FBXO21,OSBPL11,KBTBD7,MPV17,BAZ1B,NCOA1,DEF6,TIGD2 |
| 1.754e-02 | -4.04 | RNA polymerase I activity | molecular function | GO:0001054 | 11 | 5 | 17224 | 2647 |
POLR1B,POLR2L,POLR2K,ZNRD1,TWISTNB |
| 1.754e-02 | -4.04 | 5S rRNA binding | molecular function | GO:0008097 | 11 | 5 | 17224 | 2647 |
RPF2,GTF3A,MDM2,RRS1,RPL11 |
| 1.754e-02 | -4.04 | oxidized DNA binding | molecular function | GO:0032356 | 11 | 5 | 17224 | 2647 |
BLM,POT1,OGG1,MSH6,MSH2 |
| 1.754e-02 | -4.04 | siRNA binding | molecular function | GO:0035197 | 11 | 5 | 17224 | 2647 |
FAM172A,MBD2,MECP2,AGO2,DHX9 |
| 1.754e-02 | -4.04 | Vasopressin-regulated water reabsorption | KEGG pathways | ko04962 | 44 | 13 | 7161 | 1149 |
GNAS,NSF,RAB11B,DYNLL1,DCTN2,ADCY9,ARHGDIB,CREB1,PRKACA,RAB5B,RAB11A,DYNC1LI2,DCTN1 |
| 1.754e-02 | -4.04 | Vasopressin-regulated water reabsorption | KEGG pathways | hsa04962 | 44 | 13 | 7161 | 1149 |
GNAS,NSF,RAB11B,DYNLL1,DCTN2,ADCY9,ARHGDIB,CREB1,PRKACA,RAB5B,RAB11A,DYNC1LI2,DCTN1 |
| 1.755e-02 | -4.04 | TGM2 (transglutaminase 2) | protein interactions | 7052 | 101 | 25 | 17029 | 2761 |
EIF5A,RHOA,VHL,HNRNPF,UBE2V1,MCM2,CDK11B,APP,TWISTNB,HSPA1B,ANKRD28,RB1,KPNA4,SMAD2,FNTA,RBM25,TAB2,ITGB1,YWHAZ,ACTB,PLOD3,MVP,ABCA1,TUBB,LDHB |
| 1.755e-02 | -4.04 | SVIL (supervillin) | protein interactions | 6840 | 106 | 26 | 17029 | 2761 |
USP7,NDUFV2,MIF4GD,MAPRE1,ADD1,SEPT9,CENPF,FLOT1,MYH9,KRAS,CAPZA2,COA7,ANLN,LYN,LMNA,STARD9,KIF14,ODF2,MYO18A,DAPK1,ACTB,KIF22,CDK2,LUC7L2,IFI16,SPTAN1 |
| 1.759e-02 | -4.04 | TPR | prosite domains | PS50005 | 106 | 23 | 12060 | 1670 |
SRP72,RPAP3,NASP,ST13,LONRF3,KLC1,CDC23,TANC1,TTC33,PEX5,CDC16,CDC27,TTC13,ZC3H7B,TTC9C,OGT,CTR9,FKBP5,ANAPC7,CABIN1,TTC3,TTC17,PPP5C |
| 1.762e-02 | -4.04 | - | gene3d domains | 3.40.850.10 | 78 | 20 | 8148 | 1295 |
KIF3B,KIF15,KIF23,MYH9,MYO9B,KIF2C,KIF11,MYO1F,KIF5B,KIF2A,KIFC1,STARD9,KIF18A,KIF18B,KIF13B,KIF14,MYO18A,KIF22,MYO9A,MYO5A |
| 1.768e-02 | -4.04 | positive regulation of macroautophagy | biological process | GO:0016239 | 61 | 16 | 17256 | 2622 |
TSC2,SCOC,PIP4K2C,ADRB2,BECN1,PIP4K2A,EPM2A,SH3GLB1,OPTN,MAPK3,MFN2,TSC1,RALB,LRSAM1,SMURF1,CDC37 |
| 1.770e-02 | -4.03 | human chr11q13.2 | chromosome location | human chr11q13.2 | 78 | 15 | 26185 | 2809 |
YIF1A,BRMS1,ALDH3B1,NUDT8,NDUFV1,ANKRD13D,GRK2,KDM2A,CDK2AP2,NDUFS8,LRP5,PPP6R3,MRPL11,RBM4,CHKA |
| 1.772e-02 | -4.03 | ST_P38_MAPK_PATHWAY | MSigDB lists | ST_P38_MAPK_PATHWAY | 37 | 11 | 17377 | 2626 |
MAP3K4,MKNK1,CDC42,TAB2,CREB1,MAP3K5,ELK1,MAPK14,MAPK1,MYEF2,EEF2K |
| 1.772e-02 | -4.03 | GNF2_TPT1 | MSigDB lists | GNF2_TPT1 | 37 | 11 | 17377 | 2626 |
RPL37,RPS2,RPL32,RPS14,RPLP1,RPS10,RPL38,RPS24,RPL19,RPL27A,RPL23A |
| 1.772e-02 | -4.03 | MA_MYELOID_DIFFERENTIATION_UP | MSigDB lists | MA_MYELOID_DIFFERENTIATION_UP | 37 | 11 | 17377 | 2626 |
GNAS,RB1,MDM2,VASP,CREG1,DHPS,DAD1,PPM1G,PTPN11,EMP3,KLF13 |
| 1.772e-02 | -4.03 | MURAKAMI_UV_RESPONSE_6HR_UP | MSigDB lists | MURAKAMI_UV_RESPONSE_6HR_UP | 37 | 11 | 17377 | 2626 |
PTPRF,PFDN5,ERCC1,CASP6,RAC1,MAPK6,DAPK1,MCL1,SEPT7,MAPK14,CDC37 |
| 1.772e-02 | -4.03 | GNF2_ICAM3 | MSigDB lists | GNF2_ICAM3 | 37 | 11 | 17377 | 2626 |
TMEM127,WAS,MAX,GMFG,HLA-E,STAT6,EMP3,DAZAP2,ARRB2,GIT2,MYO1F |
| 1.772e-02 | -4.03 | CHESLER_BRAIN_HIGHEST_EXPRESSION | MSigDB lists | CHESLER_BRAIN_HIGHEST_EXPRESSION | 37 | 11 | 17377 | 2626 |
SP3,HNRNPA2B1,ATP6V0B,HINT1,CSRP1,ATP13A3,ZRANB2,ACTB,GLO1,ANKRD13C,MATR3 |
| 1.772e-02 | -4.03 | VARELA_ZMPSTE24_TARGETS_UP | MSigDB lists | VARELA_ZMPSTE24_TARGETS_UP | 37 | 11 | 17377 | 2626 |
ERF,BTG2,GADD45B,GADD45G,CIRBP,CRCP,BCL2L1,SLC20A1,NCDN,CSNK1D,PI4K2A |
| 1.772e-02 | -4.03 | GO_SPINDLE_LOCALIZATION | MSigDB lists | GO_SPINDLE_LOCALIZATION | 37 | 11 | 17377 | 2626 |
ASPM,EYA1,ACTR3,MAP4,MYH9,ARHGEF2,NUSAP1,WDR81,NDE1,ESPL1,SPAG5 |
| 1.776e-02 | -4.03 | human chr7q22.1 | chromosome location | human chr7q22.1 | 143 | 24 | 26185 | 2809 |
DNAJC2,ORAI2,PDAP1,ATP5MF,SLC12A9,ARPC1A,GNB2,SRRT,GIGYF1,TRIM4,MOSPD3,POLR2J,ZKSCAN1,POP7,LAMTOR4,CNPY4,BUD31,UPK3BL1,AP1S1,PLOD3,CPSF4,COPS6,TAF6,SMURF1 |
| 1.777e-02 | -4.03 | Immune System | REACTOME pathways | R-HSA-168256 | 2101 | 379 | 10287 | 1696 |
RAB14,TXN,NUP188,TSC2,ADAM10,PRKCSH,HEXB,TAP1,CUL1,NHLRC3,GYG1,CMTM6,POLR3K,FBXO22,CALM2,PA2G4,PSMD1,AP1M1,DNM2,FBXW2,AP2B1,NUP153,KCNAB2,PCBP2,SEH1L,MLST8,ORAI2,NRAS,AKT2,ARHGAP45,KIF15,MCL1,CCNF,WAS,RPS27A,PSMD8,LIMK1,TPP2,ITGB1,ATP6V0C,RNASEL,KLHL42,FBXL3,ARRB2,AAAS,SVIP,DDX58,DNAJC5,GMFG,POLR2K,SEC61G,HLA-E,VAV2,DHX9,KIF23,B4GALT1,MAN2B1,PSEN1,PSMD9,ITGB5,TMEM179B,GNS,CD59,MEX3C,KLHL5,ZNRF2,ARPC5,FBXO7,ATP6V0A2,OSTF1,FBXL7,RNF135,MVP,LPCAT1,NUP85,SOCS5,CYFIP1,FTL,MAPKAPK3,PIP4K2C,C1orf35,CAPZA2,PKM,CYFIP2,ELK1,MAP2K2,CCT8,PSMB3,XRCC5,SEC31A,CAT,KPNA1,DUSP3,CSK,ACLY,PPP3R1,GPI,RNF14,NUP58,RHOG,TRIM41,NDC1,UBR2,RPS6KA1,RAF1,ACTR3,RAC1,MYH9,NIT2,BCL2L1,AP1B1,PRKACA,CPNE3,APP,CRKL,SHC1,SP100,SIAH1,ADCY9,UBA5,NUP107,CDKN1B,BRI3,TAP2,ANAPC7,MAVS,RNF19A,ATF2,TMBIM1,CFL1,DCTN1,ATP6V1G1,ADCY7,CPNE1,ENPP4,CCT2,SEC61B,POLR2L,CUL3,ATP6V0A1,CDC23,ASB13,PSMB9,PPP2CA,KIF2A,ALDH3B1,CDC16,PPP2R5A,SEC61A1,DSN1,DDOST,JAK1,RAB24,STAT1,TICAM1,TRIM32,PDXK,PPP5C,DYNC1LI2,TUBB,OTUD5,MANBA,BRAP,BTN3A1,SIKE1,AKT1S1,IP6K2,UBE4A,FOXO3,HLA-A,PLPP5,PIP5K1C,PSMD2,PTEN,HUWE1,PTPN11,LTN1,CNN2,UBE3B,MAP3K14,CREB1,FBXL19,CNPY3,UBE2M,SPTAN1,PDPK1,PPP3CA,TNFAIP3,FBXO9,HEBP2,ANAPC2,KIF11,FADD,FBXO21,PLD3,KEAP1,KIF18A,MAGT1,PML,PSAP,CD81,ANAPC4,MIB2,ADA2,UBE2E2,NF1,TRIM11,UBE2Q1,UBE2Z,KIF2C,MAPK14,KCMF1,BIRC2,RAP1A,NUP210,CDC42,EIF4A3,IL6ST,PIK3R2,TXLNA,KIF22,ASB6,TRIM14,TRIM8,RBX1,NCK1,VHL,CYSTM1,UBE2V1,IL12RB1,RAB5B,TRIM4,AGPAT2,BRWD1,CRCP,CAB39,ACTB,KPNA2,CLU,ROCK1,PSMC1,ATP6V0E1,CAPN1,UBE2D3,LAMTOR3,ASAH1,KLC1,MEF2A,RACGAP1,CDK13,PPP3CB,NCKAP1,RAB6A,NUP205,NFATC3,VASP,UBE2Q2,CAPZA1,ORAI1,KIFAP3,BCL2,UBE3C,LRSAM1,ATP6V0D1,CREG1,PSMA1,KRAS,ICAM2,ARPC1A,EIF4G2,ARMC8,ISG15,IRF5,PSMC4,CAND1,CDC27,SNAP23,SIAH2,NLRC5,NUP62,YWHAZ,CTSA,RNF114,KCTD7,WASF2,CYLD,TRAF7,DYNLL1,SMARCA4,IRF3,ATP6V1B2,LYN,VAV1,ATP6V0B,MDM2,PSMA6,PIN1,AHCYL1,ABI1,GM2A,RLIM,TIMP2,BIRC3,CGAS,PSMA8,RAB7A,RNF25,PPIE,PSMB7,WIPF1,NFATC2,NUP155,TOLLIP,BTBD1,SURF4,TAB2,STAT6,PSMD3,CANT1,AP1S1,LTA4H,MAPK1,SMURF1,AP2S1,MIF,KIF3B,TRIP12,KLHL21,RAE1,PDAP1,DCTN2,AGO2,NUP54,MYO9B,ARF1,PIP4K2A,PTPN2,KIF5B,HERC3,IRF4,FGFR3,CTSS,GRK2,KLHL20,SEC24C,TANK,STAT3,CAMK2G,MYO5A,TGFB1,ADAM17,MLEC,RHOA,PRKDC,PRKAR1B,POLR3GL,NEU1,MAPK3,HSPA1B,CTSL,HLA-B,RAB18,FBXO41,KPNA4,ATP6V1D,TRIM26,GOLGA7,BIRC5,ELMO1,SNAP29,KBTBD7,PGRMC1,DTX4,IMPDH1,ATP6V1C1,UBE2C,PGAM1,HRAS,IFI16 |
| 1.778e-02 | -4.03 | GSE360_CTRL_VS_B_MALAYI_HIGH_DOSE_MAC_UP | MSigDB lists | GSE360_CTRL_VS_B_MALAYI_HIGH_DOSE_MAC_UP | 185 | 39 | 17377 | 2626 |
IMMT,NDUFS1,MECP2,SRSF6,HEXB,AP3M2,ENSA,BTN3A1,MAN2B1,XPO7,DCUN1D4,SLC20A1,ITGB5,ERH,PSMD1,SP100,SH3BP1,RALB,CS,SEPT11,AP2B1,ERF,TSPAN31,BTG2,HNRNPF,ATXN1,NUTF2,H2AFV,ARMC8,MBD3,CDK11A,ATP6V1D,CDC16,LTBP4,DUSP3,PIAS2,GPI,AP2S1,PDCD4 |
| 1.778e-02 | -4.03 | GSE41176_UNSTIM_VS_ANTI_IGM_STIM_BCELL_6H_UP | MSigDB lists | GSE41176_UNSTIM_VS_ANTI_IGM_STIM_BCELL_6H_UP | 185 | 39 | 17377 | 2626 |
COMMD10,COX15,GOLIM4,KIAA0100,MUM1,UROD,RRM1,SND1,USP48,APP,SAC3D1,ZNF804A,TNS3,FUT8,SUCLG2,CLTB,DNMT1,TPCN1,CAMK2G,VPS13B,SOCS5,RFC3,FAM172A,CPOX,PARP4,ELP4,RHOT1,EDEM2,NDRG3,HMGN2,RPA1,MKNK1,DNAJC10,DSN1,PRDX3,CERS6,ELMO1,TMED10,ATP6V0C |
| 1.778e-02 | -4.03 | GSE22601_DOUBLE_POSITIVE_VS_CD8_SINGLE_POSITIVE_THYMOCYTE_UP | MSigDB lists | GSE22601_DOUBLE_POSITIVE_VS_CD8_SINGLE_POSITIVE_THYMOCYTE_UP | 185 | 39 | 17377 | 2626 |
CYTIP,LIME1,GMFG,PPP1R12A,SLC41A1,TOR3A,ANKH,GADD45G,KLF13,EZH1,SLC20A1,CRLF3,FAM8A1,C14orf119,MAT2B,GNS,RAB21,PTEN,MBD2,CDKN1B,ATG13,BCL2,UPF2,RNF19A,MAML1,ORAI2,PPP3CA,ETV3,BTG2,OXR1,MFNG,EIF2AK1,STX16,STK17B,ATP1A1,PDLIM1,TAB2,STK38,SNX14 |
| 1.778e-02 | -4.03 | GSE17721_CTRL_VS_GARDIQUIMOD_24H_BMDC_UP | MSigDB lists | GSE17721_CTRL_VS_GARDIQUIMOD_24H_BMDC_UP | 185 | 39 | 17377 | 2626 |
PTMS,LZTR1,MRPL42,GNPDA1,MANBA,UBXN1,ANKH,RAC1,LAMTOR3,GOLM1,HOMER1,SLC38A5,IL6ST,TMEM14C,IFT46,ADCY7,GALC,NQO2,SEPT8,VDAC1,ARPC1A,COMMD4,ASF1B,TFEB,HAUS8,ANKRD10,GALNT2,PDLIM1,MFAP1,NSMCE2,SNAP23,ZNF689,ERGIC3,RNF38,ACAT1,CTSA,RUFY3,SNX14,SLC25A39 |
| 1.778e-02 | -4.03 | GSE17186_MEMORY_VS_CD21LOW_TRANSITIONAL_BCELL_DN | MSigDB lists | GSE17186_MEMORY_VS_CD21LOW_TRANSITIONAL_BCELL_DN | 185 | 39 | 17377 | 2626 |
TCF12,BCL2L12,TBC1D12,ADD1,SLC2A1,PMS2,KLF13,B4GALT1,CFLAR,PTPN2,KDM2A,ARHGEF1,CDC25B,AQR,EIF5,FYTTD1,CSNK1G2,RPL35,DDX24,ANKRD37,SNX2,RFXANK,DNAJC9,POLR3GL,STK17B,NEU1,XRCC5,ZNF317,JAK1,CSK,SNAP29,ARNTL,DNAJC17,LRPPRC,ACBD4,SLAIN1,SNRPG,PDCD4,TIGD2 |
| 1.778e-02 | -4.03 | GSE17301_IFNA2_VS_IFNA5_STIM_ACD3_ACD28_ACT_CD8_TCELL_DN | MSigDB lists | GSE17301_IFNA2_VS_IFNA5_STIM_ACD3_ACD28_ACT_CD8_TCELL_DN | 185 | 39 | 17377 | 2626 |
H2AFZ,C1orf112,RAC1,TRIO,CDCA3,GLUD1,PXMP2,SNRNP25,CLIC4,PSMA6,CCNA2,AHSA1,KIF14,NAA50,ANP32A,YBX1,MDFIC,CYC1,PTGES3,IMPA2,RFC3,RHOBTB3,NSDHL,PRKDC,RPL6,GLO1,SHCBP1,TRIM28,SERP1,SPPL2B,GINS4,GALNT2,DSN1,PSMD8,KPNA2,PIEZO1,RUFY3,TFDP2,POLQ |
| 1.778e-02 | -4.03 | GSE23568_CTRL_VS_ID3_TRANSDUCED_CD8_TCELL_UP | MSigDB lists | GSE23568_CTRL_VS_ID3_TRANSDUCED_CD8_TCELL_UP | 185 | 39 | 17377 | 2626 |
OTUD5,IER2,ASH1L,CHERP,HLA-E,BABAM1,TAP1,SMARCA4,IRF3,MAN2B1,EZH1,MAPK14,RUFY1,TERF2IP,RAB35,GLTP,TTC17,LDHB,CSNK1G2,MLEC,SNX2,CIC,LDB1,WBP2,USP10,VKORC1,CBFA2T2,NDRG3,EIF4G2,SF3A2,MARK2,POLR2A,FAS,ATP1A1,PPP2R5A,SAFB,ITGB1,CANT1,DVL1 |
| 1.778e-02 | -4.03 | GSE27786_NKCELL_VS_NKTCELL_DN | MSigDB lists | GSE27786_NKCELL_VS_NKTCELL_DN | 185 | 39 | 17377 | 2626 |
MIF,USP7,PPCS,RRP15,HMGXB3,MRI1,SIKE1,LANCL1,SLC20A1,SDHA,FAM8A1,TFAP4,MSH2,PDCD2,POLR1B,F2R,EEF1D,CFL1,SMC4,PDLIM2,FAM172A,LONRF3,NSUN2,FAM133B,EIF3G,MFN2,RPL36,AKAP1,SEPT1,PLAA,POLE,CHD3,NLRC5,EXOC4,MBOAT1,PPP5C,RRS1,RNF14,MZT2B |
| 1.778e-02 | -4.03 | GSE13484_UNSTIM_VS_3H_YF17D_VACCINE_STIM_PBMC_DN | MSigDB lists | GSE13484_UNSTIM_VS_3H_YF17D_VACCINE_STIM_PBMC_DN | 185 | 39 | 17377 | 2626 |
HIVEP3,CYTIP,CYLD,LAMTOR3,JMJD6,GGA2,OAT,EIF1B,MIS12,MXD1,DNAJB9,IRF4,NAPG,PSMA6,INPP5A,ETV6,PRC1,NAA50,TPST1,SLC26A2,ST8SIA2,SOCS5,PLK3,DEAF1,SNRPB,COQ10B,PLEC,PITPNB,PEF1,RHEB,FAS,MAGT1,CDC27,GADD45B,VCPIP1,ADAM9,MYL12B,ESPL1,NXT2 |
| 1.778e-02 | -4.03 | GSE41867_NAIVE_VS_DAY6_LCMV_EFFECTOR_CD8_TCELL_DN | MSigDB lists | GSE41867_NAIVE_VS_DAY6_LCMV_EFFECTOR_CD8_TCELL_DN | 185 | 39 | 17377 | 2626 |
UBL3,NCOR2,ASH1L,SCAMP3,DCAF15,CERK,C5orf30,MYH9,CDK13,PPP1R16B,FBRS,PHC2,ARPC5,TMEM8A,F2R,ADCY7,CYTH1,CYFIP1,FAM172A,DENND1B,KIAA0930,ZMYM5,MTMR12,AZI2,SOX4,LUC7L,TSR2,SFXN5,TFEB,TRIM26,HPS5,MYO18A,PTAR1,SIAH2,DVL1,SMG9,AKNA,ZBTB11,MYL12B |
| 1.778e-02 | -4.03 | GSE3982_DC_VS_EFF_MEMORY_CD4_TCELL_UP | MSigDB lists | GSE3982_DC_VS_EFF_MEMORY_CD4_TCELL_UP | 185 | 39 | 17377 | 2626 |
SEPHS2,RAB14,NQO1,UGP2,DAP,TOR3A,TRIO,ARID5A,SDC2,MAN2B1,NANS,SPR,APH1B,APP,PABPC4,CDK5,FKBP1A,TNS3,SLC1A4,CD3EAP,MEA1,DAPK1,DDX31,CYC1,ERCC1,TIMP2,FRAT2,KCNQ1,CAT,SLC19A1,MID1IP1,CERS6,PRDX3,WNT5B,SEL1L,SIL1,PSAP,EHD4,ANXA11 |
| 1.779e-02 | -4.03 | GO_REGULATION_OF_CELLULAR_AMINE_METABOLIC_PROCESS | MSigDB lists | GO_REGULATION_OF_CELLULAR_AMINE_METABOLIC_PROCESS | 87 | 21 | 17377 | 2626 |
NQO1,PSMA8,ACSL3,PSMB7,PSMA1,PSMD9,ODC1,PSMB9,PARK7,PSMB3,PSMC4,PSMD2,PSMA6,PSMD1,PSMD3,PSMD8,OAZ2,SCARB1,LPCAT1,PSMC1,OAZ1 |
| 1.782e-02 | -4.03 | positive regulation of viral release from host cell | biological process | GO:1902188 | 15 | 6 | 17256 | 2622 |
CHMP4B,CHMP2A,SMC3,VPS4A,CHMP2B,DDB1 |
| 1.782e-02 | -4.03 | zymogen inhibition | biological process | GO:0097341 | 15 | 6 | 17256 | 2622 |
BCL2L12,BIRC3,BIRC5,BIRC2,CAST,XIAP |
| 1.782e-02 | -4.03 | inhibition of cysteine-type endopeptidase activity | biological process | GO:0097340 | 15 | 6 | 17256 | 2622 |
BCL2L12,BIRC3,BIRC5,BIRC2,CAST,XIAP |
| 1.782e-02 | -4.03 | positive regulation of exosomal secretion | biological process | GO:1903543 | 15 | 6 | 17256 | 2622 |
CHMP2A,HGS,PDCD6IP,VPS4A,STAM,RAB7A |
| 1.782e-02 | -4.03 | cellular response to nitric oxide | biological process | GO:0071732 | 15 | 6 | 17256 | 2622 |
CCNA2,CDK2,GUCY1B1,MTR,CFLAR,DNM2 |
| 1.782e-02 | -4.03 | positive regulation of double-strand break repair | biological process | GO:2000781 | 15 | 6 | 17256 | 2622 |
MRNIP,TIMELESS,FOXM1,SLF1,SPIDR,SLF2 |
| 1.782e-02 | -4.03 | negative regulation of viral release from host cell | biological process | GO:1902187 | 15 | 6 | 17256 | 2622 |
TRIM26,TRIM32,TRIM8,TRIM28,TRIM11,PML |
| 1.782e-02 | -4.03 | RASIP1 (Ras interacting protein 1) | protein interactions | 54922 | 18 | 7 | 17029 | 2761 |
RACGAP1,SIKE1,RAP1A,PPP1R18,CDC42,HRAS,FGFR1OP2 |
| 1.782e-02 | -4.03 | Gm9174 (cell division cycle 26 pseudogene) | protein interactions | 668450 | 18 | 7 | 17029 | 2761 |
ANAPC2,ANAPC7,CDC16,CDC23,CDC27,ANAPC4,FBXO5 |
| 1.782e-02 | -4.03 | CIC (capicua transcriptional repressor) | protein interactions | 23152 | 18 | 7 | 17029 | 2761 |
GTPBP3,PLK1,ATXN1,EWSR1,ZNRD1,CENPJ,EYA2 |
| 1.782e-02 | -4.03 | KIAA0930 (KIAA0930) | protein interactions | 23313 | 18 | 7 | 17029 | 2761 |
YWHAZ,SIRT2,RAB3IP,USP11,PEF1,YWHAH,APP |
| 1.782e-02 | -4.03 | HIST1H2BO (histone cluster 1 H2B family member o) | protein interactions | 8348 | 18 | 7 | 17029 | 2761 |
MCM2,ARRB2,HEXA,CD81,MCM5,H2AFX,FUBP1 |
| 1.782e-02 | -4.03 | STRIP2 (striatin interacting protein 2) | protein interactions | 57464 | 18 | 7 | 17029 | 2761 |
MOB4,PPP2CA,SIKE1,ZRANB1,STRIP1,APP,FGFR1OP2 |
| 1.782e-02 | -4.03 | FAM49B (family with sequence similarity 49 member B) | protein interactions | 51571 | 18 | 7 | 17029 | 2761 |
UNK,PKM,TALDO1,PCBP1,DNAAF2,RAB3IL1,MAPK6 |
| 1.782e-02 | -4.03 | CREB3L3 (cAMP responsive element binding protein 3 like 3) | protein interactions | 84699 | 18 | 7 | 17029 | 2761 |
CUL1,CSNK2A1,USP7,KPNA2,ATF6,RBX1,CEBPG |
| 1.782e-02 | -4.03 | CGGBP1 (CGG triplet repeat binding protein 1) | protein interactions | 8545 | 18 | 7 | 17029 | 2761 |
RBPJ,SUV39H2,GLRX3,FKBP3,CGGBP1,PLEKHF2,DDB1 |
| 1.782e-02 | -4.03 | URM1 (ubiquitin related modifier 1) | protein interactions | 81605 | 18 | 7 | 17029 | 2761 |
TXNL1,SEC23IP,PTGES3,CDK11B,TBL3,PRDX1,USP5 |
| 1.782e-02 | -4.03 | NSUN5 (NOP2/Sun RNA methyltransferase family member 5) | protein interactions | 55695 | 18 | 7 | 17029 | 2761 |
PTPN2,CDK13,CDC16,PPP6R3,EXOSC1,PTPN11,CDC5L |
| 1.782e-02 | -4.03 | PGM3 (phosphoglucomutase 3) | protein interactions | 5238 | 18 | 7 | 17029 | 2761 |
GLO1,LACTB2,UAP1,APP,BDH1,ZNF746,CUL3 |
| 1.782e-02 | -4.03 | FXYD1 (FXYD domain containing ion transport regulator 1) | protein interactions | 5348 | 18 | 7 | 17029 | 2761 |
THNSL1,ATP1A1,ATP6V1D,PRKACA,NDRG3,GOPC,PTTG1 |
| 1.782e-02 | -4.03 | PHLPP2 (PH domain and leucine rich repeat protein phosphatase 2) | protein interactions | 23035 | 18 | 7 | 17029 | 2761 |
EZR,SNX27,PPP3CA,DMWD,FANCI,WDR48,CUL3 |
| 1.782e-02 | -4.03 | BCL11B (B cell CLL/lymphoma 11B) | protein interactions | 64919 | 18 | 7 | 17029 | 2761 |
NFATC2,RBBP4,NR2F2,MBD3,MTA1,MTA2,HDAC2 |
| 1.782e-02 | -4.03 | ZNF526 (zinc finger protein 526) | protein interactions | 116115 | 18 | 7 | 17029 | 2761 |
BRAP,NLN,AFF1,CDC27,SLC12A9,PCGF6,ZNF574 |
| 1.782e-02 | -4.03 | RBMS2 (RNA binding motif single stranded interacting protein 2) | protein interactions | 5939 | 18 | 7 | 17029 | 2761 |
TRA2B,DDX28,MRPL16,SRSF3,SYNCRIP,EIF4H,CUL3 |
| 1.782e-02 | -4.03 | ANAPC13 (anaphase promoting complex subunit 13) | protein interactions | 25847 | 18 | 7 | 17029 | 2761 |
ANAPC2,ANAPC7,CDC16,CDC23,CDC27,ANAPC4,FBXO5 |
| 1.782e-02 | -4.03 | OSBPL5 (oxysterol binding protein like 5) | protein interactions | 114879 | 18 | 7 | 17029 | 2761 |
HGS,CDC23,YWHAH,OSBPL8,LIMK1,APP,NAGLU |
| 1.782e-02 | -4.03 | CDK5RAP1 (CDK5 regulatory subunit associated protein 1) | protein interactions | 51654 | 18 | 7 | 17029 | 2761 |
CDK5,ARMC8,MATR3,KIAA0930,XRCC5,WWP2,KCTD17 |
| 1.782e-02 | -4.03 | Sart3 (squamous cell carcinoma antigen recognized by T cells 3) | protein interactions | 53890 | 18 | 7 | 17029 | 2761 |
KPNA2,PRPF4,PRPF3,HSPA4,FXR1,EIF4A3,PRPF4B |
| 1.782e-02 | -4.03 | Ncaph (non-SMC condensin I complex, subunit H) | protein interactions | 215387 | 18 | 7 | 17029 | 2761 |
SMC2,ATP5MF,MED10,NCAPG,ESPL1,SMC4,UTP15 |
| 1.785e-02 | -4.03 | ASB5 (ankyrin repeat and SOCS box containing 5) | protein interactions | 140458 | 22 | 8 | 17029 | 2761 |
AKR1B1,RPN1,DNAJA1,ATP5F1B,RAB1A,ATP2A2,PRKDC,LRPPRC |
| 1.785e-02 | -4.03 | SNAI2 (snail family transcriptional repressor 2) | protein interactions | 6591 | 22 | 8 | 17029 | 2761 |
MDM2,PSMD1,PSMD3,PPP6R3,APP,PPP2R2D,PSMC1,HDAC2 |
| 1.785e-02 | -4.03 | PGRMC2 (progesterone receptor membrane component 2) | protein interactions | 10424 | 22 | 8 | 17029 | 2761 |
DERL1,GID8,PMF1,DUSP22,LMNA,ABCC1,EVC2,TMEM216 |
| 1.785e-02 | -4.03 | USP44 (ubiquitin specific peptidase 44) | protein interactions | 84101 | 22 | 8 | 17029 | 2761 |
NCOR2,TCOF1,MRPL40,POLR2G,PSMC1,PTTG1,PSMC4,KRR1 |
| 1.785e-02 | -4.03 | RRAGA (Ras related GTP binding A) | protein interactions | 10670 | 22 | 8 | 17029 | 2761 |
RRAGC,CTU2,TSC1,STAU1,TSC2,MIOS,CDC73,NOL8 |
| 1.785e-02 | -4.03 | TANGO2 (transport and golgi organization 2 homolog) | protein interactions | 128989 | 22 | 8 | 17029 | 2761 |
ADSS,CAT,PPIF,NUTF2,GNPDA1,CFL1,PRDX1,PPA2 |
| 1.785e-02 | -4.03 | STAC3 (SH3 and cysteine rich domain 3) | protein interactions | 246329 | 22 | 8 | 17029 | 2761 |
ANKLE2,ZCCHC10,CSNK2A1,C1orf35,NSD3,JMJD6,NKAPD1,GTF2F1 |
| 1.785e-02 | -4.03 | ATP6V1G1 (ATPase H+ transporting V1 subunit G1) | protein interactions | 9550 | 22 | 8 | 17029 | 2761 |
ATP6V1D,GOLGA2,RAB7A,AP2B1,KLHL18,UBE2V1,APP,CARM1 |
| 1.785e-02 | -4.03 | CYBRD1 (cytochrome b reductase 1) | protein interactions | 79901 | 22 | 8 | 17029 | 2761 |
MYH9,MIER2,FAM136A,RAB7A,MIER1,HDAC2,LMNA,MYO18A |
| 1.785e-02 | -4.03 | KCTD2 (potassium channel tetramerization domain containing 2) | protein interactions | 23510 | 22 | 8 | 17029 | 2761 |
TFAP4,CYLD,HUWE1,CUL3,GTPBP4,KCTD17,ARRDC1,MIS12 |
| 1.785e-02 | -4.03 | JADE2 (jade family PHD finger 2) | protein interactions | 23338 | 22 | 8 | 17029 | 2761 |
CCDC93,ZNF496,CCP110,KAT7,GORASP2,MYO9A,MEAF6,FGFR1OP2 |
| 1.785e-02 | -4.03 | TRPV5 (transient receptor potential cation channel subfamily V member 5) | protein interactions | 56302 | 22 | 8 | 17029 | 2761 |
GCLM,HMGN1,EWSR1,PSPC1,YY1,CREB1,STAT3,GFER |
| 1.785e-02 | -4.03 | SCGN (secretagogin, EF-hand calcium binding protein) | protein interactions | 10590 | 22 | 8 | 17029 | 2761 |
ESYT1,AGGF1,CDC23,ATF2,PHKG2,SNAP23,KIF14,BBX |
| 1.785e-02 | -4.03 | FLI1 (Fli-1 proto-oncogene, ETS transcription factor) | protein interactions | 2313 | 22 | 8 | 17029 | 2761 |
EWSR1,SIAH1,ETV6,PIAS2,BRCA1,ELK1,UBE2I,STYXL1 |
| 1.785e-02 | -4.03 | RRN3 (RRN3 homolog, RNA polymerase I transcription factor) | protein interactions | 54700 | 22 | 8 | 17029 | 2761 |
UBTF,UNK,EIF3L,ACTB,POLR1B,RBM15,CDK2,TWISTNB |
| 1.785e-02 | -4.03 | PAK6 (p21 (RAC1) activated kinase 6) | protein interactions | 56924 | 22 | 8 | 17029 | 2761 |
MDM2,NEK6,CDC42,SNX2,RAC1,YWHAZ,MAPK14,APP |
| 1.785e-02 | -4.03 | COQ7 (coenzyme Q7, hydroxylase) | protein interactions | 10229 | 22 | 8 | 17029 | 2761 |
CHCHD2,BOLA3,CYCS,IDE,COQ4,COQ8A,PITRM1,ECH1 |
| 1.785e-02 | -4.03 | Sart1 (squamous cell carcinoma antigen recognized by T cells 1) | protein interactions | 20227 | 22 | 8 | 17029 | 2761 |
SNRNP200,FBXL6,USP39,PRPF4,PRPF3,ASF1B,DDX23,PDF |
| 1.785e-02 | -4.03 | KLHL8 (kelch like family member 8) | protein interactions | 57563 | 22 | 8 | 17029 | 2761 |
USP7,UBA5,CUL3,ATXN1,RACGAP1,SNRNP70,COPS6,COIL |
| 1.785e-02 | -4.03 | SH3BP1 (SH3 domain binding protein 1) | protein interactions | 23616 | 22 | 8 | 17029 | 2761 |
ARHGAP17,CAPZA2,RHOA,SH3BP1,TRIP10,POT1,TERF1,RAC1 |
| 1.785e-02 | -4.03 | DHX37 (DEAH-box helicase 37) | protein interactions | 57647 | 22 | 8 | 17029 | 2761 |
DDX56,NIFK,MEX3C,ZNF746,ATXN1,PRPF4,DHX15,TERF2 |
| 1.788e-02 | -4.02 | Formation of HIV elongation complex in the absence of HIV Tat | REACTOME pathways | R-HSA-167152 | 52 | 15 | 10287 | 1696 |
CCNK,CTDP1,POLR2I,POLR2J,POLR2G,POLR2L,POLR2K,ELOA,POLR2D,TCEA1,GTF2H2,POLR2A,GTF2F1,SSRP1,SUPT16H |
| 1.798e-02 | -4.02 | Formation of Incision Complex in GG-NER | REACTOME pathways | R-HSA-5696395 | 43 | 13 | 10287 | 1696 |
RPA2,ERCC1,RBX1,RPS27A,SUMO2,CHD1L,XPA,RAD23B,UBE2I,GTF2H2,DDB1,RPA1,RAD23A |
| 1.805e-02 | -4.01 | Removal of the Flap Intermediate | REACTOME pathways | R-HSA-69166 | 14 | 6 | 10287 | 1696 |
POLA2,RPA2,PCNA,PRIM2,RPA1,PRIM1 |
| 1.805e-02 | -4.01 | Leading Strand Synthesis | REACTOME pathways | R-HSA-69109 | 14 | 6 | 10287 | 1696 |
POLA2,PCNA,RFC3,PRIM2,RFC2,PRIM1 |
| 1.805e-02 | -4.01 | Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha) | REACTOME pathways | R-HSA-5358565 | 14 | 6 | 10287 | 1696 |
RPA2,PCNA,MSH6,RPA1,PMS2,MSH2 |
| 1.805e-02 | -4.01 | Polymerase switching on the C-strand of the telomere | REACTOME pathways | R-HSA-174411 | 14 | 6 | 10287 | 1696 |
POLA2,PCNA,RFC3,PRIM2,RFC2,PRIM1 |
| 1.805e-02 | -4.01 | Polymerase switching | REACTOME pathways | R-HSA-69091 | 14 | 6 | 10287 | 1696 |
POLA2,PCNA,RFC3,PRIM2,RFC2,PRIM1 |
| 1.805e-02 | -4.01 | Regulation of necroptotic cell death | REACTOME pathways | R-HSA-5675482 | 14 | 6 | 10287 | 1696 |
BIRC3,BIRC2,FADD,CFLAR,XIAP,FAS |
| 1.806e-02 | -4.01 | positive regulation of mitotic cell cycle | biological process | GO:0045931 | 151 | 33 | 17256 | 2622 |
UBE2E2,KMT2E,PHB2,MECP2,CDT1,CCNB1,BECN1,RAB11A,APP,DTL,RB1,MDM2,PTPN11,H2AFY,CDC25B,TGFB1,BRD4,CUL3,LRP5,NUSAP1,CDC6,USP22,RAD51C,DUSP3,NSMCE2,CDCA5,NUP62,XRCC3,UBE2C,SLF1,GEN1,SLF2,ESPL1 |
| 1.806e-02 | -4.01 | GSE22611_MUTANT_NOD2_VS_CTRL_TRANSDUCED_HEK293T_CELL_DN | MSigDB lists | GSE22611_MUTANT_NOD2_VS_CTRL_TRANSDUCED_HEK293T_CELL_DN | 174 | 37 | 17377 | 2626 |
UBL3,RPS2,RRP15,CLSPN,C1orf112,WDR13,UCK2,WRNIP1,CLUAP1,TNS3,GSDMB,PPIL2,XPA,H2AFY,LTN1,OSTF1,RP2,FAM3A,GNAI2,CTDSP2,CDK12,NUDT4,CIRBP,POLR2D,MYBL2,PSMA1,IL12RB1,RAB22A,SPPL2B,SOCS7,DTWD1,PLD3,HSPB11,MAP4,LPCAT4,YWHAZ,SSRP1 |
| 1.806e-02 | -4.01 | GSE34515_CD16_NEG_VS_POS_MONOCYTE_DN | MSigDB lists | GSE34515_CD16_NEG_VS_POS_MONOCYTE_DN | 174 | 37 | 17377 | 2626 |
PPIB,FGFR1OP,LYRM4,GOLPH3L,RPLP2,MRPS15,UFC1,MRI1,CHD1L,ARFIP2,LMNA,DST,IRF4,COQ4,NDUFS8,CYB5R1,OSTC,TOP1MT,GINS1,SEC61B,SCFD2,MTX1,SNRPA,EIF3K,PON2,BOLA3,TMED10,TULP3,EXOC4,BCL7C,DTX4,RRS1,TMEM14A,PDCD2L,AP2S1,NIPA1,USP13 |
| 1.806e-02 | -4.01 | GSE29618_BCELL_VS_MONOCYTE_DAY7_FLU_VACCINE_UP | MSigDB lists | GSE29618_BCELL_VS_MONOCYTE_DAY7_FLU_VACCINE_UP | 174 | 37 | 17377 | 2626 |
TSC2,TCF3,ANK3,ARGLU1,GGA2,ETS1,PPP1R16B,RAPGEF6,MBD4,SMC3,ADD3,GSDMB,TNFAIP8,PRDM4,CDC25B,SRSF10,POU2AF1,BIRC3,SNX2,GNG7,ITM2A,EZR,EAF2,CYFIP2,ODC1,SLC50A1,RPSA,SH3BP5,PDLIM1,GOLGA8A,FAM3C,AEN,QRSL1,CHMP7,TRAF5,NGLY1,PDCD4 |
| 1.806e-02 | -4.01 | GSE1460_NAIVE_CD4_TCELL_CORD_BLOOD_VS_THYMIC_STROMAL_CELL_UP | MSigDB lists | GSE1460_NAIVE_CD4_TCELL_CORD_BLOOD_VS_THYMIC_STROMAL_CELL_UP | 174 | 37 | 17377 | 2626 |
RPS2,MPHOSPH8,TSC22D3,EIF3D,MCCC1,DHX8,PCSK7,EPHX2,CRLF3,RSAD1,MIS12,C2orf68,PCYOX1L,CCNK,ZNF75D,THADA,SLC44A1,XRCC2,ZDHHC13,NSFL1C,GLE1,SCYL3,PPP6R1,PCBP2,TRIM14,TIMM50,CELSR2,MAPKAPK3,TAOK1,MFNG,SPPL2B,ANKZF1,INF2,DAP3,WAS,IDH3B,CHMP7 |
| 1.806e-02 | -4.01 | GSE2770_TGFB_AND_IL4_VS_IL12_TREATED_ACT_CD4_TCELL_2H_UP | MSigDB lists | GSE2770_TGFB_AND_IL4_VS_IL12_TREATED_ACT_CD4_TCELL_2H_UP | 174 | 37 | 17377 | 2626 |
PDCD6IP,MRPL42,GMFG,UFC1,EIF3D,NACA,TKT,RPL15,HAUS4,NHLRC3,HDDC2,RPL11,SH3BP1,ARPC5,RCSD1,SRI,KIFAP3,RPL19,TCEA1,CTDSP2,CSTF1,RPL29,PHF10,ZFP64,WDR1,MAP7D1,ABHD11,TANC1,RHOT2,SH3BP5,C19orf54,NSA2,ATP1A1,RPL32,CRCP,USF2,RAD51D |
| 1.807e-02 | -4.01 | GO_COFACTOR_METABOLIC_PROCESS | MSigDB lists | GO_COFACTOR_METABOLIC_PROCESS | 317 | 62 | 17377 | 2626 |
GALK1,NADSYN1,COX15,PPCS,SUCLG1,MDH2,MRI1,UROD,MCCC1,TKT,ADPGK,SPR,PMVK,RSAD1,MAT2B,FLAD1,PDXP,GART,COQ4,ATIC,PPCDC,AKR1B1,SUCLG2,AHCY,NFU1,TECR,AHCYL1,TALDO1,GPD1L,DNMT1,TMEM14C,KCNAB2,SLC25A1,LDHB,ACSL5,ELOVL5,PPT1,CPOX,AMD1,ACSL3,LDHA,PFKFB3,EIF2AK1,OGDH,VKORC1,PDHX,MAT2A,SLC19A1,MTHFD2,PRDX5,ACLY,MLYCD,DHTKD1,MDH1,GPI,PDXK,IDH3B,PGAM1,PDSS2,ACSF2,SLC25A39,PFKP |
| 1.809e-02 | -4.01 | malate-aspartate shuttle | BIOCYC pathways | HUMAN_MALATE-ASPARTATE-SHUTTLE-PWY | 4 | 3 | 902 | 157 |
MDH1,GOT2,MDH2 |
| 1.810e-02 | -4.01 | ACAT1 (acetyl-CoA acetyltransferase 1) | protein interactions | 38 | 67 | 18 | 17029 | 2761 |
UNK,ERCC1,CYLD,EWSR1,FOXM1,SIGMAR1,FLOT1,CUL3,CUL1,CYCS,EIF1B,SDHA,SDHB,DUS3L,SAFB,ACAT1,FUS,DDB1 |
| 1.810e-02 | -4.01 | KLHL2 (kelch like family member 2) | protein interactions | 11275 | 67 | 18 | 17029 | 2761 |
TRIM8,SCYL1,DCTN2,XIAP,CUL3,RNPS1,UCK1,APPL1,GIT2,TRIM47,KEAP1,RRBP1,TNPO2,IMPDH1,UPRT,UBE2C,TSPAN5,DCTN1 |
| 1.810e-02 | -4.01 | CDK5RAP2 (CDK5 regulatory subunit associated protein 2) | protein interactions | 55755 | 67 | 18 | 17029 | 2761 |
FGFR1OP,MAGEH1,MAPRE1,REPS2,SUZ12,DYNLL1,PTTG1,TUBGCP5,IKBIP,PRKACA,TUBGCP2,CDK5,STARD9,MZT2A,SOCS6,CHMP4B,MZT2B,LUC7L2 |
| 1.810e-02 | -4.01 | GART (phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase) | protein interactions | 2618 | 67 | 18 | 17029 | 2761 |
COX15,UGP2,CUL3,ADSL,BRCA1,XPO7,MCM2,EIF4H,KDM3A,ADSS,DERL1,HSPA4,GART,ATIC,STAT6,KPNA2,TATDN1,FAF1 |
| 1.810e-02 | -4.01 | ATXN1L (ataxin 1 like) | protein interactions | 342371 | 67 | 18 | 17029 | 2761 |
MBD1,NCOR2,PRRC2A,SUGP2,RRAGC,ATXN1,GORASP2,CBFA2T2,DAZAP2,YY1AP1,HGS,ELP5,ZC3H7B,H2AFY,MBD6,FUS,COIL,ANKHD1 |
| 1.821e-02 | -4.01 | Sphingolipid metabolism | REACTOME pathways | R-HSA-428157 | 90 | 23 | 10287 | 1696 |
CSNK1G2,GALC,HEXB,CERK,GBA,ASAH1,SUMF1,SUMF2,ESYT1,ARSK,NEU1,PRKD3,ALDH3B1,ORMDL2,CERS6,CTSA,GLTP,PSAP,SMPD4,SPTSSA,HEXA,GM2A,ESYT2 |
| 1.822e-02 | -4.01 | BCR signaling pathway | Pathway Interaction DB | bcr_5pathway | 66 | 20 | 2226 | 426 |
PDPK1,PPP3CA,RAF1,RAC1,VAV2,CSNK2A1,PPP3CB,ELK1,ETS1,LYN,MAPK14,MAPK3,SH3BP5,CALM2,SHC1,CSK,PTEN,MAPK1,HRAS,CAMK2G |
| 1.826e-02 | -4.00 | - | gene3d domains | 3.40.50.620 | 40 | 12 | 8148 | 1295 |
FLAD1,CTU2,LARS,EPRS,NADSYN1,IARS,QARS,TRMU,IARS2,CRY2,PCYT2,CARS2 |
| 1.827e-02 | -4.00 | KMCATNNWGGA_UNKNOWN | MSigDB lists | KMCATNNWGGA_UNKNOWN | 82 | 20 | 17377 | 2626 |
TSHZ1,SP3,STRN4,MAP4K3,CSNK1A1,CNOT3,SRSF1,TSC1,SYNCRIP,TMED10,CWC27,TBC1D14,CRAT,ARNTL,ANAPC7,GEMIN4,NR2F2,ZBTB11,CGGBP1,SOCS5 |
| 1.827e-02 | -4.00 | MODULE_204 | MSigDB lists | MODULE_204 | 82 | 20 | 17377 | 2626 |
PGAP2,POU2AF1,FOXM1,GORASP1,TPX2,RRM1,CHKB,MPG,CAND1,DDX23,DDX17,NUP210,GART,PCNA,MSH2,PQBP1,AHDC1,RNASEH2A,HRAS,ABCC5 |
| 1.827e-02 | -4.00 | KAYO_CALORIE_RESTRICTION_MUSCLE_DN | MSigDB lists | KAYO_CALORIE_RESTRICTION_MUSCLE_DN | 82 | 20 | 17377 | 2626 |
BAK1,NDUFV2,POLR2I,VDAC2,COX4I1,TAZ,COPB2,ECH1,CREM,DDX17,GOT2,AXIN1,RAB4A,DBI,HADHB,COX8A,MDH1,CYC1,RRS1,HRAS |
| 1.833e-02 | -4.00 | ANKYRIN | prints domains | PR01415 | 113 | 19 | 4652 | 473 |
MIB2,ANKRD27,PPP1R12A,ANK3,EHMT1,ASB13,TANC1,ANKRD23,ANKRD39,ANKRD28,ANKRD26,TONSL,PPP1R12C,DAPK1,FEM1B,OSTF1,RNASEL,MTPN,ANKHD1 |
| 1.834e-02 | -4.00 | TFIP11 (tuftelin interacting protein 11) | protein interactions | 24144 | 142 | 33 | 17029 | 2761 |
USP7,COX5B,SART1,JMJD6,IKBIP,RCOR3,LMNA,OIP5,MDM2,TXLNA,NFU1,SMARCE1,GCC1,TERF2,PRPF19,PPP1R18,COQ8A,TSPYL4,SNRPB,MTFR2,FAM50B,PRPF3,MPG,EIF3A,SH3GLB1,CENPU,DDX23,GPS2,C1orf109,PRPF4,SNRPG,NDE1,SNRNP70 |
| 1.834e-02 | -4.00 | CENPJ (centromere protein J) | protein interactions | 55835 | 142 | 33 | 17029 | 2761 |
SNX27,TRIO,SEC16A,FBXO22,CALM2,CCP110,KIF14,NABP2,GPATCH1,TP53BP2,PLK1,MOB4,MAPRE2,CCDC138,CIC,CAMSAP1,MRPL12,ADSL,ARMT1,COMMD4,HAUS8,EPB41,PSMC4,GEMIN5,RAB18,PCM1,PFDN4,CEP55,VCPIP1,YWHAZ,BTF3,YWHAH,SASS6 |
| 1.834e-02 | -4.00 | TUBGCP3 (tubulin gamma complex associated protein 3) | protein interactions | 10426 | 142 | 33 | 17029 | 2761 |
RPS15,IMMT,RPS2,MZT1,MRPS2,SEC61G,PPP3CB,PCBP1,SDE2,TUBGCP2,RPL11,RPL23A,MZT2A,CTPS1,ANXA5,CDC5L,PRPF19,PRRC2A,DCAF8,TUBGCP5,RPL8,RPS10,PSMA1,MRPS14,RPS9,MAGED2,RPS14,CEP55,ACTB,DDX5,RBBP4,MZT2B,TUBB |
| 1.835e-02 | -4.00 | GSE17721_POLYIC_VS_CPG_16H_BMDC_UP | MSigDB lists | GSE17721_POLYIC_VS_CPG_16H_BMDC_UP | 191 | 40 | 17377 | 2626 |
UNK,TRIM41,EWSR1,PARP12,TRIP12,TRAF7,GNPDA1,B4GALT5,RHOC,CTCF,TBC1D13,BCL2L1,HOMER1,ADD3,PPP1R8,SLC44A1,POP7,AFF1,RBM3,TNRC18,HNRNPM,TNFAIP3,GALC,DENND4C,TOP3A,ZNF574,GALNT7,SYVN1,ASB13,PDCD6,BRD2,CCDC86,CLK3,CCDC6,NFIL3,STAT1,NCOA1,SLC22A23,BRWD3,ANAPC4 |
| 1.835e-02 | -4.00 | GSE43863_TFH_VS_LY6C_INT_CXCR5POS_MEMORY_CD4_TCELL_UP | MSigDB lists | GSE43863_TFH_VS_LY6C_INT_CXCR5POS_MEMORY_CD4_TCELL_UP | 191 | 40 | 17377 | 2626 |
AGRN,B4GALT5,SRGN,TAP1,CSNK2A1,AGFG1,BCL2L1,CHAC2,STAM,TFRC,NUP205,RGS1,JMY,DNAJB9,LIN9,MDM2,PDCD10,CBWD2,ATP2A2,CITED2,TFG,MCPH1,TMEM39A,TOP3A,MYBL2,SLC25A22,ASB13,DHX15,ISG15,ARF4,CCDC127,UAP1,PFDN4,MAFK,U2SURP,TFDP1,USP32,PML,LY75,SLC25A33 |
| 1.835e-02 | -4.00 | GSE33425_CD8_ALPHAALPHA_VS_ALPHABETA_CD161_HIGH_TCELL_UP | MSigDB lists | GSE33425_CD8_ALPHAALPHA_VS_ALPHABETA_CD161_HIGH_TCELL_UP | 191 | 40 | 17377 | 2626 |
SLC30A9,UBL3,RAB14,ASH1L,IMMT,MIF4GD,EYA1,TRIM11,EIF2AK4,GGA2,OAT,CRLF3,RUFY1,LYN,KTN1,GNS,CTSS,STRBP,RALB,TBC1D14,PPIF,POU2AF1,PLK3,SNX2,ELL2,SLC16A7,WBP2,MCL1,CBFA2T2,EIF4G2,IRF5,MKNK1,TXNDC16,SAFB,NAGLU,PITPNA,B4GALT3,CD81,HEXA,ABCA1 |
| 1.835e-02 | -4.00 | GSE17721_LPS_VS_CPG_16H_BMDC_DN | MSigDB lists | GSE17721_LPS_VS_CPG_16H_BMDC_DN | 191 | 40 | 17377 | 2626 |
PPP1R37,MUT,MAGED1,SLC39A13,BRIX1,STMN1,PABPC4,LMNA,SSR1,MAN1A1,RAP1A,NUP210,ADD3,COQ4,RPL19,TARDBP,MRPL40,AHCYL1,TFG,ABCC1,PLK1,PHF10,CREG1,PBK,WBP2,SEPT8,RRM2,NUTF2,SEPT7,SERP1,SNRPA,BTBD1,TRAM2,DAP3,UEVLD,DUSP3,SEL1L,PRMT7,ST3GAL2,PITRM1 |
| 1.835e-02 | -4.00 | GSE17721_CTRL_VS_CPG_4H_BMDC_DN | MSigDB lists | GSE17721_CTRL_VS_CPG_4H_BMDC_DN | 191 | 40 | 17377 | 2626 |
CHMP2A,TXN,SUZ12,PAWR,NOTCH2,CUTC,CHD1,KTN1,PHC2,LIN9,EIF2S2,CBWD2,RNFT1,DDA1,PTPN11,OSTF1,AFF1,UPF2,CLDND1,CHTOP,PLCL2,MYBL1,HDHD2,TXNL1,HMGN5,ELL2,NFATC2IP,TANC1,ARF4,PI4K2A,MTHFD2,KEAP1,PLAA,TAB2,PRDX5,PML,DUSP11,RUFY3,IGBP1,NMD3 |
| 1.835e-02 | -4.00 | GSE13306_TREG_VS_TCONV_LAMINA_PROPRIA_UP | MSigDB lists | GSE13306_TREG_VS_TCONV_LAMINA_PROPRIA_UP | 191 | 40 | 17377 | 2626 |
PPIB,C9orf78,DNMT3A,ZNF768,DNAJB2,FAM129A,TRIM11,UBXN1,VAV2,CREBL2,B4GALT4,CPNE3,PARK7,HLA-A,RGS1,SLC25A36,PRNP,GNS,RNF121,GLIS2,HUWE1,SNX18,RABGAP1L,SLC44A1,MEA1,PTPN11,CLTB,LPCAT1,PRKAR1B,ODC1,RHOB,ARF4,MAGED2,UAP1,AGPAT2,HIPK2,SIL1,ST3GAL2,TSEN15,TOB1 |
| 1.840e-02 | -4.00 | GO_REGULATION_OF_CHROMATIN_ORGANIZATION | MSigDB lists | GO_REGULATION_OF_CHROMATIN_ORGANIZATION | 152 | 33 | 17377 | 2626 |
TRIP12,KDM4A,MECP2,CTCF,CCNB1,AKAP8,ZNF335,NOC2L,H2AFY,CTR9,BRD7,CHTOP,DNMT1,TGFB1,KAT2A,EID1,MIER1,TLK1,WBP2,RTF1,BRCA1,KDM3A,TRIM28,IWS1,MAPK3,PAF1,ATAD2,UHRF2,OGT,PML,RUVBL2,PARP10,SMAD4 |
| 1.845e-02 | -3.99 | GO_PLACENTA_BLOOD_VESSEL_DEVELOPMENT | MSigDB lists | GO_PLACENTA_BLOOD_VESSEL_DEVELOPMENT | 28 | 9 | 17377 | 2626 |
PKD2,ARID1A,RBPJ,NR2F2,ITGB8,RBM15,MAPK1,NSDHL,TMED2 |
| 1.845e-02 | -3.99 | BURTON_ADIPOGENESIS_10 | MSigDB lists | BURTON_ADIPOGENESIS_10 | 28 | 9 | 17377 | 2626 |
STRBP,ANXA6,NSDHL,FLOT1,GYG1,ATP6V1C1,CPEB2,RAB3IL1,FDFT1 |
| 1.845e-02 | -3.99 | GO_ATPASE_REGULATOR_ACTIVITY | MSigDB lists | GO_ATPASE_REGULATOR_ACTIVITY | 28 | 9 | 17377 | 2626 |
HSPH1,DNAJC10,DNAJC2,AHSA1,RAB4A,TOR1AIP1,DNAJC24,TOR1AIP2,DNAJB1 |
| 1.845e-02 | -3.99 | GO_NECROTIC_CELL_DEATH | MSigDB lists | GO_NECROTIC_CELL_DEATH | 28 | 9 | 17377 | 2626 |
PPIF,CYLD,TICAM1,IRF3,SIRT2,MAP3K5,BIRC2,FADD,FAS |
| 1.845e-02 | -3.99 | BIOCARTA_HDAC_PATHWAY | MSigDB lists | BIOCARTA_HDAC_PATHWAY | 28 | 9 | 17377 | 2626 |
CALM2,PPP3CA,MEF2A,NFATC2,CABIN1,MEF2D,PPP3CB,YWHAH,MAPK14 |
| 1.845e-02 | -3.99 | GO_PROTEIN_LOCALIZATION_TO_CYTOSKELETON | MSigDB lists | GO_PROTEIN_LOCALIZATION_TO_CYTOSKELETON | 28 | 9 | 17377 | 2626 |
MAPRE1,PCM1,CCDC14,KLHL21,DCTN2,FAM83D,DVL1,SPAG5,CSNK1D |
| 1.845e-02 | -3.99 | PID_TCR_CALCIUM_PATHWAY | MSigDB lists | PID_TCR_CALCIUM_PATHWAY | 28 | 9 | 17377 | 2626 |
FKBP1A,PPP3CA,NFATC3,PPP3R1,CABIN1,NFATC2,PPP3CB,PRKACA,CREM |
| 1.845e-02 | -3.99 | GO_TELOMERIC_DNA_BINDING | MSigDB lists | GO_TELOMERIC_DNA_BINDING | 28 | 9 | 17377 | 2626 |
TERF2IP,HNRNPA2B1,UPF1,UPF2,PURA,TERF1,POT1,XRCC5,TERF2 |
| 1.845e-02 | -3.99 | REACTOME_MRNA_CAPPING | MSigDB lists | REACTOME_MRNA_CAPPING | 28 | 9 | 17377 | 2626 |
POLR2I,POLR2G,POLR2L,POLR2J,POLR2K,POLR2D,GTF2H2,POLR2A,GTF2F1 |
| 1.845e-02 | -3.99 | GUILLAUMOND_KLF10_TARGETS_DN | MSigDB lists | GUILLAUMOND_KLF10_TARGETS_DN | 28 | 9 | 17377 | 2626 |
ELOVL5,CTSS,SEC61A1,VMP1,AACS,OGT,SRSF3,OSTC,CHPT1 |
| 1.845e-02 | -3.99 | GO_PRE_AUTOPHAGOSOMAL_STRUCTURE | MSigDB lists | GO_PRE_AUTOPHAGOSOMAL_STRUCTURE | 28 | 9 | 17377 | 2626 |
ULK3,VMP1,ATG9A,RB1CC1,RAB7A,ATG2B,ATG13,WIPI2,BECN1 |
| 1.848e-02 | -3.99 | ligand-dependent nuclear receptor binding | molecular function | GO:0016922 | 19 | 7 | 17224 | 2647 |
SLC30A9,NCOR2,NCOA1,ARID1A,BAZ2A,SMARCE1,NCOA2 |
| 1.848e-02 | -3.99 | MHC class I protein binding | molecular function | GO:0042288 | 19 | 7 | 17224 | 2647 |
DERL1,ATP5F1A,ATP5F1B,HLA-E,BCAP31,TUBB,TAP1 |
| 1.848e-02 | -3.99 | CPDc | smart domains | SM00577 | 8 | 4 | 9493 | 1367 |
CTDP1,CTDSP2,TIMM50,UBLCP1 |
| 1.848e-02 | -3.99 | PIPKc | smart domains | SM00330 | 8 | 4 | 9493 | 1367 |
PIKFYVE,PIP4K2A,PIP5K1C,PIP4K2C |
| 1.848e-02 | -3.99 | BIR | smart domains | SM00238 | 8 | 4 | 9493 | 1367 |
BIRC3,BIRC5,BIRC2,XIAP |
| 1.848e-02 | -3.99 | Ubox | smart domains | SM00504 | 8 | 4 | 9493 | 1367 |
UBE4B,UBE4A,PPIL2,PRPF19 |
| 1.850e-02 | -3.99 | Follicle Stimulating Hormone (FSH) signaling pathway | WikiPathways | WP2035 | 27 | 9 | 5312 | 837 |
TSC2,RAF1,CREB1,PRKACA,MAPK14,MAPK1,APPL1,RHEB,MAPK3 |
| 1.855e-02 | -3.99 | GET4 (golgi to ER traffic protein 4) | protein interactions | 51608 | 53 | 15 | 17029 | 2761 |
PLK1,KIF2A,PTMS,KEAP1,SEC61B,PRKCSH,HUWE1,MTA2,FLYWCH2,UBXN1,LSM8,ASNA1,PRMT2,FAF1,USP13 |
| 1.855e-02 | -3.99 | NSD3 (nuclear receptor binding SET domain protein 3) | protein interactions | 54904 | 53 | 15 | 17029 | 2761 |
TGFB1,BRD4,ETV3,BRD2,RB1CC1,BCL7C,H2AFY,SMARCA4,SS18L1,CHEK2,UBE2I,KDM1B,BRD9,CDKN2A,CBX3 |
| 1.855e-02 | -3.99 | HOMER3 (homer scaffold protein 3) | protein interactions | 9454 | 53 | 15 | 17029 | 2761 |
WASF2,HOMER1,PPP1R18,EIF3D,PML,NUP54,PSMA1,WIPF1,NCKAP1,CYFIP2,YWHAH,POLG2,ABI1,APP,SRPK2 |
| 1.855e-02 | -3.99 | KLHDC3 (kelch domain containing 3) | protein interactions | 116138 | 53 | 15 | 17029 | 2761 |
AFDN,EIF4ENIF1,LUZP1,RAD18,FOXK1,TSPYL4,DPYSL2,POP7,BRAP,RPL15,USP10,DIDO1,COPS6,SYMPK,DAPK3 |
| 1.855e-02 | -3.99 | NPEPPS (aminopeptidase puromycin sensitive) | protein interactions | 9520 | 53 | 15 | 17029 | 2761 |
STAU1,RPLP2,RPS6KA1,ZNF746,CAMKMT,CUL3,BRCA1,NANS,DMWD,CLN3,CDK2,NIPSNAP2,STRAP,PHKG2,LDHB |
| 1.855e-02 | -3.99 | METAP2 (methionyl aminopeptidase 2) | protein interactions | 10988 | 53 | 15 | 17029 | 2761 |
GNAS,DDX28,CDC42,CHD3,GPBP1L1,E2F4,MECP2,RAC1,KRAS,RGS2,MAPK1,APP,ASB6,MAPK3,EEF2K |
| 1.855e-02 | -3.99 | TRIM44 (tripartite motif containing 44) | protein interactions | 54765 | 53 | 15 | 17029 | 2761 |
TRIM47,TRAF7,GOLGA2,DDX24,TRIM11,BBX,TXLNA,CDCA8,FEM1B,MICU2,KRAS,KANSL2,ZNF761,APP,ZNF92 |
| 1.857e-02 | -3.99 | GO_COENZYME_METABOLIC_PROCESS | MSigDB lists | GO_COENZYME_METABOLIC_PROCESS | 248 | 50 | 17377 | 2626 |
GALK1,NADSYN1,PPCS,SUCLG1,MDH2,MRI1,TKT,ADPGK,SPR,PMVK,MAT2B,FLAD1,GART,COQ4,ATIC,PPCDC,SUCLG2,AHCY,TECR,TALDO1,AHCYL1,GPD1L,DNMT1,KCNAB2,SLC25A1,LDHB,ACSL5,ELOVL5,PPT1,AMD1,ACSL3,LDHA,PFKFB3,OGDH,PDHX,MAT2A,SLC19A1,MTHFD2,PRDX5,ACLY,DHTKD1,MLYCD,MDH1,GPI,PDXK,IDH3B,PGAM1,PDSS2,ACSF2,PFKP |
| 1.862e-02 | -3.98 | membrane docking | biological process | GO:0022406 | 179 | 38 | 17256 | 2622 |
FGFR1OP,NPHP4,MAPRE1,DYNLL1,DCTN2,VPS45,HAUS4,PRKACA,RAB11A,HAUS2,RAB8A,CCP110,CENPJ,CEP63,DCTN1,CHP1,PLK1,USO1,RAB7A,TMEM216,SCFD2,EZR,ESYT1,RAB3IP,STX16,HAUS8,PCM1,NSF,SNAP29,ODF2,EXOC4,SSNA1,ROCK1,NDE1,UNC13C,TUBB,CSNK1D,ESYT2 |
| 1.864e-02 | -3.98 | ZNF512B (zinc finger protein 512B) | protein interactions | 57473 | 72 | 19 | 17029 | 2761 |
ANKLE2,MBD1,KDM3B,KLF10,CDC123,VHL,PBRM1,GLRX3,ANKRD28,PTPRF,APLP2,KDM2A,RPS27A,SIAH1,MTA1,UBA5,KMT2B,SMAD1,DCTN1 |
| 1.864e-02 | -3.98 | HAUS7 (HAUS augmin like complex subunit 7) | protein interactions | 55559 | 72 | 19 | 17029 | 2761 |
GOLIM4,ASPM,DHX29,HAUS4,SPDL1,HAUS2,HAUS8,LEMD2,CEP104,PCM1,CDC16,UCHL5,CENPJ,ODF2,CEP63,SASS6,POC5,CDC5L,DCTN1 |
| 1.864e-02 | -3.98 | GLYR1 (glyoxylate reductase 1 homolog) | protein interactions | 84656 | 72 | 19 | 17029 | 2761 |
CCNC,PPAN,STAU1,SUZ12,DHX9,RPL8,TOP2B,NSD3,KDM1B,RBM4,DGCR8,RBM34,NOC2L,GEMIN4,RRS1,FBL,ZC3HAV1,IFI16,GPATCH4 |
| 1.867e-02 | -3.98 | HALLMARK_WNT_BETA_CATENIN_SIGNALING | MSigDB lists | HALLMARK_WNT_BETA_CATENIN_SIGNALING | 42 | 12 | 17377 | 2626 |
NCOR2,ADAM17,KAT2A,WNT5B,AXIN1,AXIN2,CUL1,RBPJ,MAML1,HDAC2,DVL2,NUMB |
| 1.867e-02 | -3.98 | ZUCCHI_METASTASIS_DN | MSigDB lists | ZUCCHI_METASTASIS_DN | 42 | 12 | 17377 | 2626 |
HMGN1,SEC61B,RHOA,SEPT9,PDLIM1,GADD45B,PPM1G,CDK2AP2,STRN4,DDX5,EIF3G,DDB1 |
| 1.867e-02 | -3.98 | ZHAN_EARLY_DIFFERENTIATION_GENES_DN | MSigDB lists | ZHAN_EARLY_DIFFERENTIATION_GENES_DN | 42 | 12 | 17377 | 2626 |
RHOG,MKNK1,FOXM1,RAE1,MSH2,CCNF,TRAF5,ETS1,OGG1,HRAS,TERF2,RPA1 |
| 1.867e-02 | -3.98 | REACTOME_TRNA_AMINOACYLATION | MSigDB lists | REACTOME_TRNA_AMINOACYLATION | 42 | 12 | 17377 | 2626 |
FARSA,KARS,EPRS,LARS,IARS,HARS,QARS,PPA2,IARS2,PPA1,TARS,CARS2 |
| 1.870e-02 | -3.98 | GSE26290_WT_VS_PDK1_KO_ANTI_CD3_AND_IL2_STIM_CD8_TCELL_UP | MSigDB lists | GSE26290_WT_VS_PDK1_KO_ANTI_CD3_AND_IL2_STIM_CD8_TCELL_UP | 180 | 38 | 17377 | 2626 |
ZNF76,ANKRD27,CKLF,MECP2,TMX4,TRAK1,SMARCA4,DNAJB1,SNN,MAN1A1,CD59,SLC31A1,EXOSC7,SYNM,SLC44A1,FBXO7,PHTF1,BCAP29,TECR,PABPC1,TPCN1,RPP25,NXT1,TSTA3,MAPKAPK3,TSPYL4,VHL,MAP4K4,KDM1B,ODC1,TRIM47,FBXO41,COX5A,FAM126A,RBPJ,MAP3K5,RNF139,ZSWIM6 |
| 1.870e-02 | -3.98 | GSE17721_POLYIC_VS_GARDIQUIMOD_2H_BMDC_UP | MSigDB lists | GSE17721_POLYIC_VS_GARDIQUIMOD_2H_BMDC_UP | 180 | 38 | 17377 | 2626 |
NSMCE4A,SHPRH,TIA1,NOTCH2,GGPS1,BIRC2,MBD4,CAPN2,DTL,KLF16,RAB4A,GEMIN6,CPSF4,TIPARP,S100A6,MED22,SMC4,FDFT1,TMEM115,TSTA3,WIPF1,EMP3,BCLAF1,ARID1A,ISG15,IRF5,GIGYF1,ANKRD10,RPLP1,SIL1,TMEM219,RBMS1,TCOF1,ZNF830,BRWD3,TSPAN5,TSEN15,PRPF4B |
| 1.870e-02 | -3.98 | GSE22229_RENAL_TRANSPLANT_IMMUNOSUPP_THERAPY_VS_HEALTHY_PBMC_DN | MSigDB lists | GSE22229_RENAL_TRANSPLANT_IMMUNOSUPP_THERAPY_VS_HEALTHY_PBMC_DN | 180 | 38 | 17377 | 2626 |
MANBA,UFC1,SLC25A12,B4GALT1,SDF2L1,FKBP2,B4GALT4,CFLAR,PCYOX1L,CSDE1,RALB,RRBP1,EFCAB11,FAM76B,ACAD8,CREB1,NAGPA,TACC1,NEK7,WDR1,ERLIN1,PPP1R21,KCTD20,RAB3IP,NEU1,RAD51C,HNRNPR,ZNF330,PRDX5,FKBP5,ATF6,KLHDC4,PLOD3,CCDC125,LTA4H,LRP8,PFKP,SVIP |
| 1.870e-02 | -3.98 | GSE34515_CD16_NEG_VS_POS_MONOCYTE_UP | MSigDB lists | GSE34515_CD16_NEG_VS_POS_MONOCYTE_UP | 180 | 38 | 17377 | 2626 |
CASP6,UQCR10,ANKH,CUTA,NUP54,MED13L,AGPAT3,BZW2,MAN1A1,IRF4,DDX56,CLIC4,INPP5A,IL6ST,DUT,ATIC,COPS7B,OSTC,NDUFA3,NAGPA,SEPT9,SIGMAR1,NSDHL,TUFM,TBRG4,HEBP2,ATP6V0A1,EAF2,SMAP2,NFIL3,MRPL27,COX8A,SLC16A1,FKBP5,TRAF5,EYA2,RAB3IL1,PFKP |
| 1.871e-02 | -3.98 | MARTINEZ_RB1_TARGETS_DN | MSigDB lists | MARTINEZ_RB1_TARGETS_DN | 501 | 93 | 17377 | 2626 |
TMEM106C,ZBED3,MAX,PIGQ,PTTG1,TMEM109,DUSP22,GIT2,PRNP,RRN3,ATP2A2,SIVA1,MTA1,RAB4A,SLC44A1,PPCDC,AP2B1,TARDBP,AQR,MARCH2,ASB6,CLCN3,MAPRE2,CELSR2,SREK1,PFKFB3,MCL1,GLO1,BICD2,TXNL4A,CLNS1A,ACYP1,TMED10,MAP4,LMBR1,ATP6V0C,FKBP5,CLU,CHEK2,DVL1,SMAD4,CCDC137,FUBP1,SEPHS2,PPIB,ZCCHC9,DAP,SRGN,SCYL1,TIA1,SLC35B1,LANCL1,PDCD7,PIP4K2A,FZD6,PIP5K1C,NDUFS4,FERMT3,LYAR,HUWE1,EFTUD2,TNPO3,SLC27A4,ACAD8,MAML1,CPSF4,LPCAT1,IFT46,MORC3,LDHB,TIMMDC1,RDH10,ABCF2,ILF3,ZNF574,MYBL2,RPS24,MTX1,PTTG1IP,SPPL2B,POLR2A,PRDX1,NCDN,PSMC4,PTPRF,EPRS,GOLGA4,FNTA,ZNF330,SRSF3,RBBP4,RNF14,HRAS |
| 1.872e-02 | -3.98 | MODULE_53 | MSigDB lists | MODULE_53 | 388 | 74 | 17377 | 2626 |
TMEM106C,FOXM1,PTTG1,SLC2A1,TAP1,TPX2,C5orf30,CSNK2A1,PTP4A3,KIF2C,CCNB1,STMN1,KIFC1,CDKN2C,PCNA,CCNA2,SH3BP1,KIF14,AP1M1,CDC25B,CORO1A,RNASEH2A,DNMT1,HTRA2,PRPF19,PLK1,RFC3,GNG7,MKI67,RRM2,ARHGDIB,PKMYT1,SOX4,MCM2,CCNF,CHAF1A,PRIM1,ZMYM3,PTPN7,H2AFX,DVL1,ABCA1,SRGN,CENPF,KCTD17,RRM1,BLM,WRB,RGS1,NUP205,SAC3D1,MSH2,GTSE1,KNTC1,TMX1,MSH6,GINS1,CREG1,PRKDC,ILF3,MYBL2,EMP3,ADSL,ARID1A,KIF11,ISG15,RBM38,RPA1,ETS2,SYNCRIP,E2F1,CDK2,UBE2C,CCNB2 |
| 1.872e-02 | -3.98 | FRIDMAN_SENESCENCE_UP | MSigDB lists | FRIDMAN_SENESCENCE_UP | 77 | 19 | 17377 | 2626 |
GUK1,TNFAIP3,CREG1,RAC1,HTATIP2,MAP1LC3B,RAB5B,RHOB,IRF5,ISG15,OPTN,MDM2,EIF2S2,HPS5,STAT1,CLTB,CITED2,CDKN2A,IFI16 |
| 1.879e-02 | -3.97 | prenyltransferase activity | molecular function | GO:0004659 | 15 | 6 | 17224 | 2647 |
FNTA,NUS1,GGPS1,PGGT1B,FDFT1,PTAR1 |
| 1.879e-02 | -3.97 | DNA N-glycosylase activity | molecular function | GO:0019104 | 15 | 6 | 17224 | 2647 |
PCNA,MPG,OGG1,NEIL3,NEIL2,MBD4 |
| 1.882e-02 | -3.97 | SHAFFER_IRF4_TARGETS_IN_MYELOMA_VS_MATURE_B_LYMPHOCYTE | MSigDB lists | SHAFFER_IRF4_TARGETS_IN_MYELOMA_VS_MATURE_B_LYMPHOCYTE | 98 | 23 | 17377 | 2626 |
CCNC,TIMP2,TNFAIP3,PPP1R2,TM9SF4,GNG7,UCK2,LDHA,KRAS,CYCS,VDAC1,PABPC4,DNAJB9,CFLAR,SSR1,SLC31A1,DNAJC10,SUB1,EIF2S2,UAP1,GRSF1,NFIL3,AHCY |
| 1.892e-02 | -3.97 | phyllodes_tumour | COSMIC cancer mutations | phyllodes_tumour | 24 | 8 | 17385 | 2587 |
FGFR3,RB1,NRAS,BRCA1,MEN1,SMAD4,HRAS,CDKN2A |
| 1.892e-02 | -3.97 | breast-other-phyllodes_tumour | COSMIC cancer mutations | breast-other-phyllodes_tumour | 24 | 8 | 17385 | 2587 |
FGFR3,RB1,NRAS,BRCA1,MEN1,SMAD4,HRAS,CDKN2A |
| 1.894e-02 | -3.97 | Wnt signaling pathway | biological process | GO:0016055 | 351 | 68 | 17256 | 2622 |
ZBED3,CYLD,RAC1,XIAP,CSNK2A1,CUL1,PSMA6,PSMD1,CDC42,AP2B1,DVL2,USP34,CELSR2,RBX1,PSMA8,CUL3,PSMB7,FRAT2,LRP5,SOX4,PSMB9,CXXC4,PAF1,HHEX,RPS27A,PSMD8,PSMD3,AXIN1,STK11,DVL1,SMURF1,ARRB2,AP2S1,PSMC1,CSNK1D,AGO2,PRKAA1,NKD2,ZNRF3,PPP3CB,CSNK1A1,PSMD9,PSEN1,CDC73,SCYL2,FZD6,PSMD2,PTEN,AXIN2,BRD7,CTR9,ZRANB1,CSNK1G3,PPP3CA,CSNK1G2,RHOA,LDB1,PSMA1,RTF1,MACF1,MARK2,PSMB3,PSMC4,CSNK1G1,WNT5B,PPP3R1,DDB1,VPS29 |
| 1.894e-02 | -3.97 | cell-cell signaling by wnt | biological process | GO:0198738 | 351 | 68 | 17256 | 2622 |
ZBED3,CYLD,RAC1,XIAP,CSNK2A1,CUL1,PSMA6,PSMD1,CDC42,AP2B1,DVL2,USP34,CELSR2,RBX1,PSMA8,CUL3,PSMB7,FRAT2,LRP5,SOX4,PSMB9,PAF1,CXXC4,HHEX,RPS27A,PSMD8,PSMD3,AXIN1,STK11,DVL1,SMURF1,ARRB2,AP2S1,PSMC1,CSNK1D,AGO2,PRKAA1,NKD2,ZNRF3,PPP3CB,CSNK1A1,PSEN1,PSMD9,SCYL2,CDC73,FZD6,PSMD2,PTEN,AXIN2,CTR9,BRD7,ZRANB1,CSNK1G3,PPP3CA,CSNK1G2,RHOA,LDB1,PSMA1,RTF1,MACF1,MARK2,PSMB3,PSMC4,CSNK1G1,WNT5B,PPP3R1,VPS29,DDB1 |
| 1.902e-02 | -3.96 | Class I PI3K signaling events mediated by Akt | Pathway Interaction DB | pi3kciaktpathway | 34 | 12 | 2226 | 426 |
PDPK1,KPNA1,PRKDC,RAF1,AKT2,CDKN1B,YWHAZ,MAP3K5,YWHAH,PRKACA,FOXO3,MLST8 |
| 1.904e-02 | -3.96 | TRAK2 (trafficking kinesin protein 2) | protein interactions | 66008 | 35 | 11 | 17029 | 2761 |
PLK1,KIF5B,FOXK1,PRKAA1,TRAK1,FAM83D,OGT,KLC1,RHOT1,MTX2,SNAPIN |
| 1.904e-02 | -3.96 | WDR3 (WD repeat domain 3) | protein interactions | 10885 | 35 | 11 | 17029 | 2761 |
RPA2,ZNF512,TBL3,ZNF746,GTPBP4,RBM4,IFI16,PNO1,USP36,BYSL,RPA1 |
| 1.904e-02 | -3.96 | DACH1 (dachshund family transcription factor 1) | protein interactions | 1602 | 35 | 11 | 17029 | 2761 |
ZCCHC10,EWSR1,SCOC,PPIG,EYA1,C1orf35,CREB1,UBE2I,AHCYL1,RNF14,SMAD4 |
| 1.904e-02 | -3.96 | CHAMP1 (chromosome alignment maintaining phosphoprotein 1) | protein interactions | 283489 | 35 | 11 | 17029 | 2761 |
ZNF428,CDKN2AIPNL,PIN1,SUMO2,NFATC2,TTC4,HDGFL2,MAD2L2,DEF6,CBX3,TERF2 |
| 1.904e-02 | -3.96 | PTGS2 (prostaglandin-endoperoxide synthase 2) | protein interactions | 5743 | 35 | 11 | 17029 | 2761 |
DERL1,NUCB1,PSMD1,HSPA4,RBX1,ELMO1,CUL1,USP22,APP,MAPK3,ABHD16A |
| 1.904e-02 | -3.96 | ASB9 (ankyrin repeat and SOCS box containing 9) | protein interactions | 140462 | 35 | 11 | 17029 | 2761 |
HSPA4,H2AFZ,ELOA,LDHA,AKR1B1,ANXA5,ACTB,RAB1A,H3F3A,PGAM1,PRPSAP1 |
| 1.904e-02 | -3.96 | FLCN (folliculin) | protein interactions | 201163 | 35 | 11 | 17029 | 2761 |
CCT2,AHSA1,SF3B1,FNIP2,PTGES3,PPP5C,MAP1LC3B,CCT8,APP,HSPA1B,CDC37 |
| 1.904e-02 | -3.96 | NDUFAF5 (NADH:ubiquinone oxidoreductase complex assembly factor 5) | protein interactions | 79133 | 35 | 11 | 17029 | 2761 |
BOLA3,NSMF,XRCC2,PPA2,MRPL43,METTL2A,STARD7,MRPL21,ECH1,RAD51D,NDUFS7 |
| 1.904e-02 | -3.96 | Cep78 (centrosomal protein 78) | protein interactions | 208518 | 35 | 11 | 17029 | 2761 |
NAP1L1,PCM1,HUWE1,CIC,FOPNL,NSUN2,NAP1L4,PLEC,MVP,H3F3A,MBD4 |
| 1.904e-02 | -3.96 | Kif19a (kinesin family member 19A) | protein interactions | 286942 | 35 | 11 | 17029 | 2761 |
SRP72,CYFIP1,GOLIM4,MAGT1,NDUFB6,ZMYND11,CENPF,HEXB,DNM2,CFAP20,ESPL1 |
| 1.904e-02 | -3.96 | NAPRT (nicotinate phosphoribosyltransferase) | protein interactions | 93100 | 35 | 11 | 17029 | 2761 |
SEC31A,CCDC57,IDE,ACLY,ARMT1,NENF,TCEA1,EIF2A,PPP5C,LTA4H,IGBP1 |
| 1.904e-02 | -3.96 | MTPN (myotrophin) | protein interactions | 136319 | 35 | 11 | 17029 | 2761 |
PTPN11,PIP4K2C,CNTROB,MCM2,RBBP4,RAB1A,SASS6,MAPK1,PIP4K2A,NPLOC4,DCTN1 |
| 1.904e-02 | -3.96 | SLC1A1 (solute carrier family 1 member 1) | protein interactions | 6505 | 35 | 11 | 17029 | 2761 |
RAB8A,EWSR1,GOLGA7,MICU2,PXMP2,APOOL,CHPT1,APP,RNF5,CD320,LMNA |
| 1.904e-02 | -3.96 | IWS1 (IWS1, SUPT6H interacting protein) | protein interactions | 55677 | 35 | 11 | 17029 | 2761 |
SDHB,CTDP1,CSNK2A1,CTR9,TCEA1,RUVBL2,PIP4K2A,DHX15,WDR48,POLR2A,SUPT16H |
| 1.904e-02 | -3.96 | WDR44 (WD repeat domain 44) | protein interactions | 54521 | 35 | 11 | 17029 | 2761 |
OSBPL11,RAB11B,TRIP10,DHX16,KBTBD7,CSNK2A1,PRPF39,FBXL19,RAB11A,ACSF2,PDXDC1 |
| 1.904e-02 | -3.96 | TONSL (tonsoku like, DNA repair protein) | protein interactions | 4796 | 35 | 11 | 17029 | 2761 |
EWSR1,TONSL,MCM5,H2AFX,BRCA1,MCM2,SLC25A5,ASF1B,SUPT16H,XRCC5,SSRP1 |
| 1.906e-02 | -3.96 | CIRBP (cold inducible RNA binding protein) | protein interactions | 1153 | 77 | 20 | 17029 | 2761 |
PLK1,CUL3,CUL1,ATXN1,CSNK2A1,ORC1,SF3A2,APP,SNRPA,CNOT3,PAPOLA,CAND1,GTF2F1,PRNP,RBMX,AHSA1,KHSRP,NAA20,CCNB2,SMURF1 |
| 1.908e-02 | -3.96 | positive regulation of histone acetylation | biological process | GO:0035066 | 28 | 9 | 17256 | 2622 |
TGFB1,KAT2A,KAT7,WBP2,BRD7,BRCA1,RUVBL2,SMAD4,MAPK3 |
| 1.908e-02 | -3.96 | Golgi to plasma membrane protein transport | biological process | GO:0043001 | 28 | 9 | 17256 | 2622 |
GCC2,GOLGA4,GOLPH3L,SYS1,GOLGA7,NSF,ANK3,MACF1,OPTN |
| 1.908e-02 | -3.96 | regulation of actin nucleation | biological process | GO:0051125 | 28 | 9 | 17256 | 2622 |
CYFIP1,WAS,GMFG,GMFB,ARFIP2,WIPF1,NCKAP1,CORO1A,ARF1 |
| 1.909e-02 | -3.96 | Cytosolic tRNA aminoacylation | REACTOME pathways | R-HSA-379716 | 26 | 9 | 10287 | 1696 |
FARSA,KARS,EPRS,LARS,IARS,HARS,QARS,PPA1,TARS |
| 1.909e-02 | -3.96 | N-glycan antennae elongation in the medial/trans-Golgi | REACTOME pathways | R-HSA-975576 | 26 | 9 | 10287 | 1696 |
MAN2A2,B4GALT5,FUT8,B4GALT1,B4GALT3,ST8SIA2,B4GALT4,MGAT5,B4GALT2 |
| 1.909e-02 | -3.96 | HAUS1 (HAUS augmin like complex subunit 1) | protein interactions | 115106 | 127 | 30 | 17029 | 2761 |
CCDC57,MCM10,SEPT9,DCTN2,NUP54,VTI1A,ARFIP2,HAUS4,HAUS2,SPAG5,HNRNPA2B1,PCM1,GOLGA2,EIF4A3,RALB,CENPJ,ODF2,PIK3R2,CEP55,NUP62,ACTB,CEP63,SASS6,CCDC59,MYL12B,PABPC1,FGFR1OP2,POC5,TUBB,HNRNPM |
| 1.910e-02 | -3.96 | GO_CERAMIDE_METABOLIC_PROCESS | MSigDB lists | GO_CERAMIDE_METABOLIC_PROCESS | 72 | 18 | 17377 | 2626 |
GALC,HEXB,CERK,GBA,ASAH1,NEU1,PPP2CA,ITGB8,ORMDL2,CERS6,ST3GAL2,SAMD8,SMPD4,CLN3,ST8SIA2,CLN6,HTRA2,GM2A |
| 1.911e-02 | -3.96 | ACACTAC,MIR-142-3P | MSigDB lists | ACACTAC,MIR-142-3P | 125 | 28 | 17377 | 2626 |
MOB4,STAU1,KAT7,ANK3,TAOK1,RAC1,BCLAF1,AKT1S1,LRRC1,DCUN1D4,RLF,STAM,EML4,GNB2,FBXO3,FKBP1A,ATP2A2,INPP5A,TAB2,ADCY9,ARNTL,AFF1,TARDBP,MBD6,TFG,BRWD3,TIPARP,CPEB2 |
| 1.912e-02 | -3.96 | SET | prosite domains | PS50280 | 51 | 13 | 12060 | 1670 |
ASH1L,KMT5C,SUV39H2,KMT2E,KMT5A,SETD3,PRDM4,EHMT1,KMT2B,NSD3,EZH1,KMT2C,PRDM11 |
| 1.914e-02 | -3.96 | ETSDOMAIN | prints domains | PR00454 | 28 | 7 | 4652 | 473 |
ETS2,ELK1,ETV3,ERF,ETS1,GABPA,ETV6 |
| 1.914e-02 | -3.96 | SAR1GTPBP | prints domains | PR00328 | 28 | 7 | 4652 | 473 |
ARF1,SAR1A,ARL5B,ARL17A,ARF5,ARL5A,ARF4 |
| 1.914e-02 | -3.96 | REVINTRACTNG | prints domains | PR00405 | 28 | 7 | 4652 | 473 |
SMAP1,ASAP2,AGFG1,GIT2,SMAP2,ARAP1,ACAP1 |
| 1.917e-02 | -3.95 | SUCCINYL_COA_LIG_2 | prosite domains | PS00399 | 2 | 2 | 12060 | 1670 |
SUCLG1,ACLY |
| 1.917e-02 | -3.95 | XTBD | prosite domains | PS51827 | 2 | 2 | 12060 | 1670 |
CDKN2AIP,CDKN2AIPNL |
| 1.917e-02 | -3.95 | PITH | prosite domains | PS51532 | 2 | 2 | 12060 | 1670 |
TXNL1,PITHD1 |
| 1.917e-02 | -3.95 | MDH | prosite domains | PS00068 | 2 | 2 | 12060 | 1670 |
MDH1,MDH2 |
| 1.917e-02 | -3.95 | GALACTOKINASE | prosite domains | PS00106 | 2 | 2 | 12060 | 1670 |
GALK1,GALK2 |
| 1.917e-02 | -3.95 | B12_BINDING | prosite domains | PS51332 | 2 | 2 | 12060 | 1670 |
MUT,MTR |
| 1.917e-02 | -3.95 | PPASE | prosite domains | PS00387 | 2 | 2 | 12060 | 1670 |
PPA1,PPA2 |
| 1.917e-02 | -3.95 | TATD_3 | prosite domains | PS01091 | 2 | 2 | 12060 | 1670 |
TATDN1,TATDN2 |
| 1.917e-02 | -3.95 | ZF_FPG_2 | prosite domains | PS51066 | 2 | 2 | 12060 | 1670 |
NEIL3,NEIL2 |
| 1.917e-02 | -3.95 | RIBOSOMAL_S2_1 | prosite domains | PS00962 | 2 | 2 | 12060 | 1670 |
MRPS2,RPSA |
| 1.917e-02 | -3.95 | MIRO | prosite domains | PS51423 | 2 | 2 | 12060 | 1670 |
RHOT1,RHOT2 |
| 1.917e-02 | -3.95 | SUCCINYL_COA_LIG_1 | prosite domains | PS01216 | 2 | 2 | 12060 | 1670 |
SUCLG1,ACLY |
| 1.918e-02 | -3.95 | histone binding | molecular function | GO:0042393 | 194 | 41 | 17224 | 2647 |
PWWP2A,DNAJC2,HJURP,MPHOSPH8,KMT2E,KDM4A,SUZ12,WDTC1,SMARCA4,WDR5,CHD1,NOC2L,ANP32A,BRD7,SAP30L,CARM1,MSH6,BRD4,NASP,BAZ2A,ZMYND11,KDM1B,MCM2,ASF1B,PHF6,SUPT16H,CTSL,BRD2,ATAD2,TONSL,H2AFX,UHRF2,STAT1,BAZ1B,PRMT7,ANP32E,CENPT,RBBP4,BRD9,SGF29,CBX4 |
| 1.919e-02 | -3.95 | Circadian rhythm | KEGG pathways | ko04710 | 31 | 10 | 7161 | 1149 |
RORB,PRKAB1,RBX1,ARNTL,PRKAA1,CUL1,CRY2,FBXL3,CREB1,CSNK1D |
| 1.919e-02 | -3.95 | Circadian rhythm | KEGG pathways | hsa04710 | 31 | 10 | 7161 | 1149 |
RORB,PRKAB1,RBX1,ARNTL,PRKAA1,CUL1,CRY2,FBXL3,CREB1,CSNK1D |
| 1.919e-02 | -3.95 | GSE7509_UNSTIM_VS_FCGRIIB_STIM_MONOCYTE_UP | MSigDB lists | GSE7509_UNSTIM_VS_FCGRIIB_STIM_MONOCYTE_UP | 158 | 34 | 17377 | 2626 |
SRM,KARS,SARNP,CASP6,RAB11B,MRPL39,EIF3D,SUMO2,CIB1,TMEM109,AGPAT3,SDF2L1,QSOX2,RHBDD1,SEC11A,EFTUD2,EXOSC1,PPP6C,CLDND1,GTF2H2,LRRC59,FDFT1,PGAP2,NAGPA,TUFM,LLPH,EIF2A,OGFR,HAGH,EIF3G,RWDD4,PPP1R11,AP1S1,SSRP1 |
| 1.919e-02 | -3.95 | GSE25147_UNSTIM_VS_HELIOBACTER_PYLORI_LPS_STIM_MKN45_CELL_UP | MSigDB lists | GSE25147_UNSTIM_VS_HELIOBACTER_PYLORI_LPS_STIM_MKN45_CELL_UP | 158 | 34 | 17377 | 2626 |
ZBED3,ANK3,CHIC2,COX4I1,EXT2,RPL23A,NUDT19,ERH,RAB21,PA2G4,PSMD1,ZNRF2,SSBP3,MEA1,MRPL40,MRPL48,METTL9,PDCL3,ZFP64,AKT2,DENND4C,DENND1B,RNPS1,LLPH,UBE2V1,CHMP2B,PRDX1,RPSA,CHCHD3,ATP6V1D,PDLIM1,RWDD4,FAM126A,HEXA |
| 1.919e-02 | -3.95 | V$MYOD_Q6_01 | MSigDB lists | V$MYOD_Q6_01 | 237 | 48 | 17377 | 2626 |
PRPF38B,CYLD,GADD45G,WDTC1,ACAP1,PLAGL2,KLHL18,RRAGC,TMEM165,STMN1,POFUT1,MYL6B,FBRS,KIF5B,DST,TFAP4,JAZF1,SLC44A1,AXIN2,CTR9,ZNF710,GPD1L,CFL1,SPTAN1,CPNE1,PPIF,USO1,POLR3GL,LNX2,ARHGEF12,WDR81,PLEC,MTX1,DCLRE1C,CADM1,PCGF1,ARL5B,TAZ,HMGN2,GNAS,UBTF,ELMO1,SH3GLB2,IMPDH1,FAM126A,MBD6,ZMAT3,ATXN7L2 |
| 1.923e-02 | -3.95 | PHF6 (PHD finger protein 6) | protein interactions | 84295 | 44 | 13 | 17029 | 2761 |
HNRNPA2B1,LYAR,SNRNP200,H2AFZ,CHD3,HNRNPH3,CUL3,ORC1,FBL,RBBP4,PCBP2,SRPK2,CAND1 |
| 1.923e-02 | -3.95 | RAD52 (RAD52 homolog, DNA repair protein) | protein interactions | 5893 | 44 | 13 | 17029 | 2761 |
RPA2,HSPA4,RPS10,YWHAZ,ACTB,AURKB,MCM2,UBE2I,PRDX1,EEF1D,POLR2A,RPA1,LDHB |
| 1.923e-02 | -3.95 | CD83 (CD83 molecule) | protein interactions | 9308 | 44 | 13 | 17029 | 2761 |
RHOBTB3,TSC2,THADA,C1orf112,BTAF1,ZDHHC13,USP32,CERK,TBRG4,TNPO2,KRAS,CD320,CIP2A |
| 1.923e-02 | -3.95 | CALM2 (calmodulin 2) | protein interactions | 805 | 44 | 13 | 17029 | 2761 |
UNK,CEP104,CCP110,CENPJ,CAMKMT,H2AFX,CUL3,CUL1,STK11,PPP3CB,ADRB2,MCM2,RPSA |
| 1.923e-02 | -3.95 | PSMG1 (proteasome assembly chaperone 1) | protein interactions | 8624 | 44 | 13 | 17029 | 2761 |
PSMA6,PSMB7,CAPZA1,PSMA1,PSMG1,CUL1,BRCA1,CAPZA2,POMP,EHD4,PSMB9,PSMB3,PFKP |
| 1.923e-02 | -3.95 | ESYT1 (extended synaptotagmin 1) | protein interactions | 23344 | 44 | 13 | 17029 | 2761 |
DERL1,RPA2,MDM2,GBA,TMEM216,YIF1B,CDK2,NCDN,TMX1,ESYT2,RPA1,RDH11,EVC2 |
| 1.923e-02 | -3.95 | ZNF622 (zinc finger protein 622) | protein interactions | 90441 | 44 | 13 | 17029 | 2761 |
STAU1,PPP1R2,EFTUD2,MYBL2,C1orf35,EBNA1BP2,BRIX1,NMD3,LSG1,FTSJ3,APP,DCTN1,KRR1 |
| 1.923e-02 | -3.95 | LSM5 (LSM5 homolog, U6 small nuclear RNA and mRNA degradation associated) | protein interactions | 23658 | 44 | 13 | 17029 | 2761 |
SART1,MIF4GD,RBM42,LSM6,DHX16,RMI2,LSM8,KRAS,PRPF4,PRPF3,PATL1,DDX23,ZNF511 |
| 1.923e-02 | -3.95 | BASP1 (brain abundant membrane attached signal protein 1) | protein interactions | 10409 | 44 | 13 | 17029 | 2761 |
PLAA,HMGN5,UBXN1,EFTUD2,MYO18A,HNRNPF,MYH9,ATXN1,ATP5F1A,ANLN,ATF2,WDR48,RAD23A |
| 1.923e-02 | -3.95 | SCCPDH (saccharopine dehydrogenase (putative)) | protein interactions | 51097 | 44 | 13 | 17029 | 2761 |
RPN1,RAB4A,KBTBD7,ENSA,NDUFA4,MDH1,PPP6R2,MIEN1,BZW2,ATP6V0D1,PAIP2,TMEM160,USP13 |
| 1.926e-02 | -3.95 | GO_MRNA_3_UTR_BINDING | MSigDB lists | GO_MRNA_3_UTR_BINDING | 47 | 13 | 17377 | 2626 |
HNRNPA2B1,SYNCRIP,HNRNPR,CIRBP,RNPS1,KHSRP,TARDBP,SECISBP2,FXR1,PARN,CPEB2,RBM4,RBM38 |
| 1.926e-02 | -3.95 | ATCMNTCCGY_UNKNOWN | MSigDB lists | ATCMNTCCGY_UNKNOWN | 47 | 13 | 17377 | 2626 |
UBE2D3,HIVEP3,TCF12,TSC1,ATAD2,RBL1,MIER1,WBP2,NUP62,MBD6,SNRNP70,KDM3A,GNB2 |
| 1.926e-02 | -3.95 | YTTCCNNNGGAMR_UNKNOWN | MSigDB lists | YTTCCNNNGGAMR_UNKNOWN | 47 | 13 | 17377 | 2626 |
PPME1,SSBP3,TAOK1,MYO18A,CAPZA1,TUFM,DNAJC24,DNAJB1,AP1B1,ARID4A,IPO4,PRPF18,C1orf122 |
| 1.926e-02 | -3.95 | NADERI_BREAST_CANCER_PROGNOSIS_UP | MSigDB lists | NADERI_BREAST_CANCER_PROGNOSIS_UP | 47 | 13 | 17377 | 2626 |
PSMD2,ASPM,PTTG1,CDCA5,CEP55,MYBL2,CDCA8,TIMELESS,SMARCA4,RACGAP1,SPAG5,FADD,EBP |
| 1.928e-02 | -3.95 | GO_NON_CANONICAL_WNT_SIGNALING_PATHWAY | MSigDB lists | GO_NON_CANONICAL_WNT_SIGNALING_PATHWAY | 136 | 30 | 17377 | 2626 |
PPP3CA,RHOA,CELSR2,PSMA8,RAC1,PSMB7,PSMA1,PPP3CB,ZNRF3,PSMB9,PSMD9,PSMB3,FZD6,PSMC4,CALM2,PSMD2,PSMA6,PSMD1,CDC42,RPS27A,PSMD8,PSMD3,PPP3R1,AP2B1,DVL1,SMURF1,ARRB2,PSMC1,AP2S1,DVL2 |
| 1.930e-02 | -3.95 | insulin receptor signaling pathway | biological process | GO:0008286 | 82 | 20 | 17256 | 2622 |
AKT2,ATP6V0A1,ATP6V1B2,AP3S1,APPL1,SOCS7,PTPN2,ATP6V0B,PDK2,ATP6V1D,IDE,SHC1,PIK3R2,ATP6V0A2,ATP6V0C,ATP6V1C1,C2CD5,ATP6V0E1,ATP6V0D1,ATP6V1G1 |
| 1.931e-02 | -3.95 | GSE360_CTRL_VS_B_MALAYI_LOW_DOSE_MAC_UP | MSigDB lists | GSE360_CTRL_VS_B_MALAYI_LOW_DOSE_MAC_UP | 186 | 39 | 17377 | 2626 |
PPIB,GLT8D1,MPHOSPH8,UGP2,HLA-E,SRGN,ENSA,ASAH1,PTP4A3,BTN3A1,B4GALT1,MYL6B,SP100,EIF4A3,MCM5,CAPZA1,ZDHHC18,DDX28,BTG2,RABIF,KRAS,UTP3,MTX1,UBE4B,PCGF1,LY6E,ARPC1A,HMGN2,MYO1F,PAF1,ADSS,PLD3,POLR2J,LTBP4,CSK,PSMD3,ITGB1,SSNA1,DDX52 |
| 1.931e-02 | -3.95 | GSE17721_PAM3CSK4_VS_CPG_16H_BMDC_UP | MSigDB lists | GSE17721_PAM3CSK4_VS_CPG_16H_BMDC_UP | 186 | 39 | 17377 | 2626 |
SRM,RMND5A,EWSR1,NOP2,RPS6KA1,SHPRH,GSPT2,TOP2B,ARGLU1,ABHD14A,CPNE3,RNF103,XPR1,MAN1A1,C14orf119,ADD3,ATP2A2,IMPAD1,SLC44A1,ATP6V0D1,RPL22L1,USP34,FDFT1,SRSF11,FAM118B,EID1,RAB7A,EMP3,TMEM147,UBE4B,BTBD1,XRCC5,EIF3K,HSPB11,ZHX1,PARG,COX8A,SAMD8,RTN3 |
| 1.931e-02 | -3.95 | GSE3039_ALPHABETA_CD8_TCELL_VS_B1_BCELL_UP | MSigDB lists | GSE3039_ALPHABETA_CD8_TCELL_VS_B1_BCELL_UP | 186 | 39 | 17377 | 2626 |
SHPRH,RAF1,FAM129A,TRIM11,ANKH,XIAP,AP3M2,STARD7,CDK13,MAN2B1,CCNL2,SNN,DOCK11,RGS2,RAPGEF6,BZW2,MXD1,C2orf68,NAPG,GATC,CYB5R1,ZNF770,VPS13B,RPL35,AATF,PBXIP1,MIER1,KIAA0930,DIDO1,CYFIP2,STX16,SH3BP5,NSA2,FNTA,TBPL1,OGT,AKNA,MAP3K5,MYO9A |
| 1.931e-02 | -3.95 | GSE17721_POLYIC_VS_CPG_12H_BMDC_UP | MSigDB lists | GSE17721_POLYIC_VS_CPG_12H_BMDC_UP | 186 | 39 | 17377 | 2626 |
FAM208B,FEZ2,H2AFZ,TMEM184B,TSC22D3,RHOC,DAP,UROD,PTTG1,PXMP2,TBC1D13,TAF6L,CCNL2,SLC12A9,PTEN,ARF5,SLC44A1,BRI3,GLTP,APOOL,NSUN4,CDC37,KDM3B,GUK1,CSRP1,SNX2,THNSL1,PRMT2,KLF6,RAB22A,ARF4,FBXO21,RBM25,TXNDC16,CLK3,ERGIC3,NFIL3,NCOA1,TOB1 |
| 1.931e-02 | -3.95 | GSE14769_UNSTIM_VS_20MIN_LPS_BMDM_DN | MSigDB lists | GSE14769_UNSTIM_VS_20MIN_LPS_BMDM_DN | 186 | 39 | 17377 | 2626 |
MBD1,IER2,GOLIM4,CYLD,MPHOSPH8,GORASP1,GADD45G,ABCB10,GMCL1,ORC1,RGS1,LRRC14,KRI1,LYAR,VMP1,DCP1A,NUP153,GPD1L,DNMT1,RYBP,CYFIP1,BTG2,ACSL3,ELP4,MAP4K3,BRCA1,ANLN,NEU1,TRIM47,HHEX,ZNF777,BRD2,DHX16,MRFAP1L1,BEND3,ZNF830,TRAF5,PTDSS1,RNF139 |
| 1.931e-02 | -3.95 | GSE21927_SPLEEN_C57BL6_VS_4T1_TUMOR_BALBC_MONOCYTES_DN | MSigDB lists | GSE21927_SPLEEN_C57BL6_VS_4T1_TUMOR_BALBC_MONOCYTES_DN | 186 | 39 | 17377 | 2626 |
DDX58,UBE2D3,NDUFV2,PARP12,MRPL42,HLA-E,UBE2Q1,GSTK1,RAB8A,SP100,IARS,ATG3,LPIN2,ZCCHC2,PPCDC,DCP1A,BRD7,TRIM14,MORC3,EIF5A,HMGN1,TRAFD1,MKLN1,LAP3,DRAP1,TMEM126B,RNF25,PARP4,MCL1,DNAJA1,LY6E,ISG15,HMGN2,TRIM26,MID1IP1,PML,EHD4,MRPL13,IFI16 |
| 1.931e-02 | -3.95 | GSE5589_UNSTIM_VS_180MIN_LPS_AND_IL10_STIM_MACROPHAGE_DN | MSigDB lists | GSE5589_UNSTIM_VS_180MIN_LPS_AND_IL10_STIM_MACROPHAGE_DN | 186 | 39 | 17377 | 2626 |
CYLD,ZNF445,ANXA6,DEPDC1,ZCCHC8,SEC61G,RRAGC,B4GALT1,WDR5,UBE2I,SAFB2,GGPS1,CRLF3,COMMD8,DTL,PHF14,SLC44A1,PPP1R12C,ZDHHC13,SLC27A4,KIF22,TAP2,CNPY3,PPA1,SRSF11,TRAFD1,MLEC,ERLIN1,SLBP,PBRM1,MTR,TSR2,NEU1,SGSH,PFDN4,SNAP23,HAGHL,RNASEL,LRP8 |
| 1.941e-02 | -3.94 | FONTAINE_FOLLICULAR_THYROID_ADENOMA_UP | MSigDB lists | FONTAINE_FOLLICULAR_THYROID_ADENOMA_UP | 67 | 17 | 17377 | 2626 |
AMPD2,ZNF76,PBXIP1,DAP,LRP5,NDUFA7,TOMM40,CRLF3,DDX56,PDLIM1,KIF18B,RBM25,OAZ2,GLG1,CABIN1,TSPAN5,USP13 |
| 1.941e-02 | -3.94 | Pre-NOTCH Processing in Golgi | REACTOME pathways | R-HSA-1912420 | 18 | 7 | 10287 | 1696 |
B4GALT1,RAB6A,NOTCH2,ATP2A2,TMED2,SEL1L,MFNG |
| 1.943e-02 | -3.94 | pyrimidine-containing compound biosynthetic process | biological process | GO:0072528 | 42 | 12 | 17256 | 2622 |
ERH,TK1,DCK,DUT,UCK2,CTPS1,TBPL1,UPRT,UCK1,DCTD,DHFR2,HDDC2 |
| 1.944e-02 | -3.94 | skin-carcinoma | COSMIC cancer mutations | skin-carcinoma | 38 | 11 | 17385 | 2587 |
GNAS,NRAS,CDC42,NEK6,SF3B1,MAP4K4,KRAS,CHEK2,CDK2,MAP2K2,HRAS |
| 1.944e-02 | -3.94 | soft_tissue-nerve_sheath-malignant_peripheral_nerve_sheath_tumour | COSMIC cancer mutations | soft_tissue-nerve_sheath-malignant_peripheral_nerve_sheath_tumour | 38 | 11 | 17385 | 2587 |
FGFR3,RB1,EWSR1,NRAS,NF1,PTEN,ETV6,KRAS,FUS,HRAS,CDKN2A |
| 1.944e-02 | -3.94 | vertebrae | COSMIC cancer mutations | vertebrae | 68 | 17 | 17385 | 2587 |
GNAS,RB1,NRF1,EWSR1,NRAS,PTEN,TUFM,GORASP2,KRAS,TMEM101,CDC25B,TRIM32,H3F3A,ERI3,EIF4G2,HRAS,CDKN2A |
| 1.946e-02 | -3.94 | transmembrane receptor protein tyrosine kinase signaling pathway | biological process | GO:0007169 | 523 | 97 | 17256 | 2622 |
WASF2,RAB14,REPS2,TSC2,RAF1,RAC1,ACTR3,SIRT2,ATP6V1B2,MAPK14,LYN,STMN1,CPNE3,VAV1,ABL2,PDK2,ATP6V0B,SHC1,CDC42,CD3EAP,PIK3R2,ZFYVE27,AP2B1,TIPARP,ABI1,CDC37,ATP6V1G1,SHOC2,NRAS,PTPN18,POLR2G,POLR2L,NCK1,APH1A,AKT2,HNRNPF,POLR2D,ATP6V0A1,ERBIN,SHCBP1,ZFAND5,ARF4,GIGYF1,SOCS7,IDE,JAK1,RPS27A,ATP6V0C,ACTB,ROCK1,MAPK1,AP2S1,ATP6V0E1,C2CD5,POLR2K,VAV2,SDC2,TIA1,AKT1S1,NCKAP1,APH1B,PSEN1,AP3S1,GTF2F1,PTPN2,FGFR3,NUS1,ARPC5,PTEN,PTPN11,ATP6V0A2,MVP,STAT3,ATP6V0D1,HNRNPM,SOCS5,TGFB1,PDPK1,CYFIP1,POLR2I,RHOA,ADAM17,MAPKAPK3,KRAS,ADRB2,CYFIP2,ARPC1A,APPL1,POLR2A,MAPK3,ATP6V1D,PDCD6,POLR2J,ELMO1,CSK,ATP6V1C1,HRAS |
| 1.947e-02 | -3.94 | BCL6 (B cell CLL/lymphoma 6) | protein interactions | 604 | 117 | 28 | 17029 | 2761 |
USP7,NCOR2,PARP12,FOXM1,RAF1,EHMT1,E2F3,CUL3,OLA1,SMARCA4,NKRF,MBD3,CUTC,IRF4,PRKD3,EIF4ENIF1,KDM2A,SIAH1,CHD3,HDAC7,PIN1,KIF13B,PML,KMT2B,YY1,PIKFYVE,MAPK1,HDAC2 |
| 1.948e-02 | -3.94 | ubiquitin binding | molecular function | GO:0043130 | 71 | 18 | 17224 | 2647 |
TNFAIP3,RAE1,UBXN1,SIRT2,TOLLIP,BIRC2,WDR48,NPLOC4,USP5,UBXN2A,PLAA,UBXN2B,FBXO7,NSFL1C,NUP62,TRIM32,FAF1,USP13 |
| 1.950e-02 | -3.94 | GO_ENDOCYTOSIS | MSigDB lists | GO_ENDOCYTOSIS | 460 | 86 | 17377 | 2626 |
WASF2,RAB14,TSC2,TRIP10,RAC1,ACTR3,MYH9,CDC42SE2,BCL2L1,BECN1,LYN,RUFY1,SYNRG,APP,CDK5,VAV1,CDC42,DPYSL2,PIK3R2,DNM2,AP2B1,CORO1A,MARCH2,CLTB,PDIA6,ABI1,SNX8,NCK1,PPT1,RAB7A,WIPF1,EZR,LRP5,RAB1A,RAB22A,NECAP2,WAS,LIMK1,CORO1C,ITGB1,AP1S1,ACTB,SCARB1,CLN3,ARRB2,MAPK1,AP2S1,LRP8,ABCA1,CSNK1D,ANXA11,HSPH1,VAV2,EPN1,JMJD6,NCKAP1,CSNK1A1,SCYL2,TFRC,PIP5K1C,SNX18,RINL,ARPC5,PIKFYVE,LDLRAD3,GTF2H2,LRSAM1,CSNK1G3,CSNK1G2,CYFIP1,MAPKAPK3,SNX2,EIF2AK1,ADRB2,CYFIP2,ARPC1A,PICALM,MAPK3,ELMO1,CSNK1G1,USP20,LY75,EHD4,CD81,HRAS,ESYT2 |
| 1.952e-02 | -3.94 | negative regulation of intracellular signal transduction | biological process | GO:1902532 | 541 | 100 | 17256 | 2622 |
ASH1L,GGNBP2,CYLD,TSC2,IVNS1ABP,FOXM1,NF1,UBR2,BCL2L1,LYN,STMN1,DUSP22,PARK7,EPM2A,PRNP,CALM2,DLG5,RRN3,MDM2,SH3BP1,PIN1,PIK3R2,NOC2L,SOCS6,SRI,GPD1L,HTRA2,CHP1,PPIF,PGAP2,CPNE1,TIMP2,VHL,PBK,CUL3,VDAC2,EZR,MCL1,ERBIN,DNAJA1,EIF3A,OPTN,SOCS7,PPP2CA,STK38,ARNTL,SOCS4,ITGB1,STAT1,STK11,TRIM32,CLU,CCDC125,ARRB2,SMAD4,PDCD4,MIF,BCL2L12,HSPH1,PRKAA1,CIB1,AKT1S1,RGS2,NPLOC4,PTPN2,FKBP1A,PTEN,HDAC7,TANK,ARHGEF2,BCL2,PIK3IP1,GNAI2,SOCS5,RHOA,TNFAIP3,ZMYND11,GBA,RFFL,USP10,SYVN1,OTUD3,MEN1,PTTG1IP,PDE3B,MFN2,LEMD2,TMEM127,MBIP,TSC1,HGS,PDCD6,GPS2,DUSP3,CSK,QARS,NUP62,PKD2,IGBP1,HIPK3 |
| 1.953e-02 | -3.94 | ATAAGCT,MIR-21 | MSigDB lists | ATAAGCT,MIR-21 | 109 | 25 | 17377 | 2626 |
UBE2D3,RMND5A,PPP3CA,PSRC1,MRPL9,CREBL2,ARGLU1,UBE4A,ARID1A,PBRM1,PCBP1,RAB11A,RNF103,RHOB,KRIT1,RNFT1,ZNF367,PHF14,SRSF3,GLCCI1,STAT3,CBX4,PDCD4,PCBP2,FUBP1 |
| 1.953e-02 | -3.94 | SMIRNOV_RESPONSE_TO_IR_6HR_DN | MSigDB lists | SMIRNOV_RESPONSE_TO_IR_6HR_DN | 109 | 25 | 17377 | 2626 |
PLK1,IER2,PSRC1,DEPDC1,ASPM,CENPF,TPX2,CDCA3,ACAP1,C5orf30,KIF23,GGA2,CCNB1,RGS2,KDM3A,KLF6,RGS1,HHEX,SLC19A1,KIF14,LPCAT4,GEMIN4,UBE2C,TRAF5,EGLN1 |
| 1.955e-02 | -3.93 | Sec24c (Sec24 related gene family, member C (S. cerevisiae)) | protein interactions | 218811 | 58 | 16 | 17029 | 2761 |
USO1,PKP4,SLC35B2,ERBIN,CSNK1A1,SEC16A,GOSR1,PICALM,XPR1,SEC31A,SEC23IP,GOLGA2,HUWE1,AP2B1,GTSE1,CLTB |
| 1.955e-02 | -3.93 | SEPT9 (septin 9) | protein interactions | 10801 | 58 | 16 | 17029 | 2761 |
NDUFV2,COPA,SUCLG1,TOR1AIP1,MRPL12,BRCA1,SEPT7,ANLN,APP,SEPT1,DDA1,MSH2,SUCLG2,SEPT11,STK11,CDC5L |
| 1.955e-02 | -3.93 | MELK (maternal embryonic leucine zipper kinase) | protein interactions | 9833 | 58 | 16 | 17029 | 2761 |
FAM53C,DENND4C,SF3B1,BABAM1,RAB3IP,USP21,GIGYF1,RTKN,ZBTB21,FAM110A,KIF13B,PPP1R8,CBWD1,CDC25B,CDC5L,MLST8 |
| 1.955e-02 | -3.93 | P2RY12 (purinergic receptor P2Y12) | protein interactions | 64805 | 58 | 16 | 17029 | 2761 |
ACP2,CERS6,GPR89A,MRS2,C19orf25,LMBR1,GEMIN6,TM9SF3,TNPO3,DDX20,GEMIN4,ATP5F1B,GNAI2,CMTM6,TMEM161B,EBP |
| 1.955e-02 | -3.93 | ALOX5 (arachidonate 5-lipoxygenase) | protein interactions | 240 | 58 | 16 | 17029 | 2761 |
KDM3B,MND1,ERMP1,ADSL,PMF1,TRIM65,APP,MTMR3,OSBPL11,CDC16,MTMR4,TPP2,SLAIN1,ACTB,CEP63,DMWD |
| 1.955e-02 | -3.93 | TBC1D4 (TBC1 domain family member 4) | protein interactions | 9882 | 58 | 16 | 17029 | 2761 |
PPP2CA,CCNA2,MPHOSPH8,FOXK1,PIN1,U2SURP,TKT,KIAA1551,YWHAZ,MBOAT1,AURKB,ZMIZ1,FAM208A,CTDSP2,RAB2B,SMC4 |
| 1.955e-02 | -3.93 | MAP3K3 (mitogen-activated protein kinase kinase kinase 3) | protein interactions | 4215 | 58 | 16 | 17029 | 2761 |
PPP2CA,HSPA4,TRAF7,PDRG1,XIAP,YWHAZ,BRCA1,FUS,MAP3K5,PRKACA,GLRX3,YWHAH,SMURF1,BIRC2,MARK2,CDC37 |
| 1.955e-02 | -3.93 | Ferroptosis | KEGG pathways | hsa04216 | 40 | 12 | 7161 | 1149 |
ACSL5,FTL,GCLM,ACSL3,VDAC2,PCBP1,MAP1LC3B,SAT2,PCBP2,TFRC,GPX4,PRNP |
| 1.955e-02 | -3.93 | Ferroptosis | KEGG pathways | ko04216 | 40 | 12 | 7161 | 1149 |
ACSL5,FTL,GCLM,ACSL3,VDAC2,PCBP1,MAP1LC3B,SAT2,PCBP2,TFRC,GPX4,PRNP |
| 1.957e-02 | -3.93 | GNAT_dom | interpro domains | IPR000182 | 24 | 8 | 18492 | 2768 |
NAT14,NAT9,GNPNAT1,NAA20,KAT2A,SAT2,NAA60,NAA50 |
| 1.957e-02 | -3.93 | cation-transporting ATPase activity | molecular function | GO:0019829 | 66 | 17 | 17224 | 2647 |
ATP13A1,ATP2C1,ATP6V0A1,ATP5F1B,ATP6V1B2,ATP6V0B,ATP1A1,ATP2A2,ATP5MC3,ATP13A3,ATP6V0A2,ATP6V0C,ATP5F1A,ATP6V1C1,ATP6V0E1,ATP6V0D1,ATP6V1G1 |
| 1.958e-02 | -3.93 | NPHP1 (nephrocystin 1) | protein interactions | 4867 | 87 | 22 | 17029 | 2761 |
RPAP3,MOB4,UBQLN4,NPHP4,COPA,PRRC2A,TM9SF3,RAB6A,USP22,XPO7,NDUFV1,SEC23IP,PDRG1,RAB35,DNM2,GPATCH1,ECD,TTLL12,CHTOP,IDH3B,TUBB,WDR41 |
| 1.958e-02 | -3.93 | RPAP3 (RNA polymerase II associated protein 3) | protein interactions | 79657 | 87 | 22 | 17029 | 2761 |
RPAP3,TELO2,NPHP4,TM9SF4,POC1A,CUL3,BRCA1,APP,POLR2A,WWP2,CEP104,TSC1,HSPA4,POLR2J,PDRG1,INTS1,EFTUD2,STK11,RUVBL2,TERF1,LUC7L2,CDC37 |
| 1.958e-02 | -3.93 | JAK3 (Janus kinase 3) | protein interactions | 3718 | 87 | 22 | 17029 | 2761 |
CCT2,RNPS1,COX4I1,CCNL2,RAB11A,STAM,CCT8,PTPN2,MAGED2,CAPN2,GNAS,DECR1,NAP1L1,JAK1,DHX16,STAT6,UHRF2,GEMIN6,TNPO3,NAP1L4,STAT3,CD81 |
| 1.958e-02 | -3.93 | GO_REGULATION_OF_DNA_RECOMBINATION | MSigDB lists | GO_REGULATION_OF_DNA_RECOMBINATION | 52 | 14 | 17377 | 2626 |
TERF2IP,TGFB1,RPA2,KPNA1,THOC1,HELB,STAT6,RAD51AP1,MSH2,KPNA2,BLM,MSH6,TERF2,POLQ |
| 1.958e-02 | -3.93 | FLOTHO_PEDIATRIC_ALL_THERAPY_RESPONSE_UP | MSigDB lists | FLOTHO_PEDIATRIC_ALL_THERAPY_RESPONSE_UP | 52 | 14 | 17377 | 2626 |
RAB14,EIF3L,TOMM20,KLF10,RPL17,EIF3D,RPL6,IL12RB1,FAU,RAB1A,STAM,RPS9,RNF139,TMED2 |
| 1.958e-02 | -3.93 | LEE_LIVER_CANCER_MYC_UP | MSigDB lists | LEE_LIVER_CANCER_MYC_UP | 52 | 14 | 17377 | 2626 |
FBXO21,SLC1A4,RPLP2,RALB,RPS14,IDH3A,CDCA3,HTATIP2,RPS24,NUSAP1,LY6E,MAT2A,FDFT1,RPL36 |
| 1.958e-02 | -3.93 | GO_TRNA_MODIFICATION | MSigDB lists | GO_TRNA_MODIFICATION | 52 | 14 | 17377 | 2626 |
METTL1,GTPBP3,CTU2,DUS4L,DUS3L,WDR4,TRMU,NSUN2,TRMT6,UBA5,TYW5,METTL2A,FTSJ1,OSGEPL1 |
| 1.958e-02 | -3.93 | GO_PEPTIDYL_PROLINE_MODIFICATION | MSigDB lists | GO_PEPTIDYL_PROLINE_MODIFICATION | 52 | 14 | 17377 | 2626 |
FKBP1A,PPIF,PPIB,CWC27,PPIG,PIN1,PPIL2,TTC9C,PPIE,FKBP5,PPWD1,FKBP2,FKBP3,EGLN1 |
| 1.958e-02 | -3.93 | GRABARCZYK_BCL11B_TARGETS_DN | MSigDB lists | GRABARCZYK_BCL11B_TARGETS_DN | 52 | 14 | 17377 | 2626 |
PIGN,TIMP2,GOLGA7,C4orf3,SCFD2,FBXW2,PPP3CB,BCL2L1,TFDP2,GSTCD,CNOT6L,PSMD9,GM2A,ASF1B |
| 1.959e-02 | -3.93 | ER Quality Control Compartment (ERQC) | REACTOME pathways | R-HSA-901032 | 22 | 8 | 10287 | 1696 |
RPS27A,MAN1B1,SEL1L,SYVN1,EDEM2,RNF139,RNF5,RNF103 |
| 1.959e-02 | -3.93 | ERK/MAPK targets | REACTOME pathways | R-HSA-198753 | 22 | 8 | 10287 | 1696 |
PPP2CA,MEF2A,ELK1,DUSP3,MAPK1,MAPK14,RPS6KA1,MAPK3 |
| 1.959e-02 | -3.93 | Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters | REACTOME pathways | R-HSA-164938 | 22 | 8 | 10287 | 1696 |
AP2B1,AP1S1,PACS1,ARF1,AP1B1,AP2S1,HLA-A,AP1M1 |
| 1.961e-02 | -3.93 | PLAUR (plasminogen activator, urokinase receptor) | protein interactions | 5329 | 112 | 27 | 17029 | 2761 |
GCLM,WDHD1,TOP2B,NOTCH2,UBQLN2,TAZ,LYN,ARSK,DNAJB9,MAN1A1,PCYOX1L,FASTKD3,MAN2A2,SGSH,TXNDC16,JAK1,TATDN2,IL6ST,NAGLU,ITGB1,XRCC3,CTSA,DHFR2,PSAP,NR2F2,MGAT5,ZNF146 |
| 1.962e-02 | -3.93 | skin | COSMIC cancer mutations | skin | 16759 | 2512 | 17385 | 2587 |
HECA,ZBTB10,ABCC10,HEXB,TGOLN2,CCNL2,FBXO22,EEF2K,THAP4,RAD23B,ATP13A3,DNM2,ZNRD1,FTSJ3,USP34,CCDC57,ERCC1,NRAS,EHMT1,KIF15,HNRNPF,WDHD1,MIER2,DIDO1,MCM2,RAB22A,SMAD2,MID1IP1,RPS27A,MYO18A,OGT,MPV17,COX5A,SMAD1,ZNF75A,ANXA11,SLC25A33,ZNF720,SEC61G,GGA1,MUM1,CCZ1,TRIO,CUTA,RAB23,KCTD17,HAUS4,EIF2AK4,APH1B,PARN,CDC73,MYL6B,ATG4A,TMEM179B,ERV3-1,PDXP,SMC3,GEMIN4,MVP,NUP85,PPP6R1,PABPC1,NSUN4,PPA1,IFRD1,AGGF1,FOXK1,RBM42,GTPBP4,MAP7D1,MRPL16,ELK1,EIF4H,RDH11,MAGED2,KPNA1,ETS2,TYW5,WIPI2,RUFY3,PDLIM5,ACSF2,FAM72D,RHOG,EXOC3,STARD7,C5orf30,VTI1A,INO80E,SLC35B2,RCOR3,LCLAT1,CPNE3,KIAA1147,RBM23,ZNF420,AHCTF1,TBC1D22A,TBC1D14,GMEB1,NSFL1C,SEPT11,ZNF226,GPD1L,ZC3H3,ARL5A,PDCL3,SNX8,ERMP1,EID1,IDH3A,POLR2D,HTATIP2,MEF2D,TMEM147,GSTCD,TANC1,MAT2A,VPS26B,CORO1C,NSMCE2,CAMKMT,PPP5C,PITRM1,TUBB,COMMD10,ZNF445,SRSF6,HABP4,CCM2,FLOT1,BTN3A1,ATG2B,ABHD14B,PPP1R3B,GOLM1,ZBTB45,HUWE1,ZNF260,NAA50,ANXA5,LTN1,KANSL2,UBE3B,NAP1L4,ZNF710,ST8SIA2,RPL22L1,MED22,SPTAN1,STAU1,DDX24,TCTEX1D2,TACC1,MRS2,LDHA,HEBP2,LLPH,RAB3IP,TTC33,PICALM,SH3BP5,SLC19A1,ACOX1,FAM3C,AEN,PARP10,YWHAH,THAP5,GPATCH4,FAM129A,TRIM11,YTHDC2,SNX15,RBM8A,ENSA,NENF,SND1,RUFY1,TRIM65,ZER1,PRNP,KRR1,RAB8A,NUP210,NT5DC1,NOC2L,EIF5,TACC3,RYBP,VPS13B,PTPN18,MIOS,SNRPB,MBLAC2,CDC6,UTP3,PBRM1,ODC1,USP21,TRAM2,FBXO28,BCL7C,ARRDC1,ADAM9,DVL1,NUMB,ZNF564,FUBP1,C1orf74,CTU2,PARP12,ZCCHC9,CENPF,LAMTOR3,CHCHD2,NCKAP1,RSAD1,TNS3,SUB1,RINL,SSBP3,KIF13B,MBD2,XPA,AHCY,RBM3,GLE1,MRPL48,LRSAM1,HDHD2,NTPCR,NSDHL,AMD1,CAMSAP1,ZNF761,METTL22,ICAM2,STYXL1,APPL1,BBS12,ANKRD46,RXRB,SDHB,PCM1,GALNT2,TMEM168,NLRC5,RUVBL2,MYO9A,BTBD10,CCNB2,USP7,GLT8D1,RPLP2,SUCLG1,ARID2,TMX4,SLC2A1,ATP6V1B2,PCBP1,LYN,BCAP31,VAV1,TMEM69,MRPL50,PSMA6,ZNF473,ZNF302,BRPF3,TARDBP,BCAP29,CTDSP2,PRPF19,PPIF,KDM3B,MND1,CLCN3,BIRC3,RAB7A,ANKRD33B,PPIE,CHMP2B,VDAC1,EIF3H,TMEM201,GLOD4,IDE,DHX16,UHRF2,XRCC3,CHMP4B,PARD3,BCL2L12,MCM10,C19orf53,KLHL21,PDAP1,CDCA8,TMX3,GTF3A,ARF1,SLC12A9,TUBGCP2,DNAJB9,HOMER1,WBP1L,POLR1B,RNF5,RBM15B,PPAN,RHOA,RPRD1A,BTAF1,TOP3A,ARHGEF12,PCGF1,DDX23,RAB18,CACNB1,TRIM26,PDCD6,ATP6V1D,L3MBTL3,FAM110A,NEIL3,CTBS,BBX,IMPDH1,TAF12,NR2F2,PGAM1,HIPK3,IFI16,TXN,NUP188,H2AFZ,PNISR,TMEM203,PRKCSH,USP39,UBE2I,PARK7,SLC25A37,ASPHD2,ZNF428,RAB4A,TRA2B,SUCLG2,CISD2,TAF5L,SMARCE1,ZNF800,CDC5L,ZNF524,SGCE,OSBP2,NSUN2,USP22,CLNS1A,EIF3A,ZMYM3,DOT1L,IWS1,ANKRD10,WAS,KIF18B,TPP2,C1orf109,ZMAT3,B4GALT2,PRPF38B,RECQL,C9orf78,EWSR1,GADD45G,RRM1,ACAP1,B4GALT1,CYCS,FAM136A,SUPT7L,TMEM165,CNOT3,NPLOC4,SPAG5,WDR48,RTKN,CEP104,EXOSC7,KLHL5,LRRC8D,PPP4R1,MSH2,PIGG,OSTF1,FBXL7,MRPL40,TNRC18,SYTL3,FAM171A1,APOL1,EIF5A,GCC2,PRIM2,ELL2,RDH10,MFNG,RPS24,GORASP2,CAPZA2,ADRB2,CCT8,MTR,PHF6,PFDN5,SLCO4A1,TTC13,GOLGA2,RBMX,MED15,PIAS2,APPL2,SAMD8,CDKN2A,NUDT3,ZNF511,ATXN3,RAF1,KIAA0232,C2orf49,CD320,EPM2A,CCNA2,MTMR4,BRI3,TP53BP2,AQR,RBM12B,ILKAP,CDK12,SAP30,BRD4,DRAP1,NARF,LRRC8A,ELP4,ABHD11,PKMYT1,ASB13,TRIM28,SUPT16H,EIF3K,CHMP4A,CBWD1,ATF6,XRCC4,ADAM23,PRPF4B,NDUFS1,DEPDC1,MECP2,SECISBP2,HMG20A,WWP2,JAKMIP1,SLC25A36,CCNK,DNAJC8,ELP5,AXIN2,CITED2,JMJD4,KAT2A,RABIF,ADSL,PACS1,BMS1,KCNQ1,OTUD3,ARSK,MACF1,KIF11,COMMD4,KLF6,SMAP2,FADD,SH3GLB1,MYO1F,CBX3,TMEM127,INF2,PPP1R11,DUSP11,DDX5,WDR62,TAF6,ESPL1,PURA,DDB1,DEF6,IPO4,FAM83G,UBL3,PIGM,NAT9,LYRM4,GPR132,UBE2Q1,PTP4A3,BRIX1,MRPL19,ZNF696,SF3B2,PCYOX1L,CDC42,SYNM,GOT2,JAZF1,HADHB,RPF2,SLC35C2,CNNM3,CARM1,SRPK2,WDR41,LARS,ZCCHC10,CCDC138,LRBA,TMEM216,SUMF2,KMT2C,OGFR,PRPSAP1,ASF1B,RPL37,MAN2A2,EIF4ENIF1,U2SURP,MIA2,ZNF268,VPS4A,ATP6V0E1,PPP1R2,PM20D2,XPNPEP3,RGS2,LYAR,FAM89B,POLR2I,TRAFD1,SUGP2,GBA,EIF2A,SYVN1,DAPK3,ARHGAP15,MASTL,UAP1,NFIL3,FN3KRP,YWHAZ,CTSA,TMEM14A,TOB1,TSEN15,ADNP2,TCF12,PRKAB1,MDH2,SMARCA4,ORC1,RRN3,UBXN2A,IARS,CD3EAP,KIF14,EXOSC1,CS,CLTB,DNAL4,CSTF1,POU2AF1,UBQLN4,NXT1,HPDL,PGGT1B,SELPLG,SMU1,ATXN1,GLO1,OGDH,BICD2,CADM1,EDEM2,HERPUD2,TOLLIP,FANCE,MBD3,PDHX,RPS9,ALKBH6,DUS3L,ARNTL,ANP32E,FKBP5,TMEM101,CCDC125,ABCA1,PDCD2L,GCLM,RAE1,DCTN2,NUP54,CHIC2,PAWR,MXD4,DCUN1D4,PIP4K2A,XPR1,FERMT3,KIF5B,KLHL20,SEC24C,RRBP1,ARHGEF2,ANP32A,LDLRAD3,STAT3,MYO5A,NIPAL3,AMPD2,TXNL1,PHF20L1,DCAF6,FAM49B,TMEM39A,ATP2C1,RFFL,COG1,RCOR1,PRMT2,TFEB,LEMD2,UPF1,ELMO1,ZC3H7B,DTX4,ZMIZ1,TERF1,HRAS,CCDC93,FGFR1OP,TMED7,PIGQ,AGPAT1,CNTROB,PPP1R16B,MIS12,GSDMB,TTC9C,PDS5B,NUP153,SENP1,PGAP2,TMEM115,PLEKHM3,DCUN1D5,PLEKHF2,BRMS1,PWWP2B,TRIM47,WDR11,AXIN1,SMG9,TRIM52,LONP2,NDUFV2,PHF23,CERK,SLC4A2,EZH1,ITGB5,LMNA,MCTS1,DDX56,SLC38A5,FOXN2,CARS2,PRRC2A,C16orf72,RB1CC1,ZMYND11,PGS1,MYBL2,UHRF1BP1,SRSF5,MPG,MATR3,CYB5A,NCDN,POLR2J,SETD3,TEX30,PTAR1,CNOT6,NDE1,EGLN1,ZNF207,ANKRD27,ABCA3,SARNP,IVNS1ABP,RMI2,MON1B,TMEM97,NIT2,NUF2,ZNF267,TCF19,TMEM161B,KTN1,APP,PRKD3,CLUAP1,ATP2A2,UTP18,GRSF1,DUT,ZCCHC2,ANAPC7,RNF19A,FAM76B,CLN6,TMEM9,GCC1,RNF169,ADCY7,ATP6V1G1,ENPP4,RNPS1,CDCA2,FKBP3,GPR137,DDX17,CHCHD3,PEX5,CDC16,HIPK2,MBOAT1,TICAM1,PDXK,ZBTB11,ANXA6,TMBIM4,GMCL1,UBE4A,IL21R,ETS1,WRB,ZNF92,PNO1,CAPN2,ADD3,SUV39H2,TTLL12,TPCN1,TMX1,HNRNPM,LYPLA2,MFSD12,LDHB,PPP3CA,NUDT8,POLK,JTB,EMP3,MTMR12,ZP3,PDE3B,KIF18A,CCDC6,WNT5B,MAPK6,C4orf46,LY75,SLC25A19,RGL1,PSAP,WDR76,IGBP1,FAF1,SNAPIN,COX15,AGRN,THOC1,GNPDA1,GPBP1L1,PPP1R15B,CSNK2A1,EBNA1BP2,GIT2,BIRC2,ATPAF1,DLG5,ABL2,XRCC2,ZFYVE27,MCMBP,PTPRK,CDC37,SP3,METTL1,EXOSC6,HARS,GMFB,ESYT1,ANLN,RAB5B,RHEB,DPYSL3,TBC1D17,TIMM13,CDCA4,TONSL,NRM,NAGLU,ACTB,ZNF45,TMUB1,CTCF,ASAH1,DOCK11,CRLF3,ASXL2,LRRC14,NUS1,SLC27A4,AFF1,MDFIC,MAML1,CYTH1,NQO2,UTP15,EIF2AK1,EIF4G2,ZDHHC3,MOSPD3,ITPRIPL1,CDC27,TBPL1,PRMT7,KCTD7,NDUFA5,CYLD,UGP2,COPE,ZADH2,GGPS1,RAD23A,ABRACL,PDK2,ATP6V0B,STRBP,DUS4L,MRPL34,PDCD2,SAP30L,CLPTM1,SLC39A9,RPL29,RPL35,BTG2,DNAJC9,MTMR6,NFATC2,KDM1B,ARL5B,USP36,CCDC127,MRPL2,ATP1A1,CLK3,MAFK,PSMD3,NDUFA11,CEP55,ZNF436,DNAJC17,NCOA1,SLC25A39,ZC3HC1,ZNF146,ATXN7L2,CDC40,SMAP1,GOLIM4,RRP15,GNE,SMC6,ARFIP2,NKRF,CHAC2,BZW2,WRNIP1,SS18L1,CENPM,PTGES3,CAMK2G,MLEC,ZNF202,PPWD1,FAM50B,RHOT2,NEU1,TPD52L2,GOLGA7,TWSG1,PGRMC1,GLG1,FAM126A,RPS6KC1,UBE2C,PPCS,NDUFB6,TMEM41B,ZDHHC8,PLXNA1,CCNB1,SLC20A1,COMMD6,POLR3K,C14orf119,ASAP2,SNUPN,CNPY4,PLCL2,TFG,SEH1L,ATG9A,PBK,MKI67,DDX20,AMDHD2,SLC17A5,GALNT7,CCNF,FOXRED1,RBM47,PTER,WDR4,DHTKD1,TRAF5,HDAC2,PWWP2A,HSPH1,LIME1,MAPRE1,CHTF18,ADO,KIF23,SLC35B1,NOTCH2,PMF1,JMY,FKBP1A,SLC31A1,SNX18,ATIC,CTPS1,ATP6V0A2,PIKFYVE,RNF135,LPCAT1,EEF1D,TMED2,FTL,PHF10,DDX28,SIGMAR1,PIP4K2C,FAM133B,RIT1,PLEC,KDM3A,SF3A2,FAS,EPRS,ZNF777,TMEM54,QARS,PPP3R1,TCOF1,NRBP1,CABLES1,DNMT3A,RWDD1,CKLF,TRIP10,SF3B1,RPS6KA1,CAST,SUZ12,RAC1,GPR89A,OLA1,GNB2,FLAD1,APLP2,KDM2A,TNPO2,CDKN1B,TALDO1,GPX4,ATP13A1,MAPRE2,RFC3,ERF,CUL3,SLBP,KIAA1586,H2AFV,POLG2,GAR1,PSMB9,DHX57,NSA2,HSPA4,MRPL55,JAK1,TBL3,GOLGA8A,SEL1L,H2AFX,KLHDC4,B4GALT3,PDCD11,ATMIN,POLQ,POU3F2,OTUD5,NCOR2,ANKRD13D,PKP4,SCAMP3,BABAM1,CDCA3,SLC25A12,BLM,TMCC3,GTF2F1,RPL17,CRAT,AHSA1,PRC1,UPF2,COPS7B,SLC38A10,CNOT6L,CNPY3,UBE2M,IFT46,TMEM160,TSHZ1,ZFP64,STRIP1,DENND4C,DENND1B,WDR18,RPL8,ILF3,LRRC1,RHOT1,MARK2,TSR2,ECH1,PRDX1,PLD3,NUCB1,FBXO21,GNA12,C1orf131,PRDX3,PFDN4,HNRNPH3,STX18,TFDP1,KHSRP,ASNA1,CPEB2,SSSCA1,VPS29,BYSL,S100PBP,MIB2,IER2,NOP2,UBN1,DCAF15,NF1,FLYWCH2,ALKBH5,MOGS,UBE2Z,TAF6L,BECN1,MAPK14,SNAPC4,RNF103,BCAT2,MBD4,C18orf32,METTL14,ZNHIT6,IMPAD1,RCSD1,PHTF1,SRI,KIF22,ZBTB22,NFU1,OGG1,TRIM14,ELOF1,COPS8,FYTTD1,TRIM8,RRM2,SOX4,ABHD5,CXXC4,UBTF,PAF1,UEVLD,SPATA2,PQBP1,IARS2,ATXN2L,GALNT10,STARD3NL,RPS15,PIGN,AGTRAP,CIB1,XPO7,SRRT,ZNF449,CAPZA1,KIFAP3,BCL2,N4BP2,HP1BP3,VOPP1,THNSL1,ISG15,CAND1,C22orf46,GNAS,TSC1,RBM25,CDCA5,ZFP90,NANP,RBBP4,ZBTB24,SMARCD1,MBD1,WASF2,MMACHC,TOMM20,IFI27L1,GNPNAT1,MPHOSPH8,HNRNPUL2,CHD1,MEAF6,CCDC50,AKAP8,PARL,RPN2,CHTOP,FAM3A,F2R,TMEM14C,SCYL3,ABI1,HTRA2,MOSPD1,RLIM,FAM172A,ZNF500,PSMB7,NLN,WIPF1,BOLA1,BUD13,NDUFB1,PEF1,EIF3G,BTBD1,TAB2,CHCHD1,TULP3,WDR59,CANT1,SCARB1,GAS2,USP11,SMURF1,PPP2R2D,TSPAN5,CDS2,MAGEH1,MRPL42,EYA1,CDK2AP2,MRPS26,LETMD1,KLF13,HDDC2,RGS1,MAN1A1,FBXO5,GART,PELO,TANK,BRD7,MRPL11,SAMD4B,ZDHHC18,GTF3C6,POLR3GL,WDR81,MEN1,ZNF407,MFN2,COX8A,ZRANB2,MBD6,SRSF3,ATP6V1C1,IDH3B,TATDN1,TSC2,LACTB2,CMTM6,RBM4,ZNF275,ANKRD39,RPL23A,CDKN2C,USF1,DNAAF2,MECR,AP1M1,UPRT,CRY2,ECD,RNF26,TIPARP,LRRC59,ANKRD9,RHBDD2,MGAT5,BAK1,ZNF559,RHOBTB3,GABPA,WBP1,NUTF2,ARF4,GINS4,KRIT1,AHNAK,RAD18,PDRG1,RNASEL,CHPF2,SMNDC1,PDCD4,NXT2,HIVEP3,KIAA0100,CLSPN,RHOC,DHX9,PDCD7,PSMD9,HAUS2,COPB2,TFAP4,CD59,RNFT1,MEGF8,RIMS3,FBXO7,EFTUD2,CPSF4,MRPL21,PHKG2,LUC7L2,SRSF11,EIF3L,MTA2,TYW1,USP10,ITM2A,SSR2,BCLAF1,MTX1,SFXN5,FNTA,PDLIM1,TXNDC16,ZNF830,TMEM159,MRPL3,ALS2,FAM72A,TRIM41,KARS,NQO1,POC1A,ANK3,PTTG1,TPX2,TBC1D13,DAZAP2,GLRX3,STMN1,C19orf48,REPS1,ABHD16A,FBXL6,SH3BP1,MTA1,UBA5,CLCN6,INTS12,RPRD1B,SZRD1,CGGBP1,CPNE1,FAM118B,GOPC,E2F3,CIRBP,RPL38,CRNKL1,PFKFB3,GORAB,RAB1A,GIGYF1,TMEM184C,PPP2CA,KIF2A,CCDC14,LSM6,RNF38,SNRPG,CENPBD1,DMWD,USP13,MZT1,ZFP91,TRMT6,IP6K2,WDR5,SLC25A43,IFT27,PMVK,NEIL2,RRP36,SRXN1,RPA2,PSMD2,CLIC4,PDCD10,COQ4,ITGB8,ARF5,ARHGEF1,GTF2H2,FBXL19,TTPAL,UTP20,MAGT1,GPS2,DBI,SSNA1,MRFAP1L1,CD81,TMEM131,WDR13,FANCI,PAPOLA,CREM,TET3,FANCL,GLIS2,IL6ST,INTS1,POP7,SLC44A1,MTPN,ASB6,PLK1,RPP25,CELSR2,SEPT9,RBX1,APH1A,RAD51AP1,ZBED5,CKAP2L,PSMG1,UBE2V1,EAF2,IL12RB1,KRTCAP2,LUC7L,LSG1,NECAP2,ALG3,TRIM4,AGPAT2,CHD3,ZNF367,E2F4,PRPF4,KPNA2,BEND6,CLN3,DNAJC30,FAM208A,NGLY1,POT1,MYL12B,CCDC137,RMND5A,HJURP,PHB2,FAM53C,DNAJB2,NKD2,SDC2,KLC1,CDK13,ADCK5,COX4I1,RAB6A,DNAJB1,ARID1B,C1GALT1,MLX,UBE2Q2,CCP110,ZNF746,ARL6IP1,CTR9,NIPSNAP1,ABHD2,DCAF8,ACSL3,LDB1,MAP4K3,ARMC8,RBM38,IRF5,NMT2,HAUS8,MBIP,ORMDL2,COX7A2L,ZDHHC7,FAM122A,SIL1,DTD1,UNC13C,BCCIP,SART1,TRAF7,NDUFAF2,TOR1AIP1,ZNF416,LAGE3,ZFYVE21,TM9SF3,RRAGC,ZNF121,OIP5,NRF1,WDR44,PIN1,PPME1,EFCAB11,RPAP1,CABLES2,TOP1MT,LMAN1,AHCYL1,STRAP,SPSB3,ZNF583,SNX25,ARHGAP17,POLR2G,ZNF780B,PPT1,NUP155,DCLRE1C,MRPS14,RHBDF2,SUGP1,RBL1,FASTK,UBXN2B,STK38,AP1S1,SPRYD4,SLC22A23,H3F3A,CHID1,SMAD4,RAD51D,SLC30A9,NADSYN1,CMAS,UNK,HMGN3,NCAPG,SCYL2,FZD6,HERC3,GTPBP3,CTSS,ORC3,RNLS,YTHDC1,ACP2,CSRP1,HMGN5,METTL5,ABCF2,TUFM,RANGAP1,PNPLA8,HAGH,API5,ZFR,SEC23IP,E2F1,USP20,TMEM219,RBPJ,MAX,PDCD6IP,LUZP1,GXYLT1,ADAM10,CXXC1,TSC22D3,AP3M2,CUL1,GYG1,NANS,OAT,MYEF2,ANKRD26,PA2G4,NOL11,FIZ1,ZNF200,MARCH2,SLC26A2,SRP72,KLF10,LACTB,CBFB,RFC2,RAB2B,PRIM1,MAP3K4,HHEX,RPS14,LUC7L3,MAP4,MRPL27,BTF3,PTPDC1,CCDC59,NMD3,PTOV1,COX5B,DNAJC5,SCOC,DHPS,ANKH,PRKAA1,VAV2,C16orf87,GSPT2,DLGAP4,TATDN3,PXMP2,PRPF39,PSEN1,ZNF79,PDXDC1,VPS25,NDUFS7,YY1AP1,C12orf10,FAM192A,RPN1,LHX8,ARPC5,ZNRF2,DAPK1,TPST1,PIK3IP1,CYC1,SOCS5,FDFT1,PIGT,WDR1,EMB,ZNF574,C1orf35,EXOSC9,ARID1A,PTTG1IP,C9orf40,FXR1,GOSR1,MAP2K2,TWISTNB,AKAP1,XRCC5,HMGN2,PI4K2A,CAT,SEC31A,DERL1,HSPBP1,MTHFD2,CEBPG,ARAP1,FAM83D,USP32,CABIN1,SMPD4,GPI,CYTIP,TP53RK,REPS2,RAB11B,UROD,SLC39A13,POMP,BCL2L1,NUDT19,DECR1,RALB,SIAH1,LPIN2,ADCY9,SOCS6,MRPS27,TTC3,RNASEH2A,CFL1,ANKLE2,CDC123,OAF,VDAC2,EDF1,ERC1,EML4,AMZ2,ANKZF1,ZNF282,RAD51C,DSN1,DDOST,HINT1,DGCR8,SAFB,HAGHL,LMBR1,FTSJ1,RWDD4,NCLN,BEND3,EYA2,DYNC1LI2,B4GALT5,SLC41A1,MANBA,TKT,FAM76A,CBLL1,ARGLU1,LANCL1,POFUT1,FAM8A1,HEATR5B,HLA-A,EBP,RFWD3,NDUFA2,FUT8,FJX1,BTF3L4,PTPN11,MRPL54,FEM1B,RPL19,CNN2,MTX2,MSH6,PDLIM2,LONRF3,RFXANK,FBXO9,GUF1,RPL32,ZHX1,OAZ2,NDUFS5,WDR91,GPR89B,RORB,POLA2,ZNF76,MTX3,COPA,UQCR10,HMGXB3,PHRF1,ABCB10,COMMD5,MAP1LC3B,DST,SIVA1,RAB35,GPATCH1,TCEA1,DRAM2,DEAF1,TRAPPC13,SNRNP200,NCK1,LAP3,VHL,SREK1,ARHGDIB,PITPNB,BRWD1,PPM1G,SH3GLB2,BAZ1B,CAB39,ACBD4,STK11,CLU,CHEK2,ZSWIM3,TSTD2,MRPL13,CHPT1,DCAF5,CAPN1,UBE2D3,NSMCE4A,PPP1R12A,ZCCHC8,GORASP1,NACA,UBXN1,PCSK7,EPN1,RPL15,THRAP3,TTF1,QSOX2,NUP205,PRPF18,CHKA,DTL,ZRANB1,MCPH1,SLC12A2,ATP6V0D1,CSNK1G3,CREG1,NUDT4,RPL6,VKORC1,SLTM,EVC2,KLHL15,SIAH2,SLC16A1,EHD4,SNRNP70,C11orf1,APOL2,N4BP2L2,SNX27,CHMP2A,CORO7,FEZ2,PMS2,UCK2,UCK1,CLCC1,EXT2,MXD1,USP5,HNRNPA2B1,SAP130,NVL,PPP6C,CYB5R1,ZNF770,EBAG9,RNF25,PCGF6,METTL2A,PON2,HNRNPR,STAT6,HPS5,MAPK1,BRD9,TMEM33,NAT14,DNAJC2,TRIP12,SHPRH,SCYL1,VPS45,MYO9B,GFM2,SPPL2A,FASTKD3,FGFR3,MZT2A,PPIG,ZDHHC13,TMEM99,H2AFY,ATG13,NDUFS8,ERI3,FBL,FRMD8,SLC35A1,MICAL3,TGFB1,B3GALT6,ELOVL5,HEMK1,TIMMDC1,HELB,PSPC1,MIER1,SCFD2,NDRG3,CDK11A,MTMR3,MEGF9,ACAT1,CENPT,PLOD3,RAB3IL1,ZSWIM6,RAB14,ADD1,MRPS15,KDM4A,XIAP,DHX8,GLUD1,ANKRD23,PABPC4,CALM2,CDK5,PSMD1,NEK6,NSRP1,RABGAP1L,SRSF4,FNIP2,KCNAB2,PCBP2,MLST8,PLK3,ZNF672,HSDL1,MRPL43,TOPORS,MCL1,SMC2,PPFIA3,ICMT,SLC50A1,STOML2,LIMK1,ZNF689,PRDX5,ATE1,MLYCD,ATP6V0C,ST3GAL2,FBXL3,TFDP2,E2F2,PFKP,AAAS,DDX42,SSRP1,MRPL9,MRPS2,STRN4,TOP2B,ZNRF3,TMED3,DDRGK1,RAVER2,GNS,INTS7,INPP5A,MCM5,PHF14,ZNF326,UBE2QL1,NAGPA,ETV3,TSPYL4,TSPAN31,DHX29,TEX10,MAN1B1,CBFA2T2,ABCF1,RHOB,LRRC14B,DTWD1,PTPRF,SCARB2,OSBPL11,CCDC86,DUSP3,SLAIN1,MDH1,HEXA,RNF139,SNX14,ZNF296,TRERF1,UBR2,CHD1L,ACTR3,WDTC1,MYH9,CREBL2,NIPA2,PRKACA,SAFB2,ANKIB1,STAM,ARL6IP6,RAB21,SP100,ZKSCAN1,DDA1,NUP107,ANKRD13C,MAVS,CEP63,RBM15,ATF2,DCTN1,SHOC2,PSRC1,MAP4K4,WBP2,ATP6V0A1,NUSAP1,DNAJA1,TAZ,C19orf54,TAF2,SEC61A1,WDR7,CBLN2,FUS,GEN1,LRP8,COIL,LRCH1,GALK1,ZNF786,RPS2,SESTD1,TRAK1,JMJD6,SIKE1,AKT1S1,KRI1,FBXO3,ERH,GATC,NDUFB4,PPP1R8,PRDM4,GTSE1,GEMIN6,DCP1A,SGCB,S100A6,IMPA2,NUDC,PDPK1,TK1,GUK1,TNFAIP3,GALC,ZNF512,KIAA0930,MRPS10,DDX39A,RPA1,ZNF180,ZNF862,KEAP1,POLE,TATDN2,PITX1,CAPN7,LRPPRC,PML,HMGB2,USF2,ANAPC4,SRM,DDX47,MCCC1,CDC42SE2,S1PR2,CDIPT,SEC16A,SSR1,LIN9,PCNA,ZNF639,TRMU,PIK3R2,ETV6,TXLNA,PPCDC,FAM86C1,MYBL1,MRPL32,CCAR1,ABCC5,PBXIP1,BAZ2A,TLK1,MRPL12,EZR,LNX2,LRP5,BRCA1,PRKRA,STX16,EPB41,OPTN,SEPT1,SOCS4,QRSL1,PIEZO1,OSGEPL1,GLCCI1,NUDT11,NAA60,GEMIN7,SEPHS2,LZTR1,RACGAP1,PPP3CB,B4GALT4,RLF,RAPGEF6,SNRNP25,RB1,VASP,MED8,VMP1,PPIL2,MEA1,TIMELESS,AHDC1,ALDH18A1,TMEM8A,ABCC1,PREB,TRAPPC9,AACS,MEMO1,KRAS,RTF1,UBE4B,NFATC2IP,LY6E,ARPC1A,ZNF174,PSMC4,GOLGA4,PALB2,SYNCRIP,PRPS2,NIPA1,TIGD2,RNF114,FOXM1,MRPL39,XAB2,SUMO2,DUSP22,COMMD8,RPL11,CSDE1,MDM2,CORO1A,MINPP1,METTL9,POC5,DVL2,GM2A,PSMA8,COQ10B,CPOX,TIGD5,SLC26A6,CYP20A1,PRPF3,TXNL4A,RPSA,SRSF1,DNAJC10,ZNF700,SCAP,PLEKHG4B,TIMM17A,FAU,LTA4H,AP2S1,USP53,INTS2,CTDP1,MIF4GD,CDT1,ARID5A,SUMF1,GGA2,AP3S1,CSNK1A1,RMI1,TFRC,PTPN2,IRF4,GSTK1,NDUFV1,SLC1A4,CWC27,SLC35B4,DDX31,ABCD1,RPAP3,CNTN5,SNX2,ZMYM5,CHCHD6,BSDC1,KPNA4,CDKN2AIPNL,FBXO41,BIRC5,TFE3,SNAP29,CDCA7L,PKD2,ACADM,CHMP7,SAT2,GCSH,ZNF496,TMEM109,TAP1,YTHDF3,NHLRC3,IKBIP,EIF1B,ELMOD2,KIFC1,DBNDD1,CYB5RL,PARPBP,CDC25B,PRADC1,DNMT1,NOL12,ORAI2,USO1,AKT2,NOL8,GNG7,AURKB,MCFD2,SLC25A5,ZFAND5,MAK16,STT3A,TMED10,PSMD8,EIF2D,ITGB1,PTPN7,UQCRH,RRS1,ARRB2,RTN3,ZNF598,SVIP,DDX58,WSB2,PPIB,MUT,GMFG,HLA-E,NDUFA4,MAN2B1,METTL3,CFLAR,NDUFS4,RNF121,MEX3C,KLF16,HDAC7,DAD1,BDH1,PCYT2,GNAI2,ANKHD1,TERF2,MORC3,KCTD20,SEPT8,DCTD,PKM,TOMM40,PATL1,ADSS,SERTAD2,ZFP92,DCK,ERGIC3,ACLY,LPCAT4,VCPIP1,YY1,PPP6R3,PPP6R2,MAP3K5,RNF14,CDK2,ZC3HAV1,SYS1,ZBTB37,URB2,EIF3D,MAGED1,KLHL18,ADPGK,SLC25A44,AP1B1,SDHA,PAIP2,PHC2,CRKL,TERF2IP,MOAP1,CYHR1,ZNF75D,SHC1,UCHL5,NAA35,CCT2,CDKN2AIP,MKLN1,HMGN4,LYRM1,GALK2,CDC23,SHCBP1,AP4E1,PRDM11,VEZF1,PPP2R5A,ACYP1,STAT1,PPA2,TRIM32,RHEBL1,R3HCC1L,C1orf112,TCF3,MRI1,BRAP,AGPAT3,MYNN,SDF2L1,SPR,RAB11A,REEP5,FOXO3,MAD2L2,CCDC28A,PIP5K1C,RBM17,MAT2B,PTEN,CENPJ,TAGLN2,OSTC,PACS2,NCOA2,SMC4,RNASEH2C,NEK7,NET1,PARP4,TBRG4,ANAPC2,RPL27A,YIF1A,SGSH,HGS,TTLL4,SLC38A7,MFAP1,CCDC69,BRWD3,ESYT2,SKA3,NPHP4,UBE2E2,HNRNPAB,PLXNC1,TMEM184B,ST13,DNAJC24,ZNF107,SLC29A1,KIF2C,AGFG1,SIRT2,FKBP2,USP48,UBQLN2,SNRPD3,CUTC,EDC3,UBLCP1,ZNF804A,RAP1A,THADA,EIF4A3,AP3S2,ATG3,DPYSL2,PPP1R12C,AKR1B1,NDUFB9,JOSD1,RP2,TTC4,TECR,ARID4A,FGFR1OP2,TIMM50,TDP1,DPM1,FOPNL,SLC16A7,WDR82,SLC25A22,STK17B,DHX15,CHAF1A,GEMIN5,COPS6,SASS6,RPS26,PSMC1,SLC12A7,TBC1D12,TM9SF4,ZNF768,UFC1,MED13L,TIA1,MEF2A,EPHX2,PITHD1,RHBDD1,NFATC3,BANF1,ZNF335,BUD31,YBX1,KNTC1,ACAD8,UBE3C,ZNF189,ALDH9A1,KDELR1,TSTA3,CIC,OXR1,PSMA1,SEPT7,NAP1L1,NSMF,ODF2,EXOC4,KIAA1328,NUP62,PITPNA,NAA20,PTDSS1,PDSS2,C7orf26,TMEM106C,IMMT,ASH1L,CHERP,WDYHV1,PLAGL2,CHKB,IRF3,TWF2,PAIP1,ANKRD28,ANKLE1,FARSA,SAR1A,SCAMP4,APOOL,PDIA6,ACSL5,TOR1AIP2,AZI2,GFER,RAD54B,DAP3,TMEM41A,ZNF317,GADD45B,AKNA,REEP4,CBX4,MIF,KIF3B,GOLPH3L,SH2D3A,CASP6,TOR3A,SRGN,DBF4,MFSD10,SAC3D1,CTNNBL1,YIF1B,CLDND1,TTC17,SLC25A1,GINS1,PAQR6,CSNK1G2,TELO2,ADAM17,HMGN1,NASP,ASPM,PPP1R21,PRKAR1B,SYMPK,TARS,SNRPA,MAPK3,HLA-B,ATAD2,PLAA,ZNF330,OSBPL8,KBTBD7,PREPL |
| 1.966e-02 | -3.93 | GO_MEMBRANE_LIPID_METABOLIC_PROCESS | MSigDB lists | GO_MEMBRANE_LIPID_METABOLIC_PROCESS | 175 | 37 | 17377 | 2626 |
PIGM,PIGN,PIGQ,HEXB,CERK,ASAH1,SUMF1,B4GALT4,CREM,ITGB8,PIGG,GLTP,SPTSSA,ST8SIA2,CLN6,HTRA2,GM2A,PGAP2,CSNK1G2,PIGT,DPM1,PPT1,GALC,GBA,ARSK,NEU1,PPP2CA,ALDH3B1,ORMDL2,CERS6,SAMD8,CTSA,ST3GAL2,SMPD4,PSAP,CLN3,HEXA |
| 1.966e-02 | -3.93 | GSE3982_DC_VS_MAC_UP | MSigDB lists | GSE3982_DC_VS_MAC_UP | 175 | 37 | 17377 | 2626 |
GLT8D1,NSMCE4A,UGP2,ZNF768,DAP,CBLL1,MEF2A,FAM136A,DUSP22,PPP1R16B,SYNRG,PARN,RUFY1,SLC25A36,CRKL,RIMS3,SRI,SPSB3,SRPK2,PGS1,CIRBP,ANAPC2,DCLRE1C,TFEB,TRAM2,FBXO21,SETD3,NFIL3,PRMT7,VCPIP1,PRPF4,VPS4A,RBPJ,RRS1,ANXA11,PFKP,CWC25 |
| 1.968e-02 | -3.93 | REACTOME_TRANS_GOLGI_NETWORK_VESICLE_BUDDING | MSigDB lists | REACTOME_TRANS_GOLGI_NETWORK_VESICLE_BUDDING | 57 | 15 | 17377 | 2626 |
GNS,FTL,SNX2,SNAP23,DNM2,AP1M1,AP1S1,TGOLN2,ARF1,AP1B1,AP4E1,AP3S1,PICALM,TFRC,SNAPIN |
| 1.968e-02 | -3.93 | GTGTCAA,MIR-514 | MSigDB lists | GTGTCAA,MIR-514 | 57 | 15 | 17377 | 2626 |
TCF12,ZNF282,USO1,EIF4ENIF1,BRWD1,PTEN,RBX1,OAZ2,PPP3R1,KLF13,UBQLN2,ST8SIA2,IGBP1,DHX57,CARM1 |
| 1.971e-02 | -3.93 | CBX4 (chromobox 4) | protein interactions | 8535 | 92 | 23 | 17029 | 2761 |
MBD1,DNMT3A,DCAF6,PARP12,MAPKAPK3,PCGF6,SDC2,KCTD17,LNX2,CSNK2A1,UBE2I,KDM3A,ISG15,PHC2,ANKRD26,RB1,KDM2A,MRPL55,HIPK2,YWHAZ,H3F3A,CBX4,SLC25A1 |
| 1.971e-02 | -3.93 | SPP1 (secreted phosphoprotein 1) | protein interactions | 6696 | 92 | 23 | 17029 | 2761 |
UBQLN4,STAU1,HMGN1,NACA,USP42,RPL15,CSNK2A1,DNAJB1,NCKAP1,ITGB5,CHD1,ZNF804A,EIF3K,PLD3,CTNNBL1,TMEM168,ATP2A2,GRIPAP1,SEC24C,ITGB1,CISD2,TUBB,SNAPIN |
| 1.971e-02 | -3.93 | negative regulation of binding | biological process | GO:0051100 | 163 | 35 | 17256 | 2622 |
MAPRE1,DNAJB2,HABP4,STMN1,PSEN1,PARK7,MAD2L2,GTF2F1,TFAP4,SP100,EIF4A3,RALB,PIN1,SRI,GTSE1,CARM1,CPNE1,PPP3CA,BTAF1,GTPBP4,ADRB2,AURKB,SYMPK,MAPK3,PTPRF,GOLGA2,E2F1,ZFP90,ACTB,ROCK1,DVL1,RUVBL2,ARRB2,HDAC2,IFI16 |
| 1.977e-02 | -3.92 | TRIM41 (tripartite motif containing 41) | protein interactions | 90933 | 97 | 24 | 17029 | 2761 |
TRIM41,MAGEH1,ZFP64,KIAA0232,ZNF574,RNPS1,BRAP,ERBIN,UBE2I,GGPS1,GFM2,APP,ANKRD28,PHC2,TRIM4,ZNF473,TRIM26,AEN,TRIM52,GLCCI1,ANKHD1,SRPK2,ZNF564,ZBTB24 |
| 1.982e-02 | -3.92 | GO_SMALL_MOLECULE_METABOLIC_PROCESS | MSigDB lists | GO_SMALL_MOLECULE_METABOLIC_PROCESS | 1665 | 281 | 17377 | 2626 |
PPCS,TXN,NDUFB6,HEXB,GLUD1,OAT,PARK7,CALM2,USF1,MECR,SUCLG2,UPRT,SLC26A2,DNMT1,KCNAB2,AKT2,AMDHD2,ICMT,STOML2,PRDX5,DHTKD1,MLYCD,COX5A,UQCRH,ST3GAL2,CHPF2,PFKP,B4GALT2,NDUFV2,COX5B,MUT,DHPS,ADO,PRKAA1,RRM1,B4GALT1,NDUFA4,CYCS,MAN2B1,PDXDC1,NDUFS7,NDUFS4,GNS,INPP5A,ATIC,BDH1,MSH2,ATP6V0A2,CYC1,LPCAT1,PPA1,CARS2,FDFT1,RDH10,DCTD,MPG,KDM3A,MTR,CYB5A,RDH11,ADSS,CAT,EPRS,MTHFD2,QARS,DCK,ACLY,LPCAT4,MDH1,SAMD8,SMPD4,GPI,HEXA,ACSF2,NUDT3,EGLN1,KARS,DNMT3A,TRERF1,UROD,OLA1,WDTC1,NIT2,ADPGK,SLC35B2,SDHA,APP,CD320,FLAD1,NUDT19,DECR1,DUT,LPIN2,ADCY9,TALDO1,CLN6,GPD1L,PDCL3,GPX4,ADCY7,ENPP4,IDH3A,ATP6V0A1,PFKFB3,GALK2,NDUFA7,POLG2,TAZ,SERP1,MAT2A,ALDH3B1,HINT1,PPA2,MBOAT1,PDXK,B4GALT3,GALK1,NDUFS1,B4GALT5,MECP2,MRI1,TKT,SLC25A12,ABHD14B,IP6K2,PMVK,POFUT1,NEIL2,EBP,MAT2B,ERH,GATC,COQ4,NDUFA2,PTEN,NDUFB4,CRAT,FUT8,NDUFA3,LYPLA2,IMPA2,LDHB,TK1,GUK1,LDHA,ADSL,PDE3B,ECH1,SLC19A1,KEAP1,ACOX1,DBI,NDUFS5,COX15,LYRM4,GNPDA1,UQCR10,MCCC1,MAPK14,CREM,PCYOX1L,MBD4,BCAT2,GOT2,EIF4A3,IMPAD1,SLC44A1,HADHB,PPCDC,AKR1B1,NDUFB9,TECR,OGG1,LARS,DPM1,HARS,RRM2,LRP5,BRCA1,ODC1,PRPSAP1,ABHD5,MAN2A2,UEVLD,IARS2,QRSL1,CLN3,CHPT1,NUDT11,SEPHS2,COX4I1,B4GALT4,EPHX2,CHKA,NUS1,SLC27A4,AHCY,ACAD8,ALDH18A1,ALDH9A1,ABCC1,NSDHL,NUDT4,ERLIN1,AACS,ACSL3,AMD1,GBA,THNSL1,VKORC1,SDHB,COX7A2L,PRPS2,TBPL1,SLC16A1,DTD1,NANP,PDSS2,APOL2,MMACHC,PRKAB1,NDUFA5,SUCLG1,UGP2,MDH2,MRPL39,SLC2A1,UCK2,UCK1,CHKB,ATP6V1B2,GGPS1,EXT2,FARSA,PDK2,IARS,CS,CYB5R1,AHCYL1,MINPP1,ACSL5,HPDL,GLO1,OGDH,NDUFB1,PDHX,SCAP,NDUFA11,SCARB1,MAPK1,LTA4H,ABCA1,MIF,GCLM,NADSYN1,CMAS,GNE,GART,NDUFV1,NDUFS8,ABCD1,PTGES3,MYO5A,SLC25A1,AMPD2,B3GALT6,TGFB1,TXNL1,ELOVL5,PNPLA8,HAGH,TARS,MAPK3,HSPA1B,COX8A,IMPDH1,ACAT1,ACADM,IDH3B,PGAM1,GCSH |
| 1.984e-02 | -3.92 | ACTTTAT,MIR-142-5P | MSigDB lists | ACTTTAT,MIR-142-5P | 272 | 54 | 17377 | 2626 |
TCF12,SCOC,TRIP10,ARID2,RHOC,ZFYVE21,ARGLU1,UBE4A,DCUN1D4,BECN1,PCBP1,PAIP1,MAT2B,CDK5,LHX8,BRPF3,VMP1,GRSF1,MBD2,SRI,MEA1,PDS5B,UBE3C,ST8SIA2,PCBP2,MSH6,CLCN3,RHOA,MKLN1,KLF10,BAZ2A,CIC,GOPC,MCL1,RHOT1,TANC1,BTBD1,CBX3,MASTL,MBIP,TMEM54,HNRNPH3,CAPN7,PPM1G,SLAIN1,FBXL3,SLC22A23,BTBD10,CPEB2,PURA,ABCA1,ALS2,ATXN7L2,PRPF4B |
| 1.984e-02 | -3.92 | Factors involved in megakaryocyte development and platelet production | REACTOME pathways | R-HSA-983231 | 156 | 36 | 10287 | 1696 |
KIF3B,RAC1,VPS45,KLC1,KIF23,RACGAP1,IRF3,KIF2C,DOCK11,PRKACA,KIFC1,CDK5,KIF5B,CDC42,KIF13B,CAPZA1,KIFAP3,KIF22,CABLES2,CARMIL1,PRKAR1B,KIF15,RCOR1,CAPZA2,KIF11,MFN2,AKAP1,KIF2A,RAD51C,KIF18A,KIF18B,MAFK,H3F3A,CDK2,CABLES1,HDAC2 |
| 1.986e-02 | -3.92 | LKB1 signaling events | Pathway Interaction DB | lkb1_pathway | 42 | 14 | 2226 | 426 |
TSC1,TSC2,EZR,CAB39,STK11,YWHAZ,AKT1S1,CREB1,YWHAH,PRKACA,MARK2,SMAD4,MLST8,CDC37 |
| 1.989e-02 | -3.92 | GSE16385_ROSIGLITAZONE_IFNG_TNF_VS_IL4_STIM_MACROPHAGE_DN | MSigDB lists | GSE16385_ROSIGLITAZONE_IFNG_TNF_VS_IL4_STIM_MACROPHAGE_DN | 192 | 40 | 17377 | 2626 |
SEPHS2,LZTR1,GGNBP2,GMFG,SESTD1,LAMTOR3,NKRF,SECISBP2,RCOR3,ZNF518A,CUTC,CCDC28A,UBXN2A,CS,AKR1B1,OSTC,GPD1L,FAM171A1,MORC3,NOL12,SGCE,POLR2G,GALC,MAP4K3,THNSL1,ANKRD10,FNTA,PPP2R5A,ZNF330,ACOX1,CDCA7L,APPL2,WDR7,MEGF9,CLU,RBBP4,MAPK1,RNF14,MZT2B,POT1 |
| 1.989e-02 | -3.92 | GSE15930_STIM_VS_STIM_AND_TRICHOSTATINA_48H_CD8_T_CELL_DN | MSigDB lists | GSE15930_STIM_VS_STIM_AND_TRICHOSTATINA_48H_CD8_T_CELL_DN | 192 | 40 | 17377 | 2626 |
DNAJC2,HLA-E,TAP1,LCLAT1,CMTM6,PHC2,IRF4,CTSS,PELO,TIMELESS,TNPO2,TAP2,ZRANB1,MTX2,PABPC1,PPA1,TRAFD1,ATP13A1,DDX24,HMGN5,CREG1,TOR1AIP2,ICAM2,OGFR,MAT2A,ISG15,NMT2,GEMIN5,HLA-B,HHEX,ATP1A1,PDLIM1,FAM3C,STAT1,PML,TCOF1,CLN3,NRBP1,CBX4,IPO4 |
| 1.989e-02 | -3.92 | chr9q34 | MSigDB lists | chr9q34 | 192 | 40 | 17377 | 2626 |
NUP188,TMEM203,MRPS2,VAV2,UCK1,TBC1D13,WDR5,SEC16A,ZNF79,TTF1,QSOX2,SNAPC4,COQ4,CRAT,PPP6C,DAPK1,FBXW2,SLC27A4,DDX31,GLE1,LRSAM1,ASB6,MED22,SPTAN1,RPL35,MAN1B1,EHMT1,CAMSAP1,PSMB7,LRRC8A,ANAPC2,EDF1,TSC1,GOLGA2,AGPAT2,ODF2,SH3GLB2,ARRDC1,USP20,SSNA1 |
| 1.989e-02 | -3.92 | GSE32034_LY6C_HIGH_VS_LOW_ROSIGLIZATONE_TREATED_MONOCYTE_UP | MSigDB lists | GSE32034_LY6C_HIGH_VS_LOW_ROSIGLIZATONE_TREATED_MONOCYTE_UP | 192 | 40 | 17377 | 2626 |
MIF4GD,AGRN,NF1,CDK2AP2,PMS2,PDCD7,PIP4K2A,CMTM6,FERMT3,NDUFS4,RPL23A,RBM17,NDUFA2,ZKSCAN1,BUD31,YBX1,METTL9,SLC35A1,CPNE1,TRAFD1,RPS10,LRRC8A,FBXO9,GLO1,LY6E,ISG15,HSPA1B,NECAP2,EIF3K,PON2,GNA12,DAP3,ATP1A1,JAK1,UEVLD,QARS,MRPL27,DBI,RPLP1,PSAP |
| 1.989e-02 | -3.92 | GSE36888_UNTREATED_VS_IL2_TREATED_STAT5_AB_KNOCKIN_TCELL_17H_DN | MSigDB lists | GSE36888_UNTREATED_VS_IL2_TREATED_STAT5_AB_KNOCKIN_TCELL_17H_DN | 192 | 40 | 17377 | 2626 |
USP7,PPCS,ANXA6,FAM53C,WDR13,MAGED1,TOP2B,PARK7,TFAP4,FBXL6,RBM34,CLCN6,MSH2,TTC3,CLDND1,TAGLN2,CDC25B,PTGES3,MCMBP,C12orf75,PABPC1,SPTAN1,NIPAL3,SNX2,LUC7L,SYMPK,BTBD1,ZFR,SH3BP5,PON2,FAM110A,CCDC6,EXOC4,APPL2,FKBP5,PIEZO1,SNRNP70,TAF6,PFKP,SVIP |
| 1.989e-02 | -3.92 | GSE43955_TH0_VS_TGFB_IL6_IL23_TH17_ACT_CD4_TCELL_52H_DN | MSigDB lists | GSE43955_TH0_VS_TGFB_IL6_IL23_TH17_ACT_CD4_TCELL_52H_DN | 192 | 40 | 17377 | 2626 |
ADD1,PHF23,RAC1,SMARCA4,EBNA1BP2,LANCL1,SRRT,APP,MAN1A1,CDK5,VAV1,RAP1A,CLIC4,RNFT1,DAD1,IL6ST,TBC1D14,RBM15,KDELR1,PTPN18,TMEM115,MKLN1,NCK1,AKT2,EMB,EZR,ADSL,PFKFB3,MCL1,COMMD4,LEMD2,ACYP1,PDRG1,COX7A2L,ADAM9,CHMP4B,SMAD1,B4GALT3,HIPK3,IPO4 |
| 1.989e-02 | -3.92 | GSE17721_LPS_VS_GARDIQUIMOD_4H_BMDC_UP | MSigDB lists | GSE17721_LPS_VS_GARDIQUIMOD_4H_BMDC_UP | 192 | 40 | 17377 | 2626 |
HLA-E,TOR3A,TRIO,NKD2,HMGN3,BCL2L1,BZW2,RGS1,FARSA,PCNA,RCSD1,AXIN2,TIMELESS,AP2B1,TRA2B,MDFIC,RNF19A,PLCL2,SEH1L,PHF20L1,ARHGAP17,ATP13A1,POLR2G,AKT2,ANKRD33B,SMU1,OGFR,TANC1,PSMB9,RHOB,RDH11,HLA-B,ATP6V1D,ZFP92,GADD45B,TMEM219,DTD1,NAA20,CCDC59,GEMIN7 |
| 1.989e-02 | -3.92 | GSE1925_CTRL_VS_IFNG_PRIMED_MACROPHAGE_24H_IFNG_STIM_DN | MSigDB lists | GSE1925_CTRL_VS_IFNG_PRIMED_MACROPHAGE_24H_IFNG_STIM_DN | 192 | 40 | 17377 | 2626 |
GCLM,RECQL,AGTRAP,RAE1,CDT1,RBM8A,KIF23,USP39,PMF1,CDK11B,ANKIB1,SPAG5,NUDT19,DAD1,NUP107,SUCLG2,TMEM14C,S100A6,PCBP2,PLK1,GTPBP4,ILF3,CRNKL1,MRPL16,LY6E,GAR1,CYB5A,ISG15,GEMIN5,ATP6V1D,MTHFD2,PDLIM1,PRPS2,DBI,COX7A2L,ZNF436,ACTB,CHMP4B,GAS2,IDH3B |
| 1.994e-02 | -3.91 | IL-4 Signaling Pathway | WikiPathways | WP395 | 55 | 15 | 5312 | 837 |
JAK1,SHC1,BIRC5,STAT6,NFIL3,PIK3R2,PTPN11,STAT1,ELK1,STAT3,MAPK1,MAPK14,ATF2,MAPK3,SOCS5 |
| 1.995e-02 | -3.91 | GSE45365_NK_CELL_VS_CD8A_DC_MCMV_INFECTION_DN | MSigDB lists | GSE45365_NK_CELL_VS_CD8A_DC_MCMV_INFECTION_DN | 164 | 35 | 17377 | 2626 |
TMED7,MRPL9,SYS1,PPP1R2,GSPT2,EBNA1BP2,STAM,FASTKD3,OIP5,CCNA2,COQ4,RNFT1,GMEB1,ANXA5,CLDND1,PTGES3,GEMIN4,CENPM,ALDH18A1,ZRANB1,ENPP4,ADAM17,MRS2,GMFB,SUMF2,MTMR12,CHMP2B,CCT8,NMT2,OSBPL11,PLAA,TIMM17A,CENPBD1,GEN1,SLC25A33 |
| 1.995e-02 | -3.91 | GSE26030_UNSTIM_VS_RESTIM_TH17_DAY5_POST_POLARIZATION_UP | MSigDB lists | GSE26030_UNSTIM_VS_RESTIM_TH17_DAY5_POST_POLARIZATION_UP | 164 | 35 | 17377 | 2626 |
HIVEP3,CYTIP,GPR132,PARP12,SCAMP3,RPS6KA1,MOGS,NOTCH2,CRLF3,DLG5,RINL,TBC1D14,ETV6,PPP1R12C,OSTF1,ACAD8,PLCL2,MVP,GPD1L,GM2A,PLK3,TRIM8,LDB1,LRBA,ABHD11,GALNT7,KIF2A,PFDN5,HSPBP1,BRD2,CTSA,SMAD1,TMEM159,CCDC125,HEXA |
| 1.997e-02 | -3.91 | BROWN_MYELOID_CELL_DEVELOPMENT_DN | MSigDB lists | BROWN_MYELOID_CELL_DEVELOPMENT_DN | 120 | 27 | 17377 | 2626 |
PPAN,HSPH1,HMGN1,IVNS1ABP,NSUN2,TMEM97,MFNG,GTPBP4,NUTF2,SOX4,ODC1,BZW2,TRIM28,ANKRD10,GART,SEPT1,IDE,FUT8,PGRMC1,MSH2,SLC16A1,AHCY,POLR1B,RUVBL2,F2R,MGAT5,SYTL3 |
| 2.009e-02 | -3.91 | regulation of erythrocyte differentiation | biological process | GO:0045646 | 47 | 13 | 17256 | 2622 |
SMAP1,LDB1,STAT1,KLF13,HMGB2,ETS1,LYN,MAPK14,STAT3,SENP1,FOXO3,ISG15,HSPA1B |
| 2.009e-02 | -3.91 | negative regulation of stress-activated protein kinase signaling cascade | biological process | GO:0070303 | 47 | 13 | 17256 | 2622 |
HSPH1,GPS2,FOXM1,DUSP3,ZMYND11,QARS,PBK,EZR,DNAJA1,MEN1,IGBP1,HIPK3,PDCD4 |
| 2.009e-02 | -3.91 | negative regulation of stress-activated MAPK cascade | biological process | GO:0032873 | 47 | 13 | 17256 | 2622 |
HSPH1,GPS2,FOXM1,DUSP3,ZMYND11,QARS,PBK,EZR,DNAJA1,MEN1,IGBP1,HIPK3,PDCD4 |
| 2.009e-02 | -3.91 | regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway | biological process | GO:1901028 | 47 | 13 | 17256 | 2622 |
BAK1,ATP5IF1,DYNLL1,TFDP1,E2F1,PPP3R1,BCL2,YWHAZ,TP53BP2,TFDP2,SLC25A5,TMEM14A,YWHAH |
| 2.009e-02 | -3.91 | regulation of I-kappaB kinase/NF-kappaB signaling | biological process | GO:0043122 | 225 | 46 | 17256 | 2622 |
MIB2,ASH1L,RHOC,GPR89A,SLC35B2,IRF3,UBE2I,SLC20A1,BIRC2,CFLAR,DDRGK1,TERF2IP,FKBP1A,C18orf32,NEK6,TANK,ZDHHC13,MAVS,TFG,MAP3K14,F2R,EEF1D,CPNE1,PDPK1,RHOA,BRD4,TRIM8,BIRC3,TNFAIP3,ZMYND11,MIER1,ATP2C1,USP10,UBE2V1,FADD,OPTN,TAB2,RPS27A,STAT1,CANT1,NUP62,TICAM1,TRIM32,TMEM101,PPP5C,TRAF5 |
| 2.011e-02 | -3.91 | protein deacylation | biological process | GO:0035601 | 72 | 18 | 17256 | 2622 |
PPT1,BAZ2A,MTA2,MIER1,RCOR1,MIER2,SIRT2,MBD3,BRMS1,CHD3,HDAC7,MTA1,RBBP4,SAP30L,ARID4A,LYPLA2,HDAC2,SAP30 |
| 2.011e-02 | -3.91 | vascular endothelial growth factor receptor signaling pathway | biological process | GO:0048010 | 72 | 18 | 17256 | 2622 |
WASF2,CYFIP1,RHOA,NCK1,MAPKAPK3,RAC1,VAV2,NCKAP1,CYFIP2,MAPK14,VAV1,PDCD6,CDC42,ELMO1,PIK3R2,ACTB,ROCK1,ABI1 |
| 2.011e-02 | -3.91 | - | gene3d domains | 3.40.50.800 | 11 | 5 | 8148 | 1295 |
EPRS,EIF2AK4,POLG2,HARS,TARS |
| 2.013e-02 | -3.91 | LIU_PROSTATE_CANCER_UP | MSigDB lists | LIU_PROSTATE_CANCER_UP | 88 | 21 | 17377 | 2626 |
PPP3CA,REPS2,GADD45G,PTP4A3,EIF2AK1,GALNT7,CADM1,SLC35B2,SOX4,ELK1,BZW2,SERP1,GOLM1,SLC19A1,MTHFD2,UAP1,SEL1L,CANT1,FNIP2,PDLIM5,RPL22L1 |
| 2.013e-02 | -3.91 | CHEN_LIVER_METABOLISM_QTL_CIS | MSigDB lists | CHEN_LIVER_METABOLISM_QTL_CIS | 88 | 21 | 17377 | 2626 |
PIGM,PIGN,COPA,IVNS1ABP,DCAF8,ACTR3,TOR1AIP1,TATDN3,NENF,MRPS14,USF1,UAP1,UCHL5,RABGAP1L,DBI,IARS2,CYB5R1,B4GALT3,RPS6KC1,TSEN15,IFI16 |
| 2.019e-02 | -3.90 | Translocation of GLUT4 to the plasma membrane | REACTOME pathways | R-HSA-1445148 | 62 | 17 | 10287 | 1696 |
EXOC3,KIF3B,RAB14,PRKAB1,AKT2,RAC1,RAB11A,CALM2,RAB8A,SNAP23,RAB4A,EXOC4,YWHAZ,KIFAP3,YWHAH,C2CD5,MYO5A |
| 2.022e-02 | -3.90 | TPR | smart domains | SM00028 | 126 | 27 | 9493 | 1367 |
SRP72,RPAP3,NASP,ST13,LONRF3,XAB2,WDTC1,KLC1,CDC23,TANC1,TTC33,PEX5,CDC16,TTC13,CDC27,TONSL,ZC3H7B,TTC9C,OGT,CTR9,FKBP5,TTC3,CABIN1,ANAPC7,TTC4,TTC17,PPP5C |
| 2.032e-02 | -3.90 | GSE26030_UNSTIM_VS_RESTIM_TH17_DAY5_POST_POLARIZATION_DN | MSigDB lists | GSE26030_UNSTIM_VS_RESTIM_TH17_DAY5_POST_POLARIZATION_DN | 181 | 38 | 17377 | 2626 |
PARP12,KIAA0100,SDC2,MYH9,NIPA2,SLC12A9,ETS1,REEP5,BCAT2,FKBP1A,IRF4,RAB35,ATP6V0A2,ATP6V1G1,ACSL5,SNX8,AMPD2,METTL1,NSDHL,DRAP1,LYRM1,SLC26A6,BICD2,SLC50A1,ARF4,MFN2,SLCO4A1,HGS,ATP1A1,PITPNA,ACTB,MDH1,PDXK,EHD4,PITRM1,SMURF1,ANXA11,PFKP |
| 2.032e-02 | -3.90 | GSE11057_NAIVE_VS_EFF_MEMORY_CD4_TCELL_DN | MSigDB lists | GSE11057_NAIVE_VS_EFF_MEMORY_CD4_TCELL_DN | 181 | 38 | 17377 | 2626 |
UBL3,GCLM,SMAP1,TXN,PLXNC1,CAST,FAM129A,SRGN,TOR3A,PTTG1,CDK2AP2,TMX4,CBLL1,REEP5,GSTK1,MDFIC,CLDND1,PDIA6,MYBL1,SAP30,PPIF,ELOVL5,HMGN4,LDHA,ATXN1,OGDH,EIF3A,MYO1F,FAS,SH3BP5,GOLGA7,ITGB1,CTSA,CLU,PIEZO1,MAP3K5,YWHAH,IFI16 |
| 2.032e-02 | -3.90 | GSE4142_PLASMA_CELL_VS_MEMORY_BCELL_DN | MSigDB lists | GSE4142_PLASMA_CELL_VS_MEMORY_BCELL_DN | 181 | 38 | 17377 | 2626 |
BCL2L12,MMACHC,SESTD1,ADPGK,PMF1,BCL2L1,ERH,KLF16,ATIC,DUT,PIN1,RCSD1,XRCC2,EXOSC1,NSFL1C,ORAI1,RPAP1,MRPL40,TNRC18,MND1,LONRF3,SSR2,MRPL16,RAB3IP,ARID1A,TMEM201,SUPT16H,STOML2,MRPL2,ZNF777,ORMDL2,DTD1,RUVBL2,RGL1,NAA20,MRPL13,CHID1,OAZ1 |
| 2.032e-02 | -3.90 | GSE28408_LY6G_POS_VS_NEG_DC_UP | MSigDB lists | GSE28408_LY6G_POS_VS_NEG_DC_UP | 181 | 38 | 17377 | 2626 |
NADSYN1,TRAK1,EZH1,MXD4,RGS2,RAPGEF6,RGS1,PCYOX1L,CLUAP1,ZNF75D,SP100,KLHL20,ZNF302,TNPO2,BCL2,PLK3,TNFAIP3,SNX2,ITM2A,ATP6V0A1,GLO1,MCL1,GALNT7,ANKRD46,BSDC1,RXRB,MAN2A2,AMZ2,CERS6,RPS27A,STK38,LY75,PKD2,RNASEL,NCOA1,PPP2R2D,TOB1,DDX42 |
| 2.032e-02 | -3.90 | GSE26495_NAIVE_VS_PD1HIGH_CD8_TCELL_DN | MSigDB lists | GSE26495_NAIVE_VS_PD1HIGH_CD8_TCELL_DN | 181 | 38 | 17377 | 2626 |
WSB2,GCLM,CAST,B4GALT5,FAM129A,SLC2A1,BCL2L1,GYG1,MAN1A1,JAKMIP1,WWP2,SRXN1,CAPN2,NUDT19,JAZF1,PPP4R1,MDFIC,LPCAT1,MYBL1,C12orf75,CNNM3,SYTL3,SAP30,ATXN1,ADRB2,HERPUD2,KLF6,RHBDF2,FAS,OPTN,DERL1,SH3BP5,AHNAK,HSPB11,MAP3K5,GLCCI1,CPEB2,STARD3NL |
| 2.032e-02 | -3.90 | GSE3691_IFN_PRODUCING_KILLER_DC_VS_CONVENTIONAL_DC_SPLEEN_UP | MSigDB lists | GSE3691_IFN_PRODUCING_KILLER_DC_VS_CONVENTIONAL_DC_SPLEEN_UP | 181 | 38 | 17377 | 2626 |
RMND5A,WDYHV1,TSC22D3,SF3B1,MAGED1,TRAK1,ENSA,B4GALT1,ABHD14B,RCOR3,MEX3C,CLCN6,ANP32A,GM2A,RPRD1A,NCK1,OXR1,MAP4K4,RFXANK,USP22,ARSK,EIF3H,BSDC1,GPR137,PI4K2A,PWWP2B,RAB18,MBIP,SCARB2,VPS26B,ACOX1,MAP4,OAZ2,ZFP90,ST3GAL2,ACADM,SMAD1,CABLES1 |
| 2.032e-02 | -3.90 | GSE7852_LN_VS_FAT_TCONV_UP | MSigDB lists | GSE7852_LN_VS_FAT_TCONV_UP | 181 | 38 | 17377 | 2626 |
POU3F2,FGFR1OP,DNMT3A,ZNF445,MTX3,SIKE1,ARGLU1,GGA2,SNN,SUPT7L,KIAA1147,CNOT3,C2orf68,ZER1,TFAP4,NAPG,CENPJ,HDAC7,ATP13A3,BTF3L4,AHCYL1,PIKFYVE,N4BP2,TERF2,RDH10,SLC26A6,ITM2A,PSMG1,LRP5,NCDN,TMEM41A,CERS6,STAT1,SOCS4,AEN,SNRPG,PREPL,S100PBP |
| 2.032e-02 | -3.90 | JAZAG_TGFB1_SIGNALING_UP | MSigDB lists | JAZAG_TGFB1_SIGNALING_UP | 104 | 24 | 17377 | 2626 |
SLC12A7,TIMM8B,ABHD2,PIGN,FEZ2,ILF3,TOPORS,SLC35B1,GFER,HLA-A,EBP,SUPT16H,DAP3,SEC23IP,GMEB1,BUD31,ATP6V0A2,TIMELESS,ABCD1,VPS4A,CPSF4,CNPY3,GTF2H2,STRAP |
| 2.032e-02 | -3.90 | LINDGREN_BLADDER_CANCER_CLUSTER_1_UP | MSigDB lists | LINDGREN_BLADDER_CANCER_CLUSTER_1_UP | 104 | 24 | 17377 | 2626 |
RAB14,EIF3L,RPL35,GUK1,FOXM1,CAST,TMX4,JTB,RPL6,RPL15,RPL27A,ZADH2,MAT2B,MRPL50,NT5DC1,XPA,BBX,PPP6C,ZDHHC13,FBXW2,PTPDC1,IFI16,WDR41,ATP6V1G1 |
| 2.033e-02 | -3.90 | nerve_sheath | COSMIC cancer mutations | nerve_sheath | 48 | 13 | 17385 | 2587 |
GNAS,FGFR3,RB1,EWSR1,NRAS,NF1,PTEN,ETV6,STK11,KRAS,FUS,HRAS,CDKN2A |
| 2.034e-02 | -3.90 | GNF2_TYK2 | MSigDB lists | GNF2_TYK2 | 33 | 10 | 17377 | 2626 |
CORO7,STAT6,MANBA,DDX5,ARHGDIB,ADPGK,CORO1A,MOB1A,CHD1,PAPOLA |
| 2.034e-02 | -3.90 | GO_REGULATION_OF_CELL_AGING | MSigDB lists | GO_REGULATION_OF_CELL_AGING | 33 | 10 | 17377 | 2626 |
MIF,BCL2L12,NEK6,PTEN,FOXM1,PRKDC,ARNTL,CDKN2A,LMNA,TERF2 |
| 2.034e-02 | -3.90 | GNF2_RAP1B | MSigDB lists | GNF2_RAP1B | 33 | 10 | 17377 | 2626 |
MAT2B,CYTIP,JAK1,ADAM10,HLA-E,STK38,ACTR3,CAB39,OSTF1,ADCY7 |
| 2.034e-02 | -3.90 | GO_EXTRINSIC_APOPTOTIC_SIGNALING_PATHWAY_IN_ABSENCE_OF_LIGAND | MSigDB lists | GO_EXTRINSIC_APOPTOTIC_SIGNALING_PATHWAY_IN_ABSENCE_OF_LIGAND | 33 | 10 | 17377 | 2626 |
MOAP1,BAK1,BCL2,MCL1,BCL2L1,FOXO3,APPL1,EYA2,FADD,FAS |
| 2.034e-02 | -3.90 | GO_SIGNAL_TRANSDUCTION_IN_ABSENCE_OF_LIGAND | MSigDB lists | GO_SIGNAL_TRANSDUCTION_IN_ABSENCE_OF_LIGAND | 33 | 10 | 17377 | 2626 |
MOAP1,BAK1,BCL2,MCL1,BCL2L1,FOXO3,APPL1,EYA2,FADD,FAS |
| 2.034e-02 | -3.90 | SIMBULAN_UV_RESPONSE_NORMAL_DN | MSigDB lists | SIMBULAN_UV_RESPONSE_NORMAL_DN | 33 | 10 | 17377 | 2626 |
AHNAK,TACC1,GADD45B,RBMS1,MCL1,ADRB2,PLEC,CCNF,SF3A2,POLR2A |
| 2.034e-02 | -3.90 | FRIDMAN_IMMORTALIZATION_DN | MSigDB lists | FRIDMAN_IMMORTALIZATION_DN | 33 | 10 | 17377 | 2626 |
HTATIP2,RB1,CLTB,CREG1,MAP1LC3B,HPS5,IRF5,CDKN2A,IFI16,OPTN |
| 2.034e-02 | -3.90 | GO_CELLULAR_SENESCENCE | MSigDB lists | GO_CELLULAR_SENESCENCE | 33 | 10 | 17377 | 2626 |
ULK3,NSMCE2,ARNTL,PML,H2AFX,SMC6,MAPK14,HRAS,CDKN2A,TERF2 |
| 2.036e-02 | -3.89 | COG6 (component of oligomeric golgi complex 6) | protein interactions | 57511 | 63 | 17 | 17029 | 2761 |
KIF5B,TRAPPC13,ATP6V1D,POC1A,CENPF,PTAR1,KLC1,COG1,PKD2,NCKAP1,BICD2,ARMH3,SASS6,COMMD8,ABI1,SPAG5,SNAPIN |
| 2.036e-02 | -3.89 | LPP (LIM domain containing preferred translocation partner in lipoma) | protein interactions | 4026 | 63 | 17 | 17029 | 2761 |
WDYHV1,SHPRH,VHL,SUZ12,RANGAP1,AGFG1,EFL1,ATP5MF,PICALM,CLNS1A,NPLOC4,SH3GLB1,HSPBP1,VASP,PPME1,OGT,RPRD1B |
| 2.036e-02 | -3.89 | NFYA (nuclear transcription factor Y subunit alpha) | protein interactions | 4800 | 63 | 17 | 17029 | 2761 |
CSNK2A1,BRCA1,APP,SRSF1,USF1,CCNA2,CHMP4A,UAP1,ZHX1,ATF6,TAF12,CREB1,TAF6,ATF2,USF2,CDK2,LUC7L2 |
| 2.036e-02 | -3.89 | TWF2 (twinfilin actin binding protein 2) | protein interactions | 11344 | 63 | 17 | 17029 | 2761 |
ERCC1,UBXN1,MYH9,CAPZA2,PKM,PSMD9,ERC1,MCTS1,LYAR,CAPN2,TERF2IP,PLAA,BCL7C,UHRF2,CAPZA1,ACTB,POT1 |
| 2.036e-02 | -3.89 | PMS1 (PMS1 homolog 1, mismatch repair system component) | protein interactions | 5378 | 63 | 17 | 17029 | 2761 |
CYLD,HELB,PTTG1,CUL3,CUL1,RANGAP1,RFC2,USP5,SMC3,AHNAK,MSH2,KPNA2,HRAS,PSMC1,MSH6,USP13,CDC5L |
| 2.039e-02 | -3.89 | RNA phosphodiester bond hydrolysis, endonucleolytic | biological process | GO:0090502 | 67 | 17 | 17256 | 2622 |
RPP25,AGO2,BMS1,LACTB2,RPSA,EDC3,UTP20,KRI1,DGCR8,POP7,RNASEK,RNASEL,RNASEH2A,CPSF4,RRS1,TSEN15,ZC3H3 |
| 2.040e-02 | -3.89 | endonuclease activity | molecular function | GO:0004519 | 129 | 29 | 17224 | 2647 |
RPP25,ERCC1,AGO2,PMS2,DCLRE1C,LACTB2,EDC3,MBD4,ANKLE1,RAD51C,DGCR8,TATDN2,PPP1R8,RNASEK,XRCC2,PELO,POP7,LRPPRC,XRCC3,RNASEH2A,RNASEL,TATDN1,CPSF4,GEN1,N4BP2,OGG1,TSEN15,ZC3H3,RAD51D |
| 2.040e-02 | -3.89 | hydrolase activity, acting on glycosyl bonds | molecular function | GO:0016798 | 129 | 29 | 17224 | 2647 |
NAGPA,GALC,MANBA,MAN1B1,GNE,HEXB,MOGS,GBA,USF3,MAN2B1,EDEM2,MPG,NEIL2,NEU1,MAN1A1,MBD4,MAN2A2,PCNA,PARG,NEIL3,CTBS,NAGLU,DNPH1,CTSA,PSAP,HEXA,CHID1,OGG1,GM2A |
| 2.045e-02 | -3.89 | acylglycerol O-acyltransferase activity | molecular function | GO:0016411 | 28 | 9 | 17224 | 2647 |
AGPAT2,LPCAT4,AGPAT1,AGPAT3,MBOAT1,LCLAT1,LPCAT1,TAZ,ABHD5 |
| 2.045e-02 | -3.89 | nuclear localization sequence binding | molecular function | GO:0008139 | 28 | 9 | 17224 | 2647 |
KPNA4,KPNA1,TNPO3,BRAP,TNPO2,KPNA2,NUP153,NUP58,IPO4 |
| 2.046e-02 | -3.89 | histone H4 acetylation | biological process | GO:0043967 | 52 | 14 | 17256 | 2622 |
IRF4,KAT2A,KAT7,NAA50,OGT,ELP4,KANSL2,RUVBL2,USP22,BEND3,NCOA1,WDR5,NAA60,MEAF6 |
| 2.046e-02 | -3.89 | MICOS complex | cellular component | GO:0061617 | 8 | 4 | 18223 | 2701 |
CHCHD3,IMMT,APOOL,CHCHD6 |
| 2.046e-02 | -3.89 | F-actin capping protein complex | cellular component | GO:0008290 | 8 | 4 | 18223 | 2701 |
CAPZA2,ADD1,MTPN,CAPZA1 |
| 2.046e-02 | -3.89 | Cdc73/Paf1 complex | cellular component | GO:0016593 | 8 | 4 | 18223 | 2701 |
PAF1,CTR9,RTF1,CDC73 |
| 2.046e-02 | -3.89 | SMAD protein complex | cellular component | GO:0071141 | 8 | 4 | 18223 | 2701 |
DDX5,SMAD2,SMAD1,SMAD4 |
| 2.057e-02 | -3.88 | protein deacetylation | biological process | GO:0006476 | 62 | 16 | 17256 | 2622 |
BAZ2A,MTA2,MIER1,RCOR1,MIER2,SIRT2,MBD3,BRMS1,CHD3,HDAC7,MTA1,RBBP4,SAP30L,HDAC2,ARID4A,SAP30 |
| 2.057e-02 | -3.88 | U2 snRNP | cellular component | GO:0005686 | 20 | 7 | 18223 | 2701 |
SNRPG,SNRPD3,SNRPB,SF3A2,SF3B1,SF3B6,SF3B2 |
| 2.057e-02 | -3.88 | chaperone complex | cellular component | GO:0101031 | 20 | 7 | 18223 | 2701 |
CCT2,TSC1,PTGES3,PPP5C,CCT8,BBS12,CDC37 |
| 2.064e-02 | -3.88 | GO_GLUCOSAMINE_CONTAINING_COMPOUND_METABOLIC_PROCESS | MSigDB lists | GO_GLUCOSAMINE_CONTAINING_COMPOUND_METABOLIC_PROCESS | 24 | 8 | 17377 | 2626 |
AMDHD2,GNPNAT1,NANP,GNPDA1,CHID1,GNE,CTBS,OGT |
| 2.064e-02 | -3.88 | GO_REGULATION_OF_HISTONE_H3_K4_METHYLATION | MSigDB lists | GO_REGULATION_OF_HISTONE_H3_K4_METHYLATION | 24 | 8 | 17377 | 2626 |
ZNF335,OGT,CTR9,H2AFY,RTF1,BRCA1,SMAD4,DNMT1 |
| 2.064e-02 | -3.88 | BIOCARTA_ECM_PATHWAY | MSigDB lists | BIOCARTA_ECM_PATHWAY | 24 | 8 | 17377 | 2626 |
RHOA,SHC1,RAF1,ITGB1,ROCK1,MAPK1,HRAS,MAPK3 |
| 2.064e-02 | -3.88 | KYNG_ENVIRONMENTAL_STRESS_RESPONSE_NOT_BY_UV_IN_OLD | MSigDB lists | KYNG_ENVIRONMENTAL_STRESS_RESPONSE_NOT_BY_UV_IN_OLD | 24 | 8 | 17377 | 2626 |
CSDE1,EIF3L,GALNT2,CCNL2,GNPNAT1,RHOB,SOCS4,FLOT1 |
| 2.064e-02 | -3.88 | MAGRANGEAS_MULTIPLE_MYELOMA_IGG_VS_IGA_DN | MSigDB lists | MAGRANGEAS_MULTIPLE_MYELOMA_IGG_VS_IGA_DN | 24 | 8 | 17377 | 2626 |
RAP1A,CSK,DAP,PELO,PSMB7,ACTB,GLUD1,BRCA1 |
| 2.064e-02 | -3.88 | GO_NUCLEOTIDE_EXCISION_REPAIR_DNA_GAP_FILLING | MSigDB lists | GO_NUCLEOTIDE_EXCISION_REPAIR_DNA_GAP_FILLING | 24 | 8 | 17377 | 2626 |
RPA2,PCNA,RFC3,POLE,POLK,RPS27A,RFC2,RPA1 |
| 2.064e-02 | -3.88 | GO_RETROGRADE_TRANSPORT_VESICLE_RECYCLING_WITHIN_GOLGI | MSigDB lists | GO_RETROGRADE_TRANSPORT_VESICLE_RECYCLING_WITHIN_GOLGI | 24 | 8 | 17377 | 2626 |
COG1,PACS1,GCC2,GOLGA4,RAB6A,SYS1,GCC1,OPTN |
| 2.064e-02 | -3.88 | REACTOME_DARPP_32_EVENTS | MSigDB lists | REACTOME_DARPP_32_EVENTS | 24 | 8 | 17377 | 2626 |
CDK5,CALM2,PPP2CA,PPP3CA,PRKAR1B,PPP3R1,PPP3CB,PRKACA |
| 2.064e-02 | -3.88 | TOMIDA_METASTASIS_UP | MSigDB lists | TOMIDA_METASTASIS_UP | 24 | 8 | 17377 | 2626 |
ALG3,GNAS,PSMD2,GNAI2,DAD1,PTTG1,ECH1,TUBB |
| 2.064e-02 | -3.88 | GO_PROTEIN_DEPOLYMERIZATION | MSigDB lists | GO_PROTEIN_DEPOLYMERIZATION | 24 | 8 | 17377 | 2626 |
KIF18A,KIF18B,KIF14,VPS4A,KIF2C,STMN1,CFL1,MICAL3 |
| 2.064e-02 | -3.88 | GO_NEGATIVE_REGULATION_OF_VIRAL_TRANSCRIPTION | MSigDB lists | GO_NEGATIVE_REGULATION_OF_VIRAL_TRANSCRIPTION | 24 | 8 | 17377 | 2626 |
TFAP4,TRIM8,SP100,ZNF639,TRIM11,TARDBP,TRIM32,TRIM14 |
| 2.064e-02 | -3.88 | MODULE_155 | MSigDB lists | MODULE_155 | 24 | 8 | 17377 | 2626 |
SSR2,FKBP1A,KPNA2,ATF6,DNAJA1,PDIA6,KDELR1,SSR1 |
| 2.069e-02 | -3.88 | GEMIN6 (gem nuclear organelle associated protein 6) | protein interactions | 79833 | 31 | 10 | 17029 | 2761 |
GEMIN5,SNRPB,DDX20,GEMIN4,SNRPG,SNRPD3,SNRNP70,STRAP,CDC5L,GEMIN7 |
| 2.069e-02 | -3.88 | BCL11A (B cell CLL/lymphoma 11A) | protein interactions | 53335 | 31 | 10 | 17029 | 2761 |
PHF20L1,MTA1,MTA2,CDCA3,NR2F2,UBE2I,MBD3,APP,HDAC2,ZBTB24 |
| 2.069e-02 | -3.88 | MRPL51 (mitochondrial ribosomal protein L51) | protein interactions | 51258 | 31 | 10 | 17029 | 2761 |
MRPL50,MRPL9,MRPL42,MRPL55,MRPL39,MRPL12,LAMTOR3,MPV17,MRPL40,MRPL21 |
| 2.069e-02 | -3.88 | MAGOHB (mago homolog B, exon junction complex core component) | protein interactions | 55110 | 31 | 10 | 17029 | 2761 |
TERF2IP,GOLGA2,MCM2,CDK2,ZMYND11,HMG20A,RBMX,DVL2,RBM8A,TERF2 |
| 2.069e-02 | -3.88 | STMN2 (stathmin 2) | protein interactions | 11075 | 31 | 10 | 17029 | 2761 |
PPM1G,TXLNA,SMARCA4,UBE2I,AHCYL1,IGBP1,PRKACA,STAM,SSSCA1,MAPK3 |
| 2.069e-02 | -3.88 | CD27 (CD27 molecule) | protein interactions | 939 | 31 | 10 | 17029 | 2761 |
CD59,C1GALT1,SIVA1,ADCY9,SLC25A51,UHRF2,TRAF5,HRAS,BIRC2,GNB2 |
| 2.069e-02 | -3.88 | MBOAT1 (membrane bound O-acyltransferase domain containing 1) | protein interactions | 154141 | 31 | 10 | 17029 | 2761 |
DERL1,HSPA4,ATP1A1,SCAMP3,ATP2A2,TAP1,LTN1,ATP5F1B,ATP5F1A,TECR |
| 2.069e-02 | -3.88 | DUSP28 (dual specificity phosphatase 28) | protein interactions | 285193 | 31 | 10 | 17029 | 2761 |
SRM,DHPS,ARF5,DCTN2,CBWD1,TAGLN2,ICMT,DUSP22,PARK7,CBX3 |
| 2.069e-02 | -3.88 | CAMKK1 (calcium/calmodulin dependent protein kinase kinase 1) | protein interactions | 84254 | 31 | 10 | 17029 | 2761 |
NSA2,FBXL6,TRIM11,PRKAA1,RPS10,RUVBL2,H3F3A,SAFB2,APP,DDB1 |
| 2.069e-02 | -3.88 | SLU7 (SLU7 homolog, splicing factor) | protein interactions | 10569 | 31 | 10 | 17029 | 2761 |
ZCCHC10,GOLGA2,PPIG,RBM8A,JMJD6,NSD3,PRPF3,LMNA,PCBP2,SF3B2 |
| 2.069e-02 | -3.88 | AKAP13 (A-kinase anchoring protein 13) | protein interactions | 11214 | 31 | 10 | 17029 | 2761 |
BAK1,GNA12,RHOA,YWHAZ,PRKACA,MTR,APP,RXRB,RTKN,SRPK2 |
| 2.069e-02 | -3.88 | ESD (esterase D) | protein interactions | 2098 | 31 | 10 | 17029 | 2761 |
PDCD6IP,RAE1,DDA1,TKT,MDH1,GYG1,GPI,PITPNB,NANP,OAT |
| 2.069e-02 | -3.88 | OXA1L (OXA1L, mitochondrial inner membrane protein) | protein interactions | 5018 | 31 | 10 | 17029 | 2761 |
MRPL50,SDHB,NDUFA4,ATP5F1B,MRPL48,IKBIP,TOMM40,RHOT2,MRPL13,EYA2 |
| 2.069e-02 | -3.88 | Ppp4c (protein phosphatase 4, catalytic subunit) | protein interactions | 56420 | 31 | 10 | 17029 | 2761 |
MAGED2,CCT2,NAP1L1,CCDC6,BANF1,PPP4R1,NARF,IGBP1,GAR1,CCT8 |
| 2.069e-02 | -3.88 | WASHC4 (WASH complex subunit 4) | protein interactions | 23325 | 31 | 10 | 17029 | 2761 |
RPA2,SNRNP200,SMAD2,VPS26B,WDHD1,CSNK2A1,CAPZA2,ROCK1,RPA1,USP34 |
| 2.069e-02 | -3.88 | DCAF13 (DDB1 and CUL4 associated factor 13) | protein interactions | 25879 | 31 | 10 | 17029 | 2761 |
UTP20,DDX47,TK1,TBL3,KBTBD7,KRAS,NDE1,FBL,IFI16,DDB1 |
| 2.069e-02 | -3.88 | HNRNPA1L2 (heterogeneous nuclear ribonucleoprotein A1-like 2) | protein interactions | 144983 | 31 | 10 | 17029 | 2761 |
COX15,MCM5,HNRNPH3,KIF14,STX18,HNRNPF,RAB1A,MCM2,PARK7,LMNA |
| 2.069e-02 | -3.88 | ARID2 (AT-rich interaction domain 2) | protein interactions | 196528 | 31 | 10 | 17029 | 2761 |
TFAP4,KPNA1,VHL,BCL7C,SMARCA4,RRM2,BRD7,PBRM1,SMARCE1,SMARCD1 |
| 2.069e-02 | -3.88 | MAGT1 (magnesium transporter 1) | protein interactions | 84061 | 31 | 10 | 17029 | 2761 |
PPIB,SEC61A1,DDOST,RPL6,VDAC2,COX4I1,TECR,VDAC1,EVC2,SSR1 |
| 2.070e-02 | -3.88 | cytochrome complex | cellular component | GO:0070069 | 29 | 9 | 18223 | 2701 |
COX15,COX5B,UQCR10,COX8A,COX5A,UQCRH,COX4I1,NDUFA4,CYC1 |
| 2.072e-02 | -3.88 | NCDN (neurochondrin) | protein interactions | 23154 | 49 | 14 | 17029 | 2761 |
RPN1,ATP1A1,SEC61A1,PPP1R2,MOGS,PGRMC1,ASAH1,ECD,ATP5F1B,ESYT1,ATP5F1A,POT1,GINS4,NCDN |
| 2.072e-02 | -3.88 | ARL6IP1 (ADP ribosylation factor like GTPase 6 interacting protein 1) | protein interactions | 23204 | 49 | 14 | 17029 | 2761 |
C12orf10,UNK,HGS,GOLPH3L,SNX15,TUFM,ARL6IP1,ZFYVE21,GORASP2,WIPI2,ACSF2,NUDT3,LMNA,FDFT1 |
| 2.072e-02 | -3.88 | ARHGAP17 (Rho GTPase activating protein 17) | protein interactions | 55114 | 49 | 14 | 17029 | 2761 |
EWSR1,CDC42,SH3BP1,TRIP10,ACTR3,RAC1,CAPZA1,KLC1,ARRB2,CHMP7,COMMD4,APP,PARD3,SH3GLB1 |
| 2.072e-02 | -3.88 | FZD10 (frizzled class receptor 10) | protein interactions | 11211 | 49 | 14 | 17029 | 2761 |
THADA,BTAF1,ATP6V0A1,INTS12,TNPO3,ATP6V0A2,TNPO2,SMC2,GEMIN4,GSTCD,XPO7,NCAPG,CIP2A,EBP |
| 2.072e-02 | -3.88 | Fgfr1op (Fgfr1 oncogene partner) | protein interactions | 75296 | 49 | 14 | 17029 | 2761 |
PPP2CA,RAB14,FGFR1OP,CCDC57,MCM10,PCM1,CCDC138,CCDC14,FOPNL,RAB7A,VDAC2,KIAA1328,SHCBP1,CSNK1D |
| 2.072e-02 | -3.88 | NRAS (NRAS proto-oncogene, GTPase) | protein interactions | 4893 | 49 | 14 | 17029 | 2761 |
AFDN,SHOC2,GOLGA7,NF1,RAF1,SRI,RACGAP1,BCL2,DNAJB1,ICMT,SMAD4,BZW2,ABHD5,PAPOLA |
| 2.072e-02 | -3.88 | SLC2A4 (solute carrier family 2 member 4) | protein interactions | 6517 | 49 | 14 | 17029 | 2761 |
NSF,AKT2,ARF5,RAB7A,ACOX1,CRNKL1,AP1M1,SDF2L1,MVP,UBE2I,PDIA6,CFL1,SMAP2,ESYT2 |
| 2.072e-02 | -3.88 | ALKBH3 (alkB homolog 3, alpha-ketoglutaratedependent dioxygenase) | protein interactions | 221120 | 49 | 14 | 17029 | 2761 |
USP7,CCT2,GOLGA2,KRAS,BCLAF1,THRAP3,GLRX3,CCT8,MATR3,DHX15,TUBB,CLNS1A,SF3B2,SRPK2 |
| 2.072e-02 | -3.88 | CHTOP (chromatin target of PRMT1) | protein interactions | 26097 | 49 | 14 | 17029 | 2761 |
FYTTD1,ERH,COX15,SARNP,THOC1,EIF4A3,SUZ12,BCLAF1,VDAC1,PARK7,APP,POC5,DCTN1,SRPK2 |
| 2.072e-02 | -3.88 | Ribosomal_L2_C | smart domains | SM01382 | 2 | 2 | 9493 | 1367 |
MRPL2,RPL8 |
| 2.072e-02 | -3.88 | Ribosomal_L2 | smart domains | SM01383 | 2 | 2 | 9493 | 1367 |
MRPL2,RPL8 |
| 2.072e-02 | -3.88 | CoA_binding | smart domains | SM00881 | 2 | 2 | 9493 | 1367 |
SUCLG1,ACLY |
| 2.072e-02 | -3.88 | PSP | smart domains | SM00581 | 2 | 2 | 9493 | 1367 |
ZCCHC8,SF3B2 |
| 2.072e-02 | -3.88 | Cdc6_C | smart domains | SM01074 | 2 | 2 | 9493 | 1367 |
CDC6,ORC1 |
| 2.072e-02 | -3.88 | eIF2B_5 | smart domains | SM00653 | 2 | 2 | 9493 | 1367 |
EIF2S2,EIF5 |
| 2.072e-02 | -3.88 | RPOL4c | smart domains | SM00657 | 2 | 2 | 9493 | 1367 |
CRCP,POLR2D |
| 2.072e-02 | -3.88 | SFM | smart domains | SM00500 | 2 | 2 | 9493 | 1367 |
PRPF4,PRPF18 |
| 2.072e-02 | -3.88 | RPOL9 | smart domains | SM00661 | 2 | 2 | 9493 | 1367 |
POLR2I,POLR3K |
| 2.072e-02 | -3.88 | Rtt106 | smart domains | SM01287 | 2 | 2 | 9493 | 1367 |
SUPT16H,SSRP1 |
| 2.074e-02 | -3.88 | Neurotrophin signaling pathway | KEGG pathways | hsa04722 | 119 | 28 | 7161 | 1149 |
PDPK1,RHOA,NRAS,RAF1,RPS6KA1,AKT2,RAC1,MAGED1,KRAS,ARHGDIB,MAPK14,PSEN1,FOXO3,MAP2K2,MAPK3,CALM2,CRKL,RAP1A,CDC42,SHC1,PIK3R2,PRDM4,PTPN11,BCL2,MAP3K5,MAPK1,HRAS,CAMK2G |
| 2.074e-02 | -3.88 | Neurotrophin signaling pathway | KEGG pathways | ko04722 | 119 | 28 | 7161 | 1149 |
PDPK1,RHOA,NRAS,RAF1,RPS6KA1,AKT2,RAC1,MAGED1,KRAS,ARHGDIB,MAPK14,PSEN1,FOXO3,MAP2K2,MAPK3,CALM2,CRKL,RAP1A,CDC42,SHC1,PIK3R2,PRDM4,PTPN11,BCL2,MAP3K5,MAPK1,HRAS,CAMK2G |
| 2.074e-02 | -3.88 | lichen_sclerosus | COSMIC cancer mutations | lichen_sclerosus | 8 | 4 | 17385 | 2587 |
KRAS,NRAS,HRAS,CDKN2A |
| 2.074e-02 | -3.88 | stomach-carcinoma-papillary_adenocarcinoma | COSMIC cancer mutations | stomach-carcinoma-papillary_adenocarcinoma | 8 | 4 | 17385 | 2587 |
KRAS,NRAS,HRAS,MSH6 |
| 2.074e-02 | -3.88 | cervix-in_situ_neoplasm-cervical_intraepithelial_neoplasia_Grade_I | COSMIC cancer mutations | cervix-in_situ_neoplasm-cervical_intraepithelial_neoplasia_Grade_I | 8 | 4 | 17385 | 2587 |
FGFR3,NRAS,HRAS,CDKN2A |
| 2.074e-02 | -3.88 | salivary_gland-parotid-carcinoma-mucoepidermoid_carcinoma | COSMIC cancer mutations | salivary_gland-parotid-carcinoma-mucoepidermoid_carcinoma | 8 | 4 | 17385 | 2587 |
KRAS,EWSR1,HRAS,CDKN2A |
| 2.074e-02 | -3.88 | eye-malignant_melanoma | COSMIC cancer mutations | eye-malignant_melanoma | 8 | 4 | 17385 | 2587 |
EWSR1,NRAS,PTEN,CDKN2A |
| 2.074e-02 | -3.88 | cervical_intraepithelial_neoplasia_Grade_I | COSMIC cancer mutations | cervical_intraepithelial_neoplasia_Grade_I | 8 | 4 | 17385 | 2587 |
FGFR3,NRAS,HRAS,CDKN2A |
| 2.074e-02 | -3.88 | vulva-other-lichen_sclerosus | COSMIC cancer mutations | vulva-other-lichen_sclerosus | 8 | 4 | 17385 | 2587 |
KRAS,NRAS,HRAS,CDKN2A |
| 2.074e-02 | -3.88 | bone-sarcoma | COSMIC cancer mutations | bone-sarcoma | 8 | 4 | 17385 | 2587 |
KRAS,NRAS,SF3B1,HRAS |
| 2.074e-02 | -3.88 | endometrium-carcinoma-small_cell_carcinoma | COSMIC cancer mutations | endometrium-carcinoma-small_cell_carcinoma | 8 | 4 | 17385 | 2587 |
KRAS,NRAS,PTEN,HRAS |
| 2.074e-02 | -3.88 | penis-carcinoma | COSMIC cancer mutations | penis-carcinoma | 8 | 4 | 17385 | 2587 |
KRAS,NRAS,PTEN,HRAS |
| 2.074e-02 | -3.88 | autonomic_ganglia-extraadrenal-paraganglioma | COSMIC cancer mutations | autonomic_ganglia-extraadrenal-paraganglioma | 8 | 4 | 17385 | 2587 |
KRAS,MAX,MEN1,VHL |
| 2.074e-02 | -3.88 | papillary_adenocarcinoma | COSMIC cancer mutations | papillary_adenocarcinoma | 8 | 4 | 17385 | 2587 |
KRAS,NRAS,HRAS,MSH6 |
| 2.074e-02 | -3.88 | salivary_gland-parotid-adenoma-pleomorphic | COSMIC cancer mutations | salivary_gland-parotid-adenoma-pleomorphic | 8 | 4 | 17385 | 2587 |
KRAS,NRAS,HRAS,CDKN2A |
| 2.074e-02 | -3.88 | ovary-germ_cell_tumour | COSMIC cancer mutations | ovary-germ_cell_tumour | 8 | 4 | 17385 | 2587 |
KRAS,NRAS,HRAS,CDKN2A |
| 2.074e-02 | -3.88 | testis-sex_cord-stromal_tumour-Leydig_cell_tumour | COSMIC cancer mutations | testis-sex_cord-stromal_tumour-Leydig_cell_tumour | 8 | 4 | 17385 | 2587 |
GNAS,KRAS,NRAS,HRAS |
| 2.074e-02 | -3.88 | testis-germ_cell_tumour-yolk_sac_tumour | COSMIC cancer mutations | testis-germ_cell_tumour-yolk_sac_tumour | 8 | 4 | 17385 | 2587 |
KRAS,NRAS,HRAS,CDKN2A |
| 2.074e-02 | -3.88 | paranasal_sinus | COSMIC cancer mutations | paranasal_sinus | 8 | 4 | 17385 | 2587 |
KRAS,NRAS,PTEN,HRAS |
| 2.074e-02 | -3.88 | central_nervous_system-posterior_fossa-glioma-astrocytoma_Grade_III | COSMIC cancer mutations | central_nervous_system-posterior_fossa-glioma-astrocytoma_Grade_III | 8 | 4 | 17385 | 2587 |
H3F3A,CDKN2A,MSH6,MSH2 |
| 2.074e-02 | -3.88 | Leydig_cell_tumour | COSMIC cancer mutations | Leydig_cell_tumour | 8 | 4 | 17385 | 2587 |
GNAS,KRAS,NRAS,HRAS |
| 2.074e-02 | -3.88 | bone-tibia-osteosarcoma | COSMIC cancer mutations | bone-tibia-osteosarcoma | 8 | 4 | 17385 | 2587 |
RB1,H3F3A,SF3B1,CDKN2A |
| 2.074e-02 | -3.88 | placenta-choriocarcinoma | COSMIC cancer mutations | placenta-choriocarcinoma | 8 | 4 | 17385 | 2587 |
KRAS,NRAS,SF3B1,HRAS |
| 2.074e-02 | -3.88 | endometrium-carcinoma-mucinous_carcinoma | COSMIC cancer mutations | endometrium-carcinoma-mucinous_carcinoma | 8 | 4 | 17385 | 2587 |
KRAS,NRAS,HRAS,CDKN2A |
| 2.074e-02 | -3.88 | upper_aerodigestive_tract-trachea-carcinoma-adenoid_cystic_carcinoma | COSMIC cancer mutations | upper_aerodigestive_tract-trachea-carcinoma-adenoid_cystic_carcinoma | 8 | 4 | 17385 | 2587 |
KRAS,NRAS,PTEN,HRAS |
| 2.080e-02 | -3.87 | RNA polymerase II transcription factor binding | molecular function | GO:0001085 | 140 | 31 | 17224 | 2647 |
ERCC1,CTDP1,IFRD1,MTA2,LDB1,DHX9,MEF2A,MEF2D,TAF6L,ELK1,MAD2L2,DDRGK1,WWP2,RB1,RBL1,MTA1,SETD3,HIPK2,ZNHIT6,PITX1,RBPJ,RUVBL2,TAF12,FBL,YY1,CREB1,TAF6,STAT3,ATF2,SMAD4,HDAC2 |
| 2.085e-02 | -3.87 | GO_HYDROLASE_ACTIVITY_ACTING_ON_GLYCOSYL_BONDS | MSigDB lists | GO_HYDROLASE_ACTIVITY_ACTING_ON_GLYCOSYL_BONDS | 115 | 26 | 17377 | 2626 |
NAGPA,GALC,MANBA,GNE,MAN1B1,HEXB,MOGS,GBA,MAN2B1,MPG,EDEM2,NEU1,NEIL2,MAN1A1,MBD4,MAN2A2,PCNA,PARG,NEIL3,CTBS,NAGLU,CTSA,HEXA,OGG1,CHID1,GM2A |
| 2.089e-02 | -3.87 | Serotonin Receptor 4/6/7 and NR3C Signaling | WikiPathways | WP734 | 19 | 7 | 5312 | 837 |
GNAS,RAP1A,CREB1,ELK1,MAPK1,MAP2K2,MAPK3 |
| 2.089e-02 | -3.87 | IL-9 Signaling Pathway | WikiPathways | WP22 | 19 | 7 | 5312 | 837 |
JAK1,STAT3,MAPK1,MAP2K2,PIK3R2,MAPK3,STAT1 |
| 2.090e-02 | -3.87 | Methionine salvage pathway | KEGG pathways | hsa_M00034 | 11 | 5 | 7161 | 1149 |
MAT2B,SRM,MRI1,AMD1,MAT2A |
| 2.090e-02 | -3.87 | Methionine salvage pathway | KEGG pathways | M00034 | 11 | 5 | 7161 | 1149 |
MAT2B,SRM,MRI1,AMD1,MAT2A |
| 2.091e-02 | -3.87 | negative regulation of organelle organization | biological process | GO:0010639 | 341 | 66 | 17256 | 2622 |
ZNF207,WASF2,ANKRD27,CHMP2A,FEZ2,TSC2,ADD1,PTTG1,BCL2L1,STMN1,BECN1,TWF2,TERF2IP,NOC2L,DNM2,CORO1A,LMAN1,DNMT1,HTRA2,PLK1,PPIF,ERCC1,RAB7A,GMFB,BRCA1,CCNF,MCM2,SLC25A5,MID1IP1,WAS,CHMP4A,MAP4,CHMP4B,CLU,H3F3A,ARRB2,POT1,SMAD4,MAPRE1,GMFG,TRIP12,PHF23,MECP2,CENPF,CIB1,MAD2L2,LMNA,FBXO5,TIGAR,CCP110,CAPZA1,MSH2,ARHGEF2,H2AFY,SPTAN1,TERF2,KAT2A,CAMSAP1,CAPZA2,KDM3A,XRCC5,ATAD2,ARAP1,TMEM14A,TERF1,ESPL1 |
| 2.094e-02 | -3.87 | GSE14308_TH2_VS_TH1_DN | MSigDB lists | GSE14308_TH2_VS_TH1_DN | 187 | 39 | 17377 | 2626 |
MIB2,SEPHS2,ZNF207,TOR3A,GSPT2,C5orf30,UCK1,AGFG1,CPNE3,MXD1,ANKRD28,ABL2,CLUAP1,C1GALT1,THAP4,TTC9C,ZNF260,PPCDC,TTLL12,CITED2,MORC3,KLF10,LRRC8A,EMP3,MAP7D1,ABHD11,FAM133B,MEF2D,ICAM2,ARSK,JAK1,GOLGA7,TTLL4,RBL1,WIPI2,AKNA,PDLIM5,MAPK1,ZBTB11 |
| 2.094e-02 | -3.87 | GSE17721_0.5H_VS_4H_POLYIC_BMDC_DN | MSigDB lists | GSE17721_0.5H_VS_4H_POLYIC_BMDC_DN | 187 | 39 | 17377 | 2626 |
DLGAP4,CHIC2,NIPA2,ORC1,ZADH2,STAM,SRXN1,ANKRD26,PCNA,IL6ST,SOCS6,ATP6V0A2,OSTF1,CLDND1,TECR,GCC1,DRAM2,STAU1,USO1,BAZ2A,NET1,PARP4,PACS1,PRPF3,NDUFA7,GOSR1,CCDC127,OSBPL11,KEAP1,PPP2R5A,CCDC6,STX18,TFDP1,ZNF436,ATE1,USP11,PDLIM5,GLCCI1,HIPK3 |
| 2.094e-02 | -3.87 | GSE369_PRE_VS_POST_IL6_INJECTION_IFNG_KO_LIVER_DN | MSigDB lists | GSE369_PRE_VS_POST_IL6_INJECTION_IFNG_KO_LIVER_DN | 187 | 39 | 17377 | 2626 |
LIME1,GNPNAT1,TMEM184B,ANXA6,HJURP,GPR89A,SLC2A1,CREBL2,MXD4,DNAJB1,RUFY1,TRIM65,JMY,KIAA1147,PAPOLA,ZNF428,UBXN2A,IL6ST,CTR9,ABCC1,PTPRK,POU2AF1,TSHZ1,TCTEX1D2,PRKDC,ITM2A,TOR1AIP2,LRRC1,DNAJA1,PRMT2,PRPSAP1,PDE3B,GEMIN5,TMEM41A,FBXO28,DUSP11,GALNT10,MAP3K5,GPR89B |
| 2.094e-02 | -3.87 | GSE26156_DOUBLE_POSITIVE_VS_CD4_SINGLE_POSITIVE_THYMOCYTE_UP | MSigDB lists | GSE26156_DOUBLE_POSITIVE_VS_CD4_SINGLE_POSITIVE_THYMOCYTE_UP | 187 | 39 | 17377 | 2626 |
HLA-E,TSC22D3,DNAJB2,SRSF6,UBXN1,TRIO,BTN3A1,DAZAP2,RGS1,RPL11,CREM,ADD3,ITGB8,ADCY9,JOSD1,PIK3IP1,TIPARP,ATP6V1G1,CYTH1,RPL29,KAT2A,BTG2,KAT7,CIRBP,RPL38,CYFIP2,STX16,TAZ,EIF3G,RBM38,RPL37,PFDN5,TRAM2,RPL32,RPS27A,GADD45B,PPP6R2,TERF1,RNF139 |
| 2.094e-02 | -3.87 | EGFR_UP.V1_DN | MSigDB lists | EGFR_UP.V1_DN | 187 | 39 | 17377 | 2626 |
NDUFA5,DEPDC1,CASP6,TSC22D3,ANK3,ZNF107,RUFY1,METTL3,NUP205,DTL,RFWD3,FANCL,PRKD3,ADD3,BDH1,GPATCH1,LTN1,BCL2,SGCB,ENPP4,RPP25,CDKN2AIP,ELOVL5,DCAF6,RHOBTB3,CELSR2,SIGMAR1,GALC,NET1,WIPF1,CADM1,KIF11,KRIT1,GOLGA8A,SH3GLB2,TAF12,TSPAN5,POT1,PDCD4 |
| 2.094e-02 | -3.87 | GSE2770_UNTREATED_VS_IL4_TREATED_ACT_CD4_TCELL_6H_UP | MSigDB lists | GSE2770_UNTREATED_VS_IL4_TREATED_ACT_CD4_TCELL_6H_UP | 187 | 39 | 17377 | 2626 |
PTMS,LYRM4,TRIM11,CDK2AP2,DCTN2,ARID5A,STARD7,RAB23,SLC29A1,EZH1,STMN1,PIP4K2A,SPPL2A,FBXO3,GNS,RNASEK,SRI,FBXW2,MVP,MTPN,ATP6V0D1,SEH1L,RDH10,ZMYM5,RRM2,FBXO9,GALNT7,PTTG1IP,RHOT2,ABCF1,RHOB,TBC1D17,VPS26B,OAZ2,CLU,CLN3,SMAD1,RNF14,PURA |
| 2.094e-02 | -3.87 | GSE17721_POLYIC_VS_PAM3CSK4_24H_BMDC_UP | MSigDB lists | GSE17721_POLYIC_VS_PAM3CSK4_24H_BMDC_UP | 187 | 39 | 17377 | 2626 |
POU3F2,COX15,MCM10,PARP12,SYS1,SECISBP2,THRAP3,RRP36,PIP5K1C,CFLAR,GTF2F1,APLP2,ATG3,ARL6IP1,GPATCH1,ARHGEF2,INTS12,CPNE1,CSNK1G2,CSRP1,BAZ2A,SEPT8,NEU1,RXRB,PI4K2A,BRWD1,CSK,LUC7L3,FAM3C,RNF38,LY75,PITPNA,DDX5,TRIM32,TCOF1,NAA20,PLOD3,FAU,NUMB |
| 2.094e-02 | -3.87 | GSE557_CIITA_KO_VS_I_AB_KO_DC_UP | MSigDB lists | GSE557_CIITA_KO_VS_I_AB_KO_DC_UP | 187 | 39 | 17377 | 2626 |
PPIB,NAT9,GMFG,AGRN,HLA-E,B4GALT5,DNAJB2,C5orf30,SMC6,CREBL2,RAPGEF6,APP,HMG20A,RHBDD1,DDRGK1,TMCC3,TBC1D14,XPA,PPCDC,SRI,RP2,PDLIM2,ZNF524,ETV3,MAPKAPK3,PBXIP1,LRRC8A,ATXN1,ABHD11,EDEM2,HLA-B,TBC1D17,HSPB11,PDLIM1,CAMKMT,MPV17,DUSP11,IGBP1,PDLIM5 |
| 2.095e-02 | -3.87 | BIR | pfam domains | PF00653 | 8 | 4 | 17054 | 2545 |
BIRC3,BIRC5,BIRC2,XIAP |
| 2.095e-02 | -3.87 | NIF | pfam domains | PF03031 | 8 | 4 | 17054 | 2545 |
CTDP1,CTDSP2,TIMM50,UBLCP1 |
| 2.095e-02 | -3.87 | PIP5K | pfam domains | PF01504 | 8 | 4 | 17054 | 2545 |
PIKFYVE,PIP4K2A,PIP5K1C,PIP4K2C |
| 2.096e-02 | -3.87 | positive regulation of transferase activity | biological process | GO:0051347 | 663 | 120 | 17256 | 2622 |
CCNC,KARS,TXN,TRAF7,MAP3K7CL,RAF1,MAGED1,TPX2,CCNL2,CCNB1,UBE2I,S1PR2,DAZAP2,PRKACA,LYN,MAPK14,PARK7,PRNP,HNRNPA2B1,CDK5,CALM2,CRKL,RAP1A,SHC1,NVL,RALB,PIN1,KIF14,ADCY9,CDKN1B,CDC25B,F2R,ABI1,DVL2,MLST8,ADCY7,PLK1,COPS8,BAK1,CCT2,PSRC1,RFC3,MAP4K4,TAOK1,MRNIP,CDC6,TOPORS,UBE2V1,AURKB,DCUN1D5,RAB1A,RFC2,MAP3K4,PPP2CA,RPS27A,TAB2,AXIN1,GADD45B,RPLP1,CAB39,ADAM9,STK11,CLU,MAPK1,POT1,LRP8,MIF,HSPH1,RPS2,CLSPN,GORASP1,CHTF18,ZFP91,GADD45G,PRKAA1,VAV2,LAMTOR3,CIB1,DCUN1D4,PSEN1,PARN,FBXO5,CCNK,FGFR3,PDCD10,TIGAR,PTEN,PTPN11,ATG13,MDFIC,PTGES3,MAP3K14,GNAI2,PDPK1,TGFB1,TELO2,ADAM17,HMGN1,RHOA,MAPKAPK3,NEK7,JTB,PRKAR1B,KRAS,MAP4K3,ADRB2,MARK2,MAP2K2,MAPK3,XRCC5,NEK1,GOLGA2,CSK,OSBPL8,PKD2,MAP3K5,CD81,UBE2C,HRAS,ALS2 |
| 2.099e-02 | -3.86 | MALT_lymphoma | COSMIC cancer mutations | MALT_lymphoma | 20 | 7 | 17385 | 2587 |
KRAS,NOTCH2,DNMT3A,NRAS,TNFAIP3,HRAS,CDKN2A |
| 2.099e-02 | -3.86 | fibroma-thecoma-fibrothecoma | COSMIC cancer mutations | fibroma-thecoma-fibrothecoma | 20 | 7 | 17385 | 2587 |
GNAS,KRAS,STK11,BRCA1,NRAS,HRAS,CDKN2A |
| 2.099e-02 | -3.86 | ovary-sex_cord-stromal_tumour-fibroma-thecoma-fibrothecoma | COSMIC cancer mutations | ovary-sex_cord-stromal_tumour-fibroma-thecoma-fibrothecoma | 20 | 7 | 17385 | 2587 |
GNAS,KRAS,STK11,BRCA1,NRAS,HRAS,CDKN2A |
| 2.099e-02 | -3.86 | V$ARNT_01 | MSigDB lists | V$ARNT_01 | 244 | 49 | 17377 | 2626 |
ZBTB10,DNMT3A,ZFP91,SCYL1,UBXN1,RLF,STMN1,SYNRG,COMMD8,DNAJB9,CSDE1,FAM192A,TFAP4,ATP6V0B,SLC38A5,UTP18,ATG3,PRDM4,CRY2,MRPL40,ANKHD1,DVL2,CCAR1,NUDC,SNX8,AMPD2,B3GALT6,AATF,SNX2,C16orf72,SIGMAR1,ILF3,UBE4B,NDUFA7,PBRM1,ODC1,PICALM,EIF3A,RPA1,HMGN2,ADSS,SYNCRIP,BRD2,HPS5,ATP6V1C1,CLN3,ABCA1,RAB3IL1,RHEBL1 |
| 2.099e-02 | -3.86 | ACTC1 (actin, alpha, cardiac muscle 1) | protein interactions | 70 | 68 | 18 | 17029 | 2761 |
MIB2,PDCD6IP,DYNLL1,WIPF1,SMARCA4,EZR,PLEC,MCM2,TWF2,MPC1,WAS,EIF4A3,UCHL5,DAPK1,ACTB,ARRB2,CFL1,CAPN1 |
| 2.099e-02 | -3.86 | RBM42 (RNA binding motif protein 42) | protein interactions | 79171 | 68 | 18 | 17029 | 2761 |
SART1,MRPS2,RAB11B,MRPS26,PRPF3,MRPS14,PCBP1,APP,RBM4,SNRPA,RCC1L,SF3B2,CAND1,RPS14,PRPF4,SNRPG,SMNDC1,CAMK2G |
| 2.099e-02 | -3.86 | UBE2U (ubiquitin conjugating enzyme E2 U) | protein interactions | 148581 | 68 | 18 | 17029 | 2761 |
MIB2,RNF25,PCGF6,SYVN1,PCGF1,TRIM65,TRIM28,TRIM47,MDM2,GOLGA2,RNFT1,PML,TRIM32,RNF26,RNF14,RNF139,RNF5,RNF114 |
| 2.099e-02 | -3.86 | TUBB4A (tubulin beta 4A class IVa) | protein interactions | 10382 | 68 | 18 | 17029 | 2761 |
STAU1,CYLD,CUL3,CUL1,CDK13,IL12RB1,MCM2,METTL22,LYN,TUBGCP2,GLMP,FAS,MCM5,CAMKMT,STK11,ARRB2,CD81,TUBB |
| 2.099e-02 | -3.86 | RABGAP1L (RAB GTPase activating protein 1 like) | protein interactions | 9910 | 68 | 18 | 17029 | 2761 |
CCDC93,MAX,RPRD1A,GGA1,TRIM11,ACAP1,RCOR1,NUF2,PSMD9,GIT2,HMG20A,CYB5A,OIP5,RB1,GRIPAP1,ARNTL,CORO1A,SGF29 |
| 2.099e-02 | -3.86 | LYPD4 (LY6/PLAUR domain containing 4) | protein interactions | 147719 | 68 | 18 | 17029 | 2761 |
JMJD4,OAF,TOR3A,AP3M2,KRAS,EDEM2,BORA,ASPHD2,KIF18A,SEC23IP,POLE,NAGLU,CTR9,ECD,ESPL1,N4BP2L2,VPS13B,USP34 |
| 2.101e-02 | -3.86 | negative regulation of biological process | biological process | GO:0048519 | 5221 | 838 | 17256 | 2622 |
HECA,FGFR1OP,TSC2,ADD1,KDM4A,XIAP,PPP1R16B,MIEN1,RBM4,EEF2K,RPL23A,CDK5,CALM2,CDKN2C,USF1,PSMD1,CIPC,SRSF4,PDS5B,DNM2,CRY2,NUP153,FNIP2,RNF26,TIPARP,SENP1,PCBP2,MLST8,BAK1,PLK3,PGAP2,ERCC1,TMEM115,AATF,GABPA,EHMT1,MCL1,TOPORS,NUTF2,MCM2,ARF4,PLEKHF2,KRIT1,BRMS1,MID1IP1,SMAD2,RAD18,RPS27A,LIMK1,AXIN1,PRDX5,MYO18A,OGT,RNASEL,SMG9,TFDP2,SMAD1,E2F2,OAZ1,PDCD4,CLSPN,PHF23,TRIO,DHX9,RAB23,TOP2B,EIF2AK4,ZNRF3,PSMD9,PARN,CDC73,LMNA,DDRGK1,TFAP4,CD59,SMC3,INTS7,MEGF8,FBXO7,PHF14,MYDGF,MVP,PABPC1,CYFIP1,IFRD1,RBM42,ETV3,FOXK1,RB1CC1,ZMYND11,MTA2,ERO1A,GTPBP4,RPS10,ITM2A,USP10,BCLAF1,CBFA2T2,RHOB,ETS2,DUSP3,CSK,CNOT6,ZNF830,RUFY3,RNF139,EGLN1,ZNF207,ANKRD27,ZNF296,KARS,PPP1R37,GGNBP2,NQO1,IVNS1ABP,UBR2,PTTG1,ANK3,C5orf30,WDTC1,MYH9,PRKACA,STMN1,GLRX3,RCOR3,STAM,APP,ATP2A2,SP100,SH3BP1,MTA1,TBC1D14,NABP1,MAVS,CEP63,ATF2,RBM15,GPD1L,CGGBP1,PDCL3,RNF169,CPNE1,ULK3,PSRC1,EID1,GOPC,MAP4K4,RPL38,POLR2D,RNPS1,CIRBP,E2F3,HTATIP2,DNAJA1,DDX17,PPP2CA,CHCHD3,PEX5,LSM6,CORO1C,HIPK2,NT5C3B,RPLP1,TICAM1,PPP5C,LRP8,LRCH1,RPS2,TMBIM4,SRSF6,SESTD1,AKT1S1,ATP5F1B,IP6K2,ETS1,NEXMIF,SAPCD2,TUT4,RPA2,PSMD2,PDCD10,CLIC4,ITGB8,SUV39H2,PPP1R8,DCP1A,ANXA5,GTSE1,GTF2H2,TPCN1,SPTAN1,PDPK1,PPP3CA,TNFAIP3,EMP3,ZP3,PDE3B,PICALM,UTP20,SH3BP5,KEAP1,GPS2,WNT5B,PITX1,LRPPRC,PML,HMGB2,PSAP,PARP10,IGBP1,YWHAH,THAP5,FAF1,SNAPIN,THOC1,AAMDC,WDR13,TRIM11,PPP1R15B,FAM129A,RBM8A,ENSA,CSNK2A1,NENF,SND1,BIRC2,FANCI,CREM,PRNP,DLG5,PCNA,GLIS2,IL6ST,ZNF639,ETV6,PIK3R2,XRCC2,NOC2L,MYBL1,CCAR1,RYBP,PTPRK,PLK1,SP3,EXOSC6,PTPN18,RBX1,PBXIP1,BAZ2A,GMFB,EZR,CDC6,LRP5,PBRM1,EAF2,BRCA1,PRKRA,LUC7L,RHEB,OPTN,DPYSL3,TONSL,E2F4,SOCS4,ARRDC1,DVL1,CLN3,BEND6,SINHCAF,POT1,NUMB,ZNF564,ZCCHC9,PHB2,DNAJB2,CENPF,NKD2,LAMTOR3,CTCF,CDK13,DNAJB1,PPP3CB,CNOT11,CRLF3,LRRC14,RB1,MLX,CCP110,TIGAR,MBD2,ZNF746,ARL6IP1,CTR9,TIMELESS,MDFIC,LRSAM1,ABHD2,LDB1,CAMSAP1,KRAS,EIF2AK1,RTF1,EIF4G2,BBS12,ZNF174,PSMC4,RPL36,MBIP,PCM1,PALB2,SYNCRIP,ORMDL2,LAMTOR4,NLRC5,RUVBL2,ATP5F1A,BTBD10,USP7,CYLD,RPLP2,ARID2,FOXM1,NDUFAF2,DYNLL1,RRAGC,ZADH2,LYN,DUSP22,RPL11,CSDE1,ZBTB21,PSMA6,MDM2,TNFAIP8,PIN1,PPME1,TARDBP,CORO1A,LMAN1,STRAP,CTDSP2,DVL2,PRPF19,SNX25,PPIF,RPL29,TIMP2,RPL35,BIRC3,POLR2G,PPT1,PSMA8,RAB7A,BTG2,NFATC2,RHBDF2,RPSA,USP36,DNAJC10,ATP1A1,IDE,SCAP,RBL1,MAFK,PSMD3,STK38,DNAJC17,CHMP4B,H3F3A,CHID1,SMAD4,ZC3HC1,PARD3,BCL2L12,CTDP1,UNK,DAP,CDT1,AGO2,ARID5A,NKRF,ARF1,CSNK1A1,SCYL2,DNAJB9,FZD6,PTPN2,IRF4,RNF5,RNLS,RBM15B,RHOA,HMGN5,BTAF1,PRKDC,ZNF202,RANGAP1,API5,TRIM26,PDCD6,BIRC5,TWSG1,E2F1,GLG1,PKD2,RBPJ,NR2F2,HIPK3,IFI16,TXN,ZNF496,MAX,H2AFZ,ADAM10,TSC22D3,TMEM109,YTHDF3,CUL1,PLXNA1,CCNB1,UBE2I,COMMD6,PARK7,RIC1,ANKRD26,PA2G4,PARPBP,AP2B1,TRA2B,PLCL2,SMARCE1,DNMT1,CDC5L,SRSF10,KLF10,AKT2,PBK,NSUN2,MRNIP,DDX20,AURKB,CCNF,SLC25A5,EIF3A,DOT1L,HHEX,WAS,PSMD8,RPS14,MAP4,ITGB1,ARRB2,HDAC2,SVIP,DDX58,HSPH1,DNAJC5,MAPRE1,GMFG,HLA-E,PRKAA1,GSPT2,B4GALT1,NOTCH2,PSEN1,METTL3,VPS25,NPLOC4,CNOT3,JMY,CFLAR,RTKN,FKBP1A,EXOSC7,MEX3C,KLF16,HDAC7,DAD1,MSH2,DAPK1,FBXL7,PIK3IP1,RNF135,GNAI2,TNRC18,LPCAT1,TMED2,MORC3,TERF2,SOCS5,USF3,RPS24,EXOSC9,ARID1A,ADRB2,CAPZA2,FXR1,PTTG1IP,KDM3A,PATL1,MAP2K2,PSMB3,PHF6,FAS,XRCC5,CAT,PFDN5,EPRS,SERTAD2,GOLGA2,RBMX,QARS,ARAP1,CEBPG,PIAS2,CABIN1,YY1,CDK2,ZC3HAV1,CDKN2A,DNMT3A,RPS6KA1,RAF1,SUZ12,CAST,RAC1,MAGED1,BCL2L1,EPM2A,PAIP2,TERF2IP,SPINDOC,APLP2,SHC1,MTMR4,UCHL5,SOCS6,CDKN1B,TP53BP2,NAA35,CDK12,TMBIM1,CFL1,GPX4,SAP30,ANKLE2,CDKN2AIP,ERF,CDC123,DRAP1,TAOK1,CUL3,VDAC2,PKMYT1,H2AFV,PSMB9,ERC1,TRIM28,SOCS7,ZNF282,CHMP4A,PPP2R5A,DGCR8,H2AFX,STAT1,TRIM32,BEND3,EYA2,POLQ,POU3F2,OTUD5,NCOR2,DEPDC1,MECP2,TCF3,BABAM1,CBLL1,BRAP,SECISBP2,BLM,SPDL1,FOXO3,HMG20A,MAD2L2,WWP2,RFWD3,CCNK,RPL17,PTEN,CENPJ,PTPN11,AXIN2,RPL19,UPF2,CITED2,CNOT6L,CREB1,MSH6,NCOA2,TSHZ1,KAT2A,ILF3,RPL8,TBRG4,KCNQ1,OTUD3,RPL27A,FADD,CBX3,TMEM127,HGS,RPL32,PRDX3,ZHX1,TFDP1,OAZ2,KHSRP,PPP1R11,DDX5,TAF6,CPEB2,ESPL1,PURA,HIGD2A,DDB1,RORB,ZBED3,NPHP4,GPR132,PLXNC1,ST13,NF1,KMT2E,SIRT2,UBQLN2,MAPK14,BECN1,EDC3,RAP1A,CYREN,CDC42,EIF4A3,THADA,METTL14,ATG3,JAZF1,PPP1R12C,SRI,AKR1B1,SLC35C2,OGG1,CARMIL1,ARID4A,TRIM14,CARM1,SRPK2,COPS8,DEAF1,LARS,TRIM8,NCK1,VHL,RIOX2,RRM2,ARHGDIB,SOX4,ABHD5,RPL37,PAF1,CXXC4,EIF4ENIF1,PPM1G,CAB39,ZNF268,STK11,CHEK2,CLU,VPS4A,ROCK1,RPS26,PSMC1,UBE2D3,RPS15,PPP1R2,PPP1R12A,GORASP1,UBXN1,CIB1,EPN1,TIA1,RPL15,MEF2A,THRAP3,RGS2,TTF1,SRRT,RHBDD1,PRPF18,LYAR,DTL,NFATC3,BANF1,EI24,FAM89B,CAPZA1,KIFAP3,BCL2,YBX1,KNTC1,MCPH1,ZNF189,ATP5IF1,TRAFD1,CREG1,ERLIN1,CIC,OXR1,RPL6,GBA,PSMA1,SYVN1,DAPK3,ISG15,MASTL,TSC1,KLHL15,NFIL3,SIAH2,NUP62,YWHAZ,CTSA,ZFP90,RBBP4,SNRNP70,TMEM14A,TOB1,N4BP2L2,ADNP2,WASF2,MBD1,CHMP2A,PRKAB1,ASH1L,FEZ2,MPHOSPH8,CHERP,SMARCA4,IRF3,TWF2,MXD1,PAIP1,HNRNPA2B1,SAP130,RRN3,BABAM2,KIF14,EXOSC1,AKAP8,FAM3A,F2R,ABI1,HTRA2,RLIM,MOSPD1,CHP1,UBQLN4,FAM172A,ZNF500,PGGT1B,PCGF6,PSMB7,ATXN1,GLO1,ERBIN,MBD3,RPS9,TAB2,HNRNPR,TULP3,STAT6,GADD45B,ARNTL,GAS2,CCDC125,SMURF1,MAPK1,ABCA1,CBX4,MIF,DNAJC2,GCLM,TRIP12,EYA1,SRGN,CDK2AP2,KLF13,PAWR,MXD4,RGS1,FBXO5,FGFR3,GRK2,KLHL20,KMT5A,PELO,TANK,DUS2,NABP2,H2AFY,BRD7,ARHGEF2,STAT3,TGFB1,SAMD4B,PPP1R9B,ADAM17,ASPM,PSPC1,HELB,PRKAR1B,RFFL,RCOR1,WDR81,PRMT2,MEN1,NDRG3,MFN2,HSPA1B,CNOT9,LEMD2,UPF1,ATAD2,PLAA,OSBPL8,ZC3H7B,KMT2B,HRAS,TERF1 |
| 2.101e-02 | -3.86 | azurophil granule lumen | cellular component | GO:0035578 | 90 | 21 | 18223 | 2701 |
ADA2,FTL,CCT2,CREG1,ARHGAP45,HEXB,HEBP2,MAN2B1,NHLRC3,TOLLIP,CCT8,GNS,PA2G4,PSMD1,DSN1,ACLY,IMPDH1,CTSA,MAPK1,GM2A,TUBB |
| 2.104e-02 | -3.86 | GRB2 (growth factor receptor bound protein 2) | protein interactions | 2885 | 588 | 114 | 17029 | 2761 |
WASF2,PRKAB1,PDCD6IP,CYLD,REPS2,TSC2,ADAM10,RPS6KA1,RAC1,HEXB,MYH9,POMP,FKBP2,MAPK14,REPS1,APP,PRNP,PHC2,CRKL,HNRNPA2B1,ABL2,VAV1,BABAM2,ASAP2,SHC1,SYNM,CDC42,WDR44,ABRAXAS2,IL6ST,MTA1,PIK3R2,ETV6,DNM2,AP2B1,CDKN1B,TP53BP2,TFG,DCTN1,CCT2,ARHGAP17,SNRNP200,PTPN18,PBXIP1,NCK1,CUL3,SMU1,WIPF1,MCM2,SLC25A5,SOCS7,DDX17,AFDN,PON2,AHNAK,WAS,JAK1,RPS27A,MYO18A,SOCS4,MIA2,KPNA2,ACTB,FUS,CLU,FAU,PPP5C,E2F2,MAPK1,USP53,AP2S1,MYL12B,TUBB,OTUD5,LIME1,VAV2,CUTA,DCTN2,BABAM1,NKD2,ACAP1,RACGAP1,NCKAP1,CD59,GSTK1,RB1,FGFR3,VASP,SNX18,PTPN11,EEF1D,PPP3CA,FTL,CSRP1,PRRC2A,WDR1,KRAS,MAP4K3,ADRB2,PLEC,ELK1,CYFIP2,CCT8,IRF5,POLR2A,HSPA1B,HGS,SYNCRIP,CSK,ARAP1,YWHAZ,YWHAH,HRAS,HIPK3 |
| 2.106e-02 | -3.86 | Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha | REACTOME pathways | R-HSA-1234176 | 67 | 18 | 10287 | 1696 |
UBE2D3,PSMD2,PSMD1,PSMA6,PSMA8,RBX1,RPS27A,PSMD8,VHL,PSMD3,PSMB7,PSMA1,PSMB9,PSMD9,PSMC1,PSMB3,PSMC4,EGLN1 |
| 2.108e-02 | -3.86 | 7-methylguanosine mRNA capping | biological process | GO:0006370 | 33 | 10 | 17256 | 2622 |
POLR2I,POLR2J,POLR2G,POLR2L,POLR2K,CMTR2,POLR2D,GTF2H2,POLR2A,GTF2F1 |
| 2.108e-02 | -3.86 | protein targeting to vacuole | biological process | GO:0006623 | 33 | 10 | 17256 | 2622 |
NAGPA,GCC2,SCARB2,LARS,CLU,HGS,VPS4A,SMURF1,RAB7A,VTI1A |
| 2.108e-02 | -3.86 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | biological process | GO:0043928 | 33 | 10 | 17256 | 2622 |
EXOSC6,EXOSC7,LSM6,NT5C3B,EXOSC1,DCP1A,CNOT6,EXOSC9,PATL1,EDC3 |
| 2.112e-02 | -3.86 | QI_PLASMACYTOMA_DN | MSigDB lists | QI_PLASMACYTOMA_DN | 99 | 23 | 17377 | 2626 |
CYTIP,LZTR1,MAGEH1,KAT2A,MAGED1,NOL8,RNF25,GNE,TBRG4,ARFIP2,SND1,DUSP22,ITGB5,PARK7,PSMB3,USF1,PPP2R5A,DDOST,SEC61A1,STT3A,UCHL5,PRMT7,IPO4 |
| 2.112e-02 | -3.86 | chr20q11 | MSigDB lists | chr20q11 | 99 | 23 | 17377 | 2626 |
CPNE1,KIF3B,MAPRE1,TM9SF4,DLGAP4,TPX2,PLAGL2,BCL2L1,CBFA2T2,EDEM2,NDRG3,PPP1R16B,POFUT1,CTNNBL1,PDRG1,RBL1,ZNF335,E2F1,FAM83D,CHMP4B,AHCY,SLC35C2,RPRD1B |
| 2.114e-02 | -3.86 | GO_INTERACTION_WITH_HOST | MSigDB lists | GO_INTERACTION_WITH_HOST | 126 | 28 | 17377 | 2626 |
TGFB1,SELPLG,TAP1,BCL2L1,EIF2AK4,ITGB5,TFRC,RPSA,XPR1,HSPA1B,WWP2,CCNK,DERL1,SCARB2,KPNA4,KPNA1,IDE,ZNF639,SIVA1,HIPK2,ITGB1,NUP153,TAP2,KPNA2,SCARB1,CPSF4,CD81,ZC3HAV1 |
| 2.114e-02 | -3.86 | RODWELL_AGING_KIDNEY_DN | MSigDB lists | RODWELL_AGING_KIDNEY_DN | 126 | 28 | 17377 | 2626 |
CCDC93,NDUFS1,RHOBTB3,MUT,NF1,GNG7,SLC16A7,CSNK2A1,CYCS,OAT,FXR1,PDE3B,MTR,SLC25A36,GNAS,FBXO3,FBXO21,APLP2,UAP1,GOT2,UCHL5,CYB5RL,HADHB,SIAH2,LRPPRC,SLC22A23,NAA35,LDHB |
| 2.114e-02 | -3.86 | GSE7459_UNTREATED_VS_IL6_TREATED_ACT_CD4_TCELL_UP | MSigDB lists | GSE7459_UNTREATED_VS_IL6_TREATED_ACT_CD4_TCELL_UP | 126 | 28 | 17377 | 2626 |
ORAI2,GALC,GABPA,NF1,TOR3A,YTHDC2,EHMT1,AGFG1,CBFA2T2,ASB13,NDRG3,SLC20A1,ZADH2,CRLF3,SNAPC4,DDX23,VAV1,SPATA2,GRIPAP1,DHX16,MAPK6,UPRT,BRD7,ATP6V0A2,DDX5,PIK3IP1,STAT3,DDX52 |
| 2.114e-02 | -3.86 | GSE13173_UNTREATED_VS_IL12_TREATED_ACT_CD8_TCELL_DN | MSigDB lists | GSE13173_UNTREATED_VS_IL12_TREATED_ACT_CD8_TCELL_DN | 126 | 28 | 17377 | 2626 |
POLK,PPP1R15B,SESTD1,DHX29,RAF1,DNAJB2,RNF25,GSPT2,CENPF,PCGF6,LAGE3,EIF2AK4,CBFA2T2,MIS12,EEF2K,TERF2IP,ADSS,PPP1R3B,MDM2,UBE2Q2,GOLGA7,NSMCE2,TNPO3,BCAP29,CPEB2,TMBIM1,MRPL32,TMX1 |
| 2.115e-02 | -3.86 | Transcriptional regulation by small RNAs | REACTOME pathways | R-HSA-5578749 | 106 | 26 | 10287 | 1696 |
NDC1,POLR2I,H2AFZ,NUP188,POLR2G,POLR2L,POLR2K,RAE1,AGO2,NUP54,POLR2D,NUP155,H2AFV,NUP205,POLR2A,NUP210,POLR2J,NUP107,H2AFX,NUP62,NUP153,H3F3A,NUP85,NUP58,AAAS,SEH1L |
| 2.115e-02 | -3.86 | core promoter sequence-specific DNA binding | molecular function | GO:0001046 | 87 | 21 | 17224 | 2647 |
POU2AF1,ZFP64,H2AFZ,KLF10,BAZ2A,WBP2,SMARCA4,THRAP3,SOX4,KDM3A,UBTF,RRN3,NRF1,MTA1,ARNTL,STAT1,ZNF335,NLRC5,H2AFY,RUVBL2,H3F3A |
| 2.116e-02 | -3.86 | Proteasome | KEGG pathways | ko03050 | 45 | 13 | 7161 | 1149 |
PSMD2,PSMA6,PSMD1,PSMA8,PSMD3,PSMD8,PSMB7,PSMA1,POMP,PSMB9,PSMC1,PSMB3,PSMC4 |
| 2.116e-02 | -3.86 | Proteasome | KEGG pathways | hsa03050 | 45 | 13 | 7161 | 1149 |
PSMD2,PSMA6,PSMD1,PSMA8,PSMD3,PSMD8,PSMB7,PSMA1,POMP,PSMB9,PSMC1,PSMB3,PSMC4 |
| 2.117e-02 | -3.86 | nuclease activity | molecular function | GO:0004518 | 212 | 44 | 17224 | 2647 |
AGO2,PMS2,TATDN3,LACTB2,SND1,PARN,EDC3,MBD4,ANKLE1,EXOSC7,PPP1R8,RNASEK,POP7,PELO,EXOSC1,XRCC2,RNASEH2A,ERI3,CPSF4,CNOT6L,N4BP2,OGG1,ZC3H3,RPP25,TDP1,ERCC1,EXOSC6,TRIR,EXOSC9,DCLRE1C,RAD51C,POLE,DGCR8,TATDN2,LRPPRC,AEN,CNOT6,XRCC3,RNASEL,TATDN1,GEN1,TSEN15,RAD51D,POLQ |
| 2.117e-02 | -3.86 | PInositol-4-P-5-kinase_N | interpro domains | IPR027484 | 8 | 4 | 18492 | 2768 |
PIKFYVE,PIP4K2A,PIP5K1C,PIP4K2C |
| 2.117e-02 | -3.86 | Clathrin_sm-chain_CS | interpro domains | IPR000804 | 8 | 4 | 18492 | 2768 |
AP1S1,AP3S1,AP2S1,AP3S2 |
| 2.117e-02 | -3.86 | FCP1_dom | interpro domains | IPR004274 | 8 | 4 | 18492 | 2768 |
CTDP1,CTDSP2,TIMM50,UBLCP1 |
| 2.117e-02 | -3.86 | Bcl2_BH3_motif_CS | interpro domains | IPR020728 | 8 | 4 | 18492 | 2768 |
BAK1,BCL2,MCL1,BCL2L1 |
| 2.117e-02 | -3.86 | Bcl2_BH1_motif_CS | interpro domains | IPR020717 | 8 | 4 | 18492 | 2768 |
BAK1,BCL2,MCL1,BCL2L1 |
| 2.117e-02 | -3.86 | BIR_rpt | interpro domains | IPR001370 | 8 | 4 | 18492 | 2768 |
BIRC3,BIRC5,BIRC2,XIAP |
| 2.117e-02 | -3.86 | Bcl2_BH2_motif_CS | interpro domains | IPR020726 | 8 | 4 | 18492 | 2768 |
BAK1,BCL2,MCL1,BCL2L1 |
| 2.117e-02 | -3.86 | CID_dom | interpro domains | IPR006569 | 8 | 4 | 18492 | 2768 |
RPRD1A,CHERP,RPRD1B,U2SURP |
| 2.117e-02 | -3.86 | E2F | interpro domains | IPR015633 | 8 | 4 | 18492 | 2768 |
E2F2,E2F4,E2F1,E2F3 |
| 2.117e-02 | -3.86 | PInositol-4-P-5-kinase_core | interpro domains | IPR002498 | 8 | 4 | 18492 | 2768 |
PIKFYVE,PIP4K2A,PIP5K1C,PIP4K2C |
| 2.118e-02 | -3.85 | SMURF2 (SMAD specific E3 ubiquitin protein ligase 2) | protein interactions | 64750 | 128 | 30 | 17029 | 2761 |
UBE2D3,RAB14,SMAP1,RHOA,NRAS,CCM2,IRF3,DAZAP2,UBE2I,SLC25A5,SF3A2,RAB22A,DNAJC10,SMAD2,NEK6,ABRAXAS2,RPS27A,AXIN1,SRSF4,SOCS6,TNPO3,YBX1,MAVS,YY1,SNRNP70,SMAD1,SMURF1,SMAD4,FUBP1,RLIM |
| 2.120e-02 | -3.85 | skin-malignant_melanoma-nodular | COSMIC cancer mutations | skin-malignant_melanoma-nodular | 29 | 9 | 17385 | 2587 |
FGFR3,NRAS,PTEN,SF3B1,RAC1,KRAS,MEN1,HRAS,CDKN2A |
| 2.123e-02 | -3.85 | GSE6674_UNSTIM_VS_PL2_3_STIM_BCELL_UP | MSigDB lists | GSE6674_UNSTIM_VS_PL2_3_STIM_BCELL_UP | 137 | 30 | 17377 | 2626 |
TMEM106C,RORB,TDP1,LYRM4,KLHL21,SELPLG,TCF3,WDHD1,DNAJC9,NIT2,TOMM40,FOXO3,BZW2,APLP2,GART,GOT2,RNF38,PRC1,COX8A,ACAT1,SUCLG2,PCYT2,ACADM,CHEK2,RNASEH2A,POLR1B,COPS6,MYO9A,NGLY1,WDR41 |
| 2.125e-02 | -3.85 | - | gene3d domains | 1.10.10.10 | 233 | 49 | 8148 | 1295 |
RECQL,PARP12,DEPDC1,ARID2,FOXM1,SHPRH,CUL1,IRF3,LACTB2,BLM,ETS1,FOXO3,VPS25,GTF2F1,DDRGK1,RPA2,PA2G4,IRF4,ETV6,FOXN2,PIKFYVE,DVL2,HP1BP3,ETV3,FOXK1,ERF,GABPA,KAT7,CUL3,RPS10,E2F3,TIGD5,ANAPC2,CDC6,PLEC,ELK1,KDM1B,IRF5,EIF3K,ETS2,E2F4,TFDP1,E2F1,CENPBD1,DVL1,TFDP2,E2F2,ZC3HAV1,TIGD2 |
| 2.126e-02 | -3.85 | Trans-sulfuration and one carbon metabolism | WikiPathways | WP2525 | 32 | 10 | 5312 | 837 |
MAT2B,GCLM,DNMT3A,MTHFD2,AHCY,DHFR2,AHCYL1,DNMT1,MTR,MAT2A |
| 2.128e-02 | -3.85 | maturation of LSU-rRNA | biological process | GO:0000470 | 24 | 8 | 17256 | 2622 |
NSA2,RPL35,NOP2,RRP15,GTPBP4,RPF2,MAK16,FTSJ3 |
| 2.128e-02 | -3.85 | response to misfolded protein | biological process | GO:0051788 | 24 | 8 | 17256 | 2622 |
DERL1,ANKZF1,SDF2L1,CLU,ATXN3,KLHL15,RNF5,CUL3 |
| 2.128e-02 | -3.85 | nucleotide-excision repair, DNA gap filling | biological process | GO:0006297 | 24 | 8 | 17256 | 2622 |
RPA2,RFC3,PCNA,POLE,POLK,RPS27A,RFC2,RPA1 |
| 2.128e-02 | -3.85 | establishment of mitotic spindle localization | biological process | GO:0040001 | 24 | 8 | 17256 | 2622 |
ARHGEF2,NUSAP1,NDE1,SPDL1,MCPH1,ESPL1,SAPCD2,DCTN1 |
| 2.128e-02 | -3.85 | viral budding | biological process | GO:0046755 | 24 | 8 | 17256 | 2622 |
CHMP2A,CHMP4A,PDCD6IP,CHMP4B,VPS4A,CHMP2B,CHMP7,LRSAM1 |
| 2.130e-02 | -3.85 | RSRC1 (arginine and serine rich coiled-coil 1) | protein interactions | 51319 | 40 | 12 | 17029 | 2761 |
EXOSC7,CSNK2A1,RACGAP1,EXOSC9,JMJD6,PPP3CB,SNRPG,CFAP20,DVL2,DDX23,SRPK2,PAPOLA |
| 2.130e-02 | -3.85 | ZCCHC17 (zinc finger CCHC-type containing 17) | protein interactions | 51538 | 40 | 12 | 17029 | 2761 |
FTL,LAP3,ZNF512,MECP2,PTTG1,RNPS1,CSNK2A1,JMJD6,APP,RBM4,SAP30,SRPK2 |
| 2.130e-02 | -3.85 | ALDH7A1 (aldehyde dehydrogenase 7 family member A1) | protein interactions | 501 | 40 | 12 | 17029 | 2761 |
CAT,KIF2A,CAPN2,DDA1,PRDX5,UBA5,KBTBD7,EIF5,YWHAH,XRCC4,APP,LDHB |
| 2.130e-02 | -3.85 | FAAP100 (Fanconi anemia core complex associated protein 100) | protein interactions | 80233 | 40 | 12 | 17029 | 2761 |
FANCL,GGA1,SNAP29,RMI2,TOP3A,PACS1,BLM,FANCE,RMI1,RPL22L1,APP,SGF29 |
| 2.130e-02 | -3.85 | POR (cytochrome p450 oxidoreductase) | protein interactions | 5447 | 40 | 12 | 17029 | 2761 |
DERL1,SNX8,NDUFV1,EWSR1,STAT1,PGRMC1,TMEM216,NDUFB9,SYVN1,PLOD3,CYB5A,EVC2 |
| 2.130e-02 | -3.85 | MPHOSPH6 (M-phase phosphoprotein 6) | protein interactions | 10200 | 40 | 12 | 17029 | 2761 |
FTL,EXOSC6,EXOSC7,AATF,ZHX1,EXOSC1,DNM2,SMARCA4,EXOSC9,PRPF3,PARN,EIF3G |
| 2.130e-02 | -3.85 | Ptpn23 (protein tyrosine phosphatase, non-receptor type 23) | protein interactions | 104831 | 40 | 12 | 17029 | 2761 |
CHMP2A,PDCD6IP,CHMP4A,CAPN7,FLOT1,ATP6V0A1,CHMP4B,ATP6V1B2,CHMP2B,ATP6V0D1,XPR1,STOML2 |
| 2.130e-02 | -3.85 | LIMK2 (LIM domain kinase 2) | protein interactions | 3985 | 40 | 12 | 17029 | 2761 |
ATP1A1,LIMK1,SLC25A22,FKBP5,DNAJA1,RUVBL2,ROCK1,HIPK3,PARD3,LMNA,CFL1,SLC25A1 |
| 2.130e-02 | -3.85 | PRKD2 (protein kinase D2) | protein interactions | 25865 | 40 | 12 | 17029 | 2761 |
DST,PRKD3,SEC23IP,GORASP1,ARPC5,HDAC7,RAE1,RRBP1,RFFL,TGOLN2,SNRNP70,GLRX3 |
| 2.130e-02 | -3.85 | PAAF1 (proteasomal ATPase associated factor 1) | protein interactions | 80227 | 40 | 12 | 17029 | 2761 |
PSMD2,VASP,TK1,PSMD1,CCDC6,UCHL5,PSMD8,PSMD3,PSMA1,PSMC1,UBLCP1,PSMC4 |
| 2.130e-02 | -3.85 | SPC24 (SPC24, NDC80 kinetochore complex component) | protein interactions | 147841 | 40 | 12 | 17029 | 2761 |
SKA3,NUP188,PCM1,DSN1,ASPM,NUF2,PMF1,TALDO1,SGF29,APP,MIS12,DCTN1 |
| 2.130e-02 | -3.85 | Ccdc9 (coiled-coil domain containing 9) | protein interactions | 243846 | 40 | 12 | 17029 | 2761 |
FYTTD1,NAP1L1,EIF4A3,PPIG,ILF3,RPL8,NAP1L4,ATP6V1B2,ATP6V0D1,HNRNPM,CSNK1D,DDX17 |
| 2.130e-02 | -3.85 | Acetyltransf_1 | pfam domains | PF00583 | 20 | 7 | 17054 | 2545 |
NAT14,GNPNAT1,NAA20,KAT2A,SAT2,NAA60,NAA50 |
| 2.131e-02 | -3.85 | V$SMAD4_Q6 | MSigDB lists | V$SMAD4_Q6 | 227 | 46 | 17377 | 2626 |
WASF2,ZNF296,WDR13,FAM129A,SRSF6,MRI1,TMEM109,DLGAP4,PPP3CB,GNB2,MYL6B,FBRS,TMEM69,ATP2A2,SUV39H2,ZNRF2,SSBP3,CREB1,ZNF710,SCYL3,ZNF800,DCTN1,POU2AF1,ELOVL5,PPP3CA,POLR2I,TRIM8,HMGN5,APH1A,LDB1,UBE4B,SYVN1,CADM1,PLEC,WDR81,ARID1A,VEZF1,ZNF282,HHEX,FASTK,FAM126A,PIEZO1,RTN3,ABCA1,PURA,ATXN7L2 |
| 2.132e-02 | -3.85 | PUA | prosite domains | PS50890 | 5 | 3 | 12060 | 1670 |
NIP7,EIF2D,MCTS1 |
| 2.132e-02 | -3.85 | ATPASE_ALPHA_BETA | prosite domains | PS00152 | 5 | 3 | 12060 | 1670 |
ATP5F1A,ATP5F1B,ATP6V1B2 |
| 2.132e-02 | -3.85 | NAC_AB | prosite domains | PS51151 | 5 | 3 | 12060 | 1670 |
BTF3,NACA,BTF3L4 |
| 2.132e-02 | -3.85 | DZF | prosite domains | PS51703 | 5 | 3 | 12060 | 1670 |
STRBP,ZFR,ILF3 |
| 2.132e-02 | -3.85 | YTH | prosite domains | PS50882 | 5 | 3 | 12060 | 1670 |
YTHDF3,YTHDC1,YTHDC2 |
| 2.134e-02 | -3.85 | GO_INSULIN_RECEPTOR_SIGNALING_PATHWAY | MSigDB lists | GO_INSULIN_RECEPTOR_SIGNALING_PATHWAY | 78 | 19 | 17377 | 2626 |
AKT2,ATP6V0A1,ATP6V1B2,AP3S1,APPL1,SOCS7,PTPN2,ATP6V0B,PDK2,IDE,ATP6V1D,SHC1,PIK3R2,ATP6V0A2,ATP6V0C,ATP6V1C1,ATP6V0D1,ATP6V0E1,ATP6V1G1 |
| 2.135e-02 | -3.85 | HMG_box_dom_sf | interpro domains | IPR036910 | 53 | 14 | 18492 | 2768 |
UBTF,SP100,CHD3,CIC,HMGXB3,BBX,WDHD1,HMGB2,PBRM1,KMT2C,SOX4,SMARCE1,HMG20A,SSRP1 |
| 2.138e-02 | -3.85 | GSE9960_HEALTHY_VS_GRAM_POS_SEPSIS_PBMC_DN | MSigDB lists | GSE9960_HEALTHY_VS_GRAM_POS_SEPSIS_PBMC_DN | 176 | 37 | 17377 | 2626 |
CYTIP,CDS2,TXN,PTTG1,UBE2Z,CUL1,IP6K2,DUSP22,TTF1,FANCL,UBXN2A,NSRP1,RAB35,DPYSL2,MBD2,TRIM14,METTL1,ACSL5,IFRD1,TRAFD1,ETV3,TNFAIP3,BIRC3,NET1,FOPNL,GTPBP4,NFATC2IP,PRPF3,ISG15,TMEM41A,BRD2,NFIL3,NLRC5,STAT1,NDE1,RUFY3,LRP8 |
| 2.138e-02 | -3.85 | GSE29618_PRE_VS_DAY7_FLU_VACCINE_MDC_DN | MSigDB lists | GSE29618_PRE_VS_DAY7_FLU_VACCINE_MDC_DN | 176 | 37 | 17377 | 2626 |
NAT9,PRPF38B,CKLF,EIF3D,ADO,CREBL2,TGOLN2,NOTCH2,PLXNA1,FAM136A,HCFC1R1,ASXL2,SS18L1,ATG13,CITED2,DVL2,ALDH9A1,SAP30,IFRD1,AMD1,LDHA,TBRG4,KCNQ1,MACF1,KLF6,EIF4G2,SYMPK,SPPL2B,FKBP3,ECH1,EIF3H,TSC1,PDCD6,FNTA,GLG1,PKD2,RUVBL2 |
| 2.138e-02 | -3.85 | GSE23114_PERITONEAL_CAVITY_B1A_BCELL_VS_SPLEEN_BCELL_IN_SLE2C1_MOUSE_DN | MSigDB lists | GSE23114_PERITONEAL_CAVITY_B1A_BCELL_VS_SPLEEN_BCELL_IN_SLE2C1_MOUSE_DN | 176 | 37 | 17377 | 2626 |
NDUFS1,TXN,ARID5A,VTI1A,EBNA1BP2,XPNPEP3,BCL2L1,SLC35B2,EIF1B,CD320,EPM2A,RPL11,TET3,NUDT19,CCDC50,DUT,DCP1A,AHCY,TAGLN2,PIKFYVE,SGCB,FAM171A1,NTPCR,TSPYL4,PLEC,SERP1,IRF5,GADD45B,CEBPG,SLC16A1,KHSRP,NUP62,MAP3K5,RPS6KC1,SLC25A33,GPATCH4,DDX52 |
| 2.145e-02 | -3.84 | TFG (TRK-fused gene) | protein interactions | 10342 | 123 | 29 | 17029 | 2761 |
CHMP2A,UNK,PDCD6IP,EWSR1,MAGED1,BABAM1,CUL3,HNRNPF,ATP6V0A1,CUL1,AURKB,BRCA1,MCM2,ATP6V1B2,PEF1,CAND1,SEC31A,CHMP4A,BABAM2,FBXL6,DGCR8,PIN1,CEP55,CHMP4B,COPS6,TOP1MT,TFG,IFI16,ANXA11 |
| 2.145e-02 | -3.84 | DNAJC7 (DnaJ heat shock protein family (Hsp40) member C7) | protein interactions | 7266 | 123 | 29 | 17029 | 2761 |
NPHP4,PTPN18,KIAA0100,NF1,PRKDC,CUL3,UBE4B,DNAJB1,MCM2,EVC2,GNAS,MKNK1,SMAD2,HSPA4,GART,POLE,NAA50,CRY2,TRIM32,FUS,PTGES3,LMAN1,WDR62,SMURF1,ESPL1,RNF5,VPS13B,WDR41,CDC37 |
| 2.148e-02 | -3.84 | SRSF12 (serine and arginine rich splicing factor 12) | protein interactions | 135295 | 73 | 19 | 17029 | 2761 |
NOL12,NF1,FAM53C,DENND4C,GSPT2,RAB3IP,USP21,GIGYF1,EDC3,RTKN,AFDN,ZBTB21,FAM110A,CLK3,KIF13B,CDC25B,SNRNP70,LUC7L2,SRPK2 |
| 2.148e-02 | -3.84 | ELP1 (elongator complex protein 1) | protein interactions | 8518 | 73 | 19 | 17029 | 2761 |
FOCAD,MRPL42,PRKDC,CUL3,ELP4,KRAS,PKM,MPG,PRDX1,PSMC4,MAN2A2,IRF4,SHC1,ELP5,NDUFB9,MAP3K14,PPP6R1,SNAPIN,CDC5L |
| 2.148e-02 | -3.84 | PHLDB2 (pleckstrin homology like domain family B member 2) | protein interactions | 90102 | 73 | 19 | 17029 | 2761 |
USP7,NF1,FAM53C,DENND4C,TWNK,DYNLL1,KIF23,RACGAP1,RAB3IP,CAPZA2,USP21,GIGYF1,RTKN,ZBTB21,FAM110A,KIF13B,MYO18A,CDC25B,DVL2 |
| 2.148e-02 | -3.84 | KLC2 (kinesin light chain 2) | protein interactions | 64837 | 73 | 19 | 17029 | 2761 |
EXOC3,TIMM8B,FGFR1OP,MRPS2,EID1,KLC1,SMC6,LYN,PATL1,APP,MIS12,KIF5B,KIF2A,CENPJ,PPIL2,ARHGEF2,YWHAZ,COIL,GEMIN7 |
| 2.154e-02 | -3.84 | GSE15930_STIM_VS_STIM_AND_IFNAB_48H_CD8_T_CELL_DN | MSigDB lists | GSE15930_STIM_VS_STIM_AND_IFNAB_48H_CD8_T_CELL_DN | 193 | 40 | 17377 | 2626 |
SRM,DNAJC5,GPR132,SYS1,NOP2,AGRN,TAP1,TMEM165,PSMD1,CLIC4,RABGAP1L,PPA1,TRAFD1,ATP13A1,DDX24,CREG1,PGS1,LRBA,TOR1AIP2,UHRF1BP1,IL12RB1,OGFR,ISG15,IRF5,RHOB,PI4K2A,GEMIN5,HLA-B,MTHFD2,BRD2,STAT1,E2F1,PML,BAZ1B,PREPL,CLN3,UBE2C,ABCA1,BYSL,FAF1 |
| 2.156e-02 | -3.84 | intrinsic component of mitochondrial membrane | cellular component | GO:0098573 | 69 | 17 | 18223 | 2701 |
BAK1,COA3,TOMM20,IMMT,ABCB10,RHOT1,SLC25A44,TOMM40,RHOT2,CHCHD6,MPC1,MFN2,CHCHD3,TIMM23,TIMM17A,SLC25A19,APOOL |
| 2.160e-02 | -3.84 | protein acetylation | biological process | GO:0006473 | 131 | 29 | 17256 | 2622 |
KAT2A,KAT7,MECP2,MDH2,LDB1,ELP4,TAF6L,USP22,WDR5,SUPT7L,MBD3,MEAF6,IRF4,MBIP,BRPF3,TEX30,OGT,NAA50,KANSL2,TAF5L,RUVBL2,BEND3,NCOA1,TAF12,NAA20,ATF2,NAA35,NAA60,SGF29 |
| 2.162e-02 | -3.83 | BILANGES_RAPAMYCIN_SENSITIVE_GENES | MSigDB lists | BILANGES_RAPAMYCIN_SENSITIVE_GENES | 38 | 11 | 17377 | 2626 |
RPS15,RPL35,BRAP,SREK1,POLR1B,PPWD1,SMC2,SLC12A9,NEU1,RPL11,RPL23A |
| 2.162e-02 | -3.83 | GO_SOMATIC_DIVERSIFICATION_OF_IMMUNE_RECEPTORS | MSigDB lists | GO_SOMATIC_DIVERSIFICATION_OF_IMMUNE_RECEPTORS | 38 | 11 | 17377 | 2626 |
ERCC1,EXOSC6,CTNNBL1,PRKDC,TCF3,PMS2,MSH2,HMGB2,DCLRE1C,MSH6,POLQ |
| 2.162e-02 | -3.83 | MODULE_447 | MSigDB lists | MODULE_447 | 38 | 11 | 17377 | 2626 |
CCT2,RPL29,SEC61B,GPS2,EIF3D,ANXA5,BMS1,RBPJ,SNRPA,EIF3H,FAF1 |
| 2.162e-02 | -3.83 | GO_AMINO_SUGAR_METABOLIC_PROCESS | MSigDB lists | GO_AMINO_SUGAR_METABOLIC_PROCESS | 38 | 11 | 17377 | 2626 |
CMAS,GNPNAT1,UAP1,GNPDA1,GNE,CTBS,OGT,ST3GAL2,AMDHD2,NANP,CHID1 |
| 2.164e-02 | -3.83 | UIM_dom | interpro domains | IPR003903 | 20 | 7 | 18492 | 2768 |
EPN1,HGS,ANKRD13D,ATXN3,DNAJB2,ANKIB1,STAM |
| 2.167e-02 | -3.83 | CTACCTC,LET-7A,LET-7B,LET-7C,LET-7D,LET-7E,LET-7F,MIR-98,LET-7G,LET-7I | MSigDB lists | CTACCTC,LET-7A,LET-7B,LET-7C,LET-7D,LET-7E,LET-7F,MIR-98,LET-7G,LET-7I | 367 | 70 | 17377 | 2626 |
TRIM41,DCAF15,PPP1R15B,ABCC10,PLAGL2,NHLRC3,BCL2L1,SNN,SLC20A1,PPP1R16B,MXD1,ANKRD28,AHCTF1,ATP2A2,RALB,CRY2,ZC3H3,ZNF583,ABCC5,NRAS,MAP4K4,MEF2D,CCNF,DHX57,GPR137,DOT1L,ZNF282,BRWD1,SPATA2,NSMCE2,SOCS4,UHRF2,AP1S1,NCOA1,SPRYD4,COIL,NXT2,INTS2,PRPF38B,MECP2,KCTD17,DLGAP4,BZW2,MED8,RNFT1,LTN1,ZNF710,CPSF4,STAT3,RNF5,SIGMAR1,RDH10,KIAA0930,MAP4K3,ADRB2,EIF4G2,RBM38,SMAP2,MYO1F,TSC1,PLD3,NAP1L1,GOLGA7,TTLL4,QARS,MAPK6,USP32,RUFY3,CPEB2,NIPA1 |
| 2.168e-02 | -3.83 | p53 signaling pathway | KEGG pathways | hsa04115 | 69 | 18 | 7161 | 1149 |
TSC2,GADD45G,RRM2,GORAB,CYCS,CCNB1,FAS,MDM2,SIAH1,PTEN,GADD45B,EI24,GTSE1,CHEK2,CDK2,CCNB2,ZMAT3,CDKN2A |
| 2.168e-02 | -3.83 | p53 signaling pathway | KEGG pathways | ko04115 | 69 | 18 | 7161 | 1149 |
TSC2,GADD45G,RRM2,GORAB,CYCS,CCNB1,FAS,MDM2,SIAH1,PTEN,GADD45B,EI24,GTSE1,CHEK2,CDK2,CCNB2,ZMAT3,CDKN2A |
| 2.172e-02 | -3.83 | V$CREB_02 | MSigDB lists | V$CREB_02 | 233 | 47 | 17377 | 2626 |
UBE2D3,CYLD,ST13,HNRNPAB,MUT,THOC1,NF1,IVNS1ABP,YTHDC2,AGPAT1,YTHDF3,CBLL1,CNTROB,XPNPEP3,USP48,XPR1,ABHD16A,CDC42,THADA,DAD1,SSBP3,ZFYVE27,TAGLN2,FBXL19,RNF5,KDELR1,DCTN1,EIF5A,PHF20L1,DDX28,ELL2,TMEM39A,ERF,SCFD2,ANAPC2,ZFAND5,ERC1,USP36,SRSF1,BRMS1,SDHB,HPS5,YWHAZ,SSNA1,SNRPG,ALS2,SMARCD1 |
| 2.175e-02 | -3.83 | GSE26488_WT_VS_HDAC7_KO_DOUBLE_POSITIVE_THYMOCYTE_UP | MSigDB lists | GSE26488_WT_VS_HDAC7_KO_DOUBLE_POSITIVE_THYMOCYTE_UP | 165 | 35 | 17377 | 2626 |
SLC30A9,HECA,GOLIM4,GXYLT1,UBN1,SESTD1,YTHDC2,HMG20A,YY1AP1,C2orf68,SLC25A36,TERF2IP,CSDE1,DTL,RPN1,EXOSC7,PIGG,UPF2,TECR,FRMD8,ALDH9A1,SRSF10,BCLAF1,STX16,MATR3,DHX15,RXRB,CCDC127,ADSS,ZHX1,OSBPL8,CDCA7L,ANP32E,IDH3B,TOB1 |
| 2.178e-02 | -3.83 | Loss of Nlp from mitotic centrosomes | REACTOME pathways | R-HSA-380259 | 72 | 19 | 10287 | 1696 |
PLK1,FGFR1OP,MAPRE1,DYNLL1,DCTN2,HAUS4,PRKACA,HAUS2,HAUS8,PCM1,CCP110,CENPJ,ODF2,SSNA1,CEP63,NDE1,TUBB,CSNK1D,DCTN1 |
| 2.178e-02 | -3.83 | Loss of proteins required for interphase microtubule organization from the centrosome | REACTOME pathways | R-HSA-380284 | 72 | 19 | 10287 | 1696 |
PLK1,FGFR1OP,MAPRE1,DYNLL1,DCTN2,HAUS4,PRKACA,HAUS2,HAUS8,PCM1,CCP110,CENPJ,ODF2,SSNA1,CEP63,NDE1,TUBB,CSNK1D,DCTN1 |
| 2.181e-02 | -3.83 | human chr1p36.11 | chromosome location | human chr1p36.11 | 87 | 16 | 26185 | 2809 |
NIPAL3,WASF2,ZDHHC18,RPS6KA1,WDTC1,ELOA,ARID1A,STMN1,PITHD1,RPL11,HMGN2,MTFR1L,CLIC4,LYPLA2,SRSF10,NUDC |
| 2.183e-02 | -3.82 | EPHA1 (EPH receptor A1) | protein interactions | 2041 | 78 | 20 | 17029 | 2761 |
NOP9,PBXIP1,NF1,PRKDC,WDR13,BTAF1,LRBA,SMC2,STK17B,GTPBP3,NUCB1,KIF14,PTPN11,TNPO2,LTN1,KNTC1,SMG9,SMURF1,CTDSP2,USP34 |
| 2.184e-02 | -3.82 | GGGYGTGNY_UNKNOWN | MSigDB lists | GGGYGTGNY_UNKNOWN | 625 | 113 | 17377 | 2626 |
TMEM106C,WASF2,UBL3,CORO7,TMEM184B,PLXNC1,TRERF1,RAB11B,ZBTB37,CAST,DYNLL1,TMX4,FKBP2,HCFC1R1,STMN1,MIEN1,CDK5,SAP130,SEC11A,APLP2,RAB8A,PSMD1,ASAP2,SAR1A,WDR44,DPYSL2,AP2B1,MTPN,ABI1,KCNAB2,GPX4,RYBP,POU2AF1,MBLAC2,NLN,MEF2D,ZMYM3,PPP2CA,TRIM47,AHNAK,ATP1A1,HNRNPR,TAB2,STAT6,ZNF367,OGT,CBWD1,ACTB,PTOV1,PARP12,PPP1R12A,C16orf87,DCTN2,FAM76A,SLC25A12,KLF13,HMGN3,ADCK5,SLC4A2,DNAJB1,SLC35B1,XPO7,WDR48,SPAG5,RTKN,JAKMIP1,FKBP1A,TFAP4,ZBTB45,CLIC4,CBWD2,ZNF335,RBM3,MRPL48,GNAI2,NCOA2,LUC7L2,MORC3,ABHD2,ADAM17,SNX2,PRRC2A,WDR1,ZMYM5,ATP2C1,MAP4K3,PACS1,BCLAF1,PLEC,WDR81,ARPC1A,RDH11,MFN2,ADSS,MTMR3,MAGED2,MOSPD3,SLCO4A1,NUCB1,KPNA4,CSK,FAM110A,TFE3,ERGIC3,DBI,MAPK6,PPP3R1,YWHAZ,FAM126A,YWHAH,PDLIM5,FAF1,SSSCA1 |
| 2.186e-02 | -3.82 | PDE6G (phosphodiesterase 6G) | protein interactions | 5148 | 11 | 5 | 17029 | 2761 |
GRK2,TRIP10,L3MBTL3,MAPK3,DNM2 |
| 2.186e-02 | -3.82 | KRT78 (keratin 78) | protein interactions | 196374 | 11 | 5 | 17029 | 2761 |
SIRT2,CYLD,UCHL5,CUL3,SRPK2 |
| 2.186e-02 | -3.82 | CHN2 (chimerin 2) | protein interactions | 1124 | 11 | 5 | 17029 | 2761 |
RB1,RACGAP1,TP53RK,RAC1,SMARCD1 |
| 2.186e-02 | -3.82 | CREG1 (cellular repressor of E1A stimulated genes 1) | protein interactions | 8804 | 11 | 5 | 17029 | 2761 |
KRAS,RB1,RBL1,CAPN1,KBTBD7 |
| 2.186e-02 | -3.82 | TRUB1 (TruB pseudouridine synthase family member 1) | protein interactions | 142940 | 11 | 5 | 17029 | 2761 |
USP11,FLYWCH2,APP,CAND1,CDC5L |
| 2.186e-02 | -3.82 | ZNF597 (zinc finger protein 597) | protein interactions | 146434 | 11 | 5 | 17029 | 2761 |
SMC6,FAM208B,NSMCE4A,MPHOSPH8,NSMCE2 |
| 2.186e-02 | -3.82 | POLD4 (DNA polymerase delta 4, accessory subunit) | protein interactions | 57804 | 11 | 5 | 17029 | 2761 |
DTL,PCNA,SEC23IP,POLE,WRNIP1 |
| 2.186e-02 | -3.82 | CYSTM1 (cysteine rich transmembrane module containing 1) | protein interactions | 84418 | 11 | 5 | 17029 | 2761 |
SLC16A1,GNAI2,RAB11A,UQCR10,TMX1 |
| 2.186e-02 | -3.82 | HIST1H2BE (histone cluster 1 H2B family member e) | protein interactions | 8344 | 11 | 5 | 17029 | 2761 |
COX15,VDAC1,MCM2,CD81,SDHA |
| 2.186e-02 | -3.82 | ATP5MC3 (ATP synthase membrane subunit c locus 3) | protein interactions | 518 | 11 | 5 | 17029 | 2761 |
GOLGA4,ATP5F1B,VKORC1,ATP5MC3,ABHD16A |
| 2.186e-02 | -3.82 | ADAMTS12 (ADAM metallopeptidase with thrombospondin type 1 motif 12) | protein interactions | 81792 | 11 | 5 | 17029 | 2761 |
CALM2,SP3,USF1,RUFY3,USF2 |
| 2.186e-02 | -3.82 | LHX9 (LIM homeobox 9) | protein interactions | 56956 | 11 | 5 | 17029 | 2761 |
SMAD2,ZHX1,SMURF1,SSBP3,LDB1 |
| 2.186e-02 | -3.82 | SLC5A5 (solute carrier family 5 member 5) | protein interactions | 6528 | 11 | 5 | 17029 | 2761 |
CTU2,ERBIN,ORMDL2,ARL5B,SFXN5 |
| 2.186e-02 | -3.82 | ZWILCH (zwilch kinetochore protein) | protein interactions | 55055 | 11 | 5 | 17029 | 2761 |
SEPT8,SNX8,KNTC1,SEPT7,ANLN |
| 2.186e-02 | -3.82 | HIST1H2AJ (histone cluster 1 H2A family member j) | protein interactions | 8331 | 11 | 5 | 17029 | 2761 |
DERL1,CUL1,MCM2,MCM5,CAND1 |
| 2.186e-02 | -3.82 | INVS (inversin) | protein interactions | 27130 | 11 | 5 | 17029 | 2761 |
CALM2,NPHP4,CHCHD6,EXT2,DDB1 |
| 2.186e-02 | -3.82 | SERP1 (stress associated endoplasmic reticulum protein 1) | protein interactions | 27230 | 11 | 5 | 17029 | 2761 |
SEC61B,SEC61A1,VKORC1,APP,LMNA |
| 2.186e-02 | -3.82 | N4BP3 (NEDD4 binding protein 3) | protein interactions | 23138 | 11 | 5 | 17029 | 2761 |
GTSE1,USP20,FGFR1OP,CAPZA2,DYNLL1 |
| 2.186e-02 | -3.82 | MRM2 (mitochondrial rRNA methyltransferase 2) | protein interactions | 29960 | 11 | 5 | 17029 | 2761 |
IMPDH1,BRCA1,TSPAN5,KBTBD7,MRPL12 |
| 2.186e-02 | -3.82 | HIST2H2BF (histone cluster 2 H2B family member f) | protein interactions | 440689 | 11 | 5 | 17029 | 2761 |
MCM2,CD81,MCM5,RBM34,MECP2 |
| 2.186e-02 | -3.82 | asp (minus-strand-encoded antisense protein of unknown function; region is highly conserved and likely analogous to the HTLV-1 encoded, HBZ, a nuclear basic region leucine zipper (b-ZIP) protein) | protein interactions | 19424028 | 11 | 5 | 17029 | 2761 |
HLA-B,USF1,MAP1LC3B,BECN1,HLA-A |
| 2.186e-02 | -3.82 | Myl12a (myosin, light chain 12A, regulatory, non-sarcomeric) | protein interactions | 67268 | 11 | 5 | 17029 | 2761 |
MYH9,EFL1,DNMT1,MYL6B,MYO18A |
| 2.186e-02 | -3.82 | SLC13A2 (solute carrier family 13 member 2) | protein interactions | 9058 | 11 | 5 | 17029 | 2761 |
SARAF,ATG9A,TWISTNB,ELOA,SRPK2 |
| 2.186e-02 | -3.82 | SPANXN3 (SPANX family member N3) | protein interactions | 139067 | 11 | 5 | 17029 | 2761 |
FBXW2,CUL1,IMPDH1,CMSS1,APP |
| 2.186e-02 | -3.82 | Wipi2 (WD repeat domain, phosphoinositide interacting 2) | protein interactions | 74781 | 11 | 5 | 17029 | 2761 |
MACF1,ATP6V0D1,PACS2,OPTN,GTF2F1 |
| 2.186e-02 | -3.82 | CXCL1 (C-X-C motif chemokine ligand 1) | protein interactions | 2919 | 11 | 5 | 17029 | 2761 |
XRCC3,PTEN,HIPK2,HRAS,SRSF1 |
| 2.186e-02 | -3.82 | AMMECR1L (AMMECR1 like) | protein interactions | 83607 | 11 | 5 | 17029 | 2761 |
FNTA,MAPK14,PGGT1B,MACF1,SRPK2 |
| 2.186e-02 | -3.82 | ALDH8A1 (aldehyde dehydrogenase 8 family member A1) | protein interactions | 64577 | 11 | 5 | 17029 | 2761 |
ADSL,CNN2,APP,MED15,SMC4 |
| 2.186e-02 | -3.82 | CAAP1 (caspase activity and apoptosis inhibitor 1) | protein interactions | 79886 | 11 | 5 | 17029 | 2761 |
JMJD6,THOC1,XRCC4,KAT7,APP |
| 2.186e-02 | -3.82 | Chmp4c (charged multivesicular body protein 4C) | protein interactions | 66371 | 11 | 5 | 17029 | 2761 |
MKNK1,MED10,KDM2A,CDCA3,DDX23 |
| 2.186e-02 | -3.82 | HIST1H2BM (histone cluster 1 H2B family member m) | protein interactions | 8342 | 11 | 5 | 17029 | 2761 |
MCM2,CD81,MCM5,APP,H2AFX |
| 2.186e-02 | -3.82 | CMYA5 (cardiomyopathy associated 5) | protein interactions | 202333 | 11 | 5 | 17029 | 2761 |
EPRS,FOXK1,MCM2,PPME1,PSMC4 |
| 2.186e-02 | -3.82 | FABP3 (fatty acid binding protein 3) | protein interactions | 2170 | 11 | 5 | 17029 | 2761 |
PLK1,FKBP1A,NUP62,TAGLN2,HINT1 |
| 2.186e-02 | -3.82 | BLID (BH3-like motif containing, cell death inducer) | protein interactions | 414899 | 11 | 5 | 17029 | 2761 |
TGFB1,BCL2,BCL2L1,RB1CC1,HRAS |
| 2.186e-02 | -3.82 | FBXO22 (F-box protein 22) | protein interactions | 26263 | 11 | 5 | 17029 | 2761 |
CUL1,NCOR2,COPS6,RBX1,CENPJ |
| 2.186e-02 | -3.82 | TNFRSF10C (TNF receptor superfamily member 10c) | protein interactions | 8794 | 11 | 5 | 17029 | 2761 |
RAP1A,ZHX1,LRSAM1,LMNA,SRPK2 |
| 2.186e-02 | -3.82 | FGL2 (fibrinogen like 2) | protein interactions | 10875 | 11 | 5 | 17029 | 2761 |
ZNF282,CYLD,SPATA2,GNPDA1,FUT8 |
| 2.186e-02 | -3.82 | HIST1H2AI (histone cluster 1 H2A family member i) | protein interactions | 8329 | 11 | 5 | 17029 | 2761 |
CUL1,BLM,PCGF1,MCM2,CAND1 |
| 2.186e-02 | -3.82 | B4galt1 (UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1) | protein interactions | 14595 | 11 | 5 | 17029 | 2761 |
MRPL54,B4GALT1,SLC35B1,PARP10,DLGAP4 |
| 2.186e-02 | -3.82 | RMI2 (RecQ mediated genome instability 2) | protein interactions | 116028 | 11 | 5 | 17029 | 2761 |
CCDC69,BLM,RMI1,FAAP100,TOP3A |
| 2.186e-02 | -3.82 | DECR2 (2,4-dienoyl-CoA reductase 2) | protein interactions | 26063 | 11 | 5 | 17029 | 2761 |
RNASEH2A,PEX5,SESTD1,APP,GLMP |
| 2.186e-02 | -3.82 | UNC13D (unc-13 homolog D) | protein interactions | 201294 | 11 | 5 | 17029 | 2761 |
ANXA5,DPYSL2,AACS,PICALM,LMNA |
| 2.188e-02 | -3.82 | COLDREN_GEFITINIB_RESISTANCE_UP | MSigDB lists | COLDREN_GEFITINIB_RESISTANCE_UP | 73 | 18 | 17377 | 2626 |
PPIF,COX15,NOL8,PCGF6,BMS1,IKBIP,SRRT,USP36,IDE,NAP1L1,IARS,KLHL15,CEBPG,WDR62,PDCD11,TRAF5,UBE2M,TIMM50 |
| 2.188e-02 | -3.82 | CROMER_METASTASIS_UP | MSigDB lists | CROMER_METASTASIS_UP | 73 | 18 | 17377 | 2626 |
TCF12,PPT1,EID1,TSC22D3,MAGED1,TMEM109,ARHGDIB,PSMB9,REEP5,SLC25A36,MAGED2,SH3BP5,GNS,WAS,PGRMC1,RPN2,KIFAP3,PTPRK |
| 2.188e-02 | -3.82 | MORF_ARAF1 | MSigDB lists | MORF_ARAF1 | 73 | 18 | 17377 | 2626 |
PDPK1,LUZP1,RPLP2,PRKCSH,KAT7,AGPAT1,RPS24,MTX1,TUBGCP2,GTF2F1,RXRB,ARHGEF1,PML,COPS6,B4GALT3,USP11,LYPLA2,NUDT3 |
| 2.188e-02 | -3.82 | PEART_HDAC_PROLIFERATION_CLUSTER_DN | MSigDB lists | PEART_HDAC_PROLIFERATION_CLUSTER_DN | 73 | 18 | 17377 | 2626 |
PLK1,NF1,ZMYND11,TLK1,ILF3,CUL1,EMP3,CTCF,PA2G4,ZNF330,MCM5,TFDP1,KNTC1,TFDP2,UBE2C,CCNB2,IFI16,RAD51D |
| 2.188e-02 | -3.82 | GO_VASCULAR_ENDOTHELIAL_GROWTH_FACTOR_RECEPTOR_SIGNALING_PATHWAY | MSigDB lists | GO_VASCULAR_ENDOTHELIAL_GROWTH_FACTOR_RECEPTOR_SIGNALING_PATHWAY | 73 | 18 | 17377 | 2626 |
WASF2,CYFIP1,RHOA,NCK1,MAPKAPK3,VAV2,RAC1,NCKAP1,CYFIP2,MAPK14,VAV1,PDCD6,CDC42,ELMO1,PIK3R2,ACTB,ROCK1,ABI1 |
| 2.188e-02 | -3.82 | BIOCARTA_KREB_PATHWAY | MSigDB lists | BIOCARTA_KREB_PATHWAY | 8 | 4 | 17377 | 2626 |
MDH1,OGDH,SDHA,CS |
| 2.188e-02 | -3.82 | NIKOLSKY_BREAST_CANCER_10Q22_AMPLICON | MSigDB lists | NIKOLSKY_BREAST_CANCER_10Q22_AMPLICON | 8 | 4 | 17377 | 2626 |
DLG5,RPS24,PPIF,ZMIZ1 |
| 2.189e-02 | -3.82 | N-acyltransferase activity | molecular function | GO:0016410 | 103 | 24 | 17224 | 2647 |
GNPNAT1,KAT2A,KAT7,ELP4,EDF1,TAF6L,USP22,WDR5,SUPT7L,NMT2,CERS6,TEX30,OGT,NAA50,TAF5L,KANSL2,TAF12,NCOA1,NAA20,ATF2,SMARCE1,NAA35,SAT2,NAA60 |
| 2.190e-02 | -3.82 | KIF5B (kinesin family member 5B) | protein interactions | 3799 | 113 | 27 | 17029 | 2761 |
STAU1,CAST,COPE,MCCC1,TRAK1,DHX9,PSMB7,KLC1,AURKB,BRCA1,VDAC1,MARK2,KTN1,PSMB3,XPR1,HOMER1,HUWE1,SNAP23,RRBP1,OGT,YWHAZ,SLC38A10,ECPAS,YWHAH,SGF29,NCOA2,CDC5L |
| 2.191e-02 | -3.82 | protein polymerization | biological process | GO:0051258 | 83 | 20 | 17256 | 2622 |
ZNF207,CHMP2A,CORO7,MZT1,RAC1,TUBGCP5,TUBGCP2,FBXO5,MID1IP1,WAS,CHMP4A,GOLGA2,CENPJ,PIN1,DNM2,TTC17,NDE1,UBE2C,CSNK1D,GPX4 |
| 2.191e-02 | -3.82 | GO_REGULATION_OF_GLUCOSE_TRANSPORT | MSigDB lists | GO_REGULATION_OF_GLUCOSE_TRANSPORT | 94 | 22 | 17377 | 2626 |
NUP188,AKT2,RAE1,PRKAA1,NUP54,CREBL2,NUP155,MAPK14,APPL1,NUP205,RAP1A,NUP210,OSBPL8,PIK3R2,NUP107,PTPN11,NUP62,NUP153,RNASEL,NUP85,SEH1L,AAAS |
| 2.191e-02 | -3.82 | MODULE_486 | MSigDB lists | MODULE_486 | 94 | 22 | 17377 | 2626 |
TSC2,RAB11B,SF3B1,MUM1,ARGLU1,CDC6,CHKB,CCNL2,CCNF,STMN1,SPPL2B,DDX17,SLC19A1,PEX5,HDAC7,INTS1,LUC7L3,DDX5,SNRNP70,MYO9A,TAF6,ARHGAP23 |
| 2.192e-02 | -3.82 | - | gene3d domains | 2.60.200.10 | 15 | 6 | 8148 | 1295 |
IRF4,IRF3,SMAD2,SMAD1,SMAD4,IRF5 |
| 2.194e-02 | -3.82 | MRPS2 (mitochondrial ribosomal protein S2) | protein interactions | 51116 | 54 | 15 | 17029 | 2761 |
TPD52L2,DAP3,RBM42,MRPS15,GRSF1,ZNF746,RPL6,MRPS27,TRMT10B,DUSP11,OGDH,MRPS14,ZC3H3,APP,CAND1 |
| 2.194e-02 | -3.82 | ZNF326 (zinc finger protein 326) | protein interactions | 284695 | 54 | 15 | 17029 | 2761 |
SUZ12,SF3B1,SF3B6,BUD31,ILF3,CUL3,BRCA1,CNTROB,SEPT7,MATR3,HNRNPM,POLR2A,SRSF1,CAND1,HP1BP3 |
| 2.194e-02 | -3.82 | OLA1 (Obg like ATPase 1) | protein interactions | 29789 | 54 | 15 | 17029 | 2761 |
HSPA4,MAPRE1,EWSR1,NDUFA2,HUWE1,LSM8,PRPF4,YWHAZ,PRPF3,BRCA1,NDUFA7,ARPC1A,BCAP31,TUBB,WWP2 |
| 2.194e-02 | -3.82 | ARHGAP1 (Rho GTPase activating protein 1) | protein interactions | 392 | 54 | 15 | 17029 | 2761 |
LARS,WAS,RHOA,CDC42,AGTRAP,RHOC,RAC1,PTPN11,CAPZA1,TMEM216,CHEK2,RUVBL2,AP1B1,NMD3,PFKP |
| 2.194e-02 | -3.82 | SLC25A11 (solute carrier family 25 member 11) | protein interactions | 8402 | 54 | 15 | 17029 | 2761 |
COX15,STAU1,COPA,SUZ12,ZNF746,BABAM1,VDAC2,FLOT1,NDUFA4,ACTB,ADRB2,CLN3,MCM2,VDAC1,SMAP2 |
| 2.196e-02 | -3.82 | proteasome storage granule | cellular component | GO:0034515 | 2 | 2 | 18223 | 2701 |
PSMD2,PSMD1 |
| 2.196e-02 | -3.82 | methionine adenosyltransferase complex | cellular component | GO:0048269 | 2 | 2 | 18223 | 2701 |
MAT2B,MAT2A |
| 2.196e-02 | -3.82 | RSC-type complex | cellular component | GO:0016586 | 2 | 2 | 18223 | 2701 |
PBRM1,SUZ12 |
| 2.196e-02 | -3.82 | Rix1 complex | cellular component | GO:0097344 | 2 | 2 | 18223 | 2701 |
TEX10,WDR18 |
| 2.196e-02 | -3.82 | Rad51C-XRCC3 complex | cellular component | GO:0033065 | 2 | 2 | 18223 | 2701 |
XRCC3,RAD51C |
| 2.196e-02 | -3.82 | CAAX-protein geranylgeranyltransferase complex | cellular component | GO:0005953 | 2 | 2 | 18223 | 2701 |
FNTA,PGGT1B |
| 2.196e-02 | -3.82 | cyclin A2-CDK2 complex | cellular component | GO:0097124 | 2 | 2 | 18223 | 2701 |
CCNA2,CDK2 |
| 2.196e-02 | -3.82 | nuclear MIS12/MIND complex | cellular component | GO:0000818 | 2 | 2 | 18223 | 2701 |
DSN1,MIS12 |
| 2.196e-02 | -3.82 | MutSalpha complex | cellular component | GO:0032301 | 2 | 2 | 18223 | 2701 |
MSH6,MSH2 |
| 2.196e-02 | -3.82 | cyclin K-CDK12 complex | cellular component | GO:0002944 | 2 | 2 | 18223 | 2701 |
CCNK,CDK12 |
| 2.196e-02 | -3.82 | cyclin K-CDK13 complex | cellular component | GO:0002945 | 2 | 2 | 18223 | 2701 |
CCNK,CDK13 |
| 2.196e-02 | -3.82 | endosome to plasma membrane transport vesicle | cellular component | GO:0070381 | 2 | 2 | 18223 | 2701 |
RAB6A,PICALM |
| 2.202e-02 | -3.82 | phosphoprotein binding | molecular function | GO:0051219 | 77 | 19 | 17224 | 2647 |
CSNK1G2,PRKCSH,VAV2,RTF1,THRAP3,PHF6,EPB41,MAPK3,VAV1,ABL2,CRKL,RB1,SHC1,PIN1,PIK3R2,PTPN11,PKD2,MAPK1,CBX4 |
| 2.205e-02 | -3.81 | GSE30971_WBP7_HET_VS_KO_MACROPHAGE_2H_LPS_STIM_DN | MSigDB lists | GSE30971_WBP7_HET_VS_KO_MACROPHAGE_2H_LPS_STIM_DN | 182 | 38 | 17377 | 2626 |
TRIP10,PLAGL2,AGFG1,THRAP3,KTN1,TFRC,SLC25A37,RBM17,PTPN2,VAV1,ASAP2,TNFAIP8,ITGB8,PTEN,FJX1,TP53BP2,PIKFYVE,LDLRAD3,STAT3,ANKLE2,ENPP4,ETV3,ELL2,MAP4K4,HEBP2,MRPS10,PNPLA8,KLF6,ZFR,MAP3K4,SLCO4A1,SURF4,GADD45B,FAM126A,FBXL3,MAP3K5,RPS6KC1,CDKN2A |
| 2.205e-02 | -3.81 | GSE40274_LEF1_VS_FOXP3_AND_LEF1_TRANSDUCED_ACTIVATED_CD4_TCELL_DN | MSigDB lists | GSE40274_LEF1_VS_FOXP3_AND_LEF1_TRANSDUCED_ACTIVATED_CD4_TCELL_DN | 182 | 38 | 17377 | 2626 |
DDX58,GMFG,TRIO,STARD7,SNRPD3,SLC25A44,COMMD8,APP,PIP4K2A,KIAA1147,HERC3,ADD3,SIAH1,CD3EAP,F2R,ZNF770,PACS2,UBE2QL1,ORAI2,ETV3,TSPYL4,EMB,HSDL1,THNSL1,ICAM2,CBFB,STK17B,GEMIN5,PPP2R5A,STK38,WNT5B,IMPDH1,FAM122A,ACAT1,SMG9,TSPAN5,EYA2,NUMB |
| 2.205e-02 | -3.81 | KIM_MYC_AMPLIFICATION_TARGETS_UP | MSigDB lists | KIM_MYC_AMPLIFICATION_TARGETS_UP | 182 | 38 | 17377 | 2626 |
KARS,NDUFS1,SUCLG1,MRPS2,NDUFAF2,CYCS,POLR3K,PARK7,RPL11,MCTS1,EEF2K,MRPL50,LYAR,EIF2S2,GOT2,AKR1B1,FBL,WDR41,LDHB,IDH3A,LYRM1,PSMG1,GALK2,ODC1,SLC25A5,MAK16,RHOB,RPSA,DAP3,NIP7,ACLY,PGRMC1,LRPPRC,SLC16A1,GPI,MRPL13,NUDT11,SLC25A39 |
| 2.205e-02 | -3.81 | GSE3982_MAST_CELL_VS_NKCELL_UP | MSigDB lists | GSE3982_MAST_CELL_VS_NKCELL_UP | 182 | 38 | 17377 | 2626 |
PKP4,MRPL42,ADO,CUTA,LAGE3,ZFYVE21,NDUFA4,SNRPD3,SNN,AP3S1,BZW2,LMNA,ZNF804A,PSMD1,CLIC4,PPP6C,TNPO3,TALDO1,MOB1A,SOCS5,RHOBTB3,MRPS10,UTP3,SOX4,MCFD2,UTP20,PPP2CA,DAP3,HSPA4,PRDX3,CERS6,LSM6,SIL1,ADAM9,TMEM14A,NMD3,ABCA1,RTN3 |
| 2.205e-02 | -3.81 | GSE1460_CD4_THYMOCYTE_VS_THYMIC_STROMAL_CELL_DN | MSigDB lists | GSE1460_CD4_THYMOCYTE_VS_THYMIC_STROMAL_CELL_DN | 182 | 38 | 17377 | 2626 |
GCLM,EYA1,WDYHV1,UCK2,PLXNA1,POMP,COPB2,DLG5,CD59,C12orf10,EIF2S2,IMPAD1,RRBP1,RAD23B,TPST1,TFG,STRAP,NUDC,SAP30,PDLIM2,POLR2L,CREG1,RABIF,ATXN1,MCFD2,MAP2K2,PDHX,TARS,DERL1,CHCHD3,PON2,UAP1,TFE3,SIL1,SLC16A1,COPS6,PDLIM5,PTOV1 |
| 2.205e-02 | -3.81 | GSE32986_CURDLAN_HIGHDOSE_VS_GMCSF_AND_CURDLAN_HIGHDOSE_STIM_DC_UP | MSigDB lists | GSE32986_CURDLAN_HIGHDOSE_VS_GMCSF_AND_CURDLAN_HIGHDOSE_STIM_DC_UP | 182 | 38 | 17377 | 2626 |
UBL3,NAT9,GLT8D1,HEXB,RRAGC,CHKB,HCFC1R1,PSEN1,HMG20A,MXD1,RFWD3,PDK2,LPIN2,CNPY4,CDKN1B,ANAPC7,MAVS,PLCL2,DNMT1,NCOA2,CGGBP1,DCAF6,TMEM126B,PLEKHM3,RIT1,SMC2,CYFIP2,USP21,RPA1,GOLGA2,RBL1,GLG1,SIL1,ASNA1,RNASEL,WDR62,ATP6V1C1,CHPT1 |
| 2.205e-02 | -3.81 | GSE3982_BCELL_VS_NKCELL_UP | MSigDB lists | GSE3982_BCELL_VS_NKCELL_UP | 182 | 38 | 17377 | 2626 |
LYRM4,REPS2,TOR3A,TCF3,ADO,RPL15,PPP1R16B,RPAIN,PABPC4,IRF4,TNS3,CLIC4,THADA,TBC1D22A,RAD23B,MRPS27,PPP6C,PPA1,PTPRK,LDHB,ATP6V1G1,FDFT1,EIF3L,CCT2,HEMK1,NSDHL,CIRBP,EZR,UTP3,CBFA2T2,CLNS1A,GNA12,DAP3,FBXO41,PDLIM1,CCDC6,HPS5,LTA4H |
| 2.205e-02 | -3.81 | GSE25123_CTRL_VS_IL4_STIM_MACROPHAGE_UP | MSigDB lists | GSE25123_CTRL_VS_IL4_STIM_MACROPHAGE_UP | 182 | 38 | 17377 | 2626 |
CYTIP,AGTRAP,GNPDA1,UQCR10,HEXB,CERK,MYH9,OAT,DUSP22,SPAG5,EBP,JAKMIP1,GNS,APLP2,MED10,NDUFB4,MCM5,SSBP3,ZNF335,PDCD2,S100A6,RNF169,PTPN18,EXOSC6,COQ10B,PSMB7,RFXANK,PCGF6,NDUFB1,GAR1,DDOST,PDRG1,HIPK2,MRPL27,PSAP,TERF1,RNF139,IFI16 |
| 2.208e-02 | -3.81 | GAR1 (GAR1 ribonucleoprotein) | protein interactions | 54433 | 83 | 21 | 17029 | 2761 |
UBXN1,USP10,NLN,USP39,DDX20,BRCA1,LRRC1,MAK16,CLNS1A,LMNA,CAND1,GEMIN5,PTPN2,MRPL50,KEAP1,SYNCRIP,CTR9,GEMIN4,SNRNP70,GPATCH4,SAP30 |
| 2.208e-02 | -3.81 | SNX3 (sorting nexin 3) | protein interactions | 8724 | 83 | 21 | 17029 | 2761 |
DYNLL1,RAB7A,USP10,BRCA1,NDUFA7,ARL6IP6,GLOD4,SUGP1,HGS,NDUFA2,SETD3,PIN1,PPM1G,CTPS1,ARL6IP1,RBMS1,TAGLN2,TFG,AHCYL1,IGBP1,KCNAB2 |
| 2.211e-02 | -3.81 | GO_CYTOSOLIC_TRANSPORT | MSigDB lists | GO_CYTOSOLIC_TRANSPORT | 199 | 41 | 17377 | 2626 |
RAB14,ANKRD27,CORO7,DNAJC5,SYS1,AP3M2,VTI1A,TGOLN2,RAB6A,ARF1,AP3S1,PSEN1,PIP5K1C,CDK5,KLHL20,AP3S2,DPYSL2,TBC1D14,DNM2,CORO1A,LMAN1,PIKFYVE,SYTL3,DCTN1,SRSF10,SNX8,GCC2,RHOBTB3,SNX2,RAB7A,STX16,GOSR1,ERC1,TBC1D17,SURF4,VPS26B,SNAP29,SNAP23,AP1S1,VPS29,SNAPIN |
| 2.211e-02 | -3.81 | cell cortex region | cellular component | GO:0099738 | 34 | 10 | 18223 | 2701 |
RIMS3,PKD2,ANLN,CLTB,MYL12B,UNC13C,GM2A,SAPCD2,DCTN1,EPB41 |
| 2.212e-02 | -3.81 | Mismatch repair | KEGG pathways | ko03430 | 23 | 8 | 7161 | 1149 |
RPA2,RFC3,PCNA,PMS2,MSH2,RFC2,MSH6,RPA1 |
| 2.212e-02 | -3.81 | Mismatch repair | KEGG pathways | hsa03430 | 23 | 8 | 7161 | 1149 |
RPA2,PCNA,RFC3,PMS2,MSH2,RFC2,MSH6,RPA1 |
| 2.214e-02 | -3.81 | enzyme linked receptor protein signaling pathway | biological process | GO:0007167 | 725 | 130 | 17256 | 2622 |
RAB14,TSC2,SIRT2,MAPK14,ABL2,CDC42,IL6ST,PIK3R2,ZFYVE27,AP2B1,TIPARP,CDC37,PTPRK,NRAS,PTPN18,KLF10,NCK1,APH1A,AKT2,HNRNPF,ZFAND5,ARF4,SMAD2,RPS27A,ITGB1,ADAM9,ATP6V0C,ACTB,ROCK1,SMAD1,ARRB2,ATP6V0E1,C2CD5,PDCD4,UBE2D3,POLR2K,TRIO,VAV2,SDC2,TIA1,NCKAP1,ITGB5,APH1B,PSEN1,FKBP1A,SUB1,NUS1,ARPC5,MEGF8,ATP6V0A2,MVP,ATP6V0D1,SOCS5,CYFIP1,POLR2I,MAPKAPK3,KRAS,ADRB2,CYFIP2,ARPC1A,APPL1,PTPRF,FNTA,POLR2J,CSK,TOB1,WASF2,REPS2,RAF1,ACTR3,RAC1,ATP6V1B2,STMN1,LYN,DUSP22,CPNE3,VAV1,PDK2,ATP6V0B,SHC1,MTMR4,CD3EAP,ABI1,ATP6V1G1,SHOC2,POLR2L,POLR2G,POLR2D,ATP6V0A1,ERBIN,SHCBP1,GIGYF1,SOCS7,IDE,JAK1,HIPK2,MAPK1,SMURF1,SMAD4,AP2S1,PARD3,AKT1S1,AP3S1,GTF2F1,PTPN2,FGFR3,PTEN,FUT8,PTPN11,CREB1,CITED2,STAT3,UBE2M,HNRNPM,TGFB1,PDPK1,ADAM17,RHOA,POLR2A,MAPK3,ATP6V1D,PDCD6,LTBP4,TWSG1,ELMO1,PML,DDX5,ATP6V1C1,HRAS,FAM83G |
| 2.220e-02 | -3.81 | GIGYF2 (GRB10 interacting GYF protein 2) | protein interactions | 26058 | 103 | 25 | 17029 | 2761 |
NF1,DENND4C,SNRPB,AGO2,MRPL12,DDX20,AURKB,FXR1,MCM2,GIGYF1,SF3B2,RTKN,CNOT9,MAGED2,ZBTB21,EXOSC7,MEX3C,HUWE1,KIF13B,YBX1,TARDBP,GEMIN4,USP11,ZNF598,PABPC1 |
| 2.220e-02 | -3.81 | PDGFRB (platelet derived growth factor receptor beta) | protein interactions | 5159 | 103 | 25 | 17029 | 2761 |
NOP9,ANKLE2,PDCD6IP,COPA,DEPDC1,FOXK1,SNX2,NCK1,RAF1,PDAP1,VAV2,TYW1,BCLAF1,PDE3B,PTPN2,VAV1,SHC1,JAK1,GRK2,PTEN,PIK3R2,ETV6,STAT1,PTPN11,STAT3 |
| 2.220e-02 | -3.81 | RAD50 (RAD50 double strand break repair protein) | protein interactions | 10111 | 103 | 25 | 17029 | 2761 |
FGFR1OP,SUMO2,USP42,ILF3,NFATC2,BRCA1,DCLRE1C,BLM,RPA1,TERF2IP,TFAP4,RPA2,MDM2,HNRNPR,MCM5,MSH2,H2AFX,CHEK2,USP11,USP53,TERF1,MSH6,TERF2,ZNF511,CDC5L |
| 2.221e-02 | -3.81 | GSE40274_CTRL_VS_FOXP3_AND_PBX1_TRANSDUCED_ACTIVATED_CD4_TCELL_DN | MSigDB lists | GSE40274_CTRL_VS_FOXP3_AND_PBX1_TRANSDUCED_ACTIVATED_CD4_TCELL_DN | 143 | 31 | 17377 | 2626 |
PLK3,EXOC3,HMGN1,CSRP1,UFC1,ILF3,EDF1,CHMP2B,ZFAND5,CHCHD6,PSMB3,RBM38,PRDX1,PIP5K1C,RBM17,RFWD3,EIF3K,CXXC4,IRF4,ERH,HOMER1,PSMA6,IDE,E2F1,BRI3,RBPJ,MYBL1,NDUFA3,SLC25A39,LYPLA2,TIMM50 |
| 2.222e-02 | -3.81 | TAF9 (TATA-box binding protein associated factor 9) | protein interactions | 6880 | 88 | 22 | 17029 | 2761 |
KAT2A,DRAP1,DHX8,RPS24,NFATC2,TAF6L,USP22,SUPT7L,KLF6,APP,TFEB,TAF2,ALDH3B1,KPNA1,RPS14,TAF5L,TAF12,RUVBL2,FBL,TAF6,COIL,NCOA2 |
| 2.222e-02 | -3.81 | MVP (major vault protein) | protein interactions | 9961 | 88 | 22 | 17029 | 2761 |
CYLD,GOPC,PARP4,DHX9,KRAS,BRCA1,RAB3IP,MCM2,EPHX2,RCOR3,GIT2,GOLGA2,PTEN,PTPN11,GTSE1,YBX1,CHMP4B,KPNA2,PSAP,MVP,POT1,CDC5L |
| 2.222e-02 | -3.81 | HSPBP1 (HSPA (Hsp70) binding protein 1) | protein interactions | 23640 | 88 | 22 | 17029 | 2761 |
MKLN1,FLYWCH2,DRAP1,ERO1A,AGFG1,RUFY1,EDRF1,APP,SH3GLB1,HSPA1B,EVC2,ABL2,HGS,HSPA4,PPME1,UBXN2B,WDR4,OGT,LRSAM1,NMD3,TACC3,CSTF1 |
| 2.223e-02 | -3.81 | GO_REGULATION_OF_WNT_SIGNALING_PATHWAY | MSigDB lists | GO_REGULATION_OF_WNT_SIGNALING_PATHWAY | 297 | 58 | 17377 | 2626 |
ZBED3,NPHP4,CYLD,TSC2,XIAP,NKD2,CSNK2A1,SMARCA4,ZNRF3,CSNK1A1,PSMD9,MAPK14,FOXO3,SCYL2,CDC73,MAD2L2,FZD6,PSMD2,PSMD1,PSMA6,PIN1,MBD2,AXIN2,MDFIC,ZRANB1,DVL2,USP34,PSMA8,RBX1,ASPM,CUL3,PSMB7,PSMA1,LRP5,SOX4,MACF1,PSMB9,PSMB3,DAPK3,PSMC4,ANKRD10,CXXC4,PPP2CA,HHEX,PFDN5,RPS27A,PSMD8,WNT5B,AXIN1,PSMD3,ARNTL,SIAH2,ATP6V0C,STK11,RBPJ,DVL1,PSMC1,CSNK1D |
| 2.224e-02 | -3.81 | MITSIADES_RESPONSE_TO_APLIDIN_UP | MSigDB lists | MITSIADES_RESPONSE_TO_APLIDIN_UP | 403 | 76 | 17377 | 2626 |
NAT9,CYTIP,TSC22D3,MAP1LC3B,RBM4,MIS12,CREM,TERF2IP,JOSD1,NFU1,CHTOP,F2R,SCYL3,RYBP,CDKN2AIP,CLCN3,ATG9A,NARF,MTMR6,EZR,ATP6V0A1,PFKFB3,MCL1,EAF2,STK17B,USP36,ARF4,CHMP4A,JAK1,BRD2,SPATA2,CLK3,GADD45B,RBMS1,PRPF4,H3F3A,ATP6V0E1,NCOR2,PPP1R2,KLHL21,ZCCHC8,FAM53C,HLA-E,TOR3A,JMJD6,IP6K2,RGS2,YY1AP1,CHKA,CTSS,CLDND1,PIK3IP1,TTC17,MAP3K14,MORC3,MOB4,IFRD1,TYW1,MAP4K3,SRSF5,KLF6,GOSR1,STYXL1,PDE3B,KDM3A,RHOB,BSDC1,POLR2A,GNAS,SLCO4A1,MBIP,NEK1,USP20,DUSP11,N4BP2L2,RNF114 |
| 2.224e-02 | -3.81 | Sin3-type complex | cellular component | GO:0070822 | 16 | 6 | 18223 | 2701 |
CSNK2A1,SAP130,BRMS1,RBBP4,SINHCAF,HDAC2 |
| 2.224e-02 | -3.81 | U2-type precatalytic spliceosome | cellular component | GO:0071005 | 16 | 6 | 18223 | 2701 |
SART1,PRPF4,PRPF3,SNRPB,SF3B1,SMU1 |
| 2.225e-02 | -3.81 | CTTNBP2 (cortactin binding protein 2) | protein interactions | 83992 | 27 | 9 | 17029 | 2761 |
MOB4,PPP2CA,CCT2,PDCD10,STRIP1,STRN4,KRAS,ZRANB1,CCT8 |
| 2.225e-02 | -3.81 | TGIF2LY (TGFB induced factor homeobox 2 like, Y-linked) | protein interactions | 90655 | 27 | 9 | 17029 | 2761 |
MBIP,RALB,DPYSL2,PBK,LRP5,THNSL1,OGFR,AHCYL1,PDCD4 |
| 2.225e-02 | -3.81 | UL27 (protein UL27) | protein interactions | 3077449 | 27 | 9 | 17029 | 2761 |
PSMD2,HNRNPH3,PSMD3,ACLY,RUVBL2,RAB1A,STAT3,DDB1,PSMC4 |
| 2.225e-02 | -3.81 | C2CD5 (C2 calcium dependent domain containing 5) | protein interactions | 9847 | 27 | 9 | 17029 | 2761 |
CDK5,SYNCRIP,RBM8A,RACGAP1,CDK2,SASS6,PPP6R1,QSOX2,RXRB |
| 2.225e-02 | -3.81 | MKL1 (megakaryoblastic leukemia (translocation) 1) | protein interactions | 57591 | 27 | 9 | 17029 | 2761 |
SMARCA4,ACTB,CEP63,UBE2I,MVP,KDM3A,DNMT1,SSRP1,SUPT16H |
| 2.225e-02 | -3.81 | LAMTOR1 (late endosomal/lysosomal adaptor, MAPK and MTOR activator 1) | protein interactions | 55004 | 27 | 9 | 17029 | 2761 |
GNAS,ZNRF2,LIMK1,LAMTOR4,LAMTOR3,RRAGC,DUSP22,CAPN1,XRCC5 |
| 2.225e-02 | -3.81 | SFTPC (surfactant protein C) | protein interactions | 6440 | 27 | 9 | 17029 | 2761 |
PHC2,DNAJC10,SEC61G,PQBP1,ATP6V0A2,SCARB1,DNAJB9,LMNA,WWP2 |
| 2.225e-02 | -3.81 | MRPL30 (mitochondrial ribosomal protein L30) | protein interactions | 51263 | 27 | 9 | 17029 | 2761 |
MRPL50,ZNF317,MRPL9,MRPL42,MRPL39,MRPL12,RPL6,KRAS,ZC3H3 |
| 2.225e-02 | -3.81 | TMUB1 (transmembrane and ubiquitin like domain containing 1) | protein interactions | 83590 | 27 | 9 | 17029 | 2761 |
RAB7A,RANGAP1,ADRB2,SYVN1,WBP1,DUSP22,APP,TSPAN5,RNF139 |
| 2.225e-02 | -3.81 | CRTC3 (CREB regulated transcription coactivator 3) | protein interactions | 64784 | 27 | 9 | 17029 | 2761 |
ZBTB21,MDM2,EWSR1,CENPJ,KIF13B,SCYL1,GTSE1,MCM2,LRP8 |
| 2.225e-02 | -3.81 | LRIG1 (leucine rich repeats and immunoglobulin like domains 1) | protein interactions | 26018 | 27 | 9 | 17029 | 2761 |
CANT1,PON2,MTFR1L,HGS,CNPY3,HLA-E,RAB4A,CNPY4,PTPRK |
| 2.225e-02 | -3.81 | WASF3 (WAS protein family member 3) | protein interactions | 10810 | 27 | 9 | 17029 | 2761 |
CYFIP1,PIK3R2,ACTR3,CENPF,ACTB,NCKAP1,CYFIP2,ABI1,TIMM50 |
| 2.225e-02 | -3.81 | Ring1 (ring finger protein 1) | protein interactions | 19763 | 27 | 9 | 17029 | 2761 |
PHC2,USP7,CHMP2A,PCGF6,PCGF1,WDR5,CBX4,RYBP,FBRS |
| 2.225e-02 | -3.81 | SUPT4H1 (SPT4 homolog, DSIF elongation factor subunit) | protein interactions | 6827 | 27 | 9 | 17029 | 2761 |
NAP1L1,EWSR1,PDLIM1,EIF3D,ANXA5,CSNK2A1,APP,POLR2A,XRCC5 |
| 2.226e-02 | -3.80 | RNA_POL_M_15KD | pfam domains | PF02150 | 2 | 2 | 17054 | 2545 |
POLR2I,POLR3K |
| 2.226e-02 | -3.80 | Glycohydro_20b2 | pfam domains | PF14845 | 2 | 2 | 17054 | 2545 |
HEXA,HEXB |
| 2.226e-02 | -3.80 | B12-binding | pfam domains | PF02310 | 2 | 2 | 17054 | 2545 |
MUT,MTR |
| 2.226e-02 | -3.80 | GalKase_gal_bdg | pfam domains | PF10509 | 2 | 2 | 17054 | 2545 |
GALK1,GALK2 |
| 2.226e-02 | -3.80 | tRNA-synt_1c_C | pfam domains | PF03950 | 2 | 2 | 17054 | 2545 |
EPRS,QARS |
| 2.226e-02 | -3.80 | DUF3512 | pfam domains | PF12024 | 2 | 2 | 17054 | 2545 |
BRD7,BRD9 |
| 2.226e-02 | -3.80 | FGE-sulfatase | pfam domains | PF03781 | 2 | 2 | 17054 | 2545 |
SUMF1,SUMF2 |
| 2.226e-02 | -3.80 | PSP | pfam domains | PF04046 | 2 | 2 | 17054 | 2545 |
ZCCHC8,SF3B2 |
| 2.226e-02 | -3.80 | LAP1C | pfam domains | PF05609 | 2 | 2 | 17054 | 2545 |
TOR1AIP2,TOR1AIP1 |
| 2.226e-02 | -3.80 | XPC-binding | pfam domains | PF09280 | 2 | 2 | 17054 | 2545 |
RAD23B,RAD23A |
| 2.226e-02 | -3.80 | SIKE | pfam domains | PF05769 | 2 | 2 | 17054 | 2545 |
SIKE1,FGFR1OP2 |
| 2.226e-02 | -3.80 | Citrate_synt | pfam domains | PF00285 | 2 | 2 | 17054 | 2545 |
CS,ACLY |
| 2.226e-02 | -3.80 | SAP30_Sin3_bdg | pfam domains | PF13867 | 2 | 2 | 17054 | 2545 |
SAP30L,SAP30 |
| 2.226e-02 | -3.80 | PDCD2_C | pfam domains | PF04194 | 2 | 2 | 17054 | 2545 |
PDCD2,PDCD2L |
| 2.226e-02 | -3.80 | zf-SAP30 | pfam domains | PF13866 | 2 | 2 | 17054 | 2545 |
SAP30L,SAP30 |
| 2.226e-02 | -3.80 | Pyrophosphatase | pfam domains | PF00719 | 2 | 2 | 17054 | 2545 |
PPA1,PPA2 |
| 2.226e-02 | -3.80 | Pacs-1 | pfam domains | PF10254 | 2 | 2 | 17054 | 2545 |
PACS1,PACS2 |
| 2.226e-02 | -3.80 | Coatomer_WDAD | pfam domains | PF04053 | 2 | 2 | 17054 | 2545 |
COPA,COPB2 |
| 2.226e-02 | -3.80 | TAF6_C | pfam domains | PF07571 | 2 | 2 | 17054 | 2545 |
TAF6L,TAF6 |
| 2.226e-02 | -3.80 | Sec2p | pfam domains | PF06428 | 2 | 2 | 17054 | 2545 |
RAB3IP,RAB3IL1 |
| 2.226e-02 | -3.80 | RNA_pol_Rpb1_R | pfam domains | PF05001 | 2 | 2 | 17054 | 2545 |
ZNF768,POLR2A |
| 2.226e-02 | -3.80 | DUF1897 | pfam domains | PF09005 | 2 | 2 | 17054 | 2545 |
KHSRP,FUBP1 |
| 2.226e-02 | -3.80 | PRP4 | pfam domains | PF08799 | 2 | 2 | 17054 | 2545 |
PRPF4,PRPF18 |
| 2.226e-02 | -3.80 | BAF250_C | pfam domains | PF12031 | 2 | 2 | 17054 | 2545 |
ARID1A,ARID1B |
| 2.226e-02 | -3.80 | Aph-1 | pfam domains | PF06105 | 2 | 2 | 17054 | 2545 |
APH1A,APH1B |
| 2.226e-02 | -3.80 | Cdc6_C | pfam domains | PF09079 | 2 | 2 | 17054 | 2545 |
CDC6,ORC1 |
| 2.226e-02 | -3.80 | FAM76 | pfam domains | PF16046 | 2 | 2 | 17054 | 2545 |
FAM76B,FAM76A |
| 2.226e-02 | -3.80 | PP1_bind | pfam domains | PF15276 | 2 | 2 | 17054 | 2545 |
CDCA2,MKI67 |
| 2.226e-02 | -3.80 | YIF1 | pfam domains | PF03878 | 2 | 2 | 17054 | 2545 |
YIF1A,YIF1B |
| 2.226e-02 | -3.80 | XTBD | pfam domains | PF11952 | 2 | 2 | 17054 | 2545 |
CDKN2AIP,CDKN2AIPNL |
| 2.226e-02 | -3.80 | Bap31 | pfam domains | PF05529 | 2 | 2 | 17054 | 2545 |
BCAP29,BCAP31 |
| 2.226e-02 | -3.80 | AXIN1_TNKS_BD | pfam domains | PF16646 | 2 | 2 | 17054 | 2545 |
AXIN1,AXIN2 |
| 2.226e-02 | -3.80 | EF_assoc_2 | pfam domains | PF08356 | 2 | 2 | 17054 | 2545 |
RHOT1,RHOT2 |
| 2.226e-02 | -3.80 | SQS_PSY | pfam domains | PF00494 | 2 | 2 | 17054 | 2545 |
NDUFAF6,FDFT1 |
| 2.226e-02 | -3.80 | DUF737 | pfam domains | PF05300 | 2 | 2 | 17054 | 2545 |
CHCHD3,CHCHD6 |
| 2.226e-02 | -3.80 | GRASP55_65 | pfam domains | PF04495 | 2 | 2 | 17054 | 2545 |
GORASP2,GORASP1 |
| 2.226e-02 | -3.80 | Rb_C | pfam domains | PF08934 | 2 | 2 | 17054 | 2545 |
RB1,RBL1 |
| 2.226e-02 | -3.80 | SOCS | pfam domains | PF12610 | 2 | 2 | 17054 | 2545 |
SOCS4,SOCS5 |
| 2.226e-02 | -3.80 | Flavodoxin_2 | pfam domains | PF02525 | 2 | 2 | 17054 | 2545 |
NQO1,NQO2 |
| 2.226e-02 | -3.80 | PITH | pfam domains | PF06201 | 2 | 2 | 17054 | 2545 |
TXNL1,PITHD1 |
| 2.226e-02 | -3.80 | Axin_b-cat_bind | pfam domains | PF08833 | 2 | 2 | 17054 | 2545 |
AXIN1,AXIN2 |
| 2.226e-02 | -3.80 | Ufd2P_core | pfam domains | PF10408 | 2 | 2 | 17054 | 2545 |
UBE4B,UBE4A |
| 2.226e-02 | -3.80 | Rtt106 | pfam domains | PF08512 | 2 | 2 | 17054 | 2545 |
SUPT16H,SSRP1 |
| 2.226e-02 | -3.80 | TRF | pfam domains | PF08558 | 2 | 2 | 17054 | 2545 |
TERF1,TERF2 |
| 2.226e-02 | -3.80 | PC_rep | pfam domains | PF01851 | 2 | 2 | 17054 | 2545 |
PSMD2,PSMD1 |
| 2.226e-02 | -3.80 | EF_assoc_1 | pfam domains | PF08355 | 2 | 2 | 17054 | 2545 |
RHOT1,RHOT2 |
| 2.226e-02 | -3.80 | CoA_binding | pfam domains | PF02629 | 2 | 2 | 17054 | 2545 |
SUCLG1,ACLY |
| 2.226e-02 | -3.80 | Ribosomal_L2 | pfam domains | PF00181 | 2 | 2 | 17054 | 2545 |
MRPL2,RPL8 |
| 2.226e-02 | -3.80 | Ribosomal_S2 | pfam domains | PF00318 | 2 | 2 | 17054 | 2545 |
MRPS2,RPSA |
| 2.226e-02 | -3.80 | GTSE1_N | pfam domains | PF15259 | 2 | 2 | 17054 | 2545 |
GTSE1,PSRC1 |
| 2.226e-02 | -3.80 | TAF | pfam domains | PF02969 | 2 | 2 | 17054 | 2545 |
TAF6L,TAF6 |
| 2.226e-02 | -3.80 | FOP_dimer | pfam domains | PF09398 | 2 | 2 | 17054 | 2545 |
FGFR1OP,FOPNL |
| 2.226e-02 | -3.80 | FragX_IP | pfam domains | PF05994 | 2 | 2 | 17054 | 2545 |
CYFIP1,CYFIP2 |
| 2.226e-02 | -3.80 | MOZART2 | pfam domains | PF12926 | 2 | 2 | 17054 | 2545 |
MZT2A,MZT2B |
| 2.226e-02 | -3.80 | Ribosomal_L2_C | pfam domains | PF03947 | 2 | 2 | 17054 | 2545 |
MRPL2,RPL8 |
| 2.226e-02 | -3.80 | Wyosine_form | pfam domains | PF08608 | 2 | 2 | 17054 | 2545 |
TYW1,TYW1B |
| 2.226e-02 | -3.80 | RNA_pol_Rpb4 | pfam domains | PF03874 | 2 | 2 | 17054 | 2545 |
CRCP,POLR2D |
| 2.226e-02 | -3.80 | eIF-5_eIF-2B | pfam domains | PF01873 | 2 | 2 | 17054 | 2545 |
EIF2S2,EIF5 |
| 2.228e-02 | -3.80 | PFDN1 (prefoldin subunit 1) | protein interactions | 5201 | 93 | 23 | 17029 | 2761 |
IMMT,PPP1R12A,HARS,HMGXB3,POC1A,NSUN2,EDRF1,RMI1,EXT2,GNB2,GEMIN5,PPP2CA,SEC31A,RFWD3,PFDN5,PFDN4,RPLP1,ACTB,ASNA1,PRPF4,IGBP1,DCAF5,DCTN1 |
| 2.230e-02 | -3.80 | interleukin-21-mediated signaling pathway | biological process | GO:0038114 | 8 | 4 | 17256 | 2622 |
JAK1,IL21R,STAT3,STAT1 |
| 2.230e-02 | -3.80 | response to interleukin-21 | biological process | GO:0098756 | 8 | 4 | 17256 | 2622 |
JAK1,IL21R,STAT3,STAT1 |
| 2.230e-02 | -3.80 | ribosome disassembly | biological process | GO:0032790 | 8 | 4 | 17256 | 2622 |
GFM2,PELO,EIF2D,MCTS1 |
| 2.230e-02 | -3.80 | spermidine metabolic process | biological process | GO:0008216 | 8 | 4 | 17256 | 2622 |
SRM,DHPS,SAT2,AMD1 |
| 2.230e-02 | -3.80 | plus-end-directed organelle transport along microtubule | biological process | GO:0072386 | 8 | 4 | 17256 | 2622 |
KIF5B,KIF23,KIFAP3,KIF3B |
| 2.230e-02 | -3.80 | regulation of maintenance of sister chromatid cohesion | biological process | GO:0034091 | 8 | 4 | 17256 | 2622 |
H2AFY,SLF1,NSMCE2,SLF2 |
| 2.230e-02 | -3.80 | DNA methylation involved in embryo development | biological process | GO:0043045 | 8 | 4 | 17256 | 2622 |
TET3,DNMT3A,TRIM28,DNMT1 |
| 2.230e-02 | -3.80 | positive regulation of mitophagy in response to mitochondrial depolarization | biological process | GO:0098779 | 8 | 4 | 17256 | 2622 |
SMURF1,OPTN,CDC37,MFN2 |
| 2.230e-02 | -3.80 | response to hydroxyurea | biological process | GO:0072710 | 8 | 4 | 17256 | 2622 |
TIMELESS,BLM,KAT7,SPIDR |
| 2.230e-02 | -3.80 | positive regulation of mitophagy | biological process | GO:1901526 | 8 | 4 | 17256 | 2622 |
SMURF1,OPTN,MFN2,CDC37 |
| 2.230e-02 | -3.80 | cellular response to interleukin-21 | biological process | GO:0098757 | 8 | 4 | 17256 | 2622 |
JAK1,IL21R,STAT3,STAT1 |
| 2.230e-02 | -3.80 | positive regulation of non-motile cilium assembly | biological process | GO:1902857 | 8 | 4 | 17256 | 2622 |
SEPT9,SEPT7,CENPJ,ATMIN |
| 2.230e-02 | -3.80 | response to cisplatin | biological process | GO:0072718 | 8 | 4 | 17256 | 2622 |
TIMELESS,KDM3B,SLC31A1,NUCB1 |
| 2.230e-02 | -3.80 | meiotic DNA recombinase assembly | biological process | GO:0000707 | 8 | 4 | 17256 | 2622 |
RAD51C,XRCC3,RAD51D,XRCC2 |
| 2.230e-02 | -3.80 | regulation of maintenance of mitotic sister chromatid cohesion | biological process | GO:0034182 | 8 | 4 | 17256 | 2622 |
H2AFY,SLF1,NSMCE2,SLF2 |
| 2.230e-02 | -3.80 | formation of translation preinitiation complex | biological process | GO:0001731 | 8 | 4 | 17256 | 2622 |
EIF5,EIF4H,EIF2D,MCTS1 |
| 2.230e-02 | -3.80 | changes to DNA methylation involved in embryo development | biological process | GO:1901538 | 8 | 4 | 17256 | 2622 |
TET3,DNMT3A,TRIM28,DNMT1 |
| 2.234e-02 | -3.80 | GOTZMANN_EPITHELIAL_TO_MESENCHYMAL_TRANSITION_UP | MSigDB lists | GOTZMANN_EPITHELIAL_TO_MESENCHYMAL_TRANSITION_UP | 68 | 17 | 17377 | 2626 |
MKI67,BRCA1,OAT,ODC1,RPSA,RBL1,TPP2,DCK,GADD45B,MAP4,GLG1,ITGB1,LY75,CLU,SMAD1,S100A6,SMARCD1 |
| 2.240e-02 | -3.80 | Phosphofurin_acidic_CS-1 | interpro domains | IPR019381 | 2 | 2 | 18492 | 2768 |
PACS1,PACS2 |
| 2.240e-02 | -3.80 | BAF250_C | interpro domains | IPR033388 | 2 | 2 | 18492 | 2768 |
ARID1A,ARID1B |
| 2.240e-02 | -3.80 | PRP4-like | interpro domains | IPR014906 | 2 | 2 | 18492 | 2768 |
PRPF4,PRPF18 |
| 2.240e-02 | -3.80 | Ribosomal_S2 | interpro domains | IPR001865 | 2 | 2 | 18492 | 2768 |
MRPS2,RPSA |
| 2.240e-02 | -3.80 | Proteasome/cyclosome_rpt | interpro domains | IPR002015 | 2 | 2 | 18492 | 2768 |
PSMD2,PSMD1 |
| 2.240e-02 | -3.80 | DNA-dir_RNA_pol_M/15kDasu | interpro domains | IPR001529 | 2 | 2 | 18492 | 2768 |
POLR2I,POLR3K |
| 2.240e-02 | -3.80 | Citrate_synth-like_sm_a-sub | interpro domains | IPR016143 | 2 | 2 | 18492 | 2768 |
CS,ACLY |
| 2.240e-02 | -3.80 | SAP30_Sin3-bd | interpro domains | IPR025718 | 2 | 2 | 18492 | 2768 |
SAP30L,SAP30 |
| 2.240e-02 | -3.80 | RNA_pol_II_Rpb4_core | interpro domains | IPR006590 | 2 | 2 | 18492 | 2768 |
CRCP,POLR2D |
| 2.240e-02 | -3.80 | Pyrophosphatase_sf | interpro domains | IPR036649 | 2 | 2 | 18492 | 2768 |
PPA1,PPA2 |
| 2.240e-02 | -3.80 | PITH_dom | interpro domains | IPR010400 | 2 | 2 | 18492 | 2768 |
TXNL1,PITHD1 |
| 2.240e-02 | -3.80 | CoA-bd | interpro domains | IPR003781 | 2 | 2 | 18492 | 2768 |
SUCLG1,ACLY |
| 2.240e-02 | -3.80 | TAF6_C | interpro domains | IPR011442 | 2 | 2 | 18492 | 2768 |
TAF6L,TAF6 |
| 2.240e-02 | -3.80 | Coatomer_WD-assoc_reg | interpro domains | IPR006692 | 2 | 2 | 18492 | 2768 |
COPA,COPB2 |
| 2.240e-02 | -3.80 | RBM3/CIRBP_RRM | interpro domains | IPR034278 | 2 | 2 | 18492 | 2768 |
RBM3,CIRBP |
| 2.240e-02 | -3.80 | Telomere_rpt-bd_fac_dimer_dom | interpro domains | IPR013867 | 2 | 2 | 18492 | 2768 |
TERF1,TERF2 |
| 2.240e-02 | -3.80 | Cyt_c-like_dom_sf | interpro domains | IPR036909 | 2 | 2 | 18492 | 2768 |
CYCS,CYC1 |
| 2.240e-02 | -3.80 | GTSE1_N | interpro domains | IPR032768 | 2 | 2 | 18492 | 2768 |
GTSE1,PSRC1 |
| 2.240e-02 | -3.80 | BAF250/Osa | interpro domains | IPR021906 | 2 | 2 | 18492 | 2768 |
ARID1A,ARID1B |
| 2.240e-02 | -3.80 | Transl_init_fac_IF2/IF5_Zn-bd | interpro domains | IPR016190 | 2 | 2 | 18492 | 2768 |
EIF2S2,EIF5 |
| 2.240e-02 | -3.80 | EF_hand_assoc_1 | interpro domains | IPR013566 | 2 | 2 | 18492 | 2768 |
RHOT1,RHOT2 |
| 2.240e-02 | -3.80 | PRP4-like_sf | interpro domains | IPR036285 | 2 | 2 | 18492 | 2768 |
PRPF4,PRPF18 |
| 2.240e-02 | -3.80 | HEX_eukaryotic_N | interpro domains | IPR029019 | 2 | 2 | 18492 | 2768 |
HEXA,HEXB |
| 2.240e-02 | -3.80 | TERF1/2 | interpro domains | IPR017357 | 2 | 2 | 18492 | 2768 |
TERF1,TERF2 |
| 2.240e-02 | -3.80 | FAM76 | interpro domains | IPR032017 | 2 | 2 | 18492 | 2768 |
FAM76B,FAM76A |
| 2.240e-02 | -3.80 | Ribosomal_L25/Gln-tRNA_synth | interpro domains | IPR011035 | 2 | 2 | 18492 | 2768 |
EPRS,QARS |
| 2.240e-02 | -3.80 | Flavodoxin_fold | interpro domains | IPR003680 | 2 | 2 | 18492 | 2768 |
NQO1,NQO2 |
| 2.240e-02 | -3.80 | MYSc_Myo9 | interpro domains | IPR036023 | 2 | 2 | 18492 | 2768 |
MYO9B,MYO9A |
| 2.240e-02 | -3.80 | Ribosomal_L12 | interpro domains | IPR027534 | 2 | 2 | 18492 | 2768 |
RPLP2,RPLP1 |
| 2.240e-02 | -3.80 | AGP_acyltrans | interpro domains | IPR004552 | 2 | 2 | 18492 | 2768 |
AGPAT2,AGPAT1 |
| 2.240e-02 | -3.80 | Ub_conjug_fac_E4_core | interpro domains | IPR019474 | 2 | 2 | 18492 | 2768 |
UBE4B,UBE4A |
| 2.240e-02 | -3.80 | Citrt_syn/SCS-alpha_CS | interpro domains | IPR033847 | 2 | 2 | 18492 | 2768 |
SUCLG1,ACLY |
| 2.240e-02 | -3.80 | XPA_sf | interpro domains | IPR037129 | 2 | 2 | 18492 | 2768 |
SLC30A9,XPA |
| 2.240e-02 | -3.80 | XPC-bd_sf | interpro domains | IPR036353 | 2 | 2 | 18492 | 2768 |
RAD23B,RAD23A |
| 2.240e-02 | -3.80 | PSP_pro-rich | interpro domains | IPR006568 | 2 | 2 | 18492 | 2768 |
ZCCHC8,SF3B2 |
| 2.240e-02 | -3.80 | RRM1_SRSF4-like | interpro domains | IPR035585 | 2 | 2 | 18492 | 2768 |
SRSF5,SRSF4 |
| 2.240e-02 | -3.80 | BAP29/BAP31 | interpro domains | IPR008417 | 2 | 2 | 18492 | 2768 |
BCAP29,BCAP31 |
| 2.240e-02 | -3.80 | Ribosomal_L2 | interpro domains | IPR002171 | 2 | 2 | 18492 | 2768 |
MRPL2,RPL8 |
| 2.240e-02 | -3.80 | Telomere_rpt-bd_fac_dimer_sf | interpro domains | IPR036507 | 2 | 2 | 18492 | 2768 |
TERF1,TERF2 |
| 2.240e-02 | -3.80 | GRASP55_65 | interpro domains | IPR007583 | 2 | 2 | 18492 | 2768 |
GORASP2,GORASP1 |
| 2.240e-02 | -3.80 | Pyrophosphatase | interpro domains | IPR008162 | 2 | 2 | 18492 | 2768 |
PPA1,PPA2 |
| 2.240e-02 | -3.80 | SAP30_zn-finger | interpro domains | IPR025717 | 2 | 2 | 18492 | 2768 |
SAP30L,SAP30 |
| 2.240e-02 | -3.80 | Galactokinase | interpro domains | IPR000705 | 2 | 2 | 18492 | 2768 |
GALK1,GALK2 |
| 2.240e-02 | -3.80 | Ile-tRNA-ligase | interpro domains | IPR002301 | 2 | 2 | 18492 | 2768 |
IARS,IARS2 |
| 2.240e-02 | -3.80 | P1/P2_N_sf | interpro domains | IPR038716 | 2 | 2 | 18492 | 2768 |
RPLP2,RPLP1 |
| 2.240e-02 | -3.80 | Transl_init_fac_IF2/IF5_N | interpro domains | IPR016189 | 2 | 2 | 18492 | 2768 |
EIF2S2,EIF5 |
| 2.240e-02 | -3.80 | Miro | interpro domains | IPR021181 | 2 | 2 | 18492 | 2768 |
RHOT1,RHOT2 |
| 2.240e-02 | -3.80 | Yif1_fam | interpro domains | IPR005578 | 2 | 2 | 18492 | 2768 |
YIF1A,YIF1B |
| 2.240e-02 | -3.80 | Cytoplasmic_FMR1-int | interpro domains | IPR008081 | 2 | 2 | 18492 | 2768 |
CYFIP1,CYFIP2 |
| 2.240e-02 | -3.80 | ADAM10_ADAM17 | interpro domains | IPR034025 | 2 | 2 | 18492 | 2768 |
ADAM17,ADAM10 |
| 2.240e-02 | -3.80 | Axin_TNKS-bd | interpro domains | IPR032101 | 2 | 2 | 18492 | 2768 |
AXIN1,AXIN2 |
| 2.240e-02 | -3.80 | Cit_synth/succinyl-CoA_lig_AS | interpro domains | IPR017440 | 2 | 2 | 18492 | 2768 |
SUCLG1,ACLY |
| 2.240e-02 | -3.80 | DUF1747 | interpro domains | IPR013719 | 2 | 2 | 18492 | 2768 |
SUPT16H,SSRP1 |
| 2.240e-02 | -3.80 | Citrate_synth-like_lrg_a-sub | interpro domains | IPR016142 | 2 | 2 | 18492 | 2768 |
CS,ACLY |
| 2.240e-02 | -3.80 | DNase_TatD-rel_CS | interpro domains | IPR018228 | 2 | 2 | 18492 | 2768 |
TATDN1,TATDN2 |
| 2.240e-02 | -3.80 | Cobalamin-bd_sf | interpro domains | IPR036724 | 2 | 2 | 18492 | 2768 |
MUT,MTR |
| 2.240e-02 | -3.80 | Ribosomal_S2_CS | interpro domains | IPR018130 | 2 | 2 | 18492 | 2768 |
MRPS2,RPSA |
| 2.240e-02 | -3.80 | Znf_DNA_glyclase/AP_lyase | interpro domains | IPR000214 | 2 | 2 | 18492 | 2768 |
NEIL3,NEIL2 |
| 2.240e-02 | -3.80 | SIKE | interpro domains | IPR008555 | 2 | 2 | 18492 | 2768 |
SIKE1,FGFR1OP2 |
| 2.240e-02 | -3.80 | GalKase_gal-bd | interpro domains | IPR019539 | 2 | 2 | 18492 | 2768 |
GALK1,GALK2 |
| 2.240e-02 | -3.80 | Cobalamin-bd | interpro domains | IPR006158 | 2 | 2 | 18492 | 2768 |
MUT,MTR |
| 2.240e-02 | -3.80 | MOZART2 | interpro domains | IPR024332 | 2 | 2 | 18492 | 2768 |
MZT2A,MZT2B |
| 2.240e-02 | -3.80 | SOCS4/SOCS5_dom | interpro domains | IPR022252 | 2 | 2 | 18492 | 2768 |
SOCS5,SOCS4 |
| 2.240e-02 | -3.80 | Rad23 | interpro domains | IPR004806 | 2 | 2 | 18492 | 2768 |
RAD23B,RAD23A |
| 2.240e-02 | -3.80 | XPC-bd | interpro domains | IPR015360 | 2 | 2 | 18492 | 2768 |
RAD23B,RAD23A |
| 2.240e-02 | -3.80 | Transl_init_fac_IF2/IF5 | interpro domains | IPR002735 | 2 | 2 | 18492 | 2768 |
EIF2S2,EIF5 |
| 2.240e-02 | -3.80 | Squ/phyt_synthse | interpro domains | IPR002060 | 2 | 2 | 18492 | 2768 |
NDUFAF6,FDFT1 |
| 2.240e-02 | -3.80 | TAF6 | interpro domains | IPR037796 | 2 | 2 | 18492 | 2768 |
TAF6L,TAF6 |
| 2.240e-02 | -3.80 | Ribosomal_L2_C | interpro domains | IPR022669 | 2 | 2 | 18492 | 2768 |
MRPL2,RPL8 |
| 2.240e-02 | -3.80 | MIC19/MIC25 | interpro domains | IPR007964 | 2 | 2 | 18492 | 2768 |
CHCHD3,CHCHD6 |
| 2.240e-02 | -3.80 | EF_hand_assoc_2 | interpro domains | IPR013567 | 2 | 2 | 18492 | 2768 |
RHOT1,RHOT2 |
| 2.240e-02 | -3.80 | Axin_b-cat-bd | interpro domains | IPR014936 | 2 | 2 | 18492 | 2768 |
AXIN1,AXIN2 |
| 2.240e-02 | -3.80 | SUMF_dom | interpro domains | IPR005532 | 2 | 2 | 18492 | 2768 |
SUMF2,SUMF1 |
| 2.240e-02 | -3.80 | Beta_hexosaminidase_sua/sub | interpro domains | IPR025705 | 2 | 2 | 18492 | 2768 |
HEXA,HEXB |
| 2.240e-02 | -3.80 | Citrate_synthase_sf | interpro domains | IPR036969 | 2 | 2 | 18492 | 2768 |
CS,ACLY |
| 2.240e-02 | -3.80 | SAP30_C_sf | interpro domains | IPR038291 | 2 | 2 | 18492 | 2768 |
SAP30L,SAP30 |
| 2.240e-02 | -3.80 | XTBD_dom_prot | interpro domains | IPR037526 | 2 | 2 | 18492 | 2768 |
CDKN2AIP,CDKN2AIPNL |
| 2.240e-02 | -3.80 | RNA_pol_II_repeat_euk | interpro domains | IPR000684 | 2 | 2 | 18492 | 2768 |
ZNF768,POLR2A |
| 2.240e-02 | -3.80 | RNA_pol_II_Rpb4 | interpro domains | IPR005574 | 2 | 2 | 18492 | 2768 |
CRCP,POLR2D |
| 2.240e-02 | -3.80 | DUF3512 | interpro domains | IPR021900 | 2 | 2 | 18492 | 2768 |
BRD7,BRD9 |
| 2.240e-02 | -3.80 | GRASP55/65_PDZ | interpro domains | IPR024958 | 2 | 2 | 18492 | 2768 |
GORASP2,GORASP1 |
| 2.240e-02 | -3.80 | Rbsml_prot_L2_RNA-bd_dom | interpro domains | IPR022666 | 2 | 2 | 18492 | 2768 |
MRPL2,RPL8 |
| 2.240e-02 | -3.80 | tRNA_wybutosine-synth | interpro domains | IPR013917 | 2 | 2 | 18492 | 2768 |
TYW1,TYW1B |
| 2.240e-02 | -3.80 | XTBD | interpro domains | IPR021859 | 2 | 2 | 18492 | 2768 |
CDKN2AIP,CDKN2AIPNL |
| 2.240e-02 | -3.80 | PDCD2_C | interpro domains | IPR007320 | 2 | 2 | 18492 | 2768 |
PDCD2,PDCD2L |
| 2.240e-02 | -3.80 | Rbsml_L25/Gln-tRNA_synth_N | interpro domains | IPR020056 | 2 | 2 | 18492 | 2768 |
EPRS,QARS |
| 2.240e-02 | -3.80 | FOP_dimerisation-dom_N | interpro domains | IPR018993 | 2 | 2 | 18492 | 2768 |
FGFR1OP,FOPNL |
| 2.240e-02 | -3.80 | Cdc6_C | interpro domains | IPR015163 | 2 | 2 | 18492 | 2768 |
CDC6,ORC1 |
| 2.240e-02 | -3.80 | Lamina-ass_polypeptide_CLAP1C | interpro domains | IPR008662 | 2 | 2 | 18492 | 2768 |
TOR1AIP2,TOR1AIP1 |
| 2.240e-02 | -3.80 | Mevalonate/galactokinase | interpro domains | IPR006206 | 2 | 2 | 18492 | 2768 |
GALK1,GALK2 |
| 2.240e-02 | -3.80 | MAPK_ERK1/2 | interpro domains | IPR008349 | 2 | 2 | 18492 | 2768 |
MAPK1,MAPK3 |
| 2.240e-02 | -3.80 | Galactokinase_CS | interpro domains | IPR019741 | 2 | 2 | 18492 | 2768 |
GALK1,GALK2 |
| 2.240e-02 | -3.80 | tRNA_wybutosine-synthase | interpro domains | IPR034556 | 2 | 2 | 18492 | 2768 |
TYW1,TYW1B |
| 2.240e-02 | -3.80 | FUBP_C | interpro domains | IPR015096 | 2 | 2 | 18492 | 2768 |
KHSRP,FUBP1 |
| 2.240e-02 | -3.80 | Clathrin_b-adaptin_app_Ig-like | interpro domains | IPR013037 | 2 | 2 | 18492 | 2768 |
AP2B1,AP1B1 |
| 2.240e-02 | -3.80 | MIRO_dom | interpro domains | IPR020860 | 2 | 2 | 18492 | 2768 |
RHOT1,RHOT2 |
| 2.240e-02 | -3.80 | Ribosomal_S2_flav_dom_sf | interpro domains | IPR023591 | 2 | 2 | 18492 | 2768 |
MRPS2,RPSA |
| 2.240e-02 | -3.80 | PITH_dom_sf | interpro domains | IPR037047 | 2 | 2 | 18492 | 2768 |
TXNL1,PITHD1 |
| 2.240e-02 | -3.80 | Rpb4/RPC9_sf | interpro domains | IPR038324 | 2 | 2 | 18492 | 2768 |
CRCP,POLR2D |
| 2.240e-02 | -3.80 | PP1-bd | interpro domains | IPR029334 | 2 | 2 | 18492 | 2768 |
CDCA2,MKI67 |
| 2.240e-02 | -3.80 | Glu/Gln-tRNA-synth_Ib_codon-bd | interpro domains | IPR020059 | 2 | 2 | 18492 | 2768 |
EPRS,QARS |
| 2.240e-02 | -3.80 | Transform_prot_C-ets | interpro domains | IPR016311 | 2 | 2 | 18492 | 2768 |
ETS2,ETS1 |
| 2.240e-02 | -3.80 | His_deAcase_SAP30/SAP30L | interpro domains | IPR024145 | 2 | 2 | 18492 | 2768 |
SAP30L,SAP30 |
| 2.240e-02 | -3.80 | Sec2_N | interpro domains | IPR009449 | 2 | 2 | 18492 | 2768 |
RAB3IP,RAB3IL1 |
| 2.240e-02 | -3.80 | Metaxin | interpro domains | IPR017410 | 2 | 2 | 18492 | 2768 |
MTX1,MTX3 |
| 2.240e-02 | -3.80 | Ubiquitinyl_hydrolase | interpro domains | IPR016652 | 2 | 2 | 18492 | 2768 |
USP5,USP13 |
| 2.240e-02 | -3.80 | ATPase_proteolipid_csu | interpro domains | IPR000245 | 2 | 2 | 18492 | 2768 |
ATP6V0B,ATP6V0C |
| 2.240e-02 | -3.80 | DDA3/GTSE-1 | interpro domains | IPR026657 | 2 | 2 | 18492 | 2768 |
GTSE1,PSRC1 |
| 2.240e-02 | -3.80 | LAP1C-like_C_sf | interpro domains | IPR038599 | 2 | 2 | 18492 | 2768 |
TOR1AIP2,TOR1AIP1 |
| 2.240e-02 | -3.80 | Citrate_synthase | interpro domains | IPR002020 | 2 | 2 | 18492 | 2768 |
CS,ACLY |
| 2.240e-02 | -3.80 | Malate_DH_AS | interpro domains | IPR001252 | 2 | 2 | 18492 | 2768 |
MDH1,MDH2 |
| 2.240e-02 | -3.80 | Aph-1 | interpro domains | IPR009294 | 2 | 2 | 18492 | 2768 |
APH1A,APH1B |
| 2.240e-02 | -3.80 | GMF | interpro domains | IPR011171 | 2 | 2 | 18492 | 2768 |
GMFG,GMFB |
| 2.240e-02 | -3.80 | CABLES1/2 | interpro domains | IPR012388 | 2 | 2 | 18492 | 2768 |
CABLES2,CABLES1 |
| 2.240e-02 | -3.80 | Bcl2/BclX | interpro domains | IPR004725 | 2 | 2 | 18492 | 2768 |
BCL2,BCL2L1 |
| 2.240e-02 | -3.80 | ABC_Tap-like | interpro domains | IPR013305 | 2 | 2 | 18492 | 2768 |
TAP2,TAP1 |
| 2.243e-02 | -3.80 | BCAT_BILD_ET_AL_DN | MSigDB lists | BCAT_BILD_ET_AL_DN | 43 | 12 | 17377 | 2626 |
ANKRD28,GCLM,PRPF38B,ASH1L,RAP1A,SHC1,TNFAIP3,PRKDC,H2AFY,SECISBP2,ZSWIM6,SRSF1 |
| 2.243e-02 | -3.80 | KYNG_RESPONSE_TO_H2O2_VIA_ERCC6_DN | MSigDB lists | KYNG_RESPONSE_TO_H2O2_VIA_ERCC6_DN | 43 | 12 | 17377 | 2626 |
NAP1L1,CTSS,TCF3,BDH1,OAZ2,SIAH2,DNAJB1,PM20D2,PLXNA1,ALDH18A1,DDB1,ELOF1 |
| 2.243e-02 | -3.80 | GO_CYTOSOLIC_SMALL_RIBOSOMAL_SUBUNIT | MSigDB lists | GO_CYTOSOLIC_SMALL_RIBOSOMAL_SUBUNIT | 43 | 12 | 17377 | 2626 |
RPS15,RPS2,RPS27A,RPS14,EIF2D,RPS10,RPS24,FAU,RPS26,RPS9,RPSA,MCTS1 |
| 2.243e-02 | -3.80 | GALLUZZI_PERMEABILIZE_MITOCHONDRIA | MSigDB lists | GALLUZZI_PERMEABILIZE_MITOCHONDRIA | 43 | 12 | 17377 | 2626 |
MOAP1,BAK1,CLIC4,SHC1,SIVA1,VDAC2,MCL1,BCL2,STK11,BCL2L1,VDAC1,SH3GLB1 |
| 2.243e-02 | -3.80 | PID_TCPTP_PATHWAY | MSigDB lists | PID_TCPTP_PATHWAY | 43 | 12 | 17377 | 2626 |
PTPN2,SHC1,JAK1,STAT6,PIK3R2,RAB4A,STAT1,ITGB1,KPNA2,EIF2A,LMAN1,STAT3 |
| 2.243e-02 | -3.80 | ULE_SPLICING_VIA_NOVA2 | MSigDB lists | ULE_SPLICING_VIA_NOVA2 | 43 | 12 | 17377 | 2626 |
PTPRF,APLP2,GOLGA4,AGRN,MAP4K4,ANK3,CADM1,IDH3B,NCDN,CAMK2G,EPB41,SPTAN1 |
| 2.243e-02 | -3.80 | PID_CXCR3_PATHWAY | MSigDB lists | PID_CXCR3_PATHWAY | 43 | 12 | 17377 | 2626 |
PDPK1,NRAS,RAF1,PIK3R2,KRAS,MAPK14,MAPK1,GNAI2,MAP2K2,HRAS,MAPK3,MLST8 |
| 2.245e-02 | -3.80 | establishment of protein localization to plasma membrane | biological process | GO:0061951 | 38 | 11 | 17256 | 2622 |
GCC2,GOLGA4,GOLPH3L,SYS1,GOLGA7,NSF,GRIPAP1,ANK3,MACF1,RAB11A,OPTN |
| 2.245e-02 | -3.80 | positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway | biological process | GO:1901030 | 38 | 11 | 17256 | 2622 |
BAK1,ATP5IF1,DYNLL1,TFDP1,E2F1,PPP3R1,BCL2,YWHAZ,TP53BP2,TFDP2,YWHAH |
| 2.245e-02 | -3.80 | GO_POSITIVE_REGULATION_OF_SEQUENCE_SPECIFIC_DNA_BINDING_TRANSCRIPTION_FACTOR_ACTIVITY | MSigDB lists | GO_POSITIVE_REGULATION_OF_SEQUENCE_SPECIFIC_DNA_BINDING_TRANSCRIPTION_FACTOR_ACTIVITY | 222 | 45 | 17377 | 2626 |
DDX58,PHB2,TCF3,CIB1,SMARCA4,PARK7,JMY,CFLAR,DDRGK1,TERF2IP,PSMA6,SP100,PTEN,BUD31,ARHGEF2,MAVS,ATF2,MTPN,TRIM14,DVL2,TGFB1,PPP3CA,TRIM8,TRAPPC9,RNF25,UBE2V1,LRP5,KRAS,ERC1,HSPA1B,CAT,TRIM26,TAB2,PRDX3,RPS27A,HIPK2,CEBPG,TICAM1,TRIM32,CLU,TAF12,TRIM52,TRAF5,LRP8,RHEBL1 |
| 2.245e-02 | -3.80 | V$AP2ALPHA_01 | MSigDB lists | V$AP2ALPHA_01 | 222 | 45 | 17377 | 2626 |
POU3F2,PLXNC1,TRERF1,FAM129A,FAM76A,CIB1,KLF13,CTCF,MXD4,PABPC4,FBRS,PHC2,TFAP4,APLP2,NFATC3,MLX,KDM2A,ZNRF2,ZNF335,PPP1R12C,STAT3,UBE2M,PABPC1,LUC7L2,PDLIM2,RBM15B,KDM3B,SP3,KLF10,ERF,CIC,LDB1,MFNG,E2F3,ARID1A,MAP2K2,EIF3A,RXRB,UBTF,TMEM127,ATP6V1D,AHNAK,MAP4,NUP62,LRP8 |
| 2.245e-02 | -3.80 | OSWALD_HEMATOPOIETIC_STEM_CELL_IN_COLLAGEN_GEL_UP | MSigDB lists | OSWALD_HEMATOPOIETIC_STEM_CELL_IN_COLLAGEN_GEL_UP | 222 | 45 | 17377 | 2626 |
IER2,MAGEH1,PKP4,ADD1,RPLP2,NF1,SF3B1,RGS2,RGS1,CFLAR,EBP,DNAJC8,SMC3,CTNNBL1,PHF14,AHCYL1,SLC12A2,TIPARP,EEF1D,EIF5A,RHOBTB3,BRD4,BIRC3,KAT2A,TNFAIP3,DHX29,BTG2,CIRBP,SEPT8,MCL1,RPL27A,ARMC8,KLF6,MAPK3,SEC23IP,GALNT2,ETS2,CHD3,LUC7L3,TIMM17A,GADD45B,ODF2,H3F3A,ATP6V0E1,ADNP2 |
| 2.249e-02 | -3.79 | ceramide metabolic process | biological process | GO:0006672 | 78 | 19 | 17256 | 2622 |
GALC,HEXB,CERK,GBA,ASAH1,NEU1,PPP2CA,ORMDL2,ITGB8,CERS6,SAMD8,SMPD4,ST8SIA2,SPTSSA,B4GALT3,CLN3,CLN6,GM2A,HTRA2 |
| 2.249e-02 | -3.79 | tRNA modification | biological process | GO:0006400 | 78 | 19 | 17256 | 2622 |
SEPHS2,CTU2,METTL1,TRMT6,NSUN2,METTL2A,ELP4,GTPBP3,DUS4L,DUS3L,THADA,ELP5,TRMU,TYW5,WDR4,DUS2,FTSJ1,TRMT10B,OSGEPL1 |
| 2.250e-02 | -3.79 | Hh mutants that don't undergo autocatalytic processing are degraded by ERAD | REACTOME pathways | R-HSA-5362768 | 58 | 16 | 10287 | 1696 |
PSMA8,PSMB7,PSMA1,SYVN1,PSMB9,PSMD9,PSMB3,PSMC4,PSMD2,PSMA6,PSMD1,RPS27A,PSMD3,PSMD8,SEL1L,PSMC1 |
| 2.250e-02 | -3.79 | GSE5542_UNTREATED_VS_IFNA_TREATED_EPITHELIAL_CELLS_6H_DN | MSigDB lists | GSE5542_UNTREATED_VS_IFNA_TREATED_EPITHELIAL_CELLS_6H_DN | 171 | 36 | 17377 | 2626 |
PIGM,SUMF1,GLUD1,RAPGEF6,APP,PCYOX1L,C1GALT1,CLUAP1,PRKD3,SUCLG2,CREB1,TOP1MT,SGCB,ZNF770,PTPRK,PGAP2,TTPAL,ARHGAP17,TIMP2,ZNF84,KIAA0040,KCNQ1,ZP3,STK17B,SPPL2B,CLNS1A,ANKRD46,RAD54B,SERTAD2,EIF2D,GAS2,OSGEPL1,LTA4H,CHMP7,USP53,ZC3HC1 |
| 2.252e-02 | -3.79 | ubiquitin-like protein-specific protease activity | molecular function | GO:0019783 | 130 | 29 | 17224 | 2647 |
USP7,OTUD5,CYLD,ATXN3,TNFAIP3,KAT2A,USP42,USP39,USP10,OTUD3,USP22,USP48,USP21,USP36,WDR48,USP5,ANKZF1,UCHL5,TANK,USP32,USP20,VCPIP1,JOSD1,USP11,ZRANB1,USP53,SENP1,USP34,USP13 |
| 2.257e-02 | -3.79 | proton transmembrane transport | biological process | GO:1902600 | 126 | 28 | 17256 | 2622 |
COX15,COX5B,ATP6V0A1,NDUFA4,COX4I1,SLC25A22,ATP5F1B,SLC17A5,ATP5MF,ATP6V1B2,ATP5PF,NDUFS7,CYB5A,STOML2,ATP6V0B,ATP1A1,ATP5MC3,COX7A2L,COX8A,COX5A,ATP6V0A2,ATP6V0C,ATP5F1A,CYC1,ATP6V1C1,ATP6V0D1,ATP6V0E1,ATP6V1G1 |
| 2.258e-02 | -3.79 | active ion transmembrane transporter activity | molecular function | GO:0022853 | 67 | 17 | 17224 | 2647 |
ATP13A1,ATP2C1,ATP6V0A1,ATP5F1B,ATP6V1B2,ATP6V0B,ATP1A1,ATP2A2,ATP5MC3,ATP13A3,ATP6V0A2,ATP6V0C,ATP5F1A,ATP6V1C1,ATP6V0E1,ATP6V0D1,ATP6V1G1 |
| 2.258e-02 | -3.79 | ATPase coupled ion transmembrane transporter activity | molecular function | GO:0042625 | 67 | 17 | 17224 | 2647 |
ATP13A1,ATP2C1,ATP6V0A1,ATP5F1B,ATP6V1B2,ATP6V0B,ATP1A1,ATP2A2,ATP5MC3,ATP13A3,ATP6V0A2,ATP6V0C,ATP5F1A,ATP6V1C1,ATP6V0E1,ATP6V0D1,ATP6V1G1 |
| 2.264e-02 | -3.79 | normal | COSMIC cancer mutations | normal | 16 | 6 | 17385 | 2587 |
GNAS,FGFR3,KRAS,NRAS,HRAS,CDKN2A |
| 2.264e-02 | -3.79 | serrated_polyp | COSMIC cancer mutations | serrated_polyp | 16 | 6 | 17385 | 2587 |
GNAS,KRAS,STK11,NRAS,PTEN,SMAD4 |
| 2.264e-02 | -3.79 | large_intestine-colon-serrated_polyp-serrated_adenoma | COSMIC cancer mutations | large_intestine-colon-serrated_polyp-serrated_adenoma | 16 | 6 | 17385 | 2587 |
GNAS,KRAS,STK11,NRAS,PTEN,SMAD4 |
| 2.264e-02 | -3.79 | parietooccipital | COSMIC cancer mutations | parietooccipital | 16 | 6 | 17385 | 2587 |
CDKN2C,H3F3A,NF1,PTEN,MSH6,MSH2 |
| 2.264e-02 | -3.79 | embryonal_carcinoma | COSMIC cancer mutations | embryonal_carcinoma | 16 | 6 | 17385 | 2587 |
SMARCA4,KRAS,NRAS,SF3B1,HRAS,CDKN2A |
| 2.264e-02 | -3.79 | tubular | COSMIC cancer mutations | tubular | 16 | 6 | 17385 | 2587 |
GNAS,KRAS,STK11,NRAS,PTEN,SMAD4 |
| 2.264e-02 | -3.79 | serrated_adenoma | COSMIC cancer mutations | serrated_adenoma | 16 | 6 | 17385 | 2587 |
GNAS,KRAS,STK11,NRAS,PTEN,SMAD4 |
| 2.267e-02 | -3.79 | haematopoietic_and_lymphoid_tissue-skin-lymphoid_neoplasm-anaplastic_large_cell_lymphoma | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-skin-lymphoid_neoplasm-anaplastic_large_cell_lymphoma | 34 | 10 | 17385 | 2587 |
FGFR3,RB1,NRAS,PTEN,VHL,STK11,KRAS,STAT3,HRAS,CDKN2A |
| 2.268e-02 | -3.79 | oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor | molecular function | GO:0016676 | 24 | 8 | 17224 | 2647 |
COX5B,COX15,COX7A2L,COX8A,COX5A,COX4I1,NDUFA4,CYB5A |
| 2.268e-02 | -3.79 | cytochrome-c oxidase activity | molecular function | GO:0004129 | 24 | 8 | 17224 | 2647 |
COX5B,COX15,COX7A2L,COX8A,COX5A,COX4I1,NDUFA4,CYB5A |
| 2.268e-02 | -3.79 | heme-copper terminal oxidase activity | molecular function | GO:0015002 | 24 | 8 | 17224 | 2647 |
COX5B,COX15,COX7A2L,COX8A,COX5A,COX4I1,NDUFA4,CYB5A |
| 2.268e-02 | -3.79 | GO_POSITIVE_REGULATION_OF_CELLULAR_AMIDE_METABOLIC_PROCESS | MSigDB lists | GO_POSITIVE_REGULATION_OF_CELLULAR_AMIDE_METABOLIC_PROCESS | 105 | 24 | 17377 | 2626 |
TGFB1,EIF5A,NCOR2,POLR2G,NCK1,FAM129A,CIRBP,POLR2D,EIF2AK4,SOX4,METTL3,ABCF1,RPS9,PICALM,SERP1,PAIP1,MAPK3,SYNCRIP,EIF4A3,RBM3,CLU,MAPK1,PABPC1,NSUN4 |
| 2.268e-02 | -3.79 | GO_TRANSITION_METAL_ION_TRANSPORT | MSigDB lists | GO_TRANSITION_METAL_ION_TRANSPORT | 105 | 24 | 17377 | 2626 |
SLC30A9,SLC39A9,FTL,ATP13A1,RAB11B,ATP2C1,SLC39A13,ATP6V0A1,ZP3,ATP6V1B2,CUTC,PICALM,TFRC,SLC25A37,ATP6V0B,SLC31A1,ATP6V1D,DNM2,ATP6V0A2,ATP6V0C,ATP6V1C1,ATP6V0D1,ATP6V0E1,ATP6V1G1 |
| 2.268e-02 | -3.79 | GSE24142_EARLY_THYMIC_PROGENITOR_VS_DN3_THYMOCYTE_DN | MSigDB lists | GSE24142_EARLY_THYMIC_PROGENITOR_VS_DN3_THYMOCYTE_DN | 188 | 39 | 17377 | 2626 |
HIVEP3,TCF12,TRIM11,ENSA,SMARCA4,AGPAT3,ETS1,PITHD1,PRNP,MLX,PHTF1,DAPK1,TPST1,BCL2,CLTB,LDHB,ELOVL5,RHOA,PPT1,TSPYL4,PGS1,RAB3IP,MPG,TOLLIP,CYB5A,PTPRF,PLD3,HSPB11,ETS2,CLK3,TULP3,SLAIN1,FKBP5,TCOF1,GALNT10,GLCCI1,NGLY1,CBX4,TMEM131 |
| 2.268e-02 | -3.79 | GSE26669_CTRL_VS_COSTIM_BLOCK_MLR_CD8_TCELL_DN | MSigDB lists | GSE26669_CTRL_VS_COSTIM_BLOCK_MLR_CD8_TCELL_DN | 188 | 39 | 17377 | 2626 |
RAB14,FEZ2,GGNBP2,CDS2,GXYLT1,KIAA0100,DCAF15,PHRF1,DNAJB2,MAGED1,MXD4,MAPK14,CRLF3,PIP4K2A,SLC25A37,TBC1D14,GLTP,PIK3IP1,USP34,ADCY7,SNX2,ZMYND11,ZNF512,PPP1R21,MAN1B1,SLC16A7,CAMSAP1,ARHGDIB,PDE3B,POLR2A,VEZF1,VPS26B,MFAP1,AXIN1,DTX4,NCOA1,MZT2B,EYA2,CCDC137 |
| 2.268e-02 | -3.79 | GSE17186_MEMORY_VS_NAIVE_BCELL_DN | MSigDB lists | GSE17186_MEMORY_VS_NAIVE_BCELL_DN | 188 | 39 | 17377 | 2626 |
WSB2,PTMS,GOLIM4,LUZP1,RAC1,DBF4,XIAP,TKT,DLGAP4,KIF23,POMP,B4GALT4,RGS1,SSR1,FAM89B,PRC1,KIFAP3,AQR,MOB1A,RNF135,ARID4A,TMBIM1,MYO5A,PREB,VHL,MYBL2,LACTB,SMC2,KPNA4,ATP6V1D,ATAD2,RBL1,CAMKMT,C4orf46,ATP6V0C,CHEK2,SMAD1,ESPL1,S100PBP |
| 2.268e-02 | -3.79 | GSE26030_TH1_VS_TH17_DAY5_POST_POLARIZATION_UP | MSigDB lists | GSE26030_TH1_VS_TH17_DAY5_POST_POLARIZATION_UP | 188 | 39 | 17377 | 2626 |
MAX,PARP12,RRP15,AGRN,HLA-E,MRPL39,TOR3A,SLC25A12,NIT2,HMGN3,CUTC,PNO1,NVL,ZCCHC2,TPST1,SGCB,PPA1,NSUN4,LARS,TRAFD1,LAP3,NSUN2,PFKFB3,TOR1AIP2,IL12RB1,ISG15,ADSS,EPRS,KEAP1,PITX1,NLRC5,DTX4,PML,STAT1,CRCP,CHMP4B,NAA20,BYSL,RNF114 |
| 2.268e-02 | -3.79 | GSE4535_BM_DERIVED_DC_VS_FOLLICULAR_DC_UP | MSigDB lists | GSE4535_BM_DERIVED_DC_VS_FOLLICULAR_DC_UP | 188 | 39 | 17377 | 2626 |
PKP4,LUZP1,SLC41A1,SRGN,TFRC,SNRNP25,TNFAIP8,VMP1,IL6ST,FUT8,PTPN11,MDFIC,MGAT5,POU2AF1,BAK1,SNX25,MAPRE2,DDX24,ELL2,SNX2,DENND4C,ELP4,LNX2,NFATC2,IL12RB1,CBFB,GLOD4,FAS,ORMDL2,TFE3,GADD45B,ARNTL,ITGB1,CEBPG,AP1S1,ATF6,PGAM1,ZMAT3,SNX14 |
| 2.268e-02 | -3.79 | GSE43955_TH0_VS_TGFB_IL6_TH17_ACT_CD4_TCELL_10H_UP | MSigDB lists | GSE43955_TH0_VS_TGFB_IL6_TH17_ACT_CD4_TCELL_10H_UP | 188 | 39 | 17377 | 2626 |
SLC12A7,IER2,GALK1,EWSR1,NCKAP1,SLC20A1,ITGB5,LYN,BZW2,BCAP31,PABPC4,SPAG5,DECR1,NDUFA2,IL6ST,MBD2,PHTF1,CNOT6L,DNMT1,FYTTD1,NXT1,KLF10,SNX2,EMB,LDHA,PFKFB3,WDR82,SMC2,NDRG3,ZFAND5,ANKZF1,ETS2,ZHX1,E2F1,SLC16A1,RBPJ,SPRYD4,TRAF5,DDX52 |
| 2.268e-02 | -3.79 | GSE42021_TCONV_PLN_VS_CD24LO_TCONV_THYMUS_DN | MSigDB lists | GSE42021_TCONV_PLN_VS_CD24LO_TCONV_THYMUS_DN | 188 | 39 | 17377 | 2626 |
GOLIM4,UGP2,SDC2,MEF2A,MAP1LC3B,GGPS1,PAPOLA,SRXN1,GNS,RPA2,VAV1,SIAH1,RALB,AP3S2,TARDBP,MINPP1,TIPARP,PTPRK,USO1,NRAS,MKLN1,BIRC3,KAT7,EMB,EMP3,RRM2,SSR2,GLO1,ESYT1,GFER,POLR2A,PRDX1,XRCC5,BOLA3,ATP1A1,EIF4ENIF1,AXIN1,UBE2C,COIL |
| 2.268e-02 | -3.79 | GSE17301_ACD3_ACD28_VS_ACD3_ACD28_AND_IFNA2_STIM_CD8_TCELL_DN | MSigDB lists | GSE17301_ACD3_ACD28_VS_ACD3_ACD28_AND_IFNA2_STIM_CD8_TCELL_DN | 188 | 39 | 17377 | 2626 |
DDX58,UBL3,ARID5A,CLCC1,PCYOX1L,GNS,C1GALT1,PRKD3,SLC31A1,PRDM4,FUT8,ZNF200,TTC17,OGG1,ZNF189,BAK1,CYTH1,ARHGAP17,KLF10,COQ10B,LRBA,ATXN1,EDEM2,CBFA2T2,NDRG3,NEU1,OPTN,TRAM2,MAGT1,NIP7,CHD3,GADD45B,CTBS,TRIM32,PDLIM5,CHMP7,NAA60,ZC3HAV1,ADAM23 |
| 2.268e-02 | -3.79 | GSE5589_LPS_AND_IL10_VS_LPS_AND_IL6_STIM_IL6_KO_MACROPHAGE_45MIN_UP | MSigDB lists | GSE5589_LPS_AND_IL10_VS_LPS_AND_IL6_STIM_IL6_KO_MACROPHAGE_45MIN_UP | 188 | 39 | 17377 | 2626 |
DDX58,PARP12,TMEM184B,AGRN,TOR3A,PTTG1,TAP1,ARID5A,S1PR2,PSEN1,IL21R,LYN,CFLAR,IRF4,GOT2,DPYSL2,MBD2,AHSA1,ZCCHC2,SAP30,TRAFD1,SNX2,DENND1B,RABIF,NFATC2,AZI2,PSMB9,ISG15,HLA-B,TRIM26,DCK,MRPL27,NLRC5,PML,CHMP4B,RNASEL,RBPJ,RNF14,ZC3HAV1 |
| 2.271e-02 | -3.79 | REACTOME_SPHINGOLIPID_METABOLISM | MSigDB lists | REACTOME_SPHINGOLIPID_METABOLISM | 63 | 16 | 17377 | 2626 |
CSNK1G2,GALC,CERS6,HEXB,CERK,GBA,ASAH1,SUMF1,SUMF2,CTSA,SMPD4,PSAP,HEXA,ARSK,GM2A,NEU1 |
| 2.271e-02 | -3.79 | GO_SINGLE_STRANDED_RNA_BINDING | MSigDB lists | GO_SINGLE_STRANDED_RNA_BINDING | 63 | 16 | 17377 | 2626 |
DDX58,POLR2G,POLR2D,HNRNPF,TIA1,ATXN1,JMJD6,FXR1,EIF4H,PATL1,PABPC4,STRBP,SYNCRIP,EIF4A3,PABPC1,CBX4 |
| 2.271e-02 | -3.79 | TTGGGAG,MIR-150 | MSigDB lists | TTGGGAG,MIR-150 | 89 | 21 | 17377 | 2626 |
GGNBP2,PKP4,PLXNC1,TSC22D3,ZMYM5,TM9SF3,ARGLU1,IKBIP,ELK1,EIF4H,ERC1,VEZF1,PA2G4,GRIPAP1,DUSP3,RAD23B,MBD6,NR2F2,SEH1L,ZNF189,SMARCD1 |
| 2.271e-02 | -3.79 | ZAMORA_NOS2_TARGETS_DN | MSigDB lists | ZAMORA_NOS2_TARGETS_DN | 89 | 21 | 17377 | 2626 |
EIF5A,GALK1,FTL,GCLM,GMFG,MYH9,AP1B1,SOX4,VDAC1,PRPSAP1,MAP2K2,GNB2,APP,FKBP3,EIF2S2,ATP1A1,ATP6V0C,ACTB,STAT3,CD81,DDB1 |
| 2.271e-02 | -3.79 | EIF4E_UP | MSigDB lists | EIF4E_UP | 89 | 21 | 17377 | 2626 |
METTL1,SNX8,NTPCR,PPCS,MDH2,TUFM,BOLA1,RSAD1,PNO1,SRXN1,SNRNP25,EIF4A3,ACYP1,AHSA1,CHCHD1,GEMIN6,FN3KRP,JOSD1,TALDO1,MTX2,SSSCA1 |
| 2.271e-02 | -3.78 | GO_RETROMER_COMPLEX | MSigDB lists | GO_RETROMER_COMPLEX | 20 | 7 | 17377 | 2626 |
SNX8,SNX27,SNX2,VPS26B,RAB7A,VPS29,DCTN1 |
| 2.271e-02 | -3.78 | MODULE_439 | MSigDB lists | MODULE_439 | 20 | 7 | 17377 | 2626 |
PLK1,PCNA,CCNB1,BIRC5,LAP3,WRB,MYBL2 |
| 2.271e-02 | -3.78 | GO_NEGATIVE_REGULATION_OF_ANTIGEN_RECEPTOR_MEDIATED_SIGNALING_PATHWAY | MSigDB lists | GO_NEGATIVE_REGULATION_OF_ANTIGEN_RECEPTOR_MEDIATED_SIGNALING_PATHWAY | 20 | 7 | 17377 | 2626 |
PTPN2,EZR,PAWR,PLCL2,DUSP22,DUSP3,PRNP |
| 2.271e-02 | -3.78 | REACTOME_FORMATION_OF_INCISION_COMPLEX_IN_GG_NER | MSigDB lists | REACTOME_FORMATION_OF_INCISION_COMPLEX_IN_GG_NER | 20 | 7 | 17377 | 2626 |
RPA2,ERCC1,GTF2H2,DDB1,XPA,RAD23B,RPA1 |
| 2.271e-02 | -3.78 | GO_NEGATIVE_REGULATION_OF_PROTEIN_LOCALIZATION_TO_PLASMA_MEMBRANE | MSigDB lists | GO_NEGATIVE_REGULATION_OF_PROTEIN_LOCALIZATION_TO_PLASMA_MEMBRANE | 20 | 7 | 17377 | 2626 |
TGFB1,BCL2L1,PPP2R5A,CSK,GOPC,TMBIM1,NUMB |
| 2.271e-02 | -3.78 | GO_EXON_EXON_JUNCTION_COMPLEX | MSigDB lists | GO_EXON_EXON_JUNCTION_COMPLEX | 20 | 7 | 17377 | 2626 |
UPF2,UPF1,THRAP3,EIF4A3,RBM8A,SRSF1,RNPS1 |
| 2.271e-02 | -3.78 | GO_SNRNA_PROCESSING | MSigDB lists | GO_SNRNA_PROCESSING | 20 | 7 | 17377 | 2626 |
INTS2,INTS12,EXOSC9,EXOSC6,EXOSC7,INTS7,INTS1 |
| 2.271e-02 | -3.78 | BIOCARTA_ACTINY_PATHWAY | MSigDB lists | BIOCARTA_ACTINY_PATHWAY | 20 | 7 | 17377 | 2626 |
WASF2,NCKAP1,ARPC1A,NCK1,ARPC5,ACTR3,RAC1 |
| 2.271e-02 | -3.78 | GO_METHYL_CPG_BINDING | MSigDB lists | GO_METHYL_CPG_BINDING | 20 | 7 | 17377 | 2626 |
MBD1,ERH,CHTOP,MBD3,DNMT1,MECP2,MBD2 |
| 2.271e-02 | -3.78 | GO_NEGATIVE_REGULATION_OF_PROTEIN_LOCALIZATION_TO_CELL_PERIPHERY | MSigDB lists | GO_NEGATIVE_REGULATION_OF_PROTEIN_LOCALIZATION_TO_CELL_PERIPHERY | 20 | 7 | 17377 | 2626 |
TGFB1,BCL2L1,PPP2R5A,CSK,GOPC,TMBIM1,NUMB |
| 2.271e-02 | -3.78 | GO_NEGATIVE_REGULATION_OF_MACROAUTOPHAGY | MSigDB lists | GO_NEGATIVE_REGULATION_OF_MACROAUTOPHAGY | 20 | 7 | 17377 | 2626 |
TSC1,UBQLN4,CHMP4B,FEZ2,CHMP4A,CLN3,PHF23 |
| 2.275e-02 | -3.78 | ovary-carcinoma-mucinous_carcinoma | COSMIC cancer mutations | ovary-carcinoma-mucinous_carcinoma | 458 | 84 | 17385 | 2587 |
TP53RK,DNMT3A,TSC2,NF1,RPS6KA1,RAF1,CSNK2A1,SMARCA4,PRKACA,TWF2,LYN,MAPK14,EEF2K,CDK5,ABL2,PDK2,PRKD3,NEK6,SCYL3,CDK12,SRPK2,PLK1,PLK3,NRAS,BRD4,AKT2,PBK,TLK1,MAP4K4,PKMYT1,BRCA1,AURKB,STK17B,TRIM28,MAP3K4,JAK1,CLK3,STK38,HIPK2,LIMK1,FASTK,STK11,RNASEL,CHEK2,MAPK1,SMAD4,PRPF4B,SCYL1,TRIO,PRKAA1,CDK13,ADCK5,EIF2AK4,CSNK1A1,SCYL2,FGFR3,RB1,PTEN,DAPK1,PHKG2,CAMK2G,CSNK1G3,MSH6,PDPK1,CSNK1G2,NEK7,EIF2AK1,MAP4K3,KRAS,ARID1A,MARK2,MAP2K2,DAPK3,MAPK3,MASTL,GNAS,MAPK6,MAP3K5,CDK2,RPS6KC1,HIPK3,HRAS,NRBP1,CDKN2A |
| 2.276e-02 | -3.78 | nuclear inclusion body | cellular component | GO:0042405 | 12 | 5 | 18223 | 2701 |
ATXN1,NUP153,ATXN3,RAD18,SLF1 |
| 2.276e-02 | -3.78 | STAGA complex | cellular component | GO:0030914 | 12 | 5 | 18223 | 2701 |
TAF5L,TAF6L,TAF12,KAT2A,SUPT7L |
| 2.276e-02 | -3.78 | npBAF complex | cellular component | GO:0071564 | 12 | 5 | 18223 | 2701 |
SMARCA4,PHF10,ARID1A,SMARCE1,SMARCD1 |
| 2.276e-02 | -3.78 | aminoacyl-tRNA synthetase multienzyme complex | cellular component | GO:0017101 | 12 | 5 | 18223 | 2701 |
KARS,EPRS,LARS,IARS,QARS |
| 2.276e-02 | -3.78 | contractile ring | cellular component | GO:0070938 | 12 | 5 | 18223 | 2701 |
MYH9,PDXP,ANLN,PRC1,RTKN |
| 2.276e-02 | -3.78 | condensed nuclear chromosome kinetochore | cellular component | GO:0000778 | 12 | 5 | 18223 | 2701 |
PLK1,NUF2,DSN1,CCNB1,MIS12 |
| 2.276e-02 | -3.78 | proteasome regulatory particle, base subcomplex | cellular component | GO:0008540 | 12 | 5 | 18223 | 2701 |
PSMD2,PSMD1,PSMD9,PSMC1,PSMC4 |
| 2.276e-02 | -3.78 | methylosome | cellular component | GO:0034709 | 12 | 5 | 18223 | 2701 |
ERH,SNRPG,SNRPD3,SNRPB,CLNS1A |
| 2.277e-02 | -3.78 | RYTTCCTG_V$ETS2_B | MSigDB lists | RYTTCCTG_V$ETS2_B | 1013 | 176 | 17377 | 2626 |
GPR132,ST13,ADAM10,ABCC10,AGPAT1,DHX8,SND1,S1PR2,MAPK14,PPP1R16B,CMTM6,CREM,CDK5,ETV6,DNM2,AP2B1,SLC35C2,DNMT1,ZNF800,KCNAB2,CDC37,SP3,BAZ2A,NCK1,LNX2,LRP5,ARHGDIB,SLC25A5,STX16,FOXRED1,DHX15,ARF4,KRIT1,UBTF,HHEX,SEPT1,TBC1D17,WAS,WDR11,TPP2,MYO18A,ITGB1,PTPN7,CAB39,ACTB,ARRB2,ZMAT3,LIME1,PPP1R12A,CLSPN,DHPS,ZNF768,CIB1,ACAP1,CTCF,NDUFA4,SLC4A2,XPNPEP3,VPS25,RTKN,FBRS,MCTS1,VASP,ZNRF2,RINL,CAPZA1,AFF1,EIF5A,CYFIP1,AMD1,EXOSC9,GORASP2,MAP7D1,PLEC,PATL1,ARHGAP15,GALNT2,ORMDL2,DCK,LPCAT4,ARAP1,APPL2,CTSA,RBBP4,TCF12,ZNF207,ZNF296,TRIM41,ASH1L,SARNP,GGNBP2,TRERF1,TRIP10,RAB11B,CAST,RAC1,TM9SF3,CREBL2,PRKACA,LYN,TMEM161B,RPL11,MOAP1,VAV1,TMEM69,SHC1,STRBP,SH3BP1,RALB,TMEM136,CDK12,RLIM,MOSPD1,ACSL5,PPIF,CLCN3,ERF,KIAA0040,MAP4K4,E2F3,ATXN1,WIPF1,NFATC2,ALKBH6,EIF3K,ZNF282,DAP3,SEC61A1,TAB2,NSMCE2,RWDD4,RHEBL1,CMAS,SH2D3A,GOLPH3L,SESTD1,PDAP1,ZFP91,DCTN2,CDK2AP2,CHIC2,AKT1S1,ETS1,RAB11A,FOXO3,PIP4K2A,FZD6,FERMT3,WWP2,PDCD10,CTSS,PTEN,SEC24C,PELO,PTPN11,ARHGEF2,TAGLN2,CNN2,CITED2,SPTAN1,PDLIM2,TTPAL,YTHDC1,PPP1R9B,NASP,LRRC1,WDR81,PICALM,YIF1A,FAM110A,TFE3,PSAP,RBPJ,YWHAH,PURA,DEF6 |
| 2.280e-02 | -3.78 | Photodynamic therapy-induced AP-1 survival signaling. | WikiPathways | WP3611 | 51 | 14 | 5312 | 837 |
BAK1,RB1,CCNA2,BCL2,MCL1,BCL2L1,ELK1,MAP3K5,MAPK14,ATF2,TRAF5,CDKN2A,CFLAR,FAS |
| 2.286e-02 | -3.78 | GO_ENDODEOXYRIBONUCLEASE_ACTIVITY | MSigDB lists | GO_ENDODEOXYRIBONUCLEASE_ACTIVITY | 48 | 13 | 17377 | 2626 |
RAD51C,ERCC1,TATDN2,NEIL3,XRCC2,XRCC3,DCLRE1C,TATDN1,GEN1,OGG1,RAD51D,NEIL2,MBD4 |
| 2.286e-02 | -3.78 | APRELIKOVA_BRCA1_TARGETS | MSigDB lists | APRELIKOVA_BRCA1_TARGETS | 48 | 13 | 17377 | 2626 |
RPA2,EPRS,DDX24,ANXA5,DNAJA1,TCEA1,ARF1,RIT1,PSMC1,STAM,APP,NUMB,SPTAN1 |
| 2.286e-02 | -3.78 | PRAMOONJAGO_SOX4_TARGETS_DN | MSigDB lists | PRAMOONJAGO_SOX4_TARGETS_DN | 48 | 13 | 17377 | 2626 |
MLEC,SIGMAR1,BIRC5,TMEM97,CCNB1,CLN3,LY6E,ARRB2,TMEM14A,MAP2K2,TMED2,GCSH,PDCD4 |
| 2.286e-02 | -3.78 | MODULE_485 | MSigDB lists | MODULE_485 | 48 | 13 | 17377 | 2626 |
PDK2,ZNF777,PCNA,CCNA2,POLE,GSDMB,NQO1,RBM42,SNRPB,BDH1,MYBL2,RRM2,CDC6 |
| 2.286e-02 | -3.78 | GO_CELLULAR_MODIFIED_AMINO_ACID_BIOSYNTHETIC_PROCESS | MSigDB lists | GO_CELLULAR_MODIFIED_AMINO_ACID_BIOSYNTHETIC_PROCESS | 48 | 13 | 17377 | 2626 |
MAT2B,SEPHS2,GCLM,MTHFD2,GART,DHPS,ATIC,AHCY,CHAC2,ALDH18A1,HAGH,PTDSS1,MAT2A |
| 2.286e-02 | -3.78 | GTAAACC,MIR-299-5P | MSigDB lists | GTAAACC,MIR-299-5P | 48 | 13 | 17377 | 2626 |
PPP2R5A,INPP5A,SIAH1,MECP2,CS,CAB39,CTCF,SOX4,H3F3A,TIPARP,CPEB2,MAT2A,CNOT3 |
| 2.289e-02 | -3.78 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex | KEGG pathways | hsa_M00146 | 15 | 6 | 7161 | 1149 |
NDUFA4,NDUFA5,NDUFA7,NDUFA2,NDUFA3,NDUFA11 |
| 2.289e-02 | -3.78 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex | KEGG pathways | M00146 | 15 | 6 | 7161 | 1149 |
NDUFA4,NDUFA5,NDUFA7,NDUFA2,NDUFA3,NDUFA11 |
| 2.290e-02 | -3.78 | YTHDF1 (YTH N6-methyladenosine RNA binding protein 1) | protein interactions | 54915 | 59 | 16 | 17029 | 2761 |
TMEM184B,NQO1,AGO2,CUL3,YTHDF3,FAM136A,CDIPT,MCM2,RPA1,USP5,RPA2,SYNCRIP,LRSAM1,POT1,FAF1,DCTN1 |
| 2.290e-02 | -3.78 | TXN2 (thioredoxin 2) | protein interactions | 25828 | 59 | 16 | 17029 | 2761 |
MAPRE2,GOLIM4,TXN,ANXA6,AGTRAP,UCHL5,PPCDC,ILF3,RPL8,AP2B1,DCTD,SSNA1,MRFAP1L1,MAP3K5,SNRNP70,SCYL3 |
| 2.290e-02 | -3.78 | UCHL1 (ubiquitin C-terminal hydrolase L1) | protein interactions | 7345 | 59 | 16 | 17029 | 2761 |
TERF2IP,CDK5,DERL1,MDM2,CCDC14,AKT2,CDKN1B,WDR82,ADRB2,UBE2I,CDK2,USP21,APP,CDKN2A,DDB1,TERF2 |
| 2.290e-02 | -3.78 | CDK18 (cyclin dependent kinase 18) | protein interactions | 5129 | 59 | 16 | 17029 | 2761 |
CDK5,CCNK,MAGED2,GOLGA2,NSRP1,MTA2,FAAP100,FKBP5,RAB3IP,FXR1,PPP5C,RBM4,MTR,APP,CDC37,MASTL |
| 2.290e-02 | -3.78 | POLR2J (RNA polymerase II subunit J) | protein interactions | 5439 | 59 | 16 | 17029 | 2761 |
RPAP3,CTDP1,POLR2G,AATF,POLR2K,ELOA,POLR2D,BRCA1,PSMB9,POLR2A,GTF2F1,MED10,RPAP1,ASB6,RPRD1B,DDB1 |
| 2.290e-02 | -3.78 | MEF2A (myocyte enhancer factor 2A) | protein interactions | 4205 | 59 | 16 | 17029 | 2761 |
PHB2,MAPKAPK3,MEF2A,MEF2D,ERBIN,UBE2I,MAPK14,GNB2,CDK5,SMAD2,HDAC7,ITGB1,CABIN1,NDUFB9,SMAD4,DDB1 |
| 2.290e-02 | -3.78 | RPGRIP1 (RPGR interacting protein 1) | protein interactions | 57096 | 59 | 16 | 17029 | 2761 |
NPHP4,RBM8A,ADSL,BRCA1,HAUS8,CHCHD3,DLG5,PCM1,NAP1L1,KIF14,AEN,GPATCH1,TP53BP2,NAP1L4,ECD,ZNF564 |
| 2.290e-02 | -3.78 | HNRNPLL (heterogeneous nuclear ribonucleoprotein L like) | protein interactions | 92906 | 59 | 16 | 17029 | 2761 |
JMJD4,FAM208B,VHL,ATXN1,UBE2I,CCNB1,PCBP1,CNOT3,RAVER2,PAF1,MINPP1,CCNB2,FAM208A,PDIA6,N4BP2L2,CDC5L |
| 2.290e-02 | -3.78 | DNAAF5 (dynein axonemal assembly factor 5) | protein interactions | 54919 | 59 | 16 | 17029 | 2761 |
PLK1,METTL1,MAGED1,ACTR3,HNRNPF,RRM2,PTP4A3,NPLOC4,PTPRF,GSTK1,GRK2,RAD23B,PGRMC1,CHMP4B,MAPK1,CSTF1 |
| 2.294e-02 | -3.77 | F-box | pfam domains | PF00646 | 16 | 6 | 17054 | 2545 |
FBXO28,KDM2A,CCNF,FBXL19,FBXO22,FBXO5 |
| 2.294e-02 | -3.77 | BAKKER_FOXO3_TARGETS_UP | MSigDB lists | BAKKER_FOXO3_TARGETS_UP | 58 | 15 | 17377 | 2626 |
VOPP1,AMPD2,PGGT1B,NQO2,CDKN1B,ASAH1,DCP1A,PIK3IP1,XPO7,CITED2,RGS2,GNAI2,KLF6,GLCCI1,TMX1 |
| 2.294e-02 | -3.77 | PID_ATF2_PATHWAY | MSigDB lists | PID_ATF2_PATHWAY | 58 | 15 | 17377 | 2626 |
RB1,CCNA2,NF1,CUL3,H2AFY,BCL2,RUVBL2,BCL2L1,BRCA1,CREB1,MAPK14,CBFB,MAPK1,ATF2,MAPK3 |
| 2.299e-02 | -3.77 | MAPK targets/ Nuclear events mediated by MAP kinases | REACTOME pathways | R-HSA-450282 | 31 | 10 | 10287 | 1696 |
PPP2CA,DUSP3,RPS6KA1,MEF2A,ELK1,CREB1,MAPK14,MAPK1,ATF2,MAPK3 |
| 2.299e-02 | -3.77 | Activation of BH3-only proteins | REACTOME pathways | R-HSA-114452 | 31 | 10 | 10287 | 1696 |
AKT2,DYNLL1,TFDP1,E2F1,PPP3R1,YWHAZ,BCL2,TP53BP2,TFDP2,YWHAH |
| 2.299e-02 | -3.77 | Extension of Telomeres | REACTOME pathways | R-HSA-180786 | 31 | 10 | 10287 | 1696 |
POLA2,RPA2,PCNA,RFC3,POLE,PRIM2,RUVBL2,RFC2,PRIM1,RPA1 |
| 2.301e-02 | -3.77 | macromolecule deacylation | biological process | GO:0098732 | 73 | 18 | 17256 | 2622 |
PPT1,BAZ2A,MTA2,MIER1,RCOR1,MIER2,SIRT2,MBD3,BRMS1,CHD3,HDAC7,MTA1,RBBP4,SAP30L,ARID4A,LYPLA2,HDAC2,SAP30 |
| 2.301e-02 | -3.77 | isomerase activity | molecular function | GO:0016853 | 152 | 33 | 17224 | 2647 |
MIF,PPIB,MUT,GNPDA1,MRI1,GNE,TMX4,TMX3,TOP2B,FKBP2,QSOX2,EBP,FKBP1A,CWC27,PPIG,PIN1,PPIL2,PTGES3,TOP1MT,PDIA6,TMX1,PPIF,TSTA3,PPIE,ERO1A,TOP3A,PPWD1,FKBP3,ECH1,NAXE,FKBP5,GPI,PGAM1 |
| 2.301e-02 | -3.77 | IKEDA_MIR1_TARGETS_UP | MSigDB lists | IKEDA_MIR1_TARGETS_UP | 53 | 14 | 17377 | 2626 |
SMAP1,PDCD10,SYNCRIP,HNRNPR,SF3B1,CORO1C,RRBP1,YWHAZ,ANP32E,CITED2,PICALM,ARF4,PDCD4,CREM |
| 2.301e-02 | -3.77 | GO_RNA_POLYMERASE_II_CORE_PROMOTER_SEQUENCE_SPECIFIC_DNA_BINDING | MSigDB lists | GO_RNA_POLYMERASE_II_CORE_PROMOTER_SEQUENCE_SPECIFIC_DNA_BINDING | 53 | 14 | 17377 | 2626 |
SP3,H2AFZ,STAT6,SUZ12,NFIL3,ZNF335,STAT1,WBP2,NLRC5,H2AFY,RBPJ,RUVBL2,SMAD1,H3F3A |
| 2.301e-02 | -3.77 | KYNG_ENVIRONMENTAL_STRESS_RESPONSE_UP | MSigDB lists | KYNG_ENVIRONMENTAL_STRESS_RESPONSE_UP | 53 | 14 | 17377 | 2626 |
CSDE1,HNRNPA2B1,EIF3L,GOLGA4,GALNT2,ITGB8,FLOT1,CTCF,CYCS,CCNL2,POMP,SGCB,OAZ1,RHOB |
| 2.302e-02 | -3.77 | MTNR1A (melatonin receptor 1A) | protein interactions | 4543 | 160 | 36 | 17029 | 2761 |
TRIP12,RAC1,ABHD14B,PSMD2,RAP1A,KLHL5,KLHL20,ATIC,SRI,NAP1L4,PDIA6,GNAI2,LRRC59,USP34,NASP,DPM1,CUL3,COG1,KRAS,CAND1,HMGN2,NAP1L1,SURF4,ATP5MC3,TPP2,PGRMC1,USP32,BAZ1B,ACTB,YWHAZ,MYO9A,TMEM14A,TUBB,SNAPIN,DDX52,TMEM33 |
| 2.308e-02 | -3.77 | protein localization to nuclear inner membrane | biological process | GO:0036228 | 2 | 2 | 17256 | 2622 |
NUP155,NUP54 |
| 2.308e-02 | -3.77 | trimming of first mannose on A branch | biological process | GO:0036511 | 2 | 2 | 17256 | 2622 |
EDEM2,MAN1B1 |
| 2.308e-02 | -3.77 | cellular response to Thyroglobulin triiodothyronine | biological process | GO:1904017 | 2 | 2 | 17256 | 2622 |
NCOA1,NCOA2 |
| 2.308e-02 | -3.77 | positive regulation of cardiolipin metabolic process | biological process | GO:1900210 | 2 | 2 | 17256 | 2622 |
TAZ,STOML2 |
| 2.308e-02 | -3.77 | resolution of recombination intermediates | biological process | GO:0071139 | 2 | 2 | 17256 | 2622 |
XRCC3,GEN1 |
| 2.308e-02 | -3.77 | regulation of cardiolipin metabolic process | biological process | GO:1900208 | 2 | 2 | 17256 | 2622 |
TAZ,STOML2 |
| 2.308e-02 | -3.77 | uropod organization | biological process | GO:0032796 | 2 | 2 | 17256 | 2622 |
MYH9,CORO1A |
| 2.308e-02 | -3.77 | Golgi calcium ion transport | biological process | GO:0032472 | 2 | 2 | 17256 | 2622 |
TMEM165,ATP2C1 |
| 2.308e-02 | -3.77 | regulation of DNA helicase activity | biological process | GO:1905774 | 2 | 2 | 17256 | 2622 |
MCM2,POT1 |
| 2.308e-02 | -3.77 | negative regulation of ubiquitin-specific protease activity | biological process | GO:2000157 | 2 | 2 | 17256 | 2622 |
PARK7,UBXN1 |
| 2.308e-02 | -3.77 | glucosamine-containing compound biosynthetic process | biological process | GO:1901073 | 2 | 2 | 17256 | 2622 |
NANP,GNE |
| 2.308e-02 | -3.77 | glutaminyl-tRNA aminoacylation | biological process | GO:0006425 | 2 | 2 | 17256 | 2622 |
LARS,QARS |
| 2.308e-02 | -3.77 | histone H3-K14 acetylation | biological process | GO:0044154 | 2 | 2 | 17256 | 2622 |
KAT2A,MEAF6 |
| 2.308e-02 | -3.77 | negative regulation of exonuclease activity | biological process | GO:1905778 | 2 | 2 | 17256 | 2622 |
TERF1,TERF2 |
| 2.308e-02 | -3.77 | xylulose biosynthetic process | biological process | GO:0005999 | 2 | 2 | 17256 | 2622 |
TALDO1,TKT |
| 2.308e-02 | -3.77 | positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia | biological process | GO:2000777 | 2 | 2 | 17256 | 2622 |
PLK3,SIRT2 |
| 2.308e-02 | -3.77 | skeletal muscle satellite cell migration | biological process | GO:1902766 | 2 | 2 | 17256 | 2622 |
RHOA,RHOC |
| 2.308e-02 | -3.77 | regulation of DNA recombination at telomere | biological process | GO:0072695 | 2 | 2 | 17256 | 2622 |
TERF2IP,TERF2 |
| 2.308e-02 | -3.77 | diphosphate metabolic process | biological process | GO:0071344 | 2 | 2 | 17256 | 2622 |
PPA1,PPA2 |
| 2.308e-02 | -3.77 | generation of catalytic spliceosome for first transesterification step | biological process | GO:0000349 | 2 | 2 | 17256 | 2622 |
XAB2,PRPF19 |
| 2.308e-02 | -3.77 | positive regulation of L-glutamate import across plasma membrane | biological process | GO:0002038 | 2 | 2 | 17256 | 2622 |
PSEN1,ARL6IP1 |
| 2.308e-02 | -3.77 | basophil activation involved in immune response | biological process | GO:0002276 | 2 | 2 | 17256 | 2622 |
KARS,PI4K2A |
| 2.308e-02 | -3.77 | negative regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway | biological process | GO:1905259 | 2 | 2 | 17256 | 2622 |
DNAJA1,PARK7 |
| 2.308e-02 | -3.77 | cellular response to methylglyoxal | biological process | GO:0097238 | 2 | 2 | 17256 | 2622 |
AKR1B1,PARK7 |
| 2.308e-02 | -3.77 | negative regulation of protein localization to chromosome, telomeric region | biological process | GO:1904815 | 2 | 2 | 17256 | 2622 |
H2AFY,TERF1 |
| 2.308e-02 | -3.77 | primary lung bud formation | biological process | GO:0060431 | 2 | 2 | 17256 | 2622 |
HHEX,RDH10 |
| 2.308e-02 | -3.77 | isoleucine catabolic process | biological process | GO:0006550 | 2 | 2 | 17256 | 2622 |
ACAT1,BCAT2 |
| 2.308e-02 | -3.77 | trimming of second mannose on A branch | biological process | GO:0036512 | 2 | 2 | 17256 | 2622 |
EDEM2,MAN1B1 |
| 2.308e-02 | -3.77 | regulation of telomere maintenance via semi-conservative replication | biological process | GO:0032213 | 2 | 2 | 17256 | 2622 |
TERF1,TERF2 |
| 2.308e-02 | -3.77 | negative regulation of telomeric loop disassembly | biological process | GO:1904534 | 2 | 2 | 17256 | 2622 |
TERF1,TERF2 |
| 2.308e-02 | -3.77 | recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex | biological process | GO:0034402 | 2 | 2 | 17256 | 2622 |
CDC73,POLR2D |
| 2.308e-02 | -3.77 | pyrimidine nucleotide transport | biological process | GO:0006864 | 2 | 2 | 17256 | 2622 |
SLC25A33,SLC25A36 |
| 2.308e-02 | -3.77 | forebrain astrocyte development | biological process | GO:0021897 | 2 | 2 | 17256 | 2622 |
KRAS,NF1 |
| 2.308e-02 | -3.77 | negative regulation of telomere maintenance via semi-conservative replication | biological process | GO:0032214 | 2 | 2 | 17256 | 2622 |
TERF1,TERF2 |
| 2.308e-02 | -3.77 | N-acetylglucosamine biosynthetic process | biological process | GO:0006045 | 2 | 2 | 17256 | 2622 |
NANP,GNE |
| 2.308e-02 | -3.77 | positive regulation of ligand-dependent nuclear receptor transcription coactivator activity | biological process | GO:2000327 | 2 | 2 | 17256 | 2622 |
CNOT9,CNOT6 |
| 2.308e-02 | -3.77 | cytosol to ER transport | biological process | GO:0046967 | 2 | 2 | 17256 | 2622 |
TAP2,TAP1 |
| 2.308e-02 | -3.77 | trimming of terminal mannose on B branch | biological process | GO:0036509 | 2 | 2 | 17256 | 2622 |
EDEM2,MAN1B1 |
| 2.308e-02 | -3.77 | resolution of mitotic recombination intermediates | biological process | GO:0071140 | 2 | 2 | 17256 | 2622 |
XRCC3,GEN1 |
| 2.308e-02 | -3.77 | tRNA (guanine-N7)-methylation | biological process | GO:0106004 | 2 | 2 | 17256 | 2622 |
METTL1,WDR4 |
| 2.308e-02 | -3.77 | double-strand break repair via alternative nonhomologous end joining | biological process | GO:0097681 | 2 | 2 | 17256 | 2622 |
PRKDC,POLQ |
| 2.308e-02 | -3.77 | negative regulation of telomeric D-loop disassembly | biological process | GO:1905839 | 2 | 2 | 17256 | 2622 |
TERF1,TERF2 |
| 2.308e-02 | -3.77 | isoleucyl-tRNA aminoacylation | biological process | GO:0006428 | 2 | 2 | 17256 | 2622 |
IARS,IARS2 |
| 2.308e-02 | -3.77 | negative regulation of DNA recombination at telomere | biological process | GO:0048239 | 2 | 2 | 17256 | 2622 |
TERF2IP,TERF2 |
| 2.308e-02 | -3.77 | smooth endoplasmic reticulum calcium ion homeostasis | biological process | GO:0051563 | 2 | 2 | 17256 | 2622 |
PSEN1,APP |
| 2.308e-02 | -3.77 | formation of cytoplasmic translation initiation complex | biological process | GO:0001732 | 2 | 2 | 17256 | 2622 |
EIF3D,EIF3A |
| 2.308e-02 | -3.77 | phosphatidylinositol 5-phosphate metabolic process | biological process | GO:1904562 | 2 | 2 | 17256 | 2622 |
MTMR3,PIKFYVE |
| 2.308e-02 | -3.77 | regulation of vesicle targeting, to, from or within Golgi | biological process | GO:0048209 | 2 | 2 | 17256 | 2622 |
GOSR1,PREB |
| 2.308e-02 | -3.77 | Golgi vesicle docking | biological process | GO:0048211 | 2 | 2 | 17256 | 2622 |
USO1,NSF |
| 2.308e-02 | -3.77 | negative regulation of protein K48-linked deubiquitination | biological process | GO:1903094 | 2 | 2 | 17256 | 2622 |
PARK7,UBXN1 |
| 2.308e-02 | -3.77 | forebrain astrocyte differentiation | biological process | GO:0021896 | 2 | 2 | 17256 | 2622 |
KRAS,NF1 |
| 2.308e-02 | -3.77 | regulation of telomeric D-loop disassembly | biological process | GO:1905838 | 2 | 2 | 17256 | 2622 |
TERF1,TERF2 |
| 2.308e-02 | -3.77 | cis assembly of pre-catalytic spliceosome | biological process | GO:0000354 | 2 | 2 | 17256 | 2622 |
SNRNP200,DDX23 |
| 2.308e-02 | -3.77 | protein localization to Golgi membrane | biological process | GO:1903292 | 2 | 2 | 17256 | 2622 |
ARL5B,ARL5A |
| 2.308e-02 | -3.77 | antigen processing and presentation of endogenous peptide antigen via MHC class Ib | biological process | GO:0002476 | 2 | 2 | 17256 | 2622 |
TAP2,HLA-E |
| 2.308e-02 | -3.77 | regulation of Fas signaling pathway | biological process | GO:1902044 | 2 | 2 | 17256 | 2622 |
SP100,TMBIM1 |
| 2.308e-02 | -3.77 | macrophage apoptotic process | biological process | GO:0071888 | 2 | 2 | 17256 | 2622 |
CTSL,IRF3 |
| 2.308e-02 | -3.77 | pyrimidine nucleotide import into mitochondrion | biological process | GO:1990519 | 2 | 2 | 17256 | 2622 |
SLC25A33,SLC25A36 |
| 2.308e-02 | -3.77 | regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway | biological process | GO:1905258 | 2 | 2 | 17256 | 2622 |
DNAJA1,PARK7 |
| 2.308e-02 | -3.77 | recycling endosome to Golgi transport | biological process | GO:0071955 | 2 | 2 | 17256 | 2622 |
GCC2,TBC1D14 |
| 2.309e-02 | -3.77 | Amino Acid metabolism | WikiPathways | WP3925 | 91 | 22 | 5312 | 837 |
SRM,GCLM,SUCLG1,MUT,MDH2,MCCC1,LDHA,GLUD1,OGDH,OAT,PKM,ODC1,PDHX,SDHA,EPRS,IARS,GOT2,CS,ACLY,MDH1,ACADM,ALDH18A1 |
| 2.309e-02 | -3.77 | T-Cell antigen Receptor (TCR) Signaling Pathway | WikiPathways | WP69 | 91 | 22 | 5312 | 837 |
PDPK1,TGFB1,NCK1,RAF1,NFATC2,MAPK14,MAP2K2,MAPK3,FAS,VAV1,CRKL,IRF4,WAS,CDC42,SHC1,PIK3R2,PTPN11,MAP3K14,CREB1,ATF2,MAPK1,HRAS |
| 2.310e-02 | -3.77 | HDR through Homologous Recombination (HR) or Single Strand Annealing (SSA) | REACTOME pathways | R-HSA-5693567 | 132 | 31 | 10287 | 1696 |
ERCC1,RFC3,CLSPN,POLK,RAD51AP1,SUMO2,BABAM1,RMI2,TOP3A,BRCA1,BLM,UBE2I,RFC2,RMI1,RPA1,RPA2,RAD51C,PCNA,CCNA2,BABAM2,PALB2,POLE,RPS27A,XRCC2,H2AFX,TIMELESS,XRCC3,CDK2,GEN1,SPIDR,RAD51D |
| 2.312e-02 | -3.77 | desmoid_tumour-fibromatosis | COSMIC cancer mutations | desmoid_tumour-fibromatosis | 12 | 5 | 17385 | 2587 |
RB1,KRAS,FUS,CDKN2A,ETV6 |
| 2.312e-02 | -3.77 | trachea | COSMIC cancer mutations | trachea | 12 | 5 | 17385 | 2587 |
KRAS,NRAS,PTEN,HRAS,CDKN2A |
| 2.312e-02 | -3.77 | haematopoietic_and_lymphoid_tissue-mediastinum-lymphoid_neoplasm-diffuse_large_B_cell_lymphoma | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-mediastinum-lymphoid_neoplasm-diffuse_large_B_cell_lymphoma | 12 | 5 | 17385 | 2587 |
CDKN2C,KRAS,TNFAIP3,STAT3,CDKN2A |
| 2.312e-02 | -3.77 | skin-face-carcinoma-basal_cell_carcinoma | COSMIC cancer mutations | skin-face-carcinoma-basal_cell_carcinoma | 12 | 5 | 17385 | 2587 |
FGFR3,KRAS,CYLD,NRAS,HRAS |
| 2.312e-02 | -3.77 | skin-abdomen-malignant_melanoma-nodular | COSMIC cancer mutations | skin-abdomen-malignant_melanoma-nodular | 12 | 5 | 17385 | 2587 |
KRAS,NRAS,PTEN,HRAS,CDKN2A |
| 2.312e-02 | -3.77 | central_nervous_system-fourth_ventricle-glioma-astrocytoma_Grade_I | COSMIC cancer mutations | central_nervous_system-fourth_ventricle-glioma-astrocytoma_Grade_I | 12 | 5 | 17385 | 2587 |
KRAS,NRAS,HRAS,PTPN11,CLCN6 |
| 2.312e-02 | -3.77 | soft_tissue-fibrous_tissue_and_uncertain_origin-desmoid_tumour-fibromatosis | COSMIC cancer mutations | soft_tissue-fibrous_tissue_and_uncertain_origin-desmoid_tumour-fibromatosis | 12 | 5 | 17385 | 2587 |
RB1,KRAS,FUS,CDKN2A,ETV6 |
| 2.312e-02 | -3.77 | adrenal_gland-adrenal_gland-adrenal_cortical_adenoma | COSMIC cancer mutations | adrenal_gland-adrenal_gland-adrenal_cortical_adenoma | 12 | 5 | 17385 | 2587 |
GNAS,KRAS,NRAS,MEN1,HRAS |
| 2.313e-02 | -3.77 | GSE12963_ENV_NEF_VS_ENV_NEF_AND_VPR_DEFICIENT_HIV1_INF_CD4_TCELL_UP | MSigDB lists | GSE12963_ENV_NEF_VS_ENV_NEF_AND_VPR_DEFICIENT_HIV1_INF_CD4_TCELL_UP | 116 | 26 | 17377 | 2626 |
CCDC93,NCOR2,STAU1,BAZ2A,MECP2,TOR3A,EHMT1,TRAK1,BRAP,B4GALT1,SIKE1,MAP4K3,SLC20A1,ZADH2,DNAJB9,FBRS,DDX23,GRIPAP1,DHX16,L3MBTL3,ZCCHC2,PML,KHSRP,ESYT2,ZBTB24,CWC25 |
| 2.313e-02 | -3.77 | NELFCD (negative elongation factor complex member C/D) | protein interactions | 51497 | 45 | 13 | 17029 | 2761 |
COX5B,EPRS,ATP1A1,SERF2,PHB2,RPS14,MTA1,COX5A,COX4I1,DNAJA1,RPS26,SMAD4,COPB2 |
| 2.313e-02 | -3.77 | IL4R (interleukin 4 receptor) | protein interactions | 3566 | 45 | 13 | 17029 | 2761 |
ANKLE2,HGS,RHOBTB3,SHC1,JAK1,GOLGA2,NET1,STAT6,PTPN11,PKMYT1,ARL5B,RHBDF2,SOCS5 |
| 2.313e-02 | -3.77 | RNF19B (ring finger protein 19B) | protein interactions | 127544 | 45 | 13 | 17029 | 2761 |
CDC27,WDR11,DNAJB2,PIK3R2,HSDL1,AP1M1,ATP6V0A1,LTN1,USP22,FBL,ARL17A,WDR48,XPR1 |
| 2.313e-02 | -3.77 | ZNF281 (zinc finger protein 281) | protein interactions | 23528 | 45 | 13 | 17029 | 2761 |
MAGED2,CDC16,USP10,CHMP4B,TAP2,FBL,STAT3,TERF1,KCNAB2,ISG15,TERF2,NIPSNAP1,EGLN1 |
| 2.313e-02 | -3.77 | MRPL16 (mitochondrial ribosomal protein L16) | protein interactions | 54948 | 45 | 13 | 17029 | 2761 |
MRPL50,MRPL2,MRPL9,CYLD,MRPL42,MRPL39,MRPL12,MRPL40,ANLN,MRPL11,MRPL13,MRPL19,RPL23A |
| 2.313e-02 | -3.77 | HMMR (hyaluronan mediated motility receptor) | protein interactions | 3161 | 45 | 13 | 17029 | 2761 |
PCM1,DYNLL1,FAM83D,TPX2,ACTB,BRCA1,CSNK1A1,MAPK1,HMG20A,NMD3,CSNK1D,MAPK3,DCTN1 |
| 2.313e-02 | -3.77 | ST13 (ST13, Hsp70 interacting protein) | protein interactions | 6767 | 45 | 13 | 17029 | 2761 |
CPNE1,SUB1,CLIC4,HSPA4,SMAD2,CDC42,VAV2,DAPK1,MSH2,FUS,CDK2,PSEN1,DPYSL3 |
| 2.316e-02 | -3.77 | MODULE_356 | MSigDB lists | MODULE_356 | 149 | 32 | 17377 | 2626 |
TGFB1,RPLP2,RNASEH2C,NCK1,EID1,PHRF1,MECP2,OXR1,CRNKL1,TMEM97,NUP54,PLAGL2,RABIF,CDC42SE2,ELK1,SLC20A1,LYN,POFUT1,PICALM,SLC25A37,RXRB,TRIM4,PSMD2,CLIC4,TXNDC16,PFDN4,DBNDD1,WNT5B,PPP4R1,EFTUD2,H3F3A,SLC25A1 |
| 2.317e-02 | -3.77 | ErbB1 downstream signaling | Pathway Interaction DB | erbb1_downstream_pathway | 102 | 28 | 2226 | 426 |
PDPK1,WASF2,RAF1,RAC1,ACTR3,VAV2,NCKAP1,ELK1,CYFIP2,MAP2K2,ARF4,MAPK3,CAPN2,PPP2CA,CALM2,CDC42,ARPC5,STAT1,YWHAZ,CREB1,PPP5C,SMAD1,YWHAH,STAT3,MAPK1,ATF2,ABI1,MLST8 |
| 2.319e-02 | -3.76 | oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor | molecular function | GO:0016670 | 8 | 4 | 17224 | 2647 |
GFER,QSOX2,PCYOX1L,TMX3 |
| 2.319e-02 | -3.76 | primary miRNA binding | molecular function | GO:0070878 | 8 | 4 | 17224 | 2647 |
DDX5,SMAD2,SMAD1,DGCR8 |
| 2.319e-02 | -3.76 | RNA polymerase I regulatory region sequence-specific DNA binding | molecular function | GO:0001163 | 8 | 4 | 17224 | 2647 |
SMARCA4,UBTF,RRN3,BAZ2A |
| 2.319e-02 | -3.76 | mismatch repair complex binding | molecular function | GO:0032404 | 8 | 4 | 17224 | 2647 |
PCNA,MSH6,PMS2,MSH2 |
| 2.319e-02 | -3.76 | peroxiredoxin activity | molecular function | GO:0051920 | 8 | 4 | 17224 | 2647 |
PRDX3,PARK7,PRDX5,PRDX1 |
| 2.319e-02 | -3.76 | RNA polymerase I regulatory region DNA binding | molecular function | GO:0001013 | 8 | 4 | 17224 | 2647 |
SMARCA4,UBTF,RRN3,BAZ2A |
| 2.319e-02 | -3.76 | mannosyl-oligosaccharide 1,2-alpha-mannosidase activity | molecular function | GO:0004571 | 8 | 4 | 17224 | 2647 |
EDEM2,MAN1B1,MAN1A1,USF3 |
| 2.319e-02 | -3.76 | RNA polymerase I CORE element sequence-specific DNA binding | molecular function | GO:0001164 | 8 | 4 | 17224 | 2647 |
SMARCA4,UBTF,RRN3,BAZ2A |
| 2.319e-02 | -3.76 | negative regulation of viral process | biological process | GO:0048525 | 94 | 22 | 17256 | 2622 |
TRIM8,TRIM11,ILF3,EIF2AK4,TRIM28,ISG15,CCNK,TFAP4,TRIM26,ZNF639,BANF1,PML,STAT1,TARDBP,RNASEL,TRIM32,MAVS,PARP10,ZC3HAV1,IFI16,TRIM14,SRPK2 |
| 2.321e-02 | -3.76 | V$CREB_Q4 | MSigDB lists | V$CREB_Q4 | 257 | 51 | 17377 | 2626 |
CHMP2A,PKP4,CYLD,SARNP,THOC1,NF1,TSC22D3,CDK2AP2,YTHDC2,ALKBH5,AGPAT1,KLF13,CTCF,RAB6A,CNTROB,UBQLN2,ZADH2,SLC25A37,ABHD16A,HNRNPA2B1,SLC31A1,CDC42,INTS7,PPIG,JOSD1,PABPC1,RNF5,ELOVL5,CLCN3,RPRD1A,TMEM39A,ERF,RAB7A,BTAF1,LDHA,C1orf35,WDHD1,DNAJC9,OGDH,TMEM147,CBX3,SRSF1,GNAS,SDHB,HHEX,ORMDL2,RAB24,ZNF367,SOCS4,ATP6V0C,SMAD1 |
| 2.321e-02 | -3.76 | GSE13485_DAY1_VS_DAY3_YF17D_VACCINE_PBMC_DN | MSigDB lists | GSE13485_DAY1_VS_DAY3_YF17D_VACCINE_PBMC_DN | 177 | 37 | 17377 | 2626 |
ZCCHC9,TAP1,XIAP,TATDN3,SLC25A12,IKBIP,SLC25A43,EXT2,FANCL,MRPL50,SLC31A1,RNFT1,GRSF1,GMEB1,FNIP2,GINS1,TXNL1,NCK1,POLK,CRNKL1,CYP20A1,PSMG1,SMC2,AZI2,ISG15,RHEB,CHCHD3,SCARB2,SETD3,STAT1,LMBR1,PRPF4,MBOAT1,ATP6V0E1,SNX14,SMNDC1,RNF114 |
| 2.321e-02 | -3.76 | GSE12366_GC_VS_NAIVE_BCELL_DN | MSigDB lists | GSE12366_GC_VS_NAIVE_BCELL_DN | 177 | 37 | 17377 | 2626 |
ZBTB10,MAX,CAST,HEXB,BTN3A1,CHKB,MAN2B1,NOTCH2,CHD1,HLA-A,CCDC50,SNX18,TOP1MT,TGFB1,ZNF559,ZMYND11,EMP3,DCTD,ESYT1,LY6E,MACF1,PSMB9,APPL1,ARHGAP15,RPSA,MYO1F,HHEX,ZNF862,GALNT2,L3MBTL3,GOLGA8A,STAT1,RBMS1,PLOD3,PARP10,IFI16,CSNK1D |
| 2.326e-02 | -3.76 | KEGG_THYROID_CANCER | MSigDB lists | KEGG_THYROID_CANCER | 29 | 9 | 17377 | 2626 |
NRAS,CCDC6,KRAS,TFG,MAPK1,HRAS,MAP2K2,RXRB,MAPK3 |
| 2.326e-02 | -3.76 | GO_NUCLEOTIDE_EXCISION_REPAIR_PREINCISION_COMPLEX_ASSEMBLY | MSigDB lists | GO_NUCLEOTIDE_EXCISION_REPAIR_PREINCISION_COMPLEX_ASSEMBLY | 29 | 9 | 17377 | 2626 |
RPA2,RBX1,RPS27A,CHD1L,XPA,RAD23B,GTF2H2,DDB1,RPA1 |
| 2.326e-02 | -3.76 | REACTOME_INTRINSIC_PATHWAY_FOR_APOPTOSIS | MSigDB lists | REACTOME_INTRINSIC_PATHWAY_FOR_APOPTOSIS | 29 | 9 | 17377 | 2626 |
BAK1,DYNLL1,TFDP1,XIAP,E2F1,PPP3R1,CYCS,BCL2,BCL2L1 |
| 2.326e-02 | -3.76 | CACGTTT,MIR-302A | MSigDB lists | CACGTTT,MIR-302A | 29 | 9 | 17377 | 2626 |
UCHL5,PARL,LRRC8A,CNNM3,EYA2,PURA,ABHD16A,SRSF10,PRPF4B |
| 2.326e-02 | -3.76 | REACTOME_KERATAN_SULFATE_KERATIN_METABOLISM | MSigDB lists | REACTOME_KERATAN_SULFATE_KERATIN_METABOLISM | 29 | 9 | 17377 | 2626 |
GNS,B4GALT5,HEXB,B4GALT1,ST3GAL2,B4GALT4,B4GALT3,HEXA,B4GALT2 |
| 2.328e-02 | -3.76 | G_patch | smart domains | SM00443 | 21 | 7 | 9493 | 1367 |
RBM17,SUGP1,NKRF,AGGF1,CHERP,SUGP2,GPATCH4 |
| 2.329e-02 | -3.76 | GSE14769_40MIN_VS_360MIN_LPS_BMDM_DN | MSigDB lists | GSE14769_40MIN_VS_360MIN_LPS_BMDM_DN | 194 | 40 | 17377 | 2626 |
SLC30A9,MIF4GD,GPR132,TXN,ANXA6,AGTRAP,RAB11B,DLGAP4,JMJD6,CHAC2,THRAP3,PSEN1,TMEM179B,SLC31A1,RAB21,MED10,SNX18,PPP4R1,PIKFYVE,SLC25A1,VOPP1,ANKLE2,DENND1B,OAF,EZR,ARID1A,CAPZA2,SYVN1,PPFIA3,FOXRED1,DOT1L,LEMD2,TRAM2,KPNA4,ZNF436,AEN,TMEM219,CABIN1,NRBP1,USP53 |
| 2.329e-02 | -3.76 | GSE39820_TGFBETA1_IL6_VS_TGFBETA1_IL6_IL23A_TREATED_CD4_TCELL_UP | MSigDB lists | GSE39820_TGFBETA1_IL6_VS_TGFBETA1_IL6_IL23A_TREATED_CD4_TCELL_UP | 194 | 40 | 17377 | 2626 |
CDS2,CORO7,TMX4,SMC6,ASAH1,CNTROB,ARF1,COPG2,POFUT1,CPNE3,PAIP1,PRKD3,AHCTF1,ZKSCAN1,SIAH1,INTS1,ARHGEF2,NUP153,FNIP2,MGAT5,TMED2,PDPK1,ZDHHC18,BIRC3,KLF10,TUBGCP5,RTF1,KRAS,WDR81,EAF2,BICD2,CBFB,PLEKHF2,MAP3K4,MAGED2,RAB18,CDC16,VCPIP1,ADAM9,TIGD2 |
| 2.329e-02 | -3.76 | GSE17721_CTRL_VS_GARDIQUIMOD_6H_BMDC_UP | MSigDB lists | GSE17721_CTRL_VS_GARDIQUIMOD_6H_BMDC_UP | 194 | 40 | 17377 | 2626 |
WASF2,MANBA,DAP,ANKH,SNX15,HABP4,NUF2,XPR1,TMEM179B,GOLM1,TTC4,CDC25B,CNOT6L,GPX4,PPP3CA,RBM42,ERLIN1,TMEM216,GLO1,GALK2,CHCHD6,ECH1,RXRB,HAUS8,ANKRD10,SGSH,RBM47,ORMDL2,LIMK1,CDCA7L,DCAF11,MDH1,HMGB2,NCOA1,USP11,CDK2,YWHAH,CCNB2,SLC25A39,MYL12B |
| 2.329e-02 | -3.76 | GSE17721_0.5H_VS_24H_POLYIC_BMDC_DN | MSigDB lists | GSE17721_0.5H_VS_24H_POLYIC_BMDC_DN | 194 | 40 | 17377 | 2626 |
TRIP12,THOC1,CHIC2,SECISBP2,THRAP3,UBE2I,TMEM179B,FBRS,FAM192A,SHC1,CAPZA1,ANXA5,MOB1A,MCMBP,DRAM2,ELOF1,ETV3,SNX2,BAZ2A,GALC,ATP2C1,ZNF574,WBP2,RABIF,HTATIP2,ARPC1A,PRDX1,ARF4,DDX17,CCDC127,OSBPL11,KEAP1,PPP2R5A,RBM47,MFAP1,PRPS2,OAZ2,ATP6V1C1,SNX14,STARD3NL |
| 2.333e-02 | -3.76 | RNA stabilization | biological process | GO:0043489 | 43 | 12 | 17256 | 2622 |
SYNCRIP,DHX9,E2F1,AXIN2,CIRBP,TARDBP,YBX1,THRAP3,PARN,MAPK14,PABPC1,PAIP1 |
| 2.333e-02 | -3.76 | plasma membrane invagination | biological process | GO:0099024 | 43 | 12 | 17256 | 2622 |
RHOG,SCARB2,RHOA,CDC42,SH3BP1,SNX18,ELMO1,RAC1,MYH9,AURKB,BECN1,ABCA1 |
| 2.333e-02 | -3.76 | cellular response to inorganic substance | biological process | GO:0071241 | 193 | 40 | 17256 | 2622 |
ADD1,NQO1,PHB2,SLC41A1,PRKAA1,ANK3,MEF2A,CCNB1,BLM,BECN1,CPNE3,PRNP,EEF2K,CFLAR,CCNA2,CLIC4,TIGAR,EIF4A3,DNM2,CDKN1B,TIMELESS,CARF,MOB1A,CREB1,OGG1,SPIDR,CPNE1,PPIF,RHOA,TBRG4,ARID1A,MTR,MAPK3,GUCY1B1,PKD2,FUS,PPP5C,CDK2,MAPK1,XRCC4 |
| 2.335e-02 | -3.76 | microtubule nucleation | biological process | GO:0007020 | 20 | 7 | 17256 | 2622 |
MZT1,NDE1,GOLGA2,CENPJ,TUBGCP2,CSNK1D,TUBGCP5 |
| 2.335e-02 | -3.76 | pyrimidine deoxyribonucleotide metabolic process | biological process | GO:0009219 | 20 | 7 | 17256 | 2622 |
DCTD,OGG1,DUT,HDDC2,NEIL2,MBD4,TBPL1 |
| 2.338e-02 | -3.76 | Interleukin-6 signaling | REACTOME pathways | R-HSA-1059683 | 11 | 5 | 10287 | 1696 |
JAK1,STAT3,IL6ST,STAT1,PTPN11 |
| 2.338e-02 | -3.76 | SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs | REACTOME pathways | R-HSA-77588 | 11 | 5 | 10287 | 1696 |
SLBP,SNRPG,ZNF473,SNRPD3,SNRPB |
| 2.339e-02 | -3.76 | aging | biological process | GO:0007568 | 250 | 50 | 17256 | 2622 |
MIF,GCLM,DNMT3A,NQO1,RWDD1,SMC6,PSEN1,BECN1,MAPK14,FOXO3,APP,PRNP,PTEN,MBD2,MSH2,RPN2,BCL2,CISD2,CREB1,SLC12A2,STAT3,OGG1,MSH6,HTRA2,CARM1,MORC3,TERF2,TGFB1,BAK1,ULK3,ERCC1,TIMP2,ERO1A,AURKB,MBD3,PICALM,SERP1,CAT,IDE,SCAP,NSMCE2,ARNTL,PML,H2AFX,NUP62,CHEK2,ZMIZ1,HRAS,CDKN2A,PDCD4 |
| 2.345e-02 | -3.75 | Rab protein signal transduction | biological process | GO:0032482 | 68 | 17 | 17256 | 2622 |
RAB14,RAB11B,RAB7A,RAB23,RAB6A,RAB1A,RAB5B,IFT27,RAB11A,RAB22A,RAB2B,RAB8A,RAB18,RAB21,RAB24,RAB35,RAB4A |
| 2.349e-02 | -3.75 | HOEBEKE_LYMPHOID_STEM_CELL_UP | MSigDB lists | HOEBEKE_LYMPHOID_STEM_CELL_UP | 84 | 20 | 17377 | 2626 |
RAB14,NCOR2,TNFAIP3,NF1,UBR2,SF3B1,TMEM41B,NACA,MED13L,SMARCA4,MEF2A,MACF1,KDM3A,METTL3,TNS3,CHD3,KNTC1,TRAF5,ABCA1,USP34 |
| 2.349e-02 | -3.75 | KEGG_SMALL_CELL_LUNG_CANCER | MSigDB lists | KEGG_SMALL_CELL_LUNG_CANCER | 84 | 20 | 17377 | 2626 |
MAX,BIRC3,AKT2,XIAP,E2F3,CYCS,BCL2L1,BIRC2,RXRB,RB1,PTEN,PIK3R2,PIAS2,E2F1,ITGB1,CDKN1B,BCL2,CDK2,TRAF5,E2F2 |
| 2.349e-02 | -3.75 | RUAN_RESPONSE_TO_TNF_DN | MSigDB lists | RUAN_RESPONSE_TO_TNF_DN | 84 | 20 | 17377 | 2626 |
MUT,UCK1,PXMP2,ESYT1,RGS2,AP3S1,REEP5,ECH1,CDKN2C,ACOX1,TPP2,HIPK2,DBI,CEBPG,SCARB1,ACADM,TALDO1,TOB1,HIPK3,CBX4 |
| 2.351e-02 | -3.75 | PCGF5 (polycomb group ring finger 5) | protein interactions | 84333 | 36 | 11 | 17029 | 2761 |
PHC2,UBE2D3,TRIM8,EIF4ENIF1,POLK,CSNK2A1,YWHAZ,KIF2C,PCGF1,RYBP,FBRS |
| 2.351e-02 | -3.75 | RAD54B (RAD54 homolog B) | protein interactions | 25788 | 36 | 11 | 17029 | 2761 |
MDM2,PRKAA1,ELOA,PSMA1,GORASP2,GMCL1,FUS,COPS6,UBE2I,CDC23,RAD54B |
| 2.351e-02 | -3.75 | CENPE (centromere protein E) | protein interactions | 1062 | 36 | 11 | 17029 | 2761 |
PCM1,CENPF,LRPPRC,PRC1,CUL1,NUF2,DNAJB1,SEPT7,MAPK1,CBX4,SPTAN1 |
| 2.351e-02 | -3.75 | MRPL43 (mitochondrial ribosomal protein L43) | protein interactions | 84545 | 36 | 11 | 17029 | 2761 |
MRPL50,DDX56,MRPL9,CYLD,NDUFA2,MRPL42,MRPL39,LAMTOR3,MRPL40,ARRB2,CAND1 |
| 2.351e-02 | -3.75 | ATP2B1 (ATPase plasma membrane Ca2+ transporting 1) | protein interactions | 490 | 36 | 11 | 17029 | 2761 |
UNK,ATP1A1,RAB7A,IDH3A,CSNK2A1,ERBIN,TOMM40,ETS1,PRKACA,GNB2,TERF2 |
| 2.351e-02 | -3.75 | NUDT18 (nudix hydrolase 18) | protein interactions | 79873 | 36 | 11 | 17029 | 2761 |
TERF2IP,NAT9,RWDD1,DHPS,DUT,KCTD17,DCTD,CUTC,COIL,RAB3IL1,RAD54B |
| 2.351e-02 | -3.75 | AHI1 (Abelson helper integration site 1) | protein interactions | 54806 | 36 | 11 | 17029 | 2761 |
SRP72,PPP2CA,PCM1,CCDC138,DCTN2,DNM2,SIRT2,DVL1,ECD,DCTN1,HAUS8 |
| 2.351e-02 | -3.75 | ELP2 (elongator acetyltransferase complex subunit 2) | protein interactions | 55250 | 36 | 11 | 17029 | 2761 |
KIF5B,CTDP1,JAK1,STAT1,POLR2D,ELP4,MPG,STAT3,NRBP1,USP34,WRNIP1 |
| 2.351e-02 | -3.75 | MBD1 (methyl-CpG binding domain protein 1) | protein interactions | 4152 | 36 | 11 | 17029 | 2761 |
PCNA,STAT1,PIAS2,KIF2C,RBPJ,MCM2,SMAD1,HIPK3,APP,CBX4,CHAF1A |
| 2.351e-02 | -3.75 | TEC (tec protein tyrosine kinase) | protein interactions | 7006 | 36 | 11 | 17029 | 2761 |
VAV1,GNA12,WAS,PTPN18,SHC1,JAK1,PIK3R2,RAC1,ARHGEF12,LYN,PIP4K2A |
| 2.351e-02 | -3.75 | MEF2C (myocyte enhancer factor 2C) | protein interactions | 4208 | 36 | 11 | 17029 | 2761 |
IFRD1,SMAD2,HDAC7,CSNK2A1,YWHAZ,MEF2A,MEF2D,UBE2I,CCNB1,MAPK14,NCOA2 |
| 2.351e-02 | -3.75 | NDUFV3 (NADH:ubiquinone oxidoreductase subunit V3) | protein interactions | 4731 | 36 | 11 | 17029 | 2761 |
NDUFV2,NDUFV1,NDUFS1,CDC42,TIMMDC1,NDUFA11,ILF3,NDUFS5,DNAJC30,NDUFS7,NDUFS4 |
| 2.351e-02 | -3.75 | TATDN1 (TatD DNase domain containing 1) | protein interactions | 83940 | 36 | 11 | 17029 | 2761 |
CAPN2,PDCD10,GART,PPP1R2,PSPC1,ATIC,HEXB,NSFL1C,PPP5C,UBE2I,ECPAS |
| 2.351e-02 | -3.75 | LIMS1 (LIM zinc finger domain containing 1) | protein interactions | 3987 | 36 | 11 | 17029 | 2761 |
CMAS,MBIP,ASPM,MYO18A,STK11,KIF22,SMURF1,SRRT,REPS1,XRCC5,CDC5L |
| 2.351e-02 | -3.75 | ERCC1 (ERCC excision repair 1, endonuclease non-catalytic subunit) | protein interactions | 2067 | 36 | 11 | 17029 | 2761 |
RPA2,XPA,MSH2,ACAT1,TAF12,TWF2,TAF6,APP,POLR2A,RPA1,CDC5L |
| 2.351e-02 | -3.75 | COMMD3 (COMM domain containing 3) | protein interactions | 23412 | 36 | 11 | 17029 | 2761 |
CCDC93,COMMD10,VPS26C,MIA2,COMMD5,COMMD4,COMMD6,TRAF5,COMMD8,SH3GLB1,VPS29 |
| 2.351e-02 | -3.75 | SMG1 (SMG1, nonsense mediated mRNA decay associated PI3K related kinase) | protein interactions | 23049 | 36 | 11 | 17029 | 2761 |
TELO2,HSPA4,UPF1,EIF4A3,GSPT2,RBM8A,UPF2,RUVBL2,SMG9,PABPC1,HAUS2 |
| 2.353e-02 | -3.75 | Signaling by FGFR in disease | REACTOME pathways | R-HSA-1226099 | 63 | 17 | 10287 | 1696 |
FGFR1OP,POLR2I,NRAS,POLR2G,POLR2L,POLR2K,POLR2D,KRAS,POLR2A,GTF2F1,FGFR3,POLR2J,MYO18A,STAT1,STAT3,HRAS,FGFR1OP2 |
| 2.354e-02 | -3.75 | malignant_peripheral_nerve_sheath_tumour | COSMIC cancer mutations | malignant_peripheral_nerve_sheath_tumour | 39 | 11 | 17385 | 2587 |
FGFR3,RB1,EWSR1,NRAS,NF1,PTEN,ETV6,KRAS,FUS,HRAS,CDKN2A |
| 2.357e-02 | -3.75 | PEA15 (proliferation and apoptosis adaptor protein 15) | protein interactions | 8682 | 23 | 8 | 17029 | 2761 |
TERF2IP,PDPK1,MAPK1,LUC7L2,HTRA2,CAMK2G,FADD,MAPK3 |
| 2.357e-02 | -3.75 | DHRS2 (dehydrogenase/reductase 2) | protein interactions | 10202 | 23 | 8 | 17029 | 2761 |
MDM2,MCM2,AP3S1,PPME1,CDC73,TACC3,GMEB1,SDC2 |
| 2.357e-02 | -3.75 | CCDC97 (coiled-coil domain containing 97) | protein interactions | 90324 | 23 | 8 | 17029 | 2761 |
COPA,MAPK14,SF3B1,SF3A2,TTC33,SF3B6,SRPK2,SF3B2 |
| 2.357e-02 | -3.75 | MYL6B (myosin light chain 6B) | protein interactions | 140465 | 23 | 8 | 17029 | 2761 |
HUWE1,TCF3,RAC1,MYO18A,CUL1,MYH9,CAPZA2,ANLN |
| 2.357e-02 | -3.75 | VAT1 (vesicle amine transport 1) | protein interactions | 10493 | 23 | 8 | 17029 | 2761 |
ZFYVE21,EIF2S2,NRAS,MVP,CDK2,PFKP,H2AFX,TMEM216 |
| 2.357e-02 | -3.75 | CIT (citron rho-interacting serine/threonine kinase) | protein interactions | 11113 | 23 | 8 | 17029 | 2761 |
RPAP3,HGS,CYLD,RHOA,RHOC,RAC1,ANLN,RHOB |
| 2.357e-02 | -3.75 | PRPS2 (phosphoribosyl pyrophosphate synthetase 2) | protein interactions | 5634 | 23 | 8 | 17029 | 2761 |
PRIM2,INPP5A,PRPSAP1,WDYHV1,PRPS2,UBXN1,NMT2,RMC1 |
| 2.357e-02 | -3.75 | GEMIN8 (gem nuclear organelle associated protein 8) | protein interactions | 54960 | 23 | 8 | 17029 | 2761 |
GEMIN5,DDX20,GEMIN6,SNRPG,SNRNP70,APP,STRAP,GEMIN7 |
| 2.357e-02 | -3.75 | CDKN1C (cyclin dependent kinase inhibitor 1C) | protein interactions | 1028 | 23 | 8 | 17029 | 2761 |
RB1,PCNA,CCNA2,RBL1,LIMK1,MYBL2,PIAS2,CDK2 |
| 2.357e-02 | -3.75 | ALAD (aminolevulinate dehydratase) | protein interactions | 210 | 23 | 8 | 17029 | 2761 |
HSPBP1,LAP3,PPME1,WDR4,OGT,CNN2,AGFG1,RPRD1B |
| 2.357e-02 | -3.75 | PPIL4 (peptidylprolyl isomerase like 4) | protein interactions | 85313 | 23 | 8 | 17029 | 2761 |
USP7,JMJD6,XRCC3,FUS,CHERP,PSMD3,RAB3IL1,LUC7L2 |
| 2.357e-02 | -3.75 | F2RL1 (F2R like trypsin receptor 1) | protein interactions | 2150 | 23 | 8 | 17029 | 2761 |
GEMIN6,INTS12,CAPN2,GEMIN4,BIRC5,CAPN1,LMNA,C19orf25 |
| 2.357e-02 | -3.75 | Nek9 (NIMA (never in mitosis gene a)-related expressed kinase 9) | protein interactions | 217718 | 23 | 8 | 17029 | 2761 |
RPA2,NEK7,DYNLL1,DDA1,EML4,TUBB,DDB1,RRP36 |
| 2.357e-02 | -3.75 | ZMAT3 (zinc finger matrin-type 3) | protein interactions | 64393 | 23 | 8 | 17029 | 2761 |
HNRNPA2B1,CNOT6,STAU1,PRKRA,SIAH1,APP,SUMO2,DHX9 |
| 2.357e-02 | -3.75 | CTDSP1 (CTD small phosphatase 1) | protein interactions | 58190 | 23 | 8 | 17029 | 2761 |
FAM118B,TAB2,LDB1,PTPN11,CDCA3,CTDSP2,POLR2A,GTF2F1 |
| 2.357e-02 | -3.75 | NUAK1 (NUAK family kinase 1) | protein interactions | 9891 | 23 | 8 | 17029 | 2761 |
PLK1,PPP1R12A,CASP6,PRKAA1,PPP1R12C,CUL1,PRPSAP1,APP |
| 2.357e-02 | -3.75 | ALDH5A1 (aldehyde dehydrogenase 5 family member A1) | protein interactions | 7915 | 23 | 8 | 17029 | 2761 |
SEC31A,MRPL50,GATC,ARF5,VDAC1,PKM,TOMM40,GLMP |
| 2.357e-02 | -3.75 | LANCL2 (LanC like 2) | protein interactions | 55915 | 23 | 8 | 17029 | 2761 |
TERF2IP,OTUD5,GMFG,MCM2,APP,TCF3,TERF2,MON1B |
| 2.357e-02 | -3.75 | SSH2 (slingshot protein phosphatase 2) | protein interactions | 85464 | 23 | 8 | 17029 | 2761 |
MYH9,ACTB,YWHAZ,CAPZA2,ANLN,LIMK1,CFL1,MYO18A |
| 2.357e-02 | -3.75 | KMT5A (lysine methyltransferase 5A) | protein interactions | 387893 | 23 | 8 | 17029 | 2761 |
DTL,PCNA,RBBP4,UBE2I,E2F2,KMT5A,SUZ12,DDB1 |
| 2.357e-02 | -3.75 | ZNF223 (zinc finger protein 223) | protein interactions | 7766 | 23 | 8 | 17029 | 2761 |
TRIM41,HAUS4,TRIM26,STRIP1,TRIM28,PPM1G,ZNF92,STRN4 |
| 2.357e-02 | -3.75 | RAPGEF1 (Rap guanine nucleotide exchange factor 1) | protein interactions | 2889 | 23 | 8 | 17029 | 2761 |
CRKL,ATXN1,MBIP,RPS15,RAP1A,SHC1,SLC20A1,HRAS |
| 2.357e-02 | -3.75 | RAB21 (RAB21, member RAS oncogene family) | protein interactions | 23011 | 23 | 8 | 17029 | 2761 |
GBA,LAMTOR3,HNRNPF,MCM2,FANCE,APPL1,SDHA,RAB2B |
| 2.357e-02 | -3.75 | ANKRD13D (ankyrin repeat domain 13D) | protein interactions | 338692 | 23 | 8 | 17029 | 2761 |
UBQLN4,TNFAIP3,ERGIC3,WBP2,SMURF1,CTDSP2,APP,CSNK1G3 |
| 2.357e-02 | -3.75 | SURF1 (SURF1, cytochrome c oxidase assembly factor) | protein interactions | 6834 | 23 | 8 | 17029 | 2761 |
NDUFS8,COX15,NDUFV2,CYC1,PTGES3,SRSF5,EDEM2,ABCC1 |
| 2.361e-02 | -3.75 | single thymine insertion binding | molecular function | GO:0032143 | 2 | 2 | 17224 | 2647 |
MSH6,MSH2 |
| 2.361e-02 | -3.75 | electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity | molecular function | GO:0045155 | 2 | 2 | 17224 | 2647 |
CYCS,CYC1 |
| 2.361e-02 | -3.75 | rRNA (cytosine-C5-)-methyltransferase activity | molecular function | GO:0009383 | 2 | 2 | 17224 | 2647 |
NOP2,NSUN4 |
| 2.361e-02 | -3.75 | non-sequence-specific DNA binding, bending | molecular function | GO:0044378 | 2 | 2 | 17224 | 2647 |
HMGB2,SAP30L |
| 2.361e-02 | -3.75 | 5.8S rRNA binding | molecular function | GO:1990932 | 2 | 2 | 17224 | 2647 |
RPL19,RPL8 |
| 2.361e-02 | -3.75 | mRNA cap binding | molecular function | GO:0098808 | 2 | 2 | 17224 | 2647 |
EIF3D,AGO2 |
| 2.361e-02 | -3.75 | pyrimidine nucleotide transmembrane transporter activity | molecular function | GO:0015218 | 2 | 2 | 17224 | 2647 |
SLC25A33,SLC25A36 |
| 2.361e-02 | -3.75 | choline kinase activity | molecular function | GO:0004103 | 2 | 2 | 17224 | 2647 |
CHKB,CHKA |
| 2.361e-02 | -3.75 | glutamine-tRNA ligase activity | molecular function | GO:0004819 | 2 | 2 | 17224 | 2647 |
LARS,QARS |
| 2.361e-02 | -3.75 | succinate-CoA ligase (GDP-forming) activity | molecular function | GO:0004776 | 2 | 2 | 17224 | 2647 |
SUCLG2,SUCLG1 |
| 2.361e-02 | -3.75 | tRNA-4-demethylwyosine synthase activity | molecular function | GO:0102521 | 2 | 2 | 17224 | 2647 |
TYW1,TYW1B |
| 2.361e-02 | -3.75 | bisphosphoglycerate phosphatase activity | molecular function | GO:0034416 | 2 | 2 | 17224 | 2647 |
MINPP1,TIGAR |
| 2.361e-02 | -3.75 | coproporphyrinogen oxidase activity | molecular function | GO:0004109 | 2 | 2 | 17224 | 2647 |
RSAD1,CPOX |
| 2.361e-02 | -3.75 | CAAX-protein geranylgeranyltransferase activity | molecular function | GO:0004662 | 2 | 2 | 17224 | 2647 |
FNTA,PGGT1B |
| 2.361e-02 | -3.75 | rRNA (uridine-2'-O-)-methyltransferase activity | molecular function | GO:0008650 | 2 | 2 | 17224 | 2647 |
FTSJ3,MRM2 |
| 2.361e-02 | -3.75 | eukaryotic initiation factor eIF2 binding | molecular function | GO:0071074 | 2 | 2 | 17224 | 2647 |
EIF5,NCK1 |
| 2.361e-02 | -3.75 | N-acylneuraminate cytidylyltransferase activity | molecular function | GO:0008781 | 2 | 2 | 17224 | 2647 |
CMAS,NANS |
| 2.361e-02 | -3.75 | inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity | molecular function | GO:0051717 | 2 | 2 | 17224 | 2647 |
MINPP1,PTEN |
| 2.361e-02 | -3.75 | isoleucine-tRNA ligase activity | molecular function | GO:0004822 | 2 | 2 | 17224 | 2647 |
IARS,IARS2 |
| 2.361e-02 | -3.75 | galactokinase activity | molecular function | GO:0004335 | 2 | 2 | 17224 | 2647 |
GALK1,GALK2 |
| 2.361e-02 | -3.75 | tRNA (guanine-N7-)-methyltransferase activity | molecular function | GO:0008176 | 2 | 2 | 17224 | 2647 |
METTL1,WDR4 |
| 2.366e-02 | -3.74 | EIF5 (eukaryotic translation initiation factor 5) | protein interactions | 1983 | 64 | 17 | 17029 | 2761 |
RPL29,EIF3D,CSNK2A1,EIF4H,EIF4G2,EIF3G,BZW2,APP,LMNA,MAT2B,EIF2S2,HUWE1,DDA1,YWHAZ,PCYT2,YWHAH,TUBB |
| 2.366e-02 | -3.74 | SYDE1 (synapse defective Rho GTPase homolog 1) | protein interactions | 85360 | 64 | 17 | 17029 | 2761 |
POLR2I,NF1,FAM53C,DENND4C,POLR2D,RAB3IP,USP21,GIGYF1,POLR2A,EDC3,RTKN,AFDN,ZBTB21,POLR2J,FAM110A,KIF13B,CDC25B |
| 2.366e-02 | -3.74 | HIP1R (huntingtin interacting protein 1 related) | protein interactions | 9026 | 64 | 17 | 17029 | 2761 |
SLC39A9,EWSR1,PSPC1,DYNLL1,TUFM,MYH9,MTMR6,CAPZA2,AP1B1,REPS1,PICALM,CRKL,GART,GTSE1,CLTB,TATDN1,CDC5L |
| 2.366e-02 | -3.74 | PDLIM5 (PDZ and LIM domain 5) | protein interactions | 10611 | 64 | 17 | 17029 | 2761 |
METTL1,DNAJC8,EIF4A3,TULP3,SUZ12,RAD23B,ANP32A,ARFIP2,ACTB,NFATC2IP,BRCA1,NDUFA7,PKM,COIL,MAP2K2,NPLOC4,CAMK2G |
| 2.366e-02 | -3.74 | KIF1B (kinesin family member 1B) | protein interactions | 23095 | 64 | 17 | 17029 | 2761 |
GOPC,SMC6,BRCA1,UBE2I,APP,GIGYF1,RTKN,ZBTB21,VPS26B,SIAH1,KIF13B,PPP4R1,VIPAS39,ECPAS,YWHAH,CHP1,PDF |
| 2.366e-02 | -3.74 | GPS2 (G protein pathway suppressor 2) | protein interactions | 2874 | 64 | 17 | 17029 | 2761 |
GID8,RMND5A,NCOR2,MKLN1,FOXK1,MAP3K7CL,SESTD1,PBK,PPFIA3,SPDL1,ARMC8,DAPK3,MAPK3,GOLGA2,GPS2,CHD3,CREB1 |
| 2.366e-02 | -3.74 | PTPA (protein phosphatase 2 phosphatase activator) | protein interactions | 5524 | 64 | 17 | 17029 | 2761 |
SP3,CCT2,CYLD,MYH9,CSNK2A1,RACGAP1,AURKB,FOXO3,CCT8,APP,MARK2,PPP2CA,MDM2,PTEN,H2AFX,STAT1,ARRB2 |
| 2.366e-02 | -3.74 | LZTR1 (leucine zipper like transcription regulator 1) | protein interactions | 8216 | 64 | 17 | 17029 | 2761 |
LZTR1,AATF,SUGP2,EHMT1,CUL3,MYBL2,RIT1,SND1,TCF19,CHAF1A,SP100,L3MBTL3,EIF4A3,STAT1,POLR1B,CNOT6L,IFI16 |
| 2.366e-02 | -3.74 | GO_PROTEIN_SERINE_THREONINE_KINASE_ACTIVITY | MSigDB lists | GO_PROTEIN_SERINE_THREONINE_KINASE_ACTIVITY | 428 | 80 | 17377 | 2626 |
CCNC,PRKAB1,TP53RK,RPS6KA1,RAF1,SNX15,CSNK2A1,CCNB1,PRKACA,MAPK14,CPNE3,EEF2K,CDK5,PRKD3,NEK6,MAST2,CDK12,SRPK2,PLK3,PLK1,ULK3,AKT2,PBK,TLK1,MAP4K4,TAOK1,AURKB,PKMYT1,STK17B,MAP3K4,MKNK1,CLK3,LIMK1,STK38,FASTK,HIPK2,CAB39,STK11,CHEK2,ROCK1,MAPK1,CSNK1D,PRPF4B,TRIO,PRKAA1,ADCK5,CDK13,EIF2AK4,CDK11B,CSNK1A1,CCNK,DAPK1,MAP3K14,GTF2H2,PHKG2,CAMK2G,CSNK1G3,PDPK1,CSNK1G2,MAPKAPK3,NEK7,PRKDC,EIF2AK1,MAP4K3,MARK2,MAP2K2,CDK11A,DAPK3,MAPK3,MASTL,NEK1,LTBP4,CSNK1G1,MAPK6,MAP3K5,CDK2,RPS6KC1,CCNB2,NRBP1,HIPK3 |
| 2.368e-02 | -3.74 | GSE37532_WT_VS_PPARG_KO_LN_TREG_UP | MSigDB lists | GSE37532_WT_VS_PPARG_KO_LN_TREG_UP | 166 | 35 | 17377 | 2626 |
MBD1,GLT8D1,SRGN,UCK2,PLAGL2,PPP1R16B,ARID1B,MXD1,NDUFS7,CCNK,EIF4A3,LRRC8D,ETV6,FEM1B,UPRT,CITED2,FAM3A,ULK3,ARHGAP17,BRD4,PSMA1,WIPF1,ATP6V0A1,LNX2,UHRF1BP1,USP21,RAB2B,ANKRD10,CAT,TRAM2,GOLGA2,HIPK2,PML,TAF6,ABCA1 |
| 2.368e-02 | -3.74 | Clathrin_app_Ig-like_sf | interpro domains | IPR013041 | 12 | 5 | 18492 | 2768 |
AP2B1,AP1B1,GGA2,GGA1,COPG2 |
| 2.372e-02 | -3.74 | V$STAT_Q6 | MSigDB lists | V$STAT_Q6 | 240 | 48 | 17377 | 2626 |
COX5B,PDCD6IP,GOLPH3L,SCAMP3,EYA1,EIF3D,ANK3,SNX15,UBE2Z,ARFIP2,SMC6,HCFC1R1,XPR1,CREM,IRF4,ADD3,NEK6,SLC38A5,TNPO3,ZFYVE27,ZRANB1,ABCC5,PPP1R9B,AATF,PGGT1B,TLK1,CAMSAP1,SREK1,RFFL,TOPORS,UBE4B,ARPC1A,ARMC8,ALKBH6,ZMYM3,IWS1,C1orf122,PI4K2A,SEC31A,ZNF180,TSC1,ORMDL2,ELMO1,PSMD3,CLU,ROCK1,GEN1,ATXN7L2 |
| 2.375e-02 | -3.74 | ZnF_Rad18 | smart domains | SM00734 | 5 | 3 | 9493 | 1367 |
RAD18,POLK,WRNIP1 |
| 2.375e-02 | -3.74 | EFG_C | smart domains | SM00838 | 5 | 3 | 9493 | 1367 |
EFL1,GFM2,EFTUD2 |
| 2.375e-02 | -3.74 | DZF | smart domains | SM00572 | 5 | 3 | 9493 | 1367 |
STRBP,ZFR,ILF3 |
| 2.375e-02 | -3.74 | NAC | smart domains | SM01407 | 5 | 3 | 9493 | 1367 |
BTF3,NACA,BTF3L4 |
| 2.379e-02 | -3.74 | PIAS1 (protein inhibitor of activated STAT 1) | protein interactions | 8554 | 124 | 29 | 17029 | 2761 |
MBD1,SP3,ZNF76,DNMT3A,POLK,ZMYND11,SUMO2,KLC1,CSNK2A1,ATXN1,BRCA1,UBE2I,SRSF1,MDM2,SIAH1,SAFB,AXIN1,STAT1,PML,SIAH2,PIAS2,YWHAZ,DDX5,CREB1,NR2F2,SMAD1,MAML1,SMAD4,TERF2 |
| 2.383e-02 | -3.74 | vesicle cytoskeletal trafficking | biological process | GO:0099518 | 48 | 13 | 17256 | 2622 |
KIF5B,KIF3B,AP3S2,TRAK1,AP3M2,KIF23,KIFAP3,NDE1,RAB1A,CLN3,AP3S1,MYO5A,SNAPIN |
| 2.389e-02 | -3.73 | GSE17721_CPG_VS_GARDIQUIMOD_24H_BMDC_DN | MSigDB lists | GSE17721_CPG_VS_GARDIQUIMOD_24H_BMDC_DN | 183 | 38 | 17377 | 2626 |
TMED7,GOLIM4,TXN,DEPDC1,RAC1,FKBP2,RGS2,CUTC,FAM8A1,RNF103,SEC11A,SLC31A1,RAP1A,DPYSL2,DAD1,RAD23B,RP2,POLR1B,FAM76B,TECR,OSTC,ALDH18A1,NSUN4,NET1,ADSL,ATXN1,CCDC34,DTWD1,TPD52L2,CDC16,FNTA,SNAP23,SOCS4,CHMP4B,SLAIN1,PKD2,GAS2,ZNF146 |
| 2.389e-02 | -3.73 | GSE6875_WT_VS_FOXP3_KO_TREG_DN | MSigDB lists | GSE6875_WT_VS_FOXP3_KO_TREG_DN | 183 | 38 | 17377 | 2626 |
PIGN,AGTRAP,NENF,MXD4,USP48,ITGB5,IFT27,MFSD10,EPM2A,CAPN2,ZBTB45,TNS3,ASAP2,BCAP29,ACAD8,FAM172A,LONRF3,PBK,SREK1,MIER2,DCTD,AURKB,CCNF,GUF1,PRPSAP1,SRSF1,TMEM41A,WDR11,RBM47,BIRC5,TFDP1,E2F1,QRSL1,PDXK,RUFY3,CD81,ZMAT3,GCSH |
| 2.389e-02 | -3.73 | GSE3203_UNTREATED_VS_IFNB_TREATED_LN_BCELL_UP | MSigDB lists | GSE3203_UNTREATED_VS_IFNB_TREATED_LN_BCELL_UP | 183 | 38 | 17377 | 2626 |
SLC30A9,TMED7,TMEM41B,CHD1L,SCYL1,PRKAA1,NDUFA4,DUSP22,ARL6IP6,MAN1A1,SLC31A1,IL6ST,JAZF1,LPIN2,MDFIC,PIKFYVE,LRSAM1,HDHD2,TPCN1,ZNF583,PDCL3,USO1,NSDHL,GOPC,NARF,NFATC2IP,SLC17A5,RIT1,EAF2,DCLRE1C,SERP1,CCDC127,TAF2,ZNF180,L3MBTL3,OSBPL8,KBTBD7,ATE1 |
| 2.389e-02 | -3.73 | GSE11924_TFH_VS_TH1_CD4_TCELL_DN | MSigDB lists | GSE11924_TFH_VS_TH1_CD4_TCELL_DN | 183 | 38 | 17377 | 2626 |
SEPHS2,GOLIM4,GNPNAT1,NOP2,MRPS2,RAE1,DNAJC24,HAUS4,GYG1,SNRPD3,PCNA,EXOSC1,MRPS27,SOCS6,NSFL1C,NOC2L,ACSL5,SRP72,LAP3,PPIE,RDH10,SLC16A7,RPL6,BICD2,CADM1,RAB1A,MBD3,CCT8,TRIM28,ORMDL2,AP1S1,PRPF4,TAF12,COPS6,REEP4,VPS29,TUBB,ZNF511 |
| 2.389e-02 | -3.73 | GSE8621_UNSTIM_VS_LPS_STIM_MACROPHAGE_DN | MSigDB lists | GSE8621_UNSTIM_VS_LPS_STIM_MACROPHAGE_DN | 183 | 38 | 17377 | 2626 |
RHOG,FAM129A,COPE,HEXB,AGPAT3,CDK11B,SLC20A1,MIEN1,FAM8A1,RRP36,SEC11A,NUP210,PPCDC,RNF19A,STAT3,USP34,POU2AF1,NEK7,TEX10,GBA,AZI2,HERPUD2,KRIT1,BRMS1,PLD3,OSBPL11,PPP2R5A,DDOST,TPP2,CSNK1G1,WDR59,STAT1,ACLY,C7orf26,VPS29,HIGD2A,CAPN1,RNF114 |
| 2.389e-02 | -3.73 | GSE2128_C57BL6_VS_NOD_THYMOCYTE_MIMETOPE_NEGATIVE_SELECTION_DN | MSigDB lists | GSE2128_C57BL6_VS_NOD_THYMOCYTE_MIMETOPE_NEGATIVE_SELECTION_DN | 183 | 38 | 17377 | 2626 |
WSB2,NF1,PPP1R15B,B4GALT5,MECP2,RPL15,RBM17,ERH,PSMA6,TANK,RAD23B,FOXN2,CISD2,MINPP1,CITED2,TRIM14,IMPA2,DRAM2,ACSL5,GTF3C6,ADAM17,COQ10B,BCLAF1,EIF4G2,STK17B,SERP1,CYB5A,ECH1,CAT,UTP20,INF2,NAGLU,KBTBD7,SIAH2,MEGF9,BTBD10,PDLIM5,SMNDC1 |
| 2.389e-02 | -3.73 | GSE17721_12H_VS_24H_POLYIC_BMDC_UP | MSigDB lists | GSE17721_12H_VS_24H_POLYIC_BMDC_UP | 183 | 38 | 17377 | 2626 |
ANXA6,DHPS,SLC41A1,AP3M2,LAMTOR3,PCSK7,SLC12A9,SUB1,ARF5,DDA1,TPST1,FOXN2,TRA2B,AFF1,NDUFS8,RBM3,TFG,MINPP1,SEH1L,MORC3,LDHB,SAMD4B,TIMP2,CSRP1,NCK1,ILF3,SLC25A22,NUSAP1,RAB22A,RHOB,SMAD2,GADD45B,SEL1L,NR2F2,CD81,TRAF5,TOB1,S100PBP |
| 2.389e-02 | -3.73 | GSE7460_TREG_VS_TCONV_ACT_UP | MSigDB lists | GSE7460_TREG_VS_TCONV_ACT_UP | 183 | 38 | 17377 | 2626 |
DYNLL1,CIB1,CERK,NDUFA4,HMGN3,GMCL1,TMED3,BCL2L1,BECN1,LYN,POFUT1,CDC73,MXD1,RGS1,UBLCP1,RB1,LRRC8D,RABGAP1L,PPIG,SLC44A1,TANK,ANKRD13C,CLDND1,CENPM,N4BP2,TNFAIP3,KRAS,DIDO1,GOSR1,ALKBH6,CERS6,TAB2,SNAP23,HIPK2,KLHL15,STAT1,PTAR1,DDX5 |
| 2.389e-02 | -3.73 | GSE5589_WT_VS_IL10_KO_LPS_STIM_MACROPHAGE_45MIN_DN | MSigDB lists | GSE5589_WT_VS_IL10_KO_LPS_STIM_MACROPHAGE_45MIN_DN | 183 | 38 | 17377 | 2626 |
WSB2,TRIP12,MRI1,CSNK1A1,PCYOX1L,KRI1,NUDT19,TMEM69,SIAH1,UTP18,HDAC7,IL6ST,ZCCHC2,HADHB,COPS7B,TTC17,CCAR1,VOPP1,CDKN2AIP,ERMP1,GABPA,NLN,ABHD11,GALNT7,TTC33,BTBD1,TWISTNB,HSPA1B,AKAP1,ALDH3B1,PDCD6,GOLGA7,SPATA2,PRDX3,PGRMC1,MAPK1,CHMP7,TMEM33 |
| 2.389e-02 | -3.73 | GSE6674_ANTI_IGM_VS_ANTI_IGM_AND_CPG_STIM_BCELL_UP | MSigDB lists | GSE6674_ANTI_IGM_VS_ANTI_IGM_AND_CPG_STIM_BCELL_UP | 183 | 38 | 17377 | 2626 |
MBD1,GLT8D1,MRPL9,CYLD,UROD,HEXB,TAP1,MAP1LC3B,COMMD8,PIP4K2A,CCDC28A,PRPF18,SNRNP25,ADD3,TTC9C,ABCD1,FRMD8,RB1CC1,KIAA0040,PBXIP1,TLK1,POLR3GL,PTTG1IP,NDRG3,FAS,CAT,TSC1,PPP2R5A,TXNDC16,STK38,DCAF11,ZNF436,PSAP,CENPT,NGLY1,GLCCI1,RTN3,ESYT2 |
| 2.391e-02 | -3.73 | Prolactin Signaling Pathway | WikiPathways | WP2037 | 76 | 19 | 5312 | 837 |
PPIB,RAF1,RAC1,VAV2,ELK1,MAPK14,MAP2K2,MAPK3,VAV1,SHC1,JAK1,PIK3R2,ITGB1,STAT1,PTPN11,YWHAZ,STAT3,MAPK1,HRAS |
| 2.391e-02 | -3.73 | Role of Calcineurin-dependent NFAT signaling in lymphocytes | Pathway Interaction DB | nfat_3pathway | 51 | 16 | 2226 | 426 |
CSNK2A1,NFATC2,MEF2D,CSNK1A1,PRKACA,MAPK14,MAPK3,CALM2,FKBP1A,NFATC3,CABIN1,BCL2,KPNA2,YWHAZ,YWHAH,CHP1 |
| 2.395e-02 | -3.73 | cytoplasmic side of plasma membrane | cellular component | GO:0009898 | 175 | 36 | 18223 | 2701 |
PKP4,CYLD,NF1,RACGAP1,RGS2,LYN,MIEN1,BIRC2,RGS1,ABL2,RAB21,ATP2A2,PTEN,SNX18,GNAI2,GM2A,S100A6,KCNAB2,HTRA2,PPP3CA,CYTH1,RHOA,GNG7,EZR,KRAS,MAP2K2,EPB41,GNAS,GNA12,CHMP4A,JAK1,CSK,PTPN7,CHMP4B,TRAF5,ESYT2 |
| 2.395e-02 | -3.73 | Negative regulation of MAPK pathway | REACTOME pathways | R-HSA-5675221 | 40 | 12 | 10287 | 1696 |
PPP2CA,NRAS,PPP2R5A,RPS27A,RAF1,BRAP,KRAS,PPP5C,MAPK1,HRAS,MAP2K2,MAPK3 |
| 2.395e-02 | -3.73 | Presynaptic phase of homologous DNA pairing and strand exchange | REACTOME pathways | R-HSA-5693616 | 40 | 12 | 10287 | 1696 |
RPA2,RAD51C,RFC3,XRCC2,RMI2,TOP3A,BRCA1,BLM,RFC2,RMI1,RAD51D,RPA1 |
| 2.397e-02 | -3.73 | Pathways Affected in Adenoid Cystic Carcinoma | WikiPathways | WP3651 | 66 | 17 | 5312 | 837 |
MAX,PRKDC,RAF1,TLK1,ERBIN,BRCA1,ARID1A,KMT2C,MAP2K2,FOXO3,PTEN,CMTR2,DTX4,CHEK2,MYBL1,SMARCE1,HRAS |
| 2.399e-02 | -3.73 | regulation of viral genome replication | biological process | GO:0045069 | 89 | 21 | 17256 | 2622 |
PPIB,STAU1,YTHDC2,PPIE,ILF3,EIF2AK4,TRIM28,ISG15,RAD23A,CCNK,BANF1,BCL2,DDX5,RNASEL,MAVS,PARP10,PABPC1,DDB1,ZC3HAV1,IFI16,SRPK2 |
| 2.399e-02 | -3.73 | UQ_con | pfam domains | PF00179 | 39 | 11 | 17054 | 2545 |
UBE2D3,UBE2Q2,UBE2E2,UBE2Z,UBE2Q1,KRAS,UBE2V1,UBE2I,UBE2C,UBE2M,UBE2QL1 |
| 2.401e-02 | -3.73 | Autophagy - other | KEGG pathways | hsa04136 | 32 | 10 | 7161 | 1149 |
PPP2CA,ATG9A,ATG3,ATG2B,ATG13,WIPI2,BECN1,IGBP1,ATG4A,MLST8 |
| 2.401e-02 | -3.73 | Autophagy - other | KEGG pathways | ko04136 | 32 | 10 | 7161 | 1149 |
PPP2CA,ATG9A,ATG3,ATG2B,ATG13,WIPI2,BECN1,IGBP1,ATG4A,MLST8 |
| 2.403e-02 | -3.73 | regulation of cell aging | biological process | GO:0090342 | 53 | 14 | 17256 | 2622 |
BCL2L12,MIF,NEK6,CGAS,FOXM1,RBL1,PTEN,PRKDC,ARNTL,PAWR,KRAS,CDKN2A,LMNA,TERF2 |
| 2.403e-02 | -3.73 | 'de novo' protein folding | biological process | GO:0006458 | 53 | 14 | 17256 | 2622 |
FKBP1A,DNAJC2,HSPH1,CCT2,HSPA4,ST13,ERO1A,ZFYVE21,DNAJB1,PTGES3,PIKFYVE,CCT8,BBS12,HSPA1B |
| 2.403e-02 | -3.73 | nucleotide-excision repair, preincision complex assembly | biological process | GO:0006294 | 29 | 9 | 17256 | 2622 |
RPA2,RBX1,RPS27A,XPA,RAD23B,CHD1L,GTF2H2,DDB1,RPA1 |
| 2.403e-02 | -3.73 | regulation of defense response to virus by virus | biological process | GO:0050690 | 29 | 9 | 17256 | 2622 |
AP1S1,AP2B1,PACS1,ARF1,AP1B1,ELMO1,AP2S1,RAC1,AP1M1 |
| 2.406e-02 | -3.73 | GSE37605_C57BL6_VS_NOD_FOXP3_FUSION_GFP_TCONV_UP | MSigDB lists | GSE37605_C57BL6_VS_NOD_FOXP3_FUSION_GFP_TCONV_UP | 155 | 33 | 17377 | 2626 |
HIVEP3,NF1,CHTF18,TOR3A,SUMO2,PLAGL2,CLCC1,BCL2L1,LCLAT1,TMEM165,GFM2,REPS1,ITGB8,JAZF1,TANK,NSFL1C,EI24,YBX1,COPS7B,SLC12A2,TMEM9,SLC35A1,ANKLE2,METTL1,LAP3,SEPT7,TSR2,HMGN2,CHCHD3,RBPJ,SPCS3,CD81,IGBP1 |
| 2.407e-02 | -3.73 | negative regulation of cellular protein localization | biological process | GO:1903828 | 105 | 24 | 17256 | 2622 |
TGFB1,HSPH1,TXN,GOPC,CDT1,RAB23,RANGAP1,BCL2L1,DNAJA1,PICALM,PARK7,SAPCD2,CDK5,SP100,PPP2R5A,CSK,H2AFY,MDFIC,LMAN1,TERF1,TMBIM1,NUMB,SVIP,CHP1 |
| 2.407e-02 | -3.73 | negative regulation of extrinsic apoptotic signaling pathway | biological process | GO:2001237 | 105 | 24 | 17256 | 2622 |
GCLM,TNFAIP3,RB1CC1,ZMYND11,RAF1,EYA1,RFFL,MCL1,BCL2L1,BRCA1,PARK7,FADD,LMNA,FAS,CFLAR,HSPA1B,DAPK1,SIAH2,ARHGEF2,BCL2,HMGB2,EYA2,TMBIM1,ZC3HC1 |
| 2.409e-02 | -3.73 | negative regulation of cellular biosynthetic process | biological process | GO:0031327 | 1563 | 265 | 17256 | 2622 |
TXN,ZNF496,MAX,H2AFZ,KDM4A,TSC22D3,YTHDF3,UBE2I,RBM4,CDK5,PA2G4,CIPC,CRY2,FNIP2,SMARCE1,DNMT1,PLK3,KLF10,AATF,GABPA,EHMT1,DDX20,AURKB,DOT1L,BRMS1,HHEX,SMAD2,RPS27A,RPS14,AXIN1,PRDX5,TFDP2,HDAC2,PDCD4,PRKAA1,EIF2AK4,PSEN1,METTL3,CDC73,CNOT3,TFAP4,SMC3,MEX3C,KLF16,HDAC7,PHF14,DAPK1,GNAI2,LPCAT1,TNRC18,TERF2,ETV3,FOXK1,ZMYND11,MTA2,GTPBP4,ITM2A,BCLAF1,ARID1A,CBFA2T2,FXR1,PHF6,XRCC5,EPRS,PFDN5,ETS2,QARS,YY1,ZNF830,CDK2,RNF139,CDKN2A,EGLN1,ZNF296,DNMT3A,SUZ12,UBR2,MAGED1,WDTC1,RCOR3,PAIP2,SPINDOC,SHC1,SP100,MTA1,CDKN1B,ATF2,RBM15,CGGBP1,SAP30,ERF,EID1,DRAP1,CIRBP,CUL3,H2AFV,TRIM28,CHCHD3,ZNF282,HIPK2,H2AFX,STAT1,BEND3,LRP8,NCOR2,DEPDC1,MECP2,TCF3,BLM,HMG20A,FOXO3,MAD2L2,WWP2,SUV39H2,CITED2,CNOT6L,CREB1,NCOA2,TSHZ1,ILF3,ZP3,CBX3,GPS2,ZHX1,PITX1,PML,KHSRP,HMGB2,DDX5,IGBP1,CPEB2,PURA,RORB,TRIM11,SIRT2,CREM,GLIS2,EIF4A3,JAZF1,METTL14,ZNF639,ETV6,NOC2L,ARID4A,CCAR1,PTPRK,RYBP,SP3,PLK1,DEAF1,BAZ2A,NCK1,PBXIP1,VHL,RIOX2,EZR,CDC6,BRCA1,PAF1,EIF4ENIF1,TONSL,ZNF268,CHEK2,BEND6,POT1,ZNF564,UBE2D3,PHB2,CENPF,TIA1,CTCF,MEF2A,DNAJB1,TTF1,LYAR,RB1,NFATC3,MLX,TIGAR,MBD2,ZNF746,TIMELESS,CTR9,YBX1,MDFIC,MCPH1,ZNF189,CREG1,CIC,ERLIN1,LDB1,RTF1,EIF2AK1,ZNF174,DAPK3,TSC1,ORMDL2,SYNCRIP,NFIL3,SIAH2,ZFP90,RUVBL2,TOB1,N4BP2L2,MBD1,MPHOSPH8,FOXM1,SMARCA4,IRF3,DUSP22,MXD1,SAP130,HNRNPA2B1,ZBTB21,MDM2,STRAP,MOSPD1,RLIM,FAM172A,ZNF500,BTG2,PCGF6,ATXN1,NFATC2,MBD3,ATP1A1,HNRNPR,RBL1,STAT6,MAFK,ARNTL,DNAJC17,H3F3A,SMAD4,CBX4,UNK,DNAJC2,DAP,AGO2,ARID5A,NKRF,PAWR,MXD4,PTPN2,KMT5A,BRD7,H2AFY,STAT3,RBM15B,SAMD4B,TGFB1,ZNF202,PSPC1,BTAF1,RCOR1,MEN1,PRMT2,CNOT9,UPF1,BIRC5,E2F1,RBPJ,NR2F2,TERF1,IFI16 |
| 2.409e-02 | -3.73 | ZHX2 (zinc fingers and homeoboxes 2) | protein interactions | 22882 | 15 | 6 | 17029 | 2761 |
NAGPA,ATXN1,YWHAZ,ZHX1,APP,HRAS |
| 2.409e-02 | -3.73 | ZNF423 (zinc finger protein 423) | protein interactions | 23090 | 15 | 6 | 17029 | 2761 |
USP7,BRCA1,SMAD1,LYN,SMAD4,MTA1 |
| 2.409e-02 | -3.73 | GPX1 (glutathione peroxidase 1) | protein interactions | 2876 | 15 | 6 | 17029 | 2761 |
ABL2,KARS,TXN,CENPJ,MAPK6,DCTN1 |
| 2.409e-02 | -3.73 | GON7 (GON7, KEOPS complex subunit) | protein interactions | 84520 | 15 | 6 | 17029 | 2761 |
TP53RK,HSPBP1,ARPC1A,PPME1,LAGE3,OGT |
| 2.409e-02 | -3.73 | DCUN1D2 (defective in cullin neddylation 1 domain containing 2) | protein interactions | 55208 | 15 | 6 | 17029 | 2761 |
CUL1,RBX1,UBE2M,APP,CAND1,CUL3 |
| 2.409e-02 | -3.73 | P2RX1 (purinergic receptor P2X 1) | protein interactions | 5023 | 15 | 6 | 17029 | 2761 |
ATE1,RAB21,GMCL1,GOLPH3L,PI4K2A,FDFT1 |
| 2.409e-02 | -3.73 | IRGC (immunity related GTPase cinema) | protein interactions | 56269 | 15 | 6 | 17029 | 2761 |
RHOA,AP3S1,RPS6KA1,APP,SLC26A6,PI4K2A |
| 2.409e-02 | -3.73 | RARRES3 (retinoic acid receptor responder 3) | protein interactions | 5920 | 15 | 6 | 17029 | 2761 |
MAVS,CYLD,TNFAIP3,RNF135,UBE2I,HRAS |
| 2.409e-02 | -3.73 | ZNF473 (zinc finger protein 473) | protein interactions | 25888 | 15 | 6 | 17029 | 2761 |
SLBP,AEN,TRIM41,ZNF202,DHX57,RNPS1 |
| 2.409e-02 | -3.73 | Dynlrb1 (dynein light chain roadblock-type 1) | protein interactions | 67068 | 15 | 6 | 17029 | 2761 |
RANGAP1,LUC7L,UBR2,DYNC1LI2,DCTN2,DCTN1 |
| 2.409e-02 | -3.73 | ZNF488 (zinc finger protein 488) | protein interactions | 118738 | 15 | 6 | 17029 | 2761 |
ATXN1,USO1,GOLGA2,GOPC,MAGED1,CAMK2G |
| 2.409e-02 | -3.73 | ZNF800 (zinc finger protein 800) | protein interactions | 168850 | 15 | 6 | 17029 | 2761 |
CNTROB,TM9SF4,DGCR8,MBD3,MTA2,MECP2 |
| 2.409e-02 | -3.73 | NHS (NHS actin remodeling regulator) | protein interactions | 4810 | 15 | 6 | 17029 | 2761 |
KIF5B,RPN1,SYNCRIP,YWHAH,ABI1,CENPU |
| 2.409e-02 | -3.73 | NAA38 (N(alpha)-acetyltransferase 38, NatC auxiliary subunit) | protein interactions | 84316 | 15 | 6 | 17029 | 2761 |
AFDN,API5,LSM6,EIF2D,N4BP2L2,LRPPRC |
| 2.409e-02 | -3.73 | SEPT12 (septin 12) | protein interactions | 124404 | 15 | 6 | 17029 | 2761 |
SEPT8,SEPT11,SEPT1,SEPT7,APP,PDS5B |
| 2.409e-02 | -3.73 | BCAP29 (B cell receptor associated protein 29) | protein interactions | 55973 | 15 | 6 | 17029 | 2761 |
RPN1,COX4I1,LMAN1,VDAC1,PDXDC1,BCAP31 |
| 2.409e-02 | -3.73 | NDUFAF2 (NADH:ubiquinone oxidoreductase complex assembly factor 2) | protein interactions | 91942 | 15 | 6 | 17029 | 2761 |
RPS24,PPIF,NDUFA4,ATXN3,RPS26,SUGP2 |
| 2.409e-02 | -3.73 | NUDT9 (nudix hydrolase 9) | protein interactions | 53343 | 15 | 6 | 17029 | 2761 |
ASNA1,DUT,APP,TRIM11,IMPA2,GLOD4 |
| 2.409e-02 | -3.73 | RAB11FIP3 (RAB11 family interacting protein 3) | protein interactions | 9727 | 15 | 6 | 17029 | 2761 |
ASAP2,RAB11B,RAB11A,ARF5,ARF4,ACAP1 |
| 2.409e-02 | -3.73 | KANSL2 (KAT8 regulatory NSL complex subunit 2) | protein interactions | 54934 | 15 | 6 | 17029 | 2761 |
WDR5,GPBP1L1,TULP3,APP,PPIL2,FERMT3 |
| 2.409e-02 | -3.73 | ARHGAP44 (Rho GTPase activating protein 44) | protein interactions | 9912 | 15 | 6 | 17029 | 2761 |
ARHGAP17,CDC42,SH3BP1,TRIP10,RAC1,WDTC1 |
| 2.409e-02 | -3.73 | Fam60a (family with sequence similarity 60, member A) | protein interactions | 56306 | 15 | 6 | 17029 | 2761 |
SAP130,BRMS1,FOXK1,ARID4A,HDAC2,SAP30 |
| 2.409e-02 | -3.73 | RHO (rhodopsin) | protein interactions | 6010 | 15 | 6 | 17029 | 2761 |
DERL1,PPP2CA,HSPA4,GRK2,ARRB2,DNAJB2 |
| 2.409e-02 | -3.73 | MSLN (mesothelin) | protein interactions | 10232 | 15 | 6 | 17029 | 2761 |
NDUFB9,DDX31,MRPL16,MRM3,LAMTOR3,MPV17 |
| 2.423e-02 | -3.72 | ARIH2 (ariadne RBR E3 ubiquitin protein ligase 2) | protein interactions | 10425 | 69 | 18 | 17029 | 2761 |
WSB2,UBE2D3,SGCE,UBE2E2,UGP2,RPL8,ENSA,UBE2V1,TWF2,EML4,RHEB,MDM2,PDLIM1,TULP3,ARAP1,SOCS6,PML,WDR91 |
| 2.423e-02 | -3.72 | RING1 (ring finger protein 1) | protein interactions | 6015 | 69 | 18 | 17029 | 2761 |
UBE2D3,USP7,UBE2E2,PCGF6,CSNK2A1,WDR5,PCGF1,APP,CBX3,PHC2,RB1,E2F1,USP11,YY1,TERF1,CBX4,RYBP,TERF2 |
| 2.424e-02 | -3.72 | GO_REGULATION_OF_ERBB_SIGNALING_PATHWAY | MSigDB lists | GO_REGULATION_OF_ERBB_SIGNALING_PATHWAY | 79 | 19 | 17377 | 2626 |
ADAM17,RAB7A,EPN1,PSEN1,STAM,APP,RHBDF2,PTPN2,HGS,CDC42,SHC1,RPS27A,ARAP1,SOCS4,AP2B1,NUP62,RBPJ,AP2S1,SOCS5 |
| 2.428e-02 | -3.72 | ganglioglioma | COSMIC cancer mutations | ganglioglioma | 25 | 8 | 17385 | 2587 |
TSC1,TSC2,NF1,PTEN,ETV6,KRAS,H3F3A,CDKN2A |
| 2.428e-02 | -3.72 | dysplasia-carcinoma_in_situ | COSMIC cancer mutations | dysplasia-carcinoma_in_situ | 25 | 8 | 17385 | 2587 |
GNAS,FGFR3,KRAS,NRAS,PTEN,EML4,HRAS,TCF3 |
| 2.430e-02 | -3.72 | GO_INTRINSIC_COMPONENT_OF_MITOCHONDRIAL_INNER_MEMBRANE | MSigDB lists | GO_INTRINSIC_COMPONENT_OF_MITOCHONDRIAL_INNER_MEMBRANE | 16 | 6 | 17377 | 2626 |
CHCHD3,IMMT,APOOL,TIMM23,CHCHD6,TIMM17A |
| 2.430e-02 | -3.72 | GO_NEGATIVE_REGULATION_OF_T_CELL_RECEPTOR_SIGNALING_PATHWAY | MSigDB lists | GO_NEGATIVE_REGULATION_OF_T_CELL_RECEPTOR_SIGNALING_PATHWAY | 16 | 6 | 17377 | 2626 |
PTPN2,EZR,PAWR,DUSP22,DUSP3,PRNP |
| 2.430e-02 | -3.72 | MURAKAMI_UV_RESPONSE_1HR_UP | MSigDB lists | MURAKAMI_UV_RESPONSE_1HR_UP | 16 | 6 | 17377 | 2626 |
PTPRF,PFDN5,SEPT7,MAP3K14,RPSA,DAPK1 |
| 2.430e-02 | -3.72 | GO_MEMBRANE_PROTEIN_INTRACELLULAR_DOMAIN_PROTEOLYSIS | MSigDB lists | GO_MEMBRANE_PROTEIN_INTRACELLULAR_DOMAIN_PROTEOLYSIS | 16 | 6 | 17377 | 2626 |
ADAM17,APH1A,APH1B,SPPL2B,RHBDD1,SPPL2A |
| 2.430e-02 | -3.72 | MODULE_35 | MSigDB lists | MODULE_35 | 16 | 6 | 17377 | 2626 |
KHSRP,KARS,EPRS,IARS,HARS,QARS |
| 2.430e-02 | -3.72 | BIOCARTA_P53_PATHWAY | MSigDB lists | BIOCARTA_P53_PATHWAY | 16 | 6 | 17377 | 2626 |
BCL2,RB1,MDM2,PCNA,CDK2,E2F1 |
| 2.430e-02 | -3.72 | KEGG_OTHER_GLYCAN_DEGRADATION | MSigDB lists | KEGG_OTHER_GLYCAN_DEGRADATION | 16 | 6 | 17377 | 2626 |
MAN2B1,HEXA,MANBA,NEU1,HEXB,GBA |
| 2.430e-02 | -3.72 | BIOCARTA_CDC42RAC_PATHWAY | MSigDB lists | BIOCARTA_CDC42RAC_PATHWAY | 16 | 6 | 17377 | 2626 |
RHOA,CDC42,ARPC1A,ARPC5,ACTR3,RAC1 |
| 2.430e-02 | -3.72 | MACLACHLAN_BRCA1_TARGETS_DN | MSigDB lists | MACLACHLAN_BRCA1_TARGETS_DN | 16 | 6 | 17377 | 2626 |
CD59,BAK1,ACTB,CCNB1,PIN1,RXRB |
| 2.430e-02 | -3.72 | MODULE_110 | MSigDB lists | MODULE_110 | 16 | 6 | 17377 | 2626 |
KHSRP,KARS,EPRS,IARS,HARS,QARS |
| 2.430e-02 | -3.72 | GO_NEGATIVE_REGULATION_OF_VIRAL_RELEASE_FROM_HOST_CELL | MSigDB lists | GO_NEGATIVE_REGULATION_OF_VIRAL_RELEASE_FROM_HOST_CELL | 16 | 6 | 17377 | 2626 |
TRIM32,TRIM8,TRIM26,TRIM28,TRIM11,PML |
| 2.430e-02 | -3.72 | GO_REGULATION_OF_GLUCOSE_IMPORT_IN_RESPONSE_TO_INSULIN_STIMULUS | MSigDB lists | GO_REGULATION_OF_GLUCOSE_IMPORT_IN_RESPONSE_TO_INSULIN_STIMULUS | 16 | 6 | 17377 | 2626 |
RNASEL,OSBPL8,AKT2,PIK3R2,PRKAA1,PTPN11 |
| 2.430e-02 | -3.72 | GO_NEGATIVE_REGULATION_OF_HISTONE_METHYLATION | MSigDB lists | GO_NEGATIVE_REGULATION_OF_HISTONE_METHYLATION | 16 | 6 | 17377 | 2626 |
H2AFY,BRCA1,KDM3A,KDM4A,DNMT1,MECP2 |
| 2.430e-02 | -3.72 | FARMER_BREAST_CANCER_CLUSTER_6 | MSigDB lists | FARMER_BREAST_CANCER_CLUSTER_6 | 16 | 6 | 17377 | 2626 |
RBM47,CERS6,GPD1L,REEP5,RHOB,KIAA0232 |
| 2.430e-02 | -3.72 | NIELSEN_MALIGNAT_FIBROUS_HISTIOCYTOMA_DN | MSigDB lists | NIELSEN_MALIGNAT_FIBROUS_HISTIOCYTOMA_DN | 16 | 6 | 17377 | 2626 |
GNAS,TSHZ1,BCL2,SUB1,BRPF3,WRB |
| 2.430e-02 | -3.72 | GO_COPPER_ION_HOMEOSTASIS | MSigDB lists | GO_COPPER_ION_HOMEOSTASIS | 16 | 6 | 17377 | 2626 |
SLC31A1,ARF1,CUTC,APP,XIAP,PRNP |
| 2.433e-02 | -3.72 | Phagosome | KEGG pathways | ko04145 | 152 | 34 | 7161 | 1149 |
SEC61G,HLA-E,RAC1,TAP1,ATP6V1B2,ITGB5,TFRC,HLA-A,ATP6V0B,CTSS,ATP6V0A2,TAP2,CORO1A,PIKFYVE,ATP6V0D1,ATP6V1G1,SEC61B,RAB7A,ATP6V0A1,RAB5B,CTSL,HLA-B,ATP6V1D,HGS,SEC61A1,STX18,ITGB1,ATP6V0C,ACTB,SCARB1,ATP6V1C1,ATP6V0E1,TUBB,DYNC1LI2 |
| 2.433e-02 | -3.72 | Phagosome | KEGG pathways | hsa04145 | 152 | 34 | 7161 | 1149 |
SEC61G,HLA-E,RAC1,TAP1,ATP6V1B2,ITGB5,TFRC,HLA-A,ATP6V0B,CTSS,ATP6V0A2,TAP2,CORO1A,PIKFYVE,ATP6V0D1,ATP6V1G1,SEC61B,RAB7A,ATP6V0A1,RAB5B,CTSL,HLA-B,ATP6V1D,HGS,SEC61A1,STX18,ITGB1,ATP6V0C,ACTB,SCARB1,ATP6V1C1,ATP6V0E1,TUBB,DYNC1LI2 |
| 2.435e-02 | -3.72 | Zwint (ZW10 interactor) | protein interactions | 52696 | 19 | 7 | 17029 | 2761 |
NUP62,NUF2,DSN1,GOLGA2,PRKCSH,TACC3,OGT |
| 2.435e-02 | -3.72 | SBNO1 (strawberry notch homolog 1) | protein interactions | 55206 | 19 | 7 | 17029 | 2761 |
SUB1,RBM25,MCM2,IVNS1ABP,WDYHV1,SEC24C,SSRP1 |
| 2.435e-02 | -3.72 | RHOB (ras homolog family member B) | protein interactions | 388 | 19 | 7 | 17029 | 2761 |
PPP2CA,FNTA,RBX1,PGGT1B,CORO1C,RAC1,LAMTOR3 |
| 2.435e-02 | -3.72 | C18orf21 (chromosome 18 open reading frame 21) | protein interactions | 83608 | 19 | 7 | 17029 | 2761 |
RPP25,KIF22,KIF18A,HUWE1,APP,MECP2,POP7 |
| 2.435e-02 | -3.72 | Cdca5 (cell division cycle associated 5) | protein interactions | 67849 | 19 | 7 | 17029 | 2761 |
AURKB,SMC3,ATP5MF,REPS2,MRPL55,PDS5B,SF3B2 |
| 2.435e-02 | -3.72 | TBC1D23 (TBC1 domain family member 23) | protein interactions | 55773 | 19 | 7 | 17029 | 2761 |
STK11,WDR62,API5,GLRX3,FLYWCH2,SSBP3,KBTBD7 |
| 2.435e-02 | -3.72 | DMRTB1 (DMRT like family B with proline rich C-terminal 1) | protein interactions | 63948 | 19 | 7 | 17029 | 2761 |
VASP,EWSR1,PRMT2,PEF1,KLHL15,EYA2,TRIM11 |
| 2.435e-02 | -3.72 | MAF1 (MAF1 homolog, negative regulator of RNA polymerase III) | protein interactions | 84232 | 19 | 7 | 17029 | 2761 |
VCPIP1,CSNK2A1,SUMO2,CSNK1D,CDKN2A,NUDT3,RAD54B |
| 2.435e-02 | -3.72 | TIMM17B (translocase of inner mitochondrial membrane 17B) | protein interactions | 10245 | 19 | 7 | 17029 | 2761 |
TOMM20,SRSF5,DUSP22,TIMM23,APP,MRPL32,TIMM50 |
| 2.435e-02 | -3.72 | RCL1 (RNA terminal phosphate cyclase like 1) | protein interactions | 10171 | 19 | 7 | 17029 | 2761 |
PTPN2,USF1,BRCA1,TFG,SUZ12,IFI16,GEMIN7 |
| 2.435e-02 | -3.72 | ARHGDIB (Rho GDP dissociation inhibitor beta) | protein interactions | 397 | 19 | 7 | 17029 | 2761 |
EZR,VAV1,RHOA,CDC42,RHOC,APP,RAC1 |
| 2.435e-02 | -3.72 | DBI (diazepam binding inhibitor, acyl-CoA binding protein) | protein interactions | 1622 | 19 | 7 | 17029 | 2761 |
UBXN2A,MAP1LC3B,RAD23B,PPCDC,NIPSNAP1,RAD23A,NSFL1C |
| 2.435e-02 | -3.72 | Anapc5 (anaphase-promoting complex subunit 5) | protein interactions | 59008 | 19 | 7 | 17029 | 2761 |
ANAPC2,ANAPC7,CDC16,CDC23,CDC27,SMURF1,ANAPC4 |
| 2.435e-02 | -3.72 | TMEFF1 (transmembrane protein with EGF like and two follistatin like domains 1) | protein interactions | 8577 | 19 | 7 | 17029 | 2761 |
CLDND1,THNSL1,METTL9,GOLGA7,INTS7,ATP2C1,HADHB |
| 2.435e-02 | -3.72 | COMMD9 (COMM domain containing 9) | protein interactions | 29099 | 19 | 7 | 17029 | 2761 |
CCDC93,COMMD10,XPO7,COMMD6,COMMD4,COMMD8,VPS29 |
| 2.435e-02 | -3.72 | SPATS2 (spermatogenesis associated serine rich 2) | protein interactions | 65244 | 19 | 7 | 17029 | 2761 |
FGFR1OP,PCM1,NRAS,KIF11,APP,SSSCA1,IFI16 |
| 2.435e-02 | -3.72 | FBXO17 (F-box protein 17) | protein interactions | 115290 | 19 | 7 | 17029 | 2761 |
FBXW2,CUL1,COPS7B,COPS6,NDUFA2,RBX1,NMT2 |
| 2.435e-02 | -3.72 | RPS6KA4 (ribosomal protein S6 kinase A4) | protein interactions | 8986 | 19 | 7 | 17029 | 2761 |
HMGN1,CREB1,MAPK1,MAPK14,MAPK3,DDX42,CDC37 |
| 2.435e-02 | -3.72 | TEX13A (testis expressed 13A) | protein interactions | 56157 | 19 | 7 | 17029 | 2761 |
CNOT9,CNOT6,CNOT6L,CNOT11,ASPM,SETD3,CNOT3 |
| 2.435e-02 | -3.72 | UBE3D (ubiquitin protein ligase E3D) | protein interactions | 90025 | 19 | 7 | 17029 | 2761 |
CCNB1,BORA,UBE2C,TSC22D3,DNAAF2,CCM2,MEMO1 |
| 2.435e-02 | -3.72 | RAP2C (RAP2C, member of RAS oncogene family) | protein interactions | 57826 | 19 | 7 | 17029 | 2761 |
CCT2,ADRB2,RHOA,RAB1A,DDX39A,MAP4K4,RPS10 |
| 2.442e-02 | -3.71 | GO_REGULATION_OF_CYSTEINE_TYPE_ENDOPEPTIDASE_ACTIVITY | MSigDB lists | GO_REGULATION_OF_CYSTEINE_TYPE_ENDOPEPTIDASE_ACTIVITY | 206 | 42 | 17377 | 2626 |
BCL2L12,RPS6KA1,DAP,RAF1,XIAP,CSNK2A1,PAWR,CYCS,BIRC2,BCAP31,PARK7,APOPT1,TFAP4,MDM2,TNFAIP8,DAPK1,ARL6IP1,CDKN1B,PDCD2,F2R,SENP1,HTRA2,BAK1,BIRC3,AKT2,RFFL,CYFIP2,PSMB9,FADD,FAS,PDCD6,BIRC5,PRDX3,PRDX5,PML,SIAH2,GPI,MAP3K5,ARRB2,IGBP1,IFI16,CDKN2A |
| 2.450e-02 | -3.71 | UBQ-conjugat_E2 | interpro domains | IPR000608 | 39 | 11 | 18492 | 2768 |
UBE2D3,UBE2E2,UBE2Q2,UBE2Q1,UBE2Z,UBE2V1,KRAS,UBE2I,UBE2C,UBE2M,UBE2QL1 |
| 2.454e-02 | -3.71 | GSE339_CD4POS_VS_CD4CD8DN_DC_DN | MSigDB lists | GSE339_CD4POS_VS_CD4CD8DN_DC_DN | 189 | 39 | 17377 | 2626 |
TMED7,GOLIM4,POLR2K,MRPL39,ZFP91,PPP1R15B,CDK2AP2,UCK2,FKBP1A,RPN1,SLC31A1,NEK6,GRSF1,GTSE1,ALDH9A1,IFRD1,HMGN5,RNASEH2C,NUDT4,JTB,PSMB7,ARID1A,MCM2,SOX4,ODC1,LUC7L,MATR3,DHX15,MAT2A,PRDX1,DPYSL3,KPNA1,AHNAK,CCDC86,TMED10,OGT,COIL,PDCD2L,MRPL3 |
| 2.454e-02 | -3.71 | GSE31082_DP_VS_CD8_SP_THYMOCYTE_DN | MSigDB lists | GSE31082_DP_VS_CD8_SP_THYMOCYTE_DN | 189 | 39 | 17377 | 2626 |
MIF,SLC12A7,HIVEP3,HECA,SCAMP3,AGRN,SRGN,MYH9,GLUD1,NOTCH2,TMEM165,PABPC4,IRF4,FBXL6,AQR,ALDH18A1,F2R,LPCAT1,RPL22L1,PPA1,KCNAB2,TRIM14,EEF1D,PTPN18,RPL35,AATF,MFNG,SLC26A6,ABHD11,PRMT2,ODC1,RPL37,SH3BP5,NSF,PDRG1,TFE3,LY75,GALNT10,RNF114 |
| 2.454e-02 | -3.71 | GSE34006_UNTREATED_VS_A2AR_AGONIST_TREATED_TREG_DN | MSigDB lists | GSE34006_UNTREATED_VS_A2AR_AGONIST_TREATED_TREG_DN | 189 | 39 | 17377 | 2626 |
UBE2D3,PIGM,PHF23,RPS6KA1,GADD45G,SLC2A1,LAGE3,CTCF,PTP4A3,GLUD1,SLC29A1,MAN2B1,PPP3CB,SLC20A1,IL21R,REEP5,GNB2,CDKN2C,PA2G4,VASP,KLHL20,PELO,PRC1,FAM89B,ORAI1,CORO1A,MOB1A,LPCAT1,TNRC18,PCBP2,DENND1B,PPP1R21,ADRB2,COMMD4,NRM,PPM1G,ACTB,CTSA,AKNA |
| 2.454e-02 | -3.71 | GSE36891_UNSTIM_VS_POLYIC_TLR3_STIM_PERITONEAL_MACROPHAGE_DN | MSigDB lists | GSE36891_UNSTIM_VS_POLYIC_TLR3_STIM_PERITONEAL_MACROPHAGE_DN | 189 | 39 | 17377 | 2626 |
FEZ2,PARP12,PTTG1,C5orf30,PCSK7,SNN,LYN,HEATR5B,TMCC3,PRNP,APOOL,MINPP1,MCMBP,ZNF800,MORC3,CYTH1,ZDHHC18,ARHGAP17,ETV3,DENND1B,USP42,FBXO9,TOR1AIP2,UTP3,AZI2,OGFR,HHEX,CCDC86,L3MBTL3,RBL1,ARNTL,PML,VCPIP1,CHMP4B,TCOF1,NAA20,PLOD3,TSTD2,FAM72A |
| 2.454e-02 | -3.71 | GSE19401_PAM2CSK4_VS_RETINOIC_ACID_AND_PAM2CSK4_STIM_FOLLICULAR_DC_DN | MSigDB lists | GSE19401_PAM2CSK4_VS_RETINOIC_ACID_AND_PAM2CSK4_STIM_FOLLICULAR_DC_DN | 189 | 39 | 17377 | 2626 |
GALK1,THOC1,ANXA6,KLHL18,ASAH1,MEF2A,GGA2,ITGB5,MYL6B,MRPL19,PIP4K2A,CAPN2,DECR1,MTMR4,EI24,MARCH2,PLCL2,PDIA6,GM2A,NIPSNAP1,TIMP2,SEPT9,GALC,NQO2,GBA,EXOSC9,PDE3B,MAN2A2,NUCB1,PON2,TFDP1,NAGLU,ACAT1,CABIN1,ACADM,CLN3,PLOD3,XRCC4,HEXA |
| 2.454e-02 | -3.71 | GSE30153_LUPUS_VS_HEALTHY_DONOR_BCELL_UP | MSigDB lists | GSE30153_LUPUS_VS_HEALTHY_DONOR_BCELL_UP | 189 | 39 | 17377 | 2626 |
MBD1,CCNC,CYLD,FEZ2,PDAP1,TCF3,MED13L,KLHL18,CHKB,GYG1,EIF1B,PNO1,HOMER1,CS,SPTSSA,PHKG2,MYO5A,CFL1,RBM15B,MLEC,RPS10,MTMR6,CDC6,RAB22A,ISG15,HSPA4,SEC23IP,BRWD1,CERS6,ELMO1,TBL3,UBXN2B,MAPK6,UHRF2,SLC16A1,MEGF9,ST3GAL2,POT1,USP13 |
| 2.454e-02 | -3.71 | GSE360_T_GONDII_VS_B_MALAYI_HIGH_DOSE_MAC_DN | MSigDB lists | GSE360_T_GONDII_VS_B_MALAYI_HIGH_DOSE_MAC_DN | 189 | 39 | 17377 | 2626 |
CHMP2A,TMEM184B,DAP,RAE1,TAP1,SND1,FKBP2,PSMD9,NDUFS7,CNOT3,ATG4A,MLX,SLC1A4,MED8,SH3BP1,INTS1,BANF1,PCYT2,CYB5R1,CLTB,F2R,KCNAB2,CYFIP1,RHOA,TSPAN31,GALK2,ERC1,NEU1,MYO1F,TPD52L2,ALDH3B1,CLK3,COX7A2L,OAZ2,WDR7,RGL1,ZNF45,HEXA,LTA4H |
| 2.454e-02 | -3.71 | GSE20366_EX_VIVO_VS_HOMEOSTATIC_CONVERSION_NAIVE_CD4_TCELL_UP | MSigDB lists | GSE20366_EX_VIVO_VS_HOMEOSTATIC_CONVERSION_NAIVE_CD4_TCELL_UP | 189 | 39 | 17377 | 2626 |
RECQL,CHD1L,KCTD17,KLC1,NKRF,PPP3CB,XPNPEP3,DOCK11,BRIX1,CSNK1A1,ANKIB1,RBM4,RSAD1,HNRNPA2B1,HOMER1,RINL,PIK3IP1,PPP6R1,ABCC5,FDFT1,SRSF11,GCC2,PGGT1B,DCAF8,ZMYM5,TEX10,USP10,NUP155,IL12RB1,AP4E1,TSR2,MAT2A,RPA1,VEZF1,ZNF180,ZNF330,ATF6,GLCCI1,CABLES1 |
| 2.454e-02 | -3.71 | GSE17721_PAM3CSK4_VS_CPG_1H_BMDC_UP | MSigDB lists | GSE17721_PAM3CSK4_VS_CPG_1H_BMDC_UP | 189 | 39 | 17377 | 2626 |
CTDP1,RECQL,MRPL9,DNMT3A,MRPS15,DYNLL1,VPS45,UBE4A,ARF1,SNN,HAUS2,APP,NUDT19,SIVA1,AP1M1,PDCD2,ACSL5,AGGF1,AATF,PPP1R21,PIP4K2C,ATXN1,CDC6,NFATC2IP,WDR81,MTX1,MCM2,KRTCAP2,MYO1F,MFN2,SDHB,FNTA,BRWD1,TMED10,U2SURP,ACLY,PLOD3,LONP2,CHID1 |
| 2.454e-02 | -3.71 | GSE17721_CPG_VS_GARDIQUIMOD_8H_BMDC_UP | MSigDB lists | GSE17721_CPG_VS_GARDIQUIMOD_8H_BMDC_UP | 189 | 39 | 17377 | 2626 |
GOLPH3L,UQCR10,C19orf25,NIPA2,ARGLU1,CHAC2,RGS2,CSNK1A1,GLRX3,FBXO22,RGS1,PA2G4,NDUFV1,SSBP3,PPIL2,POP7,BUD31,AKR1B1,NDUFS8,SGCB,FTSJ3,ARHGAP17,LAP3,CPOX,ITM2A,OGFR,ASB13,TPD52L2,RBMX,GADD45B,DNAJC17,RWDD4,TMEM219,KPNA2,COPS6,BRWD3,CD81,IGBP1,CHID1 |
| 2.454e-02 | -3.71 | GSE17721_CTRL_VS_CPG_24H_BMDC_UP | MSigDB lists | GSE17721_CTRL_VS_CPG_24H_BMDC_UP | 189 | 39 | 17377 | 2626 |
CTDP1,ASH1L,DDX47,FEZ2,MAX,ADD1,DEPDC1,KIAA0100,GSPT2,CENPF,HABP4,HEXB,CDCA3,LETMD1,FOXO3,HAUS2,ABHD16A,CNPY3,IFT46,CTDSP2,CAMK2G,KDELR1,CYTH1,GABPA,DENND4C,MAN1B1,GALK2,CHCHD6,ANKRD46,EPB41,ANKZF1,DERL1,JAK1,LUC7L3,DDX5,MBD6,DNAJC30,HEXA,EYA2 |
| 2.454e-02 | -3.71 | GSE16385_ROSIGLITAZONE_IL4_VS_IFNG_TNF_STIM_MACROPHAGE_UP | MSigDB lists | GSE16385_ROSIGLITAZONE_IL4_VS_IFNG_TNF_STIM_MACROPHAGE_UP | 189 | 39 | 17377 | 2626 |
DDX58,PARP12,ABCC10,SUPT7L,BIRC2,ADD3,SHC1,KDM2A,IL6ST,LTN1,PIK3IP1,MVP,MAML1,VPS13B,PLK3,MOB4,GCC2,KLF10,COQ10B,TYW1,PIP4K2C,PFKFB3,KRAS,PRPF3,HAGH,GOSR1,STX16,STK17B,USP36,RBM38,MAN2A2,SGSH,JAK1,OSBPL8,CAB39,GALNT10,CHMP7,TOB1,N4BP2L2 |
| 2.454e-02 | -3.71 | GSE17721_0.5H_VS_12H_POLYIC_BMDC_DN | MSigDB lists | GSE17721_0.5H_VS_12H_POLYIC_BMDC_DN | 189 | 39 | 17377 | 2626 |
WASF2,PKP4,TRIP12,GPBP1L1,PPP1R15B,DLGAP4,NKD2,PLAGL2,DHX8,PXMP2,DNAJB1,CMTM6,KTN1,TMEM179B,HOMER1,DDA1,FRMD8,UBE2M,TXNL1,STAU1,FTL,ATP13A1,BIRC3,SNX2,ILF3,MCL1,PEF1,GOSR1,PLEKHF2,NEU1,ARF4,PI4K2A,PPP2R5A,CLK3,LUC7L3,ZNF436,BAZ1B,TRAF5,STARD3NL |
| 2.454e-02 | -3.71 | GSE35685_CD34POS_CD38NEG_VS_CD34POS_CD10POS_BONE_MARROW_UP | MSigDB lists | GSE35685_CD34POS_CD38NEG_VS_CD34POS_CD10POS_BONE_MARROW_UP | 189 | 39 | 17377 | 2626 |
RMND5A,CCDC93,RHOG,CMAS,GNPDA1,KLHL21,MAGED1,MOGS,ABCB10,SLC25A44,IKBIP,TWF2,MAPK14,FOXO3,GFM2,LIN9,CYHR1,MDM2,SLC38A5,AP2B1,KIF22,COPS7B,LPCAT1,ABCC1,NIPSNAP1,ERCC1,POLR2I,ERF,NSDHL,BTG2,DIDO1,FAM50B,KDM3A,PEF1,RBM38,RHOB,RXRB,ARNTL,SLC25A39 |
| 2.454e-02 | -3.71 | GO_REGULATION_OF_DEFENSE_RESPONSE_TO_VIRUS | MSigDB lists | GO_REGULATION_OF_DEFENSE_RESPONSE_TO_VIRUS | 189 | 39 | 17377 | 2626 |
DDX58,TMEM203,MRPS2,RAC1,ALKBH5,EIF2AK4,ARF1,AP1B1,ELMOD2,BIRC2,HLA-A,RFWD3,FANCL,DNAAF2,AP1M1,AP2B1,ANXA5,MAVS,C8orf59,PCBP2,ZNF189,BIRC3,TNFAIP3,TMEM39A,SNRPB,CRNKL1,MRPS10,PACS1,KCNQ1,IL12RB1,ELMO1,COX8A,PML,SLC25A19,AP1S1,MDH1,SMURF1,AP2S1,ZC3HAV1 |
| 2.455e-02 | -3.71 | Calnexin/calreticulin cycle | REACTOME pathways | R-HSA-901042 | 27 | 9 | 10287 | 1696 |
PRKCSH,RPS27A,MAN1B1,SEL1L,SYVN1,EDEM2,RNF139,RNF5,RNF103 |
| 2.455e-02 | -3.71 | RNA Pol II CTD phosphorylation and interaction with CE during HIV infection | REACTOME pathways | R-HSA-167160 | 27 | 9 | 10287 | 1696 |
POLR2I,POLR2J,POLR2G,POLR2L,POLR2K,POLR2D,GTF2H2,POLR2A,GTF2F1 |
| 2.455e-02 | -3.71 | RNA Pol II CTD phosphorylation and interaction with CE | REACTOME pathways | R-HSA-77075 | 27 | 9 | 10287 | 1696 |
POLR2I,POLR2G,POLR2L,POLR2J,POLR2K,POLR2D,GTF2H2,POLR2A,GTF2F1 |
| 2.456e-02 | -3.71 | synovial_sarcoma | COSMIC cancer mutations | synovial_sarcoma | 91 | 21 | 17385 | 2587 |
SGCE,EWSR1,NRAS,TRIP12,NF1,SF3B1,KRAS,GORASP2,OGDH,KCNQ1,DHX57,RB1,DNAJC10,PTEN,ETV6,STK11,SS18L1,FUS,TRAF5,HRAS,CDKN2A |
| 2.458e-02 | -3.71 | endocytosis | biological process | GO:0006897 | 540 | 99 | 17256 | 2622 |
WASF2,RHOG,RAB14,TSC2,TRIP10,RAC1,ACTR3,MYH9,CDC42SE2,BCL2L1,LYN,BECN1,RUFY1,SYNRG,REPS1,APP,CDK5,VAV1,CDC42,SH3BP1,DPYSL2,RABGAP1L,PIK3R2,DNM2,AP2B1,CORO1A,MARCH2,CLTB,PDIA6,CARMIL1,ABI1,SNX8,RHOBTB3,NCK1,PPT1,RAB7A,WIPF1,EZR,LRP5,RAB1A,RAB22A,NECAP2,WAS,CORO1C,LIMK1,ITGB1,AP1S1,ACTB,SCARB1,CLN3,ARRB2,MAPK1,AP2S1,ABCA1,LRP8,CSNK1D,ANXA11,HSPH1,TM9SF4,VAV2,TMX3,EPN1,JMJD6,NCKAP1,CSNK1A1,SCYL2,HEATR5B,TFRC,PIP5K1C,GRK2,ARPC5,SNX18,RINL,PIKFYVE,LDLRAD3,LRSAM1,GTF2H2,CSNK1G3,APOL1,CYFIP1,CSNK1G2,SNX2,MAPKAPK3,DENND1B,EIF2AK1,ADRB2,CYFIP2,ARPC1A,PICALM,MAPK3,SCARB2,ELMO1,CSNK1G1,LY75,USP20,EHD4,CD81,HRAS,ESYT2 |
| 2.460e-02 | -3.70 | GO_MICROTUBULE_DEPOLYMERIZATION | MSigDB lists | GO_MICROTUBULE_DEPOLYMERIZATION | 12 | 5 | 17377 | 2626 |
KIF2C,KIF18A,KIF18B,STMN1,KIF14 |
| 2.460e-02 | -3.70 | CLAUS_PGR_POSITIVE_MENINGIOMA_DN | MSigDB lists | CLAUS_PGR_POSITIVE_MENINGIOMA_DN | 12 | 5 | 17377 | 2626 |
NLN,MEGF9,BCL2,SOX4,MAP4K4 |
| 2.460e-02 | -3.70 | GO_RNA_POLYMERASE_I_ACTIVITY | MSigDB lists | GO_RNA_POLYMERASE_I_ACTIVITY | 12 | 5 | 17377 | 2626 |
POLR1B,POLR2L,POLR2K,ZNRD1,TWISTNB |
| 2.460e-02 | -3.70 | GO_TAU_PROTEIN_KINASE_ACTIVITY | MSigDB lists | GO_TAU_PROTEIN_KINASE_ACTIVITY | 12 | 5 | 17377 | 2626 |
CDK5,PHKG2,MARK2,PRKAA1,CSNK1D |
| 2.460e-02 | -3.70 | GO_METHYLOSOME | MSigDB lists | GO_METHYLOSOME | 12 | 5 | 17377 | 2626 |
ERH,SNRPG,SNRPD3,SNRPB,CLNS1A |
| 2.460e-02 | -3.70 | REACTOME_CASPASE_MEDIATED_CLEAVAGE_OF_CYTOSKELETAL_PROTEINS | MSigDB lists | REACTOME_CASPASE_MEDIATED_CLEAVAGE_OF_CYTOSKELETAL_PROTEINS | 12 | 5 | 17377 | 2626 |
GAS2,PLEC,ADD1,CASP6,SPTAN1 |
| 2.460e-02 | -3.70 | GO_DEOXYRIBONUCLEOTIDE_BIOSYNTHETIC_PROCESS | MSigDB lists | GO_DEOXYRIBONUCLEOTIDE_BIOSYNTHETIC_PROCESS | 12 | 5 | 17377 | 2626 |
RRM2,GUK1,DUT,TBPL1,RRM1 |
| 2.460e-02 | -3.70 | GO_REGULATION_OF_RAC_PROTEIN_SIGNAL_TRANSDUCTION | MSigDB lists | GO_REGULATION_OF_RAC_PROTEIN_SIGNAL_TRANSDUCTION | 12 | 5 | 17377 | 2626 |
KRAS,NF1,ALS2,OGT,DNM2 |
| 2.460e-02 | -3.70 | GO_HOST | MSigDB lists | GO_HOST | 12 | 5 | 17377 | 2626 |
DERL1,TAP2,LMAN1,TAP1,PI4K2A |
| 2.460e-02 | -3.70 | GO_POLY_A_BINDING | MSigDB lists | GO_POLY_A_BINDING | 12 | 5 | 17377 | 2626 |
TIA1,SYNCRIP,EIF4A3,PABPC1,PABPC4 |
| 2.460e-02 | -3.70 | GO_GLYCOLIPID_CATABOLIC_PROCESS | MSigDB lists | GO_GLYCOLIPID_CATABOLIC_PROCESS | 12 | 5 | 17377 | 2626 |
GALC,GM2A,NEU1,HEXB,GBA |
| 2.460e-02 | -3.70 | BIOCARTA_BARR_MAPK_PATHWAY | MSigDB lists | BIOCARTA_BARR_MAPK_PATHWAY | 12 | 5 | 17377 | 2626 |
GNAS,MAPK1,MAP2K2,RAF1,MAPK3 |
| 2.460e-02 | -3.70 | GO_NPBAF_COMPLEX | MSigDB lists | GO_NPBAF_COMPLEX | 12 | 5 | 17377 | 2626 |
SMARCA4,PHF10,ARID1A,SMARCE1,SMARCD1 |
| 2.460e-02 | -3.70 | GO_ALDEHYDE_CATABOLIC_PROCESS | MSigDB lists | GO_ALDEHYDE_CATABOLIC_PROCESS | 12 | 5 | 17377 | 2626 |
ALDH3B1,PDXP,GPI,HAGH,PARK7 |
| 2.460e-02 | -3.70 | GO_PROTEASOME_REGULATORY_PARTICLE_BASE_SUBCOMPLEX | MSigDB lists | GO_PROTEASOME_REGULATORY_PARTICLE_BASE_SUBCOMPLEX | 12 | 5 | 17377 | 2626 |
PSMD2,PSMD1,PSMD9,PSMC1,PSMC4 |
| 2.460e-02 | -3.70 | REACTOME_AKT_PHOSPHORYLATES_TARGETS_IN_THE_CYTOSOL | MSigDB lists | REACTOME_AKT_PHOSPHORYLATES_TARGETS_IN_THE_CYTOSOL | 12 | 5 | 17377 | 2626 |
CDKN1B,MDM2,AKT1S1,TSC2,AKT2 |
| 2.460e-02 | -3.70 | REACTOME_SIGNALING_BY_NOTCH2 | MSigDB lists | REACTOME_SIGNALING_BY_NOTCH2 | 12 | 5 | 17377 | 2626 |
NOTCH2,PSEN1,ADAM10,APH1A,APH1B |
| 2.460e-02 | -3.70 | GO_CYTOPLASMIC_UBIQUITIN_LIGASE_COMPLEX | MSigDB lists | GO_CYTOPLASMIC_UBIQUITIN_LIGASE_COMPLEX | 12 | 5 | 17377 | 2626 |
SYVN1,RBX1,ATG3,VHL,SEL1L |
| 2.461e-02 | -3.70 | regulation of protein localization to nucleus | biological process | GO:1900180 | 116 | 26 | 17256 | 2622 |
PLK1,TGFB1,CCT2,TXN,KAT7,RAB23,NUP54,NUTF2,MAPK14,PSEN1,CCT8,PARK7,TRIM28,LMNA,GLIS2,PIN1,PIK3R2,GTSE1,NUP62,STK11,MDFIC,MAVS,MAPK1,NMD3,NUP58,CHP1 |
| 2.461e-02 | -3.70 | HAUS8 (HAUS augmin like complex subunit 8) | protein interactions | 93323 | 50 | 14 | 17029 | 2761 |
FGFR1OP,CEP104,CDC16,PCM1,CCDC14,CENPJ,ODF2,MTMR12,CEP63,SASS6,APP,HAUS2,POC5,DCTN1 |
| 2.461e-02 | -3.70 | NELFB (negative elongation factor complex member B) | protein interactions | 25920 | 50 | 14 | 17029 | 2761 |
RPN1,PA2G4,ATP1A1,SYNCRIP,MAPK6,DHX9,MSH2,YBX1,BRCA1,ABCF1,CCT8,FKBP3,POLR2A,RPL23A |
| 2.461e-02 | -3.70 | TTC4 (tetratricopeptide repeat domain 4) | protein interactions | 7268 | 50 | 14 | 17029 | 2761 |
GCC2,NPHP4,HGS,UPF1,AHSA1,TRMT6,CTPS1,FKBP5,UBE4B,EDRF1,APPL1,VPS29,SAC3D1,CDC37 |
| 2.461e-02 | -3.70 | LIMK1 (LIM domain kinase 1) | protein interactions | 3984 | 50 | 14 | 17029 | 2761 |
HSPA4,SARNP,LIMK1,POLR2D,KIF23,YWHAZ,ERBIN,ROCK1,ARRB2,MAPK14,ABCA1,APP,CFL1,RLIM |
| 2.461e-02 | -3.70 | RHEB (Ras homolog, mTORC1 binding) | protein interactions | 6009 | 50 | 14 | 17029 | 2761 |
TSC1,RAP1A,ITGB8,TSC2,RAF1,RAB7A,RAC1,BCL2,NFATC2IP,VPS4A,PSEN1,HRAS,MLST8,LDHB |
| 2.461e-02 | -3.70 | PPARA (peroxisome proliferator activated receptor alpha) | protein interactions | 5465 | 50 | 14 | 17029 | 2761 |
NCOR2,DAP3,DUT,GADD45B,GADD45G,STAT1,MECR,BCL2,NCOA1,UBE2I,MAPK1,NCOA2,MAPK3,RXRB |
| 2.462e-02 | -3.70 | Central carbon metabolism in cancer | KEGG pathways | hsa05230 | 65 | 17 | 7161 | 1149 |
FGFR3,NRAS,TIGAR,PTEN,AKT2,RAF1,PIK3R2,SLC2A1,LDHA,KRAS,PKM,PGAM1,MAPK1,MAP2K2,HRAS,PFKP,MAPK3 |
| 2.462e-02 | -3.70 | Central carbon metabolism in cancer | KEGG pathways | ko05230 | 65 | 17 | 7161 | 1149 |
FGFR3,NRAS,TIGAR,PTEN,AKT2,RAF1,PIK3R2,SLC2A1,LDHA,KRAS,PKM,PGAM1,MAPK1,MAP2K2,HRAS,PFKP,MAPK3 |
| 2.464e-02 | -3.70 | GABARAP (GABA type A receptor-associated protein) | protein interactions | 11337 | 74 | 19 | 17029 | 2761 |
PKP4,RB1CC1,PGS1,CUL3,MAP1LC3B,TFRC,MPC1,OPTN,PI4K2A,KEAP1,NSF,ATG3,KBTBD7,ATG13,FNIP2,NIPSNAP2,DVL2,NIPSNAP1,SRPK2 |
| 2.464e-02 | -3.70 | USP14 (ubiquitin specific peptidase 14) | protein interactions | 9097 | 74 | 19 | 17029 | 2761 |
TXNL1,USP7,UNK,BCL2L1,CCNB1,XPO7,USP21,SH3GLB1,PSMC4,RAD23A,DERL1,PSMD2,PSMA6,AHNAK,PSMD1,UCHL5,PSMD3,CHMP7,PSMC1 |
| 2.464e-02 | -3.70 | VAV2 (vav guanine nucleotide exchange factor 2) | protein interactions | 7410 | 74 | 19 | 17029 | 2761 |
RHOG,CCT2,PHF10,HSPH1,RHOA,ST13,VAV2,RAC1,HNRNPF,UBE4B,DCUN1D4,SRRT,RAD23A,TPD52L2,FNTA,CRCP,VCPIP1,IPO4,SRPK2 |
| 2.473e-02 | -3.70 | CSA_PPIASE_2 | prosite domains | PS50072 | 22 | 7 | 12060 | 1670 |
PPIF,PPIB,PPWD1,CWC27,PPIG,PPIE,PPIL2 |
| 2.473e-02 | -3.70 | FHA_DOMAIN | prosite domains | PS50006 | 22 | 7 | 12060 | 1670 |
CEP170B,CHEK2,AGGF1,FOXK1,TCF19,PPP1R8,MKI67 |
| 2.474e-02 | -3.70 | macromolecule transmembrane transporter activity | molecular function | GO:0022884 | 20 | 7 | 17224 | 2647 |
MCL1,SEC61B,TOMM20,TOMM40,SEC61G,TIMM23,TIMM17A |
| 2.481e-02 | -3.70 | Insulin Signalling | SMPDB pathways | SMP00391 | 11 | 5 | 992 | 167 |
PDPK1,MAPK1,HRAS,MAP2K2,RAF1 |
| 2.485e-02 | -3.69 | G_SEPTIN | prosite domains | PS51719 | 13 | 5 | 12060 | 1670 |
SEPT8,SEPT11,SEPT1,SEPT7,SEPT9 |
| 2.485e-02 | -3.69 | UBX | prosite domains | PS50033 | 13 | 5 | 12060 | 1670 |
UBXN2A,UBXN2B,UBXN1,FAF1,NSFL1C |
| 2.485e-02 | -3.69 | SER_THR_PHOSPHATASE | prosite domains | PS00125 | 13 | 5 | 12060 | 1670 |
PPP2CA,PPP3CA,PPP3CB,PPP5C,PPP6C |
| 2.486e-02 | -3.69 | BCOR (BCL6 corepressor) | protein interactions | 54880 | 104 | 25 | 17029 | 2761 |
CPNE1,USP7,NCOR2,DCAF15,TCF3,EIF3D,USP42,TKT,TIA1,LETMD1,PCGF1,HMG20A,CDC16,HSPA4,NSF,NAA50,CS,PQBP1,NAP1L4,SGF29,EYA2,KCNAB2,DDB1,SMC4,RYBP |
| 2.491e-02 | -3.69 | ATL3 (atlastin GTPase 3) | protein interactions | 25923 | 79 | 20 | 17029 | 2761 |
RAB14,PHB2,ZNF768,SRSF6,TMEM109,TAP1,SLC4A2,ESYT1,RAB1A,APP,GART,ITGB1,PGRMC1,TAP2,ATP5F1A,MRPL40,ATP6V1C1,RTN3,SNX14,RNF5 |
| 2.491e-02 | -3.69 | pyrimidine nucleoside monophosphate biosynthetic process | biological process | GO:0009130 | 16 | 6 | 17256 | 2622 |
UPRT,UCK1,DCTD,DUT,HDDC2,UCK2 |
| 2.491e-02 | -3.69 | DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator | biological process | GO:0006978 | 16 | 6 | 17256 | 2622 |
TFAP4,CHEK2,BRCA1,SP100,FOXM1,HIPK2 |
| 2.491e-02 | -3.69 | microtubule depolymerization | biological process | GO:0007019 | 16 | 6 | 17256 | 2622 |
KIF2A,KIF18A,KIF2C,KIF18B,STMN1,KIF14 |
| 2.491e-02 | -3.69 | positive regulation of histone H3-K4 methylation | biological process | GO:0051571 | 16 | 6 | 17256 | 2622 |
CTR9,RTF1,BRCA1,KMT2E,DNMT1,SMAD4 |
| 2.491e-02 | -3.69 | negative regulation of ubiquitin-protein transferase activity | biological process | GO:0051444 | 16 | 6 | 17256 | 2622 |
PSEN1,LIMK1,PARK7,MAD2L2,RPL11,FBXO5 |
| 2.491e-02 | -3.69 | regulation of Golgi organization | biological process | GO:1903358 | 16 | 6 | 17256 | 2622 |
MAPK1,MAP2K2,STX18,MYO5A,MAPK3,DNM2 |
| 2.492e-02 | -3.69 | GSE27859_MACROPHAGE_VS_CD11C_INT_F480_INT_DC_UP | MSigDB lists | GSE27859_MACROPHAGE_VS_CD11C_INT_F480_INT_DC_UP | 161 | 34 | 17377 | 2626 |
OTUD5,ANKRD27,PPP1R12A,AGTRAP,DAP,MDH2,TCF3,BRAP,SDF2L1,CMTM6,SEC11A,CLIC4,ETV6,PARL,DCP1A,MVP,MOB1A,SENP1,HEMK1,LRRC8A,NFATC2,TANC1,VDAC1,EML4,IRF5,LEMD2,GALNT2,CDKN2AIPNL,TMEM168,TWSG1,ITGB1,RBPJ,HIPK3,NAA60 |
| 2.493e-02 | -3.69 | human chr7q22.3 | chromosome location | human chr7q22.3 | 22 | 6 | 26185 | 2809 |
CBLL1,BCAP29,DUS4L,CCDC71L,KMT2E,SRPK2 |
| 2.493e-02 | -3.69 | human chr10q25.2 | chromosome location | human chr10q25.2 | 22 | 6 | 26185 | 2809 |
ACSL5,SHOC2,SMC3,PDCD4,SMNDC1,VTI1A |
| 2.494e-02 | -3.69 | non-canonical Wnt signaling pathway | biological process | GO:0035567 | 138 | 30 | 17256 | 2622 |
PPP3CA,RHOA,CELSR2,PSMA8,RAC1,AGO2,PSMB7,PSMA1,PPP3CB,ZNRF3,PSMB9,PSMD9,FZD6,PSMB3,PSMC4,PSMD2,PSMA6,PSMD1,CDC42,RPS27A,PSMD8,PSMD3,PPP3R1,AP2B1,DVL1,SMURF1,ARRB2,AP2S1,PSMC1,DVL2 |
| 2.495e-02 | -3.69 | Prolactin signaling pathway | KEGG pathways | hsa04917 | 70 | 18 | 7161 | 1149 |
NRAS,AKT2,RAF1,KRAS,MAPK14,FOXO3,MAP2K2,MAPK3,SOCS7,SHC1,PIK3R2,SOCS6,SOCS4,STAT1,STAT3,MAPK1,HRAS,SOCS5 |
| 2.495e-02 | -3.69 | Prolactin signaling pathway | KEGG pathways | ko04917 | 70 | 18 | 7161 | 1149 |
NRAS,AKT2,RAF1,KRAS,MAPK14,FOXO3,MAP2K2,MAPK3,SOCS7,SHC1,PIK3R2,SOCS6,SOCS4,STAT1,STAT3,MAPK1,HRAS,SOCS5 |
| 2.496e-02 | -3.69 | CHARAFE_BREAST_CANCER_LUMINAL_VS_BASAL_UP | MSigDB lists | CHARAFE_BREAST_CANCER_LUMINAL_VS_BASAL_UP | 340 | 65 | 17377 | 2626 |
USP7,ZNF296,SNX27,ASH1L,ABCA3,UBN1,ARID2,KIAA0232,SLC25A44,SEC16A,MYEF2,RNF103,HNRNPA2B1,CYHR1,STRBP,TTC3,CHTOP,GPD1L,SCYL3,PCBP2,BAZ2A,KIAA0040,PGGT1B,CRNKL1,CIRBP,ABHD11,CADM1,CERS6,LUC7L3,SH3GLB2,CANT1,CSNK1D,DDX42,ANKRD13D,LZTR1,MIF4GD,ANXA6,GGA1,NACA,ARFIP2,SECISBP2,RSAD1,REEP5,GART,SLC1A4,SLC38A10,NDUFS8,TNRC18,SLC35A1,TRAPPC9,ZNF84,NUDT4,USP42,C14orf132,API5,RHOB,MAGED2,PTPRF,GNA12,POLE,SERF2,MEGF9,ZMIZ1,TOB1,C7orf26 |
| 2.502e-02 | -3.69 | BIRC3 (baculoviral IAP repeat containing 3) | protein interactions | 330 | 99 | 24 | 17029 | 2761 |
USP7,UBE2D3,NCOR2,BIRC3,TNFAIP3,RAF1,WDR1,UBXN1,XIAP,WDR82,UBE2V1,UBE2I,CYFIP2,BIRC2,IRF5,UBE2Q2,BIRC5,TANK,FBXO7,E2F1,TRIM32,MAVS,HTRA2,PACS2 |
| 2.502e-02 | -3.69 | FLOT1 (flotillin 1) | protein interactions | 10211 | 99 | 24 | 17029 | 2761 |
RPS15,COX15,RAB7A,MYH9,GORASP2,AURKB,CAPZA2,MYEF2,APP,PICALM,NPLOC4,GOLM1,MRPL50,MRPL55,FAM3C,SEL1L,ACAT1,YBX1,CHMP4B,ATP5F1A,ECPAS,ABCA1,ABCC1,PTOV1 |
| 2.502e-02 | -3.69 | GO_HISTONE_UBIQUITINATION | MSigDB lists | GO_HISTONE_UBIQUITINATION | 34 | 10 | 17377 | 2626 |
PAF1,HUWE1,SUZ12,UBR2,CTR9,USP22,PCGF1,CDC73,DDB1,RYBP |
| 2.502e-02 | -3.69 | GCM_BCL2L1 | MSigDB lists | GCM_BCL2L1 | 34 | 10 | 17377 | 2626 |
KDM3B,BRPF3,BAZ2A,CS,TNPO2,BCL2L1,CHTOP,PRKRA,FOXO3,AAAS |
| 2.502e-02 | -3.69 | WENDT_COHESIN_TARGETS_UP | MSigDB lists | WENDT_COHESIN_TARGETS_UP | 34 | 10 | 17377 | 2626 |
MKLN1,PFDN4,GOLGA8A,CAST,OXR1,FUT8,SREK1,TOP2B,MEF2A,SEPT7 |
| 2.503e-02 | -3.69 | trans-Golgi Network Vesicle Budding | REACTOME pathways | R-HSA-199992 | 73 | 19 | 10287 | 1696 |
CHMP2A,FTL,SNX2,TGOLN2,ARF1,AP1B1,AP4E1,AP3S1,PICALM,APP,TFRC,GNS,HGS,SNAP23,DNM2,AP1M1,AP1S1,CLTB,SNAPIN |
| 2.503e-02 | -3.69 | Clathrin derived vesicle budding | REACTOME pathways | R-HSA-421837 | 73 | 19 | 10287 | 1696 |
CHMP2A,FTL,SNX2,TGOLN2,ARF1,AP1B1,AP4E1,AP3S1,PICALM,APP,TFRC,GNS,HGS,SNAP23,DNM2,AP1M1,AP1S1,CLTB,SNAPIN |
| 2.505e-02 | -3.69 | TRAF2 (TNF receptor associated factor 2) | protein interactions | 7186 | 345 | 70 | 17029 | 2761 |
USP7,CYLD,WDYHV1,XIAP,IRF3,SEC16A,BECN1,RCOR3,BIRC2,RAD23A,NRF1,USF1,CDC42,SIVA1,PIN1,CDKN1B,MAST2,MAVS,DVL2,HTRA2,UBQLN4,PPP1R18,BIRC3,LNX2,ATXN1,UBE2V1,CHMP2B,RHEB,SRSF1,NECAP2,FBXO28,TAB2,SPATA2,UBXN2B,TICAM1,SMG9,SMURF1,TRAF5,USP53,RHEBL1,HIVEP3,EWSR1,MAPRE1,DNAJB2,CDCA3,IP6K2,CFLAR,FAM192A,PTPN2,SNRNP25,IRF4,PPP4R1,TANK,FBXO7,MAP3K14,MVP,PACS2,TNFAIP3,RB1CC1,ZMYND11,GORASP2,RAB3IP,NFATC2IP,APPL1,FADD,QARS,NFIL3,PIAS2,SIAH2,MAP3K5 |
| 2.507e-02 | -3.69 | Ubiquitin Mediated Degradation of Phosphorylated Cdc25A | REACTOME pathways | R-HSA-69601 | 54 | 15 | 10287 | 1696 |
PSMD2,PSMD1,PSMA6,PSMA8,RPS27A,PSMD8,PSMD3,PSMB7,PSMA1,CHEK2,PSMB9,PSMD9,PSMC1,PSMB3,PSMC4 |
| 2.507e-02 | -3.69 | p53-Independent G1/S DNA damage checkpoint | REACTOME pathways | R-HSA-69613 | 54 | 15 | 10287 | 1696 |
PSMD2,PSMD1,PSMA6,PSMA8,RPS27A,PSMD8,PSMD3,PSMB7,PSMA1,CHEK2,PSMB9,PSMD9,PSMC1,PSMB3,PSMC4 |
| 2.507e-02 | -3.69 | p53-Independent DNA Damage Response | REACTOME pathways | R-HSA-69610 | 54 | 15 | 10287 | 1696 |
PSMD2,PSMD1,PSMA6,PSMA8,RPS27A,PSMD8,PSMD3,PSMB7,PSMA1,CHEK2,PSMB9,PSMD9,PSMC1,PSMB3,PSMC4 |
| 2.507e-02 | -3.69 | Mitochondrial biogenesis | REACTOME pathways | R-HSA-1592230 | 54 | 15 | 10287 | 1696 |
PRKAB1,NRF1,MTERF1,GABPA,TWNK,CYCS,NCOA1,MEF2D,ATP5F1B,CREB1,MAPK14,POLG2,ATF2,NCOA2,CARM1 |
| 2.508e-02 | -3.69 | mucinous_carcinoma | COSMIC cancer mutations | mucinous_carcinoma | 460 | 84 | 17385 | 2587 |
TP53RK,DNMT3A,TSC2,NF1,RPS6KA1,RAF1,CSNK2A1,SMARCA4,PRKACA,TWF2,LYN,MAPK14,EEF2K,CDK5,ABL2,PDK2,PRKD3,NEK6,SCYL3,CDK12,SRPK2,PLK1,PLK3,NRAS,BRD4,AKT2,PBK,TLK1,MAP4K4,PKMYT1,BRCA1,AURKB,STK17B,TRIM28,MAP3K4,JAK1,CLK3,STK38,HIPK2,LIMK1,FASTK,STK11,RNASEL,CHEK2,MAPK1,SMAD4,PRPF4B,SCYL1,TRIO,PRKAA1,CDK13,ADCK5,EIF2AK4,CSNK1A1,SCYL2,FGFR3,RB1,PTEN,DAPK1,PHKG2,CAMK2G,CSNK1G3,MSH6,PDPK1,CSNK1G2,NEK7,EIF2AK1,MAP4K3,KRAS,ARID1A,MARK2,MAP2K2,DAPK3,MAPK3,MASTL,GNAS,MAPK6,MAP3K5,CDK2,RPS6KC1,HIPK3,HRAS,NRBP1,CDKN2A |
| 2.511e-02 | -3.68 | PNKD (paroxysmal nonkinesigenic dyskinesia) | protein interactions | 25953 | 94 | 23 | 17029 | 2761 |
GOLPH3L,TSC2,PBXIP1,BTAF1,ASAH1,DCUN1D5,AP1B1,APP,CIP2A,MAPK3,SCARB2,KIF14,NUP107,DCAF11,TNPO2,TAF12,ECD,PPP6R2,NUP85,PPP6R1,MYL12B,EYA2,FDFT1 |
| 2.511e-02 | -3.68 | HLA-DPA1 (major histocompatibility complex, class II, DP alpha 1) | protein interactions | 3113 | 94 | 23 | 17029 | 2761 |
GLT8D1,GOLIM4,NF1,ASPM,B4GALT5,ATP2C1,ABCB10,MYO9B,MTX1,TAF6L,B4GALT4,QSOX2,HLA-A,TMEM201,NUCB1,NUS1,INTS7,TYW5,SLC38A10,CLU,SCARB1,B4GALT3,NDUFA3 |
| 2.513e-02 | -3.68 | PTPRN (protein tyrosine phosphatase, receptor type N) | protein interactions | 5798 | 89 | 22 | 17029 | 2761 |
PPIB,UBQLN4,PRKCSH,C19orf25,DNAAF5,ADPGK,CMTM6,BZW2,CIP2A,NCDN,EIF3K,CAPN2,NUP210,SEC61A1,DDOST,KIF14,LTN1,TNPO3,RPN2,PLOD3,PDIA6,CLN6 |
| 2.513e-02 | -3.68 | PPP2R2A (protein phosphatase 2 regulatory subunit Balpha) | protein interactions | 5520 | 89 | 22 | 17029 | 2761 |
CCT2,IER2,PPP3CA,RAF1,CUL3,MCM2,CCT8,WWP2,DERL1,PPP2CA,RRN3,CDCA4,C1orf131,PPME1,WDR4,PTAR1,FAM122A,CRY2,CHEK2,PTPDC1,SMURF1,PPP2R2D |
| 2.515e-02 | -3.68 | oxaloacetate metabolic process | biological process | GO:0006107 | 12 | 5 | 17256 | 2622 |
MDH1,NIT2,GOT2,MDH2,ACLY |
| 2.515e-02 | -3.68 | negative regulation of autophagosome assembly | biological process | GO:1902902 | 12 | 5 | 17256 | 2622 |
CHMP4B,CHMP4A,FEZ2,PHF23,BECN1 |
| 2.515e-02 | -3.68 | 2'-deoxyribonucleotide biosynthetic process | biological process | GO:0009265 | 12 | 5 | 17256 | 2622 |
DCTD,GUK1,DUT,HDDC2,TBPL1 |
| 2.515e-02 | -3.68 | early endosome to Golgi transport | biological process | GO:0034498 | 12 | 5 | 17256 | 2622 |
SNX8,RAB6A,LMAN1,SURF4,SNX2 |
| 2.515e-02 | -3.68 | calcineurin-NFAT signaling cascade | biological process | GO:0033173 | 12 | 5 | 17256 | 2622 |
NFATC2,PPP3CA,NFATC3,PPP3CB,PPP3R1 |
| 2.515e-02 | -3.68 | pinocytosis | biological process | GO:0006907 | 12 | 5 | 17256 | 2622 |
EHD4,PPT1,MAPKAPK3,CARMIL1,DNM2 |
| 2.515e-02 | -3.68 | negative regulation of transcription from RNA polymerase II promoter in response to stress | biological process | GO:0097201 | 12 | 5 | 17256 | 2622 |
SIRT2,DNAJB1,CITED2,NCK1,VHL |
| 2.515e-02 | -3.68 | pyrimidine nucleoside salvage | biological process | GO:0043097 | 12 | 5 | 17256 | 2622 |
UPRT,UCK1,TK1,DCK,UCK2 |
| 2.515e-02 | -3.68 | signal transduction involved in G2 DNA damage checkpoint | biological process | GO:0072425 | 12 | 5 | 17256 | 2622 |
DTL,PLK1,BABAM2,BRCA1,BABAM1 |
| 2.515e-02 | -3.68 | alpha-beta T cell lineage commitment | biological process | GO:0002363 | 12 | 5 | 17256 | 2622 |
BCL2,IRF4,RHOA,STAT3,STAT6 |
| 2.515e-02 | -3.68 | deoxyribose phosphate biosynthetic process | biological process | GO:0046385 | 12 | 5 | 17256 | 2622 |
DCTD,GUK1,DUT,HDDC2,TBPL1 |
| 2.515e-02 | -3.68 | glycosphingolipid catabolic process | biological process | GO:0046479 | 12 | 5 | 17256 | 2622 |
GALC,GM2A,NEU1,HEXB,GBA |
| 2.516e-02 | -3.68 | PRKCD (protein kinase C delta) | protein interactions | 5580 | 161 | 36 | 17029 | 2761 |
TRIM41,ADD1,RAF1,RAC1,HABP4,TKT,LYN,APP,FAM192A,SHC1,GRK2,IL6ST,PTGES3,STAT3,ADCY7,PDPK1,CYTH1,TRAPPC13,PRKDC,VHL,ADRB2,BUD13,FXR1,MACF1,MAPK3,PPP2CA,GNA12,HSPA4,DHX16,STAT1,ADAM9,ACTB,YWHAZ,MAPK1,NUMB,PRPF4B |
| 2.516e-02 | -3.68 | GSE1460_CD4_THYMOCYTE_VS_THYMIC_STROMAL_CELL_UP | MSigDB lists | GSE1460_CD4_THYMOCYTE_VS_THYMIC_STROMAL_CELL_UP | 178 | 37 | 17377 | 2626 |
SEPHS2,PRKAB1,CERK,CUL1,IL21R,PCYOX1L,CEP104,NDUFV1,RIMS3,XRCC2,XPA,MSH2,RNF19A,TRIM14,SPSB3,SNRNP200,TRAPPC9,CELSR2,AATF,TAOK1,MFNG,PPWD1,PLEC,CBFB,ERC1,POLR2A,IRF5,ZNF862,OSBPL8,SAFB,STAT6,XRCC3,NCOA1,NDE1,NGLY1,BRD9,PTDSS1 |
| 2.516e-02 | -3.68 | GSE5503_MLN_DC_VS_PLN_DC_ACTIVATED_ALLOGENIC_TCELL_UP | MSigDB lists | GSE5503_MLN_DC_VS_PLN_DC_ACTIVATED_ALLOGENIC_TCELL_UP | 178 | 37 | 17377 | 2626 |
GCLM,NAT9,PIGM,DEPDC1,TRIP10,GORASP1,SNX15,TPX2,KIF23,RACGAP1,KIF2C,APP,CCNA2,MED8,MRPL34,RNF5,RHOBTB3,TNFAIP3,RBX1,PRRC2A,OAF,BTG2,CDCA2,OTUD3,DAPK3,RAD54B,MASTL,KIF18B,TWSG1,NEIL3,ZC3H7B,COX8A,EXOC4,BAZ1B,ST3GAL2,REEP4,HIGD2A |
| 2.516e-02 | -3.68 | GSE36476_YOUNG_VS_OLD_DONOR_MEMORY_CD4_TCELL_72H_TSST_ACT_DN | MSigDB lists | GSE36476_YOUNG_VS_OLD_DONOR_MEMORY_CD4_TCELL_72H_TSST_ACT_DN | 178 | 37 | 17377 | 2626 |
KIF3B,ANKRD27,PRKAB1,NAT9,MAGEH1,PNISR,TRIP10,MANBA,BTN3A1,ZFYVE21,ARGLU1,IL21R,MAP1LC3B,RSAD1,PDCD2,DCP1A,NFU1,PIK3IP1,TFG,MAML1,OGG1,SUGP2,PARP4,ZBED5,HEBP2,METTL22,PDE3B,STX16,EIF3H,NSA2,RBM47,RPS14,GOLGA8A,MEGF9,RBPJ,N4BP2L2,CWC25 |
| 2.516e-02 | -3.68 | GSE9988_ANTI_TREM1_VS_LPS_MONOCYTE_DN | MSigDB lists | GSE9988_ANTI_TREM1_VS_LPS_MONOCYTE_DN | 178 | 37 | 17377 | 2626 |
ZBTB10,GPR132,PLXNC1,UGP2,SESTD1,PPP1R15B,SLC25A12,CREBL2,CCNB1,EIF1B,BIRC2,CFLAR,RBM17,RAB21,CLIC4,PSMA6,ITGB8,TNFAIP8,SNX18,FJX1,TANK,RCSD1,FOXN2,PLK3,GTF3C6,BIRC3,TNFAIP3,ANKRD33B,PFKFB3,DNAJA1,PTTG1IP,PLEKHF2,C1orf122,MAP3K4,TAB2,OAZ2,ZC3HAV1 |
| 2.516e-02 | -3.68 | GSE45739_NRAS_KO_VS_WT_ACD3_ACD28_STIM_CD4_TCELL_DN | MSigDB lists | GSE45739_NRAS_KO_VS_WT_ACD3_ACD28_STIM_CD4_TCELL_DN | 178 | 37 | 17377 | 2626 |
MAX,PPCS,CENPF,TIA1,BTN3A1,RACGAP1,SIKE1,ETS1,STAM,ATPAF1,ANKRD28,DECR1,ZNF260,TMEM99,BRI3,ANKRD13C,GM2A,PCBP2,KDELR1,YTHDC1,TRAFD1,HMGN5,RB1CC1,PBXIP1,PARP4,C14orf132,RTF1,FXR1,C9orf40,AMZ2,CCDC86,NSMCE2,OAZ2,TFDP2,IGBP1,PDCD4,RNF114 |
| 2.523e-02 | -3.68 | Homology Directed Repair | REACTOME pathways | R-HSA-5693538 | 138 | 32 | 10287 | 1696 |
CLSPN,SUMO2,BABAM1,RMI2,BLM,UBE2I,RMI1,RPA2,PCNA,CCNA2,BABAM2,XRCC2,TIMELESS,SPIDR,ERCC1,RFC3,POLK,RAD51AP1,TOP3A,BRCA1,RFC2,RPA1,RAD51C,POLE,PALB2,RPS27A,H2AFX,XRCC3,GEN1,CDK2,RAD51D,POLQ |
| 2.524e-02 | -3.68 | transferase activity, transferring acyl groups other than amino-acyl groups | molecular function | GO:0016747 | 220 | 45 | 17224 | 2647 |
GNPNAT1,ZDHHC8,AGPAT1,AGPAT3,TAF6L,WDR5,SUPT7L,LCLAT1,CRAT,ZDHHC13,NAA50,HADHB,TAF5L,KANSL2,SPTSSA,ATF2,LPCAT1,SMARCE1,NAA35,ELOVL5,ZDHHC18,KAT2A,KAT7,ELP4,USP22,EDF1,TAZ,ZDHHC3,NMT2,ABHD5,GOLGA7,AGPAT2,CERS6,TEX30,LPCAT4,OGT,ACAT1,ZDHHC7,MBOAT1,TAF12,NCOA1,NAA20,OSGEPL1,SAT2,NAA60 |
| 2.524e-02 | -3.68 | - | gene3d domains | 1.10.580.10 | 2 | 2 | 8148 | 1295 |
CS,ACLY |
| 2.524e-02 | -3.68 | - | gene3d domains | 3.90.80.10 | 2 | 2 | 8148 | 1295 |
PPA1,PPA2 |
| 2.524e-02 | -3.68 | - | gene3d domains | 2.60.120.470 | 2 | 2 | 8148 | 1295 |
TXNL1,PITHD1 |
| 2.524e-02 | -3.68 | - | gene3d domains | 1.10.720.110 | 2 | 2 | 8148 | 1295 |
SAP30L,SAP30 |
| 2.524e-02 | -3.68 | - | gene3d domains | 1.10.10.540 | 2 | 2 | 8148 | 1295 |
RAD23B,RAD23A |
| 2.524e-02 | -3.68 | - | gene3d domains | 2.60.40.1150 | 2 | 2 | 8148 | 1295 |
AP2B1,AP1B1 |
| 2.524e-02 | -3.68 | - | gene3d domains | 1.10.230.10 | 2 | 2 | 8148 | 1295 |
CS,ACLY |
| 2.524e-02 | -3.68 | - | gene3d domains | 3.90.530.10 | 2 | 2 | 8148 | 1295 |
SLC30A9,XPA |
| 2.524e-02 | -3.68 | - | gene3d domains | 1.10.760.10 | 2 | 2 | 8148 | 1295 |
CYCS,CYC1 |
| 2.524e-02 | -3.68 | - | gene3d domains | 1.25.40.210 | 2 | 2 | 8148 | 1295 |
TERF1,TERF2 |
| 2.524e-02 | -3.68 | - | gene3d domains | 1.10.720.150 | 2 | 2 | 8148 | 1295 |
PRPF4,PRPF18 |
| 2.524e-02 | -3.68 | - | gene3d domains | 1.10.10.1410 | 2 | 2 | 8148 | 1295 |
RPLP2,RPLP1 |
| 2.524e-02 | -3.68 | - | gene3d domains | 1.20.1250.40 | 2 | 2 | 8148 | 1295 |
CRCP,POLR2D |
| 2.524e-02 | -3.68 | - | gene3d domains | 2.40.240.10 | 2 | 2 | 8148 | 1295 |
EPRS,QARS |
| 2.524e-02 | -3.68 | - | gene3d domains | 3.40.50.12190 | 2 | 2 | 8148 | 1295 |
TOR1AIP2,TOR1AIP1 |
| 2.524e-02 | -3.68 | ATGCAGT,MIR-217 | MSigDB lists | ATGCAGT,MIR-217 | 106 | 24 | 17377 | 2626 |
YTHDC1,HIVEP3,UBL3,MIOS,IVNS1ABP,TACC1,EHMT1,TM9SF3,KRAS,RTF1,MYEF2,RBM38,HNRNPA2B1,SLC31A1,PCNA,STRBP,STT3A,LUC7L3,ZCCHC2,OGT,PDS5B,MAPK1,MTPN,DYNC1LI2 |
| 2.540e-02 | -3.67 | V$WHN_B | MSigDB lists | V$WHN_B | 241 | 48 | 17377 | 2626 |
OTUD5,H2AFZ,ZCCHC9,TMEM203,NF1,ZNF768,ZBTB37,TSC22D3,SF3B1,ANKH,DBF4,CTCF,HAUS4,SND1,SLC20A1,GGPS1,RAB11A,CSDE1,TFAP4,DLG5,ARPC5,MTMR4,UCHL5,FIZ1,CCAR1,ZNF524,PPP3CA,AMD1,MRPL12,SREK1,GALK2,TOMM40,PCGF1,ARMC8,POLR2A,SUPT16H,DDX17,VEZF1,NSF,HNRNPH3,PITPNA,DDX5,PRPF4,RGL1,H3F3A,NUDT11,ZBTB11,TOB1 |
| 2.552e-02 | -3.67 | regulation of telomere maintenance | biological process | GO:0032204 | 79 | 19 | 17256 | 2622 |
USP7,CCT2,ERCC1,NEK7,AURKB,PARN,CCT8,MAPK3,XRCC5,TERF2IP,HNRNPA2B1,MAP3K4,UPF1,PML,NABP2,MAPK1,TERF1,POT1,TERF2 |
| 2.552e-02 | -3.67 | regulation of protein targeting | biological process | GO:1903533 | 79 | 19 | 17256 | 2622 |
UBE2D3,ATP5IF1,AKT2,PRKAA1,ANK3,CIB1,SH3GLB1,USP36,PRNP,MIEF1,CDK5,NUCB1,HUWE1,PARL,ATG13,LMAN1,C2CD5,HTRA2,CHP1 |
| 2.556e-02 | -3.67 | POT1 (protection of telomeres 1) | protein interactions | 25913 | 209 | 45 | 17029 | 2761 |
RPS2,TRIP10,CCM2,ENSA,YTHDF3,THRAP3,DNAJB1,TWF2,PCBP1,CPNE3,TERF2IP,MDM2,SH3BP1,RPAP1,ABCD1,AHCY,CORO1A,MVP,CFL1,EEF1D,TERF2,NUDC,PDLIM2,SPTAN1,LDHB,AMPD2,PRKDC,LDHA,EIF3G,RPSA,NCDN,DPYSL3,NAP1L1,PEX5,AHNAK,MAP4,APPL2,ATXN2L,PRMT7,DNPH1,ACTB,WIPI2,TERF1,POT1,PFKP |
| 2.559e-02 | -3.67 | GSE13887_RESTING_VS_ACT_CD4_TCELL_DN | MSigDB lists | GSE13887_RESTING_VS_ACT_CD4_TCELL_DN | 117 | 26 | 17377 | 2626 |
SRP72,CDKN2AIP,RPL29,PRKAB1,ABHD2,SARNP,MAN1B1,HNRNPF,LNX2,CBFA2T2,CHMP2B,MAPK14,IRF5,NSA2,TERF2IP,CCNK,MAN2A2,SUB1,ETS2,ITGB8,MAPK6,KBTBD7,ARRDC1,FAM126A,AHCYL1,SEH1L |
| 2.559e-02 | -3.67 | CHIARADONNA_NEOPLASTIC_TRANSFORMATION_CDC25_UP | MSigDB lists | CHIARADONNA_NEOPLASTIC_TRANSFORMATION_CDC25_UP | 117 | 26 | 17377 | 2626 |
SEPHS2,IVNS1ABP,PSPC1,EMB,SRSF6,MAGED1,ANK3,EIF2AK4,RAB11A,SRRT,NAP1L1,PTEN,ATP13A3,FAM3C,TPST1,PGRMC1,H2AFX,SLC16A1,ANP32E,RBM3,SRSF3,SLC12A2,CCNB2,F2R,MYL12B,IFI16 |
| 2.559e-02 | -3.67 | IZADPANAH_STEM_CELL_ADIPOSE_VS_BONE_UP | MSigDB lists | IZADPANAH_STEM_CELL_ADIPOSE_VS_BONE_UP | 117 | 26 | 17377 | 2626 |
ACSL5,SNX8,MAPRE2,GOLIM4,NQO1,LAP3,SLC41A1,SRGN,UCK2,DDX39A,PSMB9,ODC1,LYRM2,LYN,ETS1,LMNA,HLA-B,NEK6,PPP4R1,ORAI1,PDXK,MAP3K5,NR2F2,LRP8,TSPAN5,PTPRK |
| 2.560e-02 | -3.67 | GO_N_METHYLTRANSFERASE_ACTIVITY | MSigDB lists | GO_N_METHYLTRANSFERASE_ACTIVITY | 69 | 17 | 17377 | 2626 |
ASH1L,HEMK1,CXXC1,EHMT1,WDR82,EZH1,MEN1,WDR5,PRMT2,DOT1L,IRF4,SUV39H2,SETD3,CAMKMT,PRMT7,FBL,CARM1 |
| 2.564e-02 | -3.66 | HMG | smart domains | SM00398 | 51 | 13 | 9493 | 1367 |
UBTF,SP100,CIC,HMGXB3,BBX,WDHD1,HMGB2,PBRM1,KMT2C,SOX4,SMARCE1,HMG20A,SSRP1 |
| 2.567e-02 | -3.66 | intrinsic component of endoplasmic reticulum membrane | cellular component | GO:0031227 | 153 | 32 | 18223 | 2701 |
HLA-E,TAP1,SLC35B2,SLC35B1,BCAP31,HLA-A,RHBDD1,SPPL2A,RRBP1,SLC35B4,PIGG,ARL6IP1,ZFYVE27,TAP2,TECR,PREB,ANKLE2,ELOVL5,PIGT,ESYT1,SYVN1,SPPL2B,DERL1,HLA-B,SEC61A1,SARAF,SAMD8,ATF6,PKD2,CLN3,TMEM33,ESYT2 |
| 2.568e-02 | -3.66 | GO_NEGATIVE_REGULATION_OF_SEQUENCE_SPECIFIC_DNA_BINDING_TRANSCRIPTION_FACTOR_ACTIVITY | MSigDB lists | GO_NEGATIVE_REGULATION_OF_SEQUENCE_SPECIFIC_DNA_BINDING_TRANSCRIPTION_FACTOR_ACTIVITY | 128 | 28 | 17377 | 2626 |
USP7,CYLD,TNFAIP3,PHB2,DAP,EIF2AK4,MEN1,PRMT2,MAD2L2,FZD6,PRNP,WWP2,CAT,BRMS1,RB1,KEAP1,SP100,GLIS2,SIVA1,CEBPG,NLRC5,PIAS2,ARRB2,PARP10,CDKN2A,HDAC2,EGLN1,RLIM |
| 2.573e-02 | -3.66 | GSE13946_CTRL_VS_DSS_COLITIS_GD_TCELL_FROM_COLON_UP | MSigDB lists | GSE13946_CTRL_VS_DSS_COLITIS_GD_TCELL_FROM_COLON_UP | 167 | 35 | 17377 | 2626 |
SYS1,FAM129A,SRGN,PTTG1,CUTA,CHCHD2,PAWR,SDF2L1,OAT,RGS2,AP3S1,REEP5,RGS1,SUB1,F2R,DDX28,ELL2,NUDT4,COQ10B,SCFD2,HTATIP2,ODC1,RHEB,ECH1,MYO1F,ABHD5,AHNAK,RBM47,NFIL3,GADD45B,COX8A,ITGB1,ATF6,BTF3,SMNDC1 |
| 2.573e-02 | -3.66 | GSE5099_MONOCYTE_VS_ALTERNATIVE_M2_MACROPHAGE_DN | MSigDB lists | GSE5099_MONOCYTE_VS_ALTERNATIVE_M2_MACROPHAGE_DN | 167 | 35 | 17377 | 2626 |
SNX27,DNAJB2,DYNLL1,RAB6A,RUFY1,LYRM2,PAIP1,MAT2B,CRKL,HNRNPA2B1,TET3,CEP104,CCNA2,ATP2A2,SSBP3,STRAP,ARL5A,HEMK1,ANKRD37,SLC26A6,LRRC1,STYXL1,EIF4G2,SERP1,SMAP2,GEMIN5,KPNA4,DSN1,RAB24,OSBPL8,SAFB,CLN3,APOL2,EGLN1,LRCH1 |
| 2.573e-02 | -3.66 | TRIM23 (tripartite motif containing 23) | protein interactions | 373 | 156 | 35 | 17029 | 2761 |
UBE2D3,COX5B,UBE2E2,FAM208B,PKP4,GGA2,UBE2I,FLAD1,MDM2,NEK6,SIAH1,PPIL2,PIK3R2,JOSD1,NFU1,RBM15B,CYTH1,PPP1R18,TNFAIP3,SNRPB,MTFR2,PSMA1,EAF2,USP21,TRIM28,RAD18,FAM110A,PITX1,PIAS2,USP20,SMG9,KLHL42,TRIM32,NXT2,ZNF564 |
| 2.573e-02 | -3.66 | tRNA methyltransferase complex | cellular component | GO:0043527 | 5 | 3 | 18223 | 2701 |
METTL1,TRMT6,WDR4 |
| 2.573e-02 | -3.66 | nuclear stress granule | cellular component | GO:0097165 | 5 | 3 | 18223 | 2701 |
TIA1,SYMPK,DHX9 |
| 2.573e-02 | -3.66 | annulate lamellae | cellular component | GO:0005642 | 5 | 3 | 18223 | 2701 |
EIF5A,NUP62,BICD2 |
| 2.573e-02 | -3.66 | BRISC complex | cellular component | GO:0070552 | 5 | 3 | 18223 | 2701 |
BABAM2,ABRAXAS2,BABAM1 |
| 2.573e-02 | -3.66 | Cul4B-RING E3 ubiquitin ligase complex | cellular component | GO:0031465 | 5 | 3 | 18223 | 2701 |
DTL,RBX1,DDB1 |
| 2.573e-02 | -3.66 | chromosome passenger complex | cellular component | GO:0032133 | 5 | 3 | 18223 | 2701 |
AURKB,BIRC5,CDCA8 |
| 2.573e-02 | -3.66 | DNA replication preinitiation complex | cellular component | GO:0031261 | 5 | 3 | 18223 | 2701 |
GINS1,ORC3,GINS4 |
| 2.575e-02 | -3.66 | regulation of cytoskeleton organization | biological process | GO:0051493 | 505 | 93 | 17256 | 2622 |
WASF2,RHOG,CHMP2A,SKA3,PDCD6IP,CYLD,ADD1,POC1A,RAC1,ACTR3,TPX2,STMN1,TWF2,CDK5,ABL2,CDC42,SH3BP1,CDKN1B,CORO1A,MTPN,CARMIL1,CFL1,TACC3,DCTN1,MLST8,PLK1,ARHGAP17,RHOBTB3,PSRC1,NCK1,TAOK1,GMFB,WIPF1,EZR,ARHGDIB,BICD2,BRCA1,CCNF,CHMP2B,WAS,MID1IP1,LIMK1,CHMP4B,XRCC3,ROCK1,GEN1,MAPK1,SMAD4,MAPRE1,GMFG,MECP2,RAE1,RHOC,PRKAA1,CDK2AP2,CIB1,ARFIP2,ARF1,NCKAP1,RGS2,JMY,SPAG5,CAPN2,PDXP,VASP,CLIC4,SMC3,ARPC5,CENPJ,CAPZA1,ARHGEF2,MCPH1,SPTAN1,TGFB1,CYFIP1,RHOA,KAT2A,WDR1,CAMSAP1,CAPZA2,ARPC1A,BORA,KIF11,MARK2,RHOB,DAPK3,MAPK3,HSPA1B,TSC1,KIF18A,ARAP1,NUP62,HRAS |
| 2.576e-02 | -3.66 | GO_ACTIVATION_OF_IMMUNE_RESPONSE | MSigDB lists | GO_ACTIVATION_OF_IMMUNE_RESPONSE | 382 | 72 | 17377 | 2626 |
WASF2,CYLD,RAF1,ACTR3,RAC1,CUL1,IRF3,PRKACA,LYN,BIRC2,VAV1,PSMD1,PSMA6,CDC42,PIK3R2,MAVS,ABI1,NRAS,BIRC3,PSMA8,NCK1,PSMB7,WIPF1,UBE2V1,NFATC2,PSMB9,STOML2,WAS,TAB2,RPS27A,PSMD8,LIMK1,PSMD3,STK11,TICAM1,ACTB,CLU,MAPK1,PSMC1,DDX58,UBE2D3,LIME1,VAV2,BTN3A1,NCKAP1,PSMD9,PSEN1,PSMD2,CTSS,PTEN,ARPC5,TANK,BCL2,CNPY3,PDPK1,CYFIP1,TNFAIP3,MAPKAPK3,DENND1B,PSMA1,KRAS,CYFIP2,ICAM2,ARPC1A,PSMB3,FADD,MAPK3,PSMC4,ELMO1,CSK,HRAS,IFI16 |
| 2.577e-02 | -3.66 | LCOR (ligand dependent nuclear receptor corepressor) | protein interactions | 84458 | 55 | 15 | 17029 | 2761 |
NOP9,USP7,DECR1,KPNA4,EWSR1,GOLGA2,BAZ2A,SUZ12,RBPJ,WDR76,NDE1,KLF6,MAPK14,NIPSNAP1,TFEB |
| 2.577e-02 | -3.66 | MAP3K4 (mitogen-activated protein kinase kinase kinase 4) | protein interactions | 4216 | 55 | 15 | 17029 | 2761 |
MAP3K4,USF1,SYNCRIP,CDC42,AXIN1,GADD45B,RAC1,GADD45G,PTPN11,TOP3A,KIF23,RACGAP1,YWHAZ,CNTROB,AP4E1 |
| 2.577e-02 | -3.66 | TRIP12 (thyroid hormone receptor interactor 12) | protein interactions | 9320 | 55 | 15 | 17029 | 2761 |
RPA2,USP7,VHL,MECP2,KBTBD7,EXOSC9,RP2,UBE4B,USP11,SMARCE1,CAPN1,IFI16,CDKN2A,RPA1,SRPK2 |
| 2.577e-02 | -3.66 | BPNT1 (3'(2'), 5'-bisphosphate nucleotidase 1) | protein interactions | 10380 | 55 | 15 | 17029 | 2761 |
NUDT19,MEMO1,TOP3A,FEM1B,MICU2,CDC6,MYO9B,RNASEH2A,MYO9A,GFM2,APOL2,NSUN4,ACSF2,RSAD1,PDF |
| 2.577e-02 | -3.66 | DDX47 (DEAD-box helicase 47) | protein interactions | 51202 | 55 | 15 | 17029 | 2761 |
CYLD,NOP2,NOL8,GTPBP4,TRA2B,CBWD1,KRAS,SRSF3,APP,POC5,IFI16,PRNP,RBM15B,CDC5L,CAND1 |
| 2.577e-02 | -3.66 | DPYSL2 (dihydropyrimidinase like 2) | protein interactions | 1808 | 55 | 15 | 17029 | 2761 |
UNK,HSPH1,RHOA,DPYSL2,DNAAF2,CDCA8,GORASP2,DNAJB1,ROCK1,XPO7,MCM2,CDK2,TUBB,NUMB,DPYSL3 |
| 2.577e-02 | -3.66 | NDUFB5 (NADH:ubiquinone oxidoreductase subunit B5) | protein interactions | 4711 | 55 | 15 | 17029 | 2761 |
NDUFS1,SYNCRIP,NDUFB6,TIMMDC1,NDUFA11,MRPS26,LAMTOR3,MPV17,ITM2A,NDUFB9,NDUFA4,NDUFS5,NDUFB1,NDUFS7,NDUFS4 |
| 2.579e-02 | -3.66 | sex chromosome | cellular component | GO:0000803 | 30 | 9 | 18223 | 2701 |
DNMT3A,H2AFZ,SUZ12,H2AFX,H2AFY,SMC6,H3F3A,CDK2,BIRC2 |
| 2.579e-02 | -3.66 | polysomal ribosome | cellular component | GO:0042788 | 30 | 9 | 18223 | 2701 |
RPL32,RPL6,DHX9,RPL38,RPL8,RPL19,RPS26,RPL36,RPL11 |
| 2.579e-02 | -3.66 | ADAM33 (ADAM metallopeptidase domain 33) | protein interactions | 80332 | 41 | 12 | 17029 | 2761 |
UBQLN4,TOR3A,TYW1,LRP5,SDF2L1,DHFR2,TTC17,ITGB5,ANKRD46,LMNA,HLA-A,PDF |
| 2.579e-02 | -3.66 | NUDT3 (nudix hydrolase 3) | protein interactions | 11165 | 41 | 12 | 17029 | 2761 |
CHCHD3,PRKD3,PEX5,RPL17,MCM5,RPLP1,ARL6IP1,RPL8,DNAJA1,ASB13,OAT,REEP5 |
| 2.579e-02 | -3.66 | REST (RE1 silencing transcription factor) | protein interactions | 5978 | 41 | 12 | 17029 | 2761 |
PLK1,SUB1,EIF4A3,PIN1,SCYL1,SMARCA4,RCOR1,FBXW2,MAPK1,SMARCE1,HDAC2,TERF2 |
| 2.579e-02 | -3.66 | PWP2 (PWP2, small subunit processome component) | protein interactions | 5822 | 41 | 12 | 17029 | 2761 |
TBL3,MECP2,ZNF746,CUL3,CUL1,TARDBP,FBL,RBM4,GPATCH4,IFI16,USP36,BYSL |
| 2.579e-02 | -3.66 | DOK2 (docking protein 2) | protein interactions | 9046 | 41 | 12 | 17029 | 2761 |
CRKL,SHC1,NCK1,COQ8A,CENPM,LYN,STAT3,APPL1,POT1,ASF1B,SSSCA1,CFLAR |
| 2.579e-02 | -3.66 | PABPN1 (poly(A) binding protein nuclear 1) | protein interactions | 8106 | 41 | 12 | 17029 | 2761 |
STAU1,PCNA,EWSR1,SUZ12,CUL3,CUL1,SMARCA4,BCLAF1,TARDBP,NKAPD1,CARM1,CAND1 |
| 2.579e-02 | -3.66 | PLA2G4A (phospholipase A2 group IVA) | protein interactions | 5321 | 41 | 12 | 17029 | 2761 |
MKNK1,CCNA2,JAK1,UBXN1,MYBL2,SIRT2,RUVBL2,CDK2,STAT3,MAPK14,MAPK1,MAPK3 |
| 2.579e-02 | -3.66 | RP2 (RP2, ARL3 GTPase activating protein) | protein interactions | 6102 | 41 | 12 | 17029 | 2761 |
TRIP12,TSC2,TBL3,TNPO3,TNPO2,OSTF1,KNTC1,XPO7,ECPAS,STAT3,SYMPK,CSNK1D |
| 2.579e-02 | -3.66 | CRIP1 (cysteine rich protein 1) | protein interactions | 1396 | 41 | 12 | 17029 | 2761 |
MIF,TK1,UFC1,DBI,ADSL,ACAT1,TAGLN2,PCBP1,CD81,CBFB,CFL1,FUBP1 |
| 2.584e-02 | -3.66 | NEK9 (NIMA related kinase 9) | protein interactions | 91754 | 32 | 10 | 17029 | 2761 |
MDM2,NEK6,HUWE1,NEK7,MCM5,DYNLL1,BICD2,SPDL1,SUPT16H,SSRP1 |
| 2.584e-02 | -3.66 | HP (haptoglobin) | protein interactions | 3240 | 32 | 10 | 17029 | 2761 |
SNX27,MAPK6,GADD45G,DDX31,ICE2,EXOSC9,MVP,VKORC1,MIS12,RPL11 |
| 2.584e-02 | -3.66 | KIF5A (kinesin family member 5A) | protein interactions | 3798 | 32 | 10 | 17029 | 2761 |
KIF5B,STAU1,TK1,VPS26B,PIN1,MAP4K4,KLC1,TP53BP2,KIF11,NCOA2 |
| 2.584e-02 | -3.66 | SNX21 (sorting nexin family member 21) | protein interactions | 90203 | 32 | 10 | 17029 | 2761 |
POLA2,CD3EAP,FAAP100,AMD1,CBWD1,ATG2B,EIF2A,TRIM65,APP,VPS13B |
| 2.584e-02 | -3.66 | TSN (translin) | protein interactions | 7247 | 32 | 10 | 17029 | 2761 |
PPP3CA,EIF4A3,SNX2,NSUN2,CTPS1,TTC4,ATP6V1C1,GIT2,STRAP,VPS29 |
| 2.584e-02 | -3.66 | C1D (C1D nuclear receptor corepressor) | protein interactions | 10438 | 32 | 10 | 17029 | 2761 |
NCOR2,EXOSC6,EXOSC7,NOL11,ZCCHC8,PRKDC,EXOSC1,UTP15,EXOSC9,APP |
| 2.584e-02 | -3.66 | UBLCP1 (ubiquitin like domain containing CTD phosphatase 1) | protein interactions | 134510 | 32 | 10 | 17029 | 2761 |
PSMD2,PSMD1,UCHL5,PSMD8,PSMD3,PRPSAP1,ZFAND5,PSMC1,TARS,PSMC4 |
| 2.584e-02 | -3.66 | WDR74 (WD repeat domain 74) | protein interactions | 54663 | 32 | 10 | 17029 | 2761 |
USP7,DDX47,NSUN2,RBM3,UBE3C,RGS2,RRS1,MAK16,IFI16,NUDT3 |
| 2.584e-02 | -3.66 | ACBD3 (acyl-CoA binding domain containing 3) | protein interactions | 64746 | 32 | 10 | 17029 | 2761 |
DUS3L,HARS,TBC1D22A,EFTUD2,PPIE,CUL3,TMEM216,GORASP2,SLC35A1,EVC2 |
| 2.584e-02 | -3.66 | DRAP1 (DR1 associated protein 1) | protein interactions | 10589 | 32 | 10 | 17029 | 2761 |
CDKN2C,TPD52L2,TK1,FEZ2,HSPBP1,DRAP1,RAD23B,APP,PLEKHF2,SRPK2 |
| 2.584e-02 | -3.66 | PLP2 (proteolipid protein 2) | protein interactions | 5355 | 32 | 10 | 17029 | 2761 |
MRPL9,SYNCRIP,DLGAP4,LAGE3,ILF3,HNRNPF,VKORC1,BCAP31,LMNA,MRPL57 |
| 2.584e-02 | -3.66 | ADCYAP1 (adenylate cyclase activating polypeptide 1) | protein interactions | 116 | 32 | 10 | 17029 | 2761 |
COPS8,GID8,NUCB1,GCC2,MKLN1,AMD1,PM20D2,GGPS1,ARMC8,CLNS1A |
| 2.584e-02 | -3.66 | LTV1 (LTV1 ribosome biogenesis factor) | protein interactions | 84946 | 32 | 10 | 17029 | 2761 |
RPS2,VHL,RPS14,POC1A,CSNK2A1,FTSJ3,APP,BYSL,RPSA,DCTN1 |
| 2.584e-02 | -3.66 | MAGEA4 (MAGE family member A4) | protein interactions | 4103 | 32 | 10 | 17029 | 2761 |
TK1,DCAF6,RAD18,TSPYL4,TIGD5,WBP2,FXR1,APP,POT1,HLA-A |
| 2.584e-02 | -3.66 | ANKRD52 (ankyrin repeat domain 52) | protein interactions | 283373 | 32 | 10 | 17029 | 2761 |
PLK1,FOXK1,PPP6C,USP10,DCLRE1C,PPP6R2,MOB1A,PPP6R3,PPP6R1,USP36 |
| 2.584e-02 | -3.66 | APPL2 (adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2) | protein interactions | 55198 | 32 | 10 | 17029 | 2761 |
TSC1,SUV39H2,MTA2,RUVBL2,KMT2C,CRLF3,POT1,RAB22A,APPL1,MLST8 |
| 2.584e-02 | -3.66 | TSTA3 (tissue specific transplantation antigen P35B) | protein interactions | 7264 | 32 | 10 | 17029 | 2761 |
MAT2B,PTPRF,SEC31A,PDCD6,STAT6,PPME1,RABIF,DNAJC9,KDM3A,GLRX3 |
| 2.584e-02 | -3.66 | Dtl (denticleless E3 ubiquitin protein ligase) | protein interactions | 76843 | 32 | 10 | 17029 | 2761 |
DTL,COPS8,CCT2,PCNA,COPS6,RBX1,CCT8,DDA1,DDB1,MLST8 |
| 2.584e-02 | -3.66 | TMPRSS3 (transmembrane serine protease 3) | protein interactions | 64699 | 32 | 10 | 17029 | 2761 |
KIF2A,TMED7,TMEM39A,PPP1R15B,TOR3A,TYW1,UPK3BL1,CISD2,PDE3B,HLA-A |
| 2.584e-02 | -3.66 | CBX7 (chromobox 7) | protein interactions | 23492 | 32 | 10 | 17029 | 2761 |
PHC2,SUV39H2,UCHL5,PCGF6,CSNK2A1,USP20,DDX5,UBE4A,PCGF1,HDAC2 |
| 2.584e-02 | -3.66 | MRPL27 (mitochondrial ribosomal protein L27) | protein interactions | 51264 | 32 | 10 | 17029 | 2761 |
MRPL50,MRPL9,MRPL42,MRPL39,KBTBD7,MRPL12,RPL6,CDK2,KIF11,APP |
| 2.584e-02 | -3.66 | DPYSL3 (dihydropyrimidinase like 3) | protein interactions | 1809 | 32 | 10 | 17029 | 2761 |
ST13,DPYSL2,DNAAF2,EYA1,MSH2,CDCA8,MCM2,CDK2,TERF1,POT1 |
| 2.584e-02 | -3.66 | INO80E (INO80 complex subunit E) | protein interactions | 283899 | 32 | 10 | 17029 | 2761 |
TFAP4,TNFAIP8,UCHL5,TCF3,PRKAA1,PSMA1,KPNA2,RUVBL2,YY1,APPL1 |
| 2.585e-02 | -3.66 | GSE2770_IL4_ACT_VS_ACT_CD4_TCELL_48H_UP | MSigDB lists | GSE2770_IL4_ACT_VS_ACT_CD4_TCELL_48H_UP | 184 | 38 | 17377 | 2626 |
HLA-E,RAC1,MEF2A,NKRF,SYNRG,EPM2A,NDUFS4,MOAP1,TFAP4,EIF2S2,SLC1A4,ATP2A2,CBWD2,IARS,GOT2,PTPN11,AFF1,FNIP2,SGCB,C12orf75,RPRD1B,RPP25,TMEM39A,GMFB,SREK1,LRRC1,CYFIP2,GOSR1,CYB5A,KIF2A,PDCD6,ORMDL2,DTX4,PML,MBOAT1,CD81,PTDSS1,ALS2 |
| 2.585e-02 | -3.66 | GSE8621_UNSTIM_VS_LPS_PRIMED_UNSTIM_MACROPHAGE_DN | MSigDB lists | GSE8621_UNSTIM_VS_LPS_PRIMED_UNSTIM_MACROPHAGE_DN | 184 | 38 | 17377 | 2626 |
WSB2,RHOG,TBC1D12,GPR132,CKLF,LUZP1,GXYLT1,MDH2,UQCR10,MRPS26,YTHDF3,USP39,CDK11B,BECN1,PRKACA,GLRX3,ARL6IP6,LIN9,MLX,RABGAP1L,PPP1R12C,DDX31,PRKDC,SCFD2,SLC26A6,KCTD20,NFATC2,NDUFA7,HERPUD2,KDM1B,GOSR1,FADD,SOCS7,OSBPL11,PLAA,ZNF367,HIPK2,DBI |
| 2.585e-02 | -3.66 | GSE10325_CD4_TCELL_VS_LUPUS_CD4_TCELL_DN | MSigDB lists | GSE10325_CD4_TCELL_VS_LUPUS_CD4_TCELL_DN | 184 | 38 | 17377 | 2626 |
WSB2,PARP12,MRPL42,PTTG1,CDCA3,TAP1,UBE2Q1,MYL6B,RGS1,FBXO22,CREM,PTPN2,CAPN2,IRF4,CLUAP1,PSMA6,SP100,ZCCHC2,CAPZA1,CDC5L,PPIF,TRAFD1,KLF10,LAP3,PSMB9,SLC50A1,ISG15,FAS,HLA-B,KIF18B,TFDP1,PRPS2,PIAS2,STAT1,SNRPG,LRP8,IFI16,PFKP |
| 2.585e-02 | -3.66 | GSE26030_TH1_VS_TH17_DAY15_POST_POLARIZATION_DN | MSigDB lists | GSE26030_TH1_VS_TH17_DAY15_POST_POLARIZATION_DN | 184 | 38 | 17377 | 2626 |
ZBED3,PPIB,AGRN,RACGAP1,APP,SUB1,DPYSL2,RABGAP1L,RCSD1,SOCS6,FAM89B,TIMELESS,ANXA5,NDUFS8,TAGLN2,CITED2,PLCL2,PABPC1,S100A6,LDHB,ANKLE2,SEC61B,EMB,PPP1R21,MKI67,VDAC2,PLEC,OGFR,RPS9,SERP1,RPSA,ARHGAP15,MAN2A2,OSBPL11,PRDX5,COX8A,GPI,MZT2B |
| 2.585e-02 | -3.66 | GSE3039_CD4_TCELL_VS_B2_BCELL_DN | MSigDB lists | GSE3039_CD4_TCELL_VS_B2_BCELL_DN | 184 | 38 | 17377 | 2626 |
HNRNPAB,SUCLG1,GORASP1,UQCR10,KCTD17,SDF2L1,POMP,PLXNA1,RRN3,SNUPN,ATIC,MRPS27,FNIP2,NDUFS8,RPL19,PPA1,PABPC1,TMBIM1,SOCS5,METTL1,ACP2,SIGMAR1,WDR18,WDR81,MTX1,ODC1,SERP1,USP36,AKAP1,SLC19A1,AEN,SPRYD4,RPS26,SLC25A39,ZMAT3,GCSH,DDB1,CCDC137 |
| 2.588e-02 | -3.65 | G_TR_1 | prosite domains | PS00301 | 9 | 4 | 12060 | 1670 |
GUF1,GFM2,GSPT2,TUFM |
| 2.588e-02 | -3.65 | VHS | prosite domains | PS50179 | 9 | 4 | 12060 | 1670 |
HGS,GGA2,GGA1,STAM |
| 2.589e-02 | -3.65 | PNMA1 (PNMA family member 1) | protein interactions | 9240 | 130 | 30 | 17029 | 2761 |
COX5B,UBQLN4,TSPYL4,WDYHV1,SNRPB,VAV2,ARID5A,PCGF6,C5orf30,PSMA1,CHIC2,CHMP2B,REPS1,BTBD1,MOAP1,MED8,SUV39H2,FAM110A,PIN1,ACOX1,UBA5,TTC9C,YWHAZ,ACTB,MRPL11,SPATC1L,CNNM3,PARD3,BYSL,ZNF564 |
| 2.590e-02 | -3.65 | intra-Golgi vesicle-mediated transport | biological process | GO:0006891 | 34 | 10 | 17256 | 2622 |
NAPG,COPA,NSF,COPE,VTI1A,COG1,RAB6A,GOSR1,COPG2,COPB2 |
| 2.590e-02 | -3.65 | positive regulation of telomere maintenance via telomerase | biological process | GO:0032212 | 34 | 10 | 17256 | 2622 |
MAP3K4,CCT2,NEK7,AURKB,MAPK1,PARN,POT1,CCT8,XRCC5,MAPK3 |
| 2.590e-02 | -3.65 | 7-methylguanosine RNA capping | biological process | GO:0009452 | 34 | 10 | 17256 | 2622 |
POLR2I,POLR2J,POLR2G,POLR2L,POLR2K,CMTR2,POLR2D,GTF2H2,POLR2A,GTF2F1 |
| 2.590e-02 | -3.65 | RNA capping | biological process | GO:0036260 | 34 | 10 | 17256 | 2622 |
POLR2I,POLR2J,POLR2G,POLR2L,POLR2K,CMTR2,POLR2D,GTF2H2,POLR2A,GTF2F1 |
| 2.591e-02 | -3.65 | V$CHOP_01 | MSigDB lists | V$CHOP_01 | 224 | 45 | 17377 | 2626 |
ZBTB10,IMMT,GGNBP2,PLXNC1,TRERF1,ZBTB37,CAST,FAM129A,GLUD1,SLC4A2,STMN1,WWP2,ANKRD28,MOAP1,CDK5,TFAP4,RNF121,IARS,ATG3,DPYSL2,TNPO3,PCYT2,RNF19A,SOCS5,MOSPD1,SRPK2,KDM3B,EXOSC6,WIPF1,RAB3IP,SOX4,PHF6,RAD54B,SUPT16H,HMGN2,ADSS,HHEX,AHNAK,SYNCRIP,MAP4,SH3GLB2,HMGB2,ZBTB11,TOB1,ATXN7L2 |
| 2.594e-02 | -3.65 | RNA polymerase II activating transcription factor binding | molecular function | GO:0001102 | 48 | 13 | 17224 | 2647 |
RB1,RBL1,SETD3,HIPK2,LDB1,MEF2A,MEF2D,TAF12,TAF6L,CREB1,ATF2,TAF6,MAD2L2 |
| 2.594e-02 | -3.65 | Degradation of beta-catenin by the destruction complex | REACTOME pathways | R-HSA-195253 | 83 | 21 | 10287 | 1696 |
PSMA8,RBX1,PSMB7,PSMA1,CUL1,FRAT2,CSNK1A1,PSMB9,PSMD9,PSMB3,PSMC4,PPP2CA,PSMD2,PSMA6,PSMD1,PPP2R5A,RPS27A,PSMD8,AXIN1,PSMD3,PSMC1 |
| 2.598e-02 | -3.65 | Mismatch Repair | REACTOME pathways | R-HSA-5358508 | 15 | 6 | 10287 | 1696 |
RPA2,PCNA,MSH6,RPA1,PMS2,MSH2 |
| 2.598e-02 | -3.65 | Processive synthesis on the lagging strand | REACTOME pathways | R-HSA-69183 | 15 | 6 | 10287 | 1696 |
POLA2,RPA2,PCNA,PRIM2,RPA1,PRIM1 |
| 2.600e-02 | -3.65 | - | gene3d domains | 3.30.800.10 | 8 | 4 | 8148 | 1295 |
PIKFYVE,PIP4K2A,PIP5K1C,PIP4K2C |
| 2.601e-02 | -3.65 | skin-lower_leg-malignant_melanoma-superficial_spreading | COSMIC cancer mutations | skin-lower_leg-malignant_melanoma-superficial_spreading | 5 | 3 | 17385 | 2587 |
KRAS,NRAS,HRAS |
| 2.601e-02 | -3.65 | endometrium-hyperplasia-complex-atypical | COSMIC cancer mutations | endometrium-hyperplasia-complex-atypical | 5 | 3 | 17385 | 2587 |
KRAS,PTEN,CDKN2A |
| 2.601e-02 | -3.65 | kidney-other-angiomyolipoma | COSMIC cancer mutations | kidney-other-angiomyolipoma | 5 | 3 | 17385 | 2587 |
TSC1,TSC2,VHL |
| 2.601e-02 | -3.65 | mixed_papillary_and_follicular_carcinoma | COSMIC cancer mutations | mixed_papillary_and_follicular_carcinoma | 5 | 3 | 17385 | 2587 |
KRAS,NRAS,HRAS |
| 2.601e-02 | -3.65 | haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-monoclonal_gammopathy_of_undetermined_significance | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-monoclonal_gammopathy_of_undetermined_significance | 5 | 3 | 17385 | 2587 |
FGFR3,KRAS,NRAS |
| 2.601e-02 | -3.65 | intraepithelial_neoplasia | COSMIC cancer mutations | intraepithelial_neoplasia | 5 | 3 | 17385 | 2587 |
GNAS,KRAS,CDKN2A |
| 2.601e-02 | -3.65 | cemento-ossifying_fibroma | COSMIC cancer mutations | cemento-ossifying_fibroma | 5 | 3 | 17385 | 2587 |
GNAS,FUS,CDC73 |
| 2.601e-02 | -3.65 | lung-carcinoma-lymphoepithelioma_like_carcinoma | COSMIC cancer mutations | lung-carcinoma-lymphoepithelioma_like_carcinoma | 5 | 3 | 17385 | 2587 |
KIF5B,KRAS,EML4 |
| 2.601e-02 | -3.65 | acute_lymphoblastic_leukaemia_therapy_related | COSMIC cancer mutations | acute_lymphoblastic_leukaemia_therapy_related | 5 | 3 | 17385 | 2587 |
KRAS,NRAS,HRAS |
| 2.601e-02 | -3.65 | large_cell_neuroendocrine_carcinoma | COSMIC cancer mutations | large_cell_neuroendocrine_carcinoma | 5 | 3 | 17385 | 2587 |
RB1,KRAS,CDKN2A |
| 2.601e-02 | -3.65 | salivary_gland-lymph_node-carcinoma-adenoid_cystic_carcinoma | COSMIC cancer mutations | salivary_gland-lymph_node-carcinoma-adenoid_cystic_carcinoma | 5 | 3 | 17385 | 2587 |
KRAS,NRAS,HRAS |
| 2.601e-02 | -3.65 | salivary_gland-sphenoid_sinus-carcinoma-adenoid_cystic_carcinoma | COSMIC cancer mutations | salivary_gland-sphenoid_sinus-carcinoma-adenoid_cystic_carcinoma | 5 | 3 | 17385 | 2587 |
KRAS,NRAS,HRAS |
| 2.601e-02 | -3.65 | urinary_tract-bladder-carcinoma-undifferentiated_carcinoma | COSMIC cancer mutations | urinary_tract-bladder-carcinoma-undifferentiated_carcinoma | 5 | 3 | 17385 | 2587 |
KRAS,NRAS,HRAS |
| 2.601e-02 | -3.65 | plasmacytoma | COSMIC cancer mutations | plasmacytoma | 5 | 3 | 17385 | 2587 |
KRAS,NRAS,VHL |
| 2.601e-02 | -3.65 | vagina-carcinoma-adenoid_cystic_carcinoma | COSMIC cancer mutations | vagina-carcinoma-adenoid_cystic_carcinoma | 5 | 3 | 17385 | 2587 |
KRAS,NRAS,HRAS |
| 2.601e-02 | -3.65 | haematopoietic_and_lymphoid_tissue-extranodal-lymphoid_neoplasm-marginal_zone_lymphoma | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-extranodal-lymphoid_neoplasm-marginal_zone_lymphoma | 5 | 3 | 17385 | 2587 |
BIRC3,SF3B1,CDKN2A |
| 2.601e-02 | -3.65 | salivary_gland-tongue-carcinoma-cribriform_adenocarcinoma | COSMIC cancer mutations | salivary_gland-tongue-carcinoma-cribriform_adenocarcinoma | 5 | 3 | 17385 | 2587 |
KRAS,NRAS,HRAS |
| 2.601e-02 | -3.65 | sublingual | COSMIC cancer mutations | sublingual | 5 | 3 | 17385 | 2587 |
KRAS,NRAS,HRAS |
| 2.601e-02 | -3.65 | ear_canal | COSMIC cancer mutations | ear_canal | 5 | 3 | 17385 | 2587 |
KRAS,NRAS,HRAS |
| 2.601e-02 | -3.65 | buccal | COSMIC cancer mutations | buccal | 5 | 3 | 17385 | 2587 |
KRAS,NRAS,HRAS |
| 2.601e-02 | -3.65 | bone-femur-other-giant_cell_tumour | COSMIC cancer mutations | bone-femur-other-giant_cell_tumour | 5 | 3 | 17385 | 2587 |
EWSR1,H3F3A,HRAS |
| 2.601e-02 | -3.65 | haematopoietic_and_lymphoid_tissue-thyroid-lymphoid_neoplasm-diffuse_large_B_cell_lymphoma | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-thyroid-lymphoid_neoplasm-diffuse_large_B_cell_lymphoma | 5 | 3 | 17385 | 2587 |
KRAS,NRAS,HRAS |
| 2.601e-02 | -3.65 | lung-bronchus-carcinoma-adenoid_cystic_carcinoma | COSMIC cancer mutations | lung-bronchus-carcinoma-adenoid_cystic_carcinoma | 5 | 3 | 17385 | 2587 |
KRAS,NRAS,HRAS |
| 2.601e-02 | -3.65 | skin-hip-other-seborrhoeic_keratosis | COSMIC cancer mutations | skin-hip-other-seborrhoeic_keratosis | 5 | 3 | 17385 | 2587 |
FGFR3,HRAS,PTPN11 |
| 2.601e-02 | -3.65 | complex-atypical | COSMIC cancer mutations | complex-atypical | 5 | 3 | 17385 | 2587 |
KRAS,PTEN,CDKN2A |
| 2.601e-02 | -3.65 | thyroid-other-Graves_disease | COSMIC cancer mutations | thyroid-other-Graves_disease | 5 | 3 | 17385 | 2587 |
GNAS,NRAS,CCDC6 |
| 2.601e-02 | -3.65 | skin-ear-malignant_melanoma-spitzoid | COSMIC cancer mutations | skin-ear-malignant_melanoma-spitzoid | 5 | 3 | 17385 | 2587 |
NRAS,HRAS,CDKN2A |
| 2.601e-02 | -3.65 | angiomyolipoma | COSMIC cancer mutations | angiomyolipoma | 5 | 3 | 17385 | 2587 |
TSC1,TSC2,VHL |
| 2.601e-02 | -3.65 | skin-back-other-atypical_Spitzoid_tumour | COSMIC cancer mutations | skin-back-other-atypical_Spitzoid_tumour | 5 | 3 | 17385 | 2587 |
NRAS,HRAS,CDKN2A |
| 2.601e-02 | -3.65 | cervix-in_situ_neoplasm-cervical_intraepithelial_neoplasia_Grade_II | COSMIC cancer mutations | cervix-in_situ_neoplasm-cervical_intraepithelial_neoplasia_Grade_II | 5 | 3 | 17385 | 2587 |
NRAS,HRAS,CDKN2A |
| 2.601e-02 | -3.65 | salivary_gland-buccal-carcinoma-adenoid_cystic_carcinoma | COSMIC cancer mutations | salivary_gland-buccal-carcinoma-adenoid_cystic_carcinoma | 5 | 3 | 17385 | 2587 |
KRAS,NRAS,HRAS |
| 2.601e-02 | -3.65 | haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-acute_lymphoblastic_leukaemia_therapy_related | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-acute_lymphoblastic_leukaemia_therapy_related | 5 | 3 | 17385 | 2587 |
KRAS,NRAS,HRAS |
| 2.601e-02 | -3.65 | skin-forearm-other-seborrhoeic_keratosis | COSMIC cancer mutations | skin-forearm-other-seborrhoeic_keratosis | 5 | 3 | 17385 | 2587 |
FGFR3,HRAS,PTPN11 |
| 2.601e-02 | -3.65 | tectum | COSMIC cancer mutations | tectum | 5 | 3 | 17385 | 2587 |
H3F3A,PTEN,CDKN2A |
| 2.601e-02 | -3.65 | cervical_intraepithelial_neoplasia_Grade_II | COSMIC cancer mutations | cervical_intraepithelial_neoplasia_Grade_II | 5 | 3 | 17385 | 2587 |
NRAS,HRAS,CDKN2A |
| 2.601e-02 | -3.65 | sphenoid_sinus | COSMIC cancer mutations | sphenoid_sinus | 5 | 3 | 17385 | 2587 |
KRAS,NRAS,HRAS |
| 2.601e-02 | -3.65 | haematopoietic_and_lymphoid_tissue-thyroid-lymphoid_neoplasm-follicular_lymphoma | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-thyroid-lymphoid_neoplasm-follicular_lymphoma | 5 | 3 | 17385 | 2587 |
KRAS,NRAS,HRAS |
| 2.601e-02 | -3.65 | biliary_tract-gallbladder-carcinoma-undifferentiated_carcinoma | COSMIC cancer mutations | biliary_tract-gallbladder-carcinoma-undifferentiated_carcinoma | 5 | 3 | 17385 | 2587 |
KRAS,NRAS,SF3B1 |
| 2.601e-02 | -3.65 | stomach-other-dysplasia | COSMIC cancer mutations | stomach-other-dysplasia | 5 | 3 | 17385 | 2587 |
GNAS,KRAS,HRAS |
| 2.601e-02 | -3.65 | salivary_gland-mouth_floor-carcinoma-cribriform_adenocarcinoma | COSMIC cancer mutations | salivary_gland-mouth_floor-carcinoma-cribriform_adenocarcinoma | 5 | 3 | 17385 | 2587 |
KRAS,NRAS,HRAS |
| 2.601e-02 | -3.65 | salivary_gland-ear_canal-carcinoma-adenoid_cystic_carcinoma | COSMIC cancer mutations | salivary_gland-ear_canal-carcinoma-adenoid_cystic_carcinoma | 5 | 3 | 17385 | 2587 |
KRAS,NRAS,HRAS |
| 2.601e-02 | -3.65 | thyroid-carcinoma-mixed_papillary_and_follicular_carcinoma | COSMIC cancer mutations | thyroid-carcinoma-mixed_papillary_and_follicular_carcinoma | 5 | 3 | 17385 | 2587 |
KRAS,NRAS,HRAS |
| 2.601e-02 | -3.65 | monoclonal_gammopathy_of_undetermined_significance | COSMIC cancer mutations | monoclonal_gammopathy_of_undetermined_significance | 5 | 3 | 17385 | 2587 |
FGFR3,KRAS,NRAS |
| 2.601e-02 | -3.65 | cribriform_adenocarcinoma | COSMIC cancer mutations | cribriform_adenocarcinoma | 5 | 3 | 17385 | 2587 |
KRAS,NRAS,HRAS |
| 2.601e-02 | -3.65 | Graves_disease | COSMIC cancer mutations | Graves_disease | 5 | 3 | 17385 | 2587 |
GNAS,NRAS,CCDC6 |
| 2.602e-02 | -3.65 | NA-bd_OB-fold | interpro domains | IPR012340 | 75 | 18 | 18492 | 2768 |
EIF5A,KARS,POLR2G,RPL8,DHX8,MCM2,RPA1,RPA2,CSDE1,MRPL2,MCM5,EXOSC1,NABP1,NABP2,YBX1,PDCD11,POT1,CCAR1 |
| 2.607e-02 | -3.65 | Thyroid hormone signaling pathway | KEGG pathways | hsa04919 | 116 | 27 | 7161 | 1149 |
PDPK1,NRAS,KAT2A,TSC2,AKT2,RAF1,SLC2A1,MED13L,KRAS,NOTCH2,PRKACA,MAP2K2,RHEB,MAPK3,RXRB,ATP1A1,MDM2,ATP2A2,PIK3R2,STAT1,ACTB,NCOA1,MAPK1,HRAS,NCOA2,HDAC2,PFKP |
| 2.612e-02 | -3.64 | KEGG_PYRUVATE_METABOLISM | MSigDB lists | KEGG_PYRUVATE_METABOLISM | 39 | 11 | 17377 | 2626 |
ACYP1,MDH2,HAGHL,LDHA,AKR1B1,ACAT1,GLO1,MDH1,HAGH,ALDH9A1,LDHB |
| 2.612e-02 | -3.64 | PID_RET_PATHWAY | MSigDB lists | PID_RET_PATHWAY | 39 | 11 | 17377 | 2626 |
RAP1A,RHOA,SHC1,NCK1,RAC1,PTPN11,CREB1,MAPK1,PRKACA,HRAS,MAPK3 |
| 2.612e-02 | -3.64 | STEIN_ESRRA_TARGETS_RESPONSIVE_TO_ESTROGEN_DN | MSigDB lists | STEIN_ESRRA_TARGETS_RESPONSIVE_TO_ESTROGEN_DN | 39 | 11 | 17377 | 2626 |
DTL,PCNA,MCM10,ATAD2,CELSR2,MCM5,RRM1,WDHD1,CDC6,MCM2,SMC4 |
| 2.612e-02 | -3.64 | GO_BASE_EXCISION_REPAIR | MSigDB lists | GO_BASE_EXCISION_REPAIR | 39 | 11 | 17377 | 2626 |
RPA2,POLE,HUWE1,NEIL3,XPA,MPG,OGG1,NEIL2,MBD4,POLQ,RPA1 |
| 2.612e-02 | -3.64 | RIZ_ERYTHROID_DIFFERENTIATION_CCNE1 | MSigDB lists | RIZ_ERYTHROID_DIFFERENTIATION_CCNE1 | 39 | 11 | 17377 | 2626 |
SP3,TCF12,POLR2J,RAB7A,TFDP1,E2F1,DHX9,PIAS2,HMGB2,AURKB,MBD4 |
| 2.612e-02 | -3.64 | REACTOME_RNA_POL_II_TRANSCRIPTION_PRE_INITIATION_AND_PROMOTER_OPENING | MSigDB lists | REACTOME_RNA_POL_II_TRANSCRIPTION_PRE_INITIATION_AND_PROMOTER_OPENING | 39 | 11 | 17377 | 2626 |
POLR2I,POLR2G,POLR2L,POLR2J,POLR2K,POLR2D,TAF12,GTF2H2,TAF6,POLR2A,GTF2F1 |
| 2.612e-02 | -3.64 | GENTILE_UV_RESPONSE_CLUSTER_D8 | MSigDB lists | GENTILE_UV_RESPONSE_CLUSTER_D8 | 39 | 11 | 17377 | 2626 |
PPP1R12A,TAB2,STK38,HNRNPH3,RBMS1,YY1,NR2F2,MAPK14,TSPAN5,RBM15B,CBX3 |
| 2.614e-02 | -3.64 | Transcriptional activation of mitochondrial biogenesis | REACTOME pathways | R-HSA-2151201 | 45 | 13 | 10287 | 1696 |
NRF1,MTERF1,GABPA,TWNK,CYCS,NCOA1,MEF2D,ATP5F1B,CREB1,POLG2,ATF2,NCOA2,CARM1 |
| 2.616e-02 | -3.64 | RAMASWAMY_METASTASIS_UP | MSigDB lists | RAMASWAMY_METASTASIS_UP | 64 | 16 | 17377 | 2626 |
HNRNPAB,RBM42,UBN1,DHPS,VAV2,PTTG1,TMEM147,CAND1,EIF3K,BIRC5,COX7A2L,AKAP8,UPF2,NUP62,GPI,VPS13B |
| 2.616e-02 | -3.64 | GO_PROTEIN_POLYMERIZATION | MSigDB lists | GO_PROTEIN_POLYMERIZATION | 64 | 16 | 17377 | 2626 |
ZNF207,CHMP2A,CORO7,RAC1,TUBGCP5,TUBGCP2,FBXO5,MID1IP1,WAS,CHMP4A,GOLGA2,CENPJ,NDE1,TTC17,UBE2C,CSNK1D |
| 2.622e-02 | -3.64 | Porin_3 | pfam domains | PF01459 | 5 | 3 | 17054 | 2545 |
VDAC1,TOMM40,VDAC2 |
| 2.622e-02 | -3.64 | CobW_C | pfam domains | PF07683 | 5 | 3 | 17054 | 2545 |
CBWD1,CBWD2,CBWD5 |
| 2.622e-02 | -3.64 | ATP-synt_C | pfam domains | PF00137 | 5 | 3 | 17054 | 2545 |
ATP6V0B,ATP6V0C,ATP5MC3 |
| 2.622e-02 | -3.64 | NAC | pfam domains | PF01849 | 5 | 3 | 17054 | 2545 |
BTF3,NACA,BTF3L4 |
| 2.622e-02 | -3.64 | cobW | pfam domains | PF02492 | 5 | 3 | 17054 | 2545 |
CBWD1,CBWD2,CBWD5 |
| 2.622e-02 | -3.64 | DZF | pfam domains | PF07528 | 5 | 3 | 17054 | 2545 |
STRBP,ZFR,ILF3 |
| 2.622e-02 | -3.64 | ATP-synt_ab | pfam domains | PF00006 | 5 | 3 | 17054 | 2545 |
ATP5F1A,ATP5F1B,ATP6V1B2 |
| 2.622e-02 | -3.64 | YTH | pfam domains | PF04146 | 5 | 3 | 17054 | 2545 |
YTHDC1,YTHDF3,YTHDC2 |
| 2.622e-02 | -3.64 | ATP-synt_ab_N | pfam domains | PF02874 | 5 | 3 | 17054 | 2545 |
ATP5F1A,ATP5F1B,ATP6V1B2 |
| 2.622e-02 | -3.64 | GSE10422_WT_VS_BAFF_TRANSGENIC_LN_BCELL_UP | MSigDB lists | GSE10422_WT_VS_BAFF_TRANSGENIC_LN_BCELL_UP | 156 | 33 | 17377 | 2626 |
OTUD5,ZDHHC8,STRN4,PMS2,MOGS,CCNL2,UBE4A,REEP5,POFUT1,DPYSL2,FUT8,ZRANB1,SLC39A9,PDPK1,SEPT9,ETV3,DCAF8,HELB,LRRC8A,DAPK3,SH3BP5,MTMR3,DTWD1,DNAJC10,UPF1,OSBPL11,JAK1,MAPK6,WDR76,CD81,ACSF2,NAA60,CAPN1 |
| 2.623e-02 | -3.64 | poly(A) binding | molecular function | GO:0008143 | 16 | 6 | 17224 | 2647 |
TIA1,SYNCRIP,EIF4A3,PABPC1,PPIE,PABPC4 |
| 2.624e-02 | -3.64 | cysteine-type peptidase activity | molecular function | GO:0008234 | 198 | 41 | 17224 | 2647 |
USP7,OTUD5,CYLD,ATXN3,CASP6,USP39,USP48,WDR48,USP5,CFLAR,ATG4A,CAPN2,CTSS,UCHL5,TANK,SRI,JOSD1,ZRANB1,SENP1,USP34,TNFAIP3,KAT2A,USP42,USP10,USP22,OTUD3,PEF1,USP21,USP36,CTSL,ANKZF1,PDCD6,CAPN7,USP32,USP20,VCPIP1,USP11,USP53,ESPL1,CAPN1,USP13 |
| 2.626e-02 | -3.64 | Lysosome Vesicle Biogenesis | REACTOME pathways | R-HSA-432720 | 36 | 11 | 10287 | 1696 |
GNS,CHMP2A,HGS,AP1M1,DNM2,AP1S1,ARF1,AP1B1,CLTB,AP4E1,APP |
| 2.628e-02 | -3.64 | ZCCHC13 (zinc finger CCHC-type containing 13) | protein interactions | 389874 | 2 | 2 | 17029 | 2761 |
ATXN1,SIAH1 |
| 2.628e-02 | -3.64 | LMNTD1 (lamin tail domain containing 1) | protein interactions | 160492 | 2 | 2 | 17029 | 2761 |
BRCA1,APP |
| 2.628e-02 | -3.64 | MAGEA9 (MAGE family member A9) | protein interactions | 4108 | 2 | 2 | 17029 | 2761 |
APPL1,EGLN1 |
| 2.628e-02 | -3.64 | BEND2 (BEN domain containing 2) | protein interactions | 139105 | 2 | 2 | 17029 | 2761 |
ATXN1,APP |
| 2.628e-02 | -3.64 | BcRF1 (protein UL87;) | protein interactions | 3783690 | 2 | 2 | 17029 | 2761 |
POLR2I,POLR2A |
| 2.628e-02 | -3.64 | esc (extra sexcombs) | protein interactions | 34595 | 2 | 2 | 17029 | 2761 |
CSNK2A1,EZH1 |
| 2.628e-02 | -3.64 | Apbb2 (amyloid beta (A4) precursor protein-binding, family B, member 2) | protein interactions | 11787 | 2 | 2 | 17029 | 2761 |
SMURF1,SMAD4 |
| 2.628e-02 | -3.64 | ZNF28 (zinc finger protein 28) | protein interactions | 7576 | 2 | 2 | 17029 | 2761 |
TRIM28,MAPK6 |
| 2.628e-02 | -3.64 | ERCC6L2 (ERCC excision repair 6 like 2) | protein interactions | 375748 | 2 | 2 | 17029 | 2761 |
CYREN,NEK6 |
| 2.628e-02 | -3.64 | Cdc40 (cell division cycle 40) | protein interactions | 71713 | 2 | 2 | 17029 | 2761 |
SMAD2,SMURF1 |
| 2.628e-02 | -3.64 | SHCBP1L (SHC binding and spindle associated 1 like) | protein interactions | 81626 | 2 | 2 | 17029 | 2761 |
BRAP,KRAS |
| 2.628e-02 | -3.64 | HSPA4 (heat shock protein family A (Hsp70) member 4) | protein interactions | 100338049 | 2 | 2 | 17029 | 2761 |
SEC61B,SERP1 |
| 2.628e-02 | -3.64 | TOM20 (Tom20p) | protein interactions | 852973 | 2 | 2 | 17029 | 2761 |
CSNK2A1,CSNK1A1 |
| 2.628e-02 | -3.64 | ENGASE (endo-beta-N-acetylglucosaminidase) | protein interactions | 64772 | 2 | 2 | 17029 | 2761 |
GNS,ZP3 |
| 2.628e-02 | -3.64 | Tsc2 (tuberous sclerosis 2) | protein interactions | 22084 | 2 | 2 | 17029 | 2761 |
TSC1,SRSF5 |
| 2.628e-02 | -3.64 | GPER1 (G protein-coupled estrogen receptor 1) | protein interactions | 2852 | 2 | 2 | 17029 | 2761 |
PTEN,PTTG1 |
| 2.628e-02 | -3.64 | RPL13AP17 (ribosomal protein L13a pseudogene 17) | protein interactions | 399670 | 2 | 2 | 17029 | 2761 |
SYNCRIP,GOPC |
| 2.628e-02 | -3.64 | IGHE (immunoglobulin heavy constant epsilon) | protein interactions | 3497 | 2 | 2 | 17029 | 2761 |
SART1,STAT6 |
| 2.628e-02 | -3.64 | ZNF584 (zinc finger protein 584) | protein interactions | 201514 | 2 | 2 | 17029 | 2761 |
KRAS,LZTR1 |
| 2.628e-02 | -3.64 | MRPL39 (mitochondrial 54S ribosomal protein YmL39) | protein interactions | 855002 | 2 | 2 | 17029 | 2761 |
TARDBP,BRCA1 |
| 2.628e-02 | -3.64 | CYLC2 (cylicin 2) | protein interactions | 1539 | 2 | 2 | 17029 | 2761 |
POT1,TERF2 |
| 2.628e-02 | -3.64 | fzr1.L (fizzy/cell division cycle 20 related 1 L homeolog) | protein interactions | 380351 | 2 | 2 | 17029 | 2761 |
CCNB1,UBE2C |
| 2.628e-02 | -3.64 | Tubb2b (tubulin, beta 2B class IIb) | protein interactions | 291081 | 2 | 2 | 17029 | 2761 |
ATXN3,DYNLL1 |
| 2.628e-02 | -3.64 | CEP112 (centrosomal protein 112) | protein interactions | 201134 | 2 | 2 | 17029 | 2761 |
USP7,FUS |
| 2.628e-02 | -3.64 | CCNB3 (cyclin B3) | protein interactions | 85417 | 2 | 2 | 17029 | 2761 |
CDK2,APP |
| 2.628e-02 | -3.64 | Ambra1 (autophagy/beclin 1 regulator 1) | protein interactions | 228361 | 2 | 2 | 17029 | 2761 |
SPRYD4,DDA1 |
| 2.628e-02 | -3.64 | NUDT7 (nudix hydrolase 7) | protein interactions | 283927 | 2 | 2 | 17029 | 2761 |
CUL1,PEX5 |
| 2.628e-02 | -3.64 | Cdkn1a (cyclin-dependent kinase inhibitor 1A (P21)) | protein interactions | 12575 | 2 | 2 | 17029 | 2761 |
PCNA,DDB1 |
| 2.628e-02 | -3.64 | ORF67 (capsid docking protein on nuclear lamina) | protein interactions | 4961524 | 2 | 2 | 17029 | 2761 |
PDE3B,DYNC1LI2 |
| 2.628e-02 | -3.64 | LOC389842 (RAN binding protein 1 pseudogene) | protein interactions | 389842 | 2 | 2 | 17029 | 2761 |
EWSR1,HUWE1 |
| 2.628e-02 | -3.64 | IAH1 (isoamyl acetate hydrolyzing esterase 1 (putative)) | protein interactions | 285148 | 2 | 2 | 17029 | 2761 |
MCM2,UCK2 |
| 2.628e-02 | -3.64 | TDRD6 (tudor domain containing 6) | protein interactions | 221400 | 2 | 2 | 17029 | 2761 |
TERF1,TERF2 |
| 2.628e-02 | -3.64 | NXPE4 (neurexophilin and PC-esterase domain family member 4) | protein interactions | 54827 | 2 | 2 | 17029 | 2761 |
PRKACA,SRPK2 |
| 2.628e-02 | -3.64 | C6orf48 (chromosome 6 open reading frame 48) | protein interactions | 50854 | 2 | 2 | 17029 | 2761 |
KRAS,AGO2 |
| 2.628e-02 | -3.64 | skp2.L (S-phase kinase-associated protein 2, E3 ubiquitin protein ligase L homeolog) | protein interactions | 734901 | 2 | 2 | 17029 | 2761 |
CUL1,RBX1 |
| 2.628e-02 | -3.64 | YAF9 (Yaf9p) | protein interactions | 855616 | 2 | 2 | 17029 | 2761 |
BRCA1,H3F3A |
| 2.628e-02 | -3.64 | BAG6 (BCL2 associated athanogene 6) | protein interactions | 100350337 | 2 | 2 | 17029 | 2761 |
SEC61B,SERP1 |
| 2.628e-02 | -3.64 | SNURF (SNRPN upstream reading frame) | protein interactions | 8926 | 2 | 2 | 17029 | 2761 |
APP,SRPK2 |
| 2.628e-02 | -3.64 | Irak2 (interleukin-1 receptor-associated kinase 2) | protein interactions | 108960 | 2 | 2 | 17029 | 2761 |
SMAD2,SMURF1 |
| 2.628e-02 | -3.64 | PPP1CA (protein phosphatase 1 catalytic subunit alpha) | protein interactions | 516175 | 2 | 2 | 17029 | 2761 |
RB1,RBL1 |
| 2.628e-02 | -3.64 | UBC9 (E2 SUMO-conjugating protein UBC9) | protein interactions | 851495 | 2 | 2 | 17029 | 2761 |
PCNA,UBE2I |
| 2.628e-02 | -3.64 | Ncl (nucleolin) | protein interactions | 17975 | 2 | 2 | 17029 | 2761 |
PTEN,TCF3 |
| 2.628e-02 | -3.64 | ZNF720 (zinc finger protein 720) | protein interactions | 124411 | 2 | 2 | 17029 | 2761 |
APP,TRIM28 |
| 2.628e-02 | -3.64 | DKFZP434K028 (uncharacterized LOC26070) | protein interactions | 26070 | 2 | 2 | 17029 | 2761 |
LYN,APP |
| 2.628e-02 | -3.64 | ZNF701 (zinc finger protein 701) | protein interactions | 55762 | 2 | 2 | 17029 | 2761 |
TRIM28,GPATCH4 |
| 2.628e-02 | -3.64 | TCTA (T cell leukemia translocation altered) | protein interactions | 6988 | 2 | 2 | 17029 | 2761 |
ATXN1,SMAD4 |
| 2.628e-02 | -3.64 | Appl1 (adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1) | protein interactions | 72993 | 2 | 2 | 17029 | 2761 |
RHEB,RHEBL1 |
| 2.628e-02 | -3.64 | NEXMIF (neurite extension and migration factor) | protein interactions | 340533 | 2 | 2 | 17029 | 2761 |
TERF1,TERF2 |
| 2.628e-02 | -3.64 | BEST1 (bestrophin 1) | protein interactions | 7439 | 2 | 2 | 17029 | 2761 |
PPP2CA,PPP2R5A |
| 2.628e-02 | -3.64 | RPS15AP25 (ribosomal protein S15a pseudogene 25) | protein interactions | 728774 | 2 | 2 | 17029 | 2761 |
CUL1,CAND1 |
| 2.628e-02 | -3.64 | SYCP1 (synaptonemal complex protein 1) | protein interactions | 6847 | 2 | 2 | 17029 | 2761 |
CREB1,MCM2 |
| 2.628e-02 | -3.64 | Aldh4a1 (aldehyde dehydrogenase 4 family, member A1) | protein interactions | 212647 | 2 | 2 | 17029 | 2761 |
SMAD2,RAF1 |
| 2.628e-02 | -3.64 | ART4 (ADP-ribosyltransferase 4 (Dombrock blood group)) | protein interactions | 420 | 2 | 2 | 17029 | 2761 |
UPF2,APP |
| 2.628e-02 | -3.64 | HIST2H2BA (histone cluster 2 H2B family member a (pseudogene)) | protein interactions | 337875 | 2 | 2 | 17029 | 2761 |
MEN1,NOC2L |
| 2.628e-02 | -3.64 | CCDC149 (coiled-coil domain containing 149) | protein interactions | 91050 | 2 | 2 | 17029 | 2761 |
APP,PRNP |
| 2.628e-02 | -3.64 | SLC16A8 (solute carrier family 16 member 8) | protein interactions | 23539 | 2 | 2 | 17029 | 2761 |
RAB1A,DNAJB9 |
| 2.628e-02 | -3.64 | FLJ20712 (uncharacterized FLJ20712) | protein interactions | 55025 | 2 | 2 | 17029 | 2761 |
PLK1,E2F4 |
| 2.628e-02 | -3.64 | DBR1 (RNA lariat debranching enzyme) | protein interactions | 853708 | 2 | 2 | 17029 | 2761 |
TARDBP,FUS |
| 2.628e-02 | -3.64 | ORF56 (primase subunit of helicase-primase complex) | protein interactions | 4961445 | 2 | 2 | 17029 | 2761 |
TOMM40,PRKACA |
| 2.628e-02 | -3.64 | Mbd3 (methyl-CpG binding domain protein 3) | protein interactions | 17192 | 2 | 2 | 17029 | 2761 |
SMARCA4,DNMT3A |
| 2.628e-02 | -3.64 | CCDC168 (coiled-coil domain containing 168) | protein interactions | 643677 | 2 | 2 | 17029 | 2761 |
CUL1,USO1 |
| 2.628e-02 | -3.64 | WARS2 (tryptophanyl tRNA synthetase 2, mitochondrial) | protein interactions | 10352 | 2 | 2 | 17029 | 2761 |
RMND5A,APP |
| 2.628e-02 | -3.64 | SRARP (steroid receptor associated and regulated protein) | protein interactions | 149563 | 2 | 2 | 17029 | 2761 |
SLC4A2,APP |
| 2.628e-02 | -3.64 | SUB1 (chromatin-binding transcription coactivator SUB1) | protein interactions | 855055 | 2 | 2 | 17029 | 2761 |
SUB1,BRCA1 |
| 2.628e-02 | -3.64 | Su(var)205 (Suppressor of variegation 205) | protein interactions | 34119 | 2 | 2 | 17029 | 2761 |
SMARCA4,TRIM28 |
| 2.628e-02 | -3.64 | BICC1 (BicC family RNA binding protein 1) | protein interactions | 80114 | 2 | 2 | 17029 | 2761 |
CAPZA2,TFG |
| 2.628e-02 | -3.64 | Ripk2 (receptor (TNFRSF)-interacting serine-threonine kinase 2) | protein interactions | 192656 | 2 | 2 | 17029 | 2761 |
SMURF1,SMAD4 |
| 2.628e-02 | -3.64 | Myo5b (myosin Vb) | protein interactions | 25132 | 2 | 2 | 17029 | 2761 |
RAB8A,RAB11A |
| 2.628e-02 | -3.64 | ZNF594 (zinc finger protein 594) | protein interactions | 84622 | 2 | 2 | 17029 | 2761 |
USP7,GOLGA2 |
| 2.628e-02 | -3.64 | DLX6-AS1 (DLX6 antisense RNA 1) | protein interactions | 285987 | 2 | 2 | 17029 | 2761 |
CDC23,GOLGA2 |
| 2.628e-02 | -3.64 | LOC100345293 (dnaJ homolog subfamily B member 1) | protein interactions | 100345293 | 2 | 2 | 17029 | 2761 |
SEC61B,SERP1 |
| 2.628e-02 | -3.64 | C15orf40 (chromosome 15 open reading frame 40) | protein interactions | 123207 | 2 | 2 | 17029 | 2761 |
METTL1,ERCC1 |
| 2.628e-02 | -3.64 | smo (smoothened) | protein interactions | 33196 | 2 | 2 | 17029 | 2761 |
PRKACA,CSNK1A1 |
| 2.628e-02 | -3.64 | LINC00673 (long intergenic non-protein coding RNA 673) | protein interactions | 100499467 | 2 | 2 | 17029 | 2761 |
PTPN11,PRPF19 |
| 2.628e-02 | -3.64 | IGKV1-5 (immunoglobulin kappa variable 1-5) | protein interactions | 28299 | 2 | 2 | 17029 | 2761 |
FUS,ARRB2 |
| 2.628e-02 | -3.64 | SPATA17 (spermatogenesis associated 17) | protein interactions | 128153 | 2 | 2 | 17029 | 2761 |
KRAS,KDM1B |
| 2.628e-02 | -3.64 | UBC12 (NEDD8-conjugating protein UBC12) | protein interactions | 851015 | 2 | 2 | 17029 | 2761 |
CUL1,RBX1 |
| 2.628e-02 | -3.64 | ETNPPL (ethanolamine-phosphate phospho-lyase) | protein interactions | 64850 | 2 | 2 | 17029 | 2761 |
APP,ZC3HC1 |
| 2.628e-02 | -3.64 | FANCM (Fanconi anemia complementation group M) | protein interactions | 100857997 | 2 | 2 | 17029 | 2761 |
RMI1,RMI2 |
| 2.628e-02 | -3.64 | ASNA1 (arsA arsenite transporter, ATP-binding, homolog 1 (bacterial)) | protein interactions | 100352737 | 2 | 2 | 17029 | 2761 |
SEC61B,SERP1 |
| 2.628e-02 | -3.64 | Lhx9 (LIM homeobox protein 9) | protein interactions | 16876 | 2 | 2 | 17029 | 2761 |
SMAD2,SMURF1 |
| 2.628e-02 | -3.64 | Diaph3 (diaphanous related formin 3) | protein interactions | 56419 | 2 | 2 | 17029 | 2761 |
RHOA,CDC42 |
| 2.628e-02 | -3.64 | TOGARAM1 (TOG array regulator of axonemal microtubules 1) | protein interactions | 23116 | 2 | 2 | 17029 | 2761 |
CEP104,SRPK2 |
| 2.628e-02 | -3.64 | Uvrag (UV radiation resistance associated gene) | protein interactions | 78610 | 2 | 2 | 17029 | 2761 |
BECN1,XRCC5 |
| 2.628e-02 | -3.64 | MACROD2 (MACRO domain containing 2) | protein interactions | 140733 | 2 | 2 | 17029 | 2761 |
TERF1,TERF2 |
| 2.628e-02 | -3.64 | BTBD8 (BTB domain containing 8) | protein interactions | 284697 | 2 | 2 | 17029 | 2761 |
WIPI2,CUL3 |
| 2.628e-02 | -3.64 | CDH1 (Cdh1p) | protein interactions | 852881 | 2 | 2 | 17029 | 2761 |
CCNB1,PTTG1 |
| 2.628e-02 | -3.64 | ZNF510 (zinc finger protein 510) | protein interactions | 22869 | 2 | 2 | 17029 | 2761 |
SMAD1,CDK11A |
| 2.628e-02 | -3.64 | FAM177A1 (family with sequence similarity 177 member A1) | protein interactions | 100355886 | 2 | 2 | 17029 | 2761 |
SEC61B,SERP1 |
| 2.628e-02 | -3.64 | Rb1cc1 (RB1-inducible coiled-coil 1) | protein interactions | 12421 | 2 | 2 | 17029 | 2761 |
MAP3K5,STMN1 |
| 2.628e-02 | -3.64 | FSD1L (fibronectin type III and SPRY domain containing 1 like) | protein interactions | 83856 | 2 | 2 | 17029 | 2761 |
LYN,APP |
| 2.628e-02 | -3.64 | MUC12 (mucin 12, cell surface associated) | protein interactions | 10071 | 2 | 2 | 17029 | 2761 |
CDC42,MAPK14 |
| 2.628e-02 | -3.64 | ZNF268 (zinc finger protein 268) | protein interactions | 10795 | 2 | 2 | 17029 | 2761 |
RBPJ,TRIM28 |
| 2.628e-02 | -3.64 | ZNF671 (zinc finger protein 671) | protein interactions | 79891 | 2 | 2 | 17029 | 2761 |
SIAH1,MAPK6 |
| 2.628e-02 | -3.64 | SLITRK4 (SLIT and NTRK like family member 4) | protein interactions | 139065 | 2 | 2 | 17029 | 2761 |
CNPY3,LYN |
| 2.628e-02 | -3.64 | Eef2 (eukaryotic translation elongation factor 2) | protein interactions | 13629 | 2 | 2 | 17029 | 2761 |
CUL1,PTEN |
| 2.628e-02 | -3.64 | KIAA0825 (KIAA0825) | protein interactions | 285600 | 2 | 2 | 17029 | 2761 |
APP,ILF3 |
| 2.628e-02 | -3.64 | HSPA8 (heat shock protein family A (Hsp70) member 8) | protein interactions | 100348873 | 2 | 2 | 17029 | 2761 |
SEC61B,SERP1 |
| 2.628e-02 | -3.64 | Bhlhe40 (basic helix-loop-helix family, member e40) | protein interactions | 20893 | 2 | 2 | 17029 | 2761 |
TCF3,PRKAA1 |
| 2.632e-02 | -3.64 | regulation of phosphatase activity | biological process | GO:0010921 | 172 | 36 | 17256 | 2622 |
PPP1R37,ZCCHC9,PPP1R2,PPP1R12A,PPP1R15B,ENSA,PPP1R16B,CALM2,PPP1R3B,FKBP1A,UBXN2A,PPP1R8,PPME1,PPP4R1,PPP1R12C,NSFL1C,CRY2,GNAI2,PPP6R1,CHP1,ANKLE2,SHOC2,PPP1R9B,WDR81,PKMYT1,PLEKHF2,MASTL,TSC1,PPP2R5A,UBXN2B,PPP1R11,CABIN1,ROCK1,PPP6R3,IGBP1,PPP2R2D |
| 2.632e-02 | -3.64 | glycerolipid biosynthetic process | biological process | GO:0045017 | 246 | 49 | 17256 | 2622 |
RAB14,PIGM,CDS2,PIGN,PIGQ,AGPAT1,STARD7,CSNK2A1,AGPAT3,ARF1,CHKB,CDIPT,LCLAT1,RUFY1,PIP4K2A,CPNE3,PIP5K1C,CHKA,FGFR3,PDXP,PYURF,MTMR4,PTEN,PIK3R2,SLC44A1,LPIN2,RAB4A,PTPN11,PIGG,PCYT2,PIKFYVE,LPCAT1,GPD1L,PGAP2,CPNE1,PIGT,DPM1,PGS1,PIP4K2C,MTMR6,MTMR12,TAZ,PI4K2A,ABHD5,MTMR3,AGPAT2,LPCAT4,CHPT1,PTDSS1 |
| 2.633e-02 | -3.64 | oxidoreductase activity, acting on the CH-CH group of donors | molecular function | GO:0016627 | 58 | 15 | 17224 | 2647 |
SDHB,DECR1,COX15,DUS4L,DUS3L,ACOX1,CPOX,MECR,DUS2,ACADM,ACAD8,TECR,ZADH2,SDHA,RSAD1 |
| 2.635e-02 | -3.64 | GINESTIER_BREAST_CANCER_20Q13_AMPLIFICATION_UP | MSigDB lists | GINESTIER_BREAST_CANCER_20Q13_AMPLIFICATION_UP | 101 | 23 | 17377 | 2626 |
STAU1,RHOBTB3,ADD1,TMBIM4,DPM1,MUM1,KCTD20,RIT1,AZI2,STX16,EBP,RDH11,KIF5B,DLG5,CTNNBL1,MAGT1,ERGIC3,RAD23B,EFCAB11,RBM3,F2R,SNX14,SYTL3 |
| 2.637e-02 | -3.64 | Herpes simplex infection | KEGG pathways | hsa05168 | 185 | 40 | 7161 | 1149 |
DDX58,USP7,HLA-E,SRSF6,TAP1,CSNK2A1,CUL1,CYCS,IRF3,TAF6L,EIF2AK4,HLA-A,MED8,SP100,SRSF4,PTPN11,TAP2,TAF5L,MAVS,EEF1D,HMGN1,EIF2AK1,SRSF5,POLR2A,FADD,SRSF1,FAS,HLA-B,JAK1,TAB2,ARNTL,STAT1,PML,TBPL1,TICAM1,SRSF3,RNASEL,TAF6,TRAF5,CDK2 |
| 2.637e-02 | -3.64 | Herpes simplex infection | KEGG pathways | ko05168 | 185 | 40 | 7161 | 1149 |
DDX58,USP7,HLA-E,SRSF6,TAP1,CSNK2A1,CUL1,CYCS,IRF3,TAF6L,EIF2AK4,HLA-A,MED8,SP100,SRSF4,PTPN11,TAP2,TAF5L,MAVS,EEF1D,HMGN1,EIF2AK1,SRSF5,POLR2A,FADD,SRSF1,FAS,HLA-B,JAK1,TAB2,ARNTL,STAT1,PML,TBPL1,TICAM1,SRSF3,RNASEL,TAF6,TRAF5,CDK2 |
| 2.638e-02 | -3.64 | human chr17q21.33 | chromosome location | human chr17q21.33 | 54 | 11 | 26185 | 2809 |
PPP1R9B,PDK2,UTP18,KAT7,LUC7L3,MRPL27,SLC35B1,LRRC59,RSAD1,ACSF2,TOB1 |
| 2.639e-02 | -3.63 | skin-malignant_melanoma-acral_lentiginous | COSMIC cancer mutations | skin-malignant_melanoma-acral_lentiginous | 30 | 9 | 17385 | 2587 |
FGFR3,RB1,NRAS,PTEN,SF3B1,KRAS,MEN1,HRAS,CDKN2A |
| 2.639e-02 | -3.63 | ovary-carcinoma-carcinosarcoma-malignant_mesodermal_mixed_tumour | COSMIC cancer mutations | ovary-carcinoma-carcinosarcoma-malignant_mesodermal_mixed_tumour | 30 | 9 | 17385 | 2587 |
RB1,KRAS,BRCA1,NRAS,NF1,PTEN,SMAD4,CDKN2A,MSH2 |
| 2.643e-02 | -3.63 | Cyclin_C | smart domains | SM01332 | 17 | 6 | 9493 | 1367 |
CCNK,CCNA2,CCNL2,CCNF,CCNB1,CCNB2 |
| 2.643e-02 | -3.63 | REACTOME_SMAD2_SMAD3_SMAD4_HETEROTRIMER_REGULATES_TRANSCRIPTION | MSigDB lists | REACTOME_SMAD2_SMAD3_SMAD4_HETEROTRIMER_REGULATES_TRANSCRIPTION | 25 | 8 | 17377 | 2626 |
CCNC,SMAD2,MEN1,RBL1,RPS27A,SMAD4,E2F4,TFDP1 |
| 2.643e-02 | -3.63 | MODULE_307 | MSigDB lists | MODULE_307 | 25 | 8 | 17377 | 2626 |
COX5B,ATP6V0B,COX8A,COX5A,COX4I1,ATP6V0C,ATP6V1B2,ATP6V1C1 |
| 2.643e-02 | -3.63 | GO_REGULATION_OF_MRNA_CATABOLIC_PROCESS | MSigDB lists | GO_REGULATION_OF_MRNA_CATABOLIC_PROCESS | 25 | 8 | 17377 | 2626 |
SECISBP2,UPF1,POLR2G,HNRNPR,BTG2,TOB1,PABPC1,ZC3HAV1 |
| 2.643e-02 | -3.63 | GO_DNA_STRAND_ELONGATION_INVOLVED_IN_DNA_REPLICATION | MSigDB lists | GO_DNA_STRAND_ELONGATION_INVOLVED_IN_DNA_REPLICATION | 25 | 8 | 17377 | 2626 |
GINS1,POLA2,RFC3,PCNA,PRIM2,RNASEH2A,GINS4,PRIM1 |
| 2.643e-02 | -3.63 | MODULE_306 | MSigDB lists | MODULE_306 | 25 | 8 | 17377 | 2626 |
SDHB,SUCLG1,LDHA,MDH1,IDH3B,PGAM1,SDHA,PFKP |
| 2.643e-02 | -3.63 | GO_NUCLEOTIDE_TRANSPORT | MSigDB lists | GO_NUCLEOTIDE_TRANSPORT | 25 | 8 | 17377 | 2626 |
SLC35B4,SLC25A19,SLC35B2,SLC35B1,SLC35C2,SLC35A1,SLC25A33,SLC25A36 |
| 2.643e-02 | -3.63 | GO_REGULATION_OF_NECROTIC_CELL_DEATH | MSigDB lists | GO_REGULATION_OF_NECROTIC_CELL_DEATH | 25 | 8 | 17377 | 2626 |
ARHGEF2,PPIF,HEBP2,BIRC3,RPS27A,BIRC2,FADD,CFLAR |
| 2.643e-02 | -3.63 | GO_CUL4_RING_E3_UBIQUITIN_LIGASE_COMPLEX | MSigDB lists | GO_CUL4_RING_E3_UBIQUITIN_LIGASE_COMPLEX | 25 | 8 | 17377 | 2626 |
DTL,DCAF6,RBX1,DCAF8,DCAF11,CDKN1B,DCAF5,DDB1 |
| 2.643e-02 | -3.63 | GAZIN_EPIGENETIC_SILENCING_BY_KRAS | MSigDB lists | GAZIN_EPIGENETIC_SILENCING_BY_KRAS | 25 | 8 | 17377 | 2626 |
PDPK1,CTCF,BAZ2A,MAPK1,EID1,DNMT1,E2F1,DOT1L |
| 2.643e-02 | -3.63 | BIOCARTA_MCALPAIN_PATHWAY | MSigDB lists | BIOCARTA_MCALPAIN_PATHWAY | 25 | 8 | 17377 | 2626 |
CAPN2,PRKAR1B,ITGB1,EZR,MAPK1,HRAS,CAPN1,MAPK3 |
| 2.644e-02 | -3.63 | ATPase_proteolipid_c-like_dom | interpro domains | IPR002379 | 5 | 3 | 18492 | 2768 |
ATP6V0B,ATP6V0C,ATP5MC3 |
| 2.644e-02 | -3.63 | CobW/HypB/UreG_dom | interpro domains | IPR003495 | 5 | 3 | 18492 | 2768 |
CBWD1,CBWD2,CBWD5 |
| 2.644e-02 | -3.63 | F/V-ATP_Csub_sf | interpro domains | IPR035921 | 5 | 3 | 18492 | 2768 |
ATP6V0B,ATP6V0C,ATP5MC3 |
| 2.644e-02 | -3.63 | DZF_dom | interpro domains | IPR006561 | 5 | 3 | 18492 | 2768 |
STRBP,ZFR,ILF3 |
| 2.644e-02 | -3.63 | Nas_poly-pep-assoc_cplx_dom | interpro domains | IPR002715 | 5 | 3 | 18492 | 2768 |
BTF3,NACA,BTF3L4 |
| 2.644e-02 | -3.63 | SPOC-like_C_dom_sf | interpro domains | IPR016194 | 5 | 3 | 18492 | 2768 |
RBM15,XRCC5,RBM15B |
| 2.644e-02 | -3.63 | YTH_domain | interpro domains | IPR007275 | 5 | 3 | 18492 | 2768 |
YTHDF3,YTHDC1,YTHDC2 |
| 2.644e-02 | -3.63 | NAC_A/B_dom_sf | interpro domains | IPR038187 | 5 | 3 | 18492 | 2768 |
BTF3,NACA,BTF3L4 |
| 2.644e-02 | -3.63 | CobW-likC_sf | interpro domains | IPR036627 | 5 | 3 | 18492 | 2768 |
CBWD1,CBWD2,CBWD5 |
| 2.644e-02 | -3.63 | HnRNP_R/Q_splicing_fac | interpro domains | IPR006535 | 5 | 3 | 18492 | 2768 |
RBM47,SYNCRIP,HNRNPR |
| 2.644e-02 | -3.63 | ATPase_F1/V1/A1_a/bsu_N | interpro domains | IPR004100 | 5 | 3 | 18492 | 2768 |
ATP5F1A,ATP5F1B,ATP6V1B2 |
| 2.644e-02 | -3.63 | Porin_Euk/Tom40 | interpro domains | IPR027246 | 5 | 3 | 18492 | 2768 |
VDAC1,TOMM40,VDAC2 |
| 2.644e-02 | -3.63 | PUA | interpro domains | IPR002478 | 5 | 3 | 18492 | 2768 |
NIP7,EIF2D,MCTS1 |
| 2.644e-02 | -3.63 | Znf_Rad18_put | interpro domains | IPR006642 | 5 | 3 | 18492 | 2768 |
RAD18,POLK,WRNIP1 |
| 2.644e-02 | -3.63 | HRDC-like_sf | interpro domains | IPR010997 | 5 | 3 | 18492 | 2768 |
CRCP,BLM,POLR2D |
| 2.644e-02 | -3.63 | ATPase_a/bsu_AS | interpro domains | IPR020003 | 5 | 3 | 18492 | 2768 |
ATP5F1A,ATP5F1B,ATP6V1B2 |
| 2.644e-02 | -3.63 | ATPase_F1/V1/A1_a/bsu_nucl-bd | interpro domains | IPR000194 | 5 | 3 | 18492 | 2768 |
ATP5F1A,ATP5F1B,ATP6V1B2 |
| 2.644e-02 | -3.63 | SMC | interpro domains | IPR024704 | 5 | 3 | 18492 | 2768 |
SMC3,SMC2,SMC4 |
| 2.644e-02 | -3.63 | Cbl_biosynth_CobW-like_C | interpro domains | IPR011629 | 5 | 3 | 18492 | 2768 |
CBWD1,CBWD2,CBWD5 |
| 2.646e-02 | -3.63 | Translesion Synthesis by POLH | REACTOME pathways | R-HSA-110320 | 19 | 7 | 10287 | 1696 |
RPA2,PCNA,RFC3,RFC2,RPS27A,NPLOC4,RPA1 |
| 2.646e-02 | -3.63 | Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase | REACTOME pathways | R-HSA-176407 | 19 | 7 | 10287 | 1696 |
ANAPC2,ANAPC7,CDC16,CDC23,CDC27,UBE2C,ANAPC4 |
| 2.646e-02 | -3.63 | TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest | REACTOME pathways | R-HSA-6804114 | 19 | 7 | 10287 | 1696 |
PCNA,TFDP2,CCNB1,RBL1,E2F4,TFDP1,CARM1 |
| 2.650e-02 | -3.63 | GO_TRANSCRIPTION_FACTOR_COMPLEX | MSigDB lists | GO_TRANSCRIPTION_FACTOR_COMPLEX | 294 | 57 | 17377 | 2626 |
POU3F2,TCF12,HNRNPAB,TRERF1,IVNS1ABP,TCF3,MEF2A,PMF1,ETS1,RCOR3,SNAPC4,GTF2F1,CREM,RB1,USF1,SUB1,MED10,CD3EAP,TAF5L,CREB1,STAT3,GTF2H2,CARM1,GTF3C6,ERCC1,DEAF1,KAT2A,CREG1,MTA2,PRKDC,LDB1,E2F3,RCOR1,NFATC2,EDF1,SOX4,PRMT2,TRIM28,TAF2,SMAD2,PDLIM1,RBL1,HIPK2,E2F4,TFDP1,PITX1,ARNTL,TBPL1,E2F1,RBPJ,TAF12,TFDP2,SMAD1,CDK2,E2F2,TAF6,SMAD4 |
| 2.651e-02 | -3.63 | GSE29618_BCELL_VS_MDC_DAY7_FLU_VACCINE_DN | MSigDB lists | GSE29618_BCELL_VS_MDC_DAY7_FLU_VACCINE_DN | 190 | 39 | 17377 | 2626 |
PTMS,CKLF,FAM129A,RHOC,HEXB,PARK7,LMNA,SSR1,FKBP1A,DST,DPYSL2,ATG3,DAPK1,H2AFY,CLTB,TIPARP,IMPA2,PPIF,CYFIP1,KLF10,MAPKAPK3,PPT1,CREG1,RAB7A,LDHA,RCOR1,MCL1,PTTG1IP,SLC25A5,CAT,PON2,AHNAK,ETS2,DUSP3,ACTB,PSAP,RUFY3,TOB1,AP2S1 |
| 2.651e-02 | -3.63 | GSE3720_VD1_VS_VD2_GAMMADELTA_TCELL_DN | MSigDB lists | GSE3720_VD1_VS_VD2_GAMMADELTA_TCELL_DN | 190 | 39 | 17377 | 2626 |
MIF,PTMS,PLXNC1,MRPL42,SRGN,UCK2,AKT1S1,POMP,RGS2,STMN1,TMEM165,LCLAT1,TUBGCP2,RGS1,MEAF6,TMEM179B,RPN1,PTPN11,MAST2,TACC3,POU2AF1,FYTTD1,TIMM8B,TK1,SNX2,PFKFB3,TOR1AIP2,VDAC1,KIF11,TTC33,MAT2A,DPYSL3,BIRC5,CDCA5,DBI,PPM1G,RUFY3,TATDN1,OSGEPL1 |
| 2.651e-02 | -3.63 | GO_NUCLEASE_ACTIVITY | MSigDB lists | GO_NUCLEASE_ACTIVITY | 190 | 39 | 17377 | 2626 |
PMS2,TATDN3,SND1,PARN,NEIL2,EDC3,MBD4,EXOSC7,PPP1R8,RNASEK,POP7,PELO,EXOSC1,XRCC2,RNASEH2A,ERI3,CNOT6L,OGG1,N4BP2,RPP25,TDP1,ERCC1,EXOSC6,RNASEH2C,EXOSC9,DCLRE1C,RAD51C,POLE,DGCR8,TATDN2,NEIL3,AEN,CNOT6,XRCC3,RNASEL,TATDN1,GEN1,TSEN15,RAD51D |
| 2.651e-02 | -3.63 | GSE3337_CTRL_VS_4H_IFNG_IN_CD8POS_DC_DN | MSigDB lists | GSE3337_CTRL_VS_4H_IFNG_IN_CD8POS_DC_DN | 190 | 39 | 17377 | 2626 |
GPR132,HNRNPAB,TOR3A,GADD45G,TAP1,PPP3CB,SNRPD3,GGPS1,TCF19,BZW2,CDC73,CPNE3,MXD1,PAPOLA,TPST1,ARHGEF2,MRPL54,FBL,PDIA6,STAT3,PABPC1,ABCC1,TNFAIP3,RAB7A,USP22,PSMB9,CAND1,STOML2,RBL1,STAT1,CEBPG,PML,AP1S1,FAU,CHPT1,RNF14,CSNK1D,TUBB,PFKP |
| 2.651e-02 | -3.63 | GSE8685_IL2_ACT_IL2_STARVED_VS_IL15_ACT_IL2_STARVED_CD4_TCELL_UP | MSigDB lists | GSE8685_IL2_ACT_IL2_STARVED_VS_IL15_ACT_IL2_STARVED_CD4_TCELL_UP | 190 | 39 | 17377 | 2626 |
CHMP2A,SKA3,MRPL9,GPR132,COPA,CHERP,GGA1,CAST,TAP1,B4GALT1,ZNRF3,DOCK11,CRLF3,ARID1B,ANKRD39,NUP210,VMP1,DDA1,ARHGEF1,ZNF672,KIAA0040,CIC,SLC26A6,ANAPC2,MCL1,SLC17A5,ASB13,BUD13,RPS9,BSDC1,VEZF1,PDLIM1,APPL2,ARAP1,USP20,PRPF4,ST3GAL2,FAM208A,PGAM1 |
| 2.651e-02 | -3.63 | GSE20715_WT_VS_TLR4_KO_LUNG_UP | MSigDB lists | GSE20715_WT_VS_TLR4_KO_LUNG_UP | 190 | 39 | 17377 | 2626 |
UBE2D3,IMMT,PARP12,ST13,PLXNC1,FAM129A,ANKH,TM9SF3,ZFYVE21,MEF2A,GLUD1,SLC35B1,AP3S1,MAP1LC3B,RAPGEF6,TMCC3,CSDE1,CDKN2C,FANCL,CLIC4,VMP1,RRBP1,TARDBP,APOOL,SNX2,IDH3A,CUL3,RABIF,MTMR6,SURF4,TMEM168,JAK1,TWSG1,TMED10,SNAP23,DDX5,ST3GAL2,MAPK1,RPS26 |
| 2.651e-02 | -3.63 | GSE17721_LPS_VS_GARDIQUIMOD_8H_BMDC_UP | MSigDB lists | GSE17721_LPS_VS_GARDIQUIMOD_8H_BMDC_UP | 190 | 39 | 17377 | 2626 |
KARS,MCM10,TPX2,CHAC2,POMP,DNAJB1,ANKIB1,NUDT19,IRF4,SSBP3,CDKN1B,STAT3,TIPARP,HTRA2,POLR2G,HMGN5,GTPBP4,DNAJA1,TANC1,ASB13,PSMB9,USP21,RAB22A,ARF4,NMT2,PLEKHF2,CAND1,PI4K2A,HLA-B,MBIP,PCM1,CDC27,GADD45B,PIAS2,IMPDH1,IGBP1,RNF14,TSPAN5,ANXA11 |
| 2.651e-02 | -3.63 | GSE23505_IL6_IL1_IL23_VS_IL6_IL1_TGFB_TREATED_CD4_TCELL_UP | MSigDB lists | GSE23505_IL6_IL1_IL23_VS_IL6_IL1_TGFB_TREATED_CD4_TCELL_UP | 190 | 39 | 17377 | 2626 |
CCNC,GALK1,MRPL9,PDCD6IP,GNPNAT1,ANXA6,KIAA0100,MRPL39,FAM53C,BZW2,RAD23A,DDRGK1,FERMT3,WWP2,C12orf10,SUV39H2,SNX18,RNASEK,BCL2,CYB5R1,ERI3,MOB1A,CAMK2G,ATP13A1,NOA1,PSPC1,MAN1B1,RCOR1,NDUFA7,OGFR,EIF3K,CSK,UBXN2B,TCOF1,RNASEL,SPRYD4,TAF12,EHD4,TSEN15 |
| 2.651e-02 | -3.63 | GSE27786_CD4_TCELL_VS_NKTCELL_UP | MSigDB lists | GSE27786_CD4_TCELL_VS_NKTCELL_UP | 190 | 39 | 17377 | 2626 |
GMFG,SF3B1,CDK2AP2,AP3M2,CDC42SE2,DCUN1D4,MAP1LC3B,CRLF3,METTL3,HMG20A,KIF5B,DPYSL2,JAZF1,PHF14,BUD31,ZNF326,TIMELESS,KIFAP3,RNASEH2A,ARL5A,SMC4,FDFT1,YTHDC1,MIER1,WDR82,AP4E1,DHX15,TWISTNB,RPA1,PAF1,MAN2A2,SDHB,DAP3,ETS2,L3MBTL3,SETD3,DCAF11,HMGB2,S100PBP |
| 2.651e-02 | -3.63 | GSE25088_CTRL_VS_ROSIGLITAZONE_STIM_MACROPHAGE_UP | MSigDB lists | GSE25088_CTRL_VS_ROSIGLITAZONE_STIM_MACROPHAGE_UP | 190 | 39 | 17377 | 2626 |
PWWP2A,TCF12,ST13,COPA,KCMF1,MAT2B,MOAP1,LIN9,RNF121,ZNF420,BDH1,DDX31,TARDBP,CHTOP,SPTSSA,NUP85,PPA1,HNRNPM,CSNK1G3,PRIM2,BTG2,GMFB,UTP15,ADRB2,AURKB,FOXRED1,APPL1,MTHFD2,FBXO28,CCDC6,TWSG1,ZNF330,UBXN2B,E2F1,LRPPRC,MRFAP1L1,KPNA2,CWC25,FAM72A |
| 2.651e-02 | -3.63 | GSE41978_ID2_KO_VS_BIM_KO_KLRG1_LOW_EFFECTOR_CD8_TCELL_DN | MSigDB lists | GSE41978_ID2_KO_VS_BIM_KO_KLRG1_LOW_EFFECTOR_CD8_TCELL_DN | 190 | 39 | 17377 | 2626 |
PPIB,DNAJC2,PDCD6IP,NDUFB6,DCAF15,ZNF768,UBR2,SNN,POLR3K,HNRNPA2B1,RAP1A,MDM2,CWC27,RABGAP1L,MECR,FEM1B,RPN2,CDK12,CFL1,FTL,SEC61B,FAM49B,PPT1,EAF2,IL12RB1,BICD2,FXR1,MPG,MCFD2,EIF4H,EIF4G2,ZFAND5,EIF3A,PSMC4,MAGED2,SEC61A1,SIL1,RUVBL2,CCDC59 |
| 2.651e-02 | -3.63 | GSE7852_LN_VS_FAT_TREG_DN | MSigDB lists | GSE7852_LN_VS_FAT_TREG_DN | 190 | 39 | 17377 | 2626 |
SRGN,WDTC1,KIF23,DNAJB9,EPM2A,CAPN2,DLG5,ATP2A2,KIFAP3,PLCL2,TMBIM1,IMPA2,DCTN1,SAP30,ELOVL5,GALC,ELL2,MAPKAPK3,EMB,PLEC,IL12RB1,IRF5,RHOB,VEZF1,AHNAK,GALNT2,MID1IP1,ETS2,AGPAT2,BRD2,DUSP3,TPP2,MEGF9,PKD2,RBPJ,ARHGAP23,TOB1,EYA2,ZC3HAV1 |
| 2.651e-02 | -3.63 | GSE21927_SPLEEN_VS_BONE_MARROW_MONOCYTE_BALBC_DN | MSigDB lists | GSE21927_SPLEEN_VS_BONE_MARROW_MONOCYTE_BALBC_DN | 173 | 36 | 17377 | 2626 |
TXN,FAM129A,ANK3,USP48,ABHD14A,JMY,FERMT3,RTKN,JAKMIP1,ZNF804A,NUDT19,NT5DC1,MCM5,GNAI2,CNPY3,F2R,DDX28,TRAPPC9,CSRP1,RNASEH2C,TMEM216,TMEM147,MCM2,HAUS8,PEX5,PDLIM1,CCDC86,DUSP3,HIPK2,COX7A2L,ZFP90,DVL1,PDCD2L,TOB1,NIPA1,SSRP1 |
| 2.651e-02 | -3.63 | GSE34205_HEALTHY_VS_RSV_INF_INFANT_PBMC_UP | MSigDB lists | GSE34205_HEALTHY_VS_RSV_INF_INFANT_PBMC_UP | 173 | 36 | 17377 | 2626 |
ST13,MPHOSPH8,UBN1,NACA,ANKH,UBE2Z,MXD4,PABPC4,MEAF6,KIAA1147,MBD4,CEP104,IMPAD1,AKR1B1,RPL19,FBL,MYBL1,CNNM3,EIF3L,RPL35,ZMYND11,RPL8,TUFM,RPS10,ADRB2,TRIM28,QARS,HIPK2,BBX,GLG1,ARAP1,YY1,SNRNP70,MAPK1,PTDSS1,LRP8 |
| 2.658e-02 | -3.63 | CTTTGT_V$LEF1_Q2 | MSigDB lists | CTTTGT_V$LEF1_Q2 | 1828 | 305 | 17377 | 2626 |
ZNF496,TSC22D3,TMEM109,CUL1,GLUD1,CCNL2,UBE2I,EIF1B,PPP1R16B,CALM2,USF1,ASAP2,FIZ1,AP2B1,UPRT,SMARCE1,USP34,ZNF524,USO1,RHOBTB3,NRAS,WBP1,ZFAND5,CBFB,RAB22A,ANKRD10,SMAD2,WDR11,LUC7L3,OGT,ST3GAL2,PTPDC1,BTF3,TFDP2,SMAD1,ARRB2,RTN3,PDCD4,HDAC2,DDX42,PTOV1,WSB2,HSPH1,VAV2,ANKH,DLGAP4,DHX9,SLC4A2,TMED3,SLC35B1,NOTCH2,ITGB5,MYL6B,MCTS1,RTKN,FAM192A,TFAP4,MEX3C,KLHL5,PPP4R1,DAPK1,PCYT2,MRPL40,TMED2,MORC3,SOCS5,CYFIP1,FTL,RB1CC1,PRRC2A,MTA2,ARID1A,MTX1,PLEC,RIT1,ADRB2,CYFIP2,KDM3A,RHOB,ADSS,SEC31A,PDLIM1,RBMX,SLAIN1,TCOF1,MAP3K5,RUFY3,NUDT3,DNMT3A,IVNS1ABP,POC1A,SF3B1,ACTR3,ANK3,ADPGK,BCL2L1,SNN,STMN1,KTN1,APP,PAIP2,CRKL,MOAP1,PHC2,DDA1,NUP107,INTS12,FAM76B,TMEM136,CDK12,SAP30,CPNE1,CCT2,KAT7,LYRM1,MAP4K4,NARF,ATP6V0A1,PFKFB3,GALK2,DNAJA1,MEF2D,GSTCD,TAZ,EML4,ERC1,MAT2A,DHX57,DDX17,C19orf54,KIF2A,VEZF1,SEC61A1,CERS6,RNF38,RBMS1,LRP8,TUBB,RHEBL1,ANXA6,SCAMP3,SESTD1,ZFP91,CDCA3,IP6K2,RAB11A,FOXO3,WWP2,GOLM1,PSMD2,ZBTB45,PDCD10,ADD3,ITGB8,FUT8,FJX1,AXIN2,MAP3K14,CITED2,ST8SIA2,HNRNPM,ILF3,PACS1,C14orf132,RPL27A,PICALM,POLR2A,CBX3,SH3BP5,SLC38A7,GPS2,HNRNPH3,OAZ2,MAPK6,DDX5,YWHAH,PURA,S100PBP,RORB,PTMS,HNRNPAB,PLXNC1,S1PR2,KCMF1,DST,PCNA,CDC42,TIMM23,DPYSL2,XRCC2,SLC44A1,ETV6,JOSD1,DRAM2,RYBP,ABCC5,MIOS,BAZ2A,TLK1,ZBED5,SLC25A22,LRP5,PBRM1,KRTCAP2,ODC1,LUC7L,DPYSL3,UBTF,CXXC4,FBXO28,BCL7C,ACTB,FAM208A,NUMB,PPP1R12A,CENPF,TIA1,CTCF,RAB6A,XPO7,NFATC3,SSBP3,BUD31,FAM89B,CTR9,YBX1,NIPSNAP1,ABHD2,LDB1,KRAS,RTF1,EIF4G2,TSC1,SYNCRIP,NFIL3,TBPL1,FAM122A,SLC16A1,YWHAZ,TOB1,TIGD2,TCF12,WASF2,SMARCA4,PCBP1,CHD1,PAIP1,USP5,CSDE1,TMEM69,HNRNPA2B1,CCDC50,PPME1,CS,METTL9,AHCYL1,F2R,ABI1,ZNF583,MOSPD1,KDM3B,MND1,BTG2,SLC26A6,NLN,CHMP2B,ARL5B,RAD54B,HNRNPR,PROSER1,UHRF2,FKBP5,H3F3A,TSPAN5,ATXN7L2,EYA1,ARID5A,ARFIP2,KLF13,DCUN1D4,BZW2,XPR1,GSTK1,FGFR3,ZDHHC13,ANP32A,ARHGEF2,H2AFY,DDX31,STAT3,PPP1R9B,HMGN5,TMEM39A,ATP2C1,CCDC34,RCOR1,WDR81,SNRPA,FAM110A,BBX,SRSF3,RBPJ,ZMIZ1,NR2F2,CHMP7 |
| 2.660e-02 | -3.63 | GO_REGULATION_OF_PHOSPHOLIPID_METABOLIC_PROCESS | MSigDB lists | GO_REGULATION_OF_PHOSPHOLIPID_METABOLIC_PROCESS | 59 | 15 | 17377 | 2626 |
TGFB1,FGFR3,CDC42,PIK3R2,VAV2,ACSL3,RAC1,PIK3IP1,ARF1,SCARB1,ZP3,LYN,LPCAT1,CD81,STOML2 |
| 2.660e-02 | -3.63 | ACATATC,MIR-190 | MSigDB lists | ACATATC,MIR-190 | 59 | 15 | 17377 | 2626 |
TSHZ1,PHF20L1,HECA,ARPC5,WDR44,TBC1D14,ACTR3,CDKN1B,YTHDF3,SMC6,CADM1,ARF4,MYO5A,RLIM,SRSF1 |
| 2.660e-02 | -3.63 | GCM_CRKL | MSigDB lists | GCM_CRKL | 59 | 15 | 17377 | 2626 |
CRKL,KDM3B,ZNF84,GOLGA7,MTMR4,IL6ST,MAP4K4,OAZ2,ADO,ALKBH5,CS,CHTOP,HMG20A,PACS2,DDX17 |
| 2.661e-02 | -3.63 | GSE5589_WT_VS_IL10_KO_LPS_AND_IL10_STIM_MACROPHAGE_180MIN_UP | MSigDB lists | GSE5589_WT_VS_IL10_KO_LPS_AND_IL10_STIM_MACROPHAGE_180MIN_UP | 145 | 31 | 17377 | 2626 |
GINS1,NOL12,JMJD4,CHMP2A,HEMK1,RHOA,GGA1,MAGED1,SLC16A7,VPS45,ADSL,RACGAP1,PXMP2,ADRB2,UBQLN2,ZADH2,HDDC2,MXD1,RPA1,APLP2,KIF18A,CTNNBL1,SNAP23,PRC1,RNF38,CRCP,ECD,RNF19A,NAA20,NDE1,TIGD2 |
| 2.667e-02 | -3.62 | RHOXF2 (Rhox homeobox family member 2) | protein interactions | 84528 | 60 | 16 | 17029 | 2761 |
POU2AF1,EWSR1,MAGED1,ARID5A,ATXN1,DAZAP2,UBE2I,TOLLIP,VPS25,CCNK,UPF1,SERF2,PITX1,MVP,PLOD3,DVL2 |
| 2.667e-02 | -3.62 | PGAM5 (PGAM family member 5, mitochondrial serine/threonine protein phosphatase) | protein interactions | 192111 | 60 | 16 | 17029 | 2761 |
KEAP1,CYLD,EIF4A3,RBX1,HUWE1,SUZ12,ZNF746,XIAP,CUL3,BRCA1,BCL2L1,ZRANB1,USP11,CDK2,BIRC2,HSPA1B |
| 2.670e-02 | -3.62 | human chr19q13.2 | chromosome location | human chr19q13.2 | 156 | 25 | 26185 | 2809 |
SAMD4B,TGFB1,GMFG,ZNF780B,ERF,CIC,AKT2,DMAC2,ZNF574,SIRT2,SNRPA,ECH1,PSMC4,PAF1,EIF3K,C19orf54,PLD3,LTBP4,RINL,PSMD8,MEGF8,ARHGEF1,YIF1B,FBL,TIMM50 |
| 2.672e-02 | -3.62 | SCHAEFFER_SOX9_TARGETS_IN_PROSTATE_DEVELOPMENT_DN | MSigDB lists | SCHAEFFER_SOX9_TARGETS_IN_PROSTATE_DEVELOPMENT_DN | 44 | 12 | 17377 | 2626 |
TRIM8,NASP,CDC27,RRM2,YWHAZ,SOX4,STMN1,ETS1,CDK2,EIF3A,PHF6,NUDT3 |
| 2.672e-02 | -3.62 | GO_POSITIVE_REGULATION_OF_DEPHOSPHORYLATION | MSigDB lists | GO_POSITIVE_REGULATION_OF_DEPHOSPHORYLATION | 44 | 12 | 17377 | 2626 |
CALM2,TGFB1,ANKLE2,PPP2R5A,PPP1R12A,PIN1,GBA,CDCA2,PAWR,IGBP1,PPP1R16B,SYMPK |
| 2.672e-02 | -3.62 | GO_LIGASE_ACTIVITY_FORMING_CARBON_OXYGEN_BONDS | MSigDB lists | GO_LIGASE_ACTIVITY_FORMING_CARBON_OXYGEN_BONDS | 44 | 12 | 17377 | 2626 |
FARSA,KARS,EPRS,LARS,IARS,HARS,MRPL39,QARS,IARS2,POLG2,TARS,CARS2 |
| 2.676e-02 | -3.62 | GLYHDRLASE47 | prints domains | PR00747 | 7 | 3 | 4652 | 473 |
EDEM2,MAN1B1,MAN1A1 |
| 2.679e-02 | -3.62 | HOSHIDA_LIVER_CANCER_SUBCLASS_S2 | MSigDB lists | HOSHIDA_LIVER_CANCER_SUBCLASS_S2 | 112 | 25 | 17377 | 2626 |
TM9SF4,NET1,SUZ12,TIA1,CSNK2A1,RPS24,GLUD1,ABCB10,BCLAF1,POFUT1,CHKA,HNRNPA2B1,FGFR3,ADD3,TRIM26,PRDX3,MAPK6,RAB4A,TTC3,AHCY,NUP153,TP53BP2,FBL,ATF2,PTOV1 |
| 2.685e-02 | -3.62 | MAPK (ERK1/2) signaling | KEGG pathways | M00687 | 8 | 4 | 7161 | 1149 |
MAPK1,RAF1,MAP2K2,MAPK3 |
| 2.685e-02 | -3.62 | MAPK (ERK1/2) signaling | KEGG pathways | hsa_M00687 | 8 | 4 | 7161 | 1149 |
MAPK1,RAF1,MAP2K2,MAPK3 |
| 2.686e-02 | -3.62 | CAGCCTC,MIR-485-5P | MSigDB lists | CAGCCTC,MIR-485-5P | 134 | 29 | 17377 | 2626 |
YTHDC1,ABHD2,MAX,CELSR2,BAZ2A,DCAF15,TSC22D3,FAM53C,ZFP91,RAC1,WDTC1,STRN4,MIER2,LRRC1,MEF2D,PLEC,DHX57,MAN1A1,SUGP1,NRF1,NUCB1,INPP5A,TRMU,FOXN2,PPP1R11,COPS7B,ZMIZ1,RHBDD2,HTRA2 |
| 2.687e-02 | -3.62 | CHUK (conserved helix-loop-helix ubiquitous kinase) | protein interactions | 1147 | 146 | 33 | 17029 | 2761 |
NCOR2,KLHL21,MAGED1,TPX2,CUL1,CSNK2A1,UBE2I,PSMD9,FOXO3,CDC73,TANK,PTPN11,BCL2,MAP3K14,EBAG9,CDC37,SRPK2,BIRC3,TNFAIP3,PRKDC,DHX29,ERBIN,ERC1,IRF5,PAF1,PPP2CA,MAP3K4,SMAD2,TAB2,NLRC5,FKBP5,CLU,ARRB2 |
| 2.688e-02 | -3.62 | PID_RAC1_PATHWAY | MSigDB lists | PID_RAC1_PATHWAY | 54 | 14 | 17377 | 2626 |
WASF2,ARPC5,LIMK1,RAC1,ACTR3,RACGAP1,NCKAP1,CYFIP2,MAPK14,STAT3,ATF2,ABI1,CFL1,PIP5K1C |
| 2.694e-02 | -3.61 | SUNG_METASTASIS_STROMA_DN | MSigDB lists | SUNG_METASTASIS_STROMA_DN | 49 | 13 | 17377 | 2626 |
LYAR,PCNA,MCM5,ZNF367,HIPK2,CDCA5,PARP4,E2F1,HNRNPF,NUP153,PKMYT1,MCMBP,BYSL |
| 2.694e-02 | -3.61 | REACTOME_MAP_KINASE_ACTIVATION_IN_TLR_CASCADE | MSigDB lists | REACTOME_MAP_KINASE_ACTIVATION_IN_TLR_CASCADE | 49 | 13 | 17377 | 2626 |
PPP2CA,DUSP3,MAPKAPK3,TAB2,RPS6KA1,MEF2A,CREB1,ELK1,ATF2,MAPK14,MAPK1,MAP2K2,MAPK3 |
| 2.694e-02 | -3.61 | GO_RESPONSE_TO_GAMMA_RADIATION | MSigDB lists | GO_RESPONSE_TO_GAMMA_RADIATION | 49 | 13 | 17377 | 2626 |
BAK1,PRKDC,XRCC2,PRKAA1,H2AFX,TMEM109,PML,BCL2,BCL2L1,CHEK2,MEN1,ELK1,XRCC5 |
| 2.695e-02 | -3.61 | positive regulation of chromatin organization | biological process | GO:1905269 | 90 | 21 | 17256 | 2622 |
TGFB1,KAT2A,KMT2E,KAT7,MECP2,MIER1,WBP2,RTF1,BRCA1,CCNB1,TRIM28,MAPK3,PAF1,AKAP8,OGT,CTR9,BRD7,RUVBL2,CHTOP,SMAD4,DNMT1 |
| 2.700e-02 | -3.61 | mitochondrial proton-transporting ATP synthase complex | cellular component | GO:0005753 | 21 | 7 | 18223 | 2701 |
PPIF,ATP5IF1,ATP5F1A,ATP5F1B,ATP5MF,ATP5MC3,ATP5PF |
| 2.700e-02 | -3.61 | proteasome regulatory particle | cellular component | GO:0005838 | 21 | 7 | 18223 | 2701 |
PSMD2,PSMD1,PSMD9,PSMD8,PSMC1,PSMD3,PSMC4 |
| 2.701e-02 | -3.61 | GO_REGULATION_OF_INTRACELLULAR_SIGNAL_TRANSDUCTION | MSigDB lists | GO_REGULATION_OF_INTRACELLULAR_SIGNAL_TRANSDUCTION | 1601 | 269 | 17377 | 2626 |
TXN,TSC2,XIAP,UBE2I,SLC20A1,PPP1R16B,PARK7,CDK5,CALM2,NEK6,DNM2,TFG,SEH1L,MLST8,PLK3,PGAP2,PBK,EHMT1,MCL1,AURKB,RFC2,DOT1L,MAP3K4,RPS27A,AXIN1,ITGB1,OGT,ARRB2,TRAF5,PDCD4,HDAC2,SSRP1,HSPH1,RHOC,PRKAA1,VAV2,TRIO,GADD45G,NOTCH2,PSEN1,JMY,CFLAR,DDRGK1,FKBP1A,HDAC7,PIK3IP1,GNAI2,EEF1D,SOCS5,MAPKAPK3,MTA2,ZMYND11,PIP4K2C,BCLAF1,ADRB2,PTTG1IP,MAP2K2,RHOB,AKAP1,FAS,CAT,DUSP3,CSK,FAM83D,ARAP1,MAP3K5,CDK2,ZC3HAV1,ALS2,CDKN2A,RHOG,TP53RK,IVNS1ABP,TRIP10,UBR2,RAF1,MAGED1,RAC1,TPX2,RMI2,BCL2L1,SLC35B2,PRKACA,EPM2A,TERF2IP,CRKL,SHC1,SIAH1,SOCS6,MAVS,TP53BP2,GPD1L,CDK12,CPNE1,SHOC2,BRD4,RFC3,MAP4K4,TAOK1,VDAC2,CUL3,DNAJA1,SUPT16H,SOCS7,TAF2,PPP2CA,HINT1,HIPK2,STAT1,TICAM1,TRIM32,PPP5C,TMBIM4,ZFP91,FLOT1,AKT1S1,BLM,PIP5K1C,RPA2,PDCD10,PTEN,ARHGEF1,PTPN11,MAP3K14,PDPK1,TNFAIP3,NET1,FBXO9,ZP3,RHOT1,PDE3B,FADD,PRDX1,RPA1,TMEM127,GNA12,HGS,GPS2,PML,DDX5,PSAP,CD81,TAF6,IGBP1,FAF1,MIB2,NF1,CSNK2A1,NENF,S1PR2,BECN1,MAPK14,BIRC2,PRNP,RAP1A,C18orf32,CDC42,IL6ST,PIK3R2,NOC2L,SRI,AKR1B1,COPS8,TRIM8,MIOS,NCK1,EZR,UBE2V1,ARHGDIB,BRCA1,PRKRA,RHEB,OPTN,CHD3,SOCS4,ADAM9,ZNF268,STK11,CHEK2,CLU,PHB2,LAMTOR3,CIB1,RACGAP1,RGS2,CRLF3,MDFIC,BCL2,CYTH1,GBA,MAP4K3,KRAS,SYVN1,ARHGAP15,GNAS,TSC1,MBIP,NUP62,MYO9A,RBBP4,PRKAB1,ASH1L,CYLD,TRAF7,FOXM1,PLAGL2,RRAGC,IRF3,LYN,DUSP22,BCAP31,MEAF6,VAV1,RRN3,MDM2,KIF14,PIN1,PARL,F2R,HTRA2,DVL2,PPIF,ARHGAP17,TIMP2,BIRC3,MBD3,TAB2,PLEKHG4B,STK38,GADD45B,ARNTL,WDR59,CANT1,TMEM101,MAPK1,ABCA1,MIF,BCL2L12,MYO9B,PIP4K2A,RMI1,PTPN2,FGFR3,ZDHHC13,ARHGEF2,BRD7,STAT3,MYO5A,TGFB1,TELO2,RHOA,ATP2C1,MIER1,TOP3A,RFFL,ARHGEF12,MEN1,RHOT2,HSPA1B,MAPK3,MFN2,LEMD2,PDCD6,OSBPL8,PKD2,TAF12,ARHGAP23,HRAS,HIPK3 |
| 2.708e-02 | -3.61 | cell cortex | cellular component | GO:0005938 | 294 | 56 | 18223 | 2701 |
EXOC3,CYTIP,MAPRE1,AGTRAP,TRIP10,RHOC,SLC2A1,FLOT1,MYH9,ARFIP2,MYO9B,GLRX3,PSEN1,SAPCD2,RTKN,DST,TMEM250,CAPN2,ADD3,CDC42,SH3BP1,RALB,RIMS3,SEPT11,CORO1A,CLTB,GM2A,MICAL3,CFL1,DCTN1,SPTAN1,RHOBTB3,RHOA,SEPT9,MKLN1,AKT2,WDR1,EZR,SEPT8,WIPF1,CAPZA2,SEPT7,ANLN,RHOB,EPB41,TSC1,SEPT1,WAS,NSMF,EXOC4,PKD2,NRBP1,UNC13C,MYL12B,C2CD5,PARD3 |
| 2.710e-02 | -3.61 | GSE14415_FOXP3_KO_NATURAL_TREG_VS_TCONV_UP | MSigDB lists | GSE14415_FOXP3_KO_NATURAL_TREG_VS_TCONV_UP | 162 | 34 | 17377 | 2626 |
SLC12A7,PRPF38B,FAM208B,RPLP2,KRBA1,WDR13,CREBL2,TOP2B,CRLF3,RAPGEF6,CD3EAP,TTC3,EIF5,N4BP2,ARID4A,LDHB,DCAF6,EHMT1,BCLAF1,RAB3IP,ARID1A,LRRC1,ARHGAP15,RPL36,SH3BP5,PCM1,BRWD1,ACYP1,HNRNPH3,APPL2,ABCA1,PDCD4,GPATCH4,PRPF4B |
| 2.710e-02 | -3.61 | maintenance of protein localization in organelle | biological process | GO:0072595 | 39 | 11 | 17256 | 2622 |
CDK5,TXN,SP100,PML,RANGAP1,TOPORS,ANKRD13C,SUPT7L,PARK7,MORC3,KDELR1 |
| 2.710e-02 | -3.61 | mRNA stabilization | biological process | GO:0048255 | 39 | 11 | 17256 | 2622 |
SYNCRIP,DHX9,E2F1,AXIN2,CIRBP,TARDBP,YBX1,THRAP3,MAPK14,PABPC1,PAIP1 |
| 2.713e-02 | -3.61 | GSE17721_PAM3CSK4_VS_GADIQUIMOD_12H_BMDC_DN | MSigDB lists | GSE17721_PAM3CSK4_VS_GADIQUIMOD_12H_BMDC_DN | 196 | 40 | 17377 | 2626 |
PTMS,AGRN,SLC41A1,B4GALT5,RHOC,SCYL1,AP3M2,RRAGC,TBC1D13,CMTM6,KTN1,MAD2L2,ANKRD26,GSTK1,FGFR3,RCSD1,ANP32A,TNPO2,CENPM,CHTOP,TIPARP,NSUN4,MORC3,SAP30,CYTH1,TRAFD1,NASP,KLF6,RAB22A,SH3BP5,EIF4ENIF1,TRIM26,TAB2,PML,PPP1R11,CHMP4B,IGBP1,YWHAH,SMAD4,SMNDC1 |
| 2.714e-02 | -3.61 | S1P2 pathway | Pathway Interaction DB | s1p_s1p2_pathway | 24 | 9 | 2226 | 426 |
GNA12,RHOA,ELK1,S1PR2,MAPK1,GNAI2,MAPK14,RAC1,MAPK3 |
| 2.714e-02 | -3.61 | KIM_PTEN_TARGETS_DN | MSigDB lists | KIM_PTEN_TARGETS_DN | 5 | 3 | 17377 | 2626 |
PTEN,RBM4,ZNF574 |
| 2.714e-02 | -3.61 | TURJANSKI_MAPK11_TARGETS | MSigDB lists | TURJANSKI_MAPK11_TARGETS | 5 | 3 | 17377 | 2626 |
MEF2A,ELK1,ATF2 |
| 2.714e-02 | -3.61 | MYLLYKANGAS_AMPLIFICATION_HOT_SPOT_2 | MSigDB lists | MYLLYKANGAS_AMPLIFICATION_HOT_SPOT_2 | 5 | 3 | 17377 | 2626 |
KRAS,ERC1,ETV6 |
| 2.714e-02 | -3.61 | CALVET_IRINOTECAN_SENSITIVE_VS_REVERTED_UP | MSigDB lists | CALVET_IRINOTECAN_SENSITIVE_VS_REVERTED_UP | 5 | 3 | 17377 | 2626 |
PURA,RAC1,GMFB |
| 2.714e-02 | -3.61 | chr4q | MSigDB lists | chr4q | 5 | 3 | 17377 | 2626 |
CLCN3,CLTB,GAR1 |
| 2.714e-02 | -3.61 | KREPPEL_CD99_TARGETS_UP | MSigDB lists | KREPPEL_CD99_TARGETS_UP | 5 | 3 | 17377 | 2626 |
FBXO9,MCL1,KCMF1 |
| 2.717e-02 | -3.61 | PDE3B signalling | REACTOME pathways | R-HSA-165160 | 2 | 2 | 10287 | 1696 |
PDE3B,AKT2 |
| 2.717e-02 | -3.61 | Pyrophosphate hydrolysis | REACTOME pathways | R-HSA-71737 | 2 | 2 | 10287 | 1696 |
PPA1,PPA2 |
| 2.717e-02 | -3.61 | Insulin effects increased synthesis of Xylulose-5-Phosphate | REACTOME pathways | R-HSA-163754 | 2 | 2 | 10287 | 1696 |
TALDO1,TKT |
| 2.717e-02 | -3.61 | Mitotic Metaphase/Anaphase Transition | REACTOME pathways | R-HSA-68881 | 2 | 2 | 10287 | 1696 |
PLK1,FBXO5 |
| 2.721e-02 | -3.60 | - | gene3d domains | 1.10.720.30 | 24 | 8 | 8148 | 1295 |
SARNP,RAD18,SAFB,HNRNPUL2,PIAS2,SAFB2,SLTM,CCAR1 |
| 2.722e-02 | -3.60 | integral component of endoplasmic reticulum membrane | cellular component | GO:0030176 | 148 | 31 | 18223 | 2701 |
ANKLE2,ELOVL5,PIGT,HLA-E,TAP1,SLC35B2,SYVN1,ESYT1,SLC35B1,SPPL2B,BCAP31,HLA-A,RHBDD1,SPPL2A,DERL1,HLA-B,SEC61A1,RRBP1,SLC35B4,PIGG,ARL6IP1,SARAF,ZFYVE27,PKD2,ATF6,TAP2,SAMD8,CLN3,TECR,TMEM33,PREB |
| 2.724e-02 | -3.60 | protein localization to Golgi apparatus | biological process | GO:0034067 | 25 | 8 | 17256 | 2622 |
PACS1,GCC2,BICD2,RAB6A,ARL5B,ARL5A,CSNK1D,OPTN |
| 2.724e-02 | -3.60 | GSE3982_MAC_VS_BCELL_DN | MSigDB lists | GSE3982_MAC_VS_BCELL_DN | 179 | 37 | 17377 | 2626 |
MPHOSPH8,RAF1,MUM1,CHKB,DAZAP2,RUFY1,GIT2,PNO1,LRRC14,TERF2IP,HERC3,NRF1,ZNF473,MRPS27,RPL19,NAP1L4,MAML1,PPA1,EEF1D,PTPRK,NASP,DDX24,BIRC3,KIAA0040,PRKDC,TEX10,RNPS1,ZNF574,EZR,MAT2A,RPSA,HHEX,STK38,BAZ1B,MRFAP1L1,DEF6,TMEM131 |
| 2.724e-02 | -3.60 | GSE24210_TCONV_VS_TREG_DN | MSigDB lists | GSE24210_TCONV_VS_TREG_DN | 179 | 37 | 17377 | 2626 |
GALK1,GCLM,GLT8D1,MZT1,MTX3,GXYLT1,MRPS2,SEC61G,DAP,PPP1R15B,TOR3A,AKT1S1,EPHX2,PITHD1,RHBDD1,PRNP,CCNA2,EFCAB11,TOP1MT,TMBIM1,SPSB3,DRAM2,PHF10,TCTEX1D2,TSPAN31,MRPL12,ATXN1,NUSAP1,PRPF3,GAR1,ARNTL,KPNA2,GPI,SMPD4,CHEK2,MZT2B,ZMAT3 |
| 2.724e-02 | -3.60 | GSE17186_MEMORY_VS_NAIVE_BCELL_UP | MSigDB lists | GSE17186_MEMORY_VS_NAIVE_BCELL_UP | 179 | 37 | 17377 | 2626 |
SRM,TCF12,CCM2,ARID5A,SLC20A1,FAM8A1,BZW2,MAT2B,SIAH1,HDAC7,ATIC,BDH1,ARHGEF1,ZNF260,AXIN2,TTLL12,FRMD8,ANKRD9,TMEM9,KCNAB2,ABCC5,METTL1,TELO2,SELPLG,DENND4C,ESYT1,GALNT7,ICAM2,PPP2R5A,PDLIM1,FAM3C,LY75,GALNT10,XRCC4,ZNF146,BYSL,ESYT2 |
| 2.724e-02 | -3.60 | GSE2770_UNTREATED_VS_IL12_TREATED_ACT_CD4_TCELL_48H_DN | MSigDB lists | GSE2770_UNTREATED_VS_IL12_TREATED_ACT_CD4_TCELL_48H_DN | 179 | 37 | 17377 | 2626 |
UBE2D3,BCL2L12,DNAJC2,HABP4,TATDN3,NKRF,EBNA1BP2,BRIX1,NCAPG,PNO1,C14orf119,WRNIP1,TIMM23,UCHL5,UBA5,ANXA5,TNPO3,AQR,RPRD1B,CCAR1,DRAM2,VOPP1,MND1,MLEC,NASP,PSPC1,PBK,PCGF6,SLBP,SSR2,RAB1A,PCM1,PITPNA,CNOT6,WDR62,PGAM1,USF2 |
| 2.724e-02 | -3.60 | GSE13306_RA_VS_UNTREATED_TREG_UP | MSigDB lists | GSE13306_RA_VS_UNTREATED_TREG_UP | 179 | 37 | 17377 | 2626 |
SRM,HSPH1,URB2,USP39,PXMP2,EIF2AK4,GGA2,RSAD1,RRP36,TERF2IP,PA2G4,CLUAP1,HUWE1,SLC38A10,GLE1,ECD,TTC17,LPCAT1,MED22,LARS,ZBED5,WDHD1,DCTD,GSTCD,PTTG1IP,VKORC1,HAGH,GUF1,SFXN5,RAB2B,MAGED2,UTP20,PEX5,FAM3C,PREPL,LTA4H,PTDSS1 |
| 2.724e-02 | -3.60 | GSE36476_CTRL_VS_TSST_ACT_40H_MEMORY_CD4_TCELL_YOUNG_UP | MSigDB lists | GSE36476_CTRL_VS_TSST_ACT_40H_MEMORY_CD4_TCELL_YOUNG_UP | 179 | 37 | 17377 | 2626 |
UBL3,HECA,TSC22D3,TMEM41B,TMX4,DNAJB1,EZH1,DAZAP2,RLF,FAM8A1,CHD1,DNAJB9,MOAP1,ADD3,KLHL20,INPP5A,ZNF639,CRY2,PIK3IP1,TTC17,PLCL2,TIPARP,EEF1D,USP34,CYTH1,MAPRE2,TNFAIP3,TSPYL4,PBXIP1,ZMYM5,CIRBP,TMEM127,GOLGA4,GOLGA7,SMURF1,TOB1,ATMIN |
| 2.726e-02 | -3.60 | human chr1p34.2 | chromosome location | human chr1p34.2 | 68 | 13 | 26185 | 2809 |
PTPRF,HIVEP3,PPCS,MED8,PPT1,RIMS3,PPIE,SLC2A1,CTPS1,EBNA1BP2,YBX1,RLF,SMAP2 |
| 2.730e-02 | -3.60 | Cardiac Hypertrophic Response | WikiPathways | WP2795 | 57 | 15 | 5312 | 837 |
TGFB1,PDPK1,CALM2,PPP3CA,RAF1,HDAC7,AKT2,RAC1,NFATC2,MEF2A,MAP3K14,MAPK1,MAPK14,MAP2K2,MAPK3 |
| 2.734e-02 | -3.60 | ATRX (ATRX, chromatin remodeler) | protein interactions | 546 | 65 | 17 | 17029 | 2761 |
WDR1,PRKDC,SUMO2,DDX20,EIF2AK1,BLM,TRIM28,RPA1,XRCC5,SUPT16H,NEK1,MFAP1,PML,H2AFY,H3F3A,LUC7L2,SSRP1 |
| 2.734e-02 | -3.60 | RPS6KA5 (ribosomal protein S6 kinase A5) | protein interactions | 9252 | 65 | 17 | 17029 | 2761 |
ERH,HMGN1,PDLIM1,STAT1,SMARCA4,YWHAZ,MDFIC,STK11,AKT1S1,RNF19A,CREB1,ATF2,MAPK1,STAT3,MAPK14,APP,RPA1 |
| 2.734e-02 | -3.60 | GLI1 (GLI family zinc finger 1) | protein interactions | 2735 | 65 | 17 | 17029 | 2761 |
USP7,SMAD2,PHB2,VHL,PRKAA1,FEM1B,SMARCA4,CAPZA2,FXR1,PRKACA,SMAD4,USP21,GCC1,EEF1D,HDAC2,NUMB,ZMYM3 |
| 2.739e-02 | -3.60 | positive regulation of establishment of protein localization to mitochondrion | biological process | GO:1903749 | 64 | 16 | 17256 | 2622 |
UBE2D3,HUWE1,DYNLL1,PRKAA1,TFDP1,E2F1,PPP3R1,BCL2,YWHAZ,ATG13,TP53BP2,TFDP2,YWHAH,HTRA2,SH3GLB1,USP36 |
| 2.739e-02 | -3.60 | AAA | smart domains | SM00382 | 135 | 28 | 9493 | 1367 |
NTPCR,RFC3,ABCA3,CHTF18,ABCC10,ABCF2,TAP1,ABCB10,CDC6,ORC1,ATP5F1B,RFC2,ABCF1,WRNIP1,PSMC4,ATAD2,NVL,NSF,TAP2,ABCD1,VPS4A,RUVBL2,ABCA1,PSMC1,LONP2,RAD51D,ABCC1,ABCC5 |
| 2.742e-02 | -3.60 | RRCCGTTA_UNKNOWN | MSigDB lists | RRCCGTTA_UNKNOWN | 80 | 19 | 17377 | 2626 |
EWSR1,ILF3,CBLL1,FXR1,SRSF1,ADD3,GART,CDC27,UTP18,HNRNPR,BANF1,PHTF1,AP1M1,VCPIP1,TNPO3,FAM126A,TAGLN2,LUC7L2,CSTF1 |
| 2.742e-02 | -3.60 | GO_HYDROGEN_ION_TRANSMEMBRANE_TRANSPORTER_ACTIVITY | MSigDB lists | GO_HYDROGEN_ION_TRANSMEMBRANE_TRANSPORTER_ACTIVITY | 80 | 19 | 17377 | 2626 |
COX15,COX5B,UQCR10,ATP6V0A1,NDUFA4,COX4I1,ATP6V1B2,CYB5A,ATP6V0B,COX7A2L,COX8A,ATP6V0A2,COX5A,ATP6V0C,UQCRH,ATP6V1C1,ATP6V0D1,ATP6V0E1,ATP6V1G1 |
| 2.742e-02 | -3.60 | GO_CYSTEINE_TYPE_ENDOPEPTIDASE_ACTIVITY | MSigDB lists | GO_CYSTEINE_TYPE_ENDOPEPTIDASE_ACTIVITY | 80 | 19 | 17377 | 2626 |
USP7,CASP6,USP10,PEF1,CFLAR,USP5,ATG4A,CAPN2,PDCD6,CTSS,CAPN7,SRI,USP20,USP11,SENP1,ESPL1,CAPN1,USP34,USP13 |
| 2.743e-02 | -3.60 | Myh10 (myosin, heavy polypeptide 10, non-muscle) | protein interactions | 77579 | 141 | 32 | 17029 | 2761 |
CORO7,PPP1R12A,LUZP1,PHB2,POC1A,ACTR3,FLOT1,MYH9,SLC4A2,LYN,GNB2,CD59,ARPC5,CAPZA1,AP2B1,ECD,CLTB,GNAI2,CFL1,MYO5A,SPTAN1,PGS1,CAPZA2,DAPK3,INF2,PCM1,NAP1L1,GRIPAP1,CORO1C,MYO18A,LAMTOR4,NUMB |
| 2.743e-02 | -3.60 | PPARG (peroxisome proliferator activated receptor gamma) | protein interactions | 5468 | 141 | 32 | 17029 | 2761 |
USP7,NCOR2,ZNF496,MIF4GD,KAT2A,PHB2,FLYWCH2,MECP2,PRKAA1,GADD45G,SMARCA4,EDF1,MPG,PRMT2,UBE2I,KIF11,APP,XRCC5,RXRB,CDK5,RB1,MDM2,STAT6,PIN1,JAZF1,GADD45B,STAT1,PML,ANP32A,NCOA1,MAPK1,NCOA2 |
| 2.745e-02 | -3.60 | MYO18A (myosin XVIIIA) | protein interactions | 399687 | 162 | 36 | 17029 | 2761 |
PPP1R12A,LUZP1,ACTR3,DCTN2,MYH9,RPL15,SMARCA4,CSNK1A1,SEC16A,MYL6B,DDRGK1,DST,UTP25,CAPZA1,YIF1B,CLTB,MICAL3,CFL1,MYO5A,SPTAN1,PPP1R18,WDR1,ATXN1,RANGAP1,CAPZA2,PLEC,ANLN,PATL1,PICALM,DAPK3,INF2,SEPT1,CORO1C,ACTB,HMGB2,CDK2 |
| 2.745e-02 | -3.60 | CEP63 (centrosomal protein 63) | protein interactions | 80254 | 110 | 26 | 17029 | 2761 |
NCOR2,FGFR1OP,ZCCHC10,LUZP1,CCDC138,FOPNL,ARFIP2,HAUS4,MACF1,HAUS8,DST,MBIP,SMC3,PCM1,CCDC14,KIF14,PPP4R1,CEP55,TANK,EXOC4,TXLNA,ECD,SNRNP70,SMARCE1,SPTAN1,NXT2 |
| 2.748e-02 | -3.59 | FULCHER_INFLAMMATORY_RESPONSE_LECTIN_VS_LPS_DN | MSigDB lists | FULCHER_INFLAMMATORY_RESPONSE_LECTIN_VS_LPS_DN | 419 | 78 | 17377 | 2626 |
ZNF207,MAX,ATXN3,TXN,CAST,AP1B1,LYN,RPAIN,MXD1,HNRNPA2B1,UBXN2A,SP100,RAD23B,FNIP2,PLCL2,PDIA6,TIPARP,TRIM14,ABCC5,UBQLN4,KLF10,PFKFB3,NLN,DCLRE1C,RHBDF2,PLEKHF2,WDR11,RBM47,GADD45B,RBMS1,SCARB1,SLC22A23,REEP4,LTA4H,CHPT1,SMURF1,PRPF4B,SLC12A7,DDX58,SEPHS2,CASP6,B4GALT5,B4GALT1,CDK13,NOTCH2,GGA2,DOCK11,PITHD1,HAUS2,PDXDC1,RHBDD1,APOPT1,GNS,RB1,ADD3,SNX18,ZNRF2,H2AFY,AFF1,CITED2,LDLRAD3,LPCAT1,PPA1,SNX2,SUGP2,KCNQ1,LY6E,KLF6,PATL1,POLR2A,FAS,SCARB2,PCM1,NUP62,RUFY3,PARP10,USF2,IFI16 |
| 2.754e-02 | -3.59 | oligodendroglioma | COSMIC cancer mutations | oligodendroglioma | 21 | 7 | 17385 | 2587 |
CDKN2C,KRAS,NOTCH2,PTEN,CIC,CDKN2A,FUBP1 |
| 2.754e-02 | -3.59 | Merkel_cell_carcinoma | COSMIC cancer mutations | Merkel_cell_carcinoma | 21 | 7 | 17385 | 2587 |
RB1,KRAS,NRAS,PTEN,HRAS,AXIN1,CDKN2A |
| 2.754e-02 | -3.59 | vulva-carcinoma-squamous_cell_carcinoma | COSMIC cancer mutations | vulva-carcinoma-squamous_cell_carcinoma | 21 | 7 | 17385 | 2587 |
FGFR3,KRAS,NRAS,PTEN,SF3B1,HRAS,CDKN2A |
| 2.754e-02 | -3.59 | salivary_gland-carcinoma-mucoepidermoid_carcinoma | COSMIC cancer mutations | salivary_gland-carcinoma-mucoepidermoid_carcinoma | 21 | 7 | 17385 | 2587 |
KRAS,STK11,NRAS,PTEN,HRAS,SMAD4,CDKN2A |
| 2.754e-02 | -3.59 | testis-germ_cell_tumour | COSMIC cancer mutations | testis-germ_cell_tumour | 21 | 7 | 17385 | 2587 |
ANKLE1,KRAS,NRAS,PSMA8,HRAS,XRCC2,CHAF1A |
| 2.755e-02 | -3.59 | DNA replication, synthesis of RNA primer | biological process | GO:0006269 | 5 | 3 | 17256 | 2622 |
PRIM2,HELB,PRIM1 |
| 2.755e-02 | -3.59 | maintenance of DNA methylation | biological process | GO:0010216 | 5 | 3 | 17256 | 2622 |
USP7,DNMT1,UHRF2 |
| 2.755e-02 | -3.59 | protein localization to cell cortex | biological process | GO:0072697 | 5 | 3 | 17256 | 2622 |
EZR,ANLN,RTKN |
| 2.755e-02 | -3.59 | dephosphorylation of RNA polymerase II C-terminal domain | biological process | GO:0070940 | 5 | 3 | 17256 | 2622 |
CTDP1,RPRD1A,RPRD1B |
| 2.755e-02 | -3.59 | positive regulation of attachment of spindle microtubules to kinetochore | biological process | GO:0051987 | 5 | 3 | 17256 | 2622 |
SIRT2,CCNB1,BECN1 |
| 2.755e-02 | -3.59 | metaphase/anaphase transition of cell cycle | biological process | GO:0044784 | 5 | 3 | 17256 | 2622 |
CDC23,CDC27,TACC3 |
| 2.755e-02 | -3.59 | carbon catabolite activation of transcription | biological process | GO:0045991 | 5 | 3 | 17256 | 2622 |
USF1,NCOA1,USF2 |
| 2.755e-02 | -3.59 | positive regulation of clathrin-dependent endocytosis | biological process | GO:2000370 | 5 | 3 | 17256 | 2622 |
SCYL2,PICALM,DNM2 |
| 2.755e-02 | -3.59 | CRD-mediated mRNA stabilization | biological process | GO:0070934 | 5 | 3 | 17256 | 2622 |
YBX1,SYNCRIP,DHX9 |
| 2.755e-02 | -3.59 | spliceosomal conformational changes to generate catalytic conformation | biological process | GO:0000393 | 5 | 3 | 17256 | 2622 |
XAB2,PRPF18,PRPF19 |
| 2.755e-02 | -3.59 | regulation of chromosome condensation | biological process | GO:0060623 | 5 | 3 | 17256 | 2622 |
H3F3A,CCNB1,MCPH1 |
| 2.755e-02 | -3.59 | carbon catabolite regulation of transcription | biological process | GO:0045990 | 5 | 3 | 17256 | 2622 |
USF1,NCOA1,USF2 |
| 2.755e-02 | -3.59 | histone H3-K9 trimethylation | biological process | GO:0036124 | 5 | 3 | 17256 | 2622 |
BEND3,SUV39H2,ARID4A |
| 2.755e-02 | -3.59 | regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway | biological process | GO:0070432 | 5 | 3 | 17256 | 2622 |
ERBIN,TNFAIP3,HSPA1B |
| 2.755e-02 | -3.59 | neural plate regionalization | biological process | GO:0060897 | 5 | 3 | 17256 | 2622 |
CELSR2,AXIN1,SSBP3 |
| 2.755e-02 | -3.59 | protein polyufmylation | biological process | GO:1990564 | 5 | 3 | 17256 | 2622 |
UBA5,UFC1,DDRGK1 |
| 2.755e-02 | -3.59 | regulation of interferon-beta secretion | biological process | GO:0035547 | 5 | 3 | 17256 | 2622 |
DDX58,MAVS,DHX9 |
| 2.755e-02 | -3.59 | parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization | biological process | GO:0061734 | 5 | 3 | 17256 | 2622 |
SMURF1,OPTN,MFN2 |
| 2.755e-02 | -3.59 | ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway | biological process | GO:0090611 | 5 | 3 | 17256 | 2622 |
CHMP4B,PDCD6IP,VPS4A |
| 2.755e-02 | -3.59 | response to camptothecin | biological process | GO:1901563 | 5 | 3 | 17256 | 2622 |
BLM,SPIDR,PRKAA1 |
| 2.755e-02 | -3.59 | endoplasmic reticulum localization | biological process | GO:0051643 | 5 | 3 | 17256 | 2622 |
ESYT1,MYO5A,ESYT2 |
| 2.755e-02 | -3.59 | metaphase/anaphase transition of mitotic cell cycle | biological process | GO:0007091 | 5 | 3 | 17256 | 2622 |
CDC23,CDC27,TACC3 |
| 2.755e-02 | -3.59 | protein K69-linked ufmylation | biological process | GO:1990592 | 5 | 3 | 17256 | 2622 |
UBA5,UFC1,DDRGK1 |
| 2.755e-02 | -3.59 | maintenance of DNA repeat elements | biological process | GO:0043570 | 5 | 3 | 17256 | 2622 |
MSH6,MSH2,AXIN2 |
| 2.755e-02 | -3.59 | negative regulation of fat cell proliferation | biological process | GO:0070345 | 5 | 3 | 17256 | 2622 |
TFDP1,E2F1,E2F3 |
| 2.756e-02 | -3.59 | V$AP2_Q6 | MSigDB lists | V$AP2_Q6 | 248 | 49 | 17377 | 2626 |
ANKRD27,DNMT3A,MAPRE1,GGNBP2,PLXNC1,FAM129A,PLAGL2,SLC25A12,CTCF,USP48,POFUT1,CDC73,NRF1,KDM2A,RAB35,RRBP1,PPP6C,GLTP,BCL2,MAST2,CYB5R1,ECD,ST8SIA2,PABPC1,TERF2,EBAG9,RBM15B,SP3,C16orf72,MTA2,KAT7,LYRM1,LDB1,E2F3,RAB3IP,ARID1A,CADM1,ARPC1A,MBD3,RAB22A,TRIM28,HMGN2,UBTF,MAPK6,DDX5,ACTB,GALNT10,FAF1,ATXN7L2 |
| 2.757e-02 | -3.59 | DNAJ_2 | prosite domains | PS50076 | 48 | 12 | 12060 | 1670 |
DNAJC2,DNAJC10,DNAJC8,DNAJC5,DNAJB2,DNAJC17,DNAJC24,DNAJC9,DNAJA1,DNAJB1,DNAJC30,DNAJB9 |
| 2.760e-02 | -3.59 | GSE40274_CTRL_VS_IRF4_TRANSDUCED_ACTIVATED_CD4_TCELL_UP | MSigDB lists | GSE40274_CTRL_VS_IRF4_TRANSDUCED_ACTIVATED_CD4_TCELL_UP | 151 | 32 | 17377 | 2626 |
GOLPH3L,HNRNPUL2,CREBL2,TMEM165,POFUT1,NDUFS7,CTSS,ARL6IP1,SLC27A4,MRPL11,S100A6,LYPLA2,PDLIM2,PPP1R9B,MLEC,TCTEX1D2,TSTA3,WDR18,LRP5,EDEM2,TRIM28,UBTF,HHEX,PSAP,SCARB1,YY1,COPS6,CD81,AP2S1,RAB3IL1,EGLN1,SSRP1 |
| 2.760e-02 | -3.59 | HSF2 (heat shock transcription factor 2) | protein interactions | 3298 | 46 | 13 | 17029 | 2761 |
ANKLE2,HSPBP1,CDC27,SUMO2,CUL3,ASAH1,NUP62,UBE2I,CHTOP,WDR5,NCAPG,GM2A,IMPA2 |
| 2.760e-02 | -3.59 | CDV3 (CDV3 homolog) | protein interactions | 55573 | 46 | 13 | 17029 | 2761 |
SUGP1,CHMP2A,EWSR1,PPP1R12A,NDUFA2,NDUFAF2,RRBP1,PIAS2,NAA50,NSFL1C,RBM3,NDUFA7,PSMD9 |
| 2.760e-02 | -3.59 | ZNF232 (zinc finger protein 232) | protein interactions | 7775 | 46 | 13 | 17029 | 2761 |
ZBTB10,ZNF496,TK1,ZNF445,ZKSCAN1,TRIO,PPCDC,PPWD1,USP48,YY1,GTF2H2,PPP2R2D,ZNF174 |
| 2.760e-02 | -3.59 | DYNC1LI1 (dynein cytoplasmic 1 light intermediate chain 1) | protein interactions | 51143 | 46 | 13 | 17029 | 2761 |
PSMD8,DYNLL1,RAB4A,TKT,CUL3,RANGAP1,BICD2,USP48,NUP85,DYNC1LI2,ZFR,DCTN1,CDC5L |
| 2.760e-02 | -3.59 | NEK2 (NIMA related kinase 2) | protein interactions | 4751 | 46 | 13 | 17029 | 2761 |
IMMT,CDC16,CDC27,PPP1R2,ODF2,C16orf87,DTD1,CDC23,EDRF1,SMURF1,MAPK1,ANAPC4,DCTN1 |
| 2.760e-02 | -3.59 | XRCC4 (X-ray repair cross complementing 4) | protein interactions | 7518 | 46 | 13 | 17029 | 2761 |
FYTTD1,USP7,AHNAK,CWC27,CHD3,PRKDC,CSNK2A1,DNAJC9,DDX5,RNF135,XRCC4,SINHCAF,XRCC5 |
| 2.760e-02 | -3.59 | DUSP21 (dual specificity phosphatase 21) | protein interactions | 63904 | 46 | 13 | 17029 | 2761 |
PDCD6,MTX3,TIMMDC1,ARF5,MBLAC2,NDUFA11,PGRMC1,IMPDH1,COX4I1,GORASP2,TOMM40,RGS2,APP |
| 2.760e-02 | -3.59 | IQCF1 (IQ motif containing F1) | protein interactions | 132141 | 46 | 13 | 17029 | 2761 |
PAXX,FAM118B,INTS1,AP3M2,ABCD1,PACS1,EHD4,FAM208A,MZT2B,SNX14,MTR,TYW1B,DDRGK1 |
| 2.760e-02 | -3.59 | GBA (glucosylceramidase beta) | protein interactions | 2629 | 46 | 13 | 17029 | 2761 |
RAB21,RAB14,HSPA4,SCAMP3,ZCCHC8,ZFP91,ZMYND11,PSAP,ESYT1,ATP5PF,CCT8,PCBP2,RDH11 |
| 2.760e-02 | -3.59 | NFYC (nuclear transcription factor Y subunit gamma) | protein interactions | 4802 | 46 | 13 | 17029 | 2761 |
DST,SMAD2,SNX2,ARID2,CIC,CORO1C,USF3,NFATC2,ATF6,TAF12,CDK2,TAF6,ADNP2 |
| 2.760e-02 | -3.59 | NANS (N-acetylneuraminate synthase) | protein interactions | 54187 | 46 | 13 | 17029 | 2761 |
PA2G4,RPLP2,ATG3,DDA1,RAD23B,TKT,ANXA5,SND1,GPI,PKM,PPA1,PRDX1,GLOD4 |
| 2.760e-02 | -3.59 | RTEL1 (regulator of telomere elongation helicase 1) | protein interactions | 51750 | 46 | 13 | 17029 | 2761 |
ANKLE2,RPA2,AATF,NCK1,LIMK1,VAV2,CUL3,CBWD1,SASS6,TUBB,SSSCA1,RPA1,XRCC5 |
| 2.766e-02 | -3.59 | central_nervous_system-brainstem-glioma-astrocytoma_Grade_III | COSMIC cancer mutations | central_nervous_system-brainstem-glioma-astrocytoma_Grade_III | 114 | 25 | 17385 | 2587 |
TSHZ1,PPAN,MAX,TMBIM4,SMU1,KRAS,MEF2D,BRCA1,TANC1,USP21,ZMYM3,CHAF1A,TET3,CDKN2C,HSPBP1,CDCA4,PTEN,LMBR1,GPATCH1,TAGLN2,H3F3A,B4GALT3,CDKN2A,ABCC1,RLIM |
| 2.766e-02 | -3.59 | liposarcoma | COSMIC cancer mutations | liposarcoma | 114 | 25 | 17385 | 2587 |
TCF12,EWSR1,NRAS,NF1,SF3B1,GNE,TMEM109,BMS1,KRAS,ODC1,PDXDC1,MAP3K4,GNAS,RB1,ASAP2,PTEN,NUP107,STK11,FUS,PTPDC1,MAML1,HRAS,CDKN2A,FAM83G,CCAR1 |
| 2.776e-02 | -3.58 | CDC25B (cell division cycle 25B) | protein interactions | 994 | 105 | 25 | 17029 | 2761 |
FOXM1,PHB2,NF1,FAM53C,DENND4C,CUL1,CSNK2A1,RAB3IP,CCNB1,MAPK14,USP21,CCDC28A,GIGYF1,EDC3,RTKN,CDK5,AFDN,ZBTB21,FAM110A,KIF13B,YWHAZ,CDC25B,CDK2,YWHAH,CDC5L |
| 2.777e-02 | -3.58 | establishment of protein localization to vacuole | biological process | GO:0072666 | 44 | 12 | 17256 | 2622 |
NAGPA,GCC2,SCARB2,LARS,HGS,TNFAIP3,RAB7A,VTI1A,VPS4A,CLU,SMURF1,VPS25 |
| 2.777e-02 | -3.58 | regulation of G0 to G1 transition | biological process | GO:0070316 | 44 | 12 | 17256 | 2622 |
MAX,SUZ12,EHMT1,TFDP1,PCGF6,E2F1,RRM2,BRCA1,RBBP4,TFDP2,RYBP,CBX3 |
| 2.778e-02 | -3.58 | organelle envelope lumen | cellular component | GO:0031970 | 87 | 20 | 18223 | 2701 |
TIMM8B,NDUFS1,CPOX,NLN,CHCHD2,CYCS,COA7,LYN,GFER,PARK7,APP,STOML2,CAT,TIMM13,TIMM23,TIMM29,MICU2,NDUFS5,TUBB,HTRA2 |
| 2.779e-02 | -3.58 | V$ELF1_Q6 | MSigDB lists | V$ELF1_Q6 | 225 | 45 | 17377 | 2626 |
CMAS,GOLPH3L,RAC1,XIAP,SLC39A13,AGPAT1,KLF13,CTCF,AKT1S1,DUSP22,RUFY1,XPR1,ANKRD28,VAV1,ADD3,RPL17,CNOT6L,MTPN,PABPC1,RNF5,RLIM,ACSL5,TGFB1,NIPAL3,PPP3CA,NASP,SNX2,ERF,NCK1,E2F3,LRRC8A,ARHGDIB,SUPT16H,PI4K2A,DERL1,WAS,TBC1D17,ELMO1,FAM110A,TFE3,STAT6,CTSA,WIPI2,ARRB2,CDKN2A |
| 2.782e-02 | -3.58 | WASHC3 (WASH complex subunit 3) | protein interactions | 51019 | 70 | 18 | 17029 | 2761 |
WASF2,GCC2,PBXIP1,RB1CC1,GGA1,POC1A,CAPZA2,BICD2,IKBIP,OPTN,PCM1,GOLGA4,GOLGA2,CEP55,TXLNA,NUP62,ATG13,LUC7L2 |
| 2.782e-02 | -3.58 | GSK3A (glycogen synthase kinase 3 alpha) | protein interactions | 2931 | 70 | 18 | 17029 | 2761 |
DEAF1,PPP1R2,KRBA1,FOXM1,PRKDC,RAE1,MCL1,EBNA1BP2,PPP3CB,BCL2L1,PRKACA,CREM,PRKD3,PSMD1,AXIN1,AXIN2,CREB1,LRSAM1 |
| 2.782e-02 | -3.58 | DLK1 (delta like non-canonical Notch ligand 1) | protein interactions | 8788 | 70 | 18 | 17029 | 2761 |
ANKRD27,ATP13A1,NUP188,MBLAC2,ADPGK,TFRC,ZNF696,LEMD2,GOLGA2,WDR44,INTS7,NCLN,ANKRD13C,UBE3B,CABLES2,OSTC,C2CD5,CABLES1 |
| 2.782e-02 | -3.58 | FGL1 (fibrinogen like 1) | protein interactions | 2267 | 70 | 18 | 17029 | 2761 |
ANKLE2,CMAS,MAPRE2,FAM172A,NSUN2,VKORC1,ZADH2,SLTM,LSG1,GOLM1,AFDN,TEDC2,NUCB1,UBA5,PPIL2,ARHGEF2,GTF2H2,NAA35 |
| 2.783e-02 | -3.58 | protein serine/threonine kinase activator activity | molecular function | GO:0043539 | 34 | 10 | 17224 | 2647 |
CALM2,TGFB1,TAOK1,DBF4,CAB39,CCNB1,DAZAP2,MAP2K2,ALS2,MLST8 |
| 2.783e-02 | -3.58 | Hsp70 protein binding | molecular function | GO:0030544 | 34 | 10 | 17224 | 2647 |
DNAJC2,DNAJC10,TSC1,DNAJC8,ST13,DNAJB2,NUP62,DNAJB1,DNAJA1,DNAJB9 |
| 2.788e-02 | -3.58 | PEX3 (peroxisomal biogenesis factor 3) | protein interactions | 8504 | 8 | 4 | 17029 | 2761 |
ABCD1,HNRNPR,DHX15,HNRNPF |
| 2.788e-02 | -3.58 | RWDD4 (RWD domain containing 4) | protein interactions | 201965 | 8 | 4 | 17029 | 2761 |
BRCA1,BTF3,ZNF330,KCTD17 |
| 2.788e-02 | -3.58 | LIN52 (lin-52 DREAM MuvB core complex component) | protein interactions | 91750 | 8 | 4 | 17029 | 2761 |
LIN9,RBBP4,MYBL1,MYBL2 |
| 2.788e-02 | -3.58 | SLF1 (SMC5-SMC6 complex localization factor 1) | protein interactions | 84250 | 8 | 4 | 17029 | 2761 |
SMC6,RAD18,SLF2,USP21 |
| 2.788e-02 | -3.58 | DCDC1 (doublecortin domain containing 1) | protein interactions | 341019 | 8 | 4 | 17029 | 2761 |
RAB8A,RAB3IP,NUDC,DCTN1 |
| 2.788e-02 | -3.58 | USP32P2 (ubiquitin specific peptidase 32 pseudogene 2) | protein interactions | 220594 | 8 | 4 | 17029 | 2761 |
CYLD,SEH1L,USP5,USP32 |
| 2.788e-02 | -3.58 | TRIM72 (tripartite motif containing 72) | protein interactions | 493829 | 8 | 4 | 17029 | 2761 |
MYH9,TCF12,TRIM32,UBE2I |
| 2.788e-02 | -3.58 | Lin54 (lin-54 homolog (C. elegans)) | protein interactions | 231506 | 8 | 4 | 17029 | 2761 |
LIN9,RBBP4,MYBL1,MYBL2 |
| 2.788e-02 | -3.58 | BTNL3 (butyrophilin like 3) | protein interactions | 10917 | 8 | 4 | 17029 | 2761 |
ACP2,SCARB1,CYP20A1,SLC25A51 |
| 2.788e-02 | -3.58 | Cenpq (centromere protein Q) | protein interactions | 83815 | 8 | 4 | 17029 | 2761 |
LETMD1,LTN1,BANF1,CENPU |
| 2.788e-02 | -3.58 | SPIN3 (spindlin family member 3) | protein interactions | 169981 | 8 | 4 | 17029 | 2761 |
SPINDOC,CYLD,ARRB2,PFDN4 |
| 2.788e-02 | -3.58 | INTS4P2 (integrator complex subunit 4 pseudogene 2) | protein interactions | 644619 | 8 | 4 | 17029 | 2761 |
NAT14,TOLLIP,ASPM,MRS2 |
| 2.788e-02 | -3.58 | PCSK7 (proprotein convertase subtilisin/kexin type 7) | protein interactions | 9159 | 8 | 4 | 17029 | 2761 |
CSDE1,PCSK7,SYNCRIP,PABPC1 |
| 2.788e-02 | -3.58 | PYROXD1 (pyridine nucleotide-disulphide oxidoreductase domain 1) | protein interactions | 79912 | 8 | 4 | 17029 | 2761 |
UPRT,DHX16,APP,ILF3 |
| 2.788e-02 | -3.58 | CGNL1 (cingulin like 1) | protein interactions | 84952 | 8 | 4 | 17029 | 2761 |
YWHAZ,TRAF7,NDE1,GRIPAP1 |
| 2.788e-02 | -3.58 | Terf1 (telomeric repeat binding factor 1) | protein interactions | 21749 | 8 | 4 | 17029 | 2761 |
TERF2IP,PRKDC,POT1,TERF2 |
| 2.788e-02 | -3.58 | HIST1H2BI (histone cluster 1 H2B family member i) | protein interactions | 8346 | 8 | 4 | 17029 | 2761 |
COX15,VDAC1,MCM2,SDHA |
| 2.788e-02 | -3.58 | ADARB2 (adenosine deaminase, RNA specific B2 (inactive)) | protein interactions | 105 | 8 | 4 | 17029 | 2761 |
KIF11,ANKHD1,PIK3R2,GPATCH4 |
| 2.788e-02 | -3.58 | Smc6 (structural maintenance of chromosomes 6) | protein interactions | 67241 | 8 | 4 | 17029 | 2761 |
SMC6,NSMCE4A,RAD18,NSMCE2 |
| 2.788e-02 | -3.58 | TOP1MT (DNA topoisomerase I mitochondrial) | protein interactions | 116447 | 8 | 4 | 17029 | 2761 |
TFG,CDK2,MCM5,NUP58 |
| 2.788e-02 | -3.58 | SERINC2 (serine incorporator 2) | protein interactions | 347735 | 8 | 4 | 17029 | 2761 |
ATP6V0A1,ATP6V0A2,ATP6V0D1,GPR89B |
| 2.788e-02 | -3.58 | RPSAP15 (ribosomal protein SA pseudogene 15) | protein interactions | 220885 | 8 | 4 | 17029 | 2761 |
CUL1,EWSR1,CAND1,CUL3 |
| 2.788e-02 | -3.58 | RAB38 (RAB38, member RAS oncogene family) | protein interactions | 23682 | 8 | 4 | 17029 | 2761 |
SMAD2,SMAD1,SMAD4,APP |
| 2.788e-02 | -3.58 | SFTA2 (surfactant associated 2) | protein interactions | 389376 | 8 | 4 | 17029 | 2761 |
CBWD1,CBWD2,OAF,NMD3 |
| 2.788e-02 | -3.58 | ZNF7 (zinc finger protein 7) | protein interactions | 7553 | 8 | 4 | 17029 | 2761 |
NIFK,DGCR8,MAPK6,MAPK3 |
| 2.788e-02 | -3.58 | Id2 (inhibitor of DNA binding 2) | protein interactions | 15902 | 8 | 4 | 17029 | 2761 |
TCF12,SYMPK,APOL2,TCF3 |
| 2.788e-02 | -3.58 | PLEKHM1 (pleckstrin homology and RUN domain containing M1) | protein interactions | 9842 | 8 | 4 | 17029 | 2761 |
MOB4,EIF2S2,MAPK6,GADD45G |
| 2.788e-02 | -3.58 | ZNF70 (zinc finger protein 70) | protein interactions | 7621 | 8 | 4 | 17029 | 2761 |
NIFK,ZFP64,DGCR8,ZC3H3 |
| 2.788e-02 | -3.58 | TEX33 (testis expressed 33) | protein interactions | 339669 | 8 | 4 | 17029 | 2761 |
ATE1,YWHAZ,UBR2,CARM1 |
| 2.788e-02 | -3.58 | VAMP5 (vesicle associated membrane protein 5) | protein interactions | 10791 | 8 | 4 | 17029 | 2761 |
STX16,SNAP29,SNAP23,LMNA |
| 2.788e-02 | -3.58 | HMGN3 (high mobility group nucleosomal binding domain 3) | protein interactions | 9324 | 8 | 4 | 17029 | 2761 |
TERF2IP,TERF1,TERF2,SRPK2 |
| 2.788e-02 | -3.58 | GPR107 (G protein-coupled receptor 107) | protein interactions | 57720 | 8 | 4 | 17029 | 2761 |
NEK7,REEP5,BIRC2,TMEM216 |
| 2.788e-02 | -3.58 | HIST1H2BF (histone cluster 1 H2B family member f) | protein interactions | 8343 | 8 | 4 | 17029 | 2761 |
COX15,VDAC1,MCM2,SDHA |
| 2.788e-02 | -3.58 | GNAL (G protein subunit alpha L) | protein interactions | 2774 | 8 | 4 | 17029 | 2761 |
GNAS,MAGED2,SPATA2,BABAM1 |
| 2.788e-02 | -3.58 | NUP62CL (nucleoporin 62 C-terminal like) | protein interactions | 54830 | 8 | 4 | 17029 | 2761 |
NUP58,APP,NUP54,OGT |
| 2.788e-02 | -3.58 | Cit (citron) | protein interactions | 12704 | 8 | 4 | 17029 | 2761 |
TTC3,PCM1,KIF14,PRKAA1 |
| 2.788e-02 | -3.58 | HSFX1 (heat shock transcription factor family, X-linked 1) | protein interactions | 100506164 | 8 | 4 | 17029 | 2761 |
FAM192A,ATXN1,CCDC57,IARS2 |
| 2.793e-02 | -3.58 | HIV Transcription Elongation | REACTOME pathways | R-HSA-167169 | 50 | 14 | 10287 | 1696 |
CTDP1,POLR2I,POLR2J,POLR2G,POLR2L,POLR2K,ELOA,POLR2D,TCEA1,GTF2H2,POLR2A,GTF2F1,SSRP1,SUPT16H |
| 2.793e-02 | -3.58 | Death Receptor Signalling | REACTOME pathways | R-HSA-73887 | 50 | 14 | 10287 | 1696 |
ADAM17,CYLD,TNFAIP3,BIRC3,TAB2,RPS27A,XIAP,SPPL2B,USP21,BIRC2,FADD,CFLAR,SPPL2A,FAS |
| 2.793e-02 | -3.58 | Tat-mediated elongation of the HIV-1 transcript | REACTOME pathways | R-HSA-167246 | 50 | 14 | 10287 | 1696 |
CTDP1,POLR2I,POLR2J,POLR2G,POLR2L,POLR2K,ELOA,POLR2D,TCEA1,GTF2H2,POLR2A,GTF2F1,SSRP1,SUPT16H |
| 2.793e-02 | -3.58 | Formation of HIV-1 elongation complex containing HIV-1 Tat | REACTOME pathways | R-HSA-167200 | 50 | 14 | 10287 | 1696 |
CTDP1,POLR2I,POLR2J,POLR2G,POLR2L,POLR2K,ELOA,POLR2D,TCEA1,GTF2H2,POLR2A,GTF2F1,SSRP1,SUPT16H |
| 2.794e-02 | -3.58 | oxidation-reduction process | biological process | GO:0055114 | 915 | 160 | 17256 | 2622 |
COX15,TXN,NDUFB6,KDM4A,UQCR10,ALKBH5,DNAJC24,GLUD1,GYG1,MAPK14,PARK7,ASPHD2,PCYOX1L,TET3,MTFR1L,IL6ST,CYB5RL,MECR,HADHB,AKR1B1,SUCLG2,NDUFB9,TECR,KCNAB2,AKT2,RIOX2,RRM2,FOXRED1,RPS27A,UEVLD,PRDX5,COX5A,DHTKD1,UQCRH,DHFR2,PFKP,NDUFV2,COX5B,PPP1R2,ADO,PRKAA1,RRM1,NDUFA4,COX4I1,CYCS,RSAD1,QSOX2,NDUFS7,NDUFS4,BDH1,CYC1,ACAD8,ALDH18A1,PHKG2,ALDH9A1,TSTA3,RB1CC1,NSDHL,NQO2,OXR1,MTFR2,ERO1A,RDH10,TYW1,VKORC1,PKM,KDM3A,CYB5A,RDH11,GNAS,SDHB,CAT,MTHFD2,COX7A2L,TYW5,MDH1,GPI,EGLN1,NDUFA5,MMACHC,UGP2,SUCLG1,NQO1,NDUFAF2,MDH2,TMX4,ADPGK,GLRX3,ZADH2,SDHA,FLAD1,DECR1,DUS4L,KDM2A,CS,CYB5R1,GPD1L,PDIA6,GPX4,KDM3B,HPDL,COQ10B,IDH3A,CPOX,CYP20A1,NARF,HTATIP2,NDUFA7,OGDH,NDUFB1,KDM1B,TAZ,POLG2,GFER,ALKBH6,DNAJC10,ALDH3B1,DUS3L,NDUFA11,NDUFS1,MECP2,TMX3,SLC25A12,JMJD6,SUMF1,SPR,SRXN1,FASTKD3,PPP1R3B,GSTK1,NDUFV1,NDUFA2,NDUFB4,CRAT,DUS2,ABCD1,NDUFS8,NDUFA3,RNLS,MICAL3,TMX1,LDHB,TXNL1,LDHA,TBRG4,ADSL,PRDX1,ECH1,PRDX3,ACOX1,COX8A,ACAT1,IMPDH1,NDUFS5,ACADM,IDH3B,PLOD3,PGAM1,HIGD2A,TYW1B |
| 2.794e-02 | -3.58 | GSE13485_DAY7_VS_DAY21_YF17D_VACCINE_PBMC_UP | MSigDB lists | GSE13485_DAY7_VS_DAY21_YF17D_VACCINE_PBMC_UP | 185 | 38 | 17377 | 2626 |
NCOR2,ZBTB10,CORO7,PARP12,SESTD1,RAC1,AGPAT1,AGPAT3,SNN,LYN,CAPN2,TNS3,ASAP2,SP100,SAR1A,AKAP8,ETV6,ZCCHC2,FNIP2,RYBP,KLF10,LAP3,USP42,UHRF1BP1,LY6E,ZDHHC3,ISG15,CHAF1A,HAUS8,MAN2A2,PWWP2B,SCARB2,PML,STAT1,PKD2,RGL1,SAT2,IPO4 |
| 2.794e-02 | -3.58 | GSE41867_NAIVE_VS_DAY6_LCMV_EFFECTOR_CD8_TCELL_UP | MSigDB lists | GSE41867_NAIVE_VS_DAY6_LCMV_EFFECTOR_CD8_TCELL_UP | 185 | 38 | 17377 | 2626 |
WASF2,PLXNC1,AGRN,PHRF1,PTTG1,CIB1,PXMP2,POMP,TWF2,GTF2F1,CFLAR,GNS,CLUAP1,ORAI1,SS18L1,TAP2,CNPY3,LPCAT1,ENPP4,CYFIP1,RBX1,PPP1R21,VDAC2,MAP4K3,ESYT1,PSMB9,STK17B,SH3GLB1,TFEB,NAP1L1,UBXN2B,NLRC5,PML,ACTB,TAF12,MYL12B,AP2S1,PDCD4 |
| 2.794e-02 | -3.58 | GSE6875_TCONV_VS_FOXP3_KO_TREG_UP | MSigDB lists | GSE6875_TCONV_VS_FOXP3_KO_TREG_UP | 185 | 38 | 17377 | 2626 |
ZNF296,SART1,TMUB1,NSMCE4A,GMFG,ADD1,CCM2,HEXB,ARF1,DOCK11,COMMD8,MAN1A1,ABHD16A,STRBP,ARPC5,CRAT,ZBTB22,CDC25B,SLC26A2,ZNF710,GPD1L,RHOA,FOXK1,RFXANK,EMP3,LRRC1,KRTCAP2,RPA1,KPNA4,DGCR8,STK38,FAM3C,DCAF11,AKNA,SMAD1,FAU,ESYT2,RHEBL1 |
| 2.794e-02 | -3.58 | GSE17721_0.5H_VS_4H_CPG_BMDC_DN | MSigDB lists | GSE17721_0.5H_VS_4H_CPG_BMDC_DN | 185 | 38 | 17377 | 2626 |
PKP4,FAM53C,PPP1R15B,TOR3A,TAP1,PLAGL2,TBC1D13,B4GALT4,REPS1,SLC25A37,PHC2,TANK,AFF1,RNF19A,CREB1,TFG,SGCB,FDFT1,ENPP4,MOB4,ADAM17,BIRC3,ELL2,LAP3,MKI67,RFFL,TOR1AIP2,RAB3IP,ASB13,RAB1A,RDH11,TRIM26,ETS2,RBL1,MAFK,ZNF436,GALNT10,ABCA1 |
| 2.794e-02 | -3.58 | GSE22886_TH1_VS_TH2_12H_ACT_UP | MSigDB lists | GSE22886_TH1_VS_TH2_12H_ACT_UP | 185 | 38 | 17377 | 2626 |
GGNBP2,MAGEH1,TMEM184B,RPS6KA1,ANK3,FLOT1,IP6K2,ATP6V1B2,ASXL2,PNO1,PIP5K1C,GOLM1,NRF1,EXOSC7,PTEN,DPYSL2,PIN1,SSBP3,FUT8,DCP1A,RPAP1,ANXA5,ARHGEF2,CDC25B,RBM15B,BICD2,LY6E,CYFIP2,APPL1,TRIM26,KPNA1,MID1IP1,STX18,PQBP1,NCLN,HRAS,NUMB,TMEM131 |
| 2.794e-02 | -3.58 | GGGACCA,MIR-133A,MIR-133B | MSigDB lists | GGGACCA,MIR-133A,MIR-133B | 185 | 38 | 17377 | 2626 |
RAB14,ABCA3,ST13,ZDHHC8,ZFP91,YTHDF3,ARFIP2,MYH9,CHKB,BCL2L1,FKBP2,RAPGEF6,DLG5,CDC42,THADA,IL6ST,PPP1R12C,DNM2,ARHGEF2,TAGLN2,SENP1,PABPC1,SOCS5,EIF5A,PLK3,PPP1R9B,KIAA0040,BAZ2A,PFKFB3,SREK1,ZMYM3,OSBPL8,USP32,APPL2,WIPI2,RBBP4,B4GALT2,NIPA1 |
| 2.794e-02 | -3.58 | GSE14308_TH2_VS_NATURAL_TREG_DN | MSigDB lists | GSE14308_TH2_VS_NATURAL_TREG_DN | 185 | 38 | 17377 | 2626 |
USP7,COPA,PTTG1,DCTN2,UCK1,SMARCA4,TOP2B,ETS1,TTF1,SNAPC4,EDC3,DDRGK1,ASAP2,RCSD1,HADHB,TAP2,CREB1,NCOA2,HTRA2,ANKLE2,MKLN1,PPP1R21,GNG7,TUBGCP5,CBFA2T2,ARSK,BSDC1,IDE,OSBPL8,GADD45B,USP32,PDXK,CLN3,BRD9,ACSF2,TSPAN5,ZNF598,ATMIN |
| 2.794e-02 | -3.58 | GSE11961_GERMINAL_CENTER_BCELL_DAY7_VS_GERMINAL_CENTER_BCELL_DAY40_UP | MSigDB lists | GSE11961_GERMINAL_CENTER_BCELL_DAY7_VS_GERMINAL_CENTER_BCELL_DAY40_UP | 185 | 38 | 17377 | 2626 |
TXN,LUZP1,CKLF,DAP,GYG1,DUSP22,PSMD9,MXD1,MDM2,PCNA,PSMD1,DUT,RRBP1,YBX1,TAGLN2,ARL5A,S100A6,KCNAB2,TACC3,PDCL3,VOPP1,MLEC,LONRF3,TNFAIP3,PBK,WDHD1,SREK1,CDCA2,VDAC1,BORA,RAD54B,PRIM1,PDCD6,GALNT2,CERS6,PTER,MAPK6,LRP8 |
| 2.798e-02 | -3.58 | GO_NEGATIVE_REGULATION_OF_INTRACELLULAR_TRANSPORT | MSigDB lists | GO_NEGATIVE_REGULATION_OF_INTRACELLULAR_TRANSPORT | 140 | 30 | 17377 | 2626 |
TGFB1,CYLD,TXN,NF1,GOPC,RAB23,RANGAP1,SOX4,SLC25A5,PARK7,AKAP1,FKBP1A,CDK5,CALM2,RAP1A,KEAP1,SP100,TONSL,CSK,SRI,OGT,AXIN2,FAM89B,BCL2,PKD2,MDFIC,NUP153,PARP10,FAF1,SVIP |
| 2.799e-02 | -3.58 | GO_PROTEIN_PHOSPHORYLATION | MSigDB lists | GO_PROTEIN_PHOSPHORYLATION | 920 | 160 | 17377 | 2626 |
CCNC,FGFR1OP,ADAM10,NF1,SNX15,CUL1,CSNK2A1,CCNB1,MAPK14,RBM4,EEF2K,CDK5,CALM2,ABL2,PSMD1,NEK6,FNIP2,CDC25B,MAST2,FGFR1OP2,CDC37,SRPK2,PLK3,PLK1,NRAS,RBX1,AKT2,PBK,TLK1,GMFB,AURKB,IL12RB1,PRKRA,STK17B,MAP3K4,MKNK1,SMAD2,RPS27A,PSMD8,LIMK1,AXIN1,BAZ1B,CAB39,STK11,CHEK2,RNASEL,ROCK1,SMAD1,PSMC1,GMFG,CLSPN,PRKAA1,TRIO,LAMTOR3,MEF2A,ADCK5,CDK13,PPP3CB,EIF2AK4,PSMD9,PPP4R1,DAPK1,BCL2,MDFIC,MAML1,PHKG2,CSNK1G3,MORC3,MAPKAPK3,RB1CC1,PSMA1,KRAS,MAP4K3,EIF2AK1,EIF2A,MAP2K2,PSMB3,DAPK3,PSMC4,MASTL,CSK,CSNK1G1,MAP3K5,CDK2,NRBP1,PRKAB1,TP53RK,RAF1,RPS6KA1,LYN,PRKACA,CPNE3,APP,CRKL,PRKD3,PDK2,PSMA6,SHC1,F2R,CDK12,ABI1,SCYL3,ULK3,PSMA8,TAOK1,MAP4K4,CUL3,PSMB7,PKMYT1,PSMB9,TRIM28,ERC1,JAK1,CLK3,TAB2,HIPK2,PSMD3,FASTK,STK38,PPP5C,MAPK1,CSNK1D,PRPF4B,SH2D3A,CCM2,SCYL1,BRAP,CDK11B,CSNK1A1,SCYL2,CCNK,FASTKD3,PSMD2,FGFR3,MAP3K14,CREB1,GTF2H2,CAMK2G,SPTAN1,TGFB1,PDPK1,CSNK1G2,NEK7,PRKDC,PRKAR1B,ILF3,TBRG4,MEN1,MARK2,CDK11A,MAPK3,NEK1,BIRC5,GPS2,MAPK6,KBTBD7,PML,RPS6KC1,HIPK3,HRAS |
| 2.805e-02 | -3.57 | ABC transporter disorders | REACTOME pathways | R-HSA-5619084 | 69 | 18 | 10287 | 1696 |
PSMA8,ERLIN1,PSMB7,PSMA1,PSMB9,PSMD9,PSMB3,PSMC4,DERL1,PSMD2,PSMA6,PSMD1,RPS27A,PSMD3,PSMD8,SEL1L,PSMC1,RNF5 |
| 2.806e-02 | -3.57 | neuron death | biological process | GO:0070997 | 49 | 13 | 17256 | 2622 |
CDK5,RB1,MAX,PIGT,SIAH1,AKT2,OXR1,BCL2,BCL2L1,PSEN1,APP,USP53,FADD |
| 2.806e-02 | -3.57 | glycosyl compound biosynthetic process | biological process | GO:1901659 | 49 | 13 | 17256 | 2622 |
ADA2,TK1,GUK1,DCK,AMD1,TYW5,UCK2,CTPS1,UPRT,IMPDH1,UCK1,DHFR2,PDCL3 |
| 2.806e-02 | -3.57 | establishment or maintenance of bipolar cell polarity | biological process | GO:0061245 | 49 | 13 | 17256 | 2622 |
DLG5,PDCD6IP,RHOA,CLIC4,CDC42,SH3BP1,WDR1,EZR,ERBIN,MYO9A,MARK2,ARF4,PARD3 |
| 2.806e-02 | -3.57 | establishment or maintenance of apical/basal cell polarity | biological process | GO:0035088 | 49 | 13 | 17256 | 2622 |
DLG5,PDCD6IP,RHOA,CLIC4,CDC42,SH3BP1,WDR1,EZR,ERBIN,MYO9A,MARK2,ARF4,PARD3 |
| 2.807e-02 | -3.57 | secretion by cell | biological process | GO:0032940 | 983 | 171 | 17256 | 2622 |
ADA2,RAB14,ADAM10,NF1,HEXB,UBE2Q1,NHLRC3,GYG1,MAPK14,CMTM6,KCMF1,PARK7,PCYOX1L,CDK5,PA2G4,RAB8A,PSMD1,RAP1A,AP1M1,TXLNA,KCNAB2,NRAS,ARHGAP45,CYSTM1,PPFIA3,RAB5B,SMAD2,AGPAT2,TMED10,MIA2,CAB39,ATP6V0C,CLU,DVL1,ROCK1,CAPN1,SVIP,DNAJC5,GMFG,NKD2,LAMTOR3,ASAH1,B4GALT1,CDK13,MAN2B1,RAB6A,PPP3CB,PSEN1,COPG2,TMEM179B,GNS,CD59,ARPC5,VMP1,RIMS3,OSTF1,MVP,LPCAT1,SYTL3,PREB,NAGPA,CYFIP1,FTL,CREG1,WDR1,C1orf35,PKM,ARMC8,CCT8,PI4K2A,XRCC5,CAND1,MAGED2,CAT,NSF,SNAP23,ACLY,EXOC4,CTSA,GPI,UNC13C,EXOC3,RHOG,CKLF,RAB11B,RAF1,DYNLL1,RAC1,OLA1,NIT2,LYN,CPNE3,APP,APLP2,BRPF3,BRI3,CORO1A,CYB5R1,APOOL,TMBIM1,GM2A,CHP1,CPNE1,ENPP4,CCT2,ARHGAP17,TIMP2,PPT1,RAB7A,PPIE,PSMB7,ATP6V0A1,RAB1A,TOLLIP,ALDH3B1,DSN1,DDOST,SURF4,RAB24,PSMD3,SEL1L,CANT1,PDXK,MAPK1,LTA4H,CHID1,ABCA1,TUBB,MIF,MECP2,MANBA,PDAP1,HABP4,SRGN,VPS45,TMX3,BTN3A1,RAB11A,PIP5K1C,FERMT3,PSMD2,CTSS,HUWE1,ANXA5,TAGLN2,CNN2,CAMK2G,MYO5A,MICAL3,SPTAN1,TGFB1,MLEC,RHOA,FAM49B,SCFD2,HEBP2,NEU1,HSPA1B,RAB18,ATP6V1D,MAGT1,GOLGA7,LTBP4,SNAP29,FAM3C,PGRMC1,IMPDH1,RBPJ,PSAP,PGAM1,SNAPIN |
| 2.813e-02 | -3.57 | AKAP9 (A-kinase anchoring protein 9) | protein interactions | 10142 | 75 | 19 | 17029 | 2761 |
FGFR1OP,USO1,MAPRE1,TRIP10,SUZ12,DYNLL1,MAGED1,KCNQ1,PCGF1,PRKACA,CALM2,DNAJC10,SUV39H2,HUWE1,CEP55,HNRNPM,TACC3,CSNK1D,CDC5L |
| 2.813e-02 | -3.57 | COMMD1 (copper metabolism domain containing 1) | protein interactions | 150684 | 75 | 19 | 17029 | 2761 |
CCDC93,COMMD10,KAT2A,BIRC3,XIAP,CUL3,CUL1,BRCA1,COMMD5,COMMD4,COMMD6,COMMD8,HSPA4,VPS26C,TFDP1,CLU,SLC12A2,CDKN2A,VPS29 |
| 2.813e-02 | -3.57 | EAF1 (ELL associated factor 1) | protein interactions | 85403 | 75 | 19 | 17029 | 2761 |
SART1,ELL2,ASPM,PIP4K2C,C1orf35,DDX20,EIF2AK1,EAF2,LUC7L,PIP4K2A,APP,GTF2F1,MFAP1,LUC7L3,CABIN1,AFF1,ICE2,CPSF4,LUC7L2 |
| 2.813e-02 | -3.57 | SMC2 (structural maintenance of chromosomes 2) | protein interactions | 10592 | 75 | 19 | 17029 | 2761 |
H2AFZ,FOXM1,SDC2,PTP4A3,IRF3,CAPZA2,PLEC,NCAPG,PSMC4,RPA1,RPA2,SMC3,CCP110,YBX1,CRY2,SSSCA1,CDC5L,ABCC5,SMC4 |
| 2.813e-02 | -3.57 | CLTB (clathrin light chain B) | protein interactions | 1212 | 75 | 19 | 17029 | 2761 |
MAPRE1,PDAP1,MYH9,CSNK2A1,CAPZA2,ANLN,SEC16A,PICALM,APPL1,PI4K2A,SMC3,MYO18A,PQBP1,SLC25A19,AP2B1,GTSE1,ARRB2,AP2S1,NUMB |
| 2.816e-02 | -3.57 | thyroid-chronic_thyroiditis | COSMIC cancer mutations | thyroid-chronic_thyroiditis | 50 | 13 | 17385 | 2587 |
GNAS,FGFR3,RB1,NRAS,CCDC6,PTEN,VHL,PTPN11,STK11,KRAS,SMAD4,HRAS,CDKN2A |
| 2.816e-02 | -3.57 | chronic_thyroiditis | COSMIC cancer mutations | chronic_thyroiditis | 50 | 13 | 17385 | 2587 |
GNAS,FGFR3,RB1,NRAS,CCDC6,PTEN,VHL,PTPN11,STK11,KRAS,SMAD4,HRAS,CDKN2A |
| 2.820e-02 | -3.57 | RECQL4 (RecQ like helicase 4) | protein interactions | 9401 | 28 | 9 | 17029 | 2761 |
TERF2IP,CDC16,UBR2,KCTD17,FBL,MAPK14,LUC7L,TERF1,POT1 |
| 2.820e-02 | -3.57 | ZNF483 (zinc finger protein 483) | protein interactions | 158399 | 28 | 9 | 17029 | 2761 |
ZNF496,ZNF445,ZKSCAN1,DGCR8,MECP2,ECPAS,APP,CCDC59,ZNF174 |
| 2.820e-02 | -3.57 | NIPSNAP3A (nipsnap homolog 3A) | protein interactions | 25934 | 28 | 9 | 17029 | 2761 |
SDHB,GOLM1,KIFAP3,IMMT,GATC,EPHX2,KCMF1,PPA2,MRPL12 |
| 2.820e-02 | -3.57 | HIC1 (HIC ZBTB transcriptional repressor 1) | protein interactions | 3090 | 28 | 9 | 17029 | 2761 |
CHD3,MTA1,SUZ12,PIAS2,ARID1A,UBE2I,RBBP4,MBD3,STAT3 |
| 2.820e-02 | -3.57 | ATP5MD (ATP synthase membrane subunit DAPIT) | protein interactions | 84833 | 28 | 9 | 17029 | 2761 |
CHCHD2,NDUFA4,UNK,UBQLN4,SPRYD4,ATP5F1A,MPHOSPH8,REEP5,CBX4 |
| 2.820e-02 | -3.57 | RALGDS (ral guanine nucleotide dissociation stimulator) | protein interactions | 5900 | 28 | 9 | 17029 | 2761 |
PDPK1,AFDN,RAP1A,KRAS,RIT1,ARRB2,HRAS,FADD,MAPK3 |
| 2.820e-02 | -3.57 | Tipin (timeless interacting protein) | protein interactions | 66131 | 28 | 9 | 17029 | 2761 |
YIF1A,RPA2,MAGED2,CLSPN,TIMELESS,BCLAF1,THRAP3,CHMP2B,GINS4 |
| 2.820e-02 | -3.57 | YPEL5 (yippee like 5) | protein interactions | 51646 | 28 | 9 | 17029 | 2761 |
GID8,RMND5A,RAB8A,MKLN1,SYNCRIP,GPS2,DDX5,CTSA,ARMC8 |
| 2.820e-02 | -3.57 | RCAN1 (regulator of calcineurin 1) | protein interactions | 1827 | 28 | 9 | 17029 | 2761 |
PPP3CA,PPP3R1,ARMT1,FAM122A,USP22,PPP3CB,TOLLIP,APP,MAPK3 |
| 2.820e-02 | -3.57 | SLC25A12 (solute carrier family 25 member 12) | protein interactions | 8604 | 28 | 9 | 17029 | 2761 |
GNAS,IMMT,RHOA,TM9SF4,ZNF746,PELO,NDUFA4,ATF2,CHCHD6 |
| 2.820e-02 | -3.57 | NOL11 (nucleolar protein 11) | protein interactions | 25926 | 28 | 9 | 17029 | 2761 |
GOLGA4,PCM1,UTP15,HNRNPF,BRCA1,FBL,APP,UTP4,IFI16 |
| 2.820e-02 | -3.57 | GZMB (granzyme B) | protein interactions | 3002 | 28 | 9 | 17029 | 2761 |
HSPA4,PRKDC,SRGN,UBE4A,PTGES3,UBE4B,XRCC4,LMNA,XRCC5 |
| 2.820e-02 | -3.57 | PCID2 (PCI domain containing 2) | protein interactions | 55795 | 28 | 9 | 17029 | 2761 |
SMAD2,NEK6,SNX2,EID1,CUL3,TTC4,UBE4B,KIF11,IFI16 |
| 2.820e-02 | -3.57 | LMAN2 (lectin, mannose binding 2) | protein interactions | 10960 | 28 | 9 | 17029 | 2761 |
RPA2,TM9SF4,TMED10,FLOT1,PDIA6,SPPL2B,TMED2,ISG15,RPA1 |
| 2.820e-02 | -3.57 | CHMP1B (charged multivesicular body protein 1B) | protein interactions | 57132 | 28 | 9 | 17029 | 2761 |
CHMP4B,SNRNP200,ORC1,VPS4A,WDR5,TFG,SUCLG1,RAB11A,SSRP1 |
| 2.820e-02 | -3.57 | NCLN (nicalin) | protein interactions | 56926 | 28 | 9 | 17029 | 2761 |
EPRS,HUWE1,ILF3,AGPAT3,XRCC3,RPN2,MCM2,METTL9,GLMP |
| 2.820e-02 | -3.57 | NFKBIL1 (NFKB inhibitor like 1) | protein interactions | 4795 | 28 | 9 | 17029 | 2761 |
KIF2A,THOC1,RFXANK,ZRANB2,JMJD6,GEMIN4,ARRB2,LUC7L,PIP4K2A |
| 2.820e-02 | -3.57 | VMA21 (VMA21, vacuolar ATPase assembly factor) | protein interactions | 203547 | 28 | 9 | 17029 | 2761 |
SEPT9,TMEM216,ATP6V0A2,ATP6V0C,COA7,ATP6V0E1,TMEM9,ATP6V0D1,EVC2 |
| 2.821e-02 | -3.57 | Cystathionine Beta-Synthase Deficiency | SMPDB pathways | SMP00177 | 19 | 7 | 992 | 167 |
MAT2B,SRM,AHCY,MTR,DNMT1,MAT2A,AMD1 |
| 2.821e-02 | -3.57 | Glycine N-methyltransferase Deficiency | SMPDB pathways | SMP00222 | 19 | 7 | 992 | 167 |
MAT2B,SRM,AHCY,MTR,DNMT1,MAT2A,AMD1 |
| 2.821e-02 | -3.57 | S-Adenosylhomocysteine (SAH) Hydrolase Deficiency | SMPDB pathways | SMP00214 | 19 | 7 | 992 | 167 |
MAT2B,SRM,AHCY,MTR,DNMT1,AMD1,MAT2A |
| 2.821e-02 | -3.57 | Methionine Adenosyltransferase Deficiency | SMPDB pathways | SMP00221 | 19 | 7 | 992 | 167 |
MAT2B,SRM,AHCY,MTR,DNMT1,MAT2A,AMD1 |
| 2.821e-02 | -3.57 | Methionine Metabolism | SMPDB pathways | SMP00033 | 19 | 7 | 992 | 167 |
MAT2B,SRM,AHCY,MTR,DNMT1,MAT2A,AMD1 |
| 2.821e-02 | -3.57 | Hypermethioninemia | SMPDB pathways | SMP00341 | 19 | 7 | 992 | 167 |
MAT2B,SRM,AHCY,MTR,DNMT1,AMD1,MAT2A |
| 2.821e-02 | -3.57 | Homocystinuria-megaloblastic anemia due to defect in cobalamin metabolism- cblG complementation type | SMPDB pathways | SMP00570 | 19 | 7 | 992 | 167 |
MAT2B,SRM,AHCY,MTR,DNMT1,MAT2A,AMD1 |
| 2.821e-02 | -3.57 | Methylenetetrahydrofolate Reductase Deficiency (MTHFRD) | SMPDB pathways | SMP00340 | 19 | 7 | 992 | 167 |
MAT2B,SRM,AHCY,MTR,DNMT1,MAT2A,AMD1 |
| 2.822e-02 | -3.57 | GO_MOTOR_ACTIVITY | MSigDB lists | GO_MOTOR_ACTIVITY | 129 | 28 | 17377 | 2626 |
KIF3B,DYNLL1,DCTN2,KIF15,MYH9,KLC1,KIF23,KIF2C,MYO9B,KIF11,MYL6B,MYO1F,KIFC1,KIF5B,KIF2A,STARD9,SMC3,KIF18A,KIF18B,PIN1,KIF13B,KIF14,KIF22,MYO9A,DYNC1LI2,DNAL4,MYO5A,DCTN1 |
| 2.822e-02 | -3.57 | GSE2770_IL12_VS_IL4_TREATED_ACT_CD4_TCELL_2H_UP | MSigDB lists | GSE2770_IL12_VS_IL4_TREATED_ACT_CD4_TCELL_2H_UP | 129 | 28 | 17377 | 2626 |
EXOC3,CDC40,LAP3,DBF4,CAMSAP1,FBXO9,CREBL2,CDK13,ATG2B,DIDO1,KCMF1,ARF4,ECH1,ERH,CLUAP1,ATP6V1D,FUT8,KBTBD7,GLG1,CNPY4,CBWD1,ATP6V0C,PIEZO1,HEXA,ATP6V0E1,CFL1,DDB1,LUC7L2 |
| 2.822e-02 | -3.57 | ZHONG_SECRETOME_OF_LUNG_CANCER_AND_FIBROBLAST | MSigDB lists | ZHONG_SECRETOME_OF_LUNG_CANCER_AND_FIBROBLAST | 129 | 28 | 17377 | 2626 |
KCTD7,CYTIP,TIMP2,RHOA,AGRN,LAP3,WDR1,MDH2,LDHA,PSMA1,GLO1,APP,PARK7,PSMB3,PRDX1,LMNA,CHAF1A,GLOD4,NUCB1,FAM3C,AKR1B1,CANT1,YWHAZ,ACTB,CLU,GPI,CD81,YWHAH |
| 2.823e-02 | -3.57 | V$CREB_Q3 | MSigDB lists | V$CREB_Q3 | 231 | 46 | 17377 | 2626 |
C1orf74,PKP4,HNRNPAB,THOC1,SRSF6,ANKH,ADO,YTHDC2,RRM1,KLHL18,USP48,GGPS1,PIP4K2A,XPR1,CDKN2C,CDC42,MECR,AP2B1,CDKN1B,STAT3,ARID4A,DCTN1,RBM15B,EIF5A,POU2AF1,CPNE1,TMEM39A,PRRC2A,TLK1,SCFD2,RNPS1,NUP155,RAB1A,USP36,IWS1,BRMS1,MBIP,HPS5,COX8A,SMPD4,EHD4,MZT2B,ATP6V0E1,ALS2,TMEM33,CWC25 |
| 2.824e-02 | -3.57 | cofactor metabolic process | biological process | GO:0051186 | 489 | 90 | 17256 | 2622 |
COX15,MMACHC,PPCS,SUCLG1,MDH2,UROD,SLC2A1,MCCC1,ADPGK,GLRX3,PARK7,CD320,FLAD1,GOT2,PPCDC,AKR1B1,SUCLG2,NFU1,TECR,AHCYL1,TALDO1,GPD1L,TMEM14C,KCNAB2,ACSL5,PPT1,COQ10B,CPOX,GLO1,OGDH,PDHX,MPC1,MAT2A,PRDX5,MLYCD,DHTKD1,PDXK,DHFR2,SLC25A39,PFKP,GALK1,GCLM,NADSYN1,MUT,TKT,PM20D2,CHAC2,SPR,PMVK,RSAD1,MAT2B,PDXP,GSTK1,CLIC4,GART,COQ4,ATIC,AHCY,RNLS,SLC25A1,ABCC1,LDHB,ELOVL5,ATP5IF1,COQ8A,ACSL3,AMD1,LDHA,NADK2,EIF2AK1,PKM,HAGH,MTR,PRDX1,CYB5A,CAT,SLC19A1,MBIP,MTHFD2,PRDX3,DBI,ACLY,NAXE,ACAT1,MDH1,GPI,PARP10,PGAM1,ACSF2,PDSS2 |
| 2.825e-02 | -3.57 | YGCANTGCR_UNKNOWN | MSigDB lists | YGCANTGCR_UNKNOWN | 118 | 26 | 17377 | 2626 |
CPNE1,EIF5A,ATP13A1,EWSR1,ANXA6,CAST,MAGED1,CTCF,TOPORS,WDR81,STX16,EIF4G2,SFXN5,APP,MAT2A,CSDE1,CALM2,KPNA1,PCM1,CCP110,TTC9C,PSAP,TMEM14A,RTN3,PURA,PDCL3 |
| 2.827e-02 | -3.57 | KEGG_REGULATION_OF_ACTIN_CYTOSKELETON | MSigDB lists | KEGG_REGULATION_OF_ACTIN_CYTOSKELETON | 208 | 42 | 17377 | 2626 |
WASF2,PPP1R12A,RAF1,VAV2,RAC1,MYH9,NCKAP1,ITGB5,PIP4K2A,PIP5K1C,CRKL,VAV1,FGFR3,ITGB8,CDC42,ARPC5,PIK3R2,ARHGEF1,PIKFYVE,F2R,CFL1,CYFIP1,NRAS,RHOA,PIP4K2C,EZR,KRAS,ARHGEF12,CYFIP2,ARPC1A,MAP2K2,MAPK3,GNA12,WAS,CSK,LIMK1,ITGB1,ACTB,ROCK1,MAPK1,HRAS,MYL12B |
| 2.831e-02 | -3.56 | MAGED2 (MAGE family member D2) | protein interactions | 10916 | 80 | 20 | 17029 | 2761 |
USP7,NSMCE4A,CYLD,EID1,MAGED1,LAGE3,CUL3,DNAJB1,MCM2,OGFR,SRRT,GNAS,NAP1L1,MCM5,ZNF746,ACLY,RPAP1,FKBP5,NAP1L4,TUBB |
| 2.831e-02 | -3.56 | DNMT3L (DNA methyltransferase 3 like) | protein interactions | 29947 | 80 | 20 | 17029 | 2761 |
MAX,DNMT3A,MECP2,LDB1,E2F3,MEF2A,CREBL2,MEF2D,ETS1,CREM,MAFK,E2F4,GMEB1,NFIL3,CREB1,YY1,SMAD1,GTF2H2,ATF2,SMAD4 |
| 2.833e-02 | -3.56 | DNAJA2 (DnaJ heat shock protein family (Hsp40) member A2) | protein interactions | 10294 | 90 | 22 | 17029 | 2761 |
HSPH1,CYLD,PTPN18,VHL,POC1A,ABCF2,CUL3,BRCA1,DNAJB1,MCM2,PSMC4,WWP2,RB1,SMAD2,SMC3,PSMA6,HSPA4,SHC1,HUWE1,TERF2,NUDC,DCTN1 |
| 2.833e-02 | -3.56 | UCHL3 (ubiquitin C-terminal hydrolase L3) | protein interactions | 7347 | 90 | 22 | 17029 | 2761 |
PPIB,UNK,MAPRE1,XIAP,EZR,UBE2V1,UBE4B,USP48,USP21,USP5,HINT1,NT5DC1,TTC9C,USP20,ZRANB2,TAGLN2,COPS6,SMAD1,AHCYL1,SSSCA1,GPX4,USP34 |
| 2.833e-02 | -3.56 | XPO7 (exportin 7) | protein interactions | 23039 | 90 | 22 | 17029 | 2761 |
PDPK1,SLC39A9,HSPH1,USO1,POLK,TLK1,PTP4A3,JMJD6,DNAJB1,UBE2I,SH3GLB1,GART,VPS26C,DPYSL2,SEC24C,PPM1G,AP2B1,NUP153,RP2,USP11,FAF1,CARM1 |
| 2.833e-02 | -3.56 | KEGG_VEGF_SIGNALING_PATHWAY | MSigDB lists | KEGG_VEGF_SIGNALING_PATHWAY | 75 | 18 | 17377 | 2626 |
PPP3CA,NRAS,MAPKAPK3,AKT2,RAF1,RAC1,KRAS,NFATC2,PPP3CB,MAPK14,MAP2K2,MAPK3,NFATC3,CDC42,PIK3R2,PPP3R1,MAPK1,HRAS |
| 2.836e-02 | -3.56 | soft_tissue-fibrous_tissue_and_uncertain_origin-alveolar_soft_part_sarcoma | COSMIC cancer mutations | soft_tissue-fibrous_tissue_and_uncertain_origin-alveolar_soft_part_sarcoma | 45 | 12 | 17385 | 2587 |
GNAS,FGFR3,RB1,NRAS,PTEN,VHL,PTPN11,STK11,KRAS,SMAD4,HRAS,CDKN2A |
| 2.836e-02 | -3.56 | alveolar_soft_part_sarcoma | COSMIC cancer mutations | alveolar_soft_part_sarcoma | 45 | 12 | 17385 | 2587 |
GNAS,FGFR3,RB1,NRAS,PTEN,VHL,PTPN11,KRAS,STK11,HRAS,SMAD4,CDKN2A |
| 2.837e-02 | -3.56 | Cyclophilin-type_PPIase | interpro domains | IPR024936 | 21 | 7 | 18492 | 2768 |
PPIF,PPIB,PPWD1,CWC27,PPIG,PPIE,PPIL2 |
| 2.837e-02 | -3.56 | GSN (gelsolin) | protein interactions | 2934 | 85 | 21 | 17029 | 2761 |
COX15,PPP1R18,THOC1,SESTD1,MYH9,CAPZA2,VDAC1,MPG,APP,CFLAR,SDHB,EIF3K,MDM2,UBE2Q2,VASP,CSK,MYO18A,BCL7C,ACTB,CDK2,ARRB2 |
| 2.837e-02 | -3.56 | ZFC3H1 (zinc finger C3H1-type containing) | protein interactions | 196441 | 85 | 21 | 17029 | 2761 |
CCDC57,ERCC1,THOC1,SRGN,SLBP,CSNK2A1,MRPS14,SRRT,APP,PABPC4,SPAG5,PPP2CA,EXOSC7,UPF1,GOLGA2,VPS26B,EXOSC1,PPP2R2D,ZC3H3,TACC3,SRPK2 |
| 2.837e-02 | -3.56 | SLC9A3R2 (SLC9A3 regulator 2) | protein interactions | 9351 | 85 | 21 | 17029 | 2761 |
PDPK1,COPS8,KIF3B,RPL29,PPT1,EZR,NUSAP1,ADRB2,TOMM40,TAZ,PRKACA,NUDT19,NDUFV1,PTEN,SIAH1,ATXN2L,SEPT11,KIFAP3,UBE2M,HRAS,ANXA11 |
| 2.842e-02 | -3.56 | RS domain binding | molecular function | GO:0050733 | 5 | 3 | 17224 | 2647 |
LUC7L,SRSF1,SRSF10 |
| 2.842e-02 | -3.56 | thioredoxin peroxidase activity | molecular function | GO:0008379 | 5 | 3 | 17224 | 2647 |
PRDX3,PRDX5,PRDX1 |
| 2.842e-02 | -3.56 | U1 snRNP binding | molecular function | GO:1990446 | 5 | 3 | 17224 | 2647 |
SNRPD3,SNRNP70,SNRPA |
| 2.842e-02 | -3.56 | uridine kinase activity | molecular function | GO:0004849 | 5 | 3 | 17224 | 2647 |
UCK1,UPRT,UCK2 |
| 2.842e-02 | -3.56 | S-adenosyl-L-methionine binding | molecular function | GO:1904047 | 5 | 3 | 17224 | 2647 |
SUV39H2,METTL3,METTL14 |
| 2.842e-02 | -3.56 | BH3 domain binding | molecular function | GO:0051434 | 5 | 3 | 17224 | 2647 |
MCL1,BCL2,BCL2L1 |
| 2.842e-02 | -3.56 | 1-acylglycerophosphocholine O-acyltransferase activity | molecular function | GO:0047184 | 5 | 3 | 17224 | 2647 |
TAZ,LPCAT1,LPCAT4 |
| 2.842e-02 | -3.56 | nucleotide phosphatase activity, acting on free nucleotides | molecular function | GO:0098519 | 5 | 3 | 17224 | 2647 |
DUSP11,NTPCR,PDXP |
| 2.842e-02 | -3.56 | double-stranded methylated DNA binding | molecular function | GO:0010385 | 5 | 3 | 17224 | 2647 |
H2AFY,MBD1,MECP2 |
| 2.842e-02 | -3.56 | beta-N-acetylhexosaminidase activity | molecular function | GO:0004563 | 5 | 3 | 17224 | 2647 |
HEXA,GM2A,HEXB |
| 2.842e-02 | -3.56 | ATPase inhibitor activity | molecular function | GO:0042030 | 5 | 3 | 17224 | 2647 |
TSC1,ATP5IF1,FNIP2 |
| 2.842e-02 | -3.56 | MHC class Ib protein binding | molecular function | GO:0023029 | 5 | 3 | 17224 | 2647 |
TAP2,FAM49B,TAP1 |
| 2.846e-02 | -3.56 | NEDD4 (neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase) | protein interactions | 4734 | 303 | 62 | 17029 | 2761 |
UBE2D3,PDCD6IP,ANKRD13D,SCAMP3,THOC1,CASP6,RAF1,RAC1,CUL1,THRAP3,DAZAP2,MAP1LC3B,BECN1,RAPGEF6,MRPL19,PIP5K1C,CDK5,ABL2,MDM2,KMT5C,PTEN,NSRP1,MTMR4,SIVA1,N4BP2,UBE2M,KCNAB2,LUC7L2,EBAG9,RPAP3,AMPD2,PLK1,SEPT9,TSTA3,RBX1,MAPKAPK3,RAD51AP1,WBP2,GBA,RTF1,ARID1A,KCNQ1,ADRB2,WBP1,FKBP3,MARK2,RPSA,POLR2A,ISG15,EPRS,HGS,SMAD2,CLK3,ARRDC1,TRIM52,DVL1,YY1,MAP3K5,SMAD1,GUCD1,ARRB2,CSNK1D |
| 2.853e-02 | -3.56 | GO_NEGATIVE_REGULATION_OF_CANONICAL_WNT_SIGNALING_PATHWAY | MSigDB lists | GO_NEGATIVE_REGULATION_OF_CANONICAL_WNT_SIGNALING_PATHWAY | 157 | 33 | 17377 | 2626 |
NPHP4,CYLD,PSMA8,RBX1,NKD2,PSMB7,CUL3,PSMA1,ZNRF3,CSNK1A1,PSMD9,MAPK14,PSMB9,FOXO3,SCYL2,MAD2L2,PSMB3,FZD6,PSMC4,PFDN5,PSMD2,PSMD1,PSMA6,RPS27A,PSMD8,AXIN1,WNT5B,PSMD3,SIAH2,AXIN2,DVL1,PSMC1,DVL2 |
| 2.853e-02 | -3.56 | GO_ACTIN_FILAMENT_ORGANIZATION | MSigDB lists | GO_ACTIN_FILAMENT_ORGANIZATION | 157 | 33 | 17377 | 2626 |
CORO7,ADD1,ACTR3,RAC1,PAWR,ARF1,ITGB5,MAD2L2,JMY,PDXP,VASP,PDCD10,CDC42,ARPC5,ARHGEF2,BCL2,CORO1A,TTC17,ABI1,MICAL3,CFL1,PPP1R9B,RHOA,NCK1,CUL3,WIPF1,EZR,ARPC1A,DPYSL3,WAS,ARAP1,ITGB1,RUFY3 |
| 2.860e-02 | -3.55 | GSE37533_UNTREATED_VS_PIOGLIZATONE_TREATED_CD4_TCELL_PPARG1_AND_FOXP3_TRASDUCED_DN | MSigDB lists | GSE37533_UNTREATED_VS_PIOGLIZATONE_TREATED_CD4_TCELL_PPARG1_AND_FOXP3_TRASDUCED_DN | 191 | 39 | 17377 | 2626 |
WASF2,NPHP4,GGNBP2,REPS2,GORASP1,TSC22D3,DAP,ABCC10,HABP4,NENF,XPNPEP3,AP1B1,ITGB5,PDXDC1,INTS1,PRDM4,PARL,CENPM,GNAI2,CNPY3,CTDSP2,ZC3H3,TPCN1,IMPA2,SLC25A1,ABCC5,PTPN18,PARP4,TOP3A,ABHD11,MPG,POLR2A,MAN2A2,ZNF862,SGSH,WAS,DUSP3,CAPN1,RNF114 |
| 2.860e-02 | -3.55 | GSE14769_UNSTIM_VS_40MIN_LPS_BMDM_DN | MSigDB lists | GSE14769_UNSTIM_VS_40MIN_LPS_BMDM_DN | 191 | 39 | 17377 | 2626 |
IER2,ARID5A,RGS1,RNF103,ATPAF1,CFLAR,CHKA,FANCL,MEX3C,CENPJ,CITED2,ATF2,GPD1L,TIPARP,POC5,RYBP,IFRD1,BIRC3,ETV3,TNFAIP3,BTG2,ACSL3,MCL1,ANLN,ODC1,KLF6,ARL5B,ZFAND5,HSPA1B,SMAD2,L3MBTL3,GADD45B,FAM83D,SIAH2,HMGB2,VPS4A,TOB1,FAM72A,S100PBP |
| 2.860e-02 | -3.55 | GSE15324_ELF4_KO_VS_WT_ACTIVATED_CD8_TCELL_DN | MSigDB lists | GSE15324_ELF4_KO_VS_WT_ACTIVATED_CD8_TCELL_DN | 191 | 39 | 17377 | 2626 |
PRKAB1,LIME1,HJURP,DBF4,KIF23,MEF2A,MAN2B1,ADD3,PTEN,RIMS3,PHTF1,NSFL1C,SCYL3,GCC1,FGFR1OP2,S100A6,TSHZ1,DDX28,PIGT,NQO2,BTG2,SCFD2,ARHGDIB,TXNL4A,ZDHHC3,SH3GLB1,ASF1B,NCDN,ALKBH6,TMEM184C,SEPT1,FBXO41,NSMCE2,STAT1,BRD9,CCNB2,LONP2,MYL12B,STARD3NL |
| 2.860e-02 | -3.55 | GSE21670_UNTREATED_VS_IL6_TREATED_CD4_TCELL_DN | MSigDB lists | GSE21670_UNTREATED_VS_IL6_TREATED_CD4_TCELL_DN | 191 | 39 | 17377 | 2626 |
UBE2D3,BCL2L12,CYTIP,DCAF15,CXXC1,MUM1,HABP4,ACAP1,SMC6,PIP4K2A,SPPL2A,RAB8A,KDM2A,PHTF1,CDKN1B,CNN2,SLC26A2,PIK3IP1,CHTOP,PLCL2,PACS2,CAMK2G,PHF20L1,RB1CC1,TAOK1,POLR3GL,LRRC8A,PACS1,MEF2D,ARID1A,TAZ,GALNT2,PDLIM1,STK38,CAMKMT,SAMD8,ZBTB11,SMAD4,PDCD4 |
| 2.860e-02 | -3.55 | GSE18893_TCONV_VS_TREG_2H_CULTURE_DN | MSigDB lists | GSE18893_TCONV_VS_TREG_2H_CULTURE_DN | 191 | 39 | 17377 | 2626 |
DDX58,RAB14,PARP12,SCOC,TAP1,SLC35B1,B4GALT4,DCUN1D4,ABHD16A,MAN1A1,INPP5A,LPIN2,RAD23B,FEM1B,SYTL3,ARL5A,CGGBP1,RPAP3,STAU1,ERMP1,TRAFD1,SNX2,TSPYL4,LRRC8A,RAB1A,ARPC1A,SH3GLB1,SUPT16H,SCARB2,ZHX1,HIPK2,ZNF367,CTBS,SEL1L,ADAM9,MAP3K5,BRWD3,NRBP1,MYL12B |
| 2.860e-02 | -3.55 | GSE22886_DAY0_VS_DAY1_MONOCYTE_IN_CULTURE_UP | MSigDB lists | GSE22886_DAY0_VS_DAY1_MONOCYTE_IN_CULTURE_UP | 191 | 39 | 17377 | 2626 |
RPS2,RPLP2,CAST,TOR3A,HMGN3,HAUS4,SLC12A9,RGS2,MAPK14,FAM8A1,BZW2,PCYOX1L,GSTK1,NUP210,ADD3,DUT,FBL,PLCL2,CNPY3,SLC35A1,IMPA2,ADCY7,RPL29,PSRC1,KIAA0040,FRAT2,ICAM2,RHOB,CAT,MTMR3,QARS,STK38,CCDC69,LY75,ZDHHC7,HMGB2,PIEZO1,LTA4H,CHPT1 |
| 2.860e-02 | -3.55 | GSE33292_DN3_THYMOCYTE_VS_TCF1_KO_TCELL_LYMPHOMA_UP | MSigDB lists | GSE33292_DN3_THYMOCYTE_VS_TCF1_KO_TCELL_LYMPHOMA_UP | 191 | 39 | 17377 | 2626 |
SRM,ABCA3,TXN,TMED3,GGA2,OAT,PPP1R16B,TFRC,HDDC2,PNO1,PRNP,FLAD1,EXOSC7,ATIC,AHCY,PTPRK,TELO2,BIRC3,KAT2A,GALC,CREG1,MAP4K4,WDR18,ABCF2,MRPL12,TMEM147,ICAM2,SH3BP5,HHEX,AHNAK,HSPBP1,SNAP23,STAT6,LY75,IMPDH1,TICAM1,NCLN,NDUFS5,TRAF5 |
| 2.861e-02 | -3.55 | SIRNA_EIF4GI_DN | MSigDB lists | SIRNA_EIF4GI_DN | 91 | 21 | 17377 | 2626 |
MRPL9,TMEM39A,WDYHV1,NEK7,RAB7A,MAP4K3,CDC6,RAB1A,SHCBP1,PDHX,MAN2A2,CDKN2C,SLC31A1,PDCD10,UAP1,ACYP1,PPME1,TANK,SPTSSA,ATP6V0E1,ATMIN |
| 2.865e-02 | -3.55 | REACTOME_AXON_GUIDANCE | MSigDB lists | REACTOME_AXON_GUIDANCE | 237 | 47 | 17377 | 2626 |
RHOG,PLXNC1,AGRN,RPS6KA1,RAF1,RHOC,RAC1,ANK3,TRIO,CSNK2A1,MYH9,PLXNA1,PIP5K1C,PRNP,ABL2,CDK5,VASP,CDC42,SIAH1,DPYSL2,DNM2,AP2B1,CREB1,ST8SIA2,CFL1,SPTAN1,NRAS,RHOA,NCK1,EZR,KRAS,ARHGEF12,MAP2K2,RHOB,MAPK3,DPYSL3,CACNB1,LIMK1,ITGB1,SIAH2,PITPNA,ROCK1,MAPK1,AP2S1,MYL12B,HRAS,NUMB |
| 2.867e-02 | -3.55 | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds | molecular function | GO:0016810 | 149 | 32 | 17224 | 2647 |
ADA2,NADSYN1,WDYHV1,ASAH1,NIT2,SIRT2,PM20D2,DPYSL2,HDAC7,MTA1,ATIC,SAP30L,ARID4A,SAP30,AMPD2,MTA2,MIER1,RCOR1,MIER2,DCTD,AMDHD2,MBD3,DPYSL3,BRMS1,CAT,MTHFD2,CHD3,QRSL1,RBBP4,NGLY1,HDAC2,PDF |
| 2.870e-02 | -3.55 | RFXANK (regulatory factor X associated ankyrin containing protein) | protein interactions | 8625 | 37 | 11 | 17029 | 2761 |
DDOST,PHB2,HUWE1,RAF1,RFXANK,UHRF1BP1,TRIM28,LMNA,HNRNPM,N4BP2L2,DCTN1 |
| 2.870e-02 | -3.55 | LYZL1 (lysozyme like 1) | protein interactions | 84569 | 37 | 11 | 17029 | 2761 |
MANBA,NAGLU,ADAM9,CTR9,TTC17,EDEM2,ARSK,MGAT5,N4BP2L2,DNAJB9,TMEM131 |
| 2.870e-02 | -3.55 | PNMA5 (PNMA family member 5) | protein interactions | 114824 | 37 | 11 | 17029 | 2761 |
MOAP1,CCNC,WDYHV1,PRKAA1,RAD23B,AP1M1,PSMA1,TNPO2,GORASP2,KPNA2,CDC23 |
| 2.870e-02 | -3.55 | FKBP15 (FK506 binding protein 15) | protein interactions | 23307 | 37 | 11 | 17029 | 2761 |
RPA2,COMMD10,FGFR1OP,MIOS,VPS26B,SNAP29,CTR9,PRPF4,MCM2,VPS29,RPA1 |
| 2.870e-02 | -3.55 | UTP15 (UTP15, small subunit processome component) | protein interactions | 84135 | 37 | 11 | 17029 | 2761 |
EIF3K,NOL11,TBL3,SUZ12,CUL3,FBL,BRIX1,UTP4,RBM4,IFI16,KRR1 |
| 2.870e-02 | -3.55 | FSHR (follicle stimulating hormone receptor) | protein interactions | 2492 | 37 | 11 | 17029 | 2761 |
SLC12A7,NAGPA,GRK2,RPS27A,DAD1,AKT2,PPP1R15B,APPL2,UPK3BL1,APPL1,SNX14 |
| 2.870e-02 | -3.55 | DDX50 (DExD-box helicase 50) | protein interactions | 79009 | 37 | 11 | 17029 | 2761 |
NOL12,STAU1,KMT2E,RBM34,CUL3,KRAS,TARDBP,PRKRA,LUC7L,SRPK2,CAND1 |
| 2.870e-02 | -3.55 | DTX3L (deltex E3 ubiquitin ligase 3L) | protein interactions | 151636 | 37 | 11 | 17029 | 2761 |
UBE2D3,RPA2,UBE2E2,HGS,JAK1,STAT1,UBE2I,H2AFV,NCAPG,STAM,RPA1 |
| 2.870e-02 | -3.55 | CRTC2 (CREB regulated transcription coactivator 2) | protein interactions | 200186 | 37 | 11 | 17029 | 2761 |
ZBTB21,PPP3CA,MDM2,WDYHV1,KIF13B,PRKAA1,PPP3R1,GTSE1,YWHAZ,PPP3CB,GIGYF1 |
| 2.870e-02 | -3.55 | USP42 (ubiquitin specific peptidase 42) | protein interactions | 84132 | 37 | 11 | 17029 | 2761 |
MDM2,TEX10,WDR18,YTHDC2,MRPS26,JMJD6,BMS1,PCGF1,AHCYL1,MRPS14,CPNE3 |
| 2.870e-02 | -3.55 | PIDD1 (p53-induced death domain protein 1) | protein interactions | 55367 | 37 | 11 | 17029 | 2761 |
RPAP3,TELO2,PCNA,KEAP1,PRKDC,PPP6C,TRIM32,FADD,DDB1,PRDX1,FANCI |
| 2.870e-02 | -3.55 | RAB3IL1 (RAB3A interacting protein like 1) | protein interactions | 5866 | 37 | 11 | 17029 | 2761 |
RAB8A,CCDC57,TRAPPC9,FAM49B,ODF2,SUGP2,RAB3IP,PPFIA3,RAB11A,RAB3IL1,OPTN |
| 2.870e-02 | -3.55 | PRSS23 (serine protease 23) | protein interactions | 11098 | 37 | 11 | 17029 | 2761 |
NOP9,PDPK1,TCF12,HSPA4,PHF23,CTR9,RACGAP1,ACTB,FXR1,APP,CHP1 |
| 2.870e-02 | -3.55 | PRMT8 (protein arginine methyltransferase 8) | protein interactions | 56341 | 37 | 11 | 17029 | 2761 |
EWSR1,SYNCRIP,HNRNPR,VHL,DCAF8,HNRNPUL2,DHX9,BCLAF1,THRAP3,CHTOP,COIL |
| 2.870e-02 | -3.55 | SNF8 (SNF8, ESCRT-II complex subunit) | protein interactions | 11267 | 37 | 11 | 17029 | 2761 |
SUV39H2,DUS3L,GOLGA2,HARS,METTL14,PSMD3,EFTUD2,MCM2,VPS25,DVL2,GTF2F1 |
| 2.870e-02 | -3.55 | CLEC11A (C-type lectin domain containing 11A) | protein interactions | 6320 | 37 | 11 | 17029 | 2761 |
PKP4,TRAF7,FBXO28,GALC,AKAP8,SUGP2,AMD1,XIAP,IKBIP,ZNF518A,BIRC2 |
| 2.870e-02 | -3.55 | PBK (PDZ binding kinase) | protein interactions | 55872 | 37 | 11 | 17029 | 2761 |
RHOBTB3,ZFP64,PTEN,GPS2,E2F4,RAF1,H2AFX,ARRDC1,CCNB1,SMAD4,USP5 |
| 2.870e-02 | -3.55 | IST1 (IST1, ESCRT-III associated factor) | protein interactions | 9798 | 37 | 11 | 17029 | 2761 |
MIB2,TIMM13,RAB7A,CAPN7,BTF3L4,PTAR1,ATXN1,ANAPC2,CHMP4B,VPS4A,TFG |
| 2.870e-02 | -3.55 | RFX3 (regulatory factor X3) | protein interactions | 5991 | 37 | 11 | 17029 | 2761 |
PLK1,EWSR1,MTA2,MBD2,RTCB,VPS45,TAF6L,CREB1,CFAP20,HDAC2,PTOV1 |
| 2.870e-02 | -3.55 | RASSF9 (Ras association domain family member 9) | protein interactions | 9182 | 37 | 11 | 17029 | 2761 |
DVL1,TP53BP2,TCOF1,RBBP4,PCBP1,KCMF1,DVL2,PARD3,DDB1,SAPCD2,PTOV1 |
| 2.871e-02 | -3.55 | GSE17974_CTRL_VS_ACT_IL4_AND_ANTI_IL12_1H_CD4_TCELL_DN | MSigDB lists | GSE17974_CTRL_VS_ACT_IL4_AND_ANTI_IL12_1H_CD4_TCELL_DN | 174 | 36 | 17377 | 2626 |
TP53RK,ADO,MYNN,CHAC2,ZNF267,TMEM165,WRB,CREM,FBXO5,C14orf119,IRF4,MLX,VMP1,TTC9C,ZNF200,GEMIN6,ZNF189,PPAN,ANKRD37,KLF10,C16orf72,TEX10,CRNKL1,RABIF,PFKFB3,KIAA1586,SLC17A5,TOLLIP,ARL5B,FADD,BBS12,TMEM184C,MFAP1,ZNF436,MLYCD,ZSWIM3 |
| 2.876e-02 | -3.55 | EPS15 (epidermal growth factor receptor pathway substrate 15) | protein interactions | 2060 | 152 | 34 | 17029 | 2761 |
UBE2D3,CORO7,MAPRE1,CDC40,REPS2,MYH9,EPN1,AGFG1,UBQLN2,AP1B1,MAPK14,RAD23A,CRKL,DNM2,GTSE1,AP2B1,CLTB,RNF26,TGFB1,NAGPA,MOB4,CAPZA2,ANLN,PICALM,PRDX1,HSPA1B,NECAP2,OPTN,HGS,MAP4,ACTB,AP2S1,TUBB,NUMB |
| 2.876e-02 | -3.55 | cytoplasmic vesicle lumen | cellular component | GO:0060205 | 337 | 63 | 18223 | 2701 |
ADA2,MIF,HSPH1,GMFG,HEXB,SRGN,OLA1,NIT2,MAN2B1,NHLRC3,GYG1,MAPK14,APP,FERMT3,PCYOX1L,GNS,PA2G4,PSMD2,PSMD1,ARPC5,HUWE1,OSTF1,CNN2,APOOL,MVP,GM2A,SPTAN1,TGFB1,CYFIP1,FTL,CCT2,TIMP2,FAM49B,CREG1,ARHGAP45,PPIE,PSMB7,C1orf35,HEBP2,PKM,TOLLIP,ARMC8,CCT8,NEU1,CAND1,XRCC5,MAGED2,CAT,DSN1,PSMD3,FAM3C,ACLY,IMPDH1,CAB39,CANT1,CTSA,CLU,GPI,PDXK,ROCK1,PGAM1,MAPK1,TUBB |
| 2.887e-02 | -3.55 | TRNASYNTHGLU | prints domains | PR00987 | 3 | 2 | 4652 | 473 |
EPRS,QARS |
| 2.887e-02 | -3.55 | AMYLOIDA4 | prints domains | PR00203 | 3 | 2 | 4652 | 473 |
APLP2,APP |
| 2.887e-02 | -3.55 | EUKARYTPORIN | prints domains | PR00185 | 3 | 2 | 4652 | 473 |
VDAC1,VDAC2 |
| 2.887e-02 | -3.55 | CD36FAMILY | prints domains | PR01609 | 3 | 2 | 4652 | 473 |
SCARB2,SCARB1 |
| 2.887e-02 | -3.55 | DISHEVELLED | prints domains | PR01760 | 3 | 2 | 4652 | 473 |
DVL1,DVL2 |
| 2.887e-02 | -3.55 | FACTINCAPA | prints domains | PR00191 | 3 | 2 | 4652 | 473 |
CAPZA2,CAPZA1 |
| 2.890e-02 | -3.54 | GO_PHOSPHATE_TRANSMEMBRANE_TRANSPORTER_ACTIVITY | MSigDB lists | GO_PHOSPHATE_TRANSMEMBRANE_TRANSPORTER_ACTIVITY | 30 | 9 | 17377 | 2626 |
ANKH,SLC35B4,SLC25A19,SLC35B2,SLC35B1,SLC20A1,SLC35A1,SLC25A33,SLC25A36 |
| 2.890e-02 | -3.54 | JOSEPH_RESPONSE_TO_SODIUM_BUTYRATE_UP | MSigDB lists | JOSEPH_RESPONSE_TO_SODIUM_BUTYRATE_UP | 30 | 9 | 17377 | 2626 |
SEC61B,RHOA,POLR2L,HADHB,PSAP,CLU,RAB11A,PRDX1,ESYT2 |
| 2.890e-02 | -3.54 | GO_POSITIVE_REGULATION_OF_INTERFERON_BETA_PRODUCTION | MSigDB lists | GO_POSITIVE_REGULATION_OF_INTERFERON_BETA_PRODUCTION | 30 | 9 | 17377 | 2626 |
DDX58,FLOT1,TICAM1,HMGB2,IRF3,MAVS,RNF135,IRF5,ZC3HAV1 |
| 2.892e-02 | -3.54 | human chr5p15.33 | chromosome location | human chr5p15.33 | 48 | 10 | 26185 | 2809 |
SLC12A7,EXOC3,PDCD6,PLEKHG4B,NKD2,BRD9,LPCAT1,SDHA,LRRC14B,CCDC127 |
| 2.893e-02 | -3.54 | DnaJ | pfam domains | PF00226 | 45 | 12 | 17054 | 2545 |
DNAJC2,DNAJC10,DNAJC8,DNAJC5,DNAJB2,DNAJC17,DNAJC24,DNAJC9,DNAJA1,DNAJB1,DNAJC30,DNAJB9 |
| 2.894e-02 | -3.54 | Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template | REACTOME pathways | R-HSA-110313 | 41 | 12 | 10287 | 1696 |
RPA2,PCNA,RFC3,POLE,POLK,RPS27A,USP10,RFC2,MAD2L2,NPLOC4,ISG15,RPA1 |
| 2.897e-02 | -3.54 | TFs Regulate miRNAs related to cardiac hypertrophy | WikiPathways | WP1559 | 12 | 5 | 5312 | 837 |
TGFB1,STAT3,AKT2,MYEF2,PPP3R1 |
| 2.897e-02 | -3.54 | RalA downstream regulated genes | WikiPathways | WP2290 | 12 | 5 | 5312 | 837 |
KRAS,NRAS,CDC42,HRAS,RAC1 |
| 2.897e-02 | -3.54 | oxidoreductase activity, acting on a heme group of donors | molecular function | GO:0016675 | 25 | 8 | 17224 | 2647 |
COX5B,COX15,COX7A2L,COX8A,COX5A,COX4I1,NDUFA4,CYB5A |
| 2.901e-02 | -3.54 | SEPHS1 (selenophosphate synthetase 1) | protein interactions | 22929 | 51 | 14 | 17029 | 2761 |
MAT2B,CRKL,PTPRF,CLIC4,GART,CDCA4,PDCD6,RTCB,TUFM,CUL3,MCFD2,XPO7,AHCYL1,ECH1 |
| 2.901e-02 | -3.54 | MAP2 (microtubule associated protein 2) | protein interactions | 4133 | 51 | 14 | 17029 | 2761 |
EIF3K,PA2G4,MDM2,PSMD8,RAE1,DHX9,YBX1,ACTB,PLEC,PRKACA,ABCF1,APP,DCTN1,RPL23A |
| 2.901e-02 | -3.54 | TAGLN (transgelin) | protein interactions | 6876 | 51 | 14 | 17029 | 2761 |
SUGP1,FKBP1A,PPIB,SARNP,HINT1,JAK1,NDUFA7,NUTF2,FKBP2,RNF14,POT1,CFL1,ISG15,GPX4 |
| 2.901e-02 | -3.54 | TNFSF13B (TNF superfamily member 13b) | protein interactions | 10673 | 51 | 14 | 17029 | 2761 |
NF1,TMEM39A,IMPAD1,PIGQ,BTAF1,ITGB1,TNPO2,TTC17,MAP3K5,NCAPG,ARSK,NUP85,APP,TMEM131 |
| 2.901e-02 | -3.54 | BUB1 (BUB1 mitotic checkpoint serine/threonine kinase) | protein interactions | 699 | 51 | 14 | 17029 | 2761 |
PLK1,CDKN2AIP,CDC16,DSN1,HPS5,RAE1,AP2B1,NUF2,PLEC,AP1B1,CDK2,MIS12,SEH1L,CDC5L |
| 2.901e-02 | -3.54 | ZCCHC10 (zinc finger CCHC-type containing 10) | protein interactions | 54819 | 51 | 14 | 17029 | 2761 |
SART1,CTNNBL1,SIAH1,PPIG,PIN1,DHX8,ARGLU1,PRPF3,CEP63,PCBP1,COIL,LUC7L2,EPB41,SF3B2 |
| 2.901e-02 | -3.54 | ULK1 (unc-51 like autophagy activating kinase 1) | protein interactions | 8408 | 51 | 14 | 17029 | 2761 |
PRKAB1,RALB,RB1CC1,PRKAA1,USP10,ATG13,IRF3,RAB1A,MAP1LC3B,BECN1,BIRC2,DAPK3,MLST8,CDC37 |
| 2.901e-02 | -3.54 | SCO2 (SCO2, cytochrome c oxidase assembly protein) | protein interactions | 9997 | 51 | 14 | 17029 | 2761 |
SUGP1,PPIB,SEPT9,MTMR4,PQBP1,CUL3,NDUFA4,MTMR12,NDUFA7,UBE4B,SPR,TUBGCP2,APP,PHKG2 |
| 2.902e-02 | -3.54 | PP2Ac | smart domains | SM00156 | 13 | 5 | 9493 | 1367 |
PPP2CA,PPP3CA,PPP3CB,PPP5C,PPP6C |
| 2.905e-02 | -3.54 | FORTSCHEGGER_PHF8_TARGETS_UP | MSigDB lists | FORTSCHEGGER_PHF8_TARGETS_UP | 243 | 48 | 17377 | 2626 |
ZNF76,MRPL42,NQO1,IVNS1ABP,SUZ12,CERK,XIAP,TOP2B,ZNF267,EIF2AK4,RCOR3,JMY,PABPC4,MAN1A1,MAT2B,FKBP1A,PTPN2,LIN9,RAB8A,NSRP1,ARL6IP1,FAM86C1,CITED2,EIF5,TPCN1,MGAT5,FAM171A1,RNLS,MND1,TCTEX1D2,NQO2,NLN,ZP3,SERP1,PDHX,ANKRD46,SERF1B,MTHFD2,SYNCRIP,CCDC6,KLHL15,PIAS2,SLC16A1,HMGB2,CNOT6,CLN3,LRP8,FUBP1 |
| 2.905e-02 | -3.54 | PLEC (plectin) | protein interactions | 5339 | 126 | 29 | 17029 | 2761 |
MAPRE1,CYLD,LUZP1,SUZ12,TKT,CUL3,MYH9,BRCA1,SMC2,CAPZA2,MCM2,ANLN,NCAPG,ETS1,SLTM,ISG15,DDX17,AHNAK,PTEN,QARS,MYO18A,SOCS6,USP20,CDK2,GNAI2,SMC4,CDC5L,SPTAN1,NIPSNAP1 |
| 2.910e-02 | -3.54 | kinase regulator activity | molecular function | GO:0019207 | 222 | 45 | 17224 | 2647 |
BCCIP,CCNC,FGFR1OP,GMFG,DBF4,CIB1,LAMTOR3,CCNL2,CCNB1,DAZAP2,CALM2,CDKN2C,CCNK,PIK3R2,SOCS6,DUS2,H2AFY,CDKN1B,ATG13,ABI1,MLST8,SOCS5,CHP1,CDC37,TGFB1,NCK1,TAOK1,GMFB,PRKAR1B,ELP4,WDR81,MARK2,MAP2K2,SOCS7,SH3BP5,MBIP,QARS,SOCS4,RPLP1,CAB39,STK11,WDR91,FAF1,CDKN2A,ALS2 |
| 2.920e-02 | -3.53 | REACTOME_METABOLISM_OF_NUCLEOTIDES | MSigDB lists | REACTOME_METABOLISM_OF_NUCLEOTIDES | 70 | 17 | 17377 | 2626 |
AMPD2,TK1,TXN,GUK1,UCK2,RRM1,RRM2,ADSL,UCK1,DCTD,CAT,ADSS,GART,DUT,ATIC,DCK,IMPDH1 |
| 2.922e-02 | -3.53 | GSE17721_LPS_VS_CPG_1H_BMDC_DN | MSigDB lists | GSE17721_LPS_VS_CPG_1H_BMDC_DN | 197 | 40 | 17377 | 2626 |
ZNF207,PRPF38B,SLC41A1,SF3B1,MECP2,DLGAP4,CHIC2,ABCB10,RBM4,BIRC2,RGS1,SLC25A37,CHKA,RAB21,MDM2,CLIC4,RCSD1,RNF19A,GCC1,ABCC5,CPNE1,STAU1,RFFL,PFKFB3,CYFIP2,HSPA1B,ADSS,UBTF,HLA-B,FBXO21,CDC27,BRD2,ITGB1,ZNF436,NUP62,FAM126A,SAMD8,NDE1,CBX4,S100PBP |
| 2.923e-02 | -3.53 | ubiquitin-like protein conjugating enzyme binding | molecular function | GO:0044390 | 39 | 11 | 17224 | 2647 |
LONRF3,SIAH2,DCUN1D5,RNF19A,DCUN1D4,TOLLIP,RNF14,ANKIB1,PARK7,RNF5,RNF114 |
| 2.923e-02 | -3.53 | Cori Cycle | WikiPathways | WP1946 | 16 | 6 | 5312 | 837 |
GPI,TALDO1,PGAM1,SLC2A1,PFKP,LDHA |
| 2.931e-02 | -3.53 | AAACCAC,MIR-140 | MSigDB lists | AAACCAC,MIR-140 | 102 | 23 | 17377 | 2626 |
TSHZ1,PHF20L1,ZBTB10,ETV3,SNX2,E2F3,CUL3,CTCF,NUTF2,SOX4,DCUN1D4,API5,DHX57,MEX3C,CSK,SIAH1,HNRNPH3,OGT,ADAM9,RNF19A,SENP1,EYA2,CSNK1G3 |
| 2.932e-02 | -3.53 | FoxO family signaling | Pathway Interaction DB | foxopathway | 48 | 15 | 2226 | 426 |
USP7,CAT,PLK1,CSNK1G2,CSNK1G1,CDKN1B,YWHAZ,CCNB1,YWHAH,CSNK1A1,ZFAND5,CDK2,FOXO3,CSNK1D,CSNK1G3 |
| 2.938e-02 | -3.53 | Vif-mediated degradation of APOBEC3G | REACTOME pathways | R-HSA-180585 | 55 | 15 | 10287 | 1696 |
PSMD2,PSMD1,PSMA6,PSMA8,RBX1,RPS27A,PSMD8,PSMD3,PSMB7,PSMA1,PSMB9,PSMD9,PSMC1,PSMB3,PSMC4 |
| 2.941e-02 | -3.53 | protein-DNA complex | cellular component | GO:0032993 | 195 | 39 | 18223 | 2701 |
POLA2,MAX,H2AFZ,MPHOSPH8,SHPRH,SUZ12,EYA1,TERF2IP,RPA2,IRF4,PCNA,XPA,H2AFY,ORC3,TERF2,PRPF19,CDC5L,HP1BP3,SP3,GINS1,PRIM2,PRKDC,HELB,WDR18,KDM1B,H2AFV,GINS4,PRIM1,XRCC5,RPA1,HHEX,TONSL,H2AFX,CENPT,H3F3A,SLF1,TERF1,PURA,POT1 |
| 2.942e-02 | -3.53 | G_TR_2 | prosite domains | PS51722 | 18 | 6 | 12060 | 1670 |
EFL1,GUF1,GFM2,EFTUD2,GSPT2,TUFM |
| 2.942e-02 | -3.53 | GNB2 (G protein subunit beta 2) | protein interactions | 2783 | 147 | 33 | 17029 | 2761 |
NDUFS1,RHOC,RAF1,MYH9,MEF2A,CDK13,SLC29A1,CSNK1A1,PCBP1,GRK2,TARDBP,GNAI2,ATF2,STAT3,ATP6V0D1,ASB6,EIF3L,CCT2,FAM118B,RAB7A,GNG7,NFATC2,ADRB2,GALK2,GNAS,PFDN5,PFDN4,STAT1,CLU,CDK2,ACSF2,EYA2,DDB1 |
| 2.942e-02 | -3.53 | CCDC85B (coiled-coil domain containing 85B) | protein interactions | 11007 | 147 | 33 | 17029 | 2761 |
NDUFA5,SKA3,FAM208B,MCM10,C19orf25,NUP54,MEAF6,MOAP1,CCNK,NEK6,PRC1,TP53BP2,MOB1A,RPL22L1,GCC1,MOB4,AGGF1,POLR2L,TSPYL4,PBXIP1,PSMA1,FAM50B,PRPF3,EIF3H,PLEKHF2,CHCHD3,MBIP,PLOD3,PSMC1,SSSCA1,ZNF564,CWC25,SMARCD1 |
| 2.943e-02 | -3.53 | V$HSF1_01 | MSigDB lists | V$HSF1_01 | 249 | 49 | 17377 | 2626 |
RORB,HSPH1,UBE2E2,CYLD,H2AFZ,ST13,PLXNC1,TRERF1,LUZP1,CCM2,AGPAT1,LAMTOR3,JMJD6,XPNPEP3,DNAJB1,MAPK14,CHD1,BCAP31,CREM,ANKRD28,HNRNPA2B1,NFATC3,NEK6,TNPO3,ABCD1,ATG13,KNTC1,PIKFYVE,EIF5,RNF5,ABCC5,SOCS5,ELOVL5,LAP3,DENND1B,TLK1,E2F3,KCNQ1,CADM1,DNAJA1,GIGYF1,PHF6,KRIT1,CBX3,ALKBH6,ZNF777,TAB2,DBI,SMAD1 |
| 2.945e-02 | -3.52 | GSE11924_TFH_VS_TH2_CD4_TCELL_DN | MSigDB lists | GSE11924_TFH_VS_TH2_CD4_TCELL_DN | 180 | 37 | 17377 | 2626 |
DNAJC2,MCM10,TRIP10,RAE1,GNE,UCK2,GTF3A,GGA2,PITHD1,HAUS2,PARK7,PABPC4,MOAP1,UBA5,MECR,NSFL1C,CS,TMBIM1,TMED2,ACSL5,PPAN,GALC,RAD51AP1,MRS2,GTPBP4,RPL6,MRPL12,CCT8,BBS12,TMEM168,ADAM9,TMEM219,WDR76,PGAM1,SSSCA1,VPS29,FAM72A |
| 2.949e-02 | -3.52 | DNA replication initiation | REACTOME pathways | R-HSA-68952 | 8 | 4 | 10287 | 1696 |
POLA2,POLE,PRIM2,PRIM1 |
| 2.949e-02 | -3.52 | Telomere C-strand synthesis initiation | REACTOME pathways | R-HSA-174430 | 8 | 4 | 10287 | 1696 |
POLA2,POLE,PRIM2,PRIM1 |
| 2.953e-02 | -3.52 | S1 | smart domains | SM00316 | 9 | 4 | 9493 | 1367 |
DHX8,POLR2G,PDCD11,EXOSC1 |
| 2.953e-02 | -3.52 | Alpha_adaptinC2 | smart domains | SM00809 | 9 | 4 | 9493 | 1367 |
AP2B1,AP1B1,GGA2,GGA1 |
| 2.953e-02 | -3.52 | VHS | smart domains | SM00288 | 9 | 4 | 9493 | 1367 |
HGS,GGA2,GGA1,STAM |
| 2.954e-02 | -3.52 | MAPK Cascade | WikiPathways | WP422 | 29 | 9 | 5312 | 837 |
NRAS,RAF1,KRAS,ELK1,MAPK14,MAPK1,MAP2K2,HRAS,MAPK3 |
| 2.954e-02 | -3.52 | GO_POSITIVE_REGULATION_OF_INTRACELLULAR_TRANSPORT | MSigDB lists | GO_POSITIVE_REGULATION_OF_INTRACELLULAR_TRANSPORT | 343 | 65 | 17377 | 2626 |
DDX58,UBE2D3,ZBED3,CHERP,ZDHHC8,DYNLL1,ANK3,CIB1,STARD7,PLAGL2,PPP3CB,ARF1,MAPK14,PRKACA,BCAP31,CALM2,CDK5,RAB21,MDM2,CDC42,HUWE1,SIVA1,PIK3R2,SRI,GTSE1,BCL2,ATG13,MAVS,CYB5R1,TP53BP2,F2R,HTRA2,PDPK1,PLK3,BAK1,TGFB1,PPP3CA,RHOA,KAT2A,AKT2,ACSL3,PSMB7,EZR,BRCA1,NUTF2,EDEM2,TRIM28,USP36,SH3GLB1,PCM1,KPNA1,PSMD8,STX18,TFDP1,OAZ2,PPP3R1,E2F1,PKD2,ZNF268,YWHAZ,RUFY3,YWHAH,SMAD4,OAZ1,SNAPIN |
| 2.959e-02 | -3.52 | Signaling by FGFR | REACTOME pathways | R-HSA-190236 | 89 | 22 | 10287 | 1696 |
POLR2I,NRAS,POLR2G,POLR2L,POLR2K,POLR2D,HNRNPF,TIA1,KRAS,POLR2A,MAPK3,GTF2F1,PPP2CA,FGFR3,MKNK1,SHC1,POLR2J,RPS27A,PTPN11,MAPK1,HRAS,HNRNPM |
| 2.974e-02 | -3.52 | BIOCARTA_TFF_PATHWAY | MSigDB lists | BIOCARTA_TFF_PATHWAY | 21 | 7 | 17377 | 2626 |
CYCS,RHOA,SHC1,MAPK1,HRAS,MAPK3,ITGB1 |
| 2.974e-02 | -3.52 | GO_U4_U6_X_U5_TRI_SNRNP_COMPLEX | MSigDB lists | GO_U4_U6_X_U5_TRI_SNRNP_COMPLEX | 21 | 7 | 17377 | 2626 |
SART1,PRPF4,PRPF3,TXNL4A,LSM6,SNRPB,PRPF18 |
| 2.974e-02 | -3.52 | GO_REGULATION_OF_TELOMERE_CAPPING | MSigDB lists | GO_REGULATION_OF_TELOMERE_CAPPING | 21 | 7 | 17377 | 2626 |
MAP3K4,USP7,AURKB,MAPK1,NEK7,MAPK3,TERF2 |
| 2.974e-02 | -3.52 | VIETOR_IFRD1_TARGETS | MSigDB lists | VIETOR_IFRD1_TARGETS | 21 | 7 | 17377 | 2626 |
ANP32E,TK1,RPL17,UQCR10,RPL22L1,PTTG1,EBP |
| 2.974e-02 | -3.52 | WU_HBX_TARGETS_1_DN | MSigDB lists | WU_HBX_TARGETS_1_DN | 21 | 7 | 17377 | 2626 |
TGFB1,CSNK1G2,BCL2L1,PPP5C,KLF6,PDS5B,RYBP |
| 2.974e-02 | -3.52 | FOURNIER_ACINAR_DEVELOPMENT_LATE_DN | MSigDB lists | FOURNIER_ACINAR_DEVELOPMENT_LATE_DN | 21 | 7 | 17377 | 2626 |
RRM2,ACTB,FOXM1,NCAPG,ODC1,ASPM,CEP55 |
| 2.974e-02 | -3.52 | GO_NECROPTOTIC_PROCESS | MSigDB lists | GO_NECROPTOTIC_PROCESS | 21 | 7 | 17377 | 2626 |
PPIF,TICAM1,SIRT2,CYLD,BIRC2,FADD,FAS |
| 2.974e-02 | -3.52 | REACTOME_DOWNREGULATION_OF_TGF_BETA_RECEPTOR_SIGNALING | MSigDB lists | REACTOME_DOWNREGULATION_OF_TGF_BETA_RECEPTOR_SIGNALING | 21 | 7 | 17377 | 2626 |
TGFB1,SMAD2,SMURF1,MTMR4,RPS27A,UCHL5,STRAP |
| 2.974e-02 | -3.52 | BIOCARTA_IGF1_PATHWAY | MSigDB lists | BIOCARTA_IGF1_PATHWAY | 21 | 7 | 17377 | 2626 |
CSNK2A1,SHC1,ELK1,HRAS,RAF1,MAPK3,PTPN11 |
| 2.974e-02 | -3.52 | IIZUKA_LIVER_CANCER_PROGRESSION_L0_L1_DN | MSigDB lists | IIZUKA_LIVER_CANCER_PROGRESSION_L0_L1_DN | 21 | 7 | 17377 | 2626 |
SRP72,COX4I1,KARS,CTSA,RHOA,HLA-A,TMX1 |
| 2.976e-02 | -3.51 | human chr9q34.11 | chromosome location | human chr9q34.11 | 83 | 15 | 26185 | 2809 |
C9orf78,NUP188,COQ4,GOLGA2,CRAT,ODF2,SH3GLB2,USP20,LRRC8A,SLC27A4,TBC1D13,GLE1,ASB6,SPTAN1,ZER1 |
| 2.976e-02 | -3.51 | chr16p11 | MSigDB lists | chr16p11 | 86 | 20 | 17377 | 2626 |
SEPHS2,ZNF768,TUFM,NFATC2IP,ZNF267,INO80E,VKORC1,IL21R,MAPK3,FBRS,ZNF689,ATXN2L,BCL7C,TMEM219,KIF22,CORO1A,MVP,FBXL19,PHKG2,ZNF720 |
| 2.976e-02 | -3.51 | KEGG_APOPTOSIS | MSigDB lists | KEGG_APOPTOSIS | 86 | 20 | 17377 | 2626 |
PPP3CA,BIRC3,CASP6,AKT2,PRKAR1B,XIAP,CYCS,BCL2L1,PPP3CB,PRKACA,BIRC2,FADD,FAS,CFLAR,CAPN2,PIK3R2,PPP3R1,BCL2,MAP3K14,CAPN1 |
| 2.984e-02 | -3.51 | positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway | biological process | GO:1900740 | 30 | 9 | 17256 | 2622 |
DYNLL1,TFDP1,E2F1,PPP3R1,YWHAZ,BCL2,TP53BP2,TFDP2,YWHAH |
| 2.984e-02 | -3.51 | somatic diversification of immunoglobulins | biological process | GO:0016445 | 30 | 9 | 17256 | 2622 |
ERCC1,EXOSC6,CTNNBL1,PRKDC,TCF3,PMS2,MSH2,MSH6,POLQ |
| 2.984e-02 | -3.51 | positive regulation of interferon-beta production | biological process | GO:0032728 | 30 | 9 | 17256 | 2622 |
DDX58,DHX9,FLOT1,HMGB2,TICAM1,MAVS,IRF3,RNF135,IRF5 |
| 2.984e-02 | -3.51 | extrinsic apoptotic signaling pathway in absence of ligand | biological process | GO:0097192 | 30 | 9 | 17256 | 2622 |
MOAP1,BAK1,BCL2,MCL1,BCL2L1,FOXO3,EYA2,APPL1,FADD |
| 2.984e-02 | -3.51 | regulation of double-strand break repair via homologous recombination | biological process | GO:0010569 | 30 | 9 | 17256 | 2622 |
TERF2IP,RPA2,KLHL15,RAD51AP1,HELB,PARPBP,MRNIP,SPIDR,POLQ |
| 2.984e-02 | -3.51 | negative regulation of mRNA processing | biological process | GO:0050686 | 30 | 9 | 17256 | 2622 |
HNRNPA2B1,RBM42,RBMX,SRSF6,SRSF4,RNPS1,CTR9,TRA2B,SRSF10 |
| 2.984e-02 | -3.51 | signal transduction in absence of ligand | biological process | GO:0038034 | 30 | 9 | 17256 | 2622 |
MOAP1,BAK1,BCL2,MCL1,BCL2L1,FOXO3,EYA2,APPL1,FADD |
| 2.984e-02 | -3.51 | regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway | biological process | GO:1900739 | 30 | 9 | 17256 | 2622 |
DYNLL1,TFDP1,E2F1,PPP3R1,YWHAZ,BCL2,TP53BP2,TFDP2,YWHAH |
| 2.986e-02 | -3.51 | HDL cholesterol(PMID:19060906) | GWAS genes | HDL cholesterol(PMID:19060906) | 10 | 4 | 2388 | 307 |
GALNT2,NUTF2,RAB11B,ABCA1 |
| 2.998e-02 | -3.51 | AGGAGTG,MIR-483 | MSigDB lists | AGGAGTG,MIR-483 | 65 | 16 | 17377 | 2626 |
VEZF1,PHF20L1,WDR44,RB1CC1,MTA2,ODF2,OGT,RBM3,PLXNA1,MXD4,SRSF5,H3F3A,PDCD7,DNAL4,CAMK2G,SRSF1 |
| 2.998e-02 | -3.51 | GTTAAAG,MIR-302B | MSigDB lists | GTTAAAG,MIR-302B | 65 | 16 | 17377 | 2626 |
POU3F2,RAB14,GGNBP2,MLEC,TRAF7,ATP2C1,PLAGL2,ATXN1,LCLAT1,PDK2,ARNTL,DDA1,AP1S1,ST8SIA2,TIPARP,CPEB2 |
| 2.998e-02 | -3.51 | MAPK6 (mitogen-activated protein kinase 6) | protein interactions | 5597 | 195 | 42 | 17029 | 2761 |
PRKAB1,NAT9,PDCD6IP,CASP6,GORASP1,ANK3,DCTN2,KLC1,ATP5PF,GLRX3,SLC20A1,FOXO3,HAUS2,SNAPC4,ZNF92,PHC2,DST,SHC1,THAP4,OSTF1,CFL1,SPTAN1,ELOF1,PLK1,FAM49B,ATG9A,METTL2A,MYBL2,SRSF5,GALNT7,EDF1,MBIP,VPS26C,PDLIM1,DDOST,RBL1,HNRNPH3,MAPK6,NAXE,USP20,COPS6,IDH3B |
| 3.000e-02 | -3.51 | Nucleotide excision repair | KEGG pathways | ko03420 | 47 | 13 | 7161 | 1149 |
RPA2,ERCC1,RFC3,PCNA,POLE,RBX1,XPA,RAD23B,GTF2H2,RFC2,DDB1,RPA1,RAD23A |
| 3.000e-02 | -3.51 | Nucleotide excision repair | KEGG pathways | hsa03420 | 47 | 13 | 7161 | 1149 |
RPA2,ERCC1,PCNA,RFC3,POLE,RBX1,XPA,RAD23B,RFC2,GTF2H2,DDB1,RAD23A,RPA1 |
| 3.000e-02 | -3.51 | Hedgehog signaling pathway | KEGG pathways | hsa04340 | 47 | 13 | 7161 | 1149 |
CSNK1G2,GRK2,CSNK1G1,CUL3,CUL1,BCL2,CSNK1A1,SMURF1,ARRB2,PRKACA,CSNK1D,CSNK1G3,EVC2 |
| 3.000e-02 | -3.51 | Hedgehog signaling pathway | KEGG pathways | ko04340 | 47 | 13 | 7161 | 1149 |
CSNK1G2,GRK2,CSNK1G1,CUL3,CUL1,BCL2,CSNK1A1,SMURF1,ARRB2,PRKACA,CSNK1D,CSNK1G3,EVC2 |
| 3.005e-02 | -3.50 | GO_ISOMERASE_ACTIVITY | MSigDB lists | GO_ISOMERASE_ACTIVITY | 152 | 32 | 17377 | 2626 |
MIF,PPIB,MUT,GNPDA1,MRI1,GNE,TMX4,TMX3,TOP2B,FKBP2,QSOX2,EBP,FKBP1A,CWC27,PIN1,PPIG,PPIL2,TTC9C,PTGES3,TOP1MT,PDIA6,TMX1,PPIF,TSTA3,PPIE,TOP3A,PPWD1,FKBP3,ECH1,FKBP5,GPI,PGAM1 |
| 3.005e-02 | -3.50 | GO_POSITIVE_REGULATION_OF_MITOCHONDRION_ORGANIZATION | MSigDB lists | GO_POSITIVE_REGULATION_OF_MITOCHONDRION_ORGANIZATION | 152 | 32 | 17377 | 2626 |
UBE2D3,ZBED3,BAK1,PPIF,KAT2A,ZDHHC8,DYNLL1,PSMB7,STARD7,PLAGL2,ADRB2,BECN1,PARK7,APOPT1,USP36,SH3GLB1,STOML2,MOAP1,HUWE1,PSMD8,SIVA1,TFDP1,E2F1,PPP3R1,ATG13,BCL2,YWHAZ,CYB5R1,TP53BP2,YWHAH,NSUN4,HTRA2 |
| 3.005e-02 | -3.50 | TAATGTG,MIR-323 | MSigDB lists | TAATGTG,MIR-323 | 152 | 32 | 17377 | 2626 |
UBL3,ANKRD27,TMED7,CLCN3,PKP4,MAPRE1,C16orf72,BTAF1,MAP4K4,WBP2,CUL1,TOP2B,ARGLU1,MCFD2,RAB1A,BORA,LCLAT1,QSOX2,FANCI,SRSF1,KPNA1,PDCD10,CCDC6,VPS26B,ZHX1,TBPL1,UHRF2,CDKN1B,FEM1B,PITPNA,CREB1,CSNK1G3 |
| 3.005e-02 | -3.50 | chr17q25 | MSigDB lists | chr17q25 | 152 | 32 | 17377 | 2626 |
UNK,NAT9,MIF4GD,SUMO2,JMJD6,TRIM65,EIF4A3,SLC38A10,PCYT2,NUP85,CCDC57,CYTH1,TIMP2,SEPT9,PGS1,NARF,RPL38,WBP2,MRPL12,USP36,RHBDF2,TRIM47,SGSH,HGS,BIRC5,CANT1,SLC25A19,FN3KRP,H3F3A,CSNK1D,CBX4,CCDC137 |
| 3.007e-02 | -3.50 | aminoacyl-tRNA ligase activity | molecular function | GO:0004812 | 44 | 12 | 17224 | 2647 |
FARSA,KARS,EPRS,LARS,IARS,HARS,MRPL39,QARS,IARS2,POLG2,TARS,CARS2 |
| 3.007e-02 | -3.50 | ligase activity, forming carbon-oxygen bonds | molecular function | GO:0016875 | 44 | 12 | 17224 | 2647 |
FARSA,KARS,EPRS,LARS,IARS,HARS,MRPL39,QARS,IARS2,POLG2,TARS,CARS2 |
| 3.009e-02 | -3.50 | UBAP2L (ubiquitin associated protein 2 like) | protein interactions | 9898 | 56 | 15 | 17029 | 2761 |
KAT2A,PTEN,PRRC2A,SF3B1,MED15,CUL3,ACAT1,ATXN1,YBX1,BRCA1,FUS,ZP3,ANLN,HNRNPDL,ISG15 |
| 3.009e-02 | -3.50 | MED10 (mediator complex subunit 10) | protein interactions | 84246 | 56 | 15 | 17029 | 2761 |
MOB4,CCNC,NAP1L1,POLR2I,MED8,POLR2G,POLR2L,POLR2J,BIRC5,POLR2K,MED15,POLR2D,MED13L,MED22,POLR2A |
| 3.009e-02 | -3.50 | SLC18A1 (solute carrier family 18 member A1) | protein interactions | 6570 | 56 | 15 | 17029 | 2761 |
MTX3,ARF5,BDH1,SDC2,ANKRD13C,PXMP2,SLC29A1,SLC12A9,NR2F2,NDUFA3,ECPAS,FAM8A1,SFXN5,PDXDC1,TYW1B |
| 3.009e-02 | -3.50 | MED6 (mediator complex subunit 6) | protein interactions | 10001 | 56 | 15 | 17029 | 2761 |
CCNC,CTDP1,SMAD2,MED8,MED10,POLR2G,BIRC5,SUZ12,MED15,KIF15,MED13L,CUL1,SMARCA4,TARDBP,SMAD1 |
| 3.009e-02 | -3.50 | GRIPAP1 (GRIP1 associated protein 1) | protein interactions | 56850 | 56 | 15 | 17029 | 2761 |
OIP5,CCDC93,MAX,RPRD1A,SMAD2,GRIPAP1,RABGAP1L,ARNTL,RAB4A,RCOR1,NUF2,PSMD9,SMURF1,GIT2,HMG20A |
| 3.009e-02 | -3.50 | PNO1 (partner of NOB1 homolog) | protein interactions | 56902 | 56 | 15 | 17029 | 2761 |
PTPN2,PDPK1,MTMR3,RB1,NSUN2,RPS24,FAU,FBL,KLF6,RPS26,KCMF1,RPS9,RPSA,BYSL,CAND1 |
| 3.009e-02 | -3.50 | ARNT (aryl hydrocarbon receptor nuclear translocator) | protein interactions | 405 | 56 | 15 | 17029 | 2761 |
RB1,NCOR2,STRBP,DCAF15,PML,PIAS2,LSM8,CSNK2A1,BRCA1,NCOA1,PTGES3,CREB1,UBE2I,NCOA2,GTF2F1 |
| 3.011e-02 | -3.50 | repressing transcription factor binding | molecular function | GO:0070491 | 64 | 16 | 17224 | 2647 |
MTA2,TCF3,DDX20,PARK7,DDRGK1,HHEX,HDAC7,MTA1,ARNTL,SRI,STAT1,NOC2L,RBPJ,YY1,STAT3,HDAC2 |
| 3.014e-02 | -3.50 | lactate fermentation (reoxidation of cytosolic NADH) | BIOCYC pathways | HUMAN_PWY-5481 | 2 | 2 | 902 | 157 |
LDHA,LDHB |
| 3.014e-02 | -3.50 | superpathway of CMP-sialic acids biosynthesis | BIOCYC pathways | META_PWY-6145 | 2 | 2 | 902 | 157 |
NANS,NANP |
| 3.014e-02 | -3.50 | CMP-N-acetylneuraminate biosynthesis I (eukaryotes) | BIOCYC pathways | META_PWY-6138 | 2 | 2 | 902 | 157 |
NANS,NANP |
| 3.014e-02 | -3.50 | CMP-N-acetylneuraminate biosynthesis I (eukaryotes) | BIOCYC pathways | HUMAN_PWY-6138 | 2 | 2 | 902 | 157 |
CMAS,NANS |
| 3.015e-02 | -3.50 | eukaryotic translation initiation factor 3 complex | cellular component | GO:0005852 | 17 | 6 | 18223 | 2701 |
EIF3K,EIF3L,EIF3G,EIF3D,EIF3H,EIF3A |
| 3.016e-02 | -3.50 | GSE17721_PAM3CSK4_VS_CPG_1H_BMDC_DN | MSigDB lists | GSE17721_PAM3CSK4_VS_CPG_1H_BMDC_DN | 186 | 38 | 17377 | 2626 |
ZNF207,TSC22D3,DNAJB2,SCYL1,STRN4,RACGAP1,ABCB10,CHAC2,CSNK1A1,STMN1,BIRC2,KCMF1,LIN9,GOLM1,MDM2,DUT,ZC3H3,TMBIM1,TMEM39A,ANKRD33B,MKI67,PSMA1,RAB2B,RDH11,FAS,ADSS,MTHFD2,KPNA4,POLR2J,UAP1,RBM47,TBPL1,PGRMC1,BTBD10,NDE1,CDK2,PSMC1,CBX4 |
| 3.016e-02 | -3.50 | GSE4984_LPS_VS_VEHICLE_CTRL_TREATED_DC_DN | MSigDB lists | GSE4984_LPS_VS_VEHICLE_CTRL_TREATED_DC_DN | 186 | 38 | 17377 | 2626 |
TMEM106C,WSB2,TRERF1,NF1,UBR2,MECP2,FAM129A,TMX4,NCKAP1,GGA2,PPP1R16B,CFLAR,RB1,SLC1A4,NEK6,ZNF335,PRC1,FAM89B,RNF19A,SGCB,TNRC18,CNNM3,NCOA2,MYO5A,MICAL3,SNRNP200,TNFAIP3,TMEM39A,EMB,ATXN1,NFATC2,IL12RB1,OGDH,PICALM,RHBDF2,CORO1C,ADAM9,MBOAT1 |
| 3.016e-02 | -3.50 | GSE8921_UNSTIM_VS_TLR1_2_STIM_MONOCYTE_3H_UP | MSigDB lists | GSE8921_UNSTIM_VS_TLR1_2_STIM_MONOCYTE_3H_UP | 186 | 38 | 17377 | 2626 |
HNRNPAB,FLYWCH2,MRPL39,USP39,KIF2C,NANS,NCAPG,NDUFS7,TMCC3,KIFC1,OIP5,LYAR,DDX56,DUT,LPIN2,ARL6IP1,GEMIN6,GLE1,SLC35C2,C12orf75,DNMT1,NUP85,EIF3L,TIMM8B,TK1,LAP3,TMEM39A,RAD51AP1,CKAP2L,WDHD1,NUP155,RAB3IP,RAD54B,HSPBP1,LRPPRC,WDR76,PDSS2,SAT2 |
| 3.016e-02 | -3.50 | GSE22196_HEALTHY_VS_OBESE_MOUSE_SKIN_GAMMADELTA_TCELL_UP | MSigDB lists | GSE22196_HEALTHY_VS_OBESE_MOUSE_SKIN_GAMMADELTA_TCELL_UP | 186 | 38 | 17377 | 2626 |
SEPHS2,SCAMP3,TRIO,TMEM109,TAP1,CUL1,SLC20A1,SDHA,PTPN2,GNS,DECR1,ATIC,TAP2,PHKG2,GM2A,TERF2,VPS13B,KDM3B,TRAFD1,ERLIN1,FRAT2,GALK2,PSMB9,PSMB3,ECH1,ABHD5,SDHB,NUCB1,CERS6,CSK,BBX,OGT,ARAP1,WDR7,PML,CLU,CHEK2,ZBTB11 |
| 3.016e-02 | -3.50 | GSE22432_UNTREATED_VS_TGFB1_TREATED_COMMON_DC_PROGENITOR_UP | MSigDB lists | GSE22432_UNTREATED_VS_TGFB1_TREATED_COMMON_DC_PROGENITOR_UP | 186 | 38 | 17377 | 2626 |
DDX58,TRIM41,DNMT3A,GOLPH3L,TMBIM4,GORASP1,PTTG1,SUMF1,RAB11A,ANKRD23,RGS1,NSRP1,THAP4,DPYSL2,FBXO7,RRBP1,TAF5L,ASB6,SPSB3,ENPP4,ACP2,FOXK1,HPDL,SELPLG,LYRM1,TMEM216,UTP3,EAF2,IL12RB1,SYMPK,DAPK3,PWWP2B,SCARB2,STX18,APPL2,SLC25A19,WIPI2,TSTD2 |
| 3.016e-02 | -3.50 | GSE40666_UNTREATED_VS_IFNA_STIM_STAT4_KO_EFFECTOR_CD8_TCELL_90MIN_UP | MSigDB lists | GSE40666_UNTREATED_VS_IFNA_STIM_STAT4_KO_EFFECTOR_CD8_TCELL_90MIN_UP | 186 | 38 | 17377 | 2626 |
SRM,RHOG,IER2,CORO7,TRERF1,HJURP,CUTA,TAP1,ARID5A,NANS,ARF1,SND1,GSTK1,DPYSL2,TAGLN2,C12orf75,VOPP1,BAK1,CYFIP1,SEC61B,MAPKAPK3,ASPM,OGDH,IRF5,PI4K2A,MYO1F,TFEB,TRAM2,TRIM47,KEAP1,STK38,HIPK2,TFDP1,NLRC5,KPNA2,ASNA1,YWHAH,AP2S1 |
| 3.016e-02 | -3.50 | GSE17721_PAM3CSK4_VS_GADIQUIMOD_4H_BMDC_UP | MSigDB lists | GSE17721_PAM3CSK4_VS_GADIQUIMOD_4H_BMDC_UP | 186 | 38 | 17377 | 2626 |
SEPHS2,SRM,CCDC93,DNMT3A,DHPS,TCF3,ALKBH5,UBE2Z,SIRT2,CDC42SE2,NCKAP1,WDR5,TWF2,PPP1R16B,MIS12,IRF4,GATC,BUD31,COPS7B,SPTAN1,AMPD2,FTL,POLR2I,CREG1,NSDHL,SMU1,PIP4K2C,ARHGEF12,SF3A2,CDCA4,HINT1,RBMX,UBXN2B,CDCA5,LY75,SAMD8,PGAM1,EYA2 |
| 3.016e-02 | -3.50 | GSE23308_CTRL_VS_CORTICOSTERONE_TREATED_MACROPHAGE_UP | MSigDB lists | GSE23308_CTRL_VS_CORTICOSTERONE_TREATED_MACROPHAGE_UP | 186 | 38 | 17377 | 2626 |
SLC41A1,ABCC10,SCYL1,ARFIP2,PDCD7,SLC12A9,CSNK1A1,IL21R,PIP4K2A,RPL23A,KRI1,VAV1,APLP2,SLC38A5,THAP4,RPL19,TMEM8A,MVP,TMEM14C,POC5,BRD4,NXT1,RPL35,AKT2,HEBP2,ATXN1,SREK1,LRP5,SYVN1,STYXL1,GFER,CCT8,ABCF1,ADAM9,SMPD4,SMAD1,NUDT3,DDX52 |
| 3.016e-02 | -3.50 | GSE3337_4H_VS_16H_IFNG_IN_CD8POS_DC_DN | MSigDB lists | GSE3337_4H_VS_16H_IFNG_IN_CD8POS_DC_DN | 186 | 38 | 17377 | 2626 |
MAGEH1,SYS1,GMFG,UCK1,EPN1,SUMF1,MAN2B1,MXD4,CDIPT,FERMT3,ARF5,PELO,ARL6IP1,KCNAB2,KDELR1,TMEM160,BAK1,PTPN18,SEPT9,ERF,EMB,NLN,MAP4K3,ZP3,ICAM2,LY6E,HAGH,SLC50A1,GEMIN5,NUCB1,ACOX1,CTSA,PSAP,MAP3K5,CLN3,PLOD3,HEXA,NUDT3 |
| 3.016e-02 | -3.50 | GSE34156_UNTREATED_VS_24H_NOD2_LIGAND_TREATED_MONOCYTE_DN | MSigDB lists | GSE34156_UNTREATED_VS_24H_NOD2_LIGAND_TREATED_MONOCYTE_DN | 186 | 38 | 17377 | 2626 |
SESTD1,RAC1,UBE2Z,ASAH1,ATP6V1B2,SLC25A37,TNS3,CLIC4,PDCD10,NDUFB4,BRI3,ANXA5,ARHGEF2,RP2,TALDO1,CNPY3,GM2A,SEH1L,WDR41,FTL,TIMP2,CREG1,RAB7A,ZBED5,MAP4K3,CAPZA2,METTL22,KDM1B,IRF5,TMEM127,ALDH3B1,RAD51C,RBM47,CORO1C,ADAM9,PITPNA,ABCA1,BYSL |
| 3.016e-02 | -3.50 | GSE41867_DAY8_VS_DAY15_LCMV_CLONE13_EFFECTOR_CD8_TCELL_UP | MSigDB lists | GSE41867_DAY8_VS_DAY15_LCMV_CLONE13_EFFECTOR_CD8_TCELL_UP | 186 | 38 | 17377 | 2626 |
PNISR,TRIM11,SRSF6,CDT1,ADPGK,DAZAP2,CDK11B,SAFB2,ETS1,SLC25A36,IL6ST,ZNF326,CDKN1B,RPL22L1,ADCY7,MOB4,CDKN2AIP,TACC1,RDH10,MTMR12,USP22,ADRB2,AZI2,HERPUD2,TSR2,BSDC1,KRIT1,LEMD2,MOSPD3,MTMR3,MKNK1,PCM1,RAD18,NSF,KLHL15,SIAH2,DVL1,ABCA1 |
| 3.016e-02 | -3.50 | GSE18893_TCONV_VS_TREG_2H_TNF_STIM_UP | MSigDB lists | GSE18893_TCONV_VS_TREG_2H_TNF_STIM_UP | 186 | 38 | 17377 | 2626 |
TMEM41B,PTTG1,STARD7,SECISBP2,AGFG1,COMMD5,SLC12A9,RPL23A,RAB35,BDH1,FJX1,PHTF1,AHDC1,MAVS,CABLES2,TOP1MT,MVP,SLC35C2,SGCB,GPD1L,ARL5A,USP34,NAGPA,TELO2,ERCC1,POLR2G,TSTA3,SCFD2,NUTF2,VKORC1,USP21,TRIM28,UEVLD,GADD45B,CEP55,PRPS2,LPCAT4,SLC16A1 |
| 3.016e-02 | -3.50 | GSE27786_ERYTHROBLAST_VS_NEUTROPHIL_UP | MSigDB lists | GSE27786_ERYTHROBLAST_VS_NEUTROPHIL_UP | 186 | 38 | 17377 | 2626 |
SKA3,ABCA3,C1orf112,UQCR10,GPR89A,TRIO,OLA1,PPP3CB,PRNP,SAP130,SNRNP25,CCNA2,STRBP,FNIP2,NUDC,NASP,DDX24,TLK1,FAM133B,BCLAF1,NUP155,OGDH,GSTCD,ANLN,LUC7L,NECAP2,DGCR8,LUC7L3,PTAR1,WDR7,ACBD4,WIPI2,SMPD4,SASS6,SSSCA1,B4GALT2,GPR89B,RAB3IL1 |
| 3.016e-02 | -3.50 | GSE14308_TH2_VS_INDUCED_TREG_UP | MSigDB lists | GSE14308_TH2_VS_INDUCED_TREG_UP | 186 | 38 | 17377 | 2626 |
TMEM203,SCYL1,PTTG1,OLA1,TIA1,SUMF1,GYG1,IFT27,FOXO3,TMEM161B,SRXN1,MDM2,ZNF260,EIF5,PLCL2,MTPN,PDLIM2,FTL,KLF10,ASPM,NEK7,MAP4K4,PCGF1,GOSR1,TAZ,ARPC1A,MASTL,JAK1,GOLGA7,AGPAT2,EXOC4,TBPL1,MEGF9,DDX5,PPP6R3,C11orf1,RPS26,PURA |
| 3.016e-02 | -3.50 | GSE33292_WT_VS_TCF1_KO_DN3_THYMOCYTE_UP | MSigDB lists | GSE33292_WT_VS_TCF1_KO_DN3_THYMOCYTE_UP | 186 | 38 | 17377 | 2626 |
UBL3,CTDP1,CYLD,GORASP1,RPS6KA1,HLA-E,GADD45G,HABP4,AGFG1,BCL2L1,EPHX2,PSEN1,FAM8A1,DNAJB9,MAN1A1,RIMS3,DAPK1,ABI1,ENPP4,MOB4,CYTH1,TNFAIP3,RB1CC1,BAZ2A,NEK7,MTMR6,SRSF5,SH3GLB1,OPTN,MTMR3,ZNF862,GALNT2,CTBS,SMAD1,RNF14,N4BP2L2,ADAM23,TMEM131 |
| 3.016e-02 | -3.50 | GSE13493_DP_VS_CD4INTCD8POS_THYMOCYTE_DN | MSigDB lists | GSE13493_DP_VS_CD4INTCD8POS_THYMOCYTE_DN | 186 | 38 | 17377 | 2626 |
INTS2,RPS2,NDUFS1,B4GALT5,SRGN,SMC6,EIF2AK4,CLUAP1,FGFR3,DECR1,RRBP1,EI24,GPATCH1,RPF2,YBX1,RBM15,PPA1,POU2AF1,KAT2A,GUK1,MAPKAPK3,PSMA8,TYW1,PPIE,RPL6,EMP3,EXOSC9,FOXRED1,CCT8,ABHD5,SDHB,C1orf131,UAP1,TONSL,ZC3H7B,MBOAT1,BTF3,MRPL3 |
| 3.016e-02 | -3.50 | GSE7400_CTRL_VS_CSF3_IN_VIVO_TREATED_PBMC_DN | MSigDB lists | GSE7400_CTRL_VS_CSF3_IN_VIVO_TREATED_PBMC_DN | 186 | 38 | 17377 | 2626 |
ADAM10,PRKAA1,DCTN2,MEF2A,SIRT2,GYG1,TWF2,AP3S1,PSMD9,APH1B,CUTC,RAB11A,GIT2,SPPL2A,C14orf119,CALM2,CD59,AP3S2,GLTP,MOB1A,FBXL19,RHBDD2,S100A6,CFL1,VOPP1,TIMM8B,PGS1,MKI67,LACTB,FBXO9,VKORC1,PEF1,MKNK1,KIF18B,CHCHD1,PRDX5,CAB39,SLC22A23 |
| 3.016e-02 | -3.50 | GSE8621_LPS_STIM_VS_LPS_PRIMED_AND_LPS_STIM_MACROPHAGE_DN | MSigDB lists | GSE8621_LPS_STIM_VS_LPS_PRIMED_AND_LPS_STIM_MACROPHAGE_DN | 186 | 38 | 17377 | 2626 |
TRIP12,DYNLL1,TRIO,HEXB,SLC29A1,SNN,ETS1,TCF19,REPS1,TFRC,UBLCP1,LIN9,RFWD3,LHX8,METTL14,IMPAD1,RCSD1,TIMELESS,ORAI1,IMPA2,SAP30,ASPM,EMB,DHX29,LRBA,DNAJC9,WIPF1,MAK16,EIF3G,MYO1F,MAP3K4,PFDN5,OSBPL11,KPNA4,TTC13,RAD18,AKNA,CCNB2 |
| 3.021e-02 | -3.50 | V$HNF4_01_B | MSigDB lists | V$HNF4_01_B | 232 | 46 | 17377 | 2626 |
TCF12,PTMS,HNRNPAB,PRKCSH,UQCR10,SRSF6,DCTN2,AGPAT1,GLUD1,TBC1D13,AP1B1,DOCK11,PRKACA,XPR1,CALM2,FAM192A,ZBTB45,NEK6,MTMR4,ETV6,SRSF4,FUT8,CRY2,GLTP,MRPL40,RPRD1B,RNF5,ACSL5,GCC2,MLEC,BAZ2A,AKT2,SLC26A6,WDR81,PICALM,MARK2,RHOB,TRIM47,GOLGA4,GALNT2,DUSP3,RBMS1,ACTB,NR2F2,ZSWIM3,REEP4 |
| 3.026e-02 | -3.50 | GSE9509_LPS_VS_LPS_AND_IL10_STIM_IL10_KO_MACROPHAGE_30MIN_DN | MSigDB lists | GSE9509_LPS_VS_LPS_AND_IL10_STIM_IL10_KO_MACROPHAGE_30MIN_DN | 169 | 35 | 17377 | 2626 |
POLA2,CLSPN,SESTD1,CDCA8,KIF23,MAP1LC3B,STMN1,STAM,FBXO5,MDM2,RIMS3,PDS5B,MDFIC,CDC25B,SMC4,SAP30,POU2AF1,SHOC2,PPP1R18,BTG2,MYBL2,CKAP2L,ANLN,CYFIP2,GINS4,SIAH2,NCLN,PKD2,UBE2C,CCNB2,E2F2,ESPL1,ABCA1,C7orf26,POLQ |
| 3.026e-02 | -3.50 | GSE17974_0H_VS_2H_IN_VITRO_ACT_CD4_TCELL_UP | MSigDB lists | GSE17974_0H_VS_2H_IN_VITRO_ACT_CD4_TCELL_UP | 169 | 35 | 17377 | 2626 |
ZBTB10,WDYHV1,WDR13,ABCC10,ACAP1,ASAH1,XPNPEP3,RGS2,SNN,EPHX2,ZADH2,RGS1,ANKRD39,GSTK1,GSDMB,TBC1D22A,RCSD1,SUCLG2,CITED2,S100A6,HEMK1,GALC,RFXANK,POLR3GL,TAZ,WAS,VPS26B,KLHL15,EIF2D,NFIL3,DTD1,ZMIZ1,RPS6KC1,TOB1,ZC3HAV1 |
| 3.026e-02 | -3.50 | GSE46242_TH1_VS_ANERGIC_TH1_CD4_TCELL_UP | MSigDB lists | GSE46242_TH1_VS_ANERGIC_TH1_CD4_TCELL_UP | 169 | 35 | 17377 | 2626 |
TMUB1,TP53RK,SRGN,UCK2,BRAP,DHX8,POMP,TWF2,EIF1B,MYL6B,NPLOC4,CDK5,FARSA,NUP210,MLX,NEK6,NDUFA2,RCSD1,ZNRD1,AMPD2,HARS,ZMYND11,SSR2,RHBDF2,C1orf122,CDCA4,SERF2,GPS2,STK38,SETD3,MAFK,STX18,SIL1,CCDC125,EHD4 |
| 3.026e-02 | -3.50 | GSE3565_DUSP1_VS_WT_SPLENOCYTES_DN | MSigDB lists | GSE3565_DUSP1_VS_WT_SPLENOCYTES_DN | 169 | 35 | 17377 | 2626 |
TCF12,DNMT3A,ADD1,RPS6KA1,TOP2B,PCBP1,RAPGEF6,PIP4K2A,TFRC,ADD3,CTNNBL1,HDAC7,IL6ST,ARHGEF1,FBL,N4BP2,SMC4,TIMP2,KAT2A,ETV3,MAP4K4,RPL8,RPS10,RAB3IP,UBE4B,TANC1,RBM38,RPL36,GNAS,USF2,RPS26,ACSF2,EYA2,GPATCH4,TMEM131 |
| 3.026e-02 | -3.50 | GSE9960_HEALTHY_VS_GRAM_NEG_AND_POS_SEPSIS_PBMC_DN | MSigDB lists | GSE9960_HEALTHY_VS_GRAM_NEG_AND_POS_SEPSIS_PBMC_DN | 169 | 35 | 17377 | 2626 |
SLC30A9,CMAS,GOLIM4,LYRM4,PTTG1,CYCS,NHLRC3,UBQLN2,CCNB1,SLC25A43,TTF1,SCYL2,ASPHD2,ZNF302,KDM2A,TIMM23,ZNF189,VPS13B,TXNL1,PPP3CA,ADAM17,ELL2,LRBA,LYRM1,RFFL,NUP155,DIDO1,API5,KRIT1,FBXO21,KLHL15,SAMD8,SLAIN1,ZBTB11,STARD3NL |
| 3.029e-02 | -3.50 | FARMER_BREAST_CANCER_APOCRINE_VS_LUMINAL | MSigDB lists | FARMER_BREAST_CANCER_APOCRINE_VS_LUMINAL | 308 | 59 | 17377 | 2626 |
SEPHS2,ANKRD27,FAM208B,PNISR,SUZ12,DAP,PRKAA1,TMX4,MCCC1,C5orf30,MED13L,AGFG1,REEP5,MYL6B,SSR1,APLP2,SLC31A1,MDM2,MZT2A,RABGAP1L,IL6ST,CDKN1B,YBX1,BCL2,ACAD8,SMARCE1,ABCC5,FDFT1,ANKLE2,PPIF,ABHD2,TK1,NRAS,TSTA3,HMGN4,BTG2,ACSL3,SREK1,HEBP2,C14orf132,ASB13,POLG2,CYB5A,OPTN,VEZF1,PON2,PDLIM1,CCDC6,U2SURP,CTBS,DBI,PGRMC1,ADAM9,ANP32E,FKBP5,ACADM,CLU,MAP3K5,TRAF5 |
| 3.031e-02 | -3.50 | angioimmunoblastic_T_cell_lymphoma | COSMIC cancer mutations | angioimmunoblastic_T_cell_lymphoma | 271 | 52 | 17385 | 2587 |
DNMT3A,ARID2,NF1,SF3B1,MUM1,MRPL39,SHPRH,SUZ12,SMARCA4,CTCF,NOTCH2,ETS1,ARID1B,CHD1,DST,IRF4,RB1,CTSS,BRPF3,HUWE1,PTEN,HDAC7,ETV6,PTPN11,PDS5B,BRD7,TTC3,BCL2,STAT3,HP1BP3,NRAS,RHOA,BRD4,CELSR2,TNFAIP3,TACC1,BTG2,MKI67,KRAS,ARID1A,KMT2C,PHF6,FAS,ZMYM3,GNAS,JAK1,STAT6,ACTB,CHEK2,MAPK1,CDKN2A,PARD3 |
| 3.032e-02 | -3.50 | skin-ear-carcinoma-squamous_cell_carcinoma | COSMIC cancer mutations | skin-ear-carcinoma-squamous_cell_carcinoma | 513 | 92 | 17385 | 2587 |
WASF2,AGRN,GNPNAT1,NF1,GNPDA1,FAM129A,PPP1R15B,NIT2,CLCC1,PLXNA1,SAFB2,POLR3K,CHD1,FANCI,EEF2K,ZNF804A,AHCTF1,PIN1,RAD23B,TIPARP,USP34,ORAI2,ERCC1,SGCE,ZCCHC10,NRAS,VHL,NUP155,TOR1AIP2,LRP5,KMT2C,KDM1B,EIF3A,RAD54B,AHNAK,PEX5,CHD3,RBL1,TICAM1,NCLN,ZBTB11,POT1,DYNC1LI2,ZNF146,NUMB,HIVEP3,NADSYN1,PKP4,CENPF,CCM2,ACAP1,CDCA8,DHX9,NOTCH2,B4GALT4,PDXDC1,DDRGK1,C12orf10,FGFR3,NDUFV1,PTEN,CRAT,PHKG2,MSH6,HP1BP3,ZFP64,AGGF1,DHX29,PSPC1,MRS2,UTP15,ITM2A,GORASP2,KRAS,THNSL1,PLEC,UBE4B,OTUD3,NCDN,MASTL,MTMR3,PTPRF,GALNT2,ZC3H7B,MED15,EXOC4,IMPDH1,CABIN1,MAP3K5,HRAS,GCSH,CDKN2A |
| 3.037e-02 | -3.49 | GO_DOUBLE_STRANDED_DNA_BINDING | MSigDB lists | GO_DOUBLE_STRANDED_DNA_BINDING | 731 | 129 | 17377 | 2626 |
MAX,H2AFZ,CXXC1,KIF2C,PARK7,CREM,MBD4,USF1,PCNA,ZNF639,ETV6,XRCC2,CRY2,NUP153,MYBL1,SMARCE1,DNMT1,SP3,TDP1,KLF10,BAZ2A,GABPA,RAD51AP1,EAF2,SOX4,MCM2,UBTF,HHEX,SMAD2,E2F4,ACTB,SMAD1,HDAC2,DDX58,CTCF,MEF2A,THRAP3,ZNF79,TFAP4,NFATC3,MLX,KLF16,MCM5,MBD2,ZNF746,ZNF335,MSH2,YBX1,TNRC18,TERF2,ETV3,FOXK1,ZMYND11,MTA2,LDB1,MYBL2,ELK1,KDM3A,XRCC5,RXRB,ETS2,NFIL3,CEBPG,NLRC5,RUVBL2,YY1,RBBP4,TCF12,MBD1,SUZ12,PMS2,SMARCA4,IRF3,MXD1,RRN3,NRF1,MTA1,GMEB1,AKAP8,TARDBP,ATF2,CGGBP1,ZNF583,PCGF6,WBP2,NFATC2,MEF2D,MBD3,RAD51C,MAFK,SAFB,STAT6,ARNTL,STAT1,RBMS1,ATF6,XRCC3,BEND3,AKNA,H3F3A,ZBTB11,SMAD4,RAD51D,POU3F2,MCM10,MECP2,TCF3,KLF13,ZNF92,IRF4,SUV39H2,H2AFY,ORC3,CREB1,STAT3,MSH6,NCOA2,PRKDC,PSPC1,MEN1,KLF6,NEIL3,TFE3,PITX1,HMGB2,RBPJ,TERF1,PURA,IFI16 |
| 3.039e-02 | -3.49 | vesicle lumen | cellular component | GO:0031983 | 338 | 63 | 18223 | 2701 |
ADA2,MIF,HSPH1,GMFG,HEXB,SRGN,OLA1,NIT2,MAN2B1,NHLRC3,GYG1,MAPK14,APP,FERMT3,PCYOX1L,GNS,PSMD2,PA2G4,PSMD1,ARPC5,HUWE1,OSTF1,CNN2,APOOL,MVP,GM2A,SPTAN1,TGFB1,FTL,CCT2,CYFIP1,TIMP2,FAM49B,CREG1,ARHGAP45,PPIE,PSMB7,HEBP2,C1orf35,PKM,TOLLIP,ARMC8,CCT8,NEU1,CAND1,XRCC5,CAT,MAGED2,DSN1,PSMD3,FAM3C,ACLY,CANT1,IMPDH1,CAB39,CTSA,ROCK1,PDXK,GPI,CLU,PGAM1,MAPK1,TUBB |
| 3.042e-02 | -3.49 | human chr21q21.3 | chromosome location | human chr21q21.3 | 29 | 7 | 26185 | 2809 |
LTN1,ATP5PF,GABPA,MAP3K7CL,MRPL39,APP,CCT8 |
| 3.042e-02 | -3.49 | GO_REGULATION_OF_PEPTIDYL_THREONINE_PHOSPHORYLATION | MSigDB lists | GO_REGULATION_OF_PEPTIDYL_THREONINE_PHOSPHORYLATION | 35 | 10 | 17377 | 2626 |
TGFB1,PLK1,CALM2,AXIN1,OGT,CAB39,SIRT2,S1PR2,MAPK1,PARD3 |
| 3.042e-02 | -3.49 | GO_TRANSCRIPTION_ELONGATION_FACTOR_COMPLEX | MSigDB lists | GO_TRANSCRIPTION_ELONGATION_FACTOR_COMPLEX | 35 | 10 | 17377 | 2626 |
PAF1,RB1,TONSL,ELL2,ELP4,CTR9,RTF1,AFF1,EAF2,CDC73 |
| 3.042e-02 | -3.49 | chr12q14 | MSigDB lists | chr12q14 | 35 | 10 | 17377 | 2626 |
GNS,CCT2,MDM2,TMBIM4,OSBPL8,HELB,NUP107,LLPH,RAB3IP,CAND1 |
| 3.042e-02 | -3.49 | GO_HISTONE_LYSINE_N_METHYLTRANSFERASE_ACTIVITY | MSigDB lists | GO_HISTONE_LYSINE_N_METHYLTRANSFERASE_ACTIVITY | 35 | 10 | 17377 | 2626 |
ASH1L,SUV39H2,CXXC1,SETD3,EHMT1,WDR82,EZH1,MEN1,WDR5,DOT1L |
| 3.042e-02 | -3.49 | GO_POSITIVE_REGULATION_OF_MITOCHONDRIAL_OUTER_MEMBRANE_PERMEABILIZATION_INVOLVED_IN_APOPTOTIC_SIGNALING_PATHWAY | MSigDB lists | GO_POSITIVE_REGULATION_OF_MITOCHONDRIAL_OUTER_MEMBRANE_PERMEABILIZATION_INVOLVED_IN_APOPTOTIC_SIGNALING_PATHWAY | 35 | 10 | 17377 | 2626 |
BAK1,SIVA1,DYNLL1,TFDP1,E2F1,PPP3R1,YWHAZ,BCL2,TP53BP2,YWHAH |
| 3.042e-02 | -3.49 | GCM_CSNK1A1 | MSigDB lists | GCM_CSNK1A1 | 35 | 10 | 17377 | 2626 |
LARS,SNRNP200,RBM25,PPP1R15B,TOR1AIP1,ATP2C1,CHTOP,CSNK1A1,LUC7L2,DHX15 |
| 3.042e-02 | -3.49 | CHANDRAN_METASTASIS_TOP50_UP | MSigDB lists | CHANDRAN_METASTASIS_TOP50_UP | 35 | 10 | 17377 | 2626 |
NOL8,U2SURP,YY1,SEPT7,H2AFV,PABPC1,CBX4,KIAA1147,PCBP2,DDX17 |
| 3.042e-02 | -3.49 | QI_HYPOXIA_TARGETS_OF_HIF1A_AND_FOXA2 | MSigDB lists | QI_HYPOXIA_TARGETS_OF_HIF1A_AND_FOXA2 | 35 | 10 | 17377 | 2626 |
SRM,BCL2L1,IP6K2,CITED2,KDM3A,MARK2,PPM1G,CARM1,CNOT3,ABCF2 |
| 3.042e-02 | -3.49 | GO_NEGATIVE_REGULATION_OF_INNATE_IMMUNE_RESPONSE | MSigDB lists | GO_NEGATIVE_REGULATION_OF_INNATE_IMMUNE_RESPONSE | 35 | 10 | 17377 | 2626 |
PTPN2,HLA-B,TRAFD1,TNFAIP3,ARRB2,HLA-E,HLA-A,IFI16,TAP1,NLRC5 |
| 3.046e-02 | -3.49 | JADE1 (jade family PHD finger 1) | protein interactions | 79960 | 24 | 8 | 17029 | 2761 |
PLK1,NPHP4,TK1,VHL,KAT7,YJU2,SEPT8,MEAF6 |
| 3.046e-02 | -3.49 | PSMC3IP (PSMC3 interacting protein) | protein interactions | 29893 | 24 | 8 | 17029 | 2761 |
PTPN2,TGFB1,BRMS1,MND1,RB1CC1,XRCC3,NOTCH2,CHEK2 |
| 3.046e-02 | -3.49 | LTA4H (leukotriene A4 hydrolase) | protein interactions | 4048 | 24 | 8 | 17029 | 2761 |
KRAS,PRPF4,TAGLN2,GALK2,FKBP2,SPR,DDA1,UBA5 |
| 3.046e-02 | -3.49 | ZBTB46 (zinc finger and BTB domain containing 46) | protein interactions | 140685 | 24 | 8 | 17029 | 2761 |
CUL1,FBXO21,ZBTB10,SNRNP200,MBD3,MTA1,EHMT1,DDX23 |
| 3.046e-02 | -3.49 | ATAD5 (ATPase family, AAA domain containing 5) | protein interactions | 79915 | 24 | 8 | 17029 | 2761 |
PCNA,FNTA,BRD4,CSNK2A1,BAZ1B,CHEK2,WDR48,MIS12 |
| 3.046e-02 | -3.49 | RAB3GAP2 (RAB3 GTPase activating non-catalytic protein subunit 2) | protein interactions | 25782 | 24 | 8 | 17029 | 2761 |
UTP20,EXOSC6,SHC1,GABPA,GNE,PTP4A3,SIRT2,LMAN1 |
| 3.046e-02 | -3.49 | ESF1 (ESF1 nucleolar pre-rRNA processing protein homolog) | protein interactions | 51575 | 24 | 8 | 17029 | 2761 |
AATF,MECP2,FBXO7,UTP3,SEPT7,GAR1,IFI16,DDX52 |
| 3.046e-02 | -3.49 | TADA1 (transcriptional adaptor 1) | protein interactions | 117143 | 24 | 8 | 17029 | 2761 |
TAF5L,SUPT20H,TAF6L,USP22,TAF12,KAT2A,SUPT7L,SGF29 |
| 3.046e-02 | -3.49 | MTMR12 (myotubularin related protein 12) | protein interactions | 54545 | 24 | 8 | 17029 | 2761 |
RTCB,TIMM21,MTMR12,NDUFS8,CYC1,NPLOC4,HAUS8,MAPK3 |
| 3.046e-02 | -3.49 | NAA40 (N(alpha)-acetyltransferase 40, NatD catalytic subunit) | protein interactions | 79829 | 24 | 8 | 17029 | 2761 |
WDR11,DHX16,TPP2,H2AFY,MCM2,GLRX3,SUPT16H,SSRP1 |
| 3.046e-02 | -3.49 | ATP6V1C2 (ATPase H+ transporting V1 subunit C2) | protein interactions | 245973 | 24 | 8 | 17029 | 2761 |
PDCD10,ATP6V1D,GOLGA2,TTC9C,ATP6V1B2,ATP6V1C1,ZC3HC1,ATP6V1G1 |
| 3.046e-02 | -3.49 | tax (p40) | protein interactions | 1491938 | 24 | 8 | 17029 | 2761 |
RHOA,ANXA6,CDC42,MBD2,RAC1,SMARCA4,SMARCE1,CDK2 |
| 3.046e-02 | -3.49 | Prkaa1 (protein kinase, AMP-activated, alpha 1 catalytic subunit) | protein interactions | 105787 | 24 | 8 | 17029 | 2761 |
GNS,PRKAB1,PMS2,GEMIN6,BCLAF1,RANGAP1,NFU1,TAGLN2 |
| 3.046e-02 | -3.49 | LRRFIP2 (LRR binding FLII interacting protein 2) | protein interactions | 9209 | 24 | 8 | 17029 | 2761 |
KARS,MYO18A,CAPZA1,MYH9,CAPZA2,STAT3,CDK2,IFI16 |
| 3.046e-02 | -3.49 | BSPRY (B-box and SPRY domain containing) | protein interactions | 54836 | 24 | 8 | 17029 | 2761 |
DEAF1,RAB11B,MBLAC2,CEP55,FEM1B,HAUS4,YWHAZ,RNF135 |
| 3.046e-02 | -3.49 | Nhsl1 (NHS-like 1) | protein interactions | 215819 | 24 | 8 | 17029 | 2761 |
PPP2CA,CYFIP1,KPNA4,MCM5,NCKAP1,H3F3A,SEC16A,ABI1 |
| 3.046e-02 | -3.49 | MBD3L1 (methyl-CpG binding domain protein 3 like 1) | protein interactions | 85509 | 24 | 8 | 17029 | 2761 |
ZNF296,RBBP4,CHD3,MBD3,MTA1,MTA2,MBD2,HDAC2 |
| 3.046e-02 | -3.49 | NOP10 (NOP10 ribonucleoprotein) | protein interactions | 55505 | 24 | 8 | 17029 | 2761 |
SYNCRIP,RBM34,KRAS,SNRNP70,GAR1,ARRB2,ZC3H3,WDR48 |
| 3.046e-02 | -3.49 | MTHFD2 (methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase) | protein interactions | 10797 | 24 | 8 | 17029 | 2761 |
PTEN,HUWE1,DHX29,CUL3,NFATC2,HRAS,GCC1,LMNA |
| 3.046e-02 | -3.49 | ELL2 (elongation factor for RNA polymerase II 2) | protein interactions | 22936 | 24 | 8 | 17029 | 2761 |
SIAH1,CTR9,TIA1,SLC4A2,AFF1,EAF2,PIP4K2A,ESYT2 |
| 3.046e-02 | -3.49 | MAGEC2 (MAGE family member C2) | protein interactions | 51438 | 24 | 8 | 17029 | 2761 |
CUL1,NSMCE4A,TRIM8,RBX1,STAT3,ZMYND11,TRIM28,PCGF6 |
| 3.046e-02 | -3.49 | CCDC115 (coiled-coil domain containing 115) | protein interactions | 84317 | 24 | 8 | 17029 | 2761 |
PLK1,ATP6V0A2,TK1,ATP6V0D1,APP,ATP6V0E1,RAB7A,TMEM216 |
| 3.046e-02 | -3.49 | FBXL17 (F-box and leucine rich repeat protein 17) | protein interactions | 64839 | 24 | 8 | 17029 | 2761 |
ZBTB10,KLHL20,PPM1G,KBTBD7,CUL3,CUL1,NOTCH2,DVL2 |
| 3.046e-02 | -3.49 | C10orf88 (chromosome 10 open reading frame 88) | protein interactions | 80007 | 24 | 8 | 17029 | 2761 |
IMMT,DCAF6,KLHL15,LNX2,NCKAP1,DOCK11,APP,ABI1 |
| 3.050e-02 | -3.49 | DNA helicase activity | molecular function | GO:0003678 | 49 | 13 | 17224 | 2647 |
GINS1,RECQL,CHD3,HELB,TWNK,CHD1L,DHX9,RUVBL2,BLM,CHD1,GINS4,RAD54B,XRCC5 |
| 3.054e-02 | -3.49 | Hh mutants abrogate ligand secretion | REACTOME pathways | R-HSA-5387390 | 60 | 16 | 10287 | 1696 |
PSMA8,PSMB7,PSMA1,SYVN1,PSMB9,PSMD9,PSMB3,PSMC4,PSMD2,PSMA6,PSMD1,RPS27A,PSMD3,PSMD8,SEL1L,PSMC1 |
| 3.055e-02 | -3.49 | regulation of mitotic spindle assembly | biological process | GO:1901673 | 21 | 7 | 17256 | 2622 |
PLK1,CHMP4B,CHMP2A,SMC3,PDCD6IP,CHMP2B,HSPA1B |
| 3.055e-02 | -3.49 | viral budding via host ESCRT complex | biological process | GO:0039702 | 21 | 7 | 17256 | 2622 |
CHMP4B,CHMP2A,CHMP4A,PDCD6IP,VPS4A,CHMP2B,CHMP7 |
| 3.055e-02 | -3.49 | positive regulation of gene silencing by miRNA | biological process | GO:2000637 | 21 | 7 | 17256 | 2622 |
TGFB1,DDX5,FXR1,STAT3,MAP2K2,AGO2,DHX9 |
| 3.055e-02 | -3.49 | protein-DNA complex disassembly | biological process | GO:0032986 | 21 | 7 | 17256 | 2622 |
SMARCA4,ARID1A,PBRM1,SMARCE1,ARID2,SUPT16H,SMARCD1 |
| 3.058e-02 | -3.49 | regulation of extrinsic apoptotic signaling pathway | biological process | GO:2001236 | 157 | 33 | 17256 | 2622 |
GCLM,CYLD,NF1,RAF1,EYA1,BCL2L1,PARK7,LMNA,CFLAR,SP100,PTEN,DAPK1,FEM1B,ARHGEF2,BCL2,TMBIM1,HTRA2,TNFAIP3,RB1CC1,ZMYND11,RFFL,MCL1,BRCA1,FADD,DAPK3,HSPA1B,FAS,PML,SIAH2,HMGB2,EYA2,FAF1,ZC3HC1 |
| 3.062e-02 | -3.49 | ACTWSNACTNY_UNKNOWN | MSigDB lists | ACTWSNACTNY_UNKNOWN | 97 | 22 | 17377 | 2626 |
STAU1,TMEM115,TRAF7,KAT2A,ZCCHC8,APH1A,POLK,ADO,WDTC1,TOP3A,INO80E,COPG2,MYL6B,TMEM69,MRPL50,CCNA2,BBX,DNAJC17,GNAI2,ESPL1,NUMB,ZNF189 |
| 3.063e-02 | -3.49 | lung-carcinoma-acinar_adenocarcinoma | COSMIC cancer mutations | lung-carcinoma-acinar_adenocarcinoma | 26 | 8 | 17385 | 2587 |
KIF5B,KRAS,FGFR3,STK11,NRAS,PTEN,EML4,SMAD4 |
| 3.067e-02 | -3.48 | GAZDA_DIAMOND_BLACKFAN_ANEMIA_PROGENITOR_DN | MSigDB lists | GAZDA_DIAMOND_BLACKFAN_ANEMIA_PROGENITOR_DN | 60 | 15 | 17377 | 2626 |
RB1,NAP1L1,SEC61A1,MAGT1,ZNF84,CASP6,PFDN4,PRKDC,RAB4A,NUP54,SMARCA4,PXMP2,CHPF2,GCSH,RPL36 |
| 3.067e-02 | -3.48 | GCM_ING1 | MSigDB lists | GCM_ING1 | 60 | 15 | 17377 | 2626 |
DDX47,TRAFD1,MTMR4,THAP4,SAFB,PRDM4,CS,TMX3,KLHL18,RABIF,SUMF2,MBD3,GFM2,ABHD16A,S100PBP |
| 3.067e-02 | -3.48 | GO_NEGATIVE_REGULATION_OF_CELLULAR_PROTEIN_CATABOLIC_PROCESS | MSigDB lists | GO_NEGATIVE_REGULATION_OF_CELLULAR_PROTEIN_CATABOLIC_PROCESS | 60 | 15 | 17377 | 2626 |
PLK1,ZNF207,PBK,UBXN1,CENPF,PML,CSNK2A1,PSEN1,PARK7,TERF1,SENP1,MAD2L2,PDCL3,CDKN2A,SVIP |
| 3.069e-02 | -3.48 | thymic_carcinoma | COSMIC cancer mutations | thymic_carcinoma | 17 | 6 | 17385 | 2587 |
KRAS,NRAS,MEN1,PTEN,HRAS,CDKN2A |
| 3.069e-02 | -3.48 | myoepithelial_carcinoma | COSMIC cancer mutations | myoepithelial_carcinoma | 17 | 6 | 17385 | 2587 |
KRAS,STK11,NRAS,PTEN,HRAS,SMAD4 |
| 3.069e-02 | -3.48 | salivary_gland-carcinoma-myoepithelial_carcinoma | COSMIC cancer mutations | salivary_gland-carcinoma-myoepithelial_carcinoma | 17 | 6 | 17385 | 2587 |
KRAS,STK11,NRAS,PTEN,HRAS,SMAD4 |
| 3.069e-02 | -3.48 | salivary_gland-carcinoma-salivary_duct_carcinoma | COSMIC cancer mutations | salivary_gland-carcinoma-salivary_duct_carcinoma | 17 | 6 | 17385 | 2587 |
KRAS,STK11,NRAS,PTEN,HRAS,SMAD4 |
| 3.069e-02 | -3.48 | hypothalamus | COSMIC cancer mutations | hypothalamus | 17 | 6 | 17385 | 2587 |
KRAS,NRAS,H3F3A,HRAS,CDKN2A,CLCN6 |
| 3.069e-02 | -3.48 | central_nervous_system-temporal_lobe-glioma-astrocytoma_Grade_II | COSMIC cancer mutations | central_nervous_system-temporal_lobe-glioma-astrocytoma_Grade_II | 17 | 6 | 17385 | 2587 |
KRAS,H3F3A,CHERP,PTEN,VHL,CDKN2A |
| 3.082e-02 | -3.48 | GSE33425_CD161_HIGH_VS_NEG_CD8_TCELL_UP | MSigDB lists | GSE33425_CD161_HIGH_VS_NEG_CD8_TCELL_UP | 192 | 39 | 17377 | 2626 |
RHOG,IER2,TRIP12,CXXC1,CDT1,TMEM109,PTP4A3,VAV1,RAB21,VASP,MLX,RALB,CTR9,BCL2,DNMT1,CGGBP1,LDHB,RRM2,ITM2A,WDHD1,FRAT2,RAB3IP,ADRB2,SMC2,FOXRED1,EIF4G2,MARK2,IRF5,BSDC1,PI4K2A,PLD3,HHEX,TRIM47,CSK,ARNTL,CTSA,AP2S1,DDB1,FUBP1 |
| 3.082e-02 | -3.48 | GSE5679_CTRL_VS_PPARG_LIGAND_ROSIGLITAZONE_AND_RARA_AGONIST_AM580_TREATED_DC_UP | MSigDB lists | GSE5679_CTRL_VS_PPARG_LIGAND_ROSIGLITAZONE_AND_RARA_AGONIST_AM580_TREATED_DC_UP | 192 | 39 | 17377 | 2626 |
SEPHS2,PKP4,RWDD1,AGTRAP,HLA-E,TAP1,KLF13,COPB2,CFLAR,HOMER1,CLIC4,IMPAD1,AFF1,POLR1B,STAT3,PHKG2,ARL5A,PPA1,ABCC5,USO1,BRD4,MLEC,ATP2C1,LDHA,RRM2,BMS1,UHRF1BP1,LY6E,PRDX1,ISG15,NMT2,UTP20,SLC19A1,DCK,TBPL1,LY75,NUP62,DVL1,GALNT10 |
| 3.082e-02 | -3.48 | GSE17721_PAM3CSK4_VS_GADIQUIMOD_0.5H_BMDC_DN | MSigDB lists | GSE17721_PAM3CSK4_VS_GADIQUIMOD_0.5H_BMDC_DN | 192 | 39 | 17377 | 2626 |
RRP15,TSC22D3,WDR13,VAV2,ANKH,C19orf25,EPHX2,DUSP22,RUFY1,TTF1,MED8,PPIL2,NAP1L4,PLCL2,TNRC18,SRPK2,CDC5L,TRIM8,TK1,PIGT,PRIM2,ERLIN1,UBE2V1,MTX1,NFATC2IP,CYFIP2,FXR1,RAB22A,MAK16,POLR2A,TBC1D17,GOLGA2,DHX16,CCDC6,COX7A2L,PPP3R1,MAPK1,NRBP1,PTOV1 |
| 3.082e-02 | -3.48 | GSE19923_E2A_KO_VS_E2A_AND_HEB_KO_DP_THYMOCYTE_DN | MSigDB lists | GSE19923_E2A_KO_VS_E2A_AND_HEB_KO_DP_THYMOCYTE_DN | 192 | 39 | 17377 | 2626 |
SLC12A7,NOP2,CASP6,DAP,SRGN,EIF3D,PMS2,NCKAP1,RUFY1,HDDC2,DNAJB9,CAPN2,CDK5,NUS1,PSMA6,TANK,SLC44A1,ANXA5,NFU1,RPL22L1,KCNAB2,PRPF19,SRSF11,SEPT9,ELL2,LAP3,NSUN2,LRBA,UTP3,ISG15,ECH1,ZNF282,GADD45B,MAPK6,PPA2,MRFAP1L1,PLOD3,RRS1,TSPAN5 |
| 3.082e-02 | -3.48 | GSE27434_WT_VS_DNMT1_KO_TREG_DN | MSigDB lists | GSE27434_WT_VS_DNMT1_KO_TREG_DN | 192 | 39 | 17377 | 2626 |
UBE2D3,IER2,GMFG,SRGN,CSNK1A1,SLC20A1,PRNP,ANKRD28,CRKL,MDM2,TNFAIP8,PTEN,TANK,ATP13A3,EI24,TRA2B,EIF5,SRSF11,YTHDC1,IFRD1,PPP3CA,BIRC3,CSRP1,BTG2,GTPBP4,ILF3,KRAS,DNAJA1,RHOB,RAB18,ETS2,HNRNPR,GADD45B,DDX5,B4GALT3,TMEM159,CPEB2,NMD3,RAB3IL1 |
| 3.082e-02 | -3.48 | CHANG_CORE_SERUM_RESPONSE_DN | MSigDB lists | CHANG_CORE_SERUM_RESPONSE_DN | 192 | 39 | 17377 | 2626 |
HECA,HABP4,SUMF1,NHLRC3,CCNL2,DUSP22,APP,MAN1A1,SLC25A36,PDK2,ADD3,KLHL5,TNFAIP8,SNX18,DPYSL2,IL6ST,MEGF8,CLCN6,AXIN2,SEPT11,PIK3IP1,SAP30L,TIMP2,PBXIP1,ACSL3,LDB1,WBP2,ATP6V0A1,MEF2D,H2AFV,RPL37,PLD3,SERF2,OSBPL8,SNRNP70,TFDP2,IGBP1,ZMAT3,ANXA11 |
| 3.082e-02 | -3.48 | GSE34006_A2AR_KO_VS_A2AR_AGONIST_TREATED_TREG_UP | MSigDB lists | GSE34006_A2AR_KO_VS_A2AR_AGONIST_TREATED_TREG_UP | 192 | 39 | 17377 | 2626 |
FAM208B,FEZ2,PARP12,TMEM184B,AGRN,HLA-E,UBR2,TOR3A,TOR1AIP1,TAP1,SECISBP2,CRLF3,RAPGEF6,CMTM6,RNF135,PPA1,NSUN4,MORC3,TRAFD1,DDX24,RAD51AP1,TOR1AIP2,RAB3IP,ASB13,OGFR,PSMB9,ISG15,HLA-B,TRIM26,KEAP1,RBL1,ZNF689,STAT1,DCAF11,PML,CHMP4B,NAA20,RNF14,RNF114 |
| 3.082e-02 | -3.48 | GSE43955_1H_VS_60H_ACT_CD4_TCELL_UP | MSigDB lists | GSE43955_1H_VS_60H_ACT_CD4_TCELL_UP | 192 | 39 | 17377 | 2626 |
MAPRE1,EIF3D,TRIO,STRN4,MRPS26,PCSK7,AGFG1,SNRPD3,COMMD5,CSNK1A1,SEC11A,RPA2,CLIC4,NDUFA2,AP3S2,FEM1B,MDFIC,SLC38A10,ALDH9A1,FYTTD1,CYTH1,CYFIP1,ADAM17,SELPLG,TOR1AIP2,MAP7D1,NUTF2,GUF1,ARPC1A,ZFAND5,SNRPA,ZFR,CHCHD3,EPRS,RAB24,PRDX5,CPEB2,HIPK3,SMNDC1 |
| 3.084e-02 | -3.48 | GO_RESPONSE_TO_ABIOTIC_STIMULUS | MSigDB lists | GO_RESPONSE_TO_ABIOTIC_STIMULUS | 985 | 170 | 17377 | 2626 |
NPHP4,TXN,NF1,TSC22D3,TMEM109,ALKBH5,SLC29A1,SIRT2,IKBIP,CCNB1,MAPK14,BECN1,ANKRD23,RBM4,BIRC2,MBD4,EEF2K,CDK5,USF1,PCNA,RCSD1,XRCC2,DNM2,NOC2L,AKR1B1,CRY2,DNMT1,MTPN,OGG1,PTPRK,PLK3,BAK1,DEAF1,ERCC1,RBX1,AKT2,VHL,RAD51AP1,PBK,MKI67,AURKB,BRCA1,MAP3K4,RAD18,RPS27A,ITGB1,CAB39,STK11,CHEK2,CLU,FBXL3,ARRB2,HDAC2,UBE2D3,AGTRAP,PRKAA1,SDC2,RRM1,EIF2AK4,RHBDD1,LMNA,DTL,INTS7,HDAC7,XPA,MSH2,TIMELESS,BCL2,AHCY,EEF1D,HP1BP3,GBA,KRAS,MAP4K3,UBE4B,ADRB2,ELK1,KDM3A,RHOB,XRCC5,RDH11,FAS,ADSS,CAT,TSC1,PDLIM1,RUVBL2,YY1,CDK2,EGLN1,ATXN3,DNMT3A,RAB11B,RAF1,SLC2A1,RAC1,BCL2L1,SNN,LYN,APP,RPAIN,NRF1,MDM2,CCNA2,SHC1,STRBP,MTA1,CLCN6,CDKN1B,ATF2,HTRA2,BTG2,POLR2D,CIRBP,LRRC8A,DNAJA1,DCLRE1C,TANC1,PSMB9,RAD54B,RAD51C,ATP1A1,SCAP,HIPK2,H2AFX,XRCC3,TRIM32,XRCC4,SMAD4,RAD51D,MECP2,EYA1,HABP4,BABAM1,PAWR,BLM,ETS1,TFRC,CAPN2,RFWD3,CTSS,SUV39H2,PTEN,ARHGEF2,CNN2,MAP3K14,CREB1,CITED2,GTF2H2,MSH6,PDPK1,TGFB1,ADAM17,NET1,PRKDC,LDHA,MEN1,FADD,HSPA1B,MAPK3,PDCD6,PML,E2F1,AEN,IMPDH1,PKD2,RBPJ,CPEB2,DDB1,IFI16 |
| 3.088e-02 | -3.48 | ANP32A (acidic nuclear phosphoprotein 32 family member A) | protein interactions | 8125 | 61 | 16 | 17029 | 2761 |
ATXN1,PKM,PCBP1,CHAF1A,RPA2,DERL1,TPD52L2,KPNA1,EIF4A3,AXIN1,NSFL1C,ANP32E,B4GALT3,AHCYL1,PDLIM5,SSRP1 |
| 3.088e-02 | -3.48 | RNF7 (ring finger protein 7) | protein interactions | 9616 | 61 | 16 | 17029 | 2761 |
UBE2D3,TRIM8,VHL,CUL3,CUL1,UBE2Q1,CSNK2A1,CYCS,ERBIN,DCUN1D5,ASB13,DCUN1D4,CBFB,UBE2C,ASB6,UBE2M |
| 3.088e-02 | -3.48 | ROCK1 (Rho associated coiled-coil containing protein kinase 1) | protein interactions | 6093 | 61 | 16 | 17029 | 2761 |
CYLD,RHOA,ADD1,PPP1R12A,RHOC,EZR,XRCC5,SMAD2,HGS,PTEN,NEIL3,LIMK1,DPYSL2,ROCK1,SMURF1,CFL1 |
| 3.088e-02 | -3.48 | FGFR3 (fibroblast growth factor receptor 3) | protein interactions | 2261 | 61 | 16 | 17029 | 2761 |
POLA2,BRD4,VHL,SDC2,RPL8,BORA,HSPA1B,FGFR3,HSPA4,FNTA,ARAP1,STAT1,STAT3,ILKAP,CDC37,SRPK2 |
| 3.091e-02 | -3.48 | EMC2 (ER membrane protein complex subunit 2) | protein interactions | 9694 | 106 | 25 | 17029 | 2761 |
DDX28,HNRNPAB,CHERP,PHB2,TRIR,SF3B1,TMEM216,HDGFL2,AP3S1,SAFB2,SDHA,ABCF1,KTN1,SF3A2,EVC2,SF3B2,RBM17,HNRNPA2B1,DNAJC8,NSRP1,IMPDH1,FUS,LRRC59,ZMAT3,CCAR1 |
| 3.091e-02 | -3.48 | Nedd1 (neural precursor cell expressed, developmentally down-regulated gene 1) | protein interactions | 17997 | 106 | 25 | 17029 | 2761 |
EIF5A,CCT2,MLEC,TXN,FOPNL,ZFP91,PRKAA1,TUBGCP5,SMU1,NARF,EFL1,GAR1,TUBGCP2,CCT8,CAND1,DAP3,MZT2A,PCM1,PDCD6,SYNCRIP,CCP110,MED10,NAP1L4,S100A6,VPS13B |
| 3.091e-02 | -3.48 | prostate | COSMIC cancer mutations | prostate | 14295 | 2161 | 17385 | 2587 |
HECA,ZBTB10,ABCC10,HEXB,TGOLN2,CCNL2,FBXO22,EEF2K,THAP4,RAD23B,ATP13A3,DNM2,FTSJ3,USP34,CCDC57,ERCC1,NRAS,EHMT1,KIF15,HNRNPF,WDHD1,MIER2,DIDO1,RAB22A,SMAD2,MID1IP1,RPS27A,MYO18A,OGT,MPV17,COX5A,SMAD1,ZNF75A,ANXA11,SLC25A33,ZNF720,GGA1,MUM1,CCZ1,TRIO,CUTA,RAB23,KCTD17,EIF2AK4,APH1B,PARN,CDC73,MYL6B,ATG4A,ERV3-1,SMC3,C4orf3,GEMIN4,NUP85,PABPC1,NSUN4,PPA1,IFRD1,AGGF1,FOXK1,RBM42,GTPBP4,MAP7D1,MRPL16,ELK1,EIF4H,RDH11,MAGED2,KPNA1,ETS2,TYW5,WIPI2,RUFY3,PDLIM5,ACSF2,FAM72D,EXOC3,C5orf30,VTI1A,RCOR3,LCLAT1,CPNE3,KIAA1147,RBM23,ZNF420,AHCTF1,TBC1D22A,TBC1D14,NSFL1C,SEPT11,GPD1L,ZC3H3,ARL5A,PDCL3,SNX8,ERMP1,EID1,IDH3A,POLR2D,MEF2D,TMEM147,TANC1,MAT2A,NSMCE2,CORO1C,CAMKMT,PPP5C,PITRM1,TUBB,COMMD10,ZNF445,HABP4,CCM2,FLOT1,BTN3A1,ATG2B,PPP1R3B,GOLM1,HUWE1,NAA50,ANXA5,LTN1,UBE3B,NAP1L4,ZNF710,ST8SIA2,RPL22L1,SPTAN1,STAU1,DDX24,TCTEX1D2,TACC1,MRS2,LDHA,HEBP2,RAB3IP,TTC33,PICALM,SH3BP5,SLC19A1,ACOX1,FAM3C,AEN,PARP10,YWHAH,GPATCH4,FAM129A,TRIM11,YTHDC2,SNX15,SND1,RUFY1,TRIM65,ZER1,KRR1,RAB8A,NUP210,NT5DC1,NOC2L,EIF5,TACC3,VPS13B,RYBP,PTPN18,MIOS,MBLAC2,CDC6,UTP3,ODC1,USP21,TRAM2,FBXO28,BCL7C,ARRDC1,ADAM9,DVL1,NUMB,ZNF564,C1orf74,CTU2,PARP12,ZCCHC9,CENPF,LAMTOR3,CHCHD2,NCKAP1,RSAD1,TNS3,SUB1,RINL,SSBP3,KIF13B,MBD2,XPA,AHCY,GLE1,MRPL48,LRSAM1,HDHD2,NTPCR,NSDHL,AMD1,CAMSAP1,ZNF761,STYXL1,APPL1,BBS12,RXRB,SDHB,PCM1,GALNT2,TMEM168,NLRC5,MYO9A,BTBD10,CCNB2,USP7,GLT8D1,SUCLG1,ARID2,TMX4,SLC2A1,ATP6V1B2,LYN,BCAP31,VAV1,MRPL50,PSMA6,ZNF473,ZNF302,BRPF3,TARDBP,BCAP29,CTDSP2,PRPF19,PPIF,KDM3B,MND1,CLCN3,BIRC3,RAB7A,ANKRD33B,PPIE,CHMP2B,VDAC1,EIF3H,TMEM201,GLOD4,IDE,DHX16,UHRF2,XRCC3,CHMP4B,PARD3,BCL2L12,KLHL21,PDAP1,TMX3,CDCA8,GTF3A,SLC12A9,TUBGCP2,HOMER1,WBP1L,POLR1B,RBM15B,PPAN,RHOA,RPRD1A,BTAF1,TOP3A,ARHGEF12,PCGF1,DDX23,RAB18,CACNB1,PDCD6,ATP6V1D,L3MBTL3,NEIL3,CTBS,BBX,IMPDH1,TAF12,NR2F2,HIPK3,IFI16,TXN,NUP188,PNISR,PRKCSH,USP39,UBE2I,SLC25A37,ASPHD2,ZNF428,RAB4A,TRA2B,SUCLG2,TAF5L,CISD2,ZNF800,CDC5L,ZNF524,SGCE,OSBP2,NSUN2,USP22,CLNS1A,EIF3A,ZMYM3,DOT1L,IWS1,ANKRD10,WAS,KIF18B,TPP2,C1orf109,ZMAT3,B4GALT2,PRPF38B,RECQL,C9orf78,EWSR1,RRM1,ACAP1,B4GALT1,FAM136A,SUPT7L,TMEM165,NPLOC4,CNOT3,WDR48,SPAG5,RTKN,CEP104,EXOSC7,KLHL5,LRRC8D,MSH2,PIGG,FBXL7,OSTF1,MRPL40,SYTL3,FAM171A1,APOL1,GCC2,PRIM2,ELL2,RDH10,MFNG,RPS24,GORASP2,CAPZA2,ADRB2,CCT8,MTR,PHF6,PFDN5,SLCO4A1,TTC13,GOLGA2,RBMX,MED15,PIAS2,APPL2,SAMD8,NUDT3,CDKN2A,ZNF511,ATXN3,RAF1,KIAA0232,C2orf49,CD320,EPM2A,CCNA2,MTMR4,TP53BP2,AQR,RBM12B,ILKAP,CDK12,BRD4,NARF,LRRC8A,ELP4,PKMYT1,ASB13,TRIM28,SUPT16H,EIF3K,CHMP4A,CBWD1,ATF6,XRCC4,ADAM23,PRPF4B,NDUFS1,DEPDC1,MECP2,SECISBP2,HMG20A,WWP2,JAKMIP1,SLC25A36,CCNK,DNAJC8,ELP5,AXIN2,CITED2,JMJD4,KAT2A,TMEM126B,RABIF,ADSL,PACS1,BMS1,KCNQ1,OTUD3,ARSK,MACF1,KIF11,KLF6,COMMD4,SMAP2,FADD,MYO1F,CBX3,TMEM127,PPP1R11,WDR62,TAF6,ESPL1,PURA,DDB1,DEF6,FAM83G,UBL3,NAT9,LYRM4,GPR132,PTP4A3,BRIX1,MRPL19,ZNF696,SF3B2,PCYOX1L,CDC42,SYNM,GOT2,JAZF1,HADHB,RPF2,SLC35C2,CNNM3,CARM1,WDR41,LARS,ZCCHC10,CCDC138,LRBA,TMEM216,SUMF2,KMT2C,OGFR,ASF1B,RPL37,MAN2A2,EIF4ENIF1,NIP7,U2SURP,MIA2,ZNF268,VPS4A,ATP6V0E1,PPP1R2,PM20D2,XPNPEP3,LYAR,FAM89B,TRAFD1,SUGP2,EIF2A,SYVN1,ARHGAP15,MASTL,UAP1,NFIL3,FN3KRP,YWHAZ,CTSA,TMEM14A,TSEN15,ADNP2,TCF12,PRKAB1,MDH2,SMARCA4,ORC1,RRN3,UBXN2A,IARS,CD3EAP,KIF14,CS,CLTB,CSTF1,POU2AF1,UBQLN4,PGGT1B,SELPLG,SMU1,ATXN1,GLO1,OGDH,BICD2,CADM1,EDEM2,HERPUD2,TOLLIP,FANCE,MBD3,PDHX,RPS9,SURF4,DUS3L,ARNTL,ANP32E,FKBP5,CCDC125,ABCA1,PDCD2L,GCLM,RAE1,DCTN2,NUP54,CHIC2,PAWR,MXD4,DCUN1D4,PIP4K2A,XPR1,FERMT3,KIF5B,KLHL20,SEC24C,RRBP1,ARHGEF2,ANP32A,LDLRAD3,C12orf75,STAT3,MYO5A,TXNL1,DCAF6,FAM49B,TMEM39A,ATP2C1,RFFL,COG1,RCOR1,PRMT2,TFEB,LEMD2,UPF1,ELMO1,ZC3H7B,DTX4,ZMIZ1,HRAS,CCDC93,FGFR1OP,TMED7,PIGQ,CNTROB,PPP1R16B,MIS12,GSDMB,PDS5B,NUP153,SENP1,PGAP2,TMEM115,PLEKHM3,DCUN1D5,PLEKHF2,BRMS1,PWWP2B,TRIM47,WDR11,AXIN1,SMG9,TRIM52,LONP2,NDUFV2,PHF23,CERK,SLC4A2,EZH1,ITGB5,LMNA,DDX56,EIF2S2,FOXN2,CARS2,PRRC2A,C16orf72,RB1CC1,ZMYND11,PGS1,MYBL2,UHRF1BP1,MPG,MATR3,CYB5A,NCDN,SETD3,TEX30,CNOT6,NDE1,EGLN1,ANKRD27,PPP1R37,ABCA3,SARNP,IVNS1ABP,MON1B,TMEM97,NIT2,NUF2,ZNF267,TCF19,TMEM161B,KTN1,APP,PRKD3,CLUAP1,ATP2A2,UTP18,GRSF1,ZCCHC2,ANAPC7,RNF19A,FAM76B,CLN6,TMEM9,GCC1,RNF169,ADCY7,ATP6V1G1,ENPP4,RNPS1,CDCA2,FKBP3,GPR137,DDX17,CHCHD3,PEX5,CDC16,HIPK2,MBOAT1,TICAM1,PDXK,ZBTB11,ANXA6,TMBIM4,GMCL1,UBE4A,IL21R,ETS1,WRB,ZNF92,PNO1,CAPN2,ADD3,TTLL12,TPCN1,TMX1,HNRNPM,LDHB,PPP3CA,NUDT8,POLK,JTB,MTMR12,PDE3B,KIF18A,CCDC6,WNT5B,MAPK6,LY75,RGL1,PSAP,WDR76,IGBP1,FAF1,COX15,AGRN,THOC1,GNPDA1,GPBP1L1,PPP1R15B,CSNK2A1,GIT2,BIRC2,ATPAF1,DLG5,ABL2,XRCC2,ZFYVE27,MCMBP,PTPRK,CDC37,HARS,ESYT1,ANLN,RHEB,DPYSL3,TBC1D17,TIMM13,TONSL,NAGLU,ACTB,ZNF45,CTCF,ASAH1,DOCK11,CRLF3,ASXL2,LRRC14,NUS1,SLC27A4,MDFIC,MAML1,CYTH1,NQO2,UTP15,EIF2AK1,EIF4G2,ZDHHC3,MOSPD3,ITPRIPL1,CDC27,PRMT7,KCTD7,NDUFA5,CYLD,UGP2,COPE,ZADH2,GGPS1,RPAIN,RAD23A,ATP6V0B,PDK2,STRBP,DUS4L,SAP30L,SLC39A9,CLPTM1,RPL29,MTMR6,NFATC2,KDM1B,ARL5B,USP36,CCDC127,MRPL2,ATP1A1,CLK3,PSMD3,CEP55,NCOA1,SLC25A39,ZC3HC1,ZNF146,ATXN7L2,CDC40,GOLIM4,SMAP1,RRP15,DAP,SMC6,ARFIP2,NKRF,CHAC2,BZW2,WRNIP1,TMA7,SS18L1,CENPM,PTGES3,MLEC,ZNF202,PPWD1,FAM50B,RHOT2,NEU1,TPD52L2,GOLGA7,TWSG1,GLG1,FAM126A,RPS6KC1,UBE2C,PPCS,TMEM41B,ZDHHC8,PLXNA1,CCNB1,SLC20A1,COMMD6,POLR3K,ASAP2,SNUPN,CNPY4,PLCL2,TFG,SEH1L,ATG9A,MKI67,DDX20,AMDHD2,SLC17A5,GALNT7,CCNF,FOXRED1,RBM47,PTER,WDR4,DHTKD1,TRAF5,HDAC2,HSPH1,LIME1,MAPRE1,CHTF18,KIF23,SLC35B1,NOTCH2,PMF1,FKBP1A,NDUFAF6,SLC31A1,SNX18,ATIC,CTPS1,ATP6V0A2,PIKFYVE,RNF135,LPCAT1,EEF1D,TMED2,PHF10,DDX28,ZNF84,FAM133B,RIT1,PLEC,KDM3A,SF3A2,FAS,EPRS,ZNF777,QARS,TCOF1,CABLES1,NRBP1,DNMT3A,RWDD1,CKLF,TRIP10,SF3B1,CAST,SUZ12,RPS6KA1,RAC1,GPR89A,OLA1,GNB2,FLAD1,APLP2,KDM2A,CDKN1B,TALDO1,GPX4,ATP13A1,RFC3,MAPRE2,ERF,CUL3,SLBP,KIAA1586,H2AFV,GAR1,POLG2,DHX57,NSA2,HSPA4,JAK1,TBL3,SEL1L,KLHDC4,B4GALT3,PDCD11,ATMIN,POLQ,POU3F2,OTUD5,NCOR2,PKP4,BABAM1,SLC25A12,BLM,TMCC3,GTF2F1,RPL17,CRAT,AHSA1,PRC1,UPF2,COPS7B,SLC38A10,CNOT6L,UBE2M,ZFP64,DENND4C,RPL8,ILF3,LRRC1,RHOT1,MARK2,ECH1,PLD3,NUCB1,FBXO21,GNA12,C1orf131,PRDX3,HNRNPH3,TFDP1,STX18,KHSRP,ASNA1,CPEB2,SSSCA1,VPS29,BYSL,S100PBP,MIB2,NOP2,UBN1,DCAF15,NF1,ALKBH5,MOGS,UBE2Z,TAF6L,BECN1,MAPK14,SNAPC4,RNF103,BCAT2,MBD4,METTL14,ZNHIT6,IMPAD1,RCSD1,PHTF1,SRI,KIF22,ZBTB22,NFU1,OGG1,TRIM14,COPS8,FYTTD1,TRIM8,RRM2,SOX4,ABHD5,UBTF,CXXC4,PAF1,UEVLD,SPATA2,IARS2,ATXN2L,GALNT10,STARD3NL,RPS15,PIGN,AGTRAP,CIB1,XPO7,SRRT,ZNF449,CAPZA1,GLTP,KIFAP3,BCL2,N4BP2,HP1BP3,VOPP1,THNSL1,ISG15,CAND1,GNAS,TSC1,RBM25,CDCA5,ZFP90,NANP,RBBP4,ZBTB24,MBD1,WASF2,MMACHC,TOMM20,GNPNAT1,MPHOSPH8,HNRNPUL2,CHD1,MEAF6,CCDC50,AKAP8,PARL,RPN2,CHTOP,F2R,FAM3A,SCYL3,ABI1,RLIM,FAM172A,ZNF500,PSMB7,NLN,WIPF1,BUD13,NDUFB1,PEF1,BTBD1,TAB2,CHCHD1,TULP3,WDR59,CANT1,SCARB1,GAS2,USP11,SMURF1,TSPAN5,CDS2,EYA1,CDK2AP2,MRPS26,KLF13,RGS1,HDDC2,MAN1A1,FBXO5,GART,TANK,PELO,BRD7,MRPL11,SAMD4B,ZDHHC18,WDR81,MEN1,ZNF407,MFN2,ZRANB2,SRSF3,MBD6,IDH3B,TATDN1,TSC2,LACTB2,ZNF275,ANKRD39,CDKN2C,USF1,NAPG,AP1M1,MECR,UPRT,CRY2,ECD,RNF26,TIPARP,RHBDD2,MGAT5,BAK1,RHOBTB3,ZNF559,GABPA,WBP1,ARF4,KRIT1,AHNAK,RAD18,RNASEL,CHPF2,OAZ1,PDCD4,NXT2,HIVEP3,KIAA0100,CLSPN,RHOC,DHX9,HAUS2,COPB2,CD59,TFAP4,RIMS3,MEGF8,EFTUD2,MRPL21,LUC7L2,EIF3L,MTA2,TYW1,USP10,ITM2A,SSR2,MTX1,SFXN5,FNTA,PDLIM1,TXNDC16,MRPL3,ALS2,FAM72A,TRIM41,KARS,NQO1,POC1A,ANK3,PTTG1,TPX2,TBC1D13,DAZAP2,GLRX3,REPS1,CBWD5,ABHD16A,FBXL6,SH3BP1,MTA1,UBA5,CLCN6,INTS12,RPRD1B,CPNE1,FAM118B,GOPC,E2F3,CIRBP,RPL38,CRNKL1,PFKFB3,GORAB,RAB1A,GIGYF1,TMEM184C,PPP2CA,KIF2A,RNF38,DMWD,USP13,MZT1,ZFP91,TRMT6,IP6K2,WDR5,IFT27,NEIL2,RRP36,SRXN1,RPA2,PSMD2,CLIC4,PDCD10,CBWD2,ITGB8,ARF5,ARHGEF1,FBXL19,GTF2H2,UTP20,MAGT1,GPS2,CD81,TMEM131,FANCI,PAPOLA,CREM,FANCL,TET3,GLIS2,IL6ST,INTS1,SLC44A1,MTPN,ASB6,PLK1,CELSR2,SEPT9,RBX1,APH1A,ZBED5,CKAP2L,UBE2V1,EAF2,IL12RB1,KRTCAP2,LUC7L,LSG1,NECAP2,C1orf122,TRIM4,AGPAT2,CHD3,ZNF367,PRPF4,KPNA2,BEND6,CLN3,FAM208A,NGLY1,POT1,MYL12B,CCDC137,RMND5A,HJURP,PHB2,DNAJB2,FAM53C,NKD2,SDC2,KLC1,CDK13,ADCK5,COX4I1,DNAJB1,RAB6A,ARID1B,C1GALT1,UBE2Q2,CCP110,ZNF746,ARL6IP1,CTR9,NIPSNAP1,ABHD2,DCAF8,ACSL3,LDB1,MAP4K3,NMT2,IRF5,HAUS8,MBIP,ZDHHC7,SIL1,FAM122A,DTD1,UNC13C,BCCIP,SART1,TRAF7,NDUFAF2,TOR1AIP1,ZNF416,TM9SF3,ZFYVE21,RRAGC,ZNF121,OIP5,NRF1,WDR44,PPME1,EFCAB11,RPAP1,CABLES2,LMAN1,AHCYL1,TOP1MT,STRAP,SPSB3,ZNF583,SNX25,ARHGAP17,POLR2G,ZNF780B,PPT1,NUP155,DCLRE1C,MRPS14,RHBDF2,SUGP1,RBL1,UBXN2B,STK38,AP1S1,SPRYD4,SLC22A23,H3F3A,CHID1,SMAD4,SLC30A9,CMAS,UNK,NADSYN1,HMGN3,NCAPG,SCYL2,FZD6,HERC3,CTSS,ORC3,RNLS,YTHDC1,ACP2,CSRP1,METTL5,TUFM,RANGAP1,PNPLA8,API5,ZFR,SEC23IP,E2F1,TMEM219,USP20,RBPJ,PDCD6IP,MAX,GXYLT1,LUZP1,ADAM10,CXXC1,TSC22D3,AP3M2,CUL1,GYG1,NANS,OAT,MYEF2,ANKRD26,PA2G4,NOL11,ZNF200,SLC26A2,SRP72,KLF10,LACTB,CBFB,RFC2,RAB2B,PRIM1,LUC7L3,MAP4,MRPL27,PTPDC1,NMD3,CCDC59,PTOV1,DNAJC5,SCOC,POLR2K,ANKH,PRKAA1,VAV2,C16orf87,TATDN3,DLGAP4,PXMP2,PSEN1,ZNF79,PDXDC1,YY1AP1,C12orf10,FAM192A,RPN1,LHX8,ARPC5,ZNRF2,TPST1,DAPK1,CYC1,SOCS5,FDFT1,PIGT,EMB,ZNF574,EXOSC9,ARID1A,PTTG1IP,FXR1,GOSR1,MAP2K2,TWISTNB,AKAP1,XRCC5,PI4K2A,CAT,DERL1,HSPBP1,MTHFD2,ARAP1,USP32,FAM83D,CABIN1,SMPD4,GPI,CYTIP,RAB11B,SLC39A13,POMP,BCL2L1,NUDT19,DECR1,RALB,ADCY9,LPIN2,MRPS27,SOCS6,TTC3,RNASEH2A,ANKLE2,CDC123,OAF,VDAC2,ERC1,ANKZF1,RAD51C,ZNF282,DSN1,HINT1,DGCR8,SAFB,RWDD4,LMBR1,NCLN,BEND3,EYA2,DYNC1LI2,MANBA,B4GALT5,SLC41A1,FAM76A,TKT,CBLL1,ARGLU1,LANCL1,POFUT1,FAM8A1,HEATR5B,HLA-A,EBP,RFWD3,FUT8,BTF3L4,PTPN11,MRPL54,FEM1B,RPL19,CNN2,NDUFA3,MTX2,MSH6,RFXANK,FBXO9,GUF1,ZHX1,OAZ2,NDUFS5,WDR91,HIGD2A,POLA2,ZNF76,MTX3,COPA,UQCR10,PHRF1,HMGXB3,ABCB10,DST,RAB35,SIVA1,GPATCH1,TCEA1,DRAM2,DEAF1,SNRNP200,LAP3,NCK1,VHL,SREK1,ARHGDIB,HSPB11,BRWD1,PPM1G,SH3GLB2,CRCP,BAZ1B,STK11,CLU,CHEK2,ZSWIM3,TSTD2,MRPL13,DCAF5,CAPN1,UBE2D3,NSMCE4A,PPP1R12A,ZCCHC8,NACA,UBXN1,C19orf25,PCSK7,EPN1,THRAP3,QSOX2,TTF1,NUP205,PRPF18,CHKA,DTL,MED10,ZRANB1,SLC12A2,ATP6V0D1,CSNK1G3,CREG1,NUDT4,VKORC1,SLTM,EVC2,SLC16A1,EHD4,CHMP2A,CORO7,FEZ2,UCK2,PMS2,UCK1,EXT2,MXD1,USP5,HNRNPA2B1,SAP130,NVL,CYB5R1,ZNF770,EBAG9,RNF25,PCGF6,FAM72B,PON2,HNRNPR,STAT6,HPS5,MAPK1,BRD9,PDF,TMEM33,DNAJC2,TRIP12,SHPRH,SCYL1,VPS45,MYO9B,GFM2,SPPL2A,FASTKD3,FGFR3,MZT2A,PPIG,H2AFY,ATG13,ERI3,FBL,SLC35A1,FRMD8,MICAL3,TGFB1,TIMMDC1,HELB,PSPC1,SCFD2,NDRG3,CDK11A,MEGF9,ACAT1,CENPT,PLOD3,RAB3IL1,ZSWIM6,RAB14,ADD1,KDM4A,MRPS15,XIAP,DHX8,GLUD1,ANKRD23,PABPC4,PSMD1,NEK6,NSRP1,RABGAP1L,SRSF4,FNIP2,KCNAB2,PCBP2,PLK3,MCL1,PPFIA3,SMC2,ICMT,SLC50A1,STOML2,ZNF689,LIMK1,PRDX5,ATE1,MLYCD,ST3GAL2,ATP6V0C,FBXL3,E2F2,AAAS,PFKP,DDX42,SSRP1,MRPS2,STRN4,TOP2B,ZNRF3,TMED3,RAVER2,GNS,INTS7,INPP5A,MCM5,PHF14,ZNF326,UBE2QL1,ETV3,DHX29,TEX10,MAN1B1,RPS10,CBFA2T2,RHOB,LRRC14B,DTWD1,PTPRF,SCARB2,OSBPL11,CCDC86,SLAIN1,HEXA,RNF139,SNX14,ZNF296,TRERF1,UBR2,CHD1L,ACTR3,WDTC1,MYH9,CREBL2,NIPA2,PRKACA,SAFB2,STAM,ANKIB1,ARL6IP6,RAB21,SP100,ZKSCAN1,DDA1,NUP107,ANKRD13C,MAVS,CEP63,TMEM136,ATF2,RBM15,DCTN1,SHOC2,PSRC1,MAP4K4,ATP6V0A1,NUSAP1,NDUFA7,DNAJA1,TAF2,C19orf54,SEC61A1,RPLP1,WDR7,CBLN2,FUS,LRP8,COIL,LRCH1,GALK1,ZNF786,SESTD1,TRAK1,AKT1S1,KRI1,FBXO3,GATC,NDUFB4,PPP1R8,PRDM4,GTSE1,DCP1A,SGCB,S100A6,IMPA2,NUDC,PDPK1,TK1,GUK1,TNFAIP3,GALC,ZNF512,KIAA0930,MRPS10,RPA1,ZNF180,ZNF862,KEAP1,POLE,TATDN2,CAPN7,LRPPRC,PML,USF2,ANAPC4,DDX47,MCCC1,CDC42SE2,S1PR2,CDIPT,SEC16A,SSR1,LIN9,PCNA,TRMU,ETV6,PIK3R2,PPCDC,TXLNA,MYBL1,CCAR1,MRPL32,ABCC5,BAZ2A,PBXIP1,TLK1,EZR,LNX2,LRP5,BRCA1,PRKRA,STX16,EPB41,OPTN,SOCS4,QRSL1,PIEZO1,GLCCI1,NUDT11,NAA60,GEMIN7,SEPHS2,LZTR1,RACGAP1,PPP3CB,B4GALT4,RLF,RAPGEF6,RB1,VASP,MED8,VMP1,PPIL2,TIMELESS,AHDC1,ALDH18A1,TMEM8A,ABCC1,TRAPPC9,AACS,MEMO1,KRAS,RTF1,UBE4B,NFATC2IP,ARPC1A,ZNF174,PSMC4,GOLGA4,SYNCRIP,PALB2,PRPS2,NIPA1,TIGD2,RNF114,FOXM1,MRPL39,XAB2,SUMO2,DUSP22,COMMD8,RPL11,CSDE1,MDM2,CORO1A,MINPP1,METTL9,POC5,DVL2,GM2A,PSMA8,COQ10B,CPOX,TIGD5,SLC26A6,CYP20A1,PRPF3,TXNL4A,RPSA,SRSF1,DNAJC10,ZNF700,SCAP,PLEKHG4B,TIMM17A,LTA4H,USP53,INTS2,CTDP1,MIF4GD,CDT1,ARID5A,SUMF1,CSNK1A1,AP3S1,PTPN2,IRF4,NDUFV1,SLC1A4,CWC27,SLC35B4,DDX31,ABCD1,RPAP3,CNTN5,SNX2,ZMYM5,CCDC34,CHCHD6,BSDC1,CDKN2AIPNL,FBXO41,KPNA4,BIRC5,TFE3,SNAP29,CDCA7L,PKD2,ACADM,CHMP7,SAT2,ZNF496,TAP1,YTHDF3,NHLRC3,IKBIP,ELMOD2,KIFC1,DBNDD1,PARPBP,CDC25B,DNMT1,NOL12,ORAI2,USO1,AKT2,NOL8,GNG7,AURKB,SLC25A5,ZFAND5,STT3A,TMED10,EIF2D,ITGB1,PTPN7,UQCRH,ARRB2,RTN3,ZNF598,DDX58,WSB2,PPIB,MUT,GMFG,HLA-E,MAN2B1,METTL3,CFLAR,NDUFS4,RNF121,MEX3C,HDAC7,DAD1,BDH1,PCYT2,GNAI2,ANKHD1,TERF2,MORC3,KCTD20,SEPT8,DCTD,PKM,PATL1,ADSS,ZFP92,NSF,DCK,ERGIC3,ACLY,LPCAT4,VCPIP1,PPP6R3,MAP3K5,PPP6R2,YY1,CDK2,RNF14,ZC3HAV1,SYS1,ZBTB37,URB2,EIF3D,MAGED1,KLHL18,ADPGK,SLC25A44,AP1B1,SDHA,PAIP2,PHC2,CRKL,TERF2IP,MOAP1,ZNF75D,SHC1,UCHL5,NAA35,TMBIM1,CDKN2AIP,CCT2,MKLN1,LYRM1,GALK2,CDC23,SHCBP1,AP4E1,PRDM11,VEZF1,PPP2R5A,ACYP1,STAT1,PPA2,TRIM32,RHEBL1,C1orf112,TCF3,MRI1,BRAP,AGPAT3,MYNN,SDF2L1,SPR,RAB11A,REEP5,FOXO3,MAD2L2,RBM17,MAT2B,PTEN,CENPJ,TAGLN2,OSTC,CREB1,NCOA2,PACS2,SMC4,NEK7,NET1,PARP4,TBRG4,ANAPC2,YIF1A,SGSH,HGS,TTLL4,SLC38A7,MFAP1,CCDC69,BRWD3,ESYT2,SKA3,NPHP4,UBE2E2,HNRNPAB,PLXNC1,ST13,TMEM184B,DNAJC24,ZNF107,SLC29A1,KIF2C,AGFG1,SIRT2,USP48,SNRPD3,UBQLN2,CUTC,EDC3,ZNF804A,RAP1A,THADA,EIF4A3,AP3S2,ATG3,DPYSL2,PPP1R12C,AKR1B1,JOSD1,NDUFB9,RP2,TTC4,TECR,ARID4A,FGFR1OP2,TIMM50,TDP1,DPM1,FOPNL,SLC16A7,SLC25A22,STK17B,DHX15,CHAF1A,GEMIN5,COPS6,SASS6,PSMC1,SLC12A7,TBC1D12,TM9SF4,ZNF768,MED13L,TIA1,MEF2A,EPHX2,RHBDD1,NFATC3,BANF1,BUD31,ZNF335,YBX1,KNTC1,UBE3C,ACAD8,ZNF189,ALDH9A1,KDELR1,TSTA3,CIC,OXR1,SEPT7,NAP1L1,EXOC4,NUP62,PITPNA,KIAA1328,NAA20,PTDSS1,MZT2B,PDSS2,C7orf26,IMMT,ASH1L,CHERP,WDYHV1,IRF3,PAIP1,ANKRD28,FARSA,ANKLE1,APOOL,PDIA6,ACSL5,TOR1AIP2,AZI2,RAD54B,TMEM41A,DAP3,ZNF317,AKNA,CBX4,KIF3B,GOLPH3L,SH2D3A,CASP6,TOR3A,SRGN,DBF4,CTNNBL1,YIF1B,TTC17,GINS1,CSNK1G2,TELO2,HMGN1,ADAM17,NASP,ASPM,PPP1R21,PRKAR1B,SYMPK,TARS,SNRPA,MAPK3,HSPA1B,HLA-B,PLAA,ATAD2,ZNF330,OSBPL8,KBTBD7,PREPL |
| 3.094e-02 | -3.48 | MYO1D (myosin ID) | protein interactions | 4642 | 42 | 12 | 17029 | 2761 |
COX15,SHC1,PTEN,EID1,ZNF746,PELO,DAPK1,CUL1,TOR1AIP2,PPP6R2,SSSCA1,PSMC4 |
| 3.094e-02 | -3.48 | CHMP2A (charged multivesicular body protein 2A) | protein interactions | 27243 | 42 | 12 | 17029 | 2761 |
CHMP2A,DECR1,ERLIN1,E2F4,SNAP23,RAB7A,RRBP1,CHMP4B,OSTF1,VPS4A,CHMP2B,TFG |
| 3.094e-02 | -3.48 | Strn3 (striatin, calmodulin binding protein 3) | protein interactions | 94186 | 42 | 12 | 17029 | 2761 |
MOB4,PPP2CA,CCT2,PDCD10,STRIP1,STRN4,TKT,SLC27A4,SIKE1,KPNA2,CCT8,FGFR1OP2 |
| 3.094e-02 | -3.48 | SYNE2 (spectrin repeat containing nuclear envelope protein 2) | protein interactions | 23224 | 42 | 12 | 17029 | 2761 |
PML,BRAP,NDUFB9,PRPF4,MAPK1,ARRB2,SDHA,TERF1,MAPK3,CDC37,TERF2,MORC3 |
| 3.094e-02 | -3.48 | POLR3C (RNA polymerase III subunit C) | protein interactions | 10623 | 42 | 12 | 17029 | 2761 |
SUB1,POLR2L,SUCLG1,GADD45B,CRCP,SMARCA4,POLR3GL,RANGAP1,CEP63,ROCK1,APP,POLR3K |
| 3.094e-02 | -3.48 | SCP2 (sterol carrier protein 2) | protein interactions | 6342 | 42 | 12 | 17029 | 2761 |
SUGP1,RAB8A,PEX5,SEPT9,PDRG1,ACOX1,RRBP1,VDAC2,RBMS1,PITPNA,NDUFA7,MYO5A |
| 3.094e-02 | -3.48 | ABL2 (ABL proto-oncogene 2, non-receptor tyrosine kinase) | protein interactions | 27 | 42 | 12 | 17029 | 2761 |
OIP5,CAT,ABL2,MDM2,HSPBP1,JAK1,TRIP10,NCK1,SIVA1,STAT3,HRAS,CDC37 |
| 3.094e-02 | -3.48 | WAKABAYASHI_ADIPOGENESIS_PPARG_RXRA_BOUND_WITH_H4K20ME1_MARK | MSigDB lists | WAKABAYASHI_ADIPOGENESIS_PPARG_RXRA_BOUND_WITH_H4K20ME1_MARK | 130 | 28 | 17377 | 2626 |
CYTH1,IMMT,FAM49B,BAZ2A,ACSL3,CERK,AP3S1,REEP5,PLEKHF2,BCAT2,TMCC3,PRNP,CHCHD3,SCARB2,PEX5,AGPAT2,LRRC8D,ACOX1,TANK,CS,PARL,XRCC3,ACADM,CHPT1,LONP2,GCSH,DRAM2,TMEM33 |
| 3.094e-02 | -3.48 | DARWICHE_SKIN_TUMOR_PROMOTER_UP | MSigDB lists | DARWICHE_SKIN_TUMOR_PROMOTER_UP | 130 | 28 | 17377 | 2626 |
SRM,FTL,COX5B,H2AFZ,TCTEX1D2,DYNLL1,SMU1,GBA,LDHA,KLF13,NUF2,LY6E,STX16,EXT2,EML4,RAB2B,SRSF1,CHKA,CAPN2,MAN2A2,IDE,LTBP4,ARAP1,CITED2,UBE2C,PGAM1,CHPT1,ATP6V0D1 |
| 3.094e-02 | -3.48 | DnaJ | smart domains | SM00271 | 47 | 12 | 9493 | 1367 |
DNAJC2,DNAJC10,DNAJC8,DNAJC5,DNAJB2,DNAJC17,DNAJC24,DNAJC9,DNAJA1,DNAJB1,DNAJC30,DNAJB9 |
| 3.100e-02 | -3.47 | GSE45365_HEALTHY_VS_MCMV_INFECTION_CD11B_DC_UP | MSigDB lists | GSE45365_HEALTHY_VS_MCMV_INFECTION_CD11B_DC_UP | 158 | 33 | 17377 | 2626 |
UNK,CORO7,EWSR1,SH2D3A,CHERP,DHX9,ALKBH5,THRAP3,POFUT1,HAUS2,HEATR5B,PAPOLA,ANKLE1,MEX3C,HDAC7,PPIL2,TRMU,XRCC2,ZFYVE27,MAP3K14,CNNM3,UBQLN4,CYTH1,DDX28,TELO2,ZNF559,PRKDC,PACS1,MEF2D,TBL3,CABIN1,TCOF1,ZNF75A |
| 3.104e-02 | -3.47 | COPI-independent Golgi-to-ER retrograde traffic | REACTOME pathways | R-HSA-6811436 | 28 | 9 | 10287 | 1696 |
RAB18,GALNT2,DYNLL1,DCTN2,AGPAT3,BICD2,RAB6A,DYNC1LI2,DCTN1 |
| 3.108e-02 | -3.47 | Clat_adaptor_s | pfam domains | PF01217 | 17 | 6 | 17054 | 2545 |
AP1S1,AP3S1,AP2S1,AP3S2,AP1M1,AP3M2 |
| 3.108e-02 | -3.47 | Cyclin_C | pfam domains | PF02984 | 17 | 6 | 17054 | 2545 |
CCNK,CCNA2,CCNL2,CCNF,CCNB1,CCNB2 |
| 3.112e-02 | -3.47 | GO_ENDONUCLEASE_ACTIVITY | MSigDB lists | GO_ENDONUCLEASE_ACTIVITY | 119 | 26 | 17377 | 2626 |
RPP25,ERCC1,RNASEH2C,PMS2,DCLRE1C,NEIL2,EDC3,MBD4,RAD51C,DGCR8,TATDN2,PPP1R8,NEIL3,RNASEK,XRCC2,PELO,POP7,XRCC3,RNASEH2A,RNASEL,TATDN1,GEN1,N4BP2,OGG1,TSEN15,RAD51D |
| 3.113e-02 | -3.47 | Betaine Metabolism | SMPDB pathways | SMP00123 | 8 | 4 | 992 | 167 |
MAT2B,AHCY,MTR,MAT2A |
| 3.113e-02 | -3.47 | Transfer of Acetyl Groups into Mitochondria | SMPDB pathways | SMP00466 | 8 | 4 | 992 | 167 |
MDH1,MPC1,ACLY,CS |
| 3.114e-02 | -3.47 | - | gene3d domains | 3.30.1220.10 | 5 | 3 | 8148 | 1295 |
CBWD1,CBWD2,CBWD5 |
| 3.114e-02 | -3.47 | - | gene3d domains | 2.40.290.10 | 5 | 3 | 8148 | 1295 |
RBM15,XRCC5,RBM15B |
| 3.114e-02 | -3.47 | - | gene3d domains | 2.20.70.30 | 5 | 3 | 8148 | 1295 |
BTF3,NACA,BTF3L4 |
| 3.115e-02 | -3.47 | haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-Langerhans_cell_histiocytosis | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-Langerhans_cell_histiocytosis | 61 | 15 | 17385 | 2587 |
GNAS,FGFR3,RB1,EWSR1,NRAS,PTEN,VHL,PTPN11,ATP6V0A1,STK11,KRAS,HRAS,SMAD4,MAK16,CDKN2A |
| 3.115e-02 | -3.47 | Langerhans_cell_histiocytosis | COSMIC cancer mutations | Langerhans_cell_histiocytosis | 61 | 15 | 17385 | 2587 |
GNAS,FGFR3,RB1,EWSR1,NRAS,PTEN,VHL,PTPN11,ATP6V0A1,STK11,KRAS,HRAS,SMAD4,MAK16,CDKN2A |
| 3.118e-02 | -3.47 | ESCRT-III complex | KEGG pathways | M00412 | 12 | 5 | 7161 | 1149 |
CHMP2A,CHMP4B,CHMP4A,CHMP2B,CHMP7 |
| 3.118e-02 | -3.47 | RNA polymerase I, eukaryotes | KEGG pathways | M00182 | 12 | 5 | 7161 | 1149 |
POLR1B,POLR2L,POLR2K,ZNRD1,TWISTNB |
| 3.118e-02 | -3.47 | ESCRT-III complex | KEGG pathways | hsa_M00412 | 12 | 5 | 7161 | 1149 |
CHMP2A,CHMP4B,CHMP4A,CHMP2B,CHMP7 |
| 3.118e-02 | -3.47 | RNA polymerase I, eukaryotes | KEGG pathways | hsa_M00182 | 12 | 5 | 7161 | 1149 |
POLR1B,POLR2L,POLR2K,ZNRD1,TWISTNB |
| 3.120e-02 | -3.47 | REACTOME_LOSS_OF_NLP_FROM_MITOTIC_CENTROSOMES | MSigDB lists | REACTOME_LOSS_OF_NLP_FROM_MITOTIC_CENTROSOMES | 55 | 14 | 17377 | 2626 |
PLK1,FGFR1OP,MAPRE1,PCM1,CENPJ,DYNLL1,DCTN2,SSNA1,CEP63,PRKACA,HAUS2,TUBB,CSNK1D,DCTN1 |
| 3.120e-02 | -3.47 | MODULE_350 | MSigDB lists | MODULE_350 | 55 | 14 | 17377 | 2626 |
CLPTM1,PLD3,NUCB1,ABCA3,EWSR1,FOXM1,RAB24,SDC2,MON1B,FAM89B,TMED3,SNRNP70,TAF6,RPRD1B |
| 3.123e-02 | -3.47 | large_cell_carcinoma | COSMIC cancer mutations | large_cell_carcinoma | 862 | 148 | 17385 | 2587 |
MAX,CSNK2A1,MAPK14,EEF2K,CDKN2C,CDK5,ABL2,NUP210,NOL11,NEK6,CYB5RL,INTS1,IL6ST,PPCDC,TFG,SRPK2,CDC5L,PLK1,PLK3,SGCE,NRAS,AKT2,VHL,PBK,LRBA,TLK1,AURKB,STK17B,MAP3K4,AHNAK,CHD3,LIMK1,STK11,RNASEL,CHEK2,TM9SF4,UBXN1,PRKAA1,TRIO,KLC1,CDK13,ADCK5,EIF2AK4,RB1,CEP104,ATIC,DAPK1,ANKHD1,ATP6V0D1,PHKG2,CSNK1G3,SUGP2,RTF1,MAP4K3,EIF2AK1,KRAS,PLEC,ARID1A,MAP2K2,DAPK3,MASTL,GNAS,GOLGA4,ORMDL2,QARS,APPL2,CTSA,MAP3K5,CDK2,PDSS2,NRBP1,MRPL3,CDKN2A,EXOC3,DNMT3A,TP53RK,ARID2,RAF1,SUZ12,RPS6KA1,SF3B1,TPX2,SMARCA4,SLC35B2,PRKACA,LYN,TWF2,CSDE1,DECR1,PRKD3,PDK2,KIF14,RPAP1,INTS12,CDK12,SCYL3,BRD4,GOPC,MAP4K4,PKMYT1,BUD13,TRIM28,EML4,TMEM184C,JAK1,CLK3,FASTK,HIPK2,STK38,SEL1L,MAPK1,SMAD4,PRPF4B,TMEM33,RRP15,SCYL1,TCF3,MYO9B,CSNK1A1,POFUT1,SCYL2,ZNF92,KIF5B,FGFR3,NDUFB4,PTEN,HUWE1,CAMK2G,PDPK1,CSNK1G2,ZFP64,TNFAIP3,ASPM,NEK7,METTL5,LDHA,MARK2,SYMPK,MAPK3,KEAP1,CCDC6,MAPK6,ATP6V1C1,PLOD3,ZMIZ1,RPS6KC1,HRAS,HIPK3 |
| 3.123e-02 | -3.47 | lung-carcinoma-large_cell_carcinoma | COSMIC cancer mutations | lung-carcinoma-large_cell_carcinoma | 862 | 148 | 17385 | 2587 |
MAX,CSNK2A1,MAPK14,EEF2K,CDKN2C,CDK5,ABL2,NUP210,NOL11,NEK6,CYB5RL,INTS1,IL6ST,PPCDC,TFG,SRPK2,CDC5L,PLK1,PLK3,SGCE,NRAS,AKT2,VHL,PBK,LRBA,TLK1,AURKB,STK17B,MAP3K4,AHNAK,CHD3,LIMK1,STK11,RNASEL,CHEK2,TM9SF4,UBXN1,PRKAA1,TRIO,KLC1,CDK13,ADCK5,EIF2AK4,RB1,CEP104,ATIC,DAPK1,ANKHD1,ATP6V0D1,PHKG2,CSNK1G3,SUGP2,RTF1,MAP4K3,EIF2AK1,KRAS,PLEC,ARID1A,MAP2K2,DAPK3,MASTL,GNAS,GOLGA4,ORMDL2,QARS,APPL2,CTSA,MAP3K5,CDK2,PDSS2,NRBP1,MRPL3,CDKN2A,EXOC3,DNMT3A,TP53RK,ARID2,RAF1,SUZ12,RPS6KA1,SF3B1,TPX2,SMARCA4,SLC35B2,PRKACA,LYN,TWF2,CSDE1,DECR1,PRKD3,PDK2,KIF14,RPAP1,INTS12,CDK12,SCYL3,BRD4,GOPC,MAP4K4,PKMYT1,BUD13,TRIM28,EML4,TMEM184C,JAK1,CLK3,FASTK,HIPK2,STK38,SEL1L,MAPK1,SMAD4,PRPF4B,TMEM33,RRP15,SCYL1,TCF3,MYO9B,CSNK1A1,POFUT1,SCYL2,ZNF92,KIF5B,FGFR3,NDUFB4,PTEN,HUWE1,CAMK2G,PDPK1,CSNK1G2,ZFP64,TNFAIP3,ASPM,NEK7,METTL5,LDHA,MARK2,SYMPK,MAPK3,KEAP1,CCDC6,MAPK6,ATP6V1C1,PLOD3,ZMIZ1,RPS6KC1,HRAS,HIPK3 |
| 3.126e-02 | -3.47 | GO_REGULATION_OF_MITOCHONDRIAL_OUTER_MEMBRANE_PERMEABILIZATION_INVOLVED_IN_APOPTOTIC_SIGNALING_PATHWAY | MSigDB lists | GO_REGULATION_OF_MITOCHONDRIAL_OUTER_MEMBRANE_PERMEABILIZATION_INVOLVED_IN_APOPTOTIC_SIGNALING_PATHWAY | 40 | 11 | 17377 | 2626 |
BAK1,SIVA1,DYNLL1,TFDP1,E2F1,PPP3R1,YWHAZ,BCL2,TP53BP2,SLC25A5,YWHAH |
| 3.126e-02 | -3.47 | PID_IFNG_PATHWAY | MSigDB lists | PID_IFNG_PATHWAY | 40 | 11 | 17377 | 2626 |
CRKL,PTPN2,RAP1A,JAK1,STAT1,PTPN11,DAPK1,STAT3,MAPK1,CAMK2G,MAPK3 |
| 3.126e-02 | -3.47 | GO_4_IRON_4_SULFUR_CLUSTER_BINDING | MSigDB lists | GO_4_IRON_4_SULFUR_CLUSTER_BINDING | 40 | 11 | 17377 | 2626 |
SDHB,NDUFV1,NDUFS1,POLE,PRIM2,TYW1,NDUFS8,NFU1,RSAD1,NDUFS7,TYW1B |
| 3.126e-02 | -3.47 | MODULE_453 | MSigDB lists | MODULE_453 | 40 | 11 | 17377 | 2626 |
GNS,ZBTB10,KIF14,BTAF1,INTS1,VAV2,ANP32E,CCNF,SHCBP1,FKBP3,APP |
| 3.127e-02 | -3.47 | CAVIN1 (caveolae associated protein 1) | protein interactions | 284119 | 101 | 24 | 17029 | 2761 |
CCDC93,MAX,RPRD1A,RAB7A,DHX9,ILF3,RCOR1,NUF2,PSMD9,TTF1,GIT2,HMG20A,OIP5,TRIM26,FBXO28,RAD18,TMED10,GRIPAP1,SNAP29,RABGAP1L,KLHL15,ARNTL,MBOAT1,TERF2 |
| 3.127e-02 | -3.47 | RCC1 (regulator of chromosome condensation 1) | protein interactions | 1104 | 101 | 24 | 17029 | 2761 |
SUZ12,SF3B6,CDK2AP2,NUSAP1,RANGAP1,PKM,UBE2I,CSNK1A1,GNB2,RPA1,CHKA,FLAD1,KPNA4,LUC7L3,PPM1G,NUP107,HADHB,H2AFY,KMT2B,ACTB,NUP153,RBPJ,FAF1,HNRNPM |
| 3.134e-02 | -3.46 | positive regulation of protein binding | biological process | GO:0032092 | 86 | 20 | 17256 | 2622 |
MAPRE1,ADD1,FLOT1,MFNG,MEN1,PSEN1,PARK7,APP,KRIT1,EPB41,RPL11,DERL1,FKBP1A,PPP2CA,CDK5,RALB,HIPK2,TICAM1,PLCL2,NMD3 |
| 3.134e-02 | -3.46 | ERBB signaling pathway | biological process | GO:0038127 | 86 | 20 | 17256 | 2622 |
PDPK1,TGFB1,ADAM17,PTPN18,NRAS,REPS2,KRAS,ERBIN,CPNE3,ARF4,ABL2,SHC1,RPS27A,CSK,PTPN11,MVP,MAPK1,HRAS,CDC37,SOCS5 |
| 3.137e-02 | -3.46 | Translation Factors | WikiPathways | WP107 | 53 | 14 | 5312 | 837 |
EIF5A,EIF2S2,EIF3D,GSPT2,EIF2AK1,EIF5,EIF4H,EIF3G,PABPC1,EIF3H,PAIP1,EIF3A,EEF1D,EEF2K |
| 3.137e-02 | -3.46 | RANBP9 (RAN binding protein 9) | protein interactions | 10048 | 132 | 30 | 17029 | 2761 |
GID8,RMND5A,UNK,NCOR2,MKLN1,PIGT,MPHOSPH8,RAF1,DCTN2,USP42,RNPS1,NFATC2,BRCA1,FXR1,CDK11B,UBE2I,PRKACA,ARMC8,APP,TFRC,LMNA,RAB8A,SMAD2,HIPK2,MAPK6,ITGB1,DDX5,USP11,DDB1,DCTN1 |
| 3.137e-02 | -3.46 | apoptotic mitochondrial changes | biological process | GO:0008637 | 65 | 16 | 17256 | 2622 |
MOAP1,BAK1,PPIF,GCLM,NDUFS1,ATG3,JTB,MCL1,BCL2,CLU,BCL2L1,RHOT1,ATF2,RHOT2,EYA2,TIMM50 |
| 3.139e-02 | -3.46 | V$RFX1_02 | MSigDB lists | V$RFX1_02 | 250 | 49 | 17377 | 2626 |
GGNBP2,ANKRD13D,ZNF768,CDK2AP2,TMX4,STRN4,AP3M2,KLHL18,EBNA1BP2,DCUN1D4,PRKACA,GNB2,ABHD14A,CRKL,USF1,RPL17,PIN1,SLC44A1,PHTF1,RNF5,NUDC,PBXIP1,TSPYL4,PPP1R21,HSDL1,HNRNPF,E2F3,POLR3GL,C14orf132,DNAJA1,CADM1,PLEC,THNSL1,KDM3A,DHX57,STOML2,HMGN2,CHCHD3,ETS2,TMED10,DUSP3,ELMO1,SPATA2,STX18,E2F1,SH3GLB2,AP1S1,PTPDC1,RNF139 |
| 3.142e-02 | -3.46 | PCI | prosite domains | PS50250 | 23 | 7 | 12060 | 1670 |
COPS8,EIF3K,COPS7B,EIF3L,PSMD8,PSMD3,EIF3A |
| 3.144e-02 | -3.46 | MACF1 (microtubule-actin crosslinking factor 1) | protein interactions | 23499 | 66 | 17 | 17029 | 2761 |
EIF5A,USP7,MAPRE1,CSRP1,CUL3,MYH9,CAPZA2,MCM2,GOLGA4,SYNCRIP,HUWE1,SNAP29,CEP63,PDIA6,SRPK2,CDC5L,TERF2 |
| 3.144e-02 | -3.46 | PPP4C (protein phosphatase 4 catalytic subunit) | protein interactions | 5531 | 66 | 17 | 17029 | 2761 |
PPP2CA,CCT2,TK1,CCDC6,PPME1,PPP4R1,CUL3,WDR81,GEMIN4,PLOD3,IGBP1,PPP2R2D,CCT8,TRIM28,CAND1,PRPF19,CDC5L |
| 3.144e-02 | -3.46 | TAF15 (TATA-box binding protein associated factor 15) | protein interactions | 8148 | 66 | 17 | 17029 | 2761 |
POLR2G,SUZ12,CUL3,CUL1,BRCA1,MCM2,MATR3,POLR2A,RPA1,CAND1,RPA2,SCARB2,SAFB,TAF12,FUS,COPS6,DDB1 |
| 3.144e-02 | -3.46 | EXOSC5 (exosome component 5) | protein interactions | 56915 | 66 | 17 | 17029 | 2761 |
DECR1,PA2G4,EXOSC6,EXOSC7,PSMA6,NUP210,POLR2L,GOLGA2,TBL3,EXOSC1,CUL3,PSMA1,EXOSC9,OGDH,PKM,BIRC2,RPL36 |
| 3.144e-02 | -3.46 | POLR3A (RNA polymerase III subunit A) | protein interactions | 11128 | 66 | 17 | 17029 | 2761 |
RPAP3,EWSR1,RAE1,TUFM,POLR3GL,SMARCA4,ASB13,POLR3K,POLR2A,MRPL2,RPAP1,MRPL54,CRCP,POLR1B,RUVBL2,MRPL11,HDAC2 |
| 3.145e-02 | -3.46 | GO_DNA_TEMPLATED_TRANSCRIPTION_INITIATION | MSigDB lists | GO_DNA_TEMPLATED_TRANSCRIPTION_INITIATION | 198 | 40 | 17377 | 2626 |
NAT14,RORB,CCNC,POLR2K,THRAP3,TAF6L,NOTCH2,TTF1,GTF2F1,RRN3,MED8,MED10,CD3EAP,POLR1B,MAML1,GTF2H2,ZNRD1,POLR2I,POLR2L,POLR2G,POLR2D,E2F3,POLR3GL,RTF1,TRIM28,POLR2A,TWISTNB,MAPK3,RXRB,TAF2,UBTF,POLR2J,TBPL1,CRCP,TAF12,RBPJ,ZNF45,E2F2,TAF6,NRBP1 |
| 3.147e-02 | -3.46 | deoxyribonucleotide metabolic process | biological process | GO:0009262 | 35 | 10 | 17256 | 2622 |
GUK1,DUT,RRM1,TBPL1,RRM2,DCTD,OGG1,HDDC2,NEIL2,MBD4 |
| 3.147e-02 | -3.46 | positive regulation of histone methylation | biological process | GO:0031062 | 35 | 10 | 17256 | 2622 |
PAF1,KMT2E,MECP2,OGT,CTR9,RTF1,BRCA1,CHTOP,DNMT1,SMAD4 |
| 3.147e-02 | -3.46 | response to ischemia | biological process | GO:0002931 | 35 | 10 | 17256 | 2622 |
PPIF,TIGAR,ABRAXAS2,CIB1,MLYCD,BCL2,MAP3K5,ARID1B,RNLS,EEF2K |
| 3.151e-02 | -3.46 | Cyclin_C-dom | interpro domains | IPR004367 | 17 | 6 | 18492 | 2768 |
CCNK,CCNA2,CCNL2,CCNF,CCNB1,CCNB2 |
| 3.151e-02 | -3.46 | AP_mu_sigma_su | interpro domains | IPR022775 | 17 | 6 | 18492 | 2768 |
AP1S1,AP3S1,AP3S2,AP2S1,AP3M2,AP1M1 |
| 3.153e-02 | -3.46 | GO_PROTEIN_COMPLEX_LOCALIZATION | MSigDB lists | GO_PROTEIN_COMPLEX_LOCALIZATION | 50 | 13 | 17377 | 2626 |
EXOC3,PCM1,MZT1,MIOS,BIRC5,KLHL21,DYNLL1,EZR,SSNA1,IFT27,IFT46,SEH1L,BBS12 |
| 3.153e-02 | -3.46 | KLEIN_PRIMARY_EFFUSION_LYMPHOMA_UP | MSigDB lists | KLEIN_PRIMARY_EFFUSION_LYMPHOMA_UP | 50 | 13 | 17377 | 2626 |
ALG3,NCOR2,IRF4,ATP2A2,AGPAT2,SELPLG,ILF3,PTP4A3,RPN2,GPI,LTA4H,BCAP31,ZMYM3 |
| 3.153e-02 | -3.46 | REACTOME_GOLGI_ASSOCIATED_VESICLE_BIOGENESIS | MSigDB lists | REACTOME_GOLGI_ASSOCIATED_VESICLE_BIOGENESIS | 50 | 13 | 17377 | 2626 |
FTL,SNX2,DNM2,AP1M1,AP1S1,TGOLN2,ARF1,AP1B1,AP4E1,AP3S1,PICALM,TFRC,SNAPIN |
| 3.153e-02 | -3.46 | GO_CELLULAR_CARBOHYDRATE_BIOSYNTHETIC_PROCESS | MSigDB lists | GO_CELLULAR_CARBOHYDRATE_BIOSYNTHETIC_PROCESS | 50 | 13 | 17377 | 2626 |
UGP2,RPS27A,AKT2,IMPAD1,SLC2A1,AKR1B1,B4GALT1,NANS,GYG1,EXT2,PHKG2,IMPA2,EPM2A |
| 3.155e-02 | -3.46 | GGGTGGRR_V$PAX4_03 | MSigDB lists | GGGTGGRR_V$PAX4_03 | 1223 | 208 | 17377 | 2626 |
CCDC93,PTMS,MAX,ADD1,WDR13,ZDHHC8,YTHDF3,UBE2Z,CSNK2A1,MIS12,SLC25A37,C14orf119,PA2G4,DPYSL2,RAD23B,AP1M1,MAST2,MCMBP,ZNF800,FGFR1OP2,TRIM8,KLF10,BAZ2A,PBXIP1,TLK1,ZBED5,HNRNPF,LRP5,ARHGDIB,WBP1,KRTCAP2,ZFAND5,CBFB,LUC7L,DHX15,KRIT1,HHEX,AHNAK,EIF4ENIF1,SMAD2,BRD2,MAP4,MYO18A,SH3GLB2,ST3GAL2,ATP6V0C,ROCK1,ZSWIM3,RTN3,B4GALT2,GEMIN7,UBE2D3,LIME1,PHF23,CTCF,HAUS4,MAN2B1,THRAP3,RAB6A,NOTCH2,XPO7,DOCK11,RTKN,FBRS,MCTS1,SLC38A5,RNFT1,SSBP3,MEA1,FAM89B,TNPO3,RBM3,KNTC1,GNAI2,PHKG2,LUC7L2,EIF5A,LDB1,MAP4K3,UBE4B,MTX1,PLEC,SYVN1,SEPT7,ARMC8,KDM3A,EIF4G2,NCDN,PTPRF,MAGED2,SYNCRIP,CSK,ODF2,YWHAZ,TOB1,ADNP2,WASF2,ZNF296,TRIM41,CYLD,TRERF1,RAB11B,ZBTB37,CAST,MAGED1,RAC1,HCFC1R1,ZADH2,BCAP31,GNB2,RAD23A,SAP130,HNRNPA2B1,CCNA2,SHC1,RALB,UTP18,SH3BP1,DDA1,CS,CLCN6,TNPO2,CDKN1B,CORO1A,ATF2,CDK12,ABI1,CFL1,DCTN1,RLIM,KDM3B,BRD4,POLR2L,ERF,LYRM1,TAOK1,ATXN1,TOR1AIP2,CDCA2,MEF2D,CADM1,OGDH,RAB1A,TAZ,MBD3,POLG2,GIGYF1,SRSF1,DDX17,MRPL2,PPP2R5A,HNRNPR,RBL1,TAB2,STAT6,GADD45B,ZNF436,H2AFX,RNF38,REEP4,ZBTB11,RHEBL1,OTUD5,SLC41A1,SRSF6,ZFP91,CBLL1,ARFIP2,KLF13,SIKE1,AP3S1,RAB11A,EBP,FBXO5,FBXO3,KIF5B,HOMER1,ADD3,PDCD10,ARF5,FUT8,ARHGEF1,H2AFY,ARHGEF2,DDX31,ABCD1,ATG13,COPS7B,ZNF710,STAT3,SPTAN1,PPP1R9B,RPRD1A,RHOA,ZNF512,HEBP2,ARHGEF12,WDR81,PICALM,MARK2,MAPK3,CBX3,TMEM127,CACNB1,FAM110A,OAZ2,BRWD3,USF2 |
| 3.158e-02 | -3.46 | TYK2 (tyrosine kinase 2) | protein interactions | 7297 | 96 | 23 | 17029 | 2761 |
CEP170B,CCT2,TK1,KLF10,SLC2A1,MIER2,IL12RB1,LYN,CCT8,TRIM28,XRCC5,JAKMIP1,CRKL,VAV1,JAK1,SIVA1,IL6ST,STAT1,SIAH2,DNM2,DDX5,RUVBL2,LRP8 |
| 3.158e-02 | -3.46 | VDR (vitamin D receptor) | protein interactions | 7421 | 96 | 23 | 17029 | 2761 |
NCOR2,PRKCSH,NKD2,CSNK2A1,HMGN3,BRCA1,THRAP3,CDK11B,FOXO3,MXD1,POLR2A,MAPK3,RXRB,PPP2CA,RB1,MDM2,CDCA7L,STAT1,AFF1,NCOA1,RNF14,MAPK1,NCOA2 |
| 3.158e-02 | -3.46 | PID_RHOA_PATHWAY | MSigDB lists | PID_RHOA_PATHWAY | 45 | 12 | 17377 | 2626 |
RHOA,PPP1R12A,CDC42,PTEN,LIMK1,ITGB1,CDKN1B,EZR,ROCK1,ATF2,CFL1,PIP5K1C |
| 3.158e-02 | -3.46 | GO_POSITIVE_REGULATION_OF_ORGANELLE_ASSEMBLY | MSigDB lists | GO_POSITIVE_REGULATION_OF_ORGANELLE_ASSEMBLY | 45 | 12 | 17377 | 2626 |
PDCD6IP,SEPT9,RALB,STX18,PIP4K2C,KCTD17,CNOT6,SEPT7,CNOT6L,LRSAM1,PIP4K2A,SH3GLB1 |
| 3.158e-02 | -3.46 | GO_OXIDOREDUCTASE_ACTIVITY_ACTING_ON_A_SULFUR_GROUP_OF_DONORS | MSigDB lists | GO_OXIDOREDUCTASE_ACTIVITY_ACTING_ON_A_SULFUR_GROUP_OF_DONORS | 45 | 12 | 17377 | 2626 |
TXNL1,GSTK1,DNAJC10,TXN,PRDX3,TMX3,GLRX3,GFER,QSOX2,TMX1,PCYOX1L,SRXN1 |
| 3.158e-02 | -3.46 | TCTAGAG,MIR-517 | MSigDB lists | TCTAGAG,MIR-517 | 45 | 12 | 17377 | 2626 |
FEZ2,MAGED1,METTL5,ILF3,CUL3,CS,TNPO2,FAM122A,ARGLU1,RBM3,HMGN3,FBRS |
| 3.164e-02 | -3.45 | Signaling by Insulin receptor | REACTOME pathways | R-HSA-74752 | 322 | 66 | 10287 | 1696 |
PRKAB1,TSC2,NF1,RAF1,RRAGC,ATP6V1B2,EEF2K,CALM2,ATP6V0B,RAP1A,PSMD1,PSMA6,SHC1,PIK3R2,MLST8,ATP6V1G1,NRAS,PSMA8,RBX1,AKT2,CUL3,PSMB7,ATP6V0A1,PSMB9,RHEB,PPP2CA,PPP2R5A,JAK1,RPS27A,PSMD8,PSMD3,CAB39,ATP6V0C,STK11,PPP5C,ARRB2,MAPK1,PSMC1,ATP6V0E1,PRKAA1,LAMTOR3,BRAP,AKT1S1,PSMD9,PSMD2,FGFR3,PTPN11,ATP6V0A2,ATP6V0D1,CAMK2G,SPTAN1,PDPK1,PSMA1,KRAS,PDE3B,MAP2K2,PSMB3,MAPK3,PSMC4,TSC1,ATP6V1D,CSK,LAMTOR4,KBTBD7,ATP6V1C1,HRAS |
| 3.165e-02 | -3.45 | ACACTGG,MIR-199A,MIR-199B | MSigDB lists | ACACTGG,MIR-199A,MIR-199B | 147 | 31 | 17377 | 2626 |
TXNL1,RORB,ATXN3,PARP12,PPP1R2,ZFP91,WDTC1,MYH9,ARGLU1,ARID1A,ETS1,MYEF2,CDC73,FZD6,AKAP1,CREM,KPNA4,RBM47,WDR44,HIPK2,CDCA7L,ZCCHC2,RAD23B,RNF38,PIK3IP1,TSPAN5,NCOA2,ALS2,SMARCD1,ABCC5,FUBP1 |
| 3.165e-02 | -3.45 | GSE37301_HEMATOPOIETIC_STEM_CELL_VS_PRO_BCELL_DN | MSigDB lists | GSE37301_HEMATOPOIETIC_STEM_CELL_VS_PRO_BCELL_DN | 147 | 31 | 17377 | 2626 |
CMAS,RPL29,POLR2I,ZMYND11,MRI1,EIF3D,ARHGDIB,PMF1,ICAM2,CDK11B,LSG1,EIF3H,RPL23A,MAGED2,CACNB1,PDCD6,CTNNBL1,HINT1,SSBP3,COX7A2L,APPL2,NFU1,NAP1L4,NANP,REEP4,IGBP1,RPS26,EYA2,TMEM9,PDCD4,EEF1D |
| 3.165e-02 | -3.45 | CTCTGGA,MIR-520A,MIR-525 | MSigDB lists | CTCTGGA,MIR-520A,MIR-525 | 147 | 31 | 17377 | 2626 |
TSHZ1,NCOR2,PPP1R9B,SNX27,FAM53C,ZFP91,ARID5A,SLC26A6,KLF13,YTHDF3,ATXN1,SEPT7,METTL22,GNB2,MXD1,USP5,RB1,THADA,PTEN,ZNRF2,STAT6,PPP3R1,OGT,TNPO2,PPP6R3,CLTB,UBE2C,MAPK1,ATF2,SEH1L,CAMK2G |
| 3.173e-02 | -3.45 | SMAD4 (SMAD family member 4) | protein interactions | 4089 | 239 | 50 | 17029 | 2761 |
RHOG,MAX,EWSR1,DNAJB2,UBE2Z,CTCF,MEF2A,IRF3,EIF2AK4,UBE2I,FOXO3,HMG20A,CD59,NEK6,EIF4A3,DCP1A,AP2B1,TENM3,ATF2,ILKAP,CAMK2G,NRAS,PBK,PRKAR1B,ZBED5,BRCA1,ERBIN,CYFIP2,ARL5B,RAB2B,ISG15,HGS,SMAD2,RPS27A,RBL1,TFE3,PIAS2,UHRF2,DVL1,YY1,SNRNP70,ZMIZ1,SMAD1,MAPK1,SMURF1,TOB1,SMAD4,PARD3,CSNK1D,RHEBL1 |
| 3.177e-02 | -3.45 | Notch signaling | KEGG pathways | hsa_M00682 | 16 | 6 | 7161 | 1149 |
ADAM17,NOTCH2,RBPJ,PSEN1,APH1A,APH1B |
| 3.177e-02 | -3.45 | N-glycan biosynthesis, complex type | KEGG pathways | M00075 | 16 | 6 | 7161 | 1149 |
MAN2A2,B4GALT1,B4GALT3,MGAT5,FUT8,B4GALT2 |
| 3.177e-02 | -3.45 | N-glycan biosynthesis, complex type | KEGG pathways | hsa_M00075 | 16 | 6 | 7161 | 1149 |
MAN2A2,B4GALT1,B4GALT3,MGAT5,FUT8,B4GALT2 |
| 3.177e-02 | -3.45 | Notch signaling | KEGG pathways | M00682 | 16 | 6 | 7161 | 1149 |
ADAM17,NOTCH2,RBPJ,PSEN1,APH1A,APH1B |
| 3.180e-02 | -3.45 | FOXP3 (forkhead box P3) | protein interactions | 50943 | 71 | 18 | 17029 | 2761 |
ZBTB37,SUGP2,NFATC2,SMC2,CDC23,ZFR,WRNIP1,NRF1,SMC3,CDC27,SIVA1,HDAC7,AKAP8,ZNF326,NUP107,BEND3,USP11,HDAC2 |
| 3.180e-02 | -3.45 | CEP192 (centrosomal protein 192) | protein interactions | 55125 | 71 | 18 | 17029 | 2761 |
ZBTB10,CYLD,MAGED1,USP42,CNTROB,KDM1B,ANKRD28,KIF2A,PCM1,SPATA2,CENPJ,ODF2,SIL1,CEP63,RBM12B,SASS6,EYA2,POC5 |
| 3.180e-02 | -3.45 | PPP4R3A (protein phosphatase 4 regulatory subunit 3A) | protein interactions | 55671 | 71 | 18 | 17029 | 2761 |
AMPD2,TELO2,XAB2,MTA2,CAST,EHMT1,USP10,MCM2,MAPK14,POLR2A,FKBP1A,FBXO28,HUWE1,CCDC6,HNRNPR,PPME1,NSFL1C,IGBP1 |
| 3.180e-02 | -3.45 | SUPT6H (SPT6 homolog, histone chaperone) | protein interactions | 6830 | 71 | 18 | 17029 | 2761 |
WSB2,CSNK2A1,NFATC2,BRCA1,HAUS2,POLR2A,WDR48,IWS1,TBC1D22A,H2AFX,CTR9,ANAPC7,TCEA1,PDCD11,MCPH1,RPRD1B,STRAP,SSRP1 |
| 3.180e-02 | -3.45 | STK4 (serine/threonine kinase 4) | protein interactions | 6789 | 71 | 18 | 17029 | 2761 |
MOB4,KIF3B,FGFR1OP,STRIP1,TAOK1,STRN4,KIF2C,AURKB,MAP1LC3B,FOXO3,ERC1,KIF2A,RAB8A,H2AFX,SH3GLB2,MOB1A,FGFR1OP2,CDC37 |
| 3.180e-02 | -3.45 | PSMD10 (proteasome 26S subunit, non-ATPase 10) | protein interactions | 5716 | 71 | 18 | 17029 | 2761 |
RHOA,LDB1,LMNA,UBLCP1,PSMC4,WWP2,PTPN2,PSMD2,RB1,HSPA4,PSMD1,MDM2,GRSF1,PSMD3,PSMD8,UCHL5,PSMC1,EEF1D |
| 3.180e-02 | -3.45 | GSE3720_VD1_VS_VD2_GAMMADELTA_TCELL_UP | MSigDB lists | GSE3720_VD1_VS_VD2_GAMMADELTA_TCELL_UP | 181 | 37 | 17377 | 2626 |
MCM10,MRPL42,NDUFAF2,PHRF1,FAM53C,CTCF,PXMP2,AGFG1,LYAR,SEC11A,PPP1R8,MCM5,BANF1,TPST1,GEMIN6,MRPL21,MRPL11,EIF5,STRAP,PPA1,TMEM14C,EIF5A,COPS8,YTHDC1,ERF,DHX29,NSUN2,DNAJC9,MAK16,TSR2,CBX3,RPA1,TIMM13,POLE,PRDX3,LRPPRC,BAZ1B |
| 3.180e-02 | -3.45 | GSE24634_TEFF_VS_TCONV_DAY5_IN_CULTURE_DN | MSigDB lists | GSE24634_TEFF_VS_TCONV_DAY5_IN_CULTURE_DN | 181 | 37 | 17377 | 2626 |
UBL3,NAT9,ANK3,ACAP1,KLF13,CHKB,EZH1,DAZAP2,EPHX2,MOAP1,CLUAP1,INPP5A,RABGAP1L,TTC3,PLCL2,FAM171A1,SPSB3,ATP6V1G1,CYTH1,PGS1,ZMYND11,MAN1B1,SRSF5,PRMT2,ICAM2,KLF6,EIF3G,NMT2,RXRB,MAGED2,PEX5,SERF2,ZNF45,USP11,PPP2R2D,PDCD4,RNF114 |
| 3.180e-02 | -3.45 | GSE41867_DAY6_VS_DAY8_LCMV_CLONE13_EFFECTOR_CD8_TCELL_UP | MSigDB lists | GSE41867_DAY6_VS_DAY8_LCMV_CLONE13_EFFECTOR_CD8_TCELL_UP | 181 | 37 | 17377 | 2626 |
WASF2,PTMS,GLT8D1,WDR13,RHOC,AP3M2,CNTROB,LMNA,C14orf119,GOLM1,ZNF449,KIF13B,TIMELESS,MRPL40,CENPM,TALDO1,ENPP4,TRAFD1,TSPAN31,SLC25A22,PDE3B,PSMB9,DHX57,MYO1F,PI4K2A,HLA-B,HSPB11,PML,NLRC5,COX8A,TMEM219,RNASEL,WDR62,BEND6,IGBP1,MZT2B,ATP6V0E1 |
| 3.180e-02 | -3.45 | GSE40273_XBP1_KO_VS_WT_TREG_UP | MSigDB lists | GSE40273_XBP1_KO_VS_WT_TREG_UP | 181 | 37 | 17377 | 2626 |
WSB2,GOLPH3L,UGP2,GADD45G,RRM1,EIF2AK4,FKBP2,SUPT7L,REEP5,PRPF18,HDDC2,GSTK1,C1GALT1,PDXP,MCM5,ADCY9,BTF3L4,TIMELESS,INTS12,AQR,ZRANB1,TRIM14,FAM118B,PPIE,ITM2A,METTL22,STOML2,AMZ2,BRWD1,TWSG1,NSMCE2,CAB39,STK11,SMAD1,SASS6,GLCCI1,PSMC1 |
| 3.180e-02 | -3.45 | GSE5142_CTRL_VS_HTERT_TRANSDUCED_CD8_TCELL_EARLY_PASSAGE_CLONE_DN | MSigDB lists | GSE5142_CTRL_VS_HTERT_TRANSDUCED_CD8_TCELL_EARLY_PASSAGE_CLONE_DN | 181 | 37 | 17377 | 2626 |
DDX58,RPS2,SYS1,TM9SF4,UFC1,SNX15,ENSA,PDCD7,STMN1,ZADH2,APP,NDUFS4,APLP2,ADD3,GEMIN6,PIK3IP1,METTL9,PPP6R1,PCBP2,ABCC5,CSTF1,CSNK1G2,ORAI2,EMB,FRAT2,DIDO1,AZI2,SMAP2,RPSA,ADSS,SLCO4A1,KLHL15,IMPDH1,MBOAT1,PPP6R3,GPATCH4,CAPN1 |
| 3.180e-02 | -3.45 | GSE17301_IFNA2_VS_IFNA5_STIM_ACD3_ACD28_ACT_CD8_TCELL_UP | MSigDB lists | GSE17301_IFNA2_VS_IFNA5_STIM_ACD3_ACD28_ACT_CD8_TCELL_UP | 181 | 37 | 17377 | 2626 |
IER2,HECA,CDS2,AGRN,PPP1R2,CAST,FAM129A,ACTR3,GSPT2,CREBL2,COX4I1,IRF3,ADPGK,MOAP1,HOMER1,SLC31A1,AHCTF1,SP100,ARPC5,IL6ST,LPIN2,FAM89B,CTR9,PIK3IP1,SCYL3,PIP4K2C,MCL1,NDRG3,CDK11A,MAP3K4,FBXO21,CSK,ARNTL,NDE1,TMEM14A,PDCD4,ADAM23 |
| 3.182e-02 | -3.45 | PEX5 (peroxisomal biogenesis factor 5) | protein interactions | 5830 | 91 | 22 | 17029 | 2761 |
MYH9,BRCA1,EPHX2,ZADH2,ECH1,CAT,NUDT19,GSTK1,IDE,SNUPN,CCDC14,ACOX1,CRAT,PRDX5,MPV17,MLYCD,SCARB1,LONP2,POT1,S100A6,NUDT3,LDHB |
| 3.182e-02 | -3.45 | STK3 (serine/threonine kinase 3) | protein interactions | 6788 | 91 | 22 | 17029 | 2761 |
MOB4,PLK1,CPNE1,KIF3B,FGFR1OP,STRIP1,RAE1,RAF1,STRN4,GMCL1,KIF2C,AURKB,TAZ,MAP1LC3B,DST,ZNF420,QARS,KHSRP,MRPL40,MOB1A,FGFR1OP2,IFI16 |
| 3.184e-02 | -3.45 | COMT (catechol-O-methyltransferase) | protein interactions | 1312 | 33 | 10 | 17029 | 2761 |
RAB14,CDC27,NSDHL,PPA2,GBA,ESYT1,RGS2,VKORC1,TMX1,RDH11 |
| 3.184e-02 | -3.45 | DCAF4L2 (DDB1 and CUL4 associated factor 4 like 2) | protein interactions | 138009 | 33 | 10 | 17029 | 2761 |
HNRNPA2B1,COPS8,YBX1,COPS7B,COPS6,PABPC1,CCT8,DDB1,PRDX1,CFL1 |
| 3.184e-02 | -3.45 | PLTP (phospholipid transfer protein) | protein interactions | 5360 | 33 | 10 | 17029 | 2761 |
IMPAD1,FUT8,DDX31,ADPGK,GALNT7,DHFR2,TAZ,ABCA1,NMD3,RDH11 |
| 3.184e-02 | -3.45 | PHF10 (PHD finger protein 10) | protein interactions | 55274 | 33 | 10 | 17029 | 2761 |
TRIM26,CELSR2,VAV2,BCL7C,SMARCA4,ARID1A,FBL,SMARCE1,LUC7L,SMARCD1 |
| 3.184e-02 | -3.45 | CRNN (cornulin) | protein interactions | 49860 | 33 | 10 | 17029 | 2761 |
PA2G4,WDR59,NRM,NUP54,ANXA5,KRAS,NSD3,SND1,GPI,CDK11A |
| 3.184e-02 | -3.45 | BAZ1A (bromodomain adjacent to zinc finger domain 1A) | protein interactions | 11177 | 33 | 10 | 17029 | 2761 |
MAX,RHOA,SMAD2,MECP2,SUMO2,H2AFX,BAZ1B,RBBP4,SRPK2,XRCC5 |
| 3.184e-02 | -3.45 | HIST2H2AA3 (histone cluster 2 H2A family member a3) | protein interactions | 8337 | 33 | 10 | 17029 | 2761 |
GEMIN5,DNAJC2,MCM5,SUZ12,NOC2L,AURKB,MCM2,MEN1,USP21,APP |
| 3.184e-02 | -3.45 | ARL6IP4 (ADP ribosylation factor like GTPase 6 interacting protein 4) | protein interactions | 51329 | 33 | 10 | 17029 | 2761 |
SRSF11,USP7,PIP4K2C,CSNK2A1,JMJD6,ZRANB2,ETS1,PIP4K2A,DVL2,SRPK2 |
| 3.184e-02 | -3.45 | OGFOD1 (2-oxoglutarate and iron dependent oxygenase domain containing 1) | protein interactions | 55239 | 33 | 10 | 17029 | 2761 |
H2AFZ,GNPDA1,ATIC,EZR,AHCY,TWF2,SRRT,ASB6,MCTS1,RAD23A |
| 3.184e-02 | -3.45 | CKAP2 (cytoskeleton associated protein 2) | protein interactions | 26586 | 33 | 10 | 17029 | 2761 |
CEP104,PCM1,CENPJ,POC1A,AHSA1,KIF22,UBE2C,APP,MIS12,DCTN1 |
| 3.184e-02 | -3.45 | RAD17 (RAD17 checkpoint clamp loader component) | protein interactions | 5884 | 33 | 10 | 17029 | 2761 |
RFC3,POLE,CLSPN,PRKDC,H2AFX,TOP3A,USP20,CHEK2,RFC2,FOXO3 |
| 3.184e-02 | -3.45 | CPNE1 (copine 1) | protein interactions | 8904 | 33 | 10 | 17029 | 2761 |
CPNE1,TIMM13,PDCD6,ST13,ACTB,PPP5C,TTLL12,ARRB2,UBE2M,SDHA |
| 3.184e-02 | -3.45 | HDAC10 (histone deacetylase 10) | protein interactions | 83933 | 33 | 10 | 17029 | 2761 |
NCOR2,LETMD1,UQCRH,DNAJA1,MCM2,TRIM28,ABHD14A,HDAC2,PAPOLA,FDFT1 |
| 3.184e-02 | -3.45 | ETFB (electron transfer flavoprotein subunit beta) | protein interactions | 2109 | 33 | 10 | 17029 | 2761 |
STAU1,DSN1,PRKAR1B,LRPPRC,GMCL1,ADRB2,PITPNB,APP,EYA2,GPX4 |
| 3.187e-02 | -3.45 | MHC protein binding | molecular function | GO:0042287 | 30 | 9 | 17224 | 2647 |
DERL1,FAM49B,HLA-E,TAP1,TAP2,ATP5F1B,ATP5F1A,BCAP31,TUBB |
| 3.188e-02 | -3.45 | LISH | prosite domains | PS50896 | 28 | 8 | 12060 | 1670 |
GID8,RMND5A,FGFR1OP,TCOF1,MKLN1,FOPNL,SSBP3,SMU1 |
| 3.195e-02 | -3.44 | Keratan sulfate degradation | KEGG pathways | hsa_M00079 | 5 | 3 | 7161 | 1149 |
GNS,HEXA,HEXB |
| 3.195e-02 | -3.44 | Keratan sulfate degradation | KEGG pathways | M00079 | 5 | 3 | 7161 | 1149 |
GNS,HEXA,HEXB |
| 3.197e-02 | -3.44 | ZHU_CMV_24_HR_UP | MSigDB lists | ZHU_CMV_24_HR_UP | 92 | 21 | 17377 | 2626 |
EIF5A,POLR2K,HLA-E,IDH3A,TAP1,GMFB,GORASP2,MARK2,RAB2B,ISG15,SSR1,PSMD2,SCARB2,RB1,PSMA6,TRIM26,SAR1A,EIF5,ATP6V1C1,PSMC1,PFKP |
| 3.197e-02 | -3.44 | DE_YY1_TARGETS_DN | MSigDB lists | DE_YY1_TARGETS_DN | 92 | 21 | 17377 | 2626 |
CYLD,AGGF1,TACC1,WDR1,PRKAA1,RAB6A,CAPZA2,MACF1,FAS,DST,RB1,PRKD3,CLIC4,CDC27,PTEN,RBL1,HIPK2,TAGLN2,CSNK1G3,SMNDC1,SOCS5 |
| 3.197e-02 | -3.44 | Base Excision Repair | REACTOME pathways | R-HSA-73884 | 37 | 11 | 10287 | 1696 |
RPA2,PCNA,RFC3,POLE,PARG,MPG,RFC2,OGG1,NEIL2,MBD4,RPA1 |
| 3.197e-02 | -3.44 | Resolution of Abasic Sites (AP sites) | REACTOME pathways | R-HSA-73933 | 37 | 11 | 10287 | 1696 |
RPA2,PCNA,RFC3,POLE,PARG,MPG,RFC2,OGG1,NEIL2,MBD4,RPA1 |
| 3.198e-02 | -3.44 | POLR1A (RNA polymerase I subunit A) | protein interactions | 25885 | 86 | 21 | 17029 | 2761 |
RPAP3,POLR2L,POLR2K,TRIP10,SHPRH,CSNK2A1,BRCA1,TWISTNB,SUPT16H,UBTF,RRN3,CD3EAP,PDRG1,TCOF1,POLR1B,RUVBL2,ECD,USP11,ARRB2,ZNRD1,SSRP1 |
| 3.198e-02 | -3.44 | BRD4 (bromodomain containing 4) | protein interactions | 23476 | 86 | 21 | 17029 | 2761 |
RFC3,RPL6,SMARCA4,RTF1,JMJD6,NSD3,BRCA1,RFC2,PIP4K2A,RB1,FGFR3,RBM25,BRD2,PTEN,PTAR1,AFF1,YWHAZ,CHEK2,STAT3,BRD9,CDC5L |
| 3.199e-02 | -3.44 | NDC80 (NDC80, kinetochore complex component) | protein interactions | 10403 | 76 | 19 | 17029 | 2761 |
PLK1,WDYHV1,NUF2,AURKB,PMF1,CCNB1,MIS12,CCNK,RB1,HGS,PCM1,DSN1,MFAP1,TXLNA,TP53BP2,NDE1,SGF29,CDC5L,DCTN1 |
| 3.199e-02 | -3.44 | ATOH1 (atonal bHLH transcription factor 1) | protein interactions | 474 | 76 | 19 | 17029 | 2761 |
TCF12,PRKDC,TCF3,CPOX,AGO2,TUFM,PLEC,CSNK1A1,MACF1,KIF11,MAPK3,HUWE1,ACOX1,RBMX,AHSA1,SRI,PDXK,USP11,CSNK1D |
| 3.200e-02 | -3.44 | UBE2E1 (ubiquitin conjugating enzyme E2 E1) | protein interactions | 7324 | 127 | 29 | 17029 | 2761 |
USP7,H2AFZ,TRIM11,RNF25,XIAP,CUL3,ATXN1,TOPORS,BRCA1,UBE2I,CBWD5,TRIM28,RNF103,WWP2,DTL,RFWD3,PAF1,ZNRF2,DDA1,H2AFY,CTR9,TRIM32,RNF26,RNF14,LRSAM1,RNF5,RNF169,RNF114,RLIM |
| 3.200e-02 | -3.44 | FHL3 (four and a half LIM domains 3) | protein interactions | 2275 | 127 | 29 | 17029 | 2761 |
RBM42,SRGN,TMX3,UBE2Q1,UBE2I,PATL1,PLEKHF2,PHC2,ZBTB21,SMAD2,PPIG,MED15,MRPL27,PML,RBMS1,FAM122A,SLAIN1,ACTB,CDC25B,CORO1A,SNRPG,CREB1,MAPK1,CNNM3,ZNRD1,SMAD4,MRM3,CCAR1,RHEBL1 |
| 3.205e-02 | -3.44 | HNF4A (hepatocyte nuclear factor 4 alpha) | protein interactions | 3172 | 81 | 20 | 17029 | 2761 |
NCOR2,SUZ12,SMARCA4,UBE2I,PRKACA,EXT2,PABPC4,MAPK3,SUB1,MDM2,SMAD2,MED10,GPS2,MECR,NCOA1,H3F3A,TAF6,MAPK1,SMAD4,NCOA2 |
| 3.205e-02 | -3.44 | SGF29 (SAGA complex associated factor 29) | protein interactions | 112869 | 81 | 20 | 17029 | 2761 |
TCF12,KAT2A,KIF2C,SUPT20H,TAF6L,USP22,WDR5,SUPT7L,REPS1,C1orf122,KIF5B,MBIP,SNAP29,RABGAP1L,FAAP100,BUD31,TAF5L,TP53BP2,TAF12,ATXN7L2 |
| 3.205e-02 | -3.44 | PIAS2 (protein inhibitor of activated STAT 2) | protein interactions | 9063 | 81 | 20 | 17029 | 2761 |
MBD1,DNMT3A,SUMO2,CDCA8,ELK1,UBE2I,RUFY1,TSR2,PARK7,LMNA,GOLGA2,SIAH1,HUWE1,PML,SIAH2,PIAS2,CHMP4B,YWHAH,SMAD4,CDKN2A |
| 3.205e-02 | -3.44 | PID_P73PATHWAY | MSigDB lists | PID_P73PATHWAY | 76 | 18 | 17377 | 2626 |
PLK3,PLK1,BAK1,UBE4B,CCNB1,HAGH,MAPK14,FOXO3,FAS,PFDN5,RB1,CCNA2,MDM2,JAK1,PIN1,PML,AEN,CDK2 |
| 3.205e-02 | -3.44 | GO_MICROTUBULE_MOTOR_ACTIVITY | MSigDB lists | GO_MICROTUBULE_MOTOR_ACTIVITY | 76 | 18 | 17377 | 2626 |
KIF3B,KIF15,KLC1,KIF23,KIF2C,KIF11,KIF5B,KIF2A,KIFC1,STARD9,SMC3,KIF18A,KIF18B,KIF13B,KIF14,KIF22,DNAL4,DYNC1LI2 |
| 3.206e-02 | -3.44 | V$EGR_Q6 | MSigDB lists | V$EGR_Q6 | 262 | 51 | 17377 | 2626 |
RHOG,PTMS,CYLD,REPS2,TSC2,DLGAP4,KLF13,SLC25A12,CTCF,PPP3CB,HCFC1R1,AP3S1,PPP1R16B,CDC73,RAD23A,FBRS,CYHR1,APLP2,ITGB8,ARPC5,WDR44,OSTC,LMAN1,NAA35,UBE2M,LYPLA2,CLPTM1,PPP1R9B,PPP3CA,KLF10,OSBP2,ERF,MTA2,PACS1,PRPF3,WDR81,MATR3,CAND1,ADSS,UBTF,HHEX,HSPA4,BRD2,CORO1C,ERGIC3,PITPNA,ANP32E,RGL1,NR2F2,BRWD3,CBX4 |
| 3.206e-02 | -3.44 | positive regulation of DNA binding transcription factor activity | biological process | GO:0051091 | 249 | 49 | 17256 | 2622 |
DDX58,RWDD1,PHB2,TCF3,DHX9,CIB1,SMARCA4,UBE2I,PARK7,APP,JMY,CFLAR,DDRGK1,TERF2IP,PSMA6,PTEN,BUD31,ARHGEF2,MAVS,ATF2,MTPN,TRIM14,CARM1,DVL2,TGFB1,PPP3CA,TRAPPC9,TRIM8,RNF25,KRAS,UBE2V1,LRP5,ERC1,HSPA1B,CAT,TRIM26,TAB2,PRDX3,RPS27A,HIPK2,CEBPG,TICAM1,TRIM32,CLU,TRIM52,TAF12,TRAF5,LRP8,RHEBL1 |
| 3.207e-02 | -3.44 | HMG_BOX_2 | prosite domains | PS50118 | 49 | 12 | 12060 | 1670 |
UBTF,SP100,CIC,HMGXB3,BBX,WDHD1,HMGB2,PBRM1,SOX4,SMARCE1,HMG20A,SSRP1 |
| 3.231e-02 | -3.43 | protein phosphatase 2A binding | molecular function | GO:0051721 | 21 | 7 | 17224 | 2647 |
ANKLE2,BCL2,IGBP1,PPME1,STRN4,MASTL,ENSA |
| 3.235e-02 | -3.43 | AEBP2 (AE binding protein 2) | protein interactions | 121536 | 20 | 7 | 17029 | 2761 |
JMJD6,ATXN3,RBBP4,KMT5A,SUZ12,APP,KBTBD7 |
| 3.235e-02 | -3.43 | TMEM189 (transmembrane protein 189) | protein interactions | 387521 | 20 | 7 | 17029 | 2761 |
NADK2,SEPT11,NIT2,HGS,NDUFV1,RBM4,MAPK3 |
| 3.235e-02 | -3.43 | RBMXL2 (RNA binding motif protein, X-linked like 2) | protein interactions | 27288 | 20 | 7 | 17029 | 2761 |
CUL1,TRA2B,COX15,VDAC1,MCM5,CAND1,CUL3 |
| 3.235e-02 | -3.43 | Edc4 (enhancer of mRNA decapping 4) | protein interactions | 234699 | 20 | 7 | 17029 | 2761 |
DCP1A,AP2B1,EIF2AK4,PATL1,SGF29,EDC3,HADHB |
| 3.235e-02 | -3.43 | FAM84B (family with sequence similarity 84 member B) | protein interactions | 157638 | 20 | 7 | 17029 | 2761 |
XRCC3,CHEK2,NOTCH2,PALB2,SMAD4,UROD,NMT2 |
| 3.235e-02 | -3.43 | UNG (uracil DNA glycosylase) | protein interactions | 7374 | 20 | 7 | 17029 | 2761 |
RPA2,PPP2CA,UBE2E2,PCNA,APP,DDB1,RPA1 |
| 3.235e-02 | -3.43 | BCAM (basal cell adhesion molecule (Lutheran blood group)) | protein interactions | 4059 | 20 | 7 | 17029 | 2761 |
ATP6V0A1,TNPO2,ATP6V0A2,TNPO3,UBE2I,ARNTL,EPB41 |
| 3.235e-02 | -3.43 | EAF2 (ELL associated factor 2) | protein interactions | 55840 | 20 | 7 | 17029 | 2761 |
TCEA1,EAF2,RBBP4,ELL2,BIRC2,PIP4K2A,SIAH2 |
| 3.235e-02 | -3.43 | YTHDF3 (YTH N6-methyladenosine RNA binding protein 3) | protein interactions | 253943 | 20 | 7 | 17029 | 2761 |
RPA2,BRCA1,MCM2,POT1,ISG15,FAF1,RPA1 |
| 3.235e-02 | -3.43 | NR4A2 (nuclear receptor subfamily 4 group A member 2) | protein interactions | 4929 | 20 | 7 | 17029 | 2761 |
BAZ1B,SMARCA4,NCOR2,NCOA1,CREB1,RPS6KA1,RXRB |
| 3.235e-02 | -3.43 | BICD1 (BICD cargo adaptor 1) | protein interactions | 636 | 20 | 7 | 17029 | 2761 |
PLK1,RAB6A,PCM1,MAPK14,STAT3,DCTN2,DCTN1 |
| 3.235e-02 | -3.43 | CHCHD6 (coiled-coil-helix-coiled-coil-helix domain containing 6) | protein interactions | 84303 | 20 | 7 | 17029 | 2761 |
SLC25A12,CHCHD2,APOOL,ERLIN1,MTX2,APP,RAB7A |
| 3.235e-02 | -3.43 | TNK1 (tyrosine kinase non receptor 1) | protein interactions | 8711 | 20 | 7 | 17029 | 2761 |
GTSE1,YWHAZ,DDX5,SEC16A,YWHAH,MATR3,ILF3 |
| 3.235e-02 | -3.43 | TTI2 (TELO2 interacting protein 2) | protein interactions | 80185 | 20 | 7 | 17029 | 2761 |
RPAP3,SLC39A9,TELO2,FUS,HSPA4,RUVBL2,PRKDC |
| 3.235e-02 | -3.43 | DPPA2 (developmental pluripotency associated 2) | protein interactions | 151871 | 20 | 7 | 17029 | 2761 |
MOAP1,ZCCHC10,MCM10,PLOD3,PCGF1,PBXIP1,DVL2 |
| 3.235e-02 | -3.43 | AHSG (alpha 2-HS glycoprotein) | protein interactions | 197 | 20 | 7 | 17029 | 2761 |
DDX31,SNX27,VKORC1,CDC42,PPP5C,ATF2,MAPK6 |
| 3.235e-02 | -3.43 | ARF3 (ADP ribosylation factor 3) | protein interactions | 377 | 20 | 7 | 17029 | 2761 |
KIF23,ARFIP2,ARF1,GGA2,CLN3,GGA1,CDC73 |
| 3.235e-02 | -3.43 | SNX18 (sorting nexin 18) | protein interactions | 112574 | 20 | 7 | 17029 | 2761 |
ANKRD28,CUL1,CDC16,EWSR1,UBR2,SDC2,DNM2 |
| 3.235e-02 | -3.43 | ASB17 (ankyrin repeat and SOCS box containing 17) | protein interactions | 127247 | 20 | 7 | 17029 | 2761 |
ATP2A2,VDAC1,PHB2,ARF4,TUBB,SLC25A1,TUFM |
| 3.235e-02 | -3.43 | INCENP (inner centromere protein) | protein interactions | 3619 | 20 | 7 | 17029 | 2761 |
AURKB,EWSR1,H2AFZ,BIRC5,IFI16,CDCA8,FLOT1 |
| 3.235e-02 | -3.43 | Oxnad1 (oxidoreductase NAD-binding domain containing 1) | protein interactions | 218885 | 20 | 7 | 17029 | 2761 |
UBE3B,CCNL2,ERF,HNRNPH3,MIER1,TRIM14,PDF |
| 3.235e-02 | -3.43 | ARHGAP5 (Rho GTPase activating protein 5) | protein interactions | 394 | 20 | 7 | 17029 | 2761 |
PLK1,UNK,ADRB2,RHOA,PTPN18,SMURF1,ITGB1 |
| 3.235e-02 | -3.43 | SYBU (syntabulin) | protein interactions | 55638 | 20 | 7 | 17029 | 2761 |
KIF5B,ATXN1,RACGAP1,RPL29,MAPRE1,TRAF7,SNAPIN |
| 3.235e-02 | -3.43 | PHKA2 (phosphorylase kinase regulatory subunit alpha 2) | protein interactions | 5256 | 20 | 7 | 17029 | 2761 |
UBE3C,FOXK1,ARRB2,EYA2,PHKG2,RAF1,TUBGCP2 |
| 3.235e-02 | -3.43 | ATP1A2 (ATPase Na+/K+ transporting subunit alpha 2) | protein interactions | 477 | 20 | 7 | 17029 | 2761 |
RAB1A,VDAC1,ZNRF2,ATP6V0D1,VDAC2,CAND1,CUL3 |
| 3.235e-02 | -3.43 | TBX3 (T-box 3) | protein interactions | 6926 | 20 | 7 | 17029 | 2761 |
DCP1A,TOLLIP,CDCA5,HDAC2,PLEKHF2,MAPK3,PML |
| 3.235e-02 | -3.43 | LARS2 (leucyl-tRNA synthetase 2, mitochondrial) | protein interactions | 23395 | 20 | 7 | 17029 | 2761 |
SDHB,TGOLN2,MRPL21,SUCLG1,DUSP22,NDUFS7,GLMP |
| 3.237e-02 | -3.43 | TBK1.DF_UP | MSigDB lists | TBK1.DF_UP | 268 | 52 | 17377 | 2626 |
GOLPH3L,TMEM184B,ANXA6,TMEM41B,CIB1,CHIC2,TBC1D13,LANCL1,STAM,RNF103,FZD6,CREM,RB1,RAB21,TNS3,TNFAIP8,ADCY9,TPST1,CORO1A,TP53BP2,MINPP1,MYBL1,CAMK2G,GINS1,VOPP1,PHF10,GCC2,TNFAIP3,RAD51AP1,NUDT4,PIP4K2C,USP10,RABIF,EMP3,RIT1,TTC33,PLEKHF2,TRAM2,SERTAD2,ACYP1,LSM6,DUSP3,CCDC6,GOLGA8A,TFE3,SNAP23,NFIL3,DNAJC17,RNF38,TBPL1,GALNT10,PRPF4B |
| 3.237e-02 | -3.43 | V$E4F1_Q6 | MSigDB lists | V$E4F1_Q6 | 268 | 52 | 17377 | 2626 |
PKP4,TSC22D3,UFC1,TOR1AIP1,CDK2AP2,HABP4,SLC39A13,AGPAT1,RAB6A,USP48,UBQLN2,S1PR2,ZADH2,SLC25A37,WDR48,HNRNPA2B1,SLC31A1,KDM2A,TNFAIP8,ATP2A2,PPP6C,INTS12,CRY2,ECD,FAM76B,CREB1,SMARCE1,RNF5,EIF5A,ELOVL5,RPRD1A,ERF,TBRG4,GSTCD,RAB1A,FOXRED1,ERC1,POLR2A,ARF4,SRSF1,EPB41,CBX3,MASTL,GNAS,NEK1,GOLGA2,STT3A,ZNF367,ATP6V0C,FAU,EHD4,PTOV1 |
| 3.240e-02 | -3.43 | lamellipodium organization | biological process | GO:0097581 | 40 | 11 | 17256 | 2622 |
WASF2,CYFIP1,ARPC5,SNX2,NCK1,RAC1,VAV2,ARFIP2,ABI1,CARMIL1,NUP85 |
| 3.240e-02 | -3.43 | histone ubiquitination | biological process | GO:0016574 | 40 | 11 | 17256 | 2622 |
PAF1,HUWE1,UBR2,SUZ12,PCGF6,CTR9,USP22,PCGF1,CDC73,DDB1,RYBP |
| 3.244e-02 | -3.43 | KH | smart domains | SM00322 | 37 | 10 | 9493 | 1367 |
MEX3C,KHSRP,FXR1,PCBP1,ANKHD1,PCBP2,PNO1,AKAP1,KRR1,FUBP1 |
| 3.249e-02 | -3.43 | cell proliferation | biological process | GO:0008283 | 680 | 121 | 17256 | 2622 |
TXN,CKLF,ARID2,RPS6KA1,RAF1,RAC1,TPX2,CUL1,BCL2L1,KIF2C,DUSP22,TCF19,MXD1,RPL23A,CDK5,RRN3,PA2G4,PCNA,KIF14,ETV6,MRPS27,TXLNA,PDS5B,ECD,PLCL2,NAA35,TACC3,DVL2,MRM2,PRPF19,PLK1,BAK1,ERCC1,MAPRE2,KLF10,KIF15,MKI67,PSMG1,FRAT2,AURKB,CADM1,AZI2,SOX4,GINS4,HHEX,CDC16,STAT6,STAT1,UHRF2,SCARB1,CLU,PDXK,H3F3A,SMAD1,MAPK1,NAA60,SMAD4,NUMB,USP13,POU3F2,MIF,MCM10,MAPRE1,PDAP1,DCTN2,CENPF,RRM1,BTN3A1,RACGAP1,ZNRF3,PPP3CB,CDK11B,CNOT11,PSEN1,SRRT,FZD6,YY1AP1,FGFR3,EIF2S2,PTEN,PPP1R8,PELO,ARHGEF1,PRDM4,CTPS1,AXIN2,ARHGEF2,BCL2,FBXL7,ORC3,CITED2,STAT3,GNAI2,NUDC,GINS1,TGFB1,NASP,KAT2A,CREG1,TACC1,PRKDC,ZMYND11,ASPM,APPL1,PICALM,PRDX1,XRCC5,PCM1,PALB2,CDC27,TFDP1,FAM83D,APPL2,IMPDH1,DNPH1,NDE1,BTBD10,CD81,HRAS,BYSL,IFI16 |
| 3.251e-02 | -3.43 | GSE28783_CTRL_ANTI_MIR_VS_UNTREATED_ATHEROSCLEROSIS_MACROPHAGE_UP | MSigDB lists | GSE28783_CTRL_ANTI_MIR_VS_UNTREATED_ATHEROSCLEROSIS_MACROPHAGE_UP | 187 | 38 | 17377 | 2626 |
ZNF207,CYLD,SRSF6,TAP1,FLOT1,ARFIP2,ASAH1,TWF2,EIF1B,ZNF518A,PDXDC1,BCAT2,RAD23A,RBM17,PTEN,EI24,JOSD1,NDUFS8,RBM3,APOOL,SMARCE1,CFL1,GPX4,MYBL2,ELP4,MCL1,NDUFA7,MEN1,ARPC1A,TWISTNB,TSC1,RAD51C,PPP2R5A,GOLGA8A,DCAF11,LPCAT4,TCOF1,H3F3A |
| 3.251e-02 | -3.43 | GSE3691_CONVENTIONAL_VS_PLASMACYTOID_DC_SPLEEN_UP | MSigDB lists | GSE3691_CONVENTIONAL_VS_PLASMACYTOID_DC_SPLEEN_UP | 187 | 38 | 17377 | 2626 |
FEZ2,MED13L,UBE2Q1,TOP2B,DAZAP2,CRLF3,FKBP1A,RNFT1,SRI,HADHB,UPF2,CLDND1,MARCH2,POU2AF1,BIRC3,CPOX,MFNG,WDR81,MPG,SOX4,NDRG3,MARK2,SMAP2,PLEKHF2,RAB18,VEZF1,ZNF777,HIPK2,ARAP1,SLC25A19,CANT1,PSAP,WIPI2,MAP3K5,GLCCI1,LONP2,HIPK3,TMEM131 |
| 3.251e-02 | -3.43 | GSE23505_UNTREATED_VS_4DAY_IL6_IL1_TGFB_TREATED_CD4_TCELL_DN | MSigDB lists | GSE23505_UNTREATED_VS_4DAY_IL6_IL1_TGFB_TREATED_CD4_TCELL_DN | 187 | 38 | 17377 | 2626 |
TCF12,ASH1L,CASP6,RAB11B,PHF23,SESTD1,MANBA,EZH1,IKBIP,ZNF518A,QSOX2,HMG20A,RNF19A,MAML1,CNOT6L,ARID4A,ABCC5,LDHB,ACP2,ACSL3,LACTB,SREK1,SOX4,TTC33,CYB5A,ANKZF1,WDR11,CERS6,ACOX1,HAGHL,GLG1,ACBD4,ACAT1,DMWD,SMAD4,RNF139,GPATCH4,DDX42 |
| 3.251e-02 | -3.43 | GSE33424_CD161_INT_VS_NEG_CD8_TCELL_DN | MSigDB lists | GSE33424_CD161_INT_VS_NEG_CD8_TCELL_DN | 187 | 38 | 17377 | 2626 |
MBD1,CMAS,ABCA3,UFC1,ANKH,SIKE1,IKBIP,DUSP22,POFUT1,FAM8A1,EEF2K,ADD3,INPP5A,SLC44A1,CNPY4,ANXA5,SLC38A10,CDC25B,MTPN,RHOA,ANKRD37,ATG9A,HELB,ANKRD33B,CUL3,WDR81,CADM1,PRMT2,PTTG1IP,ZNF862,DUSP3,SNAP29,COX7A2L,OAZ2,H2AFX,TFDP2,E2F2,ZMAT3 |
| 3.251e-02 | -3.43 | GSE39110_UNTREATED_VS_IL2_TREATED_CD8_TCELL_DAY3_POST_IMMUNIZATION_DN | MSigDB lists | GSE39110_UNTREATED_VS_IL2_TREATED_CD8_TCELL_DAY3_POST_IMMUNIZATION_DN | 187 | 38 | 17377 | 2626 |
TRIP12,FOXM1,POC1A,DAP,RAF1,SRGN,SMC6,HMGN3,RAB6A,FKBP2,BLM,PMVK,LCLAT1,NPLOC4,FBXO5,RPA2,SNRNP25,PCNA,CLIC4,INTS7,MYBL1,TIMP2,MAPRE2,RAD51AP1,CKAP2L,AMDHD2,EIF4H,CBFB,RPA1,NUCB1,KIF18A,KIF18B,POLE,H2AFX,NUP62,WDR62,EHD4,CD81 |
| 3.251e-02 | -3.43 | GSE25088_ROSIGLITAZONE_VS_IL4_AND_ROSIGLITAZONE_STIM_MACROPHAGE_DAY10_DN | MSigDB lists | GSE25088_ROSIGLITAZONE_VS_IL4_AND_ROSIGLITAZONE_STIM_MACROPHAGE_DAY10_DN | 187 | 38 | 17377 | 2626 |
GPR132,URB2,PPP1R15B,VTI1A,RRAGC,SECISBP2,CNTROB,XPNPEP3,C2orf49,MDM2,DNAAF2,RAB4A,MINPP1,ALDH18A1,LDLRAD3,ABCC1,SAP30,ANKRD37,AATF,IDH3A,PSPC1,NUP155,MEF2D,MPG,PHF6,AKAP1,ITPRIPL1,PPP2R5A,ETS2,WDR4,PML,RGL1,DMWD,ZSWIM3,BYSL,PFKP,FAM72A,CCDC137 |
| 3.251e-02 | -3.43 | GSE5589_LPS_VS_LPS_AND_IL10_STIM_MACROPHAGE_180MIN_DN | MSigDB lists | GSE5589_LPS_VS_LPS_AND_IL10_STIM_MACROPHAGE_180MIN_DN | 187 | 38 | 17377 | 2626 |
SLC12A7,TOMM20,TXN,SCOC,NOP2,KRBA1,SRSF6,STRN4,NKD2,NIPA2,ADPGK,ARF1,PCBP1,WRB,DAD1,NAA50,C8orf59,MYBL1,HNRNPM,TGFB1,ELOVL5,ERMP1,SEPT9,TSPYL4,DHX29,ATP6V0A1,CLNS1A,ECH1,SRSF1,RAD51C,TMEM41A,NAP1L1,IDE,HNRNPR,RBMX,NRM,MEGF9,RGL1 |
| 3.251e-02 | -3.43 | GSE26890_CXCR1_NEG_VS_POS_EFFECTOR_CD8_TCELL_DN | MSigDB lists | GSE26890_CXCR1_NEG_VS_POS_EFFECTOR_CD8_TCELL_DN | 187 | 38 | 17377 | 2626 |
KDM4A,GNPDA1,DAP,HNRNPUL2,HABP4,CHKB,MIEN1,VASP,MLX,ATIC,RRBP1,SEPT11,CDC25B,DNAL4,SPTAN1,RHOA,TK1,DHX29,ZNF512,PPP1R21,KIAA0930,PARP4,DNAJC9,WBP1,FAS,SEC31A,SLCO4A1,PDRG1,CHD3,SNAP29,NRM,HAGHL,H2AFX,SSNA1,CCNB2,LONP2,HIGD2A,CCDC137 |
| 3.251e-02 | -3.43 | GO_RNA_MODIFICATION | MSigDB lists | GO_RNA_MODIFICATION | 103 | 23 | 17377 | 2626 |
METTL1,CTU2,TRMT6,NSUN2,METTL2A,ALKBH5,GAR1,PARN,METTL3,GTPBP3,DUS3L,DUS4L,RBM47,METTL14,TRMU,TYW5,WDR4,UBA5,FTSJ1,OSGEPL1,FBL,NSUN4,FTSJ3 |
| 3.251e-02 | -3.43 | GO_EARLY_ENDOSOME_MEMBRANE | MSigDB lists | GO_EARLY_ENDOSOME_MEMBRANE | 103 | 23 | 17377 | 2626 |
SNX8,RAB14,SNX27,CLCN3,SNX2,HLA-E,RAC1,RUFY1,TMEM165,RAB5B,STAM,APPL1,HLA-A,PLEKHF2,PI4K2A,HLA-B,RAB21,HGS,MTMR4,PML,APPL2,PIKFYVE,EHD4 |
| 3.251e-02 | -3.43 | RNA degradation | KEGG pathways | hsa03018 | 77 | 19 | 7161 | 1149 |
EXOSC6,BTG2,LSM8,EXOSC9,PARN,PATL1,PABPC4,CNOT3,EDC3,CNOT9,EXOSC7,LSM6,EXOSC1,DCP1A,CNOT6,CNOT6L,PABPC1,TOB1,PFKP |
| 3.251e-02 | -3.43 | RNA degradation | KEGG pathways | ko03018 | 77 | 19 | 7161 | 1149 |
EXOSC6,BTG2,LSM8,EXOSC9,PARN,PATL1,PABPC4,CNOT3,EDC3,CNOT9,EXOSC7,LSM6,EXOSC1,DCP1A,CNOT6,CNOT6L,PABPC1,TOB1,PFKP |
| 3.252e-02 | -3.43 | Cul4-RING E3 ubiquitin ligase complex | cellular component | GO:0080008 | 36 | 10 | 18223 | 2701 |
DTL,DCAF6,RBX1,DCAF15,DCAF8,DDA1,DCAF11,CDKN1B,DCAF5,DDB1 |
| 3.252e-02 | -3.43 | regulation of centrosome cycle | biological process | GO:0046605 | 55 | 14 | 17256 | 2622 |
CHMP2A,PDCD6IP,KAT2A,CENPJ,POC1A,NUP62,XRCC3,CHMP4B,BRCA1,CCNF,CHMP2B,MCPH1,KIF11,GEN1 |
| 3.253e-02 | -3.43 | GO_POSITIVE_REGULATION_OF_PROTEIN_LOCALIZATION_TO_NUCLEUS | MSigDB lists | GO_POSITIVE_REGULATION_OF_PROTEIN_LOCALIZATION_TO_NUCLEUS | 125 | 27 | 17377 | 2626 |
DDX58,TGFB1,PLK1,CCT2,PPP3CA,TRIM8,RHOA,CHERP,KAT7,PPP3CB,BRCA1,NUTF2,MAPK14,PARK7,CCT8,TRIM28,KPNA1,PIK3R2,OGT,PPP3R1,GTSE1,STK11,ZNF268,MAVS,SMAD4,HNRNPM,CDKN2A |
| 3.253e-02 | -3.43 | PETROVA_ENDOTHELIUM_LYMPHATIC_VS_BLOOD_UP | MSigDB lists | PETROVA_ENDOTHELIUM_LYMPHATIC_VS_BLOOD_UP | 125 | 27 | 17377 | 2626 |
GINS1,RMND5A,PLK1,TK1,GMFG,PPP1R2,FOXM1,ACSL3,PTTG1,CENPF,MYBL2,KIF2C,AURKB,CCNB1,LYN,KIF11,SPAG5,CREM,CCNA2,ADD3,PDLIM1,HMGB2,ARRB2,CCNB2,UBE2C,SMC4,USP13 |
| 3.256e-02 | -3.42 | guanyl-nucleotide exchange factor complex | cellular component | GO:0032045 | 13 | 5 | 18223 | 2701 |
RAP1A,PDE3B,ELMO1,RIC1,WDR41 |
| 3.256e-02 | -3.42 | cytoplasmic ubiquitin ligase complex | cellular component | GO:0000153 | 13 | 5 | 18223 | 2701 |
SYVN1,RBX1,VHL,ATG3,SEL1L |
| 3.256e-02 | -3.42 | condensed chromosome outer kinetochore | cellular component | GO:0000940 | 13 | 5 | 18223 | 2701 |
PLK1,SKA3,CCNB1,SPDL1,CENPF |
| 3.256e-02 | -3.42 | DNA-directed RNA polymerase I complex | cellular component | GO:0005736 | 13 | 5 | 18223 | 2701 |
POLR1B,POLR2L,ZNRD1,POLR2K,TWISTNB |
| 3.256e-02 | -3.42 | telomere cap complex | cellular component | GO:0000782 | 13 | 5 | 18223 | 2701 |
TERF2IP,POT1,TERF1,TERF2,XRCC5 |
| 3.256e-02 | -3.42 | nuclear telomere cap complex | cellular component | GO:0000783 | 13 | 5 | 18223 | 2701 |
TERF2IP,POT1,TERF1,TERF2,XRCC5 |
| 3.257e-02 | -3.42 | death-inducing signaling complex | cellular component | GO:0031264 | 9 | 4 | 18223 | 2701 |
FAF1,FADD,CFLAR,FAS |
| 3.257e-02 | -3.42 | post-mRNA release spliceosomal complex | cellular component | GO:0071014 | 9 | 4 | 18223 | 2701 |
LIME1,XAB2,DHX15,CRNKL1 |
| 3.257e-02 | -3.42 | female pronucleus | cellular component | GO:0001939 | 9 | 4 | 18223 | 2701 |
TET3,CCNA2,AKAP8,SLC2A1 |
| 3.257e-02 | -3.42 | DNA recombinase mediator complex | cellular component | GO:0033061 | 9 | 4 | 18223 | 2701 |
XRCC3,RAD51C,RAD51D,XRCC2 |
| 3.257e-02 | -3.42 | GDAP1 (ganglioside induced differentiation associated protein 1) | protein interactions | 54332 | 12 | 5 | 17029 | 2761 |
PSAP,MINPP1,EYA2,SUZ12,TUBB |
| 3.257e-02 | -3.42 | MSMO1 (methylsterol monooxygenase 1) | protein interactions | 6307 | 12 | 5 | 17029 | 2761 |
ATXN1,IMMT,VKORC1,EIF3A,DDRGK1 |
| 3.257e-02 | -3.42 | FAM184A (family with sequence similarity 184 member A) | protein interactions | 79632 | 12 | 5 | 17029 | 2761 |
BRAP,USO1,BRCA1,GOLGA2,APP |
| 3.257e-02 | -3.42 | Rab11fip1 (RAB11 family interacting protein 1 (class I)) | protein interactions | 75767 | 12 | 5 | 17029 | 2761 |
NUP62,ZKSCAN1,RAB11B,LYN,NARF |
| 3.257e-02 | -3.42 | PLBD2 (phospholipase B domain containing 2) | protein interactions | 196463 | 12 | 5 | 17029 | 2761 |
WDHD1,MRPL9,TFG,ECPAS,STRAP |
| 3.257e-02 | -3.42 | TMEM129 (transmembrane protein 129) | protein interactions | 92305 | 12 | 5 | 17029 | 2761 |
UBE2D3,DERL1,SYVN1,HLA-A,SEL1L |
| 3.257e-02 | -3.42 | UTP11 (UTP11, small subunit processome component) | protein interactions | 51118 | 12 | 5 | 17029 | 2761 |
THNSL1,RRP15,APP,IFI16,MRPL34 |
| 3.257e-02 | -3.42 | Pds5a (PDS5 cohesin associated factor A) | protein interactions | 71521 | 12 | 5 | 17029 | 2761 |
EIF5A,ANXA5,PTMS,FUS,NACA |
| 3.257e-02 | -3.42 | Sqstm1 (sequestosome 1) | protein interactions | 18412 | 12 | 5 | 17029 | 2761 |
CEP63,SMAD2,SMURF1,SMAD4,DNAJB2 |
| 3.257e-02 | -3.42 | WFDC2 (WAP four-disulfide core domain 2) | protein interactions | 10406 | 12 | 5 | 17029 | 2761 |
PTPRF,WDR81,WDR91,BTBD1,LMNA |
| 3.257e-02 | -3.42 | THAP4 (THAP domain containing 4) | protein interactions | 51078 | 12 | 5 | 17029 | 2761 |
MOB4,ACTB,GFER,APP,MAPK6 |
| 3.257e-02 | -3.42 | PPP1R11 (protein phosphatase 1 regulatory inhibitor subunit 11) | protein interactions | 6992 | 12 | 5 | 17029 | 2761 |
UBXN2A,PPP1R2,UBXN2B,DUT,PPA2 |
| 3.257e-02 | -3.42 | ADCK5 (aarF domain containing kinase 5) | protein interactions | 203054 | 12 | 5 | 17029 | 2761 |
CHCHD2,ADCK5,IMMT,FUS,STOML2 |
| 3.257e-02 | -3.42 | GTF2A2 (general transcription factor IIA subunit 2) | protein interactions | 2958 | 12 | 5 | 17029 | 2761 |
TERF1,POLR2A,TERF2,PTPN11,TBPL1 |
| 3.257e-02 | -3.42 | Akap8 (A kinase (PRKA) anchor protein 8) | protein interactions | 56399 | 12 | 5 | 17029 | 2761 |
PKP4,SEC16A,HNRNPH3,MATR3,HNRNPM |
| 3.257e-02 | -3.42 | VAMP1 (vesicle associated membrane protein 1) | protein interactions | 6843 | 12 | 5 | 17029 | 2761 |
SNAP29,SNAP23,BCAP31,LMNA,CDKN2A |
| 3.257e-02 | -3.42 | FOXI1 (forkhead box I1) | protein interactions | 2299 | 12 | 5 | 17029 | 2761 |
SMPD4,COPS6,TOMM40,DDX39A,APP |
| 3.257e-02 | -3.42 | HIST1H2AM (histone cluster 1 H2A family member m) | protein interactions | 8336 | 12 | 5 | 17029 | 2761 |
CUL1,PCGF1,MCM2,CAND1,ILF3 |
| 3.257e-02 | -3.42 | PTER (phosphotriesterase related) | protein interactions | 9317 | 12 | 5 | 17029 | 2761 |
S1PR2,MCM2,MRM3,PRKDC,XRCC5 |
| 3.257e-02 | -3.42 | NSMCE3 (NSE3 homolog, SMC5-SMC6 complex component) | protein interactions | 56160 | 12 | 5 | 17029 | 2761 |
SMC6,NSMCE4A,TRIM28,NSMCE2,E2F1 |
| 3.257e-02 | -3.42 | ZNF202 (zinc finger protein 202) | protein interactions | 7753 | 12 | 5 | 17029 | 2761 |
TK1,ZNF473,SNX2,RCOR3,ZMYM3 |
| 3.257e-02 | -3.42 | AMZ1 (archaelysin family metallopeptidase 1) | protein interactions | 155185 | 12 | 5 | 17029 | 2761 |
WASF2,CYFIP1,NCKAP1,CYFIP2,ABI1 |
| 3.257e-02 | -3.42 | SDHAF3 (succinate dehydrogenase complex assembly factor 3) | protein interactions | 57001 | 12 | 5 | 17029 | 2761 |
SDHB,BOLA3,ATP5PF,SDHA,ECH1 |
| 3.257e-02 | -3.42 | TM4SF20 (transmembrane 4 L six family member 20) | protein interactions | 79853 | 12 | 5 | 17029 | 2761 |
CAB39,RHOA,LMNA,HSDL1,EBP |
| 3.257e-02 | -3.42 | FBXL6 (F-box and leucine rich repeat protein 6) | protein interactions | 26233 | 12 | 5 | 17029 | 2761 |
MPHOSPH8,TFG,PTEN,ETV6,KBTBD7 |
| 3.260e-02 | -3.42 | cellular response to chemical stimulus | biological process | GO:0070887 | 2786 | 456 | 17256 | 2622 |
RAB14,TXN,MAX,H2AFZ,ADD1,CXXC1,CUL1,CCNB1,PARK7,EEF2K,CDK5,USF1,PSMD1,DNM2,TRA2B,MOB1A,TIPARP,DNMT1,CDC5L,PLK3,BAK1,KLF10,GABPA,AKT2,GNG7,HNRNPF,MCL1,MCM2,SLC25A5,SMAD2,WAS,RPS27A,PSMD8,PRDX5,PTPN7,ITGB1,MPV17,ATP6V0C,RNASEL,SMAD1,ARRB2,HDAC2,PFKP,PDCD4,SLC25A33,DDX58,HSPH1,SEC61G,POLR2K,HLA-E,PRKAA1,DHX9,PXMP2,CYCS,ITGB5,PSEN1,PSMD9,METTL3,CDC73,LMNA,CFLAR,TFAP4,FKBP1A,SLC31A1,RNF121,PDXP,MEGF8,EFTUD2,DAPK1,ATP6V0A2,MYDGF,GNAI2,NUP85,SOCS5,CYFIP1,ETV3,ERO1A,MYBL2,USP10,BCLAF1,SRSF5,ADRB2,ARID1A,PKM,ELK1,KDM3A,MTR,RHOB,PSMB3,TWISTNB,FAS,XRCC5,DERL1,SEC31A,CAT,EPRS,FNTA,POLR2J,CSK,RBMX,PIAS2,SMPD4,MAP3K5,YY1,CDK2,RNF14,EGLN1,RHOG,KARS,ATXN3,DNMT3A,RWDD1,CKLF,NQO1,RAB11B,UBR2,RAF1,RAC1,ACTR3,ANK3,WDTC1,BCL2L1,PRKACA,CPNE3,APP,GNB2,CRKL,CCNA2,ATP2A2,SHC1,SP100,RALB,MTMR4,ADCY9,SOCS6,CDKN1B,MAVS,TALDO1,CFL1,DCTN1,ATP6V1G1,ADCY7,GPX4,CPNE1,SHOC2,SEC61B,POLR2L,WBP2,POLR2D,CUL3,ATP6V0A1,DNAJA1,SHCBP1,PSMB9,SERP1,MAT2A,DDX17,SOCS7,ANKZF1,ALDH3B1,HSPA4,SEC61A1,JAK1,VPS26B,DGCR8,GUCY1B1,SAFB,HIPK2,STAT1,ATF6,TICAM1,FUS,PPP5C,XRCC4,LRP8,DYNC1LI2,CSNK1D,LRCH1,ADAM23,POU3F2,SLC41A1,TWNK,FLOT1,MYNN,AKT1S1,SDF2L1,IP6K2,BLM,ETS1,IL21R,FOXO3,HLA-A,TUT4,PIP5K1C,SRXN1,GTF2F1,CAPN2,PSMD2,PDCD10,CLIC4,SUV39H2,PTEN,FUT8,PTPN11,CNN2,CARF,CITED2,CREB1,MAP3K14,UBE2M,NCOA2,HNRNPM,PDPK1,STAU1,PPP3CA,TNFAIP3,KAT2A,NET1,DENND4C,RPL8,TBRG4,KCNQ1,PDE3B,POLR2A,PRDX1,YIF1A,SELENOW,KIF18A,KEAP1,LTBP4,PRDX3,TATDN2,WNT5B,MAPK6,PML,KHSRP,HMGB2,DDX5,ASNA1,PSAP,USF2,YWHAH,CPEB2,FAM83G,SRM,RORB,AGRN,PTP4A3,SLC29A1,SIRT2,MAPK14,BECN1,BIRC2,BCAT2,SSR1,PRNP,ABL2,RAB8A,PCNA,RAP1A,CDC42,EIF4A3,RAB35,IL6ST,PIK3R2,TXLNA,AKR1B1,ZFYVE27,OGG1,CARM1,PTPRK,LARS,PTPN18,TRIM8,RBX1,VHL,EZR,UBE2V1,CDC6,IL12RB1,BRCA1,SOX4,PRKRA,MPC1,OPTN,DPYSL3,PAF1,BRWD1,SOCS4,PQBP1,ADAM9,ACTB,CHEK2,ATP6V0E1,C2CD5,PSMC1,UBE2D3,PPP1R12A,PHB2,AGTRAP,CIB1,CDIP1,LAMTOR3,TIA1,MEF2A,THRAP3,PPP3CB,EPHX2,ARID1B,SRRT,RHBDD1,RB1,NUS1,TIGAR,MBD2,CAPZA1,CTR9,TIMELESS,BCL2,ATP6V0D1,PREB,HP1BP3,ABCC1,ABHD2,POLR2I,AACS,NQO2,OXR1,GBA,PSMA1,KRAS,SYVN1,APPL1,DAPK3,ISG15,IRF5,PSMC4,RXRB,TSC1,SYNCRIP,NSMF,KLHL15,NFIL3,LAMTOR4,SLC16A1,PITPNA,NUP62,YWHAZ,RUVBL2,SNRNP70,EHD4,HNRNPDL,TOB1,ADNP2,SMARCD1,GNPNAT1,SMARCA4,RRAGC,IRF3,ATP6V1B2,DUSP22,TWF2,LYN,HNRNPA2B1,VAV1,ATP6V0B,PDK2,UBXN2A,PSMA6,MDM2,AKAP8,CORO1A,AHCYL1,PDIA6,CTDSP2,SPIDR,HTRA2,PPIF,KDM3B,BIRC3,POLR2G,CGAS,PSMA8,SELPLG,SLC26A6,PSMB7,ERBIN,EDEM2,TOLLIP,ATP1A1,IDE,TAB2,PSMD3,STAT6,ARNTL,SCARB1,NCOA1,SMURF1,MAPK1,ABCA1,SMAD4,PARD3,MIF,GCLM,CASP6,RAE1,AGO2,ARID5A,ARF1,AP3S1,DNAJB9,TFRC,PTPN2,KIF5B,GSTK1,FGFR3,IRF4,CTSS,GRK2,TANK,ARHGEF2,PTGES3,STAT3,CAMK2G,MYO5A,RNF5,TXNL1,TGFB1,PAQR6,PPP1R9B,RHOA,ADAM17,PRKDC,PRKAR1B,RANGAP1,MEN1,HSPA1B,MAPK3,CNOT9,CTSL,HLA-B,CACNB1,TRIM26,ATP6V1D,UPF1,PLAA,BIRC5,TWSG1,ZC3H7B,E2F1,PKD2,RBPJ,SRSF3,PLOD3,ATP6V1C1,NR2F2 |
| 3.267e-02 | -3.42 | FAN1 (FANCD2 and FANCI associated nuclease 1) | protein interactions | 22909 | 47 | 13 | 17029 | 2761 |
ANKLE2,SUB1,PCNA,HSPBP1,RFC3,RBM34,MIER1,PMS2,YWHAZ,BLM,HEXA,FANCI,PRPF4B |
| 3.267e-02 | -3.42 | POGZ (pogo transposable element derived with ZNF domain) | protein interactions | 23126 | 47 | 13 | 17029 | 2761 |
ZNF428,NRF1,HGS,SUMO2,VAV2,NFATC2,CREB1,HDGFL2,DAZAP2,APP,MAD2L2,CBX3,ZBTB24 |
| 3.267e-02 | -3.42 | EIF4EBP1 (eukaryotic translation initiation factor 4E binding protein 1) | protein interactions | 1978 | 47 | 13 | 17029 | 2761 |
PPP2CA,CHMP2A,HNRNPAB,GGA1,AKT2,PRKDC,AGO2,YJU2,CSNK2A1,MAPK14,MAPK1,RHEBL1,MLST8 |
| 3.267e-02 | -3.42 | UPF3B (UPF3B, regulator of nonsense mediated mRNA decay) | protein interactions | 65109 | 47 | 13 | 17029 | 2761 |
UTP20,SART1,STAU1,UPF1,SEC61A1,EIF4A3,RBM8A,RNPS1,UPF2,USP21,RLIM,SRPK2,CAND1 |
| 3.267e-02 | -3.42 | FAM234B (family with sequence similarity 234 member B) | protein interactions | 57613 | 47 | 13 | 17029 | 2761 |
DEPDC1,B4GALT5,TMX4,SLC25A51,PDS5B,TBRG4,TNPO2,B4GALT1,ADPGK,UBE3C,SPDL1,CCNB2,SPAG5 |
| 3.267e-02 | -3.42 | EEF2K (eukaryotic elongation factor 2 kinase) | protein interactions | 29904 | 47 | 13 | 17029 | 2761 |
PA2G4,TP53RK,DUS3L,EIF4A3,MAPKAPK3,RPS6KA1,RAE1,PRKAA1,PRKAR1B,RANGAP1,UBE3C,MAPK14,PRKACA |
| 3.267e-02 | -3.42 | PLOD2 (procollagen-lysine,2-oxoglutarate 5-dioxygenase 2) | protein interactions | 5352 | 47 | 13 | 17029 | 2761 |
CSDE1,HSPH1,GART,UGP2,VHL,TPP2,AP2B1,NUSAP1,RUVBL2,XPO7,TERF1,FAF1,TERF2 |
| 3.267e-02 | -3.42 | KOKKINAKIS_METHIONINE_DEPRIVATION_96HR_UP | MSigDB lists | KOKKINAKIS_METHIONINE_DEPRIVATION_96HR_UP | 114 | 25 | 17377 | 2626 |
ERCC1,TIMP2,CASP6,BTG2,DCTD,BRCA1,MTR,RHOB,FAS,CFLAR,MAT2B,SHC1,PTEN,IL6ST,DUT,TANK,RAD23B,DAPK1,CDKN1B,RNASEL,CDC25B,SMAD1,SMAD4,SPTAN1,FDFT1 |
| 3.273e-02 | -3.42 | lung-carcinoma-small_cell_carcinoma | COSMIC cancer mutations | lung-carcinoma-small_cell_carcinoma | 10147 | 1553 | 17385 | 2587 |
ZBTB10,TSC2,ABCC10,LACTB2,CCNL2,RBM4,ZNF275,FBXO22,EEF2K,CDKN2C,USF1,RAD23B,ATP13A3,AP1M1,DNM2,UPRT,CRY2,RNF26,TIPARP,MGAT5,USP34,BAK1,CCDC57,ERCC1,ZNF559,RHOBTB3,NRAS,GABPA,EHMT1,KIF15,HNRNPF,WDHD1,MIER2,DIDO1,MCM2,RAB22A,ARF4,KRIT1,AHNAK,SMAD2,MID1IP1,RAD18,OGT,RNASEL,SMAD1,SMNDC1,PDCD4,SLC25A33,NXT2,HIVEP3,CLSPN,KIAA0100,SEC61G,RHOC,MUM1,TRIO,DHX9,RAB23,EIF2AK4,PDCD7,APH1B,CDC73,ATG4A,TMEM179B,TFAP4,ERV3-1,PDXP,C4orf3,RNFT1,RIMS3,MEGF8,FBXO7,EFTUD2,GEMIN4,MRPL21,MVP,NUP85,PABPC1,PHKG2,LUC7L2,SRSF11,AGGF1,FOXK1,RBM42,GTPBP4,ITM2A,USP10,BCLAF1,ELK1,EIF4H,MAGED2,KPNA1,TXNDC16,ETS2,WIPI2,MRPL3,ALS2,EXOC3,RHOG,KARS,TRIM41,PTTG1,ANK3,C5orf30,TPX2,LCLAT1,RCOR3,REPS1,RBM23,FBXL6,ZNF420,AHCTF1,MTA1,UBA5,GMEB1,NSFL1C,CLCN6,INTS12,ZC3H3,RPRD1B,ARL5A,CGGBP1,SNX8,ERMP1,GOPC,IDH3A,CRNKL1,CIRBP,E2F3,PFKFB3,GORAB,MEF2D,TANC1,RAB1A,GIGYF1,TMEM184C,KIF2A,PPP2CA,LSM6,CORO1C,NSMCE2,CAMKMT,RNF38,CENPBD1,PPP5C,USP13,ZNF445,SRSF6,CCM2,FLOT1,BTN3A1,ATG2B,IP6K2,WDR5,PMVK,IFT27,SLC25A43,NEIL2,PPP1R3B,RPA2,PSMD2,PDCD10,CLIC4,ITGB8,HUWE1,ARF5,ARHGEF1,ANXA5,LTN1,UBE3B,NAP1L4,ST8SIA2,FBXL19,GTF2H2,SPTAN1,STAU1,DDX24,TACC1,MRS2,LDHA,HEBP2,RAB3IP,PICALM,UTP20,MAGT1,FAM3C,DBI,AEN,CD81,PARP10,YWHAH,TMEM131,WDR13,TRIM11,FAM129A,SNX15,RUFY1,TRIM65,FANCI,PAPOLA,ZER1,PRNP,FANCL,RAB8A,NUP210,NT5DC1,INTS1,IL6ST,SLC44A1,MTPN,ASB6,TACC3,VPS13B,PLK1,PTPN18,SEPT9,CELSR2,RBX1,APH1A,SNRPB,RAD51AP1,CKAP2L,CDC6,UBE2V1,UTP3,PBRM1,USP21,TRIM4,FBXO28,CHD3,E2F4,BCL7C,ADAM9,KPNA2,DVL1,CLN3,FAM208A,NGLY1,POT1,NUMB,CCDC137,FUBP1,RMND5A,PARP12,HJURP,FAM53C,DNAJB2,CENPF,NKD2,LAMTOR3,COX4I1,ADCK5,CDK13,RAB6A,DNAJB1,NCKAP1,ARID1B,TNS3,C1GALT1,CCP110,KIF13B,MBD2,ZNF746,XPA,ARL6IP1,CTR9,RBM3,GLE1,LRSAM1,HDHD2,ABHD2,DCAF8,NSDHL,ACSL3,LDB1,CAMSAP1,MAP4K3,METTL22,ICAM2,ARMC8,STYXL1,IRF5,NMT2,HAUS8,RXRB,SDHB,MBIP,PCM1,GALNT2,TMEM168,ORMDL2,COX7A2L,NLRC5,ZDHHC7,SIL1,RUVBL2,BTBD10,MYO9A,CCNB2,UNC13C,USP7,SART1,TRAF7,ARID2,TMX4,TOR1AIP1,LAGE3,ATP6V1B2,PCBP1,LYN,BCAP31,VAV1,MRPL50,NRF1,PSMA6,ZNF473,BRPF3,WDR44,PIN1,TARDBP,CABLES2,TOP1MT,STRAP,SPSB3,PRPF19,SNX25,KDM3B,ARHGAP17,CLCN3,BIRC3,RAB7A,NUP155,DCLRE1C,CHMP2B,EIF3H,RHBDF2,IDE,DHX16,RBL1,STK38,UBXN2B,FASTK,UHRF2,AP1S1,XRCC3,H3F3A,SLC22A23,SMAD4,RAD51D,PARD3,BCL2L12,SLC30A9,NADSYN1,MCM10,KLHL21,HMGN3,ARF1,NCAPG,SCYL2,TUBGCP2,DNAJB9,FZD6,HERC3,HOMER1,CTSS,POLR1B,ORC3,RNF5,RNLS,PPAN,RHOA,HMGN5,BTAF1,ABCF2,TUFM,TOP3A,ARHGEF12,PCGF1,ZFR,DDX23,RAB18,TRIM26,PDCD6,ATP6V1D,L3MBTL3,FAM110A,NEIL3,BBX,E2F1,USP20,IMPDH1,RBPJ,NR2F2,PGAM1,HIPK3,NUP188,MAX,PNISR,PDCD6IP,GXYLT1,LUZP1,PRKCSH,ADAM10,TSC22D3,CXXC1,AP3M2,USP39,CUL1,GYG1,UBE2I,PARK7,MYEF2,SLC25A37,ASPHD2,ANKRD26,PA2G4,NOL11,RAB4A,SUCLG2,SMARCE1,CDC5L,SRP72,OSBP2,KLF10,NSUN2,LACTB,USP22,RFC2,CBFB,RAB2B,EIF3A,ZMYM3,IWS1,DOT1L,MAP3K4,ANKRD10,HHEX,WAS,KIF18B,TPP2,LUC7L3,C1orf109,BTF3,PTPDC1,ZMAT3,NMD3,B4GALT2,PTOV1,PRPF38B,RECQL,C9orf78,COX5B,DNAJC5,EWSR1,GSPT2,PRKAA1,VAV2,ANKH,RRM1,DLGAP4,B4GALT1,CYCS,PRPF39,SUPT7L,PSEN1,ZNF79,CNOT3,YY1AP1,SPAG5,C12orf10,FAM192A,RPN1,CEP104,LHX8,KLHL5,ZNRF2,LRRC8D,PPP4R1,MSH2,DAPK1,FBXL7,CYC1,FAM171A1,SYTL3,APOL1,FDFT1,SOCS5,GCC2,PIGT,PRIM2,ELL2,EMB,RDH10,ZNF574,MFNG,C1orf35,GORASP2,ARID1A,ADRB2,MAP2K2,CCT8,MTR,TWISTNB,PHF6,AKAP1,PI4K2A,HMGN2,XRCC5,DERL1,CAT,PFDN5,SLCO4A1,TTC13,GOLGA2,RBMX,MED15,PIAS2,FAM83D,USP32,ARAP1,CEBPG,CABIN1,SMPD4,GPI,CDKN2A,CYTIP,TP53RK,ATXN3,REPS2,RAB11B,RAF1,KIAA0232,BCL2L1,EPM2A,NUDT19,DECR1,CCNA2,SIAH1,RALB,MTMR4,LPIN2,ADCY9,SOCS6,MRPS27,TTC3,TP53BP2,RNASEH2A,AQR,ILKAP,CDK12,SAP30,ANKLE2,BRD4,CDC123,DRAP1,NARF,LRRC8A,ELP4,PKMYT1,ASB13,ERC1,EML4,TRIM28,SUPT16H,RAD51C,CHMP4A,HINT1,DDOST,DGCR8,SAFB,LMBR1,FTSJ1,RWDD4,NCLN,BEND3,XRCC4,EYA2,DYNC1LI2,ADAM23,PRPF4B,NDUFS1,DEPDC1,SLC41A1,MECP2,MANBA,TKT,CBLL1,SECISBP2,POFUT1,HMG20A,HEATR5B,WWP2,JAKMIP1,EBP,RFWD3,AXIN2,PTPN11,MRPL54,MSH6,JMJD4,KAT2A,LONRF3,TMEM126B,RFXANK,RABIF,ADSL,FBXO9,PACS1,BMS1,KCNQ1,ARSK,KIF11,KLF6,MACF1,FADD,MYO1F,CBX3,INF2,ZHX1,PPP1R11,DDX5,DUSP11,WDR62,WDR91,TAF6,ESPL1,DDB1,DEF6,GPR89B,IPO4,FAM83G,POLA2,RORB,PIGM,ZNF76,MTX3,COPA,PTP4A3,UBE2Q1,ABCB10,MRPL19,SF3B2,DST,CDC42,RAB35,JAZF1,GPATCH1,TCEA1,SLC35C2,SRPK2,WDR41,LARS,DEAF1,SNRNP200,CCDC138,NCK1,LAP3,VHL,LRBA,PITPNB,KMT2C,PRPSAP1,ASF1B,MAN2A2,BRWD1,PPM1G,SH3GLB2,MIA2,ACBD4,CAB39,BAZ1B,STK11,CHEK2,CLU,ZSWIM3,MRPL13,CHPT1,DCAF5,UBE2D3,PPP1R2,PPP1R12A,ZCCHC8,NACA,UBXN1,PCSK7,THRAP3,RGS2,PRPF18,NUP205,ZRANB1,MCPH1,SLC12A2,CSNK1G3,TRAFD1,GBA,SYVN1,VKORC1,SLTM,DAPK3,ARHGAP15,EVC2,MASTL,UAP1,KLHL15,NFIL3,SIAH2,FN3KRP,SLC16A1,YWHAZ,EHD4,TOB1,TSEN15,N4BP2L2,ADNP2,TCF12,SNX27,PRKAB1,CORO7,MDH2,PMS2,SMARCA4,ORC1,CLCC1,EXT2,MXD1,USP5,IARS,KIF14,PPP6C,CS,CLTB,DNAL4,EBAG9,CSTF1,POU2AF1,RNF25,METTL2A,PCGF6,ATXN1,GLO1,OGDH,BICD2,TOLLIP,FANCE,PDHX,DUS3L,HNRNPR,HPS5,STAT6,ANP32E,FKBP5,CCDC125,BRD9,MAPK1,ABCA1,TMEM33,DNAJC2,TRIP12,SHPRH,RAE1,SCYL1,NUP54,VPS45,CHIC2,PAWR,MXD4,MYO9B,DCUN1D4,PIP4K2A,GFM2,XPR1,KIF5B,FASTKD3,FGFR3,PPIG,RRBP1,H2AFY,ARHGEF2,ATG13,LDLRAD3,ERI3,STAT3,FRMD8,AMPD2,TGFB1,B3GALT6,DCAF6,FAM49B,PSPC1,HELB,MIER1,ATP2C1,SCFD2,RFFL,COG1,RCOR1,NDRG3,TFEB,MTMR3,UPF1,ELMO1,ZC3H7B,DTX4,CENPT,ZMIZ1,PLOD3,TERF1,HRAS,RAB3IL1,RAB14,FGFR1OP,ADD1,MRPS15,KDM4A,PIGQ,XIAP,AGPAT1,DHX8,GLUD1,CNTROB,PPP1R16B,MIS12,PABPC4,CDK5,PSMD1,NEK6,RABGAP1L,SRSF4,PDS5B,NUP153,SENP1,PCBP2,MLST8,PLK3,PLEKHM3,TOPORS,MCL1,SMC2,PPFIA3,ICMT,TRIM47,PWWP2B,WDR11,AXIN1,LIMK1,ZNF689,ATE1,FBXL3,TFDP2,E2F2,PFKP,DDX42,SSRP1,CERK,TOP2B,SLC4A2,EZH1,ZNRF3,ITGB5,LMNA,MCTS1,RAVER2,DDX56,SLC38A5,INPP5A,INTS7,MCM5,PHF14,ZNF326,FOXN2,ETV3,RB1CC1,TSPYL4,C16orf72,PRRC2A,ZMYND11,DHX29,MAN1B1,TEX10,MYBL2,UHRF1BP1,SRSF5,MPG,MATR3,RHOB,LRRC14B,PTPRF,DTWD1,OSBPL11,DUSP3,SLAIN1,MDH1,CNOT6,NDE1,HEXA,RNF139,SNX14,EGLN1,ZNF207,ZNF296,ABCA3,TRERF1,UBR2,CHD1L,WDTC1,TMEM97,MYH9,NUF2,NIPA2,PRKACA,TCF19,APP,ANKIB1,KTN1,RAB21,PRKD3,SP100,UTP18,DUT,ZCCHC2,NUP107,ANKRD13C,ANAPC7,RNF19A,CEP63,RBM15,ATF2,GCC1,ADCY7,SHOC2,MAP4K4,RNPS1,ATP6V0A1,DNAJA1,TAZ,FKBP3,DDX17,GPR137,TAF2,CDC16,HIPK2,WDR7,CBLN2,MBOAT1,TICAM1,FUS,PDXK,ZBTB11,GEN1,LRP8,LRCH1,GALK1,SESTD1,SIKE1,GMCL1,JMJD6,UBE4A,ETS1,IL21R,ZNF92,KRI1,FBXO3,CAPN2,ERH,SUV39H2,NDUFB4,PPP1R8,GEMIN6,TPCN1,IMPA2,HNRNPM,LDHB,PDPK1,PPP3CA,TK1,TNFAIP3,POLK,GALC,ZNF512,MTMR12,PDE3B,DDX39A,RPA1,ZNF180,KIF18A,KEAP1,POLE,CCDC6,WNT5B,TATDN2,PITX1,MAPK6,CAPN7,LRPPRC,PML,LY75,HMGB2,RGL1,PSAP,WDR76,IGBP1,ANAPC4,FAF1,SNAPIN,COX15,DDX47,AGRN,THOC1,PPP1R15B,MCCC1,CSNK2A1,EBNA1BP2,S1PR2,SEC16A,GIT2,BIRC2,SSR1,LIN9,ABL2,PCNA,ZNF639,PIK3R2,ETV6,XRCC2,MYBL1,MRPL32,CCAR1,CDC37,PTPRK,SP3,BAZ2A,TLK1,GMFB,LNX2,LRP5,BRCA1,ANLN,PRKRA,STX16,RAB5B,RHEB,OPTN,TONSL,NRM,SOCS4,QRSL1,ACTB,GLCCI1,NUDT11,GEMIN7,RACGAP1,PPP3CB,DOCK11,RLF,CRLF3,RAPGEF6,LRRC14,RB1,NUS1,VASP,MED8,VMP1,PPIL2,SLC27A4,AFF1,AHDC1,MAML1,TMEM8A,ABCC1,PREB,CYTH1,TRAPPC9,AACS,RTF1,EIF2AK1,KRAS,UBE4B,ARPC1A,ZNF174,GOLGA4,PALB2,SYNCRIP,CDC27,PRPS2,PRMT7,NIPA1,CYLD,FOXM1,XAB2,SUMO2,DUSP22,COMMD8,RPL11,RAD23A,CSDE1,PDK2,MDM2,STRBP,PDCD2,CORO1A,MINPP1,METTL9,SAP30L,DVL2,POC5,PSMA8,BTG2,CYP20A1,SLC26A6,DNAJC9,MTMR6,NFATC2,PRPF3,ARL5B,RPSA,USP36,SRSF1,MRPL2,DNAJC10,ATP1A1,PLEKHG4B,CLK3,ZNF700,PSMD3,MAFK,CEP55,DNAJC17,NCOA1,LTA4H,USP53,SLC25A39,ZC3HC1,ZNF146,ATXN7L2,INTS2,CTDP1,GOLIM4,SMAP1,RRP15,GNE,CDT1,ARID5A,SMC6,NKRF,CSNK1A1,TFRC,PTPN2,IRF4,ABCD1,SS18L1,DDX31,CAMK2G,RPAP3,CNTN5,MLEC,SNX2,ZNF202,PPWD1,FAM50B,CHCHD6,NEU1,KPNA4,FBXO41,BIRC5,TFE3,GLG1,PGRMC1,FAM126A,RPS6KC1,UBE2C,ZNF496,PPCS,NDUFB6,TMEM41B,ZDHHC8,PLXNA1,CCNB1,IKBIP,SLC20A1,ASAP2,CDC25B,TFG,PLCL2,DNMT1,SEH1L,ORAI2,AKT2,PBK,NOL8,GNG7,MKI67,DDX20,AMDHD2,AURKB,GALNT7,SLC17A5,CCNF,SLC25A5,ZFAND5,RBM47,STT3A,PTER,WDR4,EIF2D,ITGB1,PTPN7,RRS1,TRAF5,ARRB2,ZNF598,HDAC2,DDX58,WSB2,PPIB,MUT,CHTF18,KIF23,NOTCH2,MAN2B1,METTL3,JMY,CFLAR,NDUFS4,FKBP1A,RNF121,MEX3C,SNX18,HDAC7,ATIC,CTPS1,PCYT2,PIKFYVE,RNF135,GNAI2,ANKHD1,EEF1D,TERF2,MORC3,PHF10,DDX28,ZNF84,SIGMAR1,PIP4K2C,KCTD20,DCTD,PLEC,RIT1,KDM3A,FAS,ADSS,EPRS,ZNF777,TMEM54,ZFP92,QARS,ERGIC3,ACLY,PPP3R1,LPCAT4,VCPIP1,YY1,PPP6R3,PPP6R2,MAP3K5,RNF14,CDK2,CABLES1,NRBP1,ZC3HAV1,DNMT3A,TRIP10,ZBTB37,URB2,SUZ12,RPS6KA1,SF3B1,MAGED1,RAC1,OLA1,ADPGK,AP1B1,SDHA,GNB2,PHC2,FLAD1,CRKL,TERF2IP,APLP2,ZNF75D,SHC1,KDM2A,UCHL5,TNPO2,CDKN1B,CCT2,MAPRE2,RFC3,ATP13A1,MKLN1,HMGN4,ERF,CUL3,KIAA1586,GALK2,CDC23,GAR1,POLG2,DHX57,HSPA4,JAK1,PPP2R5A,MRPL55,ACYP1,TBL3,H2AFX,SEL1L,STAT1,KLHDC4,TRIM32,B4GALT3,PDCD11,RHEBL1,POLQ,OTUD5,NCOR2,SCAMP3,C1orf112,TCF3,BRAP,BLM,FOXO3,RAB11A,MAD2L2,TMCC3,GTF2F1,PIP5K1C,MAT2B,PTEN,CRAT,AHSA1,CENPJ,PRC1,UPF2,COPS7B,CNOT6L,CREB1,UBE2M,NCOA2,SMC4,TSHZ1,NET1,NEK7,DENND1B,DENND4C,ILF3,PARP4,TBRG4,ANAPC2,RHOT1,MARK2,TSR2,PRDX1,PLD3,FBXO21,GNA12,PFDN4,TTLL4,PRDX3,SLC38A7,MFAP1,TFDP1,KHSRP,BRWD3,ESYT2,MIB2,IER2,UBE2E2,SKA3,PLXNC1,ST13,DCAF15,NF1,FLYWCH2,ZNF107,AGFG1,SIRT2,KIF2C,FKBP2,USP48,UBQLN2,MAPK14,BECN1,SNAPC4,RNF103,BCAT2,MBD4,UBLCP1,ZNF804A,RAP1A,EIF4A3,THADA,PPP1R12C,SRI,KIF22,JOSD1,RP2,OGG1,ARID4A,TRIM14,COPS8,FYTTD1,TRIM8,SLC16A7,RRM2,WDR82,SLC25A22,SOX4,STK17B,UBTF,CXXC4,PAF1,GEMIN5,UEVLD,PQBP1,ATXN2L,IARS2,GALNT10,COPS6,STARD3NL,SLC12A7,PIGN,TM9SF4,CIB1,MED13L,TIA1,MEF2A,XPO7,EPHX2,RHBDD1,NFATC3,ZNF449,ZNF335,KIFAP3,BCL2,KNTC1,UBE3C,N4BP2,ALDH9A1,ZNF189,TSTA3,CIC,OXR1,SEPT7,CAND1,GNAS,TSC1,RBM25,ODF2,EXOC4,PITPNA,NUP62,NANP,RBBP4,MZT2B,PTDSS1,C7orf26,SMARCD1,WASF2,MBD1,TMEM106C,ASH1L,GNPNAT1,WDYHV1,HNRNPUL2,PLAGL2,TWF2,CHD1,CCDC50,SAR1A,AKAP8,APOOL,CHTOP,FAM3A,PDIA6,SCYL3,ABI1,MOSPD1,RLIM,ZNF500,NLN,WIPF1,TOR1AIP2,PEF1,BTBD1,RAD54B,DAP3,TMEM41A,TAB2,TULP3,WDR59,CANT1,SCARB1,GAS2,USP11,AKNA,SMURF1,TSPAN5,PPP2R2D,CBX4,KIF3B,CDS2,MAGEH1,SH2D3A,CASP6,EYA1,TOR3A,DBF4,LETMD1,RGS1,HDDC2,MAN1A1,FBXO5,GART,CTNNBL1,TANK,BRD7,YIF1B,TTC17,MRPL11,GINS1,TELO2,CSNK1G2,ADAM17,HMGN1,NASP,ASPM,PRKAR1B,WDR81,MEN1,ZNF407,SYMPK,MFN2,MAPK3,ATAD2,ZNF330,COX8A,KBTBD7,ZRANB2,SRSF3,MBD6,TATDN1,PREPL,IDH3B |
| 3.274e-02 | -3.42 | GSE21678_WT_VS_FOXO1_FOXO3_KO_TREG_DN | MSigDB lists | GSE21678_WT_VS_FOXO1_FOXO3_KO_TREG_DN | 170 | 35 | 17377 | 2626 |
KDM4A,PHRF1,SCYL1,SLC2A1,PXMP2,LIN9,FARSA,CYHR1,PDK2,GART,COQ4,CD3EAP,MSH6,WDR41,NIPSNAP1,PPAN,ABCF2,HNRNPF,TBRG4,FAM50B,FANCE,CHAF1A,AKAP1,MAGED2,TIMM13,ST3GAL2,TRIM32,MYO9A,PDCD11,UNC13C,CHID1,IPO4,RAD51D,BYSL,ZNF511 |
| 3.280e-02 | -3.42 | negative regulation of epidermal growth factor receptor signaling pathway | biological process | GO:0042059 | 45 | 12 | 17256 | 2622 |
PTPN2,HGS,CDC42,RPS27A,RAB7A,SOCS4,EPN1,NUP62,PSEN1,STAM,VPS25,SOCS5 |
| 3.285e-02 | -3.42 | Regulation of activated PAK-2p34 by proteasome mediated degradation | REACTOME pathways | R-HSA-211733 | 51 | 14 | 10287 | 1696 |
PSMD2,PSMD1,PSMA6,PSMA8,RPS27A,PSMD8,PSMD3,PSMB7,PSMA1,PSMB9,PSMD9,PSMC1,PSMB3,PSMC4 |
| 3.287e-02 | -3.42 | GO_NUCLEOPHAGY | MSigDB lists | GO_NUCLEOPHAGY | 17 | 6 | 17377 | 2626 |
ATG2B,WIPI2,BECN1,ATG9A,ATG3,ATG4A |
| 3.287e-02 | -3.42 | REACTOME_DEADENYLATION_OF_MRNA | MSigDB lists | REACTOME_DEADENYLATION_OF_MRNA | 17 | 6 | 17377 | 2626 |
CNOT6,EIF4A3,PARN,PABPC1,PAIP1,CNOT3 |
| 3.287e-02 | -3.42 | GO_CHROMATIN_DISASSEMBLY | MSigDB lists | GO_CHROMATIN_DISASSEMBLY | 17 | 6 | 17377 | 2626 |
SMARCA4,ARID1A,SMARCE1,ARID2,SMARCD1,SUPT16H |
| 3.287e-02 | -3.42 | SA_PTEN_PATHWAY | MSigDB lists | SA_PTEN_PATHWAY | 17 | 6 | 17377 | 2626 |
PDPK1,SHC1,PTEN,MAPK1,AKT2,MAPK3 |
| 3.287e-02 | -3.42 | GO_REGULATION_OF_EXOSOMAL_SECRETION | MSigDB lists | GO_REGULATION_OF_EXOSOMAL_SECRETION | 17 | 6 | 17377 | 2626 |
CHMP2A,HGS,PDCD6IP,VPS4A,STAM,RAB7A |
| 3.287e-02 | -3.42 | SUZUKI_RESPONSE_TO_TSA | MSigDB lists | SUZUKI_RESPONSE_TO_TSA | 17 | 6 | 17377 | 2626 |
ARFIP2,TRIM32,PPP1R12A,GNAI2,TFDP1,RAD23B |
| 3.287e-02 | -3.42 | BIOCARTA_UCALPAIN_PATHWAY | MSigDB lists | BIOCARTA_UCALPAIN_PATHWAY | 17 | 6 | 17377 | 2626 |
EZR,RHOA,RAC1,CAPN1,ITGB1,SPTAN1 |
| 3.287e-02 | -3.42 | GO_RNA_POLYMERASE_CORE_ENZYME_BINDING | MSigDB lists | GO_RNA_POLYMERASE_CORE_ENZYME_BINDING | 17 | 6 | 17377 | 2626 |
PAF1,ELP4,CTR9,RPRD1B,CDC73,ZNF326 |
| 3.287e-02 | -3.42 | GO_PROTEIN_DNA_COMPLEX_DISASSEMBLY | MSigDB lists | GO_PROTEIN_DNA_COMPLEX_DISASSEMBLY | 17 | 6 | 17377 | 2626 |
SMARCA4,ARID1A,SMARCE1,ARID2,SMARCD1,SUPT16H |
| 3.287e-02 | -3.42 | MYLLYKANGAS_AMPLIFICATION_HOT_SPOT_23 | MSigDB lists | MYLLYKANGAS_AMPLIFICATION_HOT_SPOT_23 | 17 | 6 | 17377 | 2626 |
PCSK7,POU2AF1,ARHGEF12,MEN1,BIRC3,PICALM |
| 3.287e-02 | -3.42 | REACTOME_SIGNALING_BY_CONSTITUTIVELY_ACTIVE_EGFR | MSigDB lists | REACTOME_SIGNALING_BY_CONSTITUTIVELY_ACTIVE_EGFR | 17 | 6 | 17377 | 2626 |
KRAS,NRAS,SHC1,RPS27A,HRAS,CDC37 |
| 3.287e-02 | -3.42 | GO_NEGATIVE_REGULATION_OF_CELL_AGING | MSigDB lists | GO_NEGATIVE_REGULATION_OF_CELL_AGING | 17 | 6 | 17377 | 2626 |
MIF,BCL2L12,PTEN,FOXM1,PRKDC,TERF2 |
| 3.287e-02 | -3.42 | BIOCARTA_HCMV_PATHWAY | MSigDB lists | BIOCARTA_HCMV_PATHWAY | 17 | 6 | 17377 | 2626 |
RB1,CREB1,MAPK14,MAPK1,MAP2K2,MAPK3 |
| 3.287e-02 | -3.42 | GO_NEGATIVE_REGULATION_OF_CELL_KILLING | MSigDB lists | GO_NEGATIVE_REGULATION_OF_CELL_KILLING | 17 | 6 | 17377 | 2626 |
HLA-B,PPP3CB,ARRB2,HLA-E,HLA-A,TAP1 |
| 3.287e-02 | -3.42 | GO_PORE_COMPLEX | MSigDB lists | GO_PORE_COMPLEX | 17 | 6 | 17377 | 2626 |
BAK1,NUP62,BCL2,TOMM40,VDAC1,VDAC2 |
| 3.287e-02 | -3.42 | GO_K63_LINKED_POLYUBIQUITIN_BINDING | MSigDB lists | GO_K63_LINKED_POLYUBIQUITIN_BINDING | 17 | 6 | 17377 | 2626 |
TNFAIP3,ZRANB1,TAB2,PARP10,RNF169,OPTN |
| 3.287e-02 | -3.42 | MODULE_492 | MSigDB lists | MODULE_492 | 17 | 6 | 17377 | 2626 |
ASAH1,CTSA,ATP6V1C1,ATP6V1B2,HEXA,HEXB |
| 3.287e-02 | -3.42 | MODULE_346 | MSigDB lists | MODULE_346 | 17 | 6 | 17377 | 2626 |
ASAH1,PSAP,HEXA,GM2A,HEXB,GPX4 |
| 3.287e-02 | -3.42 | GO_PROTEIN_LOCALIZATION_TO_LYSOSOME | MSigDB lists | GO_PROTEIN_LOCALIZATION_TO_LYSOSOME | 17 | 6 | 17377 | 2626 |
NAGPA,SCARB2,GCC2,HGS,CD81,RAB7A |
| 3.287e-02 | -3.42 | GO_NUCLEOSOME_DISASSEMBLY | MSigDB lists | GO_NUCLEOSOME_DISASSEMBLY | 17 | 6 | 17377 | 2626 |
SMARCA4,ARID1A,SMARCE1,ARID2,SMARCD1,SUPT16H |
| 3.287e-02 | -3.42 | GO_POSITIVE_REGULATION_OF_MITOCHONDRIAL_MEMBRANE_PERMEABILITY | MSigDB lists | GO_POSITIVE_REGULATION_OF_MITOCHONDRIAL_MEMBRANE_PERMEABILITY | 17 | 6 | 17377 | 2626 |
MOAP1,HEBP2,RHOT1,RHOT2,ATF2,EYA2 |
| 3.287e-02 | -3.42 | GO_PHAGOCYTIC_CUP | MSigDB lists | GO_PHAGOCYTIC_CUP | 17 | 6 | 17377 | 2626 |
CORO1A,CDC42SE2,TRIP10,RAC1,PIP5K1C,DNM2 |
| 3.287e-02 | -3.42 | BIOCARTA_ARF_PATHWAY | MSigDB lists | BIOCARTA_ARF_PATHWAY | 17 | 6 | 17377 | 2626 |
RB1,MDM2,POLR1B,RAC1,CDKN2A,E2F1 |
| 3.287e-02 | -3.42 | SA_TRKA_RECEPTOR | MSigDB lists | SA_TRKA_RECEPTOR | 17 | 6 | 17377 | 2626 |
RHOA,SHC1,ELK1,AKT2,MAP2K2,HRAS |
| 3.287e-02 | -3.42 | BIOCARTA_ARAP_PATHWAY | MSigDB lists | BIOCARTA_ARAP_PATHWAY | 17 | 6 | 17377 | 2626 |
CYTH1,ASAP2,ARF1,COPA,CLTB,KDELR1 |
| 3.291e-02 | -3.41 | TRIM52 (tripartite motif containing 52) | protein interactions | 84851 | 5 | 3 | 17029 | 2761 |
TRIM41,APP,RNF114 |
| 3.291e-02 | -3.41 | TSNARE1 (t-SNARE domain containing 1) | protein interactions | 203062 | 5 | 3 | 17029 | 2761 |
NDE1,SNAP29,LMNA |
| 3.291e-02 | -3.41 | MBTPS2 (membrane bound transcription factor peptidase, site 2) | protein interactions | 51360 | 5 | 3 | 17029 | 2761 |
SARAF,SYVN1,FAM8A1 |
| 3.291e-02 | -3.41 | MTCP1 (mature T cell proliferation 1) | protein interactions | 4515 | 5 | 3 | 17029 | 2761 |
EWSR1,AKT2,APP |
| 3.291e-02 | -3.41 | HSF2BP (heat shock transcription factor 2 binding protein) | protein interactions | 11077 | 5 | 3 | 17029 | 2761 |
UPF2,UBE2I,CDC73 |
| 3.291e-02 | -3.41 | BCL9L (B cell CLL/lymphoma 9 like) | protein interactions | 283149 | 5 | 3 | 17029 | 2761 |
EWSR1,CDC73,SRPK2 |
| 3.291e-02 | -3.41 | GSTT2B (glutathione S-transferase theta 2B (gene/pseudogene)) | protein interactions | 653689 | 5 | 3 | 17029 | 2761 |
SIRT2,SPDL1,NMD3 |
| 3.291e-02 | -3.41 | NKG7 (natural killer cell granule protein 7) | protein interactions | 4818 | 5 | 3 | 17029 | 2761 |
GORAB,AGTRAP,LMNA |
| 3.291e-02 | -3.41 | CPPED1 (calcineurin like phosphoesterase domain containing 1) | protein interactions | 55313 | 5 | 3 | 17029 | 2761 |
MCM2,POT1,PICALM |
| 3.291e-02 | -3.41 | CYP4V2 (cytochrome P450 family 4 subfamily V member 2) | protein interactions | 285440 | 5 | 3 | 17029 | 2761 |
ZNF420,GATC,LYN |
| 3.291e-02 | -3.41 | C1orf116 (chromosome 1 open reading frame 116) | protein interactions | 79098 | 5 | 3 | 17029 | 2761 |
HOMER1,SMAD2,APP |
| 3.291e-02 | -3.41 | NBEAL2 (neurobeachin like 2) | protein interactions | 23218 | 5 | 3 | 17029 | 2761 |
YWHAZ,ELL2,QSOX2 |
| 3.291e-02 | -3.41 | RGL1 (ral guanine nucleotide dissociation stimulator like 1) | protein interactions | 23179 | 5 | 3 | 17029 | 2761 |
RIT1,APP,HRAS |
| 3.291e-02 | -3.41 | SESN1 (sestrin 1) | protein interactions | 27244 | 5 | 3 | 17029 | 2761 |
KEAP1,RBX1,PRDX1 |
| 3.291e-02 | -3.41 | K2 (interleukin-6) | protein interactions | 4961449 | 5 | 3 | 17029 | 2761 |
PRKCSH,IL6ST,HADHB |
| 3.291e-02 | -3.41 | C6orf118 (chromosome 6 open reading frame 118) | protein interactions | 168090 | 5 | 3 | 17029 | 2761 |
PCM1,SGF29,APP |
| 3.291e-02 | -3.41 | SLC52A2 (solute carrier family 52 member 2) | protein interactions | 79581 | 5 | 3 | 17029 | 2761 |
ADRB2,CDC23,SPPL2B |
| 3.291e-02 | -3.41 | DCLK2 (doublecortin like kinase 2) | protein interactions | 166614 | 5 | 3 | 17029 | 2761 |
KRAS,TSC22D3,DCTN1 |
| 3.291e-02 | -3.41 | K4 (interleukin 8-like CC chemokine) | protein interactions | 4961514 | 5 | 3 | 17029 | 2761 |
PRPF4,TRIM41,PRPF3 |
| 3.291e-02 | -3.41 | Blzf1 (basic leucine zipper nuclear factor 1) | protein interactions | 66352 | 5 | 3 | 17029 | 2761 |
GORASP2,RHEB,RHEBL1 |
| 3.291e-02 | -3.41 | FA2H (fatty acid 2-hydroxylase) | protein interactions | 79152 | 5 | 3 | 17029 | 2761 |
UBQLN4,ERLIN1,LMNA |
| 3.291e-02 | -3.41 | HAS1 (hyaluronan synthase 1) | protein interactions | 3036 | 5 | 3 | 17029 | 2761 |
EWSR1,MCM2,VHL |
| 3.291e-02 | -3.41 | RBBP9 (RB binding protein 9, serine hydrolase) | protein interactions | 10741 | 5 | 3 | 17029 | 2761 |
TERF2IP,RB1,RBL1 |
| 3.291e-02 | -3.41 | SYNE3 (spectrin repeat containing nuclear envelope family member 3) | protein interactions | 161176 | 5 | 3 | 17029 | 2761 |
APP,LUC7L2,KBTBD7 |
| 3.291e-02 | -3.41 | Mtor (mechanistic target of rapamycin kinase) | protein interactions | 56717 | 5 | 3 | 17029 | 2761 |
FKBP1A,DDB1,MLST8 |
| 3.291e-02 | -3.41 | Pax3 (paired box 3) | protein interactions | 18505 | 5 | 3 | 17029 | 2761 |
TRIM28,CIB1,CBX3 |
| 3.291e-02 | -3.41 | STAC2 (SH3 and cysteine rich domain 2) | protein interactions | 342667 | 5 | 3 | 17029 | 2761 |
ATXN1,BRCA1,LMNA |
| 3.291e-02 | -3.41 | PGR (progesterone receptor) | protein interactions | 396198 | 5 | 3 | 17029 | 2761 |
HSPA4,DNAJB1,PTGES3 |
| 3.291e-02 | -3.41 | E1A (alternative splicing utilizing nonconserved sites may produce additional proteins) | protein interactions | 1460853 | 5 | 3 | 17029 | 2761 |
CDKN1B,SMAD2,SMAD1 |
| 3.291e-02 | -3.41 | Aif1l (allograft inflammatory factor 1-like) | protein interactions | 108897 | 5 | 3 | 17029 | 2761 |
THRAP3,PCBP1,PCBP2 |
| 3.291e-02 | -3.41 | TRNAU1AP (tRNA selenocysteine 1 associated protein 1) | protein interactions | 54952 | 5 | 3 | 17029 | 2761 |
BRCA1,PRPF39,CAND1 |
| 3.291e-02 | -3.41 | ADCY8 (adenylate cyclase 8) | protein interactions | 114 | 5 | 3 | 17029 | 2761 |
PPP2CA,CALM2,KRAS |
| 3.291e-02 | -3.41 | PCP4 (Purkinje cell protein 4) | protein interactions | 5121 | 5 | 3 | 17029 | 2761 |
TERF2IP,POT1,TERF1 |
| 3.291e-02 | -3.41 | Haus8 (4HAUS augmin-like complex, subunit 8) | protein interactions | 76478 | 5 | 3 | 17029 | 2761 |
HJURP,WDR18,MKI67 |
| 3.291e-02 | -3.41 | ACSS2 (acyl-CoA synthetase short chain family member 2) | protein interactions | 55902 | 5 | 3 | 17029 | 2761 |
CTR9,UPF1,MAT2A |
| 3.291e-02 | -3.41 | HLA-H (major histocompatibility complex, class I, H (pseudogene)) | protein interactions | 3136 | 5 | 3 | 17029 | 2761 |
HLA-B,HLA-E,CUL3 |
| 3.291e-02 | -3.41 | AMPD1 (adenosine monophosphate deaminase 1) | protein interactions | 270 | 5 | 3 | 17029 | 2761 |
CUL1,CAND1,CUL3 |
| 3.291e-02 | -3.41 | KIAA2026 (KIAA2026) | protein interactions | 158358 | 5 | 3 | 17029 | 2761 |
ATXN1,CREB1,CDC42 |
| 3.291e-02 | -3.41 | OCIAD2 (OCIA domain containing 2) | protein interactions | 132299 | 5 | 3 | 17029 | 2761 |
MCM2,APP,ILF3 |
| 3.291e-02 | -3.41 | NRL (neural retina leucine zipper) | protein interactions | 4901 | 5 | 3 | 17029 | 2761 |
EDF1,FIZ1,OPTN |
| 3.291e-02 | -3.41 | KCTD18 (potassium channel tetramerization domain containing 18) | protein interactions | 130535 | 5 | 3 | 17029 | 2761 |
COPS6,APP,CUL3 |
| 3.291e-02 | -3.41 | GPT (glutamic--pyruvic transaminase) | protein interactions | 2875 | 5 | 3 | 17029 | 2761 |
SASS6,CAPN1,CFL1 |
| 3.291e-02 | -3.41 | FBXW9 (F-box and WD repeat domain containing 9) | protein interactions | 84261 | 5 | 3 | 17029 | 2761 |
CUL1,COPS6,APP |
| 3.291e-02 | -3.41 | MSI1 (musashi RNA binding protein 1) | protein interactions | 4440 | 5 | 3 | 17029 | 2761 |
TARDBP,APP,AGO2 |
| 3.291e-02 | -3.41 | METTL14 (methyltransferase like 14) | protein interactions | 57721 | 5 | 3 | 17029 | 2761 |
METTL3,TACC3,SNX15 |
| 3.291e-02 | -3.41 | Safb (scaffold attachment factor B) | protein interactions | 64196 | 5 | 3 | 17029 | 2761 |
TRA2B,SRSF6,SRSF1 |
| 3.291e-02 | -3.41 | TET3 (tet methylcytosine dioxygenase 3) | protein interactions | 200424 | 5 | 3 | 17029 | 2761 |
LTN1,APP,DDB1 |
| 3.291e-02 | -3.41 | Ppp5c (protein phosphatase 5, catalytic subunit) | protein interactions | 19060 | 5 | 3 | 17029 | 2761 |
CPNE1,CDC16,CDC27 |
| 3.291e-02 | -3.41 | LAIR1 (leukocyte associated immunoglobulin like receptor 1) | protein interactions | 3903 | 5 | 3 | 17029 | 2761 |
CSK,APP,PTPN11 |
| 3.291e-02 | -3.41 | NCBP2-AS2 (NCBP2 antisense RNA 2 (head to head)) | protein interactions | 152217 | 5 | 3 | 17029 | 2761 |
KRAS,CDK2,RBM8A |
| 3.291e-02 | -3.41 | ORF48 (ORF48) | protein interactions | 4961458 | 5 | 3 | 17029 | 2761 |
ANKRD28,PPP6R2,PPP6R1 |
| 3.291e-02 | -3.41 | STAB2 (stabilin 2) | protein interactions | 55576 | 5 | 3 | 17029 | 2761 |
MAPK1,MAPK14,MAPK3 |
| 3.291e-02 | -3.41 | CD300E (CD300e molecule) | protein interactions | 342510 | 5 | 3 | 17029 | 2761 |
PKD2,ATF6,SPPL2B |
| 3.291e-02 | -3.41 | SASH3 (SAM and SH3 domain containing 3) | protein interactions | 54440 | 5 | 3 | 17029 | 2761 |
SMURF1,SMAD4,APP |
| 3.291e-02 | -3.41 | DPYS (dihydropyrimidinase) | protein interactions | 1807 | 5 | 3 | 17029 | 2761 |
DPYSL2,TMEM41B,DPYSL3 |
| 3.291e-02 | -3.41 | COX6A2 (cytochrome c oxidase subunit 6A2) | protein interactions | 1339 | 5 | 3 | 17029 | 2761 |
POT1,APP,MRPL12 |
| 3.291e-02 | -3.41 | C16orf72 (chromosome 16 open reading frame 72) | protein interactions | 29035 | 5 | 3 | 17029 | 2761 |
KRAS,UNK,HUWE1 |
| 3.291e-02 | -3.41 | IGHG4 (immunoglobulin heavy constant gamma 4 (G4m marker)) | protein interactions | 3503 | 5 | 3 | 17029 | 2761 |
SNX27,MCM2,RAD51AP1 |
| 3.291e-02 | -3.41 | FAM78B (family with sequence similarity 78 member B) | protein interactions | 149297 | 5 | 3 | 17029 | 2761 |
ANKRD13D,RPS27A,MAD2L2 |
| 3.291e-02 | -3.41 | MSC (musculin) | protein interactions | 9242 | 5 | 3 | 17029 | 2761 |
TCF12,EWSR1,TCF3 |
| 3.291e-02 | -3.41 | ADRA2B (adrenoceptor alpha 2B) | protein interactions | 151 | 5 | 3 | 17029 | 2761 |
PPP1R9B,YWHAZ,GNAI2 |
| 3.295e-02 | -3.41 | Thyroid cancer | KEGG pathways | ko05216 | 29 | 9 | 7161 | 1149 |
NRAS,CCDC6,KRAS,TFG,MAPK1,HRAS,MAP2K2,RXRB,MAPK3 |
| 3.295e-02 | -3.41 | Thyroid cancer | KEGG pathways | hsa05216 | 29 | 9 | 7161 | 1149 |
NRAS,CCDC6,KRAS,TFG,MAPK1,HRAS,MAP2K2,RXRB,MAPK3 |
| 3.300e-02 | -3.41 | skin-benign_melanocytic_nevus-congenital | COSMIC cancer mutations | skin-benign_melanocytic_nevus-congenital | 9 | 4 | 17385 | 2587 |
FGFR3,KRAS,NRAS,HRAS |
| 3.300e-02 | -3.41 | frontotemporal | COSMIC cancer mutations | frontotemporal | 9 | 4 | 17385 | 2587 |
CDKN2C,H3F3A,PTEN,CDKN2A |
| 3.300e-02 | -3.41 | skin-mucosal-malignant_melanoma-nodular | COSMIC cancer mutations | skin-mucosal-malignant_melanoma-nodular | 9 | 4 | 17385 | 2587 |
KRAS,NRAS,HRAS,CDKN2A |
| 3.300e-02 | -3.41 | breast-extramammary-carcinoma_in_situ-ductal_carcinoma_in_situ | COSMIC cancer mutations | breast-extramammary-carcinoma_in_situ-ductal_carcinoma_in_situ | 9 | 4 | 17385 | 2587 |
KRAS,DNMT3A,NRAS,HRAS |
| 3.300e-02 | -3.41 | skin-other-seborrhoeic_keratosis | COSMIC cancer mutations | skin-other-seborrhoeic_keratosis | 9 | 4 | 17385 | 2587 |
FGFR3,HRAS,CDKN2A,PTPN11 |
| 3.300e-02 | -3.41 | skin-chest-malignant_melanoma-superficial_spreading | COSMIC cancer mutations | skin-chest-malignant_melanoma-superficial_spreading | 9 | 4 | 17385 | 2587 |
KRAS,NRAS,HRAS,CDKN2A |
| 3.300e-02 | -3.41 | peritoneum-mesothelioma-epithelial | COSMIC cancer mutations | peritoneum-mesothelioma-epithelial | 9 | 4 | 17385 | 2587 |
KRAS,EWSR1,PTEN,CDKN2A |
| 3.300e-02 | -3.41 | central_nervous_system-frontal_lobe-glioma-astrocytoma_Grade_II | COSMIC cancer mutations | central_nervous_system-frontal_lobe-glioma-astrocytoma_Grade_II | 9 | 4 | 17385 | 2587 |
KRAS,H3F3A,PTEN,CDKN2A |
| 3.300e-02 | -3.41 | haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-acute_leukaemia_of_ambiguous_lineage_associated_with_MDS | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-haematopoietic_neoplasm-acute_leukaemia_of_ambiguous_lineage_associated_with_MDS | 9 | 4 | 17385 | 2587 |
KRAS,NRAS,HRAS,PTPN11 |
| 3.300e-02 | -3.41 | pancreas-ampulla_of_Vater-carcinoma | COSMIC cancer mutations | pancreas-ampulla_of_Vater-carcinoma | 9 | 4 | 17385 | 2587 |
KRAS,STK11,NRAS,HRAS |
| 3.300e-02 | -3.41 | extramammary | COSMIC cancer mutations | extramammary | 9 | 4 | 17385 | 2587 |
KRAS,DNMT3A,NRAS,HRAS |
| 3.300e-02 | -3.41 | central_nervous_system-frontal_lobe-glioma-oligodendroglioma_Grade_III | COSMIC cancer mutations | central_nervous_system-frontal_lobe-glioma-oligodendroglioma_Grade_III | 9 | 4 | 17385 | 2587 |
CDKN2C,CDKN2A,MSH6,MSH2 |
| 3.300e-02 | -3.41 | prostate-carcinoma-small_cell_carcinoma | COSMIC cancer mutations | prostate-carcinoma-small_cell_carcinoma | 9 | 4 | 17385 | 2587 |
RB1,KRAS,NRAS,HRAS |
| 3.300e-02 | -3.41 | acute_leukaemia_of_ambiguous_lineage_associated_with_MDS | COSMIC cancer mutations | acute_leukaemia_of_ambiguous_lineage_associated_with_MDS | 9 | 4 | 17385 | 2587 |
KRAS,NRAS,HRAS,PTPN11 |
| 3.306e-02 | -3.41 | anus | COSMIC cancer mutations | anus | 13 | 5 | 17385 | 2587 |
KRAS,EWSR1,NRAS,HRAS,CDKN2A |
| 3.306e-02 | -3.41 | skin-scalp-malignant_melanoma-nodular | COSMIC cancer mutations | skin-scalp-malignant_melanoma-nodular | 13 | 5 | 17385 | 2587 |
KRAS,NRAS,PTEN,HRAS,CDKN2A |
| 3.306e-02 | -3.41 | giant_cell_tumour | COSMIC cancer mutations | giant_cell_tumour | 13 | 5 | 17385 | 2587 |
FUS,EWSR1,H3F3A,HRAS,PTPN11 |
| 3.306e-02 | -3.41 | skin-back-carcinoma-basal_cell_carcinoma | COSMIC cancer mutations | skin-back-carcinoma-basal_cell_carcinoma | 13 | 5 | 17385 | 2587 |
FGFR3,KRAS,CYLD,NRAS,HRAS |
| 3.306e-02 | -3.41 | ovary-adenoma-mucinous | COSMIC cancer mutations | ovary-adenoma-mucinous | 13 | 5 | 17385 | 2587 |
GNAS,KRAS,BRCA1,NRAS,CDKN2A |
| 3.306e-02 | -3.41 | radius | COSMIC cancer mutations | radius | 13 | 5 | 17385 | 2587 |
GNAS,KRAS,EWSR1,H3F3A,CDKN2A |
| 3.306e-02 | -3.41 | Brenner_tumour | COSMIC cancer mutations | Brenner_tumour | 13 | 5 | 17385 | 2587 |
FGFR3,KRAS,BRCA1,CYLD,CDKN2A |
| 3.316e-02 | -3.41 | Anchoring of the basal body to the plasma membrane | REACTOME pathways | R-HSA-5620912 | 100 | 24 | 10287 | 1696 |
PLK1,FGFR1OP,NPHP4,MAPRE1,DYNLL1,DCTN2,TMEM216,HAUS4,RAB3IP,PRKACA,RAB11A,HAUS2,HAUS8,RAB8A,PCM1,CCP110,CENPJ,ODF2,SSNA1,CEP63,NDE1,CSNK1D,TUBB,DCTN1 |
| 3.316e-02 | -3.41 | GGCNNMSMYNTTG_UNKNOWN | MSigDB lists | GGCNNMSMYNTTG_UNKNOWN | 71 | 17 | 17377 | 2626 |
ELOVL5,NASP,REPS2,MIOS,WDR13,WDR81,UBE4B,RAB1A,EIF4G2,MAN1A1,SEC31A,LUC7L3,DDX5,ATP6V0C,YBX1,GEMIN4,CHTOP |
| 3.317e-02 | -3.41 | GSE43955_TH0_VS_TGFB_IL6_IL23_TH17_ACT_CD4_TCELL_60H_UP | MSigDB lists | GSE43955_TH0_VS_TGFB_IL6_IL23_TH17_ACT_CD4_TCELL_60H_UP | 193 | 39 | 17377 | 2626 |
SART1,HNRNPAB,TSC22D3,EYA1,SNRPD3,RNF103,PRNP,GSTK1,INTS7,BCL2,TAGLN2,MRPL48,RNF19A,CREB1,ARL5A,GM2A,ALDH9A1,SLC39A9,BAK1,ERCC1,DEAF1,MLEC,DENND4C,DNAJA1,C9orf40,ODC1,KLF6,PRDX1,RDH11,IDE,DDOST,ACYP1,PSMD8,ATP6V1C1,YWHAH,CD81,C11orf1,EYA2,FAM83G |
| 3.317e-02 | -3.41 | GSE360_T_GONDII_VS_B_MALAYI_HIGH_DOSE_DC_DN | MSigDB lists | GSE360_T_GONDII_VS_B_MALAYI_HIGH_DOSE_DC_DN | 193 | 39 | 17377 | 2626 |
PNISR,ADD1,HLA-E,CAST,ACTR3,KIAA0232,HEXB,TKT,SDC2,MYH9,SLC25A12,TGOLN2,EPHX2,MAPK14,PRNP,CDK5,DAPK1,H2AFY,AHCY,ADCY7,NIPAL3,CSNK1G2,ERF,WDR1,ATXN1,EXOSC9,USP22,CHMP2B,STX16,HHEX,SERTAD2,DUSP3,MAFK,ODF2,LPCAT4,DUSP11,PPP6R2,ZMIZ1,HEXA |
| 3.317e-02 | -3.41 | GSE17721_LPS_VS_CPG_4H_BMDC_UP | MSigDB lists | GSE17721_LPS_VS_CPG_4H_BMDC_UP | 193 | 39 | 17377 | 2626 |
PIGM,PARP12,NKD2,C5orf30,PCSK7,LETMD1,RACGAP1,FAM8A1,CPNE3,MXD1,GTF2F1,PTPN2,ZNF260,AP1M1,MDFIC,AFF1,PLCL2,SGCB,TMEM9,HTRA2,SEH1L,SAP30,VOPP1,PRIM2,SNX2,HEBP2,RFFL,TOR1AIP2,DNAJA1,RDH11,ATP6V1D,RBM25,RBL1,IMPDH1,TMEM219,HMGB2,SMAD1,CLN3,SMAD4 |
| 3.319e-02 | -3.41 | sphingolipid metabolic process | biological process | GO:0006665 | 158 | 33 | 17256 | 2622 |
HEXB,CERK,ASAH1,SUMF1,CREM,PRKD3,ITGB8,GLTP,SPTSSA,ST8SIA2,CLN6,GM2A,HTRA2,CSNK1G2,ELOVL5,PPT1,GALC,GBA,ESYT1,ARSK,NEU1,PPP2CA,ALDH3B1,ORMDL2,CERS6,SAMD8,CTSA,PSAP,SMPD4,B4GALT3,CLN3,HEXA,ESYT2 |
| 3.327e-02 | -3.40 | MAPK6/MAPK4 signaling | REACTOME pathways | R-HSA-5687128 | 90 | 22 | 10287 | 1696 |
PSMA8,AGO2,RAC1,PSMB7,PSMA1,DNAJB1,SEPT7,PRKACA,PSMB9,PSMD9,FOXO3,PSMB3,PSMC4,PSMD2,PSMA6,PSMD1,CDC42,RPS27A,PSMD8,PSMD3,MAPK6,PSMC1 |
| 3.327e-02 | -3.40 | REACTOME_RECYCLING_PATHWAY_OF_L1 | MSigDB lists | REACTOME_RECYCLING_PATHWAY_OF_L1 | 26 | 8 | 17377 | 2626 |
DPYSL2,RPS6KA1,DNM2,AP2B1,EZR,MAPK1,AP2S1,NUMB |
| 3.327e-02 | -3.40 | GO_GOLGI_TO_PLASMA_MEMBRANE_PROTEIN_TRANSPORT | MSigDB lists | GO_GOLGI_TO_PLASMA_MEMBRANE_PROTEIN_TRANSPORT | 26 | 8 | 17377 | 2626 |
GCC2,GOLGA4,SYS1,GOLGA7,NSF,ANK3,MACF1,OPTN |
| 3.327e-02 | -3.40 | WIKMAN_ASBESTOS_LUNG_CANCER_DN | MSigDB lists | WIKMAN_ASBESTOS_LUNG_CANCER_DN | 26 | 8 | 17377 | 2626 |
FKBP1A,LZTR1,FNTA,PRKCSH,PPIG,HMGXB3,PRKACA,MYO5A |
| 3.327e-02 | -3.40 | GO_PROTEIN_K63_LINKED_DEUBIQUITINATION | MSigDB lists | GO_PROTEIN_K63_LINKED_DEUBIQUITINATION | 26 | 8 | 17377 | 2626 |
OTUD5,CYLD,ATXN3,TNFAIP3,BABAM1,USP20,ZRANB1,USP13 |
| 3.327e-02 | -3.40 | WILLIAMS_ESR1_TARGETS_UP | MSigDB lists | WILLIAMS_ESR1_TARGETS_UP | 26 | 8 | 17377 | 2626 |
HMGB2,RNASEH2A,SLC26A2,CCNA2,WDR62,CEP55,SIAH2,FAM83D |
| 3.327e-02 | -3.40 | GO_MICROTUBULE_POLYMERIZATION | MSigDB lists | GO_MICROTUBULE_POLYMERIZATION | 26 | 8 | 17377 | 2626 |
ZNF207,GOLGA2,CENPJ,TUBGCP5,NDE1,TUBGCP2,CSNK1D,FBXO5 |
| 3.327e-02 | -3.40 | GO_NEGATIVE_REGULATION_OF_CHROMOSOME_SEGREGATION | MSigDB lists | GO_NEGATIVE_REGULATION_OF_CHROMOSOME_SEGREGATION | 26 | 8 | 17377 | 2626 |
PLK1,ZNF207,PTTG1,CENPF,CSNK2A1,ESPL1,TERF1,MAD2L2 |
| 3.327e-02 | -3.40 | GCM_DEAF1 | MSigDB lists | GCM_DEAF1 | 26 | 8 | 17377 | 2626 |
MOAP1,RAB14,DEAF1,NAPG,TMEM184B,FBXO9,DCUN1D4,UBQLN2 |
| 3.328e-02 | -3.40 | CDP-diacylglycerol biosynthesis | BIOCYC pathways | HUMAN_PWY-5667 | 19 | 7 | 902 | 157 |
AGPAT3,CDS2,AGPAT2,LCLAT1,LPCAT4,ABHD5,AGPAT1 |
| 3.331e-02 | -3.40 | carcinosarcoma-malignant_mesodermal_mixed_tumour | COSMIC cancer mutations | carcinosarcoma-malignant_mesodermal_mixed_tumour | 36 | 10 | 17385 | 2587 |
RB1,NRAS,NF1,PTEN,SF3B1,MSH2,KRAS,BRCA1,SMAD4,CDKN2A |
| 3.332e-02 | -3.40 | HMG_box_2 | pfam domains | PF09011 | 9 | 4 | 17054 | 2545 |
UBTF,HMGB2,SP100,HMGXB3 |
| 3.332e-02 | -3.40 | Complex1_LYR | pfam domains | PF05347 | 9 | 4 | 17054 | 2545 |
NDUFB9,LYRM4,LYRM2,LYRM1 |
| 3.332e-02 | -3.40 | VHS | pfam domains | PF00790 | 9 | 4 | 17054 | 2545 |
HGS,GGA2,GGA1,STAM |
| 3.332e-02 | -3.40 | HGTP_anticodon | pfam domains | PF03129 | 9 | 4 | 17054 | 2545 |
EPRS,HARS,POLG2,TARS |
| 3.332e-02 | -3.40 | Lactamase_B | pfam domains | PF00753 | 9 | 4 | 17054 | 2545 |
LACTB2,HAGH,MBLAC2,HAGHL |
| 3.332e-02 | -3.40 | Alpha_adaptinC2 | pfam domains | PF02883 | 9 | 4 | 17054 | 2545 |
AP2B1,GGA2,AP1B1,GGA1 |
| 3.332e-02 | -3.40 | MIF4G | pfam domains | PF02854 | 9 | 4 | 17054 | 2545 |
UPF2,MIF4GD,EIF4G2,PAIP1 |
| 3.332e-02 | -3.40 | Rhomboid | pfam domains | PF01694 | 9 | 4 | 17054 | 2545 |
PARL,RHBDD2,RHBDF2,RHBDD1 |
| 3.334e-02 | -3.40 | SASSON_RESPONSE_TO_FORSKOLIN_DN | MSigDB lists | SASSON_RESPONSE_TO_FORSKOLIN_DN | 87 | 20 | 17377 | 2626 |
SRP72,TK1,MAPRE2,TLK1,MAP4K4,RANGAP1,PAWR,CYFIP2,ITGB5,PI4K2A,PTPRF,MAPK6,ADCY9,STAT1,PPP3R1,CAPZA1,DAPK1,ACTB,ADCY7,SMARCD1 |
| 3.338e-02 | -3.40 | BMF (Bcl2 modifying factor) | protein interactions | 90427 | 16 | 6 | 17029 | 2761 |
TCF12,MCL1,BCL2,BCL2L1,DYNLL1,MYO5A |
| 3.338e-02 | -3.40 | VPS35L (VPS35 endosomal protein sorting factor like) | protein interactions | 57020 | 16 | 6 | 17029 | 2761 |
CCDC93,COMMD10,COMMD6,COMMD4,COMMD8,VPS29 |
| 3.338e-02 | -3.40 | TMEM9 (transmembrane protein 9) | protein interactions | 252839 | 16 | 6 | 17029 | 2761 |
SEPT11,PPT1,EYA2,VPS29,MRPL12,TMEM216 |
| 3.338e-02 | -3.40 | OAS3 (2'-5'-oligoadenylate synthetase 3) | protein interactions | 4940 | 16 | 6 | 17029 | 2761 |
LYAR,MAVS,FTSJ3,PABPC4,PPM1G,GTPBP4 |
| 3.338e-02 | -3.40 | Sumo3 (small ubiquitin-like modifier 3) | protein interactions | 20610 | 16 | 6 | 17029 | 2761 |
EXOC3,UPF1,INTS7,TBC1D14,XIAP,UTP15 |
| 3.338e-02 | -3.40 | HIST1H2BK (histone cluster 1 H2B family member k) | protein interactions | 85236 | 16 | 6 | 17029 | 2761 |
CYLD,MCM2,CD81,MCM5,CHD1L,SRPK2 |
| 3.338e-02 | -3.40 | ZC3HAV1L (zinc finger CCCH-type containing, antiviral 1 like) | protein interactions | 92092 | 16 | 6 | 17029 | 2761 |
PTPN2,KRAS,EWSR1,APP,TERF1,TERF2 |
| 3.338e-02 | -3.40 | NCAPG2 (non-SMC condensin II complex subunit G2) | protein interactions | 54892 | 16 | 6 | 17029 | 2761 |
FUS,SMC2,CCP110,CLTB,RAF1,UHRF2 |
| 3.338e-02 | -3.40 | vIRF-1 (interferon regulatory factor) | protein interactions | 4961464 | 16 | 6 | 17029 | 2761 |
USP7,RB1,PAWR,IRF3,RBL1,SDC2 |
| 3.338e-02 | -3.40 | BAZ2A (bromodomain adjacent to zinc finger domain 2A) | protein interactions | 11176 | 16 | 6 | 17029 | 2761 |
RACGAP1,BEND3,DNMT1,TTF1,USP21,IFI16 |
| 3.338e-02 | -3.40 | Trp53bp1 (transformation related protein 53 binding protein 1) | protein interactions | 27223 | 16 | 6 | 17029 | 2761 |
ARHGAP17,PSMD2,MRPL11,ZBTB11,CENPF,WBP2 |
| 3.338e-02 | -3.40 | HOMER2 (homer scaffold protein 2) | protein interactions | 9455 | 16 | 6 | 17029 | 2761 |
KPNA2,HOMER1,VKORC1,SMURF1,APP,UBXN1 |
| 3.338e-02 | -3.40 | GSTA1 (glutathione S-transferase alpha 1) | protein interactions | 2938 | 16 | 6 | 17029 | 2761 |
ZBTB21,SPDL1,GAR1,RPAIN,APP,ACOX1 |
| 3.338e-02 | -3.40 | COMMD7 (COMM domain containing 7) | protein interactions | 149951 | 16 | 6 | 17029 | 2761 |
CCDC93,COMMD10,COMMD6,COMMD4,COMMD8,VPS29 |
| 3.338e-02 | -3.40 | WDR70 (WD repeat domain 70) | protein interactions | 55100 | 16 | 6 | 17029 | 2761 |
UBTF,RBPJ,ARRB2,LMNA,WDR48,SRPK2 |
| 3.338e-02 | -3.40 | HPDL (4-hydroxyphenylpyruvate dioxygenase like) | protein interactions | 84842 | 16 | 6 | 17029 | 2761 |
NUSAP1,TCOF1,STMN1,MECP2,TOR1AIP1,HTRA2 |
| 3.338e-02 | -3.40 | FCGR2B (Fc fragment of IgG receptor IIb) | protein interactions | 2213 | 16 | 6 | 17029 | 2761 |
SHC1,LY6E,MAPK1,LYN,MAPK3,PTPN11 |
| 3.338e-02 | -3.40 | TFB1M (transcription factor B1, mitochondrial) | protein interactions | 51106 | 16 | 6 | 17029 | 2761 |
PTPN2,YWHAH,DCAF8,MECP2,MRPL12,CAND1 |
| 3.338e-02 | -3.40 | ICMT (isoprenylcysteine carboxyl methyltransferase) | protein interactions | 23463 | 16 | 6 | 17029 | 2761 |
KRAS,RHOA,NRAS,HRAS,RAD51D,RAC1 |
| 3.338e-02 | -3.40 | RAC3 (Rac family small GTPase 3) | protein interactions | 5881 | 16 | 6 | 17029 | 2761 |
ARHGDIB,FBXL19,RHOC,NRBP1,RAC1,CIB1 |
| 3.338e-02 | -3.40 | CDSN (corneodesmosin) | protein interactions | 1041 | 16 | 6 | 17029 | 2761 |
VAV1,UBQLN4,CYLD,MPG,UCHL5,CEP55 |
| 3.338e-02 | -3.40 | NOTCH4 (notch 4) | protein interactions | 4855 | 16 | 6 | 17029 | 2761 |
MDM2,RBPJ,SMAD2,MAML1,PSEN1,SMAD4 |
| 3.338e-02 | -3.40 | PLK3 (polo like kinase 3) | protein interactions | 1263 | 16 | 6 | 17029 | 2761 |
CHEK2,BCL2L1,MAPK1,CENPU,CIB1,PRNP |
| 3.338e-02 | -3.40 | INHBE (inhibin subunit beta E) | protein interactions | 83729 | 16 | 6 | 17029 | 2761 |
PRMT7,PTEN,VHL,APP,ANKRD46,MYO1F |
| 3.338e-02 | -3.40 | ENY2 (ENY2, transcription and export complex 2 subunit) | protein interactions | 56943 | 16 | 6 | 17029 | 2761 |
USP22,KAT2A,SGF29,APP,NEIL3,H2AFX |
| 3.338e-02 | -3.40 | PTBP3 (polypyrimidine tract binding protein 3) | protein interactions | 9991 | 16 | 6 | 17029 | 2761 |
NENF,PPWD1,APP,MATR3,ILF3,CDC5L |
| 3.338e-02 | -3.40 | NUPL2 (nucleoporin like 2) | protein interactions | 11097 | 16 | 6 | 17029 | 2761 |
NUP153,GLE1,NUP58,MARK2,RAE1,NUP107 |
| 3.338e-02 | -3.40 | JPT1 (Jupiter microtubule associated homolog 1) | protein interactions | 51155 | 16 | 6 | 17029 | 2761 |
UNK,KPNA2,SEPT9,STMN1,TRIM28,CFL1 |
| 3.338e-02 | -3.40 | FGD1 (FYVE, RhoGEF and PH domain containing 1) | protein interactions | 2245 | 16 | 6 | 17029 | 2761 |
TAP2,CDC42,INTS7,FBXL19,ELMO1,ESYT2 |
| 3.338e-02 | -3.40 | DNALI1 (dynein axonemal light intermediate chain 1) | protein interactions | 7802 | 16 | 6 | 17029 | 2761 |
EIF3K,SIAH1,SESTD1,APP,ACTR3,DNM2 |
| 3.338e-02 | -3.40 | TP53INP1 (tumor protein p53 inducible nuclear protein 1) | protein interactions | 94241 | 16 | 6 | 17029 | 2761 |
E2F2,ASPM,E2F4,HIPK2,E2F1,E2F3 |
| 3.338e-02 | -3.40 | UBL5 (ubiquitin like 5) | protein interactions | 59286 | 16 | 6 | 17029 | 2761 |
CRKL,CAB39,SART1,TXN,COIL,FANCI |
| 3.338e-02 | -3.40 | FLG2 (filaggrin family member 2) | protein interactions | 388698 | 16 | 6 | 17029 | 2761 |
CYLD,JAK1,VDAC1,CDK2,CDC73,TCF3 |
| 3.338e-02 | -3.40 | Trp53 (transformation related protein 53) | protein interactions | 22059 | 16 | 6 | 17029 | 2761 |
SMARCA4,TOPORS,MDM2,PRKAA1,NUMB,HABP4 |
| 3.338e-02 | -3.40 | SGK2 (SGK2, serine/threonine kinase 2) | protein interactions | 10110 | 16 | 6 | 17029 | 2761 |
PDPK1,FKBP5,DDX5,APP,CCT8,ILF3 |
| 3.343e-02 | -3.40 | Septin | pfam domains | PF00735 | 13 | 5 | 17054 | 2545 |
SEPT11,SEPT8,SEPT1,SEPT7,SEPT9 |
| 3.343e-02 | -3.40 | GTP_EFTU_D2 | pfam domains | PF03144 | 13 | 5 | 17054 | 2545 |
GUF1,GFM2,EFTUD2,GSPT2,TUFM |
| 3.343e-02 | -3.40 | OTU | pfam domains | PF02338 | 13 | 5 | 17054 | 2545 |
OTUD5,VCPIP1,OTUD3,ZRANB1,TNFAIP3 |
| 3.343e-02 | -3.40 | UBX | pfam domains | PF00789 | 13 | 5 | 17054 | 2545 |
UBXN2A,UBXN2B,UBXN1,FAF1,NSFL1C |
| 3.345e-02 | -3.40 | membrane lipid metabolic process | biological process | GO:0006643 | 215 | 43 | 17256 | 2622 |
PIGM,PIGN,PIGQ,HEXB,CERK,ASAH1,SUMF1,B4GALT4,CREM,PRKD3,ITGB8,PYURF,PIGG,GLTP,ST8SIA2,SPTSSA,CLN6,GM2A,HTRA2,PGAP2,ELOVL5,CSNK1G2,PIGT,DPM1,PPT1,GALC,GBA,ESYT1,ARSK,NEU1,PPP2CA,ALDH3B1,ORMDL2,CERS6,ST3GAL2,SAMD8,CTSA,SMPD4,PSAP,B4GALT3,CLN3,HEXA,ESYT2 |
| 3.354e-02 | -3.39 | GSE24634_NAIVE_CD4_TCELL_VS_DAY3_IL4_CONV_TREG_UP | MSigDB lists | GSE24634_NAIVE_CD4_TCELL_VS_DAY3_IL4_CONV_TREG_UP | 176 | 36 | 17377 | 2626 |
IER2,MAX,TSC22D3,CAST,CUTA,KLF13,BTN3A1,CDIPT,DAZAP2,RPL11,RABGAP1L,IL6ST,RPL19,PIK3IP1,SLC35C2,SPSB3,ATP6V1G1,GCC2,CYTH1,FAM172A,TNFAIP3,COQ10B,BTG2,ITM2A,SRSF5,RPL36,OPTN,PFDN5,ZNF862,STK38,GADD45B,ARNTL,VCPIP1,IGBP1,PPP2R2D,TOB1 |
| 3.354e-02 | -3.39 | GSE21927_SPLEEN_VS_TUMOR_MONOCYTE_BALBC_DN | MSigDB lists | GSE21927_SPLEEN_VS_TUMOR_MONOCYTE_BALBC_DN | 176 | 36 | 17377 | 2626 |
SNX27,PPP1R2,URB2,TMEM109,TMX3,DHX9,ARID1B,HNRNPA2B1,DTL,RB1,SHC1,MED10,NOC2L,SUCLG2,UBE2M,HDHD2,ARHGAP17,PHF10,NET1,DRAP1,ZMYM5,HNRNPF,TUFM,KDM1B,SUPT16H,CBX3,EPB41,SERTAD2,SYNCRIP,PPM1G,SIAH2,C4orf46,SMAD1,CHPT1,RTN3,SSRP1 |
| 3.354e-02 | -3.39 | GSE19888_ADENOSINE_A3R_INH_PRETREAT_AND_ACT_BY_A3R_VS_TCELL_MEMBRANES_ACT_MAST_CELL_DN | MSigDB lists | GSE19888_ADENOSINE_A3R_INH_PRETREAT_AND_ACT_BY_A3R_VS_TCELL_MEMBRANES_ACT_MAST_CELL_DN | 176 | 36 | 17377 | 2626 |
KRBA1,PDAP1,PCSK7,MXD4,IKBIP,HCFC1R1,PITHD1,REEP5,HMG20A,TUBGCP2,RPL23A,DECR1,PHTF1,RAB4A,TTC4,ALDH18A1,RNF26,LMAN1,GPD1L,CAMK2G,CARM1,KLF10,SLC16A7,MEF2D,PPFIA3,KRTCAP2,GFER,RPL36,DUS3L,PDRG1,PRPS2,H2AFX,ESPL1,COIL,RAD51D,PDCD4 |
| 3.361e-02 | -3.39 | V$MZF1_02 | MSigDB lists | V$MZF1_02 | 222 | 44 | 17377 | 2626 |
GGNBP2,DNMT3A,EWSR1,TRERF1,PPP1R12A,NF1,EYA1,ENSA,SLC25A12,CDK13,SLC4A2,ZADH2,XPR1,FBRS,CSDE1,HNRNPA2B1,VASP,GART,UTP18,SSBP3,TNPO2,CDK12,CGGBP1,LYPLA2,TGFB1,PRRC2A,MTA2,LRRC8A,UBE4B,WDR81,ARID1A,STX16,KLF6,PATL1,CBX3,SUPT16H,PTPRF,EIF3K,TAB2,TFE3,UQCRH,TFDP2,H3F3A,ATXN7L2 |
| 3.363e-02 | -3.39 | GSE41867_NAIVE_VS_DAY8_LCMV_CLONE13_EFFECTOR_CD8_TCELL_DN | MSigDB lists | GSE41867_NAIVE_VS_DAY8_LCMV_CLONE13_EFFECTOR_CD8_TCELL_DN | 159 | 33 | 17377 | 2626 |
CMAS,TOMM20,MOGS,TIA1,BRAP,FKBP2,RPAIN,FBXO3,GOLM1,KDM2A,MAVS,TP53BP2,VOPP1,ARHGAP17,KCTD20,MAP7D1,USP22,MEF2D,FXR1,VKORC1,SMAP2,GNA12,CDCA4,PALB2,SCAP,CAPN7,CANT1,CHMP4B,HMGB2,ZNF830,SAT2,ZC3HC1,TIGD2 |
| 3.363e-02 | -3.39 | GSE40274_CTRL_VS_XBP1_TRANSDUCED_ACTIVATED_CD4_TCELL_UP | MSigDB lists | GSE40274_CTRL_VS_XBP1_TRANSDUCED_ACTIVATED_CD4_TCELL_UP | 159 | 33 | 17377 | 2626 |
SLC12A7,DDX58,UBL3,RHOG,UBE2E2,ANXA6,CASP6,ARID5A,PTP4A3,NOTCH2,ZADH2,PSEN1,PIP4K2A,MLX,SP100,ARL6IP1,CDC25B,LDLRAD3,ABI1,ENPP4,LRP5,PLEC,EDEM2,PICALM,CYB5A,AHNAK,PSAP,PPP6R2,GLCCI1,MYL12B,SMAD4,NAA60,CPEB2 |
| 3.366e-02 | -3.39 | G_TR_CS | interpro domains | IPR031157 | 9 | 4 | 18492 | 2768 |
GUF1,GFM2,GSPT2,TUFM |
| 3.366e-02 | -3.39 | Rhomboid-like_sf | interpro domains | IPR035952 | 9 | 4 | 18492 | 2768 |
PARL,RHBDD2,RHBDD1,RHBDF2 |
| 3.366e-02 | -3.39 | Anticodon-bd | interpro domains | IPR004154 | 9 | 4 | 18492 | 2768 |
EPRS,POLG2,HARS,TARS |
| 3.366e-02 | -3.39 | Peptidase_S54_rhomboid_dom | interpro domains | IPR022764 | 9 | 4 | 18492 | 2768 |
PARL,RHBDD2,RHBDD1,RHBDF2 |
| 3.366e-02 | -3.39 | Importin-a_IBB | interpro domains | IPR002652 | 9 | 4 | 18492 | 2768 |
KPNA2,SNUPN,KPNA4,KPNA1 |
| 3.366e-02 | -3.39 | Complex1_LYR | interpro domains | IPR008011 | 9 | 4 | 18492 | 2768 |
NDUFB9,LYRM4,LYRM2,LYRM1 |
| 3.366e-02 | -3.39 | S1_dom | interpro domains | IPR022967 | 9 | 4 | 18492 | 2768 |
DHX8,POLR2G,PDCD11,EXOSC1 |
| 3.366e-02 | -3.39 | VHS_dom | interpro domains | IPR002014 | 9 | 4 | 18492 | 2768 |
HGS,GGA2,GGA1,STAM |
| 3.366e-02 | -3.39 | Ubox_domain | interpro domains | IPR003613 | 9 | 4 | 18492 | 2768 |
UBE4B,UBE4A,PPIL2,PRPF19 |
| 3.366e-02 | -3.39 | Clathrin_a/b/g-adaptin_app_Ig | interpro domains | IPR008152 | 9 | 4 | 18492 | 2768 |
AP2B1,AP1B1,GGA2,GGA1 |
| 3.367e-02 | -3.39 | pyrimidine nucleoside monophosphate metabolic process | biological process | GO:0009129 | 17 | 6 | 17256 | 2622 |
UPRT,UCK1,DCTD,DUT,HDDC2,UCK2 |
| 3.367e-02 | -3.39 | adaptation of signaling pathway | biological process | GO:0023058 | 17 | 6 | 17256 | 2622 |
ADRB2,GRK2,ARRB2,GTF2H2,RDH11,DNM2 |
| 3.367e-02 | -3.39 | positive regulation of telomere capping | biological process | GO:1904355 | 17 | 6 | 17256 | 2622 |
MAP3K4,AURKB,MAPK1,NEK7,MAPK3,NABP2 |
| 3.367e-02 | -3.39 | copper ion homeostasis | biological process | GO:0055070 | 17 | 6 | 17256 | 2622 |
SLC31A1,ARF1,CUTC,APP,XIAP,PRNP |
| 3.367e-02 | -3.39 | regulation of DNA damage checkpoint | biological process | GO:2000001 | 17 | 6 | 17256 | 2622 |
RFWD3,FEM1B,RPA2,CHEK2,WDR76,THOC1 |
| 3.367e-02 | -3.39 | Notch receptor processing | biological process | GO:0007220 | 17 | 6 | 17256 | 2622 |
YBX1,ADAM17,ADAM10,APH1B,PSEN1,APH1A |
| 3.369e-02 | -3.39 | protein N-linked glycosylation | biological process | GO:0006487 | 92 | 21 | 17256 | 2622 |
DPM1,GORASP1,MOGS,B4GALT1,SYVN1,MCFD2,KRTCAP2,TMEM165,ALG3,RPN1,NUS1,DDOST,MAGT1,STT3A,DAD1,FUT8,ST3GAL2,RPN2,OSTC,LMAN1,MGAT5 |
| 3.378e-02 | -3.39 | PSEN1 (presenilin 1) | protein interactions | 5663 | 112 | 26 | 17029 | 2761 |
UNK,PKP4,ST13,CASP6,APH1A,METTL2A,DHX9,CIB1,ENSA,KRAS,BCL2L1,NOTCH2,PRKACA,PSEN1,APH1B,RAB11A,SPPL2B,APP,RHEB,RAD23A,CDK5,NDUFS8,BCL2,CFL1,PDCD4,CDC37 |
| 3.383e-02 | -3.39 | UBX_dom | interpro domains | IPR001012 | 13 | 5 | 18492 | 2768 |
UBXN2A,UBXN2B,UBXN1,FAF1,NSFL1C |
| 3.383e-02 | -3.39 | EFTu-like_2 | interpro domains | IPR004161 | 13 | 5 | 18492 | 2768 |
GUF1,GFM2,GSPT2,EFTUD2,TUFM |
| 3.383e-02 | -3.39 | Ser/Thr-sp_prot-phosphatase | interpro domains | IPR006186 | 13 | 5 | 18492 | 2768 |
PPP2CA,PPP3CA,PPP3CB,PPP5C,PPP6C |
| 3.383e-02 | -3.39 | G_SEPTIN_dom | interpro domains | IPR030379 | 13 | 5 | 18492 | 2768 |
SEPT8,SEPT11,SEPT1,SEPT7,SEPT9 |
| 3.383e-02 | -3.39 | Septin | interpro domains | IPR016491 | 13 | 5 | 18492 | 2768 |
SEPT8,SEPT11,SEPT1,SEPT7,SEPT9 |
| 3.386e-02 | -3.39 | positive regulation of cellular component biogenesis | biological process | GO:0044089 | 499 | 91 | 17256 | 2622 |
WASF2,RHOG,CHMP2A,PDCD6IP,NPHP4,AGRN,CHD1L,RAC1,ACTR3,MIEN1,BECN1,TWF2,STAM,EEF2K,DLG5,CDC42,RALB,DNM2,CDKN1B,FNIP2,SPIDR,CARMIL1,DCTN1,MLST8,ERCC1,PSRC1,SEPT9,RBX1,NCK1,RAB7A,WIPF1,ANLN,DPYSL3,WAS,IDE,LIMK1,CBLN2,PIEZO1,CLU,ROCK1,VPS4A,SLF1,PSMC1,ATMIN,MAPRE1,MECP2,RHOC,CDT1,FLOT1,KCTD17,NCKAP1,RGS2,DOCK11,PIP4K2A,JMY,SPAG5,RPA2,SUB1,VASP,CCP110,ARPC5,CENPJ,XPA,CREB1,CNOT6L,LRSAM1,GTF2H2,TGFB1,CYFIP1,RHOA,PIP4K2C,UTP15,BCLAF1,SEPT7,ARPC1A,SH3GLB1,RPA1,CAND1,PSMC4,HSPA1B,TSC1,HGS,STX18,ARAP1,NUP62,CNOT6,HRAS,TERF1,SLF2,DDB1,FAF1 |
| 3.386e-02 | -3.39 | ATGTAGC,MIR-221,MIR-222 | MSigDB lists | ATGTAGC,MIR-221,MIR-222 | 131 | 28 | 17377 | 2626 |
TCF12,NSMCE4A,KLC1,CTCF,ATXN1,AGFG1,ARID1A,RAB1A,CBFB,ZADH2,ETS1,PAIP1,ARF4,SLC25A37,PAIP2,VEZF1,ATP1A1,PDCD10,ETS2,RIMS3,PPP6C,OGT,AXIN2,PPP3R1,FOXN2,CDKN1B,GNAI2,PURA |
| 3.396e-02 | -3.38 | NOS3 (nitric oxide synthase 3) | protein interactions | 4846 | 52 | 14 | 17029 | 2761 |
IMMT,ST13,PPP2R5A,GOLGA2,GUCY1B1,CEP55,EXOSC1,ACTB,TECR,H3F3A,PSEN1,APP,CDC37,PI4K2A |
| 3.396e-02 | -3.38 | PAPOLA (poly(A) polymerase alpha) | protein interactions | 10914 | 52 | 14 | 17029 | 2761 |
SMAD2,NRAS,GRK2,UGP2,HUWE1,CORO1C,CIRBP,SIRT2,PABPC1,PICALM,SNRPA,TARS,LMNA,NUDC |
| 3.396e-02 | -3.38 | HOXB5 (homeobox B5) | protein interactions | 3215 | 52 | 14 | 17029 | 2761 |
CSNK1G2,EIF2S2,CTNNBL1,TRIM11,ATP6V0A1,ATP6V0A2,KRAS,ACTB,NUP155,HDGFL2,LYN,C12orf75,HRAS,SVIP |
| 3.396e-02 | -3.38 | DCP1A (decapping mRNA 1A) | protein interactions | 55802 | 52 | 14 | 17029 | 2761 |
CRKL,ZBTB21,PPP1R37,UPF1,KIF13B,AGO2,TRMT6,LSM8,ALDH18A1,PATL1,CCDC59,SMAD4,MAPK3,EDC3 |
| 3.396e-02 | -3.38 | PTH1R (parathyroid hormone 1 receptor) | protein interactions | 5745 | 52 | 14 | 17029 | 2761 |
SLC12A7,PIGM,ABCA3,FAM118B,CERS6,C1orf112,SLC44A1,DNAJC17,AGPAT3,SLC4A2,CLN3,SLC12A9,YWHAH,SPPL2B |
| 3.399e-02 | -3.38 | human chr4q24 | chromosome location | human chr4q24 | 36 | 8 | 26185 | 2809 |
UBE2D3,CXXC4,PPP3CA,MANBA,PPA2,INTS12,CISD2,GSTCD |
| 3.404e-02 | -3.38 | GO_OXIDOREDUCTION_COENZYME_METABOLIC_PROCESS | MSigDB lists | GO_OXIDOREDUCTION_COENZYME_METABOLIC_PROCESS | 98 | 22 | 17377 | 2626 |
GALK1,NADSYN1,MDH2,TKT,LDHA,PFKFB3,ADPGK,OGDH,PDHX,COQ4,PRDX5,DHTKD1,MDH1,GPI,IDH3B,TALDO1,PGAM1,GPD1L,PDSS2,KCNAB2,PFKP,LDHB |
| 3.404e-02 | -3.38 | GO_NEGATIVE_REGULATION_OF_CHROMOSOME_ORGANIZATION | MSigDB lists | GO_NEGATIVE_REGULATION_OF_CHROMOSOME_ORGANIZATION | 98 | 22 | 17377 | 2626 |
ZNF207,PLK1,ERCC1,TRIP12,KDM4A,MECP2,CENPF,PTTG1,CSNK2A1,BRCA1,KDM3A,MAD2L2,XRCC5,TERF2IP,ATAD2,NOC2L,PML,H2AFY,ESPL1,TERF1,DNMT1,TERF2 |
| 3.407e-02 | -3.38 | GO_REGULATION_OF_CANONICAL_WNT_SIGNALING_PATHWAY | MSigDB lists | GO_REGULATION_OF_CANONICAL_WNT_SIGNALING_PATHWAY | 228 | 45 | 17377 | 2626 |
ZBED3,NPHP4,CYLD,XIAP,NKD2,ZNRF3,MAPK14,CSNK1A1,PSMD9,FOXO3,SCYL2,MAD2L2,FZD6,PSMD2,PSMD1,PSMA6,PIN1,AXIN2,DVL2,USP34,RBX1,PSMA8,ASPM,PSMB7,CUL3,PSMA1,LRP5,SOX4,PSMB9,PSMB3,DAPK3,PSMC4,ANKRD10,PFDN5,RPS27A,AXIN1,WNT5B,PSMD3,PSMD8,ARNTL,SIAH2,RBPJ,DVL1,PSMC1,CSNK1D |
| 3.408e-02 | -3.38 | ABC_TRANSPORTER_1 | prosite domains | PS00211 | 44 | 11 | 12060 | 1670 |
ABCA3,ABCC10,ABCF2,TAP1,ABCB10,TAP2,ABCD1,ABCA1,ABCF1,ABCC5,ABCC1 |
| 3.412e-02 | -3.38 | haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-angioimmunoblastic_T_cell_lymphoma | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-angioimmunoblastic_T_cell_lymphoma | 267 | 51 | 17385 | 2587 |
DNMT3A,ARID2,NF1,SF3B1,MUM1,MRPL39,SHPRH,SUZ12,SMARCA4,CTCF,NOTCH2,ETS1,ARID1B,CHD1,DST,IRF4,RB1,CTSS,BRPF3,HUWE1,PTEN,HDAC7,ETV6,PTPN11,PDS5B,BRD7,TTC3,BCL2,STAT3,HP1BP3,NRAS,RHOA,BRD4,CELSR2,TNFAIP3,TACC1,BTG2,MKI67,KRAS,ARID1A,PHF6,FAS,ZMYM3,GNAS,JAK1,STAT6,ACTB,CHEK2,MAPK1,CDKN2A,PARD3 |
| 3.418e-02 | -3.38 | ubiquitin | pfam domains | PF00240 | 41 | 11 | 17054 | 2545 |
UBQLN4,TMUB1,RPS27A,RAD23B,UHRF2,FAU,UBQLN2,HERPUD2,ISG15,UBLCP1,RAD23A |
| 3.420e-02 | -3.38 | V$IRF2_01 | MSigDB lists | V$IRF2_01 | 120 | 26 | 17377 | 2626 |
DDX58,KARS,ASH1L,PLXNC1,TMBIM4,TRMT6,TAP1,E2F3,SREK1,KDM3A,PSMB9,RAPGEF6,USP5,ABHD16A,DDX17,TERF2IP,PRKD3,USF1,DAP3,CCDC6,LSM6,PRDX5,BBX,MAPK6,UPF2,ROCK1 |
| 3.421e-02 | -3.38 | GO_RESPONSE_TO_DSRNA | MSigDB lists | GO_RESPONSE_TO_DSRNA | 66 | 16 | 17377 | 2626 |
DDX58,HNRNPA2B1,SMAD2,DGCR8,RALB,FLOT1,TICAM1,IRF3,MAVS,PRKRA,SMAD1,MAPK1,METTL3,SRRT,ZC3HAV1,MAPK3 |
| 3.421e-02 | -3.38 | GO_ACTIN_FILAMENT | MSigDB lists | GO_ACTIN_FILAMENT | 66 | 16 | 17377 | 2626 |
WDR1,RAC1,EZR,WIPF1,PAWR,MYO9B,MARK2,DAPK3,DPYSL3,TSC1,KEAP1,RCSD1,PKD2,GAS2,CORO1A,MYO5A |
| 3.421e-02 | -3.38 | GO_SOMATIC_STEM_CELL_POPULATION_MAINTENANCE | MSigDB lists | GO_SOMATIC_STEM_CELL_POPULATION_MAINTENANCE | 66 | 16 | 17377 | 2626 |
POLR2I,SMAD2,KLF10,POLR2G,POLR2L,POLR2J,POLR2K,RAF1,LDB1,POLR2D,LRP5,RBPJ,SOX4,STAT3,SMAD4,POLR2A |
| 3.422e-02 | -3.38 | ACTN1 (actinin alpha 1) | protein interactions | 87 | 154 | 34 | 17029 | 2761 |
COX15,MAPRE1,MYH9,PSEN1,GIT2,PARK7,CDC73,CDK5,VASP,MCM5,ZNF746,CYC1,ATF2,TERF2,CSRP1,DCAF8,EZR,PSMA1,CAPZA2,ERBIN,MCM2,ANLN,PDHX,ISG15,PDLIM1,ITGB1,KPNA2,CLU,PDLIM5,CDK2,XRCC4,CD81,TERF1,COIL |
| 3.425e-02 | -3.37 | SET_dom | interpro domains | IPR001214 | 51 | 13 | 18492 | 2768 |
ASH1L,KMT5C,SUV39H2,KMT2E,KMT5A,SETD3,PRDM4,EHMT1,KMT2B,NSD3,EZH1,KMT2C,PRDM11 |
| 3.425e-02 | -3.37 | positive regulation of microtubule polymerization | biological process | GO:0031116 | 26 | 8 | 17256 | 2622 |
PSRC1,MAPRE1,MECP2,RAC1,CDKN1B,RGS2,HSPA1B,DCTN1 |
| 3.425e-02 | -3.37 | cargo loading into vesicle | biological process | GO:0035459 | 26 | 8 | 17256 | 2622 |
SEC31A,TMED10,SAR1A,SEC24C,MIA2,RAB1A,PICALM,TMED2 |
| 3.425e-02 | -3.37 | modulation by virus of host process | biological process | GO:0019054 | 26 | 8 | 17256 | 2622 |
CCNK,TGFB1,KPNA4,KPNA1,KPNA2,BCL2L1,EIF2AK4,CPSF4 |
| 3.425e-02 | -3.37 | positive regulation of lamellipodium organization | biological process | GO:1902745 | 26 | 8 | 17256 | 2622 |
WASF2,NCKAP1,CDC42,TWF2,CORO1C,CARMIL1,RAC1,DNM2 |
| 3.425e-02 | -3.37 | programmed necrotic cell death | biological process | GO:0097300 | 26 | 8 | 17256 | 2622 |
PPIF,TICAM1,IRF3,CYLD,MAP3K5,BIRC2,FADD,FAS |
| 3.425e-02 | -3.37 | tetrapyrrole biosynthetic process | biological process | GO:0033014 | 26 | 8 | 17256 | 2622 |
COX15,ATP5IF1,MMACHC,CPOX,UROD,TMEM14C,RSAD1,SLC25A39 |
| 3.425e-02 | -3.37 | cleavage involved in rRNA processing | biological process | GO:0000469 | 26 | 8 | 17256 | 2622 |
KRI1,UTP20,EXOSC9,BMS1,EXOSC7,RRS1,RRP36,RPSA |
| 3.425e-02 | -3.37 | positive regulation of mRNA processing | biological process | GO:0050685 | 26 | 8 | 17256 | 2622 |
PAF1,RBMX,TRA2B,THRAP3,SNRNP70,CCNB1,CDC73,PRPF19 |
| 3.429e-02 | -3.37 | GSE22886_NAIVE_CD4_TCELL_VS_12H_ACT_TH2_UP | MSigDB lists | GSE22886_NAIVE_CD4_TCELL_VS_12H_ACT_TH2_UP | 182 | 37 | 17377 | 2626 |
UBL3,PNISR,ZNF768,SF3B1,ANKH,PTP4A3,COX4I1,CHKB,IP6K2,DUSP22,RCOR3,APP,RSAD1,KLHL20,INTS1,ARHGEF1,ZBTB22,TTC3,CDC25B,TTC17,ZNF710,TPCN1,PCBP2,SPSB3,USP34,NIPAL3,CIRBP,SRSF5,STX16,RHOT2,TRAM2,FBXO21,NAP1L1,ATP1A1,ERGIC3,DDX5,TMEM159 |
| 3.429e-02 | -3.37 | GSE26351_WNT_VS_BMP_PATHWAY_STIM_HEMATOPOIETIC_PROGENITORS_UP | MSigDB lists | GSE26351_WNT_VS_BMP_PATHWAY_STIM_HEMATOPOIETIC_PROGENITORS_UP | 182 | 37 | 17377 | 2626 |
GPBP1L1,SEC61G,UQCR10,HNRNPUL2,CENPF,LAGE3,ENSA,SECISBP2,CNTROB,BLM,COMMD5,OAT,PIP4K2A,CNOT3,USP5,KRI1,ERH,RAP1A,ADD3,RINL,PRC1,CDKN1B,CEP63,SPTSSA,SAMD4B,PLK1,KIF15,NARF,POLE,RBL1,E2F4,LIMK1,PSMD8,OGT,LY75,GPI,E2F2 |
| 3.429e-02 | -3.37 | GSE39820_TGFBETA1_VS_TGFBETA3_IN_IL6_IL23A_TREATED_CD4_TCELL_UP | MSigDB lists | GSE39820_TGFBETA1_VS_TGFBETA3_IN_IL6_IL23A_TREATED_CD4_TCELL_UP | 182 | 37 | 17377 | 2626 |
POLA2,RAB14,MUT,IVNS1ABP,URB2,SLC20A1,LYRM2,POLR3K,SPAG5,NDUFS7,BCAT2,PSMD2,NOC2L,RPF2,NDUFB9,CLDND1,GPD1L,PCBP2,PRPF19,DPM1,ACSL3,CKAP2L,PDE3B,MTR,PHF6,EPB41,SUGP1,UTP20,IDE,LUC7L3,EIF2D,PPA2,SCARB1,SMG9,ZBTB11,RTN3,FUBP1 |
| 3.429e-02 | -3.37 | GSE2706_2H_VS_8H_LPS_STIM_DC_UP | MSigDB lists | GSE2706_2H_VS_8H_LPS_STIM_DC_UP | 182 | 37 | 17377 | 2626 |
SLC12A7,MIF4GD,UQCR10,ANKH,CERK,GMCL1,MXD4,CDIPT,SLC12A9,PIP4K2A,CCDC28A,BCAT2,ZNF428,CYB5R1,PRADC1,ERI3,ST8SIA2,GPD1L,TMEM9,IMPA2,EIF3L,EID1,GALC,EMB,BTG2,GNG7,MFNG,ADRB2,RFC2,ARL5B,MAT2A,RHOB,MAN2A2,PON2,PCM1,QARS,ADAM23 |
| 3.429e-02 | -3.37 | GSE3203_INFLUENZA_INF_VS_IFNB_TREATED_LN_BCELL_DN | MSigDB lists | GSE3203_INFLUENZA_INF_VS_IFNB_TREATED_LN_BCELL_DN | 182 | 37 | 17377 | 2626 |
WDR13,ARID5A,MOGS,ARGLU1,POMP,PRPF39,LCLAT1,ANKIB1,CHKA,GOLM1,HOMER1,UBXN2A,GOT2,PPIG,LPIN2,PIK3IP1,ARL5A,S100A6,TACC3,PPAN,ANKLE2,ELOVL5,LAP3,ANKRD33B,EMB,PCGF6,ATXN1,PFKFB3,DCTD,PLEC,RPS9,TMEM201,RPL32,ITGB1,GLG1,USP32,RBMS1 |
| 3.429e-02 | -3.37 | GSE25846_IL10_POS_VS_NEG_CD8_TCELL_DAY7_POST_CORONAVIRUS_BRAIN_DN | MSigDB lists | GSE25846_IL10_POS_VS_NEG_CD8_TCELL_DAY7_POST_CORONAVIRUS_BRAIN_DN | 182 | 37 | 17377 | 2626 |
BCCIP,TOMM20,TM9SF4,FAM53C,CIB1,SLC12A9,DUSP22,PSEN1,MAPK14,HAUS2,FASTKD3,PCNA,TNFAIP8,WDR44,UCHL5,MOB1A,CPSF4,ARL5A,TMED2,SLC25A1,EBAG9,TDP1,TSPYL4,MAN1B1,ATXN1,LRP5,NDUFA7,PRKRA,SERTAD2,TTC13,SPATA2,NIP7,TBL3,ODF2,GPI,WDR91,TUBB |
| 3.429e-02 | -3.37 | GSE21033_CTRL_VS_POLYIC_STIM_DC_6H_UP | MSigDB lists | GSE21033_CTRL_VS_POLYIC_STIM_DC_6H_UP | 182 | 37 | 17377 | 2626 |
UBE2D3,USP7,CHMP2A,ASH1L,ATXN3,TMEM41B,AGFG1,RAPGEF6,MXD1,FBRS,MOAP1,NAPG,MEX3C,PPME1,DCP1A,ANXA5,ECD,ACSL5,ERCC1,PHF10,TMEM39A,GABPA,PFKFB3,TOPORS,AZI2,PICALM,DHX15,RHEB,DERL1,FBXO28,SPATA2,WDR4,FAM3C,USP32,NUMB,SMNDC1,ADNP2 |
| 3.429e-02 | -3.37 | GSE7219_UNSTIM_VS_LPS_AND_ANTI_CD40_STIM_NIK_NFKB2_KO_DC_DN | MSigDB lists | GSE7219_UNSTIM_VS_LPS_AND_ANTI_CD40_STIM_NIK_NFKB2_KO_DC_DN | 182 | 37 | 17377 | 2626 |
ARID5A,TMEM97,DNAJB1,RGS2,IL21R,PPP1R16B,MFSD10,RGS1,MXD1,CREM,APLP2,IRF4,CLIC4,NEK6,LRRC8D,H2AFY,MDFIC,F2R,STAT3,ATP6V0D1,TRIM14,MAPKAPK3,BTG2,KIF15,MKI67,ARHGEF12,LY6E,RHOB,SURF4,ETS2,GADD45B,NFIL3,DTX4,H2AFX,RBPJ,EYA2,CBX4 |
| 3.429e-02 | -3.37 | GSE13306_TREG_VS_TCONV_DN | MSigDB lists | GSE13306_TREG_VS_TCONV_DN | 182 | 37 | 17377 | 2626 |
HSPH1,IMMT,CLSPN,TCF3,ANKH,SECISBP2,IKBIP,PARN,CUTC,KIAA1147,ZNF804A,LYAR,MTMR4,MEA1,CS,AP2B1,YBX1,SLC38A10,DRAM2,CGGBP1,MED22,MND1,EIF3L,PGGT1B,HARS,MRPL12,ADSL,TBRG4,TTC33,MYO1F,YIF1A,SIAH2,FKBP5,RBBP4,TRAF5,ARRB2,POT1 |
| 3.429e-02 | -3.37 | GSE29618_PDC_VS_MDC_UP | MSigDB lists | GSE29618_PDC_VS_MDC_UP | 182 | 37 | 17377 | 2626 |
MAGED1,SMC6,B4GALT1,SLC29A1,ARF1,FKBP2,GGA2,STMN1,SLC20A1,ETS1,APP,PAIP1,CD320,IRF4,RIMS3,UBA5,RRBP1,SEPT11,SCAMP4,LMAN1,SCYL3,SEC61B,MAP4K4,MYBL2,CIRBP,MEF2D,DIDO1,CYFIP2,SOX4,ODC1,SCARB2,CERS6,DCK,OGT,CCDC69,ST3GAL2,USP11 |
| 3.438e-02 | -3.37 | GO_GLYCEROLIPID_BIOSYNTHETIC_PROCESS | MSigDB lists | GO_GLYCEROLIPID_BIOSYNTHETIC_PROCESS | 205 | 41 | 17377 | 2626 |
PIGM,CDS2,PIGN,PIGQ,AGPAT1,AGPAT3,CHKB,ARF1,CDIPT,LCLAT1,PIP4K2A,CPNE3,PIP5K1C,CHKA,FGFR3,PTEN,MTMR4,PIK3R2,SLC44A1,LPIN2,PIGG,PTPN11,PCYT2,PIKFYVE,LPCAT1,GPD1L,CPNE1,PGAP2,PIGT,DPM1,PGS1,PIP4K2C,MTMR6,TAZ,ABHD5,PI4K2A,MTMR3,AGPAT2,LPCAT4,CHPT1,PTDSS1 |
| 3.442e-02 | -3.37 | MID2 (midline 2) | protein interactions | 11043 | 133 | 30 | 17029 | 2761 |
UBE2D3,CDKN2AIP,COX5B,UBE2E2,PPP1R18,ASPM,UBXN1,ELOA,PSMA1,ZFYVE21,GMCL1,GORASP2,BRCA1,RCOR3,SPAG5,UTP25,PSMD2,MID1IP1,GOLGA2,MFAP1,PSMD3,AEN,JOSD1,TRIM32,MVP,IGBP1,TUBB,BYSL,ZNF564,ZBTB24 |
| 3.443e-02 | -3.37 | G2/M DNA replication checkpoint | REACTOME pathways | R-HSA-69478 | 5 | 3 | 10287 | 1696 |
PKMYT1,CCNB1,CCNB2 |
| 3.443e-02 | -3.37 | Activation of RAS in B cells | REACTOME pathways | R-HSA-1169092 | 5 | 3 | 10287 | 1696 |
KRAS,NRAS,HRAS |
| 3.443e-02 | -3.37 | Activation of NOXA and translocation to mitochondria | REACTOME pathways | R-HSA-111448 | 5 | 3 | 10287 | 1696 |
TFDP2,TFDP1,E2F1 |
| 3.443e-02 | -3.37 | GSE40274_CTRL_VS_FOXP3_AND_EOS_TRANSDUCED_ACTIVATED_CD4_TCELL_DN | MSigDB lists | GSE40274_CTRL_VS_FOXP3_AND_EOS_TRANSDUCED_ACTIVATED_CD4_TCELL_DN | 148 | 31 | 17377 | 2626 |
SRM,PLK3,DNAJC2,KARS,GUK1,AACS,TBRG4,TOR1AIP2,DCTD,SLC35B2,RSAD1,EIF3A,PIP5K1C,GTF2F1,HOMER1,GALNT2,HSPA4,SYNCRIP,ETS2,GEMIN6,RPN2,PIEZO1,POLR1B,KLHDC4,RUFY3,CNOT6L,MRPL11,SLC25A39,TMBIM1,IPO4,SLC25A1 |
| 3.443e-02 | -3.37 | GSE8685_IL15_ACT_IL2_STARVED_VS_IL21_ACT_IL2_STARVED_CD4_TCELL_DN | MSigDB lists | GSE8685_IL15_ACT_IL2_STARVED_VS_IL21_ACT_IL2_STARVED_CD4_TCELL_DN | 148 | 31 | 17377 | 2626 |
MLEC,TMEM115,FEZ2,AGGF1,AKT2,RDH10,MFNG,STARD7,LLPH,GALNT7,ADRB2,SNN,SEC16A,LSG1,RPSA,ATPAF1,LRRC14,NSA2,CHCHD3,HERC3,NUP210,TTC13,RPL32,RPS14,APPL2,RPL19,B4GALT3,RRS1,PDLIM5,CBX4,BYSL |
| 3.443e-02 | -3.37 | ATGTTTC,MIR-494 | MSigDB lists | ATGTTTC,MIR-494 | 148 | 31 | 17377 | 2626 |
POU3F2,ZNF207,ELOVL5,ADAM10,C16orf72,RB1CC1,TACC1,PPP1R21,ARHGEF12,NUTF2,GALNT7,EIF1B,API5,DPYSL3,ZNRF2,WDR44,VPS26B,CERS6,LUC7L3,PTER,FUT8,ARNTL,OGT,DMWD,H3F3A,EIF5,SMARCE1,CDK12,CGGBP1,TMED2,PRPF4B |
| 3.450e-02 | -3.37 | chr11q13 | MSigDB lists | chr11q13 | 234 | 46 | 17377 | 2626 |
POLA2,NADSYN1,SART1,ANKRD13D,CDK2AP2,RAB6A,FKBP2,RBM4,SAC3D1,CHKA,FERMT3,SF3B2,RNF121,NDUFV1,KDM2A,PPME1,BANF1,NDUFS8,MRPL48,FAM86C1,MRPL21,MRPL11,CFL1,RNF169,NUDT8,POLR2G,RNASEH2C,DRAP1,TMEM216,LRP5,PACS1,SYVN1,MEN1,MARK2,FADD,CLNS1A,YIF1A,BRMS1,ALDH3B1,PRDX5,ARAP1,PPP6R3,FAU,RTN3,SSSCA1,CAPN1 |
| 3.450e-02 | -3.37 | GO_POSITIVE_REGULATION_OF_INTRACELLULAR_PROTEIN_TRANSPORT | MSigDB lists | GO_POSITIVE_REGULATION_OF_INTRACELLULAR_PROTEIN_TRANSPORT | 234 | 46 | 17377 | 2626 |
DDX58,UBE2D3,ZBED3,CHERP,ZDHHC8,ANK3,CIB1,STARD7,PLAGL2,PPP3CB,PRKACA,MAPK14,BCAP31,CDK5,MDM2,CDC42,HUWE1,PIK3R2,GTSE1,ATG13,MAVS,CYB5R1,HTRA2,PLK3,TGFB1,PPP3CA,RHOA,KAT2A,AKT2,ACSL3,PSMB7,BRCA1,NUTF2,EDEM2,TRIM28,SH3GLB1,USP36,PCM1,KPNA1,PSMD8,OAZ2,PPP3R1,ZNF268,RUFY3,OAZ1,SMAD4 |
| 3.453e-02 | -3.37 | GSE45365_HEALTHY_VS_MCMV_INFECTION_CD11B_DC_IFNAR_KO_DN | MSigDB lists | GSE45365_HEALTHY_VS_MCMV_INFECTION_CD11B_DC_IFNAR_KO_DN | 165 | 34 | 17377 | 2626 |
SEPHS2,RORB,SKA3,HJURP,FOXM1,AGTRAP,CENPF,TKT,CDCA8,HAUS4,KIF2C,NCAPG,MYL6B,SPAG5,CALM2,DTL,OIP5,KIF14,ARF5,RNASEK,NDUFB9,GINS1,MND1,TK1,ASPM,KIF15,MKI67,TOR1AIP2,ANLN,SHCBP1,CDC27,KIF18B,CDCA5,CEP55 |
| 3.453e-02 | -3.37 | GSE6092_IFNG_VS_IFNG_AND_B_BURGDORFERI_INF_ENDOTHELIAL_CELL_DN | MSigDB lists | GSE6092_IFNG_VS_IFNG_AND_B_BURGDORFERI_INF_ENDOTHELIAL_CELL_DN | 165 | 34 | 17377 | 2626 |
PARP12,TMBIM4,AGTRAP,TRIP10,STARD7,PLAGL2,PTP4A3,JMJD6,TBC1D13,REPS1,ANKIB1,CFLAR,CSDE1,RAB21,PSMA6,SAR1A,KLF16,TANK,ETV6,PTPN11,TRA2B,MVP,ACSL5,NCK1,PGS1,COQ10B,AMD1,ZFAND5,TRAM2,SIAH2,CHMP4B,TCOF1,RNF14,PFKP |
| 3.463e-02 | -3.36 | tRNA modification in the nucleus and cytosol | REACTOME pathways | R-HSA-6782315 | 42 | 12 | 10287 | 1696 |
METTL1,CTU2,EPRS,TP53RK,TRMT6,TYW1,WDR4,NSUN2,TYW5,FTSJ1,LAGE3,DUS2 |
| 3.465e-02 | -3.36 | POP4 (POP4 homolog, ribonuclease P/MRP subunit) | protein interactions | 10775 | 38 | 11 | 17029 | 2761 |
RPP25,PPP1R9B,PRKCSH,POP7,AMD1,CBWD1,TOR1AIP2,PRPF4,OSTF1,RBM4,IFI16 |
| 3.465e-02 | -3.36 | PIP4K2C (phosphatidylinositol-5-phosphate 4-kinase type 2 gamma) | protein interactions | 79837 | 38 | 11 | 17029 | 2761 |
ZNF428,GPBP1L1,TULP3,GSPT2,PIP4K2C,CSNK2A1,ZRANB2,MTPN,PIP4K2A,APP,DDX23 |
| 3.465e-02 | -3.36 | HDGFL2 (HDGF like 2) | protein interactions | 84717 | 38 | 11 | 17029 | 2761 |
IER2,EWSR1,KLHL20,DBF4,CSNK2A1,XRCC3,ARRB2,PARK7,PIP4K2A,TERF1,TERF2 |
| 3.465e-02 | -3.36 | KAT6A (lysine acetyltransferase 6A) | protein interactions | 7994 | 38 | 11 | 17029 | 2761 |
HSPA4,MAFK,PHF14,PML,RNPS1,ATXN1,PNPLA8,CCNB1,WDR5,SYMPK,MEAF6 |
| 3.465e-02 | -3.36 | UPF3A (UPF3A, regulator of nonsense mediated mRNA decay) | protein interactions | 65110 | 38 | 11 | 17029 | 2761 |
FGFR1OP,UPF1,AGGF1,PIGT,RBM8A,RNPS1,TOPORS,UPF2,FUS,PARN,APP |
| 3.465e-02 | -3.36 | GNPDA1 (glucosamine-6-phosphate deaminase 1) | protein interactions | 10007 | 38 | 11 | 17029 | 2761 |
SEC31A,PCNA,EWSR1,GNPDA1,EZR,STK11,AMDHD2,PSMD9,PABPC1,RAD23A,USP5 |
| 3.465e-02 | -3.36 | APBA3 (amyloid beta precursor protein binding family A member 3) | protein interactions | 9546 | 38 | 11 | 17029 | 2761 |
APLP2,PKP4,ZKSCAN1,TANK,PIP4K2C,CTR9,DUSP11,AZI2,GFER,APP,RAPGEF6 |
| 3.465e-02 | -3.36 | Csnk1e (casein kinase 1, epsilon) | protein interactions | 27373 | 38 | 11 | 17029 | 2761 |
EIF5A,AHNAK,FAM110A,NACA,TKT,CRY2,TAGLN2,GPI,PKM,PCBP1,VPS13B |
| 3.465e-02 | -3.36 | ESPL1 (extra spindle pole bodies like 1, separase) | protein interactions | 9700 | 38 | 11 | 17029 | 2761 |
PPP2CA,CDC16,PPP2R5A,PTTG1,FBXO7,IARS2,RFFL,KIF2C,CCNB1,USP11,USP21 |
| 3.465e-02 | -3.36 | ACSL3 (acyl-CoA synthetase long chain family member 3) | protein interactions | 2181 | 38 | 11 | 17029 | 2761 |
STAU1,CYLD,TMEM216,PPP6R2,MCM2,LYN,KIF11,REEP5,PPP6R1,APP,EVC2 |
| 3.465e-02 | -3.36 | BTBD2 (BTB domain containing 2) | protein interactions | 55643 | 38 | 11 | 17029 | 2761 |
COPS8,C9orf78,SMAD2,UBXN1,CUL3,BRD7,KPNA2,COPS6,SMAD1,CDK2,BTBD1 |
| 3.465e-02 | -3.36 | RPF1 (ribosome production factor 1 homolog) | protein interactions | 80135 | 38 | 11 | 17029 | 2761 |
NOL12,NIFK,UPF1,ZNF512,ZNF689,RPF2,KRAS,ZBTB11,MAK16,ZC3H3,IFI16 |
| 3.465e-02 | -3.36 | CNOT3 (CCR4-NOT transcription complex subunit 3) | protein interactions | 4849 | 38 | 11 | 17029 | 2761 |
CNOT9,MEX3C,GADD45B,CIRBP,CNOT6,CAPZA2,CNTROB,CNOT6L,CNOT11,TOB1,CAND1 |
| 3.465e-02 | -3.36 | GOLGB1 (golgin B1) | protein interactions | 2804 | 38 | 11 | 17029 | 2761 |
BRMS1,CCDC93,USP7,USO1,EWSR1,TMED10,DYNLL1,UBE2I,ECPAS,TMED2,CDC5L |
| 3.465e-02 | -3.36 | IMPA2 (inositol monophosphatase 2) | protein interactions | 3613 | 38 | 11 | 17029 | 2761 |
ADSS,TXN,PDCD6,DUT,CYCS,GLO1,STMN1,PARK7,PABPC4,IMPA2,GPX4 |
| 3.468e-02 | -3.36 | proton-transporting ATP synthase complex | cellular component | GO:0045259 | 22 | 7 | 18223 | 2701 |
PPIF,ATP5IF1,ATP5F1A,ATP5F1B,ATP5MF,ATP5PF,ATP5MC3 |
| 3.473e-02 | -3.36 | GO_POSITIVE_REGULATION_OF_CHROMATIN_MODIFICATION | MSigDB lists | GO_POSITIVE_REGULATION_OF_CHROMATIN_MODIFICATION | 82 | 19 | 17377 | 2626 |
TGFB1,KAT2A,MIER1,WBP2,RTF1,BRCA1,CCNB1,TRIM28,MAPK3,PAF1,AKAP8,OGT,PML,BRD7,CTR9,RUVBL2,CHTOP,DNMT1,SMAD4 |
| 3.474e-02 | -3.36 | BYSTRYKH_HEMATOPOIESIS_STEM_CELL_FLI1 | MSigDB lists | BYSTRYKH_HEMATOPOIESIS_STEM_CELL_FLI1 | 9 | 4 | 17377 | 2626 |
TAP2,RAB5B,IFT27,DBF4 |
| 3.474e-02 | -3.36 | SA_FAS_SIGNALING | MSigDB lists | SA_FAS_SIGNALING | 9 | 4 | 17377 | 2626 |
BCL2,CFL1,CFLAR,FAS |
| 3.474e-02 | -3.36 | IIZUKA_LIVER_CANCER_PROGRESSION_G2_G3_DN | MSigDB lists | IIZUKA_LIVER_CANCER_PROGRESSION_G2_G3_DN | 9 | 4 | 17377 | 2626 |
TGFB1,DAZAP2,BAZ2A,PPT1 |
| 3.474e-02 | -3.36 | KONG_E2F1_TARGETS | MSigDB lists | KONG_E2F1_TARGETS | 9 | 4 | 17377 | 2626 |
NUSAP1,KPNA1,E2F1,H2AFX |
| 3.474e-02 | -3.36 | CHEN_HOXA5_TARGETS_6HR_UP | MSigDB lists | CHEN_HOXA5_TARGETS_6HR_UP | 9 | 4 | 17377 | 2626 |
IER2,KLF10,TIPARP,GADD45B |
| 3.474e-02 | -3.36 | GO_AMINOACYL_TRNA_EDITING_ACTIVITY | MSigDB lists | GO_AMINOACYL_TRNA_EDITING_ACTIVITY | 9 | 4 | 17377 | 2626 |
DTD1,LARS,IARS,IARS2 |
| 3.474e-02 | -3.36 | OHASHI_AURKB_TARGETS | MSigDB lists | OHASHI_AURKB_TARGETS | 9 | 4 | 17377 | 2626 |
RACGAP1,KIF2C,AURKB,CDCA8 |
| 3.474e-02 | -3.36 | REACTOME_COPI_MEDIATED_TRANSPORT | MSigDB lists | REACTOME_COPI_MEDIATED_TRANSPORT | 9 | 4 | 17377 | 2626 |
ARF1,COPA,COPB2,COPE |
| 3.474e-02 | -3.36 | GO_HISTONE_H4_K5_ACETYLATION | MSigDB lists | GO_HISTONE_H4_K5_ACETYLATION | 9 | 4 | 17377 | 2626 |
WDR5,KAT7,MEAF6,OGT |
| 3.474e-02 | -3.36 | GO_HISTONE_H4_K8_ACETYLATION | MSigDB lists | GO_HISTONE_H4_K8_ACETYLATION | 9 | 4 | 17377 | 2626 |
WDR5,KAT7,MEAF6,OGT |
| 3.475e-02 | -3.36 | Endosomal/Vacuolar pathway | REACTOME pathways | R-HSA-1236977 | 12 | 5 | 10287 | 1696 |
CTSL,HLA-B,CTSS,HLA-E,HLA-A |
| 3.475e-02 | -3.36 | Purine ribonucleoside monophosphate biosynthesis | REACTOME pathways | R-HSA-73817 | 12 | 5 | 10287 | 1696 |
ADSS,ADSL,IMPDH1,GART,ATIC |
| 3.475e-02 | -3.36 | Josephin domain DUBs | REACTOME pathways | R-HSA-5689877 | 12 | 5 | 10287 | 1696 |
JOSD1,ATXN3,RPS27A,RAD23B,RAD23A |
| 3.481e-02 | -3.36 | ATN1 (atrophin 1) | protein interactions | 1822 | 102 | 24 | 17029 | 2761 |
PDCD6IP,EWSR1,AGRN,PRRC2A,KAT7,MAP7D1,SYVN1,CBFA2T2,WDR5,GIGYF1,SPAG5,WWP2,CACNB1,LTBP4,SIAH1,CENPJ,MEGF8,SIAH2,NOC2L,DVL1,TERF1,GCC1,DVL2,TERF2 |
| 3.482e-02 | -3.36 | superpathway of guanosine nucleotides de novo biosynthesis I | BIOCYC pathways | META_PWY-7228 | 8 | 4 | 902 | 157 |
IMPDH1,RRM2,GUK1,RRM1 |
| 3.486e-02 | -3.36 | superpathway of conversion of glucose to acetyl CoA and entry into the TCA cycle | BIOCYC pathways | HUMAN_PWY66-407 | 36 | 11 | 902 | 157 |
SDHB,SUCLG1,IDH3A,MDH2,CS,SUCLG2,MDH1,OGDH,PKM,SDHA,PFKP |
| 3.487e-02 | -3.36 | Cyclin-like_sf | interpro domains | IPR036915 | 41 | 11 | 18492 | 2768 |
CCNC,CCNK,RB1,CCNA2,RBL1,CCNL2,CABLES2,CCNB1,CCNF,CCNB2,CABLES1 |
| 3.491e-02 | -3.36 | NLK (nemo like kinase) | protein interactions | 51701 | 57 | 15 | 17029 | 2761 |
MDM2,CCP110,TAB2,HIPK2,MYBL2,CUL1,ATXN1,RANGAP1,PKM,MYBL1,STAT3,CNOT11,FOXO3,SMAD4,CNOT3 |
| 3.491e-02 | -3.36 | MKRN3 (makorin ring finger protein 3) | protein interactions | 7681 | 57 | 15 | 17029 | 2761 |
UBE2D3,ERCC1,UBE2E2,MDM2,TRIM8,PEX5,FAM110A,NABP1,PSMA1,UBE2V1,UBE2I,NDE1,LRSAM1,NKAPD1,TRIM65 |
| 3.491e-02 | -3.36 | PPID (peptidylprolyl isomerase D) | protein interactions | 5481 | 57 | 15 | 17029 | 2761 |
PLK1,UNK,KAT7,AHSA1,UROD,AEN,BCL2,DNAJB1,PTGES3,PKM,OAT,APP,S100A6,TUBB,CDC37 |
| 3.491e-02 | -3.36 | PCGF2 (polycomb group ring finger 2) | protein interactions | 7703 | 57 | 15 | 17029 | 2761 |
PHC2,UBE2D3,USP7,UBE2E2,UBE2Q2,VHL,GOPC,RANGAP1,YY1,UBE2I,USP11,PCBP1,CBX4,LMNA,RYBP |
| 3.498e-02 | -3.35 | negative regulation of neuron death | biological process | GO:1901215 | 187 | 38 | 17256 | 2622 |
GCLM,DNAJC5,MECP2,BCL2L1,PSEN1,PARK7,CDK5,TIGAR,PIN1,KIF14,FBXO7,XRCC2,MSH2,AP2B1,BCL2,CORO1A,CREB1,F2R,STAT3,HTRA2,PDPK1,RHOA,PPT1,BTG2,OXR1,GBA,KRAS,TSC1,CHMP4A,HIPK2,CHMP4B,ROCK1,PPP5C,BTBD10,CLN3,ARRB2,PSMC1,HRAS |
| 3.499e-02 | -3.35 | GSE29949_CD8_NEG_DC_SPLEEN_VS_DC_BRAIN_DN | MSigDB lists | GSE29949_CD8_NEG_DC_SPLEEN_VS_DC_BRAIN_DN | 188 | 38 | 17377 | 2626 |
SEPHS2,FGFR1OP,NDUFB6,PTTG1,MED13L,B4GALT4,RLF,GGPS1,SPAG5,PAPOLA,RB1,EIF2S2,EIF4A3,PDS5B,AP2B1,MDFIC,GEMIN4,PRPF19,POU2AF1,MIOS,ZNF84,FAM172A,PPIE,ITM2A,EXOSC9,PDE3B,PI4K2A,ADSS,TAF2,KPNA1,PRDX3,ACOX1,UBXN2B,ACAT1,TRIM32,XRCC4,CSNK1D,DDX52 |
| 3.499e-02 | -3.35 | GSE12198_CTRL_VS_HIGH_IL2_STIM_NK_CELL_DN | MSigDB lists | GSE12198_CTRL_VS_HIGH_IL2_STIM_NK_CELL_DN | 188 | 38 | 17377 | 2626 |
SRM,RHOG,IER2,ZCCHC9,TMEM184B,HNRNPAB,TM9SF4,TRIP10,MOGS,FAM76A,B4GALT1,MYH9,GTF3A,SIRT2,NOTCH2,MAPK14,MLX,HDAC7,ARHGEF2,ORAI1,MOB1A,UBE2M,MGAT5,PDLIM2,TK1,TIMP2,LDB1,ODC1,MAK16,NMT2,USP36,OSBPL11,PDLIM1,CCDC86,SETD3,RBMX,MRPL27,ACLY |
| 3.499e-02 | -3.35 | GSE3982_DC_VS_NEUTROPHIL_LPS_STIM_DN | MSigDB lists | GSE3982_DC_VS_NEUTROPHIL_LPS_STIM_DN | 188 | 38 | 17377 | 2626 |
FGFR1OP,HECA,GPR132,GGNBP2,COPA,DCAF15,KLHL21,WDTC1,FLOT1,CHIC2,JMJD6,PAWR,RGS2,ETS1,HAUS2,TERF2IP,CDC42,CD3EAP,ZNF639,TFG,RHOA,TNFAIP3,BTG2,KCTD20,USP10,EMP3,MCL1,AMDHD2,PRMT2,ZNF407,EIF4H,DAPK3,MYO1F,NEIL3,OAZ2,PPP1R11,H3F3A,CSNK1D |
| 3.499e-02 | -3.35 | GSE11961_MEMORY_BCELL_DAY7_VS_MEMORY_BCELL_DAY40_DN | MSigDB lists | GSE11961_MEMORY_BCELL_DAY7_VS_MEMORY_BCELL_DAY40_DN | 188 | 38 | 17377 | 2626 |
BCCIP,UBE2E2,CASP6,MXD4,EIF2AK4,GGA2,PRKACA,EEF2K,TNFAIP8,GMEB1,GM2A,CAMK2G,TTPAL,ORAI2,USO1,HPDL,LACTB,EMP3,MAP7D1,MEF2D,PLEC,PTTG1IP,KLF6,DHX57,MAPK3,DDX17,CAT,ZNF317,HNRNPR,RBMX,CAMKMT,HAGHL,MEGF9,ACADM,ZSWIM3,BRD9,ARRB2,POT1 |
| 3.499e-02 | -3.35 | GSE20366_TREG_VS_NAIVE_CD4_TCELL_HOMEOSTATIC_CONVERSION_UP | MSigDB lists | GSE20366_TREG_VS_NAIVE_CD4_TCELL_HOMEOSTATIC_CONVERSION_UP | 188 | 38 | 17377 | 2626 |
MIF,GALK1,MIF4GD,H2AFZ,HNRNPAB,CLSPN,RWDD1,FAM129A,SRGN,VAV2,PTP4A3,CNTROB,LCLAT1,REEP5,MAN1A1,PRNP,ATP2A2,RCSD1,TP53BP2,ARL5A,PPA1,N4BP2,GM2A,S100A6,MLST8,HEMK1,MKLN1,KRAS,RBM38,ADSS,HINT1,HIPK2,TPP2,FAM83D,YWHAZ,KPNA2,FAF1,FAM72A |
| 3.499e-02 | -3.35 | GSE23502_WT_VS_HDC_KO_MYELOID_DERIVED_SUPPRESSOR_CELL_BM_DN | MSigDB lists | GSE23502_WT_VS_HDC_KO_MYELOID_DERIVED_SUPPRESSOR_CELL_BM_DN | 188 | 38 | 17377 | 2626 |
CYTIP,SLC41A1,MDH2,TRIO,FLOT1,B4GALT1,NIPA2,HMGN3,ADPGK,RAB6A,CHD1,SLC31A1,SUB1,RAP1A,EIF2S2,VMP1,IL6ST,BCAP29,PIK3IP1,TIPARP,PPA1,POU2AF1,COQ10B,ANKRD33B,PGS1,RNPS1,ATXN1,PFKFB3,TTC33,PRDX1,MAN2A2,RBM47,DUSP3,SNAP23,STK38,NFIL3,ATF6,HIPK3 |
| 3.503e-02 | -3.35 | lung-carcinoid-endocrine_tumour | COSMIC cancer mutations | lung-carcinoid-endocrine_tumour | 504 | 90 | 17385 | 2587 |
MAX,TP53RK,PNISR,SF3B1,RPS6KA1,RAF1,COPE,CSNK2A1,SMARCA4,PRKACA,TWF2,LYN,MAPK14,EEF2K,CDK5,ABL2,PDK2,PRKD3,NEK6,MTMR4,IL6ST,SCYL3,CDK12,SRPK2,PLK1,PLK3,NRAS,BRD4,AKT2,VHL,PBK,TLK1,MAP4K4,PKMYT1,AURKB,EML4,STK17B,TRIM28,MAP3K4,JAK1,CLK3,SPATA2,STK38,HIPK2,FASTK,LIMK1,STK11,RNASEL,CHEK2,MAPK1,PRPF4B,SCYL1,TRIO,TCF3,PRKAA1,CDK13,SECISBP2,ADCK5,EIF2AK4,CSNK1A1,SCYL2,FGFR3,PTEN,DAPK1,ZRANB1,PHKG2,SYTL3,CAMK2G,CSNK1G3,PDPK1,CSNK1G2,NEK7,EIF2AK1,MAP4K3,KRAS,MEN1,MARK2,MAP2K2,DAPK3,MAPK3,MASTL,MAPK6,TYW5,DDX5,MAP3K5,CDK2,RPS6KC1,HIPK3,HRAS,NRBP1 |
| 3.504e-02 | -3.35 | adrenal_gland-adrenal_gland-pheochromocytoma-benign | COSMIC cancer mutations | adrenal_gland-adrenal_gland-pheochromocytoma-benign | 226 | 44 | 17385 | 2587 |
MAX,PNISR,NPHP4,ZCCHC8,NF1,MRPL39,ANK3,SMARCA4,ZNF107,EIF2AK4,ZADH2,FAM8A1,GNB2,NUP205,RAD23B,DCP1A,CTR9,NAP1L4,APOOL,ZRANB1,STAT3,RNLS,ZNF189,PTPRK,CNTN5,NRAS,SEPT9,PPT1,VHL,KRAS,CAPZA2,MPG,ZNF407,AHNAK,FNTA,PALB2,CTSA,WIPI2,AKNA,ZNF598,ABCA1,HRAS,TERF1,PFKP |
| 3.507e-02 | -3.35 | Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components | REACTOME pathways | R-HSA-141405 | 20 | 7 | 10287 | 1696 |
ANAPC2,ANAPC7,CDC16,CDC23,CDC27,UBE2C,ANAPC4 |
| 3.507e-02 | -3.35 | Inactivation of APC/C via direct inhibition of the APC/C complex | REACTOME pathways | R-HSA-141430 | 20 | 7 | 10287 | 1696 |
ANAPC2,ANAPC7,CDC16,CDC23,CDC27,UBE2C,ANAPC4 |
| 3.511e-02 | -3.35 | REACTOME_SPRY_REGULATION_OF_FGF_SIGNALING | MSigDB lists | REACTOME_SPRY_REGULATION_OF_FGF_SIGNALING | 13 | 5 | 17377 | 2626 |
PPP2CA,MKNK1,MAPK1,RPS27A,MAPK3 |
| 3.511e-02 | -3.35 | VETTER_TARGETS_OF_PRKCA_AND_ETS1_DN | MSigDB lists | VETTER_TARGETS_OF_PRKCA_AND_ETS1_DN | 13 | 5 | 17377 | 2626 |
ARHGDIB,MRPL9,SP100,NQO1,CCDC28A |
| 3.511e-02 | -3.35 | GO_RRNA_3_END_PROCESSING | MSigDB lists | GO_RRNA_3_END_PROCESSING | 13 | 5 | 17377 | 2626 |
EXOSC9,EXOSC6,EXOSC7,ERI3,RPSA |
| 3.511e-02 | -3.35 | GO_HEXOSAMINIDASE_ACTIVITY | MSigDB lists | GO_HEXOSAMINIDASE_ACTIVITY | 13 | 5 | 17377 | 2626 |
NAGPA,HEXA,GM2A,NAGLU,HEXB |
| 3.511e-02 | -3.35 | WU_HBX_TARGETS_1_UP | MSigDB lists | WU_HBX_TARGETS_1_UP | 13 | 5 | 17377 | 2626 |
HMGB2,ACP2,SLC25A5,UCK2,FAS |
| 3.511e-02 | -3.35 | GO_NEGATIVE_REGULATION_OF_ESTABLISHMENT_OF_PROTEIN_LOCALIZATION_TO_PLASMA_MEMBRANE | MSigDB lists | GO_NEGATIVE_REGULATION_OF_ESTABLISHMENT_OF_PROTEIN_LOCALIZATION_TO_PLASMA_MEMBRANE | 13 | 5 | 17377 | 2626 |
BCL2L1,PPP2R5A,CSK,GOPC,TMBIM1 |
| 3.511e-02 | -3.35 | GO_MATURATION_OF_LSU_RRNA | MSigDB lists | GO_MATURATION_OF_LSU_RRNA | 13 | 5 | 17377 | 2626 |
NSA2,RPF2,RPL35,MAK16,FTSJ3 |
| 3.511e-02 | -3.35 | MODULE_150 | MSigDB lists | MODULE_150 | 13 | 5 | 17377 | 2626 |
RPLP2,EEF1D,EFTUD2,RPLP1,TUFM |
| 3.511e-02 | -3.35 | GO_PERICENTRIC_HETEROCHROMATIN | MSigDB lists | GO_PERICENTRIC_HETEROCHROMATIN | 13 | 5 | 17377 | 2626 |
H2AFY,BAZ1B,KDM4A,DNMT1,CBX3 |
| 3.511e-02 | -3.35 | BIOCARTA_RB_PATHWAY | MSigDB lists | BIOCARTA_RB_PATHWAY | 13 | 5 | 17377 | 2626 |
RB1,CDC25B,MAPK14,CDK2,YWHAH |
| 3.511e-02 | -3.35 | BIOCARTA_SALMONELLA_PATHWAY | MSigDB lists | BIOCARTA_SALMONELLA_PATHWAY | 13 | 5 | 17377 | 2626 |
CDC42,ARPC1A,ARPC5,ACTR3,RAC1 |
| 3.511e-02 | -3.35 | GO_CONDENSED_NUCLEAR_CHROMOSOME_CENTROMERIC_REGION | MSigDB lists | GO_CONDENSED_NUCLEAR_CHROMOSOME_CENTROMERIC_REGION | 13 | 5 | 17377 | 2626 |
PLK1,SS18L1,AURKB,CCNB1,MIS12 |
| 3.511e-02 | -3.35 | GO_NUCLEOSIDE_KINASE_ACTIVITY | MSigDB lists | GO_NUCLEOSIDE_KINASE_ACTIVITY | 13 | 5 | 17377 | 2626 |
UCK1,UPRT,TK1,DCK,UCK2 |
| 3.511e-02 | -3.35 | GO_POSITIVE_REGULATION_OF_MRNA_SPLICING_VIA_SPLICEOSOME | MSigDB lists | GO_POSITIVE_REGULATION_OF_MRNA_SPLICING_VIA_SPLICEOSOME | 13 | 5 | 17377 | 2626 |
TRA2B,THRAP3,SNRNP70,RBMX,PRPF19 |
| 3.511e-02 | -3.35 | GO_UBIQUITIN_UBIQUITIN_LIGASE_ACTIVITY | MSigDB lists | GO_UBIQUITIN_UBIQUITIN_LIGASE_ACTIVITY | 13 | 5 | 17377 | 2626 |
UBE4B,UBE4A,RBX1,PPIL2,PRPF19 |
| 3.511e-02 | -3.35 | GO_S100_PROTEIN_BINDING | MSigDB lists | GO_S100_PROTEIN_BINDING | 13 | 5 | 17377 | 2626 |
EZR,AHNAK,ATP2A2,S100A6,ANXA11 |
| 3.511e-02 | -3.35 | GO_HISTONE_METHYLTRANSFERASE_ACTIVITY_H3_K4_SPECIFIC_ | MSigDB lists | GO_HISTONE_METHYLTRANSFERASE_ACTIVITY_H3_K4_SPECIFIC_ | 13 | 5 | 17377 | 2626 |
WDR82,ASH1L,WDR5,SETD3,CXXC1 |
| 3.511e-02 | -3.35 | BIOCARTA_ARENRF2_PATHWAY | MSigDB lists | BIOCARTA_ARENRF2_PATHWAY | 13 | 5 | 17377 | 2626 |
KEAP1,CREB1,MAPK1,MAPK14,MAFK |
| 3.511e-02 | -3.35 | MODULE_465 | MSigDB lists | MODULE_465 | 13 | 5 | 17377 | 2626 |
BAZ1B,SLC27A4,GTF2H2,PDE3B,SRXN1 |
| 3.511e-02 | -3.35 | GO_MAGNESIUM_ION_TRANSPORT | MSigDB lists | GO_MAGNESIUM_ION_TRANSPORT | 13 | 5 | 17377 | 2626 |
NIPAL3,NIPA2,MAGT1,NIPA1,MRS2 |
| 3.511e-02 | -3.35 | GO_CCR4_NOT_COMPLEX | MSigDB lists | GO_CCR4_NOT_COMPLEX | 13 | 5 | 17377 | 2626 |
CNOT6,CNOT6L,PATL1,TOB1,CNOT3 |
| 3.511e-02 | -3.35 | GO_PROTEIN_DEMANNOSYLATION | MSigDB lists | GO_PROTEIN_DEMANNOSYLATION | 13 | 5 | 17377 | 2626 |
SYVN1,EDEM2,MAN1B1,MAN1A1,SEL1L |
| 3.511e-02 | -3.35 | GO_PROTEIN_ALPHA_1_2_DEMANNOSYLATION | MSigDB lists | GO_PROTEIN_ALPHA_1_2_DEMANNOSYLATION | 13 | 5 | 17377 | 2626 |
SYVN1,EDEM2,MAN1B1,MAN1A1,SEL1L |
| 3.511e-02 | -3.35 | GO_MITOCHONDRIAL_ELECTRON_TRANSPORT_UBIQUINOL_TO_CYTOCHROME_C | MSigDB lists | GO_MITOCHONDRIAL_ELECTRON_TRANSPORT_UBIQUINOL_TO_CYTOCHROME_C | 13 | 5 | 17377 | 2626 |
UQCRH,CYCS,CYC1,UQCR10,MECP2 |
| 3.511e-02 | -3.35 | REACTOME_N_GLYCAN_TRIMMING_IN_THE_ER_AND_CALNEXIN_CALRETICULIN_CYCLE | MSigDB lists | REACTOME_N_GLYCAN_TRIMMING_IN_THE_ER_AND_CALNEXIN_CALRETICULIN_CYCLE | 13 | 5 | 17377 | 2626 |
MLEC,EDEM2,PRKCSH,MAN1B1,MOGS |
| 3.511e-02 | -3.35 | SCHWAB_TARGETS_OF_BMYB_POLYMORPHIC_VARIANTS_UP | MSigDB lists | SCHWAB_TARGETS_OF_BMYB_POLYMORPHIC_VARIANTS_UP | 13 | 5 | 17377 | 2626 |
CDKN2C,NFATC3,MDM2,RHOT2,CENPF |
| 3.511e-02 | -3.35 | MODULE_25 | MSigDB lists | MODULE_25 | 13 | 5 | 17377 | 2626 |
NDUFV2,NDUFS8,NDUFV1,NDUFS5,NDUFS4 |
| 3.511e-02 | -3.35 | GO_RNA_SURVEILLANCE | MSigDB lists | GO_RNA_SURVEILLANCE | 13 | 5 | 17377 | 2626 |
EXOSC9,EXOSC6,EXOSC7,PRPF18,PELO |
| 3.511e-02 | -3.35 | GO_PROTEIN_IMPORT_INTO_MITOCHONDRIAL_MATRIX | MSigDB lists | GO_PROTEIN_IMPORT_INTO_MITOCHONDRIAL_MATRIX | 13 | 5 | 17377 | 2626 |
TOMM20,TOMM40,TIMM23,TIMM17A,TIMM50 |
| 3.511e-02 | -3.35 | GO_ENDOPLASMIC_RETICULUM_QUALITY_CONTROL_COMPARTMENT | MSigDB lists | GO_ENDOPLASMIC_RETICULUM_QUALITY_CONTROL_COMPARTMENT | 13 | 5 | 17377 | 2626 |
SYVN1,EDEM2,RHBDD1,MAN1B1,SEL1L |
| 3.511e-02 | -3.35 | GO_POSITIVE_REGULATION_OF_ERAD_PATHWAY | MSigDB lists | GO_POSITIVE_REGULATION_OF_ERAD_PATHWAY | 13 | 5 | 17377 | 2626 |
ATXN3,UBQLN2,EDEM2,BCAP31,USP13 |
| 3.512e-02 | -3.35 | GAGCCAG,MIR-149 | MSigDB lists | GAGCCAG,MIR-149 | 137 | 29 | 17377 | 2626 |
TCF12,MLEC,ADD1,KAT7,BTG2,USP10,CTCF,CREBL2,CHKB,ARID1A,SRSF5,NCDN,CD59,TFAP4,RAP1A,SERF2,BRPF3,ATP2A2,CCDC6,LUC7L3,SEC24C,PRPS2,ZNF335,LPCAT4,ACLY,CLCN6,APPL2,KHSRP,YWHAZ |
| 3.512e-02 | -3.35 | KEGG_INSULIN_SIGNALING_PATHWAY | MSigDB lists | KEGG_INSULIN_SIGNALING_PATHWAY | 137 | 29 | 17377 | 2626 |
PDPK1,PRKAB1,NRAS,TSC2,TRIP10,AKT2,RAF1,PRKAA1,PRKAR1B,FLOT1,KRAS,ELK1,PDE3B,PRKACA,MAP2K2,RHEB,MAPK3,CRKL,PPP1R3B,CALM2,PTPRF,TSC1,MKNK1,SHC1,PIK3R2,SOCS4,MAPK1,PHKG2,HRAS |
| 3.515e-02 | -3.35 | small_cell_carcinoma | COSMIC cancer mutations | small_cell_carcinoma | 10152 | 1553 | 17385 | 2587 |
ZBTB10,TSC2,ABCC10,LACTB2,CCNL2,RBM4,ZNF275,FBXO22,EEF2K,CDKN2C,USF1,RAD23B,ATP13A3,AP1M1,DNM2,UPRT,CRY2,RNF26,TIPARP,MGAT5,USP34,BAK1,CCDC57,ERCC1,ZNF559,RHOBTB3,NRAS,GABPA,EHMT1,KIF15,HNRNPF,WDHD1,MIER2,DIDO1,MCM2,RAB22A,ARF4,KRIT1,AHNAK,SMAD2,MID1IP1,RAD18,OGT,RNASEL,SMAD1,SMNDC1,PDCD4,SLC25A33,NXT2,HIVEP3,CLSPN,KIAA0100,SEC61G,RHOC,MUM1,TRIO,DHX9,RAB23,EIF2AK4,PDCD7,APH1B,CDC73,ATG4A,TMEM179B,TFAP4,ERV3-1,PDXP,C4orf3,RNFT1,RIMS3,MEGF8,FBXO7,EFTUD2,GEMIN4,MRPL21,MVP,NUP85,PABPC1,PHKG2,LUC7L2,SRSF11,AGGF1,FOXK1,RBM42,GTPBP4,ITM2A,USP10,BCLAF1,ELK1,EIF4H,MAGED2,KPNA1,TXNDC16,ETS2,WIPI2,MRPL3,ALS2,EXOC3,RHOG,KARS,TRIM41,PTTG1,ANK3,C5orf30,TPX2,LCLAT1,RCOR3,REPS1,RBM23,FBXL6,ZNF420,AHCTF1,MTA1,UBA5,GMEB1,NSFL1C,CLCN6,INTS12,ZC3H3,RPRD1B,ARL5A,CGGBP1,SNX8,ERMP1,GOPC,IDH3A,CRNKL1,CIRBP,E2F3,PFKFB3,GORAB,MEF2D,TANC1,RAB1A,GIGYF1,TMEM184C,KIF2A,PPP2CA,LSM6,CORO1C,NSMCE2,CAMKMT,RNF38,CENPBD1,PPP5C,USP13,ZNF445,SRSF6,CCM2,FLOT1,BTN3A1,ATG2B,IP6K2,WDR5,PMVK,IFT27,SLC25A43,NEIL2,PPP1R3B,RPA2,PSMD2,PDCD10,CLIC4,ITGB8,HUWE1,ARF5,ARHGEF1,ANXA5,LTN1,UBE3B,NAP1L4,ST8SIA2,FBXL19,GTF2H2,SPTAN1,STAU1,DDX24,TACC1,MRS2,LDHA,HEBP2,RAB3IP,PICALM,UTP20,MAGT1,FAM3C,DBI,AEN,CD81,PARP10,YWHAH,TMEM131,WDR13,TRIM11,FAM129A,SNX15,RUFY1,TRIM65,FANCI,PAPOLA,ZER1,PRNP,FANCL,RAB8A,NUP210,NT5DC1,INTS1,IL6ST,SLC44A1,MTPN,ASB6,TACC3,VPS13B,PLK1,PTPN18,SEPT9,CELSR2,RBX1,APH1A,SNRPB,RAD51AP1,CKAP2L,CDC6,UBE2V1,UTP3,PBRM1,USP21,TRIM4,FBXO28,CHD3,E2F4,BCL7C,ADAM9,KPNA2,DVL1,CLN3,FAM208A,NGLY1,POT1,NUMB,CCDC137,FUBP1,RMND5A,PARP12,HJURP,FAM53C,DNAJB2,CENPF,NKD2,LAMTOR3,COX4I1,ADCK5,CDK13,RAB6A,DNAJB1,NCKAP1,ARID1B,TNS3,C1GALT1,CCP110,KIF13B,MBD2,ZNF746,XPA,ARL6IP1,CTR9,RBM3,GLE1,LRSAM1,HDHD2,ABHD2,DCAF8,NSDHL,ACSL3,LDB1,CAMSAP1,MAP4K3,METTL22,ICAM2,ARMC8,STYXL1,IRF5,NMT2,HAUS8,RXRB,SDHB,MBIP,PCM1,GALNT2,TMEM168,ORMDL2,COX7A2L,NLRC5,ZDHHC7,SIL1,RUVBL2,BTBD10,MYO9A,CCNB2,UNC13C,USP7,SART1,TRAF7,ARID2,TMX4,TOR1AIP1,LAGE3,ATP6V1B2,PCBP1,LYN,BCAP31,VAV1,MRPL50,NRF1,PSMA6,ZNF473,BRPF3,WDR44,PIN1,TARDBP,CABLES2,TOP1MT,STRAP,SPSB3,PRPF19,SNX25,KDM3B,ARHGAP17,CLCN3,BIRC3,RAB7A,NUP155,DCLRE1C,CHMP2B,EIF3H,RHBDF2,IDE,DHX16,RBL1,STK38,UBXN2B,FASTK,UHRF2,AP1S1,XRCC3,H3F3A,SLC22A23,SMAD4,RAD51D,PARD3,BCL2L12,SLC30A9,NADSYN1,MCM10,KLHL21,HMGN3,ARF1,NCAPG,SCYL2,TUBGCP2,DNAJB9,FZD6,HERC3,HOMER1,CTSS,POLR1B,ORC3,RNF5,RNLS,PPAN,RHOA,HMGN5,BTAF1,ABCF2,TUFM,TOP3A,ARHGEF12,PCGF1,ZFR,DDX23,RAB18,TRIM26,PDCD6,ATP6V1D,L3MBTL3,FAM110A,NEIL3,BBX,E2F1,USP20,IMPDH1,RBPJ,NR2F2,PGAM1,HIPK3,NUP188,MAX,PNISR,PDCD6IP,GXYLT1,LUZP1,PRKCSH,ADAM10,TSC22D3,CXXC1,AP3M2,USP39,CUL1,GYG1,UBE2I,PARK7,MYEF2,SLC25A37,ASPHD2,ANKRD26,PA2G4,NOL11,RAB4A,SUCLG2,SMARCE1,CDC5L,SRP72,OSBP2,KLF10,NSUN2,LACTB,USP22,RFC2,CBFB,RAB2B,EIF3A,ZMYM3,IWS1,DOT1L,MAP3K4,ANKRD10,HHEX,WAS,KIF18B,TPP2,LUC7L3,C1orf109,BTF3,PTPDC1,ZMAT3,NMD3,B4GALT2,PTOV1,PRPF38B,RECQL,C9orf78,COX5B,DNAJC5,EWSR1,GSPT2,PRKAA1,VAV2,ANKH,RRM1,DLGAP4,B4GALT1,CYCS,PRPF39,SUPT7L,PSEN1,ZNF79,CNOT3,YY1AP1,SPAG5,C12orf10,FAM192A,RPN1,CEP104,LHX8,KLHL5,ZNRF2,LRRC8D,PPP4R1,MSH2,DAPK1,FBXL7,CYC1,FAM171A1,SYTL3,APOL1,FDFT1,SOCS5,GCC2,PIGT,PRIM2,ELL2,EMB,RDH10,ZNF574,MFNG,C1orf35,GORASP2,ARID1A,ADRB2,MAP2K2,CCT8,MTR,TWISTNB,PHF6,AKAP1,PI4K2A,HMGN2,XRCC5,DERL1,CAT,PFDN5,SLCO4A1,TTC13,GOLGA2,RBMX,MED15,PIAS2,FAM83D,USP32,ARAP1,CEBPG,CABIN1,SMPD4,GPI,CDKN2A,CYTIP,TP53RK,ATXN3,REPS2,RAB11B,RAF1,KIAA0232,BCL2L1,EPM2A,NUDT19,DECR1,CCNA2,SIAH1,RALB,MTMR4,LPIN2,ADCY9,SOCS6,MRPS27,TTC3,TP53BP2,RNASEH2A,AQR,ILKAP,CDK12,SAP30,ANKLE2,BRD4,CDC123,DRAP1,NARF,LRRC8A,ELP4,PKMYT1,ASB13,ERC1,EML4,TRIM28,SUPT16H,RAD51C,CHMP4A,HINT1,DDOST,DGCR8,SAFB,LMBR1,FTSJ1,RWDD4,NCLN,BEND3,XRCC4,EYA2,DYNC1LI2,ADAM23,PRPF4B,NDUFS1,DEPDC1,SLC41A1,MECP2,MANBA,TKT,CBLL1,SECISBP2,POFUT1,HMG20A,HEATR5B,WWP2,JAKMIP1,EBP,RFWD3,AXIN2,PTPN11,MRPL54,MSH6,JMJD4,KAT2A,LONRF3,TMEM126B,RFXANK,RABIF,ADSL,FBXO9,PACS1,BMS1,KCNQ1,ARSK,KIF11,KLF6,MACF1,FADD,MYO1F,CBX3,INF2,ZHX1,PPP1R11,DDX5,DUSP11,WDR62,WDR91,TAF6,ESPL1,DDB1,DEF6,GPR89B,IPO4,FAM83G,POLA2,RORB,PIGM,ZNF76,MTX3,COPA,PTP4A3,UBE2Q1,ABCB10,MRPL19,SF3B2,DST,CDC42,RAB35,JAZF1,GPATCH1,TCEA1,SLC35C2,SRPK2,WDR41,LARS,DEAF1,SNRNP200,CCDC138,NCK1,LAP3,VHL,LRBA,PITPNB,KMT2C,PRPSAP1,ASF1B,MAN2A2,BRWD1,PPM1G,SH3GLB2,MIA2,ACBD4,CAB39,BAZ1B,STK11,CHEK2,CLU,ZSWIM3,MRPL13,CHPT1,DCAF5,UBE2D3,PPP1R2,PPP1R12A,ZCCHC8,NACA,UBXN1,PCSK7,THRAP3,RGS2,PRPF18,NUP205,ZRANB1,MCPH1,SLC12A2,CSNK1G3,TRAFD1,GBA,SYVN1,VKORC1,SLTM,DAPK3,ARHGAP15,EVC2,MASTL,UAP1,KLHL15,NFIL3,SIAH2,FN3KRP,SLC16A1,YWHAZ,EHD4,TOB1,TSEN15,N4BP2L2,ADNP2,TCF12,SNX27,PRKAB1,CORO7,MDH2,PMS2,SMARCA4,ORC1,CLCC1,EXT2,MXD1,USP5,IARS,KIF14,PPP6C,CS,CLTB,DNAL4,EBAG9,CSTF1,POU2AF1,RNF25,METTL2A,PCGF6,ATXN1,GLO1,OGDH,BICD2,TOLLIP,FANCE,PDHX,DUS3L,HNRNPR,HPS5,STAT6,ANP32E,FKBP5,CCDC125,BRD9,MAPK1,ABCA1,TMEM33,DNAJC2,TRIP12,SHPRH,RAE1,SCYL1,NUP54,VPS45,CHIC2,PAWR,MXD4,MYO9B,DCUN1D4,PIP4K2A,GFM2,XPR1,KIF5B,FASTKD3,FGFR3,PPIG,RRBP1,H2AFY,ARHGEF2,ATG13,LDLRAD3,ERI3,STAT3,FRMD8,AMPD2,TGFB1,B3GALT6,DCAF6,FAM49B,PSPC1,HELB,MIER1,ATP2C1,SCFD2,RFFL,COG1,RCOR1,NDRG3,TFEB,MTMR3,UPF1,ELMO1,ZC3H7B,DTX4,CENPT,ZMIZ1,PLOD3,TERF1,HRAS,RAB3IL1,RAB14,FGFR1OP,ADD1,MRPS15,KDM4A,PIGQ,XIAP,AGPAT1,DHX8,GLUD1,CNTROB,PPP1R16B,MIS12,PABPC4,CDK5,PSMD1,NEK6,RABGAP1L,SRSF4,PDS5B,NUP153,SENP1,PCBP2,MLST8,PLK3,PLEKHM3,TOPORS,MCL1,SMC2,PPFIA3,ICMT,TRIM47,PWWP2B,WDR11,AXIN1,LIMK1,ZNF689,ATE1,FBXL3,TFDP2,E2F2,PFKP,DDX42,SSRP1,CERK,TOP2B,SLC4A2,EZH1,ZNRF3,ITGB5,LMNA,MCTS1,RAVER2,DDX56,SLC38A5,INPP5A,INTS7,MCM5,PHF14,ZNF326,FOXN2,ETV3,RB1CC1,TSPYL4,C16orf72,PRRC2A,ZMYND11,DHX29,MAN1B1,TEX10,MYBL2,UHRF1BP1,SRSF5,MPG,MATR3,RHOB,LRRC14B,PTPRF,DTWD1,OSBPL11,DUSP3,SLAIN1,MDH1,CNOT6,NDE1,HEXA,RNF139,SNX14,EGLN1,ZNF207,ZNF296,ABCA3,TRERF1,UBR2,CHD1L,WDTC1,TMEM97,MYH9,NUF2,NIPA2,PRKACA,TCF19,APP,ANKIB1,KTN1,RAB21,PRKD3,SP100,UTP18,DUT,ZCCHC2,NUP107,ANKRD13C,ANAPC7,RNF19A,CEP63,RBM15,ATF2,GCC1,ADCY7,SHOC2,MAP4K4,RNPS1,ATP6V0A1,DNAJA1,TAZ,FKBP3,DDX17,GPR137,TAF2,CDC16,HIPK2,WDR7,CBLN2,MBOAT1,TICAM1,FUS,PDXK,ZBTB11,GEN1,LRP8,LRCH1,GALK1,SESTD1,SIKE1,GMCL1,JMJD6,UBE4A,ETS1,IL21R,ZNF92,KRI1,FBXO3,CAPN2,ERH,SUV39H2,NDUFB4,PPP1R8,GEMIN6,TPCN1,IMPA2,HNRNPM,LDHB,PDPK1,PPP3CA,TK1,TNFAIP3,POLK,GALC,ZNF512,MTMR12,PDE3B,DDX39A,RPA1,ZNF180,KIF18A,KEAP1,POLE,CCDC6,WNT5B,TATDN2,PITX1,MAPK6,CAPN7,LRPPRC,PML,LY75,HMGB2,RGL1,PSAP,WDR76,IGBP1,ANAPC4,FAF1,SNAPIN,COX15,DDX47,AGRN,THOC1,PPP1R15B,MCCC1,CSNK2A1,EBNA1BP2,S1PR2,SEC16A,GIT2,BIRC2,SSR1,LIN9,ABL2,PCNA,ZNF639,PIK3R2,ETV6,XRCC2,MYBL1,MRPL32,CCAR1,CDC37,PTPRK,SP3,BAZ2A,TLK1,GMFB,LNX2,LRP5,BRCA1,ANLN,PRKRA,STX16,RAB5B,RHEB,OPTN,TONSL,NRM,SOCS4,QRSL1,ACTB,GLCCI1,NUDT11,GEMIN7,RACGAP1,PPP3CB,DOCK11,RLF,CRLF3,RAPGEF6,LRRC14,RB1,NUS1,VASP,MED8,VMP1,PPIL2,SLC27A4,AFF1,AHDC1,MAML1,TMEM8A,ABCC1,PREB,CYTH1,TRAPPC9,AACS,RTF1,EIF2AK1,KRAS,UBE4B,ARPC1A,ZNF174,GOLGA4,PALB2,SYNCRIP,CDC27,PRPS2,PRMT7,NIPA1,CYLD,FOXM1,XAB2,SUMO2,DUSP22,COMMD8,RPL11,RAD23A,CSDE1,PDK2,MDM2,STRBP,PDCD2,CORO1A,MINPP1,METTL9,SAP30L,DVL2,POC5,PSMA8,BTG2,CYP20A1,SLC26A6,DNAJC9,MTMR6,NFATC2,PRPF3,ARL5B,RPSA,USP36,SRSF1,MRPL2,DNAJC10,ATP1A1,PLEKHG4B,CLK3,ZNF700,PSMD3,MAFK,CEP55,DNAJC17,NCOA1,LTA4H,USP53,SLC25A39,ZC3HC1,ZNF146,ATXN7L2,INTS2,CTDP1,GOLIM4,SMAP1,RRP15,GNE,CDT1,ARID5A,SMC6,NKRF,CSNK1A1,TFRC,PTPN2,IRF4,ABCD1,SS18L1,DDX31,CAMK2G,RPAP3,CNTN5,MLEC,SNX2,ZNF202,PPWD1,FAM50B,CHCHD6,NEU1,KPNA4,FBXO41,BIRC5,TFE3,GLG1,PGRMC1,FAM126A,RPS6KC1,UBE2C,ZNF496,PPCS,NDUFB6,TMEM41B,ZDHHC8,PLXNA1,CCNB1,IKBIP,SLC20A1,ASAP2,CDC25B,TFG,PLCL2,DNMT1,SEH1L,ORAI2,AKT2,PBK,NOL8,GNG7,MKI67,DDX20,AMDHD2,AURKB,GALNT7,SLC17A5,CCNF,SLC25A5,ZFAND5,RBM47,STT3A,PTER,WDR4,EIF2D,ITGB1,PTPN7,RRS1,TRAF5,ARRB2,ZNF598,HDAC2,DDX58,WSB2,PPIB,MUT,CHTF18,KIF23,NOTCH2,MAN2B1,METTL3,JMY,CFLAR,NDUFS4,FKBP1A,RNF121,MEX3C,SNX18,HDAC7,ATIC,CTPS1,PCYT2,PIKFYVE,RNF135,GNAI2,ANKHD1,EEF1D,TERF2,MORC3,PHF10,DDX28,ZNF84,SIGMAR1,PIP4K2C,KCTD20,DCTD,PLEC,RIT1,KDM3A,FAS,ADSS,EPRS,ZNF777,TMEM54,ZFP92,QARS,ERGIC3,ACLY,PPP3R1,LPCAT4,VCPIP1,YY1,PPP6R3,PPP6R2,MAP3K5,RNF14,CDK2,CABLES1,NRBP1,ZC3HAV1,DNMT3A,TRIP10,ZBTB37,URB2,SUZ12,RPS6KA1,SF3B1,MAGED1,RAC1,OLA1,ADPGK,AP1B1,SDHA,GNB2,PHC2,FLAD1,CRKL,TERF2IP,APLP2,ZNF75D,SHC1,KDM2A,UCHL5,TNPO2,CDKN1B,CCT2,MAPRE2,RFC3,ATP13A1,MKLN1,HMGN4,ERF,CUL3,KIAA1586,GALK2,CDC23,GAR1,POLG2,DHX57,HSPA4,JAK1,PPP2R5A,MRPL55,ACYP1,TBL3,H2AFX,SEL1L,STAT1,KLHDC4,TRIM32,B4GALT3,PDCD11,RHEBL1,POLQ,OTUD5,NCOR2,SCAMP3,C1orf112,TCF3,BRAP,BLM,FOXO3,RAB11A,MAD2L2,TMCC3,GTF2F1,PIP5K1C,MAT2B,PTEN,CRAT,AHSA1,CENPJ,PRC1,UPF2,COPS7B,CNOT6L,CREB1,UBE2M,NCOA2,SMC4,TSHZ1,NET1,NEK7,DENND1B,DENND4C,ILF3,PARP4,TBRG4,ANAPC2,RHOT1,MARK2,TSR2,PRDX1,PLD3,FBXO21,GNA12,PFDN4,TTLL4,PRDX3,SLC38A7,MFAP1,TFDP1,KHSRP,BRWD3,ESYT2,MIB2,IER2,UBE2E2,SKA3,PLXNC1,ST13,DCAF15,NF1,FLYWCH2,ZNF107,AGFG1,SIRT2,KIF2C,FKBP2,USP48,UBQLN2,MAPK14,BECN1,SNAPC4,RNF103,BCAT2,MBD4,UBLCP1,ZNF804A,RAP1A,EIF4A3,THADA,PPP1R12C,SRI,KIF22,JOSD1,RP2,OGG1,ARID4A,TRIM14,COPS8,FYTTD1,TRIM8,SLC16A7,RRM2,WDR82,SLC25A22,SOX4,STK17B,UBTF,CXXC4,PAF1,GEMIN5,UEVLD,PQBP1,ATXN2L,IARS2,GALNT10,COPS6,STARD3NL,SLC12A7,PIGN,TM9SF4,CIB1,MED13L,TIA1,MEF2A,XPO7,EPHX2,RHBDD1,NFATC3,ZNF449,ZNF335,KIFAP3,BCL2,KNTC1,UBE3C,N4BP2,ALDH9A1,ZNF189,TSTA3,CIC,OXR1,SEPT7,CAND1,GNAS,TSC1,RBM25,ODF2,EXOC4,PITPNA,NUP62,NANP,RBBP4,MZT2B,PTDSS1,C7orf26,SMARCD1,WASF2,MBD1,TMEM106C,ASH1L,GNPNAT1,WDYHV1,HNRNPUL2,PLAGL2,TWF2,CHD1,CCDC50,SAR1A,AKAP8,APOOL,CHTOP,FAM3A,PDIA6,SCYL3,ABI1,MOSPD1,RLIM,ZNF500,NLN,WIPF1,TOR1AIP2,PEF1,BTBD1,RAD54B,DAP3,TMEM41A,TAB2,TULP3,WDR59,CANT1,SCARB1,GAS2,USP11,AKNA,SMURF1,TSPAN5,PPP2R2D,CBX4,KIF3B,CDS2,MAGEH1,SH2D3A,CASP6,EYA1,TOR3A,DBF4,LETMD1,RGS1,HDDC2,MAN1A1,FBXO5,GART,CTNNBL1,TANK,BRD7,YIF1B,TTC17,MRPL11,GINS1,TELO2,CSNK1G2,ADAM17,HMGN1,NASP,ASPM,PRKAR1B,WDR81,MEN1,ZNF407,SYMPK,MFN2,MAPK3,ATAD2,ZNF330,COX8A,KBTBD7,ZRANB2,SRSF3,MBD6,TATDN1,PREPL,IDH3B |
| 3.517e-02 | -3.35 | GGCKCATGS_UNKNOWN | MSigDB lists | GGCKCATGS_UNKNOWN | 61 | 15 | 17377 | 2626 |
PTPN2,SDHB,INTS7,NF1,FUT8,RDH10,RAB23,NDUFS8,PRPF39,USF2,CBFB,CCAR1,SMAP2,MORC3,C14orf119 |
| 3.517e-02 | -3.35 | REACTOME_ACTIVATION_OF_NF_KAPPAB_IN_B_CELLS | MSigDB lists | REACTOME_ACTIVATION_OF_NF_KAPPAB_IN_B_CELLS | 61 | 15 | 17377 | 2626 |
PSMD2,PSMD1,PSMA6,PSMA8,RPS27A,PSMD8,PSMD3,PSMB7,PSMA1,CUL1,PSMB9,PSMD9,PSMC1,PSMB3,PSMC4 |
| 3.517e-02 | -3.35 | MODULE_254 | MSigDB lists | MODULE_254 | 61 | 15 | 17377 | 2626 |
PLK1,PCNA,NRAS,BIRC3,BIRC5,MKI67,MYBL2,E2F1,E2F3,BCL2L1,CCNB1,STK17B,BIRC2,FAS,CFLAR |
| 3.517e-02 | -3.35 | PID_AR_PATHWAY | MSigDB lists | PID_AR_PATHWAY | 61 | 15 | 17377 | 2626 |
PA2G4,PRKDC,PAWR,BRCA1,ZMIZ1,CDK11B,UBE2I,KDM3A,APPL1,CTDSP2,PRDX1,NCOA2,CDKN2A,CARM1,XRCC5 |
| 3.518e-02 | -3.35 | ELP6 (elongator acetyltransferase complex subunit 6) | protein interactions | 54859 | 29 | 9 | 17029 | 2761 |
PSMA6,ELP5,ZNF639,KLHL15,ELP4,PSMB3,IWS1,SRPK2,PSMC4 |
| 3.518e-02 | -3.35 | PRC1 (protein regulator of cytokinesis 1) | protein interactions | 9055 | 29 | 9 | 17029 | 2761 |
PLK1,CCNA2,FOXM1,KIF23,RACGAP1,CCNB1,WDR5,CDK2,DCTN1 |
| 3.518e-02 | -3.35 | FBXO31 (F-box protein 31) | protein interactions | 79791 | 29 | 9 | 17029 | 2761 |
MDM2,ZCCHC9,PDLIM1,FOXM1,RBX1,CDT1,MRPS27,CUL1,EDRF1 |
| 3.518e-02 | -3.35 | INTS11 (integrator complex subunit 11) | protein interactions | 54973 | 29 | 9 | 17029 | 2761 |
INTS2,PLK1,PPP2CA,TK1,INTS7,INTS1,NABP1,CBWD1,POLR2A |
| 3.518e-02 | -3.35 | HTR6 (5-hydroxytryptamine receptor 6) | protein interactions | 3362 | 29 | 9 | 17029 | 2761 |
CDK5,GNAS,TELO2,NSF,NF1,DNM2,NCAPG,COPG2,NCDN |
| 3.518e-02 | -3.35 | SCLY (selenocysteine lyase) | protein interactions | 51540 | 29 | 9 | 17029 | 2761 |
TERF2IP,GNS,IDE,UAP1,WDR1,LNX2,NUTF2,EIF5,TFG |
| 3.518e-02 | -3.35 | ATP6AP1 (ATPase H+ transporting accessory protein 1) | protein interactions | 537 | 29 | 9 | 17029 | 2761 |
HNRNPAB,RAB7A,TMEM216,ATP6V0A2,SYVN1,ATP6V1C1,MYEF2,ATP6V0D1,EVC2 |
| 3.518e-02 | -3.35 | VPS41 (VPS41, HOPS complex subunit) | protein interactions | 27072 | 29 | 9 | 17029 | 2761 |
UTP20,RAB7A,NABP2,MON1B,PTAR1,VIPAS39,CLTB,XRCC4,APP |
| 3.518e-02 | -3.35 | Actr1b (ARP1 actin-related protein 1B, centractin beta) | protein interactions | 226977 | 29 | 9 | 17029 | 2761 |
CCT2,MTA1,DCTN2,CAPZA1,CAPZA2,YWHAH,CCT8,PDCL3,DCTN1 |
| 3.518e-02 | -3.35 | DEGS1 (delta 4-desaturase, sphingolipid 1) | protein interactions | 8560 | 29 | 9 | 17029 | 2761 |
NAGPA,SLC16A1,CYHR1,SIRT2,SURF4,HDGFL2,C4orf3,LSG1,GTF2F1 |
| 3.518e-02 | -3.35 | NOSIP (nitric oxide synthase interacting protein) | protein interactions | 51070 | 29 | 9 | 17029 | 2761 |
UBE2D3,PPP2CA,KPNA1,NF1,PTPN11,CUL3,MCM2,DDX42,DDX17 |
| 3.518e-02 | -3.35 | IER2 (immediate early response 2) | protein interactions | 9592 | 29 | 9 | 17029 | 2761 |
KPNA4,MDM2,NSMCE4A,GALC,NUP153,CDCA2,GLE1,HDGFL2,PPP2R2D |
| 3.518e-02 | -3.35 | FRMD6 (FERM domain containing 6) | protein interactions | 122786 | 29 | 9 | 17029 | 2761 |
TCF12,WDR7,KCTD17,GMCL1,JMJD6,TP53BP2,YWHAH,MAK16,APP |
| 3.518e-02 | -3.35 | TBPL1 (TATA-box binding protein like 1) | protein interactions | 9519 | 29 | 9 | 17029 | 2761 |
NF1,RAB35,FUS,TAF6,PMVK,TERF1,APP,PRNP,TERF2 |
| 3.518e-02 | -3.35 | ERO1A (endoplasmic reticulum oxidoreductase 1 alpha) | protein interactions | 30001 | 29 | 9 | 17029 | 2761 |
HSPBP1,PPME1,ERO1A,WDR4,H2AFX,DDX5,LRSAM1,LYN,ATF2 |
| 3.518e-02 | -3.35 | EXO1 (exonuclease 1) | protein interactions | 9156 | 29 | 9 | 17029 | 2761 |
KPNA4,PCNA,PMS2,MSH2,YWHAZ,UBE2I,BLM,YWHAH,MYEF2 |
| 3.518e-02 | -3.35 | PRPSAP2 (phosphoribosyl pyrophosphate synthetase associated protein 2) | protein interactions | 5636 | 29 | 9 | 17029 | 2761 |
NAPG,LZTR1,IVNS1ABP,PRPS2,UBXN1,PRKAR1B,CCNB1,PRPSAP1,APP |
| 3.522e-02 | -3.35 | Sialic acid metabolism | REACTOME pathways | R-HSA-4085001 | 33 | 10 | 10287 | 1696 |
CMAS,GNE,CTSA,ST3GAL2,SLC17A5,NANS,NANP,ST8SIA2,SLC35A1,NEU1 |
| 3.522e-02 | -3.35 | ROS, RNS production in phagocytes | REACTOME pathways | R-HSA-1222556 | 33 | 10 | 10287 | 1696 |
ATP6V0B,ATP6V1D,ATP6V0A2,ATP6V0A1,ATP6V0C,ATP6V1C1,ATP6V1B2,ATP6V0E1,ATP6V0D1,ATP6V1G1 |
| 3.525e-02 | -3.35 | PIAS4 (protein inhibitor of activated STAT 4) | protein interactions | 51588 | 97 | 23 | 17029 | 2761 |
IMMT,MAGEH1,VHL,BTAF1,SUMO2,GADD45G,IRF3,BRCA1,UBE2I,ETS1,OPTN,SMAD2,CHD3,ZHX1,PIAS2,TICAM1,KNTC1,TRIM32,SMAD1,OAZ1,SMAD4,COIL,HDAC2 |
| 3.533e-02 | -3.34 | vpu (p16) | protein interactions | 155945 | 257 | 53 | 17029 | 2761 |
MIF,SCAMP3,HLA-E,UROD,FLOT1,CUL1,CSNK2A1,TGOLN2,IRF3,BCL2L1,ATP5F1B,AP1B1,ATP5PF,SCYL2,TFRC,HLA-A,NPLOC4,NFATC3,AP1M1,DNM2,HADHB,SLC27A4,MAVS,CYB5R1,PTGES3,CSNK1G3,APOL1,PREB,CHP1,TGFB1,PLK1,SELPLG,PRKDC,ACSL3,TBRG4,NFATC2,SRSF5,WDR81,ICAM2,ISG15,FAS,PPP2CA,HLA-B,HGS,GOLGA4,STAT1,LRPPRC,AP1S1,VPS4A,CD81,RTN3,DDB1,IFI16 |
| 3.535e-02 | -3.34 | skin-lower_leg-carcinoma-squamous_cell_carcinoma | COSMIC cancer mutations | skin-lower_leg-carcinoma-squamous_cell_carcinoma | 22 | 7 | 17385 | 2587 |
FGFR3,KRAS,NOTCH2,NRAS,VHL,HRAS,CDKN2A |
| 3.535e-02 | -3.34 | bronchus | COSMIC cancer mutations | bronchus | 22 | 7 | 17385 | 2587 |
FGFR3,KRAS,STK11,NRAS,PTEN,HRAS,SMAD4 |
| 3.535e-02 | -3.34 | skin-arm-carcinoma-squamous_cell_carcinoma | COSMIC cancer mutations | skin-arm-carcinoma-squamous_cell_carcinoma | 22 | 7 | 17385 | 2587 |
FGFR3,KRAS,NOTCH2,NRAS,VHL,HRAS,CDKN2A |
| 3.538e-02 | -3.34 | DNA topological change | biological process | GO:0006265 | 9 | 4 | 17256 | 2622 |
TOP2B,HMGB2,TOP1MT,TOP3A |
| 3.538e-02 | -3.34 | pyrimidine deoxyribonucleotide biosynthetic process | biological process | GO:0009221 | 9 | 4 | 17256 | 2622 |
DCTD,DUT,HDDC2,TBPL1 |
| 3.538e-02 | -3.34 | telomeric D-loop disassembly | biological process | GO:0061820 | 9 | 4 | 17256 | 2622 |
BLM,POT1,TERF1,TERF2 |
| 3.538e-02 | -3.34 | histone H4-K20 methylation | biological process | GO:0034770 | 9 | 4 | 17256 | 2622 |
BEND3,KMT5C,KMT5A,ARID4A |
| 3.538e-02 | -3.34 | endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) | biological process | GO:0000447 | 9 | 4 | 17256 | 2622 |
KRI1,UTP20,RRS1,RPSA |
| 3.538e-02 | -3.34 | positive regulation of tumor necrosis factor-mediated signaling pathway | biological process | GO:1903265 | 9 | 4 | 17256 | 2622 |
CPNE1,ADAM17,TRIM32,HSPA1B |
| 3.538e-02 | -3.34 | response to sterol depletion | biological process | GO:0006991 | 9 | 4 | 17256 | 2622 |
EIF2A,SCAP,LYN,ERLIN1 |
| 3.538e-02 | -3.34 | outer ear morphogenesis | biological process | GO:0042473 | 9 | 4 | 17256 | 2622 |
PRKRA,MAPK1,EYA1,MAPK3 |
| 3.538e-02 | -3.34 | RNA polymerase I transcriptional preinitiation complex assembly | biological process | GO:0001188 | 9 | 4 | 17256 | 2622 |
SMARCA4,UBTF,RRN3,BAZ2A |
| 3.538e-02 | -3.34 | antibiotic transport | biological process | GO:0042891 | 9 | 4 | 17256 | 2622 |
SFXN5,MFSD10,SLC25A1,SLC26A6 |
| 3.540e-02 | -3.34 | RNA cap binding | molecular function | GO:0000339 | 17 | 6 | 17224 | 2647 |
GEMIN5,CYFIP1,SNUPN,CYFIP2,EIF3D,AGO2 |
| 3.543e-02 | -3.34 | WONG_IFNA2_RESISTANCE_DN | MSigDB lists | WONG_IFNA2_RESISTANCE_DN | 31 | 9 | 17377 | 2626 |
ATP6V0B,PDK2,HMGN1,LZTR1,MKLN1,DUSP3,PSMD8,MSH2,HNRNPF |
| 3.543e-02 | -3.34 | GO_IMMUNOLOGICAL_SYNAPSE | MSigDB lists | GO_IMMUNOLOGICAL_SYNAPSE | 31 | 9 | 17377 | 2626 |
SNX27,PDCD6IP,DUSP3,SOCS6,MYH9,EZR,CORO1A,CD81,STOML2 |
| 3.543e-02 | -3.34 | SIMBULAN_UV_RESPONSE_IMMORTALIZED_DN | MSigDB lists | SIMBULAN_UV_RESPONSE_IMMORTALIZED_DN | 31 | 9 | 17377 | 2626 |
NAP1L1,AHNAK,JAK1,TACC1,RRM2,TOP2B,PLEC,ROCK1,SF3A2 |
| 3.543e-02 | -3.34 | REACTOME_LATENT_INFECTION_OF_HOMO_SAPIENS_WITH_MYCOBACTERIUM_TUBERCULOSIS | MSigDB lists | REACTOME_LATENT_INFECTION_OF_HOMO_SAPIENS_WITH_MYCOBACTERIUM_TUBERCULOSIS | 31 | 9 | 17377 | 2626 |
ATP6V0B,ATP6V1D,ATP6V0A2,ATP6V0C,ATP6V1B2,ATP6V1C1,ATP6V0E1,ATP6V0D1,ATP6V1G1 |
| 3.543e-02 | -3.34 | REACTOME_CD28_CO_STIMULATION | MSigDB lists | REACTOME_CD28_CO_STIMULATION | 31 | 9 | 17377 | 2626 |
PDPK1,VAV1,CDC42,AKT2,RAC1,PIK3R2,MAP3K14,LYN,MLST8 |
| 3.543e-02 | -3.34 | PID_AR_NONGENOMIC_PATHWAY | MSigDB lists | PID_AR_NONGENOMIC_PATHWAY | 31 | 9 | 17377 | 2626 |
CDC42,RAF1,RAC1,CREB1,MAPK1,GNAI2,HRAS,MAP2K2,MAPK3 |
| 3.543e-02 | -3.34 | GO_ATP_HYDROLYSIS_COUPLED_TRANSMEMBRANE_TRANSPORT | MSigDB lists | GO_ATP_HYDROLYSIS_COUPLED_TRANSMEMBRANE_TRANSPORT | 31 | 9 | 17377 | 2626 |
ATP6V0B,ATP1A1,ATP6V0A1,ATP6V0A2,ATP6V0C,ATP6V1B2,ATP6V1C1,ATP6V0E1,ATP6V0D1 |
| 3.543e-02 | -3.34 | GO_ATP_DEPENDENT_DNA_HELICASE_ACTIVITY | MSigDB lists | GO_ATP_DEPENDENT_DNA_HELICASE_ACTIVITY | 31 | 9 | 17377 | 2626 |
RECQL,CHD3,HELB,CHD1L,DHX9,RUVBL2,BLM,CHD1,XRCC5 |
| 3.543e-02 | -3.34 | GO_POSITIVE_REGULATION_OF_RESPONSE_TO_CYTOKINE_STIMULUS | MSigDB lists | GO_POSITIVE_REGULATION_OF_RESPONSE_TO_CYTOKINE_STIMULUS | 31 | 9 | 17377 | 2626 |
CPNE1,AGPAT2,AGPAT1,NLRC5,MAVS,TRIM32,IRF3,FADD,HSPA1B |
| 3.543e-02 | -3.34 | ZHAN_V1_LATE_DIFFERENTIATION_GENES_UP | MSigDB lists | ZHAN_V1_LATE_DIFFERENTIATION_GENES_UP | 31 | 9 | 17377 | 2626 |
CAT,RB1,APLP2,TIMP2,TNFAIP3,BIRC3,NAGLU,B4GALT1,ATP6V1B2 |
| 3.545e-02 | -3.34 | BROWNE_HCMV_INFECTION_16HR_UP | MSigDB lists | BROWNE_HCMV_INFECTION_16HR_UP | 217 | 43 | 17377 | 2626 |
RMND5A,CCNC,TBC1D12,CDC40,MPHOSPH8,PPP1R2,SUZ12,RAF1,DNAJC24,DHX8,ARFIP2,SIKE1,PRKACA,CRLF3,LYN,TTF1,CHD1,TFRC,SSR1,CREM,MOAP1,PRKD3,POP7,PTPN11,NUP153,SRSF10,SAP30,CDC5L,PRPF19,BAK1,CAMSAP1,WDR82,CDC6,MAT2A,RAD51C,SEC23IP,SLC16A1,FKBP5,PRPF4,TRIM52,ZNF45,FUBP1,NXT2 |
| 3.546e-02 | -3.34 | amide transmembrane transporter activity | molecular function | GO:0042887 | 45 | 12 | 17224 | 2647 |
SLC19A1,SEC61B,TOMM20,SEC61G,SLC38A7,TIMM23,TIMM17A,TAP1,MCL1,TAP2,TOMM40,ABCC1 |
| 3.556e-02 | -3.34 | TMEM30A (transmembrane protein 30A) | protein interactions | 55754 | 62 | 16 | 17029 | 2761 |
UNK,TMED7,NSDHL,TMX4,TMED3,CLCC1,EDEM2,STK17B,APP,DNAJB9,PON2,HLA-B,SARAF,UPK3BL1,CYB5R1,APOL2 |
| 3.556e-02 | -3.34 | COPS8 (COP9 signalosome subunit 8) | protein interactions | 10920 | 62 | 16 | 17029 | 2761 |
COPS8,MAPRE1,RAE1,CUL3,CUL1,KRAS,GFER,SRRT,BTBD1,DTL,DDA1,DCAF11,FEM1B,COPS7B,COPS6,DDB1 |
| 3.556e-02 | -3.34 | PCBD1 (pterin-4 alpha-carbinolamine dehydratase 1) | protein interactions | 5092 | 62 | 16 | 17029 | 2761 |
WDYHV1,WDR1,ZNF202,EHMT1,CUL3,CUL1,KLF13,RPS24,GORASP2,APP,ADSS,BRD7,TIMELESS,DVL2,SMARCD1,SAP30 |
| 3.556e-02 | -3.34 | THAP7 (THAP domain containing 7) | protein interactions | 80764 | 62 | 16 | 17029 | 2761 |
ASH1L,NOP2,DDX24,ASPM,ZNF512,EBNA1BP2,MAP1LC3B,APP,PHC2,TRIM26,GOLGA2,RPL32,RPS27A,NIP7,RBM34,PIN1 |
| 3.556e-02 | -3.34 | COMTD1 (catechol-O-methyltransferase domain containing 1) | protein interactions | 118881 | 62 | 16 | 17029 | 2761 |
IFRD1,PBXIP1,DNAAF5,ADSL,DDX20,PNO1,CIP2A,SUGP1,GEMIN5,EPRS,IARS,TNPO3,TNPO2,UPF2,PHKG2,PDCD4 |
| 3.556e-02 | -3.34 | S1P4 pathway | Pathway Interaction DB | s1p_s1p4_pathway | 14 | 6 | 2226 | 426 |
GNA12,RHOA,CDC42,MAPK1,GNAI2,MAPK3 |
| 3.561e-02 | -3.34 | GO_CENTRIOLE | MSigDB lists | GO_CENTRIOLE | 93 | 21 | 17377 | 2626 |
POC1A,TOPORS,SIRT2,CNTROB,CCNF,HSPA1B,RAB8A,CEP104,STARD9,PCM1,CCP110,BIRC5,CENPJ,ODF2,CEP55,ROCK1,RP2,CEP63,WDR62,SASS6,POC5 |
| 3.563e-02 | -3.33 | Regulation of Telomerase | Pathway Interaction DB | telomerasepathway | 66 | 19 | 2226 | 426 |
TGFB1,SP3,MAX,BLM,MXD1,MAPK3,XRCC5,TERF2IP,E2F1,CDKN1B,PTGES3,NR2F2,RBBP4,MAPK1,TERF1,POT1,HDAC2,TERF2,SAP30 |
| 3.563e-02 | -3.33 | Signaling events mediated by HDAC Class I | Pathway Interaction DB | hdac_classi_pathway | 66 | 19 | 2226 | 426 |
NCOR2,MAX,MTA2,RANGAP1,SIRT2,UBE2I,MBD3,PRKACA,FKBP3,MXD1,CHD3,HDAC7,MBD2,YY1,RBBP4,STAT3,SMURF1,HDAC2,SAP30 |
| 3.563e-02 | -3.33 | COIL (coilin) | protein interactions | 8161 | 92 | 22 | 17029 | 2761 |
ZCCHC10,POLR2L,WDYHV1,SNRPB,SCYL1,PSMA1,ATXN1,LACTB2,CDC23,APP,XRCC5,GTF2F1,DHX16,MFAP1,KLHL42,PREPL,CDK2,PDLIM5,GCC1,COIL,IFI16,BYSL |
| 3.563e-02 | -3.33 | LASP1 (LIM and SH3 protein 1) | protein interactions | 3927 | 92 | 22 | 17029 | 2761 |
FYTTD1,NCOR2,ACTR3,EZR,ATXN1,SLC25A44,DAZAP2,API5,AHNAK,GOLGA2,DNAAF2,MAP4,ACTB,STAT3,CD81,DNMT1,TERF1,CDK12,POT1,DDB1,DCTN1,SPTAN1 |
| 3.564e-02 | -3.33 | KAAB_HEART_ATRIUM_VS_VENTRICLE_DN | MSigDB lists | KAAB_HEART_ATRIUM_VS_VENTRICLE_DN | 252 | 49 | 17377 | 2626 |
NDUFV2,NDUFS1,IVNS1ABP,EYA1,CDK2AP2,STARD7,TWF2,SDHA,NDUFS7,BCAT2,CAPN2,RAB21,DECR1,GOT2,BDH1,PCYT2,CYB5R1,CYC1,IMPA2,LDHB,MAPKAPK3,LYRM1,ACSL3,AMD1,HEBP2,KCNQ1,OGDH,VDAC1,PDHX,CYB5A,ECH1,SDHB,GNAS,PDLIM1,PRDX3,ZNF330,MAP4,COX8A,ACAT1,COX5A,MAP3K5,IDH3B,TMEM159,PDLIM5,HRAS,TOB1,HIPK3,PFKP,ADAM23 |
| 3.566e-02 | -3.33 | GSE29164_UNTREATED_VS_CD8_TCELL_TREATED_MELANOMA_DAY7_UP | MSigDB lists | GSE29164_UNTREATED_VS_CD8_TCELL_TREATED_MELANOMA_DAY7_UP | 194 | 39 | 17377 | 2626 |
SEPHS2,PRKCSH,UFC1,UBXN1,FLOT1,MEF2A,AGPAT3,SLC35B1,SLC35B2,BLM,MIEN1,LYN,FOXO3,BZW2,ATP6V0B,RRBP1,F2R,ZNRD1,CSNK1G2,PPP3CA,DDX24,ELL2,DENND4C,WDR81,IL12RB1,C9orf40,VKORC1,CYFIP2,PRPSAP1,ABCF1,PSMB3,NECAP2,MYO1F,HHEX,SEC61A1,CTSA,PDXK,TMEM159,EYA2 |
| 3.566e-02 | -3.33 | TONKS_TARGETS_OF_RUNX1_RUNX1T1_FUSION_MONOCYTE_UP | MSigDB lists | TONKS_TARGETS_OF_RUNX1_RUNX1T1_FUSION_MONOCYTE_UP | 194 | 39 | 17377 | 2626 |
RMND5A,MDH2,SMARCA4,EBNA1BP2,FAM136A,SLC20A1,ITGB5,GLRX3,BZW2,APLP2,HOMER1,PA2G4,SIVA1,DNAAF2,PPME1,TRMU,FJX1,UBA5,TNPO2,SEH1L,SPTAN1,EIF5A,AMPD2,DDX24,CDC123,GTPBP4,ARHGEF12,MTX1,SOX4,ICAM2,LY6E,ISG15,EPRS,SLCO4A1,KHSRP,SLC16A1,NCLN,PFKP,GCSH |
| 3.566e-02 | -3.33 | GSE339_CD8POS_VS_CD4CD8DN_DC_DN | MSigDB lists | GSE339_CD8POS_VS_CD4CD8DN_DC_DN | 194 | 39 | 17377 | 2626 |
RECQL,DNMT3A,CXXC1,MDH2,TRIM11,GLUD1,KIF2C,UBQLN2,MAPK14,CRLF3,MAN1A1,GTF2F1,PRNP,RTKN,DECR1,AQR,S100A6,GPX4,CLPTM1,VOPP1,CYFIP1,BAZ2A,TSPYL4,GABPA,NCK1,EMB,CRNKL1,EMP3,MCM2,API5,MYO1F,KPNA1,VPS26B,ADAM9,RGL1,PDXK,B4GALT3,CDK2,S100PBP |
| 3.576e-02 | -3.33 | somatic stem cell population maintenance | biological process | GO:0035019 | 66 | 16 | 17256 | 2622 |
POLR2I,SMAD2,KLF10,POLR2G,POLR2L,POLR2J,POLR2K,RAF1,LDB1,POLR2D,LRP5,RBPJ,SOX4,STAT3,SMAD4,POLR2A |
| 3.581e-02 | -3.33 | intercellular bridge | cellular component | GO:0045171 | 57 | 14 | 18223 | 2701 |
SNRNP25,DNAJC8,THOC1,RAB35,XPA,CEP55,CDCA8,RFXANK,TPX2,KIF23,DUSP11,FAM50B,PRKACA,KRR1 |
| 3.584e-02 | -3.33 | Pro_isomerase | pfam domains | PF00160 | 22 | 7 | 17054 | 2545 |
PPIF,PPIB,PPWD1,CWC27,PPIG,PPIE,PPIL2 |
| 3.586e-02 | -3.33 | endoplasmic reticulum tubular network organization | biological process | GO:0071786 | 13 | 5 | 17256 | 2622 |
ZFYVE27,RAB18,RTN3,TMEM33,ARL6IP1 |
| 3.586e-02 | -3.33 | nucleotide-sugar transmembrane transport | biological process | GO:0015780 | 13 | 5 | 17256 | 2622 |
SLC35B1,TMEM241,SLC35C2,SLC35A1,SLC35B4 |
| 3.586e-02 | -3.33 | polyamine biosynthetic process | biological process | GO:0006596 | 13 | 5 | 17256 | 2622 |
SRM,ODC1,OAZ1,AMD1,OAZ2 |
| 3.586e-02 | -3.33 | CD4-positive or CD8-positive, alpha-beta T cell lineage commitment | biological process | GO:0043369 | 13 | 5 | 17256 | 2622 |
BCL2,IRF4,CYLD,STAT3,STAT6 |
| 3.586e-02 | -3.33 | meiotic spindle organization | biological process | GO:0000212 | 13 | 5 | 17256 | 2622 |
MYH9,GOLGA2,ESPL1,ASPM,FBXO5 |
| 3.586e-02 | -3.33 | CDP-diacylglycerol biosynthetic process | biological process | GO:0016024 | 13 | 5 | 17256 | 2622 |
AGPAT3,CDS2,AGPAT2,LCLAT1,AGPAT1 |
| 3.586e-02 | -3.33 | response to UV-C | biological process | GO:0010225 | 13 | 5 | 17256 | 2622 |
MAP3K4,BAK1,HMGN1,MDM2,YY1 |
| 3.586e-02 | -3.33 | telomere maintenance via recombination | biological process | GO:0000722 | 13 | 5 | 17256 | 2622 |
SMC6,XRCC3,RAD51C,ERCC1,NSMCE2 |
| 3.586e-02 | -3.33 | establishment of protein localization to chromosome | biological process | GO:0070199 | 13 | 5 | 17256 | 2622 |
H2AFY,RUVBL2,POT1,SGF29,NABP2 |
| 3.586e-02 | -3.33 | mitochondrial transcription | biological process | GO:0006390 | 13 | 5 | 17256 | 2622 |
MTERF1,FOXO3,TWNK,SLC25A33,MRPL12 |
| 3.586e-02 | -3.33 | peptidyl-lysine dimethylation | biological process | GO:0018027 | 13 | 5 | 17256 | 2622 |
ASH1L,SUV39H2,KDM3A,SETD3,EHMT1 |
| 3.586e-02 | -3.33 | positive regulation of ERAD pathway | biological process | GO:1904294 | 13 | 5 | 17256 | 2622 |
ATXN3,UBQLN2,EDEM2,BCAP31,USP13 |
| 3.586e-02 | -3.33 | Notch receptor processing, ligand-dependent | biological process | GO:0035333 | 13 | 5 | 17256 | 2622 |
YBX1,PSEN1,ADAM10,APH1A,APH1B |
| 3.586e-02 | -3.33 | acetyl-CoA biosynthetic process | biological process | GO:0006085 | 13 | 5 | 17256 | 2622 |
ACAT1,MLYCD,PDHX,MPC1,ACLY |
| 3.590e-02 | -3.33 | RIPK1-mediated regulated necrosis | REACTOME pathways | R-HSA-5213460 | 16 | 6 | 10287 | 1696 |
BIRC3,BIRC2,FADD,CFLAR,XIAP,FAS |
| 3.590e-02 | -3.33 | Regulated Necrosis | REACTOME pathways | R-HSA-5218859 | 16 | 6 | 10287 | 1696 |
BIRC3,BIRC2,FADD,CFLAR,XIAP,FAS |
| 3.590e-02 | -3.33 | Spry regulation of FGF signaling | REACTOME pathways | R-HSA-1295596 | 16 | 6 | 10287 | 1696 |
PPP2CA,MKNK1,MAPK1,RPS27A,MAPK3,PTPN11 |
| 3.591e-02 | -3.33 | B cell differentiation | biological process | GO:0030183 | 98 | 22 | 17256 | 2622 |
SP3,BAK1,ADAM17,PRKDC,TCF3,MFNG,LRRC8A,ITM2A,NOTCH2,DCLRE1C,DOCK11,KLF6,DNAJB9,PTPN2,HHEX,GPS2,ITGB1,MSH2,CEBPG,BCL2,RBPJ,PLCL2 |
| 3.593e-02 | -3.33 | WWP1 (WW domain containing E3 ubiquitin protein ligase 1) | protein interactions | 11059 | 87 | 21 | 17029 | 2761 |
UBE2D3,HIVEP3,PHF20L1,LZTR1,EWSR1,WBP2,EZR,WBP1,DIDO1,DAZAP2,XRCC5,WWP2,SMAD2,PTEN,STAT6,SARAF,ARRDC1,TP53BP2,SMAD1,SMAD4,DVL2 |
| 3.597e-02 | -3.32 | ZFR (zinc finger RNA binding protein) | protein interactions | 51663 | 67 | 17 | 17029 | 2761 |
STAU1,VDAC2,CUL3,RNPS1,BRCA1,USP48,VPS25,PRDX1,RPA1,CAND1,RPA2,HNRNPR,QARS,RPAP1,TARDBP,DNMT1,VPS29 |
| 3.597e-02 | -3.32 | PDIA4 (protein disulfide isomerase family A member 4) | protein interactions | 9601 | 67 | 17 | 17029 | 2761 |
EWSR1,PPP1R2,ERO1A,GADD45G,TUFM,ILF3,NENF,BRCA1,BCL2L1,TWF2,CAPN2,PPME1,H2AFX,TATDN1,YWHAH,ATF2,CDK2 |
| 3.597e-02 | -3.32 | ERG28 (ergosterol biosynthesis 28 homolog) | protein interactions | 11161 | 67 | 17 | 17029 | 2761 |
NAT9,TK1,ZFP64,DYNLL1,SNRPB,FXR1,LMNA,FAS,CDC42,KLHL20,NSF,HNRNPH3,PPP1R8,PQBP1,SNRPG,TFG,CREB1 |
| 3.597e-02 | -3.32 | PAK4 (p21 (RAC1) activated kinase 4) | protein interactions | 10298 | 67 | 17 | 17029 | 2761 |
GGNBP2,CDC42,LIMK1,KIF13B,RAC1,PTPN7,YWHAZ,KLHL42,RAB3IP,NAA20,ITGB5,CARMIL1,POT1,APP,TERF1,CDC5L,SRPK2 |
| 3.597e-02 | -3.32 | PCNT (pericentrin) | protein interactions | 5116 | 67 | 17 | 17029 | 2761 |
MZT1,MAPRE1,EID1,MTA2,SUZ12,RACGAP1,IKBIP,MBD3,TUBGCP2,PON2,PCM1,CHD3,CENPJ,CEP55,YWHAZ,CEP63,CDC5L |
| 3.597e-02 | -3.32 | SOCS1 (suppressor of cytokine signaling 1) | protein interactions | 8651 | 67 | 17 | 17029 | 2761 |
CRKL,VAV1,FGFR3,CYTIP,TRIM8,JAK1,PTEN,NCK1,VHL,PIK3R2,ETV6,VAV2,ELOA,PTPN11,JOSD1,IRF3,MAP3K5 |
| 3.597e-02 | -3.32 | LSM2 (LSM2 homolog, U6 small nuclear RNA and mRNA degradation associated) | protein interactions | 57819 | 67 | 17 | 17029 | 2761 |
SNRPB,RBM8A,ILF3,DDX20,LSM8,PRPF3,DNAJA1,SNRPD3,CLNS1A,SF3B2,KIF5B,DHX16,LSM6,CWC27,BUD31,PRPF4,DDB1 |
| 3.599e-02 | -3.32 | soft_tissue-fibrous_tissue_and_uncertain_origin-synovial_sarcoma | COSMIC cancer mutations | soft_tissue-fibrous_tissue_and_uncertain_origin-synovial_sarcoma | 89 | 20 | 17385 | 2587 |
SGCE,EWSR1,NRAS,TRIP12,NF1,SF3B1,GORASP2,KRAS,OGDH,KCNQ1,DHX57,RB1,DNAJC10,PTEN,ETV6,STK11,FUS,TRAF5,HRAS,CDKN2A |
| 3.600e-02 | -3.32 | HAD_sf | interpro domains | IPR023214 | 67 | 16 | 18492 | 2768 |
CMAS,CTDP1,ATP13A1,ATP2C1,EPHX2,UBLCP1,PDXP,ATP1A1,ATP2A2,NT5DC1,NT5C3B,ATP13A3,NANP,CTDSP2,HDHD2,TIMM50 |
| 3.601e-02 | -3.32 | positive regulation of Wnt signaling pathway | biological process | GO:0030177 | 176 | 36 | 17256 | 2622 |
ZBED3,XIAP,CSNK2A1,SMARCA4,PSMD9,CDC73,PSMD2,PSMA6,PSMD1,MBD2,PIN1,AXIN2,ZRANB1,DVL2,USP34,PSMA8,ASPM,PSMB7,PSMA1,SOX4,MACF1,PSMB9,PSMB3,DAPK3,PSMC4,HHEX,RPS27A,PSMD8,PSMD3,AXIN1,ARNTL,ATP6V0C,RBPJ,DVL1,PSMC1,CSNK1D |
| 3.601e-02 | -3.32 | negative regulation of DNA metabolic process | biological process | GO:0051053 | 131 | 28 | 17256 | 2622 |
DNAJC2,ERCC1,TRIP12,THOC1,HELB,GTPBP4,CDC6,BLM,MEN1,TTF1,TRIM28,XRCC5,TERF2IP,CYREN,SMC3,KLHL15,PARPBP,MSH2,TIMELESS,CHEK2,ZNF830,POT1,TERF1,OGG1,MSH6,RNF169,TERF2,POLQ |
| 3.607e-02 | -3.32 | Diurnally Regulated Genes with Circadian Orthologs | WikiPathways | WP410 | 49 | 13 | 5312 | 837 |
UGP2,TAB2,ARNTL,ETV6,CRY2,NCKAP1,DNAJA1,DAZAP2,EIF4G2,PURA,TOB1,ZFR,CBX3 |
| 3.612e-02 | -3.32 | GO_DNA_MODIFICATION | MSigDB lists | GO_DNA_MODIFICATION | 77 | 18 | 17377 | 2626 |
HEMK1,DNMT3A,EXOSC6,BAZ2A,MTA2,EHMT1,CTCF,MPG,KDM1B,TRIM28,NEIL2,MBD4,GNAS,TET3,PRMT7,BEND3,DNMT1,OGG1 |
| 3.612e-02 | -3.32 | AGGGCCA,MIR-328 | MSigDB lists | AGGGCCA,MIR-328 | 77 | 18 | 17377 | 2626 |
MAX,DNMT3A,MECP2,SLC2A1,ARID5A,WDTC1,AGPAT1,UBE2Z,FAM133B,GSTCD,DPYSL3,SUGP1,SERTAD2,CSNK1G1,ETV6,H2AFX,ATXN2L,YWHAZ |
| 3.612e-02 | -3.32 | GO_POSITIVE_REGULATION_OF_GENE_EXPRESSION_EPIGENETIC | MSigDB lists | GO_POSITIVE_REGULATION_OF_GENE_EXPRESSION_EPIGENETIC | 77 | 18 | 17377 | 2626 |
KAT2A,POLR2L,POLR2K,SF3B1,WBP2,ARID1A,SLC50A1,ARID1B,TWISTNB,ATAD2,CD3EAP,BAZ1B,H2AFY,ACTB,POLR1B,H3F3A,ZNRD1,SMARCD1 |
| 3.617e-02 | -3.32 | other | COSMIC cancer mutations | other | 15297 | 2304 | 17385 | 2587 |
HECA,ZBTB10,ABCC10,HEXB,CCNL2,FBXO22,EEF2K,THAP4,RAD23B,ATP13A3,DNM2,FTSJ3,USP34,CCDC57,ERCC1,NRAS,EHMT1,KIF15,WDHD1,MIER2,DIDO1,RAB22A,SMAD2,MID1IP1,RPS27A,MYO18A,MPV17,COX5A,SMAD1,ANXA11,SLC25A33,ZNF720,SEC61G,GGA1,MUM1,CCZ1,TRIO,RAB23,KCTD17,HAUS4,EIF2AK4,APH1B,PARN,CDC73,MYL6B,ATG4A,TMEM179B,ERV3-1,SMC3,C4orf3,GEMIN4,MVP,NUP85,PPP6R1,PABPC1,NSUN4,PPA1,IFRD1,AGGF1,FOXK1,RBM42,GTPBP4,MAP7D1,MRPL16,ELK1,EIF4H,RDH11,KPNA1,ETS2,TYW5,WIPI2,RUFY3,PDLIM5,ACSF2,RHOG,EXOC3,VTI1A,INO80E,SLC35B2,RCOR3,LCLAT1,CPNE3,KIAA1147,RBM23,ZNF420,AHCTF1,TBC1D22A,TBC1D14,NSFL1C,SEPT11,GPD1L,ZC3H3,ARL5A,PDCL3,SNX8,ERMP1,IDH3A,POLR2D,MEF2D,TMEM147,GSTCD,TANC1,MAT2A,VPS26B,NSMCE2,CORO1C,CAMKMT,PPP5C,PITRM1,TUBB,COMMD10,ZNF445,HABP4,CCM2,FLOT1,BTN3A1,ATG2B,GOLM1,ZBTB45,HUWE1,NAA50,ANXA5,LTN1,UBE3B,NAP1L4,ZNF710,ST8SIA2,SPTAN1,STAU1,TCTEX1D2,DDX24,TACC1,MRS2,LDHA,HEBP2,LLPH,C14orf132,RAB3IP,TTC33,PICALM,SH3BP5,SLC19A1,ACOX1,FAM3C,AEN,PARP10,YWHAH,FAM129A,TRIM11,YTHDC2,SNX15,NENF,SND1,RUFY1,TRIM65,ZER1,PRNP,KRR1,RAB8A,NUP210,NT5DC1,NOC2L,EIF5,TACC3,VPS13B,RYBP,PTPN18,MIOS,SNRPB,MBLAC2,CDC6,PBRM1,ODC1,USP21,TRAM2,FBXO28,ARRDC1,ADAM9,DVL1,NUMB,ZNF564,C1orf74,CTU2,PARP12,CENPF,LAMTOR3,CHCHD2,NCKAP1,LYRM2,RSAD1,TNS3,SUB1,RINL,KIF13B,MBD2,XPA,AHCY,RBM3,GLE1,LRSAM1,HDHD2,NTPCR,NSDHL,AMD1,CAMSAP1,METTL22,ICAM2,STYXL1,APPL1,RXRB,SDHB,PCM1,GALNT2,TMEM168,NLRC5,BTBD10,MYO9A,CCNB2,USP7,GLT8D1,RPLP2,SUCLG1,ARID2,TMX4,SLC2A1,ATP6V1B2,PCBP1,LYN,VAV1,TMEM69,MRPL50,PSMA6,ZNF473,ZNF302,BRPF3,TARDBP,BCAP29,CTDSP2,PRPF19,PPIF,KDM3B,MND1,CLCN3,BIRC3,RAB7A,ANKRD33B,PPIE,CHMP2B,VDAC1,EIF3H,TMEM201,GLOD4,IDE,DHX16,UHRF2,XRCC3,CHMP4B,PARD3,BCL2L12,C19orf53,KLHL21,PDAP1,TMX3,CDCA8,GTF3A,SLC12A9,TUBGCP2,DNAJB9,HOMER1,WBP1L,POLR1B,RBM15B,PPAN,RHOA,RPRD1A,BTAF1,TOP3A,ARHGEF12,PCGF1,DDX23,RAB18,TRIM26,PDCD6,ATP6V1D,L3MBTL3,FAM110A,NEIL3,CTBS,BBX,IMPDH1,TAF12,NR2F2,HIPK3,IFI16,TXN,NUP188,H2AFZ,PNISR,PRKCSH,USP39,UBE2I,SLC25A37,ASPHD2,RAB4A,TRA2B,TAF5L,CISD2,ZNF800,CDC5L,ZNF524,SGCE,OSBP2,NSUN2,USP22,CLNS1A,EIF3A,ZMYM3,DOT1L,IWS1,ANKRD10,WAS,KIF18B,TPP2,ZMAT3,B4GALT2,PRPF38B,RECQL,C9orf78,EWSR1,RRM1,ACAP1,B4GALT1,FAM136A,SUPT7L,TMEM165,CNOT3,NPLOC4,SPAG5,WDR48,RTKN,CEP104,EXOSC7,KLHL5,LRRC8D,MSH2,PIGG,FBXL7,OSTF1,SYTL3,FAM171A1,APOL1,GCC2,PRIM2,ELL2,RDH10,MFNG,GORASP2,CAPZA2,ADRB2,CCT8,MTR,PHF6,SLCO4A1,TTC13,GOLGA2,RBMX,MED15,PIAS2,APPL2,SAMD8,NUDT3,CDKN2A,ZNF511,ATXN3,RAF1,KIAA0232,C2orf49,CD320,EPM2A,CCNA2,MTMR4,BRI3,TP53BP2,AQR,RBM12B,ILKAP,CDK12,SAP30,BRD4,DRAP1,NARF,LRRC8A,ELP4,ABHD11,PKMYT1,ASB13,TRIM28,SUPT16H,EIF3K,CHMP4A,CBWD1,ATF6,PRPF4B,ADAM23,NDUFS1,MECP2,SECISBP2,HMG20A,WWP2,SLC25A36,JAKMIP1,CCNK,DNAJC8,ELP5,AXIN2,CITED2,JMJD4,KAT2A,RABIF,ADSL,PACS1,BMS1,KCNQ1,OTUD3,ARSK,MACF1,KIF11,KLF6,SMAP2,FADD,SH3GLB1,MYO1F,CBX3,TMEM127,PPP1R11,DDX5,WDR62,TAF6,ESPL1,DDB1,DEF6,FAM83G,IPO4,UBL3,PIGM,NAT9,LYRM4,GPR132,UBE2Q1,PTP4A3,BRIX1,MRPL19,ZNF696,SF3B2,PCYOX1L,CDC42,SYNM,GOT2,JAZF1,HADHB,RPF2,SLC35C2,CNNM3,CARM1,SRPK2,WDR41,LARS,ZCCHC10,CCDC138,LRBA,TMEM216,SUMF2,KMT2C,OGFR,PRPSAP1,ASF1B,RPL37,MAN2A2,EIF4ENIF1,NIP7,U2SURP,MIA2,ZNF268,VPS4A,ATP6V0E1,PPP1R2,PM20D2,XPNPEP3,RGS2,LYAR,FAM89B,POLR2I,TRAFD1,SUGP2,GBA,EIF2A,SYVN1,CCDC71L,DAPK3,ARHGAP15,MASTL,UAP1,NFIL3,FN3KRP,YWHAZ,CTSA,TMEM14A,TSEN15,ADNP2,TCF12,PRKAB1,MDH2,SMARCA4,ORC1,RRN3,UBXN2A,IARS,KIF14,EXOSC1,CS,CLTB,DNAL4,CSTF1,POU2AF1,UBQLN4,NXT1,PGGT1B,SELPLG,SMU1,ATXN1,GLO1,OGDH,BICD2,CADM1,EDEM2,HERPUD2,TOLLIP,FANCE,MBD3,PDHX,RPS9,ALKBH6,SURF4,DUS3L,ARNTL,ANP32E,FKBP5,TMEM101,CCDC125,ABCA1,PDCD2L,GCLM,RAE1,DCTN2,NUP54,CHIC2,PAWR,MXD4,DCUN1D4,PIP4K2A,XPR1,FERMT3,KIF5B,KLHL20,SEC24C,RRBP1,ARHGEF2,ANP32A,LDLRAD3,C12orf75,STAT3,MYO5A,NIPAL3,TXNL1,DCAF6,FAM49B,TMEM39A,RFFL,COG1,RCOR1,PRMT2,TFEB,LEMD2,SERF1B,UPF1,ELMO1,ZC3H7B,DTX4,ZMIZ1,TERF1,HRAS,CCDC93,FGFR1OP,TMED7,PIGQ,CNTROB,PPP1R16B,GSDMB,TTC9C,PDS5B,NUP153,SENP1,PGAP2,TMEM115,PLEKHM3,DCUN1D5,PWWP2B,TRIM47,WDR11,AXIN1,SMG9,TRIM52,LONP2,NDUFV2,PHF23,CERK,SLC4A2,EZH1,ITGB5,LMNA,MCTS1,DDX56,EIF2S2,SLC38A5,FOXN2,CARS2,PRRC2A,C16orf72,RB1CC1,ZMYND11,PGS1,MYBL2,UHRF1BP1,MPG,MATR3,CYB5A,NCDN,SETD3,TEX30,PTAR1,CNOT6,NDE1,EGLN1,ZNF207,ANKRD27,PPP1R37,ABCA3,SARNP,IVNS1ABP,MON1B,NIT2,NUF2,ZNF267,TCF19,TMEM161B,KTN1,APP,PRKD3,CLUAP1,ATP2A2,UTP18,GRSF1,ZCCHC2,RNF19A,FAM76B,CLN6,TMEM9,GCC1,RNF169,ADCY7,ATP6V1G1,RNPS1,CDCA2,GPR137,DDX17,CHCHD3,PEX5,CDC16,HIPK2,MBOAT1,TICAM1,PDXK,ZBTB11,ANXA6,TMBIM4,GMCL1,UBE4A,IL21R,ETS1,WRB,ZNF92,PNO1,CAPN2,ADD3,SUV39H2,TTLL12,TMX1,HNRNPM,MFSD12,LDHB,PPP3CA,NUDT8,POLK,EMP3,MTMR12,ZP3,PDE3B,KIF18A,CCDC6,WNT5B,MAPK6,C4orf46,LY75,SLC25A19,RGL1,PSAP,WDR76,IGBP1,FAF1,SNAPIN,COX15,AGRN,THOC1,GNPDA1,GPBP1L1,PPP1R15B,CSNK2A1,GIT2,BIRC2,ATPAF1,DLG5,ABL2,XRCC2,ZFYVE27,MCMBP,PTPRK,CDC37,METTL1,HARS,GMFB,ESYT1,ANLN,RAB5B,RHEB,DPYSL3,TBC1D17,CDCA4,TONSL,NRM,NAGLU,ACTB,ZNF45,TMUB1,CTCF,ASAH1,DOCK11,CRLF3,LRRC14,NUS1,SLC27A4,MDFIC,MAML1,CYTH1,NQO2,UTP15,EIF2AK1,EIF4G2,ZDHHC3,MOSPD3,ITPRIPL1,CDC27,SNAP23,TBPL1,PRMT7,KCTD7,NDUFA5,CYLD,UGP2,COPE,HCFC1R1,ZADH2,GGPS1,RPAIN,RAD23A,ATP6V0B,PDK2,STRBP,DUS4L,MRPL34,PDCD2,SAP30L,SLC39A9,CLPTM1,DNAJC9,MTMR6,NFATC2,KDM1B,ARL5B,USP36,CCDC127,MRPL2,ATP1A1,PSMD3,CEP55,NDUFA11,DNAJC17,ZNF436,NCOA1,SLC25A39,ZC3HC1,ATXN7L2,CDC40,GOLIM4,RRP15,DAP,GNE,SMC6,ARFIP2,NKRF,BZW2,WRNIP1,TMA7,SS18L1,CENPM,PTGES3,CAMK2G,MLEC,ZNF202,PPWD1,RHOT2,NEU1,TPD52L2,GOLGA7,TWSG1,GLG1,PGRMC1,FAM126A,RPS6KC1,UBE2C,PPCS,NDUFB6,TMEM41B,ZDHHC8,PLXNA1,CCNB1,SLC20A1,COMMD6,ABHD14A,POLR3K,ASAP2,SNUPN,CNPY4,PLCL2,TFG,SEH1L,ATG9A,PBK,MKI67,DDX20,AMDHD2,SLC17A5,GALNT7,CCNF,FOXRED1,RBM47,PTER,WDR4,DHTKD1,TRAF5,HDAC2,PWWP2A,HSPH1,LIME1,MAPRE1,CHTF18,ADO,KIF23,SLC35B1,NOTCH2,PMF1,JMY,FKBP1A,SLC31A1,SNX18,ATIC,CTPS1,ATP6V0A2,PIKFYVE,RNF135,LPCAT1,EEF1D,TMED2,FTL,DDX28,PIP4K2C,FAM133B,RIT1,PLEC,KDM3A,SF3A2,FAS,EPRS,ZNF777,TMEM54,QARS,TCOF1,CABLES1,NRBP1,DNMT3A,RWDD1,CKLF,TRIP10,SF3B1,CAST,SUZ12,RPS6KA1,RAC1,GPR89A,OLA1,GNB2,FLAD1,APLP2,KDM2A,TNPO2,CDKN1B,TALDO1,GPX4,ATP13A1,MAPRE2,ERF,CUL3,SLBP,KIAA1586,H2AFV,GAR1,PSMB9,POLG2,DHX57,NSA2,HSPA4,MRPL55,JAK1,GOLGA8A,TBL3,SEL1L,H2AFX,KLHDC4,B4GALT3,PDCD11,ATMIN,POLQ,OTUD5,NCOR2,ANKRD13D,PKP4,SCAMP3,BABAM1,CDCA3,SLC25A12,BLM,TMCC3,GTF2F1,CRAT,AHSA1,PRC1,UPF2,COPS7B,SLC38A10,CNPY3,UBE2M,IFT46,TSHZ1,ZFP64,STRIP1,DENND4C,WDR18,ILF3,LRRC1,RHOT1,MARK2,TSR2,ECH1,PRDX1,PLD3,NUCB1,FBXO21,GNA12,C1orf131,PRDX3,PFDN4,HNRNPH3,TFDP1,STX18,KHSRP,ASNA1,SSSCA1,VPS29,BYSL,S100PBP,MIB2,PTMS,NOP2,UBN1,DCAF15,NF1,ALKBH5,UBE2Z,TAF6L,MAPK14,BECN1,SNAPC4,RNF103,BCAT2,MBD4,C18orf32,METTL14,ZNHIT6,IMPAD1,RCSD1,PHTF1,SRI,KIF22,ZBTB22,NFU1,OGG1,TRIM14,ELOF1,COPS8,FYTTD1,TRIM8,RRM2,ABHD5,UBTF,CXXC4,PAF1,SPATA2,PQBP1,IARS2,ATXN2L,GALNT10,STARD3NL,RPS15,PIGN,AGTRAP,CIB1,XPO7,SRRT,ZNF449,CAPZA1,GLTP,BCL2,KIFAP3,N4BP2,HP1BP3,VOPP1,THNSL1,ISG15,CAND1,GNAS,TSC1,RBM25,ZFP90,RBBP4,ZBTB24,SMARCD1,MBD1,WASF2,MMACHC,TOMM20,IFI27L1,GNPNAT1,MPHOSPH8,HNRNPUL2,CHD1,MEAF6,C2orf68,CCDC50,AKAP8,PARL,RPN2,CHTOP,F2R,FAM3A,TMEM14C,ABI1,HTRA2,MOSPD1,RLIM,FAM172A,ZNF500,PSMB7,NLN,WIPF1,BUD13,NDUFB1,PEF1,EIF3G,BTBD1,TAB2,TULP3,WDR59,CANT1,SCARB1,GAS2,USP11,SMURF1,TSPAN5,CDS2,MAGEH1,EYA1,MRPS26,LETMD1,KLF13,RGS1,HDDC2,MAN1A1,FBXO5,GART,TANK,PELO,BRD7,MRPL11,SAMD4B,ZDHHC18,GTF3C6,POLR3GL,WDR81,MEN1,ZNF407,MFN2,COX8A,MBD6,SRSF3,IDH3B,TATDN1,ATP6V1C1,TSC2,LACTB2,CMTM6,ZNF275,ANKRD39,RPL23A,CDKN2C,NAPG,USF1,DNAAF2,MECR,AP1M1,UPRT,CRY2,ECD,TIPARP,LRRC59,ANKRD9,RHBDD2,MGAT5,BAK1,ZNF559,RHOBTB3,GABPA,WBP1,NUTF2,ARF4,GINS4,KRIT1,BOLA3,AHNAK,RAD18,PDRG1,RNASEL,CHPF2,OAZ1,PDCD4,SMNDC1,NXT2,HIVEP3,KIAA0100,CLSPN,RHOC,DHX9,PDCD7,PSMD9,HAUS2,COPB2,TFAP4,CD59,RIMS3,MEGF8,EFTUD2,FBXO7,MRPL21,LUC7L2,EIF3L,MTA2,TYW1,USP10,ITM2A,SSR2,MTX1,SFXN5,FNTA,PDLIM1,TXNDC16,ZNF830,TMEM159,MRPL3,ALS2,TRIM41,NQO1,POC1A,ANK3,PTTG1,TPX2,TBC1D13,GLRX3,STMN1,REPS1,CBWD5,ABHD16A,FBXL6,SH3BP1,MTA1,UBA5,CLCN6,INTS12,RPRD1B,CPNE1,SEC61B,FAM118B,GOPC,E2F3,CIRBP,RPL38,CRNKL1,PFKFB3,GORAB,RAB1A,GIGYF1,TMEM184C,PPP2CA,KIF2A,CCDC14,LSM6,RNF38,SNRPG,DMWD,USP13,MZT1,ZFP91,TRMT6,IP6K2,WDR5,SLC25A43,PMVK,IFT27,NEIL2,RRP36,SRXN1,RPA2,PSMD2,CLIC4,PDCD10,CBWD2,COQ4,ITGB8,ARF5,ARHGEF1,FBXL19,GTF2H2,TTPAL,UTP20,MAGT1,CD81,TMEM131,WDR13,FANCI,PAPOLA,CREM,TET3,FANCL,GLIS2,IL6ST,INTS1,POP7,SLC44A1,MTPN,ASB6,PLK1,CELSR2,SEPT9,RBX1,APH1A,CKAP2L,PSMG1,EAF2,IL12RB1,KRTCAP2,LUC7L,LSG1,NECAP2,ALG3,TRIM4,AGPAT2,CHD3,ZNF367,PRPF4,KPNA2,BEND6,CLN3,DNAJC30,FAM208A,NGLY1,POT1,CCDC137,RMND5A,HJURP,PHB2,DNAJB2,FAM53C,NKD2,SDC2,KLC1,CDK13,ADCK5,COX4I1,DNAJB1,RAB6A,ARID1B,C1GALT1,MLX,UBE2Q2,CCP110,ZNF746,ARL6IP1,CTR9,NIPSNAP1,ABHD2,DCAF8,ACSL3,LDB1,MAP4K3,RBM38,NMT2,IRF5,HAUS8,MBIP,ORMDL2,COX7A2L,ZDHHC7,SIL1,DTD1,UNC13C,SART1,TRAF7,NDUFAF2,TOR1AIP1,LAGE3,TM9SF3,ZFYVE21,RRAGC,OIP5,NRF1,WDR44,PPME1,EFCAB11,RPAP1,CABLES2,LMAN1,AHCYL1,TOP1MT,STRAP,SPSB3,ZNF583,SNX25,POLR2G,KIAA0040,ZNF780B,PPT1,NUP155,DCLRE1C,MRPS14,RHBDF2,SUGP1,RBL1,FASTK,UBXN2B,STK38,AP1S1,SLC22A23,H3F3A,CHID1,SMAD4,SLC30A9,CMAS,UNK,NADSYN1,HMGN3,NCAPG,SCYL2,FZD6,HERC3,GTPBP3,CTSS,ORC3,RNLS,YTHDC1,ACP2,HMGN5,CSRP1,ABCF2,TUFM,RANGAP1,PNPLA8,HAGH,API5,ZFR,SEC23IP,E2F1,TMEM219,USP20,RBPJ,PDCD6IP,MAX,GXYLT1,LUZP1,ADAM10,CXXC1,TSC22D3,AP3M2,CUL1,GYG1,NANS,OAT,MYEF2,ANKRD26,NOL11,FIZ1,ZNF200,MARCH2,SLC26A2,SRP72,KLF10,LACTB,CBFB,RFC2,RAB2B,PRIM1,MAP3K4,HHEX,LUC7L3,RPS14,MAP4,BTF3,PTPDC1,NMD3,PTOV1,DNAJC5,SCOC,DHPS,POLR2K,ANKH,VAV2,PRKAA1,C16orf87,GSPT2,TATDN3,DLGAP4,PXMP2,PSEN1,ZNF79,PDXDC1,VPS25,NDUFS7,YY1AP1,C12orf10,FAM192A,RPN1,LHX8,ARPC5,ZNRF2,TPST1,DAPK1,PIK3IP1,CYC1,SOCS5,FDFT1,PIGT,EMB,ZNF574,C1orf35,EXOSC9,ARID1A,PTTG1IP,C9orf40,FXR1,GOSR1,MAP2K2,TWISTNB,AKAP1,XRCC5,HMGN2,PI4K2A,CAT,DERL1,HSPBP1,ARAP1,USP32,FAM83D,CABIN1,SMPD4,GPI,CYTIP,TP53RK,RAB11B,UROD,SLC39A13,BCL2L1,NUDT19,DECR1,RALB,ADCY9,LPIN2,MRPS27,SOCS6,TTC3,RNASEH2A,ANKLE2,CDC123,OAF,VDAC2,EDF1,EML4,ERC1,AMZ2,ANKZF1,RAD51C,ZNF282,DSN1,DDOST,HINT1,DGCR8,SAFB,HAGHL,RWDD4,LMBR1,NCLN,BEND3,EYA2,DYNC1LI2,MANBA,B4GALT5,SLC41A1,FAM76A,TKT,CBLL1,ARGLU1,LANCL1,POFUT1,FAM8A1,HEATR5B,HLA-A,EBP,RFWD3,NDUFA2,FJX1,FUT8,BTF3L4,PTPN11,MRPL54,FEM1B,RPL19,CNN2,NDUFA3,MTX2,MSH6,PDLIM2,LONRF3,RFXANK,FBXO9,GUF1,RPL32,ZHX1,OAZ2,NDUFS5,WDR91,POLA2,ZNF76,MTX3,COPA,UQCR10,PHRF1,HMGXB3,ABCB10,COMMD5,MAP1LC3B,DST,RAB35,SIVA1,GPATCH1,TCEA1,DEAF1,SNRNP200,LAP3,NCK1,VHL,SREK1,ARHGDIB,PITPNB,HSPB11,BRWD1,PPM1G,SH3GLB2,BAZ1B,ACBD4,STK11,CLU,CHEK2,ZSWIM3,TSTD2,MRPL13,CHPT1,DCAF5,CAPN1,UBE2D3,NSMCE4A,PPP1R12A,ZCCHC8,GORASP1,PCSK7,EPN1,THRAP3,QSOX2,TTF1,NUP205,PRPF18,CHKA,DTL,MED10,ZRANB1,SLC12A2,ATP6V0D1,CSNK1G3,CREG1,NUDT4,VKORC1,SLTM,EVC2,KLHL15,SIAH2,SLC16A1,EHD4,SNRNP70,APOL2,N4BP2L2,CHMP2A,CORO7,FEZ2,UCK2,PMS2,CLCC1,EXT2,MXD1,USP5,HNRNPA2B1,NVL,CYB5R1,ZNF770,EBAG9,RNF25,PCGF6,PON2,HNRNPR,STAT6,HPS5,MAPK1,BRD9,TMEM33,NAT14,DNAJC2,TRIP12,SCYL1,VPS45,MYO9B,GFM2,SPPL2A,FASTKD3,FGFR3,MZT2A,PPIG,ZDHHC13,TMEM99,H2AFY,NDUFS8,ATG13,ERI3,FBL,SLC35A1,FRMD8,MICAL3,TGFB1,ELOVL5,HEMK1,TIMMDC1,HELB,PSPC1,SCFD2,NDRG3,CDK11A,MEGF9,ACAT1,CENPT,PLOD3,RAB3IL1,ZSWIM6,RAB14,ADD1,KDM4A,MRPS15,XIAP,DHX8,GLUD1,ANKRD23,PABPC4,CDK5,CALM2,PSMD1,NSRP1,RABGAP1L,SRSF4,FNIP2,KCNAB2,PCBP2,PLK3,ZNF672,MRPL43,MCL1,PPFIA3,SMC2,ICMT,LIMK1,ZNF689,PRDX5,ATE1,MLYCD,ST3GAL2,ATP6V0C,FBXL3,E2F2,PFKP,AAAS,DDX42,SSRP1,MRPS2,STRN4,TOP2B,ZNRF3,TMED3,DDRGK1,RAVER2,GNS,INTS7,INPP5A,MCM5,PHF14,ZNF326,UBE2QL1,NAGPA,TSPYL4,DHX29,TEX10,MAN1B1,RPS10,CBFA2T2,ABCF1,RHOB,LRRC14B,DTWD1,PTPRF,SCARB2,OSBPL11,CCDC86,DUSP3,HEXA,RNF139,SNX14,TRERF1,UBR2,CHD1L,ACTR3,WDTC1,MYH9,CREBL2,NIPA2,PRKACA,SAFB2,ANKIB1,STAM,ARL6IP6,RAB21,SP100,ZKSCAN1,DDA1,NUP107,ANKRD13C,MAVS,CEP63,ATF2,RBM15,DCTN1,SHOC2,PSRC1,MAP4K4,WBP2,ATP6V0A1,NUSAP1,NDUFA7,DNAJA1,TAF2,C19orf54,SEC61A1,WDR7,CBLN2,FUS,LRP8,COIL,LRCH1,GALK1,ZNF786,RPS2,SESTD1,TRAK1,SIKE1,AKT1S1,KRI1,FBXO3,ERH,GATC,NDUFB4,PPP1R8,PRDM4,GTSE1,GEMIN6,DCP1A,SGCB,IMPA2,NUDC,PDPK1,TK1,TNFAIP3,GALC,ZNF512,KIAA0930,MRPS10,DDX39A,RPA1,ZNF862,ZNF180,KEAP1,POLE,TATDN2,PITX1,CAPN7,LRPPRC,PML,HMGB2,USF2,ANAPC4,SRM,DDX47,MCCC1,CDC42SE2,S1PR2,CDIPT,SEC16A,SSR1,LIN9,PCNA,ZNF639,TRMU,ETV6,PIK3R2,TXLNA,PPCDC,FAM86C1,MYBL1,CCAR1,MRPL32,ABCC5,BAZ2A,PBXIP1,TLK1,MRPL12,EZR,LNX2,LRP5,BRCA1,PRKRA,STX16,EPB41,OPTN,SEPT1,SOCS4,QRSL1,PIEZO1,OSGEPL1,GLCCI1,NUDT11,NAA60,SEPHS2,LZTR1,RACGAP1,PPP3CB,B4GALT4,RLF,RAPGEF6,SNRNP25,RB1,VASP,VMP1,MEA1,TIMELESS,AHDC1,ALDH18A1,TMEM8A,PREB,ABCC1,TRAPPC9,AACS,MEMO1,KRAS,UBE4B,NFATC2IP,LY6E,ARPC1A,ZNF174,PSMC4,GOLGA4,PALB2,SYNCRIP,PRPS2,NIPA1,TIGD2,RNF114,FOXM1,MRPL39,XAB2,SUMO2,DUSP22,COMMD8,RPL11,CSDE1,MDM2,CORO1A,METTL9,MINPP1,POC5,DVL2,GM2A,PSMA8,COQ10B,CPOX,TIGD5,SLC26A6,CYP20A1,PRPF3,TXNL4A,RPSA,SRSF1,DNAJC10,ZNF700,SCAP,TIMM17A,TOMM6,LTA4H,AP2S1,USP53,INTS2,CTDP1,MIF4GD,CDT1,ARID5A,SUMF1,GGA2,CSNK1A1,AP3S1,RMI1,TFRC,PTPN2,IRF4,STARD9,NDUFV1,SLC1A4,CWC27,SLC35B4,DDX31,ABCD1,RPAP3,CNTN5,SNX2,ZMYM5,CCDC34,CHCHD6,BSDC1,FBXO41,KPNA4,BIRC5,TFE3,SNAP29,CDCA7L,PKD2,CHMP7,SAT2,GCSH,ZNF496,TMEM109,TAP1,YTHDF3,NHLRC3,IKBIP,ELMOD2,KIFC1,DBNDD1,CYB5RL,PARPBP,CDC25B,PRADC1,DNMT1,NOL12,ORAI2,AKT2,NOL8,GNG7,AURKB,MCFD2,SLC25A5,ZFAND5,MAK16,STT3A,TMED10,PSMD8,EIF2D,ITGB1,UQCRH,RRS1,ARRB2,RTN3,ZNF598,DDX58,WSB2,PPIB,MUT,GMFG,HLA-E,NDUFA4,MAN2B1,METTL3,CFLAR,NDUFS4,RNF121,MEX3C,KLF16,HDAC7,DAD1,BDH1,PCYT2,GNAI2,ANKHD1,MORC3,TERF2,KCTD20,SEPT8,DCTD,PKM,TOMM40,PATL1,ADSS,SERF2,ZFP92,NSF,DCK,ERGIC3,ACLY,LPCAT4,VCPIP1,PPP6R2,MAP3K5,YY1,CDK2,RNF14,ZC3HAV1,SYS1,ZBTB37,URB2,EIF3D,MAGED1,KLHL18,ADPGK,SLC25A44,AP1B1,SDHA,PAIP2,PHC2,CRKL,TERF2IP,CYHR1,ZNF75D,SHC1,UCHL5,NAA35,TMBIM1,CCT2,MKLN1,LYRM1,GALK2,CDC23,SHCBP1,AP4E1,PRDM11,VEZF1,PPP2R5A,ACYP1,STAT1,PPA2,TRIM32,RHEBL1,C1orf112,TCF3,MRI1,BRAP,AGPAT3,MYNN,SPR,RAB11A,REEP5,FOXO3,MAD2L2,CCDC28A,RBM17,MAT2B,PTEN,CENPJ,OSTC,CREB1,NCOA2,PACS2,SMC4,NEK7,NET1,PARP4,TBRG4,ANAPC2,YIF1A,SGSH,HGS,TTLL4,SLC38A7,MFAP1,CCDC69,BRWD3,ESYT2,SKA3,NPHP4,UBE2E2,HNRNPAB,PLXNC1,TMEM184B,ST13,DNAJC24,ZNF107,SLC29A1,KIF2C,AGFG1,SIRT2,USP48,SNRPD3,UBQLN2,FKBP2,CUTC,EDC3,UBLCP1,ZNF804A,RAP1A,THADA,EIF4A3,AP3S2,ATG3,DPYSL2,PPP1R12C,AKR1B1,JOSD1,NDUFB9,RP2,TTC4,TECR,ARID4A,FGFR1OP2,TIMM50,TDP1,DPM1,FOPNL,SLC16A7,SLC25A22,STK17B,DHX15,CHAF1A,GEMIN5,COPS6,SASS6,PSMC1,SLC12A7,TBC1D12,MED13L,TIA1,MEF2A,EPHX2,PITHD1,RHBDD1,BANF1,ZNF335,BUD31,YBX1,KNTC1,UBE3C,ACAD8,ZNF189,ALDH9A1,KDELR1,TSTA3,CIC,OXR1,SEPT7,NAP1L1,ODF2,EXOC4,NUP62,PITPNA,KIAA1328,NAA20,PTDSS1,PDSS2,C7orf26,TMEM106C,IMMT,ASH1L,CHERP,WDYHV1,PLAGL2,IRF3,CHKB,TWF2,PAIP1,ANKRD28,FARSA,ANKLE1,SAR1A,SCAMP4,APOOL,PDIA6,ACSL5,TOR1AIP2,AZI2,GFER,RAD54B,TMEM41A,DAP3,ZNF317,GADD45B,AKNA,REEP4,CBX4,KIF3B,GOLPH3L,SH2D3A,CASP6,TOR3A,SRGN,DBF4,SAC3D1,CTNNBL1,CLDND1,TTC17,SLC25A1,GINS1,PAQR6,CSNK1G2,TELO2,HMGN1,ADAM17,NASP,ASPM,PPP1R21,PRKAR1B,SYMPK,TARS,SNRPA,MAPK3,HSPA1B,HLA-B,PLAA,ATAD2,ZNF330,OSBPL8,KBTBD7,PREPL |
| 3.618e-02 | -3.32 | human chr12q24.11 | chromosome location | human chr12q24.11 | 43 | 9 | 26185 | 2809 |
FAM216A,ATP2A2,SELPLG,CORO1C,ANAPC7,GLTP,UBE3B,GIT2,VPS29 |
| 3.618e-02 | -3.32 | GSE21546_WT_VS_SAP1A_KO_DP_THYMOCYTES_UP | MSigDB lists | GSE21546_WT_VS_SAP1A_KO_DP_THYMOCYTES_UP | 177 | 36 | 17377 | 2626 |
DDX58,CYLD,PARP12,TRERF1,AGTRAP,HLA-E,TAP1,BTN3A1,BIRC2,ANKIB1,EIF2S2,TAP2,TRIM14,SNX25,ABHD2,LAP3,PFKFB3,UHRF1BP1,DNAJA1,PRPF3,OGFR,PSMB9,PATL1,ISG15,OPTN,HLA-B,VEZF1,TRIM26,CSNK1G1,NLRC5,PML,STAT1,EHD4,APOL2,IFI16,ZC3HAV1 |
| 3.618e-02 | -3.32 | GO_REGULATION_OF_PROTEIN_IMPORT | MSigDB lists | GO_REGULATION_OF_PROTEIN_IMPORT | 177 | 36 | 17377 | 2626 |
DDX58,CYLD,TXN,CHERP,NF1,NUP54,RAB23,PPP3CB,MAPK14,PIK3R2,SRI,AXIN2,FAM89B,MDFIC,MAVS,OGG1,HNRNPM,TGFB1,PPP3CA,RHOA,NUTF2,BRCA1,TRIM28,PRDX1,AKAP1,KPNA1,KEAP1,TONSL,AXIN1,PPP3R1,NUP62,PKD2,ZNF268,PARP10,SMAD4,FAF1 |
| 3.618e-02 | -3.32 | GPR21 (G protein-coupled receptor 21) | protein interactions | 2844 | 72 | 18 | 17029 | 2761 |
SLC12A7,PIGN,ERMP1,TMEM184B,GPR89A,HSDL1,SLC4A2,SLC29A1,ATP5F1B,SLC12A9,LCLAT1,EBP,TMEM179B,CERS6,ADCY9,MIA2,LMBR1,TCEA1 |
| 3.618e-02 | -3.32 | Tmed10 (transmembrane p24 trafficking protein 10) | protein interactions | 68581 | 72 | 18 | 17029 | 2761 |
YTHDC1,TMED7,LUZP1,RB1CC1,ANK3,UHRF1BP1,TMED3,AP3S1,SRRT,STOML2,RPL37,DAP3,ATP6V1D,DGCR8,NDUFS8,HMGB2,TMED2,SPTAN1 |
| 3.618e-02 | -3.32 | APPL1 (adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1) | protein interactions | 26060 | 72 | 18 | 17029 | 2761 |
AKT2,MTA2,INO80E,APPL1,PLEKHF2,RAB21,BRWD1,PIK3R2,APPL2,SOCS6,RTCB,TTC4,RUVBL2,RBBP4,CLTB,ZNF830,HDAC2,RHEBL1 |
| 3.618e-02 | -3.32 | NEK6 (NIMA related kinase 6) | protein interactions | 10783 | 72 | 18 | 17029 | 2761 |
FAM208B,NEK7,DYNLL1,XIAP,EML4,FANCI,PSMD2,SMC3,CDC42,NEK6,PRDX3,PIN1,LRPPRC,RUVBL2,SMAD4,IPO4,KDELR1,CDC37 |
| 3.623e-02 | -3.32 | PPP3CA (protein phosphatase 3 catalytic subunit alpha) | protein interactions | 5530 | 77 | 19 | 17029 | 2761 |
PPP3CA,NASP,RHOC,MRI1,ARMT1,ADRB2,NCAPG,PSMD9,FKBP1A,MAT2B,PFDN5,PSMA6,PTEN,PPP3R1,TNPO3,FAM122A,BCL2,CABIN1,PDIA6 |
| 3.623e-02 | -3.32 | POC5 (POC5 centriolar protein) | protein interactions | 134359 | 77 | 19 | 17029 | 2761 |
DDX47,CCDC138,POC1A,HAUS4,MCM2,PRKACA,HAUS2,TFRC,HAUS8,RAB8A,PCM1,DDOST,CCDC14,IARS2,CHTOP,TALDO1,TTLL12,IDH3B,GM2A |
| 3.629e-02 | -3.32 | SARRIO_EPITHELIAL_MESENCHYMAL_TRANSITION_DN | MSigDB lists | SARRIO_EPITHELIAL_MESENCHYMAL_TRANSITION_DN | 143 | 30 | 17377 | 2626 |
C1orf74,TNFAIP3,BIRC3,CREG1,NCK1,HLA-E,TSC22D3,TCF3,GADD45G,ANK3,TKT,GLUD1,SND1,RGS2,KLF6,DLG5,DST,RPL37,PTEN,NFIL3,RPLP1,DAPK1,PSAP,CLU,MAP3K5,MVP,CITED2,STAT3,CCNB2,IFI16 |
| 3.629e-02 | -3.32 | GSE12839_CTRL_VS_IL12_TREATED_PBMC_UP | MSigDB lists | GSE12839_CTRL_VS_IL12_TREATED_PBMC_UP | 143 | 30 | 17377 | 2626 |
MIF,EXOC3,SARNP,PRIM2,ZCCHC8,DBF4,SSR2,NUP155,MRPL16,GORASP2,BRCA1,SND1,BLM,ANLN,SHCBP1,HAUS2,CLNS1A,DDOST,CCDC50,RBL1,UTP18,MEA1,SLC25A19,SMPD4,GEMIN4,LMAN1,CLTB,TFG,SLC25A33,TMED2 |
| 3.629e-02 | -3.32 | GSE21033_CTRL_VS_POLYIC_STIM_DC_6H_DN | MSigDB lists | GSE21033_CTRL_VS_POLYIC_STIM_DC_6H_DN | 143 | 30 | 17377 | 2626 |
PDPK1,TTPAL,KDM3B,TRAPPC9,ARID2,URB2,PRKDC,DENND1B,VAV2,ATP2C1,AP3M2,SMARCA4,COG1,CDK13,IP6K2,OTUD3,AZI2,SUPT7L,ASXL2,SLTM,PI4K2A,GPS2,AXIN1,WNT5B,MEGF8,FUT8,OGT,PIAS2,AFF1,TMEM131 |
| 3.629e-02 | -3.32 | MODULE_206 | MSigDB lists | MODULE_206 | 143 | 30 | 17377 | 2626 |
PHF20L1,GUK1,MRPL42,NET1,SUZ12,TRIO,USP10,SLC25A12,PTP4A3,BCLAF1,ARID1A,RAB3IP,UBE4A,MCM2,BRIX1,PRPSAP1,STK17B,RPAIN,EBP,HERC3,LSM6,SEC24C,ATXN2L,NAA50,PIGG,UBE3C,RNF135,B4GALT3,SAP30L,MORC3 |
| 3.638e-02 | -3.31 | Cyclophilin-like_dom_sf | interpro domains | IPR029000 | 22 | 7 | 18492 | 2768 |
PPIF,PPIB,PPWD1,CWC27,PPIG,PPIE,PPIL2 |
| 3.638e-02 | -3.31 | Cyclophilin-type_PPIase_dom | interpro domains | IPR002130 | 22 | 7 | 18492 | 2768 |
PPIF,PPIB,PPWD1,CWC27,PPIG,PPIE,PPIL2 |
| 3.638e-02 | -3.31 | FAD binding | molecular function | GO:0071949 | 26 | 8 | 17224 | 2647 |
CRY2,MMACHC,CYB5R1,KDM1B,CYB5RL,NQO2,ACOX1,MICAL3 |
| 3.642e-02 | -3.31 | GSE17974_CTRL_VS_ACT_IL4_AND_ANTI_IL12_0.5H_CD4_TCELL_DN | MSigDB lists | GSE17974_CTRL_VS_ACT_IL4_AND_ANTI_IL12_0.5H_CD4_TCELL_DN | 160 | 33 | 17377 | 2626 |
CYTIP,IER2,ZBTB10,TP53RK,MRPL42,ADO,KLHL18,MYNN,CYCS,CHAC2,WRB,DNAJB9,CREM,SLC31A1,ZNF200,TIMELESS,MCPH1,PPAN,BIRC3,ANKRD37,ETV3,BTG2,CRNKL1,RABIF,PFKFB3,KIAA1586,PNPLA8,ARL5B,SRSF1,PWWP2B,MTHFD2,MLYCD,KPNA2 |
| 3.642e-02 | -3.31 | GSE22601_DOUBLE_NEGATIVE_VS_IMMATURE_CD4_SP_THYMOCYTE_DN | MSigDB lists | GSE22601_DOUBLE_NEGATIVE_VS_IMMATURE_CD4_SP_THYMOCYTE_DN | 160 | 33 | 17377 | 2626 |
FEZ2,DNAJB2,BABAM1,COPE,ARID5A,AKT1S1,FAM192A,CTSS,COQ4,ATG3,DUT,ATIC,FAM89B,FBXW2,ANP32A,DDX31,CORO1A,DVL2,EID1,BTG2,AKT2,AMD1,CAMSAP1,CIRBP,C9orf40,EVC2,AMZ2,BOLA3,DAP3,CCDC86,DDX5,CCNB2,BYSL |
| 3.647e-02 | -3.31 | pyrimidine-containing compound metabolic process | biological process | GO:0072527 | 82 | 19 | 17256 | 2622 |
TK1,UCK2,RRM1,UCK1,DCTD,HDDC2,NEIL2,MBD4,TET3,ERH,DUT,DCK,TBPL1,CTPS1,UPRT,SLC25A19,DHFR2,MAPK1,OGG1 |
| 3.655e-02 | -3.31 | negative regulation of proteasomal ubiquitin-dependent protein catabolic process | biological process | GO:0032435 | 31 | 9 | 17256 | 2622 |
USP7,SENP1,PBK,PARK7,UBXN1,RYBP,OGT,SVIP,RPL11 |
| 3.655e-02 | -3.31 | protein localization to microtubule cytoskeleton | biological process | GO:0072698 | 31 | 9 | 17256 | 2622 |
PCM1,MAPRE1,CCDC14,DCTN2,FAM83D,DVL1,MCPH1,SPAG5,CSNK1D |
| 3.655e-02 | -3.31 | termination of RNA polymerase I transcription | biological process | GO:0006363 | 31 | 9 | 17256 | 2622 |
UBTF,POLR2L,CD3EAP,POLR2K,POLR1B,GTF2H2,ZNRD1,TTF1,TWISTNB |
| 3.655e-02 | -3.31 | positive regulation of RNA splicing | biological process | GO:0033120 | 31 | 9 | 17256 | 2622 |
RBMX,HABP4,TRA2B,SRSF5,THRAP3,SNRNP70,POLR2A,PRPF19,SRSF1 |
| 3.660e-02 | -3.31 | YOSHIOKA_LIVER_CANCER_EARLY_RECURRENCE_UP | MSigDB lists | YOSHIOKA_LIVER_CANCER_EARLY_RECURRENCE_UP | 36 | 10 | 17377 | 2626 |
NFATC3,USO1,PEX5,DNAJC8,SNRPB,WDR13,TKT,NARF,NLRC5,BSDC1 |
| 3.660e-02 | -3.31 | GO_POSITIVE_REGULATION_OF_PROTEIN_ACETYLATION | MSigDB lists | GO_POSITIVE_REGULATION_OF_PROTEIN_ACETYLATION | 36 | 10 | 17377 | 2626 |
TERF2IP,TGFB1,KAT2A,WBP2,BRD7,RUVBL2,BRCA1,SOX4,SMAD4,MAPK3 |
| 3.660e-02 | -3.31 | REACTOME_PI3K_EVENTS_IN_ERBB4_SIGNALING | MSigDB lists | REACTOME_PI3K_EVENTS_IN_ERBB4_SIGNALING | 36 | 10 | 17377 | 2626 |
PDPK1,MDM2,TSC2,PTEN,AKT2,CDKN1B,AKT1S1,CREB1,FOXO3,MLST8 |
| 3.660e-02 | -3.31 | GO_TOXIN_TRANSPORT | MSigDB lists | GO_TOXIN_TRANSPORT | 36 | 10 | 17377 | 2626 |
CCT2,GGA1,DNAJC17,ATP6V0A1,MTMR12,ARID1A,DNAJA1,CCT8,MFSD10,COPB2 |
| 3.660e-02 | -3.31 | MODULE_149 | MSigDB lists | MODULE_149 | 36 | 10 | 17377 | 2626 |
SEC11A,EIF5A,SEC61A1,EIF3D,EIF4H,EIF4G2,PABPC1,EIF3G,EIF3H,EEF1D |
| 3.660e-02 | -3.31 | GO_POSTTRANSCRIPTIONAL_GENE_SILENCING | MSigDB lists | GO_POSTTRANSCRIPTIONAL_GENE_SILENCING | 36 | 10 | 17377 | 2626 |
HNRNPA2B1,SMAD2,DGCR8,CNOT6,SMAD1,PRKRA,STAT3,METTL3,SRRT,RBM4 |
| 3.660e-02 | -3.31 | GO_MODULATION_BY_VIRUS_OF_HOST_MORPHOLOGY_OR_PHYSIOLOGY | MSigDB lists | GO_MODULATION_BY_VIRUS_OF_HOST_MORPHOLOGY_OR_PHYSIOLOGY | 36 | 10 | 17377 | 2626 |
TGFB1,CCNK,KPNA4,KPNA1,HIPK2,KPNA2,EIF2AK4,BCL2L1,CPSF4,ZC3HAV1 |
| 3.660e-02 | -3.31 | REACTOME_APOPTOTIC_CLEAVAGE_OF_CELLULAR_PROTEINS | MSigDB lists | REACTOME_APOPTOTIC_CLEAVAGE_OF_CELLULAR_PROTEINS | 36 | 10 | 17377 | 2626 |
FNTA,ADD1,CASP6,PLEC,ROCK1,GAS2,BCAP31,BIRC2,LMNA,SPTAN1 |
| 3.660e-02 | -3.31 | REACTOME_TRANSCRIPTIONAL_ACTIVITY_OF_SMAD2_SMAD3_SMAD4_HETEROTRIMER | MSigDB lists | REACTOME_TRANSCRIPTIONAL_ACTIVITY_OF_SMAD2_SMAD3_SMAD4_HETEROTRIMER | 36 | 10 | 17377 | 2626 |
UBE2D3,CCNC,NCOR2,SMAD2,RBL1,RPS27A,E2F4,TFDP1,MEN1,SMAD4 |
| 3.660e-02 | -3.31 | GO_REGULATION_OF_ERYTHROCYTE_DIFFERENTIATION | MSigDB lists | GO_REGULATION_OF_ERYTHROCYTE_DIFFERENTIATION | 36 | 10 | 17377 | 2626 |
SMAP1,LDB1,KLF13,HMGB2,LYN,ETS1,MAPK14,SENP1,FOXO3,ISG15 |
| 3.660e-02 | -3.31 | GO_VIRION_ASSEMBLY | MSigDB lists | GO_VIRION_ASSEMBLY | 36 | 10 | 17377 | 2626 |
CHMP2A,CHMP4A,PDCD6IP,RPS27A,CHMP4B,VPS4A,RAB1A,CHMP2B,CHMP7,LRSAM1 |
| 3.660e-02 | -3.31 | BERNARD_PPAPDC1B_TARGETS_UP | MSigDB lists | BERNARD_PPAPDC1B_TARGETS_UP | 36 | 10 | 17377 | 2626 |
TULP3,DENND1B,U2SURP,ENSA,ANP32A,AGPAT3,SMURF1,DUSP22,ZMAT3,PIP4K2A |
| 3.663e-02 | -3.31 | KEAP1 (kelch like ECH associated protein 1) | protein interactions | 9817 | 118 | 27 | 17029 | 2761 |
PDCD6IP,RBX1,GABPA,NUDT4,WDR1,OXR1,CUL3,CDK13,BRCA1,CCNB1,MAP1LC3B,GAR1,APP,NEIL2,FERMT3,CAT,KEAP1,PALB2,CLU,ZRANB1,USP11,SASS6,MCMBP,NIPSNAP2,TERF1,MLST8,TMEM160 |
| 3.663e-02 | -3.31 | TPM2 (tropomyosin 2) | protein interactions | 7169 | 118 | 27 | 17029 | 2761 |
ADD1,AKT2,MYH9,COX4I1,EBNA1BP2,CAPZA2,ANLN,STMN1,STK17B,STAM,BCAP31,MAPK3,RPA1,SRXN1,SF3B2,RPA2,SUB1,GRK2,MYO18A,ACTB,RBPJ,AHCYL1,CDK2,PDLIM5,SINHCAF,CCAR1,DDB1 |
| 3.665e-02 | -3.31 | BARD1 signaling events | Pathway Interaction DB | bard1pathway | 29 | 10 | 2226 | 426 |
UBE2D3,FANCL,EWSR1,PCNA,PRKDC,BRCA1,FANCE,CDK2,XRCC5,CSTF1 |
| 3.665e-02 | -3.31 | Trk receptor signaling mediated by the MAPK pathway | Pathway Interaction DB | mapktrkpathway | 29 | 10 | 2226 | 426 |
CDK5,RAF1,RPS6KA1,RIT1,CREB1,ELK1,EHD4,MAPK14,MAPK1,MAPK3 |
| 3.666e-02 | -3.31 | MIDORIKAWA_AMPLIFIED_IN_LIVER_CANCER | MSigDB lists | MIDORIKAWA_AMPLIFIED_IN_LIVER_CANCER | 51 | 13 | 17377 | 2626 |
FASTKD3,CACNB1,RPL19,CAPZA2,SYNRG,ARHGAP23,PSMB3,PARD3,SSR1,CREM,CWC25,SOCS7,DDX52 |
| 3.666e-02 | -3.31 | GO_NEGATIVE_REGULATION_OF_DNA_REPLICATION | MSigDB lists | GO_NEGATIVE_REGULATION_OF_DNA_REPLICATION | 51 | 13 | 17377 | 2626 |
TGFB1,SMC3,PML,GTPBP4,CDC6,CHEK2,BLM,MEN1,ZNF830,TTF1,TERF1,POT1,TERF2 |
| 3.666e-02 | -3.31 | TONG_INTERACT_WITH_PTTG1 | MSigDB lists | TONG_INTERACT_WITH_PTTG1 | 51 | 13 | 17377 | 2626 |
PLK3,RPS15,TRIM41,DDX47,EIF2S2,C19orf53,TBPL1,RPS10,RPF2,LLPH,WDR5,RPS26,HMGN2 |
| 3.674e-02 | -3.30 | TFIID-class transcription factor binding | molecular function | GO:0001094 | 9 | 4 | 17224 | 2647 |
ERCC1,RUVBL2,FBL,ZNHIT6 |
| 3.674e-02 | -3.30 | DEAD/H-box RNA helicase binding | molecular function | GO:0017151 | 9 | 4 | 17224 | 2647 |
SMAD1,ETV3,POT1,AKAP8 |
| 3.674e-02 | -3.30 | aryl hydrocarbon receptor binding | molecular function | GO:0017162 | 9 | 4 | 17224 | 2647 |
NCOA1,TAF6,NCOA2,ARNTL |
| 3.674e-02 | -3.30 | type I transforming growth factor beta receptor binding | molecular function | GO:0034713 | 9 | 4 | 17224 | 2647 |
TGFB1,SNX25,FKBP1A,SMAD2 |
| 3.674e-02 | -3.30 | RNA 7-methylguanosine cap binding | molecular function | GO:0000340 | 9 | 4 | 17224 | 2647 |
GEMIN5,CYFIP1,CYFIP2,AGO2 |
| 3.674e-02 | -3.30 | cytidylyltransferase activity | molecular function | GO:0070567 | 9 | 4 | 17224 | 2647 |
CMAS,PCYT2,NANS,CDS2 |
| 3.674e-02 | -3.30 | double-stranded telomeric DNA binding | molecular function | GO:0003691 | 9 | 4 | 17224 | 2647 |
TERF1,PURA,TERF2,XRCC5 |
| 3.679e-02 | -3.30 | RAB4A (RAB4A, member RAS oncogene family) | protein interactions | 5867 | 43 | 12 | 17029 | 2761 |
KIF3B,GRIPAP1,PIN1,DYNLL1,RAB7A,IDH3A,ACTB,PTTG1IP,ZNF830,RUFY1,RAB2B,MAPK3 |
| 3.679e-02 | -3.30 | PUM1 (pumilio RNA binding family member 1) | protein interactions | 9698 | 43 | 12 | 17029 | 2761 |
TRIM11,LAGE3,ANXA5,ATXN1,AURKB,SMAD1,EIF5,SEC16A,EYA2,MATR3,CLNS1A,CAND1 |
| 3.679e-02 | -3.30 | GAA (glucosidase alpha, acid) | protein interactions | 2548 | 43 | 12 | 17029 | 2761 |
MAN2A2,ATP5IF1,MRPL9,SYNCRIP,TMEM39A,ILF3,LDHA,B4GALT1,DHFR2,GALNT7,CHID1,LDHB |
| 3.679e-02 | -3.30 | ELK1 (ELK1, ETS transcription factor) | protein interactions | 2002 | 43 | 12 | 17029 | 2761 |
MOB4,EWSR1,PIAS2,BRCA1,ELK1,UBE2I,MAPK14,MAPK1,APP,MAD2L2,MAPK3,STARD3NL |
| 3.679e-02 | -3.30 | SMARCA1 (SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1) | protein interactions | 6594 | 43 | 12 | 17029 | 2761 |
USF1,RPS2,MAX,RFXANK,BAZ1B,SMARCA4,NFATC2IP,RBPJ,RBBP4,ARID1B,IFI16,DEF6 |
| 3.679e-02 | -3.30 | RNF115 (ring finger protein 115) | protein interactions | 27246 | 43 | 12 | 17029 | 2761 |
UBE2D3,PFDN5,DNAJB2,RAB7A,H2AFX,UBE2I,DAZAP2,HRAS,APP,SSSCA1,KDELR1,RAD23A |
| 3.679e-02 | -3.30 | TPT1 (tumor protein, translationally-controlled 1) | protein interactions | 7178 | 43 | 12 | 17029 | 2761 |
PLK1,MDM2,ATP1A1,VHL,RPLP1,MSH2,MCL1,BCL2L1,CDK2,MCPH1,APP,EEF1D |
| 3.679e-02 | -3.30 | ARID1B (AT-rich interaction domain 1B) | protein interactions | 57492 | 43 | 12 | 17029 | 2761 |
SMAD2,RBX1,BCL7C,SMARCA4,KRAS,ARID1A,PCGF1,SMARCE1,EYA2,ARID1B,CAND1,SMARCD1 |
| 3.680e-02 | -3.30 | macromolecule glycosylation | biological process | GO:0043413 | 257 | 50 | 17256 | 2622 |
GXYLT1,GORASP1,B4GALT5,MOGS,TRAK1,B4GALT1,RXYLT1,SDF2L1,B4GALT4,TMEM165,PSEN1,POFUT1,EXT2,MAN1A1,TET3,RPN1,C1GALT1,NUS1,DAD1,FUT8,RPN2,LMAN1,SLC35C2,ST8SIA2,OSTC,MGAT5,B3GALT6,NAGPA,TMEM115,DPM1,MAN1B1,MFNG,SYVN1,GALNT7,MCFD2,KRTCAP2,SERP1,ALG3,MAN2A2,GALNT2,MAGT1,GOLGA2,DDOST,STT3A,OGT,ST3GAL2,GALNT10,PLOD3,B4GALT3,B4GALT2 |
| 3.680e-02 | -3.30 | protein glycosylation | biological process | GO:0006486 | 257 | 50 | 17256 | 2622 |
GXYLT1,GORASP1,B4GALT5,MOGS,TRAK1,B4GALT1,RXYLT1,SDF2L1,B4GALT4,TMEM165,PSEN1,POFUT1,EXT2,MAN1A1,TET3,RPN1,C1GALT1,NUS1,DAD1,FUT8,RPN2,LMAN1,SLC35C2,ST8SIA2,OSTC,MGAT5,B3GALT6,NAGPA,TMEM115,DPM1,MAN1B1,MFNG,SYVN1,GALNT7,MCFD2,KRTCAP2,SERP1,ALG3,MAN2A2,GALNT2,MAGT1,GOLGA2,DDOST,STT3A,OGT,ST3GAL2,GALNT10,PLOD3,B4GALT3,B4GALT2 |
| 3.690e-02 | -3.30 | GO_REGULATION_OF_CELL_GROWTH | MSigDB lists | GO_REGULATION_OF_CELL_GROWTH | 377 | 70 | 17377 | 2626 |
FGFR1OP,PLXNC1,FOXM1,ADAM10,RPS6KA1,TMEM97,CSNK2A1,SMARCA4,PLXNA1,TWF2,CD320,CDK5,CDKN2C,RAB21,CDC42,DPYSL2,ZNF639,PIN1,KIF14,DNM2,CDKN1B,MTPN,EBAG9,CDKN2AIP,PSRC1,PPT1,NOL8,EAF2,OGFR,PPP2CA,LIMK1,STK11,TRIM32,H3F3A,CHPT1,SMURF1,SMAD4,SLC25A33,DNAJC2,CTDP1,CIB1,IP6K2,CDK11B,CRLF3,RAB11A,TFRC,MAD2L2,MEGF8,PRDM4,EI24,H2AFY,BCL2,TGFB1,IFRD1,PPP1R9B,ADAM17,FOXK1,NET1,ANAPC2,EXOSC9,MACF1,NDRG3,CDK11A,GOLGA4,SERTAD2,LTBP4,PML,RUFY3,CDKN2A,ADNP2 |
| 3.692e-02 | -3.30 | protein C-terminus binding | molecular function | GO:0008022 | 152 | 32 | 17224 | 2647 |
USP7,ERCC1,MIF4GD,MAPRE1,PHB2,CENPF,AGO2,MKI67,EZR,ATXN1,TOP2B,PCGF1,EPB41,OPTN,XRCC5,DST,PPP2CA,AFDN,MID1IP1,SIAH1,PRDX3,CSK,BANF1,MSH2,VPS4A,CORO1A,XRCC4,HRAS,IFT46,PABPC1,COIL,TERF2 |
| 3.692e-02 | -3.30 | Purine metabolism | KEGG pathways | hsa00230 | 173 | 37 | 7161 | 1149 |
POLA2,ADA2,POLR2K,RRM1,POLR3K,GART,ATIC,ADCY9,POLR1B,ZNRD1,ADCY7,ENPP4,AMPD2,NTPCR,POLR2I,PRIM2,POLR2L,GUK1,POLR2G,POLR2D,POLR3GL,ADSL,RRM2,PKM,PDE3B,TWISTNB,POLR2A,PRIM1,ADSS,POLR2J,POLE,DCK,NT5C3B,GUCY1B1,PRPS2,IMPDH1,CANT1 |
| 3.692e-02 | -3.30 | Purine metabolism | KEGG pathways | ko00230 | 173 | 37 | 7161 | 1149 |
POLA2,ADA2,POLR2K,RRM1,POLR3K,GART,ATIC,ADCY9,POLR1B,ZNRD1,ADCY7,ENPP4,AMPD2,NTPCR,POLR2I,PRIM2,POLR2L,POLR2G,GUK1,POLR2D,ADSL,RRM2,POLR3GL,PKM,PDE3B,POLR2A,TWISTNB,PRIM1,ADSS,POLE,POLR2J,DCK,NT5C3B,GUCY1B1,PRPS2,IMPDH1,CANT1 |
| 3.693e-02 | -3.30 | GSE1925_CTRL_VS_24H_IFNG_STIM_MACROPHAGE_UP | MSigDB lists | GSE1925_CTRL_VS_24H_IFNG_STIM_MACROPHAGE_UP | 183 | 37 | 17377 | 2626 |
IER2,PRKAB1,SRGN,BABAM1,CDCA8,PRKACA,GIT2,RSAD1,RPL11,CALM2,GSTK1,RAB8A,NFATC3,NUP210,CTSS,FAM171A1,DCTN1,SPTAN1,CIRBP,TUBGCP5,RANGAP1,EIF2AK1,ESYT1,MBD3,SF3A2,ISG15,TMEM127,HGS,SCAP,APPL2,RPLP1,SRSF3,USP11,TAF6,IGBP1,MZT2B,FAF1 |
| 3.693e-02 | -3.30 | GSE27786_CD4_VS_CD8_TCELL_DN | MSigDB lists | GSE27786_CD4_VS_CD8_TCELL_DN | 183 | 37 | 17377 | 2626 |
MIF,PPP1R37,PKP4,KIAA0100,SNX15,STRN4,DUSP22,C19orf48,TUBGCP2,TFRC,LRRC14,PDXP,UCHL5,MECR,H2AFY,OSTF1,ILKAP,EIF3L,KAT2A,SMU1,EZR,GSTCD,PDE3B,RPS9,CLNS1A,SMAP2,XRCC5,CHCHD3,ATP1A1,HSPBP1,KEAP1,SCAP,APPL2,TRIM32,HDAC2,IPO4,TUBB |
| 3.693e-02 | -3.30 | GSE20198_UNTREATED_VS_IFNA_TREATED_ACT_CD4_TCELL_UP | MSigDB lists | GSE20198_UNTREATED_VS_IFNA_TREATED_ACT_CD4_TCELL_UP | 183 | 37 | 17377 | 2626 |
MIB2,USP7,FEZ2,TRIP12,CKLF,CAST,ARID5A,TMX3,TBC1D13,EZH1,CAPN2,PDXP,TNS3,NDUFV1,SHC1,PPP1R8,CRAT,CDC25B,ALDH18A1,ST8SIA2,CPNE1,YTHDC1,ULK3,RBM42,PLEKHM3,EIF2AK1,RAB3IP,CBFA2T2,NDRG3,TRAM2,ZNF777,STAT1,DDX5,ARHGAP23,ACSF2,CHID1,NAA60 |
| 3.693e-02 | -3.30 | GSE11924_TH1_VS_TH2_CD4_TCELL_DN | MSigDB lists | GSE11924_TH1_VS_TH2_CD4_TCELL_DN | 183 | 37 | 17377 | 2626 |
GOLPH3L,FLYWCH2,ANKH,TRIO,SDF2L1,OAT,PSEN1,NUS1,RALB,ZNF260,AFF1,SLC38A10,MVP,TFG,SLC12A2,DRAM2,FYTTD1,SNX2,BTAF1,ERLIN1,MTMR6,ITM2A,MAP4K3,IL12RB1,MCFD2,RAB1A,VKORC1,TAZ,ARF4,TMEM168,HIPK2,OAZ2,PRDX5,SLC25A19,ATP6V0E1,NUMB,HIGD2A |
| 3.693e-02 | -3.30 | GSE14308_TH2_VS_TH17_DN | MSigDB lists | GSE14308_TH2_VS_TH17_DN | 183 | 37 | 17377 | 2626 |
CXXC1,TCF3,XIAP,ACAP1,SNN,ETS1,PITHD1,SDHA,RPAIN,DDRGK1,DNAJC8,RPL17,IL6ST,PARL,RNF19A,IFT46,ATP6V0D1,ANKLE2,ANKRD37,TACC1,METTL5,GLO1,WDR81,NDUFA7,PCGF1,TAZ,TTC33,POLR2A,EIF4ENIF1,JAK1,PML,DCAF11,CANT1,GPI,NCOA1,AKNA,ZBTB24 |
| 3.693e-02 | -3.30 | GSE369_PRE_VS_POST_IL6_INJECTION_IFNG_KO_LIVER_UP | MSigDB lists | GSE369_PRE_VS_POST_IL6_INJECTION_IFNG_KO_LIVER_UP | 183 | 37 | 17377 | 2626 |
POLR2K,PTTG1,YTHDC2,PTP4A3,MAN2B1,CDK11B,AP3S1,C19orf48,SPPL2A,WWP2,TET3,ARPC5,GMEB1,CORO1A,GPD1L,DNMT1,NOL12,METTL1,RHOA,PSPC1,EMP3,PRDX1,MAPK3,MYO1F,EIF4ENIF1,C1orf131,AHNAK,CDKN2AIPNL,ERGIC3,C1orf109,HAGHL,RBMS1,CTSA,KLHDC4,SMAD1,EYA2,DEF6 |
| 3.693e-02 | -3.30 | GSE22886_DAY0_VS_DAY7_MONOCYTE_IN_CULTURE_UP | MSigDB lists | GSE22886_DAY0_VS_DAY7_MONOCYTE_IN_CULTURE_UP | 183 | 37 | 17377 | 2626 |
IER2,PNISR,TSC22D3,KLF13,BTN3A1,ARGLU1,SECISBP2,CHKB,NOTCH2,EZH1,DAZAP2,RGS2,DUSP22,CRLF3,LYN,CHD1,WDR48,TET3,INPP5A,LPCAT1,SPSB3,AMPD2,KIAA0040,MCL1,SRSF5,ICAM2,KLF6,RXRB,MYO1F,MTMR3,WAS,MID1IP1,GADD45B,HMGB2,FAU,NDE1,PDCD4 |
| 3.693e-02 | -3.30 | GSE26890_CXCR1_NEG_VS_POS_EFFECTOR_CD8_TCELL_UP | MSigDB lists | GSE26890_CXCR1_NEG_VS_POS_EFFECTOR_CD8_TCELL_UP | 183 | 37 | 17377 | 2626 |
DDX58,COX15,PARP12,AGRN,HLA-E,FAM129A,TOR3A,HMGN3,NIT2,LYN,CNOT3,CSDE1,CLDND1,PTGES3,CNOT6L,SGCB,PABPC1,PPA1,FDFT1,ANKLE2,TRAFD1,MLEC,RNPS1,ASB13,AP4E1,ISG15,UBXN2B,EXOC4,STAT1,NLRC5,PML,KHSRP,VCPIP1,MRFAP1L1,RNASEL,NAA20,PURA |
| 3.693e-02 | -3.30 | Hedgehog 'off' state | REACTOME pathways | R-HSA-5610787 | 101 | 24 | 10287 | 1696 |
PSMA8,RBX1,PRKAR1B,PSMB7,PSMA1,CUL1,CSNK1A1,PRKACA,PSMD9,PSMB9,PSMB3,PSMC4,GNAS,PSMD2,PSMA6,PSMD1,RPS27A,PSMD8,PSMD3,TULP3,ADCY9,PSMC1,NUMB,ADCY7 |
| 3.705e-02 | -3.30 | APPIERTO_RESPONSE_TO_FENRETINIDE_DN | MSigDB lists | APPIERTO_RESPONSE_TO_FENRETINIDE_DN | 46 | 12 | 17377 | 2626 |
H2AFZ,NDUFA2,SIGMAR1,MDH2,UQCR10,BANF1,IARS2,MON1B,LDHA,MDH1,TRIM28,MTX2 |
| 3.705e-02 | -3.30 | MELLMAN_TUT1_TARGETS_DN | MSigDB lists | MELLMAN_TUT1_TARGETS_DN | 46 | 12 | 17377 | 2626 |
CAT,GSTK1,NDUFS1,KLF10,NQO1,RBM25,ITGB1,TALDO1,PARN,HAGH,PRDX1,DDX17 |
| 3.705e-02 | -3.30 | GO_NEURON_DEATH | MSigDB lists | GO_NEURON_DEATH | 46 | 12 | 17377 | 2626 |
CDK5,RB1,MAX,PIGT,SIAH1,HDAC7,BCL2,BCL2L1,PSEN1,APP,FADD,FAS |
| 3.705e-02 | -3.30 | IRITANI_MAD1_TARGETS_DN | MSigDB lists | IRITANI_MAD1_TARGETS_DN | 46 | 12 | 17377 | 2626 |
SRM,RPL29,DUT,BABAM1,RAD23B,SLC16A1,AHCY,DTD1,GGA2,FBL,PPA1,RPSA |
| 3.705e-02 | -3.30 | BIOCARTA_KERATINOCYTE_PATHWAY | MSigDB lists | BIOCARTA_KERATINOCYTE_PATHWAY | 46 | 12 | 17377 | 2626 |
PPP2CA,ETS2,RAF1,BCL2,MAP3K14,MAP3K5,MAPK14,MAPK1,ETS1,HRAS,MAPK3,FAS |
| 3.705e-02 | -3.30 | GO_REGULATION_OF_SKELETAL_MUSCLE_TISSUE_DEVELOPMENT | MSigDB lists | GO_REGULATION_OF_SKELETAL_MUSCLE_TISSUE_DEVELOPMENT | 46 | 12 | 17377 | 2626 |
TGFB1,TSC22D3,ARNTL,NACA,PRKAA1,FLOT1,NLN,BCL2,DDX5,ADRB2,FBXO22,DDX17 |
| 3.705e-02 | -3.30 | GO_CLATHRIN_COAT | MSigDB lists | GO_CLATHRIN_COAT | 46 | 12 | 17377 | 2626 |
GGA1,AP3M2,AP1M1,AP1S1,AP2B1,AP1B1,GGA2,CLTB,SYNRG,AP2S1,PICALM,NECAP2 |
| 3.706e-02 | -3.30 | Synaptic vesicle cycle | KEGG pathways | ko04721 | 63 | 16 | 7161 | 1149 |
ATP6V0A1,ATP6V1B2,ATP6V0B,ATP6V1D,NSF,DNM2,AP2B1,ATP6V0A2,ATP6V0C,CLTB,ATP6V1C1,ATP6V0D1,ATP6V0E1,UNC13C,AP2S1,ATP6V1G1 |
| 3.706e-02 | -3.30 | Synaptic vesicle cycle | KEGG pathways | hsa04721 | 63 | 16 | 7161 | 1149 |
ATP6V0A1,ATP6V1B2,ATP6V0B,ATP6V1D,NSF,DNM2,AP2B1,ATP6V0A2,ATP6V0C,CLTB,ATP6V1C1,ATP6V0D1,ATP6V0E1,UNC13C,AP2S1,ATP6V1G1 |
| 3.708e-02 | -3.29 | GO_POSITIVE_REGULATION_OF_DNA_BINDING | MSigDB lists | GO_POSITIVE_REGULATION_OF_DNA_BINDING | 41 | 11 | 17377 | 2626 |
CALM2,TGFB1,IRF4,TXN,KAT2A,HIPK2,CEBPG,HMGB2,SIRT2,EDF1,PARK7 |
| 3.708e-02 | -3.29 | LI_LUNG_CANCER | MSigDB lists | LI_LUNG_CANCER | 41 | 11 | 17377 | 2626 |
EIF5A,MDM2,RHOA,CDC42,RAC1,MAP4,YWHAZ,CDC25B,KIF11,PRDX1,TUBB |
| 3.708e-02 | -3.29 | GO_SUBSTANTIA_NIGRA_DEVELOPMENT | MSigDB lists | GO_SUBSTANTIA_NIGRA_DEVELOPMENT | 41 | 11 | 17377 | 2626 |
CALM2,RHOA,CDC42,CCDC14,DYNLL1,LDHA,ACTB,GLUD1,SIRT2,SEC16A,YWHAH |
| 3.708e-02 | -3.29 | GO_IMMUNOGLOBULIN_PRODUCTION | MSigDB lists | GO_IMMUNOGLOBULIN_PRODUCTION | 41 | 11 | 17377 | 2626 |
ERCC1,EXOSC6,GALNT2,CTNNBL1,PRKDC,TCF3,PMS2,MSH2,MSH6,FAS,POLQ |
| 3.708e-02 | -3.29 | GO_REGULATION_OF_TELOMERASE_ACTIVITY | MSigDB lists | GO_REGULATION_OF_TELOMERASE_ACTIVITY | 41 | 11 | 17377 | 2626 |
MAP3K4,CCT2,NVL,NEK7,PML,AURKB,MEN1,MAPK1,TERF1,POT1,MAPK3 |
| 3.708e-02 | -3.29 | RIZ_ERYTHROID_DIFFERENTIATION_HBZ | MSigDB lists | RIZ_ERYTHROID_DIFFERENTIATION_HBZ | 41 | 11 | 17377 | 2626 |
POU3F2,RB1,MCM5,TSC22D3,ZNF436,AFF1,SOX4,EYA2,CBX3,RLIM,PAPOLA |
| 3.708e-02 | -3.29 | FOXM1 transcription factor network | Pathway Interaction DB | foxm1pathway | 37 | 12 | 2226 | 426 |
PLK1,RB1,NFATC3,BIRC5,FOXM1,CENPF,CDC25B,AURKB,CHEK2,CCNB1,CDK2,CCNB2 |
| 3.713e-02 | -3.29 | Syndecan-2-mediated signaling events | Pathway Interaction DB | syndecan_2_pathway | 33 | 11 | 2226 | 426 |
TGFB1,RHOA,NF1,SDC2,ITGB1,EZR,PRKACA,MAPK1,HRAS,MAPK3,EPB41 |
| 3.713e-02 | -3.29 | N-cadherin signaling events | Pathway Interaction DB | ncadherinpathway | 33 | 11 | 2226 | 426 |
KIF5B,CALM2,RHOA,MAPRE1,AXIN1,RAC1,LRP5,ROCK1,CAMK2G,DCTN1,PIP5K1C |
| 3.713e-02 | -3.29 | E-cadherin signaling in the nascent adherens junction | Pathway Interaction DB | ecadherin_nascentaj_pathway | 33 | 11 | 2226 | 426 |
WASF2,RHOA,KLHL20,CDC42,RAC1,VAV2,AP1M1,NCKAP1,CYFIP2,ABI1,PIP5K1C |
| 3.713e-02 | -3.29 | EPO signaling pathway | Pathway Interaction DB | epopathway | 33 | 11 | 2226 | 426 |
CRKL,RAP1A,SHC1,VAV2,PTPN11,STAT1,BCL2,BCL2L1,MAPK14,LYN,HRAS |
| 3.713e-02 | -3.29 | SAM-dependent_MTases | interpro domains | IPR029063 | 122 | 26 | 18492 | 2768 |
METTL1,SRM,HEMK1,DNMT3A,NOP2,NSUN2,METTL5,METTL2A,PRMT2,GSTCD,METTL22,METTL3,DOT1L,METTL14,CMTR2,CAMKMT,FTSJ1,PRMT7,FBL,METTL26,METTL9,NSUN4,FTSJ3,DNMT1,CARM1,MRM2 |
| 3.720e-02 | -3.29 | Clathrin-mediated endocytosis | REACTOME pathways | R-HSA-8856828 | 137 | 31 | 10287 | 1696 |
COPS8,REPS2,TRIP10,ACTR3,EPN1,TGOLN2,AGFG1,ADRB2,UBQLN2,ARPC1A,RAB5B,STAM,REPS1,PICALM,TFRC,PIP5K1C,NECAP2,SCARB2,HGS,GRK2,RPS27A,SNX18,ARPC5,DNM2,AP2B1,COPS7B,COPS6,CLTB,ARRB2,AP2S1,DVL2 |
| 3.723e-02 | -3.29 | AGCTCCT,MIR-28 | MSigDB lists | AGCTCCT,MIR-28 | 88 | 20 | 17377 | 2626 |
TXNL1,MAX,NRAS,LUZP1,ZNF512,ATXN1,ARID1A,MEF2D,SRSF5,DDX39A,MAT2A,LRRC14,PTPRF,CLK3,CSNK1G1,NDE1,NAA60,SEH1L,HTRA2,SSRP1 |
| 3.723e-02 | -3.29 | GO_PROTEIN_KINASE_COMPLEX | MSigDB lists | GO_PROTEIN_KINASE_COMPLEX | 88 | 20 | 17377 | 2626 |
CCNC,BCCIP,PRKAB1,RB1CC1,PRKAA1,PRKAR1B,CDK13,CCNL2,PRKACA,ERC1,CCNK,RB1,PRDX3,CAB39,ATG13,MAP3K5,CDK2,GTF2H2,CDK12,PHKG2 |
| 3.723e-02 | -3.29 | Glucose metabolism | REACTOME pathways | R-HSA-70326 | 81 | 20 | 10287 | 1696 |
UGP2,GNPDA1,MDH2,PFKFB3,SLC25A12,ADPGK,GYG1,PKM,PRKACA,EPM2A,PPP2CA,CALM2,RPS27A,GOT2,MDH1,GPI,PGAM1,PHKG2,PFKP,SLC25A1 |
| 3.733e-02 | -3.29 | GSE2706_R848_VS_R848_AND_LPS_8H_STIM_DC_DN | MSigDB lists | GSE2706_R848_VS_R848_AND_LPS_8H_STIM_DC_DN | 166 | 34 | 17377 | 2626 |
UGP2,SEC61G,BIRC2,SLC25A37,CFLAR,SSR1,ANKRD28,CAPN2,HOMER1,RRN3,CLUAP1,BRPF3,SAR1A,JOSD1,RNF19A,OSTC,TMED2,BIRC3,TNFAIP3,MAP4K4,LYRM1,RAB3IP,CADM1,ARL5B,PLEKHF2,ARF4,UAP1,MAGT1,TAB2,SIAH2,RPS6KC1,NUDT11,CDKN2A,ESYT2 |
| 3.733e-02 | -3.29 | GO_ANTIGEN_RECEPTOR_MEDIATED_SIGNALING_PATHWAY | MSigDB lists | GO_ANTIGEN_RECEPTOR_MEDIATED_SIGNALING_PATHWAY | 166 | 34 | 17377 | 2626 |
LIME1,CUL1,BTN3A1,PSEN1,PSMD9,LYN,PSMD2,PSMD1,PSMA6,PTEN,PIK3R2,BCL2,PDPK1,NCK1,PSMA8,DENND1B,PSMB7,PSMA1,NFATC2,UBE2V1,PSMB9,PSMB3,STOML2,PSMC4,WAS,TAB2,RPS27A,CSK,PSMD3,PSMD8,STK11,MAPK1,PSMC1,HRAS |
| 3.733e-02 | -3.29 | GSE9960_HEALTHY_VS_GRAM_POS_SEPSIS_PBMC_UP | MSigDB lists | GSE9960_HEALTHY_VS_GRAM_POS_SEPSIS_PBMC_UP | 166 | 34 | 17377 | 2626 |
RAB14,GUK1,CKLF,NDUFB6,TSC22D3,CIB1,RPL15,CHCHD2,KIAA1586,NKRF,MAP7D1,NENF,SLC35B2,MAPK14,H2AFV,CCDC28A,EBP,C14orf119,RXRB,PWWP2B,UBE2Q2,HINT1,AGPAT2,SNAP29,IMPAD1,COX7A2L,SLC16A1,SSNA1,CISD2,TRIM52,OSTC,RTN3,DRAM2,EEF1D |
| 3.733e-02 | -3.29 | GO_MEIOTIC_CELL_CYCLE | MSigDB lists | GO_MEIOTIC_CELL_CYCLE | 166 | 34 | 17377 | 2626 |
UBR2,ACTR3,PTTG1,MYH9,TOP2B,SIRT2,TUBGCP2,FBXO5,SMC3,XRCC2,MSH2,CDC25B,MSH6,SMC4,PLK1,MND1,ASPM,NSUN2,TOP3A,TUBGCP5,MKI67,SMC2,RAD54B,MASTL,PPP2CA,RAD51C,KIF18A,GOLGA2,H2AFX,XRCC3,CDK2,TERF1,ESPL1,RAD51D |
| 3.733e-02 | -3.29 | LGALS8 (galectin 8) | protein interactions | 3964 | 113 | 26 | 17029 | 2761 |
SLC12A7,ENPP4,CLCN3,ACP2,ATG9A,EMB,ATP6V0A1,CUL1,RRAGC,LRRC8A,SLC4A2,SLC17A5,SLC12A9,GLMP,SPPL2A,SCARB2,SLC31A1,ADCY9,ATP13A3,ITGB1,ATP6V0A2,SLC26A2,SLC22A23,SLC12A2,ABCC1,PTPRK |
| 3.739e-02 | -3.29 | HAD-like_sf | interpro domains | IPR036412 | 78 | 18 | 18492 | 2768 |
CMAS,CTDP1,ATP13A1,ATP2C1,EPHX2,UBLCP1,PDXP,ATP1A1,ATP2A2,NT5DC1,NT5C3B,ATP13A3,LPIN2,NANP,CTDSP2,HDHD2,EYA2,TIMM50 |
| 3.748e-02 | -3.28 | proton-exporting ATPase activity, phosphorylative mechanism | molecular function | GO:0008553 | 13 | 5 | 17224 | 2647 |
ATP6V1C1,ATP2A2,ATP6V0D1,ATP2C1,ATP6V1G1 |
| 3.748e-02 | -3.28 | 3'-5' DNA helicase activity | molecular function | GO:0043138 | 13 | 5 | 17224 | 2647 |
GINS1,RECQL,BLM,GINS4,DHX9 |
| 3.748e-02 | -3.28 | tau-protein kinase activity | molecular function | GO:0050321 | 13 | 5 | 17224 | 2647 |
CDK5,MARK2,PHKG2,CSNK1D,PRKAA1 |
| 3.748e-02 | -3.28 | ubiquitin-ubiquitin ligase activity | molecular function | GO:0034450 | 13 | 5 | 17224 | 2647 |
UBE4B,UBE4A,RBX1,PPIL2,PRPF19 |
| 3.750e-02 | -3.28 | activation of MAPKK activity | biological process | GO:0000186 | 56 | 14 | 17256 | 2622 |
MAP3K4,CRKL,RAP1A,MAP3K7CL,RAF1,GADD45B,TAOK1,LAMTOR3,ADAM9,MAP3K14,MAP3K5,GNAI2,F2R,PSEN1 |
| 3.750e-02 | -3.28 | negative regulation of protein dephosphorylation | biological process | GO:0035308 | 56 | 14 | 17256 | 2622 |
FKBP1A,PPP1R9B,PPP1R37,PPP1R2,PPP1R8,PPME1,ENSA,PPP1R11,CRY2,CABIN1,ROCK1,PPP1R16B,GNAI2,MASTL |
| 3.750e-02 | -3.28 | AAGGGAT,MIR-188 | MSigDB lists | AAGGGAT,MIR-188 | 72 | 17 | 17377 | 2626 |
RAB14,TRIP12,LUZP1,TMEM39A,ZFP91,ILF3,ATXN1,SOX4,SNN,UBE2I,DLG5,CRKL,PTEN,BUD31,CDC25B,H3F3A,SLC12A2 |
| 3.750e-02 | -3.28 | MODULE_331 | MSigDB lists | MODULE_331 | 72 | 17 | 17377 | 2626 |
GOLPH3L,THOC1,C1orf35,ABCB10,PLEKHF2,CSDE1,HOMER1,RAD51C,ZNF777,PFDN4,UCHL5,PPA2,ARRB2,PPA1,ZNF770,ZNF146,ADNP2 |
| 3.750e-02 | -3.28 | KTGGYRSGAA_UNKNOWN | MSigDB lists | KTGGYRSGAA_UNKNOWN | 72 | 17 | 17377 | 2626 |
DLGAP4,RMI2,ORC1,CADM1,ZADH2,MIS12,SRSF1,EPB41,PRIM1,SEC61A1,SYNCRIP,SH3BP1,TIMM23,USP32,RBBP4,BTBD10,LUC7L2 |
| 3.750e-02 | -3.28 | REACTOME_TRIF_MEDIATED_TLR3_SIGNALING | MSigDB lists | REACTOME_TRIF_MEDIATED_TLR3_SIGNALING | 72 | 17 | 17377 | 2626 |
MAPKAPK3,RPS6KA1,MEF2A,IRF3,ELK1,MAPK14,MAP2K2,APP,MAPK3,PPP2CA,RPS27A,DUSP3,TAB2,TICAM1,CREB1,MAPK1,ATF2 |
| 3.750e-02 | -3.28 | REACTOME_RIG_I_MDA5_MEDIATED_INDUCTION_OF_IFN_ALPHA_BETA_PATHWAYS | MSigDB lists | REACTOME_RIG_I_MDA5_MEDIATED_INDUCTION_OF_IFN_ALPHA_BETA_PATHWAYS | 72 | 17 | 17377 | 2626 |
OTUD5,DDX58,UBE2D3,CYLD,TNFAIP3,SIKE1,IRF3,APP,ISG15,FADD,RPS27A,PIN1,TANK,NLRC5,MAVS,RNF135,PCBP2 |
| 3.761e-02 | -3.28 | GO_CELLULAR_RESPONSE_TO_ORGANIC_SUBSTANCE | MSigDB lists | GO_CELLULAR_RESPONSE_TO_ORGANIC_SUBSTANCE | 1779 | 295 | 17377 | 2626 |
RAB14,MAX,H2AFZ,ADD1,CXXC1,CCNB1,PARK7,EEF2K,USF1,PSMD1,DNM2,TIPARP,DNMT1,CDC5L,BAK1,KLF10,AKT2,GNG7,HNRNPF,MCM2,SMAD2,RPS27A,PSMD8,AXIN1,ITGB1,OGT,ATP6V0C,RNASEL,SMAD1,ARRB2,HDAC2,SLC25A33,POLR2K,SEC61G,HLA-E,PRKAA1,PSMD9,ITGB5,METTL3,CDC73,LMNA,TFAP4,FKBP1A,RNF121,PDXP,MEGF8,DAPK1,ATP6V0A2,SOCS5,ETV3,ARID1A,SRSF5,ELK1,KDM3A,PSMB3,AKAP1,FAS,DERL1,SEC31A,CAT,EPRS,FNTA,POLR2J,CSK,RBMX,PIAS2,SMPD4,CDK2,RNF14,ZC3HAV1,ATXN3,DNMT3A,RAB11B,UBR2,RAF1,WDTC1,BCL2L1,PRKACA,CPNE3,APP,GNB2,CCNA2,SHC1,SP100,RALB,MTMR4,ADCY9,SOCS6,CDKN1B,MAVS,DCTN1,ADCY7,ATP6V1G1,SHOC2,SEC61B,POLR2L,WBP2,POLR2D,ATP6V0A1,DNAJA1,SHCBP1,PSMB9,SERP1,SOCS7,ANKZF1,SEC61A1,JAK1,DGCR8,SAFB,HIPK2,STAT1,ATF6,TICAM1,LRP8,CSNK1D,POU3F2,FLOT1,SDF2L1,AKT1S1,IP6K2,BLM,IL21R,FOXO3,HLA-A,GTF2F1,CAPN2,PSMD2,PRDM4,FUT8,PTPN11,AXIN2,ANXA5,MAP3K14,CREB1,UBE2M,NCOA2,HNRNPM,PDPK1,PPP3CA,TNFAIP3,KAT2A,DENND4C,KCNQ1,KLF6,PDE3B,POLR2A,CBX3,YIF1A,KEAP1,TATDN2,WNT5B,PML,HMGB2,ASNA1,PSAP,CD81,YWHAH,CPEB2,FAM83G,BYSL,RORB,SLC29A1,SIRT2,MAPK14,BECN1,BIRC2,SSR1,ABL2,RAB8A,RAP1A,EIF4A3,IL6ST,RAB35,PIK3R2,AKR1B1,ZFYVE27,CARM1,PTPRK,TRIM8,EZR,CDC6,IL12RB1,BRCA1,SOX4,PRKRA,DPYSL3,PAF1,SOCS4,ADAM9,ZNF268,CLU,CHEK2,PSMC1,ATP6V0E1,UBE2D3,AGTRAP,LAMTOR3,CIB1,TIA1,THRAP3,SRRT,RHBDD1,RB1,CTR9,BCL2,ATP6V0D1,PREB,ABHD2,POLR2I,AACS,GBA,PSMA1,KRAS,SYVN1,APPL1,DAPK3,ISG15,IRF5,RXRB,PSMC4,GNAS,SYNCRIP,NFIL3,SLC16A1,NUP62,RUVBL2,EHD4,ADNP2,SMARCD1,RRAGC,IRF3,ATP6V1B2,TWF2,LYN,DUSP22,HNRNPA2B1,PDK2,ATP6V0B,PSMA6,MDM2,CORO1A,AHCYL1,PDIA6,CTDSP2,HTRA2,BIRC3,POLR2G,PSMA8,SELPLG,PSMB7,SLC26A6,EDEM2,ATP1A1,IDE,PSMD3,STAT6,NCOA1,SCARB1,SMURF1,MAPK1,ABCA1,SMAD4,PARD3,RAE1,PAWR,AP3S1,DNAJB9,PTPN2,FGFR3,IRF4,CTSS,ARHGEF2,STAT3,CAMK2G,MYO5A,RNF5,PAQR6,TGFB1,PPP1R9B,ADAM17,RHOA,PRKDC,PRKAR1B,RANGAP1,MEN1,MAPK3,HLA-B,UPF1,TRIM26,ATP6V1D,TWSG1,E2F1,NR2F2,ATP6V1C1,PLOD3 |
| 3.763e-02 | -3.28 | GSE8921_UNSTIM_VS_TLR1_2_STIM_MONOCYTE_24H_DN | MSigDB lists | GSE8921_UNSTIM_VS_TLR1_2_STIM_MONOCYTE_24H_DN | 189 | 38 | 17377 | 2626 |
LZTR1,PNISR,MCM10,DCTN2,AGPAT1,SIRT2,TMEM165,USP5,PPIG,PPME1,SOCS6,DAPK1,COPS7B,CPSF4,KCNAB2,CFL1,CAMK2G,HNRNPM,RBM15B,ELOVL5,MAPKAPK3,PPP1R21,MRS2,LDHA,AMDHD2,TOLLIP,MTR,SERP1,GPR137,ATP1A1,TATDN2,CORO1C,PPP3R1,ADAM9,VPS4A,KLHDC4,PGAM1,AP2S1 |
| 3.763e-02 | -3.28 | GSE24634_IL4_VS_CTRL_TREATED_NAIVE_CD4_TCELL_DAY3_UP | MSigDB lists | GSE24634_IL4_VS_CTRL_TREATED_NAIVE_CD4_TCELL_DAY3_UP | 189 | 38 | 17377 | 2626 |
HIVEP3,IMMT,KIAA0100,PDAP1,TOR3A,MCCC1,SDC2,MAN2B1,STMN1,BCAP31,CCDC28A,LMNA,CREM,GNS,ANKRD26,GOLM1,IRF4,SNRNP25,APLP2,ADCY9,MEA1,AHCY,RNF5,MLEC,NUSAP1,HAGH,PI4K2A,CAT,TRAM2,AHNAK,NSF,WNT5B,NFIL3,PDXK,ZMIZ1,SMAD1,EHD4,PITRM1 |
| 3.763e-02 | -3.28 | GSE19888_ADENOSINE_A3R_ACT_VS_TCELL_MEMBRANES_ACT_AND_A3R_INH_PRETREAT_IN_MAST_CELL_DN | MSigDB lists | GSE19888_ADENOSINE_A3R_ACT_VS_TCELL_MEMBRANES_ACT_AND_A3R_INH_PRETREAT_IN_MAST_CELL_DN | 189 | 38 | 17377 | 2626 |
MIF,IVNS1ABP,HMGXB3,STRN4,ARGLU1,ARID1B,SRRT,SNAPC4,HMG20A,FZD6,FGFR3,HUWE1,RPAP1,ANP32A,TTC3,CYC1,TP53BP2,LDLRAD3,CNNM3,PABPC1,ABCC1,SPTAN1,CELSR2,TMEM216,UBE2V1,MEF2D,TANC1,TAZ,LUC7L,RPS9,PTPRF,MAP3K4,GOLGA4,UPF1,ETS2,DUSP11,MBD6,REEP4 |
| 3.763e-02 | -3.28 | GSE11057_NAIVE_CD4_VS_PBMC_CD4_TCELL_DN | MSigDB lists | GSE11057_NAIVE_CD4_VS_PBMC_CD4_TCELL_DN | 189 | 38 | 17377 | 2626 |
FEZ2,COPA,REPS2,SESTD1,B4GALT5,RHOC,TRAK1,TKT,NOTCH2,SND1,RGS2,DUSP22,SRXN1,TMCC3,RAB8A,ATP6V0B,CCDC50,ATP2A2,RALB,ZNF710,GNAI2,SAP30,POU2AF1,GALC,LAP3,EMP3,CAT,MTHFD2,WDR11,PDLIM1,SNAP23,NFIL3,OAZ2,ZDHHC7,ACTB,CTSA,GALNT10,LTA4H |
| 3.763e-02 | -3.28 | GSE360_CTRL_VS_B_MALAYI_LOW_DOSE_DC_UP | MSigDB lists | GSE360_CTRL_VS_B_MALAYI_LOW_DOSE_DC_UP | 189 | 38 | 17377 | 2626 |
RAB14,RHOC,DLGAP4,SLC29A1,TMED3,BLM,ITGB5,FAM8A1,MYEF2,KTN1,FANCL,ZNF75D,CDC42,ETV6,CDKN1B,CYB5R1,TMED2,TRIM14,MKLN1,RPS24,RRM2,MCL1,EIF3A,DDX17,CAND1,SH3BP5,PPP2CA,PON2,SERTAD2,RPS27A,BIRC5,MFAP1,CCDC69,WIPI2,RBPJ,IDH3B,PGAM1,TAF6 |
| 3.763e-02 | -3.28 | GSE18281_SUBCAPSULAR_CORTICAL_REGION_VS_WHOLE_MEDULLA_THYMUS_UP | MSigDB lists | GSE18281_SUBCAPSULAR_CORTICAL_REGION_VS_WHOLE_MEDULLA_THYMUS_UP | 189 | 38 | 17377 | 2626 |
POLA2,PRKAB1,ADD1,TSC2,SDC2,MOGS,AGPAT1,PSEN1,ZNF79,FANCI,APLP2,HDAC7,SSBP3,ATG13,CDC25B,GEMIN4,TPCN1,GM2A,DCTN1,BRD4,PRRC2A,ZNF500,PBK,ANAPC2,ESYT1,EDEM2,ELK1,MEN1,LUC7L,ERC1,POLR2A,DSN1,NEIL3,CEP55,ATP6V0C,TCOF1,NCOA1,BRD9 |
| 3.763e-02 | -3.28 | GSE360_L_MAJOR_VS_B_MALAYI_HIGH_DOSE_DC_UP | MSigDB lists | GSE360_L_MAJOR_VS_B_MALAYI_HIGH_DOSE_DC_UP | 189 | 38 | 17377 | 2626 |
CYTIP,PLXNC1,B4GALT5,SF3B1,PDAP1,GADD45G,HMGN3,CHD1,FZD6,RGS1,CNOT3,CFLAR,OIP5,PRKD3,TNFAIP8,ZKSCAN1,PPIL2,FAM89B,HNRNPM,VPS13B,RHOBTB3,TNFAIP3,LDHA,KRAS,ARHGEF12,ANKRD46,GLOD4,OPTN,KIF2A,GOLGA4,PCM1,MTHFD2,ETS2,JAK1,PSMD8,ZNF268,ATMIN,PRPF4B |
| 3.763e-02 | -3.28 | GSE26912_TUMORICIDAL_VS_CTRL_MACROPHAGE_UP | MSigDB lists | GSE26912_TUMORICIDAL_VS_CTRL_MACROPHAGE_UP | 189 | 38 | 17377 | 2626 |
CCDC93,KARS,NDUFA5,GCLM,FEZ2,CDS2,AGTRAP,EYA1,PAWR,NCKAP1,SEC16A,FOXO3,XPR1,SLC25A36,NUDT19,SLC1A4,ATP2A2,HDAC7,PDS5B,DCTN1,LDHB,RBX1,NCK1,TOLLIP,KDM3A,NDRG3,SLTM,ANKRD46,RHOB,PTPRF,TRIM47,LTBP4,TWSG1,VPS26B,PSMD3,TULP3,PKD2,PTOV1 |
| 3.764e-02 | -3.28 | atypical | COSMIC cancer mutations | atypical | 518 | 92 | 17385 | 2587 |
TP53RK,RPS6KA1,RAF1,SF3B1,CSNK2A1,SMARCA4,PRKACA,LYN,MAPK14,TWF2,EEF2K,CDK5,ABL2,CDKN2C,PRKD3,PDK2,ATP2A2,NEK6,SCYL3,CDK12,SRPK2,PLK1,PLK3,ERMP1,NRAS,BRD4,AKT2,PBK,TLK1,MAP4K4,SLBP,PKMYT1,AURKB,STK17B,TRIM28,MAP3K4,JAK1,HNRNPR,CLK3,FASTK,LIMK1,STK38,HIPK2,STK11,CHEK2,RNASEL,MAPK1,SMAD4,PPP2R2D,PRPF4B,EWSR1,TRIO,PRKAA1,SCYL1,CDK13,ADCK5,EIF2AK4,CSNK1A1,SCYL2,RB1,FGFR3,HUWE1,PTEN,EFTUD2,DAPK1,PHKG2,CAMK2G,CSNK1G3,PDPK1,CSNK1G2,TNFAIP3,NEK7,MAP4K3,EIF2AK1,KRAS,ARID1A,MEN1,MARK2,MAP2K2,DAPK3,MAPK3,MASTL,PRDX3,MAPK6,MAP3K5,BRWD3,RPS6KC1,CDK2,NRBP1,HRAS,HIPK3,CDKN2A |
| 3.765e-02 | -3.28 | transcription regulatory region DNA binding | molecular function | GO:0044212 | 877 | 154 | 17224 | 2647 |
RORB,IER2,MAX,H2AFZ,CXXC1,SNAPC4,MYEF2,PARK7,GLMP,CREM,USF1,GLIS2,ZNF639,ETV6,ZNF200,CRY2,SMARCE1,TIPARP,MYBL1,ARID4A,CCAR1,CARM1,CDC5L,SP3,DEAF1,KLF10,BAZ2A,GABPA,EAF2,BRCA1,SOX4,UBTF,HHEX,SMAD2,E2F4,PRDX5,ACTB,TFDP2,SMAD1,E2F2,HDAC2,ZNF564,HIVEP3,DHX9,CTCF,MEF2A,CDK13,THRAP3,TTF1,TFAP4,RB1,MLX,NFATC3,MED8,KLF16,MBD2,SSBP3,ZNF746,ZNF335,YBX1,TNRC18,ETV3,FOXK1,ZMYND11,MTA2,LDB1,MYBL2,ELK1,KDM3A,IRF5,ZNF174,RXRB,XRCC5,ETS2,RBMX,NFIL3,NLRC5,TBPL1,CEBPG,RUVBL2,YY1,RBBP4,TCF12,TRERF1,IVNS1ABP,FOXM1,SUZ12,SMARCA4,IRF3,RCOR3,MXD1,RRN3,NRF1,MTA1,GMEB1,ATF2,CDK12,CGGBP1,POU2AF1,KDM3B,KAT7,E2F3,WBP2,PCGF6,NFATC2,MEF2D,MBD3,TAF2,VEZF1,RBL1,SAFB,MAFK,STAT6,ARNTL,STAT1,ATF6,H3F3A,AKNA,SMAD4,CBX4,ATMIN,POU3F2,TCF3,AGO2,ARID5A,KLF13,NKRF,ETS1,FOXO3,IRF4,SUV39H2,PRDM4,BRD7,H2AFY,CARF,CREB1,STAT3,NCOA2,ZFP64,PSPC1,ZNF202,RCOR1,MEN1,KLF6,TFEB,TFE3,PITX1,TFDP1,E2F1,HMGB2,RBPJ,USF2,PURA,IFI16 |
| 3.767e-02 | -3.28 | integral component of mitochondrial membrane | cellular component | GO:0032592 | 68 | 16 | 18223 | 2701 |
BAK1,COA3,TOMM20,IMMT,ABCB10,RHOT1,SLC25A44,TOMM40,RHOT2,CHCHD6,MPC1,CHCHD3,TIMM23,TIMM17A,SLC25A19,APOOL |
| 3.773e-02 | -3.28 | ZHANG_RESPONSE_TO_IKK_INHIBITOR_AND_TNF_DN | MSigDB lists | ZHANG_RESPONSE_TO_IKK_INHIBITOR_AND_TNF_DN | 99 | 22 | 17377 | 2626 |
MCM10,ERF,WDHD1,ZNRF3,ARID1A,ORC1,SEPT7,GGA2,GIT2,RHOB,TMEM201,DTL,C1GALT1,SMC3,RBL1,ZNF367,DAPK1,MAP3K5,NR2F2,ATF2,E2F2,MSH6 |
| 3.778e-02 | -3.28 | GSE32901_TH1_VS_TH17_NEG_CD4_TCELL_UP | MSigDB lists | GSE32901_TH1_VS_TH17_NEG_CD4_TCELL_UP | 110 | 24 | 17377 | 2626 |
TCF12,SHOC2,TMEM39A,SRGN,TAP1,RNPS1,TIA1,EIF2A,KCMF1,SFXN5,SLC25A36,MOSPD3,PA2G4,RBL1,JAZF1,DTX4,RNF38,PIEZO1,EIF5,NUDT11,GLCCI1,STAT3,LRRC59,ATF2 |
| 3.784e-02 | -3.27 | protein localization to lysosome | biological process | GO:0061462 | 36 | 10 | 17256 | 2622 |
NAGPA,GCC2,SCARB2,LARS,HGS,RAB7A,LAMTOR4,VPS4A,CLU,CD81 |
| 3.784e-02 | -3.27 | negative regulation of DNA replication | biological process | GO:0008156 | 36 | 10 | 17256 | 2622 |
SMC3,GTPBP4,TIMELESS,CDC6,CHEK2,BLM,ZNF830,TERF1,TTF1,TERF2 |
| 3.784e-02 | -3.27 | positive regulation of TOR signaling | biological process | GO:0032008 | 36 | 10 | 17256 | 2622 |
TELO2,LARS,MIOS,LAMTOR4,WDR59,LAMTOR3,RRAGC,SEH1L,RHEB,MLST8 |
| 3.784e-02 | -3.27 | oxidoreduction coenzyme metabolic process | biological process | GO:0006733 | 126 | 27 | 17256 | 2622 |
GALK1,NADSYN1,COQ8A,COQ10B,MDH2,TKT,LDHA,NADK2,OGDH,ADPGK,PKM,PDHX,MPC1,COQ4,NAXE,DHTKD1,MDH1,GPI,TALDO1,PARP10,GPD1L,PGAM1,PDSS2,PFKP,KCNAB2,RNLS,LDHB |
| 3.786e-02 | -3.27 | human chr14q32.33 | chromosome location | human chr14q32.33 | 57 | 11 | 26185 | 2809 |
CEP170B,INF2,CDCA4,GPR132,SIVA1,MTA1,ZFYVE21,KLC1,XRCC3,APOPT1,PACS2 |
| 3.790e-02 | -3.27 | cytosolic small ribosomal subunit | cellular component | GO:0022627 | 47 | 12 | 18223 | 2701 |
RPS15,RPS2,RPS27A,RPS14,EIF2D,RPS10,RPS24,EIF2A,RPS26,RPS9,RPSA,MCTS1 |
| 3.792e-02 | -3.27 | V$HNF4_01 | MSigDB lists | V$HNF4_01 | 253 | 49 | 17377 | 2626 |
PTMS,PKP4,NDUFS1,PRKCSH,UQCR10,SRSF6,AGPAT1,UBE4A,AP1B1,RAPGEF6,PIP4K2A,RNF103,ARL6IP6,FAM192A,MED8,NEK6,SEC24C,SRSF4,PELO,ARL6IP1,TIMELESS,GLTP,CREB1,RPRD1B,RNF5,SLC25A1,NIPSNAP1,GCC2,MLEC,BAZ2A,NET1,AKT2,SLC26A6,WDR82,ADRB2,PLEC,SLC25A5,PDE3B,MARK2,BSDC1,RHOB,GOLGA4,ZNF777,DUSP3,VCPIP1,RBMS1,FKBP5,ZSWIM3,ACSF2 |
| 3.795e-02 | -3.27 | LisH | smart domains | SM00667 | 23 | 7 | 9493 | 1367 |
GID8,RMND5A,TCOF1,MKLN1,FOPNL,SSBP3,SMU1 |
| 3.799e-02 | -3.27 | luminal_NS_carcinoma | COSMIC cancer mutations | luminal_NS_carcinoma | 52 | 13 | 17385 | 2587 |
FGFR3,RB1,ABCA3,KEAP1,NRAS,PTEN,ACAP1,KRAS,BRCA1,GEN1,HRAS,CDKN2A,MSH6 |
| 3.799e-02 | -3.27 | breast-carcinoma-luminal_NS_carcinoma | COSMIC cancer mutations | breast-carcinoma-luminal_NS_carcinoma | 52 | 13 | 17385 | 2587 |
FGFR3,RB1,ABCA3,KEAP1,NRAS,PTEN,ACAP1,KRAS,BRCA1,GEN1,HRAS,CDKN2A,MSH6 |
| 3.799e-02 | -3.27 | ovary-carcinoma-adenocarcinoma | COSMIC cancer mutations | ovary-carcinoma-adenocarcinoma | 192 | 38 | 17385 | 2587 |
TRIP12,NF1,SF3B1,NUP54,MED13L,EIF2AK4,NOTCH2,WRNIP1,CDKN2C,NUP210,PTEN,AHSA1,MSH2,AQR,STAT3,HMGN5,FAM118B,POLK,VHL,MAP7D1,KRAS,ARID1A,ERC1,GNAS,AHNAK,TBC1D17,HSPBP1,RBM47,JAK1,SAFB,USP20,STK11,WDR91,MYO9A,SMAD4,HRAS,AAAS,CDKN2A |
| 3.801e-02 | -3.27 | TRRAP (transformation/transcription domain associated protein) | protein interactions | 8295 | 108 | 25 | 17029 | 2761 |
USP7,TELO2,MAX,H2AFZ,MPHOSPH8,KAT2A,NCK1,BTAF1,TCF3,CUL1,NFATC2,SUPT20H,TAF6L,USP22,SUPT7L,FOXO3,MEAF6,USF1,JAZF1,E2F4,MED15,E2F1,RUVBL2,TAF6,SGF29 |
| 3.802e-02 | -3.27 | acinar_adenocarcinoma | COSMIC cancer mutations | acinar_adenocarcinoma | 27 | 8 | 17385 | 2587 |
KIF5B,FGFR3,KRAS,STK11,NRAS,PTEN,EML4,SMAD4 |
| 3.809e-02 | -3.27 | BIOCARTA_IL2_PATHWAY | MSigDB lists | BIOCARTA_IL2_PATHWAY | 22 | 7 | 17377 | 2626 |
CSNK2A1,JAK1,SHC1,ELK1,HRAS,RAF1,MAPK3 |
| 3.809e-02 | -3.27 | BIOCARTA_PGC1A_PATHWAY | MSigDB lists | BIOCARTA_PGC1A_PATHWAY | 22 | 7 | 17377 | 2626 |
CALM2,MEF2A,PPP3CA,PPP3CB,MEF2D,YWHAH,CAMK2G |
| 3.809e-02 | -3.27 | GCM_FANCL | MSigDB lists | GCM_FANCL | 22 | 7 | 17377 | 2626 |
FANCL,SS18L1,LARS,CHTOP,ZNF512,LUC7L3,CRNKL1 |
| 3.809e-02 | -3.27 | REACTOME_PRE_NOTCH_TRANSCRIPTION_AND_TRANSLATION | MSigDB lists | REACTOME_PRE_NOTCH_TRANSCRIPTION_AND_TRANSLATION | 22 | 7 | 17377 | 2626 |
RBPJ,NOTCH2,MAML1,KAT2A,TFDP1,E2F1,E2F3 |
| 3.809e-02 | -3.27 | REACTOME_GRB2_EVENTS_IN_ERBB2_SIGNALING | MSigDB lists | REACTOME_GRB2_EVENTS_IN_ERBB2_SIGNALING | 22 | 7 | 17377 | 2626 |
KRAS,NRAS,MAPK1,MAP2K2,HRAS,RAF1,MAPK3 |
| 3.809e-02 | -3.27 | HASLINGER_B_CLL_WITH_11Q23_DELETION | MSigDB lists | HASLINGER_B_CLL_WITH_11Q23_DELETION | 22 | 7 | 17377 | 2626 |
PCSK7,UBE4A,LPCAT1,BIRC2,PICALM,PABPC4,FUT8 |
| 3.809e-02 | -3.27 | MODULE_233 | MSigDB lists | MODULE_233 | 22 | 7 | 17377 | 2626 |
UBE2D3,UBE2V1,GCLM,UBE3C,TRIP12,UBE2I,UBE2M |
| 3.809e-02 | -3.27 | MODULE_372 | MSigDB lists | MODULE_372 | 22 | 7 | 17377 | 2626 |
LARS,SLC26A2,ATAD2,TWSG1,KIF11,RCOR3,MSH2 |
| 3.809e-02 | -3.27 | GO_NEGATIVE_REGULATION_OF_ORGANELLE_ASSEMBLY | MSigDB lists | GO_NEGATIVE_REGULATION_OF_ORGANELLE_ASSEMBLY | 22 | 7 | 17377 | 2626 |
CHMP2A,CHMP4B,BRCA1,FEZ2,CHMP4A,PHF23,MAP4 |
| 3.809e-02 | -3.27 | GO_HYDROLASE_ACTIVITY_HYDROLYZING_N_GLYCOSYL_COMPOUNDS | MSigDB lists | GO_HYDROLASE_ACTIVITY_HYDROLYZING_N_GLYCOSYL_COMPOUNDS | 22 | 7 | 17377 | 2626 |
MAN2A2,PCNA,MPG,OGG1,NEIL3,NEIL2,MBD4 |
| 3.809e-02 | -3.27 | GO_NUCLEOTIDE_EXCISION_REPAIR_DNA_DUPLEX_UNWINDING | MSigDB lists | GO_NUCLEOTIDE_EXCISION_REPAIR_DNA_DUPLEX_UNWINDING | 22 | 7 | 17377 | 2626 |
RBX1,GTF2H2,RPS27A,CHD1L,DDB1,XPA,RAD23B |
| 3.809e-02 | -3.27 | STAMBOLSKY_RESPONSE_TO_VITAMIN_D3_DN | MSigDB lists | STAMBOLSKY_RESPONSE_TO_VITAMIN_D3_DN | 22 | 7 | 17377 | 2626 |
NRF1,CDS2,CKLF,HMGN4,MEAF6,DAPK1,NUP54 |
| 3.809e-02 | -3.27 | BIOCARTA_INSULIN_PATHWAY | MSigDB lists | BIOCARTA_INSULIN_PATHWAY | 22 | 7 | 17377 | 2626 |
CSNK2A1,SHC1,ELK1,HRAS,RAF1,MAPK3,PTPN11 |
| 3.810e-02 | -3.27 | CSA_PPIASE_1 | prosite domains | PS00170 | 19 | 6 | 12060 | 1670 |
PPIF,PPIB,CWC27,PPIG,PPIE,PPIL2 |
| 3.810e-02 | -3.27 | CHROMO_1 | prosite domains | PS00598 | 19 | 6 | 12060 | 1670 |
MPHOSPH8,SUV39H2,CHD3,CHD1,CBX4,CBX3 |
| 3.817e-02 | -3.27 | zinc ion binding | molecular function | GO:0008270 | 792 | 140 | 17224 | 2647 |
RORB,MIB2,ADA2,KDM4A,CXXC1,TRIM11,DNAJC24,USP39,LACTB2,SIRT2,RBM4,POLR3K,BIRC2,KCMF1,TRIM65,TCEA1,MARCH2,RNF26,ZNRD1,DNMT1,TRIM14,TRIM8,ZCCHC10,RBX1,EHMT1,USP22,BRCA1,ZFAND5,ZMYM3,TRIM4,CXXC4,TRIM47,TIMM13,CHD3,PTER,BAZ1B,TRIM52,ZSWIM3,TRAF5,ZMAT3,DDX58,ZCCHC9,ZCCHC8,POLR2K,CTCF,RLF,PIKFYVE,CPSF4,MORC3,TIMM8B,POLR2I,ZNF84,ZMYND11,NQO2,MTA2,DCTD,MTR,SF3A2,MATR3,RXRB,EPRS,SIAH2,PIAS2,YY1,ZNF830,RNF139,MBD1,ZNF207,TRIM41,CYLD,TRAF7,UBR2,ZADH2,USP5,PHC2,CYHR1,MDM2,ZNF75D,KDM2A,SIAH1,MTA1,ZCCHC2,AKAP8,SAP30L,TIMP2,POLR2L,PGGT1B,KAT7,GLO1,KDM1B,TRIM28,AMZ2,ZNF282,IDE,NSMCE2,PDXK,TRIM32,LTA4H,ZC3HC1,ZNF146,USP13,DBF4,BRAP,MYNN,LANCL1,BLM,ZNF92,NEIL2,TUT4,SUV39H2,SEC24C,PRDM4,LTN1,ARHGEF2,FBXL19,GTF2H2,S100A6,RNF5,TK1,TNFAIP3,CSRP1,ZMYM5,TOP3A,RABIF,ZNF407,ZFR,UPF1,TRIM26,POLE,L3MBTL3,NEIL3,ZNF330,DTX4,PML,KMT2B,USP20,ZMIZ1,NR2F2,VPS29,ZSWIM6 |
| 3.818e-02 | -3.27 | GSE3982_BCELL_VS_BASOPHIL_UP | MSigDB lists | GSE3982_BCELL_VS_BASOPHIL_UP | 172 | 35 | 17377 | 2626 |
CORO7,ST13,GGA1,TCF3,PXMP2,GGA2,RUFY1,SRRT,PABPC4,ZNF473,THADA,MTMR4,DBNDD1,TTC4,MAVS,GEMIN4,TTPAL,AMPD2,CSNK1G2,NASP,PPT1,ZNF202,ABCF2,TEX10,ILF3,DCLRE1C,PRIM1,FBXO21,C1orf109,FAM3C,MLYCD,KPNA2,DMWD,LTA4H,CHMP7 |
| 3.820e-02 | -3.26 | SMAD binding | molecular function | GO:0046332 | 71 | 17 | 17224 | 2647 |
TCF12,MEF2A,MEN1,FKBP1A,SMAD2,AXIN1,HIPK2,AXIN2,PML,DDX5,YY1,SMAD1,SMURF1,SMAD4,ZC3H3,PURA,TOB1 |
| 3.825e-02 | -3.26 | LANDIS_ERBB2_BREAST_TUMORS_324_UP | MSigDB lists | LANDIS_ERBB2_BREAST_TUMORS_324_UP | 138 | 29 | 17377 | 2626 |
WSB2,CMAS,IER2,PPP3CA,CSRP1,ELL2,DAP,ANKH,ANK3,EZR,RRM2,SLC29A1,TMED3,SOX4,CHMP2B,MIEN1,SERP1,EBP,RTKN,PTPN2,RAB18,STRBP,ORMDL2,DCK,FUT8,SLAIN1,LMAN1,SLC12A2,SPTAN1 |
| 3.828e-02 | -3.26 | VOC | prosite domains | PS51819 | 6 | 3 | 12060 | 1670 |
GLO1,HPDL,GLOD4 |
| 3.828e-02 | -3.26 | BRIX | prosite domains | PS50833 | 6 | 3 | 12060 | 1670 |
RPF2,PPAN,BRIX1 |
| 3.828e-02 | -3.26 | GAR | prosite domains | PS51460 | 6 | 3 | 12060 | 1670 |
DST,GAS2,MACF1 |
| 3.828e-02 | -3.26 | RAP | prosite domains | PS51286 | 6 | 3 | 12060 | 1670 |
FASTKD3,TBRG4,FASTK |
| 3.828e-02 | -3.26 | BIR_REPEAT_1 | prosite domains | PS01282 | 6 | 3 | 12060 | 1670 |
BIRC3,BIRC2,XIAP |
| 3.828e-02 | -3.26 | GSE360_DC_VS_MAC_B_MALAYI_HIGH_DOSE_DN | MSigDB lists | GSE360_DC_VS_MAC_B_MALAYI_HIGH_DOSE_DN | 195 | 39 | 17377 | 2626 |
MIF,CHMP2A,NUP188,TSC22D3,RHOC,SNX15,LAGE3,FKBP2,FOXO3,PDXDC1,PARK7,RGS1,RNF103,CALM2,DNAJC8,SNUPN,ATP2A2,RRBP1,TALDO1,KCNAB2,TGFB1,NSDHL,EMP3,CADM1,NEU1,ISG15,OPTN,MYO1F,KRIT1,CHD3,PPP3R1,ARAP1,SSNA1,CLN3,CHMP7,LTA4H,HRAS,IFI16,CDKN2A |
| 3.828e-02 | -3.26 | GSE17721_POLYIC_VS_PAM3CSK4_6H_BMDC_UP | MSigDB lists | GSE17721_POLYIC_VS_PAM3CSK4_6H_BMDC_UP | 195 | 39 | 17377 | 2626 |
POU3F2,KARS,DNMT3A,MCM10,SUMF1,PXMP2,SLC35B2,CUTC,CPNE3,ABHD16A,RBM17,PDCD10,RABGAP1L,ETV6,LPIN2,BCL2,CLDND1,SLC35C2,PACS2,PTPN18,RAD51AP1,RCOR1,POLR3GL,PFKFB3,OGFR,KRTCAP2,ATP6V1D,PDLIM1,PPP2R5A,UBXN2B,GADD45B,NFIL3,EXOC4,RGL1,MRPL13,TOB1,SMAD4,CBX4,CSNK1D |
| 3.828e-02 | -3.26 | GSE17186_BLOOD_VS_CORD_BLOOD_CD21LOW_TRANSITIONAL_BCELL_DN | MSigDB lists | GSE17186_BLOOD_VS_CORD_BLOOD_CD21LOW_TRANSITIONAL_BCELL_DN | 195 | 39 | 17377 | 2626 |
RAB14,CDCA8,ZFYVE21,TAF6L,PMF1,SLC35B2,SLC12A9,APP,MBD4,FBXO3,RPN1,ASAP2,RALB,LPIN2,TPST1,ZNF710,LPCAT1,TMBIM1,KDM3B,PHF10,TCTEX1D2,MKI67,E2F3,MIER2,USP22,GALNT7,ARMC8,FADD,GOLGA7,TXNDC16,BIRC5,HPS5,HIPK2,MYO18A,SEL1L,ARAP1,ADAM9,DYNC1LI2,TMEM131 |
| 3.837e-02 | -3.26 | Ubiquitin-dependent degradation of Cyclin D | REACTOME pathways | R-HSA-75815 | 52 | 14 | 10287 | 1696 |
PSMD2,PSMD1,PSMA6,PSMA8,RPS27A,PSMD8,PSMD3,PSMB7,PSMA1,PSMB9,PSMD9,PSMC1,PSMB3,PSMC4 |
| 3.837e-02 | -3.26 | Ubiquitin-dependent degradation of Cyclin D1 | REACTOME pathways | R-HSA-69229 | 52 | 14 | 10287 | 1696 |
PSMD2,PSMD1,PSMA6,PSMA8,RPS27A,PSMD8,PSMD3,PSMB7,PSMA1,PSMB9,PSMD9,PSMC1,PSMB3,PSMC4 |
| 3.837e-02 | -3.26 | MLLT6 (MLLT6, PHD finger containing) | protein interactions | 4302 | 48 | 13 | 17029 | 2761 |
TCF12,UNK,UBQLN4,GCC2,MED15,CEBPG,CUL3,NSD3,ZBTB22,ATF2,APP,EEF1D,DOT1L |
| 3.837e-02 | -3.26 | ABCC2 (ATP binding cassette subfamily C member 2) | protein interactions | 1244 | 48 | 13 | 17029 | 2761 |
RAB14,TOMM20,HSPA4,NDUFA2,RAB11B,MRPS26,CHCHD2,NDUFB9,NDUFS8,MCPH1,PICALM,MRPL57,SSR1 |
| 3.837e-02 | -3.26 | HCCS (holocytochrome c synthase) | protein interactions | 3052 | 48 | 13 | 17029 | 2761 |
RAB21,RAB14,MID1IP1,TIMMDC1,PHF23,NSDHL,GBA,NDUFA4,CYC1,FAM136A,ESYT1,TMX1,RDH11 |
| 3.837e-02 | -3.26 | SCARA3 (scavenger receptor class A member 3) | protein interactions | 51435 | 48 | 13 | 17029 | 2761 |
PBXIP1,FAM207A,XIAP,C19orf25,TNPO3,IKBIP,XPO7,SENP1,ABHD14A,CMTM6,HLA-A,DNAJB9,LMNA |
| 3.838e-02 | -3.26 | neoplasm | COSMIC cancer mutations | neoplasm | 15237 | 2295 | 17385 | 2587 |
HECA,ZBTB10,ABCC10,HEXB,CCNL2,FBXO22,EEF2K,THAP4,RAD23B,ATP13A3,DNM2,FTSJ3,USP34,CCDC57,ERCC1,NRAS,EHMT1,KIF15,WDHD1,MIER2,DIDO1,RAB22A,SMAD2,MID1IP1,RPS27A,MYO18A,MPV17,COX5A,SMAD1,ANXA11,SLC25A33,ZNF720,SEC61G,GGA1,MUM1,CCZ1,TRIO,RAB23,KCTD17,HAUS4,EIF2AK4,APH1B,PARN,CDC73,MYL6B,ATG4A,TMEM179B,ERV3-1,SMC3,C4orf3,GEMIN4,MVP,NUP85,PPP6R1,PABPC1,NSUN4,PPA1,IFRD1,AGGF1,FOXK1,RBM42,GTPBP4,MAP7D1,MRPL16,ELK1,EIF4H,RDH11,KPNA1,ETS2,TYW5,WIPI2,RUFY3,PDLIM5,ACSF2,RHOG,EXOC3,VTI1A,INO80E,SLC35B2,RCOR3,LCLAT1,CPNE3,KIAA1147,RBM23,ZNF420,AHCTF1,TBC1D22A,TBC1D14,NSFL1C,SEPT11,GPD1L,ZC3H3,ARL5A,PDCL3,SNX8,ERMP1,IDH3A,POLR2D,MEF2D,TMEM147,GSTCD,TANC1,MAT2A,VPS26B,NSMCE2,CORO1C,CAMKMT,PPP5C,PITRM1,TUBB,COMMD10,ZNF445,HABP4,CCM2,FLOT1,BTN3A1,ATG2B,GOLM1,ZBTB45,HUWE1,NAA50,ANXA5,LTN1,UBE3B,NAP1L4,ZNF710,ST8SIA2,SPTAN1,STAU1,TCTEX1D2,DDX24,TACC1,MRS2,LDHA,HEBP2,LLPH,C14orf132,RAB3IP,TTC33,PICALM,SH3BP5,SLC19A1,ACOX1,FAM3C,AEN,PARP10,YWHAH,FAM129A,TRIM11,YTHDC2,SNX15,NENF,SND1,RUFY1,TRIM65,ZER1,PRNP,KRR1,RAB8A,NUP210,NT5DC1,NOC2L,EIF5,TACC3,VPS13B,RYBP,PTPN18,MIOS,SNRPB,MBLAC2,CDC6,PBRM1,ODC1,USP21,TRAM2,FBXO28,ARRDC1,ADAM9,DVL1,NUMB,ZNF564,C1orf74,CTU2,PARP12,CENPF,LAMTOR3,CHCHD2,NCKAP1,LYRM2,RSAD1,TNS3,SUB1,RINL,KIF13B,MBD2,XPA,AHCY,RBM3,GLE1,LRSAM1,HDHD2,NTPCR,NSDHL,AMD1,CAMSAP1,METTL22,ICAM2,STYXL1,APPL1,RXRB,SDHB,PCM1,GALNT2,TMEM168,NLRC5,BTBD10,MYO9A,CCNB2,USP7,GLT8D1,RPLP2,SUCLG1,ARID2,TMX4,SLC2A1,ATP6V1B2,PCBP1,LYN,VAV1,TMEM69,MRPL50,PSMA6,ZNF473,ZNF302,BRPF3,TARDBP,BCAP29,CTDSP2,PRPF19,PPIF,KDM3B,MND1,CLCN3,BIRC3,RAB7A,ANKRD33B,PPIE,CHMP2B,VDAC1,EIF3H,TMEM201,GLOD4,IDE,DHX16,UHRF2,XRCC3,CHMP4B,PARD3,BCL2L12,C19orf53,KLHL21,PDAP1,TMX3,CDCA8,GTF3A,SLC12A9,TUBGCP2,DNAJB9,HOMER1,WBP1L,POLR1B,RBM15B,PPAN,RHOA,RPRD1A,BTAF1,TOP3A,ARHGEF12,PCGF1,DDX23,RAB18,TRIM26,PDCD6,ATP6V1D,L3MBTL3,FAM110A,NEIL3,CTBS,BBX,IMPDH1,TAF12,NR2F2,HIPK3,IFI16,TXN,NUP188,H2AFZ,PNISR,PRKCSH,USP39,UBE2I,SLC25A37,ASPHD2,RAB4A,TRA2B,TAF5L,CISD2,ZNF800,CDC5L,ZNF524,SGCE,OSBP2,NSUN2,USP22,CLNS1A,EIF3A,ZMYM3,DOT1L,IWS1,ANKRD10,WAS,KIF18B,TPP2,ZMAT3,B4GALT2,PRPF38B,RECQL,C9orf78,EWSR1,RRM1,ACAP1,B4GALT1,FAM136A,SUPT7L,TMEM165,CNOT3,NPLOC4,SPAG5,WDR48,RTKN,CEP104,EXOSC7,KLHL5,LRRC8D,MSH2,PIGG,FBXL7,OSTF1,SYTL3,FAM171A1,APOL1,GCC2,PRIM2,ELL2,RDH10,MFNG,GORASP2,CAPZA2,ADRB2,CCT8,MTR,PHF6,SLCO4A1,TTC13,GOLGA2,RBMX,MED15,PIAS2,APPL2,SAMD8,NUDT3,CDKN2A,ZNF511,ATXN3,RAF1,KIAA0232,C2orf49,CD320,EPM2A,CCNA2,MTMR4,BRI3,TP53BP2,AQR,RBM12B,ILKAP,CDK12,SAP30,BRD4,DRAP1,NARF,LRRC8A,ELP4,ABHD11,PKMYT1,ASB13,TRIM28,SUPT16H,EIF3K,CHMP4A,CBWD1,ATF6,PRPF4B,ADAM23,NDUFS1,MECP2,SECISBP2,HMG20A,WWP2,SLC25A36,JAKMIP1,CCNK,DNAJC8,ELP5,AXIN2,CITED2,JMJD4,KAT2A,RABIF,ADSL,PACS1,BMS1,KCNQ1,OTUD3,ARSK,MACF1,KIF11,KLF6,SMAP2,FADD,SH3GLB1,MYO1F,CBX3,TMEM127,PPP1R11,DDX5,WDR62,TAF6,ESPL1,DDB1,DEF6,FAM83G,IPO4,UBL3,PIGM,NAT9,LYRM4,GPR132,UBE2Q1,PTP4A3,BRIX1,MRPL19,ZNF696,SF3B2,PCYOX1L,CDC42,SYNM,GOT2,JAZF1,HADHB,RPF2,SLC35C2,CNNM3,CARM1,SRPK2,WDR41,LARS,ZCCHC10,CCDC138,LRBA,TMEM216,SUMF2,KMT2C,OGFR,PRPSAP1,ASF1B,RPL37,MAN2A2,EIF4ENIF1,NIP7,U2SURP,MIA2,ZNF268,VPS4A,ATP6V0E1,PPP1R2,PM20D2,XPNPEP3,RGS2,LYAR,FAM89B,POLR2I,TRAFD1,SUGP2,GBA,EIF2A,SYVN1,CCDC71L,DAPK3,ARHGAP15,MASTL,UAP1,NFIL3,FN3KRP,YWHAZ,CTSA,TMEM14A,TSEN15,ADNP2,TCF12,PRKAB1,MDH2,SMARCA4,ORC1,RRN3,UBXN2A,IARS,KIF14,EXOSC1,CS,CLTB,DNAL4,CSTF1,POU2AF1,UBQLN4,NXT1,PGGT1B,SELPLG,SMU1,ATXN1,GLO1,OGDH,BICD2,CADM1,EDEM2,HERPUD2,TOLLIP,FANCE,MBD3,PDHX,RPS9,ALKBH6,SURF4,DUS3L,ARNTL,ANP32E,FKBP5,TMEM101,CCDC125,ABCA1,PDCD2L,GCLM,RAE1,DCTN2,NUP54,CHIC2,PAWR,MXD4,DCUN1D4,PIP4K2A,XPR1,FERMT3,KIF5B,KLHL20,SEC24C,RRBP1,ARHGEF2,ANP32A,LDLRAD3,C12orf75,STAT3,MYO5A,NIPAL3,TXNL1,DCAF6,FAM49B,TMEM39A,RFFL,COG1,RCOR1,PRMT2,TFEB,LEMD2,SERF1B,UPF1,ELMO1,ZC3H7B,DTX4,ZMIZ1,TERF1,HRAS,CCDC93,FGFR1OP,TMED7,PIGQ,CNTROB,PPP1R16B,GSDMB,TTC9C,PDS5B,NUP153,SENP1,PGAP2,TMEM115,PLEKHM3,DCUN1D5,PWWP2B,TRIM47,WDR11,AXIN1,SMG9,TRIM52,LONP2,NDUFV2,PHF23,CERK,SLC4A2,EZH1,ITGB5,LMNA,MCTS1,DDX56,EIF2S2,SLC38A5,FOXN2,CARS2,PRRC2A,C16orf72,RB1CC1,ZMYND11,PGS1,MYBL2,UHRF1BP1,MPG,MATR3,CYB5A,NCDN,SETD3,TEX30,PTAR1,CNOT6,NDE1,EGLN1,ZNF207,ANKRD27,PPP1R37,ABCA3,SARNP,IVNS1ABP,MON1B,NIT2,NUF2,ZNF267,TCF19,TMEM161B,KTN1,APP,PRKD3,CLUAP1,ATP2A2,UTP18,GRSF1,ZCCHC2,RNF19A,FAM76B,CLN6,TMEM9,GCC1,RNF169,ADCY7,ATP6V1G1,RNPS1,CDCA2,GPR137,DDX17,CHCHD3,PEX5,CDC16,HIPK2,MBOAT1,TICAM1,PDXK,ZBTB11,ANXA6,TMBIM4,GMCL1,UBE4A,IL21R,ETS1,WRB,ZNF92,PNO1,CAPN2,ADD3,SUV39H2,TTLL12,TMX1,HNRNPM,MFSD12,LDHB,PPP3CA,NUDT8,POLK,EMP3,MTMR12,ZP3,PDE3B,KIF18A,CCDC6,WNT5B,MAPK6,C4orf46,LY75,SLC25A19,RGL1,PSAP,WDR76,IGBP1,FAF1,SNAPIN,COX15,AGRN,THOC1,GNPDA1,GPBP1L1,PPP1R15B,CSNK2A1,GIT2,BIRC2,ATPAF1,DLG5,ABL2,XRCC2,ZFYVE27,MCMBP,PTPRK,CDC37,METTL1,HARS,GMFB,ESYT1,ANLN,RAB5B,RHEB,DPYSL3,TBC1D17,CDCA4,TONSL,NRM,NAGLU,ACTB,ZNF45,TMUB1,CTCF,ASAH1,DOCK11,CRLF3,LRRC14,NUS1,SLC27A4,MDFIC,MAML1,CYTH1,NQO2,UTP15,EIF2AK1,EIF4G2,ZDHHC3,MOSPD3,ITPRIPL1,CDC27,SNAP23,TBPL1,PRMT7,KCTD7,NDUFA5,CYLD,UGP2,COPE,HCFC1R1,ZADH2,GGPS1,RPAIN,RAD23A,ATP6V0B,PDK2,STRBP,DUS4L,PDCD2,SAP30L,SLC39A9,CLPTM1,DNAJC9,MTMR6,NFATC2,KDM1B,ARL5B,USP36,CCDC127,MRPL2,ATP1A1,PSMD3,CEP55,NDUFA11,DNAJC17,ZNF436,NCOA1,SLC25A39,ZC3HC1,ATXN7L2,CDC40,GOLIM4,RRP15,DAP,GNE,SMC6,ARFIP2,NKRF,BZW2,WRNIP1,TMA7,SS18L1,CENPM,PTGES3,CAMK2G,MLEC,ZNF202,PPWD1,RHOT2,NEU1,TPD52L2,GOLGA7,TWSG1,GLG1,PGRMC1,FAM126A,RPS6KC1,UBE2C,PPCS,NDUFB6,TMEM41B,ZDHHC8,PLXNA1,CCNB1,SLC20A1,COMMD6,ABHD14A,POLR3K,ASAP2,SNUPN,CNPY4,PLCL2,TFG,SEH1L,ATG9A,PBK,MKI67,DDX20,AMDHD2,SLC17A5,GALNT7,CCNF,FOXRED1,RBM47,PTER,WDR4,DHTKD1,TRAF5,HDAC2,PWWP2A,HSPH1,LIME1,MAPRE1,CHTF18,ADO,KIF23,SLC35B1,NOTCH2,PMF1,JMY,FKBP1A,SLC31A1,SNX18,ATIC,CTPS1,ATP6V0A2,PIKFYVE,RNF135,LPCAT1,EEF1D,TMED2,FTL,DDX28,PIP4K2C,FAM133B,RIT1,PLEC,KDM3A,SF3A2,FAS,EPRS,ZNF777,TMEM54,QARS,TCOF1,CABLES1,NRBP1,DNMT3A,RWDD1,CKLF,TRIP10,SF3B1,CAST,SUZ12,RPS6KA1,RAC1,GPR89A,OLA1,GNB2,FLAD1,APLP2,KDM2A,TNPO2,CDKN1B,TALDO1,GPX4,ATP13A1,MAPRE2,ERF,CUL3,SLBP,KIAA1586,H2AFV,GAR1,PSMB9,POLG2,DHX57,NSA2,HSPA4,JAK1,GOLGA8A,TBL3,SEL1L,H2AFX,KLHDC4,B4GALT3,PDCD11,ATMIN,POLQ,OTUD5,NCOR2,ANKRD13D,PKP4,SCAMP3,BABAM1,CDCA3,SLC25A12,BLM,TMCC3,GTF2F1,CRAT,AHSA1,PRC1,UPF2,COPS7B,SLC38A10,CNPY3,UBE2M,IFT46,TSHZ1,ZFP64,STRIP1,DENND4C,WDR18,ILF3,LRRC1,RHOT1,MARK2,TSR2,ECH1,PRDX1,PLD3,NUCB1,FBXO21,GNA12,C1orf131,PRDX3,PFDN4,HNRNPH3,TFDP1,STX18,KHSRP,ASNA1,SSSCA1,VPS29,BYSL,S100PBP,MIB2,PTMS,NOP2,UBN1,DCAF15,NF1,ALKBH5,UBE2Z,TAF6L,MAPK14,BECN1,SNAPC4,RNF103,BCAT2,MBD4,C18orf32,METTL14,ZNHIT6,IMPAD1,RCSD1,PHTF1,SRI,KIF22,ZBTB22,NFU1,OGG1,TRIM14,ELOF1,COPS8,FYTTD1,TRIM8,RRM2,ABHD5,UBTF,CXXC4,PAF1,SPATA2,PQBP1,IARS2,ATXN2L,GALNT10,STARD3NL,RPS15,PIGN,AGTRAP,CIB1,XPO7,SRRT,ZNF449,CAPZA1,GLTP,BCL2,KIFAP3,N4BP2,HP1BP3,VOPP1,THNSL1,ISG15,CAND1,GNAS,TSC1,RBM25,ZFP90,RBBP4,ZBTB24,SMARCD1,MBD1,WASF2,MMACHC,TOMM20,IFI27L1,GNPNAT1,MPHOSPH8,HNRNPUL2,CHD1,MEAF6,C2orf68,CCDC50,AKAP8,PARL,RPN2,CHTOP,F2R,FAM3A,TMEM14C,ABI1,HTRA2,MOSPD1,RLIM,FAM172A,ZNF500,PSMB7,NLN,WIPF1,BUD13,NDUFB1,PEF1,EIF3G,BTBD1,TAB2,TULP3,WDR59,CANT1,SCARB1,GAS2,USP11,SMURF1,TSPAN5,CDS2,MAGEH1,EYA1,MRPS26,LETMD1,KLF13,RGS1,HDDC2,MAN1A1,FBXO5,GART,TANK,PELO,BRD7,MRPL11,SAMD4B,ZDHHC18,GTF3C6,POLR3GL,WDR81,MEN1,ZNF407,MFN2,COX8A,MBD6,SRSF3,IDH3B,TATDN1,ATP6V1C1,TSC2,LACTB2,CMTM6,ZNF275,ANKRD39,RPL23A,CDKN2C,NAPG,USF1,DNAAF2,MECR,AP1M1,UPRT,ECD,TIPARP,LRRC59,ANKRD9,RHBDD2,MGAT5,BAK1,ZNF559,RHOBTB3,GABPA,WBP1,NUTF2,ARF4,GINS4,KRIT1,BOLA3,AHNAK,RAD18,PDRG1,RNASEL,CHPF2,OAZ1,PDCD4,SMNDC1,NXT2,HIVEP3,KIAA0100,CLSPN,RHOC,DHX9,PDCD7,PSMD9,HAUS2,COPB2,TFAP4,CD59,RIMS3,MEGF8,EFTUD2,FBXO7,MRPL21,LUC7L2,EIF3L,MTA2,TYW1,USP10,ITM2A,SSR2,MTX1,SFXN5,FNTA,PDLIM1,TXNDC16,ZNF830,TMEM159,MRPL3,ALS2,TRIM41,NQO1,POC1A,ANK3,PTTG1,TPX2,TBC1D13,GLRX3,STMN1,REPS1,CBWD5,ABHD16A,FBXL6,SH3BP1,MTA1,UBA5,CLCN6,INTS12,RPRD1B,CPNE1,SEC61B,FAM118B,GOPC,E2F3,CIRBP,RPL38,CRNKL1,PFKFB3,GORAB,RAB1A,GIGYF1,TMEM184C,PPP2CA,KIF2A,CCDC14,LSM6,RNF38,SNRPG,DMWD,USP13,MZT1,ZFP91,TRMT6,IP6K2,WDR5,SLC25A43,PMVK,IFT27,NEIL2,RRP36,SRXN1,RPA2,PSMD2,CLIC4,PDCD10,CBWD2,COQ4,ITGB8,ARF5,ARHGEF1,FBXL19,GTF2H2,TTPAL,UTP20,MAGT1,CD81,TMEM131,WDR13,FANCI,PAPOLA,CREM,TET3,FANCL,GLIS2,IL6ST,INTS1,POP7,SLC44A1,MTPN,ASB6,PLK1,CELSR2,SEPT9,RBX1,APH1A,CKAP2L,PSMG1,EAF2,IL12RB1,KRTCAP2,LUC7L,LSG1,NECAP2,ALG3,TRIM4,AGPAT2,CHD3,ZNF367,PRPF4,KPNA2,BEND6,CLN3,DNAJC30,FAM208A,NGLY1,POT1,CCDC137,RMND5A,HJURP,PHB2,DNAJB2,FAM53C,NKD2,SDC2,KLC1,CDK13,ADCK5,COX4I1,DNAJB1,RAB6A,ARID1B,C1GALT1,MLX,UBE2Q2,CCP110,ZNF746,ARL6IP1,CTR9,NIPSNAP1,ABHD2,DCAF8,ACSL3,LDB1,MAP4K3,RBM38,NMT2,IRF5,HAUS8,MBIP,ORMDL2,COX7A2L,ZDHHC7,SIL1,DTD1,UNC13C,SART1,TRAF7,NDUFAF2,TOR1AIP1,LAGE3,TM9SF3,ZFYVE21,RRAGC,OIP5,NRF1,WDR44,PPME1,EFCAB11,RPAP1,CABLES2,LMAN1,AHCYL1,TOP1MT,STRAP,SPSB3,ZNF583,SNX25,POLR2G,KIAA0040,ZNF780B,PPT1,NUP155,DCLRE1C,MRPS14,RHBDF2,SUGP1,RBL1,FASTK,UBXN2B,STK38,AP1S1,SLC22A23,H3F3A,CHID1,SMAD4,SLC30A9,CMAS,UNK,NADSYN1,HMGN3,NCAPG,SCYL2,FZD6,HERC3,GTPBP3,CTSS,ORC3,RNLS,YTHDC1,ACP2,HMGN5,CSRP1,ABCF2,TUFM,RANGAP1,PNPLA8,HAGH,API5,ZFR,SEC23IP,E2F1,TMEM219,USP20,RBPJ,PDCD6IP,MAX,GXYLT1,LUZP1,ADAM10,CXXC1,TSC22D3,AP3M2,CUL1,GYG1,NANS,OAT,MYEF2,ANKRD26,NOL11,FIZ1,ZNF200,SLC26A2,SRP72,KLF10,LACTB,CBFB,RFC2,RAB2B,PRIM1,MAP3K4,HHEX,LUC7L3,RPS14,MAP4,BTF3,PTPDC1,NMD3,PTOV1,DNAJC5,SCOC,DHPS,POLR2K,ANKH,VAV2,PRKAA1,C16orf87,TATDN3,DLGAP4,PXMP2,PSEN1,ZNF79,PDXDC1,VPS25,NDUFS7,YY1AP1,C12orf10,FAM192A,RPN1,LHX8,ARPC5,ZNRF2,TPST1,DAPK1,PIK3IP1,CYC1,SOCS5,FDFT1,PIGT,EMB,ZNF574,C1orf35,EXOSC9,ARID1A,PTTG1IP,C9orf40,FXR1,GOSR1,MAP2K2,TWISTNB,AKAP1,XRCC5,HMGN2,PI4K2A,CAT,DERL1,HSPBP1,ARAP1,USP32,FAM83D,CABIN1,SMPD4,GPI,CYTIP,TP53RK,RAB11B,UROD,SLC39A13,BCL2L1,NUDT19,DECR1,RALB,ADCY9,LPIN2,MRPS27,SOCS6,TTC3,RNASEH2A,ANKLE2,CDC123,OAF,VDAC2,EDF1,ERC1,AMZ2,ANKZF1,RAD51C,ZNF282,DSN1,DDOST,HINT1,DGCR8,SAFB,HAGHL,RWDD4,LMBR1,NCLN,BEND3,EYA2,DYNC1LI2,MANBA,B4GALT5,SLC41A1,FAM76A,TKT,CBLL1,ARGLU1,LANCL1,POFUT1,FAM8A1,HEATR5B,HLA-A,EBP,RFWD3,NDUFA2,FJX1,FUT8,BTF3L4,PTPN11,MRPL54,FEM1B,RPL19,CNN2,NDUFA3,MTX2,MSH6,PDLIM2,LONRF3,RFXANK,FBXO9,GUF1,RPL32,ZHX1,OAZ2,NDUFS5,WDR91,POLA2,ZNF76,MTX3,COPA,UQCR10,PHRF1,HMGXB3,ABCB10,MAP1LC3B,DST,RAB35,SIVA1,GPATCH1,TCEA1,DEAF1,SNRNP200,LAP3,NCK1,VHL,SREK1,ARHGDIB,PITPNB,HSPB11,BRWD1,PPM1G,SH3GLB2,BAZ1B,ACBD4,STK11,CLU,CHEK2,ZSWIM3,TSTD2,MRPL13,CHPT1,DCAF5,CAPN1,UBE2D3,NSMCE4A,PPP1R12A,ZCCHC8,GORASP1,PCSK7,EPN1,THRAP3,QSOX2,TTF1,NUP205,PRPF18,CHKA,DTL,MED10,ZRANB1,SLC12A2,ATP6V0D1,CSNK1G3,CREG1,NUDT4,VKORC1,SLTM,EVC2,KLHL15,SIAH2,SLC16A1,EHD4,SNRNP70,APOL2,N4BP2L2,CHMP2A,CORO7,FEZ2,UCK2,PMS2,CLCC1,EXT2,MXD1,USP5,HNRNPA2B1,NVL,CYB5R1,ZNF770,EBAG9,RNF25,PCGF6,PON2,HNRNPR,STAT6,HPS5,MAPK1,BRD9,TMEM33,NAT14,DNAJC2,TRIP12,SCYL1,VPS45,MYO9B,GFM2,SPPL2A,FASTKD3,FGFR3,MZT2A,PPIG,ZDHHC13,TMEM99,H2AFY,NDUFS8,ATG13,ERI3,FBL,SLC35A1,FRMD8,MICAL3,TGFB1,ELOVL5,HEMK1,TIMMDC1,HELB,PSPC1,SCFD2,NDRG3,CDK11A,MEGF9,ACAT1,CENPT,PLOD3,RAB3IL1,ZSWIM6,RAB14,ADD1,KDM4A,MRPS15,XIAP,DHX8,GLUD1,ANKRD23,PABPC4,CDK5,CALM2,PSMD1,NSRP1,RABGAP1L,SRSF4,FNIP2,KCNAB2,PCBP2,PLK3,ZNF672,MRPL43,MCL1,PPFIA3,SMC2,ICMT,LIMK1,ZNF689,PRDX5,ATE1,MLYCD,ST3GAL2,ATP6V0C,FBXL3,E2F2,PFKP,AAAS,DDX42,SSRP1,MRPS2,STRN4,TOP2B,ZNRF3,TMED3,DDRGK1,RAVER2,GNS,INTS7,INPP5A,MCM5,PHF14,ZNF326,UBE2QL1,NAGPA,TSPYL4,DHX29,TEX10,MAN1B1,RPS10,CBFA2T2,ABCF1,RHOB,LRRC14B,DTWD1,PTPRF,SCARB2,OSBPL11,CCDC86,DUSP3,HEXA,RNF139,SNX14,TRERF1,UBR2,CHD1L,ACTR3,WDTC1,MYH9,CREBL2,NIPA2,PRKACA,SAFB2,ANKIB1,STAM,ARL6IP6,RAB21,SP100,ZKSCAN1,DDA1,NUP107,ANKRD13C,MAVS,CEP63,ATF2,RBM15,DCTN1,SHOC2,PSRC1,MAP4K4,WBP2,ATP6V0A1,NUSAP1,NDUFA7,DNAJA1,TAF2,C19orf54,SEC61A1,WDR7,CBLN2,FUS,LRP8,COIL,LRCH1,GALK1,ZNF786,RPS2,SESTD1,TRAK1,SIKE1,AKT1S1,KRI1,FBXO3,ERH,GATC,NDUFB4,PPP1R8,PRDM4,GTSE1,GEMIN6,DCP1A,SGCB,IMPA2,NUDC,PDPK1,TK1,TNFAIP3,GALC,ZNF512,KIAA0930,MRPS10,DDX39A,RPA1,ZNF862,ZNF180,KEAP1,POLE,TATDN2,PITX1,CAPN7,LRPPRC,PML,HMGB2,USF2,ANAPC4,SRM,DDX47,MCCC1,CDC42SE2,S1PR2,CDIPT,SEC16A,SSR1,LIN9,PCNA,ZNF639,TRMU,ETV6,PIK3R2,TXLNA,PPCDC,FAM86C1,MYBL1,CCAR1,MRPL32,ABCC5,PBXIP1,TLK1,MRPL12,EZR,LNX2,LRP5,BRCA1,PRKRA,STX16,EPB41,OPTN,SEPT1,SOCS4,QRSL1,PIEZO1,OSGEPL1,GLCCI1,NUDT11,NAA60,SEPHS2,LZTR1,RACGAP1,PPP3CB,B4GALT4,RLF,RAPGEF6,SNRNP25,RB1,VASP,VMP1,MEA1,TIMELESS,AHDC1,ALDH18A1,TMEM8A,PREB,ABCC1,TRAPPC9,AACS,MEMO1,KRAS,UBE4B,NFATC2IP,LY6E,ARPC1A,ZNF174,PSMC4,GOLGA4,PALB2,SYNCRIP,PRPS2,NIPA1,TIGD2,RNF114,FOXM1,MRPL39,XAB2,SUMO2,DUSP22,COMMD8,RPL11,CSDE1,MDM2,CORO1A,METTL9,MINPP1,POC5,DVL2,GM2A,PSMA8,COQ10B,CPOX,TIGD5,SLC26A6,CYP20A1,PRPF3,TXNL4A,RPSA,SRSF1,DNAJC10,ZNF700,SCAP,TIMM17A,TOMM6,LTA4H,AP2S1,USP53,INTS2,CTDP1,MIF4GD,CDT1,ARID5A,SUMF1,GGA2,CSNK1A1,AP3S1,RMI1,TFRC,PTPN2,IRF4,STARD9,NDUFV1,SLC1A4,CWC27,SLC35B4,DDX31,ABCD1,RPAP3,CNTN5,SNX2,ZMYM5,CCDC34,CHCHD6,BSDC1,FBXO41,KPNA4,BIRC5,TFE3,SNAP29,CDCA7L,PKD2,CHMP7,SAT2,GCSH,ZNF496,TMEM109,TAP1,YTHDF3,NHLRC3,IKBIP,ELMOD2,KIFC1,DBNDD1,CYB5RL,PARPBP,CDC25B,PRADC1,DNMT1,NOL12,ORAI2,AKT2,NOL8,GNG7,AURKB,MCFD2,SLC25A5,ZFAND5,MAK16,STT3A,TMED10,PSMD8,EIF2D,ITGB1,UQCRH,RRS1,ARRB2,RTN3,ZNF598,DDX58,WSB2,PPIB,MUT,GMFG,HLA-E,NDUFA4,MAN2B1,METTL3,CFLAR,NDUFS4,RNF121,MEX3C,KLF16,HDAC7,DAD1,BDH1,PCYT2,GNAI2,ANKHD1,MORC3,TERF2,KCTD20,SEPT8,DCTD,PKM,TOMM40,PATL1,ADSS,SERF2,ZFP92,NSF,DCK,ERGIC3,ACLY,LPCAT4,VCPIP1,PPP6R2,MAP3K5,YY1,CDK2,RNF14,ZC3HAV1,SYS1,ZBTB37,URB2,EIF3D,MAGED1,KLHL18,ADPGK,SLC25A44,AP1B1,SDHA,PAIP2,PHC2,CRKL,TERF2IP,CYHR1,ZNF75D,SHC1,UCHL5,NAA35,TMBIM1,CCT2,MKLN1,LYRM1,GALK2,CDC23,SHCBP1,AP4E1,PRDM11,VEZF1,PPP2R5A,ACYP1,STAT1,PPA2,TRIM32,RHEBL1,C1orf112,TCF3,MRI1,BRAP,AGPAT3,MYNN,SPR,RAB11A,REEP5,FOXO3,MAD2L2,CCDC28A,RBM17,MAT2B,PTEN,CENPJ,OSTC,CREB1,NCOA2,PACS2,SMC4,NEK7,NET1,PARP4,TBRG4,ANAPC2,YIF1A,SGSH,HGS,TTLL4,SLC38A7,MFAP1,CCDC69,BRWD3,ESYT2,SKA3,NPHP4,UBE2E2,HNRNPAB,PLXNC1,TMEM184B,ST13,DNAJC24,ZNF107,SLC29A1,KIF2C,AGFG1,SIRT2,USP48,SNRPD3,UBQLN2,FKBP2,CUTC,EDC3,UBLCP1,ZNF804A,RAP1A,THADA,EIF4A3,AP3S2,ATG3,DPYSL2,PPP1R12C,AKR1B1,JOSD1,NDUFB9,RP2,TTC4,TECR,ARID4A,FGFR1OP2,TIMM50,TDP1,DPM1,FOPNL,SLC16A7,SLC25A22,STK17B,DHX15,CHAF1A,GEMIN5,COPS6,SASS6,PSMC1,SLC12A7,TBC1D12,MED13L,TIA1,MEF2A,EPHX2,PITHD1,RHBDD1,BANF1,ZNF335,BUD31,YBX1,KNTC1,UBE3C,ACAD8,ZNF189,KDELR1,TSTA3,CIC,OXR1,SEPT7,NAP1L1,ODF2,EXOC4,NUP62,PITPNA,KIAA1328,NAA20,PTDSS1,PDSS2,C7orf26,TMEM106C,IMMT,ASH1L,CHERP,WDYHV1,PLAGL2,IRF3,CHKB,TWF2,PAIP1,ANKRD28,FARSA,ANKLE1,SAR1A,SCAMP4,APOOL,PDIA6,ACSL5,TOR1AIP2,AZI2,GFER,RAD54B,TMEM41A,DAP3,ZNF317,GADD45B,AKNA,REEP4,CBX4,KIF3B,GOLPH3L,SH2D3A,CASP6,TOR3A,SRGN,DBF4,SAC3D1,CTNNBL1,CLDND1,TTC17,SLC25A1,GINS1,PAQR6,CSNK1G2,TELO2,HMGN1,ADAM17,NASP,ASPM,PPP1R21,PRKAR1B,SYMPK,TARS,SNRPA,MAPK3,HSPA1B,HLA-B,PLAA,ATAD2,ZNF330,OSBPL8,KBTBD7,PREPL |
| 3.840e-02 | -3.26 | regulation of protein export from nucleus | biological process | GO:0046825 | 41 | 11 | 17256 | 2622 |
CDK5,TXN,MDM2,SP100,PTPN11,GTSE1,RANGAP1,PRKACA,PARK7,ZC3H3,IWS1 |
| 3.842e-02 | -3.26 | GSE27896_HDAC6_KO_VS_WT_TREG_DN | MSigDB lists | GSE27896_HDAC6_KO_VS_WT_TREG_DN | 155 | 32 | 17377 | 2626 |
DDX58,BCCIP,KCTD7,COMMD10,NPHP4,TMEM41B,DAP,NIT2,WRB,PNO1,HERC3,CLIC4,EFTUD2,NUP107,BCAP29,FDFT1,NIPSNAP1,RFC3,EID1,PPT1,AMD1,DNAJC9,ITM2A,EXOSC9,UTP3,GAR1,CCT8,CLNS1A,SH3BP5,DTWD1,AGPAT2,BYSL |
| 3.844e-02 | -3.26 | establishment or maintenance of epithelial cell apical/basal polarity | biological process | GO:0045197 | 46 | 12 | 17256 | 2622 |
DLG5,PDCD6IP,RHOA,CDC42,SH3BP1,WDR1,EZR,ERBIN,MYO9A,MARK2,ARF4,PARD3 |
| 3.848e-02 | -3.26 | 90S preribosome | cellular component | GO:0030686 | 32 | 9 | 18223 | 2701 |
KRI1,UTP20,CMSS1,UTP18,TBL3,NOC2L,BMS1,RPSA,RRP36 |
| 3.849e-02 | -3.26 | CTLH | prosite domains | PS50897 | 10 | 4 | 12060 | 1670 |
GID8,RMND5A,MKLN1,SMU1 |
| 3.849e-02 | -3.26 | ADF_H | prosite domains | PS51263 | 10 | 4 | 12060 | 1670 |
GMFG,TWF2,CFL1,GMFB |
| 3.849e-02 | -3.26 | CYCLINS | prosite domains | PS00292 | 10 | 4 | 12060 | 1670 |
CCNA2,CCNF,CCNB1,CCNB2 |
| 3.849e-02 | -3.26 | RNA polymerase II transcription cofactor activity | molecular function | GO:0001104 | 103 | 23 | 17224 | 2647 |
POU3F2,POU2AF1,TRERF1,DHX9,WBP2,SMARCA4,MED13L,MEF2A,THRAP3,DNAJB1,BRCA1,SOX4,TRIM28,MED8,MED10,HIPK2,MED15,NCOA1,CITED2,BEND6,CARM1,N4BP2L2,MED22 |
| 3.850e-02 | -3.26 | mitochondrial intermembrane space | cellular component | GO:0005758 | 79 | 18 | 18223 | 2701 |
TIMM8B,NDUFS1,CPOX,NLN,CHCHD2,CYCS,COA7,LYN,GFER,PARK7,STOML2,CAT,TIMM13,TIMM23,TIMM29,MICU2,NDUFS5,HTRA2 |
| 3.854e-02 | -3.26 | SET | smart domains | SM00317 | 38 | 10 | 9493 | 1367 |
KMT2B,NSD3,ASH1L,EZH1,KMT2C,KMT5C,SUV39H2,KMT2E,KMT5A,EHMT1 |
| 3.856e-02 | -3.26 | regulation of cellular component size | biological process | GO:0032535 | 358 | 67 | 17256 | 2622 |
RHOG,ADD1,RAC1,ACTR3,WDTC1,PLXNA1,TWF2,CDK5,VAV1,RAB21,SH3BP1,DPYSL2,CLCN6,DNM2,ZFYVE27,CORO1A,MTPN,CARMIL1,CFL1,MLST8,CLCN3,LARS,NCK1,GMFB,LRRC8A,WIPF1,EZR,RAB22A,CLNS1A,WAS,E2F4,LIMK1,SLC12A7,GMFG,VAV2,ARFIP2,NCKAP1,AKT1S1,ARF1,SLC12A9,RAB11A,JMY,PDXP,VASP,PTEN,ARPC5,MEGF8,CAPZA1,CREB1,SLC12A2,HP1BP3,SPTAN1,IFRD1,CYFIP1,RHOA,RB1CC1,WDR1,ANAPC2,CAPZA2,ARPC1A,MACF1,PICALM,TSC1,GOLGA4,LAMTOR4,RUFY3,ALS2 |
| 3.858e-02 | -3.26 | Lima1 (LIM domain and actin binding 1) | protein interactions | 65970 | 129 | 29 | 17029 | 2761 |
PPP1R18,ADD1,PPP1R12A,LUZP1,PHB2,WDR1,DCTN2,SMC2,PLEC,CAPZA2,SEC16A,PICALM,GNAS,INF2,UBXN2A,NAP1L1,AHNAK,ADD3,CDC42,ARPC5,CORO1C,MYO18A,CAPZA1,NAP1L4,CLTB,NDE1,CFL1,MYO5A,SPTAN1 |
| 3.861e-02 | -3.25 | Naa11 (N(alpha)-acetyltransferase 11, NatA catalytic subunit) | protein interactions | 97243 | 25 | 8 | 17029 | 2761 |
PHC2,DLG5,GOLIM4,UBR2,NAA50,NLN,CCDC71L,CDKN2A |
| 3.861e-02 | -3.25 | BTF3L4 (basic transcription factor 3 like 4) | protein interactions | 91408 | 25 | 8 | 17029 | 2761 |
TPD52L2,ARPC5,GOPC,NACA,TXLNA,ADSL,BTF3,DCTN1 |
| 3.861e-02 | -3.25 | HADH (hydroxyacyl-CoA dehydrogenase) | protein interactions | 3033 | 25 | 8 | 17029 | 2761 |
CLIC4,UBA5,STAT1,PSMA1,PITPNA,FKBP2,APP,MAPK3 |
| 3.861e-02 | -3.25 | C16orf71 (chromosome 16 open reading frame 71) | protein interactions | 146562 | 25 | 8 | 17029 | 2761 |
CREB1,ARRB2,DUSP3,MCMBP,PRPSAP1,SEH1L,PTOV1,PIP4K2C |
| 3.861e-02 | -3.25 | HPF1 (histone PARylation factor 1) | protein interactions | 54969 | 25 | 8 | 17029 | 2761 |
TFAP4,HMGN1,TXN,MKLN1,HMGN4,H2AFY,H3F3A,HMGN2 |
| 3.861e-02 | -3.25 | EIF2D (eukaryotic translation initiation factor 2D) | protein interactions | 1939 | 25 | 8 | 17029 | 2761 |
HNRNPR,HARS,HEXB,CUL3,WDR5,EIF1B,DHX15,CDC5L |
| 3.861e-02 | -3.25 | FOXO4 (forkhead box O4) | protein interactions | 4303 | 25 | 8 | 17029 | 2761 |
USP7,MDM2,ATXN3,AKT2,PIN1,OGT,YWHAZ,SMAD4 |
| 3.861e-02 | -3.25 | BRMS1L (breast cancer metastasis-suppressor 1 like) | protein interactions | 84312 | 25 | 8 | 17029 | 2761 |
BRMS1,FOXK1,PHF23,RBBP4,SINHCAF,HDAC2,MXD1,SAP30 |
| 3.861e-02 | -3.25 | PCDHB15 (protocadherin beta 15) | protein interactions | 56121 | 25 | 8 | 17029 | 2761 |
DERL1,SLC25A19,NAP1L1,NANP,AP3S1,PRDX5,HLA-A,GPATCH4 |
| 3.861e-02 | -3.25 | HIST1H2BL (histone cluster 1 H2B family member l) | protein interactions | 8340 | 25 | 8 | 17029 | 2761 |
TONSL,MCM5,VHL,DNAAF2,CUL1,MCM2,CD81,CAND1 |
| 3.861e-02 | -3.25 | URB2 (URB2 ribosome biogenesis 2 homolog (S. cerevisiae)) | protein interactions | 9816 | 25 | 8 | 17029 | 2761 |
ZNF512,RBM34,MECP2,NOL8,RBM4,CCDC59,IFI16,LMNA |
| 3.861e-02 | -3.25 | NSMCE2 (NSE2 (MMS21) homolog, SMC5-SMC6 complex SUMO ligase) | protein interactions | 286053 | 25 | 8 | 17029 | 2761 |
SMC6,EWSR1,SMC3,SYNCRIP,TM9SF4,TXLNA,NIPSNAP1,PDS5B |
| 3.861e-02 | -3.25 | PABPC3 (poly(A) binding protein cytoplasmic 3) | protein interactions | 5042 | 25 | 8 | 17029 | 2761 |
GALK2,BRIX1,MCM2,ARRB2,APP,ZC3H3,ZNF746,PAPOLA |
| 3.861e-02 | -3.25 | DMTN (dematin actin binding protein) | protein interactions | 2039 | 25 | 8 | 17029 | 2761 |
ACTB,YWHAZ,NUP188,GOLGA2,PRKACA,APP,DYNC1LI2,PTOV1 |
| 3.861e-02 | -3.25 | KIF5C (kinesin family member 5C) | protein interactions | 3800 | 25 | 8 | 17029 | 2761 |
KIF5B,HOMER1,TRAK1,ILF3,CSNK2A1,KLC1,CUL1,SNAPIN |
| 3.861e-02 | -3.25 | MMS22L (MMS22 like, DNA repair protein) | protein interactions | 253714 | 25 | 8 | 17029 | 2761 |
TONSL,H2AFX,UPF2,MCM2,BLM,ASF1B,SUPT16H,SSRP1 |
| 3.861e-02 | -3.25 | GOT2 (glutamic-oxaloacetic transaminase 2) | protein interactions | 2806 | 25 | 8 | 17029 | 2761 |
MDH2,GLUD1,GYG1,GPI,FUS,MPG,PREPL,CDK2 |
| 3.861e-02 | -3.25 | TSKS (testis specific serine kinase substrate) | protein interactions | 60385 | 25 | 8 | 17029 | 2761 |
FNTA,PGGT1B,POC1A,FAAP100,USP10,APP,SPAG5,SNAPIN |
| 3.861e-02 | -3.25 | BCKDHA (branched chain keto acid dehydrogenase E1, alpha polypeptide) | protein interactions | 593 | 25 | 8 | 17029 | 2761 |
BOLA1,SPRYD4,ATP5F1A,LYRM4,FAM136A,PTEN,COQ10B,CUL3 |
| 3.861e-02 | -3.25 | MARCH7 (membrane associated ring-CH-type finger 7) | protein interactions | 64844 | 25 | 8 | 17029 | 2761 |
UBE2D3,USP7,PPP3CA,PPP3CB,UBE2M,TRIM65,UBXN1,VAV2 |
| 3.861e-02 | -3.25 | ZMIZ1 (zinc finger MIZ-type containing 1) | protein interactions | 57178 | 25 | 8 | 17029 | 2761 |
NFATC3,BCLAF1,RBPJ,BRCA1,MAML1,ETS1,TRIM28,SMAD4 |
| 3.861e-02 | -3.25 | PRCP (prolylcarboxypeptidase) | protein interactions | 5547 | 25 | 8 | 17029 | 2761 |
PPP1R2,LDHA,NUTF2,TOMM40,PGAM1,KCMF1,NCDN,LDHB |
| 3.861e-02 | -3.25 | ORF50 (transactivator) | protein interactions | 4961526 | 25 | 8 | 17029 | 2761 |
MDM2,TRIM26,SUMO2,CTSA,EIF2A,RBPJ,UBE2I,NCOA2 |
| 3.862e-02 | -3.25 | mRNA Capping | REACTOME pathways | R-HSA-72086 | 29 | 9 | 10287 | 1696 |
POLR2I,POLR2G,POLR2L,POLR2J,POLR2K,POLR2D,GTF2H2,POLR2A,GTF2F1 |
| 3.864e-02 | -3.25 | UBE2E3 (ubiquitin conjugating enzyme E2 E3) | protein interactions | 10477 | 103 | 24 | 17029 | 2761 |
USP7,RBX1,RNF25,NKD2,CUL3,CUL1,ATXN1,TOPORS,RANGAP1,BRCA1,WWP2,FBRS,RFWD3,DTL,MDM2,SIAH1,DDA1,TARDBP,TRIM32,KLHL42,RNF14,DDB1,RNF5,RNF114 |
| 3.864e-02 | -3.25 | PRKCB (protein kinase C beta) | protein interactions | 5579 | 103 | 24 | 17029 | 2761 |
DDX58,PDPK1,TRIM41,HABP4,SDC2,MKI67,RGS2,SHCBP1,LYN,EPB41,RB1,GNA12,PA2G4,HSPA4,GRK2,MAPK6,PTPN11,ARRB2,STAT3,PDLIM5,TERF1,DVL2,NUMB,SPTAN1 |
| 3.876e-02 | -3.25 | TMEM52B (transmembrane protein 52B) | protein interactions | 120939 | 34 | 10 | 17029 | 2761 |
ANKRD13D,PKP4,WDR44,PIK3R2,LRBA,RAB6A,SLC26A2,EHD4,RHEB,RHBDF2 |
| 3.876e-02 | -3.25 | RER1 (retention in endoplasmic reticulum sorting receptor 1) | protein interactions | 11079 | 34 | 10 | 17029 | 2761 |
UNK,IMMT,ERGIC3,VDAC2,TMEM216,SYVN1,ATP5F1A,RAB1A,BCAP31,TSPAN5 |
| 3.876e-02 | -3.25 | POP7 (POP7 homolog, ribonuclease P/MRP subunit) | protein interactions | 10248 | 34 | 10 | 17029 | 2761 |
POLA2,RPP25,VASP,POP7,KBTBD7,ENSA,COPS6,APP,RBM4,CCDC59 |
| 3.876e-02 | -3.25 | RMDN3 (regulator of microtubule dynamics 3) | protein interactions | 55177 | 34 | 10 | 17029 | 2761 |
RAF1,FAM3C,ILF3,GORASP2,YWHAZ,APOOL,TOMM40,HNRNPDL,PSEN1,MAPK1 |
| 3.876e-02 | -3.25 | PIK3CG (phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma) | protein interactions | 5294 | 34 | 10 | 17029 | 2761 |
ZNF282,NRAS,GRK2,IL6ST,PTPN11,PRMT7,KRAS,LYN,BECN1,HRAS |
| 3.876e-02 | -3.25 | EDEM1 (ER degradation enhancing alpha-mannosidase like protein 1) | protein interactions | 9695 | 34 | 10 | 17029 | 2761 |
DERL1,HLA-B,DNAJC10,SEC61B,PNISR,SEL1L,ESYT1,UBQLN2,PHF6,SSR1 |
| 3.876e-02 | -3.25 | NUMBL (NUMB like, endocytic adaptor protein) | protein interactions | 9253 | 34 | 10 | 17029 | 2761 |
SIAH1,TAB2,MAGED1,KBTBD7,ATXN1,GTSE1,RAB3IP,TRAF5,APP,SPSB3 |
| 3.876e-02 | -3.25 | LRRK1 (leucine rich repeat kinase 1) | protein interactions | 79705 | 34 | 10 | 17029 | 2761 |
CCT2,NAP1L1,SHC1,PTPN11,DAPK1,CUL3,FKBP5,DNAJA1,BRCA1,CDC37 |
| 3.876e-02 | -3.25 | NR2E1 (nuclear receptor subfamily 2 group E member 1) | protein interactions | 7101 | 34 | 10 | 17029 | 2761 |
DCAF6,DGCR8,HDAC7,IMPDH1,RCOR1,DDX5,ERBIN,SMURF1,HDAC2,TWISTNB |
| 3.876e-02 | -3.25 | MARF1 (meiosis regulator and mRNA stability factor 1) | protein interactions | 9665 | 34 | 10 | 17029 | 2761 |
CRKL,RB1,EIF4ENIF1,RBL1,ERF,DCP1A,GTSE1,FBXL19,FBRS,TERF2 |
| 3.881e-02 | -3.25 | positive regulation of apoptotic signaling pathway | biological process | GO:2001235 | 177 | 36 | 17256 | 2622 |
CYLD,TRAF7,NF1,DYNLL1,MAGED1,PLAGL2,BCL2L1,BCAP31,PARK7,APOPT1,MOAP1,PTPN2,TFAP4,SIAH1,PTEN,BCL2,TP53BP2,HTRA2,PPIF,BAK1,ATP5IF1,NCK1,MCL1,BCLAF1,PRKRA,FADD,DAPK3,FAS,TFDP1,PPP3R1,PML,E2F1,YWHAZ,TFDP2,YWHAH,FAF1 |
| 3.885e-02 | -3.25 | transcription corepressor activity | molecular function | GO:0003714 | 232 | 46 | 17224 | 2647 |
NCOR2,MECP2,ARID5A,SMARCA4,CTCF,PAWR,MXD4,DNAJB1,RCOR3,MXD1,SP100,KMT5A,MTA1,HDAC7,JAZF1,NOC2L,BRD7,CITED2,CCAR1,RLIM,RYBP,SAP30,ERF,EID1,CREG1,PBXIP1,DRAP1,ZMYND11,LDB1,RCOR1,CBFA2T2,TRIM28,PFDN5,GPS2,ZHX1,TONSL,HIPK2,NFIL3,SIAH2,RUVBL2,NR2F2,YY1,BEND6,TOB1,CBX4,N4BP2L2 |
| 3.885e-02 | -3.25 | GO_INCLUSION_BODY | MSigDB lists | GO_INCLUSION_BODY | 67 | 16 | 17377 | 2626 |
ATXN3,RAB11B,EID1,URB2,DNAJB2,CCZ1,ATXN1,PSEN1,PICALM,HSPA1B,PSMC4,RAD18,CCZ1B,CABIN1,NUP153,CLU |
| 3.887e-02 | -3.25 | buttock | COSMIC cancer mutations | buttock | 68 | 16 | 17385 | 2587 |
KIF5B,MTMR3,PWWP2A,RB1,NRAS,ZCCHC8,MTMR6,KRAS,NOTCH2,ERC1,HRAS,LMNA,MYO5A,CDKN2A,HLA-A,DCTN1 |
| 3.888e-02 | -3.25 | GO_FIBROBLAST_GROWTH_FACTOR_RECEPTOR_SIGNALING_PATHWAY | MSigDB lists | GO_FIBROBLAST_GROWTH_FACTOR_RECEPTOR_SIGNALING_PATHWAY | 83 | 19 | 17377 | 2626 |
SHOC2,RAB14,POLR2I,POLR2G,POLR2L,POLR2K,POLR2D,HNRNPF,TIA1,SHCBP1,POLR2A,MAPK3,GTF2F1,FGFR3,POLR2J,RPS27A,PTPN11,MAPK1,HNRNPM |
| 3.890e-02 | -3.25 | GO_ACTIVATION_OF_INNATE_IMMUNE_RESPONSE | MSigDB lists | GO_ACTIVATION_OF_INNATE_IMMUNE_RESPONSE | 201 | 40 | 17377 | 2626 |
DDX58,UBE2D3,CYLD,RAF1,CUL1,IRF3,PRKACA,PSMD9,LYN,BIRC2,PSMD2,PSMD1,CTSS,PSMA6,TANK,MAVS,CNPY3,PDPK1,NRAS,BIRC3,TNFAIP3,PSMA8,MAPKAPK3,PSMB7,PSMA1,UBE2V1,KRAS,ICAM2,PSMB9,PSMB3,FADD,PSMC4,RPS27A,TAB2,PSMD8,PSMD3,TICAM1,PSMC1,HRAS,IFI16 |
| 3.890e-02 | -3.25 | GO_RESPONSE_TO_INSULIN | MSigDB lists | GO_RESPONSE_TO_INSULIN | 201 | 40 | 17377 | 2626 |
MAX,WDTC1,ATP6V1B2,AP3S1,LYN,EEF2K,PTPN2,USF1,RAB8A,ATP6V0B,PDK2,SHC1,BDH1,PIK3R2,UPRT,ATP6V0A2,ATP6V0D1,MYO5A,ATP6V1G1,PDPK1,AKT2,DENND4C,PRKDC,ATP6V0A1,SRSF5,PDE3B,APPL1,SOCS7,CAT,TSC1,ATP6V1D,IDE,SCAP,OGT,ATP6V0C,ATP6V1C1,CDK2,ATP6V0E1,CPEB2,SLC25A33 |
| 3.891e-02 | -3.25 | regulatory region nucleic acid binding | molecular function | GO:0001067 | 878 | 154 | 17224 | 2647 |
RORB,IER2,MAX,H2AFZ,CXXC1,SNAPC4,MYEF2,PARK7,GLMP,CREM,USF1,GLIS2,ZNF639,ETV6,ZNF200,CRY2,SMARCE1,TIPARP,MYBL1,ARID4A,CCAR1,CARM1,CDC5L,SP3,DEAF1,KLF10,BAZ2A,GABPA,EAF2,BRCA1,SOX4,UBTF,HHEX,SMAD2,E2F4,PRDX5,ACTB,TFDP2,SMAD1,E2F2,HDAC2,ZNF564,HIVEP3,DHX9,CTCF,MEF2A,CDK13,THRAP3,TTF1,TFAP4,RB1,MLX,NFATC3,MED8,KLF16,MBD2,SSBP3,ZNF746,ZNF335,YBX1,TNRC18,ETV3,FOXK1,ZMYND11,MTA2,LDB1,MYBL2,ELK1,KDM3A,IRF5,ZNF174,RXRB,XRCC5,ETS2,RBMX,NFIL3,NLRC5,TBPL1,CEBPG,RUVBL2,YY1,RBBP4,TCF12,TRERF1,IVNS1ABP,FOXM1,SUZ12,SMARCA4,IRF3,RCOR3,MXD1,RRN3,NRF1,MTA1,GMEB1,ATF2,CDK12,CGGBP1,POU2AF1,KDM3B,KAT7,E2F3,WBP2,PCGF6,NFATC2,MEF2D,MBD3,TAF2,VEZF1,RBL1,SAFB,MAFK,STAT6,ARNTL,STAT1,ATF6,H3F3A,AKNA,SMAD4,CBX4,ATMIN,POU3F2,TCF3,AGO2,ARID5A,KLF13,NKRF,ETS1,FOXO3,IRF4,SUV39H2,PRDM4,BRD7,H2AFY,CARF,CREB1,STAT3,NCOA2,ZFP64,PSPC1,ZNF202,RCOR1,MEN1,KLF6,TFEB,TFE3,PITX1,TFDP1,E2F1,HMGB2,RBPJ,USF2,PURA,IFI16 |
| 3.892e-02 | -3.25 | haematopoietic_and_lymphoid_tissue-pharynx-haematopoietic_neoplasm-blastic_plasmacytoid_dendritic_cell_neoplasm | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-pharynx-haematopoietic_neoplasm-blastic_plasmacytoid_dendritic_cell_neoplasm | 47 | 12 | 17385 | 2587 |
GNAS,FGFR3,RB1,NRAS,PTEN,VHL,PTPN11,KRAS,STK11,HRAS,SMAD4,CDKN2A |
| 3.894e-02 | -3.25 | positive regulation of cell growth | biological process | GO:0030307 | 160 | 33 | 17256 | 2622 |
FGFR1OP,ADAM10,RPS6KA1,CIB1,CSNK2A1,HDGFL2,TWF2,RAB11A,CDC42,MEGF8,ZNF639,PIN1,ZFYVE27,BCL2,MTPN,CDKN2AIP,CYFIP1,RHOA,ADAM17,ANAPC2,EXOSC9,MACF1,EIF4G2,GOLGA4,PLAA,LIMK1,DNPH1,TRIM32,RUFY3,H3F3A,SMURF1,SLC25A33,ADNP2 |
| 3.894e-02 | -3.25 | cysteine-type endopeptidase activity | molecular function | GO:0004197 | 87 | 20 | 17224 | 2647 |
USP7,CASP6,USP10,PEF1,USP5,CFLAR,ATG4A,CAPN2,CTSL,PDCD6,CTSS,CAPN7,SRI,USP20,USP11,ESPL1,SENP1,CAPN1,USP34,USP13 |
| 3.897e-02 | -3.24 | GSE26351_WNT_VS_BMP_PATHWAY_STIM_HEMATOPOIETIC_PROGENITORS_DN | MSigDB lists | GSE26351_WNT_VS_BMP_PATHWAY_STIM_HEMATOPOIETIC_PROGENITORS_DN | 178 | 36 | 17377 | 2626 |
HIVEP3,GGNBP2,LUZP1,ALKBH5,MON1B,RRAGC,NKRF,XPNPEP3,XPO7,REPS1,UBLCP1,C14orf119,RNF121,CLUAP1,IL6ST,RAB35,UBA5,SOCS6,LUC7L2,ZDHHC18,TRIM8,MAPRE2,LAP3,PSMA8,MAP3K4,PPP2CA,ZNF862,ATP6V1D,PCM1,FAM3C,BAZ1B,TATDN1,ZSWIM3,MAP3K5,NMD3,SNX14 |
| 3.897e-02 | -3.24 | GSE36392_TYPE_2_MYELOID_VS_EOSINOPHIL_IL25_TREATED_LUNG_UP | MSigDB lists | GSE36392_TYPE_2_MYELOID_VS_EOSINOPHIL_IL25_TREATED_LUNG_UP | 178 | 36 | 17377 | 2626 |
HEXB,PMS2,DLGAP4,EBNA1BP2,THRAP3,RCOR3,EXT2,SRRT,RAD23A,FERMT3,PHC2,DTL,CTNNBL1,DPYSL2,RABGAP1L,IL6ST,TRMU,BCL2,MAST2,KCNAB2,TACC3,RBM15B,SGCE,CYFIP1,LAP3,LRBA,TOR1AIP2,CBFB,LSG1,TARS,SOCS7,MAGED2,DTWD1,PIEZO1,MYO9A,CD81 |
| 3.897e-02 | -3.24 | GO_DNA_PACKAGING | MSigDB lists | GO_DNA_PACKAGING | 178 | 36 | 17377 | 2626 |
ASH1L,HJURP,UBN1,SHPRH,CTCF,CCNB1,NCAPG,OIP5,AKAP8,NOC2L,H2AFY,CENPM,NAP1L4,TNRC18,HP1BP3,SMC4,NASP,TSPYL4,NUSAP1,SMC2,MCM2,ASF1B,CHAF1A,PAF1,NAP1L1,BRD2,CDCA5,H2AFX,CABIN1,HMGB2,CENPT,H3F3A,RBBP4,NAA60,IPO4,CDKN2A |
| 3.897e-02 | -3.24 | GSE17974_IL4_AND_ANTI_IL12_VS_UNTREATED_12H_ACT_CD4_TCELL_UP | MSigDB lists | GSE17974_IL4_AND_ANTI_IL12_VS_UNTREATED_12H_ACT_CD4_TCELL_UP | 178 | 36 | 17377 | 2626 |
POU3F2,UBL3,C9orf78,MTX3,C16orf87,DNAJB9,FASTKD3,NUDT19,TET3,VMP1,WDR44,UPRT,ATP6V0A2,NFU1,RNF19A,POC5,SMC4,PTPRK,CLCN3,PHF20L1,ERMP1,ZNF84,NET1,ZMYM5,CAMSAP1,SOX4,BUD13,TTC33,SLC50A1,MOSPD3,LEMD2,SMAD2,MAPK6,TFDP1,RRS1,NIPA1 |
| 3.897e-02 | -3.24 | GSE25123_WT_VS_PPARG_KO_MACROPHAGE_IL4_AND_ROSIGLITAZONE_STIM_DN | MSigDB lists | GSE25123_WT_VS_PPARG_KO_MACROPHAGE_IL4_AND_ROSIGLITAZONE_STIM_DN | 178 | 36 | 17377 | 2626 |
ZNF296,ZNF496,SUZ12,DLGAP4,ACAP1,UBQLN2,SLC20A1,KIAA1147,RAB21,FUT8,TTC3,TTC4,CTDSP2,FGFR1OP2,MICAL3,PAQR6,ORAI2,FOXK1,DENND1B,EMB,ATP2C1,MEF2D,PRMT2,EIF4G2,PLEKHF2,ZFR,RPSA,CBX3,DDX17,AKAP1,ANKRD10,OGT,USP20,SAMD8,SPCS3,TRAF5 |
| 3.910e-02 | -3.24 | response to lead ion | biological process | GO:0010288 | 22 | 7 | 17256 | 2622 |
CAT,PPP2CA,DNMT3A,PPP5C,BECN1,APP,CPOX |
| 3.910e-02 | -3.24 | hyperosmotic response | biological process | GO:0006972 | 22 | 7 | 17256 | 2622 |
AKR1B1,PDPK1,ARHGEF2,SLC12A2,RCSD1,SLC2A1,XRCC5 |
| 3.910e-02 | -3.24 | cellular response to misfolded protein | biological process | GO:0071218 | 22 | 7 | 17256 | 2622 |
DERL1,ANKZF1,SDF2L1,ATXN3,KLHL15,RNF5,CUL3 |
| 3.910e-02 | -3.24 | regulation of mRNA 3'-end processing | biological process | GO:0031440 | 22 | 7 | 17256 | 2622 |
PAF1,CTR9,CCNB1,AHCYL1,CDC73,SNRPA,PAPOLA |
| 3.910e-02 | -3.24 | negative regulation of DNA-dependent DNA replication | biological process | GO:2000104 | 22 | 7 | 17256 | 2622 |
TIMELESS,CHEK2,SMC3,ZNF830,BLM,TERF1,TERF2 |
| 3.910e-02 | -3.24 | positive regulation of posttranscriptional gene silencing | biological process | GO:0060148 | 22 | 7 | 17256 | 2622 |
TGFB1,DDX5,FXR1,STAT3,MAP2K2,AGO2,DHX9 |
| 3.910e-02 | -3.24 | nucleotide-excision repair, DNA duplex unwinding | biological process | GO:0000717 | 22 | 7 | 17256 | 2622 |
RBX1,GTF2H2,RPS27A,DDB1,XPA,RAD23B,CHD1L |
| 3.913e-02 | -3.24 | Azathioprine Action Pathway | SMPDB pathways | SMP00427 | 47 | 13 | 992 | 167 |
ADSS,GART,TXN,GUK1,GUCY1B1,ATIC,RAC1,RRM1,IMPDH1,ADSL,RRM2,SLC29A1,ABCC5 |
| 3.913e-02 | -3.24 | Mercaptopurine Action Pathway | SMPDB pathways | SMP00428 | 47 | 13 | 992 | 167 |
ADSS,GART,TXN,GUK1,ATIC,GUCY1B1,RAC1,RRM1,IMPDH1,ADSL,RRM2,SLC29A1,ABCC5 |
| 3.913e-02 | -3.24 | Thioguanine Action Pathway | SMPDB pathways | SMP00430 | 47 | 13 | 992 | 167 |
ADSS,GART,TXN,GUK1,GUCY1B1,ATIC,RAC1,RRM1,IMPDH1,ADSL,RRM2,SLC29A1,ABCC5 |
| 3.919e-02 | -3.24 | FHL2 (four and a half LIM domains 2) | protein interactions | 2274 | 145 | 32 | 17029 | 2761 |
CYLD,PHB2,FAM129A,CNOT11,ITGB5,APP,NRF1,USF1,MDM2,DCP1A,CREB1,STAT3,ZFP64,ADAM17,E2F3,ATXN1,CAPZA2,BRCA1,MCM2,ECH1,SMAD2,DSN1,CSK,E2F4,E2F1,ITGB1,MAPK1,E2F2,TOB1,SMAD4,IFI16,CAPN1 |
| 3.922e-02 | -3.24 | AB_hydrolase_1 | interpro domains | IPR000073 | 27 | 8 | 18492 | 2768 |
ABHD11,ABHD2,ABHD14B,EPHX2,ABHD14A,PPME1,ABHD5,ABHD16A |
| 3.922e-02 | -3.24 | Transl_B-barrel_sf | interpro domains | IPR009000 | 27 | 8 | 18492 | 2768 |
GSPT2,EFTUD2,TUFM,EFL1,GAR1,GUF1,MRPL3,GFM2 |
| 3.923e-02 | -3.24 | GTF2F1 (general transcription factor IIF subunit 1) | protein interactions | 2962 | 98 | 23 | 17029 | 2761 |
CCNC,CTDP1,POLR2G,CIRBP,POLR2D,CSNK2A1,JMJD6,KIF2C,BRCA1,RFC2,CDC73,PIP4K2A,SNRPA,POLR2A,DUS3L,POLR2J,KPNA2,PSAP,TCEA1,COIL,EEF1D,VPS29,SSSCA1 |
| 3.934e-02 | -3.24 | ovary-low_malignant_potential_(borderline)_tumour-serous | COSMIC cancer mutations | ovary-low_malignant_potential_(borderline)_tumour-serous | 32 | 9 | 17385 | 2587 |
FGFR3,RB1,PTEN,GOPC,KRAS,BRCA1,SMAD4,HRAS,CDKN2A |
| 3.935e-02 | -3.24 | USP_3 | prosite domains | PS50235 | 73 | 16 | 12060 | 1670 |
USP7,CYLD,USP42,USP39,USP10,USP22,USP48,USP21,USP36,USP5,USP32,USP20,USP11,USP53,USP34,USP13 |
| 3.939e-02 | -3.23 | GSE14415_INDUCED_TREG_VS_FOXP3_KO_INDUCED_TREG_UP | MSigDB lists | GSE14415_INDUCED_TREG_VS_FOXP3_KO_INDUCED_TREG_UP | 161 | 33 | 17377 | 2626 |
SLC12A7,ABCA3,KRBA1,WDR13,TOP2B,DOCK11,CRLF3,RAPGEF6,CD320,PA2G4,IL6ST,BDH1,TTC3,METTL9,PIKFYVE,N4BP2,TPCN1,RPL8,RPS10,RAB3IP,ARID1A,TANC1,ARHGAP15,STOML2,SH3BP5,PEX5,BRWD1,PRDX3,CHD3,GALNT10,RPS26,GPATCH4,PRPF4B |
| 3.944e-02 | -3.23 | CHIARADONNA_NEOPLASTIC_TRANSFORMATION_CDC25_DN | MSigDB lists | CHIARADONNA_NEOPLASTIC_TRANSFORMATION_CDC25_DN | 144 | 30 | 17377 | 2626 |
GALK1,IMMT,ACP2,RHOA,GUK1,CSRP1,AGRN,DAP,TRAK1,ASAH1,CSNK2A1,EMP3,SLC29A1,ADRB2,MAP1LC3B,WWP2,TRIM47,ATP6V0B,CLIC4,STAT6,MEA1,SRI,ARHGEF2,CYB5R1,TALDO1,TMEM159,TOB1,TMBIM1,ANXA11,ABCC1 |
| 3.947e-02 | -3.23 | CDP-diacylglycerol biosynthesis I | BIOCYC pathways | META_PWY-5667 | 5 | 3 | 902 | 157 |
AGPAT3,AGPAT2,AGPAT1 |
| 3.950e-02 | -3.23 | ITPA (inosine triphosphatase) | protein interactions | 3704 | 53 | 14 | 17029 | 2761 |
HNRNPA2B1,PDCD6,WDR1,TKT,NSFL1C,TOR1AIP2,GLO1,SSNA1,UBE2V1,PDXK,FKBP2,PPA1,PARK7,IMPA2 |
| 3.950e-02 | -3.23 | KANK2 (KN motif and ankyrin repeat domains 2) | protein interactions | 25959 | 53 | 14 | 17029 | 2761 |
GOLGA2,FOXK1,DYNLL1,TXLNA,DCP1A,CSNK2A1,CNTROB,NCOA1,MOB1A,PRMT2,SEC16A,PSEN1,NCOA2,SRPK2 |
| 3.950e-02 | -3.23 | ADNP (activity dependent neuroprotector homeobox) | protein interactions | 23394 | 53 | 14 | 17029 | 2761 |
ZNF524,KPNA1,CDC27,HDAC7,DYNLL1,SMARCA4,EBNA1BP2,NFATC2,ARID1A,RBPJ,RRS1,MAP1LC3B,POLG2,CBX3 |
| 3.950e-02 | -3.23 | AKAP8 (A-kinase anchoring protein 8) | protein interactions | 10270 | 53 | 14 | 17029 | 2761 |
RPA2,EWSR1,CUL3,CSNK2A1,CRY2,DDX5,BRCA1,RUVBL2,MCM2,MATR3,EEF1D,RPA1,CAND1,CDC5L |
| 3.950e-02 | -3.23 | NUMB (NUMB, endocytic adaptor protein) | protein interactions | 8650 | 53 | 14 | 17029 | 2761 |
MDM2,SIAH1,DPYSL2,TULP3,KBTBD7,LNX2,GTSE1,CAPZA2,CLTB,ANLN,ITGB5,IGBP1,APP,TERF2 |
| 3.950e-02 | -3.23 | CCNH (cyclin H) | protein interactions | 902 | 53 | 14 | 17029 | 2761 |
RPA2,CCNC,TRIM8,GOLGA2,MTA1,HNRNPF,PSMA1,BRCA1,CDK2,GTF2H2,POLR2A,SSSCA1,RPA1,FUBP1 |
| 3.950e-02 | -3.23 | ZMYND8 (zinc finger MYND-type containing 8) | protein interactions | 23613 | 53 | 14 | 17029 | 2761 |
USP7,DDX24,CHERP,PBXIP1,INTS1,MTA1,MTA2,MBD2,RBM8A,KCTD17,SMARCA4,KRAS,MBD3,HDAC2 |
| 3.950e-02 | -3.23 | TMPRSS11B (transmembrane serine protease 11B) | protein interactions | 132724 | 53 | 14 | 17029 | 2761 |
CD59,HLA-B,SLC31A1,SLC38A7,MIA2,B4GALT1,ST3GAL2,DHFR2,SCARB1,TMEM8A,EDEM2,VKORC1,HLA-A,PTPRK |
| 3.950e-02 | -3.23 | TNIK (TRAF2 and NCK interacting kinase) | protein interactions | 23043 | 53 | 14 | 17029 | 2761 |
DST,NCOR2,GOLGA4,NCK1,TAB2,HARS,DPYSL2,KBTBD7,CEP63,CLU,SMARCE1,MACF1,SMURF1,DPYSL3 |
| 3.950e-02 | -3.23 | NAPA (NSF attachment protein alpha) | protein interactions | 8775 | 53 | 14 | 17029 | 2761 |
RPA2,NAPG,GNA12,NSF,SNAP29,DHX29,SNAP23,TRMT6,KRAS,ATP6V1B2,STX16,GOSR1,APP,RPA1 |
| 3.953e-02 | -3.23 | ANK_REPEAT | prosite domains | PS50088 | 232 | 42 | 12060 | 1670 |
MIB2,ANKRD27,MPHOSPH8,PPP1R12A,YTHDC2,ANK3,ACAP1,NOTCH2,PPP1R16B,GIT2,ANKIB1,ANKRD23,ANKRD39,ANKRD28,ANKRD26,CDKN2C,ANKLE1,ASAP2,ZDHHC13,PPP1R12C,DAPK1,FEM1B,OSTF1,ANKRD13C,TP53BP2,ANKHD1,ASB6,ANKRD9,MTPN,ANKRD37,ANKRD33B,EHMT1,RFXANK,TANC1,ASB13,ANKRD46,KRIT1,ANKRD10,ANKZF1,TONSL,RNASEL,SLF1 |
| 3.955e-02 | -3.23 | BROWNE_HCMV_INFECTION_12HR_DN | MSigDB lists | BROWNE_HCMV_INFECTION_12HR_DN | 94 | 21 | 17377 | 2626 |
PRIM2,ACSL3,TRAK1,SDC2,ATXN1,NUP155,SNRPA,PAIP1,NMT2,SPAG5,HNRNPH3,RABGAP1L,U2SURP,RBMS1,SRSF3,ZMIZ1,MAP3K5,UBE2C,TSPAN5,TUBB,VPS13B |
| 3.961e-02 | -3.23 | AUF1 (hnRNP D0) binds and destabilizes mRNA | REACTOME pathways | R-HSA-450408 | 57 | 15 | 10287 | 1696 |
PSMD2,PSMD1,PSMA6,PSMA8,RPS27A,PSMD8,PSMD3,PSMB7,PSMA1,PSMB9,PSMD9,PSMC1,PABPC1,PSMB3,PSMC4 |
| 3.962e-02 | -3.23 | HMG_box_dom | interpro domains | IPR009071 | 52 | 13 | 18492 | 2768 |
UBTF,SP100,CIC,HMGXB3,BBX,WDHD1,HMGB2,PBRM1,KMT2C,SOX4,SMARCE1,HMG20A,SSRP1 |
| 3.963e-02 | -3.23 | INTEGRINB | prints domains | PR01186 | 8 | 3 | 4652 | 473 |
ITGB8,ITGB5,ITGB1 |
| 3.970e-02 | -3.23 | LABBE_WNT3A_TARGETS_UP | MSigDB lists | LABBE_WNT3A_TARGETS_UP | 105 | 23 | 17377 | 2626 |
TGFB1,GADD45G,MKI67,RRM2,RACGAP1,LY6E,SHCBP1,NMT2,PRIM1,GNAS,HHEX,CCNA2,ADD3,PCNA,DCK,SIVA1,AXIN2,LY75,KPNA2,ACTB,CCNB2,DNMT1,ADCY7 |
| 3.970e-02 | -3.23 | WANG_HCP_PROSTATE_CANCER | MSigDB lists | WANG_HCP_PROSTATE_CANCER | 105 | 23 | 17377 | 2626 |
SH2D3A,DNAJB2,UBXN1,GSPT2,B4GALT1,RGS2,FOXO3,TFEB,AHNAK,CRAT,GADD45B,PITX1,E2F1,SOCS6,CCDC69,AEN,CTSA,AFF1,PDXK,CITED2,PDLIM5,FUBP1,SPTAN1 |
| 3.970e-02 | -3.23 | BOYAULT_LIVER_CANCER_SUBCLASS_G1_UP | MSigDB lists | BOYAULT_LIVER_CANCER_SUBCLASS_G1_UP | 105 | 23 | 17377 | 2626 |
CCZ1,ABCC10,MAP4K4,RBM8A,CRNKL1,TIA1,RABIF,DNAJC9,PAIP1,LMNA,RPA1,NAP1L1,AHNAK,TTLL4,STT3A,RPL17,INPP5A,CCZ1B,TTC3,B4GALT3,PDCD4,PRPF4B,USP34 |
| 3.971e-02 | -3.23 | ESC/E(Z) complex | cellular component | GO:0035098 | 18 | 6 | 18223 | 2701 |
H2AFY,EZH1,RBBP4,EPOP,SUZ12,HDAC2 |
| 3.971e-02 | -3.23 | pore complex | cellular component | GO:0046930 | 18 | 6 | 18223 | 2701 |
PPIF,BAK1,BCL2,TOMM40,VDAC1,VDAC2 |
| 3.971e-02 | -3.23 | GSE15330_WT_VS_IKAROS_KO_MEGAKARYOCYTE_ERYTHROID_PROGENITOR_DN | MSigDB lists | GSE15330_WT_VS_IKAROS_KO_MEGAKARYOCYTE_ERYTHROID_PROGENITOR_DN | 184 | 37 | 17377 | 2626 |
IER2,PRKAB1,PARP12,DCAF15,XAB2,SLC41A1,WDR13,CDT1,UBE2Z,CHIC2,ETS1,CCDC28A,SEC11A,CSDE1,SHC1,INPP5A,CRAT,S100A6,PREB,RB1CC1,SELPLG,KIAA0930,WBP2,RCOR1,ICAM2,CBFA2T2,SERP1,SMAP2,RHOB,EPB41,WAS,UAP1,ACOX1,SIAH2,TBPL1,LONP2,RNF114 |
| 3.971e-02 | -3.23 | GSE39820_TGFBETA3_IL6_VS_TGFBETA3_IL6_IL23A_TREATED_CD4_TCELL_DN | MSigDB lists | GSE39820_TGFBETA3_IL6_VS_TGFBETA3_IL6_IL23A_TREATED_CD4_TCELL_DN | 184 | 37 | 17377 | 2626 |
ZNF76,LYRM4,MRPL42,TMBIM4,RPLP2,UQCR10,COPE,SLC25A12,SDF2L1,IFT27,MRPL19,PNO1,CD320,SAP130,FBXO7,MRPL34,RPF2,OSTF1,SPTSSA,CITED2,ZNRD1,MRPL32,ABCC5,PPAN,TMEM39A,MRPL16,MRPS14,STOML2,MBIP,WAS,PPP2R5A,MAFK,LRPPRC,TICAM1,OSGEPL1,EYA2,HDAC2 |
| 3.971e-02 | -3.23 | GSE15659_CD45RA_NEG_CD4_TCELL_VS_ACTIVATED_TREG_DN | MSigDB lists | GSE15659_CD45RA_NEG_CD4_TCELL_VS_ACTIVATED_TREG_DN | 184 | 37 | 17377 | 2626 |
SEPHS2,UBL3,ZCCHC9,TRIP12,ZNF316,SF3B1,SLC41A1,TOR1AIP1,TMEM97,RRM1,SLC4A2,S1PR2,RPAIN,WRB,POP7,ZNF200,ZNRD1,USP34,PSRC1,TSTA3,TOP3A,SSR2,PLEKHM3,STX16,RAB2B,SMAP2,PPP2CA,PPP2R5A,PRDX3,TIMM17A,VCPIP1,ROCK1,USP11,WDR91,SMAD1,YY1,ZNF720 |
| 3.971e-02 | -3.23 | GSE46606_UNSTIM_VS_CD40L_IL2_IL5_1DAY_STIMULATED_IRF4_KO_BCELL_UP | MSigDB lists | GSE46606_UNSTIM_VS_CD40L_IL2_IL5_1DAY_STIMULATED_IRF4_KO_BCELL_UP | 184 | 37 | 17377 | 2626 |
SRM,UBE2E2,TP53RK,GSPT2,TMEM109,MEF2A,SLC20A1,KRR1,FERMT3,FKBP1A,PA2G4,HOMER1,PRKD3,NSFL1C,FNIP2,TTLL12,DNMT1,RPL22L1,TRIM14,TERF2,PRPF19,ADCY7,ATP13A1,MAPKAPK3,DENND4C,MFNG,MFN2,ATP1A1,FBXO41,CCDC86,CCDC14,ZNF330,PTER,STAT1,NCLN,IFI16,SSRP1 |
| 3.976e-02 | -3.22 | central_nervous_system-third_ventricle-glioma-astrocytoma_Grade_I | COSMIC cancer mutations | central_nervous_system-third_ventricle-glioma-astrocytoma_Grade_I | 37 | 10 | 17385 | 2587 |
GNAS,FGFR3,NRAS,PTEN,PTPN11,CLCN6,KRAS,HRAS,MAP2K2,CDKN2A |
| 3.976e-02 | -3.22 | ovary-low_malignant_potential_(borderline)_tumour-mucinous | COSMIC cancer mutations | ovary-low_malignant_potential_(borderline)_tumour-mucinous | 37 | 10 | 17385 | 2587 |
GNAS,FGFR3,NRAS,PTEN,SF3B1,KRAS,BRCA1,ARID1A,SMAD4,CDKN2A |
| 3.977e-02 | -3.22 | RAB11A (RAB11A, member RAS oncogene family) | protein interactions | 8766 | 93 | 22 | 17029 | 2761 |
RAB11B,PHB2,UQCR10,RAB7A,ILF3,CYSTM1,MYH9,NUTF2,ARF1,RAB1A,PSEN1,RAB5B,RAB11A,OPTN,SH3BP5,MTMR4,WDR44,ATF2,PGAM1,RAB3IL1,MYO5A,CARM1 |
| 3.977e-02 | -3.22 | GIT2 (GIT ArfGAP 2) | protein interactions | 9815 | 93 | 22 | 17029 | 2761 |
CCDC93,MAX,RPRD1A,TNFAIP3,RCOR1,NUF2,SAFB2,PSMD9,RUFY1,GIT2,HMG20A,OIP5,FBXO28,GRK2,GRIPAP1,RABGAP1L,ARNTL,SH3GLB2,CORO1A,POLR1B,MVP,E2F2 |
| 3.981e-02 | -3.22 | Cytosine methylation | WikiPathways | WP3585 | 9 | 4 | 5312 | 837 |
TET3,MBD3,MECP2,DNMT1 |
| 3.981e-02 | -3.22 | Mismatch repair | WikiPathways | WP531 | 9 | 4 | 5312 | 837 |
PCNA,MSH6,RPA1,MSH2 |
| 3.987e-02 | -3.22 | nucleobase-containing small molecule biosynthetic process | biological process | GO:0034404 | 149 | 31 | 17256 | 2622 |
ADA2,GALK1,TK1,GUK1,NUDT4,AMD1,UCK2,LDHA,UCK1,OGDH,ADPGK,PKM,PDE3B,NEIL2,MBD4,HINT1,DUT,DCK,CTPS1,UPRT,IMPDH1,DHTKD1,DNPH1,GPI,DHFR2,PGAM1,NUDT11,OGG1,PDCL3,PFKP,NUDT3 |
| 3.995e-02 | -3.22 | REACTOME_METABOLISM_OF_LIPIDS_AND_LIPOPROTEINS | MSigDB lists | REACTOME_METABOLISM_OF_LIPIDS_AND_LIPOPROTEINS | 463 | 84 | 17377 | 2626 |
CCNC,HEXB,AGPAT1,CHKB,CDIPT,PRKACA,GGPS1,LCLAT1,DECR1,NRF1,MTMR4,PIK3R2,LPIN2,SLC44A1,HADHB,AKR1B1,TECR,GPD1L,GM2A,ACSL5,MTMR6,SUMF2,PITPNB,TAZ,ABHD5,AGPAT2,CERS6,ARNTL,MBOAT1,SCARB1,NCOA1,CHPT1,ABCA1,NCOR2,CDS2,MUT,CERK,MED13L,ASAH1,AGPAT3,SUMF1,ARF1,PMVK,PIP4K2A,PIP5K1C,EBP,CHKA,MED10,MED8,PTEN,CRAT,BDH1,ABCD1,PCYT2,PIKFYVE,LPCAT1,NCOA2,MED22,SLC25A1,FDFT1,CSNK1G2,ELOVL5,GALC,PGS1,NSDHL,ACSL3,GBA,PNPLA8,ARSK,NEU1,RDH11,PI4K2A,MTMR3,PLD3,ACOX1,LPCAT4,ACLY,ACAT1,CTSA,ACADM,PSAP,SMPD4,HEXA,PTDSS1 |
| 3.998e-02 | -3.22 | Cyclin_N | pfam domains | PF00134 | 32 | 9 | 17054 | 2545 |
CCNC,CCNK,CCNA2,CCNL2,CABLES2,CCNB1,CCNF,CCNB2,CABLES1 |
| 3.998e-02 | -3.22 | WAMUNYOKOLI_OVARIAN_CANCER_LMP_UP | MSigDB lists | WAMUNYOKOLI_OVARIAN_CANCER_LMP_UP | 248 | 48 | 17377 | 2626 |
NADSYN1,SART1,TXN,NQO1,NDUFAF2,DNAJB2,RPS6KA1,TRAK1,CIB1,TM9SF3,SMARCA4,NANS,BZW2,EBP,CD59,GSTK1,C1GALT1,POP7,RRBP1,FNIP2,TALDO1,MVP,TTLL12,ZNRD1,ANKRD9,IMPA2,S100A6,FDFT1,TSTA3,NET1,AACS,JTB,ABHD11,EDF1,GALNT7,TOMM40,PWWP2B,INF2,GOLGA2,DBI,DHTKD1,ARRDC1,CANT1,ACTB,SLC22A23,CHPT1,MYL12B,ZNF564 |
| 4.000e-02 | -3.22 | GO_TRANSCRIPTION_COREPRESSOR_ACTIVITY | MSigDB lists | GO_TRANSCRIPTION_COREPRESSOR_ACTIVITY | 213 | 42 | 17377 | 2626 |
NCOR2,MECP2,CTCF,SMARCA4,PAWR,MXD4,RCOR3,MXD1,SP100,HDAC7,MTA1,JAZF1,NOC2L,BRD7,CITED2,CCAR1,RLIM,SAP30,RYBP,PBXIP1,EID1,ERF,CREG1,DRAP1,ZMYND11,LDB1,RCOR1,CBFA2T2,TRIM28,PFDN5,TONSL,GPS2,ZHX1,HIPK2,NFIL3,SIAH2,YY1,NR2F2,BEND6,TOB1,CBX4,N4BP2L2 |
| 4.002e-02 | -3.22 | adrenal_gland-adrenal_gland-adrenal_cortical_adenoma-aldosterone_producing | COSMIC cancer mutations | adrenal_gland-adrenal_gland-adrenal_cortical_adenoma-aldosterone_producing | 90 | 20 | 17385 | 2587 |
SAMD4B,DNMT3A,NRAS,LONRF3,KRAS,SYVN1,PPWD1,MYO9B,MEN1,GNAS,DLG5,ATP1A1,OSBPL8,MED15,TYW5,PTPN11,YY1,PITRM1,HRAS,ABCC5 |
| 4.014e-02 | -3.22 | KYNG_DNA_DAMAGE_BY_UV | MSigDB lists | KYNG_DNA_DAMAGE_BY_UV | 62 | 15 | 17377 | 2626 |
SNX8,VASP,PDCD10,PTPN18,THOC1,GALC,INPP5A,UBR2,KIF14,RAB7A,CAB39,TFDP2,PRKACA,STAT3,GM2A |
| 4.014e-02 | -3.22 | DACOSTA_UV_RESPONSE_VIA_ERCC3_TTD_UP | MSigDB lists | DACOSTA_UV_RESPONSE_VIA_ERCC3_TTD_UP | 62 | 15 | 17377 | 2626 |
BAK1,PPIF,GALK1,PLD3,GALNT2,ADD1,PDAP1,ADO,TMX4,STAT1,MYBL2,ASNA1,FKBP2,STX16,CBX4 |
| 4.014e-02 | -3.22 | SHEDDEN_LUNG_CANCER_GOOD_SURVIVAL_A5 | MSigDB lists | SHEDDEN_LUNG_CANCER_GOOD_SURVIVAL_A5 | 62 | 15 | 17377 | 2626 |
PDK2,PKP4,CHERP,DCAF15,XAB2,DNAJB2,SMARCA4,SLC29A1,DNAJB1,OTUD3,GGA2,RUFY3,ZNF518A,ARID4A,FBRS |
| 4.014e-02 | -3.22 | MODY_HIPPOCAMPUS_POSTNATAL | MSigDB lists | MODY_HIPPOCAMPUS_POSTNATAL | 62 | 15 | 17377 | 2626 |
PPP3CA,ATP2A2,COX8A,ATP6V0C,MDH1,GPI,ATP6V1C1,ATP6V1B2,VDAC1,CLTB,SDHA,HRAS,RHOB,MAPK3,LDHB |
| 4.015e-02 | -3.22 | Aminoacyl-tRNA biosynthesis | KEGG pathways | hsa00970 | 44 | 12 | 7161 | 1149 |
FARSA,LARS,KARS,EPRS,IARS,GATC,HARS,QARS,IARS2,QRSL1,TARS,CARS2 |
| 4.015e-02 | -3.22 | Aminoacyl-tRNA biosynthesis | KEGG pathways | ko00970 | 44 | 12 | 7161 | 1149 |
FARSA,KARS,EPRS,LARS,GATC,IARS,HARS,QARS,IARS2,QRSL1,TARS,CARS2 |
| 4.026e-02 | -3.21 | MODULE_212 | MSigDB lists | MODULE_212 | 319 | 60 | 17377 | 2626 |
NQO1,UGP2,RPLP2,SUCLG1,PHB2,HEXB,FLOT1,KIF23,CSNK2A1,GLUD1,OAT,EPHX2,CD320,EBP,CDK5,DECR1,PDK2,PCNA,CTSS,GART,GOT2,PIN1,DAPK1,PCYT2,MRPL40,TALDO1,SPTSSA,ALDH9A1,ABCC1,PLK1,FTL,RHOBTB3,LAP3,NQO2,ACSL3,LACTB,LDHA,RRM2,PFKFB3,GLO1,CADM1,MCFD2,HAGH,CYB5A,PRDX1,DPYSL3,HINT1,MAGT1,TMED10,DUSP3,PTPN7,RPLP1,ADAM9,MDH1,CNOT6,FKBP5,ACADM,CHPT1,HDAC2,DDX42 |
| 4.027e-02 | -3.21 | EEF1AKMT3 (EEF1A lysine methyltransferase 3) | protein interactions | 25895 | 58 | 15 | 17029 | 2761 |
CCT2,PFDN5,NTPCR,SMC3,SAR1A,PFDN4,HUWE1,MDH2,PPP6C,LDHA,DNAJA1,RUVBL2,IGBP1,CCT8,LDHB |
| 4.027e-02 | -3.21 | KIF22 (kinesin family member 22) | protein interactions | 3835 | 58 | 15 | 17029 | 2761 |
IMMT,KPNA4,PSRC1,FOXM1,SIAH1,STAT6,COX5A,ATXN1,BRCA1,FUS,CCNL2,TAF12,CCNB1,MAPK14,UTP4 |
| 4.027e-02 | -3.21 | PSME2 (proteasome activator subunit 2) | protein interactions | 5721 | 58 | 15 | 17029 | 2761 |
PSMD2,PSMD1,PSMA6,FBXO7,PSMB7,PSMA1,MCM2,RNF26,PSMB9,PSMC1,SPPL2B,APP,PSMB3,PARD3,PSMC4 |
| 4.027e-02 | -3.21 | POLA2 (DNA polymerase alpha 2, accessory subunit) | protein interactions | 23649 | 58 | 15 | 17029 | 2761 |
FGFR3,RBM23,PRIM2,DDX24,ARPC5,HELB,RAE1,SCYL1,POP7,RAC1,TKT,KLF6,APP,CAPN1,PRIM1 |
| 4.027e-02 | -3.21 | FANCG (Fanconi anemia complementation group G) | protein interactions | 2189 | 58 | 15 | 17029 | 2761 |
FANCL,ERCC1,PRDX3,FAAP100,PRKAA1,TOP3A,KIF15,XRCC3,RBPJ,BLM,FANCE,FTSJ3,CAPN1,RPA1,SPTAN1 |
| 4.027e-02 | -3.21 | EXOSC6 (exosome component 6) | protein interactions | 118460 | 58 | 15 | 17029 | 2761 |
MIF4GD,MDM2,EXOSC6,EXOSC7,PSMA6,EXOSC1,TUFM,CUL3,PSMA1,LSM8,EXOSC9,UPF2,SRSF3,DNAJC30,IFI16 |
| 4.027e-02 | -3.21 | PRMT2 (protein arginine methyltransferase 2) | protein interactions | 3275 | 58 | 15 | 17029 | 2761 |
RB1,PSRC1,KRBA1,ERF,PRRC2A,L3MBTL3,CXXC1,PIK3R2,TIGD5,E2F1,VCPIP1,NCOA1,CHEK2,PRMT2,PSMB3 |
| 4.027e-02 | -3.21 | CYCS (cytochrome c, somatic) | protein interactions | 54205 | 58 | 15 | 17029 | 2761 |
CAT,GSTK1,COQ10B,SAFB,VDAC2,ACAT1,BCL2,CYC1,BCL2L1,CYB5R1,VDAC1,CDK2,GPD1L,IMPA2,CYB5A |
| 4.027e-02 | -3.21 | PAF1 (PAF1 homolog, Paf1/RNA polymerase II complex component) | protein interactions | 54623 | 58 | 15 | 17029 | 2761 |
DNMT3A,POLR2G,PTPN11,CSNK2A1,CTR9,RTF1,TCEA1,CDC73,CHD1,IFI16,POLR2A,CHAF1A,SSRP1,XRCC5,SUPT16H |
| 4.029e-02 | -3.21 | integral component of organelle membrane | cellular component | GO:0031301 | 176 | 35 | 18223 | 2701 |
TOMM20,IMMT,SYS1,SLC39A13,PCSK7,ABCB10,PXMP2,SLC35B1,SLC35B2,SLC25A44,QSOX2,ANKLE1,TIMM23,SLC35B4,TPST1,YIF1B,ABCD1,APOOL,BAK1,VOPP1,COA3,MFNG,TOMM40,RHOT1,RHOT2,CHCHD6,TMEM201,MPC1,LEMD2,CHCHD3,YIF1A,GALNT2,TIMM17A,SLC25A19,SAMD8 |
| 4.029e-02 | -3.21 | GSE7568_IL4_TGFB_DEXAMETHASONE_VS_IL4_TGFB_TREATED_MACROPHAGE_DN | MSigDB lists | GSE7568_IL4_TGFB_DEXAMETHASONE_VS_IL4_TGFB_TREATED_MACROPHAGE_DN | 167 | 34 | 17377 | 2626 |
COMMD10,UBR2,SRGN,MED13L,SIKE1,MXD4,LYN,RNF103,CFLAR,GOLM1,SUB1,NFATC3,RABGAP1L,SLC35B4,MOB1A,F2R,HP1BP3,ERMP1,TNFAIP3,POLK,ZMYND11,EMB,ZMYM5,KRIT1,PFDN5,BRWD1,VPS26B,BBX,WDR7,FBXL3,EYA2,SNX14,CAPN1,ZSWIM6 |
| 4.029e-02 | -3.21 | GSE40225_WT_VS_RIP_B7X_DIABETIC_MOUSE_PANCREATIC_CD8_TCELL_UP | MSigDB lists | GSE40225_WT_VS_RIP_B7X_DIABETIC_MOUSE_PANCREATIC_CD8_TCELL_UP | 167 | 34 | 17377 | 2626 |
SNX27,ZBTB10,UBE2E2,PARP12,SHPRH,TSC22D3,SLC2A1,SMC6,PCSK7,DOCK11,ETS1,ABL2,APLP2,RB1,THADA,KLF16,ZNRF2,ZFYVE27,OSTF1,ABCC5,LARS,DEAF1,DENND4C,TLK1,GALNT7,KDM1B,MACF1,PLEKHF2,VEZF1,MID1IP1,TTC13,DTX4,CHPT1,ZC3HAV1 |
| 4.029e-02 | -3.21 | GSE14699_NAIVE_VS_ACT_CD8_TCELL_DN | MSigDB lists | GSE14699_NAIVE_VS_ACT_CD8_TCELL_DN | 167 | 34 | 17377 | 2626 |
SLC12A7,FAM208B,CYLD,CREBL2,LCLAT1,RAPGEF6,SLC25A36,CD3EAP,HDAC7,IL6ST,TTC3,FYTTD1,ELOVL5,DCAF6,TIMP2,FOXK1,PCGF6,ITM2A,RAB3IP,LRRC1,GAR1,MTR,SH3BP5,HSPB11,ETS2,ACYP1,HIPK2,FAM3C,APPL2,TCOF1,ABCA1,USP53,GPATCH4,NUMB |
| 4.033e-02 | -3.21 | GO_REGULATION_OF_INTRINSIC_APOPTOTIC_SIGNALING_PATHWAY | MSigDB lists | GO_REGULATION_OF_INTRINSIC_APOPTOTIC_SIGNALING_PATHWAY | 133 | 28 | 17377 | 2626 |
MIF,PGAP2,BCL2L12,PPIF,HSPH1,CYLD,NCK1,IVNS1ABP,VDAC2,PLAGL2,MCL1,BCLAF1,BCL2L1,SYVN1,PRKRA,PTTG1IP,BCAP31,PARK7,PTPN2,RRN3,SIAH1,NOC2L,ARHGEF2,PARL,BCL2,TRIM32,CLU,HTRA2 |
| 4.033e-02 | -3.21 | GSE12003_MIR223_KO_VS_WT_BM_PROGENITOR_8D_CULTURE_DN | MSigDB lists | GSE12003_MIR223_KO_VS_WT_BM_PROGENITOR_8D_CULTURE_DN | 133 | 28 | 17377 | 2626 |
GCC2,NPHP4,POC1A,CDCA3,GBA,KIF23,UBE2V1,RIT1,ASXL2,FOXO3,ANKRD26,PLD3,TSC1,WAS,PEX5,DBI,ITGB1,ARAP1,ATP6V0A2,CDKN1B,MBOAT1,CORO1A,MAP3K5,TMEM159,CCDC125,NAA60,ANXA11,TRIM14 |
| 4.039e-02 | -3.21 | salivary_gland-carcinoma-ex-pleomorphic_adenoma_carcinoma | COSMIC cancer mutations | salivary_gland-carcinoma-ex-pleomorphic_adenoma_carcinoma | 18 | 6 | 17385 | 2587 |
KRAS,STK11,NRAS,PTEN,HRAS,SMAD4 |
| 4.039e-02 | -3.21 | ex-pleomorphic_adenoma_carcinoma | COSMIC cancer mutations | ex-pleomorphic_adenoma_carcinoma | 18 | 6 | 17385 | 2587 |
KRAS,STK11,NRAS,PTEN,HRAS,SMAD4 |
| 4.039e-02 | -3.21 | haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-marginal_zone_lymphoma | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-marginal_zone_lymphoma | 18 | 6 | 17385 | 2587 |
CDKN2C,NOTCH2,BIRC3,TNFAIP3,STAT3,CDKN2A |
| 4.039e-02 | -3.21 | endometrium-carcinoma-clear_cell_carcinoma | COSMIC cancer mutations | endometrium-carcinoma-clear_cell_carcinoma | 18 | 6 | 17385 | 2587 |
KRAS,ARID1A,NRAS,PTEN,HRAS,CDKN2A |
| 4.039e-02 | -3.21 | haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-anaplastic_large_cell_lymphoma | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-lymphoid_neoplasm-anaplastic_large_cell_lymphoma | 18 | 6 | 17385 | 2587 |
KRAS,NRAS,TFG,STAT3,ATIC,CDKN2A |
| 4.041e-02 | -3.21 | GSE360_CTRL_VS_T_GONDII_MAC_DN | MSigDB lists | GSE360_CTRL_VS_T_GONDII_MAC_DN | 190 | 38 | 17377 | 2626 |
TMEM41B,SRGN,SLC2A1,SDC2,LETMD1,CDK13,BCL2L1,CDIPT,CRLF3,RBM4,PNO1,FLAD1,KDM2A,MSH2,CYC1,TP53BP2,UBE3C,FAM171A1,PCBP2,SP3,ELL2,HARS,ERLIN1,EZR,SLBP,PRPF3,PPFIA3,ODC1,MBD3,H2AFV,ALG3,HGS,CERS6,PFDN4,HNRNPR,TICAM1,DVL1,TRAF5 |
| 4.041e-02 | -3.21 | GSE11961_PLASMA_CELL_DAY7_VS_MEMORY_BCELL_DAY40_UP | MSigDB lists | GSE11961_PLASMA_CELL_DAY7_VS_MEMORY_BCELL_DAY40_UP | 190 | 38 | 17377 | 2626 |
CYTIP,MAX,MUT,PHF23,HLA-E,EYA1,TOP2B,EBNA1BP2,ATP6V1B2,STMN1,GTF2F1,EXOSC7,AKAP8,TPST1,PARL,POLR1B,GLE1,CITED2,GNAI2,TMX1,SRSF10,PDPK1,FAM49B,GABPA,CREG1,VDAC2,EIF2A,PRIM1,EIF3K,FNTA,HSPB11,RBL1,OAZ2,MDH1,ATP6V1C1,SMNDC1,RAB3IL1,SMARCD1 |
| 4.041e-02 | -3.21 | GSE22196_HEALTHY_VS_OBESE_MOUSE_SKIN_GAMMADELTA_TCELL_DN | MSigDB lists | GSE22196_HEALTHY_VS_OBESE_MOUSE_SKIN_GAMMADELTA_TCELL_DN | 190 | 38 | 17377 | 2626 |
RHOG,NCOR2,NQO1,TMEM41B,MEF2A,SLC4A2,ITGB5,BCAP31,LMNA,EBP,CAPN2,PSMD1,RAB35,RPN2,TIPARP,EEF1D,CDC37,PPIF,ORAI2,TNFAIP3,CSRP1,ZMYND11,EZR,EMP3,PLEC,DPYSL3,PI4K2A,EIF3K,SH3BP5,TPD52L2,UAP1,BRD2,TULP3,YWHAZ,ASNA1,PDXK,PLOD3,YWHAH |
| 4.041e-02 | -3.21 | GSE40274_FOXP3_VS_FOXP3_AND_PBX1_TRANSDUCED_ACTIVATED_CD4_TCELL_DN | MSigDB lists | GSE40274_FOXP3_VS_FOXP3_AND_PBX1_TRANSDUCED_ACTIVATED_CD4_TCELL_DN | 190 | 38 | 17377 | 2626 |
PKP4,DNMT3A,ARID5A,MCCC1,HMGN3,BIRC2,PIP4K2A,FANCI,MAN1A1,HOMER1,SLC44A1,DAPK1,TTC3,ALDH18A1,SLC12A2,NSUN4,ABCC1,UBQLN4,CELSR2,ZBED5,MAP4K3,RAB3IP,SOX4,PRMT2,CHCHD6,ANKRD46,SH3BP5,PTPRF,GNA12,INF2,PEX5,ETS2,ACADM,WIPI2,SMAD1,CHPT1,ABCA1,TMEM131 |
| 4.041e-02 | -3.21 | GSE42724_MEMORY_BCELL_VS_PLASMABLAST_UP | MSigDB lists | GSE42724_MEMORY_BCELL_VS_PLASMABLAST_UP | 190 | 38 | 17377 | 2626 |
ZBTB10,TM9SF4,PPP1R15B,TRAK1,CREBL2,AGFG1,KTN1,CFLAR,PRNP,RAB21,PDCD10,CLIC4,SIAH1,PRDM4,TAP2,TAGLN2,PPP6R1,NUP85,SLC25A1,MND1,CYTH1,ETV3,KIAA0040,SELPLG,COQ10B,PEF1,PATL1,ARF4,C1orf122,EPB41,CLK3,MAPK6,STAT1,PML,ACADM,FBXL3,CLN3,LRP8 |
| 4.049e-02 | -3.21 | NGF signalling via TRKA from the plasma membrane | REACTOME pathways | R-HSA-187037 | 387 | 77 | 10287 | 1696 |
TSC2,NF1,RPS6KA1,RAF1,PRKACA,MAPK14,CRKL,CALM2,VAV1,RAP1A,MDM2,PSMD1,PSMA6,SHC1,RALB,PIK3R2,ADCY9,DNM2,AP2B1,CDKN1B,AHCYL1,DNAL4,MLST8,ADCY7,NRAS,PSMA8,RBX1,AKT2,CUL3,PSMB7,PSMB9,PPP2CA,PPP2R5A,JAK1,RPS27A,PSMD8,PSMD3,PPP5C,ARRB2,MAPK1,PSMC1,AP2S1,AGO2,LAMTOR3,BRAP,MEF2A,AKT1S1,PSMD9,FOXO3,PIP4K2A,PIP5K1C,PSMD2,FGFR3,GRK2,PTEN,PTPN11,CREB1,STAT3,CAMK2G,SPTAN1,PDPK1,RHOA,MAPKAPK3,PRKAR1B,PIP4K2C,PSMA1,KRAS,RIT1,ELK1,MAP2K2,PSMB3,MAPK3,PSMC4,DUSP3,CSK,KBTBD7,HRAS |
| 4.050e-02 | -3.21 | CTGAGCC,MIR-24 | MSigDB lists | CTGAGCC,MIR-24 | 219 | 43 | 17377 | 2626 |
OTUD5,PHF23,WDTC1,DLGAP4,CREBL2,IP6K2,SNN,TMEM161B,ZER1,SAP130,VAV1,FGFR3,RAP1A,ADCY9,CLCN6,CDKN1B,ATP6V0A2,PLCL2,FBXL19,TMEM9,LYPLA2,PLK3,PHF20L1,MLEC,TAOK1,MEN1,RAB5B,MATR3,SFXN5,PTPRF,CACNB1,CSK,TAB2,PPM1G,DCAF11,OGT,H2AFX,ACBD4,CNOT6,CENPT,PSAP,MBD6,PURA |
| 4.056e-02 | -3.21 | GO_STEROID_HORMONE_RECEPTOR_BINDING | MSigDB lists | GO_STEROID_HORMONE_RECEPTOR_BINDING | 78 | 18 | 17377 | 2626 |
PHB2,SMARCA4,BRCA1,PRMT2,KDM3A,PARK7,DDX17,RB1,PCNA,ETS2,PIAS2,DDX5,NCOA1,RNF14,STAT3,YWHAH,DNMT1,NCOA2 |
| 4.060e-02 | -3.20 | RAP1GDS1 (Rap1 GTPase-GDP dissociation stimulator 1) | protein interactions | 5910 | 83 | 20 | 17029 | 2761 |
RHOA,NRAS,PPP1R2,RBM42,RHOC,RAC1,OLA1,KRAS,ABHD14A,UBTF,MBIP,RAP1A,CDC42,HDAC7,KIFAP3,PPP5C,TATDN1,CDK2,HRAS,CAPN1 |
| 4.060e-02 | -3.20 | RGS20 (regulator of G protein signaling 20) | protein interactions | 8601 | 83 | 20 | 17029 | 2761 |
PLK1,CTU2,KIF3B,PRIM2,MIOS,TYW1,NARF,ATP6V0A1,NLN,BOLA1,ADRB2,PMVK,GLRX3,GFER,ZNF696,NSF,TXLNA,FAM126A,RUVBL2,GNAI2 |
| 4.060e-02 | -3.20 | NCOA6 (nuclear receptor coactivator 6) | protein interactions | 23054 | 83 | 20 | 17029 | 2761 |
RORB,NCOR2,EWSR1,PRKDC,RANGAP1,KMT2C,PRMT2,WDR5,PAGR1,XRCC5,RB1,SMAD2,MED15,ZNF335,E2F1,KMT2B,FUS,NCOA1,ATF2,NCOA2 |
| 4.068e-02 | -3.20 | Cyclin_N | interpro domains | IPR006671 | 32 | 9 | 18492 | 2768 |
CCNC,CCNK,CCNA2,CCNL2,CABLES2,CCNB1,CCNF,CCNB2,CABLES1 |
| 4.068e-02 | -3.20 | regulation of histone modification | biological process | GO:0031056 | 138 | 29 | 17256 | 2622 |
TGFB1,ZFP64,KAT2A,TRIP12,KMT2E,EID1,KAT7,MECP2,WBP2,RTF1,BRCA1,CCNB1,KDM3A,MAPK3,IWS1,PAF1,PARG,AKAP8,NOC2L,ZNF335,OGT,KMT2B,H2AFY,CTR9,BRD7,RUVBL2,CHTOP,DNMT1,SMAD4 |
| 4.072e-02 | -3.20 | Insulin Signaling | WikiPathways | WP481 | 161 | 34 | 5312 | 837 |
TSC2,RAF1,RPS6KA1,RAC1,SLC2A1,PRKAA1,FLOT1,ARF1,GYG1,MAPK14,FOXO3,KIF5B,SHC1,PTEN,RAB4A,PIK3R2,PTPN11,MAP3K14,PDPK1,AKT2,MAP4K4,MAP4K3,ELK1,MAP2K2,RHEB,MAPK3,PTPRF,MAP3K4,TSC1,SNAP23,MAPK6,MAP3K5,MAPK1,HRAS |
| 4.074e-02 | -3.20 | CAPN2 (calpain 2) | protein interactions | 824 | 63 | 16 | 17029 | 2761 |
ATXN3,UBXN1,TUFM,UBE2I,TWF2,MAN2A2,GNS,GRK2,ATIC,NSFL1C,BCL2,GAS2,PCYT2,TATDN1,MAPK1,CAPN1 |
| 4.074e-02 | -3.20 | SLMAP (sarcolemma associated protein) | protein interactions | 7871 | 63 | 16 | 17029 | 2761 |
MOB4,CEP170B,STRIP1,STRN4,SIKE1,IRF3,CNTROB,PPP2CA,LIN9,PDCD10,PFDN4,CENPJ,PTAR1,ZRANB1,FGFR1OP2,PRPF19 |
| 4.074e-02 | -3.20 | CAMSAP2 (calmodulin regulated spectrin associated protein family member 2) | protein interactions | 23271 | 63 | 16 | 17029 | 2761 |
ZBTB21,CEP104,PCM1,NF1,CENPJ,DENND4C,KIF13B,KBTBD7,CDC25B,UBE2I,OAZ1,MARK2,GIGYF1,EEF1D,DCTN1,RTKN |
| 4.074e-02 | -3.20 | BRMS1 (breast cancer metastasis suppressor 1) | protein interactions | 25855 | 63 | 16 | 17029 | 2761 |
FOXK1,CUL3,DNAJB1,APP,MXD1,BRMS1,PFDN5,MBIP,HSPA4,E2F1,RBBP4,SINHCAF,SMARCE1,HDAC2,ARID4A,SAP30 |
| 4.074e-02 | -3.20 | PPFIA1 (PTPRF interacting protein alpha 1) | protein interactions | 8500 | 63 | 16 | 17029 | 2761 |
PTPRF,PPP2CA,MBIP,PSMD1,GPS2,PSMD8,CAST,TXLNA,AURKB,BRCA1,PPFIA3,ERC1,NCOA2,PSMC4,SPTAN1,CDC5L |
| 4.074e-02 | -3.20 | TAF6 (TATA-box binding protein associated factor 6) | protein interactions | 6878 | 63 | 16 | 17029 | 2761 |
ERCC1,KAT2A,PPP1R21,MBD3,APP,MAPK3,TAF2,USF1,CCNA2,CHD3,TBPL1,TAF12,RBBP4,TAF6,HDAC2,SAP30 |
| 4.079e-02 | -3.20 | tRNA binding | molecular function | GO:0000049 | 56 | 14 | 17224 | 2647 |
CTU2,METTL1,FARSA,KARS,IARS,TRMU,NSUN2,TYW5,MRPS27,IARS2,DTD1,EIF2A,EIF2AK4,TARS |
| 4.080e-02 | -3.20 | positive regulation of histone modification | biological process | GO:0031058 | 83 | 19 | 17256 | 2622 |
TGFB1,KAT2A,KMT2E,KAT7,MECP2,WBP2,RTF1,BRCA1,CCNB1,MAPK3,PAF1,AKAP8,OGT,CTR9,BRD7,RUVBL2,CHTOP,SMAD4,DNMT1 |
| 4.082e-02 | -3.20 | Small cell lung cancer | KEGG pathways | ko05222 | 84 | 20 | 7161 | 1149 |
MAX,BIRC3,AKT2,E2F3,XIAP,CYCS,BCL2L1,BIRC2,RXRB,RB1,PTEN,PIK3R2,E2F1,ITGB1,PIAS2,CDKN1B,BCL2,E2F2,TRAF5,CDK2 |
| 4.082e-02 | -3.20 | Small cell lung cancer | KEGG pathways | hsa05222 | 84 | 20 | 7161 | 1149 |
MAX,BIRC3,AKT2,E2F3,XIAP,CYCS,BCL2L1,BIRC2,RXRB,RB1,PTEN,PIK3R2,E2F1,ITGB1,PIAS2,CDKN1B,BCL2,E2F2,TRAF5,CDK2 |
| 4.086e-02 | -3.20 | LTBR (lymphotoxin beta receptor) | protein interactions | 4055 | 78 | 19 | 17029 | 2761 |
PLK1,CCDC93,BIRC3,ZMYND11,MAP4K4,TIGD5,MKI67,MAP7D1,SLTM,BIRC2,CD320,TRIM4,HGS,ODF2,PRC1,CISD2,TRAF5,ZC3H3,RNF114 |
| 4.089e-02 | -3.20 | GTP_EFTU | pfam domains | PF00009 | 18 | 6 | 17054 | 2545 |
EFL1,GUF1,GFM2,EFTUD2,GSPT2,TUFM |
| 4.089e-02 | -3.20 | zf-CCHC | pfam domains | PF00098 | 18 | 6 | 17054 | 2545 |
ZCCHC9,CPSF4,ZCCHC8,RBM4,TUT4,ZCCHC2 |
| 4.097e-02 | -3.20 | SCN3B (sodium voltage-gated channel beta subunit 3) | protein interactions | 55800 | 68 | 17 | 17029 | 2761 |
B3GALT6,UTP20,TMED7,TMEM115,INTS7,NF1,URB2,HSDL1,PDS5B,NOC2L,ABCD1,BCAP29,SLC35B2,OSTC,BCAP31,ZNF146,ABCC5 |
| 4.097e-02 | -3.20 | EIF5B (eukaryotic translation initiation factor 5B) | protein interactions | 9669 | 68 | 17 | 17029 | 2761 |
ZNF207,PRKAA1,ABCF2,MRPL12,CSNK2A1,BRCA1,SND1,ETS1,CPNE3,CAND1,PA2G4,C1orf131,CS,ANXA5,XRCC3,GPI,FTSJ3 |
| 4.097e-02 | -3.20 | NFE2L2 (nuclear factor, erythroid 2 like 2) | protein interactions | 4780 | 68 | 17 | 17029 | 2761 |
NCOR2,UBE2E2,NQO1,SUMO2,CUL3,SMARCA4,BRCA1,PMF1,MAP2K2,TRIM28,KEAP1,RBMX,MAFK,DCAF11,SIAH2,YY1,HDAC2 |
| 4.100e-02 | -3.19 | TOMM22 (translocase of outer mitochondrial membrane 22) | protein interactions | 56993 | 73 | 18 | 17029 | 2761 |
TOMM20,EWSR1,RPS10,HSDL1,ILF3,LAMTOR3,SLC35B2,ATP5F1B,SND1,TOMM40,VDAC1,HNRNPR,TIMM29,FAM3C,FEM1B,XRCC3,TECR,RAD51D |
| 4.100e-02 | -3.19 | USP20 (ubiquitin specific peptidase 20) | protein interactions | 10868 | 73 | 18 | 17029 | 2761 |
PLK1,RFC3,CLSPN,VHL,MAP7D1,ADRB2,PLEC,PRKACA,RFC2,USP21,LMNA,CCP110,MAPK6,USP20,NUP153,ACADM,LRRC59,ZNF770 |
| 4.101e-02 | -3.19 | GO_RESPONSE_TO_NITROGEN_COMPOUND | MSigDB lists | GO_RESPONSE_TO_NITROGEN_COMPOUND | 826 | 143 | 17377 | 2626 |
MAX,AGRN,SIRT2,MAPK14,BIRC2,CREM,EEF2K,CALM2,CDK5,USF1,RAB8A,RAP1A,DPYSL2,PIK3R2,DNM2,AKR1B1,UPRT,DNMT1,OGG1,CARM1,CDC5L,KLF10,AKT2,GNG7,EZR,CDC6,BRCA1,PRKRA,DHX15,SMAD2,TMED10,OGT,ATP6V0C,SMAD1,ATP6V0E1,HDAC2,SLC25A33,DDX58,AGTRAP,PRKAA1,SDC2,LAMTOR3,METTL3,SRRT,NDUFS4,PDXP,BDH1,EFTUD2,ATP6V0A2,BCL2,CYC1,GNAI2,ATP6V0D1,AACS,SRSF5,ADRB2,MTR,APPL1,IRF5,AKAP1,FAS,ADSS,CAT,GNAS,TSC1,CSK,MAP3K5,CDK2,ZC3HAV1,EGLN1,MBD1,DNMT3A,FOXM1,UBR2,UROD,WDTC1,RRAGC,IRF3,BCL2L1,ATP6V1B2,LYN,PRKACA,APP,GNB2,HNRNPA2B1,PDK2,ATP6V0B,NRF1,CCNA2,MDM2,SHC1,ATP2A2,RALB,ADCY9,CDKN1B,MAVS,AHCYL1,ADCY7,ATP6V1G1,BTG2,SLC26A6,ATP6V0A1,PSMB9,SOCS7,IDE,DGCR8,SCAP,STAT6,STAT1,TICAM1,PPP5C,MAPK1,LTA4H,FLOT1,BLM,AP3S1,CAPN2,PTPN2,HOMER1,PTEN,ARHGEF2,ANXA5,CREB1,STAT3,MYO5A,RNLS,PDPK1,PPP3CA,PPP1R9B,TNFAIP3,DENND4C,PRKDC,PRKAR1B,LDHA,RANGAP1,KCNQ1,MEN1,PDE3B,KLF6,MAPK3,ATP6V1D,ATP6V1C1,CPEB2 |
| 4.101e-02 | -3.19 | - | gene3d domains | 1.20.1540.10 | 9 | 4 | 8148 | 1295 |
PARL,RHBDD2,RHBDD1,RHBDF2 |
| 4.101e-02 | -3.19 | - | gene3d domains | 3.30.720.50 | 9 | 4 | 8148 | 1295 |
PARP12,HUWE1,ZC3HAV1,DTX4 |
| 4.103e-02 | -3.19 | centriole | cellular component | GO:0005814 | 130 | 27 | 18223 | 2701 |
BCCIP,FGFR1OP,FAM92A,FOPNL,POC1A,TOPORS,CNTROB,SIRT2,CCNF,HSPA1B,KIF2A,RAB8A,STARD9,CEP104,PCM1,CCP110,CENPJ,CEP55,ODF2,RP2,CEP63,ROCK1,WDR62,CFAP20,SASS6,POC5,DCTN1 |
| 4.105e-02 | -3.19 | GSE34217_MIR17_92_OVEREXPRESS_VS_WT_ACT_CD8_TCELL_DN | MSigDB lists | GSE34217_MIR17_92_OVEREXPRESS_VS_WT_ACT_CD8_TCELL_DN | 122 | 26 | 17377 | 2626 |
WSB2,PPAN,SNX27,CKLF,AACS,HMGXB3,MBLAC2,LYRM1,MAGED1,CAMSAP1,USP10,IL21R,EIF2S2,GOLGA2,CYB5RL,WDR4,FBXO7,FUT8,RPF2,QRSL1,GAS2,PDXK,NR2F2,TOP1MT,LMAN1,PLOD3 |
| 4.105e-02 | -3.19 | GSE25088_IL4_VS_IL4_AND_ROSIGLITAZONE_STIM_MACROPHAGE_DAY10_DN | MSigDB lists | GSE25088_IL4_VS_IL4_AND_ROSIGLITAZONE_STIM_MACROPHAGE_DAY10_DN | 196 | 39 | 17377 | 2626 |
GPR132,ST13,MDH2,HEXB,ATP6V1B2,DUSP22,SLC20A1,SF3B2,PHC2,NFATC3,VASP,MCM5,AHSA1,FOXN2,MDFIC,ST8SIA2,FAM171A1,CFL1,GPX4,CDC5L,NOL12,FAM49B,RAB7A,ERLIN1,WDHD1,MTMR6,MIER2,NFATC2,EIF4H,ARSK,BBS12,MYO1F,POLE,TFDP1,ADAM9,RBMS1,AKNA,PDLIM5,IGBP1 |
| 4.108e-02 | -3.19 | TNF signaling | REACTOME pathways | R-HSA-75893 | 43 | 12 | 10287 | 1696 |
ADAM17,CYLD,TNFAIP3,BIRC3,TAB2,RPS27A,XIAP,USP21,BIRC2,SPPL2B,FADD,SPPL2A |
| 4.114e-02 | -3.19 | GSE14415_INDUCED_TREG_VS_FAILED_INDUCED_TREG_DN | MSigDB lists | GSE14415_INDUCED_TREG_VS_FAILED_INDUCED_TREG_DN | 173 | 35 | 17377 | 2626 |
LIME1,CLSPN,SRGN,PTTG1,SDF2L1,RGS2,REEP5,RGS1,RABGAP1L,KIF14,LPIN2,RRBP1,F2R,MTPN,MYO5A,ACSL5,DDX28,TRAFD1,ELL2,PSMA1,BRCA1,SH3GLB1,ECH1,MYO1F,ABHD5,RAD54B,AHNAK,GADD45B,CDCA5,COX8A,ATF6,FKBP5,EHD4,GLCCI1,PFKP |
| 4.117e-02 | -3.19 | Hedgehog ligand biogenesis | REACTOME pathways | R-HSA-5358346 | 67 | 17 | 10287 | 1696 |
ADAM17,PSMA8,PSMB7,PSMA1,SYVN1,PSMB9,PSMD9,PSMB3,PSMC4,PSMD2,PSMA6,PSMD1,RPS27A,PSMD3,PSMD8,SEL1L,PSMC1 |
| 4.120e-02 | -3.19 | KH_dom | interpro domains | IPR004087 | 37 | 10 | 18492 | 2768 |
MEX3C,KHSRP,FXR1,PCBP1,ANKHD1,PCBP2,PNO1,AKAP1,KRR1,FUBP1 |
| 4.121e-02 | -3.19 | GO_TRANS_GOLGI_NETWORK_TRANSPORT_VESICLE | MSigDB lists | GO_TRANS_GOLGI_NETWORK_TRANSPORT_VESICLE | 27 | 8 | 17377 | 2626 |
RAB14,RAB8A,TMED10,GOPC,AP1S1,TGOLN2,CLTB,SYNRG |
| 4.121e-02 | -3.19 | SHIN_B_CELL_LYMPHOMA_CLUSTER_7 | MSigDB lists | SHIN_B_CELL_LYMPHOMA_CLUSTER_7 | 27 | 8 | 17377 | 2626 |
RB1,XRCC3,MAX,DVL1,PTEN,STAT6,IL6ST,PML |
| 4.121e-02 | -3.19 | GO_MODULATION_BY_SYMBIONT_OF_HOST_CELLULAR_PROCESS | MSigDB lists | GO_MODULATION_BY_SYMBIONT_OF_HOST_CELLULAR_PROCESS | 27 | 8 | 17377 | 2626 |
TGFB1,CCNK,KPNA4,KPNA1,KPNA2,EIF2AK4,BCL2L1,CPSF4 |
| 4.121e-02 | -3.19 | GENTILE_UV_LOW_DOSE_UP | MSigDB lists | GENTILE_UV_LOW_DOSE_UP | 27 | 8 | 17377 | 2626 |
CSNK1G2,CCDC86,SOX4,PPP1R8,BTG2,TOB1,ISG15,TAP1 |
| 4.121e-02 | -3.19 | MODULE_115 | MSigDB lists | MODULE_115 | 27 | 8 | 17377 | 2626 |
EIF5A,EIF3D,EIF4H,EIF4G2,PABPC1,EIF3G,EIF3H,EEF1D |
| 4.121e-02 | -3.19 | GO_NEUTRAL_LIPID_BIOSYNTHETIC_PROCESS | MSigDB lists | GO_NEUTRAL_LIPID_BIOSYNTHETIC_PROCESS | 27 | 8 | 17377 | 2626 |
AGPAT3,AGPAT2,LPCAT1,GPD1L,LCLAT1,LPIN2,LPCAT4,AGPAT1 |
| 4.121e-02 | -3.19 | KYNG_NORMAL_AGING_DN | MSigDB lists | KYNG_NORMAL_AGING_DN | 27 | 8 | 17377 | 2626 |
PWWP2A,GORAB,PPP1R12A,CLSPN,FAM172A,PTEN,PICALM,NUMB |
| 4.121e-02 | -3.19 | GO_SEX_CHROMOSOME | MSigDB lists | GO_SEX_CHROMOSOME | 27 | 8 | 17377 | 2626 |
SMC6,H2AFY,DNMT3A,H2AFZ,CDK2,SUZ12,BIRC2,H2AFX |
| 4.121e-02 | -3.19 | GO_POSITIVE_REGULATION_OF_TOR_SIGNALING | MSigDB lists | GO_POSITIVE_REGULATION_OF_TOR_SIGNALING | 27 | 8 | 17377 | 2626 |
RRAGC,TELO2,MIOS,WDR59,SEH1L,RHEB,MLST8,LAMTOR3 |
| 4.121e-02 | -3.19 | GO_POSITIVE_REGULATION_OF_TELOMERASE_ACTIVITY | MSigDB lists | GO_POSITIVE_REGULATION_OF_TELOMERASE_ACTIVITY | 27 | 8 | 17377 | 2626 |
MAP3K4,CCT2,AURKB,MAPK1,NVL,NEK7,POT1,MAPK3 |
| 4.121e-02 | -3.19 | GO_ACYLGLYCEROL_BIOSYNTHETIC_PROCESS | MSigDB lists | GO_ACYLGLYCEROL_BIOSYNTHETIC_PROCESS | 27 | 8 | 17377 | 2626 |
AGPAT3,AGPAT2,LPCAT1,GPD1L,LCLAT1,LPIN2,LPCAT4,AGPAT1 |
| 4.121e-02 | -3.19 | GO_PROTEIN_PHOSPHATASE_2A_BINDING | MSigDB lists | GO_PROTEIN_PHOSPHATASE_2A_BINDING | 27 | 8 | 17377 | 2626 |
ANKLE2,BCL2,SHC1,IGBP1,PPME1,STRN4,MASTL,ENSA |
| 4.121e-02 | -3.19 | Signal Transduction of S1P Receptor | WikiPathways | WP26 | 26 | 8 | 5312 | 837 |
ASAH1,RACGAP1,S1PR2,MAPK1,GNAI2,AKT2,MAPK6,MAPK3 |
| 4.128e-02 | -3.19 | 4 iron, 4 sulfur cluster binding | molecular function | GO:0051539 | 41 | 11 | 17224 | 2647 |
SDHB,NDUFV1,NDUFS1,PRIM2,POLE,TYW1,NDUFS8,NFU1,RSAD1,NDUFS7,TYW1B |
| 4.129e-02 | -3.19 | K63-linked polyubiquitin modification-dependent protein binding | molecular function | GO:0070530 | 22 | 7 | 17224 | 2647 |
WDR81,TNFAIP3,ZRANB1,PARP10,TAB2,RNF169,OPTN |
| 4.129e-02 | -3.19 | intramolecular oxidoreductase activity | molecular function | GO:0016860 | 51 | 13 | 17224 | 2647 |
MIF,GNPDA1,MRI1,ERO1A,TMX4,TMX3,PTGES3,GPI,PDIA6,QSOX2,TMX1,ECH1,EBP |
| 4.129e-02 | -3.19 | RNA polymerase core enzyme binding | molecular function | GO:0043175 | 51 | 13 | 17224 | 2647 |
PAF1,RRN3,BRD4,AGO2,ZNF326,DHX9,ELP4,CTR9,RTF1,TCOF1,RPRD1B,CDC73,ELOF1 |
| 4.132e-02 | -3.19 | AMIT_EGF_RESPONSE_240_HELA | MSigDB lists | AMIT_EGF_RESPONSE_240_HELA | 57 | 14 | 17377 | 2626 |
FARSA,THOC1,ELL2,VAV2,DLGAP4,EZR,RBMS1,YY1,RGS2,PDLIM5,LRP8,TUBGCP2,MAT2A,CREM |
| 4.139e-02 | -3.18 | human chr2q11.2 | chromosome location | human chr2q11.2 | 72 | 13 | 26185 | 2809 |
TMEM127,COX5B,ITPRIPL1,SNRNP200,MAP4K4,ARID5A,STARD7,CNOT11,CNNM3,ANKRD23,ANKRD39,PDCL3,TMEM131 |
| 4.143e-02 | -3.18 | PRDM5 (PR/SET domain 5) | protein interactions | 11107 | 39 | 11 | 17029 | 2761 |
SAP130,UPF1,ZFP91,RBM34,RPL8,RPF2,BRIX1,TNRC18,GAR1,FTSJ3,RPL36 |
| 4.143e-02 | -3.18 | UTP23 (UTP23, small subunit processome component) | protein interactions | 84294 | 39 | 11 | 17029 | 2761 |
RPS2,MPHOSPH8,DGCR8,HUWE1,KIF22,RRS1,APP,RBM4,RPSA,GPATCH4,DDX52 |
| 4.143e-02 | -3.18 | UGDH (UDP-glucose 6-dehydrogenase) | protein interactions | 7358 | 39 | 11 | 17029 | 2761 |
MAT2B,TKT,TGOLN2,GORASP2,UBE2V1,RNASEH2A,PDIA6,PRKACA,MAT2A,FAS,TERF2 |
| 4.143e-02 | -3.18 | WRAP53 (WD repeat containing antisense to TP53) | protein interactions | 55135 | 39 | 11 | 17029 | 2761 |
CCT2,PRPF38B,H2AFX,PRPF4,CNTROB,PTGES3,USP11,GAR1,POLG2,CCT8,RXRB |
| 4.143e-02 | -3.18 | PITRM1 (pitrilysin metallopeptidase 1) | protein interactions | 10531 | 39 | 11 | 17029 | 2761 |
BOLA3,NDUFV2,VASP,PRKCSH,COQ10B,LYRM1,MRPL12,LACTB,CHCHD2,SUCLG2,TERF2 |
| 4.143e-02 | -3.18 | COX6B1 (cytochrome c oxidase subunit 6B1) | protein interactions | 1340 | 39 | 11 | 17029 | 2761 |
NDUFV1,NDUFS1,POLR2G,TIMMDC1,SNAP29,ACOX1,COX7A2L,COX5A,NDUFA7,NDUFS4,XRCC5 |
| 4.143e-02 | -3.18 | POMP (proteasome maturation protein) | protein interactions | 51371 | 39 | 11 | 17029 | 2761 |
PSMD2,PSMA6,PSMB7,PSMA1,PSMG1,CUL1,UBE2V1,POMP,IGBP1,PSMB9,PSMB3 |
| 4.143e-02 | -3.18 | IGF2BP2 (insulin like growth factor 2 mRNA binding protein 2) | protein interactions | 10644 | 39 | 11 | 17029 | 2761 |
PA2G4,STAU1,CYLD,CCP110,ZNF746,CUL3,RBM3,TARDBP,MCM2,DCTN1,CAND1 |
| 4.143e-02 | -3.18 | BZW1 (basic leucine zipper and W2 domains 1) | protein interactions | 9689 | 39 | 11 | 17029 | 2761 |
CDT1,VAV2,LDHA,EIF5,CDK2,BZW2,KDELR1,CDC5L,ZMYM3,LDHB,DCTN1 |
| 4.143e-02 | -3.18 | COPG2 (coatomer protein complex subunit gamma 2) | protein interactions | 26958 | 39 | 11 | 17029 | 2761 |
STAU1,COPA,TMED10,MAGED1,COPE,PMS2,PTGES3,MCM2,COPG2,COPB2,CDC5L |
| 4.143e-02 | -3.18 | KEGG_PROSTATE_CANCER | MSigDB lists | KEGG_PROSTATE_CANCER | 89 | 20 | 17377 | 2626 |
PDPK1,NRAS,AKT2,RAF1,E2F3,KRAS,MAP2K2,MAPK3,RB1,MDM2,PTEN,PIK3R2,E2F1,CDKN1B,BCL2,CREB1,CDK2,MAPK1,E2F2,HRAS |
| 4.144e-02 | -3.18 | Chromodomain_CS | interpro domains | IPR023779 | 18 | 6 | 18492 | 2768 |
MPHOSPH8,SUV39H2,CHD3,CHD1,CBX4,CBX3 |
| 4.144e-02 | -3.18 | TF_GTP-bd_dom | interpro domains | IPR000795 | 18 | 6 | 18492 | 2768 |
EFL1,GUF1,GFM2,GSPT2,EFTUD2,TUFM |
| 4.176e-02 | -3.18 | pyridine-containing compound metabolic process | biological process | GO:0072524 | 116 | 25 | 17256 | 2622 |
GALK1,NADSYN1,MDH2,TKT,LDHA,NADK2,OGDH,ADPGK,PKM,PDHX,MPC1,PDXP,NAXE,DHTKD1,MDH1,PDXK,GPI,TALDO1,PARP10,GPD1L,PGAM1,PFKP,RNLS,KCNAB2,LDHB |
| 4.182e-02 | -3.17 | Regulation of Hypoxia-inducible Factor (HIF) by oxygen | REACTOME pathways | R-HSA-1234174 | 77 | 19 | 10287 | 1696 |
UBE2D3,PSMA8,RBX1,VHL,PSMB7,PSMA1,PSMB9,PSMD9,PSMB3,PSMC4,PSMD2,PSMA6,PSMD1,RPS27A,PSMD3,PSMD8,CITED2,PSMC1,EGLN1 |
| 4.182e-02 | -3.17 | Cellular response to hypoxia | REACTOME pathways | R-HSA-2262749 | 77 | 19 | 10287 | 1696 |
UBE2D3,PSMA8,RBX1,VHL,PSMB7,PSMA1,PSMB9,PSMD9,PSMB3,PSMC4,PSMD2,PSMA6,PSMD1,RPS27A,PSMD3,PSMD8,CITED2,PSMC1,EGLN1 |
| 4.189e-02 | -3.17 | regulation of DNA biosynthetic process | biological process | GO:2000278 | 105 | 23 | 17256 | 2622 |
DNAJC2,CCT2,RFC3,NEK7,CHTF18,PARP4,AURKB,MEN1,RFC2,PARN,CCT8,MAPK3,XRCC5,HNRNPA2B1,MAP3K4,NVL,NABP2,PTGES3,MAPK1,ARRB2,POT1,TERF1,TERF2 |
| 4.192e-02 | -3.17 | GSE2124_CTRL_VS_LYMPHOTOXIN_BETA_TREATED_MLN_DN | MSigDB lists | GSE2124_CTRL_VS_LYMPHOTOXIN_BETA_TREATED_MLN_DN | 179 | 36 | 17377 | 2626 |
WSB2,CCNC,PKP4,ANKRD13D,MANBA,MAGED1,KCTD17,IKBIP,SUPT7L,CCDC28A,DNAJB9,CHKA,LRRC14,ZNF473,LPIN2,GMEB1,DDX31,MDFIC,MAVS,PIKFYVE,HTRA2,JMJD4,GALC,NLN,GORAB,PRKRA,POLG2,HAUS8,WNT5B,CRCP,CHEK2,PIEZO1,EHD4,CHMP7,PDCD2L,ZNF511 |
| 4.192e-02 | -3.17 | GSE18804_SPLEEN_MACROPHAGE_VS_TUMORAL_MACROPHAGE_UP | MSigDB lists | GSE18804_SPLEEN_MACROPHAGE_VS_TUMORAL_MACROPHAGE_UP | 179 | 36 | 17377 | 2626 |
MAX,TRIP12,DBF4,ZNF107,NDUFA4,CSNK1A1,BECN1,MIEN1,NDUFS7,PAPOLA,MOAP1,SAP130,C1GALT1,KLHL5,PIKFYVE,CDK12,UBE2QL1,GCC2,ZNF559,KLF10,TNFAIP3,USP42,RPL6,RCOR1,FAM133B,SEPT7,PRKRA,PSMB9,ZFR,GLOD4,XRCC5,OPTN,GOLGA4,ETS2,STAT1,GLCCI1 |
| 4.192e-02 | -3.17 | GSE21063_CTRL_VS_ANTI_IGM_STIM_BCELL_NFATC1_KO_8H_UP | MSigDB lists | GSE21063_CTRL_VS_ANTI_IGM_STIM_BCELL_NFATC1_KO_8H_UP | 179 | 36 | 17377 | 2626 |
CCDC93,UBL3,ZBTB10,ANKRD13D,LUZP1,ARID5A,AGFG1,MXD4,CCNL2,FOXO3,CHD1,CHKA,CRY2,PIK3IP1,TP53BP2,ZRANB1,CNOT6L,ASB6,CDK12,TGFB1,PLK3,LONRF3,ETV3,RB1CC1,TOPORS,RBM38,FBXO21,LTBP4,ARNTL,PIAS2,RNF38,TRIM52,WDR91,ZBTB11,SMURF1,FAM83G |
| 4.192e-02 | -3.17 | GSE29618_LAIV_VS_TIV_FLU_VACCINE_DAY7_MONOCYTE_DN | MSigDB lists | GSE29618_LAIV_VS_TIV_FLU_VACCINE_DAY7_MONOCYTE_DN | 179 | 36 | 17377 | 2626 |
SRM,SART1,TRIP10,RAF1,STRN4,SDC2,CIB1,ACAP1,BRAP,SLC4A2,POLR3K,DDRGK1,FLAD1,VASP,SP100,ARF5,TAGLN2,FTSJ3,EIF5A,ENPP4,SGCE,DDX24,RTF1,OGDH,NDUFB1,MEN1,EIF3G,DDX23,WAS,SERF2,TWSG1,SAFB,CANT1,GPI,NRBP1,OAZ1 |
| 4.192e-02 | -3.17 | GSE17974_2.5H_VS_72H_IL4_AND_ANTI_IL12_ACT_CD4_TCELL_UP | MSigDB lists | GSE17974_2.5H_VS_72H_IL4_AND_ANTI_IL12_ACT_CD4_TCELL_UP | 179 | 36 | 17377 | 2626 |
CCDC93,UBL3,IER2,NAT9,C9orf78,NOP2,CAST,ZNF416,RRAGC,NIPA2,SLC25A44,RAPGEF6,CREM,SYNM,ZNF746,ZNF200,CDK12,TMBIM1,NXT1,MAPRE2,GTPBP4,MTMR6,TOLLIP,GAR1,ABCF1,IWS1,DERL1,SPATA2,C1orf109,DUSP11,CHMP7,SMURF1,GPATCH4,ATMIN,ADNP2,TMEM33 |
| 4.193e-02 | -3.17 | RASD2 (RASD family member 2) | protein interactions | 23551 | 21 | 7 | 17029 | 2761 |
LRP5,SMAD2,SMAD1,SMURF1,SMAD4,GNB2,RAF1 |
| 4.193e-02 | -3.17 | MICAL3 (microtubule associated monooxygenase, calponin and LIM domain containing 3) | protein interactions | 57553 | 21 | 7 | 17029 | 2761 |
MYH9,KIF23,RACGAP1,CAPZA2,ANLN,PICALM,MYO18A |
| 4.193e-02 | -3.17 | IL6R (interleukin 6 receptor) | protein interactions | 3570 | 21 | 7 | 17029 | 2761 |
FANCL,ADRB2,STAT3,IL6ST,FAAP100,PPP1R21,WWP2 |
| 4.193e-02 | -3.17 | CKMT1A (creatine kinase, mitochondrial 1A) | protein interactions | 548596 | 21 | 7 | 17029 | 2761 |
GALK1,VDAC1,SLC25A5,PGAM1,GPD1L,SUZ12,CUL3 |
| 4.193e-02 | -3.17 | DHX40 (DEAH-box helicase 40) | protein interactions | 79665 | 21 | 7 | 17029 | 2761 |
USP7,JMJD6,FUS,MTHFD2,SPDL1,TERF2,IARS2 |
| 4.193e-02 | -3.17 | BOLA2 (bolA family member 2) | protein interactions | 552900 | 21 | 7 | 17029 | 2761 |
COX15,VDAC1,MCM2,EIF4A3,ARRB2,PARK7,CUL3 |
| 4.193e-02 | -3.17 | EIF2AK4 (eukaryotic translation initiation factor 2 alpha kinase 4) | protein interactions | 440275 | 21 | 7 | 17029 | 2761 |
SMAD1,ARRB2,SMAD4,MATR3,TARS,LRPPRC,TKT |
| 4.193e-02 | -3.17 | TCIRG1 (T cell immune regulator 1, ATPase H+ transporting V0 subunit a3) | protein interactions | 10312 | 21 | 7 | 17029 | 2761 |
RPS15,DDX28,EWSR1,ATP6V1D,SYNCRIP,ATP6V0D1,TERF1 |
| 4.193e-02 | -3.17 | RABL3 (RAB, member of RAS oncogene family like 3) | protein interactions | 285282 | 21 | 7 | 17029 | 2761 |
FGFR1OP,RHOA,APP,GPR89A,EVC2,PTAR1,TMEM216 |
| 4.193e-02 | -3.17 | LRRC46 (leucine rich repeat containing 46) | protein interactions | 90506 | 21 | 7 | 17029 | 2761 |
AMZ2,INO80E,POLE,HJURP,LRSAM1,PACS2,HADHB |
| 4.193e-02 | -3.17 | KLF16 (Kruppel like factor 16) | protein interactions | 83855 | 21 | 7 | 17029 | 2761 |
CTR9,WASF2,NASP,SYNCRIP,BLM,POLK,HUWE1 |
| 4.193e-02 | -3.17 | LSM14A (LSM14A, mRNA processing body assembly factor) | protein interactions | 26065 | 21 | 7 | 17029 | 2761 |
CSNK2A1,SYNCRIP,HNRNPDL,STRAP,AHSA1,RAE1,CIRBP |
| 4.193e-02 | -3.17 | CDCA2 (cell division cycle associated 2) | protein interactions | 157313 | 21 | 7 | 17029 | 2761 |
JMJD6,KPNA2,IER2,NUP153,BRCA1,EWSR1,MBD4 |
| 4.193e-02 | -3.17 | SEPT4 (septin 4) | protein interactions | 5414 | 21 | 7 | 17029 | 2761 |
SEPT8,SEPT11,SEPT1,SEPT7,BIRC3,SIAH1,XIAP |
| 4.193e-02 | -3.17 | TUBA3E (tubulin alpha 3e) | protein interactions | 112714 | 21 | 7 | 17029 | 2761 |
CCT2,PFDN5,MCM2,CD81,PFDN4,VHL,TIMM50 |
| 4.193e-02 | -3.17 | SLC30A4 (solute carrier family 30 member 4) | protein interactions | 7782 | 21 | 7 | 17029 | 2761 |
NOP9,RBM25,EIF5,CIP2A,MLST8,C19orf25,PDS5B |
| 4.193e-02 | -3.17 | VAMP7 (vesicle associated membrane protein 7) | protein interactions | 6845 | 21 | 7 | 17029 | 2761 |
ANKRD27,SIRT2,AGFG1,DNAJC5,RAB11A,SNAP29,SNAP23 |
| 4.193e-02 | -3.17 | RIC8B (RIC8 guanine nucleotide exchange factor B) | protein interactions | 55188 | 21 | 7 | 17029 | 2761 |
GNAS,MAGED2,NAP1L1,GNAI2,CAMKMT,TIGD5,ENSA |
| 4.193e-02 | -3.17 | CEP83 (centrosomal protein 83) | protein interactions | 51134 | 21 | 7 | 17029 | 2761 |
MYH9,USP7,DVL1,PSMC1,HMG20A,FGFR1OP2,SH3GLB2 |
| 4.193e-02 | -3.17 | UQCRFS1P1 (ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1 pseudogene 1) | protein interactions | 100128525 | 21 | 7 | 17029 | 2761 |
ACAT1,USP7,SRSF3,SEPT9,EYA2,IDH3A,LAMTOR3 |
| 4.193e-02 | -3.17 | PDAP1 (PDGFA associated protein 1) | protein interactions | 11333 | 21 | 7 | 17029 | 2761 |
CSNK2A1,CLTB,HUWE1,APP,LMNA,IFI16,RBM8A |
| 4.193e-02 | -3.17 | TMEM120A (transmembrane protein 120A) | protein interactions | 83862 | 21 | 7 | 17029 | 2761 |
AGPAT3,NCLN,ATP5F1B,METTL9,VKORC1,B4GALT3,SNAP29 |
| 4.193e-02 | -3.17 | SUPV3L1 (Suv3 like RNA helicase) | protein interactions | 6832 | 21 | 7 | 17029 | 2761 |
RBM3,RBM42,HNRNPDL,ZMAT3,CUL3,CDC5L,HNRNPF |
| 4.193e-02 | -3.17 | WDR43 (WD repeat domain 43) | protein interactions | 23160 | 21 | 7 | 17029 | 2761 |
NAP1L1,FBL,UTP4,RBM4,IFI16,MAPK3,CERK |
| 4.193e-02 | -3.17 | K8 (bZIP transcription factor) | protein interactions | 4961462 | 21 | 7 | 17029 | 2761 |
SLBP,DDX28,ZCCHC10,ZCCHC9,CCDC59,HDAC2,C1orf122 |
| 4.193e-02 | -3.17 | SIK3 (SIK family kinase 3) | protein interactions | 23387 | 21 | 7 | 17029 | 2761 |
PPP3CA,YWHAZ,SMAD2,PRKACA,TAB2,YWHAH,PRKAA1 |
| 4.193e-02 | -3.17 | NANOS2 (nanos C2HC-type zinc finger 2) | protein interactions | 339345 | 21 | 7 | 17029 | 2761 |
CNOT9,CNOT6,CNOT6L,CNOT11,GPBP1L1,MAP4K4,CNOT3 |
| 4.193e-02 | -3.17 | STT3A (STT3A, catalytic subunit of the oligosaccharyltransferase complex) | protein interactions | 3703 | 21 | 7 | 17029 | 2761 |
CSDE1,KRAS,USF1,HJURP,KRTCAP2,HAUS2,TFEB |
| 4.197e-02 | -3.17 | IVANOVA_HEMATOPOIESIS_STEM_CELL_AND_PROGENITOR | MSigDB lists | IVANOVA_HEMATOPOIESIS_STEM_CELL_AND_PROGENITOR | 629 | 111 | 17377 | 2626 |
TMEM106C,CCDC93,ZBTB10,UBE2E2,TP53RK,PDCD6IP,ATXN3,IVNS1ABP,MCCC1,INO80E,MRPL19,ZNF275,MEAF6,CREM,NEK6,GLIS2,ETV6,TXLNA,INTS12,RHBDD2,FGFR1OP2,POC5,CCAR1,RLIM,PRPF19,RHOBTB3,GABPA,GOPC,MIER2,IL12RB1,SLC17A5,SOX4,ARL5B,SLC50A1,FKBP3,TMEM201,ALKBH6,GEMIN5,ANKZF1,MAN2A2,HSPA4,PDRG1,GADD45B,NRM,BAZ1B,DHTKD1,TRIM32,PTPDC1,SMAD1,PDCD4,PTOV1,SLC12A7,CTU2,DNAJC2,PKP4,KRBA1,SESTD1,VAV2,CERK,MXD4,ASXL2,FZD6,DNAJB9,WDR48,SLC25A36,FKBP1A,GSTK1,ITGB8,COQ4,HUWE1,SEC24C,FUT8,ZNF260,ZNF326,DAPK1,MSH2,ARHGEF2,BCL2,KIFAP3,PIK3IP1,ACAD8,IFT46,KDELR1,TERF2,ABCC1,NIPSNAP1,HP1BP3,GINS1,GTF3C6,HMGN5,ANKRD37,KAT2A,RBM42,ABCF2,ACSL3,MFNG,BMS1,LRRC1,CBFA2T2,CHCHD6,EPRS,FBXO21,MAPK6,PGRMC1,ZMIZ1,BTBD10,NR2F2,HEXA,IGBP1,IPO4,BYSL |
| 4.198e-02 | -3.17 | CD4 (CD4 molecule) | protein interactions | 920 | 109 | 25 | 17029 | 2761 |
ANXA6,EIF3D,RPS10,VDAC2,ATP6V0A1,ADRB2,VDAC1,MAPK14,RPS9,TFRC,RPSA,CD320,HNRNPA2B1,HGS,SIVA1,LRPPRC,RPLP1,ATP6V0A2,DDX5,ATP5F1A,GNAI2,CD81,TUBB,KCNAB2,SSRP1 |
| 4.208e-02 | -3.17 | Budding and maturation of HIV virion | REACTOME pathways | R-HSA-162588 | 25 | 8 | 10287 | 1696 |
CHMP2A,CHMP4A,PDCD6IP,RPS27A,CHMP4B,VPS4A,CHMP2B,CHMP7 |
| 4.208e-02 | -3.17 | APC-Cdc20 mediated degradation of Nek2A | REACTOME pathways | R-HSA-179409 | 25 | 8 | 10287 | 1696 |
CDC16,CDC27,RPS27A,ANAPC7,ANAPC2,CDC23,UBE2C,ANAPC4 |
| 4.208e-02 | -3.17 | Gap-filling DNA repair synthesis and ligation in GG-NER | REACTOME pathways | R-HSA-5696397 | 25 | 8 | 10287 | 1696 |
RPA2,PCNA,RFC3,POLE,POLK,RPS27A,RFC2,RPA1 |
| 4.208e-02 | -3.17 | RAF activation | REACTOME pathways | R-HSA-5673000 | 25 | 8 | 10287 | 1696 |
PPP2CA,NRAS,PPP2R5A,RAF1,BRAP,KRAS,HRAS,MAP2K2 |
| 4.209e-02 | -3.17 | Ras signaling in the CD4+ TCR pathway | Pathway Interaction DB | tcrraspathway | 11 | 5 | 2226 | 426 |
ELK1,MAPK1,RAF1,MAPK3,PTPN7 |
| 4.216e-02 | -3.17 | CAGCTTT,MIR-320 | MSigDB lists | CAGCTTT,MIR-320 | 243 | 47 | 17377 | 2626 |
UBE2D3,RHOG,TRIM41,SMAP1,PLXNC1,TRAF7,ADAM10,TSC22D3,ZFP91,MECP2,GSPT2,YTHDF3,PCSK7,KLF13,CDK13,PPP1R16B,TFRC,WRNIP1,CALM2,FKBP1A,RAP1A,NSRP1,ARPC5,TRMU,SPTSSA,LUC7L2,PLK3,FTL,FAM49B,ELL2,MIER1,ATXN1,MCL1,DHX15,MAT2A,NCDN,TPD52L2,RAB18,TSC1,RAD18,TFE3,ZC3H7B,OGT,USP20,CAB39,YWHAZ,MAPK1 |
| 4.225e-02 | -3.16 | TTCYRGAA_UNKNOWN | MSigDB lists | TTCYRGAA_UNKNOWN | 308 | 58 | 17377 | 2626 |
INTS2,HSPH1,RECQL,ABCA3,EWSR1,ST13,DNAJB2,DYNLL1,JMJD6,SLC4A2,XPNPEP3,CDIPT,MAP1LC3B,IL21R,PAPOLA,FBXO5,CDK5,HNRNPA2B1,APLP2,NFATC3,VMP1,RNFT1,PIK3R2,TRA2B,UPF2,NUP153,MTPN,NUDC,SRPK2,MTA2,LYRM1,TLK1,ATP2C1,WBP2,ELP4,ARHGEF12,DNAJA1,KCNQ1,LRRC1,ZNF407,CCT8,RAB2B,MAT2A,PHF6,EVC2,CBX3,KRIT1,CXXC4,PON2,RAB18,SYNCRIP,BRD2,RAB24,CCDC6,TPP2,E2F1,CLU,TMEM33 |
| 4.225e-02 | -3.16 | GO_POSITIVE_REGULATION_OF_PROTEIN_BINDING | MSigDB lists | GO_POSITIVE_REGULATION_OF_PROTEIN_BINDING | 73 | 17 | 17377 | 2626 |
MAPRE1,ADD1,MFNG,FLOT1,PACS1,MEN1,PARK7,EPB41,KRIT1,DERL1,CDK5,FKBP1A,RALB,HIPK2,ZNF268,TICAM1,PLCL2 |
| 4.225e-02 | -3.16 | REACTOME_G_ALPHA1213_SIGNALLING_EVENTS | MSigDB lists | REACTOME_G_ALPHA1213_SIGNALLING_EVENTS | 73 | 17 | 17377 | 2626 |
RHOG,RHOA,NET1,RHOC,GNG7,RAC1,TRIO,ARHGEF12,GNB2,RHOB,VAV1,GNA12,CDC42,ARHGEF1,PIK3R2,ARHGEF2,ROCK1 |
| 4.230e-02 | -3.16 | ruffle | cellular component | GO:0001726 | 165 | 33 | 18223 | 2701 |
DDX58,WASF2,RAC1,CIB1,MYH9,ARFIP2,NCKAP1,ATP6V1B2,PIP5K1C,PDXP,RINL,DNM2,ARHGEF2,S100A6,MYO5A,CFL1,PPP1R9B,CYFIP1,RHOA,ADAM17,MKLN1,ARHGAP45,AKT2,EZR,WIPF1,MACF1,RAB22A,ARF4,KIF18A,ITGB1,ROCK1,C2CD5,ALS2 |
| 4.234e-02 | -3.16 | Shigellosis | KEGG pathways | hsa05131 | 64 | 16 | 7161 | 1149 |
WASF2,RHOG,RAC1,ARPC1A,MAPK14,MAD2L2,MAPK3,CRKL,WAS,CDC42,ARPC5,ELMO1,ITGB1,ACTB,ROCK1,MAPK1 |
| 4.235e-02 | -3.16 | GO_TRANSCRIPTIONAL_REPRESSOR_ACTIVITY_RNA_POLYMERASE_II_ACTIVATING_TRANSCRIPTION_FACTOR_BINDING | MSigDB lists | GO_TRANSCRIPTIONAL_REPRESSOR_ACTIVITY_RNA_POLYMERASE_II_ACTIVATING_TRANSCRIPTION_FACTOR_BINDING | 52 | 13 | 17377 | 2626 |
POU3F2,HIPK2,PITX1,ARNTL,WBP2,SMARCA4,MEF2A,NCOA1,CREB1,SOX4,CITED2,TRIM28,WWP2 |
| 4.235e-02 | -3.16 | KEGG_AMYOTROPHIC_LATERAL_SCLEROSIS_ALS | MSigDB lists | KEGG_AMYOTROPHIC_LATERAL_SCLEROSIS_ALS | 52 | 13 | 17377 | 2626 |
CAT,DERL1,PPP3CA,RAC1,PPP3R1,BCL2,CYCS,BCL2L1,PPP3CB,TOMM40,MAP3K5,MAPK14,ALS2 |
| 4.239e-02 | -3.16 | cellular response to gamma radiation | biological process | GO:0071480 | 27 | 8 | 17256 | 2622 |
MDM2,TMEM109,H2AFX,BCL2L1,CHEK2,ELK1,HRAS,XRCC5 |
| 4.239e-02 | -3.16 | positive regulation of cell cycle G2/M phase transition | biological process | GO:1902751 | 27 | 8 | 17256 | 2622 |
DTL,RAD51C,BRD4,MECP2,CDC25B,CCNB1,APP,RAB11A |
| 4.239e-02 | -3.16 | regulation of spindle assembly | biological process | GO:0090169 | 27 | 8 | 17256 | 2622 |
PLK1,CHMP4B,CHMP2A,SMC3,PDCD6IP,CHMP2B,SPAG5,HSPA1B |
| 4.239e-02 | -3.16 | positive regulation of protein targeting to membrane | biological process | GO:0090314 | 27 | 8 | 17256 | 2622 |
CDK5,AKT2,ANK3,CIB1,C2CD5,CHP1,MIEF1,PRNP |
| 4.239e-02 | -3.16 | establishment of spindle orientation | biological process | GO:0051294 | 27 | 8 | 17256 | 2622 |
ARHGEF2,NDE1,SPDL1,MCPH1,MAP4,SAPCD2,SPAG5,DCTN1 |
| 4.246e-02 | -3.16 | Brix | smart domains | SM00879 | 6 | 3 | 9493 | 1367 |
RPF2,PPAN,BRIX1 |
| 4.246e-02 | -3.16 | DUSP | smart domains | SM00695 | 6 | 3 | 9493 | 1367 |
USP20,USP11,USP32 |
| 4.246e-02 | -3.16 | GAS2 | smart domains | SM00243 | 6 | 3 | 9493 | 1367 |
DST,GAS2,MACF1 |
| 4.246e-02 | -3.16 | RAP | smart domains | SM00952 | 6 | 3 | 9493 | 1367 |
FASTKD3,TBRG4,FASTK |
| 4.246e-02 | -3.16 | SMC_hinge | smart domains | SM00968 | 6 | 3 | 9493 | 1367 |
SMC3,SMC2,SMC4 |
| 4.249e-02 | -3.16 | human chr1q32.3 | chromosome location | human chr1q32.3 | 31 | 7 | 26185 | 2809 |
DTL,NENF,PPP2R5A,RPS6KC1,INTS7,TRAF5,TATDN3 |
| 4.249e-02 | -3.16 | protein localization to mitochondrion | biological process | GO:0070585 | 78 | 18 | 17256 | 2622 |
TIMM8B,TOMM20,MTX3,TIMM21,MTX1,DNAJA1,TOMM40,MFN2,MOAP1,TIMM13,HSPA4,TIMM23,TIMM17A,TIMM29,FBXO7,PITRM1,MTX2,TIMM50 |
| 4.254e-02 | -3.16 | GSE27291_0H_VS_7D_STIM_GAMMADELTA_TCELL_UP | MSigDB lists | GSE27291_0H_VS_7D_STIM_GAMMADELTA_TCELL_UP | 162 | 33 | 17377 | 2626 |
PWWP2A,USP7,TBC1D12,GOLIM4,GMFG,NCK1,XIAP,MOGS,WIPF1,ATG2B,SLC35B1,DUSP22,TOLLIP,RGS1,ABHD5,DDX17,TERF2IP,RAB21,NRF1,GOLGA4,FBXO28,ZNF700,BBX,MLYCD,DHTKD1,GAS2,WDR91,BEND6,BTBD10,ZNRD1,MGAT5,NCOA2,S100PBP |
| 4.266e-02 | -3.15 | GSE40273_EOS_KO_VS_WT_TREG_DN | MSigDB lists | GSE40273_EOS_KO_VS_WT_TREG_DN | 185 | 37 | 17377 | 2626 |
ZBED3,USP7,MIF4GD,H2AFZ,GXYLT1,VAV2,HMGN3,CDK13,EIF2AK4,S1PR2,ETS1,LYN,GIT2,STARD9,METTL14,RCSD1,ANP32A,CISD2,CNN2,VOPP1,ARHGAP17,GOPC,KIAA0930,NFATC2IP,ASB13,GAR1,OPTN,VEZF1,CORO1C,CDCA5,ATE1,FKBP5,NCOA1,FAM208A,USF2,TMEM131,LRCH1 |
| 4.266e-02 | -3.15 | CYCLIN_D1_KE_.V1_UP | MSigDB lists | CYCLIN_D1_KE_.V1_UP | 185 | 37 | 17377 | 2626 |
TCF12,PPIB,HSPH1,TSC2,THOC1,DAP,TRIO,KLC1,PPP3CB,REEP5,STAM,BIRC2,CHKA,KIFC1,INPP5A,LPIN2,KIF22,TTLL12,GNAI2,PHKG2,MGAT5,KCNAB2,EIF5A,PLK3,PRRC2A,ATXN1,HSPA1B,MAN2A2,ETS2,STT3A,SCAP,AXIN1,E2F4,FAM3C,DMWD,PPP5C,CDKN2A |
| 4.266e-02 | -3.15 | GSE39022_LN_VS_SPLEEN_DC_UP | MSigDB lists | GSE39022_LN_VS_SPLEEN_DC_UP | 185 | 37 | 17377 | 2626 |
UBL3,FEZ2,TMBIM4,B4GALT5,DBF4,FLOT1,C5orf30,KIF23,ORC1,MXD1,CCP110,MCM5,MBD2,PRDM4,SLC38A10,FNIP2,LRRC59,ELOF1,GINS1,ACSL5,TXNL1,PTPN18,TACC1,DENND4C,NUP155,NFATC2,ESYT1,CCNF,PWWP2B,PDCD6,MID1IP1,UAP1,RAD18,PALB2,CHMP4B,KPNA2,PGAM1 |
| 4.266e-02 | -3.15 | GSE2770_IL12_VS_IL4_TREATED_ACT_CD4_TCELL_6H_UP | MSigDB lists | GSE2770_IL12_VS_IL4_TREATED_ACT_CD4_TCELL_6H_UP | 185 | 37 | 17377 | 2626 |
NAT14,C1orf74,ZBTB10,TOMM20,KDM4A,USP39,COMMD5,RLF,MAP1LC3B,CMTM6,PARK7,FKBP1A,XRCC2,AFF1,RNASEH2A,MRPL11,MCMBP,ABI1,UBE2M,GPX4,WDR41,CSRP1,NSDHL,RNPS1,KCTD20,BRMS1,TBC1D17,FNTA,ERGIC3,WDR4,C1orf109,MLYCD,SLC25A19,RUVBL2,BTF3,GPI,OAZ1 |
| 4.266e-02 | -3.15 | GSE9960_GRAM_NEG_VS_GRAM_POS_SEPSIS_PBMC_DN | MSigDB lists | GSE9960_GRAM_NEG_VS_GRAM_POS_SEPSIS_PBMC_DN | 185 | 37 | 17377 | 2626 |
ZNF496,CDC40,TMX4,AP1B1,AP3S1,ABHD14A,RPN1,COQ4,ZNF302,RAB4A,MSH2,ANP32A,CNOT6L,CLN6,SLC35A1,TPCN1,PTPN18,TIMMDC1,DENND4C,TUFM,ATP6V0A1,MTMR12,MAP4K3,ARHGDIB,RHOB,DTWD1,TRAM2,ATP6V1D,PCM1,EXOC4,IARS2,FN3KRP,MEGF9,TRIM52,CLN3,CHPT1,HEXA |
| 4.266e-02 | -3.15 | GSE17721_CPG_VS_GARDIQUIMOD_6H_BMDC_UP | MSigDB lists | GSE17721_CPG_VS_GARDIQUIMOD_6H_BMDC_UP | 185 | 37 | 17377 | 2626 |
MAX,PTTG1,C5orf30,RRAGC,HMGN3,SDF2L1,NOTCH2,CHAC2,CSNK1A1,PCBP1,RGS1,RBM17,TFAP4,CDKN2C,PELO,SOCS6,H2AFY,MRPL54,TRA2B,TFG,RPL22L1,DVL2,PPIF,BIRC3,SNX2,TMEM39A,RFXANK,C1orf35,OGFR,CAND1,HLA-B,SIAH2,NCOA1,NAA20,PLOD3,IGBP1,PRPF4B |
| 4.266e-02 | -3.15 | GSE3982_EOSINOPHIL_VS_EFF_MEMORY_CD4_TCELL_UP | MSigDB lists | GSE3982_EOSINOPHIL_VS_EFF_MEMORY_CD4_TCELL_UP | 185 | 37 | 17377 | 2626 |
RAB14,REPS2,RPS6KA1,TKT,MEF2A,GGA2,SNN,ATP6V1B2,RLF,PSEN1,CHD1,MBD4,SNRNP25,CTSS,RALB,ETV6,TPST1,DAPK1,JOSD1,DDX31,PIKFYVE,MAML1,ORAI2,ABHD2,AGGF1,BRD4,RHOBTB3,CREG1,SELPLG,CRNKL1,ISG15,PSMC4,MID1IP1,SH3GLB2,ZMIZ1,RTN3,NAA60 |
| 4.277e-02 | -3.15 | TGF-beta receptor signaling activates SMADs | REACTOME pathways | R-HSA-2173789 | 34 | 10 | 10287 | 1696 |
TGFB1,FKBP1A,SMAD2,MTMR4,RPS27A,UCHL5,SMURF1,UBE2M,STRAP,SMAD4 |
| 4.277e-02 | -3.15 | Termination of translesion DNA synthesis | REACTOME pathways | R-HSA-5656169 | 34 | 10 | 10287 | 1696 |
RPA2,PCNA,RFC3,POLE,POLK,RPS27A,USP10,RFC2,ISG15,RPA1 |
| 4.277e-02 | -3.15 | SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription | REACTOME pathways | R-HSA-2173796 | 34 | 10 | 10287 | 1696 |
CCNC,CCNK,SMAD2,RBL1,RPS27A,E2F4,TFDP1,TFDP2,MEN1,SMAD4 |
| 4.277e-02 | -3.15 | human chr2p13.2 | chromosome location | human chr2p13.2 | 13 | 4 | 26185 | 2809 |
FBXO41,PRADC1,SPR,SFXN5 |
| 4.278e-02 | -3.15 | UBR4 (ubiquitin protein ligase E3 component n-recognin 4) | protein interactions | 23352 | 104 | 24 | 17029 | 2761 |
MOB4,LARS,SNRNP200,BIRC3,FOXK1,NCK1,SRGN,UBXN1,METTL2A,RANGAP1,AURKB,MCM2,KCMF1,BIRC2,RAD23A,RB1,USF1,EFTUD2,ACLY,XRCC3,SASS6,ECPAS,FAF1,SRPK2 |
| 4.278e-02 | -3.15 | GO_REGULATION_OF_DEPHOSPHORYLATION | MSigDB lists | GO_REGULATION_OF_DEPHOSPHORYLATION | 145 | 30 | 17377 | 2626 |
TGFB1,ANKLE2,PPP1R37,ZCCHC9,PPP1R2,PPP1R12A,UBN1,GBA,ENSA,CDCA2,PAWR,WDR81,PKMYT1,PPP1R16B,SYMPK,MASTL,AKAP1,FKBP1A,CALM2,TSC1,PPP2R5A,PPME1,PIN1,PPP1R11,CRY2,ROCK1,PPP6R3,IGBP1,PPP2R2D,PPP6R1 |
| 4.288e-02 | -3.15 | stomach | COSMIC cancer mutations | stomach | 16028 | 2407 | 17385 | 2587 |
HECA,ZBTB10,ABCC10,HEXB,TGOLN2,CCNL2,FBXO22,EEF2K,THAP4,RAD23B,ATP13A3,DNM2,ZNRD1,FTSJ3,USP34,CCDC57,ERCC1,NRAS,EHMT1,KIF15,HNRNPF,WDHD1,MIER2,DIDO1,MCM2,RAB22A,SMAD2,MID1IP1,RPS27A,MYO18A,OGT,MPV17,SMAD1,ZNF75A,ANXA11,ZNF720,SEC61G,GGA1,MUM1,CCZ1,TRIO,CUTA,RAB23,KCTD17,HAUS4,EIF2AK4,APH1B,PARN,CDC73,MYL6B,ATG4A,TMEM179B,ERV3-1,PDXP,SMC3,GEMIN4,MVP,NUP85,PPP6R1,PABPC1,NSUN4,PPA1,IFRD1,AGGF1,FOXK1,RBM42,GTPBP4,MAP7D1,MRPL16,ELK1,EIF4H,RDH11,MAGED2,KPNA1,ETS2,TYW5,WIPI2,RUFY3,PDLIM5,ACSF2,RHOG,EXOC3,STARD7,VTI1A,C5orf30,INO80E,SLC35B2,LCLAT1,RCOR3,CPNE3,KIAA1147,RBM23,ZNF420,AHCTF1,TBC1D22A,TBC1D14,GMEB1,NSFL1C,SEPT11,ZNF226,GPD1L,ZC3H3,ARL5A,PDCL3,SNX8,ERMP1,IDH3A,HTATIP2,MEF2D,TMEM147,GSTCD,TANC1,MAT2A,VPS26B,CORO1C,NSMCE2,CAMKMT,PPP5C,PITRM1,TUBB,COMMD10,ZNF445,HABP4,CCM2,FLOT1,BTN3A1,ATG2B,ABHD14B,PPP1R3B,GOLM1,ZBTB45,HUWE1,ZNF260,NAA50,ANXA5,LTN1,UBE3B,NAP1L4,ZNF710,ST8SIA2,RPL22L1,SPTAN1,STAU1,TCTEX1D2,DDX24,TACC1,MRS2,LDHA,HEBP2,RAB3IP,TTC33,PICALM,SH3BP5,SLC19A1,ACOX1,FAM3C,AEN,PARP10,YWHAH,THAP5,GPATCH4,FAM129A,TRIM11,YTHDC2,SNX15,RBM8A,NENF,SND1,RUFY1,TRIM65,ZER1,PRNP,KRR1,RAB8A,NUP210,NT5DC1,NOC2L,EIF5,TACC3,VPS13B,RYBP,PTPN18,MIOS,SNRPB,MBLAC2,CDC6,UTP3,PBRM1,ODC1,USP21,TRAM2,FBXO28,BCL7C,ARRDC1,ADAM9,DVL1,NUMB,ZNF564,C1orf74,CTU2,PARP12,ZCCHC9,CENPF,CHCHD2,NCKAP1,RSAD1,TNS3,SUB1,RINL,SSBP3,KIF13B,MBD2,XPA,AHCY,RBM3,GLE1,MRPL48,LRSAM1,HDHD2,NTPCR,NSDHL,AMD1,CAMSAP1,ZNF761,METTL22,ICAM2,STYXL1,APPL1,BBS12,ANKRD46,RXRB,SDHB,PCM1,GALNT2,TMEM168,NLRC5,RUVBL2,BTBD10,MYO9A,CCNB2,USP7,GLT8D1,RPLP2,SUCLG1,ARID2,TMX4,SLC2A1,ATP6V1B2,PCBP1,LYN,VAV1,TMEM69,MRPL50,PSMA6,ZNF473,ZNF302,BRPF3,TARDBP,BCAP29,CTDSP2,PRPF19,PPIF,KDM3B,MND1,CLCN3,BIRC3,RAB7A,ANKRD33B,PPIE,CHMP2B,VDAC1,EIF3H,TMEM201,GLOD4,IDE,DHX16,UHRF2,CHMP4B,XRCC3,PARD3,BCL2L12,MCM10,C19orf53,KLHL21,PDAP1,CDCA8,TMX3,GTF3A,ARF1,SLC12A9,TUBGCP2,DNAJB9,HOMER1,WBP1L,POLR1B,RNF5,RBM15B,PPAN,RHOA,RPRD1A,BTAF1,TOP3A,ARHGEF12,PCGF1,DDX23,RAB18,CACNB1,TRIM26,PDCD6,ATP6V1D,L3MBTL3,FAM110A,NEIL3,CTBS,BBX,IMPDH1,TAF12,NR2F2,HIPK3,IFI16,TXN,NUP188,H2AFZ,PNISR,TMEM203,PRKCSH,USP39,UBE2I,SLC25A37,ASPHD2,ZNF428,RAB4A,TRA2B,SUCLG2,TAF5L,ZNF800,CDC5L,ZNF524,SGCE,OSBP2,NSUN2,USP22,CLNS1A,EIF3A,ZMYM3,DOT1L,IWS1,ANKRD10,WAS,KIF18B,TPP2,C1orf109,ZMAT3,B4GALT2,PRPF38B,RECQL,C9orf78,EWSR1,RRM1,ACAP1,B4GALT1,FAM136A,SUPT7L,TMEM165,NPLOC4,CNOT3,SPAG5,WDR48,RTKN,CEP104,EXOSC7,KLHL5,LRRC8D,MSH2,PIGG,OSTF1,FBXL7,MRPL40,TNRC18,SYTL3,FAM171A1,APOL1,EIF5A,GCC2,PRIM2,ELL2,RDH10,MFNG,RPS24,GORASP2,CAPZA2,ADRB2,CCT8,MTR,PHF6,PFDN5,SLCO4A1,TTC13,GOLGA2,RBMX,MED15,PIAS2,APPL2,SAMD8,NUDT3,CDKN2A,ZNF511,ATXN3,RAF1,KIAA0232,C2orf49,EPM2A,CD320,CCNA2,MTMR4,TP53BP2,AQR,RBM12B,ILKAP,CDK12,SAP30,BRD4,DRAP1,NARF,LRRC8A,ELP4,ABHD11,PKMYT1,ASB13,TRIM28,SUPT16H,EIF3K,CHMP4A,CBWD1,ATF6,XRCC4,ADAM23,PRPF4B,NDUFS1,DEPDC1,MECP2,SECISBP2,HMG20A,WWP2,JAKMIP1,SLC25A36,CCNK,DNAJC8,ELP5,AXIN2,CITED2,JMJD4,KAT2A,TMEM126B,RABIF,ADSL,PACS1,BMS1,KCNQ1,OTUD3,ARSK,MACF1,KIF11,COMMD4,KLF6,SMAP2,FADD,SH3GLB1,MYO1F,CBX3,TMEM127,INF2,PPP1R11,DUSP11,DDX5,WDR62,TAF6,ESPL1,PURA,DDB1,DEF6,IPO4,FAM83G,UBL3,NAT9,PIGM,LYRM4,GPR132,UBE2Q1,PTP4A3,BRIX1,MRPL19,ZNF696,SF3B2,PCYOX1L,CDC42,SYNM,GOT2,JAZF1,HADHB,RPF2,SLC35C2,CNNM3,CARM1,SRPK2,WDR41,LARS,ZCCHC10,CCDC138,LRBA,TMEM216,SUMF2,KMT2C,OGFR,PRPSAP1,ASF1B,RPL37,MAN2A2,EIF4ENIF1,U2SURP,MIA2,ZNF268,VPS4A,PPP1R2,PM20D2,XPNPEP3,RGS2,LYAR,FAM89B,POLR2I,TRAFD1,SUGP2,GBA,EIF2A,SYVN1,DAPK3,ARHGAP15,MASTL,UAP1,NFIL3,FN3KRP,YWHAZ,CTSA,TOB1,TSEN15,ADNP2,TCF12,PRKAB1,MDH2,SMARCA4,ORC1,RRN3,UBXN2A,IARS,CD3EAP,KIF14,EXOSC1,CS,CLTB,DNAL4,CSTF1,POU2AF1,UBQLN4,NXT1,HPDL,PGGT1B,SELPLG,SMU1,ATXN1,GLO1,OGDH,BICD2,CADM1,EDEM2,HERPUD2,TOLLIP,FANCE,MBD3,PDHX,RPS9,ALKBH6,SURF4,DUS3L,ARNTL,ANP32E,FKBP5,TMEM101,CCDC125,ABCA1,PDCD2L,GCLM,RAE1,DCTN2,NUP54,CHIC2,MXD4,DCUN1D4,PIP4K2A,XPR1,FERMT3,KIF5B,KLHL20,SEC24C,RRBP1,ARHGEF2,ANP32A,LDLRAD3,STAT3,MYO5A,NIPAL3,TXNL1,PHF20L1,DCAF6,FAM49B,TMEM39A,ATP2C1,RFFL,COG1,RCOR1,PRMT2,TFEB,LEMD2,UPF1,ELMO1,ZC3H7B,DTX4,ZMIZ1,TERF1,HRAS,CCDC93,FGFR1OP,PIGQ,AGPAT1,CNTROB,PPP1R16B,GSDMB,TTC9C,PDS5B,NUP153,SENP1,PGAP2,TMEM115,PLEKHM3,DCUN1D5,PLEKHF2,BRMS1,PWWP2B,TRIM47,WDR11,AXIN1,SMG9,TRIM52,LONP2,NDUFV2,PHF23,CERK,SLC4A2,EZH1,ITGB5,LMNA,MCTS1,DDX56,EIF2S2,SLC38A5,FOXN2,CARS2,PRRC2A,C16orf72,RB1CC1,ZMYND11,PGS1,MYBL2,UHRF1BP1,SRSF5,MPG,MATR3,CYB5A,NCDN,POLR2J,SETD3,TEX30,PTAR1,CNOT6,NDE1,EGLN1,ZNF207,ANKRD27,ABCA3,SARNP,IVNS1ABP,RMI2,MON1B,TMEM97,NIT2,NUF2,ZNF267,TCF19,TMEM161B,KTN1,APP,PRKD3,CLUAP1,ATP2A2,UTP18,GRSF1,DUT,ZCCHC2,ANAPC7,RNF19A,FAM76B,CLN6,TMEM9,GCC1,RNF169,ADCY7,ATP6V1G1,ENPP4,CDCA2,FKBP3,GPR137,DDX17,CHCHD3,PEX5,CDC16,HIPK2,MBOAT1,TICAM1,PDXK,ZBTB11,ANXA6,TMBIM4,GMCL1,UBE4A,ETS1,WRB,ZNF92,PNO1,CAPN2,ADD3,SUV39H2,TTLL12,TPCN1,TMX1,LYPLA2,HNRNPM,MFSD12,LDHB,PPP3CA,POLK,JTB,EMP3,MTMR12,ZP3,PDE3B,KIF18A,CCDC6,MAPK6,C4orf46,LY75,SLC25A19,RGL1,PSAP,WDR76,IGBP1,FAF1,COX15,THOC1,AGRN,GNPDA1,GPBP1L1,PPP1R15B,CSNK2A1,EBNA1BP2,GIT2,BIRC2,ATPAF1,DLG5,ABL2,XRCC2,ZFYVE27,MCMBP,PTPRK,CDC37,SP3,METTL1,HARS,GMFB,ESYT1,ANLN,RAB5B,RHEB,DPYSL3,TBC1D17,CDCA4,TONSL,NRM,NAGLU,ACTB,ZNF45,TMUB1,CTCF,ASAH1,DOCK11,CRLF3,ASXL2,LRRC14,NUS1,SLC27A4,AFF1,MDFIC,MAML1,CYTH1,NQO2,UTP15,EIF2AK1,EIF4G2,ZDHHC3,MOSPD3,ITPRIPL1,CDC27,SNAP23,TBPL1,PRMT7,KCTD7,CYLD,UGP2,COPE,HCFC1R1,ZADH2,GGPS1,RPAIN,RAD23A,ATP6V0B,PDK2,STRBP,DUS4L,MRPL34,PDCD2,SAP30L,SLC39A9,CLPTM1,RPL29,RPL35,DNAJC9,MTMR6,FRAT2,NFATC2,KDM1B,ARL5B,USP36,CCDC127,MRPL2,ATP1A1,CLK3,PSMD3,MAFK,CEP55,NDUFA11,DNAJC17,ZNF436,NCOA1,SLC25A39,ZC3HC1,ZNF146,ATXN7L2,CDC40,GOLIM4,SMAP1,RRP15,DAP,GNE,SMC6,ARFIP2,NKRF,CHAC2,BZW2,WRNIP1,PTGES3,CAMK2G,MLEC,ZNF202,PPWD1,FAM50B,RHOT2,NEU1,TPD52L2,GOLGA7,PGRMC1,GLG1,FAM126A,RPS6KC1,UBE2C,PPCS,NDUFB6,TMEM41B,ZDHHC8,PLXNA1,CCNB1,SLC20A1,COMMD6,ABHD14A,POLR3K,ASAP2,SNUPN,CNPY4,PLCL2,TFG,SEH1L,ATG9A,PBK,MKI67,DDX20,AMDHD2,SLC17A5,GALNT7,CCNF,FOXRED1,RBM47,PTER,WDR4,DHTKD1,TRAF5,HDAC2,PWWP2A,HSPH1,MAPRE1,CHTF18,ADO,KIF23,SLC35B1,NOTCH2,PMF1,JMY,FKBP1A,SNX18,CTPS1,ATP6V0A2,PIKFYVE,LPCAT1,EEF1D,TMED2,FTL,PHF10,DDX28,ZNF84,SIGMAR1,PIP4K2C,FAM133B,RIT1,PLEC,KDM3A,SF3A2,FAS,EPRS,ZNF777,TMEM54,QARS,TCOF1,CABLES1,NRBP1,DNMT3A,RWDD1,CKLF,TRIP10,SF3B1,CAST,SUZ12,RPS6KA1,RAC1,OLA1,SNN,GNB2,FLAD1,APLP2,KDM2A,CDKN1B,TNPO2,TALDO1,ATP13A1,RFC3,MAPRE2,ERF,CUL3,SLBP,KIAA1586,H2AFV,GAR1,PSMB9,POLG2,DHX57,NSA2,HSPA4,MRPL55,JAK1,GOLGA8A,TBL3,SEL1L,H2AFX,KLHDC4,B4GALT3,PDCD11,ATMIN,POLQ,POU3F2,OTUD5,NCOR2,ANKRD13D,PKP4,SCAMP3,BABAM1,CDCA3,SLC25A12,BLM,TMCC3,GTF2F1,RPL17,CRAT,AHSA1,PRC1,UPF2,COPS7B,SLC38A10,CNOT6L,CNPY3,UBE2M,IFT46,TSHZ1,ZFP64,STRIP1,DENND4C,DENND1B,WDR18,RPL8,ILF3,LRRC1,RHOT1,MARK2,TSR2,ECH1,PRDX1,PLD3,NUCB1,GNA12,FBXO21,C1orf131,PRDX3,PFDN4,HNRNPH3,TFDP1,STX18,KHSRP,ASNA1,CPEB2,VPS29,BYSL,S100PBP,MIB2,IER2,PTMS,NOP2,UBN1,DCAF15,NF1,FLYWCH2,ALKBH5,MOGS,UBE2Z,TAF6L,BECN1,MAPK14,SNAPC4,RNF103,BCAT2,MBD4,METTL14,IMPAD1,ZNHIT6,RCSD1,PHTF1,SRI,KIF22,ZBTB22,OGG1,TRIM14,ELOF1,COPS8,FYTTD1,TRIM8,RRM2,SOX4,CXXC4,UBTF,PAF1,UEVLD,SPATA2,PQBP1,IARS2,ATXN2L,GALNT10,STARD3NL,PIGN,AGTRAP,CIB1,XPO7,SRRT,ZNF449,CAPZA1,GLTP,KIFAP3,BCL2,N4BP2,HP1BP3,VOPP1,THNSL1,ISG15,CAND1,GNAS,TSC1,RBM25,ZFP90,NANP,RBBP4,ZBTB24,SMARCD1,MBD1,WASF2,MMACHC,TOMM20,IFI27L1,GNPNAT1,MPHOSPH8,HNRNPUL2,CHD1,MEAF6,C2orf68,CCDC50,AKAP8,PARL,RPN2,CHTOP,FAM3A,F2R,TMEM14C,SCYL3,ABI1,HTRA2,MOSPD1,RLIM,FAM172A,ZNF500,PSMB7,NLN,WIPF1,BOLA1,BUD13,NDUFB1,PEF1,EIF3G,BTBD1,TAB2,CHCHD1,TULP3,WDR59,CANT1,SCARB1,GAS2,USP11,SMURF1,TSPAN5,PPP2R2D,CDS2,MAGEH1,MRPL42,EYA1,MRPS26,LETMD1,KLF13,HDDC2,RGS1,MAN1A1,FBXO5,GART,PELO,TANK,BRD7,SAMD4B,ZDHHC18,GTF3C6,POLR3GL,WDR81,MEN1,ZNF407,MFN2,ZRANB2,SRSF3,MBD6,ATP6V1C1,IDH3B,TATDN1,TSC2,LACTB2,CMTM6,RBM4,ZNF275,ANKRD39,RPL23A,CDKN2C,NAPG,USF1,DNAAF2,MECR,AP1M1,UPRT,CRY2,ECD,RNF26,TIPARP,LRRC59,ANKRD9,RHBDD2,MGAT5,BAK1,ZNF559,RHOBTB3,GABPA,NUTF2,ARF4,GINS4,KRIT1,AHNAK,RAD18,PDRG1,RNASEL,CHPF2,PDCD4,SMNDC1,NXT2,HIVEP3,KIAA0100,CLSPN,RHOC,DHX9,PDCD7,HAUS2,COPB2,TFAP4,CD59,RNFT1,MEGF8,RIMS3,EFTUD2,FBXO7,CPSF4,MRPL21,PHKG2,LUC7L2,EIF3L,MTA2,TYW1,USP10,ITM2A,SSR2,BCLAF1,SFXN5,FNTA,PDLIM1,TXNDC16,ZNF830,TMEM159,MRPL3,ALS2,TRIM41,KARS,NQO1,POC1A,ANK3,PTTG1,TPX2,TBC1D13,DAZAP2,GLRX3,STMN1,C19orf48,REPS1,ABHD16A,FBXL6,SH3BP1,MTA1,UBA5,CLCN6,INTS12,RPRD1B,SZRD1,CGGBP1,CPNE1,SEC61B,FAM118B,GOPC,E2F3,RPL38,CRNKL1,PFKFB3,GORAB,GIGYF1,TMEM184C,PPP2CA,KIF2A,CCDC14,RNF38,SNRPG,CENPBD1,DMWD,USP13,MZT1,ZFP91,TRMT6,IP6K2,WDR5,SLC25A43,PMVK,NEIL2,RRP36,SRXN1,RPA2,PSMD2,CLIC4,PDCD10,CBWD2,COQ4,ITGB8,ARF5,ARHGEF1,FBXL19,TTPAL,UTP20,MAGT1,GPS2,DBI,MRFAP1L1,CD81,TMEM131,WDR13,FANCI,PAPOLA,CREM,FANCL,TET3,GLIS2,IL6ST,INTS1,SLC44A1,MTPN,ASB6,PLK1,RPP25,CELSR2,SEPT9,RBX1,APH1A,RAD51AP1,CKAP2L,PSMG1,UBE2V1,EAF2,IL12RB1,LUC7L,LSG1,NECAP2,ALG3,TRIM4,AGPAT2,CHD3,ZNF367,E2F4,PRPF4,KPNA2,BEND6,CLN3,DNAJC30,FAM208A,NGLY1,POT1,MYL12B,CCDC137,RMND5A,HJURP,PHB2,DNAJB2,FAM53C,NKD2,SDC2,KLC1,CDK13,ADCK5,COX4I1,DNAJB1,RAB6A,ARID1B,C1GALT1,MLX,UBE2Q2,CCP110,ZNF746,ARL6IP1,CTR9,NIPSNAP1,ABHD2,DCAF8,ACSL3,LDB1,MAP4K3,ARMC8,RBM38,NMT2,IRF5,RPL36,HAUS8,MBIP,ORMDL2,COX7A2L,ZDHHC7,SIL1,FAM122A,DTD1,UNC13C,BCCIP,SART1,TRAF7,TOR1AIP1,ZNF416,LAGE3,TM9SF3,ZFYVE21,RRAGC,ZNF121,NRF1,WDR44,PPME1,RPAP1,CABLES2,LMAN1,AHCYL1,TOP1MT,STRAP,SPSB3,ZNF583,SNX25,ARHGAP17,POLR2G,ZNF780B,PPT1,NUP155,DCLRE1C,MRPS14,RHBDF2,SUGP1,RBL1,FASTK,UBXN2B,STK38,AP1S1,SPRYD4,SLC22A23,H3F3A,CHID1,SMAD4,RAD51D,SLC30A9,UNK,CMAS,NADSYN1,HMGN3,NCAPG,SCYL2,FZD6,HERC3,GTPBP3,CTSS,ORC3,RNLS,YTHDC1,ACP2,HMGN5,CSRP1,ABCF2,TUFM,RANGAP1,PNPLA8,HAGH,API5,ZFR,SEC23IP,E2F1,TMEM219,USP20,RBPJ,PDCD6IP,MAX,GXYLT1,LUZP1,ADAM10,CXXC1,TSC22D3,AP3M2,CUL1,GYG1,NANS,OAT,MYEF2,ANKRD26,PA2G4,NOL11,FIZ1,ZNF200,MARCH2,SLC26A2,SRSF10,SRP72,KLF10,LACTB,RFC2,RAB2B,PRIM1,MAP3K4,HHEX,LUC7L3,RPS14,MAP4,MRPL27,BTF3,PTPDC1,NMD3,CCDC59,PTOV1,DNAJC5,DHPS,POLR2K,ANKH,PRKAA1,VAV2,GSPT2,TATDN3,DLGAP4,PXMP2,PRPF39,PSEN1,ZNF79,PDXDC1,NDUFS7,YY1AP1,C12orf10,FAM192A,RPN1,LHX8,ZNRF2,TPST1,DAPK1,PIK3IP1,CYC1,SOCS5,FDFT1,PIGT,EMB,WDR1,ZNF574,C1orf35,EXOSC9,ARID1A,PTTG1IP,C9orf40,FXR1,GOSR1,MAP2K2,TWISTNB,AKAP1,XRCC5,HMGN2,PI4K2A,CAT,DERL1,MTHFD2,HSPBP1,CEBPG,ARAP1,USP32,FAM83D,CABIN1,SMPD4,GPI,CYTIP,TP53RK,REPS2,RAB11B,UROD,SLC39A13,POMP,NUDT19,DECR1,RALB,SIAH1,ADCY9,LPIN2,MRPS27,SOCS6,TTC3,RNASEH2A,CFL1,ANKLE2,CDC123,OAF,EDF1,EML4,ERC1,AMZ2,ANKZF1,ZNF282,DSN1,DDOST,DGCR8,SAFB,HAGHL,FTSJ1,RWDD4,LMBR1,NCLN,BEND3,EYA2,DYNC1LI2,MANBA,B4GALT5,SLC41A1,FAM76A,TKT,CBLL1,ARGLU1,LANCL1,POFUT1,FAM8A1,HEATR5B,HLA-A,EBP,RFWD3,NDUFA2,FJX1,FUT8,BTF3L4,PTPN11,FEM1B,RPL19,CNN2,NDUFA3,MTX2,MSH6,PDLIM2,LONRF3,RFXANK,FBXO9,GUF1,ZHX1,NDUFS5,WDR91,GPR89B,POLA2,ZNF76,MTX3,COPA,UQCR10,PHRF1,HMGXB3,ABCB10,COMMD5,MAP1LC3B,DST,RAB35,SIVA1,GPATCH1,TCEA1,DRAM2,DEAF1,TRAPPC13,SNRNP200,LAP3,NCK1,VHL,SREK1,ARHGDIB,PITPNB,HSPB11,BRWD1,PPM1G,SH3GLB2,CRCP,BAZ1B,ACBD4,STK11,CLU,CHEK2,ZSWIM3,TSTD2,MRPL13,CHPT1,DCAF5,CAPN1,UBE2D3,PPP1R12A,ZCCHC8,GORASP1,NACA,UBXN1,RPL15,EPN1,PCSK7,THRAP3,QSOX2,TTF1,PRPF18,NUP205,CHKA,DTL,MED10,ZRANB1,SLC12A2,ATP6V0D1,CSNK1G3,CREG1,RPL6,VKORC1,SLTM,EVC2,KLHL15,SIAH2,SLC16A1,EHD4,SNRNP70,C11orf1,APOL2,N4BP2L2,CHMP2A,CORO7,FEZ2,UCK2,PMS2,UCK1,CLCC1,EXT2,MXD1,USP5,HNRNPA2B1,SAP130,NVL,PPP6C,CYB5R1,ZNF770,EBAG9,RNF25,PCGF6,METTL2A,FAM72B,PON2,HNRNPR,HPS5,STAT6,MAPK1,BRD9,TMEM33,DNAJC2,TRIP12,SHPRH,SCYL1,VPS45,MYO9B,GFM2,SPPL2A,FASTKD3,FGFR3,MZT2A,PPIG,TMEM99,H2AFY,NDUFS8,ATG13,ERI3,FBL,FRMD8,SLC35A1,MICAL3,TGFB1,B3GALT6,ELOVL5,HEMK1,TIMMDC1,HELB,PSPC1,MIER1,SCFD2,NDRG3,CDK11A,MEGF9,ACAT1,CENPT,PLOD3,RAB3IL1,ZSWIM6,RAB14,ADD1,KDM4A,MRPS15,XIAP,DHX8,GLUD1,ANKRD23,PABPC4,CDK5,CALM2,PSMD1,NEK6,NSRP1,RABGAP1L,SRSF4,FNIP2,KCNAB2,PCBP2,MLST8,PLK3,ZNF672,MRPL43,HSDL1,MCL1,PPFIA3,SMC2,ICMT,SLC50A1,STOML2,LIMK1,ZNF689,PRDX5,ATE1,MLYCD,ST3GAL2,ATP6V0C,FBXL3,TFDP2,E2F2,PFKP,AAAS,DDX42,SSRP1,MRPL9,MRPS2,STRN4,TOP2B,ZNRF3,TMED3,DDRGK1,RAVER2,GNS,INTS7,INPP5A,MCM5,PHF14,ZNF326,NAGPA,TIMM8B,TSPYL4,TSPAN31,DHX29,TEX10,MAN1B1,CBFA2T2,ABCF1,RHOB,LRRC14B,DTWD1,PTPRF,SCARB2,OSBPL11,CCDC86,DUSP3,SLAIN1,MDH1,HEXA,RNF139,SNX14,ZNF296,TRERF1,UBR2,CHD1L,ACTR3,WDTC1,MYH9,NIPA2,PRKACA,SAFB2,ANKIB1,STAM,ARL6IP6,RAB21,SP100,ZKSCAN1,DDA1,NUP107,ANKRD13C,MAVS,CEP63,ATF2,DCTN1,SHOC2,PSRC1,MAP4K4,WBP2,ATP6V0A1,NUSAP1,DNAJA1,TAZ,TAF2,C19orf54,SEC61A1,RPLP1,WDR7,CBLN2,FUS,GEN1,LRP8,COIL,LRCH1,GALK1,ZNF786,RPS2,SESTD1,TRAK1,JMJD6,SIKE1,KRI1,FBXO3,GATC,NDUFB4,PPP1R8,PRDM4,GTSE1,DCP1A,SGCB,S100A6,IMPA2,NUDC,PDPK1,TK1,GUK1,TNFAIP3,GALC,ZNF512,KIAA0930,MRPS10,DDX39A,RPA1,ZNF180,ZNF862,KEAP1,POLE,TATDN2,PITX1,CAPN7,LRPPRC,PML,HMGB2,USF2,ANAPC4,SRM,DDX47,MCCC1,CDC42SE2,S1PR2,CDIPT,SEC16A,SSR1,LIN9,PCNA,ZNF639,TRMU,ETV6,PIK3R2,TXLNA,PPCDC,MYBL1,MRPL32,CCAR1,ABCC5,PBXIP1,BAZ2A,TLK1,MRPL12,EZR,LNX2,LRP5,BRCA1,PRKRA,STX16,EPB41,OPTN,SEPT1,SOCS4,QRSL1,PIEZO1,OSGEPL1,GLCCI1,NUDT11,NAA60,GEMIN7,SEPHS2,LZTR1,RACGAP1,PPP3CB,B4GALT4,RLF,RAPGEF6,RB1,VASP,MED8,VMP1,PPIL2,TIMELESS,AHDC1,ALDH18A1,TMEM8A,ABCC1,PREB,TRAPPC9,AACS,MEMO1,KRAS,RTF1,UBE4B,NFATC2IP,LY6E,ARPC1A,ZNF174,PSMC4,GOLGA4,PALB2,SYNCRIP,PRPS2,NIPA1,TIGD2,FOXM1,MRPL39,XAB2,DUSP22,COMMD8,RPL11,CSDE1,MDM2,CORO1A,METTL9,MINPP1,POC5,DVL2,GM2A,PSMA8,COQ10B,CPOX,TIGD5,SLC26A6,CYP20A1,PRPF3,RPSA,SRSF1,DNAJC10,ZNF700,SCAP,PLEKHG4B,TIMM17A,LTA4H,AP2S1,USP53,INTS2,CTDP1,MIF4GD,CDT1,ARID5A,SUMF1,GGA2,AP3S1,CSNK1A1,RMI1,TFRC,PTPN2,STARD9,GSTK1,NDUFV1,SLC1A4,CWC27,SLC35B4,DDX31,ABCD1,RPAP3,CNTN5,SNX2,ZMYM5,CHCHD6,BSDC1,KPNA4,FBXO41,BIRC5,TFE3,SNAP29,CDCA7L,PKD2,ACADM,CHMP7,GCSH,ZNF496,TMEM109,TAP1,YTHDF3,NHLRC3,ELMOD2,KIFC1,DBNDD1,CYB5RL,PARPBP,RNASEK,CDC25B,PRADC1,DNMT1,ORAI2,USO1,AKT2,NOL8,GNG7,AURKB,MCFD2,SLC25A5,ZFAND5,MAK16,STT3A,TMED10,PSMD8,EIF2D,ITGB1,PTPN7,UQCRH,RRS1,ARRB2,RTN3,ZNF598,DDX58,WSB2,PPIB,MUT,GMFG,HLA-E,MAN2B1,METTL3,CFLAR,NDUFS4,RNF121,MEX3C,KLF16,HDAC7,BDH1,PCYT2,GNAI2,ANKHD1,MORC3,TERF2,KCTD20,SEPT8,DCTD,PKM,TOMM40,PATL1,ADSS,SERTAD2,SERF2,NSF,ERGIC3,ACLY,LPCAT4,VCPIP1,YY1,PPP6R3,PPP6R2,MAP3K5,RNF14,CDK2,ZC3HAV1,SYS1,URB2,EIF3D,MAGED1,KLHL18,ADPGK,SLC25A44,AP1B1,SDHA,PAIP2,PHC2,CRKL,TERF2IP,MOAP1,CYHR1,ZNF75D,SHC1,UCHL5,NAA35,TMBIM1,CCT2,CDKN2AIP,MKLN1,HMGN4,LYRM1,GALK2,CDC23,SHCBP1,AP4E1,PRDM11,VEZF1,PPP2R5A,ACYP1,STAT1,PPA2,TRIM32,RHEBL1,R3HCC1L,C1orf112,TCF3,MRI1,BRAP,AGPAT3,MYNN,SDF2L1,SPR,RAB11A,REEP5,FOXO3,MAD2L2,CCDC28A,PIP5K1C,RBM17,MAT2B,PTEN,CENPJ,TAGLN2,PACS2,NCOA2,SMC4,RNASEH2C,NEK7,NET1,PARP4,TBRG4,ANAPC2,YIF1A,SGSH,HGS,TTLL4,SLC38A7,MFAP1,CCDC69,BRWD3,ESYT2,SKA3,NPHP4,UBE2E2,HNRNPAB,PLXNC1,TMEM184B,ST13,ZNF107,KIF2C,SLC29A1,AGFG1,SIRT2,FKBP2,USP48,SNRPD3,UBQLN2,CUTC,EDC3,UBLCP1,ZNF804A,RAP1A,THADA,EIF4A3,AP3S2,ATG3,DPYSL2,PPP1R12C,AKR1B1,NDUFB9,JOSD1,RP2,TTC4,TECR,ARID4A,FGFR1OP2,TIMM50,TDP1,DPM1,FOPNL,SLC16A7,SLC25A22,STK17B,DHX15,CHAF1A,GEMIN5,COPS6,SASS6,PSMC1,SLC12A7,TBC1D12,TM9SF4,ZNF768,MED13L,TIA1,MEF2A,EPHX2,PITHD1,RHBDD1,NFATC3,BANF1,ZNF335,BUD31,YBX1,KNTC1,ACAD8,UBE3C,ZNF189,ALDH9A1,KDELR1,TSTA3,CIC,OXR1,SEPT7,NAP1L1,NSMF,ODF2,EXOC4,KIAA1328,NUP62,PITPNA,NAA20,PTDSS1,PDSS2,C7orf26,TMEM106C,IMMT,ASH1L,CHERP,WDYHV1,PLAGL2,CHKB,IRF3,TWF2,PAIP1,ANKRD28,ANKLE1,FARSA,SAR1A,SCAMP4,APOOL,PDIA6,ACSL5,TOR1AIP2,AZI2,RAD54B,TMEM41A,DAP3,ZNF317,GADD45B,AKNA,REEP4,CBX4,MIF,KIF3B,GOLPH3L,SH2D3A,CASP6,TOR3A,SRGN,DBF4,MFSD10,SAC3D1,CTNNBL1,YIF1B,CLDND1,TTC17,SLC25A1,GINS1,PAQR6,CSNK1G2,TELO2,ADAM17,NASP,ASPM,PPP1R21,PRKAR1B,SYMPK,TARS,SNRPA,MAPK3,HLA-B,ATAD2,PLAA,ZNF330,OSBPL8,KBTBD7,PREPL |
| 4.289e-02 | -3.15 | Regulation of nuclear SMAD2/3 signaling | Pathway Interaction DB | smad2_3nuclearpathway | 76 | 21 | 2226 | 426 |
MAX,KAT2A,TCF3,CBFB,ITGB5,FOXO3,SMAD2,RBL1,TFE3,TFDP1,MED15,DCP1A,NCOA1,RBBP4,CREB1,CDK2,ATF2,SMAD4,NCOA2,HDAC2,SAP30 |
| 4.290e-02 | -3.15 | GO_REGULATION_OF_CENTROSOME_DUPLICATION | MSigDB lists | GO_REGULATION_OF_CENTROSOME_DUPLICATION | 32 | 9 | 17377 | 2626 |
CHMP2A,PDCD6IP,CENPJ,CHMP4B,XRCC3,BRCA1,CHMP2B,CCNF,GEN1 |
| 4.290e-02 | -3.15 | LIANG_HEMATOPOIESIS_STEM_CELL_NUMBER_SMALL_VS_HUGE_DN | MSigDB lists | LIANG_HEMATOPOIESIS_STEM_CELL_NUMBER_SMALL_VS_HUGE_DN | 32 | 9 | 17377 | 2626 |
CYTH1,C4orf3,GADD45B,PTTG1,DNAJA1,PDCD7,POLG2,WDR48,S100A6 |
| 4.290e-02 | -3.15 | HU_GENOTOXIC_DAMAGE_24HR | MSigDB lists | HU_GENOTOXIC_DAMAGE_24HR | 32 | 9 | 17377 | 2626 |
MTHFD2,SLC1A4,IARS,BANF1,H2AFX,DNAJA1,ALDH18A1,EIF1B,ISG15 |
| 4.290e-02 | -3.15 | GO_KERATAN_SULFATE_METABOLIC_PROCESS | MSigDB lists | GO_KERATAN_SULFATE_METABOLIC_PROCESS | 32 | 9 | 17377 | 2626 |
GNS,B4GALT5,HEXB,B4GALT1,ST3GAL2,B4GALT4,B4GALT3,HEXA,B4GALT2 |
| 4.290e-02 | -3.15 | SCHAEFFER_PROSTATE_DEVELOPMENT_AND_CANCER_BOX4_DN | MSigDB lists | SCHAEFFER_PROSTATE_DEVELOPMENT_AND_CANCER_BOX4_DN | 32 | 9 | 17377 | 2626 |
ELOVL5,BCLAF1,IER2,GCC2,CSNK1A1,SYMPK,TMED2,EIF3A,SSR1 |
| 4.290e-02 | -3.15 | MODULE_451 | MSigDB lists | MODULE_451 | 32 | 9 | 17377 | 2626 |
PLK1,PCNA,H2AFZ,TSPYL4,MKI67,MYBL2,KPNA2,CCNB1,RPA1 |
| 4.290e-02 | -3.15 | KEGG_PROPANOATE_METABOLISM | MSigDB lists | KEGG_PROPANOATE_METABOLISM | 32 | 9 | 17377 | 2626 |
MUT,SUCLG1,LDHA,SUCLG2,ACAT1,MLYCD,ACADM,ALDH9A1,LDHB |
| 4.298e-02 | -3.15 | regulation of cell growth | biological process | GO:0001558 | 402 | 74 | 17256 | 2622 |
FGFR1OP,ADAM10,RPS6KA1,TMEM97,CSNK2A1,SMARCA4,PLXNA1,TWF2,CDK5,CDKN2C,RAB21,CDC42,ZNF639,PIN1,KIF14,DPYSL2,DNM2,ZFYVE27,CDKN1B,MTPN,EBAG9,CDKN2AIP,PSRC1,PPT1,EAF2,OGFR,PPP2CA,LIMK1,STK11,TRIM32,H3F3A,CHPT1,SMURF1,SMAD4,SLC25A33,CTDP1,DNAJB2,CIB1,IP6K2,CDK11B,HDGFL2,CRLF3,RAB11A,CDC73,MAD2L2,TFRC,RB1,MEGF8,EI24,H2AFY,BCL2,TGFB1,CYFIP1,PPP1R9B,IFRD1,RHOA,ADAM17,NET1,EXOSC9,ANAPC2,MACF1,EIF4G2,NDRG3,CDK11A,HSPA1B,GOLGA4,SERTAD2,PLAA,LTBP4,PML,DNPH1,RUFY3,CDKN2A,ADNP2 |
| 4.301e-02 | -3.15 | positive regulation of viral life cycle | biological process | GO:1903902 | 57 | 14 | 17256 | 2622 |
PPIB,STAU1,CHMP2A,SMC3,TRIM11,YTHDC2,PPIE,CHMP4B,VPS4A,CHMP2B,PABPC1,DDB1,SRPK2,RAD23A |
| 4.304e-02 | -3.15 | AAA+_ATPase | interpro domains | IPR003593 | 135 | 28 | 18492 | 2768 |
NTPCR,RFC3,ABCA3,CHTF18,ABCC10,ABCF2,TAP1,ABCB10,CDC6,ORC1,ATP5F1B,RFC2,ABCF1,WRNIP1,PSMC4,ATAD2,NVL,NSF,TAP2,ABCD1,VPS4A,RUVBL2,ABCA1,PSMC1,LONP2,RAD51D,ABCC1,ABCC5 |
| 4.304e-02 | -3.15 | inclusion body | cellular component | GO:0016234 | 80 | 18 | 18223 | 2701 |
ATXN3,CCZ1,URB2,ATXN1,RANGAP1,PSEN1,PICALM,HSPA1B,PSMC4,PRNP,RAD18,CCZ1B,FBXO7,CABIN1,NUP153,CLU,SLF1,DVL2 |
| 4.310e-02 | -3.14 | activating transcription factor binding | molecular function | GO:0033613 | 72 | 17 | 17224 | 2647 |
RB1,SMAD2,NEK6,RBL1,GABPA,SETD3,HDAC7,HIPK2,LDB1,MEF2A,MEF2D,TAF12,TAF6L,CREB1,TAF6,ATF2,MAD2L2 |
| 4.315e-02 | -3.14 | NADLER_OBESITY_DN | MSigDB lists | NADLER_OBESITY_DN | 47 | 12 | 17377 | 2626 |
CDKN2C,SDHB,DBI,ACLY,MCCC1,COX8A,UCK1,CYC1,PPA1,LDHB,BCAT2,FDFT1 |
| 4.315e-02 | -3.14 | GO_REGULATION_OF_LIPID_KINASE_ACTIVITY | MSigDB lists | GO_REGULATION_OF_LIPID_KINASE_ACTIVITY | 47 | 12 | 17377 | 2626 |
TGFB1,RB1,FGFR3,PPP2R5A,CDC42,RBL1,PIK3R2,VAV2,RAC1,PIK3IP1,LYN,CD81 |
| 4.317e-02 | -3.14 | MODULE_408 | MSigDB lists | MODULE_408 | 18 | 6 | 17377 | 2626 |
ASAH1,PSAP,GM2A,NAGLU,HEXB,GPX4 |
| 4.317e-02 | -3.14 | GO_POSITIVE_REGULATION_OF_MICROTUBULE_POLYMERIZATION | MSigDB lists | GO_POSITIVE_REGULATION_OF_MICROTUBULE_POLYMERIZATION | 18 | 6 | 17377 | 2626 |
CDKN1B,PSRC1,RGS2,TERF1,TUBGCP2,TUBGCP5 |
| 4.317e-02 | -3.14 | GO_U2_SNRNP | MSigDB lists | GO_U2_SNRNP | 18 | 6 | 17377 | 2626 |
SNRPG,SNRPD3,SF3B1,SF3A2,SNRPB,SF3B2 |
| 4.317e-02 | -3.14 | GO_RAC_PROTEIN_SIGNAL_TRANSDUCTION | MSigDB lists | GO_RAC_PROTEIN_SIGNAL_TRANSDUCTION | 18 | 6 | 17377 | 2626 |
WASF2,RHOG,CYFIP1,NCKAP1,ELMO1,ALS2 |
| 4.317e-02 | -3.14 | GARGALOVIC_RESPONSE_TO_OXIDIZED_PHOSPHOLIPIDS_YELLOW_DN | MSigDB lists | GARGALOVIC_RESPONSE_TO_OXIDIZED_PHOSPHOLIPIDS_YELLOW_DN | 18 | 6 | 17377 | 2626 |
RGL1,GEMIN4,LPCAT1,B4GALT5,PIK3R2,PML |
| 4.317e-02 | -3.14 | GO_NCRNA_3_END_PROCESSING | MSigDB lists | GO_NCRNA_3_END_PROCESSING | 18 | 6 | 17377 | 2626 |
EXOSC9,EXOSC6,EXOSC7,ERI3,FBL,RPSA |
| 4.317e-02 | -3.14 | MIZUSHIMA_AUTOPHAGOSOME_FORMATION | MSigDB lists | MIZUSHIMA_AUTOPHAGOSOME_FORMATION | 18 | 6 | 17377 | 2626 |
ATG13,ATG9A,VMP1,RB1CC1,ATG3,DCTN1 |
| 4.317e-02 | -3.14 | REACTOME_FATTY_ACYL_COA_BIOSYNTHESIS | MSigDB lists | REACTOME_FATTY_ACYL_COA_BIOSYNTHESIS | 18 | 6 | 17377 | 2626 |
ACSL5,ELOVL5,TECR,ACSL3,SLC25A1,ACLY |
| 4.317e-02 | -3.14 | GO_ATP_DEPENDENT_MICROTUBULE_MOTOR_ACTIVITY | MSigDB lists | GO_ATP_DEPENDENT_MICROTUBULE_MOTOR_ACTIVITY | 18 | 6 | 17377 | 2626 |
KIF5B,KIF3B,KIF18A,KIF18B,KIF11,KIF14 |
| 4.317e-02 | -3.14 | GO_CELLULAR_RESPONSE_TO_REACTIVE_NITROGEN_SPECIES | MSigDB lists | GO_CELLULAR_RESPONSE_TO_REACTIVE_NITROGEN_SPECIES | 18 | 6 | 17377 | 2626 |
CCNA2,MAP3K5,CDK2,STAT6,MTR,DNM2 |
| 4.317e-02 | -3.14 | BIOCARTA_NGF_PATHWAY | MSigDB lists | BIOCARTA_NGF_PATHWAY | 18 | 6 | 17377 | 2626 |
CSNK2A1,SHC1,ELK1,HRAS,RAF1,MAPK3 |
| 4.317e-02 | -3.14 | OUYANG_PROSTATE_CANCER_PROGRESSION_UP | MSigDB lists | OUYANG_PROSTATE_CANCER_PROGRESSION_UP | 18 | 6 | 17377 | 2626 |
JAK1,CDC42,STAT3,CD81,HRAS,STAT1 |
| 4.317e-02 | -3.14 | GO_MICROTUBULE_NUCLEATION | MSigDB lists | GO_MICROTUBULE_NUCLEATION | 18 | 6 | 17377 | 2626 |
NDE1,GOLGA2,CENPJ,TUBGCP2,CSNK1D,TUBGCP5 |
| 4.317e-02 | -3.14 | BIOCARTA_CALCINEURIN_PATHWAY | MSigDB lists | BIOCARTA_CALCINEURIN_PATHWAY | 18 | 6 | 17377 | 2626 |
CALM2,SP3,NFATC2,PPP3CA,NFATC3,PPP3CB |
| 4.325e-02 | -3.14 | AGGF1 (angiogenic factor with G-patch and FHA domains 1) | protein interactions | 55109 | 30 | 9 | 17029 | 2761 |
AGGF1,FOXK1,CHERP,RAE1,NABP1,XRCC3,SIKE1,IKBIP,SF3A2 |
| 4.325e-02 | -3.14 | IMP3 (IMP3, U3 small nucleolar ribonucleoprotein) | protein interactions | 55272 | 30 | 9 | 17029 | 2761 |
UTP25,NIFK,POLR2L,MPHOSPH8,RPL17,GBA,GTPBP4,UTP3,RPSA |
| 4.325e-02 | -3.14 | CNN2 (calponin 2) | protein interactions | 1265 | 30 | 9 | 17029 | 2761 |
MAT2B,TRAPPC9,PDCD10,LAGE3,ATE1,ACTB,BRCA1,CD81,FUBP1 |
| 4.325e-02 | -3.14 | Mad2l1bp (MAD2L1 binding protein) | protein interactions | 66591 | 30 | 9 | 17029 | 2761 |
AMZ2,FBXL6,CLSPN,CDCA7L,AFF1,TTC3,LRRC1,MRPL11,PACS2 |
| 4.325e-02 | -3.14 | RASSF2 (Ras association domain family member 2) | protein interactions | 9770 | 30 | 9 | 17029 | 2761 |
PPP3CA,PTEN,YWHAZ,KRAS,PPP3CB,MOB1A,COA7,YWHAH,HRAS |
| 4.325e-02 | -3.14 | ROCK2 (Rho associated coiled-coil containing protein kinase 2) | protein interactions | 9475 | 30 | 9 | 17029 | 2761 |
STAU1,CYLD,RHOA,PPP1R12A,MTA2,RACGAP1,ROCK1,LMNA,CDC5L |
| 4.325e-02 | -3.14 | PLXNA3 (plexin A3) | protein interactions | 55558 | 30 | 9 | 17029 | 2761 |
USF1,TK1,SYNCRIP,POLK,HLA-E,SMC6,CNTROB,OAZ1,PTPRK |
| 4.325e-02 | -3.14 | BICD2 (BICD cargo adaptor 2) | protein interactions | 23299 | 30 | 9 | 17029 | 2761 |
PLK1,PCM1,DCTN2,BICD2,PMF1,RAB6A,CORO1A,ZRANB1,DCTN1 |
| 4.325e-02 | -3.14 | ZMYM4 (zinc finger MYM-type containing 4) | protein interactions | 9202 | 30 | 9 | 17029 | 2761 |
CIPC,RHOC,DYNLL1,SUMO2,CUL3,CTCF,FBL,YY1AP1,SRPK2 |
| 4.325e-02 | -3.14 | TBC1D7 (TBC1 domain family member 7) | protein interactions | 51256 | 30 | 9 | 17029 | 2761 |
TSC1,MZT1,TSC2,RRAGC,SSNA1,RUVBL2,KIF2C,BECN1,APP |
| 4.325e-02 | -3.14 | TAF1C (TATA-box binding protein associated factor, RNA polymerase I subunit C) | protein interactions | 9013 | 30 | 9 | 17029 | 2761 |
UBTF,RRN3,TK1,CD3EAP,RPS14,RBM34,MECP2,H2AFX,TAF12 |
| 4.325e-02 | -3.14 | XPA (XPA, DNA damage recognition and repair factor) | protein interactions | 7507 | 30 | 9 | 17029 | 2761 |
RPA2,ERCC1,XAB2,PRKDC,MSH2,ZNF518A,DDB1,POLR2A,RPA1 |
| 4.325e-02 | -3.14 | DET1 (DET1, COP1 ubiquitin ligase partner) | protein interactions | 55070 | 30 | 9 | 17029 | 2761 |
UBE2E2,MDM2,ETS2,RBX1,DDA1,COPS7B,COPS6,RNF14,DDB1 |
| 4.325e-02 | -3.14 | KDM4B (lysine demethylase 4B) | protein interactions | 23030 | 30 | 9 | 17029 | 2761 |
CCT2,HSPA4,MED10,WDR5,KMT2C,KDM4A,CCT8,SMU1,UHRF2 |
| 4.325e-02 | -3.14 | FBXO5 (F-box protein 5) | protein interactions | 26271 | 30 | 9 | 17029 | 2761 |
PLK1,CDC16,CDC27,ANAPC2,CHMP4B,ANAPC7,BRCA1,CDC23,ANAPC4 |
| 4.325e-02 | -3.14 | GNS (glucosamine (N-acetyl)-6-sulfatase) | protein interactions | 2799 | 30 | 9 | 17029 | 2761 |
BCCIP,KIF2A,CAPN2,EIF5A,FGFR1OP,RPS6KA1,CUL1,SUMF1,CAPN1 |
| 4.325e-02 | -3.14 | ARMT1 (acidic residue methyltransferase 1) | protein interactions | 79624 | 30 | 9 | 17029 | 2761 |
ADSS,SEC31A,PPP3CA,CENPJ,UCHL5,ATIC,NKD2,NAXE,PPP3CB |
| 4.325e-02 | -3.14 | SPATA2 (spermatogenesis associated 2) | protein interactions | 9825 | 30 | 9 | 17029 | 2761 |
CYLD,GOLGA2,PFDN4,DUT,ODF2,BABAM1,SSNA1,CNTROB,APP |
| 4.325e-02 | -3.14 | CLSPN (claspin) | protein interactions | 63967 | 30 | 9 | 17029 | 2761 |
PLK1,USP7,PCNA,PMS2,TIMELESS,LTN1,USP20,BRCA1,MSH6 |
| 4.325e-02 | -3.14 | ARG1 (arginase 1) | protein interactions | 383 | 30 | 9 | 17029 | 2761 |
RPA2,CYLD,UCHL5,SUZ12,FLOT1,MCL1,MCM2,USP53,RPA1 |
| 4.334e-02 | -3.14 | GSE5503_PLN_DC_VS_SPLEEN_DC_ACTIVATED_ALLOGENIC_TCELL_UP | MSigDB lists | GSE5503_PLN_DC_VS_SPLEEN_DC_ACTIVATED_ALLOGENIC_TCELL_UP | 191 | 38 | 17377 | 2626 |
PTMS,GCLM,UNK,H2AFZ,HNRNPAB,TRIP10,PDAP1,MAGED1,CUL1,PMF1,SLC35B2,GGA2,FZD6,FBXO3,TNFAIP8,AHDC1,GNAI2,TMBIM1,TERF2,PHF10,PRIM2,KAT7,METTL5,EXOSC9,ANAPC2,EIF2A,MCFD2,CXXC4,TMEM41A,MID1IP1,KIF18A,SERTAD2,PRDX3,COX5A,SMPD4,BTF3,MZT2B,GCSH |
| 4.334e-02 | -3.14 | GSE22140_GERMFREE_VS_SPF_ARTHRITIC_MOUSE_CD4_TCELL_UP | MSigDB lists | GSE22140_GERMFREE_VS_SPF_ARTHRITIC_MOUSE_CD4_TCELL_UP | 191 | 38 | 17377 | 2626 |
TCF12,CCNC,GCLM,NUP188,HNRNPAB,ADD1,NQO1,TRIP10,MAGED1,RPL15,LETMD1,ITGB5,PDXDC1,DNAJB9,CD59,CAPN2,APLP2,VASP,SAR1A,RAB35,ORC3,CARM1,SRP72,CCT2,PPP3CA,TACC1,ELL2,WDR1,MAT2A,ISG15,PLD3,SEC23IP,GPS2,GADD45B,ERGIC3,PML,RGL1,ZC3HAV1 |
| 4.334e-02 | -3.14 | GSE22935_UNSTIM_VS_24H_MBOVIS_BCG_STIM_MACROPHAGE_DN | MSigDB lists | GSE22935_UNSTIM_VS_24H_MBOVIS_BCG_STIM_MACROPHAGE_DN | 191 | 38 | 17377 | 2626 |
KARS,C16orf87,TPX2,AGPAT3,TBC1D13,CHAC2,ETS1,LIN9,PRKD3,CBWD2,SNX18,ZNF260,RNF135,SGCB,MND1,BIRC3,CSRP1,TMEM39A,OAF,E2F3,MTMR6,FAM133B,DNAJA1,OGFR,IRF5,SERTAD2,PPP2R5A,PDLIM1,MAGT1,ACYP1,MAPK6,NFIL3,U2SURP,ITGB1,CLN3,PLOD3,FBXL3,RNF14 |
| 4.334e-02 | -3.14 | GSE41978_ID2_KO_VS_BIM_KO_KLRG1_LOW_EFFECTOR_CD8_TCELL_UP | MSigDB lists | GSE41978_ID2_KO_VS_BIM_KO_KLRG1_LOW_EFFECTOR_CD8_TCELL_UP | 191 | 38 | 17377 | 2626 |
SLC12A7,DDX58,GCLM,FAM208B,MAX,PARP12,HLA-E,TRIO,TAP1,RBM4,HLA-A,CREM,RPA2,GSTK1,CTSS,SP100,RABGAP1L,TAP2,CEP63,STAT3,TRIM14,TRAFD1,LAP3,OGFR,PSMB9,CYB5A,ISG15,DDX23,FAS,HLA-B,KIF18A,LSM6,STAT1,PML,APOL2,IFI16,ZC3HAV1,RNF114 |
| 4.334e-02 | -3.14 | GSE33424_CD161_HIGH_VS_INT_CD8_TCELL_UP | MSigDB lists | GSE33424_CD161_HIGH_VS_INT_CD8_TCELL_UP | 191 | 38 | 17377 | 2626 |
UBL3,EIF2AK4,GGA2,OAT,LYN,CHD1,ABHD14A,MAN1A1,NUDT19,HOMER1,SLC31A1,RAP1A,CLIC4,TPST1,BCAP29,AHCY,TIPARP,S100A6,DRAM2,MYO5A,POU2AF1,PSPC1,PPP1R21,KIAA0930,SLC16A7,LRRC8A,GLO1,MCL1,SERP1,HHEX,NAP1L1,RBM25,NFIL3,PRPS2,PML,ADAM9,KPNA2,GCSH |
| 4.334e-02 | -3.14 | GSE22589_HEALTHY_VS_SIV_INFECTED_DC_DN | MSigDB lists | GSE22589_HEALTHY_VS_SIV_INFECTED_DC_DN | 191 | 38 | 17377 | 2626 |
KCTD7,CORO7,ZNF768,TOR3A,TAP1,CPNE3,HEATR5B,ZNF804A,RAB8A,ZNF260,AP2B1,TAP2,MDFIC,MINPP1,PLCL2,TFG,ASB6,FAM171A1,DRAM2,SAP30,PPP3CA,TRAFD1,NEK7,PFKFB3,PCGF1,CYFIP2,MEN1,FXR1,LY6E,PHF6,OPTN,HLA-B,TWSG1,NLRC5,PML,PPP1R11,TICAM1,RNASEL |
| 4.334e-02 | -3.14 | GSE17721_CTRL_VS_LPS_6H_BMDC_DN | MSigDB lists | GSE17721_CTRL_VS_LPS_6H_BMDC_DN | 191 | 38 | 17377 | 2626 |
PRPF38B,TP53RK,DHPS,AGTRAP,LYN,REPS1,CMTM6,CHD1,MAD2L2,RRP36,PHC2,FKBP1A,HOMER1,SLC31A1,PSMA6,CBWD2,MBD2,PTPN11,MECR,H2AFY,UPF2,PPIF,TMEM39A,HARS,PPIE,ILF3,TANC1,GOSR1,PLEKHF2,ARF4,MAGED2,TRIM26,TAB2,PARG,HNRNPH3,CENPT,TSPAN5,NMD3 |
| 4.337e-02 | -3.14 | PRDM14 (PR/SET domain 14) | protein interactions | 63978 | 44 | 12 | 17029 | 2761 |
MOB4,PALB2,STRIP1,SUZ12,CDCA7L,STRN4,PSMA1,CHEK2,CBFA2T2,RCOR3,PLEKHF2,RAD51D |
| 4.337e-02 | -3.14 | PTPN23 (protein tyrosine phosphatase, non-receptor type 23) | protein interactions | 25930 | 44 | 12 | 17029 | 2761 |
KIF5B,HGS,PDCD6IP,DDX24,PRDX5,CEP55,LAGE3,KLC1,CHMP4B,ARMH3,CLTB,STAM |
| 4.337e-02 | -3.14 | MX1 (MX dynamin like GTPase 1) | protein interactions | 4599 | 44 | 12 | 17029 | 2761 |
SP100,SIAH1,CHD3,GMEB1,BRD7,ACTB,UBE2I,BLM,APP,CBX4,TUBB,ISG15 |
| 4.337e-02 | -3.14 | PRMT3 (protein arginine methyltransferase 3) | protein interactions | 10196 | 44 | 12 | 17029 | 2761 |
HSPH1,RPS2,IDE,VHL,STAT1,CNTROB,FBL,XPO7,USP11,PDCD2L,FAF1,XRCC5 |
| 4.337e-02 | -3.14 | DES (desmin) | protein interactions | 1674 | 44 | 12 | 17029 | 2761 |
RPL29,PPP1R18,SYNM,RPL17,HADHB,AURKB,BRCA1,ROCK1,SNRNP70,UBE2I,CAPN1,SPTAN1 |
| 4.337e-02 | -3.14 | ATP5PF (ATP synthase peripheral stalk subunit F6) | protein interactions | 522 | 44 | 12 | 17029 | 2761 |
CDC16,PRDX3,BANF1,MAPK6,GBA,CHCHD2,NDUFA4,ATP5F1B,ATP5F1A,ATP5MF,PARK7,TFEB |
| 4.337e-02 | -3.14 | H1F0 (H1 histone family member 0) | protein interactions | 3005 | 44 | 12 | 17029 | 2761 |
CDK5,COX15,CYLD,NOA1,SUZ12,KPNA2,PRKRA,VDAC1,CDK2,APP,IFI16,CAND1 |
| 4.337e-02 | -3.14 | L3MBTL1 (L3MBTL1, histone methyl-lysine binding protein) | protein interactions | 26013 | 44 | 12 | 17029 | 2761 |
RB1,PHF10,PCNA,FAM208B,NSMCE4A,MCM5,KMT5A,ETV6,EHMT1,MCM2,SUPT16H,CBX3 |
| 4.337e-02 | -3.14 | ILKAP (ILK associated serine/threonine phosphatase) | protein interactions | 80895 | 44 | 12 | 17029 | 2761 |
FGFR3,HGS,CSK,RPS6KA1,CERK,LTN1,PRPF4,PRPF3,CHEK2,MAPK1,SMAD4,MAPK3 |
| 4.337e-02 | -3.14 | BATF3 (basic leucine zipper ATF-like transcription factor 3) | protein interactions | 55509 | 44 | 12 | 17029 | 2761 |
USF1,ZBTB10,GOLIM4,RAD18,GOPC,TLK1,CEBPG,NFATC2IP,ATF2,STAT3,APPL1,EEF1D |
| 4.338e-02 | -3.14 | V$SREBP1_02 | MSigDB lists | V$SREBP1_02 | 84 | 19 | 17377 | 2626 |
POU2AF1,EIF5A,RHOG,ELOVL5,BAZ2A,NF1,WDR13,TAOK1,DLGAP4,NOTCH2,PATL1,KTN1,GNB2,FBRS,GNAS,DPYSL2,CORO1A,SEH1L,SMC4 |
| 4.338e-02 | -3.14 | KYNG_WERNER_SYNDROM_AND_NORMAL_AGING_UP | MSigDB lists | KYNG_WERNER_SYNDROM_AND_NORMAL_AGING_UP | 84 | 19 | 17377 | 2626 |
MBD1,TCF12,PRKAB1,ADD1,BTG2,AMD1,PRKAR1B,B4GALT1,CCNL2,ARMC8,RAB11A,PATL1,KTN1,BTBD1,SAC3D1,C14orf119,RBM17,PCNA,GCSH |
| 4.343e-02 | -3.14 | GSE12392_WT_VS_IFNAR_KO_CD8A_NEG_SPLEEN_DC_DN | MSigDB lists | GSE12392_WT_VS_IFNAR_KO_CD8A_NEG_SPLEEN_DC_DN | 168 | 34 | 17377 | 2626 |
TMBIM4,TOR1AIP1,KIAA0232,TMEM109,FBXO5,C14orf119,EEF2K,PHF14,XPA,EI24,CEP63,POLR1B,MOB1A,FBXL19,POC5,MED22,PTPN18,FOPNL,FRAT2,BOLA1,ADRB2,STX16,TMEM184C,TSC1,HHEX,TTC13,ZC3H7B,PRMT7,MRFAP1L1,CENPBD1,TRIM32,RNF139,NAA60,ANAPC4 |
| 4.343e-02 | -3.14 | GSE6269_STAPH_AUREUS_VS_STREP_PNEUMO_INF_PBMC_DN | MSigDB lists | GSE6269_STAPH_AUREUS_VS_STREP_PNEUMO_INF_PBMC_DN | 168 | 34 | 17377 | 2626 |
CASP6,TM9SF4,HNRNPUL2,TRIO,TIA1,NIT2,PAWR,AGFG1,RPAIN,ADD3,SHC1,ZKSCAN1,BDH1,EFCAB11,FOXN2,GLE1,EIF5A,SLC39A9,RPL29,PBXIP1,SELPLG,ZMYND11,LUC7L,RPS9,EPB41,KIF2A,HSPA4,PCM1,RPL32,EIF2D,IARS2,PREPL,HIPK3,N4BP2L2 |
| 4.354e-02 | -3.13 | AGO2 (argonaute 2, RISC catalytic component) | protein interactions | 27161 | 99 | 23 | 17029 | 2761 |
DHX9,CUL3,CUL1,DDX20,MCL1,BRCA1,PRKRA,RPL27A,RBM4,CAND1,CBWD2,DCP1A,CNOT6,FKBP5,TARDBP,GEMIN4,YY1,CNOT6L,IGBP1,PABPC1,EYA2,PFKP,IFI16 |
| 4.360e-02 | -3.13 | ST_PHOSPHOINOSITIDE_3_KINASE_PATHWAY | MSigDB lists | ST_PHOSPHOINOSITIDE_3_KINASE_PATHWAY | 37 | 10 | 17377 | 2626 |
PDPK1,SHC1,IARS,PTEN,RPS6KA1,AKT2,EXOSC1,YWHAZ,YWHAH,CDKN2A |
| 4.360e-02 | -3.13 | NIKOLSKY_BREAST_CANCER_1Q21_AMPLICON | MSigDB lists | NIKOLSKY_BREAST_CANCER_1Q21_AMPLICON | 37 | 10 | 17377 | 2626 |
FLAD1,MRPL9,SCAMP3,SHC1,PBXIP1,GBA,MTX1,KRTCAP2,PMVK,SLC50A1 |
| 4.360e-02 | -3.13 | TAGAACC,MIR-182 | MSigDB lists | TAGAACC,MIR-182 | 37 | 10 | 17377 | 2626 |
ACYP1,SLC16A7,NUP153,CNOT6,CADM1,HDHD2,ZNF800,CREM,SRSF10,SRSF1 |
| 4.361e-02 | -3.13 | JAEGER_METASTASIS_UP | MSigDB lists | JAEGER_METASTASIS_UP | 42 | 11 | 17377 | 2626 |
DTL,CENPF,RRM2,CDC6,KIF2C,GPI,H2AFV,NCAPG,TACC3,GINS4,SMC4 |
| 4.361e-02 | -3.13 | SHIPP_DLBCL_CURED_VS_FATAL_DN | MSigDB lists | SHIPP_DLBCL_CURED_VS_FATAL_DN | 42 | 11 | 17377 | 2626 |
GNS,TBL3,ARNTL,STAT1,LRPPRC,ASNA1,ABCD1,CITED2,CDKN2A,CAMK2G,PDCD4 |
| 4.361e-02 | -3.13 | GO_RNA_METHYLATION | MSigDB lists | GO_RNA_METHYLATION | 42 | 11 | 17377 | 2626 |
METTL1,METTL14,TRMT6,WDR4,NSUN2,METTL2A,FTSJ1,FBL,METTL3,FTSJ3,NSUN4 |
| 4.371e-02 | -3.13 | MIF4G | smart domains | SM00543 | 10 | 4 | 9493 | 1367 |
UPF2,MIF4GD,EIF4G2,PAIP1 |
| 4.371e-02 | -3.13 | HAT | smart domains | SM00386 | 10 | 4 | 9493 | 1367 |
PRPF39,PDCD11,XAB2,CRNKL1 |
| 4.371e-02 | -3.13 | Lactamase_B | smart domains | SM00849 | 10 | 4 | 9493 | 1367 |
LACTB2,HAGH,MBLAC2,HAGHL |
| 4.371e-02 | -3.13 | EMP24_GP25L | smart domains | SM01190 | 10 | 4 | 9493 | 1367 |
TMED7,TMED3,TMED10,TMED2 |
| 4.371e-02 | -3.13 | ADF | smart domains | SM00102 | 10 | 4 | 9493 | 1367 |
GMFG,TWF2,CFL1,GMFB |
| 4.372e-02 | -3.13 | haematopoietic_and_lymphoid_tissue-skin-lymphoid_neoplasm-mycosis_fungoides-Sezary_syndrome | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-skin-lymphoid_neoplasm-mycosis_fungoides-Sezary_syndrome | 53 | 13 | 17385 | 2587 |
FGFR3,RB1,NRAS,JAK1,PGGT1B,PTEN,VHL,SF3B1,STK11,KRAS,STAT3,HRAS,CDKN2A |
| 4.372e-02 | -3.13 | mycosis_fungoides-Sezary_syndrome | COSMIC cancer mutations | mycosis_fungoides-Sezary_syndrome | 53 | 13 | 17385 | 2587 |
FGFR3,RB1,NRAS,JAK1,PGGT1B,PTEN,VHL,SF3B1,STK11,KRAS,STAT3,HRAS,CDKN2A |
| 4.379e-02 | -3.13 | HSPA1L (heat shock protein family A (Hsp70) member 1 like) | protein interactions | 3305 | 141 | 31 | 17029 | 2761 |
STAU1,NPHP4,MAPRE2,SMAP1,POC1A,CUL3,CUL1,BRCA1,MCM2,METTL22,RAB11A,STOML2,CAND1,ALDH3B1,NDUFV1,SHC1,PTEN,TBC1D22A,MCM5,PIK3R2,RRBP1,UHRF2,H2AFX,DCP1A,NDUFB9,CLU,ATP5F1A,RUVBL2,COPS6,ARRB2,CDC5L |
| 4.384e-02 | -3.13 | MTRNR2L1 (MT-RNR2 like 1) | protein interactions | 100462977 | 9 | 4 | 17029 | 2761 |
MPHOSPH8,TRIM11,PPA1,PRDX1 |
| 4.384e-02 | -3.13 | RMDN1 (regulator of microtubule dynamics 1) | protein interactions | 51115 | 9 | 4 | 17029 | 2761 |
SHC1,VKORC1,CDK2,H2AFX |
| 4.384e-02 | -3.13 | SERTAD2 (SERTA domain containing 2) | protein interactions | 9792 | 9 | 4 | 17029 | 2761 |
SUPT7L,TRIM28,TFDP1,E2F1 |
| 4.384e-02 | -3.13 | PON1 (paraoxonase 1) | protein interactions | 5444 | 9 | 4 | 17029 | 2761 |
MICU2,CLU,NDUFB6,SFXN5 |
| 4.384e-02 | -3.13 | PMEPA1 (prostate transmembrane protein, androgen induced 1) | protein interactions | 56937 | 9 | 4 | 17029 | 2761 |
UBQLN4,HGS,STAM,CAND1 |
| 4.384e-02 | -3.13 | NRXN2 (neurexin 2) | protein interactions | 9379 | 9 | 4 | 17029 | 2761 |
AFDN,DDX24,MACF1,MAPK6 |
| 4.384e-02 | -3.13 | PAIP2B (poly(A) binding protein interacting protein 2B) | protein interactions | 400961 | 9 | 4 | 17029 | 2761 |
RBM3,PABPC1,LUC7L2,CIRBP |
| 4.384e-02 | -3.13 | UL122 (interacts with basal transcriptional machinery and cellular transcription factors; specific DNA-binding protein; involved in gene regulation) | protein interactions | 3077563 | 9 | 4 | 17029 | 2761 |
CSNK2A1,RB1,DYNLL1,ZMYND11 |
| 4.384e-02 | -3.13 | DGKQ (diacylglycerol kinase theta) | protein interactions | 1609 | 9 | 4 | 17029 | 2761 |
EZR,RHOA,EHD4,EIF4H |
| 4.384e-02 | -3.13 | ST5 (suppression of tumorigenicity 5) | protein interactions | 6764 | 9 | 4 | 17029 | 2761 |
MYH9,SMAD2,ANLN,MYO18A |
| 4.384e-02 | -3.13 | ARMC9 (armadillo repeat containing 9) | protein interactions | 80210 | 9 | 4 | 17029 | 2761 |
SIAH1,APP,PRPS2,NPLOC4 |
| 4.384e-02 | -3.13 | SECISBP2L (SECIS binding protein 2 like) | protein interactions | 9728 | 9 | 4 | 17029 | 2761 |
RMND5A,ARMH3,DYNLL1,PTAR1 |
| 4.384e-02 | -3.13 | PPP1R3B (protein phosphatase 1 regulatory subunit 3B) | protein interactions | 79660 | 9 | 4 | 17029 | 2761 |
NUP153,GYG1,YY1,NIPSNAP2 |
| 4.384e-02 | -3.13 | Tyw3 (tRNA-yW synthesizing protein 3 homolog (S. cerevisiae)) | protein interactions | 209584 | 9 | 4 | 17029 | 2761 |
PLD3,CSNK1D,PPP6C,NSFL1C |
| 4.384e-02 | -3.13 | AFAP1L2 (actin filament associated protein 1 like 2) | protein interactions | 84632 | 9 | 4 | 17029 | 2761 |
POT1,APP,TERF1,TERF2 |
| 4.384e-02 | -3.13 | ASPDH (aspartate dehydrogenase domain containing) | protein interactions | 554235 | 9 | 4 | 17029 | 2761 |
GALK2,CORO1A,GNPNAT1,SPATC1L |
| 4.384e-02 | -3.13 | SLF2 (SMC5-SMC6 complex localization factor 2) | protein interactions | 55719 | 9 | 4 | 17029 | 2761 |
SMC6,RAD18,SLF1,OPTN |
| 4.384e-02 | -3.13 | EGFL8 (EGF like domain multiple 8) | protein interactions | 80864 | 9 | 4 | 17029 | 2761 |
TIMM8B,LIME1,FBXO28,DNAJB9 |
| 4.384e-02 | -3.13 | MCF2L (MCF.2 cell line derived transforming sequence like) | protein interactions | 23263 | 9 | 4 | 17029 | 2761 |
RHOG,RHOA,CDC42,RAC1 |
| 4.384e-02 | -3.13 | ABTB1 (ankyrin repeat and BTB domain containing 1) | protein interactions | 80325 | 9 | 4 | 17029 | 2761 |
ZBTB21,SMAD2,EEF1D,CUL3 |
| 4.384e-02 | -3.13 | Chek1 (checkpoint kinase 1) | protein interactions | 12649 | 9 | 4 | 17029 | 2761 |
PKD2,HDGFL2,SMAD4,ACSL3 |
| 4.384e-02 | -3.13 | RAI2 (retinoic acid induced 2) | protein interactions | 10742 | 9 | 4 | 17029 | 2761 |
ATXN1,UBQLN4,APP,APPL2 |
| 4.384e-02 | -3.13 | NLRP5 (NLR family pyrin domain containing 5) | protein interactions | 126206 | 9 | 4 | 17029 | 2761 |
DECR1,LRRC1,BECN1,MATR3 |
| 4.384e-02 | -3.13 | RPL7P32 (ribosomal protein L7 pseudogene 32) | protein interactions | 100130892 | 9 | 4 | 17029 | 2761 |
CUL1,COPS6,HUWE1,CAND1 |
| 4.384e-02 | -3.13 | EVI2A (ecotropic viral integration site 2A) | protein interactions | 2123 | 9 | 4 | 17029 | 2761 |
ARRB2,GOPC,APP,RNF114 |
| 4.384e-02 | -3.13 | UNC5B (unc-5 netrin receptor B) | protein interactions | 219699 | 9 | 4 | 17029 | 2761 |
PPP2CA,CIP2A,DAPK1,TMEM216 |
| 4.384e-02 | -3.13 | PRRT2 (proline rich transmembrane protein 2) | protein interactions | 112476 | 9 | 4 | 17029 | 2761 |
TBRG4,NDUFB9,LCLAT1,NDUFS4 |
| 4.384e-02 | -3.13 | ACOT2 (acyl-CoA thioesterase 2) | protein interactions | 10965 | 9 | 4 | 17029 | 2761 |
RBM23,PEX5,WDR18,SPATA33 |
| 4.384e-02 | -3.13 | BROX (BRO1 domain and CAAX motif containing) | protein interactions | 148362 | 9 | 4 | 17029 | 2761 |
CHMP4B,TCEA1,PDCD6IP,LDHA |
| 4.384e-02 | -3.13 | EBAG9 (estrogen receptor binding site associated, antigen, 9) | protein interactions | 9166 | 9 | 4 | 17029 | 2761 |
POLR2A,EBAG9,SNAPIN,TMEM216 |
| 4.384e-02 | -3.13 | RBMS3 (RNA binding motif single stranded interacting protein 3) | protein interactions | 27303 | 9 | 4 | 17029 | 2761 |
MRPL9,MRPL40,MRPL55,MRPL19 |
| 4.384e-02 | -3.13 | ORMDL1 (ORMDL sphingolipid biosynthesis regulator 1) | protein interactions | 94101 | 9 | 4 | 17029 | 2761 |
DCUN1D5,APP,TTC33,LMNA |
| 4.384e-02 | -3.13 | TCEAL9 (transcription elongation factor A like 9) | protein interactions | 51186 | 9 | 4 | 17029 | 2761 |
RMND5A,USP11,KRBA1,KDELR1 |
| 4.384e-02 | -3.13 | Pkm (pyruvate kinase, muscle) | protein interactions | 18746 | 9 | 4 | 17029 | 2761 |
ZFYVE21,PKM,PTEN,RABGAP1L |
| 4.384e-02 | -3.13 | NYAP2 (neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adaptor 2) | protein interactions | 57624 | 9 | 4 | 17029 | 2761 |
CYFIP1,AGFG1,NCKAP1,CYFIP2 |
| 4.384e-02 | -3.13 | HOTAIR (HOX transcript antisense RNA) | protein interactions | 100124700 | 9 | 4 | 17029 | 2761 |
ATXN1,DDX5,SNUPN,AGO2 |
| 4.384e-02 | -3.13 | Elavl1 (ELAV (embryonic lethal, abnormal vision)-like 1 (Hu antigen R)) | protein interactions | 15568 | 9 | 4 | 17029 | 2761 |
UPF1,SNRNP70,CARMIL1,MRPL27 |
| 4.384e-02 | -3.13 | NPTN (neuroplastin) | protein interactions | 27020 | 9 | 4 | 17029 | 2761 |
NIT2,NDUFV2,SLC25A5,UBXN1 |
| 4.384e-02 | -3.13 | TAL2 (TAL bHLH transcription factor 2) | protein interactions | 6887 | 9 | 4 | 17029 | 2761 |
TCF12,CBFA2T2,TCF3,MAPK3 |
| 4.389e-02 | -3.13 | GSE25123_IL4_VS_IL4_AND_ROSIGLITAZONE_STIM_PPARG_KO_MACROPHAGE_DAY10_UP | MSigDB lists | GSE25123_IL4_VS_IL4_AND_ROSIGLITAZONE_STIM_PPARG_KO_MACROPHAGE_DAY10_UP | 134 | 28 | 17377 | 2626 |
NAGPA,SNX27,CLSPN,RBM42,DAP,WDR18,SNX15,UCK1,ABHD14B,PACS1,SND1,TOMM40,CHMP2B,MRPS14,PDXDC1,USP21,CD3EAP,STX18,SH3GLB2,EI24,PRC1,ACBD4,IMPDH1,TRIM32,TMEM159,NDE1,ARRB2,TACC3 |
| 4.393e-02 | -3.13 | ACACTCC,MIR-122A | MSigDB lists | ACACTCC,MIR-122A | 68 | 16 | 17377 | 2626 |
GALC,MECP2,SERP1,CD320,PAPOLA,BCAT2,CALM2,CLIC4,BRWD1,CCDC6,CS,TNPO3,ZDHHC7,FKBP5,ANKRD13C,SMARCD1 |
| 4.396e-02 | -3.12 | HSPA1A (heat shock protein family A (Hsp70) member 1A) | protein interactions | 3303 | 266 | 54 | 17029 | 2761 |
MAX,MAPRE1,ST13,NQO1,SUZ12,SUMO2,MYH9,CUL1,DNAJB1,UBQLN2,BECN1,HAUS2,TUBGCP2,RAP1A,SHC1,EIF4A3,PTEN,MCM5,AHSA1,NSFL1C,YBX1,CRY2,BCL2,PTGES3,LMAN1,CDC37,STAU1,RHOA,RBX1,VHL,CUL3,ATXN1,MCL1,NFATC2,AURKB,DNAJA1,ADRB2,MCM2,ISG15,STOML2,CAND1,HSPBP1,PEX5,HIPK2,H2AFX,STK11,YWHAZ,ATP5F1A,COPS6,MAP3K5,ECPAS,SMURF1,POT1,TUBB |
| 4.399e-02 | -3.12 | positive regulation of DNA binding | biological process | GO:0043388 | 52 | 13 | 17256 | 2622 |
TGFB1,IRF4,RB1,TXN,KAT2A,HIPK2,CEBPG,HMGB2,EDF1,SIRT2,PARK7,TRIM28,DDRGK1 |
| 4.399e-02 | -3.12 | negative regulation of phosphoprotein phosphatase activity | biological process | GO:0032515 | 52 | 13 | 17256 | 2622 |
FKBP1A,PPP1R9B,PPP1R37,PPP1R2,PPP1R8,PPME1,ENSA,PPP1R11,CRY2,CABIN1,ROCK1,GNAI2,MASTL |
| 4.399e-02 | -3.12 | intracellular protein transmembrane transport | biological process | GO:0065002 | 52 | 13 | 17256 | 2622 |
SRP72,SEC61B,TOMM20,PEX5,TIMM13,TIMM23,AKT2,TIMM29,TIMM17A,TIMM21,TOMM40,C2CD5,TIMM50 |
| 4.418e-02 | -3.12 | establishment of protein localization to mitochondrion | biological process | GO:0072655 | 73 | 17 | 17256 | 2622 |
TIMM8B,TOMM20,MTX3,TIMM21,MTX1,TOMM40,MFN2,MOAP1,TIMM13,HSPA4,TIMM23,TIMM17A,TIMM29,FBXO7,PITRM1,MTX2,TIMM50 |
| 4.418e-02 | -3.12 | regulation of phospholipid metabolic process | biological process | GO:1903725 | 73 | 17 | 17256 | 2622 |
TGFB1,ACSL3,VAV2,WDR81,ZP3,TAZ,LYN,STOML2,MTMR3,FGFR3,MTMR4,PIK3R2,PIK3IP1,SCARB1,WDR91,LPCAT1,CD81 |
| 4.420e-02 | -3.12 | positive regulation of glucose import in response to insulin stimulus | biological process | GO:2001275 | 18 | 6 | 17256 | 2622 |
RNASEL,AKT2,OSBPL8,C2CD5,PIK3R2,PTPN11 |
| 4.420e-02 | -3.12 | miRNA metabolic process | biological process | GO:0010586 | 18 | 6 | 17256 | 2622 |
KHSRP,PRKRA,DGCR8,AGO2,TUT4,DDX17 |
| 4.420e-02 | -3.12 | polarized epithelial cell differentiation | biological process | GO:0030859 | 18 | 6 | 17256 | 2622 |
EZR,DLG5,RHOA,CDC42,MYO9A,SH3BP1 |
| 4.420e-02 | -3.12 | positive regulation of lamellipodium assembly | biological process | GO:0010592 | 18 | 6 | 17256 | 2622 |
WASF2,NCKAP1,CDC42,TWF2,RAC1,DNM2 |
| 4.420e-02 | -3.12 | endoplasmic reticulum to cytosol transport | biological process | GO:1903513 | 18 | 6 | 17256 | 2622 |
DERL1,SEC61B,SYVN1,RHBDD1,NPLOC4,SEL1L |
| 4.420e-02 | -3.12 | retrograde protein transport, ER to cytosol | biological process | GO:0030970 | 18 | 6 | 17256 | 2622 |
DERL1,SEC61B,SYVN1,RHBDD1,NPLOC4,SEL1L |
| 4.420e-02 | -3.12 | regulation of exosomal secretion | biological process | GO:1903541 | 18 | 6 | 17256 | 2622 |
CHMP2A,HGS,PDCD6IP,VPS4A,STAM,RAB7A |
| 4.420e-02 | -3.12 | ganglioside metabolic process | biological process | GO:0001573 | 18 | 6 | 17256 | 2622 |
ITGB8,ST8SIA2,CLN6,GM2A,NEU1,HEXB |
| 4.420e-02 | -3.12 | regulation of protein polyubiquitination | biological process | GO:1902914 | 18 | 6 | 17256 | 2622 |
TRIP12,PLAA,GPS2,PARP10,BIRC2,XIAP |
| 4.420e-02 | -3.12 | regulation of amyloid-beta formation | biological process | GO:1902003 | 18 | 6 | 17256 | 2622 |
CLU,ROCK1,TMED10,PICALM,APP,PRNP |
| 4.420e-02 | -3.12 | protein localization to chromosome, centromeric region | biological process | GO:0071459 | 18 | 6 | 17256 | 2622 |
CTCF,RB1,AURKB,CENPT,SPDL1,MIS12 |
| 4.420e-02 | -3.12 | negative regulation of T cell receptor signaling pathway | biological process | GO:0050860 | 18 | 6 | 17256 | 2622 |
PTPN2,EZR,PAWR,DUSP3,DUSP22,PRNP |
| 4.422e-02 | -3.12 | phosphatidylglycerol metabolic process | biological process | GO:0046471 | 32 | 9 | 17256 | 2622 |
PDXP,CDS2,PGS1,MECP2,LPCAT4,HADHB,LCLAT1,LPCAT1,TAZ |
| 4.422e-02 | -3.12 | response to X-ray | biological process | GO:0010165 | 32 | 9 | 17256 | 2622 |
KARS,ERCC1,XRCC2,MSH2,DNM2,BLM,IKBIP,XRCC4,XRCC5 |
| 4.422e-02 | -3.12 | positive regulation of erythrocyte differentiation | biological process | GO:0045648 | 32 | 9 | 17256 | 2622 |
SMAP1,STAT1,HMGB2,MAPK14,STAT3,ETS1,FOXO3,ISG15,HSPA1B |
| 4.422e-02 | -3.12 | pyrimidine nucleotide biosynthetic process | biological process | GO:0006221 | 32 | 9 | 17256 | 2622 |
ERH,DUT,UCK2,CTPS1,TBPL1,UCK1,UPRT,DCTD,HDDC2 |
| 4.427e-02 | -3.12 | GSE14699_DELETIONAL_TOLERANCE_VS_ACTIVATED_CD8_TCELL_UP | MSigDB lists | GSE14699_DELETIONAL_TOLERANCE_VS_ACTIVATED_CD8_TCELL_UP | 174 | 35 | 17377 | 2626 |
SEPHS2,CLSPN,FAM129A,TCF3,HAUS4,BLM,REEP5,MXD1,MCM5,LPIN2,SEPT11,MYBL1,F2R,MTPN,MYO5A,SAP30,PLK3,DDX28,NXT1,SEC61B,ASPM,PBK,NUDT4,HTATIP2,ASF1B,MYO1F,HMGN2,AHNAK,RBM47,NEIL3,COX8A,ITGB1,FKBP5,ATF6,PFKP |
| 4.427e-02 | -3.12 | GSE1791_CTRL_VS_NEUROMEDINU_IN_T_CELL_LINE_0.8H_UP | MSigDB lists | GSE1791_CTRL_VS_NEUROMEDINU_IN_T_CELL_LINE_0.8H_UP | 174 | 35 | 17377 | 2626 |
KIAA0100,MPHOSPH8,PPP1R15B,TKT,NIT2,CUTC,EEF2K,PCYOX1L,RAB8A,INTS7,TIMM23,ETV6,TTC9C,SRI,AKR1B1,ORAI1,PRADC1,CLTB,ZC3H3,NUP85,NSUN4,SNRNP200,RBX1,EMB,ASB13,ECH1,UBTF,MRPL2,INF2,ZHX1,CHCHD1,DBI,SCARB1,PIEZO1,CCDC137 |
| 4.427e-02 | -3.12 | GSE37416_CTRL_VS_3H_F_TULARENSIS_LVS_NEUTROPHIL_DN | MSigDB lists | GSE37416_CTRL_VS_3H_F_TULARENSIS_LVS_NEUTROPHIL_DN | 174 | 35 | 17377 | 2626 |
MIF,CHMP2A,IVNS1ABP,ACTR3,ALKBH5,MYNN,NHLRC3,SLC35B2,RLF,SCYL2,LIN9,CDK5,PSMA6,BRPF3,ECD,PLK3,NXT1,ANKRD37,CCDC138,ETV3,LDHA,ARHGEF12,VDAC1,RAB1A,ARL5B,KDM3A,PAF1,ANKZF1,ETS2,MAGT1,MFAP1,PGAM1,NGLY1,ESPL1,PPP2R2D |
| 4.448e-02 | -3.11 | inflammatory_myofibroblastic_tumour | COSMIC cancer mutations | inflammatory_myofibroblastic_tumour | 23 | 7 | 17385 | 2587 |
SEC31A,KRAS,FUS,TFG,ATIC,ETV6,DCTN1 |
| 4.448e-02 | -3.11 | biliary_tract-gallbladder-other-dysplasia-carcinoma_in_situ | COSMIC cancer mutations | biliary_tract-gallbladder-other-dysplasia-carcinoma_in_situ | 23 | 7 | 17385 | 2587 |
GNAS,FGFR3,KRAS,NRAS,PTEN,EML4,HRAS |
| 4.448e-02 | -3.11 | ovary-carcinoma-mixed_carcinoma | COSMIC cancer mutations | ovary-carcinoma-mixed_carcinoma | 23 | 7 | 17385 | 2587 |
KRAS,BRCA1,DNMT3A,PTEN,SMAD4,CDKN2A,MSH2 |
| 4.448e-02 | -3.11 | biliary_tract-gallbladder-other-adenoma | COSMIC cancer mutations | biliary_tract-gallbladder-other-adenoma | 23 | 7 | 17385 | 2587 |
GNAS,FGFR3,KRAS,NRAS,PTEN,EML4,HRAS |
| 4.448e-02 | -3.11 | soft_tissue-fibrous_tissue_and_uncertain_origin-inflammatory_myofibroblastic_tumour | COSMIC cancer mutations | soft_tissue-fibrous_tissue_and_uncertain_origin-inflammatory_myofibroblastic_tumour | 23 | 7 | 17385 | 2587 |
SEC31A,KRAS,FUS,TFG,ATIC,ETV6,DCTN1 |
| 4.449e-02 | -3.11 | human chr8q24.3 | chromosome location | human chr8q24.3 | 125 | 20 | 26185 | 2809 |
TRAPPC9,TSTA3,AGO2,TIGD5,RPL8,PTP4A3,ADCK5,PLEC,LY6E,COMMD5,ZNF696,LRRC14,CYHR1,FBXL6,TONSL,CYC1,TOP1MT,PARP10,ZC3H3,EEF1D |
| 4.451e-02 | -3.11 | Vpu mediated degradation of CD4 | REACTOME pathways | R-HSA-180534 | 53 | 14 | 10287 | 1696 |
PSMD2,PSMD1,PSMA6,PSMA8,RPS27A,PSMD8,PSMD3,PSMB7,PSMA1,PSMB9,PSMD9,PSMC1,PSMB3,PSMC4 |
| 4.451e-02 | -3.11 | Autodegradation of the E3 ubiquitin ligase COP1 | REACTOME pathways | R-HSA-349425 | 53 | 14 | 10287 | 1696 |
PSMD2,PSMD1,PSMA6,PSMA8,RPS27A,PSMD8,PSMD3,PSMB7,PSMA1,PSMB9,PSMD9,PSMC1,PSMB3,PSMC4 |
| 4.462e-02 | -3.11 | mitochondrial respiratory chain complex IV | cellular component | GO:0005751 | 14 | 5 | 18223 | 2701 |
COX5A,NDUFA4,COX5B,COX4I1,COX8A |
| 4.462e-02 | -3.11 | transcription factor TFTC complex | cellular component | GO:0033276 | 14 | 5 | 18223 | 2701 |
TAF2,TAF5L,TAF12,KAT2A,TAF6 |
| 4.470e-02 | -3.11 | Zw10 (zw10 kinetochore protein) | protein interactions | 26951 | 17 | 6 | 17029 | 2761 |
RACGAP1,KNTC1,STX18,RNF5,SCFD2,C19orf25 |
| 4.470e-02 | -3.11 | ZNF92 (zinc finger protein 92) | protein interactions | 168374 | 17 | 6 | 17029 | 2761 |
CREB1,STAT6,APP,MAPK6,GPATCH4,SDC2 |
| 4.470e-02 | -3.11 | ASL (argininosuccinate lyase) | protein interactions | 435 | 17 | 6 | 17029 | 2761 |
WDYHV1,QARS,GINS4,NCDN,TUFM,SRPK2 |
| 4.470e-02 | -3.11 | SENP8 (SUMO peptidase family member, NEDD8 specific) | protein interactions | 123228 | 17 | 6 | 17029 | 2761 |
CUL1,PCNA,SMURF1,RPS14,TERF1,USP21 |
| 4.470e-02 | -3.11 | KRT75 (keratin 75) | protein interactions | 9119 | 17 | 6 | 17029 | 2761 |
CUL1,COPS6,EIF4A3,CXXC1,CAND1,CUL3 |
| 4.470e-02 | -3.11 | DNAJC30 (DnaJ heat shock protein family (Hsp40) member C30) | protein interactions | 84277 | 17 | 6 | 17029 | 2761 |
NDUFA7,EXOSC6,APP,TMED2,LMNA,NDUFS4 |
| 4.470e-02 | -3.11 | METTL2A (methyltransferase like 2A) | protein interactions | 339175 | 17 | 6 | 17029 | 2761 |
NDUFS1,PSEN1,UBR2,MAPK6,MCCC1,TOP3A |
| 4.470e-02 | -3.11 | PARP12 (poly(ADP-ribose) polymerase family member 12) | protein interactions | 64761 | 17 | 6 | 17029 | 2761 |
RPA2,KRAS,GCLM,CBX4,RNF114,RPA1 |
| 4.470e-02 | -3.11 | FAP (fibroblast activation protein alpha) | protein interactions | 2191 | 17 | 6 | 17029 | 2761 |
RBM3,PHB2,HUWE1,RBM4,CORO1C,TMEM109 |
| 4.470e-02 | -3.11 | CBR3 (carbonyl reductase 3) | protein interactions | 874 | 17 | 6 | 17029 | 2761 |
RABIF,EWSR1,CCNL2,RAB35,RPS10,MKI67 |
| 4.470e-02 | -3.11 | KLF1 (Kruppel like factor 1) | protein interactions | 10661 | 17 | 6 | 17029 | 2761 |
CSNK2A1,SMARCA4,ARID1A,PRKACA,SMARCE1,SMARCD1 |
| 4.470e-02 | -3.11 | BCL2L14 (BCL2 like 14) | protein interactions | 79370 | 17 | 6 | 17029 | 2761 |
BCL2,TRAPPC9,BCL2L1,VHL,MTA2,PPP2R2D |
| 4.470e-02 | -3.11 | SPINK7 (serine peptidase inhibitor, Kazal type 7 (putative)) | protein interactions | 84651 | 17 | 6 | 17029 | 2761 |
GID8,FTL,IDE,ARMC8,BIRC2,ZER1 |
| 4.470e-02 | -3.11 | NXN (nucleoredoxin) | protein interactions | 64359 | 17 | 6 | 17029 | 2761 |
PPP2CA,ARRDC1,CRY2,NCKAP1,GORASP1,ABI1 |
| 4.470e-02 | -3.11 | GFM2 (G elongation factor mitochondrial 2) | protein interactions | 84340 | 17 | 6 | 17029 | 2761 |
TRIM41,MRPL2,RPL17,NDUFS7,MRPL12,TUFM |
| 4.470e-02 | -3.11 | RBMY1F (RNA binding motif protein, Y-linked, family 1, member F) | protein interactions | 159163 | 17 | 6 | 17029 | 2761 |
YTHDC1,AEN,RBM3,CLK3,RBMX,CIRBP |
| 4.470e-02 | -3.11 | Aurkb (aurora kinase B) | protein interactions | 20877 | 17 | 6 | 17029 | 2761 |
UBE2D3,ZFYVE21,AURKB,KAT7,AKAP8,CDCA8 |
| 4.470e-02 | -3.11 | MBD5 (methyl-CpG binding domain protein 5) | protein interactions | 55777 | 17 | 6 | 17029 | 2761 |
EIF2S2,RHOA,HDGFL2,PMVK,ASXL2,NAA50 |
| 4.470e-02 | -3.11 | FAM114A1 (family with sequence similarity 114 member A1) | protein interactions | 92689 | 17 | 6 | 17029 | 2761 |
AKT1S1,HSPA4,AGTRAP,TARS,RAB2B,FAF1 |
| 4.470e-02 | -3.11 | HOXB7 (homeobox B7) | protein interactions | 3217 | 17 | 6 | 17029 | 2761 |
CSNK2A1,IMPDH1,CLK3,PRKDC,APP,XRCC5 |
| 4.470e-02 | -3.11 | GORAB (golgin, RAB6 interacting) | protein interactions | 92344 | 17 | 6 | 17029 | 2761 |
CRKL,FARSA,MDM2,APP,SCYL1,TMEM216 |
| 4.470e-02 | -3.11 | ARX (aristaless related homeobox) | protein interactions | 170302 | 17 | 6 | 17029 | 2761 |
GTSE1,CYFIP1,CLTB,SEC16A,RBM4,TACC3 |
| 4.470e-02 | -3.11 | SBSN (suprabasin) | protein interactions | 374897 | 17 | 6 | 17029 | 2761 |
VAV1,GMCL1,CYLD,MCM2,POLK,MCM5 |
| 4.470e-02 | -3.11 | Mzt2 (mitotic spindle organizing protein 2) | protein interactions | 72083 | 17 | 6 | 17029 | 2761 |
MZT2A,MZT1,MZT2B,DCAF8,TUBGCP2,TUBGCP5 |
| 4.470e-02 | -3.11 | GFM1 (G elongation factor mitochondrial 1) | protein interactions | 85476 | 17 | 6 | 17029 | 2761 |
BOLA1,ADRB2,NDUFS7,MRPL12,TUFM,RPL23A |
| 4.470e-02 | -3.11 | NECAP1 (NECAP endocytosis associated 1) | protein interactions | 25977 | 17 | 6 | 17029 | 2761 |
GTSE1,KHDC4,PITPNA,APP,UFC1,NECAP2 |
| 4.470e-02 | -3.11 | NGB (neuroglobin) | protein interactions | 58157 | 17 | 6 | 17029 | 2761 |
TRIM32,CCNB1,PTEN,GNAI2,L3MBTL3,FLOT1 |
| 4.470e-02 | -3.11 | CORO6 (coronin 6) | protein interactions | 84940 | 17 | 6 | 17029 | 2761 |
CORO1A,POC1A,CORO1C,TACC3,TIGD5,PCGF6 |
| 4.470e-02 | -3.11 | MYPN (myopalladin) | protein interactions | 84665 | 17 | 6 | 17029 | 2761 |
GTSE1,DHX8,CAPZA2,MCM2,ANKRD23,MTA2 |
| 4.470e-02 | -3.11 | ARL6IP6 (ADP ribosylation factor like GTPase 6 interacting protein 6) | protein interactions | 151188 | 17 | 6 | 17029 | 2761 |
CHMP4A,DUSP3,CBFB,PMVK,APP,NAA50 |
| 4.470e-02 | -3.11 | MYOCD (myocardin) | protein interactions | 93649 | 17 | 6 | 17029 | 2761 |
SMARCA4,HSPA4,SMAD2,ARRB2,KDM3A,GOPC |
| 4.470e-02 | -3.11 | Numb (NUMB endocytic adaptor protein) | protein interactions | 18222 | 17 | 6 | 17029 | 2761 |
AP2B1,BCLAF1,AP1B1,FXR1,AP2S1,REPS1 |
| 4.470e-02 | -3.11 | PAK3 (p21 (RAC1) activated kinase 3) | protein interactions | 5063 | 17 | 6 | 17029 | 2761 |
CDC42,NCK1,MAPK14,GIT2,RAF1,RAC1 |
| 4.470e-02 | -3.11 | DCXR (dicarbonyl and L-xylulose reductase) | protein interactions | 51181 | 17 | 6 | 17029 | 2761 |
CAB39,GPI,DMWD,ASB6,APP,DEF6 |
| 4.470e-02 | -3.11 | TMEM14B (transmembrane protein 14B) | protein interactions | 81853 | 17 | 6 | 17029 | 2761 |
SRSF3,SRSF5,AGTRAP,SDHA,PSMD3,LMNA |
| 4.470e-02 | -3.11 | KCNJ5 (potassium voltage-gated channel subfamily J member 5) | protein interactions | 3762 | 17 | 6 | 17029 | 2761 |
MTMR6,PKP4,ADRB2,ERI3,WDR45B,GNB2 |
| 4.470e-02 | -3.11 | NAALADL2 (N-acetylated alpha-linked acidic dipeptidase like 2) | protein interactions | 254827 | 17 | 6 | 17029 | 2761 |
SCARB2,CELSR2,SCAP,APP,CUL3,KCTD17 |
| 4.474e-02 | -3.11 | nucleoside biosynthetic process | biological process | GO:0009163 | 47 | 12 | 17256 | 2622 |
ADA2,TK1,GUK1,DCK,AMD1,UCK2,CTPS1,UPRT,IMPDH1,UCK1,DHFR2,PDCL3 |
| 4.474e-02 | -3.11 | PBRM1 (polybromo 1) | protein interactions | 55193 | 49 | 13 | 17029 | 2761 |
ARID2,VHL,UHRF2,BCL7C,BRD7,SMARCA4,ARID1A,PBRM1,MAML1,SMARCE1,APP,IFI16,SMARCD1 |
| 4.474e-02 | -3.11 | NFKBIB (NFKB inhibitor beta) | protein interactions | 4793 | 49 | 13 | 17029 | 2761 |
BAK1,NCOR2,POLR2L,CD3EAP,LRPPRC,BRAP,CUL1,CSNK2A1,PDCD2,KPNA2,POLR1B,APP,GIT2 |
| 4.474e-02 | -3.11 | SPI1 (Spi-1 proto-oncogene) | protein interactions | 6688 | 49 | 13 | 17029 | 2761 |
VAV1,IRF4,RB1,DNMT3A,ETS2,MECP2,PML,CSNK2A1,FUS,ETS1,TMX1,CREM,SSRP1 |
| 4.474e-02 | -3.11 | PIBF1 (progesterone immunomodulatory binding factor 1) | protein interactions | 10464 | 49 | 13 | 17029 | 2761 |
EXOC3,SNX27,FGFR1OP,MAPRE1,PCM1,CCDC14,PPP1R21,ODF2,CEP63,SASS6,BORA,APP,POC5 |
| 4.474e-02 | -3.11 | AMPH (amphiphysin) | protein interactions | 273 | 49 | 13 | 17029 | 2761 |
CDK5,SYNM,REPS2,DNAAF2,MAPK6,DNM2,AP2B1,CABIN1,AP1B1,TERF1,AP2S1,REPS1,SH3GLB1 |
| 4.474e-02 | -3.11 | DSN1 (DSN1 homolog, MIS12 kinetochore complex component) | protein interactions | 79980 | 49 | 13 | 17029 | 2761 |
CTDP1,PCNA,COPA,DSN1,PML,MYH9,NUF2,ICE2,TTC3,PMF1,APP,MIS12,CBX3 |
| 4.474e-02 | -3.11 | WDR18 (WD repeat domain 18) | protein interactions | 57418 | 49 | 13 | 17029 | 2761 |
TK1,EIF4A3,NOA1,TEX10,SF3B6,USP42,CUL3,KIF2C,DUSP22,IFI16,LMNA,CDC5L,SRSF1 |
| 4.474e-02 | -3.11 | NCAPH (non-SMC condensin I complex subunit H) | protein interactions | 23397 | 49 | 13 | 17029 | 2761 |
H2AFZ,CCP110,POC1A,SLC38A10,RP2,AURKB,PLEC,SMC2,ARPC1A,NCAPG,SMC4,RBM15B,CDC5L |
| 4.474e-02 | -3.11 | RFWD3 (ring finger and WD repeat domain 3) | protein interactions | 55159 | 49 | 13 | 17029 | 2761 |
UBE2D3,RPA2,LYAR,CCT2,MBIP,MDM2,DNAJB2,GLG1,ATP6V0D1,CCT8,PIP4K2A,APP,RPA1 |
| 4.477e-02 | -3.11 | Fc gamma R-mediated phagocytosis | KEGG pathways | hsa04666 | 90 | 21 | 7161 | 1149 |
WASF2,RAF1,AKT2,RAC1,VAV2,LYN,ARPC1A,MAPK3,PIP5K1C,VAV1,CRKL,ASAP2,WAS,VASP,CDC42,ARPC5,LIMK1,PIK3R2,DNM2,MAPK1,CFL1 |
| 4.477e-02 | -3.11 | Fc gamma R-mediated phagocytosis | KEGG pathways | ko04666 | 90 | 21 | 7161 | 1149 |
WASF2,RAF1,AKT2,RAC1,VAV2,LYN,ARPC1A,MAPK3,PIP5K1C,VAV1,CRKL,ASAP2,WAS,VASP,CDC42,ARPC5,LIMK1,PIK3R2,DNM2,MAPK1,CFL1 |
| 4.489e-02 | -3.10 | APOA1 (apolipoprotein A1) | protein interactions | 335 | 89 | 21 | 17029 | 2761 |
SNX27,TOMM20,AKT2,BRAP,MAP7D1,ATP5F1B,VKORC1,SAFB2,APP,MIS12,CTSL,TNS3,UCHL5,MAPK6,NAXE,DDX31,SCARB1,CLU,ZNRD1,ABCA1,APOL1 |
| 4.489e-02 | -3.10 | Tmod3 (tropomodulin 3) | protein interactions | 50875 | 89 | 21 | 17029 | 2761 |
ADD1,PPP1R12A,LUZP1,MTERF1,WDR1,FLOT1,CAPZA2,GNB2,CD59,INF2,UBXN2A,ADD3,CDC42,CORO1C,CAPZA1,CHMP4B,ACTB,CLTB,CFL1,MYO5A,SPTAN1 |
| 4.491e-02 | -3.10 | LIU_CMYB_TARGETS_UP | MSigDB lists | LIU_CMYB_TARGETS_UP | 157 | 32 | 17377 | 2626 |
NQO1,CASP6,RAB11B,GMCL1,OAT,MAP1LC3B,DNAJB9,SAC3D1,ZER1,PDK2,ADD3,SLC1A4,WDR44,CITED2,TIPARP,PACS2,IMPA2,SAP30,NAGPA,EMP3,RRM2,ESYT1,MARK2,AKAP1,MAPK3,RBM47,ANP32E,NCOA1,ARRB2,TOB1,PDCD4,HIGD2A |
| 4.503e-02 | -3.10 | response to monoamine | biological process | GO:0071867 | 37 | 10 | 17256 | 2622 |
GABPA,DNM2,SIRT2,KCNQ1,PRKACA,MAPK1,APP,RNLS,HDAC2,MAPK3 |
| 4.503e-02 | -3.10 | response to catecholamine | biological process | GO:0071869 | 37 | 10 | 17256 | 2622 |
GABPA,DNM2,SIRT2,KCNQ1,PRKACA,MAPK1,APP,RNLS,HDAC2,MAPK3 |
| 4.503e-02 | -3.10 | cellular metabolic compound salvage | biological process | GO:0043094 | 37 | 10 | 17256 | 2622 |
AMPD2,ADA2,TK1,DCK,MRI1,UCK2,UCK1,UPRT,PDXK,HDDC2 |
| 4.503e-02 | -3.10 | regulation of defense response to virus by host | biological process | GO:0050691 | 37 | 10 | 17256 | 2622 |
DDX58,TNFAIP3,CGAS,DHX9,PQBP1,STAT1,MAVS,IRF3,IL12RB1,EIF2AK4 |
| 4.503e-02 | -3.10 | virion assembly | biological process | GO:0019068 | 37 | 10 | 17256 | 2622 |
CHMP2A,CHMP4A,PDCD6IP,RPS27A,CHMP4B,VPS4A,CHMP2B,RAB1A,LRSAM1,CHMP7 |
| 4.504e-02 | -3.10 | ZnF_C2HC | smart domains | SM00343 | 19 | 6 | 9493 | 1367 |
ZCCHC9,CPSF4,ZCCHC8,RBM4,TUT4,ZCCHC2 |
| 4.504e-02 | -3.10 | GSE21379_TFH_VS_NON_TFH_CD4_TCELL_UP | MSigDB lists | GSE21379_TFH_VS_NON_TFH_CD4_TCELL_UP | 180 | 36 | 17377 | 2626 |
MOB4,NIPAL3,TIMP2,CYLD,BAZ2A,IVNS1ABP,USP42,CAMSAP1,CIRBP,CTCF,ARGLU1,NOTCH2,EAF2,TTC33,ZFR,PAIP2,CDKN2C,HLA-B,ZKSCAN1,WDR44,MAFK,SETD3,ZCCHC2,TPST1,UPF2,RNF19A,DMWD,PTPDC1,TP53BP2,TFDP2,ST8SIA2,RNF14,TOB1,FGFR1OP2,SVIP,DDX42 |
| 4.504e-02 | -3.10 | GSE1460_INTRATHYMIC_T_PROGENITOR_VS_NAIVE_CD4_TCELL_ADULT_BLOOD_DN | MSigDB lists | GSE1460_INTRATHYMIC_T_PROGENITOR_VS_NAIVE_CD4_TCELL_ADULT_BLOOD_DN | 180 | 36 | 17377 | 2626 |
KCTD7,CYTIP,IER2,CYLD,SH2D3A,MPHOSPH8,TOR1AIP1,HABP4,AP3M2,CIB1,BTN3A1,TGOLN2,CRLF3,APH1B,FBXO3,TET3,LPIN2,CITED2,PLCL2,FAM171A1,NCOA2,TMBIM1,S100A6,KCNAB2,VOPP1,FTL,PIP4K2C,PRMT2,CBFA2T2,STX16,SERP1,PPP2R5A,JAK1,GOLGA8A,PDXK,IGBP1 |
| 4.504e-02 | -3.10 | GSE16385_MONOCYTE_VS_12H_ROSIGLITAZONE_IFNG_TNF_TREATED_MACROPHAGE_UP | MSigDB lists | GSE16385_MONOCYTE_VS_12H_ROSIGLITAZONE_IFNG_TNF_TREATED_MACROPHAGE_UP | 180 | 36 | 17377 | 2626 |
TMUB1,KDM4A,TRAK1,SLC39A13,KCTD17,KLC1,COX4I1,AKT1S1,PMVK,TCF19,PABPC4,LMNA,MAT2B,CDKN2C,ERI3,ORC3,ASB6,GM2A,NEK7,USP10,MRPS10,AURKB,BUD13,TARS,PSMB3,PWWP2B,CDC27,CCDC86,WNT5B,NEIL3,PQBP1,CANT1,FN3KRP,MBD6,AKNA,FAF1 |
| 4.504e-02 | -3.10 | GSE32986_CURDLAN_LOWDOSE_VS_GMCSF_AND_CURDLAN_LOWDOSE_STIM_DC_UP | MSigDB lists | GSE32986_CURDLAN_LOWDOSE_VS_GMCSF_AND_CURDLAN_LOWDOSE_STIM_DC_UP | 180 | 36 | 17377 | 2626 |
NAT9,GLT8D1,PKP4,FAM129A,SIRT2,TMEM165,SDHA,COPG2,BCAP31,TUBGCP2,TMCC3,STARD9,ITGB8,KIF13B,CDKN1B,DNMT1,ATP6V0D1,TMEM14C,NCOA2,PACS2,GPX4,GABPA,ASPM,HTATIP2,PFKFB3,RIT1,CCNF,CYFIP2,MYO1F,HAUS8,PRIM1,TMEM127,RBL1,STK38,EXOC4,PDXK |
| 4.511e-02 | -3.10 | pancreas-other-dysplasia-in_situ_neoplasm | COSMIC cancer mutations | pancreas-other-dysplasia-in_situ_neoplasm | 48 | 12 | 17385 | 2587 |
GNAS,FGFR3,RB1,NRAS,PTEN,VHL,PTPN11,STK11,KRAS,SMAD4,HRAS,CDKN2A |
| 4.511e-02 | -3.10 | central_nervous_system-temporal_lobe-glioma-astrocytoma_Grade_IV | COSMIC cancer mutations | central_nervous_system-temporal_lobe-glioma-astrocytoma_Grade_IV | 48 | 12 | 17385 | 2587 |
ENPP4,AHNAK,NF1,PTEN,PSPC1,MSH2,KRAS,H3F3A,ZNF407,DCAF5,CDKN2A,MSH6 |
| 4.511e-02 | -3.10 | central_nervous_system-frontal_lobe-glioma-astrocytoma_Grade_IV | COSMIC cancer mutations | central_nervous_system-frontal_lobe-glioma-astrocytoma_Grade_IV | 48 | 12 | 17385 | 2587 |
RAB8A,NF1,PTEN,MSH2,CDKN1B,KRAS,ESYT1,TCOF1,H3F3A,MRPS14,MSH6,CDKN2A |
| 4.511e-02 | -3.10 | dysplasia-in_situ_neoplasm | COSMIC cancer mutations | dysplasia-in_situ_neoplasm | 48 | 12 | 17385 | 2587 |
GNAS,FGFR3,RB1,NRAS,PTEN,VHL,PTPN11,STK11,KRAS,SMAD4,HRAS,CDKN2A |
| 4.513e-02 | -3.10 | base-excision repair | biological process | GO:0006284 | 42 | 11 | 17256 | 2622 |
RPA2,POLE,HUWE1,NEIL3,XPA,MPG,OGG1,NEIL2,MBD4,POLQ,RPA1 |
| 4.513e-02 | -3.10 | thioester biosynthetic process | biological process | GO:0035384 | 42 | 11 | 17256 | 2622 |
ACSL5,ELOVL5,PPT1,ACSL3,ACLY,MLYCD,ACAT1,TECR,PDHX,MPC1,SLC25A1 |
| 4.513e-02 | -3.10 | substantia nigra development | biological process | GO:0021762 | 42 | 11 | 17256 | 2622 |
CALM2,RHOA,CDC42,CCDC14,DYNLL1,ACTB,GLUD1,SIRT2,SEC16A,YWHAH,ATP5PF |
| 4.513e-02 | -3.10 | acyl-CoA biosynthetic process | biological process | GO:0071616 | 42 | 11 | 17256 | 2622 |
ACSL5,ELOVL5,PPT1,ACSL3,ACLY,MLYCD,ACAT1,TECR,PDHX,MPC1,SLC25A1 |
| 4.514e-02 | -3.10 | MORF_BRCA1 | MSigDB lists | MORF_BRCA1 | 250 | 48 | 17377 | 2626 |
RECQL,ATXN3,TMEM184B,POLR2K,NF1,SLC2A1,HABP4,KLHL18,ABCB10,NKRF,PRKACA,CDC73,FANCI,KRR1,RAP1A,MDM2,TBC1D22A,ZNF200,GTSE1,ATP6V0A2,ZBTB22,TAF5L,GLE1,CPSF4,ATF2,CAMK2G,PHF10,PRIM2,RB1CC1,SIGMAR1,ZNF500,ZNF202,MKI67,UBE4B,BRCA1,CCNF,ERC1,NMT2,TAF2,BRWD1,LTBP4,TTLL4,TPP2,PIAS2,USP20,TFDP2,PPP5C,RAD51D |
| 4.516e-02 | -3.10 | TCATCTC,MIR-143 | MSigDB lists | TCATCTC,MIR-143 | 140 | 29 | 17377 | 2626 |
RMND5A,SRSF11,PHF20L1,DNMT3A,SIGMAR1,TSC22D3,RAB7A,MOGS,AGPAT1,ENSA,KRAS,BRCA1,GALNT7,CBFB,PHF6,GNS,ADD3,MEX3C,BRD2,ETV6,TARDBP,SCAMP4,AHCYL1,CNNM3,ASB6,CSNK1G3,SMNDC1,PRPF19,EGLN1 |
| 4.522e-02 | -3.10 | CRK (CRK proto-oncogene, adaptor protein) | protein interactions | 1398 | 272 | 55 | 17029 | 2761 |
SRM,PPP1R12A,CAST,CHTF18,VAV2,AGO2,PTTG1,HABP4,STRN4,DHX9,KCTD17,NANS,INO80E,SPR,PRKACA,REPS1,LMNA,CRKL,PHC2,TERF2IP,ABL2,VAV1,LHX8,SHC1,CCP110,KLHL20,SH3BP1,HUWE1,ATIC,PIK3R2,RTCB,PTPN11,SOCS6,AP2B1,MRPL48,RYBP,ARHGAP17,NCK1,ATXN1,ELK1,MPG,ANLN,RAB2B,HSPA1B,ANKZF1,INF2,HSPBP1,CORO1C,ODF2,DDX5,ACTB,PSMC1,POT1,TUBB,FUBP1 |
| 4.523e-02 | -3.10 | Testicular germ cell tumor(PMID:19483681) | GWAS genes | Testicular germ cell tumor(PMID:19483681) | 3 | 2 | 2388 | 307 |
BAK1,UCK2 |
| 4.523e-02 | -3.10 | Schizophrenia(PMID:20185149) | GWAS genes | Schizophrenia(PMID:20185149) | 3 | 2 | 2388 | 307 |
PLAA,ANK3 |
| 4.523e-02 | -3.10 | Amyloid A Levels(PMID:21124955) | GWAS genes | Amyloid A Levels(PMID:21124955) | 3 | 2 | 2388 | 307 |
HPS5,LDHA |
| 4.523e-02 | -3.10 | Eye color traits(PMID:20463881) | GWAS genes | Eye color traits(PMID:20463881) | 3 | 2 | 2388 | 307 |
TTC3,NPLOC4 |
| 4.523e-02 | -3.10 | Inflammatory bowel disease (early onset)(PMID:19915574) | GWAS genes | Inflammatory bowel disease (early onset)(PMID:19915574) | 3 | 2 | 2388 | 307 |
ZMIZ1,ATXN2L |
| 4.528e-02 | -3.09 | soft_tissue-small_round_cell_tumour | COSMIC cancer mutations | soft_tissue-small_round_cell_tumour | 14 | 5 | 17385 | 2587 |
FGFR3,KRAS,FUS,EWSR1,CIC |
| 4.528e-02 | -3.09 | small_round_cell_tumour | COSMIC cancer mutations | small_round_cell_tumour | 14 | 5 | 17385 | 2587 |
FGFR3,KRAS,FUS,EWSR1,CIC |
| 4.528e-02 | -3.09 | large_intestine-rectum-adenoma-tubulovillous | COSMIC cancer mutations | large_intestine-rectum-adenoma-tubulovillous | 14 | 5 | 17385 | 2587 |
KRAS,STK11,NRAS,PTEN,SMAD4 |
| 4.528e-02 | -3.09 | conventional | COSMIC cancer mutations | conventional | 14 | 5 | 17385 | 2587 |
KRAS,EWSR1,NRAS,HRAS,CDKN2A |
| 4.528e-02 | -3.09 | in_situ_neoplasm | COSMIC cancer mutations | in_situ_neoplasm | 14 | 5 | 17385 | 2587 |
FGFR3,NRAS,PTEN,HRAS,CDKN2A |
| 4.528e-02 | -3.09 | large_intestine-rectum-adenoma-tubular | COSMIC cancer mutations | large_intestine-rectum-adenoma-tubular | 14 | 5 | 17385 | 2587 |
KRAS,STK11,NRAS,PTEN,SMAD4 |
| 4.528e-02 | -3.09 | soft_tissue-blood_vessel-haemangioma-epithelioid | COSMIC cancer mutations | soft_tissue-blood_vessel-haemangioma-epithelioid | 14 | 5 | 17385 | 2587 |
TSC1,KRAS,NRAS,TSC2,PTEN |
| 4.535e-02 | -3.09 | Mitotic Spindle Checkpoint | REACTOME pathways | R-HSA-69618 | 21 | 7 | 10287 | 1696 |
ANAPC2,ANAPC7,CDC16,CDC23,CDC27,UBE2C,ANAPC4 |
| 4.535e-02 | -3.09 | Signal transduction by L1 | REACTOME pathways | R-HSA-445144 | 21 | 7 | 10287 | 1696 |
CSNK2A1,MAPK1,MAP2K2,VAV2,RAC1,MAPK3,ITGB1 |
| 4.539e-02 | -3.09 | ARM | smart domains | SM00185 | 39 | 10 | 9493 | 1367 |
PKP4,USO1,KPNA4,KPNA1,AP2B1,KIFAP3,KPNA2,AP1B1,ARMC8,ZER1 |
| 4.542e-02 | -3.09 | human chr10p13 | chromosome location | human chr10p13 | 38 | 8 | 26185 | 2809 |
MCM10,DCLRE1C,SUV39H2,FAM171A1,PTER,NMT2,PRPF18,OPTN |
| 4.542e-02 | -3.09 | human chr3p21.2 | chromosome location | human chr3p21.2 | 38 | 8 | 26185 | 2809 |
RPL29,WDR82,ABHD14B,TWF2,MAPKAPK3,POC1A,ABHD14A,RBM15B |
| 4.545e-02 | -3.09 | Chmp4b (charged multivesicular body protein 4B) | protein interactions | 75608 | 84 | 20 | 17029 | 2761 |
YTHDC1,CHMP2A,PDCD6IP,PHB2,ERLIN1,FLOT1,RACGAP1,EFL1,ATP6V1B2,CHMP2B,KTN1,TFRC,XPR1,CHAF1A,STOML2,PDCD6,CHMP4A,UAP1,MVP,ATP6V0D1 |
| 4.545e-02 | -3.09 | TRIM32 (tripartite motif containing 32) | protein interactions | 22954 | 84 | 20 | 17029 | 2761 |
DDX58,UBE2D3,EXOC3,UBQLN4,UBE2E2,BIRC3,XIAP,TKT,CUL3,ATXN1,UBE2V1,MCM2,BIRC2,HSPA4,SEC23IP,GLIS2,PTPN11,YWHAZ,TRIM32,YWHAH |
| 4.548e-02 | -3.09 | fibroblast growth factor receptor signaling pathway | biological process | GO:0008543 | 84 | 19 | 17256 | 2622 |
SHOC2,RAB14,POLR2I,POLR2G,POLR2L,POLR2K,POLR2D,HNRNPF,TIA1,SHCBP1,POLR2A,MAPK3,GTF2F1,FGFR3,POLR2J,RPS27A,PTPN11,MAPK1,HNRNPM |
| 4.548e-02 | -3.09 | DNA modification | biological process | GO:0006304 | 84 | 19 | 17256 | 2622 |
EXOSC6,HEMK1,DNMT3A,BAZ2A,KMT2E,MTA2,EHMT1,ALKBH5,KDM1B,MPG,TRIM28,NEIL2,MBD4,TET3,GNAS,PRMT7,BEND3,OGG1,DNMT1 |
| 4.549e-02 | -3.09 | protein kinase regulator activity | molecular function | GO:0019887 | 200 | 40 | 17224 | 2647 |
CCNC,FGFR1OP,GMFG,DBF4,CIB1,CCNL2,CCNB1,DAZAP2,CALM2,CDKN2C,CCNK,SOCS6,DUS2,H2AFY,CDKN1B,ATG13,ABI1,MLST8,SOCS5,CHP1,CDC37,TGFB1,NCK1,TAOK1,GMFB,PRKAR1B,ELP4,MARK2,MAP2K2,SOCS7,SH3BP5,MBIP,QARS,SOCS4,RPLP1,CAB39,STK11,FAF1,CDKN2A,ALS2 |
| 4.558e-02 | -3.09 | Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants | REACTOME pathways | R-HSA-2894862 | 58 | 15 | 10287 | 1696 |
MIB2,CCNC,NCOR2,ADAM17,KAT2A,ADAM10,RBX1,APH1A,RPS27A,HDAC7,CUL1,RBPJ,MAML1,APH1B,HDAC2 |
| 4.558e-02 | -3.09 | Signaling by NOTCH1 in Cancer | REACTOME pathways | R-HSA-2644603 | 58 | 15 | 10287 | 1696 |
MIB2,CCNC,NCOR2,ADAM17,KAT2A,ADAM10,RBX1,APH1A,RPS27A,HDAC7,CUL1,RBPJ,MAML1,APH1B,HDAC2 |
| 4.558e-02 | -3.09 | Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer | REACTOME pathways | R-HSA-2894858 | 58 | 15 | 10287 | 1696 |
MIB2,CCNC,NCOR2,ADAM17,KAT2A,ADAM10,RBX1,APH1A,RPS27A,HDAC7,CUL1,RBPJ,MAML1,APH1B,HDAC2 |
| 4.558e-02 | -3.09 | Constitutive Signaling by NOTCH1 PEST Domain Mutants | REACTOME pathways | R-HSA-2644606 | 58 | 15 | 10287 | 1696 |
MIB2,CCNC,NCOR2,ADAM17,KAT2A,ADAM10,RBX1,APH1A,RPS27A,HDAC7,CUL1,RBPJ,MAML1,APH1B,HDAC2 |
| 4.558e-02 | -3.09 | Signaling by NOTCH1 PEST Domain Mutants in Cancer | REACTOME pathways | R-HSA-2644602 | 58 | 15 | 10287 | 1696 |
MIB2,CCNC,NCOR2,ADAM17,KAT2A,ADAM10,RBX1,APH1A,RPS27A,HDAC7,CUL1,RBPJ,MAML1,APH1B,HDAC2 |
| 4.558e-02 | -3.09 | mitochondrial small ribosomal subunit | cellular component | GO:0005763 | 28 | 8 | 18223 | 2701 |
MRPS10,DAP3,MRPL42,MRPS2,MRPS15,MRPS14,MRPS27,MRPS26 |
| 4.558e-02 | -3.09 | organellar small ribosomal subunit | cellular component | GO:0000314 | 28 | 8 | 18223 | 2701 |
MRPS10,DAP3,MRPL42,MRPS2,MRPS15,MRPS14,MRPS27,MRPS26 |
| 4.559e-02 | -3.09 | REACTOME_GLUCOSE_METABOLISM | MSigDB lists | REACTOME_GLUCOSE_METABOLISM | 63 | 15 | 17377 | 2626 |
CALM2,PPP2CA,UGP2,GOT2,MDH2,SLC25A12,PFKFB3,MDH1,GPI,GYG1,PRKACA,PGAM1,PHKG2,PFKP,SLC25A1 |
| 4.559e-02 | -3.09 | GO_PROTEIN_LOCALIZATION_TO_MITOCHONDRION | MSigDB lists | GO_PROTEIN_LOCALIZATION_TO_MITOCHONDRION | 63 | 15 | 17377 | 2626 |
MOAP1,TIMM8B,TOMM20,HSPA4,TIMM13,MTX3,TIMM23,TIMM17A,FBXO7,MTX1,DNAJA1,TOMM40,MTX2,MFN2,TIMM50 |
| 4.559e-02 | -3.09 | HESS_TARGETS_OF_HOXA9_AND_MEIS1_UP | MSigDB lists | HESS_TARGETS_OF_HOXA9_AND_MEIS1_UP | 63 | 15 | 17377 | 2626 |
TFAP4,PPAN,IMMT,IDE,DUT,SLC26A6,MYBL2,MSH2,RRM1,BCL7C,RUVBL2,RRS1,ICAM2,ODC1,HDAC2 |
| 4.559e-02 | -3.09 | BYSTROEM_CORRELATED_WITH_IL5_DN | MSigDB lists | BYSTROEM_CORRELATED_WITH_IL5_DN | 63 | 15 | 17377 | 2626 |
FOXM1,NVL,ADAM10,IL6ST,SF3B1,TFDP1,BAZ1B,BCL2,PITPNB,MATR3,MXD1,DDB1,SRSF1,CAND1,PAPOLA |
| 4.559e-02 | -3.09 | SWEET_KRAS_TARGETS_DN | MSigDB lists | SWEET_KRAS_TARGETS_DN | 63 | 15 | 17377 | 2626 |
MLX,H2AFY,RRM2,KRAS,EBNA1BP2,EIF5,ATP6V1B2,RGS2,H3F3A,ODC1,LRP8,APP,POLR3K,BYSL,SSRP1 |
| 4.562e-02 | -3.09 | RNA methyltransferase activity | molecular function | GO:0008173 | 62 | 15 | 17224 | 2647 |
METTL1,NOP2,METTL14,CMTR2,WDR4,NSUN2,METTL2A,FTSJ1,TRMT10B,FBL,METTL3,MRM3,FTSJ3,NSUN4,MRM2 |
| 4.565e-02 | -3.09 | NAAA (N-acylethanolamine acid amidase) | protein interactions | 27163 | 54 | 14 | 17029 | 2761 |
SGSH,SEC23IP,ERF,OAF,NAGLU,SLC38A10,NHLRC3,CYB5R1,SYVN1,SCARB1,TTC17,EDEM2,ARSK,APP |
| 4.565e-02 | -3.09 | FNTB (farnesyltransferase, CAAX box, beta) | protein interactions | 2342 | 54 | 14 | 17029 | 2761 |
NAP1L1,FNTA,RPRD1A,FAM53C,CAST,CENPF,PTP4A3,KRAS,SPDL1,PITHD1,HRAS,CAPN1,NPLOC4,DHX57 |
| 4.565e-02 | -3.09 | NIT1 (nitrilase 1) | protein interactions | 4817 | 54 | 14 | 17029 | 2761 |
NUDT19,BOLA3,NUDT8,IDE,NDUFA11,TOP3A,TAZ,PITRM1,ACSF2,CAPN1,ECH1,SSSCA1,MRM2,BCAT2 |
| 4.565e-02 | -3.09 | BAD (BCL2 associated agonist of cell death) | protein interactions | 572 | 54 | 14 | 17029 | 2761 |
PPP3CA,KEAP1,EWSR1,SYNCRIP,LIMK1,RPS6KA1,RAF1,SUMO2,MCL1,YWHAZ,BCL2,BCL2L1,PRKACA,YWHAH |
| 4.565e-02 | -3.09 | CASP9 (caspase 9) | protein interactions | 842 | 54 | 14 | 17029 | 2761 |
CAPN2,RB1,BIRC3,BIRC5,GMEB1,XIAP,CYCS,BRCA1,BCL2L1,LYN,MAPK1,BIRC2,MAP2K2,MAPK3 |
| 4.565e-02 | -3.09 | PGRMC1 (progesterone receptor membrane component 1) | protein interactions | 10857 | 54 | 14 | 17029 | 2761 |
RPA2,DDOST,SCAP,ILF3,CUL3,DNAAF5,SRSF3,ADRB2,VDAC1,DUSP22,BCAP31,NCDN,CENPU,RPA1 |
| 4.570e-02 | -3.09 | V$ETS2_B | MSigDB lists | V$ETS2_B | 262 | 50 | 17377 | 2626 |
TCF12,PPP1R12A,CLSPN,CAST,TSC22D3,SESTD1,RAC1,ACTR3,DLGAP4,CTCF,DOCK11,PSEN1,LYN,FOXO3,RAB11A,BZW2,GIT2,RTKN,MCTS1,SLC31A1,VASP,STRBP,CDKN1B,AP2B1,CITED2,CDK12,ZNF800,RLIM,POU2AF1,SP3,EIF5A,PPP1R9B,BAZ2A,VDAC2,E2F3,ARHGDIB,LRP5,ARHGEF12,WDR81,PITPNB,EIF3K,ELMO1,FAM110A,SAFB,CORO1C,RWDD4,CEBPG,ARAP1,IMPDH1,ZMAT3 |
| 4.576e-02 | -3.08 | GSE557_WT_VS_CIITA_KO_DC_UP | MSigDB lists | GSE557_WT_VS_CIITA_KO_DC_UP | 186 | 37 | 17377 | 2626 |
TOR3A,GNE,STRN4,ACAP1,ARFIP2,IKBIP,COMMD5,APH1B,REEP5,COPG2,HMG20A,CCDC28A,RRP36,OIP5,NUDT19,PA2G4,NUS1,RRBP1,SOCS6,SLC35A1,ADCY7,SOCS5,PDLIM2,NTPCR,TIMM8B,ATP13A1,EID1,ZMYND11,MRPL43,SREK1,TMEM147,SFXN5,SRSF1,ORMDL2,DGCR8,TFDP2,SLC25A39 |
| 4.576e-02 | -3.08 | GSE8685_IL2_ACT_IL2_STARVED_VS_IL15_ACT_IL2_STARVED_CD4_TCELL_DN | MSigDB lists | GSE8685_IL2_ACT_IL2_STARVED_VS_IL15_ACT_IL2_STARVED_CD4_TCELL_DN | 186 | 37 | 17377 | 2626 |
PWWP2A,BCCIP,NPHP4,AGPAT1,TKT,SLC35B1,SNRPD3,POLR3K,NDUFS4,FANCL,PARL,TAP2,OSTC,CNNM3,MCPH1,C12orf75,NAA35,TMX1,SPTAN1,TDP1,IDH3A,PSPC1,DCUN1D5,TTC33,TWISTNB,MID1IP1,DDOST,FAM110A,CAMKMT,NDUFA11,WDR4,ATE1,KHSRP,NUP62,NDUFS5,PDSS2,GCSH |
| 4.576e-02 | -3.08 | GSE3982_NEUTROPHIL_VS_NKCELL_UP | MSigDB lists | GSE3982_NEUTROPHIL_VS_NKCELL_UP | 186 | 37 | 17377 | 2626 |
DDX58,UBE2D3,CYTIP,PLXNC1,NDUFB6,IVNS1ABP,ADAM10,B4GALT5,RAF1,ACTR3,SLC25A44,DAZAP2,ATP6V1B2,LYN,GIT2,MXD1,DNAJB9,CFLAR,ARPC5,PELO,PPP4R1,CAPZA1,PPP6C,IMPA2,MYO5A,SRPK2,BRD4,PFKFB3,SH3GLB1,MTMR3,UPF1,GOLGA2,TAB2,STAT1,VCPIP1,PSAP,NCOA1 |
| 4.576e-02 | -3.08 | GSE14908_RESTING_VS_HDM_STIM_CD4_TCELL_NONATOPIC_PATIENT_UP | MSigDB lists | GSE14908_RESTING_VS_HDM_STIM_CD4_TCELL_NONATOPIC_PATIENT_UP | 186 | 37 | 17377 | 2626 |
TMUB1,WDR13,BRAP,PCSK7,CSNK2A1,ARGLU1,SECISBP2,SEC16A,ANKIB1,CMTM6,MYL6B,CSDE1,CYB5RL,ARF5,PPCDC,INTS12,AQR,NSUN4,USP34,AKT2,NARF,WIPF1,CBFA2T2,DHX15,PAF1,PPP2CA,SEC31A,FBXO21,MBIP,SMAD2,SERF2,DHX16,WNT5B,GADD45B,HIPK3,CSNK1D,CAPN1 |
| 4.576e-02 | -3.08 | GSE17721_12H_VS_24H_CPG_BMDC_UP | MSigDB lists | GSE17721_12H_VS_24H_CPG_BMDC_UP | 186 | 37 | 17377 | 2626 |
DNMT3A,RHOC,TBC1D13,DNAJB1,CDKN2C,CLIC4,GART,RAD23B,AP2B1,NDUFS8,TARDBP,ALDH18A1,TFG,SENP1,RPP25,SNX2,ANKRD33B,USP42,MKI67,SEPT8,EZR,PKMYT1,ASB13,PSMB9,FAS,SMAD2,PPP2R5A,CDC27,CCDC86,SNAP23,SNAP29,CHMP4B,RGL1,AKNA,RUFY3,BRWD3,ANXA11 |
| 4.576e-02 | -3.08 | GSE39820_TGFBETA1_VS_TGFBETA3_IN_IL6_IL23A_TREATED_CD4_TCELL_DN | MSigDB lists | GSE39820_TGFBETA1_VS_TGFBETA3_IN_IL6_IL23A_TREATED_CD4_TCELL_DN | 186 | 37 | 17377 | 2626 |
MIF,GALK1,UNK,TMEM203,GPR89A,SNX15,FLOT1,ARGLU1,SLC35B2,IL21R,BZW2,APP,SAP130,MLX,PPIL2,MECR,RNF135,FBXL19,PTPRK,UBE2QL1,USP34,SAP30,ANKRD37,RNF25,NLN,GLO1,DCUN1D5,PCGF1,TOMM40,GOSR1,TXNL4A,C1orf122,TPD52L2,RAB24,SIAH2,GPR89B,AAAS |
| 4.576e-02 | -3.08 | GSE42724_NAIVE_VS_MEMORY_BCELL_DN | MSigDB lists | GSE42724_NAIVE_VS_MEMORY_BCELL_DN | 186 | 37 | 17377 | 2626 |
COX15,H2AFZ,FAM129A,C5orf30,GLUD1,CUTC,ANKIB1,PIP4K2A,PRKD3,CLIC4,NSRP1,CENPJ,H2AFY,AFF1,NUP153,STAT3,ARID4A,SAP30,ACSL5,VOPP1,PGGT1B,AKT2,RPL38,RPS10,RPS9,PEX5,KEAP1,PPP2R5A,CCDC86,CCDC6,HIPK2,LUC7L3,RPS14,BBX,RBMS1,YWHAZ,LRCH1 |
| 4.576e-02 | -3.08 | GSE37533_PPARG2_FOXP3_VS_FOXP3_TRANSDUCED_CD4_TCELL_DN | MSigDB lists | GSE37533_PPARG2_FOXP3_VS_FOXP3_TRANSDUCED_CD4_TCELL_DN | 186 | 37 | 17377 | 2626 |
DDX58,CYLD,PARP12,NF1,TAP1,ARID5A,XIAP,BTN3A1,HLA-A,GOLM1,PSMA6,CTNNBL1,SP100,ZCCHC2,TAP2,FBXL7,SCYL3,TRIM14,ACSL5,BAK1,TRAFD1,LAP3,BAZ2A,MCL1,DNAJA1,OGFR,LY6E,PSMB9,ISG15,RHBDF2,HLA-B,VEZF1,TRIM26,STAT1,SIAH2,PML,APOL2 |
| 4.576e-02 | -3.08 | GSE43955_TH0_VS_TGFB_IL6_TH17_ACT_CD4_TCELL_20H_DN | MSigDB lists | GSE43955_TH0_VS_TGFB_IL6_TH17_ACT_CD4_TCELL_20H_DN | 186 | 37 | 17377 | 2626 |
TCF12,DNAJC5,MAGEH1,DNMT3A,PCSK7,HAUS4,MAN2B1,SLC20A1,PARN,VMP1,ZNF639,ARHGEF2,RNF19A,CITED2,TGFB1,IFRD1,KLF10,RPL6,EMP3,PSMG1,MRPL16,WBP1,C9orf40,TXNL4A,KLF6,COMMD4,SPPL2B,RHOB,CHCHD3,PPP2R5A,ACOX1,STAT6,PRDX5,SSNA1,PPP5C,CDK2,OAZ1 |
| 4.582e-02 | -3.08 | ARID | prosite domains | PS51011 | 15 | 5 | 12060 | 1670 |
ARID1A,ARID2,ARID1B,ARID4A,ARID5A |
| 4.582e-02 | -3.08 | POST_SET | prosite domains | PS50868 | 15 | 5 | 12060 | 1670 |
KMT2B,NSD3,ASH1L,KMT2C,SUV39H2 |
| 4.582e-02 | -3.08 | OTU | prosite domains | PS50802 | 15 | 5 | 12060 | 1670 |
OTUD5,VCPIP1,OTUD3,ZRANB1,TNFAIP3 |
| 4.582e-02 | -3.08 | AA_TRNA_LIGASE_I | prosite domains | PS00178 | 15 | 5 | 12060 | 1670 |
LARS,EPRS,IARS,QARS,IARS2 |
| 4.585e-02 | -3.08 | actomyosin contractile ring | cellular component | GO:0005826 | 6 | 3 | 18223 | 2701 |
MYH9,ANLN,RTKN |
| 4.585e-02 | -3.08 | Bcl-2 family protein complex | cellular component | GO:0097136 | 6 | 3 | 18223 | 2701 |
BAK1,MCL1,BCL2L1 |
| 4.585e-02 | -3.08 | equatorial microtubule organizing center | cellular component | GO:0000923 | 6 | 3 | 18223 | 2701 |
MZT1,TUBGCP2,TUBGCP5 |
| 4.585e-02 | -3.08 | R2TP complex | cellular component | GO:0097255 | 6 | 3 | 18223 | 2701 |
RPAP3,RUVBL2,ECD |
| 4.585e-02 | -3.08 | ripoptosome | cellular component | GO:0097342 | 6 | 3 | 18223 | 2701 |
TICAM1,FADD,CFLAR |
| 4.585e-02 | -3.08 | integral component of cytoplasmic side of endoplasmic reticulum membrane | cellular component | GO:0071458 | 6 | 3 | 18223 | 2701 |
PKD2,SPPL2B,SPPL2A |
| 4.585e-02 | -3.08 | Barr body | cellular component | GO:0001740 | 6 | 3 | 18223 | 2701 |
H2AFY,H2AFZ,H3F3A |
| 4.585e-02 | -3.08 | catalytic step 1 spliceosome | cellular component | GO:0071012 | 6 | 3 | 18223 | 2701 |
XAB2,CRNKL1,PRPF19 |
| 4.585e-02 | -3.08 | EKC/KEOPS complex | cellular component | GO:0000408 | 6 | 3 | 18223 | 2701 |
TP53RK,OSGEPL1,LAGE3 |
| 4.585e-02 | -3.08 | DNA replication factor C complex | cellular component | GO:0005663 | 6 | 3 | 18223 | 2701 |
PCNA,RFC3,RFC2 |
| 4.586e-02 | -3.08 | regulation of defense response to virus | biological process | GO:0050688 | 68 | 16 | 17256 | 2622 |
DDX58,BIRC3,TNFAIP3,CGAS,DHX9,PQBP1,STAT1,EIF2AK4,IL12RB1,MAVS,IRF3,RNF26,ELMOD2,BIRC2,NPLOC4,PCBP2 |
| 4.592e-02 | -3.08 | PDGFB (platelet derived growth factor subunit B) | protein interactions | 5155 | 79 | 19 | 17029 | 2761 |
RPS15,PDAP1,TEX10,RPL15,BMS1,EBNA1BP2,UTP3,BUD13,BRIX1,KRI1,NSA2,MDM2,RBM34,MRPL27,NOC2L,RPF2,NKAPD1,MRPL13,HRAS |
| 4.592e-02 | -3.08 | USP8 (ubiquitin specific peptidase 8) | protein interactions | 9101 | 79 | 19 | 17029 | 2761 |
CHMP2A,SLBP,KIF23,RAB3IP,USP22,ARMH3,CHMP2B,UBE2I,STAM,USP21,CFLAR,PTEN,STAT6,PTAR1,YWHAZ,TARDBP,TATDN1,CHMP7,MCPH1 |
| 4.592e-02 | -3.08 | NRDC (nardilysin convertase) | protein interactions | 4898 | 79 | 19 | 17029 | 2761 |
NCOR2,PPP3CA,LYRM4,PPP1R12A,NSUN2,CHCHD2,LUC7L,RCC1L,PPP2CA,PFDN5,BOLA3,SEPT1,CLK3,CHCHD1,MSH2,ATP5F1A,APOOL,MOB1A,PDIA6 |
| 4.593e-02 | -3.08 | Noncanonical Wnt signaling pathway | Pathway Interaction DB | wnt_noncanonical_pathway | 30 | 10 | 2226 | 426 |
RHOA,CDC42,TAB2,RAC1,NFATC2,ROCK1,DVL1,CSNK1A1,ARRB2,DVL2 |
| 4.593e-02 | -3.08 | MAP2K and MAPK activation | REACTOME pathways | R-HSA-5674135 | 39 | 11 | 10287 | 1696 |
RAP1A,NRAS,CSK,RAF1,LAMTOR3,KRAS,MAPK1,ARRB2,HRAS,MAP2K2,MAPK3 |
| 4.593e-02 | -3.08 | Paradoxical activation of RAF signaling by kinase inactive BRAF | REACTOME pathways | R-HSA-6802955 | 39 | 11 | 10287 | 1696 |
RAP1A,NRAS,CSK,RAF1,BRAP,KRAS,MAPK1,ARRB2,HRAS,MAP2K2,MAPK3 |
| 4.593e-02 | -3.08 | Signaling by moderate kinase activity BRAF mutants | REACTOME pathways | R-HSA-6802946 | 39 | 11 | 10287 | 1696 |
RAP1A,NRAS,CSK,RAF1,BRAP,KRAS,MAPK1,ARRB2,HRAS,MAP2K2,MAPK3 |
| 4.593e-02 | -3.08 | Apoptotic cleavage of cellular proteins | REACTOME pathways | R-HSA-111465 | 39 | 11 | 10287 | 1696 |
FNTA,ADD1,CLSPN,CASP6,PLEC,ROCK1,GAS2,BCAP31,BIRC2,LMNA,SPTAN1 |
| 4.593e-02 | -3.08 | DNA Damage Recognition in GG-NER | REACTOME pathways | R-HSA-5696394 | 39 | 11 | 10287 | 1696 |
COPS8,RBX1,RPS27A,RAD23B,ACTB,COPS7B,INO80E,COPS6,YY1,DDB1,RAD23A |
| 4.601e-02 | -3.08 | Pathways in cancer | KEGG pathways | hsa05200 | 395 | 76 | 7161 | 1149 |
MAX,RAF1,SLC2A1,RAC1,XIAP,BCL2L1,PRKACA,BIRC2,GNB2,CRKL,MDM2,CDC42,RALB,PIK3R2,ADCY9,CDKN1B,TFG,F2R,DVL2,ADCY7,NRAS,BIRC3,RBX1,VHL,AKT2,GNG7,E2F3,SMAD2,JAK1,AXIN1,STAT1,ITGB1,DVL1,ROCK1,MAPK1,E2F2,TRAF5,SMAD4,HDAC2,CYCS,ETS1,FZD6,FGFR3,RB1,PTEN,ARHGEF1,DAPK1,MSH2,AXIN2,BCL2,STAT3,GNAI2,MSH6,TGFB1,RHOA,ARHGEF12,KRAS,MAP2K2,APPL1,FADD,DAPK3,MAPK3,FAS,RXRB,GNAS,GNA12,BIRC5,CCDC6,WNT5B,E2F1,PIAS2,PML,CDK2,HRAS,CDKN2A,EGLN1 |
| 4.603e-02 | -3.08 | SLC1A2 (solute carrier family 1 member 2) | protein interactions | 6506 | 13 | 5 | 17029 | 2761 |
RPL32,RPL17,PML,RPL38,RPL23A |
| 4.603e-02 | -3.08 | LSM10 (LSM10, U7 small nuclear RNA associated) | protein interactions | 84967 | 13 | 5 | 17029 | 2761 |
SLBP,SNRPG,ZNF473,LSM6,CLNS1A |
| 4.603e-02 | -3.08 | SFXN4 (sideroflexin 4) | protein interactions | 119559 | 13 | 5 | 17029 | 2761 |
NDUFA4,MTMR12,CLN3,ZNF746,BABAM1 |
| 4.603e-02 | -3.08 | PAIP2 (poly(A) binding protein interacting protein 2) | protein interactions | 51247 | 13 | 5 | 17029 | 2761 |
IGBP1,APP,PABPC1,PAIP1,RPL11 |
| 4.603e-02 | -3.08 | DMBT1 (deleted in malignant brain tumors 1) | protein interactions | 1755 | 13 | 5 | 17029 | 2761 |
DDX31,SNX27,ICE2,COPS6,EID1 |
| 4.603e-02 | -3.08 | ZCCHC9 (zinc finger CCHC-type containing 9) | protein interactions | 84240 | 13 | 5 | 17029 | 2761 |
NIFK,MAK16,ZC3H3,GPATCH4,H2AFX |
| 4.603e-02 | -3.08 | IER3IP1 (immediate early response 3 interacting protein 1) | protein interactions | 51124 | 13 | 5 | 17029 | 2761 |
TK1,RGS2,ADCY9,FAM3C,CYSTM1 |
| 4.603e-02 | -3.08 | TEFM (transcription elongation factor, mitochondrial) | protein interactions | 79736 | 13 | 5 | 17029 | 2761 |
NPHP4,KBTBD7,RCC1L,SDC2,CUL3 |
| 4.603e-02 | -3.08 | TST (thiosulfate sulfurtransferase) | protein interactions | 7263 | 13 | 5 | 17029 | 2761 |
MRPL50,SEPT11,HPDL,UBE2M,SNRPA |
| 4.603e-02 | -3.08 | RRAGD (Ras related GTP binding D) | protein interactions | 58528 | 13 | 5 | 17029 | 2761 |
RRAGC,LARS,TSC2,NOL8,LAMTOR3 |
| 4.603e-02 | -3.08 | AKIP1 (A-kinase interacting protein 1) | protein interactions | 56672 | 13 | 5 | 17029 | 2761 |
PRKACA,MCPH1,POC1A,POC5,SPTAN1 |
| 4.603e-02 | -3.08 | PARP14 (poly(ADP-ribose) polymerase family member 14) | protein interactions | 54625 | 13 | 5 | 17029 | 2761 |
RPA2,GPI,STAT6,HDAC2,RPA1 |
| 4.603e-02 | -3.08 | PGAM2 (phosphoglycerate mutase 2) | protein interactions | 5224 | 13 | 5 | 17029 | 2761 |
MDM2,NUTF2,BRD4,TXN,PGAM1 |
| 4.603e-02 | -3.08 | Atp5a1 (ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1) | protein interactions | 11946 | 13 | 5 | 17029 | 2761 |
CHCHD3,ATP5IF1,ATP5F1B,PTEN,ATP5PF |
| 4.603e-02 | -3.08 | BOLA2B (bolA family member 2B) | protein interactions | 654483 | 13 | 5 | 17029 | 2761 |
COX15,VDAC1,ARRB2,PARK7,CUL3 |
| 4.603e-02 | -3.08 | INPP5B (inositol polyphosphate-5-phosphatase B) | protein interactions | 3633 | 13 | 5 | 17029 | 2761 |
NUF2,FGFR1OP,RNASEH2A,SMURF1,APP |
| 4.603e-02 | -3.08 | ZNF274 (zinc finger protein 274) | protein interactions | 10782 | 13 | 5 | 17029 | 2761 |
MDM2,MRPS14,RPS27A,TRIM28,MRPL27 |
| 4.603e-02 | -3.08 | BOD1 (biorientation of chromosomes in cell division 1) | protein interactions | 91272 | 13 | 5 | 17029 | 2761 |
WDR5,CXXC1,APP,BTBD1,ATG4A |
| 4.603e-02 | -3.08 | CCDC91 (coiled-coil domain containing 91) | protein interactions | 55297 | 13 | 5 | 17029 | 2761 |
EWSR1,GGA2,GGA1,SYNRG,STARD7 |
| 4.603e-02 | -3.08 | ZXDC (ZXD family zinc finger C) | protein interactions | 79364 | 13 | 5 | 17029 | 2761 |
ATXN1,TK1,WDR5,APP,JTB |
| 4.603e-02 | -3.08 | CHD2 (chromodomain helicase DNA binding protein 2) | protein interactions | 1106 | 13 | 5 | 17029 | 2761 |
CTR9,PAF1,TRIM41,SRPK2,UHRF2 |
| 4.603e-02 | -3.08 | BRD9 (bromodomain containing 9) | protein interactions | 65980 | 13 | 5 | 17029 | 2761 |
CXXC4,NSD3,BRD4,SMARCD1,BCL7C |
| 4.603e-02 | -3.08 | MAT1A (methionine adenosyltransferase 1A) | protein interactions | 4143 | 13 | 5 | 17029 | 2761 |
MAT2B,RABIF,SHC1,VPS26C,MAT2A |
| 4.603e-02 | -3.08 | TMED3 (transmembrane p24 trafficking protein 3) | protein interactions | 23423 | 13 | 5 | 17029 | 2761 |
GORASP2,TMED10,GORASP1,OSBPL8,TMED2 |
| 4.603e-02 | -3.08 | JAKMIP2 (janus kinase and microtubule interacting protein 2) | protein interactions | 9832 | 13 | 5 | 17029 | 2761 |
HGS,MRPL11,SMARCE1,PIN1,ELOA |
| 4.603e-02 | -3.08 | GMEB2 (glucocorticoid modulatory element binding protein 2) | protein interactions | 26205 | 13 | 5 | 17029 | 2761 |
ATXN1,EWSR1,UBE2I,GMEB1,SDC2 |
| 4.608e-02 | -3.08 | CACTTTG,MIR-520G,MIR-520H | MSigDB lists | CACTTTG,MIR-520G,MIR-520H | 221 | 43 | 17377 | 2626 |
MAPRE1,ZFP91,PLAGL2,SUMF1,TGOLN2,ETS1,MIEN1,LHX8,AHCTF1,JAZF1,PPP6C,SOCS6,DNM2,SS18L1,MAP3K14,ERI3,SENP1,PPP3CA,ABHD2,CELSR2,C16orf72,CIC,DCAF8,WDR1,CUL3,ATXN1,MEF2D,EIF4G2,ARMC8,MACF1,MAT2A,TFEB,MKNK1,KPNA1,GOLGA7,TMEM168,LUC7L3,FASTK,LIMK1,PITX1,E2F1,FAM83D,ABCA1 |
| 4.616e-02 | -3.08 | nuclear hormone receptor binding | molecular function | GO:0035257 | 138 | 29 | 17224 | 2647 |
SLC30A9,NCOR2,TRIP12,BAZ2A,PHB2,WBP2,ARID5A,SMARCA4,HMGN3,THRAP3,BRCA1,ARID1A,PRMT2,KDM3A,PAGR1,PARK7,RB1,ETS2,BUD31,PIAS2,STAT1,NUP62,DDX5,FUS,NCOA1,RNF14,YWHAH,SMARCE1,NCOA2 |
| 4.619e-02 | -3.08 | Ufl1 (UFM1 specific ligase 1) | protein interactions | 67490 | 59 | 15 | 17029 | 2761 |
ASH1L,SEC61A1,STT3A,DGCR8,PHB2,ERLIN1,DYNLL1,UFC1,MRPS27,UHRF1BP1,TAF6,GAR1,GNB2,CAMK2G,DDRGK1 |
| 4.619e-02 | -3.08 | EXOSC1 (exosome component 1) | protein interactions | 51013 | 59 | 15 | 17029 | 2761 |
EXOSC6,EIF2S2,EXOSC7,ZCCHC8,RPL17,TBL3,PTAR1,BAZ1B,EXOSC9,UPF2,METTL22,RPL27A,RFC2,APP,CDC37 |
| 4.619e-02 | -3.08 | MED29 (mediator complex subunit 29) | protein interactions | 55588 | 59 | 15 | 17029 | 2761 |
OIP5,CCNC,POLR2I,PCM1,MED8,MED10,POLR2G,POLR2L,POLR2J,BIRC5,MED15,POLR2D,MED13L,MED22,POLR2A |
| 4.619e-02 | -3.08 | ANAPC5 (anaphase promoting complex subunit 5) | protein interactions | 51433 | 59 | 15 | 17029 | 2761 |
CDC16,CDC27,PTEN,CDT1,C16orf87,TFDP1,MAPK6,E2F1,ANAPC2,ANAPC7,CDC23,SMURF1,PABPC1,ANAPC4,FBXO5 |
| 4.619e-02 | -3.08 | UBE2G2 (ubiquitin conjugating enzyme E2 G2) | protein interactions | 7327 | 59 | 15 | 17029 | 2761 |
MDM2,HNRNPAB,KDM2A,RBX1,CPOX,TMEM216,RFFL,CORO1A,RNF26,ECPAS,CNNM3,HNRNPDL,RNF139,RNF5,NDUFS4 |
| 4.619e-02 | -3.07 | immunological synapse | cellular component | GO:0001772 | 33 | 9 | 18223 | 2701 |
SNX27,PDCD6IP,DUSP3,SOCS6,MYH9,EZR,CORO1A,CD81,STOML2 |
| 4.625e-02 | -3.07 | MID1 (midline 1) | protein interactions | 4281 | 74 | 18 | 17029 | 2761 |
UBE2D3,UBE2E2,PSMA1,KRAS,UBE2V1,GMCL1,EFL1,SPAG5,FKBP1A,PPP2CA,PSMD2,MID1IP1,PSMA6,PSMD3,IGBP1,PSMC1,BYSL,TUBB |
| 4.625e-02 | -3.07 | STX5 (syntaxin 5) | protein interactions | 6811 | 74 | 18 | 17029 | 2761 |
IMMT,USO1,TACC1,TMEM216,GOSR1,PSEN1,LMNA,EVC2,NSF,SNAP23,FAAP100,SNAP29,STX18,NSFL1C,TNPO3,VCPIP1,ASNA1,COPS6 |
| 4.625e-02 | -3.07 | EIF3D (eukaryotic translation initiation factor 3 subunit D) | protein interactions | 8664 | 74 | 18 | 17029 | 2761 |
EIF3L,STAU1,RPL35,CYLD,RAF1,SRSF5,MCM2,EIF1B,EIF3G,MATR3,RPS9,EIF3H,EIF3A,RPL23A,CAND1,EIF3K,ZNF746,EIF5 |
| 4.625e-02 | -3.07 | TUBA3C (tubulin alpha 3c) | protein interactions | 7278 | 74 | 18 | 17029 | 2761 |
CCT2,HJURP,VHL,DYNLL1,ZNF416,CUL3,UTP3,MCM2,SPAG5,PFDN5,PTEN,SIAH1,PML,YWHAZ,FBL,CD81,ARRB2,ATP6V0D1 |
| 4.625e-02 | -3.07 | WRAP73 (WD repeat containing, antisense to TP73) | protein interactions | 49856 | 74 | 18 | 17029 | 2761 |
CCT2,SMAP1,GNB2,CNOT9,MTMR3,PSMD2,PCM1,PSMD3,KLHL15,CENPJ,ODF2,OGT,LRPPRC,CEP63,CDK2,SASS6,SSSCA1,CCAR1 |
| 4.625e-02 | -3.07 | CHCHD3 (coiled-coil-helix-coiled-coil-helix domain containing 3) | protein interactions | 54927 | 74 | 18 | 17029 | 2761 |
SUZ12,RAB7A,TCF3,TOR1AIP1,NDUFA4,RAB3IP,SNRPD3,TOMM40,VDAC1,DUSP22,SDHA,SPAG5,FANCL,RAB8A,GOLGA2,APOOL,MTX2,NUDT3 |
| 4.628e-02 | -3.07 | Signaling by TGF-beta Receptor Complex in Cancer | REACTOME pathways | R-HSA-3304351 | 9 | 4 | 10287 | 1696 |
FKBP1A,TGFB1,SMAD2,SMAD4 |
| 4.628e-02 | -3.07 | SHC-related events triggered by IGF1R | REACTOME pathways | R-HSA-2428933 | 9 | 4 | 10287 | 1696 |
KRAS,NRAS,SHC1,HRAS |
| 4.628e-02 | -3.07 | Integration of provirus | REACTOME pathways | R-HSA-162592 | 9 | 4 | 10287 | 1696 |
KPNA1,XRCC4,BANF1,XRCC5 |
| 4.628e-02 | -3.07 | RHO GTPases Activate Rhotekin and Rhophilins | REACTOME pathways | R-HSA-5666185 | 9 | 4 | 10287 | 1696 |
RHOA,RHOC,RHOB,RTKN |
| 4.631e-02 | -3.07 | Blc2-like_sf | interpro domains | IPR036834 | 14 | 5 | 18492 | 2768 |
BCL2L12,BAK1,BCL2,MCL1,BCL2L1 |
| 4.631e-02 | -3.07 | Translation_prot_SH3-like_sf | interpro domains | IPR008991 | 14 | 5 | 18492 | 2768 |
EIF5A,MRPL2,MRPL19,RPL6,RPL8 |
| 4.631e-02 | -3.07 | Synthesis of substrates in N-glycan biosythesis | REACTOME pathways | R-HSA-446219 | 63 | 16 | 10287 | 1696 |
CMAS,GNPNAT1,TSTA3,DPM1,GNE,SLC17A5,AMDHD2,NANS,NEU1,NUS1,UAP1,ST3GAL2,CTSA,ST8SIA2,NANP,SLC35A1 |
| 4.633e-02 | -3.07 | lung-right_upper_lobe-carcinoma-bronchioloalveolar_adenocarcinoma | COSMIC cancer mutations | lung-right_upper_lobe-carcinoma-bronchioloalveolar_adenocarcinoma | 6 | 3 | 17385 | 2587 |
KIF5B,KRAS,EML4 |
| 4.633e-02 | -3.07 | salivary_gland-pharynx-carcinoma-adenoid_cystic_carcinoma | COSMIC cancer mutations | salivary_gland-pharynx-carcinoma-adenoid_cystic_carcinoma | 6 | 3 | 17385 | 2587 |
KRAS,NRAS,HRAS |
| 4.633e-02 | -3.07 | skin-buttock-benign_melanocytic_nevus-blue | COSMIC cancer mutations | skin-buttock-benign_melanocytic_nevus-blue | 6 | 3 | 17385 | 2587 |
KRAS,NRAS,HRAS |
| 4.633e-02 | -3.07 | skin-upper_leg-benign_melanocytic_nevus | COSMIC cancer mutations | skin-upper_leg-benign_melanocytic_nevus | 6 | 3 | 17385 | 2587 |
KRAS,NRAS,HRAS |
| 4.633e-02 | -3.07 | large_intestine-appendix-carcinoma-adenocarcinoma | COSMIC cancer mutations | large_intestine-appendix-carcinoma-adenocarcinoma | 6 | 3 | 17385 | 2587 |
GNAS,KRAS,SMAD4 |
| 4.633e-02 | -3.07 | central_nervous_system-pineal_gland-glioma-astrocytoma_Grade_I | COSMIC cancer mutations | central_nervous_system-pineal_gland-glioma-astrocytoma_Grade_I | 6 | 3 | 17385 | 2587 |
KRAS,NRAS,HRAS |
| 4.633e-02 | -3.07 | skin-upper_arm-benign_melanocytic_nevus | COSMIC cancer mutations | skin-upper_arm-benign_melanocytic_nevus | 6 | 3 | 17385 | 2587 |
KRAS,NRAS,HRAS |
| 4.633e-02 | -3.07 | skin-leg-other-atypical_Spitzoid_tumour | COSMIC cancer mutations | skin-leg-other-atypical_Spitzoid_tumour | 6 | 3 | 17385 | 2587 |
NRAS,HRAS,CDKN2A |
| 4.633e-02 | -3.07 | clavicle | COSMIC cancer mutations | clavicle | 6 | 3 | 17385 | 2587 |
RB1,FUS,CDKN2A |
| 4.633e-02 | -3.07 | skin-face-carcinoma-Merkel_cell_carcinoma | COSMIC cancer mutations | skin-face-carcinoma-Merkel_cell_carcinoma | 6 | 3 | 17385 | 2587 |
RB1,KRAS,NRAS |
| 4.633e-02 | -3.07 | salivary_gland-maxillary_sinus-carcinoma-adenoid_cystic_carcinoma | COSMIC cancer mutations | salivary_gland-maxillary_sinus-carcinoma-adenoid_cystic_carcinoma | 6 | 3 | 17385 | 2587 |
KRAS,NRAS,HRAS |
| 4.633e-02 | -3.07 | skin-chest-benign_melanocytic_nevus | COSMIC cancer mutations | skin-chest-benign_melanocytic_nevus | 6 | 3 | 17385 | 2587 |
KRAS,NRAS,HRAS |
| 4.633e-02 | -3.07 | skin-face-other-seborrhoeic_keratosis | COSMIC cancer mutations | skin-face-other-seborrhoeic_keratosis | 6 | 3 | 17385 | 2587 |
FGFR3,HRAS,PTPN11 |
| 4.633e-02 | -3.07 | skin-upper_leg-benign_melanocytic_nevus-blue | COSMIC cancer mutations | skin-upper_leg-benign_melanocytic_nevus-blue | 6 | 3 | 17385 | 2587 |
KRAS,NRAS,HRAS |
| 4.633e-02 | -3.07 | skin-shoulder-benign_melanocytic_nevus | COSMIC cancer mutations | skin-shoulder-benign_melanocytic_nevus | 6 | 3 | 17385 | 2587 |
KRAS,NRAS,HRAS |
| 4.633e-02 | -3.07 | spitzoid | COSMIC cancer mutations | spitzoid | 6 | 3 | 17385 | 2587 |
NRAS,HRAS,CDKN2A |
| 4.633e-02 | -3.07 | ischium | COSMIC cancer mutations | ischium | 6 | 3 | 17385 | 2587 |
EWSR1,H3F3A,CDKN2A |
| 4.633e-02 | -3.07 | nodular_fasciitis | COSMIC cancer mutations | nodular_fasciitis | 6 | 3 | 17385 | 2587 |
GNAS,FUS,ETV6 |
| 4.633e-02 | -3.07 | spindle_cell | COSMIC cancer mutations | spindle_cell | 6 | 3 | 17385 | 2587 |
GNAS,RB1,FUS |
| 4.633e-02 | -3.07 | maxillary_sinus | COSMIC cancer mutations | maxillary_sinus | 6 | 3 | 17385 | 2587 |
KRAS,NRAS,HRAS |
| 4.633e-02 | -3.07 | lymphoepithelioma_like_carcinoma | COSMIC cancer mutations | lymphoepithelioma_like_carcinoma | 6 | 3 | 17385 | 2587 |
KIF5B,KRAS,EML4 |
| 4.633e-02 | -3.07 | skin-lower_leg-benign_melanocytic_nevus | COSMIC cancer mutations | skin-lower_leg-benign_melanocytic_nevus | 6 | 3 | 17385 | 2587 |
KRAS,NRAS,HRAS |
| 4.633e-02 | -3.07 | skin-upper_arm-benign_melanocytic_nevus-blue | COSMIC cancer mutations | skin-upper_arm-benign_melanocytic_nevus-blue | 6 | 3 | 17385 | 2587 |
KRAS,NRAS,HRAS |
| 4.633e-02 | -3.07 | skin-forearm-malignant_melanoma-superficial_spreading | COSMIC cancer mutations | skin-forearm-malignant_melanoma-superficial_spreading | 6 | 3 | 17385 | 2587 |
KRAS,NRAS,HRAS |
| 4.633e-02 | -3.07 | skin-upper_leg-carcinoma-Merkel_cell_carcinoma | COSMIC cancer mutations | skin-upper_leg-carcinoma-Merkel_cell_carcinoma | 6 | 3 | 17385 | 2587 |
RB1,KRAS,NRAS |
| 4.633e-02 | -3.07 | skin-penis-carcinoma-squamous_cell_carcinoma | COSMIC cancer mutations | skin-penis-carcinoma-squamous_cell_carcinoma | 6 | 3 | 17385 | 2587 |
STK11,HRAS,CDKN2A |
| 4.633e-02 | -3.07 | bone-femur-chondrosarcoma-dedifferentiated | COSMIC cancer mutations | bone-femur-chondrosarcoma-dedifferentiated | 6 | 3 | 17385 | 2587 |
RB1,HRAS,CDKN2A |
| 4.633e-02 | -3.07 | soft_tissue-fibrous_tissue_and_uncertain_origin-nodular_fasciitis | COSMIC cancer mutations | soft_tissue-fibrous_tissue_and_uncertain_origin-nodular_fasciitis | 6 | 3 | 17385 | 2587 |
GNAS,FUS,ETV6 |
| 4.633e-02 | -3.07 | bone-extraskeletal-chondrosarcoma | COSMIC cancer mutations | bone-extraskeletal-chondrosarcoma | 6 | 3 | 17385 | 2587 |
RB1,FUS,CDKN2A |
| 4.633e-02 | -3.07 | stomach-other-hamartoma | COSMIC cancer mutations | stomach-other-hamartoma | 6 | 3 | 17385 | 2587 |
GNAS,KRAS,STK11 |
| 4.633e-02 | -3.07 | KBTBD7 (kelch repeat and BTB domain containing 7) | protein interactions | 84078 | 147 | 32 | 17029 | 2761 |
SARNP,TRIP12,UBXN1,MRPS26,RGS2,MAP1LC3B,PHC2,ZBTB21,FBXL6,WDR44,POP7,MRPL34,GTSE1,NSUN4,UBE2M,MRPL57,MRM2,TMEM160,RBX1,CREG1,PPP1R21,CUL3,ZNF574,NUP155,ERC1,KIF2A,TULP3,TPP2,MRPL27,ZNF598,NUMB,FAF1 |
| 4.639e-02 | -3.07 | negative regulation of DNA binding transcription factor activity | biological process | GO:0043433 | 168 | 34 | 17256 | 2622 |
USP7,CYLD,PHB2,DAP,EIF2AK4,COMMD6,MAD2L2,FZD6,WWP2,LRRC14,PRNP,RB1,SP100,GLIS2,SRI,RLIM,CHP1,TNFAIP3,ERBIN,MEN1,PRMT2,BRMS1,CAT,KEAP1,TONSL,NLRC5,CEBPG,PKD2,ARRB2,PARP10,FAF1,CDKN2A,HDAC2,EGLN1 |
| 4.639e-02 | -3.07 | nucleocytoplasmic carrier activity | molecular function | GO:0140142 | 18 | 6 | 17224 | 2647 |
KPNA2,KPNA4,KPNA1,SNUPN,NUTF2,XPO7 |
| 4.639e-02 | -3.07 | voltage-gated anion channel activity | molecular function | GO:0008308 | 18 | 6 | 17224 | 2647 |
CLCN3,VDAC1,GPR89A,GPR89B,CLCN6,VDAC2 |
| 4.643e-02 | -3.07 | GSE9316_IL6_KO_VS_IFNG_KO_INVIVO_EXPANDED_CD4_TCELL_DN | MSigDB lists | GSE9316_IL6_KO_VS_IFNG_KO_INVIVO_EXPANDED_CD4_TCELL_DN | 192 | 38 | 17377 | 2626 |
KARS,PARP12,AGRN,TOR3A,TOR1AIP1,GADD45G,TAP1,EBNA1BP2,CFLAR,CLIC4,IARS,FJX1,TPST1,PARL,OSTC,MVP,SGCB,SYTL3,PPA1,NSUN4,ABCC1,IFRD1,TRAFD1,TNFAIP3,LAP3,PGS1,OAF,TOR1AIP2,IL12RB1,OGFR,LSG1,TARS,UTP20,GADD45B,MAPK6,NFIL3,CHMP4B,NAA20 |
| 4.643e-02 | -3.07 | GSE41176_WT_VS_TAK1_KO_ANTI_IGM_STIM_BCELL_6H_DN | MSigDB lists | GSE41176_WT_VS_TAK1_KO_ANTI_IGM_STIM_BCELL_6H_DN | 192 | 38 | 17377 | 2626 |
NDUFV2,MRPL9,NUP188,IVNS1ABP,FLOT1,CREBL2,PPP3CB,BECN1,LYN,TFRC,CFLAR,RAD23A,VAV1,FARSA,PSMA6,TNFAIP8,PTEN,ATP6V0A2,ALDH9A1,TRAFD1,ACP2,BIRC3,TNFAIP3,ATP2C1,BMS1,UTP3,PDHX,MAK16,MAP3K4,POLR2J,ZNF330,TFDP1,STAT1,ARAP1,RUVBL2,MAP3K5,TUBB,ZBTB24 |
| 4.643e-02 | -3.07 | GSE32034_UNTREATED_VS_ROSIGLIZATONE_TREATED_LY6C_HIGH_MONOCYTE_UP | MSigDB lists | GSE32034_UNTREATED_VS_ROSIGLIZATONE_TREATED_LY6C_HIGH_MONOCYTE_UP | 192 | 38 | 17377 | 2626 |
GCLM,SCAMP3,ANK3,SLC2A1,TIA1,UCK1,RPL15,ABCB10,PMF1,IKBIP,PRKACA,KCMF1,RAD23A,PHC2,FARSA,STRBP,ARHGEF1,TIMELESS,FAM3A,ABCC1,CDC37,GPX4,PLK3,ERCC1,TIMP2,SEPT9,ELL2,ABCF2,CADM1,USP22,TANC1,ELK1,PEF1,GEMIN5,SLC19A1,NSF,RRS1,CSNK1D |
| 4.643e-02 | -3.07 | GSE22886_NAIVE_CD8_TCELL_VS_NKCELL_DN | MSigDB lists | GSE22886_NAIVE_CD8_TCELL_VS_NKCELL_DN | 192 | 38 | 17377 | 2626 |
RAB14,FGFR1OP,TRIP12,PPP1R12A,SRGN,ARID5A,DHX8,NOTCH2,LYN,BIRC2,CFLAR,SLC31A1,SEC24C,RAD23B,GMEB1,EXOSC1,AP2B1,KIFAP3,TARDBP,MAST2,MAML1,NCOA2,ENPP4,ABHD2,RHOBTB3,TACC1,TAOK1,NARF,ARHGEF12,RTF1,RHBDF2,MTMR3,PON2,GOLGA2,SNAP29,HIPK2,MIA2,IFI16 |
| 4.643e-02 | -3.07 | GSE37533_UNTREATED_VS_PIOGLIZATONE_TREATED_CD4_TCELL_PPARG1_AND_FOXP3_TRASDUCED_UP | MSigDB lists | GSE37533_UNTREATED_VS_PIOGLIZATONE_TREATED_CD4_TCELL_PPARG1_AND_FOXP3_TRASDUCED_UP | 192 | 38 | 17377 | 2626 |
ZNF207,CMAS,TXN,ADO,UCK2,CYCS,SCYL2,PARK7,CLIC4,TNFAIP8,DDA1,ATP13A3,SEPT11,CYC1,MINPP1,PPIF,METTL1,ABHD2,IDH3A,MAP4K4,RIT1,NUTF2,VDAC1,GAR1,PSMB3,EPB41,CCDC86,TTLL4,NIP7,ACOX1,CORO1C,C1orf109,PPA2,FKBP5,PDXK,SMURF1,CD81,NXT2 |
| 4.643e-02 | -3.07 | ZNHIT2 (zinc finger HIT-type containing 2) | protein interactions | 741 | 64 | 16 | 17029 | 2761 |
RPAP3,SART1,SNRNP200,DCAF8,USP39,NCDN,POLR2A,DDX23,FBXO3,EFTUD2,EIF2D,TCOF1,RUVBL2,ECD,VPS29,PRPF19 |
| 4.643e-02 | -3.07 | CLOCK (clock circadian regulator) | protein interactions | 9575 | 64 | 16 | 17029 | 2761 |
RORB,OIP5,TFAP4,CCDC93,MAX,CIPC,RPRD1A,GRIPAP1,RABGAP1L,ARNTL,RCOR1,CRY2,NUF2,PSMD9,HMG20A,GIT2 |
| 4.643e-02 | -3.07 | MARK3 (microtubule affinity regulating kinase 3) | protein interactions | 4140 | 64 | 16 | 17029 | 2761 |
DLG5,MEX3C,NOL11,HDAC7,DYNLL1,PRKAA1,CAPZA1,ATP6V0C,YWHAZ,CPSF4,ASB13,YWHAH,HNRNPDL,USP21,MARK2,TERF2 |
| 4.644e-02 | -3.07 | PLOD1 (procollagen-lysine,2-oxoglutarate 5-dioxygenase 1) | protein interactions | 5351 | 69 | 17 | 17029 | 2761 |
KDM3B,CHERP,CDCA3,CUL3,CUL1,C9orf40,ISG15,NCDN,CAND1,GEMIN5,KIF18B,U2SURP,ODF2,H2AFX,DUSP11,TERF1,TERF2 |
| 4.644e-02 | -3.07 | FOXO1 (forkhead box O1) | protein interactions | 2308 | 69 | 17 | 17029 | 2761 |
RECQL,TSC2,SMARCA4,DNAJC9,IRF3,SIRT2,CCNB1,PRKACA,RB1,MDM2,CSNK1G1,PITX1,PML,LRPPRC,YWHAZ,NCOA1,SMAD4 |
| 4.644e-02 | -3.07 | KCTD17 (potassium channel tetramerization domain containing 17) | protein interactions | 79734 | 69 | 17 | 17029 | 2761 |
CTU2,CYLD,RBX1,POLK,CUL3,CERK,KCTD17,PSMA1,MTMR6,ZNF696,OPTN,SUV39H2,RWDD4,ARRDC1,DUSP11,CBX4,CSNK1D |
| 4.644e-02 | -3.07 | EXOSC8 (exosome component 8) | protein interactions | 11340 | 69 | 17 | 17029 | 2761 |
RPA2,TFAP4,EXOSC6,EXOSC7,ZCCHC8,VHL,SNRPB,EXOSC1,COX5A,AEN,EXOSC9,UPF2,BRCA1,METTL22,ATF2,IFI16,RPA1 |
| 4.651e-02 | -3.07 | mandible | COSMIC cancer mutations | mandible | 28 | 8 | 17385 | 2587 |
GNAS,KRAS,FUS,EWSR1,NRAS,CDC73,HRAS,CDKN2A |
| 4.651e-02 | -3.07 | lip | COSMIC cancer mutations | lip | 28 | 8 | 17385 | 2587 |
FGFR3,NRAS,PTEN,VHL,KRAS,NOTCH2,HRAS,CDKN2A |
| 4.651e-02 | -3.07 | genital_tract-extragonadal-germ_cell_tumour-mixed | COSMIC cancer mutations | genital_tract-extragonadal-germ_cell_tumour-mixed | 28 | 8 | 17385 | 2587 |
CABIN1,KRAS,NRAS,KDM2A,NF1,PTEN,HRAS,ADAM23 |
| 4.651e-02 | -3.07 | central_nervous_system-occipital_lobe-glioma-astrocytoma_Grade_IV | COSMIC cancer mutations | central_nervous_system-occipital_lobe-glioma-astrocytoma_Grade_IV | 28 | 8 | 17385 | 2587 |
EIF2AK1,OSBP2,H3F3A,NF1,PTEN,CDKN2A,MSH6,MSH2 |
| 4.664e-02 | -3.07 | SARS2 (seryl-tRNA synthetase 2, mitochondrial) | protein interactions | 54938 | 35 | 10 | 17029 | 2761 |
TUFM,ILF3,CUL3,CHCHD2,NENF,DMWD,KCMF1,MATR3,TARS,SPTAN1 |
| 4.664e-02 | -3.07 | TOP3B (DNA topoisomerase III beta) | protein interactions | 8940 | 35 | 10 | 17029 | 2761 |
TRIM41,THOC1,POC1A,SNRPB,CENPF,GBA,CHIC2,UPF2,FXR1,RPA1 |
| 4.664e-02 | -3.07 | SETD1A (SET domain containing 1A) | protein interactions | 9739 | 35 | 10 | 17029 | 2761 |
ZNF207,USF1,PNISR,CXXC1,WDR82,BRCA1,PRMT2,WDR5,CTDSP2,POLR2A |
| 4.664e-02 | -3.07 | FAM3C (family with sequence similarity 3 member C) | protein interactions | 10447 | 35 | 10 | 17029 | 2761 |
GALNT2,SNAP23,FLOT1,MPV17,UBE4A,SRSF3,UBE3C,REEP5,LMNA,NDUFS7 |
| 4.664e-02 | -3.07 | PPP1R9A (protein phosphatase 1 regulatory subunit 9A) | protein interactions | 55607 | 35 | 10 | 17029 | 2761 |
ANKRD28,BCL2L12,PPP1R9B,PPP1R2,PRKAR1B,KCTD17,TGOLN2,CAPZA2,LRP8,WDR48 |
| 4.664e-02 | -3.07 | RCC1L (RCC1 like) | protein interactions | 81554 | 35 | 10 | 17029 | 2761 |
NUDT19,MRPL50,SYNCRIP,RBM42,STARD7,TBRG4,ATXN1,BRCA1,ECH1,RCC1L |
| 4.664e-02 | -3.07 | ARHGAP21 (Rho GTPase activating protein 21) | protein interactions | 57584 | 35 | 10 | 17029 | 2761 |
RHOA,AXIN1,ODF2,MYO18A,MYH9,ARF1,CAPZA2,ANLN,ARRB2,EEF1D |
| 4.664e-02 | -3.07 | UBR7 (ubiquitin protein ligase E3 component n-recognin 7 (putative)) | protein interactions | 55148 | 35 | 10 | 17029 | 2761 |
UBQLN4,C9orf78,GOLGA4,PDCD10,THOC1,HEXB,TATDN1,PDIA6,HEXA,RPAIN |
| 4.664e-02 | -3.07 | NOL9 (nucleolar protein 9) | protein interactions | 79707 | 35 | 10 | 17029 | 2761 |
PHF10,RPS2,AHNAK,SUMO2,TEX10,WDR18,KIAA0232,MRS2,SHCBP1,IFI16 |
| 4.664e-02 | -3.07 | RMND5B (required for meiotic nuclear division 5 homolog B) | protein interactions | 64777 | 35 | 10 | 17029 | 2761 |
UBE2D3,GID8,RMND5A,RAB8A,EWSR1,MKLN1,PIGT,UCK2,ARMC8,SMAD4 |
| 4.664e-02 | -3.07 | Eef1a1 (eukaryotic translation elongation factor 1 alpha 1) | protein interactions | 13627 | 35 | 10 | 17029 | 2761 |
EPRS,LARS,IARS,PTEN,PHB2,RRBP1,TOP2B,KTN1,EEF1D,VPS29 |
| 4.664e-02 | -3.07 | SMG7 (SMG7, nonsense mediated mRNA decay factor) | protein interactions | 9887 | 35 | 10 | 17029 | 2761 |
FGFR3,MDM2,CDC16,UPF1,PCM1,MTMR4,CENPJ,ODF2,RBM8A,SEC16A |
| 4.664e-02 | -3.07 | LYST (lysosomal trafficking regulator) | protein interactions | 1130 | 35 | 10 | 17029 | 2761 |
DAP3,HGS,TACC1,CENPJ,YWHAZ,CNTROB,GAR1,NCDN,HNRNPM,SAP30 |
| 4.664e-02 | -3.07 | Vps28 (vacuolar protein sorting 28) | protein interactions | 66914 | 35 | 10 | 17029 | 2761 |
SEC23IP,BAZ2A,CUTA,FLOT1,ATP6V0A1,ATP6V1B2,CHMP2B,MRPL3,ATP6V0D1,ATP6V1G1 |
| 4.667e-02 | -3.06 | GAS2 | pfam domains | PF02187 | 6 | 3 | 17054 | 2545 |
DST,GAS2,MACF1 |
| 4.667e-02 | -3.06 | DUF3669 | pfam domains | PF12417 | 6 | 3 | 17054 | 2545 |
ZNF282,ZNF777,ZNF746 |
| 4.667e-02 | -3.06 | RAP | pfam domains | PF08373 | 6 | 3 | 17054 | 2545 |
FASTKD3,TBRG4,FASTK |
| 4.667e-02 | -3.06 | DUF4749 | pfam domains | PF15936 | 6 | 3 | 17054 | 2545 |
PDLIM1,PDLIM5,PDLIM2 |
| 4.667e-02 | -3.06 | DUSP | pfam domains | PF06337 | 6 | 3 | 17054 | 2545 |
USP20,USP11,USP32 |
| 4.667e-02 | -3.06 | FAST_2 | pfam domains | PF08368 | 6 | 3 | 17054 | 2545 |
FASTKD3,TBRG4,FASTK |
| 4.667e-02 | -3.06 | Plectin | pfam domains | PF00681 | 6 | 3 | 17054 | 2545 |
DST,PLEC,MACF1 |
| 4.667e-02 | -3.06 | CAMSAP_CH | pfam domains | PF11971 | 6 | 3 | 17054 | 2545 |
VAV1,VAV2,CAMSAP1 |
| 4.667e-02 | -3.06 | Anticodon_1 | pfam domains | PF08264 | 6 | 3 | 17054 | 2545 |
LARS,IARS,IARS2 |
| 4.667e-02 | -3.06 | tRNA-synt_1 | pfam domains | PF00133 | 6 | 3 | 17054 | 2545 |
LARS,IARS,IARS2 |
| 4.667e-02 | -3.06 | SPOC | pfam domains | PF07744 | 6 | 3 | 17054 | 2545 |
DIDO1,RBM15,RBM15B |
| 4.667e-02 | -3.06 | Brix | pfam domains | PF04427 | 6 | 3 | 17054 | 2545 |
PPAN,RPF2,BRIX1 |
| 4.667e-02 | -3.06 | SMC_N | pfam domains | PF02463 | 6 | 3 | 17054 | 2545 |
SMC3,SMC2,SMC4 |
| 4.667e-02 | -3.06 | SMC_hinge | pfam domains | PF06470 | 6 | 3 | 17054 | 2545 |
SMC3,SMC2,SMC4 |
| 4.667e-02 | -3.06 | FAST_1 | pfam domains | PF06743 | 6 | 3 | 17054 | 2545 |
FASTKD3,TBRG4,FASTK |
| 4.667e-02 | -3.06 | Mg_trans_NIPA | pfam domains | PF05653 | 6 | 3 | 17054 | 2545 |
NIPAL3,NIPA2,NIPA1 |
| 4.675e-02 | -3.06 | GSE2128_CTRL_VS_MIMETOPE_NEGATIVE_SELECTION_DP_THYMOCYTE_NOD_DN | MSigDB lists | GSE2128_CTRL_VS_MIMETOPE_NEGATIVE_SELECTION_DP_THYMOCYTE_NOD_DN | 169 | 34 | 17377 | 2626 |
CTDP1,KIAA0100,TSC2,UQCR10,TKT,AKT1S1,ZER1,CDK5,IRF4,RAB8A,INTS7,TTC9C,ZNF746,FAM89B,ORAI1,MRPL48,PRADC1,TTLL12,CLTB,UBE2M,ZC3H3,MLST8,SPTAN1,PPP1R9B,SNRNP200,EMB,PACS1,PI4K2A,UBTF,TBC1D17,SLC38A7,STK11,PIEZO1,CCDC137 |
| 4.675e-02 | -3.06 | CYCLIN | smart domains | SM00385 | 34 | 9 | 9493 | 1367 |
CCNC,CCNK,RB1,CCNA2,RBL1,CCNL2,CCNB1,CCNF,CCNB2 |
| 4.678e-02 | -3.06 | Cytosolic sensors of pathogen-associated DNA | REACTOME pathways | R-HSA-1834949 | 68 | 17 | 10287 | 1696 |
POLR2L,CGAS,POLR2K,PRKDC,DHX9,POLR3GL,IRF3,APP,POLR3K,XRCC5,RPS27A,STAT6,DTX4,CRCP,TICAM1,TRIM32,IFI16 |
| 4.690e-02 | -3.06 | human chr11p13 | chromosome location | human chr11p13 | 45 | 9 | 26185 | 2809 |
FBXO3,CAT,CD59,FJX1,DNAJC24,ELP4,LDLRAD3,PDHX,HIPK3 |
| 4.690e-02 | -3.06 | V$HSF2_01 | MSigDB lists | V$HSF2_01 | 233 | 45 | 17377 | 2626 |
HSPH1,UBE2E2,CYLD,EWSR1,ST13,TRERF1,LAMTOR3,XPNPEP3,DNAJB1,MAPK14,BCAP31,ARL6IP6,CREM,HNRNPA2B1,FANCL,NFATC3,NEK6,SSBP3,KNTC1,EIF5,ABCC5,ELOVL5,TRIM8,LAP3,E2F3,ATXN1,PLEC,KCNQ1,KDM3A,EIF4G2,CCT8,MAT2A,GIGYF1,HSPA1B,KRIT1,ALKBH6,DDX17,SRSF1,DERL1,HLA-B,ZNF777,TAB2,MBD6,SMAD1,PDLIM5 |
| 4.700e-02 | -3.06 | AATGTGA,MIR-23A,MIR-23B | MSigDB lists | AATGTGA,MIR-23A,MIR-23B | 394 | 72 | 17377 | 2626 |
TMED7,SNX27,GGNBP2,KDM4A,XIAP,ATP6V1B2,FANCI,NEK6,ZCCHC2,RAD23B,SOCS6,PDIA6,GCC1,CCAR1,RYBP,PPIF,CLCN3,TLK1,MAP4K4,CUL3,WBP2,ATXN1,LRP5,CADM1,MCFD2,DHX15,MAT2A,EIF3A,BRWD1,CLK3,CAB39,NCOA1,ATMIN,PRPF4B,UBE2D3,CDC40,MAPRE1,PKP4,PPP1R12A,EYA1,CTCF,TOP2B,MEX3C,INPP5A,BUD31,AFF1,MDFIC,CPSF4,MAML1,CSNK1G3,FOXK1,C16orf72,BTAF1,DENND1B,RTF1,CBFA2T2,BORA,PICALM,HMGN2,FAS,NAP1L1,KPNA1,KPNA4,RBM25,CCDC6,OSBPL8,CSNK1G1,PITPNA,HMGB2,MAP3K5,CPEB2,S100PBP |
| 4.701e-02 | -3.06 | Signaling by NOTCH1 | REACTOME pathways | R-HSA-1980143 | 73 | 18 | 10287 | 1696 |
MIB2,CCNC,NCOR2,ADAM17,KAT2A,ADAM10,RBX1,APH1A,CUL1,APH1B,RPS27A,HDAC7,DTX4,RBPJ,MAML1,ARRB2,HDAC2,NUMB |
| 4.702e-02 | -3.06 | Oncostatin M Signaling Pathway | WikiPathways | WP2374 | 66 | 16 | 5312 | 837 |
RAF1,KRAS,MAPK14,MAP2K2,MAPK3,SHC1,JAK1,IL6ST,STAT1,PTPN11,CDKN1B,CREB1,CDK2,MAPK1,STAT3,HRAS |
| 4.702e-02 | -3.06 | AGE/RAGE pathway | WikiPathways | WP2324 | 66 | 16 | 5312 | 837 |
RHOA,SMAD2,CDC42,DDOST,SHC1,RAF1,RAC1,STAT1,EZR,CYCS,ROCK1,STAT3,MAPK1,ATF2,MAPK14,MAPK3 |
| 4.702e-02 | -3.06 | mucinous | COSMIC cancer mutations | mucinous | 38 | 10 | 17385 | 2587 |
GNAS,FGFR3,NRAS,PTEN,SF3B1,KRAS,BRCA1,ARID1A,SMAD4,CDKN2A |
| 4.704e-02 | -3.06 | GO_POSITIVE_REGULATION_OF_CELL_DEATH | MSigDB lists | GO_POSITIVE_REGULATION_OF_CELL_DEATH | 589 | 104 | 17377 | 2626 |
DNMT3A,CYLD,TRAF7,NQO1,NF1,DYNLL1,RAC1,MAGED1,PLAGL2,SIRT2,BCL2L1,LYN,PARK7,BCAP31,MOAP1,CDK5,VAV1,CDC42,SIAH1,SIVA1,PIN1,DNM2,CDKN1B,PDCD2,TP53BP2,F2R,ATF2,SENP1,HTRA2,SRPK2,BAK1,PPIF,NCK1,APH1A,RNPS1,DDX20,MCL1,DNAJA1,SOX4,PRKRA,STK17B,BRMS1,RPS27A,GADD45B,ITGB1,ZNF268,NCOA1,CHEK2,CLU,ZMAT3,PDCD4,DAP,TRIO,GADD45G,VAV2,TIA1,B4GALT1,CYCS,PAWR,IP6K2,APH1B,PSEN1,FOXO3,APOPT1,JMY,PTPN2,TFAP4,CTNNBL1,PTEN,ZNF746,DAPK1,AXIN2,ANXA5,ARHGEF2,BCL2,CREB1,UBE2M,TGFB1,NET1,PRKDC,LDHA,HEBP2,ARHGEF12,BCLAF1,ADRB2,ELK1,PRMT2,PICALM,IRF5,FADD,DAPK3,RHOB,FAS,PDCD6,TFDP1,PPP3R1,PML,E2F1,YWHAZ,MAP3K5,YWHAH,TERF1,FAF1,CDKN2A |
| 4.705e-02 | -3.06 | V$TFIII_Q6 | MSigDB lists | V$TFIII_Q6 | 198 | 39 | 17377 | 2626 |
TCF12,MAX,PLXNC1,ADAM10,PHF23,WDTC1,HCFC1R1,LMNA,BCAT2,TFAP4,CD3EAP,UTP18,PPIG,RAB35,ANP32A,UPF2,STAT3,STRAP,CDK12,CYFIP1,PPP1R9B,BAZ2A,MTA2,LDB1,MAP4K3,WDR81,NUTF2,CBFA2T2,KRTCAP2,RAB5B,NCDN,UBTF,GNAS,CORO1C,ST3GAL2,NR2F2,CBX4,CAPN1,ATXN7L2 |
| 4.705e-02 | -3.06 | Val/Leu/Ile-tRNA-synth_edit | interpro domains | IPR009008 | 6 | 3 | 18492 | 2768 |
LARS,IARS,IARS2 |
| 4.705e-02 | -3.06 | M/V/L/I-tRNA-synth_anticd-bd | interpro domains | IPR013155 | 6 | 3 | 18492 | 2768 |
LARS,IARS,IARS2 |
| 4.705e-02 | -3.06 | DUF3669_Znf | interpro domains | IPR022137 | 6 | 3 | 18492 | 2768 |
ZNF282,ZNF777,ZNF746 |
| 4.705e-02 | -3.06 | VOC | interpro domains | IPR037523 | 6 | 3 | 18492 | 2768 |
GLO1,HPDL,GLOD4 |
| 4.705e-02 | -3.06 | SPOC_C | interpro domains | IPR012921 | 6 | 3 | 18492 | 2768 |
DIDO1,RBM15,RBM15B |
| 4.705e-02 | -3.06 | Mg_trans_NIPA | interpro domains | IPR008521 | 6 | 3 | 18492 | 2768 |
NIPAL3,NIPA2,NIPA1 |
| 4.705e-02 | -3.06 | DUF4749 | interpro domains | IPR031847 | 6 | 3 | 18492 | 2768 |
PDLIM1,PDLIM5,PDLIM2 |
| 4.705e-02 | -3.06 | Rad51_DMC1_RadA | interpro domains | IPR033925 | 6 | 3 | 18492 | 2768 |
RAD51C,XRCC3,RAD51D |
| 4.705e-02 | -3.06 | FAST_2 | interpro domains | IPR013579 | 6 | 3 | 18492 | 2768 |
FASTKD3,TBRG4,FASTK |
| 4.705e-02 | -3.06 | SWIB_MDM2_dom_sf | interpro domains | IPR036885 | 6 | 3 | 18492 | 2768 |
MDM2,EIF2D,SMARCD1 |
| 4.705e-02 | -3.06 | Glyas_Bleomycin-R_OHBP_Dase | interpro domains | IPR029068 | 6 | 3 | 18492 | 2768 |
GLO1,HPDL,GLOD4 |
| 4.705e-02 | -3.06 | GAR_dom_sf | interpro domains | IPR036534 | 6 | 3 | 18492 | 2768 |
DST,GAS2,MACF1 |
| 4.705e-02 | -3.06 | CAMSAP_CH | interpro domains | IPR022613 | 6 | 3 | 18492 | 2768 |
VAV1,VAV2,CAMSAP1 |
| 4.705e-02 | -3.06 | RCMT | interpro domains | IPR023267 | 6 | 3 | 18492 | 2768 |
NOP2,NSUN4,NSUN2 |
| 4.705e-02 | -3.06 | SMC_hinge | interpro domains | IPR010935 | 6 | 3 | 18492 | 2768 |
SMC3,SMC2,SMC4 |
| 4.705e-02 | -3.06 | GAR_dom | interpro domains | IPR003108 | 6 | 3 | 18492 | 2768 |
DST,GAS2,MACF1 |
| 4.705e-02 | -3.06 | aa-tRNA-synth_Ia | interpro domains | IPR002300 | 6 | 3 | 18492 | 2768 |
LARS,IARS,IARS2 |
| 4.705e-02 | -3.06 | SMC_hinge_sf | interpro domains | IPR036277 | 6 | 3 | 18492 | 2768 |
SMC3,SMC2,SMC4 |
| 4.705e-02 | -3.06 | Brix | interpro domains | IPR007109 | 6 | 3 | 18492 | 2768 |
RPF2,PPAN,BRIX1 |
| 4.705e-02 | -3.06 | RAP | interpro domains | IPR013584 | 6 | 3 | 18492 | 2768 |
FASTKD3,TBRG4,FASTK |
| 4.705e-02 | -3.06 | FAST_Leu-rich | interpro domains | IPR010622 | 6 | 3 | 18492 | 2768 |
FASTKD3,TBRG4,FASTK |
| 4.705e-02 | -3.06 | RecF/RecN/SMC_N | interpro domains | IPR003395 | 6 | 3 | 18492 | 2768 |
SMC3,SMC2,SMC4 |
| 4.705e-02 | -3.06 | DNA_pol3_clamp-load_cplx_C | interpro domains | IPR008921 | 6 | 3 | 18492 | 2768 |
RFC3,RFC2,WRNIP1 |
| 4.705e-02 | -3.06 | Coatomer/calthrin_app_sub_C | interpro domains | IPR009028 | 6 | 3 | 18492 | 2768 |
AP2B1,AP1B1,COPG2 |
| 4.705e-02 | -3.06 | DNA_recomb/repair_RecA-like | interpro domains | IPR016467 | 6 | 3 | 18492 | 2768 |
RAD51C,XRCC3,RAD51D |
| 4.706e-02 | -3.06 | RAO_BOUND_BY_SALL4_ISOFORM_B | MSigDB lists | RAO_BOUND_BY_SALL4_ISOFORM_B | 485 | 87 | 17377 | 2626 |
PTMS,IER2,NDUFA5,LUZP1,GPBP1L1,IVNS1ABP,PPP1R15B,TBC1D13,BIRC2,MOAP1,KIFC1,DST,ZNF428,TCEA1,ATF2,RHBDD2,DRAM2,CGGBP1,SP3,SHOC2,CLCN3,NCK1,ANLN,PEF1,SHCBP1,DDX17,PPP2CA,ANKRD10,FBXO28,HINT1,GRIPAP1,TFDP2,RTN3,MYL12B,ANXA11,PARD3,ADAM23,DDX58,WSB2,RMND5A,CMAS,GCLM,NDUFS1,KIAA0100,TM9SF4,TOR3A,HABP4,DBF4,ZNRF3,LYRM2,COPG2,SLC25A36,MCTS1,MAT2B,PPP1R3B,CCP110,FEM1B,OSTF1,MRPL11,CITED2,ZRANB1,ZNF189,SOCS5,EIF5A,ZFP64,TMEM39A,RB1CC1,PRRC2A,NQO2,EMB,LDB1,MAP4K3,PNPLA8,SRSF5,C9orf40,AKAP1,RAB18,PDLIM1,TTLL4,L3MBTL3,ELMO1,KLHL15,PML,RBPJ,MAP3K5,CPEB2,PURA |
| 4.717e-02 | -3.05 | GO_REGULATION_OF_ATPASE_ACTIVITY | MSigDB lists | GO_REGULATION_OF_ATPASE_ACTIVITY | 58 | 14 | 17377 | 2626 |
PPIF,DNAJC10,DNAJC2,AHSA1,TOR1AIP1,RAB4A,DNM2,DNAJC24,DNAJC9,TOR1AIP2,ADRB2,DNAJB1,SNRNP70,CHTOP |
| 4.717e-02 | -3.05 | MODULE_525 | MSigDB lists | MODULE_525 | 58 | 14 | 17377 | 2626 |
FYTTD1,ORAI2,SNRNP200,MIOS,INTS7,KLHL15,NSUN2,DBF4,TRAK1,PTPN11,AEN,NMD3,DHX15,NUP205 |
| 4.717e-02 | -3.05 | GO_REGULATION_OF_PROTEIN_TYROSINE_KINASE_ACTIVITY | MSigDB lists | GO_REGULATION_OF_PROTEIN_TYROSINE_KINASE_ACTIVITY | 58 | 14 | 17377 | 2626 |
PTPN2,SH3BP5,HSPH1,FGFR1OP,ADAM17,SHC1,SOCS4,MVP,PSEN1,ABI1,APP,LRP8,DVL2,SOCS5 |
| 4.720e-02 | -3.05 | cutaneous_T_cell_lymphoma | COSMIC cancer mutations | cutaneous_T_cell_lymphoma | 33 | 9 | 17385 | 2587 |
FGFR3,RB1,NRAS,PTEN,VHL,STK11,KRAS,HRAS,CDKN2A |
| 4.720e-02 | -3.05 | haematopoietic_and_lymphoid_tissue-skin-lymphoid_neoplasm-cutaneous_T_cell_lymphoma | COSMIC cancer mutations | haematopoietic_and_lymphoid_tissue-skin-lymphoid_neoplasm-cutaneous_T_cell_lymphoma | 33 | 9 | 17385 | 2587 |
FGFR3,RB1,NRAS,PTEN,VHL,STK11,KRAS,HRAS,CDKN2A |
| 4.728e-02 | -3.05 | IWANAGA_CARCINOGENESIS_BY_KRAS_DN | MSigDB lists | IWANAGA_CARCINOGENESIS_BY_KRAS_DN | 118 | 25 | 17377 | 2626 |
SP3,PDCD6IP,PIGN,KIAA0040,MOGS,PITPNB,RGS2,SAFB2,ITGB5,SRSF1,CRKL,TERF2IP,CDC16,PTEN,HNRNPR,LIMK1,NSMCE2,PPP1R11,INTS12,SNRPG,PIK3IP1,MAP3K14,NR2F2,CTDSP2,TRIM14 |
| 4.728e-02 | -3.05 | GSE2770_IL12_VS_TGFB_AND_IL12_TREATED_ACT_CD4_TCELL_2H_UP | MSigDB lists | GSE2770_IL12_VS_TGFB_AND_IL12_TREATED_ACT_CD4_TCELL_2H_UP | 118 | 25 | 17377 | 2626 |
ANKRD33B,CAMSAP1,CREBL2,CDK13,BOLA1,ATG2B,DIDO1,CCNF,DOCK11,TOLLIP,ARF4,ECH1,EDC3,DTL,DLG5,CLUAP1,ATP6V1D,CCNA2,CHD3,DNAJC17,CNPY4,CEP63,CCDC125,ALDH9A1,CSTF1 |
| 4.729e-02 | -3.05 | RARA (retinoic acid receptor alpha) | protein interactions | 5914 | 126 | 28 | 17029 | 2761 |
USP7,NCOR2,MTA2,SUZ12,GADD45G,ARID5A,TOP2B,ARID1A,PRMT2,MBD3,FAS,RXRB,SAP130,MDM2,TMEM54,SIAH1,PIN1,ARNTL,MAPK6,PML,E2F1,MECR,ANP32A,TRIM32,NCOA1,MAPK1,NCOA2,HDAC2 |
| 4.738e-02 | -3.05 | Activated NOTCH1 Transmits Signal to the Nucleus | REACTOME pathways | R-HSA-2122948 | 30 | 9 | 10287 | 1696 |
MIB2,ADAM17,ADAM10,APH1A,RPS27A,DTX4,APH1B,ARRB2,NUMB |
| 4.738e-02 | -3.05 | Pre-NOTCH Transcription and Translation | REACTOME pathways | R-HSA-1912408 | 30 | 9 | 10287 | 1696 |
KAT2A,AGO2,TFDP1,E2F1,E2F3,NOTCH2,RBPJ,TFDP2,MAML1 |
| 4.743e-02 | -3.05 | GO_RUFFLE | MSigDB lists | GO_RUFFLE | 152 | 31 | 17377 | 2626 |
DDX58,WASF2,CYFIP1,PPP1R9B,ADAM17,MKLN1,AKT2,RAC1,CIB1,EZR,MYH9,WIPF1,ARFIP2,MYO9B,ATP6V1B2,MACF1,RAB22A,ARF4,PIP5K1C,GNAS,PDXP,KIF18A,RINL,ITGB1,DNM2,ARHGEF2,ROCK1,S100A6,CFL1,ALS2,MYO5A |
| 4.743e-02 | -3.05 | GSE29614_CTRL_VS_TIV_FLU_VACCINE_PBMC_2007_DN | MSigDB lists | GSE29614_CTRL_VS_TIV_FLU_VACCINE_PBMC_2007_DN | 152 | 31 | 17377 | 2626 |
GINS1,SEC61B,FOXM1,PBK,CENPF,MRPL12,MKI67,KIF15,RRM2,NUF2,SMC2,CHAC2,CCNB1,MCM2,SHCBP1,NCAPG,SDHA,SPAG5,DDX17,DTL,OIP5,TRAM2,DSN1,TMEM168,CDC27,KIF14,SEC24C,PHTF1,CEP55,B4GALT3,CCNB2 |
| 4.746e-02 | -3.05 | late endosome membrane | cellular component | GO:0031902 | 126 | 26 | 18223 | 2701 |
CHMP2A,CLCN3,ANXA6,ATG9A,RAB7A,CDIP1,LAMTOR3,VTI1A,WDR81,CHMP2B,TMEM165,RHOB,RMC1,SPPL2A,SCARB2,HGS,OSBPL11,CHMP4A,LAMTOR4,CHMP4B,VPS4A,PIKFYVE,WDR91,TMEM9,SNX14,STARD3NL |
| 4.748e-02 | -3.05 | FYVE | smart domains | SM00064 | 29 | 8 | 9493 | 1367 |
MTMR3,HGS,MTMR4,ZFYVE27,ZFYVE21,PIKFYVE,RUFY1,PLEKHF2 |
| 4.749e-02 | -3.05 | regulation of cellular amine metabolic process | biological process | GO:0033238 | 79 | 18 | 17256 | 2622 |
NQO1,PSMA8,PSMB7,PSMA1,PSMD9,PSMB9,ODC1,PARK7,PSMB3,PSMC4,PSMD2,PSMA6,PSMD1,PSMD8,PSMD3,OAZ2,OAZ1,PSMC1 |
| 4.749e-02 | -3.05 | positive regulation of neuron death | biological process | GO:1901216 | 79 | 18 | 17256 | 2622 |
RHOA,NQO1,NF1,MYBL2,MCL1,ELK1,PICALM,FOXO3,PRNP,CDK5,PIN1,ZNF746,TP53BP2,CLU,MAP3K5,ATF2,UBE2M,SRPK2 |
| 4.750e-02 | -3.05 | regulation of protein import into nucleus | biological process | GO:0042306 | 63 | 15 | 17256 | 2622 |
TGFB1,TXN,PIK3R2,RAB23,NUP54,NUP62,MDFIC,NUTF2,MAVS,PSEN1,MAPK1,MAPK14,NUP58,TRIM28,CHP1 |
| 4.757e-02 | -3.05 | GSE7831_CPG_VS_INFLUENZA_STIM_PDC_4H_UP | MSigDB lists | GSE7831_CPG_VS_INFLUENZA_STIM_PDC_4H_UP | 175 | 35 | 17377 | 2626 |
PPP1R37,DDX47,TMUB1,MAGED1,AP3M2,XPO7,PARN,PARK7,RFWD3,PA2G4,ZNF420,SAR1A,RBM34,IMPAD1,MECR,CNPY4,TTC3,UBE3B,MRPL11,EIF5,TXNL1,TIMP2,LDB1,RAB3IP,PRMT2,MAP3K4,TBC1D17,ACOX1,C1orf109,STAT1,CRCP,GPI,BEND3,CLU,ZMAT3 |
| 4.757e-02 | -3.05 | GSE2770_UNTREATED_VS_ACT_CD4_TCELL_6H_UP | MSigDB lists | GSE2770_UNTREATED_VS_ACT_CD4_TCELL_6H_UP | 175 | 35 | 17377 | 2626 |
HIVEP3,PPIB,ZCCHC9,GMFG,GNPDA1,RRAGC,NIT2,GTF3A,TMED3,REEP5,RAB11A,MFSD10,SSR1,APLP2,SSBP3,BDH1,SRI,BRI3,UBE2M,ABI1,PDLIM2,ANKRD37,VHL,MRPL43,EIF2A,EDEM2,EIF3K,SEC61A1,TWSG1,SNAP23,SNAP29,COX8A,SLC25A19,IGBP1,E2F2 |
| 4.759e-02 | -3.05 | translation regulator activity | molecular function | GO:0045182 | 52 | 13 | 17224 | 2647 |
SAMD4B,MIF4GD,RPS14,CIRBP,EIF2AK1,EIF2AK4,FXR1,CPEB2,RPS9,PURA,PABPC1,PAIP1,PAIP2 |
| 4.767e-02 | -3.04 | GROSS_HYPOXIA_VIA_ELK3_AND_HIF1A_UP | MSigDB lists | GROSS_HYPOXIA_VIA_ELK3_AND_HIF1A_UP | 135 | 28 | 17377 | 2626 |
NAGPA,FAM49B,VHL,SRGN,MAGED1,SLC2A1,PFKFB3,RCOR1,CHIC2,LRP5,JMJD6,ETS1,KLF6,MXD1,PSMC4,PPP1R3B,SLC19A1,HOMER1,NAP1L1,SERTAD2,ZNF330,PRDX5,MAPK6,APPL2,SIAH2,RBPJ,PGAM1,RPS6KC1 |
| 4.784e-02 | -3.04 | GO_CELL_PROLIFERATION | MSigDB lists | GO_CELL_PROLIFERATION | 651 | 114 | 17377 | 2626 |
TXN,CKLF,RPS6KA1,RAF1,RAC1,TPX2,CUL1,KIF2C,BCL2L1,DUSP22,TCF19,MXD1,RPL23A,CDK5,RRN3,PA2G4,PCNA,KIF14,ETV6,TXLNA,PDS5B,ECD,PLCL2,NAA35,DVL2,TACC3,PRPF19,BAK1,PLK1,ERCC1,MAPRE2,KLF10,MKI67,KIF15,FRAT2,PSMG1,AURKB,CADM1,AZI2,SOX4,GINS4,HHEX,CDC16,STAT6,STAT1,UHRF2,SCARB1,PDXK,CLU,SMAD1,MAPK1,NAA60,SMAD4,NUMB,USP13,MIF,POU3F2,MAPRE1,MCM10,PDAP1,CENPF,DCTN2,RRM1,BTN3A1,RACGAP1,PPP3CB,ZNRF3,CDK11B,PSEN1,SRRT,FZD6,FGFR3,EIF2S2,PTEN,PPP1R8,PELO,PRDM4,ARHGEF1,AXIN2,BCL2,FBXL7,ORC3,CITED2,GNAI2,STAT3,NUDC,GINS1,TGFB1,TK1,NASP,KAT2A,TACC1,CREG1,ASPM,ZMYND11,PRKDC,APPL1,PICALM,MAP2K2,PRDX1,XRCC5,PCM1,CDC27,PALB2,TFDP1,APPL2,FAM83D,IMPDH1,NDE1,BTBD10,CD81,HRAS,BYSL,IFI16 |
| 4.784e-02 | -3.04 | FERRANDO_HOX11_NEIGHBORS | MSigDB lists | FERRANDO_HOX11_NEIGHBORS | 23 | 7 | 17377 | 2626 |
PTPRF,ERCC1,TK1,CCNA2,STMN1,MCM5,RPA1 |
| 4.784e-02 | -3.04 | GO_PROTEASOME_ACCESSORY_COMPLEX | MSigDB lists | GO_PROTEASOME_ACCESSORY_COMPLEX | 23 | 7 | 17377 | 2626 |
PSMD2,PSMD1,PSMD9,PSMC1,PSMD8,PSMD3,PSMC4 |
| 4.784e-02 | -3.04 | GO_REGULATION_OF_PROTEIN_PHOSPHATASE_TYPE_2A_ACTIVITY | MSigDB lists | GO_REGULATION_OF_PROTEIN_PHOSPHATASE_TYPE_2A_ACTIVITY | 23 | 7 | 17377 | 2626 |
ANKLE2,PPP2R5A,IGBP1,PPME1,PPP2R2D,MASTL,ENSA |
| 4.784e-02 | -3.04 | GO_CLATHRIN_VESICLE_COAT | MSigDB lists | GO_CLATHRIN_VESICLE_COAT | 23 | 7 | 17377 | 2626 |
AP2B1,AP1S1,CLTB,SYNRG,AP2S1,PICALM,NECAP2 |
| 4.784e-02 | -3.04 | BIOCARTA_RAC1_PATHWAY | MSigDB lists | BIOCARTA_RAC1_PATHWAY | 23 | 7 | 17377 | 2626 |
CDK5,ARFIP2,VAV1,LIMK1,CFL1,RAC1,TRIO |
| 4.784e-02 | -3.04 | REACTOME_ACTIVATION_OF_GENES_BY_ATF4 | MSigDB lists | REACTOME_ACTIVATION_OF_GENES_BY_ATF4 | 23 | 7 | 17377 | 2626 |
KHSRP,EXOSC9,ATF6,EXOSC6,EXOSC7,PARN,EXOSC1 |
| 4.784e-02 | -3.04 | GO_SCF_DEPENDENT_PROTEASOMAL_UBIQUITIN_DEPENDENT_PROTEIN_CATABOLIC_PROCESS | MSigDB lists | GO_SCF_DEPENDENT_PROTEASOMAL_UBIQUITIN_DEPENDENT_PROTEIN_CATABOLIC_PROCESS | 23 | 7 | 17377 | 2626 |
FBXO9,CUL1,FBXL7,FBXL3,CCNF,RBX1,KIF14 |
| 4.784e-02 | -3.04 | GO_MEMBRANE_LIPID_CATABOLIC_PROCESS | MSigDB lists | GO_MEMBRANE_LIPID_CATABOLIC_PROCESS | 23 | 7 | 17377 | 2626 |
SMPD4,GALC,PPT1,GM2A,NEU1,HEXB,GBA |
| 4.784e-02 | -3.04 | GO_ORGANOPHOSPHATE_ESTER_TRANSMEMBRANE_TRANSPORTER_ACTIVITY | MSigDB lists | GO_ORGANOPHOSPHATE_ESTER_TRANSMEMBRANE_TRANSPORTER_ACTIVITY | 23 | 7 | 17377 | 2626 |
SLC25A19,SLC35B1,SLC35B2,SLC35A1,SLC25A33,SLC35B4,SLC25A36 |
| 4.784e-02 | -3.04 | BIOCARTA_PTDINS_PATHWAY | MSigDB lists | BIOCARTA_PTDINS_PATHWAY | 23 | 7 | 17377 | 2626 |
PDPK1,ARHGEF2,ARF1,LYN,PFKP,VAV2,RAC1 |
| 4.784e-02 | -3.04 | MULLIGAN_NTF3_SIGNALING_VIA_INSR_AND_IGF1R_UP | MSigDB lists | MULLIGAN_NTF3_SIGNALING_VIA_INSR_AND_IGF1R_UP | 23 | 7 | 17377 | 2626 |
USP10,EBNA1BP2,HSPA4,SERP1,CORO1C,TMEM97,SRXN1 |
| 4.784e-02 | -3.04 | GO_LIGAND_DEPENDENT_NUCLEAR_RECEPTOR_BINDING | MSigDB lists | GO_LIGAND_DEPENDENT_NUCLEAR_RECEPTOR_BINDING | 23 | 7 | 17377 | 2626 |
SLC30A9,NCOR2,NCOA1,ARID1A,BAZ2A,SMARCE1,NCOA2 |
| 4.784e-02 | -3.04 | REACTOME_PROCESSING_OF_CAPPED_INTRONLESS_PRE_MRNA | MSigDB lists | REACTOME_PROCESSING_OF_CAPPED_INTRONLESS_PRE_MRNA | 23 | 7 | 17377 | 2626 |
SLBP,SNRPG,ZNF473,SNRPD3,SNRPB,PAPOLA,CSTF1 |
| 4.784e-02 | -3.04 | AZARE_STAT3_TARGETS | MSigDB lists | AZARE_STAT3_TARGETS | 23 | 7 | 17377 | 2626 |
B4GALT1,MCL1,NUP188,CLIC4,COPA,SRSF6,DHX9 |
| 4.784e-02 | -3.04 | GO_NEGATIVE_REGULATION_OF_CELL_CYCLE_G2_M_PHASE_TRANSITION | MSigDB lists | GO_NEGATIVE_REGULATION_OF_CELL_CYCLE_G2_M_PHASE_TRANSITION | 23 | 7 | 17377 | 2626 |
H2AFY,GPR132,CCNA2,BLM,ZNF830,CLSPN,FANCI |
| 4.784e-02 | -3.04 | BIOCARTA_CASPASE_PATHWAY | MSigDB lists | BIOCARTA_CASPASE_PATHWAY | 23 | 7 | 17377 | 2626 |
ARHGDIB,CYCS,BIRC3,CASP6,BIRC2,LMNA,XIAP |
| 4.784e-02 | -3.04 | GO_NUCLEAR_TRANSCRIBED_MRNA_POLY_A_TAIL_SHORTENING | MSigDB lists | GO_NUCLEAR_TRANSCRIBED_MRNA_POLY_A_TAIL_SHORTENING | 23 | 7 | 17377 | 2626 |
CNOT6,CNOT6L,EIF4A3,PARN,PABPC1,PAIP1,CNOT3 |
| 4.784e-02 | -3.04 | AKL_HTLV1_INFECTION_UP | MSigDB lists | AKL_HTLV1_INFECTION_UP | 23 | 7 | 17377 | 2626 |
AP2B1,SOX4,NET1,APP,MAP4K4,RAB4A,ACLY |
| 4.794e-02 | -3.04 | LisH | interpro domains | IPR006594 | 28 | 8 | 18492 | 2768 |
GID8,RMND5A,FGFR1OP,TCOF1,MKLN1,FOPNL,SSBP3,SMU1 |
| 4.796e-02 | -3.04 | Integrin-mediated Cell Adhesion | WikiPathways | WP185 | 103 | 23 | 5312 | 837 |
PDPK1,RAF1,AKT2,RAC1,VAV2,ITGB5,MAP2K2,GIT2,CAPN2,RAP1A,VASP,ITGB8,CDC42,SHC1,CSK,MAPK6,CAPN7,PIK3R2,ITGB1,ROCK1,MAPK1,HRAS,CAPN1 |
| 4.797e-02 | -3.04 | TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) | REACTOME pathways | R-HSA-2173791 | 17 | 6 | 10287 | 1696 |
TGFB1,FKBP1A,RHOA,SMURF1,RPS27A,PARD3 |
| 4.797e-02 | -3.04 | SUMOylation of transcription factors | REACTOME pathways | R-HSA-3232118 | 17 | 6 | 10287 | 1696 |
SP3,MDM2,UBE2I,MTA1,SUMO2,CDKN2A |
| 4.799e-02 | -3.04 | ABC_transporter_CS | interpro domains | IPR017871 | 43 | 11 | 18492 | 2768 |
ABCA3,ABCC10,ABCF2,TAP1,ABCB10,TAP2,ABCD1,ABCA1,ABCF1,ABCC5,ABCC1 |
| 4.800e-02 | -3.04 | REACTOME_OXYGEN_DEPENDENT_PROLINE_HYDROXYLATION_OF_HYPOXIA_INDUCIBLE_FACTOR_ALPHA | MSigDB lists | REACTOME_OXYGEN_DEPENDENT_PROLINE_HYDROXYLATION_OF_HYPOXIA_INDUCIBLE_FACTOR_ALPHA | 14 | 5 | 17377 | 2626 |
UBE2D3,RBX1,RPS27A,VHL,EGLN1 |
| 4.800e-02 | -3.04 | GO_REGULATION_OF_SPINDLE_ASSEMBLY | MSigDB lists | GO_REGULATION_OF_SPINDLE_ASSEMBLY | 14 | 5 | 17377 | 2626 |
PLK1,CHMP2A,CHMP4B,PDCD6IP,CHMP2B |
| 4.800e-02 | -3.04 | GO_TRANSCRIPTION_FACTOR_TFTC_COMPLEX | MSigDB lists | GO_TRANSCRIPTION_FACTOR_TFTC_COMPLEX | 14 | 5 | 17377 | 2626 |
TAF2,TAF5L,TAF12,KAT2A,TAF6 |
| 4.800e-02 | -3.04 | SILIGAN_TARGETS_OF_EWS_FLI1_FUSION_UP | MSigDB lists | SILIGAN_TARGETS_OF_EWS_FLI1_FUSION_UP | 14 | 5 | 17377 | 2626 |
TCF12,RHOBTB3,NAA35,MDH2,TAOK1 |
| 4.800e-02 | -3.04 | GO_HISTONE_H3_K9_MODIFICATION | MSigDB lists | GO_HISTONE_H3_K9_MODIFICATION | 14 | 5 | 17377 | 2626 |
BEND3,SUV39H2,KDM3A,ARID4A,EHMT1 |
| 4.800e-02 | -3.04 | BIOCARTA_PS1_PATHWAY | MSigDB lists | BIOCARTA_PS1_PATHWAY | 14 | 5 | 17377 | 2626 |
ADAM17,RBPJ,DVL1,PSEN1,AXIN1 |
| 4.800e-02 | -3.04 | GO_STRESS_FIBER_ASSEMBLY | MSigDB lists | GO_STRESS_FIBER_ASSEMBLY | 14 | 5 | 17377 | 2626 |
RHOA,PDCD10,ITGB5,CUL3,ITGB1 |
| 4.800e-02 | -3.04 | XU_RESPONSE_TO_TRETINOIN_UP | MSigDB lists | XU_RESPONSE_TO_TRETINOIN_UP | 14 | 5 | 17377 | 2626 |
CDKN2C,WIPF1,ADD3,WAS,PSMB9 |
| 4.800e-02 | -3.04 | REACTOME_TRAF3_DEPENDENT_IRF_ACTIVATION_PATHWAY | MSigDB lists | REACTOME_TRAF3_DEPENDENT_IRF_ACTIVATION_PATHWAY | 14 | 5 | 17377 | 2626 |
DDX58,SIKE1,IRF3,MAVS,RNF135 |
| 4.800e-02 | -3.04 | V$AHRARNT_02 | MSigDB lists | V$AHRARNT_02 | 14 | 5 | 17377 | 2626 |
AMPD2,NRF1,MAPRE1,HINT1,SUPT16H |
| 4.800e-02 | -3.04 | GO_N_ACETYLGLUCOSAMINE_METABOLIC_PROCESS | MSigDB lists | GO_N_ACETYLGLUCOSAMINE_METABOLIC_PROCESS | 14 | 5 | 17377 | 2626 |
AMDHD2,GNPNAT1,NANP,GNPDA1,GNE |
| 4.800e-02 | -3.04 | GO_IMP_METABOLIC_PROCESS | MSigDB lists | GO_IMP_METABOLIC_PROCESS | 14 | 5 | 17377 | 2626 |
ADSS,AMPD2,ADSL,GART,ATIC |
| 4.800e-02 | -3.04 | BIOCARTA_DREAM_PATHWAY | MSigDB lists | BIOCARTA_DREAM_PATHWAY | 14 | 5 | 17377 | 2626 |
CREB1,POLR2A,MAPK3,PRKAR1B,CREM |
| 4.800e-02 | -3.04 | GO_NEGATIVE_REGULATION_OF_PHOSPHOPROTEIN_PHOSPHATASE_ACTIVITY | MSigDB lists | GO_NEGATIVE_REGULATION_OF_PHOSPHOPROTEIN_PHOSPHATASE_ACTIVITY | 14 | 5 | 17377 | 2626 |
FKBP1A,PPP1R11,CRY2,ROCK1,MASTL |
| 4.800e-02 | -3.04 | GO_TROPHECTODERMAL_CELL_DIFFERENTIATION | MSigDB lists | GO_TROPHECTODERMAL_CELL_DIFFERENTIATION | 14 | 5 | 17377 | 2626 |
CTR9,SP3,BYSL,CNOT3,CUL3 |
| 4.800e-02 | -3.04 | ZHAN_V1_LATE_DIFFERENTIATION_GENES_DN | MSigDB lists | ZHAN_V1_LATE_DIFFERENTIATION_GENES_DN | 14 | 5 | 17377 | 2626 |
CSK,DNMT1,SNRPB,PTPN7,MRPS27 |
| 4.800e-02 | -3.04 | GO_ANTIGEN_PROCESSING_AND_PRESENTATION_OF_ENDOGENOUS_PEPTIDE_ANTIGEN | MSigDB lists | GO_ANTIGEN_PROCESSING_AND_PRESENTATION_OF_ENDOGENOUS_PEPTIDE_ANTIGEN | 14 | 5 | 17377 | 2626 |
HLA-B,TAP2,HLA-E,HLA-A,TAP1 |
| 4.800e-02 | -3.04 | CASTELLANO_NRAS_TARGETS_DN | MSigDB lists | CASTELLANO_NRAS_TARGETS_DN | 14 | 5 | 17377 | 2626 |
CYHR1,NRAS,LIMK1,CDKN2A,RBM38 |
| 4.800e-02 | -3.04 | VISALA_RESPONSE_TO_HEAT_SHOCK_AND_AGING_UP | MSigDB lists | VISALA_RESPONSE_TO_HEAT_SHOCK_AND_AGING_UP | 14 | 5 | 17377 | 2626 |
ST13,DHPS,GRSF1,NDUFS4,FDFT1 |
| 4.800e-02 | -3.04 | GO_REGULATION_OF_PROTEIN_LOCALIZATION_TO_CHROMOSOME_TELOMERIC_REGION | MSigDB lists | GO_REGULATION_OF_PROTEIN_LOCALIZATION_TO_CHROMOSOME_TELOMERIC_REGION | 14 | 5 | 17377 | 2626 |
H2AFY,CCT2,TERF1,CCT8,PML |
| 4.800e-02 | -3.04 | GO_CARDIOLIPIN_METABOLIC_PROCESS | MSigDB lists | GO_CARDIOLIPIN_METABOLIC_PROCESS | 14 | 5 | 17377 | 2626 |
TAZ,LCLAT1,PGS1,MECP2,HADHB |
| 4.800e-02 | -3.04 | GO_PROTEIN_TARGETING_TO_LYSOSOME | MSigDB lists | GO_PROTEIN_TARGETING_TO_LYSOSOME | 14 | 5 | 17377 | 2626 |
NAGPA,SCARB2,GCC2,HGS,RAB7A |
| 4.800e-02 | -3.04 | GO_CONTRACTILE_ACTIN_FILAMENT_BUNDLE_ASSEMBLY | MSigDB lists | GO_CONTRACTILE_ACTIN_FILAMENT_BUNDLE_ASSEMBLY | 14 | 5 | 17377 | 2626 |
PDCD10,RHOA,ITGB5,ITGB1,CUL3 |
| 4.800e-02 | -3.04 | MODULE_147 | MSigDB lists | MODULE_147 | 107 | 23 | 17377 | 2626 |
TGFB1,RPLP2,NCK1,EID1,MECP2,OXR1,TMEM97,NUP54,CRNKL1,CDC42SE2,SLC20A1,LYN,SLC25A37,RXRB,TRIM4,PSMD2,CLIC4,TXNDC16,PFDN4,DBNDD1,EFTUD2,PPP4R1,H3F3A |
| 4.804e-02 | -3.04 | unconventional myosin complex | cellular component | GO:0016461 | 10 | 4 | 18223 | 2701 |
MYO9A,MYL6B,MYO5A,MYO1F |
| 4.804e-02 | -3.04 | X chromosome | cellular component | GO:0000805 | 10 | 4 | 18223 | 2701 |
H2AFY,H2AFZ,H3F3A,CDK2 |
| 4.804e-02 | -3.04 | endoplasmic reticulum chaperone complex | cellular component | GO:0034663 | 10 | 4 | 18223 | 2701 |
PPIB,DNAJC10,SDF2L1,PDIA6 |
| 4.804e-02 | -3.04 | VCP-NPL4-UFD1 AAA ATPase complex | cellular component | GO:0034098 | 10 | 4 | 18223 | 2701 |
DERL1,FAF1,NPLOC4,UBXN1 |
| 4.804e-02 | -3.04 | nuclear pore outer ring | cellular component | GO:0031080 | 10 | 4 | 18223 | 2701 |
AHCTF1,NUP85,SEH1L,NUP107 |
| 4.810e-02 | -3.03 | TRAPPC12 (trafficking protein particle complex 12) | protein interactions | 51112 | 26 | 8 | 17029 | 2761 |
TRAPPC13,TRAPPC9,TBC1D14,CEP55,PTAR1,SIRT2,RAB1A,EDRF1 |
| 4.810e-02 | -3.03 | DIS3L (DIS3 like exosome 3'-5' exoribonuclease) | protein interactions | 115752 | 26 | 8 | 17029 | 2761 |
LIN9,EXOSC9,EXOSC6,EXOSC7,SNRNP70,ZNF598,EXOSC1,H2AFX |
| 4.810e-02 | -3.03 | RAD51C (RAD51 paralog C) | protein interactions | 5889 | 26 | 8 | 17029 | 2761 |
CBWD1,XRCC3,TGOLN2,IL12RB1,PALB2,APP,RAD51D,XRCC2 |
| 4.810e-02 | -3.03 | Ubr5 (ubiquitin protein ligase E3 component n-recognin 5) | protein interactions | 70790 | 26 | 8 | 17029 | 2761 |
EIF3L,DDX28,WDR91,DPM1,PARK7,NOL8,KCNAB2,RRM1 |
| 4.810e-02 | -3.03 | CSTB (cystatin B) | protein interactions | 1476 | 26 | 8 | 17029 | 2761 |
CTSL,SARNP,PDCD6,VHL,CUL3,MCM2,MAT2A,NUDC |
| 4.810e-02 | -3.03 | C7orf50 (chromosome 7 open reading frame 50) | protein interactions | 84310 | 26 | 8 | 17029 | 2761 |
RPA2,CYLD,RPL8,CUL1,APP,PRNP,CAND1,RPA1 |
| 4.810e-02 | -3.03 | MAN2A2 (mannosidase alpha class 2A member 2) | protein interactions | 4122 | 26 | 8 | 17029 | 2761 |
CAPN2,GALNT7,TAZ,CHD3,HLA-E,FUT8,LUC7L2,PTPRK |
| 4.810e-02 | -3.03 | OAZ1 (ornithine decarboxylase antizyme 1) | protein interactions | 4946 | 26 | 8 | 17029 | 2761 |
UPF1,RAB7A,OAZ2,ATXN1,SMAD1,ODC1,OAZ1,GPATCH4 |
| 4.810e-02 | -3.03 | KDELR1 (KDEL endoplasmic reticulum protein retention receptor 1) | protein interactions | 10945 | 26 | 8 | 17029 | 2761 |
UBQLN4,TRAFD1,ARF1,NEK6,MCM2,UCHL5,NPLOC4,KDELR1 |
| 4.810e-02 | -3.03 | DCAF16 (DDB1 and CUL4 associated factor 16) | protein interactions | 54876 | 26 | 8 | 17029 | 2761 |
CSNK1G2,TRIM41,TULP3,DDA1,RBPJ,COPS6,DDB1,DEF6 |
| 4.810e-02 | -3.03 | PDP1 (pyruvate dehyrogenase phosphatase catalytic subunit 1) | protein interactions | 54704 | 26 | 8 | 17029 | 2761 |
SAMD4B,SNUPN,WDR44,CORO1C,ACAT1,CBFA2T2,SDHA,SPTAN1 |
| 4.810e-02 | -3.03 | MTHFD1L (methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like) | protein interactions | 25902 | 26 | 8 | 17029 | 2761 |
HGS,CYLD,MAGED1,LRPPRC,CUL3,ADRB2,TAGLN2,PAPOLA |
| 4.810e-02 | -3.03 | RIOK3 (RIO kinase 3) | protein interactions | 8780 | 26 | 8 | 17029 | 2761 |
CDC42,TM9SF4,XRCC3,RUVBL2,FBL,SMURF1,ZMAT3,PSMC4 |
| 4.810e-02 | -3.03 | TGM3 (transglutaminase 3) | protein interactions | 7053 | 26 | 8 | 17029 | 2761 |
PRKAB1,CYLD,UCHL5,MCM5,PPME1,MCM2,USP53,WWP2 |
| 4.810e-02 | -3.03 | PMVK (phosphomevalonate kinase) | protein interactions | 10654 | 26 | 8 | 17029 | 2761 |
FYTTD1,PITPNA,MCPH1,SDHA,SETD3,ARL6IP6,NKD2,TBPL1 |
| 4.810e-02 | -3.03 | CDIPT (CDP-diacylglycerol--inositol 3-phosphatidyltransferase) | protein interactions | 10423 | 26 | 8 | 17029 | 2761 |
STAU1,PTPN18,RPLP1,CAPZA2,ORC1,APP,RTN3,SMAP2 |
| 4.810e-02 | -3.03 | CHTF18 (chromosome transmission fidelity factor 18) | protein interactions | 63922 | 26 | 8 | 17029 | 2761 |
RPA2,PCNA,HSPA4,RFC3,XRCC3,STAT3,RFC2,RPA1 |
| 4.810e-02 | -3.03 | Fbl (fibrillarin) | protein interactions | 14113 | 26 | 8 | 17029 | 2761 |
COPS8,SLCO4A1,MRPS2,DNAJA1,BECN1,ABCF1,COIL,IFI16 |
| 4.810e-02 | -3.03 | Plk1 (polo like kinase 1) | protein interactions | 18817 | 26 | 8 | 17029 | 2761 |
PLK1,RANGAP1,BICD2,BORA,SPAG5,NSUN2,HAUS8,PRC1 |
| 4.810e-02 | -3.03 | ADAM21 (ADAM metallopeptidase domain 21) | protein interactions | 8747 | 26 | 8 | 17029 | 2761 |
HLA-B,DHFR2,ITGB5,LCLAT1,GNB2,ANKRD46,PDF,ASPHD2 |
| 4.810e-02 | -3.03 | RPP25L (ribonuclease P/MRP subunit p25 like) | protein interactions | 138716 | 26 | 8 | 17029 | 2761 |
PLK1,ARHGEF2,KRAS,NPHP4,MPHOSPH8,RBM4,POP7,CUL3 |
| 4.810e-02 | -3.03 | EFL1 (elongation factor like GTPase 1) | protein interactions | 79631 | 26 | 8 | 17029 | 2761 |
RANGAP1,TPD52L2,TP53RK,SASS6,RPRD1B,ABCF2,NSUN2,PCGF6 |
| 4.810e-02 | -3.03 | TCF25 (transcription factor 25) | protein interactions | 22980 | 26 | 8 | 17029 | 2761 |
DERL1,PPAN,USP7,RPS2,DCAF5,AMD1,RPS10,XIAP |
| 4.814e-02 | -3.03 | DNA polymerase activity | molecular function | GO:0034061 | 37 | 10 | 17224 | 2647 |
POLA2,POLE,PRIM2,POLK,PTGES3,POLG2,TERF1,NEXMIF,TERF2,POLQ |
| 4.817e-02 | -3.03 | PTN (pleiotrophin) | protein interactions | 5764 | 100 | 23 | 17029 | 2761 |
BCCIP,FTL,UBQLN4,TOMM20,GADD45G,TBRG4,BCL2L1,RIT1,PMF1,UTP3,SUPT7L,SSR1,GTF2F1,SLC25A36,PPP2CA,RBM23,PSMD2,NEK6,CHD3,RPLP1,ACTB,TP53BP2,LUC7L2 |
| 4.824e-02 | -3.03 | BRUINS_UVC_RESPONSE_MIDDLE | MSigDB lists | BRUINS_UVC_RESPONSE_MIDDLE | 85 | 19 | 17377 | 2626 |
ELOVL5,ZFP64,TP53RK,CASP6,BTG2,SLC25A12,ZFYVE21,CMTM6,SAC3D1,FBRS,FASTKD3,CLUAP1,TMEM41A,NSMCE2,DUSP11,SPRYD4,DEF6,MSH6,SAP30 |
| 4.824e-02 | -3.03 | KYNG_DNA_DAMAGE_BY_GAMMA_AND_UV_RADIATION | MSigDB lists | KYNG_DNA_DAMAGE_BY_GAMMA_AND_UV_RADIATION | 85 | 19 | 17377 | 2626 |
CCNC,PPP3CA,NDUFB6,HEXB,ATP6V0A1,ADSL,DNAJA1,RAB6A,CSNK1A1,EML4,COPB2,POLR2A,CCNA2,RBL1,SIAH1,PPME1,AHCY,MAST2,ALDH9A1 |
| 4.824e-02 | -3.03 | GGCCAGT,MIR-193A,MIR-193B | MSigDB lists | GGCCAGT,MIR-193A,MIR-193B | 85 | 19 | 17377 | 2626 |
MAX,MKLN1,LUZP1,CELSR2,BAZ2A,LRRC8A,MCL1,ARHGEF12,STX16,STMN1,CCDC28A,PTPRF,PTEN,ARPC5,SIAH1,ETV6,YWHAZ,CNOT6,SCYL3 |
| 4.824e-02 | -3.03 | TIEN_INTESTINE_PROBIOTICS_2HR_DN | MSigDB lists | TIEN_INTESTINE_PROBIOTICS_2HR_DN | 85 | 19 | 17377 | 2626 |
RECQL,NCK1,RAF1,MAP4K4,ATP2C1,CIRBP,KLC1,PLXNA1,CADM1,TMEM165,PDHX,PICALM,RDH11,TNS3,GOLGA7,PPP4R1,LRPPRC,UBE3B,CLU |
| 4.824e-02 | -3.03 | GO_ENERGY_COUPLED_PROTON_TRANSPORT_DOWN_ELECTROCHEMICAL_GRADIENT | MSigDB lists | GO_ENERGY_COUPLED_PROTON_TRANSPORT_DOWN_ELECTROCHEMICAL_GRADIENT | 6 | 3 | 17377 | 2626 |
ATP6V0A1,ATP6V0A2,STOML2 |
| 4.824e-02 | -3.03 | BUSA_SAM68_TARGETS_DN | MSigDB lists | BUSA_SAM68_TARGETS_DN | 6 | 3 | 17377 | 2626 |
BRCA1,CLU,CDK2 |
| 4.824e-02 | -3.03 | YANAGISAWA_LUNG_CANCER_RECURRENCE | MSigDB lists | YANAGISAWA_LUNG_CANCER_RECURRENCE | 6 | 3 | 17377 | 2626 |
FAU,ACYP1,S100A6 |
| 4.824e-02 | -3.03 | DING_LUNG_CANCER_MUTATED_RECURRENTLY | MSigDB lists | DING_LUNG_CANCER_MUTATED_RECURRENTLY | 6 | 3 | 17377 | 2626 |
KRAS,STK11,NRAS |
| 4.824e-02 | -3.03 | PALOMERO_GSI_SENSITIVITY_UP | MSigDB lists | PALOMERO_GSI_SENSITIVITY_UP | 6 | 3 | 17377 | 2626 |
PTEN,PHTF1,PIAS2 |
| 4.824e-02 | -3.03 | KAUFFMANN_MELANOMA_RELAPSE_DN | MSigDB lists | KAUFFMANN_MELANOMA_RELAPSE_DN | 6 | 3 | 17377 | 2626 |
CRY2,N4BP2,TERF2 |
| 4.824e-02 | -3.03 | DARWICHE_PAPILLOMA_RISK_HIGH_VS_LOW_UP | MSigDB lists | DARWICHE_PAPILLOMA_RISK_HIGH_VS_LOW_UP | 6 | 3 | 17377 | 2626 |
GLT8D1,VHL,EML4 |
| 4.824e-02 | -3.03 | CHESLER_BRAIN_QTL_TRANS | MSigDB lists | CHESLER_BRAIN_QTL_TRANS | 6 | 3 | 17377 | 2626 |
MYH9,PITPNB,TSPAN5 |
| 4.824e-02 | -3.03 | AGTGCGT,MIR-521 | MSigDB lists | AGTGCGT,MIR-521 | 6 | 3 | 17377 | 2626 |
HNRNPA2B1,DNAJC5,NCDN |
| 4.824e-02 | -3.03 | DONATO_CELL_CYCLE_TRETINOIN | MSigDB lists | DONATO_CELL_CYCLE_TRETINOIN | 6 | 3 | 17377 | 2626 |
ABI1,BTG2,TOB1 |
| 4.824e-02 | -3.03 | MIKHAYLOVA_OXIDATIVE_STRESS_RESPONSE_VIA_VHL_DN | MSigDB lists | MIKHAYLOVA_OXIDATIVE_STRESS_RESPONSE_VIA_VHL_DN | 6 | 3 | 17377 | 2626 |
AKR1B1,OAT,PGAM1 |
| 4.824e-02 | -3.03 | GO_ATP_SYNTHESIS_COUPLED_PROTON_TRANSPORT | MSigDB lists | GO_ATP_SYNTHESIS_COUPLED_PROTON_TRANSPORT | 6 | 3 | 17377 | 2626 |
ATP6V0A1,ATP6V0A2,STOML2 |
| 4.825e-02 | -3.03 | RHO | prosite domains | PS51420 | 20 | 6 | 12060 | 1670 |
RHOG,RHOA,CDC42,RHOC,RHOB,RAC1 |
| 4.826e-02 | -3.03 | positive regulation of plasma membrane bounded cell projection assembly | biological process | GO:0120034 | 90 | 20 | 17256 | 2622 |
WASF2,CYFIP1,SEPT9,AGRN,RAC1,KCTD17,NCKAP1,SEPT7,DOCK11,ANLN,MIEN1,TWF2,DPYSL3,CCP110,CDC42,CENPJ,DNM2,ARAP1,HRAS,ATMIN |
| 4.831e-02 | -3.03 | - | gene3d domains | 2.40.100.10 | 22 | 7 | 8148 | 1295 |
PPIF,PPIB,PPWD1,CWC27,PPIG,PPIE,PPIL2 |
| 4.831e-02 | -3.03 | Iron uptake and transport | REACTOME pathways | R-HSA-917937 | 44 | 12 | 10287 | 1696 |
FTL,ATP6V0B,ATP6V1D,ATP6V0A1,ATP6V0A2,ATP6V0C,ATP6V1B2,ATP6V1C1,ATP6V0D1,ATP6V0E1,TFRC,ATP6V1G1 |
| 4.833e-02 | -3.03 | GSE20500_CTRL_VS_RETINOIC_ACID_TREATED_CD4_TCELL_DN | MSigDB lists | GSE20500_CTRL_VS_RETINOIC_ACID_TREATED_CD4_TCELL_DN | 181 | 36 | 17377 | 2626 |
POMP,SEC16A,PABPC4,GTF2F1,FBRS,CD59,ATP2A2,ZKSCAN1,AKAP8,DCP1A,F2R,STAT3,S100A6,PPIF,YTHDC1,RHOBTB3,RB1CC1,PFKFB3,TOPORS,ICAM2,ELK1,RAB22A,DOT1L,FAS,PI4K2A,SH3BP5,GOLGA2,CSNK1G1,FTSJ1,PPP1R11,AEN,CENPT,PLOD3,HIPK3,ZMAT3,CBX4 |
| 4.833e-02 | -3.03 | GSE7852_TREG_VS_TCONV_DN | MSigDB lists | GSE7852_TREG_VS_TCONV_DN | 181 | 36 | 17377 | 2626 |
SLC12A7,PRPF38B,ANKRD13D,GPBP1L1,DAP,ARID5A,KLF13,SLC20A1,ITGB5,SIAH1,RINL,PTPN11,ATP6V0A2,PCYT2,RNF19A,METTL9,TTLL12,CTDSP2,ORAI2,TSPYL4,EMB,MAP4K4,ICAM2,TANC1,PDE3B,SMAP2,EPB41,PEX5,GRIPAP1,APPL2,MBOAT1,GALNT10,PPP6R3,CLN3,LONP2,CBX4 |
| 4.833e-02 | -3.03 | GSE8621_UNSTIM_VS_LPS_PRIMED_UNSTIM_MACROPHAGE_UP | MSigDB lists | GSE8621_UNSTIM_VS_LPS_PRIMED_UNSTIM_MACROPHAGE_UP | 181 | 36 | 17377 | 2626 |
TMEM106C,C9orf78,TP53RK,TMUB1,MTX3,TMBIM4,TCF3,ENSA,MAPK14,IL21R,PITHD1,RTKN,ZNF428,SEC11A,CTNNBL1,CNPY4,ECD,MRPL11,NAA35,N4BP2,TMBIM1,PCBP2,SLC25A1,CDC5L,NTPCR,LONRF3,METTL5,STOML2,CXXC4,TBC1D17,PKD2,PDXK,CLU,C11orf1,CDK2,GPATCH4 |
| 4.833e-02 | -3.03 | GSE21063_3H_VS_16H_ANTI_IGM_STIM_BCELL_UP | MSigDB lists | GSE21063_3H_VS_16H_ANTI_IGM_STIM_BCELL_UP | 181 | 36 | 17377 | 2626 |
ZCCHC9,TSC22D3,RCOR3,KTN1,MED10,CDKN1B,TARDBP,METTL9,MTX2,ABCC1,AMPD2,NIPAL3,SRSF11,SRP72,ZNF524,TNFAIP3,POLK,PPT1,PARP4,ATP6V0A1,UTP3,CYFIP2,RPL27A,KIF11,GOSR1,PATL1,MYO1F,OPTN,ZC3H7B,MAP4,LY75,GALNT10,TRAF5,ARRB2,TERF1,SMNDC1 |
| 4.833e-02 | -3.03 | GSE46242_CTRL_VS_EGR2_DELETED_TH1_CD4_TCELL_UP | MSigDB lists | GSE46242_CTRL_VS_EGR2_DELETED_TH1_CD4_TCELL_UP | 181 | 36 | 17377 | 2626 |
TRIP10,PHB2,GGA1,UQCR10,OLA1,STARD7,AGPAT1,PCSK7,HMGN3,SND1,MAD2L2,PIP5K1C,MEGF8,ARHGEF2,DCP1A,CENPM,MGAT5,NAGPA,ABHD2,PRRC2A,KIAA0040,ABCF2,VDAC2,SHCBP1,PSMB3,EIF3K,PON2,GRIPAP1,CHD3,NLRC5,BCL7C,BAZ1B,CHMP4B,ASNA1,PPP5C,LRP8 |
| 4.844e-02 | -3.03 | GSE37605_TREG_VS_TCONV_NOD_FOXP3_FUSION_GFP_DN | MSigDB lists | GSE37605_TREG_VS_TCONV_NOD_FOXP3_FUSION_GFP_DN | 158 | 32 | 17377 | 2626 |
RMND5A,NXT1,RPRD1A,MRPL42,MAPKAPK3,DYNLL1,MRI1,MCL1,GMCL1,MAN2B1,LANCL1,DCUN1D5,EIF1B,EIF4G2,RMI1,ABHD14A,RHBDF2,FBXO22,PAIP2,CFLAR,HOMER1,EPRS,SNX18,GADD45B,WDR76,PTDSS1,LONP2,TOB1,HIGD2A,EEF1D,CSNK1D,STARD3NL |
| 4.844e-02 | -3.03 | androgen receptor binding | molecular function | GO:0050681 | 42 | 11 | 17224 | 2647 |
RB1,ARID5A,PIAS2,SMARCA4,DDX5,BRCA1,NCOA1,PRMT2,KDM3A,RNF14,PARK7 |
| 4.847e-02 | -3.03 | PEX19 (peroxisomal biogenesis factor 19) | protein interactions | 5824 | 121 | 27 | 17029 | 2761 |
B3GALT6,NAT14,PPIB,ASPM,UQCR10,LETMD1,PXMP2,IRF3,RHOT1,EIF1B,OIP5,SMAD2,GALNT2,CMSS1,POLE,TMEM54,HADHB,SLC27A4,UQCRH,ABCD1,KIFAP3,CYC1,MYO5A,CDKN2A,HIGD2A,EGLN1,PTOV1 |
| 4.848e-02 | -3.03 | activation of innate immune response | biological process | GO:0002218 | 244 | 47 | 17256 | 2622 |
DDX58,UBE2D3,CYLD,RAF1,CUL1,IRF3,PRKACA,LYN,PSMD9,BIRC2,PSMD2,CTSS,PSMA6,PSMD1,TANK,MAVS,CNPY3,PDPK1,NRAS,TNFAIP3,BIRC3,CGAS,MAPKAPK3,PSMA8,PRKDC,PSPC1,PSMB7,PSMA1,UBE2V1,KRAS,ICAM2,PSMB9,MATR3,PSMB3,FADD,PSMC4,XRCC5,CTSL,TAB2,RPS27A,PSMD8,PSMD3,PQBP1,TICAM1,HRAS,PSMC1,IFI16 |
| 4.863e-02 | -3.02 | GKCGCNNNNNNNTGAYG_UNKNOWN | MSigDB lists | GKCGCNNNNNNNTGAYG_UNKNOWN | 53 | 13 | 17377 | 2626 |
BRMS1,PHF20L1,NEK1,CCDC86,ZNF367,RNPS1,MECR,NUP155,NUP153,ADPGK,UBE4A,FAU,MFN2 |
| 4.863e-02 | -3.02 | CTCTAGA,MIR-526C,MIR-518F,MIR-526A | MSigDB lists | CTCTAGA,MIR-526C,MIR-518F,MIR-526A | 53 | 13 | 17377 | 2626 |
HMGN1,MLEC,HNRNPR,CS,RBM3,FAM126A,ARGLU1,SRSF5,H3F3A,SLTM,CBX4,SLC25A33,FBRS |
| 4.863e-02 | -3.02 | chr5q13 | MSigDB lists | chr5q13 | 53 | 13 | 17377 | 2626 |
ZBED3,NSA2,SERF1B,AGGF1,POLK,HEXB,MRPS27,UTP15,BTF3,CCDC125,F2R,GFM2,POC5 |
| 4.863e-02 | -3.02 | BIOCARTA_NFAT_PATHWAY | MSigDB lists | BIOCARTA_NFAT_PATHWAY | 53 | 13 | 17377 | 2626 |
CALM2,FKBP1A,PPP3CA,NFATC3,RAF1,PRKAR1B,NFATC2,PPP3CB,CSNK1A1,MAPK14,MAPK1,HRAS,MAPK3 |
| 4.865e-02 | -3.02 | clear_cell_papillary_renal_cell_carcinoma | COSMIC cancer mutations | clear_cell_papillary_renal_cell_carcinoma | 10 | 4 | 17385 | 2587 |
KRAS,NRAS,PTEN,VHL |
| 4.865e-02 | -3.02 | central_nervous_system-parietooccipital-glioma-oligodendroglioma_Grade_II | COSMIC cancer mutations | central_nervous_system-parietooccipital-glioma-oligodendroglioma_Grade_II | 10 | 4 | 17385 | 2587 |
CDKN2C,H3F3A,NF1,PTEN |
| 4.865e-02 | -3.02 | upper_aerodigestive_tract-sinonasal_and_nasal_cavity-carcinoma-adenocarcinoma | COSMIC cancer mutations | upper_aerodigestive_tract-sinonasal_and_nasal_cavity-carcinoma-adenocarcinoma | 10 | 4 | 17385 | 2587 |
KRAS,NRAS,HRAS,CDKN2A |
| 4.865e-02 | -3.02 | central_nervous_system-frontal_lobe-glioma-astrocytoma_Grade_III | COSMIC cancer mutations | central_nervous_system-frontal_lobe-glioma-astrocytoma_Grade_III | 10 | 4 | 17385 | 2587 |
KRAS,H3F3A,PTEN,CDKN2A |
| 4.865e-02 | -3.02 | epithelioid_sarcoma | COSMIC cancer mutations | epithelioid_sarcoma | 10 | 4 | 17385 | 2587 |
KRAS,EWSR1,NRAS,HRAS |
| 4.865e-02 | -3.02 | soft_tissue-fibrous_tissue_and_uncertain_origin-epithelioid_sarcoma | COSMIC cancer mutations | soft_tissue-fibrous_tissue_and_uncertain_origin-epithelioid_sarcoma | 10 | 4 | 17385 | 2587 |
KRAS,EWSR1,NRAS,HRAS |
| 4.865e-02 | -3.02 | large_intestine-left-carcinoma-adenocarcinoma | COSMIC cancer mutations | large_intestine-left-carcinoma-adenocarcinoma | 10 | 4 | 17385 | 2587 |
KRAS,STK11,CDKN2A,MSH2 |
| 4.865e-02 | -3.02 | bone-chondrosarcoma-dedifferentiated | COSMIC cancer mutations | bone-chondrosarcoma-dedifferentiated | 10 | 4 | 17385 | 2587 |
GNAS,EWSR1,NRAS,CDKN2A |
| 4.865e-02 | -3.02 | genital_tract-extragonadal-germ_cell_tumour-non_seminoma | COSMIC cancer mutations | genital_tract-extragonadal-germ_cell_tumour-non_seminoma | 10 | 4 | 17385 | 2587 |
KRAS,NRAS,NF1,PTEN |
| 4.865e-02 | -3.02 | stomach-carcinoid-endocrine_tumour | COSMIC cancer mutations | stomach-carcinoid-endocrine_tumour | 10 | 4 | 17385 | 2587 |
KRAS,MEN1,PTEN,CDKN2A |
| 4.865e-02 | -3.02 | elbow | COSMIC cancer mutations | elbow | 10 | 4 | 17385 | 2587 |
KRAS,NRAS,HRAS,CDKN2A |
| 4.865e-02 | -3.02 | kidney-carcinoma-clear_cell_papillary_renal_cell_carcinoma | COSMIC cancer mutations | kidney-carcinoma-clear_cell_papillary_renal_cell_carcinoma | 10 | 4 | 17385 | 2587 |
KRAS,NRAS,PTEN,VHL |
| 4.865e-02 | -3.02 | skin-back-malignant_melanoma-nodular | COSMIC cancer mutations | skin-back-malignant_melanoma-nodular | 10 | 4 | 17385 | 2587 |
KRAS,NRAS,HRAS,CDKN2A |
| 4.881e-02 | -3.02 | Lactose Synthesis | SMPDB pathways | SMP00444 | 9 | 4 | 992 | 167 |
CANT1,B4GALT1,UGP2,SLC2A1 |
| 4.881e-02 | -3.02 | Congenital disorder of glycosylation CDG-IId | SMPDB pathways | SMP00579 | 9 | 4 | 992 | 167 |
B4GALT1,CANT1,UGP2,SLC2A1 |
| 4.881e-02 | -3.02 | GLUT-1 deficiency syndrome | SMPDB pathways | SMP00580 | 9 | 4 | 992 | 167 |
CANT1,B4GALT1,UGP2,SLC2A1 |
| 4.887e-02 | -3.02 | RB_P107_DN.V1_DN | MSigDB lists | RB_P107_DN.V1_DN | 124 | 26 | 17377 | 2626 |
PLK3,BCCIP,SIGMAR1,DYNLL1,RNF25,NSUN2,RBM8A,MOGS,POMP,LACTB2,TARS,BSDC1,KIAA1147,RDH11,PDCD6,IARS,DAD1,STAT6,BDH1,UBA5,SRI,PPA2,UBE3B,NRBP1,HIGD2A,NIPSNAP1 |
| 4.893e-02 | -3.02 | PDGF_ERK_DN.V1_DN | MSigDB lists | PDGF_ERK_DN.V1_DN | 141 | 29 | 17377 | 2626 |
TMEM115,KLF10,ZNF500,ERF,CIC,ZNF202,CDK2AP2,MOGS,MON1B,FRAT2,FAM50B,DNAJB1,SLC25A44,CCNF,POLG2,MBD3,SNAPC4,RHOB,DNAJB9,FADD,MAPK3,SAC3D1,KDM2A,NFIL3,FAM89B,CDKN1B,PPP6R1,RNF139,MORC3 |
| 4.893e-02 | -3.02 | BROCKE_APOPTOSIS_REVERSED_BY_IL6 | MSigDB lists | BROCKE_APOPTOSIS_REVERSED_BY_IL6 | 141 | 29 | 17377 | 2626 |
POU2AF1,CCNC,IER2,TMED7,RHOBTB3,TMEM184B,DPM1,ELL2,FLOT1,PTP4A3,MCL1,STK17B,FOXO3,PNO1,DNAJB9,IRF4,RB1,DUSP3,IL6ST,GADD45B,FAM3C,STAT1,LPCAT4,PTPN11,DAPK1,EIF5,STAT3,ZBTB11,SRPK2 |
| 4.894e-02 | -3.02 | negative regulation of cell cycle checkpoint | biological process | GO:1901977 | 6 | 3 | 17256 | 2622 |
CHEK2,THOC1,CDT1 |
| 4.894e-02 | -3.02 | microtubule nucleation by interphase microtubule organizing center | biological process | GO:0051415 | 6 | 3 | 17256 | 2622 |
MZT1,TUBGCP2,TUBGCP5 |
| 4.894e-02 | -3.02 | 'de novo' IMP biosynthetic process | biological process | GO:0006189 | 6 | 3 | 17256 | 2622 |
ADSL,GART,ATIC |
| 4.894e-02 | -3.02 | cardiolipin acyl-chain remodeling | biological process | GO:0035965 | 6 | 3 | 17256 | 2622 |
TAZ,LCLAT1,HADHB |
| 4.894e-02 | -3.02 | succinyl-CoA metabolic process | biological process | GO:0006104 | 6 | 3 | 17256 | 2622 |
SUCLG2,OGDH,SUCLG1 |
| 4.894e-02 | -3.02 | regulation of isotype switching to IgA isotypes | biological process | GO:0048296 | 6 | 3 | 17256 | 2622 |
TGFB1,THOC1,MSH2 |
| 4.894e-02 | -3.02 | pyrimidine deoxyribonucleoside monophosphate biosynthetic process | biological process | GO:0009177 | 6 | 3 | 17256 | 2622 |
DCTD,DUT,HDDC2 |
| 4.894e-02 | -3.02 | positive regulation of DNA-directed DNA polymerase activity | biological process | GO:1900264 | 6 | 3 | 17256 | 2622 |
RFC3,RFC2,CHTF18 |
| 4.894e-02 | -3.02 | lamellipodium morphogenesis | biological process | GO:0072673 | 6 | 3 | 17256 | 2622 |
WASF2,SNX2,ABI1 |
| 4.894e-02 | -3.02 | protein ufmylation | biological process | GO:0071569 | 6 | 3 | 17256 | 2622 |
UBA5,UFC1,DDRGK1 |
| 4.894e-02 | -3.02 | spindle assembly involved in meiosis | biological process | GO:0090306 | 6 | 3 | 17256 | 2622 |
GOLGA2,ASPM,FBXO5 |
| 4.894e-02 | -3.02 | negative regulation of epithelial cell proliferation involved in prostate gland development | biological process | GO:0060770 | 6 | 3 | 17256 | 2622 |
CDKN1B,STK11,EAF2 |
| 4.894e-02 | -3.02 | common-partner SMAD protein phosphorylation | biological process | GO:0007182 | 6 | 3 | 17256 | 2622 |
TGFB1,SMAD2,PML |
| 4.894e-02 | -3.02 | ganglioside catabolic process | biological process | GO:0006689 | 6 | 3 | 17256 | 2622 |
GM2A,NEU1,HEXB |
| 4.894e-02 | -3.02 | positive regulation of MHC class I biosynthetic process | biological process | GO:0045345 | 6 | 3 | 17256 | 2622 |
HSPH1,NLRC5,PML |
| 4.894e-02 | -3.02 | positive regulation of xenophagy | biological process | GO:1904417 | 6 | 3 | 17256 | 2622 |
LRSAM1,OPTN,MAPK3 |
| 4.894e-02 | -3.02 | regulation of Fc receptor mediated stimulatory signaling pathway | biological process | GO:0060368 | 6 | 3 | 17256 | 2622 |
RAP1A,LYN,CSK |
| 4.894e-02 | -3.02 | neuron projection maintenance | biological process | GO:1990535 | 6 | 3 | 17256 | 2622 |
PSEN1,APP,PRNP |
| 4.894e-02 | -3.02 | negative regulation of mitophagy | biological process | GO:1901525 | 6 | 3 | 17256 | 2622 |
TSC2,TIGAR,HTRA2 |
| 4.894e-02 | -3.02 | pH elevation | biological process | GO:0045852 | 6 | 3 | 17256 | 2622 |
BCL2,CLN3,SLC26A6 |
| 4.894e-02 | -3.02 | dUMP metabolic process | biological process | GO:0046078 | 6 | 3 | 17256 | 2622 |
DCTD,DUT,HDDC2 |
| 4.894e-02 | -3.02 | pyrimidine nucleotide salvage | biological process | GO:0032262 | 6 | 3 | 17256 | 2622 |
UCK1,HDDC2,UCK2 |
| 4.894e-02 | -3.02 | regulation of DNA-directed DNA polymerase activity | biological process | GO:1900262 | 6 | 3 | 17256 | 2622 |
RFC3,RFC2,CHTF18 |
| 4.894e-02 | -3.02 | regulation of xenophagy | biological process | GO:1904415 | 6 | 3 | 17256 | 2622 |
LRSAM1,OPTN,MAPK3 |
| 4.894e-02 | -3.02 | regulation of androgen receptor activity | biological process | GO:2000823 | 6 | 3 | 17256 | 2622 |
RWDD1,PARK7,BUD31 |
| 4.894e-02 | -3.02 | locomotion involved in locomotory behavior | biological process | GO:0031987 | 6 | 3 | 17256 | 2622 |
PPP3CB,CLN6,MYO5A |
| 4.894e-02 | -3.02 | positive regulation of cytokine secretion involved in immune response | biological process | GO:0002741 | 6 | 3 | 17256 | 2622 |
KARS,MAPK14,MAPK3 |
| 4.894e-02 | -3.02 | intracellular pH elevation | biological process | GO:0051454 | 6 | 3 | 17256 | 2622 |
BCL2,CLN3,SLC26A6 |
| 4.894e-02 | -3.02 | histone H4-K20 trimethylation | biological process | GO:0034773 | 6 | 3 | 17256 | 2622 |
BEND3,KMT5C,ARID4A |
| 4.894e-02 | -3.02 | regulation of microtubule nucleation | biological process | GO:0010968 | 6 | 3 | 17256 | 2622 |
MECP2,DCTN1,HSPA1B |
| 4.894e-02 | -3.02 | histone dephosphorylation | biological process | GO:0016576 | 6 | 3 | 17256 | 2622 |
PPP5C,EYA2,EYA1 |
| 4.897e-02 | -3.02 | ANK_REP_REGION | prosite domains | PS50297 | 242 | 43 | 12060 | 1670 |
MIB2,ANKRD27,MPHOSPH8,PPP1R12A,YTHDC2,ANK3,ACAP1,NOTCH2,PPP1R16B,GIT2,ANKIB1,ANKRD23,ANKRD39,ANKRD28,ANKRD26,CDKN2C,ANKLE1,ASAP2,ZDHHC13,PPP1R12C,DAPK1,FEM1B,OSTF1,ANKRD13C,TP53BP2,ANKHD1,ASB6,ANKRD9,MTPN,ANKRD37,ANKRD33B,EHMT1,RFXANK,TANC1,ASB13,ANKRD46,KRIT1,ANKZF1,ANKRD10,TONSL,RNASEL,SLF1,CDKN2A |
| 4.899e-02 | -3.02 | protein localization to chromosome, telomeric region | biological process | GO:0070198 | 14 | 5 | 17256 | 2622 |
TERF2IP,POT1,TERF2,NABP2,XRCC5 |
| 4.899e-02 | -3.02 | positive regulation of metallopeptidase activity | biological process | GO:1905050 | 14 | 5 | 17256 | 2622 |
KARS,STAT3,MAPK14,MAPK3,DDRGK1 |
| 4.899e-02 | -3.02 | glycolipid catabolic process | biological process | GO:0019377 | 14 | 5 | 17256 | 2622 |
GALC,GM2A,NEU1,HEXB,GBA |
| 4.899e-02 | -3.02 | mitochondrial electron transport, ubiquinol to cytochrome c | biological process | GO:0006122 | 14 | 5 | 17256 | 2622 |
UQCRH,CYCS,CYC1,UQCR10,MECP2 |
| 4.899e-02 | -3.02 | tRNA wobble uridine modification | biological process | GO:0002098 | 14 | 5 | 17256 | 2622 |
GTPBP3,ELP4,CTU2,ELP5,TRMU |
| 4.899e-02 | -3.02 | endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) | biological process | GO:0000479 | 14 | 5 | 17256 | 2622 |
KRI1,UTP20,BMS1,RRS1,RPSA |
| 4.899e-02 | -3.02 | S-adenosylmethionine metabolic process | biological process | GO:0046500 | 14 | 5 | 17256 | 2622 |
MAT2B,AHCY,AHCYL1,AMD1,MAT2A |
| 4.899e-02 | -3.02 | cellular response to dopamine | biological process | GO:1903351 | 14 | 5 | 17256 | 2622 |
GABPA,MAPK1,HDAC2,MAPK3,DNM2 |
| 4.899e-02 | -3.02 | proteasome assembly | biological process | GO:0043248 | 14 | 5 | 17256 | 2622 |
PSMG1,POMP,PSMD9,ECPAS,PSMD8 |
| 4.899e-02 | -3.02 | contractile actin filament bundle assembly | biological process | GO:0030038 | 14 | 5 | 17256 | 2622 |
PDCD10,RHOA,ITGB5,ITGB1,CUL3 |
| 4.899e-02 | -3.02 | response to dopamine | biological process | GO:1903350 | 14 | 5 | 17256 | 2622 |
GABPA,MAPK1,HDAC2,MAPK3,DNM2 |
| 4.899e-02 | -3.02 | IMP metabolic process | biological process | GO:0046040 | 14 | 5 | 17256 | 2622 |
AMPD2,ADSL,ADSS,GART,ATIC |
| 4.899e-02 | -3.02 | stress fiber assembly | biological process | GO:0043149 | 14 | 5 | 17256 | 2622 |
PDCD10,RHOA,ITGB5,ITGB1,CUL3 |
| 4.899e-02 | -3.02 | histone H3-K9 modification | biological process | GO:0061647 | 14 | 5 | 17256 | 2622 |
BEND3,SUV39H2,KDM3A,ARID4A,EHMT1 |
| 4.899e-02 | -3.02 | IRF3-mediated induction of type I IFN | REACTOME pathways | R-HSA-3270619 | 13 | 5 | 10287 | 1696 |
IRF3,PRKDC,IFI16,XRCC5,DTX4 |
| 4.899e-02 | -3.02 | Initiation of Nuclear Envelope Reformation | REACTOME pathways | R-HSA-2995383 | 13 | 5 | 10287 | 1696 |
ANKLE2,PPP2CA,LEMD2,BANF1,LMNA |
| 4.899e-02 | -3.02 | SeMet incorporation into proteins | REACTOME pathways | R-HSA-2408517 | 13 | 5 | 10287 | 1696 |
KARS,EPRS,LARS,IARS,QARS |
| 4.899e-02 | -3.02 | AKT phosphorylates targets in the cytosol | REACTOME pathways | R-HSA-198323 | 13 | 5 | 10287 | 1696 |
CDKN1B,MDM2,AKT1S1,TSC2,AKT2 |
| 4.899e-02 | -3.02 | Nuclear Envelope Reassembly | REACTOME pathways | R-HSA-2995410 | 13 | 5 | 10287 | 1696 |
ANKLE2,PPP2CA,LEMD2,BANF1,LMNA |
| 4.899e-02 | -3.02 | Caspase-mediated cleavage of cytoskeletal proteins | REACTOME pathways | R-HSA-264870 | 13 | 5 | 10287 | 1696 |
GAS2,PLEC,ADD1,CASP6,SPTAN1 |
| 4.902e-02 | -3.02 | DNA Damage Response (only ATM dependent) | WikiPathways | WP710 | 114 | 25 | 5312 | 837 |
TGFB1,BAK1,RHOA,NRAS,AKT2,RAC1,KRAS,FOXO3,MAP3K4,CAT,MDM2,CDC42,SHC1,PTEN,WNT5B,AXIN1,PIK3R2,CDKN1B,BCL2,DVL1,MAPK1,HRAS,SMAD4,CDKN2A,DVL2 |
| 4.903e-02 | -3.02 | GSE39110_UNTREATED_VS_IL2_TREATED_CD8_TCELL_DAY3_POST_IMMUNIZATION_UP | MSigDB lists | GSE39110_UNTREATED_VS_IL2_TREATED_CD8_TCELL_DAY3_POST_IMMUNIZATION_UP | 187 | 37 | 17377 | 2626 |
CYTIP,CYLD,CKLF,TSC22D3,DNAJB2,B4GALT1,FOXO3,ABHD14A,BIRC2,APP,HLA-A,CFLAR,TFAP4,PRKD3,PIK3IP1,FTSJ3,RHBDD2,KIAA0040,ZMYND11,KIAA0930,MEF2D,ARID1A,VKORC1,KLF6,TMEM127,CHD3,FAM3C,PITX1,DTX4,DDX5,GALNT10,SMAD1,HEXA,EYA2,SMAD4,CBX4,GPATCH4 |
| 4.903e-02 | -3.02 | GSE19401_UNSTIM_VS_PAM2CSK4_STIM_FOLLICULAR_DC_UP | MSigDB lists | GSE19401_UNSTIM_VS_PAM2CSK4_STIM_FOLLICULAR_DC_UP | 187 | 37 | 17377 | 2626 |
IER2,NCOR2,KARS,NF1,KLHL21,WDR13,DHX8,CHD1,FOXO3,RNF103,MXD1,LRRC14,KRR1,TNFAIP8,ZKSCAN1,LPIN2,TIMELESS,BCL2,BCAP29,CRY2,GLE1,CPSF4,USP34,SRSF10,PLK3,BRD4,RFC3,MKLN1,BMS1,PRPF3,POLG2,HGS,JAK1,H2AFX,XRCC3,TAF6,PURA |
| 4.903e-02 | -3.02 | GSE43955_1H_VS_20H_ACT_CD4_TCELL_DN | MSigDB lists | GSE43955_1H_VS_20H_ACT_CD4_TCELL_DN | 187 | 37 | 17377 | 2626 |
CYTIP,MRPL9,HLA-E,ANKH,PTTG1,DBF4,NUP54,CUL1,MEF2A,GLUD1,SLC20A1,TTF1,SRXN1,PRNP,CTSS,FBXW2,ALDH18A1,GNAI2,TMX1,BRD4,MIOS,KLF10,RAD51AP1,PPIE,FXR1,LY6E,NMT2,DDX17,AHNAK,MTHFD2,KEAP1,WNT5B,LUC7L3,MAPK6,CANT1,FKBP5,FAU |
| 4.903e-02 | -3.02 | GSE7460_CTRL_VS_TGFB_TREATED_ACT_CD8_TCELL_DN | MSigDB lists | GSE7460_CTRL_VS_TGFB_TREATED_ACT_CD8_TCELL_DN | 187 | 37 | 17377 | 2626 |
MAX,GOLIM4,PARP12,ZNF445,ZBTB37,WDR13,ANKH,KIAA0232,TMX4,TRIO,B4GALT4,RGS2,PRNP,MED10,IMPAD1,ZCCHC2,SS18L1,MDFIC,TTC17,TIPARP,TIMP2,COQ10B,PLEKHM3,RAB3IP,CADM1,STX16,MTMR3,TMEM127,GNA12,KPNA4,CERS6,WNT5B,TBPL1,USP32,MYO9A,GLCCI1,ABCA1 |
| 4.903e-02 | -3.02 | GSE21670_STAT3_KO_VS_WT_CD4_TCELL_TGFB_IL6_TREATED_DN | MSigDB lists | GSE21670_STAT3_KO_VS_WT_CD4_TCELL_TGFB_IL6_TREATED_DN | 187 | 37 | 17377 | 2626 |
MANBA,TSC22D3,CCM2,ASAH1,CREBL2,RGS2,GNS,CTSS,SLC44A1,RCSD1,DAPK1,CITED2,RHBDD2,CTDSP2,TMBIM1,SMC4,GPX4,TIMP2,SEPT9,CREG1,NEK7,KIAA0930,TLK1,PARP4,WIPF1,ESYT1,SLC17A5,NMT2,PLD3,AHNAK,TPP2,STK38,GLG1,PSAP,ZMIZ1,ARRB2,ANXA11 |
| 4.903e-02 | -3.02 | GSE3982_MAC_VS_NKCELL_UP | MSigDB lists | GSE3982_MAC_VS_NKCELL_UP | 187 | 37 | 17377 | 2626 |
HIVEP3,COX5B,CMAS,PLXNC1,REPS2,NDUFB6,TOR3A,CDCA8,C2orf49,RAB11A,CMTM6,RGS1,ZNF804A,EIF4A3,PTEN,RAB4A,H2AFY,ANXA5,MYO5A,LDHB,ACP2,MKLN1,HTATIP2,NUSAP1,ASB13,MCFD2,SHCBP1,APPL1,EML4,PRDX3,CCDC6,PGRMC1,USP32,PDXK,RBPJ,PGAM1,NUMB |
| 4.903e-02 | -3.02 | GSE10240_CTRL_VS_IL17_STIM_PRIMARY_BRONCHIAL_EPITHELIAL_CELLS_DN | MSigDB lists | GSE10240_CTRL_VS_IL17_STIM_PRIMARY_BRONCHIAL_EPITHELIAL_CELLS_DN | 187 | 37 | 17377 | 2626 |
SLC12A7,OTUD5,LIME1,TMUB1,CORO7,CTCF,RGS2,USP5,ANKLE1,PDXP,FBXL6,NUP210,EIF4A3,INTS1,F2R,CNPY3,PPP1R18,TRAPPC9,TNFAIP3,PSMB7,RPL38,WBP2,EZR,NFATC2,ICAM2,TOMM40,SYMPK,MAP2K2,POLR2A,TBC1D17,AGPAT2,JAK1,TWSG1,MAFK,FAM83D,ABCA1,AAAS |
| 4.903e-02 | -3.02 | GSE4748_CTRL_VS_CYANOBACTERIUM_LPSLIKE_STIM_DC_1H_DN | MSigDB lists | GSE4748_CTRL_VS_CYANOBACTERIUM_LPSLIKE_STIM_DC_1H_DN | 187 | 37 | 17377 | 2626 |
UBE2D3,TRAK1,AP3M2,PLXNA1,SNN,PRKACA,FBXO22,PAPOLA,NUP210,PTEN,RP2,ST8SIA2,SRSF10,ADCY7,SP3,TDP1,SHOC2,FOXK1,WDR1,NUDT4,ATP2C1,MTMR6,ATP6V0A1,TOR1AIP2,SLC25A22,KCNQ1,SRSF5,FAM50B,IL12RB1,PITPNB,SRSF1,NEK1,E2F4,CAPN7,ZMIZ1,SNAPIN,PRPF4B |
| 4.904e-02 | -3.02 | TGF-beta receptor signaling | Pathway Interaction DB | tgfbrpathway | 51 | 15 | 2226 | 426 |
PDPK1,TGFB1,PPP2CA,FKBP1A,RHOA,SMAD2,SHC1,AXIN1,PML,XIAP,EIF2A,SMURF1,ARRB2,SMAD4,STRAP |
| 4.906e-02 | -3.01 | UBE2Z (ubiquitin conjugating enzyme E2 Z) | protein interactions | 65264 | 40 | 11 | 17029 | 2761 |
MDM2,UBR2,LNX2,SYVN1,SMAD1,TRIM65,SMAD4,RNF139,RNF5,PLEKHF2,RNF103 |
| 4.906e-02 | -3.01 | GDPD5 (glycerophosphodiester phosphodiesterase domain containing 5) | protein interactions | 81544 | 40 | 11 | 17029 | 2761 |
LEMD2,ZDHHC18,NDC1,GOLIM4,PEX5,SIAH1,PIGQ,TYW1,SCAMP4,GPR89B,NDUFS4 |
| 4.906e-02 | -3.01 | Cct3 (chaperonin containing Tcp1, subunit 3 (gamma)) | protein interactions | 12462 | 40 | 11 | 17029 | 2761 |
CCT2,PDCD6,PTEN,IGBP1,CCT8,GNB2,GFM2,PDCL3,TUBB,HDAC2,MLST8 |
| 4.906e-02 | -3.01 | PCF11 (PCF11, cleavage and polyadenylation factor subunit) | protein interactions | 51585 | 40 | 11 | 17029 | 2761 |
RPA2,MRPL50,CDKN2AIP,USF1,EWSR1,RANGAP1,PDCD4,PABPC4,MAPK3,RPA1,SRPK2 |
| 4.906e-02 | -3.01 | Smad3 (SMAD family member 3) | protein interactions | 17127 | 40 | 11 | 17029 | 2761 |
EIF4ENIF1,SMAD2,POLR2G,DHX16,PPIL2,STX18,ROCK1,SMURF1,RBM4,SMAD4,FUBP1 |
| 4.906e-02 | -3.01 | aldosterone_producing | COSMIC cancer mutations | aldosterone_producing | 92 | 20 | 17385 | 2587 |
SAMD4B,DNMT3A,NRAS,LONRF3,KRAS,SYVN1,PPWD1,MYO9B,MEN1,GNAS,DLG5,ATP1A1,OSBPL8,MED15,TYW5,PTPN11,YY1,PITRM1,HRAS,ABCC5 |
| 4.907e-02 | -3.01 | mRNA destabilization | biological process | GO:0061157 | 23 | 7 | 17256 | 2622 |
KHSRP,YTHDF3,UPF1,CNOT6L,HNRNPR,METTL3,METTL14 |
| 4.907e-02 | -3.01 | nucleotide-sugar biosynthetic process | biological process | GO:0009226 | 23 | 7 | 17256 | 2622 |
NANS,AMDHD2,UAP1,GNPNAT1,UGP2,TSTA3,GNPDA1 |
| 4.907e-02 | -3.01 | negative regulation of cell cycle arrest | biological process | GO:0071157 | 23 | 7 | 17256 | 2622 |
TFAP4,CCNK,MIF,ZNF268,CHEK2,MDM2,HMGN5 |
| 4.907e-02 | -3.01 | Rac protein signal transduction | biological process | GO:0016601 | 23 | 7 | 17256 | 2622 |
RHOG,WASF2,CYFIP1,NCKAP1,ELMO1,ALS2,RAC1 |
| 4.907e-02 | -3.01 | positive regulation of G2/M transition of mitotic cell cycle | biological process | GO:0010971 | 23 | 7 | 17256 | 2622 |
DTL,RAD51C,BRD4,CCNB1,RAB11A,MECP2,APP |
| 4.907e-02 | -3.01 | porphyrin-containing compound biosynthetic process | biological process | GO:0006779 | 23 | 7 | 17256 | 2622 |
COX15,ATP5IF1,SLC25A39,RSAD1,TMEM14C,CPOX,UROD |
| 4.908e-02 | -3.01 | PRNP (prion protein) | protein interactions | 5621 | 95 | 22 | 17029 | 2761 |
PLK3,ZBED3,DDX47,CYLD,CIRBP,CSNK2A1,ARF1,WDR5,MPG,RPSA,PABPC4,ARHGAP15,LMNA,APLP2,PSMD2,HSPA4,TBPL1,CLU,ERI3,UTP4,PABPC1,ADAM23 |
| 4.908e-02 | -3.01 | PPM1H (protein phosphatase, Mg2+/Mn2+ dependent 1H) | protein interactions | 57460 | 95 | 22 | 17029 | 2761 |
MIOS,NF1,FAM53C,DENND4C,BLM,STX16,USP21,GIGYF1,RTKN,ZBTB21,TPD52L2,TSC1,GOLGA4,WDR11,FAM110A,HDAC7,KIF13B,ITGB1,YWHAZ,CDC25B,LMAN1,YWHAH |
| 4.910e-02 | -3.01 | DNA-templated transcription, initiation | biological process | GO:0006352 | 215 | 42 | 17256 | 2622 |
NAT14,RORB,CCNC,POLR2K,SMARCA4,TAF6L,THRAP3,NOTCH2,CCNB1,GTF2F1,RRN3,MED8,MED10,CD3EAP,POLR1B,MAML1,ZNRD1,GTF2H2,POLR2I,POLR2L,POLR2G,BAZ2A,POLR2D,E2F3,CBFB,TRIM28,POLR2A,TWISTNB,RXRB,MAPK3,UBTF,TAF2,POLR2J,MED15,TBPL1,CRCP,RBPJ,TAF12,ZNF45,TAF6,E2F2,NRBP1 |
| 4.910e-02 | -3.01 | Bcl-2 | pfam domains | PF00452 | 10 | 4 | 17054 | 2545 |
BAK1,BCL2,MCL1,BCL2L1 |
| 4.910e-02 | -3.01 | Cofilin_ADF | pfam domains | PF00241 | 10 | 4 | 17054 | 2545 |
GMFG,TWF2,CFL1,GMFB |
| 4.910e-02 | -3.01 | WWE | pfam domains | PF02825 | 10 | 4 | 17054 | 2545 |
PARP12,HUWE1,ZC3HAV1,DTX4 |
| 4.910e-02 | -3.01 | EMP24_GP25L | pfam domains | PF01105 | 10 | 4 | 17054 | 2545 |
TMED7,TMED3,TMED10,TMED2 |
| 4.920e-02 | -3.01 | UBA | prosite domains | PS50030 | 41 | 10 | 12060 | 1670 |
UBQLN4,HUWE1,UBXN1,RAD23B,UBQLN2,MARK2,DHX57,USP5,USP13,RAD23A |
| 4.925e-02 | -3.01 | protein kinase complex | cellular component | GO:1902911 | 98 | 21 | 18223 | 2701 |
BCCIP,CCNC,PRKAB1,RB1CC1,PRKAA1,CDK13,CCNL2,CCNB1,ERC1,CCNK,RB1,CCNA2,PRDX3,CAB39,ATG13,MAP3K5,GTF2H2,CDK2,CDK12,PHKG2,WDR41 |
| 4.947e-02 | -3.01 | KEGG_LONG_TERM_POTENTIATION | MSigDB lists | KEGG_LONG_TERM_POTENTIATION | 69 | 16 | 17377 | 2626 |
CALM2,PPP3CA,RAP1A,NRAS,PPP1R12A,RPS6KA1,RAF1,PPP3R1,KRAS,PPP3CB,MAPK1,PRKACA,MAP2K2,HRAS,CAMK2G,MAPK3 |
| 4.947e-02 | -3.01 | CHESLER_BRAIN_QTL_CIS | MSigDB lists | CHESLER_BRAIN_QTL_CIS | 69 | 16 | 17377 | 2626 |
MAPRE1,SCOC,DCAF8,PTTG1,GLO1,PDXDC1,ABHD14A,AKAP1,BCAT2,NUDT19,C4orf3,TULP3,CANT1,MRPL48,TCEA1,ALDH9A1 |
| 4.947e-02 | -3.01 | chr9q22 | MSigDB lists | chr9q22 | 69 | 16 | 17377 | 2626 |
RORB,SEC61B,ZNF367,NOL8,NFIL3,GADD45G,XPA,HABP4,SECISBP2,SMC2,BICD2,PTPDC1,TSTD2,NAA35,RMI1,ZNF189 |
| 4.959e-02 | -3.00 | TBP_dom_sf | interpro domains | IPR012295 | 10 | 4 | 18492 | 2768 |
AP2B1,AP1B1,COPG2,TBPL1 |
| 4.959e-02 | -3.00 | Flavoprotein-like_sf | interpro domains | IPR029039 | 10 | 4 | 18492 | 2768 |
NQO1,NQO2,TYW1,TYW1B |
| 4.959e-02 | -3.00 | ADF-H | interpro domains | IPR002108 | 10 | 4 | 18492 | 2768 |
GMFG,TWF2,CFL1,GMFB |
| 4.959e-02 | -3.00 | Band_7/SPFH_dom_sf | interpro domains | IPR036013 | 10 | 4 | 18492 | 2768 |
PHB2,ERLIN1,FLOT1,STOML2 |
| 4.959e-02 | -3.00 | CTLH_C | interpro domains | IPR006595 | 10 | 4 | 18492 | 2768 |
RMND5A,GID8,MKLN1,SMU1 |
| 4.959e-02 | -3.00 | HAT | interpro domains | IPR003107 | 10 | 4 | 18492 | 2768 |
PRPF39,PDCD11,XAB2,CRNKL1 |
| 4.959e-02 | -3.00 | MIF4G-like_typ-3 | interpro domains | IPR003890 | 10 | 4 | 18492 | 2768 |
UPF2,MIF4GD,EIF4G2,PAIP1 |
| 4.959e-02 | -3.00 | Blc2_fam | interpro domains | IPR026298 | 10 | 4 | 18492 | 2768 |
BAK1,BCL2,MCL1,BCL2L1 |
| 4.968e-02 | -3.00 | FOSTER_KDM1A_TARGETS_DN | MSigDB lists | FOSTER_KDM1A_TARGETS_DN | 193 | 38 | 17377 | 2626 |
UBE2D3,POLA2,LZTR1,KRBA1,SCYL1,VPS45,TIA1,CHKB,AGFG1,SLC25A44,SNN,AP1B1,GFM2,TUBGCP2,SUB1,SHC1,PIK3R2,CORO1A,UBE3B,F2R,SGCB,SAP30,TK1,IDH3A,BTBD1,ANKZF1,MTHFD2,FAM110A,FASTK,QARS,HAGHL,TFDP1,DUSP11,SPRYD4,WIPI2,RUVBL2,MZT2B,TMEM131 |
| 4.968e-02 | -3.00 | GSE9878_CTRL_VS_EBF_TRANSDUCED_PAX5_KO_PRO_BCELL_UP | MSigDB lists | GSE9878_CTRL_VS_EBF_TRANSDUCED_PAX5_KO_PRO_BCELL_UP | 193 | 38 | 17377 | 2626 |
MIB2,LIME1,WDR13,FLYWCH2,MAGED1,TRIO,ABHD14B,SIRT2,NHLRC3,METTL3,MXD1,SRXN1,GOLM1,GLIS2,ETV6,TAP2,CNN2,SLC35C2,F2R,SEPT9,CREG1,CIC,EMB,LDB1,EMP3,PLEC,EIF3A,ABHD5,SGSH,SERTAD2,BRWD1,ACOX1,HAGHL,APPL2,HEXA,EYA2,SSRP1,SVIP |
| 4.985e-02 | -3.00 | GO_POSITIVE_REGULATION_OF_KINASE_ACTIVITY | MSigDB lists | GO_POSITIVE_REGULATION_OF_KINASE_ACTIVITY | 462 | 83 | 17377 | 2626 |
CCNC,TXN,TRAF7,RAF1,MAGED1,RAC1,TPX2,CCNL2,S1PR2,MAPK14,PRKACA,LYN,PARK7,CRKL,CALM2,CDK5,RAP1A,SHC1,CDC42,RALB,KIF14,ADCY9,CDKN1B,CDC25B,F2R,ABI1,DVL2,ADCY7,COPS8,BAK1,PSRC1,CDC6,PPP2CA,MAP3K4,TAB2,RPS27A,AXIN1,GADD45B,RPLP1,CAB39,ADAM9,STK11,CLU,MAPK1,LRP8,MIF,HSPH1,CLSPN,ZFP91,VAV2,GADD45G,PRKAA1,CIB1,PSEN1,CCNK,FGFR3,PDCD10,PTPN11,MDFIC,MAP3K14,GNAI2,TGFB1,PDPK1,TELO2,ADAM17,RHOA,MAPKAPK3,PRKAR1B,JTB,MAP4K3,KRAS,ADRB2,ZP3,MARK2,MAP2K2,MAPK3,CSK,OSBPL8,PKD2,MAP3K5,CD81,HRAS,ALS2 |
| 4.986e-02 | -3.00 | GO_HYDROGEN_TRANSPORT | MSigDB lists | GO_HYDROGEN_TRANSPORT | 113 | 24 | 17377 | 2626 |
COX5B,COX15,UQCR10,ATP6V0A1,NDUFA4,COX4I1,SLC17A5,ATP6V1B2,CYB5A,STOML2,ATP6V0B,ATP6V1D,ATP1A1,COX7A2L,COX8A,COX5A,ATP6V0A2,UQCRH,ATP6V0C,ATP6V1C1,SLC35A1,ATP6V0D1,ATP6V0E1,ATP6V1G1 |
| 4.991e-02 | -3.00 | PID_HEDGEHOG_GLI_PATHWAY | MSigDB lists | PID_HEDGEHOG_GLI_PATHWAY | 48 | 12 | 17377 | 2626 |
CSNK1G2,CSNK1G1,RAB23,RBBP4,PRKACA,CSNK1A1,ARRB2,GNAI2,CSNK1D,CSNK1G3,HDAC2,SAP30 |
| 4.991e-02 | -3.00 | GO_POSITIVE_REGULATION_OF_RESPONSE_TO_NUTRIENT_LEVELS | MSigDB lists | GO_POSITIVE_REGULATION_OF_RESPONSE_TO_NUTRIENT_LEVELS | 48 | 12 | 17377 | 2626 |
SCOC,RALB,PIP4K2C,GBA,ADRB2,BECN1,LRSAM1,PARK7,PIP4K2A,EPM2A,SH3GLB1,MAPK3 |
| 4.991e-02 | -3.00 | GO_POSITIVE_REGULATION_OF_RESPONSE_TO_EXTRACELLULAR_STIMULUS | MSigDB lists | GO_POSITIVE_REGULATION_OF_RESPONSE_TO_EXTRACELLULAR_STIMULUS | 48 | 12 | 17377 | 2626 |
SCOC,RALB,PIP4K2C,GBA,ADRB2,BECN1,LRSAM1,PARK7,PIP4K2A,EPM2A,SH3GLB1,MAPK3 |
| 4.991e-02 | -3.00 | GO_CARBOHYDRATE_DERIVATIVE_TRANSPORT | MSigDB lists | GO_CARBOHYDRATE_DERIVATIVE_TRANSPORT | 48 | 12 | 17377 | 2626 |
GUK1,SLC35B4,SLC25A19,GLTP,SLC29A1,SLC35B2,SLC17A5,SLC35B1,SCARB1,SLC35C2,SLC35A1,SLC50A1 |
| 4.991e-02 | -3.00 | GO_POSITIVE_REGULATION_OF_INTRINSIC_APOPTOTIC_SIGNALING_PATHWAY | MSigDB lists | GO_POSITIVE_REGULATION_OF_INTRINSIC_APOPTOTIC_SIGNALING_PATHWAY | 48 | 12 | 17377 | 2626 |
PTPN2,NCK1,SIAH1,PLAGL2,MCL1,BCL2,BCLAF1,BCL2L1,CLU,PRKRA,BCAP31,PARK7 |
| 4.991e-02 | -3.00 | FAELT_B_CLL_WITH_VH3_21_DN | MSigDB lists | FAELT_B_CLL_WITH_VH3_21_DN | 48 | 12 | 17377 | 2626 |
MOAP1,SMAD2,HMGN4,TAB2,PSMD8,RABGAP1L,HEBP2,ASAH1,CDKN1B,PLCL2,CTDSP2,SERP1 |
| 4.991e-02 | -3.00 | MORI_IMMATURE_B_LYMPHOCYTE_UP | MSigDB lists | MORI_IMMATURE_B_LYMPHOCYTE_UP | 48 | 12 | 17377 | 2626 |
GNS,ATP6V0B,CTSS,BIRC3,PML,MCL1,GGA2,LYN,PIP4K2A,SMAP2,CAPN1,ADCY7 |
| 4.991e-02 | -3.00 | YANG_BREAST_CANCER_ESR1_LASER_DN | MSigDB lists | YANG_BREAST_CANCER_ESR1_LASER_DN | 48 | 12 | 17377 | 2626 |
PRKD3,SGCE,IFRD1,SYNCRIP,TTLL4,KIF14,MCCC1,ANP32E,FXR1,ODC1,HDAC2,PRNP |
| 4.993e-02 | -3.00 | SPAG9 (sperm associated antigen 9) | protein interactions | 9043 | 90 | 21 | 17029 | 2761 |
PLK1,MND1,MAX,IVNS1ABP,MTA2,EYA1,ANK3,KLC1,RRM2,ATG2B,NENF,BRCA1,SOX4,MCM2,MAP1LC3B,MAPK14,CDK11A,SCARB2,SMC3,HUWE1,ABRAXAS2 |
| 4.993e-02 | -3.00 | ZNF408 (zinc finger protein 408) | protein interactions | 79797 | 90 | 21 | 17029 | 2761 |
MIF,SEPHS2,TRIM41,AGGF1,CXXC1,KIAA0232,ANAPC2,ERBIN,CDC23,SHCBP1,CHAF1A,PRNP,DDX56,DAP3,CDC16,CDC27,LTBP4,RPS27A,MTMR4,ZNF330,UPF2 |
| 4.998e-02 | -3.00 | Arf6 downstream pathway | Pathway Interaction DB | arf6downstreampathway | 15 | 6 | 2226 | 426 |
RHOA,ARF1,MAPK1,RAB11A,RAC1,MAPK3 |